Modified sequence Experiment N duplicates Sequence Length Missed cleavages Proteins Leading proteins Gene names Protein names Phospho (STY) Acetyl (K) All Phospho (STY) Probabilities All Acetyl (K) Probabilities Max Score Min PEP Intensity Reporter intensity corrected 1 Reporter intensity corrected 2 Reporter intensity corrected 3 Reporter intensity corrected 4 Reporter intensity corrected 5 Reporter intensity corrected 6 Reporter intensity corrected 7 Reporter intensity corrected 8 Reporter intensity corrected 9 Reporter intensity corrected 10 Phosphoproteome Acetylproteome Fullproteome TMT Channel Normal 1 TMT Channel Normal 2 TMT Channel Normal 3 TMT Channel Normal 4 TMT Channel Normal 5 TMT Channel Normal 6 TMT Channel Normal 7 TMT Channel Normal 8 TMT Channel Normal 9 TMT Channel Normal 10 TMT Channel Ratio 1 TMT Channel Ratio 2 TMT Channel Ratio 3 TMT Channel Ratio 4 TMT Channel Ratio 5 TMT Channel Ratio 6 TMT Channel Ratio 7 TMT Channel Ratio 8 TMT Channel Ratio 9 TMT Channel Ratio 10 Curve signal Log EC50 Curve slope Curve top Curve bottom R2 Curve RMSE Log EC50 error Curve slope error Curve top error Curve bottom error EC50 pEC50 Curve effect size Regulation (ac)AAAAAAAAAAGAAGGRGS(ph)GPGR ddPTM_HeLa_Curcumin_4h_R1 1 AAAAAAAAAAGAAGGRGSGPGR 22 1 Q86U42-2;Q86U42 Q86U42-2 PABPN1 Polyadenylate-binding protein 2 1 0 AAAAAAAAAAGAAGGRGS(1)GPGR 92.563 2.10E-11 0 453.33 273.7 282.4 271.1 370.68 332 158.24 244.84 278.26 306.68 TRUE FALSE FALSE 417.4484521 297.3574084 292.8659924 269.97826 366.2598831 263.1394576 162.6797885 319.4905889 247.7355742 317.3371072 1.315473176 0.937039513 0.92288606 0.85076171 1.154166578 0.829211119 0.512640296 1.006786101 0.780670046 1 8.30987242 -6.094918454 0.756281002 1.138518211 0.783912685 0 0.208559858 0.614431562 0.674216838 0.038869112 0.1088225 8.04E-07 6.094918454 -0.354605525 (ac)AAAAAAAGDS(ph)DS(ph)WDADAFSVEDPVRK ddPTM_HeLa_Curcumin_4h_R1 2 AAAAAAAGDSDSWDADAFSVEDPVRK 26 1 O75822-2;O75822;O75822-3 O75822-2 EIF3J Eukaryotic translation initiation factor 3 subunit J 2 0 AAAAAAAGDS(1)DS(1)WDADAFSVEDPVRK;AAAAAAAGDS(1)DS(1)WDADAFSVEDPVRK ; 61.903 1.63E-05 12380200 3308.4 3140.6 2793.64 2511.86 2919.7 3736.1 2895.01 3739.6 3510.3 2980.9 TRUE FALSE FALSE 3046.536649 3412.05947 2897.174756 2501.466589 2884.884484 2961.190745 2976.236189 4879.786825 3125.228872 3084.486053 0.987696685 1.106200323 0.939273093 0.810983271 0.935288549 0.960027277 0.964905056 1.58204211 1.013208949 1 11.59081441 -4.260685206 24.98291686 0.978005754 1.582042299 0.871162966 0.070687425 16.30932798 540162.5858 0.010088274 0.08125431 5.49E-05 4.260685206 0.604036545 (ac)AAAAAAAGDS(ph)DSWDADAFSVEDPVR ddPTM_HeLa_Curcumin_4h_R1 2 AAAAAAAGDSDSWDADAFSVEDPVR 25 0 O75822-2;O75822;O75822-3 O75822-2 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 0 AAAAAAAGDS(0.807)DS(0.193)WDADAFSVEDPVR;AAAAAAAGDS(0.947)DS(0.053)WDADAFSVEDPVR ; 197.1 1.19E-130 0 228.31 172.92 105.79 121.32 123.58 129.57 0 0 280.77 55.15 TRUE FALSE FALSE 210.2390226 187.8664343 109.7106705 120.81801 122.1063892 102.6957214 0 0 249.9702335 57.06645839 3.684108468 3.292064017 1.922507083 2.117145752 2.139722573 1.799581126 0 0 4.380335498 1 5.834571125 -4.846931667 3.114870227 2.322301029 4.51E-14 0.529416181 0.951522175 0.178241447 3.398079797 0.148452257 0.562009388 1.42E-05 4.846931667 -2.322301029 (ac)AAAAAAAGDS(ph)DSWDADAFSVEDPVRK ddPTM_HeLa_Curcumin_4h_R1 12 AAAAAAAGDSDSWDADAFSVEDPVRK 26 1 O75822-2;O75822;O75822-3 O75822-2 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 0 AAAAAAAGDS(0.999)DS(0.001)WDADAFSVEDPVRK;AAAAAAAGDS(0.856)DS(0.144)WDADAFSVEDPVRK;AAAAAAAGDS(0.987)DS(0.013)WDADAFSVEDPVRK;AAAAAAAGDS(0.84)DS(0.16)WDADAFSVEDPVRK;AAAAAAAGDS(0.845)DS(0.155)WDADAFSVEDPVRK;AAAAAAAGDS(0.975)DS(0.025)WDADAFSVEDPVRK;AAAAAAAGDS(0.792)DS(0.208)WDADAFSVEDPVRK;AAAAAAAGDS(0.993)DS(0.007)WDADAFSVEDPVRK;AAAAAAAGDS(0.5)DS(0.5)WDADAFSVEDPVRK;AAAAAAAGDS(0.842)DS(0.158)WDADAFSVEDPVRK;AAAAAAAGDS(0.728)DS(0.272)WDADAFSVEDPVRK;AAAAAAAGDS(0.82)DS(0.18)WDADAFSVEDPVRK ;;;;;;;;;;; 129.2 1.79E-19 815484500 28102.01 24697.6 24612.24 27690.21 26915.37 37260.05 28068.55 24698.26 30567.57 27853.15 TRUE FALSE FALSE 25877.70626 26832.35049 25524.39127 27575.63525 26594.42179 29531.89562 28856.07797 32228.64578 27214.38405 28821.04489 0.897875367 0.930998532 0.885616443 0.956788186 0.922743152 1.024664294 1.001215538 1.118233079 0.9442539 1 14.81483502 -4.09947185 0.966997683 0.943224192 1.245180994 0.704231787 0.035959232 1.439480401 0.835408615 0.007145584 0.486311333 7.95E-05 4.09947185 0.301956802 (ac)AAAAAAAGDSDS(ph)WDADAFSVEDPVR ddPTM_HeLa_Curcumin_4h_R1 1 AAAAAAAGDSDSWDADAFSVEDPVR 25 0 O75822-2;O75822;O75822-3 O75822-2 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 0 AAAAAAAGDS(0.446)DS(0.554)WDADAFSVEDPVR 65.425 0.00063577 3552000 268.21 300.3 177.45 183.91 245.26 360.63 246.87 219.14 235.26 244.92 TRUE FALSE FALSE 246.9808955 326.2565939 184.0264531 183.1490291 242.3354347 285.8312729 253.7965078 285.9547772 209.4525666 253.4309518 0.974549059 1.28735891 0.726140402 0.72267822 0.956218777 1.12784674 1.001442428 1.12833407 0.826467979 1 7.985448923 -5.275052602 23.36625541 0.968370179 1.077431212 0.138725515 0.159067049 606.8606575 1041640.23 0.022160865 0.049848996 5.31E-06 5.275052602 0.109061033 (ac)AAADGDDSLYPIAVLIDELR ddPTM_HeLa_Curcumin_4h_R1 1 AAADGDDSLYPIAVLIDELR 20 0 P30153;C9J9C1;M0QXG4;M0R0K6 P30153 PPP2R1A Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 0 0 214.61 3.11E-98 41380000 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 (ac)AAAIT(ph)DMADLEELSRLSPLPPGS(ph)PGSAAR ddPTM_HeLa_Curcumin_4h_R1 1 AAAITDMADLEELSRLSPLPPGSPGSAAR 29 1 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 2 0 AAAIT(0.924)DMADLEELS(0.153)RLS(0.162)PLPPGS(0.617)PGS(0.144)AAR 48.232 6.56E-08 3513800 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)AAAMDVDT(ph)PSGTNSGAGKK ddPTM_HeLa_Curcumin_4h_R1 3 AAAMDVDTPSGTNSGAGKK 19 1 P62877 P62877 RBX1 "E3 ubiquitin-protein ligase RBX1;E3 ubiquitin-protein ligase RBX1, N-terminally processed" 1 0 AAAMDVDT(0.913)PS(0.058)GT(0.028)NS(0.002)GAGKK;AAAMDVDT(0.964)PS(0.033)GT(0.003)NSGAGKK;AAAMDVDT(0.956)PS(0.04)GT(0.003)NSGAGKK ;; 84.94 4.17E-05 16809400 3247.82 2943.03 2650.29 3395.62 2759.78 6212.3 5581.9 3531.77 3186.33 2722.73 TRUE FALSE FALSE 2990.75162 3197.412399 2748.512079 3381.569824 2726.871426 4923.798953 5738.513091 4608.590415 2836.797571 2817.344665 1.061549784 1.134902818 0.975568276 1.200268418 0.967887053 1.747673621 2.036851636 1.635792195 1.006904695 1 11.46012035 -5.21741415 5.268489685 1.043028196 1.842612889 0.900920781 0.115061987 0.037045848 2.543202158 0.014441425 0.037182034 6.06E-06 5.21741415 0.799584694 (ac)AAAPQAPGRGS(ph)LRK ddPTM_HeLa_Curcumin_4h_R1 1 AAAPQAPGRGSLRK 14 2 P78345;Q5VUC9;Q5VUC3 P78345 RPP38 Ribonuclease P protein subunit p38 1 0 AAAPQAPGRGS(1)LRK 59.227 0.015183 15282000 1700.8 1626.8 1394.2 1636.2 1331.1 2103.7 1518.1 2114.1 1826.4 1561.9 TRUE FALSE FALSE 1566.179885 1767.413343 1445.870278 1629.429838 1315.227502 1667.368906 1560.6938 2758.679358 1626.048489 1616.175909 0.969065234 1.093577335 0.894624323 1.008200796 0.81378982 1.031675387 0.965670749 1.706917758 1.006108605 1 10.65836852 -4.260828905 24.98376038 0.978460945 1.706917982 0.90142512 0.07252129 9.684529188 396246.5899 0.008997043 0.071854719 5.48E-05 4.260828905 0.728457037 (ac)AAAS(ph)PLRDCQAWK ddPTM_HeLa_Curcumin_4h_R1 1 AAASPLRDCQAWK 13 1 F8WBU8;A9UJP8;Q5R3I4 F8WBU8 TTC38 Tetratricopeptide repeat protein 38 1 0 AAAS(1)PLRDCQAWK 92.906 0.0015198 29566000 1137.1 889.53 914.29 840.68 912.6 1194.1 913.21 743.93 1179.4 1029.1 TRUE FALSE FALSE 1047.097335 966.4170095 948.1743917 837.2014889 901.717841 946.4301997 938.8322148 970.7508324 1050.022771 1064.861148 0.983318188 0.907552136 0.890420684 0.786207188 0.846793821 0.888782731 0.881647543 0.911621984 0.986065434 1 10.05644961 -7.112167678 1.962075803 0.993713277 0.864009112 0.746859781 0.031898728 0.114583681 0.851202586 0.005970061 0.007489239 7.72E-08 7.112167678 -0.129704166 (ac)AADS(ph)DDGAVSAPAASDGGVSK ddPTM_HeLa_Curcumin_4h_R1 1 AADSDDGAVSAPAASDGGVSK 21 0 Q96GM8 Q96GM8 TOE1 Target of EGR1 protein 1 1 0 AADS(1)DDGAVSAPAASDGGVSK 109.1 2.24E-05 7644300 4567.6 3125.1 3563 3801.3 3713.6 4504.9 3091.7 2693.1 4694.7 3956.5 TRUE FALSE FALSE 4206.06964 3395.219719 3695.047914 3785.571228 3669.317745 3570.532959 3178.444781 3514.213792 4179.703156 4093.988081 1.027377109 0.829318418 0.902554634 0.924665913 0.896269768 0.872140536 0.776368841 0.858383982 1.020936816 1 11.99929119 -7.267121396 24.98342734 1.012928082 0.867350229 0.752331655 0.039532522 176.5479803 776267.7303 0.00723365 0.00839252 5.41E-08 7.267121396 -0.145577853 (ac)AAGGAAPETPAIS(ph)PSKR ddPTM_HeLa_Curcumin_4h_R1 4 AAGGAAPETPAISPSKR 17 1 H0YNW5;H0YMM5 H0YNW5 DUT 1 0 AAGGAAPET(0.001)PAIS(0.833)PS(0.166)KR;AAGGAAPET(0.006)PAIS(0.876)PS(0.118)KR;AAGGAAPET(0.007)PAIS(0.845)PS(0.148)KR;AAGGAAPET(0.037)PAIS(0.59)PS(0.373)KR ;;; 141.1 4.00E-05 190138000 12091.1 9035.7 9897.3 10342.4 9679 12825.1 9443.7 10026 11724.2 10329.9 TRUE FALSE FALSE 11134.07668 9816.705646 10264.10264 10299.60589 9563.584247 10165.02969 9708.664806 13082.88125 10438.08459 10688.86326 1.041652083 0.918405017 0.960261386 0.963582903 0.894724165 0.950992584 0.908297222 1.223973114 0.976538322 1 13.38382081 -7.280893212 24.61510664 1.019669039 0.966867974 0.014417893 0.089511914 1340.293093 1695880.323 0.014192927 0.016243854 5.24E-08 7.280893212 -0.052801065 (ac)AAGGDHGS(ph)PDSYR ddPTM_HeLa_Curcumin_4h_R1 4 AAGGDHGSPDSYR 13 0 A0A1B0GTG9;A0A1B0GWF8;A0A1B0GWJ0;A0A1B0GTJ7;A0A0A6YY92;P30566-2;P30566;B4DEP1;A0A1W2PRX2;A0A096LP72;A0A096LNY4;A0A096LNY5 A0A1B0GTG9 ADSL Adenylosuccinate lyase 1 0 AAGGDHGS(0.981)PDS(0.019)YR;AAGGDHGS(0.88)PDS(0.12)YR;AAGGDHGS(0.992)PDS(0.008)YR;AAGGDHGS(0.987)PDS(0.013)YR ;;; 116.9 2.64E-19 73652000 1046.15 887.34 966.26 945.89 908.27 1084.17 775.56 1034.726 1064.66 863.786 TRUE FALSE FALSE 963.3461236 964.0377157 1002.070446 941.9761578 897.4394735 859.3009209 797.3201263 1350.209194 947.8694616 893.8024992 1.077806478 1.078580242 1.121131846 1.053897431 1.004069103 0.961399103 0.892054035 1.510634839 1.06049095 1 9.803812269 -4.250918808 24.99947879 1.032549827 1.510635105 0.840056621 0.063184113 475.5361901 1129970.041 0.009334735 0.180486302 5.61E-05 4.250918808 0.478085278 (ac)AAGGDHGS(ph)PDSYRSPLASR ddPTM_HeLa_Curcumin_4h_R1 1 AAGGDHGSPDSYRSPLASR 19 1 A0A1B0GTG9;A0A1B0GWF8;A0A1B0GWJ0;A0A1B0GTJ7;A0A0A6YY92;P30566-2;P30566;B4DEP1;A0A1W2PRX2;A0A096LP72;A0A096LNY4;A0A096LNY5 A0A1B0GTG9 ADSL Adenylosuccinate lyase 1 0 AAGGDHGS(0.998)PDS(0.001)YRS(0.001)PLASR 55.261 0.0004173 28461000 608.51 763.6 710.5 734.17 500.44 578.16 469.47 606.66 798.59 820.75 TRUE FALSE FALSE 560.3457914 829.6021815 736.831755 731.1321991 494.4725798 458.2430988 482.6420647 791.6278413 710.986675 849.2710014 0.659796214 0.976840349 0.867604986 0.86089387 0.582231795 0.53957229 0.568301595 0.932126306 0.837172909 1 9.730081179 -5.769796454 24.57296739 0.850766576 0.6410407 0.369556418 0.13378413 146.9240206 432013.7913 0.023795159 0.043667025 1.70E-06 5.769796454 -0.209725877 (ac)AAGTAAALAFLS(ph)QESR ddPTM_HeLa_Curcumin_4h_R1 1 AAGTAAALAFLSQESR 16 0 O75607 O75607 NPM3 Nucleoplasmin-3 1 0 AAGT(0.001)AAALAFLS(0.911)QES(0.088)R 89.502 4.20E-08 0 72.475 0 0 0 0 0 0 0 0 73.078 TRUE FALSE FALSE 66.73852727 0 0 0 0 0 0 0 0 75.61745506 0.882580976 0 0 0 0 0 0 0 0 1 6.24064739 -7.277026236 5.029917569 0.948063527 6.33E-29 0.366067474 0.300509736 0.010405032 0.789033376 0.006835737 0.007995983 5.28E-08 7.277026236 -0.948063527 (ac)AALGHLAGEAAAAPGPGT(ph)PCASR ddPTM_HeLa_Curcumin_4h_R1 3 AALGHLAGEAAAAPGPGTPCASR 23 0 A0A3B3IRR6;A0A3B3IT54;A0A3B3ITA3;Q9H7E9;Q9H7E9-2 A0A3B3IRR6 C8orf33 UPF0488 protein C8orf33 1 0 AALGHLAGEAAAAPGPGT(0.998)PCAS(0.002)R;AALGHLAGEAAAAPGPGT(0.995)PCAS(0.005)R;AALGHLAGEAAAAPGPGT(1)PCASR ;; 166.93 7.43E-48 159095000 0 0 60.856 51.225 283.13 0 0 138.69 0 114.58 TRUE FALSE FALSE 0 0 63.11137689 51.01304452 279.7538597 0 0 180.9759425 0 118.5616465 0 0 0.53230854 0.430265993 2.359564564 0 0 1.52642906 0 1 6.889493577 (ac)AALHT(ph)TPDSPAAQLER ddPTM_HeLa_Curcumin_4h_R1 1 AALHTTPDSPAAQLER 16 0 A6NFI3 A6NFI3 ZNF316 Zinc finger protein 316 1 0 AALHT(0.984)T(0.014)PDS(0.003)PAAQLER 139.66 1.38E-10 26060000 0 61.252 57.631 54.334 57.676 220.64 56.831 159.64 222.16 181.98 TRUE FALSE FALSE 0 66.54634995 59.76685556 54.1091803 56.98825137 174.8767769 58.42552491 208.3135011 197.7896038 188.3037915 0 0.353398885 0.317395922 0.287350456 0.302639957 0.928694932 0.310272695 1.106262914 1.050375047 1 7.556918238 -2.59744446 11.28462056 0.504965627 37.8846741 0 0.390253501 0 0 0.056428584 0 0.002526711 2.59744446 37.37970848 (ac)AALHTTPDS(ph)PAAQLER ddPTM_HeLa_Curcumin_4h_R1 2 AALHTTPDSPAAQLER 16 0 A6NFI3 A6NFI3 ZNF316 Zinc finger protein 316 1 0 AALHT(0.001)T(0.001)PDS(0.998)PAAQLER;AALHT(0.047)T(0.186)PDS(0.767)PAAQLER ; 154.81 5.99E-22 43328000 520.959 511 678.34 550.85 442.77 442.79 431.25 387.562 584.382 619.99 TRUE FALSE FALSE 479.7245454 555.168563 703.4798771 548.5707287 437.4902569 350.9503627 443.3497144 505.7278697 520.2767567 641.5346064 0.747776567 0.865375862 1.096557957 0.855091406 0.681943347 0.547048217 0.691076849 0.78830957 0.810987827 1 9.325383281 -5.788232899 4.721327974 0.894226439 0.667168341 0.509932592 0.105546783 0.145446824 7.776490334 0.018697007 0.035728473 1.63E-06 5.788232899 -0.227058098 (ac)AAPAQQTTQPGGGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 AAPAQQTTQPGGGKR 15 1 H3BNW0;Q9NXG2 H3BNW0 THUMPD1 THUMP domain-containing protein 1 0 1 ; AAPAQQTTQPGGGK(1)R;AAPAQQTTQPGGGK(1)R 94.402 2.51E-05 4007000 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)AAPAQQTTQPGGGKR ddPTM_HeLa_Curcumin_4h_R1 1 AAPAQQTTQPGGGKR 15 1 H3BNW0;Q9NXG2 H3BNW0 THUMPD1 THUMP domain-containing protein 1 0 0 87.298 0.0035097 351940 144.48 210.56 65.147 205.16 222.13 209.88 218.39 181.16 339.16 168.47 FALSE FALSE TRUE 133.0442555 228.7598682 67.56140513 204.3111023 219.4812448 166.3485222 224.5174356 236.39485 301.9549965 174.32432 0.763199625 1.312265943 0.387561559 1.172017205 1.259039731 0.95424736 1.287929508 1.356063515 1.732144985 1 7.445630043 -6.038775979 24.99837999 0.884976521 1.202817474 0 0.356570998 480.5950273 309832.8605 0.033573654 0.055682606 9.15E-07 6.038775979 0.317840953 (ac)AAPEEHDS(ph)PTEASQPIVEEEETKTFK ddPTM_HeLa_Curcumin_4h_R1 1 AAPEEHDSPTEASQPIVEEEETKTFK 26 1 F5H1N9;Q9H0S4-2;Q9H0S4 F5H1N9 DDX47 Probable ATP-dependent RNA helicase DDX47 1 0 AAPEEHDS(0.956)PT(0.042)EAS(0.002)QPIVEEEETKTFK 101.71 2.24E-08 8481800 1067.7 407.97 370.18 561.21 238.21 859.53 542.57 670.73 1462.5 1127.8 TRUE FALSE FALSE 983.1904184 443.2331089 383.8991964 558.8878617 235.3695013 681.2537891 557.7930539 875.2324893 1302.067409 1166.990966 0.842500454 0.379808518 0.328965011 0.478913615 0.201689223 0.583769548 0.477975469 0.749990801 1.115747634 1 10.18857768 -7.372293114 3.69651706 0.933507871 0.449012331 0.715571066 0.152268896 0.095549601 2.303667753 0.025484356 0.028970362 4.24E-08 7.372293114 -0.48449554 (ac)AAPRPS(ph)PAISVSVSAPAFYAPQKK ddPTM_HeLa_Curcumin_4h_R1 1 AAPRPSPAISVSVSAPAFYAPQKK 24 2 Q15942;H0Y2Y8;C9IZ41 Q15942 ZYX Zyxin 1 0 AAPRPS(0.448)PAIS(0.448)VS(0.091)VS(0.012)APAFYAPQKK 50.539 2.06E-05 18276000 833.32 457.92 630.72 840.29 743.83 1156.8 963.36 1098.8 651.84 804.31 TRUE FALSE FALSE 767.3618427 497.5005643 654.095038 836.8131026 734.9603131 916.8666402 990.3892888 1433.819062 580.3347828 832.2597126 0.922022094 0.597770812 0.78592659 1.005471117 0.8830901 1.101659285 1.190000277 1.722802438 0.697300102 1 9.700889992 -3.873870138 1.05312983 0.918786727 2.808413115 0.779281015 0.139921914 1.259475311 0.634817422 0.020368818 3.235633694 0.0001337 3.873870138 1.889626388 (ac)AAPRPSPAIS(ph)VSVSAPAFYAPQKK ddPTM_HeLa_Curcumin_4h_R1 1 AAPRPSPAISVSVSAPAFYAPQKK 24 2 Q15942;H0Y2Y8;C9IZ41 Q15942 ZYX Zyxin 1 0 AAPRPS(0.117)PAIS(0.761)VS(0.117)VS(0.005)APAFYAPQKK 55.127 1.89E-05 21680000 341.16 243.15 277.85 452.44 275.72 580.89 505.27 339.19 492.38 361.67 TRUE FALSE FALSE 314.156826 264.1668025 288.1473654 450.5679232 272.4322191 460.406866 519.4465163 442.6074696 438.3671459 374.2380056 0.839457301 0.705879143 0.769957517 1.203960892 0.727965132 1.230251495 1.388011128 1.182689794 1.17135924 1 8.547812268 -5.139150435 5.980646577 0.904476898 1.289919469 0.474654232 0.168787105 0.124908384 5.598407993 0.02071825 0.053853673 7.26E-06 5.139150435 0.385442571 (ac)AASAAAAS(ph)AAAASAASGSPGPGEGSAGGEKR ddPTM_HeLa_Curcumin_4h_R1 2 AASAAAASAAAASAASGSPGPGEGSAGGEKR 31 1 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 0 AASAAAAS(0.948)AAAAS(0.009)AAS(0.005)GS(0.038)PGPGEGSAGGEKR;AAS(0.18)AAAAS(0.422)AAAAS(0.377)AAS(0.008)GS(0.012)PGPGEGS(0.001)AGGEKR ; 109.19 1.18E-12 629870000 3347.1 2917.9 2753.2 3284.13 3325.94 3570.04 2446.66 1749.47 3568.31 3216.95 TRUE FALSE FALSE 3082.173503 3170.110274 2855.236014 3270.54114 3286.280338 2829.573461 2515.306695 2282.875349 3176.87532 3328.738773 0.925928321 0.952345765 0.857753104 0.982516612 0.987244888 0.850043712 0.75563355 0.685807901 0.95437808 1 11.70075994 -4.851045533 1.98822442 0.957743519 0.695648708 0.842995395 0.039931008 0.10611348 0.789055389 0.00655174 0.033040639 1.41E-05 4.851045533 -0.262094811 (ac)AASAAAASAAAAS(ph)AASGSPGPGEGSAGGEKR ddPTM_HeLa_Curcumin_4h_R1 2 AASAAAASAAAASAASGSPGPGEGSAGGEKR 31 1 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 0 AAS(0.003)AAAAS(0.229)AAAAS(0.254)AAS(0.254)GS(0.254)PGPGEGS(0.004)AGGEKR;AAS(0.012)AAAAS(0.087)AAAAS(0.72)AAS(0.092)GS(0.087)PGPGEGS(0.001)AGGEKR ; 42.738 1.53E-05 11513000 1753.07 1461.15 1739.24 1536.61 1655.69 1912.55 1538.95 1398.19 1543.86 1512.05 TRUE FALSE FALSE 1614.31266 1587.445295 1803.697764 1530.251915 1635.946978 1515.865571 1582.128795 1824.491695 1374.502421 1564.593625 1.031777603 1.014605499 1.15282188 0.978050716 1.045605039 0.968855776 1.011207492 1.166112187 0.878504424 1 10.61157228 -3.13653408 0.006600494 6.46E-08 2.126736579 0.169035138 0.073188349 33944.74719 26.22283296 3960.47022 4504.266654 0.000730241 3.13653408 2.126736515 (ac)AASAAAASAAAASAAS(ph)GSPGPGEGSAGGEKR ddPTM_HeLa_Curcumin_4h_R1 1 AASAAAASAAAASAASGSPGPGEGSAGGEKR 31 1 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 0 AAS(0.014)AAAAS(0.242)AAAAS(0.114)AAS(0.336)GS(0.287)PGPGEGS(0.006)AGGEKR 52.226 1.45E-08 627750000 3328.3 2698.5 2907.9 3009.4 2758.6 3662.6 2766 1974.3 3660.4 3033.2 TRUE FALSE FALSE 3064.861543 2931.746316 3015.669332 2996.9479 2725.705497 2902.935474 2843.606516 2576.254981 3258.863278 3138.603474 0.976504859 0.934092612 0.960831579 0.954866687 0.868445319 0.924913102 0.906010122 0.820828436 1.038316342 1 11.61590706 -1 0.193550092 1.009583114 0.240800646 0.784831491 0.027820297 16.00376709 0.180632859 0.024712552 3.721596283 0.1 1 -0.768782467 (ac)AASAAAASAAAASAASGS(ph)PGPGEGSAGGEKR ddPTM_HeLa_Curcumin_4h_R1 1 AASAAAASAAAASAASGSPGPGEGSAGGEKR 31 1 Q13263-2;Q13263 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 0 AAS(0.003)AAAAS(0.048)AAAAS(0.014)AAS(0.077)GS(0.853)PGPGEGS(0.006)AGGEKR 57.882 6.39E-11 57931000 1033.2 882.2 875.93 910.45 758.68 870.82 891.17 749.84 1252.7 887.17 TRUE FALSE FALSE 951.4211298 958.453437 908.3927363 906.6827991 749.6332365 690.2021158 916.1738317 978.4627642 1115.281944 917.9990915 1.036407485 1.044067958 0.989535551 0.987672872 0.816594748 0.751854901 0.998011698 1.065864632 1.214905281 1 9.842348916 -5.958505947 11.05461561 1.016906916 0.903104829 0.277353038 0.103544821 0.602019884 157.660597 0.012628401 0.022890851 1.10E-06 5.958505947 -0.113802088 (ac)AASPGS(ph)GSANPR ddPTM_HeLa_Curcumin_4h_R1 1 AASPGSGSANPR 12 0 Q6UUV7;Q6UUV7-3;H0YK33 Q6UUV7 CRTC3 CREB-regulated transcription coactivator 3 1 0 AAS(0.186)PGS(0.731)GS(0.083)ANPR 56.414 0.010255 3695100 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)AATLGAGT(ph)PPRPQAR ddPTM_HeLa_Curcumin_4h_R1 2 AATLGAGTPPRPQAR 15 1 A0A075B730 A0A075B730 EPPK1 1 0 AATLGAGT(1)PPRPQAR;AATLGAGT(1)PPRPQAR ; 93.228 0.00018907 125183000 249.54 304.03 123.04 304.32 242.44 244.02 194.766 0 209.474 299.47 TRUE FALSE FALSE 229.7886457 330.3089985 127.5999706 303.0608045 239.5490613 193.4075013 200.2306098 0 186.4952263 309.8765602 0.741548975 1.065937347 0.411776775 0.978004933 0.773046729 0.624143695 0.64616249 0 0.601837151 1 8.27554982 -4.442347083 1.417094976 0.852915674 5.16E-36 0.529774824 0.205391582 0.470505833 1.071178714 0.027376125 0.514094181 3.61E-05 4.442347083 -0.852915674 (ac)AAVK(ac)TLNPK ddPTM_HeLa_Curcumin_4h_R1 2 AAVKTLNPK 9 1 P40227;P40227-2 P40227 CCT6A T-complex protein 1 subunit zeta 0 1 ; AAVK(1)TLNPK;AAVK(1)TLNPK 40.352 0.00028054 6048900 10186.8 9062.3 8278.4 8155.4 7799.6 9706.1 7023.4 6681.1 9509.5 8491.1 FALSE TRUE FALSE 9380.504031 9845.604831 8585.204786 8121.655116 7706.594864 7692.94545 7220.457701 8718.136634 8466.331642 8786.165093 1.067644863 1.12058045 0.977127643 0.924368599 0.877128392 0.87557488 0.821798546 0.992257321 0.96359806 1 13.10101789 -6.322145782 2.629309183 1.039518214 0.888140384 0.575040436 0.056321328 0.134692551 1.828816861 0.008343826 0.013714117 4.76E-07 6.322145782 -0.15137783 (ac)ACGLVASNLNLKPGECLR ddPTM_HeLa_Curcumin_4h_R1 1 ACGLVASNLNLKPGECLR 18 1 P09382;F8WEI7 P09382 LGALS1 Galectin-1 0 0 49.149 0.0077108 872220 0 0 0 0 0 145.68 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 115.4643258 0 0 0 0 0 (ac)ADDVDQQQTTNTVEEPLDLIR ddPTM_HeLa_Curcumin_4h_R1 2 ADDVDQQQTTNTVEEPLDLIR 21 0 P62310 P62310 LSM3 U6 snRNA-associated Sm-like protein LSm3 0 0 ; ; 249.33 2.70E-138 13817000 123.96 0 0 0 0 140.99 0 0 51.428 0 FALSE FALSE TRUE 114.1484352 0 0 0 0 111.7470847 0 0 45.78647707 0 0 (ac)ADEAALALQPGGS(ph)PSAAGADREAASSPAGEPLR ddPTM_HeLa_Curcumin_4h_R1 1 ADEAALALQPGGSPSAAGADREAASSPAGEPLR 33 1 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 0 ADEAALALQPGGS(0.499)PS(0.499)AAGADREAAS(0.001)S(0.001)PAGEPLR 59.048 1.64E-10 29541000 0 0 0 69.84 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 69.55102059 0 0 0 0 0 0 0 (ac)ADEAALALQPGGSPS(ph)AAGADREAASSPAGEPLR ddPTM_HeLa_Curcumin_4h_R1 1 ADEAALALQPGGSPSAAGADREAASSPAGEPLR 33 1 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 0 ADEAALALQPGGS(0.39)PS(0.607)AAGADREAAS(0.001)S(0.002)PAGEPLR 50.58 1.34E-07 29639000 0 0 0 0 0 0 72.842 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 74.88575048 0 0 0 0 (ac)ADEK(ac)PKEGVK ddPTM_HeLa_Curcumin_4h_R1 2 ADEKPKEGVK 10 2 P61956-2;P61956 P61956-2 SUMO2 Small ubiquitin-related modifier 2 0 1 ; ADEK(0.952)PK(0.048)EGVK;ADEK(0.995)PK(0.005)EGVK 105.1 1.80E-06 116473000 23245.1 17648 18284.1 19445.3 17042 24972 24517.5 19479.4 24791.1 19742.3 FALSE TRUE FALSE 21405.22581 19173.41448 18961.72483 19364.8405 16838.78528 19792.52571 25205.39506 25418.57939 22071.57835 20428.34346 1.047819949 0.938569225 0.928206679 0.947939834 0.824285401 0.968875707 1.233844297 1.244280009 1.08043897 1 14.3182846 -4.758060642 24.91072766 0.987917686 1.239062281 0.709354947 0.068619191 37.15356005 273911.0858 0.01047681 0.036223355 1.75E-05 4.758060642 0.251144595 (ac)ADELS(ph)EKQVYDAHTK ddPTM_HeLa_Curcumin_4h_R1 2 ADELSEKQVYDAHTK 15 1 C9JKI3;Q03135-2 C9JKI3 CAV1 Caveolin;Caveolin-1 1 0 ADELS(1)EKQVYDAHTK;ADELS(0.805)EKQVY(0.195)DAHTK ; 79.659 0.0012559 75001000 4684 3615.39 4262.7 6019.6 3836.16 6481 2567.41 1594.06 6899 5117.1 TRUE FALSE FALSE 4313.256457 3927.888202 4420.679412 5994.69249 3790.416297 5136.767544 2639.444615 2080.081556 6142.19696 5294.918844 0.81460294 0.741822173 0.834890872 1.132159466 0.715859187 0.970131497 0.498486321 0.392844842 1.160017205 1 12.37039286 -4.690129547 5.0430956 0.897719395 0.422760514 0.630523699 0.145205831 0.083570337 3.869055353 0.017242703 0.067575913 2.04E-05 4.690129547 -0.474958881 (ac)ADGDS(ph)GS(ph)ERGGGGGPCGFQPASR ddPTM_HeLa_Curcumin_4h_R1 2 ADGDSGSERGGGGGPCGFQPASR 23 1 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 2 0 ADGDS(1)GS(1)ERGGGGGPCGFQPASR;ADGDS(1)GS(1)ERGGGGGPCGFQPASR ; 106.76 6.92E-06 136005000 127.35 0 0 290.92 143.63 0 135 126.22 203.37 100.85 TRUE FALSE FALSE 117.2701131 0 0 289.7162501 141.9173061 0 138.7877367 164.703897 181.0608198 104.35453 1.123766387 0 0 2.776269033 1.359953478 0 1.329963699 1.578310946 1.73505472 1 6.705349419 (ac)ADGDS(ph)GSERGGGGGPCGFQPASR ddPTM_HeLa_Curcumin_4h_R1 1 ADGDSGSERGGGGGPCGFQPASR 23 1 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 0 ADGDS(0.5)GS(0.5)ERGGGGGPCGFQPASR 72.523 1.10E-05 76929000 167.87 0 192.03 252.22 142.51 241.98 186.82 135.75 281.32 122.57 TRUE FALSE FALSE 154.5829124 0 199.1468007 251.1763805 140.8106613 191.7906203 192.0616664 177.1395501 250.4598998 126.8292984 1.21882652 0 1.570195556 1.980428684 1.110237643 1.512194917 1.51433201 1.396676891 1.974779511 1 6.986744246 (ac)ADGDSGS(ph)ERGGGGGPCGFQPASR ddPTM_HeLa_Curcumin_4h_R1 1 ADGDSGSERGGGGGPCGFQPASR 23 1 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 0 ADGDS(0.255)GS(0.745)ERGGGGGPCGFQPASR 51.073 0.0014047 62044000 180.06 0 172.66 216.29 175.55 0 263.57 228.04 224.79 186.08 TRUE FALSE FALSE 165.808061 0 179.0589315 215.3950493 173.4566809 0 270.9650648 297.5683462 200.1310994 192.5462661 0.861133609 0 0.929952759 1.118666457 0.900857152 0 1.407272497 1.545438155 1.039392263 1 7.589061336 -6.539219887 24.99110223 0.843580057 0.963672867 0.043493913 0.476089357 1246.743612 1906684.118 0.07677243 0.108588426 2.89E-07 6.539219887 0.12009281 (ac)ADGGS(ph)PFLGRR ddPTM_HeLa_Curcumin_4h_R1 2 ADGGSPFLGRR 11 1 O60504-2;E5RIA0;E5RJP2 O60504-2 SORBS3 Vinexin 1 0 ADGGS(1)PFLGRR;ADGGS(1)PFLGRR ; 86.189 0.0072692 216226000 881.05 530.44 926.08 1002.51 746.741 1037.18 875.62 572.39 1255.45 1131.44 TRUE FALSE FALSE 811.3139628 576.28887 960.4013395 998.3618793 737.8366013 822.0571766 900.1875406 746.909076 1117.730276 1170.757456 0.692982102 0.492235917 0.820324769 0.852748684 0.63022157 0.702158395 0.76889328 0.637970805 0.954706947 1 10.19322651 -9.102630863 0.855961192 1.00167901 0.7033153 0.554301268 0.098767766 0.361029024 0.476241022 0.067478668 0.019587627 7.90E-10 9.102630863 -0.29836371 (ac)ADGS(ph)LTGGGLEAAAMAPER ddPTM_HeLa_Curcumin_4h_R1 2 ADGSLTGGGLEAAAMAPER 19 0 Q8NEM2 Q8NEM2 SHCBP1 SHC SH2 domain-binding protein 1 1 0 ADGS(0.999)LT(0.001)GGGLEAAAMAPER;ADGS(0.928)LT(0.072)GGGLEAAAMAPER ; 116.84 3.37E-06 6129400 1215.12 1120.8 841.12 1269.24 1064.7 928.81 761.93 699.02 1137.79 1140.09 TRUE FALSE FALSE 1118.94197 1217.676958 872.2926471 1263.988221 1052.004148 736.1643362 783.3077052 912.1479801 1012.977284 1179.708043 0.948490584 1.03218501 0.739414004 1.071441556 0.891749577 0.624022478 0.663984373 0.773198069 0.858667778 1 10.20421415 -5.400139561 4.564855247 0.966621945 0.686568978 0.576303596 0.096322405 0.095536071 3.130744353 0.012091201 0.027761333 3.98E-06 5.400139561 -0.280052967 (ac)ADHNPDSDST(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 ADHNPDSDSTPR 12 0 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2;H3BQ71 Q96BT3 CENPT Centromere protein T 1 0 ADHNPDS(0.173)DS(0.086)T(0.741)PR;ADHNPDS(0.002)DS(0.093)T(0.905)PR ; 103.14 0.00020398 7439700 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)ADHS(ph)FS(ph)DGVPSDSVEAAK ddPTM_HeLa_Curcumin_4h_R1 3 ADHSFSDGVPSDSVEAAK 18 0 C9J6D1;Q99733;Q99733-2;E9PNJ7;E9PKT8;C9JZI7;E9PS34;E9PNW0;E9PJJ2;E9PKI2;E9PP22;C9J1B1 C9J6D1 NAP1L4 Nucleosome assembly protein 1-like 4 2 0 ADHS(1)FS(0.999)DGVPS(0.001)DSVEAAK;ADHS(0.998)FS(0.992)DGVPS(0.006)DS(0.005)VEAAK;ADHS(1)FS(0.998)DGVPS(0.001)DS(0.001)VEAAK ;; 90.453 0.00014473 37049400 2745.15 2408.63 2145.5 2494.36 2317.61 3494.97 2117.42 1060.7 3003.9 2686.01 TRUE FALSE FALSE 2527.868481 2616.821245 2225.014117 2484.038999 2289.974014 2770.073826 2176.829106 1384.102547 2674.379685 2779.348648 0.909518309 0.941523204 0.800552359 0.893748613 0.823924705 0.996662951 0.78321556 0.497995294 0.962232532 1 11.44053111 -4.350430974 2.533589468 0.932181788 0.446993423 0.788020013 0.065231781 0.143333373 1.308084727 0.010228572 0.135443546 4.46E-05 4.350430974 -0.485188365 (ac)ADHS(ph)FSDGVPSDSVEAAK ddPTM_HeLa_Curcumin_4h_R1 4 ADHSFSDGVPSDSVEAAK 18 0 C9J6D1;Q99733;Q99733-2;E9PNJ7;E9PKT8;C9JZI7;E9PS34;E9PNW0;E9PJJ2;E9PKI2;E9PP22;C9J1B1 C9J6D1 NAP1L4 Nucleosome assembly protein 1-like 4 1 0 ADHS(0.994)FS(0.006)DGVPSDSVEAAK;ADHS(1)FSDGVPSDSVEAAK;ADHS(0.985)FS(0.015)DGVPSDSVEAAK;ADHS(0.998)FS(0.002)DGVPSDSVEAAK ;;; 158.04 1.53E-96 719564000 10147.8 10079.4 8549.1 8707.54 10813.72 15888.1 9549.9 4335.34 11218.1 10417.6 TRUE FALSE FALSE 9344.590922 10950.61842 8865.937167 8671.510507 10684.77345 12592.72896 9817.844492 5657.165209 9987.502496 10779.61082 0.866876465 1.015863986 0.822472843 0.804436324 0.991202152 1.16819885 0.910779123 0.524802361 0.92651791 1 13.39601747 -1 0.019573923 1.608119153 2.29E-05 0.079127275 0.155152841 7070.891181 10.77776049 331.729578 588.4343919 0.1 1 -1.608096253 (ac)ADHSFS(ph)DGVPSDSVEAAK ddPTM_HeLa_Curcumin_4h_R1 1 ADHSFSDGVPSDSVEAAK 18 0 C9J6D1;Q99733;Q99733-2;E9PNJ7;E9PKT8;C9JZI7;E9PS34;E9PNW0;E9PJJ2;E9PKI2;E9PP22;C9J1B1 C9J6D1 NAP1L4 Nucleosome assembly protein 1-like 4 1 0 ADHS(0.006)FS(0.993)DGVPSDS(0.001)VEAAK 100.04 2.10E-07 190200000 1719.6 1628.6 1492.4 1632.7 1744.7 2409 1361.2 1324.9 2162.6 1871.6 TRUE FALSE FALSE 1583.491845 1769.368927 1547.709657 1625.94432 1723.895592 1909.346245 1399.391609 1728.855911 1925.368191 1936.637961 0.817649905 0.913629167 0.799173458 0.839570613 0.890148612 0.985907683 0.722588133 0.892709916 0.994180755 1 10.91933856 -9.378648021 0.97685815 1.00455023 0.854749097 0.403463607 0.067586356 0.470121766 0.76278317 0.051582567 0.011764652 4.18E-10 9.378648021 -0.149801133 (ac)ADHSFSDGVPS(ph)DSVEAAK ddPTM_HeLa_Curcumin_4h_R1 1 ADHSFSDGVPSDSVEAAK 18 0 C9J6D1;Q99733;Q99733-2;E9PNJ7;E9PKT8;C9JZI7;E9PS34;E9PNW0;E9PJJ2;E9PKI2;E9PP22;C9J1B1 C9J6D1 NAP1L4 Nucleosome assembly protein 1-like 4 1 0 ADHS(0.015)FS(0.029)DGVPS(0.606)DS(0.35)VEAAK 127.83 1.61E-53 17567000 1753.6 1927.7 1564.7 1828.7 1647.1 2349 1518.4 1251 2225.4 1813.5 TRUE FALSE FALSE 1614.80071 2094.321798 1622.689158 1821.133324 1627.459408 1861.790921 1561.002217 1632.424141 1981.279188 1876.51899 0.860529906 1.116067468 0.864733673 0.970484889 0.867275747 0.992151388 0.831860602 0.869921461 1.055826879 1 10.87384317 -4.748951734 24.99775148 0.941789993 0.850890995 0.193236843 0.083031741 296.201227 592924.3083 0.010631817 0.039229648 1.78E-05 4.748951734 -0.090898998 (ac)ADKEAAFDDAVEER ddPTM_HeLa_Curcumin_4h_R1 1 ADKEAAFDDAVEER 14 1 Q09028-3;Q09028;E9PNS2;E9PIC4;E9PNS6 Q09028-3 RBBP4 Histone-binding protein RBBP4 0 0 84.169 0.0010835 60118000 4151.2 2716 3455.3 3507.5 3388.1 4268.7 3190.6 3327 3965.3 3082.9 FALSE FALSE TRUE 3822.62814 2950.758938 3583.356458 3492.986894 3347.69912 3383.323502 3280.119649 4341.386984 3530.316511 3190.030546 1.198304557 0.924993945 1.123298478 1.094969733 1.049425412 1.060592823 1.028240828 1.360923327 1.106671695 1 11.63935452 (ac)ADKPDMGEIAS(ph)FDK ddPTM_HeLa_Curcumin_4h_R1 2 ADKPDMGEIASFDK 14 1 P63313 P63313 TMSB10 Thymosin beta-10 1 0 ADKPDMGEIAS(1)FDK;ADKPDMGEIAS(1)FDK ; 64.798 0.0018341 9522400 2472.95 2141.29 2847.77 2857.15 2565.16 3481.73 2815.48 2542.68 2559.08 2183.8 TRUE FALSE FALSE 2277.213398 2326.373566 2953.310861 2845.32787 2534.572142 2759.579951 2894.474791 3317.931427 2278.355327 2259.686887 1.007756168 1.029511469 1.30695579 1.259169085 1.121647497 1.22122227 1.280918523 1.468314679 1.008261516 1 11.14190716 -1 0.194884766 0.951280211 3.153910905 0.714660681 0.08172691 20.76313357 0.235165695 0.090074628 13.95906647 0.1 1 2.202630694 (ac)ADKPDMGEIASFDK ddPTM_HeLa_Curcumin_4h_R1 1 ADKPDMGEIASFDK 14 1 P63313 P63313 TMSB10 Thymosin beta-10 0 0 103.08 2.25E-08 2698200 1880.9 1407.2 1440.7 1725.1 1672.8 1551.1 1129 1263 1760.1 1499.4 FALSE FALSE TRUE 1732.02478 1528.832098 1494.093609 1717.961993 1652.852953 1229.384376 1160.676701 1648.082886 1567.021434 1551.504038 1.116352093 0.985387121 0.962996919 1.107288122 1.06532301 0.792382324 0.748097764 1.062248531 1.010001518 1 10.59945174 -5.270010844 24.80488841 1.048326837 0.855628361 0.413053364 0.090384981 345.1370773 998790.1207 0.012829789 0.029119433 5.37E-06 5.270010844 -0.192698476 RFEK(ac)PLEEK ddPTM_HeLa_Curcumin_4h_R1 2 RFEKPLEEK 9 2 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 1 ; RFEK(1)PLEEK;RFEK(1)PLEEK 104.07 0.0012468 11431400 4192.5 5250.6 4393.1 3935.8 8901 12071.9 8733.1 7412.7 8154.1 4106.1 FALSE TRUE FALSE 3860.659201 5704.438468 4555.912151 3919.514702 8794.861388 9568.051862 8978.127282 9672.798106 7259.615631 4248.786669 0.90864981 1.342604115 1.072285456 0.922502118 2.069970105 2.251949228 2.113103806 2.276602442 1.708632651 1 12.05283519 -5.730597956 5.725883807 0.994625375 2.190654549 0.775718738 0.259796027 0.02786129 2.500419254 0.019959416 0.039562315 1.86E-06 5.730597956 1.196029174 (ac)ADLDS(ph)PPKLSGVQQPSEGVGGGR ddPTM_HeLa_Curcumin_4h_R1 1 ADLDSPPKLSGVQQPSEGVGGGR 23 1 E9PRT5;H3BSD2;H3BMV9;A0A6I8PIQ6;Q9H9E3-2;Q9H9E3 E9PRT5 COG4 Conserved oligomeric Golgi complex subunit 4 1 0 ADLDS(0.996)PPKLS(0.004)GVQQPSEGVGGGR 69.255 3.88E-06 8462900 652.91 687.89 600.08 798.8 766.73 653.82 369.82 470.18 892.78 593.06 TRUE FALSE FALSE 601.2314846 747.3481464 622.3194927 795.4947773 757.5872455 518.2103619 380.1961539 613.5357176 794.8442676 613.6687909 0.979732868 1.217836327 1.014096695 1.296293357 1.234521385 0.844446336 0.619546178 0.999783151 1.295233324 1 9.261316404 -5.02536047 22.56327858 1.046863549 0.790247633 0.361864732 0.164064145 167.7945587 149288.603 0.02126588 0.054564286 9.43E-06 5.02536047 -0.256615916 (ac)ADLEEQLS(ph)DEEKVR ddPTM_HeLa_Curcumin_4h_R1 2 ADLEEQLSDEEKVR 14 1 C9JUG7;F8W9N7;P47755-2;P47755 C9JUG7 CAPZA2 F-actin-capping protein subunit alpha-2 1 0 ADLEEQLS(1)DEEKVR;ADLEEQLS(1)DEEKVR ; 82.705 0.0043159 57873000 2369.6 2259.88 2217.55 2675.62 2373.34 3149.1 2603.2 2398.51 2716.09 2446.76 TRUE FALSE FALSE 2182.04366 2455.213957 2299.734354 2664.548993 2345.039471 2495.941162 2676.238786 3129.804658 2418.141722 2531.784728 0.861859871 0.969756208 0.90834514 1.052439002 0.926239678 0.98584257 1.057056217 1.236204889 0.95511348 1 11.30593903 -1.000001351 0.724713854 0.93872906 46.10107874 0.752092036 0.049196697 129.9352524 0.583929268 0.009870769 9557.744175 0.099999689 1.000001351 45.16234968 NSDGSYS(ph)VFWQQNQK ddPTM_HeLa_Curcumin_4h_R1 1 NSDGSYSVFWQQNQK 15 0 A0A0G2JMS6;Q6IE36 A0A0G2JMS6 OVOS2 Ovostatin homolog 2 1 0 NSDGS(0.004)Y(0.395)S(0.601)VFWQQNQK 107.03 0.0025438 37545000 914.36 698.4 1045.6 1127.1 1430.4 1691.2 1423.7 1089.5 862.15 654.17 TRUE FALSE FALSE 841.9874412 758.766584 1084.350856 1122.436359 1413.343414 1340.426056 1463.64519 1421.683535 767.574302 676.9023588 1.243883154 1.120939489 1.601930975 1.658195372 2.087957585 1.980235464 2.162269301 2.100278594 1.133951289 1 9.402803934 -6.277477195 0.824665191 1.088036931 2.150943123 0.947716885 0.099279824 0.092692027 0.124345456 0.02054752 0.047167318 5.28E-07 6.277477195 1.062906192 up (ac)ADQLTEEQIAEFK ddPTM_HeLa_Curcumin_4h_R1 1 ADQLTEEQIAEFK 13 0 P0DP25;P0DP24;P0DP23;F8WBR5;M0QZ52;G3V479 P0DP25 CALM2;CALM3;CALM1 0 0 113.47 0.00073583 14928000 5197.7 4560.4 4555.9 4419.5 4573.9 5409.8 4301.8 4558 4555.6 4381.6 FALSE FALSE TRUE 4786.29656 4954.580655 4724.745662 4401.21328 4519.35923 4287.746499 4422.49693 5947.713218 4055.862078 4533.860274 1.055678003 1.09279518 1.042102177 0.970743034 0.996801612 0.945716506 0.975437412 1.311843078 0.894571476 1 12.14652421 -4.256267168 24.95686195 1.018685838 1.311843203 0.719432152 0.057562889 190.4840013 919089.6238 0.006582744 0.073991985 5.54E-05 4.256267168 0.293157365 (ac)ADQLTEEQVTEFK ddPTM_HeLa_Curcumin_4h_R1 2 ADQLTEEQVTEFK 13 0 P27482 P27482 CALML3 Calmodulin-like protein 3 0 0 ; ; 135.55 0.00013241 25615000 12058.3 9308.8 10141.7 10529.7 11191.7 13223.3 10716.1 11612.5 11793 9859.5 FALSE FALSE TRUE 11103.87283 10113.41119 10517.56032 10486.13089 11058.24629 10480.63852 11016.76493 15153.09779 10499.3374 10202.11689 1.088389101 0.991305167 1.03091941 1.027838732 1.083916839 1.027300376 1.079850882 1.485289568 1.02913322 1 13.31658092 -4.259765513 3.901582299 1.03966635 1.528566419 0.953717166 0.029569323 0.044412755 1.347371068 0.005084044 0.061763675 5.50E-05 4.259765513 0.488900069 (ac)ADVLDLHEAGGEDFAMDEDGDES(ph)IHK ddPTM_HeLa_Curcumin_4h_R1 1 ADVLDLHEAGGEDFAMDEDGDESIHK 26 0 Q9Y5S9;Q9Y5S9-2 Q9Y5S9 RBM8A RNA-binding protein 8A 1 0 ADVLDLHEAGGEDFAMDEDGDES(1)IHK 48.865 3.16E-08 5953500 503.93 602.82 512.89 587.53 707.88 783.07 785.34 411.39 600.61 581.89 TRUE FALSE FALSE 464.0434088 654.9250747 531.8981546 585.0989565 699.4389933 620.652455 807.3745268 536.8209172 534.7245857 602.1106342 0.770694591 1.087715509 0.883389405 0.971746592 1.161645308 1.030794707 1.34090727 0.891565248 0.88808361 1 9.233884788 -5.914093332 4.147006018 0.906757333 1.117066629 0.290953494 0.131040647 0.192047414 6.26499196 0.02021457 0.037571242 1.22E-06 5.914093332 0.210309296 (ac)AEAPAS(ph)PAPLSPLEVELDPEFEPQSRPR ddPTM_HeLa_Curcumin_4h_R1 2 AEAPASPAPLSPLEVELDPEFEPQSRPR 28 1 O43524 O43524 FOXO3 Forkhead box protein O3 1 0 AEAPAS(0.645)PAPLS(0.355)PLEVELDPEFEPQSRPR;AEAPAS(0.88)PAPLS(0.12)PLEVELDPEFEPQSRPR ; 103.02 9.88E-11 12987500 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)AEAS(ph)PHPGR ddPTM_HeLa_Curcumin_4h_R1 3 AEASPHPGR 9 0 U3KQF4;K7EIY6;Q9BV68 U3KQF4 RNF126 E3 ubiquitin-protein ligase RNF126 1 0 AEAS(1)PHPGR;AEAS(1)PHPGR;AEAS(1)PHPGR ;; 87.298 0.00108 15907400 239.08 354.71 216.01 360.67 358.63 180.15 341.5 232.77 442.55 489.07 TRUE FALSE FALSE 220.1565657 385.3695518 224.0155206 359.1776431 354.3535715 142.7848593 351.0815709 303.7405015 394.0033722 506.0651461 0.435036017 0.761501864 0.442661429 0.709745862 0.70021335 0.282147191 0.693747779 0.600200397 0.778562553 1 8.983179306 -9.419871952 1.047582818 1.010027336 0.569432505 0.354190487 0.157791724 0.317998395 0.60096985 0.10741756 0.024712703 3.80E-10 9.419871952 -0.440594831 (ac)AEDEPDAKS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 AEDEPDAKSPK 11 1 A0A0A0MSQ2;F8W689;P48382-2;P48382;F8WDU3;F8WFE4;F2Z2G0;F6S3S0;A0A0A0MT34;A0A0A0MSM9;F6X9D6;F6R6G4;F6UE82 A0A0A0MSQ2 RFX5 DNA-binding protein RFX5 1 0 AEDEPDAKS(1)PK 61.235 0.018016 108720000 6487.6 4593.8 5122 5437 4912.9 5322.3 4231.2 3128.3 6696.1 5103.6 TRUE FALSE FALSE 5974.099614 4990.867602 5311.825826 5414.503135 4854.316876 4218.394985 4349.916084 4082.104269 5961.554583 5280.94972 1.13125478 0.945070085 1.005846696 1.025289658 0.919212856 0.798794764 0.823699583 0.77298677 1.128879254 1 12.36658169 -5.527382934 1.049075216 1.053557781 0.775120554 0.800060523 0.054213317 0.204971865 0.415840068 0.010074423 0.038255493 2.97E-06 5.527382934 -0.278437227 (ac)AEEES(ph)DQEAER ddPTM_HeLa_Curcumin_4h_R1 1 AEEESDQEAER 11 0 A0A1B0GWA0 A0A1B0GWA0 1 0 AEEES(1)DQEAER 99.732 0.0065324 1094100 0 0 0 0 0 0 0 121.18 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 158.1272242 0 0 0 (ac)AELGAGGDGHR ddPTM_HeLa_Curcumin_4h_R1 1 AELGAGGDGHR 11 0 Q14244-3;Q14244;Q14244-2 Q14244-3 MAP7 Ensconsin 0 0 43.282 0.012068 416200 151.31 0 0 0 0 0 108.99 0 0 0 FALSE FALSE TRUE 139.3336538 0 0 0 0 0 112.0479661 0 0 0 0 (ac)AENDVDNELLDYEDDEVETAAGGDGAEAPAKK ddPTM_HeLa_Curcumin_4h_R1 4 AENDVDNELLDYEDDEVETAAGGDGAEAPAKK 32 1 Q13838-2;Q13838;Q5STU3;F6U6E2;F6WLT2;F6TRA5;A0A0A0MT12;F6S4E6;A0A0G2JHN7;F6S2B7;F6R6M7 Q13838-2 DDX39B Spliceosome RNA helicase DDX39B 0 0 ;;; ;;; 153.82 1.36E-29 87998700 19910.4 15810.1 16866.8 16399.5 18268.8 22514.8 16737.6 16240.9 19410.9 17116.6 FALSE FALSE TRUE 18334.47083 17176.6546 17491.89845 16331.64321 18050.95649 17844.97669 17207.21201 21192.67565 17281.57283 17711.40058 1.03517905 0.969807809 0.987606732 0.922097784 1.019171602 1.007541815 0.971533106 1.196555606 0.975731578 1 14.11239068 -4.255738526 24.87778069 1.002878753 1.196555695 0.773178298 0.033031509 235.5129292 1027714.702 0.004837281 0.058363413 5.55E-05 4.255738526 0.193676942 (ac)AENGESSGPPRPSR ddPTM_HeLa_Curcumin_4h_R1 1 AENGESSGPPRPSR 14 1 Q9UHD9 Q9UHD9 UBQLN2 Ubiquilin-2 0 0 42.718 0.01509 451840 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 (ac)AENHCELLS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 1 AENHCELLSPAR 12 0 H3BSS5;Q9NXV2 H3BSS5 KCTD5 BTB/POZ domain-containing protein KCTD5 1 0 AENHCELLS(1)PAR 86.288 0.00024758 35794000 271.13 174.4 205.2 222.15 129.91 329.98 110.26 180.29 403.39 260.45 TRUE FALSE FALSE 249.6697744 189.4743589 212.8048925 221.2308022 128.3609081 261.5384284 113.3535989 235.259591 359.1391262 269.5006181 0.926416333 0.703057233 0.789626733 0.820891632 0.476291702 0.970455764 0.420606081 0.872946388 1.332609657 1 8.074144772 -7.290630669 0.914791263 0.984287636 0.697366339 0.390420236 0.194862112 0.363664861 0.609230298 0.032878413 0.038500051 5.12E-08 7.290630669 -0.286921297 (ac)AENVVEPGPPSAK(ac)RPK ddPTM_HeLa_Curcumin_4h_R1 2 AENVVEPGPPSAKRPK 16 2 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 0 1 ; AENVVEPGPPSAK(1)RPK;AENVVEPGPPSAK(1)RPK 153.74 3.91E-09 85352000 4770.2 4126.4 4698.6 4588.2 4099.9 6006.6 4130.9 4364.4 4444.2 4398.7 FALSE TRUE FALSE 4392.633637 4483.067629 4872.734249 4569.215244 4051.01137 4760.763452 4246.801936 5695.085469 3956.682379 4551.554498 0.965084267 0.984953082 1.070564848 1.003880157 0.890028093 1.045964286 0.93304429 1.251239653 0.869303527 1 12.15214364 -4.25442154 24.97159191 0.985870192 1.251239777 0.645764882 0.061078202 304.0050137 1081714.248 0.006255392 0.083393464 5.57E-05 4.25442154 0.265369585 (ac)AEPPS(ph)PVHCVAAAAPTATVSEKEPFGK ddPTM_HeLa_Curcumin_4h_R1 1 AEPPSPVHCVAAAAPTATVSEKEPFGK 27 1 Q6PCB5 Q6PCB5 RSBN1L Round spermatid basic protein 1-like protein 1 0 AEPPS(1)PVHCVAAAAPTATVSEKEPFGK 113.89 6.57E-08 7970300 1556.4 1175.2 1263.7 1131.5 1279.2 958.09 758.99 849.91 1478.3 1254.2 TRUE FALSE FALSE 1433.209298 1276.779051 1310.533834 1126.818153 1263.946375 759.3713341 780.2852167 1109.043646 1316.134189 1297.783357 1.104351732 0.983815245 1.009824812 0.86826368 0.973927096 0.585129506 0.601244586 0.854567629 1.014140135 1 10.34183385 -5.643286023 1.304094045 1.041964193 0.675587237 0.661718414 0.097463683 0.178224515 0.595516101 0.015226396 0.0442397 2.27E-06 5.643286023 -0.366376957 (ac)AEQDVENDLLDYDEEEEPQAPQESTPAPPK ddPTM_HeLa_Curcumin_4h_R1 1 AEQDVENDLLDYDEEEEPQAPQESTPAPPK 30 0 K7ENP6;K7EL56;K7EIL8;K7EN69;K7EQN7;O00148-3;O00148-2;O00148 K7ENP6 DDX39A ATP-dependent RNA helicase DDX39A 0 0 72.566 6.31E-11 5241600 11002 9693.9 10274 10762 11169 12668 10342 8769 10250 9498.6 FALSE FALSE TRUE 10131.18009 10531.79752 10654.76348 10717.4697 11035.81697 10040.514 10632.16869 11442.62773 9125.600644 9828.675643 1.030777742 1.071537805 1.084048743 1.090428669 1.122818309 1.021553093 1.081749879 1.164208501 0.928466965 1 13.26278132 -7.332188369 0.874904815 1.007251561 1.094842391 0.560619773 0.041999799 0.288456183 0.447075098 0.007990772 0.009135401 4.65E-08 7.332188369 0.08759083 (ac)AEQLS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 1 AEQLSPGK 8 0 O15541 O15541 RNF113A RING finger protein 113A 1 0 AEQLS(1)PGK 91.867 0.015061 26638000 11087 10270 10851 10353 11888 13073 11977 10045 9946.4 8888.1 TRUE FALSE FALSE 10209.45225 11157.69304 11253.14761 10310.16203 11746.24336 10361.51244 12313.04239 13107.67426 8855.304805 9196.960813 1.110089785 1.213193496 1.223572421 1.121040117 1.277187497 1.126623528 1.338816445 1.425218018 0.962851205 1 13.16694148 -1 0.123795832 0.919253439 2.377396216 0.757203141 0.067663392 31.31606608 0.264706865 0.262603865 7.941235392 0.1 1 1.458142777 (ac)AES(ph)DWDTVTVLR ddPTM_HeLa_Curcumin_4h_R1 1 AESDWDTVTVLR 12 0 O60869-2;O60869-3;O60869 O60869-2 EDF1 Endothelial differentiation-related factor 1 1 0 AES(0.999)DWDT(0.001)VTVLR 90.793 0.0028372 773860 254.42 247.98 289.32 265.54 344.9 243.29 198.71 284.81 412.82 298.21 TRUE FALSE FALSE 234.2823885 269.4142862 300.0424537 264.4412658 340.7872928 192.8289116 204.2852678 371.6472579 367.5346788 308.5727753 0.759245168 0.873098043 0.97235556 0.856981844 1.104398444 0.624905782 0.662032701 1.204407153 1.191079409 1 8.269466971 -9.646063168 1.495244305 0.999619834 0.857837341 0.122890251 0.183265862 0.838408612 3.384612622 0.116516324 0.026677529 2.26E-10 9.646063168 -0.141782493 (ac)AES(ph)SESFTMASSPAQRR ddPTM_HeLa_Curcumin_4h_R1 1 AESSESFTMASSPAQRR 17 1 P49736;F8WDM3 P49736 MCM2 DNA replication licensing factor MCM2 1 0 AES(0.456)S(0.456)ES(0.085)FT(0.001)MASSPAQRR 63.32 0.019154 46874000 242.21 201.77 157.32 204.07 185.54 221.74 234.05 178.51 278.39 227.02 TRUE FALSE FALSE 223.0388229 219.2100997 163.1504176 203.2256124 183.3275567 175.7486245 240.6168131 232.9368772 247.8513135 234.9089281 0.949469331 0.933170576 0.694526253 0.865125111 0.780419706 0.748156428 1.024298289 0.991605041 1.055095332 1 7.875957736 -6.987397877 24.97760447 0.974305762 0.848253695 0.310974178 0.098935832 233.4837434 462766.7349 0.016015018 0.021040741 1.03E-07 6.987397877 -0.126052067 (ac)AESSESFTMAS(ph)SPAQR ddPTM_HeLa_Curcumin_4h_R1 1 AESSESFTMASSPAQR 16 0 P49736;F8WDM3 P49736 MCM2 DNA replication licensing factor MCM2 1 0 AES(0.02)S(0.028)ESFTMAS(0.943)S(0.008)PAQR 89.466 0.0046427 42494000 204.06 191.18 127.4 149.16 202.03 213.22 145.17 160.07 220.78 218.7 TRUE FALSE FALSE 187.9084357 207.7047473 132.1215561 148.5428154 199.6209242 168.9957685 149.2430795 208.8746061 196.5609864 226.2998087 0.830351721 0.917829973 0.583834148 0.656398325 0.882108232 0.746778221 0.659492734 0.922999482 0.868586622 1 7.822091555 -8.290088794 0.587624343 0.994248974 0.751273176 0.235093554 0.114312629 0.552041709 0.417163231 0.05997839 0.029886427 5.13E-09 8.290088794 -0.242975798 (ac)AESSESFTMASS(ph)PAQR ddPTM_HeLa_Curcumin_4h_R1 3 AESSESFTMASSPAQR 16 0 P49736;F8WDM3 P49736 MCM2 DNA replication licensing factor MCM2 1 0 AESSESFTMAS(0.062)S(0.938)PAQR;AESSESFTMAS(0.004)S(0.996)PAQR;AESSESFTMAS(0.021)S(0.979)PAQR ;; 144.4 5.64E-15 87995000 661.335 820.75 441.831 977.39 717.48 674.888 699.17 698.32 808.7 958.18 TRUE FALSE FALSE 608.9896369 891.6919728 458.2056455 973.3458192 708.9245196 534.9086212 718.7868285 911.2345533 719.9876333 991.4766837 0.61422487 0.899357481 0.462144651 0.981713272 0.715018851 0.53950701 0.724965943 0.919068061 0.72617707 1 9.953435035 -9.455877263 1.129711387 1.00366564 0.718484589 0 0.178701546 0.482075556 1.077527419 0.110281381 0.025920886 3.50E-10 9.455877263 -0.285181051 (ac)AESSESFTMASS(ph)PAQRR ddPTM_HeLa_Curcumin_4h_R1 1 AESSESFTMASSPAQRR 17 1 P49736;F8WDM3 P49736 MCM2 DNA replication licensing factor MCM2 1 0 AESSES(0.003)FT(0.025)MAS(0.061)S(0.91)PAQRR 63.754 6.05E-05 50154000 213.04 0 268.19 0 197.95 281.35 193.03 120.68 307.98 190.87 TRUE FALSE FALSE 196.1776592 0 278.1293573 0 195.5895755 222.9948385 198.4459023 157.4747765 274.1953645 197.5027183 0.993290932 0 1.408230528 0 0.990313335 1.12907225 1.004775549 0.797329666 1.388311852 1 7.625728699 -7.452969898 24.99989901 0.997054444 0.768387745 0.104050751 0.444903411 360.7582634 129009.5412 0.067593061 0.077294086 3.52E-08 7.452969898 -0.228666699 (ac)AETLSGLGDSGAAGAAALS(ph)SASSETGTRR ddPTM_HeLa_Curcumin_4h_R1 1 AETLSGLGDSGAAGAAALSSASSETGTRR 29 1 Q15424-2;Q15424;Q15424-4;Q15424-3;K7ES42 Q15424-2 SAFB Scaffold attachment factor B1 1 0 AETLSGLGDSGAAGAAALS(0.278)S(0.049)AS(0.049)S(0.215)ET(0.131)GT(0.278)RR 52.01 2.41E-08 11436000 230.71 243.56 200 211.49 239.64 282.34 201.97 264.31 257.95 271.68 TRUE FALSE FALSE 212.4490601 264.6122411 207.4121759 210.6149104 236.7824495 223.7795014 207.6367346 344.8969023 229.6535304 281.1208598 0.755721437 0.941275725 0.737804289 0.74919702 0.842279899 0.796025957 0.738603086 1.22686343 0.816920987 1 8.135046699 -4.250583237 24.80712818 0.851418778 1.226863669 0.637359844 0.089294764 943.8191781 2156654.969 0.015670035 0.307801359 5.62E-05 4.250583237 0.375444891 (ac)AETVADTRR ddPTM_HeLa_Curcumin_4h_R1 2 AETVADTRR 9 1 O60493-4;O60493;O60493-2;O60493-3 O60493-4 SNX3 Sorting nexin-3 0 0 ; ; 87.754 1.10E-08 1887700 292.91 0 207.79 201.56 0 169.75 68.855 149.43 0 119.52 FALSE FALSE TRUE 269.7258644 0 215.4908802 200.7259981 0 134.5419365 70.78688599 194.9905191 0 123.6733111 2.1809545 0 1.742420238 1.623034075 0 1.087881737 0.572369943 1.57665803 0 1 6.950390388 (ac)AFAETYPAAS(ph)SLPNGDCGRPR ddPTM_HeLa_Curcumin_4h_R1 1 AFAETYPAASSLPNGDCGRPR 21 1 P30520 P30520 ADSS Adenylosuccinate synthetase isozyme 2 1 0 AFAETYPAAS(0.5)S(0.5)LPNGDCGRPR 60.09 8.96E-05 8721900 217.95 216.9 0 281.47 255.31 292.72 211.09 218.41 261.63 265.15 TRUE FALSE FALSE 200.6990275 235.6478695 0 280.3053517 252.265595 232.0065724 217.0126173 285.0022036 232.9298436 274.3639428 0.731506573 0.858887896 0 1.021655211 0.919456079 0.845616119 0.790966244 1.038774267 0.848981252 1 8.099947083 -4.256633739 22.86810103 0.818707971 1.03877453 0.057462553 0.276787996 406.5217041 1934228.819 0.038187277 0.403079725 5.54E-05 4.256633739 0.220066559 (ac)AFS(ph)QVQCLDDNHVNWR ddPTM_HeLa_Curcumin_4h_R1 2 AFSQVQCLDDNHVNWR 16 0 A6ND36 A6ND36 FAM83G Protein FAM83G 1 0 AFS(1)QVQCLDDNHVNWR;AFS(1)QVQCLDDNHVNWR ; 181.87 9.98E-55 13967000 155.81 119.762 134.7 63.132 118.76 0 115.086 0 110.41 0 TRUE FALSE FALSE 143.4774741 130.1136936 139.6921005 62.87077651 117.3438646 0 118.3150034 0 98.29829923 0 0 (ac)AGEGDQQDAAHNMGNHLPLLPAES(ph)EEEDEMEVEDQDSKEAK ddPTM_HeLa_Curcumin_4h_R1 1 AGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAK 41 1 A0A1W2PPJ5;Q96SW2 A0A1W2PPJ5 CRBN Protein cereblon 1 0 AGEGDQQDAAHNMGNHLPLLPAES(1)EEEDEMEVEDQDSKEAK 58.432 3.62E-15 10101000 714.67 415.44 354.61 552.99 380.73 415.72 584.53 288.6 594.94 861.83 TRUE FALSE FALSE 658.1031154 451.3487824 367.7521585 550.7018739 376.1900434 329.4949859 600.9303386 376.5928114 529.6765705 891.7785284 0.737966989 0.506122056 0.412380593 0.617532107 0.421842455 0.369480735 0.67385603 0.4222941 0.593955286 1 9.800541654 -7.82796883 0.730623504 0.962315999 0.47642163 0.324117506 0.151440981 0.177699665 0.209313358 0.032849754 0.026513277 1.49E-08 7.82796883 -0.485894369 (ac)AGITTIEAVKR ddPTM_HeLa_Curcumin_4h_R1 2 AGITTIEAVKR 11 1 A0A087WWU8;P06753-2;P06753-5;P06753-3;P06753-6;P06753-4;D6R904;Q5VU61 A0A087WWU8 TPM3 Tropomyosin alpha-3 chain 0 0 ; ; 94.85 6.20E-08 12411200 3625.3 3285.7 3309.2 3115.7 3259.7 4302.8 3017.3 3382.2 3941 3430.9 FALSE FALSE TRUE 3338.35368 3569.701267 3431.841863 3102.808059 3220.830206 3410.350777 3101.957317 4413.41721 3508.68216 3550.12352 0.940348599 1.005514667 0.966682383 0.874000029 0.907244548 0.960628766 0.873760392 1.24317286 0.988326784 1 11.79365351 -4.251035499 24.8952926 0.956730626 1.24317303 0.782242354 0.046701535 524.072144 1254019.125 0.006857921 0.127407465 5.61E-05 4.251035499 0.286442404 (ac)AGLNSLEAVKR ddPTM_HeLa_Curcumin_4h_R1 1 AGLNSLEAVKR 11 1 P67936;A0A2R8Y5V9;A0A2R8YGX3;A0A590UK79;A0A590UJB9 P67936 TPM4 Tropomyosin alpha-4 chain 0 0 101.72 0.00065438 9929100 1219.8 921.1 1134.4 1141.4 1317.8 1558.6 1042.5 1226.2 1232.7 1180.6 FALSE FALSE TRUE 1123.251543 1000.71578 1176.441862 1136.677189 1302.086096 1235.328791 1071.749744 1600.062735 1097.475894 1221.625762 0.919472704 0.81916722 0.963013304 0.930462687 1.065863324 1.011217043 0.877314295 1.309781428 0.89837324 1 10.25458668 -4.25351291 24.66278753 0.955689097 1.309781638 0.717016219 0.068740646 344.7178657 1072540.752 0.009532224 0.137585289 5.58E-05 4.25351291 0.354092541 (ac)AGS(ph)PELVVLDPPWDK ddPTM_HeLa_Curcumin_4h_R1 1 AGSPELVVLDPPWDK 15 0 Q5SY74;Q96IY1-2;Q96IY1 Q5SY74 NSL1 Kinetochore-associated protein NSL1 homolog 1 0 AGS(1)PELVVLDPPWDK 62.799 0.00057039 3481900 1696.9 1417.7 1568.1 1750 1679.2 1668.9 1871.7 2356.1 1545.8 1538.8 TRUE FALSE FALSE 1562.588574 1540.239671 1626.215165 1742.758964 1659.176637 1322.751328 1924.214865 3074.464044 1376.229607 1592.273185 0.981357087 0.967321239 1.021316681 1.094510025 1.042017571 0.830731397 1.208470307 1.930864673 0.864317518 1 10.63687216 -4.29844697 3.052086526 0.993977881 2.040456179 0.930437238 0.078287603 0.046537142 0.6660509 0.008686182 0.111767221 5.03E-05 4.29844697 1.046478298 (ac)AGS(ph)YPEGAPAILADKR ddPTM_HeLa_Curcumin_4h_R1 2 AGSYPEGAPAILADKR 16 1 Q6P1Q9;F8WAS9 Q6P1Q9 METTL2B Methyltransferase-like protein 2B 1 0 AGS(0.601)Y(0.399)PEGAPAILADKR;AGS(0.617)Y(0.383)PEGAPAILADKR ; 114.71 0.0017835 6642400 2010.57 1784.75 1629.15 1971.06 2166.69 2314.95 1734.24 1642.99 2345.56 1683.45 TRUE FALSE FALSE 1851.431263 1939.015837 1689.527732 1962.904276 2140.853637 1834.803275 1782.898107 2143.930088 2088.257936 1741.949762 1.062849976 1.113129597 0.969906118 1.126843218 1.228998495 1.053304358 1.02350719 1.230764592 1.198804915 1 10.7664873 -6.228522384 22.44086761 1.033944016 1.127559161 0.048367563 0.087647292 183.8702349 125351.1827 0.01057296 0.017531562 5.91E-07 6.228522384 0.093615145 (ac)AGS(ph)YPEGAPAVLADKR ddPTM_HeLa_Curcumin_4h_R1 1 AGSYPEGAPAVLADKR 16 1 Q96IZ6 Q96IZ6 METTL2A Methyltransferase-like protein 2A 1 0 AGS(0.613)Y(0.387)PEGAPAVLADKR 112.94 0.0016391 2708200 982.12 740.34 847.94 899.64 935.2 1073.1 842.04 556.4 1084.4 826.78 TRUE FALSE FALSE 904.3841657 804.3316907 879.3654023 895.9175281 924.0483508 850.5269637 865.6653762 726.0437986 965.444033 855.5105435 1.057128019 0.940177414 1.02788377 1.047231428 1.08011334 0.99417473 1.011869909 0.848667271 1.12850045 1 9.740641825 -4.199205028 2.768187009 1.024722605 0.798358657 0.55231167 0.049175032 0.285544322 2.52151066 0.005352701 0.156205269 6.32E-05 4.199205028 -0.226363948 (ac)AGTVVLDDVELR ddPTM_HeLa_Curcumin_4h_R1 2 AGTVVLDDVELR 12 0 P25205 P25205 MCM3 DNA replication licensing factor MCM3 0 0 ; ; 84.658 0.0022558 2587000 382.35 55.706 397.98 489.04 251.39 358.24 362.35 178.533 140.14 216.43 FALSE FALSE TRUE 352.086594 60.52097842 412.7294889 487.0164821 248.3923384 283.9369858 372.5165658 232.9668898 124.7669926 223.9509264 1.572159579 0.270242144 1.842946111 2.174657144 1.109137356 1.267853589 1.663384795 1.040258657 0.557117555 1 7.807038824 -9.555481168 1.076241891 0.97817534 1.396098436 0.144061358 0.510766746 1.287671051 2.428210063 0.443243531 0.084072137 2.78E-10 9.555481168 0.417923096 HNS(ph)TTSSTSSGGYR ddPTM_HeLa_Curcumin_4h_R1 3 HNSTTSSTSSGGYR 14 0 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0 A0A0A0MRT6 ABI1 Abl interactor 1 1 0 HNS(0.982)T(0.017)T(0.001)SSTSSGGYR;HNS(0.861)T(0.102)T(0.036)S(0.001)STSSGGYR;HNS(0.741)T(0.243)T(0.015)S(0.001)STSSGGYR ;; 156.72 0.00036726 11669600 1088.25 1072.1 624.56 528.55 1688.8 2939.49 1474.45 1552 1172.03 674.91 TRUE FALSE FALSE 1002.113864 1164.767547 647.706743 526.3630001 1668.662163 2329.806639 1515.819099 2025.197655 1043.461241 698.3630723 1.434946812 1.667853862 0.927464193 0.753709669 2.389390604 3.336096554 2.170531574 2.899920881 1.494152945 1 9.447833465 -5.637507095 5.290690456 1.199420205 2.756168004 0.794643966 0.373518315 0.066613949 2.833751955 0.05341089 0.108253222 2.30E-06 5.637507095 1.556747799 (ac)AHS(ph)PVAVQVPGMQNNIADPEELFTKLER ddPTM_HeLa_Curcumin_4h_R1 1 AHSPVAVQVPGMQNNIADPEELFTKLER 28 1 Q8NBY1;B4E0Y9;Q9P289-3;Q9P289 Q8NBY1 STK26 Serine/threonine-protein kinase 26 1 0 AHS(1)PVAVQVPGMQNNIADPEELFTKLER 44.564 7.78E-08 19010000 460.42 349.7 223.57 355.72 175.89 488.27 447.64 780.54 744.54 529.35 TRUE FALSE FALSE 423.9772712 379.9265098 231.8557009 354.2481249 173.7926266 386.9972981 460.1995736 1018.523053 662.8658247 547.7448731 0.774041515 0.693619472 0.423291412 0.64673928 0.317287546 0.70652838 0.840171394 1.859484411 1.210172577 1 9.097360265 -8.794405557 0.964614865 0.982885113 0.750865397 0.072108469 0.400573071 1.310504221 2.415358127 0.173832743 0.077352481 1.61E-09 8.794405557 -0.232019716 AES(ph)GDSLGSEDRDLLYR ddPTM_HeLa_Curcumin_4h_R1 1 AESGDSLGSEDRDLLYR 17 1 H7C1K5 H7C1K5 ANLN 1 0 AES(0.946)GDS(0.048)LGS(0.006)EDRDLLYR 60.034 0.015248 4093900 282.84 203.8 156.21 397.41 370.23 655.37 504.04 482.1 383.93 270.41 TRUE FALSE FALSE 260.4529155 221.4155639 161.99928 395.7656227 365.8152491 519.4388745 518.1820058 629.0900707 341.8138395 279.8067274 0.930831499 0.791316084 0.578968496 1.414424973 1.307385467 1.856420249 1.851928332 2.248302164 1.221606938 1 8.128286839 -5.350235373 1.117198561 0.930354445 2.131904083 0.831633044 0.206540151 0.14421062 0.320301226 0.029181057 0.127371778 4.46E-06 5.350235373 1.201549638 up (ac)AHS(ph)PVQSGLPGMQNLKADPEELFTK ddPTM_HeLa_Curcumin_4h_R1 2 AHSPVQSGLPGMQNLKADPEELFTK 25 1 B4DR80;Q9Y6E0-2 B4DR80 STK24 1 0 AHS(0.96)PVQS(0.04)GLPGMQNLKADPEELFTK;AHS(0.886)PVQS(0.114)GLPGMQNLKADPEELFTK ; 51.001 6.40E-08 81362000 4222 2486.1 2540.5 2970.5 2179 4444.3 3005.5 4797.6 4208.5 4055.5 TRUE FALSE FALSE 3887.824245 2700.987406 2634.653165 2958.208858 2153.016848 3522.502082 3089.826241 6260.366155 3746.838079 4196.428323 0.9264603 0.64363959 0.627832281 0.704934919 0.513059364 0.839404801 0.736299063 1.491832023 0.892863595 1 12.03494622 -4.254871077 24.51787964 0.853344439 1.491832405 0.595740223 0.165819388 406.8556033 1518639.097 0.028602089 0.363691915 5.56E-05 4.254871077 0.638487967 (ac)AK(ac)HHPDLIFCR ddPTM_HeLa_Curcumin_4h_R1 2 AKHHPDLIFCR 11 1 Q7RTV0 Q7RTV0 PHF5A PHD finger-like domain-containing protein 5A 0 1 ; AK(1)HHPDLIFCR;AK(1)HHPDLIFCR 83.397 4.95E-06 27884000 289.11 178.55 362.26 384.48 328.83 454.46 169.813 421.49 288.91 272.38 FALSE TRUE FALSE 266.2266384 193.9830664 375.6856743 382.8891236 324.908917 360.1998732 174.5774958 550.0003607 257.2172958 281.8451847 0.944584662 0.688261063 1.33295048 1.358508658 1.152792152 1.278006128 0.619409184 1.951427204 0.912619089 1 8.138759109 -6.737119662 24.99268705 0.951682618 1.249454477 0.262179237 0.314967946 282.1609094 289968.173 0.044787541 0.063321767 1.83E-07 6.737119662 0.297771859 (ac)AK(ac)ISSPTETER ddPTM_HeLa_Curcumin_4h_R1 2 AKISSPTETER 11 1 P31949 P31949 S100A11 "Protein S100-A11;Protein S100-A11, N-terminally processed" 0 1 ; AK(1)ISSPTETER;AK(1)ISSPTETER 62.633 2.27E-05 74895000 480.16 537.47 518.16 550.13 419.86 573.81 568.76 490.93 514 428.83 FALSE TRUE FALSE 442.1548293 583.9265119 537.3634654 547.8537078 414.8534437 454.7953378 584.7178749 640.612297 457.615486 443.7318106 0.996446094 1.315944672 1.211009562 1.234650514 0.934919322 1.024932914 1.317728098 1.443692523 1.031288438 1 8.793544172 -1 0.372303084 1.021457675 6.333451191 0.339909679 0.134700523 44.07025535 0.539988442 0.039264667 169.8402155 0.1 1 5.311993516 (ac)AKS(ph)PENSTLEEILGQYQR ddPTM_HeLa_Curcumin_4h_R1 1 AKSPENSTLEEILGQYQR 18 1 Q86SQ7-2;Q86SQ7-3;Q86SQ7-4;Q86SQ7 Q86SQ7-2 SDCCAG8 Serologically defined colon cancer antigen 8 1 0 AKS(1)PENSTLEEILGQYQR 134.18 1.30E-31 8995700 1486.5 1457.5 1085.3 1323.1 1526.8 1760 1170.2 1355.8 1623.8 1390.4 TRUE FALSE FALSE 1368.841956 1583.479806 1125.522173 1317.625363 1508.593907 1394.956161 1203.032663 1769.177179 1445.673203 1438.716297 0.951432857 1.100619913 0.782310019 0.915834043 1.048569416 0.969583902 0.836184775 1.229691485 1.004835495 1 10.49056642 -4.24260779 24.53413547 0.965033584 1.229691785 0.451438897 0.089880441 2287.321315 2979906.258 0.0115613 0.5341076 5.72E-05 4.24260779 0.264658201 (ac)ALDGPEQMELEEGK ddPTM_HeLa_Curcumin_4h_R1 2 ALDGPEQMELEEGK 14 0 P62195;J3QQM1;J3KTQ9;J3QSE0 P62195 PSMC5 26S protease regulatory subunit 8 0 0 ; ; 171.62 0.00011723 5958800 6638.1 5750.8 6197.8 5821.6 6441.9 7965.6 6621 6014.4 6497.4 5845.3 FALSE FALSE TRUE 6112.687381 6247.873527 6427.49592 5797.511762 6365.08455 6313.444769 6806.76744 7848.162873 5784.651476 6048.42374 1.010624858 1.032975498 1.062672887 0.958516138 1.05235427 1.043816545 1.125378732 1.297555067 0.956389917 1 12.5623435 -3.783630429 0.976803561 1.009449466 1.772283323 0.884593879 0.031954854 0.807838453 0.312020619 0.003958944 0.810726083 0.000164577 3.783630429 0.762833856 (ac)ALSVPGYS(ph)PGFR ddPTM_HeLa_Curcumin_4h_R1 1 ALSVPGYSPGFR 12 0 F8WC22;F8WD19;C9J4K5;C9JSP0;F8W8A5;Q9NYP3-2;Q9NYP3-3;Q9NYP3 F8WC22 DONSON Protein downstream neighbor of Son 1 0 ALSVPGYS(1)PGFR 71.268 0.0078395 1843400 164.63 161.69 235.13 399.63 244.43 243.55 176.07 196.51 277.67 161.34 TRUE FALSE FALSE 151.5993618 175.6657631 243.8441246 397.9764369 241.5153319 193.0349846 181.0100503 256.4249944 247.2102957 166.946553 0.90807123 1.052227554 1.460611916 2.383855371 1.446662585 1.156268166 1.084239519 1.535970583 1.480775082 1 7.383242496 -6.78761012 4.464772577 0.958969466 1.515162817 0.183395783 0.367818601 0.166128981 7.667624247 0.056164764 0.076405938 1.63E-07 6.78761012 0.556193351 (ac)AMS(ph)SGGSGGGVPEQEDSVLFR ddPTM_HeLa_Curcumin_4h_R1 1 AMSSGGSGGGVPEQEDSVLFR 21 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 0 AMS(0.333)S(0.333)GGS(0.333)GGGVPEQEDSVLFR 59.68 0.00099579 2871700 360.21 284.04 401.3 434.82 560.82 563.97 380.18 304.68 575.52 494.73 TRUE FALSE FALSE 331.6989984 308.5911519 416.172531 433.0208301 554.1325878 446.9962647 390.8468276 397.5755294 512.3868959 511.9218307 0.647948531 0.602809127 0.812961093 0.845872952 1.082455474 0.873172891 0.763489275 0.776633278 1.000908469 1 8.99977972 -6.132174069 5.101239117 0.807355483 0.876520047 0.036070144 0.144010523 0.767892132 28.86732326 0.026341396 0.044290562 7.38E-07 6.132174069 0.069164564 (ac)AQDQGEKENPMR ddPTM_HeLa_Curcumin_4h_R1 1 AQDQGEKENPMR 12 1 P62913 P62913 RPL11 60S ribosomal protein L11 0 0 78.939 0.0004407 2663200 1312.7 1017.8 1246.4 1188.4 1307.3 1277 1203.3 887.69 1331.7 1068.8 FALSE FALSE TRUE 1208.79841 1105.774097 1292.59268 1183.482716 1291.711301 1012.135805 1237.061359 1158.342595 1185.615842 1105.94072 1.093004704 0.999849338 1.16877212 1.070114061 1.16797517 0.915180883 1.118560278 1.047382173 1.07204285 1 10.11105834 -9.388758391 0.933730398 0.996555702 1.074478375 0 0.07512409 1.016951992 1.468921496 0.05715709 0.01226879 4.09E-10 9.388758391 0.077922673 (ac)AQES(ph)PKNSAAEIPVTSNGEVDDSR ddPTM_HeLa_Curcumin_4h_R1 1 AQESPKNSAAEIPVTSNGEVDDSR 24 1 P53367-3;P53367-2;P53367 P53367-3 ARFIP1 Arfaptin-1 1 0 AQES(0.825)PKNS(0.174)AAEIPVT(0.001)S(0.001)NGEVDDSR 43.073 3.57E-06 10283000 360.04 504.42 502.88 496.19 593.64 505.57 463.46 273.13 526.69 700.33 TRUE FALSE FALSE 331.5424541 548.0198171 521.5171752 494.1368973 586.5612307 400.7090831 476.4634403 356.4060797 468.9134247 724.6664154 0.457510445 0.75623736 0.719665165 0.681881879 0.809422402 0.552956608 0.657493476 0.491820888 0.647074868 1 9.501173224 -9.515452331 1.249902597 1.001306531 0.629626096 0.008198149 0.150743881 0.262895334 0.731066932 0.083719752 0.019858715 3.05E-10 9.515452331 -0.371680434 (ac)AQES(ph)PKNSAAEIPVTSNGEVDDSREHSFNR ddPTM_HeLa_Curcumin_4h_R1 1 AQESPKNSAAEIPVTSNGEVDDSREHSFNR 30 2 P53367-3;P53367-2;P53367 P53367-3 ARFIP1 Arfaptin-1 1 0 AQES(0.724)PKNS(0.276)AAEIPVTSNGEVDDSREHSFNR 52.773 9.30E-09 45707000 2548.8 1863.2 2319.6 2460.3 2352.9 3109.5 2736.1 3497.2 3080.4 2752.5 TRUE FALSE FALSE 2347.059791 2024.246706 2405.566417 2450.11993 2324.843204 2464.554649 2812.867602 4563.480181 2742.487827 2848.14917 0.82406491 0.710723556 0.844606891 0.860249862 0.816264551 0.865317967 0.987612458 1.602261647 0.962901752 1 11.47580899 -4.256545243 3.0603841 0.8817732 1.720663199 0.890698318 0.077307919 0.110599328 1.521452476 0.013549396 0.225275072 5.54E-05 4.256545243 0.838889999 (ac)AQILPIR ddPTM_HeLa_Curcumin_4h_R1 1 AQILPIR 7 0 A0A087WVQ6;Q00610-2;Q00610;J3KS13;J3QL20;J3KSQ2 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 46.351 0.0046087 2030900 0 0 0 0 0 0 68.642 75.65 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 70.56790978 98.71533675 0 0 0 (ac)AQS(ph)SPQLDIQVLHDLR ddPTM_HeLa_Curcumin_4h_R1 1 AQSSPQLDIQVLHDLR 16 0 F6SS63;Q8N5C8-2;Q8N5C8;A0A0A0MQY2 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 0 AQS(0.51)S(0.49)PQLDIQVLHDLR 101.6 0.00097628 2808300 222.49 140.29 194.19 299.14 178.21 181.97 188.09 270.34 196.18 322.79 TRUE FALSE FALSE 204.8796817 152.4160425 201.3868522 297.9022379 176.0849621 144.2273708 193.3672992 352.7654215 174.6595448 334.0069285 0.613399496 0.456325991 0.60294214 0.891904366 0.527189549 0.431809518 0.578932 1.056161988 0.522921921 1 8.383734219 -9.125534705 0.871536978 1.001819645 0.633375057 0 0.233577974 0.525898886 0.717796275 0.123163761 0.035360872 7.49E-10 9.125534705 -0.368444588 (ac)AQSS(ph)PQLDIQVLHDLR ddPTM_HeLa_Curcumin_4h_R1 1 AQSSPQLDIQVLHDLR 16 0 F6SS63;Q8N5C8-2;Q8N5C8;A0A0A0MQY2 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 0 AQS(0.394)S(0.606)PQLDIQVLHDLR 117.37 0.000304 3112800 0 106.6 0 59.319 0 120.94 0 0 60.783 0 TRUE FALSE FALSE 0 115.814029 0 59.0735537 0 95.85568073 0 0 54.11525697 0 0 (ac)AQY(ph)GHPSPLGMAAR ddPTM_HeLa_Curcumin_4h_R1 1 AQYGHPSPLGMAAR 14 0 Q8TF42 Q8TF42 UBASH3B Ubiquitin-associated and SH3 domain-containing protein B 1 0 AQY(0.8)GHPS(0.2)PLGMAAR 70.399 0.0054393 0 377.47 514.14 655.92 648.49 384.57 459.92 448.47 459.66 598.75 497.78 TRUE FALSE FALSE 347.5928512 558.5799706 680.2289722 645.8067202 379.9842539 364.5274076 461.0528612 599.808218 533.068623 515.0778179 0.674835606 1.084457438 1.320633404 1.253804178 0.737722031 0.707713272 0.89511302 1.164500192 1.034928324 1 9.008646601 -7.236654348 24.70623499 0.846450126 1.015646787 0.042840143 0.212549949 1211.436635 1207586.57 0.039787214 0.048717552 5.80E-08 7.236654348 0.169196661 (ac)AS(ph)AVSPANLPAVLLQPR ddPTM_HeLa_Curcumin_4h_R1 1 ASAVSPANLPAVLLQPR 17 0 P51610-2;P51610;A6NEM2;P51610-4;P51610-3 P51610-2 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 0 AS(0.621)AVS(0.379)PANLPAVLLQPR 131.09 1.90E-22 38516000 113.64 0 61.195 0 159.17 0 0 0 0 140.4 TRUE FALSE FALSE 104.6452741 0 63.46294053 0 157.2720017 0 0 0 0 145.2788895 0.720306126 0 0.436835253 0 1.082552339 0 0 0 0 1 7.18268127 -7.420511795 0.298964222 1.131785934 1.16E-10 0 0.462935989 0.939994909 0.282607734 0.380677164 0.374149832 3.80E-08 7.420511795 -1.131785934 (ac)AS(ph)GVAVSDGVIK ddPTM_HeLa_Curcumin_4h_R1 35 ASGVAVSDGVIK 12 0 P23528;E9PP50;E9PS23 P23528 CFL1 Cofilin-1 1 0 AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.993)GVAVS(0.007)DGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.998)GVAVS(0.002)DGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(0.998)GVAVS(0.002)DGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.998)GVAVS(0.002)DGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK;AS(0.992)GVAVS(0.008)DGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(1)GVAVSDGVIK;AS(0.999)GVAVS(0.001)DGVIK ;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;; 104.01 1.83E-21 10862835400 123167.58 122288.28 139039.36 164562.7 137229.01 234663.5 189997.56 48354.45 145146.47 171507.87 TRUE FALSE FALSE 113418.7361 132858.334 144192.281 163881.7832 135592.6437 185991.6449 195328.3802 63097.49921 129224.2654 177467.7557 0.639094891 0.748633652 0.812498476 0.923445403 0.764041012 1.048030636 1.100641519 0.355543456 0.728156306 1 17.4371974 (ac)AS(ph)GVQVADEVCR ddPTM_HeLa_Curcumin_4h_R1 4 ASGVQVADEVCR 12 0 P60981;F6RFD5 P60981 DSTN Destrin 1 0 AS(1)GVQVADEVCR;AS(1)GVQVADEVCR;AS(1)GVQVADEVCR;AS(1)GVQVADEVCR ;;; 114.5 0.00068731 531121500 1095.2 710.67 750.12 790.2 938.43 762.34 758.03 712.73 864.27 843 TRUE FALSE FALSE 1008.513764 772.0971481 777.9201071 786.9303618 927.2398352 604.2220907 779.2982817 930.038096 769.4617433 872.2941873 1.156162427 0.885133891 0.891809344 0.90213872 1.062989813 0.692681551 0.893389287 1.066197746 0.882112657 1 9.768670966 -7.248221314 24.51058075 1.073743369 0.908693446 0.060631875 0.120559838 514.6991696 954419.3976 0.018197073 0.022211733 5.65E-08 7.248221314 -0.165049923 (ac)AS(ph)GVTVNDEVIK ddPTM_HeLa_Curcumin_4h_R1 2 ASGVTVNDEVIK 12 0 Q9Y281;F8WDN3;G3V2U0 Q9Y281 CFL2 Cofilin-2 1 0 AS(1)GVTVNDEVIK;AS(0.999)GVT(0.001)VNDEVIK ; 141.88 3.73E-09 504640000 11602.7 10513.6 13339.4 14108.4 12089.5 23725 17139.9 2047.28 13270.7 12863.2 TRUE FALSE FALSE 10684.33405 11422.34874 13833.7699 14050.02318 11945.34061 18804.16756 17620.79946 2671.486247 11814.93741 13310.19524 0.802718056 0.858165378 1.039336362 1.055583553 0.897457955 1.412764217 1.323857325 0.200709772 0.887660714 1 13.70024411 -6.754099815 24.61389612 0.900585528 1.021763224 0.017568095 0.309290097 440.6907967 1477889.259 0.046909437 0.065561241 1.76E-07 6.754099815 0.121177697 TGVTTAVIQPLSVPVQQVHS(ph)PTSYLCRPDGTTTAYFPPVFTK ddPTM_HeLa_Curcumin_4h_R1 1 TGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTK 42 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;H0Y952;Q8WX93-6;D6R9Z5;D6RBH5;D6RBB1 Q8WX93-3 PALLD Palladin 1 0 TGVTTAVIQPLS(0.041)VPVQQVHS(0.528)PT(0.133)S(0.133)Y(0.123)LCRPDGT(0.013)T(0.013)T(0.011)AY(0.004)FPPVFTK 60.268 3.24E-05 52033000 390.52 394.5 522.44 363.3 296.08 1466.9 989.68 1211.3 588.85 385.54 TRUE FALSE FALSE 359.6099299 428.5988221 541.802086 361.7967609 292.5494394 1162.648405 1017.447757 1580.619794 524.2546282 398.9374863 0.901419251 1.074350837 1.358112748 0.906900889 0.733321509 2.914362386 2.550393964 3.962073879 1.314127266 1 8.640018883 -5.220284113 5.460408291 0.975943294 3.113230219 0.867960944 0.37508579 0.044510438 3.45841226 0.047004609 0.120567059 6.02E-06 5.220284113 2.137286925 up (ac)AS(ph)NPERGEILLTELQGDSR ddPTM_HeLa_Curcumin_4h_R1 1 ASNPERGEILLTELQGDSR 19 1 Q16513-3;Q16513-2;Q16513;B1AL79 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 0 AS(0.946)NPERGEILLT(0.054)ELQGDSR 53.3 0.0052144 5775200 0 0 0 0 0 70.806 0 0 155.19 0 TRUE FALSE FALSE 0 0 0 0 0 56.12003745 0 0 138.1660453 0 0 (ac)AS(ph)PGIEVELLGK ddPTM_HeLa_Curcumin_4h_R1 1 ASPGIEVELLGK 12 0 Q8TCY9 Q8TCY9 URGCP Up-regulator of cell proliferation 1 0 AS(1)PGIEVELLGK 83.647 0.00012407 3623100 2784.5 2168.6 3053.1 2310.4 2626.2 3228.4 2295.4 2343.2 2902.8 2562.4 TRUE FALSE FALSE 2564.103887 2356.044121 3166.250572 2300.840177 2594.88428 2558.793448 2359.802746 3057.630893 2584.370102 2651.443209 0.967059705 0.888589321 1.194161188 0.867768983 0.978668625 0.965056856 0.890006898 1.15319494 0.97470317 1 11.37256213 -4.241403977 23.73017468 0.977567923 1.153195273 0.283268629 0.086794093 2257.909898 2674212.792 0.010669354 0.530583583 5.74E-05 4.241403977 0.17562735 (ac)AS(ph)PPESDGFSDVRK ddPTM_HeLa_Curcumin_4h_R1 4 ASPPESDGFSDVRK 14 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 0 AS(1)PPESDGFSDVRK;AS(1)PPESDGFSDVRK;AS(0.993)PPES(0.007)DGFSDVRK;AS(1)PPESDGFSDVRK ;;; 145.99 0.000683 119731000 9041.3 7262.4 7525.3 7941.4 7128.2 8223.8 6485.2 3243.72 8996.6 7304.3 TRUE FALSE FALSE 8325.671565 7890.129495 7804.194238 7908.540591 7043.200871 6518.091179 6667.157258 4232.715296 8009.695488 7558.123881 1.101552673 1.043926988 1.032557068 1.046362922 0.931871584 0.862395388 0.882118018 0.560021953 1.059746521 1 12.88381245 -3.79534408 0.67127216 1.048495663 1.92E-18 0.905581102 0.046304866 1.208360889 0.245606789 0.009025109 1.116036811 0.000160198 3.79534408 -1.048495663 (ac)AS(ph)PSLERPEK ddPTM_HeLa_Curcumin_4h_R1 2 ASPSLERPEK 10 1 Q13601-2;Q13601 Q13601-2 KRR1 KRR1 small subunit processome component homolog 1 0 AS(0.965)PS(0.035)LERPEK;AS(0.978)PS(0.022)LERPEK ; 60.91 0.0074798 542670000 6626.6 5386.1 5275.7 6467.6 6029.6 7110.2 5662.9 4530.3 7335.5 5380.4 TRUE FALSE FALSE 6102.097618 5851.650484 5471.222083 6440.838785 5957.700958 5635.464372 5821.785733 5911.567615 6530.814003 5567.3685 1.096047014 1.051062182 0.982730366 1.156891049 1.070110764 1.012231249 1.045697933 1.061824382 1.173052224 1 12.44277986 -9.551463978 1.318856069 0.999985123 1.063024738 0 0.069510684 0.555238921 1.729631976 0.031140795 0.007360686 2.81E-10 9.551463978 0.063039615 VYT(ph)HEVVTLWYR ddPTM_HeLa_Curcumin_4h_R1 1 VYTHEVVTLWYR 12 0 A0A087WZZ9;P06493;E5RIU6 A0A087WZZ9 CDK1 Cyclin-dependent kinase 1 1 0 VYT(1)HEVVTLWYR 171.62 0.00038752 55519000 333.03 285.76 273.34 175.93 201.38 635 520.3 422.37 233.29 217.93 TRUE FALSE FALSE 306.6703241 310.4598211 283.4702209 175.2020483 198.978675 503.2938421 534.8982177 551.1486686 207.6986707 225.5030513 1.35993869 1.376743327 1.257057141 0.776938703 0.882376863 2.231871539 2.372022084 2.444085193 0.921045944 1 7.817003144 -5.20003207 5.836472949 1.149718085 2.370046368 0.890794901 0.202537519 0.058595938 4.108734968 0.032002141 0.082669507 6.31E-06 5.20003207 1.220328283 up (ac)AS(ph)PSSFTYYCPPSSSPVWSEPLYSLRPEHAR ddPTM_HeLa_Curcumin_4h_R1 2 ASPSSFTYYCPPSSSPVWSEPLYSLRPEHAR 31 1 P49356 P49356 FNTB Protein farnesyltransferase subunit beta 1 0 AS(0.329)PS(0.329)S(0.329)FT(0.011)Y(0.002)YCPPSSSPVWSEPLYSLRPEHAR;AS(0.674)PS(0.157)S(0.157)FT(0.009)Y(0.002)Y(0.001)CPPSSSPVWSEPLYSLRPEHAR ; 77.053 7.69E-13 47682000 0 52.456 66.714 64.577 0 0 0 63.101 0 0 TRUE FALSE FALSE 0 56.9900629 69.18647953 64.30979748 0 0 0 82.34020442 0 0 0 (ac)AS(ph)PTDGTDLEASLLSFEK ddPTM_HeLa_Curcumin_4h_R1 1 ASPTDGTDLEASLLSFEK 18 0 G3V5T8 G3V5T8 LIN52 1 0 AS(0.979)PT(0.021)DGTDLEASLLSFEK 151.7 2.11E-67 21992000 956.59 701.87 611.01 802.28 819.65 1232.5 864.03 1034.1 990.03 1100.1 TRUE FALSE FALSE 880.8748921 762.5365153 633.6545681 798.9603779 809.8762091 976.8656069 888.2723564 1349.39233 881.4261859 1138.328393 0.77383196 0.669873931 0.556653574 0.701871606 0.711460958 0.858157991 0.780330493 1.185415683 0.774316262 1 10.1527011 -4.257381722 24.00390322 0.821033981 1.185415932 0.448496736 0.125867657 224.8828959 1330243.588 0.022566377 0.228718296 5.53E-05 4.257381722 0.364381951 (ac)AS(ph)SVGNVADSTEPTKR ddPTM_HeLa_Curcumin_4h_R1 1 ASSVGNVADSTEPTKR 16 1 O15294 O15294 OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 1 0 AS(0.61)S(0.39)VGNVADSTEPTKR 129.82 0.00070442 6681500 2104.5 1674.3 2270.8 2276.7 2329.1 2779.2 2439.3 2223.2 2404 1993.4 TRUE FALSE FALSE 1937.926604 1819.019031 2354.957846 2267.279619 2301.327004 2202.762592 2507.740193 2901.043446 2140.287215 2062.670502 0.93952311 0.881875719 1.141703362 1.09919622 1.115702679 1.067917823 1.215773528 1.406450251 1.037629235 1 11.01029766 -1 0.392059931 0.968519159 7.613649313 0.750958232 0.069983994 20.6836281 0.247121581 0.017765185 106.6976396 0.1 1 6.645130154 EIS(ph)S(ph)SPTSKNR ddPTM_HeLa_Curcumin_4h_R1 1 EISSSPTSKNR 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 EIS(0.996)S(0.599)S(0.291)PT(0.106)S(0.007)KNR 105.03 0.0047213 0 5092.4 2924.4 2184.5 3225.6 1232.7 4108.6 2598.3 2238.8 9651 7353.8 TRUE FALSE FALSE 4689.331167 3177.172105 2265.459492 3212.253322 1218.000858 3256.430047 2671.201305 2921.399814 8592.309446 7609.344003 0.616259584 0.417535612 0.297720735 0.422145893 0.160066473 0.427951482 0.351042259 0.383922689 1.129178736 1 12.89355637 -8.024047119 0.584809608 0.979379705 0.31928122 0.886124803 0.099267271 0.150784904 0.118541282 0.040781398 0.025820472 9.46E-09 8.024047119 -0.660098485 (ac)ASAVS(ph)PANLPAVLLQPR ddPTM_HeLa_Curcumin_4h_R1 1 ASAVSPANLPAVLLQPR 17 0 P51610-2;P51610;A6NEM2;P51610-4;P51610-3 P51610-2 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 0 AS(0.179)AVS(0.821)PANLPAVLLQPR 96.673 0.00032079 27046000 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)ASCAS(ph)IDIEDATQHLR ddPTM_HeLa_Curcumin_4h_R1 2 ASCASIDIEDATQHLR 16 0 Q6P2E9 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 0 AS(0.001)CAS(0.999)IDIEDATQHLR;AS(0.011)CAS(0.989)IDIEDATQHLR ; 123.76 0.00025741 17787600 322.051 244.18 297.79 329.12 206.714 433.07 308.31 329 344.98 277.23 TRUE FALSE FALSE 296.5603235 265.2858312 308.8263594 327.7581886 204.2490706 343.2464003 316.9603488 429.3105855 307.1365571 286.8637219 1.033802119 0.924779995 1.076561223 1.142557123 0.712007323 1.196548654 1.104916114 1.496566323 1.070670614 1 8.164221719 -3.938009232 1.329281237 1.008781803 2.080435285 0.578103447 0.123175198 1.3477669 1.167975875 0.016030532 2.394153474 0.000115343 3.938009232 1.071653482 (ac)ASEAPS(ph)PPRS(ph)PPPPTSPEPELAQLR ddPTM_HeLa_Curcumin_4h_R1 2 ASEAPSPPRSPPPPTSPEPELAQLR 25 1 Q8N302-2;Q8N302-3;Q8N302 Q8N302-2 AGGF1 Angiogenic factor with G patch and FHA domains 1 2 0 AS(0.138)EAPS(0.883)PPRS(0.978)PPPPT(0.001)SPEPELAQLR;AS(0.183)EAPS(0.818)PPRS(0.999)PPPPTSPEPELAQLR ; 115.85 2.08E-08 9332500 202.24 175.95 170.191 120.97 71.061 346.18 205.89 59.37 269.27 219.01 TRUE FALSE FALSE 186.2324906 191.158334 176.4984282 120.4694582 70.21364399 274.3783657 211.6667193 77.47163969 239.7317547 226.6205812 0.821781012 0.843517094 0.778827886 0.531590986 0.30982907 1.210738955 0.934013664 0.341856151 1.057855175 1 7.824135079 -7.962153661 0.581037923 0.985410313 0.700590167 0.202594462 0.254973704 1.039381587 0.812817653 0.118488163 0.079001518 1.09E-08 7.962153661 -0.284820146 (ac)ASEDNRVPS(ph)PPPTGDDGGGGGR ddPTM_HeLa_Curcumin_4h_R1 1 ASEDNRVPSPPPTGDDGGGGGR 22 1 E9PEM5;A0A494C1L5;P50851-2;P50851;A0A494C0R9 E9PEM5 LRBA Lipopolysaccharide-responsive and beige-like anchor protein 1 0 AS(0.186)EDNRVPS(0.807)PPPT(0.007)GDDGGGGGR 66.059 2.19E-05 9401000 0 57.693 0 93.682 0 0 0 0 0 0 TRUE FALSE FALSE 0 62.67972584 0 93.29436871 0 0 0 0 0 0 0 (ac)ASGEHS(ph)PGSGAAR ddPTM_HeLa_Curcumin_4h_R1 3 ASGEHSPGSGAAR 13 0 A6NKB8;Q9H4A4 A6NKB8 RNPEP Aminopeptidase B 1 0 AS(0.007)GEHS(0.991)PGS(0.002)GAAR;AS(0.061)GEHS(0.924)PGS(0.014)GAAR;ASGEHS(0.995)PGS(0.005)GAAR ;; 106.55 1.37E-13 33172300 125.08 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 115.179786 0 0 0 0 0 0 0 0 0 0 (ac)ASGVAVSDGVIK ddPTM_HeLa_Curcumin_4h_R1 3 ASGVAVSDGVIK 12 0 P23528;E9PP50;E9PS23 P23528 CFL1 Cofilin-1 0 0 ;; ;; 106.18 0.00026551 18666900 12770 12070.7 14521.3 17201 14201.4 22915.5 18927.2 4528.5 15615 18011.7 FALSE FALSE TRUE 11759.24103 13114.03752 15059.47215 17129.82682 14032.05758 18162.56699 19458.24629 5909.218803 13902.07357 18637.60523 0.63094163 0.703633184 0.808015406 0.919100207 0.752889516 0.974511841 1.044031465 0.31705891 0.745915228 1 14.18592888 -9.584484528 1.395762589 0.999035099 0.767099916 0 0.207056881 0.606524978 2.133123616 0.129911489 0.030807157 2.60E-10 9.584484528 -0.231935183 (ac)ASLEVSRS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 ASLEVSRSPR 10 1 Q5QPJ9;Q5QPK2;O60762 Q5QPJ9 DPM1 Dolichol-phosphate mannosyltransferase subunit 1 1 0 ASLEVS(0.084)RS(0.916)PR;ASLEVS(0.055)RS(0.945)PR;ASLEVS(0.062)RS(0.938)PR ;; 100.04 2.26E-05 774531700 2146.3 1464.45 1737.61 1791.73 2063.89 2272.51 2046.84 1449.699 2134.31 1935.03 TRUE FALSE FALSE 1976.41809 1591.030533 1802.007355 1784.316296 2039.27946 1801.16581 2104.268822 1891.705552 1900.181533 2002.272148 0.98708764 0.794612527 0.899981232 0.89114574 1.018482658 0.899560937 1.050940464 0.944779436 0.949012618 1 10.96742236 -7.486927853 24.98111282 0.994303434 0.930011439 0.090110517 0.068136072 607.8306591 422365.231 0.011578497 0.012892021 3.26E-08 7.486927853 -0.064291995 (ac)ASPS(ph)RQPPPGGSGLLQGSR ddPTM_HeLa_Curcumin_4h_R1 1 ASPSRQPPPGGSGLLQGSR 19 1 Q96S90 Q96S90 LYSMD1 LysM and putative peptidoglycan-binding domain-containing protein 1 1 0 AS(0.185)PS(0.815)RQPPPGGSGLLQGSR 84.734 1.98E-05 39809000 3548.9 2638 3538 3377.5 3374.8 3494.9 2871.5 1362.4 3378.6 2535 TRUE FALSE FALSE 3268.00082 2866.016965 3669.121392 3363.5248 3334.557714 2770.018344 2952.066562 1777.789488 3007.976033 2623.091061 1.2458587 1.092610549 1.398777742 1.28227527 1.271232159 1.056013032 1.125415204 0.677746005 1.14672955 1 11.35705218 -4.071926508 2.066810614 1.157263099 0.332561522 0.621255177 0.116346509 0.941683585 2.737586346 0.020015626 1.733482742 8.47E-05 4.071926508 -0.824701576 TVTPAS(ph)S(ph)AKTSPAKQQAPPVR ddPTM_HeLa_Curcumin_4h_R1 1 TVTPASSAKTSPAKQQAPPVR 21 2 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 2 0 T(0.102)VT(0.268)PAS(0.732)S(0.76)AKT(0.054)S(0.085)PAKQQAPPVR 50.392 0.013558 17787000 1743.1 1045.2 810.88 1674.5 472.99 1488.6 731.94 878.21 3316.4 2319.3 TRUE FALSE FALSE 1605.131796 1135.542431 840.9319261 1667.571363 467.3499032 1179.84758 752.4762665 1145.972186 2952.599217 2399.895502 0.668834036 0.473163281 0.350403559 0.694851655 0.194737605 0.491624564 0.31354543 0.477509202 1.230303242 1 11.22875587 -8.010134562 0.480191138 1.010949275 0.377991439 0.753347165 0.150748757 0.289302506 0.16075816 0.074611163 0.044444497 9.77E-09 8.010134562 -0.632957836 (ac)AT(ph)SATSPHAPGFPAEGR ddPTM_HeLa_Curcumin_4h_R1 1 ATSATSPHAPGFPAEGR 17 0 Q5VVL2;Q9NUP7-2;Q9NUP7 Q5VVL2 TRMT13 tRNA:m(4)X modification enzyme TRM13 homolog 1 0 AT(0.459)S(0.459)AT(0.055)S(0.027)PHAPGFPAEGR 89.663 0.000123 34917000 429.7 314.09 702.71 504.96 553.06 395.3 508.3 226.69 465.55 539.74 TRUE FALSE FALSE 395.6887916 341.23854 728.7530508 502.8706093 546.4651207 313.3103241 522.56153 295.8067374 414.4803297 558.4959248 0.708490025 0.610995577 1.304849361 0.900401573 0.978458564 0.560989454 0.935658627 0.529648874 0.742136713 1 9.125402944 -5.27042803 24.76947779 0.883715041 0.701454945 0.182939119 0.207208709 869.1732456 2395130.001 0.030148576 0.068367081 5.37E-06 5.27042803 -0.182260096 (ac)ATAAET(ph)S(ph)ASEPEAESK ddPTM_HeLa_Curcumin_4h_R1 1 ATAAETSASEPEAESK 16 0 A0A499FI31;Q15020-4;Q15020;A0A494C0L2;F8W667;Q15020-3;Q15020-2 A0A499FI31 SART3 Squamous cell carcinoma antigen recognized by T-cells 3 2 0 AT(0.274)AAET(0.754)S(0.971)AS(0.001)EPEAESK 80.545 0.00097699 12819000 4551.2 4151 4179.7 4704.6 4467.9 4928.9 2927.7 1847.3 5025.7 4031.2 TRUE FALSE FALSE 4190.967718 4509.793944 4334.603359 4685.133612 4414.623211 3906.59058 3009.843382 2410.533266 4474.393284 4171.2839 1.004718887 1.081152482 1.039153283 1.123187422 1.058336789 0.936543921 0.721562822 0.577887606 1.072665729 1 12.02627579 -4.691787179 2.13342698 1.023702956 0.581636797 0.931118512 0.043675021 0.071704605 0.590846325 0.006942028 0.043266193 2.03E-05 4.691787179 -0.442066159 (ac)ATAAETS(ph)ASEPEAESK ddPTM_HeLa_Curcumin_4h_R1 1 ATAAETSASEPEAESK 16 0 A0A499FI31;Q15020-4;Q15020;A0A494C0L2;F8W667;Q15020-3;Q15020-2 A0A499FI31 SART3 Squamous cell carcinoma antigen recognized by T-cells 3 1 0 ATAAET(0.124)S(0.826)AS(0.049)EPEAESK 86.548 0.00017529 0 1195.1 923.14 1141 964.46 1325.3 1255.9 876.11 579.1 1002.7 811.69 TRUE FALSE FALSE 1100.506574 1002.932108 1183.286464 960.4693201 1309.496663 995.4121831 900.6912887 755.6649242 892.7063186 839.8961671 1.310288839 1.194114401 1.40884851 1.143557213 1.559117322 1.185161002 1.072384092 0.899712314 1.062877 1 9.714067174 -1.199424719 17.54795516 1.18026666 0.019206607 0 0.187315867 0 0 0.026302762 0 0.063179369 1.199424719 -1.161060053 (ac)ATAAETSAS(ph)EPEAESK ddPTM_HeLa_Curcumin_4h_R1 1 ATAAETSASEPEAESK 16 0 A0A499FI31;Q15020-4;Q15020;A0A494C0L2;F8W667;Q15020-3;Q15020-2 A0A499FI31 SART3 Squamous cell carcinoma antigen recognized by T-cells 3 1 0 AT(0.001)AAET(0.04)S(0.056)AS(0.903)EPEAESK 109.07 0.0001935 11830000 1827.9 1360.2 1596.4 1442.6 1363.2 1841.1 1374.5 1329.9 1630.3 1555 TRUE FALSE FALSE 1683.219786 1477.769627 1655.563988 1436.630903 1346.94473 1459.235107 1413.064771 1735.380388 1451.460169 1609.036134 1.046104404 0.918419168 1.0289166 0.892851859 0.837112792 0.906900147 0.878205741 1.078521701 0.9020681 1 10.65198101 -6.67375201 1.418584166 1.0194559 0.915156523 0 0.078694795 0.355949277 1.44714244 0.011859919 0.01828561 2.12E-07 6.67375201 -0.104299377 (ac)ATAEVLNIGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 ATAEVLNIGKK 11 1 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 0 1 ; ATAEVLNIGK(1)K;ATAEVLNIGK(1)K 75.378 9.37E-07 5060800 5220.7 4894.1 4246.9 4162.8 5047.3 6299.1 4762.3 4359.4 5707.2 4171.4 FALSE TRUE FALSE 4807.476086 5317.124196 4404.29385 4145.575437 4987.114244 4992.595655 4895.917321 5688.560992 5081.134439 4316.35584 1.113781223 1.231854924 1.020373207 0.960434123 1.155399237 1.156669153 1.134271015 1.317908255 1.177181546 1 12.07559809 -1 0.522895394 1.059675385 10.01688171 0.330150866 0.084705935 75.53085422 0.682180987 0.015930587 755.2766498 0.1 1 8.957206322 (ac)ATAEVLNIGKK ddPTM_HeLa_Curcumin_4h_R1 1 ATAEVLNIGKK 11 1 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 0 0 67.993 0.0016494 5830500 2483.2 1751.8 2269.7 1967.6 1973.9 2456.6 1654.6 2113.9 2688.1 2366.3 FALSE FALSE TRUE 2286.6521 1903.217786 2353.817079 1959.458593 1950.362532 1947.073468 1701.023623 2758.418379 2393.222155 2448.528749 0.933888197 0.777290357 0.961318947 0.800259582 0.796544673 0.795201392 0.694712539 1.126561565 0.977412316 1 11.25769942 -7.65456755 0.902912268 0.986478663 0.83744908 0.175915448 0.114537914 0.507710657 0.869606172 0.027575291 0.026250902 2.22E-08 7.65456755 -0.149029582 (ac)ATAT(ph)PVPPR ddPTM_HeLa_Curcumin_4h_R1 1 ATATPVPPR 9 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 1 0 AT(0.053)AT(0.947)PVPPR 60.167 0.0048833 13915000 144.38 154.2 170.02 292.38 102.73 167.66 225.83 228.05 276.68 204.57 TRUE FALSE FALSE 132.9521707 167.5283609 176.3210908 291.170209 101.5050118 132.8854261 232.166182 297.5813952 246.3288962 211.6787923 0.628084511 0.791427233 0.83296531 1.375528488 0.479523767 0.6277692 1.096785273 1.405815821 1.163691901 1 7.725732925 -4.499580167 4.017214617 0.82343556 1.366635303 0.294625118 0.255467973 0.176856512 6.167281906 0.034000137 0.192763095 3.17E-05 4.499580167 0.543199744 AGSNEDPILAPS(ph)GTPPPTIPPDETFGGRVPR ddPTM_HeLa_Curcumin_4h_R1 1 AGSNEDPILAPSGTPPPTIPPDETFGGRVPR 31 1 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 "Proline-, glutamic acid- and leucine-rich protein 1" 1 0 AGSNEDPILAPS(0.721)GT(0.25)PPPT(0.029)IPPDETFGGRVPR 114.68 2.87E-12 15535000 3200 1863.5 1920.6 2253.8 945.3 3097.4 1741.2 1444.1 5200.4 4115.5 TRUE FALSE FALSE 2946.716623 2024.572636 1991.779126 2244.474373 934.0279149 2454.964325 1790.053386 1884.399442 4629.929131 4258.513319 0.691959001 0.475417707 0.467717012 0.527055854 0.219331923 0.57648389 0.420347021 0.442501714 1.087217248 1 12.05613415 -7.922910121 0.572086523 0.982985675 0.414573941 0.842499894 0.100858904 0.187537998 0.143166166 0.042025479 0.028827267 1.19E-08 7.922910121 -0.568411734 (ac)ATEEK(ac)KPETEAAR ddPTM_HeLa_Curcumin_4h_R1 2 ATEEKKPETEAAR 13 2 V9GYQ5;V9GZ59;P61964 V9GYQ5 WDR5 WD repeat-containing protein 5 0 1 ; ATEEK(0.993)K(0.007)PETEAAR;ATEEK(0.996)K(0.004)PETEAAR 92.239 5.50E-07 8082100 2378.6 2087.5 2071.9 1829.9 1987.43 2709.3 2119.86 2140.84 2915.2 2179.8 FALSE TRUE FALSE 2190.3313 2267.934198 2148.686437 1822.328359 1963.731195 2147.36064 2179.337566 2793.572261 2595.409853 2255.547888 0.971086144 1.005491486 0.952622841 0.807931576 0.870622701 0.952035047 0.966212058 1.238533784 1.150678231 1 11.1392622 -4.261508744 7.041645697 0.962080662 1.242515402 0.48736687 0.084433072 0.05762518 22.06017941 0.009407957 0.076543848 5.48E-05 4.261508744 0.28043474 (ac)ATEIGS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 1 ATEIGSPPR 9 0 Q9C0J8;B9A053;Q9C0J8-3;Q9C0J8-2 Q9C0J8 WDR33 pre-mRNA 3 end processing protein WDR33 1 0 ATEIGS(1)PPR 119.22 0.00084904 41052000 173.9 65.218 155.29 258.88 0 46.518 0 114.93 152.48 97.973 TRUE FALSE FALSE 160.1356315 70.85515331 161.045184 257.8088232 0 36.86964243 0 149.9716279 135.7533255 101.3775545 1.579596513 0.698923482 1.588568445 2.543056247 0 0.363686445 0 1.479337598 1.339086608 1 6.663594457 -5.717114465 24.99998247 1.337750447 0.420911245 0.390955809 0.597848042 114.3064402 64470.11262 0.085506604 0.171012531 1.92E-06 5.717114465 -0.916839202 (ac)ATES(ph)PATRR ddPTM_HeLa_Curcumin_4h_R1 1 ATESPATRR 9 1 H0YN31;Q01415 H0YN31 GALK2 N-acetylgalactosamine kinase 1 0 AT(0.004)ES(0.755)PAT(0.24)RR 45.081 0.018605 12550000 194.65 241.16 283.94 267.67 221.25 366.45 120.39 185.56 360.33 208.58 TRUE FALSE FALSE 179.2432471 262.0047958 294.4630662 266.5624525 218.6117383 290.4441393 123.7678194 242.1363898 320.8027005 215.8281395 0.830490628 1.213951047 1.364340474 1.235068111 1.012897293 1.345719515 0.573455434 1.121894441 1.486380327 1 7.753739164 -7.262127254 24.99755041 0.919953908 1.120517684 0 0.27894948 87.78457004 3190117.98 0.036754562 0.043379974 5.47E-08 7.262127254 0.200563776 (ac)ATGTGK(ac)HK ddPTM_HeLa_Curcumin_4h_R1 2 ATGTGKHK 8 1 Q9H0E9-4;Q9H0E9-2;B5MCW3;Q9H0E9;F8WDX5;D6RID0;F8WCS7;F8WBH2;C9JV05 Q9H0E9-4 BRD8 Bromodomain-containing protein 8 0 1 ; ATGTGK(1)HK;ATGTGK(1)HK 42.109 0.00056248 8521500 4126.7 7481.9 3528.9 2823.2 2967.8 4302.7 3021.3 3594.7 3381.4 3369.3 FALSE TRUE FALSE 3800.067341 8128.602097 3659.684138 2811.518346 2932.410923 3410.271519 3106.069547 4690.707482 3010.46888 3486.382924 1.089974172 2.331528772 1.049708026 0.806428441 0.841104086 0.978168948 0.890914628 1.345436684 0.863493467 1 11.76751532 -6.52701525 24.99988256 1.166556064 0.957624029 0.096605253 0.409184794 312.5417949 1888909.607 0.06621678 0.093869357 2.97E-07 6.52701525 -0.208932035 (ac)ATNFLAHEK ddPTM_HeLa_Curcumin_4h_R1 1 ATNFLAHEK 9 0 P29692;E9PK01;E9PI39;E9PQ49;E9PL71;P29692-3;P29692-4;E9PQZ1;E9PL12;E9PPR1;E9PK06;E9PK72;E9PKK3;E9PJD0;E9PNW6;E9PMW7;E9PN91 P29692;E9PMW7 EEF1D Elongation factor 1-delta 0 0 58.676 0.0007458 8561000 5565.1 4009.4 4781.4 4896 4761.7 6174.7 4627.7 4708.9 5627.7 4359.5 FALSE FALSE TRUE 5124.616463 4355.95467 4958.60289 4875.741649 4704.919837 4893.997617 4757.540807 6144.621933 5010.35539 4510.992301 1.136028643 0.965631147 1.099226636 1.080857897 1.042989995 1.084904892 1.054655049 1.362144185 1.110699167 1 12.13922911 -4.260595507 24.42661897 1.061782046 1.362144317 0.771710526 0.048653928 20.40389782 590465.394 0.00766977 0.061743604 5.49E-05 4.260595507 0.30036227 (ac)ATS(ph)PQKSPSVPK ddPTM_HeLa_Curcumin_4h_R1 1 ATSPQKSPSVPK 12 1 Q9NVD7-2;Q9NVD7 Q9NVD7-2 PARVA Alpha-parvin 1 0 AT(0.12)S(0.868)PQKS(0.009)PS(0.003)VPK 61.691 0.005987 187840000 4745.8 4047.5 4512 4600.5 4588.2 4083.8 3355.7 2105 4865.1 3995.8 TRUE FALSE FALSE 4370.164922 4397.347865 4679.218689 4581.46435 4533.488712 3236.773846 3449.851911 2746.80481 4331.410702 4134.653753 1.056960312 1.063534731 1.131707507 1.108064816 1.096461514 0.782840363 0.834375045 0.664337324 1.047587286 1 12.0135508 -5.252955749 23.29359624 1.048613431 0.767903239 0.866611372 0.055455105 76.38686492 209734.1212 0.008739315 0.021841912 5.59E-06 5.252955749 -0.280710193 (ac)ATSAT(ph)SPHAPGFPAEGR ddPTM_HeLa_Curcumin_4h_R1 1 ATSATSPHAPGFPAEGR 17 0 Q5VVL2;Q9NUP7-2;Q9NUP7 Q5VVL2 TRMT13 tRNA:m(4)X modification enzyme TRM13 homolog 1 0 AT(0.042)S(0.042)AT(0.801)S(0.115)PHAPGFPAEGR 112.67 0.00025801 31962000 995.05 784.85 541.02 1091.2 769.48 1135.5 746.85 445.16 1411.2 936.12 TRUE FALSE FALSE 916.2907425 852.6889368 561.0706771 1086.684904 760.3044536 899.9845003 767.804601 580.8872347 1256.394891 968.6501003 0.945946057 0.880285809 0.579229463 1.121854943 0.784911346 0.92911207 0.792654232 0.599687374 1.297057514 1 9.919831813 -1.764469687 0.172081911 1.023434169 1.15E-15 0.33248058 0.170909613 43.49179376 0.581690867 0.206826629 10.97046259 0.017200074 1.764469687 -1.023434169 (ac)ATTATMATSGS(ph)AR ddPTM_HeLa_Curcumin_4h_R1 4 ATTATMATSGSAR 13 0 I3L3H2;P38919 I3L3H2 EIF4A3 "Eukaryotic initiation factor 4A-III;Eukaryotic initiation factor 4A-III, N-terminally processed" 1 0 ATTATMAT(0.001)S(0.013)GS(0.987)AR;ATTATMAT(0.004)S(0.012)GS(0.984)AR;ATTATMAT(0.001)S(0.002)GS(0.997)AR;ATTATMATSGS(1)AR ;;; 192.39 7.54E-20 61821000 1539.97 1992.97 1511.99 1766.29 1363.33 1795.59 1387.22 1398.14 1846.14 2354.31 TRUE FALSE FALSE 1418.07975 2165.233446 1568.025679 1758.98156 1347.07318 1423.164394 1426.14166 1824.42645 1643.623061 2436.122097 0.582105368 0.888803336 0.643656441 0.722041626 0.552957991 0.584192556 0.585414689 0.748905998 0.674688294 1 11.25037073 -9.506971436 0.714324404 1.059813884 0.652471712 0 0.140097166 0.541468917 0.37186223 0.142633908 0.019784281 3.11E-10 9.506971436 -0.407342172 (ac)ATVVVEATEPEPSGSIANPAAST(ph)SPSLSHR ddPTM_HeLa_Curcumin_4h_R1 2 ATVVVEATEPEPSGSIANPAASTSPSLSHR 30 0 P46821;D6RA32;D6RCL2;D6RGJ3 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 ATVVVEATEPEPSGSIANPAAS(0.02)T(0.479)S(0.203)PS(0.282)LS(0.016)HR;ATVVVEATEPEPSGS(0.001)IANPAAS(0.064)T(0.455)S(0.455)PS(0.025)LS(0.001)HR ; 98.39 3.83E-13 51312000 0 102.14 67.26 76.716 0 168.76 0 57.889 251.19 289.82 TRUE FALSE FALSE 0 110.9685265 69.75271477 76.39856952 0 133.7572737 0 75.53908961 223.6350854 299.8912234 0 0.370029257 0.232593385 0.254754269 0 0.4460193 0 0.251888297 0.745720675 1 8.228295491 -9.364060591 0.926245125 1.034603173 0.183976477 0.724324325 0.164762938 0.200826558 0.287801845 0.121628718 0.026870598 4.32E-10 9.364060591 -0.850626695 (ac)ATVWDEAEQDGIGEEVLK ddPTM_HeLa_Curcumin_4h_R1 2 ATVWDEAEQDGIGEEVLK 18 0 E9PN50;R4GNH3 E9PN50 PSMC3 0 0 ; ; 236.11 5.24E-132 13045400 6997.5 6038.9 5686.5 6428.4 5763.4 8221.1 6325.5 5966.4 7063.6 6493.4 FALSE FALSE TRUE 6443.640491 6560.875607 5897.246692 6401.800984 5694.675219 6515.951189 6502.976506 7785.527894 6288.740752 6719.045167 0.959011337 0.976459518 0.877691182 0.952784335 0.847542333 0.969773387 0.967842356 1.15872534 0.935957505 1 12.71404051 -4.260436573 5.312784403 0.960765096 1.166926789 0.637073609 0.047191216 0.087470155 8.717556606 0.007047098 0.065454692 5.49E-05 4.260436573 0.206161693 (ac)AVADLALIPDVDIDSDGVFK ddPTM_HeLa_Curcumin_4h_R1 2 AVADLALIPDVDIDSDGVFK 20 0 Q9NRX4-2;Q9NRX4 Q9NRX4-2 PHPT1 14 kDa phosphohistidine phosphatase 0 0 ; ; 109.6 3.80E-05 14453500 7012.2 5676.9 5732.1 5512.2 6246.8 7686 5489.2 6403.5 7401.2 6313.4 FALSE FALSE TRUE 6457.176971 6167.58594 5944.536668 5489.391977 6172.31099 6091.836961 5643.212179 8355.897672 6589.306877 6532.79018 0.988425587 0.944096744 0.909953711 0.840282915 0.944820026 0.932501549 0.863828781 1.279070266 1.008651234 1 12.67348359 -4.250348053 24.77133786 0.961162779 1.279070475 0.754298171 0.057091832 650.1014035 1451904.034 0.009026275 0.181726715 5.62E-05 4.250348053 0.317907697 (ac)AVNVYST(ph)SVTSDNLSR ddPTM_HeLa_Curcumin_4h_R1 1 AVNVYSTSVTSDNLSR 16 0 Q15691 Q15691 MAPRE1 Microtubule-associated protein RP/EB family member 1 1 0 AVNVYS(0.038)T(0.954)S(0.008)VTSDNLSR 149.6 2.56E-17 0 143.6 59.017 131.52 179.32 163.98 187.94 49.194 204.61 250.01 171.8 TRUE FALSE FALSE 132.2339085 64.11816651 136.3942469 178.5780214 162.0246456 148.9591255 50.57425124 266.9946471 222.5845285 177.7700372 0.743848123 0.360680391 0.767251045 1.004545109 0.911428316 0.837931565 0.28449255 1.501910284 1.25209249 1 7.473868371 -9.211111917 1.127025256 0.991493632 0.780869633 0.102683999 0.329728225 1.082630401 2.600761724 0.16225324 0.053138587 6.15E-10 9.211111917 -0.210624 (ac)CDFTEDQTAEFK ddPTM_HeLa_Curcumin_4h_R1 4 CDFTEDQTAEFK 12 0 P60660-2;F8W1R7;G3V1V0;P60660;G3V1Y7 P60660-2 MYL6 Myosin light polypeptide 6 0 0 ;;; ;;; 211.27 3.22E-35 38650500 16839.6 13424.7 14088.1 14561.9 14706 18890.9 13835.9 13328.1 16662.2 13579.6 FALSE FALSE TRUE 15506.72789 14585.07125 14610.21738 14501.64672 14530.64055 14972.7144 14224.09812 17391.77633 14834.39835 14051.49009 1.103564661 1.037973279 1.03976285 1.03203622 1.03409962 1.065560613 1.012283966 1.237717582 1.055717099 1 13.77843551 -13.52285296 0.008971372 3.55E-07 1.986675296 0.150840566 0.059520524 21479.32683 15.58430846 1958.415274 1519.04683 3.00E-14 13.52285296 1.986674941 (ac)CPREGGRAS(ph)T(ph)IHQK ddPTM_HeLa_Curcumin_4h_R1 1 CPREGGRASTIHQK 14 2 Q3KR16-3 Q3KR16-3 2 0 CPREGGRAS(1)T(1)IHQK 76.465 0.0084911 0 1633.3 1717.2 1906.6 1911.7 2049.8 2182 1535.6 1573 2113.7 1802.1 TRUE FALSE FALSE 1504.022582 1865.627116 1977.260273 1903.789892 2025.357474 1729.428604 1578.684803 2052.600459 1881.832398 1864.722841 0.806566289 1.000484938 1.060350756 1.020950594 1.086143972 0.927445391 0.846605602 1.100753642 1.009175389 1 10.8647455 -7.063647717 24.94003976 0.908386215 1.002863987 0.078795253 0.08897937 277.1037154 108581.0705 0.016534483 0.020250533 8.64E-08 7.063647717 0.094477772 (ac)DDDIAALVVDNGS(ph)GMCK ddPTM_HeLa_Curcumin_4h_R1 5 DDDIAALVVDNGSGMCK 17 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5 P60709 ACTB "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed" 1 0 DDDIAALVVDNGS(1)GMCK;DDDIAALVVDNGS(1)GMCK;DDDIAALVVDNGS(1)GMCK;DDDIAALVVDNGS(1)GMCK;DDDIAALVVDNGS(1)GMCK ;;;; 182.91 3.03E-53 25326200 6936.38 5667.92 6059.29 6326.46 6390.96 8443.49 5114.76 4389.39 6837.1 5771.13 TRUE FALSE FALSE 6387.358204 6157.829749 6283.852618 6300.282785 6314.751976 6692.214996 5258.2664 5727.694805 6087.087236 5971.676338 1.069608908 1.031172723 1.052276155 1.055027505 1.057450474 1.120659362 0.880534393 0.959143544 1.019326382 1 12.54392026 -4.750178145 24.99717478 1.042832963 0.919838945 0.676938648 0.035830665 106.5378092 236483.1048 0.005411611 0.019886729 1.78E-05 4.750178145 -0.122994019 (ac)DDDIAALVVDNGSGMCK ddPTM_HeLa_Curcumin_4h_R1 13 DDDIAALVVDNGSGMCK 17 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5 P60709 ACTB "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed" 0 0 ;;;;;;;;;;;; ;;;;;;;;;;;; 234.65 1.40E-288 713880210 41398.2 33877.61 34093.923 35098.861 35150.66 47582.3 34760.94 35867.44 41364.82 35737.35 FALSE FALSE TRUE 38121.48879 36805.83965 35357.47378 34953.63121 34731.51134 37713.19462 35736.23842 46803.25734 36827.20274 36979.22025 1.030889471 0.995311405 0.956144384 0.945223587 0.939216974 1.019848292 0.966387019 1.265663717 0.99588911 1 15.17442718 -4.257318377 24.9827954 0.997969167 1.265663822 0.868673311 0.032494033 126.8671061 769077.0984 0.005277271 0.054191275 5.53E-05 4.257318377 0.267694655 (ac)DIST(ph)RS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 DISTRSK 7 1 Q9ULU4-9;Q9ULU4-11;Q9ULU4-23;Q9ULU4-21;Q9ULU4;A0A087WYS3;A0A087WV57;Q5TH12;Q5TH08;Q5TH07 Q9ULU4-9 ZMYND8 Protein kinase C-binding protein 1 2 0 DIS(0.548)T(0.666)RS(0.786)K 44.753 0.0082063 0 0 140.33 156.79 210.47 0 172.25 0 179.9 0 0 TRUE FALSE FALSE 0 152.4594999 162.6007753 209.5991309 0 136.5234083 0 234.7506818 0 0 0 (ac)EEEIAALVIDNGSGMCK ddPTM_HeLa_Curcumin_4h_R1 3 EEEIAALVIDNGSGMCK 17 0 P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P63261 ACTG1 "Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 0 0 ;; ;; 188.96 1.54E-65 25058500 2884.4 2360.27 2604.55 2315.05 2394.37 3425.47 2333.87 2858.27 2855.86 2498.3 FALSE FALSE TRUE 2656.096696 2564.281222 2701.076914 2305.470937 2365.818702 2714.988909 2399.352111 3729.743365 2542.579303 2585.115739 1.027457555 0.991940586 1.044857247 0.891825036 0.915169354 1.050238822 0.928141079 1.442776162 0.983545636 1 11.33601316 -4.255972782 24.98667131 0.997579722 1.442776353 0.867356199 0.053789129 154.2010274 704798.9543 0.007365919 0.085341868 5.55E-05 4.255972782 0.445196631 (ac)GDREQLLQR ddPTM_HeLa_Curcumin_4h_R1 2 GDREQLLQR 9 1 Q04917;F8WEB6;A2IDB1 Q04917 YWHAH 14-3-3 protein eta 0 0 ; ; 63.306 0.00015682 14985500 415.52 410.82 450.48 387.96 561.76 474.37 439.52 495.23 385.91 404.57 FALSE FALSE TRUE 382.6311535 446.3294502 467.1751851 386.3547243 555.0613789 375.9803147 451.8517483 646.2233472 343.5766385 418.6287774 0.914010632 1.066170016 1.11596529 0.922905317 1.325903542 0.898123433 1.079361412 1.543666805 0.820719112 1 8.709527679 -4.274340699 3.561530188 0.997292753 1.600281892 0.584074995 0.134446874 0.127656584 2.880923455 0.016714676 0.201347225 5.32E-05 4.274340699 0.602989138 (ac)GDS(ph)DDEYDR ddPTM_HeLa_Curcumin_4h_R1 1 GDSDDEYDR 9 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;A0A087X0F4 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 0 GDS(1)DDEYDR 108.43 0.0070397 5105900 0 0 0 0 0 49.976 126.55 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 39.61041425 130.1006524 0 0 0 0 AGSNEDPILAPSGT(ph)PPPTIPPDETFGGRVPR ddPTM_HeLa_Curcumin_4h_R1 1 AGSNEDPILAPSGTPPPTIPPDETFGGRVPR 31 1 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 "Proline-, glutamic acid- and leucine-rich protein 1" 1 0 AGSNEDPILAPS(0.056)GT(0.777)PPPT(0.166)IPPDETFGGRVPR 116.83 4.66E-13 8003600 958.41 528.19 458.49 736.05 318.61 1178.9 487.66 318.63 1492.5 1194 TRUE FALSE FALSE 882.5508372 573.84439 475.4820427 733.0044201 314.8107838 934.3828511 501.3424271 415.7788202 1328.776484 1235.491411 0.714331827 0.464466515 0.384852568 0.593289774 0.254806129 0.756284376 0.405783822 0.336529106 1.075504429 1 10.27086927 -7.887862892 0.693343695 0.96574951 0.445080185 0.71244652 0.143345666 0.236852576 0.254280639 0.047992127 0.036391264 1.29E-08 7.887862892 -0.520669325 (ac)GTRDDEYDYLFK ddPTM_HeLa_Curcumin_4h_R1 2 GTRDDEYDYLFK 12 1 B4DQU5;H3BMH2;H3BSC1;P62491-2;Q15907-2;P62491;Q15907 B4DQU5 RAB11A;RAB11B Ras-related protein Rab-11A;Ras-related protein Rab-11B 0 0 ; ; 85.377 0.0035691 27956000 2761 2503.5 2849.8 3533.9 2807.6 3626 3094.7 2664.9 3308.5 3525.8 FALSE FALSE TRUE 2542.463937 2719.891385 2955.416095 3519.277658 2774.121204 2873.926727 3181.528953 3477.415742 2945.565827 3648.321288 0.696885975 0.745518602 0.810075611 0.964629313 0.760382923 0.787739483 0.872052844 0.953155018 0.807375665 1 11.83301707 -9.575146211 1.382453699 0.999136328 0.806877938 0 0.101245825 0.359276583 1.23982502 0.063245105 0.015084906 2.66E-10 9.575146211 -0.19225839 (ac)IFT(ph)QS(ph)S(ph)EK ddPTM_HeLa_Curcumin_4h_R1 1 IFTQSSEK 8 0 C9JRU6;C9J0B2;C9J8R4;C9JVE2 C9JRU6 DCUN1D1 DCN1-like protein 3 0 IFT(1)QS(1)S(1)EK 46.37 0.013192 3531400 2339.5 2715.4 2789.1 2139.9 1900.9 2742.3 2522.8 1839.4 2567.8 3842 TRUE FALSE FALSE 2154.326106 2950.107076 2892.4665 2131.045661 1878.233009 2173.516068 2593.582978 2400.224592 2286.118764 3975.509214 0.541899412 0.74207024 0.727571323 0.536043447 0.472450926 0.546726457 0.652390131 0.603752743 0.575050551 1 11.95692395 -9.506783691 0.615911508 1.092365004 0.592090436 0 0.155885346 0.533195039 0.254299066 0.156732612 0.019501888 3.11E-10 9.506783691 -0.500274568 (ac)IMASAAKEFK ddPTM_HeLa_Curcumin_4h_R1 1 IMASAAKEFK 10 1 Q9NS56-2 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 0 0 89.752 0.0038316 3294000 1784.1 1452.4 1815.9 1634.1 1741.2 121.96 551.47 418.66 1725 1681.8 FALSE FALSE TRUE 1642.886602 1577.938984 1883.198851 1627.338527 1720.437327 96.66412123 566.942764 546.3075067 1535.771816 1740.242425 0.944056172 0.906735155 1.082147421 0.935121742 0.988619346 0.055546354 0.325783785 0.313926094 0.882504526 1 10.76507258 -5.269703572 24.99841742 0.974132444 0.241155244 0.937430158 0.086497994 83.93476642 253895.0698 0.010895543 0.024749753 5.37E-06 5.269703572 -0.7329772 (ac)KQLIDNILEESDIDR ddPTM_HeLa_Curcumin_4h_R1 1 KQLIDNILEESDIDR 15 1 A0A3B3ISY8 A0A3B3ISY8 0 0 53.013 0.020206 2039800 836.06 944.44 310.14 528.13 490.04 1668.5 503.1 612.18 1077.8 499.46 FALSE FALSE TRUE 769.8849688 1026.073185 321.6340612 525.944738 484.1965931 1322.434292 517.215632 798.8308639 959.5680365 516.8161978 1.489668807 1.985373503 0.622337424 1.01766303 0.936883548 2.558809685 1.000772875 1.54567691 1.856691103 1 9.013507477 -9.331880486 1.084837452 1.002449139 1.391806228 0 0.594913464 1.177487172 2.505495832 0.341865375 0.092528441 4.66E-10 9.331880486 0.389357089 (ac)MAEVNIIYVT(ph)VFILK ddPTM_HeLa_Curcumin_4h_R1 1 MAEVNIIYVTVFILK 15 0 Q8NH85 Q8NH85 OR5R1 Olfactory receptor 5R1 1 0 MAEVNIIY(0.034)VT(0.966)VFILK 62.081 0.008334 0 1033.4 801.61 845.36 981.02 870.65 1438.2 822.01 934.85 1038.6 805.85 TRUE FALSE FALSE 951.6052996 870.8975965 876.6897853 976.9607992 860.2680674 1139.901108 845.0733883 1219.881461 924.6681784 833.8532275 1.141214387 1.044425527 1.05137182 1.171622016 1.031678045 1.367028478 1.013455798 1.462945062 1.108909995 1 9.703649657 -1 0.444284193 1.062176571 7.733223203 0.428113054 0.112710187 52.27154957 0.570737811 0.022775889 317.9413994 0.1 1 6.671046632 (ac)MASEELACK ddPTM_HeLa_Curcumin_4h_R1 1 MASEELACK 9 0 Q9BUP0 Q9BUP0 EFHD1 EF-hand domain-containing protein D1 0 0 41.448 0.012005 2061500 3920.3 2894.2 3321 4783.6 4656.5 234.16 1351.5 1342.6 3893.6 3568.6 FALSE FALSE TRUE 3610.004118 3144.361752 3444.079181 4763.806731 4600.974279 185.5925765 1389.419453 1751.952559 3466.481821 3692.608584 0.97762978 0.851528582 0.932695438 1.290092525 1.245995662 0.05026056 0.376270439 0.474448488 0.938762325 1 11.85042463 -5.262615455 24.99996992 1.01216518 0.307920879 0.806893548 0.16418303 33.81106746 718735.2048 0.023577876 0.055644771 5.46E-06 5.262615455 -0.7042443 (ac)MDDREDLVYQAK ddPTM_HeLa_Curcumin_4h_R1 5 MDDREDLVYQAK 12 1 P62258;B4DJF2;I3L3T1;I3L0W5 P62258 YWHAE 14-3-3 protein epsilon 0 0 ;;;; ;;;; 85.731 2.47E-05 111506900 13770.2 11132 12446.1 12310.3 12149.9 15828.6 11323.8 13298.5 14203.6 12369.9 FALSE FALSE TRUE 12680.27414 12094.20048 12907.36341 12259.36324 12005.02038 12545.56993 11641.51535 17353.15143 12645.50062 12799.7531 0.990665526 0.944877638 1.008407218 0.957781228 0.937910308 0.980141557 0.90951093 1.355741106 0.987948792 1 13.64382836 -4.254696664 24.99994479 0.981283067 1.355741276 0.929447746 0.031827577 150.4614316 557850.8468 0.004527143 0.059182317 5.56E-05 4.254696664 0.37445821 EDS(ph)GTFSLGK ddPTM_HeLa_Curcumin_4h_R1 2 EDSGTFSLGK 10 0 G5E9Q4;O75569 G5E9Q4 PRKRA Interferon-inducible double-stranded RNA-dependent protein kinase activator A 1 0 EDS(0.997)GT(0.002)FSLGK;EDS(0.742)GT(0.069)FS(0.189)LGK ; 158.06 0.00062588 31035900 5161.1 4539.5 5660.9 4165.9 6603.5 12369.5 11932.4 9369.9 5258.3 4759 TRUE FALSE FALSE 4752.593489 4931.874152 5870.697934 4148.66261 6524.757575 9803.926267 12267.19103 12226.73938 4681.477646 4924.374896 0.965116099 1.001522885 1.192171201 0.842474973 1.324992047 1.990897621 2.491116393 2.482901817 0.950674501 1 12.26572488 -5.176912664 1.828603402 0.991369967 2.51479648 0.976952667 0.093287821 0.032184519 0.203364853 0.012629808 0.045207924 6.65E-06 5.176912664 1.523426513 up (ac)MDEET(ph)RHSLECIQANQIFPR ddPTM_HeLa_Curcumin_4h_R1 1 MDEETRHSLECIQANQIFPR 20 1 Q13615-3;Q13615-2;Q13615;C9JLU3 Q13615-3 MTMR3 Myotubularin-related protein 3 1 0 MDEET(0.597)RHS(0.403)LECIQANQIFPR 48.907 0.0016684 7225800 1118 1234.9 1084 1214.3 974.65 1155.8 886.89 1055 1384.7 1380.1 TRUE FALSE FALSE 1029.50912 1341.639253 1124.173994 1209.275548 963.0279353 916.0740514 911.7737465 1376.664643 1232.801874 1428.058372 0.720915293 0.939484883 0.787204512 0.846797002 0.674361745 0.641482218 0.638470923 0.964011465 0.863271347 1 10.47983924 -12.21185766 0.294317755 1.829303526 0.745275024 0.166852223 0.117387256 17.08449374 0.461129008 8.309578756 0.049209655 6.14E-13 12.21185766 -1.084028502 (ac)MDEPS(ph)PLAQPLELNQHSR ddPTM_HeLa_Curcumin_4h_R1 4 MDEPSPLAQPLELNQHSR 18 0 A0A087X2F8;A0A087X126;A0A0C4DGT1;Q13085 A0A087X2F8 ACACA Acetyl-CoA carboxylase 1;Biotin carboxylase 1 0 MDEPS(1)PLAQPLELNQHSR;MDEPS(1)PLAQPLELNQHSR;MDEPS(1)PLAQPLELNQHSR;MDEPS(1)PLAQPLELNQHSR ;;; 191.44 1.52E-41 91978000 74.99 0 276.84 0 123.37 0 0 0 170.32 0 TRUE FALSE FALSE 69.05446237 0 287.0999339 0 121.8988933 0 0 0 151.6363221 0 0 (ac)MDFQHRPGGK ddPTM_HeLa_Curcumin_4h_R1 1 MDFQHRPGGK 10 1 K7EMT0;Q15428 K7EMT0 SF3A2 Splicing factor 3A subunit 2 0 0 44.203 0.019025 3481000 3285.9 2787.5 2368.9 3079.8 2859.7 3483.9 2897.4 2738.3 3351.6 2970 FALSE FALSE TRUE 3025.817548 3028.439079 2456.693518 3067.056604 2825.599945 2761.299868 2978.693246 3573.195064 2983.937865 3073.207279 0.984579715 0.985432743 0.799390765 0.997998614 0.919430318 0.898507526 0.969245799 1.162692503 0.970952362 1 11.58552936 -4.261838838 8.258184195 0.967173949 1.164035428 0.502495795 0.06150169 0.062960706 59.87428115 0.008868794 0.069490156 5.47E-05 4.261838838 0.196861479 (ac)MDGFAGSLDDSISAAS(ph)TSDVQDR ddPTM_HeLa_Curcumin_4h_R1 2 MDGFAGSLDDSISAASTSDVQDR 23 0 B5MBZ0;Q9HC35;Q9HC35-2 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 0 MDGFAGSLDDSISAAS(0.775)T(0.182)S(0.043)DVQDR;MDGFAGSLDDSISAAS(0.931)T(0.053)S(0.015)DVQDR ; 169.43 4.72E-30 7792400 210.428 59.111 168.816 202.16 307.45 282.347 401.99 61.353 61.296 334.32 TRUE FALSE FALSE 193.7724018 64.22029145 175.0724695 201.3235155 303.7838596 223.7850495 413.2687575 80.05924727 54.57198216 345.9375951 0.56013687 0.185641261 0.506081073 0.581964835 0.878146417 0.646894274 1.19463384 0.231426848 0.157750944 1 8.434367998 -9.18650986 1.054173361 0.988822267 0.613411438 0 0.377330543 0.604945467 1.257402775 0.156958315 0.049901324 6.51E-10 9.18650986 -0.375410829 (ac)MDKNELVQK ddPTM_HeLa_Curcumin_4h_R1 1 MDKNELVQK 9 1 P63104;E7EX29;E7ESK7;E5RIR4;E9PD24;E7EVZ2;E5RGE1 P63104 YWHAZ 14-3-3 protein zeta/delta 0 0 77.282 0.007822 11995000 4326.5 3518.1 3747.1 4249.5 3625 4841.9 3377.3 3761.6 4173.7 3730.4 FALSE FALSE TRUE 3984.05296 3822.188888 3885.970822 4231.916695 3581.774243 3837.635361 3472.057948 4908.494524 3715.855552 3860.031122 1.032129751 0.990196391 1.006720075 1.096342636 0.927913307 0.994198036 0.899489625 1.271620453 0.962649117 1 11.91439676 -4.246574109 24.69027846 1.005638104 1.271620676 0.708338538 0.053374249 906.9298574 1506324.597 0.00676 0.199996927 5.67E-05 4.246574109 0.265982572 (ac)MDLAAAAEPGAGS(ph)QHLEVR ddPTM_HeLa_Curcumin_4h_R1 5 MDLAAAAEPGAGSQHLEVR 19 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 1 0 MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR;MDLAAAAEPGAGS(1)QHLEVR ;;;; 157.62 8.79E-19 116393300 183.87 175.93 316.85 316.43 427.642 294.438 113.117 267.934 516.646 250.47 TRUE FALSE FALSE 169.3164955 191.1366053 328.5927397 315.1206965 422.5426485 233.3682398 116.2907586 349.6258432 459.9712264 259.1738139 0.65329322 0.737484248 1.26784699 1.215866263 1.630344679 0.900431399 0.448697948 1.349001421 1.774759647 1 8.01777615 -6.768780761 24.96223475 0.82429326 1.119632113 0 0.425899525 231.5782332 787413.9385 0.052272774 0.069476364 1.70E-07 6.768780761 0.295338852 SAAEMYGSVTEHPS(ph)PSPLLSSSFDLDYDFQR ddPTM_HeLa_Curcumin_4h_R1 1 SAAEMYGSVTEHPSPSPLLSSSFDLDYDFQR 31 0 P07910;G3V2Q1;G3V576;G3V555;G3V575 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 0 SAAEMY(0.002)GS(0.001)VT(0.002)EHPS(0.964)PS(0.03)PLLSSSFDLDYDFQR 86.869 8.29E-07 4524700 667.05 616.36 564.33 436.44 658.84 1644.5 1412 1261.3 958.14 589.67 TRUE FALSE FALSE 614.2522886 669.635412 585.2445662 434.6341269 650.9837633 1303.412163 1451.61692 1645.864564 853.0344391 610.1609886 1.00670528 1.09747333 0.959164183 0.712326968 1.066904924 2.136177479 2.379071994 2.697426736 1.398048146 1 9.253046132 -5.161465485 2.631907294 0.982668042 2.522387312 0.927482031 0.177562992 0.034577062 0.461824615 0.018008547 0.054582179 6.90E-06 5.161465485 1.539719271 up (ac)MDLFGDLPEPERS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 8 MDLFGDLPEPERSPR 15 1 F8SNU6;E9PC05;F8SNU7;Q9H0C8 F8SNU6 ILKAP2;ILKAP;ILKAP3 Integrin-linked kinase-associated serine/threonine phosphatase 2C 1 0 MDLFGDLPEPERS(1)PR;MDLFGDLPEPERS(1)PR;MDLFGDLPEPERS(1)PR;MDLFGDLPEPERS(1)PR;MDLFGDLPEPERS(1)PR;MDLFGDLPEPERS(1)PR;MDLFGDLPEPERS(1)PR;MDLFGDLPEPERS(1)PR ;;;;;;; 124.5 0.00032527 36354900 1467.44 1382.54 1302.942 1752.82 2154.519 2251.545 1489.078 1903.479 2379.347 1365.21 TRUE FALSE FALSE 1351.290576 1502.040597 1351.230177 1745.567295 2128.827768 1784.549187 1530.857521 2483.840985 2118.338587 1412.650946 0.956563672 1.063277947 0.956520916 1.235667806 1.506973661 1.263262657 1.083677129 1.758283596 1.499548486 1 10.46418932 -6.110692246 3.656491518 0.985135531 1.371161311 0.211119914 0.23181589 0.129013436 3.138968418 0.023117049 0.039914164 7.75E-07 6.110692246 0.386025779 (ac)MDRNPS(ph)PPPPGR ddPTM_HeLa_Curcumin_4h_R1 1 MDRNPSPPPPGR 12 1 E9PL53;E9PMD2;J3KND1;E9PRZ1;Q96ER3 E9PL53 SAAL1 Protein SAAL1 1 0 MDRNPS(1)PPPPGR 54.066 0.004625 43191000 2236.3 3185.4 2547.2 2393.6 1231.2 1402.3 1499.8 1572.4 2605.5 3799.5 TRUE FALSE FALSE 2059.294495 3460.731782 2641.601473 2383.695917 1216.518744 1111.447173 1541.880351 2051.817522 2319.683169 3931.532342 0.52378928 0.880250111 0.671901244 0.606301999 0.309426106 0.282700758 0.392183052 0.521887484 0.590020116 1 11.94087601 -13.52287875 0.110275508 2.660629701 0.187997867 0.281113162 0.185595035 51.1721014 0.414365311 19.26749045 0.990182775 3.00E-14 13.52287875 -2.472631833 (ac)MDRS(ph)GFGEIS(ph)SPVIR ddPTM_HeLa_Curcumin_4h_R1 2 MDRSGFGEISSPVIR 15 1 P57740;G3V1T4 P57740 NUP107 Nuclear pore complex protein Nup107 2 0 MDRS(1)GFGEIS(0.85)S(0.15)PVIR;MDRS(1)GFGEIS(0.911)S(0.089)PVIR ; 110.35 0.0008148 4786400 1202.2 765.53 1099.7 1035.71 1272.28 1329.29 934.61 1113.33 1138.6 1079.67 TRUE FALSE FALSE 1107.044601 831.6990021 1140.455849 1031.424506 1257.108892 1053.58027 960.8326412 1452.779192 1013.698429 1117.188452 0.990920197 0.744457214 1.020826743 0.923232338 1.125243364 0.943064053 0.860045268 1.300388658 0.907365652 1 10.12565685 -4.248545456 24.57285345 0.974066571 1.300388923 0.515104858 0.099856467 1038.846984 1979760.676 0.012844108 0.31089724 5.64E-05 4.248545456 0.326322352 (ac)MDSAGQDINLNS(ph)PNK ddPTM_HeLa_Curcumin_4h_R1 4 MDSAGQDINLNSPNK 15 0 O43399;O43399-5;O43399-7;A0A087WYR3;O43399-2;O43399-4;O43399-3;A0A087WZ51 O43399 TPD52L2 Tumor protein D54 1 0 MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK;MDSAGQDINLNS(1)PNK ;;; 198.38 7.19E-63 88278500 17046.7 15215.1 16431.2 15880.9 18579.7 21219.2 18916.1 13833 14934.8 12637.9 TRUE FALSE FALSE 15697.43571 16530.22545 17040.15473 15815.18904 18358.14921 16818.09873 19446.83486 18050.61802 13296.48981 13077.06608 1.200379015 1.26406224 1.303056406 1.209383584 1.403843117 1.286075839 1.487094638 1.380326283 1.016779277 1 13.67475128 -9.75767619 0.056458887 1.52E-07 2.102883896 0.851857477 0.057337986 28.02443105 0.327955773 8.148346251 4.42576501 1.75E-10 9.75767619 2.102883744 (ac)MDT(ph)GLSSQPS(ph)EEDQS(ph)TMPEVK ddPTM_HeLa_Curcumin_4h_R1 1 MDTGLSSQPSEEDQSTMPEVK 21 0 F8W922 F8W922 MVB12B 3 0 MDT(0.752)GLS(0.291)S(0.291)QPS(0.665)EEDQS(0.5)T(0.5)MPEVK 56.819 0.0086331 0 560.53 574.69 409.56 558.61 507.98 483.78 490.82 406.65 552.73 514.93 TRUE FALSE FALSE 516.163459 624.3636428 424.7386539 556.2986198 501.9226703 383.4385747 504.5910882 530.635713 492.0969019 532.8237792 0.968732026 1.171801386 0.797146581 1.044057419 0.942005012 0.719634877 0.94701308 0.995893452 0.923564077 1 9.057514659 -5.518790999 24.99038249 0.988624065 0.883023102 0.132784152 0.110262626 218.5056845 1335829.54 0.014549512 0.029649856 3.03E-06 5.518790999 -0.105600963 (ac)MEDKVTS(ph)PEKAEEAK ddPTM_HeLa_Curcumin_4h_R1 2 MEDKVTSPEKAEEAK 15 2 H3BTD3;P56211-2 H3BTD3 ARPP19 cAMP-regulated phosphoprotein 19 1 0 MEDKVT(0.44)S(0.56)PEKAEEAK;MEDKVT(0.121)S(0.879)PEKAEEAK ; 65.092 0.010322 77870200 5602.2 4952.5 4598.2 5190.5 5419.7 6700.6 4672.7 2602 6222.9 5159.7 TRUE FALSE FALSE 5158.779959 5380.572032 4768.613337 5169.023086 5355.073617 5310.820029 4803.803386 3395.337822 5540.263439 5338.999191 0.966244754 1.007786636 0.893166147 0.968163302 1.003010756 0.994722014 0.899757279 0.635950241 1.037696999 1 12.38235362 -4.274095789 2.536375322 0.979638228 0.567377857 0.890828183 0.036561123 0.098278251 0.807692459 0.004524905 0.08560125 5.32E-05 4.274095789 -0.412260371 (ac)MEDLDQS(ph)PLVSSSDSPPRPQPAFK ddPTM_HeLa_Curcumin_4h_R1 2 MEDLDQSPLVSSSDSPPRPQPAFK 24 1 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4 Q9NQC3-5 RTN4 Reticulon-4 1 0 MEDLDQS(0.681)PLVS(0.157)S(0.157)S(0.004)DSPPRPQPAFK;MEDLDQS(0.886)PLVS(0.055)S(0.055)S(0.002)DS(0.002)PPRPQPAFK ; 88.176 7.66E-06 310080000 7742.3 6681.2 7394.2 8240.8 7071 9856.4 10212.1 7372.5 9842.9 8460.1 TRUE FALSE FALSE 7129.488785 7258.693157 7668.235557 8206.701753 6986.682943 7812.071535 10498.62404 9620.341311 8763.158496 8754.087845 0.814418237 0.829177555 0.875960545 0.937470802 0.79810519 0.892391266 1.199282464 1.098954166 1.001036162 1 13.09574115 -4.768063229 24.99067456 0.894634957 1.149118335 0.677726278 0.070485445 67.2721118 253810.7398 0.011467753 0.035584764 1.71E-05 4.768063229 0.254483379 (ac)MEDLDQSPLVS(ph)SSDSPPRPQPAFK ddPTM_HeLa_Curcumin_4h_R1 1 MEDLDQSPLVSSSDSPPRPQPAFK 24 1 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4 Q9NQC3-5 RTN4 Reticulon-4 1 0 MEDLDQS(0.002)PLVS(0.497)S(0.497)S(0.005)DSPPRPQPAFK 116.85 2.00E-06 96039000 3808.3 3037 3753.2 4588 3541.6 4049.9 4151.1 2741.4 5658.8 4200.7 TRUE FALSE FALSE 3506.869037 3299.504747 3892.296894 4569.016072 3499.368733 3209.905088 4267.568694 3577.24024 5038.043798 4346.674012 0.80679366 0.759087233 0.895465563 1.051152228 0.805068133 0.738473849 0.981800954 0.822983327 1.159057197 1 12.08569619 -9.415012213 1.159134066 0.999504293 0.855953209 0.36023606 0.106175166 0.555323953 1.34180004 0.063232309 0.01622189 3.85E-10 9.415012213 -0.143551084 (ac)MEDLDQSPLVSS(ph)SDSPPRPQPAFK ddPTM_HeLa_Curcumin_4h_R1 1 MEDLDQSPLVSSSDSPPRPQPAFK 24 1 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4 Q9NQC3-5 RTN4 Reticulon-4 1 0 MEDLDQS(0.003)PLVS(0.247)S(0.694)S(0.04)DS(0.016)PPRPQPAFK 82.381 2.41E-06 113670000 4498.6 3809.3 4202.4 4963.4 4130 6931.1 7817.5 5906.1 6008 5262.3 TRUE FALSE FALSE 4142.531063 4138.558918 4358.144641 4942.862766 4080.752447 5493.51173 8036.83801 7706.842702 5348.937431 5445.164533 0.760772432 0.760042951 0.800369688 0.907752692 0.74942684 1.008878923 1.475958708 1.41535534 0.982327972 1 12.41075993 -4.853063189 3.848476133 0.862235681 1.450900669 0.875190771 0.088212742 0.061909456 1.721652793 0.015107148 0.052033456 1.40E-05 4.853063189 0.588664988 (ac)MEDMNEYSNIEEFAEGSK ddPTM_HeLa_Curcumin_4h_R1 4 MEDMNEYSNIEEFAEGSK 18 0 O14979-3;O14979-2;A0A087WU03 O14979-3 HNRNPDL Heterogeneous nuclear ribonucleoprotein D-like 0 0 ;;; ;;; 224.24 1.37E-113 29272000 16730.35 13007.42 13068.55 14590.52 14741.77 18450.82 15459.31 13151.88 15217.19 14388.11 FALSE FALSE TRUE 15406.12514 14131.72342 13552.88196 14530.14829 14565.98402 14623.91195 15893.05663 17161.82767 13547.90233 14888.09575 1.034794872 0.949196167 0.910316684 0.975957472 0.978364477 0.982255366 1.067500968 1.152721473 0.909982214 1 13.86187162 -4.455749765 2.636610305 0.996974413 1.157230735 0.590427823 0.044811208 0.190848489 2.179004127 0.006123807 0.054602798 3.50E-05 4.455749765 0.160256322 (ac)MEDS(ph)QDLNEQSVKK ddPTM_HeLa_Curcumin_4h_R1 3 MEDSQDLNEQSVKK 14 1 E9PLN6;F2Z2Y1;O95677-3;O95677-2;O95677-4;O95677;E7ESD5;O95677-5 E9PLN6 EYA4 Eyes absent homolog;Eyes absent homolog 4 1 0 MEDS(1)QDLNEQSVKK;MEDS(1)QDLNEQSVKK;MEDS(1)QDLNEQSVKK ;; 77.288 0.01129 34815000 5024.4 4693.3 5126.1 4796.6 4799.5 6792.2 5477.9 5292.9 5858 4876.3 TRUE FALSE FALSE 4626.713438 5098.967939 5316.077775 4776.75294 4742.269097 5383.421156 5631.595131 6906.680844 5215.392056 5045.751062 0.916952379 1.010546869 1.053575119 0.94668819 0.939853956 1.066921671 1.116106415 1.368811255 1.033620563 1 12.30085332 -3.877591595 1.004603644 0.967993474 1.8989278 0.857416017 0.04638858 0.906147265 0.421232695 0.007302116 1.090336044 0.000132559 3.877591595 0.930934327 (ac)MEEGGRDKAPVQPQQS(ph)PAAAPGGTDEKPSGK ddPTM_HeLa_Curcumin_4h_R1 3 MEEGGRDKAPVQPQQSPAAAPGGTDEKPSGK 31 3 Q13200;C9JPC0;F8WBS8 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 0 MEEGGRDKAPVQPQQS(1)PAAAPGGTDEKPSGK;MEEGGRDKAPVQPQQS(0.997)PAAAPGGT(0.003)DEKPS(0.001)GK;MEEGGRDKAPVQPQQS(0.999)PAAAPGGT(0.001)DEKPSGK ;; 57.347 0.00032981 170438600 10937.4 7703.2 7744.1 8591.3 6787.3 10801.6 8001.4 8175 12126.6 10955.7 TRUE FALSE FALSE 10071.69325 8369.030283 8031.103158 8555.751477 6706.36588 8561.226401 8225.897749 10667.51987 10796.34232 11336.40976 0.88843765 0.738243453 0.708434445 0.754714381 0.591577583 0.755197332 0.725617539 0.94099632 0.952359922 1 13.46867619 -7.562697995 1.283675902 0.966825332 0.73484532 0.552464099 0.083511442 0.197744873 0.658466867 0.01795585 0.018655297 2.74E-08 7.562697995 -0.231980012 (ac)MEEQPQMQDADEPADS(ph)GGEGR ddPTM_HeLa_Curcumin_4h_R1 1 MEEQPQMQDADEPADSGGEGR 21 0 D6RBJ6;B3KVZ3;Q9H3R5 D6RBJ6 CENPH Centromere protein H 1 0 MEEQPQMQDADEPADS(1)GGEGR 72.568 0.00090413 1572200 72.089 0 0 179.87 0 154.2 0 0 0 68.435 TRUE FALSE FALSE 66.38307958 0 0 179.1257456 0 122.2171818 0 0 0 70.81311116 0.937440518 0 0 2.529556217 0 1.725911767 0 0 0 1 6.145944597 -4.709476463 23.67455921 0.913747955 2.55E-07 0.10818213 0.813522504 70.66631395 32193.92726 0.095313116 0.356628085 1.95E-05 4.709476463 -0.9137477 (ac)MEGAAAPVAGDRPDLGLGAPGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 MEGAAAPVAGDRPDLGLGAPGSPR 24 1 O60285;O60285-2 O60285 NUAK1 NUAK family SNF1-like kinase 1 1 0 MEGAAAPVAGDRPDLGLGAPGS(1)PR;MEGAAAPVAGDRPDLGLGAPGS(1)PR;MEGAAAPVAGDRPDLGLGAPGS(1)PR;MEGAAAPVAGDRPDLGLGAPGS(1)PR ;;; 82.56 2.23E-07 84465000 516.75 443.445 316.63 521.68 497.289 235.174 366.83 232.61 410.84 365.777 TRUE FALSE FALSE 475.8486922 481.7744098 328.3645863 519.5214264 491.3591535 186.3962614 377.1222625 303.5317182 365.7718799 378.4877235 1.257236794 1.272893095 0.867569979 1.372624247 1.298216885 0.492476373 0.996392324 0.801959216 0.966403551 1 8.564102696 -5.275974505 24.99541368 1.145716581 0.786887582 0.458029686 0.191024481 536.6421166 922839.2395 0.026757894 0.060078488 5.30E-06 5.275974505 -0.358829 (ac)MEGIS(ph)NFKTPSK ddPTM_HeLa_Curcumin_4h_R1 1 MEGISNFKTPSK 12 1 Q96KB5;Q96KB5-2;E5RIE1 Q96KB5 PBK Lymphokine-activated killer T-cell-originated protein kinase 1 0 MEGIS(0.496)NFKT(0.494)PS(0.011)K 66.023 0.0035356 36736000 3875.6 3291.4 3174.4 3515.3 3915 6569.4 6143.7 1729 3442.7 3026.8 TRUE FALSE FALSE 3568.84217 3575.89395 3292.046056 3500.75462 3868.316182 5206.832388 6316.075687 2256.164141 3065.044423 3131.981075 1.139483951 1.141735491 1.051106625 1.1177445 1.23510203 1.662472494 2.016639161 0.720363274 0.978628015 1 11.61285978 -5.484916922 3.750073786 1.077242453 1.518830149 0.244384532 0.305686167 0.203221043 5.967666641 0.040316445 0.091446026 3.27E-06 5.484916922 0.441587696 (ac)MEGISNFKT(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 MEGISNFKTPSK 12 1 Q96KB5;Q96KB5-2;E5RIE1 Q96KB5 PBK Lymphokine-activated killer T-cell-originated protein kinase 1 0 MEGIS(0.082)NFKT(0.887)PS(0.032)K 67.519 0.0089808 35310000 4237.4 3688.8 4162.9 4465.7 4741.7 7352.8 7377.8 2125.6 4162.9 3585.7 TRUE FALSE FALSE 3902.005319 4007.643435 4317.180736 4447.222117 4685.158324 5827.746397 7584.801212 2773.685655 3706.240285 3710.302808 1.051667619 1.080139181 1.163565606 1.198614331 1.262742845 1.570692932 2.044253961 0.74756315 0.99890507 1 11.85732122 -5.840389958 1.374400922 1.034551271 1.497520013 0.233929977 0.300092972 0.36168703 1.367891898 0.043725175 0.106197513 1.44E-06 5.840389958 0.462968742 (ac)MEGQS(ph)VEELLAK ddPTM_HeLa_Curcumin_4h_R1 1 MEGQSVEELLAK 12 0 Q15050 Q15050 RRS1 Ribosome biogenesis regulatory protein homolog 1 0 MEGQS(1)VEELLAK 70.412 0.0013487 0 1408.3 1092.3 1188.1 1155.7 1311.8 1566.7 1398.9 1053.6 1480.6 1211.8 TRUE FALSE FALSE 1296.831569 1186.713545 1232.132031 1150.91802 1296.157642 1241.74876 1438.149369 1374.83779 1318.181884 1253.90996 1.034230216 0.946410494 0.982631984 0.917863369 1.033692756 0.990301377 1.146931929 1.096440601 1.051257209 1 10.29221804 -4.76540085 24.99945575 1.001954324 1.121686282 0.607530272 0.040526412 46.31637454 292296.3372 0.005579894 0.01769509 1.72E-05 4.76540085 0.119731958 (ac)MEGS(ph)LEREAPAGALAAVLK ddPTM_HeLa_Curcumin_4h_R1 1 MEGSLEREAPAGALAAVLK 19 1 M0R253;M0QX43;A0A3B3IU31;B4E3M2;Q5J8M5;P49366-2;P49366 M0R253 DHPS Deoxyhypusine synthase 1 0 MEGS(1)LEREAPAGALAAVLK 48.659 0.019646 2971800 1226.1 953.05 978.62 1200.5 934.01 1395.2 1200.5 1497.8 1512.5 1332.7 TRUE FALSE FALSE 1129.052891 1035.427395 1014.888518 1195.532649 922.8725408 1105.819793 1234.182799 1954.472325 1346.582534 1379.011226 0.818740899 0.750847691 0.735953775 0.866949178 0.669227722 0.801893249 0.894976615 1.417299793 0.976484099 1 10.42941849 -4.263049591 4.838888456 0.860915107 1.44687829 0.745490245 0.10124423 0.082429402 5.594347985 0.016823457 0.161662385 5.46E-05 4.263049591 0.585963183 (ac)MEITIRNS(ph)PYR ddPTM_HeLa_Curcumin_4h_R1 2 MEITIRNSPYR 11 1 A0A0D9SEI3;A0A0D9SER5;A0A0D9SEN2;P21127-6;P21127-9;P21127-8;P21127-3;P21127-2;P21127;Q9UQ88-9;A0A087WYI9;A0A087X1I0 A0A0D9SEI3 CDK11B;CDK11A Cyclin-dependent kinase 11B;Cyclin-dependent kinase 11A 1 0 MEIT(0.001)IRNS(0.999)PYR;MEITIRNS(1)PYR ; 111.5 2.05E-05 23521000 739.18 630.97 562.63 740.58 621.49 865.29 499.98 545.8 648.79 781.29 TRUE FALSE FALSE 680.673123 685.5082353 583.4815627 737.5156762 614.0791377 685.8191002 514.0080932 712.2119074 577.6193602 808.4397693 0.841958979 0.847939774 0.721737827 0.912270405 0.759585514 0.848324298 0.635802583 0.880970895 0.714486573 1 9.658996483 -9.255775727 0.296563614 1.096277093 0.76939962 0 0.117971104 2.237535489 0.266856831 0.257051032 0.043570327 5.55E-10 9.255775727 -0.326877473 (ac)MET(ph)MASPGKDNYR ddPTM_HeLa_Curcumin_4h_R1 15 METMASPGKDNYR 13 1 S4R3E5;O60684 S4R3E5 KPNA6 Importin subunit alpha-7 1 0 MET(0.999)MAS(0.001)PGKDNYR;MET(0.95)MAS(0.05)PGKDNYR;MET(0.994)MAS(0.006)PGKDNYR;MET(0.952)MAS(0.048)PGKDNYR;MET(0.986)MAS(0.014)PGKDNYR;MET(0.992)MAS(0.008)PGKDNYR;MET(0.979)MAS(0.021)PGKDNYR;MET(0.921)MAS(0.079)PGKDNYR;MET(0.901)MAS(0.099)PGKDNYR;MET(0.968)MAS(0.032)PGKDNYR;MET(0.997)MAS(0.003)PGKDNYR;MET(0.982)MAS(0.018)PGKDNYR;MET(0.936)MAS(0.064)PGKDNYR;MET(0.888)MAS(0.112)PGKDNYR;MET(0.89)MAS(0.11)PGKDNYR ;;;;;;;;;;;;;; 141.37 4.58E-13 2575872000 52994.6 44048.2 47437.1 47146.7 45993.5 59353.5 51845.2 30256.3 52326 46069.5 TRUE FALSE FALSE 48800.02149 47855.53013 49195.16066 46951.61945 45445.05755 47042.91505 53299.83678 39481.30659 46585.96871 47670.4117 1.023696246 1.003883298 1.031985227 0.984921627 0.953317916 0.986836769 1.118090549 0.828214089 0.977251235 1 15.54080646 -6.134578223 7.560435172 1.012201467 0.981484693 0.050091463 0.067037429 0.690749151 39.58890713 0.009011158 0.0149904 7.34E-07 6.134578223 -0.030716774 (ac)MET(ph)PSQRR ddPTM_HeLa_Curcumin_4h_R1 4 METPSQRR 8 1 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 MET(0.916)PS(0.084)QRR;MET(0.928)PS(0.072)QRR;MET(0.86)PS(0.14)QRR;MET(0.931)PS(0.069)QRR ;;; 57.59 0.0057407 41453800 0 110.85 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 120.4313801 0 0 0 0 0 0 0 0 0 (ac)METMAS(ph)PGKDNYR ddPTM_HeLa_Curcumin_4h_R1 5 METMASPGKDNYR 13 1 S4R3E5;O60684 S4R3E5 KPNA6 Importin subunit alpha-7 1 0 MET(0.27)MAS(0.73)PGKDNYR;MET(0.084)MAS(0.916)PGKDNYR;MET(0.371)MAS(0.629)PGKDNYR;MET(0.32)MAS(0.68)PGKDNYR;MET(0.064)MAS(0.936)PGKDNYR ;;;; 113.52 0.00059507 436166600 16721.74 13908.9 15680.63 15504.93 14898.5 18729.8 16790.9 11306.15 17831.9 14905.31 TRUE FALSE FALSE 15398.19663 15111.12334 16261.76794 15440.77471 14720.84512 14845.02835 17262.00746 14753.34309 15875.78518 15423.26841 0.998374419 0.979761419 1.054365878 1.001135057 0.95445691 0.962508591 1.119218508 0.956563985 1.029339875 1 13.91282091 (ac)METPSQR ddPTM_HeLa_Curcumin_4h_R1 1 METPSQR 7 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 46.37 0.014465 332140 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 (ac)MEVAEPS(ph)SPTEEEEEEEEHSAEPR ddPTM_HeLa_Curcumin_4h_R1 1 MEVAEPSSPTEEEEEEEEHSAEPR 24 0 M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8;M0R3H9 M0QXG9 BABAM1 BRISC and BRCA1-A complex member 1 1 0 MEVAEPS(0.646)S(0.214)PT(0.14)EEEEEEEEHSAEPR 47.05 0.0031004 3948100 563.64 390.51 343.37 465.4 335.09 384.5 248.54 364.89 502.9 406.58 TRUE FALSE FALSE 519.0272992 424.2639443 356.0955943 463.4742981 331.0942706 304.7503658 255.5133635 476.1432813 447.7331282 420.7086247 1.233697787 1.008450788 0.846418574 1.101651525 0.786991878 0.724373944 0.607340445 1.131764963 1.064235677 1 8.716677584 -6.271512724 1.071929186 1.105190999 0.800509035 0.288667471 0.160271074 0.391965877 0.891061428 0.02948276 0.060513529 5.35E-07 6.271512724 -0.304681964 (ac)MEVAEPS(ph)SPTEEEEEEEEHSAEPRPR ddPTM_HeLa_Curcumin_4h_R1 5 MEVAEPSSPTEEEEEEEEHSAEPRPR 26 1 M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8;M0R3H9 M0QXG9 BABAM1 BRISC and BRCA1-A complex member 1 1 0 MEVAEPS(0.333)S(0.333)PT(0.333)EEEEEEEEHSAEPRPR;MEVAEPS(0.447)S(0.447)PT(0.106)EEEEEEEEHSAEPRPR;MEVAEPS(0.37)S(0.37)PT(0.259)EEEEEEEEHSAEPRPR;MEVAEPS(0.333)S(0.333)PT(0.333)EEEEEEEEHSAEPRPR;MEVAEPS(0.445)S(0.445)PT(0.109)EEEEEEEEHSAEPRPR ;;;; 69.272 1.70E-05 249292000 422.992 337.394 410.722 500.843 268.499 489.73 204.58 0 553.89 595.64 TRUE FALSE FALSE 389.5117369 366.556834 425.9437186 498.7706444 265.2973248 388.1544776 210.3199642 0 493.1296528 616.3384457 0.631977024 0.594733034 0.691087375 0.809247984 0.43044098 0.629774891 0.341241027 0 0.800095558 1 9.267578975 -5.826131059 0.194491911 1.049071307 4.85E-28 0.635000429 0.160896599 3.583978597 0.260390399 0.329467588 1.055236364 1.49E-06 5.826131059 -1.049071307 (ac)MEVAEPSSPT(ph)EEEEEEEEHSAEPRPR ddPTM_HeLa_Curcumin_4h_R1 1 MEVAEPSSPTEEEEEEEEHSAEPRPR 26 1 M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8;M0R3H9 M0QXG9 BABAM1 BRISC and BRCA1-A complex member 1 1 0 MEVAEPS(0.182)S(0.182)PT(0.637)EEEEEEEEHSAEPRPR 77.51 1.78E-05 57992000 60.549 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 55.75648276 0 0 0 0 0 0 0 0 0 0 (ac)MEVKPPPGRPQPDS(ph)GR ddPTM_HeLa_Curcumin_4h_R1 4 MEVKPPPGRPQPDSGR 16 2 P51991 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 0 MEVKPPPGRPQPDS(1)GR;MEVKPPPGRPQPDS(1)GR;MEVKPPPGRPQPDS(1)GR;MEVKPPPGRPQPDS(1)GR ;;; 63.462 0.0054213 113769000 9746.3 8558.55 8984.93 9215.98 10983.5 14555.1 12738.2 6672.78 8707.52 7698.31 TRUE FALSE FALSE 8974.870071 9298.312926 9317.91941 9177.846717 10852.52894 11536.20819 13095.59961 8707.279904 7752.326841 7965.825699 1.126671661 1.167275469 1.169736793 1.152152591 1.36238594 1.44821248 1.643972653 1.093079391 0.973198151 1 12.9596082 -6.201475461 0.654951282 1.047067464 1.434748581 0.509432317 0.139334261 0.43973416 0.361545982 0.028922459 0.079607932 6.29E-07 6.201475461 0.387681117 (ac)MEVS(ph)PLQPVNENMQVNK ddPTM_HeLa_Curcumin_4h_R1 1 MEVSPLQPVNENMQVNK 17 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 MEVS(1)PLQPVNENMQVNK 50.484 0.0061051 16742000 1218.2 596.4 927.92 1222.6 933.94 1317.6 1182.1 378.04 1159.2 761.75 TRUE FALSE FALSE 1121.778185 647.9501585 962.3095315 1217.541205 922.8033755 1044.314908 1215.266545 493.3026557 1032.03866 788.2207558 1.423177677 0.822041482 1.220862968 1.544670318 1.170742294 1.324901558 1.541784501 0.625843271 1.309326927 1 9.622455929 -9.642407274 1.464439741 0.999708339 1.251944241 0 0.296190393 0.776304348 2.987107194 0.190251566 0.042901566 2.28E-10 9.642407274 0.252235902 (ac)MGLLS(ph)QGSPLS(ph)WEETKR ddPTM_HeLa_Curcumin_4h_R1 1 MGLLSQGSPLSWEETKR 17 1 A0A0C4DGB2;E1CEI4;P48506;D6RGF8 A0A0C4DGB2 GCLC Glutamate--cysteine ligase catalytic subunit 2 0 MGLLS(0.997)QGS(0.004)PLS(0.969)WEET(0.03)KR 68.329 0.0012513 0 2169.1 1931.6 2244.6 1717.5 1881.5 2670.3 2545.3 2531.9 2727.6 2142.4 TRUE FALSE FALSE 1997.413446 2098.558897 2327.786851 1710.39344 1859.064341 2116.44968 2616.714268 3303.864655 2428.389104 2216.848241 0.901014968 0.946640757 1.050043394 0.771542864 0.83860695 0.954711126 1.180375914 1.490343179 1.095424152 1 11.1142943 -4.431683689 2.153317338 0.936977491 1.541585352 0.781355297 0.090221307 0.140405179 0.937692533 0.011633517 0.141155075 3.70E-05 4.431683689 0.604607861 (ac)MHRDS(ph)CPLDCK ddPTM_HeLa_Curcumin_4h_R1 5 MHRDSCPLDCK 11 1 P84103;P84103-2;A0A087X2D0 P84103 SRSF3 Serine/arginine-rich splicing factor 3 1 0 MHRDS(1)CPLDCK;MHRDS(1)CPLDCK;MHRDS(1)CPLDCK;MHRDS(1)CPLDCK;MHRDS(1)CPLDCK ;;;; 81.625 0.0061995 60137000 13382.47 11942.22 12116.22 13890.48 12958.96 18367.08 14659.44 14717.41 14733.53 12153.77 TRUE FALSE FALSE 12323.23338 12974.45228 12565.25777 13833.00487 12804.43287 14557.54057 15070.74443 19204.68056 13117.29862 12576.1126 0.979892099 1.031674309 0.999136869 1.099942829 1.018155075 1.157554884 1.198362714 1.527076066 1.043032854 1 13.61839842 -1 0.592165839 0.994793669 32.45306099 0.941667924 0.037749303 18.56571944 0.135844747 0.005590559 756.3191934 0.1 1 31.45826732 (ac)MHS(ph)EAEESKEVATDVFNSK ddPTM_HeLa_Curcumin_4h_R1 1 MHSEAEESKEVATDVFNSK 19 1 O95379 O95379 TNFAIP8 Tumor necrosis factor alpha-induced protein 8 1 0 MHS(0.965)EAEES(0.035)KEVATDVFNSK 61.477 0.0033676 3452700 980.7 975.75 917.3 1021.2 955.51 1413.4 1210.2 1239.4 1111.3 1199.2 TRUE FALSE FALSE 903.0765602 1060.089482 951.2959449 1016.974545 944.1161673 1120.244908 1244.154955 1617.287355 989.3931703 1240.872111 0.727775693 0.854310024 0.766634963 0.81956435 0.760848889 0.902788368 1.002645594 1.303347332 0.797336939 1 10.27713872 -4.277399542 1.736495164 0.8490224 1.449092142 0.787840129 0.075506221 0.449035237 1.348881503 0.015550743 0.439615014 5.28E-05 4.277399542 0.600069741 (ac)MIPLEKPGS(ph)GGSSPGATSGSGR ddPTM_HeLa_Curcumin_4h_R1 1 MIPLEKPGSGGSSPGATSGSGR 22 1 Q9UEE5 Q9UEE5 STK17A Serine/threonine-protein kinase 17A 1 0 MIPLEKPGS(0.323)GGS(0.323)S(0.323)PGAT(0.024)S(0.006)GS(0.002)GR 52.19 0.0012645 4622500 1150.7 1100.2 828.41 1101 981.37 1148.9 853.34 956.89 1116 958.93 TRUE FALSE FALSE 1059.620881 1195.296386 859.1116033 1096.444354 969.6678037 910.6051892 877.2824238 1248.641356 993.5775921 992.2527461 1.067894128 1.204628952 0.865819325 1.105005109 0.97723872 0.91771496 0.884132019 1.258390426 1.00133519 1 9.95456384 -6.738778085 24.99986009 1.045899613 0.995863384 0.05534366 0.121017914 693.1499717 764678.9921 0.017986904 0.025426853 1.82E-07 6.738778085 -0.050036229 (ac)MLS(ph)PEAER ddPTM_HeLa_Curcumin_4h_R1 1 MLSPEAER 8 0 Q9NUG6 Q9NUG6 PDRG1 p53 and DNA damage-regulated protein 1 1 0 MLS(1)PEAER 61.65 0.0075138 2812300 62.336 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 57.40203982 0 0 0 0 0 0 0 0 0 0 (ac)MLTDSGGGGTS(ph)FEEDLDSVAPR ddPTM_HeLa_Curcumin_4h_R1 2 MLTDSGGGGTSFEEDLDSVAPR 22 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;E9PDP5;D6RHC4;Q8IWZ3-5;Q8IWZ3-3;Q8IWZ3-2 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 0 MLT(0.001)DS(0.017)GGGGT(0.02)S(0.962)FEEDLDSVAPR;MLTDS(0.001)GGGGT(0.199)S(0.8)FEEDLDSVAPR ; 121.01 1.37E-17 5599400 0 133.4 0 62.576 0 0 0 205.432 0 117.75 TRUE FALSE FALSE 0 144.9305016 0 62.31707709 0 0 0 268.0672711 0 121.8418037 0 1.189497341 0 0.511458918 0 0 0 2.200125596 0 1 6.928865394 -9.61043661 1.410150874 1.000455935 0.383328155 0 0.751277459 0.78942136 2.814426396 0.458505938 0.105136921 2.45E-10 9.61043661 -0.617127781 (ac)MMEGLDDGPDFLSEEDR ddPTM_HeLa_Curcumin_4h_R1 5 MMEGLDDGPDFLSEEDR 17 0 G3V5X9;Q9UNH7;G3V2U1;H0YJF8;G3V4Z5 G3V5X9 SNX6 "Sorting nexin-6;Sorting nexin-6, N-terminally processed" 0 0 ;;;; ;;;; 200.93 7.36E-31 14028200 126.85 185.737 0 0 247.61 60.113 120.27 0 0 64.173 FALSE FALSE TRUE 116.8096886 201.7912787 0 0 244.6574125 47.64488619 123.6444525 0 0 66.40300697 1.759102396 3.038887663 0 0 3.684432733 0.717510974 1.862030925 0 0 1 6.053176668 (ac)MMGTSQGHVAR ddPTM_HeLa_Curcumin_4h_R1 1 MMGTSQGHVAR 11 0 Q9UL54-3 Q9UL54-3 TAOK2 Serine/threonine-protein kinase TAO2 0 0 41.704 0.01622 1476100 391.43 186.57 304.9 358.18 169.98 344.25 331.79 158.91 477.06 275.82 FALSE FALSE TRUE 360.4479025 202.6962795 316.1998622 356.6979461 167.9530995 272.8486695 341.0991344 207.3609275 424.7277115 285.4047245 1.262936005 0.710206461 1.107899888 1.249796922 0.588473438 0.956006142 1.195141864 0.726550438 1.488159358 1 8.156865407 -6.437842103 0.923364232 1.10806957 0.924307971 0.144927118 0.251795464 0.990329731 1.682010783 0.043347596 0.084493436 3.65E-07 6.437842103 -0.183761599 (ac)MNGK(ac)RPAEPGPAR ddPTM_HeLa_Curcumin_4h_R1 1 MNGKRPAEPGPAR 13 2 H3BR02;H3BR79;A0A0A0MTR2;Q8N543 H3BR02 OGFOD1 Prolyl 3-hydroxylase OGFOD1 0 1 MNGK(1)RPAEPGPAR 45.908 0.0013759 3601400 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)MNLLPNIES(ph)PVTR ddPTM_HeLa_Curcumin_4h_R1 2 MNLLPNIESPVTR 13 0 E9PM69;P17980 E9PM69 PSMC3 26S protease regulatory subunit 6A 1 0 MNLLPNIES(0.989)PVT(0.011)R;MNLLPNIES(0.989)PVT(0.011)R ; 183.28 5.32E-22 9736200 48.988 132.01 274.71 112.76 102.6 272.6 62.967 0 0 169.07 TRUE FALSE FALSE 45.11054811 143.4203562 284.8909943 112.293429 101.376562 216.0596872 64.73368455 0 0 174.9451699 0.257855351 0.819801748 1.628458759 0.641877847 0.579476199 1.235013732 0.370022702 0 0 1 7.450759023 -4.528531588 24.58851137 0.75224024 0.092505459 0.23900358 0.439049533 106.6216587 463783.2039 0.058928341 0.221943234 2.96E-05 4.528531588 -0.659734781 (ac)MNPVY(ph)SPGSSGVPYANAK ddPTM_HeLa_Curcumin_4h_R1 1 MNPVYSPGSSGVPYANAK 18 0 A1KXE4-2;A1KXE4 A1KXE4-2 FAM168B Myelin-associated neurite-outgrowth inhibitor 1 0 MNPVY(0.83)S(0.145)PGS(0.012)S(0.004)GVPY(0.008)ANAK 44.511 0.0088347 3015200 2376 1903.1 1707.5 2247.3 2030.2 2940.7 2033.2 1937.7 2010.7 1709.9 TRUE FALSE FALSE 2187.937093 2067.595484 1770.781452 2238.001268 2005.991191 2330.765671 2090.24612 2528.49581 1790.131241 1769.318898 1.236598499 1.168582717 1.00082662 1.264894232 1.133764633 1.317323674 1.181384612 1.429078621 1.011762912 1 10.78897838 -13.51531504 0.040264129 5.02E-07 1.822090722 0.512826223 0.095210487 464.7611669 1.495432896 59.02319394 19.06524416 3.05E-14 13.51531504 1.82209022 (ac)MNS(ph)MDR ddPTM_HeLa_Curcumin_4h_R1 1 MNSMDR 6 0 A0A087WYE6;Q9ULJ6 A0A087WYE6 ZMIZ1 Zinc finger MIZ domain-containing protein 1 1 0 MNS(1)MDR 42.773 0.0094445 0 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)MNT(ph)SPGTVGSDPVILATAGYDHTVR ddPTM_HeLa_Curcumin_4h_R1 1 MNTSPGTVGSDPVILATAGYDHTVR 25 0 H3BQ74;I3L2E7;H3BR38;H3BM50;H3BPU5;H3BR25;H3BPT1;H3BN58;H3BSZ4;A0A0A0MR05;Q9BVC4-5;Q9BVC4 H3BQ74 MLST8 Target of rapamycin complex subunit LST8 1 0 MNT(0.317)S(0.317)PGT(0.317)VGS(0.049)DPVILATAGYDHTVR 48.867 0.019417 4242500 968.6 1130.1 1021.9 1161.2 1074.6 1007.6 994.16 824.46 1155.2 975.42 TRUE FALSE FALSE 891.9342879 1227.780808 1059.772513 1156.395262 1061.786097 798.612402 1022.053454 1075.834059 1028.47745 1009.315772 0.883701922 1.21644865 1.049991035 1.145721977 1.051986034 0.791241377 1.012620115 1.065904336 1.01898482 1 9.979161888 (ac)MNTAPS(ph)RPSPTR ddPTM_HeLa_Curcumin_4h_R1 1 MNTAPSRPSPTR 12 1 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 0 MNT(0.001)APS(0.86)RPS(0.103)PT(0.037)R 53.034 0.00054261 0 469.44 256.3 397.1 369.81 362.25 513.36 327.67 318.77 492.7 265.25 TRUE FALSE FALSE 432.2833286 278.4534299 411.8168753 368.2798242 357.9304053 406.8833492 336.8635383 415.9615056 438.6520427 274.4674178 1.574989601 1.014522715 1.500421721 1.341797971 1.304090694 1.482446815 1.227335256 1.515522349 1.598193499 1 8.100491086 -9.53818567 1.268214746 0.997655541 1.384715444 0 0.241505459 0.328699506 0.937497213 0.110903984 0.02573537 2.90E-10 9.53818567 0.387059903 (ac)MNTAPSRPS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 2 MNTAPSRPSPTR 12 1 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 0 MNTAPS(0.008)RPS(0.734)PT(0.258)R;MNTAPS(0.001)RPS(0.808)PT(0.191)R ; 71.558 0.011245 114562000 2026.24 2511.2 1946.2 2190.36 1870.77 2119.41 1857.91 1716.96 2445.02 2207.02 TRUE FALSE FALSE 1865.860966 2728.256938 2018.327884 2181.296871 1848.46229 1679.820475 1910.037954 2240.4532 2176.807423 2283.713781 0.817029254 1.194658 0.883791962 0.955153351 0.809410665 0.73556524 0.836373617 0.981056917 0.953187497 1 11.15716613 -5.762578511 24.99894944 0.935120554 0.832797004 0.209687478 0.109941655 46.34409303 1017083.938 0.017457906 0.032983345 1.73E-06 5.762578511 -0.10232355 (ac)MNTAPSRPS(ph)PTRR ddPTM_HeLa_Curcumin_4h_R1 1 MNTAPSRPSPTRR 13 2 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 0 MNT(0.001)APS(0.011)RPS(0.494)PT(0.494)RR 41.48 0.019229 49093000 138.54 0 129.17 72.328 190.16 152.43 132.44 212.16 169.72 0 TRUE FALSE FALSE 127.5744128 0 133.9571538 72.0287259 187.8924662 120.8142998 136.15591 276.8466073 151.1021406 0 0 (ac)MNVDHEVNLLVEEIHR ddPTM_HeLa_Curcumin_4h_R1 2 MNVDHEVNLLVEEIHR 16 0 Q5SZC9;Q9P1F3 Q5SZC9 ABRACL Costars family protein ABRACL 0 0 ; ; 82.837 4.06E-11 5823200 388.89 373.48 240.774 390.8 281.05 278.476 226.23 328.79 201.91 185.19 FALSE FALSE TRUE 358.1089461 405.761947 249.6972962 389.1829731 277.6986623 220.7169385 232.5774049 429.0365574 179.7609782 191.6253387 1.868797459 2.117475433 1.303049471 2.030957783 1.449175063 1.151814995 1.213709035 2.238934372 0.938085638 1 7.582144532 -9.387575778 1.133900176 1.003075498 1.662895673 0.362357061 0.369899985 0.480971579 1.114152419 0.246556936 0.064414881 4.10E-10 9.387575778 0.659820174 (ac)MNVT(ph)PEVK ddPTM_HeLa_Curcumin_4h_R1 1 MNVTPEVK 8 0 F8W895;A0A0A0MRK1;Q5T3I0;E9PPY4;F2Z3C6 F8W895 GPATCH4 G patch domain-containing protein 4 1 0 MNVT(1)PEVK 71.451 0.018561 2634000 4442 3971.7 4486.4 5150.8 4270.3 7303.5 6016.3 2660.2 4812 3806.9 TRUE FALSE FALSE 4090.411013 4314.99605 4652.669931 5129.487354 4219.379462 5788.671773 6185.101186 3471.282734 4284.135639 3939.189492 1.038388994 1.095402001 1.181123665 1.302168216 1.071128838 1.46950833 1.570145635 0.881217505 1.087567797 1 11.9436831 -6.666262892 0.958806466 1.011524037 1.295207617 0.209167161 0.182068526 0.446803673 0.820869529 0.033228487 0.055296582 2.16E-07 6.666262892 0.28368358 (ac)MPHPRRYHS(ph)S(ph)ER ddPTM_HeLa_Curcumin_4h_R1 1 MPHPRRYHSSER 12 2 B1AVT0;P49760-2;P49760-3;P49760 B1AVT0 CLK2 Dual specificity protein kinase CLK2 2 0 MPHPRRY(0.141)HS(0.866)S(0.993)ER 46.819 0.020167 3838700 68.276 0 114.76 213.6 232.88 218.22 174.81 113.65 189.56 142.83 TRUE FALSE FALSE 62.87188256 0 119.0131066 212.7161798 230.1030581 172.9587122 179.7146981 148.3013618 168.7657423 147.7933319 0.425404054 0 0.805267092 1.439281307 1.556924492 1.170274125 1.215986512 1.003437435 1.141903631 1 7.207437369 -6.379836447 5.328330117 0.655755631 1.280914093 0.470607884 0.322215693 0.168623397 6.756862487 0.053880782 0.082802921 4.17E-07 6.379836447 0.625158462 (ac)MQNDAGEFVDLYVPR ddPTM_HeLa_Curcumin_4h_R1 1 MQNDAGEFVDLYVPR 15 0 Q8WVC2;P63220;Q9BYK2;Q9BYK1 Q8WVC2 RPS21 40S ribosomal protein S21 0 0 108.37 0.017464 1964400 237.64 371.24 316.51 304.85 402.21 291.85 180.71 0 339.79 283.82 FALSE FALSE TRUE 218.8305432 403.3283314 328.240139 303.5886115 397.4139084 231.3170202 185.7802362 0 302.5158871 293.6827239 0.745125693 1.373347148 1.117669214 1.033729896 1.35320833 0.787642586 0.632588236 0 1.030077231 1 8.19811459 -4.452230593 2.119184918 0.971602063 9.29E-20 0.708271646 0.204905146 0.242003185 1.592322686 0.033001952 0.381599617 3.53E-05 4.452230593 -0.971602063 down (ac)MS(ph)LPSS(ph)CEYLTLGK ddPTM_HeLa_Curcumin_4h_R1 1 MSLPSSCEYLTLGK 14 0 A0A1B0GW84 A0A1B0GW84 2 0 MS(0.988)LPS(0.107)S(0.451)CEY(0.452)LT(0.002)LGK 51.762 0.0053557 8991300 5214.1 4165.4 4297.6 4880.2 5006.7 5649.2 3901 3757.1 4931.5 4741.5 TRUE FALSE FALSE 4801.398483 4525.438615 4456.872837 4860.007025 4946.998372 4477.49224 4010.451561 4902.622494 4390.526788 4906.266772 0.978625645 0.92237924 0.908404097 0.990571294 1.008301954 0.912606764 0.817414084 0.99925722 0.894881382 1 12.26040997 -6.443552217 0.216661455 1.01586631 0.886982244 0 0.063429694 4.613679037 0.572992494 0.094798632 0.20110341 3.60E-07 6.443552217 -0.128884066 (ac)MS(ph)PTPPLFSLPEAR ddPTM_HeLa_Curcumin_4h_R1 2 MSPTPPLFSLPEAR 14 0 A0A087WWS1;Q96FV9;J3KRD7;J3QQZ3;J3KT14;Q96FV9-2 A0A087WWS1 THOC1 THO complex subunit 1 1 0 MS(0.924)PT(0.076)PPLFSLPEAR;MS(0.989)PT(0.011)PPLFSLPEAR ; 112.94 0.00062348 2433400 581.71 461.49 616.76 525.89 569.79 874.08 649.79 443.16 594.14 730.99 TRUE FALSE FALSE 535.6670397 501.3791392 639.6176682 523.7140065 562.9956264 692.7859551 668.0213586 578.2774439 528.9643285 756.3918481 0.708187219 0.66285635 0.845616819 0.69238452 0.744317417 0.915908807 0.883168374 0.764520989 0.699325792 1 9.562990005 -9.377285951 1.109291174 0.99960903 0.77471382 0 0.12058326 0.333190773 0.735451215 0.057510164 0.014923487 4.19E-10 9.377285951 -0.22489521 (ac)MS(ph)TRSVSSSS(ph)YRR ddPTM_HeLa_Curcumin_4h_R1 1 MSTRSVSSSSYRR 13 2 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 2 0 MS(0.493)T(0.493)RS(0.013)VS(0.018)S(0.026)S(0.013)S(0.565)Y(0.379)RR 43.282 0.020065 11316000 440.91 515.08 553.66 541.21 510.8 606.18 588.41 369.82 606.51 385.29 TRUE FALSE FALSE 406.0115083 559.60122 574.1791266 538.9706164 504.7090436 480.4514349 604.919201 482.5764156 539.9773704 398.6787988 1.018392524 1.403639275 1.440204817 1.351891844 1.265954059 1.205109066 1.517309681 1.210439123 1.35441707 1 8.639083077 -7.268807668 24.39377979 1.008685345 1.344773581 0.224211838 0.143476898 139.0383434 460305.5864 0.015081119 0.017433799 5.39E-08 7.268807668 0.336088236 (ac)MSQYT(ph)EK ddPTM_HeLa_Curcumin_4h_R1 1 MSQYTEK 7 0 O43164-2;O43164 O43164-2 PJA2 E3 ubiquitin-protein ligase Praja-2 1 0 MS(0.001)QY(0.198)T(0.801)EK 57.859 0.018527 59916000 1199.5 1875.9 1598.2 1952.1 1429.5 1228.7 712.23 1209.3 2117.6 2206.8 TRUE FALSE FALSE 1104.558309 2038.044437 1657.430698 1944.022727 1412.454146 973.8537697 732.2132569 1578.010003 1885.304578 2283.486136 0.483715794 0.892514478 0.725833484 0.851339843 0.618551663 0.42647676 0.32065588 0.691053026 0.825625586 1 11.15702232 -13.52287875 0.300126321 4.433443289 0.57919646 0.270972313 0.178270285 37.58064296 0.508636134 78.07970225 0.07790318 3.00E-14 13.52287875 -3.854246829 (ac)MT(ph)PPQQPPPLR ddPTM_HeLa_Curcumin_4h_R1 2 MTPPQQPPPLR 11 0 A0A0A0MSF0;D6RA68;A0A0A0MSC7;Q9H9P5-2;Q9H9P5-1 A0A0A0MSF0 UNKL 1 0 MT(1)PPQQPPPLR;MT(1)PPQQPPPLR ; 113.69 0.005489 4798200 1150.53 1131.12 1010.96 1502.57 1212.47 1505.81 745.61 791.12 1256.45 1382.14 TRUE FALSE FALSE 1059.464336 1228.888973 1048.427067 1496.352763 1198.012087 1193.488032 766.5298099 1032.328846 1118.620578 1430.169262 0.740796467 0.859261211 0.73307901 1.046276691 0.837671539 0.834508239 0.535971392 0.721822845 0.782159572 1 10.48197019 -13.52287875 0.240826354 2.279333086 0.756909863 0 0.138957902 46.17858157 0.60390587 28.10864664 0.083574635 3.00E-14 13.52287875 -1.522423223 (ac)MT(ph)T(ph)ETGPDS(ph)EVK ddPTM_HeLa_Curcumin_4h_R1 1 MTTETGPDSEVK 12 0 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q4VXN8;Q4VXN7;Q4VXN6;Q4VXN5 A0A1B0GTW6 EPB41L1 Band 4.1-like protein 1 3 0 MT(0.763)T(0.954)ET(0.346)GPDS(0.936)EVK 54.871 0.0092134 0 1340.1 936.77 1113.5 923.38 1338.2 1537 865.03 766.11 1439.7 968.35 TRUE FALSE FALSE 1234.029671 1017.740225 1154.76729 919.5592982 1322.242839 1218.208874 889.3004137 999.6934123 1281.768512 1002.00009 1.231566427 1.015708715 1.152462261 0.917723768 1.319603513 1.21577721 0.887525283 0.997697926 1.279209976 1 9.968666923 -4.751989147 24.98859891 1.114955722 0.942611574 0.262403307 0.127304454 221.8547749 586622.2361 0.017458282 0.063593517 1.77E-05 4.751989147 -0.172344148 (ac)MT(ph)T(ph)SQKHR ddPTM_HeLa_Curcumin_4h_R1 2 MTTSQKHR 8 1 E9PJJ8;O75531 E9PJJ8 BANF1 "Barrier-to-autointegration factor;Barrier-to-autointegration factor, N-terminally processed" 2 0 MT(0.984)T(0.922)S(0.094)QKHR;MT(0.877)T(0.857)S(0.266)QKHR ; 46.158 0.015071 21030200 15128.4 15843.7 16503.4 14403.8 16728 15966.8 11906.1 11699.2 13844.6 13117.5 TRUE FALSE FALSE 13930.97118 17213.15883 17115.03052 14344.20089 16528.52953 12655.1057 12240.15312 15266.23222 12325.88202 13573.33215 1.026348654 1.268160142 1.260930649 1.056792889 1.217720847 0.932350698 0.901779533 1.124722511 0.908095513 1 13.72848731 -3.923470492 20.32231632 1.050805435 3.779740214 0.010484365 0.133820018 1758.794086 454955.5601 0.01816967 5656.780709 0.00011927 3.923470492 2.728934779 (ac)MVDYSVWDHIEVS(ph)DDEDETHPNIDTASLFR ddPTM_HeLa_Curcumin_4h_R1 1 MVDYSVWDHIEVSDDEDETHPNIDTASLFR 30 0 K7EQA9;Q16543;K7EJ06;K7EKQ2 K7EQA9 CDC37 "Hsp90 co-chaperone Cdc37;Hsp90 co-chaperone Cdc37, N-terminally processed" 1 0 MVDY(0.311)S(0.329)VWDHIEVS(0.347)DDEDET(0.012)HPNIDTASLFR 43.068 0.0025345 1700400 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)NGLAT(ph)S(ph)LGK ddPTM_HeLa_Curcumin_4h_R1 1 NGLATSLGK 9 0 O15034-2 O15034-2 2 0 NGLAT(1)S(1)LGK 89.029 0.014606 9135300 695.65 534.69 728.48 536.2 1968.7 2868.9 1220.2 634.47 1995.9 765.71 TRUE FALSE FALSE 640.5885685 580.9062211 755.4781096 533.9813465 1945.224538 2273.857801 1254.435528 827.9169823 1776.954763 792.3183655 0.808498952 0.733172733 0.953503216 0.67394796 2.455104694 2.869878952 1.583246814 1.044929688 2.242728228 1 9.629936433 -5.768384913 24.99916406 0.881698468 2.022329047 0.312402812 0.632129047 86.5584174 311552.1392 0.070008716 0.12892835 1.70E-06 5.768384913 1.140630579 (ac)PCSEET(ph)PAISPSKR ddPTM_HeLa_Curcumin_4h_R1 1 PCSEETPAISPSKR 14 1 P33316-2;H0YNJ9 P33316-2 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 1 0 PCS(0.098)EET(0.771)PAIS(0.092)PS(0.038)KR 63.16 0.001014 4763700 2096.4 2010 2266.5 1992.3 2963.8 3074.3 2567.2 2551 2620.8 2257.1 TRUE FALSE FALSE 1930.467728 2183.735444 2350.498484 1984.05639 2928.458621 2436.655525 2639.228723 3328.788157 2333.304797 2335.534057 0.826563724 0.935004753 1.006407283 0.849508653 1.253871084 1.043296936 1.130032215 1.425279219 0.999045503 1 11.18953677 -1.000013338 0.45018263 0.918580396 12.06891188 0.643141682 0.103312081 34.23100844 0.369265909 0.023089821 353.875224 0.099996929 1.000013338 11.15033148 (ac)S(ph)AADEVDGLGVARPHYGSVLDNER ddPTM_HeLa_Curcumin_4h_R1 1 SAADEVDGLGVARPHYGSVLDNER 24 1 P46940;H0YLE8;A0A0J9YXZ5 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 1 0 S(1)AADEVDGLGVARPHYGSVLDNER 65.16 0.00017258 13812000 720.37 825.59 652.4 812.72 835.09 613.21 482.13 415.85 772.79 713.52 TRUE FALSE FALSE 663.3519544 896.9503208 676.5785179 809.35718 825.1320972 486.0233337 495.6572702 542.6407507 688.0168704 738.3147669 0.898467678 1.214861684 0.91638221 1.096222392 1.117588506 0.658287434 0.671335984 0.734972095 0.931874725 1 9.528092204 -5.249478262 24.99307251 0.989135555 0.686512223 0.69796589 0.099602172 363.9971522 760580.0476 0.014684066 0.037115696 5.63E-06 5.249478262 -0.302623332 (ac)S(ph)ASAPAAEGEGTPTQPASEKEPEMPGPR ddPTM_HeLa_Curcumin_4h_R1 1 SASAPAAEGEGTPTQPASEKEPEMPGPR 28 1 A0A494C198;B4DFG0;H0Y993;P35659;D6R9L5;H0Y8X0;P35659-2 A0A494C198 DEK Protein DEK 1 0 S(0.432)AS(0.432)APAAEGEGT(0.132)PT(0.003)QPASEKEPEMPGPR 83.059 2.80E-08 16336000 1875.4 2348.2 1961.3 1694.4 2708.7 2264.6 1805.6 1708.6 1868.1 1735.2 TRUE FALSE FALSE 1726.960111 2551.167945 2033.987503 1687.389022 2676.400522 1794.896433 1856.260276 2229.544275 1663.174104 1795.498071 0.961827884 1.420869221 1.132826337 0.939788825 1.49061732 0.999664919 1.033841421 1.241741392 0.926302362 1 10.81016839 (ac)S(ph)DAAVDTSSEITTK ddPTM_HeLa_Curcumin_4h_R1 4 SDAAVDTSSEITTK 14 0 B8ZZQ6;P06454-2;P06454 B8ZZQ6 PTMA "Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1" 1 0 S(1)DAAVDTSSEITTK;S(1)DAAVDTSSEITTK;S(0.998)DAAVDT(0.001)S(0.001)SEITTK;S(1)DAAVDTSSEITTK ;;; 155.11 1.79E-29 516626000 14309.4 11087.9 12439.6 12797 12156.9 15236.4 13682.9 11048.5 14342.3 12516.3 TRUE FALSE FALSE 13176.79589 12046.28867 12900.62252 12744.0494 12011.93691 12076.19889 14066.80535 14417.13679 12768.98557 12951.24049 1.017415737 0.930126244 0.99609165 0.984002221 0.927473852 0.932435692 1.086135753 1.113185783 0.985927609 1 13.66080267 -4.632925296 6.525221496 0.990496621 1.106183837 0.663202003 0.034644212 0.107962068 5.661270805 0.005468629 0.020945461 2.33E-05 4.632925296 0.115687216 MKS(ph)SSSVTTSETQPCTPSSSDYSDLQR ddPTM_HeLa_Curcumin_4h_R1 1 MKSSSSVTTSETQPCTPSSSDYSDLQR 27 1 P50552;K7EM16 P50552 VASP Vasodilator-stimulated phosphoprotein 1 0 MKS(0.136)S(0.136)S(0.136)S(0.136)VT(0.136)T(0.136)S(0.136)ET(0.048)QPCTPSSSDYSDLQR 65.387 0.0022075 8705100 725.1 602.7 562.69 683.01 676 1790 2037.8 1119.2 791.17 635.65 TRUE FALSE FALSE 667.7075699 654.7947024 583.5437864 680.1838856 667.9391415 1418.733823 2094.975184 1460.438928 704.3806304 657.7387902 1.015156138 0.995523926 0.887196855 1.034124634 1.01550821 2.1569867 3.185117276 2.22039349 1.070912406 1 9.361370946 -5.144484761 3.258274329 0.997066705 2.704182663 0.906069048 0.227780793 0.042148571 0.837050635 0.027527725 0.07885522 7.17E-06 5.144484761 1.707115958 up (ac)S(ph)DFDEFER ddPTM_HeLa_Curcumin_4h_R1 1 SDFDEFER 8 0 P26368;P26368-2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 1 0 S(1)DFDEFER 151.29 3.29E-10 469420000 435.55 283.41 425.45 304.97 179.65 214.88 191.53 0 301.24 228.99 TRUE FALSE FALSE 401.0757579 307.9066975 441.2175513 303.7081149 177.5077911 170.3114658 196.9038163 0 268.1947257 236.9473855 1.692678555 1.299472864 1.86209082 1.281753392 0.749144333 0.718773349 0.831002275 0 1.131874594 1 7.888422932 -5.685697945 2.787764645 1.377673098 0.561804447 0.624473302 0.309323543 0.161983464 2.549213908 0.052915197 0.113058971 2.06E-06 5.685697945 -0.81586865 (ac)S(ph)DKPDMAEIEKFDK ddPTM_HeLa_Curcumin_4h_R1 1 SDKPDMAEIEKFDK 14 2 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 1 0 S(1)DKPDMAEIEKFDK 75.566 0.0020673 100600000 6907.4 5131.2 5596 5809.7 5440.6 6922.9 5063.6 4283.9 6019.9 5885.7 TRUE FALSE FALSE 6360.672001 5574.718064 5803.392683 5785.661001 5375.724398 5487.012503 5205.670988 5590.041389 5359.532031 6090.227637 1.044406282 0.91535463 0.952902425 0.949990927 0.882680372 0.900953598 0.854758032 0.917870681 0.880021627 1 12.57228044 -6.672154097 0.959339019 1.020507597 0.889864385 0.03202787 0.054349889 0.194282865 0.357312201 0.006668199 0.011055137 2.13E-07 6.672154097 -0.130643212 (ac)S(ph)DNDDIEVES(ph)DADKR ddPTM_HeLa_Curcumin_4h_R1 3 SDNDDIEVESDADKR 15 1 A0A494C130;Q6V3B1;G3V563;G3V2R5;P61244-2 A0A494C130 MAX Protein max 2 0 S(1)DNDDIEVES(1)DADKR;S(1)DNDDIEVES(1)DADKR;S(1)DNDDIEVES(1)DADKR ;; 115.8 0.00054285 63160000 6476.9 5808.1 6426.9 6675.7 6628.7 7870.4 6695.7 5238.5 6536 5758 TRUE FALSE FALSE 5964.246531 6310.126284 6665.086568 6648.077722 6549.657082 6237.990322 6883.563321 6835.694535 5819.017152 5958.090071 1.001033294 1.059085413 1.118661599 1.115806851 1.099288027 1.046978184 1.155330524 1.147296273 0.976658138 1 12.54063422 -7.034674252 2.562359205 1.000208821 1.112302888 0.780349585 0.028722057 0.096230867 1.255945939 0.00485611 0.006240539 9.23E-08 7.034674252 0.112094068 (ac)S(ph)DNDDIEVES(ph)DEEQPR ddPTM_HeLa_Curcumin_4h_R1 2 SDNDDIEVESDEEQPR 16 0 G3V5L1;P61244-6;P61244-5;P61244-3;P61244-4;P61244 G3V5L1 MAX Protein max 2 0 S(1)DNDDIEVES(1)DEEQPR;S(1)DNDDIEVES(1)DEEQPR ; 203.92 2.36E-65 16349700 59.145 66.602 257.26 188.708 0 151.61 63.249 0 59.317 53.377 TRUE FALSE FALSE 54.46361084 72.35878011 266.7942819 187.9271763 0 120.164377 65.02359671 0 52.8100735 55.23184678 0.986090707 1.310091629 4.830442896 3.402514804 0 2.175635689 1.177284493 0 0.956152593 1 5.787428462 -4.315279744 4.182565344 1.459871279 1.05E-16 0.099202499 1.360490137 0.419013607 13.90263265 0.199452156 1.575780524 4.84E-05 4.315279744 -1.459871279 (ac)S(ph)DNDDIEVESDADKR ddPTM_HeLa_Curcumin_4h_R1 3 SDNDDIEVESDADKR 15 1 A0A494C130;Q6V3B1;G3V563;G3V2R5;P61244-2 A0A494C130 MAX Protein max 1 0 S(1)DNDDIEVESDADKR;S(1)DNDDIEVESDADKR;S(1)DNDDIEVESDADKR ;; 103.91 0.00044765 471117000 3437.35 3087.15 3361.83 3430.48 3387.58 3734.39 3319.83 3360.88 4253.66 3447.23 TRUE FALSE FALSE 3165.28012 3353.98949 3486.422377 3416.285583 3347.185321 2959.835419 3412.975495 4385.59684 3787.04414 3567.020986 0.887373563 0.940277476 0.977404504 0.957741935 0.938369955 0.829777966 0.956813966 1.229484452 1.061682607 1 11.80050399 -4.265559208 5.482943369 0.939886826 1.239498457 0.66499723 0.059242958 0.057308263 6.577385782 0.007486307 0.064102543 5.43E-05 4.265559208 0.299611631 (ac)S(ph)DNGELEDKPPAPPVR ddPTM_HeLa_Curcumin_4h_R1 1 SDNGELEDKPPAPPVR 16 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 0 S(1)DNGELEDKPPAPPVR 58.831 0.00096027 6442800 2264.3 1896.4 2039.5 2287.9 1976.4 2357.1 1670.7 1210 2468.3 1797.7 TRUE FALSE FALSE 2085.078266 2060.316366 2115.085664 2278.433276 1952.832721 1868.21089 1717.575346 1578.92343 2197.533665 1860.169941 1.120907407 1.107595774 1.137038943 1.224852217 1.049814147 1.004322696 0.923343243 0.848806012 1.181361776 1 10.86121871 -4.781622748 1.741812902 1.080568699 0.852462786 0.642392306 0.066562956 0.256502779 1.364558257 0.010835978 0.069505228 1.65E-05 4.781622748 -0.228105912 (ac)S(ph)DQDHSMDEMTAVVK ddPTM_HeLa_Curcumin_4h_R1 5 SDQDHSMDEMTAVVK 15 0 H3BUU5;P08047-3;P08047 H3BUU5 SP1 Transcription factor Sp1 1 0 S(0.853)DQDHS(0.147)MDEMTAVVK;S(0.827)DQDHS(0.172)MDEMTAVVK;S(0.907)DQDHS(0.091)MDEMT(0.002)AVVK;S(0.796)DQDHS(0.201)MDEMT(0.003)AVVK;S(0.895)DQDHS(0.103)MDEMT(0.002)AVVK ;;;; 98.353 1.56E-51 80120400 10351.2 6813.73 8418.54 8474.2 9618.16 12099.6 10643.2 7821.5 11086.9 8099.3 TRUE FALSE FALSE 9531.891597 7402.67846 8730.538498 8439.136006 9503.469724 9590.006569 10941.81955 10206.23934 9870.694808 8380.750072 1.137355429 0.883295456 1.041737127 1.006966672 1.133964101 1.14428977 1.30558953 1.217819319 1.177781788 1 13.03286365 -5.170914943 1.710346664 1.046586073 1.261102045 0.513849294 0.081156905 0.225949938 1.237990695 0.011709475 0.044100084 6.75E-06 5.170914943 0.214515972 (ac)S(ph)DQEAKPSTEDLGDK ddPTM_HeLa_Curcumin_4h_R1 2 SDQEAKPSTEDLGDK 15 1 B8ZZN6;B8ZZJ0;B9A032;P63165 B8ZZN6 SUMO1 Small ubiquitin-related modifier 1 1 0 S(0.995)DQEAKPS(0.004)T(0.001)EDLGDK;S(0.996)DQEAKPS(0.002)T(0.003)EDLGDK ; 74.698 0.0044165 119645000 6065.9 5057.5 6130.9 6041.3 6701.7 6508.1 6630.9 5053.2 5421.4 5001.2 TRUE FALSE FALSE 5585.777614 5494.647764 6358.116547 6016.302701 6621.786605 5158.246699 6816.945208 6593.897418 4826.685984 5174.991328 1.079379126 1.061769463 1.228623614 1.162572519 1.279574435 0.996764317 1.317286306 1.274185211 0.932694507 1 12.33734073 -1.000000024 0.0977496 0.87826457 2.022806147 0.543193431 0.088049845 73.08858421 0.511379301 0.721166577 11.26671313 0.099999994 1.000000024 1.144541577 (ac)S(ph)DQEAKPSTEDLGDKK ddPTM_HeLa_Curcumin_4h_R1 1 SDQEAKPSTEDLGDKK 16 2 B8ZZN6;B8ZZJ0;B9A032;P63165 B8ZZN6 SUMO1 Small ubiquitin-related modifier 1 1 0 S(1)DQEAKPSTEDLGDKK 71.558 0.006132 55068000 11111 10045 10279 10548 11915 11605 11677 9241.8 9754.1 8900.8 TRUE FALSE FALSE 10231.55263 10913.24504 10659.94878 10504.35517 11772.92141 9197.992185 12004.62519 12059.58228 8684.099634 9210.102137 1.110905446 1.184921174 1.157419171 1.140525372 1.278261764 0.998685145 1.303419334 1.309386378 0.942888527 1 13.16900144 -1.000000048 0.038270935 0.430928615 2.324379259 0.559113888 0.082941975 418.9886824 1.235383821 17.36711387 52.94185954 0.099999989 1.000000048 1.893450643 (ac)S(ph)DQQLDCALDLMR ddPTM_HeLa_Curcumin_4h_R1 1 SDQQLDCALDLMR 13 0 B1AK87;P47756-2;P47756;B1AK85;A0A6I8PIN8 B1AK87 CAPZB F-actin-capping protein subunit beta 1 0 S(1)DQQLDCALDLMR 106.4 0.0019622 1484600 75.033 0 62.427 219.92 0 219.85 0 0 141.79 169.79 TRUE FALSE FALSE 69.09405888 0 64.74059954 219.0100293 0 174.2506318 0 0 126.2359917 175.6901899 0.393272151 0 0.368492968 1.246569484 0 0.991806269 0 0 0.718514744 1 7.456889827 -9.064470331 0.793721577 1.011487223 0.388767963 0.160498969 0.421646731 0.768709759 0.862113904 0.288196607 0.081623615 8.62E-10 9.064470331 -0.62271926 (ac)S(ph)DS(ph)GEQNYGERESRSAS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SDSGEQNYGERESRSASR 18 2 P62995 P62995 TRA2B Transformer-2 protein homolog beta 3 0 S(0.994)DS(0.995)GEQNY(0.013)GERES(0.145)RS(0.125)AS(0.727)R 46.356 0.0068996 3839000 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)S(ph)DSDLGEDEGLLSLAGK ddPTM_HeLa_Curcumin_4h_R1 1 SDSDLGEDEGLLSLAGK 17 0 A0A0A6YYL0;H0YKN5;Q9GZN2-2;Q9GZN2 A0A0A6YYL0 TGIF2-C20orf24;TGIF2 Homeobox protein TGIF2 1 0 S(0.5)DS(0.5)DLGEDEGLLSLAGK 117.98 2.97E-35 0 1312.7 902.2 1224.6 950.78 1038.3 1357.7 819.08 516.2 1300.1 1039 TRUE FALSE FALSE 1208.79841 980.1821479 1269.984753 946.8459243 1025.918951 1076.097716 842.0611804 673.5870037 1157.482283 1075.105173 1.124353636 0.91170815 1.181265597 0.880700743 0.954249851 1.000923205 0.783236098 0.626531265 1.076622373 1 10.07026208 -3.733209488 0.648733277 1.051021698 3.61E-13 0.69105577 0.086748554 2.259685566 0.407785572 0.01493501 2.05896599 0.000184838 3.733209488 -1.051021698 (ac)S(ph)DSGEQNYGER ddPTM_HeLa_Curcumin_4h_R1 2 SDSGEQNYGER 11 0 P62995;P62995-2 P62995 TRA2B Transformer-2 protein homolog beta 1 0 S(1)DSGEQNYGER;S(0.999)DS(0.001)GEQNYGER ; 185.81 1.84E-24 138880000 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)S(ph)DTAVADTRR ddPTM_HeLa_Curcumin_4h_R1 2 SDTAVADTRR 10 1 A0A087X0R6;Q9UMY4-3;Q9UMY4;Q9UMY4-1 A0A087X0R6 SNX12 Sorting nexin-12 1 0 S(0.94)DT(0.06)AVADTRR;S(0.979)DT(0.021)AVADTRR ; 95.815 0.00076968 18350600 120 256.72 173.47 120.95 226.6 48.217 133.28 70.048 326.46 185.62 TRUE FALSE FALSE 110.5018734 278.9097329 179.8989508 120.4495409 223.897943 38.21625068 137.0194781 91.40531274 290.6481548 192.0702812 0.575319996 1.452123312 0.93663085 0.627111806 1.165708415 0.19897014 0.713381983 0.475895137 1.513238555 1 7.585490499 -5.260228765 24.99096703 0.863775941 0.487812392 0.293514811 0.340095979 113.5656854 2344321.272 0.040807592 0.098002362 5.49E-06 5.260228765 -0.375963548 (ac)S(ph)DVEENNFEGR ddPTM_HeLa_Curcumin_4h_R1 2 SDVEENNFEGR 11 0 Q13595;F8WEH2 Q13595 TRA2A Transformer-2 protein homolog alpha 1 0 S(1)DVEENNFEGR;S(1)DVEENNFEGR ; 113.62 0.0028062 27712000 1683.55 1595.4 1596.58 1612.4 1309.49 2885.4 2165.88 1071.27 1863.61 1443.51 TRUE FALSE FALSE 1550.295241 1733.299267 1655.750659 1605.728316 1293.875187 2286.935515 2226.648764 1397.895291 1659.176646 1493.671865 1.037908846 1.16042841 1.108510308 1.075020795 0.866237905 1.531082943 1.4907215 0.935878438 1.110803975 1 10.54464753 -5.264768781 24.98949384 1.031863674 1.336377013 0.343765739 0.167664317 196.840303 1477431.392 0.022174783 0.051578936 5.44E-06 5.264768781 0.304513339 (ac)S(ph)DVEENNFEGRES(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 SDVEENNFEGRESR 14 1 Q13595 Q13595 TRA2A Transformer-2 protein homolog alpha 2 0 S(1)DVEENNFEGRES(1)R;S(1)DVEENNFEGRES(1)R ; 109.1 0.001721 81633000 450.43 292.67 388.68 239.57 383.99 389.97 320.31 140.19 271.37 305.44 TRUE FALSE FALSE 414.7779902 317.9670907 403.0848227 238.5787228 379.41117 309.0858261 329.2970365 182.9332856 241.6013899 316.0540173 1.31236424 1.006052995 1.27536687 0.754866921 1.200463052 0.977952531 1.041901126 0.578803862 0.764430688 1 8.304027342 -3.938467186 1.24849187 1.121772474 1.23E-30 0.260798367 0.193797333 2.014369409 1.550236886 0.024859699 3.516639009 0.000115221 3.938467186 -1.121772474 (ac)S(ph)EGESQTVLSSGSDPK ddPTM_HeLa_Curcumin_4h_R1 4 SEGESQTVLSSGSDPK 16 0 F8W6G1;Q9UHY1;C9JDW7;C9JHZ6 F8W6G1 NRBP1 Nuclear receptor-binding protein 1 0 S(0.923)EGES(0.076)QTVLSSGSDPK;S(0.985)EGES(0.013)QT(0.001)VLSSGSDPK;S(0.965)EGES(0.035)QTVLSSGSDPK;S(0.627)EGES(0.373)QTVLSSGSDPK ;;; 100.4 1.59E-05 88848600 15318.6 13372.5 14646.6 14803.6 14316.5 19320.1 17047.5 14743.8 15212.7 14022.6 TRUE FALSE FALSE 14106.11665 14528.35931 15189.41588 14742.34663 14145.78509 15312.89348 17525.80697 19239.11675 13543.90487 14509.88431 0.972172924 1.00127327 1.046832322 1.016020963 0.974906815 1.055342217 1.207852978 1.325931782 0.93342611 1 13.8247484 -4.63338747 1.777969452 0.993329353 1.342113239 0.937531058 0.028747734 0.067062001 0.340435589 0.003587545 0.030777386 2.33E-05 4.63338747 0.348783886 (ac)S(ph)EKSVEAAAELSAK ddPTM_HeLa_Curcumin_4h_R1 3 SEKSVEAAAELSAK 14 1 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 1 0 S(0.929)EKS(0.071)VEAAAELSAK;S(0.817)EKS(0.183)VEAAAELSAK;S(0.869)EKS(0.131)VEAAAELSAK ;; 72.652 1.24E-06 261001000 8517.1 7148.2 6304.2 7178.8 6725.9 7924.3 6967.4 6580.2 8661.3 7512.6 TRUE FALSE FALSE 7842.962548 7766.058556 6537.839198 7149.096028 6645.698035 6280.710855 7162.886492 8586.472688 7711.17706 7773.662291 1.00891475 0.999021859 0.84102434 0.919656111 0.854899247 0.80794748 0.921430109 1.10455952 0.991961931 1 12.92437872 -6.834893392 9.623719593 1.004073761 0.902444396 0.26014746 0.075282954 0.322278524 39.61883281 0.0119595 0.015731578 1.46E-07 6.834893392 -0.101629365 (ac)S(ph)ETAPAAPAAAPPAEK ddPTM_HeLa_Curcumin_4h_R1 1 SETAPAAPAAAPPAEK 16 0 P16403 P16403 HIST1H1C Histone H1.2 1 0 S(0.5)ET(0.5)APAAPAAAPPAEK 64.827 0.00046631 34063000 7279.1 4931 5855 7342.8 6332.4 7919.6 6975.2 6429.5 7461.9 4948.3 TRUE FALSE FALSE 6702.951554 5357.213668 6071.991451 7312.417439 6256.890266 6276.985688 7170.905339 8389.824952 6643.348239 5120.253057 1.309105523 1.046279082 1.185877218 1.428135945 1.221988483 1.225913176 1.400498229 1.6385567 1.297464826 1 12.3219994 -1 0.077563147 0.772372442 2.589492677 0.352581782 0.142611609 121.4145202 0.695240584 2.610410439 23.85932489 0.1 1 1.817120235 (ac)S(ph)ETAPAAPAAAPPAEKAPVK ddPTM_HeLa_Curcumin_4h_R1 3 SETAPAAPAAAPPAEKAPVK 20 1 P16403 P16403 HIST1H1C Histone H1.2 1 0 S(0.5)ET(0.5)APAAPAAAPPAEKAPVK;S(0.5)ET(0.5)APAAPAAAPPAEKAPVK;S(0.5)ET(0.5)APAAPAAAPPAEKAPVK ;; 84.753 0.00017068 52359700 16552 9876.7 9778.7 13898.2 9001 17027.9 12157.4 10893.9 21869.2 14947.6 TRUE FALSE FALSE 15241.89173 10730.39794 10141.10722 13840.69293 8893.668954 13496.1216 12498.50392 14215.39996 19470.20347 15467.02799 0.985444117 0.693759522 0.655659719 0.894851483 0.575008267 0.872573684 0.808074048 0.919077665 1.258819955 1 13.91690839 -7.276602348 23.34935383 0.993126413 0.771660789 0.496502747 0.133159085 190.8981179 293961.9705 0.016712718 0.019159111 5.29E-08 7.276602348 -0.221465624 (ac)S(ph)ETAPAAPAAAPPAEKAPVKK ddPTM_HeLa_Curcumin_4h_R1 1 SETAPAAPAAAPPAEKAPVKK 21 2 P16403 P16403 HIST1H1C Histone H1.2 1 0 S(0.5)ET(0.5)APAAPAAAPPAEKAPVKK 76.526 0.00010622 0 2272.5 1327.3 1338.5 1702.8 1374.2 2480.4 1663.3 1291.7 2928.9 2052.4 TRUE FALSE FALSE 2092.629227 1442.025898 1388.105987 1695.754265 1357.813563 1965.93708 1709.967721 1685.533384 2607.606998 2123.720747 0.985359883 0.679009187 0.653619827 0.798482695 0.639355981 0.925704136 0.805175409 0.793669971 1.227848342 1 11.05237836 -7.275618934 23.70318571 0.993086632 0.75797653 0.613053865 0.109404121 175.0282633 292584.5016 0.013709836 0.015723973 5.30E-08 7.275618934 -0.235110101 (ac)S(ph)ETAPAAPAAPAPAEKTPVK ddPTM_HeLa_Curcumin_4h_R1 5 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 1 0 S(0.5)ET(0.5)APAAPAAPAPAEKTPVK;S(0.5)ET(0.5)APAAPAAPAPAEKTPVK;S(0.5)ET(0.5)APAAPAAPAPAEKTPVK;S(0.5)ET(0.5)APAAPAAPAPAEKTPVK;S(0.5)ET(0.5)APAAPAAPAPAEKTPVK ;;;; 117.86 1.55E-05 1284574700 16673.3 9984.88 12495.92 13854 13876.1 18614.3 15321.88 7337.07 19417.2 13792.8 TRUE FALSE FALSE 15353.59071 10847.92854 12959.02979 13796.67582 13710.63657 14753.48435 15751.77072 9574.108867 17287.18174 14272.09877 1.075776657 0.760079418 0.907997485 0.966688645 0.960660152 1.033729137 1.103675848 0.670826976 1.211257154 1 13.80090988 (ac)S(ph)ETAPAETAT(ph)PAPVEKSPAKK ddPTM_HeLa_Curcumin_4h_R1 1 SETAPAETATPAPVEKSPAKK 21 2 P16401 P16401 HIST1H1B Histone H1.5 2 0 S(0.846)ET(0.156)APAET(0.133)AT(0.678)PAPVEKS(0.187)PAKK 41.275 0.0081881 0 2321.1 1802.7 2141.5 2896.8 2226.1 3030.1 2135.5 1452.1 3156.2 2450.9 TRUE FALSE FALSE 2137.382486 1958.517355 2220.865874 2884.813809 2199.555211 2401.623104 2195.416383 1894.838605 2809.972756 2536.068593 0.842793642 0.772265136 0.875712069 1.13751411 0.867309038 0.946986651 0.865677052 0.747155897 1.108003453 1 11.30837805 -9.419807008 1.190694211 0.998991448 0.883890309 0.257933034 0.107248375 0.737377565 1.895147193 0.068068421 0.017804926 3.80E-10 9.419807008 -0.115101139 (ac)S(ph)ETAPAETATPAPVEK ddPTM_HeLa_Curcumin_4h_R1 2 SETAPAETATPAPVEK 16 0 P16401 P16401 HIST1H1B Histone H1.5 1 0 S(0.922)ET(0.078)APAETATPAPVEK;S(0.978)ET(0.022)APAETATPAPVEK ; 132.05 0.00027402 41299000 13514.8 8318.1 10450.6 12611.5 12209.7 13639 12616.6 10553.1 15994 10583.7 TRUE FALSE FALSE 12445.08932 9037.079499 10837.90843 12559.31695 12064.1073 10810.11766 12970.58784 13770.69161 14239.49822 10951.48279 1.136383955 0.825192321 0.989629317 1.14681429 1.101595787 0.98709169 1.184368189 1.257427134 1.300234725 1 13.4188386 -4.601870327 4.782890028 1.047868263 1.241910276 0.225111954 0.119877653 0.156768214 6.324761329 0.013432642 0.05545866 2.50E-05 4.601870327 0.194042013 (ac)S(ph)ETAPAETATPAPVEKS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 2 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 2 0 S(0.847)ET(0.146)APAET(0.007)AT(0.001)PAPVEKS(0.999)PAK;S(0.933)ET(0.065)APAET(0.002)AT(0.001)PAPVEKS(1)PAK ; 80.406 0.0021511 43339000 10275.1 6795 9074.2 10172.8 9360.8 12251.3 9920.7 7151.7 12347.6 7949.5 TRUE FALSE FALSE 9461.814993 7382.329522 9410.497834 10130.70765 9249.178574 9710.242279 10199.04814 9332.220408 10993.09917 8225.744533 1.15026852 0.897466423 1.144029917 1.231585495 1.124418408 1.180469712 1.239893617 1.134513766 1.336426038 1 13.00593055 -6.536778933 24.99808567 1.058064972 1.182652029 0.078089612 0.112487379 189.8912061 341499.1342 0.012376329 0.017507169 2.91E-07 6.536778933 0.124587057 (ac)S(ph)ETAPAETATPAPVEKSPAK ddPTM_HeLa_Curcumin_4h_R1 7 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 1 0 S(0.951)ET(0.049)APAETATPAPVEKSPAK;S(0.371)ET(0.047)APAET(0.167)AT(0.36)PAPVEKS(0.055)PAK;S(0.838)ET(0.041)APAET(0.002)AT(0.003)PAPVEKS(0.116)PAK;S(0.778)ET(0.198)APAET(0.009)AT(0.003)PAPVEKS(0.012)PAK;S(0.868)ET(0.044)APAET(0.002)AT(0.084)PAPVEKS(0.002)PAK;S(0.915)ET(0.035)APAET(0.018)AT(0.001)PAPVEKS(0.03)PAK;S(0.505)ET(0.039)APAET(0.358)AT(0.055)PAPVEKS(0.043)PAK ;;;;;; 107.34 2.44E-07 7780947300 28148.1 25431.2 23470 30883.2 25326 33779 24245.6 17100.2 32821.7 23788 TRUE FALSE FALSE 25920.14818 27629.35961 24339.81885 30755.4135 25024.00399 26772.85463 24925.86628 22313.97226 29221.24163 24614.63123 1.05303825 1.122477089 0.988835405 1.249476915 1.016631277 1.087680509 1.012644311 0.906532869 1.187149275 1 14.58722851 -4.316882161 3.224054055 1.048767177 0.894398491 0.209670427 0.085763218 0.312820918 5.220706814 0.010164321 0.110832119 4.82E-05 4.316882161 -0.154368687 (ac)S(ph)ETAPAETATPAPVEKSPAKK ddPTM_HeLa_Curcumin_4h_R1 2 SETAPAETATPAPVEKSPAKK 21 2 P16401 P16401 HIST1H1B Histone H1.5 1 0 S(0.841)ET(0.03)APAET(0.076)AT(0.003)PAPVEKS(0.05)PAKK;S(0.383)ET(0.023)APAET(0.153)AT(0.153)PAPVEKS(0.288)PAKK ; 69.72 0.0002713 692065000 7453.4 4863.3 5463.7 6611.4 7255.3 8195.5 5968 4307.4 7835.8 5676.8 TRUE FALSE FALSE 6863.455525 5283.661982 5666.189528 6584.043779 7168.785286 6495.660918 6135.446018 5620.706431 6976.232344 5874.068377 1.168433032 0.899489356 0.964610754 1.120866043 1.220412298 1.105819766 1.044496867 0.956867723 1.187632131 1 12.52014434 -9.81290152 1.843097276 0.999738284 1.080985387 0 0.112435024 0.815055096 5.012256616 0.077908742 0.01611649 1.54E-10 9.81290152 0.081247103 (ac)S(ph)ETAPLAPTIPAPAEK ddPTM_HeLa_Curcumin_4h_R1 2 SETAPLAPTIPAPAEK 16 0 P16402 P16402 HIST1H1D Histone H1.3 1 0 S(0.5)ET(0.5)APLAPTIPAPAEK;S(0.5)ET(0.5)APLAPTIPAPAEK ; 80.318 0.00038086 10756300 10981.6 7431.4 9129.9 9935.6 8736.9 11570.5 10493.3 8597.5 11522.1 8695.9 TRUE FALSE FALSE 10112.39477 8073.737102 9468.262125 9894.48912 8632.718174 9170.647874 10787.71376 11218.83817 10258.15446 8998.081878 1.123838937 0.897273131 1.052253386 1.099622037 0.959395379 1.019178087 1.198890375 1.246803299 1.14003791 1 13.13540178 -4.686741072 4.792421777 1.041439403 1.233453581 0.526933271 0.070906728 0.120277287 5.000058709 0.009867907 0.039114757 2.06E-05 4.686741072 0.192014178 (ac)S(ph)FEGGDGAGPAMLATGTAR ddPTM_HeLa_Curcumin_4h_R1 4 SFEGGDGAGPAMLATGTAR 19 0 Q96B36-3 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 0 S(1)FEGGDGAGPAMLATGTAR;S(1)FEGGDGAGPAMLATGTAR;S(1)FEGGDGAGPAMLATGTAR;S(1)FEGGDGAGPAMLATGTAR ;;; 205.12 1.43E-33 25916800 2150.34 1909.598 2062.85 2381.88 2073.06 2637.02 1909.88 1180.136 2192.06 2214.33 TRUE FALSE FALSE 1980.13832 2074.655142 2139.301036 2372.024412 2048.340113 2090.072327 1963.466093 1539.954034 1951.596502 2291.277803 0.864207002 0.905457706 0.93367161 1.035240864 0.893972835 0.912186346 0.856930613 0.672093987 0.851750277 1 11.16193667 -4.001115736 1.304488697 0.936927004 0.406058141 0.664890417 0.053836111 1.15967644 1.087466619 0.008790879 0.959910909 9.97E-05 4.001115736 -0.530868863 (ac)S(ph)FLFSSR ddPTM_HeLa_Curcumin_4h_R1 2 SFLFSSR 7 0 Q9H8S9-2;Q9H8S9 Q9H8S9-2 MOB1A MOB kinase activator 1A 1 0 S(1)FLFSSR;S(1)FLFSSR ; 56.547 0.0078568 13819100 1138.95 858.58 1009.91 995.25 1271.37 1245.58 1145 1140.07 1229.8 1221.96 TRUE FALSE FALSE 1048.800906 932.7918294 1047.338153 991.1319192 1256.209743 987.2326674 1177.125618 1487.672095 1094.894017 1264.423019 0.829469956 0.737721329 0.828313102 0.783861021 0.993504329 0.780777202 0.930958707 1.176562015 0.865923825 1 10.30426349 -4.282898727 3.973851897 0.885743628 1.197426722 0.533309576 0.086673044 0.163206648 5.232920133 0.014206027 0.140658437 5.21E-05 4.282898727 0.311683094 (ac)S(ph)GDEMIFDPTMS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SGDEMIFDPTMSK 13 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 2 0 S(1)GDEMIFDPT(0.299)MS(0.701)K 52.522 0.0037959 0 616.15 374.11 604.49 583.12 558.51 721.46 987.01 432.05 501.78 483.81 TRUE FALSE FALSE 567.3810773 406.4464014 626.8929312 580.7072039 551.850133 571.8210635 1014.702844 563.7800561 446.7359894 500.6223615 1.133351446 0.811882234 1.252227186 1.159970566 1.102328173 1.142220379 2.026882781 1.126158357 0.892361236 1 8.967578924 -4.967788852 24.48807344 1.07126256 1.578529414 0.435325242 0.235681971 88.95672028 67626.91018 0.02779312 0.083378333 1.08E-05 4.967788852 0.507266854 (ac)S(ph)GDEMIFDPTMS(ph)KK ddPTM_HeLa_Curcumin_4h_R1 1 SGDEMIFDPTMSKK 14 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 2 0 S(1)GDEMIFDPT(0.33)MS(0.67)KK 77.221 0.0034989 5043600 1088.7 822 923.34 1141.7 995.76 2044.2 1749.8 886.27 1004.5 633.21 TRUE FALSE FALSE 1002.528246 893.0500172 957.5597927 1136.975948 983.8862124 1620.209877 1798.894679 1156.489643 894.3088631 655.2140004 1.530077571 1.362989827 1.461445867 1.735274196 1.501625746 2.472794959 2.745507083 1.765056367 1.364911102 1 9.355822374 -5.227370377 0.272939069 1.04262492 2.971519334 0.561029688 0.333677422 2.565584631 0.228938741 0.224166872 1.608999343 5.92E-06 5.227370377 1.928894414 (ac)S(ph)GDEMIFDPTMSK ddPTM_HeLa_Curcumin_4h_R1 18 SGDEMIFDPTMSK 13 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 0 S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK;S(1)GDEMIFDPTMSK ;;;;;;;;;;;;;;;;; 117.67 0.00052693 2815362800 128938.3 103546.8 112571.5 122602.9 118219.8 140826 117306.1 108664.9 132121.6 107228.1 TRUE FALSE FALSE 118732.6975 112496.924 116743.4988 122095.6017 116810.1061 111617.1002 120597.3935 141796.3278 117628.191 110954.2685 1.07010482 1.013903526 1.052176725 1.100413741 1.052777038 1.005973918 1.086910806 1.277970913 1.06015021 1 16.75960564 -4.284146349 3.061330807 1.038551649 1.309468507 0.843190823 0.029969724 0.106379096 1.519975105 0.004874647 0.067600004 5.20E-05 4.284146349 0.270916857 (ac)S(ph)GDEMIFDPTMSKK ddPTM_HeLa_Curcumin_4h_R1 2 SGDEMIFDPTMSKK 14 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 0 S(1)GDEMIFDPTMSKK;S(1)GDEMIFDPTMSKK ; 54.471 0.0066042 773200000 14692.1 11331.9 11989.4 13992.1 10264.2 15362.6 11608.5 10118.9 15753.2 13136.3 TRUE FALSE FALSE 13529.20478 12311.37894 12433.73771 13934.2044 10141.80612 12176.22359 11934.20327 13204.10603 14025.11337 13592.78545 0.99532247 0.905728924 0.914730668 1.025117659 0.74611684 0.895785756 0.877980699 0.971405462 1.03180569 1 13.7305535 -6.981862084 0.921853509 1.00101559 0.890481378 0.312182611 0.068588376 0.44070119 0.742872214 0.013857803 0.019252101 1.04E-07 6.981862084 -0.110534212 (ac)S(ph)GDGATEQAAEYVPEK ddPTM_HeLa_Curcumin_4h_R1 1 SGDGATEQAAEYVPEK 16 0 Q12996;E9PJ06;Q12996-3;Q12996-2 Q12996 CSTF3 Cleavage stimulation factor subunit 3 1 0 S(0.995)GDGAT(0.005)EQAAEYVPEK 96.163 0.00011134 0 2123.5 1936.9 1855.9 1934.8 1911.5 2214.5 1908.8 2184.8 2024.2 1706.1 TRUE FALSE FALSE 1955.422734 2104.317005 1924.681287 1926.79431 1888.706611 1755.187737 1962.355791 2850.935462 1802.150324 1765.386848 1.107645464 1.191986339 1.09023203 1.091428948 1.069854244 0.994222733 1.11157268 1.614906934 1.020824601 1 10.78576864 -4.264756916 4.375794351 1.065537463 1.65280891 0.896095673 0.055246854 0.050465265 2.320993868 0.008847247 0.091209557 5.44E-05 4.264756916 0.587271447 (ac)S(ph)GEDEQQEQTIAEDLVVTK ddPTM_HeLa_Curcumin_4h_R1 12 SGEDEQQEQTIAEDLVVTK 19 0 Q9UQ80;F8VR77 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 1 0 S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(0.905)GEDEQQEQT(0.095)IAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK;S(1)GEDEQQEQTIAEDLVVTK ;;;;;;;;;;; 182.02 5.80E-69 970253900 51534.72 47150.24 46352.45 48790.08 45905.97 56304.45 43431.79 47829.59 57827.69 49053.62 TRUE FALSE FALSE 47455.69253 51225.69665 48070.31257 48588.19958 45358.57129 44626.27239 44650.36914 62412.61181 51484.13708 50758.22964 0.934935928 1.009209679 0.947044704 0.95724772 0.893620042 0.879192846 0.879667582 1.229605765 1.014301276 1 15.63135413 -9.527737684 1.22993132 1.000478219 0.955796851 0.016825045 0.097026806 1.755896741 4.672450175 0.0672882 0.01538932 2.97E-10 9.527737684 -0.044681368 (ac)S(ph)GGKYVDSEGHLYTVPIR ddPTM_HeLa_Curcumin_4h_R1 1 SGGKYVDSEGHLYTVPIR 18 1 Q03135 Q03135 CAV1 Caveolin-1 1 0 S(0.832)GGKY(0.167)VDS(0.002)EGHLYTVPIR 69.188 0.0038206 16105000 2161.7 1877.1 1945.8 2657.9 1877.5 3021.7 1025.5 319.68 4038 2734.3 TRUE FALSE FALSE 1990.599164 2039.34816 2017.91306 2646.902314 1855.112039 2394.965358 1054.27277 417.1489604 3595.041503 2829.316721 0.7035618 0.720791753 0.713215684 0.935527046 0.655674928 0.846481887 0.372624515 0.147438057 1.270639471 1 11.46623797 -4.62750939 2.714097424 0.828861096 0.159539284 0.650456632 0.17679916 0.106530588 1.464914678 0.019551721 0.110612518 2.36E-05 4.62750939 -0.669321811 (ac)S(ph)IFTPTNQIR ddPTM_HeLa_Curcumin_4h_R1 1 SIFTPTNQIR 10 0 Q9Y3A5;A0A087X020;F8WE72 Q9Y3A5 SBDS Ribosome maturation protein SBDS 1 0 S(0.811)IFT(0.189)PTNQIR 107.01 0.0082672 3574200 0 0 131.66 147.14 140.8 196.97 174.21 211.68 214.74 205.43 TRUE FALSE FALSE 0 0 136.5394354 146.5311737 139.121052 156.1162017 179.0978637 276.2202575 191.1835593 212.5686772 0 0 0.642330927 0.68933568 0.654475785 0.734427121 0.842541178 1.299440074 0.899396664 1 7.731785216 -3.840815606 0.733797357 0.493599754 2.286017404 0.348174709 0.311689533 4.890438756 1.221385248 0.068549215 8.335693204 0.000144273 3.840815606 1.792417651 NDS(ph)LPVLR ddPTM_HeLa_Curcumin_4h_R1 2 NDSLPVLR 8 0 Q9GZY8-5 Q9GZY8-5 MFF Mitochondrial fission factor 1 0 NDS(1)LPVLR;NDS(1)LPVLR ; 111.52 0.01085 12827300 3944.7 2937.32 3219.49 4474.8 4705 10550.9 9753 7993.8 4883.2 4791.7 TRUE FALSE FALSE 3632.472833 3191.208852 3338.807132 4456.284463 4648.895948 8362.524407 10026.64293 10431.07282 4347.525177 4958.211218 0.732617606 0.643620998 0.673389451 0.898768581 0.937615552 1.686601082 2.022229891 2.103797592 0.876833395 1 12.27560402 -5.139926188 2.099262031 0.834834869 2.081615902 0.960836304 0.105110132 0.058471643 0.492923838 0.020834379 0.07130223 7.25E-06 5.139926188 1.246781033 up (ac)S(ph)KS(ph)ESPKEPEQLR ddPTM_HeLa_Curcumin_4h_R1 1 SKSESPKEPEQLR 13 2 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 2 0 S(0.977)KS(0.977)ES(0.045)PKEPEQLR 72.243 0.0037332 22824000 7212 6945.3 7091.1 7322.4 7098.5 7718.7 8566.1 4638 8040.5 7674.1 TRUE FALSE FALSE 6641.16259 7545.620784 7353.902404 7292.101849 7013.855024 6117.754612 8806.441712 6052.104849 7158.477266 7940.774404 0.836336893 0.950237395 0.926093858 0.918311172 0.883270909 0.770422921 1.109015477 0.762155495 0.901483521 1 12.95506399 -9.553787393 1.314019705 1.000187387 0.892698977 0.011811695 0.097917903 0.634668985 1.957909734 0.060701357 0.014239288 2.79E-10 9.553787393 -0.10748841 (ac)S(ph)KSESPKEPEQLR ddPTM_HeLa_Curcumin_4h_R1 4 SKSESPKEPEQLR 13 2 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 1 0 S(0.498)KS(0.498)ES(0.004)PKEPEQLR;S(0.84)KS(0.16)ESPKEPEQLR;S(0.875)KS(0.062)ES(0.062)PKEPEQLR;S(0.986)KS(0.014)ESPKEPEQLR ;;; 121.6 0.0005588 1153920900 19261.72 14645.62 13923.1 16566.93 11638.16 19266.28 16840.76 20129.98 26383.02 20721.29 TRUE FALSE FALSE 17737.13454 15911.52213 14439.10233 16498.38043 11499.38254 15270.23635 17313.2664 26267.51823 23488.86871 21441.35329 0.827239508 0.74209505 0.673423088 0.769465444 0.536317946 0.71218622 0.807470787 1.22508677 1.095493759 1 14.38810834 -8.458676597 0.832635016 0.983108213 0.768848986 0.249402023 0.17136731 0.651388951 0.938385127 0.06867843 0.036669649 3.48E-09 8.458676597 -0.214259228 (ac)S(ph)LDIQSLDIQCEELSDAR ddPTM_HeLa_Curcumin_4h_R1 2 SLDIQSLDIQCEELSDAR 18 0 E9PR82;E9PMI1;E9PMA9;E9PMN0;E9PIK5;E9PMJ3;E9PLZ3;E9PIM9;P13489 E9PR82 RNH1 Ribonuclease inhibitor 1 0 S(0.995)LDIQS(0.005)LDIQCEELSDAR;S(1)LDIQSLDIQCEELSDAR ; 139.78 6.42E-07 6183500 0 117.04 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 127.1564161 0 0 0 0 0 0 0 0 0 (ac)S(ph)LKLQASNVTNKNDPK ddPTM_HeLa_Curcumin_4h_R1 2 SLKLQASNVTNKNDPK 16 2 Q9UKM9-2;Q9UKM9;Q5QPM0;Q5QPM1;Q5QPL9;Q5QPM2 Q9UKM9-2 RALY RNA-binding protein Raly 1 0 S(0.694)LKLQAS(0.305)NVT(0.001)NKNDPK;S(0.983)LKLQAS(0.011)NVT(0.006)NKNDPK ; 58.071 0.015662 33330000 1755.2 1380.71 1187.69 1514.08 1113.78 1847.58 1627.39 1698.03 2268.2 2044.33 TRUE FALSE FALSE 1616.274068 1500.05242 1231.706836 1507.815138 1100.498901 1464.371081 1673.050184 2215.75153 2019.384135 2115.370315 0.764061997 0.709120483 0.58226535 0.712790157 0.520239361 0.692252827 0.790901797 1.047453259 0.954624408 1 11.04669453 -8.67768919 0.761777723 0.990279794 0.713607635 0.35795928 0.132766096 0.498275636 0.575076802 0.072234403 0.029846896 2.10E-09 8.67768919 -0.276672158 (ac)S(ph)LSHLYR ddPTM_HeLa_Curcumin_4h_R1 2 SLSHLYR 7 0 Q9UBB9;F6XM96;F6UKU9;F6SQZ1;F6UQ07 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 1 0 S(1)LSHLYR;S(1)LSHLYR ; 77.374 0.013011 5938800 1211.66 1665.1 1039.65 1195.16 907.65 1308.83 1092 1132.9 1284.27 1007.96 TRUE FALSE FALSE 1115.755832 1809.023824 1078.180344 1190.214745 896.8268666 1037.363904 1122.638581 1478.315995 1143.388794 1042.986535 1.069770122 1.734465176 1.033743301 1.141160221 0.859864281 0.994609105 1.076369199 1.417387421 1.096264195 1 10.02650482 -7.5057442 23.21786105 1.03078054 1.167241962 0.05437239 0.232506694 118.3477337 160370.9754 0.041168665 0.044091181 3.12E-08 7.5057442 0.136461422 (ac)S(ph)LYPSLEDLKVDK ddPTM_HeLa_Curcumin_4h_R1 1 SLYPSLEDLKVDK 13 1 B4DHN5;E9PBU7;O00560-2;O00560 B4DHN5 SDCBP Syntenin-1 1 0 S(0.975)LY(0.011)PS(0.013)LEDLKVDK 132.14 0.00028822 20310000 3808.3 3390.5 4399.2 4041.4 3867.6 4264.5 3130.7 2625.4 4435.6 3480.3 TRUE FALSE FALSE 3506.869037 3683.559712 4562.238222 4024.677758 3821.481396 3379.994629 3218.539016 3425.872374 3949.025777 3601.240166 0.973794825 1.022858666 1.266851976 1.117581048 1.061157051 0.938564071 0.893730734 0.9513035 1.096573845 1 11.8142781 -5.154663046 5.576949552 1.025683883 0.921580861 0.266632152 0.088316057 0.311350266 13.63927103 0.014104557 0.036812796 7.00E-06 5.154663046 -0.104103022 (ac)S(ph)QGDSNPAAIPHAAEDIQGDDR ddPTM_HeLa_Curcumin_4h_R1 1 SQGDSNPAAIPHAAEDIQGDDR 22 0 P68402-3;P68402-2;P68402-4;P68402 P68402-3 PAFAH1B2 Platelet-activating factor acetylhydrolase IB subunit beta 1 0 S(0.5)QGDS(0.5)NPAAIPHAAEDIQGDDR 74.783 2.71E-05 20388000 0 0 0 64.069 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 63.80389945 0 0 0 0 0 0 0 (ac)S(ph)QKQEEENPAEETGEEK ddPTM_HeLa_Curcumin_4h_R1 1 SQKQEEENPAEETGEEK 17 1 O43768;O43768-3;A0A1W2PRU0;A6NMQ3;Q5T5H1;O43768-2;O43768-9;O43768-4;O43768-8 O43768 ENSA Alpha-endosulfine 1 0 S(1)QKQEEENPAEETGEEK 131.06 4.29E-35 0 1722.1 1215 1509.8 1613.6 2112.5 2060.8 2238.5 1924.8 1259.8 1271.2 TRUE FALSE FALSE 1585.793968 1320.019186 1565.754516 1606.923351 2087.309817 1633.36685 2301.306285 2511.662659 1121.603092 1315.374105 1.205583994 1.003531376 1.190349202 1.221647396 1.5868564 1.241750802 1.749545073 1.909466401 0.852687526 1 10.36125746 -1 0.318174191 1.054785144 9.687583346 0.808125797 0.142891229 14.17880692 0.18086734 0.042371497 72.0764867 0.1 1 8.632798202 (ac)S(ph)QKQEEENPAEETGEEKQDTQEK ddPTM_HeLa_Curcumin_4h_R1 3 SQKQEEENPAEETGEEKQDTQEK 23 2 O43768;O43768-3;A0A1W2PRU0;A6NMQ3;Q5T5H1;O43768-2;O43768-9;O43768-4;O43768-8 O43768 ENSA Alpha-endosulfine 1 0 S(0.999)QKQEEENPAEET(0.001)GEEKQDTQEK;S(1)QKQEEENPAEETGEEKQDTQEK;S(1)QKQEEENPAEETGEEKQDTQEK ;; 104.35 2.70E-06 183149000 3757.44 3064.77 3672.12 3094.94 4152.35 4284 4709.51 4416.39 3165.26 2914.5 TRUE FALSE FALSE 3460.034659 3329.675062 3808.211998 3082.133958 4102.835938 3395.450109 4841.646176 5762.92698 2818.038897 3015.778658 1.147310546 1.104084696 1.262762434 1.022002709 1.360456586 1.125894999 1.605438172 1.910925049 0.934431607 1 11.55831483 -1 0.526718094 1.074089943 34.47658092 0.835077739 0.117473209 26.63724259 0.238024228 0.019934222 1002.114926 0.1 1 33.40249098 (ac)S(ph)QPGQKPAAS(ph)PRPR ddPTM_HeLa_Curcumin_4h_R1 1 SQPGQKPAASPRPR 14 2 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;F8W7E0;E9PSG1 P20810-6 CAST Calpastatin 2 0 S(1)QPGQKPAAS(1)PRPR 48.729 0.0087834 0 3141.1 4499.9 3100.5 3549.5 5720.5 6709.9 3365.8 2424.7 11471 3865.7 TRUE FALSE FALSE 2892.478621 4888.851305 3215.407257 3534.813109 5652.286774 5318.191104 3460.235289 3163.979868 10212.66 4000.032787 0.723113728 1.222202808 0.803845225 0.883696034 1.413060111 1.329536878 0.865051732 0.790988483 2.553144072 1 11.96579611 (ac)S(ph)RHEGVSCDACLK ddPTM_HeLa_Curcumin_4h_R1 2 SRHEGVSCDACLK 13 1 Q9P0J7 Q9P0J7 KCMF1 E3 ubiquitin-protein ligase KCMF1 1 0 S(1)RHEGVSCDACLK;S(1)RHEGVSCDACLK ; 74.944 0.0044147 36441000 3942.9 3365.6 3031.5 3136.4 3662.6 4649.6 3262.8 3434.6 4190 3418.4 TRUE FALSE FALSE 3630.815304 3656.507467 3143.850057 3123.422408 3618.925887 3685.220548 3354.345387 4481.793729 3730.367483 3537.189146 1.026469085 1.033732525 0.888798966 0.883023859 1.023107823 1.04185001 0.948308176 1.267049497 1.054613516 1 11.78838765 -4.255122358 24.89488337 0.996723679 1.267049625 0.662037017 0.059387187 319.6327333 1259610.191 0.008201669 0.101307909 5.56E-05 4.255122358 0.270325946 (ac)S(ph)RLSWGYR ddPTM_HeLa_Curcumin_4h_R1 2 SRLSWGYR 8 1 Q8N1Q1 Q8N1Q1 CA13 Carbonic anhydrase 13 1 0 S(1)RLSWGYR;S(1)RLSWGYR ; 100.07 0.0035886 43131000 1286.33 1388.24 1313.28 1128.1 1197.15 1235 822.05 808.23 1239.68 1236.31 TRUE FALSE FALSE 1184.515623 1508.23328 1361.951312 1123.432221 1182.874768 978.8470787 845.1145106 1054.655606 1103.690206 1279.27168 0.925929684 1.178978088 1.064630237 0.878181107 0.924647036 0.765159656 0.660621605 0.824418786 0.862748877 1 10.32110697 -5.428055803 1.70966209 0.986899067 0.732878207 0.564987913 0.092934948 0.198244571 1.119981966 0.013479802 0.039947452 3.73E-06 5.428055803 -0.25402086 SVST(ph)PSEAGSQDSGDGAVGSR ddPTM_HeLa_Curcumin_4h_R1 3 SVSTPSEAGSQDSGDGAVGSR 21 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5;E7ET01;E7ERR6;E7EUM4;E7ERH4 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 0 SVS(0.027)T(0.971)PS(0.002)EAGSQDSGDGAVGSR;S(0.035)VS(0.204)T(0.754)PS(0.002)EAGS(0.001)QDS(0.004)GDGAVGSR;SVS(0.003)T(0.949)PS(0.048)EAGSQDSGDGAVGSR ;; 277.64 1.54E-72 111388000 4454.2 3916.3 3486.46 3999 3967.4 8350.4 8250.4 5873 4590.4 3407.44 TRUE FALSE FALSE 4101.64537 4254.807521 3615.671275 3982.453198 3920.091346 6618.432912 8481.884019 7663.650664 4086.844605 3525.848286 1.163307391 1.206747193 1.025475568 1.129502144 1.111815095 1.877117894 2.405629321 2.17356223 1.159109602 1 11.78375468 -5.124147819 2.739857855 1.08752187 2.285383912 0.968384934 0.087809165 0.032397078 0.466394853 0.013388449 0.041142607 7.51E-06 5.124147819 1.197862042 up (ac)S(ph)SILPFTPPIVKR ddPTM_HeLa_Curcumin_4h_R1 1 SSILPFTPPIVKR 13 1 P84022 P84022 SMAD3 Mothers against decapentaplegic homolog 3 1 0 S(0.474)S(0.474)ILPFT(0.053)PPIVKR 66.962 0.0029783 0 1772.5 1041.2 879.61 1418.5 940.08 1532.9 1004.5 767.76 2115.4 1846.1 TRUE FALSE FALSE 1632.204755 1131.196689 912.2091204 1412.630623 928.87016 1214.959261 1032.683567 1001.84649 1883.345912 1910.251838 0.854444803 0.592171496 0.477533434 0.73949968 0.486255342 0.636020464 0.540600745 0.524457807 0.985914985 1 10.89954713 -7.399050847 1.925518118 0.9464801 0.567606277 0.833337466 0.07763304 0.091514347 0.650589855 0.014902994 0.016791052 3.99E-08 7.399050847 -0.378873823 (ac)S(ph)SNSASAANGNDSKK ddPTM_HeLa_Curcumin_4h_R1 2 SSNSASAANGNDSKK 15 1 A6NLN1;K7ES59 A6NLN1 PTBP1 1 0 S(0.329)S(0.329)NS(0.329)AS(0.012)AANGNDSKK;S(0.445)S(0.445)NS(0.111)ASAANGNDSKK ; 116.58 3.11E-09 9790000 3361.2 3612 3851.4 3209.7 3492.5 3405.8 2607.1 2159.72 4051.9 3428.9 TRUE FALSE FALSE 3095.157473 3924.205185 3994.136272 3196.419112 3450.854219 2699.398689 2680.248209 2818.208686 3607.416707 3548.05402 0.872353537 1.106016189 1.125725891 0.900893587 0.972604757 0.760811046 0.755413586 0.794297006 1.016731055 1 11.79281226 -5.26138949 24.99999893 0.964436937 0.768697839 0.61543734 0.079709493 2.859876092 1432582.296 0.012906406 0.030759132 5.48E-06 5.26138949 -0.195739097 (ac)S(ph)TEAQRVDDSPSTSGGSSDGDQR ddPTM_HeLa_Curcumin_4h_R1 1 STEAQRVDDSPSTSGGSSDGDQR 23 1 F8WF15;F8W8F0;C9J180;Q96LR5 F8WF15 UBE2E2 Ubiquitin-conjugating enzyme E2 E2 1 0 S(0.499)T(0.499)EAQRVDDS(0.001)PSTSGGSSDGDQR 98.253 1.53E-18 0 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)S(ph)TVHEILCK ddPTM_HeLa_Curcumin_4h_R1 1 STVHEILCK 9 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YNP5;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 0 S(0.5)T(0.5)VHEILCK 55.531 0.016442 59009000 8207 6330.7 7335.8 8178.1 8221.3 13926 10812 6415.9 8746.8 6365.3 TRUE FALSE FALSE 7557.40729 6877.897499 7607.671201 8144.261189 8123.266367 11037.59062 11115.35562 8372.078375 7787.297923 6586.493701 1.14740978 1.044242629 1.155041141 1.236509372 1.233321815 1.67579157 1.687598307 1.27109791 1.182313121 1 12.68529494 -5.621709084 1.685331146 1.077648232 1.555096083 0.653669577 0.13170774 0.143988767 0.817942533 0.019529823 0.050295552 2.39E-06 5.621709084 0.477447851 (ac)S(ph)TVHEILCKLSLEGDHSTPPSAYGSVK ddPTM_HeLa_Curcumin_4h_R1 2 STVHEILCKLSLEGDHSTPPSAYGSVK 27 1 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 0 S(0.461)T(0.461)VHEILCKLS(0.031)LEGDHS(0.036)T(0.011)PPSAYGSVK;S(0.286)T(0.286)VHEILCKLS(0.286)LEGDHS(0.111)T(0.029)PPSAYGSVK ; 54.605 8.12E-08 203655000 3282.3 2516.37 2230.12 2410.2 4884.9 11042 3603.7 2044.5 5796.4 2545.5 TRUE FALSE FALSE 3022.502492 2733.87381 2312.770209 2400.227231 4826.650758 8751.764731 3704.810123 2667.858638 5160.549422 2633.955936 1.147514448 1.037934528 0.878059567 0.911263244 1.832472098 3.322669378 1.406557366 1.012871401 1.959239087 1 11.3630155 -5.709879155 6.170091611 1.042846946 1.97136585 0.234353135 0.630167564 0.159379325 13.28576424 0.080518152 0.161027944 1.95E-06 5.709879155 0.928518903 (ac)S(ph)VAGGEIRGDTGGEDTAAPGR ddPTM_HeLa_Curcumin_4h_R1 2 SVAGGEIRGDTGGEDTAAPGR 21 1 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 1 0 S(1)VAGGEIRGDTGGEDTAAPGR;S(0.997)VAGGEIRGDT(0.003)GGEDTAAPGR ; 77.776 3.19E-05 25301000 459.18 405.87 249.83 448.02 491.37 557.89 519.64 423.73 530.49 489.11 TRUE FALSE FALSE 422.8354185 440.9515943 259.0889196 446.1662119 485.5107337 442.1773253 534.2196999 552.9233264 472.2965742 506.1065361 0.835467216 0.871262398 0.511925654 0.881565797 0.959305401 0.873684281 1.055547917 1.092503825 0.933195959 1 8.983297296 -4.715395082 4.736076784 0.884725121 1.082338258 0.297533643 0.127791305 0.223332437 10.74016299 0.019664715 0.076362227 1.93E-05 4.715395082 0.197613137 VEAPSLDVHMDS(ph)PDINIEGPDVK ddPTM_HeLa_Curcumin_4h_R1 2 VEAPSLDVHMDSPDINIEGPDVK 23 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VEAPSLDVHMDS(1)PDINIEGPDVK;VEAPS(0.002)LDVHMDS(0.998)PDINIEGPDVK ; 73.212 0.00078693 220837000 8219.6 5763.2 7140.8 7699.8 7970.5 15216.3 15742.2 11450.4 7892.7 5546 TRUE FALSE FALSE 7569.009987 6261.345328 7405.44433 7667.940268 7875.456993 12060.26786 16183.88376 14941.57425 7026.890557 5738.723087 1.318936264 1.09106943 1.290434164 1.336175339 1.372336123 2.101559471 2.820119305 2.603640918 1.224469355 1 12.48651405 -5.12187784 1.795673941 1.170385719 2.755549343 0.960798332 0.122073028 0.055757361 0.338181154 0.021889214 0.084032466 7.55E-06 5.12187784 1.585163624 up (ac)S(ph)VNYAAGLSPYADKGK ddPTM_HeLa_Curcumin_4h_R1 1 SVNYAAGLSPYADKGK 16 1 Q8N6T7-2;Q8N6T7;M0R0B2;M0QXA0 Q8N6T7-2 SIRT6 NAD-dependent protein deacetylase sirtuin-6 1 0 S(0.579)VNY(0.421)AAGLSPYADKGK 93.345 0.00061903 9778100 2073.8 1739.4 1610.4 2171.8 1844.8 2662.9 2545 1704.6 2525.5 1563.6 TRUE FALSE FALSE 1909.656542 1889.745985 1670.082841 2162.813667 1822.801965 2110.584523 2616.40585 2224.324693 2248.458968 1617.934984 1.180304871 1.167998717 1.03223112 1.336774153 1.126622505 1.304492791 1.617126694 1.374792384 1.389709099 1 10.65993792 -1.000000001 0.200133596 1.013336491 3.418466761 0.23320826 0.15591034 23.67910922 0.271718197 0.103853778 18.00200948 0.1 1.000000001 2.40513027 (ac)S(ph)VPAFIDISEEDQAAELR ddPTM_HeLa_Curcumin_4h_R1 1 SVPAFIDISEEDQAAELR 18 0 E9PRI2;E7ESM3;Q7L2H7 E9PRI2 EIF3M Eukaryotic translation initiation factor 3 subunit M 1 0 S(1)VPAFIDISEEDQAAELR 124.3 1.65E-06 0 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)S(ph)YDYHQNWGR ddPTM_HeLa_Curcumin_4h_R1 1 SYDYHQNWGR 10 0 Q9H2U1-3;Q9H2U1-2;Q9H2U1 Q9H2U1-3 DHX36 ATP-dependent RNA helicase DHX36 1 0 S(0.625)Y(0.375)DYHQNWGR 86.794 0.0031665 4547400 706.97 537.92 509.52 634.95 730.41 858.98 629.89 494.18 811.58 578.28 TRUE FALSE FALSE 651.0125785 584.4154079 528.4032594 632.3227451 721.7003378 680.8178653 647.5630181 644.8532071 722.5517045 598.375187 1.087967203 0.976670525 0.883063454 1.056732898 1.206100041 1.137777569 1.082202324 1.077673709 1.207522839 1 9.224906541 -5.987355748 24.49593316 1.023458227 1.124629641 0.218705864 0.08444317 168.0440708 325551.9299 0.010349469 0.018751153 1.03E-06 5.987355748 0.101171415 (ac)S(ph)YGRPPPDVEGMTSLK ddPTM_HeLa_Curcumin_4h_R1 1 SYGRPPPDVEGMTSLK 16 1 J3KP15;Q01130;J3QL05;Q01130-2 J3KP15 SRSF2 Serine/arginine-rich splicing factor 2 1 0 S(0.544)Y(0.456)GRPPPDVEGMTSLK 49.423 0.0078028 8404800 1749 1594 1822.2 1592.9 1778 2194.4 3137.9 1981.2 1804.8 1763.6 TRUE FALSE FALSE 1610.564804 1731.778257 1889.732335 1586.309002 1756.798511 1739.256704 3225.941029 2585.25876 1606.817955 1824.884969 0.882556891 0.948979408 1.035535043 0.869265202 0.96269 0.953077445 1.767750343 1.416669436 0.880503694 1 10.83358981 -4.771506264 24.99996123 0.946627363 1.592209877 0.885969272 0.093353977 35.37590452 87852.86661 0.011787043 0.035963304 1.69E-05 4.771506264 0.645582514 (ac)SAEVPEAASAEEQKEMEDKVT(ph)SPEKAEEAK ddPTM_HeLa_Curcumin_4h_R1 1 SAEVPEAASAEEQKEMEDKVTSPEKAEEAK 30 3 P56211 P56211 ARPP19 cAMP-regulated phosphoprotein 19 1 0 S(0.002)AEVPEAAS(0.012)AEEQKEMEDKVT(0.517)S(0.468)PEKAEEAK 44.968 0.00032547 673810000 1934.7 2600 1712.6 1894.5 1681.9 2049.8 1552.3 1100.8 2023.5 1695.5 TRUE FALSE FALSE 1781.566454 2824.732415 1776.070463 1886.661061 1661.844441 1624.648374 1595.85336 1436.428853 1801.527113 1754.418499 1.015474047 1.610067619 1.01234139 1.075376863 0.947233766 0.926032401 0.909619547 0.818749263 1.026851412 1 10.77677721 -5.469240518 1.803036523 1.06263355 0.876893346 0.239587828 0.177979716 0.536804467 3.406574591 0.028229015 0.078792698 3.39E-06 5.469240518 -0.185740204 (ac)SASAPAAEGEGT(ph)PTQPASEKEPEMPGPR ddPTM_HeLa_Curcumin_4h_R1 1 SASAPAAEGEGTPTQPASEKEPEMPGPR 28 1 A0A494C198;B4DFG0;H0Y993;P35659;D6R9L5;H0Y8X0;P35659-2 A0A494C198 DEK Protein DEK 1 0 S(0.025)AS(0.025)APAAEGEGT(0.851)PT(0.098)QPASEKEPEMPGPR 70.593 7.59E-11 20254000 2765.3 2451.1 2548.3 2355.8 3186.7 3099.8 2709.7 2013.9 2376.2 2245.3 TRUE FALSE FALSE 2546.423587 2662.962162 2642.74224 2346.052324 3148.700684 2456.866538 2785.726889 2627.928839 2115.536805 2323.324008 1.096026029 1.146186306 1.137483292 1.009782672 1.35525681 1.057479082 1.199026429 1.13110734 0.91056469 1 11.18197465 -8.28634574 0.355824885 0.977278888 1.170181013 0.396772915 0.090286043 1.310540944 0.383156407 0.102631667 0.04412241 5.17E-09 8.28634574 0.192902125 (ac)SCINLPT(ph)VLPGSPSKTR ddPTM_HeLa_Curcumin_4h_R1 1 SCINLPTVLPGSPSKTR 17 1 K7ENW5;K7ES52;K7ERJ1;K7ERV3;P04183 K7ENW5 TK1 "Thymidine kinase;Thymidine kinase, cytosolic" 1 0 SCINLPT(0.551)VLPGS(0.28)PS(0.154)KT(0.014)R 106.6 0.00034995 159100000 1443.4 900.44 850.02 959.43 576.43 1367.5 1031.3 621.94 1786.5 1601.5 TRUE FALSE FALSE 1329.153367 978.2700213 881.522489 955.4601329 569.5564487 1083.865085 1060.235502 811.5666429 1590.52542 1657.152006 0.80207088 0.590332099 0.531950289 0.576567587 0.34369596 0.654052906 0.639793754 0.489735788 0.959794523 1 10.69449023 -7.57225106 0.918206383 0.953975598 0.532447229 0.800321644 0.087489782 0.153604507 0.268514654 0.02287058 0.022898107 2.68E-08 7.57225106 -0.421528369 (ac)SCINLPTVLPGS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 SCINLPTVLPGSPSK 15 0 K7ENW5;K7ES52;K7ERJ1;K7ERV3;P04183 K7ENW5 TK1 "Thymidine kinase;Thymidine kinase, cytosolic" 1 0 SCINLPTVLPGS(0.714)PS(0.286)K;S(0.001)CINLPT(0.005)VLPGS(0.897)PS(0.098)K ; 105.39 0.00043892 30754000 4877.8 4557.7 4818.4 4780.6 5124.7 6429.9 4964 2877.1 5121 4268.1 TRUE FALSE FALSE 4491.716983 4951.647279 4996.974143 4760.819144 5063.5913 5096.26626 5103.27648 3754.314545 4559.239112 4416.416157 1.017050211 1.121191279 1.131454547 1.077982458 1.146538532 1.153937056 1.155524366 0.850081698 1.032339107 1 12.10866041 -7.323429538 5.964576547 1.007674507 1.099006308 0.130652684 0.085528838 0.25510492 18.56624413 0.013775736 0.015750412 4.75E-08 7.323429538 0.091331801 (ac)SCINLPTVLPGS(ph)PSKTR ddPTM_HeLa_Curcumin_4h_R1 1 SCINLPTVLPGSPSKTR 17 1 K7ENW5;K7ES52;K7ERJ1;K7ERV3;P04183 K7ENW5 TK1 "Thymidine kinase;Thymidine kinase, cytosolic" 1 0 SCINLPTVLPGS(0.599)PS(0.303)KT(0.098)R 114.06 0.00015797 143370000 2643.2 1447.4 1370.2 1740.1 1160.7 2909.4 1382.7 1089.9 3405.6 2228 TRUE FALSE FALSE 2433.987931 1572.506807 1420.980817 1732.899927 1146.859411 2305.957644 1421.494841 1422.205493 3032.0142 2305.422834 1.055766385 0.68209041 0.616364511 0.751662516 0.497461634 1.000231979 0.616587473 0.616895726 1.315166205 1 11.17081566 -7.258705893 24.20126204 1.026334132 0.685622711 0.614372668 0.154281236 68.66386633 607923.9395 0.019495431 0.023302184 5.51E-08 7.258705893 -0.340711421 (ac)SDAAVDTS(ph)SEITTK ddPTM_HeLa_Curcumin_4h_R1 2 SDAAVDTSSEITTK 14 0 B8ZZQ6;P06454-2;P06454 B8ZZQ6 PTMA "Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1" 1 0 SDAAVDT(0.06)S(0.722)S(0.208)EIT(0.005)T(0.005)K;SDAAVDT(0.214)S(0.677)S(0.108)EIT(0.001)TK ; 105.19 0.00021129 43534000 5413.6 4481.4 4134.1 4568.4 4048 6475.7 5279.5 2416.1 5121.3 4636.7 TRUE FALSE FALSE 4985.107848 4868.752247 4287.313383 4549.497171 3999.730244 5132.566824 5427.628561 3152.757768 4559.506203 4797.82498 1.039034952 1.014783213 0.893595202 0.948241587 0.833654887 1.069769499 1.131268561 0.657122296 0.950327747 1 12.22816482 -6.808913853 11.56372431 1.018702701 0.935645321 0.076544918 0.123132101 1.2252471 295.2793781 0.018414177 0.024219388 1.55E-07 6.808913853 -0.08305738 (ac)SDAAVDTSS(ph)EITTK ddPTM_HeLa_Curcumin_4h_R1 1 SDAAVDTSSEITTK 14 0 B8ZZQ6;P06454-2;P06454 B8ZZQ6 PTMA "Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1" 1 0 SDAAVDT(0.052)S(0.385)S(0.543)EIT(0.01)T(0.009)K 73.91 0.0039085 28293000 863.47 853.57 705.74 751.25 735.75 974.78 704.62 424.12 1016.5 921.29 TRUE FALSE FALSE 795.1254384 927.3487874 731.8953452 748.1415266 726.9766618 772.59964 724.3897408 553.4322356 904.9924932 953.3047589 0.834072662 0.97277264 0.767745402 0.784787362 0.762585789 0.810443494 0.759872154 0.580540725 0.949321279 1 9.896793688 -2.134006272 0.091021775 1.149190571 1.10E-12 0.718270949 0.06301045 45.20560751 0.378552536 0.796458604 6.580928849 0.007345033 2.134006272 -1.149190571 (ac)SDAAVDTSSEITTK ddPTM_HeLa_Curcumin_4h_R1 2 SDAAVDTSSEITTK 14 0 B8ZZQ6;P06454-2;P06454 B8ZZQ6 PTMA "Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1" 0 0 ; ; 135.66 0.00039757 10732000 6021 5263.6 5265.6 5204.1 5545.1 6761.5 5258.5 5574.7 6850.2 5170.4 FALSE FALSE TRUE 5544.431497 5718.56213 5460.747768 5182.566813 5478.978304 5359.088682 5406.039357 7274.400367 6098.750198 5350.071015 1.03632858 1.06887593 1.020686969 0.968691219 1.024094501 1.001685523 1.010461234 1.359682955 1.139938177 1 12.38534233 -4.260773831 24.99875914 1.017023909 1.35968306 0.819917591 0.045974808 9.162439362 344076.896 0.003660385 0.029234804 5.49E-05 4.260773831 0.342659152 (ac)SDDDS(ph)RASTSSSSSSSSNQQTEKETNTPK ddPTM_HeLa_Curcumin_4h_R1 3 SDDDSRASTSSSSSSSSNQQTEKETNTPK 29 2 C9J2P0;P51965-3;P51965 C9J2P0 UBE2E1 Ubiquitin-conjugating enzyme E2 E1 1 0 S(0.057)DDDS(0.296)RAS(0.057)T(0.057)S(0.066)S(0.066)S(0.066)S(0.066)S(0.066)S(0.066)S(0.066)S(0.066)NQQT(0.001)EKETNTPK;S(0.169)DDDS(0.224)RAS(0.203)T(0.203)S(0.032)S(0.032)S(0.032)S(0.032)S(0.032)S(0.032)S(0.006)S(0.001)NQQTEKETNTPK;S(0.069)DDDS(0.287)RAS(0.06)T(0.06)S(0.06)S(0.06)S(0.06)S(0.06)S(0.079)S(0.079)S(0.103)S(0.022)NQQTEKETNTPK ;; 71.06 8.90E-10 44618700 6100 4297.8 3916.2 5255.9 2942.47 5095.9 3106.79 3547.1 7362.8 6259.8 TRUE FALSE FALSE 5617.178563 4669.282681 4061.337817 5234.152478 2907.382967 4038.952897 3193.958166 4628.594461 6555.119261 6477.327584 0.867206188 0.720865607 0.627008248 0.808072837 0.448855323 0.623552359 0.493098137 0.71458397 1.012009841 1 12.66118299 -7.191204628 0.61435843 0.980566016 0.57374663 0.729417965 0.095172341 0.233173326 0.192122407 0.026488579 0.03320972 6.44E-08 7.191204628 -0.406819386 (ac)SDEFS(ph)LADALPEHSPAK ddPTM_HeLa_Curcumin_4h_R1 1 SDEFSLADALPEHSPAK 17 0 Q8NDC0 Q8NDC0 MAPK1IP1L MAPK-interacting and spindle-stabilizing protein-like 1 0 S(0.025)DEFS(0.974)LADALPEHS(0.001)PAK 82.489 0.00013955 10302000 2023.3 2402.8 2299.9 1873 2159.9 3908.4 2608.5 3922.7 3275.7 2607.7 TRUE FALSE FALSE 1863.15367 2610.487325 2385.136317 1865.250022 2134.144603 3097.753783 2681.68749 5118.713172 2916.363905 2698.317381 0.690487221 0.967450065 0.883934682 0.691264132 0.79091682 1.14803166 0.99383694 1.89700189 1.080808331 1 11.39784434 -1.801743483 1.036480278 0.850782971 199.9999962 0.799586349 0.147147871 95.51354278 0.688891263 0.022360533 44504.20883 0.015785434 1.801743483 199.1492132 (ac)SDEFSLADALPEHS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 4 SDEFSLADALPEHSPAK 17 0 Q8NDC0 Q8NDC0 MAPK1IP1L MAPK-interacting and spindle-stabilizing protein-like 1 0 SDEFSLADALPEHS(1)PAK;S(0.002)DEFS(0.005)LADALPEHS(0.992)PAK;S(0.008)DEFS(0.083)LADALPEHS(0.909)PAK;S(0.044)DEFS(0.458)LADALPEHS(0.499)PAK ;;; 160.45 7.14E-66 147804000 13929.7 12787.6 13372.5 12402.1 12200.5 23161.9 17571.5 17679.2 16550.2 13898.2 TRUE FALSE FALSE 12827.14955 13892.90316 13868.09661 12350.7834 12055.01701 18357.86085 18064.509 23069.50669 14734.68447 14381.16142 0.891941143 0.966048761 0.964323827 0.858816826 0.838250588 1.276521438 1.256123096 1.604147678 1.024582371 1 13.81189257 -4.675387635 1.324255339 0.938109271 1.622010615 0.842149431 0.090731317 0.187395705 0.459070152 0.013022569 0.140427094 2.11E-05 4.675387635 0.683901343 (ac)SDEREVAEAATGEDAS(ph)SPPPKTEAASDPQHPAASEGAAAAAASPPLLR ddPTM_HeLa_Curcumin_4h_R1 1 SDEREVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLR 48 2 Q99536-3;Q99536;K7ERT7 Q99536-3 VAT1 Synaptic vesicle membrane protein VAT-1 homolog 1 0 S(0.034)DEREVAEAAT(0.038)GEDAS(0.278)S(0.278)PPPKT(0.278)EAAS(0.094)DPQHPAASEGAAAAAASPPLLR 47.136 6.33E-06 26537000 399.02 461.47 295.54 287.69 393.13 817.97 566.86 319.24 354.63 542.37 TRUE FALSE FALSE 367.437146 501.3574105 306.4929724 286.499615 388.4421815 648.3138016 582.764566 416.5748064 315.7279762 561.2173171 0.654714555 0.893339167 0.54612173 0.510496747 0.692142187 1.155192083 1.03839377 0.742270051 0.562577039 1 9.132415716 -2.599228316 14.60013374 0.818037733 0.788151333 0 0.219785177 0 0 0.030237276 0 0.002516354 2.599228316 -0.0298864 (ac)SDEREVAEAATGEDASS(ph)PPPKTEAASDPQHPAASEGAAAAAASPPLLR ddPTM_HeLa_Curcumin_4h_R1 1 SDEREVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLR 48 2 Q99536-3;Q99536;K7ERT7 Q99536-3 VAT1 Synaptic vesicle membrane protein VAT-1 homolog 1 0 S(0.029)DEREVAEAAT(0.079)GEDAS(0.079)S(0.368)PPPKT(0.368)EAAS(0.074)DPQHPAAS(0.001)EGAAAAAASPPLLR 41.674 4.71E-06 27291000 187.31 174.39 150.83 62.252 65.709 317.68 250.42 157.78 276.11 54.305 TRUE FALSE FALSE 172.4842159 189.4634945 156.4198925 61.99441772 64.92546309 251.789587 257.4461112 205.8863957 245.8214238 56.19209471 3.069545934 3.371710834 2.783663668 1.103258706 1.155419876 4.480872057 4.581536114 3.663974385 4.374662042 1 5.812295276 -1 0.083755988 1.53E-14 10.7382267 0 1.393312388 157.9217245 0.967828537 18.20451723 196.566318 0.1 1 10.7382267 (ac)SDK(ac)PDMAEIEKFDK ddPTM_HeLa_Curcumin_4h_R1 1 SDKPDMAEIEKFDK 14 2 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 1 SDK(0.999)PDMAEIEK(0.001)FDK 53.448 0.013197 4409400 1253.9 856.43 870.55 1071 1506.5 2686.9 1905.2 1841.5 2579 1131.3 FALSE TRUE FALSE 1154.652492 930.455993 902.8133488 1066.568486 1488.535971 2129.606652 1958.654784 2402.964873 2296.090152 1170.612591 0.986366028 0.794845366 0.771231538 0.91111995 1.271587187 1.819224113 1.673187867 2.052741352 1.96144324 1 10.19304799 -5.399099321 2.412488792 0.953093337 1.853164753 0.492888661 0.340204697 0.060719813 0.684328018 0.018502829 0.048260456 3.99E-06 5.399099321 0.900071415 (ac)SDKPDMAEIEK(ac)FDK ddPTM_HeLa_Curcumin_4h_R1 1 SDKPDMAEIEKFDK 14 2 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 1 SDKPDMAEIEK(1)FDK 77.593 1.38E-05 1540600 466.05 659.21 444.77 323.94 672.34 1204.1 807.15 548.59 1063.2 481.76 FALSE TRUE FALSE 429.1616507 716.189175 461.2535675 322.5996221 664.3227846 954.356087 829.7964567 715.8525656 946.56962 498.5011241 0.860904078 1.436685175 0.925280897 0.647139207 1.332640495 1.914451223 1.66458292 1.436009932 1.898831465 1 8.961452948 -5.530570736 6.337948795 0.956347916 1.665631284 0.23559084 0.366312504 0.060131049 10.52387086 0.030621475 0.063827747 2.95E-06 5.530570736 0.709283368 (ac)SDQQLDCALDLMR ddPTM_HeLa_Curcumin_4h_R1 2 SDQQLDCALDLMR 13 0 B1AK87;P47756-2;P47756;B1AK85;A0A6I8PIN8 B1AK87 CAPZB F-actin-capping protein subunit beta 0 0 ; ; 113.69 0.00038408 1848830 389.62 0 162.78 342.22 376.17 368.56 268.85 172.31 185.882 156.94 FALSE FALSE TRUE 358.7811659 0 168.81277 340.8039843 371.6844184 292.1165015 276.3932074 224.8465258 165.4912097 162.3936533 2.209329974 0 1.039528125 2.098628717 2.288786605 1.798817229 1.701995132 1.384577052 1.019074368 1 7.34335144 -6.250625501 24.34028753 1.406511902 1.86711183 0.215488651 0.597411656 1015.538705 2285809.821 0.106102872 0.174750534 5.62E-07 6.250625501 0.460599928 (ac)SDS(ph)GEQNYGERES(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SDSGEQNYGERESR 14 1 P62995 P62995 TRA2B Transformer-2 protein homolog beta 2 0 S(0.11)DS(0.889)GEQNY(0.001)GERES(1)R 71.545 0.00088723 0 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)SDSGEQNYGERES(ph)R ddPTM_HeLa_Curcumin_4h_R1 3 SDSGEQNYGERESR 14 1 P62995 P62995 TRA2B Transformer-2 protein homolog beta 1 0 SDSGEQNYGERES(1)R;SDSGEQNYGERES(1)R;SDSGEQNYGERES(1)R ;; 120.84 1.16E-05 76764500 93.825 494.11 250.178 427.1 139.03 205.74 0 0 287.976 359.47 TRUE FALSE FALSE 86.39865225 536.8186667 259.4498168 425.3327734 137.3721581 163.0672048 0 0 256.3857533 371.9615557 0.232278446 1.44321008 0.697517829 1.143485844 0.369318162 0.438398007 0 0 0.689280248 1 8.539009708 -5.074875852 1.675962809 0.727660198 1.99E-09 0.476843273 0.332903969 0.354603126 1.845663436 0.058227857 0.248360397 8.42E-06 5.074875852 -0.727660196 (ac)SDVEENNFEGRES(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SDVEENNFEGRESR 14 1 Q13595 Q13595 TRA2A Transformer-2 protein homolog alpha 1 0 SDVEENNFEGRES(1)R 83.087 0.0044418 4011800 284.46 155.63 266.88 132.78 303.9 223.03 191.29 269.97 333.26 343.28 TRUE FALSE FALSE 261.9446908 169.0819637 276.7708076 132.2305915 300.276191 176.7710639 196.6570826 352.2826102 296.7022118 355.2089544 0.737438309 0.476007042 0.779177451 0.372261425 0.845350848 0.497653738 0.553637739 0.991761626 0.835289224 1 8.472524141 -8.461041204 0.770443816 0.98046591 0.638530292 0.229119586 0.184461568 0.4415419 0.546274315 0.073635296 0.037291158 3.46E-09 8.461041204 -0.341935618 (ac)SESGHS(ph)QPGLYGIER ddPTM_HeLa_Curcumin_4h_R1 1 SESGHSQPGLYGIER 15 0 M0QZH1;M0QX70;M0QYR7;M0R2N0;M0QZC7;Q9H0W8-2;Q9H0W8 M0QZH1 SMG9 Protein SMG9 1 0 S(0.174)ES(0.091)GHS(0.735)QPGLYGIER 65.528 0.0018963 14497000 337.02 334.61 199.98 318.05 275.02 220.57 187.05 248.49 389.09 337.5 TRUE FALSE FALSE 310.3445114 363.5321974 207.3914347 316.7339934 271.7405661 174.8212957 192.2981196 324.2534571 346.4078005 349.2280999 0.888658477 1.040959183 0.593856665 0.90695449 0.778117701 0.500593439 0.550637591 0.928486159 0.991924191 1 8.448025837 -6.522798087 0.70733391 0.964517078 0.662891527 0.375753844 0.150378815 0.503842079 0.505509554 0.032302107 0.065364654 3.00E-07 6.522798087 -0.301625552 (ac)SESSSKSS(ph)QPLASKQEK ddPTM_HeLa_Curcumin_4h_R1 1 SESSSKSSQPLASKQEK 17 2 P17096;P17096-2;P17096-3;A0A669KAX1 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 0 S(0.066)ES(0.066)S(0.059)S(0.052)KS(0.146)S(0.608)QPLAS(0.002)KQEK 52.541 0.0096337 12449000 2429.8 1204.9 949.51 2006.3 897.79 2412.5 2389.7 2339.4 3467 2744.8 TRUE FALSE FALSE 2237.478766 1309.046187 984.6996759 1997.998462 887.0844406 1912.120306 2456.74855 3052.672291 3086.678774 2840.181596 0.787794263 0.460902285 0.346703069 0.703475604 0.312333705 0.673238749 0.864996997 1.074815883 1.086789232 1 11.47176746 -7.90837416 1.441182682 0.942266873 0.62852762 0.309783445 0.225747854 0.362663787 1.565775004 0.053257714 0.047729372 1.23E-08 7.90837416 -0.313739253 (ac)SET(ph)APAAPAAAPPAEK ddPTM_HeLa_Curcumin_4h_R1 1 SETAPAAPAAAPPAEK 16 0 P16403 P16403 HIST1H1C Histone H1.2 1 0 S(0.132)ET(0.868)APAAPAAAPPAEK 90.731 0.00034338 36983000 6221.8 4154.5 5393.6 6714.5 6551.9 7326.9 7148.6 4858.1 6465.6 4520.3 TRUE FALSE FALSE 5729.337965 4513.596468 5593.491561 6686.717178 6473.772872 5807.218349 7349.170477 6339.312326 5756.339856 4677.380089 1.224903227 0.964983897 1.195859959 1.429586019 1.384059612 1.241553656 1.571215154 1.355312634 1.230676094 1 12.19148495 -6.407196469 4.045104162 1.097839388 1.395990292 0.61516177 0.10944791 0.121602589 3.434677398 0.017928225 0.027717115 3.92E-07 6.407196469 0.298150904 (ac)SET(ph)APAAPAAPAPAEKT(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 1 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 2 0 S(0.496)ET(0.621)APAAPAAPAPAEKT(0.883)PVK 76.417 0.00020085 0 1637.3 1615.1 1419.2 2072 1787.7 1424.6 1364.1 787.27 1950.1 1440.3 TRUE FALSE FALSE 1507.705977 1754.702047 1471.7968 2063.426613 1766.382845 1129.121901 1402.372975 1027.304999 1736.178909 1490.350318 1.011645356 1.177375565 0.987550902 1.384524557 1.185213184 0.757621807 0.940968682 0.689304378 1.164946851 1 10.54143577 -5.250445668 24.95985898 1.056981925 0.810465314 0.502465347 0.139465071 581.6816015 1320632.943 0.020258212 0.051080311 5.62E-06 5.250445668 -0.24651661 (ac)SETAPAAPAAAPPAEKAPVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 SETAPAAPAAAPPAEKAPVKK 21 2 P16403 P16403 HIST1H1C Histone H1.2 0 1 ; SETAPAAPAAAPPAEK(0.003)APVK(0.997)K;SETAPAAPAAAPPAEK(0.04)APVK(0.96)K 81.619 3.29E-05 8338500 4188.9 2290.22 2329.78 3190.5 2404.1 3901.2 2494.76 2051.24 5103.8 3446.3 FALSE TRUE FALSE 3857.344145 2488.176412 2416.123696 3177.298556 2375.432678 3092.047144 2564.756251 2676.653633 4543.925909 3566.058668 1.081682749 0.697738496 0.677533356 0.890983254 0.666122714 0.867076914 0.71921314 0.750591586 1.27421513 1 11.80011472 -7.263168515 24.99558685 1.038572413 0.754950295 0.707226518 0.104117356 50.07946969 723923.9433 0.011966223 0.014061266 5.46E-08 7.263168515 -0.283622118 (ac)SETAPAAPAAAPPAEKAPVK(ac)KK ddPTM_HeLa_Curcumin_4h_R1 1 SETAPAAPAAAPPAEKAPVKKK 22 3 P16403 P16403 HIST1H1C Histone H1.2 0 1 SETAPAAPAAAPPAEK(0.042)APVK(0.78)K(0.178)K 69.081 3.55E-08 3196500 3523 2119.9 2274 3069.1 1981.1 3770.2 1954.4 1877.7 4668.2 3065.9 FALSE TRUE FALSE 3244.150833 2303.13471 2358.27644 3056.400877 1957.476676 2988.218021 2009.235204 2450.202086 4156.110139 3172.439797 1.02260438 0.725982164 0.743363654 0.963422814 0.617025634 0.941930568 0.633340688 0.772339979 1.310067458 1 11.63137707 -7.266599963 24.81497397 1.010674296 0.772742301 0.513001658 0.141988216 201.7738616 970239.7099 0.016169942 0.018786494 5.41E-08 7.266599963 -0.237931995 (ac)SETAPAAPAAPAPAEK(ac)TPVK ddPTM_HeLa_Curcumin_4h_R1 2 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 0 1 ; SETAPAAPAAPAPAEK(1)TPVK;SETAPAAPAAPAPAEK(1)TPVK 52.008 6.05E-06 8708700 6127.1 4691.8 4446.6 5719.6 5712.6 6512.1 5020.6 5042.2 6915.3 4787.2 FALSE TRUE FALSE 5642.13357 5097.338286 4611.394908 5695.933811 5644.480976 5161.417054 5161.464524 6579.543569 6156.708891 4953.554844 1.139006985 1.029026315 0.930926386 1.149867921 1.139480869 1.04196223 1.041971814 1.32824684 1.242886994 1 12.27424851 -4.258587773 24.46821259 1.063218266 1.32824697 0.41584152 0.08655573 118.4915119 1016639.653 0.010176243 0.093995265 5.51E-05 4.258587773 0.265028705 (ac)SETAPAAPAAPAPAEK(ac)TPVKK ddPTM_HeLa_Curcumin_4h_R1 2 SETAPAAPAAPAPAEKTPVKK 21 2 P10412 P10412 HIST1H1E Histone H1.4 0 1 ; SETAPAAPAAPAPAEK(0.977)TPVK(0.023)K;SETAPAAPAAPAPAEK(0.997)TPVK(0.003)K 91.207 1.28E-05 10965500 6101.6 4446 4985.4 5827.4 5695.4 5850.9 5138 5018.2 7133.7 4872.6 FALSE TRUE FALSE 5618.651922 4830.292429 5170.16331 5803.287763 5627.486075 4637.357387 5282.158452 6548.226079 6351.150958 5041.922487 1.114386811 0.95802592 1.025434906 1.151006938 1.116138951 0.919759754 1.047647691 1.298755801 1.259668504 1 12.29975822 -4.261373487 21.44523874 1.048056179 1.298756214 0.33390659 0.095812503 0.464585144 148263.4236 0.010060182 0.077588836 5.48E-05 4.261373487 0.250700035 (ac)SETAPAAPAAPAPAEKT(ph)PVKK ddPTM_HeLa_Curcumin_4h_R1 3 SETAPAAPAAPAPAEKTPVKK 21 2 P10412 P10412 HIST1H1E Histone H1.4 1 0 SETAPAAPAAPAPAEKT(1)PVKK;S(0.003)ET(0.003)APAAPAAPAPAEKT(0.994)PVKK;S(0.005)ET(0.005)APAAPAAPAPAEKT(0.99)PVKK ;; 49.638 0.00064833 309641000 7764 5092.8 6747 7798.4 7423.8 9983.7 7770.2 3472.27 8485 5931.2 TRUE FALSE FALSE 7149.471207 5532.998939 6997.049755 7766.132287 7335.276034 7912.968081 7988.2109 4530.949139 7554.216728 6137.308759 1.164919591 0.901535047 1.140084364 1.265397032 1.195194233 1.289322143 1.301582047 0.738263189 1.230867963 1 12.58339045 -6.534827174 24.96755953 1.064637552 1.178042808 0.043354212 0.1724661 403.5758594 843313.3198 0.025268985 0.035750754 2.92E-07 6.534827174 0.113405256 (ac)SETAPAETAT(ph)PAPVEKS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 1 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 2 0 S(0.043)ET(0.054)APAET(0.432)AT(0.471)PAPVEKS(1)PAK 52.707 0.002042 35730000 3141.9 2253.1 2839.1 3409.3 3510.2 7481.6 8728.6 2587.8 4521.9 2581 TRUE FALSE FALSE 2893.2153 2447.847924 2944.319544 3395.19322 3468.343158 5929.831825 8973.501024 3376.808307 4025.858883 2670.689558 1.083321456 0.916560263 1.10245668 1.271279625 1.298669532 2.220337368 3.35999405 1.264395668 1.507423007 1 11.38299657 -5.296381683 3.174841242 1.056653039 2.417822601 0.504394228 0.500225315 0.113390811 2.314051123 0.061194298 0.157764307 5.05E-06 5.296381683 1.361169561 (ac)SETAPAETATPAPVEKS(ph)PAKK ddPTM_HeLa_Curcumin_4h_R1 2 SETAPAETATPAPVEKSPAKK 21 2 P16401 P16401 HIST1H1B Histone H1.5 1 0 S(0.013)ET(0.002)APAET(0.002)AT(0.001)PAPVEKS(0.983)PAKK;SETAPAETATPAPVEKS(1)PAKK ; 62.1 0.00033171 282863000 6795.6 4182 5359.3 5714.4 5673.1 6851.6 5749.2 3853.6 7199.2 5423.9 TRUE FALSE FALSE 6257.721089 4543.473445 5557.920373 5690.755327 5605.451988 5430.500927 5910.507079 5028.5449 6409.465772 5612.380121 1.114985257 0.809544854 0.990296497 1.0139647 0.998765562 0.967593215 1.053119523 0.895973685 1.142022748 1 12.45439701 (ac)SETAPLAPT(ph)IPAPAEKTPVKK ddPTM_HeLa_Curcumin_4h_R1 1 SETAPLAPTIPAPAEKTPVKK 21 2 P16402 P16402 HIST1H1D Histone H1.3 1 0 S(0.009)ET(0.009)APLAPT(0.943)IPAPAEKT(0.04)PVKK 79.514 2.01E-05 89292000 4000.2 2518.1 3729.4 3325.3 3359.5 5049.3 3712.7 1506.5 4430.6 3292.5 TRUE FALSE FALSE 3683.579949 2735.753344 3867.614845 3311.54079 3319.440157 4002.018263 3816.86837 1965.824915 3944.574265 3406.91413 1.081207159 0.803000381 1.135225221 0.972005945 0.974324574 1.174675413 1.120330077 0.577010409 1.157814408 1 11.73424987 -4.254801484 24.90454554 1.034327422 0.57701019 0.627656438 0.108118464 334.1425564 1253625.621 0.013220494 0.171336869 5.56E-05 4.254801484 -0.457317231 (ac)SETAPLAPTIPAPAEKT(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 1 SETAPLAPTIPAPAEKTPVK 20 1 P16402 P16402 HIST1H1D Histone H1.3 1 0 S(0.003)ET(0.003)APLAPT(0.017)IPAPAEKT(0.976)PVK 58.418 0.00066178 0 1824.6 1520.1 1681 1801.9 2006.3 2545 1927.7 848.39 1964.2 1515.4 TRUE FALSE FALSE 1680.180985 1651.490671 1743.299339 1794.444215 1982.376183 2017.138312 1981.786074 1107.060205 1748.732174 1568.060037 1.071502969 1.053206275 1.11175548 1.144372137 1.264222119 1.286390995 1.263845788 0.706006262 1.115220165 1 10.61476508 -6.750534176 1.583984127 1.032552248 1.155298532 0.026483061 0.158820155 0.626164539 3.191305602 0.026415073 0.038806076 1.78E-07 6.750534176 0.122746285 (ac)SETAPLAPTIPAPAEKT(ph)PVKK ddPTM_HeLa_Curcumin_4h_R1 1 SETAPLAPTIPAPAEKTPVKK 21 2 P16402 P16402 HIST1H1D Histone H1.3 1 0 SETAPLAPT(0.003)IPAPAEKT(0.997)PVKK 64.256 1.52E-05 94195000 4021.7 2482.8 2988.8 3757.6 3226.6 4734.9 3688 1466 3906 2926.2 TRUE FALSE FALSE 3703.378201 2697.402169 3099.567557 3742.052047 3188.124902 3752.828367 3791.475354 1912.976651 3477.521572 3027.885232 1.223090678 0.890853504 1.023674056 1.235863238 1.052921316 1.239422263 1.252185953 0.63178638 1.148498475 1 11.56409481 -4.250558519 24.69968361 1.109052126 0.631786059 0.606043964 0.117502614 786.7657707 1785928.056 0.017562088 0.345412503 5.62E-05 4.250558519 -0.477266067 (ac)SGEDEQQEQTIAEDLVVTK ddPTM_HeLa_Curcumin_4h_R1 2 SGEDEQQEQTIAEDLVVTK 19 0 Q9UQ80;F8VR77 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 0 ; ; 180.61 1.46E-133 18421700 9386.7 8250 8984 8852.3 9143.6 11094.2 8527.5 9477.8 10174.5 9062.5 FALSE FALSE TRUE 8643.73279 8963.093239 9316.954943 8815.671528 9034.568542 8793.137863 8766.758699 12367.53759 9058.382805 9377.4212 0.921760109 0.955816428 0.993551931 0.940095506 0.963438492 0.937692536 0.934879485 1.318863398 0.965978024 1 13.19497552 -4.25907475 24.99918427 0.959311664 1.318863523 0.953491724 0.023969412 41.16042197 435125.9291 0.004364299 0.039227864 5.51E-05 4.25907475 0.359551859 (ac)SGGSSCSQTPSR ddPTM_HeLa_Curcumin_4h_R1 1 SGGSSCSQTPSR 12 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 0 0 51.436 0.0012807 144120 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 (ac)SGYSS(ph)DRDR ddPTM_HeLa_Curcumin_4h_R1 1 SGYSSDRDR 9 1 P17844-2;P17844;J3QRQ7;J3QR02;J3KRX8;X6RLV5;J3QKN9;J3QS79 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 1 0 SGYS(0.104)S(0.896)DRDR 63.426 0.012098 624180000 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)SGYSSDRDR ddPTM_HeLa_Curcumin_4h_R1 1 SGYSSDRDR 9 1 P17844-2;P17844;J3QRQ7;J3QR02;J3KRX8;X6RLV5;J3QKN9;J3QS79 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 0 60.76 0.0063455 437380 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 (ac)SHTILLVQPTK ddPTM_HeLa_Curcumin_4h_R1 2 SHTILLVQPTK 11 0 P84090;G3V279 P84090 ERH Enhancer of rudimentary homolog 0 0 ; ; 70.977 7.34E-13 12045800 14641.3 11681 13338.2 14437.9 14964.6 17379.8 15066.9 14448 14494.5 13507.1 FALSE FALSE TRUE 13482.42566 12690.65359 13832.52543 14378.1598 14786.15692 13775.03357 15489.63666 18853.12869 12904.48961 13976.47072 0.964651658 0.908001301 0.989700884 1.02874038 1.057932093 0.985587409 1.108265239 1.348919128 0.923301016 1 13.77071248 -1.00000003 0.834599376 0.981299498 119.877488 0.881818003 0.041199969 132.5949652 0.373013514 0.006155892 29913.98104 0.099999993 1.00000003 118.8961885 (ac)SIFT(ph)PTNQIR ddPTM_HeLa_Curcumin_4h_R1 1 SIFTPTNQIR 10 0 Q9Y3A5;A0A087X020;F8WE72 Q9Y3A5 SBDS Ribosome maturation protein SBDS 1 0 S(0.004)IFT(0.982)PT(0.013)NQIR 84.507 0.019153 4385200 214.55 228.62 293.38 213.63 244.9 274.99 316.09 304.2 280.87 160.67 TRUE FALSE FALSE 197.5681411 248.3808941 304.2529209 212.7460557 241.9797274 217.9539742 324.9586347 396.9491796 250.0592637 166.2532705 1.188356418 1.493991025 1.830056756 1.279650349 1.455488525 1.310975559 1.954599952 2.387617268 1.504086283 1 7.377238911 -1 0.242883029 1.026741213 8.282835634 0.50832532 0.273422508 20.50355973 0.253815285 0.14640147 60.89445865 0.1 1 7.256094421 (ac)SILK(ac)IHAR ddPTM_HeLa_Curcumin_4h_R1 1 SILKIHAR 8 1 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798 P06733 ENO1 Alpha-enolase;Enolase 0 1 SILK(1)IHAR 54.549 0.0004529 4085900 543.45 471.73 608.11 647.42 409.9 469.09 449.46 405.47 475.38 537.36 FALSE TRUE FALSE 500.4353591 512.5042392 630.6470915 644.7411476 405.0122102 371.7954463 462.0706379 529.0959364 423.2320033 556.03322 0.900009821 0.921715144 1.134189593 1.1595371 0.728395707 0.668656895 0.831012647 0.951554543 0.761163161 1 9.119027269 -5.734599295 24.99969506 0.97713353 0.78846631 0.336857094 0.126686178 181.829937 169361.1668 0.016916437 0.033825531 1.84E-06 5.734599295 -0.18866722 (ac)SK(ac)SESPKEPEQLR ddPTM_HeLa_Curcumin_4h_R1 2 SKSESPKEPEQLR 13 2 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 0 1 ; SK(1)SESPKEPEQLR;SK(1)SESPKEPEQLR 104.82 4.53E-15 32335000 3744.5 4073.9 3707.8 3554.8 3434.4 4979.3 2626.2 2376.6 3818.1 3772.5 FALSE TRUE FALSE 3448.118874 4426.029763 3845.21433 3540.091179 3393.447023 3946.537052 2699.884104 3101.214399 3399.263982 3903.594094 0.883319011 1.133834527 0.985044612 0.90687994 0.869313494 1.011000877 0.691640585 0.794451043 0.870803649 1 11.93058733 -4.760784485 24.99979981 0.955589917 0.743045773 0.530184992 0.080743094 9.533626317 363850.4134 0.011193659 0.037435593 1.73E-05 4.760784485 -0.212544144 (ac)SKS(ph)ESPKEPEQLRK ddPTM_HeLa_Curcumin_4h_R1 1 SKSESPKEPEQLRK 14 3 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 1 0 S(0.329)KS(0.448)ES(0.223)PKEPEQLRK 99.161 0.0015974 8427600 2728 2238.8 2081.1 2786.2 1380.3 3110.8 2139.5 3110.7 4414.7 3721.2 TRUE FALSE FALSE 2512.075921 2432.311896 2158.227397 2774.671443 1363.840824 2465.585014 2199.528612 4059.13811 3930.418455 3850.511423 0.652400589 0.631685412 0.560504089 0.720598159 0.354197319 0.640326633 0.571230252 1.054181553 1.020752317 1 11.91083436 -9.001611729 0.700849388 1.014060929 0.631229032 0.426898281 0.165966163 0.581967668 0.500910686 0.125603391 0.034228775 9.96E-10 9.001611729 -0.382831897 (ac)SKSES(ph)PKEPEQLR ddPTM_HeLa_Curcumin_4h_R1 1 SKSESPKEPEQLR 13 2 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 1 0 S(0.302)KS(0.302)ES(0.396)PKEPEQLR 50.534 0.0040044 680620000 8374.1 6468.2 5271.7 6691.4 4806.9 8052 6898.3 9139.4 12088 9976.5 TRUE FALSE FALSE 7711.281149 7027.282386 5467.073839 6663.71276 4749.580857 6381.924435 7091.847732 11925.96099 10761.97664 10323.18263 0.746986799 0.680728283 0.529591894 0.645509529 0.460088814 0.618212877 0.686982686 1.155260099 1.042505691 1 13.3336002 -8.515266996 0.758826793 0.983031117 0.668121389 0.349783693 0.176950469 0.530508923 0.630270149 0.08284175 0.039613425 3.05E-09 8.515266996 -0.314909728 (ac)SLLDGLASS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 SLLDGLASSPR 11 0 E9PI10;E9PK87;F8W6N5;Q3YBR2 E9PI10 TBRG1 Transforming growth factor beta regulator 1 1 0 SLLDGLAS(0.102)S(0.898)PR;SLLDGLAS(0.266)S(0.734)PR ; 143.31 4.23E-05 8531300 148.64 117.1 220.43 152.02 209.814 140.76 198.5 131.71 185.1 120.97 TRUE FALSE FALSE 136.8749872 127.2216022 228.5993297 151.3909815 207.3121051 111.5647893 204.0693758 171.8677727 164.7949931 125.1736985 1.09348041 1.016360495 1.826256893 1.209447219 1.656195411 0.891279803 1.630289575 1.37303423 1.31653051 1 6.967787645 -6.86688569 21.4023019 1.043270699 1.4163872 0.259515165 0.259135857 2.848770111 567.3416487 0.035515446 0.046676495 1.36E-07 6.86688569 0.373116501 (ac)SQPGQK(ac)PAASPRPR ddPTM_HeLa_Curcumin_4h_R1 1 SQPGQKPAASPRPR 14 2 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;F8W7E0;E9PSG1 P20810-6 CAST Calpastatin 0 1 SQPGQK(1)PAASPRPR 80.706 0.00018032 1165600 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)SQPGQKPAAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 SQPGQKPAASPR 12 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;F8W7E0;E9PSG1 P20810-6 CAST Calpastatin 1 0 SQPGQKPAAS(1)PR;SQPGQKPAAS(1)PR;SQPGQKPAAS(1)PR ;; 106.79 0.00061813 351832000 8454.5 7068 7248.1 7716.5 7439.5 7968 6732.7 7414.3 7552.9 5734.4 TRUE FALSE FALSE 7785.317404 7678.926426 7516.720962 7684.571168 7350.788821 6315.346982 6921.601442 9674.885939 6724.365766 5933.669973 1.312057704 1.294127658 1.266791209 1.295078965 1.238826705 1.064323936 1.166495857 1.630506244 1.133255775 1 12.53470897 -9.27051535 0.871654055 0.990155679 1.273192442 0.2503297 0.142173469 0.56664188 0.730482471 0.107482408 0.025550703 5.36E-10 9.27051535 0.283036763 (ac)SQPGQKPAAS(ph)PRPR ddPTM_HeLa_Curcumin_4h_R1 1 SQPGQKPAASPRPR 14 2 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;F8W7E0;E9PSG1 P20810-6 CAST Calpastatin 1 0 SQPGQKPAAS(1)PRPR 57.499 0.01005 542620000 6099.8 4851.2 5276.3 6099.9 5439.3 6655.2 5241 5332.6 6406.1 4689.7 TRUE FALSE FALSE 5616.994394 5270.516111 5471.84432 6074.66023 5374.4399 5274.8365 5388.048355 6958.485192 5703.366857 4852.666726 1.15750673 1.086107167 1.127595326 1.251818963 1.107522977 1.08699748 1.110327302 1.433950771 1.175305699 1 12.24456207 -13.52287632 0.030445909 1.59E-09 1.848296659 0.153619684 0.10326272 937.0221948 2.290332307 106.2623251 45.03353101 3.00E-14 13.52287632 1.848296658 (ac)SQPGQKPAASPRPR ddPTM_HeLa_Curcumin_4h_R1 1 SQPGQKPAASPRPR 14 2 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;F8W7E0;E9PSG1 P20810-6 CAST Calpastatin 0 0 43.297 0.012365 1746300 2067.2 1566.8 1787.3 1838.6 2012.6 2610.1 1811.2 1592.3 2103.1 1806.2 FALSE FALSE TRUE 1903.578939 1702.22721 1853.53891 1830.99236 1988.601059 2068.735838 1862.017397 2077.78494 1872.395192 1868.965316 1.018520206 0.910785875 0.991746018 0.979682365 1.064011752 1.106888299 0.996282479 1.111730069 1.001835174 1 10.86802408 -5.750237426 24.14565966 0.997552884 1.067136364 0.494392152 0.041163571 112.2183536 241882.2624 0.005921683 0.011749488 1.78E-06 5.750237426 0.06958348 (ac)SRHEGVS(ph)CDACLK ddPTM_HeLa_Curcumin_4h_R1 1 SRHEGVSCDACLK 13 1 Q9P0J7 Q9P0J7 KCMF1 E3 ubiquitin-protein ligase KCMF1 1 0 S(0.345)RHEGVS(0.655)CDACLK 53.252 0.0063492 15931000 4141.6 3763.5 3035.9 3602.3 4033.6 5679 3949.6 3961.5 4523.1 4043.1 TRUE FALSE FALSE 3813.78799 4088.80017 3148.413125 3587.394637 3985.501954 4501.111384 4060.415146 5169.343113 4026.927246 4183.597424 0.911604919 0.977340732 0.752561206 0.857490402 0.95264949 1.07589496 0.970555896 1.235621545 0.962551326 1 12.03052832 (ac)SS(ph)ILPFTPPIVKR ddPTM_HeLa_Curcumin_4h_R1 1 SSILPFTPPIVKR 13 1 P84022 P84022 SMAD3 Mothers against decapentaplegic homolog 3 1 0 S(0.379)S(0.598)ILPFT(0.023)PPIVKR 52.278 0.018019 15514000 1060 703.02 602.11 808.78 465.82 973.42 709.01 383.18 1114.2 927.05 TRUE FALSE FALSE 976.0998815 763.7859162 624.4247263 805.4334827 460.2654007 771.5217193 728.9029124 500.0098181 991.9750476 959.2649185 1.017549858 0.796220003 0.650940855 0.839636129 0.479810521 0.804284306 0.759855696 0.521242681 1.034099161 1 9.905785487 -7.107305911 2.933250306 1.00904981 0.684472905 0.666623199 0.107534158 0.108601115 1.797285527 0.016873388 0.021103828 7.81E-08 7.107305911 -0.324576905 (ac)SS(ph)PASTPSRR ddPTM_HeLa_Curcumin_4h_R1 1 SSPASTPSRR 10 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53;A0A3B3IS88 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 0 S(0.179)S(0.818)PAS(0.002)TPSRR 100.02 0.0070057 140760000 0 0 0 0 0 52.843 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 41.88276614 0 0 0 0 0 (ac)SSDASQGVITT(ph)PPPPSMPHK ddPTM_HeLa_Curcumin_4h_R1 1 SSDASQGVITTPPPPSMPHK 20 0 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 0 S(0.175)S(0.175)DAS(0.175)QGVIT(0.052)T(0.424)PPPPSMPHK 49.773 0.0028458 18885000 1389.2 1382.8 1301.2 1139.1 1487.4 1637.2 1454.9 1352.8 1572 1352.9 TRUE FALSE FALSE 1279.243354 1502.32307 1349.423617 1134.386706 1469.663726 1297.626265 1495.720578 1765.262492 1399.555533 1399.913174 0.913801925 1.073154463 0.963933793 0.810326474 1.049824913 0.92693339 1.068438104 1.260979984 0.999744526 1 10.45112164 -4.348986858 2.328020118 0.960864937 1.304194497 0.612835838 0.071005516 0.22455747 1.640460441 0.009653101 0.143606656 4.48E-05 4.348986858 0.343329561 (ac)SSIGTGYDLSASTFS(ph)PDGR ddPTM_HeLa_Curcumin_4h_R1 3 SSIGTGYDLSASTFSPDGR 19 0 P25788-2;P25788;G3V3W4;G3V5N4 P25788-2 PSMA3 Proteasome subunit alpha type-3 1 0 SSIGTGYDLS(0.008)AS(0.079)T(0.079)FS(0.834)PDGR;SSIGTGYDLSAS(0.001)T(0.041)FS(0.958)PDGR;SSIGTGYDLSAS(0.021)T(0.064)FS(0.915)PDGR ;; 122.22 1.03E-10 0 1071.43 928.89 919.93 1089.73 888.6 1352.32 1087.28 983.04 1295.28 1083.34 TRUE FALSE FALSE 986.6251849 1009.179113 954.0234151 1085.220986 878.0040254 1071.833588 1117.786151 1282.764371 1153.191025 1120.985984 0.880140518 0.900260241 0.851057398 0.968095053 0.783242643 0.956152533 0.997145518 1.144317938 1.028729209 1 10.13055252 -4.334072032 2.031373073 0.923560109 1.186716075 0.499767219 0.068568645 0.402205615 2.003975751 0.009817304 0.183999373 4.63E-05 4.334072032 0.263155966 (ac)SSNSASAANGNDSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 SSNSASAANGNDSKK 15 1 A6NLN1;K7ES59 A6NLN1 PTBP1 0 1 SSNSASAANGNDSK(1)K 107.97 5.50E-13 400640 224.79 242.02 174.04 205.06 349.63 460.12 286.2 319.39 331.78 305.67 FALSE TRUE FALSE 206.9976343 262.9391304 180.4900755 204.2115161 345.4608906 364.6859254 294.2300017 416.7705407 295.3845641 316.2920097 0.654451039 0.83131765 0.570643804 0.645642349 1.092221365 1.153003915 0.930247975 1.317676476 0.933898281 1 8.3051133 -5.696726045 8.829255781 0.798534268 1.113020274 0.554789615 0.152737809 0.230739676 28.90937749 0.025979751 0.051980345 2.01E-06 5.696726045 0.314486006 (ac)SSPAST(ph)PSRR ddPTM_HeLa_Curcumin_4h_R1 1 SSPASTPSRR 10 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;E5RFR3;E5RG53;A0A3B3IS88 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 0 SSPAS(0.15)T(0.654)PS(0.196)RR 69.864 0.0034648 101100000 0 0 63.85 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 66.21633717 0 0 0 0 0 0 0 0 (ac)STEAQRVDDSPSTS(ph)GGSSDGDQR ddPTM_HeLa_Curcumin_4h_R1 1 STEAQRVDDSPSTSGGSSDGDQR 23 1 F8WF15;F8W8F0;C9J180;Q96LR5 F8WF15 UBE2E2 Ubiquitin-conjugating enzyme E2 E2 1 0 S(0.004)T(0.004)EAQRVDDS(0.256)PS(0.11)T(0.043)S(0.441)GGS(0.104)S(0.037)DGDQR 69.07 3.55E-24 0 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)STGPTAAT(ph)GSNRR ddPTM_HeLa_Curcumin_4h_R1 1 STGPTAATGSNRR 13 1 Q15836 Q15836 VAMP3 Vesicle-associated membrane protein 3 1 0 STGPTAAT(0.5)GS(0.5)NRR 78.529 0.0089891 5088500 484.26 519.45 311.21 533.97 233.52 434.01 389.16 310.98 475.32 963.57 TRUE FALSE FALSE 445.93031 564.3489434 322.7437164 531.7605736 230.7354265 343.9914337 400.0787822 405.7963704 423.1785852 997.0539858 0.447247909 0.566016436 0.323697333 0.533331777 0.231417185 0.345007832 0.401260903 0.406995385 0.424428959 1 9.961527812 -9.438158676 0.386219287 1.242099914 0.35576639 0.000542076 0.199777246 0.630779249 0.111433498 0.235890339 0.028881758 3.65E-10 9.438158676 -0.886333525 (ac)STGPTAATGS(ph)NRR ddPTM_HeLa_Curcumin_4h_R1 1 STGPTAATGSNRR 13 1 Q15836 Q15836 VAMP3 Vesicle-associated membrane protein 3 1 0 STGPTAAT(0.172)GS(0.828)NRR 84.734 0.0056943 6120500 122.6 178.5 59.604 246.03 0 106.92 151.26 0 55.245 236.27 TRUE FALSE FALSE 112.8960806 193.9287446 61.81297667 245.011993 0 84.74358676 155.5039485 0 49.18476172 244.4803649 0.461779745 0.793228302 0.252834115 1.002174523 0 0.346627374 0.636059049 0 0.201180826 1 7.933574792 -13.52287874 0.123680552 2.933675346 0.142816514 0 0.375141277 64.10036912 0.56882725 30.88241635 1.145285693 3.00E-14 13.52287874 -2.790858831 (ac)STNENANT(ph)PAAR ddPTM_HeLa_Curcumin_4h_R1 3 STNENANTPAAR 12 0 P52292;J3QLL0;J3KS65;J3QL07 P52292 KPNA2 Importin subunit alpha-1 1 0 STNENANT(1)PAAR;STNENANT(1)PAAR;STNENANT(1)PAAR ;; 183.06 2.56E-26 38650900 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 (ac)STNENANTPAAR ddPTM_HeLa_Curcumin_4h_R1 1 STNENANTPAAR 12 0 P52292;J3QLL0;J3KS65;J3QL07 P52292 KPNA2 Importin subunit alpha-1 0 0 45.598 0.0010831 464810 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 (ac)STVHEILCK ddPTM_HeLa_Curcumin_4h_R1 2 STVHEILCK 9 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YNP5;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4 P07355 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 0 ; ; 61.999 4.50E-06 23436000 12007.6 9660.5 8910 9872.5 17085.2 29597 15116.4 12833.8 18647.5 9408 FALSE FALSE TRUE 11057.18579 10495.51057 9240.212438 9831.650211 16881.47015 23458.24857 15540.5255 16746.76654 16601.9159 9734.9273 1.135826232 1.078129322 0.949181453 1.009935658 1.734113633 2.40969941 1.596367905 1.720276487 1.705397009 1 13.24895449 -5.698213368 4.746567553 1.053323038 1.903604831 0.588820868 0.289821379 0.065509516 2.905651844 0.029018357 0.058550181 2.00E-06 5.698213368 0.850281793 (ac)SVPAFIDIS(ph)EEDQAAELR ddPTM_HeLa_Curcumin_4h_R1 2 SVPAFIDISEEDQAAELR 18 0 E9PRI2;E7ESM3;Q7L2H7 E9PRI2 EIF3M Eukaryotic translation initiation factor 3 subunit M 1 0 S(0.012)VPAFIDIS(0.988)EEDQAAELR;S(0.001)VPAFIDIS(0.999)EEDQAAELR ; 108.49 0.0002283 3076100 65.201 64.608 0 0 0 0 128.82 0 0 0 TRUE FALSE FALSE 60.04027205 70.19242763 0 0 0 0 132.4343425 0 0 0 0 (ac)SVPAFIDISEEDQAAELR ddPTM_HeLa_Curcumin_4h_R1 2 SVPAFIDISEEDQAAELR 18 0 E9PRI2;E7ESM3;Q7L2H7 E9PRI2 EIF3M Eukaryotic translation initiation factor 3 subunit M 0 0 ; ; 170.95 3.97E-23 6444200 132.17 0 50.036 148.08 64.607 113.15 171.431 0 282.348 0 FALSE FALSE TRUE 121.708605 0 51.89037818 147.4672842 63.83660372 89.68141454 176.2408925 0 251.3751308 0 0 (ac)SY(ph)GRPPPDVEGMTSLK ddPTM_HeLa_Curcumin_4h_R1 1 SYGRPPPDVEGMTSLK 16 1 J3KP15;Q01130;J3QL05;Q01130-2 J3KP15 SRSF2 Serine/arginine-rich splicing factor 2 1 0 S(0.279)Y(0.721)GRPPPDVEGMTSLK 100.19 0.0010183 24263000 2112.4 1680.5 1997.1 2215.8 1602.4 2854.7 3606.4 1797.9 1994.1 1889.1 TRUE FALSE FALSE 1945.201311 1825.754932 2071.114283 2206.631607 1583.292427 2262.603041 3707.585878 2346.071433 1775.352219 1954.746084 0.995117129 0.9340113 1.059531107 1.128858436 0.809973448 1.157492044 1.89670971 1.20019242 0.908226512 1 10.9327655 -4.955973071 8.725494321 0.996249091 1.545902134 0.620879318 0.176230911 0.114935163 20.75725695 0.020414003 0.061398583 1.11E-05 4.955973071 0.549653043 (ac)TECFLPPTSS(ph)PSEHR ddPTM_HeLa_Curcumin_4h_R1 1 TECFLPPTSSPSEHR 15 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 0 TECFLPPT(0.161)S(0.161)S(0.517)PS(0.161)EHR 71.031 0.006284 9966700 352.74 273.43 226.6 301.06 232.11 266.71 283.75 442.14 288.95 437.2 TRUE FALSE FALSE 324.8202568 297.0640708 234.9979953 299.8142935 229.3422398 211.3913396 291.7112613 576.9464506 257.2529079 452.3926675 0.718005132 0.656650941 0.519455801 0.662730223 0.506953928 0.467274018 0.644818721 1.275322286 0.568649597 1 8.821431736 -8.683174643 0.743640886 0.990417483 0.657331693 0 0.251093758 0.669675236 0.733811675 0.116522321 0.046989199 2.07E-09 8.683174643 -0.333085789 (ac)TECFLPPTSS(ph)PSEHRR ddPTM_HeLa_Curcumin_4h_R1 2 TECFLPPTSSPSEHRR 16 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 0 TECFLPPT(0.051)S(0.09)S(0.59)PS(0.269)EHRR;TECFLPPT(0.031)S(0.164)S(0.791)PS(0.015)EHRR ; 66.12 0.0061293 15594400 1476.94 1035.03 1123.89 1247.39 1482.14 1428.18 1483.17 766.44 1324.27 1280.85 TRUE FALSE FALSE 1360.038641 1124.493381 1165.542352 1242.228631 1464.466449 1131.959369 1524.783758 1000.124028 1179.000894 1325.359442 1.026165882 0.848444087 0.87941604 0.93727678 1.104957947 0.854077266 1.150468099 0.75460588 0.889570675 1 10.37216796 (ac)TEVMMNTQPMEEIGLS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 12 TEVMMNTQPMEEIGLSPR 18 0 B5MBX5 B5MBX5 LBH 1 0 TEVMMNTQPMEEIGLS(1)PR;TEVMMNTQPMEEIGLS(1)PR;TEVMMNTQPMEEIGLS(1)PR;TEVMMNTQPMEEIGLS(1)PR;TEVMMNTQPMEEIGLS(1)PR;TEVMMNTQPMEEIGLS(1)PR;TEVMMNT(0.001)QPMEEIGLS(0.999)PR;TEVMMNTQPMEEIGLS(1)PR;TEVMMNTQPMEEIGLS(1)PR;TEVMMNTQPMEEIGLS(1)PR;TEVMMNTQPMEEIGLS(1)PR;TEVMMNTQPMEEIGLS(1)PR ;;;;;;;;;;; 274.08 1.35E-152 83215000 2292.935 2436.68 2259.034 2491.669 2477.1 2554.62 2077.522 1992.07 2392.209 2059.521 TRUE FALSE FALSE 2111.446775 2647.295762 2342.755787 2481.359134 2447.5622 2024.763015 2135.811676 2599.442973 2129.789658 2131.089201 0.990782917 1.242226632 1.099323194 1.164361929 1.148502934 0.950107116 1.002215991 1.219772017 0.999390197 1 11.05737527 (ac)TEWETAAPAVAET(ph)PDIK ddPTM_HeLa_Curcumin_4h_R1 1 TEWETAAPAVAETPDIK 17 0 M0R0F0;M0R0R2;P46782;M0QZN2 M0R0F0 RPS5 "40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed" 1 0 TEWET(0.001)AAPAVAET(0.999)PDIK 84.653 0.00058395 0 1048.5 1015.9 1058.9 1254 1356.1 1481 1210.5 1544.7 1082.4 1437.1 TRUE FALSE FALSE 965.5101186 1103.709869 1098.143766 1248.81128 1339.929393 1173.823906 1244.463372 2015.671919 963.663428 1487.039118 0.649283605 0.742219795 0.738476717 0.839797195 0.901072054 0.78936989 0.836873326 1.355493541 0.648041747 1 10.53822688 -4.261709436 5.84166342 0.820135123 1.371324041 0.713166157 0.105727378 0.073434532 11.18516685 0.018469316 0.160317731 5.47E-05 4.261709436 0.551188918 (ac)TTSS(ph)IRR ddPTM_HeLa_Curcumin_4h_R1 1 TTSSIRR 7 1 J3KSR0;J3QKL8;J3KSF8;J3KTF6;J3KSA6;J3KSC7;J3QLN2;F6PQP6;E9PBC1;I3L2B2;O95208-2;O95208 J3KSR0 EPN2 Epsin-2 1 0 TT(0.015)S(0.034)S(0.951)IRR 56.81 0.008558 0 425.72 904.33 595.91 341.58 203.22 601.68 382.48 366.44 502.15 685.23 TRUE FALSE FALSE 392.0238128 982.4962556 617.9949488 340.1666325 200.7967342 476.8847857 393.2113594 478.1658691 447.0654013 709.0416915 0.552892471 1.385667821 0.871591835 0.479755474 0.283194538 0.672576509 0.554567332 0.674383291 0.630520612 1 9.46972665 -6.263682413 24.63444757 0.843397988 0.527987205 0.355176988 0.235452763 176.4794241 1938213.99 0.039980062 0.06294176 5.45E-07 6.263682413 -0.315410784 (ac)VDYSVWDHIEVS(ph)DDEDETHPNIDTASLFR ddPTM_HeLa_Curcumin_4h_R1 1 VDYSVWDHIEVSDDEDETHPNIDTASLFR 29 0 K7EQA9;Q16543;K7EJ06;K7EKQ2 K7EQA9 CDC37 "Hsp90 co-chaperone Cdc37;Hsp90 co-chaperone Cdc37, N-terminally processed" 1 0 VDY(0.151)S(0.164)VWDHIEVS(0.682)DDEDET(0.002)HPNIDTASLFR 56.332 2.69E-06 4582900 0 0 0 0 0 122.05 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 96.73545421 0 0 0 0 0 (ac)VSVINTVDTSHEDMIHDAQMDYYGTR ddPTM_HeLa_Curcumin_4h_R1 1 VSVINTVDTSHEDMIHDAQMDYYGTR 26 0 P55735 P55735 SEC13 Protein SEC13 homolog 0 0 105.51 1.49E-08 8085900 393.65 680.8 305.3 382.86 141.83 1099.7 578.04 368.87 710.27 580.32 FALSE FALSE TRUE 362.4921871 739.6453184 316.6146866 381.2758268 140.1387699 871.6098238 594.2582467 481.3367649 632.355158 600.4860768 0.6036646 1.231744327 0.527263993 0.634945324 0.233375552 1.451507133 0.989628685 0.80157856 1.05307214 1 9.229986985 -5.24093562 24.98939167 0.771959655 1.071777068 0.186544957 0.310390768 1167.818852 1423301.82 0.043200803 0.110004638 5.74E-06 5.24093562 0.299817413 AAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLS(ph)GPAEVGPGAVGERTPR ddPTM_HeLa_Curcumin_4h_R1 1 AAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTPR 55 1 R4GMQ1;O60341;O60341-2 R4GMQ1 KDM1A Lysine-specific histone demethylase 1A 1 0 AAAAAAAAAAAAT(0.001)GT(0.001)EAGPGT(0.007)AGGS(0.029)ENGS(0.029)EVAAQPAGLS(0.467)GPAEVGPGAVGERT(0.467)PR 69.032 2.42E-10 12269000 1670.9 1683.4 1341 1409.3 1618.8 2489.7 1899.4 1311.5 1836.1 1516.8 TRUE FALSE FALSE 1538.646502 1828.905595 1390.69864 1403.46869 1599.496867 1973.308155 1952.692052 1711.370313 1634.684424 1569.508687 0.980336404 1.165272681 0.886072598 0.894208934 1.019106731 1.257277625 1.244142239 1.090386008 1.041526203 1 10.6160973 -5.339082023 5.779053706 0.989341441 1.20137293 0.538515191 0.084434262 0.115013975 6.599356589 0.011504937 0.026160906 4.58E-06 5.339082023 0.212031489 AAAAAAALQAK ddPTM_HeLa_Curcumin_4h_R1 2 AAAAAAALQAK 11 0 P36578;H3BM89;H3BU31 P36578 RPL4 60S ribosomal protein L4 0 0 ; ; 214.32 2.22E-30 8448000 9933.6 7076.9 8850.9 7975.2 9318.7 10503.1 8087.9 7953 8271.7 8828.7 FALSE FALSE TRUE 9147.345078 7688.595702 9178.92214 7942.200736 9207.580589 8324.638666 8314.824707 10377.83309 7364.315205 9135.496668 1.001296964 0.841617701 1.004753488 0.8693781 1.007890531 0.91124095 0.910166684 1.135990025 0.806120945 1 13.15726745 AAAAAAGSGT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 AAAAAAGSGTPR 12 0 Q9NR33 Q9NR33 POLE4 DNA polymerase epsilon subunit 4 1 0 AAAAAAGS(0.105)GT(0.895)PR;AAAAAAGS(0.004)GT(0.996)PR ; 114.76 0.012069 85545000 5012.1 7082.3 6670.6 5875.9 5252.1 5189.3 4855.9 2117.4 5944.3 6260.3 TRUE FALSE FALSE 4615.386996 7694.462454 6917.818304 5851.587083 5189.472138 4112.980685 4992.143485 2762.985513 5292.225162 6477.844959 0.71248803 1.187812074 1.067919709 0.903323114 0.80111089 0.634930399 0.770648806 0.426528503 0.816973113 1 12.66129822 -4.203377532 0.774443739 0.904005275 0.181767784 0.532837534 0.14305125 2.130989925 0.855641303 0.027526442 1.354773647 6.26E-05 4.203377532 -0.722237491 AAAAAATAPPS(ph)PGPAQPGPR ddPTM_HeLa_Curcumin_4h_R1 3 AAAAAATAPPSPGPAQPGPR 20 0 Q6SPF0 Q6SPF0 SAMD1 Atherin 1 0 AAAAAATAPPS(1)PGPAQPGPR;AAAAAAT(0.002)APPS(0.998)PGPAQPGPR;AAAAAAT(0.046)APPS(0.954)PGPAQPGPR ;; 287 3.73E-83 150844000 11915.2 9964.1 9624.1 10190.2 9875.8 12096.4 10922.1 6094.9 11812.8 10258.5 TRUE FALSE FALSE 10972.09935 10825.3524 9980.777612 10148.03565 9758.037535 9587.470285 11228.54473 7953.206953 10516.96539 10614.98211 1.033642754 1.019818243 0.940253833 0.956010622 0.919270276 0.903201737 1.057801569 0.749243557 0.990766191 1 13.37381432 -6.696698883 3.717244404 1.016830664 0.92609246 0.273100923 0.07170442 0.214890202 5.973254869 0.010299898 0.014594431 2.01E-07 6.696698883 -0.090738204 AAAAAWEEPSS(ph)GNGTAR ddPTM_HeLa_Curcumin_4h_R1 1 AAAAAWEEPSSGNGTAR 17 0 Q9P258 Q9P258 RCC2 Protein RCC2 1 0 AAAAAWEEPS(0.005)S(0.995)GNGTAR 212.03 1.27E-11 13839000 1792.9 1488.7 1344.1 1528 1493.3 2543.3 2208.3 1431.3 1928.6 1580.3 TRUE FALSE FALSE 1650.990073 1617.376594 1393.913528 1521.677541 1475.493373 2015.790911 2270.258955 1867.696781 1717.037405 1635.215307 1.009646904 0.989090909 0.852434246 0.930567084 0.902323606 1.232737305 1.388354759 1.142171782 1.050037507 1 10.67526489 -5.18341408 5.761970943 0.980327912 1.27337128 0.739482861 0.078959245 0.084614197 4.820939809 0.010816865 0.028068391 6.56E-06 5.18341408 0.293043368 AAAAAWEEPSSGNGTAR ddPTM_HeLa_Curcumin_4h_R1 1 AAAAAWEEPSSGNGTAR 17 0 Q9P258 Q9P258 RCC2 Protein RCC2 0 0 150.14 0.0033195 1200900 449.65 317.42 323 328.41 294.22 352.05 353.89 362.24 366.22 217.24 FALSE FALSE TRUE 414.059728 344.8563704 334.9706641 327.0511264 290.7116187 279.0308616 363.819201 472.6853085 326.0465822 224.7890738 1.841992233 1.534133152 1.490155453 1.45492448 1.293264008 1.24130082 1.618491481 2.102794857 1.45045565 1 7.812428103 -9.505912061 1.250521847 0.999488467 1.578729222 0.13279728 0.273044453 0.365836094 1.02251012 0.180658884 0.043532053 3.12E-10 9.505912061 0.579240755 AAAAGLGHPAS(ph)PGGS(ph)EDGPPGSEEEDAAR ddPTM_HeLa_Curcumin_4h_R1 1 AAAAGLGHPASPGGSEDGPPGSEEEDAAR 29 0 Q99856 Q99856 ARID3A AT-rich interactive domain-containing protein 3A 2 0 AAAAGLGHPAS(0.995)PGGS(0.508)EDGPPGS(0.497)EEEDAAR 60.675 0.0044013 4736100 919.63 998.96 1028 1218.4 1404.3 1347.8 1110.2 1055.6 1243.6 1067.6 TRUE FALSE FALSE 846.8403151 1085.305651 1066.098584 1213.358584 1387.55464 1068.251087 1141.349224 1377.447581 1107.180191 1104.699021 0.766580127 0.982444658 0.965057961 1.098361238 1.256047678 0.967006458 1.033176642 1.246898526 1.002246015 1 10.10943764 -6.492307418 2.024542577 0.892327239 1.114911607 0.389809227 0.106046752 0.236762667 1.932253286 0.019444935 0.030901627 3.22E-07 6.492307418 0.222584368 AAAAGLGHPAS(ph)PGGSEDGPPGSEEEDAAR ddPTM_HeLa_Curcumin_4h_R1 2 AAAAGLGHPASPGGSEDGPPGSEEEDAAR 29 0 Q99856 Q99856 ARID3A AT-rich interactive domain-containing protein 3A 1 0 AAAAGLGHPAS(0.963)PGGS(0.037)EDGPPGSEEEDAAR;AAAAGLGHPAS(1)PGGSEDGPPGSEEEDAAR ; 168.54 2.67E-16 17645600 3762.7 3127.61 3011.24 3631.3 3354.5 3669 3272.9 2792.66 3448.8 2836.3 TRUE FALSE FALSE 3464.878325 3397.946672 3122.839203 3616.274643 3314.499778 2908.008042 3364.728765 3644.129178 3070.475268 2934.861214 1.180593586 1.157787856 1.064050044 1.232179098 1.129354861 0.990850275 1.146469465 1.241670019 1.046207996 1 11.51907657 -9.379182467 1.041782772 0.997951671 1.141433403 0.305265182 0.071175375 0.480171888 0.911149181 0.051764445 0.012585441 4.18E-10 9.379182467 0.143481732 AAAASAAEAGIATTGTEGERDS(ph)DDALLK ddPTM_HeLa_Curcumin_4h_R1 1 AAAASAAEAGIATTGTEGERDSDDALLK 28 1 Q5VWC4 Q5VWC4 PSMD4 1 0 AAAASAAEAGIAT(0.098)T(0.098)GT(0.098)EGERDS(0.707)DDALLK 59.55 0.0012689 11745000 1700.7 1428.4 1639 1904.6 1709.2 2240.5 1886 1489.7 1888.4 1724.2 TRUE FALSE FALSE 1566.0878 1551.864531 1699.742782 1896.71927 1688.818906 1775.795044 1938.916084 1943.902672 1681.247245 1784.115822 0.877794917 0.86982275 0.952708765 1.063114427 0.946585914 0.99533619 1.086765815 1.089560806 0.942341985 1 10.80099356 -4.783919798 0.739670117 0.938913211 1.140561888 0.537960059 0.051207258 1.129047121 0.662170385 0.01091843 0.162277033 1.64E-05 4.783919798 0.201648676 AAAGEEETAAAGS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 1 AAAGEEETAAAGSPGR 16 0 Q9NS37;E9PIM0 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 1 0 AAAGEEET(0.001)AAAGS(0.999)PGR 73.758 0.020028 14233000 3023 2668 2641.2 2446.1 3029.9 3384.3 2822.7 3317.8 2886.2 2718.7 TRUE FALSE FALSE 2783.72636 2898.610032 2739.085195 2435.978686 2993.770421 2682.358031 2901.897365 4329.381947 2569.591081 2813.174623 0.989532018 1.03036975 0.97366341 0.865918051 1.064196441 0.953498588 1.031538299 1.538966658 0.913413288 1 11.45798339 -4.26220115 4.325742621 0.98942846 1.579253483 0.903889224 0.054753402 0.037008135 1.629187841 0.006251876 0.06680675 5.47E-05 4.26220115 0.589825024 AAAGEEETAAAGS(ph)PGRK ddPTM_HeLa_Curcumin_4h_R1 2 AAAGEEETAAAGSPGRK 17 1 Q9NS37;E9PIM0 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 1 0 AAAGEEETAAAGS(1)PGRK;AAAGEEETAAAGS(1)PGRK ; 102.24 0.00082415 84399000 7816.2 6050.9 6534.9 6775.3 6655.9 8590.6 6492.6 4746 7580.6 5786 TRUE FALSE FALSE 7197.539522 6573.912834 6777.089143 6747.265604 6576.53274 6808.812724 6674.764882 6193.033552 6749.027146 5987.063069 1.202182011 1.09801964 1.131955529 1.126974198 1.098457234 1.137254217 1.114864635 1.034402591 1.127268423 1 12.54763275 -9.575027351 1.367883712 1.000260654 1.129151902 0 0.055828487 0.26942931 0.906726568 0.031689165 0.007478326 2.66E-10 9.575027351 0.128891247 S(ph)IHVDSLEPQR ddPTM_HeLa_Curcumin_4h_R1 2 SIHVDSLEPQR 11 0 E7EVA0 E7EVA0 MAP4 Microtubule-associated protein 1 0 S(1)IHVDSLEPQR;S(1)IHVDSLEPQR ; 139.19 0.000694 15605700 4910.5 4031.1 4036.3 3982.2 4716.4 8769.9 7995.8 6559.3 6103.9 3703.2 TRUE FALSE FALSE 4521.828743 4379.530322 4185.888829 3965.722712 4660.16001 6950.923883 8220.140628 8559.200375 5434.317441 3831.885924 1.180053069 1.142917719 1.092383466 1.034927132 1.216153117 1.813969419 2.145194505 2.233678284 1.418183513 1 11.9038389 -5.119684562 1.973502251 1.08737356 2.214101008 0.930472222 0.116453723 0.036405018 0.269815594 0.011059967 0.040022606 7.59E-06 5.119684562 1.126727448 up S(ph)FEERVETTVTSLK ddPTM_HeLa_Curcumin_4h_R1 1 SFEERVETTVTSLK 14 1 E9PNK6;E9PPQ1;J3KNE7;Q16890-5;Q16890 E9PNK6 TPD52L1 Tumor protein D53 1 0 S(0.971)FEERVET(0.003)T(0.016)VT(0.009)S(0.001)LK 78.225 0.0090978 4978700 1094.3 498.62 719.44 664.45 668.53 3583.5 4292.4 2584.9 1133.1 782.82 TRUE FALSE FALSE 1007.685 541.718491 746.1030793 661.700682 660.5582164 2840.241706 4412.833192 3373.024111 1008.801765 810.0229367 1.244020329 0.668769323 0.92108883 0.81689129 0.815480879 3.506371952 5.447787947 4.164109382 1.245399012 1 9.66181895 -5.110626003 3.344442434 1.027322314 4.777957852 0.95078384 0.362615663 0.033421812 0.694464788 0.048658744 0.141139234 7.75E-06 5.110626003 3.750635538 up AAAGPLDMS(ph)LPSTPDIK ddPTM_HeLa_Curcumin_4h_R1 1 AAAGPLDMSLPSTPDIK 17 0 K7ELQ4;P17544-4;P17544-2;P17544 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 0 AAAGPLDMS(0.97)LPS(0.01)T(0.019)PDIK 115.23 0.0009838 12427000 3638.9 2702.7 3056 3034.2 3087.7 3462.6 2600.5 3666.3 3738.6 2575.2 TRUE FALSE FALSE 3350.877225 2936.309345 3169.258048 3021.645284 3050.881194 2744.417728 2673.463031 4784.137992 3328.484934 2664.688008 1.257512029 1.101933636 1.189354265 1.133958375 1.144929982 1.029920846 1.003293077 1.795383916 1.249108685 1 11.37975091 -1 0.020973595 2.30E-15 2.723537399 0.074171996 0.211695138 4288.849513 7.000815691 333.609424 616.4141213 0.1 1 2.723537399 AAAGPLDMSLPST(ph)PDIK ddPTM_HeLa_Curcumin_4h_R1 1 AAAGPLDMSLPSTPDIK 17 0 K7ELQ4;P17544-4;P17544-2;P17544 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 0 AAAGPLDMS(0.087)LPS(0.219)T(0.693)PDIK 132.51 0.0091786 7662800 3362.1 2758 2693.5 2956.3 2922.7 3070 2525 3363.8 3754.4 2836.4 TRUE FALSE FALSE 3095.986237 2996.389231 2793.323479 2944.067614 2887.848711 2433.247394 2595.844704 4389.407135 3342.551713 2934.964689 1.054863198 1.020928545 0.951740064 1.003101545 0.983946663 0.829055083 0.884455174 1.495557051 1.138872889 1 11.51912743 -4.25349397 24.99731491 0.996599844 1.495557293 0.776577486 0.081915904 339.5900501 1068370.555 0.010775681 0.158771694 5.58E-05 4.25349397 0.498957449 QLS(ph)EVFETEDSK ddPTM_HeLa_Curcumin_4h_R1 2 QLSEVFETEDSK 12 0 Q99618;F5GX58;F8WDL1 Q99618 CDCA3 Cell division cycle-associated protein 3 1 0 QLS(1)EVFETEDSK;QLS(0.984)EVFET(0.014)EDS(0.001)K ; 118.16 0.0037533 6268200 1944.83 1888.25 1599.96 1602.17 1689.4 3974.5 3848.9 2854.49 2010.62 1787.01 TRUE FALSE FALSE 1790.894653 2051.461916 1659.255925 1595.540645 1669.255008 3150.143898 3956.889775 3724.810861 1790.060016 1849.108464 0.968517903 1.109432981 0.897327527 0.862870229 0.902735043 1.70360147 2.139890575 2.014382029 0.968066531 1 10.85261414 -5.104764699 3.161702901 0.973006842 2.064405839 0.971620159 0.079326496 0.028832432 0.544243636 0.011844416 0.035100443 7.86E-06 5.104764699 1.091398997 up AAASK(ac)LEQGKR ddPTM_HeLa_Curcumin_4h_R1 2 AAASKLEQGKR 11 2 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 0 1 ; AAASK(1)LEQGKR;AAASK(1)LEQGKR 121.68 0.00042268 31096000 5673.7 4822.4 5273.3 4311 4574.8 6055.9 4142.5 5914.7 4947 4576.3 FALSE TRUE FALSE 5224.620658 5239.226768 5468.733137 4293.162224 4520.248498 4799.838076 4258.727401 7718.064802 4404.326477 4735.326084 1.103328591 1.106413091 1.154879947 0.906624411 0.954580195 1.013623558 0.89935251 1.629890881 0.930099934 1 12.20924806 -4.253354045 24.94373366 1.035040949 1.629891183 0.81378116 0.088427305 318.4076853 982283.4101 0.012051804 0.180969089 5.58E-05 4.253354045 0.594850234 AAASK(ac)LGEFAK ddPTM_HeLa_Curcumin_4h_R1 1 AAASKLGEFAK 11 1 P30153;C9J9C1;B3KQV6;P30154-4;P30154;P30154-3;P30154-2 P30153 PPP2R1A;PPP2R1B Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform;Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform 0 1 AAASK(1)LGEFAK 132.32 0.00068114 3308200 2491.4 1759.1 1396.9 1431.2 1536.8 1148.1 1057.1 580.4 1479.6 1493.7 FALSE TRUE FALSE 2294.203061 1911.148766 1448.670343 1425.278074 1518.474664 909.9711182 1086.759381 757.3612882 1317.291582 1545.605964 1.484338903 1.236504523 0.937283096 0.922148405 0.982446173 0.588747158 0.703128356 0.490009295 0.852281638 1 10.59395685 -5.701040117 0.866620974 1.227295136 0.553228461 0.54134326 0.188596388 0.336254693 0.461935038 0.036243449 0.134241946 1.99E-06 5.701040117 -0.674066675 DYGNS(ph)PLHR ddPTM_HeLa_Curcumin_4h_R1 2 DYGNSPLHR 9 0 A0A0U1RRM4;A0A0D9SF20;A0A087WUW5;K7ELW5;A6NLN1;P26599;P26599-2;P26599-3 A0A0U1RRM4;A6NLN1 PTBP1 Polypyrimidine tract-binding protein 1 1 0 DYGNS(1)PLHR;DYGNS(1)PLHR ; 108.68 0.004524 25376000 7973.2 7163.6 6800.9 7231.5 7802.8 13735.1 14972.3 10078.6 7300.2 5779.8 TRUE FALSE FALSE 7342.112807 7782.789664 7052.947337 7201.577969 7709.756706 10886.28543 15392.38244 13151.51874 6499.386324 5980.64762 1.22764511 1.301328913 1.179294917 1.204146846 1.289117366 1.82025194 2.573698272 2.199012478 1.086736209 1 12.546086 -5.095664712 2.183146144 1.140521205 2.396800065 0.933835928 0.128917207 0.055984204 0.51252895 0.020478132 0.071612032 8.02E-06 5.095664712 1.25627886 up AAATAEEPDPK ddPTM_HeLa_Curcumin_4h_R1 2 AAATAEEPDPK 11 0 C9J6D1;Q99733;Q99733-2;A8MXH2;E9PKT8;C9JZI7;H0YCI4 C9J6D1 NAP1L4 Nucleosome assembly protein 1-like 4 0 0 ; ; 154.85 2.36E-07 4635300 6401.3 4983 5687.5 5882.4 5536.3 6993.4 5810.7 6068.3 5810.4 5429.3 FALSE FALSE TRUE 5894.63035 5413.708316 5898.283753 5858.060187 5470.283238 5542.890008 5973.732603 7918.496735 5173.013657 5617.967771 1.049246025 0.963641754 1.049896332 1.042736524 0.973712108 0.986636135 1.06332625 1.409494867 0.92079803 1 12.45583263 -4.264420701 3.671260736 1.017324993 1.451259075 0.890655474 0.04257714 0.046429593 1.15092295 0.00436473 0.054594121 5.44E-05 4.264420701 0.433934083 AAATGNAS(ph)PGKLEHSK ddPTM_HeLa_Curcumin_4h_R1 2 AAATGNASPGKLEHSK 16 1 H0Y6H0;Q8NB78 H0Y6H0 KDM1B Lysine-specific histone demethylase 1B 1 0 AAAT(0.092)GNAS(0.904)PGKLEHS(0.004)K;AAAT(0.001)GNAS(0.993)PGKLEHS(0.006)K ; 68.639 0.011435 146686000 11897.6 8905.3 10080.5 12277.4 11314.2 12186.8 9311.5 6283.4 12563.3 10841 TRUE FALSE FALSE 10955.89241 9675.034451 10454.0922 12226.59937 11179.28555 9659.120306 9572.755629 8199.179735 11185.13742 11217.72394 0.976659121 0.862477495 0.93192632 1.08993584 0.996573424 0.861058835 0.853359886 0.730912953 0.997095086 1 13.45349236 -4.750799306 1.481206237 0.982246595 0.739102265 0.636450323 0.059204599 0.266300142 0.926918349 0.008991189 0.07271142 1.78E-05 4.750799306 -0.243144331 AAATPAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AAATPAKK 8 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 ; AAATPAK(1)K;AAATPAK(1)K 116.37 0.001051 34749000 22474 24838 19652.5 13673.3 15491.8 21944 16260.7 12324.1 14960.6 16711.9 FALSE TRUE FALSE 20695.15919 26984.88604 20380.83894 13616.72351 15307.0704 17392.56704 16716.93148 16081.66136 13319.45961 17292.63728 1.196761307 1.56048413 1.17858477 0.787428967 0.885178481 1.005778746 0.966708039 0.929971588 0.770238767 1 14.07787029 -6.278202043 24.7712478 1.143622604 0.921270148 0.258458324 0.191405502 738.4848742 1091304.018 0.02733142 0.041820789 5.27E-07 6.278202043 -0.222352456 AAATPESQEPQAK ddPTM_HeLa_Curcumin_4h_R1 2 AAATPESQEPQAK 13 0 P49006 P49006 MARCKSL1 MARCKS-related protein 0 0 ; ; 146.16 7.01E-16 0 272.11 281.55 212.71 364.94 436.83 242.69 185.21 200.22 241.997 0 FALSE FALSE TRUE 250.5722064 305.8859274 220.5932197 363.429975 431.6210876 192.3533583 190.4064941 261.2661563 215.4505345 0 0 AADAEAEVAS(ph)LNRR ddPTM_HeLa_Curcumin_4h_R1 2 AADAEAEVASLNRR 14 1 J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 J3KN67 TPM3 Tropomyosin alpha-3 chain 1 0 AADAEAEVAS(1)LNRR;AADAEAEVAS(1)LNRR ; 107.63 0.0015613 31384000 4282.7 3803.7 3304.8 4174.6 3573.9 4191 3956.6 3705.3 4134 3490 TRUE FALSE FALSE 3943.719776 4132.474879 3427.278795 4157.326611 3531.283577 3321.739358 4067.611547 4835.028913 3680.510543 3611.27724 1.092056775 1.144325014 0.949048928 1.151206716 0.977848928 0.919823967 1.126363687 1.338869489 1.019171417 1 11.81829347 -4.339966886 3.461152324 1.040796348 1.353634206 0.604772827 0.074702208 0.131561215 2.577117668 0.010253462 0.093206627 4.57E-05 4.339966886 0.312837859 AADAEAEVASLNRR ddPTM_HeLa_Curcumin_4h_R1 2 AADAEAEVASLNRR 14 1 J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 J3KN67 TPM3 Tropomyosin alpha-3 chain 0 0 ; ; 158.86 0.00047466 30651300 4144.2 3589.2 3372.4 3979.5 3191.8 4621.9 3618.2 3756.4 4244.6 3832.4 FALSE FALSE TRUE 3816.182197 3899.434455 3497.384111 3963.033883 3153.73987 3663.26584 3719.716954 4901.709068 3778.977999 3965.575615 0.962327432 0.98332117 0.881936054 0.999359051 0.795279217 0.923766483 0.938001772 1.236064961 0.952945642 1 11.95331458 -4.258919565 24.62337442 0.957842448 1.236065084 0.66852528 0.061593472 93.72964191 915845.6385 0.008920403 0.08075602 5.51E-05 4.258919565 0.278222636 AADEEAFEDNSEEYIR ddPTM_HeLa_Curcumin_4h_R1 1 AADEEAFEDNSEEYIR 16 0 P55060-4;P55060-3;P55060 P55060-4 CSE1L Exportin-2 0 0 143.31 0.0032465 15708000 1377.1 1321.8 1284.8 1243 1510.5 1450.2 1033.6 1025.2 1525.3 1485.7 FALSE FALSE TRUE 1268.101082 1436.050502 1332.415818 1237.856795 1492.488274 1149.412173 1062.600034 1337.778761 1357.978406 1537.327964 0.824873489 0.934121108 0.866708893 0.805200207 0.97083271 0.747668812 0.691199314 0.870197376 0.883336827 1 10.58620926 -13.52287875 0.149865858 1.611593714 0.772553688 0.203254441 0.081524234 49.00150716 0.500757858 8.888128144 0.178452723 3.00E-14 13.52287875 -0.839040026 AADEEAFEDNSEEYIRR ddPTM_HeLa_Curcumin_4h_R1 2 AADEEAFEDNSEEYIRR 17 1 P55060-4;P55060-3;P55060 P55060-4 CSE1L Exportin-2 0 0 ; ; 211.75 2.42E-11 129670000 4249.7 3749.7 3467.8 4213.5 3341.3 4462.2 3041.3 2667.62 4752.8 4429.5 FALSE FALSE TRUE 3913.331761 4073.80736 3596.319719 4196.065653 3301.45718 3536.689421 3126.630693 3480.965058 4231.429731 4583.424795 0.853800801 0.88881296 0.784635917 0.915486965 0.720303556 0.77162593 0.682160357 0.75946813 0.923202609 1 12.16221029 -5.352455453 0.048728565 1.54947752 3.42E-13 0.673816503 0.055151319 45.45597378 0.534909466 6.713907783 10.50417615 4.44E-06 5.352455453 -1.54947752 AADGGERPLAAS(ph)PPGTVK ddPTM_HeLa_Curcumin_4h_R1 1 AADGGERPLAASPPGTVK 18 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 0 AADGGERPLAAS(0.983)PPGT(0.017)VK 85.884 0.001889 20552000 3939.1 2767.5 3311.2 3406.5 3633.3 5246.3 3947.2 2358.8 3633.8 3191.9 TRUE FALSE FALSE 3627.316078 3006.710368 3433.915985 3392.404806 3589.97527 4158.158242 4057.947809 3077.987261 3235.181231 3302.818287 1.098248757 0.910346894 1.039692676 1.027124265 1.086943016 1.258972756 1.22863187 0.931927522 0.979521412 1 11.68948188 -5.513166396 9.961014435 1.035253039 1.152782811 0.254276405 0.094768959 0.245651818 225.5884116 0.013264792 0.02804506 3.07E-06 5.513166396 0.117529772 AADIS(ph)LDNLVEGK ddPTM_HeLa_Curcumin_4h_R1 3 AADISLDNLVEGK 13 0 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 AADIS(1)LDNLVEGK;AADIS(1)LDNLVEGK;AADIS(1)LDNLVEGK ;; 172.1 0.0002021 69670000 8822.8 7875.1 7732.8 8341.2 8044.9 12803.3 11533.3 5323.4 9188.5 6376.7 TRUE FALSE FALSE 8124.46607 8555.788553 8019.38437 8306.686325 7948.969822 10147.75126 11856.89336 6946.480154 8180.544538 6598.28985 1.231298754 1.296667583 1.215373158 1.258915039 1.204701521 1.53793657 1.796964612 1.05276978 1.239797694 1 12.68787644 -7.647190094 0.164581729 0.810442499 1.607830752 0.147177893 0.201957174 3.164421652 0.445243772 1.033782444 0.865960648 2.25E-08 7.647190094 0.797388254 AADKS(ph)PESQNLIDGTK ddPTM_HeLa_Curcumin_4h_R1 1 AADKSPESQNLIDGTK 16 1 Q9HCE3 Q9HCE3 ZNF532 Zinc finger protein 532 1 0 AADKS(0.909)PES(0.091)QNLIDGTK 129.05 0.0045255 17667000 3244.4 2480.7 2423.1 2937.1 3110.8 3117.3 2742.2 1398.3 2798.4 2432.7 TRUE FALSE FALSE 2987.602317 2695.120654 2512.902218 2924.947058 3073.705742 2470.736841 2819.138752 1824.635233 2491.422521 2517.236144 1.186858183 1.070666596 0.9982783 1.161967686 1.221063725 0.981527636 1.119934162 0.7248566 0.989745252 1 11.29762485 -4.258611032 24.36045287 1.090954429 0.724856407 0.613217276 0.084557297 97.79853418 842266.8494 0.012376703 0.114604002 5.51E-05 4.258611032 -0.366098022 AADPPAENSS(ph)APEAEQGGAE ddPTM_HeLa_Curcumin_4h_R1 2 AADPPAENSSAPEAEQGGAE 20 0 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 0 AADPPAENS(0.183)S(0.817)APEAEQGGAE;AADPPAENS(0.086)S(0.914)APEAEQGGAE ; 164.2 4.71E-06 154537000 17402.9 15719.3 15031.9 16672.5 15352.5 18875.5 15158.8 12279.8 18644.9 15491.8 TRUE FALSE FALSE 16025.4421 17078.00625 15588.99544 16603.51361 15169.43146 14960.50853 15584.11513 16023.85449 16599.60112 16030.1389 0.999707002 1.065368576 0.972480372 1.035768543 0.946306926 0.933273793 0.972175926 0.999607963 1.035524472 1 13.96849931 -5.748706059 24.99971273 1.00527974 0.961395964 0.408330401 0.030306127 192.931046 378784.894 0.00401596 0.007990667 1.78E-06 5.748706059 -0.043883776 AADPPAENSSAPEAEQGGAE ddPTM_HeLa_Curcumin_4h_R1 3 AADPPAENSSAPEAEQGGAE 20 0 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 0 ;; ;; 225.31 3.71E-28 40962300 11811 9921.12 9500.81 9977.15 10847.77 12706.71 10214.1 9739.3 12211.83 9737.9 FALSE FALSE TRUE 10876.14689 10778.65741 9852.918376 9935.867197 10718.41743 10071.19511 10500.68016 12708.76774 10872.2228 10076.2913 1.079379959 1.069704823 0.977831831 0.98606391 1.063726435 0.99949424 1.042117565 1.261254499 1.078990521 1 13.29867711 -4.26275322 5.47980361 1.032070094 1.269550241 0.770236331 0.037429675 0.055795198 6.385975511 0.005588212 0.04950603 5.46E-05 4.26275322 0.237480148 AKPS(ph)PAPPSTTTAPDASGPQKR ddPTM_HeLa_Curcumin_4h_R1 1 AKPSPAPPSTTTAPDASGPQKR 22 2 Q5QNY5;P40855;E9PS71;B7Z8B3 Q5QNY5 PEX19 Peroxisomal biogenesis factor 19 1 0 AKPS(1)PAPPSTTTAPDASGPQKR 78.708 0.00027011 7559900 2414.1 1724.3 2110.3 2397.8 2164.7 4099.5 4505.8 3077.2 2129 1635.6 TRUE FALSE FALSE 2223.021438 1873.340809 2188.509574 2387.878539 2138.887366 3249.217489 4632.220621 4015.424114 1895.454026 1692.436978 1.31350323 1.106889552 1.293111414 1.410911348 1.26379144 1.919845484 2.737012179 2.372569358 1.119955455 1 10.7248864 -5.071468487 2.262829612 1.17952313 2.569057158 0.928331926 0.149755126 0.059619758 0.589059941 0.024663942 0.086640516 8.48E-06 5.071468487 1.389534027 up AADS(ph)DDGAVSAPAASDGGVSK ddPTM_HeLa_Curcumin_4h_R1 7 AADSDDGAVSAPAASDGGVSK 21 0 Q96GM8 Q96GM8 TOE1 Target of EGR1 protein 1 1 0 AADS(1)DDGAVSAPAASDGGVSK;AADS(1)DDGAVSAPAASDGGVSK;AADS(1)DDGAVSAPAASDGGVSK;AADS(1)DDGAVSAPAASDGGVSK;AADS(1)DDGAVSAPAASDGGVSK;AADS(1)DDGAVSAPAASDGGVSK;AADS(1)DDGAVSAPAASDGGVSK ;;;;;; 262.37 2.31E-59 604197400 20893.19 17868.25 18673.67 19316.47 19190.32 22940.14 17065.75 14756.47 21937.22 20399.59 TRUE FALSE FALSE 19239.47197 19412.70191 19365.73264 19236.54357 18961.48797 18182.09638 17544.56901 19255.64977 19530.76185 21108.47423 0.911457254 0.919663908 0.91743877 0.911318523 0.898287946 0.861364785 0.831162348 0.912223667 0.92525692 1 14.36553468 -13.52287875 0.111795559 1.374832999 0.825165806 0.399329454 0.032137333 31.83452258 0.260674902 2.703763964 0.133847383 3.00E-14 13.52287875 -0.549667193 AADTEEMDIEMDS(ph)GDEA ddPTM_HeLa_Curcumin_4h_R1 1 AADTEEMDIEMDSGDEA 17 0 Q9UBB5 Q9UBB5 MBD2 Methyl-CpG-binding domain protein 2 1 0 AADTEEMDIEMDS(1)GDEA 63.694 0.012259 5913600 1939.1 1465.8 1802.7 2029 1663.1 2291.1 2139.8 1947.2 1928.7 1663.5 TRUE FALSE FALSE 1785.618189 1592.497221 1869.509648 2020.604536 1643.268619 1815.900034 2199.837029 2540.892316 1717.126435 1721.306501 1.037362136 0.925167725 1.08609922 1.173878408 0.954663575 1.054954497 1.278004253 1.476141707 0.997571574 1 10.7492883 -4.551080529 2.147849082 1.023232027 1.490566496 0.831814592 0.065735284 0.110924586 0.841054804 0.009221089 0.078618807 2.81E-05 4.551080529 0.467334469 AAEAAAAPAESAAPAAGEEPSKEEGEPK ddPTM_HeLa_Curcumin_4h_R1 1 AAEAAAAPAESAAPAAGEEPSKEEGEPK 28 1 P80723 P80723 BASP1 Brain acid soluble protein 1 0 0 222.54 1.18E-34 1853200 933.96 604.62 906.33 885.94 791.6 1510 858.44 991.18 1050.1 843.92 FALSE FALSE TRUE 860.0360805 656.8806587 939.9193871 882.274215 782.160687 1196.808979 882.525516 1293.386219 934.9066572 873.2461572 0.984872448 0.752228513 1.076351014 1.010338503 0.895693248 1.370528767 1.010626281 1.481124433 1.070610674 1 9.770244579 -1 0.594193905 0.976731908 28.95139889 0.500006169 0.14313327 86.56541138 0.629100807 0.022570021 3148.52464 0.1 1 27.97466699 AAEAGGAEEQYGFLT(ph)TPTK ddPTM_HeLa_Curcumin_4h_R1 2 AAEAGGAEEQYGFLTTPTK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 AAEAGGAEEQYGFLT(0.542)T(0.441)PT(0.018)K;AAEAGGAEEQYGFLT(0.58)T(0.42)PTK ; 185.63 3.18E-07 285680000 14012.1 14038.82 12895.6 13102.63 12955.87 16821.8 13605.4 15130.3 15734.2 12464.18 TRUE FALSE FALSE 12903.0275 15252.27305 13373.52228 13048.41479 12801.37971 13332.76906 13987.13091 19743.45882 14008.19763 12897.30933 1.000443362 1.182593412 1.036923434 1.011716045 0.992562044 1.033763611 1.084499918 1.530819981 1.086133338 1 13.6547825 -4.240522685 2.929792328 1.018228905 1.633015094 0.85996029 0.058011167 0.105772388 1.234080738 0.007916523 0.156238622 5.75E-05 4.240522685 0.614786189 AAEAGGAEEQYGFLTT(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 6 AAEAGGAEEQYGFLTTPTK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 AAEAGGAEEQYGFLT(0.138)T(0.846)PT(0.016)K;AAEAGGAEEQYGFLT(0.156)T(0.603)PT(0.241)K;AAEAGGAEEQYGFLT(0.02)T(0.923)PT(0.057)K;AAEAGGAEEQYGFLT(0.03)T(0.97)PTK;AAEAGGAEEQYGFLT(0.013)T(0.968)PT(0.019)K;AAEAGGAEEQYGFLT(0.209)T(0.791)PTK ;;;;; 206.81 3.04E-38 699955000 24367.1 20381.5 21140.8 21414.1 20063.3 28446.9 21770.9 24443.4 24854 20086.9 TRUE FALSE FALSE 22438.41832 22143.18604 21924.29665 21325.49413 19824.05825 22546.69228 22381.73286 31896.08014 22127.57838 20784.91828 1.079552877 1.065348718 1.054817553 1.026008081 0.953771287 1.084762133 1.076825637 1.534578087 1.064597805 1 14.34324946 -4.246091181 3.532333148 1.037980969 1.602478289 0.937466605 0.038010291 0.059592632 1.260528987 0.00591659 0.09073577 5.67E-05 4.246091181 0.56449732 AAECNIVVTQPR ddPTM_HeLa_Curcumin_4h_R1 2 AAECNIVVTQPR 12 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 0 ; ; 152.67 2.90E-05 5272400 1596.73 1375.92 1319.66 1637.1 1253.23 1921.8 1398.97 1194.58 1532.21 1489.34 FALSE FALSE TRUE 1470.347136 1494.848394 1368.56776 1630.326114 1238.286051 1523.197017 1438.221333 1558.801943 1364.130396 1541.094454 0.954092808 0.969991417 0.888049241 1.057901487 0.803510808 0.988386541 0.933246713 1.011490203 0.885169882 1 10.58973957 -8.891863642 0.605099744 1.003020929 0.947251408 0 0.074581467 1.813416591 1.169958512 0.052397117 0.014360801 1.28E-09 8.891863642 -0.055769521 AAEDDEDDDVDTK ddPTM_HeLa_Curcumin_4h_R1 5 AAEDDEDDDVDTK 13 0 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA "Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1" 0 0 ;;;; ;;;; 325.73 6.50E-134 2004857000 16187.6 14058.6 14710 15360.2 15388.8 17006 14713 14193.6 16152.6 13707.3 FALSE FALSE TRUE 14906.33438 15273.76274 15255.16554 15296.64356 15205.29861 13478.7639 15125.80718 18521.1633 14380.70019 14183.62765 1.050953588 1.076858693 1.075547519 1.078471879 1.07203171 0.950304409 1.06642726 1.305812853 1.013894368 1 13.79193895 -4.273390323 4.277119098 1.034604552 1.323718268 0.797378326 0.039882693 0.067432914 2.833251725 0.005937061 0.058026665 5.33E-05 4.273390323 0.289113716 AAEDDEDDDVDTK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AAEDDEDDDVDTKK 14 1 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA "Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1" 0 1 ; AAEDDEDDDVDTK(1)K;AAEDDEDDDVDTK(1)K 336.93 6.33E-204 27057100 7119.7 7235.7 6868.8 6538.3 9328.6 12076.1 8923.3 9550.5 10545.6 6286.8 FALSE TRUE FALSE 6556.168232 7861.121666 7123.36377 6511.246247 9217.362538 9571.380734 9173.663782 12462.40348 9388.774064 6505.265832 1.007824799 1.208424355 1.095015016 1.000919319 1.416907898 1.471328149 1.410190455 1.915740849 1.443257556 1 12.6673923 -1 0.339279719 0.98765297 10.73832423 0.591812794 0.177280544 12.23504758 0.154467664 0.031065992 76.54210655 0.1 1 9.750671257 AAEDDEDDDVDTKK ddPTM_HeLa_Curcumin_4h_R1 5 AAEDDEDDDVDTKK 14 1 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA "Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1" 0 0 ;;;; ;;;; 226.28 1.71E-19 90502000 16678.9 14466.9 15798.6 16264.8 15147 18501.2 15292.2 15260.6 17573.3 14109.6 FALSE FALSE TRUE 15358.74747 15717.35437 16384.11001 16197.50057 14966.38192 14663.84257 15721.25798 19913.48669 15645.55296 14599.90755 1.051975666 1.076537938 1.122206422 1.109424872 1.025101143 1.004379139 1.07680531 1.363946081 1.071620002 1 13.83367161 -4.26623889 3.859808694 1.040670353 1.394059507 0.826851567 0.041243815 0.077902145 2.289344805 0.0066292 0.077029613 5.42E-05 4.26623889 0.353389154 AAEDS(ph)PYWVSPAYSK ddPTM_HeLa_Curcumin_4h_R1 1 AAEDSPYWVSPAYSK 15 0 Q9NW82 Q9NW82 WDR70 WD repeat-containing protein 70 1 0 AAEDS(0.999)PYWVS(0.001)PAYSK 141.82 0.00052265 6864800 1676.7 1274.5 1130.8 1631.5 1769.3 2490.1 2183.1 652.46 1585 1331.4 TRUE FALSE FALSE 1543.987426 1384.662101 1172.708443 1624.749285 1748.202253 1973.625191 2244.35191 851.3920504 1411.129465 1377.666051 1.120726917 1.00507819 0.851228381 1.179349149 1.268959377 1.432586068 1.629097203 0.617995958 1.024289932 1 10.4280105 -6.019688161 7.322090686 1.038547192 1.272948953 0.157610972 0.250198432 0.233269185 60.61516727 0.0349642 0.059960561 9.56E-07 6.019688161 0.234401762 AAEDSPYWVS(ph)PAYSK ddPTM_HeLa_Curcumin_4h_R1 2 AAEDSPYWVSPAYSK 15 0 Q9NW82 Q9NW82 WDR70 WD repeat-containing protein 70 1 0 AAEDS(0.008)PY(0.002)WVS(0.99)PAYSK;AAEDS(0.002)PYWVS(0.998)PAYSK ; 208.39 9.91E-10 29020600 8763.7 6418.5 7341.9 7706.7 8204 13868.9 12449.2 5052.2 9030 6315.5 TRUE FALSE FALSE 8070.043898 6973.28654 7613.997273 7674.811717 8106.172658 10992.33381 12798.49105 6592.592523 8039.431592 6534.963155 1.234902739 1.067073582 1.165117093 1.174423105 1.240431272 1.682080456 1.958464148 1.008818622 1.23021835 1 12.67396339 -5.413316967 3.81613953 1.120444891 1.588170717 0.374540757 0.230509998 0.155718598 4.027450728 0.03138533 0.073274449 3.86E-06 5.413316967 0.467725826 AAEEAFVNDIDESS(ph)PGTEWER ddPTM_HeLa_Curcumin_4h_R1 2 AAEEAFVNDIDESSPGTEWER 21 0 P09496-2;P09496-5 P09496-2 CLTA Clathrin light chain A 1 0 AAEEAFVNDIDES(0.029)S(0.971)PGTEWER;AAEEAFVNDIDES(0.005)S(0.995)PGTEWER ; 239.09 7.02E-38 26503000 7381.4 5286.2 5707 6464.3 6428.3 8331.6 7403.8 8171.4 7126.7 5820 TRUE FALSE FALSE 6797.154401 5743.115573 5918.50644 6437.552439 6351.646721 6603.532244 7611.530702 10662.82224 6344.91884 6022.244567 1.128674587 0.953650339 0.982774176 1.068962306 1.054697572 1.096523426 1.263902623 1.77057277 1.0535804 1 12.55608558 -4.138618014 1.542824558 1.047808637 2.216137297 0.955499186 0.047814932 0.264878917 0.461096205 0.00877778 0.509306174 7.27E-05 4.138618014 1.16832866 AAEEAFVNDIDESSPGTEWER ddPTM_HeLa_Curcumin_4h_R1 2 AAEEAFVNDIDESSPGTEWER 21 0 P09496-2;P09496-5 P09496-2 CLTA Clathrin light chain A 0 0 ; ; 313.87 1.11E-118 10966400 3973.9 3592.7 3563.22 3715.16 3740.74 4530.5 3634.89 3323.51 4139.73 3538.53 FALSE FALSE TRUE 3659.361622 3903.236979 3695.276068 3699.787652 3696.134119 3590.823231 3736.875231 4336.832899 3685.611976 3661.493654 0.999417715 1.066023145 1.009226402 1.010458573 1.009460747 0.980699018 1.020587657 1.184443648 1.006587017 1 11.83821658 -4.26505703 4.379818207 1.005417814 1.196720174 0.858767645 0.0210155 0.051214473 2.363572642 0.002936585 0.030160884 5.43E-05 4.26505703 0.191302359 AAEEEDEADPK ddPTM_HeLa_Curcumin_4h_R1 1 AAEEEDEADPK 11 0 P20962 P20962 PTMS Parathymosin 0 0 117.52 0.0024272 1226100 407.26 174.75 257.31 298.96 164.07 254.31 454.55 261.11 342.66 179.85 FALSE FALSE TRUE 375.0249413 189.8546113 266.846135 297.7229827 162.1135724 201.5632393 467.3034496 340.721237 305.0710553 186.0997741 2.015182141 1.020176474 1.433887474 1.599803031 0.871111065 1.083092337 2.511037167 1.830852502 1.639287617 1 7.539932494 -4.762622672 24.99999994 1.396829776 2.170944874 0.43991842 0.372719262 26.05878893 550622.2578 0.063219283 0.206637991 1.73E-05 4.762622672 0.774115098 AAEEEDEADPK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 AAEEEDEADPKR 12 1 P20962 P20962 PTMS Parathymosin 0 1 ; AAEEEDEADPK(1)R;AAEEEDEADPK(1)R 163.84 1.50E-06 8371500 2799.8 3565.1 2910.8 2375.8 4893.8 6208.5 4735.2 4902 5825.2 2771.12 FALSE TRUE FALSE 2578.192876 3873.251358 3018.676809 2365.969569 4835.444631 4920.787116 4868.056968 6396.597234 5186.190134 2867.416214 0.899134511 1.350781006 1.052751531 0.825122477 1.686342083 1.716104935 1.697715506 2.230787844 1.808663182 1 11.48553562 -5.06584991 0.689911729 0.962346253 2.298019309 0.431111336 0.336039436 0.421842674 0.25007891 0.035935731 0.356943259 8.59E-06 5.06584991 1.335673056 AAEEEDEADPKR ddPTM_HeLa_Curcumin_4h_R1 3 AAEEEDEADPKR 12 1 P20962 P20962 PTMS Parathymosin 0 0 ;; ;; 106.16 0.0098498 160843000 7378.3 5331.48 6017.7 6561.67 5858 7014.8 6069 6118.4 6751.2 6103.8 FALSE FALSE TRUE 6794.299769 5792.309375 6240.721256 6534.519548 5788.147176 5559.851407 6239.279806 7983.871994 6010.610251 6315.906596 1.075744181 0.917098644 0.988095875 1.034613076 0.916439641 0.880293482 0.98786765 1.264089624 0.951662308 1 12.62477412 -7.296818097 24.93453511 1.035768079 0.991261624 0 0.104737599 1691.38694 1192067.445 0.017298571 0.019782065 5.05E-08 7.296818097 -0.044506456 AAEEPSK(ac)VEEK ddPTM_HeLa_Curcumin_4h_R1 2 AAEEPSKVEEK 11 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 0 1 ; AAEEPSK(1)VEEK;AAEEPSK(1)VEEK 101.65 0.00053825 6696100 4957.4 7017 4774.8 4494.4 10307.3 13446.9 10002.1 9085.7 12668.8 4938.6 FALSE TRUE FALSE 4565.016559 7623.518213 4951.758288 4475.803364 10184.39218 10657.86136 10282.73201 11855.8881 11279.06434 5110.215982 0.893311863 1.491819179 0.968991977 0.87585405 1.992947503 2.085599004 2.012191274 2.320036598 2.207160005 1 12.31916855 -5.725798519 6.114218552 0.990263496 2.105177591 0.438306107 0.426507218 0.041694957 4.227502329 0.027324516 0.054292886 1.88E-06 5.725798519 1.114914095 AAEEPSKVEEK ddPTM_HeLa_Curcumin_4h_R1 1 AAEEPSKVEEK 11 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 0 0 80.834 0.02022 11208000 4291.5 3231.1 3553.9 3502.3 4716.8 5369.2 3830.8 4013.8 5027.9 4315.9 FALSE FALSE TRUE 3951.823247 3510.381886 3685.61066 3487.808411 4660.555241 4255.567397 3938.281938 5237.589143 4476.351949 4465.877204 0.884892949 0.786045322 0.82528258 0.780990666 1.04359234 0.952907391 0.881860776 1.172801872 1.002345507 1 12.12472787 -4.256268807 24.61641628 0.918815476 1.172802004 0.444152704 0.088424038 358.591138 1707136.567 0.013137949 0.145881941 5.54E-05 4.256268807 0.253986529 AAEEQGDDQDS(ph)EKSKPAGSDGER ddPTM_HeLa_Curcumin_4h_R1 2 AAEEQGDDQDSEKSKPAGSDGER 23 2 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 0 AAEEQGDDQDS(0.989)EKS(0.011)KPAGSDGER;AAEEQGDDQDS(0.96)EKS(0.039)KPAGSDGER ; 105.52 1.71E-05 48346000 5438.9 4755.4 4737.5 5052 5688.5 6208.5 5163.1 4804.1 5051.7 4573.4 TRUE FALSE FALSE 5008.405326 5166.435586 4913.075918 5031.096163 5620.668353 4920.787116 5307.96269 6268.847975 4497.541149 4732.32531 1.058339188 1.091732974 1.038194882 1.063134048 1.187718085 1.039824356 1.121639436 1.324686611 0.950387147 1 12.20833354 -1 0.465394293 1.032420503 7.398084862 0.66829204 0.057619639 34.76014092 0.362814544 0.010985363 213.918519 0.1 1 6.36566436 AAEEQGDDQDSEKSKPAGS(ph)DGERR ddPTM_HeLa_Curcumin_4h_R1 1 AAEEQGDDQDSEKSKPAGSDGERR 24 3 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 0 AAEEQGDDQDS(0.006)EKS(0.202)KPAGS(0.792)DGERR 50.255 0.011384 1416100 182.47 0 168.98 215.84 200.07 170.65 218.52 192.52 199.86 197.27 TRUE FALSE FALSE 168.027307 0 175.2425474 214.9469113 197.6842959 135.2552664 224.6510831 251.2184617 177.935858 204.1251178 0.823158408 0 0.858505554 1.053015492 0.968446696 0.662609618 1.100555804 1.230708227 0.871699965 1 7.673309908 -6.365890753 7.159255259 0.826498586 0.987106045 0.139786293 0.299658176 0.69107791 41.70937469 0.05013177 0.076710805 4.31E-07 6.365890753 0.160607459 AAEK(ac)RPAEDYVPR ddPTM_HeLa_Curcumin_4h_R1 2 AAEKRPAEDYVPR 13 2 Q969E4;Q5H9L2 Q969E4 TCEAL3;TCEAL5 Transcription elongation factor A protein-like 3;Transcription elongation factor A protein-like 5 0 1 ; AAEK(1)RPAEDYVPR;AAEK(1)RPAEDYVPR 124.38 0.00028717 26848000 8478.2 8474.2 8482.5 7911.4 7296.9 9291.4 6084.8 7251.1 8380.8 7919.7 FALSE TRUE FALSE 7807.141524 9206.672088 8796.868912 7878.664723 7209.889233 7364.258904 6255.523112 9461.92701 7461.447208 8194.908986 0.952681907 1.123462396 1.073455352 0.961409668 0.879801014 0.898638279 0.763342598 1.154610384 0.910497874 1 13.00051221 -5.983543568 8.912627074 0.997766423 0.911878375 0.121530931 0.106474714 0.315806256 144.5220725 0.01461322 0.026263087 1.04E-06 5.983543568 -0.085888048 AAEK(ac)VSEAR ddPTM_HeLa_Curcumin_4h_R1 2 AAEKVSEAR 9 1 O75348 O75348 ATP6V1G1 V-type proton ATPase subunit G 1 0 1 ; AAEK(1)VSEAR;AAEK(1)VSEAR 107.21 0.00031026 0 3234.8 2593.4 2850 2775.83 2866.9 3461.5 3053.5 3170.6 3106.3 2874.76 FALSE TRUE FALSE 2978.762167 2817.56194 2955.623507 2764.344351 2832.71409 2743.545881 3139.172992 4137.301344 2765.546662 2974.657696 1.001379813 0.947188627 0.993601217 0.929298304 0.952282373 0.922306417 1.055305623 1.390849559 0.929702488 1 11.53850795 -4.27986748 3.317187122 0.983584109 1.437723691 0.926256393 0.035966939 0.056371296 1.020707135 0.004976679 0.063454098 5.25E-05 4.27986748 0.454139583 AAEK(ac)VSR ddPTM_HeLa_Curcumin_4h_R1 1 AAEKVSR 7 1 Q14676;Q14676-3;Q14676-2;Q14676-4;H0Y6Z8 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 0 1 AAEK(1)VSR 111.17 0.012899 5893800 1451.1 1747.8 1247.8 1246.4 1453.8 1934.3 1758.9 1627.1 1361.1 1654.1 FALSE TRUE FALSE 1336.243904 1898.872044 1294.044566 1241.242727 1436.464385 1533.104376 1808.25 2123.1953 1211.790735 1711.579852 0.780707895 1.1094265 0.756052698 0.725202932 0.839262266 0.895724716 1.056480069 1.240488603 0.707995443 1 10.74111289 -4.480860451 2.196643852 0.882541163 1.260654987 0.501032075 0.122167794 0.289307417 2.159021741 0.01743084 0.17674339 3.30E-05 4.480860451 0.378113825 AAELETDIR ddPTM_HeLa_Curcumin_4h_R1 1 AAELETDIR 9 0 O94906-2;O94906 O94906-2 PRPF6 Pre-mRNA-processing factor 6 0 0 92.925 0.017385 3604100 2746.6 3192.6 2036.8 2639 3626 6188.8 2841.7 2469 3209.1 2407.1 FALSE FALSE TRUE 2529.203712 3468.554118 2112.2856 2628.080517 3582.762318 4905.173118 2921.430454 3221.786734 2857.069759 2490.746546 1.015440016 1.392576103 0.848053208 1.055137674 1.438429102 1.969358595 1.172913582 1.29350244 1.147073661 1 11.28236251 -5.752062088 5.390003828 1.028423523 1.487245259 0.393346368 0.23443939 0.114071612 9.914536572 0.032946338 0.064271458 1.77E-06 5.752062088 0.458821736 (ac)GT(ph)PQKDVIIKSDAPDTLLLEK ddPTM_HeLa_Curcumin_4h_R1 2 GTPQKDVIIKSDAPDTLLLEK 21 2 Q5T4U8;P53611 Q5T4U8 RABGGTB Geranylgeranyl transferase type-2 subunit beta 1 0 GT(0.992)PQKDVIIKS(0.008)DAPDTLLLEK;GT(0.938)PQKDVIIKS(0.061)DAPDT(0.002)LLLEK ; 56.748 0.00078885 38903000 7101.5 4719.3 3900.9 5462.9 2077.84 7536.6 3748.9 2718.9 12015.1 8918.7 TRUE FALSE FALSE 6539.408782 5127.215263 4045.470786 5440.295967 2053.063115 5973.424205 3854.084044 3547.880094 10697.07359 9228.624161 0.708600618 0.555577427 0.438361203 0.589502387 0.222466868 0.64727137 0.41762282 0.384443015 1.159118998 1 13.17189987 -7.845712775 0.500459137 0.996808362 0.417205205 0.785570835 0.125592139 0.251011552 0.153601457 0.056023191 0.039415464 1.43E-08 7.845712775 -0.579603156 AAESETPGK(ac)SPEK ddPTM_HeLa_Curcumin_4h_R1 2 AAESETPGKSPEK 13 1 O76021;O76021-2;J3QSV6 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 0 1 ; AAESETPGK(1)SPEK;AAESETPGK(1)SPEK 178.53 1.35E-08 3020200 1803.92 1935.52 1656.67 1536.78 2102.69 2479.35 2001.25 1570.06 2301.56 1539.61 FALSE TRUE FALSE 1661.137829 2102.817724 1718.067648 1530.421212 2077.616795 1965.104862 2057.399689 2048.764066 2049.084626 1593.111333 1.042700403 1.319943987 1.078435394 0.960649253 1.3041253 1.233501276 1.291434972 1.28601437 1.286215586 1 10.63763138 -3.911687627 0.197916708 0.962954679 1.674235437 0 0.137306182 10.49247066 0.332632768 0.131621209 1.903494485 0.00012255 3.911687627 0.711280758 AAESETPGKS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 2 AAESETPGKSPEK 13 1 O76021;O76021-2;J3QSV6 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 0 AAES(0.009)ET(0.15)PGKS(0.841)PEK;AAES(0.017)ET(0.027)PGKS(0.957)PEK ; 140.03 0.0094768 92327000 5399.3 5181.4 5420.5 5307.8 5492.5 5524.6 5004 2052.84 4029 3788.4 TRUE FALSE FALSE 4971.939708 5629.257128 5621.388498 5285.83773 5427.005525 4378.735685 5144.398772 2678.741466 3587.02878 3920.046618 1.268336883 1.436017904 1.434010624 1.348411957 1.384423721 1.117011126 1.312331019 0.683344288 0.91504748 1 11.9366551 -2.968213319 13.89889039 1.187645446 1.181251362 0 0.240382855 0 0 0.031031171 0 0.001075937 2.968213319 -0.006394084 AAESETPGKS(ph)PEKKPK ddPTM_HeLa_Curcumin_4h_R1 1 AAESETPGKSPEKKPK 16 3 O76021;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 0 AAES(0.003)ET(0.003)PGKS(0.995)PEKKPK 65.905 0.01481 1077700000 11805 9908.7 11085 11130 9740.4 12791 8586.9 4131.3 12824 9597.9 TRUE FALSE FALSE 10870.62179 10765.16388 11495.81985 11083.94701 9624.252092 10138.00242 8827.825304 5390.914352 11417.23928 9931.426311 1.094568036 1.083949429 1.157519524 1.116047853 0.969070483 1.020800245 0.888877894 0.542813709 1.149607209 1 13.27778521 -3.983809683 1.229700727 1.059150836 9.43E-13 0.887726437 0.05797384 0.644910148 0.521103672 0.008901737 1.017600607 0.000103798 3.983809683 -1.059150836 AAESETPGKSPEK(ac)KPK ddPTM_HeLa_Curcumin_4h_R1 1 AAESETPGKSPEKKPK 16 3 O76021;O76021-2 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 0 1 AAESETPGKSPEK(0.5)K(0.5)PK 62.237 0.014939 7857500 890.9 834.79 871.54 966.82 905.94 1605.7 910.74 1002.3 1994.7 1302.7 FALSE TRUE FALSE 820.3843249 906.9455278 903.8400391 962.819555 895.1372572 1272.65972 936.2929133 1307.896656 1775.8864 1347.968728 0.608607832 0.672823864 0.670520035 0.7142744 0.664063816 0.944131487 0.694595426 0.970272254 1.317453709 1 10.39657131 -9.481377557 1.236938858 0.999229574 0.725537563 0.469940771 0.155714682 0.347619383 0.955826808 0.07976525 0.019753903 3.30E-10 9.481377557 -0.273692011 AAFTTPDHAPLS(ph)PQSSVASSGSEQTEEQGSSR ddPTM_HeLa_Curcumin_4h_R1 2 AAFTTPDHAPLSPQSSVASSGSEQTEEQGSSR 32 0 A0A087WZT0;M0QZ22;Q5PRF9;M0R0X3 A0A087WZT0 SAMD4B Protein Smaug homolog 2 1 0 AAFTTPDHAPLS(0.98)PQS(0.019)S(0.001)VASSGSEQTEEQGSSR;AAFTTPDHAPLS(0.848)PQS(0.136)S(0.016)VASSGSEQTEEQGSSR ; 148.84 1.68E-13 36554000 3734.1 2833.3 3053.6 3262.1 3395 4771.3 3665.1 4139.3 3886 3521.2 TRUE FALSE FALSE 3438.542045 3078.197827 3166.769102 3248.602295 3354.516842 3781.678596 3767.932842 5401.353515 3459.715522 3643.561438 0.943731045 0.844832146 0.869141129 0.8916008 0.920669762 1.037907185 1.03413457 1.482437886 0.949542249 1 11.8311336 -3.798721216 1.389236254 0.947449969 2.50978558 0.899866729 0.054830458 1.0470177 0.739469709 0.009543901 3.138788961 0.000158957 3.798721216 1.562335611 AAFTTPDHAPLSPQS(ph)SVASSGSEQTEEQGSSR ddPTM_HeLa_Curcumin_4h_R1 1 AAFTTPDHAPLSPQSSVASSGSEQTEEQGSSR 32 0 A0A087WZT0;M0QZ22;Q5PRF9;M0R0X3 A0A087WZT0 SAMD4B Protein Smaug homolog 2 1 0 AAFTTPDHAPLS(0.242)PQS(0.299)S(0.299)VAS(0.054)S(0.053)GS(0.013)EQT(0.013)EEQGS(0.013)S(0.013)R 41.89 0.014362 41780000 735.93 564.81 881.78 848.39 830.46 999.3 570.16 937.52 751.22 926.6 TRUE FALSE FALSE 677.680364 613.6296597 914.4595425 844.879587 820.5573069 792.0339156 586.1571551 1223.365532 668.8130455 958.799281 0.706801076 0.639998039 0.953754931 0.881185044 0.855817608 0.826068533 0.611345009 1.27593497 0.697552719 1 9.905085017 -4.241234503 24.30838275 0.836395854 1.275935582 0.533479501 0.129738828 2441.387946 2937156.844 0.019968496 1.068840186 5.74E-05 4.241234503 0.439539728 AAFVLPEFAR ddPTM_HeLa_Curcumin_4h_R1 1 AAFVLPEFAR 10 0 K7EL89;P19623 K7EL89 SRM Spermidine synthase 0 0 114.5 0.0040041 624150 550.79 282.45 336.06 282.98 286.69 442.71 403.93 378.97 374.3 406.89 FALSE FALSE TRUE 507.1943903 306.8637194 348.5146792 281.8091037 283.271409 350.8869556 415.2631887 494.5162084 333.2402265 421.0293972 1.204653152 0.728841552 0.827768041 0.669333556 0.672806723 0.833402508 0.986304499 1.174540808 0.791489213 1 8.717777159 -7.260984658 24.99979486 1.096641767 0.833408014 0.065890704 0.178199966 34.10780662 1875197.06 0.028202097 0.033439835 5.48E-08 7.260984658 -0.263233753 AAGEK(ac)AVAGADK ddPTM_HeLa_Curcumin_4h_R1 2 AAGEKAVAGADK 12 1 P50548;P50548-2 P50548 ERF ETS domain-containing transcription factor ERF 0 1 ; AAGEK(1)AVAGADK;AAGEK(1)AVAGADK 162.49 7.25E-06 18102900 7755 7097.1 8425.4 7219.3 5788 7928.5 3902.5 3437.3 7157.7 5911.8 FALSE TRUE FALSE 7141.183567 7710.5417 8737.652736 7189.428449 5718.98188 6284.039727 4011.993647 4485.316947 6372.518218 6117.23461 1.167387557 1.260461988 1.428366459 1.175274271 0.934896607 1.02726806 0.655850871 0.733226242 1.041731865 1 12.57866389 -4.947814916 1.54950656 1.125733109 0.668587126 0.628090721 0.134772878 0.266259342 1.134043292 0.022845407 0.124098489 1.13E-05 4.947814916 -0.457145983 AAGGAAPETPAIS(ph)PSKR ddPTM_HeLa_Curcumin_4h_R1 1 AAGGAAPETPAISPSKR 17 1 H0YNW5;H0YMM5 H0YNW5 DUT 1 0 AAGGAAPETPAIS(0.999)PS(0.001)KR 176.42 9.06E-19 0 2595.3 2203.3 2658 2466 2596.3 2976.8 2436 2330.3 2641.9 2585.3 TRUE FALSE FALSE 2389.879266 2393.743434 2756.507818 2455.796345 2565.340818 2359.378125 2504.347604 3040.797743 2352.09018 2675.138983 0.893366394 0.894810868 1.030416676 0.918007012 0.95895609 0.88196469 0.936156073 1.136687762 0.879240367 1 11.38539813 -4.260053917 24.72195085 0.943761409 1.136687835 0.597124048 0.049539415 59.61352626 1063600.713 0.007160298 0.059840507 5.49E-05 4.260053917 0.192926425 AAGGAPS(ph)PPPPVR ddPTM_HeLa_Curcumin_4h_R1 4 AAGGAPSPPPPVR 13 0 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 0 AAGGAPS(1)PPPPVR;AAGGAPS(1)PPPPVR;AAGGAPS(1)PPPPVR;AAGGAPS(1)PPPPVR ;;; 166.45 0.00018203 226023000 7088.59 6046.01 6220.91 6577.1 7049.52 7638.3 6336.62 6198.29 7069.74 6415.65 TRUE FALSE FALSE 6527.520622 6568.600164 6451.462397 6549.885703 6965.459078 6054.030479 6514.408503 8088.120088 6294.20721 6638.59336 0.983268634 0.989456622 0.971811655 0.986637582 1.049237195 0.911944768 0.981293498 1.218348474 0.948123626 1 12.69666187 -4.260429041 24.97539978 0.987984451 1.218348547 0.813203977 0.034058391 23.35286032 577193.2626 0.004071038 0.033428862 5.49E-05 4.260429041 0.230364096 AAGGAPS(ph)PPPPVRR ddPTM_HeLa_Curcumin_4h_R1 1 AAGGAPSPPPPVRR 14 1 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 0 AAGGAPS(1)PPPPVRR 69.229 0.016029 157280000 5622.1 4536 4707.2 5025.3 5068.4 5591.5 3129.7 2363.8 6367.9 4989 TRUE FALSE FALSE 5177.104853 4928.071628 4881.652973 5004.50664 5007.96264 4431.759871 3217.510959 3084.511738 5669.357302 5162.367379 1.00285479 0.954614669 0.945622931 0.969420863 0.970090323 0.858474329 0.623262686 0.597499463 1.098208803 1 12.3338171 -4.876636352 1.983341638 0.990281696 0.581532744 0.932452538 0.04063379 0.039126133 0.290833612 0.003831942 0.018633929 1.33E-05 4.876636352 -0.408748952 AAGGGAGS(ph)SEDDAQS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 AAGGGAGSSEDDAQSR 16 0 D6REM1;Q9H4A6 D6REM1 GOLPH3 Golgi phosphoprotein 3 2 0 AAGGGAGS(0.832)S(0.173)EDDAQS(0.995)R 120.59 0.0021546 6927500 4345.8 3951.1 4425.6 4293.1 5152.5 5081.3 3818.8 2529.1 4108.3 3637.5 TRUE FALSE FALSE 4001.825344 4292.615478 4589.616629 4275.33629 5091.059803 4027.381102 3925.94525 3300.210947 3657.629768 3763.902854 1.063211645 1.140469253 1.219377016 1.13587849 1.352601276 1.070001341 1.043051695 0.876805559 0.971765189 1 11.87801368 -7.675064634 1.664192662 1.0204348 1.127248279 0.152457804 0.116861108 0.506184379 2.902644778 0.024735869 0.024842305 2.11E-08 7.675064634 0.10681348 AAGGGAGSSEDDAQSR ddPTM_HeLa_Curcumin_4h_R1 2 AAGGGAGSSEDDAQSR 16 0 D6REM1;Q9H4A6 D6REM1 GOLPH3 Golgi phosphoprotein 3 0 0 ; ; 269.81 1.27E-76 1186580 388.69 326.743 309.88 325.64 469.25 429.96 392.23 209.121 398.92 446.69 FALSE FALSE TRUE 357.9247764 354.985209 321.3644254 324.292588 463.6545002 340.7814494 403.2349182 272.8810302 355.159474 462.2124443 0.774372869 0.768013093 0.695274282 0.701609383 1.003119899 0.737283155 0.872401691 0.590380103 0.768390117 1 8.852412292 -9.085811344 0.736192785 1.009591405 0.77234491 0 0.125973467 0.582278019 0.542344074 0.081303795 0.020925633 8.21E-10 9.085811344 -0.237246494 AAGGS(ph)PAVGCTTR ddPTM_HeLa_Curcumin_4h_R1 2 AAGGSPAVGCTTR 13 0 B5MC79;B5MC16;Q7Z624-2;Q7Z624 B5MC79 CAMKMT Calmodulin-lysine N-methyltransferase 1 0 AAGGS(0.998)PAVGCT(0.002)TR;AAGGS(0.996)PAVGCT(0.002)T(0.002)R ; 128.35 0.0017624 12706500 2349.5 1774.95 2116.2 2239.06 2161.17 3407.7 2688.7 1477.6 2241.31 1973.3 TRUE FALSE FALSE 2163.534596 1928.368769 2194.628234 2229.795363 2135.399459 2700.904607 2764.137686 1928.113438 1995.4439 2041.872028 1.059583836 0.944412158 1.074811841 1.092034825 1.045804747 1.322759003 1.353727191 0.944287111 0.97726198 1 10.99567673 -5.354049135 7.269424715 1.0313864 1.221107122 0.353026858 0.110682272 0.192248267 13.13984254 0.014604477 0.032821491 4.43E-06 5.354049135 0.189720722 AAGIGK(ac)DFK ddPTM_HeLa_Curcumin_4h_R1 1 AAGIGKDFK 9 1 Q13523;H0YDJ3 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 0 1 AAGIGK(1)DFK 117.89 0.0014868 1413700 1540.1 1313.4 1457.9 1272.6 1675.4 1815 1547.8 1858.6 1565.7 1180.9 FALSE TRUE FALSE 1418.19946 1426.924444 1511.931056 1267.334318 1655.421949 1438.548541 1591.227102 2425.278584 1393.946627 1221.936187 1.16061663 1.167756924 1.23732407 1.03715262 1.354753191 1.177269776 1.30221784 1.984783338 1.140768759 1 10.25495323 -1.274103993 0.866178551 1.103459207 200 0.855895666 0.099943175 112.510156 0.471764961 0.017012309 43885.55667 0.053198086 1.274103993 198.8965408 AAGISLIVPGKS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 AAGISLIVPGKSPTR 15 1 F2Z357;J3KPC5;P47736;P47736-3;P47736-4 F2Z357 RAP1GAP Rap1 GTPase-activating protein 1 1 0 AAGISLIVPGKS(0.748)PT(0.252)R 103.73 0.0012643 36678000 2118.7 1912.7 1875.6 1869 2079.3 2248.5 1498.6 1133.1 2497.7 2019.6 TRUE FALSE FALSE 1951.002659 2078.025265 1945.111386 1861.266573 2054.505706 1782.135754 1540.646683 1478.576974 2223.708559 2089.78095 0.933591944 0.994374681 0.930772857 0.890651517 0.983120124 0.852785913 0.737228791 0.707527253 1.064086913 1 11.02913601 -4.914067812 1.962020233 0.962632392 0.704858995 0.826251574 0.045620859 0.086503102 0.631137954 0.005419433 0.025193165 1.22E-05 4.914067812 -0.257773397 AAGISLIVPGKSPT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 AAGISLIVPGKSPTR 15 1 F2Z357;J3KPC5;P47736;P47736-3;P47736-4 F2Z357 RAP1GAP Rap1 GTPase-activating protein 1 1 0 AAGISLIVPGKS(0.35)PT(0.65)R 110.32 0.0017984 36181000 3770.1 2965.1 3046.5 3311.9 3472.8 3685.7 2229.1 1913.3 3754.6 3497.6 TRUE FALSE FALSE 3471.692607 3221.390032 3159.40597 3298.196235 3431.389128 2921.244274 2291.642547 2496.656362 3342.729774 3619.14134 0.959258642 0.890097879 0.872971148 0.911320097 0.948122443 0.807165015 0.633200622 0.689847709 0.923625098 1 11.82143174 -3.243229484 0.345265765 0.989680621 2.14E-14 0.760412387 0.055384126 3.543738243 0.173672354 0.016963877 1.692158213 0.000571177 3.243229484 -0.989680621 AAGK(ac)RPAEDDVPR ddPTM_HeLa_Curcumin_4h_R1 1 AAGKRPAEDDVPR 13 2 D6RD44;Q96EI5;Q96EI5-2;A2RQR6 D6RD44 TCEAL4 Transcription elongation factor A protein-like 4 0 1 AAGK(1)RPAEDDVPR 92.781 0.0034997 2401300 2497.7 2491.7 2182.1 1918.9 2133.1 3431.9 1462.4 1767 2715.7 2561.6 FALSE TRUE FALSE 2300.004409 2707.071445 2262.970546 1910.9601 2107.664176 2720.085255 1503.431008 2305.750166 2417.794504 2650.615409 0.867724681 1.021299218 0.853752882 0.720949593 0.795160312 1.026208949 0.567200735 0.869892387 0.912163453 1 11.37211164 -6.541418751 9.630299207 0.941913213 0.795054611 0.284949262 0.115112217 0.267069581 129.2342605 0.017695343 0.025185822 2.87E-07 6.541418751 -0.146858602 AAGMS(ph)SPGAQSHPEELPR ddPTM_HeLa_Curcumin_4h_R1 1 AAGMSSPGAQSHPEELPR 18 0 M0R0P8;Q13459-2;Q13459;M0R300;M0QZY4;M0R2J3 M0R0P8 MYO9B Unconventional myosin-IXb 1 0 AAGMS(0.801)S(0.199)PGAQSHPEELPR 100.95 0.00065247 36713000 1632.4 1903.7 1364.3 1894.3 1546.1 1819.9 1443.4 1345.8 2338.4 2072.7 TRUE FALSE FALSE 1503.193817 2068.247345 1414.862158 1886.461889 1527.663767 1442.432225 1483.897919 1756.128225 2081.88337 2144.726171 0.700879132 0.964340984 0.659693614 0.879581699 0.712288491 0.672548433 0.691882227 0.818812326 0.970698917 1 11.06657775 -9.51741995 0.728140978 1.041512452 0.754604669 0.472059876 0.094028932 0.690061181 0.493814335 0.129910769 0.018005263 3.04E-10 9.51741995 -0.286907783 AAGMSS(ph)PGAQSHPEELPR ddPTM_HeLa_Curcumin_4h_R1 1 AAGMSSPGAQSHPEELPR 18 0 M0R0P8;Q13459-2;Q13459;M0R300;M0QZY4;M0R2J3 M0R0P8 MYO9B Unconventional myosin-IXb 1 0 AAGMS(0.177)S(0.823)PGAQSHPEELPR 161.14 1.45E-05 26331000 2293.6 2695.4 2208.8 2356.8 1617.7 2069.8 1633.5 1925.7 2732.5 2454.2 TRUE FALSE FALSE 2112.05914 2928.378366 2290.660071 2347.048186 1598.409984 1640.500149 1679.331614 2512.837065 2432.751586 2539.483267 0.831688543 1.153139461 0.902018178 0.924222741 0.629423318 0.645997621 0.66128871 0.989507235 0.957971103 1 11.31031925 -5.804363948 10.78001197 0.936822854 0.720490471 0.444584611 0.123842323 0.408074784 100.8114936 0.01884316 0.034231633 1.57E-06 5.804363948 -0.216332384 KPDGVKES(ph)TESSNTTIEDEDVK ddPTM_HeLa_Curcumin_4h_R1 3 KPDGVKESTESSNTTIEDEDVK 22 2 H0Y9J2;D6R938;Q13557-8;Q13557-12;Q13557 H0Y9J2 CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 1 0 KPDGVKES(0.366)T(0.366)ES(0.144)S(0.052)NT(0.052)T(0.02)IEDEDVK;KPDGVKES(0.771)T(0.21)ES(0.016)S(0.001)NT(0.001)TIEDEDVK;KPDGVKES(0.741)T(0.237)ES(0.016)S(0.005)NT(0.001)TIEDEDVK ;; 85.224 0.00047036 17565400 3060 2048.28 2672.65 2226.4 2284.87 9777.2 12937.8 8066.7 2362.99 1813.15 TRUE FALSE FALSE 2817.797771 2225.324196 2771.70076 2217.187747 2257.624418 7749.298508 13300.79985 10526.1997 2103.775909 1876.156828 1.501898844 1.186107773 1.477328931 1.181771009 1.203323936 4.130410845 7.089385947 5.610511627 1.121321991 1 10.87356471 -5.066554292 2.88534292 1.24656588 6.333215554 0.963445634 0.404265914 0.030360225 0.492271675 0.054947163 0.173411636 8.58E-06 5.066554292 5.086649674 up AAGSGELGVTMK ddPTM_HeLa_Curcumin_4h_R1 2 AAGSGELGVTMK 12 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 108.31 0.0039568 7188700 4074.2 3134.9 3785.2 3447.8 3912.2 5136.2 3644.9 3662.2 3898.3 3831.6 FALSE FALSE TRUE 3751.722771 3405.866787 3925.482842 3433.533917 3865.54957 4070.894223 3747.166084 4778.787921 3470.666243 3964.747815 0.946270216 0.859037433 0.990096477 0.866015716 0.974979936 1.02677255 0.945120915 1.205319517 0.875381337 1 11.95301339 -4.258961979 24.76994399 0.962263916 1.205319615 0.629306552 0.058770242 93.87261784 938506.3633 0.007301217 0.065545444 5.51E-05 4.258961979 0.243055699 AAGSPS(ph)SSDQDEKLPGQDESTAGTSEQNDILK ddPTM_HeLa_Curcumin_4h_R1 1 AAGSPSSSDQDEKLPGQDESTAGTSEQNDILK 32 1 E7EPN9;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 1 0 AAGS(0.12)PS(0.267)S(0.267)S(0.267)DQDEKLPGQDES(0.062)T(0.016)AGTSEQNDILK 66.432 2.65E-05 20192000 4534.5 3401.4 4465.7 4293.3 4640.2 5749.6 4220.8 2486.8 5184.5 4247.4 TRUE FALSE FALSE 4175.58954 3695.40186 4631.20277 4275.535462 4584.868646 4557.068149 4339.224288 3245.013872 4615.773321 4394.996834 0.95007794 0.840820141 1.053744279 0.972818781 1.043201809 1.036876321 0.987309992 0.73834271 1.050233594 1 12.10164641 -4.26050312 24.57480671 0.980886306 0.738342612 0.598868772 0.061785761 31.85222355 835884.1438 0.007976 0.064653462 5.49E-05 4.26050312 -0.242543694 TYSLGSALRPST(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 TYSLGSALRPSTSR 14 1 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 0 TYSLGS(0.178)ALRPS(0.159)T(0.597)S(0.067)R 143.56 0.0064978 193840000 3288.4 2596.8 2766.8 2951.9 3181.4 6615.1 8982.6 4723.4 2590.2 2572.1 TRUE FALSE FALSE 3028.11967 2821.255821 2869.340042 2939.68582 3143.463883 5243.053692 9234.627581 6163.542916 2306.06154 2661.480284 1.137757694 1.060032583 1.078099304 1.104530377 1.181096062 1.96997653 3.469733606 2.315832642 0.866458247 1 11.37801316 -5.05296171 3.053454247 1.076511677 2.890533347 0.869712837 0.283645909 0.050759996 0.932451634 0.034058817 0.106468209 8.85E-06 5.05296171 1.81402167 up AMS(ph)TTSISS(ph)PQPGK ddPTM_HeLa_Curcumin_4h_R1 1 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 2 0 AMS(0.989)T(0.011)T(0.004)S(0.013)IS(0.037)S(0.946)PQPGK 91.307 0.010978 6445600 2399.7 1461 1595.8 2008.4 1999.7 4130.3 5036 3221.8 2308.6 1493.4 TRUE FALSE FALSE 2209.761213 1587.28233 1654.941752 2000.089773 1975.854884 3273.629222 5177.296606 4204.111989 2055.352356 1545.295539 1.429992618 1.027170719 1.07095485 1.294308903 1.27862589 2.118448633 3.350360158 2.720587669 1.330070724 1 10.59366707 -5.04606894 2.64748658 1.192069941 3.03799125 0.926599336 0.20662008 0.051251757 0.703562965 0.03160773 0.105366299 8.99E-06 5.04606894 1.845921309 up RGES(ph)LDNLDS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 RGESLDNLDSPR 12 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 2 0 RGES(1)LDNLDS(1)PR;RGES(1)LDNLDS(1)PR ; 108.14 0.0094123 53349000 3719.1 2917.1 3130.3 3398.1 3723.3 7167.6 7482 6050.9 3522.1 2650.9 TRUE FALSE FALSE 3424.729311 3169.241126 3246.311672 3384.039563 3678.902079 5680.958964 7691.924783 7895.791555 3135.734442 2743.018578 1.248525744 1.155384492 1.183481475 1.233691813 1.341187446 2.071061061 2.804182533 2.878504586 1.143169232 1 11.42154868 -5.033005857 1.594147517 1.132371837 2.956035875 0.989277106 0.070008275 0.039765236 0.184075515 0.015073464 0.070674175 9.27E-06 5.033005857 1.823664038 up EIS(ph)SS(ph)PTSKNR ddPTM_HeLa_Curcumin_4h_R1 1 EISSSPTSKNR 11 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 EIS(0.704)S(0.3)S(0.893)PT(0.097)S(0.006)KNR 124.6 0.00098278 0 5567.3 3066.7 2515.9 3292.7 1670.8 4219.8 2413.1 2661.2 9391.5 7405.4 TRUE FALSE FALSE 5126.64233 3331.771883 2609.141467 3279.07568 1650.876801 3344.565913 2480.805091 3472.587629 8361.275946 7662.737099 0.669035394 0.4348018 0.340497323 0.427924857 0.215442182 0.436471442 0.323749211 0.45317849 1.091160487 1 12.90364409 -7.818290759 0.653544828 0.961881909 0.342482757 0.894533601 0.089870537 0.12802554 0.12362401 0.029880543 0.02343379 1.52E-08 7.818290759 -0.619399152 GS(ph)KSPAKVSDGGSSSTDFK ddPTM_HeLa_Curcumin_4h_R1 1 GSKSPAKVSDGGSSSTDFK 19 2 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659;A0A087X146 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 GS(0.494)KS(0.494)PAKVS(0.011)DGGS(0.001)SSTDFK 42.068 0.019494 54290000 3951.5 2465.8 1910.2 2795.7 1340.1 2911.7 1510.4 1753 5705.2 4565.7 TRUE FALSE FALSE 3638.734605 2678.932765 1980.993692 2784.132134 1324.120183 2307.780598 1552.777759 2287.48163 5079.353834 4724.357735 0.770207256 0.567046975 0.419314921 0.589314419 0.280275173 0.488485574 0.32867489 0.484188912 1.075141663 1 12.2059025 -7.426970033 0.644880497 0.966389672 0.393291608 0.865989414 0.093350129 0.142445151 0.130570222 0.025628375 0.026989388 3.74E-08 7.426970033 -0.573098064 IEVEK(ac)PFAIAKE ddPTM_HeLa_Curcumin_4h_R1 1 IEVEKPFAIAKE 12 2 P23284 P23284 PPIB Peptidyl-prolyl cis-trans isomerase B 0 1 IEVEK(1)PFAIAKE 126.12 0.0028838 1100300 836.7 689.74 678.12 646.76 1296.3 2325.1 1264.2 1315.5 1468.5 753.65 FALSE TRUE FALSE 770.4743121 749.3580522 703.2517237 644.0838785 1280.842469 1842.848051 1299.67005 1716.589894 1307.409224 779.8392814 0.987991155 0.960913447 0.901790588 0.825918742 1.642444154 2.363112624 1.666587053 2.201209833 1.676511116 1 9.607033017 -5.596040549 4.10290641 0.97443929 2.035272003 0.72013302 0.283461915 0.044309663 1.460332706 0.023005258 0.048107658 2.53E-06 5.596040549 1.060832713 AAIDWFDGK ddPTM_HeLa_Curcumin_4h_R1 1 AAIDWFDGK 9 0 Q92804-2;Q92804;A0A075B7D9;H3BPE7;P35637-2;P35637 Q92804-2;H3BPE7 TAF15;FUS TATA-binding protein-associated factor 2N;RNA-binding protein FUS 0 0 130.75 0.00057954 1628700 1957 1887.8 1786.5 1899.7 1911.3 1936 1697 1934.4 1567.8 893.79 FALSE FALSE TRUE 1802.101385 2050.97302 1852.709262 1891.839545 1888.508996 1534.451777 1744.613253 2524.189655 1395.816262 924.849136 1.948535512 2.217629817 2.003255655 2.045565564 2.041964384 1.659137385 1.886376042 2.72929882 1.509236705 1 9.853074238 -9.001725651 0.590440884 0.900560231 2.071772997 0.510947631 0.301902934 0.431105165 0.249170919 0.264133073 0.062543923 9.96E-10 9.001725651 1.171212766 AAIPPPVYEEQDRPRS(ph)PTGPSNSFLANMGGTVAHK ddPTM_HeLa_Curcumin_4h_R1 2 AAIPPPVYEEQDRPRSPTGPSNSFLANMGGTVAHK 35 2 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 0 AAIPPPVY(0.048)EEQDRPRS(0.387)PT(0.126)GPS(0.387)NS(0.053)FLANMGGTVAHK;AAIPPPVY(0.147)EEQDRPRS(0.513)PT(0.136)GPS(0.102)NS(0.102)FLANMGGT(0.001)VAHK ; 50.581 0.0020531 311390000 6158.6 4518.8 4729 5202.3 5457.4 7687.9 5657.6 5181 6776.5 5134.3 TRUE FALSE FALSE 5671.140311 4909.384937 4904.2609 5180.774261 5392.324069 6093.34288 5816.337029 6760.66305 6033.134904 5312.716543 1.067465254 0.924081851 0.923117366 0.975164818 1.014984335 1.146935439 1.094795286 1.272543527 1.135602635 1 12.37523403 -4.259231444 0.97716021 1.011544246 1.389775419 0.584605536 0.06745646 1.023780066 0.737978827 0.009753008 0.407500961 5.51E-05 4.259231444 0.378231173 AAIPPPVYEEQDRPRSPTGPSNS(ph)FLANMGGTVAHK ddPTM_HeLa_Curcumin_4h_R1 1 AAIPPPVYEEQDRPRSPTGPSNSFLANMGGTVAHK 35 2 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 0 AAIPPPVY(0.018)EEQDRPRS(0.046)PT(0.046)GPS(0.169)NS(0.659)FLANMGGT(0.062)VAHK 46.048 0.0059382 47755000 2688.9 1822.1 2415.1 2296 2419.7 2445.9 1606 929.8 2517.9 1762.5 TRUE FALSE FALSE 2476.070728 1979.594205 2504.605731 2286.49976 2390.846658 1938.592769 1651.060038 1213.29174 2241.692669 1823.746744 1.357683426 1.085454552 1.373329789 1.253737542 1.310953215 1.062972573 0.905312124 0.665274246 1.22916884 1 10.83268969 -4.590457645 1.803476698 1.196096861 0.645880308 0.711650602 0.114976232 0.275266475 1.394197011 0.021959059 0.206094038 2.57E-05 4.590457645 -0.550216553 AAK(ac)APPK ddPTM_HeLa_Curcumin_4h_R1 1 AAKAPPK 7 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2;S4R349;S4R3C2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 1 AAK(1)APPK 107.66 0.015162 2209300 1930 1442.5 1855.7 1323.6 1941.9 2218 1770.3 1028.8 1713.1 1735.1 FALSE TRUE FALSE 1777.238463 1567.183272 1924.473874 1318.123294 1918.744111 1757.961798 1819.969853 1342.476384 1525.177216 1795.394596 0.989887386 0.872890715 1.071894657 0.734169133 1.06870329 0.979150657 1.013687942 0.747733332 0.849494155 1 10.81008524 -4.256163213 24.51413818 0.979437844 0.747733203 0.230297075 0.103255086 339.2833661 1576312.313 0.011661269 0.131376226 5.54E-05 4.256163213 -0.231704641 ELPPLS(ph)PSLSRR ddPTM_HeLa_Curcumin_4h_R1 2 ELPPLSPSLSRR 12 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 0 ELPPLS(0.998)PS(0.001)LS(0.001)RR;ELPPLS(0.994)PS(0.003)LS(0.003)RR ; 115.06 0.0019094 10989400 5218.9 3701.8 3018.1 4350.2 2435.5 5454.7 2705.9 1746.67 7202.9 5925.6 TRUE FALSE FALSE 4805.818558 4021.767097 3129.953441 4332.200025 2406.458253 4323.333733 2781.820271 2279.221642 6412.759891 6131.514159 0.783789849 0.655917444 0.510469903 0.706546526 0.392473733 0.705100505 0.45369222 0.371722479 1.045868887 1 12.58202767 -7.381487355 0.271197617 1.083402252 0.373717972 0.79115461 0.102551275 0.529391215 0.140940088 0.135423724 0.137221374 4.15E-08 7.381487355 -0.70968428 AAKLS(ph)EGSQPAEEEEDQETPSR ddPTM_HeLa_Curcumin_4h_R1 4 AAKLSEGSQPAEEEEDQETPSR 22 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 AAKLS(0.977)EGS(0.023)QPAEEEEDQETPSR;AAKLS(0.758)EGS(0.242)QPAEEEEDQETPSR;AAKLS(0.764)EGS(0.236)QPAEEEEDQETPSR;AAKLS(0.531)EGS(0.469)QPAEEEEDQETPSR ;;; 110.61 1.09E-05 168745000 10208.8 8395.8 8967.7 8468 8271.9 9307.9 6172.1 4269.58 11433.6 9066.5 TRUE FALSE FALSE 9400.762708 9121.495541 9300.050851 8432.96166 8173.262995 7377.336618 6345.272515 5571.355287 10179.36269 9381.5602 1.002046835 0.972279167 0.991311749 0.89888691 0.87120509 0.786365643 0.676355785 0.593862339 1.085039425 1 13.19561215 -4.760915824 0.625440394 1.003232458 0.456093525 0.96195194 0.029206232 0.113535252 0.043498765 0.002327523 0.03933268 1.73E-05 4.760915824 -0.547138933 AAKLSEGS(ph)QPAEEEEDQETPSR ddPTM_HeLa_Curcumin_4h_R1 1 AAKLSEGSQPAEEEEDQETPSR 22 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 AAKLS(0.253)EGS(0.744)QPAEEEEDQET(0.002)PS(0.001)R 45.941 0.01942 7023900 3304.3 2542.3 2457.9 3003.6 2633.4 3377.2 2339 2088.5 3265.6 3114.2 TRUE FALSE FALSE 3042.761168 2762.045084 2548.991936 2991.171899 2601.998425 2676.730651 2404.626045 2725.274036 2907.37185 3222.418218 0.944247755 0.857134269 0.791018348 0.928238266 0.807467637 0.830658986 0.746217866 0.845723258 0.902232936 1 11.65392803 -7.264686332 0.570549139 0.996266601 0.804487017 0.468246492 0.053781685 0.267947269 0.197342217 0.014843212 0.017566129 5.44E-08 7.264686332 -0.191779585 AAKPGPAEAPS(ph)PT(ph)ASPSGDASPPATAPYDPR ddPTM_HeLa_Curcumin_4h_R1 2 AAKPGPAEAPSPTASPSGDASPPATAPYDPR 31 1 M0QY97;Q9UPT8 M0QY97 ZC3H4 Zinc finger CCCH domain-containing protein 4 2 0 AAKPGPAEAPS(0.961)PT(0.621)AS(0.194)PS(0.162)GDAS(0.058)PPAT(0.004)APY(0.001)DPR;AAKPGPAEAPS(0.998)PT(0.978)AS(0.022)PS(0.002)GDAS(0.001)PPATAPYDPR ; 80.733 5.45E-06 91060000 2854.5 1883.4 2347.03 2676.5 2265.81 2780.5 2029.3 3219.7 3411.2 2405.9 TRUE FALSE FALSE 2628.563313 2046.192704 2434.012996 2665.425352 2238.791696 2203.792957 2086.236696 4201.371708 3036.999894 2489.504846 1.055857882 0.821927584 0.977709684 1.070664858 0.899291961 0.885233447 0.838012708 1.687633473 1.219921262 1 11.28164311 -4.254013032 24.97044497 0.985646501 1.687633811 0.773912326 0.115520988 264.2941235 888644.0568 0.013323493 0.185284589 5.57E-05 4.254013032 0.70198731 AAKPGPAEAPS(ph)PTASPS(ph)GDASPPATAPYDPR ddPTM_HeLa_Curcumin_4h_R1 1 AAKPGPAEAPSPTASPSGDASPPATAPYDPR 31 1 M0QY97;Q9UPT8 M0QY97 ZC3H4 Zinc finger CCCH domain-containing protein 4 2 0 AAKPGPAEAPS(0.655)PT(0.348)AS(0.175)PS(0.429)GDAS(0.353)PPAT(0.038)APY(0.002)DPR 60.64 0.0015999 0 396.47 363.63 252.94 358.39 446.98 614.08 178.88 546.6 547.71 340.81 TRUE FALSE FALSE 365.0889811 395.0605569 262.3141789 356.9070771 441.6500554 486.7128859 183.8988914 713.2558238 487.6275833 352.6531221 1.035263714 1.120252543 0.743830587 1.012062718 1.252363946 1.380146255 0.521472461 2.022542206 1.382740015 1 8.462106002 -4.242150054 24.62140206 1.020563147 2.02254332 0.564706946 0.255054001 1653.847756 2110976.412 0.028455243 1.396201548 5.73E-05 4.242150054 1.001980174 AAKPGPAEAPSPT(ph)AS(ph)PSGDASPPATAPYDPR ddPTM_HeLa_Curcumin_4h_R1 1 AAKPGPAEAPSPTASPSGDASPPATAPYDPR 31 1 M0QY97;Q9UPT8 M0QY97 ZC3H4 Zinc finger CCCH domain-containing protein 4 2 0 AAKPGPAEAPS(0.181)PT(0.563)AS(0.722)PS(0.259)GDAS(0.192)PPAT(0.071)APY(0.012)DPR 71.927 0.00012549 20188000 1227.5 1323.5 1256.8 1366.8 1113.3 1720.7 1477.5 1709.1 1510.1 1413.2 TRUE FALSE FALSE 1130.34208 1437.897443 1303.378114 1361.144544 1100.024625 1363.807424 1518.954674 2230.196722 1344.445808 1462.308595 0.772984638 0.983306429 0.891315361 0.930818945 0.752252041 0.932639956 1.038737431 1.525120436 0.919399512 1 10.51403208 -4.223168228 2.072062034 0.891469461 1.743983198 0.861142003 0.07560533 0.25613692 1.096257126 0.013396471 0.422076216 5.98E-05 4.223168228 0.852513737 AAKPGPAEAPSPT(ph)ASPSGDASPPATAPYDPR ddPTM_HeLa_Curcumin_4h_R1 1 AAKPGPAEAPSPTASPSGDASPPATAPYDPR 31 1 M0QY97;Q9UPT8 M0QY97 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 0 AAKPGPAEAPS(0.072)PT(0.653)AS(0.259)PS(0.005)GDAS(0.009)PPAT(0.001)APYDPR 87.868 8.36E-07 63739000 2654.6 2392.1 2316.7 2662.2 2725.4 3180.4 2136.8 2169.3 2632.7 2293.8 TRUE FALSE FALSE 2444.485609 2598.862465 2402.55894 2651.184522 2692.901385 2520.74919 2196.752857 2830.709584 2343.899397 2373.509379 1.029903497 1.0949451 1.012239076 1.116989275 1.134565302 1.062034644 0.925529461 1.192626247 0.987524809 1 11.21280604 -7.608030767 0.983789767 1.007009527 1.073985351 0.183723483 0.068542061 0.64726709 1.29552767 0.015829793 0.01567378 2.47E-08 7.608030767 0.066975824 AAKPGPAEAPSPTASPSGDAS(ph)PPATAPYDPR ddPTM_HeLa_Curcumin_4h_R1 2 AAKPGPAEAPSPTASPSGDASPPATAPYDPR 31 1 M0QY97;Q9UPT8 M0QY97 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 0 AAKPGPAEAPSPTASPS(0.007)GDAS(0.491)PPAT(0.491)APY(0.011)DPR;AAKPGPAEAPSPTASPS(0.007)GDAS(0.966)PPAT(0.027)APYDPR ; 115.5 2.06E-13 80504000 5254 3728.4 4105.7 3955.2 4121.8 5384.8 4467.7 5975.7 4822.1 4614.3 TRUE FALSE FALSE 4838.140356 4050.666283 4257.860854 3938.83443 4072.650227 4267.931781 4593.051638 7797.663421 4293.127694 4774.646582 1.01329811 0.848369866 0.891764611 0.82494785 0.852974175 0.893873862 0.96196683 1.633139393 0.899150884 1 12.22117823 -4.261552594 8.074689736 0.956038959 1.638369167 0.889991667 0.074728533 0.027208813 22.43354148 0.012762565 0.100886208 5.48E-05 4.261552594 0.682330208 AAKPTTTPEVK ddPTM_HeLa_Curcumin_4h_R1 1 AAKPTTTPEVK 11 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 0 95.618 0.0008665 0 1692.2 1236 1321.1 1528.6 1450.7 2309.9 1449.5 1411.5 1722.9 1426.7 FALSE FALSE TRUE 1558.260584 1342.834332 1370.061128 1522.275058 1433.40135 1830.800702 1490.169069 1841.859852 1533.90218 1476.277719 1.055533498 0.909608209 0.928051078 1.031157647 0.970956434 1.240146538 1.009409713 1.247637778 1.039033619 1 10.52774843 -5.275155595 24.99378435 1.007456537 1.150099184 0.512989531 0.076520238 523.0315212 953071.2529 0.010520023 0.023637513 5.31E-06 5.275155595 0.142642647 AALAPAKES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 AALAPAKESPR 11 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;H0YAB7;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 AALAPAKES(1)PR;AALAPAKES(1)PR ; 105.65 0.0036359 5763700000 15002.4 12972.3 13088.7 13959.1 14402.8 17792.8 16089.5 7905.5 15290.5 13519.2 TRUE FALSE FALSE 13814.94421 14093.56781 13573.77874 13901.34094 14231.05602 14102.37271 16540.92807 10315.85056 13613.1704 13988.99119 0.987558289 1.007475637 0.970318628 0.993734341 1.017303951 1.008105053 1.182424654 0.737426339 0.973134532 1 13.77200431 -4.233330747 24.60538654 1.005184558 0.737425852 0.666931279 0.058554442 3850.841193 3370838.196 0.007397739 0.986661411 5.84E-05 4.233330747 -0.267758705 AALDGGVASAAS(ph)PESKPSPGTK ddPTM_HeLa_Curcumin_4h_R1 1 AALDGGVASAASPESKPSPGTK 22 1 A0A494C1M5;A0A0J9YWL0;Q9Y4K1 A0A494C1M5 AIM1 Absent in melanoma 1 protein 1 0 AALDGGVAS(0.01)AAS(0.956)PES(0.034)KPSPGTK 99.859 5.16E-05 45878000 1489.9 1195.6 967.07 1546.3 1020.9 1233.5 1112.2 424.02 1437.7 1264.5 TRUE FALSE FALSE 1371.972843 1298.942337 1002.910465 1539.90182 1008.726434 977.6581956 1143.405339 553.3017461 1279.987907 1308.441281 1.048555149 0.992740259 0.766492528 1.176897919 0.770937488 0.747193023 0.873868285 0.422870903 0.978253992 1 10.35363347 -3.893587641 0.531680277 1.017591859 1.28E-14 0.586641329 0.129338399 2.605688545 0.377833981 0.023302868 1.790152633 0.000127765 3.893587641 -1.017591859 AALEDS(ph)SGSSELQEIMR ddPTM_HeLa_Curcumin_4h_R1 1 AALEDSSGSSELQEIMR 17 0 A0A2R8Y4W2;A0A2R8YE63;Q12929-2;Q12929 A0A2R8Y4W2 EPS8 Epidermal growth factor receptor kinase substrate 8 1 0 AALEDS(0.89)S(0.073)GS(0.018)S(0.018)ELQEIMR 98.552 0.0024551 2639300 1299.1 1060.2 882.23 883.67 1237.5 1287.7 952.21 564.9 1162.3 912.41 TRUE FALSE FALSE 1196.274864 1151.838964 914.9262199 880.0136077 1222.743621 1020.616505 978.9264499 737.1354095 1034.798598 944.1161796 1.26708438 1.220018244 0.969082238 0.932103089 1.295119867 1.081028508 1.036870749 0.780767691 1.096050063 1 9.882820593 -4.234187566 2.029920794 1.119988516 0.668059898 0.410672331 0.116836245 0.688231028 2.856186368 0.01943652 0.586835704 5.83E-05 4.234187566 -0.451928618 AALGLQDS(ph)DDEDAAVDIDEQIESMFNSK ddPTM_HeLa_Curcumin_4h_R1 1 AALGLQDSDDEDAAVDIDEQIESMFNSK 28 0 Q7L014;A0A0C4DG89 Q7L014 DDX46 Probable ATP-dependent RNA helicase DDX46 1 0 AALGLQDS(0.993)DDEDAAVDIDEQIES(0.006)MFNS(0.001)K 78.429 8.64E-06 7475500 1727.9 1539.7 1568.9 1644.6 1525.5 1577.9 1335.6 1194.3 1726 1443 TRUE FALSE FALSE 1591.134892 1672.784807 1627.044814 1637.795081 1507.309409 1250.625753 1373.073341 1558.436572 1536.662118 1493.144143 1.06562712 1.12031033 1.089676989 1.096876741 1.009486871 0.837578716 0.919585258 1.043728149 1.029145194 1 10.54413773 -5.509960197 23.71050658 1.04836463 0.930777247 0.498430298 0.058148061 227.8090397 418116.1465 0.009078322 0.019428703 3.09E-06 5.509960197 -0.117587384 T(ph)TSPPEVSGYSYEKTER ddPTM_HeLa_Curcumin_4h_R1 1 TTSPPEVSGYSYEKTER 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(0.728)T(0.136)S(0.136)PPEVSGYSYEKTER 167.92 0.00083295 7792000 1957.3 1334.8 695.46 1434.3 331.91 1342.1 782.4 850.26 3330.7 2231.6 TRUE FALSE FALSE 1802.37764 1450.174164 721.2343594 1428.365247 327.95219 1063.733331 804.3520383 1109.50036 2965.330543 2309.147934 0.78053797 0.628012672 0.312337875 0.618568099 0.142023032 0.460660539 0.348332832 0.480480416 1.284166553 1 11.17314489 -7.297375926 0.82932078 0.947360643 0.371258957 0.740856075 0.165035976 0.163606359 0.229312872 0.029013444 0.033809822 5.04E-08 7.297375926 -0.576101686 AALKEWNGVVSES(ph)DSPVK ddPTM_HeLa_Curcumin_4h_R1 1 AALKEWNGVVSESDSPVK 18 1 M0R0Q7;P18858-2;P18858;B4E135;M0QY71;M0R1G7;F5GZ28 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 AALKEWNGVVS(0.025)ES(0.628)DS(0.348)PVK 115.02 0.00021095 30517000 5020.8 3160.2 3406.2 3474.8 3735.5 4931.7 4640.2 2364.7 4120.7 3422.1 TRUE FALSE FALSE 4623.398382 3433.353606 3532.436768 3460.422198 3690.956602 3908.809828 4770.391524 3085.686144 3668.669519 3541.01772 1.305669372 0.96959515 0.997576699 0.977239447 1.042343443 1.103866215 1.347180924 0.871412229 1.036049466 1 11.78994835 -7.21756456 24.99941015 1.144344083 1.053686526 0.033415151 0.140236307 1030.874463 587382.4252 0.026475356 0.032425501 6.06E-08 7.21756456 -0.090657557 AALKEWNGVVSESDS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 1 AALKEWNGVVSESDSPVK 18 1 M0R0Q7;P18858-2;P18858;B4E135;M0QY71;M0R1G7;F5GZ28 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 AALKEWNGVVSES(0.035)DS(0.964)PVK 106.23 0.00042138 27486000 2017.4 1380.6 1994.2 1905.8 1922.7 2671.5 2038.1 1219 2201.8 1759.2 TRUE FALSE FALSE 1857.720661 1499.932912 2068.106806 1897.914305 1899.773058 2117.400786 2095.283601 1590.667488 1960.268049 1820.332069 1.020539435 0.823988621 1.136115131 1.042619826 1.043640933 1.163194794 1.151044711 0.87383369 1.076873875 1 10.82998594 AALLAQYADVTDEEDEADEKDDS(ph)GATTMNIGSDK ddPTM_HeLa_Curcumin_4h_R1 1 AALLAQYADVTDEEDEADEKDDSGATTMNIGSDK 34 1 Q96MW1 Q96MW1 CCDC43 Coiled-coil domain-containing protein 43 1 0 AALLAQY(0.001)ADVT(0.057)DEEDEADEKDDS(0.31)GAT(0.31)T(0.31)MNIGS(0.011)DK 47.241 0.0049684 11824000 3772.4 3220.4 3265.1 3607.2 3769.6 4121.2 3515.3 4555.7 4044.4 3692.3 TRUE FALSE FALSE 3473.810559 3498.757026 3386.107478 3592.274362 3724.649982 3266.416665 3613.929857 5944.711958 3600.739439 3820.60715 0.909229979 0.91575943 0.886274706 0.940236518 0.974884314 0.854947011 0.945904594 1.555960015 0.942452154 1 11.89958621 -4.261574345 8.489773519 0.941412396 1.559654705 0.954475367 0.040946563 0.015124611 16.89405142 0.006820923 0.053515551 5.48E-05 4.261574345 0.618242309 AALLAQYADVTDEEDEADEKDDSGATT(ph)MNIGSDK ddPTM_HeLa_Curcumin_4h_R1 1 AALLAQYADVTDEEDEADEKDDSGATTMNIGSDK 34 1 Q96MW1 Q96MW1 CCDC43 Coiled-coil domain-containing protein 43 1 0 AALLAQY(0.005)ADVT(0.093)DEEDEADEKDDS(0.059)GAT(0.391)T(0.437)MNIGS(0.015)DK 48.204 0.0067056 63312000 9580.8 7483.5 8298.5 8326.8 7946.4 10037 8180.2 8119.8 8846.8 7477.8 TRUE FALSE FALSE 8822.46957 8130.340394 8606.04971 8292.345908 7851.64437 7955.21306 8409.714396 10595.48964 7876.328174 7737.652993 1.140199693 1.050750195 1.11222999 1.071687489 1.014732035 1.028117062 1.086855976 1.369341537 1.017922124 1 12.91768032 -1 0.012785598 1.74E-10 2.389873012 0.237035965 0.089809089 9973.367931 9.952672022 770.5561514 1120.883508 0.1 1 2.389873012 AALLELWELRR ddPTM_HeLa_Curcumin_4h_R1 2 AALLELWELRR 11 1 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 ; ; 162.36 2.49E-09 5087700 2715.1 2073.89 2639.1 1915.3 2505.3 5802 3525.7 3733.8 2259.79 2354.9 FALSE FALSE TRUE 2500.19697 2253.147811 2736.907368 1907.374996 2475.425934 4598.599798 3624.621653 4872.218432 2011.896691 2436.7326 1.026044864 0.924659444 1.123187406 0.782759256 1.015879188 1.887199194 1.487492577 1.999488344 0.825653455 1 11.25073223 -5.268178767 24.78792256 0.996901321 1.761003304 0.855237326 0.156581446 105.448514 387847.4359 0.018419152 0.042083662 5.39E-06 5.268178767 0.764101982 AALPSLTNPPSLS(ph)PIR ddPTM_HeLa_Curcumin_4h_R1 2 AALPSLTNPPSLSPIR 16 0 P42858 P42858 HTT Huntingtin 1 0 AALPSLT(0.002)NPPS(0.087)LS(0.911)PIR;AALPSLTNPPS(0.026)LS(0.974)PIR ; 174.4 5.46E-05 46993000 2886.74 2568.4 2635.05 3042.6 2591.75 3449.5 2692.34 962.99 2951.9 2828.7 TRUE FALSE FALSE 2658.251483 2790.401051 2732.707271 3030.010527 2560.845074 2734.034816 2767.879814 1256.601218 2628.083955 2926.997114 0.908183841 0.953332355 0.933621443 1.035194231 0.874905227 0.934074995 0.94563804 0.429314129 0.897877194 1 11.51520561 -4.261317435 7.188483788 0.952046128 0.422395883 0.91949939 0.045482189 0.020395356 8.694864299 0.006414781 0.052088445 5.48E-05 4.261317435 -0.529650245 AALPSLTNPPSLS(ph)PIRR ddPTM_HeLa_Curcumin_4h_R1 1 AALPSLTNPPSLSPIRR 17 1 P42858 P42858 HTT Huntingtin 1 0 AALPSLTNPPS(0.059)LS(0.941)PIRR 74.657 0.0067496 10152000 1981.3 1968.9 2022 1955.4 2043.9 2430.6 1968 984.18 2171.3 2147.2 TRUE FALSE FALSE 1824.478014 2139.082943 2096.937099 1947.309073 2019.527827 1926.466161 2023.216783 1284.251951 1933.113822 2221.81504 0.82116557 0.962763733 0.943794628 0.876449676 0.908954072 0.867068647 0.910614406 0.57801929 0.870060643 1 11.11752301 -4.261251915 8.122980173 0.912566812 0.575492077 0.797061725 0.049687314 0.04018038 34.01104796 0.009239581 0.073389346 5.48E-05 4.261251915 -0.337074735 AALQELLSK ddPTM_HeLa_Curcumin_4h_R1 2 AALQELLSK 9 0 P62851 P62851 RPS25 40S ribosomal protein S25 0 0 ; ; 153.05 6.77E-08 7210700 2482.82 1901.8 2452.68 2408.94 2335.59 2458.88 2410.84 1980.89 2468.5 1878.33 FALSE FALSE TRUE 2286.302177 2066.183118 2543.578478 2398.972445 2307.739615 1948.880571 2478.481682 2584.854242 2197.711726 1943.601828 1.176322303 1.063069137 1.308693191 1.234292132 1.18735205 1.002715959 1.275200325 1.32992993 1.130741747 1 10.92451698 -13.52287874 0.161933434 0.213898097 1.254123266 0.190295083 0.102678938 47.26522341 0.508600437 11.69338247 0.178761851 3.00E-14 13.52287874 1.040225169 AALQTAPES(ph)ADDSPSQLSK ddPTM_HeLa_Curcumin_4h_R1 1 AALQTAPESADDSPSQLSK 19 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 0 AALQTAPES(0.997)ADDS(0.003)PSQLSK 225.86 8.05E-25 9099500 6638.6 5647.2 5706.9 6845.2 6221.4 7606.5 5959.5 3253.6 6878.2 5959.4 TRUE FALSE FALSE 6113.147805 6135.318805 5918.402734 6816.876376 6147.213868 6028.826157 6126.707531 4245.607662 6123.678668 6166.488706 0.991349874 0.994945275 0.959768681 1.105471315 0.99687426 0.977675699 0.993548812 0.688496787 0.993057631 1 12.59023352 -4.260941082 6.281260119 0.999639697 0.681342522 0.86789406 0.036626351 0.030096129 6.432606703 0.0047599 0.040501341 5.48E-05 4.260941082 -0.318297175 AALQTAPESADDS(ph)PSQLSK ddPTM_HeLa_Curcumin_4h_R1 1 AALQTAPESADDSPSQLSK 19 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 0 AALQTAPES(0.022)ADDS(0.934)PS(0.042)QLS(0.002)K 199.99 3.35E-38 0 1459.9 1335.2 1150.4 1203.3 1195.6 1859.6 1562.6 700.13 1332.3 1486 TRUE FALSE FALSE 1344.347375 1450.608738 1193.034836 1198.321063 1181.343251 1473.897998 1606.44235 913.596414 1186.150023 1537.638389 0.874293582 0.943400443 0.77588778 0.779325667 0.768284181 0.958546566 1.044746516 0.59415557 0.771410256 1 10.58650055 -8.764713049 0.475957687 1.01718912 0.83823185 0 0.137243084 1.589322493 0.642233964 0.130551607 0.035783205 1.72E-09 8.764713049 -0.17895727 AALRYAGLDDT(ph)DS(ph)EDELPPGWEERT(ph)T(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 AALRYAGLDDTDSEDELPPGWEERTTK 27 2 H3BMD1;F5H3R5;Q9NZC7-4;Q9NZC7-3;Q9NZC7-7;Q9NZC7-5;Q9NZC7-6;Q9NZC7-2;Q9NZC7 H3BMD1 WWOX WW domain-containing oxidoreductase 4 0 AALRY(0.5)AGLDDT(0.75)DS(0.75)EDELPPGWEERT(1)T(1)K 43.162 0.014504 183180000 2900 2251.7 2330.3 2342.5 2706 3269.2 2854.9 2607.6 2534.5 2842 TRUE FALSE FALSE 2670.46194 2446.326915 2416.662968 2332.807356 2673.732717 2591.131069 2935.00081 3402.645236 2256.471691 2940.759288 0.908085864 0.831869145 0.821781972 0.793267019 0.909198086 0.881109542 0.99804184 1.1570635 0.767309212 1 11.52197298 -4.357469193 2.743181913 0.918234312 1.178135545 0.490690221 0.079949175 0.258933942 2.913907695 0.011650575 0.135214518 4.39E-05 4.357469193 0.259901233 AALSS(ph)SELLELGDSLMR ddPTM_HeLa_Curcumin_4h_R1 1 AALSSSELLELGDSLMR 17 0 Q9P2G1 Q9P2G1 ANKIB1 Ankyrin repeat and IBR domain-containing protein 1 1 0 AALS(0.256)S(0.549)S(0.196)ELLELGDSLMR 82.663 0.0093896 2978100 2670.9 2128.3 1992.8 2590.4 2292.8 619.47 626.07 469.39 2725.4 1828.9 TRUE FALSE FALSE 2459.495447 2312.260768 2066.654921 2579.681611 2265.459857 490.9849391 643.6358392 612.5048502 2426.430439 1892.454139 1.299632787 1.221831864 1.0920502 1.363140886 1.197101589 0.259443507 0.34010644 0.323656377 1.282160761 1 10.88604262 -5.262316171 24.99260248 1.167168985 0.310972501 0.938735061 0.105029515 16.567432 472257.4736 0.018884221 0.044661151 5.47E-06 5.262316171 -0.856196484 AAMEPIVISAK ddPTM_HeLa_Curcumin_4h_R1 1 AAMEPIVISAK 11 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 101.38 0.0090834 4107700 2619.8 2230.3 2244 2132.6 2394.8 2711.2 1830.9 1938.5 2448.5 2235.4 FALSE FALSE TRUE 2412.440066 2423.077194 2327.164614 2123.775866 2366.243574 2148.866558 1882.270126 2529.539726 2179.905676 2313.079984 1.042955748 1.047554434 1.006089124 0.918159286 1.022983896 0.929006595 0.813750558 1.093580743 0.94242555 1 11.17559944 -6.419435998 5.581072128 1.0230719 0.950185796 0.096921372 0.073489906 0.269934177 12.09546739 0.009984953 0.015296554 3.81E-07 6.419435998 -0.072886104 AAMYDIIS(ph)SPSKDSTK ddPTM_HeLa_Curcumin_4h_R1 1 AAMYDIISSPSKDSTK 16 1 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 1 0 AAMYDIIS(0.961)S(0.039)PS(0.001)KDSTK 207.4 1.49E-09 98101000 2059.9 1970.1 1954.5 2403.1 1755.3 2497.1 2446.8 952.05 2618.9 2241.8 TRUE FALSE FALSE 1896.856741 2140.386665 2026.935489 2393.156609 1734.369194 1979.173312 2515.450623 1242.325662 2331.613222 2319.702383 0.817715564 0.922698826 0.873791183 1.031665366 0.747668842 0.853201396 1.084385066 0.535553902 1.005134641 1 11.179724 -9.45218427 1.092752743 1.002795659 0.865415789 0.137921099 0.142917633 0.913548213 1.886361677 0.099255076 0.022680302 3.53E-10 9.45218427 -0.13737987 AAMYDIISS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 AAMYDIISSPSK 12 0 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 1 0 AAMYDIIS(0.117)S(0.883)PSK 112.13 0.0049477 18550000 1185.8 1130.6 1163.3 1229.1 1452.5 1458.3 1599.2 874.29 1294.4 1440.5 TRUE FALSE FALSE 1091.942679 1228.324026 1206.412921 1224.01431 1435.179886 1155.832142 1644.069248 1140.856996 1152.407558 1490.557268 0.732573449 0.824070334 0.809370393 0.821178989 0.962847867 0.775436252 1.102989656 0.765389577 0.773138734 1 10.54163609 -3.968956744 18.15634084 0.873149793 0.370858423 0.066286394 0.112005584 49579415.88 723170358.1 0.016992472 797371683 0.00010741 3.968956744 -0.50229137 AAMYDIISS(ph)PSKDSTK ddPTM_HeLa_Curcumin_4h_R1 2 AAMYDIISSPSKDSTK 16 1 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 1 0 AAMYDIIS(0.201)S(0.653)PS(0.141)KDS(0.004)T(0.001)K;AAMYDIIS(0.15)S(0.842)PS(0.008)KDSTK ; 171.11 0.0010546 136879000 7166.1 5410 6119.1 6226.5 5778.3 7290.4 5763.6 3292.2 6905.9 6684.4 TRUE FALSE FALSE 6598.895623 5877.616294 6345.879229 6200.736393 5709.397546 5778.28886 5925.311104 4295.976625 6148.340048 6916.682402 0.954055028 0.849773916 0.917474428 0.896489969 0.825453189 0.835413356 0.856669536 0.621103641 0.888914611 1 12.7558645 -2.231510783 0.223157944 1.006460405 8.27E-16 0.619853614 0.059361873 9.3940695 0.182579296 0.036040563 3.076714499 0.005867988 2.231510783 -1.006460405 AANMLQQS(ph)GSK ddPTM_HeLa_Curcumin_4h_R1 1 AANMLQQSGSK 11 0 P46063 P46063 RECQL ATP-dependent DNA helicase Q1 1 0 AANMLQQS(0.786)GS(0.214)K 115.24 0.004819 13421000 1944.6 1523.5 1896.8 2074.1 2133 3476.2 3586.8 1266.8 1875.4 1499.2 TRUE FALSE FALSE 1790.682858 1655.184551 1967.097077 2065.517924 2107.565368 2755.196935 3687.435955 1653.041488 1669.673312 1551.297088 1.154313298 1.066968129 1.268033758 1.331477987 1.358582688 1.776060147 2.377001789 1.065586663 1.0763079 1 10.59925929 -5.707768628 1.263749323 1.082556232 1.795708485 0.418768642 0.308745142 0.273518822 0.862125667 0.045479057 0.127707252 1.96E-06 5.707768628 0.713152254 AANQVEETLHTHLPQT(ph)PETNFR ddPTM_HeLa_Curcumin_4h_R1 1 AANQVEETLHTHLPQTPETNFR 22 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 0 AANQVEETLHT(0.002)HLPQT(0.911)PET(0.087)NFR 72.231 0.0011789 6812600 2977.4 3537.4 3333.2 2720.7 2972.6 4470.8 3692.2 2891.7 3891.9 4389.6 TRUE FALSE FALSE 2741.735648 3843.157094 3456.731324 2709.442464 2937.153686 3543.505684 3795.793195 3773.366018 3464.968307 4542.138273 0.603622233 0.846111867 0.761036128 0.596512546 0.646645591 0.780140425 0.835684201 0.83074662 0.762849587 1 12.14915591 -9.49791238 1.215597363 1.001572236 0.724095027 0.066582207 0.114230286 0.305311144 0.799992959 0.071235156 0.016890244 3.18E-10 9.49791238 -0.277477208 AANQVEETLHTHLPQTPET(ph)NFR ddPTM_HeLa_Curcumin_4h_R1 1 AANQVEETLHTHLPQTPETNFR 22 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 0 AANQVEETLHTHLPQT(0.483)PET(0.517)NFR 94.295 0.00013632 3920500 3836.9 4339.7 3618.4 3546.3 3950.7 5478.2 4524.8 3193.8 5433.5 5061.9 TRUE FALSE FALSE 3533.205316 4714.804331 3752.501087 3531.62635 3903.590483 4341.959568 4651.75371 4167.574918 4837.458644 5237.800648 0.674558952 0.900149633 0.716426863 0.674257496 0.745272824 0.828966175 0.888112019 0.795672687 0.923566773 1 12.35474544 -9.482946048 1.184345067 1.001888928 0.76961566 0.458100397 0.078351521 0.30840877 0.763804122 0.05923373 0.014003863 3.29E-10 9.482946048 -0.232273268 AAPAPGK(ac)VGDVTPQVK ddPTM_HeLa_Curcumin_4h_R1 2 AAPAPGKVGDVTPQVK 16 1 E7ETY2;Q13428-6;Q13428-7;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4 E7ETY2;Q13428 TCOF1 Treacle protein 0 1 ; AAPAPGK(1)VGDVTPQVK;AAPAPGK(1)VGDVTPQVK 189.3 4.55E-09 5150700 2582 2239.9 2345 2242.97 2580.4 3386.6 2918.2 2522.9 2726.3 2645.3 FALSE TRUE FALSE 2377.631975 2433.506975 2431.907763 2233.689184 2549.630415 2684.180985 3000.076838 3292.120596 2427.231711 2737.223978 0.868628945 0.889041962 0.888457716 0.816041801 0.931465761 0.98062161 1.096028992 1.202722401 0.886749397 1 11.41849778 -4.638765358 1.726174363 0.919464595 1.214774475 0.814316396 0.048116907 0.2143154 1.013864553 0.009345116 0.081817685 2.30E-05 4.638765358 0.29530988 AAPEAS(ph)SPPAS(ph)PLQHLLPGK ddPTM_HeLa_Curcumin_4h_R1 5 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 2 0 AAPEAS(0.5)S(0.5)PPAS(1)PLQHLLPGK;AAPEAS(0.708)S(0.295)PPAS(0.997)PLQHLLPGK;AAPEAS(0.5)S(0.5)PPAS(1)PLQHLLPGK;AAPEAS(0.581)S(0.425)PPAS(0.994)PLQHLLPGK;AAPEAS(0.5)S(0.5)PPAS(1)PLQHLLPGK ;;;; 119.38 0.0002564 896336000 23838.4 20215 20000.3 21020.9 19799.2 27793.7 23451.7 36191.6 25765.5 24137.8 TRUE FALSE FALSE 21951.56549 21962.29452 20741.52871 20933.92109 19563.10747 22028.97332 24109.69158 47226.25223 22939.08911 24976.58675 0.878885722 0.879315286 0.830438879 0.838141788 0.783257843 0.881984938 0.965291688 1.8908209 0.918423696 1 14.60828871 -4.261084124 4.660821091 0.907325909 1.950541505 0.960772428 0.060876416 0.033475478 1.955769427 0.011219442 0.113502932 5.48E-05 4.261084124 1.043215596 AAPEAS(ph)SPPASPLQHLLPGK ddPTM_HeLa_Curcumin_4h_R1 3 AAPEASSPPASPLQHLLPGK 20 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 0 AAPEAS(0.876)S(0.121)PPAS(0.003)PLQHLLPGK;AAPEAS(0.804)S(0.196)PPASPLQHLLPGK;AAPEAS(0.546)S(0.435)PPAS(0.019)PLQHLLPGK ;; 130.89 4.06E-05 1718083000 7763.1 6897.1 6167.8 6727.4 7817.9 12325.6 7906.3 7286.7 10033.3 7494.6 TRUE FALSE FALSE 7148.642443 7493.254591 6396.384094 6699.563801 7724.676649 9769.131622 8128.129499 9508.381286 8932.672092 7755.036792 0.921806387 0.96624359 0.824803836 0.86389839 0.996085106 1.259714413 1.048109728 1.226091061 1.151854251 1 12.92091791 -5.421289723 5.626964326 0.944209364 1.163344105 0.511426018 0.097291899 0.107921293 4.912251029 0.01067931 0.024133525 3.79E-06 5.421289723 0.219134741 AAPGAEFAPNK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 AAPGAEFAPNKR 12 1 Q15233;Q15233-2 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 1 ; AAPGAEFAPNK(1)R;AAPGAEFAPNK(1)R 144.77 3.02E-05 209400000 2406.8 2177.93 2213.1 1828.32 2046.41 2793.2 2082.79 3064.7 2076.03 2039.49 FALSE TRUE FALSE 2216.29924 2366.180565 2295.119433 1820.754896 2022.007897 2213.858834 2141.227482 3999.112922 1848.294703 2110.362126 1.050198548 1.121220162 1.08754768 0.862768941 0.958133143 1.049042156 1.014625621 1.894988956 0.875818742 1 11.04327486 -4.261183899 24.94686601 1.021038309 1.894989222 0.914620864 0.081653626 3.4746105 339090.461 0.009605197 0.075018916 5.48E-05 4.261183899 0.873950913 AAPGAEFAPNKR ddPTM_HeLa_Curcumin_4h_R1 2 AAPGAEFAPNKR 12 1 Q15233;Q15233-2 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 0 ; ; 105.2 0.0014334 12981300 9067 6711 7914.7 7532.1 7753.8 10283.8 7491.5 7430.1 8856.1 8176.3 FALSE FALSE TRUE 8349.337383 7291.068936 8208.025744 7500.934166 7661.340999 8150.823958 7701.691328 9695.503286 7884.607987 8460.425816 0.98686964 0.861785103 0.970166978 0.88659062 0.905550284 0.963405878 0.910319586 1.145982897 0.931939852 1 13.04651456 -7.491231335 24.40131004 0.99420724 0.943431861 0 0.076472211 522.6938229 403020.7178 0.01198021 0.013130512 3.23E-08 7.491231335 -0.050775379 AAPPPPPPPPPLES(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 4 AAPPPPPPPPPLESSPR 17 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 0 AAPPPPPPPPPLES(0.5)S(0.5)PR;AAPPPPPPPPPLES(0.5)S(0.5)PR;AAPPPPPPPPPLES(0.5)S(0.5)PR;AAPPPPPPPPPLES(0.5)S(0.5)PR ;;; 172.42 4.63E-05 142472000 2023.51 1663.91 2282.81 2365.39 1937.31 2521.38 1447.05 1272.39 2510.48 2236.17 TRUE FALSE FALSE 1863.347048 1807.730966 2367.412947 2355.602643 1914.208844 1998.417366 1487.650328 1660.335854 2235.086625 2313.876741 0.805292268 0.78125638 1.023137017 1.018032897 0.827273471 0.863666301 0.642925486 0.717555877 0.965948871 1 11.1760963 -4.871686617 3.61805305 0.907474505 0.679197124 0.535861989 0.086148403 0.157131811 3.897902198 0.014283922 0.049627471 1.34E-05 4.871686617 -0.228277381 AAPQS(ph)PSVPK ddPTM_HeLa_Curcumin_4h_R1 1 AAPQSPSVPK 10 0 E9PF10;O75694-2;O75694 E9PF10 NUP155 Nuclear pore complex protein Nup155 1 0 AAPQS(0.5)PS(0.5)VPK 131.12 0.0027619 10376000 1698.4 1591.8 1870.7 1766.9 1700.9 2323.9 1655.5 1414.6 1863.9 1707.5 TRUE FALSE FALSE 1563.969848 1729.388099 1940.029788 1759.589036 1680.617878 1841.896944 1701.948874 1845.905028 1659.434833 1766.835498 0.885181359 0.978805385 1.098025136 0.995898621 0.951202237 1.042483551 0.963275232 1.044752061 0.93921298 1 10.78695201 -6.999676095 24.99848657 0.945054468 1.013191694 0.333020868 0.047246272 12.49368747 964131.8862 0.0090921 0.011886492 1.00E-07 6.999676095 0.068137226 AAPQSPS(ph)VPK ddPTM_HeLa_Curcumin_4h_R1 2 AAPQSPSVPK 10 0 E9PF10;O75694-2;O75694 E9PF10 NUP155 Nuclear pore complex protein Nup155 1 0 AAPQS(0.137)PS(0.863)VPK;AAPQS(0.255)PS(0.745)VPK ; 139.76 0.0015533 688390000 15603.4 13492.6 14580.7 13853.4 15339 16718 14369.8 12200.6 12782.2 11754.7 TRUE FALSE FALSE 14368.37443 14658.84022 15121.07357 13796.0783 15156.09244 13250.49835 14772.97791 15920.50678 11380.02464 12163.17495 1.181301304 1.205182058 1.243184747 1.134249763 1.246063837 1.089394702 1.214565932 1.308910448 0.935613003 1 13.57023224 -9.060914966 0.539903186 0.971800824 1.206510223 0.695987697 0.061249291 0.581659236 0.265053889 0.068886262 0.014307371 8.69E-10 9.060914966 0.234709399 AAPRPAPVAQPPAAAPPSAVGSSAAAPR ddPTM_HeLa_Curcumin_4h_R1 2 AAPRPAPVAQPPAAAPPSAVGSSAAAPR 28 1 Q9Y6H1;Q5T1J5 Q9Y6H1 CHCHD2;CHCHD2P9 "Coiled-coil-helix-coiled-coil-helix domain-containing protein 2;Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial" 0 0 ; ; 96.133 1.29E-07 5620100 940.6 711.3 777.84 894.27 885.55 1278.39 562.95 497.85 1177.55 1132.53 FALSE FALSE TRUE 866.1505175 772.7816025 806.6674347 890.5697477 874.9903946 1013.237504 578.7448619 649.6421732 1048.375711 1171.885333 0.739108591 0.659434486 0.688350141 0.75994615 0.746651886 0.864621712 0.493857927 0.554356433 0.894606052 1 10.1946157 -13.52287875 0.14222765 2.152792398 0.569422743 0.52801428 0.09995599 35.92857621 0.353924494 11.54711074 0.276402338 3.00E-14 13.52287875 -1.583369655 AAPSTAPAEAT(ph)PPKPGEAEAPPK ddPTM_HeLa_Curcumin_4h_R1 2 AAPSTAPAEATPPKPGEAEAPPK 23 1 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 0 AAPS(0.014)T(0.012)APAEAT(0.974)PPKPGEAEAPPK;AAPSTAPAEAT(1)PPKPGEAEAPPK ; 119.37 3.96E-06 76260000 5774.8 5333.3 5631.5 5652.6 7206.2 6883.6 5815.4 4248.1 5010 4695.3 TRUE FALSE FALSE 5317.718486 5794.286687 5840.208344 5629.211039 7120.270772 5455.863766 5978.564473 5543.326134 4460.415534 4858.461326 1.094527286 1.192617641 1.202069535 1.158640702 1.46554028 1.122961242 1.23054689 1.140963314 0.918071635 1 12.24628377 -7.503603989 0.852088787 1.021379007 1.230962486 0.513824596 0.096305369 0.316169684 0.476827143 0.022344775 0.023076344 3.14E-08 7.503603989 0.20958348 AAPSTAPAEAT(ph)PPKPGEAEAPPKHPGVLK ddPTM_HeLa_Curcumin_4h_R1 1 AAPSTAPAEATPPKPGEAEAPPKHPGVLK 29 2 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 0 AAPS(0.007)T(0.04)APAEAT(0.953)PPKPGEAEAPPKHPGVLK 85.17 2.02E-06 78998000 3405.5 2983.1 2847 3034.5 3166.8 4189.5 2682.5 2349.8 3662.7 3148.7 TRUE FALSE FALSE 3135.951082 3240.945872 2952.512324 3021.944043 3129.037978 3320.550475 2757.76373 3066.243203 3260.910974 3258.117091 0.962504107 0.994729711 0.906202031 0.927512413 0.960382298 1.019162413 0.846428675 0.941108965 1.000857515 1 11.66982274 -6.220617585 0.010809341 1.897918192 8.97E-08 0.25930835 0.043047263 1819.399941 7.66491006 653.5189661 692.0028614 6.02E-07 6.220617585 -1.897918102 AAPWGSNPS(ph)PSAESTQAMDR ddPTM_HeLa_Curcumin_4h_R1 2 AAPWGSNPSPSAESTQAMDR 20 0 Q96N67-2;Q96N67-6;Q96N67;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 AAPWGSNPS(0.912)PS(0.087)AES(0.001)TQAMDR;AAPWGSNPS(0.803)PS(0.044)AES(0.006)T(0.147)QAMDR ; 169.6 2.70E-06 27358400 3469.8 2497.8 2926.9 2957 3005.6 3490.5 1895.9 2096.97 3875.1 3111.1 TRUE FALSE FALSE 3195.161669 2713.698702 3035.373489 2944.764718 2969.760183 2766.530954 1949.093851 2736.3265 3450.011225 3219.210493 0.992529589 0.842970259 0.942893761 0.91474749 0.92251196 0.859381814 0.605457101 0.849999248 1.071694825 1 11.6524912 -5.064408982 0.421587907 1.000988098 0.639843011 0.544320046 0.081219021 1.45681612 0.273454892 0.020936935 0.236168513 8.62E-06 5.064408982 -0.361145087 AAQDRDQIYR ddPTM_HeLa_Curcumin_4h_R1 2 AAQDRDQIYR 10 1 P62995;H7C2L4;P62995-3 P62995 TRA2B Transformer-2 protein homolog beta 0 0 ; ; 123.35 0.0011657 5251500 3791.3 3017.6 3776.5 3421.9 3215.2 4497.6 3611.2 3932.3 3953.9 3224.1 FALSE FALSE TRUE 3491.214604 3278.427898 3916.460412 3407.741084 3176.86084 3564.747062 3712.520553 5131.240168 3520.167062 3336.137235 1.04648411 0.98270175 1.173950631 1.021463101 0.952257241 1.068525307 1.112820094 1.538078264 1.055162547 1 11.70396292 -4.185146143 2.186098152 1.027626808 1.741493921 0.871959095 0.057132677 0.200046323 0.902321852 0.007785131 0.297060233 6.53E-05 4.185146143 0.713867112 AAQEEYVK ddPTM_HeLa_Curcumin_4h_R1 2 AAQEEYVK 8 0 P04075;H3BQN4;J3KPS3;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 ; ; 130.56 0.0016082 21754000 10456.5 7988.1 9246.7 8670.8 11096 11271.3 9858.2 8663.7 8800.1 8619.9 FALSE FALSE TRUE 9628.856991 8678.55577 9589.390836 8634.922527 10963.68745 8933.505326 10134.79456 11305.22225 7834.751047 8919.440883 1.079535939 0.97299325 1.075111205 0.968101324 1.22918999 1.00157683 1.136258953 1.267481044 0.878390378 1 13.12273756 -1.000000001 0.5881059 1.0347871 14.15423545 0.43637326 0.086938907 90.72152892 0.672614758 0.01200734 1528.921003 0.1 1.000000001 13.11944835 AAQEEYVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 AAQEEYVKR 9 1 P04075;H3BQN4;J3KPS3;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 1 ; AAQEEYVK(1)R;AAQEEYVK(1)R 140.45 6.39E-06 77645000 4325.4 5501.4 3945.1 4077.2 7611.8 10885.6 7847.3 7946.3 11187.9 4382.4 FALSE TRUE FALSE 3983.040026 5976.916502 4091.308876 4060.329627 7521.034256 8627.803854 8067.474118 10369.09029 9960.615361 4534.688074 0.878349285 1.31804358 0.902224984 0.895393368 1.658556032 1.902623447 1.779058226 2.286615997 2.196538152 1 12.1467876 -5.618124338 3.025674239 0.964868153 1.958554835 0.341745393 0.426095008 0.060790089 1.115566792 0.025019313 0.054339564 2.41E-06 5.618124338 0.993686682 AAQEEYVKR ddPTM_HeLa_Curcumin_4h_R1 1 AAQEEYVKR 9 1 P04075;H3BQN4;J3KPS3;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 78.556 0.013491 30333000 5848.2 4461.5 4988.6 4960.3 5328.7 6356.1 4785.3 4965.1 6230.5 5226.8 FALSE FALSE TRUE 5385.308799 4847.13218 5173.481904 4939.775593 5265.158733 5037.773212 4919.562639 6478.936133 5547.029738 5408.430911 0.995724802 0.896217824 0.956558749 0.913347267 0.973509474 0.931466685 0.909609963 1.19793268 1.025626439 1 12.40099439 -4.251468644 24.84188151 0.972271272 1.197932814 0.723201155 0.043888228 588.7632906 1466859.803 0.006576251 0.117969219 5.60E-05 4.251468644 0.225661542 AAQK(ac)TLLVSTSAVDNNEAQKK ddPTM_HeLa_Curcumin_4h_R1 1 AAQKTLLVSTSAVDNNEAQKK 21 2 A0A087X0H9;Q5T8P6-5;Q5T8P6-4;Q5T8P6-3;Q5T8P6-2;Q5T8P6 A0A087X0H9 RBM26 RNA-binding protein 26 0 1 AAQK(1)TLLVSTSAVDNNEAQKK 160.95 1.78E-05 7477300 1726 1421.2 1486.6 1400.7 1170.6 1668.7 1244.3 1413.9 1923.5 1582.2 FALSE TRUE FALSE 1589.385279 1544.042195 1541.694704 1394.904275 1156.64136 1322.59281 1279.211709 1844.991601 1712.496862 1637.181332 0.970805889 0.943110067 0.941676205 0.852015746 0.706483355 0.807847478 0.781350046 1.126931736 1.046003169 1 10.67699841 -6.443721254 2.298055556 0.982982294 0.839882357 0.265472781 0.105189704 0.286460046 2.982495213 0.015978842 0.025479541 3.60E-07 6.443721254 -0.143099938 AAQQAASSSGQGQQAQT(ph)PTGK ddPTM_HeLa_Curcumin_4h_R1 5 AAQQAASSSGQGQQAQTPTGK 21 0 H0Y9X2;U3KQK7;U3KPX3;A0A590UJ43;P48729;P48729-2 H0Y9X2 CSNK1A1 Casein kinase I isoform alpha 1 0 AAQQAASSSGQGQQAQT(0.998)PT(0.002)GK;AAQQAASSSGQGQQAQT(0.989)PT(0.011)GK;AAQQAASSSGQGQQAQT(0.999)PT(0.001)GK;AAQQAASSSGQGQQAQT(0.694)PT(0.306)GK;AAQQAASSSGQGQQAQT(0.99)PT(0.01)GK ;;;; 279.1 1.28E-72 16043900 6190.76 5524.44 5383.83 5939.45 5557.82 10104.6 8330.58 4054.42 6795.17 5227.64 TRUE FALSE FALSE 5700.754814 6001.947977 5583.359476 5914.87413 5491.546626 8008.792058 8564.313654 5290.593994 6049.756852 5409.300101 1.0538803 1.109560916 1.0321778 1.093463853 1.015204652 1.48055976 1.58325726 0.978055182 1.11839919 1 12.40122622 -5.270848904 24.74448577 1.037620563 1.370887387 0.423099237 0.151154561 309.3875174 813605.4004 0.019471485 0.044084014 5.36E-06 5.270848904 0.333266824 AAQQQQPSAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 AAQQQQPSASPR 12 0 Q86U86-8;Q86U86 Q86U86-8 PBRM1 Protein polybromo-1 1 0 AAQQQQPSAS(1)PR;AAQQQQPSAS(1)PR;AAQQQQPS(0.071)AS(0.929)PR;AAQQQQPS(0.05)AS(0.95)PR ;;; 222.81 8.23E-14 76590590 5653.66 4906.367 4758.492 5699.024 5446.86 5794.52 4173.926 3865.68 6306.04 5226.02 TRUE FALSE FALSE 5206.166845 5330.451501 4934.8459 5675.442949 5381.909752 4592.671234 4291.03513 5044.308037 5614.283189 5407.623806 0.962745752 0.98572898 0.912571968 1.049526216 0.995244852 0.849295624 0.793515837 0.932814156 1.038216302 1 12.40077908 -5.258842943 24.81859341 0.982816669 0.852039259 0.611878156 0.048240807 93.5010719 893743.3271 0.006010681 0.014578672 5.51E-06 5.258842943 -0.13077741 AAS(ph)ADSTTEGTPADGFTVLSTK ddPTM_HeLa_Curcumin_4h_R1 1 AASADSTTEGTPADGFTVLSTK 22 0 O75367-2;O75367-3;O75367 O75367-2 H2AFY Core histone macro-H2A.1 1 0 AAS(0.426)ADS(0.35)T(0.105)T(0.105)EGT(0.014)PADGFT(0.001)VLSTK 48.656 0.016494 2472900 1027.9 955.9 1051.4 1142 1137.9 1291 1078 1225.3 1088.1 883.97 TRUE FALSE FALSE 946.5406304 1038.523737 1090.365809 1137.274707 1124.331286 1023.232047 1108.245779 1598.888329 968.7381523 914.6878917 1.034823615 1.135385902 1.192063237 1.243347285 1.229196643 1.11866797 1.211610855 1.748015191 1.059091479 1 9.837135743 -1 0.468073704 1.037541595 16.38464004 0.743575919 0.101415946 30.64894724 0.317974821 0.022554616 458.0260324 0.1 1 15.34709845 ESSPLY(ph)SPTFSDSTSAVKEK ddPTM_HeLa_Curcumin_4h_R1 2 ESSPLYSPTFSDSTSAVKEK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 ES(0.087)S(0.244)PLY(0.553)S(0.101)PT(0.015)FSDSTSAVKEK;ES(0.154)S(0.301)PLY(0.541)S(0.004)PTFSDSTSAVKEK ; 149.95 0.00014627 72154000 6781.2 4269.5 3135.9 4386.6 1448.74 4419.2 1712.99 1956.11 10336.3 8011.5 TRUE FALSE FALSE 6244.460865 4638.536555 3252.119213 4368.449411 1431.464722 3502.608105 1761.051889 2552.518934 9202.43375 8289.899029 0.75326139 0.559540778 0.392299014 0.526960509 0.172675773 0.422515171 0.212433455 0.30790712 1.110077905 1 13.01713881 -7.182834228 0.519856241 0.978394227 0.251180159 0.889887112 0.100321119 0.152268676 0.095743191 0.03064525 0.03874471 6.56E-08 7.182834228 -0.727214068 AAS(ph)ALLLR ddPTM_HeLa_Curcumin_4h_R1 1 AASALLLR 8 0 F5H672;F5H5N2;B4DNC9;B3KQ30;Q9H1K1 F5H672 ISCU "Iron-sulfur cluster assembly enzyme ISCU, mitochondrial" 1 0 AAS(1)ALLLR 113.62 0.010237 10815000 3618.6 2727.2 3055.1 3015.4 3089.1 3692 3249.9 2904.7 3436.1 3309 TRUE FALSE FALSE 3332.183992 2962.927016 3168.324694 3002.923074 3052.2645 2926.237583 3341.083447 3790.329658 3059.168427 3423.987504 0.973188129 0.865343992 0.925331851 0.877025127 0.891435642 0.854628581 0.975787278 1.106992842 0.893451984 1 11.74146172 -7.470865979 9.588816657 0.988219115 0.923263004 0 0.075403018 0.710375337 127.4592966 0.01204129 0.013635211 3.38E-08 7.470865979 -0.06495611 EDSGT(ph)FSLGK ddPTM_HeLa_Curcumin_4h_R1 1 EDSGTFSLGK 10 0 G5E9Q4;O75569 G5E9Q4 PRKRA Interferon-inducible double-stranded RNA-dependent protein kinase activator A 1 0 EDS(0.368)GT(0.632)FSLGK 134.38 0.0066675 92354000 2987.2 2336.4 3115.7 2135.4 3305.4 6150 6933.9 5167.9 2615.2 2973.4 TRUE FALSE FALSE 2750.759968 2538.348005 3231.170583 2126.564281 3265.985264 4874.420675 7128.446572 6743.56892 2328.319103 3076.725429 0.89405442 0.825016097 1.0501979 0.691177789 1.061513398 1.584288487 2.316893963 2.191800691 0.756752319 1 11.58717999 -5.023143835 2.222978406 0.929660071 2.277909947 0.951500787 0.123329864 0.040328054 0.386042072 0.01572373 0.058672706 9.48E-06 5.023143835 1.348249877 up AAS(ph)EELLEK ddPTM_HeLa_Curcumin_4h_R1 1 AASEELLEK 9 0 F8VY01;Q6ZV73-2;Q6ZV73 F8VY01 FGD6 "FYVE, RhoGEF and PH domain-containing protein 6" 1 0 AAS(1)EELLEK 109.39 0.0093475 20979000 4698.8 3521.5 4018.8 4194.8 3860.8 5020.5 3945.8 2774.1 4902.2 4016.2 TRUE FALSE FALSE 4326.885022 3825.882769 4167.740263 4177.443029 3814.762482 3979.191707 4056.508528 3619.91032 4364.440925 4155.762651 1.041177128 0.920621096 1.002882169 1.005216943 0.917945225 0.957511783 0.976116508 0.871058004 1.050214194 1 12.02089754 -1 0.271923122 1.019557657 0.119860761 0.488574534 0.038953899 30.64245596 0.389023305 0.018024171 13.14021661 0.1 1 -0.899696896 AAS(ph)LDER ddPTM_HeLa_Curcumin_4h_R1 1 AASLDER 7 0 B9ZVR7;Q15772-1;Q15772 B9ZVR7 SPEG Striated muscle preferentially expressed protein kinase 1 0 AAS(1)LDER 101.25 0.018973 13008000 6200.2 4257.6 5036 5746.9 5610.1 8604.8 7785.7 5846.9 6749.7 5413.3 TRUE FALSE FALSE 5709.447628 4625.607973 5222.63859 5723.120851 5543.203222 6820.067484 8004.145788 7629.592894 6009.274797 5601.411772 1.019287255 0.825793239 0.932378979 1.021728286 0.989608236 1.217562243 1.428951506 1.362083918 1.072814326 1 12.45157477 -5.059618084 2.561694125 0.988321885 1.39703881 0.868883624 0.065567686 0.069879717 0.892714649 0.009331712 0.03117259 8.72E-06 5.059618084 0.408716925 AAS(ph)LDSVATSR ddPTM_HeLa_Curcumin_4h_R1 2 AASLDSVATSR 11 0 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4;Q9Y2J4-3 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 0 AAS(0.976)LDS(0.024)VATSR;AAS(0.993)LDS(0.007)VATSR ; 187.78 5.62E-05 142943000 2523.81 2044.15 2224.84 2392.35 2250.01 2978.42 2246.54 1688.6 2467.15 2060.78 TRUE FALSE FALSE 2324.047775 2220.837217 2307.294528 2382.45109 2223.1801 2360.662118 2309.571866 2203.446367 2196.509818 2132.391952 1.089878328 1.041477021 1.082021776 1.117266968 1.042575732 1.107048878 1.08308975 1.033321461 1.030068518 1 11.05825693 -9.360040802 0.800067847 0.993491814 1.076867572 0.400863365 0.028108077 0.466811636 0.465705136 0.02580719 0.004965568 4.36E-10 9.360040802 0.083375758 AAS(ph)LGSSQSSR ddPTM_HeLa_Curcumin_4h_R1 1 AASLGSSQSSR 11 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;F8W7E0;E9PSG1;H0YA91;H0Y944;D6RBR1;D6RGF7;E7EN75 P20810-6 CAST Calpastatin 1 0 AAS(0.999)LGSS(0.001)QSSR 148.78 0.00072571 29334000 2436.4 1834.9 2113 2353 1880.6 3377.3 2536 2230.6 2409.7 2008.5 TRUE FALSE FALSE 2243.556369 1993.50058 2191.309639 2343.263909 1858.175073 2676.80991 2607.153335 2910.699672 2145.361939 2078.295226 1.079517646 0.959199904 1.054378421 1.127493284 0.894086196 1.287983477 1.254467269 1.400522715 1.032270061 1 11.02118489 -5.168917675 6.892585277 1.032422972 1.312241745 0.786951439 0.069813794 0.086375432 5.52948113 0.009402595 0.024215237 6.78E-06 5.168917675 0.279818773 AAS(ph)LNYLNQPSAAPLQVSR ddPTM_HeLa_Curcumin_4h_R1 1 AASLNYLNQPSAAPLQVSR 19 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 0 AAS(0.999)LNYLNQPS(0.001)AAPLQVSR 181.49 2.67E-07 164250000 886.56 851.98 1101.6 1072.2 902.94 1300 1013.7 1018 1422.4 1073.5 TRUE FALSE FALSE 816.3878405 925.6213549 1142.426265 1067.76352 892.1730302 1030.365346 1042.141694 1328.383514 1266.366279 1110.804045 0.734952167 0.833289507 1.028467865 0.96125282 0.803177693 0.927585158 0.938186801 1.195875654 1.140044713 1 10.11738862 -4.081596106 1.761880451 0.88357485 1.422579984 0.256043097 0.117957488 1.221704218 2.554447595 0.016230613 1.269613818 8.29E-05 4.081596106 0.539005134 AAS(ph)PAKPSSLDLVPNLPK ddPTM_HeLa_Curcumin_4h_R1 1 AASPAKPSSLDLVPNLPK 18 1 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 0 AAS(0.519)PAKPS(0.022)S(0.46)LDLVPNLPK 85.7 0.0019176 727470000 6658.4 4664 5854.3 6392.2 5491.1 5711.8 3665.4 2979.8 6458 5498.4 TRUE FALSE FALSE 6131.380614 5067.135378 6071.265508 6365.75077 5425.622219 4527.108295 3768.241259 3888.327303 5749.573557 5689.468991 1.077671857 0.890616574 1.067105826 1.118865536 0.953625413 0.795699617 0.662318622 0.683425344 1.010564179 1 12.47407829 -5.177233092 2.164673497 1.033114963 0.673385498 0.85400574 0.059206143 0.083678578 0.752079821 0.008907853 0.028979134 6.65E-06 5.177233092 -0.359729465 AAS(ph)PESASSTPESLQAR ddPTM_HeLa_Curcumin_4h_R1 4 AASPESASSTPESLQAR 17 0 Q96BT3 Q96BT3 CENPT Centromere protein T 1 0 AAS(0.999)PES(0.001)ASSTPESLQAR;AAS(1)PESASSTPESLQAR;AAS(0.955)PES(0.045)ASSTPESLQAR;AAS(1)PESASSTPESLQAR ;;; 257.16 1.12E-40 107086800 7443.2 6089 6632.1 6741.8 6973.37 8397 6232.53 5525.59 7556.3 6428.4 TRUE FALSE FALSE 6854.062866 6615.306028 6877.89146 6713.904218 6890.217117 6655.367546 6407.398018 7210.316954 6727.392795 6651.786422 1.030409341 0.9945157 1.033991626 1.009338513 1.035844611 1.00053837 0.963259734 1.083966997 1.011366326 1 12.69952613 VEVKVPPAPVPCPPPSPGPSAVPSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 VEVKVPPAPVPCPPPSPGPSAVPSSPK 27 1 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 0 VEVKVPPAPVPCPPPS(0.001)PGPS(0.14)AVPS(0.246)S(0.613)PK 90.041 4.10E-06 20857000 2366.9 1658.3 1501.9 2160.5 967.79 2008.9 1253 956.9 2958.1 2612.6 TRUE FALSE FALSE 2179.557367 1801.636063 1557.561735 2151.560423 956.2497363 1592.231495 1288.155808 1248.654405 2633.603831 2703.387656 0.806231901 0.666436447 0.576151826 0.795875656 0.353722758 0.588976387 0.476496889 0.461885073 0.974186527 1 11.40055269 -7.099254135 0.336492068 1.027906677 0.410104413 0.781819857 0.09708495 0.394857331 0.12980127 0.068367964 0.091422024 7.96E-08 7.099254135 -0.617802264 AAS(ph)PPASASDLIEQQQK ddPTM_HeLa_Curcumin_4h_R1 2 AASPPASASDLIEQQQK 17 0 Q5VSL9;Q5VSL9-3;Q5VSL9-2 Q5VSL9 STRIP1 Striatin-interacting protein 1 1 0 AAS(0.871)PPAS(0.129)ASDLIEQQQK;AAS(0.958)PPAS(0.025)AS(0.017)DLIEQQQK ; 130.47 0.00034312 285436000 4339.7 3781.7 4361.6 4088.9 4277.2 5088.3 3768.1 3144.5 4286.8 4209 TRUE FALSE FALSE 3996.208166 4108.573297 4523.244733 4071.981215 4226.197184 4032.929223 3873.822745 4103.243575 3816.548765 4355.262437 0.917558522 0.943358375 1.03856996 0.934956567 0.970365677 0.925989945 0.889457938 0.942134632 0.876307414 1 12.08854394 -5.156740077 4.404595379 0.963346181 0.914181509 0.097278521 0.043994366 0.269749754 8.747232169 0.005723559 0.01532839 6.97E-06 5.156740077 -0.049164672 AAS(ph)PPASASDLIEQQQKR ddPTM_HeLa_Curcumin_4h_R1 2 AASPPASASDLIEQQQKR 18 1 Q5VSL9;Q5VSL9-3;Q5VSL9-2 Q5VSL9 STRIP1 Striatin-interacting protein 1 1 0 AAS(1)PPASASDLIEQQQKR;AAS(0.939)PPAS(0.038)AS(0.023)DLIEQQQKR ; 157.88 2.04E-05 121930000 7008.3 5624.8 5286.9 6040.4 4435.4 7671.6 4706.2 5191.7 8775.8 7178.8 TRUE FALSE FALSE 6453.58566 6110.982648 5482.837165 6015.406425 4382.510752 6080.423683 4838.243306 6774.62543 7813.116696 7428.262766 0.868788015 0.822666462 0.738104903 0.809799897 0.589977884 0.818552584 0.651329047 0.912006703 1.051809413 1 12.85880913 -7.733168257 0.621121755 0.98410734 0.739555452 0.571082768 0.089021579 0.332582718 0.293317626 0.029496519 0.024367543 1.85E-08 7.733168257 -0.244551888 AAS(ph)PSPQSVR ddPTM_HeLa_Curcumin_4h_R1 5 AASPSPQSVR 10 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 AAS(0.992)PS(0.008)PQSVR;AAS(0.601)PS(0.398)PQS(0.001)VR;AAS(0.988)PS(0.011)PQS(0.001)VR;AAS(0.756)PS(0.236)PQS(0.008)VR;AAS(0.999)PS(0.001)PQSVR ;;;; 147.28 0.00099567 1360267200 17111 13870.2 14605 15372 15142.3 17779.2 13737.7 13662.3 16499.4 14884.3 TRUE FALSE FALSE 15756.64629 15069.07828 15146.27415 15308.39474 14961.73796 14091.59351 14123.14289 17827.87238 14689.4571 15401.52832 1.023057321 0.978414478 0.983426699 0.993952965 0.971445019 0.914947739 0.916996197 1.157539175 0.953766198 1 13.9107859 -7.249743416 22.8135269 1.010888179 0.981959053 0 0.065831411 619.4207932 1208203.086 0.009957312 0.012131138 5.63E-08 7.249743416 -0.028929126 AAS(ph)PSPQSVRR ddPTM_HeLa_Curcumin_4h_R1 2 AASPSPQSVRR 11 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 AAS(0.998)PS(0.002)PQSVRR;AAS(1)PSPQSVRR ; 83.087 0.011583 7651300 1241.13 610.26 677.73 761.84 559.22 1004.42 745.12 617.36 1411.64 1184.72 TRUE FALSE FALSE 1142.893251 663.0081551 702.84727 758.6877079 552.5516667 796.0919699 766.0260618 805.590222 1256.786624 1225.888932 0.932297553 0.540838683 0.573336827 0.618887803 0.450735505 0.649399753 0.624873952 0.657147806 1.025204316 1 10.25961256 -7.304601006 5.485444534 0.969620697 0.58684472 0.899340366 0.060971779 0.041895654 3.211938566 0.010401536 0.011964614 4.96E-08 7.304601006 -0.382775977 VVIKSEAAS(ph)PALPVITK ddPTM_HeLa_Curcumin_4h_R1 1 VVIKSEAASPALPVITK 17 1 Q99958 Q99958 FOXC2 Forkhead box protein C2 1 0 VVIKS(0.026)EAAS(0.972)PALPVIT(0.002)K 63.044 0.012877 11954000 1495.8 1208.6 838.29 1051 403.81 1246.7 800.98 379.15 2340.5 1597.8 TRUE FALSE FALSE 1377.405852 1313.065999 869.3577648 1046.65124 398.9948295 988.1203668 823.4533431 494.7510896 2083.753006 1653.323431 0.833113368 0.794197901 0.525824378 0.633058977 0.241328963 0.597657027 0.498059441 0.299246403 1.260342028 1 10.69115326 -6.864811109 0.648991411 0.963170889 0.40649939 0.754748347 0.146705715 0.207027856 0.181426908 0.02778273 0.044289746 1.37E-07 6.864811109 -0.556671499 SDS(ph)RAQAVSEDAGGNEGR ddPTM_HeLa_Curcumin_4h_R1 1 SDSRAQAVSEDAGGNEGR 18 1 P55884-2;P55884;C9JZG1 P55884-2 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 0 S(0.001)DS(0.999)RAQAVSEDAGGNEGR 133.95 0.0025116 26630000 1584.4 1512.3 940.82 1040 509.41 475.32 362.76 155.37 1993.8 1695.8 TRUE FALSE FALSE 1458.993068 1643.016473 975.6876168 1035.696756 503.3356185 376.733274 372.9380693 202.7415978 1775.085128 1754.728924 0.831463509 0.936336349 0.556033245 0.590231768 0.286845228 0.214695996 0.212533152 0.115540124 1.011600769 1 10.77703246 -6.072860967 0.676038096 0.94626939 0.100867428 0.947785512 0.076592081 0.118125375 0.101272769 0.015988385 0.048776544 8.46E-07 6.072860967 -0.845401962 down AAS(ph)SSSPGS(ph)PVASSPSR ddPTM_HeLa_Curcumin_4h_R1 1 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 2 0 AAS(0.443)S(0.207)S(0.322)S(0.356)PGS(0.646)PVAS(0.026)SPSR 170 0.00016239 35422000 3318 2934.2 3424.4 3599.9 3623.3 4431.7 5617.6 3993.8 3771.1 3783 TRUE FALSE FALSE 3055.376799 3187.819173 3551.311276 3585.004568 3580.094514 3512.515464 5775.214737 5211.491235 3357.419765 3914.458968 0.780536167 0.814370313 0.907229148 0.915836543 0.914582205 0.897318248 1.475354521 1.331343942 0.857697013 1 11.93459721 -4.766736251 24.99972601 0.891958517 1.4033493 0.908721997 0.0655707 30.73453415 145061.5228 0.012415208 0.038912093 1.71E-05 4.766736251 0.511390783 AAS(ph)SSSPGSPVAS(ph)SPSR ddPTM_HeLa_Curcumin_4h_R1 1 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 2 0 AAS(0.316)S(0.348)S(0.327)S(0.079)PGS(0.045)PVAS(0.615)S(0.135)PS(0.135)R 75.682 0.009143 0 740.4 959.51 1104.8 1183.9 960.26 1132 1238.8 997.04 1110.9 978.69 TRUE FALSE FALSE 681.7965587 1042.445769 1145.74486 1179.001335 948.8095267 897.2104397 1273.557394 1301.032906 989.0370493 1012.699405 0.673246726 1.02937334 1.131377045 1.164216479 0.936911311 0.885959284 1.25758679 1.284717756 0.976634374 1 9.983990293 -7.052816805 7.792604234 0.845690275 1.099647383 0.321088042 0.143955816 0.260745535 35.05719907 0.028264099 0.034789803 8.85E-08 7.052816805 0.253957108 ASEAAS(ph)PLPDSPGDKLVIVK ddPTM_HeLa_Curcumin_4h_R1 2 ASEAASPLPDSPGDKLVIVK 20 1 Q68CZ2;Q68CZ2-2 Q68CZ2 TNS3 Tensin-3 1 0 AS(0.01)EAAS(0.99)PLPDSPGDKLVIVK;AS(0.013)EAAS(0.987)PLPDSPGDKLVIVK ; 104.67 0.00015589 135570000 9736.2 6267.7 6262.3 7361.7 4388.5 3996.6 2504.7 2699.4 9969.2 8667.4 TRUE FALSE FALSE 8965.569496 6809.45206 6494.386347 7331.239236 4336.170004 3167.660109 2574.975141 3522.434633 8875.603702 8968.591505 0.999663045 0.759255459 0.72412556 0.817434848 0.483483945 0.353194825 0.287110316 0.392752266 0.989631839 1 13.13066572 -5.943969888 0.639598906 1.007487751 0.26011 0.907437643 0.081059574 0.167363951 0.122760344 0.017375985 0.06215759 1.14E-06 5.943969888 -0.74737775 down AASAPAKES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 AASAPAKESPR 11 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 AASAPAKES(1)PR;AASAPAKES(1)PR;AASAPAKES(1)PR;AASAPAKES(1)PR ;;; 86.262 0.0093477 962211000 28566 27068.8 26711.2 25580.9 27896.6 34848.5 29240.5 18515.4 29018.2 24933.5 TRUE FALSE FALSE 26304.97096 29408.50646 27701.14057 25475.05301 27563.95126 27620.52828 30060.90973 24160.66023 25834.97606 25799.93727 1.019574997 1.139867363 1.07369023 0.987407556 1.068372802 1.070565714 1.165154373 0.936461976 1.001358096 1 14.65507994 -7.492842085 20.90810007 1.008635779 1.066042632 0.147570857 0.062015937 70.05837434 48768.79676 0.010077403 0.011020431 3.21E-08 7.492842085 0.057406853 AASAPAKESPR ddPTM_HeLa_Curcumin_4h_R1 1 AASAPAKESPR 11 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 0 0 112.85 0.0048849 5246300 2163.3 1890.1 2003.2 1903.1 2206.1 2772.9 2191.9 1214.6 2027.2 2264.2 FALSE FALSE TRUE 1992.072522 2053.471822 2077.440354 1895.225476 2179.793698 2197.769283 2253.398815 1584.925949 1804.821232 2342.880781 0.850266278 0.876473032 0.8867034 0.808929542 0.930390362 0.93806279 0.961806863 0.676485957 0.770342753 1 11.19406783 -9.302201264 0.87962763 1.005284674 0.871560934 0 0.104547955 0.66157269 0.859614036 0.060198751 0.013814698 4.99E-10 9.302201264 -0.13372374 AASAPAKGT(ph)PGKGATPAPPGK ddPTM_HeLa_Curcumin_4h_R1 1 AASAPAKGTPGKGATPAPPGK 21 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 AAS(0.063)APAKGT(0.927)PGKGAT(0.01)PAPPGK 73.138 0.0010824 158500000 5985.1 4479.4 4818.3 5554.2 4854.9 8682.1 7114.2 1974.5 7370 5539 TRUE FALSE FALSE 5511.37302 4866.579376 4996.870437 5531.218192 4797.008488 6881.334593 7313.805305 2576.515961 6561.529439 5731.479838 0.961596861 0.849096484 0.871829018 0.965059347 0.836958102 1.200620919 1.276076251 0.449537647 1.144822912 1 12.48469197 -8.132758192 1.608890799 0.99030372 0.94186309 0.038295268 0.216897385 1.880055226 9.859839687 0.04735097 0.039061379 7.37E-09 8.132758192 -0.04844063 AASDGQYENQS(ph)PEATSPR ddPTM_HeLa_Curcumin_4h_R1 2 AASDGQYENQSPEATSPR 18 0 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0;H0Y4U1 A0A087WWW7 TNS1 Tensin-1 1 0 AASDGQYENQS(1)PEATSPR;AASDGQYENQS(1)PEATSPR ; 262.37 1.84E-53 10360100 564.25 717.7 794.47 755.26 613.01 587.5 654.77 385.38 1015.47 768.17 TRUE FALSE FALSE 519.5890171 779.73479 823.9137571 752.1349342 605.7002561 465.6458775 673.141084 502.8805879 904.0754816 794.8638503 0.653683039 0.980966476 1.036547022 0.94624373 0.762017616 0.585818411 0.846863376 0.632662547 1.137396651 1 9.634563957 -5.55453964 7.693574615 0.867862102 0.699222677 0.32368882 0.149156185 0.254997796 50.54619706 0.023284374 0.047036087 2.79E-06 5.55453964 -0.168639425 AASDIAMTELPPTHPIR ddPTM_HeLa_Curcumin_4h_R1 1 AASDIAMTELPPTHPIR 17 0 P62258;P62258-2;K7EM20 P62258 YWHAE 14-3-3 protein epsilon 0 0 77.726 0.0075719 3819400 3587.6 2825.8 2918.4 3137.9 3344.3 4905.7 3400.5 3659.4 4231 3790 FALSE FALSE TRUE 3303.637674 3070.04956 3026.558471 3124.916201 3304.421407 3888.202521 3495.908878 4775.134214 3766.869885 3921.702218 0.84239891 0.78283597 0.77174612 0.796826487 0.842598755 0.991457868 0.891426397 1.217617746 0.9605191 1 11.93726428 -2.889923065 1.387533568 0.889645405 12.66093311 0.601674885 0.082160056 36.08986105 2.358774619 0.014707371 1253.36413 0.001288478 2.889923065 11.77128771 AASDPLLSS(ph)VSPAVSK ddPTM_HeLa_Curcumin_4h_R1 2 AASDPLLSSVSPAVSK 16 0 P19532 P19532 TFE3 Transcription factor E3 1 0 AASDPLLS(0.23)S(0.767)VS(0.003)PAVSK;AASDPLLS(0.298)S(0.64)VS(0.054)PAVS(0.009)K ; 153.94 0.0003221 162858000 10511.3 7308.8 8384.3 9478 9257.3 8322.1 6142.3 3775 9268.8 7262.6 TRUE FALSE FALSE 9679.319514 7940.540105 8695.029534 9438.782547 9146.912744 6596.002651 6314.636407 4925.980122 8252.035829 7514.974809 1.288004253 1.056628972 1.157027103 1.255996565 1.217158138 0.877714539 0.840273796 0.655488574 1.098078974 1 12.87555255 -5.008658848 2.379017691 1.148126911 0.735801384 0.760276351 0.094478322 0.140650806 1.556481963 0.017675708 0.064495347 9.80E-06 5.008658848 -0.412325527 AASDS(ph)NPAGPLR ddPTM_HeLa_Curcumin_4h_R1 1 AASDSNPAGPLR 12 0 Q9BUU2-2;Q9BUU2 Q9BUU2-2 METTL22 Methyltransferase-like protein 22 1 0 AAS(0.015)DS(0.985)NPAGPLR 130.19 0.0024476 26215000 1778.4 1437.1 1343.2 1604.8 1736.2 1957.9 1474.6 2736.1 1564.8 1780.8 TRUE FALSE FALSE 1637.637763 1561.31652 1392.980174 1598.159763 1715.496949 1551.80947 1515.973307 3570.324295 1393.145355 1842.682667 0.888724788 0.847306239 0.755952285 0.867300589 0.930977959 0.842146886 0.822699065 1.937568718 0.756041927 1 10.84759193 -4.258578781 24.99996798 0.907331314 1.93756909 0.934635093 0.08480217 49.64333301 433830.619 0.012142087 0.113317327 5.51E-05 4.258578781 1.030237776 AASEQQADTS(ph)GGDS(ph)PKV ddPTM_HeLa_Curcumin_4h_R1 1 AASEQQADTSGGDSPKV 17 1 U3KQ26 U3KQ26 FOXK1 2 0 AASEQQADT(0.434)S(0.57)GGDS(0.996)PKV 97.352 0.0041148 3764700 2726 2273.2 2616 2811.7 2550.2 2981.3 2697.7 2155 2878.5 2487 TRUE FALSE FALSE 2510.234224 2469.685279 2712.951261 2800.06593 2519.790531 2362.944774 2773.390202 2812.04958 2562.735752 2573.423065 0.975445607 0.959688794 1.054218911 1.088070581 0.979159068 0.91821077 1.077704727 1.092727278 0.995847044 1 11.32947294 -6.75873739 24.99979767 0.985927183 1.031519052 0.196974392 0.051252343 108.6516117 1005274.053 0.008517331 0.011731206 1.74E-07 6.75873739 0.045591869 AASEQQADTSGGDS(ph)PKV ddPTM_HeLa_Curcumin_4h_R1 4 AASEQQADTSGGDSPKV 17 1 U3KQ26 U3KQ26 FOXK1 1 0 AASEQQADTSGGDS(1)PKV;AASEQQADTSGGDS(1)PKV;AASEQQADTSGGDS(1)PKV;AASEQQADTSGGDS(1)PKV ;;; 279.27 1.76E-65 111892000 11856.4 9709.5 9648.6 10508.6 10106.1 12108.1 10678.3 10554.7 10903.3 9446 TRUE FALSE FALSE 10917.95343 10548.74592 10006.1856 10465.1182 9985.591358 9596.743574 10977.90436 13772.77944 9707.235269 9774.247797 1.117012138 1.079238642 1.023729479 1.070682718 1.021622489 0.981839603 1.123145697 1.409088426 0.993143971 1 13.25476996 -4.29113804 3.268179324 1.050537701 1.447469881 0.871421767 0.042689428 0.088547533 1.538939345 0.006975245 0.084831299 5.12E-05 4.29113804 0.39693218 AASGEDSTEEALAAAAAPWEGGPVPGVDRS(ph)PFAK ddPTM_HeLa_Curcumin_4h_R1 2 AASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAK 34 1 Q641Q2;F8W7U3;E7ESD2;Q641Q2-2;A0A087WYF6 Q641Q2 FAM21A WASH complex subunit FAM21A 1 0 AASGEDSTEEALAAAAAPWEGGPVPGVDRS(1)PFAK;AASGEDSTEEALAAAAAPWEGGPVPGVDRS(1)PFAK ; 108.85 1.78E-14 61383000 2508.82 2128.38 2301.06 2413.31 2418.26 2821.05 1975.13 1480.6 2826.6 2461.98 TRUE FALSE FALSE 2310.24425 2312.347683 2386.339308 2403.324363 2389.423829 2235.93243 2030.546832 1932.028124 2516.529052 2547.533622 0.906855254 0.907680929 0.936725344 0.943392598 0.937936131 0.877685151 0.797063801 0.75839161 0.987829574 1 11.31488547 -2.603564429 0.403431021 0.959588298 4.49E-12 0.842724809 0.028966783 6.471543816 0.255352384 0.009509074 4.022961942 0.002491355 2.603564429 -0.959588298 AASGEDSTEEALAAAAAPWEGGPVPGVDT(ph)SPFAK ddPTM_HeLa_Curcumin_4h_R1 1 AASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAK 34 0 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1-5;Q5SRD0 A0A0A0MR88 FAM21C;FAM21D WASH complex subunit FAM21C;Putative WASH complex subunit FAM21 1 0 AASGEDSTEEALAAAAAPWEGGPVPGVDT(0.595)S(0.405)PFAK 116.52 5.15E-18 13592000 4947.6 3770.4 4158.9 4365.6 4119.3 4851.7 3304 2902.4 5269.3 3921.8 TRUE FALSE FALSE 4555.992239 4096.296575 4313.032493 4347.536304 4070.180038 3845.40273 3396.701348 3787.328399 4691.270973 4058.082258 1.122695882 1.009416841 1.0628253 1.071327792 1.002981157 0.947591124 0.837021315 0.933280342 1.156031513 1 11.98658239 -5.253226171 2.041270725 1.056236568 0.88562041 0.675304069 0.05104362 0.15229231 1.215615249 0.007522058 0.023543419 5.58E-06 5.253226171 -0.170616158 S(ph)KSEEAHAEDSVMDHHFR ddPTM_HeLa_Curcumin_4h_R1 2 SKSEEAHAEDSVMDHHFR 18 1 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 0 S(0.548)KS(0.452)EEAHAEDSVMDHHFR;S(0.844)KS(0.156)EEAHAEDSVMDHHFR ; 90.259 0.00079017 43134000 3463.8 2275.13 2127.73 2444.73 2971.2 14715.6 17303.3 14725.1 3639.2 2547.33 TRUE FALSE FALSE 3189.636575 2471.782099 2206.585546 2434.614355 2935.770381 11663.41868 17788.78403 19214.7152 3239.988865 2635.849528 1.210098126 0.937755389 0.837143973 0.923654529 1.113785271 4.42491825 6.748785862 7.289761802 1.229200996 1 11.3640523 -5.022419997 2.115104484 1.037460719 7.20837562 0.994010648 0.189234779 0.018387702 0.15840219 0.031402034 0.120850315 9.50E-06 5.022419997 6.170914901 up AASIFGGAKPVDTAAR ddPTM_HeLa_Curcumin_4h_R1 2 AASIFGGAKPVDTAAR 16 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 0 ; ; 75.316 0.0054005 6061800 5581.2 4894.1 4397.8 4424.6 5131 7225.4 5239.6 5444.8 5419.6 4630.8 FALSE FALSE TRUE 5139.442131 5317.124196 4560.786337 4406.292178 5069.816176 5726.770593 5386.609074 7104.894455 4825.083439 4791.719955 1.072567299 1.109648361 0.951805694 0.919563793 1.058036827 1.195138832 1.124149392 1.482744092 1.006962737 1 12.22632788 -1.000009642 0.817529354 1.028706647 128.3095351 0.804682075 0.067210774 176.6952395 0.537182026 0.011099506 41744.26281 0.09999778 1.000009642 127.2808284 AASITSEVFNK ddPTM_HeLa_Curcumin_4h_R1 1 AASITSEVFNK 11 0 Q9Y5B9 Q9Y5B9 SUPT16H FACT complex subunit SPT16 0 0 157.95 1.68E-07 1042400 670.45 516.39 527.25 699.37 676.01 810.36 834.27 467.85 609.17 665.81 FALSE FALSE TRUE 617.383175 561.0244506 546.7903488 696.4761922 667.9490223 642.2822014 857.6773709 610.4953113 542.3455751 688.9468479 0.896125988 0.814321819 0.793661152 1.010928774 0.96952185 0.932266696 1.244910799 0.886128318 0.787209604 1 9.428248873 AASLNYLNQPS(ph)AAPLQVSR ddPTM_HeLa_Curcumin_4h_R1 1 AASLNYLNQPSAAPLQVSR 19 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 0 AAS(0.015)LNYLNQPS(0.866)AAPLQVS(0.12)R 185.59 1.11E-07 158140000 1450.7 881.68 1227.6 1225.6 1075.3 1633.5 1381.5 1217.9 1316.2 1418 TRUE FALSE FALSE 1335.875564 957.8884905 1273.095936 1220.528792 1062.47775 1294.693687 1420.261172 1589.232103 1171.816153 1467.275394 0.910446375 0.652834835 0.867659841 0.831833476 0.724116109 0.882379471 0.967958147 1.083117804 0.798634092 1 10.51892396 -8.061617135 1.569369764 0.976755482 0.857160858 0 0.126071012 0.451498697 2.269990157 0.027291809 0.02314015 8.68E-09 8.061617135 -0.119594624 AASLTEDRDR ddPTM_HeLa_Curcumin_4h_R1 2 AASLTEDRDR 10 1 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 0 ; ; 137.05 0.0016584 36963000 3868.8 2860.9 3312 3330.6 3346.7 3822.1 2957.8 2484.79 3467.9 3181.6 FALSE FALSE TRUE 3562.580398 3108.183448 3434.745634 3316.81886 3306.792788 3029.353376 3040.787907 3242.391032 3087.480046 3292.160363 1.082140602 0.944116661 1.043310548 1.007490065 1.004444627 0.920171876 0.923645136 0.984882471 0.937827963 1 11.6848189 -5.480116313 2.684862084 1.030308502 0.941210343 0.102369383 0.04813177 0.195599734 2.784698969 0.006448869 0.015524977 3.31E-06 5.480116313 -0.089098159 AASPAKPS(ph)SLDLVPNLPK ddPTM_HeLa_Curcumin_4h_R1 1 AASPAKPSSLDLVPNLPK 18 1 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 0 AAS(0.426)PAKPS(0.565)S(0.009)LDLVPNLPK 106.73 0.00040927 654220000 7790.3 5852.5 6406.4 6104.6 6389.5 6530.1 4747.9 2985.4 7102.5 5586.2 TRUE FALSE FALSE 7173.689535 6358.364022 6643.82682 6079.340783 6313.309386 5175.683651 4881.113296 3895.634717 6323.37352 5780.320034 1.241054041 1.100002073 1.149387366 1.051730829 1.092207585 0.895397421 0.844436513 0.673947929 1.093948688 1 12.49693366 -4.739197969 0.997356791 1.117496037 0.619415703 0.843096286 0.062613165 0.406940311 0.496994536 0.014343498 0.180472526 1.82E-05 4.739197969 -0.498080333 AASPPS(ph)YTLDLGESQLAPPPSK ddPTM_HeLa_Curcumin_4h_R1 1 AASPPSYTLDLGESQLAPPPSK 22 0 Q9ULQ0-2;Q9ULQ0 Q9ULQ0-2 STRIP2 Striatin-interacting protein 2 1 0 AAS(0.108)PPS(0.891)YT(0.001)LDLGESQLAPPPSK 155.91 6.36E-07 4098600 2815.1 2351.8 2052.5 2382.3 2271.8 2642.1 2148 1968.6 2601.4 2245.2 TRUE FALSE FALSE 2592.281865 2555.079113 2128.567456 2372.442674 2244.710269 2094.098677 2208.267099 2568.817078 2316.032928 2323.220533 1.115813944 1.099800504 0.91621412 1.021187029 0.96620628 0.901377483 0.950519793 1.105713832 0.996906189 1 11.18191039 -6.768563481 24.99973948 1.059601312 0.97377028 0.250591523 0.064083949 168.3911368 590913.7039 0.011009097 0.014639228 1.70E-07 6.768563481 -0.085831032 AASPSPQS(ph)VR ddPTM_HeLa_Curcumin_4h_R1 1 AASPSPQSVR 10 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 AAS(0.173)PS(0.033)PQS(0.794)VR 92.295 0.01769 11225000 2026.9 1970.3 1848.2 1933.6 1549.5 2316.3 1884.6 1874.9 2084 2039.1 TRUE FALSE FALSE 1866.468726 2140.603953 1916.695918 1925.599276 1531.023225 1835.87327 1937.476804 2446.548379 1855.390414 2109.958573 0.884599703 1.014524162 0.908404526 0.91262421 0.72561767 0.870099202 0.918253481 1.159524367 0.879349214 1 11.04299896 -9.473681007 1.017681112 1.003944851 0.914307909 0 0.11067856 1.302840942 2.233057575 0.090544133 0.01858321 3.36E-10 9.473681007 -0.089636942 AASPYSQRPAS(ph)PTAIR ddPTM_HeLa_Curcumin_4h_R1 1 AASPYSQRPASPTAIR 16 1 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 0 AASPYS(0.001)QRPAS(0.971)PT(0.028)AIR 142.4 0.0036806 13097000 950.97 836.25 1024.4 1060.4 1122.9 1268.4 933 549.39 1192.6 1146.4 TRUE FALSE FALSE 875.699721 908.5317237 1062.365165 1056.012346 1109.510151 1005.319542 959.177469 716.8964819 1061.774764 1186.237315 0.7382163 0.765893732 0.895575575 0.890220138 0.935318875 0.847486021 0.808588178 0.604344909 0.895077866 1 10.21217694 -9.460729226 1.188981788 1.000296076 0.811948853 0.225547742 0.094667852 0.429472934 1.083421953 0.066220325 0.016269573 3.46E-10 9.460729226 -0.188347223 AASSDQLRDNS(ph)PPPAFKPEPPK ddPTM_HeLa_Curcumin_4h_R1 1 AASSDQLRDNSPPPAFKPEPPK 22 2 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 AAS(0.027)S(0.025)DQLRDNS(0.948)PPPAFKPEPPK 69.284 0.001864 10332000 1680 1361.9 1536.4 1530.7 1555.9 1490.5 982.64 1188.8 1489.1 1626 TRUE FALSE FALSE 1547.026227 1479.616567 1593.340336 1524.366369 1537.346909 1181.353499 1010.210234 1551.259647 1325.749456 1682.503379 0.919478823 0.879413727 0.947005727 0.906010881 0.913725897 0.702140342 0.600420924 0.921994967 0.787962433 1 10.71639369 -5.338709671 4.334821881 0.947990707 0.727332105 0.340100439 0.095211934 0.111376927 3.918075607 0.011390653 0.026736472 4.58E-06 5.338709671 -0.220658602 AASSLNLS(ph)NGETESVK ddPTM_HeLa_Curcumin_4h_R1 2 AASSLNLSNGETESVK 16 0 O95819-3;E7EX83;G5E948;C9J840;H7C360;E7ENQ1;H7C0P6;G3XAA2;A0A0D9SG62;A0A0D9SEY1;O95819-4;O95819-2;O95819;O95819-5;O95819-6;E7EN19 O95819-3 MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 1 0 AASS(0.005)LNLS(0.995)NGET(0.001)ESVK;AASSLNLS(0.999)NGETESVK ; 253.36 4.10E-40 41454000 5492.6 5088.6 5048.5 5115.8 5043.6 7050.6 4850.9 2520.3 5697.2 4532.9 TRUE FALSE FALSE 5057.854914 5528.43591 5235.601851 5094.632175 4983.458364 5588.226083 4987.003198 3288.727868 5072.231414 4690.417938 1.07833779 1.178665949 1.116233547 1.086178725 1.0624764 1.191413251 1.063232161 0.701158812 1.081402869 1 12.19550076 -4.262085254 7.532663308 1.069130383 0.697264078 0.79476125 0.058756322 0.040628318 22.65547576 0.00973464 0.077197099 5.47E-05 4.262085254 -0.371866305 ADSGPTQPPLSLS(ph)PAPETKRPGQAAK ddPTM_HeLa_Curcumin_4h_R1 1 ADSGPTQPPLSLSPAPETKRPGQAAK 26 2 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;X6RGP5;A0A0C4DH09;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 ADS(0.002)GPT(0.004)QPPLS(0.218)LS(0.775)PAPET(0.001)KRPGQAAK 58.776 0.0014167 83679000 4254.5 2694.1 2831.3 2935 1536.5 2984.2 1462.7 707.85 3963.1 3718.4 TRUE FALSE FALSE 3917.751836 2926.965999 2936.230469 2922.855748 1518.178241 2365.243281 1503.739425 923.6702065 3528.357845 3847.614123 1.018228884 0.760722335 0.763130183 0.759654075 0.394576533 0.614729857 0.390823866 0.240063108 0.917024871 1 11.9097484 -5.808001166 0.504356005 1.027609532 0.232478503 0.848161274 0.099749459 0.300944082 0.122430758 0.023842619 0.11042299 1.56E-06 5.808001166 -0.795131028 down S(ph)FEVEEVETPNSTPPR ddPTM_HeLa_Curcumin_4h_R1 6 SFEVEEVETPNSTPPR 16 0 Q9UHD8;Q9UHD8-5;Q9UHD8-2;Q9UHD8-7;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 SEPT9 Septin-9 1 0 S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR;S(1)FEVEEVETPNSTPPR ;;;;; 320.06 3.38E-112 387855200 6849.25 5369.5 6071.86 5939.1 5757.62 11469.6 12570.06 8791.36 6670.3 5432.92 TRUE FALSE FALSE 6307.124635 5833.615654 6296.888473 5914.525578 5688.964142 9090.675671 12922.74205 11471.80519 5938.584778 5621.713566 1.12192209 1.037693505 1.120101264 1.0520859 1.011962647 1.617064898 2.298719403 2.040624279 1.056365592 1 12.45679423 -5.017559256 2.937246157 1.05934044 2.168452477 0.969102145 0.079789353 0.028943818 0.500772152 0.011531362 0.037842854 9.60E-06 5.017559256 1.109112037 up AASSS(ph)SPGS(ph)PVASSPSR ddPTM_HeLa_Curcumin_4h_R1 1 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 2 0 AAS(0.029)S(0.15)S(0.795)S(0.377)PGS(0.436)PVAS(0.165)S(0.044)PS(0.004)R 88.319 0.012262 40192000 2616.1 3231.6 3125.3 3664.4 3201.5 4468.6 5034.5 3891.9 3678.7 3644.6 TRUE FALSE FALSE 2409.032925 3510.925104 3241.126367 3649.237684 3163.324203 3541.761988 5175.75452 5078.522394 3275.155814 3771.249579 0.638789047 0.930971295 0.859430356 0.967646826 0.838800015 0.93914813 1.372424289 1.346641819 0.868453743 1 11.88082691 -4.81667618 3.936518368 0.848319063 1.368457959 0.801483899 0.095169646 0.088015146 2.739087529 0.019513297 0.068865375 1.53E-05 4.81667618 0.520138897 AASSS(ph)SPGSPVASS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 2 0 AAS(0.019)S(0.142)S(0.836)S(0.003)PGS(0.001)PVAS(0.291)S(0.648)PS(0.06)R;AAS(0.002)S(0.407)S(0.589)S(0.001)PGSPVAS(0.311)S(0.687)PS(0.002)R ; 139.12 0.00084915 8686100 3759.5 3675.9 3743.6 3917.8 3934.6 4662.7 4104.9 3711.1 3950.6 4788.6 TRUE FALSE FALSE 3461.931608 3993.628417 3882.341109 3901.589182 3887.682465 3695.603461 4220.072446 4842.597306 3517.229064 4955.003494 0.698673899 0.805978931 0.783519349 0.787403921 0.784597321 0.745832665 0.851679005 0.97731461 0.709833821 1 12.27467036 -9.495311065 1.238758754 1.000085426 0.790842177 0 0.1130396 0.296106684 0.812600685 0.052358414 0.012706956 3.20E-10 9.495311065 -0.209243249 AASSS(ph)SPGSPVASSPSR ddPTM_HeLa_Curcumin_4h_R1 1 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 0 AAS(0.346)S(0.063)S(0.546)S(0.015)PGS(0.03)PVASSPSR 244 1.37E-30 35345000 3864.1 3386.5 3743.7 4012.2 3615.3 5189.6 4364.2 3798.1 3999.1 3942.8 TRUE FALSE FALSE 3558.252408 3679.21397 3882.444815 3995.598579 3572.189909 4113.218461 4486.647706 4956.123206 3560.408735 4079.812007 0.872160875 0.901809682 0.951623459 0.979358503 0.875577086 1.008188234 1.099719227 1.214792054 0.872689411 1 11.99428696 -4.620419059 1.735788136 0.935532739 1.22614719 0.815982348 0.045309952 0.186583209 0.881052591 0.007814884 0.071070794 2.40E-05 4.620419059 0.290614451 AASSSSPGS(ph)PVASSPSR ddPTM_HeLa_Curcumin_4h_R1 1 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 0 AASSS(0.005)S(0.149)PGS(0.842)PVAS(0.003)SPSR 172.32 4.72E-05 34599000 3607.8 2862.3 3349.1 3259.8 4027.9 4865 3790 3586.8 3619.4 3652.4 TRUE FALSE FALSE 3322.238823 3109.704458 3473.220592 3246.311811 3979.869923 3855.94416 3896.3372 4680.398808 3222.360875 3779.320628 0.879057151 0.822821021 0.919006598 0.858967029 1.053064906 1.02027442 1.03096233 1.238423322 0.852629663 1 11.8839112 -3.295303735 0.722861727 0.928485729 2.197481887 0.698268044 0.06606933 4.683147971 0.620205323 0.012021039 6.733686002 0.000506636 3.295303735 1.268996158 AIKVEQATKPS(ph)FESGR ddPTM_HeLa_Curcumin_4h_R1 1 AIKVEQATKPSFESGR 16 2 P38159;P38159-2;H0Y6E7;H3BT71 P38159 RBMX "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed" 1 0 AIKVEQAT(0.005)KPS(0.963)FES(0.032)GR 76.329 0.011933 63245000 1909.5 1338.6 1594.8 1686.3 1346.6 2083.7 1316.9 765 2301.9 2082.1 TRUE FALSE FALSE 1758.36106 1454.302619 1653.904691 1679.322537 1330.542674 1651.517132 1353.84867 998.2449784 2049.387329 2154.45282 0.816152038 0.675021799 0.767668094 0.779465914 0.617578005 0.766559897 0.628395599 0.463340375 0.951233329 1 11.07310579 -5.766607562 0.084429203 1.389989048 7.70E-17 0.782269925 0.070584707 11.79422874 0.304625306 1.787677536 3.265290079 1.71E-06 5.766607562 -1.389989048 down AASVAAATT(ph)SPTPR ddPTM_HeLa_Curcumin_4h_R1 2 AASVAAATTSPTPR 14 0 Q9Y2D9 Q9Y2D9 ZNF652 Zinc finger protein 652 1 0 AASVAAAT(0.091)T(0.765)S(0.143)PT(0.001)PR;AASVAAAT(0.089)T(0.854)S(0.057)PTPR ; 149.57 0.0015178 37000000 10244.7 7760.3 9285.8 9334.4 9872.8 11947.2 9182.8 5713.8 10741.4 10551 TRUE FALSE FALSE 9433.821185 8431.065753 9629.939917 9295.776726 9755.073308 9469.216047 9440.444654 7455.911317 9563.095294 10917.64646 0.864089272 0.772242056 0.882052734 0.851445113 0.893514306 0.867331258 0.864695947 0.682922949 0.875930112 1 13.41437427 -13.52287875 0.166575535 1.662271164 0.795266186 0.166036683 0.071018143 34.06534629 0.373200516 7.277689036 0.10034906 3.00E-14 13.52287875 -0.867004978 AATAARPPAPPPAPQPPS(ph)PT(ph)PSPPRPTLAR ddPTM_HeLa_Curcumin_4h_R1 1 AATAARPPAPPPAPQPPSPTPSPPRPTLAR 30 2 Q96B36-3;Q96B36;H9KV91 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 2 0 AATAARPPAPPPAPQPPS(0.847)PT(0.668)PS(0.48)PPRPT(0.005)LAR 115.2 3.85E-12 142320000 1723.5 1519.7 1688.5 1850.5 1885.5 2116 1506.1 1429.9 1822.3 1630.1 TRUE FALSE FALSE 1587.083156 1651.056096 1751.077295 1842.843121 1863.016644 1677.117748 1548.357113 1865.869928 1622.398249 1686.745854 0.940914218 0.978841058 1.03813938 1.092543442 1.104503467 0.994291905 0.917955191 1.106195058 0.961851037 1 10.7200269 -6.778711071 5.512782607 0.971598365 1.039756813 0.291331472 0.054910278 0.194049563 17.49700057 0.00936625 0.012687155 1.66E-07 6.778711071 0.068158448 AATAARPPAPPPAPQPPS(ph)PTPSPPRPTLAR ddPTM_HeLa_Curcumin_4h_R1 2 AATAARPPAPPPAPQPPSPTPSPPRPTLAR 30 2 Q96B36-3;Q96B36;H9KV91 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 0 AATAARPPAPPPAPQPPS(0.599)PT(0.149)PS(0.104)PPRPT(0.149)LAR;AATAARPPAPPPAPQPPS(0.418)PT(0.124)PS(0.041)PPRPT(0.418)LAR ; 80.68 1.71E-06 204432000 964.48 851.46 1057.2 1022.45 914.95 1089.89 765.26 711.52 1053 971.95 TRUE FALSE FALSE 888.1403903 925.0564084 1096.380762 1018.219373 904.0398188 863.8345284 786.731136 928.4591726 937.4885345 1005.72519 0.883084563 0.919790433 1.090139506 1.012423058 0.898893483 0.858917065 0.782252591 0.923173827 0.932151788 1 9.974020434 -5.495980971 3.979645588 0.957843735 0.849696929 0.404519215 0.063420323 0.208712106 7.27050918 0.010626078 0.02378495 3.19E-06 5.495980971 -0.108146806 AATAARPPAPPPAPQPPSPT(ph)PS(ph)PPRPTLAR ddPTM_HeLa_Curcumin_4h_R1 1 AATAARPPAPPPAPQPPSPTPSPPRPTLAR 30 2 Q96B36-3;Q96B36;H9KV91 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 2 0 AATAARPPAPPPAPQPPS(0.035)PT(0.976)PS(0.977)PPRPT(0.012)LAR 76.98 0.0001622 133060000 920.65 888.8 1003.2 899.45 941.1 850.74 1077.7 1079.6 950.98 623.13 TRUE FALSE FALSE 847.779581 965.6239116 1040.379475 895.7283142 929.8779972 674.2869342 1107.937362 1408.76507 846.6598732 644.7837211 1.31482783 1.497593503 1.613532477 1.389191887 1.442154891 1.045756759 1.71830852 2.184864512 1.313091267 1 9.33267151 -1 0.106338082 0.775864163 3.814411325 0.37768809 0.255338904 73.60672733 0.552068013 1.686204618 32.88149086 0.1 1 3.038547163 TETQEKNPLPS(ph)KETIEQEK ddPTM_HeLa_Curcumin_4h_R1 1 TETQEKNPLPSKETIEQEK 19 2 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 1 0 T(0.045)ET(0.146)QEKNPLPS(0.708)KET(0.101)IEQEK 65.287 0.010234 19899000 1187.4 789.95 866.13 739.77 1158 2119.1 3185.7 1765 1093.1 708.52 TRUE FALSE FALSE 1093.416037 858.2297581 898.2295397 736.7090278 1144.191606 1679.574773 3275.082168 2303.140375 973.1896648 733.1410173 1.491412991 1.170620301 1.225179766 1.004866745 1.560670566 2.29093003 4.467192656 3.141469814 1.327424932 1 9.517946912 -5.01614401 2.779444217 1.231992762 3.80248311 0.882301022 0.36763049 0.056321764 0.865441456 0.049914689 0.167758403 9.64E-06 5.01614401 2.570490348 up AATEALGEKSPDS(ph)ATVSGYDIMK ddPTM_HeLa_Curcumin_4h_R1 1 AATEALGEKSPDSATVSGYDIMK 23 1 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;H0Y7E2;K7EL39;J3QRL2;H7C3G6 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 AATEALGEKS(0.39)PDS(0.571)AT(0.033)VS(0.005)GY(0.001)DIMK 88.09 0.00011742 109410000 1636.5 1280.9 1468.1 1537 1192.1 1754 1501.6 2627.6 1386.2 1638.5 TRUE FALSE FALSE 1506.969298 1391.615288 1522.509077 1530.640301 1177.884986 1390.200628 1543.730855 3428.743144 1234.137328 1695.437753 0.88883788 0.820799989 0.898003524 0.902799468 0.694737972 0.819965596 0.910520514 2.022335021 0.727916626 1 10.7274421 -4.261494802 8.830148528 0.904412904 2.027821059 0.92452863 0.099328025 0.016105792 22.93565637 0.013733789 0.107432893 5.48E-05 4.261494802 1.123408155 ADIKSPS(ph)LDVTVPEAELNLETPEISVGGK ddPTM_HeLa_Curcumin_4h_R1 1 ADIKSPSLDVTVPEAELNLETPEISVGGK 29 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 ADIKS(0.1)PS(0.585)LDVT(0.315)VPEAELNLETPEISVGGK 68.527 0.00011021 138330000 6924 4360.1 5355.2 5773.9 4954.5 12192 16268 8731.6 6562.3 4893.2 TRUE FALSE FALSE 6375.958094 4736.967616 5553.668423 5750.009132 4895.420823 9663.241768 16724.4363 11393.82464 5842.432108 5063.238336 1.259264856 0.935560861 1.096860952 1.135638647 0.966855696 1.908510152 3.303110616 2.250303835 1.153892375 1 12.30584468 -5.013073052 3.880095676 1.104770101 2.771337379 0.873085646 0.259522809 0.04547211 1.528637205 0.033393891 0.100852488 9.70E-06 5.013073052 1.666567278 up YGS(ph)FEEAEASYPILNR ddPTM_HeLa_Curcumin_4h_R1 2 YGSFEEAEASYPILNR 16 0 O95425-3;A0A6I8PIX7;O95425-2;O95425;O95425-4 O95425-3 SVIL Supervillin 1 0 YGS(1)FEEAEASYPILNR;YGS(0.695)FEEAEAS(0.305)YPILNR ; 200.63 3.72E-09 23323700 1470.66 857.1 812.97 928.13 899.57 2873.2 4060.6 2370.9 1017.1 866.4 TRUE FALSE FALSE 1354.255709 931.1839048 843.0993834 924.289644 888.8432153 2277.265932 4174.529507 3093.776496 905.5266747 896.5073355 1.510590773 1.038679627 0.940426642 1.030989494 0.991451135 2.54015315 4.656436531 3.450921563 1.01006053 1 9.808171578 -5.006315235 3.44824401 1.181787742 4.038163413 0.925446005 0.338192118 0.042259561 1.059889607 0.048675634 0.152955936 9.86E-06 5.006315235 2.856375671 up AATESVPCS(ph)PSPLAGEIR ddPTM_HeLa_Curcumin_4h_R1 1 AATESVPCSPSPLAGEIR 18 0 J3QKZ5;J9JIE4;J3QS16;Q8N9M1-2;Q8N9M1 J3QKZ5 C19orf47 Uncharacterized protein C19orf47 1 0 AATES(0.018)VPCS(0.976)PS(0.006)PLAGEIR 120.39 0.0010671 0 1872.9 1309.7 1045.1 1280.5 1624.7 2125 1894.9 1864.4 1612.8 1382.6 TRUE FALSE FALSE 1724.657989 1422.904632 1083.832325 1275.20163 1605.326514 1684.251046 1948.065794 2432.846977 1435.879875 1430.645247 1.205510585 0.994589424 0.757582865 0.891347197 1.122099638 1.177266726 1.361669357 1.700524279 1.003658928 1 10.48245026 -4.387523297 1.338318007 1.051208581 1.881972463 0.764416645 0.122143403 0.494355387 0.9035877 0.022055221 0.520024552 4.10E-05 4.387523297 0.830763881 AATS(ph)PGVGQSAPGTR ddPTM_HeLa_Curcumin_4h_R1 2 AATSPGVGQSAPGTR 15 0 Q6IE81;Q6IE81-2 Q6IE81 JADE1 Protein Jade-1 1 0 AAT(0.039)S(0.961)PGVGQSAPGTR;AAT(0.049)S(0.95)PGVGQS(0.001)APGTR ; 135.86 0.00061334 30197000 5948 5514.2 6335 6409.9 6362.4 7809.4 6131.6 2730.4 6054.7 5220.1 TRUE FALSE FALSE 5477.209524 5990.822877 6569.780673 6383.377532 6286.532535 6189.64241 6303.636194 3562.886391 5390.514558 5401.498086 1.014016748 1.109103953 1.216288624 1.181779097 1.163849813 1.145912173 1.167016278 0.659610785 0.997966577 1 12.39914387 -7.277180382 5.951063591 1.006384909 1.108038777 0.059950426 0.150469973 0.312230951 43.88238794 0.024450723 0.028523464 5.28E-08 7.277180382 0.101653868 AATSEEPTGFSVDSNLLGS(ph)LSPK ddPTM_HeLa_Curcumin_4h_R1 1 AATSEEPTGFSVDSNLLGSLSPK 23 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 0 AATSEEPTGFSVDS(0.007)NLLGS(0.675)LS(0.318)PK 85.407 0.00017141 4198500 3130.6 2475.4 2435.7 2623.4 2299.7 3153 2295.5 1774.2 3007.9 2772.3 TRUE FALSE FALSE 2882.809707 2689.362546 2525.969185 2612.545066 2272.277579 2499.032258 2359.905552 2315.145413 2677.940895 2868.637219 1.004940495 0.937505282 0.880546752 0.910726895 0.792110471 0.871156604 0.822657371 0.807054094 0.933523723 1 11.48614981 -6.635999375 0.955486275 1.004975355 0.826687002 0.742521475 0.036227037 0.112116101 0.204593117 0.00518106 0.008792586 2.31E-07 6.635999375 -0.178288354 AATSEEPTGFSVDSNLLGSLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 AATSEEPTGFSVDSNLLGSLSPK 23 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 0 AATSEEPTGFSVDS(0.02)NLLGS(0.097)LS(0.883)PK 85.002 0.00017814 4237000 2066.4 1408 1529.3 1664.8 1629.4 2243.9 1680.5 972.59 1809 1770.5 TRUE FALSE FALSE 1902.84226 1529.701246 1585.977203 1657.911499 1609.970469 1778.489846 1727.650307 1269.128214 1610.557226 1832.024743 1.038655327 0.834978486 0.865696388 0.904961303 0.878792972 0.970778289 0.943027824 0.692746219 0.87911325 1 10.83922327 -7.267200553 24.93488251 1.018253907 0.878315431 0.179474394 0.083684 289.892728 1254680.245 0.011678055 0.013543915 5.41E-08 7.267200553 -0.139938476 AATTATPAATTS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 AATTATPAATTSPK 14 0 A0A087X055;Q92766;Q92766-2;Q92766-5;Q92766-3 A0A087X055 RREB1 Ras-responsive element-binding protein 1 1 0 AATTATPAAT(0.001)T(0.089)S(0.91)PK 166.62 0.00021262 15530000 5658.9 3628.1 5968.9 6217.3 7209.4 7157.5 6550.3 3275.2 6451.3 4720.7 TRUE FALSE FALSE 5210.992094 3941.696798 6190.112685 6191.57446 7123.432614 5672.953818 6734.083789 4273.793403 5743.60853 4884.743974 1.066789195 0.806940306 1.267233803 1.267533057 1.458302145 1.161361547 1.378595035 0.874926798 1.175825911 1 12.25406723 -6.721656174 24.99857459 1.015575577 1.249529688 0.294285694 0.167647453 125.9761459 79159.33715 0.023290111 0.03293692 1.90E-07 6.721656174 0.233954111 AAVAGEDGR ddPTM_HeLa_Curcumin_4h_R1 1 AAVAGEDGR 9 0 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;G3V576;G3V555;G3V575;B7ZW38;A0A0G2JPF8;P0DMR1;B4DSU6;G3V251;G3V3K6;G3V5X6;A0A0G2JNQ3;O60812;B2RXH8 P07910;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL1;HNRNPCL2 Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoprotein C-like 1;Heterogeneous nuclear ribonucleoprotein C-like 2 0 0 94.114 0.0161 992870 1006.3 2694.6 1053.1 992.81 824.6 1038.4 738.04 606.15 568.05 1003.9 FALSE FALSE TRUE 926.6502932 2927.509217 1092.128812 988.7020153 814.7671836 823.0241348 758.7474161 790.9623446 505.7363362 1038.78545 0.892051668 2.818203909 1.051351665 0.951786546 0.784345972 0.792294631 0.730417832 0.761429941 0.486853504 1 10.020682 -5.980048011 2.998550551 1.122093693 0.766928675 0.116563438 0.579234773 0.575073565 10.60681821 0.087917227 0.163581942 1.05E-06 5.980048011 -0.355165018 AAVEEGIVLGGGCALLR ddPTM_HeLa_Curcumin_4h_R1 1 AAVEEGIVLGGGCALLR 17 0 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 163.45 0.00069438 652630 331.32 173.25 187.71 252.25 285.18 210.67 246.58 213.84 165.98 62.736 FALSE FALSE TRUE 305.0956724 188.224958 194.6666977 251.2062563 281.7794148 166.9746673 253.4983712 279.0388316 147.7724093 64.91607133 4.699848068 2.899512465 2.998744282 3.869708243 4.340672641 2.572162237 3.905017139 4.298455311 2.276360942 1 6.020503787 -9.442619993 1.101142487 0.955581434 3.742609331 0.524720897 0.750371663 0.237508518 0.501768129 0.52267695 0.122168248 3.61E-10 9.442619993 2.787027898 AAVELEEPEDAR ddPTM_HeLa_Curcumin_4h_R1 2 AAVELEEPEDAR 12 0 O94906-2;O94906 O94906-2 PRPF6 Pre-mRNA-processing factor 6 0 0 ; ; 158.47 0.0022319 14385900 3478.4 2988.3 3262.5 3574.7 3412.6 3711.4 3165.4 1753.4 3161.3 3083.3 FALSE FALSE TRUE 3203.08097 3246.595336 3383.41112 3559.908839 3371.906974 2941.613804 3254.212605 2288.003588 2814.513299 3190.444445 1.003960741 1.017599708 1.060482694 1.115803425 1.056876881 0.92200753 1.019987234 0.717142589 0.882169662 1 11.6395417 -3.776251077 1.694407641 1.016138691 2.69E-16 0.635957978 0.065219521 1.729387277 1.540314159 0.007384142 4.316322458 0.000167397 3.776251077 -1.016138691 AAVGEEKDINTFVGT(ph)PVEK ddPTM_HeLa_Curcumin_4h_R1 2 AAVGEEKDINTFVGTPVEK 19 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 AAVGEEKDINTFVGT(1)PVEK;AAVGEEKDINTFVGT(1)PVEK ; 145.04 0.00011469 49419000 5801.7 3815.6 4748.5 6192.9 6267.1 13005.3 12297 2944.1 7493.8 4633.7 TRUE FALSE FALSE 5342.489323 4145.403462 4924.483587 6167.275421 6192.368926 10307.85418 12642.02072 3841.742537 6671.748889 4794.72073 1.114244108 0.864576624 1.027063695 1.28626374 1.29149731 2.149834111 2.636654236 0.801244275 1.391478099 1 12.22723107 -5.451042597 3.265167965 1.054633087 1.934730529 0.343644539 0.452758656 0.162487899 3.357566647 0.058365947 0.137281583 3.54E-06 5.451042597 0.880097442 AAVGEEKDINTFVGT(ph)PVEKLDLLGNLPGSK ddPTM_HeLa_Curcumin_4h_R1 2 AAVGEEKDINTFVGTPVEKLDLLGNLPGSK 30 2 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 AAVGEEKDINT(0.006)FVGT(0.994)PVEKLDLLGNLPGSK;AAVGEEKDINT(0.011)FVGT(0.989)PVEKLDLLGNLPGSK ; 65.836 0.00013426 52484000 2863.6 1607.64 2151.51 2942.34 1787.93 5155.3 3911.6 1599.94 4269.1 2687.63 TRUE FALSE FALSE 2636.943038 1746.597238 2231.246853 2930.165377 1766.610102 4086.032668 4021.348968 2087.754341 3800.790411 2781.024942 0.948191078 0.628040839 0.802310982 1.053627866 0.635237058 1.469254233 1.44599529 0.750713994 1.366686919 1 11.44140097 -5.254770998 24.98750842 0.921328256 1.244388567 0.205258104 0.271976781 510.3627706 1912405.187 0.031692996 0.078794472 5.56E-06 5.254770998 0.323060311 AAVGQES(ph)PGGLEAGNAK ddPTM_HeLa_Curcumin_4h_R1 2 AAVGQESPGGLEAGNAK 17 0 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 0 AAVGQES(1)PGGLEAGNAK;AAVGQES(1)PGGLEAGNAK ; 220.64 8.75E-16 349330000 6952.3 5921.9 6274.7 7184.2 6282.5 8365.7 6252.1 3251.5 7796.9 6696.4 TRUE FALSE FALSE 6402.018119 6433.762649 6507.245902 7154.473684 6207.585291 6630.559519 6427.517099 4242.867382 6941.599577 6929.099402 0.923932209 0.928513545 0.939118567 1.032525768 0.895871878 0.956915053 0.927612194 0.612325951 1.001804012 1 12.75845214 -4.256542783 3.770208896 0.95840439 0.57481148 0.873931979 0.039352327 0.068709899 1.844827765 0.005658243 0.07347272 5.54E-05 4.256542783 -0.383592909 AAVGVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AAVGVKK 7 1 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 1 ; AAVGVK(1)K;AAVGVK(1)K 99.919 0.0072543 9353700 8495.1 7861.8 7365.8 7096.7 7135.4 10084.3 6442.1 4644.7 8461.1 8418.3 FALSE TRUE FALSE 7822.703871 8541.33896 7638.783028 7067.335736 7050.315015 7992.702507 6622.847988 6060.847648 7532.938499 8710.835298 0.898042909 0.980541896 0.876928878 0.811326985 0.809373013 0.917558676 0.76029999 0.695782602 0.864777974 1 13.08859535 -1.266441 0.155965577 1.017712239 9.72E-18 0.525354316 0.062012053 24.29903047 0.260706047 0.102710866 5.581783531 0.05414508 1.266441 -1.017712239 AAVLS(ph)DS(ph)EDEEKASAK ddPTM_HeLa_Curcumin_4h_R1 1 AAVLSDSEDEEKASAK 16 1 Q96ST2-3;Q96ST2;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 2 0 AAVLS(1)DS(1)EDEEKASAK 115.09 0.0049621 53461000 8919.3 7493.6 8931 8639.8 9101.9 9123.9 8235.4 8231 8965.2 9159.3 TRUE FALSE FALSE 8213.327993 8141.313393 9261.990717 8604.050797 8993.365787 7231.500292 8466.46316 10740.59401 7981.73999 9477.584993 0.866605575 0.859007163 0.977252193 0.907831563 0.948909009 0.763010862 0.893314401 1.133262748 0.842170236 1 13.21030377 -9.498705077 1.265442589 0.999652361 0.908086999 0 0.102971613 0.770337017 2.221009395 0.060131354 0.014831386 3.17E-10 9.498705077 -0.091565362 AAVLS(ph)DSEDEEK ddPTM_HeLa_Curcumin_4h_R1 2 AAVLSDSEDEEK 12 0 Q96ST2-3;Q96ST2;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 0 AAVLS(0.5)DS(0.5)EDEEK;AAVLS(0.72)DS(0.28)EDEEK ; 196.7 2.22E-06 12629900 5404.8 3989.9 4030.1 4357.5 5088.8 3753.6 2974.3 2915.9 3886.8 3496.4 TRUE FALSE FALSE 4977.004377 4334.769177 4179.459051 4339.46982 5028.119384 2975.061048 3057.750853 3804.944487 3460.427764 3617.89964 1.37566126 1.198145225 1.155216968 1.199444499 1.389789625 0.822317185 0.845172934 1.051699844 0.956474228 1 11.82093667 -5.246810589 24.88492492 1.195048047 0.900274266 0.442911786 0.141125928 572.1828476 973333.9696 0.022291499 0.056559151 5.66E-06 5.246810589 -0.294773781 AAVLS(ph)DSEDEEKAS(ph)AK ddPTM_HeLa_Curcumin_4h_R1 1 AAVLSDSEDEEKASAK 16 1 Q96ST2-3;Q96ST2;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 2 0 AAVLS(0.999)DS(0.005)EDEEKAS(0.996)AK 144.15 0.0015059 29919000 5678.7 5211.4 5921.4 5523.7 5237.4 5893.7 5468.2 5002.5 5727.8 4838.9 TRUE FALSE FALSE 5229.224903 5661.850194 6140.852293 5500.844393 5174.947426 4671.280184 5621.622975 6527.739221 5099.47467 5007.051415 1.04437212 1.130775326 1.22644083 1.098619514 1.033531913 0.932940327 1.122741212 1.303709245 1.018458619 1 12.28974555 -1.000000019 0.028417098 0.504500161 1.915347276 0.178492746 0.095164435 1727.862239 3.807300871 62.13054666 142.5334943 0.099999996 1.000000019 1.410847115 AAVLSDS(ph)EDEEKASAK ddPTM_HeLa_Curcumin_4h_R1 2 AAVLSDSEDEEKASAK 16 1 Q96ST2-3;Q96ST2;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 0 AAVLSDS(1)EDEEKASAK;AAVLS(0.014)DS(0.986)EDEEKASAK ; 130.95 0.0017082 32070000 4973.4 3951.62 4163.7 4722.7 4491.6 5785.9 6326.1 5508.9 4336.9 4252 TRUE FALSE FALSE 4579.750142 4293.180425 4318.010385 4703.158719 4438.040604 4585.839119 6503.59334 7188.53825 3861.15292 4399.756684 1.040909867 0.975776783 0.981420268 1.068958821 1.008701372 1.042293802 1.478171137 1.633849044 0.877583284 1 12.10320803 -4.69786598 3.256780997 1.015977244 1.608065604 0.948429789 0.052375392 0.021150147 0.436880479 0.004317309 0.01935892 2.01E-05 4.69786598 0.59208836 AAVPQK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AAVPQKK 7 1 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4;A8MXE8;Q7Z5J4-4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 0 1 ; AAVPQK(1)K;AAVPQK(1)K 81.635 0.016506 5817800 10899.4 11146.6 12295 9235.4 8660.3 13096.8 8046.6 4594.9 11129.3 9826 FALSE TRUE FALSE 10036.70099 12110.06244 12750.66352 9197.186362 8557.031579 10380.37605 8272.36594 5995.863858 9908.443634 10167.45277 0.987140164 1.191061588 1.254066658 0.904571339 0.841610163 1.020941654 0.813612429 0.589711503 0.974525661 1 13.31167067 -3.833937904 0.868139931 1.019680507 2.27E-19 0.595198222 0.114117064 2.42487027 0.815195471 0.018848119 2.805003654 0.000146576 3.833937904 -1.019680507 AAVPSGAS(ph)TGIYEALELR ddPTM_HeLa_Curcumin_4h_R1 1 AAVPSGASTGIYEALELR 18 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798;P13929-3;P09104-2;F5H1C3;P13929-2;E5RI09;E5RG95;K7EKN2;P09104;K7EPM1;E5RGZ4;F5H0C8;P13929 P06733 ENO1;ENO3;ENO2 Alpha-enolase;Enolase;Beta-enolase;Gamma-enolase 1 0 AAVPS(0.161)GAS(0.785)T(0.054)GIYEALELR 139.12 0.00031255 4162100 750.14 817.3 688.71 652.69 916.43 975.64 766.71 783.58 776.4 989.11 TRUE FALSE FALSE 690.7656275 887.9437702 714.2341985 649.9893417 905.5021708 773.2812663 788.2218191 1022.489935 691.2308625 1023.481499 0.674917552 0.867571882 0.697847689 0.635076787 0.884727444 0.755540053 0.770137829 0.999031185 0.675372113 1 9.999269308 -9.483887012 1.201929948 1.001099057 0.770860517 0 0.143567997 0.380873115 0.976913384 0.072917073 0.017473544 3.28E-10 9.483887012 -0.23023854 AAVPSGAST(ph)GIYEALELR ddPTM_HeLa_Curcumin_4h_R1 1 AAVPSGASTGIYEALELR 18 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798;P13929-3;P09104-2;F5H1C3;P13929-2;E5RI09;E5RG95;K7EKN2;P09104;K7EPM1;E5RGZ4;F5H0C8;P13929 P06733 ENO1;ENO3;ENO2 Alpha-enolase;Enolase;Beta-enolase;Gamma-enolase 1 0 AAVPS(0.011)GAS(0.3)T(0.689)GIYEALELR 164.82 5.28E-05 4053100 684.18 531.72 595.58 665.76 753.12 981.24 909.12 791.12 757.99 551.68 TRUE FALSE FALSE 630.0264311 577.6795075 617.6527187 663.0052615 744.1395359 777.7197631 934.6274604 1032.328846 674.8403934 570.8508389 1.103662092 1.011962264 1.08198618 1.161433454 1.303562131 1.362387002 1.637253371 1.808403835 1.182165896 1 9.156970014 -4.38443574 0.584518007 1.038413624 2.286621045 0.946810251 0.059078648 0.339256253 0.085453392 0.008486782 0.276894563 4.13E-05 4.38443574 1.248207421 AAVPSGASTGIY(ph)EALELR ddPTM_HeLa_Curcumin_4h_R1 1 AAVPSGASTGIYEALELR 18 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798;P13929-3;P09104-2;F5H1C3;P13929-2;E5RI09;E5RG95;K7EKN2;P09104;K7EPM1;E5RGZ4;F5H0C8;P13929 P06733 ENO1;ENO3;ENO2 Alpha-enolase;Enolase;Beta-enolase;Gamma-enolase 1 0 AAVPSGAST(0.001)GIY(0.999)EALELR 171.11 5.45E-05 4360200 1648.3 1233.3 1402.5 1278.9 1733 2105.5 1568.2 1303.5 1668.9 1163.7 TRUE FALSE FALSE 1517.835316 1339.900957 1454.477884 1273.608251 1712.335107 1668.795566 1612.199471 1700.931149 1485.825845 1204.138488 1.260515572 1.112746557 1.207899173 1.057692502 1.42204167 1.38588342 1.338882103 1.412571034 1.233932691 1 10.23378561 -1.000000001 0.032224769 2.20E-12 3.119838025 0.380655681 0.111960446 533.8192644 1.330876898 40.03281974 102.5328368 0.1 1.000000001 3.119838024 AAVPSGASTGIYEALELR ddPTM_HeLa_Curcumin_4h_R1 3 AAVPSGASTGIYEALELR 18 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798;P13929-3;P09104-2;F5H1C3;P13929-2;E5RI09;E5RG95;K7EKN2;P09104;K7EPM1;E5RGZ4;F5H0C8;P13929 P06733 ENO1;ENO3;ENO2 Alpha-enolase;Enolase;Beta-enolase;Gamma-enolase 0 0 ;; ;; 194.86 3.60E-08 37065890 1893.35 1318.41 1704.97 1828.29 1787.09 2086 1697.17 2081.29 1887.3 1719.01 FALSE FALSE TRUE 1743.48935 1432.367486 1768.157688 1820.72502 1765.780119 1653.340086 1744.788023 2715.86574 1680.267912 1778.74547 0.980179222 0.805268382 0.994047613 1.023600651 0.992710958 0.929497848 0.980909328 1.526843377 0.94463651 1 10.79664437 -4.261546886 8.012891956 0.975957672 1.531260219 0.888899421 0.059789898 0.021637055 17.04681913 0.008183626 0.064776047 5.48E-05 4.261546886 0.555302547 AAVQELSS(ph)SILAGEDPEER ddPTM_HeLa_Curcumin_4h_R1 1 AAVQELSSSILAGEDPEER 19 0 E7ES96;P49768-7;P49768-2;P49768 E7ES96 PSEN1 Presenilin;Presenilin-1;Presenilin-1 NTF subunit;Presenilin-1 CTF subunit;Presenilin-1 CTF12 1 0 AAVQELS(0.002)S(0.912)S(0.086)ILAGEDPEER 279.27 9.54E-69 3588000 878.2 566.1 597.29 740.84 845.89 1308.1 791.1 306.08 933.7 775.79 TRUE FALSE FALSE 808.6895433 615.0311615 619.4260928 737.7746004 835.8033142 1036.785315 813.2961369 399.402383 831.275446 802.7486448 1.007400696 0.766156587 0.77163144 0.919060537 1.041176861 1.291544148 1.013139221 0.497543516 1.035536405 1 9.648804514 AAVSWLTPAPSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AAVSWLTPAPSKK 13 1 Q9H9L3 Q9H9L3 ISG20L2 Interferon-stimulated 20 kDa exonuclease-like 2 0 1 ; AAVSWLTPAPSK(1)K;AAVSWLTPAPSK(1)K 193.85 7.89E-14 1771610 1649.68 1286.04 1470.25 1709.73 1262.8 1951.81 994.54 1507.79 1625.15 1301.14 FALSE TRUE FALSE 1519.106087 1397.199567 1524.738758 1702.65559 1247.741935 1546.982605 1022.444116 1967.50823 1446.875111 1346.354518 1.12831061 1.037764978 1.132494256 1.264641346 0.926755857 1.149015793 0.759416708 1.461359696 1.074661311 1 10.39484263 -9.415993109 1.052578881 0.997954942 1.097848659 0.015262104 0.178080924 1.575322853 3.017115581 0.120662556 0.028059327 3.84E-10 9.415993109 0.099893717 AAVTPGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AAVTPGKK 8 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 ; AAVTPGK(1)K;AAVTPGK(1)K 91.853 0.0070326 427280000 22934 18386 21344 18085.4 18688.7 23503 22083 19277.4 21308 16545.7 FALSE TRUE FALSE 21118.7497 19975.20391 22135.02742 18010.56741 18465.84946 18628.21287 22702.58955 25154.99052 18970.56571 17120.66184 1.233524141 1.166730825 1.292883863 1.051978456 1.078571005 1.088054483 1.326034575 1.469276757 1.108050955 1 14.06345085 -13.52287875 0.036207483 1.70E-12 1.854204096 0.30443977 0.116006124 800.9472025 2.320609741 98.21242794 35.44981943 3.00E-14 13.52287875 1.854204096 AAVVTS(ph)PPPTTAPHK ddPTM_HeLa_Curcumin_4h_R1 4 AAVVTSPPPTTAPHK 15 0 E7EV99;E7ENY0;P35611-5;P35611-2;P35611-6;P35611-4;P35611;P35611-3;A0A0A0MSR2;D6RJE2;D6RAH3;D6RF25 E7EV99 ADD1 Alpha-adducin 1 0 AAVVT(0.054)S(0.946)PPPTTAPHK;AAVVT(0.026)S(0.974)PPPTTAPHK;AAVVT(0.129)S(0.871)PPPTTAPHK;AAVVT(0.169)S(0.831)PPPTTAPHK ;;; 124.5 0.0004653 342246000 21806.4 18463.5 20187.2 19115.7 18698 19324.1 16736.6 15361.8 19143.5 19611.4 TRUE FALSE FALSE 20080.40043 20059.40267 20935.35539 19036.6043 18475.03856 15316.06383 17206.18395 20045.5421 17043.50594 20292.89469 0.989528637 0.988493903 1.031659392 0.938092105 0.910419082 0.754750077 0.847892044 0.987810877 0.839875543 1 14.30868705 -5.827752911 2.498006005 0.996436055 0.860535369 0.228548373 0.074297168 0.153790303 1.955173935 0.008029009 0.016361354 1.49E-06 5.827752911 -0.135900686 AAYEAELGDAR ddPTM_HeLa_Curcumin_4h_R1 3 AAYEAELGDAR 11 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ;; ;; 169.09 1.67E-07 72505100 10163.1 8062.1 8679.2 9444.5 9305.2 11762 9547.7 8459.4 10049.8 8165.8 FALSE FALSE TRUE 9358.679911 8758.952 9000.858787 9405.421161 9194.241567 9322.428615 9815.582766 11038.63212 8947.362083 8449.560942 1.107593634 1.036616229 1.065245739 1.113125431 1.088132464 1.103303317 1.161667788 1.306414877 1.058914439 1 13.04466066 -1 0.502247855 1.050106616 8.986286833 0.863194073 0.029482574 33.33512233 0.318229298 0.008142097 281.150926 0.1 1 7.936180218 AAYGDLS(ph)S(ph)EEEEENEPESLGVVYK ddPTM_HeLa_Curcumin_4h_R1 2 AAYGDLSSEEEEENEPESLGVVYK 24 0 O15541 O15541 RNF113A RING finger protein 113A 2 0 AAY(0.002)GDLS(0.999)S(0.999)EEEEENEPESLGVVYK;AAY(0.003)GDLS(0.994)S(0.997)EEEEENEPES(0.006)LGVVYK ; 81.534 0.0004841 17790000 7691.7 5619.5 6052.7 6711.3 5989 7683.9 6207.7 5090.9 6716.2 5719.2 TRUE FALSE FALSE 7082.893829 6105.22454 6277.018386 6683.530419 5917.585087 6090.172525 6381.871355 6643.091974 5979.449663 5917.941774 1.196850881 1.031646605 1.060675929 1.129367384 0.999939728 1.029103151 1.078393739 1.12253419 1.01039346 1 12.53087979 -5.781880733 24.98142873 1.089598077 1.056957751 0 0.063535445 746.1970926 911926.9181 0.011943925 0.021668081 1.65E-06 5.781880733 -0.032640325 AAYLQETGKPLDETLK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 AAYLQETGKPLDETLKK 17 2 P04083;Q5T3N1;Q5T3N0 P04083 ANXA1 Annexin A1;Annexin 0 1 AAYLQETGKPLDETLK(1)K 102.39 0.0011399 4352700 408.19 743.56 411.47 577.12 946.21 1398.2 917.02 1062.3 1292.7 502.09 FALSE TRUE FALSE 375.8813308 807.8300132 426.7194402 574.7320304 934.9270637 1108.197559 942.7491132 1386.19038 1150.894044 519.5375901 0.723492078 1.554901952 0.821344689 1.106237626 1.799536899 2.133045963 1.81459269 2.668123358 2.215227668 1 9.021084326 -5.421884714 0.786111426 0.890425818 2.477152139 0.337415249 0.506191655 0.276066989 0.273143896 0.049531026 0.272741091 3.79E-06 5.421884714 1.586726321 ACANPAAGSVILLENLR ddPTM_HeLa_Curcumin_4h_R1 1 ACANPAAGSVILLENLR 17 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 0 169.17 0.0001709 941870 0 138.96 148.16 139.1 185.92 330.45 229.5 229.4 319.6 0 FALSE FALSE TRUE 0 150.9710832 153.6509399 138.5244411 183.7030254 261.9109451 235.9391523 299.343004 284.5406796 0 0 ACAS(ph)PSAQVEGS(ph)PVAGSDGSQPAVK ddPTM_HeLa_Curcumin_4h_R1 1 ACASPSAQVEGSPVAGSDGSQPAVK 25 0 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 2 0 ACAS(0.835)PS(0.176)AQVEGS(0.988)PVAGS(0.002)DGSQPAVK 64.7 0.0042019 18172000 4583.6 4244.8 4100.6 4287.3 4165.2 4985.7 3862.2 2279.1 4380.7 4601.2 TRUE FALSE FALSE 4220.803223 4611.701598 4252.571843 4269.560289 4115.53271 3951.60962 3970.562937 2973.987098 3900.14817 4761.091358 0.886520108 0.968622791 0.893192658 0.896760841 0.864409523 0.829979793 0.83396067 0.624643989 0.819171042 1 12.2170766 -2.871540652 0.36877127 0.956195089 4.09E-33 0.633759549 0.058418868 5.091841615 0.218479644 0.013168496 2.695511663 0.001344186 2.871540652 -0.956195089 ACAS(ph)PSAQVEGSPVAGSDGSQPAVK ddPTM_HeLa_Curcumin_4h_R1 1 ACASPSAQVEGSPVAGSDGSQPAVK 25 0 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 0 ACAS(0.793)PS(0.207)AQVEGSPVAGSDGSQPAVK 146.28 3.45E-08 30959000 5292.4 4962.5 4768.2 4944.5 4718.8 5765.9 4103.7 3938.1 5157.3 4239.7 TRUE FALSE FALSE 4873.500955 5391.436388 4944.913687 4924.040969 4662.531392 4569.987345 4218.838777 5138.808561 4591.557093 4387.029259 1.110888637 1.228949266 1.12716679 1.122408965 1.062799247 1.041704323 0.961661874 1.171364096 1.046621032 1 12.09902861 -3.880250559 16.72360491 1.070098598 11.36008758 0.124916453 0.071395772 167.8597742 23462.82497 0.011026769 56.96888775 0.00013175 3.880250559 10.28998899 ACASPS(ph)AQVEGS(ph)PVAGSDGSQPAVK ddPTM_HeLa_Curcumin_4h_R1 1 ACASPSAQVEGSPVAGSDGSQPAVK 25 0 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 2 0 ACAS(0.329)PS(0.672)AQVEGS(0.998)PVAGSDGSQPAVK 86.81 0.00014846 21253000 5329.1 4065.1 4343.8 4449.4 4491.5 5505.5 4297.1 2649 4673.9 4664.3 TRUE FALSE FALSE 4907.296112 4416.46913 4504.785049 4430.989562 4437.941796 4363.59724 4417.665061 3456.667906 4161.184864 4826.384078 1.016764524 0.915067897 0.933366466 0.91807645 0.919516915 0.904113135 0.915315688 0.716202409 0.862174414 1 12.23672701 -2.156066746 0.295270591 1.011354968 4.32E-12 0.368777582 0.061609908 9.119291734 0.215299138 0.016885272 4.295879228 0.006981251 2.156066746 -1.011354968 ACESVS(ph)TRAAHMCSAGLAGVINRMRESR ddPTM_HeLa_Curcumin_4h_R1 1 ACESVSTRAAHMCSAGLAGVINRMRESR 28 3 H7BXV0;C9JQD1;A0A5F9ZGW4;A0A5F9ZHE0;P35557-3;P35557;P35557-2 H7BXV0 GCK Hexokinase;Glucokinase 1 0 ACES(0.148)VS(0.814)T(0.035)RAAHMCS(0.002)AGLAGVINRMRESR 42.806 0.0092288 0 63.138 0 271.53 75.277 66.072 0 127.53 0 0 166.72 TRUE FALSE FALSE 58.14056068 0 281.5931407 74.96552372 65.28413455 0 131.1081486 0 0 172.5135076 0.337020338 0 1.632296187 0.434548719 0.378429118 0 0.759987727 0 0 1 7.430565517 -13.52287874 0.276396576 5.193668427 0.398274009 0 0.560437478 62.10728603 0.836625863 143.5453478 0.219092425 3.00E-14 13.52287874 -4.795394418 ACGNFGIPCELR ddPTM_HeLa_Curcumin_4h_R1 2 ACGNFGIPCELR 12 0 E9PBS1;P22234;P22234-2;D6RF62 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 0 0 ; ; 115.57 0.0015247 4790600 1812.37 1401.74 1765.77 1623.18 1905.74 2214.4 1666.7 1370.17 2031.58 1348.15 FALSE FALSE TRUE 1668.919002 1522.90016 1831.21099 1616.463711 1883.015295 1755.108479 1713.463116 1787.928526 1808.720757 1394.998112 1.196359327 1.09168618 1.312697826 1.158756917 1.34983358 1.258143981 1.228290635 1.281670928 1.296575774 1 10.44604745 -9.813286608 0.219039567 0.791175789 1.301970436 0 0.112301368 3.639957886 0.201537282 0.517790693 0.070187667 1.54E-10 9.813286608 0.510794647 ACGVSRPVIACSVTIK ddPTM_HeLa_Curcumin_4h_R1 1 ACGVSRPVIACSVTIK 16 1 A0A3B3IRU2;B1AHD1;A0A3B3IUA2;P55769 A0A3B3IRU2 NHP2L1 "NHP2-like protein 1;NHP2-like protein 1, N-terminally processed" 0 0 97.223 0.0049752 3424200 2190.6 1565.6 1824.3 2262 1724.6 1353.1 1039.8 951.69 2143.6 1618.5 FALSE FALSE TRUE 2017.211698 1700.923488 1891.910163 2252.640443 1704.035271 1072.451807 1068.97399 1241.8559 1908.452443 1674.742755 1.204490477 1.015632689 1.129672099 1.345066541 1.017490756 0.640368083 0.638291455 0.74152039 1.139549604 1 10.70972379 -5.337500668 4.416951831 1.11233053 0.669134002 0.817887291 0.09760006 0.077852879 2.850075611 0.016118402 0.037744786 4.60E-06 5.337500668 -0.443196528 ACKVDS(ph)PTVTTTLK ddPTM_HeLa_Curcumin_4h_R1 1 ACKVDSPTVTTTLK 14 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866 Q07866-6 KLC1 Kinesin light chain 1 1 0 ACKVDS(0.943)PT(0.038)VT(0.017)T(0.002)TLK 179.79 0.0012908 42207000 2393.7 2152.9 1742.7 2077.7 2039.2 3037.9 1926.4 916.02 2779.7 2097.7 TRUE FALSE FALSE 2204.236119 2338.987083 1807.285995 2069.103028 2014.883872 2407.805296 1980.449599 1195.310281 2474.773864 2170.594919 1.015498608 1.077578807 0.83262242 0.953242362 0.928263424 1.109283577 0.912399445 0.550683258 1.14013621 1 11.0838748 -4.289406639 3.498136823 0.996370034 0.50937485 0.71331459 0.086282161 0.088981589 1.894232422 0.00975682 0.10918555 5.14E-05 4.289406639 -0.486995185 ACPGPPPPS(ph)PEPLAR ddPTM_HeLa_Curcumin_4h_R1 2 ACPGPPPPSPEPLAR 15 0 A0A087WSV0;Q9HB09-3;Q9HB09 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 0 ACPGPPPPS(1)PEPLAR;ACPGPPPPS(1)PEPLAR ; 160.46 0.00030732 38553000 4221.9 3411.8 3764.2 5104 3751.7 5120.3 3115.7 2545.6 5892.6 4332.1 TRUE FALSE FALSE 3887.73216 3706.700789 3903.704563 5082.881 3706.963428 4058.292062 3203.118157 3321.741721 5246.196523 4482.640153 0.867286248 0.82690126 0.870849417 1.13390342 0.82695985 0.905335232 0.714560627 0.741023506 1.170336307 1 12.13013298 -4.842538164 2.321495111 0.930894615 0.71838463 0.356985911 0.116135555 0.226014197 2.362041412 0.013295489 0.060203486 1.44E-05 4.842538164 -0.212509985 ACPRPEGLNFQDLK ddPTM_HeLa_Curcumin_4h_R1 2 ACPRPEGLNFQDLK 14 1 Q5TEJ0;P15927;P15927-2;P15927-3 Q5TEJ0 RPA2 Replication protein A 32 kDa subunit 0 0 ; ; 101.39 0.0026727 2826100 685.46 811.68 905.68 704.89 960.86 1021.4 792.41 773.19 841.82 716.22 FALSE FALSE TRUE 631.2051177 881.8380024 939.2452975 701.973352 949.4023721 809.5501264 814.6428919 1008.932072 749.4744521 741.1085917 0.851703954 1.189890405 1.267351786 0.94719365 1.281057031 1.092350211 1.099222032 1.361382236 1.011288306 1 9.53354114 -7.25283699 24.83072981 0.929971311 1.169327576 0.426047989 0.117143538 357.0566778 1030641.964 0.018949542 0.023013509 5.59E-08 7.25283699 0.239356265 ACQSIYPLHDVFVR ddPTM_HeLa_Curcumin_4h_R1 3 ACQSIYPLHDVFVR 14 0 P61247;H0Y9Y4;D6RAT0;D6R9B6;D6RG13;D6RB09 P61247 RPS3A 40S ribosomal protein S3a 0 0 ;; ;; 97.223 0.0028171 25792400 7428.8 6340.22 6086.58 6200.3 7236.64 13876 8298.3 6517 8359.6 6742.4 FALSE FALSE TRUE 6840.802641 6888.240365 6312.154009 6174.644801 7150.347794 10997.96119 8531.127964 8504.003299 7442.572795 6976.697898 0.980521551 0.987321003 0.904748077 0.885038293 1.024889984 1.576384895 1.222803121 1.218915227 1.066775845 1 12.76832865 -5.418768411 7.769233002 0.975687326 1.32661097 0.719804993 0.103519009 0.105237802 7.029230108 0.013515767 0.0303015 3.81E-06 5.418768411 0.350923644 ACTGLSGPGSGSKS(ph)PPATR ddPTM_HeLa_Curcumin_4h_R1 2 ACTGLSGPGSGSKSPPATR 19 1 I3L2J0;I3L2I4 I3L2J0 CIC 1 0 ACTGLSGPGS(0.001)GS(0.073)KS(0.925)PPAT(0.001)R;ACTGLSGPGS(0.001)GS(0.034)KS(0.962)PPAT(0.003)R ; 119.18 0.00010804 109969000 8783.9 6385.4 6932.1 7570.5 7385.5 8697.9 6881.7 4010.7 9943.2 8262.7 TRUE FALSE FALSE 8088.645046 6937.325523 7189.009724 7539.175277 7297.432736 6893.857494 7074.781981 5233.543967 8852.455837 8549.82821 0.946059365 0.811399405 0.840836745 0.881792604 0.853518054 0.806315323 0.827476507 0.612122705 1.035395755 1 13.06167972 -1.912081525 0.16217176 1.038294175 1.88E-17 0.768809018 0.054052914 16.28461672 0.216924551 0.09754856 3.850909718 0.012243863 1.912081525 -1.038294175 ACWSLGNAYTALGNHDQAMHFAEK ddPTM_HeLa_Curcumin_4h_R1 1 ACWSLGNAYTALGNHDQAMHFAEK 24 0 A0A2R8Y6E3;P81274;A0A2R8YCX1 A0A2R8Y6E3 GPSM2 G-protein-signaling modulator 2 0 0 41.256 0.01938 7714100 1665.1 1641.6 1476 1567.7 1766.6 2186.8 1499.5 667.06 1635.5 1665.7 FALSE FALSE TRUE 1533.305578 1783.492589 1530.701858 1561.213273 1745.534449 1733.23303 1541.571934 870.4435232 1456.089742 1723.582951 0.889603588 1.034758779 0.888092945 0.905795263 1.012735968 1.005598848 0.894399619 0.505019803 0.844803983 1 10.75119502 -4.268806926 3.62298332 0.953518895 0.457882243 0.822118682 0.061315574 0.072953137 1.736477085 0.007858034 0.096487924 5.39E-05 4.268806926 -0.495636653 ADAASSLTVDVT(ph)PPTAK ddPTM_HeLa_Curcumin_4h_R1 3 ADAASSLTVDVTPPTAK 17 0 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 0 ADAASSLT(0.023)VDVT(0.954)PPT(0.023)AK;ADAASSLTVDVT(0.998)PPT(0.001)AK;ADAASSLTVDVT(0.985)PPT(0.015)AK ;; 220.59 2.56E-15 136286000 9180.9 7682.4 7578.9 8481.6 7738.4 10346.9 8085.8 6932.7 8573.9 8170.9 TRUE FALSE FALSE 8454.222077 8346.432424 7859.780701 8446.505387 7646.124634 8200.836306 8312.665786 9046.448316 7633.364621 8454.838167 0.999927132 0.987178259 0.929619296 0.999014436 0.904349023 0.969957809 0.983184494 1.069972971 0.902839826 1 13.04556143 -6.997210982 24.92512844 0.999628071 0.972566561 0 0.051159884 161.9587769 1447385.92 0.006399811 0.00838543 1.01E-07 6.997210982 -0.02706151 ADADPSPTS(ph)PPTAR ddPTM_HeLa_Curcumin_4h_R1 2 ADADPSPTSPPTAR 14 0 Q9NWZ5;Q9NWZ5-3;Q9NWZ5-2 Q9NWZ5 UCKL1 Uridine-cytidine kinase-like 1 1 0 ADADPS(0.003)PT(0.046)S(0.934)PPT(0.017)AR;ADADPS(0.004)PT(0.051)S(0.719)PPT(0.226)AR ; 101.72 0.0053782 90455000 7721.4 6577.8 6405.1 6137.1 7191.7 8193.7 5463 5004.9 8102.1 6914.4 TRUE FALSE FALSE 7110.243042 7146.355722 6642.47864 6111.706306 7105.943675 6494.234258 5616.277077 6530.87097 7213.3199 7154.674885 0.993789817 0.998837241 0.928410969 0.85422558 0.993188899 0.907691036 0.784980054 0.912811704 1.008196741 1 12.8046705 -5.934592635 0.530505094 1.002473501 0.847319457 0.501922651 0.050256301 0.67453915 0.323739146 0.012217126 0.048466715 1.16E-06 5.934592635 -0.155154044 ADAEGESDLENSR ddPTM_HeLa_Curcumin_4h_R1 1 ADAEGESDLENSR 13 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 145.14 0.00038892 1379400 705.04 559.73 470.06 551.17 649.16 780.11 591.93 378.03 531.46 468.92 FALSE FALSE TRUE 649.23534 608.1105671 487.4808371 548.8894046 641.419191 618.3063923 608.5379627 493.2896068 473.1601676 485.2149351 1.338036596 1.25328081 1.004669893 1.13122941 1.321927963 1.274293818 1.254161648 1.016641433 0.975155819 1 8.922480148 -9.563519135 1.351779301 1.000515316 1.218489264 0.348795924 0.112319709 0.419694408 1.379650838 0.08260771 0.019631092 2.73E-10 9.563519135 0.217973947 ADAGKEGNNPAENGDAK ddPTM_HeLa_Curcumin_4h_R1 2 ADAGKEGNNPAENGDAK 17 1 P05204 P05204 HMGN2 Non-histone chromosomal protein HMG-17 0 0 ; ; 168.55 8.81E-05 5885400 4932.7 3470 3769.9 4189.8 3614.3 5693.3 4105.5 3264.8 5947.6 5255.3 FALSE FALSE TRUE 4542.27159 3769.931338 3909.61581 4172.463718 3571.201833 4512.445403 4220.689281 4260.222491 5295.16316 5437.921284 0.835295576 0.693266993 0.718954101 0.767290202 0.65672187 0.829810725 0.776158583 0.783428496 0.973747666 1 12.40883955 -8.25326337 0.780519467 0.982119679 0.747652729 0.76156109 0.051816289 0.197460164 0.258365512 0.021002607 0.012688068 5.58E-09 8.25326337 -0.23446695 T(ph)SPTPGDFPK ddPTM_HeLa_Curcumin_4h_R1 1 TSPTPGDFPK 10 0 Q9UPU7;C9JW56;Q9UPU7-2 Q9UPU7 TBC1D2B TBC1 domain family member 2B 1 0 T(0.868)S(0.132)PTPGDFPK 133.42 0.007062 10636000 4781.7 4482.9 4111.8 3478.9 3165.6 2565 1523.3 1638.1 4563.2 4611.3 TRUE FALSE FALSE 4403.223399 4870.381901 4264.186925 3464.505234 3127.852288 2032.990086 1566.039698 2137.549149 4062.628377 4771.542332 0.92280925 1.020714386 0.893670564 0.7260766 0.655522276 0.426065608 0.328204088 0.447978662 0.851428761 1 12.22023996 -5.71191246 1.077527757 0.96886969 0.36457237 0.933656902 0.061761439 0.069755427 0.156196723 0.008512108 0.02645797 1.94E-06 5.71191246 -0.60429732 down ADAPDAGAQS(ph)DSELPSYHQNDVSLDR ddPTM_HeLa_Curcumin_4h_R1 4 ADAPDAGAQSDSELPSYHQNDVSLDR 26 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 0 ADAPDAGAQS(0.983)DS(0.017)ELPSYHQNDVSLDR;ADAPDAGAQS(0.995)DS(0.005)ELPSYHQNDVSLDR;ADAPDAGAQS(0.594)DS(0.357)ELPS(0.047)Y(0.002)HQNDVSLDR;ADAPDAGAQS(0.991)DS(0.009)ELPSYHQNDVSLDR ;;; 186.45 1.67E-15 335753000 8586.2 8328.4 6357.9 6077.1 12783.9 19684.3 7447.8 4703.12 11309 8280.6 TRUE FALSE FALSE 7906.59321 9048.269785 6593.529367 6051.95457 12631.46034 15601.55429 7656.765223 6137.079637 10068.43099 8568.350234 0.922767277 1.05601073 0.769521458 0.706315032 1.474199816 1.820835268 0.893610207 0.716249858 1.175072297 1 13.06480174 -5.761148724 25 0.938143441 1.244937898 0.173166067 0.307153013 10.22955071 879722.7881 0.044765817 0.085258088 1.73E-06 5.761148724 0.306794457 ADDADEFGYS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 ADDADEFGYSR 11 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 0 ADDADEFGYS(1)R;ADDADEFGYS(1)R ; 120.59 0.0030443 26835000 4962.4 3850.9 3803.1 3855.3 3952.1 5201.1 4255 5776.2 4321.2 4080.1 TRUE FALSE FALSE 4569.620804 4183.754637 3944.046232 3839.34779 3904.973789 4122.333232 4374.383848 7537.33679 3847.175171 4221.883171 1.082365527 0.990968832 0.93419123 0.909392239 0.924936487 0.976420489 1.036121482 1.785302076 0.911246241 1 12.04367094 -4.261581848 5.545459484 1.007939757 1.812835437 0.938373444 0.061869005 0.028315473 3.409125605 0.009632733 0.086025521 5.48E-05 4.261581848 0.804895679 ADDADEFGYSR ddPTM_HeLa_Curcumin_4h_R1 4 ADDADEFGYSR 11 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 0 ;;; ;;; 231.38 8.99E-16 189827700 8332.1 7974.8 7606.5 8131.1 8808.8 9151.3 7349.9 6729.8 9127 7886 FALSE FALSE TRUE 7672.605493 8664.106177 7888.403581 8097.455663 8703.760813 7253.217224 7556.118413 8781.68504 8125.790935 8160.037913 0.940265912 1.061772785 0.966711634 0.992330642 1.066632399 0.88887053 0.925990601 1.076181892 0.995803086 1 12.99436014 -4.240610335 23.53730301 0.976800504 1.076182111 0.215232284 0.05308526 2542.307539 2872768.332 0.007235594 0.375495189 5.75E-05 4.240610335 0.099381607 ADDGRPFPQVIK ddPTM_HeLa_Curcumin_4h_R1 4 ADDGRPFPQVIK 12 1 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7;H3BR04;H3BMQ8;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 ;;; ;;; 140.78 5.75E-05 217362000 18787.8 16282.4 16669.4 17032.5 17193.6 21671 17328.4 17061.8 19967 17246.5 FALSE FALSE TRUE 17300.72581 17689.7781 17287.18263 16962.02403 16988.57755 17176.19032 17814.58827 22263.86428 17776.67005 17845.81459 0.969455651 0.99125641 0.968696752 0.950476311 0.951964253 0.962477237 0.998250216 1.247567835 0.996125448 1 14.12329814 -4.262064684 4.377108193 0.978356322 1.266730171 0.958825027 0.016896185 0.033010254 1.518348758 0.002778941 0.029406119 5.47E-05 4.262064684 0.288373849 ADDLGKGGNEESTK ddPTM_HeLa_Curcumin_4h_R1 2 ADDLGKGGNEESTK 14 1 H7BYH4;P00441 H7BYH4;P00441 SOD1 Superoxide dismutase [Cu-Zn] 0 0 ; ; 127.3 0.00088462 21634000 13379.9 9301.4 11205.3 10730.7 9619.6 13270.1 10579.1 10817.9 14324.3 11921.6 FALSE FALSE TRUE 12320.8668 10105.37157 11620.57828 10686.29921 9504.892553 10517.73168 10875.92107 14116.22791 12752.96013 12335.87471 0.998783393 0.819185652 0.94201494 0.866278189 0.770508195 0.852613367 0.881649768 1.144323223 1.033810769 1 13.5905724 -7.292120758 22.17372944 0.999425538 0.890107109 0.229025327 0.094806236 182.0129764 131541.8452 0.015605258 0.017847527 5.10E-08 7.292120758 -0.109318429 ADDTDSQSWRS(ph)PLK ddPTM_HeLa_Curcumin_4h_R1 1 ADDTDSQSWRSPLK 14 1 O75369-8 O75369-8 FLNB Filamin-B 1 0 ADDTDSQSWRS(0.999)PLK 75.088 0.011139 121440000 5617.8 4426.3 4725.1 5102.2 5304.3 7953.3 6898.8 4719.6 6948.1 4766.5 TRUE FALSE FALSE 5173.145202 4808.889649 4900.216363 5081.088448 5241.049687 6303.695928 7092.361761 6158.584314 6185.910813 4932.13552 1.048865178 0.975011662 0.993528329 1.030200494 1.062632944 1.278086521 1.437990041 1.248664861 1.254205362 1 12.26799673 -5.240506143 2.946215834 1.018273496 1.34734201 0.655416718 0.088410668 0.052487437 0.913100073 0.006424059 0.017677094 5.75E-06 5.240506143 0.329068515 ADEEEMLDNLPEAGDSR ddPTM_HeLa_Curcumin_4h_R1 3 ADEEEMLDNLPEAGDSR 17 0 Q9NPD8 Q9NPD8 UBE2T Ubiquitin-conjugating enzyme E2 T 0 0 ;; ;; 319.64 1.62E-111 13556600 4506.33 2929.86 3689.76 3531.29 4555.42 4538.1 3877.52 2784.2 3960.57 3449.13 FALSE FALSE TRUE 4149.649225 3183.104043 3826.505751 3516.678458 4501.099592 3596.846905 3986.312775 3633.089763 3526.10538 3568.987011 1.162696646 0.891878853 1.072154575 0.985343585 1.261170068 1.007806107 1.116931153 1.017961049 0.987984929 1 11.80129894 ADEGIS(ph)FR ddPTM_HeLa_Curcumin_4h_R1 1 ADEGISFR 8 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 1 0 ADEGIS(1)FR 102.53 0.013571 21321000 3014 2557.5 2584.1 2549.6 2576.3 3562.7 2085 1645.1 3088.2 2411.4 TRUE FALSE FALSE 2775.43872 2778.558904 2679.869019 2539.050431 2545.579305 2823.75586 2143.499489 2146.683417 2749.432186 2495.195971 1.112312921 1.113563398 1.074011441 1.017575557 1.020192135 1.131676988 0.859050557 0.86032658 1.10189028 1 11.28493741 -4.74835555 24.99967499 1.0592506 0.859688411 0.780635597 0.044520706 94.43552663 180437.5597 0.007294789 0.026959349 1.79E-05 4.74835555 -0.199562189 ADEGISFR ddPTM_HeLa_Curcumin_4h_R1 2 ADEGISFR 8 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 0 ; ; 132.08 0.0014607 92621000 8763 6997.3 7790.3 7728.6 7599.5 10298.2 7349.8 7954.8 8875.4 7328.3 FALSE FALSE TRUE 8069.399303 7602.115433 8079.015371 7696.621101 7508.880926 8162.237235 7556.015607 10380.1819 7901.790825 7582.95788 1.064149298 1.002526396 1.065417414 1.014989299 0.990231127 1.076392269 0.996446997 1.36888297 1.042045987 1 12.88854499 -4.258096752 24.99635178 1.029037571 1.368883096 0.918485012 0.03046224 65.57803537 490373.0668 0.004373483 0.042629709 5.52E-05 4.258096752 0.339845526 ADEGKKETS(ph)PESSLIQDEIAVK ddPTM_HeLa_Curcumin_4h_R1 1 ADEGKKETSPESSLIQDEIAVK 22 2 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 ADEGKKET(0.136)S(0.796)PES(0.03)S(0.037)LIQDEIAVK 68.88 0.0019164 21109000 2392.2 2438.7 2226 2555 2118 2441.8 1970.9 1877.1 2667.6 2579.5 TRUE FALSE FALSE 2202.854846 2649.490361 2308.497518 2544.428087 2092.744233 1935.343155 2026.19815 2449.419149 2374.970954 2669.137433 0.82530589 0.992639168 0.864885221 0.953277286 0.784052633 0.725081868 0.759120952 0.917681914 0.889789684 1 11.38215788 -5.753601525 24.875465 0.919696572 0.788715319 0.43864589 0.06876366 137.1851845 435388.5545 0.011809258 0.023272133 1.76E-06 5.753601525 -0.130981254 ADEGKKETSPES(ph)SLIQDEIAVK ddPTM_HeLa_Curcumin_4h_R1 2 ADEGKKETSPESSLIQDEIAVK 22 2 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 ADEGKKET(0.421)S(0.032)PES(0.527)S(0.02)LIQDEIAVK;ADEGKKET(0.056)S(0.056)PES(0.631)S(0.257)LIQDEIAVK ; 54.828 0.011175 45000000 5746.5 4445.1 5143.3 5248.2 4672.2 5445.8 4494.1 4443.7 5547.6 4964.2 TRUE FALSE FALSE 5291.658461 4829.314637 5333.915223 5226.484339 4616.487067 4316.279693 4620.192351 5798.563674 4939.042159 5136.70558 1.030165809 0.940157959 1.038392242 1.017477887 0.898725262 0.840281699 0.899446596 1.12884875 0.961519418 1 12.32662767 -5.773318423 24.9280529 1.010617069 0.931545373 0.096145874 0.076192945 249.2290886 523005.0357 0.010629468 0.01937831 1.69E-06 5.773318423 -0.079071697 ADEHVIDQGDDGDNFYVIER ddPTM_HeLa_Curcumin_4h_R1 2 ADEHVIDQGDDGDNFYVIER 20 0 P13861-2;P13861;H7C1L0 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 0 0 ; ; 237.81 1.31E-33 85564000 8065.5 5933.2 7091.6 6329.5 7283.9 7723.2 6088.1 5992.7 8066.9 6688.3 FALSE FALSE TRUE 7427.107164 6446.03937 7354.420934 6303.310206 7197.04425 6121.321262 6258.915701 7819.846643 7181.981252 6920.717927 1.073170044 0.931411949 1.062667343 0.910788486 1.039927407 0.884492234 0.904373761 1.129918417 1.037750899 1 12.75670599 -7.265434423 24.98151528 1.03455252 0.976653386 0.102281861 0.075954321 541.7700787 3387744.798 0.012367283 0.01441077 5.43E-08 7.265434423 -0.057899134 STFVLDEFK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 STFVLDEFKR 10 1 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 1 STFVLDEFK(1)R 179.1 3.83E-16 2101000 644.42 872.13 715.73 534.16 1321.9 3462.1 1888.4 1992 1739.6 828.48 FALSE TRUE FALSE 593.413477 947.5130311 742.2555834 531.9497875 1306.137206 2744.021434 1941.383422 2599.35163 1548.770232 857.2696183 0.692213353 1.105268414 0.8658368 0.620516318 1.523601418 3.200884967 2.264612416 3.032128486 1.806631425 1 9.743605205 -5.449725764 3.892370936 0.861804719 2.765359122 0.799985104 0.400765218 0.043516919 1.258182063 0.036625616 0.084238719 3.55E-06 5.449725764 1.903554403 ADEVAPAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 ADEVAPAKK 9 1 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 0 1 ; ADEVAPAK(1)K;ADEVAPAK(1)K 118.5 0.00049452 25545000 15298.5 14068.9 15184.2 13319.4 14504.6 17367.3 13620.6 14679.8 15570 13467.8 FALSE TRUE FALSE 14087.60758 15284.95303 15746.93981 13264.28785 14331.64212 13765.12621 14002.75738 19155.60344 13862.00995 13935.80505 1.010892986 1.096811628 1.129962694 0.951813534 1.02840432 0.987752495 1.004804339 1.374560234 0.994704641 1 13.76650873 -4.260295757 24.79807521 1.016491088 1.374560363 0.813837149 0.050391209 26.60125663 576731.9053 0.006992681 0.057543093 5.49E-05 4.260295757 0.358069275 ADFCIIHYAGK ddPTM_HeLa_Curcumin_4h_R1 3 ADFCIIHYAGK 11 0 P35579;P35579-2;P35580;P35580-5;P35580-2;P35580-3;P35580-4 P35579;P35580 MYH9;MYH10 Myosin-9;Myosin-10 0 0 ;; ;; 115.23 0.00081849 33211800 20070.6 15257.6 17560.7 15269.8 16625.6 28472.9 20734.3 19292.8 20220.3 18634.1 FALSE FALSE TRUE 18481.99083 16576.39896 18211.51499 15206.61761 16427.35058 22567.29958 21316.04865 25175.08591 18002.18368 19281.63359 0.958528267 0.859698888 0.944500626 0.788658157 0.851968818 1.170403923 1.105510514 1.30565109 0.933644112 1 14.23493967 -5.210858418 8.762216561 0.945819068 1.185793075 0.71448568 0.080752837 0.215549518 35.46666618 0.012560169 0.032054999 6.15E-06 5.210858418 0.239974007 ADFREPVAVSVASPEPT(ph)DTALTLENVCDEPR ddPTM_HeLa_Curcumin_4h_R1 1 ADFREPVAVSVASPEPTDTALTLENVCDEPR 31 1 Q86TB3 Q86TB3 ALPK2 Alpha-protein kinase 2 1 0 ADFREPVAVSVAS(0.034)PEPT(0.959)DT(0.007)ALTLENVCDEPR 118.41 5.61E-13 8175900 633.18 401.78 686.45 500.07 490.95 573.49 338.54 492.4 687.32 544.79 TRUE FALSE FALSE 583.0631349 436.5080729 711.8904409 498.0008428 485.0957419 454.5417094 348.0385213 642.5304933 611.9227156 563.7214119 1.034310783 0.774332966 1.262840875 0.883416582 0.860523889 0.8063233 0.617394539 1.139801469 1.08550554 1 9.138838556 -6.019281819 24.81643742 1.014124045 0.839986705 0.208893548 0.163111403 752.1408287 968034.5324 0.021907674 0.036714204 9.57E-07 6.019281819 -0.174137341 DSGPLPT(ph)PPGVSLLGEPPKDYR ddPTM_HeLa_Curcumin_4h_R1 2 DSGPLPTPPGVSLLGEPPKDYR 22 1 A0A087WZ13;E9PAU2;Q8IY67-2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 0 DS(0.253)GPLPT(0.746)PPGVS(0.001)LLGEPPKDYR;DS(0.02)GPLPT(0.98)PPGVSLLGEPPKDYR ; 96.317 0.0001588 43552000 2927.9 2804.1 3081 2676.29 3149.1 6474 6055.7 5477.6 3365 2387.95 TRUE FALSE FALSE 2696.153625 3046.473909 3195.18457 2665.216221 3111.549039 5131.219423 6225.606644 7147.695024 2995.867919 2470.931085 1.091148856 1.232925486 1.293109545 1.07862831 1.259261765 2.076633968 2.519538761 2.892713224 1.212444951 1 11.27083906 -4.999101839 1.379405007 1.073795793 2.905133561 0.97041889 0.11037008 0.055430515 0.181261422 0.017052535 0.095934404 1.00E-05 4.999101839 1.831337768 up ADGGTGDSS(ph)PSPGSSLPSPLSDPR ddPTM_HeLa_Curcumin_4h_R1 1 ADGGTGDSSPSPGSSLPSPLSDPR 24 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 0 ADGGT(0.001)GDS(0.126)S(0.731)PS(0.126)PGS(0.011)S(0.004)LPSPLSDPR 116.09 7.23E-07 7938600 2900.1 2577.9 2471.6 2962.5 3595.3 3365 2298.6 2768.8 3360.1 2574.2 TRUE FALSE FALSE 2670.554025 2800.722189 2563.19967 2950.24196 3552.428396 2667.061069 2363.09253 3612.994374 2991.505437 2663.653258 1.002590715 1.051458999 0.962287288 1.107592345 1.33366773 1.001279375 0.887162217 1.356405667 1.123083655 1 11.37919058 -6.173174256 6.286717156 1.003275866 1.127914282 0.124681818 0.136783015 0.319912205 18.8898673 0.018842611 0.031411283 6.71E-07 6.173174256 0.124638416 ADGGTGDSSPS(ph)PGSSLPSPLSDPR ddPTM_HeLa_Curcumin_4h_R1 1 ADGGTGDSSPSPGSSLPSPLSDPR 24 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 0 ADGGTGDS(0.006)S(0.251)PS(0.59)PGS(0.126)S(0.027)LPSPLSDPR 198.49 1.07E-14 19787000 1309.7 713.45 1034.8 1406.4 984.02 1146.5 880.79 1007.6 1500 1231.7 TRUE FALSE FALSE 1206.035863 775.1174389 1073.150598 1400.580689 972.2862042 908.7029763 905.5025969 1314.812602 1335.453753 1274.501483 0.94628047 0.608173038 0.842015967 1.098924331 0.762875694 0.71298699 0.710475907 1.03162893 1.047824401 1 10.31571734 -7.494171933 21.6318082 0.976300703 0.820820506 0.239627921 0.141523502 80.64526413 60771.81046 0.02416874 0.02631422 3.21E-08 7.494171933 -0.155480197 SQDKS(ph)LLDGEGPQAVGGQDVAFSR ddPTM_HeLa_Curcumin_4h_R1 1 SQDKSLLDGEGPQAVGGQDVAFSR 24 1 A1X283 A1X283 SH3PXD2B SH3 and PX domain-containing protein 2B 1 0 S(0.248)QDKS(0.752)LLDGEGPQAVGGQDVAFSR 59.07 0.0029194 10406000 894.36 877 634.36 514.17 664.4 1706.7 1984.9 1436.1 742.05 820.09 TRUE FALSE FALSE 823.5704623 952.8039722 657.8699396 512.0425008 656.4774639 1352.711182 2040.590952 1873.960279 660.6489715 848.5880665 0.970518553 1.122810949 0.775252405 0.603405258 0.773611473 1.594072831 2.404689663 2.208327401 0.778527294 1 9.72892058 -4.98506804 3.1831274 0.940115252 2.302773219 0.924587789 0.1650501 0.047818059 0.997323483 0.024665072 0.081266422 1.03E-05 4.98506804 1.362657967 up ADGYEPPVQES(ph)V ddPTM_HeLa_Curcumin_4h_R1 2 ADGYEPPVQESV 12 0 P61247;H0Y9Y4;D6RAT0;D6R9B6 P61247 RPS3A 40S ribosomal protein S3a 1 0 ADGYEPPVQES(1)V;ADGYEPPVQES(1)V ; 136.38 0.0016501 77017000 7278 6396.8 6519.2 6795.2 6576.8 8084.6 6076.3 5244.1 7508.1 6418.4 TRUE FALSE FALSE 6701.93862 6949.710888 6760.807287 6767.083263 6498.375955 6407.762828 6246.784624 6843.001949 6684.480214 6641.438922 1.009109426 1.046416442 1.017973268 1.018918241 0.978459041 0.964815442 0.940576989 1.030349301 1.006480718 1 12.69728013 -5.704133563 6.730091213 1.009952222 0.974523219 0.344914569 0.024412223 0.191661207 17.49210023 0.003477074 0.006958985 1.98E-06 5.704133563 -0.035429003 ADGYVLEGK ddPTM_HeLa_Curcumin_4h_R1 2 ADGYVLEGK 9 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 0 ; ; 118.18 0.0014916 25634000 12032.4 9545 10364.7 11170.4 11016.1 11656.9 9581.5 9357.1 11624.9 10279.6 FALSE FALSE TRUE 11080.02284 10370.02727 10748.8249 11124.17984 10884.7402 9239.12754 9850.331103 12210.03672 10349.67755 10636.81533 1.041667313 0.974918426 1.010530367 1.045818649 1.023308186 0.868599035 0.926060178 1.147903421 0.973005287 1 13.37677865 ADHGEPIGR ddPTM_HeLa_Curcumin_4h_R1 6 ADHGEPIGR 9 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 0 ;;;;; ;;;;; 114.89 0.00057486 224717000 29156.2 27922.2 27504.8 25175.9 26312.3 30875.4 23496.8 22610.3 27508.3 28697.8 FALSE FALSE TRUE 26848.456 30335.67055 28524.15208 25071.7288 25998.54301 24471.494 24156.05697 29504.07638 24490.70831 29695.04641 0.904139217 1.021573434 0.960569372 0.844306772 0.875517844 0.824093475 0.813470928 0.99356896 0.82474053 1 14.85793467 -6.269134044 23.99214933 0.960056998 0.864775344 0.188800904 0.069445404 265.7362531 828572.373 0.008944796 0.013829989 5.38E-07 6.269134044 -0.095281654 AMS(ph)TTSISSPQPGK ddPTM_HeLa_Curcumin_4h_R1 3 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 0 AMS(0.959)T(0.038)T(0.002)S(0.002)ISSPQPGK;AMS(0.909)T(0.059)T(0.018)S(0.013)IS(0.001)SPQPGK;AMS(0.973)T(0.025)T(0.001)S(0.001)ISSPQPGK ;; 126.09 0.0014954 77652000 6112 3895.3 5622.9 5606.5 5759.7 20233.3 35000.8 20560.7 6846.7 6007.5 TRUE FALSE FALSE 5628.228751 4231.992375 5831.28962 5583.301789 5691.019339 16036.6855 35982.82825 26829.56278 6095.63414 6216.260178 0.905404309 0.680793959 0.938070392 0.898176979 0.915505332 2.57979638 5.788500999 4.316029576 0.980595079 1 12.60183117 -4.969482883 3.241751314 0.932433304 5.045112609 0.950072277 0.376880713 0.03055959 0.661214303 0.047958357 0.159560542 1.07E-05 4.969482883 4.112679305 up ADIEISGPK ddPTM_HeLa_Curcumin_4h_R1 1 ADIEISGPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 114.89 0.0020241 3160800 3340.6 2788.9 2913.8 3171.6 3198.4 3616 2693.1 2866.1 3396.6 2914.3 FALSE FALSE TRUE 3076.187985 3029.960089 3021.787991 3158.47676 3160.261169 2866.000839 2768.661138 3739.960696 3024.001478 3015.571708 1.02010109 1.004771361 1.002061395 1.047389041 1.047980773 0.950400493 0.918121473 1.240216137 1.002795413 1 11.55821583 -4.24785855 24.98644647 1.005443272 1.240216294 0.781777665 0.038061893 839.9529922 1545347.139 0.005273926 0.142834274 5.65E-05 4.24785855 0.234773022 NSPTFKS(ph)FEEKVENLK ddPTM_HeLa_Curcumin_4h_R1 2 NSPTFKSFEEKVENLK 16 2 H0YC42;P55327-2;P55327;P55327-3;P55327-4;P55327-7;P55327-5;P55327-6;E5RK35 H0YC42 TPD52 Tumor protein D52 1 0 NS(0.001)PT(0.266)FKS(0.733)FEEKVENLK;NSPT(0.13)FKS(0.87)FEEKVENLK ; 84.208 0.0070311 463650000 5406.4 2627.4 3533.3 3541.3 3131.4 17515.1 26939 19083.3 5004.8 3654.8 TRUE FALSE FALSE 4978.477735 2854.500749 3664.247206 3526.647039 3094.0601 13882.27082 27694.83584 24901.71032 4455.785961 3781.804028 1.316429328 0.754798696 0.968915147 0.932530351 0.818143954 3.670806504 7.323181115 6.584611507 1.178217044 1 11.88485889 -4.968941393 2.788667752 1.075357514 7.004209642 0.983109669 0.311289952 0.022811205 0.355310643 0.046220575 0.162832908 1.07E-05 4.968941393 5.928852129 up ADIKS(ph)PSLDVTVPEAELNLETPEISVGGK ddPTM_HeLa_Curcumin_4h_R1 2 ADIKSPSLDVTVPEAELNLETPEISVGGK 29 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 ADIKS(0.477)PS(0.178)LDVT(0.346)VPEAELNLETPEISVGGK;ADIKS(0.794)PS(0.199)LDVT(0.007)VPEAELNLETPEISVGGK ; 102.19 4.04E-09 134161900 4631.04 3303.57 3611.68 4277.98 3815.27 7965.69 9288.54 7437.37 4452.55 3132.96 TRUE FALSE FALSE 4264.488297 3589.11587 3745.532038 4260.278852 3769.775397 6313.516102 9549.151434 9704.989876 3964.116405 3241.830127 1.315457051 1.107126447 1.155375788 1.314158573 1.162854082 1.947516019 2.945605124 2.993676256 1.222802013 1 11.66259278 -4.94199997 2.146892084 1.159051991 3.050417974 0.980548899 0.100258448 0.037156734 0.331124741 0.019040179 0.079864614 1.14E-05 4.94199997 1.891365983 up ADILEDKDGK ddPTM_HeLa_Curcumin_4h_R1 1 ADILEDKDGK 10 1 A0A087X0X3;P52272-2;P52272;M0R2T0;M0QYQ7;M0R0N3;M0R019;M0QZM1 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 0 90.827 0.016095 38607000 2918.7 2625.6 3296.2 2795.3 3048.5 3828.1 2923.8 2324.9 3319.5 3112.5 FALSE FALSE TRUE 2687.681815 2852.545165 3418.360072 2783.733789 3012.148629 3034.108908 3005.833959 3033.751307 2955.359155 3220.659143 0.834512966 0.885702286 1.061385238 0.864336667 0.935258435 0.942077001 0.933297758 0.941965968 0.917625562 1 11.65314027 ADINTK(ac)WAATR ddPTM_HeLa_Curcumin_4h_R1 2 ADINTKWAATR 11 1 P50914;E7EPB3 P50914 RPL14 60S ribosomal protein L14 0 1 ; ADINTK(1)WAATR;ADINTK(1)WAATR 113.22 0.0034772 11955900 2531.8 3456.3 3090 2794.2 2021.89 2916.2 2666.1 1730.75 3428.6 4255.5 FALSE TRUE FALSE 2331.405358 3755.047171 3204.518118 2782.638341 1997.780282 2311.347248 2740.903591 2258.447708 3052.491158 4403.378308 0.529458337 0.852765061 0.727740815 0.631932609 0.453692629 0.524903173 0.622454715 0.512889775 0.693215741 1 12.10439508 -13.52287875 0.252825812 3.609100984 0.555327161 0.20085895 0.144112659 22.01191933 0.291708665 28.70396062 0.067857353 3.00E-14 13.52287875 -3.053773823 ADIPVKS(ph)SPQAAVPYK ddPTM_HeLa_Curcumin_4h_R1 1 ADIPVKSSPQAAVPYK 16 1 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 0 ADIPVKS(0.5)S(0.5)PQAAVPYK 58.32 0.019475 15631000 1956.4 1491.6 1310.6 1427.2 1924 2507.8 2273.2 1268.3 1585.2 1341.7 TRUE FALSE FALSE 1801.548876 1620.527258 1359.171989 1421.294625 1901.057557 1987.654011 2336.979874 1654.998831 1411.307526 1388.323975 1.297642991 1.167254392 0.979002029 1.023748527 1.369318394 1.431693212 1.683310175 1.192084024 1.01655489 1 10.43912855 -5.61875105 4.881595353 1.125689706 1.451852366 0.553406397 0.146043369 0.140244235 5.626437972 0.023487134 0.047958693 2.41E-06 5.61875105 0.32616266 ADIPVKS(ph)SPQAAVPYKK ddPTM_HeLa_Curcumin_4h_R1 1 ADIPVKSSPQAAVPYKK 17 2 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 0 ADIPVKS(0.5)S(0.5)PQAAVPY(0.001)KK 70.529 0.013713 24651000 2285 1557.9 1867.4 1974 1881.7 2799.9 2529.3 1214.6 2296.2 1864.4 TRUE FALSE FALSE 2104.139839 1692.557934 1936.607487 1965.832111 1859.261956 2219.169179 2600.265351 1584.925949 2044.312605 1929.187761 1.09068691 0.877342252 1.003846036 1.018994704 0.963753759 1.150312698 1.34785499 0.821550904 1.059675292 1 10.91377785 -5.248386567 24.36863965 1.021622262 1.130701086 0.096034018 0.132018233 871.1353579 1626340.266 0.017240358 0.043641961 5.64E-06 5.248386567 0.109078824 ADIPVKSS(ph)PQAAVPYKK ddPTM_HeLa_Curcumin_4h_R1 1 ADIPVKSSPQAAVPYKK 17 2 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 0 ADIPVKS(0.19)S(0.81)PQAAVPYKK 86.539 0.0043718 27628000 1833.3 1154.1 1328.8 1579.9 1141.9 2216.5 1790.8 869.27 1568.2 1211.3 TRUE FALSE FALSE 1688.192371 1253.855261 1378.046497 1573.362792 1128.283588 1756.772915 1841.045028 1134.306421 1396.172383 1253.392585 1.346898323 1.000369139 1.099453207 1.25528331 0.900183711 1.401614256 1.468849466 0.904988936 1.113914667 1 10.29162265 -9.659887574 1.509877337 1.000167586 1.201996535 0.025039314 0.193995077 0.667244097 2.740396329 0.133590728 0.030144264 2.19E-10 9.659887574 0.201828948 ADKDYHFKVDNDENEHQLSLR ddPTM_HeLa_Curcumin_4h_R1 2 ADKDYHFKVDNDENEHQLSLR 21 2 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 0 0 ; ; 40.723 0.015183 653490000 15012.4 10873.3 10906.2 11831.7 9616.3 19191.6 11569.2 11940.4 18867.9 14936.3 FALSE FALSE TRUE 13824.1527 11813.1396 11310.39337 11782.74356 9501.631903 15211.04583 11893.80062 15580.97299 16798.13858 15455.33531 0.894458284 0.764340557 0.731811581 0.762373855 0.614780056 0.984193841 0.769559532 1.008129081 1.086882829 1 13.91581733 -7.810911308 1.287365044 0.971557599 0.800408052 0.353998732 0.1173101 0.338701965 1.172510613 0.025124628 0.023214073 1.55E-08 7.810911308 -0.171149546 ADLDVSGPK ddPTM_HeLa_Curcumin_4h_R1 1 ADLDVSGPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 150.36 3.23E-06 23628000 7634.6 6207.5 6665.9 7409.3 7268.8 7858.1 6832.4 6605.6 6793.9 5815.3 FALSE FALSE TRUE 7030.313354 6744.04864 6912.944118 7378.64228 7182.124307 6228.241481 7024.098756 8619.617032 6048.626167 6017.381242 1.168334375 1.120761402 1.148829339 1.226221504 1.193563116 1.035041861 1.167301601 1.432453203 1.005192446 1 12.55492005 -13.52287875 0.094656142 0.39731565 1.332891945 0.463125072 0.088432387 101.4054244 0.722157124 12.36464114 0.93921375 3.00E-14 13.52287875 0.935576295 ADLGVSGPK ddPTM_HeLa_Curcumin_4h_R1 1 ADLGVSGPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 94.692 0.015476 2933000 3776.3 2730.3 3240.2 2952.8 3338.7 4499.8 2989.6 3458.1 4110.8 3227.2 FALSE FALSE TRUE 3477.40187 2966.294966 3360.284662 2940.582096 3298.888183 3566.490757 3073.48013 4512.458771 3659.855525 3339.34496 1.041342512 0.888286476 1.006270602 0.880586502 0.987884817 1.068021064 0.920384137 1.351300577 1.095980071 1 11.70534942 -4.253707907 24.74780246 0.997158591 1.351300774 0.710125744 0.069464392 316.3591085 1012611.761 0.008595661 0.122778621 5.58E-05 4.253707907 0.354142183 ADLINNLGTIAK ddPTM_HeLa_Curcumin_4h_R1 2 ADLINNLGTIAK 12 0 P08238;Q58FF8;P07900;P07900-2;Q14568 P08238;P07900 HSP90AB1;HSP90AB2P;HSP90AA1;HSP90AA2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2;Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2 0 0 ; ; 234.3 1.15E-38 14209500 6961.6 5310.8 5994.8 5891.1 5515.8 6891.3 5644.84 5995.6 6591.3 6055.3 FALSE FALSE TRUE 6410.582014 5769.841888 6216.972562 5866.724189 5450.027687 5461.966699 5803.219018 7823.63084 5868.250881 6265.721224 1.023119572 0.920858379 0.992219784 0.936320653 0.869816497 0.871721946 0.92618532 1.24864011 0.936564311 1 12.61326487 -7.279349611 23.8638569 1.010917577 0.957444316 0 0.104685071 1072.870925 1429505.6 0.016869269 0.019316456 5.26E-08 7.279349611 -0.053473261 ADLLQREEEEEEEEDQEGDRETTIR ddPTM_HeLa_Curcumin_4h_R1 1 ADLLQREEEEEEEEDQEGDRETTIR 25 2 A0A0B4J2E5;Q15269 A0A0B4J2E5 PWP2 Periodic tryptophan protein 2 homolog 0 0 91.067 7.30E-06 8971100 782.44 537.26 591.44 782.19 533.35 695.19 598.24 478.29 687.12 835.19 FALSE FALSE TRUE 720.5090484 583.6983604 613.3592867 778.953505 526.9901496 550.9997576 615.0250043 624.1184192 611.7446551 864.2127903 0.833717178 0.675410462 0.709731785 0.901344569 0.60979212 0.637574176 0.711659225 0.722181419 0.707863459 1 9.755242773 -8.082273062 0.440244795 1.016481373 0.682888105 0 0.117354388 0.427989245 0.2002528 0.059027493 0.031991402 8.27E-09 8.082273062 -0.333593268 ADLNQGIGEPQS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 4 ADLNQGIGEPQSPSR 15 0 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 0 ADLNQGIGEPQS(0.992)PS(0.008)R;ADLNQGIGEPQS(1)PSR;ADLNQGIGEPQS(1)PSR;ADLNQGIGEPQS(0.979)PS(0.021)R ;;; 209.19 8.16E-10 203124800 7348.7 6216 6829.2 6723.1 7053.3 8874.5 7066.4 2714.21 7189.9 5600.5 TRUE FALSE FALSE 6767.042641 6753.283342 7082.29616 6695.281594 6969.194004 7033.828664 7264.664166 3541.760134 6401.185958 5795.116958 1.167714593 1.165340301 1.222114448 1.155331573 1.202597645 1.213750941 1.253583701 0.611162839 1.104582704 1 12.50062206 -1.356316928 14.70970392 1.104737901 0.005511496 0 0.179493043 0 0 0.022454924 0 0.044023348 1.356316928 -1.099226405 ADMTASGSPDY(ph)GQPHK ddPTM_HeLa_Curcumin_4h_R1 1 ADMTASGSPDYGQPHK 16 0 A0A0A0MSR4;Q01543 A0A0A0MSR4 FLI1 Friend leukemia integration 1 transcription factor 1 0 ADMT(0.036)AS(0.025)GS(0.105)PDY(0.835)GQPHK 52.599 0.016675 6869700 7595.8 6557 6262.6 7203.7 6997.5 6450.4 6215.3 4563 7943.9 7190.5 TRUE FALSE FALSE 6994.584415 7123.757863 6494.697465 7173.892998 6914.059383 5112.514329 6389.68459 5954.237695 7072.474045 7440.36934 0.940085646 0.957446806 0.872899875 0.964185065 0.929262926 0.687131794 0.858785942 0.800261038 0.950554162 1 12.86115852 -5.402447079 0.39113867 0.986026769 0.729738341 0.527117702 0.061497875 1.411461109 0.270157614 0.020150397 0.149667185 3.96E-06 5.402447079 -0.256288427 APVSSTESVIQSNT(ph)PTPPPSQPLNETAEEESR ddPTM_HeLa_Curcumin_4h_R1 2 APVSSTESVIQSNTPTPPPSQPLNETAEEESR 32 0 B5MBZ0;Q9HC35;Q9HC35-2 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 0 APVSSTESVIQS(0.363)NT(0.502)PT(0.134)PPPS(0.001)QPLNETAEEESR;APVSSTESVIQS(0.004)NT(0.903)PT(0.092)PPPSQPLNETAEEESR ; 153.76 6.82E-14 16537900 1845.68 1330.34 1455.58 1308.27 1070.38 931.86 843.62 411.083 1953.26 1613.73 TRUE FALSE FALSE 1699.59248 1445.328662 1509.525075 1302.856725 1057.616418 738.5817318 867.2897067 536.4203143 1738.992265 1669.806997 1.01783768 0.865566298 0.904011708 0.780243901 0.633376444 0.442315629 0.51939518 0.321246896 1.041433092 1 10.70546564 -5.682767594 0.709432507 1.011007541 0.341438244 0.957795818 0.050420931 0.10583266 0.090695486 0.008897329 0.039213599 2.08E-06 5.682767594 -0.669569297 down ADNSSDS(ph)PTTLK ddPTM_HeLa_Curcumin_4h_R1 2 ADNSSDSPTTLK 12 0 A0A2R8YH03;Q5VWN6;J3KPH3 A0A2R8YH03 FAM208B Protein FAM208B 1 0 ADNSSDS(0.998)PT(0.001)TLK;ADNS(0.011)S(0.005)DS(0.907)PT(0.068)T(0.009)LK ; 166.79 0.0001235 18806300 3968.5 3231.1 3086.3 2968.2 2901.5 4815 3463.5 1670.7 3557.2 2844.1 TRUE FALSE FALSE 3654.389037 3510.381886 3200.680993 2955.918375 2866.901508 3816.314724 3560.676488 2180.088739 3166.98406 2942.932263 1.241750985 1.192817766 1.087582284 1.004412644 0.974164966 1.296772872 1.209907728 0.740787943 1.076132162 1 11.52303862 -6.529594153 24.32635285 1.124056454 1.062548941 0.056339498 0.150852252 414.5055993 1501527.703 0.0256452 0.036324984 2.95E-07 6.529594153 -0.061507513 ADPSLLGFSVNAS(ph)SER ddPTM_HeLa_Curcumin_4h_R1 2 ADPSLLGFSVNASSER 16 0 Q6Y7W6-4;Q6Y7W6-5;Q6Y7W6;I1E4Y6;Q6Y7W6-3 Q6Y7W6-4 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 0 ADPSLLGFSVNAS(0.962)S(0.038)ER;ADPSLLGFSVNAS(0.759)S(0.241)ER ; 143.43 0.0003805 14288300 1386.82 877.47 1293.86 1408.38 1186.08 1631.64 1792.54 1392.18 1443.33 1019.84 TRUE FALSE FALSE 1277.051734 953.3145969 1341.81159 1402.552497 1171.936771 1293.219472 1842.833848 1816.649273 1285.00031 1055.279364 1.210155128 0.903376517 1.271522628 1.329081705 1.110546468 1.225475941 1.746299521 1.721486589 1.217687329 1 10.04340926 -4.813272329 3.938498893 1.119405205 1.74529744 0.780052958 0.121855475 0.069158825 2.172515623 0.018477868 0.065444643 1.54E-05 4.813272329 0.625892236 ADQDRLDLEER ddPTM_HeLa_Curcumin_4h_R1 1 ADQDRLDLEER 11 1 G8JLG1;Q14683 G8JLG1 SMC1A Structural maintenance of chromosomes protein;Structural maintenance of chromosomes protein 1A 0 0 84.821 0.019743 19308000 4269.4 3372.5 3743.8 4285.8 3700.2 4634.5 4168.4 3279.6 3878.1 3734.7 FALSE FALSE TRUE 3931.472485 3664.003872 3882.548521 4268.066495 3656.077532 3673.252458 4285.354085 4279.534943 3452.682133 3864.480547 1.017335302 0.948123254 1.004675395 1.104434721 0.946072179 0.950516483 1.108908179 1.107402377 0.893440164 1 11.91605879 -4.742609537 24.98211643 1.003157271 1.108155391 0.408549115 0.056185316 153.4037552 203521.9558 0.005935093 0.022129452 1.81E-05 4.742609537 0.10499812 ADQEQQDPLEY(ph)LQSDEEDDEKR ddPTM_HeLa_Curcumin_4h_R1 1 ADQEQQDPLEYLQSDEEDDEKR 22 1 Q7RTV3 Q7RTV3 ZNF367 Zinc finger protein 367 1 0 ADQEQQDPLEY(0.969)LQS(0.031)DEEDDEKR 89.756 0.00030365 19226000 2181.6 1801 2256.6 2949.7 3389.6 1392 1048.4 813.62 2818.1 2277.7 TRUE FALSE FALSE 2008.924058 1956.670415 2340.231581 2937.494923 3349.181234 1103.283509 1077.815282 1061.688993 2508.961481 2356.849905 0.852376748 0.83020578 0.992948925 1.246364869 1.421041376 0.468117849 0.457311804 0.450469497 1.064540205 1 11.20264417 -5.155709702 11.11764913 0.978494723 0.456577527 0.693753869 0.177102433 0.284658132 28.50624962 0.027264126 0.069578642 6.99E-06 5.155709702 -0.521917196 ADQEQQDPLEYLQS(ph)DEEDDEKR ddPTM_HeLa_Curcumin_4h_R1 1 ADQEQQDPLEYLQSDEEDDEKR 22 1 Q7RTV3 Q7RTV3 ZNF367 Zinc finger protein 367 1 0 ADQEQQDPLEYLQS(1)DEEDDEKR 131.5 8.22E-06 17158000 1943.8 1917.5 2057.5 2993.2 2937.5 959.62 687.16 451.09 2624.5 2432.2 TRUE FALSE FALSE 1789.946179 2083.240156 2133.75276 2980.814931 2902.472231 760.5839949 706.4398602 588.6252644 2336.598916 2516.718769 0.711222168 0.827760408 0.847831226 1.184405253 1.153276348 0.302212549 0.280698769 0.233885991 0.928430679 1 11.2973283 -5.242703791 22.75201721 0.898111819 0.273108642 0.823260651 0.142555811 100.7452723 122341.3078 0.024567237 0.06246011 5.72E-06 5.242703791 -0.625003177 ADRDQS(ph)PFSK ddPTM_HeLa_Curcumin_4h_R1 2 ADRDQSPFSK 10 1 Q13427;E9PG73 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 0 ADRDQS(1)PFSK;ADRDQS(0.998)PFS(0.002)K ; 85.536 0.010938 280080000 18620 16163.2 16649.6 17255.9 18116.1 21236.2 17259.1 15183.5 18943.7 15963.2 TRUE FALSE FALSE 17146.20735 17560.27499 17266.64882 17184.49966 17900.07734 16831.57274 17743.3439 19812.87925 16865.6235 16517.92001 1.03803671 1.063104493 1.045328274 1.040354938 1.083676233 1.018988633 1.074187542 1.199477854 1.021050077 1 14.01174441 -1.000000109 0.885552216 1.027256003 78.56963932 0.786305973 0.024497377 287.2068415 0.639270272 0.004424024 44989.41727 0.099999975 1.000000109 77.54238332 ADREVQAEQPSSS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 ADREVQAEQPSSSSPR 16 1 A0A1W2PP04;Q9Y388 A0A1W2PP04 RBMX2 "RNA-binding motif protein, X-linked 2" 1 0 ADREVQAEQPSS(0.001)S(0.656)S(0.344)PR;ADREVQAEQPS(0.004)S(0.02)S(0.812)S(0.164)PR ; 143.99 0.0001652 65468000 4428.6 3362.8 3379.1 3883.7 3055.3 4651.2 3121.2 2199.3 4116.9 3146.7 TRUE FALSE FALSE 4078.071637 3653.465448 3504.332419 3867.630278 3018.867543 3686.48869 3208.772472 2869.856446 3665.28637 3256.047591 1.252460698 1.122055297 1.076253439 1.187829775 0.92715707 1.132197423 0.985480827 0.88139266 1.125685749 1 11.66890607 -3.371399296 0.657103283 1.118996748 0.265901817 0.415562551 0.085439671 7.787634701 0.998849905 0.018490038 6.550807079 0.000425207 3.371399296 -0.85309493 ADREVQAEQPSSSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 ADREVQAEQPSSSSPR 16 1 A0A1W2PP04;Q9Y388 A0A1W2PP04 RBMX2 "RNA-binding motif protein, X-linked 2" 1 0 ADREVQAEQPSS(0.001)S(0.242)S(0.757)PR;ADREVQAEQPSS(0.004)S(0.313)S(0.683)PR ; 136.33 0.00018431 63808000 5857.6 3951.9 4119.7 4340.1 4574.2 6954.8 4425.2 2974.5 4910.7 4749.5 TRUE FALSE FALSE 5393.964779 4293.484627 4272.379706 4322.141816 4519.655653 5512.296083 4549.359202 3881.411357 4372.008496 4914.544771 1.097551254 0.873628144 0.869333764 0.879459241 0.919648892 1.12162903 0.9256929 0.789780445 0.889605996 1 12.26284207 -7.259362104 24.99342223 1.046065871 0.917433887 0.07089127 0.096432008 167.9550967 2020809.571 0.015006902 0.017893131 5.50E-08 7.259362104 -0.128631984 ADS(ph)DSEDKGEESKPK ddPTM_HeLa_Curcumin_4h_R1 1 ADSDSEDKGEESKPK 15 2 C9JWS9;K7ELA4;B5MD17;J3KS05;P83916 C9JWS9 CBX1 Chromobox protein homolog 1 1 0 ADS(0.991)DS(0.009)EDKGEESKPK 88.19 0.0066109 9127100 2017.2 2018.5 1714.8 1847.9 1849.2 2174.5 1539.6 1734.2 2064.7 1981 TRUE FALSE FALSE 1857.536491 2192.970146 1778.351996 1840.253879 1827.149498 1723.484188 1582.797032 2262.949597 1838.207576 2049.839603 0.906186264 1.06982524 0.867556659 0.897755062 0.89136218 0.84078978 0.772156529 1.103964229 0.896756787 1 11.00129531 ADS(ph)FSEGDDLSQGHLAEPCFLR ddPTM_HeLa_Curcumin_4h_R1 1 ADSFSEGDDLSQGHLAEPCFLR 22 0 A0A1B0GTT1;A0A1B0GVM0;Q9BUH8 A0A1B0GTT1 BEGAIN Brain-enriched guanylate kinase-associated protein 1 0 ADS(0.951)FS(0.049)EGDDLSQGHLAEPCFLR 109.19 1.43E-05 11878000 617.34 577.84 504.65 610.82 850.28 1111 890.75 307.18 750.69 497.41 TRUE FALSE FALSE 568.4768876 627.7859148 523.3527729 608.2925887 840.1409663 880.5660764 915.7420477 400.8377679 668.3411851 514.6949605 1.104492819 1.219724231 1.01682125 1.181850679 1.632308514 1.710850395 1.779193732 0.778787046 1.298519 1 9.007573847 -5.899122838 4.84588549 1.065166969 1.511826848 0.250059927 0.274074462 0.158353225 6.232127186 0.036874719 0.068085682 1.26E-06 5.899122838 0.446659879 GLQVVEHACS(ph)VTSLMMGETMPS(ph)IT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 GLQVVEHACSVTSLMMGETMPSITK 25 0 Q02252-2;Q02252 Q02252-2 ALDH6A1 "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial" 3 0 GLQVVEHACS(0.334)VT(0.334)S(0.334)LMMGET(0.494)MPS(0.559)IT(0.945)K 44.105 0.0082328 0 1253.6 1627.9 1560.6 1595.3 1051.7 272.59 520.09 734.8 1778.6 2057.1 TRUE FALSE FALSE 1154.376237 1768.608422 1618.437209 1588.699071 1039.159164 216.0517613 534.6823256 958.8371374 1583.49203 2128.584072 0.542321185 0.830884927 0.760335112 0.746364258 0.488192681 0.101500225 0.251191547 0.450457724 0.743918011 1 11.05567836 -5.610640138 3.051063343 0.779563095 0.266429524 0.746627132 0.132106318 0.12780481 2.387747297 0.027263184 0.059332639 2.45E-06 5.610640138 -0.513133571 down ADS(ph)PLEQPEGSPLTQDDR ddPTM_HeLa_Curcumin_4h_R1 1 ADSPLEQPEGSPLTQDDR 18 0 P09603-3;P09603-2;P09603 P09603-3 CSF1 Macrophage colony-stimulating factor 1;Processed macrophage colony-stimulating factor 1 1 0 ADS(0.999)PLEQPEGS(0.001)PLTQDDR 84.195 0.0049209 3631600 959.33 715.11 921.66 1010.6 840.43 626.42 352.8 393.18 1032.8 886.4 TRUE FALSE FALSE 883.3980182 776.9209219 955.8175304 1006.418405 830.4084212 496.4934308 362.6986185 513.058772 919.5044239 917.202334 0.963144102 0.847055108 1.042101066 1.097269782 0.905371029 0.541312873 0.395440139 0.559373601 1.002509904 1 9.841096216 -5.26889255 3.466053983 0.983564558 0.47541116 0.907051859 0.07110252 0.046746181 1.199296904 0.009956223 0.025725951 5.38E-06 5.26889255 -0.508153398 ADS(ph)PVNGLPK ddPTM_HeLa_Curcumin_4h_R1 1 ADSPVNGLPK 10 0 Q96S94;Q96S94-3;A0A0A0MSF3 Q96S94 CCNL2 Cyclin-L2 1 0 ADS(1)PVNGLPK 95.273 0.015714 71134000 11819 10442 10301 10840 10834 12180 9082.8 8551.3 11420 9746.8 TRUE FALSE FALSE 10883.51368 11344.55995 10682.76412 10795.14695 10704.81163 9653.730703 9337.638923 11158.552 10167.25457 10085.50057 1.079124789 1.124838561 1.05922002 1.07036303 1.06140608 0.957189049 0.92584784 1.106395456 1.008106092 1 13.29999507 -5.2743374 24.53529577 1.050502903 0.989414487 0.196332122 0.054814299 732.6978842 1393775.669 0.008210092 0.018475933 5.32E-06 5.2743374 -0.061088416 ADSEGSNSGGT(ph)WPK ddPTM_HeLa_Curcumin_4h_R1 1 ADSEGSNSGGTWPK 14 0 Q8TDM6-4;Q8TDM6;Q8TDM6-3 Q8TDM6-4 DLG5 Disks large homolog 5 1 0 ADSEGSNSGGT(0.999)WPK 142.54 0.00040515 0 1118.6 976.8 1139.7 1164 1533 1211.7 609.92 384.17 1017.9 968.43 TRUE FALSE FALSE 1030.06163 1061.230239 1181.938285 1159.183676 1514.719976 960.3797613 627.0327137 501.3016645 906.2389167 1002.08287 1.027920604 1.059024429 1.179481577 1.156774266 1.511571569 0.958383573 0.6257294 0.500259688 0.904355262 1 9.968786106 -4.769319126 3.632247382 1.074426193 0.53717043 0.652582346 0.158473739 0.107382344 2.976745274 0.022923329 0.088895262 1.70E-05 4.769319126 -0.537255763 ASS(ph)LSES(ph)SPPK ddPTM_HeLa_Curcumin_4h_R1 1 ASSLSESSPPK 11 0 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;F8VRN8;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 2 0 AS(0.01)S(0.99)LS(0.24)ES(0.715)S(0.045)PPK 132.56 0.0058738 55577000 4911.8 3580.3 3679.2 3491.9 3968.9 9646.5 14362 9793.7 4259.5 3548.5 TRUE FALSE FALSE 4523.025847 3889.765178 3815.554389 3477.451443 3921.57346 7645.707162 14764.95907 12779.75405 3792.243507 3671.810111 1.231824553 1.059359025 1.03914807 0.947067342 1.068021859 2.08227194 4.021166297 3.480505162 1.032799462 1 11.84227574 -4.939905033 3.015961019 1.091471328 3.767512876 0.974142854 0.173723722 0.026392102 0.482022051 0.025342106 0.089021887 1.15E-05 4.939905033 2.676041548 up ADSEQPSK(ac)RPR ddPTM_HeLa_Curcumin_4h_R1 2 ADSEQPSKRPR 11 2 Q9Y3Z3-3;Q9Y3Z3-4;Q9Y3Z3;A0A2R8Y7R5;A0A2R8Y755;A0A2R8Y586;A0A2R8YF51;A0A2R8Y5D2;A0A2R8YCS7 Q9Y3Z3-3 SAMHD1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 0 1 ; ADSEQPSK(1)RPR;ADSEQPSK(1)RPR 89.805 0.0051311 3357000 3043.9 2573.9 2711.8 2200.18 2302.2 4000.6 3191.9 2420.9 2536.6 2191.4 FALSE TRUE FALSE 2802.972103 2796.376447 2812.301694 2191.076238 2274.747769 3170.830464 3281.456123 3159.021266 2258.341326 2267.550987 1.236123077 1.233214363 1.240237468 0.966274298 1.003173813 1.398350239 1.447136643 1.39314233 0.995938499 1 11.14691928 -1 0.320322154 1.094000822 4.786511983 0.456435896 0.131062346 39.93931399 0.509109801 0.04958676 87.62708872 0.1 1 3.692511161 S(ph)PSPLVSLQAVK ddPTM_HeLa_Curcumin_4h_R1 1 SPSPLVSLQAVK 12 0 Q9UPZ3-2;Q9UPZ3 Q9UPZ3-2 HPS5 Hermansky-Pudlak syndrome 5 protein 1 0 S(0.782)PS(0.218)PLVSLQAVK 117.27 0.0038447 25928000 1877.4 1305 1333.4 1247.9 1008.9 739.32 410.85 355.92 1272.4 1396.7 TRUE FALSE FALSE 1728.801809 1417.798385 1382.816977 1242.73652 996.8695264 585.9766981 422.3773453 464.4383695 1132.820903 1445.235221 1.196207914 0.981015661 0.956811014 0.859885299 0.689762823 0.405454205 0.292255087 0.321358325 0.783831508 1 10.4970886 -5.574354505 0.953985035 1.087094068 0.253821775 0.857149868 0.112535885 0.102399604 0.169493326 0.01394743 0.054539524 2.66E-06 5.574354505 -0.833272294 down KSLSDS(ph)ESDDSKSK ddPTM_HeLa_Curcumin_4h_R1 1 KSLSDSESDDSKSK 14 2 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 0 KS(0.004)LS(0.364)DS(0.604)ES(0.027)DDSKSK 85.054 0.010461 75784000 3877.3 3667.6 2997.1 2969.1 1870.3 3367.5 1645.4 1053.7 3581.8 3855.2 TRUE FALSE FALSE 3570.407614 3984.611001 3108.175163 2956.814651 1847.997894 2669.04254 1691.565496 1374.968279 3188.885501 3989.167913 0.895025652 0.998857679 0.779153756 0.741210878 0.463253975 0.669072498 0.424039683 0.344675458 0.79938613 1 11.96187214 -5.563214116 0.514115093 0.975539736 0.285206872 0.799805753 0.099375152 0.355623658 0.135094664 0.019496537 0.118408142 2.73E-06 5.563214116 -0.690332865 down ADSLLAVVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 ADSLLAVVKR 10 1 Q15424-2;Q15424;Q15424-4;Q15424-3;Q14151 Q15424-2;Q14151 SAFB;SAFB2 Scaffold attachment factor B1;Scaffold attachment factor B2 0 1 ; ADSLLAVVK(1)R;ADSLLAVVK(1)R 177.3 4.49E-16 31156800 5541.2 5238.7 5120.6 4731.5 5479.3 7022.2 5675 6107.9 5100.4 4855.3 FALSE TRUE FALSE 5102.608173 5691.509885 5310.373941 4711.922307 5413.962926 5565.716563 5834.225227 7970.170593 4540.898881 5024.021314 1.015642223 1.132859423 1.056996698 0.937878646 1.077615438 1.107821049 1.161266018 1.586412576 0.903837503 1 12.29462687 ADT(ph)PGPEDGGVK ddPTM_HeLa_Curcumin_4h_R1 2 ADTPGPEDGGVK 12 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 0 ADT(1)PGPEDGGVK;ADT(1)PGPEDGGVK ; 161.25 0.00054938 27064000 8754.4 7562.6 8076.6 8166 9118 8228.4 7334.6 2860.7 8630 6844 TRUE FALSE FALSE 8061.480002 8216.277446 8375.925901 8132.211256 9009.273805 6521.737087 7540.389136 3732.914261 7683.310591 7081.828491 1.138333131 1.160191532 1.182734927 1.148320842 1.272167748 0.92091147 1.06475173 0.527111644 1.084933164 1 12.78990619 -4.014422777 1.825266917 1.096045726 8.51E-15 0.77128091 0.094518969 0.776930386 1.486375105 0.014729896 1.803789243 9.67E-05 4.014422777 -1.096045726 ADTGHAFLAK(ac)PPAR ddPTM_HeLa_Curcumin_4h_R1 2 ADTGHAFLAKPPAR 14 1 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 0 1 ; ADTGHAFLAK(1)PPAR;ADTGHAFLAK(1)PPAR 106.54 0.0031211 11199700 4971 3987.2 4393.6 4571.2 3905.8 6583.3 5321.5 2513.6 5200 4395.4 FALSE TRUE FALSE 4577.540105 4331.835801 4556.430681 4552.285586 3859.225886 5217.849371 5470.806968 3279.985069 4629.57301 4548.139823 1.006464243 0.952441211 1.001822912 1.000911529 0.848528417 1.147249112 1.202866926 0.721170676 1.017904724 1 12.15106089 -2.683121095 8.498170714 0.998361673 0.999329687 0 0.128783601 0 0 0.015113316 0 0.002074335 2.683121095 0.000968014 ADTQTYQPYNK ddPTM_HeLa_Curcumin_4h_R1 1 ADTQTYQPYNK 11 0 P84090 P84090 ERH Enhancer of rudimentary homolog 0 0 120.63 0.0020208 1788800 989.7 805.48 958.89 804.33 1037.9 1359.3 1086.4 925.78 925.12 864.15 FALSE FALSE TRUE 911.3642007 875.1021021 994.4273069 801.0018956 1025.52372 1077.365858 1116.88146 1208.04606 823.6366505 894.1791482 1.019218803 0.978665297 1.11211194 0.895795767 1.146888431 1.204865781 1.249057823 1.351011218 0.921109212 1 9.804420093 -5.191417949 1.384951754 1.008024227 1.316723136 0.787233132 0.065565624 0.134229936 0.464549439 0.008099379 0.035161088 6.44E-06 5.191417949 0.308698908 ADTS(ph)LNNCEGAAGSTSEK ddPTM_HeLa_Curcumin_4h_R1 2 ADTSLNNCEGAAGSTSEK 18 0 O76080;Q5QPB1 O76080 ZFAND5 AN1-type zinc finger protein 5 1 0 ADT(0.021)S(0.979)LNNCEGAAGSTSEK;ADT(0.042)S(0.958)LNNCEGAAGSTSEK ; 153.82 5.96E-05 17156000 3405.1 3103.05 2852.37 3267.2 3211.6 4906.6 3962.4 2667.99 3167.28 3327.7 TRUE FALSE FALSE 3135.582742 3371.263815 2958.081341 3253.681192 3173.303768 3888.915851 4073.57428 3481.447869 2819.837308 3443.337327 0.910623167 0.979068704 0.859073933 0.944920838 0.921577954 1.1294031 1.183030848 1.011067908 0.818925664 1 11.74959181 -5.258898779 24.99134771 0.947850091 1.115353651 0.599714384 0.067775134 105.7198335 1039934.407 0.008080244 0.019575809 5.51E-06 5.258898779 0.167503561 ADVDISGPK ddPTM_HeLa_Curcumin_4h_R1 1 ADVDISGPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 164.96 1.74E-11 23070000 12315 10174 10668 11598 11522 13037 10604 10435 11617 9125.4 FALSE FALSE TRUE 11340.25476 11053.39523 11063.36546 11550.01055 11384.60768 10332.97924 10901.5197 13616.58346 10342.64416 9442.506971 1.20097923 1.170599636 1.171655525 1.223193225 1.205676386 1.094304645 1.154515399 1.442051725 1.0953282 1 13.20495423 -13.52287874 0.193010059 0.063323103 1.244096025 0.347146226 0.088209369 33.7709779 0.402670877 11.87198154 0.092522218 3.00E-14 13.52287874 1.180772922 ADVLEAHEAEAEEPEAGKS(ph)EAEDDEDEVDDLPSSR ddPTM_HeLa_Curcumin_4h_R1 2 ADVLEAHEAEAEEPEAGKSEAEDDEDEVDDLPSSR 35 1 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 0 ADVLEAHEAEAEEPEAGKS(1)EAEDDEDEVDDLPSSR;ADVLEAHEAEAEEPEAGKS(0.999)EAEDDEDEVDDLPSSR ; 97.592 1.84E-11 132445000 8597 5261.8 6516.7 6793.5 7510.7 7904.1 5821.2 4510 6889.4 6102.3 TRUE FALSE FALSE 7916.538378 5716.606546 6758.214635 6765.390297 7421.139808 6264.700562 5984.527205 5885.078239 6133.650056 6314.354471 1.25373677 0.90533507 1.070293831 1.071430235 1.175280837 0.992136344 0.947765481 0.932015817 0.971381965 1 12.62441954 -5.065644654 5.008945412 1.101461047 0.945533639 0.139434485 0.098237087 0.216152716 10.61531838 0.016009049 0.043249423 8.60E-06 5.065644654 -0.155927408 ADVQLFMDDDS(ph)YS(ph)HHSGLEYADPEK ddPTM_HeLa_Curcumin_4h_R1 1 ADVQLFMDDDSYSHHSGLEYADPEK 25 0 E9PCT3;P51636-3;P51636 E9PCT3 CAV2 Caveolin;Caveolin-2 2 0 ADVQLFMDDDS(0.552)Y(0.519)S(0.877)HHS(0.051)GLEY(0.001)ADPEK 69.619 0.001053 0 1520.9 1225.3 1216.4 1681.6 1982.7 1749.6 752.77 293.93 1600.2 1108.1 TRUE FALSE FALSE 1400.51916 1331.209472 1261.480854 1674.641985 1959.057597 1386.713238 773.8907002 383.5479039 1424.662064 1146.606393 1.221447193 1.160999521 1.100186483 1.460520363 1.708570273 1.209406512 0.674940158 0.334507034 1.242503158 1 10.16315451 -4.601067379 3.284934179 1.184539588 0.382889622 0.69455359 0.201286221 0.125061319 2.565369236 0.033080378 0.16827109 2.51E-05 4.601067379 -0.801649965 HLT(ph)PEPDIVASTK ddPTM_HeLa_Curcumin_4h_R1 3 HLTPEPDIVASTK 13 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 HLT(1)PEPDIVASTK;HLT(1)PEPDIVASTK;HLT(1)PEPDIVASTK ;; 180.06 0.00014461 70813000 24767.9 21217.7 19308.7 18740.2 13375.4 10876.6 7108.4 3490.75 24456.5 21706.5 TRUE FALSE FALSE 22807.49458 23051.66344 20024.29741 18662.65802 13215.90709 8620.670555 7307.842573 4555.063606 21773.68314 22460.79926 1.015435574 1.026306463 0.891522033 0.830899106 0.588398789 0.383809608 0.325359863 0.202800602 0.969408207 1 14.45512165 -5.541967314 0.963283665 1.01094923 0.214585196 0.98943134 0.031129285 0.034966596 0.058632479 0.004500387 0.01807051 2.87E-06 5.541967314 -0.796364034 down ADVVVSGPK ddPTM_HeLa_Curcumin_4h_R1 2 ADVVVSGPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 147.51 7.05E-06 9751200 15486 12240.2 13587 13930.7 13714.7 16859.5 12923.4 14428.2 15715.3 13143 FALSE FALSE TRUE 14260.26676 13298.18835 14090.54617 13873.05845 13551.16116 13362.64965 13285.99582 18827.29176 13991.37091 13599.71827 1.048570748 0.977828223 1.036091034 1.020098959 0.99642955 0.982568123 0.976931695 1.384388366 1.028798585 1 13.73128914 -4.257920657 24.99920801 1.014285533 1.384388506 0.953971688 0.02479665 56.08189826 398423.0451 0.003893806 0.038069619 5.52E-05 4.257920657 0.370102973 ADYDTLS(ph)LR ddPTM_HeLa_Curcumin_4h_R1 2 ADYDTLSLR 9 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PJR7;E9PRW6;E9PQ15 Q9Y446 PKP3 Plakophilin-3 1 0 ADYDT(0.009)LS(0.991)LR;ADYDT(0.001)LS(0.999)LR ; 103.08 0.011384 28122000 3983.3 3255 4304.9 4455.9 4501.9 8365.1 7843.3 6072.2 4186.6 4501.4 TRUE FALSE FALSE 3668.017602 3536.347696 4464.443381 4437.462666 4448.217783 6630.083966 8063.361889 7923.585827 3727.340454 4657.823315 0.78749608 0.759227531 0.958482767 0.952690209 0.954999252 1.423429683 1.731143786 1.701134906 0.800232255 1 12.1854402 -5.116002137 2.070276763 0.892858935 1.730907382 0.951436371 0.077608233 0.060009459 0.491650661 0.014105529 0.049802279 7.66E-06 5.116002137 0.838048447 ADYEIASK ddPTM_HeLa_Curcumin_4h_R1 2 ADYEIASK 8 0 Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383;A8MYV2;Q9NQ29-2;B8ZZ12;Q9NQ29;Q9NQ29-3 Q96HJ9-2;Q9NQ29 LUC7L2;LUC7L Putative RNA-binding protein Luc7-like 2;Putative RNA-binding protein Luc7-like 1 0 0 ; ; 120.07 0.0027177 6937400 6247.2 4888.7 5910 5534.8 6197.8 7717.2 5493.1 5147.8 6707.4 5728.4 FALSE FALSE TRUE 5752.727528 5311.257444 6129.029799 5511.898464 6123.895283 6116.565729 5647.221602 6717.340522 5971.615001 5927.461474 0.970521285 0.896042508 1.034005843 0.929891909 1.033139618 1.031903076 0.952721773 1.133257559 1.007448978 1 12.53319867 -4.254019856 24.69481525 0.983791338 1.133257644 0.502746342 0.044542467 452.5062097 1506057.679 0.005646111 0.078181384 5.57E-05 4.254019856 0.149466306 AES(ph)GDSLGSEDRDLLYSIDAYR ddPTM_HeLa_Curcumin_4h_R1 3 AESGDSLGSEDRDLLYSIDAYR 22 1 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 0 AES(0.375)GDS(0.312)LGS(0.312)EDRDLLYSIDAYR;AES(0.659)GDS(0.17)LGS(0.17)EDRDLLYSIDAYR;AES(0.953)GDS(0.025)LGS(0.022)EDRDLLYSIDAYR ;; 85.571 0.00025178 53164000 2779.33 1772.13 2108.35 2260.76 2018.12 4265.6 4796.8 3868.96 2598.56 2007.4 TRUE FALSE FALSE 2559.343098 1925.305021 2186.487306 2251.405574 1994.055237 3380.866477 4931.385298 5048.588093 2313.504469 2077.157001 1.232137531 0.926894318 1.052634589 1.083888013 0.959992546 1.627641279 2.374103304 2.430527925 1.113784114 1 11.02039455 -4.917610304 2.588383926 1.083392209 2.441668574 0.971618242 0.091763304 0.037590534 0.49787485 0.016174452 0.062384488 1.21E-05 4.917610304 1.358276365 up AEAAASALADADADLEER ddPTM_HeLa_Curcumin_4h_R1 2 AEAAASALADADADLEER 18 0 M0R1T5;O43633 M0R1T5 CHMP2A Charged multivesicular body protein 2a 0 0 ; ; 172.91 5.18E-05 9750800 4388.5 3404.4 3271.7 3332.7 3981.3 4477.9 3702.6 3104.9 4200.8 3660.6 FALSE FALSE TRUE 4041.145594 3698.661166 3392.95208 3318.91017 3933.825598 3549.133064 3806.484991 4051.569717 3739.98275 3787.805578 1.066883057 0.976465421 0.895756662 0.87620922 1.03855003 0.936989238 1.00493146 1.069635079 0.987374529 1 11.88714657 -7.131663806 6.870955068 1.03147875 0.966634749 0.10133685 0.059609935 0.31035477 16.10555911 0.010230684 0.012556714 7.38E-08 7.131663806 -0.064844001 AEAAVVAVAEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 AEAAVVAVAEKR 12 1 A0A087WYP2;Q8IZQ5 A0A087WYP2 C11orf31;SELH Selenoprotein H 0 1 ; AEAAVVAVAEK(1)R;AEAAVVAVAEK(1)R 167.18 5.59E-07 20552600 5784 4708.2 4590 5569.2 4495.9 7571.5 5882.6 6397.7 5784.4 4996.5 FALSE TRUE FALSE 5326.190297 5115.155829 4760.109438 5546.156126 4442.289329 6001.085552 6047.649924 8348.329279 5149.865792 5170.128003 1.030185383 0.989367348 0.920694697 1.072730912 0.859222311 1.160722819 1.169729245 1.614723905 0.996080907 1 12.33598428 -3.947862319 1.22676448 1.002494411 2.320252704 0.877985078 0.069755615 0.623023983 0.471225144 0.009331732 1.248050663 0.000112755 3.947862319 1.317758293 AEADKIYSFTDNAPS(ph)PSIGGSSR ddPTM_HeLa_Curcumin_4h_R1 1 AEADKIYSFTDNAPSPSIGGSSR 23 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 0 AEADKIYSFTDNAPS(0.957)PS(0.042)IGGSSR 129.22 3.23E-06 41120000 1673.5 1486.2 1628.8 1790 1452.3 1684.3 1580.3 523.35 1922.3 1526.9 TRUE FALSE FALSE 1541.040709 1614.660506 1689.164761 1782.593454 1434.982271 1334.957194 1624.638965 682.9170058 1711.428499 1579.959661 0.975367123 1.02196312 1.069118916 1.12825251 0.908239815 0.844931188 1.028278762 0.432236988 1.08321025 1 10.62567201 -4.259193607 24.96067584 0.992191116 0.43223679 0.821786021 0.07998819 58.00739704 644679.8289 0.010415541 0.092661633 5.51E-05 4.259193607 -0.559954326 AEADKIYSFTDNAPSPSIGGSS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 AEADKIYSFTDNAPSPSIGGSSR 23 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 0 AEADKIYSFTDNAPS(0.246)PS(0.04)IGGS(0.061)S(0.653)R 103.42 0.00010708 0 1496.1 1060.2 1196.8 1504.5 1317.7 1068.4 1102.9 540.21 1491 1060.4 TRUE FALSE FALSE 1377.682106 1151.838964 1241.154461 1498.274778 1301.987288 846.8017967 1133.844406 704.9175422 1327.44103 1097.248821 1.255578571 1.049751835 1.131151328 1.365483151 1.186592561 0.771750017 1.033352129 0.64244092 1.209790345 1 10.099675 -5.263795428 24.94925221 1.14126418 0.837598125 0.589538612 0.133890526 131.5602066 1393159.012 0.020750402 0.048567745 5.45E-06 5.263795428 -0.303666055 AEAEAGS(ph)PRPDPR ddPTM_HeLa_Curcumin_4h_R1 3 AEAEAGSPRPDPR 13 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 1 0 AEAEAGS(1)PRPDPR;AEAEAGS(1)PRPDPR;AEAEAGS(1)PRPDPR ;; 101.75 0.0026851 428619000 23615.3 20300.7 21432.4 23396.7 21112.6 30402.9 23847.2 20929.5 24746.8 21509.7 TRUE FALSE FALSE 21746.12409 22055.40205 22226.7036 23299.89065 20860.84603 24096.99583 24516.28825 27310.8082 22032.13795 22257.16047 0.977039462 0.990935123 0.998631592 1.046849201 0.937264484 1.082662627 1.101501168 1.227057164 0.989889882 1 14.44198193 -4.27443257 1.012747233 0.990458246 1.344493458 0.847970574 0.030986427 0.453097069 0.361539197 0.00436587 0.172759043 5.32E-05 4.27443257 0.354035211 AEAES(ph)DALPDDTVIESEALPSDIAAEAR ddPTM_HeLa_Curcumin_4h_R1 1 AEAESDALPDDTVIESEALPSDIAAEAR 28 0 Q9GZR7-2;Q9GZR7;G3V529;A0A1W2PRR2;F5GYL3 Q9GZR7-2 DDX24 ATP-dependent RNA helicase DDX24 1 0 AEAES(0.987)DALPDDT(0.013)VIESEALPSDIAAEAR 55.779 0.0047106 0 172.68 198.84 300.79 261.33 286.98 372.08 175.45 353.7 308.53 274.82 TRUE FALSE FALSE 159.0121958 216.0268436 311.937542 260.2486857 283.5579509 294.9064138 180.3726548 461.5415018 274.6850309 284.3699745 0.559173647 0.759668259 1.09694261 0.915176386 0.997144482 1.03705187 0.634288677 1.623031765 0.965942453 1 8.151625335 -6.768975321 24.75119708 0.783603243 1.022480402 0.149331256 0.256960014 212.2424933 697093.0168 0.042167902 0.056029245 1.70E-07 6.768975321 0.238877159 AEAGAGS(ph)ATEFQFR ddPTM_HeLa_Curcumin_4h_R1 2 AEAGAGSATEFQFR 14 0 P46783;Q9NQ39 P46783 RPS10;RPS10P5 40S ribosomal protein S10;Putative 40S ribosomal protein S10-like 1 0 AEAGAGS(0.954)AT(0.046)EFQFR;AEAGAGS(0.958)AT(0.042)EFQFR ; 241.76 1.18E-28 116630000 1923.28 1525.84 2044.8 2014.69 1825.39 2642.79 893.87 546.45 2059.69 1758.68 TRUE FALSE FALSE 1771.050359 1657.726811 2120.582087 2006.353747 1803.623416 2094.645564 918.9495865 713.0600895 1833.74716 1819.793999 0.973214748 0.910942014 1.165286888 1.102516959 0.991114059 1.151034438 0.504974512 0.391835609 1.00766744 1 10.82955943 -4.693173761 6.014297802 1.011393712 0.4291758 0.890355711 0.082457319 0.045635154 2.939709518 0.011580725 0.04431281 2.03E-05 4.693173761 -0.582217912 AEAGDNLGALVR ddPTM_HeLa_Curcumin_4h_R1 1 AEAGDNLGALVR 12 0 P49411 P49411 TUFM "Elongation factor Tu, mitochondrial" 0 0 121.36 0.00099529 4098700 585.21 623.34 572.66 368.45 708.05 638.07 510.89 391.53 557.1 480.23 FALSE FALSE TRUE 538.890011 677.2187321 593.8832834 366.9254515 699.6069662 505.7270895 525.2241984 510.9056946 495.9875238 496.9179568 1.084464757 1.362838116 1.195133473 0.73840248 1.407892302 1.01772754 1.056963612 1.028148989 0.998127592 1 8.956863866 -8.420300247 1.341635699 1.015677093 1.111914228 0.057342594 0.178200391 0.933129548 3.385599461 0.047794255 0.032845829 3.80E-09 8.420300247 0.096237135 AEAGEQPGT(ph)AER ddPTM_HeLa_Curcumin_4h_R1 1 AEAGEQPGTAER 12 0 P56182 P56182 RRP1 Ribosomal RNA processing protein 1 homolog A 1 0 AEAGEQPGT(1)AER 119.96 0.010347 8946900 1378.4 1969.4 1535 1534.1 1209.8 2874.3 2768.2 2364.7 1796 1656 TRUE FALSE FALSE 1269.298186 2139.626161 1591.88845 1527.752301 1195.373925 2278.13778 2845.868242 3085.686144 1598.983293 1713.545877 0.740743626 1.248654144 0.929002527 0.89157362 0.697602522 1.329487474 1.660806565 1.800760742 0.933142973 1 10.7427691 -4.952034537 2.743028202 0.89858375 1.747132193 0.828411762 0.147995809 0.080602195 1.210334366 0.022961154 0.082932904 1.12E-05 4.952034537 0.848548443 AEAGEQPGTAER ddPTM_HeLa_Curcumin_4h_R1 1 AEAGEQPGTAER 12 0 P56182 P56182 RRP1 Ribosomal RNA processing protein 1 homolog A 0 0 136.5 0.00024736 463260 59.919 0 153.06 0 0 129.73 0 0 209.86 0 FALSE FALSE TRUE 55.17634792 0 158.7325382 0 0 102.8225356 0 0 186.838883 0 0 FKMPS(ph)FGVSAPGK ddPTM_HeLa_Curcumin_4h_R1 2 FKMPSFGVSAPGK 13 1 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 FKMPS(0.998)FGVS(0.002)APGK;FKMPS(0.86)FGVS(0.14)APGK ; 69.422 0.015975 47058000 4606.8 2481.9 3684.7 3237.4 3311.4 10014.1 18455.7 12134.8 4042.8 2596.2 TRUE FALSE FALSE 4242.166919 2696.424377 3821.258223 3224.004497 3271.913718 7937.062778 18973.51727 15834.64466 3599.314955 2686.417757 1.579116617 1.003724894 1.422436333 1.20011286 1.217946728 2.954515454 7.062757541 5.894334423 1.339819522 1 11.39146796 -4.912772806 3.316870156 1.272905972 6.501832425 0.969837207 0.363115162 0.026760404 0.580473448 0.053104803 0.184515045 1.22E-05 4.912772806 5.228926453 up AVS(ph)EEQQPALK ddPTM_HeLa_Curcumin_4h_R1 1 AVSEEQQPALK 11 0 Q5STZ8;Q8NE71;Q8NE71-2;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 0 AVS(1)EEQQPALK 131.69 0.0025916 9090300 1872.5 1334.7 1560.9 1678.2 1348.5 4109.8 5502.1 4515.6 1445.2 1434.2 TRUE FALSE FALSE 1724.289649 1450.065521 1618.748327 1671.256053 1332.420018 3257.381153 5656.474118 5892.385653 1286.665176 1484.038343 1.161890228 0.977107854 1.090772576 1.126154227 0.897833957 2.194944065 3.811541759 3.970507689 0.86700265 1 10.53531265 -4.908238153 2.432045885 1.064777367 4.002703271 0.989041435 0.120261665 0.0180831 0.21005854 0.01589768 0.064203166 1.24E-05 4.908238153 2.937925904 up AET(ph)LELSDLYVSDK ddPTM_HeLa_Curcumin_4h_R1 1 AETLELSDLYVSDK 14 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 0 AET(0.988)LELS(0.012)DLYVSDK 156.2 3.33E-06 0 705.46 647.84 445.17 633.89 731.41 921.1 1266.4 920.69 811.58 450.4 TRUE FALSE FALSE 649.6220966 703.8364029 461.6683918 631.2671311 722.6884134 730.0534771 1301.931776 1201.404143 722.5517045 466.0513665 1.393885188 1.510212079 0.990595512 1.354501191 1.550662578 1.566465694 2.793537085 2.577836327 1.550369243 1 8.864345162 -4.885251092 2.134646749 1.22947751 2.75244505 0.833080048 0.231858489 0.084438844 0.739849378 0.033558655 0.152264475 1.30E-05 4.885251092 1.522967539 up LEDVKNS(ph)PTFK ddPTM_HeLa_Curcumin_4h_R1 1 LEDVKNSPTFK 11 1 H0YC42;P55327-2;P55327;P55327-3 H0YC42 TPD52 Tumor protein D52 1 0 LEDVKNS(0.964)PT(0.036)FK 69.345 0.017881 79349000 5019.8 4968.9 4468.4 5183.6 5017.7 8210.4 9473.7 7736.8 4939.9 4411.7 TRUE FALSE FALSE 4622.477533 5398.389575 4634.002835 5162.151637 4957.867205 6507.47049 9739.506525 10095.7147 4398.005329 4565.006247 1.012589531 1.182559077 1.015114237 1.130809326 1.086059238 1.425511848 2.133514392 2.211544554 0.963417155 1 12.15640112 -4.87533938 1.998124768 1.031551099 2.258430403 0.976630185 0.068264758 0.033833633 0.255665272 0.010019793 0.048524132 1.33E-05 4.87533938 1.226879304 up AEAPPLEREDSGT(ph)FSLGK ddPTM_HeLa_Curcumin_4h_R1 1 AEAPPLEREDSGTFSLGK 18 1 G5E9Q4;O75569 G5E9Q4 PRKRA Interferon-inducible double-stranded RNA-dependent protein kinase activator A 1 0 AEAPPLEREDS(0.48)GT(0.514)FS(0.006)LGK 105.17 0.0098082 37393000 910.74 794.38 951.99 824.88 971.1 2405.8 2018.9 1763.7 1285.5 1078.5 TRUE FALSE FALSE 838.653968 863.0426675 987.2715869 821.4668651 959.5202667 1906.809961 2075.5449 2301.444011 1144.483866 1115.977795 0.751497003 0.773351111 0.884669562 0.736096067 0.859802293 1.708645073 1.859844264 2.06226685 1.025543583 1 10.12409261 -5.175644566 3.102776653 0.85665915 1.938739101 0.952501531 0.104751837 0.042376335 0.786357256 0.01719459 0.048961979 6.67E-06 5.175644566 1.082079951 AEAS(ph)PNDTAGAR ddPTM_HeLa_Curcumin_4h_R1 1 AEASPNDTAGAR 12 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 0 AEAS(0.641)PNDT(0.359)AGAR 98.654 0.010053 10491000 2063.5 1799.4 1815.6 2021.4 1744.8 2783.7 1952.8 1676.5 2094.3 1650.3 TRUE FALSE FALSE 1900.171798 1954.932118 1882.887733 2013.035982 1723.9944 2206.329241 2007.590312 2187.657132 1864.56053 1707.647802 1.112742215 1.144809905 1.102620652 1.178835577 1.009572581 1.292028273 1.175646588 1.281093871 1.091888226 1 10.73779474 -1 0.081310893 0.866174448 1.879838239 0.439586958 0.06977598 90.25648154 0.538918287 1.020596322 10.32061477 0.1 1 1.013663791 AVT(ph)PVPTKTEEVSNLK ddPTM_HeLa_Curcumin_4h_R1 1 AVTPVPTKTEEVSNLK 16 1 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 0 AVT(0.999)PVPT(0.001)KTEEVSNLK 127.29 0.0046842 66387000 3758.1 3070.3 2767.1 2851.6 1960.6 1381.3 792.75 518.87 3745.7 2908.6 TRUE FALSE FALSE 3460.642419 3335.683051 2869.65116 2839.800835 1937.221126 1094.80281 814.9924314 677.0710744 3334.806081 3009.673634 1.149839764 1.108320521 0.953475861 0.943557734 0.643664849 0.363761305 0.270790966 0.224964949 1.108029138 1 11.55539134 -5.51492973 1.23258008 1.072632164 0.219264768 0.981280556 0.04772044 0.057127336 0.165086787 0.010136176 0.034341234 3.06E-06 5.51492973 -0.853367396 down AEDGAT(ph)PSPSNET(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 2 0 AEDGAT(1)PSPS(0.001)NET(0.999)PK;AEDGAT(1)PSPS(0.002)NET(0.998)PK ; 202.79 7.97E-09 42799000 9734.7 9095 10019.9 8967.2 11568.3 12255.7 9770.9 3313.3 9242.4 7157.5 TRUE FALSE FALSE 8964.188223 9881.131273 10391.24631 8930.096102 11430.35558 9713.72967 10045.04516 4323.509917 8228.531843 7406.222592 1.210359007 1.334166122 1.403042668 1.205755835 1.543344861 1.31156329 1.356298036 0.583767212 1.111029508 1 12.85452219 -8.567847517 0.856340803 1.018172372 1.266320604 0.077580992 0.24324307 0.772345292 1.156331841 0.098491425 0.048987963 2.70E-09 8.567847517 0.248148232 AEDGATPS(ph)PS(ph)NETPKKK ddPTM_HeLa_Curcumin_4h_R1 1 AEDGATPSPSNETPKKK 17 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 2 0 AEDGAT(0.025)PS(0.827)PS(0.629)NET(0.519)PKKK 64.2 0.020168 11909000 3271.1 2321.2 2594.5 2528 3043 4025.2 3078.6 1307.4 3108.5 2517.1 TRUE FALSE FALSE 3012.188983 2521.834185 2690.654452 2517.539806 3006.714212 3190.328147 3164.97723 1706.020241 2767.505327 2604.569038 1.156501878 0.968234725 1.033051692 0.966585938 1.154399891 1.224896749 1.215163501 0.655010567 1.062557869 1 11.34682896 -7.257355405 23.85304906 1.07390366 1.047927975 0.006748136 0.158305976 1460.267976 8528935.333 0.026589432 0.031908169 5.53E-08 7.257355405 -0.025975685 AEDGATPS(ph)PSNET(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 2 0 AEDGAT(0.004)PS(0.983)PS(0.013)NET(1)PK 149.31 0.002029 17191000 10594 9582.5 10846 10012 12849 12504 11199 3219.5 10729 9044.6 TRUE FALSE FALSE 9755.473721 10410.7686 11247.9623 9970.572997 12695.78407 9910.529451 11513.2138 4201.110729 9552.055543 9358.899177 1.042374059 1.11239243 1.201846722 1.065357454 1.356546729 1.05894179 1.230188891 0.44888941 1.020638791 1 13.19212313 -4.252717953 24.74131301 1.077227338 0.448889038 0.751043239 0.113595557 416.0016914 1180101.502 0.01682587 0.265560687 5.59E-05 4.252717953 -0.6283383 AEDGATPS(ph)PSNET(ph)PKK ddPTM_HeLa_Curcumin_4h_R1 1 AEDGATPSPSNETPKK 16 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 2 0 AEDGAT(0.273)PS(0.706)PS(0.021)NET(1)PKK 135.57 1.21E-05 0 3355.4 2825.7 3169.6 2983.7 3815.1 4397.1 3406.9 999.4 3382.8 2695.5 TRUE FALSE FALSE 3089.816549 3069.940917 3287.068164 2971.35424 3769.607424 3485.091894 3502.488445 1304.112459 3011.715303 2789.168424 1.107791312 1.100665306 1.178511895 1.065319044 1.351516599 1.249509303 1.255746485 0.46756318 1.079789688 1 11.44561934 -8.868017343 0.772080575 1.001511633 1.118101621 0 0.229372434 2.040318642 2.298496365 0.133126641 0.045916286 1.36E-09 8.868017343 0.116589987 AEDGATPS(ph)PSNETPK ddPTM_HeLa_Curcumin_4h_R1 4 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 AEDGAT(0.001)PS(0.971)PS(0.028)NETPK;AEDGAT(0.027)PS(0.706)PS(0.013)NET(0.254)PK;AEDGAT(0.07)PS(0.922)PS(0.008)NETPK;AEDGAT(0.002)PS(0.896)PS(0.088)NET(0.014)PK ;;; 147.75 0.00046559 29557600 11134 10259.1 11336.3 10865.6 11289.1 11990.1 9313.8 5662.09 12397.8 11259 TRUE FALSE FALSE 10252.73215 11145.85089 11756.43325 10820.64103 11154.48486 9503.218104 9575.120161 7388.435176 11037.79236 11650.24941 0.880044005 0.956704916 1.009114297 0.928790504 0.957446013 0.815709413 0.821881131 0.634186867 0.947429705 1 13.50807322 -3.939613757 0.816904598 0.94933014 0.299665839 0.847664985 0.04195059 1.304711679 0.443803097 0.008493314 0.865177276 0.000114918 3.939613757 -0.649664301 AEDGATPS(ph)PSNETPKK ddPTM_HeLa_Curcumin_4h_R1 1 AEDGATPSPSNETPKK 16 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 AEDGAT(0.08)PS(0.891)PS(0.02)NET(0.009)PKK 101.54 0.0011756 98117000 2016.1 7803.5 1928.4 3852 2286 2821.2 2078 1072.1 2616.1 2563.7 TRUE FALSE FALSE 1856.523558 8477.999768 1999.8682 3836.061445 2258.740943 2236.051319 2136.303087 1398.978355 2329.120375 2652.788384 0.699838543 3.195882423 0.753874004 1.446048794 0.85145915 0.842906027 0.80530475 0.52736146 0.877989511 1 11.37329388 -4.851706868 1.353213837 1.072974941 0.574673502 0.075541365 0.706174863 1.558176749 4.569321743 0.107728285 0.789126769 1.41E-05 4.851706868 -0.498301439 AEDGATPSPSNET(ph)PK ddPTM_HeLa_Curcumin_4h_R1 12 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 AEDGAT(0.001)PS(0.017)PS(0.144)NET(0.838)PK;AEDGATPSPSNET(1)PK;AEDGATPSPS(0.04)NET(0.959)PK;AEDGATPS(0.002)PS(0.019)NET(0.978)PK;AEDGAT(0.001)PS(0.099)PS(0.132)NET(0.768)PK;AEDGATPS(0.025)PS(0.397)NET(0.578)PK;AEDGATPSPSNET(1)PK;AEDGAT(0.001)PS(0.309)PS(0.098)NET(0.593)PK;AEDGATPSPSNET(1)PK;AEDGATPSPSNET(1)PK;AEDGATPSPSNET(1)PK;AEDGAT(0.001)PS(0.012)PS(0.088)NET(0.899)PK ;;;;;;;;;;; 282.52 2.18E-63 15088008400 53115.4 85398.8 47242.6 61068.6 56363.6 58741.6 49566.3 17952.31 54488.4 50931.2 TRUE FALSE FALSE 48911.26004 92780.29174 48993.45231 60815.91431 55691.50088 46557.93001 50956.99698 23425.88668 48511.15884 52701.05541 0.928088815 1.760501588 0.929648409 1.153979059 1.056743559 0.88343449 0.966906575 0.444505077 0.920496914 1 15.68554423 -4.058540049 1.614867837 1.037821065 1.03E-10 0.366537577 0.244640906 1.622000399 2.660456732 0.034770446 3.065577448 8.74E-05 4.058540049 -1.037821064 AEDGATPSPSNET(ph)PKK ddPTM_HeLa_Curcumin_4h_R1 4 AEDGATPSPSNETPKK 16 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 AEDGATPSPS(0.017)NET(0.983)PKK;AEDGATPSPSNET(1)PKK;AEDGATPS(0.003)PS(0.284)NET(0.713)PKK;AEDGATPSPS(0.002)NET(0.998)PKK ;;; 234.36 3.05E-21 3210817300 18595.3 15754.4 17456 17646.4 19663.5 20601.6 16795.4 5944.1 19232.7 16544.7 TRUE FALSE FALSE 17123.46238 17116.14014 18102.93472 17573.38387 19429.02561 16328.59593 17266.63372 7756.428727 17122.92093 17119.62709 1.000224029 0.999796318 1.057437444 1.026505062 1.134897711 0.953793902 1.008587023 0.453072294 1.000192401 1 14.06336366 -4.26129065 8.088649072 1.012136076 0.448764593 0.931273663 0.046170855 0.016261925 13.44258182 0.006232657 0.049500021 5.48E-05 4.26129065 -0.563371484 AEDGATPSPSNET(ph)PKKK ddPTM_HeLa_Curcumin_4h_R1 4 AEDGATPSPSNETPKKK 17 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 AEDGATPS(0.001)PS(0.027)NET(0.972)PKKK;AEDGATPS(0.047)PS(0.206)NET(0.746)PKKK;AEDGAT(0.001)PS(0.13)PS(0.221)NET(0.648)PKKK;AEDGAT(0.001)PS(0.064)PS(0.074)NET(0.861)PKKK ;;; 80.975 0.0038676 2646500000 31421.5 23043.2 24787.7 28614.9 23573.2 34300.1 27036.4 8339.4 33588.9 28126.6 TRUE FALSE FALSE 28934.45512 25034.95153 25706.35397 28496.49913 23292.10499 27185.87262 27794.96862 10882.04467 29904.28171 29103.99726 0.99417461 0.860189455 0.883258535 0.979126643 0.800306047 0.934094117 0.955022376 0.373902065 1.027497407 1 14.82892969 -4.261351302 7.785152927 0.959983998 0.368488876 0.849577361 0.070503896 0.027412616 18.18548895 0.010591316 0.084546936 5.48E-05 4.261351302 -0.591495121 AEDGATPSPSNETPK ddPTM_HeLa_Curcumin_4h_R1 2 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 0 0 ; ; 283.47 1.30E-93 3321400 1184.54 897.05 928.35 1389.98 1193.69 1686.79 1341.94 2207.86 1499.31 1259.14 FALSE FALSE TRUE 1090.782409 974.5870048 962.7554677 1384.228631 1179.456026 1336.93074 1379.591225 2881.02635 1334.839444 1302.895021 0.837199 0.748016524 0.738935564 1.062425298 0.905257912 1.026123147 1.058865989 2.211249796 1.024518033 1 10.34750513 -4.190238544 2.480015096 0.909726362 2.657687826 0.924447175 0.110132035 0.138542376 0.882534441 0.016198551 0.548355773 6.45E-05 4.190238544 1.747961464 up AEDGENYDIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AEDGENYDIKK 11 1 E5RIW3;E5RJD8;O75347;E5RHG6;O75347-2;A0A494C144;E5RIX8 E5RIW3 TBCA Tubulin-specific chaperone A 0 1 ; AEDGENYDIK(1)K;AEDGENYDIK(1)K 230.95 9.04E-41 8805300 2965.1 4224.4 3093 2909.1 5869.7 7931.6 6159.1 5422.1 6609.2 2737.8 FALSE TRUE FALSE 2730.409206 4589.538312 3207.629301 2897.062915 5799.707661 6286.496752 6331.90777 7075.27333 5884.187295 2832.938346 0.963808199 1.6200629 1.132262305 1.022635356 2.047241045 2.219072914 2.235102567 2.497503463 2.077061544 1 11.46808349 -5.69079942 3.593639834 1.047681893 2.288901053 0.551377567 0.383050091 0.05644063 1.451469438 0.032254257 0.06643558 2.04E-06 5.69079942 1.24121916 AEDGS(ph)VIDYELIDQDAR ddPTM_HeLa_Curcumin_4h_R1 2 AEDGSVIDYELIDQDAR 17 0 P07355;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YNP5;H0YN28;H0YL33;H0YNA0;P07355-2 P07355;P07355-2 ANXA2 Annexin A2;Annexin 1 0 AEDGS(1)VIDYELIDQDAR;AEDGS(1)VIDYELIDQDAR ; 322.37 3.80E-113 51924000 4595.6 2872.5 3495.9 4086.2 4519 6251.8 3967.7 4867 4228.1 3010.8 TRUE FALSE FALSE 4231.853411 3120.7861 3625.461129 4069.292387 4465.113876 4955.106208 4079.022983 6350.925895 3764.288008 3115.425076 1.358355058 1.0017208 1.16371315 1.306175654 1.433227816 1.590507262 1.309299015 2.038542331 1.208274286 1 11.60521331 -1 0.334396388 1.12786231 9.068918338 0.695921036 0.159847466 24.82158299 0.314323787 0.054808152 124.0449933 0.1 1 7.941056029 AEDGSVIDYELIDQDAR ddPTM_HeLa_Curcumin_4h_R1 6 AEDGSVIDYELIDQDAR 17 0 P07355;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YNP5;H0YN28;H0YL33;H0YNA0;P07355-2 P07355;P07355-2 ANXA2 Annexin A2;Annexin 0 0 ;;;;; ;;;;; 296.97 1.25E-79 544705900 13063.9 9923.28 10590.72 12457.8 12596.66 16535.6 13515.6 15457.6 13859.5 9887.71 FALSE FALSE TRUE 12029.87853 10781.00411 10983.2214 12406.25292 12446.45306 13105.93017 13894.81136 20170.55108 12339.14752 10231.30719 1.175790963 1.053726949 1.07349151 1.212577503 1.216506633 1.280963412 1.358068046 1.971453961 1.206018674 1 13.32070286 -1 0.663237706 1.08681968 84.80180338 0.918224345 0.074297886 42.22007764 0.240617353 0.013362661 5214.53833 0.1 1 83.71498371 AEDK(ac)EWMPVTK ddPTM_HeLa_Curcumin_4h_R1 1 AEDKEWMPVTK 11 1 P15880;E9PQD7;E9PMM9;E9PPT0 P15880 RPS2 40S ribosomal protein S2 0 1 AEDK(1)EWMPVTK 101.56 0.0087486 1291400 912.95 930.32 929.36 746.88 1478.7 1644.8 1331.9 1190.2 1653 822.88 FALSE TRUE FALSE 840.6890442 1010.732715 963.8028991 743.7896085 1461.067468 1303.649939 1369.269529 1553.086501 1471.670036 851.4750188 0.9873326 1.187037427 1.131921522 0.873530746 1.715925231 1.531048957 1.608114741 1.823995381 1.728377232 1 9.733820393 -5.757088085 24.99993526 1.013925298 1.655458438 0.459369432 0.249944901 24.29962352 139609.2234 0.015506088 0.030170483 1.75E-06 5.757088085 0.64153314 AEDQTES(ph)SCESHR ddPTM_HeLa_Curcumin_4h_R1 2 AEDQTESSCESHR 13 0 Q9BU76 Q9BU76 MMTAG2 Multiple myeloma tumor-associated protein 2 1 0 AEDQT(0.001)ES(0.97)S(0.03)CESHR;AEDQTES(0.793)S(0.206)CESHR ; 127.32 0.00086539 25023000 5561.8 6821.3 5673.5 5768.1 5368 6403.4 3955.1 3695.6 6691 6602 TRUE FALSE FALSE 5121.577661 7410.902777 5883.764901 5744.233131 5303.990106 5075.262659 4066.069461 4822.371428 5957.01404 6831.419009 0.749709197 1.084826266 0.861280049 0.840855044 0.776411182 0.742929493 0.595201298 0.705910649 0.872002439 1 12.73796957 -5.454326146 1.24340697 0.895178326 0.650810018 0.566267814 0.089243001 0.353116431 1.025265376 0.017510589 0.062528041 3.51E-06 5.454326146 -0.244368308 AEDS(ph)DS(ph)EPEPEDNVR ddPTM_HeLa_Curcumin_4h_R1 2 AEDSDSEPEPEDNVR 15 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 2 0 AEDS(1)DS(1)EPEPEDNVR;AEDS(1)DS(1)EPEPEDNVR ; 138.73 0.0013361 22860200 3003.9 2824.5 3208.3 3160.9 2969.6 2445.2 2637.2 2530.5 3006.8 2878.1 TRUE FALSE FALSE 2766.138145 3068.637194 3327.20242 3147.821033 2934.18946 1938.037957 2711.192734 3302.037801 2676.961563 2978.113761 0.92882219 1.030396231 1.117218041 1.056984819 0.985250966 0.650760217 0.910372455 1.108768189 0.898878209 1 11.54018315 -5.470598628 24.99998772 0.990449229 0.879673867 0.152815693 0.118404185 486.1120821 232454.6844 0.016710127 0.037364687 3.38E-06 5.470598628 -0.110775362 AEDS(ph)DSEPEPEDNVR ddPTM_HeLa_Curcumin_4h_R1 1 AEDSDSEPEPEDNVR 15 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 0 AEDS(0.994)DS(0.006)EPEPEDNVR 290.37 1.89E-77 4121900 1503.2 1226.5 1255.8 1324.9 1245 1228.2 1466.5 1819.1 1292.6 1536.6 TRUE FALSE FALSE 1384.220134 1332.513195 1302.341053 1319.417915 1230.154188 973.4574753 1507.646043 2373.735216 1150.805014 1589.996736 0.870580488 0.838060334 0.819084105 0.829824292 0.773683468 0.612238663 0.948207005 1.492918295 0.723778224 1 10.63480809 -4.273420348 4.631723566 0.88183509 1.525007186 0.739202773 0.115218427 0.077171821 4.352801789 0.0174061 0.157085187 5.33E-05 4.273420348 0.643172096 AEEAPEK(ac)KR ddPTM_HeLa_Curcumin_4h_R1 1 AEEAPEKKR 9 2 Q96QC0 Q96QC0 PPP1R10 Serine/threonine-protein phosphatase 1 regulatory subunit 10 0 1 AEEAPEK(0.969)K(0.031)R 74.173 0.01462 710680 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 AEEDAALQAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AEEDAALQAKK 11 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;A0A2R8Y4M7;H0YA99;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 0 1 ; AEEDAALQAK(1)K;AEEDAALQAK(1)K 180.07 4.22E-12 8903700 6604.6 5532.7 5620.5 5428.1 5757.7 7798.3 7606.4 7034.4 5847.9 5391.1 FALSE TRUE FALSE 6081.838941 6010.921935 5828.800674 5405.63996 5689.043188 6180.844675 7819.815112 9179.156178 5206.400001 5578.440324 1.090240029 1.077527335 1.044879991 0.969023535 1.019826844 1.107987953 1.401792375 1.645469996 0.933307466 1 12.4456461 -4.58487956 1.98020738 1.038878598 1.668761748 0.948096925 0.048074006 0.061571494 0.392991444 0.006469414 0.055382393 2.60E-05 4.58487956 0.62988315 AEEDEILNRS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 6 AEEDEILNRSPR 12 1 P27824-3;P27824;P27824-2 P27824-3 CANX Calnexin 1 0 AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR;AEEDEILNRS(1)PR ;;;;; 172.58 0.0012963 5508512000 32141.4 31362.3 33503.8 54248.8 35148.5 51038.1 21562 12980.2 62606.1 45806.4 TRUE FALSE FALSE 29597.37427 34073.11746 34745.4803 54024.33284 34729.37709 40452.22274 22166.97169 16937.80323 55738.36746 47398.16899 0.6244413 0.71886991 0.733055328 1.139797887 0.732715584 0.853455389 0.467675696 0.357351425 1.175960351 1 15.53254371 -4.687923627 4.167775916 0.823571767 0.383098724 0.497807054 0.180475988 0.136283344 4.456174943 0.02423656 0.099393867 2.05E-05 4.687923627 -0.440473042 AEEFK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 AEEFKK 6 1 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 1 AEEFK(1)K 97.602 0.012822 3769100 2515.1 1900.9 1908.2 2055.9 2400.6 3568.7 2278.3 1906 2706.8 2124 FALSE TRUE FALSE 2316.027181 2065.205326 1978.919571 2047.393231 2371.974413 2828.511392 2342.222966 2487.130626 2409.870812 2197.808842 1.053789182 0.939665583 0.900405683 0.931561104 1.079245095 1.286968793 1.065708228 1.131641014 1.096487905 1 11.1018502 -5.522594668 24.99964532 1.00267959 1.157073022 0.515387549 0.075349287 6.502742837 572248.2228 0.010812283 0.021813895 3.00E-06 5.522594668 0.154393432 AEEILEK ddPTM_HeLa_Curcumin_4h_R1 2 AEEILEK 7 0 P62913;Q5VVC8;P62913-2 P62913 RPL11 60S ribosomal protein L11 0 0 ; ; 138.9 0.0044398 23335000 10533 7625.4 8868.9 8098.2 9380.2 12747.4 8875.6 8899.6 9113.6 7803.7 FALSE FALSE TRUE 9699.301936 8284.505598 9197.589236 8064.691794 9268.347241 10103.44555 9124.625449 11613.04707 8113.860881 8074.877994 1.201170091 1.025960467 1.139037549 0.998738532 1.147800282 1.251219592 1.130001649 1.438169974 1.004827675 1 12.97922475 -1.000000007 0.696948751 1.09048229 40.81981126 0.626551043 0.080982831 155.5343252 0.779378934 0.014986629 9638.322992 0.099999998 1.000000007 39.72932897 AEEKENDTVTIS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 AEEKENDTVTISPK 14 1 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 0 AEEKENDTVT(0.001)IS(0.999)PK;AEEKENDTVT(0.11)IS(0.89)PK;AEEKENDTVT(0.02)IS(0.98)PK;AEEKENDTVTIS(1)PK ;;; 138.28 0.0009093 148285000 17677.1 16001.1 16882.4 17343.8 18667 18994.5 16018.1 12246.44 17290.4 15432.7 TRUE FALSE FALSE 16277.93888 17384.16378 17508.0766 17272.03595 18444.40822 15054.82659 16467.52478 15980.32318 15393.68638 15968.98518 1.01934711 1.088620447 1.096380039 1.081598847 1.155014424 0.942754121 1.031219241 1.000710002 0.963973991 1 13.96298501 -3.283466973 13.95183369 1.03019945 1.048408138 0 0.063203246 0 0 0.008270477 0 0.000520635 3.283466973 0.018208688 AEELS(ph)PAALS(ph)PSLEPIR ddPTM_HeLa_Curcumin_4h_R1 2 AEELSPAALSPSLEPIR 17 0 A0A2R8YFR7;Q12774;A0A2R8YF49;A0A5F9ZGZ6 A0A2R8YFR7 ARHGEF5 Rho guanine nucleotide exchange factor 5 2 0 AEELS(1)PAALS(0.968)PS(0.032)LEPIR;AEELS(0.995)PAALS(0.985)PS(0.02)LEPIR ; 150.59 3.99E-09 5722800 6974.1 5538.1 5118.5 5594.7 5789.8 7544 5459.4 10157.3 6517.7 5240.8 TRUE FALSE FALSE 6422.092626 6016.788687 5308.196113 5571.550614 5720.760416 5979.289362 5612.576071 13254.21401 5802.724616 5422.91741 1.184250495 1.1095114 0.978845096 1.027408347 1.054923021 1.102596427 1.034973548 2.444111354 1.070037431 1 12.40485348 -4.260416977 24.99984623 1.075242767 2.444111787 0.981076262 0.057540413 10.55177983 257975.8388 0.010682533 0.087372379 5.49E-05 4.260416977 1.36886902 AEELSPAALS(ph)PSLEPIR ddPTM_HeLa_Curcumin_4h_R1 2 AEELSPAALSPSLEPIR 17 0 A0A2R8YFR7;Q12774;A0A2R8YF49;A0A5F9ZGZ6 A0A2R8YFR7 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 0 AEELSPAALS(0.917)PS(0.083)LEPIR;AEELS(0.001)PAALS(0.991)PS(0.008)LEPIR ; 184.87 3.68E-06 13662400 2943.9 2159.4 2226.76 2584.7 2470.47 3127.8 2313.6 6054.4 2775 2456.33 TRUE FALSE FALSE 2710.887209 2346.048914 2309.285684 2574.005196 2441.011259 2479.059022 2378.513389 7900.358689 2470.589443 2541.687285 1.066569922 0.923028151 0.908564047 1.012715141 0.960390082 0.975359572 0.935800955 3.10831263 0.972027305 1 11.31157082 -4.260345373 24.99989996 1.00209814 3.1083133 0.993445948 0.051989022 5.862801544 133957.2643 0.008477873 0.069649035 5.49E-05 4.260345373 2.10621516 AEENTDQAS(ph)PQEDYAGFER ddPTM_HeLa_Curcumin_4h_R1 2 AEENTDQASPQEDYAGFER 19 0 Q9NU22 Q9NU22 MDN1 Midasin 1 0 AEENTDQAS(1)PQEDYAGFER;AEENTDQAS(1)PQEDYAGFER ; 316.54 2.68E-115 66035000 3090.2 2353.3 2600.8 2539.9 2461.9 3176.9 2613 2017.32 2856.9 2910.9 TRUE FALSE FALSE 2845.607409 2556.708766 2697.187936 2529.390567 2432.54345 2517.975129 2686.313747 2632.391581 2543.505218 3012.053558 0.944739977 0.848825798 0.8954648 0.839756172 0.807602987 0.835966254 0.891854575 0.873952448 0.844442228 1 11.55653171 -7.492075927 0.985469001 0.986284494 0.850422671 0.075561156 0.052673978 0.147423417 0.290804847 0.006972146 0.007351625 3.22E-08 7.492075927 -0.135861823 LGVVEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 LGVVEKK 7 1 O15228-2;O15228 O15228-2 GNPAT Dihydroxyacetone phosphate acyltransferase 0 1 ; LGVVEK(1)K;LGVVEK(1)K 89.296 0.011359 16859900 10875.6 8370 9481.4 11082.5 8663 6556.9 3852.9 3052.3 12047.8 10099.2 FALSE TRUE FALSE 10014.78478 9093.465504 9832.789025 11036.64355 8559.699383 5196.925029 3961.002004 3982.932219 10726.18648 10450.14645 0.958339181 0.870175892 0.940923562 1.056123338 0.81909851 0.497306431 0.379037942 0.381136498 1.026414944 1 13.35123554 -5.284152576 2.323651133 0.972309353 0.383441673 0.960944388 0.050417667 0.038566167 0.403315928 0.007289484 0.020974131 5.20E-06 5.284152576 -0.58886768 down AEEQQLPPPLS(ph)PPS(ph)PSTPNHR ddPTM_HeLa_Curcumin_4h_R1 1 AEEQQLPPPLSPPSPSTPNHR 21 0 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9;J3KSW8;Q6WCQ1-3 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 2 0 AEEQQLPPPLS(0.999)PPS(0.732)PS(0.162)T(0.107)PNHR 70.718 0.0026369 0 1867.8 1698.5 1391.4 1545.6 2196.2 2388.5 1582.1 1818.1 1705.1 1759.5 TRUE FALSE FALSE 1719.961659 1845.310772 1442.966508 1539.204717 2170.011749 1893.098176 1626.489468 2372.43032 1518.054796 1820.642494 0.944700382 1.013549216 0.792558953 0.845418429 1.191893387 1.039796765 0.893360159 1.303073134 0.833801694 1 10.83023194 -4.253010799 24.26198453 0.970292572 1.303073391 0.456311653 0.113612299 481.0655192 1384717.05 0.014288063 0.215462273 5.58E-05 4.253010799 0.332780818 AEEQQLPPPLS(ph)PPSPSTPNHR ddPTM_HeLa_Curcumin_4h_R1 2 AEEQQLPPPLSPPSPSTPNHR 21 0 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9;J3KSW8;Q6WCQ1-3 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 AEEQQLPPPLS(0.946)PPS(0.019)PS(0.019)T(0.015)PNHR;AEEQQLPPPLS(0.949)PPS(0.008)PS(0.007)T(0.035)PNHR ; 98.973 9.46E-05 33608000 3934.65 4151.32 3765.13 4518.38 5666.16 6288.33 3437.85 1492.52 5255.99 3908.63 TRUE FALSE FALSE 3623.218301 4510.141603 3904.66903 4499.684141 5598.594743 4984.059474 3534.306819 1947.582477 4679.421047 4044.454602 0.895848429 1.115142101 0.96543772 1.112556472 1.384264454 1.232319303 0.873864876 0.481543909 1.156996804 1 11.98172945 -4.33231342 3.500988617 1.020866643 0.452735133 0.568030374 0.153323016 0.166765631 3.387344306 0.023810585 0.218819325 4.65E-05 4.33231342 -0.56813151 AEEQQLPPPLSPPS(ph)PSTPNHR ddPTM_HeLa_Curcumin_4h_R1 2 AEEQQLPPPLSPPSPSTPNHR 21 0 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9;J3KSW8;Q6WCQ1-3 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 AEEQQLPPPLS(0.044)PPS(0.862)PS(0.047)T(0.047)PNHR;AEEQQLPPPLS(0.141)PPS(0.509)PS(0.175)T(0.175)PNHR ; 158.97 5.94E-07 23668700 4636 4129 3874.5 3717.5 5629.9 6540.2 3689.5 2923.4 4426.8 3563.5 TRUE FALSE FALSE 4269.055708 4485.892362 4018.092378 3702.11797 5562.76712 5183.688797 3793.01744 3814.731202 3941.191115 3687.33136 1.15776297 1.21656882 1.089702006 1.004010112 1.508616009 1.405810406 1.028661943 1.03455069 1.068846472 1 11.84836135 AEESIEDIY(ph)ANIPDLPK ddPTM_HeLa_Curcumin_4h_R1 2 AEESIEDIYANIPDLPK 17 0 S4R313;Q9NP74-2;Q9NP74 S4R313 PALMD Palmdelphin 1 0 AEESIEDIY(1)ANIPDLPK;AEESIEDIY(1)ANIPDLPK ; 184.98 2.21E-05 5981200 2906.4 5239.5 3544.6 2525.6 2768 6412.3 2820.1 966.67 6758.5 3497 TRUE FALSE FALSE 2676.355373 5692.379033 3675.965994 2515.149736 2734.993408 5082.316698 2899.224416 1261.403233 6017.109459 3618.52049 0.739626978 1.573123339 1.015875412 0.695076826 0.755831953 1.404528926 0.801218184 0.348596405 1.662864554 1 11.82118423 -6.285977325 24.06084518 0.94666829 0.832074152 0.045244251 0.392794028 1792.941209 1758076.475 0.051715413 0.079023626 5.18E-07 6.285977325 -0.114594138 AEEYEFLTPVEEAPK ddPTM_HeLa_Curcumin_4h_R1 2 AEEYEFLTPVEEAPK 15 0 J3KTF8;J3QQX2;P52565;J3KRE2 J3KTF8 ARHGDIA Rho GDP-dissociation inhibitor 1 0 0 ; ; 200.44 7.34E-13 7813780 4007.91 2933.56 3695.39 3113.36 3356.98 4808.16 3613 3709.99 4074.19 3347.92 FALSE FALSE TRUE 3690.679694 3187.123855 3832.344404 3100.477741 3316.950206 3810.893417 3714.371056 4841.148872 3627.26155 3464.259971 1.065358756 0.920001351 1.106251966 0.894989916 0.957477278 1.100059883 1.072197551 1.39745542 1.047052352 1 11.75833148 -3.87179118 1.465310883 1.016174159 1.989003007 0.746124861 0.067364979 1.195428362 1.080055746 0.009450419 2.238596429 0.000134341 3.87179118 0.972828849 AEFEDQDDEAR ddPTM_HeLa_Curcumin_4h_R1 1 AEFEDQDDEAR 11 0 Q14692 Q14692 BMS1 Ribosome biogenesis protein BMS1 homolog 0 0 164.65 5.80E-09 0 2451.5 1756 2289.6 1964.9 1732.8 2320.1 2015.1 1658 2258 1869 FALSE FALSE TRUE 2257.461188 1907.780815 2374.45459 1956.769764 1712.137492 1838.885107 2071.638283 2163.516568 2010.303049 1933.947611 1.167281459 0.98646975 1.227776066 1.011800813 0.885307069 0.950845357 1.071196692 1.118704848 1.039481648 1 10.917333 -6.031320331 24.98466796 1.084344573 0.999831949 0.152213849 0.089942547 990.0432971 789770.5288 0.014906727 0.024738327 9.30E-07 6.031320331 -0.084512624 AEFTS(ph)PPSLFK ddPTM_HeLa_Curcumin_4h_R1 1 AEFTSPPSLFK 11 0 Q6UN15-5;Q6UN15;Q6UN15-3;A0A0B4J203;Q6UN15-4 Q6UN15-5 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 0 AEFT(0.282)S(0.703)PPS(0.015)LFK 94.402 0.014506 117410000 2947.4 2092.7 2509.4 2531.3 2446.9 3051.1 2925.4 1719.3 2949.3 2087.6 TRUE FALSE FALSE 2714.11018 2273.583663 2602.400571 2520.826151 2417.722316 2418.267467 3007.478851 2243.506655 2625.769169 2160.143945 1.25644876 1.052514889 1.204734795 1.166971376 1.119241299 1.119493668 1.392258538 1.038591276 1.215552869 1 11.07691174 -9.496787007 1.190319797 0.998091086 1.179596015 0 0.1175926 0.446518627 1.112751689 0.067609967 0.015717825 3.19E-10 9.496787007 0.181504929 AEFTVETR ddPTM_HeLa_Curcumin_4h_R1 2 AEFTVETR 8 0 P21333-2;P21333;F8WE98;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 113.7 0.0044491 7311600 4346.8 2843.8 3477.3 3644.2 4170 4614.8 3653.2 3555.8 3667.7 2893.7 FALSE FALSE TRUE 4002.746193 3089.6054 3606.171797 3629.121266 4120.275474 3657.63846 3755.69896 4639.947051 3265.362486 2994.25586 1.336808336 1.031844153 1.204363276 1.212027775 1.376059918 1.221551742 1.254301281 1.549616088 1.090542238 1 11.54798179 -13.01995661 0.202485992 6.57E-12 1.332076094 0.403352071 0.121666894 31.72073587 0.464251943 12.83582443 0.128148806 9.55E-14 13.01995661 1.332076094 AEGAAT(ph)EEEGTPK ddPTM_HeLa_Curcumin_4h_R1 3 AEGAATEEEGTPK 13 0 P80723;P80723-2;U3KQP0 P80723 BASP1 Brain acid soluble protein 1 1 0 AEGAAT(1)EEEGTPK;AEGAAT(1)EEEGTPK;AEGAAT(1)EEEGTPK ;; 180.84 0.00040307 32488700 9129.6 7479.8 8401 8707.4 9048.9 11527.1 9586.4 7078.7 9692.5 8270.5 TRUE FALSE FALSE 8406.982526 8126.320583 8712.34845 8671.371086 8940.997778 9136.249523 9855.368584 9236.963044 8629.256999 8557.899259 0.982365213 0.949569554 1.018047559 1.013259309 1.044765486 1.067580868 1.151610727 1.079349355 1.008338231 1 13.06304098 -5.424379852 1.18930779 0.989423158 1.117126995 0.783742037 0.02519925 0.151909321 0.396924801 0.003689246 0.01407158 3.76E-06 5.424379852 0.127703837 AEGAATEEEGT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 AEGAATEEEGTPK 13 0 P80723;P80723-2;U3KQP0 P80723 BASP1 Brain acid soluble protein 1 1 0 AEGAATEEEGT(1)PK;AEGAATEEEGT(1)PK;AEGAAT(0.24)EEEGT(0.76)PK ;; 187.74 6.41E-05 102530700 7698.7 6858.5 7561.1 7849.8 8233.9 10544.5 9093.6 8908.5 7716.7 6428.8 TRUE FALSE FALSE 7089.339771 7451.318179 7841.321017 7817.319608 8135.71612 8357.451839 9348.741942 11624.66064 6870.197316 6652.200321 1.065713513 1.120128351 1.178755996 1.175147956 1.223011294 1.256343982 1.405360857 1.747491067 1.03277066 1 12.6996159 -1 0.36669161 1.0257637 10.00913868 0.956898299 0.043294393 7.878920416 0.097139632 0.01278716 50.33435443 0.1 1 8.983374982 AEGAATEEEGT(ph)PKESEPQAAAEPAEAK ddPTM_HeLa_Curcumin_4h_R1 2 AEGAATEEEGTPKESEPQAAAEPAEAK 27 1 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 1 0 AEGAAT(0.014)EEEGT(0.663)PKES(0.322)EPQAAAEPAEAK;AEGAAT(0.005)EEEGT(0.75)PKES(0.244)EPQAAAEPAEAK ; 78.662 5.38E-05 132682000 6049 5492.9 6151.8 7514.9 6417 9037.1 7636.6 9502.8 9122.7 6545.6 TRUE FALSE FALSE 5570.215267 5967.6818 6379.79112 7483.805335 6340.481466 7162.703591 7850.862443 12400.15997 8121.962634 6773.059113 0.822407597 0.881091055 0.94193643 1.104937254 0.936132604 1.057528581 1.15913095 1.8308064 1.199157205 1 12.72559187 -1.345590111 0.881596359 0.923954458 200 0.824941333 0.113478485 82.25792131 0.374802408 0.013817813 32662.53171 0.045124239 1.345590111 199.0760455 S(ph)VDFHFR ddPTM_HeLa_Curcumin_4h_R1 1 SVDFHFR 7 0 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 0 S(1)VDFHFR 68.846 0.0091311 0 311.06 487.6 469.1 499.31 410.72 674.75 859.45 685.22 500.9 408.74 TRUE FALSE FALSE 286.4392728 529.7459713 486.4852587 497.2439875 405.8224322 534.799244 883.5638539 894.1404236 445.9525232 422.9436846 0.677251566 1.252521294 1.150236489 1.175674222 0.959518837 1.264469156 2.089081564 2.114088604 1.05440166 1 8.724321769 -4.856600961 2.441440043 0.930047621 2.161211697 0.844031309 0.175463505 0.086222983 1.004838584 0.031103518 0.133561217 1.39E-05 4.856600961 1.231164076 up AEGDEEGPS(ph)GASEEEDT(ph) ddPTM_HeLa_Curcumin_4h_R1 1 AEGDEEGPSGASEEEDT 17 0 Q96DX7 Q96DX7 TRIM44 Tripartite motif-containing protein 44 2 0 AEGDEEGPS(0.718)GAS(0.295)EEEDT(0.987) 104.16 0.007018 5010900 3879.8 3175.4 3424.1 3563.9 3484.2 4171.6 3146.4 3917.7 3742.6 3172.2 TRUE FALSE FALSE 3572.709736 3449.867427 3551.000158 3549.153526 3442.653191 3306.363136 3234.679516 5112.188695 3332.046144 3282.433714 1.088433171 1.051009016 1.081819305 1.081256725 1.048811184 1.007290146 0.985451588 1.557438517 1.015114526 1 11.68055016 -4.25747428 24.99989775 1.043814953 1.557438716 0.951058387 0.035210143 70.71289423 445825.9943 0.005830547 0.059428571 5.53E-05 4.25747428 0.513623762 ETNLDS(ph)LPLVDTHSK ddPTM_HeLa_Curcumin_4h_R1 4 ETNLDSLPLVDTHSK 15 0 P08670 P08670 VIM Vimentin 1 0 ET(0.002)NLDS(0.997)LPLVDT(0.001)HSK;ETNLDS(0.985)LPLVDT(0.015)HSK;ET(0.001)NLDS(0.999)LPLVDTHSK;ET(0.001)NLDS(0.995)LPLVDT(0.004)HSK ;;; 152 0.00020027 335875900 10584.2 11524.6 10035.4 11254.1 13122.6 19626.3 31236.6 26300.7 9898.9 9213.3 TRUE FALSE FALSE 9746.449402 12520.73507 10407.32075 11207.53352 12966.12157 15555.58415 32113.01493 34319.66236 8813.015436 9533.461489 1.022341089 1.313346163 1.091662327 1.1755996 1.360064398 1.631682696 3.368452787 3.599916189 0.924429752 1 13.21878442 -4.809963821 2.093193494 1.068985966 3.7072084 0.975438394 0.14729043 0.034600525 0.286046456 0.022063598 0.113612982 1.55E-05 4.809963821 2.638222434 up RDS(ph)SES(ph)QLASTESDKPTTGR ddPTM_HeLa_Curcumin_4h_R1 1 RDSSESQLASTESDKPTTGR 20 2 A0A087WVF1;Q96B23-2;Q96B23;K7EQH1 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 2 0 RDS(0.778)S(0.504)ES(0.717)QLAS(0.001)TESDKPTTGR 68.97 0.0051154 22885000 1360.5 1236.5 1132.7 1773.2 1740.4 3197.3 4989.7 4358.2 1577.3 1611.9 TRUE FALSE FALSE 1252.814989 1343.37755 1174.678858 1765.862968 1719.646867 2534.143939 5129.697553 5686.995117 1404.274136 1667.913405 0.751127118 0.805424038 0.704280483 1.058725808 1.031016875 1.519349824 3.075517912 3.409646508 0.841934678 1 10.70382867 -4.809457405 2.005739347 0.877636443 3.489812413 0.984784311 0.115970705 0.033121252 0.248504967 0.019870971 0.106227932 1.55E-05 4.809457405 2.61217597 up AEGDVAALNR ddPTM_HeLa_Curcumin_4h_R1 1 AEGDVAALNR 10 0 P67936;A0A2R8Y5V9;A0A2R8YGX3;A0A2R8YH90 P67936 TPM4 Tropomyosin alpha-4 chain 0 0 117.53 0.0033169 3350100 697.02 689.94 692.1 532.67 816.16 1041.9 484.96 876.75 708.95 633.4 FALSE FALSE TRUE 641.8501315 749.5753393 717.7498348 530.4659527 806.4278251 825.7981954 498.5666724 1144.067039 631.1799587 655.4106029 0.97930996 1.143672892 1.095114775 0.809364314 1.230416203 1.25997076 0.760693633 1.74557298 0.963029826 1 9.356255202 -4.248570216 24.90774943 1.017730268 1.745573467 0.659142959 0.154929838 869.1837076 1682240.1 0.019789059 0.486051728 5.64E-05 4.248570216 0.7278432 AEGEPQEES(ph)PLK ddPTM_HeLa_Curcumin_4h_R1 2 AEGEPQEESPLK 12 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 AEGEPQEES(1)PLK;AEGEPQEES(1)PLK ; 171.36 0.00013313 219320000 6772.4 5413.7 6420.8 6719.9 7913.9 6718.7 5750 5536.1 5485.8 5339.2 TRUE FALSE FALSE 6236.357394 5881.636105 6658.760496 6692.094834 7819.531911 5325.165885 5911.329525 7224.031405 4884.021465 5524.736803 1.128806243 1.064600236 1.205262935 1.211296587 1.415367318 0.963876846 1.069974867 1.307579286 0.884027898 1 12.43169002 -8.391196843 0.488290051 0.99389341 1.184853789 0.334323294 0.12583797 1.137456076 0.5781324 0.096307024 0.039652098 4.06E-09 8.391196843 0.190960379 AEGEPQEES(ph)PLKSK ddPTM_HeLa_Curcumin_4h_R1 2 AEGEPQEESPLKSK 14 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 AEGEPQEES(0.51)PLKS(0.49)K;AEGEPQEES(0.999)PLKS(0.001)K ; 181.51 0.00105 330809000 8428 6536.7 7013.3 6721 6194.7 8775.6 6463.8 7663.2 8268.4 7296.6 TRUE FALSE FALSE 7760.914907 7101.703221 7273.219068 6693.190283 6120.832248 6955.441639 6645.156832 9999.674403 7361.377207 7550.156307 1.027914468 0.94060347 0.96332033 0.886496916 0.810689474 0.921231476 0.880135001 1.324432766 0.974996663 1 12.8822908 -7.257200053 23.71181691 1.013181832 0.947792363 0.009745601 0.13108663 438.442414 2452337.626 0.020809157 0.024987372 5.53E-08 7.257200053 -0.065389469 AEGEPQEESPLKS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 AEGEPQEESPLKSK 14 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 AEGEPQEES(0.277)PLKS(0.723)K 77.221 0.0097508 182840000 4726.4 3775.1 4160.8 3989.8 4006.6 4647.7 4430.5 4186.3 4609.4 4509.1 TRUE FALSE FALSE 4352.300453 4101.402822 4315.002908 3973.291265 3958.823912 3683.71463 4554.807906 5462.683599 4103.760352 4665.790889 0.932810869 0.879036999 0.924817038 0.85157937 0.848478641 0.789515586 0.976213468 1.170794776 0.879542279 1 12.18790593 -8.518847901 0.872960326 0.993384918 0.913020712 0 0.103953859 0.991175375 1.552553608 0.040314372 0.021144131 3.03E-09 8.518847901 -0.080364206 AEGEWEDQEALDY(ph)FSDKESGK ddPTM_HeLa_Curcumin_4h_R1 1 AEGEWEDQEALDYFSDKESGK 21 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 AEGEWEDQEALDY(0.527)FS(0.467)DKES(0.006)GK 53.585 0.0065836 0 907.15 772.15 667.91 601.18 912.62 1001 857.74 694.82 844.77 712.46 TRUE FALSE FALSE 835.3481203 838.8912054 692.6633322 598.6924765 901.7376026 793.3813164 881.8058759 906.6674194 752.1008445 737.217932 1.133108792 1.137914813 0.939563869 0.812097008 1.223162871 1.076182879 1.196126461 1.229849926 1.020187942 1 9.525947353 AEGEWEDQEALDY(ph)FSDKESGKQK ddPTM_HeLa_Curcumin_4h_R1 1 AEGEWEDQEALDYFSDKESGKQK 23 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 AEGEWEDQEALDY(0.514)FS(0.431)DKES(0.056)GKQK 51.688 0.0083729 78139000 4710.3 3179.2 3280.9 3584.8 2359.5 4913.6 3123.7 3050 6293.3 4770.3 TRUE FALSE FALSE 4337.474785 3453.995882 3402.49304 3569.967047 2331.364504 3894.463972 3211.342615 3979.93096 5602.940735 4936.06757 0.878730836 0.699746475 0.689312493 0.723241122 0.472312113 0.78898109 0.650587248 0.806295883 1.135102114 1 12.26914643 -7.47730365 1.162720888 0.965210063 0.677207615 0.655496097 0.104027872 0.178650697 0.482016164 0.018764828 0.020166318 3.33E-08 7.47730365 -0.288002448 AEGEWEDQEALDYFS(ph)DK ddPTM_HeLa_Curcumin_4h_R1 1 AEGEWEDQEALDYFSDK 17 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 AEGEWEDQEALDY(0.001)FS(0.999)DK 118.05 0.00072603 6370300 1078.6 1219 1291 1424.9 1570.4 1513.5 1229.2 1421.7 1528 1267.5 TRUE FALSE FALSE 993.2276719 1324.364928 1338.845596 1419.004141 1551.674006 1199.583039 1263.688044 1855.169785 1360.382223 1311.545531 0.757295609 1.009774268 1.020815187 1.08193281 1.183088173 0.914633165 0.963510617 1.414491333 1.037235987 1 10.35705218 -6.875266472 2.522207702 0.88585969 1.089549245 0.175800416 0.148296066 0.280998303 3.643634054 0.025362949 0.034464898 1.33E-07 6.875266472 0.203689555 AEGEWEDQEALDYFS(ph)DKESGK ddPTM_HeLa_Curcumin_4h_R1 7 AEGEWEDQEALDYFSDKESGK 21 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 AEGEWEDQEALDY(0.035)FS(0.915)DKES(0.05)GK;AEGEWEDQEALDY(0.048)FS(0.643)DKES(0.309)GK;AEGEWEDQEALDY(0.107)FS(0.84)DKES(0.053)GK;AEGEWEDQEALDY(0.015)FS(0.977)DKES(0.008)GK;AEGEWEDQEALDY(0.017)FS(0.932)DKES(0.051)GK;AEGEWEDQEALDY(0.076)FS(0.822)DKES(0.102)GK;AEGEWEDQEALDY(0.171)FS(0.804)DKES(0.025)GK ;;;;;; 120.85 6.10E-06 2318727000 23489 19672.7 20409.9 21900 22756.7 24250.6 23294.56 21422.6 20979.9 20377.1 TRUE FALSE FALSE 21629.82086 21373.12053 21166.30885 21809.3836 22485.34122 19220.7522 23948.14266 27954.25212 18678.45746 21085.20271 1.025829401 1.01365497 1.00384659 1.034345456 1.066403844 0.911575405 1.135779579 1.32577583 0.885856196 1 14.36394327 -4.415869131 3.246633845 1.012009595 1.328243275 0.768104153 0.056081053 0.063732587 1.109488955 0.0049625 0.039966154 3.84E-05 4.415869131 0.31623368 AEGEWEDQEALDYFS(ph)DKESGKQK ddPTM_HeLa_Curcumin_4h_R1 1 AEGEWEDQEALDYFSDKESGKQK 23 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 AEGEWEDQEALDY(0.218)FS(0.595)DKES(0.187)GKQK 45.659 0.012423 23078000 5532 3515.2 3523.6 4531.3 2826.6 5121.7 3855.1 4035.6 6596.4 6011.9 TRUE FALSE FALSE 5094.136363 3819.038225 3654.187716 4512.550681 2792.894641 4059.401687 3963.263731 5266.035862 5872.791423 6220.813078 0.81888594 0.613913033 0.5874132 0.72539564 0.448959743 0.652551626 0.637097383 0.846518903 0.944055279 1 12.60288744 -7.783573336 0.965033626 0.960402636 0.6349265 0.614612114 0.101548028 0.208021137 0.409749833 0.026480427 0.023667716 1.65E-08 7.783573336 -0.325476136 AEGFVDALHR ddPTM_HeLa_Curcumin_4h_R1 2 AEGFVDALHR 10 0 Q96I24;A0A494C1K6 Q96I24 FUBP3 Far upstream element-binding protein 3 0 0 ; ; 128.51 0.0024985 7827000 11670.5 9440.8 10864.4 9884.3 10062.1 16750.6 12122.1 10372 12540.2 11446.4 FALSE FALSE TRUE 10746.76761 10256.82068 11267.04422 9843.401386 9942.116029 13276.33674 12462.2135 13534.37505 11164.57143 11844.16155 0.907347267 0.865981154 0.951274109 0.831076252 0.839410708 1.120918242 1.052181993 1.142704361 0.942622354 1 13.53188845 -5.245656535 24.85126767 0.931611711 1.099959597 0.703862299 0.057652778 432.3320396 680737.7379 0.009680714 0.024589348 5.68E-06 5.245656535 0.168347886 AEGPDVAVDLPK ddPTM_HeLa_Curcumin_4h_R1 2 AEGPDVAVDLPK 12 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 120.63 0.0010471 3087600 2765.1 2402.35 2760.8 3005.9 3404.5 3604.7 2641.5 2784.5 2644.7 2176.01 FALSE FALSE TRUE 2546.239417 2609.998429 2863.117677 2993.462382 3363.903561 2857.044587 2715.613381 3633.481232 2354.583027 2251.626186 1.130844646 1.159161519 1.271577713 1.329466854 1.49398847 1.268880512 1.206067596 1.613714237 1.045725548 1 11.13675162 -6.945972047 0.498950853 1.014921609 1.41315022 0.645543579 0.107746696 0.389484684 0.220287273 0.03724233 0.057823133 1.13E-07 6.945972047 0.398228611 AEGPEVDVNLPK ddPTM_HeLa_Curcumin_4h_R1 2 AEGPEVDVNLPK 12 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 183.85 1.28E-09 19304300 7685.4 6143.6 6770.5 7409.1 6285.9 7949.8 6263.4 6310.9 7364.1 5857.2 FALSE FALSE TRUE 7077.09248 6674.625409 7021.420686 7378.443107 6210.944748 6300.921867 6439.134147 8235.064358 6556.276654 6060.737264 1.16769498 1.101289351 1.158509333 1.217416757 1.024783698 1.039629602 1.062434134 1.358756204 1.081762229 1 12.56527759 -9.358312276 0.966024338 0.996040258 1.135637322 0.126278359 0.095913057 0.707195576 1.126843543 0.071386754 0.016590008 4.38E-10 9.358312276 0.139597064 AEGPGLSK ddPTM_HeLa_Curcumin_4h_R1 2 AEGPGLSK 8 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 94.302 0.018628 7378500 7184 7078.9 8490.8 6528.5 8087.3 9659.6 7417.5 6692.4 7449.7 7132.7 FALSE FALSE TRUE 6615.378819 7690.768573 8805.476517 6501.486797 7990.864229 7656.090074 7625.615087 8732.881952 6632.486548 7380.560794 0.896324684 1.042030381 1.193063341 0.880893333 1.082690659 1.037331754 1.033202666 1.183227426 0.898642628 1 12.84951472 -7.125225503 6.542997618 0.951267299 1.062173966 0.32674739 0.086460117 0.242974132 12.03386777 0.014077157 0.017287153 7.50E-08 7.125225503 0.110906667 AEGPGLSR ddPTM_HeLa_Curcumin_4h_R1 2 AEGPGLSR 8 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 143.89 0.00047017 19104900 6981.7 6386.7 7296.1 6985.9 7230.8 7854.5 6821.6 6786.4 7339.6 6669.8 FALSE FALSE TRUE 6429.091078 6938.737889 7566.499884 6956.994197 7144.577433 6225.388162 7012.995737 8855.542119 6534.464243 6901.575054 0.931539689 1.005384689 1.096343925 1.008029927 1.035209699 0.902024264 1.01614424 1.283119006 0.946807677 1 12.75270993 -6.999008585 24.65751596 0.967713132 1.045239585 0.177245632 0.09210244 44.22446704 1099849.437 0.01475893 0.019305434 1.00E-07 6.999008585 0.077526453 AEGSSTAS(ph)SGSQLAEGK ddPTM_HeLa_Curcumin_4h_R1 1 AEGSSTASSGSQLAEGK 17 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;A0A0C4DH52;Q9NZB2-2;Q9NZB2-5 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 0 AEGSST(0.001)AS(0.655)S(0.114)GS(0.23)QLAEGK 259.34 6.03E-41 16869000 1939.8 1817.8 1758.1 1906.8 2029.6 2040.9 1627.3 1056.9 1949.6 1656.6 TRUE FALSE FALSE 1786.262783 1974.922532 1823.256733 1898.910167 2005.398346 1617.594334 1672.957658 1379.143945 1735.733758 1714.166727 1.042058952 1.152118112 1.063640254 1.107774487 1.169896903 0.943662194 0.975959708 0.804556478 1.012581641 1 10.74329172 -4.260899307 1.442106345 1.047289985 0.712828699 0.600879082 0.064469159 0.747831621 1.369980699 0.010260213 0.35940474 5.48E-05 4.260899307 -0.334461286 AEGSSTASSGS(ph)QLAEGK ddPTM_HeLa_Curcumin_4h_R1 1 AEGSSTASSGSQLAEGK 17 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;A0A0C4DH52;Q9NZB2-2;Q9NZB2-5 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 0 AEGSSTAS(0.027)S(0.117)GS(0.857)QLAEGK 241.8 1.90E-30 7387100 2782 2083.4 2033 2652.7 2198.9 2592.9 2240.5 2722.4 2502.5 2030.5 TRUE FALSE FALSE 2561.801764 2263.479813 2108.344768 2641.72383 2172.679554 2055.103312 2303.3624 3552.447228 2227.982011 2101.059724 1.219290311 1.077303889 1.003467319 1.257329242 1.034087479 0.978127032 1.096286019 1.690788314 1.0604087 1 11.03690146 -4.261526482 9.618355646 1.093894378 1.692609039 0.810801317 0.088206637 0.028231712 70.84342609 0.014154673 0.109819059 5.48E-05 4.261526482 0.598714661 AEGVS(ph)TPLAGR ddPTM_HeLa_Curcumin_4h_R1 1 AEGVSTPLAGR 11 0 P29590;P29590-11 P29590 PML Protein PML 1 0 AEGVS(0.5)T(0.5)PLAGR 108.31 0.0073361 25103000 5384.6 4744.3 4599.9 4558.2 4858.8 5806.2 5558.7 3235.3 4974.5 4781.2 TRUE FALSE FALSE 4958.403228 5154.376152 4770.37634 4539.339376 4800.861983 4601.928671 5714.662162 4221.728077 4428.809796 4947.346344 1.002234912 1.041846637 0.964229308 0.917530138 0.970391327 0.930181223 1.155096442 0.853331823 0.895188953 1 12.27243919 -6.702659817 24.99547357 1.004144501 0.970249025 0 0.080977013 195.0429468 82939.18031 0.010566786 0.014943686 1.98E-07 6.702659817 -0.033895475 AEGYEVAHGGR ddPTM_HeLa_Curcumin_4h_R1 1 AEGYEVAHGGR 11 0 A8MU39;H0YDU8;P53041 A8MU39 PPP5C Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase 5 0 0 105.17 0.0017551 697520 320.67 298.71 208.32 464.25 387.71 135.59 300.26 308.14 296.04 413.03 FALSE FALSE TRUE 295.2886311 324.5291614 216.0405225 462.3290565 383.0868115 107.4671056 308.6844875 402.0904675 263.5651527 427.3827618 0.69092312 0.759340784 0.505496575 1.081768143 0.896355318 0.251454001 0.722267052 0.940820509 0.616695796 1 8.739384909 -9.264836601 0.811643225 1.015271876 0.722886242 0 0.248674029 1.011557717 1.098282699 0.191728395 0.042851536 5.43E-10 9.264836601 -0.292385634 AEHLES(ph)PQLGGK ddPTM_HeLa_Curcumin_4h_R1 1 AEHLESPQLGGK 12 0 Q9NYD6;D6RAG4 Q9NYD6 HOXC10 Homeobox protein Hox-C10 1 0 AEHLES(1)PQLGGK 84.759 0.0095133 29229000 7173.9 5589.8 6090.6 6989.9 6614.6 8048.2 7399 9939.6 8034.8 6515.6 TRUE FALSE FALSE 6606.078245 6072.957404 6316.322994 6960.977646 6535.725215 6378.912598 7606.596027 12970.13828 7153.402542 6742.016615 0.979837135 0.900762747 0.936859601 1.032477083 0.969402122 0.946143114 1.128237508 1.923777265 1.061018231 1 12.71896447 -4.258079091 2.988462532 0.979584884 2.083807993 0.9759357 0.044299111 0.034337767 0.440874189 0.00534219 0.090506105 5.52E-05 4.258079091 1.104223109 AEHMETNAVGPS(ph)PSSDTR ddPTM_HeLa_Curcumin_4h_R1 4 AEHMETNAVGPSPSSDTR 18 0 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9;J3KSW8;Q6WCQ1-3 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 AEHMETNAVGPS(0.442)PS(0.234)S(0.234)DT(0.089)R;AEHMETNAVGPS(0.632)PS(0.154)S(0.154)DT(0.059)R;AEHMETNAVGPS(0.995)PS(0.005)SDTR;AEHMETNAVGPS(1)PSSDTR ;;; 245.1 3.64E-32 111509000 6871.9 5840.59 6756.47 6282.2 6797.2 8182.4 5339.63 2297.75 6978.1 5552.12 TRUE FALSE FALSE 6327.981864 6345.424574 7006.870722 6256.205921 6716.147829 6485.278005 5489.445647 2998.323397 6212.619888 5745.055757 1.101465701 1.104501826 1.219634938 1.088972185 1.169030922 1.128845094 0.95550781 0.52189631 1.081385482 1 12.48810518 -4.28646611 2.809739584 1.080785662 0.436515508 0.890851914 0.06144884 0.115325228 1.289953552 0.010708761 0.165005601 5.17E-05 4.28646611 -0.644270153 AEIIADK(ac)QSGK ddPTM_HeLa_Curcumin_4h_R1 1 AEIIADKQSGK 11 1 Q13151 Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0 0 1 AEIIADK(1)QSGK 169.52 7.66E-09 2467100 1986 1635.7 1478.4 1488.5 1990.8 2590.4 2025.1 2446.8 2552.7 1618.8 FALSE TRUE FALSE 1828.806004 1777.082619 1533.190805 1482.340981 1967.06101 2053.12184 2081.918856 3192.818056 2272.675197 1675.05318 1.091789817 1.060911165 0.915308734 0.884951594 1.174327499 1.225705467 1.24289717 1.906099517 1.356777937 1 10.70999118 -1.227118684 0.850094714 1.030494565 199.9995824 0.76993032 0.133589176 92.61015002 0.377239161 0.014157771 35461.30322 0.059276331 1.227118684 198.9690879 AEIKEMLAS(ph)DDEEDVSSKVEK ddPTM_HeLa_Curcumin_4h_R1 2 AEIKEMLASDDEEDVSSKVEK 21 2 E7ETM8;Q0ZGT2-4 E7ETM8 NEXN Nexilin 1 0 AEIKEMLAS(0.99)DDEEDVS(0.005)S(0.005)KVEK;AEIKEMLAS(1)DDEEDVSSKVEK ; 106.7 4.25E-05 112644000 2781.2 1934.46 1921.83 2318.4 1406.75 2392.6 1743.01 2445.5 3107.5 2259.3 TRUE FALSE FALSE 2561.065085 2101.666103 1993.05471 2308.807075 1389.975425 1896.34779 1791.91417 3191.121692 2766.615025 2337.810507 1.095497295 0.898989074 0.852530479 0.987593763 0.594562913 0.811164029 0.766492478 1.365004427 1.183421418 1 11.19094228 -7.179097744 5.840637426 1.044946597 0.877277715 0.161820371 0.192668896 0.323159485 18.14493708 0.029951908 0.036737216 6.62E-08 7.179097744 -0.167668883 AEIS(ph)FEDR ddPTM_HeLa_Curcumin_4h_R1 2 AEISFEDR 8 0 P21333-2;P21333;H0Y5C6;Q60FE5 P21333-2;Q60FE5 FLNA Filamin-A 1 0 AEIS(1)FEDR;AEIS(1)FEDR ; 101.66 0.014078 17028900 5547.4 4782.6 5392.7 5101.1 6292.2 6379.1 5080.4 4449.6 5227.3 4343.4 TRUE FALSE FALSE 5108.317436 5195.986633 5592.558206 5079.993 6217.169625 5056.002753 5222.942351 5806.262557 4653.878268 4494.332827 1.136613071 1.156119681 1.244357822 1.130310815 1.383335384 1.124972927 1.162117394 1.29190756 1.035499249 1 12.13389125 -8.201822559 0.43878482 0.987681117 1.230683145 0.529221428 0.074452318 0.572231672 0.255203132 0.058674537 0.028219074 6.28E-09 8.201822559 0.243002028 AEISFEDR ddPTM_HeLa_Curcumin_4h_R1 1 AEISFEDR 8 0 P21333-2;P21333;H0Y5C6;Q60FE5 P21333-2;Q60FE5 FLNA Filamin-A 0 0 147.52 0.018875 8657000 1887.9 1381.4 1565.1 1753.7 2027.2 2171.5 1980.6 1546.4 1622 1308 FALSE FALSE TRUE 1738.470723 1500.802061 1623.103983 1746.443654 2003.026964 1721.106422 2036.170305 2017.890241 1444.070658 1353.452903 1.284470793 1.108869069 1.199231964 1.290361601 1.47993843 1.271641162 1.50442642 1.490920177 1.066953017 1 10.40242897 -1 0.052785762 0.411607691 2.997750924 0.753751974 0.085022781 150.593119 0.604659533 6.799358379 31.32780024 0.1 1 2.586143234 AEISFEDRK ddPTM_HeLa_Curcumin_4h_R1 4 AEISFEDRK 9 1 P21333-2;P21333;H0Y5C6;Q60FE5 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ;;; ;;; 117.81 0.0099669 227180000 17609.2 14083 16167 15923.4 16275 19072.3 16053.5 14268.4 16483.1 14607.4 FALSE FALSE TRUE 16215.41324 15300.27177 16766.16324 15857.51319 16080.93125 15116.48999 16503.918 18618.76948 14674.94517 15115.00606 1.072802298 1.012257071 1.109239598 1.049123839 1.063905048 1.000098176 1.091889605 1.231806947 0.970885827 1 13.88369394 -4.320216792 2.989847565 1.040176389 1.251080991 0.693389149 0.039413791 0.132735251 1.81441832 0.005155266 0.061569727 4.78E-05 4.320216792 0.210904602 AEITFDDHK ddPTM_HeLa_Curcumin_4h_R1 6 AEITFDDHK 9 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3 O75369-8 FLNB Filamin-B 0 0 ;;;;; ;;;;; 163.16 0.00038339 66350500 31145.9 28515 30109.8 28930.7 33190.6 35444.3 29265.7 27546.3 28744.1 25706.4 FALSE FALSE TRUE 28680.66915 30979.70954 31225.69568 28810.99243 32794.82377 28092.75264 30086.81678 35945.04006 25590.94414 26599.69549 1.078232988 1.164664067 1.173911772 1.083132416 1.232902226 1.056130611 1.131096286 1.351332765 0.962076583 1 14.69912211 -1 0.062375369 0.768807817 1.906989375 0.543704212 0.073283442 172.2138277 0.808623552 2.944338865 17.74227389 0.1 1 1.138181558 AELGMGDST(ph)SQSPPIKR ddPTM_HeLa_Curcumin_4h_R1 1 AELGMGDSTSQSPPIKR 17 1 Q9NR19;Q9NR19-2 Q9NR19 ACSS2 "Acetyl-coenzyme A synthetase, cytoplasmic" 1 0 AELGMGDS(0.185)T(0.379)S(0.379)QS(0.058)PPIKR 91.701 0.0019737 9207100 3698.4 2372 3217.4 3598.5 2804.9 3542.8 2998.6 2377.2 3581.8 2931.4 TRUE FALSE FALSE 3405.667737 2577.025111 3336.639674 3583.61036 2771.453399 2807.983344 3082.732646 3101.997337 3188.885501 3033.265932 1.122772554 0.849587596 1.100015544 1.181436261 0.913686258 0.925729365 1.01630807 1.022659208 1.051304295 1 11.56665627 -5.715838541 24.99977551 1.053180217 0.969799082 0.168895725 0.08821342 188.890992 103554.8346 0.013441497 0.026882919 1.92E-06 5.715838541 -0.083381135 AELGMGDSTS(ph)QSPPIKR ddPTM_HeLa_Curcumin_4h_R1 1 AELGMGDSTSQSPPIKR 17 1 Q9NR19;Q9NR19-2 Q9NR19 ACSS2 "Acetyl-coenzyme A synthetase, cytoplasmic" 1 0 AELGMGDS(0.058)T(0.238)S(0.703)QSPPIKR 68.952 0.013154 32116000 3588.6 3159.7 3453.4 3774 3299.2 3846.4 2953 2705.5 3962.8 3578.3 TRUE FALSE FALSE 3304.558523 3432.810389 3581.386042 3758.384188 3259.859195 3048.613282 3035.853232 3530.394495 3528.090754 3702.645659 0.89248576 0.927123658 0.967250548 1.015053703 0.880413492 0.823360797 0.8199146 0.953478896 0.952856708 1 11.85434078 -5.584054997 8.808844068 0.951759178 0.859499598 0.460145018 0.047331311 0.232381383 30.82870553 0.008041064 0.016113169 2.61E-06 5.584054997 -0.09225958 AELNEFLTR ddPTM_HeLa_Curcumin_4h_R1 2 AELNEFLTR 9 0 E9PL09;P23396;P23396-2;E9PPU1;E9PQ96;E9PJH4;F2Z2S8;E9PK82;H0YCJ7;H0YEU2;H0YF32;E9PQX2;H0YES8 E9PL09 RPS3 40S ribosomal protein S3 0 0 ; ; 109.44 0.0038047 12553700 5034.5 4006.7 4783.3 4278.9 4629.2 5858 4918.8 4951.6 4902.5 3953.9 FALSE FALSE TRUE 4636.014013 4353.021294 4960.573306 4261.195046 4573.999813 4642.984767 5056.80829 6461.320046 4364.708015 4091.297731 1.13314022 1.063970794 1.2124694 1.04152651 1.117982634 1.134844021 1.235991273 1.579283756 1.066827277 1 11.99834281 -1.000008416 0.822484308 1.073486502 150.7393557 0.876296279 0.055048296 149.5146512 0.444987927 0.010340116 41803.54819 0.099998062 1.000008416 149.6658692 DGGAAS(ph)PATEGR ddPTM_HeLa_Curcumin_4h_R1 1 DGGAASPATEGR 12 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 0 DGGAAS(1)PATEGR 142.39 0.0010542 110080000 2131.6 1748.8 2323.7 1442.3 1486.9 1009.8 774.07 384.29 2443.1 2082.4 TRUE FALSE FALSE 1962.881611 1899.958479 2409.818366 1436.332145 1469.169689 800.3560972 795.7883209 501.4582519 2175.098042 2154.763245 0.910950015 0.881748138 1.118368049 0.666584669 0.681824183 0.371435748 0.369315897 0.232720812 1.009437138 1 11.07331365 -5.513374343 1.089096542 0.961919198 0.265084069 0.904916958 0.090927914 0.108645577 0.238898406 0.013809226 0.05159847 3.07E-06 5.513374343 -0.69683513 down AELSEGQVR ddPTM_HeLa_Curcumin_4h_R1 2 AELSEGQVR 9 0 P09493-3;H0YKX5;H7BYY1;P09493-2;P09493-8;F5H7S3;B7Z596;H0YL42;P09493-4;P09493-10 P09493-3;P09493-4 TPM1 Tropomyosin alpha-1 chain 0 0 ; ; 152.34 5.81E-07 11502200 5974.3 5253.2 6076 5671.2 5580.1 7072.7 5971.5 5568.8 5968.7 4774.9 FALSE FALSE TRUE 5501.427851 5707.2632 6301.181905 5647.734077 5513.560952 5605.742294 6139.044219 7266.701484 5313.948543 4940.82742 1.113462864 1.155122961 1.275329286 1.14307455 1.115918546 1.134575612 1.242513388 1.470745862 1.075517943 1 12.27053695 -1 0.152524116 0.977548886 2.319608968 0.578687543 0.080256222 34.77867417 0.341116696 0.172982974 10.41246637 0.1 1 1.342060082 AEMELSDLIRK ddPTM_HeLa_Curcumin_4h_R1 1 AEMELSDLIRK 11 1 B4DFN3;Q13563-5;Q13563-3;Q13563 B4DFN3 PKD2 Polycystin-2 0 0 99.136 0.017748 4576700 1522.8 1400.8 1071.6 881.34 1618.2 2465.8 1401 1122.4 1622.5 1182.7 FALSE FALSE TRUE 1402.268773 1521.87891 1111.314439 877.6932486 1598.904022 1954.365285 1440.308289 1464.614593 1444.515809 1223.798737 1.145832832 1.243569604 0.90808595 0.717187575 1.306508966 1.596966254 1.17691598 1.196777337 1.180354061 1 10.2571506 -5.562640364 24.99995648 1.04813736 1.332698128 0.387790508 0.175857604 122.0668398 76748.68875 0.025703684 0.051407425 2.74E-06 5.562640364 0.284560768 AENGERS(ph)DLEEDNER ddPTM_HeLa_Curcumin_4h_R1 2 AENGERSDLEEDNER 15 1 Q8WU90 Q8WU90 ZC3H15 Zinc finger CCCH domain-containing protein 15 1 0 AENGERS(1)DLEEDNER;AENGERS(1)DLEEDNER ; 111.81 0.00089141 28580000 4130 3468.8 3851.5 3335.4 4209.3 3952.8 3315.4 2103.5 3087.6 3176.2 TRUE FALSE FALSE 3803.106142 3768.627615 3994.239978 3321.598999 4159.106847 3132.944723 3408.421201 2744.847467 2748.898005 3286.572714 1.157164765 1.146674041 1.215320739 1.010657389 1.265484506 0.953255867 1.037074636 0.835170162 0.836402613 1 11.68236819 -4.049234784 1.203604737 1.095924239 0.621242252 0.250296452 0.122377268 1.860693544 1.602053807 0.014420324 1.239094377 8.93E-05 4.049234784 -0.474681988 QVLQSTQS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 QVLQSTQSPR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 QVLQS(0.003)T(0.002)QS(0.995)PR;QVLQS(0.015)T(0.008)QS(0.977)PR ; 111.72 0.0068673 176637000 5104.8 4421.9 4655.2 4619.1 5159.9 7052.7 8330.1 7046.2 5126.8 4226.8 TRUE FALSE FALSE 4700.749693 4804.109332 4827.725807 4599.987388 5098.371563 5589.89052 8563.820187 9194.553943 4564.402867 4373.680985 1.074781108 1.098413293 1.103812972 1.051742778 1.165693515 1.278074587 1.95803494 2.102246134 1.04360672 1 12.09463228 -4.788107447 2.002581552 1.053054357 2.141365059 0.983723133 0.048427293 0.033169892 0.246238938 0.00810855 0.044982092 1.63E-05 4.788107447 1.088310702 up AENGTGSS(ph)PRGPGCSLR ddPTM_HeLa_Curcumin_4h_R1 2 AENGTGSSPRGPGCSLR 17 1 M0R102;Q9NQT4;M0R050 M0R102 EXOSC5 Exosome complex component RRP46 1 0 AENGT(0.008)GS(0.253)S(0.693)PRGPGCS(0.046)LR;AENGT(0.021)GS(0.217)S(0.711)PRGPGCS(0.051)LR ; 60.158 0.015151 35671000 1839.18 1434.93 1107.2 1761.29 902.3 1963.98 1240.76 1423.36 2318.88 2180.32 TRUE FALSE FALSE 1693.606962 1558.958955 1148.233806 1754.002249 891.5406618 1556.628409 1275.572386 1857.335912 2064.504666 2256.085958 0.750683704 0.691001577 0.508949494 0.777453644 0.395171407 0.689968573 0.565391749 0.823255827 0.91508245 1 11.13960632 -8.2809478 0.596603792 0.99267148 0.618230424 0.514410546 0.121972158 0.363629843 0.283576316 0.060822268 0.030822372 5.24E-09 8.2809478 -0.374441057 AENMYAQIK ddPTM_HeLa_Curcumin_4h_R1 1 AENMYAQIK 9 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 0 0 96.492 0.013532 3040500 1930.9 1731.9 1695.5 1991.7 2146.3 292.14 578.36 661.69 1830.9 1729.2 FALSE FALSE TRUE 1778.067228 1881.597719 1758.336722 1983.458873 2120.706774 231.5468709 594.587225 863.436235 1630.054851 1789.289571 0.993728045 1.051589273 0.982701039 1.10851754 1.185222788 0.129407154 0.332303521 0.482558133 0.911006735 1 10.80517117 -5.26249641 24.99999998 1.019500093 0.316510977 0.905184542 0.106497094 18.20256821 430518.7059 0.01414885 0.033404776 5.46E-06 5.26249641 -0.702989116 AENNS(ph)EVGASGYGVPGPTWDR ddPTM_HeLa_Curcumin_4h_R1 2 AENNSEVGASGYGVPGPTWDR 21 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 1 0 AENNS(0.998)EVGAS(0.002)GYGVPGPTWDR;AENNS(0.996)EVGAS(0.001)GY(0.001)GVPGPT(0.001)WDR ; 174.26 5.43E-09 26667000 1880.74 1698.79 1922.15 2183.34 1727.43 2423.91 2143.91 1498.12 2252.97 2000.33 TRUE FALSE FALSE 1731.877444 1845.625838 1993.38657 2174.305918 1706.831525 1921.163743 2204.062345 1954.889892 2005.824828 2069.841319 0.836719911 0.891675039 0.963062507 1.050469859 0.824619506 0.928169578 1.064846046 0.944463652 0.969071788 1 11.01530445 -6.734349158 22.2967169 0.918399597 0.963409101 0.057282935 0.074393903 163.0218543 134173.7057 0.013658602 0.019310677 1.84E-07 6.734349158 0.045009503 AENNSEVGASGYGVPGPTWDR ddPTM_HeLa_Curcumin_4h_R1 1 AENNSEVGASGYGVPGPTWDR 21 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 0 225.17 1.96E-24 5691700 695.66 733.64 709.77 718.52 559.35 791.64 691.01 525.19 783.61 710.84 FALSE FALSE TRUE 640.5977769 797.0525726 736.0747006 715.5469546 552.6801166 627.4449404 710.3978808 685.3180133 697.6499435 735.5416371 0.870919802 1.083626721 1.000724722 0.972816383 0.75139202 0.853037964 0.965815999 0.931718857 0.948484638 1 9.522663201 AENSAALGKPTAGTTDAGEAAK(ac)ILAEK ddPTM_HeLa_Curcumin_4h_R1 1 AENSAALGKPTAGTTDAGEAAKILAEK 27 2 Q96T17;Q96T17-2;Q96T17-5;Q96T17-4 Q96T17 MAP7D2 MAP7 domain-containing protein 2 0 1 AENSAALGKPTAGTTDAGEAAK(1)ILAEK 205.24 1.06E-25 5275800 994.14 920.81 1160.9 731.33 1214.3 1206.4 1119.2 1236.7 1079.9 906.62 FALSE TRUE FALSE 915.45277 1000.400713 1203.923975 728.3039502 1199.820266 956.1790411 1150.60174 1613.764137 961.4376718 938.1249775 0.975832423 1.066383198 1.283330051 0.776340006 1.278955677 1.019244838 1.226490891 1.720201653 1.024850308 1 9.873636322 -1.121677964 0.850099571 1.011224451 200 0.661786286 0.141970882 199.4033927 0.663342114 0.02028385 76570.9829 0.075565235 1.121677964 198.9887755 AENYDIPSADR ddPTM_HeLa_Curcumin_4h_R1 4 AENYDIPSADR 11 0 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 0 ;;; ;;; 190.26 0.00034506 119695000 17057.6 15147.7 17438.3 15826.3 22345.4 29549.4 19029.2 17134.3 26812 15783.4 FALSE FALSE TRUE 15707.47296 16456.99969 18084.57874 15760.81496 22078.9457 23420.52135 19563.10814 22358.46919 23870.79068 16331.87198 0.961768068 1.007661566 1.107318179 0.965034197 1.351893141 1.434037775 1.197848487 1.369008355 1.461607752 1 13.99540254 -5.760306122 24.99999554 0.993059297 1.335017876 0.285290398 0.162689654 7.714634274 170179.4169 0.0096603 0.018486131 1.74E-06 5.760306122 0.34195858 AEPAK(ac)IEAFR ddPTM_HeLa_Curcumin_4h_R1 2 AEPAKIEAFR 10 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 1 ; AEPAK(1)IEAFR;AEPAK(1)IEAFR 120.06 0.0028813 15165500 3212 2893.7 2577.1 3172.3 3474.9 6037 4557.7 5035.2 6384.8 3494 FALSE TRUE FALSE 2957.766811 3143.818534 2672.609593 3159.173863 3433.464087 4784.858149 4685.576796 6570.409301 5684.403414 3615.41624 0.818098558 0.869559222 0.739225974 0.873806404 0.949673249 1.323459826 1.295999267 1.817331357 1.572268042 1 11.81994604 -4.380179941 0.91655833 0.889877493 2.153078044 0.516802195 0.237333026 0.454262969 0.321211107 0.017811753 0.546238851 4.17E-05 4.380179941 1.263200551 AEPAKIEAFR ddPTM_HeLa_Curcumin_4h_R1 1 AEPAKIEAFR 10 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 0 91.265 0.015845 26921000 2273.8 1648.3 1994.1 1815.3 1286.7 2374.4 1704.1 1732.1 2598.1 2214 FALSE FALSE TRUE 2093.826331 1790.771707 2068.0031 1807.78877 1271.356943 1881.922675 1751.91246 2260.209316 2313.09493 2290.936335 0.913960942 0.781676767 0.902689031 0.789104761 0.554950796 0.821464414 0.764714598 0.986587572 1.009672288 1 11.16172165 -7.487320233 0.844804371 0.980733726 0.781882576 0.371852 0.105435563 0.402215969 0.595889044 0.026734948 0.027854361 3.26E-08 7.487320233 -0.19885115 AEPASPDS(ph)PKGSSETETEPPVALAPGPAPTR ddPTM_HeLa_Curcumin_4h_R1 1 AEPASPDSPKGSSETETEPPVALAPGPAPTR 31 1 F5GWT5;A0A6E1WCP9;P11474-2;P11474 F5GWT5 ESRRA Steroid hormone receptor ERR1 1 0 AEPAS(0.033)PDS(0.785)PKGS(0.144)S(0.033)ET(0.002)ET(0.003)EPPVALAPGPAPTR 59.598 0.00064318 8764700 1090.5 1239.9 1218.4 1316 1106.8 1120.7 885.62 960.14 1235.4 1232.2 TRUE FALSE FALSE 1004.185774 1347.071431 1263.554976 1310.554741 1093.602133 888.2541871 910.4681137 1252.882266 1099.879711 1275.018858 0.787585037 1.056510986 0.991008853 1.027870868 0.857714477 0.696659647 0.714082076 0.982638224 0.862637994 1 10.31630287 -5.522547115 24.99999992 0.926716163 0.787382995 0.290939356 0.105723639 13.6359844 1027930.702 0.017471001 0.035257239 3.00E-06 5.522547115 -0.139333168 AEPDESNAR ddPTM_HeLa_Curcumin_4h_R1 1 AEPDESNAR 9 0 P61088;Q5JXB2;F8VZ29;F8VSD4;F8VV71 P61088 UBE2N;UBE2NL Ubiquitin-conjugating enzyme E2 N;Putative ubiquitin-conjugating enzyme E2 N-like 0 0 137.13 0.00021061 531710 399.01 766.83 458.56 546.88 382.91 407.44 387 413.47 456.41 463.04 FALSE FALSE TRUE 367.4279375 833.1113683 475.554637 544.6171555 378.3440483 322.9323512 397.8581784 539.5350996 406.3429649 479.1306055 0.766863843 1.738798062 0.992536547 1.136677869 0.789647006 0.6739965 0.830375213 1.126071041 0.848083926 1 8.904275162 -4.231918777 21.39275008 0.943688325 1.126073039 0.013790587 0.28717782 4630.201171 3354982.772 0.040056134 4.031274297 5.86E-05 4.231918777 0.182384714 AEPEAGEEQAGDDRDSGGPVLQFDYEAVANR ddPTM_HeLa_Curcumin_4h_R1 1 AEPEAGEEQAGDDRDSGGPVLQFDYEAVANR 31 1 P56182 P56182 RRP1 Ribosomal RNA processing protein 1 homolog A 0 0 53.722 0.002688 6063500 1028.2 839.73 1140.9 1065.3 1019.6 1132.2 940.62 636.66 1259.5 1049 FALSE FALSE TRUE 946.816885 912.3125194 1183.182758 1060.892071 1007.441936 897.3689575 967.0112657 830.7747032 1121.336001 1085.452672 0.872278368 0.840490371 1.090036248 0.977372942 0.928130689 0.826723247 0.890882938 0.765371651 1.033058401 1 10.08408111 -5.314212805 4.41508908 0.945110622 0.833354285 0.388737328 0.075579604 0.20982271 8.757196898 0.011308088 0.02681141 4.85E-06 5.314212805 -0.111756337 AEPEDHYFLLTEPPLNTPENR ddPTM_HeLa_Curcumin_4h_R1 2 AEPEDHYFLLTEPPLNTPENR 21 0 B4DXW1;P61158;F8WDR7 B4DXW1 ACTR3 Actin-related protein 3 0 0 ; ; 109.37 3.51E-05 16424200 5963.8 4992.6 5150.8 5061.4 5934.7 7448.7 4815.2 5859.1 5847.6 5878.9 FALSE FALSE TRUE 5491.758937 5424.138097 5341.693179 5040.457268 5863.932579 5903.755656 4950.301553 7645.512618 5206.13291 6083.191337 0.902775966 0.891659952 0.878107047 0.828587659 0.963956623 0.970503035 0.813767195 1.256825931 0.855822647 1 12.57061267 -4.248455987 24.99881342 0.930375438 1.25682614 0.716201235 0.064880249 978.5686652 1884148.78 0.009379216 0.232496093 5.64E-05 4.248455987 0.326450702 AEPPKAPEQEQAAPGPAAGGEAPK ddPTM_HeLa_Curcumin_4h_R1 2 AEPPKAPEQEQAAPGPAAGGEAPK 24 1 P80723 P80723 BASP1 Brain acid soluble protein 1 0 0 ; ; 237.18 2.71E-41 11820800 6052.9 4539.9 4344.9 5928.4 4616.6 8140.5 6048.9 6520 7721.7 5198 FALSE FALSE TRUE 5573.806578 4932.308727 4505.925816 5903.869852 4561.55006 6452.068538 6218.615854 8507.917986 6874.648829 5378.630113 1.036287393 0.917019506 0.837745991 1.097653069 0.848087703 1.199574688 1.156170944 1.581800162 1.278141215 1 12.39302306 -3.807966247 1.056643882 0.994377593 2.504373366 0.624306881 0.130958613 1.323122491 0.60608448 0.013635132 2.82435504 0.000155609 3.807966247 1.509995773 AEPSEVDMNS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 AEPSEVDMNSPK 12 0 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 0 AEPS(0.001)EVDMNS(0.999)PK;AEPSEVDMNS(1)PK;AEPSEVDMNS(1)PK ;; 217.19 2.78E-13 570529000 19233.8 15636 19015.5 19764.9 17946.8 22410.5 20633.8 6601.2 19540.5 16576.8 TRUE FALSE FALSE 17711.42443 16987.50617 19720.23116 19683.11808 17732.79613 17762.30968 21212.72889 8613.875492 17396.95604 17152.84257 1.032564974 0.990360991 1.14967715 1.147513481 1.03381093 1.035531552 1.236688835 0.502183557 1.014231663 1 14.06616006 -4.248641524 24.96905444 1.045396873 0.502183206 0.815997691 0.080219781 683.4624412 1333435.696 0.011214266 0.276913539 5.64E-05 4.248641524 -0.543213667 AEPVEVVAPR ddPTM_HeLa_Curcumin_4h_R1 1 AEPVEVVAPR 10 0 P09874 P09874 PARP1 Poly [ADP-ribose] polymerase 1 0 0 113.26 0.0043784 3411300 810.38 790.66 792 679.75 696.99 903.38 737.37 852.07 775.35 738.25 FALSE FALSE TRUE 746.2375679 859.0011273 821.3522167 676.9373746 688.6788495 716.0088048 758.0586177 1111.862221 690.2960448 763.9041325 0.976873322 1.124488127 1.075203264 0.88615488 0.901525231 0.937301913 0.992347842 1.45549968 0.903642244 1 9.577247786 -4.261598593 7.833148222 0.987515305 1.459676092 0.791475864 0.073447008 0.031314192 21.64257312 0.009825613 0.077996619 5.48E-05 4.261598593 0.472160787 DESTDS(ph)GLSMSSYSVPR ddPTM_HeLa_Curcumin_4h_R1 1 DESTDSGLSMSSYSVPR 17 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 0 DES(0.001)T(0.018)DS(0.926)GLSMS(0.005)S(0.015)Y(0.01)S(0.025)VPR 101.3 0.0019358 7015200 2251 3519.5 2734.8 3764.7 2021.3 741.94 878.09 816.34 3245.5 3802.7 TRUE FALSE FALSE 2072.830975 3823.709897 2836.154094 3749.122669 1997.197318 588.0532806 902.7268421 1065.238308 2889.47677 3934.843542 0.526788665 0.971756528 0.720779381 0.952800951 0.507567149 0.149447691 0.229418739 0.270719356 0.734330791 1 11.94209056 -5.509995505 3.955025831 0.793541217 0.224387286 0.792095954 0.138117241 0.1008915 3.545562693 0.027365956 0.060680963 3.09E-06 5.509995505 -0.56915393 down AEQGS(ph)EEEGEGEEEEEEGGESK ddPTM_HeLa_Curcumin_4h_R1 3 AEQGSEEEGEGEEEEEEGGESK 22 0 Q5STZ8;Q8NE71 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 0 AEQGS(1)EEEGEGEEEEEEGGESK;AEQGS(1)EEEGEGEEEEEEGGESK;AEQGS(1)EEEGEGEEEEEEGGESK ;; 148.35 4.48E-06 33352300 11939.4 9470.9 12070.9 11136.7 13193.7 13148.2 11090.2 9762.7 10285.3 9899.2 TRUE FALSE FALSE 10994.38389 10289.52239 12518.25817 11090.61929 13036.37374 10421.11511 11401.36116 12739.30229 9157.028323 10243.19646 1.073335255 1.004522605 1.222104664 1.08273031 1.272686099 1.017369446 1.113066727 1.243684267 0.893961993 1 13.32237837 -7.368921773 0.487592991 1.006955632 1.15945818 0.404232465 0.089470763 0.713200844 0.416651414 0.03361317 0.036070781 4.28E-08 7.368921773 0.152502548 AEQLVLS(ph)GADSDEDTSR ddPTM_HeLa_Curcumin_4h_R1 1 AEQLVLSGADSDEDTSR 17 0 H7C1N2;J3KR05;O75128-2 H7C1N2 COBL Protein cordon-bleu 1 0 AEQLVLS(0.584)GADS(0.416)DEDTSR 205.98 9.64E-11 10051000 2436.7 2080.6 1720.5 1971.1 2259.5 2930.2 1925.7 864.34 2250.6 1879.4 TRUE FALSE FALSE 2243.832624 2260.437793 1784.263244 1962.94411 2232.556938 2322.44349 1979.729959 1127.873287 2003.714811 1944.70901 1.153814073 1.162352713 0.91749626 1.009376776 1.148015938 1.194237018 1.018008324 0.579970207 1.030341712 1 10.92533858 -4.27228337 4.092280606 1.0776059 0.54249326 0.756913226 0.083911527 0.085788819 3.084942165 0.01281187 0.132566189 5.34E-05 4.27228337 -0.53511264 AEQLVLSGADS(ph)DEDTSR ddPTM_HeLa_Curcumin_4h_R1 2 AEQLVLSGADSDEDTSR 17 0 H7C1N2;J3KR05;O75128-2 H7C1N2 COBL Protein cordon-bleu 1 0 AEQLVLS(0.017)GADS(0.982)DEDTSR;AEQLVLS(0.001)GADS(0.998)DEDT(0.002)SR ; 224.12 2.04E-16 35782000 4297.6 4124.7 4541 4449.2 4227.9 4899.1 3800.2 1816.67 4942.6 3764.5 TRUE FALSE FALSE 3957.440425 4481.220689 4709.293455 4430.790389 4177.485054 3882.971436 3906.823384 2370.56432 4400.409146 3895.316095 1.01594847 1.150412593 1.208963109 1.137466198 1.072438013 0.996830897 1.002954135 0.608567896 1.129666769 1 11.92752469 -4.206312579 2.710255691 1.045471071 0.486006356 0.761760651 0.077219846 0.258534177 2.198443398 0.012250021 0.342151524 6.22E-05 4.206312579 -0.559464715 AEQLVLSGADSDEDT(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 AEQLVLSGADSDEDTSR 17 0 H7C1N2;J3KR05;O75128-2 H7C1N2 COBL Protein cordon-bleu 1 0 AEQLVLSGADS(0.026)DEDT(0.972)S(0.002)R 329.78 2.17E-130 27047000 5219.1 4406.6 4817 4866.6 4689.2 5793.9 4519.3 1824.9 5459.6 4414.2 TRUE FALSE FALSE 4806.002728 4787.486869 4995.522257 4846.463299 4633.284353 4592.179829 4646.099395 2381.303609 4860.695539 4567.593121 1.052195894 1.048142149 1.093688103 1.061054076 1.014382023 1.005382859 1.017187668 0.521347578 1.064169993 1 12.15721843 -4.260678968 5.660167735 1.031943832 0.504230955 0.966344476 0.02899537 0.020078593 2.641522368 0.004551422 0.040688339 5.49E-05 4.260678968 -0.527712877 SESLDPDS(ph)SMDTTLILK ddPTM_HeLa_Curcumin_4h_R1 1 SESLDPDSSMDTTLILK 17 0 H0Y2V6;Q5SW79;Q5SW79-3;Q5SW79-2 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 0 S(0.002)ES(0.172)LDPDS(0.585)S(0.188)MDT(0.045)T(0.009)LILK 130.66 0.00040043 26035000 3771.5 2801.9 2690.1 3140.4 3056.1 8192.8 11340 11020 2700.1 2571.4 TRUE FALSE FALSE 3472.981795 3044.083751 2789.797472 3127.405857 3019.658004 6493.520928 11658.16988 14379.94727 2403.905785 2660.755959 1.305261305 1.144067249 1.048498064 1.17538245 1.134887247 2.440479709 4.381525424 5.404459294 0.903467219 1 11.37762048 -4.783500969 1.744701284 1.132511101 5.493484106 0.993057112 0.126934696 0.024670973 0.13189462 0.02001785 0.127739259 1.65E-05 4.783500969 4.360973005 up SPSLSPSPPS(ph)PLEKTPLGER ddPTM_HeLa_Curcumin_4h_R1 1 SPSLSPSPPSPLEKTPLGER 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(0.001)PS(0.001)LS(0.009)PS(0.263)PPS(0.711)PLEKT(0.015)PLGER 48.852 0.018357 118190000 636.3 404.2 602.93 592.94 333.6 1172.2 1121.9 1127.7 739.47 638.07 TRUE FALSE FALSE 585.9361836 439.1372469 625.2751162 590.4865714 329.6220379 929.0725066 1153.377495 1471.530539 658.3519911 660.242885 0.887455506 0.665114698 0.947038023 0.894347497 0.499243605 1.407167768 1.746898786 2.22877152 0.997136063 1 9.366853039 -4.782258534 2.061834692 0.895179643 2.147921626 0.868532404 0.17987167 0.087071347 0.689722875 0.025253057 0.137846027 1.65E-05 4.782258534 1.252741983 up AES(ph)LPLSSNLQSK ddPTM_HeLa_Curcumin_4h_R1 1 AESLPLSSNLQSK 13 0 Q8N1W1-2;Q8N1W1-5;Q8N1W1-4;Q8N1W1-3;Q8N1W1;Q8N1W1-6 Q8N1W1-2 ARHGEF28 Rho guanine nucleotide exchange factor 28 1 0 AES(1)LPLSSNLQSK 139.64 0.0010095 3566900 1144.3 1094.1 966.27 1396.8 1381.2 1538.1 963.53 494.06 1128.4 1119 TRUE FALSE FALSE 1053.727448 1188.669129 1002.080816 1391.020412 1364.730092 1219.080722 990.5640586 644.6966196 1004.617343 1157.885167 0.910044863 1.026586369 0.865440585 1.201345739 1.178640276 1.052851144 0.855494212 0.556788046 0.86763124 1 10.17727647 -4.348960143 2.827399103 0.992904911 0.518827145 0.60762407 0.110901179 0.188072084 2.265878752 0.015962007 0.183568086 4.48E-05 4.348960143 -0.474077765 GAILSEEELAAMSPT(ph)AAAVAK ddPTM_HeLa_Curcumin_4h_R1 3 GAILSEEELAAMSPTAAAVAK 21 0 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 0 GAILSEEELAAMS(0.13)PT(0.87)AAAVAK;GAILSEEELAAMS(0.399)PT(0.601)AAAVAK;GAILSEEELAAMS(0.306)PT(0.694)AAAVAK ;; 102.58 0.00010336 30055500 8565.7 6769.8 7078.7 7462.2 7595.6 12502.2 11455.7 10514.1 9000.8 6493 TRUE FALSE FALSE 7887.715807 7354.951346 7341.042849 7431.323394 7505.027431 9909.102791 11777.11611 13719.80069 8013.434759 6718.631267 1.174006355 1.094709779 1.09263964 1.106076982 1.117047079 1.47486927 1.752904073 2.042052934 1.192718344 1 12.71395164 -4.779343123 1.298980281 1.083543706 2.103265116 0.966958509 0.059173435 0.086129002 0.217386898 0.010294667 0.090587847 1.66E-05 4.779343123 1.019721411 up AES(ph)PAEKVPEESVLPLVQK ddPTM_HeLa_Curcumin_4h_R1 4 AESPAEKVPEESVLPLVQK 19 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 AES(0.999)PAEKVPEES(0.001)VLPLVQK;AES(0.951)PAEKVPEES(0.049)VLPLVQK;AES(0.983)PAEKVPEES(0.017)VLPLVQK;AES(0.98)PAEKVPEES(0.02)VLPLVQK ;;; 119.92 0.00010344 205097000 16224.5 13257.1 16494.6 15114.9 17258.7 13463.6 8491.5 9860.4 14021.1 12530.8 TRUE FALSE FALSE 14940.3137 14402.98465 17105.90439 15052.35855 17052.90127 10671.09759 8729.748636 12866.79057 12483.02041 12966.24437 1.15224681 1.110806201 1.319264384 1.160888082 1.315176607 0.822990628 0.673267323 0.992329791 0.962732157 1 13.66247305 -5.191844973 10.68607262 1.116315865 0.813337782 0.54035695 0.131491678 0.44519245 67.02573389 0.018798228 0.047977485 6.43E-06 5.191844973 -0.302978083 AES(ph)PEEVACR ddPTM_HeLa_Curcumin_4h_R1 1 AESPEEVACR 10 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 AES(1)PEEVACR 107.03 0.008887 112600000 2416.6 1981.6 2362.5 2624.5 2305.1 2277.4 1950.7 1553.5 2086.3 2089.9 TRUE FALSE FALSE 2225.32356 2152.880674 2450.056328 2613.640514 2277.613188 1805.041568 2005.431392 2027.154999 1857.43811 2162.523869 1.029039999 0.995540768 1.132961519 1.208606551 1.053219907 0.83469209 0.927356882 0.937402369 0.858921437 1 11.07850034 -5.276050492 24.72932365 1.039054139 0.90257109 0.338903187 0.089537208 515.2969042 872140.4232 0.011186342 0.025118871 5.30E-06 5.276050492 -0.136483049 AES(ph)PESSAIEST(ph)QSTPQK ddPTM_HeLa_Curcumin_4h_R1 1 AESPESSAIESTQSTPQK 18 0 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 2 0 AES(0.982)PES(0.015)S(0.003)AIES(0.026)T(0.891)QS(0.022)T(0.061)PQK 129.77 0.0002266 30422000 4321 3408.9 3699.5 4799.7 4646.7 5258.3 4943.1 2360.7 3894.7 3466.3 TRUE FALSE FALSE 3978.988291 3703.550126 3836.606724 4779.840113 4591.291137 4167.669307 5081.790082 3080.466563 3467.461154 3586.753667 1.109356443 1.032563279 1.069659943 1.332636851 1.280068709 1.161961398 1.416821604 0.858845309 0.966740812 1 11.80846295 -6.38857146 7.332254599 1.051686177 1.22245771 0.268068891 0.142388749 0.259063358 14.37740735 0.019834924 0.0303359 4.09E-07 6.38857146 0.170771532 AES(ph)PESSAIESTQS(ph)TPQKGR ddPTM_HeLa_Curcumin_4h_R1 1 AESPESSAIESTQSTPQKGR 20 1 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 2 0 AES(0.426)PES(0.251)S(0.323)AIEST(0.001)QS(0.678)T(0.321)PQKGR 109.03 0.00019577 117580000 5684 4187.1 4979.3 6301.4 4473.2 7003.2 5570.3 3046 7136.6 5814.5 TRUE FALSE FALSE 5234.105402 4549.014267 5163.837238 6275.326476 4419.860012 5550.657378 5726.587626 3974.711378 6353.732835 6016.553442 0.869950787 0.756083082 0.858271648 1.043010178 0.734616596 0.922564294 0.951805329 0.660629282 1.056041951 1 12.55472157 -8.90503332 0.754454348 1.000703315 0.855625783 0.290185111 0.10784018 0.803796393 0.849831116 0.065598263 0.02130299 1.24E-09 8.90503332 -0.145077532 AES(ph)PESSAIESTQST(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 1 AESPESSAIESTQSTPQK 18 0 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 2 0 AES(0.997)PES(0.003)SAIESTQS(0.049)T(0.95)PQK 260.11 6.21E-42 60489000 6145.3 5102.4 5440.8 6223.9 6409.8 6436.5 5851.1 3168 5331.4 4789.9 TRUE FALSE FALSE 5658.893021 5543.42872 5642.440834 6198.147151 6333.367321 5101.497346 6015.266119 4133.908616 4746.558759 4956.348668 1.141746354 1.118450111 1.138426937 1.250547039 1.277829254 1.029285405 1.2136487 0.834063318 0.957672488 1 12.27506197 -9.139318681 0.805154009 0.996335299 1.135185067 0.181067471 0.120258329 1.00385778 1.130497907 0.086463999 0.022633843 7.26E-10 9.139318681 0.138849768 AES(ph)PESSAIESTQST(ph)PQKGR ddPTM_HeLa_Curcumin_4h_R1 2 AESPESSAIESTQSTPQKGR 20 1 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 2 0 AES(0.396)PES(0.266)S(0.338)AIES(0.004)T(0.02)QS(0.401)T(0.576)PQKGR;AES(0.998)PES(0.001)S(0.001)AIESTQS(0.211)T(0.788)PQKGR ; 158.12 1.96E-05 113886000 8980.3 6646.2 7152.6 9092.2 7232.5 11110.7 9028.6 4571.7 11492.7 9194.3 TRUE FALSE FALSE 8269.499779 7220.667913 7417.681648 9054.578886 7146.257161 8806.215577 9281.918217 5965.590284 10231.97956 9513.801241 0.869210904 0.758967707 0.779675911 0.951730928 0.751146359 0.925625347 0.975626669 0.627045923 1.075488052 1 13.21580617 -8.632019385 0.786389551 0.993143518 0.835233046 0.365795151 0.104950386 0.574869874 0.716186215 0.047107243 0.020820657 2.33E-09 8.632019385 -0.157910472 AES(ph)PESSAIESTQSTPQK ddPTM_HeLa_Curcumin_4h_R1 2 AESPESSAIESTQSTPQK 18 0 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 AES(0.974)PES(0.023)S(0.003)AIESTQSTPQK;AES(0.983)PES(0.017)SAIESTQSTPQK ; 245.04 3.69E-32 606590000 13901.3 10382.7 12505.2 14698.1 12609.1 13464.6 11227.9 10037.9 15661.2 13879.8 TRUE FALSE FALSE 12800.99744 11280.13432 12968.65371 14637.28316 12458.74472 10671.89018 11542.92466 13098.4095 13943.20554 14362.12202 0.891302652 0.785408612 0.902976155 1.019158808 0.867472418 0.743058036 0.803706071 0.912010738 0.970831854 1 13.8099813 -13.52287875 0.142608948 1.515714801 0.810780562 0.294744393 0.073430027 62.44305974 0.616290965 8.963371369 0.212667794 3.00E-14 13.52287875 -0.704934239 AES(ph)PGPGSR ddPTM_HeLa_Curcumin_4h_R1 1 AESPGPGSR 9 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 0 AES(0.937)PGPGS(0.063)R 98.04 0.014279 23891000 7292.2 12677 7458.4 6093.9 5216.5 4114.5 2974.7 1680.8 5351.9 7372 TRUE FALSE FALSE 6715.014675 13772.74339 7734.814865 6068.685056 5154.296645 3261.10632 3058.162076 2193.268183 4764.80996 7628.176451 0.880290947 1.805509283 1.013979542 0.795561704 0.675691848 0.427507982 0.400903426 0.287521952 0.624632898 1 12.8971225 -5.600736634 1.561216511 1.020367309 0.355520465 0.522351372 0.285742446 0.238997549 1.156163799 0.04227891 0.114727114 2.51E-06 5.600736634 -0.664846844 AES(ph)PSPAPPPGLR ddPTM_HeLa_Curcumin_4h_R1 3 AESPSPAPPPGLR 13 0 Q9BUA3 Q9BUA3 C11orf84 Uncharacterized protein C11orf84 1 0 AES(0.979)PS(0.021)PAPPPGLR;AES(0.681)PS(0.319)PAPPPGLR;AES(0.995)PS(0.005)PAPPPGLR ;; 166.24 0.00018129 629188700 8709 6939.1 6782.7 7823.2 7205.1 9275.5 7569.3 5633.2 7889.3 7410.5 TRUE FALSE FALSE 8019.67346 7538.884884 7034.072829 7790.829671 7119.183888 7351.656744 7781.674186 7350.736748 7023.863528 7668.014323 1.045860522 0.98315999 0.917326511 1.016016578 0.928426003 0.95874322 1.014822594 0.958623242 0.915995098 1 12.90463732 -7.062829865 6.854628302 1.021426617 0.966739234 0 0.045778926 0.191211284 17.62330805 0.005335225 0.006571123 8.65E-08 7.062829865 -0.054687382 AES(ph)PTPGMAQGMEPGAGQEGAMFVHAR ddPTM_HeLa_Curcumin_4h_R1 1 AESPTPGMAQGMEPGAGQEGAMFVHAR 27 0 A0A0A0MSQ9;Q86VX9-5;Q86VX9 A0A0A0MSQ9 MON1A Vacuolar fusion protein MON1 homolog A 1 0 AES(0.877)PT(0.123)PGMAQGMEPGAGQEGAMFVHAR 72.433 0.0001977 8752300 1717 1369.2 1658.8 1584.2 1548.6 1342.9 949.58 660.55 1738.6 1273.9 TRUE FALSE FALSE 1581.097638 1487.547547 1720.276587 1577.645 1530.133956 1064.367402 976.2226591 861.9486542 1547.87993 1318.16793 1.199466018 1.128496235 1.305051161 1.196846748 1.160803507 0.80745964 0.74059051 0.653898972 1.174266112 1 10.36431846 -5.143478952 3.367105322 1.127071818 0.708077496 0.852648615 0.081882761 0.094339615 1.981845302 0.015378239 0.043690889 7.19E-06 5.143478952 -0.418994321 AESCGS(ph)FDETESEESSK ddPTM_HeLa_Curcumin_4h_R1 1 AESCGSFDETESEESSK 17 0 A8MXB7;Q9Y343-2;Q9Y343 A8MXB7 SNX24 Sorting nexin-24 1 0 AESCGS(1)FDETESEESSK 278.39 1.26E-65 13335000 1504.7 1341.3 1176.3 1584.3 1435.4 2518 1877.4 1790.3 1486.5 1295 TRUE FALSE FALSE 1385.601407 1457.235995 1219.894713 1577.744586 1418.283792 1995.738416 1930.074791 2336.154228 1323.434669 1340.001154 1.034030011 1.087488612 0.910368405 1.177420319 1.058419829 1.489355745 1.440353082 1.743397177 0.987636962 1 10.38801853 -4.899014142 0.915667078 1.014500885 1.784798761 0.885461681 0.087340478 0.201433151 0.220811358 0.012186727 0.123612044 1.26E-05 4.899014142 0.770297876 AESEASLLNVST(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 AESEASLLNVSTPK 14 0 A0A075B754;Q96QE3-2;Q96QE3 A0A075B754 ATAD5 ATPase family AAA domain-containing protein 5 1 0 AESEASLLNVS(0.001)T(0.999)PK 161.48 0.00078538 10171000 3154 2490.8 2922.8 3026.4 2951.9 4031.8 3640.3 1493.8 4462.7 2817.6 TRUE FALSE FALSE 2904.357572 2706.093653 3031.121539 3013.877559 2916.70052 3195.559232 3742.437021 1949.252743 3973.152975 2915.51139 0.996174318 0.928171182 1.039653472 1.033738907 1.000407863 1.09605445 1.283629703 0.668580047 1.362763661 1 11.50953324 AESPES(ph)SAIESTQSTPQK ddPTM_HeLa_Curcumin_4h_R1 2 AESPESSAIESTQSTPQK 18 0 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 AES(0.044)PES(0.956)SAIESTQSTPQK;AES(0.415)PES(0.464)S(0.122)AIESTQSTPQK ; 283.22 1.60E-67 24471600 9783.3 6744.9 8367.2 9712.5 8234.2 9848.5 6539.7 6747.2 10742.8 9831.3 TRUE FALSE FALSE 9008.941482 7327.899101 8677.295793 9672.312248 8136.012543 7805.810085 6723.186381 8804.39022 9564.341717 10172.93694 0.885579212 0.720332697 0.852978431 0.950788578 0.799770272 0.76731136 0.660889419 0.865471817 0.940175071 1 13.31244863 -8.744826398 0.182257238 1.138609284 0.714331223 0.388888919 0.079690816 4.448181128 0.334313061 0.542839573 0.204017143 1.80E-09 8.744826398 -0.424278061 AESPESS(ph)AIESTQST(ph)PQKGR ddPTM_HeLa_Curcumin_4h_R1 1 AESPESSAIESTQSTPQKGR 20 1 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 2 0 AES(0.361)PES(0.037)S(0.602)AIESTQS(0.14)T(0.859)PQKGR 114.64 0.00024262 107670000 9107.7 5737.4 7544.5 8460 6032 9312.2 8402.1 3827.9 10975 8080.7 TRUE FALSE FALSE 8386.815935 6233.315291 7824.105807 8424.994762 5960.07234 7380.74475 8637.840313 4995.009089 9771.069958 8361.503724 1.003027232 0.745477787 0.935729513 1.007593256 0.712799101 0.882705431 1.033048671 0.597381674 1.168578079 1 13.0295467 -1.000000014 0.157920356 1.043708881 0.005409158 0.324791254 0.135857516 64.45341629 0.646676197 0.228587967 15.58945662 0.099999997 1.000000014 -1.038299723 AESPESSAIEST(ph)QSTPQKGR ddPTM_HeLa_Curcumin_4h_R1 1 AESPESSAIESTQSTPQKGR 20 1 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 AES(0.003)PES(0.02)S(0.02)AIES(0.073)T(0.681)QS(0.102)T(0.102)PQKGR 55.631 0.019064 6406000 1455 1391.3 1318.8 1732.3 1443.8 1997.4 1831.5 1491.4 2230 1797.2 TRUE FALSE FALSE 1339.835215 1511.557772 1367.675888 1725.132202 1426.583628 1583.116725 1882.886961 1946.120994 1985.374579 1859.652566 0.720476093 0.812817297 0.735446993 0.927663711 0.767123738 0.85129704 1.012493944 1.046497088 1.067605108 1 10.8608174 -4.733492291 4.751508634 0.847830583 1.036219546 0.281715916 0.107057567 0.179879332 9.665604852 0.015831007 0.060001857 1.85E-05 4.733492291 0.188388962 AGTPIRDS(ph)HSPDLQLPTPEVIPSSGSK ddPTM_HeLa_Curcumin_4h_R1 1 AGTPIRDSHSPDLQLPTPEVIPSSGSK 27 1 H3BPE1;H3BQK9;H0Y6T5;H0Y4F5 H3BPE1 MACF1 1 0 AGT(0.04)PIRDS(0.491)HS(0.469)PDLQLPTPEVIPSSGSK 101.59 3.49E-07 12742000 1614.5 1482.8 1046 1298 725.53 773.43 315.99 177.6 1860.6 1551.4 TRUE FALSE FALSE 1486.710621 1610.966625 1084.76568 1292.62922 716.8785286 613.0118996 324.855829 231.7494224 1656.496835 1605.311035 0.926119979 1.00352305 0.675735516 0.805220417 0.446566748 0.381864876 0.202363169 0.144364187 1.031885285 1 10.64863714 -5.498145012 0.655333815 0.978337788 0.050220778 0.945115162 0.076355607 0.146716536 0.096381168 0.013132749 0.0759413 3.18E-06 5.498145012 -0.92811701 down AESSSGGGTVPSSAGILEQGPS(ph)PGDGSPPKPKDPVSAAVPAPGR ddPTM_HeLa_Curcumin_4h_R1 1 AESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGR 44 2 Q68EM7-5;Q68EM7-7;Q68EM7-3;Q68EM7-6;Q68EM7 Q68EM7-5 ARHGAP17 Rho GTPase-activating protein 17 1 0 AESSSGGGTVPSS(0.001)AGILEQGPS(0.722)PGDGS(0.246)PPKPKDPVS(0.032)AAVPAPGR 71.46 1.63E-08 259190000 1897.1 1520.6 1563.2 2151.7 1590.7 2093.7 1265.7 1761.2 2476.9 1893.7 TRUE FALSE FALSE 1746.942533 1652.033888 1621.133567 2142.796836 1571.731941 1659.443019 1301.212136 2298.181772 2205.190267 1959.505934 0.891521941 0.843086954 0.827317508 1.093539345 0.802106242 0.846868075 0.664051133 1.172837363 1.125380755 1 10.93627423 -8.983056739 0.70808171 1.004020753 0.882873368 0.148743013 0.143603342 1.444186543 1.282970899 0.09853505 0.027693101 1.04E-09 8.983056739 -0.121147385 AESSSGGGTVPSSAGILEQGPSPGDGS(ph)PPKPK ddPTM_HeLa_Curcumin_4h_R1 2 AESSSGGGTVPSSAGILEQGPSPGDGSPPKPK 32 1 Q68EM7-5;Q68EM7-7;Q68EM7-3;Q68EM7-6;Q68EM7 Q68EM7-5 ARHGAP17 Rho GTPase-activating protein 17 1 0 AESSSGGGTVPS(0.001)S(0.001)AGILEQGPS(0.027)PGDGS(0.972)PPKPK;AESSSGGGTVPSSAGILEQGPS(0.337)PGDGS(0.663)PPKPK ; 112.9 4.47E-12 216350000 6422.8 5890.7 6643.4 6411.8 7656 7422.8 6068.5 6013.6 6078.1 5468.7 TRUE FALSE FALSE 5914.428603 6399.86586 6889.610248 6385.269671 7564.7072 5883.227608 6238.765777 7847.118957 5411.347637 5658.736918 1.045185293 1.130970736 1.217517327 1.128391329 1.33681903 1.039671519 1.102501471 1.386726238 0.95628189 1 12.46626435 -7.191544166 1.73028202 1.016926218 1.194270352 0.446936274 0.099591848 0.250344745 1.425891353 0.017163745 0.020914483 6.43E-08 7.191544166 0.177344134 AESSSGGGTVPSSAGILEQGPSPGDGS(ph)PPKPKDPVSAAVPAPGR ddPTM_HeLa_Curcumin_4h_R1 1 AESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGR 44 2 Q68EM7-5;Q68EM7-7;Q68EM7-3;Q68EM7-6;Q68EM7 Q68EM7-5 ARHGAP17 Rho GTPase-activating protein 17 1 0 AESSSGGGTVPSS(0.002)AGILEQGPS(0.26)PGDGS(0.707)PPKPKDPVS(0.03)AAVPAPGR 59.491 9.93E-06 222540000 3395.9 2929.2 2958.6 2845.2 2655.9 3497.4 2714.8 2402.2 4123.1 3258.2 TRUE FALSE FALSE 3127.110932 3182.386996 3068.248319 2833.427316 2624.230127 2771.999816 2790.969981 3134.619722 3670.806245 3371.422207 0.927534654 0.943930128 0.910075372 0.840424943 0.778374812 0.822204887 0.827831642 0.929761842 1.088800518 1 11.71914159 -6.601458661 1.433488647 0.966672287 0.83377014 0.611685477 0.055192806 0.183837732 0.760636128 0.007712676 0.012288562 2.50E-07 6.601458661 -0.132902147 GYYS(ph)PY(ph)SVSGSGSTAGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 3 0 GYY(0.013)S(0.982)PY(0.494)S(0.504)VS(0.005)GS(0.002)GS(0.001)T(0.001)AGS(0.997)R 110.37 0.00046837 17154000 2253.6 2153.3 2900.2 2581.6 2957 4348.8 5584.6 4902.5 2434.8 2654.7 TRUE FALSE FALSE 2075.225182 2339.421657 3007.683963 2570.918023 2921.739706 3446.809859 5741.288846 6397.249682 2167.708532 2746.950627 0.755465046 0.85164314 1.094917372 0.935917085 1.063630222 1.254776778 2.090058987 2.328854992 0.789132688 1 11.42361526 -4.770751928 1.581397866 0.902348382 2.438688671 0.959295178 0.104717531 0.073080703 0.304293226 0.017780943 0.128721455 1.70E-05 4.770751928 1.536340289 up AVTPVPTKT(ph)EEVSNLK ddPTM_HeLa_Curcumin_4h_R1 1 AVTPVPTKTEEVSNLK 16 1 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 0 AVT(0.022)PVPT(0.37)KT(0.594)EEVS(0.014)NLK 76.358 0.0135 1188100000 5633.6 4136 4495.8 4414.1 2727.8 2063.4 994.22 527.42 5279.8 4147.5 TRUE FALSE FALSE 5187.694615 4493.49741 4662.418303 4395.835624 2695.272767 1635.427581 1022.115137 688.2279301 4700.619149 4291.625316 1.208794858 1.047038611 1.086399198 1.024282247 0.628030773 0.381074176 0.238165045 0.160365335 1.095300452 1 12.06730841 -5.468490503 1.403919462 1.09977567 0.190009662 0.976070055 0.058207152 0.061095667 0.230924601 0.012788861 0.041268168 3.40E-06 5.468490503 -0.909766008 down AET(ph)PTESVS(ph)EPEVATK ddPTM_HeLa_Curcumin_4h_R1 2 AETPTESVSEPEVATK 16 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 2 0 AET(0.944)PT(0.056)ES(0.363)VS(0.633)EPEVAT(0.004)K;AET(0.997)PT(0.003)ES(0.113)VS(0.887)EPEVATK ; 177.04 9.82E-05 29546000 13481 12057.1 12966.6 12851 14882.5 14360.3 11818.4 9918.2 12490 11860.3 TRUE FALSE FALSE 12413.96462 13099.262 13447.1536 12797.82597 14705.03591 11381.81191 12149.9925 12942.21352 11119.87825 12272.44454 1.011531532 1.067371863 1.09571924 1.042809843 1.198215715 0.927428261 0.990022196 1.054575026 0.906085027 1 13.58313503 -7.355096483 5.328823431 1.005079266 1.053103063 0.168338685 0.072665977 0.40189687 17.88555619 0.011253907 0.012823346 4.41E-08 7.355096483 0.048023796 AET(ph)PTESVSEPEVATK ddPTM_HeLa_Curcumin_4h_R1 2 AETPTESVSEPEVATK 16 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 AET(1)PTESVSEPEVATK;AET(0.992)PT(0.008)ESVSEPEVATK ; 276.34 9.30E-65 132907000 10793.4 9059.4 10928.4 9941.7 11507.7 11560.2 9629.8 9679 9897.6 8432.9 TRUE FALSE FALSE 9939.091001 9842.454168 11333.41612 9900.56388 11370.47819 9162.48421 9899.986271 12630.08254 8811.858043 8725.942647 1.139027771 1.127953112 1.298818543 1.134612532 1.303065887 1.050028012 1.134546337 1.447417552 1.009845973 1 13.09109528 -13.52287875 0.085804738 0.279317366 1.398068872 0.415580787 0.10401928 115.2730404 0.753446899 15.31626299 1.45916105 3.00E-14 13.52287875 1.118751506 AETAAK(ac)HGEAQVK ddPTM_HeLa_Curcumin_4h_R1 1 AETAAKHGEAQVK 13 1 P18669;Q8N0Y7 P18669 PGAM1;PGAM4 Phosphoglycerate mutase 1;Probable phosphoglycerate mutase 4 0 1 AETAAK(1)HGEAQVK 127.71 0.0018905 1583900 1797.3 1841 1491.8 1628.7 1558.9 3092.8 2137.8 2089.1 1984.2 1736.3 FALSE TRUE FALSE 1655.041808 2000.127837 1547.08742 1621.960871 1540.311136 2451.318417 2197.780914 2726.056973 1766.538224 1796.636296 0.92118912 1.113262512 0.861102174 0.902776413 0.857330523 1.36439324 1.223275362 1.517311533 0.983247543 1 10.81108267 -5.253708157 24.95073742 0.955037694 1.353821614 0.797156609 0.096944878 186.0262172 600354.9022 0.013000324 0.032461693 5.58E-06 5.253708157 0.39878392 AETPTES(ph)VSEPEVATKQELQEEEEQTKPPR ddPTM_HeLa_Curcumin_4h_R1 1 AETPTESVSEPEVATKQELQEEEEQTKPPR 30 2 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 AET(0.109)PT(0.122)ES(0.422)VS(0.346)EPEVAT(0.001)KQELQEEEEQTKPPR 55.442 0.0008721 7076700 1505 1233.2 1409 1309.1 1183.6 1492.7 1112.7 1096.1 1676.4 1606.3 TRUE FALSE FALSE 1385.877662 1339.792313 1461.218779 1303.683291 1169.486343 1183.097194 1143.919367 1430.295844 1492.503114 1662.118805 0.833801806 0.806074938 0.879130165 0.784350244 0.703611763 0.711800619 0.688229604 0.860525637 0.897952125 1 10.69880779 -8.67991319 0.269814627 1.082773108 0.719590926 0.541587739 0.063430263 1.281668381 0.182020809 0.163095269 0.051019533 2.09E-09 8.67991319 -0.363182182 AETSEGSGSAPAVPEASAS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 AETSEGSGSAPAVPEASASPK 21 0 A0A087WVW7;A0A0D9SFX7;B5MCB4;I6LM39;A0A087X1U4;P51608;P51608-2 A0A087WVW7 MECP2 Methyl-CpG-binding protein 2 1 0 AETSEGSGSAPAVPEAS(0.008)AS(0.992)PK;AETSEGSGSAPAVPEASAS(1)PK ; 328 1.37E-138 67690000 7171.9 4708.1 6723 7473 9308.7 9081.3 7914 4540.2 6475.3 5137.4 TRUE FALSE FALSE 6604.236547 5115.047185 6972.160294 7442.078706 9197.699832 7197.736013 8136.045541 5924.486079 5764.97579 5315.924268 1.24234963 0.9622122 1.311561253 1.399959505 1.730216491 1.353995213 1.530504411 1.114479022 1.084472897 1 12.37610484 -6.537486273 4.026239974 1.106196634 1.439963011 0.510970455 0.161333841 0.143139868 5.299465326 0.02632569 0.038856689 2.90E-07 6.537486273 0.333766377 AEVIWTSSDHQVLS(ph)GKT(ph)T(ph)T(ph)TNSK ddPTM_HeLa_Curcumin_4h_R1 1 AEVIWTSSDHQVLSGKTTTTNSK 23 1 Q9NZQ7-2;Q9NZQ7 Q9NZQ7-2 CD274 Programmed cell death 1 ligand 1 4 0 AEVIWT(0.006)S(0.024)S(0.116)DHQVLS(0.856)GKT(0.703)T(0.738)T(0.738)T(0.409)NS(0.409)K 50.883 0.0090818 0 911.89 871.75 574.17 804.59 753.75 836.3 861.64 918.8 684.78 944.92 TRUE FALSE FALSE 839.7129443 947.1001856 595.4492453 801.2608198 744.7620235 662.841953 885.8152994 1198.93789 609.6613472 977.7558997 0.858816546 0.968646864 0.608995809 0.819489629 0.761705477 0.677921712 0.905967737 1.226213916 0.623531239 1 9.933330526 -8.76917641 0.721496661 0.997605875 0.838326615 0 0.1975989 1.158125357 1.160215165 0.098289471 0.035489297 1.70E-09 8.76917641 -0.15927926 AEVLSEEPILK ddPTM_HeLa_Curcumin_4h_R1 2 AEVLSEEPILK 11 0 Q7L1Q6-2;Q7L1Q6;Q7L1Q6-4;Q7L1Q6-3 Q7L1Q6-2 BZW1 Basic leucine zipper and W2 domain-containing protein 1 0 0 ; ; 119.16 0.0022136 2910900 2108.42 1670.29 2067.7 2207.97 2360.8 1550.34 1870.26 1288.12 1656.54 1775.93 FALSE FALSE TRUE 1941.536332 1814.662425 2144.330781 2198.834005 2332.649002 1228.782008 1922.734462 1680.861858 1474.821706 1837.643435 1.056535939 0.987494304 1.16689165 1.196550954 1.269369758 0.668672706 1.046304427 0.914683353 0.80256141 1 10.84364115 -5.265078339 24.99949276 1.062105838 0.893528597 0.254552389 0.149392246 320.3155544 2200562.359 0.018209771 0.042282862 5.43E-06 5.265078339 -0.168577241 AEVSELK ddPTM_HeLa_Curcumin_4h_R1 1 AEVSELK 7 0 P67936;A0A2R8Y5V9;A0A2R8YGX3;A0A2R8YH90;A0A2R8YE05;P67936-2;K7ENT6;A0A2R8YEU4;A0A2R8YHD2;A0A5F9UN72;K7EPB9;A0A590UJT6;Q2TAC2-2;A0A494BX66;Q2TAC2 P67936 TPM4;CCDC57 Tropomyosin alpha-4 chain;Coiled-coil domain-containing protein 57 0 0 119.89 0.0095456 18932000 5470.3 4868.9 4712.8 5176.5 5203.1 6133.5 4384.3 5392.2 5854.2 5282.2 FALSE FALSE TRUE 5037.319983 5289.746021 4887.460514 5155.081015 5141.056431 4861.342961 4507.311658 7036.256957 5212.008906 5465.756057 0.92161449 0.967797678 0.894196606 0.943159731 0.940593831 0.889418209 0.824645595 1.287334613 0.953575105 1 12.41620536 -4.248845226 24.83201079 0.943394365 1.28733485 0.828091491 0.048806512 649.0231398 1279660.738 0.007626013 0.1798305 5.64E-05 4.248845226 0.343940485 AEVSQPR ddPTM_HeLa_Curcumin_4h_R1 2 AEVSQPR 7 0 P22314;P22314-2;Q5JRR9;Q5JRS0;Q5JRS2;Q5JRS1;Q5JRS3 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 0 ; ; 113.89 0.011343 2807500 2499.4 3275.2 2240.4 1883.53 1727.18 2228.9 1741.45 1965.81 1660.94 2301.9 FALSE FALSE TRUE 2301.569853 3558.293694 2323.431195 1875.736452 1706.584507 1766.601015 1790.3104 2565.17642 1478.739037 2381.890854 0.966278471 1.49389452 0.975456617 0.78749891 0.716483085 0.741680087 0.751634105 1.076949607 0.620825692 1 11.21789159 -6.328178857 5.296693983 1.030569554 0.801882224 0.166179957 0.218724733 0.225476276 12.43187011 0.027863116 0.043083861 4.70E-07 6.328178857 -0.22868733 AEVYGS(ph)ENESER ddPTM_HeLa_Curcumin_4h_R1 1 AEVYGSENESER 12 0 Q9BVS4;Q9BVS4-2 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 0 AEVYGS(1)ENESER 140.33 0.0011902 23638000 1700.1 1120.9 1446.9 1230 1605.6 1294.6 1298.3 803.18 1031.4 1006.8 TRUE FALSE FALSE 1565.535291 1217.785601 1500.523387 1224.910586 1586.454269 1026.085367 1334.726804 1048.065885 918.2580004 1041.786225 1.502741401 1.168940011 1.440337135 1.175779211 1.522821314 0.984928906 1.281190682 1.006027781 0.881426514 1 10.02484355 -5.216282762 24.999001 1.264577843 1.109763364 0.088579967 0.210682999 851.0854887 471165.2361 0.030191042 0.076972009 6.08E-06 5.216282762 -0.154814478 AFAAVPTSHPPEDAPAQPPT(ph)PGPAASPEQLSFR ddPTM_HeLa_Curcumin_4h_R1 1 AFAAVPTSHPPEDAPAQPPTPGPAASPEQLSFR 33 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 AFAAVPTSHPPEDAPAQPPT(0.893)PGPAAS(0.103)PEQLS(0.003)FR 124.31 7.42E-18 29922000 4579.8 3662.9 4091.2 4799.5 4044.1 5348.1 2425 1946.1 5695.5 3969.6 TRUE FALSE FALSE 4217.303997 3979.504754 4242.823471 4779.640941 3995.876749 4238.843774 2493.038973 2539.456931 5070.717899 4107.543305 1.026721737 0.968828436 1.032934569 1.16362521 0.972814272 1.031965693 0.606941617 0.618242278 1.234489213 1 12.00406007 -4.76091573 24.99961303 1.020173198 0.612591798 0.807314933 0.084973296 2.491617762 118917.955 0.007011376 0.023412749 1.73E-05 4.76091573 -0.4075814 AFAAVPTSHPPEDAPAQPPTPGPAAS(ph)PEQLSFR ddPTM_HeLa_Curcumin_4h_R1 2 AFAAVPTSHPPEDAPAQPPTPGPAASPEQLSFR 33 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 AFAAVPTSHPPEDAPAQPPT(0.052)PGPAAS(0.896)PEQLS(0.053)FR;AFAAVPTSHPPEDAPAQPPT(0.068)PGPAAS(0.676)PEQLS(0.256)FR ; 105.78 3.74E-14 44108000 4678.2 3983.2 3399.8 4310.2 3517.7 5115.5 2008.33 1632.23 5552.4 4025.2 TRUE FALSE FALSE 4307.915534 4327.490059 3525.799579 4292.365534 3475.753725 4054.487636 2064.678335 2129.889413 4943.315611 4165.0754 1.034294729 1.03899441 0.846515186 1.030561304 0.834499593 0.973448797 0.495712115 0.511368753 1.186849009 1 12.0241269 -4.76821918 7.17746687 0.99219005 0.501023845 0.810259413 0.094783473 0.028431682 8.151519934 0.010326295 0.034166229 1.71E-05 4.76821918 -0.491166205 AFDGAGSS(ph)LGR ddPTM_HeLa_Curcumin_4h_R1 3 AFDGAGSSLGR 11 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 0 AFDGAGS(0.004)S(0.996)LGR;AFDGAGS(0.001)S(0.999)LGR;AFDGAGS(0.002)S(0.998)LGR ;; 160.67 2.11E-06 42142000 11503.6 11001 12626.8 12867 14009.4 21314 17805.3 10348.8 13283.8 13458.3 TRUE FALSE FALSE 10593.07792 11951.87742 13094.76032 12813.75976 13842.34705 16893.23614 18304.8688 13504.10148 11826.60037 13925.97492 0.760670472 0.858243497 0.940311927 0.920133767 0.993994828 1.213073859 1.314440741 0.969706003 0.849247571 1 13.76549071 -5.479450056 2.706780478 0.888288875 1.180070398 0.605502803 0.099710559 0.158361925 2.291602933 0.017177658 0.041289453 3.32E-06 5.479450056 0.291781523 AFEEAEK ddPTM_HeLa_Curcumin_4h_R1 1 AFEEAEK 7 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 111.82 0.012704 5009800 3437.4 2971.3 3127 3314.7 3461.9 4217.5 3437.9 2877.6 3659.3 3483.6 FALSE FALSE TRUE 3165.326163 3228.125932 3242.889371 3300.98465 3420.619104 3342.742959 3534.358221 3754.966993 3257.883945 3604.654841 0.878121846 0.8955437 0.899639359 0.915756097 0.948944977 0.927340649 0.980498377 1.041699458 0.90379914 1 11.81564541 -4.404009716 2.074118092 0.932429936 1.056021876 0.544352607 0.033850716 0.474276051 2.770026678 0.006991023 0.097618112 3.94E-05 4.404009716 0.123591939 AFFDEEEDHWK ddPTM_HeLa_Curcumin_4h_R1 2 AFFDEEEDHWK 11 0 O15066-2;O15066 O15066-2 KIF3B "Kinesin-like protein KIF3B;Kinesin-like protein KIF3B, N-terminally processed" 0 0 ; ; 123.11 0.0030285 8402700 6299.5 5317 5649.7 6030.1 5566.8 7136.3 5147.7 5072.7 6456.8 5215.5 FALSE FALSE TRUE 5800.887928 5776.577788 5859.082852 6005.149044 5500.419546 5656.150937 5292.130608 6619.342878 5748.505194 5396.738237 1.07488777 1.070383171 1.085671121 1.112736764 1.019211847 1.048068424 0.980616509 1.226545107 1.065181401 1 12.397872 -9.156054985 0.73961955 0.995904397 1.072886772 0.028128292 0.064304594 1.074216595 0.979968309 0.049744627 0.011769286 6.98E-10 9.156054985 0.076982375 AFFSEVERR ddPTM_HeLa_Curcumin_4h_R1 2 AFFSEVERR 9 1 Q9UQ80;Q9UQ80-2;F8VR77 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 0 ; ; 123.98 0.0076248 28975000 3282.5 2670.4 2498.2 2859.6 2648.4 3589.5 2467.9 2998.7 4078.5 2960 FALSE FALSE TRUE 3022.686661 2901.217477 2590.78549 2847.767733 2616.81956 2844.997238 2537.142632 3912.989826 3631.098754 3062.85978 0.986883788 0.94722504 0.8458714 0.929774112 0.854371322 0.928869567 0.828357422 1.277560877 1.185525625 1 11.58066361 -7.22894176 4.0187632 0.994104336 0.931013487 0.070194376 0.13437088 0.516812849 18.64737376 0.018818332 0.022663002 5.90E-08 7.22894176 -0.063090849 AFGFSHLEALLDDSK ddPTM_HeLa_Curcumin_4h_R1 1 AFGFSHLEALLDDSK 15 0 J3KR44;F5GYJ8;Q96FW1;F5GYN4;F5H6Q1 J3KR44 OTUB1 Ubiquitin thioesterase OTUB1 0 0 73.722 0.019188 2632100 1419.2 1539.2 1638.9 1505.1 1526.3 2161.8 1897.5 1646.2 1607.2 1282 FALSE FALSE TRUE 1306.868822 1672.241589 1699.639076 1498.872295 1508.099869 1713.418311 1950.738743 2148.118802 1430.894181 1326.549405 0.985164079 1.260595032 1.281248229 1.129903108 1.136859181 1.291635506 1.470536066 1.619328157 1.078658794 1 10.37346269 -1 0.263994054 0.973042473 5.468831319 0.770461715 0.092284771 14.5722427 0.184073418 0.04785347 30.00355173 0.1 1 4.495788846 AFGFSHLEALLDDSKELQR ddPTM_HeLa_Curcumin_4h_R1 2 AFGFSHLEALLDDSKELQR 19 1 J3KR44;F5GYJ8;Q96FW1;F5GYN4;F5H6Q1 J3KR44 OTUB1 Ubiquitin thioesterase OTUB1 0 0 ; ; 123.42 8.63E-05 14549900 8492.6 7193.3 7438.2 7982.9 7080.9 11400.9 8232.2 7688.7 10065.7 8354.6 FALSE FALSE TRUE 7820.401749 7815.056799 7713.866235 7949.868875 6996.464892 9036.224825 8463.173376 10032.94924 8961.517893 8644.921728 0.904623777 0.904005501 0.892300298 0.919599867 0.809315007 1.045263926 0.978976287 1.16055987 1.036622213 1 13.07763719 -3.977401417 1.291355404 0.936511045 1.392970954 0.505326011 0.066792616 1.622517913 1.42906572 0.009588874 1.161690303 0.000105341 3.977401417 0.456459908 AFGPGLEGGLVNK ddPTM_HeLa_Curcumin_4h_R1 1 AFGPGLEGGLVNK 13 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 0 0 154.24 2.96E-23 0 205.59 0 162.37 198.5 159.38 295.1 166.48 160.64 196.95 0 FALSE FALSE TRUE 189.3173346 0 168.387575 197.6786596 157.4794976 233.8929335 171.1509807 209.6183965 175.3450777 0 0 AFGPGLQGGS(ph)AGSPAR ddPTM_HeLa_Curcumin_4h_R1 1 AFGPGLQGGSAGSPAR 16 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 AFGPGLQGGS(0.636)AGS(0.364)PAR 109.55 0.0016616 32379000 854.48 606.07 945.16 782.46 693.96 1140.2 858.35 591.38 918.98 673.08 TRUE FALSE FALSE 786.8470064 658.4559902 980.188461 779.2223878 685.6849802 903.7096673 882.4329909 771.6890396 818.1701932 696.4694799 1.129765236 0.945419734 1.407367429 1.118817709 0.984515474 1.297558175 1.267008844 1.108001229 1.174739478 1 9.443916323 -10.12375471 0.157365682 0.792802488 1.243158662 0 0.14046372 23.29081409 0.729809182 2.255076958 0.380690589 7.52E-11 10.12375471 0.450356174 AFGPGLQGGSAGS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 5 AFGPGLQGGSAGSPAR 16 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 AFGPGLQGGSAGS(1)PAR;AFGPGLQGGSAGS(1)PAR;AFGPGLQGGS(0.001)AGS(0.999)PAR;AFGPGLQGGSAGS(1)PAR;AFGPGLQGGSAGS(1)PAR ;;;; 228.99 8.43E-22 2981427000 8809.7 7209.67 7276.75 7527.28 7448.22 10372.22 9249.86 4992.42 8475.78 7069.48 TRUE FALSE FALSE 8112.402949 7832.841749 7546.432756 7496.13411 7359.404841 8220.904653 9509.386177 6514.585876 7546.008139 7315.143904 1.108987473 1.070770699 1.031617813 1.024741852 1.00605059 1.12381995 1.299958866 0.890561548 1.031559767 1 12.83667053 -9.474888572 1.174063575 0.999352755 1.077778274 0.036942925 0.09922474 1.059662916 2.578529384 0.068228251 0.01619113 3.35E-10 9.474888572 0.078425519 AFGS(ph)GYR ddPTM_HeLa_Curcumin_4h_R1 1 AFGSGYR 7 0 E7EX17;P23588-2;P23588;F8VP89;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 AFGS(1)GYR 101.25 0.018973 64164000 4697.9 3550.3 3545.7 3736.3 3838 6543.5 7854.2 3826.9 3558.1 2669.9 TRUE FALSE FALSE 4326.056258 3857.172112 3677.106761 3720.840181 3792.234357 5186.30434 8074.567714 4993.704193 3167.785332 2762.678826 1.56589185 1.396171019 1.330993211 1.346823288 1.372665661 1.877273714 2.922731241 1.807558716 1.146635397 1 11.43185214 -5.092375799 3.301148282 1.299662403 2.375937492 0.67860907 0.29241592 0.10457017 2.153313975 0.043510781 0.12824359 8.08E-06 5.092375799 1.07627509 AFGS(ph)GYRR ddPTM_HeLa_Curcumin_4h_R1 1 AFGSGYRR 8 1 E7EX17;P23588-2;P23588;F8VP89;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 AFGS(1)GYRR 89.029 0.010431 18883000 2913.6 2060.4 2579.8 2575.5 2064.7 4182.8 4247 2193.3 2286.6 1959 TRUE FALSE FALSE 2682.985486 2238.491795 2675.409657 2564.843263 2040.079801 3315.24013 4366.15939 2862.027073 2035.765701 2027.075104 1.32357478 1.104296427 1.31983746 1.265292666 1.006415498 1.635479674 2.153920879 1.411899869 1.004287259 1 10.98518383 -5.121499661 4.832694757 1.166323468 1.80688586 0.633745946 0.205521958 0.099851615 3.504164917 0.028190642 0.075086716 7.56E-06 5.121499661 0.640562392 AFGSGIDIKPGT(ph)PPIAGR ddPTM_HeLa_Curcumin_4h_R1 1 AFGSGIDIKPGTPPIAGR 18 1 E7EPN9;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;Q9Y520-2;A0A2R8Y7F4;A0A2R8YET2;H7C5N8;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 0 AFGSGIDIKPGT(1)PPIAGR 113.14 0.0056186 142130000 915.13 464.77 571.02 668.33 676.88 908.55 625 173.35 820.75 435.09 TRUE FALSE FALSE 842.6964949 504.9426478 592.1825035 665.5646275 668.8086481 720.1064885 642.5358179 226.203617 730.7157784 450.2093451 1.8717881 1.121573004 1.315349204 1.478344763 1.485550345 1.599492539 1.427193427 0.502440963 1.623057776 1 8.814452193 -4.261003108 23.8122427 1.416250105 0.502440508 0.581019064 0.237259318 13.9897575 763055.9301 0.044474523 0.350314301 5.48E-05 4.261003108 -0.913809597 AFHNEAQVNPER ddPTM_HeLa_Curcumin_4h_R1 3 AFHNEAQVNPER 12 0 P17987;E7EQR6;F5H282 P17987 TCP1 T-complex protein 1 subunit alpha 0 0 ;; ;; 158.25 0.00021363 13405700 4307.93 3598.2 4032.98 3560.11 4204.04 4895.89 3763.94 3206.33 4071.59 3563.76 FALSE FALSE TRUE 3966.952795 3909.212375 4182.445787 3545.379208 4153.909569 3880.427226 3869.546026 4183.925257 3624.946764 3687.600395 1.075754521 1.060096528 1.134191707 0.961432593 1.126453282 1.052290598 1.049339845 1.134592908 0.983009647 1 11.84846661 -9.237060966 0.675443881 0.992278643 1.07325413 0.304537296 0.049404924 1.02999799 0.723695635 0.048980053 0.00960209 5.79E-10 9.237060966 0.080975487 AFHNEAQVNPERK ddPTM_HeLa_Curcumin_4h_R1 1 AFHNEAQVNPERK 13 1 P17987;E7EQR6;F5H282 P17987 TCP1 T-complex protein 1 subunit alpha 0 0 64.224 0.0075643 3420700 4486.1 3433.5 3324.4 3525.4 3282.2 4286.5 3036.5 3009 4184.5 3543.6 FALSE FALSE TRUE 4131.020451 3730.276441 3447.605188 3510.812829 3243.061909 3397.431581 3121.696018 3926.430248 3725.470819 3666.739836 1.126619459 1.017327819 0.940237198 0.957475301 0.88445378 0.92655376 0.851354652 1.070823245 1.016017221 1 11.84028219 -6.851832501 3.436767224 1.060268305 0.931568749 0.385856216 0.062424892 0.166289047 3.895451147 0.011043747 0.014917844 1.41E-07 6.851832501 -0.128699556 AFITNIPFDVK ddPTM_HeLa_Curcumin_4h_R1 1 AFITNIPFDVK 11 0 A0A087X0X3;P52272-2;P52272;M0R2T0;M0QYQ7;M0R0N3;M0R019;M0R0Y6 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 0 113.69 0.0033882 387330 403.05 214.65 320.67 370.57 337.45 220.56 294.21 214.41 55.837 216.22 FALSE FALSE TRUE 371.1481672 233.2033895 332.5543123 369.0366795 333.4261291 174.8133698 302.4647408 279.782622 49.7118208 223.7336289 1.658884134 1.042326049 1.48638501 1.649446627 1.490281684 0.781345972 1.351896638 1.250516623 0.222191993 1 7.805638311 -4.226191437 19.1291413 1.311912401 1.250514115 0 0.44012853 5641.617895 3060433.761 0.043738086 5.334876589 5.94E-05 4.226191437 -0.061398286 AFKPEETSSNSDPPS(ph)PPVLNNSHPVPR ddPTM_HeLa_Curcumin_4h_R1 2 AFKPEETSSNSDPPSPPVLNNSHPVPR 27 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 0 AFKPEET(0.002)S(0.006)S(0.006)NS(0.017)DPPS(0.967)PPVLNNS(0.001)HPVPR;AFKPEETSS(0.001)NS(0.001)DPPS(0.999)PPVLNNSHPVPR ; 84.641 1.37E-05 34278000 4032.4 3066 3067.4 3573.9 3434.2 3769 2931 2352.6 3663.6 3723.4 TRUE FALSE FALSE 3713.231285 3331.011378 3181.080542 3559.112149 3393.249408 2987.266915 3013.235972 3069.89691 3261.712246 3852.787873 0.963777765 0.864571704 0.825656809 0.923775787 0.880725729 0.775352034 0.782092363 0.796798841 0.846584954 1 11.91168704 -6.299260107 0.334710718 1.011712787 0.741847764 0.269816674 0.062281966 0.650542832 0.146019589 0.023329553 0.066320323 5.02E-07 6.299260107 -0.269865023 AFLAELEQNS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 AFLAELEQNSPK 12 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 1 0 AFLAELEQNS(1)PK;AFLAELEQNS(1)PK;AFLAELEQNS(1)PK ;; 143.42 0.00098624 166321200 9610.1 7966.1 9334.8 9852.7 8862.8 10549.3 8477.9 7237 10657.5 9163.6 TRUE FALSE FALSE 8849.450444 8654.654188 9680.7559 9811.932138 8757.116898 8361.256265 8715.767057 9443.527985 9488.398914 9482.034418 0.93328605 0.91274233 1.020957684 1.034791871 0.923548314 0.881799822 0.919187452 0.995939011 1.000671216 1 13.21098091 AFLIEEQK ddPTM_HeLa_Curcumin_4h_R1 2 AFLIEEQK 8 0 P49207 P49207 RPL34 60S ribosomal protein L34 0 0 ; ; 116.73 0.0030803 14430400 13577.7 12035.8 12799.9 13133.3 12178.6 14582.4 12142.8 11851.2 14208.7 12530.1 FALSE FALSE TRUE 12503.01072 13076.12092 13274.27555 13078.95788 12033.37815 11557.84586 12483.49429 15464.57632 12650.04116 12965.52004 0.964327746 1.008530385 1.023813585 1.008749193 0.928106093 0.891429409 0.96282249 1.19274632 0.975667857 1 13.66239245 -4.258939401 24.85339904 0.978148024 1.192746403 0.742932799 0.038572931 89.69993487 891687.7565 0.005801088 0.052428447 5.51E-05 4.258939401 0.214598378 AFLKDY(ph)Y(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 AFLKDYYR 8 1 E7EVJ3;P52848 E7EVJ3 NDST1 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1;Heparan sulfate N-deacetylase 1;Heparan sulfate N-sulfotransferase 1 2 0 AFLKDY(1)Y(1)R 68.787 0.016548 2444100 1497.6 1421.8 1487.3 1703 1677.5 2362.5 1643.3 994.71 2100.6 1318 TRUE FALSE FALSE 1379.06338 1544.694057 1542.420646 1695.953437 1657.496908 1872.490869 1689.406575 1297.9925 1870.169435 1363.800402 1.011191504 1.132639391 1.130972424 1.243549595 1.215351532 1.372994807 1.23874914 0.951746677 1.371292627 1 10.4134168 -6.961524576 1.423355249 1.002629633 1.214110966 0 0.153413329 0.250524127 1.000874094 0.018012911 0.024284239 1.09E-07 6.961524576 0.211481333 AFNQGK(ac)IFK ddPTM_HeLa_Curcumin_4h_R1 2 AFNQGKIFK 9 1 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 1 ; AFNQGK(1)IFK;AFNQGK(1)IFK 166.68 1.26E-11 42757000 8436.5 3752.8 8554.9 5500.6 8543.2 9065.3 7718.2 8907.5 5492.4 5662.7 FALSE TRUE FALSE 7768.742123 4077.17531 8871.95212 5477.839975 8441.32792 7185.054593 7934.75192 11623.35574 4889.897461 5859.478404 1.325841924 0.69582564 1.514119775 0.934868191 1.440627875 1.226227677 1.354173763 1.983684373 0.834527773 1 12.51655653 -1.065891185 0.811960507 1.142827076 199.9999985 0.530786607 0.246927886 255.3312445 0.896502054 0.034524714 93409.27224 0.085922878 1.065891185 198.8571715 AFNWSSALTYKR ddPTM_HeLa_Curcumin_4h_R1 1 AFNWSSALTYKR 12 1 P0DKX0 P0DKX0 ZNF728 Zinc finger protein 728 0 0 32.254 0.019026 7340400 10883 5578.1 11828 8024.8 11688 10961 11275 12146 6070.2 6115.2 FALSE FALSE TRUE 10021.59907 6060.246108 12266.35608 7991.595504 11548.62823 8687.565044 11591.34615 15849.25949 5404.314247 6327.702745 1.583765779 0.957732427 1.938516485 1.262953686 1.825090195 1.372941397 1.831841131 2.504741472 0.85407208 1 12.62746611 -1 0.235041724 1.160283765 7.29407148 0.572421885 0.324090335 29.21150795 0.357941431 0.197170807 70.17198785 0.1 1 6.133787715 AFQLEEGEET(ph)EPDCK ddPTM_HeLa_Curcumin_4h_R1 3 AFQLEEGEETEPDCK 15 0 P38432 P38432 COIL Coilin 1 0 AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK;AFQLEEGEET(1)EPDCK ;; 211.17 1.12E-09 161861900 6154.6 5469.2 7452.7 7755.1 7701.2 9511.7 9069.4 2405.52 6681.3 6703.8 TRUE FALSE FALSE 5667.456916 5941.933278 7728.903618 7723.011451 7609.36822 7538.866201 9323.862955 3138.951974 5948.378106 6936.756551 0.817018281 0.856586682 1.114195599 1.113346186 1.096963424 1.086799882 1.344124287 0.452510039 0.857515766 1 12.76004554 -6.76291164 24.99896094 0.906902225 1.057502368 0.094412842 0.218776838 68.84843715 1169054.107 0.03277719 0.044391044 1.73E-07 6.76291164 0.150600143 AFRLHS(ph)S(ph)LIQHQR ddPTM_HeLa_Curcumin_4h_R1 2 AFRLHSSLIQHQR 13 1 Q9Y2G7 Q9Y2G7 ZFP30 Zinc finger protein 30 homolog 2 0 AFRLHS(1)S(1)LIQHQR;AFRLHS(1)S(1)LIQHQR ; 89.232 0.009612 43455000 56000 45686 42721 46075 48096 69919 43415 40789 52582 46065 TRUE FALSE FALSE 51567.54091 49634.89427 44304.27784 45884.35386 47522.48661 55417.01125 44633.10805 53225.37833 46813.88615 47665.75532 1.081857207 1.041311397 0.929478145 0.962627227 0.996994305 1.16261687 0.936376813 1.116637678 0.982128277 1 15.54066554 -3.886104846 15.60200419 1.027543089 6.448513921 0.137067826 0.068761154 1670345.817 2092719.198 2.93202671 317024074.8 0.000129986 3.886104846 5.420970832 AFS(ph)DPFVEAEK ddPTM_HeLa_Curcumin_4h_R1 2 AFSDPFVEAEK 11 0 P34932;A0A087WYC1;A0A087WTS8;P34932-2 P34932 HSPA4 Heat shock 70 kDa protein 4 1 0 AFS(1)DPFVEAEK;AFS(1)DPFVEAEK ; 148.13 0.0007746 23921200 9521.5 8455.6 8508.9 8601.3 9622.3 10954.7 9127.1 9079.5 10034.6 7897 TRUE FALSE FALSE 8767.863228 9186.464387 8824.247319 8565.7101 9507.560357 8682.571735 9383.181862 11847.79775 8933.829485 8171.420162 1.072991359 1.124218827 1.079891518 1.048252315 1.163513828 1.062553579 1.148292668 1.449906812 1.093301936 1 12.99637112 -1.000009115 0.896928989 1.050650335 195.2651235 0.834322722 0.047944667 244.1476053 0.516434489 0.008235774 97077.66005 0.099997901 1.000009115 194.2144731 AFS(ph)SPQEEEEAGFTGR ddPTM_HeLa_Curcumin_4h_R1 1 AFSSPQEEEEAGFTGR 16 0 A0A024RAC6;Q14241 A0A024RAC6 TCEB3 Transcription elongation factor B polypeptide 3 1 0 AFS(0.992)S(0.008)PQEEEEAGFTGR 246.75 1.42E-30 22363000 1727.1 1184.6 1146.6 1669.3 1695.6 2582 2790.8 1830.1 1998.9 1580.4 TRUE FALSE FALSE 1590.398213 1286.991546 1189.094005 1662.392879 1675.381077 2046.464095 2869.102337 2388.089065 1779.625671 1635.318782 0.972531001 0.786997348 0.727132849 1.016555852 1.024498156 1.251416003 1.754460579 1.460320209 1.088243889 1 10.67535618 -5.042541772 2.528553576 0.954098196 1.608671225 0.810713399 0.127324325 0.08410045 1.050710839 0.017757267 0.060670853 9.07E-06 5.042541772 0.65457303 AFSDPFVEAEK ddPTM_HeLa_Curcumin_4h_R1 1 AFSDPFVEAEK 11 0 P34932;A0A087WYC1;A0A087WTS8;P34932-2 P34932 HSPA4 Heat shock 70 kDa protein 4 0 0 143.89 2.05E-05 1437900 1740.7 1623.9 1981.3 1448.2 1473.1 2188.4 1413.5 1729.2 1765.8 1608.4 FALSE FALSE TRUE 1602.921758 1764.26268 2054.728721 1442.207732 1455.534245 1734.501172 1453.159006 2256.42512 1572.096158 1664.29178 0.963125443 1.060068133 1.234596448 0.866559427 0.874566745 1.042185747 0.873139568 1.355786976 0.944603691 1 10.70069267 -4.250156644 24.81012084 0.987793045 1.355787216 0.524744892 0.106009535 914.9154461 2011807.933 0.013958539 0.286607839 5.62E-05 4.250156644 0.36799417 AFSS(ph)PQEEEEAGFTGR ddPTM_HeLa_Curcumin_4h_R1 1 AFSSPQEEEEAGFTGR 16 0 A0A024RAC6;Q14241 A0A024RAC6 TCEB3 Transcription elongation factor B polypeptide 3 1 0 AFS(0.152)S(0.848)PQEEEEAGFTGR 179.55 1.71E-05 25941000 2077.5 1763.6 1939.2 2201.2 1791.9 3330.3 2685.7 2463.3 2292.7 2032.7 TRUE FALSE FALSE 1913.063683 1916.037726 2011.068458 2192.092018 1770.532763 2639.55824 2761.053514 3214.34883 2041.196546 2103.336174 0.909537765 0.91095173 0.956132682 1.04219765 0.841773552 1.254938831 1.312701958 1.528214496 0.970456635 1 11.03846374 -4.893594636 1.731750903 0.951947876 1.483820541 0.877963671 0.072832711 0.092610051 0.505967459 0.010173603 0.054197117 1.28E-05 4.893594636 0.531872665 AFT(ph)PARVS(ph)CSPHS(ph)AK ddPTM_HeLa_Curcumin_4h_R1 1 AFTPARVSCSPHSAK 15 1 H0YHN4;F8VUX9;Q96KV7 H0YHN4 WDR90 WD repeat-containing protein 90 3 0 AFT(1)PARVS(0.988)CS(0.113)PHS(0.899)AK 71.263 0.008336 0 719.76 707.57 794.08 657.75 716.5 1266.7 1177.3 691.74 1026.2 672.55 TRUE FALSE FALSE 662.7902365 768.7291979 823.5093033 655.0284048 707.9562055 1003.972141 1210.331869 902.6483416 913.6284274 695.9210624 0.952392839 1.104621256 1.183337231 0.941239517 1.017293834 1.442652329 1.739179822 1.297055644 1.312833419 1 9.442779862 -5.223145961 4.171615432 1.00114374 1.531398793 0.576759461 0.157050198 0.068164868 2.669094737 0.016479703 0.043060968 5.98E-06 5.223145961 0.530255053 AFT(ph)WSS(ph)T(ph)LT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 AFTWSSTLTK 10 0 Q8IYX0 Q8IYX0 ZNF679 Zinc finger protein 679 4 0 AFT(0.703)WS(0.329)S(0.995)T(0.978)LT(0.995)K 51.727 0.0091192 0 1150.4 719.31 866.81 1210.5 864.53 1173.4 754.79 691.33 1324.7 1053.3 TRUE FALSE FALSE 1059.344626 781.4839512 898.9347411 1205.491272 854.2210444 930.0236131 775.967376 902.1133345 1179.383724 1089.902097 0.971963105 0.717022156 0.824784854 1.106054641 0.783759429 0.853309316 0.711960623 0.827701256 1.082100611 1 10.08998283 -4.725333775 0.166261236 1.057462252 0.561210043 0.345138015 0.109990968 14.5118819 0.505522979 0.270829254 1.613294054 1.88E-05 4.725333775 -0.496252209 AFTTTLNLLPYHK ddPTM_HeLa_Curcumin_4h_R1 1 AFTTTLNLLPYHK 13 0 O43847;O43847-2;H0Y5G9;G3V1R5 O43847 NRD1 Nardilysin 0 0 78.324 0.011827 434650 314 64.832 209.06 300.32 230.74 775.87 451.6 486.68 274.92 459.8 FALSE FALSE TRUE 289.1465687 70.43578919 216.8079475 299.0773554 227.9885762 614.9458161 464.2706806 635.0664916 244.7619638 475.7780158 0.607734193 0.148043388 0.455691395 0.628606925 0.479191069 1.29250574 0.975813647 1.334795788 0.51444572 1 8.894144801 -5.253615865 24.67124254 0.698195297 1.178515941 0.540568396 0.250163796 439.7551499 1386750.483 0.042826336 0.106972113 5.58E-06 5.253615865 0.480320644 AFVDFLSDEIKEER ddPTM_HeLa_Curcumin_4h_R1 1 AFVDFLSDEIKEER 14 1 Q07021 Q07021 C1QBP "Complement component 1 Q subcomponent-binding protein, mitochondrial" 0 0 148.62 0.0004725 49182000 1987.7 1975.1 2217.2 2324.9 2695.8 3320.8 2546.8 2353.6 2548.5 1638 FALSE FALSE TRUE 1830.371448 2145.818843 2299.371382 2315.28018 2663.654346 2632.028647 2618.256354 3071.201805 2268.935926 1694.920378 1.079915889 1.26602929 1.356625014 1.366011177 1.571551313 1.552892207 1.544766579 1.812003587 1.338668149 1 10.72700179 -6.17435886 0.459286083 0.994163743 1.761175096 0.70726707 0.12449588 0.197427226 0.076352848 0.019801353 0.064062378 6.69E-07 6.17435886 0.767011353 AFVEDS(ph)EDEDGAGEGGSSLLQK ddPTM_HeLa_Curcumin_4h_R1 3 AFVEDSEDEDGAGEGGSSLLQK 22 0 H0YFD2;F8WFC1;A0A494C108;Q8N9T8 H0YFD2 KRI1 Protein KRI1 homolog 1 0 AFVEDS(1)EDEDGAGEGGSSLLQK;AFVEDS(1)EDEDGAGEGGSSLLQK;AFVEDS(1)EDEDGAGEGGSSLLQK ;; 178.76 2.78E-10 79925000 20071.9 16934.1 17298.3 18914.4 17938.1 21832.3 16906.5 10020.3 20853.2 17051.5 TRUE FALSE FALSE 18483.18794 18397.80815 17939.39022 18836.13722 17724.19987 17304.03488 17380.85089 13075.44334 18565.65613 17644.03836 1.04755995 1.042720934 1.01673947 1.067563833 1.004543264 0.980729838 0.98508349 0.741068631 1.052233948 1 14.10689318 -3.685330865 1.322523226 1.025487865 4.98E-19 0.921396113 0.024909668 1.060804275 0.546966355 0.003842541 2.134061652 0.000206381 3.685330865 -1.025487865 AFVHWYVGEGMEEGEFSEAR ddPTM_HeLa_Curcumin_4h_R1 6 AFVHWYVGEGMEEGEFSEAR 20 0 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;Q9NY65-2;Q9NY65;C9J2C0;P68363;P68363-2;P68366-2;P68366 Q9BQE3;P68363;P68366-2 TUBA1C;TUBA8;TUBA1B;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 0 ;;;;; ;;;;; 148.97 3.61E-05 48230800 8453.35 8339.6 7756.32 7253.86 8454.62 10167.16 8173.18 9064.58 8488.01 7751.05 FALSE FALSE TRUE 7784.258428 9060.437863 8043.776042 7223.845449 8353.804178 8058.376408 8402.497434 11828.32871 7556.896539 8020.398411 0.970557574 1.129674288 1.002914772 0.900684116 1.041569726 1.004735176 1.047640903 1.474780691 0.94220962 1 12.96945819 -4.250607435 3.346711925 0.996494768 1.544681545 0.859991556 0.057217586 0.082367449 1.479048707 0.007480244 0.116983439 5.62E-05 4.250607435 0.548186776 AGAAAGDS(ph)DEESRADDK ddPTM_HeLa_Curcumin_4h_R1 4 AGAAAGDSDEESRADDK 17 1 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 0 AGAAAGDS(1)DEESRADDK;AGAAAGDS(0.996)DEES(0.004)RADDK;AGAAAGDS(1)DEESRADDK;AGAAAGDS(0.982)DEES(0.018)RADDK ;;; 170.47 9.22E-14 40914000 6875.4 4976.99 6485.14 6722.62 8103 6898.51 6584.8 5675.46 6754.68 5188.22 TRUE FALSE FALSE 6331.204835 5407.178839 6725.484993 6694.80358 8006.377017 5467.681264 6769.551766 7405.881627 6013.708503 5368.510259 1.179322481 1.007202851 1.252765603 1.247050533 1.491359173 1.018472723 1.260973983 1.379504047 1.12018199 1 12.39030609 -13.52287874 0.07114255 0.113711348 1.548565121 0.275334236 0.132580872 171.0327493 0.943974494 24.79644185 3.465187062 3.00E-14 13.52287874 1.434853773 AGAAAGDS(ph)DEESRADDKGVMDYYLK ddPTM_HeLa_Curcumin_4h_R1 1 AGAAAGDSDEESRADDKGVMDYYLK 25 2 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 0 AGAAAGDS(0.751)DEES(0.232)RADDKGVMDY(0.008)Y(0.009)LK 54.66 0.0030901 57847000 2575.5 1300.6 1745.9 2151.9 2090.2 2434.2 1653.4 1492.9 2032.5 1565.8 TRUE FALSE FALSE 2371.646457 1413.018069 1810.60459 2142.996008 2065.27573 1929.319481 1699.789954 1948.078338 1809.539835 1620.211433 1.463788249 0.872119551 1.117511303 1.322664415 1.274695196 1.190782537 1.049116133 1.202360567 1.116854133 1 10.66196638 -4.965919191 23.10881424 1.201609893 1.124290824 0 0.162464093 312.0147252 211556.6278 0.028197243 0.084590577 1.08E-05 4.965919191 -0.077319069 AGAAGGPEEEAEKPVK ddPTM_HeLa_Curcumin_4h_R1 1 AGAAGGPEEEAEKPVK 16 1 Q8WW12;Q8WW12-2 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 0 0 162.67 0.00054138 1987300 1281 919.68 1175.9 1142.4 1236.5 1450.1 907.86 1217.8 1301.5 904.15 FALSE FALSE TRUE 1179.607498 999.1730412 1219.479888 1137.673051 1221.755545 1149.332914 933.3321082 1589.101614 1158.728706 935.5691452 1.260844807 1.067984174 1.303463132 1.216022415 1.305895509 1.22848527 0.997608903 1.698539998 1.238528132 1 9.869700473 -13.52287875 0.153968228 0.059218635 1.33812349 0.080337301 0.183223167 65.10326573 0.677652031 18.60335899 0.340215613 3.00E-14 13.52287875 1.278904855 RNS(ph)TTFPSR ddPTM_HeLa_Curcumin_4h_R1 1 RNSTTFPSR 9 1 Q96E09 Q96E09 FAM122A Protein FAM122A 1 0 RNS(1)TTFPSR 132.56 0.0016478 8004600 918.4 705.97 723.39 835.36 818.93 830.92 1580.9 1365.3 830.11 587.93 TRUE FALSE FALSE 845.7076709 766.9909011 750.1994698 831.9035017 809.1647946 658.5778256 1625.255799 1781.573685 739.0490098 608.3605237 1.390142256 1.260750609 1.23314949 1.367451485 1.330074459 1.0825453 2.67153396 2.928483383 1.214820786 1 9.24878273 -4.728030929 5.92226721 1.214225542 2.836377591 0.961067119 0.126075489 0.028807538 2.743473227 0.023277285 0.086644663 1.87E-05 4.728030929 1.622152048 up AGAASPLNSPLSSAVPS(ph)LGKEPFPPSSPLQK ddPTM_HeLa_Curcumin_4h_R1 1 AGAASPLNSPLSSAVPSLGKEPFPPSSPLQK 31 1 E7EPJ7;O75962-5;O75962-4;O75962 E7EPJ7 TRIO Triple functional domain protein 1 0 AGAAS(0.041)PLNS(0.046)PLS(0.046)S(0.046)AVPS(0.771)LGKEPFPPS(0.023)S(0.026)PLQK 49.888 0.0056256 22180000 1734.8 1245.9 1230.3 1492.8 1330.8 1353 630.99 869.91 1633.7 1438.4 TRUE FALSE FALSE 1597.488749 1353.590044 1275.896 1486.623189 1314.931079 1072.372549 648.6938812 1135.141554 1454.487197 1488.384293 1.073303956 0.909435857 0.857235599 0.998816768 0.883462077 0.7204944 0.435837629 0.76266698 0.977225576 1 10.53953136 -5.31679203 1.845131123 1.009268179 0.592940436 0.687510631 0.098411934 0.129572793 0.84273907 0.014735337 0.046004388 4.82E-06 5.31679203 -0.416327742 AGAASPLNSPLSSAVPSLGKEPFPPSS(ph)PLQK ddPTM_HeLa_Curcumin_4h_R1 2 AGAASPLNSPLSSAVPSLGKEPFPPSSPLQK 31 1 E7EPJ7;O75962-5;O75962-4;O75962 E7EPJ7 TRIO Triple functional domain protein 1 0 AGAASPLNSPLSSAVPSLGKEPFPPS(0.382)S(0.618)PLQK;AGAASPLNSPLSSAVPSLGKEPFPPS(0.363)S(0.637)PLQK ; 91.432 2.71E-08 69751000 4493.5 3477.91 4106.2 4055.6 4717.9 6949.8 5408.8 1313.16 5561.6 4790.9 TRUE FALSE FALSE 4137.834733 3778.525043 4258.379384 4038.819002 4661.642124 5508.33314 5560.556371 1713.536439 4951.506394 4957.383418 0.834681199 0.762201493 0.858997383 0.814707813 0.940343268 1.111137202 1.121671636 0.345653401 0.998814491 1 12.27536313 -9.297678659 1.070201966 0.998545465 0.864667346 0.075546152 0.203992324 1.279648192 2.667581637 0.125182665 0.035034038 5.04E-10 9.297678659 -0.133878119 AGADEERAETAR ddPTM_HeLa_Curcumin_4h_R1 2 AGADEERAETAR 12 1 F5GWF6;P78371;F8VQ14 F5GWF6 CCT2 T-complex protein 1 subunit beta 0 0 ; ; 94.363 0.0074046 1865200 3052.9 2045.11 1791.19 2542.9 1451.67 2963.7 1847.32 1814.38 4000.6 3138.5 FALSE FALSE TRUE 2811.259744 2221.880196 1857.573077 2532.378154 1434.359783 2348.995212 1899.150827 2367.57611 3561.744189 3247.562641 0.8656522 0.684168541 0.571989914 0.779778078 0.441672707 0.723310209 0.58479267 0.729031699 1.096743799 1 11.66514164 -7.443197479 1.205257581 0.960105288 0.630985293 0.698839359 0.103612672 0.156939201 0.450997733 0.018821619 0.020590348 3.60E-08 7.443197479 -0.329119995 AGAES(ph)PTMSVDGR ddPTM_HeLa_Curcumin_4h_R1 1 AGAESPTMSVDGR 13 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 0 AGAES(0.765)PT(0.235)MSVDGR 190.34 8.12E-06 66068000 2867.9 2608.2 2859.3 2594.7 2487.4 3245.4 2280.6 1384.2 3155.8 2674.4 TRUE FALSE FALSE 2640.902689 2833.641186 2965.268173 2583.963819 2457.73938 2572.267457 2344.587498 1806.236208 2809.616635 2767.335201 0.954312542 1.023960229 1.071524755 0.933737199 0.888124929 0.929510619 0.847236539 0.652698743 1.015278754 1 11.43428169 -3.567960191 0.736713923 0.985070771 7.59E-18 0.851001347 0.043518872 1.889096063 0.352773978 0.007486741 1.96157023 0.000270421 3.567960191 -0.985070771 AGAESPTMS(ph)VDGR ddPTM_HeLa_Curcumin_4h_R1 1 AGAESPTMSVDGR 13 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 0 AGAES(0.029)PT(0.013)MS(0.958)VDGR 128.21 0.0017719 68412000 3192.3 2843.8 2988.9 3491.4 3261.7 3601.2 3170.1 1671.2 3756.5 2759.4 TRUE FALSE FALSE 2939.626087 3089.6054 3099.671263 3476.953512 3222.806358 2854.270526 3259.044474 2180.741187 3344.421348 2855.288945 1.029537165 1.082064008 1.085589348 1.217723873 1.128714614 0.999643322 1.141406189 0.763754993 1.171307497 1 11.47942103 -1.754984822 14.30838374 1.038180847 0.189842392 0 0.123008421 0 0 0.014438044 0 0.017579851 1.754984822 -0.848338455 AGAGK(ac)IGR ddPTM_HeLa_Curcumin_4h_R1 1 AGAGKIGR 8 1 A0A669KBF4;O00327-4;O00327-9;O00327-1;O00327-7;O00327-8;O00327 A0A669KBF4 ARNTL Aryl hydrocarbon receptor nuclear translocator-like protein 1 0 1 AGAGK(1)IGR 97.602 0.015335 6124600 1252.4 1426.4 1088.1 1121.6 1139.7 1535.4 1464.7 1058.8 1241.3 1485.7 FALSE TRUE FALSE 1153.271218 1549.69166 1128.425943 1116.959116 1126.109822 1216.940732 1505.79554 1381.623246 1105.132496 1537.327964 0.750179041 1.008042328 0.734017704 0.726558771 0.732511115 0.791594741 0.979488811 0.898717306 0.718865799 1 10.58620926 -9.47683826 1.12033697 1.00373608 0.819851695 0 0.130875138 0.531534358 1.15344196 0.078952676 0.017803577 3.34E-10 9.47683826 -0.183884385 AGAGMITQHS(ph)SNASPINR ddPTM_HeLa_Curcumin_4h_R1 1 AGAGMITQHSSNASPINR 18 0 Q9NWH9;Q9NWH9-3;H7C3F4;H0YKH2 Q9NWH9 SLTM SAFB-like transcription modulator 1 0 AGAGMIT(0.277)QHS(0.596)S(0.123)NAS(0.004)PINR 76.118 0.0054375 4146800 1149.6 1171.7 1100.8 1079.3 1231.4 2103.3 1260.8 765.88 1467.8 1088.7 TRUE FALSE FALSE 1058.607947 1272.976527 1141.596616 1074.834143 1216.716359 1667.051871 1296.174655 999.3932863 1306.786012 1126.532244 0.939704969 1.129995643 1.01337234 0.954108636 1.080054624 1.479808394 1.150588154 0.887141306 1.160007642 1 10.13767289 -5.5199064 23.56378965 0.987692981 1.188588696 0.100994122 0.152087975 52.53646465 416488.6914 0.020129929 0.040941924 3.02E-06 5.5199064 0.200895716 AGAGPGGPPQK(ac)PAPSSQR ddPTM_HeLa_Curcumin_4h_R1 2 AGAGPGGPPQKPAPSSQR 18 1 Q9Y5J1 Q9Y5J1 UTP18 U3 small nucleolar RNA-associated protein 18 homolog 0 1 ; AGAGPGGPPQK(1)PAPSSQR;AGAGPGGPPQK(1)PAPSSQR 160.46 0.001208 2299900 181.57 260.055 441.23 356.53 483.67 413.95 152.9 392.31 251.961 391.36 FALSE TRUE FALSE 167.1985429 282.5329954 457.5823719 355.0547733 477.9025511 328.0921038 157.1899625 511.923513 224.3215087 404.9597309 0.412876961 0.697681705 1.129945368 0.876765629 1.180123639 0.810184517 0.388161959 1.264134367 0.553935346 1 8.661634644 -6.827218023 24.99990789 0.713120344 0.918329416 0.189850502 0.269336878 108.556575 41257.05229 0.049823229 0.065480564 1.49E-07 6.827218023 0.205209073 AGAHLQGGAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 AGAHLQGGAKR 11 1 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 1 ; AGAHLQGGAK(1)R;AGAHLQGGAK(1)R 105.98 0.0012675 5061200 2185.64 1900.16 2015.88 1572.18 2420.8 3109.1 2301.3 2537.7 2328.4 1893.77 FALSE TRUE FALSE 2012.644288 2064.401363 2090.590286 1565.674736 2391.933541 2464.237613 2365.868284 3311.433048 2072.980345 1959.578367 1.027080275 1.053492628 1.066857198 0.798985518 1.220636838 1.257534608 1.207335376 1.68987018 1.057870602 1 10.93632755 -1 0.615628603 1.009856103 47.4741886 0.782952945 0.103692952 51.46180175 0.347908915 0.016855036 3239.670949 0.1 1 46.4643325 AGAISASGPELQGAGHSK ddPTM_HeLa_Curcumin_4h_R1 2 AGAISASGPELQGAGHSK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 176.28 3.97E-06 6936000 2552 2459.8 2568.4 2382.7 2860.8 3860.2 2334.5 2160.7 2731.5 2358 FALSE FALSE TRUE 2350.006507 2672.414151 2663.587163 2372.841019 2826.686828 3059.551007 2399.999787 2819.487483 2431.861284 2439.940324 0.963140977 1.095278489 1.091660782 0.972499612 1.158506542 1.253945015 0.983630527 1.155555919 0.996688837 1 11.25263015 -6.688538768 0.879628758 0.982500608 1.121450433 0.292451906 0.079208368 0.454538222 0.703670459 0.016001985 0.026824975 2.05E-07 6.688538768 0.138949825 AGAPGALS(ph)PSYDGGLHGLQSK ddPTM_HeLa_Curcumin_4h_R1 3 AGAPGALSPSYDGGLHGLQSK 21 0 K7ENH8;A0A0A0MRB7;P15923-2;X6REB3;P15923;P15923-3 K7ENH8 TCF3 Transcription factor E2-alpha 1 0 AGAPGALS(0.999)PS(0.001)YDGGLHGLQSK;AGAPGALS(0.992)PS(0.008)YDGGLHGLQSK;AGAPGALS(0.986)PS(0.014)YDGGLHGLQSK ;; 140.93 7.39E-06 132812000 11097 7887.8 8435.4 8884.5 10415.1 12998 6328 7494.6 10818.3 8167.8 TRUE FALSE FALSE 10218.66074 8569.586285 8748.023345 8847.738293 10290.90673 10302.06828 6505.546649 9779.669039 9631.559556 8451.630442 1.20907567 1.013956578 1.035069316 1.046867626 1.217623843 1.218944481 0.769738655 1.157134012 1.139609644 1 13.04501397 -4.783009118 24.99999494 1.101326143 0.963435918 0.193732139 0.118629111 273.6798766 317203.9667 0.017126199 0.051444516 1.65E-05 4.783009118 -0.137890224 AGAPS(ph)SERT(ph)AS(ph)RVR ddPTM_HeLa_Curcumin_4h_R1 1 AGAPSSERTASRVR 14 2 Q9H7P9-3;Q9H7P9;H7BXC7;E7ESZ3;M0R3J0 Q9H7P9-3 PLEKHG2 Pleckstrin homology domain-containing family G member 2 3 0 AGAPS(0.894)S(0.558)ERT(0.897)AS(0.651)RVR 83.862 0.015648 34472000 483.92 484.85 770.91 695.2 643.58 966.35 441.22 643.69 750.24 506.03 TRUE FALSE FALSE 445.6172214 526.7582736 799.4806028 692.3234466 635.9057288 765.918117 453.5994457 839.9481178 667.940549 523.6145048 0.851040636 1.006003976 1.526849611 1.322200665 1.214453998 1.46275191 0.866285104 1.604134549 1.27563416 1 9.032361252 -6.910103666 6.937754607 0.929629138 1.310722239 0.261698959 0.222269765 0.135770706 8.903714131 0.029035413 0.038244455 1.23E-07 6.910103666 0.381093101 AGAPVGGS(ph)PGLAK ddPTM_HeLa_Curcumin_4h_R1 2 AGAPVGGSPGLAK 13 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 0 AGAPVGGS(1)PGLAK;AGAPVGGS(1)PGLAK ; 144.51 0.00079495 68602000 10360.2 8575.6 10121.4 9978.3 10445.6 11820.3 9584 3720.5 10669.6 9163.4 TRUE FALSE FALSE 9540.179238 9316.836652 10496.50799 9937.012439 10321.04304 9368.636538 9852.901246 4854.863323 9499.171574 9481.827468 1.006154064 0.98259926 1.107013181 1.048006038 1.088507788 0.98806233 1.039135259 0.512017682 1.001829194 1 13.21094943 -4.259992856 24.99498841 1.018082226 0.512017516 0.933355378 0.0413531 22.88855347 395459.1875 0.005907315 0.049687557 5.50E-05 4.259992856 -0.506064709 AGASIPSSGAAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 AGASIPSSGAASPR 14 0 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 0 AGASIPSSGAAS(1)PR;AGASIPSSGAAS(1)PR ; 209.19 2.09E-09 256345000 7551.2 5640.3 5436.1 6240 5912.5 8442.1 6018.6 3015 7617.5 5022.8 TRUE FALSE FALSE 6953.514552 6127.822399 5637.566648 6214.180533 5841.997299 6691.113298 6187.465718 3934.259621 6781.879308 5197.341926 1.337898228 1.179030067 1.084701897 1.195645894 1.12403559 1.28741064 1.190505802 0.75697533 1.304874569 1 12.34355826 -4.259561093 24.21786845 1.168949702 0.756975109 0.621959064 0.099995056 71.99612036 928169.1705 0.017598779 0.152185269 5.50E-05 4.259561093 -0.411974593 AGDEKPEK(ac)SQR ddPTM_HeLa_Curcumin_4h_R1 2 AGDEKPEKSQR 11 2 Q8WW12;Q8WW12-2;G5E9V9;A0A0B4J1Z9 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 0 1 ; AGDEK(0.001)PEK(0.999)SQR;AGDEK(0.029)PEK(0.971)SQR 89.171 0.0054378 5402800 5513.2 4623.2 4423.4 4169.8 4754.6 6608.1 4474.4 5617 5111.9 4346.5 FALSE TRUE FALSE 5076.824402 5022.808807 4587.335095 4152.546472 4697.9045 5237.505571 4599.939622 7329.597443 4551.137359 4497.540551 1.12880014 1.11679011 1.019965255 0.923292725 1.04454967 1.164526592 1.022767793 1.629690129 1.011916915 1 12.13492057 -4.259311023 24.96965837 1.057720051 1.629690329 0.86775736 0.068022114 53.71639232 630149.21 0.010351389 0.091686586 5.50E-05 4.259311023 0.571970278 AGDFGAAFVERY(ph)MR ddPTM_HeLa_Curcumin_4h_R1 1 AGDFGAAFVERYMR 14 1 O14841 O14841 OPLAH 5-oxoprolinase 1 0 AGDFGAAFVERY(1)MR 75.387 0.0087233 0 702.95 861.92 757.33 999.88 921.6 818.28 717.22 632.62 1001 882.98 TRUE FALSE FALSE 647.3107658 936.4205242 785.397316 995.7427615 910.6105219 648.5595041 737.3432629 825.5029258 891.1928044 913.6634893 0.708478311 1.024907458 0.859613332 1.089835342 0.996658543 0.709845049 0.807018417 0.903508716 0.975405951 1 9.835519095 -5.260372143 24.99768457 0.896923263 0.806813503 0.145997469 0.116611717 210.0530659 4919933.25 0.020353767 0.04883826 5.49E-06 5.260372143 -0.09010976 PLRAPS(ph)PEPAAPR ddPTM_HeLa_Curcumin_4h_R1 1 PLRAPSPEPAAPR 13 1 P20749 P20749 BCL3 B-cell lymphoma 3 protein 1 0 PLRAPS(1)PEPAAPR 93.716 0.0044872 6769300 3009.7 3341.8 2098.6 4231.8 2323.6 551.79 1031.6 790.91 3390.2 3599.5 TRUE FALSE FALSE 2771.479069 3630.650301 2176.375962 4214.289933 2295.892588 437.342534 1060.54392 1032.054818 3018.303542 3724.582357 0.744104655 0.974780513 0.584327517 1.131479862 0.616416115 0.117420557 0.284741702 0.277092763 0.810373688 1 11.86286295 -5.466504283 4.393043276 0.876145539 0.239593795 0.792271998 0.14809218 0.072176455 2.854029111 0.021674064 0.049001943 3.42E-06 5.466504283 -0.636551744 down AGDLLEDS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 8 AGDLLEDSPK 10 0 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 0 AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK;AGDLLEDS(1)PK ;;;;;;; 134.99 0.0022139 4767175100 46919.8 48289.8 52678.4 49328 54861.6 45163.2 45977.4 46962.8 45772.2 43681.7 TRUE FALSE FALSE 43206.04832 52463.75514 54630.70784 49123.89381 54207.41125 35795.84323 47267.4021 61281.54153 40751.10418 45199.63582 0.955893726 1.160711899 1.208653717 1.086820566 1.199288673 0.791949815 1.04574741 1.355797241 0.901580365 1 15.46402353 -7.268682095 24.66605388 0.979172035 1.110744929 0.227380624 0.139067248 622.0360193 2118424.508 0.023088333 0.026697544 5.39E-08 7.268682095 0.131572894 AGDLLEDS(ph)PKRPK ddPTM_HeLa_Curcumin_4h_R1 1 AGDLLEDSPKRPK 13 2 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 0 AGDLLEDS(1)PKRPK 194.77 7.91E-05 340830000 2397.2 2211.4 1951.9 2362.2 2297 2607.6 2254.4 2114.5 2426.9 2424.7 TRUE FALSE FALSE 2207.45909 2402.543562 2024.239131 2352.425842 2269.609775 2066.754366 2317.652397 2759.201316 2160.675142 2508.958145 0.879830975 0.957586147 0.806804663 0.937610636 0.904602486 0.823750038 0.923750921 1.099739875 0.861184212 1 11.29287269 -9.415242894 1.088156992 1.00109813 0.90910553 0 0.087463823 0.75362801 1.565182375 0.053808887 0.012955409 3.84E-10 9.415242894 -0.0919926 AGDLRYPTHFLSTNSVLAS(ph)VTASLK ddPTM_HeLa_Curcumin_4h_R1 1 AGDLRYPTHFLSTNSVLASVTASLK 25 1 A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-1 A0A3B3IPE9 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 0 AGDLRY(0.001)PT(0.001)HFLS(0.006)T(0.03)NS(0.05)VLAS(0.663)VT(0.192)AS(0.058)LK 45.125 0.014944 11975000 1272.9 1457.5 1019.1 2552.3 1486.4 2214.7 1104 538.36 2677.4 1680.8 TRUE FALSE FALSE 1172.148622 1583.479806 1056.868742 2541.739259 1468.675651 1755.346255 1134.975269 702.5034857 2383.695919 1739.207675 0.673955525 0.910460452 0.607672538 1.461435167 0.844450995 1.009279272 0.652581796 0.403921565 1.370564282 1 10.7642145 -4.496507502 3.516939903 0.882903508 0.424975423 0.276432685 0.269691468 0.224496944 5.463112973 0.031668083 0.196323265 3.19E-05 4.496507502 -0.457928085 AGDPGEMPQS(ph)PTGLGQPK ddPTM_HeLa_Curcumin_4h_R1 5 AGDPGEMPQSPTGLGQPK 18 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9;H0YHL2 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 0 AGDPGEMPQS(0.878)PT(0.122)GLGQPK;AGDPGEMPQS(0.999)PT(0.001)GLGQPK;AGDPGEMPQS(0.858)PT(0.142)GLGQPK;AGDPGEMPQS(0.654)PT(0.346)GLGQPK;AGDPGEMPQS(0.98)PT(0.02)GLGQPK ;;;; 211.16 8.34E-13 81485600 15489.2 13757.34 16282.5 16282.3 16539.9 17481.2 14128.3 10494.78 17327.9 14664.3 TRUE FALSE FALSE 14263.21348 14946.46317 16885.94377 16214.92816 16342.6725 13855.40207 14524.70207 13694.59011 15427.07272 15173.88333 0.93998439 0.985012395 1.112829419 1.068607673 1.077026371 0.913108514 0.957217197 0.902510571 1.016685866 1 13.88930273 -5.194311988 24.999947 0.996473369 0.927572494 0.336957483 0.055398879 248.3178934 92478.9094 0.009334372 0.023798111 6.39E-06 5.194311988 -0.068900874 AGDRNS(ph)EDDGVVMTFSSVK ddPTM_HeLa_Curcumin_4h_R1 1 AGDRNSEDDGVVMTFSSVK 19 1 Q9NY61 Q9NY61 AATF Protein AATF 1 0 AGDRNS(1)EDDGVVMTFSSVK 91.378 0.0041091 8828000 2243.4 2253.7 2194.1 2078.1 2601.9 2810.7 1939.6 1796.2 1782.7 1194.5 TRUE FALSE FALSE 2065.832523 2448.499786 2275.415276 2069.501373 2570.874042 2227.729137 1994.019956 2343.853111 1587.14227 1236.008786 1.671373655 1.9809728 1.840937784 1.674341959 2.079980394 1.80235704 1.613273286 1.896307808 1.28408656 1 10.27147328 -8.728162197 0.621685138 0.977599357 1.842217476 0.744235092 0.156837791 0.232990568 0.171332043 0.101791372 0.034082081 1.87E-09 8.728162197 0.864618119 AGDTS(ph)DQEGHSLEEK ddPTM_HeLa_Curcumin_4h_R1 2 AGDTSDQEGHSLEEK 15 0 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 0 AGDT(0.232)S(0.768)DQEGHSLEEK;AGDT(0.254)S(0.746)DQEGHSLEEK ; 115.56 0.00078305 112393000 13753.9 10392.1 12321.9 12333 11987.8 13356.5 10446.7 6085.9 13902.3 11247 TRUE FALSE FALSE 12665.2643 11290.34682 12778.56045 12281.96931 11844.85331 10586.21134 10739.80629 7941.462894 12377.25247 11637.83241 1.088283785 0.970141725 1.098018944 1.055348529 1.017788613 0.90963772 0.92283562 0.682383335 1.063535892 1 13.50653476 -3.62446339 0.799510842 1.042296871 5.36E-20 0.859078714 0.043942463 1.651270214 0.373245014 0.007583163 1.948001201 0.000237431 3.62446339 -1.042296871 AGEAPTENPAPPTQQS(ph)SAE ddPTM_HeLa_Curcumin_4h_R1 2 AGEAPTENPAPPTQQSSAE 19 0 P16989-2;P16989 P16989-2 YBX3 Y-box-binding protein 3 1 0 AGEAPTENPAPPT(0.002)QQS(0.499)S(0.499)AE;AGEAPTENPAPPT(0.029)QQS(0.485)S(0.485)AE ; 120.82 0.00022382 13715700 2987.03 2686.04 2596.3 2704.71 2476.01 3551.6 2260.72 3240.31 3401.31 2442.24 TRUE FALSE FALSE 2750.603424 2918.209329 2692.521162 2693.518627 2446.485198 2814.958125 2324.149719 4228.265602 3028.194803 2527.107658 1.088439353 1.154762568 1.065455662 1.065850368 0.968096943 1.113905107 0.919687656 1.673164018 1.198284843 1 11.30327141 -4.254271613 24.99989837 1.047054231 1.673164309 0.833980441 0.081250285 193.3164191 674236.6809 0.008999922 0.122012534 5.57E-05 4.254271613 0.626110078 EGLISQDGSS(ph)LEALLR ddPTM_HeLa_Curcumin_4h_R1 2 EGLISQDGSSLEALLR 16 0 J3KMZ8;Q92785;Q92785-2 J3KMZ8 DPF2 Zinc finger protein ubi-d4 1 0 EGLISQDGS(0.049)S(0.951)LEALLR;EGLISQDGS(0.01)S(0.99)LEALLR ; 237.4 1.21E-24 5224700 1903.22 1578.93 1677.9 1841.97 1816.2 1921.08 3164.2 2802.7 2301.3 1609.63 TRUE FALSE FALSE 1752.578129 1715.405674 1740.08445 1834.348416 1794.543001 1522.626353 3252.978936 3657.230328 2048.853148 1665.564523 1.052242711 1.029924479 1.044741543 1.101337349 1.077438296 0.914180347 1.953078906 2.195790243 1.230125354 1 10.70179553 -4.698426088 4.894129932 1.029965015 2.126333419 0.955087748 0.088529974 0.017350832 0.802808616 0.008298856 0.032526593 2.00E-05 4.698426088 1.096368404 up AGEK(ac)GSHEEEPVK ddPTM_HeLa_Curcumin_4h_R1 1 AGEKGSHEEEPVK 13 1 C9JQA7;C9J8X5;Q9P0W2-3;Q9P0W2 C9JQA7 HMG20B SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related 0 1 AGEK(1)GSHEEEPVK 107.93 0.0034511 1203900 1562.6 2021 2037.1 1406.5 1513.5 2658 1461.2 1567.7 1631.4 1716.5 FALSE TRUE FALSE 1438.918561 2195.686235 2112.596718 1400.680276 1495.452501 2106.700838 1502.197339 2045.684513 1452.439502 1776.148247 0.810134269 1.236206627 1.189425895 0.788605499 0.841963785 1.18610642 0.845761237 1.151753248 0.817746775 1 10.79453629 AGEK(ac)VEKPDTK ddPTM_HeLa_Curcumin_4h_R1 1 AGEKVEKPDTK 11 2 Q02878;F8VZ45;U3KQR5;F8VZA3;F8VWR1;F8VU16 Q02878 RPL6 60S ribosomal protein L6 0 1 AGEK(0.999)VEK(0.001)PDTK 103.21 0.0016195 14029000 5516 4905.2 4834 4931 4855.6 6932.3 5743.7 6071.3 5914.5 5049.2 FALSE TRUE FALSE 5079.40278 5329.183631 5013.152292 4910.596829 4797.700141 5494.462837 5904.852764 7922.411421 5265.694147 5224.659324 0.972197892 1.020005956 0.959517546 0.939888426 0.918279996 1.051640403 1.130189051 1.516349857 1.007854067 1 12.35112125 -4.135565956 1.545666218 0.980169107 1.847578799 0.958584994 0.033611328 0.202682659 0.352277454 0.004933536 0.290431132 7.32E-05 4.135565956 0.867409692 AGELADK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 AGELADKK 8 1 Q9BUQ8;F8W1J5;F8VVA2;Q9BUQ8-2 Q9BUQ8 DDX23 Probable ATP-dependent RNA helicase DDX23 0 1 AGELADK(1)K 82.426 0.012993 2708700 1954.6 2536.5 2206.9 1985.4 2257.7 2437.5 2022.2 1935.3 2148.5 1831 FALSE TRUE FALSE 1799.891348 2755.743758 2288.689655 1977.184941 2230.778402 1931.935024 2078.93749 2525.364061 1912.814925 1894.627114 0.949997672 1.45450455 1.207989498 1.04357471 1.177423455 1.019691426 1.097280554 1.332908224 1.009599679 1 10.88769822 AGELTEDEVER ddPTM_HeLa_Curcumin_4h_R1 4 AGELTEDEVER 11 0 P62269 P62269 RPS18 40S ribosomal protein S18 0 0 ;;; ;;; 197.79 3.88E-16 135611200 8730.2 7590.5 7630.6 7649.4 7912.1 10870 8048.4 7675.3 8083.8 7659.5 FALSE FALSE TRUE 8039.195458 8246.588997 7913.396749 7617.74881 7817.753375 8615.43947 8274.216443 10015.46364 7197.027365 7925.667055 1.014324145 1.040491474 0.998451827 0.961149233 0.986384278 1.087030203 1.043977294 1.263674536 0.908065821 1 12.95231665 SSS(ph)ALDSPAGPR ddPTM_HeLa_Curcumin_4h_R1 1 SSSALDSPAGPR 12 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 0 S(0.025)S(0.003)S(0.972)ALDSPAGPR 138.42 0.0013865 15461000 2486.4 2524.8 2122.6 2152.3 1880.6 1083.9 648.91 615.94 2879 2581.8 TRUE FALSE FALSE 2289.598816 2743.032462 2201.265423 2143.394353 1858.175073 859.0869219 667.1166681 803.7372706 2563.180903 2671.517358 0.857040591 1.02676947 0.823975714 0.802313467 0.69555044 0.321572652 0.249714518 0.30085422 0.959447595 1 11.38344368 -5.446469927 1.320577107 0.932328862 0.239649662 0.950811676 0.063499857 0.075457338 0.249123561 0.011223154 0.038597258 3.58E-06 5.446469927 -0.6926792 down AGEPDGES(ph)LDEQPSSSSSKR ddPTM_HeLa_Curcumin_4h_R1 1 AGEPDGESLDEQPSSSSSKR 20 1 Q9H3Q1;J3KRZ9 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 0 AGEPDGES(0.999)LDEQPSSSSSKR 67.194 0.0051634 0 1802.4 2039.9 1605.2 1686.8 1256.6 1871.4 1391.7 893.58 2113.9 1516.6 TRUE FALSE FALSE 1659.738138 2216.219866 1664.690124 1679.820469 1241.615866 1483.250545 1430.747356 1166.028428 1882.010459 1569.301737 1.057628434 1.412233106 1.060783968 1.070425418 0.791190016 0.945165936 0.911709535 0.743023729 1.199266154 1 10.61590706 -5.772465133 24.91816798 1.065430359 0.859295939 0.49511246 0.130710066 168.7309643 381331.8617 0.019471375 0.035539196 1.69E-06 5.772465133 -0.20613442 AGEPNS(ph)PDAEEANS(ph)PDVTAGCDPAGVHPPR ddPTM_HeLa_Curcumin_4h_R1 6 AGEPNSPDAEEANSPDVTAGCDPAGVHPPR 30 0 Q08J23-2;Q08J23;Q08J23-3 Q08J23-2 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 2 0 AGEPNS(1)PDAEEANS(0.999)PDVT(0.001)AGCDPAGVHPPR;AGEPNS(1)PDAEEANS(0.995)PDVT(0.005)AGCDPAGVHPPR;AGEPNS(1)PDAEEANS(1)PDVTAGCDPAGVHPPR;AGEPNS(1)PDAEEANS(0.989)PDVT(0.011)AGCDPAGVHPPR;AGEPNS(1)PDAEEANS(0.995)PDVT(0.005)AGCDPAGVHPPR;AGEPNS(0.998)PDAEEANS(0.653)PDVT(0.35)AGCDPAGVHPPR ;;;;; 147.74 2.50E-12 2388855000 8325.03 6424.84 6945.12 7181.49 6762.46 8628.2 6042.17 4990.45 8386.69 7143.96 TRUE FALSE FALSE 7666.095091 6980.174541 7202.512257 7151.774897 6681.822081 6838.61406 6211.697029 6512.015232 7466.691089 7392.212078 1.03705021 0.94426059 0.974337882 0.967474258 0.903900214 0.925110642 0.84030287 0.880929167 1.010075335 1 12.85179043 -5.742766997 0.635598181 1.016481895 0.851737839 0.796326999 0.026368868 0.299934577 0.202757607 0.005782015 0.025704159 1.81E-06 5.742766997 -0.164744056 AGEPNS(ph)PDAEEANSPDVTAGCDPAGVHPPR ddPTM_HeLa_Curcumin_4h_R1 3 AGEPNSPDAEEANSPDVTAGCDPAGVHPPR 30 0 Q08J23-2;Q08J23;Q08J23-3 Q08J23-2 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 0 AGEPNS(0.986)PDAEEANS(0.014)PDVTAGCDPAGVHPPR;AGEPNS(1)PDAEEANSPDVTAGCDPAGVHPPR;AGEPNS(0.626)PDAEEANS(0.372)PDVT(0.002)AGCDPAGVHPPR ;; 141.82 2.02E-12 3187804000 4683.5 4669.7 4354.8 4702.9 3937.3 5078.3 3827.4 3915.8 5019.3 4630.5 TRUE FALSE FALSE 4312.796033 5073.32806 4516.192719 4683.440646 3890.350269 4025.003336 3934.786543 5109.709394 4468.695348 4791.40953 0.900110084 1.058838329 0.942560366 0.977466154 0.811942758 0.840045776 0.821216913 1.066431363 0.932647339 1 12.22623441 -5.784691658 24.89390926 0.961249482 0.877155196 0.210925925 0.077960184 260.7201541 279126.7308 0.011512585 0.020877934 1.64E-06 5.784691658 -0.084094286 AGEPNSPDAEEANS(ph)PDVTAGCDPAGVHPPR ddPTM_HeLa_Curcumin_4h_R1 3 AGEPNSPDAEEANSPDVTAGCDPAGVHPPR 30 0 Q08J23-2;Q08J23;Q08J23-3 Q08J23-2 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 0 AGEPNSPDAEEANS(0.96)PDVT(0.04)AGCDPAGVHPPR;AGEPNSPDAEEANS(0.992)PDVT(0.008)AGCDPAGVHPPR;AGEPNSPDAEEANS(1)PDVTAGCDPAGVHPPR ;; 141.21 2.43E-12 87663200 2350.87 2237.8 2423.93 2259.39 2369.43 2580.09 2046.29 1957.8 3063.37 2669.05 TRUE FALSE FALSE 2164.796159 2431.225461 2513.762978 2250.041243 2341.176095 2044.95025 2103.70339 2554.724207 2727.325975 2761.799289 0.783835439 0.880304905 0.91019032 0.814701217 0.847699579 0.740441298 0.761714799 0.925021676 0.987517806 1 11.43139276 -9.405934706 0.920604832 1.009609772 0.827428308 0.548576242 0.058075562 0.405748343 0.560893826 0.05331963 0.010992186 3.93E-10 9.405934706 -0.182181464 AGFAGDDAPR ddPTM_HeLa_Curcumin_4h_R1 3 AGFAGDDAPR 10 0 P60709;A0A2R8Y793;P63267-2;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;Q6S8J3;C9JZR7;A5A3E0;C9JTX5;P0CG38;P0CG39;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG2;POTEE;POTEF;POTEI;POTEJ;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;POTE ankyrin domain family member J;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 0 0 ;; ;; 141.52 2.10E-05 1075892400 25314.3 19419.7 21214 21162.2 20798.1 25549.9 22080.2 22260 22502.2 20435.8 FALSE FALSE TRUE 23310.64644 21098.25234 22000.2095 21074.63642 20550.09624 20250.56273 22699.71099 29046.97153 20033.76496 21145.94253 1.102369706 0.997744712 1.040398624 0.996627906 0.971822193 0.957657135 1.073478326 1.373642792 0.947404682 1 14.36809325 -4.272546292 3.981069057 1.030670541 1.401287505 0.827969674 0.049289708 0.075172397 2.455961595 0.007400397 0.078840486 5.34E-05 4.272546292 0.370616964 AGFNYESPS(ph)KGGNFPSFPHDEVTDR ddPTM_HeLa_Curcumin_4h_R1 1 AGFNYESPSKGGNFPSFPHDEVTDR 25 1 Q9UHF7;Q9UHF7-3;Q9UHF7-2;H0YC29;E5RJ97 Q9UHF7 TRPS1 Zinc finger transcription factor Trps1 1 0 AGFNY(0.103)ES(0.247)PS(0.628)KGGNFPS(0.022)FPHDEVTDR 49.266 0.0094872 11190000 1366.1 971.51 1173.1 1294.6 1214.3 1714.5 1329.6 380.61 1327.5 1324.7 TRUE FALSE FALSE 1257.971743 1055.482995 1216.576118 1289.243288 1199.820266 1358.893374 1366.904998 496.6562369 1181.876571 1370.733226 0.917736376 0.770013432 0.887536754 0.940550111 0.875312747 0.991362395 0.997207167 0.362328882 0.862222166 1 10.4207321 -4.257950288 24.97366854 0.939499637 0.362328661 0.839662873 0.071883543 94.86864934 679004.5532 0.010438522 0.102162679 5.52E-05 4.257950288 -0.577170976 AGFSPDS(ph)SKADSDAASSGGSDSK ddPTM_HeLa_Curcumin_4h_R1 1 AGFSPDSSKADSDAASSGGSDSK 23 1 O95402;B8ZZF3 O95402 MED26 Mediator of RNA polymerase II transcription subunit 26 1 0 AGFS(0.045)PDS(0.475)S(0.475)KADS(0.005)DAASSGGSDSK 78.057 0.00028538 11809000 2530.8 1905.8 2687.5 2196.5 2449.5 2881.5 2074.3 2499.1 2962.3 2675.6 TRUE FALSE FALSE 2330.48451 2070.52886 2787.101114 2187.411465 2420.291312 2283.844419 2132.499275 3261.064086 2637.343101 2768.576901 0.841762607 0.747867563 1.006690879 0.790085139 0.8742005 0.824916374 0.770251054 1.177884596 0.952598825 1 11.43492888 -9.293767026 1.045071556 0.999244017 0.869394087 0.083223 0.122283075 0.779391266 1.538628523 0.073259827 0.02014651 5.08E-10 9.293767026 -0.12984993 AGGAGVPAFYTPTGYGTLVQEGGS(ph)PIKYNK ddPTM_HeLa_Curcumin_4h_R1 2 AGGAGVPAFYTPTGYGTLVQEGGSPIKYNK 30 1 P55809 P55809 OXCT1 "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial" 1 0 AGGAGVPAFY(0.001)T(0.003)PT(0.036)GY(0.104)GT(0.104)LVQEGGS(0.752)PIKYNK;AGGAGVPAFYT(0.001)PT(0.008)GY(0.009)GT(0.011)LVQEGGS(0.97)PIKYNK ; 94.495 3.40E-08 52661000 3743.5 2918.6 3171.3 3435.7 3634.6 7556.6 4687.1 3055.8 4680.6 3048.1 TRUE FALSE FALSE 3447.198025 3170.870779 3288.831168 3421.483984 3591.259769 5989.27598 4818.607411 3987.499353 4167.14989 3154.021248 1.09295333 1.005342238 1.042742236 1.08480055 1.138628908 1.898933301 1.527766312 1.264258874 1.321218078 1 11.62297666 -5.429212843 6.950247043 1.046696766 1.558746696 0.608264885 0.169301511 0.096968786 6.205052134 0.019975673 0.044848145 3.72E-06 5.429212843 0.51204993 AGGAS(ph)PAASSTAQPPTQHR ddPTM_HeLa_Curcumin_4h_R1 4 AGGASPAASSTAQPPTQHR 19 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 0 AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR;AGGAS(1)PAASSTAQPPTQHR ;;; 160.47 9.24E-06 386076500 9784.8 7824.62 7693.86 8033.53 9096.6 10603.9 7199.88 3913.39 9816.33 8097 TRUE FALSE FALSE 9010.322755 8500.945287 7979.00122 8000.289381 8988.128986 8404.531609 7401.889255 5106.564596 8739.503158 8378.370147 1.075426676 1.01462995 0.952333339 0.954874187 1.072777739 1.0031225 0.883452166 0.609493792 1.043103015 1 13.03245391 -4.275514986 1.79649832 1.025008461 0.478243305 0.902770835 0.040437964 0.20444143 0.668024045 0.006773225 0.187104826 5.30E-05 4.275514986 -0.546765156 AGGDATDS(ph)SQTALDNK ddPTM_HeLa_Curcumin_4h_R1 1 AGGDATDSSQTALDNK 16 0 E3W994;J3KR49;O75122;E7ERI8;E7EW49;O75122-3;A0A0U1RQI6;H7C4X8 E3W994 CLASP2 CLIP-associating protein 2 1 0 AGGDAT(0.001)DS(0.852)S(0.083)QT(0.064)ALDNK 178.14 2.56E-16 0 1512.9 1500.6 1177.6 1594.2 1633.4 1964.3 1360.4 1526.4 1501.5 1347.3 TRUE FALSE FALSE 1393.152369 1630.305177 1221.242892 1587.603623 1613.922772 1556.882038 1398.569163 1991.792333 1336.789207 1394.118575 0.999306941 1.169416438 0.875996428 1.138786651 1.157665353 1.116750086 1.003192403 1.42871085 0.958877696 1 10.44513756 -2.05447399 1.387267235 1.026621573 200 0.567584448 0.096486638 378.8652045 1.855729387 0.013537508 238735.4828 0.008821166 2.05447399 198.9733784 AGGDLSLS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 3 AGGDLSLSPGR 11 0 A0A1B0GTT1;A0A1B0GVM0;Q9BUH8 A0A1B0GTT1 BEGAIN Brain-enriched guanylate kinase-associated protein 1 0 AGGDLSLS(1)PGR;AGGDLSLS(1)PGR;AGGDLSLS(1)PGR ;; 168.83 0.00024822 245736000 9634 7340.8 7798.5 8363.7 7881 7252.5 4964.5 3484.37 9527.9 7514.1 TRUE FALSE FALSE 8871.458734 7975.306042 8087.51927 8329.093225 7787.024222 5748.249747 5103.790509 4546.738373 8482.713208 7775.214416 1.140992166 1.025734548 1.040166719 1.071236468 1.001518904 0.739304338 0.656417976 0.584773375 1.09099412 1 12.92466675 -5.167545435 1.889924343 1.063927464 0.60959614 0.957616872 0.038615787 0.06731171 0.455796926 0.008080512 0.02860257 6.80E-06 5.167545435 -0.454331324 AGGEPWGAK(ac)KPR ddPTM_HeLa_Curcumin_4h_R1 2 AGGEPWGAKKPR 12 2 Q8N163-2;Q8N163;E5RHJ4 Q8N163-2 CCAR2 Cell cycle and apoptosis regulator protein 2 0 1 ; AGGEPWGAK(0.637)K(0.363)PR;AGGEPWGAK(0.981)K(0.019)PR 160.91 2.42E-06 18687200 5868.4 4581.1 5325.8 4881.2 5691.2 7864.4 7428.6 7994.7 5670.8 5234.3 FALSE TRUE FALSE 5403.909948 4977.069871 5523.178833 4861.002888 5623.336157 6233.23479 7637.026523 10432.24723 5048.727428 5416.191535 0.997732431 0.918924273 1.019753234 0.897494643 1.038245439 1.150851987 1.410036272 1.926122287 0.932154521 1 12.40306304 -4.221400499 1.178281653 0.98690443 2.434770085 0.978254957 0.044370648 0.150232843 0.159687277 0.006077263 0.272119578 6.01E-05 4.221400499 1.447865656 AGGFLMK ddPTM_HeLa_Curcumin_4h_R1 2 AGGFLMK 7 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 0 ; ; 130.84 0.0076579 10246400 5417.7 3634.4 4921 4075.5 5079.2 4776.3 4930.9 5049.7 4523 3732.8 FALSE FALSE TRUE 4988.883328 3948.541341 5103.376589 4058.636661 5018.633857 3785.64154 5069.247783 6589.330284 4026.838216 3862.514522 1.291615423 1.022272232 1.32125758 1.050775767 1.299317796 0.980097685 1.312421676 1.705969064 1.042543191 1 11.91532464 -4.343433756 3.113902857 1.142073801 1.745372163 0.655110551 0.127119803 0.147002228 2.239721007 0.018612202 0.191867815 4.53E-05 4.343433756 0.603298362 AGGGGGLGAGS(ph)PALSGGQGR ddPTM_HeLa_Curcumin_4h_R1 2 AGGGGGLGAGSPALSGGQGR 20 0 A0A3B3ITT1;Q6IQ22 A0A3B3ITT1 RAB12 Ras-related protein Rab-12 1 0 AGGGGGLGAGS(0.997)PALS(0.003)GGQGR;AGGGGGLGAGS(1)PALSGGQGR ; 222.93 2.97E-19 99359000 7460.6 6627.6 6901.1 7887.8 7209.7 10132.6 6598.4 1445.86 8167.3 6299 TRUE FALSE FALSE 6870.085638 7200.460212 7156.860837 7855.162374 7123.729036 8030.984542 6783.533345 1886.696058 7271.367624 6517.889781 1.054035258 1.10472261 1.098033424 1.205169562 1.092950215 1.232144883 1.040756069 0.289464247 1.115601501 1 12.67018924 -4.26276615 6.012713657 1.067859286 0.269069473 0.913066153 0.074741164 0.030918742 5.403427006 0.011934479 0.10075645 5.46E-05 4.26276615 -0.798789813 AGGIETIANEYSDR ddPTM_HeLa_Curcumin_4h_R1 1 AGGIETIANEYSDR 14 0 P34932;A0A087WYC1;A0A087WTS8;P34932-2 P34932 HSPA4 Heat shock 70 kDa protein 4 0 0 178.54 0.0013067 5271800 1366.5 965.81 1150.5 1347.4 1166.1 1435.2 1022.4 957.92 1106.1 1044.4 FALSE FALSE TRUE 1258.340083 1049.290313 1193.138542 1341.824816 1152.195019 1137.523342 1051.085792 1249.985398 984.7635973 1080.692822 1.164382753 0.970942243 1.104049659 1.241633874 1.066163294 1.052587117 0.972603658 1.156651893 0.911233587 1 10.07774079 -3.923161606 19.0311553 1.076571925 3.478651352 0.050191708 0.095687973 470.0761848 126755.1253 0.012026857 4242.765283 0.000119354 3.923161606 2.402079427 AGGK(ac)AGK(ac)DSGK ddPTM_HeLa_Curcumin_4h_R1 4 AGGKAGKDSGK 11 2 A0A494C189;P0C0S5;C9J0D1;Q71UI9-2;Q71UI9;C9J386;Q71UI9-3;Q71UI9-5 A0A494C189;C9J0D1 H2AFZ;H2AFV Histone H2A.Z;Histone H2A;Histone H2A.V 0 2 ;;; AGGK(1)AGK(1)DSGK;AGGK(1)AGK(1)DSGK;AGGK(1)AGK(1)DSGK;AGGK(1)AGK(1)DSGK 143.97 3.99E-05 60782900 8652.29 8861.03 9797.72 7312.89 8356.5 9500.95 8967.73 5605.94 8555.35 8383.04 FALSE TRUE FALSE 7967.452117 9626.937949 10160.83212 7282.631199 8256.854195 7530.345872 9219.340368 7315.165299 7616.849509 8674.350016 0.918507105 1.109816635 1.171365244 0.839559297 0.951870074 0.868116442 1.062827803 0.843309906 0.87808879 1 13.08253994 AGGK(ac)AGK(ac)DSGK(ac)AK ddPTM_HeLa_Curcumin_4h_R1 4 AGGKAGKDSGKAK 13 3 A0A494C189;P0C0S5;C9J0D1;Q71UI9-2;Q71UI9;C9J386;Q71UI9-3;Q71UI9-5 A0A494C189;C9J0D1 H2AFZ;H2AFV Histone H2A.Z;Histone H2A;Histone H2A.V 0 3 ;;; AGGK(1)AGK(1)DSGK(1)AK;AGGK(1)AGK(1)DSGK(1)AK;AGGK(1)AGK(1)DSGK(1)AK;AGGK(1)AGK(1)DSGK(1)AK 166.7 6.79E-06 13458700 6401.15 11777.92 7050.42 7917.24 6188.71 8143.95 11607.17 6481.91 7719.58 6484.04 FALSE TRUE FALSE 5894.492223 12795.95092 7311.714767 7884.480559 6114.913675 6454.802969 11932.83595 8458.21452 6872.761387 6709.359907 0.878547627 1.90717909 1.08977829 1.175146462 0.911400455 0.96205943 1.778535675 1.260658936 1.024354258 1 12.71195942 -1.000000013 0.154295187 0.877550079 2.928706951 0.042128911 0.334100462 93.18138667 0.920921111 0.6896083 43.25287972 0.099999997 1.000000013 2.051156872 AGGKPSQS(ph)PSQEAAGEAVLGAK ddPTM_HeLa_Curcumin_4h_R1 1 AGGKPSQSPSQEAAGEAVLGAK 22 1 P00519;P00519-2 P00519 ABL1 Tyrosine-protein kinase ABL1 1 0 AGGKPS(0.046)QS(0.559)PS(0.395)QEAAGEAVLGAK 61.087 0.0037855 7522400 1929.5 1995.4 1652.3 1798.1 1714.2 2350.7 1502.9 1264.7 1684.9 1562.4 TRUE FALSE FALSE 1776.778039 2167.873485 1713.535692 1790.659939 1693.759285 1863.138322 1545.067329 1650.301208 1500.070685 1616.693284 1.099019868 1.340930594 1.059901534 1.107606469 1.047668906 1.15243772 0.955696015 1.020788065 0.927863498 1 10.65883028 -3.119488994 11.56701465 1.070339933 1.025838012 0 0.11119329 0 1.22E-09 0.014115701 5497131.233 0.000759471 3.119488994 -0.044501921 AGGKPSQSPS(ph)QEAAGEAVLGAK ddPTM_HeLa_Curcumin_4h_R1 1 AGGKPSQSPSQEAAGEAVLGAK 22 1 P00519;P00519-2 P00519 ABL1 Tyrosine-protein kinase ABL1 1 0 AGGKPS(0.022)QS(0.414)PS(0.565)QEAAGEAVLGAK 53.777 0.0074154 7707700 3504.9 2641.1 2814.1 2929 2980.9 3511.5 2467.8 2733.6 3267.8 3176 TRUE FALSE FALSE 3227.483467 2869.384915 2918.393022 2916.880574 2945.354714 2783.175317 2537.039826 3567.062056 2909.330516 3286.365764 0.982082853 0.873117943 0.888030497 0.887570278 0.896234603 0.84688544 0.771989489 1.085412371 0.88527289 1 11.68227734 -7.302086598 5.661499557 0.991930088 0.886044589 0.058868484 0.081290672 0.167312851 14.37121064 0.011596029 0.01334381 4.99E-08 7.302086598 -0.105885499 AGGLDWPEATEVS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 AGGLDWPEATEVSPSR 16 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 0 AGGLDWPEAT(0.005)EVS(0.979)PS(0.016)R 263.04 1.08E-51 110350000 2690 2239.1 2070 2162.7 2130.5 2678.1 2123.1 368.78 2125.2 1830.9 TRUE FALSE FALSE 2477.083662 2432.637827 2146.716021 2153.75132 2105.095179 2122.631872 2182.668472 481.2193243 1892.070877 1894.523639 1.307496835 1.284036671 1.133116514 1.136830006 1.111147486 1.120404005 1.152093554 0.254005447 0.998705341 1 10.88761943 -4.261438501 14.46313043 1.152227616 0.253858219 0.884636802 0.095669814 0.014583218 1010.274384 0.016499478 0.126819187 5.48E-05 4.261438501 -0.898369397 ASPS(ph)PQPSSQPLQIHR ddPTM_HeLa_Curcumin_4h_R1 3 ASPSPQPSSQPLQIHR 16 0 B5MBZ0;Q9HC35 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 0 AS(0.417)PS(0.583)PQPSSQPLQIHR;AS(0.016)PS(0.98)PQPSS(0.003)QPLQIHR;AS(0.188)PS(0.812)PQPSSQPLQIHR ;; 180.56 1.53E-05 83187000 5888.25 5224.08 5534.9 5409.1 3904.03 2712.89 1670.25 1163.61 6097.22 5570.27 TRUE FALSE FALSE 5422.188799 5675.626197 5740.028263 5386.718577 3857.476992 2150.206033 1717.11272 1518.389332 5428.37022 5763.836468 0.940725649 0.98469591 0.995869382 0.934571723 0.669255107 0.373051187 0.297911422 0.263433798 0.941798098 1 12.49281369 -5.440692295 1.729146801 0.975643179 0.276150398 0.994147595 0.022616763 0.021724537 0.1259047 0.004123723 0.012022392 3.62E-06 5.440692295 -0.699492781 down AGGPAT(ph)PLS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 AGGPATPLSPTR 12 0 Q03252 Q03252 LMNB2 Lamin-B2 2 0 AGGPAT(1)PLS(0.997)PT(0.003)R 135.94 0.0076835 68278000 7019.3 5846.6 5738.6 5989.3 6398.3 12293 12530 5190.6 7386.9 4599.2 TRUE FALSE FALSE 6463.714998 6351.954052 5951.277564 5964.517864 6322.004451 9743.293229 12881.55808 6773.190045 6576.575551 4759.021858 1.358202419 1.334718403 1.250525369 1.253307516 1.328425177 2.047331053 2.706765899 1.423231548 1.381917492 1 12.21644937 -5.280274957 3.879620049 1.202715012 2.138217119 0.570123401 0.309264963 0.098515315 3.36016652 0.041995592 0.104941933 5.24E-06 5.280274957 0.935502107 AGGPAT(ph)PLSPTR ddPTM_HeLa_Curcumin_4h_R1 1 AGGPATPLSPTR 12 0 Q03252 Q03252 LMNB2 Lamin-B2 1 0 AGGPAT(0.999)PLS(0.001)PTR 140.45 0.003426 25358000 3349.6 2479.2 2871.9 2629.1 2382.9 3643.1 2997.3 9347.9 3128 3070.5 TRUE FALSE FALSE 3084.475626 2693.491001 2978.33514 2618.221481 2354.485474 2887.479994 3081.396171 12198.03168 2784.866226 3177.199646 0.970815803 0.847756295 0.937408873 0.824065772 0.741056822 0.90881289 0.969846567 3.839239908 0.876515969 1 11.63354003 -4.261440977 7.566266946 0.939310791 3.86973654 0.99101041 0.083977029 0.007256276 4.10443663 0.013480093 0.108010147 5.48E-05 4.261440977 2.930425749 AGGPATPLS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 AGGPATPLSPTR 12 0 Q03252 Q03252 LMNB2 Lamin-B2 1 0 AGGPAT(0.002)PLS(0.973)PT(0.026)R 120.6 0.0035038 70146000 2600.1 2024.2 2352.7 2186.8 2378.3 2842.9 1358.2 1758 2225.7 2296.5 TRUE FALSE FALSE 2394.299341 2199.162828 2439.893132 2177.751601 2349.940326 2253.250494 1396.307437 2294.006107 1981.546278 2376.303204 1.007573165 0.925455483 1.026760023 0.916445173 0.988905928 0.948216747 0.587596496 0.965367594 0.833877712 1 11.21450321 -4.975415661 24.76447844 0.991014824 0.774337936 0.287829493 0.103707524 107.8974593 108686.5549 0.010830063 0.032488254 1.06E-05 4.975415661 -0.216676888 ADS(ph)PAGPESSRR ddPTM_HeLa_Curcumin_4h_R1 2 ADSPAGPESSRR 12 1 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 0 ADS(1)PAGPESSRR;ADS(1)PAGPESSRR ; 101.2 0.0040433 12171200 4370.4 4132.6 3939.9 4063.9 2904.4 2643.8 1665.9 1075.78 4614.2 3823.7 TRUE FALSE FALSE 4024.478228 4489.803529 4085.91616 4047.084659 2869.766927 2095.446078 1712.64067 1403.78037 4108.033804 3956.57329 1.017162563 1.134770722 1.032690629 1.022876202 0.725316256 0.529611339 0.432859584 0.354797009 1.03828073 1 11.95003577 -5.412187126 1.62944286 1.024367604 0.395834294 0.970433442 0.04750276 0.047881924 0.244310547 0.007698602 0.023761047 3.87E-06 5.412187126 -0.628533311 down AGGPTT(ph)PLS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 AGGPTTPLSPTR 12 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 2 0 AGGPT(0.001)T(0.998)PLS(0.972)PT(0.029)R 116.98 0.017442 316880000 7466 6191 6549.7 6977.7 7127.9 12478 11997 4784.9 8101.8 5253.9 TRUE FALSE FALSE 6875.058222 6726.122453 6792.437644 6948.828126 7042.904448 9889.922144 12333.60353 6243.793983 7213.05281 5436.472634 1.264617462 1.237221799 1.249420001 1.278186904 1.295491566 1.819179974 2.268677571 1.14850095 1.326789132 1 12.40845517 -5.363758617 3.377505593 1.160265103 1.799740092 0.409243919 0.271844712 0.142052843 3.035802233 0.037161211 0.090345234 4.33E-06 5.363758617 0.639474989 AGGPTT(ph)PLSPTR ddPTM_HeLa_Curcumin_4h_R1 1 AGGPTTPLSPTR 12 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 1 0 AGGPT(0.169)T(0.831)PLSPTR 118.87 0.010672 61490000 2916.7 2449.1 2929.4 2543 2441.1 3340.1 2664.2 9755.7 3117.3 2928.3 TRUE FALSE FALSE 2685.840117 2660.789291 3037.966141 2532.47774 2411.991477 2647.325609 2738.950282 12730.16802 2775.339989 3030.058207 0.886398852 0.878131412 1.002609829 0.835785179 0.796021499 0.873688038 0.903926623 4.201294876 0.915936196 1 11.56512979 -4.261267056 24.99943908 0.920198353 4.201295846 0.995831412 0.064080916 0.698886119 101306.1943 0.01055468 0.081732277 5.48E-05 4.261267056 3.281097493 AGGPTTPLS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 3 AGGPTTPLSPTR 12 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 1 0 AGGPTTPLS(0.88)PT(0.12)R;AGGPT(0.001)T(0.002)PLS(0.793)PT(0.205)R;AGGPTT(0.003)PLS(0.683)PT(0.314)R ;; 101.38 0.0085278 811555000 6557.6 5628 5675.8 6137.4 5841.5 5832.6 3551.4 3273.23 6824.1 6213.7 TRUE FALSE FALSE 6038.55904 6114.459242 5886.150141 6112.005065 5771.843928 4622.853013 3651.042726 4271.222759 6075.513303 6429.625612 0.939177396 0.950982158 0.915473232 0.95060046 0.897695181 0.718992565 0.567846862 0.664303494 0.944924894 1 12.65051902 -5.218545603 2.051585056 0.963133071 0.612755974 0.945839998 0.03269318 0.052842814 0.425580896 0.005323073 0.017139801 6.05E-06 5.218545603 -0.350377097 AGGS(ph)PAPGPETPAISPSKR ddPTM_HeLa_Curcumin_4h_R1 1 AGGSPAPGPETPAISPSKR 19 1 P33316;H0YKI0 P33316 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 1 0 AGGS(1)PAPGPETPAISPSKR 159.26 1.06E-05 21148000 1793.5 1372.6 1471.7 1383.5 1667.2 2105.9 1765.8 1397.5 1958.1 1539.2 TRUE FALSE FALSE 1651.542583 1491.241428 1526.242497 1377.775444 1647.319729 1669.112602 1815.343596 1823.591317 1743.301329 1592.687085 1.036953585 0.936305343 0.958281454 0.865063487 1.034302183 1.047985268 1.139799281 1.144977776 1.094566123 1 10.63724713 -4.916786678 2.146028364 0.99631581 1.149138687 0.512917631 0.059090903 0.201063171 1.787845173 0.008212242 0.035585604 1.21E-05 4.916786678 0.152822876 AGGSAALS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 AGGSAALSPSK 11 0 Q92522 Q92522 H1FX Histone H1x 1 0 AGGSAALS(0.974)PS(0.026)K;AGGS(0.199)AALS(0.788)PS(0.013)K ; 145.31 0.00098498 1044680000 19854 11636.8 14856.8 14499.2 16214.3 17667.6 15376.4 8799.2 15740.4 13748.7 TRUE FALSE FALSE 18282.53495 12642.63314 15407.40608 14439.20615 16020.95506 14003.14061 15807.8204 11482.03557 14013.7175 14226.4663 1.285107247 0.888669953 1.083010057 1.014953808 1.12613735 0.984302096 1.11115579 0.807089781 0.985045563 1 13.79628974 -7.254062545 24.85801056 1.134633978 1.0140583 0.058402497 0.122202148 754.7559945 2543330.191 0.022195733 0.026890402 5.57E-08 7.254062545 -0.120575678 AGGSPAPGPETPAIS(ph)PSKR ddPTM_HeLa_Curcumin_4h_R1 4 AGGSPAPGPETPAISPSKR 19 1 P33316;H0YKI0 P33316 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 1 0 AGGS(0.051)PAPGPET(0.083)PAIS(0.682)PS(0.185)KR;AGGSPAPGPET(0.004)PAIS(0.788)PS(0.208)KR;AGGSPAPGPETPAIS(0.91)PS(0.089)KR;AGGSPAPGPET(0.001)PAIS(0.683)PS(0.315)KR ;;; 164.5 1.58E-05 73095700 12363.9 10495.7 10043.8 11610.6 11434.16 14344.8 10498.5 10526.43 13900 10768.8 TRUE FALSE FALSE 11385.28427 11402.90154 10416.03206 11562.55841 11297.81511 11369.52678 10793.05965 13735.89005 12375.20478 11143.015 1.021741806 1.023322821 0.934758866 1.037650799 1.013892121 1.020327692 0.968594196 1.232690618 1.110579567 1 13.44385202 -4.255468591 24.958936 1.006949071 1.232690719 0.68868348 0.043734208 170.5414044 712871.8797 0.003722032 0.04519837 5.55E-05 4.255468591 0.225741648 HGLQSLGK(ac)VGISR ddPTM_HeLa_Curcumin_4h_R1 2 HGLQSLGKVGISR 13 1 E7EPN9;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3 E7EPN9 PRRC2C Protein PRRC2C 0 1 ; HGLQSLGK(1)VGISR;HGLQSLGK(1)VGISR 126.1 0.0014344 5915900 3523.4 4272.8 2905.8 2947.8 4026.1 8300.9 5154.9 5446.1 4616.6 2860.8 FALSE TRUE FALSE 3244.519172 4642.121793 3013.491504 2935.602785 3978.091387 6579.19977 5299.53262 7106.590819 4110.17053 2960.212587 1.096042624 1.568171763 1.017998342 0.991686475 1.343853277 2.222543002 1.790254066 2.400702858 1.388471405 1 11.53148507 -5.38147434 3.616152142 1.085970154 2.105497215 0.763760427 0.236104204 0.070811449 1.671893616 0.030429404 0.072420496 4.15E-06 5.38147434 1.019527061 VAPSK(ac)LEALQK ddPTM_HeLa_Curcumin_4h_R1 2 VAPSKLEALQK 11 1 A0A5H1ZRP4;Q8WX92;Q8WX92-2 A0A5H1ZRP4 NELFB Negative elongation factor B 0 1 ; VAPSK(1)LEALQK;VAPSK(1)LEALQK 134.75 0.000487 4749900 3265.9 2225.63 2269.8 2077.01 2285.8 2223.1 1878.84 865.72 2642.9 2508.3 FALSE TRUE FALSE 3007.400569 2418.00354 2353.920785 2068.415883 2258.543328 1762.004 1931.555194 1129.674043 2352.980482 2595.463238 1.158714377 0.931626965 0.906936669 0.796935149 0.870188911 0.678878427 0.744204412 0.435249487 0.906574382 1 11.34177634 -5.060303232 0.477133676 1.075507358 0.371185666 0.722980571 0.097920328 0.786815793 0.193113563 0.023627987 0.272347823 8.70E-06 5.060303232 -0.704321692 AGHY(ph)AAS(ph)IIIRRT(ph)GCT(ph)FPEK ddPTM_HeLa_Curcumin_4h_R1 1 AGHYAASIIIRRTGCTFPEK 20 2 A0A5F9ZHJ1;P55263-3;P55263-4;P55263-2;P55263 A0A5F9ZHJ1 ADK Adenosine kinase 4 0 AGHY(1)AAS(1)IIIRRT(1)GCT(1)FPEK 52.321 0.009221 12761000 794.76 906.71 858.32 1014.2 878.94 912.01 836.79 721.59 952.68 878.94 TRUE FALSE FALSE 731.8539074 985.0819722 890.1300943 1010.003509 868.4592146 722.8488455 860.2680753 941.5994692 848.1733875 909.4830996 0.804692146 1.0831229 0.978720874 1.110524769 0.954893186 0.79479085 0.945886818 1.035312772 0.932588399 1 9.828903019 -7.261192721 24.99997465 0.907771293 0.980560497 0.114027609 0.09302136 43.81565182 4441032.092 0.018601797 0.02201136 5.48E-08 7.261192721 0.072789203 AGIIAS(ph)AR ddPTM_HeLa_Curcumin_4h_R1 1 AGIIASAR 8 0 P13639 P13639 EEF2 Elongation factor 2 1 0 AGIIAS(1)AR 104.01 0.013044 3272200 2850.2 2127.1 2502.4 2710.8 2475.9 3010.7 2453.4 1719.4 2807.3 2689 TRUE FALSE FALSE 2624.603662 2310.957046 2595.141145 2699.583428 2446.37651 2386.246882 2522.235801 2243.637145 2499.346214 2782.44255 0.943273263 0.830549779 0.932684538 0.970220725 0.879219055 0.85760868 0.906482616 0.806355245 0.898256179 1 11.44213618 -1 0.044720238 1.269131655 0.283895086 0.146902642 0.053600668 290.6739113 0.996269068 5.671090942 20.78996003 0.1 1 -0.98523657 NLEPGK(ac)QISR ddPTM_HeLa_Curcumin_4h_R1 1 NLEPGKQISR 10 1 Q9UER7-3;Q9UER7;Q9UER7-2;Q9UER7-5;Q9UER7-4 Q9UER7-3 DAXX Death domain-associated protein 6 0 1 NLEPGK(1)QISR 120.09 0.002877 3740400 1734.3 1695.2 1446.7 1909.4 1945.1 3011 4162.8 3612.1 1784.8 1621.1 FALSE TRUE FALSE 1597.028325 1841.725534 1500.315975 1901.499409 1921.905953 2386.484659 4279.596964 4713.412662 1589.011905 1677.433104 0.952066774 1.097942761 0.894411807 1.133576894 1.145742234 1.422700347 2.551277278 2.809896055 0.947287794 1 10.71203952 -4.792966602 1.916574725 0.996915462 2.883749566 0.983416529 0.085047682 0.029963907 0.201234716 0.012071218 0.069136096 1.61E-05 4.792966602 1.886834104 up AGK(ac)DSGK(ac)AK(ac)AK ddPTM_HeLa_Curcumin_4h_R1 2 AGKDSGKAKAK 11 3 C9J0D1;Q71UI9-2;Q71UI9;C9J386;Q71UI9-3;Q71UI9-5 C9J0D1 H2AFV Histone H2A;Histone H2A.V 0 3 ; AGK(1)DSGK(1)AK(1)AK;AGK(1)DSGK(1)AK(1)AK 122.55 0.0057991 4201200 2202.12 2182.75 2000.05 2073.88 2482.8 3278.6 4228.6 3618.9 3077 2143.5 FALSE TRUE FALSE 2027.819878 2371.417184 2074.173612 2065.298834 2453.194232 2598.581403 4347.243135 4722.285951 2739.460798 2217.986465 0.914261611 1.069175678 0.935160626 0.931159349 1.106045627 1.171594797 1.959995339 2.12908691 1.235111594 1 11.11503485 -4.771581909 2.285244802 0.971252488 2.151731672 0.937042645 0.103832099 0.030726996 0.305746313 0.009378689 0.047755346 1.69E-05 4.771581909 1.180479184 up AGK(ac)FPSLLTHNENMVAK ddPTM_HeLa_Curcumin_4h_R1 1 AGKFPSLLTHNENMVAK 17 1 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 1 AGK(1)FPSLLTHNENMVAK 107.98 0.00052086 1805900 183.78 343.25 282.89 179.04 334.43 335.56 241.97 296.16 385.52 313.27 FALSE TRUE FALSE 169.2336191 372.9190005 293.3741523 178.2991799 330.4421407 265.9610735 248.759027 386.4578206 343.2294205 324.1561092 0.52207444 1.150430271 0.905039714 0.550041091 1.019391988 0.820472192 0.767405025 1.192196629 1.058839895 1 8.340544953 -4.257554919 23.7104594 0.808017598 1.192196927 0.134681465 0.205238352 229.5057454 1400759.27 0.030329119 0.30179312 5.53E-05 4.257554919 0.38417933 AGK(ac)DSGK(ac)AK(ac)TK ddPTM_HeLa_Curcumin_4h_R1 2 AGKDSGKAKTK 11 3 A0A494C189;P0C0S5 A0A494C189 H2AFZ Histone H2A.Z 0 3 ; AGK(1)DSGK(1)AK(1)TK;AGK(1)DSGK(1)AK(1)TK 190.66 1.70E-21 45321000 10496.5 7981.3 8934.2 8796.1 9231.5 9794.8 16614.3 14977.4 9199.8 7582.7 FALSE TRUE FALSE 9665.690949 8671.168008 9265.309311 8759.704069 9121.420392 7763.24807 17080.45254 19543.94031 8190.604957 7846.198261 1.231894814 1.105142608 1.180866071 1.116426552 1.162527391 0.989427977 2.176908099 2.490880254 1.043894723 1 12.93777808 -4.68986224 4.567648676 1.113823656 2.408364359 0.969496665 0.087740877 0.026284644 1.020656843 0.014344919 0.05734398 2.04E-05 4.68986224 1.294540703 up AGKK(ac)VK(ac)LSHEEVMQK ddPTM_HeLa_Curcumin_4h_R1 1 AGKKVKLSHEEVMQK 15 3 A0A087WXU0;A0A2R8Y4J4;Q9NWS8-2;Q9NWS8 A0A087WXU0 RMND1 Required for meiotic nuclear division protein 1 homolog 0 2 AGK(0.218)K(0.891)VK(0.891)LSHEEVMQK 64.394 0.01202 0 576.05 317.41 601.71 713.75 550.72 749.37 524.71 665.08 518.4 496.76 FALSE TRUE FALSE 530.4550347 344.845506 624.0099019 710.7966916 544.1530237 593.9422149 539.4319504 867.8598303 461.532817 514.022373 1.031968767 0.670876452 1.213974206 1.382812751 1.058617391 1.155479306 1.049432824 1.68836976 0.897884686 1 9.005687344 -6.558438756 24.99836596 0.987450361 1.243222926 0.404359747 0.201830177 163.1537845 114695.0751 0.029612229 0.041878093 2.76E-07 6.558438756 0.255772565 AGKPVICATQMLESMIK ddPTM_HeLa_Curcumin_4h_R1 1 AGKPVICATQMLESMIK 17 1 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BR70 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 128.64 6.88E-05 1278300 192.57 275.86 360.86 344.5 417.72 315.62 377.41 200.3 409.32 319.01 FALSE FALSE TRUE 177.3278813 299.7041092 374.233789 343.0745503 412.7389618 250.1568542 387.9991089 261.3705479 364.4186201 330.0955738 0.537201633 0.907931318 1.133713442 1.039318844 1.250362 0.757831592 1.175414455 0.791802644 1.103979117 1 8.366739983 -7.001114608 24.58363676 0.778356862 1.029579223 0.033115447 0.206069794 37.96256159 837327.3666 0.034511304 0.045019717 9.97E-08 7.001114608 0.251222361 AGKSGTST(ph)PTTPGS(ph)TAITPGTPPSYSSR ddPTM_HeLa_Curcumin_4h_R1 1 AGKSGTSTPTTPGSTAITPGTPPSYSSR 28 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 2 0 AGKS(0.108)GT(0.291)S(0.307)T(0.327)PT(0.256)T(0.256)PGS(0.241)T(0.212)AIT(0.002)PGT(0.001)PPSYSSR 62.039 0.0030518 5446300 913.24 633.77 670.08 830.59 702.9 862.97 570.34 444.53 697.84 1064.3 TRUE FALSE FALSE 840.9560904 688.5502548 694.9137543 827.1532387 694.5183766 683.9802943 586.3422054 580.0651506 621.2886979 1101.284346 0.763613951 0.625224773 0.631003026 0.751080538 0.630644011 0.621075108 0.532416726 0.526716967 0.564149214 1 10.1049713 -13.52287875 0.080997365 2.368218367 0.228138321 0 0.148101106 35.29786236 0.219166855 8.517656043 0.919086917 3.00E-14 13.52287875 -2.140080046 AGLAS(ph)PEEEDAVGKEPLK ddPTM_HeLa_Curcumin_4h_R1 1 AGLASPEEEDAVGKEPLK 18 1 Q9UNS1-2;Q9UNS1 Q9UNS1-2 TIMELESS Protein timeless homolog 1 0 AGLAS(1)PEEEDAVGKEPLK 61.181 0.011641 9529000 1634.1 1506.8 1882.1 1738.9 1833.1 2130.1 1593.8 1647.9 1789.4 1917.1 TRUE FALSE FALSE 1504.759261 1637.041078 1951.852282 1731.704893 1811.24148 1688.293249 1638.517739 2150.337124 1593.107297 1983.719082 0.758554613 0.825238358 0.98393583 0.872958731 0.913053414 0.851074764 0.825982748 1.08399276 0.803091179 1 10.95399202 -4.2510292 23.73209858 0.881949595 1.083992995 0.424038196 0.073574493 726.7066305 1656605.247 0.013060546 0.232955012 5.61E-05 4.2510292 0.2020434 AGLES(ph)GAEPGDGDS(ph)DTTKKK ddPTM_HeLa_Curcumin_4h_R1 1 AGLESGAEPGDGDSDTTKKK 20 2 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 2 0 AGLES(1)GAEPGDGDS(0.916)DT(0.045)T(0.04)KKK 61.437 0.010993 10703000 3311.5 2860.7 3101.4 3234.3 2575.9 3630 2529.4 2635.9 4168.7 3467.1 TRUE FALSE FALSE 3049.391281 3107.966161 3216.340612 3220.917324 2545.184075 2877.097081 2600.368156 3439.573776 3711.40404 3587.581467 0.849985236 0.866312358 0.896520579 0.897796288 0.709442865 0.801960069 0.724824838 0.958744438 1.034514219 1 11.80879588 -10.07738047 0.248595876 1.154680769 0.799504626 0.498843711 0.072559168 5.840359576 0.344056357 0.637263058 0.057422869 8.37E-11 10.07738047 -0.355176143 AGLES(ph)GAEPGDGDSDT(ph)TK ddPTM_HeLa_Curcumin_4h_R1 1 AGLESGAEPGDGDSDTTK 18 0 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 2 0 AGLES(1)GAEPGDGDS(0.202)DT(0.665)T(0.133)K 187.04 6.04E-07 13874000 3169.3 2791.5 2967 3383.3 3341.2 3061.7 2947.3 2238.7 2759.8 2860.6 TRUE FALSE FALSE 2918.446561 3032.784821 3076.95963 3369.300801 3301.358372 2426.668908 3029.993306 2921.269324 2457.056845 2960.005637 0.985959798 1.024587515 1.039511409 1.13827513 1.11532165 0.819819016 1.023644438 0.986913433 0.830085191 1 11.53138421 -5.281062502 24.99553934 1.017360332 0.951477464 0.122032079 0.092150314 1204.089153 1533743.112 0.010722614 0.024010765 5.24E-06 5.281062502 -0.065882867 AGLES(ph)GAEPGDGDSDTTKK ddPTM_HeLa_Curcumin_4h_R1 2 AGLESGAEPGDGDSDTTKK 19 1 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 0 AGLES(1)GAEPGDGDSDTTKK;AGLES(1)GAEPGDGDSDTTKK ; 127.37 6.18E-05 49652000 5104.3 4683.7 4972.6 4922.7 4689.5 5160.4 4105.7 2925.6 5166.6 5058.3 TRUE FALSE FALSE 4700.289269 5088.538158 5156.88893 4902.331172 4633.580775 4090.07487 4220.894892 3817.601972 4599.836906 5234.075548 0.898017085 0.972194251 0.985253056 0.936618344 0.885272047 0.781432143 0.806426054 0.729374641 0.878825088 1 12.35371903 -5.405493825 1.724588578 0.955127436 0.765291542 0.795422178 0.039122288 0.124955012 0.715828508 0.006339639 0.019050127 3.93E-06 5.405493825 -0.189835893 AGLESGAEPGDGDS(ph)DTTK ddPTM_HeLa_Curcumin_4h_R1 6 AGLESGAEPGDGDSDTTK 18 0 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 0 AGLESGAEPGDGDS(0.944)DT(0.035)T(0.02)K;AGLESGAEPGDGDS(0.993)DT(0.007)T(0.001)K;AGLESGAEPGDGDS(0.891)DT(0.085)T(0.025)K;AGLESGAEPGDGDS(0.991)DT(0.006)T(0.003)K;AGLESGAEPGDGDS(0.999)DT(0.001)TK;AGLESGAEPGDGDS(1)DTTK ;;;;; 284.15 1.13E-67 1835613300 20555.9 17952.8 20091.1 20793.3 20865.6 22954.7 19787.8 15328.8 21543 17967.8 TRUE FALSE FALSE 18928.87882 19504.56004 20835.69384 20707.26283 20616.79135 18193.63647 20342.99241 20002.48055 19179.7868 18592.17971 1.018109717 1.049073338 1.120669774 1.113761977 1.108895873 0.978563931 1.094169308 1.075854519 1.031605067 1 14.1824083 -7.14586565 2.97026629 1.0081209 1.080657448 0.356097184 0.038720768 0.190073999 3.20639728 0.00665366 0.008222882 7.15E-08 7.14586565 0.072536549 AGLESGAEPGDGDS(ph)DTTKK ddPTM_HeLa_Curcumin_4h_R1 2 AGLESGAEPGDGDSDTTKK 19 1 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 0 AGLESGAEPGDGDS(0.389)DT(0.389)T(0.221)KK;AGLES(0.17)GAEPGDGDS(0.709)DT(0.06)T(0.06)KK ; 100.76 0.00044288 667520000 5624.9 4950.3 5002.4 5679.3 5278.34 6299.1 4710.51 4425.42 5654.6 4588.5 TRUE FALSE FALSE 5179.68323 5378.181874 5187.793345 5655.800561 5215.399243 4992.595655 4842.674233 5774.710186 5034.304527 4747.950033 1.090930442 1.132737673 1.092638572 1.191208947 1.098452849 1.051526579 1.019950547 1.216253361 1.060311185 1 12.21308904 -8.732182851 0.704319117 1.000721908 1.110082516 0.218817927 0.058069222 0.584224533 0.562194099 0.033465918 0.012305024 1.85E-09 8.732182851 0.109360608 AGLESGAEPGDGDS(ph)DTTKKK ddPTM_HeLa_Curcumin_4h_R1 4 AGLESGAEPGDGDSDTTKKK 20 2 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 0 AGLESGAEPGDGDS(0.333)DT(0.333)T(0.333)KKK;AGLESGAEPGDGDS(0.964)DT(0.018)T(0.018)KKK;AGLESGAEPGDGDS(0.836)DT(0.082)T(0.082)KKK;AGLES(0.002)GAEPGDGDS(0.684)DT(0.083)T(0.231)KKK ;;; 101.05 0.00035907 623005000 15003.3 11888.6 12885.8 14095.3 12734.6 15792.1 12743.2 11857.6 15841.8 13825.3 TRUE FALSE FALSE 13815.77297 12916.19761 13363.35908 14036.97738 12582.74821 12516.64045 13100.7399 15472.92765 14103.99417 14305.72815 0.96575112 0.90286894 0.934126453 0.981213766 0.879560137 0.874939068 0.915768828 1.081589661 0.985898378 1 13.80430531 -7.865573387 1.224772403 0.991442557 0.934731722 0.113939679 0.056885501 0.542815594 1.705213742 0.013366264 0.01193937 1.36E-08 7.865573387 -0.056710835 AGLGSPERPPKTS(ph)PGSPR ddPTM_HeLa_Curcumin_4h_R1 1 AGLGSPERPPKTSPGSPR 18 2 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 0 AGLGSPERPPKT(0.013)S(0.734)PGS(0.252)PR 73.722 0.0079941 37102000 1990.4 1601.4 1887.1 2352.5 1647.2 2602.1 2400.3 2798 2444.4 1894.7 TRUE FALSE FALSE 1832.85774 1739.81788 1957.037586 2342.765978 1627.558216 2062.395128 2467.645958 3651.09732 2176.255436 1960.540684 0.934873606 0.887417382 0.998213198 1.194959124 0.830157838 1.051952222 1.258655828 1.862291025 1.110028194 1 10.93703586 -4.223362465 1.663620656 0.972715589 2.239075914 0.870434572 0.100636461 0.226093709 0.553100705 0.012591983 0.47049762 5.98E-05 4.223362465 1.266360326 AGLIGGVK ddPTM_HeLa_Curcumin_4h_R1 1 AGLIGGVK 8 0 F8WER1;A0A087WV24;P20711-2;P20711-3;P20711;H7BZF7 F8WER1 DDC Aromatic-L-amino-acid decarboxylase 0 0 95.957 0.017115 3225100 2217.1 2295.6 2137.1 2586.8 2110.7 805.3 1105.2 1166.9 2458.8 1956.2 FALSE FALSE TRUE 2041.614196 2494.021435 2216.302806 2576.096507 2085.531281 638.2717024 1136.208938 1522.682438 2189.075792 2024.177804 1.008614061 1.23211579 1.094915082 1.272663153 1.03031032 0.315323931 0.561318741 0.752247374 1.081464181 1 10.98312031 -5.282284925 22.55944023 1.050860854 0.544798997 0.774946507 0.136267183 83.66218467 90540.83215 0.020318976 0.045505623 5.22E-06 5.282284925 -0.506061856 AGLQFPVGR ddPTM_HeLa_Curcumin_4h_R1 2 AGLQFPVGR 9 0 Q93077;Q7L7L0;P04908;A0A3B3IS11;Q96QV6;Q8IUE6;A0A0U1RR32;A0A0U1RRH7;Q99878;Q96KK5;Q16777;Q6FI13;P20671;P0C0S8;Q9BTM1;Q9BTM1-2;P16104;A0A494C189;P0C0S5;C9J0D1;Q71UI9-2;Q71UI9;Q71UI9-5 Q93077;A0A0U1RR32;P16104;A0A494C189;C9J0D1 HIST1H2AC;HIST3H2A;HIST1H2AB;HIST1H2AA;HIST2H2AB;HIST1H2AJ;HIST1H2AH;HIST2H2AC;HIST2H2AA3;HIST1H2AD;HIST1H2AG;H2AFJ;H2AFX;H2AFZ;H2AFV Histone H2A type 1-C;Histone H2A type 3;Histone H2A type 1-B/E;Histone H2A type 1-A;Histone H2A type 2-B;Histone H2A type 1-J;Histone H2A type 1-H;Histone H2A type 2-C;Histone H2A type 2-A;Histone H2A type 1-D;Histone H2A type 1;Histone H2A.J;Histone H2AX;Histone H2A.Z;Histone H2A;Histone H2A.V 0 0 ; ; 166.05 1.36E-11 55442000 11056 5194.4 8890.3 6747.9 9786.5 10039.1 9100.4 6848.8 7385.3 7737.1 FALSE FALSE TRUE 10180.90593 5643.38079 9219.782339 6719.978978 9669.802379 7956.877496 9355.732732 8936.967592 6575.151067 8005.963649 1.271665271 0.704897129 1.151614314 0.839371657 1.207824917 0.993868801 1.168595455 1.116288805 0.821281654 1 12.96685935 -9.987613757 2.392626463 0.998433577 1.099707426 0.006815028 0.178054001 0.931821103 9.685528645 0.140573948 0.025442943 1.03E-10 9.987613757 0.101273849 AGLQMKS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 1 AGLQMKSPEK 10 1 Q9BRQ0 Q9BRQ0 PYGO2 Pygopus homolog 2 1 0 AGLQMKS(1)PEK 156.51 0.0060639 31083000 1597.6 1208 1209.5 1408.5 1477.4 1715 1511.6 1015.2 1753.1 1619 TRUE FALSE FALSE 1471.148274 1312.414137 1254.325134 1402.672 1459.78297 1359.289668 1554.011428 1324.729807 1560.789316 1675.260129 0.878161098 0.783409164 0.748734547 0.837286088 0.871376895 0.81139021 0.927623955 0.790760661 0.931669828 1 10.71016942 -8.397318002 0.843527316 0.986930521 0.829510366 0.512586969 0.052081002 0.26387707 0.393167086 0.020026209 0.011313681 4.01E-09 8.397318002 -0.157420155 AGLS(ph)PAEPLLSR ddPTM_HeLa_Curcumin_4h_R1 1 AGLSPAEPLLSR 12 0 O95402;B8ZZF3 O95402 MED26 Mediator of RNA polymerase II transcription subunit 26 1 0 AGLS(0.987)PAEPLLS(0.013)R 113.52 0.0045322 16950000 2848.3 2283.1 2486.9 2538.4 2398.2 2903.7 2442.8 2495.2 2753.1 2059.7 TRUE FALSE FALSE 2622.854049 2480.440991 2579.066702 2527.896773 2369.603031 2301.439889 2511.338394 3255.974994 2451.091818 2131.274422 1.230650555 1.163829944 1.210105407 1.186096332 1.111824459 1.079842119 1.178327093 1.527712696 1.150059229 1 11.05750065 -13.02709905 0.253659147 7.01E-16 1.226771071 0.118756387 0.123296135 33.32605784 0.554252338 16.65750874 0.067285039 9.40E-14 13.02709905 1.226771071 AGLS(ph)PANCQSDR ddPTM_HeLa_Curcumin_4h_R1 4 AGLSPANCQSDR 12 0 Q14692 Q14692 BMS1 Ribosome biogenesis protein BMS1 homolog 1 0 AGLS(0.966)PANCQS(0.034)DR;AGLS(0.812)PANCQS(0.188)DR;AGLS(1)PANCQSDR;AGLS(0.983)PANCQS(0.017)DR ;;; 145.61 0.00084213 147760000 6815.2 7335.9 7234.3 6931 7322.8 9854.5 6858.4 3346.08 7705.2 5650.2 TRUE FALSE FALSE 6275.769729 7969.982508 7502.409522 6902.321358 7235.480393 7810.565617 7050.828246 4366.284389 6859.958837 5846.544029 1.073415286 1.363195499 1.283221247 1.180581438 1.237565364 1.335928641 1.205982237 0.746814591 1.173335701 1 12.51336836 -7.473979501 9.914078571 1.032273944 1.205064426 0.063811777 0.167580482 0.669206799 132.9236588 0.027152428 0.03069594 3.36E-08 7.473979501 0.172790483 AGLSEEDDS(ph)LVDVYYR ddPTM_HeLa_Curcumin_4h_R1 1 AGLSEEDDSLVDVYYR 16 0 A0A3B3IUD7;Q14690 A0A3B3IUD7 PDCD11 Protein RRP5 homolog 1 0 AGLS(0.036)EEDDS(0.964)LVDVYYR 73.887 0.019852 4181100 596.77 559.22 613.32 563.74 776.1 684.46 667.86 506.26 520.51 476.49 TRUE FALSE FALSE 549.5350248 607.556485 636.0501787 561.4073933 766.8455144 542.4952805 686.5983541 660.6163435 463.4113553 493.047992 1.114567007 1.23224614 1.290037053 1.138646546 1.55531617 1.100288997 1.392558869 1.339862152 0.93989097 1 8.945584271 -7.299659568 0.554873006 1.011009626 1.335142282 0.543357262 0.120812358 0.400068355 0.283026323 0.038163618 0.04385455 5.02E-08 7.299659568 0.324132656 AGLVGPEFHEK ddPTM_HeLa_Curcumin_4h_R1 1 AGLVGPEFHEK 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 85.845 0.0089218 8089600 3733.2 2757.4 3013.1 3089.6 2951.6 4025.9 2775.6 2571.8 3181.3 3036.4 FALSE FALSE TRUE 3437.713281 2995.737369 3124.768137 3076.816054 2916.404098 3190.882959 2853.475866 3355.929981 2832.319349 3141.914674 1.094145971 0.953475088 0.994542647 0.979280589 0.928225111 1.015585492 0.908196486 1.068116206 0.901462848 1 11.61742829 -7.24653377 24.64913659 1.044457821 0.975695967 0 0.065343039 632.1078267 1045306.525 0.00834054 0.010192434 5.67E-08 7.24653377 -0.068761853 AGLVIGK(ac)GGETIK ddPTM_HeLa_Curcumin_4h_R1 2 AGLVIGKGGETIK 13 1 A0A087WTP3;Q92945;M0R0I5;M0QXW7;M0QYH3;Q96AE4;E9PEB5;Q96AE4-2;C9JSZ1 A0A087WTP3;Q96AE4 KHSRP;FUBP1 Far upstream element-binding protein 2;Far upstream element-binding protein 1 0 1 ; AGLVIGK(1)GGETIK;AGLVIGK(1)GGETIK 217.22 9.02E-28 4609000 3638.3 2970.7 3601.2 3222.2 3307.1 3911.1 2978.2 2958.2 3656.4 3198.8 FALSE TRUE FALSE 3350.324716 3227.474071 3734.66364 3208.86739 3267.664992 3099.893773 3061.760277 3860.141562 3255.302068 3309.958062 1.012195518 0.975080049 1.128311468 0.969458625 0.987222476 0.936535664 0.925014825 1.166220686 0.983487406 1 11.69259722 AGMS(ph)SNQSISSPVLDAVPR ddPTM_HeLa_Curcumin_4h_R1 1 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 AGMS(0.476)S(0.476)NQS(0.027)IS(0.01)S(0.01)PVLDAVPR 76.073 0.0074586 37929000 1685 1237.9 1541.4 1219.4 1702.8 1971.6 1143 1177.9 1697.9 1557.1 TRUE FALSE FALSE 1551.630472 1344.89856 1598.52564 1214.354446 1682.495222 1562.667935 1175.069504 1537.036288 1511.644618 1611.209109 0.963022405 0.834713851 0.992127981 0.753691398 1.044243862 0.969872828 0.729309124 0.953964497 0.938205109 1 10.65392803 -7.45694098 6.194952615 0.983990306 0.896855918 0.09519156 0.097058366 0.310001693 22.11159335 0.015566212 0.017573889 3.49E-08 7.45694098 -0.087134388 AGMSS(ph)NQS(ph)ISSPVLDAVPR ddPTM_HeLa_Curcumin_4h_R1 1 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 AGMS(0.439)S(0.54)NQS(0.575)IS(0.247)S(0.199)PVLDAVPR 79.332 0.0056296 11642000 1555.6 1196.4 1246.4 1146 1579.3 1520.4 1486.7 1264.9 1357.4 1129.8 TRUE FALSE FALSE 1432.472619 1299.811485 1292.59268 1141.258156 1560.467879 1205.051902 1528.412801 1650.562187 1208.496616 1169.060466 1.225319528 1.11184282 1.105667943 0.976218244 1.334805106 1.030786633 1.307385585 1.411870673 1.0337332 1 10.19113384 AGMSS(ph)NQSISSPVLDAVPR ddPTM_HeLa_Curcumin_4h_R1 1 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 AGMS(0.019)S(0.458)NQS(0.223)IS(0.185)S(0.114)PVLDAVPR 79.837 0.0053005 35731000 1356.5 1053.7 1258.7 1322.4 1188 1680.6 1127.2 967.89 1427.2 1283.4 TRUE FALSE FALSE 1249.131594 1144.777133 1305.348529 1316.928259 1173.833876 1332.024616 1158.826198 1262.995205 1270.639731 1327.998054 0.940612518 0.862032236 0.98294461 0.991664299 0.883912346 1.003032054 0.872611367 0.951052 0.956808428 1 10.37503732 -7.317552531 0.009419624 1.905944637 6.08E-07 0.045789951 0.049864631 1391.293459 11.44266171 1155.753146 1158.426951 4.81E-08 7.317552531 -1.90594403 AGMSSNQS(ph)IS(ph)SPVLDAVPRT(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 0 AGMS(0.136)S(0.251)NQS(0.685)IS(0.694)S(0.234)PVLDAVPRT(0.85)PS(0.15)R 68.412 0.0015972 3658600 1339.8 1290.2 1375.5 1611.4 1605.5 1479.9 1469.2 971.72 1209.2 1462.4 TRUE FALSE FALSE 1233.753416 1401.719139 1426.47724 1604.732454 1586.355461 1172.952058 1510.421798 1267.992955 1076.553785 1513.218291 0.815317541 0.926316545 0.942677767 1.060476511 1.048332201 0.775137378 0.998151956 0.837944507 0.711433236 1 10.5634044 -6.201636918 0.003767894 1.838730279 2.52E-05 0 0.116908037 116895.5139 169.2305544 40871.40271 41709.82515 6.29E-07 6.201636918 -1.838705082 AGMSSNQS(ph)ISS(ph)PVLDAVPR ddPTM_HeLa_Curcumin_4h_R1 2 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 AGMS(0.158)S(0.122)NQS(0.754)IS(0.213)S(0.753)PVLDAVPR;AGMS(0.057)S(0.086)NQS(0.684)IS(0.441)S(0.731)PVLDAVPR ; 87.157 0.0029617 17690000 4413.8 4024.1 4266.1 3866.7 4798.4 4826.9 3922.2 3550.4 4088.1 3655.5 TRUE FALSE FALSE 4064.443073 4371.925273 4424.205419 3850.70062 4741.182214 3825.74653 4032.246376 4632.900616 3639.645658 3782.528353 1.074530762 1.155820886 1.169642368 1.018022936 1.253442611 1.011425738 1.066018811 1.224815833 0.962225612 1 11.88513518 -8.124797708 0.853607793 1.010869506 1.123168273 0.331718753 0.078423241 0.486555728 0.761739245 0.023873209 0.016552162 7.50E-09 8.124797708 0.112298767 AGMSSNQSIS(ph)SPVLDAVPR ddPTM_HeLa_Curcumin_4h_R1 1 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 AGMSS(0.001)NQS(0.162)IS(0.815)S(0.023)PVLDAVPR 131.48 0.00018846 29221000 1938.8 1539.7 1725.5 1389.2 1745.2 1892.8 1766.1 1472.2 1791.8 1287.3 TRUE FALSE FALSE 1785.341934 1672.784807 1789.448548 1383.451858 1724.38963 1500.211944 1815.652013 1921.067003 1595.244023 1332.033579 1.340313009 1.255812791 1.343395974 1.038601339 1.294554174 1.126256851 1.363067749 1.442206137 1.197600457 1 10.37941474 -9.362048373 0.991362663 0.993649172 1.272875844 0.178020457 0.12592347 0.415507742 0.704105552 0.084900476 0.020139225 4.34E-10 9.362048373 0.279226671 AGMSSNQSIS(ph)SPVLDAVPRT(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 AGMS(0.013)S(0.013)NQS(0.008)IS(0.515)S(0.451)PVLDAVPRT(0.811)PS(0.189)R;AGMS(0.005)S(0.005)NQS(0.008)IS(0.518)S(0.465)PVLDAVPRT(0.816)PS(0.184)R ; 64.767 0.0054645 104677000 2795.3 2459.2 2508.35 2784.2 2901 3574.4 3160.6 2913.81 2607.36 2843.5 TRUE FALSE FALSE 2574.049055 2671.76229 2601.311658 2772.679718 2866.40747 2833.029148 3249.27793 3802.217255 2321.339131 2942.311413 0.874839095 0.90804878 0.884104805 0.942347471 0.974202614 0.962858362 1.104328357 1.292255211 0.788950864 1 11.52273423 -4.271053671 1.289409492 0.933445831 1.454028289 0.811185562 0.05774059 0.399697031 0.565571693 0.007553436 0.272536438 5.36E-05 4.271053671 0.520582458 AGMSSNQSISS(ph)PVLDAVPR ddPTM_HeLa_Curcumin_4h_R1 3 AGMSSNQSISSPVLDAVPR 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 AGMSSNQS(0.401)IS(0.145)S(0.454)PVLDAVPR;AGMS(0.014)S(0.123)NQS(0.274)IS(0.146)S(0.444)PVLDAVPR;AGMSSNQSIS(0.192)S(0.808)PVLDAVPR ;; 124.45 0.00020075 472572000 7803.7 8300.4 8158.5 7564.6 7709.1 9845.9 7930.9 6556.5 9027.5 9284.1 TRUE FALSE FALSE 7186.028911 9017.84959 8460.861187 7533.29969 7617.174017 7803.749354 8153.419709 8555.546668 8037.205836 9606.721784 0.748020925 0.938702066 0.880723037 0.784169653 0.792900449 0.812321781 0.848720291 0.890579207 0.83662315 1 13.22982849 -9.518007907 1.23589889 1.001202608 0.827799832 0 0.073086334 0.289505154 0.782730898 0.042905882 0.010019387 3.03E-10 9.518007907 -0.173402776 AGMSSNQSISS(ph)PVLDAVPRT(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 AGMS(0.03)S(0.086)NQS(0.038)IS(0.394)S(0.453)PVLDAVPRT(0.737)PS(0.263)R;AGMS(0.007)S(0.019)NQS(0.016)IS(0.449)S(0.509)PVLDAVPRT(0.803)PS(0.196)R ; 58.626 0.011182 88025000 2029.6 1864.78 1953.08 1875.42 2041.19 2802.3 2029.45 1821.91 2142.71 1820.4 TRUE FALSE FALSE 1868.955018 2025.963274 2025.462863 1867.660009 2016.850142 2221.071392 2086.390905 2377.401972 1907.660074 1883.658765 0.99219405 1.075546862 1.075281203 0.991506553 1.070708867 1.179126195 1.107626787 1.262119242 1.012741856 1 10.87932192 -1 0.313435973 0.99214869 3.37572011 0.758002549 0.041228462 15.82922558 0.202184193 0.013928924 21.77481863 0.1 1 2.383571421 AGMSSNQSISSPVLDAVPRTPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 AGMSSNQSISSPVLDAVPRTPSR 23 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 AGMSSNQSISSPVLDAVPRT(0.201)PS(0.799)R 87.352 0.00068145 27472000 839.88 814.93 677.77 813.42 687.06 1077.5 667.35 868.65 831.02 786.54 TRUE FALSE FALSE 773.4026118 885.3689179 702.8887524 810.0542836 678.8672582 854.0143541 686.0740449 1133.497386 739.8591851 813.8722065 0.950275247 1.087847589 0.863635282 0.995308941 0.834120213 1.049322421 0.84297515 1.392721581 0.909060635 1 9.668658471 -4.251085493 24.86759217 0.965913628 1.392721837 0.713589997 0.08382837 506.8785552 1217377.642 0.009927612 0.18562741 5.61E-05 4.251085493 0.426808208 AGMTSS(ph)PDATTGQTFG ddPTM_HeLa_Curcumin_4h_R1 2 AGMTSSPDATTGQTFG 16 0 Q9UQR1;G5E9X2;Q9UQR1-2 Q9UQR1 ZNF148 Zinc finger protein 148 1 0 AGMT(0.015)S(0.089)S(0.895)PDAT(0.001)TGQTFG;AGMT(0.009)S(0.069)S(0.922)PDATTGQTFG ; 186.76 3.70E-06 40009000 6837.7 3751.2 5406 5942.5 5811.9 7275.1 4793.5 3065.9 6666.5 4589 TRUE FALSE FALSE 6296.48883 4075.437013 5606.351116 5917.91151 5742.596888 5766.162253 4927.992709 4000.678796 5935.201629 4748.467408 1.326004432 0.858263659 1.180665388 1.24627822 1.209357966 1.214320697 1.037806999 0.842520007 1.24991942 1 12.21324624 -4.390247513 2.941520908 1.151376218 0.828550953 0.362046721 0.129372832 0.309923313 4.238314399 0.020778576 0.198675433 4.07E-05 4.390247513 -0.322825265 AGNLGGGVVTIER ddPTM_HeLa_Curcumin_4h_R1 2 AGNLGGGVVTIER 13 0 K7ERI7;P35268;K7EP65;K7EKS7;K7ELC4;K7EMH1;K7EJT5 K7ERI7 RPL22 60S ribosomal protein L22 0 0 ; ; 149.49 0.00025507 30553000 4781.5 4841.8 4670.9 4722.5 4293.4 6030.6 4239.6 4530.7 5270.7 4330.2 FALSE FALSE TRUE 4403.03923 5260.303617 4844.007663 4702.959546 4242.204009 4779.785581 4358.551766 5912.089573 4692.517397 4480.674128 0.982673389 1.173998257 1.081089034 1.049609816 0.946778071 1.066755904 0.972744645 1.319464305 1.04727933 1 12.12950009 -4.256575686 24.71139246 1.014654653 1.319464453 0.617711242 0.065119836 205.827186 1045721.969 0.009269427 0.100640547 5.54E-05 4.256575686 0.3048098 AGNNMLLVGVHGPR ddPTM_HeLa_Curcumin_4h_R1 1 AGNNMLLVGVHGPR 14 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 108.68 0.0004237 4535700 1662.3 1353.6 1569.8 1574.9 1793.1 1969 1589 1699.4 1539.4 1792.2 FALSE FALSE TRUE 1530.727201 1470.599152 1627.978169 1568.383481 1771.718454 1560.607205 1633.583063 2217.539237 1370.531671 1854.478817 0.825421777 0.792998625 0.877862909 0.845727364 0.955372711 0.841534123 0.880885265 1.195774908 0.739038731 1 10.85679807 -4.259656164 24.4108825 0.895903842 1.195775048 0.597551567 0.077821081 65.00734042 889795.0358 0.010981987 0.094595204 5.50E-05 4.259656164 0.299871206 AGNSDS(ph)EEDDANGRVELILEPK ddPTM_HeLa_Curcumin_4h_R1 1 AGNSDSEEDDANGRVELILEPK 22 1 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1-5;A0A0A0MT65;Q641Q2;F8W7U3;E7ESD2;Q641Q2-2;A0A087WYF6 A0A0A0MR88;Q641Q2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 0 AGNS(0.418)DS(0.582)EEDDANGRVELILEPK 75.297 0.00065617 12971000 1779.6 1226.6 1177.1 1407.9 1496.7 2131.4 1537.9 936.91 2007.2 1699.7 TRUE FALSE FALSE 1638.742782 1332.621838 1220.724361 1402.074483 1478.85283 1689.323614 1581.049335 1222.569546 1787.015182 1758.764448 0.931757964 0.75770342 0.694080644 0.797192873 0.84084758 0.960517263 0.898954568 0.695129781 1.016062829 1 10.78034656 -7.444519344 3.828873207 0.971557472 0.812831031 0.504041948 0.080360114 0.167794133 4.463243535 0.015219205 0.017023595 3.59E-08 7.444519344 -0.158726442 AGPDAVTLQAVTHDNEWEMLS(ph)PQPVQK ddPTM_HeLa_Curcumin_4h_R1 1 AGPDAVTLQAVTHDNEWEMLSPQPVQK 27 0 E9PDC2;A0A088AWP5;Q8WUY3-4;Q8WUY3;Q8WUY3-2;Q8WUY3-3;H7BZH9 E9PDC2 PRUNE2 Protein prune homolog 2 1 0 AGPDAVTLQAVT(0.005)HDNEWEMLS(0.995)PQPVQK 84.948 2.10E-05 4896800 1524.3 1218 1238.7 1317.5 1286.8 1208.2 902.6 951.45 1418.5 1291.3 TRUE FALSE FALSE 1403.650047 1323.278493 1284.607312 1312.048534 1271.45575 957.6057008 927.9245268 1241.542725 1262.894099 1336.172579 1.050500563 0.990349984 0.961408228 0.981945412 0.951565517 0.716678157 0.694464578 0.92917842 0.945157923 1 10.38389064 -5.418078793 3.768019329 1.012765572 0.772544092 0.650129588 0.066869622 0.088146377 2.248206056 0.009092159 0.021230252 3.82E-06 5.418078793 -0.240221479 AGPDLPSLPSHALEDEGWAAAAPS(ph)PGS(ph)AR ddPTM_HeLa_Curcumin_4h_R1 1 AGPDLPSLPSHALEDEGWAAAAPSPGSAR 29 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 2 0 AGPDLPS(0.044)LPS(0.444)HALEDEGWAAAAPS(0.566)PGS(0.946)AR 59.399 0.0052713 25337000 2380.2 2364.9 2545.8 2113.8 2473.2 3398 1907.3 939.52 3006.7 2411.1 TRUE FALSE FALSE 2191.804658 2569.311418 2640.149588 2105.053656 2443.708705 2693.216497 1960.813705 1225.975323 2676.872532 2494.885546 0.878519122 1.029831378 1.058224732 0.843747586 0.979487299 1.07949501 0.78593333 0.491395417 1.072944022 1 11.28475792 -4.392977354 3.062110712 0.958698249 0.475131128 0.774737414 0.082084391 0.102525481 1.537310037 0.010971446 0.099413129 4.05E-05 4.392977354 -0.483567121 AGPDLPSLPSHALEDEGWAAAAPS(ph)PGSAR ddPTM_HeLa_Curcumin_4h_R1 4 AGPDLPSLPSHALEDEGWAAAAPSPGSAR 29 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 0 AGPDLPSLPSHALEDEGWAAAAPS(0.634)PGS(0.366)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.947)PGS(0.053)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.5)PGS(0.5)AR;AGPDLPSLPSHALEDEGWAAAAPS(0.783)PGS(0.217)AR ;;; 170.34 2.04E-16 296171000 13049.5 10392.79 11389.5 11454 12550.2 18916.8 12717.1 4917.09 14853.4 11374.5 TRUE FALSE FALSE 12016.61831 11291.09646 11811.60489 11406.60638 12400.54706 14993.24244 13073.9076 6416.288106 13224.01918 11769.76303 1.020973683 0.959330823 1.00355503 0.969144948 1.053593605 1.273878022 1.110804658 0.545150152 1.12355866 1 13.52279765 -4.255510851 24.96250657 1.029132501 0.545149937 0.726596515 0.092803895 270.5224637 1139021.365 0.01286769 0.15543724 5.55E-05 4.255510851 -0.483982564 AGPGDRDPPTRGEESR ddPTM_HeLa_Curcumin_4h_R1 1 AGPGDRDPPTRGEESR 16 2 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 0 0 53.946 0.020217 2223700 391.86 447.18 263.03 434.03 451.25 336.28 423.11 234.47 606.42 388.75 FALSE FALSE TRUE 360.8438675 485.8322466 272.7781232 432.2340989 445.8691385 266.5317373 434.9813279 305.9588236 539.8972432 402.2590336 0.89704354 1.207759692 0.678115593 1.074516823 1.108412991 0.662587326 1.081346326 0.760601498 1.342163129 1 8.65198101 -4.231906535 22.68084329 0.955273201 0.760600423 0.066835824 0.208535625 5041.151037 3871317.044 0.02063171 2.497025985 5.86E-05 4.231906535 -0.194672777 AGPLSGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AGPLSGKK 8 1 P17844-2;P17844;J3KTA4;J3QRQ7;J3QR02;J3KRX8;J3KTQ4;X6RLV5;J3QKN9 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 1 ; AGPLSGK(1)K;AGPLSGK(1)K 79.713 0.014737 113434000 8937.8 6100 7440.2 6445 7537.1 9050.2 7193 8585.9 7057.4 7709.9 FALSE TRUE FALSE 8230.363699 6627.256819 7715.940357 6418.332298 7447.225005 7173.086503 7394.816221 11203.70139 6283.220877 7977.818451 1.031655928 0.830710408 0.967174222 0.804522231 0.933491411 0.899128822 0.926922099 1.404356524 0.787586345 1 12.96177858 -4.258131766 24.91295086 0.96817802 1.404356694 0.675353368 0.095399171 134.1365369 1010266.356 0.01231116 0.118760291 5.52E-05 4.258131766 0.436178674 AGQAVDDFIEK ddPTM_HeLa_Curcumin_4h_R1 3 AGQAVDDFIEK 11 0 P52209-2;P52209;K7EMN2;K7EM49;K7EPF6 P52209-2 PGD "6-phosphogluconate dehydrogenase, decarboxylating" 0 0 ;; ;; 180.88 1.14E-11 14934000 9445.3 8180.9 8330.7 9380.2 8070.6 8067.3 6669.9 6667.7 9846.5 8682.9 FALSE FALSE TRUE 8697.694538 8888.020543 8639.44307 9341.387218 7974.363366 6394.051043 6857.039443 8700.651036 8766.363585 8984.630129 0.968063728 0.989247238 0.961580271 1.039707488 0.88755611 0.711665472 0.763196631 0.96839279 0.975706675 1 13.1332434 -5.543605746 5.874041523 0.985936658 0.807300934 0.602109982 0.064212686 0.076057962 8.647801901 0.008759621 0.018118624 2.86E-06 5.543605746 -0.178635724 AGQSAAGAAPGGGVDTR ddPTM_HeLa_Curcumin_4h_R1 2 AGQSAAGAAPGGGVDTR 17 0 P21333-2;P21333 P21333-2 FLNA Filamin-A 0 0 ; ; 258.96 8.68E-62 17038300 6423 5760.5 5633.1 6321.5 5573.9 6874.6 5791.3 5410.9 7001.5 5688.6 FALSE FALSE TRUE 5914.612772 6258.411952 5841.867641 6295.343308 5507.434883 5448.730467 5953.788292 7060.658501 6233.452967 5886.278427 1.004813627 1.06322051 0.992455201 1.069494654 0.935639547 0.925666452 1.011469023 1.199511472 1.058980312 1 12.52314007 -4.265013893 5.622716496 1.000864081 1.205870972 0.601424295 0.04689034 0.063095403 8.104568036 0.005828572 0.049486807 5.43E-05 4.265013893 0.205006891 AGS(ph)FTGTSDPEAAPAR ddPTM_HeLa_Curcumin_4h_R1 2 AGSFTGTSDPEAAPAR 16 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 0 AGS(0.959)FT(0.003)GT(0.019)S(0.019)DPEAAPAR;AGS(0.832)FT(0.093)GT(0.007)S(0.068)DPEAAPAR ; 127.66 0.00048369 17554200 2024.22 1856.37 2573.2 2616.1 2141.66 3533 2720.3 2087.02 3029.4 2248.5 TRUE FALSE FALSE 1864.000851 2016.826351 2668.565056 2605.275271 2116.122103 2800.215975 2796.624297 2723.342791 2697.082399 2326.635208 0.80115733 0.866842531 1.14696324 1.119760959 0.909520365 1.203547495 1.202003772 1.170506997 1.159220143 1 11.18402931 -6.760016343 24.99980412 0.900533981 1.122351886 0.271352635 0.1220609 24.15158293 424288.9641 0.017423147 0.023886378 1.74E-07 6.760016343 0.221817905 AGS(ph)ISTLDSLDFAR ddPTM_HeLa_Curcumin_4h_R1 2 AGSISTLDSLDFAR 14 0 A0A075B785;A0A2R8Y566;Q9P260;Q9P260-2 A0A075B785 KIAA1468 LisH domain and HEAT repeat-containing protein KIAA1468 1 0 AGS(0.983)IS(0.004)T(0.013)LDSLDFAR;AGS(0.956)IS(0.044)TLDSLDFAR ; 214.48 9.12E-14 19655400 3698.6 2975.9 2911.01 2944 3167.4 4249.3 3868.5 3340.5 3094 2519.54 TRUE FALSE FALSE 3405.851907 3233.123536 3018.894591 2931.818508 3129.630824 3367.947281 3977.039698 4359.003072 2754.595941 2607.093827 1.306378724 1.2401255 1.157953948 1.124554275 1.200428918 1.291839689 1.525468572 1.671977827 1.056577217 1 11.34822679 -1 0.465360385 1.138601285 15.62457792 0.812309207 0.085004958 34.77327608 0.362982293 0.025018625 486.9410404 0.1 1 14.48597663 RLAT(ph)LPT(ph)KEQKT(ph)QR ddPTM_HeLa_Curcumin_4h_R1 1 RLATLPTKEQKTQR 14 3 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;F8W860;Q9UBF8-3;E9PL47 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 3 0 RLAT(1)LPT(1)KEQKT(1)QR 55.688 0.014186 38037000 2162.4 1410.7 1661.3 2223.8 1576.7 241.25 486.79 554.14 1695.8 1980.9 TRUE FALSE FALSE 1991.243758 1532.634622 1722.869239 2214.598505 1557.898882 191.2120306 500.4480173 723.0947351 1509.774983 2049.736128 0.971463464 0.74772289 0.840532211 1.080431025 0.760048506 0.093286169 0.244152411 0.352774548 0.736570411 1 11.00122248 -5.405201188 4.120938209 0.959099466 0.234826775 0.840215605 0.128216968 0.050219516 1.442417295 0.016055166 0.03721364 3.93E-06 5.405201188 -0.724272691 down AGS(ph)PLCNSNLQDSEEDIEPSYSLFR ddPTM_HeLa_Curcumin_4h_R1 1 AGSPLCNSNLQDSEEDIEPSYSLFR 25 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 0 AGS(0.999)PLCNS(0.001)NLQDSEEDIEPSYSLFR 198.06 3.35E-18 14805000 2383.9 1922.8 2227 1584.5 1932.4 2062.7 1342.5 1232.1 2284.8 1976.8 TRUE FALSE FALSE 2195.2118 2088.998264 2309.534579 1577.943759 1909.357392 1634.872769 1380.166937 1607.761618 2034.163156 2045.493653 1.073194139 1.021268514 1.129084207 0.771424422 0.933445767 0.79925585 0.67473538 0.786001763 0.994460752 1 10.99823335 -5.781625393 1.096394221 1.039738323 0.740323425 0.689113042 0.079695786 0.197545498 0.463372825 0.012551621 0.036263491 1.65E-06 5.781625393 -0.299414898 AGS(ph)PSPQPSGELPR ddPTM_HeLa_Curcumin_4h_R1 3 AGSPSPQPSGELPR 14 0 Q92619 Q92619 HMHA1 Minor histocompatibility protein HA-1;Minor histocompatibility antigen HA-1 1 0 AGS(0.896)PS(0.104)PQPSGELPR;AGS(1)PSPQPSGELPR;AGS(0.998)PS(0.002)PQPSGELPR ;; 182.7 9.26E-05 296316000 2684.75 2222.31 2243.06 2543.17 2719.45 2523.19 1737.28 1334.32 2851.23 2345.07 TRUE FALSE FALSE 2472.249205 2414.396574 2326.189777 2532.647036 2687.022335 1999.851952 1786.023401 1741.148026 2538.457202 2426.561008 1.018828373 0.994986966 0.958636428 1.043718674 1.107337638 0.824150699 0.736030702 0.717537297 1.046113077 1 11.24469742 -5.065334811 4.204247974 1.012221783 0.734704156 0.907306288 0.039402626 0.044248132 1.529786963 0.00548944 0.015397132 8.60E-06 5.065334811 -0.277517627 AGS(ph)SPAQGAQNEPPR ddPTM_HeLa_Curcumin_4h_R1 4 AGSSPAQGAQNEPPR 15 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 0 AGS(0.591)S(0.409)PAQGAQNEPPR;AGS(0.5)S(0.5)PAQGAQNEPPR;AGS(0.584)S(0.416)PAQGAQNEPPR;AGS(0.619)S(0.381)PAQGAQNEPPR ;;; 191.15 2.49E-06 33378300 6687.1 6251.4 5544.76 6636.7 6403.8 6036.05 4586.48 3365.7 6920.8 6315.2 TRUE FALSE FALSE 6157.808979 6791.74316 5750.253683 6609.239094 6327.438867 4784.10519 4715.164285 4391.886436 6161.605555 6534.65273 0.94233148 1.039342631 0.879963163 1.011413975 0.968289996 0.732113149 0.721563101 0.672091788 0.942912471 1 12.67389485 -5.237362719 4.327864398 0.973404503 0.704349363 0.885078387 0.043105953 0.04552687 2.085488663 0.00585624 0.015047404 5.79E-06 5.237362719 -0.26905514 AGS(ph)ST(ph)PGDAPPAVAEVQGR ddPTM_HeLa_Curcumin_4h_R1 2 AGSSTPGDAPPAVAEVQGR 19 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 2 0 AGS(0.588)S(0.414)T(0.997)PGDAPPAVAEVQGR;AGS(0.69)S(0.32)T(0.99)PGDAPPAVAEVQGR ; 174.87 7.14E-06 30051000 4938.7 4474.2 4038.3 4240.4 3132.1 2783.8 2096.24 2731.6 5411.7 5173 TRUE FALSE FALSE 4547.796684 4860.929911 4187.96295 4222.854348 3094.751753 2206.4085 2155.054853 3564.452265 4818.050049 5352.761365 0.849616931 0.908116312 0.782392987 0.788911379 0.578159858 0.41220005 0.402606189 0.665909056 0.90010552 1 12.38606762 -5.974927762 1.112589424 0.927668804 0.474257772 0.814199582 0.085061097 0.147563091 0.360481312 0.015493989 0.038108619 1.06E-06 5.974927762 -0.453411032 AGSCCLS(ph)PGGR ddPTM_HeLa_Curcumin_4h_R1 1 AGSCCLSPGGR 11 0 E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;W0Z7M9;B0QY83;A0A499FIJ6;Q969V6 E7ER32 MKL1;mkl1 MKL/myocardin-like protein 1 1 0 AGSCCLS(1)PGGR 114.76 0.0049572 72788000 3502.9 2264.6 2813.2 2821 2804.7 3294.6 2004.2 1088 3093.8 2642 TRUE FALSE FALSE 3225.641769 2460.341933 2917.459667 2809.327449 2771.255784 2611.262822 2060.432458 1419.726191 2754.41788 2733.809303 1.179907379 0.899968381 1.067177459 1.02762378 1.013697547 0.955173727 0.75368551 0.519321589 1.007538411 1 11.4166969 -4.040840803 0.829244699 1.070005339 2.67E-16 0.836474001 0.071021815 0.965138288 0.378740909 0.013347144 1.027383483 9.10E-05 4.040840803 -1.070005339 AGSIS(ph)SEEVDGSQGNMMR ddPTM_HeLa_Curcumin_4h_R1 1 AGSISSEEVDGSQGNMMR 18 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 AGS(0.189)IS(0.702)S(0.109)EEVDGSQGNMMR 181.86 5.83E-07 3820100 735.94 806.45 863.35 800.52 837.08 1018.6 695.58 635.37 812.78 819.49 TRUE FALSE FALSE 677.6895724 876.1559445 895.3465105 797.2076603 827.0983677 807.330878 715.0961027 829.0913881 723.6200675 847.9672165 0.799193128 1.03324271 1.055873969 0.940139719 0.975389557 0.952077937 0.843306308 0.977739908 0.853358542 1 9.727864679 -7.235485434 24.98941674 0.905174513 0.965388368 0.206689993 0.071883214 1477.812508 1422893.86 0.015272259 0.018701158 5.81E-08 7.235485434 0.060213855 AGSNEDPILAPS(ph)GTPPPTIPPDETFGGR ddPTM_HeLa_Curcumin_4h_R1 1 AGSNEDPILAPSGTPPPTIPPDETFGGR 28 0 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 "Proline-, glutamic acid- and leucine-rich protein 1" 1 0 AGSNEDPILAPS(0.5)GT(0.5)PPPTIPPDETFGGR 115.92 5.45E-11 49032000 3838.7 2760.1 3019.6 3193.9 3505.5 3973.6 2841 1736.7 3908 3195 TRUE FALSE FALSE 3534.862844 2998.670745 3131.509032 3180.684488 3463.699202 3149.430568 2920.710814 2266.211835 3479.302177 3306.026012 1.069218098 0.907031806 0.94721246 0.962086952 1.047692665 0.95263333 0.883450645 0.68547913 1.052412221 1 11.69088236 -3.646043142 0.897803532 1.015103228 2.56E-13 0.776275095 0.050312832 2.003799436 0.55610629 0.008818185 2.600723125 0.000225921 3.646043142 -1.015103228 KQS(ph)AGPNS(ph)PTGGGGGGGSGGTR ddPTM_HeLa_Curcumin_4h_R1 2 KQSAGPNSPTGGGGGGGSGGTR 22 1 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 2 0 KQS(1)AGPNS(0.883)PT(0.116)GGGGGGGSGGTR;KQS(0.999)AGPNS(0.918)PT(0.079)GGGGGGGS(0.002)GGT(0.002)R ; 85.525 0.00023674 7041600 6870 6607 6038.9 5139 5578 2886.2 2262.54 2324.86 5112.4 5876.3 TRUE FALSE FALSE 6326.232251 7178.07964 6262.706946 5117.73618 5511.485993 2287.569586 2326.020783 3033.699112 4551.582511 6080.500988 1.040412996 1.180507931 1.029965616 0.841663572 0.906419718 0.376213998 0.382537687 0.498922559 0.748553864 1 12.56997448 -5.398410521 2.134569468 1.025217825 0.403004448 0.794004888 0.124767234 0.067637319 0.597048113 0.013139215 0.035870028 4.00E-06 5.398410521 -0.622213377 down AGSNEDPILAPSGT(ph)PPPTIPPDETFGGR ddPTM_HeLa_Curcumin_4h_R1 2 AGSNEDPILAPSGTPPPTIPPDETFGGR 28 0 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 "Proline-, glutamic acid- and leucine-rich protein 1" 1 0 AGSNEDPILAPS(0.059)GT(0.941)PPPTIPPDETFGGR;AGSNEDPILAPS(0.052)GT(0.948)PPPTIPPDETFGGR ; 107.43 1.92E-09 19071000 6523 5660.3 5794 6577 6191.7 7058.5 5469.9 4703.8 7476.4 6201.6 TRUE FALSE FALSE 6006.697667 6149.55111 6008.730737 6549.786117 6117.868021 5594.487534 5623.370673 6137.966966 6656.257625 6417.105138 0.936044764 0.958306117 0.936361585 1.020676142 0.953368831 0.871808614 0.876309574 0.95650092 1.037267971 1 12.64770691 -11.47144005 0.010370883 2.004897856 1.11E-06 0.377594166 0.040948864 6193.781855 7.758110958 826.5233852 679.5917607 3.38E-12 11.47144005 -2.004896744 ASEAAS(ph)PLPDSPGDK ddPTM_HeLa_Curcumin_4h_R1 2 ASEAASPLPDSPGDK 15 0 Q68CZ2;Q68CZ2-2 Q68CZ2 TNS3 Tensin-3 1 0 ASEAAS(1)PLPDSPGDK;AS(0.011)EAAS(0.989)PLPDSPGDK ; 182.57 4.23E-05 93650000 17159.5 14920.2 15511.8 14415.6 13021.9 7968.5 4758.1 5396.8 15579.1 14929.3 TRUE FALSE FALSE 15801.30747 16209.8356 16086.68095 14355.95207 12866.62235 6315.743276 4891.59948 7042.259476 13870.11171 15448.09206 1.022864662 1.049309878 1.041337719 0.929302597 0.832893945 0.40883646 0.316647484 0.45586597 0.897852735 1 13.91514105 -5.385296693 2.160297766 1.01294694 0.367309795 0.95546199 0.057498619 0.031858581 0.287667534 0.006450296 0.017691865 4.12E-06 5.385296693 -0.645637145 down AGSPS(ph)RDVGPSLGLK ddPTM_HeLa_Curcumin_4h_R1 2 AGSPSRDVGPSLGLK 15 1 F5GZI3;Q5VWV2;Q8TEW0-4;Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-3;Q8TEW0-7;Q8TEW0-6;Q8TEW0-8;Q5VWU8;Q8TEW0-9;Q8TEW0-10 F5GZI3;Q5VWV2 PARD3 Partitioning defective 3 homolog 1 0 AGS(0.065)PS(0.915)RDVGPS(0.02)LGLK;AGS(0.01)PS(0.99)RDVGPSLGLK ; 122.1 0.00050954 121884000 12841.4 9987.1 10534.3 11773.5 11882.5 13055.8 9316.9 7074.6 13155.6 10031.7 TRUE FALSE FALSE 11824.98964 10850.34042 10924.71042 11724.78438 11740.80895 10347.87991 9578.307139 9231.612973 11712.46359 10380.30083 1.139176006 1.045281886 1.052446418 1.1295226 1.131066348 0.996876688 0.922738878 0.889339637 1.128335661 1 13.34156063 -4.900229213 2.908771709 1.073143049 0.901473966 0.710831725 0.046232386 0.140311562 2.348627768 0.008313904 0.030823476 1.26E-05 4.900229213 -0.171669083 AGSQEAEVGS(ph)DGER ddPTM_HeLa_Curcumin_4h_R1 1 AGSQEAEVGSDGER 14 0 J3KN78;Q9UK96 J3KN78 FBXO10 F-box only protein 10 1 0 AGSQEAEVGS(1)DGER 112.34 0.0026164 5393200 773.51 815.8 806.23 952.05 889.9 800.36 735.14 268.38 1178 677.44 TRUE FALSE FALSE 712.2858673 886.3141169 836.109593 948.1106694 879.2885237 634.3563141 755.7660499 350.2078265 1048.776347 700.9809896 1.016127224 1.264391089 1.192770711 1.352548334 1.254368573 0.904955089 1.078154845 0.499596753 1.496155192 1 9.453231509 -4.261143747 24.6156384 1.073348169 0.499596539 0.457830096 0.194236856 11.67081318 971167.4012 0.022086076 0.172593934 5.48E-05 4.261143747 -0.57375163 AGSS(ph)PAQGAQNEPPR ddPTM_HeLa_Curcumin_4h_R1 1 AGSSPAQGAQNEPPR 15 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 0 AGS(0.237)S(0.763)PAQGAQNEPPR 94.569 0.0058232 5942100 1533.4 1514.4 1376.5 1634.6 1205.2 1366.6 1197.3 972.91 1530.4 1579 TRUE FALSE FALSE 1412.029772 1645.297988 1427.514301 1627.836458 1190.828777 1083.151755 1230.893016 1269.54578 1362.518949 1633.870132 0.864223994 1.006994348 0.873701203 0.996307127 0.728839308 0.66293626 0.753360375 0.777017558 0.833921205 1 10.6740776 -5.751504758 24.99795573 0.938911155 0.727339733 0.702718839 0.063095083 81.39840503 204816.9283 0.0091647 0.018155719 1.77E-06 5.751504758 -0.211571422 AGSS(ph)PCLGSSSAASS(ph)PPPPASR ddPTM_HeLa_Curcumin_4h_R1 1 AGSSPCLGSSSAASSPPPPASR 22 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 2 0 AGS(0.235)S(0.765)PCLGSSSAAS(0.001)S(0.999)PPPPASR 210.98 5.14E-55 0 628.2 577.4 594.91 737.39 881.74 885.53 514.43 244.5 959.81 638.62 TRUE FALSE FALSE 578.4773071 627.3078832 616.9578879 734.3388756 871.2258264 701.861096 528.8635213 319.0469245 854.5212443 660.8119975 0.87540376 0.949298568 0.933636027 1.111267468 1.318417083 1.062119179 0.800323728 0.48281043 1.293138211 1 9.36809607 -4.393934615 2.924108778 0.984983142 0.461404098 0.534622027 0.157110334 0.184161603 2.493365202 0.019971316 0.190242033 4.04E-05 4.393934615 -0.523579044 AGSS(ph)TPGDAPPAVAEVQGR ddPTM_HeLa_Curcumin_4h_R1 1 AGSSTPGDAPPAVAEVQGR 19 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 AGS(0.068)S(0.466)T(0.466)PGDAPPAVAEVQGR 274.81 1.56E-68 72773000 3226.8 2468 3006.2 2812.5 2625.8 3511.2 2583.9 5597 3098.3 2811.2 TRUE FALSE FALSE 2971.395375 2681.322923 3117.612417 2800.86262 2594.48905 2782.937541 2656.39728 7303.499535 2758.424242 2908.888991 1.021488061 0.921768734 1.071753658 0.962863357 0.891917518 0.956701184 0.91319995 2.510752235 0.948274152 1 11.50625253 -4.259704746 24.999978 0.989106701 2.510752743 0.985683704 0.055808511 12.27949727 176960.1483 0.007785993 0.066821417 5.50E-05 4.259704746 1.521646041 AGSSPCLGSSSAASS(ph)PPPPASR ddPTM_HeLa_Curcumin_4h_R1 1 AGSSPCLGSSSAASSPPPPASR 22 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 0 AGSSPCLGSSSAAS(0.063)S(0.937)PPPPASR 178.1 6.28E-10 19641000 1255.4 1193.8 992.42 1028.2 1098 1329.8 987.21 694 981.57 1049.6 TRUE FALSE FALSE 1156.033765 1296.986753 1029.199958 1023.945581 1084.907067 1053.98449 1014.908456 905.5974052 873.8942268 1086.073522 1.064415753 1.194197931 0.947633781 0.942795824 0.998925989 0.970454089 0.934474909 0.83382698 0.804636343 1 10.08490605 -6.57167933 24.9999837 1.04485502 0.941785117 0.101553998 0.099095571 93.24852851 47769.80007 0.010639301 0.015046246 2.68E-07 6.57167933 -0.103069903 GYYS(ph)PYSVSGSGST(ph)AGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 3 0 GY(0.001)Y(0.011)S(0.978)PY(0.031)S(0.117)VS(0.008)GS(0.01)GS(0.127)T(0.726)AGS(0.99)R 83.891 0.015889 17200000 1853.9 1525.1 2047 1956.8 2007.4 3059.8 4206.9 4019.1 1939.1 1951.3 TRUE FALSE FALSE 1707.161859 1656.922848 2122.863621 1948.70328 1983.463066 2425.162989 4324.934292 5244.505088 1726.385581 2019.10753 0.845503191 0.8206214 1.051387105 0.965131005 0.982346426 1.201106406 2.142002953 2.597437239 0.855024092 1 10.97950203 -4.696398077 2.006281746 0.930988555 2.631649223 0.984515823 0.072260642 0.034577862 0.247124736 0.01191813 0.078208258 2.01E-05 4.696398077 1.700660669 up AGT(ph)EDEEEEEEGRR ddPTM_HeLa_Curcumin_4h_R1 2 AGTEDEEEEEEGRR 14 1 F8WBH7;O95456-2;O95456 F8WBH7 PSMG1 Proteasome assembly chaperone 1 1 0 AGT(1)EDEEEEEEGRR;AGT(1)EDEEEEEEGRR ; 130.01 0.00057155 35293000 6102.1 5654.9 6402.6 5587.7 6799.5 5907.3 4956.7 3584 5910.6 5657.4 TRUE FALSE FALSE 5619.112346 6143.684358 6639.885988 5564.579578 6718.420403 4682.059391 5095.771662 4676.745101 5262.221968 5853.994229 0.959876646 1.049485893 1.13424881 0.950561166 1.147664337 0.799805946 0.870477739 0.79889814 0.898911369 1 12.51520561 -5.234640224 24.98730865 1.0049607 0.82780229 0.576095759 0.076658752 408.7882826 381150.2994 0.009785372 0.024940869 5.83E-06 5.234640224 -0.177158409 VTGPQATT(ph)GTPLVTMRPAS(ph)QAGK ddPTM_HeLa_Curcumin_4h_R1 1 VTGPQATTGTPLVTMRPASQAGK 23 1 P51610-2;P51610;A6NEM2;P51610-4 P51610-2 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 2 0 VT(0.186)GPQAT(0.34)T(0.398)GT(0.076)PLVT(0.002)MRPAS(0.998)QAGK 59.302 0.010423 134570000 7495.5 4949.5 6669.6 7839.4 6209 309.84 1921.2 2471.9 7795 7600.1 TRUE FALSE FALSE 6902.223266 5377.312725 6916.781243 7806.96264 6134.96173 245.5756914 1975.103701 3225.570931 6939.908002 7864.202909 0.877676142 0.683770852 0.879527312 0.992721415 0.78011234 0.031227029 0.251151162 0.41015866 0.882468075 1 12.94108483 -5.385174009 4.906264247 0.916048507 0.236467833 0.853778822 0.121388487 0.059183104 2.117668762 0.018404419 0.042088077 4.12E-06 5.385174009 -0.679580674 down GAES(ph)PFEEK ddPTM_HeLa_Curcumin_4h_R1 7 GAESPFEEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK;GAES(1)PFEEK ;;;;;; 146.71 0.001925 6338371000 64287 61147.5 53256.4 53756.5 43389.4 28425.2 16059.69 12271.83 61618.1 50892.5 TRUE FALSE FALSE 59198.61611 66432.81743 55230.12903 53534.06985 42872.00974 22529.4931 16510.28168 16013.45447 54858.74859 52661.01059 1.124145083 1.261518089 1.048785969 1.016578855 0.814112932 0.427821131 0.313520031 0.30408559 1.041733685 1 15.68444759 -5.366081694 1.692868484 1.077145179 0.294954285 0.960390431 0.067026348 0.059825944 0.327768276 0.012134457 0.03811114 4.30E-06 5.366081694 -0.782190894 down AGTEDEEEEEEGRR ddPTM_HeLa_Curcumin_4h_R1 3 AGTEDEEEEEEGRR 14 1 F8WBH7;O95456-2;O95456 F8WBH7 PSMG1 Proteasome assembly chaperone 1 0 0 ;; ;; 220.31 6.08E-14 10260670 4421.57 3967.7 4121.06 4000.18 4944.28 4641.71 4047.86 3854.69 4280.93 3698.18 FALSE FALSE TRUE 4071.598069 4310.650308 4273.790109 3983.628315 4885.32269 3678.967023 4161.432057 5029.967236 3811.322689 3826.69148 1.063999565 1.126469257 1.116836863 1.041011102 1.276643993 0.961396298 1.087475193 1.314442845 0.995983792 1 11.90188188 -1.000000002 0.075355842 0.875627738 1.665373953 0.289489807 0.093526305 200.4928919 1.118786992 1.93958088 16.69776252 0.099999999 1.000000002 0.789746215 AGTEDEEEEEEGRRETPEDR ddPTM_HeLa_Curcumin_4h_R1 2 AGTEDEEEEEEGRRETPEDR 20 2 F8WBH7;O95456-2;O95456 F8WBH7 PSMG1 Proteasome assembly chaperone 1 0 0 ; ; 66.068 0.0031796 20645200 4544.4 3959.8 3906.4 4532 3764.7 5393.1 3679 3859.4 5379.7 4787.9 FALSE FALSE TRUE 4184.705945 4302.067467 4051.17462 4513.247785 3719.808411 4274.510267 3782.222838 5036.113294 4789.560369 4954.279169 0.844664946 0.868353866 0.817712221 0.910979707 0.750827373 0.862791563 0.763425457 1.016517867 0.966752217 1 12.27445945 -9.191400776 0.673091503 1.014279935 0.84709311 0.333311746 0.071814669 0.689454874 0.492264542 0.066863559 0.013885041 6.44E-10 9.191400776 -0.167186824 AGTEPSDAIR ddPTM_HeLa_Curcumin_4h_R1 2 AGTEPSDAIR 10 0 Q15645 Q15645 TRIP13 Pachytene checkpoint protein 2 homolog 0 0 ; ; 106.68 0.0063595 3848200 2255.1 2064.8 2175.9 2077.4 2030.91 2073.1 1751.65 1817.98 2433.83 2224.46 FALSE FALSE TRUE 2076.606455 2243.272111 2256.540768 2068.804269 2006.692725 1643.115691 1800.796585 2372.273733 2166.844938 2301.759819 0.902182077 0.974590004 0.980354574 0.898792416 0.871808043 0.713851931 0.782356425 1.030634783 0.941386204 1 11.16852159 -5.882735611 2.589910567 0.955988209 0.833062958 0.293087138 0.079394914 0.253621653 3.451297727 0.012284446 0.024278503 1.31E-06 5.882735611 -0.122925251 AGTFIAPPVYSNITPYQS(ph)HLRSPVR ddPTM_HeLa_Curcumin_4h_R1 2 AGTFIAPPVYSNITPYQSHLRSPVR 25 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 0 AGTFIAPPVY(0.003)S(0.004)NIT(0.015)PY(0.067)QS(0.659)HLRS(0.252)PVR;AGTFIAPPVYSNIT(0.001)PY(0.197)QS(0.632)HLRS(0.17)PVR ; 76.267 0.00014237 64122000 2364.06 1960.04 2240 2127.2 2250.9 5258.8 3386.3 1879.93 2704 2216.81 TRUE FALSE FALSE 2176.942156 2129.457124 2323.016371 2118.39821 2224.059488 4168.065601 3481.310464 2453.112003 2407.377965 2293.843982 0.949036714 0.928335641 1.012717686 0.923514514 0.969577489 1.817065865 1.517675348 1.069432804 1.049495076 1 11.16355155 -5.291700575 23.95894154 0.970185804 1.473019699 0.631332871 0.172223523 168.1163445 133103.8795 0.022861428 0.051127521 5.11E-06 5.291700575 0.502833895 AGTGVDNVDLEAATR ddPTM_HeLa_Curcumin_4h_R1 2 AGTGVDNVDLEAATR 15 0 A0A286YF22;A0A2C9F2M7;O43175;A0A286YFL2;A0A286YFA2;A0A286YFM8;A0A286YER3;A0A286YFC8;A0A286YFB2 A0A286YF22 PHGDH D-3-phosphoglycerate dehydrogenase 0 0 ; ; 195.71 3.60E-12 8139200 3187.6 2438.4 2613.5 2686.9 2492.2 3380.3 2618.2 2582.5 3005.2 2379.49 FALSE FALSE TRUE 2935.298096 2649.164431 2710.358609 2675.78232 2462.482143 2679.187676 2691.659645 3369.892362 2675.537079 2462.1771 1.19215555 1.0759439 1.100797586 1.086754612 1.000123891 1.088137679 1.093203103 1.368663676 1.086655009 1 11.26571882 -9.55831396 1.329007672 0.999969437 1.125198006 0.08001016 0.096353156 0.582233575 1.841996279 0.065285274 0.01537858 2.76E-10 9.55831396 0.125228569 AGTGYAS(ph)PDRTHVLAAGK ddPTM_HeLa_Curcumin_4h_R1 1 AGTGYASPDRTHVLAAGK 18 1 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 0 AGT(0.252)GY(0.014)AS(0.732)PDRT(0.002)HVLAAGK 74.703 0.0044636 26983000 3138.4 2536.3 2831.7 3181 2798.2 3247.6 2420.8 1344.5 3392.3 3172.2 TRUE FALSE FALSE 2889.992328 2755.52647 2936.645293 3167.837865 2764.833293 2574.011152 2488.721133 1754.431861 3020.173177 3282.433714 0.880441947 0.839476654 0.894654866 0.965088145 0.842311996 0.784177649 0.758193874 0.534491177 0.920101803 1 11.68055016 -3.616445544 0.529942002 0.939755414 5.22E-32 0.841380506 0.049648203 2.280508215 0.265871201 0.011739219 1.545663951 0.000241855 3.616445544 -0.939755414 AGTLSITEFADMLSGNAGGFRS(ph)R ddPTM_HeLa_Curcumin_4h_R1 5 AGTLSITEFADMLSGNAGGFRSR 23 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 AGTLSITEFADMLS(0.023)GNAGGFRS(0.977)R;AGTLSITEFADMLS(0.004)GNAGGFRS(0.996)R;AGTLSITEFADMLSGNAGGFRS(1)R;AGTLSITEFADMLS(0.021)GNAGGFRS(0.979)R;AGTLSITEFADMLSGNAGGFRS(1)R ;;;; 204.73 3.44E-18 471624400 5442.95 3653.39 4226.09 4775.51 3793.45 6557.66 5261.63 2731.83 5737.79 4740.65 TRUE FALSE FALSE 5012.134764 3969.172752 4382.712613 4755.750205 3748.215586 5197.527396 5409.257177 3564.752391 5108.368792 4905.387235 1.021761285 0.809145652 0.893448856 0.969495369 0.764101876 1.059554964 1.102717669 0.726701526 1.041379314 1 12.26015131 -7.334200918 24.99910093 1.01027624 0.914030271 0.176416982 0.114042386 206.2290447 70854.44561 0.018568447 0.021233819 4.63E-08 7.334200918 -0.096245969 SLLLPPPPFHGS(ph)ISR ddPTM_HeLa_Curcumin_4h_R1 1 SLLLPPPPFHGSISR 15 0 A0A2R8YGQ0;A0A2R8Y7I3;A0A2R8YFQ2;A0A2R8Y466;A0A2R8YFJ9;A0A2R8Y5U9;A0A2R8Y7S4;Q6P4D5-2;Q6P4D5 A0A2R8YGQ0 FAM122C Protein FAM122C 1 0 SLLLPPPPFHGS(0.979)IS(0.021)R 80.387 0.015512 27212000 4503.8 5743.7 3610 7230.5 4068.8 360.73 1393.9 1315.6 5622.9 4544.6 TRUE FALSE FALSE 4147.319478 6240.159835 3743.789776 7200.582107 4020.282217 285.9105317 1433.009083 1716.720384 5006.081938 4702.524512 0.881934686 1.32698082 0.796123394 1.531216284 0.854919992 0.060799371 0.304731869 0.365063569 1.064552014 1 12.19921975 -5.365222429 5.277146205 1.005485745 0.253246351 0.737481054 0.223894254 0.088698939 3.671347808 0.030960497 0.070580216 4.31E-06 5.365222429 -0.752239394 down AGTPIRDSHS(ph)PDLQLPTPEVIPSSGSK ddPTM_HeLa_Curcumin_4h_R1 1 AGTPIRDSHSPDLQLPTPEVIPSSGSK 27 1 H3BPE1;H3BQK9;H0Y6T5;H0Y4F5 H3BPE1 MACF1 1 0 AGT(0.043)PIRDS(0.477)HS(0.48)PDLQLPT(0.001)PEVIPSSGSK 75.794 7.86E-05 19529000 1872.5 1588.8 1458.1 1775 958.57 860.65 483.33 312.35 1861.6 1990.4 TRUE FALSE FALSE 1724.289649 1726.128792 1512.138469 1767.65552 947.1396788 682.1414885 496.890939 407.5840771 1657.387137 2059.566252 0.837210091 0.838103067 0.734202392 0.858265918 0.459873373 0.331206383 0.241259993 0.197898017 0.804726304 1 11.00812482 -5.364398018 0.581190529 0.937605999 0.032347182 0.906619377 0.08494348 0.257833759 0.118546885 0.016994323 0.124887192 4.32E-06 5.364398018 -0.905258817 down AGTQIENIDEDFRDGLK ddPTM_HeLa_Curcumin_4h_R1 2 AGTQIENIDEDFRDGLK 17 1 O43707;F5GXS2;O43707-3;K7EP19 O43707 ACTN4 Alpha-actinin-4 0 0 ; ; 205.95 8.36E-11 34703000 6796.5 6025.1 7112.9 6423.6 8019.2 8768.1 7329.1 7347.5 6638.8 6709 FALSE FALSE TRUE 6258.549853 6545.882797 7376.510331 6397.020845 7923.576278 6949.497223 7534.734821 9587.718926 5910.540249 6942.137251 0.9015307 0.942920395 1.062570512 0.92147715 1.141374189 1.001060188 1.085362411 1.381090373 0.851400662 1 12.76116417 -1.000000001 0.658372308 0.96082868 38.84384466 0.734271028 0.074573575 75.55195729 0.438457594 0.011519524 4187.563822 0.1 1.000000001 37.88301598 AGTQIENIEEDFR ddPTM_HeLa_Curcumin_4h_R1 1 AGTQIENIEEDFR 13 0 P12814-4;P12814-3;P12814;P12814-2;G3V2N5;A0A494C1A0;P35609-2;P35609;G3V5M4;G3V380;A0A087WSZ2;Q08043;A0A494C166;A0A494C033;A0A494C0Q3 P12814-4 ACTN1;ACTN2;ACTN3 Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 0 0 126.32 0.016391 2460400 612.53 557.55 769.09 594.58 624.31 776.65 641.46 448.01 635.73 619.56 FALSE FALSE TRUE 564.0476042 605.7421376 797.593152 592.1197855 616.865511 615.5640354 659.4576412 584.6061866 565.9920095 641.0896639 0.879826389 0.944863366 1.24412106 0.923614619 0.962214095 0.960183996 1.028651183 0.911894575 0.882859359 1 9.324382338 -6.949044578 24.99998451 0.941622917 1.006486757 0.136291943 0.093573854 196.0562029 96189.32692 0.015358781 0.020185391 1.12E-07 6.949044578 0.06486384 AGTQIENIEEDFRDGLK ddPTM_HeLa_Curcumin_4h_R1 2 AGTQIENIEEDFRDGLK 17 1 P12814-4;P12814-3;P12814;P12814-2;G3V2N5;G3V5M4;G3V380 P12814-4 ACTN1 Alpha-actinin-1 0 0 ; ; 179.66 7.44E-06 19040500 3387.58 2589.2 3143.68 2962.51 3127.05 3704.64 2883.9 2841.88 3201.72 2522.64 FALSE FALSE TRUE 3119.449468 2812.998911 3260.187546 2950.251919 3089.761971 2936.255904 2964.814472 3708.35613 2850.499326 2610.301552 1.195053294 1.077652851 1.2489697 1.130234136 1.183680088 1.124872297 1.135813014 1.420661964 1.092019167 1 11.35000077 -13.52287875 0.184139958 0.193225162 1.229304291 0.308208943 0.090100549 38.89220472 0.452140736 11.28492808 0.106167639 3.00E-14 13.52287875 1.036079129 AGVAPLQVK ddPTM_HeLa_Curcumin_4h_R1 1 AGVAPLQVK 9 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 104.45 0.0009104 0 4914.5 2892.6 4359.3 3485.1 4074 4324.4 3710.3 3554.7 3653.5 4714.3 FALSE FALSE TRUE 4525.512139 3142.623455 4520.859493 3470.67958 4025.420211 3427.470694 3814.401032 4638.511666 3252.720191 4878.121574 0.927716145 0.644228195 0.926762366 0.711478697 0.825198829 0.702621007 0.781940543 0.950880702 0.666797689 1 12.25211 -7.462730175 8.06919055 0.968362269 0.790795469 0 0.131485968 0.198625668 24.39589196 0.014529019 0.016468015 3.45E-08 7.462730175 -0.1775668 AGVDYAPNLPPFPS(ph)PADVK ddPTM_HeLa_Curcumin_4h_R1 1 AGVDYAPNLPPFPSPADVK 19 0 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 0 AGVDYAPNLPPFPS(1)PADVK 97.083 0.0019015 0 942.6 986.81 1078 1107.4 1182.7 1580.4 1795.9 1103.8 820.52 734.16 TRUE FALSE FALSE 867.9922154 1072.105459 1117.951628 1102.817872 1168.597075 1252.607225 1846.288121 1440.343539 730.5110088 759.6720054 1.142588129 1.411274144 1.471624096 1.451702662 1.538291614 1.648879011 2.430375356 1.89600713 0.961613701 1 9.569232847 -4.757645835 0.320268928 0.987322392 2.837744839 0.799746915 0.185828925 1.487220217 0.139286358 0.075702808 1.025778425 1.75E-05 4.757645835 1.850422447 AGVLAGHDNR ddPTM_HeLa_Curcumin_4h_R1 2 AGVLAGHDNR 10 0 P62879;E7EP32;P62879-2;Q9HAV0;B3KVK2;P62873-2;P62873 P62879 GNB2;GNB4;GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;Guanine nucleotide-binding protein subunit beta-4;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0 0 ; ; 128.03 0.0025526 4782500 7129.6 3794.5 5351.5 4669.6 6659.6 8694.7 6616.9 7059.2 6173.1 5360.6 FALSE FALSE TRUE 6565.284637 4122.479672 5549.831298 4650.278432 6580.18862 6891.321211 6802.552406 9211.517583 5495.926374 5546.880451 1.183599447 0.743206872 1.000531983 0.838359232 1.18628636 1.242377814 1.22637444 1.660666327 0.990813922 1 12.43746092 -3.562588328 0.864925524 1.043282476 3.092156338 0.676519862 0.138392269 3.334502018 0.781184451 0.023638293 8.677754783 0.000273786 3.562588328 2.048873862 AGVLAHLEEER ddPTM_HeLa_Curcumin_4h_R1 4 AGVLAHLEEER 11 0 P35579;P35579-2;P35580;P35580-5;P35580-2;P35580-3;P35580-4 P35579;P35580 MYH9;MYH10 Myosin-9;Myosin-10 0 0 ;;; ;;; 178.46 8.97E-05 85004500 20440.7 19929.6 19342 19742.7 19995 18749.7 17823.8 16317.1 18705.7 18501.9 FALSE FALSE TRUE 18822.79703 21652.22582 20058.83153 19661.00994 19756.57268 14860.80087 18323.88786 21292.10868 16653.73151 19144.83965 0.98317862 1.130969296 1.047740901 1.026961327 1.031952894 0.776230104 0.9571189 1.112159154 0.869880961 1 14.22466796 AGVLAHLEEERDLK ddPTM_HeLa_Curcumin_4h_R1 2 AGVLAHLEEERDLK 14 1 P35579;P35579-2;P35580;P35580-5;P35580-2;P35580-3;P35580-4 P35579;P35580 MYH9;MYH10 Myosin-9;Myosin-10 0 0 ; ; 141.89 0.0003324 44986000 18154.1 15255.1 12792.5 16769.8 10467.1 14640.4 13061.6 11540.6 22661.9 19050.7 FALSE FALSE TRUE 16717.18383 16573.68287 13266.6013 16700.41101 10342.28667 11603.81601 13428.07334 15059.27581 20175.94627 19712.71041 0.848040857 0.840761241 0.672997322 0.847189994 0.524650667 0.5886464 0.681188587 0.763937353 1.023499349 1 14.26683853 -7.309074047 0.500966231 0.983730404 0.642374219 0.690872304 0.086815063 0.342149236 0.206769169 0.034800103 0.039434482 4.91E-08 7.309074047 -0.341356184 AGVLT(ph)PPDLGPHPPPPAPR ddPTM_HeLa_Curcumin_4h_R1 2 AGVLTPPDLGPHPPPPAPR 19 0 I3L2J0 I3L2J0 CIC 1 0 AGVLT(1)PPDLGPHPPPPAPR;AGVLT(1)PPDLGPHPPPPAPR ; 105.68 0.00062199 12095500 6137.9 4905.5 4989.3 5497.8 4964.4 6251.5 4465 3185 7470.8 5519.7 TRUE FALSE FALSE 5652.078738 5329.509562 5174.207847 5475.05156 4905.202772 4954.868431 4590.275883 4156.091838 6651.271931 5711.509164 0.98959462 0.933117572 0.90592656 0.958599803 0.858827786 0.867523502 0.803688789 0.727669644 1.164538433 1 12.47965629 -2.463019689 0.283415289 1.007707672 2.89E-19 0.756855761 0.056201897 3.510895584 0.093110726 0.010000895 1.505644181 0.003443343 2.463019689 -1.007707672 ASPRPWT(ph)PEDPWSLYGPSPGGR ddPTM_HeLa_Curcumin_4h_R1 1 ASPRPWTPEDPWSLYGPSPGGR 22 1 Q14934-2;Q14934-9;Q14934-3;Q14934-4;Q14934-5;Q14934-6;Q14934-7;Q14934;Q14934-8;Q14934-10;Q14934-18;Q14934-11;Q14934-12;Q14934-13;Q14934-14;Q14934-15;Q14934-16;Q14934-17 Q14934-2 NFATC4 "Nuclear factor of activated T-cells, cytoplasmic 4" 1 0 AS(0.15)PRPWT(0.849)PEDPWSLY(0.001)GPSPGGR 54.828 0.012672 17306000 1251.3 1005.8 1269.2 993.31 935.26 576.68 575.44 197.92 1097.7 1004 TRUE FALSE FALSE 1152.258285 1092.73687 1316.237669 989.1999464 924.1076353 457.0700675 591.5852977 258.2648969 977.2850563 1038.888925 1.109125583 1.051832245 1.266966695 0.952171038 0.88951534 0.439960477 0.569440374 0.248597218 0.94070216 1 10.0208257 -5.351258982 1.714923831 1.067528151 0.390800057 0.866814422 0.111467066 0.086557104 0.486013119 0.015265948 0.048205909 4.45E-06 5.351258982 -0.676728094 down AGVNSDSPNNCSGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 AGVNSDSPNNCSGKK 15 1 F8WE62;Q9Y4C1 F8WE62 KDM3A Lysine-specific demethylase 3A 0 1 AGVNSDSPNNCSGK(1)K 153.81 0.0009588 709980 343.25 314.53 337.07 354.4 307.8 333.51 227.61 150.32 238.31 266.04 FALSE TRUE FALSE 316.0814003 341.7165717 349.5621107 352.9335867 304.129686 264.3362666 233.996124 196.151876 212.1679892 275.2848702 1.148197502 1.241319842 1.269819553 1.282066778 1.104781697 0.960228095 0.850014474 0.712541433 0.770721577 1 8.104781511 -4.817608118 1.767741555 1.117996132 0.729213728 0.476738025 0.143088197 0.228863305 1.281583287 0.017527834 0.103836341 1.52E-05 4.817608118 -0.388782403 AGVNTVTTLVENK ddPTM_HeLa_Curcumin_4h_R1 2 AGVNTVTTLVENK 13 0 P62424;Q5T8U2;Q5T8U3 P62424 RPL7A 60S ribosomal protein L7a 0 0 ; ; 208.74 1.00E-70 3543400 847.64 532.56 628.61 736.25 616.01 310.5 479.76 628.09 1073.04 751.16 FALSE FALSE TRUE 780.5483996 578.5921134 651.9068396 733.2035926 608.6644831 246.0987999 493.2207744 819.5917496 955.3301966 777.2627541 1.0042272 0.744397066 0.838721315 0.943314971 0.783087161 0.316622402 0.634561185 1.054459056 1.229095556 1 9.602258575 -6.63022345 0.747927765 1.007314585 0.684647422 0.323906968 0.199204529 0.560258096 0.630978672 0.041473599 0.075850758 2.34E-07 6.63022345 -0.322667164 AGVNTVTTLVENK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 AGVNTVTTLVENKK 14 1 P62424;Q5T8U2;Q5T8U3 P62424 RPL7A 60S ribosomal protein L7a 0 1 AGVNTVTTLVENK(1)K 195.72 3.87E-13 1354400 405.46 512.25 703.12 379.1 425.93 713.17 741.35 879.84 840.99 419.62 FALSE TRUE FALSE 373.3674132 556.5266075 729.1782457 377.5313846 420.8510629 565.2505029 762.1502858 1148.099166 748.7355011 434.2017638 0.85989382 1.281723507 1.679353486 0.869483766 0.969252311 1.301815308 1.755290626 2.64416053 1.724395347 1 8.762221776 -4.183291195 1.142185712 1.008277332 3.65553938 0.610004992 0.330395705 0.614797603 0.576451581 0.039229793 2.023510147 6.56E-05 4.183291195 2.647262048 AGVNTVTTLVENKK ddPTM_HeLa_Curcumin_4h_R1 2 AGVNTVTTLVENKK 14 1 P62424;Q5T8U2;Q5T8U3 P62424 RPL7A 60S ribosomal protein L7a 0 0 ; ; 107.5 0.00064643 6879600 2888.3 2310.6 2660.2 2910 2639.9 2802.5 2832.5 2508.2 3075.2 2910.4 FALSE FALSE TRUE 2659.688007 2510.317968 2758.789352 2897.959191 2608.420917 2221.229909 2911.972327 3272.938634 2737.858254 3011.536183 0.883166545 0.833567261 0.916073786 0.962286028 0.866142977 0.737573708 0.96693918 1.086800368 0.90912348 1 11.55628388 -9.260993416 1.009491161 0.999564805 0.900885318 0.001209906 0.091163127 0.83578759 1.537750326 0.058176235 0.01616653 5.48E-10 9.260993416 -0.098679487 AGVQADEDEDGDEKDEK ddPTM_HeLa_Curcumin_4h_R1 1 AGVQADEDEDGDEKDEK 17 1 P26358;P26358-2 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 0 0 107.13 0.00088657 0 2136.1 2049.6 2089.4 2111.9 2116.4 1956.5 1981.3 1511.4 2657.1 2351.4 FALSE FALSE TRUE 1967.025431 2226.758291 2166.835002 2103.161517 2091.163312 1550.699846 2036.889946 1972.218902 2365.622778 2433.110975 0.808440491 0.915189777 0.890561517 0.864391941 0.859460721 0.637332149 0.837154559 0.810574989 0.97226259 1 11.24858641 -13.52287875 0.180494314 1.747661881 0.77984207 0.494963487 0.067943013 36.32702171 0.417584399 9.59539206 0.097625341 3.00E-14 13.52287875 -0.96781981 AGVVNGTGAPGQS(ph)PGAGR ddPTM_HeLa_Curcumin_4h_R1 2 AGVVNGTGAPGQSPGAGR 18 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;Q13330-2 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 0 AGVVNGTGAPGQS(1)PGAGR;AGVVNGTGAPGQS(1)PGAGR ; 239.87 7.82E-32 23697700 2207.5 1847.87 2072.2 2134 2107.64 3658.6 2383.78 1429.87 2499.9 1834.62 TRUE FALSE FALSE 2032.774046 2007.591649 2148.997555 2125.170073 2082.50777 2899.765119 2450.662451 1865.830781 2225.667224 1898.372908 1.07079807 1.057532817 1.132020766 1.119469238 1.096996149 1.527500264 1.290927847 0.982857884 1.17240781 1 10.8905477 -5.965531098 1.297325446 1.038377076 1.25851176 0.166406799 0.13905066 0.374864685 1.254193577 0.021357654 0.048999138 1.08E-06 5.965531098 0.220134684 AGYLSDGDS(ph)PERPAGPPS(ph)PTSFRPYEVGPAAR ddPTM_HeLa_Curcumin_4h_R1 1 AGYLSDGDSPERPAGPPSPTSFRPYEVGPAAR 32 2 Q6ZW31;Q6ZW31-2 Q6ZW31 SYDE1 Rho GTPase-activating protein SYDE1 2 0 AGY(0.001)LS(0.006)DGDS(0.895)PERPAGPPS(0.503)PT(0.388)S(0.154)FRPY(0.052)EVGPAAR 45.666 0.015794 14187000 1268.6 1432.5 1141.6 1560.4 1391 1547.6 1356.8 911.71 1607.3 1187.5 TRUE FALSE FALSE 1168.188971 1556.318917 1183.9087 1553.943478 1374.413233 1226.610315 1394.868156 1189.686182 1430.983211 1228.765537 0.950701282 1.2665711 0.963494389 1.264637908 1.118531724 0.998246027 1.135178449 0.968196248 1.164569781 1 10.26299394 AGYTDKVVIGMDVAASEFFR ddPTM_HeLa_Curcumin_4h_R1 1 AGYTDKVVIGMDVAASEFFR 20 1 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 0 86.016 0.0015578 6161900 1160.5 1115.4 920.68 1367.6 986.64 1822.4 1419.6 1500.2 1630.9 1488 FALSE FALSE TRUE 1068.6452 1211.810206 954.8012107 1361.941234 974.8749624 1444.413697 1459.430155 1957.604074 1451.99435 1539.707889 0.694057105 0.787039031 0.620118412 0.884545207 0.633155788 0.938108915 0.947861712 1.271412641 0.943032351 1 10.58844096 -4.180282355 1.5235264 0.819793871 1.505362546 0.562739512 0.123818576 0.934653659 1.706294861 0.021169087 1.013248587 6.60E-05 4.180282355 0.685568675 AHADDELAALR ddPTM_HeLa_Curcumin_4h_R1 2 AHADDELAALR 11 0 P48681 P48681 NES Nestin 0 0 ; ; 172.21 2.59E-14 0 3778.4 3437.9 3531.2 4109.2 3641.2 4352.4 3367.5 2667.3 4067.4 3261.6 FALSE FALSE TRUE 3479.335653 3735.056757 3662.069378 4092.197219 3597.781068 3449.663178 3461.982987 3480.547491 3621.216396 3374.940357 1.030932486 1.106703041 1.085076769 1.212524307 1.066028044 1.022140486 1.025790865 1.031291556 1.072971968 1 11.72064629 -7.473655513 3.486604451 1.012628632 1.079164175 0.08170472 0.05576581 0.267917708 6.308029017 0.010143024 0.011219199 3.36E-08 7.473655513 0.066535543 AHAS(ph)PFSGALTPSAPPGPEMNR ddPTM_HeLa_Curcumin_4h_R1 1 AHASPFSGALTPSAPPGPEMNR 22 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;O15027-4 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 AHAS(0.979)PFS(0.021)GALTPSAPPGPEMNR 159.5 8.84E-07 4948200 1779.2 1356.1 1042.8 1300.3 1628.3 2215.9 1348.3 735.88 1493.5 1316 TRUE FALSE FALSE 1638.374443 1473.315241 1081.447085 1294.919703 1608.883586 1756.297362 1386.129669 960.2464244 1329.666787 1361.730902 1.203155807 1.081943018 0.794170922 0.950936563 1.181498917 1.289753621 1.017917466 0.705166067 0.976453413 1 10.41122592 -6.973334927 24.99977366 1.098388176 1.005606323 0.027637017 0.168911838 548.8186632 514542.1821 0.02904974 0.038178407 1.06E-07 6.973334927 -0.092781853 AHFNAMFQPS(ph)SPTR ddPTM_HeLa_Curcumin_4h_R1 1 AHFNAMFQPSSPTR 14 0 Q8WUA4;H0Y4Q6 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 0 AHFNAMFQPS(0.493)S(0.493)PT(0.014)R 95.195 0.0074084 24737000 1503.1 1304.1 1421.4 1248.9 1757.4 2222.7 1404.4 764.47 1837.2 1300.1 TRUE FALSE FALSE 1384.128049 1416.820593 1474.078334 1243.732383 1736.444153 1761.686965 1443.803684 997.5533838 1635.663756 1345.278378 1.028878536 1.053180231 1.095742233 0.924516742 1.290769391 1.309533397 1.073237857 0.741521904 1.215855233 1 10.39368902 -7.025351256 1.002567793 1.009928124 1.092462688 0 0.167374227 1.322019222 2.614682433 0.032483766 0.04365105 9.43E-08 7.025351256 0.082534564 AHFNAMFQPSS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 AHFNAMFQPSSPTR 14 0 Q8WUA4;H0Y4Q6 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 0 AHFNAMFQPS(0.104)S(0.793)PT(0.104)R 132.51 0.0010099 23980000 1764.2 1104.9 1199.8 1321.9 1557.1 1840.2 1359.9 967.09 1793.8 1463.3 TRUE FALSE FALSE 1624.561708 1200.402633 1244.265643 1316.430328 1538.532599 1458.521777 1398.055134 1261.951289 1597.024628 1514.149566 1.072920235 0.792789999 0.821758743 0.869418951 1.016103451 0.963261364 0.923326972 0.833438993 1.054733735 1 10.564292 -7.278317811 24.98731748 1.034434558 0.894390954 0.532006192 0.065886453 539.5504988 798764.5156 0.012470321 0.014279146 5.27E-08 7.278317811 -0.140043603 AHGELHEQFK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 AHGELHEQFKR 11 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 0 1 ; AHGELHEQFK(1)R;AHGELHEQFK(1)R 95.483 0.0012956 10491700 2798.6 1960 2848.1 2882.9 2650.6 3195.1 2419.1 2033.41 2752.3 2594.3 FALSE TRUE FALSE 2577.087857 2129.413666 2953.653091 2870.971324 2618.993326 2532.400244 2486.973435 2653.387348 2450.379576 2684.451732 0.960005288 0.793239693 1.100281691 1.069481447 0.975615726 0.943358457 0.926436265 0.988428034 0.912804483 1 11.39041175 -4.68902768 0.003021085 1.932938953 4.42E-05 0 0.082079017 335924.732 185.4398422 58225.9273 60433.49888 2.05E-05 4.68902768 -1.932894743 AHGS(ph)VFY(ph)QIMT(ph)MRRQPQLLVK ddPTM_HeLa_Curcumin_4h_R1 1 AHGSVFYQIMTMRRQPQLLVK 21 2 C9JNM7;O15259-3;O15259-2;O15259;O15259-4 C9JNM7 NPHP1 Nephrocystin-1 3 0 AHGS(1)VFY(1)QIMT(1)MRRQPQLLVK 48.489 0.01284 6901000 915.66 675.03 667.26 609.66 976.28 1429.9 883.7 793.76 854.07 888.76 TRUE FALSE FALSE 843.1845448 733.3765853 691.9892426 607.1373885 964.6384986 1133.322622 908.4942436 1035.77377 760.3806578 919.6443438 0.916859382 0.797456745 0.752453106 0.660187161 1.048925604 1.23234882 0.987875639 1.126276453 0.826820349 1 9.844932222 -5.53769265 24.9998325 0.907855643 1.109054454 0.497896262 0.119581903 206.0503531 347728.2866 0.019602258 0.039215546 2.90E-06 5.53769265 0.201198811 AHLDHIPDYTPPLLTTIS(ph)PEQESDER ddPTM_HeLa_Curcumin_4h_R1 2 AHLDHIPDYTPPLLTTISPEQESDER 26 0 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;K7EM61 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 0 AHLDHIPDYTPPLLT(0.046)T(0.166)IS(0.605)PEQES(0.183)DER;AHLDHIPDYTPPLLT(0.003)T(0.007)IS(0.894)PEQES(0.096)DER ; 87.155 2.07E-05 7712300 1891.86 1534.01 1722.21 1615.32 1744.4 1787.7 1670.25 1441.63 1933 1527.21 TRUE FALSE FALSE 1742.117285 1666.602989 1786.036618 1608.636234 1723.599169 1416.910868 1717.11272 1881.176351 1720.954736 1580.280434 1.10241021 1.054624833 1.130202323 1.017943524 1.090691964 0.89661989 1.086587344 1.190406658 1.089018569 1 10.62596488 -9.50633158 1.258757935 1.000042871 1.070249481 0 0.07759545 0.82869309 2.352347757 0.049718809 0.012052375 3.12E-10 9.50633158 0.07020661 AHLS(ph)ENELEALEK ddPTM_HeLa_Curcumin_4h_R1 2 AHLSENELEALEK 13 0 P98175-5;P98175-2;P98175;P98175-4;P98175-3 P98175-5 RBM10 RNA-binding protein 10 1 0 AHLS(1)ENELEALEK;AHLS(1)ENELEALEK ; 156.72 3.89E-06 3901000 9312 7668.9 9244.7 8203.4 9259.7 10489.1 7285.4 6314.53 8093.7 7135.3 TRUE FALSE FALSE 8574.945374 8331.765544 9587.316714 8169.456504 9149.284125 8313.542423 7489.808716 8239.801128 7205.841359 7383.251144 1.161405078 1.128468392 1.298522362 1.106484981 1.239194489 1.126000222 1.014432338 1.116012576 0.975971319 1 12.85004052 -9.160164306 0.870821806 0.998346126 1.149588089 0.427642919 0.073456658 0.53695899 0.722397661 0.052269989 0.014361496 6.92E-10 9.160164306 0.151241963 AEEPLK(ac)TVQEK ddPTM_HeLa_Curcumin_4h_R1 1 AEEPLKTVQEK 11 1 Q05GC8;Q96PN7-2;Q96PN7-3;Q96PN7-4;Q96PN7-5;Q96PN7 Q05GC8 BCAR2;TRERF1 Transcriptional-regulating factor 1 0 1 AEEPLK(1)TVQEK 231.07 2.59E-40 2775100 926.21 981.33 918.02 861.16 890.14 770.56 397.44 194.11 963.45 717.2 FALSE TRUE FALSE 852.8995012 1066.151792 952.0426288 857.5967481 879.5256619 610.73717 408.5910967 253.2932454 857.7619454 742.1226466 1.149270279 1.436624792 1.282864272 1.155599754 1.185148662 0.822959888 0.550570851 0.341309144 1.155822355 1 9.535513823 -4.841885568 1.883268008 1.13018249 0.363383476 0.855758454 0.122612517 0.130293095 0.853713227 0.021881196 0.117333074 1.44E-05 4.841885568 -0.766799014 down AHPPELK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AHPPELKK 8 1 C9JVQ0;P62308;A8MWD9 C9JVQ0 SNRPG;SNRPGP15 Small nuclear ribonucleoprotein G;Putative small nuclear ribonucleoprotein G-like protein 15 0 1 ; AHPPELK(1)K;AHPPELK(1)K 88.37 0.005833 4621700 5146.4 6340.1 4580.9 4461.1 7355.1 11604.3 8229.5 6967 9589.1 4943.4 FALSE TRUE FALSE 4739.05701 6888.109993 4750.672184 4442.64115 7267.395236 9197.437373 8460.397621 9091.206228 8537.199721 5115.182782 0.926468752 1.34660095 0.928739477 0.868520508 1.420749863 1.798066221 1.653977577 1.77729841 1.668992113 1 12.32057008 -5.559155079 3.54752135 0.987723502 1.726703338 0.509654686 0.251744394 0.057464733 1.516562282 0.019234629 0.041876882 2.76E-06 5.559155079 0.738979836 AHQLVMEGYNWCHDR ddPTM_HeLa_Curcumin_4h_R1 2 AHQLVMEGYNWCHDR 15 0 P67775;P62714;H0YC23 P67775 PPP2CA;PPP2CB Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform;Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform 0 0 ; ; 80.719 0.0044408 34437000 2264.1 2203 2318.7 2145.2 2810.8 4091.1 2742.4 2677.9 2635.8 2629.3 FALSE FALSE TRUE 2084.894096 2393.417504 2404.633062 2136.323731 2777.283046 3242.559744 2819.344363 3494.379382 2346.659334 2720.667979 0.76631699 0.879716864 0.883839219 0.785220301 1.020809252 1.191824864 1.036269175 1.284382883 0.862530582 1 11.40974519 -5.515226448 4.27540754 0.879354827 1.153587126 0.731348585 0.083360103 0.108240365 4.753074246 0.015029232 0.03291445 3.05E-06 5.515226448 0.274232299 AHS(ph)LLFENSDSFSEDSSTLGR ddPTM_HeLa_Curcumin_4h_R1 2 AHSLLFENSDSFSEDSSTLGR 21 0 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 0 AHS(1)LLFENSDSFSEDSSTLGR;AHS(1)LLFENSDSFSEDSSTLGR ; 182.47 2.56E-10 19913300 3316 2466.8 2750.5 2810.75 3118.92 4821.2 3511.3 4081.2 3322.5 2981.3 TRUE FALSE FALSE 3053.535101 2680.0192 2852.43595 2799.119861 3081.728916 3821.228774 3609.817628 5325.539092 2958.030062 3084.899953 0.989832781 0.868754009 0.924644557 0.907361634 0.998972078 1.238688072 1.170157115 1.726324734 0.958873904 1 11.59100799 -2.346587655 0.786129072 0.973799481 16.55979216 0.908175661 0.07331399 9.077395869 0.321731665 0.012055427 226.9968264 0.004502071 2.346587655 15.58599268 AHS(ph)PAEGASVESS(ph)SPGPK ddPTM_HeLa_Curcumin_4h_R1 1 AHSPAEGASVESSSPGPK 18 0 Q8NFG4;C9J4C4;Q8NFG4-3;Q8NFG4-2 Q8NFG4 FLCN Folliculin 2 0 AHS(1)PAEGASVES(0.032)S(0.625)S(0.343)PGPK 140.47 0.00063915 17520000 6490 4845.7 5315.7 5357.1 5741.2 6066.7 3866.6 2077.8 5807.7 5042.1 TRUE FALSE FALSE 5976.309652 5264.540716 5512.704518 5334.93374 5672.73994 4808.398034 3975.08639 2711.311655 5170.60984 5217.3126 1.14547663 1.009052192 1.056617638 1.022544392 1.087291557 0.921623526 0.761903051 0.519675907 0.991048503 1 12.34909116 -4.456534016 1.213832729 1.064159905 0.377265029 0.921230548 0.048830105 0.22982741 0.356787978 0.008684404 0.180276389 3.50E-05 4.456534016 -0.686894876 AHS(ph)PAEGASVESSS(ph)PGPK ddPTM_HeLa_Curcumin_4h_R1 1 AHSPAEGASVESSSPGPK 18 0 Q8NFG4;C9J4C4;Q8NFG4-3;Q8NFG4-2 Q8NFG4 FLCN Folliculin 2 0 AHS(1)PAEGASVES(0.001)S(0.309)S(0.691)PGPK 142.93 0.00053163 16816000 7513.1 6127.6 6587.8 6368.2 6947.9 7284.5 4625 2699.8 8016.6 6572.2 TRUE FALSE FALSE 6918.430207 6657.24244 6831.949663 6341.850076 6865.05083 5773.612587 4754.765052 3522.956592 7137.199037 6800.583461 1.017328917 0.978922247 1.004612281 0.932544996 1.009479682 0.848987829 0.699170164 0.518037403 1.049498043 1 12.73144281 -4.51273562 1.06412772 1.004098477 0.383669458 0.966177085 0.029928237 0.119224088 0.140392994 0.003772901 0.075010264 3.07E-05 4.51273562 -0.620429019 AHS(ph)PAEGASVESSSPGPK ddPTM_HeLa_Curcumin_4h_R1 1 AHSPAEGASVESSSPGPK 18 0 Q8NFG4;C9J4C4;Q8NFG4-3;Q8NFG4-2 Q8NFG4 FLCN Folliculin 1 0 AHS(1)PAEGASVESSSPGPK 89.659 0.0014083 7343700 3742.7 3049.6 3075.9 3013 3730.3 3623.7 2673.8 2105.8 3895.2 3419.9 TRUE FALSE FALSE 3446.461346 3313.193835 3189.89556 3000.533004 3685.818609 2872.103772 2748.819632 2747.848726 3467.906305 3538.74127 0.973922952 0.936263372 0.901420962 0.847909687 1.041562049 0.811617339 0.776778923 0.776504558 0.979983005 1 11.78902057 -2.10618272 0.258784248 1.003074255 4.47E-12 0.607403922 0.057415236 12.15012794 0.253435379 0.029484895 4.829027177 0.007831001 2.10618272 -1.003074255 AHS(ph)VDVEK ddPTM_HeLa_Curcumin_4h_R1 1 AHSVDVEK 8 0 Q6IQ19;Q6IQ19-2 Q6IQ19 CCSAP "Centriole, cilia and spindle-associated protein" 1 0 AHS(1)VDVEK 85.29 0.012418 5056000 4164.5 4390.8 3936.6 3606.9 4340 5362.2 4017.4 3864.7 4540.9 3845.6 TRUE FALSE FALSE 3834.875431 4770.321187 4082.493859 3591.975604 4288.248335 4250.019276 4130.117432 5043.029239 4042.774631 3979.234314 0.963721945 1.198803793 1.025949602 0.902680094 1.077656654 1.068049514 1.037917626 1.267336588 1.015967976 1 11.95827514 -1.000000026 0.847664923 1.001545167 89.78073694 0.424001599 0.077271211 418.015919 1.107114695 0.012253079 71589.90093 0.099999994 1.000000026 88.77919177 AHSENEGTALPS(ph)ADSCTSPTK ddPTM_HeLa_Curcumin_4h_R1 1 AHSENEGTALPSADSCTSPTK 21 0 F8VZV4;Q8IVL0-3;Q8IVL0-2;Q8IVL0 F8VZV4 NAV3 Neuron navigator 3 1 0 AHSENEGTALPS(0.352)ADS(0.141)CT(0.141)S(0.279)PT(0.087)K 69.981 0.0026293 0 2109.9 1873.4 1887.2 2226.5 2266.9 2570.6 2105.3 1097.8 2145.8 2095.1 TRUE FALSE FALSE 1942.899189 2035.328348 1957.141292 2217.287333 2239.868698 2037.428583 2164.369052 1432.514166 1910.411109 2167.904569 0.896210662 0.938845915 0.902780187 1.02277903 1.033195248 0.939814701 0.998369155 0.660782853 0.881224725 1 11.08208554 -4.25666716 24.91559107 0.957942663 0.660782726 0.747322031 0.051674483 186.6578949 974499.3346 0.007419609 0.080647186 5.54E-05 4.25666716 -0.297159937 AHSPGLLPGHR ddPTM_HeLa_Curcumin_4h_R1 2 AHSPGLLPGHR 11 0 F5H450 F5H450 FZD10 0 0 ; ; 77.379 0.015056 8955600 17567.1 12374.8 14988.6 18016.5 9784.7 555.95 5351.9 7025.7 12211.8 14355.3 FALSE FALSE TRUE 16176.6455 13444.42257 15544.0907 17941.9525 9668.023843 440.6397032 5502.05991 9167.803588 10872.19609 14854.14561 1.089032377 0.90509565 1.046447982 1.207875092 0.650863678 0.029664426 0.37040568 0.617188213 0.731930087 1 13.858578 -5.551309822 5.005109255 1.040661571 0.339068374 0.728726377 0.179488825 0.052582343 3.39230226 0.021122808 0.044101924 2.81E-06 5.551309822 -0.701593197 S(ph)PSPLGTSVR ddPTM_HeLa_Curcumin_4h_R1 2 SPSPLGTSVR 10 0 G5E9V3;E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;E9PDY7 G5E9V3 PHLDB2 Pleckstrin homology-like domain family B member 2 1 0 S(0.576)PS(0.418)PLGT(0.006)SVR;S(0.519)PS(0.382)PLGT(0.098)S(0.001)VR ; 118.23 0.0048725 42611000 5521.3 5290.3 5162.8 6002.1 4992.7 2844.4 2512.2 1413.53 6389.1 5986.8 TRUE FALSE FALSE 5084.283279 5747.569959 5354.13791 5977.264901 4933.165313 2254.439377 2582.685571 1844.50879 5688.231715 6194.840854 0.820728635 0.927799453 0.864289824 0.964877878 0.796334471 0.363922081 0.416909107 0.297749181 0.918220798 1 12.5968515 -5.330582454 3.276265142 0.912741663 0.35703777 0.953793012 0.054873842 0.047094945 0.989300437 0.010576348 0.026389344 4.67E-06 5.330582454 -0.555703893 down AHT(ph)PTPGIYMGRPTHSGGGGGGGGGGGGGGGGR ddPTM_HeLa_Curcumin_4h_R1 3 AHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGR 33 1 Q13595;Q13595-4;Q13595-3 Q13595 TRA2A Transformer-2 protein homolog alpha 1 0 AHT(0.45)PT(0.45)PGIY(0.09)MGRPT(0.008)HS(0.001)GGGGGGGGGGGGGGGGR;AHT(0.492)PT(0.238)PGIY(0.216)MGRPT(0.052)HS(0.002)GGGGGGGGGGGGGGGGR;AHT(0.806)PT(0.18)PGIY(0.003)MGRPT(0.007)HS(0.005)GGGGGGGGGGGGGGGGR ;; 72.228 0.00012112 83957000 4593.3 4328.06 4040 4352.6 4172.67 5297.9 3792.5 3763.79 5151 4465.8 TRUE FALSE FALSE 4229.735458 4702.158221 4189.725954 4334.590094 4122.913636 4199.05582 3898.907343 4911.352245 4585.948187 4620.986218 0.915331762 1.017565948 0.906673545 0.938022727 0.89221509 0.908692565 0.843739228 1.062836376 0.992417629 1 12.17398507 -6.698415516 24.99985266 0.963217761 0.919963949 0.146700685 0.059224102 111.9116065 44391.46641 0.009192679 0.01300041 2.00E-07 6.698415516 -0.043253812 AHTEEPQAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AHTEEPQAKK 10 1 E7ES68;G5E9D5;Q9BQ52-3;Q9BQ52-4;Q9BQ52 E7ES68 ELAC2 Zinc phosphodiesterase ELAC protein 2 0 1 ; AHTEEPQAK(1)K;AHTEEPQAK(1)K 87.298 0.0058373 4793700 5682.1 5123.4 4844.4 4605.8 4855.2 7574.7 4827.2 5830.1 5914.3 5629.9 FALSE TRUE FALSE 5232.355789 5566.243867 5023.937726 4586.74242 4797.304911 6003.621836 4962.63824 7607.670652 5265.516087 5825.538606 0.898175455 0.955489997 0.862398838 0.787350789 0.823495514 1.030569402 0.851876294 1.305917129 0.903867684 1 12.50817573 -4.254563799 24.96769031 0.926000087 1.305917307 0.710374823 0.076035991 380.0657404 1380118.738 0.0115021 0.152692793 5.56E-05 4.254563799 0.37991722 AHTPT(ph)PGIYMGRPTHSGGGGGGGGGGGGGGGGR ddPTM_HeLa_Curcumin_4h_R1 1 AHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGR 33 1 Q13595;Q13595-4;Q13595-3 Q13595 TRA2A Transformer-2 protein homolog alpha 1 0 AHT(0.097)PT(0.315)PGIY(0.264)MGRPT(0.293)HS(0.031)GGGGGGGGGGGGGGGGR 54.308 0.0096689 29241000 1992.2 1366 1549 1605.3 1768.2 2591.8 1634.7 1491.5 2382 1930.6 TRUE FALSE FALSE 1834.515268 1484.070953 1606.407303 1598.657694 1747.11537 2054.231464 1680.565282 1946.251484 2120.700559 1997.688206 0.918319116 0.742894186 0.804133146 0.800253858 0.874568596 1.028304346 0.841255045 0.974251877 1.061577354 1 10.96411571 -8.045516292 1.462749719 0.97927173 0.868190978 0.327896548 0.084457425 0.365541966 1.60611824 0.019900146 0.016808935 9.00E-09 8.045516292 -0.111080752 AHVDEFK ddPTM_HeLa_Curcumin_4h_R1 1 AHVDEFK 7 0 A0A087WYS1;E7EUC7;Q16851-2;Q16851 A0A087WYS1 UGP2 UTP--glucose-1-phosphate uridylyltransferase 0 0 107.32 0.013382 3803000 4162.5 3145.6 3151.3 2797.6 3504.6 4410.6 3342.4 3425.8 3272.7 3292.2 FALSE FALSE TRUE 3833.033733 3417.491647 3268.08995 2786.024272 3462.809934 3495.791842 3436.178748 4470.31065 2913.692998 3406.603705 1.125177468 1.003196128 0.959339634 0.817830459 1.016499198 1.026180955 1.00868168 1.312248514 0.855307294 1 11.73411841 -4.259233989 24.13126274 1.026190413 1.312248677 0.474597883 0.094073125 84.5425377 924953.3437 0.012719851 0.11162256 5.51E-05 4.259233989 0.286058264 AIACLLFGGSR ddPTM_HeLa_Curcumin_4h_R1 2 AIACLLFGGSR 11 0 B1AHB1;P33992 B1AHB1 MCM5 DNA helicase;DNA replication licensing factor MCM5 0 0 ; ; 114.5 0.0031226 1329490 104.48 0 50.605 201.195 63.004 257.36 66.364 0 0 110.23 FALSE FALSE TRUE 96.21029775 0 52.48046582 200.3625084 62.25271845 203.980635 68.22599523 0 0 114.0604843 0.843502448 0 0.460110845 1.756633856 0.545786903 1.788354979 0.598156282 0 0 1 6.833655253 -13.51001219 0.029283987 2.129668572 1.10E-05 0 0.657356446 5862.781186 13.82095087 755.4216425 331.2835226 3.09E-14 13.51001219 -2.129657563 AIANECQANFISIK ddPTM_HeLa_Curcumin_4h_R1 2 AIANECQANFISIK 14 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 ; ; 263.44 8.59E-77 2512900 545.71 676.16 845.03 568.15 763.18 985.67 808.55 662.99 707.82 751.33 FALSE FALSE TRUE 502.5164777 734.6042575 876.3475552 565.7991458 754.0795769 781.2309312 831.2357369 865.132599 630.1739169 777.4386616 0.646374438 0.944903172 1.127224048 0.727773359 0.969953791 1.004877902 1.069197839 1.112798529 0.810577024 1 9.602585044 -4.979686624 0.728826377 0.84925259 1.165683499 0.287969867 0.130266157 1.473714648 0.950265165 0.028777649 0.312783266 1.05E-05 4.979686624 0.316430909 AIAVDPIAGK ddPTM_HeLa_Curcumin_4h_R1 2 AIAVDPIAGK 10 0 Q9NZR2 Q9NZR2 LRP1B Low-density lipoprotein receptor-related protein 1B 0 0 ; ; 112.17 0.0047053 6991300 5279.2 4893.1 4826 4907.6 4970.1 6555.9 5644.9 5141 5929.1 4878.2 FALSE FALSE TRUE 4861.345749 5316.037761 5004.855805 4887.293652 4910.834804 5196.13244 5803.280702 6708.467234 5278.692564 5047.717087 0.963078094 1.053156837 0.991508779 0.968218616 0.972882338 1.029402471 1.149684224 1.329010148 1.045758404 1 12.30141534 -4.404804122 1.571135296 0.98635025 1.403016981 0.916365579 0.030924667 0.126617155 0.358362818 0.003869567 0.073962434 3.94E-05 4.404804122 0.416666731 AIDLFTDAIK ddPTM_HeLa_Curcumin_4h_R1 1 AIDLFTDAIK 10 0 P50502;Q3KNR6;Q8NFI4;H7C3I1;F6VDH7;Q8IZP2 P50502 ST13;ST13P5;ST13P4 Hsc70-interacting protein;Putative protein FAM10A5;Putative protein FAM10A4 0 0 131.44 3.49E-11 0 726.44 324 476.35 527.31 395.76 558.4 527.14 362.92 560.6 547.88 FALSE FALSE TRUE 668.9415075 352.0051163 494.00395 525.1281309 391.0408205 442.5815455 541.9301297 473.5726373 499.1035826 566.9187892 1.179960023 0.620909243 0.871383979 0.926284577 0.689765144 0.780678915 0.955921977 0.835344755 0.880379328 1 9.146998275 -7.275425656 24.97925104 1.084981124 0.817880778 0.345566558 0.12193213 424.412099 757991.1342 0.019265688 0.022089075 5.30E-08 7.275425656 -0.267100346 AIDS(ph)PGGAVR ddPTM_HeLa_Curcumin_4h_R1 2 AIDSPGGAVR 10 0 O60346 O60346 PHLPP1 PH domain leucine-rich repeat-containing protein phosphatase 1 1 0 AIDS(1)PGGAVR;AIDS(1)PGGAVR ; 129 0.0030611 19494200 4012.5 3427.1 3279.9 3464.5 3522.9 5343 3323.3 4449.16 4214 3424.3 TRUE FALSE FALSE 3694.906391 3723.323253 3401.455979 3450.164817 3480.891718 4234.801572 3416.542854 5805.688403 3751.734743 3543.29417 1.042788494 1.050808393 0.959969965 0.973716731 0.982388577 1.195159467 0.964227831 1.638500255 1.058826776 1 11.79087553 -4.258183172 24.99952587 1.021850812 1.638500484 0.884482167 0.06646903 67.4882691 518116.2257 0.008521139 0.081660352 5.52E-05 4.258183172 0.616649672 AIEEGTLEEIEEEVR ddPTM_HeLa_Curcumin_4h_R1 2 AIEEGTLEEIEEEVR 15 0 P51532;P51532-4;P51532-3;P51532-2;P51532-5;A0A0A0MT49;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8Y440;A0A2R8Y4C5;A0A2R8Y6N0;A0A2R8YG32;A0A2R8Y7F3;A0A2R8YF80;A0A2R8YF58;A0A2R8Y526;A0A2R8Y7Y7;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;K7EP28 P51532 SMARCA4 Transcription activator BRG1 0 0 ; ; 204.48 1.57E-08 4425200 1052.74 881.78 927.01 1070.35 1375.43 1246.39 1057.58 874.71 1211.82 1193.56 FALSE FALSE TRUE 969.4145182 957.9971341 961.3658061 1065.921175 1359.028896 987.8746643 1087.252848 1141.405052 1078.886378 1235.036121 0.784928069 0.775683494 0.778411084 0.863068826 1.100396071 0.799875119 0.880340931 0.924187587 0.873566659 1 10.27033752 -4.257464196 19.82540575 0.883991107 0.924187805 0.012390196 0.100307314 132.650343 660958.4988 0.015992484 0.152509805 5.53E-05 4.257464196 0.040196698 AIEINPDSAQPYK ddPTM_HeLa_Curcumin_4h_R1 2 AIEINPDSAQPYK 13 0 P50502;Q3KNR6;Q8NFI4;H7C3I1;F6VDH7;Q8IZP2 P50502 ST13;ST13P5;ST13P4 Hsc70-interacting protein;Putative protein FAM10A5;Putative protein FAM10A4 0 0 ; ; 221.55 5.90E-71 7161300 4172.8 3639.3 3852.9 3413.1 3963 4338.1 3677.6 3727.4 4217.6 3537.2 FALSE FALSE TRUE 3842.518477 3953.864876 3995.691863 3398.977497 3915.743813 3438.32916 3780.783558 4863.867101 3754.939832 3660.117437 1.049834751 1.080256288 1.09168406 0.928652579 1.069841031 0.939404054 1.032967828 1.328882798 1.025906927 1 11.83767422 -4.262771528 6.365111926 1.02368684 1.335340743 0.753469685 0.052293663 0.042449471 9.77008567 0.006927071 0.057099121 5.46E-05 4.262771528 0.311653903 AIENLIGK(ac)PTEK ddPTM_HeLa_Curcumin_4h_R1 2 AIENLIGKPTEK 12 1 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 0 1 ; AIENLIGK(1)PTEK;AIENLIGK(1)PTEK 164.48 3.01E-06 3676800 4206.4 3483.3 3631.2 3944.6 4059 4078.4 3832.7 3565.7 3778.2 3241.7 FALSE TRUE FALSE 3873.459001 3784.380931 3765.775466 3928.27829 4010.599076 3232.493867 3940.235247 4652.865516 3363.740913 3354.348834 1.154757359 1.128201364 1.122654695 1.171100111 1.195641621 0.963672542 1.174664724 1.387114384 1.002799971 1 11.71181701 -13.52287875 0.142361258 0.435906345 1.220006393 0.354804562 0.093506152 68.80581501 0.678246299 10.96311839 0.261611851 3.00E-14 13.52287875 0.784100047 AIENLIGKPTEK(ac)SQTPK ddPTM_HeLa_Curcumin_4h_R1 1 AIENLIGKPTEKSQTPK 17 2 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 0 1 AIENLIGKPTEK(1)SQTPK 132.81 0.00021363 1620500 495.31 508.36 483.91 356.98 547.76 648.28 544.53 509.73 414.94 492.45 FALSE TRUE FALSE 456.1056909 552.3003732 501.8441303 355.5029113 541.2283198 513.8194204 559.8080463 665.1443305 369.4221201 509.5626008 0.895092556 1.083871486 0.984852753 0.697662879 1.062142942 1.00835387 1.098605049 1.305324075 0.724978873 1 8.993115585 -4.188005057 1.165914831 0.949877949 1.514249029 0.481241439 0.122708052 1.054554529 1.043391782 0.014864735 0.751086227 6.49E-05 4.188005057 0.56437108 AIEPPPLDAVIEAEHTLR ddPTM_HeLa_Curcumin_4h_R1 2 AIEPPPLDAVIEAEHTLR 18 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 0 ; ; 263.04 1.39E-53 9513600 7611.7 6688.4 6853.1 6897.1 6600.9 8920.2 6585.1 5885.6 8166 7587.1 FALSE FALSE TRUE 7009.225913 7266.515493 7107.081915 6868.561628 6522.188579 7070.049969 6769.860183 7680.092346 7270.21023 7850.75116 0.892809589 0.925582195 0.905274128 0.874892286 0.830772552 0.900557135 0.862320056 0.978262104 0.926052817 1 12.93861498 -9.285812726 0.532732986 1.022031545 0.889593852 0.195821864 0.043424784 0.849433446 0.329649829 0.058051434 0.009022404 5.18E-10 9.285812726 -0.132437693 AIEQADLLQEEDES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 AIEQADLLQEEDESPR 16 0 A0A2R8YGH5;H7C1E4;P61966 A0A2R8YGH5 AP1S1 AP-1 complex subunit sigma-1A 1 0 AIEQADLLQEEDES(1)PR;AIEQADLLQEEDES(1)PR ; 199.41 5.26E-08 9523300 2911.4 3241.6 2982.2 2729.5 3646.4 3043.9 2725.8 2372 2880.1 2888.9 TRUE FALSE FALSE 2680.959618 3521.78946 3092.722955 2718.206052 3602.919062 2412.560828 2802.278612 3095.211881 2564.160236 2989.28906 0.89685526 1.178136135 1.034601503 0.909315224 1.205276234 0.80706843 0.937439825 1.035434118 0.857782631 1 11.54558669 -3.648288504 4.487313696 0.975107684 3.330515481 0.015448335 0.123390645 1366.361411 543.1103093 0.015885392 31390.373 0.000224756 3.648288504 2.355407797 AIESLVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AIESLVKK 8 1 K7ENG1;K7EL15;K7EL18;K7EIJ2;K7ES96;K7EIU8;Q13485 K7ENG1 SMAD4 Mothers against decapentaplegic homolog;Mothers against decapentaplegic homolog 4 0 1 ; AIESLVK(1)K;AIESLVK(1)K 101.64 0.0040152 4549200 6219.8 5663.3 5597 6016.7 5473.1 6023.5 4598.6 4522.2 7177.1 5895.4 FALSE TRUE FALSE 5727.496267 6152.810417 5804.429744 5991.80449 5407.836857 4774.158201 4727.62434 5900.997962 6389.790086 6100.264711 0.938893071 1.008613676 0.951504569 0.982220407 0.886492163 0.782614924 0.774986753 0.967334737 1.047461117 1 12.57465613 -5.60885123 3.860082396 0.972581479 0.834523762 0.565934435 0.057821318 0.115961606 3.337565153 0.007566577 0.015875827 2.46E-06 5.60885123 -0.138057717 AIGGIILTAS(ph)HNPGGPNGDFGIK ddPTM_HeLa_Curcumin_4h_R1 5 AIGGIILTASHNPGGPNGDFGIK 23 0 A0A3B3ITK7;P36871;P36871-2 A0A3B3ITK7 PGM1 Phosphoglucomutase-1 1 0 AIGGIILT(0.002)AS(0.998)HNPGGPNGDFGIK;AIGGIILT(0.119)AS(0.881)HNPGGPNGDFGIK;AIGGIILT(0.004)AS(0.996)HNPGGPNGDFGIK;AIGGIILT(0.025)AS(0.975)HNPGGPNGDFGIK;AIGGIILT(0.221)AS(0.779)HNPGGPNGDFGIK ;;;; 166.36 3.82E-09 5811215000 9166.45 8213.71 9052.33 8702.94 8616.06 11500.21 9557.6 8915.39 8264.11 9556.27 TRUE FALSE FALSE 8440.91581 8923.666493 9387.817313 8666.92954 8513.319112 9114.936812 9825.760533 11633.65137 7357.557809 9888.349671 0.853622302 0.902442449 0.949381608 0.876478869 0.860944384 0.921785446 0.993670416 1.176500807 0.744063272 1 13.27151405 -4.295354258 2.250412938 0.919453474 1.230508359 0.595179158 0.069382107 0.278319143 1.709092703 0.008431138 0.166027419 5.07E-05 4.295354258 0.311054885 AIGNNSAT(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 AIGNNSATSPR 11 0 A0A1B0GV57;Q9NYJ8-2;Q9NYJ8 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 0 AIGNNS(0.008)AT(0.672)S(0.32)PR 111.94 0.017394 3541500 2381.8 1509.5 2256.6 2385.8 2311.3 1930 1605.7 2702.8 1707.8 1745.7 TRUE FALSE FALSE 2193.278017 1639.974454 2340.231581 2375.928192 2283.739257 1529.696244 1650.75162 3526.871278 1520.458613 1806.362945 1.214195643 0.907887564 1.29554893 1.315310524 1.264274859 0.846837701 0.913853788 1.952471007 0.841723761 1 10.81887208 -4.253621365 24.98195777 1.10194202 1.952471421 0.672687589 0.183896951 424.8458823 1357535.487 0.023828818 0.345262747 5.58E-05 4.253621365 0.850529402 AIGSS(ph)PLGSGEGLLGLS(ph)PGPNGHSHLLK ddPTM_HeLa_Curcumin_4h_R1 1 AIGSSPLGSGEGLLGLSPGPNGHSHLLK 28 0 A0A087WZ13;E9PAU2;Q8IY67-2;Q8IY67;K7EQG2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 2 0 AIGS(0.407)S(0.446)PLGS(0.168)GEGLLGLS(0.971)PGPNGHS(0.007)HLLK 47.989 0.010113 7179000 839.36 613.27 762.62 705.88 883.41 1879.4 1162.8 497.36 1013.4 596.73 TRUE FALSE FALSE 772.9237703 666.2783261 790.8833681 702.9592556 872.8759127 1489.591255 1195.425038 649.0027744 902.2325554 617.4663231 1.251766682 1.07905209 1.280852637 1.138457644 1.413641328 2.412425098 1.936016579 1.051073962 1.461185042 1 9.270216643 -5.504448057 9.117023053 1.138536178 1.830444621 0.381221493 0.334247839 0.172537739 77.97113415 0.044574455 0.096179955 3.13E-06 5.504448057 0.691908444 AIGSVPERS(ph)PAGVDLSLTGLPPPVSR ddPTM_HeLa_Curcumin_4h_R1 2 AIGSVPERSPAGVDLSLTGLPPPVSR 26 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 0 AIGSVPERS(0.996)PAGVDLS(0.003)LTGLPPPVSR;AIGS(0.022)VPERS(0.978)PAGVDLSLTGLPPPVSR ; 97.825 2.40E-06 43678000 2087.55 1425.81 1775.82 1756.01 1720.27 2521.82 1885.22 941.76 1938.02 1906.68 TRUE FALSE FALSE 1922.318215 1549.050663 1841.633451 1748.744096 1699.756904 1998.766105 1938.114199 1228.898289 1725.424055 1972.936988 0.974343441 0.785149588 0.933447679 0.886365914 0.861536336 1.013091709 0.982349771 0.622877617 0.874545951 1 10.94612916 -1 0.143994217 1.028851793 0.282152857 0.065041496 0.109429311 79.62289786 0.751116639 0.25083017 12.35942293 0.1 1 -0.746698936 AIGVKPPR ddPTM_HeLa_Curcumin_4h_R1 1 AIGVKPPR 8 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 87.754 0.013594 5139700 2038.9 1604.8 1604.6 1676 1938.7 2536.9 1666.6 1661.9 2103.6 1726.1 FALSE FALSE TRUE 1877.518914 1743.511761 1664.067888 1669.065156 1915.582269 2010.718343 1713.360311 2168.60566 1872.840343 1786.081847 1.05119422 0.976165658 0.931686244 0.934484139 1.072505312 1.12577055 0.959284321 1.214169252 1.04857476 1 10.80258248 -4.250905677 24.29468187 1.016029943 1.214169419 0.503712478 0.060297536 682.6186106 1574329.816 0.008473639 0.157661331 5.61E-05 4.250905677 0.198139477 AIIEEYLHLNDMK ddPTM_HeLa_Curcumin_4h_R1 1 AIIEEYLHLNDMK 13 0 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 0 118.37 0.0016551 0 1399.5 1238 1374.8 1266.2 1592.6 2203.6 1727.3 1287.6 1275.9 1322.5 FALSE FALSE TRUE 1288.728098 1345.007204 1425.751297 1260.9608 1573.609285 1746.54852 1775.763389 1680.183313 1135.936962 1368.456777 0.941738256 0.982864221 1.04186798 0.921447299 1.149915227 1.2762906 1.29763937 1.227794214 0.83008611 1 10.41833415 -5.556745466 3.382453304 0.97540813 1.267201481 0.85524452 0.058315931 0.043591133 1.036474331 0.005584718 0.012273754 2.77E-06 5.556745466 0.291793351 AIK(ac)LRPIAVIKG ddPTM_HeLa_Curcumin_4h_R1 2 AIKLRPIAVIKG 12 3 Q9Y3I0 Q9Y3I0 RTCB tRNA-splicing ligase RtcB homolog 0 1 ; AIK(1)LRPIAVIKG;AIK(1)LRPIAVIKG 98.754 0.00050567 0 3240.2 2583.73 2519.1 2702.1 2512.7 5644.4 3588.3 3646.4 3348.8 2358.3 FALSE TRUE FALSE 2983.734751 2807.056108 2612.460062 2690.919426 2482.737694 4473.687815 3688.978041 4758.170574 2981.445018 2440.250749 1.222716457 1.150314618 1.070570335 1.102722508 1.017410893 1.833290212 1.511720892 1.949869527 1.221778139 1 11.25281369 -5.26187998 24.99998961 1.102991509 1.739636304 0.85233268 0.124330553 10.50550824 596113.2335 0.017585575 0.041722166 5.47E-06 5.26187998 0.636644795 AIKVEQATK(ac)PSFESGR ddPTM_HeLa_Curcumin_4h_R1 1 AIKVEQATKPSFESGR 16 2 P38159;P38159-2;H0Y6E7;H3BT71 P38159 RBMX "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed" 0 1 AIKVEQATK(1)PSFESGR 127.18 0.00020976 2744800 596.73 600.16 604.85 411.85 554.41 1035.4 731.04 852.25 1238.6 452.47 FALSE TRUE FALSE 549.4981908 652.0351561 627.2662731 410.1458738 547.7990228 820.6463686 751.5510149 1112.097102 1102.728679 468.1932988 1.173656676 1.392662299 1.339759186 0.876018249 1.170027474 1.752793922 1.605215232 2.375294786 2.355285053 1 8.870960475 -1 0.50911353 1.093173382 44.16819592 0.212624981 0.44050018 30.84028366 0.289153208 0.037404181 1435.503027 0.1 1 43.07502254 AAS(ph)ADYLRPR ddPTM_HeLa_Curcumin_4h_R1 1 AASADYLRPR 10 1 B1AKL4;Q9NRA8;Q9NRA8-3;Q9NRA8-2;B0QYZ7 B1AKL4 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 0 AAS(0.981)ADY(0.019)LRPR 85.924 0.010731 4734500 2810.9 2314.2 2632.4 2585.7 1756.5 1773.2 711.59 575.94 3415.7 2523.9 TRUE FALSE FALSE 2588.414299 2514.229136 2729.95906 2575.001059 1735.554885 1405.418332 731.5553003 751.5414547 3041.006256 2611.605337 0.991120007 0.962714044 1.04531838 0.985983993 0.664554809 0.53814346 0.280117095 0.287769918 1.164420294 1 11.35072118 -5.310997572 1.315951224 1.00005965 0.26584674 0.947146624 0.070841253 0.047788034 0.151656318 0.006964253 0.027575424 4.89E-06 5.310997572 -0.73421291 down LIES(ph)PFER ddPTM_HeLa_Curcumin_4h_R1 3 LIESPFER 8 0 E9PDC2;A0A088AWP5;Q8WUY3-4;Q8WUY3;Q8WUY3-2;Q8WUY3-3;H7BZH9 E9PDC2 PRUNE2 Protein prune homolog 2 1 0 LIES(1)PFER;LIES(1)PFER;LIES(1)PFER ;; 122.94 0.0073567 92002000 11545.6 9952.6 9701.9 9768.6 9124.4 7501.6 4804.6 3776.91 12279.5 10037.5 TRUE FALSE FALSE 10631.75358 10812.8584 10061.46095 9728.180122 9015.597489 5945.6836 4939.404145 4928.472472 10932.46957 10386.30238 1.023632202 1.041069093 0.968724054 0.936635558 0.868027635 0.572454314 0.475569068 0.47451656 1.052585335 1 13.34239451 -5.306052724 1.477653379 1.010020342 0.452426544 0.985438252 0.027240559 0.030030636 0.122427758 0.003739762 0.013598373 4.94E-06 5.306052724 -0.557593798 down AILGSYDSELTPAEYS(ph)PQLTR ddPTM_HeLa_Curcumin_4h_R1 3 AILGSYDSELTPAEYSPQLTR 21 0 C9J9H5;C9JX80;Q9Y6D9-3;Q9Y6D9 C9J9H5;Q9Y6D9-3 MAD1L1 Mitotic spindle assembly checkpoint protein MAD1 1 0 AILGSYDSELT(0.002)PAEY(0.214)S(0.692)PQLT(0.093)R;AILGSYDSELT(0.037)PAEY(0.018)S(0.838)PQLT(0.106)R;AILGSYDSELTPAEY(0.005)S(0.973)PQLT(0.022)R ;; 141.69 6.01E-06 16649000 6480.4 5913.8 5700.3 5687.8 6599.1 9195.2 7787.6 5239.1 6629.8 5454.7 TRUE FALSE FALSE 5967.469502 6424.962521 5911.558132 5664.265391 6520.410043 7288.011869 8006.099097 6836.477472 5902.527527 5644.250419 1.057265192 1.138319891 1.047359294 1.003546081 1.155230466 1.291227591 1.418452142 1.211228589 1.045759328 1 12.46256628 -5.422095669 2.58549942 1.037326169 1.322006969 0.784909021 0.060138045 0.087420199 1.132467946 0.008845206 0.022255851 3.78E-06 5.422095669 0.2846808 AILGSYDSELTPAEYS(ph)PQLTRR ddPTM_HeLa_Curcumin_4h_R1 1 AILGSYDSELTPAEYSPQLTRR 22 1 C9J9H5;C9JX80;Q9Y6D9-3;Q9Y6D9 C9J9H5;Q9Y6D9-3 MAD1L1 Mitotic spindle assembly checkpoint protein MAD1 1 0 AILGSYDSELTPAEY(0.15)S(0.805)PQLT(0.045)RR 86.213 0.00025445 10978000 2209.7 1641.3 1448.8 1741.9 1335.9 2730.7 1517.9 1550 2423.8 2051.2 TRUE FALSE FALSE 2034.799913 1783.166659 1502.493802 1734.692479 1319.970265 2164.322039 1560.488189 2022.587865 2157.915204 2122.479047 0.958690224 0.840133928 0.707895705 0.817295455 0.621900257 1.019714207 0.735219597 0.952936552 1.016695645 1 11.0515346 -7.25432879 3.241671898 0.98224925 0.805059355 0.364015446 0.108516199 0.188048858 4.031875037 0.017313105 0.020565273 5.57E-08 7.25432879 -0.177189894 AILGSYDSELTPAEYSPQLT(ph)RR ddPTM_HeLa_Curcumin_4h_R1 1 AILGSYDSELTPAEYSPQLTRR 22 1 C9J9H5;C9JX80;Q9Y6D9-3;Q9Y6D9 C9J9H5;Q9Y6D9-3 MAD1L1 Mitotic spindle assembly checkpoint protein MAD1 1 0 AILGSYDSELTPAEY(0.09)S(0.09)PQLT(0.819)RR 68.567 0.0014188 8838800 1480.1 1248.1 1019.1 1101.4 671.73 1431.1 1136.8 1068.5 1840.9 1381.8 TRUE FALSE FALSE 1362.948523 1355.980203 1056.868742 1096.842699 663.7200585 1134.273728 1168.695548 1394.280731 1638.957876 1429.817447 0.953232544 0.948358971 0.739163412 0.767120796 0.46419916 0.793299683 0.81737396 0.975145977 1.146270721 1 10.48161525 -6.802713242 4.832984557 0.976399013 0.749925651 0.466135691 0.130184628 0.138334701 7.285320465 0.019540276 0.026310761 1.58E-07 6.802713242 -0.226473362 AILILDNDGDR ddPTM_HeLa_Curcumin_4h_R1 1 AILILDNDGDR 11 0 F8VXB1;F8VUC5;F8W156;F8W651;F8VXR1;F8VYZ4;F8VVA7;P61923-5;P61923;P61923-4 F8VXB1 COPZ1 Coatomer subunit zeta-1 0 0 188.91 0.0003891 10612000 3868.4 3226.6 3728.4 3861.4 3833.4 4248.2 3943.2 3489.3 3505.3 3314.4 FALSE FALSE TRUE 3562.212058 3505.492927 3866.577784 3845.42255 3787.689209 3367.075433 4053.835579 4553.171507 3120.77736 3429.575153 1.038674442 1.022136203 1.127421797 1.121253327 1.104419364 0.98177625 1.18202267 1.327619692 0.909960336 1 11.74381415 -1 0.646659907 1.030612221 26.90078863 0.643914295 0.067053127 82.80652018 0.501461301 0.010060013 3071.019459 0.1 1 25.87017641 AILILDNDGDRLFAK ddPTM_HeLa_Curcumin_4h_R1 2 AILILDNDGDRLFAK 15 1 F8VXB1;F8VUC5;F8W156;F8W651;F8VXR1;F8VYZ4;F8VVA7;P61923-5;P61923;P61923-4 F8VXB1 COPZ1 Coatomer subunit zeta-1 0 0 ; ; 152 0.00036548 15110200 4544.8 3222.2 3484.3 3730.1 2697.4 4186.6 3139 3100.4 4623 4042.3 FALSE FALSE TRUE 4185.074284 3500.71261 3613.431223 3714.665835 2665.235267 3318.251967 3227.071892 4045.697688 4115.868466 4182.769624 1.000550989 0.83693651 0.863884829 0.888087599 0.637193895 0.793314542 0.77151557 0.967229384 0.984005536 1 12.03024283 -7.111780196 1.559022612 1.003192434 0.805461152 0.470663946 0.082135807 0.206014568 0.963368294 0.014830856 0.018683646 7.73E-08 7.111780196 -0.197731282 AILSCMGYT(ph)PELGT(ph)AY(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 AILSCMGYTPELGTAYK 17 0 Q9UM82 Q9UM82 SPATA2 Spermatogenesis-associated protein 2 3 0 AILS(0.004)CMGY(0.044)T(0.957)PELGT(0.996)AY(1)K 50.358 0.015762 8560100 1538.8 1506.6 1592.4 1282.3 1345.8 2027.1 1132.9 1062.6 1587 1237.3 TRUE FALSE FALSE 1417.002356 1636.823791 1651.415745 1276.994182 1329.752214 1606.65661 1164.686125 1386.581848 1412.91007 1280.296083 1.106777077 1.278472857 1.289870185 0.997420987 1.038628667 1.254910197 0.909700608 1.083016551 1.103580718 1 10.32226177 -1.585706337 14.46653585 1.081985173 2.216606515 0 0.125794734 0 0 0.017092759 0 0.025959341 1.585706337 1.134621343 AILVDLEPGTMDSVR ddPTM_HeLa_Curcumin_4h_R1 2 AILVDLEPGTMDSVR 15 0 Q5JP53;P07437;G3V5W4;G3V2R8;G3V3R4;G3V2N6;Q9BVA1;Q13885;A0A0B4J269;Q13509 Q5JP53;Q9BVA1;A0A0B4J269 TUBB;TUBB3;TUBB2B;TUBB2A Tubulin beta chain;Tubulin beta-2B chain;Tubulin beta-2A chain;Tubulin beta-3 chain 0 0 ; ; 143.79 0.0014773 2299200 649.19 597.06 699.63 637.86 670.36 682.56 529.73 734.81 725.07 540.21 FALSE FALSE TRUE 597.8059265 648.667206 725.5589033 635.2207043 662.3663948 540.989362 544.5927981 958.8501864 645.531635 558.9822573 1.069454207 1.160443283 1.297999881 1.136387955 1.18495066 0.96781133 0.974257753 1.715349949 1.154833855 1 9.126658681 -4.256270276 24.92785109 1.069388688 1.715350228 0.746538487 0.104824158 201.8230175 973253.022 0.015623956 0.17628138 5.54E-05 4.256270276 0.64596154 AILVVFANK ddPTM_HeLa_Curcumin_4h_R1 2 AILVVFANK 9 0 B4DZG7;F8VYN9;P40616-2;P40616 B4DZG7 ARL1 ADP-ribosylation factor-like protein 1 0 0 ; ; 94.407 0.015783 927170 957.51 588.55 708.07 905.13 982.52 84.98 281.179 495.14 856.23 957.17 FALSE FALSE TRUE 881.7220731 639.4216395 734.3116971 901.3848119 970.8040907 67.35419008 289.068126 646.1059067 762.3037112 990.4315863 0.89024026 0.645598998 0.741405774 0.910092958 0.980182886 0.068004889 0.291860771 0.652347841 0.769668215 1 9.951913515 -5.273500634 24.97837595 0.906793553 0.332850124 0.633772767 0.173965346 296.32239 613671.7613 0.02514207 0.05661838 5.33E-06 5.273500634 -0.573943429 AIMTYVSSFYHAFSGAQK ddPTM_HeLa_Curcumin_4h_R1 1 AIMTYVSSFYHAFSGAQK 18 0 O43707;P12814-4;P12814-3;P12814;P12814-2;H9KV75;G3V2N5;G3V2W4 O43707;P12814-4 ACTN4;ACTN1 Alpha-actinin-4;Alpha-actinin-1 0 0 112.12 0.00018544 1641400 252.8 128.87 342.75 170.3 277.78 1462.4 373.21 432.03 196.77 221.38 FALSE FALSE TRUE 232.7906132 140.0089486 355.4526165 169.5953437 274.4676549 1159.081755 383.6812682 563.7539582 175.1848233 229.0729385 1.016229218 0.611198117 1.551700602 0.740355211 1.198167085 5.059880765 1.674930573 2.46102382 0.764755647 1 7.839663226 -5.484561996 24.88419521 1.002065994 2.960041071 0.569285554 0.830044785 270.6294247 175755.6802 0.106158891 0.237328313 3.28E-06 5.484561996 1.957975076 AINGPTSAS(ph)GDDISK ddPTM_HeLa_Curcumin_4h_R1 2 AINGPTSASGDDISK 15 0 B4DXZ6;P51114-3;P51114;H7C4S4 B4DXZ6 FXR1 Fragile X mental retardation syndrome-related protein 1 1 0 AINGPTS(0.008)AS(0.992)GDDISK;AINGPTS(0.009)AS(0.773)GDDIS(0.218)K ; 202.34 2.30E-09 22512000 6116.2 5106.5 5318.1 5469.4 6428 6288.1 4758.9 4689.3 6055.7 6053.9 TRUE FALSE FALSE 5632.096316 5547.883106 5515.193464 5446.769072 6351.350298 4983.877179 4892.421926 6119.045983 5391.404861 6264.272574 0.899082256 0.885638842 0.880420416 0.869497457 1.013900692 0.795603499 0.781003998 0.976816687 0.860659366 1 12.61293127 -9.435082906 0.353815716 1.05244447 0.873105341 0 0.079905397 3.068919546 0.457572497 0.218245524 0.027644698 3.67E-10 9.435082906 -0.179339129 AINGPTSASGDDIS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 AINGPTSASGDDISK 15 0 B4DXZ6;P51114-3;P51114;H7C4S4 B4DXZ6 FXR1 Fragile X mental retardation syndrome-related protein 1 1 0 AINGPTSAS(0.002)GDDIS(0.998)K 225.29 1.16E-20 6876700 2086.3 1898.8 1976.7 2021.3 1657.4 2214 1533.3 1476.7 2217.4 1867 TRUE FALSE FALSE 1921.167154 2062.923811 2049.958241 2012.936396 1637.636587 1754.791443 1576.320271 1926.939032 1974.156768 1931.878111 0.994455676 1.067833317 1.061121936 1.041958281 0.847691466 0.908334451 0.81595224 0.99744338 1.021884743 1 10.91578836 -5.764173505 24.99999999 1.011289545 0.888039372 0.624472184 0.051332039 37.90927758 346635.6059 0.007356694 0.013780382 1.72E-06 5.764173505 -0.123250173 AINQGGLTSVAVR ddPTM_HeLa_Curcumin_4h_R1 1 AINQGGLTSVAVR 13 0 G3V5Z7;P60900-2;P60900;G3V295;G3V3U4;G3V3I1 G3V5Z7 PSMA6 Proteasome subunit alpha type;Proteasome subunit alpha type-6 0 0 92.943 0.015423 1917500 228.44 247.76 136.86 149.34 370.96 192.82 337.62 244.77 352.67 69.167 FALSE FALSE TRUE 210.358733 269.1752704 141.932152 148.7220706 366.5365443 152.8269585 347.0927085 319.3992462 313.9829833 71.5705481 2.939180131 3.760978189 1.983108356 2.077978646 5.121332084 2.135333074 4.849658383 4.462719019 4.38704176 1 6.161294123 -7.091455236 0.153694955 4.60E-18 5.619330609 0 1.394231568 2.92799244 0.373537174 5.555916163 6.658790603 8.10E-08 7.091455236 5.619330609 AIPELDAYEAEGLALDDEDVEELTAS(ph)QR ddPTM_HeLa_Curcumin_4h_R1 1 AIPELDAYEAEGLALDDEDVEELTASQR 28 0 P49736;F8WDM3;C9J013;C9JZ21;H7C4N9 P49736 MCM2 DNA replication licensing factor MCM2 1 0 AIPELDAYEAEGLALDDEDVEELT(0.325)AS(0.675)QR 114.76 8.73E-11 3654200 400.95 300.77 388.69 270.02 393.88 362.35 478.49 565.71 284.11 393.85 TRUE FALSE FALSE 369.2143844 326.7672186 403.0951933 268.9027288 389.1832383 287.1945255 491.9151416 738.1923748 252.9438438 407.5362582 0.905966959 0.801811402 0.989102651 0.659825288 0.954965921 0.704709139 1.207046322 1.811353861 0.620665864 1 8.67078461 -4.3588366 2.962121962 0.911798608 1.872866821 0.790473002 0.15087203 0.087607213 1.190142384 0.016711641 0.174554144 4.38E-05 4.3588366 0.961068214 AIPGDQHPES(ph)PVHTEPMGIQGR ddPTM_HeLa_Curcumin_4h_R1 6 AIPGDQHPESPVHTEPMGIQGR 22 0 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 AIPGDQHPES(0.979)PVHT(0.021)EPMGIQGR;AIPGDQHPES(0.975)PVHT(0.025)EPMGIQGR;AIPGDQHPES(1)PVHTEPMGIQGR;AIPGDQHPES(1)PVHTEPMGIQGR;AIPGDQHPES(1)PVHTEPMGIQGR;AIPGDQHPES(1)PVHTEPMGIQGR ;;;;; 156.02 6.28E-07 234083000 10440.1 7425.02 9275.4 11291.2 9544 11882.6 9758.4 7140.4 12686.1 9184.8 TRUE FALSE FALSE 9613.755069 8066.805644 9619.154483 11244.48001 9430.194033 9418.014815 10032.19444 9317.47509 11294.46657 9503.971116 1.011551377 0.848782635 1.012119499 1.183134909 0.992237236 0.990955749 1.055579222 0.980377042 1.188394454 1 13.21431474 -6.516957659 24.99824741 0.9908375 1.042043954 0.001861788 0.094183191 480.5375955 2028786.037 0.011053459 0.015937296 3.04E-07 6.516957659 0.051206454 AIPNGFGTS(ph)PLTPSAR ddPTM_HeLa_Curcumin_4h_R1 1 AIPNGFGTSPLTPSAR 16 0 J3QSD2;J3QRZ1;A6NIZ0;Q9GZM8-3;Q9GZM8;Q9GZM8-2 J3QSD2 NDEL1 Nuclear distribution protein nudE-like 1 1 0 AIPNGFGT(0.08)S(0.906)PLT(0.014)PSAR 89.136 0.00636 11735000 393.37 339.16 464.87 607.39 536.33 498.97 308.56 393.32 551.03 514.71 TRUE FALSE FALSE 362.2343494 368.4754791 482.0984911 604.8767811 529.934615 395.4779974 317.2173632 513.2414574 490.5833876 532.5961342 0.680129513 0.691847829 0.905185863 1.135713803 0.995002744 0.74254763 0.595605831 0.96365975 0.921117064 1 9.056898147 -9.662113032 1.534171069 0.99928213 0.814817131 0.063077563 0.160398925 0.664001917 2.829692661 0.122273505 0.027942058 2.18E-10 9.662113032 -0.184464999 AIPTESITDS(ph)PISAQDLLSR ddPTM_HeLa_Curcumin_4h_R1 1 AIPTESITDSPISAQDLLSR 20 0 Q9UDV7-2;Q9UDV7 Q9UDV7-2 ZNF282 Zinc finger protein 282 1 0 AIPT(0.192)ES(0.009)IT(0.041)DS(0.694)PIS(0.063)AQDLLS(0.001)R 77.554 0.0067999 0 676.62 575.28 714.29 722.88 534.74 707.03 636.05 485.06 860.61 586.2 TRUE FALSE FALSE 623.064813 625.0046398 740.7622158 719.8889141 528.3635748 560.3840081 653.8958512 632.9525611 766.2032361 606.5704064 1.027192897 1.030390921 1.221230393 1.186818392 0.871067182 0.923856493 1.078021355 1.043493969 1.263172796 1 9.244531303 AIPTVNHSGT(ph)FSPQAPVPTTVPVVDVR ddPTM_HeLa_Curcumin_4h_R1 1 AIPTVNHSGTFSPQAPVPTTVPVVDVR 27 0 Q16513-3;Q16513-2;Q16513;Q16513-4;B1AL79;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 0 AIPTVNHS(0.006)GT(0.674)FS(0.319)PQAPVPTTVPVVDVR 112.48 3.31E-08 128960000 939.82 880.01 815.68 638.88 959.03 1409.1 1154.4 611.36 999.79 835.71 TRUE FALSE FALSE 865.4322553 956.0741432 845.9098183 636.2364838 947.5941936 1116.836776 1186.789357 797.7608496 890.1155384 864.7508603 1.000787967 1.105606467 0.978212173 0.735745419 1.095800232 1.291512767 1.372406102 0.922532589 1.029331775 1 9.756140734 -5.52192642 24.99970498 0.987764798 1.209922815 0.333523916 0.139710299 27.70325072 727242.4896 0.019045161 0.03847141 3.01E-06 5.52192642 0.222158017 AIPTVNHSGTFS(ph)PQAPVPTTVPVVDVR ddPTM_HeLa_Curcumin_4h_R1 1 AIPTVNHSGTFSPQAPVPTTVPVVDVR 27 0 Q16513-3;Q16513-2;Q16513;Q16513-4;B1AL79;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 0 AIPTVNHS(0.002)GT(0.116)FS(0.883)PQAPVPTTVPVVDVR 101.59 3.78E-07 73765000 1399.5 1123.2 1176.4 1281.9 1155.7 2027.1 1727.6 587.35 1440.1 1344.4 TRUE FALSE FALSE 1288.728098 1220.284403 1219.998419 1276.595837 1141.919032 1606.65661 1776.071806 766.4303112 1282.124633 1391.1178 0.926397533 0.87719703 0.876991452 0.917676301 0.820864367 1.154939294 1.276722796 0.550945658 0.921650656 1 10.44202888 -4.22680773 23.79086087 0.968266622 0.550943978 0.478361312 0.132603405 6506.596397 4469679.756 0.018242247 4.512556784 5.93E-05 4.22680773 -0.417322644 AIPVS(ph)PSAVEEDEDEDGHTVVATAR ddPTM_HeLa_Curcumin_4h_R1 5 AIPVSPSAVEEDEDEDGHTVVATAR 25 0 A0A087X0K9;G5E9E7;Q07157-2;H0Y3R8;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 0 AIPVS(0.555)PS(0.445)AVEEDEDEDGHTVVATAR;AIPVS(0.5)PS(0.5)AVEEDEDEDGHTVVATAR;AIPVS(0.5)PS(0.5)AVEEDEDEDGHTVVATAR;AIPVS(0.785)PS(0.215)AVEEDEDEDGHTVVATAR;AIPVS(0.741)PS(0.259)AVEEDEDEDGHTVVATAR ;;;; 194.11 8.32E-18 719614400 9899.8 8220.64 8353.89 8656.92 9231.28 11353.54 8681.94 21576.4 9955.5 8892.53 TRUE FALSE FALSE 9116.220384 8931.195491 8663.492512 8621.099959 9121.203015 8998.687823 8925.53187 28154.94503 8863.406557 9201.544756 0.990727169 0.970619144 0.941525879 0.936918766 0.991268668 0.977954035 0.970003636 3.059806346 0.963252018 1 13.16766037 -4.261211766 24.99994225 0.983604079 3.059806962 0.998694871 0.022645375 0.495547987 54394.86126 0.003572217 0.027789107 5.48E-05 4.261211766 2.076202883 AIPVSPS(ph)AVEEDEDEDGHTVVATAR ddPTM_HeLa_Curcumin_4h_R1 5 AIPVSPSAVEEDEDEDGHTVVATAR 25 0 A0A087X0K9;G5E9E7;Q07157-2;H0Y3R8;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 0 AIPVS(0.051)PS(0.949)AVEEDEDEDGHTVVATAR;AIPVS(0.151)PS(0.849)AVEEDEDEDGHTVVATAR;AIPVS(0.042)PS(0.958)AVEEDEDEDGHTVVATAR;AIPVS(0.413)PS(0.587)AVEEDEDEDGHTVVATAR;AIPVS(0.133)PS(0.867)AVEEDEDEDGHTVVATAR ;;;; 235.33 3.03E-36 207844600 10292.1 8821.6 8499.86 9227.79 9632.1 10913.2 8765.97 23771.1 10817.9 8493.57 TRUE FALSE FALSE 9477.469425 9584.099796 8814.872289 9189.60785 9517.243498 8649.679303 9011.919526 31018.79896 9631.203435 8788.720925 1.078367319 1.090499958 1.00297556 1.045613796 1.082892901 0.984179538 1.025396028 3.52938718 1.095859513 1 13.1014375 -4.261256244 24.99995362 1.038524091 3.529387916 0.997222685 0.039330241 0.512426245 69897.71286 0.005503223 0.042719757 5.48E-05 4.261256244 2.490863826 AIS(ph)PTSSSR ddPTM_HeLa_Curcumin_4h_R1 1 AISPTSSSR 9 0 A0A0U1RRL2;B1AM27;O14795;O14795-2 A0A0U1RRL2 UNC13B Protein unc-13 homolog B 1 0 AIS(0.56)PT(0.437)S(0.003)SSR 95.483 0.015778 109720000 2595.9 2361.8 2157.8 2364.2 1962.8 1783.2 1390 1110 2149 2075.2 TRUE FALSE FALSE 2390.431776 2565.943468 2237.769966 2354.417567 1939.394892 1413.344219 1428.999659 1448.43389 1913.260077 2147.313046 1.113219975 1.194955469 1.042125633 1.09644822 0.903172873 0.658191977 0.665482689 0.674533177 0.891001934 1 11.06831681 -5.450077193 2.693476238 1.068201366 0.662826806 0.840299055 0.075816383 0.063097469 0.893099769 0.009388235 0.022982977 3.55E-06 5.450077193 -0.40537456 AIS(ph)SANLLVR ddPTM_HeLa_Curcumin_4h_R1 1 AISSANLLVR 10 0 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 0 AIS(0.793)S(0.207)ANLLVR 134.18 0.0023281 28966000 1465.9 1610.8 1413.5 1525.8 1578.8 2903.7 2955.7 1441.4 2084.4 2086.3 TRUE FALSE FALSE 1349.872468 1750.030374 1465.885553 1519.486644 1559.973841 2301.439889 3038.628987 1880.876225 1855.746535 2158.79877 0.625288696 0.81065007 0.679028344 0.703857472 0.722611974 1.066074301 1.407555456 0.87126056 0.859619971 1 11.07601305 -5.142037306 4.795108813 0.792667481 1.15957151 0.497307795 0.157491069 0.160756581 5.623956614 0.025792955 0.068500111 7.21E-06 5.142037306 0.36690403 AIS(ph)SPTVSR ddPTM_HeLa_Curcumin_4h_R1 1 AISSPTVSR 9 0 O94811 O94811 TPPP Tubulin polymerization-promoting protein 1 0 AIS(0.5)S(0.5)PTVSR 94.409 0.016408 21721000 3808.8 3263.4 3895.5 3771.4 3904.9 4508.2 3526.5 2346.8 4081.3 3773.6 TRUE FALSE FALSE 3507.329461 3545.473755 4039.870657 3755.794946 3858.336618 3573.148502 3625.444099 3062.328517 3633.591601 3904.732319 0.898225326 0.907994061 1.034608861 0.961857213 0.988118084 0.91508155 0.928474426 0.784260806 0.930560997 1 11.93100794 -3.796626816 1.360472304 0.955904186 0.458082773 0.607008259 0.041085362 2.448413504 1.666102223 0.007139196 2.288098562 0.000159725 3.796626816 -0.497821413 AIS(ph)TPEK ddPTM_HeLa_Curcumin_4h_R1 2 AISTPEK 7 0 P42695 P42695 NCAPD3 Condensin-2 complex subunit D3 1 0 AIS(0.662)T(0.338)PEK;AIS(0.5)T(0.5)PEK ; 126.24 0.0087956 53165000 17426.4 15192.1 15702.4 15699.3 15474.7 20564 16825 4911.7 17081.2 17664.2 TRUE FALSE FALSE 16047.08205 16505.23743 16284.34476 15634.34046 15290.17431 16298.7946 17297.06422 6409.254719 15207.4351 18278.02964 0.877943759 0.903009666 0.890924519 0.855362463 0.836532964 0.891715077 0.946330899 0.350653481 0.832006261 1 14.15782294 -4.25977992 24.99396444 0.919202656 0.350653292 0.898037919 0.054126657 35.12335243 528963.5537 0.008753584 0.074864425 5.50E-05 4.25977992 -0.568549365 AIST(ph)PETPLTK ddPTM_HeLa_Curcumin_4h_R1 1 AISTPETPLTK 11 0 E9PIQ6;A0A3B3ITS5;Q14181 E9PIQ6 POLA2 DNA polymerase alpha subunit B 1 0 AIS(0.079)T(0.917)PET(0.004)PLTK 166.11 0.00076745 48280000 11379 8443.7 9406.3 9667.3 9991.6 9249.3 6040.5 3389 8177.9 8063.1 TRUE FALSE FALSE 10478.34014 9173.535804 9754.905753 9627.299274 9872.456696 7330.890919 6209.980173 4422.290499 7280.80483 8343.292125 1.255899948 1.099510321 1.169191442 1.153896943 1.183280718 0.878656867 0.744308132 0.530041431 0.87265371 1 13.02640104 -4.795977174 1.608828191 1.132196443 0.540401622 0.75027288 0.109165205 0.149272376 0.657908622 0.014846772 0.100543049 1.60E-05 4.795977174 -0.591794821 AIST(ph)PETPLTKR ddPTM_HeLa_Curcumin_4h_R1 1 AISTPETPLTKR 12 1 E9PIQ6;A0A3B3ITS5;Q14181 E9PIQ6 POLA2 DNA polymerase alpha subunit B 1 0 AIS(0.055)T(0.945)PETPLTKR 72.681 0.017611 35297000 2153.1 1928.6 1638.8 2080.4 1337.3 1621.6 1163.4 925.43 2539.3 2217.7 TRUE FALSE FALSE 1982.679863 2095.29959 1699.53537 2071.791856 1321.353571 1285.261881 1196.041873 1207.589347 2260.745143 2294.76491 0.864001299 0.913078103 0.740614153 0.902834032 0.575812174 0.560084336 0.521204533 0.526236627 0.985175054 1 11.16413065 -5.506022791 0.406602677 0.970039415 0.362045952 0.856201319 0.070829547 0.592121627 0.129649145 0.022777025 0.151644279 3.12E-06 5.506022791 -0.607993463 AISTICSLEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AISTICSLEKK 11 1 Q9UJX3-2;Q9UJX3 Q9UJX3-2 ANAPC7 Anaphase-promoting complex subunit 7 0 1 ; AISTICSLEK(1)K;AISTICSLEK(1)K 162.36 2.36E-08 2576980 924.63 740.24 735.37 823.52 840.7 993.1 809.23 619.221 1117.14 783.87 FALSE TRUE FALSE 851.4445598 804.2230472 762.6234591 820.1124924 830.6752016 787.1198655 831.9348159 808.0186324 994.5925369 811.1094242 1.049728353 0.991509929 0.940222658 1.011099696 1.024122242 0.97042377 1.025675194 0.996189427 1.226212527 1 9.663752747 -7.222181716 24.57762094 1.023482838 0.994202775 0.111299005 0.069282959 565.6463841 354128.3906 0.00491713 0.006022094 6.00E-08 7.222181716 -0.029280063 AIT(ph)PPQQPYK ddPTM_HeLa_Curcumin_4h_R1 2 AITPPQQPYK 10 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 0 AIT(1)PPQQPYK;AIT(1)PPQQPYK ; 161.67 0.0017544 91147000 15451.1 11543.2 13199.6 13509.2 13751.3 15805.5 12880.5 14270.7 14751.4 13309.5 TRUE FALSE FALSE 14228.12913 12540.94277 13688.78879 13453.30251 13587.32473 12527.26114 13241.89216 18621.77074 13133.20833 13772.00413 1.033119726 0.910611313 0.993957644 0.976858733 0.98659023 0.909617875 0.961508001 1.352146758 0.953616351 1 13.7494509 -4.258350148 24.87847912 0.993187035 1.352146899 0.873664034 0.042806217 77.2981979 622470.9822 0.006458557 0.061362763 5.52E-05 4.258350148 0.358959864 AIT(ph)PPQQPYKK ddPTM_HeLa_Curcumin_4h_R1 1 AITPPQQPYKK 11 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 0 AIT(1)PPQQPYKK 105.2 0.0027459 0 1507.6 1374.2 1693.2 1999.2 1356.8 2023.5 1788.2 1267.7 1916.4 1699.4 TRUE FALSE FALSE 1388.271869 1492.979725 1755.951481 1990.92784 1340.621046 1603.80329 1838.372079 1654.215894 1706.175715 1758.454024 0.789484314 0.849029719 0.998576851 1.132203523 0.76238618 0.912053013 1.045447907 0.94072172 0.970270301 1 10.7800919 -6.755917207 24.98965363 0.89394517 0.964829917 0.077665843 0.104883147 292.1949451 1322272.967 0.01887543 0.026264397 1.75E-07 6.755917207 0.070884747 AITGAS(ph)LADIMAK ddPTM_HeLa_Curcumin_4h_R1 2 AITGASLADIMAK 13 0 C9JXB8;C9JNW5;P83731 C9JXB8 RPL24 60S ribosomal protein L24 1 0 AITGAS(1)LADIMAK;AITGAS(1)LADIMAK ; 153.81 0.00042472 30949000 2114.22 1591.17 1630.76 1772.63 1707.44 3436.3 3084 1485.58 2102.32 1992.78 TRUE FALSE FALSE 1946.877256 1728.703645 1691.1974 1765.295327 1687.079893 2723.572645 3170.52874 1938.526503 1871.700756 2062.028957 0.944156119 0.838350809 0.820161809 0.856096284 0.818164986 1.320821726 1.537577215 0.940106344 0.90769858 1 11.00984888 -5.252851764 24.95153241 0.932841167 1.293309337 0.555003662 0.152023703 353.1369309 1026045.049 0.020811012 0.052152412 5.59E-06 5.252851764 0.36046817 AITGASLADIMAK ddPTM_HeLa_Curcumin_4h_R1 3 AITGASLADIMAK 13 0 C9JXB8;C9JNW5;P83731 C9JXB8 RPL24 60S ribosomal protein L24 0 0 ;; ;; 172.21 7.12E-06 3909130 1426.81 956.24 1032.72 1256.84 1308.59 1495.03 1313.87 1580.48 1087.33 1382.46 FALSE FALSE TRUE 1313.876483 1038.893125 1070.993512 1251.639529 1292.985919 1184.943926 1350.733656 2062.361076 968.0526194 1430.500382 0.918473353 0.726244563 0.748684534 0.874966232 0.903869677 0.828342264 0.944238585 1.441706065 0.676723076 1 10.48230417 -4.263949576 4.896611746 0.910521872 1.468643073 0.683639909 0.114451782 0.074387406 5.296874005 0.014874151 0.140241568 5.45E-05 4.263949576 0.558121201 AITVFS(ph)PDGHLFQVEYAQEAVK ddPTM_HeLa_Curcumin_4h_R1 1 AITVFSPDGHLFQVEYAQEAVK 22 0 O14818;Q8TAA3-2;Q8TAA3-5;Q8TAA3;F5GY34;O14818-4 O14818 PSMA7;PSMA8 Proteasome subunit alpha type-7;Proteasome subunit alpha type-7-like 1 0 AIT(0.015)VFS(0.985)PDGHLFQVEYAQEAVK 93.776 0.00011736 16237000 1502.8 1141 1062.7 1027.2 1070.3 2094.4 1597 924.89 1400.9 992.43 TRUE FALSE FALSE 1383.851794 1239.622956 1102.084597 1022.949719 1057.537372 1659.997831 1641.807522 1206.884703 1247.224775 1026.916869 1.347579182 1.207130775 1.073197481 0.996136834 1.029817898 1.616487061 1.598773544 1.175250636 1.214533341 1 10.00410368 -13.5228128 0.049650724 2.26E-30 1.815615057 0.116816425 0.20482725 604.2952749 2.377747048 85.95723906 21.41917839 3.00E-14 13.5228128 1.815615057 AITVFS(ph)PDGHLFQVEYAQEAVKK ddPTM_HeLa_Curcumin_4h_R1 2 AITVFSPDGHLFQVEYAQEAVKK 23 1 O14818;Q8TAA3-2;Q8TAA3-5;Q8TAA3;F5GY34;O14818-4 O14818 PSMA7;PSMA8 Proteasome subunit alpha type-7;Proteasome subunit alpha type-7-like 1 0 AIT(0.031)VFS(0.969)PDGHLFQVEYAQEAVKK;AIT(0.026)VFS(0.974)PDGHLFQVEYAQEAVKK ; 102.27 1.70E-05 44819000 1604.21 1540.95 1963.33 1812.4 1382.14 2780.7 2380.29 1043.83 2030.54 1598.56 TRUE FALSE FALSE 1477.235086 1674.142852 2036.092737 1804.900769 1365.658883 2203.951475 2447.074531 1362.088962 1807.794842 1654.109841 0.893069522 1.012111052 1.230929583 1.091161375 0.825615597 1.332409384 1.479390589 0.823457384 1.092911001 1 10.69183932 -6.950124034 6.374574613 0.949583258 1.139360305 0.081751108 0.197022025 0.257809749 23.88369848 0.030518918 0.040107681 1.12E-07 6.950124034 0.189777047 AIVAIENPADVSVISSR ddPTM_HeLa_Curcumin_4h_R1 1 AIVAIENPADVSVISSR 17 0 C9J9K3;A0A0C4DG17;P08865;F8WD59 C9J9K3 RPSA 40S ribosomal protein SA 0 0 206.2 1.80E-18 1373300 310.24 325.15 304.26 293.27 363.79 286.01 312.76 281.09 302.63 231.85 FALSE FALSE TRUE 285.6841766 353.2545172 315.5361433 292.0565264 359.4520418 226.688302 321.5352038 366.793047 269.4322461 239.9067702 1.190813316 1.472465812 1.315244847 1.217375092 1.498298866 0.944901646 1.340250646 1.528898274 1.123070624 1 7.906330061 -8.119054068 0.922183083 1.031048104 1.316646887 0.276609971 0.164893812 0.388668352 0.703747144 0.048975341 0.035185742 7.60E-09 8.119054068 0.285598783 AK(ac)LVPSQEETK ddPTM_HeLa_Curcumin_4h_R1 2 AKLVPSQEETK 11 1 P49321-4;P49321;P49321-3 P49321-4 NASP Nuclear autoantigenic sperm protein 0 1 ; AK(1)LVPSQEETK;AK(1)LVPSQEETK 135.99 0.00038801 7703900 9831 9299 10043.5 9389 11194.5 11687.2 10930.9 9808.8 8869.6 7882.8 FALSE TRUE FALSE 9052.865976 10102.76412 10415.72095 9350.150806 11061.0129 9263.142978 11237.59163 12799.45797 7896.627071 8156.726713 1.109865059 1.238580681 1.276948623 1.146311644 1.356060254 1.135644641 1.377708489 1.569190487 0.968112252 1 12.9937746 -1 0.154802595 0.94774055 2.923973043 0.731285046 0.090587534 24.67273764 0.244368116 0.174581128 11.07936251 0.1 1 1.976232493 AK(ac)MQASIEK ddPTM_HeLa_Curcumin_4h_R1 1 AKMQASIEK 9 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 0 1 AK(1)MQASIEK 116.52 0.0015895 3262000 681.71 573 730.28 525 611.7 941.95 739.51 834.25 753.9 646.35 FALSE TRUE FALSE 627.7519342 622.5275668 757.3448192 522.8276891 604.405877 746.578952 760.2586603 1088.608985 671.1990562 668.8106144 0.938609407 0.930797977 1.132375598 0.781727559 0.903702579 1.116278564 1.136732348 1.627678989 1.003571178 1 9.385453934 -3.922414528 1.240939605 0.963746436 2.454184929 0.824740924 0.091389015 0.834383188 0.617035321 0.012832403 1.94354445 0.00011956 3.922414528 1.490438493 AKADS(ph)PVNGLPK ddPTM_HeLa_Curcumin_4h_R1 1 AKADSPVNGLPK 12 1 Q96S94;Q96S94-3;A0A0A0MSF3 Q96S94 CCNL2 Cyclin-L2 1 0 AKADS(1)PVNGLPK 141.34 0.010731 61395000 4242.2 3358.8 3797.6 3727.6 3384.5 3911.2 3351.1 2898.7 4027.3 3872.1 TRUE FALSE FALSE 3906.425394 3649.119705 3938.342397 3712.176179 3344.142048 3099.973032 3445.122847 3782.500286 3585.515266 4006.655187 0.974984173 0.910764599 0.98295017 0.926502533 0.834646829 0.773705968 0.859850096 0.944054357 0.894889902 1 11.96818264 -5.966578701 3.095360642 0.98030553 0.848107702 0.395844816 0.052759817 0.123453569 2.434676406 0.007148347 0.013335753 1.08E-06 5.966578701 -0.132197828 AKAGLES(ph)GAEPGDGDSDTTK ddPTM_HeLa_Curcumin_4h_R1 1 AKAGLESGAEPGDGDSDTTK 20 1 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 0 AKAGLES(0.979)GAEPGDGDS(0.014)DT(0.005)T(0.002)K 61.757 0.0063214 57237000 2191.8 1871.1 1651.4 2326 1933.8 2396.6 1784.3 2010.3 2639.7 2277.3 TRUE FALSE FALSE 2018.316717 2032.829547 1712.602337 2316.375628 1910.740698 1899.518145 1834.362656 2623.231216 2350.131514 2356.436005 0.856512425 0.86267123 0.72677651 0.98299959 0.810860424 0.806097912 0.778447898 1.113219799 0.997324565 1 11.20239079 -9.086090581 0.817127193 1.001839048 0.859427657 0.196726777 0.104608516 0.788090098 0.938318656 0.068774634 0.01949926 8.20E-10 9.086090581 -0.142411391 AKAGLESGAEPGDGDSDT(ph)TKK ddPTM_HeLa_Curcumin_4h_R1 1 AKAGLESGAEPGDGDSDTTKK 21 2 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 0 AKAGLESGAEPGDGDS(0.248)DT(0.376)T(0.376)KK 73.688 0.0010279 30269000 4408.4 3843.7 3695.5 4461.3 3336.4 5357.7 3713.3 3782.9 6089 4749.1 TRUE FALSE FALSE 4059.470488 4175.932301 3832.458481 4442.840323 3296.615609 4246.452626 3817.485204 4936.288796 5421.051934 4914.130872 0.82608107 0.849780441 0.779885311 0.904094832 0.670844081 0.86413096 0.776838327 1.004509022 1.103155792 1 12.26272056 -9.143781713 0.697597244 1.012135485 0.827173529 0.457960624 0.089785017 0.658941199 0.525405864 0.07113383 0.016211636 7.18E-10 9.143781713 -0.184961955 AKAGLESGAEPGDGDSDTT(ph)KK ddPTM_HeLa_Curcumin_4h_R1 1 AKAGLESGAEPGDGDSDTTKK 21 2 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 0 AKAGLESGAEPGDGDS(0.218)DT(0.218)T(0.563)KK 63.109 0.016739 10108000 1308.5 1060.1 933.25 1263.7 968.22 1534.6 1042.6 995.09 1658.7 1075.3 TRUE FALSE FALSE 1204.930844 1151.73032 967.837066 1258.471144 956.6746089 1216.306661 1071.85255 1298.48836 1476.74476 1112.666595 1.082921739 1.035108204 0.869835646 1.131040646 0.859803479 1.093145662 0.963318711 1.167005791 1.327212272 1 10.11980565 -4.245683265 23.85726565 1.022304701 1.167005996 0.064605933 0.129336476 1868.236799 2828721.8 0.010951851 0.343564325 5.68E-05 4.245683265 0.144701295 AKDDATLSGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 AKDDATLSGKR 11 2 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 0 1 ; AKDDATLSGK(1)R;AKDDATLSGK(1)R 138.63 4.04E-05 205759000 16439.3 15215.6 15625.8 13509.9 12925.1 20888 11633.5 14773.6 17486 15850.9 FALSE TRUE FALSE 15138.11206 16530.76866 16204.90589 13453.99961 12770.97662 16555.59334 11959.9047 19278.00263 15567.82955 16401.7176 0.922958951 1.007868144 0.988000543 0.820279921 0.778636539 1.009381685 0.729186113 1.175364868 0.949158493 1 14.00155928 -6.290727448 24.6882514 0.968380351 0.891986188 0.076447992 0.1199815 1089.436353 918333.3399 0.01677084 0.025620341 5.12E-07 6.290727448 -0.076394163 AKDPDAELACS(ph)MQYDDQELEQLSR ddPTM_HeLa_Curcumin_4h_R1 1 AKDPDAELACSMQYDDQELEQLSR 24 1 Q9HCC9-5;Q9HCC9-4;Q9HCC9-3;Q9HCC9-2;Q9HCC9 Q9HCC9-5 ZFYVE28 Lateral signaling target protein 2 homolog 1 0 AKDPDAELACS(0.991)MQY(0.009)DDQELEQLSR 80.868 0.00030096 0 1018.9 891.11 993.26 1131 855.48 1125.4 1117.3 697.73 1016.9 1111.1 TRUE FALSE FALSE 938.2529899 968.1335777 1030.071089 1126.320222 845.2789597 891.9793541 1148.648431 910.464665 905.3486142 1149.710642 0.816077503 0.842067162 0.895939423 0.979655385 0.735210173 0.775829432 0.999076105 0.791907661 0.787457801 1 10.1670551 -9.376346631 1.017379265 1.00290629 0.85477826 0 0.10337821 0.540933093 0.970280586 0.059590656 0.01420686 4.20E-10 9.376346631 -0.14812803 AKEAAEQDVEK ddPTM_HeLa_Curcumin_4h_R1 2 AKEAAEQDVEK 11 1 P26373;P26373-2;J3KS98 P26373 RPL13 60S ribosomal protein L13 0 0 ; ; 166.7 5.10E-09 11542400 13774.7 11598.2 11768.4 12010.3 11676.6 14541 10357.7 11035.9 13407.9 13203.6 FALSE FALSE TRUE 12684.41796 12600.69673 12204.54726 11960.60456 11537.36417 11525.03269 10648.30919 14400.69511 11937.08691 13662.42412 0.928416352 0.922288506 0.893292958 0.87543795 0.844459524 0.843556941 0.77938652 1.054036603 0.873716612 1 13.73792586 -7.811854263 0.54323595 0.994360757 0.869549719 0 0.076289348 0.616733356 0.433730874 0.029071385 0.021602563 1.54E-08 7.811854263 -0.124811038 AKEAQDDLVK ddPTM_HeLa_Curcumin_4h_R1 1 AKEAQDDLVK 10 1 E7EQR4;P15311 E7EQR4 EZR Ezrin 0 0 93.561 0.0083144 6469100 4446 3030.1 3192.1 3780.8 4273.8 5597.4 3698.9 4107.6 5432 4313.4 FALSE FALSE TRUE 4094.094409 3292.008342 3310.402034 3765.156051 4222.837726 4436.436144 3802.681179 5359.988331 4836.12319 4463.290329 0.91728167 0.737574323 0.741695429 0.843583046 0.946126605 0.993983321 0.851990549 1.200905148 1.083533186 1 12.12389194 -4.252773686 24.12615714 0.91864821 1.200905386 0.405292259 0.106965205 573.9551769 1597889.574 0.015085729 0.231147751 5.59E-05 4.252773686 0.282257176 AKESDFSDT(ph)LSPS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 AKESDFSDTLSPSK 14 1 A0A590UJP6;H7C5G9;H7BZW9;H7BZK0;A0A590UJS6;A0A590UJU9;H7C3M8;A0A5F9VB99;A0A590UJK3;Q14BN4-4;Q14BN4-6;Q14BN4-2;Q14BN4-3;Q14BN4 A0A590UJP6 SLMAP Sarcolemmal membrane-associated protein 2 0 AKES(0.038)DFS(0.126)DT(0.836)LS(0.001)PS(0.999)K 115.82 0.0090588 56058000 1510.5 1262.2 1247 1262.1 1275.6 1724.3 1193.1 1459 1401.5 1247.6 TRUE FALSE FALSE 1390.942331 1371.298944 1293.214917 1256.877765 1260.389303 1366.660743 1226.575175 1903.842384 1247.758956 1290.954007 1.077453049 1.06223687 1.001751348 0.973603829 0.97632394 1.058644023 0.950130809 1.474756167 0.966540209 1 10.33422189 -4.255545786 24.99240503 1.025579788 1.474756363 0.903592862 0.045448667 148.2177017 628514.6331 0.006422343 0.077876075 5.55E-05 4.255545786 0.449176575 AKFEELNMDLFR ddPTM_HeLa_Curcumin_4h_R1 2 AKFEELNMDLFR 12 1 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 0 ; ; 103.46 0.0064879 47710000 6248.3 4429.2 5144.6 4746.4 4724.7 8548.6 5837.5 4212.2 4688.4 5456 FALSE FALSE TRUE 5753.740462 4812.040312 5335.263402 4726.760654 4668.361038 6775.523997 6001.284539 5496.480389 4174.09425 5645.595594 1.019155617 0.852352995 0.945031098 0.837247475 0.826903196 1.200143348 1.063002909 0.973587339 0.7393541 1 12.46291007 -1.201983561 14.27774271 0.986941821 1.121669843 0 0.134839856 0 0 0.014750666 0 0.062808213 1.201983561 0.134728021 AKGSET(ph)PGATPGSK ddPTM_HeLa_Curcumin_4h_R1 1 AKGSETPGATPGSK 14 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 AKGS(0.015)ET(0.985)PGATPGSK 144.08 0.0063699 8946000 2308.6 2129.1 2198.4 2086.9 1753.9 3093.9 1735.4 1135.6 2956.3 2647.7 TRUE FALSE FALSE 2125.871874 2313.129917 2279.874638 2078.264961 1732.985888 2452.190265 1784.090653 1481.839212 2632.001286 2739.707378 0.775948516 0.844298167 0.832159907 0.758571874 0.632544155 0.895055539 0.651197521 0.540874994 0.960687009 1 11.4198061 -13.52287875 0.041622231 2.285356712 1.65E-12 0.648612903 0.083051694 290.6227986 0.964512789 47.06919237 14.62355596 3.00E-14 13.52287875 -2.285356712 AKGSETPGATPGS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 AKGSETPGATPGSK 14 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 AKGSET(0.003)PGAT(0.203)PGS(0.794)K 91.202 0.0040027 84862000 9413.7 8057 7601.6 7602.5 7079.4 10183 6958.7 4428.3 10030 9508.5 TRUE FALSE FALSE 8668.595712 8753.411179 7883.321983 7571.042869 6994.982779 8070.931014 7153.942394 5778.468285 8929.734094 9838.919667 0.881051579 0.889671984 0.801238576 0.769499409 0.710950289 0.820306628 0.727106495 0.587307192 0.907592947 1 13.2642842 -2.618879992 0.119977669 1.105980749 1.00E-15 0.782578093 0.05215627 15.1876898 0.186321127 0.23338609 2.733705206 0.002405027 2.618879992 -1.105980749 ESS(ph)PFLSPLEASR ddPTM_HeLa_Curcumin_4h_R1 1 ESSPFLSPLEASR 13 0 Q9UP95-3;Q9UP95-5;Q9UP95-2;Q9UP95-6;Q9UP95;Q9UP95-4 Q9UP95-3 SLC12A4 Solute carrier family 12 member 4 1 0 ES(0.211)S(0.787)PFLSPLEAS(0.001)R 114.87 0.0030065 2932500 1725.5 1220.1 1446.8 1501.2 1323.8 813.59 354.09 363.88 1906.7 1676.3 TRUE FALSE FALSE 1588.924854 1325.560007 1500.419681 1494.988432 1308.01455 644.842263 364.0248124 474.8253369 1697.53978 1734.5513 0.916043737 0.764209169 0.865018913 0.861887701 0.754093897 0.371763154 0.209866847 0.273745341 0.978662194 1 10.76034679 -5.305310117 1.557111899 0.933946922 0.216277922 0.942407731 0.068067323 0.071756338 0.326990509 0.01209127 0.042382334 4.95E-06 5.305310117 -0.717669 down AKNWEDEDFYDS(ph)DDDTFLDR ddPTM_HeLa_Curcumin_4h_R1 2 AKNWEDEDFYDSDDDTFLDR 20 1 A0A087X0M4;Q9BWU0;A0A087WWF4 A0A087X0M4 SLC4A1AP Kanadaptin 1 0 AKNWEDEDFYDS(0.975)DDDT(0.024)FLDR;AKNWEDEDFY(0.002)DS(0.915)DDDT(0.082)FLDR ; 125.91 3.41E-05 128254000 9431.3 8229 8538.7 8829.3 8516.9 11015.5 8446.9 8070.1 10586.4 9052.1 TRUE FALSE FALSE 8684.802653 8940.278092 8855.151733 8792.766696 8415.34153 8730.76113 8683.89728 10530.63634 9425.098406 9366.659801 0.92720381 0.954478788 0.945390558 0.938730229 0.898435697 0.932110412 0.927107151 1.124268049 1.006239002 1 13.19331895 -4.256253556 24.89709027 0.952459545 1.124268125 0.735603135 0.031635626 237.2357695 1138929.308 0.005004491 0.055651346 5.54E-05 4.256253556 0.17180858 AKPAEAPAAAAPK ddPTM_HeLa_Curcumin_4h_R1 1 AKPAEAPAAAAPK 13 1 Q86SW4;P36957-2;P36957 Q86SW4 DLST "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial" 0 0 98.368 0.002122 0 2515.5 2249 1932.5 2498.9 2957.1 4371.6 3154.7 2664.2 3547.8 2347.7 FALSE FALSE TRUE 2316.395521 2443.393539 2004.12015 2488.560214 2921.838514 3464.880882 3243.212392 3476.502316 3158.615216 2429.2824 0.953530771 1.005808768 0.824984427 1.024401368 1.202757865 1.426298104 1.335049557 1.431082 1.30022562 1 11.2463145 -5.59134011 2.411643273 0.968303478 1.391308403 0.66113827 0.119048802 0.054489839 0.637797474 0.008267419 0.019147856 2.56E-06 5.59134011 0.423004925 AKPAMPQDSVPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 AKPAMPQDSVPSPR 14 1 P53396 P53396 ACLY ATP-citrate synthase 1 0 AKPAMPQDSVPS(1)PR;AKPAMPQDSVPS(1)PR;AKPAMPQDSVPS(1)PR;AKPAMPQDSVPS(1)PR ;;; 107.69 0.0020848 454514000 14536.6 12167.3 12133.6 13049.9 13710.9 18520.9 18734.1 14073.5 15152.9 13705.2 TRUE FALSE FALSE 13386.01277 13218.9872 12583.28189 12995.90297 13547.40647 14679.45657 19259.72843 18364.44536 13490.66478 14181.45468 0.94390971 0.932131963 0.88730544 0.916401262 0.955290327 1.035116418 1.358092584 1.294962032 0.951289207 1 13.79171791 -4.845232802 4.056709334 0.958813187 1.329003187 0.946174899 0.035997304 0.038907839 1.196287641 0.00617714 0.021009873 1.43E-05 4.845232802 0.37019 MDETDASS(ph)AVK ddPTM_HeLa_Curcumin_4h_R1 1 MDETDASSAVK 11 0 K7EJM5;A0A087WX29;A0A0A0N0M3;K7EN94;B1AKP7;G3V162;A0A087X260;A0A087WYY0;Q13148 K7EJM5 TARDBP;TDP43 TAR DNA-binding protein 43 1 0 MDETDAS(0.031)S(0.969)AVK 155.86 0.00042707 6904500 1528.8 1301.5 1467.1 1485.5 1519.9 2734.1 2550.5 2510 1472.8 1546.2 TRUE FALSE FALSE 1407.793867 1413.995861 1521.472017 1479.353395 1501.776185 2167.01684 2622.060166 3275.287445 1311.237525 1599.930335 0.879909479 0.883785894 0.950961416 0.924636131 0.938650985 1.354444499 1.638858961 2.047143787 0.819559137 1 10.64379337 -4.693696051 1.284198144 0.931697064 2.144504085 0.972550662 0.064078068 0.078309502 0.179664706 0.009472378 0.10128992 2.02E-05 4.693696051 1.212807021 up AKPTGSGKEEGPAPCK(ac)QMK ddPTM_HeLa_Curcumin_4h_R1 3 AKPTGSGKEEGPAPCKQMK 19 3 D6RCB6;Q8IUF8-2;Q8IUF8-4;Q8IUF8 D6RCB6 MINA Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA 0 1 ;; AKPTGSGKEEGPAPCK(1)QMK;AKPTGSGKEEGPAPCK(1)QMK;AKPTGSGKEEGPAPCK(1)QMK 87.429 0.0027357 72711000 14236.1 12522.2 12901.3 13604.5 11375.9 17377.7 13367.5 14387.7 13868.3 11837.5 FALSE TRUE FALSE 13109.29766 13604.56317 13379.43353 13548.20818 11240.24982 13773.36913 13742.55607 18774.4435 12346.98219 12248.85224 1.070247024 1.11068065 1.092300998 1.106079812 0.917657393 1.12446202 1.121946432 1.532751243 1.008011358 1 13.58035895 -4.055033775 1.738556607 1.044374865 1.928564952 0.848729456 0.060310293 0.46205021 0.881957858 0.00868424 0.797079528 8.81E-05 4.055033775 0.884190087 AKS(ph)PQPPVEEEDEHFDDTVVCLDTYNCDLHFK ddPTM_HeLa_Curcumin_4h_R1 2 AKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 0 AKS(0.792)PQPPVEEEDEHFDDT(0.208)VVCLDTYNCDLHFK;AKS(0.872)PQPPVEEEDEHFDDT(0.105)VVCLDT(0.016)Y(0.006)NCDLHFK ; 60.541 0.00025515 143871000 2668.76 2739.52 2509.42 2660.64 2596.49 3068.7 2126.54 1940.82 3249.1 2550.52 TRUE FALSE FALSE 2457.52483 2976.311902 2602.421313 2649.630977 2565.528553 2432.217029 2186.204989 2532.567084 2892.681859 2639.15038 0.931180295 1.127753812 0.986082996 1.003971201 0.972103966 0.921590921 0.828374543 0.959614542 1.096065567 1 11.36585784 -5.188214391 3.392319512 0.983904475 0.890868949 0.303454244 0.067548298 0.233254614 5.229426326 0.008583238 0.023733461 6.48E-06 5.188214391 -0.093035527 AKS(ph)PTPDGS(ph)ER ddPTM_HeLa_Curcumin_4h_R1 1 AKSPTPDGSER 11 1 J3QR07;Q96MU7-2;Q96MU7 J3QR07 YTHDC1 YTH domain-containing protein 1 2 0 AKS(0.861)PT(0.139)PDGS(1)ER 108.66 0.0032811 0 3701.1 6715.8 3882.4 3377.7 3020.7 2315.3 2001.3 1807.9 2614.9 3944.7 TRUE FALSE FALSE 3408.15403 7296.283827 4026.285159 3363.723972 2984.680125 1835.080681 2057.451092 2359.120387 2328.052012 4081.778031 0.834967998 1.78752587 0.986404731 0.824083021 0.731220586 0.449578754 0.504057564 0.577963909 0.570352428 1 11.99498201 -5.705274477 1.959078859 0.999278211 0.514049383 0.371486781 0.292561274 0.268049742 2.088336361 0.042047381 0.096849863 1.97E-06 5.705274477 -0.485228829 AVS(ph)PSNPK ddPTM_HeLa_Curcumin_4h_R1 1 AVSPSNPK 8 0 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-3 MAP7 Ensconsin 1 0 AVS(0.954)PS(0.046)NPK 99.013 0.01563 92984000 8089.2 8604.9 7343.5 6533.3 6052 4077.9 2601 1805.9 8082.4 5820.9 TRUE FALSE FALSE 7448.931284 9348.669213 7615.65657 6506.266936 5979.833853 3232.097573 2673.97706 2356.510597 7195.780941 6023.175842 1.236711575 1.552116269 1.264392203 1.080205378 0.99280413 0.536610197 0.443948032 0.391240545 1.194682196 1 12.55630866 -5.295322012 1.937009002 1.163128176 0.406814081 0.852550506 0.141620694 0.12204932 0.876000819 0.0260094 0.080607006 5.07E-06 5.295322012 -0.756314095 down ASVALTPT(ph)APSR ddPTM_HeLa_Curcumin_4h_R1 1 ASVALTPTAPSR 12 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 0 AS(0.007)VALT(0.209)PT(0.779)APS(0.006)R 120.59 0.010162 38618000 6447.3 4593.3 4604.2 4477.6 3872.6 2936.1 1675.7 930.62 5481.7 4369.3 TRUE FALSE FALSE 5936.989402 4990.324385 4774.835702 4459.072878 3826.421774 2327.119763 1722.715632 1214.361754 4880.371225 4521.13285 1.313164112 1.103777427 1.056114886 0.986273358 0.846341371 0.514720501 0.381036278 0.268596786 1.079457602 1 12.1424686 -5.29229374 1.002195091 1.145826928 0.237820277 0.944466237 0.077633053 0.150808865 0.254426561 0.019144157 0.099094635 5.10E-06 5.29229374 -0.908006651 down AKSPQPPVEEEDEHFDDT(ph)VVCLDTYNCDLHFK ddPTM_HeLa_Curcumin_4h_R1 2 AKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 0 AKS(0.192)PQPPVEEEDEHFDDT(0.796)VVCLDT(0.009)Y(0.003)NCDLHFK;AKS(0.363)PQPPVEEEDEHFDDT(0.637)VVCLDTYNCDLHFK ; 70.67 1.12E-05 44851000 4501.4 4575.9 4063.6 4318.2 3960.8 5246.6 3847.3 2827.2 5079.4 4233.8 TRUE FALSE FALSE 4145.10944 4971.420406 4214.200591 4300.332433 3913.570047 4158.396019 3955.244884 3689.200265 4522.202528 4380.924235 0.946172364 1.134788036 0.961943272 0.981603927 0.893320641 0.94920519 0.902833437 0.842105471 1.032248513 1 12.09701955 -5.778175798 8.4023427 0.986782436 0.90098214 0.457857602 0.056827472 0.150391884 58.46854139 0.008343749 0.015494855 1.67E-06 5.778175798 -0.085800296 SGSIVELIAGGGSSCS(ph)PVLSR ddPTM_HeLa_Curcumin_4h_R1 1 SGSIVELIAGGGSSCSPVLSR 21 0 P42858 P42858 HTT Huntingtin 1 0 SGSIVELIAGGGS(0.002)S(0.035)CS(0.962)PVLSR 171.39 1.17E-08 117560000 1862.7 1304.7 1642.7 1534.9 1455.9 1138.1 817.38 534.31 1536.8 1626.6 TRUE FALSE FALSE 1715.265329 1417.472454 1703.579907 1528.54899 1438.539343 902.045231 840.3134829 697.2186593 1368.216885 1683.124229 1.019096095 0.842167459 1.012153398 0.908161717 0.854683997 0.535935028 0.499258147 0.41424076 0.812903089 1 10.71692595 -5.291796301 1.296884773 0.995414093 0.418382764 0.859110651 0.080294166 0.07625444 0.233216312 0.008493807 0.034767284 5.11E-06 5.291796301 -0.577031329 down DDSFDSLDS(ph)FGSR ddPTM_HeLa_Curcumin_4h_R1 2 DDSFDSLDSFGSR 13 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 DDSFDS(0.031)LDS(0.969)FGSR;DDSFDS(0.036)LDS(0.964)FGSR ; 247.11 1.12E-40 18386000 2317.49 2095.39 2092.18 2107.11 2689.67 3270.4 4380.4 4066 2092.83 2141.72 TRUE FALSE FALSE 2134.058221 2276.506175 2169.718031 2098.391337 2657.597442 2592.082175 4503.302235 5305.704682 1863.251785 2216.144611 0.962959823 1.027237196 0.979050745 0.946865709 1.199198567 1.169635845 2.032043493 2.394114832 0.840762726 1 11.11383631 -4.674565826 1.790768566 0.991418091 2.479161703 0.968840176 0.087492255 0.040163707 0.214438244 0.009929659 0.076893604 2.12E-05 4.674565826 1.487743612 up AKT(ph)SPVKSNTPAAHLEIKPDELAK ddPTM_HeLa_Curcumin_4h_R1 1 AKTSPVKSNTPAAHLEIKPDELAK 24 3 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3 B8ZZZ7 SPATS2L SPATS2-like protein 1 0 AKT(0.408)S(0.408)PVKS(0.092)NT(0.092)PAAHLEIKPDELAK 51.31 0.0057929 60331000 2948.3 2494.6 1806.4 2729.6 1797.3 3377.5 2012.4 2150.6 3531.8 2561.1 TRUE FALSE FALSE 2714.938944 2710.222108 1873.346773 2718.305638 1775.868371 2676.968428 2068.862528 2806.30804 3144.370376 2650.098034 1.024467363 1.02268749 0.70689716 1.025737766 0.670114218 1.010139396 0.78067396 1.058944991 1.186510965 1 11.37183001 AKTQT(ph)PPVS(ph)PAPQPTEERLPSSPVYEDAASFK ddPTM_HeLa_Curcumin_4h_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 2 0 AKT(0.093)QT(0.897)PPVS(0.929)PAPQPT(0.074)EERLPS(0.003)S(0.003)PVY(0.001)EDAASFK 61.03 0.00028567 58743000 5633 4591.4 4099.2 4702 2845.4 3928.3 3947.7 4544.6 6900.3 5990.3 TRUE FALSE FALSE 5187.142106 4988.260157 4251.119958 4682.54437 2811.470463 3113.526299 4058.461837 5930.227619 6143.354354 6198.462479 0.83684335 0.804757659 0.685834588 0.755436431 0.453575459 0.502306227 0.654752989 0.956725581 0.991109388 1 12.59769469 -7.429543037 0.669393947 0.968165068 0.641165384 0.480169414 0.131835277 0.397898078 0.388525877 0.040987257 0.043256293 3.72E-08 7.429543037 -0.326999683 AKTQT(ph)PPVSPAPQPTEER ddPTM_HeLa_Curcumin_4h_R1 2 AKTQTPPVSPAPQPTEER 18 1 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 1 0 AKT(0.151)QT(0.542)PPVS(0.306)PAPQPTEER;AKT(0.362)QT(0.622)PPVS(0.015)PAPQPTEER ; 114.21 0.004446 214565000 6040.5 5378.2 5418.8 5247 5561.1 5815.6 5767.2 3003.1 6358.6 4723.2 TRUE FALSE FALSE 5562.388051 5843.067643 5619.625495 5225.289304 5494.787515 4609.379005 5929.01211 3918.731365 5661.077488 4887.330848 1.138123901 1.195553938 1.149835292 1.069149903 1.124292111 0.943128089 1.213139093 0.801814219 1.158316812 1 12.25483106 -4.243874334 24.37096755 1.084224745 0.801813891 0.529884941 0.083992455 1741.067234 2415625.403 0.011874882 0.472228666 5.70E-05 4.243874334 -0.282410855 AKTQT(ph)PPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_HeLa_Curcumin_4h_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 2 0 AKT(0.171)QT(0.708)PPVS(0.122)PAPQPT(0.073)EERLPS(0.454)S(0.454)PVY(0.019)EDAASFK 63.085 0.00018103 84913000 2843.5 1863.2 1887 2216.7 1615 2804.9 3035.9 3474.3 2736.7 2466.2 TRUE FALSE FALSE 2618.433975 2024.246706 1956.93388 2207.527883 1595.74218 2223.132122 3121.079183 4533.598076 2436.490857 2551.900266 1.026072221 0.79323112 0.76685359 0.86505257 0.62531526 0.871167322 1.223041208 1.776557703 0.95477511 1 11.31735623 -4.362073445 2.585966081 0.934432359 1.859429547 0.816312901 0.130480957 0.153118509 1.492689789 0.022322141 0.275260768 4.34E-05 4.362073445 0.924997188 VGDST(ph)PVSEKPVSAAVDANASES(ph)P ddPTM_HeLa_Curcumin_4h_R1 1 VGDSTPVSEKPVSAAVDANASESP 24 1 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 2 0 VGDS(0.169)T(0.698)PVS(0.126)EKPVS(0.007)AAVDANAS(0.042)ES(0.958)P 64.209 0.0044056 7882800 2484.5 2199.4 2016.4 2264.9 2380.1 3916.7 3830.9 3806.3 2566.9 2227.4 TRUE FALSE FALSE 2287.849203 2389.506336 2091.129558 2255.528444 2351.718862 3104.33227 3938.384744 4966.823348 2285.317492 2304.801984 0.992644583 1.036751249 0.907292502 0.978621356 1.020356143 1.346897604 1.708773583 2.154989184 0.991546132 1 11.17042709 -4.607363155 1.272299371 0.988153865 2.319217222 0.989025025 0.04071694 0.056191802 0.116254633 0.006226087 0.082452325 2.47E-05 4.607363155 1.331063357 up AKTQTPPVSPAPQPT(ph)EERLPSSPVYEDAASFK ddPTM_HeLa_Curcumin_4h_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 1 0 AKTQTPPVS(0.001)PAPQPT(0.448)EERLPS(0.195)S(0.195)PVY(0.044)EDAAS(0.117)FK 68.93 2.42E-05 133840000 2736.7 2156.5 1994 3629.2 1585.2 3367.7 2965.7 2731.4 3782.1 2854.9 TRUE FALSE FALSE 2520.087307 2342.898251 2067.899394 3614.183332 1566.297525 2669.201058 3048.90956 3564.191286 3367.213092 2954.107563 0.853079062 0.793098491 0.700008158 1.223443377 0.530210052 0.903555812 1.032091586 1.206520484 1.139841059 1 11.52850664 -4.470374067 2.699229067 0.89424143 1.209091752 0.21065138 0.190416222 0.350032937 4.305030448 0.023494015 0.195962005 3.39E-05 4.470374067 0.314850322 AKTQTPPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_HeLa_Curcumin_4h_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 1 0 AKTQTPPVSPAPQPT(0.133)EERLPS(0.388)S(0.388)PVY(0.085)EDAAS(0.006)FK 72.292 1.06E-05 123500000 3278.1 2068.5 1986 2699.8 1546.5 3767.7 2973.2 2976.3 3926.7 2849.5 TRUE FALSE FALSE 3018.634926 2247.291923 2059.602907 2688.628943 1528.058998 2986.236549 3056.61999 3883.760169 3495.950834 2948.519913 1.023779732 0.762176275 0.698520942 0.911857143 0.518246118 1.012791718 1.036662488 1.317189737 1.185662955 1 11.52577522 -4.300649657 2.141674615 0.929640356 1.399235631 0.322280232 0.183350706 0.61398176 3.330855743 0.026145915 0.53309099 5.00E-05 4.300649657 0.469595275 AKVPAQANGTPT(ph)TK ddPTM_HeLa_Curcumin_4h_R1 2 AKVPAQANGTPTTK 14 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 0 AKVPAQANGT(0.346)PT(0.521)T(0.134)K;AKVPAQANGT(0.242)PT(0.641)T(0.118)K ; 101.67 0.0037462 49369000 5092.2 5070.2 5028.7 6114.8 5108.7 6620.4 4192.6 3250.1 6788.3 5111 TRUE FALSE FALSE 4689.146997 5508.445496 5215.068046 6089.498578 5047.782089 5247.254413 4310.233072 4241.040528 6043.640473 5288.60687 0.886650703 1.041568343 0.986094859 1.15143718 0.954463475 0.992180841 0.815003493 0.801920172 1.142766067 1 12.36867202 -4.755558008 23.608187 0.972687693 0.808461627 0.418229402 0.086457128 50.68836141 203452.4367 0.010830465 0.038327227 1.76E-05 4.755558008 -0.164226066 ALAAAGYDVEK ddPTM_HeLa_Curcumin_4h_R1 2 ALAAAGYDVEK 11 0 P10412;P22492;Q02539;P16403;P16402 P10412;P16403;P16402 HIST1H1E;HIST1H1T;HIST1H1A;HIST1H1C;HIST1H1D Histone H1.4;Histone H1t;Histone H1.1;Histone H1.2;Histone H1.3 0 0 ; ; 142.36 2.40E-05 13538200 9678.4 5918.1 8410.8 8499.9 8621.3 11658.9 9225.5 7218.7 10597 7990.5 FALSE FALSE TRUE 8912.344427 6429.634193 8722.511647 8464.729666 8518.496628 9240.712717 9484.342701 9419.648399 9434.535612 8268.16928 1.077910251 0.777636981 1.054950782 1.023773145 1.030276031 1.117625003 1.147091016 1.139266515 1.14106706 1 13.01335221 -5.223651187 2.555725643 1.016732395 1.143305287 0.281208904 0.088439106 0.27913204 3.556727923 0.011909055 0.034721145 5.98E-06 5.223651187 0.126572892 ALAAFLK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 ALAAFLKK 8 1 P39019;M0R2L9;M0QYF7;M0R140 P39019 RPS19 40S ribosomal protein S19 0 1 ALAAFLK(1)K 107.43 0.0026724 466210 67.616 0 0 0 130.25 182.32 146.83 198.85 0 0 FALSE TRUE FALSE 62.26412225 0 0 0 128.6968538 144.5047768 150.9496546 259.4784496 0 0 0 ALAAGADS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 ALAAGADSPK 10 0 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 0 ALAAGADS(1)PK;ALAAGADS(1)PK ; 126.71 0.0034049 88279000 8036.4 7124.7 8659.8 8026.6 9199.7 8900.8 8155.8 5788.7 8254.5 6805.5 TRUE FALSE FALSE 7400.31046 7740.527321 8980.739806 7993.388056 9089.999586 7054.673747 8384.629798 7553.647982 7349.002002 7041.990618 1.050883317 1.099195915 1.275312663 1.13510348 1.290828131 1.001801072 1.190661881 1.072658058 1.043597244 1 12.78176759 -7.199422574 2.722128899 1.022276728 1.160857047 0.328886001 0.081931942 0.206318941 2.959130462 0.01343737 0.016303168 6.32E-08 7.199422574 0.138580319 ALAAGADS(ph)PKTEEARPSPAPGPGT(ph)PTGTPTR ddPTM_HeLa_Curcumin_4h_R1 1 ALAAGADSPKTEEARPSPAPGPGTPTGTPTR 31 2 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 2 0 ALAAGADS(0.885)PKT(0.279)EEARPS(0.211)PAPGPGT(0.342)PT(0.119)GT(0.12)PT(0.046)R 40.451 0.013447 31693000 2490.6 2065.8 2365.1 2127.4 2488.4 2356.4 2086 1335.1 2717.3 2395.5 TRUE FALSE FALSE 2293.466382 2244.358547 2452.752687 2118.597382 2458.727455 1867.656078 2144.527546 1742.165844 2419.218988 2478.743447 0.925253634 0.90544205 0.989514542 0.854706196 0.991924944 0.753468892 0.865167207 0.70284234 0.975986035 1 11.27539324 -2.411324756 0.312447654 0.976314997 7.71E-16 0.634174564 0.059379969 9.574064624 0.269837759 0.020005354 4.522132834 0.003878602 2.411324756 -0.976314997 ALAAGADS(ph)PKTEEARPSPAPGPGTPTGTPTR ddPTM_HeLa_Curcumin_4h_R1 3 ALAAGADSPKTEEARPSPAPGPGTPTGTPTR 31 2 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 0 ALAAGADS(0.418)PKT(0.365)EEARPS(0.036)PAPGPGT(0.104)PT(0.022)GT(0.027)PT(0.027)R;ALAAGADS(0.767)PKT(0.223)EEARPS(0.009)PAPGPGTPTGTPTR;ALAAGADS(0.469)PKT(0.469)EEARPS(0.057)PAPGPGT(0.001)PT(0.001)GT(0.001)PT(0.001)R ;; 63.728 0.00018533 100620000 3764.58 3184.47 3528.27 3429.93 2959.04 3653.57 2863.46 3163.89 4096.13 3485.11 TRUE FALSE FALSE 3466.609521 3459.721397 3659.03079 3415.737858 2923.755381 2895.778398 2943.800981 4128.545496 3646.794787 3606.217313 0.961286916 0.959376847 1.014645118 0.947180262 0.810754075 0.802996089 0.816312697 1.144841017 1.011252088 1 11.81627062 -5.9873221 22.3550463 0.981444193 0.881372069 0.180499347 0.093811896 77.19086188 136107.2492 0.013079723 0.023690454 1.03E-06 5.9873221 -0.100072124 ALAAGADSPKT(ph)EEARPSPAPGPGTPTGTPTR ddPTM_HeLa_Curcumin_4h_R1 1 ALAAGADSPKTEEARPSPAPGPGTPTGTPTR 31 2 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 0 ALAAGADS(0.068)PKT(0.881)EEARPS(0.036)PAPGPGT(0.008)PT(0.002)GT(0.003)PT(0.003)R 63.291 0.0015268 21185000 1496.9 1242.2 1276.7 1546.7 1517.3 1526.7 1013.2 1572.5 1592.2 1495.4 TRUE FALSE FALSE 1378.418785 1349.570233 1324.015625 1540.300165 1499.207188 1210.045211 1041.627665 2051.948011 1417.539643 1547.365039 0.890816809 0.872173145 0.855658227 0.995434255 0.968877512 0.782003716 0.673162207 1.326091749 0.916099051 1 10.59559787 -9.267522244 0.995580149 1.000030029 0.907469287 0 0.163697989 1.553605016 2.760170994 0.101251693 0.027523441 5.40E-10 9.267522244 -0.092560742 ALAAGGYDVEK ddPTM_HeLa_Curcumin_4h_R1 2 ALAAGGYDVEK 11 0 P16401 P16401 HIST1H1B Histone H1.5 0 0 ; ; 180.8 1.15E-11 6458900 4901.6 3698.9 4216.1 5353.5 4855.5 6716.6 4487.4 3735.4 5434.2 4486 FALSE FALSE TRUE 4513.633188 4018.616434 4372.352375 5331.348635 4797.601334 5323.501448 4613.304367 4874.306264 4838.081856 4641.888166 0.972370084 0.865728835 0.941934019 1.148530177 1.033545222 1.14683966 0.993842204 1.050069732 1.042265923 1 12.18049605 -6.278967139 24.92584516 0.972531338 1.07181712 0.444044114 0.061230297 594.4945695 845416.3186 0.00901241 0.0137831 5.26E-07 6.278967139 0.099285782 ALADDDFLTVTGK(ac)TVR ddPTM_HeLa_Curcumin_4h_R1 1 ALADDDFLTVTGKTVR 16 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;A0A3B3IU45;E5RG31 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 0 1 ALADDDFLTVTGK(1)TVR 208.24 2.12E-71 0 170.04 162.67 0 135.35 143.2 0 0 213.37 0 0 FALSE TRUE FALSE 156.5811546 176.73047 0 134.7899576 141.4924335 0 0 278.4255308 0 0 0 ALAEEAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 ALAEEAKR 8 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 1 ALAEEAK(1)R 78.516 0.016149 1876900 1311.8 1631.8 1254.7 1111.1 1573.5 2146.8 1668.8 1371.9 1717.2 1386 FALSE TRUE FALSE 1207.969646 1772.845521 1301.200286 1106.502563 1554.73704 1701.529481 1715.622037 1790.185995 1528.827456 1434.163397 0.842281743 1.236153094 0.907288729 0.771531727 1.084072459 1.186426515 1.19625284 1.248244097 1.066006467 1 10.48599369 -5.516971386 4.906052622 0.937805076 1.200708848 0.419509443 0.122565072 0.119149477 8.067040997 0.017690669 0.038196889 3.04E-06 5.516971386 0.262903772 ALAEEAS(ph)EEELPS(ph)DVDLNDPYFAEEVK ddPTM_HeLa_Curcumin_4h_R1 3 ALAEEASEEELPSDVDLNDPYFAEEVK 27 0 Q9H501 Q9H501 ESF1 ESF1 homolog 2 0 ALAEEAS(1)EEELPS(1)DVDLNDPYFAEEVK;ALAEEAS(1)EEELPS(0.997)DVDLNDPY(0.003)FAEEVK;ALAEEAS(0.998)EEELPS(0.985)DVDLNDPY(0.017)FAEEVK ;; 121.45 2.31E-08 7897100 3035.44 2084.4 2362.89 2348.2 2622.99 3110.38 2616.75 1361.334 2700.73 2481.91 TRUE FALSE FALSE 2795.181721 2264.566248 2450.460782 2338.483771 2591.712557 2465.252127 2690.168962 1776.39847 2404.466676 2568.156188 1.088400205 0.881786808 0.954171243 0.91056914 1.009172483 0.959930762 1.047509873 0.691701883 0.936261855 1 11.32651723 -7.262741447 24.99999871 1.041744541 0.932533849 0.106044949 0.098191365 123.8817778 2378547.42 0.014907963 0.017558329 5.46E-08 7.262741447 -0.109210692 ALAEEASEEELPS(ph)DVDLNDPYFAEEVK ddPTM_HeLa_Curcumin_4h_R1 3 ALAEEASEEELPSDVDLNDPYFAEEVK 27 0 Q9H501 Q9H501 ESF1 ESF1 homolog 1 0 ALAEEASEEELPS(0.999)DVDLNDPY(0.001)FAEEVK;ALAEEAS(0.159)EEELPS(0.841)DVDLNDPYFAEEVK;ALAEEASEEELPS(0.801)DVDLNDPY(0.199)FAEEVK ;; 94.087 2.23E-06 19617100 3880.92 3298.93 3678.27 3759.25 3859.25 4603.35 3975.62 2642.29 4191.82 3689.11 TRUE FALSE FALSE 3573.741087 3584.074809 3814.589922 3743.69522 3813.230964 3648.56332 4087.165197 3447.912057 3731.987833 3817.306298 0.936194481 0.938901552 0.999288405 0.980716486 0.998932406 0.955795274 1.070693541 0.9032317 0.977649563 1 11.89833924 -6.725681631 24.9995446 0.966705096 0.987823231 0.052510864 0.042762888 458.1915511 320337.1678 0.006731179 0.009519148 1.88E-07 6.725681631 0.021118135 ALAENSGVK ddPTM_HeLa_Curcumin_4h_R1 1 ALAENSGVK 9 0 P50990-2;P50990;P50990-3;H7C2U0 P50990-2 CCT8 T-complex protein 1 subunit theta 0 0 136.57 0.0002432 4177400 4413.9 3573.6 3546.6 3536.5 3710.2 4371.4 3329.8 3050 4052.4 4150.6 FALSE FALSE TRUE 4064.535157 3882.48606 3678.040116 3521.8669 3665.958288 3464.722364 3423.225226 3979.93096 3607.861859 4294.833041 0.946377919 0.903989986 0.856387217 0.82002417 0.853574109 0.806718755 0.797056648 0.926678854 0.840047058 1 12.06838633 -7.19108761 0.945079241 0.984577661 0.834068465 0.175904307 0.057426984 0.162631417 0.287526846 0.007518954 0.009287282 6.44E-08 7.19108761 -0.150509195 ALAITSK(ac)APPAK ddPTM_HeLa_Curcumin_4h_R1 2 ALAITSKAPPAK 12 1 Q92541 Q92541 RTF1 RNA polymerase-associated protein RTF1 homolog 0 1 ; ALAITSK(1)APPAK;ALAITSK(1)APPAK 149.23 5.43E-05 6466100 9977.7 8814 7401.8 7028.5 7029.9 11702.5 7383.1 7578.9 8774.4 8670.7 FALSE TRUE FALSE 9187.954517 9575.842886 7676.117219 6999.417929 6946.073034 9275.269586 7590.249915 9889.671721 7811.870272 8972.00618 1.024069125 1.067302306 0.855563078 0.780139669 0.774193965 1.03380107 0.845992497 1.102280975 0.870693813 1 13.1312149 -6.757057312 24.99906089 1.01587878 0.891365492 0.127988206 0.108745759 110.3674081 629626.7865 0.015166391 0.021029902 1.75E-07 6.757057312 -0.124513288 ALANSLACQGK ddPTM_HeLa_Curcumin_4h_R1 3 ALANSLACQGK 11 0 P04075;J3KPS3;P04075-2;H3BR68 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 ;; ;; 202.2 1.40E-33 12281000 8066.1 6151.6 6751.3 7010.5 6572.2 9286.2 6239.5 6610.9 7577.7 7100.9 FALSE FALSE TRUE 7427.659674 6683.316893 7001.509117 6981.492409 6493.830807 7360.137443 6414.563577 8626.532977 6746.445268 7347.655746 1.010888361 0.909584924 0.952890195 0.950165964 0.883796279 1.001698732 0.873008181 1.174052415 0.918176559 1 12.84306832 -7.310738636 24.91305792 1.005141736 0.957582627 0 0.084501996 693.4874762 350447.9439 0.012243863 0.014001382 4.89E-08 7.310738636 -0.047559108 ALAPEYAK ddPTM_HeLa_Curcumin_4h_R1 1 ALAPEYAK 8 0 P07237;H7BZ94;I3L3U6;I3NI03;I3L514;I3L0S0 P07237 P4HB Protein disulfide-isomerase 0 0 96.492 0.016626 4883500 9624.2 8147.3 8957.8 8429.8 8928 9811 7811.4 6078.7 9280.8 8800.2 FALSE FALSE TRUE 8862.434415 8851.516308 9289.783948 8394.919721 8821.539431 7776.088007 8030.566861 7932.067647 8262.719459 9106.006295 0.973251514 0.972052514 1.020182026 0.92191016 0.968760524 0.85395153 0.881897794 0.871080844 0.907392241 1 13.15260274 -5.498879399 1.321113907 0.987056659 0.86592461 0.560630952 0.036198344 0.142290815 0.475729371 0.003802379 0.012441363 3.17E-06 5.498879399 -0.121132048 QPVGGGQK(ac)LLTR ddPTM_HeLa_Curcumin_4h_R1 2 QPVGGGQKLLTR 12 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 1 ; QPVGGGQK(1)LLTR;QPVGGGQK(1)LLTR 147.62 6.64E-05 61729000 481.04 431.48 494.57 526.17 772.65 988.17 797.78 832.12 623.16 428.52 FALSE TRUE FALSE 442.9651764 468.7752086 512.8991993 523.992848 763.4366534 783.212403 820.1635597 1085.829557 554.8009071 443.4110381 0.998994473 1.057202388 1.156712745 1.181731628 1.721735789 1.766334926 1.849668793 2.448810391 1.251211313 1 8.792500874 -4.648236464 0.514690056 0.978515978 2.946485705 0.906401743 0.139814374 0.430796263 0.098080173 0.022765859 0.47158098 2.25E-05 4.648236464 1.967969727 up ALDDTAR ddPTM_HeLa_Curcumin_4h_R1 1 ALDDTAR 7 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 0 0 105.39 0.016924 1397200 1483.4 2168.7 1600.6 1387.8 1209 1558.4 1115.9 867.63 1598.8 1798.9 FALSE FALSE TRUE 1365.987325 2356.152764 1659.919644 1382.057651 1194.583465 1235.170273 1147.209151 1132.166393 1423.41564 1861.411641 0.733844838 1.265788132 0.891753123 0.742478247 0.641762111 0.663566428 0.616311366 0.608229995 0.764696862 1 10.86218142 -6.066476939 2.85072275 0.907583341 0.634779474 0.510933543 0.137746772 0.205599271 3.291027212 0.023362941 0.042111009 8.58E-07 6.066476939 -0.272803866 ALDEGDIALLK ddPTM_HeLa_Curcumin_4h_R1 1 ALDEGDIALLK 11 0 P35998;C9JLS9 P35998 PSMC2 26S protease regulatory subunit 7 0 0 147.75 1.16E-05 1145600 1175.4 1136.4 1027.6 1117.4 1133.4 1349.8 1178.3 1035.5 1217.8 1169.2 FALSE FALSE TRUE 1082.36585 1234.625352 1065.68376 1112.776495 1119.884945 1069.836265 1211.359927 1351.219183 1084.210387 1209.829613 0.894643211 1.020495233 0.880854418 0.919779515 0.925655095 0.884286724 1.0012649 1.116867341 0.896167836 1 10.24058816 -4.373186859 3.246902778 0.941820484 1.123245392 0.593583285 0.046998598 0.167907151 2.822302013 0.007148993 0.063847655 4.23E-05 4.373186859 0.181424908 ALDEYYDKHFTEFVPLR ddPTM_HeLa_Curcumin_4h_R1 1 ALDEYYDKHFTEFVPLR 17 1 P38606-2;P38606 P38606-2 ATP6V1A V-type proton ATPase catalytic subunit A 0 0 77.068 0.0054126 13086000 1949.9 1681.4 1221.7 1365.6 1661 2153.9 1502 1451.2 1917.6 1622.1 FALSE FALSE TRUE 1795.563357 1826.732724 1266.977277 1359.949509 1641.19366 1707.156861 1544.142078 1893.664199 1707.244078 1678.467854 1.069763328 1.088333458 0.75484155 0.810232681 0.977792727 1.017092378 0.919971195 1.128209989 1.01714434 1 10.71292919 ALDFIASK ddPTM_HeLa_Curcumin_4h_R1 2 ALDFIASK 8 0 O43707;G3V2E8;P12814-4;P12814-3;P12814;P12814-2;H9KV75;G3V2N5;G3V5M4;G3V2W4;G3V2X9;A0A087WSZ2;Q08043 O43707;P12814-4 ACTN4;ACTN1;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-3 0 0 ; ; 111.95 0.0054204 9595100 9409 7141.4 9202.1 8569.7 9587.5 9890.4 9753.6 9277.5 8653.5 7611.2 FALSE FALSE TRUE 8664.267722 7758.670795 9543.137921 8534.240852 9473.175324 7839.019552 10027.25977 12106.16704 7704.2327 7875.688633 1.100128271 0.985141891 1.211721078 1.083618367 1.202837716 0.995344016 1.273191492 1.537156635 0.978229722 1 12.94319036 -1.000000172 0.779249613 1.05865109 107.8355546 0.737561773 0.085707362 150.4722312 0.538825479 0.013143364 28325.52639 0.09999996 1.000000172 106.7769035 ALDGAFTEENR ddPTM_HeLa_Curcumin_4h_R1 3 ALDGAFTEENR 11 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 ;; ;; 151.83 0.0013756 22839300 3523.7 3034.19 2779.84 3365.21 2985.73 3423.6 2873.04 2595.63 3786.63 3032.84 FALSE FALSE TRUE 3244.795427 3296.451864 2882.863316 3351.285653 2950.12712 2713.506768 2953.64977 3387.025638 3371.246163 3138.230964 1.033956858 1.050417226 0.918626879 1.06789006 0.940060548 0.864661269 0.941183043 1.079278637 1.074250494 1 11.61573582 -5.732442312 24.99522306 1.014397301 0.948671019 0.19719779 0.064613739 253.2408001 218290.2035 0.008615227 0.01722817 1.85E-06 5.732442312 -0.065726282 ALDGEES(ph)DFEDYPMR ddPTM_HeLa_Curcumin_4h_R1 1 ALDGEESDFEDYPMR 15 0 Q8IX90-3;Q8IX90 Q8IX90-3 SKA3 Spindle and kinetochore-associated protein 3 1 0 ALDGEES(1)DFEDYPMR 82.483 0.013804 1881800 295.33 320.73 269.21 381.05 350 590.83 320.88 186.55 296.31 208.26 TRUE FALSE FALSE 271.9543189 348.4524721 279.1871594 379.4733161 345.8264786 468.285198 329.8830292 243.4282362 263.8055343 215.4970195 1.261986451 1.61697119 1.295549981 1.760921413 1.604785437 2.173047215 1.53080089 1.129613007 1.224172543 1 7.751524106 -7.493063789 0.721293886 1.047769626 1.649631215 0.343412517 0.267795355 0.385335186 0.430876574 0.075746134 0.077147456 3.21E-08 7.493063789 0.601861589 ALDIDS(ph)DEESEPK ddPTM_HeLa_Curcumin_4h_R1 4 ALDIDSDEESEPK 13 0 Q96DR7-3;Q96DR7-4;Q96DR7 Q96DR7-3 ARHGEF26 Rho guanine nucleotide exchange factor 26 1 0 ALDIDS(1)DEESEPK;ALDIDS(1)DEESEPK;ALDIDS(0.995)DEES(0.005)EPK;ALDIDS(0.999)DEES(0.001)EPK ;;; 255.85 3.77E-36 30801100 15216.5 13261.7 15715.4 14603.9 16808.6 16229.5 13321.6 11686.1 13471.8 12779.7 TRUE FALSE FALSE 14012.09797 14407.98226 16297.82655 14543.47293 16608.16842 12863.31876 13695.36824 15249.13809 11993.97724 13223.79362 1.059612572 1.089549842 1.232462258 1.099795818 1.255930703 0.972740435 1.035661069 1.153159111 0.90699973 1 13.69084849 -7.645483219 1.379691213 1.01829962 1.119245679 0.314863338 0.086909063 0.409301829 1.599511256 0.017228865 0.017319602 2.26E-08 7.645483219 0.10094606 ALDIDS(ph)DEESEPKEQK ddPTM_HeLa_Curcumin_4h_R1 1 ALDIDSDEESEPKEQK 16 1 Q96DR7-3;Q96DR7-4;Q96DR7 Q96DR7-3 ARHGEF26 Rho guanine nucleotide exchange factor 26 1 0 ALDIDS(0.997)DEES(0.003)EPKEQK 114.28 0.0005702 26348000 4067.3 4004.9 3286.1 4109.3 3941.9 4033.9 3528.1 3234.3 4752.8 3367.3 TRUE FALSE FALSE 3745.368913 4351.065711 3407.885757 4092.296805 3894.895417 3197.223669 3627.088991 4220.423181 4231.429731 3484.313424 1.074923079 1.248758415 0.978065214 1.174491588 1.117837273 0.917605071 1.040976671 1.211263933 1.214422819 1 11.76665869 -8.648835478 1.045904743 1.008321361 1.09015504 0 0.116255401 0.779223099 1.717986854 0.034873633 0.018493995 2.24E-09 8.648835478 0.081833679 ALDISLS(ph)S(ph)GEEDEGDEEDSTAGTTK ddPTM_HeLa_Curcumin_4h_R1 1 ALDISLSSGEEDEGDEEDSTAGTTK 25 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 2 0 ALDIS(0.047)LS(0.968)S(0.91)GEEDEGDEEDS(0.062)T(0.012)AGT(0.001)TK 98.839 1.45E-05 9212700 8660.1 8253 9410.9 9364.8 11055 9975.9 8284.7 5872 8777.9 7344.4 TRUE FALSE FALSE 7974.643947 8966.352545 9759.676233 9326.050939 10923.17635 7906.785888 8517.146385 7662.345769 7814.986331 7599.617353 1.049348089 1.179842633 1.284232584 1.227173752 1.437332413 1.040418948 1.120733583 1.008254154 1.02833945 1 12.89171106 -7.310043758 3.296306358 1.020938373 1.193475119 0.288987468 0.115081948 0.227612266 4.865094104 0.020746347 0.024064417 4.90E-08 7.310043758 0.172536746 ALDISLSS(ph)GEEDEGDEEDST(ph)AGTTK ddPTM_HeLa_Curcumin_4h_R1 1 ALDISLSSGEEDEGDEEDSTAGTTK 25 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 2 0 ALDIS(0.029)LS(0.53)S(0.569)GEEDEGDEEDS(0.342)T(0.413)AGT(0.097)T(0.02)K 52.483 0.014122 7802200 2088.5 1977.5 2420.6 2406.6 2270.9 2654.2 2287.5 1615.4 2224.8 1664.9 TRUE FALSE FALSE 1923.193021 2148.426288 2510.309565 2396.642127 2243.821001 2103.689001 2351.681094 2107.928024 1980.745006 1722.755151 1.116347277 1.247087427 1.457148199 1.391168168 1.30246077 1.221118973 1.365069837 1.22357958 1.149754221 1 10.75050196 -7.345880831 1.906824808 1.044360228 1.326490928 0.641029369 0.078282827 0.122750537 0.847818334 0.014538291 0.016705603 4.51E-08 7.345880831 0.2821307 ALDLDSSCK ddPTM_HeLa_Curcumin_4h_R1 1 ALDLDSSCK 9 0 P31948;P31948-2;P31948-3;H0YGI8 P31948 STIP1 Stress-induced-phosphoprotein 1 0 0 114.89 0.0020241 5816300 2953.7 3678.8 3158.7 3401.4 3401.6 4700.3 3978.6 3306.3 3321.4 2682.7 FALSE FALSE TRUE 2719.911528 3996.77908 3275.764201 3387.325908 3361.038142 3725.404797 4090.228808 4314.37565 2957.05073 2775.923625 0.979822176 1.439801529 1.180062798 1.220251839 1.210781922 1.342041533 1.473465902 1.554212663 1.065249311 1 11.43875216 -2.984163161 0.212214541 0.928099506 2.554524185 0.649615783 0.112903134 8.71704392 0.213445282 0.110494898 4.08051834 0.001037139 2.984163161 1.62642468 S(ph)PVPAQIAITVPK ddPTM_HeLa_Curcumin_4h_R1 2 SPVPAQIAITVPK 13 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 0 S(1)PVPAQIAITVPK;S(1)PVPAQIAITVPK ; 169.94 0.00019443 466400000 9354.2 7767 8229.6 8250.2 7127.7 5036.6 2781.7 2270.7 8164.2 8020.3 TRUE FALSE FALSE 8613.805199 8438.344871 8534.596215 8216.062858 7042.706833 3991.952386 2859.747015 2963.025977 7268.607686 8299.004828 1.037932304 1.01678997 1.028387908 0.990005793 0.848620645 0.481015793 0.34458915 0.35703389 0.875840879 1 13.01872263 -5.290593966 1.889164904 1.018754242 0.341553391 0.970355342 0.047005013 0.013906783 0.094747905 0.002597749 0.008192496 5.12E-06 5.290593966 -0.677200851 down ALDQASEEIWNDFR ddPTM_HeLa_Curcumin_4h_R1 2 ALDQASEEIWNDFR 14 0 G3V1U3;F8VQZ7;P50579-3;P50579;F8VZX9;F8VY03;F8VRR3;P50579-2 G3V1U3 METAP2 Methionine aminopeptidase 2 0 0 ; ; 251.24 5.91E-81 2477300 1271.37 1091.43 1475.91 1472.35 1369.12 1556.76 1206.57 930.04 1354.66 1079.89 FALSE FALSE TRUE 1170.739723 1185.768346 1530.608523 1466.257806 1352.794138 1233.870428 1240.423107 1213.604915 1206.057187 1117.416097 1.047720474 1.061169916 1.3697749 1.312186042 1.210644935 1.104217517 1.110081652 1.086081468 1.079326842 1 10.12595079 -6.977184126 24.88759362 1.024214153 1.197793151 0.418100617 0.087140181 154.8952289 168959.5511 0.01511507 0.019864426 1.05E-07 6.977184126 0.173578998 ALDSNS(ph)LENDDLSAPGR ddPTM_HeLa_Curcumin_4h_R1 2 ALDSNSLENDDLSAPGR 17 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 0 ALDS(0.101)NS(0.899)LENDDLSAPGR;ALDS(0.013)NS(0.983)LENDDLS(0.004)APGR ; 208.62 5.99E-11 10574700 2417.28 2054.61 2612.96 2213.46 2955.91 2760.44 2080.25 1904.03 2015.02 2094.64 TRUE FALSE FALSE 2225.949737 2232.201333 2709.798596 2204.301289 2920.662704 2187.893627 2138.616216 2484.559982 1793.977347 2167.428584 1.027000268 1.029884606 1.250236624 1.017012189 1.347524308 1.009442084 0.986706659 1.146316885 0.827698481 1 11.08176874 -6.970036143 24.99098918 1.013576002 1.121355146 0.259007177 0.120350815 241.6271794 201525.697 0.016057743 0.021103843 1.07E-07 6.970036143 0.107779145 ALDVSAS(ph)DDEIAR ddPTM_HeLa_Curcumin_4h_R1 2 ALDVSASDDEIAR 13 0 C9JLK2;H7C393;H7C1U0;C9JIF9;P13798 C9JLK2 APEH Acylamino-acid-releasing enzyme 1 0 ALDVS(0.352)AS(0.648)DDEIAR;ALDVS(0.371)AS(0.629)DDEIAR ; 198.37 1.84E-06 88313000 3903.4 2645 3367.9 3126.8 2960.9 5304.9 2770.6 2219.32 3522.4 2839.7 TRUE FALSE FALSE 3594.441771 2873.622014 3492.717337 3113.86213 2925.593201 4204.603941 2848.335579 2895.980452 3136.001533 2938.379364 1.223273555 0.977961542 1.188654324 1.059720936 0.995648567 1.430926174 0.96935597 0.985570647 1.067255499 1 11.52080495 -9.701553547 1.594306725 1.000086477 1.123741291 0.015975009 0.140348329 0.75342781 3.45782332 0.096632523 0.021383939 1.99E-10 9.701553547 0.123654814 ALEAELDAQHLSETFDNIDNLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 ALEAELDAQHLSETFDNIDNLSPK 24 0 P25054-2;P25054-3;P25054;A0A2Q2SV78;E9PFT7 P25054-2 APC Adenomatous polyposis coli protein 1 0 ALEAELDAQHLSETFDNIDNLS(1)PK;ALEAELDAQHLSETFDNIDNLS(1)PK ; 138.78 1.18E-06 7145900 1873.98 2054.44 1646.67 1650.45 2501 4370.1 1519.97 520.44 2996.4 1678.06 TRUE FALSE FALSE 1725.652506 2232.016639 1707.697039 1643.620875 2471.177208 3463.691999 1562.616267 679.1197602 2667.702417 1736.37246 0.993826236 1.285448077 0.983485443 0.946583128 1.42318383 1.994786302 0.899931497 0.391114105 1.536365312 1 10.76186073 -7.306690932 21.57993662 0.997084436 1.154675699 0 0.425012518 295.3514015 140848.2875 0.068062312 0.077832082 4.94E-08 7.306690932 0.157591263 ALEATTEHIR ddPTM_HeLa_Curcumin_4h_R1 1 ALEATTEHIR 10 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 139.43 0.0001205 0 2767.7 2234.6 2360.7 2682.4 3033.2 2993.4 2332.1 2231.5 2623.7 2225.2 FALSE FALSE TRUE 2548.633625 2427.748867 2448.189619 2671.30094 2997.031071 2372.535097 2397.532449 2911.874077 2335.886674 2302.525534 1.10688615 1.054385209 1.063262744 1.160161266 1.301627724 1.030405553 1.041262046 1.264643555 1.014488934 1 11.16900144 -13.52287514 0.11995494 0.552394044 1.196377754 0.290812413 0.084350531 93.11396933 0.806742277 10.00409345 0.405879016 3.00E-14 13.52287514 0.64398371 ALEEALEAKEEFER ddPTM_HeLa_Curcumin_4h_R1 2 ALEEALEAKEEFER 14 1 P35580;P35580-5;P35580-2;P35580-3;P35580-4 P35580 MYH10 Myosin-10 0 0 ; ; 144.51 0.00056298 2131200 1516.57 1523.57 1629.02 1399.46 1360.31 1567.57 1661.51 1176.75 1693.25 1896.29 FALSE FALSE TRUE 1396.531884 1655.260602 1689.392914 1393.669405 1344.089192 1242.438312 1708.127499 1535.535658 1507.504711 1962.185936 0.711722502 0.843579893 0.860974938 0.710263681 0.684995834 0.633190917 0.870522751 0.782563787 0.768278216 1 10.93824604 -9.410523308 0.78416893 1.025859653 0.757729149 0 0.103769167 0.49918549 0.460184348 0.089127816 0.015598733 3.89E-10 9.410523308 -0.268130504 ALEEAMEQK ddPTM_HeLa_Curcumin_4h_R1 2 ALEEAMEQK 9 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ; ; 122.13 0.001872 4256600 1446.59 1029.55 1132.39 1198.88 1020.75 1353.56 997.92 974.8 1366.51 1372.26 FALSE FALSE TRUE 1332.090875 1118.539714 1174.35737 1193.919352 1008.578223 1072.816398 1025.918949 1272.012033 1216.607272 1419.945933 0.938127885 0.787734018 0.827043722 0.840820291 0.710293399 0.755533273 0.722505643 0.89581723 0.856798307 1 10.47162028 -7.330521507 0.9755846 0.985036078 0.775366536 0.404251879 0.068544075 0.176831774 0.335016173 0.01208303 0.013863235 4.67E-08 7.330521507 -0.209669542 ALEEGDGSVSGSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 ALEEGDGSVSGSSPR 15 0 Q8N3X1-2;Q8N3X1 Q8N3X1-2 FNBP4 Formin-binding protein 4 1 0 ALEEGDGSVSGS(0.047)S(0.953)PR;ALEEGDGSVSGSS(1)PR ; 305.98 1.91E-92 547300000 3424.3 2936.9 3008.1 2677.8 3256 4157.7 3424.9 2517.2 3356.4 2901 TRUE FALSE FALSE 3153.263042 3190.752549 3119.582832 2666.719973 3217.174327 3295.346153 3520.993476 3284.682692 2988.211317 3001.809534 1.05045407 1.062943039 1.039234101 0.888370812 1.071744989 1.097786557 1.17295699 1.094234213 0.995469993 1 11.55161672 -5.326543313 3.189434564 1.019636829 1.12966596 0.491690835 0.05123425 0.168574956 3.369130562 0.007377426 0.018582056 4.71E-06 5.326543313 0.110029131 ALEENNNFSK ddPTM_HeLa_Curcumin_4h_R1 2 ALEENNNFSK 10 0 E5RGX5;Q93045;Q93045-2 E5RGX5 STMN2 Stathmin;Stathmin-2 0 0 ; ; 187.99 1.57E-16 19376700 4472.5 3572.9 3780.9 3956.9 3723.4 4567.2 3662.8 3790.9 4328.7 3657.4 FALSE FALSE TRUE 4118.496906 3881.725555 3921.02348 3940.527396 3679.000887 3619.911237 3765.56831 4946.727959 3853.85244 3784.494378 1.088255522 1.025691986 1.036075916 1.041229555 0.972124812 0.956511194 0.99499905 1.307104058 1.018326903 1 11.88588485 -4.2572187 24.72802331 1.028335505 1.307104187 0.841659618 0.037624909 136.9433898 802285.104 0.006601273 0.068436501 5.53E-05 4.2572187 0.278768682 ALEESESSQLIS(ph)PPLAQAIR ddPTM_HeLa_Curcumin_4h_R1 2 ALEESESSQLISPPLAQAIR 20 0 P42166 P42166 TMPO "Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin" 1 0 ALEES(0.193)ES(0.007)S(0.007)QLIS(0.792)PPLAQAIR;ALEESESSQLIS(1)PPLAQAIR ; 244.18 7.55E-34 12642100 2062.16 1540.01 1580.62 1801.61 1746.05 4011.6 3458.8 1198.94 2010.55 1541.31 TRUE FALSE FALSE 1898.93786 1673.121602 1639.199168 1794.155415 1725.229494 3179.54894 3555.844619 1564.491287 1789.997695 1594.870408 1.190653391 1.049064296 1.027794584 1.124953731 1.081736476 1.99360959 2.229550816 0.980951982 1.122346798 1 10.63922349 -5.272193954 24.43058663 1.086234997 1.78418879 0.490270123 0.302217456 272.0278844 617951.5607 0.039651426 0.089543314 5.34E-06 5.272193954 0.697953793 ALEIIPR ddPTM_HeLa_Curcumin_4h_R1 2 ALEIIPR 7 0 Q99832-3;Q99832;Q99832-2;Q99832-4 Q99832-3 CCT7 T-complex protein 1 subunit eta 0 0 ; ; 128.48 0.0085975 8998600 6382.2 5217 6023.5 6245.4 5877.8 6828.3 5060.2 5676.3 6430.6 5768.9 FALSE FALSE TRUE 5877.042136 5667.934233 6246.736209 6219.55819 5807.711074 5412.033609 5202.175593 7406.97774 5725.179269 5969.368846 0.984533254 0.949503102 1.046465107 1.041912194 0.972918783 0.906634143 0.87147833 1.240830971 0.959092899 1 12.54336268 -4.245032022 24.66741733 0.983429449 1.240831209 0.697060082 0.052871397 1250.855867 1880547.632 0.00741365 0.266040206 5.69E-05 4.245032022 0.25740176 ALELDSNLY(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 ALELDSNLYR 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 0 ALELDSNLY(1)R 154.01 1.43E-06 0 2076.3 1913 1515.1 1859.8 1603 2020.8 1567.1 1412 1859.6 1945.3 TRUE FALSE FALSE 1911.958664 2078.351196 1571.250939 1852.10464 1583.885272 1601.663301 1611.068608 1842.5123 1655.606532 2012.89903 0.949853239 1.032516368 0.780591036 0.920118005 0.786867721 0.795699773 0.800372291 0.91535257 0.822498549 1 10.97505909 -6.761107602 24.99999999 0.979872688 0.831820994 0.373576451 0.071103615 3.82337468 288080.3732 0.007859088 0.01072579 1.73E-07 6.761107602 -0.148051693 ALELDSNLYR ddPTM_HeLa_Curcumin_4h_R1 3 ALELDSNLYR 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ;; ;; 192.91 9.97E-06 27408800 7483.6 6508.6 7252.1 6760.1 7290.7 8049.8 6709.6 5727.9 7192.2 6739.5 FALSE FALSE TRUE 6891.265163 7071.174382 7520.869206 6732.128497 7203.763164 6380.18074 6897.853318 7474.310342 6403.233654 6973.697123 0.98817959 1.013977845 1.078462267 0.965360035 1.032990541 0.914892148 0.989124305 1.071785914 0.918197843 1 12.76770799 -4.257961359 23.76539103 0.996288947 1.071785971 0.203833559 0.047141788 179.8271386 1228645.004 0.005205799 0.049982082 5.52E-05 4.257961359 0.075497024 ALELDSNNEK ddPTM_HeLa_Curcumin_4h_R1 1 ALELDSNNEK 10 0 Q02790 Q02790 FKBP4 "Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed" 0 0 136.96 0.0004127 0 1595.5 1387.8 1600.7 1991.9 1514.3 1260.1 821.43 1260.2 1833.7 1432.7 FALSE FALSE TRUE 1469.214491 1507.755248 1660.02335 1983.658046 1496.242962 998.7410557 844.477115 1644.429179 1632.547698 1482.486218 0.991047656 1.017045035 1.119756345 1.338061711 1.009279508 0.673693316 0.569635727 1.109237414 1.101222849 1 10.53380298 -5.315454354 7.756593711 1.034259317 0.763046486 0.382566349 0.165282276 0.235590956 30.87787677 0.023248242 0.052343274 4.84E-06 5.315454354 -0.271212831 ALELEQER ddPTM_HeLa_Curcumin_4h_R1 1 ALELEQER 8 0 P26038 P26038 MSN Moesin 0 0 115.49 0.0034503 9321000 2934.2 2432.5 2589.9 2587.8 2574.3 3632.3 2680.7 3030.4 3146.8 2944.6 FALSE FALSE TRUE 2701.954974 2642.754461 2685.883972 2577.092369 2543.603154 2878.920036 2755.913227 3954.35501 2801.603913 3046.924631 0.886781034 0.867351438 0.881506535 0.845801154 0.834810001 0.944860928 0.904490121 1.297818453 0.919485794 1 11.5731381 -4.260051539 24.92418174 0.919547484 1.297818581 0.847043153 0.050203837 43.78268828 786204.9054 0.009176519 0.077014036 5.49E-05 4.260051539 0.378271097 ALELPLAASSIPRPRT(ph)PS(ph)PESHR ddPTM_HeLa_Curcumin_4h_R1 1 ALELPLAASSIPRPRTPSPESHR 23 2 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 2 0 ALELPLAAS(0.364)S(0.364)IPRPRT(0.403)PS(0.62)PES(0.248)HR 44.648 0.016104 16727000 1711.6 1362.9 1328.3 1606.3 1394.1 1799.6 1467.6 1419.6 1903.3 1742.5 TRUE FALSE FALSE 1576.125054 1480.703003 1377.527966 1599.653556 1377.476268 1426.342674 1508.776906 1852.429505 1694.512752 1803.051745 0.874142996 0.821220471 0.763998022 0.887192262 0.763969349 0.791071403 0.836790686 1.027385659 0.939802619 1 10.81622509 -8.560311195 0.751384407 0.993042848 0.836823774 0.2977156 0.074505587 0.450975147 0.520248524 0.035416365 0.016152758 2.75E-09 8.560311195 -0.156219074 ALELTGLK ddPTM_HeLa_Curcumin_4h_R1 2 ALELTGLK 8 0 P19338 P19338 NCL Nucleolin 0 0 ; ; 138.83 7.52E-09 7821400 11181.7 8960.4 9638.9 9467.3 9804.6 13155.5 9627.5 10232.4 10849.1 9433.3 FALSE FALSE TRUE 10296.65665 9734.897049 9996.126113 9428.126821 9687.686549 10426.90101 9897.621739 13352.21166 9658.980873 9761.106473 1.054865724 0.997314913 1.024077152 0.9658871 0.992478319 1.06820892 1.013985634 1.367899397 0.989537498 1 13.25282898 -4.260800857 24.93926919 1.020356756 1.367899507 0.92518799 0.030289328 10.03911748 392014.4484 0.004394048 0.034856201 5.49E-05 4.260800857 0.347542751 ALENDFFNS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 4 ALENDFFNSPPR 12 0 F5H148;H3BMT1;Q9NYV6-2;Q9NYV6;A6NIE6;Q9NYV6-3 F5H148 RRN3;RRN3P2 RNA polymerase I-specific transcription initiation factor RRN3;Putative RRN3-like protein RRN3P2 1 0 ALENDFFNS(1)PPR;ALENDFFNS(1)PPR;ALENDFFNS(1)PPR;ALENDFFNS(1)PPR ;;; 121.56 0.0034061 41567400 6580.2 5851 5910.6 5779.9 5671.4 6545.59 4772.53 3137.57 6819.4 6361.2 TRUE FALSE FALSE 6059.370227 6356.734368 6129.652035 5755.984305 5603.772259 5187.96085 4906.434347 4094.200649 6071.328881 6582.251227 0.920561981 0.965738643 0.931239454 0.874470467 0.851345849 0.788174239 0.745403689 0.622006136 0.922378784 1 12.68436538 -3.198470596 0.347679743 0.977787191 3.62E-19 0.946554189 0.02517521 1.785650656 0.086172813 0.007916983 0.855090111 0.000633183 3.198470596 -0.977787191 VS(ph)EFS(ph)VS(ph)SEGS(ph)GEK ddPTM_HeLa_Curcumin_4h_R1 1 VSEFSVSSEGSGEK 14 0 Q5TAP6 Q5TAP6 UTP14C U3 small nucleolar RNA-associated protein 14 homolog C 4 0 VS(1)EFS(1)VS(0.509)S(0.509)EGS(0.981)GEK 81.327 0.0062077 2657800 1181.7 1434.6 1069.5 1563.2 1198.1 658.2 491.66 476.44 1183.2 1267.7 TRUE FALSE FALSE 1088.167198 1558.600432 1109.136611 1556.731893 1183.81344 521.6819006 505.4546564 621.7043627 1053.40592 1311.752481 0.829552232 1.188181806 0.845538032 1.186757346 0.902467087 0.397698429 0.385327769 0.473949447 0.803052356 1 10.3572798 -5.284434908 5.659196272 0.953383978 0.413630775 0.789118204 0.129383599 0.055902186 6.089471764 0.01778996 0.041842648 5.19E-06 5.284434908 -0.539753203 down ALENDPDCR ddPTM_HeLa_Curcumin_4h_R1 1 ALENDPDCR 9 0 P13797;A0A0A0MSQ0;P13797-3;P13797-2;U3KQI3;P13796;Q5TBN3 P13797 PLS3;LCP1 Plastin-3;Plastin-2 0 0 141.52 0.019446 30094000 4219.8 2976.1 3765.3 2858.4 4287.4 4725.7 3353.8 3850.5 3118.6 2988.3 FALSE FALSE TRUE 3885.798377 3233.340823 3904.84533 2846.572698 4236.275555 3745.53655 3447.898602 5024.499724 2776.497382 3092.143203 1.256668311 1.045663351 1.262828102 0.920582428 1.370012732 1.211307596 1.115051398 1.624924654 0.897920051 1 11.59439142 ALEQQVEEMK ddPTM_HeLa_Curcumin_4h_R1 1 ALEQQVEEMK 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 179.42 1.10E-15 3173300 1506.5 1311.4 1481.9 1372.8 1611.6 1746.7 1486.3 1476.5 1409.7 1253.3 FALSE FALSE TRUE 1387.258935 1424.751573 1536.820518 1367.119717 1592.382723 1384.414731 1528.001578 1926.678053 1255.059437 1296.852082 1.069712541 1.098623037 1.185039172 1.054183231 1.227883076 1.06751938 1.178238906 1.485657524 0.967773777 1 10.34079822 -1 0.527369265 1.047411383 16.00363598 0.710617652 0.075847669 42.31641795 0.377460925 0.014062778 713.8875881 0.1 1 14.9562246 ALES(ph)PERPFLAILGGAK ddPTM_HeLa_Curcumin_4h_R1 1 ALESPERPFLAILGGAK 17 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 1 0 ALES(1)PERPFLAILGGAK 120.99 0.0057592 808930000 886.41 887.29 1038.9 822.74 1067.9 1328.5 1033.8 1156.9 1439.1 945.76 TRUE FALSE FALSE 816.2497132 963.9833939 1077.402548 819.3357199 1055.16599 1052.954125 1062.805646 1509.633484 1281.23433 978.6250896 0.834078057 0.985038504 1.100934933 0.837231467 1.07821269 1.075952513 1.086019209 1.542606561 1.309218764 1 9.93461246 -1.000000008 0.718746683 0.935987496 84.75010969 0.465829995 0.146471218 101.9891037 0.469363533 0.015597108 13796.39512 0.099999998 1.000000008 83.81412219 ALESPERPFLAILGGAK ddPTM_HeLa_Curcumin_4h_R1 2 ALESPERPFLAILGGAK 17 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 0 ; ; 165.86 0.00011549 22833300 3054.61 3221.44 3205.32 2821.11 2445.12 3407.81 3241.78 2773.16 3421.61 3594.04 FALSE FALSE TRUE 2812.834395 3499.886919 3324.111979 2809.436994 2415.963541 2700.991792 3332.735622 3618.683718 3046.267943 3718.932622 0.756355299 0.941099846 0.893834957 0.755441757 0.649638965 0.726281454 0.896153805 0.973043635 0.819124263 1 11.86067289 -9.446656676 1.002617057 1.007871374 0.815111951 0 0.112356466 0.610911224 1.023013782 0.089686884 0.018926374 3.58E-10 9.446656676 -0.192759423 ALEVAGPDGQASAISPAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 ALEVAGPDGQASAISPASPR 20 0 K7EIN8;Q0VDD7-2;Q0VDD7 K7EIN8 C19orf57 Uncharacterized protein C19orf57 1 0 ALEVAGPDGQAS(0.004)AIS(0.002)PAS(0.993)PR 85.287 0.0019182 11180000 1481.6 1372.1 1604.3 1643.6 1711 1853.2 1968 1566.7 2131.1 1718.1 TRUE FALSE FALSE 1364.329797 1490.69821 1663.756769 1636.799219 1690.597442 1468.82543 2023.216783 2044.379618 1897.323662 1777.803847 0.767424257 0.838505447 0.935849459 0.92068606 0.950947117 0.826202189 1.138042752 1.149946672 1.06722891 1 10.79588044 -4.751480848 24.88991859 0.890646349 1.143994903 0.52989449 0.084763072 106.9452915 267288.2874 0.012589353 0.045974952 1.77E-05 4.751480848 0.253348554 ALFAGDIEEMEERR ddPTM_HeLa_Curcumin_4h_R1 1 ALFAGDIEEMEERR 14 1 E7ES68;G5E9D5;Q9BQ52-3;Q9BQ52-4;Q9BQ52 E7ES68 ELAC2 Zinc phosphodiesterase ELAC protein 2 0 0 112.84 0.0037208 2103500 777.74 733.67 743.6 769.64 729.72 1014.6 591.08 708.61 1002.7 813.04 FALSE FALSE TRUE 716.1810583 797.0851656 771.1584701 766.4554336 721.0185656 804.1605231 607.664114 924.661927 892.7063186 841.2930795 0.851286045 0.947452422 0.916634748 0.911044501 0.857036131 0.95586252 0.722297769 1.099096081 1.061112162 1 9.716464666 -9.506450187 1.224067856 1.000643399 0.897280794 0.194736097 0.092740615 0.658051587 1.747013838 0.057587928 0.013565801 3.12E-10 9.506450187 -0.103362605 ALGALVDSCAPGLCPDWDSWDASKPVTNAR ddPTM_HeLa_Curcumin_4h_R1 1 ALGALVDSCAPGLCPDWDSWDASKPVTNAR 30 1 P21333-2;P21333;F8WE98;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 140.07 2.56E-13 0 752.21 627.09 653.9 474.28 718.57 1275.7 970.19 721.25 691.32 623.25 FALSE FALSE TRUE 692.6717848 681.2928653 678.1341092 472.317555 710.0015221 1011.10544 997.4109203 941.1558048 615.4839256 644.9078911 1.074063125 1.05641887 1.051520874 0.732379866 1.100934772 1.567829226 1.54659438 1.45936469 0.954374933 1 9.332949312 -5.317540007 4.92917902 1.017034796 1.527750391 0.853793606 0.100381334 0.055955211 2.924930711 0.014263297 0.033200846 4.81E-06 5.317540007 0.510715595 ALGDEDDLAKREDEFVDLGDV ddPTM_HeLa_Curcumin_4h_R1 1 ALGDEDDLAKREDEFVDLGDV 21 2 Q9C0I1-3;Q9C0I1-2;Q9C0I1 Q9C0I1-3 MTMR12 Myotubularin-related protein 12 0 0 74.726 0.0052337 6569800 2065.6 1366 1561.2 1692 1617.8 1972.8 1440.9 1525.2 2314.2 1838.5 FALSE FALSE TRUE 1902.10558 1484.070953 1619.059445 1684.998952 1598.508792 1563.619042 1481.327776 1990.226459 2060.33805 1902.387738 0.999851682 0.780109608 0.851067011 0.885728455 0.840264453 0.821924474 0.778667643 1.04617288 1.083027402 1 10.89359561 -7.281321325 24.06177054 0.999929974 0.853440604 0.504205545 0.075653404 285.5505502 345581.5745 0.011118253 0.012724568 5.23E-08 7.281321325 -0.14648937 ALGDLISATK ddPTM_HeLa_Curcumin_4h_R1 2 ALGDLISATK 10 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 ; ; 170.5 1.71E-12 3412800 3099.45 2888.26 3247.15 3109.3 2919.37 3873.16 3011.59 3137.11 3605.6 2630.41 FALSE FALSE TRUE 2854.125262 3137.908325 3367.492235 3096.43454 2884.558419 3069.822956 3096.08711 4093.600398 3210.074701 2721.816552 1.048610444 1.15287282 1.237222337 1.137635282 1.059791637 1.127858141 1.137507636 1.503995703 1.179386869 1 11.41035412 -1.112367785 0.920779276 1.058045699 200 0.607607857 0.082816481 346.1316244 0.827090366 0.013628576 144644.2055 0.077202651 1.112367785 198.9419543 ALGDS(ph)SPSQAMQEYIAVVK ddPTM_HeLa_Curcumin_4h_R1 2 ALGDSSPSQAMQEYIAVVK 19 0 A0A2R8Y544;Q9BR61 A0A2R8Y544 ACBD6 Acyl-CoA-binding domain-containing protein 6 1 0 ALGDS(0.56)S(0.436)PS(0.004)QAMQEYIAVVK;ALGDS(0.499)S(0.499)PS(0.002)QAMQEYIAVVK ; 156.06 1.48E-10 9509500 2690.9 2574.17 2223.08 2743.96 2204.97 3749.5 2581.22 2461.97 2989.8 2822 TRUE FALSE FALSE 2477.912426 2796.669785 2305.4693 2732.606221 2178.677173 2971.811434 2653.642086 3212.613319 2661.82642 2920.06429 0.848581462 0.957742538 0.789526898 0.935803444 0.746105892 1.017721235 0.908761528 1.100185818 0.91156432 1 11.51178442 -3.415195714 1.424157209 0.911019375 2.389353805 0.33350318 0.082704033 12.08081706 3.474766649 0.012737962 45.3656336 0.000384419 3.415195714 1.478334429 ALGQNPTNAEVLK ddPTM_HeLa_Curcumin_4h_R1 2 ALGQNPTNAEVLK 13 0 P60660-2;F8W1R7;G8JLA2;G3V1V0;P60660;J3KND3;B7Z6Z4;F8VPF3;F8W1I5;P14649 P60660-2 MYL6;MYL6B Myosin light polypeptide 6;Myosin light chain 6B 0 0 ; ; 270.61 1.09E-77 33348000 6693 4727 5639.4 4876.3 5205.5 7499.2 5697.4 5041.2 5861.4 5248.3 FALSE FALSE TRUE 6163.241988 5135.580817 5848.401125 4856.123163 5143.427812 5943.781387 5857.25371 6578.238673 5218.419084 5430.678034 1.134893645 0.945661073 1.076919141 0.894202001 0.947106011 1.094482374 1.078549248 1.211310748 0.960914834 1 12.40691662 -4.188463255 1.684148974 1.038402037 1.291924721 0.352263543 0.076562551 1.22631112 2.894644436 0.012065536 0.529255379 6.48E-05 4.188463255 0.253522684 ALGSPT(ph)KQLLPCEMACNEK ddPTM_HeLa_Curcumin_4h_R1 1 ALGSPTKQLLPCEMACNEK 19 1 Q9NR45;Q5TBR0 Q9NR45 NANS Sialic acid synthase 1 0 ALGS(0.055)PT(0.945)KQLLPCEMACNEK 108.25 0.00045775 22851000 1467.6 1007.3 1034.9 1277.3 707.39 1649.3 1177.1 868.94 2389.2 1766.7 TRUE FALSE FALSE 1351.437911 1094.366524 1073.254304 1272.014871 698.9548363 1307.216589 1210.126258 1133.875806 2127.110737 1828.092693 0.739261152 0.598638421 0.587089653 0.695815303 0.382341026 0.715071283 0.661961104 0.620250718 1.163568316 1 10.83612351 -8.307021521 0.607045328 0.992960742 0.600278466 0.733491713 0.107761518 0.27158513 0.217676411 0.048101611 0.02402572 4.93E-09 8.307021521 -0.392682276 APAPAAPRS(ph)PNLAGK ddPTM_HeLa_Curcumin_4h_R1 2 APAPAAPRSPNLAGK 15 1 Q9Y4B5 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 0 APAPAAPRS(1)PNLAGK;APAPAAPRS(1)PNLAGK ; 115.91 0.0018834 8580200 3186.3 2823.5 2682.8 2717.21 2130.47 2613.33 1886.49 1104.53 3982.3 2998.1 TRUE FALSE FALSE 2934.100993 3067.550759 2782.226928 2705.966905 2105.065537 2071.2959 1939.419832 1441.296112 3545.451653 3102.283752 0.945787435 0.988804057 0.896831867 0.872249969 0.678553513 0.6676681 0.62515875 0.464591968 1.142852149 1 11.59911493 -5.283896878 0.600318664 0.984451156 0.430419322 0.898428039 0.063452711 0.204272311 0.097341849 0.007820186 0.062681795 5.20E-06 5.283896878 -0.554031835 down RAVS(ph)PSNPK ddPTM_HeLa_Curcumin_4h_R1 4 RAVSPSNPK 9 1 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-3 MAP7 Ensconsin 1 0 RAVS(0.995)PS(0.005)NPK;RAVS(0.998)PS(0.002)NPK;RAVS(0.998)PS(0.002)NPK;RAVS(0.994)PS(0.006)NPK ;;; 120.77 0.0095073 179801000 17547.1 15725.6 14571.8 13765.5 13596.9 9213.7 6227.6 4561.53 16128.6 12624.9 TRUE FALSE FALSE 16158.22852 17084.85079 15111.84373 13708.54201 13434.76585 7302.67476 6402.329695 5952.319498 14359.33293 13063.61434 1.236888054 1.307819594 1.156788875 1.049368242 1.028411089 0.559008753 0.490088695 0.455641092 1.099185307 1 13.67326648 -5.274809907 2.267882803 1.13108676 0.465478313 0.923523355 0.08302308 0.079329784 0.788668314 0.016619737 0.04866663 5.31E-06 5.274809907 -0.665608447 down ALIAAQYSGAQVR ddPTM_HeLa_Curcumin_4h_R1 2 ALIAAQYSGAQVR 13 0 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 0 ; ; 194.17 2.25E-13 10248900 4322.7 2496.3 3542.4 2594.9 3583.9 4679.8 3467.1 3745.9 3102.9 3333.3 FALSE FALSE TRUE 3980.553734 2712.069049 3673.68446 2584.162991 3541.164333 3709.156728 3564.377495 4888.007666 2762.519633 3449.131927 1.154074074 0.786304817 1.065104072 0.749221267 1.026682774 1.075388476 1.03341292 1.417170398 0.800931855 1 11.7520176 -4.260876065 6.649183066 1.027832805 1.424356542 0.417135581 0.144155973 0.086120652 24.35881013 0.018217034 0.152187606 5.48E-05 4.260876065 0.396523736 ALIEMEK ddPTM_HeLa_Curcumin_4h_R1 1 ALIEMEK 7 0 Q15233;Q15233-2;H7C367;C9JYS8 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 0 104.21 0.0177 4219200 3158 2613.5 2877.8 2705.9 3270.6 3193.8 2747.9 2608.1 2831.6 2764.7 FALSE FALSE TRUE 2908.040968 2839.399294 2984.4538 2694.703703 3231.600231 2531.369878 2824.998678 3403.297684 2520.980564 2860.773119 1.016522753 0.992528654 1.043233306 0.941949463 1.129624789 0.884855168 0.987494835 1.189642639 0.881223522 1 11.48218937 -4.258338225 24.65478313 1.003810992 1.189642723 0.403355092 0.071384787 148.9813105 1184357.115 0.007232386 0.068627645 5.52E-05 4.258338225 0.185831731 ALIS(ph)FLEPK ddPTM_HeLa_Curcumin_4h_R1 1 ALISFLEPK 9 0 C9JSX6;A2RRC6;Q9C0A1-2;Q9C0A1 C9JSX6 ZFHX2 Zinc finger homeobox protein 2 1 0 ALIS(1)FLEPK 89.296 0.020353 195210000 5119.9 3452.1 4030.1 4327.5 4374 5701 4290.2 3945.5 4388.6 4339.3 TRUE FALSE FALSE 4714.654513 3750.484142 4179.459051 4309.593952 4321.842907 4518.548336 4410.571466 5148.464787 3907.18156 4490.090352 1.050013283 0.835280328 0.930818474 0.959801165 0.962529163 1.006337954 0.982290137 1.146628327 0.870178828 1 12.13252876 -4.258728923 24.10187612 0.993769629 1.146628417 0.281792835 0.070695209 144.2916857 1282940.924 0.009316924 0.085253083 5.51E-05 4.258728923 0.152858787 ALK(ac)EPPRDR ddPTM_HeLa_Curcumin_4h_R1 1 ALKEPPRDR 9 2 P30050;P30050-2 P30050 RPL12 60S ribosomal protein L12 0 1 ALK(1)EPPRDR 72.325 0.016334 4623200 1432.3 1944.9 1601.7 1283.8 2696.2 3658.1 2757.9 2371.8 3532.4 1812.4 FALSE TRUE FALSE 1318.931944 2113.00849 1661.060411 1278.487976 2664.049576 2899.368825 2835.279251 3094.950902 3144.904558 1875.380765 0.70328755 1.126709055 0.885719019 0.681721813 1.420537965 1.546016083 1.511841917 1.650305346 1.676941886 1 10.87296783 -5.654921906 5.234022943 0.870510481 1.550022838 0.398786237 0.285020721 0.062424594 2.653925696 0.021779724 0.044092096 2.21E-06 5.654921906 0.679512357 ALKCRQCSY(ph)T(ph)SPYFYALR ddPTM_HeLa_Curcumin_4h_R1 1 ALKCRQCSYTSPYFYALR 18 2 Q96JM2;Q96JM2-3;H3BLX4;Q96JM2-2 Q96JM2 ZNF462 Zinc finger protein 462 2 0 ALKCRQCS(0.001)Y(0.57)T(0.586)S(0.586)PY(0.098)FY(0.159)ALR 47.603 0.019882 12764000 1771.1 2001.4 2120.6 1660 2575.8 2235.6 1500.9 1350.4 2099.6 1992.4 TRUE FALSE FALSE 1630.915566 2174.392098 2199.191301 1653.13136 2545.085267 1771.91136 1543.011215 1762.130744 1869.279133 2061.635752 0.791078426 1.054692661 1.066721558 0.801854236 1.234498027 0.859468681 0.748440268 0.854724576 0.906697088 1 11.00957375 -5.005804546 24.9526443 0.939443447 0.802175389 0.207019126 0.129564878 373.4904118 1605594.631 0.019350417 0.055549176 9.87E-06 5.005804546 -0.137268058 ALLEAGALPNAPNSYGR ddPTM_HeLa_Curcumin_4h_R1 1 ALLEAGALPNAPNSYGR 17 0 J3QRG6;P42771;P42771-4;P42771-3 J3QRG6 CDKN2A Cyclin-dependent kinase inhibitor 2A 0 0 155.14 0.0030792 1526000 1105 532.8 549.12 731.82 774.42 1046.2 753.92 895.31 989.47 891.51 FALSE FALSE TRUE 1017.538084 578.8528579 569.4708703 728.7919227 765.1855473 829.2063269 775.0729661 1168.285897 880.9276165 922.4899061 1.103034383 0.627489639 0.617319351 0.790026989 0.829478504 0.898878482 0.84019669 1.266448435 0.954945535 1 9.849389315 -7.290218295 24.97103744 1.048655134 0.830208213 0.180701589 0.172411836 707.5247004 613906.8498 0.029514312 0.033754011 5.13E-08 7.290218295 -0.218446921 HMDPPPAPVQDRS(ph)PS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 HMDPPPAPVQDRSPSPR 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 HMDPPPAPVQDRS(1)PS(1)PR 69.255 0.01487 10369000 4754.1 4291.6 4374.3 3910 3765.5 2746.1 1434 1331.3 4335.1 3943.9 TRUE FALSE FALSE 4377.807968 4662.546781 4536.415406 3893.821456 3720.598872 2176.527905 1474.234181 1737.207241 3859.550376 4080.950231 1.072742308 1.142514982 1.111607628 0.954145784 0.911699154 0.533338507 0.361247772 0.425686946 0.945747965 1 11.9946894 -5.268137305 1.843647626 1.047104546 0.380639538 0.952941127 0.060155242 0.04834405 0.312551535 0.008645447 0.028202816 5.39E-06 5.268137305 -0.666465008 down ALLEVVQSGGK ddPTM_HeLa_Curcumin_4h_R1 1 ALLEVVQSGGK 11 0 O14818;O14818-2;Q8TAA3-2;Q8TAA3-5;Q8TAA3;A0A087WYS6 O14818 PSMA7;PSMA8 Proteasome subunit alpha type-7;Proteasome subunit alpha type-7-like 0 0 177.57 1.59E-11 2600200 2708.7 2502.9 1998.7 2389.8 2685.3 2747.4 2510.9 2259.6 2427.9 2293.8 FALSE FALSE TRUE 2494.303537 2719.239523 2072.77358 2379.911641 2653.279551 2177.55827 2581.349096 2948.541638 2161.565444 2373.509379 1.05089264 1.145662009 0.873294876 1.002697382 1.117871947 0.917442454 1.087566419 1.242270902 0.910704404 1 11.21280604 -4.347102984 3.513449956 1.02145932 1.251332388 0.412309143 0.084943981 0.169280974 3.402625049 0.00999727 0.087297644 4.50E-05 4.347102984 0.229873068 ALLFIPR ddPTM_HeLa_Curcumin_4h_R1 2 ALLFIPR 7 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 0 ; ; 117.54 0.0097862 7417700 2136.03 1721.47 1894.6 1644.28 1893.76 2237.2 2032.27 2151.4 1960.61 1806.34 FALSE FALSE TRUE 1966.960972 1870.266196 1964.815543 1637.476405 1871.178149 1773.179502 2089.290027 2807.351956 1745.535988 1869.110181 1.052351537 1.000618484 1.051203703 0.876072701 1.001106392 0.94867575 1.117799287 1.501972428 0.933886085 1 10.8681359 -4.28940795 2.932120374 1.009176735 1.569711579 0.882894438 0.056249598 0.082801262 1.04955583 0.007372459 0.105354991 5.14E-05 4.28940795 0.560534844 ALLFVPR ddPTM_HeLa_Curcumin_4h_R1 2 ALLFVPR 7 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 ; ; 172.78 1.29E-08 7938600 3048.6 1955.22 2091.55 2237.2 2472.1 2842.4 2363.5 2361.1 2506.8 2383.5 FALSE FALSE TRUE 2807.300093 2124.220505 2169.064683 2227.943059 2442.621822 2252.8542 2429.813449 3080.988521 2231.810312 2466.326448 1.138251628 0.86128927 0.87947185 0.903344754 0.990388691 0.913445259 0.985195391 1.249221701 0.904912776 1 11.26814805 -10.28919251 4.942862257 0.998526821 1.023485193 0 0.122209465 1.880956043 84.43910898 0.136091022 0.018397545 5.14E-11 10.28919251 0.024958372 ALLLLRRR ddPTM_HeLa_Curcumin_4h_R1 1 ALLLLRRR 8 2 A0A3B3IST2;O75344-3;O75344-2;O75344 A0A3B3IST2 FKBP6 Inactive peptidyl-prolyl cis-trans isomerase FKBP6 0 0 9.2405 0.020388 1939100 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 ALLPLELQDDGS(ph)DSRK ddPTM_HeLa_Curcumin_4h_R1 2 ALLPLELQDDGSDSRK 16 1 A0A1W2PPT2;Q15906;Q15906-2 A0A1W2PPT2 VPS72 Vacuolar protein sorting-associated protein 72 homolog 1 0 ALLPLELQDDGS(0.988)DS(0.012)RK;ALLPLELQDDGS(0.997)DS(0.003)RK ; 119.62 0.00045116 6190900 2922.1 2701.1 2597.7 2661.5 2769.9 3789.9 2852.2 2134.96 3040.5 2780.9 TRUE FALSE FALSE 2690.812702 2934.571048 2693.973047 2650.487418 2736.870752 3003.832019 2932.225056 2785.899476 2706.964757 2877.536068 0.935109982 1.01982077 0.936208264 0.921096159 0.951116054 1.04389031 1.019005492 0.968154494 0.940723137 1 11.4906183 -5.276371772 24.86133898 0.965265935 1.01121564 0.316915471 0.034165087 784.1821336 1305605.281 0.005366562 0.012051863 5.29E-06 5.276371772 0.045949706 ALLQSS(ph)ASR ddPTM_HeLa_Curcumin_4h_R1 1 ALLQSSASR 9 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 1 0 ALLQS(0.031)S(0.969)ASR 97.452 0.014624 10530000 3531.6 2625.6 3133.6 3492 3493.2 4907.5 4151 3152.2 2976.2 3330.9 TRUE FALSE FALSE 3252.070133 2852.545165 3249.733973 3477.551029 3451.545871 3889.629181 4267.465888 4113.291269 2649.718306 3446.648527 0.943545624 0.827628678 0.942867817 1.008965957 1.0014209 1.128525044 1.238149424 1.193417674 0.768781117 1 11.75097847 -5.18258684 1.712941894 0.959776437 1.222548334 0.701006006 0.07734278 0.127325794 0.700501317 0.008136264 0.030234711 6.57E-06 5.18258684 0.262771897 ALLS(ph)SPEGEEK ddPTM_HeLa_Curcumin_4h_R1 1 ALLSSPEGEEK 11 0 A0A499FJI4;O75592-2;O75592;H7C3U4 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 0 ALLS(0.918)S(0.082)PEGEEK 89.679 0.0178 6539700 5112 4325.3 5611.4 5673.9 5547.8 6685.8 4979.5 6243.1 5827.1 5377.7 TRUE FALSE FALSE 4707.379806 4699.159659 5819.36342 5650.422905 5481.646108 5299.089716 5119.211368 8146.59245 5187.881709 5564.574675 0.845955007 0.844477778 1.045787641 1.015427636 0.985097052 0.952290161 0.919964538 1.464009907 0.932305165 1 12.4420557 -4.260152115 24.90567115 0.939323409 1.464010085 0.852319369 0.064194141 34.12607784 660184.2334 0.010907848 0.090669655 5.49E-05 4.260152115 0.524686676 ALLTTGS(ph)LRVS(ph)EQTLQS(ph)AS(ph)SKVLK ddPTM_HeLa_Curcumin_4h_R1 1 ALLTTGSLRVSEQTLQSASSKVLK 24 2 J3KQV8;O43426;C9JFZ1;O43426-4;O43426-2 J3KQV8 SYNJ1 Synaptojanin-1 4 0 ALLT(0.124)T(0.425)GS(0.49)LRVS(0.879)EQT(0.096)LQS(0.574)AS(0.877)S(0.536)KVLK 42.536 0.0094382 0 309.86 285.27 402.61 342.05 380.39 403.11 248.09 220.86 310.85 214.27 TRUE FALSE FALSE 285.334254 309.9274677 417.5310808 340.6346877 375.8540977 319.500442 255.0507377 288.1991973 276.7505327 221.7158666 1.286936557 1.397858766 1.88318088 1.536356838 1.695206137 1.441035533 1.150349507 1.299858245 1.248221596 1 7.792568207 -7.943501193 1.008393089 1.061544492 1.490900684 0.319631986 0.203503271 0.319640425 0.68928043 0.057816507 0.047588428 1.14E-08 7.943501193 0.429356192 ALMDEVVK ddPTM_HeLa_Curcumin_4h_R1 4 ALMDEVVK 8 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 0 ;;; ;;; 143.85 0.00047201 35808000 15809.17 12750.19 14076.43 13290.1 14344.41 19360.2 14949.06 13919.93 15534.99 13800.26 FALSE FALSE TRUE 14557.85751 13852.25961 14598.11488 13235.10909 14173.36228 15344.67629 15368.49039 18164.05258 13830.84046 14279.81801 1.019470802 0.970058554 1.022289981 0.92684018 0.992545022 1.074570858 1.076238533 1.272008689 0.968558595 1 13.80168997 -3.834456399 1.105533899 1.001185628 1.680877718 0.863968297 0.033626814 0.955723805 0.493815573 0.004823998 0.949692529 0.000146401 3.834456399 0.67969209 ALMDEVVK(ac)ATSR ddPTM_HeLa_Curcumin_4h_R1 1 ALMDEVVKATSR 12 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 1 ALMDEVVK(1)ATSR 97.472 0.011955 388680 0 0 0 0 78.626 0 0 0 147.31 0 FALSE TRUE FALSE 0 0 0 0 77.6884363 0 0 0 131.1504616 0 0 ALNHEIEELEK ddPTM_HeLa_Curcumin_4h_R1 2 ALNHEIEELEK 11 0 Q5T821;O95347-2;O95347 Q5T821 SMC2 Structural maintenance of chromosomes protein 2 0 0 ; ; 164.9 0.00021715 6704900 9140.5 7194.6 7382.6 8456.4 7365.1 9211.2 6620.3 6008.9 8816.9 8128.6 FALSE FALSE TRUE 8417.01978 7816.469165 7656.20565 8421.409657 7277.275993 7300.693288 6806.0478 7840.985948 7849.708129 8411.068245 1.000707584 0.929307543 0.91025366 1.0012295 0.865202348 0.867986453 0.809177574 0.932222367 0.933259355 1 13.03807333 -6.232070216 0.622108397 1.002770747 0.855128345 0.362562555 0.049064104 0.392146436 0.291007339 0.009648172 0.026477129 5.86E-07 6.232070216 -0.147642402 SES(ph)LDPDSSMDTTLILK ddPTM_HeLa_Curcumin_4h_R1 2 SESLDPDSSMDTTLILK 17 0 H0Y2V6;Q5SW79;Q5SW79-3;Q5SW79-2 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 0 S(0.017)ES(0.464)LDPDS(0.243)S(0.243)MDT(0.027)T(0.006)LILK;S(0.01)ES(0.426)LDPDS(0.038)S(0.233)MDT(0.246)T(0.047)LILK ; 127.05 0.0004078 69700000 7681.7 5048 6457.3 6470.5 6734.3 16457.3 23538.2 26543.7 6964.9 6131.8 TRUE FALSE FALSE 7073.685339 5484.326627 6696.613218 6443.726785 6653.997871 13043.87047 24198.61854 34636.75194 6200.867895 6344.879594 1.114865181 0.864370481 1.055435823 1.015579049 1.048719329 2.05581056 3.813881443 5.459008548 0.97730269 1 12.63137707 -4.604808796 1.471790774 1.026599458 5.936011683 0.996200749 0.091192805 0.028857648 0.087464725 0.015023341 0.171126236 2.48E-05 4.604808796 4.909412226 up ALPDSQQVPSS(ph)PASK ddPTM_HeLa_Curcumin_4h_R1 2 ALPDSQQVPSSPASK 15 0 O14924-7;O14924-6;O14924-2;O14924-3;O14924-5;O14924-4;O14924 O14924-7 RGS12 Regulator of G-protein signaling 12 1 0 ALPDSQQVPS(0.053)S(0.947)PASK;ALPDS(0.035)QQVPS(0.274)S(0.683)PAS(0.008)K ; 151.22 0.00043224 6508300 4432 3780.2 3557.2 4109.8 4369.9 4926.1 3310.04 1484.76 4674.4 3499.4 TRUE FALSE FALSE 4081.202523 4106.943644 3689.032961 4092.794737 4317.791797 3904.371331 3402.910814 1937.456489 4161.630015 3621.00389 1.12709145 1.134200285 1.018787351 1.130292831 1.192429483 1.078256597 0.939769997 0.535060593 1.149302829 1 11.82217401 -4.27581204 2.334694706 1.078888036 0.413461153 0.889849734 0.060054274 0.152386234 0.999008196 0.00975869 0.202780951 5.30E-05 4.27581204 -0.665426882 ALPGQLKPFETLLSQNQGGK ddPTM_HeLa_Curcumin_4h_R1 2 ALPGQLKPFETLLSQNQGGK 20 1 P09211;A0A087X243 P09211 GSTP1 Glutathione S-transferase P 0 0 ; ; 105.28 0.00029694 7609580 1017.84 786.35 852.6 862.5 708.42 906.65 824.4 822.72 790.9 752.92 FALSE FALSE TRUE 937.27689 854.3185901 884.198106 858.9312035 699.9725542 718.6005699 847.5304452 1073.563541 704.1402487 779.083914 1.203049984 1.096568129 1.134920244 1.10248869 0.898455919 0.922366073 1.087855146 1.377981911 0.9038054 1 9.605634917 ALPNNT(ph)SSSPQPK ddPTM_HeLa_Curcumin_4h_R1 1 ALPNNTSSSPQPK 13 0 A0A087WXZ1;A0A087WT22;E7ESS1;A0A087X1Q1;J3KP33;A0A087WZU8;A0A0U1RQC9;P04637-8;P04637-9;P04637-7;P04637-5;P04637-6;P04637-2;P04637-3;P04637-4;P04637 A0A087WXZ1 TP53 Cellular tumor antigen p53 1 0 ALPNNT(0.95)S(0.041)S(0.005)S(0.005)PQPK 149.57 0.0016584 8670100 2938.3 2261.5 2503.1 2399 2139.5 4142.3 3524.9 1077.4 3196.4 2404.3 TRUE FALSE FALSE 2705.730455 2456.973983 2595.867088 2389.073574 2113.98786 3283.140287 3623.799207 1405.8943 2845.762917 2487.849246 1.08757814 0.987589576 1.043418162 0.960296761 0.849725064 1.319670109 1.456599194 0.565104297 1.143864694 1 11.28068335 -9.622128144 1.425148778 0.999910507 1.05337671 0 0.23401335 3.063343934 11.14436964 0.155780606 0.035389149 2.39E-10 9.622128144 0.053466203 ALPNNTSS(ph)SPQPK ddPTM_HeLa_Curcumin_4h_R1 1 ALPNNTSSSPQPK 13 0 A0A087WXZ1;A0A087WT22;E7ESS1;A0A087X1Q1;J3KP33;A0A087WZU8;A0A0U1RQC9;P04637-8;P04637-9;P04637-7;P04637-5;P04637-6;P04637-2;P04637-3;P04637-4;P04637 A0A087WXZ1 TP53 Cellular tumor antigen p53 1 0 ALPNNT(0.037)S(0.125)S(0.419)S(0.419)PQPK 124.48 0.0020931 6842100 2621.2 1852.4 2089.6 2122.3 2210 3004 3047.7 868.91 2531.4 2089.8 TRUE FALSE FALSE 2413.729254 2012.513202 2167.042414 2113.518485 2183.647193 2380.936538 3133.21026 1133.836659 2253.711753 2162.420394 1.116216468 0.930676203 1.002137429 0.977385568 1.009816222 1.101051648 1.448936695 0.524336832 1.042217211 1 11.07843131 -4.228021189 24.15192907 1.058716239 0.524335164 0.584359164 0.137728616 5783.656033 4179842.055 0.018342385 4.183627069 5.92E-05 4.228021189 -0.534381075 ALPQT(ph)PRPR ddPTM_HeLa_Curcumin_4h_R1 2 ALPQTPRPR 9 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 ALPQT(1)PRPR;ALPQT(1)PRPR ; 101.39 0.010081 86663000 1767.9 1811.98 1576.13 1369.86 1811.46 2001.29 1774.16 1240.78 1992.93 1645.15 TRUE FALSE FALSE 1627.96885 1968.599477 1634.542764 1364.191882 1789.859523 1586.199895 1823.938155 1619.08811 1774.310565 1702.31884 0.956324286 1.156422305 0.960186027 0.801372722 1.051424375 0.931787781 1.071443323 0.951107438 1.042290388 1 10.73328556 -4.599568335 0.002274388 1.503057597 0.456178448 0 0.091356364 1572895.171 642.0836541 145676.2386 149890.9157 2.51E-05 4.599568335 -1.046879149 ALPQTPRPR ddPTM_HeLa_Curcumin_4h_R1 2 ALPQTPRPR 9 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 0 ; ; 125.16 0.0042244 10596600 731.01 677.25 576.85 751.64 633.22 680.13 859.56 601.61 752.94 588.15 FALSE FALSE TRUE 673.1497871 735.7884722 598.2285684 748.5299128 625.6692651 539.0633714 883.6769402 785.0381195 670.3443658 608.5881687 1.106084248 1.209008834 0.982977651 1.229944898 1.028066757 0.885760518 1.452011369 1.289933258 1.101474528 1 9.249322477 -4.750677455 24.99996975 1.060121257 1.370972402 0.573415667 0.104383883 106.4817671 247352.3187 0.013963537 0.051181945 1.78E-05 4.750677455 0.310851145 AS(ph)PSPQPSSQPLQIHR ddPTM_HeLa_Curcumin_4h_R1 2 ASPSPQPSSQPLQIHR 16 0 B5MBZ0;Q9HC35 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 0 AS(0.747)PS(0.252)PQPSSQPLQIHR;AS(0.5)PS(0.5)PQPS(0.001)SQPLQIHR ; 103.73 0.00099331 86892000 4554.8 3729.3 3856.8 3546.3 3239.6 2511.2 1137.12 913.71 4712.3 3871.8 TRUE FALSE FALSE 4194.282774 4051.644075 3999.736401 3531.62635 3200.969886 1990.348813 1169.024527 1192.295973 4195.37248 4006.344762 1.046910095 1.011306893 0.998350526 0.881508347 0.798975145 0.496799185 0.291793292 0.29760194 1.04718209 1 11.96807086 -5.26194328 1.133628439 1.021010816 0.237120257 0.990266909 0.028824421 0.036899079 0.082369433 0.004646032 0.022211209 5.47E-06 5.26194328 -0.783890559 down ALPSLNTGSS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 ALPSLNTGSSSPR 13 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 0 ALPSLNT(0.017)GS(0.12)S(0.431)S(0.431)PR 114.21 0.0031478 343820000 3198.7 2383.9 3054 3085.3 2769.4 3231.3 2319.3 1873.6 2876.5 2651.4 TRUE FALSE FALSE 2945.51952 2589.953694 3167.183927 3072.533846 2736.376714 2561.091956 2384.373316 2444.852015 2560.955147 2743.535953 1.073621622 0.944020322 1.154416775 1.119917471 0.997390507 0.933500417 0.869087687 0.891131757 0.933450551 1 11.42182077 -5.2192253 2.497661891 1.043404742 0.883490142 0.472165379 0.066559181 0.164830718 1.999922406 0.008737832 0.025781801 6.04E-06 5.2192253 -0.1599146 ALPSLNTGSSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 ALPSLNTGSSSPR 13 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 0 ALPSLNT(0.01)GS(0.01)S(0.038)S(0.941)PR;ALPSLNTGS(0.061)S(0.204)S(0.734)PR ; 125.84 0.0019681 417473000 5423.4 4606.6 4886.3 4770.7 5042.1 5852.4 4161.8 3355.7 5777.5 4802.2 TRUE FALSE FALSE 4994.132167 5004.773977 5067.390576 4750.960107 4981.976251 4638.54627 4278.568907 4378.837482 5143.722705 4969.076093 1.005042401 1.007184008 1.019785264 0.956105324 1.002596088 0.93348264 0.86103912 0.881217635 1.035146697 1 12.27876192 -5.031154799 2.275046538 1.001073603 0.868839818 0.875418336 0.020145679 0.059200989 0.594504399 0.002314571 0.00845002 9.31E-06 5.031154799 -0.132233785 ALPTSKPEGSLHS(ph)SPVGPSSSK ddPTM_HeLa_Curcumin_4h_R1 1 ALPTSKPEGSLHSSPVGPSSSK 22 1 M0QY97;Q9UPT8 M0QY97 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 0 ALPTSKPEGSLHS(0.925)S(0.065)PVGPS(0.003)S(0.005)S(0.001)K 93.229 0.00032402 0 2466.8 2124.8 1843.7 1837.6 3352.8 6095.6 2658.2 1549.1 3380 1857 TRUE FALSE FALSE 2271.550177 2308.458244 1912.029144 1829.996498 3312.82005 4831.303848 2732.781938 2021.413459 3009.222456 1921.530612 1.182156643 1.201364282 0.995055261 0.952363958 1.724052705 2.514299704 1.422190165 1.051980877 1.566054914 1 10.90804024 -5.754507734 24.84879687 1.081699777 1.719575897 0.304143592 0.381529612 110.246486 395211.2632 0.051145165 0.100511693 1.76E-06 5.754507734 0.63787612 ALQEGEGDLSIS(ph)ADR ddPTM_HeLa_Curcumin_4h_R1 1 ALQEGEGDLSISADR 15 0 B4DKY1;P49589-2;P49589;P49589-3 B4DKY1 CARS "Cysteine--tRNA ligase, cytoplasmic" 1 0 ALQEGEGDLSIS(1)ADR 98.227 0.0045693 2727400 1692.9 1944.5 1992.9 2052.2 2062.5 1664.7 1381 1171.4 2221.4 1663.1 TRUE FALSE FALSE 1558.905179 2112.573915 2066.758627 2043.70854 2037.906035 1319.422455 1419.747143 1528.554468 1977.717978 1720.892601 0.905870115 1.227603579 1.200980599 1.187586337 1.184214537 0.766708192 0.825006245 0.888233505 1.149239631 1 10.74894135 -5.242257964 24.72765764 1.025442076 0.826484995 0.422970787 0.126823283 760.5183428 980417.8432 0.021238132 0.054054098 5.72E-06 5.242257964 -0.198957082 ALQESATGQPEPT(ph)SSPDNKPFK ddPTM_HeLa_Curcumin_4h_R1 2 ALQESATGQPEPTSSPDNKPFK 22 1 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 0 ALQESATGQPEPT(0.333)S(0.333)S(0.333)PDNKPFK;ALQESATGQPEPT(0.408)S(0.328)S(0.264)PDNKPFK ; 75.226 0.0012393 32668000 4334.2 2716.4 3403.4 4022.2 4155.9 4523.7 3198.1 1568.25 4202.3 4128.1 TRUE FALSE FALSE 3991.143497 2951.193512 3529.532998 4005.557202 4106.343607 3585.433627 3287.830079 2046.402206 3741.318204 4271.551168 0.934354603 0.690895039 0.826288357 0.937728953 0.961323755 0.839375086 0.769704014 0.479077067 0.875868755 1 12.06054435 -3.966763202 1.053653032 0.934454795 4.73E-13 0.62266379 0.090479953 1.421186145 0.822991434 0.015425064 1.719255002 0.000107954 3.966763202 -0.934454795 ALQESATGQPEPTS(ph)SPDNKPFK ddPTM_HeLa_Curcumin_4h_R1 1 ALQESATGQPEPTSSPDNKPFK 22 1 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 0 ALQESATGQPEPT(0.047)S(0.476)S(0.476)PDNKPFK 70.501 0.001033 25224000 2806.5 1524.8 2351.2 2513.6 2293.4 2682 1997.1 952.24 2766.5 2567 TRUE FALSE FALSE 2584.362564 1656.596918 2438.33754 2503.199389 2266.052703 2125.722968 2053.133251 1242.573592 2463.021871 2656.203059 0.972953689 0.623671038 0.917978591 0.942397601 0.85311727 0.800286319 0.772957942 0.467800678 0.927271679 1 11.37514973 -3.415274566 0.33062449 0.986875925 7.62E-31 0.498093353 0.113696463 6.439764366 0.326159828 0.039854835 2.847187584 0.000384349 3.415274566 -0.986875925 ALQEVGSGGTLGLSS(ph)PKS ddPTM_HeLa_Curcumin_4h_R1 2 ALQEVGSGGTLGLSSPKS 18 1 A0A0M3HER3 A0A0M3HER3 1 0 ALQEVGSGGTLGLS(0.029)S(0.969)PKS(0.002);ALQEVGSGGTLGLS(0.046)S(0.953)PKS(0.001) ; 159.95 5.58E-05 44321000 4081.1 3504.5 4032.6 3877.9 3596.7 4693.7 3138.8 2641 5000.5 3232 TRUE FALSE FALSE 3758.076629 3807.413364 4182.051703 3861.854277 3553.811702 3720.173711 3226.86628 3446.228742 4451.957661 3344.311759 1.123721979 1.138474412 1.250496964 1.154753072 1.062643664 1.112388431 0.964882018 1.030474726 1.331202944 1 11.70749363 -4.765068394 24.98318274 1.089100598 0.997678365 0.07957196 0.101951663 118.4039161 815155.4725 0.011863417 0.037740895 1.72E-05 4.765068394 -0.091422233 ALQLEEER ddPTM_HeLa_Curcumin_4h_R1 1 ALQLEEER 8 0 E7EQR4;P15311 E7EQR4 EZR Ezrin 0 0 124.08 0.0022838 11531000 3945 2335.3 2980.7 3159.3 2930.7 4028.6 3490.6 3285.2 4153.2 2574.4 FALSE FALSE TRUE 3632.749087 2537.152926 3091.167364 3146.227654 2895.753317 3193.022948 3588.536842 4286.842357 3697.604351 2663.860208 1.363716112 0.95243471 1.160409001 1.181078363 1.087051531 1.198645086 1.347119053 1.609259504 1.388062459 1 11.37930266 -4.375640658 1.747076982 1.153013351 1.702817249 0.528585827 0.130091307 0.464065696 1.660266769 0.020649352 0.390645696 4.21E-05 4.375640658 0.549803898 ALQT(ph)SPQPPEGPGLPR ddPTM_HeLa_Curcumin_4h_R1 1 ALQTSPQPPEGPGLPR 16 0 F8W9A8;B7WPL9;Q6PFW1-7;Q6PFW1-4;Q6PFW1-3;Q6PFW1-2;Q6PFW1;A0A2R8YGT1;Q6PFW1-5;H7C398 F8W9A8 PPIP5K1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 1 0 ALQT(0.932)S(0.068)PQPPEGPGLPR 121.95 0.0023714 7423300 2682.3 2081 2353.6 2690.3 1923 1273.4 1298.7 1012.4 2892.6 2281.9 TRUE FALSE FALSE 2469.993125 2260.872367 2440.826486 2679.168251 1900.069481 1009.282486 1335.138027 1321.076099 2575.289017 2361.195855 1.04607719 0.957511577 1.033724704 1.134665829 0.804706427 0.427445476 0.565449928 0.559494502 1.090671497 1 11.205302 -5.489373335 3.978365441 1.02438776 0.52662803 0.937529591 0.06069751 0.034877958 1.193966715 0.008102678 0.018217654 3.24E-06 5.489373335 -0.49775973 ALRPGDLPPS(ph)PDDVKR ddPTM_HeLa_Curcumin_4h_R1 1 ALRPGDLPPSPDDVKR 16 2 O75382-3;O75382-2;O75382;A0A1W2PPI7;O75382-4 O75382-3 TRIM3 Tripartite motif-containing protein 3 1 0 ALRPGDLPPS(1)PDDVKR 99.343 0.0022234 7125900 2217.6 1841.8 2186.6 2155.2 2421.6 2804.1 1965.4 1355.8 2810.2 2058.9 TRUE FALSE FALSE 2042.07462 2000.996985 2267.63732 2146.282353 2392.724002 2222.498051 2020.543834 1769.177179 2501.928091 2130.446622 0.958519495 0.939238263 1.064395276 1.007433057 1.123109106 1.043207574 0.948413264 0.830425489 1.174367884 1 11.05694019 -4.345667043 3.219847345 0.998511106 0.820433612 0.335230488 0.076339032 0.202003351 3.332861781 0.008025718 0.078565259 4.51E-05 4.345667043 -0.178077494 ALS(ph)ASHTDLAH ddPTM_HeLa_Curcumin_4h_R1 2 ALSASHTDLAH 11 0 Q07866-6;Q07866-4;Q07866-7;H0YG16;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 0 ALS(0.764)AS(0.185)HT(0.052)DLAH;ALS(0.475)AS(0.05)HT(0.475)DLAH ; 102.06 0.0085978 192075600 9302.5 7264.8 7429.9 8285.5 9094.3 12770.2 8841.1 7625.5 9471.7 8601.5 TRUE FALSE FALSE 8566.197309 7892.736941 7705.25863 8251.216796 8985.856412 10121.51657 9089.157471 9950.479847 8432.678207 8900.401485 0.962450663 0.886784372 0.865720343 0.92706119 1.009601244 1.137197753 1.021207581 1.117981011 0.947449193 1 13.1196547 -5.48858895 5.511913511 0.960880414 1.084276739 0.648192582 0.050354879 0.125877889 10.47670117 0.008317508 0.018369202 3.25E-06 5.48858895 0.123396326 ALS(ph)DREEEEEDDEEEEEEVEAAAQR ddPTM_HeLa_Curcumin_4h_R1 1 ALSDREEEEEDDEEEEEEVEAAAQR 25 1 Q8N3E9 Q8N3E9 PLCD3 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3" 1 0 ALS(1)DREEEEEDDEEEEEEVEAAAQR 69.27 0.00035444 8819000 1003.8 916.26 849.33 922.65 1054.5 1371.2 762.14 373.62 1222.8 1046.5 TRUE FALSE FALSE 924.3481708 995.4574316 880.8069169 918.8323188 1041.925776 1086.797663 783.5235972 487.5350181 1088.661899 1082.865797 0.853612861 0.919280519 0.813403581 0.848519107 0.962192895 1.003630982 0.723564822 0.45022663 1.005352558 1 10.08063874 -4.429867215 2.873289791 0.920234925 0.438521262 0.824893413 0.068010144 0.102731022 1.39258717 0.01063979 0.093379774 3.72E-05 4.429867215 -0.481713663 ALS(ph)DVTDEEEVQVDPR ddPTM_HeLa_Curcumin_4h_R1 2 ALSDVTDEEEVQVDPR 16 0 Q16659 Q16659 MAPK6 Mitogen-activated protein kinase 6 1 0 ALS(0.898)DVT(0.102)DEEEVQVDPR;ALS(0.922)DVT(0.078)DEEEVQVDPR ; 219.53 2.20E-15 7404600 1241.68 1015.18 938.63 1134.48 1169.45 1412.44 1330.72 767.9 1289.58 995.92 TRUE FALSE FALSE 1143.399718 1102.927636 973.4164535 1129.785822 1155.505073 1119.484023 1368.056422 1002.029175 1148.1163 1030.528146 1.109527889 1.070254743 0.944580172 1.096317288 1.121274637 1.086320667 1.32752941 0.972345277 1.114104748 1 10.00916819 -5.90450581 3.529661416 1.046601413 1.138789297 0.128964249 0.094054508 0.311366858 7.628197648 0.01334816 0.025189621 1.25E-06 5.90450581 0.092187884 ALS(ph)EGEEITAAPER ddPTM_HeLa_Curcumin_4h_R1 1 ALSEGEEITAAPER 14 0 O43822-2;O43822-3;O43822;O43822-4 O43822-2 C21orf2 Protein C21orf2 1 0 ALS(1)EGEEITAAPER 130.47 0.0010767 3615700 707.68 410.99 434.13 539.72 415.36 546.9 514.26 535.35 599.29 701.58 TRUE FALSE FALSE 651.6663813 446.5141443 450.2192397 537.4867816 410.4071033 433.4667752 528.6887515 698.5757506 533.5493863 725.9598528 0.897661735 0.615067269 0.620170989 0.740380862 0.565330303 0.597094693 0.728261693 0.962278765 0.734957153 1 9.503745956 -7.408796879 3.730316437 0.957149589 0.682563648 0.255150448 0.128750961 0.129075083 3.11904093 0.019675432 0.02219088 3.90E-08 7.408796879 -0.274585942 ALS(ph)GHSAADR ddPTM_HeLa_Curcumin_4h_R1 1 ALSGHSAADR 10 0 A0A0U1RQE4 A0A0U1RQE4 1 0 ALS(0.999)GHS(0.001)AADR 71.268 0.020144 9315600 4369.9 3832 4054.4 3528.4 4296.2 3835.6 2770.4 1197 3025.5 3559.9 TRUE FALSE FALSE 4024.017804 4163.221005 4204.659631 3513.800416 4244.970621 3040.053324 2848.129968 1561.95979 2693.610219 3683.60626 1.092412576 1.1302025 1.141451972 0.953902282 1.152395322 0.825292691 0.773190663 0.424030062 0.731242709 1 11.84690314 -4.302075096 1.067549229 1.059120721 0.146647164 0.670806219 0.12785694 0.403971369 0.377744691 0.011458693 0.409331022 4.99E-05 4.302075096 -0.912473556 ALS(ph)ISPLSDASLDLQR ddPTM_HeLa_Curcumin_4h_R1 2 ALSISPLSDASLDLQR 16 0 P10070 P10070 GLI2 Zinc finger protein GLI2 1 0 ALS(0.92)IS(0.08)PLSDASLDLQR;ALS(0.935)IS(0.065)PLSDASLDLQR ; 241.3 4.10E-30 7582400 1910.56 1290.95 1434.63 1474.39 1592.86 2436.2 2045.08 2671.6 1801.72 1760.68 TRUE FALSE FALSE 1759.33716 1402.533966 1487.79865 1468.289365 1573.866185 1930.904658 2102.459441 3486.158541 1604.075824 1821.863499 0.965680009 0.769834824 0.816635632 0.805927209 0.863877116 1.059851443 1.154015897 1.91351248 0.88045884 1 10.83119916 -4.068124169 1.586167455 0.935728242 2.681843021 0.91935295 0.090465264 0.414444851 0.667222177 0.015445612 1.287009141 8.55E-05 4.068124169 1.746114779 DS(ph)HSPDLQLPTPEVIPSSGSK ddPTM_HeLa_Curcumin_4h_R1 1 DSHSPDLQLPTPEVIPSSGSK 21 0 H3BPE1;H3BQK9;H0Y6T5;H0Y4F5 H3BPE1 MACF1 1 0 DS(0.582)HS(0.418)PDLQLPTPEVIPSSGSK 116.35 0.00016413 0 3664.7 2910.2 2875.1 3038.9 2711.2 1293.1 1114.6 285.64 3231.1 2388.4 TRUE FALSE FALSE 3374.635128 3161.74472 2981.653735 3026.325837 2678.870711 1024.896484 1145.872676 372.7303211 2876.656414 2471.396722 1.365476897 1.27933516 1.206465036 1.224540686 1.083950095 0.414703343 0.463653879 0.15081768 1.163980023 1 11.2711109 -5.261004167 2.874001438 1.19215569 0.321319627 0.923167666 0.112527596 0.069651565 1.149722201 0.022338436 0.060878097 5.48E-06 5.261004167 -0.870836063 down ALS(ph)PGLEESGLGLLAR ddPTM_HeLa_Curcumin_4h_R1 2 ALSPGLEESGLGLLAR 16 0 H9KVB4;O15417-2;O15417 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 0 ALS(1)PGLEESGLGLLAR;ALS(1)PGLEESGLGLLAR ; 236.12 1.29E-22 60899000 1985.5 2049.82 1908.47 1734.41 1893.9 1735.84 1624.97 505.99 1567.56 1810.42 TRUE FALSE FALSE 1828.34558 2226.997307 1979.199577 1727.233471 1871.316479 1375.807217 1670.562285 660.2640217 1395.60259 1873.33196 0.9759859 1.188789469 1.056513004 0.922011425 0.99892412 0.734417202 0.89175988 0.352454362 0.744984135 1 10.87139086 -4.104888131 0.971901192 1.004482308 1.36E-16 0.644717528 0.131059342 0.885866613 0.523273989 0.014899177 0.997680509 7.85E-05 4.104888131 -1.004482308 ALS(ph)PLPTR ddPTM_HeLa_Curcumin_4h_R1 1 ALSPLPTR 8 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 0 ALS(0.991)PLPT(0.009)R 94.409 0.018325 9252600 5070.4 3370.4 4602.4 5139.2 3540.2 2772.2 1547.4 1994.3 4349.5 3040.8 TRUE FALSE FALSE 4669.07249 3661.722358 4772.968993 5117.935352 3497.985427 2197.214471 1590.815879 2602.352889 3872.370732 3146.467574 1.483909298 1.163756585 1.516929344 1.626565421 1.111718251 0.698311494 0.505587883 0.827071256 1.23070416 1 11.61951736 -5.327043131 3.697275407 1.279611413 0.653051513 0.695097386 0.192570314 0.128172625 3.463529477 0.034853077 0.084770077 4.71E-06 5.327043131 -0.6265599 ALS(ph)PVIPLIPR ddPTM_HeLa_Curcumin_4h_R1 2 ALSPVIPLIPR 11 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 0 ALS(1)PVIPLIPR;ALS(1)PVIPLIPR ; 172.61 0.00022526 168910000 5476.5 3730.6 4567.5 4716.1 4792.3 4871.8 3650.5 2048.52 4269.6 4506.3 TRUE FALSE FALSE 5043.029246 4053.056441 4736.775568 4696.586028 4735.154952 3861.333763 3752.923205 2673.104318 3801.235562 4662.89359 1.081523554 0.869214869 1.015844663 1.00722565 1.015497107 0.828098195 0.804848563 0.573271568 0.815209588 1 12.18700979 -3.819936592 0.669478828 1.027875697 5.36E-13 0.618695908 0.089549694 1.378426163 0.285488693 0.010640345 1.234692082 0.000151378 3.819936592 -1.027875697 ALS(ph)PVTSR ddPTM_HeLa_Curcumin_4h_R1 2 ALSPVTSR 8 0 Q96L91-4;Q96L91-3;Q96L91-5;Q96L91-2;Q96L91;A0A0A0MR72;A0A0A0MR80 Q96L91-4 EP400 E1A-binding protein p400 1 0 ALS(0.995)PVT(0.005)SR;ALS(0.993)PVT(0.007)SR ; 108.43 0.011753 148628000 14781.9 12716.8 13825.5 14501.7 13470.7 14589.5 10420.9 8837.8 15683.5 12827.4 TRUE FALSE FALSE 13611.89702 13815.98353 14337.88519 14441.69581 13310.0707 11563.47324 10713.28241 11532.40454 13963.05929 13273.1512 1.02552113 1.04089702 1.080217123 1.088038221 1.002781518 0.871192761 0.807139333 0.868852043 1.051977717 1 13.6962233 -5.240408156 3.509304108 1.025843229 0.838786624 0.879962113 0.032415439 0.067066039 1.759360358 0.005230902 0.01382818 5.75E-06 5.240408156 -0.187056605 ALS(ph)SAGPIPIRPPIVPVK ddPTM_HeLa_Curcumin_4h_R1 2 ALSSAGPIPIRPPIVPVK 18 1 Q765P7;A0A087WXN9 Q765P7 MTSS1L MTSS1-like protein 1 0 ALS(0.949)S(0.051)AGPIPIRPPIVPVK;ALS(0.5)S(0.5)AGPIPIRPPIVPVK ; 98.804 0.00071793 147184000 4161.7 3795.4 4386.1 4666.4 4144.8 4821.3 3157.7 4403 4307.8 3729.1 TRUE FALSE FALSE 3832.297054 4123.457464 4548.652724 4647.091673 4095.375967 3821.308033 3246.296563 5745.454431 3835.245118 3858.685947 0.993161171 1.068617016 1.178808741 1.204319744 1.06133954 0.990313305 0.841295873 1.488966583 0.993925178 1 11.91389391 -7.12082388 3.95238821 0.996876808 1.109650155 0.117336458 0.157006511 0.413140216 11.2561132 0.024893587 0.030843115 7.57E-08 7.12082388 0.112773348 QPS(ph)EEEIIK ddPTM_HeLa_Curcumin_4h_R1 3 QPSEEEIIK 9 0 B1AKZ5;Q15121;Q15121-2 B1AKZ5 PEA15 Astrocytic phosphoprotein PEA-15 1 0 QPS(1)EEEIIK;QPS(1)EEEIIK;QPS(1)EEEIIK ;; 118.76 0.0065555 1364200000 8698.3 6460.8 7013.1 7021.9 8170.1 25275.5 28804.4 33888.8 8001.6 5876.6 TRUE FALSE FALSE 8009.820377 7019.242763 7273.011655 6992.845238 8072.676894 20033.07639 29612.57394 44221.33912 7123.844499 6080.811413 1.317228875 1.154326666 1.196059401 1.149985547 1.327565738 3.294474212 4.869839226 7.272276036 1.171528603 1 12.57004813 -4.589788701 1.140624366 1.13195892 8.39074777 0.990459726 0.197747792 0.065819744 0.100345054 0.031990724 0.493394782 2.57E-05 4.589788701 7.25878885 up ALS(ph)SDSILSPAPDAR ddPTM_HeLa_Curcumin_4h_R1 7 ALSSDSILSPAPDAR 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 ALS(0.36)S(0.36)DS(0.279)ILSPAPDAR;ALS(0.947)S(0.049)DS(0.004)ILSPAPDAR;ALS(0.476)S(0.089)DS(0.434)ILS(0.002)PAPDAR;ALS(0.935)S(0.064)DS(0.001)ILSPAPDAR;ALS(0.893)S(0.038)DS(0.069)ILSPAPDAR;ALS(0.745)S(0.152)DS(0.069)ILS(0.033)PAPDAR;ALS(0.705)S(0.18)DS(0.113)ILS(0.002)PAPDAR ;;;;;; 178.67 6.81E-05 2181517100 7965.15 7623.33 7956.82 7325.78 7466.64 11741.3 8441.16 9246.09 10023.1 8484.8 TRUE FALSE FALSE 7334.699973 8282.256676 8251.706749 7295.467863 7377.605195 9306.022028 8677.996231 12065.18028 8923.591007 8779.646168 0.835420908 0.943347433 0.939867802 0.830952378 0.840307804 1.059954109 0.988422092 1.374221699 1.016395289 1 13.09994708 -3.272793766 1.098551357 0.914749723 4.2663354 0.760764138 0.074033335 4.578928637 0.841948224 0.011833243 29.72511622 0.000533588 3.272793766 3.351585677 ALSAAVADSLTNS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 ALSAAVADSLTNSPR 15 0 Q14687-2;Q14687-3;Q14687;H7C3B5 Q14687-2 GSE1 Genetic suppressor element 1 1 0 ALSAAVADSLT(0.002)NS(0.998)PR;ALSAAVADSLT(0.011)NS(0.989)PR ; 226.74 1.02E-20 38443000 4229 4015.8 4762 4553.1 4346.4 6081.6 4975.2 2561.7 4415.6 3896.7 TRUE FALSE FALSE 3894.270188 4362.907858 4938.483909 4534.260479 4294.572019 4820.207606 5114.790722 3342.750537 3931.219727 4032.110035 0.965814463 1.082040872 1.224788973 1.124537882 1.065092962 1.195455373 1.268514668 0.829032568 0.974978285 1 11.97731929 -7.122096779 4.427753286 0.984132846 1.1279607 0.22413428 0.113147612 0.221941584 7.067721745 0.017506395 0.021633496 7.55E-08 7.122096779 0.143827855 ALSAIADLLTNEHER ddPTM_HeLa_Curcumin_4h_R1 2 ALSAIADLLTNEHER 15 0 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12;O60716-25;O60716-26;O60716-27;O60716-29;O60716-32;O60716-28;O60716-31;O60716-30 O60716 CTNND1 Catenin delta-1 0 0 ; ; 198.81 3.97E-07 6914800 7561.1 5327.3 6206.9 6424.1 6079.8 8276.5 5532.1 4163.8 7569 5883.5 FALSE FALSE TRUE 6962.630957 5787.768074 6436.933174 6397.518776 6007.302356 6559.860605 5687.315837 5433.323452 6738.699637 6087.951187 1.143673913 0.95069226 1.057323388 1.050849223 0.986752714 1.077515309 0.934192089 0.892471586 1.106891207 1 12.57174108 -3.355222411 0.657374594 1.058608226 0.415091307 0.446049222 0.056893992 6.544320066 0.825638652 0.011278354 4.17551382 0.000441344 3.355222411 -0.643516919 ALSGGGSVAS(ph)PPPSPAMPK ddPTM_HeLa_Curcumin_4h_R1 1 ALSGGGSVASPPPSPAMPK 19 0 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 0 ALS(0.001)GGGS(0.074)VAS(0.922)PPPS(0.003)PAMPK 103.39 0.0007397 13451000 3029.7 2158.3 2521.2 2090.7 2199 3321.4 2546.7 1347.7 2929.1 2368.9 TRUE FALSE FALSE 2789.896048 2344.853835 2614.63789 2082.049237 2172.778361 2632.5042 2618.153548 1758.607526 2607.785058 2451.219099 1.138166739 0.956607198 1.066668374 0.849393365 0.886407242 1.073957119 1.068102623 0.717441997 1.063872691 1 11.25928373 -6.287390173 23.80061025 1.057123539 0.934131885 0.249180527 0.10676297 470.5462658 431557.5018 0.016969637 0.025928246 5.16E-07 6.287390173 -0.122991654 DIIRQPS(ph)EEEIIK ddPTM_HeLa_Curcumin_4h_R1 2 DIIRQPSEEEIIK 13 1 B1AKZ5;Q15121;Q15121-2 B1AKZ5 PEA15 Astrocytic phosphoprotein PEA-15 1 0 DIIRQPS(1)EEEIIK;DIIRQPS(1)EEEIIK ; 138.28 0.0027862 72285000 3441.3 2699.6 2249.96 2774.3 2944.8 9964.2 11252.1 13585.1 4247 3843.8 TRUE FALSE FALSE 3168.917474 2932.941395 2333.345497 2762.820682 2909.685183 7897.5126 11567.80364 17727.13445 3781.114725 3977.371764 0.796736554 0.737406903 0.586655117 0.69463476 0.731559773 1.985610868 2.908403923 4.456997109 0.950656602 1 11.9575997 -4.584687177 1.330858242 0.832838834 4.91868504 0.975117787 0.191004574 0.090230268 0.205497243 0.031593848 0.422681106 2.60E-05 4.584687177 4.085846206 up ALSGVLEQDRVQS(ph)LKDKNEATVSTGK ddPTM_HeLa_Curcumin_4h_R1 1 ALSGVLEQDRVQSLKDKNEATVSTGK 26 3 Q9Y450-4;Q9Y450;E9PJ90;E9PN23;G5E991;E9PMN1;E9PLR4;Q9Y450-2 Q9Y450-4 HBS1L HBS1-like protein 1 0 ALS(0.004)GVLEQDRVQS(0.962)LKDKNEAT(0.023)VS(0.006)T(0.006)GK 48.198 0.012833 21415000 1145.3 1181.2 1185 1192.7 861.69 1167.6 644.18 854.24 1545.2 1358.7 TRUE FALSE FALSE 1054.648296 1283.297665 1228.917142 1187.764923 851.4149095 925.4265984 662.2539571 1114.693844 1375.695426 1405.914724 0.750150972 0.912784853 0.874105038 0.844834259 0.605594987 0.658238073 0.471048454 0.79286021 0.978505597 1 10.45729337 -5.809473733 4.786124652 0.880219738 0.621447502 0.629539028 0.098042494 0.115928887 5.719537854 0.016597229 0.03129687 1.55E-06 5.809473733 -0.258772236 ALSRS(ph)RRY(ph)PWR ddPTM_HeLa_Curcumin_4h_R1 1 ALSRSRRYPWR 11 3 P84996 P84996 GNAS Protein ALEX 2 0 ALS(0.104)RS(0.931)RRY(0.965)PWR 73.666 0.019084 7390600 1598.3 1336.9 1270.2 1324.1 1486.8 1669.2 1257.1 1430.2 1576.1 1324.4 TRUE FALSE FALSE 1471.792868 1452.455679 1317.274729 1318.621225 1469.070881 1322.989104 1292.370843 1866.261396 1403.205773 1370.422801 1.073969922 1.059859539 0.961217756 0.962200296 1.071983682 0.965387545 0.943045344 1.361814321 1.023921794 1 10.42040535 -4.253371466 24.9539848 1.020719831 1.361814492 0.826176445 0.048471709 330.8407431 1023263.583 0.007363441 0.107798559 5.58E-05 4.253371466 0.341094661 ALSSDS(ph)ILSPAPDAR ddPTM_HeLa_Curcumin_4h_R1 1 ALSSDSILSPAPDAR 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 ALS(0.268)S(0.195)DS(0.519)ILS(0.017)PAPDAR 90.229 0.007494 4852300 768.54 776.09 926.41 851.27 965.69 1346.5 888.03 740.98 1144.3 633.69 TRUE FALSE FALSE 707.709248 843.1717614 960.7435696 847.7476703 954.1747775 1067.220722 912.9457318 966.9013909 1018.773153 655.7106803 1.079301084 1.285889931 1.465194328 1.29286848 1.455176507 1.627578677 1.392299621 1.474585393 1.55369309 1 9.356915584 -7.086486185 1.15143898 1.022074083 1.467487977 0.041634789 0.186191384 0.112433983 0.289879425 0.016009606 0.020641196 8.19E-08 7.086486185 0.445413894 ALSSDSILS(ph)PAPDAR ddPTM_HeLa_Curcumin_4h_R1 1 ALSSDSILSPAPDAR 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 ALSSDS(0.002)ILS(0.998)PAPDAR 184 8.41E-18 0 2357.1 2025.6 2202.1 2511.8 2122.6 3091.3 2978.5 1678.2 2377.4 1930.3 TRUE FALSE FALSE 2170.533048 2200.683838 2283.711763 2501.406837 2097.289381 2450.129534 3062.068694 2189.875455 2116.605168 1997.377781 1.086691295 1.101786482 1.143354945 1.25234538 1.050021384 1.226673069 1.533044336 1.096375195 1.059691956 1 10.96389151 -5.875918523 0.316563813 1.000993787 1.374556341 0.32846408 0.119522325 1.972366529 0.319231406 0.06329057 0.266754067 1.33E-06 5.875918523 0.373562555 ALSSGGS(ph)ITSPPLS(ph)PALPK ddPTM_HeLa_Curcumin_4h_R1 1 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6-4;Q6Y7W6-5;Q6Y7W6;I1E4Y6;Q6Y7W6-3;E7ESB6;C9JHW1;C9JW88;F8WCD5;C9JPV7;C9JXQ0;C9J0V6;C9JHT0;C9JRZ2 Q6Y7W6-4 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 2 0 ALSS(0.001)GGS(0.991)IT(0.008)SPPLS(1)PALPK 192.72 1.30E-09 10443000 2692.1 1969.5 2592.7 2445.8 2464 3298.7 3446.1 1748 2787.4 2039.2 TRUE FALSE FALSE 2479.017444 2139.734804 2688.787743 2435.679928 2434.618409 2614.512436 3542.788291 2280.957153 2481.629194 2110.062048 1.174855235 1.014062504 1.274269515 1.154316732 1.153813657 1.239068983 1.67899721 1.080990559 1.176092995 1 11.04306971 -1.000000156 0.099331946 0.875358011 2.301424374 0.161734548 0.166410451 104.6429492 0.742041124 1.255044392 20.43085226 0.099999964 1.000000156 1.426066363 ALSSGGS(ph)ITSPPLSPALPK ddPTM_HeLa_Curcumin_4h_R1 1 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6-4;Q6Y7W6-5;Q6Y7W6;I1E4Y6;Q6Y7W6-3;E7ESB6;C9JHW1;C9JW88;F8WCD5;C9JPV7;C9JXQ0;C9J0V6;C9JHT0;C9JRZ2 Q6Y7W6-4 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 0 ALS(0.002)S(0.007)GGS(0.727)IT(0.228)S(0.036)PPLSPALPK 134.08 0.00018043 468860000 8180.8 6313.8 7096.3 7033.2 7122.8 9509.5 8162.7 5821.4 8131.4 8099.1 TRUE FALSE FALSE 7533.281048 6859.536738 7359.295121 7004.098482 7037.865262 7537.122506 8391.723393 7596.318062 7239.405764 8380.543122 0.898901293 0.818507421 0.878140595 0.835757108 0.839786295 0.899359671 1.001334075 0.906423122 0.863834916 1 13.03282803 -8.774825352 0.876661891 0.994201499 0.884795926 0 0.063168283 0.424015076 0.642547811 0.025853743 0.010888772 1.68E-09 8.774825352 -0.109405574 ALSSGGSIT(ph)SPPLSPALPK ddPTM_HeLa_Curcumin_4h_R1 1 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6-4;Q6Y7W6-5;Q6Y7W6;I1E4Y6;Q6Y7W6-3;E7ESB6;C9JHW1;C9JW88;F8WCD5;C9JPV7;C9JXQ0;C9J0V6;C9JHT0;C9JRZ2 Q6Y7W6-4 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 0 ALSSGGS(0.004)IT(0.498)S(0.498)PPLSPALPK 205.78 4.96E-13 487760000 2786.8 2470.4 2518.6 2417.6 2134.5 3209.3 2663.7 1798.6 2677.1 2376.4 TRUE FALSE FALSE 2566.221839 2683.930368 2611.941532 2407.596612 2109.047482 2543.655004 2738.436253 2346.98486 2383.428828 2458.979723 1.043612444 1.091481293 1.062205396 0.97910389 0.8576921 1.034435128 1.11364735 0.954454743 0.969275511 1 11.26384412 -6.240579166 23.71646641 1.030399215 0.990209675 0.10022095 0.067626087 947.1857883 1076876.343 0.010330037 0.017116646 5.75E-07 6.240579166 -0.040189539 ALSSGGSITS(ph)PPLS(ph)PALPK ddPTM_HeLa_Curcumin_4h_R1 1 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6-4;Q6Y7W6-5;Q6Y7W6;I1E4Y6;Q6Y7W6-3;E7ESB6;C9JHW1;C9JW88;F8WCD5;C9JPV7;C9JXQ0;C9J0V6;C9JHT0;C9JRZ2 Q6Y7W6-4 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 2 0 ALS(0.001)S(0.006)GGS(0.184)IT(0.125)S(0.687)PPLS(0.997)PALPK 123.59 0.00044024 97576000 4576.6 3482.7 3634.1 3398.6 3428.6 6093.8 5331.1 2982.1 4804.4 3657.3 TRUE FALSE FALSE 4214.357281 3783.729069 3768.782943 3384.537494 3387.716184 4829.877189 5480.676318 3891.328562 4277.36934 3784.390903 1.113615741 0.999825115 0.995875701 0.894341409 0.895181357 1.276262763 1.448232082 1.028257562 1.130266257 1 11.8858454 -5.241553443 24.25753642 1.024823008 1.270648996 0.459987437 0.120513379 374.3841337 456685.0449 0.01652354 0.042056038 5.73E-06 5.241553443 0.245825988 VAS(ph)EEEEVPLVVYLK ddPTM_HeLa_Curcumin_4h_R1 2 VASEEEEVPLVVYLK 15 0 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 0 VAS(1)EEEEVPLVVYLK;VAS(1)EEEEVPLVVYLK ; 188.63 3.14E-06 5018000 1448.54 998.39 1141.4 1136.85 1218.7 2372.2 2506.79 2699.67 1364.27 1233.76 TRUE FALSE FALSE 1333.886531 1084.686383 1183.701288 1132.146016 1204.167798 1880.17898 2577.123781 3522.786955 1214.612994 1276.633068 1.044847234 0.849646159 0.927205567 0.886821785 0.943237198 1.472763809 2.018687942 2.759435771 0.951419029 1 10.31812821 -4.579783746 1.408997241 0.983967272 2.971787144 0.980631007 0.083394249 0.07529759 0.198338197 0.013987699 0.178302136 2.63E-05 4.579783746 1.987819872 up ALSSLHGDDQDS(ph)EDEVLTIPEVK ddPTM_HeLa_Curcumin_4h_R1 3 ALSSLHGDDQDSEDEVLTIPEVK 23 0 P11717 P11717 IGF2R Cation-independent mannose-6-phosphate receptor 1 0 ALSSLHGDDQDS(0.898)EDEVLT(0.102)IPEVK;ALSSLHGDDQDS(0.955)EDEVLT(0.045)IPEVK;ALSSLHGDDQDS(1)EDEVLTIPEVK ;; 117.03 2.16E-06 81770300 9869.3 9141.2 8574.8 8538.6 13739.7 18456.3 6065 2170.52 16128.6 11138 TRUE FALSE FALSE 9088.134491 9931.324596 8892.589631 8503.269536 13575.86305 14628.25533 6235.167577 2832.301556 14359.33293 11525.04467 0.788555251 0.861716798 0.771588301 0.737807946 1.177944506 1.269258016 0.541010274 0.245751894 1.245924275 1 13.49248472 -4.55130858 7.316214235 0.914481669 0.316009521 0.589032202 0.196952014 0.076212588 14.72163621 0.024921227 0.097275668 2.81E-05 4.55130858 -0.598472148 ALSSS(ph)ADDASLVNASISSSVK ddPTM_HeLa_Curcumin_4h_R1 1 ALSSSADDASLVNASISSSVK 21 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 0 ALSS(0.004)S(0.996)ADDASLVNASISSSVK 230.27 2.46E-29 5265600 1302.5 1157.4 1269.6 1277.4 1207.7 1549.5 1442.9 917.25 1361.9 1428 TRUE FALSE FALSE 1199.405751 1257.440499 1316.652493 1272.114457 1193.298966 1228.116234 1483.383891 1196.915303 1212.502977 1477.622894 0.811713026 0.850988777 0.891061243 0.860919564 0.807580183 0.831143209 1.003898828 0.810027584 0.82057674 1 10.52906241 -9.41109699 1.098129563 1.001266128 0.857435651 0 0.077508109 0.353641278 0.752083908 0.039531744 0.009665498 3.88E-10 9.41109699 -0.143830476 NSK(ac)INAENK ddPTM_HeLa_Curcumin_4h_R1 1 NSKINAENK 9 1 D6RHI0;E9PC90;P14635-2;P14635 D6RHI0 CCNB1 G2/mitotic-specific cyclin-B1 0 1 NSK(1)INAENK 91.937 0.018126 1898500 474.31 626.27 453.17 343.87 217.49 733.83 717.49 821.05 481.78 475.35 FALSE TRUE FALSE 436.767863 680.4019882 469.9648788 342.4471571 214.8965738 581.625386 737.6208384 1071.384365 428.9299394 491.8683771 0.887977116 1.38330094 0.955468781 0.696217063 0.436898536 1.182481764 1.499630537 2.178193222 0.872042114 1 8.942128495 -4.474803642 1.902944904 0.931249117 2.284894208 0.743460961 0.234249695 0.206191072 1.05680323 0.034422895 0.420935058 3.35E-05 4.474803642 1.353645091 up ALSSSK(ac)QSSSSRDDNMFQIGK ddPTM_HeLa_Curcumin_4h_R1 2 ALSSSKQSSSSRDDNMFQIGK 21 2 P53999 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 0 1 ; ALSSSK(1)QSSSSRDDNMFQIGK;ALSSSK(1)QSSSSRDDNMFQIGK 200.45 1.79E-60 6003600 2047.55 1467.83 1470.42 1635.59 1311.61 2954.59 2135.72 2588.05 2492.5 1946.58 FALSE TRUE FALSE 1885.484257 1594.702685 1524.915059 1628.822362 1295.969907 2341.774729 2195.642555 3377.134531 2219.078986 2014.22351 0.936084922 0.791720818 0.757073409 0.808660188 0.643409185 1.162619102 1.090068974 1.676643388 1.101704441 1 10.97600807 -4.041705605 1.376225928 0.912862201 2.334722312 0.72289226 0.14634693 0.87385899 0.985194115 0.021480069 1.981801544 9.08E-05 4.041705605 1.421860111 ALST(ph)TSSSTTNGNR ddPTM_HeLa_Curcumin_4h_R1 1 ALSTTSSSTTNGNR 14 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;C9JUH3;Q9BSQ5-3 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 0 ALS(0.302)T(0.687)T(0.007)S(0.001)S(0.001)S(0.001)TTNGNR 124.47 0.0041082 11744000 1435.3 1107.5 1091.4 1397.7 1341.2 1709.4 1022.7 948.51 1341.3 1119.3 TRUE FALSE FALSE 1321.69449 1203.227365 1131.848244 1391.916688 1325.207066 1354.851171 1051.39421 1237.706333 1194.162746 1158.195592 1.141166915 1.038880975 0.977251383 1.201797605 1.144199715 1.169794792 0.907786402 1.06865053 1.031054473 1 10.1776632 -9.598046177 1.395034653 1.000020233 1.08815054 0.077976316 0.085973139 0.754596659 2.635840728 0.061908549 0.01434032 2.52E-10 9.598046177 0.088130307 ALSTDPAAPNLK ddPTM_HeLa_Curcumin_4h_R1 2 ALSTDPAAPNLK 12 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 ; ; 194.94 3.68E-14 5622900 9091.4 7047.8 7378.9 8142.2 8456.5 10014 7481 6936.1 9093.7 8188.2 FALSE FALSE TRUE 8371.806097 7656.980428 7652.368525 8108.509734 8355.661761 7936.983519 7690.896726 9050.88496 8096.143861 8472.739341 0.988087295 0.903719579 0.903175256 0.957011588 0.98618185 0.936767107 0.90772257 1.068235974 0.955552099 1 13.04861277 -7.482295174 18.94340853 0.994744721 0.948967928 0.05108203 0.04820015 33.9879346 15865.51321 0.007614775 0.008581727 3.29E-08 7.482295174 -0.045776793 ALSTGEK(ac)GFGYK ddPTM_HeLa_Curcumin_4h_R1 2 ALSTGEKGFGYK 12 1 P62937;F8WE65;C9J5S7 P62937 PPIA "Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase" 0 1 ; ALSTGEK(1)GFGYK;ALSTGEK(1)GFGYK 202.16 2.76E-20 26308000 4538.7 3724.6 3482.3 3970.1 3691.7 5850.5 4799.7 4483.1 4517.6 3690.9 FALSE TRUE FALSE 4179.457106 4046.537828 3611.357101 3953.672778 3647.678889 4637.040351 4934.366664 5849.976552 4022.030582 3819.1585 1.094339789 1.059536499 0.945589742 1.03522092 0.955100158 1.214152372 1.292003635 1.531744899 1.053119577 1 11.89903908 -4.571535318 1.399759771 1.033573459 1.583175379 0.894172068 0.05596243 0.178935239 0.459220537 0.008928817 0.117142619 2.68E-05 4.571535318 0.54960192 ALSTGLDYS(ph)PPSAPR ddPTM_HeLa_Curcumin_4h_R1 1 ALSTGLDYSPPSAPR 15 0 P54253 P54253 ATXN1 Ataxin-1 1 0 ALSTGLDYS(0.998)PPS(0.002)APR 187.08 1.25E-05 8305600 1631.4 1273.7 1107.6 1292.3 1466.7 1604 1541.3 1118 1680.2 1209.2 TRUE FALSE FALSE 1502.272969 1383.792953 1148.64863 1286.952805 1449.21056 1271.312319 1584.54473 1458.873053 1495.886264 1251.21961 1.200646918 1.105955295 0.9180232 1.028558692 1.158238369 1.016058499 1.266400172 1.165960829 1.195542534 1 10.28911931 -4.757810111 24.9999672 1.080409325 1.216180514 0.27855337 0.088955711 100.0984752 689490.4563 0.013649302 0.047341068 1.75E-05 4.757810111 0.135771188 ALSTPVVEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 ALSTPVVEKR 10 1 E5RH41;P29084;E5RK24;E5RIW4 E5RH41 GTF2E2 Transcription initiation factor IIE subunit beta 0 1 ; ALSTPVVEK(1)R;ALSTPVVEK(1)R 78.098 0.014166 2411900 1247.15 1210.82 1377.82 1179.71 1023.1 1213.52 1106.7 1133.16 1254.09 1507.61 FALSE TRUE FALSE 1148.436762 1315.477885 1428.883221 1174.828673 1010.900201 961.8222728 1137.751023 1478.655268 1116.519465 1559.999335 0.736177725 0.843255414 0.915951173 0.753095624 0.648013225 0.616553002 0.72932789 0.947856345 0.71571791 1 10.6073297 -10.22544004 0.39337364 1.195986215 0.751647113 0 0.135065845 3.701091001 0.429227513 0.761505445 0.03382735 5.95E-11 10.22544004 -0.444339102 ALSTTS(ph)SSTTNGNR ddPTM_HeLa_Curcumin_4h_R1 1 ALSTTSSSTTNGNR 14 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;C9JUH3;Q9BSQ5-3 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 0 ALS(0.027)T(0.027)T(0.027)S(0.306)S(0.306)S(0.306)TTNGNR 170.95 0.00020107 14374000 2258 1489.7 1551.8 1840.3 1935.4 1931.5 1260.2 1440.2 1786.4 1856.2 TRUE FALSE FALSE 2079.276917 1618.46303 1609.311073 1832.685326 1912.321619 1530.885128 1295.55782 1879.31035 1590.436389 1920.702812 1.082560459 0.842641048 0.837876148 0.954174334 0.995636393 0.797044248 0.67452279 0.978449315 0.828049181 1 10.90741859 -7.257225798 24.8395847 1.038986884 0.86539564 0.054710784 0.113100951 234.1807268 1380525.249 0.015899238 0.019099814 5.53E-08 7.257225798 -0.173591244 ALSYASLDKEDLLS(ph)PINQNTLQR ddPTM_HeLa_Curcumin_4h_R1 1 ALSYASLDKEDLLSPINQNTLQR 23 1 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 0 ALSYASLDKEDLLS(0.906)PINQNT(0.094)LQR 67.01 0.00092867 17362000 1554.7 1166.4 1403.6 1438.8 1269.8 2343.7 1987 1181.7 1898.1 1694.2 TRUE FALSE FALSE 1431.643854 1267.218419 1455.618651 1432.846627 1254.658464 1857.590201 2042.749872 1541.99489 1689.883179 1753.073324 0.816648017 0.722855343 0.830323884 0.817334111 0.715690808 1.059619227 1.165239265 0.879595205 0.963954648 1 10.77567062 -5.22086988 24.69678962 0.871707487 1.04786014 0.375018517 0.110180091 441.2884553 268634.7409 0.017535107 0.044705305 6.01E-06 5.22086988 0.176152654 ALTDDS(ph)DENEEEDAFTDQK ddPTM_HeLa_Curcumin_4h_R1 1 ALTDDSDENEEEDAFTDQK 19 0 A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;Q8NI35-5;A0A0U1RRD7;A0A0U1RQW4 A0A2R8Y549 INADL InaD-like protein 1 0 ALT(0.003)DDS(0.997)DENEEEDAFTDQK 170.92 2.27E-06 6619600 4388 3060.3 3647.4 3745.9 3837.6 4511.9 3156.1 2929.6 4230.9 3432.6 TRUE FALSE FALSE 4040.68517 3324.818696 3782.575853 3730.400458 3791.839126 3576.08108 3244.651672 3822.821554 3766.780855 3551.882594 1.137617886 0.93607224 1.064949573 1.050260069 1.067557563 1.006812862 0.913501949 1.076280381 1.060502636 1 11.79436818 -5.136028857 4.949989935 1.055382564 0.987413423 0.089293352 0.06148442 0.326792205 11.7779952 0.009753235 0.025825542 7.31E-06 5.136028857 -0.06796914 ALTGGIAHLFK(ac)QNK ddPTM_HeLa_Curcumin_4h_R1 1 ALTGGIAHLFKQNK 14 1 E9PEX6;P09622-2;P09622-3;P09622 E9PEX6 DLD "Dihydrolipoyl dehydrogenase;Dihydrolipoyl dehydrogenase, mitochondrial" 0 1 ALTGGIAHLFK(1)QNK 114.87 0.0007722 1472400 2057.1 724.95 1429.6 1223.6 1625.2 3085.1 1757.8 1453.8 1609.3 1292.7 FALSE TRUE FALSE 1894.278364 787.6114477 1482.582234 1218.537067 1605.820551 2445.215484 1807.119137 1897.056928 1432.763816 1337.621229 1.416154531 0.588815003 1.108372237 0.910973182 1.200504685 1.828032803 1.35099466 1.418231773 1.071128198 1 10.38545393 -5.496274516 22.71599064 1.122478561 1.514276125 0.449945134 0.23831541 218.672752 186712.2708 0.037991118 0.08460767 3.19E-06 5.496274516 0.391797564 ALTHNGT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 ALTHNGTPR 9 0 Q9HB90 Q9HB90 RRAGC Ras-related GTP-binding protein C 1 0 ALTHNGT(1)PR 89.266 0.019373 4591600 4539.2 5281.6 3960.8 2806.7 3383.2 4176.2 2742.4 884.88 4444.5 4195.6 TRUE FALSE FALSE 4179.91753 5738.11797 4107.590732 2795.086619 3342.85755 3310.009045 2819.344363 1154.675839 3956.94947 4341.396788 0.962804769 1.321721614 0.94614497 0.643821967 0.769995859 0.762429514 0.649409511 0.265968741 0.911446169 1 12.08394357 -4.387732835 0.543001132 1.005398335 3.34E-15 0.678774634 0.150122153 1.565116127 0.337262108 0.030268228 0.964830901 4.10E-05 4.387732835 -1.005398335 ALTPGLSWLLQRMQARAAGQT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 ALTPGLSWLLQRMQARAAGQTPK 23 2 Q6P5W5-2;Q6P5W5 Q6P5W5-2 SLC39A4 Zinc transporter ZIP4 1 0 ALTPGLS(0.001)WLLQRMQARAAGQT(0.998)PK 47.392 0.0080493 0 1599.9 1802.9 1482.5 1929 1496.1 1539.5 1660.9 1322.9 1942.2 2371.5 TRUE FALSE FALSE 1473.266227 1958.734642 1537.442754 1921.018309 1478.259985 1220.190346 1707.500384 1726.24612 1729.145519 2453.909448 0.600375139 0.798209829 0.626527908 0.782839933 0.60241016 0.497243428 0.695828603 0.703467734 0.704649277 1 11.2608663 -9.40276384 0.746378685 1.04142332 0.656567367 0.100488554 0.124566469 0.408615645 0.334336337 0.101652927 0.017201752 3.96E-10 9.40276384 -0.384855953 ALTQTGGPHVK ddPTM_HeLa_Curcumin_4h_R1 4 ALTQTGGPHVK 11 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ;;; ;;; 120.55 0.00057689 43243400 10184.3 9616 8750.6 8583.5 9197.3 14429.6 10718.6 9190.1 11981.9 9519.8 FALSE FALSE TRUE 9378.201909 10447.16419 9074.904934 8547.983751 9087.628204 11436.7383 11019.33507 11992.11918 10667.51555 9850.612341 0.952042531 1.060559875 0.921252874 0.867761663 0.922544497 1.161018007 1.118644678 1.217398347 1.08292918 1 13.26599769 -5.253097278 24.52359627 0.967359552 1.160982803 0.648502658 0.065093655 198.2804914 582890.2776 0.008043235 0.020129151 5.58E-06 5.253097278 0.193623251 ALTVPELT(ph)QQVFDAK ddPTM_HeLa_Curcumin_4h_R1 1 ALTVPELTQQVFDAK 15 0 Q5JP53;P07437;Q5ST81 Q5JP53 TUBB Tubulin beta chain 1 0 ALTVPELT(1)QQVFDAK 97.813 0.013657 13415000 1598.1 1612.4 1470 1343.1 1345.6 2041.1 1312 1288.5 1556.7 1521.6 TRUE FALSE FALSE 1471.608699 1751.768671 1524.479493 1337.542608 1329.554599 1617.752852 1348.811189 1681.357718 1385.933905 1574.475487 0.934665996 1.112604601 0.968245937 0.849516312 0.84444287 1.027486846 0.856673349 1.067884342 0.88025118 1 10.62065558 -6.502553261 24.90948915 0.981967909 0.924218821 0.074513827 0.088196366 1335.758159 1637011.996 0.012327922 0.01868638 3.14E-07 6.502553261 -0.057749088 ALTVPELTQQMFDAK ddPTM_HeLa_Curcumin_4h_R1 2 ALTVPELTQQMFDAK 15 0 P04350;P68371;A0A0B4J269;Q13509;Q13509-2 P04350;P68371;A0A0B4J269 TUBB4A;TUBB4B;TUBB3 Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-3 chain 0 0 ; ; 214.82 1.79E-13 83539000 6259.7 4894 5654 5042.9 5045.1 7623.4 5033.6 5033.2 5546.5 4953.4 FALSE FALSE TRUE 5764.23814 5317.015553 5863.542214 5022.033816 4984.940478 6042.220907 5174.829269 6567.79951 4938.062827 5125.530281 1.12461303 1.037359114 1.14398743 0.979807657 0.972570681 1.178847958 1.009618319 1.281389271 0.963424769 1 12.32348556 -5.209149765 0.010875623 1.17E-06 2.202281607 0.194372419 0.091349183 5696.777282 13.86625288 1329.163594 1481.035634 6.18E-06 5.209149765 2.20228044 ALTVPELTQQMFDSK ddPTM_HeLa_Curcumin_4h_R1 3 ALTVPELTQQMFDSK 15 0 Q9BVA1;Q13885 Q9BVA1 TUBB2B;TUBB2A Tubulin beta-2B chain;Tubulin beta-2A chain 0 0 ;; ;; 172.98 0.00068345 52240000 5561.3 5229.8 5347.9 5203.2 4610.3 7418 5496 5098.64 5700.6 5073.44 FALSE FALSE TRUE 5121.117237 5681.840608 5546.097878 5181.670537 4555.325184 5879.423182 5650.202968 6653.191865 5075.258442 5249.741662 0.975498904 1.082308611 1.056451581 0.987033433 0.867723686 1.119945239 1.076282098 1.267337003 0.966763465 1 12.35803071 -4.157989233 1.21883263 0.99538051 1.429860567 0.618437166 0.06331397 0.879475405 0.921568434 0.009091519 0.508994427 6.95E-05 4.157989233 0.434480057 ALTVPELTQQVFDAK ddPTM_HeLa_Curcumin_4h_R1 1 ALTVPELTQQVFDAK 15 0 Q5JP53;P07437;Q5ST81 Q5JP53 TUBB Tubulin beta chain 0 0 158.42 0.0028584 8765500 1549.8 1399.7 1483.9 1427.9 1228.4 1880.9 1468.2 1415.9 1447.4 1541.6 FALSE FALSE TRUE 1427.131695 1520.683831 1538.894639 1421.991728 1213.752132 1490.780138 1509.393741 1847.601392 1288.623841 1595.170485 0.894657786 0.953304894 0.964721109 0.891435581 0.760891794 0.934558501 0.946227224 1.158246977 0.807828287 1 10.63949491 -4.259931559 4.46050302 0.932148039 1.173943081 0.48737801 0.073461802 0.138065935 6.804213343 0.009864179 0.104879754 5.50E-05 4.259931559 0.241795042 ALVATPGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 ALVATPGKK 9 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 ; ALVATPGK(1)K;ALVATPGK(1)K 160.88 7.81E-09 618820000 27478 21385.6 24191 23241 23248 29266 27727 25261 25657 20329.2 FALSE TRUE FALSE 25303.08731 23234.07597 25087.53974 23144.8349 22970.78278 23195.9017 28504.945 32962.96261 22842.49129 21035.63819 1.202867585 1.104510154 1.192620805 1.100267779 1.091993624 1.102695411 1.355078688 1.567005589 1.085894856 1 14.36054797 -4.52787923 2.345650286 1.104715685 1.577740361 0.876761268 0.055299609 0.122271903 1.129111595 0.011263019 0.092692993 2.97E-05 4.52787923 0.473024676 ALVATPGKK ddPTM_HeLa_Curcumin_4h_R1 1 ALVATPGKK 9 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 0 82.75 0.012467 0 3489.5 2492 2571.2 2719.4 2974.8 3234.6 2650.9 2812 2930.2 2694.3 FALSE FALSE TRUE 3213.302393 2707.397376 2666.490934 2708.147843 2939.327453 2563.707499 2725.277119 3669.365855 2608.764391 2787.926724 1.152577779 0.971114969 0.956442259 0.971384154 1.054305849 0.919574921 0.977528245 1.316162948 0.935736355 1 11.44497693 -11.67798677 12.41557649 0.557885617 1.048379539 0 0.118148431 0 0 0 0.01514664 2.10E-12 11.67798677 0.490493921 ALVDHENVISCPHLGASTK ddPTM_HeLa_Curcumin_4h_R1 1 ALVDHENVISCPHLGASTK 19 0 A0A286YF22;A0A2C9F2M7;O43175;A0A286YFL2;A0A286YFA2;A0A286YF78 A0A286YF22 PHGDH D-3-phosphoglycerate dehydrogenase 0 0 84.653 0.002629 2742800 2610.4 2408.3 2440.9 2388.8 2572.1 5975.4 2773.9 2298 3163.5 2584.6 FALSE FALSE TRUE 2403.784086 2616.462721 2531.361901 2378.915779 2541.429387 4736.034683 2851.728168 2998.649621 2816.471965 2674.414658 0.89880755 0.978330983 0.94651063 0.889508952 0.950274999 1.770867756 1.066299932 1.121235861 1.053117158 1 11.38500745 -5.438890654 24.99999359 0.947714089 1.305222615 0.451742233 0.181196797 55.38289386 16484.51734 0.023717827 0.053034669 3.64E-06 5.438890654 0.357508527 ALVEFESNPEET(ph)REPGSPPSVQR ddPTM_HeLa_Curcumin_4h_R1 2 ALVEFESNPEETREPGSPPSVQR 23 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 0 ALVEFES(0.029)NPEET(0.9)REPGS(0.071)PPS(0.001)VQR;ALVEFES(0.001)NPEET(0.552)REPGS(0.424)PPS(0.023)VQR ; 60.454 0.0061033 539829500 4132.93 3706.38 4090.8 3943.94 4100.04 4481 3633.43 2497.17 4540.86 4096.3 TRUE FALSE FALSE 3805.804229 4026.742972 4242.408647 3927.621021 4051.149701 3551.590089 3735.374267 3258.545637 4042.739019 4238.64612 0.897882041 0.950006879 1.000887672 0.926621593 0.955765022 0.837906725 0.881265895 0.768770392 0.953780737 1 12.04938781 -2.683559555 0.485563861 0.957370942 4.58E-18 0.719507665 0.036628964 8.487895682 0.415018041 0.009239228 6.557899652 0.002072242 2.683559555 -0.957370942 ALVEFESNPEETREPGS(ph)PPSVQR ddPTM_HeLa_Curcumin_4h_R1 2 ALVEFESNPEETREPGSPPSVQR 23 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 0 ALVEFESNPEET(0.017)REPGS(0.981)PPS(0.002)VQR;ALVEFESNPEET(0.256)REPGS(0.741)PPS(0.003)VQR ; 102.24 1.60E-05 2842800000 4319.4 3505.8 3786.6 3480.7 3378.5 4679.6 3212.4 1877.08 3969.9 3558 TRUE FALSE FALSE 3977.514932 3808.82573 3926.934727 3466.297786 3338.213594 3708.99821 3302.531298 2449.393051 3534.411902 3681.640235 1.080364913 1.034545878 1.066626415 0.9415091 0.90671912 1.00743092 0.897027164 0.665299403 0.960010125 1 11.84613294 -3.56640685 0.722669046 1.033681094 9.27E-22 0.767586118 0.054775362 2.176003663 0.394075469 0.009145177 2.321080091 0.00027139 3.56640685 -1.033681094 SPSLSPSPPS(ph)PLEK ddPTM_HeLa_Curcumin_4h_R1 3 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 SPSLSPS(0.02)PPS(0.98)PLEK;S(0.003)PS(0.001)LS(0.003)PS(0.019)PPS(0.974)PLEK;SPSLS(0.001)PS(0.064)PPS(0.935)PLEK ;; 184.51 6.60E-05 812571000 8404.2 6720.9 7163.2 7577.5 9982.9 18337.3 23591.1 25464.1 8029.1 7356.3 TRUE FALSE FALSE 7738.998702 7301.824648 7428.674493 7546.146313 9863.860438 14533.93728 24253.00277 33227.98687 7148.327818 7611.930877 1.016693245 0.959260504 0.975925112 0.991357703 1.295842093 1.90936275 3.186182739 4.365250736 0.939095209 1 12.89404675 -4.579760495 1.186065664 0.995267011 5.022106984 0.998507409 0.043396706 0.024868742 0.041594924 0.00700358 0.106651865 2.63E-05 4.579760495 4.026839973 up ALVILAK ddPTM_HeLa_Curcumin_4h_R1 2 ALVILAK 7 0 Q99497;K7ELW0 Q99497 PARK7 Protein deglycase DJ-1 0 0 ; ; 148.12 0.0014708 15317800 12461.1 8174.6 10955.2 9633.1 9731.7 14908.9 12560.5 13433.5 11036 10072 FALSE FALSE TRUE 11474.79079 8881.175999 11361.20935 9593.240785 9615.655833 11816.62608 12912.91383 17529.31231 9825.378411 10422.00125 1.101016063 0.852156489 1.090117826 0.920479719 0.922630462 1.133815454 1.239005208 1.68195262 0.942753524 1 13.34734471 -4.207994288 1.50557869 1.021134625 1.997691926 0.860444236 0.085001013 0.351227119 0.654541335 0.012396581 0.52721956 6.19E-05 4.207994288 0.976557301 ALVIVMGK ddPTM_HeLa_Curcumin_4h_R1 1 ALVIVMGK 8 0 C9J0J7;G5E9Q6;P35080-2 C9J0J7 PFN2 Profilin;Profilin-2 0 0 146.21 1.13E-13 0 2600.4 1637.8 1892.3 1531.1 1883 2952.5 2322.8 1958.7 1950.6 1826.9 FALSE FALSE TRUE 2394.575596 1779.364134 1962.430303 1524.764714 1860.546455 2340.118218 2387.971517 2555.898613 1736.62406 1890.384639 1.266713423 0.941270944 1.038111643 0.806589666 0.984215813 1.237905858 1.263219912 1.352052149 0.91866175 1 10.8844641 -5.080891717 4.612821531 1.075181939 1.296884351 0.438447855 0.13081324 0.217900582 8.287618441 0.021933627 0.059676842 8.30E-06 5.080891717 0.221702412 ALVLDCHYPEDEVGQEDEAES(ph)DIFSIR ddPTM_HeLa_Curcumin_4h_R1 1 ALVLDCHYPEDEVGQEDEAESDIFSIR 27 0 Q07021;I3L3Q7;I3L3B0 Q07021 C1QBP "Complement component 1 Q subcomponent-binding protein, mitochondrial" 1 0 ALVLDCHYPEDEVGQEDEAES(0.989)DIFS(0.011)IR 89.239 6.31E-06 3603300 796.7 686.65 984.29 836.19 835.31 1277.7 896.95 924 937.98 765.93 TRUE FALSE FALSE 733.6403543 746.0009663 1020.768653 832.7300673 825.3494738 1012.690617 922.116003 1205.723346 835.0859407 792.5460105 0.925675411 0.941271493 1.28796138 1.050702491 1.04138998 1.277768866 1.163485767 1.521329147 1.053675029 1 9.630350882 -1.000000004 0.348043696 0.963550998 6.845758316 0.624272192 0.108815705 22.63982366 0.284016634 0.030839074 88.38844266 0.099999999 1.000000004 5.882207318 ALVLDCHYPEDEVGQEDEAESDIFSIR ddPTM_HeLa_Curcumin_4h_R1 1 ALVLDCHYPEDEVGQEDEAESDIFSIR 27 0 Q07021;I3L3Q7;I3L3B0 Q07021 C1QBP "Complement component 1 Q subcomponent-binding protein, mitochondrial" 0 0 65.428 0.00074634 6977800 1017.4 605.74 616.87 1005 1116.3 1406.2 634.47 870.98 1260 816.17 FALSE FALSE TRUE 936.8717164 658.0974665 639.7317449 1000.841576 1102.988852 1114.538269 652.2715206 1136.537793 1121.781152 844.5318467 1.109338529 0.779245293 0.757498663 1.18508447 1.30603583 1.319711356 0.772346861 1.345760728 1.328287567 1 9.722008017 ALVVPEPEPDS(ph)DS(ph)NQER ddPTM_HeLa_Curcumin_4h_R1 1 ALVVPEPEPDSDSNQER 17 0 C9J0A5;C9JXC9;Q5VTR2 C9J0A5 RNF20 E3 ubiquitin-protein ligase BRE1A 2 0 ALVVPEPEPDS(1)DS(1)NQER 89.468 0.010848 6712000 3504.6 2459.3 3116.1 3282.7 3506.5 3615.4 3957.5 4008.4 3159.8 3509.9 TRUE FALSE FALSE 3227.207212 2671.870934 3231.585407 3269.117057 3464.687278 2865.525286 4068.536799 5230.542708 2813.177845 3631.868764 0.888580349 0.735673866 0.889785842 0.90011982 0.953968192 0.788994722 1.120232328 1.440179436 0.77458136 1 11.82649636 -4.407243736 3.004661609 0.915919543 1.455691776 0.784915592 0.090913578 0.105094078 1.533336079 0.012487637 0.11119894 3.92E-05 4.407243736 0.539772233 ALVVPEPEPDS(ph)DSNQER ddPTM_HeLa_Curcumin_4h_R1 4 ALVVPEPEPDSDSNQER 17 0 C9J0A5;C9JXC9;Q5VTR2 C9J0A5 RNF20 E3 ubiquitin-protein ligase BRE1A 1 0 ALVVPEPEPDS(0.644)DS(0.356)NQER;ALVVPEPEPDS(0.967)DS(0.033)NQER;ALVVPEPEPDS(0.955)DS(0.045)NQER;ALVVPEPEPDS(0.93)DS(0.07)NQER ;;; 172.56 4.51E-05 232790000 14427.3 11642.5 13574.9 12706.2 12705.7 15632.8 12167.3 11677.6 13616.3 12804.4 TRUE FALSE FALSE 13285.36398 12648.82582 14077.99774 12653.62511 12554.19283 12390.38106 12508.68169 15238.04648 12122.62596 13249.35195 1.002718022 0.954675057 1.062542364 0.955037285 0.947532595 0.935168838 0.944097624 1.150097495 0.914959917 1 13.69363418 ALVVPEPEPDSDS(ph)NQER ddPTM_HeLa_Curcumin_4h_R1 2 ALVVPEPEPDSDSNQER 17 0 C9J0A5;C9JXC9;Q5VTR2 C9J0A5 RNF20 E3 ubiquitin-protein ligase BRE1A 1 0 ALVVPEPEPDS(0.088)DS(0.912)NQER;ALVVPEPEPDS(0.198)DS(0.802)NQER ; 224.36 1.58E-16 12978200 4554.8 4043.1 4558.3 4330 4430.5 5150.3 5196.1 4387.8 4812.2 4642.5 TRUE FALSE FALSE 4194.282774 4392.567548 4727.234608 4312.083607 4377.669181 4082.069724 5341.888581 5725.620021 4284.3137 4803.826529 0.873112871 0.914389294 0.98405606 0.897635162 0.91128794 0.849753774 1.11200697 1.191887339 0.891854373 1 12.22996834 -4.61914369 5.139511891 0.930538458 1.173401803 0.807370909 0.046381712 0.073439663 3.039621419 0.007904706 0.03162761 2.40E-05 4.61914369 0.242863345 ALVVPEPEPDSDS(ph)NQERK ddPTM_HeLa_Curcumin_4h_R1 1 ALVVPEPEPDSDSNQERK 18 1 C9J0A5;C9JXC9;Q5VTR2 C9J0A5 RNF20 E3 ubiquitin-protein ligase BRE1A 1 0 ALVVPEPEPDS(0.228)DS(0.772)NQERK 142.43 1.06E-06 0 2300.4 2595.9 2455.9 2629.4 2209 2726.9 2787.2 2474 2486.1 2697.8 TRUE FALSE FALSE 2118.320913 2820.278029 2546.917814 2618.520239 2182.659118 2161.310202 2865.401331 3228.311211 2213.38105 2791.548349 0.758833682 1.010291665 0.912367438 0.938017155 0.78188118 0.774233483 1.026455921 1.156459 0.792886518 1 11.44684983 -4.540594559 5.208953554 0.884870901 1.130190005 0.508979329 0.089847064 0.116741109 9.121184867 0.014763825 0.064795206 2.88E-05 4.540594559 0.245319104 ALYDYAGQEADELS(ph)FR ddPTM_HeLa_Curcumin_4h_R1 2 ALYDYAGQEADELSFR 16 0 A0A0C4DGG1;Q9UKS6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 0 ALYDYAGQEADELS(1)FR;ALYDYAGQEADELS(1)FR ; 205.15 2.19E-10 33121000 4767.71 4054.68 4441.57 4387.01 5209.98 7460.3 6379.36 5862.9 4826.78 3906.71 TRUE FALSE FALSE 4390.340723 4405.148472 4606.178491 4368.857715 5147.854391 5912.949685 6558.347672 7650.471221 4297.29431 4042.467882 1.086054571 1.089717618 1.139447146 1.080740242 1.273443486 1.462707895 1.622362345 1.892524924 1.063037341 1 11.9810206 -4.185059957 0.556545075 1.034915044 2.566493004 0.982874313 0.036636846 0.360658721 0.070854752 0.007861943 0.362804511 6.53E-05 4.185059957 1.53157796 ALYDYEGQEHDELSFK ddPTM_HeLa_Curcumin_4h_R1 2 ALYDYEGQEHDELSFK 16 0 H0Y923;A0A0U1RR22;Q9UNF0-2;Q9UNF0 H0Y923 PACSIN2 Protein kinase C and casein kinase substrate in neurons protein 2 0 0 ; ; 125.67 0.00046935 6450100 6305.3 5473.5 5352.7 5487.5 5588.3 5895 5034.6 4718 6570.2 5849.5 FALSE FALSE TRUE 5806.228852 5946.604951 5551.075771 5464.794179 5521.663172 4672.31055 5175.857326 6156.496481 5849.465498 6052.76969 0.959268095 0.982460139 0.917113331 0.902858437 0.912253969 0.771929346 0.855122133 1.017137079 0.966411378 1 12.56337974 -6.54152086 1.253836321 0.982442356 0.879512206 0.316282206 0.058007415 0.339843152 1.068713859 0.010144862 0.017065174 2.87E-07 6.54152086 -0.102930149 ALYEAGER ddPTM_HeLa_Curcumin_4h_R1 1 ALYEAGER 8 0 P04083 P04083 ANXA1 Annexin A1 0 0 110.31 0.0063299 10595000 3290.1 2686.8 2887.1 3207.6 2795.6 3650.6 3284.4 3258.4 3982.5 2898.1 FALSE FALSE TRUE 3029.685113 2919.03502 2994.098466 3194.327801 2762.264296 2893.424409 3376.551424 4251.87116 3545.629714 2998.808759 1.010296206 0.97339819 0.998429278 1.065198903 0.921120524 0.964857929 1.12596424 1.417853388 1.182346057 1 11.55017381 -4.326779587 2.547360844 0.998682551 1.475257299 0.756053416 0.0685722 0.07557371 0.67946775 0.004979035 0.07215565 4.71E-05 4.326779587 0.476574748 ALYESELADARR ddPTM_HeLa_Curcumin_4h_R1 1 ALYESELADARR 12 1 Q03252 Q03252 LMNB2 Lamin-B2 0 0 166.29 0.00017941 4300000 2193.1 1897.7 1907.6 2036.6 1882.7 2150.4 1874.9 1807.5 2692.4 2665.2 FALSE FALSE TRUE 2019.513821 2061.728732 1978.297334 2028.173089 1860.250032 1704.3828 1927.504648 2358.598429 2397.050456 2757.815502 0.732287501 0.747594874 0.717342162 0.735427402 0.674537521 0.618019153 0.698924437 0.855241559 0.869184488 1 11.42931023 -9.147414094 0.534291643 1.046707613 0.707486458 0.574012004 0.069348151 0.46070854 0.195206268 0.079311761 0.014724207 7.12E-10 9.147414094 -0.339221155 ALYETELADARR ddPTM_HeLa_Curcumin_4h_R1 2 ALYETELADARR 12 1 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 0 0 ; ; 173.64 0.00020213 20748700 7601.8 5649.1 5896.1 5944.8 5341.8 7971.1 4707.3 4752.3 7487.7 7160.5 FALSE FALSE TRUE 7000.109509 6137.383032 6114.614653 5920.201993 5278.102524 6317.804007 4839.374169 6201.254393 6666.318043 7409.326842 0.944769971 0.828332069 0.825259134 0.799020224 0.712359252 0.852682591 0.653146267 0.836952469 0.899719797 1 12.85512676 -7.123119961 0.872579423 0.987034606 0.760508571 0.585303685 0.062210392 0.170586578 0.259427523 0.01130409 0.014561333 7.53E-08 7.123119961 -0.226526035 DSHS(ph)PDLQLPTPEVIPSSGSK ddPTM_HeLa_Curcumin_4h_R1 2 DSHSPDLQLPTPEVIPSSGSK 21 0 H3BPE1;H3BQK9;H0Y6T5;H0Y4F5 H3BPE1 MACF1 1 0 DS(0.187)HS(0.813)PDLQLPTPEVIPSSGSK;DS(0.266)HS(0.734)PDLQLPTPEVIPSSGSK ; 129.22 9.72E-06 21060000 12928.3 11347.6 11554.8 10507.2 9287.5 5330.5 3246.8 1162.85 12083.6 10194.8 TRUE FALSE FALSE 11905.01141 12328.43598 11983.03105 10463.72399 9176.752628 4224.894213 3337.89647 1517.397612 10758.05931 10549.06854 1.128536739 1.168675313 1.135932619 0.991909755 0.869911177 0.400499266 0.316416227 0.143841857 1.019811301 1 13.364828 -5.252411662 1.543236224 1.077094072 0.19493705 0.971508559 0.061038583 0.054459196 0.241516456 0.010908488 0.040590829 5.59E-06 5.252411662 -0.882157022 down AMDNHS(ph)DS(ph)EEELAAFCPQLDDSTVAR ddPTM_HeLa_Curcumin_4h_R1 1 AMDNHSDSEEELAAFCPQLDDSTVAR 26 0 K7EQI9;Q86VR2-2;Q86VR2 K7EQI9 FAM134C Protein FAM134C 2 0 AMDNHS(1)DS(1)EEELAAFCPQLDDSTVAR 61.141 0.0033851 0 815.21 668.36 1006.4 1010.4 762.46 675.31 422.96 685.05 907.24 867 TRUE FALSE FALSE 750.6852683 726.1300602 1043.698069 1006.219233 753.3681625 535.2430937 434.8271193 893.9185914 807.7180418 897.1281855 0.836764779 0.809393877 1.163376746 1.121600289 0.839755316 0.596618301 0.484687836 0.996422369 0.900337382 1 9.809170328 -5.480020653 5.912787562 0.945582683 0.676670135 0.369757077 0.161106734 0.173368969 15.68956886 0.023524376 0.052233336 3.31E-06 5.480020653 -0.268912548 AMEAVAAQGK ddPTM_HeLa_Curcumin_4h_R1 1 AMEAVAAQGK 10 0 P18669;P15259 P18669 PGAM1;PGAM2 Phosphoglycerate mutase 1;Phosphoglycerate mutase 2 0 0 131.06 0.014492 10372000 2312.4 1669.1 1891.8 2308.8 1681 2058 2389.8 1655.2 2500 2043.3 FALSE FALSE TRUE 2129.3711 1813.369567 1961.911772 2299.246797 1660.955173 1631.147602 2456.851356 2159.86286 2225.756255 2114.304523 1.00712602 0.857667165 0.927922989 1.087471919 0.785579918 0.771481867 1.162013953 1.021547671 1.052713188 1 11.04596747 -7.404169639 19.9561031 1.003377154 0.944293606 0.073425027 0.117965203 10.97854805 1805.935194 0.020157384 0.023050445 3.94E-08 7.404169639 -0.059083548 AMGDS(ph)DDEYDRR ddPTM_HeLa_Curcumin_4h_R1 1 AMGDSDDEYDRR 12 1 C9JUL9 C9JUL9 SRRT 1 0 AMGDS(0.996)DDEY(0.004)DRR 77.204 0.013007 15694000 2756.9 1922 2071.4 2264.7 1982 2598.2 1973.8 1938.2 2409.7 2029.2 TRUE FALSE FALSE 2538.688456 2088.129116 2148.167906 2255.329271 1958.365944 2059.304032 2029.179516 2529.148258 2145.361939 2099.714549 1.209063612 0.994482377 1.023076164 1.074112323 0.93268199 0.980754281 0.966407323 1.204520042 1.021739807 1 11.0359775 AMGEQLLPGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AMGEQLLPGKK 11 1 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;H0YEH2 Q5T1Z4 PUM1 Pumilio homolog 1 0 1 ; AMGEQLLPGK(1)K;AMGEQLLPGK(1)K 150.94 1.47E-06 5669600 8773.3 7227 7503.3 7328.3 7265.6 9398.1 7470.2 8692.3 9811 6943.7 FALSE TRUE FALSE 8078.884047 7851.669677 7781.378899 7297.977436 7178.962465 7448.828122 7679.793707 11342.54226 8734.757846 7184.993058 1.124410835 1.092787371 1.083004373 1.01572505 0.999160668 1.036720295 1.068865849 1.578643454 1.215694681 1 12.81077105 -4.261534752 6.127340224 1.055473363 1.591705219 0.849639208 0.063839051 0.028116615 5.352068563 0.007329372 0.062433905 5.48E-05 4.261534752 0.536231855 AMGIMNSFVNDIFER ddPTM_HeLa_Curcumin_4h_R1 1 AMGIMNSFVNDIFER 15 0 P33778;P58876;P62807;P57053;O60814;Q16778;P06899;Q5QNW6;Q5QNW6-2;Q8N257;Q93079;U3KQK0;Q99877;Q99879;Q99880 P33778;P58876;P62807;Q16778;Q5QNW6;Q8N257;Q93079;U3KQK0;Q99879;Q99880 HIST1H2BB;HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST2H2BF;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BM;HIST1H2BL Histone H2B type 1-B;Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 2-F;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-M;Histone H2B type 1-L 0 0 89.663 0.0036909 720150 173.41 65.335 0 43.733 125.27 152.4 234.77 0 0 162.75 FALSE FALSE TRUE 159.6844155 70.98226627 0 43.55204443 123.7762371 120.7905221 241.3570143 0 0 168.4055504 0.948213495 0.421496002 0 0.258614068 0.734989059 0.717259745 1.43318919 0 0 1 7.395795878 -7.276100865 19.09878519 0.975545839 0.532334616 0 0.499380448 41.17152964 53631.54179 0.067531243 0.077593877 5.30E-08 7.276100865 -0.443211223 AMGY(ph)T(ph)KK ddPTM_HeLa_Curcumin_4h_R1 1 AMGYTKK 7 1 H3BPH6;Q7Z6G3-2;Q7Z6G3 H3BPH6 NECAB2 N-terminal EF-hand calcium-binding protein 2 2 0 AMGY(1)T(1)KK 52.937 0.0095441 0 1882.1 1827.4 1729.4 1551.7 1664.5 3061.6 1972.6 1619.6 2035 1641.2 TRUE FALSE FALSE 1733.129799 1985.352313 1793.493085 1545.279477 1644.651925 2426.589649 2027.945847 2113.408584 1811.765591 1698.231578 1.020549742 1.169070425 1.056094533 0.909934485 0.968449737 1.428892078 1.194151536 1.244476084 1.066854259 1 10.72981749 -5.27560033 24.99338473 1.015685426 1.279671068 0.663972272 0.085018518 319.6247311 564121.7268 0.011827076 0.0265677 5.30E-06 5.27560033 0.263985642 AMKPPGGESSNLFGS(ph)PEEATPSSRPNR ddPTM_HeLa_Curcumin_4h_R1 2 AMKPPGGESSNLFGSPEEATPSSRPNR 27 2 A6NGP5;Q9H910;Q9H910-3;H3BMV3;H3BMM8;B4E1P3 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 0 AMKPPGGES(0.003)S(0.015)NLFGS(0.973)PEEAT(0.006)PS(0.002)S(0.002)RPNR;AMKPPGGESSNLFGS(1)PEEATPSSRPNR ; 116.35 4.78E-09 32577600 1731.28 1494.54 1268.11 1847.59 2001.14 2950.4 2413.67 1055.3 1850.53 1340.23 TRUE FALSE FALSE 1594.247361 1623.721378 1315.107272 1839.945162 1977.277712 2338.453782 2481.391084 1377.056112 1647.531489 1386.802893 1.149584681 1.170837894 0.948301506 1.32675319 1.425781359 1.686219285 1.789288944 0.992971762 1.18800696 1 10.43754704 -5.9661448 2.627748172 1.073408003 1.515315077 0.420101366 0.209177057 0.169335742 2.367828219 0.029875875 0.056832735 1.08E-06 5.9661448 0.441907074 AMLDSGIYPPGS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 4 AMLDSGIYPPGSPGK 15 0 O95295 O95295 SNAPIN SNARE-associated protein Snapin 1 0 AMLDS(0.007)GIYPPGS(0.993)PGK;AMLDSGIY(0.001)PPGS(0.999)PGK;AMLDSGIYPPGS(1)PGK;AMLDSGIYPPGS(1)PGK ;;; 184.01 3.28E-05 365638000 24209.2 19555.9 21849 18978.8 19773.2 32898.1 24876.1 19773.5 24012 19748.4 TRUE FALSE FALSE 22293.01627 21246.22486 22658.74316 18900.27075 19537.4175 26074.66322 25574.05642 25802.34912 21377.94368 20434.65543 1.090941629 1.039715347 1.108839013 0.924912623 0.956092339 1.276002099 1.251504167 1.262676007 1.046161201 1 14.3187303 -5.251280366 24.9960681 1.034597967 1.26220512 0.807491591 0.053425053 259.9002287 639478.3958 0.008480806 0.021346813 5.61E-06 5.251280366 0.227607153 AMLGT(ph)HTMEVTVYHR ddPTM_HeLa_Curcumin_4h_R1 2 AMLGTHTMEVTVYHR 15 0 F8W1D1;H0YIJ2;P40967-3;P40967-4;P40967-5;P40967;P40967-2 F8W1D1 PMEL Melanocyte protein PMEL;M-alpha;M-beta 1 0 AMLGT(0.987)HT(0.013)MEVTVYHR;AMLGT(0.996)HT(0.003)MEVTVYHR ; 104.41 0.008175 232910000 12772.4 11582.1 12408.3 12627.4 13593.3 13921.4 12630.3 4087.1 12163.9 10839.5 TRUE FALSE FALSE 11761.45106 12583.20512 12868.16251 12575.15116 13431.20878 11033.94471 12984.67223 5333.237975 10829.5506 11216.17182 1.04861545 1.12188056 1.1472865 1.121162494 1.197486004 0.983753182 1.157674154 0.475495388 0.96553002 1 13.45329273 -4.255599463 24.91475625 1.060572927 0.475495122 0.84104284 0.078657051 185.4988068 791366.6447 0.011157526 0.133715311 5.55E-05 4.255599463 -0.585077805 AMNGESLDGR ddPTM_HeLa_Curcumin_4h_R1 1 AMNGESLDGR 10 0 P98179 P98179 RBM3 RNA-binding protein 3 0 0 148.94 7.09E-06 3715000 2698.5 1930.2 2229.8 2194.3 2216.4 3088.7 2297 2011.5 2761.7 2379.5 FALSE FALSE TRUE 2484.910878 2097.037887 2312.43835 2185.220568 2189.970878 2448.068803 2361.447638 2624.79709 2458.748419 2462.187448 1.00922896 0.851697091 0.939180464 0.887511863 0.889441167 0.994265812 0.959085239 1.066042755 0.998603263 1 11.26572488 AMPEDAK(ac)GQVK ddPTM_HeLa_Curcumin_4h_R1 1 AMPEDAKGQVK 11 1 A8MW92;A8MW92-4;A8MUE8 A8MW92 PHF20L1 PHD finger protein 20-like protein 1 0 1 AMPEDAK(1)GQVK 104.2 0.0063821 19716000 6138.2 5019.2 6522.9 5515 6413.5 6517.1 5931.3 5603.2 4553.3 4944 FALSE TRUE FALSE 5652.354993 5453.037283 6764.644412 5492.180391 6337.023201 5165.379997 6097.716315 7311.589886 4053.814382 5115.803632 1.104881149 1.065919976 1.322303376 1.073571385 1.238715099 1.009690826 1.191937133 1.42921629 0.792410083 1 12.32074517 -1 0.103360855 0.912212417 1.972848507 0.439883876 0.128525971 91.69095793 0.671935092 0.768031934 13.87507281 0.1 1 1.06063609 AMRQFAMDAAATAAAQR ddPTM_HeLa_Curcumin_4h_R1 1 AMRQFAMDAAATAAAQR 17 1 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4;Q9Y2J4-3 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 0 0 72.152 0.005623 0 2235.3 2153.2 1937.8 2353.7 1901.7 2145.5 1884.6 1654.1 2843.6 2251.8 FALSE FALSE TRUE 2058.373646 2339.313014 2009.616573 2343.961013 1879.02347 1700.499115 1937.476804 2158.427475 2531.664194 2330.049882 0.883403253 1.003975508 0.862477919 1.005970315 0.806430576 0.729812322 0.831517307 0.926343892 1.086527895 1 11.18614513 -5.747287436 24.99918712 0.945520483 0.817402957 0.448449766 0.077805377 168.7904068 298163.8696 0.009960791 0.019845772 1.79E-06 5.747287436 -0.128117526 KAPLNIPGT(ph)PVLEDFPQNDDEKER ddPTM_HeLa_Curcumin_4h_R1 2 KAPLNIPGTPVLEDFPQNDDEKER 24 2 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 0 KAPLNIPGT(1)PVLEDFPQNDDEKER;KAPLNIPGT(1)PVLEDFPQNDDEKER ; 84.993 6.88E-05 17234000 4006.5 3364.2 3127.4 3366.2 3244 5860.8 5960.8 6149.1 4271.8 2867.38 TRUE FALSE FALSE 3689.381297 3654.986457 3243.304195 3352.271556 3205.317419 4645.204015 6128.044005 8023.932283 3803.194228 2967.021242 1.243463055 1.231870674 1.093117956 1.129844138 1.080314955 1.565611985 2.065385957 2.70437305 1.281822379 1 11.53479954 -4.57848546 1.348597909 1.119853146 2.923785802 0.965019905 0.09631547 0.102595596 0.240420631 0.016008835 0.214614368 2.64E-05 4.57848546 1.803932656 up SPSLDNPT(ph)PFPNLGPSENPLKR ddPTM_HeLa_Curcumin_4h_R1 1 SPSLDNPTPFPNLGPSENPLKR 22 1 M0R0R8;M0R0X9;M0QXC8;M0QX56;M0R3C2;M0QYT9;M0R205;M0QZB8;M0QZB7;Q14653-3;Q14653-2;Q14653;Q14653-4 M0R0R8 IRF3 Interferon regulatory factor 3 1 0 S(0.001)PS(0.015)LDNPT(0.984)PFPNLGPSENPLKR 81.357 0.00041514 17088000 575.18 414.08 523.34 413.71 531.37 898.04 876.91 918.49 608.34 445.36 TRUE FALSE FALSE 529.6538961 449.8712301 542.7354408 411.9981776 525.0337598 711.776381 901.5137345 1198.533373 541.606624 460.8362269 1.14933216 0.976206305 1.177718697 0.894022982 1.139306611 1.544532178 1.956256219 2.600779416 1.175269201 1 8.848110323 -4.550352255 1.189796702 1.057677646 2.894141732 0.963168197 0.097548534 0.118628537 0.194101911 0.014387696 0.235435136 2.82E-05 4.550352255 1.836464086 up AMSTTSIS(ph)SPQPGK ddPTM_HeLa_Curcumin_4h_R1 1 AMSTTSISSPQPGK 14 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 0 AMSTT(0.002)S(0.08)IS(0.693)S(0.224)PQPGK 109.6 0.0035362 179090000 9919.8 8190.9 8489.1 8696 8365.2 9050.6 7827 4450.9 8422.6 6757.7 TRUE FALSE FALSE 9134.637363 8898.884898 8803.713514 8660.018256 8265.450453 7173.403539 8046.604555 5807.958921 7498.661852 6992.529572 1.306342328 1.272627424 1.259016987 1.238467162 1.182040114 1.025866743 1.150743014 0.830594831 1.072381858 1 12.77159873 -3.642790488 1.160767913 1.171703047 2.87E-11 0.505758411 0.10030103 4.963224032 1.978020141 0.019793904 10.03052745 0.00022762 3.642790488 -1.171703047 K(ac)LNVTEQEK ddPTM_HeLa_Curcumin_4h_R1 2 KLNVTEQEK 9 1 P06733;K7EM90;A0A2R8YEM5;A0A2R8Y879;A0A2R8Y6I8 P06733 ENO1 Alpha-enolase;Enolase 0 1 ; K(1)LNVTEQEK;K(1)LNVTEQEK 198.61 6.69E-22 41102000 5254 7075.3 5441.6 5691.7 12230.1 14611 12631.8 13879.8 11427.7 5079.8 FALSE TRUE FALSE 4838.140356 7686.857405 5643.270483 5668.149254 12084.26405 11580.5139 12986.21431 18111.68713 10174.1099 5256.322672 0.920442039 1.462402117 1.073615688 1.078348801 2.298995857 2.203158867 2.470589254 3.445695452 1.935594623 1 12.35983813 -4.458440649 0.503295423 0.944421809 4.652684607 0.730468561 0.407558653 0.71789791 0.138071715 0.054471741 1.506831474 3.48E-05 4.458440649 3.708262798 up AMT(ph)LSPQEEVAAGQMASSSR ddPTM_HeLa_Curcumin_4h_R1 1 AMTLSPQEEVAAGQMASSSR 20 0 A0A494BZT8;Q9Y6A5 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 0 AMT(0.724)LS(0.276)PQEEVAAGQMASSSR 115.83 0.0037676 19689000 3424 2492.7 2828.5 2778 2912.2 3782.5 2984.2 3219.3 3272.3 2780 TRUE FALSE FALSE 3152.986787 2708.157881 2933.326698 2766.505372 2877.473917 2997.966862 3067.92862 4200.84975 2913.336877 2876.604793 1.096079237 0.941442456 1.019718352 0.961725913 1.000302135 1.042189344 1.066510293 1.460349979 1.012769249 1 11.49015131 -4.253706441 3.65690304 1.028106528 1.511760077 0.905274373 0.043162363 0.075371737 1.81710397 0.007246873 0.09983628 5.58E-05 4.253706441 0.483653549 AMT(ph)MPPVSPVGAEGPVVLR ddPTM_HeLa_Curcumin_4h_R1 1 AMTMPPVSPVGAEGPVVLR 19 0 O15020;A4QPE4 O15020 SPTBN2 "Spectrin beta chain, non-erythrocytic 2" 1 0 AMT(0.984)MPPVS(0.016)PVGAEGPVVLR 92.781 0.014243 21619000 1038.9 867.46 1173.1 846.02 984.85 1518.7 1132.3 1352.7 1213 1049.4 TRUE FALSE FALSE 956.6699688 942.4393771 1216.576118 842.5193934 973.106307 1203.704501 1164.069291 1765.132003 1079.936935 1085.866572 0.881019817 0.867914532 1.120373487 0.775895875 0.896156427 1.108519713 1.072018718 1.625551471 0.994539258 1 10.08463112 -3.302179683 1.074555116 0.937275516 5.50567862 0.80830593 0.09826412 3.374721566 0.649424553 0.014343611 28.66260618 0.000498678 3.302179683 4.568403104 AMTLS(ph)PQEEVAAGQMASSSR ddPTM_HeLa_Curcumin_4h_R1 7 AMTLSPQEEVAAGQMASSSR 20 0 A0A494BZT8;Q9Y6A5 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 0 AMT(0.039)LS(0.961)PQEEVAAGQMASSSR;AMT(0.08)LS(0.92)PQEEVAAGQMASSSR;AMT(0.013)LS(0.987)PQEEVAAGQMASSSR;AMT(0.482)LS(0.518)PQEEVAAGQMASSSR;AMT(0.153)LS(0.822)PQEEVAAGQMAS(0.025)SSR;AMT(0.002)LS(0.52)PQEEVAAGQMAS(0.176)S(0.176)S(0.126)R;AMT(0.475)LS(0.525)PQEEVAAGQMASSSR ;;;;;; 178.23 2.10E-07 164886800 16305.5 14194.56 13728.26 15215.6 14741.6 20590.9 15583.7 16573.5 18035.5 14878.79 TRUE FALSE FALSE 15014.90247 15421.47452 14237.04139 15152.64188 14565.81605 16320.11523 16020.93668 21626.68385 16057.05077 15395.82685 0.975257946 1.001665885 0.924733795 0.984204488 0.946088586 1.060034995 1.04060255 1.404710775 1.042948257 1 13.91025173 -3.628856754 1.331109528 0.982750995 2.732153377 0.912749251 0.038041904 0.983274643 0.451642163 0.004564993 3.529068536 0.000235041 3.628856754 1.749402382 AMTLSPQEEVAAGQMAS(ph)SSR ddPTM_HeLa_Curcumin_4h_R1 1 AMTLSPQEEVAAGQMASSSR 20 0 A0A494BZT8;Q9Y6A5 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 0 AMT(0.004)LS(0.062)PQEEVAAGQMAS(0.826)S(0.077)S(0.031)R 65.234 0.011023 15363000 2918.9 2529.8 2977.5 2981.7 3528.3 3879.3 2875.6 3575 3134.7 3078.3 TRUE FALSE FALSE 2687.865985 2748.464639 3087.848769 2969.362515 3486.227327 3074.689451 2956.281597 4665.001043 2790.831253 3185.270696 0.843842248 0.862866896 0.969414867 0.932216693 1.094483848 0.965283565 0.928110004 1.464554033 0.876167685 1 11.63720027 -4.260793454 24.84809379 0.937842561 1.464554207 0.835337155 0.069668813 16.24710006 624857.0836 0.011158277 0.088786791 5.49E-05 4.260793454 0.526711647 AMTMPPVS(ph)PVGAEGPVVLR ddPTM_HeLa_Curcumin_4h_R1 1 AMTMPPVSPVGAEGPVVLR 19 0 O15020;A4QPE4 O15020 SPTBN2 "Spectrin beta chain, non-erythrocytic 2" 1 0 AMT(0.095)MPPVS(0.905)PVGAEGPVVLR 80.312 0.0019185 18359000 1610.7 1223.9 1614.3 1860.8 1551.5 2395.5 1792.9 2096.9 1904.6 1642.8 TRUE FALSE FALSE 1483.211395 1329.688462 1674.127378 1853.100503 1532.999376 1898.646297 1843.203949 2736.235157 1695.670145 1699.887178 0.872535198 0.782221597 0.984846171 1.090131467 0.901824189 1.116924889 1.084309578 1.609656919 0.997519228 1 10.73122328 -1.000008923 0.823010561 0.936471669 195.4933405 0.826534655 0.088818893 162.1996514 0.480727516 0.014406725 58993.8575 0.099997945 1.000008923 194.5568688 AMTVEKAS(ph)PVGDGNFR ddPTM_HeLa_Curcumin_4h_R1 1 AMTVEKASPVGDGNFR 16 1 Q86YS7;H0YFC4 Q86YS7 C2CD5 C2 domain-containing protein 5 1 0 AMT(0.316)VEKAS(0.684)PVGDGNFR 87.669 0.014342 7777100 4267.2 3264.6 3205.8 3290.2 3206.1 3746.7 3206.9 2522.2 4122.2 3122.7 TRUE FALSE FALSE 3929.446617 3546.777477 3324.609768 3276.586024 3167.869351 2969.592186 3296.876983 3291.207169 3670.004973 3231.213593 1.216090025 1.097661103 1.028904365 1.014041917 0.980396146 0.919033082 1.020321588 1.018566887 1.135797702 1 11.6578604 -6.567758262 2.492202551 1.104557416 0.987685425 0.509099519 0.056419778 0.281294189 3.538279196 0.013790451 0.020829527 2.71E-07 6.567758262 -0.116871991 AMVDSQQKS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 1 AMVDSQQKSPVK 12 1 F6QMI7;E7ETB9;Q03001;F8W9J4;Q03001-14;E9PHM6;A0A494C1D7;Q03001-8;H0YAT7;Q6P0N6;Q03001-3;Q03001-9 F6QMI7 DST Dystonin 1 0 AMVDS(0.027)QQKS(0.973)PVK 82.651 0.0096808 52669000 3065.2 2586 2479.5 2761.8 3212.9 3350.6 2348.2 2378.6 3481.6 2376.5 TRUE FALSE FALSE 2822.586186 2809.522317 2571.392451 2750.372403 3174.588266 2655.647791 2414.084172 3103.82419 3099.677191 2459.083198 1.147820532 1.142508037 1.045671189 1.118454392 1.290964156 1.079934096 0.981700893 1.262187547 1.260501146 1 11.26390483 -9.309938808 0.791042276 0.990237646 1.130589258 0 0.118935849 0.896156559 0.892798048 0.081677008 0.016717456 4.90E-10 9.309938808 0.140351611 AMVT(ph)ETMT(ph)KLR ddPTM_HeLa_Curcumin_4h_R1 1 AMVTETMTKLR 11 1 A8MVZ6;Q96G01-4;Q96G01-3;Q96G01;A0A087WYJ7 A8MVZ6 BICD1 Protein bicaudal D homolog 1 2 0 AMVT(0.996)ET(0.044)MT(0.96)KLR 89.886 0.0094765 0 65.741 145.27 243.9 168.49 87.591 146.15 187.03 183.02 210.82 212.76 TRUE FALSE FALSE 60.53753048 157.8264915 252.9391486 167.792833 86.54653453 115.8368426 192.2775584 238.8219555 187.6935734 220.1533942 0.274978865 0.716893292 1.148922321 0.76216328 0.393119238 0.526164236 0.873379941 1.084797972 0.852558164 1 7.782365277 -2.806373701 14.13580512 0.701352855 0.758158299 0 0.282918411 0 0 0.044997076 0 0.001561803 2.806373701 0.056805445 ANASNS(ph)PSSLR ddPTM_HeLa_Curcumin_4h_R1 2 ANASNSPSSLR 11 0 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 0 ANAS(0.207)NS(0.729)PS(0.058)S(0.005)LR;ANAS(0.013)NS(0.49)PS(0.49)S(0.006)LR ; 115.37 0.0048017 30242000 6910.7 6103.6 5750.8 6620.4 5750.7 6340 5303.4 2355.57 6652.6 5895.6 TRUE FALSE FALSE 6363.710803 6631.167987 5963.929707 6593.006539 5682.126658 5025.012533 5452.199131 3073.772449 5922.826424 6100.471661 1.043150621 1.086992671 0.977617804 1.08073718 0.931424154 0.823708856 0.893734031 0.503858164 0.970880082 1 12.57470507 -3.901046573 0.802732715 1.025088104 7.04E-14 0.845058687 0.063860547 1.002093961 0.315628187 0.009320868 1.046231723 0.00012559 3.901046573 -1.025088104 ANASPQK(ac)PLDLK ddPTM_HeLa_Curcumin_4h_R1 2 ANASPQKPLDLK 12 1 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 0 1 ; ANASPQK(1)PLDLK;ANASPQK(1)PLDLK 190.66 5.92E-14 7390700 5322.4 4692.7 4471.3 4680.6 4680.6 5803.5 5099.8 3349.4 5581 4269.6 FALSE TRUE FALSE 4901.126424 5098.316078 4637.010311 4661.232917 4624.786902 4599.788681 5242.886663 4370.616641 4968.778263 4417.968282 1.109362067 1.153995627 1.04957981 1.055062558 1.046813061 1.041154754 1.186718946 0.989282032 1.124674951 1 12.10916735 -9.389563618 1.147989012 1.00059054 1.083107414 0 0.066893449 0.537652569 1.281404036 0.034639411 0.00913379 4.08E-10 9.389563618 0.082516875 ANDEANQS(ph)DTSVSLSEPK ddPTM_HeLa_Curcumin_4h_R1 1 ANDEANQSDTSVSLSEPK 18 0 O95684;O95684-2;A0A087WV25 O95684 FGFR1OP FGFR1 oncogene partner 1 0 ANDEANQS(0.998)DT(0.002)S(0.001)VSLSEPK 264.92 1.44E-53 12847000 1901.3 1805.9 1650.3 1825.7 1565.2 2640 1553.8 1002.5 2136.3 1458.2 TRUE FALSE FALSE 1750.810099 1961.993949 1711.46157 1818.145737 1546.536012 2092.434241 1597.395446 1308.157635 1901.953235 1508.872341 1.160343424 1.300304801 1.13426532 1.204969889 1.024961469 1.386753659 1.058668386 0.866977013 1.260513022 1 10.55925504 -9.107236383 0.996670789 1.004523844 1.149240315 0 0.157903489 0.786202051 1.468182187 0.074764195 0.024826007 7.81E-10 9.107236383 0.144716471 ANEAGGQVGPEAPRPPET(ph)SPEMR ddPTM_HeLa_Curcumin_4h_R1 2 ANEAGGQVGPEAPRPPETSPEMR 23 1 Q8N3D4;E9PIH6 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 0 ANEAGGQVGPEAPRPPET(0.505)S(0.495)PEMR;ANEAGGQVGPEAPRPPET(0.5)S(0.5)PEMR ; 52.359 0.01063 70324000 3846.2 3366.3 3450.9 3550 3641.8 4672.3 3786.4 2573.5 3954 4129.5 TRUE FALSE FALSE 3541.769212 3657.267972 3578.79339 3535.311041 3598.373914 3703.212312 3892.636193 3358.148303 3520.256092 4272.999818 0.828871838 0.855901738 0.837536518 0.827360447 0.842118902 0.866653983 0.910984404 0.785899473 0.823837174 1 12.06103354 -9.254231481 0.805168034 1.008431444 0.845504574 0 0.06196026 0.249533753 0.267021847 0.026170271 0.00588936 5.57E-10 9.254231481 -0.16292687 ANEAGGQVGPEAPRPPETS(ph)PEMR ddPTM_HeLa_Curcumin_4h_R1 1 ANEAGGQVGPEAPRPPETSPEMR 23 1 Q8N3D4;E9PIH6 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 0 ANEAGGQVGPEAPRPPET(0.271)S(0.729)PEMR 48.255 0.014661 8421600 1338.9 1449 1137.3 1226.7 1238.8 1518.6 997.4 508.8 1492 1095 TRUE FALSE FALSE 1232.924652 1574.245103 1179.449338 1221.62424 1224.028119 1203.625242 1025.38436 663.9307778 1328.331333 1133.051168 1.088145608 1.389385711 1.040949757 1.078172173 1.080293771 1.062286749 0.904976217 0.585967162 1.172348937 1 10.1459973 -4.286751767 1.835154556 1.07485436 0.442372706 0.688390925 0.107587247 0.380933112 1.341672718 0.015777293 0.405970593 5.17E-05 4.286751767 -0.632481654 ANEFLEVGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 ANEFLEVGKK 10 1 Q14152 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 1 ANEFLEVGK(1)K 110.39 0.001767 1127300 600.59 563.13 505.29 569.99 749.57 789.55 798.71 807.99 862.08 674.61 FALSE TRUE FALSE 553.0526678 611.8044479 524.0164919 567.6315324 740.6318673 625.7884299 821.119653 1054.342431 767.5119808 698.0526473 0.792279307 0.876444564 0.750683339 0.813164357 1.060997147 0.896477411 1.176300464 1.510405319 1.099504434 1 9.447192039 -4.177645444 1.219420224 0.885614594 1.898615698 0.74031133 0.110637391 0.607555886 0.656403069 0.015605643 0.811170497 6.64E-05 4.177645444 1.013001104 ANFDKESER ddPTM_HeLa_Curcumin_4h_R1 2 ANFDKESER 9 1 Q14974;Q14974-2;J3KTM9 Q14974 KPNB1 Importin subunit beta-1 0 0 ; ; 106.68 0.0088142 30579000 7058.8 5250.3 5909.9 5445.5 5486.7 6866.7 4818.7 4568.3 6418.6 7366 FALSE FALSE TRUE 6500.088532 5704.112537 6128.926093 5422.967964 5421.274686 5442.469016 4953.899753 5961.15364 5714.495639 7621.967952 0.852809743 0.748377922 0.804113338 0.711491835 0.711269677 0.714050367 0.649950221 0.782101641 0.749740182 1 12.89594783 -7.793794981 0.446246507 1.005124901 0.694609904 0.174385272 0.084411616 0.191023172 0.097632138 0.0226484 0.016261521 1.61E-08 7.793794981 -0.310514997 ANGPHLYS(ph)SPTDSTDPR ddPTM_HeLa_Curcumin_4h_R1 1 ANGPHLYSSPTDSTDPR 17 0 C9J9G2;Q96QT6-2;Q96QT6-5;Q96QT6-3;Q96QT6;K7EPF7;Q96QT6-4 C9J9G2 PHF12 PHD finger protein 12 1 0 ANGPHLYS(0.624)S(0.315)PT(0.006)DS(0.027)T(0.027)DPR 79.467 0.004583 9935000 2051.7 1748.3 2087.8 1694.8 2053.4 3177.5 2349.4 1479.3 2526.5 2211.6 TRUE FALSE FALSE 1889.30578 1899.415262 2165.175705 1687.787367 2028.914546 2518.450682 2415.317841 1930.33176 2249.349271 2288.452935 0.8255821 0.829999705 0.946130755 0.737523303 0.886587841 1.100503595 1.055436974 0.843509486 0.98291262 1 11.16015691 -5.298874452 24.50976219 0.895670304 1.005378758 0.219075149 0.096496809 546.8409132 358030.8189 0.01497665 0.033489719 5.02E-06 5.298874452 0.109708454 ANGTSALTAQNGK(ac)AAK ddPTM_HeLa_Curcumin_4h_R1 2 ANGTSALTAQNGKAAK 16 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 1 ; ANGTSALTAQNGK(1)AAK;ANGTSALTAQNGK(1)AAK 254.1 4.31E-140 0 875.24 740.12 719.5 687.93 674.77 866.06 650.43 712.95 566.5 724.12 FALSE TRUE FALSE 805.9638305 804.0926749 746.1653029 685.0835279 666.7238085 686.4293935 668.6793153 930.325173 504.3563673 749.2831161 1.075646592 1.073149331 0.995838938 0.914318651 0.889815604 0.916114855 0.892425441 1.241620361 0.673118554 1 9.549367133 -6.532347095 7.807757344 1.039357893 0.958524142 0 0.152028583 0.214039295 87.97086492 0.015015211 0.021617092 2.94E-07 6.532347095 -0.080833751 ANK(ac)ITITNDK ddPTM_HeLa_Curcumin_4h_R1 2 ANKITITNDK 10 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6 0 1 ; ANK(1)ITITNDK;ANK(1)ITITNDK 178.46 1.18E-15 32861000 12319.7 10844.7 13254.1 12223.7 13626.6 14544.5 12251.5 11569.7 11482.3 10253.1 FALSE TRUE FALSE 11344.58275 11782.06754 13745.30861 12173.12157 13464.11169 11527.80675 12595.24412 15097.24827 10222.72042 10609.39446 1.06929597 1.110531575 1.295578994 1.147390797 1.269074474 1.086565948 1.187178416 1.423007536 0.963553618 1 13.3730547 -1.000000005 0.102243443 0.871188373 2.150689164 0.597501533 0.085206946 62.67845655 0.455235537 0.644499341 11.31272879 0.099999999 1.000000005 1.279500791 ANK(ac)ITITNDKGR ddPTM_HeLa_Curcumin_4h_R1 2 ANKITITNDKGR 12 2 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6 0 1 ; ANK(1)ITITNDKGR;ANK(1)ITITNDKGR 158.25 3.72E-06 29347000 3688.6 2752.7 2660 3095.3 2713.6 4219 2862.6 3264.9 4062 3774.5 FALSE TRUE FALSE 3396.643418 2990.631122 2758.58194 3082.492469 2681.242092 3343.931842 2942.916852 4260.35298 3616.408763 3905.663594 0.86967127 0.765716517 0.706303007 0.789236552 0.686501033 0.856175081 0.753499829 1.090814116 0.925939645 1 11.93135198 -8.19421166 0.938845863 0.97891084 0.800602672 0.224713956 0.10921687 0.406319644 0.757085909 0.032948378 0.022708073 6.39E-09 8.19421166 -0.178308169 ANK(ac)LDHVVTIIK ddPTM_HeLa_Curcumin_4h_R1 1 ANKLDHVVTIIK 12 1 E9PNR9;E9PQ98;E9PIX6;H0YDE4;E9PKG1;Q99873-2;Q99873-3;Q99873;Q99873-5 E9PNR9 PRMT1 Protein arginine N-methyltransferase 1 0 1 ANK(1)LDHVVTIIK 75.088 0.0078509 0 938.87 1025.1 869.59 843.81 1473.3 1875.1 1294.3 1100.7 1831.5 1045.3 FALSE TRUE FALSE 864.5574488 1113.705076 901.8177704 840.3185378 1455.73186 1486.183123 1330.614575 1436.298363 1630.589032 1081.624097 0.799314153 1.029660008 0.833762647 0.776904416 1.34587595 1.374029228 1.230200564 1.32790899 1.507537634 1 10.07898348 -5.753510493 24.99354884 0.899417885 1.317019662 0.322123516 0.20927717 55.69010415 175545.6593 0.014270892 0.028135821 1.76E-06 5.753510493 0.417601777 ANLPQS(ph)FQVDTSK ddPTM_HeLa_Curcumin_4h_R1 1 ANLPQSFQVDTSK 13 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 ANLPQS(0.956)FQVDT(0.017)S(0.028)K 90.685 0.011819 5337400 1816.7 1416.9 1401.3 1865.3 1772.2 1989.4 1267.6 1162.4 1890.9 1546.3 TRUE FALSE FALSE 1672.906278 1539.370522 1453.233411 1857.581883 1751.067672 1576.776015 1303.165444 1516.810409 1683.473001 1600.03381 1.04554433 0.962086246 0.908251689 1.160964144 1.094394169 0.985464185 0.814461192 0.947986474 1.052148392 1 10.64388668 -4.930114828 6.532038917 1.024207204 0.883049903 0.40357801 0.07192098 0.155370439 11.41444709 0.009870902 0.030113868 1.17E-05 4.930114828 -0.141157302 ANNSQEPS(ph)PQLASSVASTR ddPTM_HeLa_Curcumin_4h_R1 1 ANNSQEPSPQLASSVASTR 19 0 Q96HC4;Q96HC4-7;Q96HC4-4;H0Y8Y3 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 0 ANNSQEPS(0.999)PQLAS(0.001)SVASTR 236.66 5.29E-26 49777000 2433.2 2382.3 2324.6 2370.2 2446.3 4333 3285.8 1614.1 3031.5 2063.9 TRUE FALSE FALSE 2240.609652 2588.215397 2410.751721 2360.39274 2417.12947 3434.286957 3377.990705 2106.23166 2698.952034 2135.620371 1.049161022 1.211926722 1.128829708 1.105249216 1.131816077 1.608098051 1.581737443 0.986238794 1.263778933 1 11.0604395 -5.43165448 5.840101464 1.055683274 1.409740878 0.261291423 0.180934449 0.147692969 7.597447026 0.023421122 0.052802132 3.70E-06 5.43165448 0.354057604 ANNSQEPSPQLAS(ph)S(ph)VASTR ddPTM_HeLa_Curcumin_4h_R1 1 ANNSQEPSPQLASSVASTR 19 0 Q96HC4;Q96HC4-7;Q96HC4-4;H0Y8Y3 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 2 0 ANNS(0.414)QEPS(0.199)PQLAS(0.706)S(0.613)VAS(0.037)T(0.031)R 84.892 0.0078249 15139000 2058.5 1768 1489.8 1833.7 1946.9 2710.2 2481 1106.3 2030.2 1943.8 TRUE FALSE FALSE 1895.567553 1920.818042 1545.013299 1826.112635 1923.684489 2148.07397 2550.610183 1443.605777 1807.492139 2011.346905 0.942436905 0.954990925 0.768148595 0.90790536 0.956416063 1.067977863 1.268110526 0.717730876 0.898647635 1 10.97394622 -3.976303678 15.90688805 0.97380384 0.107783998 0.282291242 0.122513959 3992133.794 69941888.16 0.01652823 86858999.39 0.000105608 3.976303678 -0.866019841 ANPFGGASHAK ddPTM_HeLa_Curcumin_4h_R1 2 ANPFGGASHAK 11 0 D6RD47;P62266;D6RDJ2;D6RIX0;D6R9I7 D6RD47 RPS23 40S ribosomal protein S23 0 0 ; ; 122.18 0.00051651 10132900 11190.8 8533.7 9594.2 9066.5 9827.1 11030.3 8478.7 9218.1 9828.4 9368.9 FALSE FALSE TRUE 10305.03637 9271.315003 9949.769492 9028.985225 9709.918251 8742.491443 8716.589503 12028.65626 8750.249109 9694.468578 1.062981048 0.956351029 1.026334699 0.931354324 1.001593659 0.90180203 0.899130203 1.240775207 0.902602246 1 13.2429461 -7.258419347 24.52285716 1.02974105 0.985855324 0 0.101710959 521.4013518 4233831.05 0.014827535 0.017726237 5.52E-08 7.258419347 -0.043885726 ANPQVGVAFPHIK ddPTM_HeLa_Curcumin_4h_R1 2 ANPQVGVAFPHIK 13 0 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 0 ; ; 111.94 0.00049563 9797600 5740.5 4917 4604.9 5347.4 5303.8 5608.6 4520.2 4426.4 5371.6 5456.4 FALSE FALSE TRUE 5286.133368 5342.00357 4775.561645 5325.273876 5240.555649 4445.313138 4647.024647 5775.988983 4782.348919 5646.009494 0.936260092 0.946155612 0.845829546 0.943192512 0.928187538 0.78733717 0.823063555 1.023021479 0.847031682 1 12.46301584 -7.851274983 0.460027387 1.000053224 0.881344709 0 0.079230079 0.839938877 0.44713844 0.038724347 0.026511701 1.41E-08 7.851274983 -0.118708515 ANQEQYAEGK(ac)MR ddPTM_HeLa_Curcumin_4h_R1 1 ANQEQYAEGKMR 12 1 H0YMJ0;B3KTM8;Q9UBU8-2;H0YNE0;Q9UBU8 H0YMJ0 MORF4L1 Mortality factor 4-like protein 1 0 1 ANQEQYAEGK(1)MR 197.07 1.96E-57 0 298.73 346.4 376.24 271.93 277.38 364.85 227.55 252.48 402.72 293.59 FALSE TRUE FALSE 275.0852053 376.3412725 390.1837854 270.8048257 274.0724247 289.1759973 233.9344406 329.4599897 358.5426236 303.7922306 0.905504412 1.23881138 1.284377104 0.891414587 0.902170619 0.951887402 0.770047476 1.084491164 1.180223151 1 8.246941164 ANQISPS(ph)NSSLK ddPTM_HeLa_Curcumin_4h_R1 2 ANQISPSNSSLK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 0 ANQIS(0.028)PS(0.965)NS(0.003)S(0.003)LK;ANQIS(0.064)PS(0.909)NS(0.027)S(0.001)LK ; 164.92 0.00011955 16909600 4657.6 4259.6 5072.9 4554.9 4937.7 5866.3 4524.9 3278.5 4459.5 3852.3 TRUE FALSE FALSE 4288.946045 4627.780844 5260.906137 4536.053031 4878.821152 4649.563253 4651.856516 4278.099558 3970.304007 3986.167138 1.075957404 1.160960061 1.319790655 1.137948529 1.223937929 1.166424561 1.166999866 1.073236372 0.996020455 1 11.96078649 -7.467364827 1.951019677 1.027970121 1.183540306 0.577295053 0.061511315 0.171245275 1.275738136 0.0118592 0.013026284 3.41E-08 7.467364827 0.155570185 ANS(ph)DIISLNFR ddPTM_HeLa_Curcumin_4h_R1 2 ANSDIISLNFR 11 0 Q8TC76 Q8TC76 FAM110B Protein FAM110B 1 0 ANS(0.961)DIIS(0.039)LNFR;ANS(0.866)DIIS(0.134)LNFR ; 136.33 0.001897 6781600 2728.6 2015.25 2186.67 2262 1752.97 2489.8 1906.01 1984.7 2433.7 2154.27 TRUE FALSE FALSE 2512.628431 2189.43923 2267.709914 2252.640443 1732.066978 1973.387414 1959.487511 2589.825894 2166.729199 2229.130722 1.127178593 0.982194184 1.017306832 1.010546587 0.777014538 0.88527218 0.879036609 1.161809789 0.972006342 1 11.12226551 -5.984779999 24.87340666 1.049951429 0.916329302 0.132769369 0.101101876 228.0936622 372761.3594 0.014888026 0.026979886 1.04E-06 5.984779999 -0.133622126 ANS(ph)FVGTAQYVSPELLTEK ddPTM_HeLa_Curcumin_4h_R1 2 ANSFVGTAQYVSPELLTEK 19 0 E9PER6;Q6A1A2;O15530-4;O15530-5;O15530;O15530-2 E9PER6 PDPK1;PDPK2P Putative 3-phosphoinositide-dependent protein kinase 2;3-phosphoinositide-dependent protein kinase 1 1 0 ANS(0.997)FVGT(0.003)AQYVSPELLTEK;ANS(0.824)FVGT(0.176)AQYVSPELLTEK ; 357.92 8.06E-293 0 57367 48832 50027 54303 52131 64109 47519 50295 57208 50981 TRUE FALSE FALSE 52826.34142 53052.82049 51881.04463 54078.30857 51509.37187 50812.07074 48852.25525 65629.71397 50932.42553 52752.58596 1.001398139 1.005691371 0.983478699 1.02513095 0.976433116 0.963214785 0.926063706 1.244104204 0.965496281 1 15.6869542 -4.251824909 24.99960526 0.993652555 1.244104338 0.88392528 0.028148916 308.5757499 802344.3081 0.003705807 0.064708886 5.60E-05 4.251824909 0.250451783 ANS(ph)GGVDLDSSGEFASIEK ddPTM_HeLa_Curcumin_4h_R1 1 ANSGGVDLDSSGEFASIEK 19 0 A0A087X055;Q92766;Q92766-2;Q92766-5;Q92766-3 A0A087X055 RREB1 Ras-responsive element-binding protein 1 1 0 ANS(1)GGVDLDSSGEFASIEK 217.73 3.59E-49 0 1415.8 690.32 1176.4 1318.7 1092.8 1376.1 1252.2 811.56 1602.6 1011.1 TRUE FALSE FALSE 1303.737936 749.9881848 1219.998419 1313.243569 1079.769074 1090.681348 1287.333362 1059.000908 1426.79879 1046.23565 1.246122646 0.716844417 1.166083778 1.255208202 1.032051502 1.042481537 1.230443029 1.012201131 1.363745147 1 10.03099212 -9.823990577 1.869342145 0.999533022 1.116579973 0 0.190638125 0.824613057 5.215620443 0.115052977 0.023599292 1.50E-10 9.823990577 0.117046951 ANS(ph)PEKPPEAGAAHKPR ddPTM_HeLa_Curcumin_4h_R1 1 ANSPEKPPEAGAAHKPR 17 2 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 0 ANS(1)PEKPPEAGAAHKPR 79.471 0.0070021 4503700 1229.5 1095.3 1139.9 1253.5 1241.7 1160.3 895.7 970.72 1201.8 1004.4 TRUE FALSE FALSE 1132.183778 1189.972851 1182.145697 1248.313349 1226.893538 919.6407007 920.8309313 1266.688059 1069.965547 1039.302825 1.089368517 1.144972209 1.13744105 1.201106471 1.180496684 0.884863082 0.886008302 1.218786314 1.029503164 1 10.02140036 -3.942398455 17.82904666 1.057531668 2.934735558 0.16233109 0.106821935 75.53220761 36727.18124 0.015388282 3037.875392 0.000114183 3.942398455 1.877203891 S(ph)VSPVQDLDDDTPPSPAHSDMPYDAR ddPTM_HeLa_Curcumin_4h_R1 1 SVSPVQDLDDDTPPSPAHSDMPYDAR 26 0 G3V3A7;O00409-2;O00409 G3V3A7 FOXN3 Forkhead box protein N3 1 0 S(0.467)VS(0.467)PVQDLDDDT(0.067)PPSPAHSDMPYDAR 65.875 0.00045414 3938400 1906.9 1680.2 1807.2 2079.2 1891.2 1288.6 824.59 623.35 1958.8 2017.6 TRUE FALSE FALSE 1755.966853 1825.429001 1874.176422 2070.596821 1868.648675 1021.329834 847.7257761 813.4065454 1743.924541 2087.71145 0.841096528 0.874368439 0.897718131 0.991802206 0.895070377 0.489210247 0.40605505 0.389616365 0.83532834 1 11.02770661 -5.221961533 3.490883865 0.922407714 0.407217574 0.943710577 0.053559556 0.044888175 1.133966701 0.009489129 0.025491168 6.00E-06 5.221961533 -0.51519014 down GYYS(ph)PYSVS(ph)GSGS(ph)TAGSR ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 3 0 GYY(0.004)S(0.924)PY(0.129)S(0.189)VS(0.75)GS(0.008)GS(0.898)T(0.021)AGS(0.076)R 118.05 0.0010511 16930000 4279.4 3230.6 3773.3 4100.7 4777.5 6295.8 8539.5 8915.8 4318.4 4071.6 TRUE FALSE FALSE 3940.680974 3509.838669 3913.141817 4083.73239 4720.531433 4989.980112 8779.095387 11634.18638 3844.682324 4213.087797 0.935342714 0.833079878 0.928806141 0.969296769 1.120444591 1.184399745 2.083767491 2.761439338 0.912556896 1 12.04066227 -4.54853452 1.530402408 0.95806515 3.009932959 0.986685181 0.069489358 0.049920171 0.158028294 0.010302322 0.130399636 2.83E-05 4.54853452 2.05186781 up KVTPIDS(ph)PPVWSPEGYMALQSK ddPTM_HeLa_Curcumin_4h_R1 1 KVTPIDSPPVWSPEGYMALQSK 22 1 Q5JSZ5;Q5JSZ5-5 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 KVT(0.002)PIDS(0.998)PPVWSPEGYMALQSK 103.31 2.45E-05 20111000 3039.6 1868.7 2318 2450.6 2340.3 4251.2 4363.6 4593.3 3087.3 2752.7 TRUE FALSE FALSE 2799.012453 2030.222101 2403.907119 2440.460067 2312.393451 3369.453199 4486.030872 5993.776025 2748.630914 2848.35612 0.98267644 0.712769758 0.84396298 0.856795978 0.811834389 1.182946604 1.574954354 2.104293063 0.964988505 1 11.47591382 -4.544931075 1.658774287 0.938111211 2.209884907 0.937214503 0.10149259 0.118998103 0.463274448 0.017341202 0.202364148 2.85E-05 4.544931075 1.271773696 up ANSALT(ph)PPKPESGLTLQESNTPGLR ddPTM_HeLa_Curcumin_4h_R1 1 ANSALTPPKPESGLTLQESNTPGLR 25 1 Q9BW04-2;Q9BW04 Q9BW04-2 SARG Specifically androgen-regulated gene protein 1 0 ANS(0.079)ALT(0.851)PPKPES(0.052)GLT(0.012)LQES(0.004)NT(0.001)PGLR 71.143 0.00055752 12345000 2145.3 1632.6 2067 2063.8 1792.7 2327.2 1743.5 1750.6 2208.1 1894.5 TRUE FALSE FALSE 1975.497241 1773.714669 2143.604838 2055.260542 1771.323223 1844.512487 1792.417918 2284.349881 1965.876954 1960.333734 1.007735166 0.904802401 1.093489747 1.0484238 0.903582483 0.940917587 0.91434325 1.165286217 1.002827692 1 10.93688357 -5.803744103 24.99997847 1.005784824 0.97340268 0.024156003 0.081234957 424.5700878 250898.6672 0.011284154 0.020454359 1.57E-06 5.803744103 -0.032382144 ANSALTPPKPESGLTLQES(ph)NTPGLR ddPTM_HeLa_Curcumin_4h_R1 1 ANSALTPPKPESGLTLQESNTPGLR 25 1 Q9BW04-2;Q9BW04 Q9BW04-2 SARG Specifically androgen-regulated gene protein 1 0 ANSALT(0.044)PPKPES(0.015)GLT(0.106)LQES(0.706)NT(0.129)PGLR 64.954 0.00078505 10826000 1547.2 1555.2 1320.2 1369.5 1359.9 1422.8 1413.3 1823.8 1669.2 1150.2 TRUE FALSE FALSE 1424.737487 1689.624558 1369.127773 1363.833372 1343.684081 1127.695242 1452.953394 2379.868224 1486.092936 1190.169364 1.19708802 1.419650521 1.150363817 1.145915374 1.128985606 0.947508208 1.220795492 1.999604674 1.248639883 1 10.21695117 -4.270200744 4.054264638 1.11981482 2.069138968 0.797168691 0.126069076 0.072732443 2.534533842 0.018695326 0.19881365 5.37E-05 4.270200744 0.949324149 EERS(ph)PQTLAPVGEDAMK ddPTM_HeLa_Curcumin_4h_R1 2 EERSPQTLAPVGEDAMK 17 1 Q92797 Q92797 SYMPK Symplekin 1 0 EERS(0.972)PQT(0.028)LAPVGEDAMK;EERS(0.994)PQT(0.006)LAPVGEDAMK ; 117.48 0.00032766 40775000 8068.5 6624.8 7494.1 8182.6 8133.6 4594.3 3143.2 2230.1 6672.3 7182.7 TRUE FALSE FALSE 7429.869711 7197.418192 7771.837938 8148.742569 8036.612132 3641.390392 3231.389733 2910.047224 5940.365383 7432.29829 0.99967324 0.96839738 1.045684341 1.096396061 1.081309148 0.489941368 0.434776647 0.391540693 0.799263586 1 12.85959269 -5.220737793 5.720417858 1.013198845 0.431091792 0.910420336 0.080450306 0.023726979 2.089591575 0.006800603 0.017404794 6.02E-06 5.220737793 -0.582107053 down ANSSVGK(ac)WQDR ddPTM_HeLa_Curcumin_4h_R1 1 ANSSVGKWQDR 11 1 Q6UN15-5;Q6UN15;A0A0B4J203;Q6UN15-4 Q6UN15-5 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 0 1 ANSSVGK(1)WQDR 93.839 0.016466 1605800 822.17 873.17 549.24 590.89 527.8 868.78 714.74 398.55 623.63 622.14 FALSE TRUE FALSE 757.094377 948.642924 569.5953176 588.4450537 521.5063297 688.5852348 734.7936808 520.0660603 555.2193492 643.7593187 1.176051911 1.473598745 0.884795452 0.914076172 0.810095193 1.069631483 1.141410554 0.807857914 0.862464174 1 9.330377601 RNS(ph)VERPAEPVAGAATPSLVEQQK ddPTM_HeLa_Curcumin_4h_R1 2 RNSVERPAEPVAGAATPSLVEQQK 24 2 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 0 RNS(0.977)VERPAEPVAGAAT(0.02)PS(0.003)LVEQQK;RNS(1)VERPAEPVAGAATPSLVEQQK ; 64.749 0.00070387 162884000 3331.5 2758.2 2603.1 3199.2 3261.1 4592.2 7639.3 8745.1 3713.2 3050.2 TRUE FALSE FALSE 3067.80826 2996.606518 2699.573176 3185.962558 3222.213512 3639.725955 7853.638198 11411.44073 3305.87125 3156.194223 0.971996032 0.949436665 0.855325428 1.009431718 1.020917372 1.15320088 2.488325383 3.615569869 1.047423262 1 11.62397027 -4.540202464 1.931181859 0.972871576 3.793448297 0.993508249 0.069386381 0.02432773 0.139566436 0.010064615 0.099794236 2.88E-05 4.540202464 2.820576722 up NDS(ph)WGSFDLR ddPTM_HeLa_Curcumin_4h_R1 3 NDSWGSFDLR 10 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 NDS(0.987)WGS(0.013)FDLR;NDS(0.972)WGS(0.028)FDLR;NDS(0.943)WGS(0.057)FDLR ;; 118.73 0.0047864 8816300 3047.83 2618.93 2940.16 2630.42 3406.43 6450.43 6868.4 7618.92 3532.4 2946.7 TRUE FALSE FALSE 2806.591039 2845.298639 3049.124916 2619.536019 3365.810547 5112.538107 7061.108819 9941.893635 3144.904558 3049.097606 0.920466119 0.933160891 1.000008957 0.859118453 1.103871041 1.676738094 2.315802815 3.260601962 1.031421412 1 11.57416662 -4.52115248 1.109480775 0.949319119 3.813622101 0.991169144 0.07069887 0.068454846 0.090555011 0.010865325 0.204223155 3.01E-05 4.52115248 2.864302983 up KPS(ph)VGVPPPASPSYPR ddPTM_HeLa_Curcumin_4h_R1 1 KPSVGVPPPASPSYPR 16 1 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 1 0 KPS(1)VGVPPPASPSYPR 66.045 0.014331 11912000 1025 703.38 785.47 968.44 862.83 1718.1 2813.7 3403.2 1032 947.08 TRUE FALSE FALSE 943.8701684 764.177033 814.5802092 964.4328519 852.5413158 1361.746693 2892.644849 4440.820014 918.7921819 979.9909595 0.96314171 0.779779676 0.831211963 0.984124234 0.869948143 1.38955026 2.951705647 4.531490796 0.937551692 1 9.93662463 -4.520435226 1.706163049 0.943391172 4.921185107 0.994344632 0.088302696 0.033466469 0.136390172 0.015151543 0.183492761 3.02E-05 4.520435226 3.977793935 up RLS(ph)NLPTVDPIAVCHELYNTIR ddPTM_HeLa_Curcumin_4h_R1 2 RLSNLPTVDPIAVCHELYNTIR 22 1 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-7;Q86U86-3;Q86U86-2;Q86U86-4;Q86U86-9;Q86U86-6;C9JCJ2;C9J053;C9JQF1;C9JPI5 Q86U86-8 PBRM1 Protein polybromo-1 1 0 RLS(0.967)NLPT(0.033)VDPIAVCHELYNTIR;RLS(0.995)NLPT(0.005)VDPIAVCHELYNTIR ; 159.5 3.55E-07 50045000 1351.86 1020.41 937.73 1144.67 1061.34 2116.4 2834.2 3298.9 1399.87 1074.29 TRUE FALSE FALSE 1244.858855 1108.609694 972.4830987 1139.933659 1048.684214 1677.434783 2913.720024 4304.719424 1246.307763 1111.621498 1.119858565 0.997290621 0.874832936 1.025469246 0.943382452 1.50899815 2.621144005 3.872468671 1.121161984 1 10.11844992 -4.518955552 1.569489405 1.026501612 4.247859149 0.991427067 0.085872125 0.044458151 0.145382041 0.014063115 0.18810251 3.03E-05 4.518955552 3.221357537 up ANSTSDSVFTETPS(ph)PVLK ddPTM_HeLa_Curcumin_4h_R1 5 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 0 ANSTSDSVFTET(0.035)PS(0.964)PVLK;ANSTSDSVFTET(0.066)PS(0.934)PVLK;ANSTSDSVFTET(0.154)PS(0.846)PVLK;ANSTSDSVFTET(0.071)PS(0.929)PVLK;ANSTSDSVFTET(0.115)PS(0.885)PVLK ;;;; 228.08 1.53E-23 60509000 16819.9 13731.8 14151 12804.3 14692.1 21993.7 15979.4 15288.5 16907 13848.3 TRUE FALSE FALSE 15488.58717 14918.7156 14675.44851 12751.3192 14516.9063 17431.9587 16427.73896 19949.89327 15052.3444 14329.52739 1.080886113 1.041117072 1.024140441 0.889863207 1.013076419 1.216506185 1.146425734 1.392222697 1.050442487 1 13.80670341 -4.270525166 1.030424754 1.02750117 1.549720153 0.743345591 0.066589483 0.752177855 0.622202048 0.010793478 0.429832286 5.36E-05 4.270525166 0.522218983 ANSWQLVET(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 2 ANSWQLVETPEK 12 0 F8WF49;A0A0B4J2C2;Q9Y2H0-3;Q9Y2H0-1;Q9Y2H0 F8WF49 DLGAP4 Disks large-associated protein 4 1 0 ANS(0.016)WQLVET(0.984)PEK;ANSWQLVET(1)PEK ; 152.88 0.0011816 54884000 8949.4 8906.3 9019.3 8079.3 9777.5 10409.1 8900.9 6771.3 8152.8 8407.3 TRUE FALSE FALSE 8241.045547 9676.120886 9353.563192 8045.869997 9660.909698 8250.135325 9150.635298 8835.838199 7258.458237 8699.453049 0.94730617 1.112267729 1.075189801 0.924870788 1.110519207 0.948351038 1.051863289 1.01567744 0.834357999 1 13.08670898 ANSWQLVET(ph)PEKR ddPTM_HeLa_Curcumin_4h_R1 3 ANSWQLVETPEKR 13 1 F8WF49;A0A0B4J2C2;Q9Y2H0-3;Q9Y2H0-1;Q9Y2H0 F8WF49 DLGAP4 Disks large-associated protein 4 1 0 ANSWQLVET(1)PEKR;ANSWQLVET(1)PEKR;ANSWQLVET(1)PEKR ;; 78.166 0.012551 171603000 6320.5 5970.8 6614.8 5892.6 6449.3 7727.7 6376.6 4718.22 6937.8 6032.9 TRUE FALSE FALSE 5820.225756 6486.889347 6859.950307 5868.217983 6372.39631 6124.887911 6555.510234 6156.783558 6176.740698 6242.542826 0.932348551 1.039142146 1.098903203 0.94003648 1.020801377 0.981152726 1.050134603 0.986262126 0.989459083 1 12.6079181 -7.251523209 24.83110731 0.968053482 1.016935629 0.16232673 0.043837554 756.3460831 1893969.61 0.007626962 0.009278888 5.60E-08 7.251523209 0.048882147 ANT(ph)PDS(ph)DITEKTEDSSVPETPDNER ddPTM_HeLa_Curcumin_4h_R1 2 ANTPDSDITEKTEDSSVPETPDNER 25 1 Q9H4L7-2;Q9H4L7;D6RAY8 Q9H4L7-2 SMARCAD1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 2 0 ANT(0.974)PDS(0.885)DIT(0.114)EKT(0.021)EDS(0.003)S(0.002)VPETPDNER;ANT(0.745)PDS(0.942)DIT(0.307)EKT(0.004)EDS(0.001)SVPETPDNER ; 77.791 0.00034289 33732000 5430 4751.4 4716.5 4387.1 4723.3 5054.2 3225.2 2471 4481.5 4057.8 TRUE FALSE FALSE 5000.20977 5162.089844 4891.297639 4368.947343 4666.977732 4005.901947 3315.690432 3224.396525 3989.890662 4198.808248 1.190864044 1.229417858 1.164925224 1.040520806 1.111500563 0.954056892 0.789674173 0.767931359 0.950243599 1 12.03576419 -4.948274882 1.981958078 1.107104113 0.760179491 0.709740365 0.08153772 0.149009797 1.115334995 0.012971917 0.057125997 1.13E-05 4.948274882 -0.346924622 ANTFVAELK ddPTM_HeLa_Curcumin_4h_R1 1 ANTFVAELK 9 0 P40926;G3XAL0 P40926 MDH2 "Malate dehydrogenase, mitochondrial;Malate dehydrogenase" 0 0 107.83 0.0043294 3972600 1690 1156.2 1263 1774.4 1681.7 2024.7 1557.6 1613.8 1563.7 1513.2 FALSE FALSE TRUE 1556.234717 1256.136776 1309.807891 1767.058003 1661.646826 1604.754397 1601.302064 2105.840191 1392.166022 1565.783587 0.993901539 0.802241629 0.836519109 1.128545488 1.061223811 1.024889014 1.022684154 1.344911396 0.889117777 1 10.61266911 -1.368803686 1.044165615 0.982541838 199.9999996 0.574514332 0.096189241 516.9480411 1.311501888 0.014379926 245417.6872 0.04277562 1.368803686 199.0174577 RSPS(ph)PLGTSVR ddPTM_HeLa_Curcumin_4h_R1 1 RSPSPLGTSVR 11 1 G5E9V3;E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;E9PDY7 G5E9V3 PHLDB2 Pleckstrin homology-like domain family B member 2 1 0 RSPS(0.997)PLGT(0.003)SVR 138.2 0.0025464 24459000 3626.6 2482.9 3296.8 3034.6 2707 2012.9 1060.7 787.23 3345.1 2786.4 TRUE FALSE FALSE 3339.550783 2697.510812 3418.982308 3022.043629 2674.720793 1595.40185 1090.460387 1027.252803 2978.150899 2883.227193 1.158268343 0.935587324 1.185817863 1.048146201 0.92768298 0.55333893 0.378208277 0.356285764 1.032922729 1 11.49346881 -5.218903299 1.853580271 1.073369878 0.355069127 0.946415997 0.068283436 0.059519388 0.387838836 0.011320592 0.038553625 6.04E-06 5.218903299 -0.718300751 down DSFEMEEVQS(ph)TEGEAPHVPATYQLGLTK ddPTM_HeLa_Curcumin_4h_R1 1 DSFEMEEVQSTEGEAPHVPATYQLGLTK 28 0 E9PHV5;P28290-3;P28290;P28290-2 E9PHV5 SSFA2 Sperm-specific antigen 2 1 0 DS(0.231)FEMEEVQS(0.384)T(0.384)EGEAPHVPAT(0.001)Y(0.001)QLGLTK 46.145 0.017624 14532000 1741.2 1236 1514.3 1271.9 1335.5 813.22 279.07 239.13 1684.8 1520.8 TRUE FALSE FALSE 1603.382183 1342.834332 1570.42129 1266.637215 1319.575035 644.5490051 286.8999531 312.0396362 1499.981655 1573.647687 1.018895269 0.853325902 0.997949734 0.804905206 0.838545404 0.409589142 0.182315238 0.198290659 0.953187723 1 10.61989687 -5.198966014 1.158071716 0.993735891 0.113936299 0.951860833 0.069233901 0.073974804 0.169952016 0.010226635 0.05183438 6.32E-06 5.198966014 -0.879799592 down ANTT(ph)AFLTPLEIK ddPTM_HeLa_Curcumin_4h_R1 1 ANTTAFLTPLEIK 13 0 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 0 ANT(0.144)T(0.602)AFLT(0.254)PLEIK 152.07 0.0013555 14291000 1819.8 1555.4 1526.4 1992.8 1827.7 3290.2 2794.5 1524.6 1837.4 1264.4 TRUE FALSE FALSE 1675.76091 1689.841845 1582.969727 1984.554322 1805.905871 2607.775432 2872.906149 1989.443522 1635.841817 1308.337806 1.280831986 1.291594447 1.209909031 1.516851621 1.380305501 1.993197338 2.195844327 1.520588576 1.250320681 1 10.35351937 -5.754808036 0.842441044 1.133078192 1.957880454 0.646970845 0.207313997 0.279398651 0.364638745 0.037043776 0.13279602 1.76E-06 5.754808036 0.824802262 ANTTAFLT(ph)PLEIK ddPTM_HeLa_Curcumin_4h_R1 1 ANTTAFLTPLEIK 13 0 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 0 ANTTAFLT(1)PLEIK 175.27 0.00061852 21138000 2132.5 1589.1 1924.2 2198.8 2230.2 3580.4 3539.7 1665.1 1825.8 1255.5 TRUE FALSE FALSE 1963.710375 1726.454723 1995.512545 2189.701948 2203.606322 2837.784681 3639.014455 2172.781325 1625.514308 1299.128532 1.511559732 1.328932959 1.53603935 1.685516017 1.696218864 2.184375612 2.801119648 1.672491422 1.251234399 1 10.34332846 -5.421078549 0.253038259 0.998308223 2.855433311 0.592151114 0.308167015 2.50207913 0.217136305 0.257842769 1.443998785 3.79E-06 5.421078549 1.857125089 ANVGK(ac)LLK ddPTM_HeLa_Curcumin_4h_R1 2 ANVGKLLK 8 1 A0A087WVB9;K7ERF1;Q9UBQ5;K7ES31;K7EQM4;Q9UBQ5-2 A0A087WVB9 EIF3K Eukaryotic translation initiation factor 3 subunit K 0 1 ; ANVGK(1)LLK;ANVGK(1)LLK 112.94 0.0047824 4081200 2501.8 1888.24 2098.65 2425.5 2274.07 2964.3 2739.5 3240.4 2650.9 2801.5 FALSE TRUE FALSE 2303.77989 2051.451052 2176.427815 2415.463924 2246.9532 2349.470765 2816.362997 4228.383043 2360.102902 2898.851916 0.794721482 0.707677077 0.750789581 0.83324847 0.775118311 0.810483196 0.97154428 1.458640581 0.814150902 1 11.50126592 -4.274234732 2.967248 0.857503546 1.549704716 0.837834498 0.083725168 0.151686965 1.955344963 0.01592554 0.24473302 5.32E-05 4.274234732 0.69220117 S(ph)KTPPPPPQTAQTKR ddPTM_HeLa_Curcumin_4h_R1 2 SKTPPPPPQTAQTKR 15 2 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 S(0.89)KT(0.11)PPPPPQTAQTKR;S(0.5)KT(0.5)PPPPPQTAQTKR ; 85.837 0.0032174 30011000 8965.4 6422.5 6011.8 6528.7 4066.6 7310 3752 1809.69 11683.7 8950.6 TRUE FALSE FALSE 8255.77913 6977.632282 6234.602597 6501.685969 4018.108451 5793.823599 3857.271022 2361.45615 10402.02734 9261.632684 0.891395655 0.75339117 0.673164528 0.702002141 0.433844505 0.625572596 0.416478515 0.254971907 1.123131061 1 13.17705083 -5.196384379 0.28380952 1.02929518 2.55E-17 0.896685082 0.082730353 0.961509901 0.090279263 0.043164538 0.330725051 6.36E-06 5.196384379 -1.02929518 down EGPSCPS(ph)PGPFCR ddPTM_HeLa_Curcumin_4h_R1 2 EGPSCPSPGPFCR 13 0 Q4AC94 Q4AC94 C2CD3 C2 domain-containing protein 3 1 0 EGPS(0.363)CPS(0.637)PGPFCR;EGPS(0.002)CPS(0.998)PGPFCR ; 139.19 0.0010372 31706000 3858.3 2733.42 3256.8 3335.6 2884.2 2510.46 1510.03 1021.98 3415.6 2987.6 TRUE FALSE FALSE 3552.911484 2969.684645 3377.499873 3321.798171 2849.807799 1989.762297 1552.397378 1333.576997 3040.917225 3091.418878 1.14928181 0.96062189 1.092540353 1.074522186 0.9218446 0.643640469 0.502163388 0.431380234 0.983663924 1 11.59405343 -5.18934294 1.60589094 1.066566748 0.444319916 0.945411099 0.05668642 0.067317031 0.322607262 0.00959601 0.037076001 6.47E-06 5.18934294 -0.622246833 down AAKLS(ph)EGS(ph)QPAEEEEDQETPSR ddPTM_HeLa_Curcumin_4h_R1 2 AAKLSEGSQPAEEEEDQETPSR 22 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 2 0 AAKLS(1)EGS(1)QPAEEEEDQETPSR;AAKLS(1)EGS(1)QPAEEEEDQETPSR ; 76.606 0.00092224 76861000 11375.7 8921.4 9494.8 10621.9 8660.9 8939.4 4883.2 3874.2 12720.9 10203.5 TRUE FALSE FALSE 10475.30134 9692.526063 9846.68564 10577.94939 8557.624424 7085.267672 5020.20945 5055.425745 11325.4491 10558.07087 0.992160545 0.918020554 0.932621666 1.00188278 0.810529171 0.671075972 0.475485485 0.478820971 1.072681671 1 13.36605863 -5.182412875 1.25688686 0.987850859 0.442579472 0.952300124 0.045618126 0.060320266 0.166950293 0.005677508 0.027189861 6.57E-06 5.182412875 -0.545271387 down APAGPSLEETSVSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 APAGPSLEETSVSSPK 16 0 A0A087WXZ7;K7EIX2;Q6AI08 A0A087WXZ7 HEATR6 HEAT repeat-containing protein 6 1 0 APAGPSLEETSVS(0.139)S(0.861)PK;APAGPSLEETSVS(0.245)S(0.755)PK ; 180.48 1.54E-05 56086000 5060.2 4800.6 5521.9 5841.3 5107.4 5240.1 5342.6 3355.7 5226 4886.4 TRUE FALSE FALSE 4659.679831 5215.542473 5726.546472 5817.130248 5046.497591 4153.244192 5492.498977 4378.837482 4652.720875 5056.202036 0.921577065 1.031513859 1.132578649 1.150494028 0.998080685 0.82141579 1.08628946 0.866032934 0.920200744 1 12.3038384 -4.218522022 21.1896437 0.989726448 0.866030057 0.13758461 0.097624565 5868.208075 2896859.814 0.013880293 5.052099102 6.05E-05 4.218522022 -0.123696391 APAGQEEPGT(ph)PPSS(ph)PLSAEQLDR ddPTM_HeLa_Curcumin_4h_R1 2 APAGQEEPGTPPSSPLSAEQLDR 23 0 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 2 0 APAGQEEPGT(1)PPS(0.239)S(0.725)PLS(0.035)AEQLDR;APAGQEEPGT(1)PPS(0.36)S(0.457)PLS(0.183)AEQLDR ; 128.03 6.46E-06 7373700 3205.3 2359.2 2319.53 2499 2509.5 3022.4 2370.5 1473.23 2677.3 2607.3 TRUE FALSE FALSE 2951.597123 2563.118736 2405.493822 2488.6598 2479.575852 2395.520171 2437.00985 1922.411045 2383.606888 2697.903481 1.094033624 0.950040931 0.891615967 0.922442118 0.919075078 0.887919152 0.903297641 0.712557383 0.883503396 1 11.39762302 -6.99104744 3.161598551 1.044227822 0.879296457 0.252427298 0.079219979 0.13102812 2.715917976 0.010829316 0.014067711 1.02E-07 6.99104744 -0.164931365 SSPGSVAAS(ph)PSGGGGR ddPTM_HeLa_Curcumin_4h_R1 2 SSPGSVAASPSGGGGR 16 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 0 SSPGSVAAS(1)PSGGGGR;SSPGSVAAS(0.998)PS(0.002)GGGGR ; 239.51 4.98E-30 63187000 6305.8 4363.5 5590.3 5356.4 4522.6 4125.2 2581.6 1539.19 5506.5 4922.7 TRUE FALSE FALSE 5806.689276 4740.661497 5797.481436 5334.236636 4468.670949 3269.587019 2654.032748 2008.481945 4902.450727 5093.763459 1.139960527 0.930679553 1.138152857 1.047209333 0.877282776 0.641880418 0.521035727 0.394302162 0.962441771 1 12.31451625 -5.178225665 1.320271794 1.063779371 0.413431997 0.920306804 0.06945092 0.089991509 0.278621386 0.010710813 0.049283352 6.63E-06 5.178225665 -0.650347373 down APAPVVLGS(ph)PVVLGPPVGQAR ddPTM_HeLa_Curcumin_4h_R1 1 APAPVVLGSPVVLGPPVGQAR 21 0 A0A0C4DFM2;Q6ZN55;Q6ZN55-2 A0A0C4DFM2 ZNF574 Zinc finger protein 574 1 0 APAPVVLGS(1)PVVLGPPVGQAR 96.143 0.00028765 10151000 415.3 412.44 367.96 516.23 491.13 674.7 465.83 492.1 549.29 511.3 TRUE FALSE FALSE 382.4285668 448.0894758 381.5969213 514.093977 485.2735955 534.7596146 478.8999361 642.1390247 489.0342613 529.0676369 0.722834927 0.84694176 0.721263019 0.971698023 0.917224116 1.010758507 0.905177151 1.213718209 0.924332216 1 9.047308361 -1.000002235 0.683053203 0.862058624 37.42916146 0.510882254 0.095744451 189.3153904 1.001194577 0.020150669 10557.54294 0.099999485 1.000002235 36.56710284 APAQK(ac)APAPK ddPTM_HeLa_Curcumin_4h_R1 2 APAQKAPAPK 10 1 P50914 P50914 RPL14 60S ribosomal protein L14 0 1 ; APAQK(1)APAPK;APAQK(1)APAPK 153.08 1.55E-08 10894200 10773.4 6579.5 9258.9 7412.8 9782.9 10874.7 7559.3 6903.4 9116.7 8824.3 FALSE TRUE FALSE 9920.674022 7148.202662 9602.042979 7382.127798 9666.245307 8619.164637 7771.393613 9008.214881 8116.620819 9130.943768 1.086489444 0.782854746 1.051593704 0.80847369 1.058624996 0.943951124 0.851105188 0.986559014 0.888913679 1 13.15654827 -7.313432178 24.99993952 1.040842243 0.92935483 0.016617876 0.102063766 323.9316931 155756.8594 0.014311038 0.016365296 4.86E-08 7.313432178 -0.111487413 APAS(ph)AT(ph)S(ph)GS(ph)RK ddPTM_HeLa_Curcumin_4h_R1 1 APASATSGSRK 11 1 Q9H211 Q9H211 CDT1 DNA replication factor Cdt1 4 0 APAS(1)AT(1)S(1)GS(1)RK 65.179 0.0094356 0 465.73 346.31 415.81 393.56 408.01 481.4 398.93 380.01 355.3 471.14 TRUE FALSE FALSE 428.8669791 376.2434933 431.2202844 391.931553 403.1447472 381.5522135 410.1229021 495.8732996 316.3244789 487.5120799 0.879705338 0.771762401 0.884532511 0.803942239 0.826943093 0.782651814 0.841256902 1.017150795 0.648854648 1 8.929294157 -8.566076178 0.770161867 0.992951377 0.843471747 0 0.126266605 0.412423145 0.499485309 0.031170879 0.014399805 2.72E-09 8.566076178 -0.14947963 APASVLPAAT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 APASVLPAATPR 12 0 P13861-2;P13861;C9J830 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 1 0 APASVLPAAT(1)PR;APASVLPAAT(1)PR ; 126.32 0.0084628 43328000 3523.2 2885.6 2849.1 3577.93 3380.1 5719.4 5577.1 3164 3774.4 2470.06 TRUE FALSE FALSE 3244.335002 3135.018406 2954.690152 3563.125474 3339.794515 4533.131969 5733.578416 4128.689035 3360.357763 2555.894401 1.269354086 1.226583698 1.156029823 1.394081646 1.306702857 1.773599084 2.243276723 1.615359787 1.314748278 1 11.31961252 -5.333709341 1.761639075 1.152867163 1.956973836 0.719004695 0.181377357 0.126918977 0.751599531 0.027015418 0.085293299 4.64E-06 5.333709341 0.804106673 APDVDVNIAGPDAALKVDVKS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 APDVDVNIAGPDAALKVDVKSPK 23 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 APDVDVNIAGPDAALKVDVKS(1)PK;APDVDVNIAGPDAALKVDVKS(1)PK ; 110.61 9.65E-06 158863000 4454 3379.6 3365.8 4484.7 3624.5 4049.3 3089.8 4040.2 4714.4 4107.7 TRUE FALSE FALSE 4101.4612 3671.717565 3490.539509 4466.1435 3581.280205 3209.429535 3176.491472 5272.038381 4197.242115 4250.442269 0.964949278 0.86384365 0.821217955 1.05074795 0.842566486 0.755081314 0.747331988 1.240350544 0.987483619 1 12.05339725 -7.413120877 4.114956934 0.985159421 0.891756846 0.063497665 0.13959239 0.437544455 12.36097724 0.023267151 0.026257437 3.86E-08 7.413120877 -0.093402575 APDWVDAEECHR ddPTM_HeLa_Curcumin_4h_R1 2 APDWVDAEECHR 12 0 I3L1P5;O14964-2;O14964 I3L1P5 HGS Hepatocyte growth factor-regulated tyrosine kinase substrate 0 0 ; ; 103.14 0.006083 21564000 11178.4 10068.4 10054.8 10664.1 11027.9 12799.7 9732.2 9665.9 11994 9873.7 FALSE FALSE TRUE 10293.61784 10938.66763 10427.43973 10619.97478 10896.3995 10144.89794 10005.25934 12612.98841 10678.28821 10216.81034 1.007517758 1.07065388 1.020615964 1.039460891 1.066516763 0.992961365 0.979293831 1.234532892 1.045168487 1 13.31865724 -4.255920672 24.89263647 1.013900609 1.234532992 0.801837378 0.030879686 173.4659933 782408.5989 0.00427036 0.049668074 5.55E-05 4.255920672 0.220632383 APEAAVS(ph)EDGKSDDELLSSK ddPTM_HeLa_Curcumin_4h_R1 2 APEAAVSEDGKSDDELLSSK 20 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 APEAAVS(0.879)EDGKS(0.111)DDELLS(0.008)S(0.002)K;APEAAVS(0.752)EDGKS(0.127)DDELLS(0.098)S(0.023)K ; 50.883 0.015511 35061000 3262.9 2650.6 2552.8 2737 2884.1 2957.6 2552.1 1334.57 3312.6 2491.31 TRUE FALSE FALSE 3004.638022 2879.706053 2647.409014 2725.675019 2849.708991 2344.160421 2623.705057 1741.474249 2949.216068 2577.882837 1.165544833 1.117081821 1.026970262 1.057330838 1.105445504 0.909335516 1.017775137 0.675544375 1.144045814 1 11.33197098 -3.702664829 0.944123993 1.077758632 2.05E-17 0.751085753 0.068043315 2.174819596 0.706764416 0.011768706 3.089764341 0.000198306 3.702664829 -1.077758632 APEAAVSEDGKS(ph)DDELLSSK ddPTM_HeLa_Curcumin_4h_R1 2 APEAAVSEDGKSDDELLSSK 20 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 APEAAVS(0.005)EDGKS(0.712)DDELLS(0.242)S(0.041)K;APEAAVS(0.044)EDGKS(0.95)DDELLS(0.004)S(0.002)K ; 66.152 0.0035546 140677000 3468.1 2964.9 3145.37 3244.4 3338 2841.84 2437.77 1467.9 3838 3650.9 TRUE FALSE FALSE 3193.596225 3221.172745 3261.940179 3230.975532 3298.19653 2252.41035 2506.167265 1915.455953 3416.981002 3777.768503 0.845365782 0.852665467 0.863456873 0.855260329 0.873054166 0.596227733 0.663398846 0.507033703 0.904497192 1 11.88331858 -3.614924288 0.307156458 0.956197602 6.71E-15 0.831626858 0.06003055 3.351488841 0.169100201 0.027253745 1.2915207 0.000242703 3.614924288 -0.956197602 APEEGDAEVMQLGSS(ph)SPPPAR ddPTM_HeLa_Curcumin_4h_R1 1 APEEGDAEVMQLGSSSPPPAR 21 0 Q6NUJ5-2;Q6NUJ5 Q6NUJ5-2 PWWP2B PWWP domain-containing protein 2B 1 0 APEEGDAEVMQLGS(0.02)S(0.49)S(0.49)PPPAR 134.29 3.28E-05 5599900 747.81 779.76 689.92 870.69 820.28 1109.3 739.2 485.06 944.81 690.42 TRUE FALSE FALSE 688.6200494 847.1589799 715.4890421 867.0873155 810.4986967 879.2186756 759.9399625 632.9525611 841.1667068 714.4120436 0.963897593 1.185812848 1.001507531 1.213707584 1.134497527 1.230688485 1.063727816 0.885976891 1.177425149 1 9.480612591 -7.279784026 24.59025711 0.982951637 1.107380194 0 0.115760577 651.8441212 873768.3469 0.016351076 0.018716756 5.25E-08 7.279784026 0.124428557 APELPNTSSS(ph)PSLK ddPTM_HeLa_Curcumin_4h_R1 1 APELPNTSSSPSLK 14 0 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 0 APELPNT(0.008)S(0.004)S(0.182)S(0.719)PS(0.088)LK 99.991 0.0053097 12724000 3079.8 2169 2779 2788.8 2892.1 3686.9 3024.4 1334.2 3574.9 2522.4 TRUE FALSE FALSE 2836.03058 2356.478695 2881.992185 2777.260685 2857.613596 2922.19538 3109.256524 1740.991438 3182.742414 2610.053212 1.086579602 0.902846993 1.104189053 1.06406286 1.094848788 1.119592262 1.191261737 0.667032929 1.219416677 1 11.3498635 -4.248571936 24.87715852 1.054572964 0.667032664 0.647442032 0.090156617 846.2387233 1636038.295 0.010399707 0.256144371 5.64E-05 4.248571936 -0.387540299 APEPDLMS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 2 APEPDLMSPTR 11 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 0 APEPDLMS(0.541)PT(0.459)R;APEPDLMS(0.696)PT(0.304)R ; 110.15 0.0066586 39533000 2403.85 2182.27 2009.09 2151.13 2267.69 2666.95 2552.85 2658 2218.68 2257.4 TRUE FALSE FALSE 2213.582736 2370.895695 2083.548643 2142.229194 2240.649278 2113.794507 2624.4761 3468.411964 1975.296355 2335.844482 0.947658439 1.015005799 0.891989453 0.917111225 0.959245915 0.904938031 1.123566282 1.48486425 0.845645491 1 11.18972851 -4.33006918 2.581765908 0.962809114 1.552905169 0.900959134 0.055013204 0.072168657 0.675094623 0.006104198 0.085645609 4.68E-05 4.33006918 0.590096055 APEPPKTDK(ac)PGAAPPSTEER ddPTM_HeLa_Curcumin_4h_R1 1 APEPPKTDKPGAAPPSTEER 20 2 Q7Z3Z5;Q93074-3;Q93074;Q93074-2 Q7Z3Z5 TNRC11;MED12 Mediator of RNA polymerase II transcription subunit 12 0 1 APEPPKTDK(1)PGAAPPSTEER 79.695 0.0068063 0 876.67 1173.1 854.23 698.16 1386.9 1941.2 1173.5 1236.6 1693 954.69 FALSE TRUE FALSE 807.2806444 1274.497537 885.8885153 695.2711989 1370.362123 1538.573238 1206.425252 1613.633647 1507.282136 987.8654064 0.817196998 1.290153019 0.89677046 0.703811667 1.387195173 1.557472534 1.221244558 1.633454959 1.525797063 1 9.948170682 -5.672118576 6.927205138 0.928924291 1.448053326 0.338073333 0.255991548 0.097747927 6.402376991 0.024785373 0.049733622 2.13E-06 5.672118576 0.519129035 APES(ph)DTGDEDQDQERDTVFLK ddPTM_HeLa_Curcumin_4h_R1 2 APESDTGDEDQDQERDTVFLK 21 1 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 APES(0.817)DT(0.183)GDEDQDQERDTVFLK;APES(0.969)DT(0.031)GDEDQDQERDTVFLK ; 87.748 0.00028659 188462000 5294.6 5014.8 5554.8 5089.3 5751.4 7402.3 5395.9 4787.6 6216.7 5003.6 TRUE FALSE FALSE 4875.526823 5448.256966 5760.665774 5068.241825 5682.818311 5866.979539 5547.294432 6247.317201 5534.743563 5177.474728 0.941680468 1.05230006 1.112640057 0.978902282 1.097604259 1.13317396 1.071428587 1.206634031 1.069004458 1 12.33803289 -5.50900436 0.480667312 0.972832702 1.18913339 0.366487177 0.059074696 0.906130854 0.287138358 0.01388182 0.091499477 3.10E-06 5.50900436 0.216300688 APES(ph)PPSADPALVAGPAEEAECPPPR ddPTM_HeLa_Curcumin_4h_R1 3 APESPPSADPALVAGPAEEAECPPPR 26 0 Q6EEV4-2;Q6EEV4 Q6EEV4-2 POLR2M "DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5" 1 0 APES(0.911)PPS(0.089)ADPALVAGPAEEAECPPPR;APES(0.784)PPS(0.216)ADPALVAGPAEEAECPPPR;APES(0.984)PPS(0.016)ADPALVAGPAEEAECPPPR ;; 157.61 1.50E-09 20993300 2163.73 1970.16 2083.54 1854.05 2367.88 3174.14 2014.84 1840.75 1997.13 1806.93 TRUE FALSE FALSE 1992.468487 2140.451852 2160.757825 1846.378432 2339.644578 2515.787584 2071.370988 2401.986201 1778.049836 1869.720683 1.065650343 1.144797654 1.155658086 0.987515648 1.251333741 1.345541934 1.107850497 1.284676488 0.950970833 1 10.86860705 -6.101915639 0.314847436 0.994902418 1.30580171 0.53698364 0.086034519 1.508596668 0.273265831 0.050693022 0.171282367 7.91E-07 6.101915639 0.310899292 APET(ph)ET(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 APETETR 7 0 A0A087X1F6 A0A087X1F6 TONSL 2 0 APET(1)ET(1)R 52.299 0.0091583 0 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 APETDDSFS(ph)DVDCHSNQEDTGCK ddPTM_HeLa_Curcumin_4h_R1 1 APETDDSFSDVDCHSNQEDTGCK 23 0 Q68D20 Q68D20 PMS2CL Protein PMS2CL 1 0 APET(0.007)DDS(0.13)FS(0.853)DVDCHS(0.01)NQEDTGCK 73.341 0.00060529 5021200 1214.8 1006.3 1150.3 1357.5 1438.5 1144.5 931 750.79 1061.1 883.7 TRUE FALSE FALSE 1118.647298 1093.280088 1192.93113 1351.883025 1421.346827 907.1177988 957.1213543 979.7024148 944.6999847 914.4085092 1.223356177 1.195614517 1.304593207 1.478423496 1.554389327 0.992026856 1.046710901 1.071405619 1.033126852 1 9.836695019 -8.910193958 0.776064207 1.001717853 1.239673552 0.204121395 0.170379183 0.871219321 0.979610939 0.117802149 0.039001556 1.23E-09 8.910193958 0.237955699 APGASPGNPLS(ph)PSLSDKDR ddPTM_HeLa_Curcumin_4h_R1 2 APGASPGNPLSPSLSDKDR 19 1 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 0 APGASPGNPLS(0.955)PS(0.034)LS(0.012)DKDR;APGASPGNPLS(0.971)PS(0.021)LS(0.008)DKDR ; 130.52 6.76E-05 27336000 4429 3500.3 3765.4 4226.2 4112 4335.4 3599.9 3328.7 4958.9 4159.5 TRUE FALSE FALSE 4078.439977 3802.850335 3904.949036 4208.713104 4062.967086 3436.18917 3700.903505 4343.605307 4414.921077 4304.042315 0.947583615 0.883553194 0.907274778 0.977851237 0.943988648 0.79836324 0.859866896 1.009192054 1.025761541 1 12.07147655 -8.118225027 0.48122618 1.003306162 0.902065406 0.305343212 0.057606162 0.921674289 0.500445947 0.039123092 0.021014478 7.62E-09 8.118225027 -0.101240756 APGS(ph)PAAPR ddPTM_HeLa_Curcumin_4h_R1 2 APGSPAAPR 9 0 Q5SPY9;Q9NQX5 Q5SPY9 NPDC1 Neural proliferation differentiation and control protein 1 1 0 APGS(1)PAAPR;APGS(1)PAAPR ; 106.62 0.010242 39705000 1353.29 1478.48 1285.84 1737.81 1564.69 1728.77 915.39 493.18 2161.63 1438.35 TRUE FALSE FALSE 1246.175669 1606.273223 1333.494362 1730.619403 1546.032094 1370.203615 941.0733798 643.5483117 1924.504597 1488.332555 0.837296519 1.079243491 0.895965325 1.1627908 1.038767907 0.92063001 0.632300474 0.432395508 1.293060875 1 10.53948121 -4.619903468 2.554781369 0.957771 0.444793327 0.654744756 0.140416464 0.116215324 1.394453436 0.015075775 0.091370772 2.40E-05 4.619903468 -0.512977673 APGYPS(ph)SPVTTASGTTLR ddPTM_HeLa_Curcumin_4h_R1 2 APGYPSSPVTTASGTTLR 18 0 Q9HCK8-2;Q9HCK8;H0YJG4;H0YJA4 Q9HCK8-2 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 0 APGY(0.011)PS(0.57)S(0.403)PVT(0.012)T(0.004)ASGTTLR;APGYPS(0.578)S(0.402)PVT(0.015)T(0.005)ASGTTLR ; 122.96 0.00029893 59771000 2318.8 1719.29 1778 1490.42 1771.75 2856.4 2443 1147.6 2162.5 1728.42 TRUE FALSE FALSE 2135.264533 1867.897767 1843.894244 1484.253037 1750.623038 2263.950442 2511.544005 1497.497957 1925.27916 1788.482466 1.193897381 1.044403734 1.030982567 0.829895213 0.978831535 1.265849951 1.404287742 0.837300888 1.076487579 1 10.80452026 -5.25972986 24.99792916 1.05861103 1.192660347 0.117659637 0.160661546 257.2935314 3762297.857 0.023472609 0.056657496 5.50E-06 5.25972986 0.134049317 APGYPSS(ph)PVTTASGTTLR ddPTM_HeLa_Curcumin_4h_R1 2 APGYPSSPVTTASGTTLR 18 0 Q9HCK8-2;Q9HCK8;H0YJG4;H0YJA4 Q9HCK8-2 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 0 APGYPS(0.08)S(0.91)PVT(0.009)T(0.001)ASGTTLR;APGYPS(0.08)S(0.918)PVT(0.002)TASGTTLR ; 273.44 1.06E-54 85408000 3592.8 2688.1 2980.7 3174.9 3045.5 4164.3 4053.4 2063.9 3854.4 2721.08 TRUE FALSE FALSE 3308.426089 2920.447386 3091.167364 3161.763105 3009.184402 3300.577239 4167.127495 2693.173609 3431.581963 2815.637327 1.17501855 1.037224275 1.097857076 1.122929816 1.068740058 1.172230957 1.479994406 0.956505862 1.218758513 1 11.4592458 -13.52287875 0.160628653 0.437246013 1.198905744 0 0.145291166 85.6977864 0.917347533 15.36815579 0.241893404 3.00E-14 13.52287875 0.761659731 APIDTS(ph)DVEEK ddPTM_HeLa_Curcumin_4h_R1 2 APIDTSDVEEK 11 0 D6RIY6;Q06265-3;Q06265-4;Q06265;Q06265-2 D6RIY6 EXOSC9 Exosome complex component RRP45 1 0 APIDT(0.302)S(0.698)DVEEK;APIDT(0.015)S(0.985)DVEEK ; 165.51 0.00026837 318120000 8286 7383.9 9048 6829.3 10719.6 8466.4 7876.5 7339.7 5966.1 6479.8 TRUE FALSE FALSE 7630.154357 8022.131414 9383.326839 6801.042166 10591.77577 6710.373204 8097.493391 9577.540742 5311.633756 6704.972568 1.137984426 1.196445076 1.399457902 1.014328112 1.57968965 1.000805467 1.207684791 1.428423554 0.792193212 1 12.71101571 -7.872709036 0.626190765 1.012810452 1.267390811 0.34483443 0.183615461 0.632557628 0.566772401 0.062111924 0.045949533 1.34E-08 7.872709036 0.254580359 APIIAVTR ddPTM_HeLa_Curcumin_4h_R1 2 APIIAVTR 8 0 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BR70 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 101.64 0.011915 38854000 4027.6 2694 3567.1 2769.8 3357.7 4959.1 3876.7 3488.9 3392.9 3178.7 FALSE FALSE TRUE 3708.81121 2926.857356 3699.299864 2758.339302 3317.66162 3930.526759 3985.469768 4552.649549 3020.707359 3289.159588 1.127586276 0.889849604 1.12469455 0.838615223 1.008665445 1.194994239 1.211698509 1.384137627 0.918382729 1 11.68350329 -4.735093666 1.584396602 1.034695949 1.369202096 0.602420314 0.101345278 0.28609387 1.170573641 0.014436682 0.112119157 1.84E-05 4.735093666 0.334506147 APILIATDVASR ddPTM_HeLa_Curcumin_4h_R1 2 APILIATDVASR 12 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2;A0A0U1RQJ0;P17844-2;P17844;J3KTA4 A0A1X7SBZ2;P17844-2 DDX17;DDX5 Probable ATP-dependent RNA helicase DDX17;Probable ATP-dependent RNA helicase DDX5 0 0 ; ; 210.64 7.80E-21 7066000 1776.35 1528.13 1767.87 1297.79 1676.32 2642.3 1819.85 1668.31 1778.75 1817.45 FALSE FALSE TRUE 1635.750023 1660.214748 1833.388817 1292.420089 1656.330979 2094.257195 1870.910093 2176.970039 1583.625575 1880.606252 0.869799311 0.882808268 0.97489244 0.687235878 0.880743099 1.113607483 0.994844131 1.157589494 0.842082479 1 10.8769821 -5.261859128 24.99883672 0.913045446 1.079296751 0.497474113 0.092562971 30.50435256 1816798.615 0.014000185 0.033231598 5.47E-06 5.261859128 0.166251305 APKPDGPGGGPGGSHMGGNYGDDR ddPTM_HeLa_Curcumin_4h_R1 1 APKPDGPGGGPGGSHMGGNYGDDR 24 1 H3BPE7;P35637-2;P35637 H3BPE7 FUS RNA-binding protein FUS 0 0 51.001 0.016591 2056100 1866.5 1298.5 1685.3 1401.5 1757.5 1994.5 1474.4 1841.6 1560.6 1518 FALSE FALSE TRUE 1718.764555 1410.736554 1747.758701 1395.700964 1736.54296 1580.818217 1515.767696 2403.095362 1389.406084 1570.750387 1.094231502 0.898129051 1.112690288 0.888556817 1.105549917 1.006409567 0.964995908 1.529902766 0.884549255 1 10.61723822 -4.257100041 24.93013761 1.027274953 1.529902974 0.757912149 0.089025795 132.636379 761985.8746 0.00997947 0.104693702 5.53E-05 4.257100041 0.502628021 APKPEDIDEEDDDVPDLVENFDEASK ddPTM_HeLa_Curcumin_4h_R1 1 APKPEDIDEEDDDVPDLVENFDEASK 26 1 Q96K17-2;Q96K17 Q96K17-2 BTF3L4 Transcription factor BTF3 homolog 4 0 0 136.77 7.21E-08 4597700 1070.8 1294.7 1046.7 962.74 1433.3 1430.4 1107.7 1374.9 990.37 1090.5 FALSE FALSE TRUE 986.0450501 1406.608099 1085.491623 958.756437 1416.208834 1133.718916 1138.779081 1794.100681 881.7288888 1128.394794 0.873847571 1.246556707 0.961978581 0.849664003 1.255065019 1.004718315 1.009202707 1.589958311 0.781401061 1 10.1400562 -2.068160925 1.298855298 0.976822237 200 0.580276802 0.149006405 232.823426 1.552375081 0.020148665 136845.667 0.008547499 2.068160925 199.0231778 APKPPTDGS(ph)TSPTSTPSEDQEALGK ddPTM_HeLa_Curcumin_4h_R1 1 APKPPTDGSTSPTSTPSEDQEALGK 25 1 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;S4R3G4;F8WBN2;F6SRV7;Q8NHM5-5 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 0 APKPPT(0.009)DGS(0.348)T(0.278)S(0.348)PT(0.014)S(0.002)T(0.001)PSEDQEALGK 76.198 0.00014446 14725000 2942.2 2386.1 2286.6 2086.3 2524.5 2566.7 2163.6 1525.1 2535.1 2200.7 TRUE FALSE FALSE 2709.321765 2592.343852 2371.343407 2077.667443 2494.396986 2034.337487 2224.304793 1990.095969 2257.005873 2277.174161 1.189773629 1.138403859 1.041353555 0.912388468 1.095391397 0.893360518 0.976782905 0.873932264 0.991143282 1 11.15302892 -6.477932867 4.870453061 1.095729032 0.957430083 0.367930988 0.079610542 0.178997348 9.719831611 0.01393389 0.021110371 3.33E-07 6.477932867 -0.138298949 APKPPTDGSTS(ph)PTSTPSEDQEALGK ddPTM_HeLa_Curcumin_4h_R1 1 APKPPTDGSTSPTSTPSEDQEALGK 25 1 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;S4R3G4;F8WBN2;F6SRV7;Q8NHM5-5 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 0 APKPPT(0.003)DGS(0.03)T(0.326)S(0.425)PT(0.141)S(0.048)T(0.024)PS(0.002)EDQEALGK 54.656 0.0036763 7823300 654.78 685.21 669.2 839.6 893.32 1174.8 668.55 549.27 819.56 769.24 TRUE FALSE FALSE 602.9534721 744.4364992 694.0011407 836.1259577 882.6677424 931.1332373 687.3077137 716.7398945 729.6563184 795.9710327 0.757506803 0.935255768 0.871892459 1.050447721 1.108919428 1.169807944 0.863483325 0.900459772 0.916687026 1 9.636572118 -6.264755078 24.38110259 0.886177791 1.023420294 0.262826553 0.101599364 243.5866766 1791151.46 0.019161599 0.030034125 5.44E-07 6.264755078 0.137242503 APLALPAAGT(ph)SGT(ph)LS(ph)PRRR ddPTM_HeLa_Curcumin_4h_R1 1 APLALPAAGTSGTLSPRRR 19 2 A0A087X2C6 A0A087X2C6 KANK3 3 0 APLALPAAGT(0.956)S(0.126)GT(0.921)LS(0.998)PRRR 64.422 0.0069236 44541000 1377.5 1113.7 1083.3 1196.7 1062.7 1240.7 845.59 728.61 1360.7 986.66 TRUE FALSE FALSE 1268.469421 1209.963265 1123.448051 1191.748372 1050.027997 983.3648344 869.3149796 950.7598349 1211.434614 1020.946362 1.242444725 1.185138917 1.100398702 1.167297732 1.028484978 0.963189519 0.85147958 0.931253463 1.186580079 1 9.995691357 -5.329398024 2.003115969 1.125036751 0.894506756 0.700896992 0.067386474 0.211407214 1.629907476 0.014241752 0.042174337 4.68E-06 5.329398024 -0.230529995 APLATGEDDDDEVPDLVENFDEAS(ph)KNEAN ddPTM_HeLa_Curcumin_4h_R1 1 APLATGEDDDDEVPDLVENFDEASKNEAN 29 1 P20290;P20290-2 P20290 BTF3 Transcription factor BTF3 1 0 APLATGEDDDDEVPDLVENFDEAS(1)KNEAN 112.75 3.82E-11 4062700 758.24 642.83 670.35 706.06 722.98 1013.2 1043.9 954.61 820.97 639.56 TRUE FALSE FALSE 698.2245039 698.3933608 695.1937607 703.1385108 714.3589357 803.0508989 1073.189024 1245.666195 730.911645 661.7846624 1.055062989 1.055318143 1.050483337 1.062488375 1.079443173 1.213462542 1.621658956 1.882283264 1.104455401 1 9.370218046 -4.648662434 1.493481158 1.033260636 1.966914911 0.987944206 0.030837676 0.037370489 0.122673575 0.004131077 0.041550681 2.25E-05 4.648662434 0.933654274 APLATGEDDDDEVPDLVENFDEASK ddPTM_HeLa_Curcumin_4h_R1 2 APLATGEDDDDEVPDLVENFDEASK 25 0 P20290;P20290-2 P20290 BTF3 Transcription factor BTF3 0 0 ; ; 143.74 2.16E-08 23987000 6266.9 4651.6 5468.5 5038.3 5985.3 5439 5151.2 5181.5 4059.5 4582 FALSE FALSE TRUE 5770.868252 5053.663577 5671.167421 5017.45285 5913.929207 4310.89009 5295.728808 6761.315497 3614.183006 4741.224159 1.217168406 1.06589847 1.196139906 1.058261048 1.247342249 0.909235663 1.116953899 1.42606957 0.762288997 1 12.21104389 -9.497104393 1.206261063 0.998878407 1.151546588 0.278866474 0.150629869 0.695561381 1.789671143 0.0890162 0.020967584 3.18E-10 9.497104393 0.152668181 APLATGEDDDDEVPDLVENFDEASKNEAN ddPTM_HeLa_Curcumin_4h_R1 8 APLATGEDDDDEVPDLVENFDEASKNEAN 29 1 P20290;P20290-2 P20290 BTF3 Transcription factor BTF3 0 0 ;;;;;;; ;;;;;;; 98.967 4.48E-08 747434600 9962.63 10118.39 9318.87 10399.69 9062.1 11441.03 7822.26 9188.82 11312.16 9586.1 FALSE FALSE TRUE 9174.077323 10992.97854 9664.23552 10356.65884 8954.040376 9068.031411 8041.731563 11990.44892 10071.24435 9919.216261 0.924879253 1.108250718 0.974294265 1.044100518 0.902696356 0.914188296 0.810722476 1.208810112 1.015326623 1 13.27601042 -4.235017063 24.24627163 0.964235246 1.208810606 0.458852282 0.079067283 4133.455167 3792953.071 0.010624373 1.121542112 5.82E-05 4.235017063 0.24457536 APLK(ac)IFAQDGEGQR ddPTM_HeLa_Curcumin_4h_R1 1 APLKIFAQDGEGQR 14 1 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 1 APLK(1)IFAQDGEGQR 136.27 0.0013158 533990 64.207 0 0 0 0 0 68.416 0 69.545 0 FALSE TRUE FALSE 59.1249482 0 0 0 0 0 70.33556883 0 61.91608749 0 0 APLKPYPVS(ph)PSDKVLIQEK ddPTM_HeLa_Curcumin_4h_R1 1 APLKPYPVSPSDKVLIQEK 19 2 J3KR24;A0A0A0MSX9;P41252;Q5TCC6 J3KR24 IARS "Isoleucine--tRNA ligase, cytoplasmic" 1 0 APLKPYPVS(0.996)PS(0.004)DKVLIQEK 126.9 9.92E-05 58131000 1905.2 1582 1719.5 2078.4 1824.9 1564.5 1451.8 1604.7 1864.7 1675.9 TRUE FALSE FALSE 1754.40141 1718.741031 1783.226183 2069.800132 1803.139259 1240.005064 1492.533601 2093.965643 1660.147075 1734.1374 1.011685354 0.991121598 1.02830732 1.193561785 1.039790307 0.715055834 0.860677822 1.207496962 0.957333067 1 10.7600025 APLKPYPVSPS(ph)DKVLIQEK ddPTM_HeLa_Curcumin_4h_R1 1 APLKPYPVSPSDKVLIQEK 19 2 J3KR24;A0A0A0MSX9;P41252;Q5TCC6 J3KR24 IARS "Isoleucine--tRNA ligase, cytoplasmic" 1 0 APLKPY(0.001)PVS(0.316)PS(0.684)DKVLIQEK 78.501 0.0035239 50433000 2307.4 1643.1 1910.4 1993.3 1796.5 2204.4 1729.6 2046.9 2307.6 2201.3 TRUE FALSE FALSE 2124.766855 1785.122242 1981.201105 1985.052253 1775.077911 1747.182591 1778.127921 2670.990387 2054.462053 2277.795011 0.932817415 0.783706275 0.869789026 0.871479761 0.779296601 0.767049968 0.78063562 1.172621054 0.901952126 1 11.1534222 -7.598035671 2.287486924 0.975659276 0.851778497 0.080500459 0.115534349 0.327952152 3.549168855 0.020818547 0.021826889 2.52E-08 7.598035671 -0.12388078 APPAATNSSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 APPAATNSSKK 11 1 E9PLT2;E9PKP7;P17480-2;P17480 E9PLT2 UBTF Nucleolar transcription factor 1 0 1 APPAATNSSK(1)K 96.229 0.0048287 2122500 703.75 596.93 597.61 662.04 646.84 1057.6 877.05 467.12 841.66 837.06 FALSE TRUE FALSE 648.0474449 648.5259693 619.7579523 659.3006539 639.1268555 838.2418384 901.6576625 609.5427376 749.3320037 866.1477727 0.748195014 0.748747488 0.715533737 0.761187265 0.73789586 0.967781555 1.040997496 0.703739889 0.865131825 1 9.758469373 -3.98944261 16.93945071 0.855803866 0.474201982 0.106557667 0.115449669 55685217.79 1414699577 0.019305049 490660695.1 0.000102461 3.98944261 -0.381601884 APPAPLAASEVTNSNS(ph)AER ddPTM_HeLa_Curcumin_4h_R1 1 APPAPLAASEVTNSNSAER 19 0 Q9Y2U8 Q9Y2U8 LEMD3 Inner nuclear membrane protein Man1 1 0 APPAPLAAS(0.001)EVT(0.391)NS(0.073)NS(0.535)AER 95.988 0.0013676 4958600 229.58 376.12 410.19 387.61 258.21 450.84 293.59 122.2 408.76 228.63 TRUE FALSE FALSE 211.4085007 408.6301368 425.3920022 386.0061725 255.1310144 357.330702 301.8273452 159.4582175 363.9200507 236.5748755 0.893621947 1.727276136 1.7981284 1.63164483 1.078436642 1.510433858 1.275821638 0.674028538 1.53828698 1 7.886153056 -7.286059232 24.71435929 0.949765894 1.399299073 0.005653547 0.364584527 607.4186698 609748.5584 0.054664106 0.062525703 5.18E-08 7.286059232 0.449533179 APPEAPHPGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 APPEAPHPGKR 11 1 A0A669KBI3;F5GXF9;P51825;P51825-3;P51825-2 A0A669KBI3 AFF1 AF4/FMR2 family member 1 0 1 ; APPEAPHPGK(1)R;APPEAPHPGK(1)R 124.67 0.00032003 4709700 1759.03 1680.36 2671.3 1890.52 1647.15 1601.53 691.32 813.99 2051.17 1639.23 FALSE TRUE FALSE 1619.800919 1825.602831 2770.300728 1882.697529 1627.508812 1269.354625 710.7165786 1062.171804 1826.161783 1696.19312 0.954962557 1.076294208 1.633246058 1.109954702 0.959506788 0.748355013 0.419006875 0.626209239 1.076623741 1 10.72808472 -5.127145258 2.450264843 1.047693154 0.524723388 0.591735169 0.197289455 0.187027245 2.161589641 0.031306767 0.100459791 7.46E-06 5.127145258 -0.522969766 GPELPLVPVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 GPELPLVPVKR 11 1 Q96DI7;Q96DI7-2 Q96DI7 SNRNP40 U5 small nuclear ribonucleoprotein 40 kDa protein 0 1 GPELPLVPVK(1)R 100.48 0.0033714 4287400 856.41 937.13 722.63 760.65 683.96 956.7 1433.6 2050.8 930.52 856.74 FALSE TRUE FALSE 788.6242448 1018.131341 749.4113035 757.5026318 675.8042237 758.2696358 1473.822958 2676.079479 828.444284 886.5116512 0.889581365 1.148469216 0.84534851 0.854475664 0.76231849 0.855340857 1.662496997 3.018662502 0.934499037 1 9.791995782 -4.344321961 2.241758426 0.928365918 3.348229037 0.971382566 0.110754314 0.059772798 0.392672888 0.016638492 0.264749172 4.53E-05 4.344321961 2.419863119 up APPPPIS(ph)PTQLSDVSSPR ddPTM_HeLa_Curcumin_4h_R1 1 APPPPISPTQLSDVSSPR 18 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2 Q9P0K7-3 RAI14 Ankycorbin 1 0 APPPPIS(0.986)PT(0.013)QLS(0.001)DVSSPR 121.51 0.00033198 5380300 223.56 188.17 249.54 233.65 300.92 322.41 339.78 304.41 277.07 261.78 TRUE FALSE FALSE 205.8649901 204.4345763 258.7881719 232.6832182 297.3317255 255.5385317 349.3133123 397.2232077 246.6761142 270.8768355 0.759994814 0.754714134 0.955372103 0.859000061 1.097663907 0.943375358 1.289565096 1.466434761 0.910657841 1 8.081493214 -4.260892714 0.837546525 0.878052296 1.844975883 0.802670888 0.095443805 0.876972032 0.444167147 0.018360884 0.782902768 5.48E-05 4.260892714 0.966923588 APPQTHLPS(ph)GASSGTGSASATHGGGSPPGTR ddPTM_HeLa_Curcumin_4h_R1 1 APPQTHLPSGASSGTGSASATHGGGSPPGTR 31 0 P46379-3;P46379;P46379-2;P46379-5;A0A0G2JK23;A0A024RCR6;A0A0G2JL47;P46379-4;A0A0G2JJR8;A0A1B0GX79;F6X9W3;F6VEM6;F6U341;F6TC96;F6S6P2;X6REW1;A0A0G2JJM1;F6XTU0;F6U1F2;F6UR09;F6WML8 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 0 APPQTHLPS(0.619)GAS(0.223)S(0.154)GT(0.001)GS(0.002)ASAT(0.001)HGGGSPPGTR 88.186 4.30E-07 8321500 891.72 635.89 531.56 782.75 1554.6 3536.6 1067.9 1053.5 1354.2 718.18 TRUE FALSE FALSE 821.1394211 690.8534981 551.2600812 779.5111879 1536.06241 2803.069294 1097.8624 1374.7073 1205.647648 743.1367015 1.10496416 0.929645241 0.741801717 1.048947234 2.06699845 3.77194302 1.477335728 1.849871359 1.622376671 1 9.537483812 -5.710612286 4.587034992 1.013116407 2.368048149 0.504472795 0.592859421 0.111648306 4.933755528 0.079246992 0.159444868 1.95E-06 5.710612286 1.354931742 APPQTHLPSGASSGTGSASAT(ph)HGGGSPPGTR ddPTM_HeLa_Curcumin_4h_R1 1 APPQTHLPSGASSGTGSASATHGGGSPPGTR 31 0 P46379-3;P46379;P46379-2;P46379-5;A0A0G2JK23;A0A024RCR6;A0A0G2JL47;P46379-4;A0A0G2JJR8;A0A1B0GX79;F6X9W3;F6VEM6;F6U341;F6TC96;F6S6P2;X6REW1;A0A0G2JJM1;F6XTU0;F6U1F2;F6UR09;F6WML8 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 0 APPQTHLPS(0.007)GAS(0.01)S(0.01)GT(0.006)GS(0.115)AS(0.01)AT(0.479)HGGGS(0.334)PPGT(0.029)R 94.534 7.86E-08 0 319.3 152.38 175.03 196.99 353.53 758.89 246.16 142.19 259.93 219.77 TRUE FALSE FALSE 294.0270681 165.5510482 181.5167658 196.1749076 349.3143856 601.4876595 253.0665871 185.5430764 231.4163293 227.4069911 1.292955272 0.727994541 0.798202223 0.862659967 1.536075843 2.644983149 1.112835563 0.81590753 1.017630672 1 7.829132797 -5.706751171 8.621165854 1.061931256 1.579800192 0.243709635 0.470924461 0.364185784 52.41331805 0.070119702 0.14019529 1.96E-06 5.706751171 0.517868936 APQCLGK(ac)FIEIAAR ddPTM_HeLa_Curcumin_4h_R1 1 APQCLGKFIEIAAR 14 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PRZ7;A0A1W2PQD4;A0A1W2PQ74;A0A1W2PPE9 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 1 APQCLGK(1)FIEIAAR 100.73 0.0061593 2742400 68.051 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 62.66469154 0 0 0 0 0 0 0 0 0 0 APQCLLY(ph)Y(ph)EPYYS(ph)RVVLES(ph)GIT(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 1 APQCLLYYEPYYSRVVLESGITPGK 25 1 A0A0A0MS02 A0A0A0MS02 TRGV1 5 0 APQCLLY(0.593)Y(0.593)EPY(0.593)Y(0.593)S(0.629)RVVLES(1)GIT(1)PGK 40.723 0.0079141 0 1766.5 1234.5 1478.5 1306.5 1824.8 2097.5 1612.1 1658.3 1901.7 1757.7 TRUE FALSE FALSE 1626.679661 1341.204679 1533.294511 1301.094049 1803.040452 1662.454856 1657.331187 2163.908036 1693.088268 1818.779944 0.89437959 0.737419985 0.843034648 0.715366393 0.991346126 0.914049477 0.911232386 1.189758026 0.930892312 1 10.82875529 -4.261434241 10.07673035 0.910601617 1.190405342 0.469865685 0.093740315 0.060000291 206.326542 0.014621822 0.113348812 5.48E-05 4.261434241 0.279803725 APQTS(ph)SS(ph)PPPVRR ddPTM_HeLa_Curcumin_4h_R1 1 APQTSSSPPPVRR 13 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 0 APQT(0.397)S(0.588)S(0.085)S(0.931)PPPVRR 89.136 0.020385 25543000 3573.7 3116.9 3359.9 3389.3 3449.5 3939.6 3120.8 1993.5 3176.6 3019.7 TRUE FALSE FALSE 3290.837874 3386.310947 3484.42085 3375.275975 3408.366965 3122.482552 3208.361249 2601.308973 2828.134927 3124.63435 1.053191351 1.08374631 1.115145153 1.080214706 1.090805062 0.999311344 1.026795743 0.832516282 0.905109082 1 11.60947166 -4.004368857 1.843952973 1.043919464 0.622575872 0.533278336 0.057994666 0.96342806 1.832752631 0.00662663 0.87675908 9.90E-05 4.004368857 -0.421343592 APQTSS(ph)SPPPVR ddPTM_HeLa_Curcumin_4h_R1 1 APQTSSSPPPVR 12 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 APQT(0.021)S(0.17)S(0.572)S(0.236)PPPVR 119.21 0.0028482 0 2405.6 2026.2 2041.4 2217 2012.8 2244.3 1928.9 1886.5 2378.3 2321.4 TRUE FALSE FALSE 2215.194222 2201.335699 2117.05608 2207.826641 1988.798675 1778.806882 1983.019743 2461.685166 2117.40644 2402.068477 0.922202778 0.916433366 0.881347097 0.919135596 0.827952531 0.740531296 0.825546716 1.024818896 0.881492955 1 11.23006156 -7.70470425 0.480969265 0.995920964 0.852544512 0.053711167 0.077332329 0.704622452 0.408473341 0.036908196 0.029255077 1.97E-08 7.70470425 -0.143376453 APQTSSS(ph)PPPVR ddPTM_HeLa_Curcumin_4h_R1 6 APQTSSSPPPVR 12 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 APQT(0.01)S(0.004)S(0.033)S(0.953)PPPVR;APQT(0.009)S(0.043)S(0.086)S(0.862)PPPVR;APQT(0.009)S(0.003)S(0.03)S(0.958)PPPVR;APQT(0.049)S(0.31)S(0.154)S(0.487)PPPVR;APQT(0.017)S(0.007)S(0.025)S(0.951)PPPVR;APQT(0.009)S(0.009)S(0.078)S(0.905)PPPVR ;;;;; 167.03 0.000124 3515723000 23580.3 20627 20415.5 22012 22243.1 25821.1 20747.8 20162.2 23998.8 20009.6 TRUE FALSE FALSE 21713.89437 22409.90597 21172.11639 21920.92018 21977.86556 20465.5128 21329.92743 26309.56196 21366.19168 20704.93211 1.048730527 1.082346266 1.022563913 1.058729392 1.061479721 0.988436605 1.030185818 1.270690569 1.031937297 1 14.33768685 -4.261412065 23.68445846 1.030365509 1.270690554 0.867024283 0.027486982 0.293100549 251154.1568 0.00426926 0.032796372 5.48E-05 4.261412065 0.240325045 APQVVAEAAK(ac)TAK ddPTM_HeLa_Curcumin_4h_R1 1 APQVVAEAAKTAK 13 1 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 0 1 APQVVAEAAK(1)TAK 158.86 8.18E-05 5829100 1826.5 1395.3 1365.6 1540.4 1380.4 1952.5 1645.1 1239.4 1781.5 1456.1 FALSE TRUE FALSE 1681.930598 1515.903515 1416.210337 1534.026233 1363.939632 1547.529491 1691.257078 1617.287355 1586.073907 1506.699367 1.11630139 1.006108815 0.939942213 1.018136907 0.90525002 1.027099052 1.122491398 1.073397514 1.052681074 1 10.55717587 APRPFGSVSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 APRPFGSVSSPK 12 1 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 0 APRPFGSVS(0.153)S(0.847)PK 69.456 0.016543 264930000 4504.5 4062.4 4163.2 4393.3 4655.6 7253 6197.1 3041.1 5204.1 4185 TRUE FALSE FALSE 4147.964072 4413.535754 4317.491854 4375.121689 4600.085011 5748.646042 6370.973947 3968.31739 4633.22325 4330.428438 0.957864593 1.019191477 0.997012632 1.010320746 1.062270183 1.327500529 1.471210999 0.916379856 1.069922599 1 12.08029405 -5.427577929 3.948532669 0.987358402 1.259952343 0.361910555 0.133222506 0.143703012 4.019839801 0.017165576 0.03973326 3.74E-06 5.427577929 0.27259394 APRPSAPS(ph)PPPR ddPTM_HeLa_Curcumin_4h_R1 2 APRPSAPSPPPR 12 1 Q8IV50 Q8IV50 LYSMD2 LysM and putative peptidoglycan-binding domain-containing protein 2 1 0 APRPS(0.013)APS(0.987)PPPR;APRPSAPS(1)PPPR ; 139.78 0.011713 23880900 1972.29 2034.63 1901.43 1984.29 1801.22 2767.29 1938.9 1869.83 2110.86 2263.4 TRUE FALSE FALSE 1816.181165 2210.494351 1971.898668 1976.079534 1779.741628 2193.32286 1993.300316 2439.932559 1879.303939 2342.052982 0.775465448 0.943827645 0.841953057 0.843738186 0.759906647 0.936495834 0.851091043 1.041792213 0.802417347 1 11.193558 -4.25479162 23.84490383 0.880255611 1.041792355 0.315071676 0.075311298 492.2043704 1765398.09 0.012668815 0.159144209 5.56E-05 4.25479162 0.161536744 VGS(ph)PQPSSSGGEK ddPTM_HeLa_Curcumin_4h_R1 2 VGSPQPSSSGGEK 13 0 V9GYB6;O94761 V9GYB6 RECQL4 ATP-dependent DNA helicase Q4 1 0 VGS(0.979)PQPS(0.006)S(0.012)S(0.004)GGEK;VGS(0.86)PQPS(0.105)S(0.032)S(0.003)GGEK ; 146.84 0.00069206 50496000 13046.1 9830.5 11379.2 11028 9817.1 8511.8 8321.4 3619.4 12028.4 10752.6 TRUE FALSE FALSE 12013.48742 10680.20462 11800.92316 10982.36906 9700.037494 6746.356732 8554.876088 4722.938398 10708.91461 11126.25205 1.079742519 0.959910361 1.06063777 0.987068153 0.871815365 0.606345848 0.768891092 0.424486015 0.962490744 1 13.44168007 -5.177749603 0.927277384 1.037964405 0.498352189 0.828789457 0.083348368 0.202470995 0.268646442 0.012259432 0.079658391 6.64E-06 5.177749603 -0.539612216 down LLKPGEEPSEYT(ph)DEEDTKDHNKQD ddPTM_HeLa_Curcumin_4h_R1 2 LLKPGEEPSEYTDEEDTKDHNKQD 24 3 U3KPU8;U3KQM0;O15173;O15173-2 U3KPU8 PGRMC2 Membrane-associated progesterone receptor component 2 1 0 LLKPGEEPS(0.018)EY(0.068)T(0.794)DEEDT(0.12)KDHNKQD;LLKPGEEPS(0.095)EY(0.089)T(0.734)DEEDT(0.083)KDHNKQD ; 71.042 0.0002856 183022000 5973.77 5285.44 5487.34 8320.93 5119.81 5184.96 2657.27 1840.16 9243.6 7342.83 TRUE FALSE FALSE 5500.939801 5742.289882 5690.705648 8286.500196 5058.75961 4109.540849 2731.825845 2401.216313 8229.600206 7597.992796 0.723999081 0.75576406 0.748974867 1.090617011 0.665802107 0.540871907 0.359545727 0.316032981 1.083128193 1 12.89140263 -5.176547305 1.805012212 0.860503983 0.333488542 0.731131102 0.134933952 0.152882658 0.939825906 0.020511546 0.074062281 6.66E-06 5.176547305 -0.527015442 down RS(ph)PVPAQIAITVPK ddPTM_HeLa_Curcumin_4h_R1 3 RSPVPAQIAITVPK 14 1 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 0 RS(1)PVPAQIAITVPK;RS(1)PVPAQIAITVPK;RS(1)PVPAQIAITVPK ;; 154.49 0.00019319 623870000 24993.2 21136.6 22762.6 22644.4 19738 15534 8075.3 5765.12 22158.7 20120.4 TRUE FALSE FALSE 23014.96185 22963.55352 23606.20198 22550.70347 19502.63724 12312.0733 8301.871184 7522.878549 19727.94605 20819.5824 1.105447814 1.102978584 1.133846084 1.083148693 0.936744881 0.591369849 0.398753012 0.361336669 0.947566847 1 14.34565351 -5.174054977 1.878953797 1.065082897 0.367283991 0.965827589 0.052625405 0.042907804 0.287074439 0.007890237 0.027847188 6.70E-06 5.174054977 -0.697798906 down APS(ph)DSSLGTPSDGRPELR ddPTM_HeLa_Curcumin_4h_R1 4 APSDSSLGTPSDGRPELR 18 1 M0R0F9;W4VSQ9;Q15642-4;Q15642-2;Q15642-3;Q15642;M0R2H7;Q15642-5 M0R0F9 TRIP10 Cdc42-interacting protein 4 1 0 APS(0.871)DS(0.055)S(0.074)LGTPSDGRPELR;APS(0.946)DS(0.043)S(0.011)LGT(0.001)PSDGRPELR;APS(0.969)DS(0.023)S(0.008)LGTPSDGRPELR;APS(0.985)DS(0.008)S(0.008)LGTPSDGRPELR ;;; 139.38 0.00013774 1444722000 6988.2 5273.4 5706.6 6259.2 6680.1 9883.6 6708.4 4050.95 7427.7 6621.4 TRUE FALSE FALSE 6435.076596 5729.209198 5918.091616 6233.301089 6600.44417 7833.629949 6896.619649 5286.066007 6612.899893 6851.493157 0.939222509 0.836198631 0.863766697 0.90977265 0.9633585 1.143346387 1.006586373 0.771520293 0.965176457 1 12.74220272 -4.253217502 24.3347933 0.963192263 0.771520155 0.324632774 0.080708343 698.8164147 2068259.916 0.011995129 0.176956042 5.58E-05 4.253217502 -0.191672108 APS(ph)EIDPR ddPTM_HeLa_Curcumin_4h_R1 1 APSEIDPR 8 0 O95801 O95801 TTC4 Tetratricopeptide repeat protein 4 1 0 APS(1)EIDPR 96.034 0.017374 75675000 5783.8 5075.9 4994.2 5722.3 5368.3 6925.6 5462.1 4923.6 6394.3 5315.4 TRUE FALSE FALSE 5326.006127 5514.638178 5179.289445 5698.622639 5304.286529 5489.152492 5615.351826 6424.782975 5692.861288 5500.109754 0.968345427 1.002641479 0.941670199 1.036092531 0.964396488 0.99800781 1.020952686 1.168119049 1.035045034 1 12.42524469 -4.171185883 2.007931945 0.985550366 1.251821919 0.763228427 0.028822903 0.267366879 0.939517559 0.003211294 0.140815883 6.74E-05 4.171185883 0.266271553 APS(ph)IDGKEELDLAEK ddPTM_HeLa_Curcumin_4h_R1 1 APSIDGKEELDLAEK 15 1 Q9H0E9-4;Q9H0E9-2;H7C128;H7C179;H7C127;B5MCW3;Q9H0E9;H0YAH7;H0YA84;Q9H0E9-3 Q9H0E9-4;Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 0 APS(1)IDGKEELDLAEK 154.51 0.0037185 13579000 2891.2 2362.5 2443.1 2530.3 2914.7 2993 2538.5 2354.6 2543 2386.8 TRUE FALSE FALSE 2662.358469 2566.703973 2533.643435 2519.830289 2879.944106 2372.218062 2609.723478 3072.506701 2264.039262 2469.741122 1.077990906 1.03926033 1.025874094 1.02028114 1.16609149 0.960512841 1.056678959 1.244060227 0.916711165 1 11.27014411 -4.268511876 4.96126381 1.039954853 1.253387376 0.497890926 0.06409318 0.085895879 6.423931872 0.006987839 0.062184655 5.39E-05 4.268511876 0.213432523 APS(ph)LTDLVK ddPTM_HeLa_Curcumin_4h_R1 1 APSLTDLVK 9 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 0 APS(0.748)LT(0.252)DLVK 94.767 0.016198 71856000 3321.7 1895.7 2822.5 3397 2953.7 5426.5 4006.5 2366.4 3696.7 2750.8 TRUE FALSE FALSE 3058.78394 2059.555861 2927.104333 3382.944114 2918.479057 4300.982731 4118.911607 3087.904466 3291.181259 2846.390095 1.074618671 0.723567674 1.028356703 1.188503333 1.025326452 1.511030669 1.447065044 1.084849358 1.156265005 1 11.47491768 -5.279700702 24.01823165 1.022708178 1.357590007 0.467189206 0.156204008 278.6361123 366476.4277 0.021050647 0.04717007 5.25E-06 5.279700702 0.334881829 APS(ph)LTNDEVEEFR ddPTM_HeLa_Curcumin_4h_R1 1 APSLTNDEVEEFR 13 0 A0A3B3ISR7;E9PIF2;Q13206 A0A3B3ISR7 DDX10 Probable ATP-dependent RNA helicase DDX10 1 0 APS(0.988)LT(0.012)NDEVEEFR 172.26 0.00020267 6320200 287.94 223.02 272.66 187.87 250.75 356.09 270.37 233.6 323.57 218.2 TRUE FALSE FALSE 265.1492452 242.296855 282.7650195 187.0926437 247.75997 282.23292 277.9558545 304.8235646 288.0751805 225.7824338 1.174357282 1.073143074 1.252378295 0.828641275 1.097339443 1.250021604 1.231078299 1.35007653 1.275897224 1 7.818789436 -5.239527761 4.149730426 1.077404831 1.277347991 0.288942988 0.124467892 0.17262526 7.057515404 0.016100253 0.04148735 5.76E-06 5.239527761 0.19994316 APS(ph)PDPDLVQR ddPTM_HeLa_Curcumin_4h_R1 1 APSPDPDLVQR 11 0 A0A087WVB5;Q75MD7;A0A2R8Y8C6;Q8WXX7-2;Q8WXX7 A0A087WVB5 AUTS2 Autism susceptibility gene 2 protein 1 0 APS(1)PDPDLVQR 145.81 0.00094784 14325000 1270.5 1274 1222.9 1284.2 1082.2 1513.3 1268.7 931.58 1314.7 1177.3 TRUE FALSE FALSE 1169.938584 1384.118883 1268.22175 1278.886321 1069.295472 1199.424522 1304.296307 1215.614454 1170.480699 1218.211087 0.960374271 1.136189694 1.041052542 1.049806831 0.877758775 0.984578563 1.070665274 0.997868486 0.960819279 1 10.25054842 APS(ph)PEPAAPR ddPTM_HeLa_Curcumin_4h_R1 2 APSPEPAAPR 10 0 P20749 P20749 BCL3 B-cell lymphoma 3 protein 1 0 APS(1)PEPAAPR;APS(1)PEPAAPR ; 131.42 0.0027192 221390000 5819 4532.5 4896.6 4916.7 6137.4 7009.6 5035.7 3088.8 6008.8 5027.3 TRUE FALSE FALSE 5358.42001 4924.269104 5078.072303 4896.355998 6064.215513 5555.729946 5176.988189 4030.560901 5349.649673 5201.998301 1.030069543 0.946611056 0.976177232 0.941245213 1.165747308 1.067999185 0.995192211 0.774810115 1.028383587 1 12.34485021 -4.267091533 4.566290927 1.015906799 0.760444768 0.584419512 0.061450692 0.101471664 5.479228203 0.008489259 0.082228343 5.41E-05 4.267091533 -0.255462032 ISSLPVSRPIS(ph)PSPSAILER ddPTM_HeLa_Curcumin_4h_R1 1 ISSLPVSRPISPSPSAILER 20 1 Q5T5P2;Q5T5P2-3;Q5T5P2-7;Q5T5P2-8;Q5T5P2-6;Q5T5P2-9;Q5T5P2-2;Q5T5P2-10;Q5T5P2-4;Q5T5P0;Q5T5P1 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 0 ISSLPVS(0.002)RPIS(0.993)PS(0.004)PS(0.001)AILER 88.04 0.00065426 169090000 1428.4 1162.5 1241.6 1161.6 888.92 1007.7 582 326.9 1355.2 1314.1 TRUE FALSE FALSE 1315.340633 1262.98132 1287.614788 1156.793607 878.3202096 798.6916609 598.3293536 426.5703051 1206.537951 1359.764877 0.967329466 0.928823314 0.946939291 0.850730613 0.645935356 0.587374828 0.440024127 0.313708872 0.88731366 1 10.4091415 -5.162748766 0.665775355 0.990109744 0.221003623 0.964835356 0.043282473 0.100377401 0.057655432 0.005278318 0.046763126 6.87E-06 5.162748766 -0.769106121 down APS(ph)PPEAALQPAPTEPR ddPTM_HeLa_Curcumin_4h_R1 2 APSPPEAALQPAPTEPR 17 0 Q9NVR5-2;Q9NVR5 Q9NVR5-2 DNAAF2 Protein kintoun 1 0 APS(1)PPEAALQPAPTEPR;APS(0.997)PPEAALQPAPT(0.003)EPR ; 127.49 0.00033877 17768200 1137.97 899.35 793.95 1037.72 1048.52 793.15 660.89 696.5 1314.23 1016.8 TRUE FALSE FALSE 1047.898474 977.0858066 823.3744854 1033.42619 1036.017084 628.6417494 679.4327947 908.8596437 1170.062257 1052.133724 0.995974608 0.928670742 0.78257589 0.982219432 0.984681947 0.597492253 0.645766578 0.863825218 1.112085118 1 10.03910236 -5.667336236 0.66428328 0.995570964 0.688003632 0.463812454 0.115558023 0.612449355 0.446522287 0.021648341 0.101709382 2.15E-06 5.667336236 -0.307567332 APS(ph)PPLSQVFQTR ddPTM_HeLa_Curcumin_4h_R1 1 APSPPLSQVFQTR 13 0 B1AKL4;Q9NRA8;Q9NRA8-3;Q9NRA8-2 B1AKL4 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 0 APS(0.999)PPLS(0.001)QVFQTR 120.21 0.0024879 107260000 679.95 358.04 680.63 429.71 457.92 526.05 448.14 257.79 406.61 524.33 TRUE FALSE FALSE 626.13124 388.9873822 705.8547465 427.9319739 452.4596031 416.9413002 460.7136023 336.3889843 362.0059003 542.5504285 1.154051692 0.716960787 1.300993805 0.78874138 0.833949398 0.768483957 0.849162729 0.620014227 0.667229959 1 9.083613428 -6.134946614 10.62466093 1.057778311 0.77848238 0.128837206 0.193323581 0.2867054 23.32272382 0.021241018 0.035244291 7.33E-07 6.134946614 -0.279295931 APS(ph)PPPTASNSSNSQSEK ddPTM_HeLa_Curcumin_4h_R1 1 APSPPPTASNSSNSQSEK 18 0 Q8N108-17;Q8N108;Q8N108-13;Q8N108-12;Q8N108-19;Q8N108-16;Q8N108-14;Q8N108-18;Q8N108-15 Q8N108-17 MIER1 Mesoderm induction early response protein 1 1 0 APS(0.977)PPPT(0.022)AS(0.001)NSSNSQSEK 144.3 2.38E-06 0 1125.5 1254.7 901 769.92 1268.6 1060.3 804.34 458.78 743.3 786.77 TRUE FALSE FALSE 1036.415487 1363.150677 934.3918526 766.734275 1253.472774 840.381828 826.9076156 598.65991 661.7618496 814.1101989 1.273065352 1.674405601 1.147746157 0.941806498 1.5396844 1.03227036 1.015719514 0.735354883 0.8128652 1 9.669080282 -4.399127324 1.720647073 1.184333238 0.661340728 0.235144929 0.249615025 0.763029008 2.715325467 0.033703788 0.595788553 3.99E-05 4.399127324 -0.52299251 APS(ph)PPVEHPR ddPTM_HeLa_Curcumin_4h_R1 2 APSPPVEHPR 10 0 Q86WR7;Q86WR7-2 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 0 APS(1)PPVEHPR;APS(1)PPVEHPR ; 116.71 0.0024266 208040000 842.31 702.17 589.66 671.38 767.97 605.54 487.43 489.87 815.79 566.82 TRUE FALSE FALSE 775.6402747 762.862446 611.5133183 668.6020075 758.8124593 479.9441782 501.1059739 639.2291079 726.299878 586.5169528 1.322451586 1.300665637 1.042618317 1.139953422 1.293760488 0.818295491 0.854375942 1.089873199 1.238327169 1 9.196028999 -5.256978387 24.99755408 1.165737683 0.914200981 0.495660087 0.123025899 315.1674055 1766060.125 0.021301583 0.05235951 5.53E-06 5.256978387 -0.251536703 KIS(ph)ENSYSLDDLEIGPGQLSSSTFDSEKNESRR ddPTM_HeLa_Curcumin_4h_R1 1 KISENSYSLDDLEIGPGQLSSSTFDSEKNESRR 33 3 Q9UHB6;F8VQE1;Q9UHB6-2;F8VRN8;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 KIS(0.256)ENS(0.256)Y(0.23)S(0.256)LDDLEIGPGQLSSSTFDSEKNESRR 40.453 0.0098827 37186000 1356.3 885.39 1049.7 1487.8 934.5 1159 504.53 464.57 1613.9 1289 TRUE FALSE FALSE 1248.947424 961.9191664 1088.602805 1481.643878 923.3566978 918.6103354 518.6857539 606.2152544 1436.859208 1333.792654 0.936387991 0.721190931 0.816170941 1.110850231 0.69227904 0.688720494 0.38888035 0.454504868 1.077273295 1 10.38131869 -5.160226239 1.351904361 0.944709054 0.40068482 0.719021436 0.124275179 0.178389469 0.580492706 0.018055 0.083149463 6.91E-06 5.160226239 -0.544024234 down APS(ph)PTAEQPPGGGDSAR ddPTM_HeLa_Curcumin_4h_R1 2 APSPTAEQPPGGGDSAR 17 0 Q15742-2;Q15742-3;Q15742 Q15742-2 NAB2 NGFI-A-binding protein 2 1 0 APS(0.576)PT(0.424)AEQPPGGGDSAR;APS(0.988)PT(0.012)AEQPPGGGDSAR ; 160.45 0.00014486 118813000 2950.3 3125.5 2559.1 2666.1 3099.7 3383.6 2969.7 2392.67 3430.6 3066 TRUE FALSE FALSE 2716.780642 3395.654293 2653.942497 2655.068385 3062.738102 2681.803219 3053.021789 3122.184069 3054.271763 3172.543272 0.856341556 1.070325604 0.836534688 0.836889573 0.965388913 0.845316514 0.962326288 0.984126551 0.962720285 1 11.63142413 -9.60555492 1.388681322 1.000266966 0.910729624 0.08273031 0.074710771 0.621253104 2.139629271 0.051940792 0.011820938 2.48E-10 9.60555492 -0.089537342 APS(ph)PTAEQPPGGGDSARR ddPTM_HeLa_Curcumin_4h_R1 3 APSPTAEQPPGGGDSARR 18 1 Q15742-2;Q15742-3;Q15742 Q15742-2 NAB2 NGFI-A-binding protein 2 1 0 APS(0.921)PT(0.078)AEQPPGGGDS(0.001)ARR;APS(0.928)PT(0.071)AEQPPGGGDS(0.001)ARR;APS(0.5)PT(0.5)AEQPPGGGDSARR ;; 77.644 0.008764 22305800 4371.12 3623.6 3941.74 3761.59 3813.76 4058.53 3286.79 2539.57 4875.72 4149.81 TRUE FALSE FALSE 4025.14124 3936.807838 4087.824352 3746.025537 3768.283403 3216.745129 3379.008481 3313.873202 4340.865714 4294.015589 0.937383937 0.916812656 0.951981721 0.872382845 0.877566307 0.749122834 0.786911089 0.771742238 1.010910563 1 12.06811171 -5.296232933 0.364351881 0.988911534 0.672044531 0.890986316 0.029231967 0.703191912 0.110284185 0.010830504 0.088452334 5.06E-06 5.296232933 -0.316867003 APS(ph)PIDHPR ddPTM_HeLa_Curcumin_4h_R1 1 APSPIDHPR 9 0 Q8NAS9-2;Q8NAS9 Q8NAS9-2 C5orf17 Uncharacterized protein C5orf17 1 0 APS(1)PIDHPR 78.548 0.016232 22108000 4016.6 3128.4 2877.1 3466.6 3654.2 2218 1482.5 846.68 3306.7 2749.4 TRUE FALSE FALSE 3698.681872 3398.804956 2983.727857 3452.256128 3610.626052 1757.961798 1524.09496 1104.828834 2943.963283 2844.941445 1.300090685 1.194683624 1.048783574 1.213471769 1.269138969 0.617925476 0.53572103 0.388348532 1.034806283 1 11.47418324 -5.152531009 4.10114739 1.154363946 0.485386704 0.891150162 0.102724766 0.064807391 1.877434037 0.018329517 0.049708571 7.04E-06 5.152531009 -0.668977242 down LEASYSDS(ph)PPGEEDLLVHVAEGSK ddPTM_HeLa_Curcumin_4h_R1 2 LEASYSDSPPGEEDLLVHVAEGSK 24 0 Q7Z3C6;C9JS65;C9JFV2;F2Z3I6;C9JX27;C9IYZ9;C9JKV7;C9JDK4;C9JXG2;Q7Z3C6-3 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 0 LEAS(0.108)Y(0.092)S(0.098)DS(0.703)PPGEEDLLVHVAEGSK;LEAS(0.057)Y(0.045)S(0.159)DS(0.739)PPGEEDLLVHVAEGSK ; 57.238 0.0038041 30580000 2897.2 2644.7 2350.19 2942.5 2741.11 2034.62 1053.93 920.7 3337.7 2750.3 TRUE FALSE FALSE 2667.883563 2873.296083 2437.290109 2930.324715 2708.424054 1612.616877 1083.500439 1201.417192 2971.562661 2845.87272 0.937457091 1.009636188 0.856429766 1.029675253 0.951702455 0.566651089 0.380726949 0.422161252 1.044165693 1 11.47465542 -5.151913287 2.862114621 0.969107046 0.406756101 0.953949521 0.053021016 0.034073665 0.534865813 0.006819298 0.020214985 7.05E-06 5.151913287 -0.562350946 down APS(ph)RQDVYGPQPQVR ddPTM_HeLa_Curcumin_4h_R1 1 APSRQDVYGPQPQVR 15 1 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12 O60716 CTNND1 Catenin delta-1 1 0 APS(1)RQDVYGPQPQVR 78.166 0.0076355 64976000 715.04 884.21 914.6 785.84 1009.9 1449.9 1057.5 943.78 1255.3 758.39 TRUE FALSE FALSE 658.4438295 960.6371724 948.4958806 782.5884023 997.8576021 1149.174396 1087.170604 1231.534177 1117.596731 784.7439961 0.839055581 1.224140837 1.208669178 0.997253125 1.271570865 1.464393996 1.385382506 1.569345141 1.424154548 1 9.616078276 -5.51995879 0.550590426 0.929382065 1.612552595 0.247179986 0.192719648 0.515086739 0.224999079 0.02854227 0.177657318 3.02E-06 5.51995879 0.68317053 APS(ph)VANVGSHCDLSLK ddPTM_HeLa_Curcumin_4h_R1 2 APSVANVGSHCDLSLK 16 0 P21333-2;P21333;Q60FE5 P21333-2;Q60FE5 FLNA Filamin-A 1 0 APS(0.999)VANVGS(0.001)HCDLSLK;APS(0.996)VANVGS(0.004)HCDLSLK ; 137.52 0.00041306 117780000 3720.5 3747.9 4586.3 4534.7 6454.3 6409 6004 4818.7 3432.4 3373.5 TRUE FALSE FALSE 3426.018499 4071.851776 4756.272313 4515.936613 6377.336688 5079.701156 6172.456081 6287.899447 3055.874307 3490.728874 0.981462217 1.166476092 1.36254418 1.293694462 1.826935554 1.455197851 1.768242766 1.801314188 0.875425855 1 11.76931259 -6.271842806 0.804288789 0.981695302 1.746718515 0.856172204 0.127913285 0.142710281 0.181808039 0.022326877 0.052109681 5.35E-07 6.271842806 0.765023212 FKMPFLSISS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 FKMPFLSISSPK 12 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 FKMPFLSIS(0.005)S(0.995)PK;FKMPFLSIS(0.099)S(0.901)PK ; 145.52 0.00037084 226190000 20752.8 13787.6 17706.9 17534.1 14798 26218 22832 22504.8 17533.6 13109.2 TRUE FALSE FALSE 19110.19398 14979.33871 18363.13329 17461.54854 14621.54351 20780.09126 23472.60447 29366.40992 15610.20795 13564.74372 1.408813493 1.104284682 1.353739788 1.287274489 1.077907833 1.531919193 1.730412675 2.164907094 1.150792692 1 13.72757417 -4.506664648 1.204415436 1.20056956 2.371338949 0.851236201 0.130013783 0.353534851 0.569679047 0.02530295 0.459700509 3.11E-05 4.506664648 1.170769389 up SRLT(ph)PVSPESSSTEEK ddPTM_HeLa_Curcumin_4h_R1 4 SRLTPVSPESSSTEEK 16 1 Q13501;E7EMC7;Q13501-2 Q13501 SQSTM1 Sequestosome-1 1 0 S(0.026)RLT(0.973)PVS(0.001)PESSSTEEK;S(0.003)RLT(0.997)PVSPESSSTEEK;S(0.02)RLT(0.926)PVS(0.054)PESSSTEEK;S(0.096)RLT(0.904)PVSPESSSTEEK ;;; 186.17 4.61E-05 1720600000 27825.4 21870.6 23539.7 23750.5 20688.9 13213.3 4875.66 2904.45 27495.9 20160.3 TRUE FALSE FALSE 25622.99023 23760.99721 24412.10199 23652.22672 20442.19838 10472.71264 5012.457897 3790.003435 24479.66856 20860.86892 1.228280103 1.139022411 1.170234187 1.133808319 0.97993034 0.502026674 0.240280398 0.181680037 1.173473102 1 14.34851163 -5.150719618 1.885982805 1.120935086 0.190317264 0.977348688 0.058037636 0.053568322 0.360962392 0.013066028 0.047105033 7.07E-06 5.150719618 -0.930617822 down APSAGLEEVAQPESVDVITSQSDS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 APSAGLEEVAQPESVDVITSQSDSPTR 27 0 A0A087WU78;A0A087WWC4;Q6T4R5-4;Q6T4R5-3;Q6T4R5-2;Q6T4R5 A0A087WU78 NHS Nance-Horan syndrome protein 1 0 APSAGLEEVAQPESVDVITS(0.003)QS(0.098)DS(0.732)PT(0.167)R 143.31 1.65E-08 4828400 882.4 1087.1 891.21 859.89 1072.9 1247.7 1048.3 666.97 966.44 903.36 TRUE FALSE FALSE 812.5571089 1181.06408 924.2390266 856.332003 1060.106368 988.9129555 1077.712477 870.3260826 860.4239499 934.7516928 0.869275889 1.263505687 0.98875352 0.916106395 1.134104786 1.057941872 1.15293985 0.9310773 0.920483971 1 9.868439368 DSAAPSPIPGADNLS(ph)ADPVVSPPTSIPFK ddPTM_HeLa_Curcumin_4h_R1 1 DSAAPSPIPGADNLSADPVVSPPTSIPFK 29 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 0 DS(0.054)AAPS(0.426)PIPGADNLS(0.515)ADPVVS(0.004)PPT(0.001)S(0.001)IPFK 51.052 0.0059165 7461500 8436.4 6343.3 7781.1 7378.7 6669.2 5819 3061.3 2097.9 8246.8 7701 TRUE FALSE FALSE 7768.650038 6891.586587 8069.474411 7348.168894 6589.674146 4612.073806 3147.191839 2737.540052 7342.146672 7968.609177 0.974906645 0.864841835 1.012657822 0.922139451 0.826954115 0.578780274 0.3949487 0.343540509 0.921383708 1 12.96011223 -5.142305336 1.254908178 0.979705066 0.315598805 0.966918687 0.043393551 0.055129362 0.150248974 0.006114643 0.030875458 7.21E-06 5.142305336 -0.664106261 down APSDS(ph)SLGTPSDGRPELR ddPTM_HeLa_Curcumin_4h_R1 1 APSDSSLGTPSDGRPELR 18 1 M0R0F9;W4VSQ9;Q15642-4;Q15642-2;Q15642-3;Q15642;M0R2H7;Q15642-5 M0R0F9 TRIP10 Cdc42-interacting protein 4 1 0 APS(0.326)DS(0.589)S(0.084)LGTPSDGRPELR 274.02 1.43E-54 17049000 1994.7 1720.6 1568.7 1627.5 1601.6 2339.4 1533.1 735.88 1780.3 1543.6 TRUE FALSE FALSE 1836.81739 1869.320997 1626.837402 1620.765836 1582.501966 1854.18207 1576.11466 960.2464244 1585.005544 1597.239985 1.14999462 1.170344478 1.018530351 1.014729065 0.990772821 1.160866299 0.986773857 0.601191075 0.992340261 1 10.64136538 -4.28284462 3.387757344 1.070918031 0.551002491 0.795739854 0.069516758 0.099131451 1.916093594 0.010592379 0.128818172 5.21E-05 4.28284462 -0.51991554 APSDSSLGT(ph)PSDGRPELR ddPTM_HeLa_Curcumin_4h_R1 1 APSDSSLGTPSDGRPELR 18 1 M0R0F9;W4VSQ9;Q15642-4;Q15642-2;Q15642-3;Q15642;M0R2H7;Q15642-5 M0R0F9 TRIP10 Cdc42-interacting protein 4 1 0 APS(0.002)DS(0.006)S(0.006)LGT(0.626)PS(0.36)DGRPELR 91.276 0.0020961 60199000 1160.9 1033 972.74 1155.9 1307.1 1671.3 1588.7 824.01 1146.8 923.03 TRUE FALSE FALSE 1069.01354 1122.287917 1008.7906 1151.117192 1291.513686 1324.653541 1633.274646 1075.246856 1020.998909 955.1052238 1.119262583 1.175041125 1.056208861 1.205225522 1.352221362 1.386918957 1.710046815 1.125788896 1.068991022 1 9.899515873 -5.850144052 1.558684713 1.06589692 1.438104284 0.522011046 0.139098062 0.193289983 0.946536205 0.020612116 0.047126437 1.41E-06 5.850144052 0.372207364 APSGNEEPCLLK ddPTM_HeLa_Curcumin_4h_R1 1 APSGNEEPCLLK 12 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 0 0 119.45 0.001131 1820100 371.62 376.17 412.62 360.08 320.4 557.97 337.72 216.32 431.86 349.11 FALSE FALSE TRUE 342.2058849 408.6844586 427.9120602 358.5900844 316.5794393 442.2407324 347.1955143 282.2749722 384.4860385 361.2415465 0.947304894 1.131332934 1.184559374 0.992660141 0.876364976 1.224224447 0.96111734 0.781402291 1.06434612 1 8.496820017 -4.305775152 4.355103173 1.010539272 0.772812685 0.316032155 0.107980741 0.183424772 7.156998327 0.015023434 0.118091407 4.95E-05 4.305775152 -0.237726587 APSK(ac)RPPISDSEELSAK ddPTM_HeLa_Curcumin_4h_R1 2 APSKRPPISDSEELSAK 17 2 P42568-2;P42568 P42568-2 MLLT3 Protein AF-9 0 1 ; APSK(1)RPPISDSEELSAK;APSK(1)RPPISDSEELSAK 118.5 5.87E-05 14570000 5263.5 4967.4 6020 5822.9 4677.2 5452.9 3054.1 2490.5 5321 4376.8 FALSE TRUE FALSE 4846.888421 5396.759922 6243.106496 5798.806383 4621.427445 4321.907073 3139.789826 3249.841985 4737.299612 4528.893474 1.070214711 1.191628806 1.378505927 1.280402468 1.020431916 0.954296474 0.693279682 0.717579692 1.04601701 1 12.14494289 -4.931983512 2.284837915 1.091036321 0.693208732 0.660757924 0.120720878 0.184452237 1.879057223 0.020979822 0.085548475 1.17E-05 4.931983512 -0.397827589 APSLT(ph)NDEVEEFR ddPTM_HeLa_Curcumin_4h_R1 2 APSLTNDEVEEFR 13 0 A0A3B3ISR7;E9PIF2;Q13206 A0A3B3ISR7 DDX10 Probable ATP-dependent RNA helicase DDX10 1 0 APS(0.304)LT(0.696)NDEVEEFR;APS(0.378)LT(0.622)NDEVEEFR ; 179.55 0.00046634 67295000 1042.13 749.49 1087.57 1111.38 892.82 1453.58 1314.81 667.3 1202.72 1115.96 TRUE FALSE FALSE 959.6443108 814.2725759 1127.876301 1106.781404 882.1737046 1152.091123 1351.70003 870.7566981 1070.784625 1154.739527 0.831048291 0.705156927 0.976736549 0.95846845 0.763959044 0.997706492 1.17056704 0.75407196 0.927295377 1 10.17335175 APSPAPS(ph)SVPLGSEKPSNVSQDR ddPTM_HeLa_Curcumin_4h_R1 2 APSPAPSSVPLGSEKPSNVSQDR 23 1 H0YM23;O75179-6;O75179-7;O75179-2;O75179;O75179-4 H0YM23 ANKRD17 Ankyrin repeat domain-containing protein 17 1 0 APS(0.025)PAPS(0.488)S(0.488)VPLGSEKPSNVSQDR;APS(0.021)PAPS(0.689)S(0.254)VPLGS(0.035)EKPSNVSQDR ; 135.49 5.62E-06 196289000 3159.6 2288 2542.8 2724.6 2915 2089.79 1134.78 1008.32 2741.5 2169.1 TRUE FALSE FALSE 2909.514326 2485.764525 2637.038405 2713.326327 2880.240529 1656.343997 1166.618873 1315.752126 2440.764309 2244.476064 1.296300002 1.107503246 1.174901549 1.208890739 1.283257405 0.737964652 0.519773363 0.586217936 1.087453927 1 11.132163 -5.100191524 3.96317312 1.156120105 0.564260708 0.89556358 0.087431533 0.06819405 1.894191982 0.017061654 0.04754303 7.94E-06 5.100191524 -0.591859397 LT(ph)PVSPESSSTEEK ddPTM_HeLa_Curcumin_4h_R1 2 LTPVSPESSSTEEK 14 0 Q13501;E7EMC7;Q13501-2 Q13501 SQSTM1 Sequestosome-1 1 0 LT(0.996)PVS(0.004)PESSSTEEK;LT(0.998)PVS(0.002)PESSSTEEK ; 209.79 5.08E-09 43463000 6563.5 6215.3 6343.4 5976 6057.6 4059.6 1951.78 1531.66 5762.2 5512 TRUE FALSE FALSE 6043.992049 6752.522837 6578.491984 5951.272895 5985.367076 3217.593199 2006.541694 1998.656083 5130.101076 5703.54159 1.059691063 1.183917524 1.153404754 1.043434645 1.049412366 0.564139517 0.35180627 0.350423689 0.899458871 1 12.47764232 -5.134020424 2.688710474 1.054864642 0.354624664 0.938752367 0.075338836 0.042439006 0.589133081 0.010141846 0.031150583 7.34E-06 5.134020424 -0.700239977 down APSS(ph)SSLNSATSSQSK ddPTM_HeLa_Curcumin_4h_R1 1 APSSSSLNSATSSQSK 16 0 Q5F1R6;Q5F1R6-3;Q5F1R6-2;A0A2R8Y534;A0A2R8Y4Q0 Q5F1R6 DNAJC21 DnaJ homolog subfamily C member 21 1 0 APS(0.275)S(0.598)S(0.085)S(0.041)LNSATSSQSK 137.27 3.36E-05 0 705.54 601.14 832.95 663.61 708.68 1136.4 1164.8 532.49 830.22 574.57 TRUE FALSE FALSE 649.6957645 653.099863 863.8198597 660.8641577 700.2294539 900.6978301 1197.481153 694.8437497 739.1469431 594.5362647 1.092777351 1.098502987 1.452930479 1.111562401 1.177774167 1.514958605 2.014143164 1.168715503 1.243232729 1 9.215621002 -5.68787616 0.536062855 1.029806508 1.668365058 0.282868557 0.242862079 0.873099963 0.38732431 0.052178918 0.270086089 2.05E-06 5.68787616 0.63855855 APSSSSLNSATSS(ph)QSKK ddPTM_HeLa_Curcumin_4h_R1 1 APSSSSLNSATSSQSKK 17 1 Q5F1R6;Q5F1R6-3;Q5F1R6-2;A0A2R8Y534;A0A2R8Y4Q0 Q5F1R6 DNAJC21 DnaJ homolog subfamily C member 21 1 0 APS(0.001)S(0.001)S(0.005)S(0.012)LNS(0.121)AT(0.041)S(0.121)S(0.528)QS(0.171)KK 63.447 0.013465 12808000 1236 1102.5 1156.8 1133.4 894.09 1437.9 1483.7 613.99 1073.5 1011.5 TRUE FALSE FALSE 1138.169296 1197.795187 1199.672026 1128.710291 883.4285607 1139.663332 1525.328629 801.1927245 955.7397358 1046.64955 1.087440678 1.144409022 1.146202209 1.078403264 0.84405383 1.088868124 1.457344179 0.765483274 0.913142069 1 10.03156275 -9.040263787 0.937404675 1.00236001 1.085557727 0.052336989 0.177468855 1.789888617 2.961220427 0.093589209 0.031758973 9.11E-10 9.040263787 0.083197717 APSVPAAEPEYPK ddPTM_HeLa_Curcumin_4h_R1 2 APSVPAAEPEYPK 13 0 F8VPP1;G3V213;F8VZG5;A0A5F9ZHP2;F8VY04;A0A5K1VW67;F8W1A4;P54819-3;P54819-5;P54819-2;P54819 F8VPP1 AK2 "Adenylate kinase 2, mitochondrial;Adenylate kinase 2, mitochondrial;Adenylate kinase 2, mitochondrial, N-terminally processed" 0 0 ; ; 134.3 0.0010358 4550800 1649.01 1402.19 1541.2 1822.84 1688.04 2278.77 1012.59 892.83 1850.96 1666.31 FALSE FALSE TRUE 1518.489118 1523.389056 1598.318228 1815.297571 1667.911225 1806.127415 1041.00055 1165.049757 1647.914319 1724.214148 0.880684757 0.883526595 0.926983594 1.05282605 0.967345748 1.047507594 0.603753629 0.675698989 0.955748055 1 10.75172325 -4.754747088 24.99984004 0.95209958 0.639726179 0.827843245 0.059000008 52.15280191 194817.4377 0.009468716 0.033858972 1.76E-05 4.754747088 -0.312373402 APSYSGLS(ph)MVSGVK ddPTM_HeLa_Curcumin_4h_R1 1 APSYSGLSMVSGVK 14 0 A0A2R8Y7K2;A0A2R8Y5N9;A0A2R8Y481;A0A2R8YFW8;A0A2R8YGN6;A0A2R8YCL5;A0A2R8Y4I8;A0A2U3TZR0;Q9UBP0-4;Q9UBP0-3;Q9UBP0-2;Q9UBP0 A0A2R8Y7K2 SPAST Spastin 1 0 APS(0.049)Y(0.012)S(0.007)GLS(0.932)MVSGVK 89.029 0.012665 17018000 2336.4 1295.7 1786.8 2294.3 1627.4 1734.9 1690.9 959.78 1414.3 1595.7 TRUE FALSE FALSE 2151.471475 1407.694534 1853.02038 2284.806795 1607.994318 1375.062184 1738.342103 1252.412504 1259.154828 1651.150456 1.303013585 0.852553763 1.122260163 1.383766565 0.973862989 0.83279036 1.052806603 0.758509014 0.762592424 1 10.68925587 -5.53662572 24.7886871 1.137248603 0.899314775 0.107120542 0.194046611 193.9141343 349667.2504 0.024443101 0.048905847 2.91E-06 5.53662572 -0.237933829 APTLAELDSS(ph)ESEEETLHK ddPTM_HeLa_Curcumin_4h_R1 1 APTLAELDSSESEEETLHK 19 0 J3KNG6;Q08AE8-4;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8 J3KNG6 SPIRE1 Protein spire homolog 1 1 0 APTLAELDS(0.211)S(0.789)ESEEETLHK 112.58 0.00018825 6214500 1622.1 1316.3 1456.6 1497.3 1654.2 2093 1398.2 3225 2066.3 1506.7 TRUE FALSE FALSE 1493.709073 1430.075107 1510.582877 1491.104569 1634.474745 1658.888207 1437.429729 4208.287654 1839.63206 1559.057713 0.958084528 0.91726887 0.968907607 0.956413965 1.048373471 1.064032584 0.921986221 2.69925072 1.179964054 1 10.60645862 -4.260255542 24.99944798 0.980524422 2.699251271 0.977214572 0.077704843 5.8667845 123875.4539 0.00636106 0.0525915 5.49E-05 4.260255542 1.718726849 APVASPAALGSTAT(ph)ASPAAPAR ddPTM_HeLa_Curcumin_4h_R1 1 APVASPAALGSTATASPAAPAR 22 0 A0A0C4DFM2;Q6ZN55;Q6ZN55-2 A0A0C4DFM2 ZNF574 Zinc finger protein 574 1 0 APVASPAALGS(0.027)T(0.027)AT(0.473)AS(0.473)PAAPAR 69.456 0.0073943 4720000 821.24 791.47 514.73 702.61 769.85 931.86 1215.8 288.07 964.76 798.2 TRUE FALSE FALSE 756.2379874 859.8811401 533.8063466 699.702786 760.6700416 738.5817318 1249.912076 375.9012169 858.9282417 825.9373906 0.915611759 1.041097243 0.646303646 0.847162017 0.920977849 0.894234527 1.513325453 0.455120716 1.039943525 1 9.689888613 -4.009282129 23.36301247 0.957879633 0.14998548 0.355963924 0.209878736 3841.8414 18617.38514 0.026060711 62942.60769 9.79E-05 4.009282129 -0.807894152 APVDEDRLS(ph)PLVAADSLLEHVR ddPTM_HeLa_Curcumin_4h_R1 1 APVDEDRLSPLVAADSLLEHVR 22 1 Q01094 Q01094 E2F1 Transcription factor E2F1 1 0 APVDEDRLS(1)PLVAADSLLEHVR 55.972 0.0062207 18330000 757.14 571.31 677.91 521.72 934.99 1165 615.46 254.73 925.38 710.92 TRUE FALSE FALSE 697.2115701 620.6914907 703.033941 519.5612609 923.8408549 923.3658677 632.7281512 332.3960044 823.8681292 735.6244171 0.947781985 0.843761404 0.955696854 0.706286046 1.255859422 1.255213729 0.860123912 0.451855589 1.119957563 1 9.522825557 -4.311557753 3.822962961 0.981671822 0.423106336 0.505421654 0.164022587 0.137574709 3.648055383 0.021695476 0.193100094 4.88E-05 4.311557753 -0.558565486 APVHFVEPLS(ph)PTGVAGHR ddPTM_HeLa_Curcumin_4h_R1 2 APVHFVEPLSPTGVAGHR 18 0 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 0 APVHFVEPLS(0.944)PT(0.056)GVAGHR;APVHFVEPLS(0.852)PT(0.148)GVAGHR ; 127.67 9.57E-05 75357000 4694.2 3655.3 4259.1 4330.2 4299.9 5916 4476.8 4056.5 4239.6 4083.4 TRUE FALSE FALSE 4322.649117 3971.247844 4416.945993 4312.28278 4248.626501 4688.954913 4602.406959 5293.308176 3774.526487 4225.297846 1.023040097 0.939874061 1.045357311 1.020586699 1.005521186 1.109733582 1.089250303 1.252765691 0.893316075 1 12.04483733 -1 0.614124816 1.006333598 17.99784012 0.738514703 0.047843591 42.40613681 0.288186894 0.005175586 973.4773 0.1 1 16.99150653 APVHFVEPLS(ph)PTGVAGHRK ddPTM_HeLa_Curcumin_4h_R1 1 APVHFVEPLSPTGVAGHRK 19 1 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 0 APVHFVEPLS(0.967)PT(0.033)GVAGHRK 63.606 0.015872 27489000 2792.5 1977.9 1929.4 2667.1 1989.8 3237.3 2573.7 2468.3 2652.9 2165.9 TRUE FALSE FALSE 2571.470678 2148.860863 2000.905261 2656.064247 1966.072935 2565.847488 2645.911095 3220.873307 2361.883507 2241.164864 1.14738131 0.958814274 0.892796997 1.185126668 0.877254934 1.144872262 1.180596367 1.437142514 1.053864241 1 11.13003306 -4.267102793 1.536178428 1.047190536 1.581399001 0.615902324 0.098925234 0.601641731 1.302205013 0.014765092 0.482627301 5.41E-05 4.267102793 0.534208465 APVPASELLASGVLSR ddPTM_HeLa_Curcumin_4h_R1 1 APVPASELLASGVLSR 16 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 179.67 3.62E-07 1492300 0 0 0 59.466 0 131.91 149.11 0 60.143 104.91 FALSE FALSE TRUE 0 0 0 59.21994545 0 104.5503791 153.2936253 0 53.54546337 108.5556147 0 0 0 0.545526324 0 0.963104298 1.412120651 0 0.493253744 1 6.762290536 -9.541079354 1.341589826 0.99564837 0.341426785 0.052286952 0.488134049 0.57616421 1.876851412 0.335170857 0.081984629 2.88E-10 9.541079354 -0.654221585 APVPEPGLDLSLS(ph)PRPDS(ph)PQPR ddPTM_HeLa_Curcumin_4h_R1 1 APVPEPGLDLSLSPRPDSPQPR 22 1 Q8TAP8 Q8TAP8 PPP1R35 Protein phosphatase 1 regulatory subunit 35 2 0 APVPEPGLDLS(0.153)LS(0.848)PRPDS(0.999)PQPR 64.246 0.0035884 0 1422.8 1185.8 1216.3 1078.8 1107.2 1202.5 1184.4 771.74 1056.3 952.56 TRUE FALSE FALSE 1310.183879 1288.295268 1261.377148 1074.336211 1093.997363 953.087945 1217.631076 1007.039973 940.4265327 985.6613891 1.329243382 1.307036354 1.27972665 1.089964793 1.109911959 0.966952704 1.235344196 1.021689583 0.954107103 1 9.944948303 -6.065611579 24.6124546 1.181813046 1.087741489 0.1015576 0.131582867 335.9491532 126021.7415 0.022534521 0.037369305 8.60E-07 6.065611579 -0.094071557 APVPEPGLDLSLS(ph)PRPDSPQPR ddPTM_HeLa_Curcumin_4h_R1 1 APVPEPGLDLSLSPRPDSPQPR 22 1 Q8TAP8 Q8TAP8 PPP1R35 Protein phosphatase 1 regulatory subunit 35 1 0 APVPEPGLDLS(0.298)LS(0.697)PRPDS(0.005)PQPR 70.569 0.0010276 4366400 674.67 576.82 645.84 718.03 753.97 576.41 403.53 620.73 745.77 490.48 TRUE FALSE FALSE 621.2691576 626.6777505 669.7753985 715.0589821 744.9794002 456.8560685 414.8519658 809.9877195 663.9608968 507.5241435 1.224117445 1.234774264 1.319691698 1.408916189 1.467869873 0.900166178 0.81740341 1.59595899 1.308235096 1 8.987332644 -8.955011688 0.804794817 1.001737144 1.234776222 0 0.244179747 1.059357593 1.274084939 0.143938711 0.046855181 1.11E-09 8.955011688 0.233039078 SETSS(ph)NPSSPEICPNK ddPTM_HeLa_Curcumin_4h_R1 1 SETSSNPSSPEICPNK 16 0 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 1 0 SET(0.016)S(0.09)S(0.891)NPS(0.001)S(0.002)PEICPNK 123.63 0.00071458 5490200 4619.6 3952 4315.4 4352.9 4491.6 3335 1879.8 1442.8 5344.5 4397.2 TRUE FALSE FALSE 4253.953785 4293.59327 4475.33252 4334.888853 4438.040604 2643.283407 1932.542129 1882.703078 4758.221721 4550.002373 0.93493441 0.94364638 0.983589052 0.952722328 0.975393031 0.580941105 0.424734312 0.413780681 1.04576247 1 12.15165158 -5.133811006 2.787988817 0.96816772 0.423200012 0.979009262 0.034238756 0.023614173 0.351520114 0.004494516 0.01362285 7.35E-06 5.133811006 -0.544967709 down APVPGT(ph)PDSLSSGSSR ddPTM_HeLa_Curcumin_4h_R1 2 APVPGTPDSLSSGSSR 16 0 A0A087WYB4;Q9UJZ1-2;Q9UJZ1 A0A087WYB4 STOML2 "Stomatin-like protein 2, mitochondrial" 1 0 APVPGT(0.91)PDS(0.081)LS(0.003)S(0.001)GS(0.003)S(0.001)R;APVPGT(1)PDSLSSGSSR ; 212.35 4.90E-11 94768000 4105.8 3684.9 3598.5 4213.2 3784.4 5943.2 4207.9 3247.8 4837.8 3127.5 TRUE FALSE FALSE 3780.821598 4003.406336 3731.863576 4195.766895 3739.273502 4710.513326 4325.962349 4238.039269 4307.105444 3236.180392 1.168297542 1.23707762 1.153169207 1.296518236 1.15545892 1.455578106 1.336749447 1.309580665 1.330922545 1 11.66007631 -7.249919143 0.103625019 0.6991481 1.666588067 0 0.124811713 3.128062431 0.2830448 1.215505039 1.285913009 5.62E-08 7.249919143 0.967439967 APVPGTPDS(ph)LSSGSSR ddPTM_HeLa_Curcumin_4h_R1 1 APVPGTPDSLSSGSSR 16 0 A0A087WYB4;Q9UJZ1-2;Q9UJZ1 A0A087WYB4 STOML2 "Stomatin-like protein 2, mitochondrial" 1 0 APVPGT(0.367)PDS(0.621)LS(0.008)S(0.002)GS(0.001)S(0.001)R 160.93 0.00025852 32953000 1737.2 1106 1123.9 1410 1461.1 2351 1767.4 1409.9 1716.7 1060.8 TRUE FALSE FALSE 1599.698787 1201.597712 1165.552723 1404.165794 1443.677337 1863.376099 1816.988487 1839.77202 1528.382305 1097.662721 1.457368239 1.094687547 1.061849601 1.27923247 1.315228539 1.697585299 1.655324949 1.676081354 1.392397023 1 10.10021911 -1 0.224455189 1.115811981 4.654710679 0.534343944 0.168391655 30.50843049 0.36779852 0.138296083 39.74938909 0.1 1 3.538898698 APVPSTCSSTFPEELS(ph)PPSHQAK ddPTM_HeLa_Curcumin_4h_R1 2 APVPSTCSSTFPEELSPPSHQAK 23 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;Q14980-4;Q14980-3;F5H6Y5;F5H4J1;F5H0Z7;F5H763 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 APVPSTCSSTFPEELS(0.998)PPS(0.002)HQAK;APVPSTCSSTFPEELS(0.999)PPS(0.001)HQAK ; 143.37 5.48E-06 31802000 5587.5 4364.9 4438.5 5234.3 4894.9 5706.5 3851.5 2084.77 5660.7 4894.9 TRUE FALSE FALSE 5145.243479 4742.182506 4602.994715 5212.641854 4836.531514 4522.907574 3959.562724 2720.406776 5039.735372 5064.997411 1.01584326 0.936265534 0.908785206 1.029149954 0.954893186 0.892973324 0.781750197 0.537099342 0.995012428 1 12.30634582 -3.912076705 0.855120361 0.997217635 1.71E-18 0.933597046 0.03635074 0.648463542 0.233233669 0.006089251 0.698608656 0.00012244 3.912076705 -0.997217635 APVQPQQS(ph)PAAAPGGTDEKPSGK ddPTM_HeLa_Curcumin_4h_R1 3 APVQPQQSPAAAPGGTDEKPSGK 23 1 Q13200;C9JPC0;F8WBS8 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 0 APVQPQQS(0.993)PAAAPGGT(0.007)DEKPS(0.001)GK;APVQPQQS(0.993)PAAAPGGT(0.007)DEKPSGK;APVQPQQS(1)PAAAPGGTDEKPSGK ;; 99.881 2.87E-05 163144200 9616.2 8557.4 9496.2 8899.7 9934 10234.3 9233.4 7836.3 8543.4 8247.5 TRUE FALSE FALSE 8855.067623 9297.063525 9848.137526 8862.8754 9815.543538 8111.590816 9492.464354 10225.5518 7606.210395 8534.100011 1.037610013 1.089401754 1.153974937 1.038524905 1.150155673 0.950491652 1.112298232 1.198199199 0.891272704 1 13.0590233 -1.000000394 0.036053812 0.689972516 1.672070506 0.374340641 0.072767862 789.8998706 2.19763363 17.57589834 50.27047467 0.099999909 1.000000394 0.982097991 APVSSTESVIQSNT(ph)PT(ph)PPPSQPLNETAEEESR ddPTM_HeLa_Curcumin_4h_R1 2 APVSSTESVIQSNTPTPPPSQPLNETAEEESR 32 0 B5MBZ0;Q9HC35;Q9HC35-2 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 2 0 APVSSTESVIQS(0.357)NT(0.936)PT(0.705)PPPS(0.001)QPLNETAEEESR;APVSSTESVIQS(0.008)NT(0.993)PT(0.998)PPPS(0.001)QPLNETAEEESR ; 143.38 1.27E-12 13766500 1128.48 926.36 1068.77 972.98 1405.9 1137.69 866.94 983.98 1376.12 1017.87 TRUE FALSE FALSE 1039.159617 1006.430431 1108.379556 968.9540666 1389.135561 901.7202696 891.2640032 1283.990972 1225.163079 1053.240907 0.986630514 0.955555775 1.052351413 0.919973826 1.318915314 0.85613867 0.846210964 1.219085742 1.163231575 1 10.04061974 SQSLPNSLDYTQTS(ph)DPGR ddPTM_HeLa_Curcumin_4h_R1 1 SQSLPNSLDYTQTSDPGR 18 0 H0YNE5;H0YLG5;Q96TC7 H0YNE5 RMDN3 Regulator of microtubule dynamics protein 3 1 0 SQSLPNS(0.011)LDY(0.005)T(0.005)QT(0.008)S(0.971)DPGR 182.25 5.50E-07 69705000 4892.8 3029.8 4372.2 4118.9 4251.3 2716.1 1404.9 910.18 4757.2 3766.1 TRUE FALSE FALSE 4505.529717 3291.682411 4534.237578 4101.857083 4200.606024 2152.750243 1444.317713 1187.689692 4235.347062 3896.971695 1.156161776 0.844677013 1.163528487 1.052575539 1.077915457 0.552416187 0.370625662 0.304772471 1.086830337 1 11.92813774 -5.126734997 2.700013271 1.065036425 0.341746406 0.920215229 0.088337213 0.054393324 0.761180284 0.013449265 0.041477653 7.47E-06 5.126734997 -0.723290019 down APVVTGK(ac)FGERPPPK ddPTM_HeLa_Curcumin_4h_R1 1 APVVTGKFGERPPPK 15 2 D6RIV8;Q06330-7 D6RIV8 RBPJ Recombining binding protein suppressor of hairless 0 1 APVVTGK(1)FGERPPPK 66.387 0.013372 3343100 813.55 928.5 819.9 739.15 813 951.43 934.33 734.22 1075.4 735.66 FALSE TRUE FALSE 749.156659 1008.755403 850.2862153 736.0915931 803.305506 754.0926932 960.5447852 958.0802981 957.4313105 761.2241302 0.984147282 1.325175284 1.116998505 0.966984051 1.05528119 0.99063162 1.261842271 1.258604739 1.257752182 1 9.572177484 -1 0.400114182 1.012078879 5.374556498 0 0.136989923 56.73650021 0.669958758 0.028779364 197.2891687 0.1 1 4.362477619 ANSPS(ph)LFGTEGKPK ddPTM_HeLa_Curcumin_4h_R1 1 ANSPSLFGTEGKPK 14 1 Q5JPT2;Q96B97-2;Q96B97;Q96B97-3 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 0 ANS(0.107)PS(0.889)LFGT(0.004)EGKPK 82.663 0.0072874 257630000 5467.9 3757.4 4077.8 4368.9 3912.7 3075.1 2021.2 1186.8 5007.4 4444.6 TRUE FALSE FALSE 5035.109945 4082.172913 4228.926855 4350.822649 3866.043608 2437.289596 2077.909432 1548.649857 4458.100748 4599.049519 1.094815336 0.887612298 0.919521922 0.946026485 0.840617956 0.529955067 0.451812798 0.33673259 0.96935263 1 12.16712002 -5.123085893 0.795614916 1.034367852 0.243139803 0.936284719 0.062304582 0.171902461 0.150808009 0.011415693 0.092796045 7.53E-06 5.123085893 -0.791228049 down AQAAAPAS(ph)VPAQAPK ddPTM_HeLa_Curcumin_4h_R1 1 AQAAAPASVPAQAPK 15 0 A0A3B3ITT5;P47914 A0A3B3ITT5 RPL29 60S ribosomal protein L29 1 0 AQAAAPAS(1)VPAQAPK 81.651 0.014482 11542000 3643.8 2807.4 3606.9 3731.4 3363.8 5680.6 5315.6 2786.6 3941 2888.4 TRUE FALSE FALSE 3355.389385 3050.059146 3740.574887 3715.960455 3323.688882 4502.379526 5464.74143 3636.221512 3508.68216 2988.771685 1.122665007 1.020505903 1.251542534 1.243306899 1.112058475 1.506431404 1.82842385 1.216627396 1.173954564 1 11.54533698 -5.252105944 4.373366657 1.087300272 1.555844744 0.530411575 0.161819066 0.095066114 4.679615253 0.021984888 0.055542473 5.60E-06 5.252105944 0.468544472 AQAAAPASVPAQAPK ddPTM_HeLa_Curcumin_4h_R1 2 AQAAAPASVPAQAPK 15 0 A0A3B3ITT5;P47914 A0A3B3ITT5 RPL29 60S ribosomal protein L29 0 0 ; ; 240.37 5.01E-48 17647100 11611.2 10044.7 9942.5 9963.6 10100.8 11284.2 10296.5 9851.3 11073.2 10060.2 FALSE FALSE TRUE 10692.16127 10912.91911 10310.9778 9922.373263 9980.354557 8943.729721 10585.39208 12854.91602 9858.497664 10409.7912 1.02712543 1.048332181 0.990507648 0.953176973 0.958746853 0.859165141 1.016868818 1.234887019 0.947040865 1 13.34565351 -4.270517446 5.139818365 0.995863781 1.244356531 0.669025949 0.053047588 0.074780259 6.432921762 0.007621317 0.064693364 5.36E-05 4.270517446 0.24849275 AQAEAQQPTFDALRDELR ddPTM_HeLa_Curcumin_4h_R1 1 AQAEAQQPTFDALRDELR 18 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 138.98 0.0002684 13239000 2039.4 1745.7 1887.7 1927 1812.5 2280.6 1729.6 1827.5 2134.7 2011.8 FALSE FALSE TRUE 1877.979338 1896.590529 1957.659823 1919.026585 1790.887121 1807.577852 1778.127921 2384.696337 1900.528751 2081.7099 0.902133068 0.911073406 0.940409527 0.921851111 0.860296202 0.868314001 0.85416701 1.145546907 0.912965227 1 11.02355332 -9.312000121 0.935615631 1.002169637 0.917947261 0 0.083371031 0.974557182 1.465822465 0.057518883 0.013838345 4.88E-10 9.312000121 -0.084222376 AQASPS(ph)EENKANK ddPTM_HeLa_Curcumin_4h_R1 1 AQASPSEENKANK 13 1 Q5T2D3 Q5T2D3 OTUD3 OTU domain-containing protein 3 1 0 AQAS(0.075)PS(0.925)EENKANK 75.968 0.011862 5545800 1268.7 1818.5 1469.8 1273.2 1651.3 1944.4 1613.5 961.86 1996.6 1686.5 TRUE FALSE FALSE 1168.281056 1975.683037 1524.272081 1267.931836 1631.609326 1541.109522 1658.770467 1255.126686 1777.577975 1745.105749 0.669461468 1.132127974 0.873455423 0.726564471 0.934963011 0.883103802 0.950527192 0.719226721 1.018607598 1 10.76909875 AQAVS(ph)EDAGGNEGR ddPTM_HeLa_Curcumin_4h_R1 2 AQAVSEDAGGNEGR 14 0 P55884-2;P55884;C9JZG1 P55884-2 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 0 AQAVS(1)EDAGGNEGR;AQAVS(1)EDAGGNEGR ; 176.19 0.00018706 15013000 2207.17 1856.2 1984.06 1817.05 2155.77 2275.69 1363.95 2107.55 2112.47 1589.81 TRUE FALSE FALSE 2032.470166 2016.641657 2057.591009 1809.531529 2130.063851 1803.686242 1402.218766 2750.132293 1880.737326 1645.055779 1.23550228 1.225880412 1.250772791 1.099981868 1.294827736 1.096428622 0.852383721 1.671756258 1.143266599 1 10.68392079 -9.279154529 0.927880862 0.995768072 1.201703705 0.056005503 0.198920988 0.937989241 1.401969477 0.133198899 0.033272505 5.26E-10 9.279154529 0.205935632 AQAVS(ph)EEEEEEEGK ddPTM_HeLa_Curcumin_4h_R1 2 AQAVSEEEEEEEGK 14 0 Q9GZR7-2;Q9GZR7;G3V529 Q9GZR7-2 DDX24 ATP-dependent RNA helicase DDX24 1 0 AQAVS(1)EEEEEEEGK;AQAVS(1)EEEEEEEGK ; 169.15 0.00020588 138887000 6574.9 6363.6 7343.3 6936.8 8370.3 7444.8 6515.4 4066.6 5950 5831.1 TRUE FALSE FALSE 6054.489727 6913.641228 7615.449158 6908.09736 8270.489639 5900.66456 6698.204589 5306.48762 5297.299886 6033.730291 1.003440564 1.145831997 1.2621461 1.144913184 1.370709203 0.977946357 1.110126616 0.879470471 0.877947742 1 12.55883449 -7.264766278 22.39468206 1.001624699 1.1361259 0.228916062 0.133398842 82.02591241 552148.8987 0.021132253 0.024723827 5.44E-08 7.264766278 0.134501201 AQAVSEDAGGNEGR ddPTM_HeLa_Curcumin_4h_R1 3 AQAVSEDAGGNEGR 14 0 P55884-2;P55884;C9JZG1 P55884-2 EIF3B Eukaryotic translation initiation factor 3 subunit B 0 0 ;; ;; 234.87 2.40E-37 9812000 3688.8 3451.83 3228.02 3324.81 3222.2 4255.1 3028.83 2831.19 3703.3 3295.57 FALSE FALSE TRUE 3396.827588 3750.190804 3347.653261 3311.052817 3183.777369 3372.544295 3113.810818 3694.406798 3297.057255 3410.090812 0.996110595 1.099733412 0.981690355 0.970957373 0.933634189 0.988989584 0.913116685 1.083374902 0.966853212 1 11.73559444 -6.541579101 24.99814444 1.007395581 0.972930287 0.094107013 0.052852304 426.9944203 570792.6335 0.007572566 0.010710044 2.87E-07 6.541579101 -0.034465295 AQAVSEEEEEEEGKS(ph)S(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 AQAVSEEEEEEEGKSSSPK 19 1 Q9GZR7-2;Q9GZR7;G3V529 Q9GZR7-2 DDX24 ATP-dependent RNA helicase DDX24 2 0 AQAVS(0.182)EEEEEEEGKS(0.785)S(0.778)S(0.254)PK 56.959 0.020133 158860000 5647.4 5259.7 5780.6 6495.9 5804.2 6397.6 5222.3 3153.8 5819.4 5416.9 TRUE FALSE FALSE 5200.402331 5714.325031 5994.834121 6469.021687 5734.988706 5070.665644 5368.823683 4115.379102 5181.026379 5605.136872 0.927792211 1.019480017 1.069525019 1.154123768 1.023166577 0.904646177 0.95783989 0.73421563 0.924335391 1 12.45253389 -3.721476951 1.298241525 0.992156683 0.142523293 0.565449275 0.070334039 3.154635477 1.711528953 0.011465805 5.022664749 0.000189899 3.721476951 -0.84963339 AQAVSEEEEEEEGKSS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 AQAVSEEEEEEEGKSSSPK 19 1 Q9GZR7-2;Q9GZR7;G3V529 Q9GZR7-2 DDX24 ATP-dependent RNA helicase DDX24 1 0 AQAVS(0.012)EEEEEEEGKS(0.097)S(0.446)S(0.446)PK 71.742 0.0040138 20076000 2740.7 2500.2 2243.5 3082.2 2799.8 3199.6 3248.2 1790.4 3248.4 2765.1 TRUE FALSE FALSE 2523.770703 2716.306147 2326.646084 3069.446673 2766.414214 2535.966893 3339.33575 2336.284718 2892.058647 2861.187019 0.882071212 0.949363369 0.813175115 1.072787851 0.966876403 0.886333845 1.167115511 0.816543869 1.010789797 1 11.48239809 -6.233374443 24.99649596 0.934414987 0.986072099 0.055725856 0.103512948 1791.795357 1595892.163 0.014584629 0.024183338 5.84E-07 6.233374443 0.051657112 AQAVSEEEEEEEGKSSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 AQAVSEEEEEEEGKSSSPK 19 1 Q9GZR7-2;Q9GZR7;G3V529 Q9GZR7-2 DDX24 ATP-dependent RNA helicase DDX24 1 0 AQAVS(0.003)EEEEEEEGKS(0.068)S(0.257)S(0.672)PK;AQAVSEEEEEEEGKS(0.127)S(0.127)S(0.745)PK ; 75.106 0.0030679 633850000 4794.2 4459.3 5310.3 6039.2 5065.1 6358.9 5823.6 4141 5908.4 4936.8 TRUE FALSE FALSE 4414.734011 4844.742022 5507.104389 6014.211391 5004.701991 5039.99246 5986.994543 5403.571837 5260.263302 5108.353433 0.864218592 0.948396012 1.078058608 1.177328756 0.979709422 0.986617807 1.172000846 1.057791304 1.029737541 1 12.31864263 -6.781332045 6.036307619 0.934649284 1.076182149 0.343166014 0.074456824 0.120093004 14.40226729 0.012582431 0.016956424 1.65E-07 6.781332045 0.141532865 AQT(ph)PPGPSLSGSK ddPTM_HeLa_Curcumin_4h_R1 2 AQTPPGPSLSGSK 13 0 Q9UQ35;Q9UQ35-2;I3L4D8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 AQT(0.957)PPGPS(0.036)LS(0.006)GSK;AQT(0.949)PPGPS(0.04)LS(0.008)GS(0.003)K ; 123.76 0.0062621 181520000 12937.9 10191.5 12114.8 11847.2 13426.3 18507.5 19335.1 17892.3 10605 10494.7 TRUE FALSE FALSE 11913.85156 11072.40785 12563.78515 11798.17943 13266.20014 14668.83588 19877.59087 23347.5799 9441.658032 10859.39004 1.097101358 1.019616001 1.156951274 1.08644955 1.221634004 1.350797404 1.830451875 2.149989991 0.869446442 1 13.40665545 -4.495176804 0.938252631 1.050682654 2.549987433 0.961570318 0.075137306 0.133133546 0.111892878 0.008153616 0.185537402 3.20E-05 4.495176804 1.499304779 up AQCPIVER ddPTM_HeLa_Curcumin_4h_R1 1 AQCPIVER 8 0 M0R0F0;M0R0R2;P46782 M0R0F0 RPS5 "40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed" 0 0 123.72 0.0023227 3792600 1217.9 1006.3 1129.4 991.83 1166.1 1233.2 823.68 1028.2 1212.3 1261.7 FALSE FALSE TRUE 1121.50193 1093.280088 1171.256558 987.7260703 1152.195019 977.420419 846.790244 1341.693447 1079.313723 1305.543981 0.859030371 0.837413449 0.897140636 0.756562846 0.882540179 0.748669086 0.648611044 1.027689198 0.826715713 1 10.35043534 -8.867635481 0.363558224 1.044910918 0.801893604 0 0.109696467 1.768175579 0.386157057 0.172887076 0.04068709 1.36E-09 8.867635481 -0.243017314 AQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSR ddPTM_HeLa_Curcumin_4h_R1 1 AQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSR 33 1 P43686-2;P43686 P43686-2 PSMC4 26S protease regulatory subunit 6B 0 0 49.968 0.0076793 0 729.21 557.39 649.91 668.63 636.5 647.33 562.73 505.71 483.44 597.99 FALSE FALSE TRUE 671.492259 605.5683079 673.9962363 665.8633862 628.9101532 513.0664611 578.5186893 659.898651 430.4078415 618.770108 1.085204748 0.978664451 1.089251448 1.076107875 1.016387419 0.829171375 0.934949316 1.066468212 0.695586028 1 9.273259693 -5.503650116 24.41219925 1.042523364 0.939356222 0 0.126373425 480.7432994 610338.98 0.009146857 0.020148515 3.14E-06 5.503650116 -0.103167141 AQEEAERLEADR ddPTM_HeLa_Curcumin_4h_R1 5 AQEEAERLEADR 12 1 E7EQR4;P15311 E7EQR4 EZR Ezrin 0 0 ;;;; ;;;; 128.57 0.0022907 154313700 13807 11288.7 10511.2 12429.2 10808.8 16318.9 11457.5 13826.9 15863.1 12234.3 FALSE FALSE TRUE 12714.16138 12264.44493 10900.75432 12377.77126 10679.91212 12934.17619 11778.96661 18042.65816 14122.95762 12659.44101 1.004322495 0.968798299 0.861077065 0.977750222 0.843632204 1.021701999 0.930449188 1.4252334 1.115606732 1 13.62792608 -4.257882007 24.85307504 0.976016525 1.425233585 0.769851603 0.074710918 96.44719454 673782.1421 0.008622693 0.084714769 5.52E-05 4.257882007 0.449217061 AQENYEGS(ph)EEVSPPQTK ddPTM_HeLa_Curcumin_4h_R1 1 AQENYEGSEEVSPPQTK 17 0 Q93008;Q93008-3 Q93008 USP9X Probable ubiquitin carboxyl-terminal hydrolase FAF-X 1 0 AQENY(0.001)EGS(0.799)EEVS(0.2)PPQTK 126.83 0.00035877 7629800 1145.4 1000.1 1062.8 1284.8 1124.6 1691 958.82 965.81 1275.1 1029.2 TRUE FALSE FALSE 1054.740381 1086.544188 1102.188303 1279.483838 1111.18988 1340.267539 985.7219087 1260.281023 1135.22472 1064.964623 0.990399454 1.020263175 1.034952973 1.201433184 1.043405438 1.258508977 0.925591223 1.183401772 1.065974113 1 10.05658979 -6.478763139 6.721718323 0.998485776 1.115358572 0.228086982 0.08878877 0.196046261 23.54606608 0.01180831 0.017909496 3.32E-07 6.478763139 0.116872796 AQENYEGSEEVS(ph)PPQTK ddPTM_HeLa_Curcumin_4h_R1 2 AQENYEGSEEVSPPQTK 17 0 Q93008;Q93008-3 Q93008 USP9X Probable ubiquitin carboxyl-terminal hydrolase FAF-X 1 0 AQENY(0.001)EGS(0.061)EEVS(0.936)PPQT(0.003)K;AQENYEGS(0.013)EEVS(0.986)PPQT(0.001)K ; 119.51 0.00066498 42640500 3276.4 2795.1 3262.2 3433.8 3239.1 3892.9 2701.3 2798.9 3098 2815.6 TRUE FALSE FALSE 3017.069483 3036.695989 3383.100002 3419.591845 3200.475848 3085.468658 2777.091208 3652.271725 2758.157151 2913.44189 1.035568786 1.042305323 1.161203871 1.173729209 1.098520571 1.059045889 0.95319945 1.253593469 0.946700588 1 11.50850882 -6.93810753 6.536069027 1.017877886 1.108234101 0.323037505 0.077776841 0.21921879 17.98157387 0.011767764 0.015486048 1.15E-07 6.93810753 0.090356215 AQGAGVTLPPT(ph)PSGSR ddPTM_HeLa_Curcumin_4h_R1 2 AQGAGVTLPPTPSGSR 16 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 0 AQGAGVTLPPT(0.957)PS(0.043)GSR;AQGAGVT(0.001)LPPT(0.829)PS(0.133)GS(0.037)R ; 191.15 1.11E-06 14192000 3731.1 3504.6 3192.6 3805.6 3742 5621.3 3948.5 2230.62 3840.3 3660.8 TRUE FALSE FALSE 3435.779498 3807.522008 3310.920564 3789.853436 3697.379094 4455.379015 4059.284283 2910.725769 3419.028698 3788.012528 0.907013763 1.005150321 0.874052169 1.000485983 0.976073618 1.176178532 1.071613215 0.768404473 0.902591708 1 11.88722539 -5.903242557 3.127271214 0.95355383 1.016564419 0.053430721 0.103997853 0.552655681 10.84908529 0.015231933 0.02911376 1.25E-06 5.903242557 0.063010589 AQGEPVAGHES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 AQGEPVAGHESPK 13 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0YAB3 D6REX3 SEC31A Protein transport protein Sec31A 1 0 AQGEPVAGHES(1)PK;AQGEPVAGHES(1)PK ; 154.81 0.0004 227778000 12199.6 11658.5 12896.6 11409.6 13424.3 11752.2 11084.3 10053.3 10833.1 10555.4 TRUE FALSE FALSE 11233.98879 12666.20879 13374.55934 11362.3901 13264.22399 9314.661245 11395.29563 13118.50489 9644.736033 10922.19936 1.028546395 1.159675663 1.224529868 1.04030239 1.214427932 0.852819193 1.04331511 1.201086379 0.883039735 1 13.41497578 -7.43589679 6.828955432 1.012443662 1.099371219 0.205011022 0.1127911 0.396636457 26.36494555 0.017882214 0.020323792 3.67E-08 7.43589679 0.086927556 AQGEPVAGHES(ph)PKIPYEK ddPTM_HeLa_Curcumin_4h_R1 4 AQGEPVAGHESPKIPYEK 18 1 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0YAB3 D6REX3 SEC31A Protein transport protein Sec31A 1 0 AQGEPVAGHES(0.915)PKIPY(0.085)EK;AQGEPVAGHES(0.99)PKIPY(0.01)EK;AQGEPVAGHES(0.991)PKIPY(0.009)EK;AQGEPVAGHES(0.616)PKIPY(0.384)EK ;;; 77.468 0.0029435 1198547000 27325.1 22137.9 23136.8 24316.7 22098.2 25225 19941.9 17895 27884 25477.4 TRUE FALSE FALSE 25162.2895 24051.40143 23994.27016 24216.08394 21834.6934 19993.05066 20501.41604 23351.10312 24825.19496 26362.73775 0.954464204 0.912325634 0.910158512 0.918572425 0.828240739 0.758382943 0.777666426 0.885761689 0.941677423 1 14.68621258 -6.362220077 0.603908766 0.986999866 0.794474981 0.683612913 0.041488664 0.282694843 0.202532496 0.009673995 0.02388373 4.34E-07 6.362220077 -0.192524885 AQHEDQVEQYK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 AQHEDQVEQYKK 12 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 1 AQHEDQVEQYK(1)K 131.69 8.53E-05 15811000 2914.5 4385.9 2873.9 3196.2 6244.9 7808.3 5883 4679.9 9019.3 3436.8 FALSE TRUE FALSE 2683.81425 4764.997653 2980.409262 3182.974971 6170.433646 6188.770562 6048.061147 6106.779966 8029.905355 3556.228544 0.754679913 1.339901976 0.838081475 0.895042299 1.735106045 1.740262327 1.700695293 1.717206836 2.257983494 1 11.79613233 -5.761049941 24.99993299 0.916277032 1.722912206 0.123890218 0.449477348 2.748539203 176419.6687 0.023579223 0.044932657 1.73E-06 5.761049941 0.806635174 AQHEDQVEQYKK ddPTM_HeLa_Curcumin_4h_R1 2 AQHEDQVEQYKK 12 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 94.767 0.0012892 30215000 30420 24463 25867 27166 26134 30787 23660 21331 30113 24913 FALSE FALSE TRUE 28012.2249 26577.47271 26825.65377 27053.59429 25822.36912 24401.42916 24323.83592 27834.7237 26809.67924 25778.7249 1.086641213 1.030984768 1.040612128 1.049454323 1.001693033 0.946572387 0.943562415 1.079755644 1.039992449 1 14.65389328 -5.631797544 4.623110063 1.041478285 0.983721369 0.255682267 0.040241832 0.227790845 8.265958126 0.006618694 0.013541721 2.33E-06 5.631797544 -0.057756916 AQHPDYS(ph)FGELSR ddPTM_HeLa_Curcumin_4h_R1 1 AQHPDYSFGELSR 13 0 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-7;Q86U86-3;Q86U86-2;Q86U86-4;Q86U86-9 Q86U86-8 PBRM1 Protein polybromo-1 1 0 AQHPDYS(1)FGELSR 120.39 0.0011675 6844100 2130.9 2088.4 1773.3 1811.5 1869 3749.6 3909.7 1123.3 2075.5 1670.8 TRUE FALSE FALSE 1962.237016 2268.91199 1839.020058 1804.004493 1846.713396 2971.890693 4019.39566 1465.788999 1847.822843 1728.860176 1.134988846 1.312374489 1.063718214 1.043464659 1.068168162 1.718988461 2.324881859 0.847835481 1.068809883 1 10.75560548 -5.261679426 24.74319153 1.082933324 1.699999958 0.328345092 0.343743757 12.78200367 1317640.216 0.043716859 0.10385971 5.47E-06 5.261679426 0.617066634 AQIHDLVLVGGS(ph)TR ddPTM_HeLa_Curcumin_4h_R1 1 AQIHDLVLVGGSTR 14 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 1 0 AQIHDLVLVGGS(0.754)T(0.246)R 77.795 0.0077343 0 1438.2 1327.7 1482.7 1570.5 1662.4 1860 1393.9 918.72 1916.7 1221.1 TRUE FALSE FALSE 1324.364952 1442.460472 1537.650166 1564.001687 1642.576966 1474.215033 1433.009083 1198.833499 1706.442805 1263.533134 1.048144221 1.141608742 1.216944871 1.237800296 1.299987251 1.166740304 1.134128614 0.948794667 1.350532692 1 10.30324778 -7.282119895 2.374377917 1.019468835 1.175606747 0 0.135852687 0.230108257 2.466717112 0.016215614 0.019068684 5.22E-08 7.282119895 0.156137913 AQIHDLVLVGGSTR ddPTM_HeLa_Curcumin_4h_R1 2 AQIHDLVLVGGSTR 14 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 0 ; ; 81.619 0.0084093 16382300 3589.9 3030.2 3088.1 2805.9 3489.9 4623.3 3660.8 3036.7 3250.4 3095.7 FALSE FALSE TRUE 3305.755627 3292.116986 3202.547703 2794.289929 3448.285222 3664.375465 3763.512195 3962.575851 2893.839252 3203.275345 1.031992343 1.027734625 0.999772844 0.872322741 1.076487298 1.143946452 1.174895003 1.237038788 0.903400095 1 11.6453321 -5.231481351 2.310932057 1.005955499 1.199783444 0.715897444 0.058122409 0.117548837 1.213651949 0.007181142 0.021629297 5.87E-06 5.231481351 0.193827945 LFPNAT(ph)SPELLEDFR ddPTM_HeLa_Curcumin_4h_R1 1 LFPNATSPELLEDFR 15 0 Q7Z591-6;Q7Z591-3;Q7Z591 Q7Z591-6 AKNA AT-hook-containing transcription factor 1 0 LFPNAT(0.75)S(0.25)PELLEDFR 116.58 0.0045817 1498200 328.13 341.26 456.32 448.01 374.01 273.31 105.87 128.32 405.99 373.37 TRUE FALSE FALSE 302.1581643 370.7569938 473.2316206 446.1562533 369.550175 216.6224252 108.8404273 167.4441773 361.4539127 386.3445797 0.782095 0.95965367 1.224895198 1.154814321 0.956529985 0.560697462 0.281718531 0.433406306 0.93557392 1 8.593744347 -5.116598693 3.239873831 0.948393046 0.364094215 0.810185703 0.128285848 0.10271156 2.014954441 0.022882591 0.066766217 7.65E-06 5.116598693 -0.584298831 down AQKLPDLS(ph)PVENK ddPTM_HeLa_Curcumin_4h_R1 2 AQKLPDLSPVENK 13 1 E7EPN9;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;Q9Y520-2;A0A2R8Y7F4;A0A2R8YET2;H7C5N8 E7EPN9 PRRC2C Protein PRRC2C 1 0 AQKLPDLS(1)PVENK;AQKLPDLS(1)PVENK ; 73.168 0.013621 69814000 6808.2 5530.3 6350.5 6618.1 5807.8 7597.8 5990.5 7856.4 7180.2 5895.5 TRUE FALSE FALSE 6269.323786 6008.314489 6585.855116 6590.716056 5738.545778 6021.930635 6158.577307 10251.78019 6392.550024 6100.368186 1.027695968 0.984910141 1.079583218 1.080380045 0.940688431 0.987142161 1.009541903 1.68051827 1.047895771 1 12.5746806 -4.261225952 24.96738548 1.013632812 1.680518472 0.958256629 0.041504929 2.183855026 255301.8617 0.005503668 0.042747053 5.48E-05 4.261225952 0.66688566 AQLDYVDLYLIHSPMS(ph)LKPGEELSPTDENGK ddPTM_HeLa_Curcumin_4h_R1 1 AQLDYVDLYLIHSPMSLKPGEELSPTDENGK 31 1 S4R3Z2;A0A0A0MSS8;P42330;S4R3D5 S4R3Z2 AKR1C3 Aldo-keto reductase family 1 member C3 1 0 AQLDYVDLYLIHS(0.004)PMS(0.548)LKPGEELS(0.398)PT(0.05)DENGK 76.804 8.68E-06 16420000 550.73 363.66 340.19 286.37 591.67 1541.5 800.69 1165.8 502.91 343.72 TRUE FALSE FALSE 507.1391394 395.09315 352.7977407 285.1850768 584.6147217 1221.775524 823.1552065 1521.247053 447.7420312 355.6642444 1.425892952 1.110859908 0.991940422 0.801837917 1.643726438 3.435193565 2.31441653 4.277199851 1.258889636 1 8.474372135 -5.36126818 3.702648382 1.157018027 3.249405222 0.814615904 0.477315487 0.071240721 1.787651466 0.063789356 0.152390975 4.35E-06 5.36126818 2.092387195 AQLEPVAS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 6 AQLEPVASPAK 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 AQLEPVAS(1)PAK;AQLEPVAS(1)PAK;AQLEPVAS(1)PAK;AQLEPVAS(1)PAK;AQLEPVAS(1)PAK;AQLEPVAS(1)PAK ;;;;; 154.47 0.0004525 2311872100 37299.2 31072.2 36645.6 32950 38164 41005.4 37967 26782.2 33699.2 26198 TRUE FALSE FALSE 34346.92896 33757.94251 38003.71817 32813.66163 37708.91923 32500.41781 39032.25184 34947.96949 30002.48207 27108.37855 1.267022625 1.245295526 1.401917791 1.210461982 1.391042963 1.198906742 1.439859332 1.289194388 1.106760481 1 14.7264512 -9.151858716 0.408355766 0.913046002 1.331623212 0.594169607 0.082522578 0.774517094 0.181271763 0.140018622 0.023851868 7.05E-10 9.151858716 0.41857721 AQLFALTGVQPAR ddPTM_HeLa_Curcumin_4h_R1 2 AQLFALTGVQPAR 13 0 A6NJA2;P54578-2;P54578-3;P54578;J3QQT6;J3KS55 A6NJA2 USP14 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 14 0 0 ; ; 147.26 0.0003237 1661350 401.693 374.55 706.59 378.95 441.6 385.81 547.79 213.806 438.87 377.24 FALSE FALSE TRUE 369.8985752 406.924433 732.776847 377.3820053 436.3342084 305.788657 563.1595131 278.9944652 390.727059 390.3490619 0.947609745 1.042462946 1.87723481 0.966780869 1.117805193 0.783372337 1.442707484 0.714730718 1.000968357 1 8.608620992 -6.989423349 24.99912335 0.976300948 1.164093979 0.055502711 0.312432403 443.4395259 1048115.181 0.047579696 0.062498843 1.02E-07 6.989423349 0.187793031 AQLGGPEAAK ddPTM_HeLa_Curcumin_4h_R1 2 AQLGGPEAAK 10 0 P04792;C9J3N8 P04792 HSPB1 Heat shock protein beta-1 0 0 ; ; 166.19 2.81E-12 50834000 15336.8 13076 14377.1 14341.3 14802.5 17736.8 14304.1 13361.2 14740.1 12462.5 FALSE FALSE TRUE 14122.8761 14206.23117 14909.92797 14281.9595 14625.98986 14057.98775 14705.43455 17434.96837 13123.14791 12895.57095 1.09517261 1.101636464 1.156205339 1.107508893 1.134187072 1.090140778 1.140347691 1.352012132 1.017647684 1 13.65458803 -1 0.137436341 0.97722846 1.865440097 0.640330003 0.054515732 38.38232154 0.350407209 0.158975953 6.700041365 0.1 1 0.888211637 AQLGGPEAAKS(ph)DETAAK ddPTM_HeLa_Curcumin_4h_R1 4 AQLGGPEAAKSDETAAK 17 1 P04792;C9J3N8 P04792 HSPB1 Heat shock protein beta-1 1 0 AQLGGPEAAKS(0.993)DET(0.007)AAK;AQLGGPEAAKS(0.674)DET(0.326)AAK;AQLGGPEAAKS(0.5)DET(0.5)AAK;AQLGGPEAAKS(0.5)DET(0.5)AAK ;;; 198.42 4.37E-07 155578200 11171.5 8942.02 10241.2 9279.6 9808.7 11681 10052.6 24934.6 10927.6 9649.63 TRUE FALSE FALSE 10287.26399 9714.928364 10620.74788 9241.203474 9691.737659 9258.228928 10334.6489 32537.04476 9728.86962 9984.953924 1.030276561 0.972956754 1.063675202 0.925512881 0.970634189 0.927217992 1.035022192 3.258607401 0.974352981 1 13.28554006 -4.261497972 6.985645323 1.000350837 3.292254636 0.996097053 0.042623257 0.004445643 1.631416783 0.005871294 0.047878663 5.48E-05 4.261497972 2.291903799 AQLLQPTLEINPR ddPTM_HeLa_Curcumin_4h_R1 2 AQLLQPTLEINPR 13 0 I3L0K7;Q12931-2;Q12931 I3L0K7 TRAP1 "Heat shock protein 75 kDa, mitochondrial" 0 0 ; ; 144.1 7.92E-06 957330 748.83 557.94 741.46 776.85 908.39 1166.56 1082.23 625.51 855.04 949.82 FALSE FALSE TRUE 689.5593153 606.1658475 768.9391599 773.6356005 897.5580425 924.6023062 1112.594461 816.2251195 761.2442512 982.8261743 0.701608619 0.616757941 0.782375541 0.787154047 0.9132419 0.940758733 1.132035847 0.830487772 0.774546172 1 9.940792469 -5.454761947 2.650913985 0.82503139 0.985329983 0.303343922 0.119579384 0.383629349 5.270492741 0.022393372 0.054891498 3.51E-06 5.454761947 0.160298592 AQLS(ph)PGIYDDTSAR ddPTM_HeLa_Curcumin_4h_R1 1 AQLSPGIYDDTSAR 14 0 A0A088AWL3;O75376-2;O75376;E7EVK1 A0A088AWL3 NCOR1 Nuclear receptor corepressor 1 1 0 AQLS(1)PGIYDDTSAR 224.55 5.42E-15 227390000 3346.8 3015.5 2835.3 2890.8 2819.9 3685.1 3278.9 1760.5 3412.5 2667.6 TRUE FALSE FALSE 3081.897248 3276.146383 2940.378712 2878.838636 2786.274534 2920.76872 3370.897109 2297.268346 3038.157288 2760.298901 1.116508523 1.186881023 1.065239243 1.042944528 1.009410442 1.058134943 1.221207279 0.832253472 1.100662427 1 11.43060878 -6.284565657 6.961024513 1.069131069 1.043347211 0.054315648 0.099729546 0.950483148 201.2643842 0.015394933 0.023963025 5.19E-07 6.284565657 -0.025783859 AQLSVQTS(ph)PVPTPDPK ddPTM_HeLa_Curcumin_4h_R1 1 AQLSVQTSPVPTPDPK 16 0 J3KQV8;O43426;A0A0D9SGJ6 J3KQV8 SYNJ1 Synaptojanin-1 1 0 AQLSVQT(0.057)S(0.943)PVPTPDPK 164.53 0.00022181 5416400 3552.2 2554.2 2777.1 3087.4 3047.8 2584.9 1763.2 2320.9 3075.5 2593.3 TRUE FALSE FALSE 3271.039622 2774.973667 2880.021769 3074.625157 3011.456976 2048.762602 1812.670647 3028.531726 2738.125345 2683.416982 1.218982977 1.03411944 1.073266581 1.145787322 1.122247118 0.763490213 0.675508376 1.128610181 1.020387574 1 11.38985554 -5.268729655 24.86937846 1.102329395 0.837833467 0.416280166 0.124500539 334.7645357 1141986.259 0.01823946 0.041591618 5.39E-06 5.268729655 -0.264495928 AQLYLPS(ph)TSPPHEGLDGFAQELSR ddPTM_HeLa_Curcumin_4h_R1 3 AQLYLPSTSPPHEGLDGFAQELSR 24 0 Q8N137;Q8N137-3;Q8N137-2;I3L465;I3L1Z8;I3L1A6;Q8N137-4;Q8N137-5 Q8N137 CNTROB Centrobin 1 0 AQLY(0.007)LPS(0.522)T(0.236)S(0.236)PPHEGLDGFAQELSR;AQLY(0.027)LPS(0.324)T(0.324)S(0.324)PPHEGLDGFAQELSR;AQLY(0.009)LPS(0.369)T(0.311)S(0.311)PPHEGLDGFAQELSR ;; 89.631 3.24E-05 31719800 5050.87 4824.79 4747.42 4935.62 6065.6 9061.5 6218.6 3194.08 6379.7 5082.1 TRUE FALSE FALSE 4651.08831 5241.823349 4923.363561 4915.197712 5993.271682 7182.042756 6393.077179 4167.940288 5679.862871 5258.702597 0.884455476 0.996790226 0.936231603 0.934678777 1.139686372 1.365744235 1.215713774 0.792579579 1.080088247 1 12.36049119 -5.748081571 8.406634129 0.946961561 1.15204377 0.20353914 0.143618922 0.142347191 62.20533762 0.019743605 0.038511047 1.79E-06 5.748081571 0.20508221 AQLYLPSTS(ph)PPHEGLDGFAQELSR ddPTM_HeLa_Curcumin_4h_R1 1 AQLYLPSTSPPHEGLDGFAQELSR 24 0 Q8N137;Q8N137-3;Q8N137-2;I3L465;I3L1Z8;I3L1A6;Q8N137-4;Q8N137-5 Q8N137 CNTROB Centrobin 1 0 AQLY(0.017)LPS(0.278)T(0.202)S(0.503)PPHEGLDGFAQELSR 71.143 0.00043885 6790100 2116.4 1949.1 1852.4 1408 1847.4 3597.6 2465.8 1204.7 2181.6 1748 TRUE FALSE FALSE 1948.884707 2117.571519 1921.051574 1402.174069 1825.370962 2851.417207 2534.983712 1572.007484 1942.283938 1808.74287 1.077480243 1.170742151 1.062092133 0.775220233 1.009193176 1.576463551 1.401516906 0.869116064 1.073830875 1 10.82077161 -5.349894381 24.99997389 1.027969621 1.294309477 0.277689966 0.190529334 62.27471168 17598.77854 0.026203214 0.058592171 4.47E-06 5.349894381 0.266339856 AQMVQEDLEK ddPTM_HeLa_Curcumin_4h_R1 1 AQMVQEDLEK 10 0 P26038 P26038 MSN Moesin 0 0 180.07 1.03E-15 6256900 2357.3 1452 1602.4 1701.8 1585.5 2644.4 1817.2 1769.3 2584.3 1677.2 FALSE FALSE TRUE 2170.717218 1577.50441 1661.786354 1694.758403 1566.593948 2095.921631 1868.185741 2308.751425 2300.808756 1735.482575 1.250785948 0.908971621 0.957535603 0.976534381 0.902684919 1.207688087 1.076464707 1.330322446 1.325745812 1 10.76112116 -3.580527786 1.434879361 1.072848294 2.360313909 0.237221037 0.14068107 8.946094976 3.961893507 0.020582011 26.7774219 0.000262707 3.580527786 1.287465615 AQNGIAIMVY(ph)TNSSNTLY(ph)WELNQAVR ddPTM_HeLa_Curcumin_4h_R1 1 AQNGIAIMVYTNSSNTLYWELNQAVR 26 0 H7C1W0;Q96L15-2;Q96L15 H7C1W0 ART5 NAD(P)(+)--arginine ADP-ribosyltransferase;Ecto-ADP-ribosyltransferase 5 2 0 AQNGIAIMVY(0.794)T(0.205)NS(0.015)S(0.015)NT(0.059)LY(0.912)WELNQAVR 49.106 0.014503 16773000 2511.9 1332.5 1538.9 1784.8 1607.9 1988.8 1631.5 1297.7 2414.2 1703.7 TRUE FALSE FALSE 2313.080464 1447.675362 1595.932988 1777.414971 1588.726843 1576.300462 1677.275499 1693.362756 2149.3683 1762.903448 1.312085734 0.821188117 0.905286668 1.008231604 0.90119901 0.894150195 0.951427885 0.960553318 1.219220657 1 10.78373775 -7.251375995 24.9954711 1.14737382 0.922554068 0.642813621 0.086870812 487.4967098 1210846.271 0.020328763 0.024739225 5.61E-08 7.251375995 -0.224819753 AQPFGFIDS(ph)DTDAEEER ddPTM_HeLa_Curcumin_4h_R1 2 AQPFGFIDSDTDAEEER 17 0 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 AQPFGFIDS(0.799)DT(0.201)DAEEER;AQPFGFIDS(0.603)DT(0.397)DAEEER ; 195.55 1.03E-07 11748700 2725.6 1948.75 2419.5 2360.9 2604.2 2733.1 2119.42 1292.43 1867.89 1844.94 TRUE FALSE FALSE 2509.865884 2117.191267 2509.168798 2351.131221 2573.146616 2166.224252 2178.885221 1686.485957 1662.98714 1909.051528 1.314718774 1.109027827 1.314353626 1.231570331 1.347866508 1.134712301 1.141344374 0.88341563 0.871106472 1 10.89864033 -4.196135292 2.410272507 1.179804426 0.782541784 0.254947862 0.142089112 0.724345293 4.343863056 0.019208862 0.63495871 6.37E-05 4.196135292 -0.397262642 AQPFGFIDS(ph)DTDAEEERIPATPVVIPMKK ddPTM_HeLa_Curcumin_4h_R1 1 AQPFGFIDSDTDAEEERIPATPVVIPMKK 29 2 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 AQPFGFIDS(0.359)DT(0.359)DAEEERIPAT(0.283)PVVIPMKK 43.696 0.009846 31735000 3440.3 2094.6 2872.5 2810.3 2813.5 3535 2122.8 1463.6 3926.7 2774.4 TRUE FALSE FALSE 3167.996625 2275.647891 2978.957377 2798.671723 2779.95085 2801.801152 2182.360055 1909.844902 3495.950834 2870.810193 1.103520056 0.7926849 1.037671311 0.974871738 0.968350627 0.975961824 0.760189601 0.665263383 1.217757566 1 11.48724223 -3.605815386 0.602728107 1.030907666 1.64E-12 0.585615409 0.101563681 3.013928046 0.428074441 0.015507147 2.586119669 0.000247848 3.605815386 -1.030907666 AQPFGFIDSDT(ph)DAEEERIPATPVVIPMK ddPTM_HeLa_Curcumin_4h_R1 1 AQPFGFIDSDTDAEEERIPATPVVIPMK 28 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 AQPFGFIDS(0.028)DT(0.902)DAEEERIPAT(0.07)PVVIPMK 64.013 0.00067734 17477000 1446.2 698.45 910.73 1095.8 1110.7 992.63 802.37 521.05 990.7 1033.6 TRUE FALSE FALSE 1331.731744 758.8209058 944.482455 1091.26587 1097.455628 786.7473488 824.8823427 679.9157464 882.0226886 1069.517523 1.24517057 0.709498339 0.883092081 1.020334727 1.026122157 0.735609592 0.771265851 0.635721932 0.824692134 1 10.0627444 -4.57069633 0.417465932 1.0980386 0.395788207 0.145093614 0.163583757 2.829794056 0.39676661 0.044192651 0.94158299 2.69E-05 4.57069633 -0.702250392 AQPGS(ph)PESSGQPK ddPTM_HeLa_Curcumin_4h_R1 2 AQPGSPESSGQPK 13 0 Q05GC8;Q96PN7-2;Q96PN7-3;Q96PN7-4;Q96PN7-5;Q96PN7 Q05GC8 BCAR2;TRERF1 Transcriptional-regulating factor 1 1 0 AQPGS(0.758)PES(0.223)S(0.019)GQPK;AQPGS(0.888)PES(0.072)S(0.04)GQPK ; 168.93 0.00019083 90442400 10436.6 8408.3 8765.1 9437.8 8470.5 10755.8 8871 3330.8 10414.7 8823.4 TRUE FALSE FALSE 9610.532097 9135.075985 9089.942317 9398.748884 8369.49482 8524.925837 9119.896385 4346.345587 9272.233466 9130.012493 1.052630772 1.000554599 0.995611159 1.029434395 0.916701355 0.933725539 0.998891994 0.476050344 1.015577303 1 13.15640112 -4.260579171 6.304834086 1.007872594 0.463917489 0.935123161 0.040754969 0.02439017 5.295395615 0.006575388 0.056175247 5.49E-05 4.260579171 -0.543955105 NTLQPEEALSTSDPRVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 NTLQPEEALSTSDPRVSPR 19 1 Q9BXL7 Q9BXL7 CARD11 Caspase recruitment domain-containing protein 11 1 0 NTLQPEEALSTSDPRVS(1)PR;NTLQPEEALS(0.005)T(0.016)S(0.005)DPRVS(0.973)PR ; 149.64 3.20E-05 27616600 4909.4 3730.9 4433.6 5098.4 4664.6 2907.7 1448.6 1054.08 4088.3 3771.6 TRUE FALSE FALSE 4520.81581 4053.382371 4597.913116 5077.304172 4608.977692 2304.610243 1489.243817 1375.46414 3639.823718 3902.662819 1.15839262 1.038619671 1.178147672 1.300984586 1.180982807 0.59052251 0.381596845 0.352442474 0.932651343 1 11.93024311 -5.114806899 3.40526504 1.105002292 0.381779936 0.903616731 0.101893353 0.054233278 1.159570685 0.015361509 0.044211298 7.68E-06 5.114806899 -0.723222356 down AQPSAS(ph)LGVGYR ddPTM_HeLa_Curcumin_4h_R1 1 AQPSASLGVGYR 12 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 0 AQPS(0.086)AS(0.914)LGVGYR 109.95 0.0041331 0 673.29 604.78 646.2 816.85 693.4 734.98 727.93 3621.8 863.46 904.81 TRUE FALSE FALSE 619.998386 657.0544884 670.1487405 813.4700911 685.1316579 582.5368631 748.3537567 4726.070147 768.7405983 936.2520802 0.662213093 0.701792287 0.715778106 0.86885798 0.731781186 0.622200875 0.799307978 5.047860771 0.821082927 1 9.870753209 -4.261440903 13.49577982 0.797948025 5.049119765 0.993001063 0.107738276 0.004092429 148.2397279 0.020503085 0.157659873 5.48E-05 4.261440903 4.25117174 AQPSDNAPAKGNKS(ph)PSPPDGSPAATPEIR ddPTM_HeLa_Curcumin_4h_R1 1 AQPSDNAPAKGNKSPSPPDGSPAATPEIR 29 2 O00499-6;O00499-2;O00499;O00499-9;O00499-7;O00499-4;O00499-3;O00499-5 O00499-6 BIN1 Myc box-dependent-interacting protein 1 1 0 AQPS(0.259)DNAPAKGNKS(0.714)PS(0.027)PPDGSPAATPEIR 47.616 0.0065385 11077000 1682.6 1052.1 1087.1 1264.3 863.79 1310.2 812.16 1151.7 2814.9 2135.7 TRUE FALSE FALSE 1549.420435 1143.038836 1127.388882 1259.068662 853.4898684 1038.449751 834.9470238 1502.848028 2506.112513 2209.915416 0.701122053 0.517231939 0.510150241 0.569736132 0.386209292 0.46990475 0.377818544 0.68004776 1.134030965 1 11.10977544 -8.039708028 0.543002121 0.993452306 0.465563348 0.821967701 0.101411871 0.205922217 0.14141855 0.044749064 0.027091908 9.13E-09 8.039708028 -0.527888958 AQPSSS(ph)EDELDNVFFK ddPTM_HeLa_Curcumin_4h_R1 2 AQPSSSEDELDNVFFK 16 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 0 AQPS(0.015)S(0.108)S(0.878)EDELDNVFFK;AQPSS(0.17)S(0.83)EDELDNVFFK ; 197.14 1.44E-07 9017800 2984.1 3140.2 3173.8 2916.3 3605.5 3700.7 2366.75 1083.77 2946.7 2705.2 TRUE FALSE FALSE 2747.905336 3411.624896 3291.42382 2904.233123 3562.506767 2933.133105 2433.154635 1414.206484 2623.454382 2799.205499 0.981673313 1.218783293 1.175842153 1.037520512 1.27268497 1.047844864 0.869230443 0.5052171 0.937213929 1 11.45080169 -4.340618935 2.366931923 1.046647129 0.427978324 0.723812512 0.108063383 0.214178768 1.615243338 0.016667982 0.251136066 4.56E-05 4.340618935 -0.618668805 AQPSVS(ph)LGAPYR ddPTM_HeLa_Curcumin_4h_R1 1 AQPSVSLGAPYR 12 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 0 AQPS(0.02)VS(0.98)LGAPYR 116.98 0.0038742 4783200 711.16 694.64 422.81 531.12 773.92 630.75 756.03 3633.4 601.85 735.8 TRUE FALSE FALSE 654.8709356 754.6815863 438.4797105 528.9223662 764.6915095 499.92534 777.242167 4741.206934 535.8285608 761.3689952 0.860122936 0.991216599 0.575909596 0.694699114 1.004363869 0.656613735 1.020848198 6.227213038 0.703769873 1 9.572452011 -4.261574206 6.126238859 0.882630993 6.360647806 0.990409494 0.159202821 0.008025455 1.526626289 0.021381699 0.182047162 5.48E-05 4.261574206 5.478016812 DLQS(ph)PDFTTGFHSDKIEAK ddPTM_HeLa_Curcumin_4h_R1 2 DLQSPDFTTGFHSDKIEAK 19 1 E9PDR5;E7EPI0;Q9P2D0;Q9P2D0-2 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 0 DLQS(0.969)PDFT(0.026)T(0.005)GFHSDKIEAK;DLQS(1)PDFTTGFHSDKIEAK ; 120.41 8.68E-05 151365000 12123.9 9089.2 9483.2 9576.7 8737.5 8208 4204.4 3286.4 12030.7 10370 TRUE FALSE FALSE 11164.28052 9874.829947 9834.655734 9537.074153 8633.311019 6505.568277 4322.364148 4288.408231 10710.96231 10730.35673 1.040438897 0.920270425 0.916526448 0.888793765 0.804568873 0.60627698 0.402816445 0.399651972 0.998192565 1 13.38941042 -5.113955429 0.7400273 1.0143804 0.260036821 0.972734988 0.037961764 0.12547322 0.091233253 0.007066757 0.061963659 7.69E-06 5.113955429 -0.754343579 down AQQELEEQTRR ddPTM_HeLa_Curcumin_4h_R1 2 AQQELEEQTRR 11 1 P26038 P26038 MSN Moesin 0 0 ; ; 158.06 0.00056656 53406000 6280.4 4271.2 4644.7 5351.9 5843.7 7515.7 5018.2 5710.1 6585.6 4784.6 FALSE FALSE TRUE 5783.299713 4640.383496 4816.836668 5329.755256 5774.017694 5956.859101 5158.997186 7451.083204 5863.176156 4950.864494 1.168139366 0.937287519 0.972928399 1.076530223 1.166264539 1.203195747 1.042039667 1.505006492 1.184273204 1 12.27346475 -2.082698545 1.390845467 1.0720485 200 0.632708061 0.094046933 345.6486645 1.832830897 0.014252475 218189.8167 0.008266115 2.082698545 198.9279515 SAENTILPEEETVVQNT(ph)SAGKDPLKVENSQVTVAVR ddPTM_HeLa_Curcumin_4h_R1 1 SAENTILPEEETVVQNTSAGKDPLKVENSQVTVAVR 36 2 Q15058 Q15058 KIF14 Kinesin-like protein KIF14 1 0 S(0.001)AENT(0.003)ILPEEET(0.034)VVQNT(0.478)S(0.478)AGKDPLKVENS(0.003)QVT(0.003)VAVR 40.017 0.013125 12260000 2196.6 2054 2049.5 2355.2 1955.3 1443.2 459.25 337.92 2507.7 2278 TRUE FALSE FALSE 2022.736792 2231.538608 2125.456273 2345.454806 1931.984325 1143.864052 472.135319 440.9502524 2232.611584 2357.16033 0.858124399 0.946706331 0.901702038 0.995034057 0.819623638 0.485272061 0.200298348 0.187068417 0.94716153 1 11.20283418 -5.100729736 1.868847011 0.934571861 0.1730385 0.98008221 0.042952729 0.044073144 0.291019491 0.008553892 0.032705456 7.93E-06 5.100729736 -0.761533362 down AQQQEEQGS(ph)VNDVKEEEKEEK ddPTM_HeLa_Curcumin_4h_R1 1 AQQQEEQGSVNDVKEEEKEEK 21 2 Q9Y4W2-3;Q9Y4W2-2;Q9Y4W2 Q9Y4W2-3 LAS1L Ribosomal biogenesis protein LAS1L 1 0 AQQQEEQGS(1)VNDVKEEEKEEK 47.472 0.012183 51457000 4173.6 3402.8 3514.1 3634.3 4484.6 4172.9 3321.1 1416.6 3147.7 3427.2 TRUE FALSE FALSE 3843.255156 3696.922869 3644.335637 3619.26223 4431.124074 3307.393502 3414.281128 1848.514819 2802.405185 3546.294945 1.083738159 1.042474731 1.02764595 1.020575639 1.249508048 0.93263351 0.962774157 0.521252419 0.790234661 1 11.79209681 -4.040776015 1.666747554 1.048756336 0.06742126 0.632778032 0.111369188 0.55902005 0.943496948 0.010578683 1.043349322 9.10E-05 4.040776015 -0.981335077 AQS(ph)GSDSSPEPK ddPTM_HeLa_Curcumin_4h_R1 3 AQSGSDSSPEPK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 AQS(0.994)GS(0.005)DSSPEPK;AQS(0.998)GS(0.001)DS(0.001)S(0.001)PEPK;AQS(0.532)GS(0.45)DS(0.009)S(0.009)PEPK ;; 143.93 0.00095326 32818000 14375.7 14431.8 13088.8 11979.6 10938.8 13017.6 8429.4 5395.2 13006.6 12133.3 TRUE FALSE FALSE 13237.84818 15679.22049 13573.88244 11930.03159 10808.36195 10317.60302 8665.906277 7040.171644 11579.80852 12554.93127 1.054394316 1.248849567 1.081159438 0.950226754 0.860885792 0.821796854 0.690239245 0.560749517 0.922331494 1 13.61596651 -5.021751529 0.917208288 1.047864606 0.539233455 0.797319975 0.084761528 0.291016252 0.345702417 0.013691372 0.113253169 9.51E-06 5.021751529 -0.508631151 LDS(ph)SEMDHSENEDY(ph)TMSSPLPGK ddPTM_HeLa_Curcumin_4h_R1 1 LDSSEMDHSENEDYTMSSPLPGK 23 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 2 0 LDS(0.391)S(0.253)EMDHS(0.272)ENEDY(0.667)T(0.3)MS(0.079)S(0.037)PLPGK 49.662 0.008064 5493200 1694.3 1413.2 1183.6 1632.5 1728.7 2921.6 4657.1 5734.7 2188.8 1993.5 TRUE FALSE FALSE 1560.194367 1535.350711 1227.465257 1625.745148 1708.086382 2315.627227 4787.765692 7483.183631 1948.694116 2062.773977 0.756357403 0.744313593 0.595055625 0.788135378 0.828053098 1.122579232 2.321032622 3.627728348 0.944695899 1 11.01037003 -4.48331742 1.699497911 0.834793852 3.997892876 0.984579581 0.113044929 0.064056873 0.247127945 0.020967022 0.284908326 3.29E-05 4.48331742 3.163099024 up NQGGYGGSSSSSSYGS(ph)GR ddPTM_HeLa_Curcumin_4h_R1 5 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 1 0 NQGGYGGSSSSSSYGS(1)GR;NQGGYGGSSSSSSYGS(1)GR;NQGGYGGSSSSSSYGS(1)GR;NQGGYGGSSSSSSYGS(1)GR;NQGGYGGSSSSSSYGS(1)GR ;;;; 312.63 1.87E-113 109605300 9994.56 9192.13 7790.04 8413.52 9136.15 12835.33 12402.81 11880.41 9473.83 7303.04 TRUE FALSE FALSE 9203.48003 9986.656758 8078.745735 8378.707084 9027.207378 10173.13787 12750.79947 15502.69232 8434.574551 7556.820096 1.217903816 1.321542214 1.069066834 1.108760957 1.194577516 1.346219408 1.687323412 2.051483576 1.116153944 1 12.88356356 -4.480524275 1.13610218 1.119252425 2.310563965 0.927558349 0.082853809 0.259231189 0.348914187 0.01621591 0.332752458 3.31E-05 4.480524275 1.19131154 up ILEDHGS(ph)PAGEIDDEDKDKDETETVK ddPTM_HeLa_Curcumin_4h_R1 1 ILEDHGSPAGEIDDEDKDKDETETVK 26 2 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;H0YBA1 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 0 ILEDHGS(0.999)PAGEIDDEDKDKDETETVK 47.104 0.0088272 10106000 2032.9 1239.1 1635.5 1737.2 1496.5 1168.7 544 304.45 1690.2 1587.6 TRUE FALSE FALSE 1871.99382 1346.202283 1696.113069 1730.011927 1478.655215 926.298446 559.2631759 397.2754035 1504.789289 1642.768982 1.13953565 0.819471452 1.032472056 1.053107251 0.900099303 0.563864095 0.340439333 0.241832788 0.916007853 1 10.6819139 -5.096933267 1.462717837 1.046087712 0.236428885 0.907513137 0.089997426 0.085302851 0.327911825 0.013533777 0.062924398 8.00E-06 5.096933267 -0.809658827 down DSAAPS(ph)PIPGADNLSADPVVSPPTSIPFK ddPTM_HeLa_Curcumin_4h_R1 1 DSAAPSPIPGADNLSADPVVSPPTSIPFK 29 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 0 DS(0.09)AAPS(0.9)PIPGADNLS(0.01)ADPVVSPPTSIPFK 82.403 3.28E-06 10955000 8799.2 7139.1 7034.2 7382.8 6106.7 6131.6 3103.7 2017.3 8657.5 6829.9 TRUE FALSE FALSE 8102.734035 7756.171993 7294.89364 7352.25193 6033.881591 4859.837043 3190.781469 2632.365483 7707.79391 7067.238517 1.146520528 1.097482698 1.032212741 1.040328823 0.853782079 0.687657142 0.451489144 0.372474408 1.090637297 1 12.78693088 -5.083946347 1.087326738 1.073280797 0.325249869 0.977033063 0.040232787 0.094599895 0.178374204 0.00914763 0.057810975 8.24E-06 5.083946347 -0.748030928 down AQS(ph)SPAAPASLSAPEPASQAR ddPTM_HeLa_Curcumin_4h_R1 2 AQSSPAAPASLSAPEPASQAR 21 0 J3KPH8;Q8WUI4-3;Q8WUI4-4;Q8WUI4;Q8WUI4-7;Q8WUI4-6;Q8WUI4-5;Q8WUI4-8;Q8WUI4-10;H0YI15 J3KPH8 HDAC7 Histone deacetylase;Histone deacetylase 7 1 0 AQS(0.499)S(0.499)PAAPASLS(0.001)APEPASQAR;AQS(0.37)S(0.37)PAAPAS(0.24)LS(0.021)APEPASQAR ; 270.37 7.36E-60 88763100 6030.2 4847.3 5233.4 4967.8 5508.1 7415 5426.5 6659.2 5801.2 6033.7 TRUE FALSE FALSE 5552.903307 5266.279013 5427.354408 4947.24456 5442.419505 5877.045416 5578.752985 8689.559425 5164.822874 6243.370626 0.889407924 0.843499342 0.86929877 0.792399628 0.871711745 0.941325731 0.893548264 1.391805796 0.827249123 1 12.6081094 -4.2597881 24.8961009 0.916048801 1.391805964 0.843594268 0.064414291 46.43091152 699964.7658 0.010337457 0.088114491 5.50E-05 4.2597881 0.475757163 AQS(ph)SPASATFPVSVQEPPTKPR ddPTM_HeLa_Curcumin_4h_R1 2 AQSSPASATFPVSVQEPPTKPR 22 1 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 0 AQS(0.769)S(0.225)PAS(0.006)ATFPVSVQEPPTKPR;AQS(0.742)S(0.234)PAS(0.024)ATFPVSVQEPPTKPR ; 146.72 6.06E-06 177022000 1385.58 1138.21 1092.34 1041.2 1112.49 1689.14 1117.68 1634.67 1072.88 990.38 TRUE FALSE FALSE 1275.909881 1236.591801 1132.823081 1036.89179 1099.224283 1338.793323 1149.039093 2133.073358 955.1877482 1024.795631 1.245038369 1.206671616 1.105413652 1.011803484 1.0726278 1.306400303 1.121237306 2.081462189 0.932076327 1 10.00112052 -4.26124988 24.94598803 1.12643449 2.08146248 0.87280517 0.110976422 3.827390909 503455.4577 0.015746624 0.122119817 5.48E-05 4.26124988 0.95502799 AQS(ph)TDS(ph)LGTSGSLQSK ddPTM_HeLa_Curcumin_4h_R1 1 AQSTDSLGTSGSLQSK 16 0 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 2 0 AQS(0.687)T(0.312)DS(0.983)LGT(0.005)S(0.001)GS(0.002)LQS(0.01)K 120.74 0.0021319 14915000 4142.7 3103.2 4269.3 4210.2 3983.8 4777.3 3118.9 3302.4 3808.6 3945.8 TRUE FALSE FALSE 3814.800924 3371.42678 4427.524014 4192.779308 3936.295787 3786.434129 3206.40794 4309.286558 3390.806109 4082.916256 0.934332395 0.82573988 1.084402357 1.026907986 0.964089278 0.927384715 0.785322975 1.055443288 0.830486323 1 11.99538426 -6.254255646 0.007372596 1.898506428 4.69E-07 0 0.10182958 12011.85117 35.33942942 4463.427452 4635.753386 5.57E-07 6.254255646 -1.898505959 AQS(ph)YPDNHQEFSDYDNPIFEK ddPTM_HeLa_Curcumin_4h_R1 1 AQSYPDNHQEFSDYDNPIFEK 21 0 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 0 AQS(0.969)Y(0.031)PDNHQEFSDYDNPIFEK 131.94 1.28E-05 9877000 4605.2 3432.1 4185.6 3951 3807.2 5218.5 3721.2 7829.7 5293.2 4135.3 TRUE FALSE FALSE 4240.693561 3728.755431 4340.722018 3934.651809 3761.801627 4136.124275 3825.606857 10216.93949 4712.549203 4279.001367 0.991047489 0.871407862 1.014424078 0.919525719 0.879130737 0.966609711 0.894041981 2.387692503 1.101319864 1 12.06305842 -4.259608228 24.99985316 0.968756209 2.38769298 0.975199835 0.068302049 14.2255658 194199.1422 0.007953983 0.068629632 5.50E-05 4.259608228 1.418936771 AQSEGRPCEYNSR ddPTM_HeLa_Curcumin_4h_R1 4 AQSEGRPCEYNSR 13 1 O00622 O00622 CYR61 Protein CYR61 0 0 ;;; ;;; 106.54 0.0014681 17687200 4285.6 4111.61 4581.97 4878.48 4799.21 6296.8 4566.69 2647.32 5847.12 3627.31 FALSE FALSE TRUE 3946.390238 4466.999247 4751.781839 4858.294142 4741.982555 4990.7727 4694.819031 3454.475681 5205.705565 3753.358753 1.051428999 1.190133835 1.266007902 1.294385766 1.263397098 1.329681768 1.250831413 0.92036917 1.386945908 1 11.87396648 -7.255144034 2.532312846 1.020939104 1.232804935 0 0.157425882 0.190714129 2.34796534 0.018634712 0.022132671 5.56E-08 7.255144034 0.21186583 AQSGSDS(ph)SPEPK ddPTM_HeLa_Curcumin_4h_R1 4 AQSGSDSSPEPK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 AQS(0.002)GS(0.038)DS(0.48)S(0.48)PEPK;AQS(0.004)GS(0.052)DS(0.801)S(0.143)PEPK;AQS(0.003)GS(0.026)DS(0.486)S(0.486)PEPK;AQSGS(0.001)DS(0.911)S(0.087)PEPK ;;; 136.33 0.0016559 44977000 19715.7 28604 20455.7 16983.1 17028.6 15018.3 10600.8 6189.57 15659.5 18395.3 TRUE FALSE FALSE 18155.18154 31076.4023 21213.80624 16912.82843 16825.54507 11903.33529 10898.22992 8076.7414 13941.69203 19034.53531 0.953802194 1.63263257 1.114490367 0.888533823 0.883948297 0.625354657 0.572550353 0.424320388 0.732441943 1 14.21633173 -5.271182563 1.347090851 1.041250982 0.471764525 0.532905979 0.219350497 0.287394093 0.951486857 0.032556259 0.132071368 5.36E-06 5.271182563 -0.569486456 AQSGSDSS(ph)PEPK ddPTM_HeLa_Curcumin_4h_R1 1 AQSGSDSSPEPK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 AQSGSDS(0.464)S(0.536)PEPK 186.29 3.12E-05 22438000 6039.7 9954.1 6835.5 5049.5 5038.8 4646.3 2889 1564.2 4258.4 5390.3 TRUE FALSE FALSE 5561.651372 10814.48805 7088.829643 5028.606507 4978.715601 3682.605005 2970.057565 2041.117379 3791.264174 5577.612524 0.997138354 1.938909884 1.270943367 0.90156971 0.89262486 0.66024755 0.532496216 0.365948221 0.679728855 1 12.445432 -5.212223387 1.312305262 1.095248976 0.413620343 0.448771965 0.311204593 0.375928919 1.157685559 0.047648682 0.211544197 6.13E-06 5.212223387 -0.681628633 AQSLVIS(ph)PPAPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 AQSLVISPPAPSPR 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 2 0 AQS(0.002)LVIS(0.998)PPAPS(1)PR 93.342 0.004913 0 1474.7 1326.1 1497.1 1977.2 1607.1 3244.5 3408.7 883.53 2164.1 1200.8 TRUE FALSE FALSE 1357.975939 1440.722175 1552.583843 1969.01887 1587.936382 2571.554127 3504.338948 1152.91423 1926.703644 1242.527711 1.092914007 1.15950909 1.249536594 1.584688095 1.277988707 2.069615112 2.82033062 0.927878083 1.550632334 1 10.27906231 -5.859626158 1.014122925 1.050674343 1.988751425 0.22851055 0.484392864 0.372781186 0.74537417 0.071631251 0.20391444 1.38E-06 5.859626158 0.938077082 AQSLVISPPAPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 AQSLVISPPAPSPR 14 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 AQS(0.005)LVIS(0.014)PPAPS(0.982)PR;AQSLVISPPAPS(1)PR ; 95.662 0.0072043 42072000 2966.9 2226.3 2793.8 2823.5 2906.5 4142.8 3287.7 2049.13 3879.4 3119.3 TRUE FALSE FALSE 2732.066734 2418.731452 2897.340686 2811.817105 2871.841886 3283.536581 3379.944014 2673.900304 3453.839526 3227.695443 0.84644502 0.74936793 0.89764996 0.871153166 0.889749958 1.017300622 1.047169435 0.82842398 1.070063637 1 11.65628874 -3.959111323 16.03476922 0.918613052 0.420308009 0.079382558 0.096542323 3872360.313 41762820.66 0.013304774 56745183.95 0.000109872 3.959111323 -0.498305043 AQSNGSGNGS(ph)DSEMDTSSLER ddPTM_HeLa_Curcumin_4h_R1 3 AQSNGSGNGSDSEMDTSSLER 21 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 0 AQSNGS(0.016)GNGS(0.98)DS(0.004)EMDTSSLER;AQSNGSGNGS(0.996)DS(0.004)EMDTSSLER;AQSNGS(0.014)GNGS(0.974)DS(0.012)EMDTSSLER ;; 168.3 1.84E-08 42021000 3780.4 3052.77 3201.76 3318.66 3639.56 4106.5 2880.64 1322.26 3935 3283.93 TRUE FALSE FALSE 3481.177351 3316.637836 3320.420042 3304.928264 3596.160624 3254.76561 2961.463006 1725.410987 3503.340345 3398.046323 1.02446436 0.976042561 0.977155614 0.972596589 1.058302413 0.957834385 0.871519316 0.507765587 1.030986635 1 11.7304898 -4.143783008 1.624578318 1.006063987 0.215003463 0.966277911 0.027760613 0.160936125 0.319185031 0.003905038 0.217836669 7.18E-05 4.143783008 -0.791060523 AQSPS(ph)YVISTGVSPSR ddPTM_HeLa_Curcumin_4h_R1 1 AQSPSYVISTGVSPSR 16 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 0 AQS(0.33)PS(0.664)YVIS(0.001)T(0.001)GVS(0.001)PS(0.002)R 130.95 0.00046017 6602200 2137.1 1699.5 1345.7 1734.6 1663.7 1751.6 1084.4 677.32 1812 1691.9 TRUE FALSE FALSE 1967.94628 1846.397207 1395.572826 1727.422685 1643.861464 1388.298415 1114.825345 883.83175 1613.228133 1750.693399 1.124095333 1.05466623 0.797154331 0.986707716 0.938977359 0.792999172 0.63679074 0.50484668 0.921479532 1 10.77371073 -4.100004444 0.513405455 1.054961623 5.78E-11 0.780003803 0.085876244 1.354824256 0.213488531 0.017449403 0.888218878 7.94E-05 4.100004444 -1.054961622 AQSPVS(ph)GPNVAHLTDGATLNDR ddPTM_HeLa_Curcumin_4h_R1 1 AQSPVSGPNVAHLTDGATLNDR 22 0 Q5THJ4-2;Q5THJ4 Q5THJ4-2 VPS13D Vacuolar protein sorting-associated protein 13D 1 0 AQS(0.324)PVS(0.676)GPNVAHLTDGATLNDR 95.646 9.84E-05 6723000 549.24 311.13 483.11 292.4 384.86 580.69 287.28 174.06 636.21 471.84 TRUE FALSE FALSE 505.7670744 338.0226908 501.0144816 291.1901263 380.2707959 460.2483483 295.3403036 227.1300927 566.4193547 488.2364049 1.035906109 0.692334057 1.026171905 0.596412155 0.778866123 0.942675195 0.604912499 0.465205156 1.160133388 1 8.931436062 -3.817910605 0.272863795 1.042479983 1.71E-14 0.558174691 0.147337539 6.180874909 0.289291997 0.075910928 2.250069828 0.000152086 3.817910605 -1.042479983 AQSS(ph)PAAPASLSAPEPASQAR ddPTM_HeLa_Curcumin_4h_R1 2 AQSSPAAPASLSAPEPASQAR 21 0 J3KPH8;Q8WUI4-3;Q8WUI4-4;Q8WUI4;Q8WUI4-7;Q8WUI4-6;Q8WUI4-5;Q8WUI4-8;Q8WUI4-10;H0YI15 J3KPH8 HDAC7 Histone deacetylase;Histone deacetylase 7 1 0 AQS(0.156)S(0.844)PAAPASLSAPEPASQAR;AQS(0.093)S(0.907)PAAPASLSAPEPASQAR ; 294.28 1.30E-87 202389000 3177.7 2599.8 2866.3 2557.1 2943.8 3348.5 2984.09 3802.1 3120.4 2780.6 TRUE FALSE FALSE 2926.181692 2824.515128 2972.527599 2546.519398 2908.697108 2653.983355 3067.815534 4961.342787 2778.099927 2877.225643 1.017015019 0.98168009 1.033122865 0.885060719 1.010938129 0.922410573 1.066240857 1.724349565 0.96554816 1 11.49046265 -4.264464623 4.027305025 0.994775587 1.786847824 0.959756604 0.045505745 0.028869076 0.982526326 0.005877212 0.06613185 5.44E-05 4.264464623 0.792072237 AQST(ph)DSLGT(ph)SGSLQSK ddPTM_HeLa_Curcumin_4h_R1 1 AQSTDSLGTSGSLQSK 16 0 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 2 0 AQS(0.18)T(0.819)DS(0.485)LGT(0.463)S(0.048)GS(0.004)LQS(0.001)K 132.14 0.0016311 11619000 2995.5 3155.2 3609.8 3445 3658.6 3933.8 2631.5 2856.5 3885.2 3475.6 TRUE FALSE FALSE 2758.403014 3427.921429 3743.582364 3430.745503 3614.973585 3117.885537 2705.332808 3727.4337 3459.00328 3596.376841 0.766994989 0.953159688 1.040931618 0.953944944 1.005170966 0.866951845 0.752238413 1.036441359 0.961802234 1 11.81232848 -1.50750815 15.66635213 0.909451649 1.138101592 0 0.102088846 0 0 0.015412484 0 0.031080776 1.50750815 0.228649943 AQST(ph)DSLGTSGSLQSK ddPTM_HeLa_Curcumin_4h_R1 1 AQSTDSLGTSGSLQSK 16 0 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 0 AQS(0.065)T(0.743)DS(0.192)LGTSGSLQSK 279.19 6.64E-65 65038000 3310.3 2825.2 2770.3 3163.9 2917.3 3009.2 2959.7 5789.4 3236 2954.3 TRUE FALSE FALSE 3048.286262 3069.397699 2872.969755 3150.80862 2882.513103 2385.057999 3042.741216 7554.561409 2881.018896 3056.961705 0.99716207 1.00406809 0.939812151 1.030699408 0.942933992 0.78020539 0.995348163 2.471264653 0.942445203 1 11.57788276 -4.26165644 7.717741748 0.978276064 2.485529714 0.97740753 0.068916492 0.009779819 6.214202903 0.009644771 0.076688486 5.47E-05 4.26165644 1.50725365 AQSTDS(ph)LGTSGSLQSK ddPTM_HeLa_Curcumin_4h_R1 1 AQSTDSLGTSGSLQSK 16 0 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 0 AQSTDS(0.482)LGT(0.411)S(0.106)GS(0.001)LQSK 300.87 9.82E-95 12451000 3517.9 2352.3 3555.9 3505.9 3134.2 4340.2 3661.9 1140.1 3589.4 3086.5 TRUE FALSE FALSE 3239.454503 2555.62233 3687.684782 3491.393515 3096.826712 3439.993596 3764.643059 1487.711242 3195.6518 3193.755645 1.014308815 0.800193444 1.154654642 1.093193689 0.969650486 1.077099809 1.178751125 0.465818743 1.000593707 1 11.64103822 -4.251157362 24.99215928 1.019549672 0.465818437 0.734661544 0.101838113 555.3984461 1349962.646 0.013291072 0.248281844 5.61E-05 4.251157362 -0.553731235 AQSYPDNHQEFS(ph)DYDNPIFEK ddPTM_HeLa_Curcumin_4h_R1 1 AQSYPDNHQEFSDYDNPIFEK 21 0 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 0 AQS(0.035)Y(0.001)PDNHQEFS(0.937)DY(0.027)DNPIFEK 71.969 0.0013059 65865000 2550 2110.8 2112.2 2248.7 2470.5 2494.4 2197.5 4410.3 2860.6 2672.9 TRUE FALSE FALSE 2348.164809 2293.248146 2190.47999 2239.395475 2441.040901 1977.033322 2259.155936 5754.980167 2546.799337 2765.783076 0.849005415 0.829149678 0.791992694 0.809678638 0.882585812 0.714818649 0.816823255 2.080777852 0.920823964 1 11.43347229 -4.259586509 24.99959467 0.88075781 2.080778255 0.955057254 0.080033692 30.60609379 412915.3575 0.014233358 0.123371724 5.50E-05 4.259586509 1.200020445 AQT(ph)APTKTS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 AQTAPTKTSPR 11 1 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 2 0 AQT(1)APTKT(0.042)S(0.958)PR 118.52 0.018606 2336600 1570.8 1605.8 1451.9 1416.1 2016.4 3055.1 2774.7 288.83 2085.9 1856.3 TRUE FALSE FALSE 1446.469522 1744.598197 1505.708691 1410.240553 1992.355747 2421.437822 2852.550614 376.8929374 1857.081989 1920.806287 0.753053305 0.908263477 0.783894087 0.734191971 1.037249701 1.260636139 1.485079799 0.196216006 0.966824193 1 10.90749632 -5.6563457 9.172363257 0.86521056 1.050337933 0.030655177 0.3208576 0.604231182 48.48149871 0.043610562 0.087296808 2.21E-06 5.6563457 0.185127373 GPAFNMAS(ph)PESDFGINLK ddPTM_HeLa_Curcumin_4h_R1 2 GPAFNMASPESDFGINLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GPAFNMAS(0.885)PES(0.115)DFGINLK;GPAFNMAS(0.98)PES(0.02)DFGINLK ; 81.317 0.0069299 130171000 4082.5 3075.73 3245.25 3639.64 3733.27 7051.6 6687.5 7174.4 3854.59 2983.39 TRUE FALSE FALSE 3759.365817 3341.582396 3365.52182 3624.580134 3688.753194 5589.018672 6875.133252 9361.841533 3431.751121 3087.06258 1.21778089 1.082447248 1.090202007 1.174119422 1.194907164 1.810464973 2.227079326 3.032605038 1.111655832 1 11.59201901 -4.468722941 0.966942675 1.096229718 3.662629527 0.984829033 0.077856891 0.144749215 0.127800928 0.014981276 0.356738159 3.40E-05 4.468722941 2.566399809 up AQTK(ac)APPKPAR ddPTM_HeLa_Curcumin_4h_R1 2 AQTKAPPKPAR 11 2 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2;S4R349;S4R3C2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 1 ; AQTK(1)APPKPAR;AQTK(1)APPKPAR 99.752 0.0024102 4692200 1985.17 2139.03 1857.7 1945.14 2193.4 2643.6 2245.4 1114.18 2591.2 2174 FALSE TRUE FALSE 1828.0417 2323.918222 1926.547996 1937.091526 2167.245138 2095.28756 2308.399881 1453.888353 2306.951843 2249.546338 0.812626826 1.033060836 0.856416231 0.861103189 0.963414312 0.931426717 1.026162405 0.646302914 1.025518703 1 11.13541837 -7.712804933 0.011770847 1.823472919 2.39E-06 0.134773831 0.109017298 2021.021571 17.89652399 1398.077264 1372.405774 1.94E-08 7.712804933 -1.823470526 AQTLPTSVVTITSESS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 1 AQTLPTSVVTITSESSPGK 19 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 AQTLPTSVVTITSES(0.193)S(0.807)PGK 188.71 8.21E-10 23296000 2543.6 2455.5 2417.7 2637.5 2748.3 3533.2 2605.2 1059.9 2667.4 2166.5 TRUE FALSE FALSE 2342.271376 2667.742479 2507.302089 2626.586724 2715.528317 2800.374493 2678.2949 1383.058631 2374.792894 2241.785714 1.044823937 1.190007797 1.118439677 1.171649327 1.211323768 1.249171353 1.194714947 0.616945064 1.059330907 1 11.13043267 -7.455458587 5.485612722 1.019263201 1.123269981 0.030433614 0.171447672 0.452672563 25.0683459 0.028393879 0.031966343 3.50E-08 7.455458587 0.10400678 AQTLPTSVVTITSESS(ph)PGKR ddPTM_HeLa_Curcumin_4h_R1 3 AQTLPTSVVTITSESSPGKR 20 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 AQTLPTSVVTITS(0.002)ES(0.005)S(0.994)PGKR;AQTLPTSVVTIT(0.006)S(0.197)ES(0.387)S(0.411)PGKR;AQTLPTSVVTIT(0.02)S(0.009)ES(0.132)S(0.839)PGKR ;; 243.76 3.81E-34 4925144000 6577.46 5603.56 5702.49 6444.5 5861.42 8055.5 6227.57 3019.22 6785.3 5618.57 TRUE FALSE FALSE 6056.8471 6087.906757 5913.829296 6417.834367 5791.526395 6384.698496 6402.298854 3939.766279 6040.969566 5813.814889 1.041802537 1.047144925 1.017202888 1.103893827 0.996166288 1.098194321 1.101221655 0.677655955 1.039071536 1 12.50526942 -4.254936767 24.99332139 1.035108661 0.677655793 0.882235277 0.040444115 193.7144744 744537.465 0.005850997 0.075197557 5.56E-05 4.254936767 -0.357452868 AQTPPGPS(ph)LSGSK ddPTM_HeLa_Curcumin_4h_R1 1 AQTPPGPSLSGSK 13 0 Q9UQ35;Q9UQ35-2;I3L4D8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 AQT(0.349)PPGPS(0.52)LS(0.012)GS(0.119)K 103.11 0.0055243 81966000 3771.4 3393.8 3487.1 3623.1 4166.3 5054.6 5815.5 5496.1 3339.9 3689.1 TRUE FALSE FALSE 3472.88971 3687.14495 3616.334994 3608.108572 4116.619594 4006.218983 5978.667278 7171.835589 2973.521326 3817.29595 0.909777433 0.965904923 0.947355154 0.945200115 1.07841248 1.049491324 1.56620481 1.878773792 0.778960124 1 11.89833533 -4.591667091 1.685653419 0.959827087 1.965193179 0.948154583 0.073426431 0.055323815 0.235813562 0.007225797 0.07303497 2.56E-05 4.591667091 1.005366092 AQTPPGPSLSGSKS(ph)PCPQEK ddPTM_HeLa_Curcumin_4h_R1 2 AQTPPGPSLSGSKSPCPQEK 20 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 AQTPPGPS(0.045)LS(0.206)GS(0.206)KS(0.543)PCPQEK;AQTPPGPS(0.026)LS(0.059)GS(0.2)KS(0.715)PCPQEK ; 57.768 0.008833 1086870000 7973.4 5980.5 7123.3 7339.8 6797.1 7650.2 5321.3 3516.7 7745.3 6681.7 TRUE FALSE FALSE 7342.296977 6497.427771 7387.295764 7309.429852 6716.049022 6063.462284 5470.601356 4588.925641 6895.659968 6913.888578 1.061963451 0.939764605 1.068471914 1.057209669 0.971385198 0.876997397 0.791248123 0.663725715 0.997363479 1 12.75528164 -4.740089584 1.12295771 1.028026822 0.627046572 0.901514935 0.039113348 0.178141886 0.297580035 0.006162987 0.068702379 1.82E-05 4.740089584 -0.40098025 AQTSTDAPTSAPSAPPST(ph)PTPSAGKR ddPTM_HeLa_Curcumin_4h_R1 1 AQTSTDAPTSAPSAPPSTPTPSAGKR 26 1 Q8IWZ8;B4DVK3;V9GZ08;Q8IWZ8-2 Q8IWZ8 SUGP1 SURP and G-patch domain-containing protein 1 1 0 AQTSTDAPTSAPS(0.002)APPS(0.223)T(0.744)PT(0.029)PS(0.001)AGKR 138.78 1.26E-09 0 1440 1033.6 1213.6 1180.5 1408.6 2187.7 2021.8 1283 1588.8 1216.4 TRUE FALSE FALSE 1326.022481 1122.939778 1258.577084 1175.615404 1391.803365 1733.94636 2078.526267 1674.180794 1414.512615 1258.669809 1.053510993 0.89216391 0.99992633 0.934014143 1.105773218 1.377602248 1.651367381 1.330119131 1.123815479 1 10.29768415 -5.250971988 2.833536174 1.007437971 1.49478603 0.821764525 0.094931025 0.066251778 1.059076806 0.011745498 0.032403365 5.61E-06 5.250971988 0.487348059 AQVARPGGDTIFGK ddPTM_HeLa_Curcumin_4h_R1 1 AQVARPGGDTIFGK 14 1 D6RC06;D6REP8;D6RE99;D6RD60;P49773 D6RC06 HINT1 Histidine triad nucleotide-binding protein 1 0 0 118.52 0.00032751 12329000 4013.5 3075.3 3609 3306.5 3347.1 5420.4 3488.6 3843.7 3910.3 3706.7 FALSE FALSE TRUE 3695.82724 3341.115229 3742.752715 3292.818579 3307.188019 4296.14794 3586.480727 5015.626436 3481.349873 3835.507549 0.963582314 0.8711012 0.975816803 0.858509216 0.862255641 1.12009894 0.935073307 1.307682587 0.907663413 1 11.90520179 -2.108002861 1.459123229 0.962008922 200 0.641710536 0.079279612 409.5681255 1.914077877 0.011061081 271819.4603 0.00779825 2.108002861 199.0379911 AQVARPGGDTIFGK(ac)IIR ddPTM_HeLa_Curcumin_4h_R1 2 AQVARPGGDTIFGKIIR 17 2 D6RC06;D6REP8;D6RE99;D6RD60;P49773 D6RC06 HINT1 Histidine triad nucleotide-binding protein 1 0 1 ; AQVARPGGDTIFGK(1)IIR;AQVARPGGDTIFGK(1)IIR 114.54 0.0001368 12266800 2963.27 1940.29 2500.35 2218.55 2064.47 3593.7 2851.6 2436.1 2457.01 2496.28 FALSE TRUE FALSE 2728.724053 2108.000022 2593.015171 2209.370228 2039.852544 2848.326111 2931.608221 3178.855676 2187.48215 2583.025544 1.056406143 0.816097242 1.003867413 0.855341997 0.789714429 1.102709231 1.134951309 1.230671405 0.846868183 1 11.3348462 -5.013954596 19.92597155 0.981075976 1.166817227 0.466589435 0.104548068 35.46408268 50644.82453 0.015067253 0.040447888 9.68E-06 5.013954596 0.185741251 AQVLATIHGHAGAFPAAGDAGEGAPGGGS(ph)SPER ddPTM_HeLa_Curcumin_4h_R1 1 AQVLATIHGHAGAFPAAGDAGEGAPGGGSSPER 33 0 Q86WR7;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 0 AQVLATIHGHAGAFPAAGDAGEGAPGGGS(0.795)S(0.205)PER 95.47 4.48E-11 33582000 514.6 414.23 531.48 425.5 588.41 539.85 526.15 334.55 949.28 471 TRUE FALSE FALSE 473.868867 450.0341954 551.1771163 423.7393937 581.3935951 427.8790246 540.9123529 436.5527549 845.146359 487.3672149 0.972303537 0.923398582 1.130927767 0.869445832 1.192927175 0.877939696 1.109866106 0.895736811 1.734105892 1 8.928865394 AQVLATIHGHAGAFPAAGDAGEGAPGGGSS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 AQVLATIHGHAGAFPAAGDAGEGAPGGGSSPER 33 0 Q86WR7;D3DRR9 Q86WR7 PROSER2;C10orf47 Proline and serine-rich protein 2 1 0 AQVLATIHGHAGAFPAAGDAGEGAPGGGS(0.373)S(0.627)PER 85.591 3.04E-08 20377000 1710.1 1579.3 1391.1 1758.6 1656.2 2014.9 1616.2 1427.9 2103.5 1370.1 TRUE FALSE FALSE 1574.743781 1715.807655 1442.65539 1751.323379 1636.450897 1596.987027 1661.546222 1863.260137 1872.751313 1417.710873 1.110765115 1.210266273 1.017594925 1.235317731 1.154290997 1.126454666 1.171992297 1.314273716 1.320968435 1 10.46934763 -1.000000076 0.022631084 1.90E-09 2.656702997 0 0.119128882 1075.623081 1.893182039 79.58098173 154.314769 0.099999983 1.000000076 2.656702995 AQVPGPLT(ph)PEMEAR ddPTM_HeLa_Curcumin_4h_R1 2 AQVPGPLTPEMEAR 14 0 Q9H8Y5;B8ZZS4 Q9H8Y5 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 0 AQVPGPLT(1)PEMEAR;AQVPGPLT(1)PEMEAR ; 174.24 0.00055744 66739000 5933.9 4695.8 5191.4 5642.4 5173.2 6611.4 4328.4 2361.6 5405.9 5032.6 TRUE FALSE FALSE 5464.225554 5101.684028 5383.797851 5619.053244 5111.512969 5240.121114 4449.843255 3081.640969 4812.886295 5207.482475 1.049302725 0.979683379 1.033858083 1.079034499 0.981570844 1.006267643 0.854509502 0.591771741 0.924225154 1 12.34637036 -4.268788433 1.574480747 1.023571415 0.429140974 0.899106444 0.042520403 0.151729395 0.350274065 0.004325482 0.137799916 5.39E-05 4.268788433 -0.594430441 AQYDELAR ddPTM_HeLa_Curcumin_4h_R1 2 AQYDELAR 8 0 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 0 0 ; ; 136.27 0.0010556 36667000 10883.7 8805.2 9388.3 9413.4 9470.9 12500 9481.9 6406.8 11326.9 9164.2 FALSE FALSE TRUE 10022.24366 9566.282253 9736.238657 9374.449845 9357.965703 9907.359096 9747.936595 8360.203827 10084.36741 9482.655268 1.056902669 1.008818942 1.026741812 0.988589122 0.986850775 1.044787437 1.027975427 0.881631103 1.063453972 1 13.21107537 -4.259987227 24.63611847 1.022188779 0.881631047 0.732992337 0.025537407 42.44602343 720015.3882 0.003716432 0.031315646 5.50E-05 4.259987227 -0.140557732 ARDEWDR ddPTM_HeLa_Curcumin_4h_R1 1 ARDEWDR 7 1 Q2TAM9 Q2TAM9 TUSC1 Tumor suppressor candidate gene 1 protein 0 0 96.19 0.008952 0 1658.6 1624.3 1325.1 1701.8 1366.8 2093.3 1525.7 1222.9 1915.6 1444.9 FALSE FALSE TRUE 1527.32006 1764.697254 1374.209372 1694.758403 1350.501803 1659.125984 1568.507036 1595.75658 1705.463473 1495.110167 1.021543491 1.180312523 0.919135861 1.13353413 0.903279124 1.109701492 1.049091278 1.067317055 1.140694184 1 10.54603608 -7.505194158 21.22686377 1.0095042 1.050132525 0 0.091528522 55.85147404 67044.01567 0.012851159 0.013777352 3.12E-08 7.505194158 0.040628324 AREEAERELER ddPTM_HeLa_Curcumin_4h_R1 1 AREEAERELER 11 2 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 84.31 0.0090288 86521000 2460.1 1740.4 2088.2 2303.8 2225.3 2732.3 1956 1905.3 2820.5 2143.9 FALSE FALSE TRUE 2265.380489 1890.832421 2165.590529 2294.267486 2198.764751 2165.590181 2010.880096 2486.217199 2511.098207 2218.400365 1.021177477 0.852340475 0.976194632 1.034199021 0.991148751 0.976194475 0.906454997 1.120725203 1.131940945 1 11.11530404 AREEEEQK(ac)EGGDGAAGDPKK ddPTM_HeLa_Curcumin_4h_R1 2 AREEEEQKEGGDGAAGDPKK 20 3 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 0 1 ; AREEEEQK(1)EGGDGAAGDPKK;AREEEEQK(1)EGGDGAAGDPKK 102.03 0.00036586 4133900 1704.96 2107.04 2025.76 1832.8 2625.9 2835.26 2011.52 2383.71 3518.9 1647.17 FALSE TRUE FALSE 1570.010617 2289.163149 2100.836448 1825.216359 2594.587858 2247.195116 2067.957837 3110.492206 3132.885474 1704.409035 0.921146617 1.343083205 1.232589364 1.070879303 1.522280042 1.318459988 1.213299035 1.824968151 1.838106587 1 10.73505589 -1 0.218447511 0.916733267 4.810829351 0 0.327787241 23.88854248 0.284960331 0.129946811 33.02868679 0.1 1 3.894096084 AREEEEQKEGGDGAAGDPK ddPTM_HeLa_Curcumin_4h_R1 1 AREEEEQKEGGDGAAGDPK 19 2 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 0 0 65.175 0.0060659 2186100 2249.5 1948.6 2006.2 2375.2 2577.6 2487.1 2464.4 1881.7 2181.9 1936.9 FALSE FALSE TRUE 2071.449701 2117.028301 2080.551537 2365.372052 2546.863803 1971.247425 2533.544431 2455.421668 1942.551029 2004.207131 1.033550709 1.056292171 1.038092074 1.180203391 1.270758778 0.983554741 1.264113071 1.225133685 0.969236662 1 10.9688159 -6.288817091 4.370293742 1.020647832 1.18354188 0.531852139 0.077698403 0.124707975 5.791779663 0.011211169 0.017839027 5.14E-07 6.288817091 0.162894047 AREEEEQKEGGDGAAGDPKK ddPTM_HeLa_Curcumin_4h_R1 1 AREEEEQKEGGDGAAGDPKK 20 3 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 0 0 40.085 0.015053 3208600 5023 3350.6 4290.1 4340.6 3634.4 4819.6 4017.3 4361 5185.3 4798 FALSE FALSE TRUE 4625.42425 3640.210934 4449.09488 4322.639747 3591.062154 3819.960632 4130.014626 5690.648824 4616.485563 4964.730143 0.93165673 0.733214259 0.896140324 0.870669628 0.723314672 0.76941959 0.831870919 1.146215134 0.929856292 1 12.27749959 -7.495514292 5.273992252 0.970913072 0.845143599 0.141134431 0.113997111 0.221907991 15.26020164 0.019590668 0.021597868 3.20E-08 7.495514292 -0.125769473 AREES(ph)WGPPR ddPTM_HeLa_Curcumin_4h_R1 2 AREESWGPPR 10 1 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 0 AREES(1)WGPPR;AREES(1)WGPPR ; 89.356 0.0088947 9960300 2753 2501.2 3100.2 2575.4 2565.8 3419.7 2669.9 1877.39 3017.5 2580.4 TRUE FALSE FALSE 2535.097145 2717.392583 3215.096139 2564.743677 2535.204511 2710.415672 2744.810208 2449.797569 2686.487799 2670.068708 0.949450154 1.017723842 1.204124871 0.960553438 0.949490365 1.015110834 1.027992351 0.917503569 1.006149314 1 11.38266115 -2.864734668 14.54112153 0.992853067 0.560483721 0 0.075958756 0 0 0.010027899 0 0.001365417 2.864734668 -0.432369345 AREETDK(ac)EEPASK ddPTM_HeLa_Curcumin_4h_R1 2 AREETDKEEPASK 13 2 P05455 P05455 SSB Lupus La protein 0 1 ; AREETDK(1)EEPASK;AREETDK(1)EEPASK 126.56 0.00031865 2780200 1176.91 2003.83 1027.18 1010.63 1408.86 2023.3 1464.83 1187.48 1619.83 1112.89 FALSE TRUE FALSE 1083.756332 2177.032136 1065.248194 1006.448281 1392.060265 1603.644773 1505.929187 1549.537186 1442.138702 1151.562845 0.941117835 1.890502239 0.925045645 0.873984677 1.208844373 1.392581204 1.307726447 1.345594982 1.252331741 1 10.16937743 -4.446209891 0.191580815 0.908982872 1.727539519 0 0.295543615 19.77528998 0.738429391 0.444664815 3.993854932 3.58E-05 4.446209891 0.818556647 AREETDKEEPASK ddPTM_HeLa_Curcumin_4h_R1 1 AREETDKEEPASK 13 2 P05455 P05455 SSB Lupus La protein 0 0 71.176 0.014138 1525900 1880.6 3013.6 1321.7 1503.8 1438.8 2066.5 1001.8 1057.5 1192.3 1866.9 FALSE FALSE TRUE 1731.748526 3274.082156 1370.683365 1497.577674 1421.64325 1637.884606 1029.907812 1379.926882 1061.507673 1931.774636 0.896454738 1.694857203 0.709546206 0.775234153 0.735926036 0.847865261 0.533140767 0.714331194 0.549498711 1 10.91571108 -6.615140494 21.40540336 1.014881907 0.719757399 0.241169115 0.273491746 6.049624829 1397.856138 0.036377666 0.051445779 2.43E-07 6.615140494 -0.295124509 AREETDKEEPASK(ac)QQK ddPTM_HeLa_Curcumin_4h_R1 1 AREETDKEEPASKQQK 16 3 P05455 P05455 SSB Lupus La protein 0 1 AREETDKEEPASK(1)QQK 118.13 8.39E-05 25624000 6977.1 5651.4 6642.4 5473.5 5963.1 7686.3 6318.8 7368.9 7138.8 5732.1 FALSE TRUE FALSE 6424.855173 6139.881834 6888.573187 5450.852107 5891.993927 6092.074738 6496.088522 9615.643688 6355.6915 5931.290048 1.08321379 1.03516803 1.161395435 0.918999419 0.993374777 1.027107878 1.095223546 1.621172394 1.071552976 1 12.53413021 -4.258332687 3.671408695 1.036367965 1.687206453 0.893753081 0.060116045 0.062197095 1.531140659 0.008399408 0.110570138 5.52E-05 4.258332687 0.650838488 AREIFS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 AREIFSK 7 1 O14924-7;O14924-6;O14924-2;O14924-3;O14924-5;O14924-4;O14924 O14924-7 RGS12 Regulator of G-protein signaling 12 1 0 AREIFS(1)K 89.369 0.011519 1742800 757.32 321.37 612.03 706.19 539.57 1074.7 610.13 475.77 695.36 783.66 TRUE FALSE FALSE 697.3773229 349.1477908 634.7123702 703.2679729 533.1359802 851.7951056 627.2486057 620.8300828 619.0807477 810.8921267 0.860012448 0.430572427 0.782733423 0.867276854 0.657468438 1.050441949 0.773529037 0.765613652 0.763456355 1 9.663366195 -8.013516883 1.68119054 0.961572569 0.771804052 0.026713007 0.162382696 0.347384483 2.005646312 0.033802768 0.029526157 9.69E-09 8.013516883 -0.189768517 ARFEELCSDLFR ddPTM_HeLa_Curcumin_4h_R1 2 ARFEELCSDLFR 12 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066;P48741 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 0 ; ; 127.56 0.0024025 169320000 7307.8 4614 5867.9 4610.7 6616.7 8560.9 5930 6634.4 6390.1 5450.1 FALSE FALSE TRUE 6729.379919 5012.8136 6085.369536 4591.622145 6537.800174 6785.272839 6096.37984 8657.198019 5689.122017 5639.490569 1.193260249 0.888877025 1.079063696 0.814190943 1.15928914 1.203171236 1.081016054 1.535102845 1.008800697 1 12.46134913 -1.730362864 1.158970775 1.064226951 199.9999989 0.58817622 0.121321628 392.0270917 1.58013033 0.018914248 206077.4367 0.01860532 1.730362864 198.9357719 ARFEELNADLFR ddPTM_HeLa_Curcumin_4h_R1 4 ARFEELNADLFR 12 1 P11142;E9PKE3;E9PNE6;P11142-2;E9PN89;A8K7Q2;P54652 P11142;P54652 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 0 ;;; ;;; 169.09 5.54E-05 558745900 13852.8 9882.6 12507.2 11174.9 13220.9 15197.9 12053.8 11623.3 13057.3 12250.1 FALSE FALSE TRUE 12756.33626 10736.80791 12970.72783 11128.66122 13063.2494 12045.68422 12391.99719 15167.19066 11624.94686 12675.79006 1.006354334 0.847032639 1.023267802 0.877946161 1.030566879 0.950290606 0.977611425 1.196547954 0.917098406 1 13.62978805 -4.2605909 24.48365321 0.982727142 1.196548039 0.536073179 0.062901721 30.55439068 881467.3865 0.007810263 0.063342706 5.49E-05 4.2605909 0.213820897 ARGS(ph)PPTSSNIVQGQIK ddPTM_HeLa_Curcumin_4h_R1 1 ARGSPPTSSNIVQGQIK 17 1 A2RRE0;Q9Y4E6-2;Q9Y4E6 A2RRE0 WDR7 WD repeat-containing protein 7 1 0 ARGS(0.985)PPT(0.011)S(0.004)SNIVQGQIK 119.94 0.00028275 41487000 7335.4 5197.7 6275.6 6231.1 6148.1 7701.7 5453 2486.4 7106.1 7134.6 TRUE FALSE FALSE 6754.79535 5646.966027 6508.179257 6205.317359 6074.787923 6104.280604 5605.996504 3244.491914 6326.578609 7382.526819 0.914970648 0.764909653 0.881565271 0.84054112 0.822860258 0.826855188 0.759360127 0.439482577 0.85696656 1 12.84989898 -3.362235655 0.305114637 0.973865167 1.93E-33 0.636612824 0.084760218 5.002239757 0.221484026 0.031827758 2.013062051 0.000434275 3.362235655 -0.973865167 ARHDS(ph)PDLAPNVTYSLPR ddPTM_HeLa_Curcumin_4h_R1 2 ARHDSPDLAPNVTYSLPR 18 1 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 0 ARHDS(1)PDLAPNVTYSLPR;ARHDS(1)PDLAPNVTYSLPR ; 84.371 0.0021239 63871000 2544.6 2004.15 2214.79 2640.35 2053.63 2507.3 2226.19 1570.33 2884.7 2596.28 TRUE FALSE FALSE 2343.192225 2177.379796 2296.872066 2629.424931 2029.141804 1987.257717 2288.6509 2049.116388 2568.255627 2686.500537 0.872209848 0.810489246 0.854968028 0.978754664 0.755310403 0.739719829 0.851907851 0.762745572 0.955985525 1 11.39151241 -13.52287874 0.093231096 1.609947774 0.678404009 0.523785439 0.061900358 71.28775133 0.501066147 8.52834266 0.671703177 3.00E-14 13.52287874 -0.931543765 ARIT(ph)VASS(ph)SLPPHFSAGK ddPTM_HeLa_Curcumin_4h_R1 1 ARITVASSSLPPHFSAGK 18 1 F5H2J1;Q8WXR4-6;Q8WXR4-3;Q8WXR4-5;Q8WXR4-2;Q8WXR4-4;Q8WXR4;Q8WXR4-7 F5H2J1 MYO3B Myosin-IIIb 2 0 ARIT(0.974)VAS(0.097)S(0.517)S(0.403)LPPHFS(0.009)AGK 57.52 0.0096065 0 3252.2 3129.5 3158.1 3382.2 3116 1773.3 2052.7 1703.9 3659.4 3023.2 TRUE FALSE FALSE 2994.784938 3400.000035 3275.141964 3368.205353 3078.843735 1405.497591 2110.293237 2223.411266 3257.972975 3128.255975 0.957333723 1.086867591 1.046954594 1.076703882 0.984204541 0.449291107 0.674590972 0.710751065 1.041466236 1 11.61114285 -5.281093154 23.29174687 1.000513979 0.617849089 0.857618967 0.077128906 87.67729026 103906.6062 0.011030962 0.024708817 5.23E-06 5.281093154 -0.38266489 ARNQHLVS(ph)QQK ddPTM_HeLa_Curcumin_4h_R1 1 ARNQHLVSQQK 11 1 P12270 P12270 TPR Nucleoprotein TPR 1 0 ARNQHLVS(1)QQK 67.704 0.018774 18660000 2315.2 1434.9 1740.9 1768.7 1975.6 2221 1837.2 1445 1669.4 1880.6 TRUE FALSE FALSE 2131.949477 1558.926362 1805.419285 1761.381588 1952.04226 1760.339564 1888.746887 1885.573848 1486.270997 1945.95071 1.095582466 0.801112975 0.927782639 0.905152211 1.003130372 0.904616728 0.970603663 0.968973077 0.763776281 1 10.92625945 -7.289455631 24.99945211 1.045136165 0.929053845 0 0.104924598 478.5272088 426997.9672 0.010286837 0.011764694 5.14E-08 7.289455631 -0.11608232 ARPAEVGGMQLR ddPTM_HeLa_Curcumin_4h_R1 2 ARPAEVGGMQLR 12 1 P33316;H0YKC5;H0YKI0;H0YNW5;H0YMM5;P33316-2;H0YNJ9 P33316;H0YNW5;P33316-2 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 0 0 ; ; 101.56 0.0037541 5971400 2191.8 1627.74 1976.76 1767.44 1860.61 2707 2006.4 2019.38 1755.36 1835.09 FALSE FALSE TRUE 2018.316717 1768.434593 2050.020465 1760.126802 1838.423441 2145.537686 2062.694184 2635.079666 1562.8014 1898.859241 1.062910127 0.931314209 1.079606334 0.926939061 0.968172575 1.129908758 1.08628072 1.387717219 0.823021194 1 10.89091725 -3.498060589 1.114475373 1.017409638 2.728784832 0.661803554 0.084606325 2.549373621 0.736911991 0.00857887 7.748757032 0.000317643 3.498060589 1.711375194 ARPATDS(ph)FDDYPPR ddPTM_HeLa_Curcumin_4h_R1 3 ARPATDSFDDYPPR 14 1 E7EX17;P23588-2;P23588;F8VP89;F8W0K0;F8VSC7 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 ARPAT(0.207)DS(0.793)FDDYPPR;ARPAT(0.319)DS(0.681)FDDYPPR;ARPAT(0.013)DS(0.986)FDDY(0.001)PPR ;; 127.07 0.00093282 72781400 6318.84 4877.78 5224.86 5763.61 5876.06 9945.2 10577.6 6581 6066.91 5146.66 TRUE FALSE FALSE 5818.697146 5299.393568 5418.497908 5739.761709 5805.991822 7882.453414 10874.37899 8587.516605 5401.385152 5325.506052 1.092609245 0.995096713 1.0174616 1.077787097 1.090223495 1.48013228 2.041942847 1.612525931 1.014248242 1 12.37870291 -5.093181033 2.835497625 1.04264943 1.826463418 0.898695561 0.106899594 0.049452004 0.76502239 0.013640769 0.042388712 8.07E-06 5.093181033 0.783813988 ARPFPDGLAEDIDKGEVSAR ddPTM_HeLa_Curcumin_4h_R1 4 ARPFPDGLAEDIDKGEVSAR 20 2 P13639 P13639 EEF2 Elongation factor 2 0 0 ;;; ;;; 160.43 3.67E-06 79217000 9008.9 11141.2 7892.6 8764.1 7771.6 9892.2 7754.3 8059.8 9910.5 9030.1 FALSE FALSE TRUE 8295.836059 12104.19568 8185.106699 8727.836476 7678.928746 7840.446212 7971.864788 10517.19592 8823.342945 9343.895303 0.887834869 1.295412169 0.875984419 0.934068308 0.82181237 0.839098252 0.853162897 1.125568682 0.944289577 1 13.18980839 ARQEELYSELQAR ddPTM_HeLa_Curcumin_4h_R1 1 ARQEELYSELQAR 13 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 136.01 0.0010778 18169000 1545.6 1192.7 1211.3 1476 1385 1566 1019.3 1112 1254 1227.3 FALSE FALSE TRUE 1423.264129 1295.791673 1256.191844 1469.892703 1368.48478 1241.193948 1047.898815 1451.043681 1116.439337 1269.948584 1.12072579 1.020349713 0.989167483 1.157442689 1.077590697 0.977357638 0.825150583 1.142600338 0.879121684 1 10.31055437 -5.21144438 6.691524364 1.059092571 0.965195303 0.009958548 0.103574019 0.306991022 33.16678106 0.012076978 0.030929324 6.15E-06 5.21144438 -0.093897267 HLLSPQLVQY(ph)QCGDSGK ddPTM_HeLa_Curcumin_4h_R1 1 HLLSPQLVQYQCGDSGK 17 0 Q9P209 Q9P209 CEP72 Centrosomal protein of 72 kDa 1 0 HLLS(0.191)PQLVQY(0.809)QCGDSGK 150.09 0.0013767 25089000 2714.8 2215.8 2142.1 2366.1 1910.6 1414.6 436.77 133.83 2684.4 2217.6 TRUE FALSE FALSE 2499.920715 2407.323879 2221.48811 2356.309705 1887.817343 1121.196014 449.0245907 174.6341509 2389.928036 2294.661435 1.089450791 1.049097632 0.968111494 1.026865955 0.82269973 0.48861065 0.195682284 0.076104539 1.041516626 1 11.16406559 -5.075325147 1.258697167 1.041535704 0.039750236 0.992085157 0.032135417 0.03910164 0.105085329 0.006208557 0.034237528 8.41E-06 5.075325147 -1.001785468 down ARQPQS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 1 ARQPQSPPR 9 1 O95613-2;O95613 O95613-2 PCNT Pericentrin 1 0 ARQPQS(1)PPR 77.288 0.015735 10498000 692.47 413.31 495.95 412.74 455.06 501.61 211.25 239.38 548.23 450.83 TRUE FALSE FALSE 637.6602688 449.0346747 514.3303433 411.0321912 449.6337067 397.5704317 217.1771064 312.36586 488.0905406 466.4963089 1.366913857 0.962568548 1.102538934 0.881104916 0.963852657 0.852247754 0.465549464 0.669599853 1.046290252 1 8.865721856 -5.324631149 0.742075295 1.161047784 0.508280734 0.648813996 0.136845431 0.48090475 0.394529211 0.029800528 0.194968814 4.74E-06 5.324631149 -0.65276705 KNS(ph)ITEIS(ph)DNEDDLLEYHR ddPTM_HeLa_Curcumin_4h_R1 2 KNSITEISDNEDDLLEYHR 19 1 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 2 0 KNS(0.557)IT(0.45)EIS(0.993)DNEDDLLEYHR;KNS(0.888)IT(0.126)EIS(0.986)DNEDDLLEYHR ; 86.825 0.0011436 10907700 4043.1 3859.1 4124.4 4400.2 4533 3280.9 1818.65 1447.67 3522.7 3749 TRUE FALSE FALSE 3723.084369 4192.663408 4277.253892 4381.993138 4478.946936 2600.404357 1869.676424 1889.057919 3136.268623 3879.277471 0.959736548 1.080784615 1.102590347 1.129590026 1.154582772 0.670332137 0.481965118 0.486961279 0.808467207 1 11.92157226 -5.069596331 3.893046773 1.018462972 0.496224296 0.847940145 0.096289325 0.054647269 1.596317165 0.012216296 0.034844896 8.52E-06 5.069596331 -0.522238677 down S(ph)TSPFGIPEEASEMLEAKPK ddPTM_HeLa_Curcumin_4h_R1 2 STSPFGIPEEASEMLEAKPK 20 1 Q96D09 Q96D09 GPRASP2 G-protein coupled receptor-associated sorting protein 2 1 0 S(0.359)T(0.359)S(0.283)PFGIPEEASEMLEAKPK;S(0.333)T(0.333)S(0.333)PFGIPEEASEMLEAKPK ; 111.77 9.34E-05 113342000 4650.3 4209.74 4647.8 4392.3 3725.24 3553.73 2500.65 1223.08 5038.22 4374.6 TRUE FALSE FALSE 4282.223848 4573.611167 4820.051557 4374.125826 3680.818946 2816.646339 2570.811509 1595.991462 4485.539871 4526.617024 0.946009752 1.010381736 1.064824245 0.966312326 0.813150069 0.622240919 0.567932188 0.3525793 0.990925419 1 12.14421754 -5.066811709 1.108153599 0.986313139 0.375669969 0.955897756 0.047632623 0.101140227 0.198380861 0.008070668 0.051290764 8.57E-06 5.066811709 -0.610643171 down ARS(ph)MDS(ph)SDLSDGAVTLQEYLELKK ddPTM_HeLa_Curcumin_4h_R1 1 ARSMDSSDLSDGAVTLQEYLELKK 24 2 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QLH1 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 2 0 ARS(0.919)MDS(0.392)S(0.324)DLS(0.324)DGAVT(0.041)LQEYLELKK 56.247 0.0060176 0 1011.5 676.4 753.53 621.22 518.68 957.98 607.04 451.67 1055.2 850.02 TRUE FALSE FALSE 931.4387077 734.865002 781.4564847 618.6495562 512.4950798 759.2841493 624.0719086 589.3821038 939.4472 879.5581317 1.058984818 0.835493386 0.888464851 0.703364035 0.582673346 0.863256358 0.709528894 0.670088858 1.068089949 1 9.780635121 -6.78134629 1.404095894 1.027594593 0.710536676 0.755232224 0.079655933 0.135317704 0.537656527 0.01397309 0.020494334 1.65E-07 6.78134629 -0.317057918 ARS(ph)MDSSDLSDGAVTLQEYLELKK ddPTM_HeLa_Curcumin_4h_R1 3 ARSMDSSDLSDGAVTLQEYLELKK 24 2 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QLH1 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 0 ARS(0.583)MDS(0.278)S(0.065)DLS(0.065)DGAVT(0.008)LQEYLELKK;ARS(0.828)MDS(0.145)S(0.027)DLSDGAVTLQEYLELKK;ARS(0.682)MDS(0.125)S(0.189)DLS(0.004)DGAVTLQEYLELKK ;; 105.44 1.26E-06 79948000 7925.4 5471.4 6464.1 6952.2 6621.7 9389.1 7057.2 6264 9425.9 6898.5 TRUE FALSE FALSE 7298.096227 5944.323436 6703.665232 6923.433638 6542.740552 7441.694823 7255.206039 8173.864764 8391.902352 7138.222362 1.022396874 0.832745624 0.9391225 0.969910054 0.916578417 1.04251373 1.016388349 1.145084077 1.175629159 1 12.80134913 -3.996785277 1.383721876 0.984324179 1.305199083 0.242929163 0.084203222 2.042332712 2.140838652 0.009432045 1.084199621 0.000100743 3.996785277 0.320874903 ARS(ph)PGREEVAR ddPTM_HeLa_Curcumin_4h_R1 2 ARSPGREEVAR 11 2 A0A494BZV2;A0A1W2PPU9 A0A494BZV2 1 0 ARS(1)PGREEVAR;ARS(1)PGREEVAR ; 62.732 0.014381 12844400 815.07 625.41 707.81 629.82 571.11 891.71 723.95 451.14 573.58 588.6 TRUE FALSE FALSE 750.5563494 679.4676536 734.0420613 627.2139717 564.2998863 706.7592944 744.2620886 588.6905092 510.659709 609.0538062 1.232331761 1.115611867 1.205217099 1.029817013 0.926518939 1.160421768 1.22199727 0.966565685 0.838447611 1 9.250425877 -6.206023988 24.99466527 1.119547367 1.068050024 0 0.13319458 908.0129601 409551.0471 0.018066614 0.029960075 6.22E-07 6.206023988 -0.051497343 ARS(ph)PSVAAMASPQLCR ddPTM_HeLa_Curcumin_4h_R1 1 ARSPSVAAMASPQLCR 16 1 P25325-2 P25325-2 1 0 ARS(0.992)PS(0.008)VAAMASPQLCR 104.21 0.019735 11506000 1088.9 709.01 632.32 932.25 857.8 891.79 651.72 466.69 1003.1 849.93 TRUE FALSE FALSE 1002.712416 770.2936651 655.7543354 928.3925965 847.5712952 706.8227015 670.0055092 608.9816326 893.0624396 879.4650042 1.140139075 0.875866193 0.745628686 1.055633359 0.963735102 0.803696222 0.761833053 0.692445555 1.015461031 1 9.780482361 -4.299146263 0.37454821 1.060327888 0.410236593 0.472350129 0.103963839 3.470602071 0.341208814 0.036376491 1.009603439 5.02E-05 4.299146263 -0.650091295 ARSDEGQLS(ph)PATR ddPTM_HeLa_Curcumin_4h_R1 1 ARSDEGQLSPATR 13 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 ARSDEGQLS(0.671)PAT(0.329)R 76.341 0.011628 129490000 2751.6 2061.6 2101.3 2322.2 2060.9 2577.1 1889.6 1944.7 2985.1 2432.5 TRUE FALSE FALSE 2533.807957 2239.795518 2179.176026 2312.591352 2036.325114 2042.58041 1942.61709 2537.630078 2657.641998 2517.029194 1.006666098 0.88985679 0.865773044 0.91877812 0.809019267 0.811504457 0.771789654 1.008184603 1.05586459 1 11.29750623 -7.167077734 3.086039848 1.003693823 0.858163938 0.540536414 0.064183827 0.14129994 2.58152977 0.010124007 0.012428775 6.81E-08 7.167077734 -0.145529885 ARSMDS(ph)SDLSDGAVTLQEYLELKK ddPTM_HeLa_Curcumin_4h_R1 1 ARSMDSSDLSDGAVTLQEYLELKK 24 2 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QLH1 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 0 ARS(0.08)MDS(0.307)S(0.307)DLS(0.307)DGAVTLQEYLELKK 83.436 0.00097637 22222000 1537.6 1335 1397.3 1520 1193.4 1930.6 1592.5 1206.8 2093.2 1741.5 TRUE FALSE FALSE 1415.897338 1450.391451 1449.085167 1513.710643 1179.169484 1530.171798 1637.181264 1574.747765 1863.581197 1802.016995 0.785729181 0.804871128 0.804146227 0.840009082 0.654360912 0.849143932 0.908527094 0.87388064 1.034164052 1 10.8153969 -9.263035481 0.887304836 1.005457904 0.812725927 0.595644525 0.065702058 0.400989294 0.541539687 0.052034207 0.012717309 5.46E-10 9.263035481 -0.192731976 ART(ph)PLTAAQQK ddPTM_HeLa_Curcumin_4h_R1 1 ARTPLTAAQQK 11 1 I3L2J0 I3L2J0 CIC 1 0 ART(1)PLTAAQQK 105.99 0.0067074 7876900 3263.8 2323.7 2502.7 2647.8 2990.8 3696.7 2607.8 2286.7 3753.7 3052.5 TRUE FALSE FALSE 3005.466786 2524.550274 2595.452264 2636.844105 2955.136663 2929.96275 2680.967849 2983.904303 3341.928501 3158.574148 0.951526431 0.79926896 0.821716427 0.834821024 0.935591987 0.927621962 0.848790538 0.94469978 1.058049723 1 11.62505772 -7.464244883 5.633443222 0.979155102 0.873044364 0.543777475 0.053746621 0.13578633 8.606005632 0.008861455 0.009951873 3.43E-08 7.464244883 -0.106110738 ART(ph)SSTDEVLSLEEK ddPTM_HeLa_Curcumin_4h_R1 1 ARTSSTDEVLSLEEK 15 1 K7ENH8;A0A0A0MRB7;P15923-2;K7EMM4 K7ENH8 TCF3 Transcription factor E2-alpha 1 0 ART(0.454)S(0.454)S(0.071)T(0.02)DEVLSLEEK 121.77 0.00097428 13686000 4802 2970.8 3458.5 4397.9 3759.1 5619.4 5930.5 5616.6 4935.8 3578.3 TRUE FALSE FALSE 4421.916633 3227.582714 3586.675052 4379.702655 3714.275188 4453.873096 6096.893869 7329.075484 4394.355089 3702.645659 1.194258657 0.871696352 0.968678989 1.182857626 1.00314087 1.202889368 1.646631741 1.979415845 1.186814914 1 11.85434078 -4.624392651 1.955874607 1.067961554 2.006259874 0.900888971 0.101620565 0.094965858 0.607587249 0.015628105 0.123202536 2.37E-05 4.624392651 0.93829832 ART(ph)TAVLVFDERT(ph)ADR ddPTM_HeLa_Curcumin_4h_R1 1 ARTTAVLVFDERTADR 16 2 Q7Z7M1 Q7Z7M1 GPR144 Probable G-protein coupled receptor 144 2 0 ART(0.732)T(0.268)AVLVFDERT(1)ADR 79.514 0.015 31557000 1695.3 1200.9 1667.2 1573.7 1569.9 1632.9 1286.4 1233.1 2059.1 1657.2 TRUE FALSE FALSE 1561.115216 1304.700445 1728.987899 1567.188446 1551.179968 1294.218133 1322.492922 1609.066514 1833.221882 1714.787577 0.910384025 0.760852518 1.008281097 0.913925706 0.90459016 0.754739626 0.771228425 0.938347429 1.069066458 1 10.74381415 -10.47434528 0.129546235 1.219269438 0.779733066 0.384707273 0.08191228 28.75886895 0.629192495 2.308257623 0.417315291 3.35E-11 10.47434528 -0.439536373 ARTDEVPAGGSRS(ph)EAEDEDDEDYVPYVPLR ddPTM_HeLa_Curcumin_4h_R1 1 ARTDEVPAGGSRSEAEDEDDEDYVPYVPLR 30 2 D6RD33;D6RGI7;A0A499FJW5;Q9UJV9 D6RD33 DDX41 Probable ATP-dependent RNA helicase DDX41 1 0 ARTDEVPAGGS(0.172)RS(0.828)EAEDEDDEDYVPYVPLR 92.412 7.01E-08 19045000 504.46 213.96 318.02 295.51 350.5 428.16 345.2 294.19 452.9 358.16 TRUE FALSE FALSE 464.5314587 232.453749 329.806101 294.2872579 346.3205164 339.3547896 354.8853829 383.8871767 403.2180031 370.6060333 1.253437389 0.627226025 0.889910232 0.794070337 0.9344708 0.915675297 0.957581235 1.035836285 1.087996327 1 8.533742558 -7.281229404 24.99826248 1.119678763 0.882923768 0.453078001 0.117995354 600.8673173 758998.6845 0.02330349 0.026667409 5.23E-08 7.281229404 -0.236754996 ARVDHGAEIIT(ph)QSPGR ddPTM_HeLa_Curcumin_4h_R1 1 ARVDHGAEIITQSPGR 16 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 ARVDHGAEIIT(0.914)QS(0.086)PGR 127.5 0.00039701 75210000 1497.4 803.8 1013.6 1211.5 1065.2 1487.4 1048 836.7 1734.3 1135.5 TRUE FALSE FALSE 1378.87921 873.2768903 1051.164908 1206.487134 1052.498186 1178.896474 1077.404059 1091.805978 1544.051629 1174.95854 1.17355563 0.7432406 0.894639999 1.026833792 0.895774744 1.003351551 0.91697198 0.929229365 1.314132862 1 10.19839414 -7.282610966 24.97770399 1.081956823 0.921834526 0.473992718 0.109579037 597.1197084 704465.1195 0.016011196 0.018319307 5.22E-08 7.282610966 -0.160122296 ARVDHGAEIITQS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 2 ARVDHGAEIITQSPGR 16 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 ARVDHGAEIIT(0.032)QS(0.968)PGR;ARVDHGAEIIT(0.071)QS(0.929)PGR ; 130.47 0.00020267 51339600 7872.6 6313.4 6609.6 6350.7 6565.4 7326.5 5431.8 3513.9 7958.4 6162.5 TRUE FALSE FALSE 7249.475403 6859.102164 6854.55759 6324.422486 6487.111893 5806.901313 5584.201689 4585.271934 7085.383431 6376.646416 1.136879 1.075659793 1.074947103 0.991810126 1.017323444 0.910651294 0.87572704 0.719072634 1.111145729 1 12.63858217 -4.328208956 0.711728117 1.067031191 0.539529347 0.886992913 0.040394685 0.826331959 0.308112869 0.009297843 0.342518738 4.70E-05 4.328208956 -0.527501843 ARVS(ph)SGYVPPPVATPFSSK ddPTM_HeLa_Curcumin_4h_R1 1 ARVSSGYVPPPVATPFSSK 19 1 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 0 ARVS(0.778)S(0.222)GYVPPPVATPFSSK 167.89 6.93E-05 23073000 1409.1 1278.2 1134.3 1383.3 1210.8 2134.1 1739.6 462.92 1328.4 1149.1 TRUE FALSE FALSE 1297.568248 1388.681912 1176.338156 1377.576271 1196.362001 1691.463604 1788.408494 604.062177 1182.677843 1189.031139 1.091281973 1.167910466 0.989324936 1.15857039 1.006165407 1.422556187 1.504088863 0.508028896 0.994656746 1 10.21557078 ARVSS(ph)GYVPPPVATPFSSK ddPTM_HeLa_Curcumin_4h_R1 1 ARVSSGYVPPPVATPFSSK 19 1 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 0 ARVS(0.138)S(0.75)GY(0.112)VPPPVATPFSSK 95.926 0.00060023 75382000 2160 2410.7 2272.2 2517.3 2077.5 3821.7 3052 989.59 2565.8 1874.2 TRUE FALSE FALSE 1989.033721 2619.070166 2356.409731 2506.88408 2052.727169 3029.036341 3137.630906 1291.311435 2284.338159 1939.32831 1.02563022 1.350503755 1.215064885 1.292655847 1.058473265 1.561899718 1.617895685 0.665854991 1.177901723 1 10.92134134 -7.277274957 20.77471117 1.01210303 1.270501241 0.083087445 0.255720948 102.579374 134573.2488 0.039826231 0.045685589 5.28E-08 7.277274957 0.258398211 AS(ph)AS(ph)LPPS(ph)T(ph)GSPAS(ph)ELVK ddPTM_HeLa_Curcumin_4h_R1 1 ASASLPPSTGSPASELVK 18 0 H0Y4J2 H0Y4J2 MRPL37 5 0 AS(0.997)AS(0.996)LPPS(0.996)T(0.985)GS(0.042)PAS(0.984)ELVK 44.998 0.0093898 0 1150.2 1011.7 1224.2 1227 1077.8 1433.3 1300.3 1182.4 1165.3 987.21 TRUE FALSE FALSE 1059.160456 1099.14684 1269.569929 1221.922999 1064.947939 1136.017423 1336.782918 1542.908317 1037.469505 1021.515474 1.036852092 1.07599627 1.242829855 1.19618648 1.042517677 1.112090274 1.308627184 1.510411106 1.015618003 1 9.996495343 -1 0.389820236 1.024169077 8.038259792 0.744132589 0.07794879 22.94527882 0.274999289 0.021423845 124.0070358 0.1 1 7.014090715 AS(ph)ASPSTSSTSSRPK ddPTM_HeLa_Curcumin_4h_R1 1 ASASPSTSSTSSRPK 15 1 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;F5H858 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 0 AS(0.692)AS(0.305)PS(0.001)T(0.002)SSTSSRPK 86.005 0.0047805 12879000 1858.2 1748.1 1342 1496.7 1635.1 2468.2 1669.6 744.72 2012.6 1349.3 TRUE FALSE FALSE 1711.121509 1899.197975 1391.735701 1490.507052 1615.6025 1956.267498 1716.444483 971.7816997 1791.822815 1396.188075 1.225566627 1.36027374 0.99681105 1.067554636 1.157152485 1.401148981 1.229379131 0.696024925 1.283367798 1 10.44727758 -9.457136576 1.241434709 1.001543295 1.16080918 0 0.208250022 0.921131547 2.577528879 0.121552226 0.031346335 3.49E-10 9.457136576 0.159265885 AS(ph)CS(ph)LPTAVPAGAKILS(ph)LTELSH ddPTM_HeLa_Curcumin_4h_R1 1 ASCSLPTAVPAGAKILSLTELSH 23 1 A0A0U1RRC8 A0A0U1RRC8 3 0 AS(0.872)CS(0.564)LPT(0.564)AVPAGAKILS(0.437)LT(0.362)ELS(0.201)H 50.705 0.01662 20587000 744.69 496.24 711.65 660.49 806.53 1074.7 602.91 782.52 771.62 771.68 TRUE FALSE FALSE 685.7470007 539.1327744 738.024375 657.7570674 796.9126565 851.7951056 619.826032 1021.106746 686.9752165 798.4958226 0.858798483 0.675185466 0.924268298 0.823745158 0.998017315 1.066749608 0.776242047 1.278787837 0.860336644 1 9.64114105 -4.247565421 24.41249439 0.912316038 1.27878818 0.509991501 0.112775713 1194.432378 2101663.656 0.016009554 0.428688713 5.66E-05 4.247565421 0.366472142 AS(ph)DPGLPAEEPK ddPTM_HeLa_Curcumin_4h_R1 4 ASDPGLPAEEPK 12 0 P27708;F8VPD4 P27708 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 0 AS(1)DPGLPAEEPK;AS(1)DPGLPAEEPK;AS(1)DPGLPAEEPK;AS(1)DPGLPAEEPK ;;; 198.37 1.30E-06 245576000 27103.4 24157 29197.5 27691.6 37521.9 23677.1 17180.3 8467.2 21170.7 20296.3 TRUE FALSE FALSE 24958.13729 26245.02344 30279.58503 27577.0195 37074.47585 18766.20256 17662.33298 11048.8103 18848.32718 21001.59491 1.188392472 1.249668111 1.441775501 1.313091678 1.765317158 0.893560829 0.840999603 0.526093868 0.897471228 1 14.35821127 -4.772031784 2.531201545 1.187994173 0.617799725 0.467232467 0.244689442 0.219205325 2.727895417 0.036035508 0.169696594 1.69E-05 4.772031784 -0.570194448 SQTT(ph)SLENGVFPR ddPTM_HeLa_Curcumin_4h_R1 1 SQTTSLENGVFPR 13 0 A0A087WX11;J3KNG8;Q8TF40-3;Q8TF40;Q8TF40-2 A0A087WX11 FNIP1 Folliculin-interacting protein 1 1 0 SQTT(0.929)S(0.07)LENGVFPR 234.04 2.30E-19 5858900 2603.2 2461.1 2197.2 2076.3 2266.5 2007.7 1001.7 811.35 2774.9 2406.6 TRUE FALSE FALSE 2397.153973 2673.826518 2278.630165 2067.708821 2239.473468 1591.280389 1029.805006 1058.72688 2470.500412 2490.229171 0.962623842 1.073727089 0.9150283 0.830328728 0.899304166 0.639009617 0.413538247 0.425152389 0.992077533 1 11.2820628 -5.066194561 1.016596159 0.983801887 0.333305292 0.937068154 0.056973178 0.118373144 0.187073771 0.008815633 0.061314441 8.59E-06 5.066194561 -0.650496595 down AS(ph)EPS(ph)KTPSSVQEKK ddPTM_HeLa_Curcumin_4h_R1 1 ASEPSKTPSSVQEKK 15 2 Q9UPA5 Q9UPA5 BSN Protein bassoon 2 0 AS(1)EPS(0.872)KT(0.115)PS(0.013)SVQEKK 97.129 0.0036436 71865000 2434.3 2493.8 2655.1 2477.3 2783.1 2964.4 2669.6 2654.5 2626.1 2251.3 TRUE FALSE FALSE 2241.622586 2709.35296 2753.500342 2467.049589 2749.91335 2349.550024 2744.501791 3463.84483 2338.0234 2329.532507 0.962262849 1.163045783 1.18199696 1.059032051 1.18045717 1.008592933 1.178134146 1.48692702 1.003644891 1 11.18582475 -1 0.457898946 1.004489714 11.08061179 0.61753718 0.090945128 37.54213739 0.398383291 0.020699755 358.3208146 0.1 1 10.07612208 AS(ph)GEWDSGTENR ddPTM_HeLa_Curcumin_4h_R1 1 ASGEWDSGTENR 12 0 A0A0U1RQE4;A0A0U1RQN2;A0A494C1M0;Q5HYK7-3;Q5HYK7-2;Q5HYK7 A0A0U1RQE4 SH3D19 SH3 domain-containing protein 19 1 0 AS(0.624)GEWDS(0.375)GT(0.001)ENR 109.6 0.0056986 7568900 668.6 657.62 585.36 851.94 864.48 1060.8 680.13 416.33 844 771.1 TRUE FALSE FALSE 615.6796045 714.4617425 607.0539565 848.414898 854.1716406 840.7781223 699.2126173 543.2671005 751.4153116 797.8956676 0.771629211 0.895432538 0.760818715 1.063315584 1.070530491 1.053744439 0.87632086 0.680874859 0.941746324 1 9.640056303 -6.254950727 24.920121 0.880761639 0.957497461 0.077328154 0.126805159 1228.166143 4716850.508 0.02174713 0.035518193 5.56E-07 6.254950727 0.076735822 AS(ph)GQAFELILS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 ASGQAFELILSPR 13 0 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 2 0 AS(1)GQAFELILS(1)PR;AS(1)GQAFELILS(1)PR ; 150.61 0.0012556 34360000 4381.3 4307.9 3898 4134.9 3908.4 6712.3 6318.9 2131.11 4727.3 3497.3 TRUE FALSE FALSE 4034.515482 4680.25568 4042.463309 4117.790879 3861.794883 5320.093317 6496.191328 2780.875629 4208.727017 3618.830915 1.114867087 1.293305985 1.117063329 1.137878773 1.067138801 1.470113814 1.795107724 0.768445858 1.163007368 1 11.82130799 -6.818913012 0.359850835 1.000115773 1.352621276 0.040461179 0.258895349 1.857398801 0.60486671 0.143316157 0.250961494 1.52E-07 6.818913012 0.352505503 AS(ph)GQAFELILSPR ddPTM_HeLa_Curcumin_4h_R1 2 ASGQAFELILSPR 13 0 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 1 0 AS(1)GQAFELILSPR;AS(1)GQAFELILSPR ; 166.62 0.00018265 140466000 2394.9 1907.06 2143.6 2190.7 2259.4 3415.7 2038.19 1188.22 3098.3 2229.1 TRUE FALSE FALSE 2205.341138 2071.897769 2223.043702 2181.635464 2232.458131 2707.245317 2095.376126 1550.502808 2758.424242 2306.561059 0.956116522 0.898262702 0.963791395 0.945839025 0.967872982 1.173715002 0.908441646 0.672214075 1.195903412 1 11.17152777 -4.313825825 3.938095126 0.980688534 0.657674057 0.509087173 0.09704267 0.097375317 2.775476017 0.009351847 0.079546392 4.85E-05 4.313825825 -0.323014477 AS(ph)GVAVSDGVIK ddPTM_HeLa_Curcumin_4h_R1 1 ASGVAVSDGVIK 12 0 P23528;E9PP50;E9PS23 P23528 CFL1 Cofilin-1 1 0 AS(0.684)GVAVS(0.316)DGVIK 135.91 0.00171 112690000 7091.5 4964.1 6390.1 6977.2 6367.1 7759.7 6442.2 3644.8 7180.7 6756.1 TRUE FALSE FALSE 6530.200292 5393.174684 6626.922727 6948.330195 6291.176491 6150.25075 6622.950794 4756.082741 6392.995175 6990.873972 0.934103564 0.771459292 0.947939092 0.993914384 0.899912731 0.879754202 0.947370932 0.680327347 0.914477246 1 12.77125711 -3.741854496 1.597341036 0.946301459 8.17E-16 0.50010705 0.06701107 2.952517379 2.221306171 0.010365022 6.587080027 0.000181195 3.741854496 -0.946301459 DGQS(ph)SPQPSPR ddPTM_HeLa_Curcumin_4h_R1 1 DGQSSPQPSPR 11 0 Q5VZK9;Q5VZK9-2;A0A0U1RQQ1 Q5VZK9 LRRC16A Leucine-rich repeat-containing protein 16A 1 0 DGQS(0.775)S(0.225)PQPSPR 139.77 0.0013987 46538000 4466.9 3595.6 3777.5 4052.8 4002.9 3451.1 2277.1 1410 4792.2 4021.6 TRUE FALSE FALSE 4113.340152 3906.387642 3917.497473 4036.030587 3955.168032 2735.302958 2340.989297 1839.902509 4266.507649 4161.350301 0.988462844 0.938730787 0.941400553 0.969884844 0.950453037 0.657311392 0.562555211 0.442140742 1.025270006 1 12.02283602 -5.060830028 1.580479594 0.986280386 0.464291689 0.97093077 0.034062209 0.044332055 0.202037066 0.004850419 0.022090577 8.69E-06 5.060830028 -0.521988696 down AS(ph)LEDAPVDDLTR ddPTM_HeLa_Curcumin_4h_R1 2 ASLEDAPVDDLTR 13 0 Q7Z2W4-2;Q7Z2W4;C9J6P4;Q7Z2W4-3 Q7Z2W4-2 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 0 AS(1)LEDAPVDDLTR;AS(1)LEDAPVDDLTR ; 307.77 5.27E-88 194401000 7430.8 7137.6 7677.2 7247.3 9811 8872 7533.8 4319.3 6334.1 6254.9 TRUE FALSE FALSE 6842.644339 7754.542339 7961.723786 7217.312593 9694.010233 7031.847192 7745.178152 5636.234686 5639.265077 6472.257309 1.05722687 1.198120218 1.230130912 1.115115214 1.497778869 1.086459771 1.196673399 0.870829823 0.871298035 1 12.66005325 -7.389232202 3.174521569 1.023565023 1.181343113 0.234482797 0.153967233 0.302384495 5.56141566 0.02498571 0.02828596 4.08E-08 7.389232202 0.15777809 AS(ph)LEDAPVDDLTRK ddPTM_HeLa_Curcumin_4h_R1 2 ASLEDAPVDDLTRK 14 1 Q7Z2W4-2;Q7Z2W4;C9J6P4;Q7Z2W4-3 Q7Z2W4-2 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 0 AS(1)LEDAPVDDLTRK;AS(1)LEDAPVDDLTRK ; 214.48 1.44E-13 8410000 3336.5 2945.9 3529.3 3308.6 3857.3 4231.9 3193.2 1878.11 3289.9 2910.2 TRUE FALSE FALSE 3072.412504 3200.530469 3660.098963 3294.90989 3811.304217 3354.156237 3282.792598 2450.737093 2929.006201 3011.329233 1.020284488 1.062829807 1.215442975 1.094171256 1.265655105 1.113845739 1.090147355 0.813838974 0.972662228 1 11.55618473 -7.121718698 3.824631812 1.00960386 1.108379445 0.131700435 0.112052602 0.352162043 9.132534278 0.0184046 0.02281537 7.56E-08 7.121718698 0.098775585 AS(ph)LGS(ph)LEGEAEAEASSPK ddPTM_HeLa_Curcumin_4h_R1 3 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 AS(1)LGS(1)LEGEAEAEASSPK;AS(1)LGS(0.999)LEGEAEAEAS(0.001)SPK;AS(1)LGS(0.974)LEGEAEAEAS(0.021)S(0.005)PK ;; 161.08 7.41E-05 34756100 9611.5 9711.6 10562.5 9191.4 10330 10441.5 10169.7 9506.8 9970.1 8703.9 TRUE FALSE FALSE 8850.739633 10551.02743 10953.95554 9153.368422 10206.8215 8275.8152 10455.03441 12405.37956 8876.404974 9006.359877 0.982721072 1.171508531 1.216246707 1.016322748 1.133290434 0.918885689 1.160850172 1.377402161 0.985570763 1 13.13672841 -4.401028795 3.167332127 1.028460179 1.385311682 0.516677772 0.092467094 0.163688781 2.659219601 0.013689671 0.117100234 3.97E-05 4.401028795 0.356851503 AS(ph)LGTLPLGKPR ddPTM_HeLa_Curcumin_4h_R1 1 ASLGTLPLGKPR 12 1 E7EPJ7;O75962-5;O75962-4;O75962 E7EPJ7 TRIO Triple functional domain protein 1 0 AS(0.997)LGT(0.003)LPLGKPR 103.31 0.0033085 20244000 2023.2 1639.6 1733 2180.2 2052 3876.3 3439.2 1301.6 2424.6 2292 TRUE FALSE FALSE 1863.061585 1781.319718 1797.226505 2171.17891 2027.53124 3072.311685 3535.694696 1698.451848 2158.627446 2371.646829 0.785556079 0.75108979 0.757796853 0.915473115 0.854904371 1.295433893 1.490818385 0.716148723 0.910180816 1 11.21167347 -5.269989784 24.53996944 0.873118485 1.199802141 0.344168177 0.195758013 375.8795829 1078789.057 0.027386294 0.062201044 5.37E-06 5.269989784 0.326683656 AS(ph)LTLEEK ddPTM_HeLa_Curcumin_4h_R1 1 ASLTLEEK 8 0 A0A0U1RQQ9;Q6P3W7 A0A0U1RQQ9 SCYL2 SCY1-like protein 2 1 0 AS(0.995)LT(0.005)LEEK 112.3 0.010625 2459800 1838.2 1786 1739.9 1814.9 1536.1 2399.8 1778.4 1085.7 2169.2 1771.2 TRUE FALSE FALSE 1692.70453 1940.373882 1804.382225 1807.390425 1517.783011 1902.054429 1828.297118 1416.724932 1931.244187 1832.749068 0.923587718 1.058723158 0.984522244 0.986163603 0.828145564 1.037814975 0.997570889 0.773005403 1.053741737 1 10.83979356 AS(ph)PAPGSGHPEGPGAHLDMNSLDR ddPTM_HeLa_Curcumin_4h_R1 6 ASPAPGSGHPEGPGAHLDMNSLDR 24 0 O94826 O94826 TOMM70A Mitochondrial import receptor subunit TOM70 1 0 AS(0.996)PAPGS(0.004)GHPEGPGAHLDMNSLDR;AS(0.984)PAPGS(0.016)GHPEGPGAHLDMNSLDR;AS(0.997)PAPGS(0.003)GHPEGPGAHLDMNSLDR;AS(0.883)PAPGS(0.117)GHPEGPGAHLDMNSLDR;AS(0.962)PAPGS(0.038)GHPEGPGAHLDMNSLDR;AS(0.9)PAPGS(0.1)GHPEGPGAHLDMNSLDR ;;;;; 114.04 3.86E-07 101463000 4977.49 5273.25 4836.62 5396.7 6318.35 5293.56 3089.94 2525.47 7562.71 5514.92 TRUE FALSE FALSE 4583.516414 5729.046233 5015.869392 5374.369885 6243.007803 4195.615985 3176.6354 3295.474177 6733.099634 5706.56306 0.80320087 1.00393988 0.878965034 0.941787522 1.094004874 0.73522643 0.556663506 0.577488436 1.179887011 1 12.47840639 -4.996026756 4.396849014 0.92407676 0.575981424 0.681705243 0.111721733 0.078057405 3.774868416 0.01317647 0.03959974 1.01E-05 4.996026756 -0.348095336 S(ph)QSLPNSLDYTQTSDPGR ddPTM_HeLa_Curcumin_4h_R1 1 SQSLPNSLDYTQTSDPGR 18 0 H0YNE5;H0YLG5;Q96TC7 H0YNE5 RMDN3 Regulator of microtubule dynamics protein 3 1 0 S(0.956)QS(0.044)LPNSLDYTQTSDPGR 348.4 4.57E-174 130420000 1712.9 820.52 1625.1 1464.6 1391.2 972.47 319.04 283.71 1687.9 1144 TRUE FALSE FALSE 1577.322158 891.4420926 1685.327636 1458.539873 1374.610849 770.76876 327.9914037 370.211873 1502.741593 1183.753915 1.332474713 0.753063691 1.423714519 1.232130982 1.161230245 0.651122459 0.277077355 0.312743948 1.269471276 1 10.20915348 -5.060091594 2.577589757 1.157084345 0.292455456 0.801621048 0.177363636 0.09495464 1.228322054 0.026949585 0.089730233 8.71E-06 5.060091594 -0.864628889 down AS(ph)PCSFSER ddPTM_HeLa_Curcumin_4h_R1 1 ASPCSFSER 9 0 A0A1B0GTT1;A0A1B0GVM0;Q9BUH8 A0A1B0GTT1 BEGAIN Brain-enriched guanylate kinase-associated protein 1 0 AS(1)PCSFSER 131.09 0.0037479 28356000 777.55 434.29 488.58 634.61 844.29 500.77 270.63 131.94 854.64 472.4 TRUE FALSE FALSE 716.006097 471.8280924 506.6872046 631.984152 834.2223932 396.9046572 278.2231494 172.1678986 760.8881302 488.8158648 1.464776716 0.965247093 1.036560474 1.292887972 1.706618899 0.811971717 0.569177822 0.35221422 1.556594589 1 8.933147299 -4.950337169 3.546870066 1.225794425 0.465585942 0.649190098 0.24398413 0.116347253 3.014550916 0.035575953 0.117350823 1.12E-05 4.950337169 -0.760208483 AS(ph)PEMSDR ddPTM_HeLa_Curcumin_4h_R1 2 ASPEMSDR 8 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-5;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 0 AS(1)PEMSDR;AS(0.999)PEMS(0.001)DR ; 117.53 0.0090474 20152000 4451.4 3526.8 3945.6 3749.8 3576.4 4796.9 3655.9 2764.2 4264.7 3650.4 TRUE FALSE FALSE 4099.066993 3831.640877 4091.827407 3734.284321 3533.753766 3801.968868 3758.474715 3606.991855 3796.87308 3777.251128 1.08519843 1.014399294 1.083281801 0.988624848 0.935535829 1.006543843 0.99502908 0.954925085 1.00519477 1 11.88312099 -6.087651993 7.257916721 1.04174682 0.975171463 0.468824633 0.032870278 0.200725731 14.53329279 0.005723653 0.009538433 8.17E-07 6.087651993 -0.066575356 AS(ph)PEPEGEAAGK ddPTM_HeLa_Curcumin_4h_R1 2 ASPEPEGEAAGK 12 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 0 AS(1)PEPEGEAAGK;AS(1)PEPEGEAAGK ; 137.62 0.0014893 85908000 4055.5 3465.7 3442.3 3915.3 3537.9 4325.4 2877.9 1966.45 3784.4 3276.6 TRUE FALSE FALSE 3734.502896 3765.259665 3569.874666 3899.099526 3495.712853 3428.263283 2958.646129 2566.011553 3369.260788 3390.461606 1.101473289 1.110544847 1.052917001 1.150020257 1.031043338 1.011149419 0.872638146 0.756832506 0.993746923 1 11.72726599 -4.593563397 1.645517786 1.061224682 0.731624293 0.829117785 0.045968042 0.181424178 0.727861919 0.007488583 0.077421364 2.55E-05 4.593563397 -0.329600389 AS(ph)PEPPDSAEGALK ddPTM_HeLa_Curcumin_4h_R1 2 ASPEPPDSAEGALK 14 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 0 AS(0.999)PEPPDS(0.001)AEGALK;AS(1)PEPPDSAEGALK ; 185.66 4.93E-05 81576000 6388.3 5341.8 6031.2 5852.4 6384.9 7376.4 5869.3 4942.8 5810.9 5242.1 TRUE FALSE FALSE 5882.659314 5803.521389 6254.721578 5828.184319 6308.764238 5846.451491 6033.976762 6449.836966 5173.458808 5424.262585 1.08450858 1.069918961 1.15310081 1.074465741 1.163063944 1.07783342 1.112404989 1.189071669 0.953762604 1 12.4052113 -13.52287874 0.100612442 0.591917225 1.202529934 0.708637784 0.037034076 48.87397064 0.36667428 4.132339951 0.270073739 3.00E-14 13.52287874 0.610612708 AS(ph)PEPPGPESSSR ddPTM_HeLa_Curcumin_4h_R1 2 ASPEPPGPESSSR 13 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 AS(1)PEPPGPESSSR;AS(1)PEPPGPESSSR ; 135.91 0.0012567 273050000 2408.5 2509 2586.2 2303.26 2482.1 2097.04 1757.31 1595.46 2585.3 2089.77 TRUE FALSE FALSE 2217.864684 2725.86678 2682.046847 2293.72972 2452.502579 1662.090265 1806.615389 2081.908409 2301.699058 2162.389352 1.025654645 1.26058093 1.24031634 1.060738538 1.13416327 0.768635983 0.83547183 0.962781475 1.06442397 1 11.0784106 -5.26323346 24.99773344 1.059823398 0.853613968 0.536996224 0.10131338 123.0180066 1714080.135 0.016691147 0.039201362 5.45E-06 5.26323346 -0.20620943 AS(ph)PFEEDQNR ddPTM_HeLa_Curcumin_4h_R1 2 ASPFEEDQNR 10 0 C9JW01;A0A0A0MR59;Q8TB72-2;Q8TB72-4;Q8TB72-3;Q8TB72;A0A0C4DG68 C9JW01 PUM2 Pumilio homolog 2 1 0 AS(1)PFEEDQNR;AS(1)PFEEDQNR ; 140.45 0.0015018 17786600 2437.6 2092.44 2188.56 2821.7 2571.9 2722.4 2472.8 1817.08 2115.43 2369.5 TRUE FALSE FALSE 2244.661388 2273.30119 2269.669959 2810.024553 2541.231772 2157.743552 2542.180113 2371.099327 1883.372622 2451.839949 0.915500781 0.927181724 0.925700701 1.146088086 1.036459078 0.880050736 1.036845865 0.967069375 0.768146641 1 11.25964909 AS(ph)PGGVSTSSSDGK ddPTM_HeLa_Curcumin_4h_R1 2 ASPGGVSTSSSDGK 14 0 P54259 P54259 ATN1 Atrophin-1 1 0 AS(1)PGGVSTSSSDGK;AS(0.999)PGGVSTSSSDGK ; 141.34 0.00010985 9920100 4577.2 4483 4689.9 5094.6 5274.3 5234.1 4535.9 3453.3 4601.5 3959.4 TRUE FALSE FALSE 4214.90979 4870.490544 4863.71182 5073.519895 5211.407417 4148.48866 4663.165146 4506.195273 4096.726962 4096.988855 1.028782342 1.188797606 1.187143044 1.238353355 1.272009176 1.01257016 1.138193271 1.099879798 0.999936077 1 12.00034825 -7.315045848 5.523331402 1.012895845 1.163806078 0.513225961 0.068235095 0.129306456 8.898659581 0.012163446 0.013943423 4.84E-08 7.315045848 0.150910233 AS(ph)PGGVSTSSSDGKAEK ddPTM_HeLa_Curcumin_4h_R1 1 ASPGGVSTSSSDGKAEK 17 1 P54259 P54259 ATN1 Atrophin-1 1 0 AS(1)PGGVSTSSSDGKAEK 249.86 2.73E-39 5269400 1204.1 1005.8 1083.1 1092.4 1100.2 1353.5 1031.2 641.99 1324.2 1051.5 TRUE FALSE FALSE 1108.794214 1092.73687 1123.240639 1087.879938 1087.080834 1072.768843 1060.132697 837.7297956 1178.938573 1088.039547 1.019075288 1.004317236 1.032352769 0.999853306 0.999118862 0.985964937 0.974351254 0.769944253 1.083543862 1 10.08751528 -3.952901102 1.628682788 1.008809952 0.480988078 0.882543293 0.026648825 0.291252142 0.382930679 0.001861487 0.308696633 0.000111455 3.952901102 -0.527821873 GVGDDQLGEES(ph)EERDDHLLPM ddPTM_HeLa_Curcumin_4h_R1 2 GVGDDQLGEESEERDDHLLPM 21 1 H0YF90;F5GX30;P20645 H0YF90 M6PR Cation-dependent mannose-6-phosphate receptor 1 0 GVGDDQLGEES(1)EERDDHLLPM;GVGDDQLGEES(1)EERDDHLLPM ; 84.653 0.00037951 31075000 10826.3 8510.9 9551.2 10850.7 8350.1 7384.9 2543.38 1582.96 11949.6 9881.8 TRUE FALSE FALSE 9969.386931 9246.544272 9905.175874 10805.80268 8250.530511 5853.188495 2614.740398 2065.597217 10638.75878 10225.19181 0.974982877 0.904290544 0.968703185 1.056782393 0.806882713 0.572428234 0.255715535 0.202010608 1.040445888 1 13.31984029 -5.053447268 1.504217481 0.984184513 0.176747007 0.974204041 0.049101843 0.042714224 0.173669194 0.00678198 0.032560262 8.84E-06 5.053447268 -0.807437506 down AS(ph)PLYASYK ddPTM_HeLa_Curcumin_4h_R1 1 ASPLYASYK 9 0 A0A1B0GTT1;A0A1B0GVM0;Q9BUH8 A0A1B0GTT1 BEGAIN Brain-enriched guanylate kinase-associated protein 1 0 AS(0.998)PLYAS(0.002)YK 91.469 0.018132 18235000 2065.2 1174 1593.1 1379.1 1831 1901.8 1186.7 502.11 1598.2 1302 TRUE FALSE FALSE 1901.737241 1275.475329 1652.141687 1373.39365 1809.166521 1507.345242 1219.995608 655.2010276 1422.881458 1347.244403 1.411575536 0.946728987 1.226311784 1.01940943 1.342864381 1.11883578 0.905548841 0.486326776 1.056142045 1 10.39579588 -4.356419841 1.85326881 1.178555659 0.345083516 0.65069178 0.145377704 0.349994276 1.419003979 0.024683966 0.470221472 4.40E-05 4.356419841 -0.833472143 AS(ph)PNLIGATGANSLGK ddPTM_HeLa_Curcumin_4h_R1 2 ASPNLIGATGANSLGK 16 0 Q02078-3;Q02078-5;Q02078;Q02078-8;Q02078-7;Q02078-4;Q02078-6;Q02078-2 Q02078-3;Q02078-8 MEF2A Myocyte-specific enhancer factor 2A 1 0 AS(1)PNLIGATGANSLGK;AS(1)PNLIGATGANSLGK ; 167.97 0.00016348 46481000 3270.6 2174.9 2582.1 2909.9 2553.7 1912.56 1251.22 883.68 2884.6 1735.83 TRUE FALSE FALSE 3011.728559 2362.888665 2677.794897 2897.859605 2523.248795 1515.873497 1286.325866 1153.109964 2568.166597 1796.149963 1.676768989 1.315529724 1.49085263 1.613372861 1.404809647 0.84395709 0.716157276 0.641989805 1.42981747 1 10.81069209 -5.16399635 3.647332281 1.367214838 0.697891904 0.752817616 0.179352606 0.141776301 3.485130719 0.038481782 0.106204894 6.85E-06 5.16399635 -0.669322934 AS(ph)PNSDDTVLSPQELQK ddPTM_HeLa_Curcumin_4h_R1 1 ASPNSDDTVLSPQELQK 17 0 Q9UH62 Q9UH62 ARMCX3 Armadillo repeat-containing X-linked protein 3 1 0 AS(0.996)PNS(0.004)DDTVLSPQELQK 165.74 5.39E-13 0 692.21 716.81 580.34 579.67 464.11 744.96 576.54 435.36 533.95 615.98 TRUE FALSE FALSE 637.4208481 778.7678624 601.8479109 577.2714791 458.5757914 590.4468986 592.7161607 568.0992598 475.3770209 637.3852592 1.000055836 1.221816556 0.944245105 0.905686899 0.719464068 0.926357945 0.929918212 0.891296514 0.745823682 1 9.316021844 -6.391657452 3.850597875 1.018737995 0.872097905 0.150481701 0.122100094 0.190036777 4.961824864 0.013556966 0.021068041 4.06E-07 6.391657452 -0.14664009 AS(ph)PPAESMSVYR ddPTM_HeLa_Curcumin_4h_R1 3 ASPPAESMSVYR 12 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 0 AS(1)PPAESMSVYR;AS(1)PPAESMSVYR;AS(0.994)PPAES(0.006)MSVYR ;; 122.46 0.0033139 147049000 1112.46 977.62 1155.45 1196.5 1293.1 1127.62 986.21 638.63 1317.53 991.97 TRUE FALSE FALSE 1024.407617 1062.121117 1198.271993 1191.5492 1277.680627 893.7389011 1013.880398 833.3453471 1173.000255 1026.440884 0.99801911 1.034761118 1.167404779 1.160855164 1.244767865 0.87071639 0.98776307 0.811878561 1.142784036 1 10.00343482 -4.410700842 1.511786665 1.037825223 0.782626252 0.332648529 0.106547668 0.901898413 2.328574023 0.016076476 0.313380622 3.88E-05 4.410700842 -0.255198971 AS(ph)PPGDLQNPK ddPTM_HeLa_Curcumin_4h_R1 1 ASPPGDLQNPK 11 0 O00273 O00273 DFFA DNA fragmentation factor subunit alpha 1 0 AS(1)PPGDLQNPK 127.56 0.0032103 50034000 2596.3 2543.1 2862.1 2684.6 3363.6 3131.1 2409.8 1822.6 2045 2204.1 TRUE FALSE FALSE 2390.800115 2762.914232 2968.171944 2673.491837 3323.491267 2481.674565 2477.412502 2378.30235 1820.668616 2280.692311 1.048278237 1.211436641 1.301434626 1.172228197 1.457229128 1.088123353 1.086254595 1.042798425 0.798296468 1 11.15525611 -7.331575359 4.092976422 1.020907316 1.199561075 0.38472331 0.133319333 0.195741494 6.298543464 0.020190435 0.023155296 4.66E-08 7.331575359 0.17865376 AS(ph)PPPQGPLPGPPGALHR ddPTM_HeLa_Curcumin_4h_R1 5 ASPPPQGPLPGPPGALHR 18 0 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 0 AS(1)PPPQGPLPGPPGALHR;AS(1)PPPQGPLPGPPGALHR;AS(1)PPPQGPLPGPPGALHR;AS(1)PPPQGPLPGPPGALHR;AS(1)PPPQGPLPGPPGALHR ;;;; 143.14 0.00011512 277351000 6738.13 6309.271 6947.81 7184.75 6282.524 7209 5566.83 3660.824 7824.64 6482.64 TRUE FALSE FALSE 6204.7999 6854.616272 7205.301951 7155.021408 6207.609005 5713.772138 5723.020267 4776.992385 6966.296568 6707.911257 0.924997315 1.021870446 1.074149862 1.066654154 0.925416089 0.851796024 0.853174714 0.71214305 1.038519489 1 12.71164789 -4.779842722 1.219446005 0.982975485 0.718073648 0.743439723 0.055774301 0.33884522 0.724857846 0.009483715 0.089267433 1.66E-05 4.779842722 -0.264901837 AS(ph)PS(ph)PQPSSQPLQIHR ddPTM_HeLa_Curcumin_4h_R1 2 ASPSPQPSSQPLQIHR 16 0 B5MBZ0;Q9HC35 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 2 0 AS(0.999)PS(0.922)PQPS(0.044)S(0.034)QPLQIHR;AS(1)PS(1)PQPSSQPLQIHR ; 148.15 0.00076915 35598400 2523.7 2628.4 2194.7 1833.76 1874.38 1344 943.64 883.59 3252.1 2168.2 TRUE FALSE FALSE 2323.946482 2855.587184 2276.037513 1826.172387 1852.029243 1065.23925 970.1159987 1152.992523 2895.352766 2243.544789 1.035836901 1.272801505 1.014482761 0.813967431 0.825492431 0.474801865 0.432403224 0.513915536 1.290525949 1 11.13156427 -5.555426906 1.354033254 1.037627802 0.447627416 0.826291627 0.123910968 0.112222728 0.399980051 0.015350199 0.046950476 2.78E-06 5.555426906 -0.590000386 AS(ph)PSCSS(ph)PTRDSSGVPVSK ddPTM_HeLa_Curcumin_4h_R1 1 ASPSCSSPTRDSSGVPVSK 19 1 Q8N5I9;J3KN91;A0A087WT30 Q8N5I9 C12orf45 Uncharacterized protein C12orf45 2 0 AS(0.976)PS(0.025)CS(0.151)S(0.661)PT(0.023)RDS(0.142)S(0.016)GVPVS(0.006)K 160.76 7.51E-05 5832300 2622.8 2270.1 2306.1 2705.7 2083.1 3284.9 2756.1 1277.8 2730.2 1839.4 TRUE FALSE FALSE 2415.202612 2466.317329 2391.566095 2694.50453 2058.260393 2603.574712 2833.428748 1667.395338 2430.703891 1903.319013 1.268942619 1.295798188 1.256524039 1.415687287 1.081405891 1.367912942 1.488677793 0.876046173 1.277086959 1 10.89430167 -9.089692202 0.741766442 0.989054569 1.269995465 0 0.184896114 0.736455689 0.697122833 0.122286257 0.031541045 8.13E-10 9.089692202 0.280940896 AS(ph)PSKPASAPASR ddPTM_HeLa_Curcumin_4h_R1 1 ASPSKPASAPASR 13 1 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;P27816-4;B5MEG9;H7C4C5;H0Y2V1;F8W9U4 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 AS(0.973)PS(0.027)KPASAPASR 135.14 0.0125 99256000 2659.7 1887.2 1941.7 1953.2 2402 3000.8 2057.3 1270.8 2471.6 1938.3 TRUE FALSE FALSE 2449.181938 2050.321159 2013.66111 1945.118176 2373.357719 2378.400254 2115.022301 1658.26107 2200.471664 2005.655781 1.221137726 1.022269713 1.003991378 0.969816553 1.183332525 1.185846683 1.054529058 0.826792457 1.097133259 1 10.96985831 VEHS(ph)PGPPLADAECQEGLSENSACR ddPTM_HeLa_Curcumin_4h_R1 2 VEHSPGPPLADAECQEGLSENSACR 25 0 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9 A0A087WUE6 GON4L GON-4-like protein 1 0 VEHS(1)PGPPLADAECQEGLSENSACR;VEHS(1)PGPPLADAECQEGLSENSACR ; 114.8 1.27E-08 16481400 5709.4 5277.4 5055.7 5812.4 5086.4 4946.8 2885.7 1998.69 6080.9 5490.7 TRUE FALSE FALSE 5257.494965 5733.55494 5243.068689 5788.349829 5025.748002 3920.777918 2966.664976 2608.08138 5413.840484 5681.501416 0.925370704 1.009161931 0.922831538 1.018806369 0.884580964 0.690095387 0.522162147 0.459047915 0.952889049 1 12.47205652 -5.050492069 1.614243739 0.968330377 0.460149628 0.971111541 0.033291756 0.050723822 0.242151434 0.005499371 0.024933751 8.90E-06 5.050492069 -0.508180749 down AS(ph)PSTAGETPSGVK ddPTM_HeLa_Curcumin_4h_R1 1 ASPSTAGETPSGVK 14 0 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 0 AS(0.987)PS(0.012)T(0.001)AGETPSGVK 185.95 4.50E-05 12409000 1983.7 1841 1935.7 1857.1 2508.3 2055.9 1795.3 1228.4 1985.1 1389.3 TRUE FALSE FALSE 1826.688052 2000.127837 2007.438745 1849.415812 2478.390161 1629.483165 1845.671286 1602.933505 1767.339496 1437.578072 1.270670503 1.391317714 1.396403287 1.286480261 1.724003871 1.133491946 1.283875514 1.11502362 1.229386794 1 10.48942459 -8.644842002 0.745128013 1.010690105 1.336930357 0.149934154 0.17317086 0.49754414 0.552975151 0.083781542 0.035107612 2.27E-09 8.644842002 0.326240252 AS(ph)PSYSALDK ddPTM_HeLa_Curcumin_4h_R1 1 ASPSYSALDK 10 0 Q9NYD6;D6RAG4 Q9NYD6 HOXC10 Homeobox protein Hox-C10 1 0 AS(0.95)PS(0.008)YS(0.042)ALDK 116.74 0.0052526 0 1863.4 1607.4 1836.1 1589.1 2278.5 2536 1468.2 1102.9 1557.8 1151.3 TRUE FALSE FALSE 1715.909924 1746.336494 1904.147481 1582.524725 2251.330376 2010.005013 1509.393741 1439.169133 1386.913237 1191.307589 1.440358426 1.465898907 1.598367624 1.328393053 1.889797728 1.687225895 1.267005897 1.208058394 1.164194075 1 10.21833024 -8.883694936 0.624391749 0.975479269 1.507478519 0.39181073 0.197713775 0.59977175 0.417031616 0.167121102 0.04736209 1.31E-09 8.883694936 0.53199925 PAT(ph)PGASSVEQLRK ddPTM_HeLa_Curcumin_4h_R1 1 PATPGASSVEQLRK 14 1 Q9H3U1 Q9H3U1 UNC45A Protein unc-45 homolog A 1 0 PAT(0.99)PGAS(0.008)S(0.002)VEQLRK 80.719 0.0096549 44603000 4551.1 3322 4366.8 4602.3 3918.7 2776.8 2076 682.8 3169.7 3505.7 TRUE FALSE FALSE 4190.875633 3609.138877 4528.637449 4583.256902 3871.972062 2200.860379 2134.246973 890.9825768 2821.99184 3627.522814 1.155299594 0.994932096 1.248410467 1.263467423 1.067387377 0.606711657 0.588348325 0.24561736 0.777939102 1 11.82476897 -5.047718749 1.86984426 1.098991591 0.376569375 0.766125894 0.1522933 0.100030217 0.660903774 0.017999659 0.073063861 8.96E-06 5.047718749 -0.722422217 down AS(ph)PTLDFTER ddPTM_HeLa_Curcumin_4h_R1 2 ASPTLDFTER 10 0 J3KQV8;O43426;A0A0D9SGJ6 J3KQV8 SYNJ1 Synaptojanin-1 1 0 AS(0.852)PT(0.148)LDFTER;AS(0.951)PT(0.049)LDFTER ; 131.09 0.002766 46216000 3017.3 3036.7 2442 2960.2 3101.4 3433.4 2695.6 2907.6 3217.6 2645.3 TRUE FALSE FALSE 2778.477521 3299.178817 2532.502668 2947.951477 3064.417831 2721.274138 2771.231281 3794.113855 2864.63733 2737.223978 1.015071307 1.205301007 0.925208419 1.076985844 1.119534921 0.994172987 1.012424012 1.386117426 1.046548384 1 11.41849778 -4.260038799 24.38685567 1.026556134 1.386117594 0.647516841 0.07476263 36.67436218 638475.2626 0.009776773 0.081917906 5.49E-05 4.260038799 0.35956146 AS(ph)PTSTEEEQVMLR ddPTM_HeLa_Curcumin_4h_R1 2 ASPTSTEEEQVMLR 14 0 Q96PE3-2;Q96PE3-4;Q96PE3-3;Q96PE3 Q96PE3-2 INPP4A "Type I inositol 3,4-bisphosphate 4-phosphatase" 1 0 AS(0.625)PT(0.116)S(0.074)T(0.185)EEEQVMLR;AS(0.995)PT(0.003)S(0.002)T(0.001)EEEQVMLR ; 159.41 0.0003127 12888500 2752.1 2121.41 2714.4 2442.9 3212.5 2520.7 2313.65 2324.08 2446.34 2369.02 TRUE FALSE FALSE 2534.268381 2304.775228 2814.998052 2432.791927 3174.193036 1997.878406 2378.564792 3032.681293 2177.982622 2451.343269 1.033828437 0.940209091 1.148349188 0.992432173 1.294879047 0.815013724 0.970310777 1.237150803 0.888485366 1 11.25935681 -6.769168245 24.99896066 1.010738488 1.065774677 0.099470401 0.136608702 501.3433867 1621591.965 0.019884216 0.026400824 1.70E-07 6.769168245 0.055036189 AS(ph)PVPAPSSGLHAAVR ddPTM_HeLa_Curcumin_4h_R1 2 ASPVPAPSSGLHAAVR 16 0 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 1 0 AS(0.997)PVPAPS(0.001)S(0.002)GLHAAVR;AS(0.999)PVPAPS(0.001)S(0.001)GLHAAVR ; 123.63 0.00071458 13459000 1035.85 1117.66 1127.88 994.15 1296.25 1260.59 792.39 641.57 1271.4 1075.61 TRUE FALSE FALSE 953.8613795 1214.26555 1169.680225 990.0364707 1280.793065 999.1294242 814.6223308 837.1817396 1131.930601 1112.987367 0.857028038 1.090996705 1.050937557 0.889530735 1.150770532 0.897700597 0.731924148 0.752193389 1.017020169 1 10.1202215 -4.861743729 4.411321712 0.963505886 0.742168094 0.546987951 0.089975514 0.139451899 4.724364009 0.01367808 0.044889031 1.37E-05 4.861743729 -0.221337792 AS(ph)QEANLLTLAQK ddPTM_HeLa_Curcumin_4h_R1 1 ASQEANLLTLAQK 13 0 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2;H7C1L3 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 0 AS(1)QEANLLTLAQK 169.37 1.11E-09 0 635 392.97 472.81 573.45 544.8 635.86 437.08 409.14 595.5 467.82 TRUE FALSE FALSE 584.73908 426.9365758 490.3327545 571.0772158 538.3036158 503.9754684 449.3432885 533.8849026 530.1751399 484.0767102 1.207947145 0.881960579 1.012923663 1.179724626 1.112021307 1.041106622 0.928248104 1.102893181 1.095229596 1 8.919091875 -5.004446308 24.60675085 1.083901409 1.007847334 0.034807451 0.096806831 331.2446581 1833229.498 0.015446186 0.044749906 9.90E-06 5.004446308 -0.076054075 AS(ph)QGISNYLAWY(ph)QQKPGK ddPTM_HeLa_Curcumin_4h_R1 1 ASQGISNYLAWYQQKPGK 18 1 A0A075B6S5 A0A075B6S5 IGKV1-27 2 0 AS(0.808)QGIS(0.07)NY(0.141)LAWY(0.981)QQKPGK 45.084 0.020224 137710000 3218.4 4339.7 3303.4 3005.7 2954.1 3057.1 4164.4 2650.2 4505 5826.8 TRUE FALSE FALSE 2963.660244 4714.804331 3425.82691 2993.26321 2918.874287 2423.022999 4281.241856 3458.23378 4010.812771 6029.280866 0.491544566 0.781984524 0.568198262 0.496454432 0.484116489 0.401875954 0.710075041 0.573573177 0.665222414 1 12.55777022 -9.447807524 0.668536648 1.077582608 0.553398744 0.227002398 0.148001597 0.49393223 0.298887153 0.158449152 0.022831657 3.57E-10 9.447807524 -0.524183864 AS(ph)S(ph)HSSQTQGGGSVTK ddPTM_HeLa_Curcumin_4h_R1 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 AS(0.945)S(0.711)HS(0.192)S(0.152)QT(0.001)QGGGSVTK 102.64 0.0047706 20563000 5011.8 3945.1 3984.1 4367 6856.4 8753.5 5522.2 2361.6 6139.5 4296.7 TRUE FALSE FALSE 4615.110742 4286.096865 4131.754251 4348.930511 6774.641908 6937.925428 5677.13807 3081.640969 5466.01221 4446.010005 1.038034268 0.964032213 0.929317353 0.978164805 1.523757684 1.560483539 1.276906274 0.693125064 1.229419683 1 12.11829548 -5.795497319 24.99882315 1.004010542 1.285729269 0.198507454 0.233073696 181.0299976 132877.1084 0.032424269 0.058776213 1.60E-06 5.795497319 0.281718727 AS(ph)S(ph)TQAT(ph)KT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 ASSTQATKTK 10 1 O43172 O43172 PRPF4 U4/U6 small nuclear ribonucleoprotein Prp4 4 0 AS(0.98)S(0.576)T(0.444)QAT(1)KT(1)K 74.611 0.0061767 0 398.76 619.32 396.95 387.8 273 302.25 385.33 157.16 451.75 600.51 TRUE FALSE FALSE 367.1977252 672.8512612 411.6613162 386.1953864 269.7446533 239.5599429 396.1413227 205.0773605 402.1941552 621.3776778 0.590941288 1.082837838 0.662497754 0.621514741 0.434107408 0.385530333 0.637521007 0.330036575 0.647261995 1 9.279326605 -6.184738576 2.009811941 0.821876464 0.4588467 0.519665776 0.159891062 0.229928432 1.813730262 0.0291059 0.052548588 6.54E-07 6.184738576 -0.363029764 AS(ph)SCETYEYPQR ddPTM_HeLa_Curcumin_4h_R1 1 ASSCETYEYPQR 12 0 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 0 AS(0.651)S(0.349)CETYEYPQR 193.49 3.97E-06 18620000 1549.1 1049 1159.3 1400.3 1553.4 1916.3 2079.3 1692.1 1267.2 1370.1 TRUE FALSE FALSE 1426.4871 1139.670886 1202.264678 1394.50593 1534.87672 1518.837779 2137.639562 2208.013501 1128.19133 1417.710873 1.006190421 0.803881036 0.848032346 0.983632105 1.082644387 1.071331121 1.507810656 1.557449789 0.795783789 1 10.46934763 -4.787889321 2.43740677 0.979137785 1.575589013 0.85077089 0.09780188 0.074117977 0.852679101 0.012403264 0.058622038 1.63E-05 4.787889321 0.596451228 AS(ph)SHS(ph)SQTQGGGSVTK ddPTM_HeLa_Curcumin_4h_R1 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 AS(0.743)S(0.237)HS(0.59)S(0.423)QT(0.008)QGGGSVTK 119.04 0.00062312 0 3897.8 3159.1 2322 2480.4 3973.2 6224.7 3670.2 1363.9 4097.8 2972.8 TRUE FALSE FALSE 3589.285017 3432.158527 2408.055363 2470.136762 3925.822185 4933.627053 3773.175934 1779.746831 3648.281592 3076.104579 1.166828021 1.115748324 0.782826234 0.803008057 1.276231703 1.603855437 1.226608471 0.578571627 1.186007009 1 11.58688884 -9.67159646 1.54066995 1.000183254 1.095730614 0 0.282370392 2.095386825 8.983147854 0.201384299 0.045438056 2.13E-10 9.67159646 0.09554736 AS(ph)SHSS(ph)QTQGGGSVTK ddPTM_HeLa_Curcumin_4h_R1 3 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 AS(0.811)S(0.196)HS(0.081)S(0.912)QTQGGGSVTK;AS(0.83)S(0.157)HS(0.362)S(0.65)QT(0.001)QGGGSVTK;AS(0.953)S(0.07)HS(0.031)S(0.947)QTQGGGSVTK ;; 114.56 0.0027519 1869092000 25620.5 21306.8 19274.6 18587.9 31945 44509 27719.9 11087.7 29721.4 21653 TRUE FALSE FALSE 23592.61039 23148.46485 19988.93363 18510.98819 31564.07674 35277.33168 28497.64579 14468.28869 26461.03678 22405.44014 1.052985804 1.033162692 0.892146439 0.826182752 1.408768431 1.574498491 1.27190743 0.645748916 1.181009461 1 14.45156145 -5.758474523 24.99824239 1.002781862 1.253512535 0.173746604 0.239894818 94.5769996 797413.0104 0.03370065 0.065134633 1.74E-06 5.758474523 0.250730674 AS(ph)SHSSQTQGGGSVTK ddPTM_HeLa_Curcumin_4h_R1 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 AS(0.477)S(0.477)HS(0.041)S(0.005)QT(0.001)QGGGSVTK 97.836 0.0016398 16085000 4932.2 5298.2 3870.2 3267.7 6598.5 13585 4537.3 2868.7 6227.7 4363 TRUE FALSE FALSE 4541.811166 5756.1528 4013.633017 3254.179123 6519.817197 10767.31787 4664.604426 3743.353424 5544.536891 4514.613925 1.006024267 1.27500444 0.889031284 0.720810058 1.444158306 2.384991949 1.033223328 0.829163575 1.228130906 1 12.1403869 -5.698341814 10.67724672 0.998549669 1.464716081 0.186755635 0.406904181 0.554626208 90.93956117 0.057427685 0.114863965 2.00E-06 5.698341814 0.466166413 MSLFMYRT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 MSLFMYRTR 9 1 F1T0K3;P16499 F1T0K3 PDE6A "Rod cGMP-specific 3,5-cyclic phosphodiesterase subunit alpha" 1 0 MSLFMY(0.066)RT(0.934)R 51.059 0.020257 7717800 1245.3 1371.3 989.56 1016.6 745.63 1627.3 1662 1823.9 1067.8 1100.1 TRUE FALSE FALSE 1146.733191 1489.829062 1026.233964 1012.393579 736.7388492 1289.779637 1708.631247 2379.998714 950.6650115 1138.328393 1.007383456 1.3087867 0.901527161 0.889368643 0.647211168 1.133047058 1.501000289 2.090783932 0.835141263 1 10.1527011 -4.467256286 1.983912775 0.988146956 2.185255742 0.825993787 0.164480653 0.146382536 0.827974732 0.022796422 0.27172454 3.41E-05 4.467256286 1.197108786 up AS(ph)SMPATLLHSR ddPTM_HeLa_Curcumin_4h_R1 1 ASSMPATLLHSR 12 0 Q5T7N3 Q5T7N3 KANK4 KN motif and ankyrin repeat domain-containing protein 4 1 0 AS(0.5)S(0.5)MPATLLHSR 127.78 0.0016717 9799900 3164.3 1890.4 2772.4 2873.9 2930.7 3881.2 3328.4 2893.8 2690.1 2739.4 TRUE FALSE FALSE 2913.842316 2053.797753 2875.147583 2862.008563 2895.753317 3076.19537 3421.785946 3776.106299 2395.00276 2834.593946 1.027957574 0.724547428 1.014306683 1.009671444 1.021576061 1.085233169 1.207152069 1.332150696 0.844919169 1 11.46892637 -4.567403364 1.149865949 0.98914952 1.403102465 0.633193297 0.096678568 0.495012691 0.75380795 0.013273297 0.214754441 2.71E-05 4.567403364 0.413952945 AS(ph)SPAQCVT(ph)PVQTVV ddPTM_HeLa_Curcumin_4h_R1 1 ASSPAQCVTPVQTVV 15 0 Q13614;Q13614-2 Q13614 MTMR2 Myotubularin-related protein 2 2 0 AS(0.498)S(0.502)PAQCVT(0.98)PVQT(0.02)VV 111.58 0.0092907 8486200 1509.7 1261.3 1250 1362.8 1201.5 1704.7 1337.2 887.13 1822.8 1233 TRUE FALSE FALSE 1390.205652 1370.321152 1296.3261 1357.161095 1187.172897 1351.126004 1374.718233 1157.611853 1622.8434 1275.846658 1.089633807 1.07404847 1.016051648 1.063733707 0.930498105 1.059003443 1.077494873 0.907328358 1.271973705 1 10.31723923 AS(ph)SPHGLGSPLVAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 ASSPHGLGSPLVASPR 16 0 Q8IZW8 Q8IZW8 TNS4 Tensin-4 2 0 AS(0.773)S(0.142)PHGLGS(0.097)PLVAS(0.988)PR 100.69 0.0016672 0 1566.8 1219.7 1294.3 1323.6 2120.4 2014.8 743.37 478.27 2201.5 751.02 TRUE FALSE FALSE 1442.786127 1325.125433 1342.267897 1318.123294 2095.115615 1596.907769 764.2269615 624.0923213 1960.000958 777.1178891 1.856585914 1.705179422 1.727238448 1.696169027 2.696007445 2.054910575 0.983411876 0.803085774 2.522141087 1 9.601989662 -9.300455118 0.937486817 0.983383179 1.722106508 0 0.685050034 0.779482956 1.183917547 0.402011662 0.098494905 5.01E-10 9.300455118 0.738723329 AS(ph)SPHGLGSPLVASPR ddPTM_HeLa_Curcumin_4h_R1 1 ASSPHGLGSPLVASPR 16 0 Q8IZW8 Q8IZW8 TNS4 Tensin-4 1 0 AS(0.807)S(0.152)PHGLGS(0.019)PLVAS(0.022)PR 72.815 0.010069 8607100 4419.9 3708.2 3692.1 3544.7 5038.5 5713.7 2954.8 2197 5148.4 3318 TRUE FALSE FALSE 4070.060251 4028.720285 3828.932474 3530.032971 4978.419178 4528.614213 3037.703736 2866.855186 4583.633401 3433.300253 1.185465864 1.173424981 1.115233796 1.028174849 1.450038975 1.319026557 0.884776603 0.83501441 1.335051718 1 11.74538032 -4.630296139 7.92398397 1.131307964 0.847955115 0.412123158 0.145423095 0.180532401 11.81449904 0.020509185 0.077455386 2.34E-05 4.630296139 -0.283352849 AS(ph)SPIKQSHEPVPDTSVEK ddPTM_HeLa_Curcumin_4h_R1 1 ASSPIKQSHEPVPDTSVEK 19 1 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 0 AS(0.439)S(0.439)PIKQS(0.122)HEPVPDTSVEK 48.555 0.018209 67588000 5208 4419.3 4708 4642.8 4179.3 5556.2 3830.7 2054.2 5748.5 4851.8 TRUE FALSE FALSE 4795.781305 4801.2846 4882.482622 4623.589324 4129.464577 4403.781489 3938.179132 2680.516124 5117.903932 5020.399689 0.955258864 0.956355051 0.972528668 0.920960404 0.822537016 0.877177468 0.784435379 0.533924845 1.01942161 1 12.29358651 -3.697643527 0.572935907 0.977565334 2.86E-21 0.912840032 0.040436714 1.205645567 0.170678597 0.007202966 0.904776006 0.000200612 3.697643527 -0.977565334 AS(ph)SPPDRIDIFGR ddPTM_HeLa_Curcumin_4h_R1 2 ASSPPDRIDIFGR 13 1 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 1 0 AS(0.5)S(0.5)PPDRIDIFGR;AS(0.5)S(0.5)PPDRIDIFGR ; 76.311 0.0094288 282390000 4187.65 3774.18 3033.14 3670.28 3720.44 4908.5 3703.42 3844.47 4991.35 4450.11 TRUE FALSE FALSE 3856.193084 4100.403302 3145.550837 3655.093354 3676.076183 3890.42177 3807.327998 5016.631205 4443.811393 4604.750991 0.837437918 0.890472321 0.683109867 0.793765691 0.79832247 0.84487126 0.826826034 1.089446794 0.965049229 1 12.16890743 -9.048496667 0.791902481 1.002078844 0.837330988 0.234584827 0.09736653 0.683349096 0.766894105 0.06737095 0.019407392 8.94E-10 9.048496667 -0.164747856 AS(ph)SPSASSSSSFR ddPTM_HeLa_Curcumin_4h_R1 1 ASSPSASSSSSFR 13 0 A0A0J9YYE2;Q8IXZ2 A0A0J9YYE2 ZC3H3 Zinc finger CCCH domain-containing protein 3 1 0 AS(0.498)S(0.498)PS(0.001)AS(0.001)S(0.001)SSSFR 97.957 0.0080893 22021000 4828.6 4511.8 4682.8 4589.9 4568.1 5778.6 4982.9 5682.1 5460.1 4554.2 TRUE FALSE FALSE 4446.411215 4901.779888 4856.348687 4570.90821 4513.628391 4580.053222 5122.706763 7414.546133 4861.14069 4712.458111 0.943543923 1.040174739 1.030534081 0.969962619 0.957807642 0.971903222 1.087056191 1.573392475 1.03155096 1 12.20226408 -4.251091762 2.677178507 0.980415859 1.699915004 0.963326424 0.033709182 0.0612757 0.562054957 0.004857349 0.098784125 5.61E-05 4.251091762 0.719499145 AS(ph)SVNEMR ddPTM_HeLa_Curcumin_4h_R1 1 ASSVNEMR 8 0 P0CG00 P0CG00 ZSCAN5D Putative zinc finger and SCAN domain-containing protein 5D 1 0 AS(0.985)S(0.015)VNEMR 81.525 0.018389 4138500 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 AS(ph)TGPPLIK ddPTM_HeLa_Curcumin_4h_R1 2 ASTGPPLIK 9 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 0 AS(0.942)T(0.058)GPPLIK;AS(0.668)T(0.332)GPPLIK ; 108.43 0.0096566 22195000 4160.5 3921.7 3803 4094 4105.6 5975.4 5137.3 1540.07 4093.3 3910 TRUE FALSE FALSE 3831.192035 4260.674273 3943.942525 4077.060113 4056.643401 4736.034683 5281.438812 2009.630253 3644.275231 4045.872209 0.946938469 1.053091658 0.9748065 1.007708574 1.002662267 1.170584348 1.305389429 0.496711253 0.900739085 1 11.98223504 -7.26647125 23.95470109 0.974943169 1.019000506 0.004208082 0.197030571 1240.646301 5906200.46 0.03067261 0.035662423 5.41E-08 7.26647125 0.044057337 AS(ph)TPDWVSEGPQPGLR ddPTM_HeLa_Curcumin_4h_R1 1 ASTPDWVSEGPQPGLR 16 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 AS(0.586)T(0.414)PDWVSEGPQPGLR 118.08 0.0010578 17885000 2017.9 2003.5 2294.9 1795.2 1684.6 1652.7 3087.1 1446.6 2366.3 2534.6 TRUE FALSE FALSE 1858.181086 2176.673613 2379.951013 1787.771938 1664.512245 1309.91139 3173.715717 1887.661681 2106.72281 2622.677161 0.708505459 0.829943405 0.907451 0.68165917 0.634661509 0.499455827 1.21010537 0.719746108 0.803271879 1 11.35682451 -9.402995448 0.993578737 1.007555236 0.772178237 0.02712537 0.188986419 0.815343511 1.363784183 0.142984294 0.031984583 3.95E-10 9.402995448 -0.235376999 AS(ph)VSPMDEPVPDSES(ph)PIEK ddPTM_HeLa_Curcumin_4h_R1 2 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 AS(0.5)VS(0.5)PMDEPVPDS(0.287)ES(0.713)PIEK;AS(0.5)VS(0.5)PMDEPVPDS(0.301)ES(0.699)PIEK ; 118.85 0.00023594 20162400 6946.5 5835.8 6055.9 6209.7 6461.9 6494.5 6092.4 7191.3 6710.4 5909.2 TRUE FALSE FALSE 6396.677195 6340.220548 6280.336981 6184.005907 6384.846063 5147.467492 6263.336347 9383.894265 5974.285909 6114.54426 1.046141286 1.036908113 1.027114485 1.011360069 1.044206369 0.841839927 1.024334125 1.534684167 0.97706152 1 12.57802926 -4.262470393 6.904268604 1.012201074 1.542705753 0.884226365 0.057820794 0.0252469 8.787359107 0.007785652 0.062717482 5.46E-05 4.262470393 0.530504678 AS(ph)VSPMDEPVPDSESPIEK ddPTM_HeLa_Curcumin_4h_R1 2 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 AS(0.61)VS(0.39)PMDEPVPDSESPIEK;AS(0.572)VS(0.428)PMDEPVPDSESPIEK ; 104.23 0.00042944 25640200 7209.8 6347.5 6685.4 6990 6503.5 7261.5 6194.2 7156.3 7957.1 7441.6 TRUE FALSE FALSE 6639.136722 6896.149616 6933.166805 6961.077232 6425.95001 5755.383046 6367.992581 9338.222926 7084.226038 7700.195046 0.862203708 0.895581161 0.900388466 0.904013105 0.834517823 0.747433411 0.826991075 1.212725505 0.920006051 1 12.91067927 -9.341767119 0.949348279 1.003365381 0.886913203 0.018414023 0.117844276 1.055553845 1.623753444 0.087672607 0.020510221 4.55E-10 9.341767119 -0.116452178 AS(ph)VSQTSPQSASSPR ddPTM_HeLa_Curcumin_4h_R1 2 ASVSQTSPQSASSPR 15 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 0 AS(0.964)VS(0.036)QTSPQSASSPR;AS(0.835)VS(0.161)QT(0.003)SPQSASSPR ; 165.24 7.56E-07 9968000 1713.16 1569.59 1361.68 1754.92 1839.62 1538.09 1143.98 720.96 1841.65 1912 TRUE FALSE FALSE 1577.561578 1705.258366 1412.145059 1747.658606 1817.683733 1219.072796 1176.077 940.7773851 1639.625603 1978.441858 0.797375759 0.861919879 0.713766267 0.883351006 0.918745085 0.616178227 0.594446077 0.475514295 0.828745912 1 10.95014895 -3.613811382 0.290213728 0.939098047 4.77E-46 0.657545549 0.091574828 5.411770408 0.252002029 0.045890548 1.93038852 0.000243326 3.613811382 -0.939098047 ADVVPQQADPEFPRAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 ADVVPQQADPEFPRASPR 18 1 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 0 ADVVPQQADPEFPRAS(1)PR;ADVVPQQADPEFPRAS(1)PR ; 126.1 9.93E-05 377650000 10685.6 8152.3 8939.6 9945 8489.4 7167.3 3688.1 2152.62 11134 8194.1 TRUE FALSE FALSE 9839.823485 8856.948486 9270.90944 9903.850225 8388.16945 5680.721188 3791.57816 2808.943929 9912.628056 8478.844365 1.160514695 1.044593827 1.093416631 1.168066048 0.989305746 0.669987671 0.447181007 0.331288535 1.16910131 1 13.04965193 -5.04620943 1.747203404 1.083455093 0.351647894 0.961699231 0.05770102 0.059939643 0.341346296 0.010185185 0.043560036 8.99E-06 5.04620943 -0.731807199 down AS(ph)WESLDEEWR ddPTM_HeLa_Curcumin_4h_R1 1 ASWESLDEEWR 11 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 0 AS(0.998)WES(0.002)LDEEWR 125.36 0.0035015 2488000 1233.1 1074 1025.9 1008.7 875.86 1004.1 827.28 760.78 1127.7 981.75 TRUE FALSE FALSE 1135.498834 1166.831774 1063.920756 1004.526267 865.4159415 795.8383415 850.4912503 992.7383198 1003.994131 1015.865739 1.117764671 1.148608255 1.047304496 0.988837627 0.851899919 0.783408979 0.837208321 0.977233783 0.988313802 1 9.988494027 -5.930822319 2.787498861 1.064458767 0.854125312 0.679384372 0.063958017 0.122430134 1.930729673 0.010606608 0.020327883 1.17E-06 5.930822319 -0.210333456 AS(ph)WESLDEEWRAPQAGSR ddPTM_HeLa_Curcumin_4h_R1 2 ASWESLDEEWRAPQAGSR 18 1 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 0 AS(0.995)WES(0.005)LDEEWRAPQAGSR;AS(0.997)WES(0.003)LDEEWRAPQAGSR ; 127.67 8.86E-05 43473000 2168.6 1740.15 1575.97 1823.13 1390.4 2238.8 1662.46 1026.13 2206.7 1898.62 TRUE FALSE FALSE 1996.953022 1890.560812 1634.376835 1815.586371 1373.820388 1774.447644 1709.104153 1338.992313 1964.630531 1964.596904 1.016469596 0.962314869 0.831914594 0.924152109 0.699288686 0.903212074 0.869951566 0.681560839 1.000017117 1 10.94001762 -6.726696722 1.411794568 1.009417069 0.811899084 0.58464541 0.073580852 0.189657404 0.76373057 0.012085536 0.018180596 1.88E-07 6.726696722 -0.197517986 ASAAFSSVGSVITK ddPTM_HeLa_Curcumin_4h_R1 1 ASAAFSSVGSVITK 14 0 H0YC42;P55327-2;P55327;P55327-3;P55327-4;P55327-7;P55327-5;P55327-6 H0YC42 TPD52 Tumor protein D52 0 0 174.73 1.50E-05 1061500 759 750.38 640.33 707.9 758.11 992.01 671.73 890.12 822.53 679.61 FALSE FALSE TRUE 698.9243491 815.2395036 664.0611931 704.9708974 749.0700334 786.2559437 690.5769359 1161.51349 732.3005169 703.2263969 0.993882414 1.159284559 0.944306408 1.00248071 1.065190437 1.11806944 0.982012249 1.651692109 1.041343897 1 9.457845416 -4.259547931 24.99948585 1.016554102 1.651692323 0.892414457 0.064075236 35.70734986 471911.203 0.008616879 0.074787269 5.50E-05 4.259547931 0.635138221 ASAGPQPLLVQSCK ddPTM_HeLa_Curcumin_4h_R1 1 ASAGPQPLLVQSCK 14 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 159.5 0.00048468 1735800 1215.8 1170.2 1094.8 1306.1 1045.1 775.25 814.49 875.91 1212.9 1169 FALSE FALSE TRUE 1119.568147 1271.346874 1135.374251 1300.695704 1032.637865 614.4544111 837.3423973 1142.970927 1079.847905 1209.622663 0.925551564 1.051027657 0.938618534 1.075290456 0.853685944 0.507971973 0.692234383 0.944898737 0.892714677 1 10.24034136 -5.519346796 22.5022753 0.975467259 0.707433933 0.535040812 0.111076068 20.47931847 130473.1759 0.014981008 0.030565639 3.02E-06 5.519346796 -0.268033327 QGS(ph)PTPALPEK ddPTM_HeLa_Curcumin_4h_R1 1 QGSPTPALPEK 11 0 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0;H0Y4U1 A0A087WWW7 TNS1 Tensin-1 1 0 QGS(0.897)PT(0.103)PALPEK 101.6 0.010117 4298700 2325.8 2011.4 1975 1822.4 1582.3 2001 1197.7 829.29 2450.6 2214.3 TRUE FALSE FALSE 2141.710476 2185.256453 2048.195237 1814.859392 1563.432106 1585.970044 1231.304239 1082.136703 2181.775311 2291.24676 0.934735845 0.953741208 0.893921717 0.792083779 0.682349947 0.692186486 0.537394863 0.472291646 0.952221886 1 11.16191713 -5.04469786 0.46608032 0.986261451 0.307079203 0.970035195 0.030716556 0.271985813 0.062805447 0.007607796 0.089442642 9.02E-06 5.04469786 -0.679182248 down ASAGTPSLSAGVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 ASAGTPSLSAGVSPK 15 0 Q8TEK3;Q8TEK3-1 Q8TEK3 DOT1L "Histone-lysine N-methyltransferase, H3 lysine-79 specific" 1 0 ASAGTPSLS(0.001)AGVS(0.999)PK;ASAGTPSLSAGVS(1)PK ; 140.77 0.0005327 39003000 4021.5 3404.3 3787 3395.4 4048.9 4482.1 3083.1 1963.2 4259.6 3642.9 TRUE FALSE FALSE 3703.194032 3698.552523 3927.349551 3381.350734 4000.619512 3552.461936 3169.603488 2561.770643 3792.332537 3769.490504 0.982412352 0.981181016 1.041878086 0.897031238 1.061315716 0.94242496 0.840857268 0.679606605 1.006059714 1 11.88015382 -4.446906698 1.676335729 0.991805362 0.631167692 0.848059247 0.041970354 0.160043628 0.568354574 0.005313574 0.082275636 3.57E-05 4.446906698 -0.36063767 ASAISIK(ac)LGSSKPK ddPTM_HeLa_Curcumin_4h_R1 1 ASAISIKLGSSKPK 14 2 Q8WW12;Q8WW12-2 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 0 1 ASAISIK(0.999)LGSSK(0.001)PK 75.998 0.0091669 5921400 2818.2 2592.6 2853.9 2859.7 2368.1 4426.5 2624.2 3298.2 3006.3 2481.9 FALSE TRUE FALSE 2595.136496 2816.692792 2959.668045 2847.867319 2339.861954 3508.394003 2697.827989 4303.805997 2676.516411 2568.14584 1.010509783 1.0967807 1.15245326 1.108919624 0.911109454 1.366119458 1.050496411 1.675841741 1.042197982 1 11.32651142 -1 0.8035513 1.027875162 155.0890026 0.661060743 0.123164689 194.5248574 0.628442629 0.01780479 54608.68466 0.1 1 154.0611275 ASALLFSS(ph)DEEDQWNIPASQTHLASDSR ddPTM_HeLa_Curcumin_4h_R1 2 ASALLFSSDEEDQWNIPASQTHLASDSR 28 0 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;Q9Y4E1-5;Q641Q2;F8W7U3;E7ESD2;Q641Q2-2;A0A087WYF6 A0A0A0MR88;Q641Q2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 0 AS(0.001)ALLFS(0.211)S(0.788)DEEDQWNIPASQTHLASDSR;AS(0.002)ALLFS(0.234)S(0.763)DEEDQWNIPAS(0.001)QTHLASDSR ; 120.23 8.52E-11 25223000 3476.4 3371.7 2240.7 2317 4906.1 8160 4563.4 3911.9 5050.1 3183.3 TRUE FALSE FALSE 3201.239272 3663.134724 2323.742313 2307.412868 4847.597962 6467.524018 4691.436722 5104.620302 4496.116665 3293.919438 0.971863257 1.112089956 0.705464222 0.700506771 1.47168079 1.963473649 1.424271847 1.549710124 1.36497469 1 11.68558956 -5.620974353 5.777241558 0.956641495 1.637978869 0.664723139 0.219984248 0.072528664 3.568940757 0.02573632 0.052018766 2.39E-06 5.620974353 0.681337374 ASAPS(ph)PEDSVFADTGK ddPTM_HeLa_Curcumin_4h_R1 1 ASAPSPEDSVFADTGK 16 0 J3KQ40;O95759-2;O95759 J3KQ40 TBC1D8 TBC1 domain family member 8 1 0 AS(0.03)APS(0.816)PEDS(0.155)VFADTGK 123.02 0.00090934 0 922.3 805.43 816.68 715.78 681.79 1016.7 680.01 726.62 1084.7 810.9 TRUE FALSE FALSE 849.2989818 875.0477803 846.9468792 712.818292 673.6600995 805.8249594 699.0892504 948.1630931 965.7111238 839.0787146 1.012180344 1.042867332 1.009377147 0.849524937 0.802856857 0.96036873 0.833162894 1.130004941 1.150918391 1 9.712662347 -6.28531826 23.03527064 1.009519264 0.906896874 0.272121059 0.096639816 284.0500057 274014.2846 0.012180476 0.018615351 5.18E-07 6.28531826 -0.102622391 IEVEADGQTEEILDS(ph)QNLNSRRSPVPAQIAITVPK ddPTM_HeLa_Curcumin_4h_R1 1 IEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPK 35 2 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 0 IEVEADGQT(0.028)EEILDS(0.598)QNLNS(0.12)RRS(0.103)PVPAQIAIT(0.151)VPK 46.31 0.0045481 3468400 2171.3 1620.5 1964.1 1656.6 1433.4 1551.9 857.11 710.16 2239.3 2161.4 TRUE FALSE FALSE 1999.439314 1760.568799 2036.891274 1649.745428 1416.307641 1230.018446 881.1581998 926.6845148 1993.654392 2236.508489 0.894000324 0.787195223 0.910746051 0.737643267 0.633267277 0.549972626 0.39398831 0.414344287 0.891413738 1 11.12703252 -5.040853808 0.398008213 0.979273422 0.125819453 0.927585951 0.054845594 0.460445331 0.075663098 0.014880306 0.169462038 9.10E-06 5.040853808 -0.853453969 down ASAS(ph)PGENDSGTGGEEPQR ddPTM_HeLa_Curcumin_4h_R1 2 ASASPGENDSGTGGEEPQR 19 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 0 AS(0.019)AS(0.981)PGENDSGT(0.001)GGEEPQR;AS(0.003)AS(0.996)PGENDS(0.001)GTGGEEPQR ; 160.02 2.07E-05 12656800 3731 2940.9 3203.4 3829.5 3174.9 3246.4 3191.2 2259.3 4231.9 3865 TRUE FALSE FALSE 3435.687413 3195.098292 3322.120822 3813.654544 3137.041391 2573.060046 3280.736483 2948.150169 3767.671158 3999.308462 0.859070373 0.798912692 0.830673816 0.953578495 0.784395958 0.643376241 0.820325942 0.737164987 0.94208066 1 11.96553484 -13.52287874 0.063169623 1.798542437 0.478901325 0.544216056 0.068743309 134.8240487 0.666495954 16.39785232 2.833613452 3.00E-14 13.52287874 -1.319641112 ASAS(ph)PSTSSTSSRPK ddPTM_HeLa_Curcumin_4h_R1 1 ASASPSTSSTSSRPK 15 1 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;F5H858 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 0 AS(0.081)AS(0.918)PS(0.001)TSSTSSRPK 211.82 2.34E-09 11966000 2587.2 1878.2 2020.6 2222.5 2216.1 3025.4 2187.8 1047.8 2558.6 2044.4 TRUE FALSE FALSE 2382.42039 2040.543239 2095.485214 2213.303884 2189.674455 2397.897937 2249.18378 1367.269397 2277.927981 2115.442748 1.126204144 0.964593932 0.990565788 1.046260357 1.035090388 1.133520602 1.063221296 0.646327771 1.076809091 1 11.04674393 -4.260498834 24.71305408 1.052357717 0.646327621 0.84167178 0.052301044 22.18788474 582884.3849 0.008503585 0.069310057 5.49E-05 4.260498834 -0.406030096 ASASGSGAQVGGPISSGS(ph)SASSVTVTR ddPTM_HeLa_Curcumin_4h_R1 1 ASASGSGAQVGGPISSGSSASSVTVTR 27 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 0 ASASGSGAQVGGPIS(0.009)S(0.022)GS(0.441)S(0.441)AS(0.053)S(0.022)VT(0.009)VT(0.003)R 75.114 9.90E-05 10740000 992.19 993.93 971.23 1051.7 1132.2 1223.1 1222.5 953.48 1125.3 1356.9 TRUE FALSE FALSE 913.6571145 1079.84088 1007.224638 1047.348344 1118.699254 969.4152728 1256.80006 1244.191663 1001.857405 1404.052174 0.650728749 0.769088856 0.717369808 0.745946884 0.796764732 0.690441061 0.895123474 0.886143468 0.713547134 1 10.45538083 -9.489516451 1.23257805 1.000026576 0.756278687 0 0.114257553 0.277328773 0.75377545 0.056854462 0.013853723 3.24E-10 9.489516451 -0.243747889 ASATS(ph)ATLELDR ddPTM_HeLa_Curcumin_4h_R1 2 ASATSATLELDR 12 0 O43294;H3BQC4;O43294-2;H3BSN4 O43294 TGFB1I1 Transforming growth factor beta-1-induced transcript 1 protein 1 0 ASAT(0.03)S(0.944)AT(0.026)LELDR;ASAT(0.095)S(0.859)AT(0.046)LELDR ; 141.37 0.0011214 17862900 3060 2952.6 2292.6 3239.9 3447.1 3836.6 3434.2 1978.09 3385.5 2936.8 TRUE FALSE FALSE 2817.797771 3207.809587 2377.565773 3226.494152 3405.995584 3040.845913 3530.554409 2581.200535 3014.11912 3038.853581 0.927256841 1.0555986 0.782389052 1.061747158 1.120815957 1.000655619 1.161804712 0.849399442 0.991860595 1 11.56931145 ASAVSELS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 6 ASAVSELSPR 10 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 ASAVSELS(1)PR;ASAVSELS(1)PR;ASAVSELS(1)PR;ASAVSELS(1)PR;ASAVSELS(1)PR;ASAVSELS(1)PR ;;;;; 135.1 0.0021986 17064328000 13551.63 15747 10510.4 13054 12219.15 13758.88 11421.65 13175.77 13894.5 12978.4 TRUE FALSE FALSE 12479.00419 17108.10051 10899.92467 12999.98601 12073.44462 10905.13319 11742.11076 17193.00162 12370.30811 13429.39843 0.929230319 1.273929029 0.811646532 0.968024448 0.899030934 0.812034377 0.874358656 1.280251063 0.921136429 1 13.71310706 ASAVSELSPR ddPTM_HeLa_Curcumin_4h_R1 1 ASAVSELSPR 10 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 0 0 128.27 0.0023153 0 2895.9 2414.5 2289.3 2603.3 2376.6 2985.7 2584 2388.2 2759 2658.2 FALSE FALSE TRUE 2666.686459 2623.198621 2374.143472 2592.528234 2348.260597 2366.432164 2656.500086 3116.351186 2456.344603 2750.572252 0.969502422 0.953691952 0.863145286 0.942541405 0.853735289 0.860341757 0.965799056 1.132982849 0.893030387 1 11.42551608 -7.43243075 1.823515346 0.9886699 0.930451683 0 0.082120781 0.598484791 3.857580359 0.014848299 0.016509101 3.69E-08 7.43243075 -0.058218217 ASDPAS(ph)PHIGR ddPTM_HeLa_Curcumin_4h_R1 2 ASDPASPHIGR 11 0 O95425-3;A0A6I8PIX7;O95425-2;O95425;O95425-4 O95425-3 SVIL Supervillin 1 0 ASDPAS(1)PHIGR;ASDPAS(1)PHIGR ; 132.03 0.0011304 68154000 12849.1 9734.2 9921.1 10451 11235.2 14825.8 9992.5 4457.4 11991.6 9863.5 TRUE FALSE FALSE 11832.08018 10575.58087 10288.78469 10407.75653 11101.22758 11750.76196 10272.86266 5816.440741 10676.15148 10206.25589 1.159296837 1.036186138 1.0080861 1.019742856 1.087688541 1.15132935 1.006526072 0.569889762 1.046039958 1 13.3171661 -4.270803384 3.802893292 1.070456799 0.523835623 0.884618995 0.053077649 0.07159483 2.002704215 0.009439542 0.107590653 5.36E-05 4.270803384 -0.546621176 ASDPQS(ph)PPQVSR ddPTM_HeLa_Curcumin_4h_R1 1 ASDPQSPPQVSR 12 0 Q7L7X3-2;Q7L7X3-3;Q7L7X3 Q7L7X3-2 TAOK1 Serine/threonine-protein kinase TAO1 1 0 ASDPQS(0.996)PPQVS(0.004)R 154.13 0.00037494 52282000 4438.9 3697.5 3840.3 4378.2 4323.1 5793.6 3706.4 2808.7 5050.9 3397.6 TRUE FALSE FALSE 4087.556381 4017.095424 3982.624896 4360.084168 4271.549856 4591.942053 3810.391609 3665.0597 4496.828907 3515.666347 1.16266903 1.142627038 1.132822203 1.240187133 1.215004336 1.306137045 1.083831977 1.04249361 1.279082957 1 11.77958244 -9.087083742 0.582060087 0.9802941 1.17486907 0 0.112456818 0.833980406 0.445788621 0.085532464 0.018076019 8.18E-10 9.087083742 0.19457497 ASDSELER ddPTM_HeLa_Curcumin_4h_R1 1 ASDSELER 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 115.49 0.0034503 1558600 1546.8 1519.8 1487.5 1401.9 1634 2147.1 1420.1 1253.5 1648.9 1613.6 FALSE FALSE TRUE 1424.369148 1651.16474 1542.628059 1396.099309 1614.515617 1701.767257 1459.944184 1635.68638 1468.019795 1669.67248 0.853082964 0.988915347 0.923910574 0.836151596 0.96696546 1.019222199 0.874389559 0.97964505 0.879226203 1 10.70534942 -3.942464604 17.95806984 0.931828314 1.495799395 0.056363146 0.061856581 27384538.84 158209415.8 0.009448592 573652507.3 0.000114166 3.942464604 0.563971081 ASDSGPSSSSSSSS(ph)SPPR ddPTM_HeLa_Curcumin_4h_R1 2 ASDSGPSSSSSSSSSPPR 18 0 Q16643-3 Q16643-3 DBN1 Drebrin 1 0 ASDS(0.027)GPS(0.004)S(0.049)S(0.049)S(0.212)S(0.026)S(0.109)S(0.109)S(0.337)S(0.079)PPR;ASDSGPS(0.001)S(0.001)S(0.001)S(0.001)S(0.002)S(0.016)S(0.114)S(0.841)S(0.024)PPR ; 145.94 1.10E-06 1748100 1876.03 1902.73 2020.34 1857.65 1927.98 2175.5 1747.63 1657.99 2146.52 1603.02 TRUE FALSE FALSE 1727.540246 2067.193503 2095.215578 1849.963537 1904.990098 1724.276777 1796.663794 2163.503519 1911.052126 1658.724826 1.041486942 1.246254635 1.263148381 1.115292608 1.148466622 1.039519485 1.083159646 1.30431732 1.152121254 1 10.69585885 -7.410946532 6.074184328 1.018060518 1.163246957 0.180808929 0.089101175 0.171371648 8.088062748 0.013877467 0.015775213 3.88E-08 7.410946532 0.145186439 ASDSGPSSSSSSSSS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 1 ASDSGPSSSSSSSSSPPR 18 0 Q16643-3 Q16643-3 DBN1 Drebrin 1 0 ASDSGPSSSSSSSS(0.098)S(0.901)PPR 189.52 8.07E-09 5598200 2741.4 2053.6 2080.3 2416.7 2546 2952.6 2148.7 1942.4 2119.6 2104.3 TRUE FALSE FALSE 2524.415297 2231.104033 2157.397748 2406.700336 2515.640613 2340.197477 2208.986739 2534.628818 1887.085183 2177.424268 1.159358483 1.024652873 0.990802656 1.105296919 1.155328637 1.074754935 1.014495324 1.164049127 0.866659388 1 11.08840683 TGSEPALS(ph)PAVVRR ddPTM_HeLa_Curcumin_4h_R1 2 TGSEPALSPAVVRR 14 1 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 0 TGSEPALS(1)PAVVRR;T(0.002)GSEPALS(0.998)PAVVRR ; 79.514 0.0091597 32499100 10153.6 6862.6 7470.9 8930.3 5432.5 7184.2 3041.49 1225.79 12149.3 9601.8 TRUE FALSE FALSE 9349.931846 7455.772565 7747.778126 8893.348785 5367.720986 5694.115937 3126.826024 1599.527728 10816.55219 9935.461835 0.941066656 0.750420332 0.779810567 0.895111766 0.54025883 0.573110343 0.314713707 0.160991784 1.088681368 1 13.27837132 -5.039272949 0.504053675 0.978253833 3.94E-18 0.90239087 0.089822232 0.43136855 0.118471611 0.018312479 0.21640243 9.14E-06 5.039272949 -0.978253833 down ASEAAS(ph)PLPDS(ph)PGDKLVIVK ddPTM_HeLa_Curcumin_4h_R1 1 ASEAASPLPDSPGDKLVIVK 20 1 Q68CZ2;Q68CZ2-2 Q68CZ2 TNS3 Tensin-3 2 0 AS(0.216)EAAS(0.844)PLPDS(0.94)PGDKLVIVK 57.802 0.008431 0 2090.2 1587.2 1542.3 1865.3 2053.6 3103.7 2576.3 1129.6 2404.1 1431.8 TRUE FALSE FALSE 1924.758464 1724.390496 1599.458995 1857.581883 2029.112161 2459.957634 2648.584044 1474.00984 2140.376245 1481.554943 1.299147543 1.16390587 1.079581288 1.253805599 1.369582796 1.66038907 1.787705583 0.994907308 1.444682328 1 10.53289641 -5.737379551 2.492050302 1.143923334 1.509903945 0.206332555 0.226351159 0.227090272 2.877308355 0.031470535 0.066991017 1.83E-06 5.737379551 0.365980612 ALPS(ph)EDEEGQDDKDFYLR ddPTM_HeLa_Curcumin_4h_R1 1 ALPSEDEEGQDDKDFYLR 18 1 Q8NF91;Q8NF91-4;A0A0C4DG40;E7ENN3;Q8NF91-11;H0Y325;A0A5F9ZH87;F8WAI0;Q5JV20;A0A5F9ZHE1;H0Y326;A0A5F9ZH86;Q8NF91-3;Q8NF91-9;Q8NF91-8;Q8NF91-2;A0A5F9ZHB2 Q8NF91 SYNE1 Nesprin-1 1 0 ALPS(1)EDEEGQDDKDFYLR 98.804 0.00071793 16854000 2364.1 1639.7 2279.6 2349.5 1787.1 2090.5 769 729.21 2962 2201.9 TRUE FALSE FALSE 2176.97899 1781.428362 2364.083981 2339.778392 1765.79 1656.906735 790.5760703 951.5427721 2637.076011 2278.415861 0.955479211 0.781871471 1.037599861 1.026932103 0.775007772 0.72721875 0.346984975 0.417633492 1.157416456 1 11.15381538 -5.037323786 1.447589238 0.968555484 0.347243089 0.829398892 0.105501738 0.109070152 0.404252931 0.012546156 0.06376857 9.18E-06 5.037323786 -0.621312395 down TCPSLS(ph)PTSPLNNK ddPTM_HeLa_Curcumin_4h_R1 1 TCPSLSPTSPLNNK 14 0 O75925;O75925-2 O75925 PIAS1 E3 SUMO-protein ligase PIAS1 1 0 T(0.005)CPS(0.183)LS(0.526)PT(0.262)S(0.024)PLNNK 146.96 0.00059024 10379000 2022.1 1862.8 1576.4 1924.9 1902.2 1495.1 1118.1 561.66 2139.8 1800.6 TRUE FALSE FALSE 1862.048651 2023.812132 1634.822771 1916.935274 1879.517507 1184.999407 1149.470877 732.9075484 1905.069294 1863.170716 0.999397766 1.086219375 0.877441212 1.028856485 1.008773641 0.636012254 0.6169434 0.393365751 1.022487782 1 10.86354415 -5.030341068 1.687117787 1.002365999 0.461517373 0.897985543 0.070994643 0.078443833 0.412690451 0.009395714 0.042153768 9.33E-06 5.030341068 -0.540848625 down ASEAASPLPDS(ph)PGDKLVIVK ddPTM_HeLa_Curcumin_4h_R1 1 ASEAASPLPDSPGDKLVIVK 20 1 Q68CZ2;Q68CZ2-2 Q68CZ2 TNS3 Tensin-3 1 0 ASEAASPLPDS(1)PGDKLVIVK 81.696 0.0010789 59533000 2705.3 2034.7 1804.6 2377.4 2013.2 3115.3 2578.9 1229.7 2579 2027.4 TRUE FALSE FALSE 2491.17265 2210.570402 1871.480063 2367.562949 1989.193905 2469.151663 2651.256993 1604.629869 2296.090152 2097.851999 1.187487321 1.053730388 0.892093467 1.12856529 0.948205072 1.1769904 1.263796013 0.764891837 1.094495776 1 11.03469719 -7.018773343 24.58116387 1.090223739 1.041125291 0.036165026 0.141582373 2269.585779 2971717.489 0.02378226 0.029404247 9.58E-08 7.018773343 -0.049098448 SATT(ph)TGSPGTEK ddPTM_HeLa_Curcumin_4h_R1 2 SATTTGSPGTEK 12 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 0 S(0.001)AT(0.025)T(0.378)T(0.378)GS(0.22)PGTEK;SAT(0.004)T(0.444)T(0.444)GS(0.108)PGTEK ; 203.39 1.98E-08 201167000 7833.1 9472.4 8017.4 6744.4 6544 6235.1 4064.8 1865.06 7155.2 8044.5 TRUE FALSE FALSE 7213.10187 10291.15205 8314.531897 6716.49346 6465.967074 4941.869976 4178.847348 2433.708208 6370.292461 8324.045776 0.866537987 1.236316129 0.998857061 0.806878487 0.776781777 0.593686064 0.502021188 0.292370834 0.765288014 1 13.02306918 -5.021265743 0.904117573 0.964297188 0.266234432 0.78073402 0.120532504 0.292606398 0.334955019 0.018458475 0.155004955 9.52E-06 5.021265743 -0.698062756 down ASEDTTSGS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 4 ASEDTTSGSPPK 12 0 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 0 ASEDTTSGS(1)PPK;ASEDTTSGS(1)PPK;ASEDTTSGS(1)PPK;ASEDT(0.001)T(0.004)S(0.004)GS(0.991)PPK ;;; 168.76 0.00012765 237232000 11942.1 11179 13023.5 12827.2 11110.2 13511.3 11416.6 10359.4 13348.1 12578.3 TRUE FALSE FALSE 10996.87018 12145.26295 13506.16237 12774.12445 10977.71812 10708.90408 11736.91907 13517.93337 11883.84683 13015.39499 0.84491252 0.933145937 1.037706683 0.98146268 0.843441027 0.822787482 0.901772023 1.038611074 0.91306079 1 13.66793147 -5.769288401 24.99527099 0.93825466 0.896028164 0.082442653 0.07310007 466.6254196 1485974.467 0.012856265 0.023606228 1.70E-06 5.769288401 -0.042226496 ASEDTTSGS(ph)PPKK ddPTM_HeLa_Curcumin_4h_R1 5 ASEDTTSGSPPKK 13 1 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 0 ASEDT(0.022)T(0.011)S(0.13)GS(0.837)PPKK;ASEDT(0.12)T(0.01)S(0.007)GS(0.863)PPKK;AS(0.009)EDT(0.068)T(0.007)S(0.005)GS(0.912)PPKK;ASEDT(0.007)T(0.005)S(0.04)GS(0.948)PPKK;ASEDT(0.201)T(0.02)S(0.115)GS(0.664)PPKK ;;;; 157.2 1.02E-06 1754745800 20754.5 17930.5 19430.2 20262.8 21824.9 25171.2 18988.9 17668.7 24273.3 23274.9 TRUE FALSE FALSE 19111.75942 19480.33252 20150.3003 20178.9579 21564.65232 19950.40938 19521.67743 23055.80529 21610.57972 24083.70104 0.793555749 0.808859589 0.836677896 0.837867812 0.895404418 0.828378053 0.810576306 0.957319859 0.897311409 1 14.55576949 -9.382622866 1.086455494 1.000738314 0.840383585 0.295617159 0.054899375 0.262368209 0.550011393 0.032142783 0.008108353 4.14E-10 9.382622866 -0.160354729 ASEENLLSSSSVPSADRDS(ph)SPTTNSK ddPTM_HeLa_Curcumin_4h_R1 2 ASEENLLSSSSVPSADRDSSPTTNSK 26 1 B1AKL4;Q9NRA8;Q9NRA8-3;Q9NRA8-2 B1AKL4 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 0 ASEENLLSSSSVPSADRDS(0.482)S(0.482)PT(0.032)T(0.003)NSK;ASEENLLS(0.005)S(0.002)S(0.002)S(0.001)VPS(0.02)ADRDS(0.446)S(0.446)PT(0.056)T(0.023)NS(0.001)K ; 120.27 8.66E-09 196619000 4488.24 3809.87 3498.15 4091.9 4342.5 4925.6 3490.13 2456.47 4285.7 3671.58 TRUE FALSE FALSE 4132.991068 4139.178186 3627.794516 4074.968802 4290.718524 3903.975037 3588.053655 3205.436395 3815.569432 3799.167132 1.087867663 1.089496209 0.954892057 1.072595298 1.129383987 1.027587074 0.944431643 0.843720817 1.004317341 1 11.89146746 -4.522567563 2.274899597 1.047717426 0.839358054 0.639257276 0.048678064 0.193875505 1.65122287 0.007431383 0.064183214 3.00E-05 4.522567563 -0.208359372 YTDNSEKPSGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 YTDNSEKPSGKR 12 2 Q6W2J9-4;Q6W2J9-2;Q6W2J9;H7C231;H7C2V9;H7BZ37 Q6W2J9-4 BCOR BCL-6 corepressor 0 1 YTDNSEKPSGK(1)R 83.137 0.0085537 2443700 2341.7 2225.3 1880.6 1536 1835.4 2659.5 836.38 298.45 2064 1947.4 FALSE TRUE FALSE 2156.351974 2417.645016 1950.29669 1529.644439 1813.514054 2107.889721 859.8465718 389.4460311 1837.584364 2015.072005 1.070111623 1.199780956 0.967854591 0.759101628 0.899974814 1.046061737 0.426707616 0.193266558 0.911919951 1 10.97661568 -4.665103465 3.493051265 1.013812709 0.233580755 0.842967221 0.116926336 0.061089975 1.401302816 0.017023167 0.076530441 2.16E-05 4.665103465 -0.780231954 down ASEKPPERVQK ddPTM_HeLa_Curcumin_4h_R1 2 ASEKPPERVQK 11 2 A6NHN7;A6NHB5;A6NL54;A6NC58 A6NHN7 ZMYM3 0 0 ; ; 104.17 0.0088062 13120600 3561.3 3347.8 3437.2 3663.6 3851.2 5285.5 4187.4 2622 3547.9 2944.8 FALSE FALSE TRUE 3279.419347 3637.168914 3564.585656 3648.440994 3805.276955 4189.22772 4304.887174 3421.43573 3158.704246 3047.131581 1.076231617 1.193636972 1.169816781 1.197336215 1.248806248 1.374810247 1.412767076 1.122838197 1.036615638 1 11.57323608 -6.821549449 0.568358373 1.012035815 1.315808931 0.634406294 0.077512958 0.313801603 0.216298399 0.02168001 0.036742552 1.51E-07 6.821549449 0.303773116 ASEPLLS(ph)PPPFGESR ddPTM_HeLa_Curcumin_4h_R1 2 ASEPLLSPPPFGESR 15 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 0 ASEPLLS(1)PPPFGESR;ASEPLLS(1)PPPFGESR ; 221.78 1.12E-14 40202000 5161.3 4199.1 4449.4 4431.5 4184.8 6718.3 6001.3 5141.1 5359.7 4843.2 TRUE FALSE FALSE 4752.777659 4562.051493 4614.298678 4413.163627 4134.898993 5324.848849 6169.680326 6708.597723 4771.754319 5011.50084 0.948374112 0.910316418 0.920741875 0.880607181 0.825081972 1.062525782 1.231104319 1.338640447 0.952160734 1 12.29102701 -4.780881431 2.576113639 0.949703433 1.316398476 0.878469477 0.053514206 0.08241444 1.067008953 0.0089212 0.040965575 1.66E-05 4.780881431 0.366695044 ASES(ph)SSEEKDDYEIFVK ddPTM_HeLa_Curcumin_4h_R1 1 ASESSSEEKDDYEIFVK 17 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 0 AS(0.019)ES(0.343)S(0.312)S(0.312)EEKDDY(0.013)EIFVK 59.673 0.015533 33934000 1659.7 1809 1978.1 2081.7 1837.6 2472.6 1971.8 691.1 2149.7 1610.7 TRUE FALSE FALSE 1528.332994 1965.361899 2051.410126 2073.086477 1815.68782 1959.754888 2027.123401 901.8132086 1913.883288 1666.671705 0.916997024 1.179213575 1.230842355 1.243848126 1.089409399 1.175849378 1.216270364 0.541086289 1.148326502 1 10.70275424 -7.266142118 24.80439308 0.96080415 1.114837618 0 0.204135571 553.5236653 2919532.454 0.031502497 0.036669201 5.42E-08 7.266142118 0.154033469 ASESSKPWPDATYGTGS(ph)ASR ddPTM_HeLa_Curcumin_4h_R1 1 ASESSKPWPDATYGTGSASR 20 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 ASESSKPWPDAT(0.002)Y(0.001)GT(0.234)GS(0.604)AS(0.159)R 72.513 0.0023825 35317000 1676.3 1664.7 1712.3 1945.1 1943.4 3405.4 3258.1 2058.8 1971.2 1468.8 TRUE FALSE FALSE 1543.619086 1808.58925 1775.759344 1937.051692 1920.226224 2699.081653 3349.513517 2686.518642 1754.964292 1519.840691 1.015645321 1.18998607 1.168385184 1.274509693 1.263439146 1.775897744 2.203858298 1.767631739 1.154702794 1 10.56970439 -5.352242026 1.195875866 1.034714825 2.04225273 0.853298252 0.144292595 0.115492199 0.299504038 0.021275771 0.087283327 4.44E-06 5.352242026 1.007537905 ASESSKPWPDATYGTGSASR ddPTM_HeLa_Curcumin_4h_R1 1 ASESSKPWPDATYGTGSASR 20 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 0 0 94.325 0.0028075 1997300 815.15 865.16 690.35 780.03 591.49 812.16 880.66 636.66 762.15 699.97 FALSE FALSE TRUE 750.6300174 939.9405753 715.9349783 776.8024425 584.4368681 643.7088611 905.3689494 830.7747032 678.5440518 724.2939054 1.036361085 1.297733652 0.988459206 1.072496174 0.806905682 0.888739856 1.250002164 1.147013246 0.936835236 1 9.500431426 -1.02290562 0.007935589 0.032222891 2.167958485 0.042604006 0.14350479 72792.9235 45.32826551 5430.573923 6846.609446 0.09486246 1.02290562 2.135735594 ASET(ph)PPPVAQPKPEAPHPGLETTLQER ddPTM_HeLa_Curcumin_4h_R1 1 ASETPPPVAQPKPEAPHPGLETTLQER 27 1 Q6P1N0;Q6P1N0-2 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 1 0 AS(0.095)ET(0.905)PPPVAQPKPEAPHPGLETTLQER 86.955 8.47E-06 29051000 1821 1515.2 1596 1519 1603.7 2087.2 1685.1 1285.9 1972.2 1796.8 TRUE FALSE FALSE 1676.865928 1646.167136 1655.149164 1512.71478 1584.576925 1654.291192 1732.379371 1677.96499 1755.854594 1859.238666 0.901909991 0.885398505 0.89022953 0.813620547 0.852271929 0.889768066 0.931768149 0.902501126 0.944394405 1 10.86049626 -8.718882579 0.63752706 1.001772521 0.879185903 0.511578101 0.033610323 0.370720173 0.288972742 0.023087237 0.007955823 1.91E-09 8.718882579 -0.122586617 ASFDHS(ph)PDSLPLR ddPTM_HeLa_Curcumin_4h_R1 1 ASFDHSPDSLPLR 13 0 H0Y6H0;Q8NB78;Q8NB78-2 H0Y6H0 KDM1B Lysine-specific histone demethylase 1B 1 0 AS(0.004)FDHS(0.993)PDS(0.003)LPLR 78.249 0.0077239 0 1984.3 1670.9 1647 1715 2648.8 3869.5 1699.6 1100.4 2338.9 1685.1 TRUE FALSE FALSE 1827.240561 1815.325151 1708.039269 1707.903784 2617.21479 3066.922082 1747.286202 1435.906894 2082.328522 1743.6571 1.047935722 1.041102147 0.979572916 0.979495214 1.500991675 1.75890207 1.002081316 0.823503024 1.194230518 1 10.76790064 -5.788544552 24.95992723 1.018417228 1.286958504 0.171436886 0.244978839 246.9424855 227397.5784 0.03614017 0.065521899 1.63E-06 5.788544552 0.268541276 ASGDPGASGMS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 ASGDPGASGMSPR 13 0 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 0 ASGDPGAS(0.004)GMS(0.996)PR;ASGDPGAS(0.01)GMS(0.99)PR;ASGDPGASGMS(1)PR ;; 115.24 0.0034351 189538000 23613.3 19818.1 20948 22796.7 22625.9 25184.3 20248.5 13429.5 23587.2 20434.6 TRUE FALSE FALSE 21744.28239 21531.08826 21724.35131 22702.3733 22356.10092 19960.79229 20816.61841 17524.09273 20999.74317 21144.70083 1.028356115 1.018273488 1.027413511 1.073667274 1.057290954 0.944009209 0.984483941 0.828769954 0.993144492 1 14.36800853 -3.596849489 1.081856098 1.020569484 0.311662245 0.768013747 0.031636058 2.194865453 0.733822413 0.004774133 2.531368033 0.000253017 3.596849489 -0.708907239 ASGEMAS(ph)AQYITAALR ddPTM_HeLa_Curcumin_4h_R1 3 ASGEMASAQYITAALR 16 0 A6NJA2;P54578-2;P54578-3;P54578 A6NJA2 USP14 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 14 1 0 AS(0.472)GEMAS(0.505)AQY(0.022)ITAALR;AS(0.002)GEMAS(0.984)AQY(0.014)ITAALR;AS(0.143)GEMAS(0.852)AQY(0.005)ITAALR ;; 136.81 0.00048763 71913200 5349.5 5444.8 6596.6 5467.5 7663.3 5142.1 6594.6 5457.4 5347.2 4716.5 TRUE FALSE FALSE 4926.08143 5915.42425 6841.075799 5444.876934 7571.920153 4075.570497 6779.626728 7121.336137 4760.625538 4880.398024 1.00936059 1.212078241 1.401745465 1.115662474 1.551496438 0.835089777 1.389154469 1.459171179 0.975458459 1 12.2527831 -7.188095684 3.69845936 1.003616282 1.28104294 0.327901168 0.189468525 0.200087423 5.323881251 0.029678796 0.036248411 6.48E-08 7.188095684 0.277426658 ASGGQDGAASSAGAAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 ASGGQDGAASSAGAAKR 17 1 O60287 O60287 URB1 Nucleolar pre-ribosomal-associated protein 1 0 1 ; ASGGQDGAASSAGAAK(1)R;ASGGQDGAASSAGAAK(1)R 104.09 0.000211 291630 221.422 224.08 345.34 105.44 149.92 406.7 268.296 272.398 386.73 49.19 FALSE TRUE FALSE 203.8962151 243.4484767 358.1386042 105.0037172 148.1323019 322.3458355 275.8236637 355.4508962 344.3066866 50.89934884 4.005870796 4.782938923 7.036211904 2.062967791 2.910298566 6.333005095 5.419001814 6.983407536 6.764461519 1 5.669575295 -8.679432294 0.30814461 1.56E-21 5.651029689 0 2.309801542 1.668926113 0.298635191 3.523741545 1.045937605 2.09E-09 8.679432294 5.651029689 ASGNYATVISHNPETK ddPTM_HeLa_Curcumin_4h_R1 2 ASGNYATVISHNPETK 16 0 E9PKZ0;P62917;G3V1A1 E9PKZ0 RPL8 60S ribosomal protein L8 0 0 ; ; 158.14 0.00036223 19145200 6174.7 5192.6 5092.4 5280.8 5807.8 7717.1 5697.9 4932.1 6452.1 5028 FALSE FALSE TRUE 5685.965979 5641.425206 5281.128824 5258.949449 5738.545778 6116.48647 5857.767739 6435.874585 5744.320772 5202.722626 1.092882782 1.084321732 1.015070225 1.010807192 1.102988991 1.175631859 1.125904293 1.237020508 1.104098985 1 12.34505108 -1 0.338908577 1.034669476 3.175593704 0.607273915 0.044486924 25.62437514 0.323589693 0.014357009 35.14646099 0.1 1 2.140924228 ASGNYATVISHNPETK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 ASGNYATVISHNPETKK 17 1 E9PKZ0;P62917;G3V1A1 E9PKZ0 RPL8 60S ribosomal protein L8 0 1 ; ASGNYATVISHNPETK(1)K;ASGNYATVISHNPETK(1)K 229.92 3.45E-37 9249000 3534.4 4577.7 2922.9 3069 6372.4 8592.6 5376.1 5366.8 8650.8 3497.2 FALSE TRUE FALSE 3254.648511 4973.37599 3031.225245 3056.301291 6296.413292 6810.397901 5526.938897 7003.112614 7701.828883 3618.72744 0.899390342 1.374343902 0.837649504 0.844579025 1.739952344 1.881986973 1.527315607 1.935241803 2.128325222 1 11.82126673 -5.754892152 24.98726542 0.970223676 1.761628257 0.257612616 0.405435454 43.15142934 164684.3046 0.024204465 0.047515232 1.76E-06 5.754892152 0.791404582 ASGPPVSELITK ddPTM_HeLa_Curcumin_4h_R1 2 ASGPPVSELITK 12 0 P10412;P16403;P16402 P10412;P16403;P16402 HIST1H1E;HIST1H1C;HIST1H1D Histone H1.4;Histone H1.2;Histone H1.3 0 0 ; ; 157.97 1.72E-05 7704500 3454 3178.3 3828.2 4766.3 3976.9 3534.8 3405.1 2228.43 3168.9 2694.14 FALSE FALSE TRUE 3180.612255 3453.01809 3970.07646 4746.578314 3929.478065 2801.642635 3500.637942 2907.868049 2821.279598 2787.761164 1.140919924 1.238634835 1.424109249 1.70264884 1.409546167 1.004979433 1.255716589 1.043083635 1.012023424 1 11.44489125 -7.507348014 1.559274963 1.048202651 1.310857792 0.275542383 0.1879294 0.377837925 1.826005012 0.040967422 0.044033315 3.11E-08 7.507348014 0.262655142 RLS(ph)ESQLSFR ddPTM_HeLa_Curcumin_4h_R1 1 RLSESQLSFR 10 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 0 RLS(0.999)ES(0.001)QLSFR 124.48 0.0017762 11316000 1056.8 802.27 852.33 936.47 1076.9 1575.5 1653.4 1729.9 1388.8 1009.1 TRUE FALSE FALSE 973.1531649 871.614644 883.9180996 932.5951353 1064.058671 1248.72354 1699.789954 2257.338547 1236.452115 1044.16615 0.931990723 0.834747079 0.846530123 0.893148217 1.019051107 1.19590502 1.627892222 2.161857619 1.184152651 1 10.02813558 -4.465242411 1.27055016 0.94097504 2.456588929 0.944586566 0.094052008 0.112441847 0.198433981 0.010297412 0.200203648 3.43E-05 4.465242411 1.515613889 up ASGQAFELILSPR ddPTM_HeLa_Curcumin_4h_R1 2 ASGQAFELILSPR 13 0 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 0 0 ; ; 154.23 0.0035292 2560460 1012.82 812.63 951.01 994.21 932.49 1365.93 1583.29 1809.86 1266.82 856.45 FALSE FALSE TRUE 932.6542283 882.8701162 986.2552672 990.0962225 921.3706658 1082.620721 1627.712856 2361.677982 1127.853015 886.2115738 1.052405832 0.996229504 1.112889175 1.117223304 1.039673474 1.221627829 1.836709093 2.664914398 1.272667892 1 9.791507358 -4.372467098 1.432957936 1.033818342 3.131348502 0.97018102 0.086819993 0.057161381 0.12186247 0.006881921 0.160697261 4.24E-05 4.372467098 2.09753016 up ASGS(ph)ENEGDYNPGR ddPTM_HeLa_Curcumin_4h_R1 2 ASGSENEGDYNPGR 14 0 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 1 0 AS(0.18)GS(0.82)ENEGDYNPGR;ASGS(1)ENEGDYNPGR ; 148.18 0.00055907 25928000 5151.1 4271.97 4705.2 4155.2 4014.46 4128.9 2792.9 1754.27 3660.21 4336.99 TRUE FALSE FALSE 4743.385 4641.220051 4879.578851 4138.006883 3966.590186 3272.519598 2871.261257 2289.138847 3258.69412 4487.70008 1.056974601 1.034209053 1.087322852 0.922077414 0.88388041 0.729219765 0.639806851 0.510091763 0.726139016 1 12.13176055 -5.071625842 0.925086942 1.032804152 0.484734359 0.699533685 0.102663293 0.11136558 0.139055003 0.006073084 0.046128087 8.48E-06 5.071625842 -0.548069793 ESYDAPPT(ph)PSGAR ddPTM_HeLa_Curcumin_4h_R1 1 ESYDAPPTPSGAR 13 0 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 0 ESYDAPPT(0.861)PS(0.139)GAR 203.85 1.96E-08 42523000 2274.5 2335.8 2059.2 2577.4 2419.2 4184.1 4616.6 5026.8 2280.8 2471.7 TRUE FALSE FALSE 2094.470925 2537.696144 2135.515763 2566.735402 2390.35262 3316.270495 4746.129371 6559.448179 2030.601946 2557.591391 0.8189232 0.9922211 0.834971439 1.003575243 0.934610833 1.296638121 1.855702747 2.564697474 0.793950884 1 11.32057008 -4.461632562 1.221538513 0.913644503 2.994233394 0.981409418 0.073883416 0.098472089 0.156317242 0.011524721 0.234480167 3.45E-05 4.461632562 2.080588891 up IPTPIVGVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 IPTPIVGVKR 10 1 G3XAH6;P51003;H0YJL4 G3XAH6 PAPOLA Poly(A) polymerase alpha 0 1 ; IPTPIVGVK(1)R;IPTPIVGVK(1)R 104.01 0.0024144 20877900 966.57 862.2 860.22 638.17 737.24 1421.93 1240.25 1442.68 1012.72 803.45 FALSE TRUE FALSE 890.0649646 936.7247261 892.1005099 635.5294216 728.4488945 1127.00569 1275.048077 1882.546491 901.6271497 831.3698277 1.070600514 1.126724467 1.073048937 0.764436476 0.876203189 1.355600903 1.533671339 2.264391163 1.084507905 1 9.69934658 -4.321939074 1.327111634 1.017551562 2.694333576 0.907065013 0.123920894 0.254548024 0.416057584 0.018789761 0.555982067 4.76E-05 4.321939074 1.676782014 up ASIANSDGPTAGS(ph)QTPPFK ddPTM_HeLa_Curcumin_4h_R1 2 ASIANSDGPTAGSQTPPFK 19 0 J3KP75;F6TH74;O75167-5;O75167-2;O75167;O75167-4;H9KVA6 J3KP75 PHACTR2 Phosphatase and actin regulator;Phosphatase and actin regulator 2 1 0 ASIANSDGPT(0.001)AGS(0.999)QTPPFK;ASIANSDGPTAGS(0.986)QT(0.014)PPFK ; 157.7 2.67E-05 27514000 12764.4 10470.8 10693.7 11402.7 12417.2 13594.6 11012.8 4635.6 11697.8 9962.9 TRUE FALSE FALSE 11754.08427 11375.8493 11090.01793 11355.51865 12269.133 10774.92672 11321.78953 6048.9731 10414.58061 10309.11003 1.140164789 1.103475398 1.075749303 1.101503293 1.190125332 1.045184956 1.098231515 0.586759971 1.010230813 1 13.33163217 -4.260252154 24.96101719 1.081363569 0.586759808 0.883341205 0.054301095 27.5093546 578302.5512 0.008721537 0.072301385 5.49E-05 4.260252154 -0.494603761 ASIGQS(ph)PGLPSTTFK ddPTM_HeLa_Curcumin_4h_R1 2 ASIGQSPGLPSTTFK 15 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 AS(0.002)IGQS(0.614)PGLPS(0.274)T(0.084)T(0.026)FK;ASIGQS(0.999)PGLPS(0.001)TTFK ; 209.89 6.63E-10 135370000 9233.9 6752.6 8819.8 8263.9 8506.7 11493.2 9892.6 10382.2 8641.5 7484.5 TRUE FALSE FALSE 8503.027071 7336.264655 9146.669547 8229.706171 8405.263158 9109.380765 10170.15973 13547.68499 7693.54907 7744.585818 1.097931803 0.947276566 1.181040505 1.062639935 1.085308286 1.176225686 1.313196079 1.749310461 0.993410009 1 12.91897237 -1.000000025 0.725879397 1.046533965 108.2061745 0.928612583 0.059081655 53.6845849 0.239995794 0.009530455 9386.577103 0.099999994 1.000000025 107.1596405 ASIHEAWTDGK ddPTM_HeLa_Curcumin_4h_R1 1 ASIHEAWTDGK 11 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75 O43707;P12814-4 ACTN4;ACTN1 Alpha-actinin-4;Alpha-actinin-1 0 0 87.713 0.015854 20604000 5426.3 3162.6 4684.6 3508.7 7442.8 9497.6 6832.2 5880.9 4109.9 3589.2 FALSE FALSE TRUE 4996.802629 3435.961052 4858.215397 3494.181929 7354.049471 7527.6907 7023.893144 7673.959338 3659.054252 3713.924433 1.345423882 0.925156425 1.308108306 0.940832802 1.980128999 2.026883109 1.891232111 2.066266957 0.985225822 1 11.85872875 -5.752541346 24.99954258 1.145274732 1.986546573 0.898434211 0.14854361 48.6382934 136651.0337 0.023221538 0.045897379 1.77E-06 5.752541346 0.841271841 ASLAS(ph)LDSNPSTNEK ddPTM_HeLa_Curcumin_4h_R1 2 ASLASLDSNPSTNEK 15 0 Q96BY6;H7C0I3;A0A2R8YD85;Q96BY6-3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 0 AS(0.288)LAS(0.379)LDS(0.327)NPS(0.006)T(0.001)NEK;AS(0.001)LAS(0.995)LDS(0.004)NPSTNEK ; 236.03 1.32E-21 4670100 3296.1 2722.4 3193.1 3728.7 3479.3 4224.1 3099.3 1173.13 3484 3119.9 TRUE FALSE FALSE 3035.210207 2957.712125 3311.439095 3713.271627 3437.81162 3347.974045 3186.258017 1530.811937 3101.813917 3228.316293 0.940183654 0.916177926 1.025748035 1.150219276 1.064893061 1.037065065 0.986972071 0.474182762 0.960814751 1 11.65656622 -4.261622233 7.188369573 0.994578659 0.467337337 0.858281005 0.064977194 0.032230496 13.79566452 0.010182157 0.082257911 5.47E-05 4.261622233 -0.527241322 ASLENSLR ddPTM_HeLa_Curcumin_4h_R1 2 ASLENSLR 8 0 P05783;F8VZY9;CON__H-INV:HIT000015463 P05783 KRT18 "Keratin, type I cytoskeletal 18" 0 0 ; ; 153.08 1.04E-05 21998000 6787.7 4730.9 5034.6 5196.6 6141.8 7155.1 4672.8 4041.1 6049.4 5486 FALSE FALSE TRUE 6250.446383 5139.817916 5221.186705 5175.097846 6068.563046 5671.051605 4803.906192 5273.212787 5385.795955 5676.638092 1.101082416 0.905433433 0.919767408 0.911648367 1.069041737 0.999015881 0.846259021 0.928932354 0.948765073 1 12.47082105 -7.255806599 24.97260601 1.047733363 0.941770269 0.168418317 0.068112731 389.0952479 1725031.888 0.011504669 0.013885315 5.55E-08 7.255806599 -0.105963094 ASLGS(ph)LEGEAEAEAS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 AS(0.002)LGS(0.998)LEGEAEAEAS(0.558)S(0.443)PK 90.379 0.006504 3939400 956.41 1486.9 690.07 1034.5 948.21 1080.4 917.31 645.58 1187.8 879.84 TRUE FALSE FALSE 880.7091393 1615.421011 715.6446012 1030.219513 936.903215 856.3128614 943.0472498 842.4143701 1057.501312 910.4143745 0.967371742 1.774379948 0.786064699 1.131594076 1.029095367 0.940574847 1.035843981 0.925308732 1.161560429 1 9.830379526 -5.417214454 6.580667659 1.044105227 0.974765484 0.012567445 0.252296772 1.190501269 64.23729089 0.034980402 0.078668916 3.83E-06 5.417214454 -0.069339743 ASLGS(ph)LEGEAEAEAS(ph)SPKGK ddPTM_HeLa_Curcumin_4h_R1 3 ASLGSLEGEAEAEASSPKGK 20 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 AS(0.133)LGS(0.867)LEGEAEAEAS(0.644)S(0.356)PKGK;AS(0.02)LGS(0.975)LEGEAEAEAS(0.612)S(0.393)PKGK;AS(0.009)LGS(0.989)LEGEAEAEAS(0.667)S(0.335)PKGK ;; 103.03 0.00028382 163053400 16271.5 13182.6 13192.8 15797.4 11443.7 21330 17265 6058.3 19560.7 14163 TRUE FALSE FALSE 14983.59361 14322.0452 13681.73677 15732.03454 11307.24135 16905.91756 17749.40943 7905.447781 17414.94015 14655.1632 1.02241056 0.977269582 0.93357792 1.073480679 0.771553425 1.153580983 1.211136935 0.539430894 1.188314311 1 13.83912141 -4.245451213 24.56428627 1.011244185 0.539430442 0.574825426 0.126622754 1179.527432 1812194.737 0.014574544 0.487597001 5.68E-05 4.245451213 -0.471813743 ASLGS(ph)LEGEAEAEASS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 AS(0.004)LGS(0.996)LEGEAEAEAS(0.093)S(0.907)PK;AS(0.003)LGS(0.997)LEGEAEAEAS(0.192)S(0.808)PK;ASLGS(1)LEGEAEAEAS(0.035)S(0.965)PK;AS(0.001)LGS(0.998)LEGEAEAEAS(0.346)S(0.656)PK ;;; 219.87 9.39E-26 516110000 20697.7 17644.1 21590.3 20435.3 22241.8 24806.3 25614.3 8387.5 20344.4 16099 TRUE FALSE FALSE 19059.4552 19169.17738 22390.45551 20350.74414 21976.58106 19661.19376 26332.96832 10944.81014 18112.67022 16658.43905 1.144132121 1.150718703 1.34409085 1.221647723 1.319246119 1.180254266 1.580758452 0.657012947 1.087296965 1 14.0239656 -8.06697481 0.735164917 1.018708521 1.232701029 0.069857314 0.220768413 0.811776495 0.965455738 0.073047166 0.049444412 8.57E-09 8.06697481 0.213992508 ASLGS(ph)LEGEAEAEASS(ph)PKGK ddPTM_HeLa_Curcumin_4h_R1 1 ASLGSLEGEAEAEASSPKGK 20 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 AS(0.007)LGS(0.993)LEGEAEAEAS(0.462)S(0.538)PKGK 90.601 0.00080469 62617000 6452.8 5343.3 5009.1 5689.5 4625.6 8707.1 7264 2613.2 8524.6 6113.8 TRUE FALSE FALSE 5942.054071 5805.151043 5194.741652 5665.958357 4570.442741 6901.149311 7467.80829 3409.95265 7589.472707 6326.254095 0.939268955 0.917628498 0.821140216 0.895626112 0.722456397 1.090874506 1.180447098 0.539016075 1.199678766 1 12.62713579 -7.901545563 0.986973724 0.986857846 0.893568949 0.125837903 0.181161884 1.129078159 2.335886145 0.043435852 0.036433129 1.25E-08 7.901545563 -0.093288897 ASLGS(ph)LEGEAEAEASSPK ddPTM_HeLa_Curcumin_4h_R1 5 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 AS(0.001)LGS(0.999)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK;AS(0.003)LGS(0.997)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK;ASLGS(1)LEGEAEAEASSPK ;;;; 206.62 2.95E-12 3016072400 21030.4 18685.07 18892.03 20331.3 19662.16 27180.4 22448.4 14558.33 24192.1 17315.84 TRUE FALSE FALSE 19365.82165 20300.12419 19592.18525 20247.17447 19427.70158 21542.87865 23078.24169 18997.0978 21538.28716 17917.56415 1.080828928 1.132973434 1.093462542 1.130018249 1.084282519 1.202333 1.288023388 1.060250023 1.202076743 1 14.1290869 -7.352061257 0.23804203 0.966786081 1.215003495 0 0.086470258 1.202011762 0.2735038 0.10966413 0.113263459 4.45E-08 7.352061257 0.248217414 ASLGSLEGEAEAEAS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 4 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 ASLGSLEGEAEAEAS(0.5)S(0.5)PK;ASLGSLEGEAEAEAS(0.885)S(0.115)PK;ASLGSLEGEAEAEAS(0.624)S(0.376)PK;ASLGSLEGEAEAEAS(0.819)S(0.181)PK ;;; 234.82 4.26E-24 2240556900 9048.13 10670.07 9543.28 10184.85 11052.07 11073.3 9824.16 6700.65 10112.58 8251.79 TRUE FALSE FALSE 8331.960963 11592.34331 9896.962352 10142.70779 10920.28128 8776.572758 10099.79949 8743.647339 9003.255274 8538.539088 0.975806385 1.357649498 1.159093172 1.187873907 1.278940246 1.027877564 1.182848657 1.024021469 1.054425726 1 13.05977354 -7.320266206 24.9995095 0.988575162 1.172752059 0.370075884 0.096808825 159.7104764 67871.46922 0.015263185 0.017454117 4.78E-08 7.320266206 0.184176897 ASLGSLEGEAEAEAS(ph)SPKGK ddPTM_HeLa_Curcumin_4h_R1 3 ASLGSLEGEAEAEASSPKGK 20 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 ASLGSLEGEAEAEAS(0.686)S(0.314)PKGK;ASLGSLEGEAEAEAS(0.527)S(0.473)PKGK;ASLGSLEGEAEAEAS(0.558)S(0.442)PKGK ;; 113.78 7.57E-05 403771000 6235.4 4251.43 4374.74 5206 4320.29 6246.6 4990.6 3196.19 6050.6 4971.2 TRUE FALSE FALSE 5741.86151 4618.904665 4536.871713 5184.458951 4268.773363 4950.984746 5130.622804 4170.693618 5386.864318 5143.94883 1.116236125 0.897929746 0.881982279 1.007875296 0.829863108 0.962487169 0.997409378 0.810796094 1.047223543 1 12.32866058 -7.250405973 24.89326639 1.054889282 0.917101782 0.488558777 0.066405154 451.2198854 1018030.123 0.011646397 0.014189876 5.62E-08 7.250405973 -0.1377875 ASLGSLEGEAEAEASS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 ASLGSLEGEAEAEASSPK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 ASLGSLEGEAEAEAS(0.024)S(0.976)PK;ASLGSLEGEAEAEAS(0.242)S(0.758)PK;ASLGSLEGEAEAEAS(0.052)S(0.948)PK;ASLGSLEGEAEAEAS(0.264)S(0.736)PK ;;; 297.55 3.05E-82 860806000 18172.9 14828.3 16408.9 17258.5 18678.2 19115.1 15280.5 10353.86 16765.1 15248.7 TRUE FALSE FALSE 16734.49579 16109.99218 17017.02827 17187.0889 18455.47466 15150.41279 15709.2297 13510.70425 14926.01047 15778.59119 1.060582379 1.021003205 1.078488444 1.08926638 1.169652882 0.960187928 0.995604076 0.856268097 0.94596598 1 13.94568078 -4.220781694 1.509514127 1.043723167 0.775893983 0.462391761 0.060937256 0.804452173 1.542361458 0.008189741 0.329046802 6.01E-05 4.220781694 -0.267829184 ASLGSLEGEAEAEASS(ph)PKGK ddPTM_HeLa_Curcumin_4h_R1 3 ASLGSLEGEAEAEASSPKGK 20 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 ASLGSLEGEAEAEAS(0.157)S(0.843)PKGK;ASLGSLEGEAEAEAS(0.426)S(0.574)PKGK;ASLGSLEGEAEAEAS(0.033)S(0.967)PKGK ;; 142.23 4.52E-05 2658620000 10564.2 8840.6 8737.6 9922.9 8038 13098.2 9275.3 5702.6 13017.1 10550.5 TRUE FALSE FALSE 9728.032423 9604.742071 9061.423142 9881.841669 7942.1521 10381.48567 9535.539955 7441.296488 11589.1567 10917.12909 0.891079728 0.879786434 0.830018869 0.905168528 0.727494567 0.950935506 0.873447577 0.681616607 1.061557173 1 13.4143059 -13.5228787 0.066752417 1.606862266 0.61385044 0.541090627 0.073682898 154.7628641 0.805397778 14.76681183 2.318752427 3.00E-14 13.5228787 -0.993011827 ASLLHSMPTHS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 ASLLHSMPTHSSPR 14 0 E3W994;J3KR49;O75122;E7ERI8;E7EW49;O75122-3;A0A0U1RQI6;H7C4X8 E3W994 CLASP2 CLIP-associating protein 2 1 0 ASLLHSMPT(0.003)HS(0.499)S(0.499)PR;ASLLHSMPT(0.084)HS(0.458)S(0.458)PR ; 104.16 0.0018235 59425000 2623.1 2127.99 2057.23 2059.01 2963.5 4377.2 2493.5 1357.79 2804.5 2441.3 TRUE FALSE FALSE 2415.478867 2311.923973 2133.472754 2050.490362 2928.162198 3469.319379 2563.460899 1771.773921 2496.853367 2526.134993 0.956195482 0.915202069 0.844560073 0.811710525 1.159147158 1.37337054 1.014775895 0.701377371 0.988408527 1 11.30271602 -5.743300272 24.99903976 0.951785372 1.081011358 0.129849896 0.166201742 427.2837893 588872.8184 0.024625572 0.04917389 1.81E-06 5.743300272 0.129225986 ASLLT(ph)DEEDVDMALDQR ddPTM_HeLa_Curcumin_4h_R1 3 ASLLTDEEDVDMALDQR 17 0 A0A3B3ITD8;P52948-6;P52948-2;P52948-5;P52948;H7C3P6 A0A3B3ITD8 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 0 AS(0.455)LLT(0.545)DEEDVDMALDQR;ASLLT(1)DEEDVDMALDQR;AS(0.007)LLT(0.993)DEEDVDMALDQR ;; 307.07 5.29E-95 26112500 3471.82 2687.75 3051.34 3342.08 3148.25 3638.96 2530.19 1638.74 3769.79 3665.9 TRUE FALSE FALSE 3197.021784 2920.067134 3164.425345 3328.251358 3110.709175 2884.198676 2601.180322 2138.384282 3356.253469 3793.289752 0.842809802 0.769798071 0.834216617 0.87740499 0.820055777 0.760342306 0.68573204 0.563728168 0.884787002 1 11.88923386 -2.399687416 0.129559659 1.059805368 1.82E-21 0.719035771 0.059922961 20.15882408 0.251280753 0.238336473 3.750152046 0.003983938 2.399687416 -1.059805368 ASLPQAATFGELSGPLKPGS(ph)PYRPPVPR ddPTM_HeLa_Curcumin_4h_R1 1 ASLPQAATFGELSGPLKPGSPYRPPVPR 28 2 Q14687-2;Q14687-3;Q14687;H0Y613 Q14687-2 GSE1 Genetic suppressor element 1 1 0 ASLPQAAT(0.005)FGELS(0.273)GPLKPGS(0.696)PY(0.026)RPPVPR 59.426 0.00213 18374000 596.13 504.99 479.27 534.29 509.81 782.01 658.75 247.43 664.32 487.83 TRUE FALSE FALSE 548.9456815 548.6390854 497.0321678 532.0792495 503.7308487 619.8123109 677.2327521 322.870268 591.445758 504.7820562 1.087490482 1.086883099 0.98464706 1.054077186 0.997917502 1.22788103 1.341633966 0.639623109 1.171685385 1 8.979516817 ASLQSGQEGAGDS(ph)PGSQFSK ddPTM_HeLa_Curcumin_4h_R1 2 ASLQSGQEGAGDSPGSQFSK 20 0 Q12778 Q12778 FOXO1 Forkhead box protein O1 1 0 ASLQSGQEGAGDS(0.999)PGS(0.001)QFSK;ASLQSGQEGAGDS(0.727)PGS(0.273)QFSK ; 297.29 4.16E-84 12311600 4837.14 3920.63 3908.87 4483.71 4543.6 5922.9 5047.1 1999.6 4939.3 4181.81 TRUE FALSE FALSE 4454.275265 4259.511787 4053.736161 4465.157596 4489.420538 4694.423775 5188.708042 2609.268835 4397.471148 4327.127586 1.029383852 0.984373976 0.93681919 1.031898761 1.037505932 1.084882218 1.199111406 0.603002519 1.01625641 1 12.07919394 -4.246027771 25 1.02380273 0.603002213 0.789788061 0.066702778 1020.440495 1655285.851 0.0091858 0.300295487 5.68E-05 4.246027771 -0.420800517 RDS(ph)S(ph)ESQLASTESDKPTTGR ddPTM_HeLa_Curcumin_4h_R1 1 RDSSESQLASTESDKPTTGR 20 2 A0A087WVF1;Q96B23-2;Q96B23;K7EQH1 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 2 0 RDS(0.929)S(0.777)ES(0.294)QLASTESDKPTTGR 92.671 0.00072416 19496000 1378.9 1063 1001.1 1346.8 1407.6 2895.7 3993.2 4938.3 1348.6 1548.3 TRUE FALSE FALSE 1269.75861 1154.880983 1038.201647 1341.227298 1390.815289 2295.099179 4105.238445 6443.964937 1200.661954 1602.10331 0.79255726 0.720853004 0.648024157 0.837166549 0.868118355 1.432553796 2.56240557 4.02219064 0.749428546 1 10.64575147 -4.458009258 1.391055367 0.8532612 4.702221939 0.989468069 0.106618152 0.075444186 0.166968745 0.019994034 0.364403782 3.48E-05 4.458009258 3.848960739 up ASLSPDASDFEHIT(ph)AETPSRPLSSTSNPFK ddPTM_HeLa_Curcumin_4h_R1 1 ASLSPDASDFEHITAETPSRPLSSTSNPFK 30 1 Q5M775-4;Q5M775;Q5M775-5;Q5M775-3;Q5M775-2 Q5M775-4 SPECC1 Cytospin-B 1 0 ASLSPDAS(0.003)DFEHIT(0.29)AET(0.084)PS(0.084)RPLS(0.084)S(0.084)T(0.084)S(0.29)NPFK 42.321 0.012001 22887000 609.15 616.9 545.81 577.6 684.36 781.38 396.2 152.26 900.52 513.1 TRUE FALSE FALSE 560.9351347 670.2220871 566.0381987 575.2100442 676.199454 619.31298 407.3163057 198.6833731 801.735209 530.9301868 1.056513923 1.262354456 1.066125477 1.083400527 1.273612748 1.166467825 0.767174886 0.374217511 1.510057685 1 9.05237836 -4.451014357 2.834184453 1.075512862 0.363805017 0.670648819 0.168351359 0.100378937 1.35466199 0.015677223 0.131527497 3.54E-05 4.451014357 -0.711707846 TLNAETPKSS(ph)PLPAK ddPTM_HeLa_Curcumin_4h_R1 2 TLNAETPKSSPLPAK 15 1 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 0 TLNAETPKS(0.097)S(0.903)PLPAK;TLNAET(0.004)PKS(0.406)S(0.59)PLPAK ; 97.352 0.0021286 998980000 6928.2 6727.8 6501.6 7474.9 5758.9 6448.7 3140.8 2355.35 7356.7 6851 TRUE FALSE FALSE 6379.825659 7309.321054 6742.555015 7443.970844 5690.228879 5111.166928 3228.922395 3073.485372 6549.688416 7089.07174 0.899952193 1.031068851 0.951119591 1.050062846 0.80267616 0.720992411 0.455478871 0.433552584 0.923913406 1 12.79138101 -5.01939469 1.441672312 0.963292623 0.403558149 0.929401547 0.056745499 0.087274513 0.318979881 0.008866321 0.046397287 9.56E-06 5.01939469 -0.559734474 down ASLT(ph)RTPSRASLTMT(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 ASLTRTPSRASLTMTPSR 18 2 Q9UF83 Q9UF83 Uncharacterized protein DKFZp434B061 2 0 AS(0.06)LT(0.44)RT(0.351)PS(0.074)RAS(0.074)LT(0.001)MT(0.756)PS(0.244)R 62.088 0.0059045 0 755.11 755.5 748.54 605.21 614.02 815.44 515.5 711.96 817.81 724.27 TRUE FALSE FALSE 695.3422467 820.8020536 776.2815509 602.7058014 606.6982125 646.3085521 529.9635426 929.0333265 728.0982891 749.4383286 0.927817834 1.095222945 1.035817787 0.804210004 0.809537209 0.862390576 0.707147636 1.239639462 0.971525289 1 9.549665953 -6.264823757 24.92164726 0.981569685 0.869325005 0.146641485 0.138016913 420.6493841 3097550.425 0.019728566 0.030911391 5.43E-07 6.264823757 -0.11224468 ASLVALPEQT(ph)ASEEETPPPLLTK ddPTM_HeLa_Curcumin_4h_R1 1 ASLVALPEQTASEEETPPPLLTK 23 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 ASLVALPEQT(0.538)AS(0.324)EEET(0.138)PPPLLTK 54.559 0.01221 23857000 2480.8 1574.2 1811.8 2131.3 2040.9 3086.3 2113.8 1953 2729.3 2215.4 TRUE FALSE FALSE 2284.442062 1710.266834 1878.946902 2122.481245 2016.5636 2446.16659 2173.107539 2548.460709 2429.902618 2292.384985 0.996535083 0.746064402 0.819647186 0.925883418 0.879679292 1.067083673 0.947967969 1.11170712 1.059988891 1 11.16263364 -1.613992414 1.176710156 0.956412079 98.86609027 0.197306601 0.098322328 1458.741658 4.039101251 0.015434013 384316.0202 0.024322465 1.613992414 97.90967819 ASLVALPEQTAS(ph)EEETPPPLLTK ddPTM_HeLa_Curcumin_4h_R1 1 ASLVALPEQTASEEETPPPLLTK 23 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 ASLVALPEQT(0.185)AS(0.814)EEETPPPLLTK 104.5 1.21E-05 18259000 4370.6 3479.1 3591.7 3751.8 3599.1 4631.7 3076.9 3489.7 3830.5 3555 TRUE FALSE FALSE 4024.662398 3779.817901 3724.811562 3736.276046 3556.183083 3671.03321 3163.229533 4553.693465 3410.303733 3678.535985 1.094093524 1.027533213 1.012579889 1.015696478 0.966738696 0.997960391 0.859915343 1.23790918 0.927081792 1 11.84491599 -6.836635054 3.444009567 1.045013046 1.004719799 0 0.097679972 0.676551456 16.09089315 0.014104923 0.019129142 1.46E-07 6.836635054 -0.040293247 ASLVRS(ph)LGLT(ph)HPVKPT(ph)GPPCTSSWCGNVS ddPTM_HeLa_Curcumin_4h_R1 1 ASLVRSLGLTHPVKPTGPPCTSSWCGNVS 29 2 A0A2R8Y574 A0A2R8Y574 3 0 AS(0.141)LVRS(0.861)LGLT(0.915)HPVKPT(0.91)GPPCT(0.033)S(0.066)S(0.066)WCGNVS(0.008) 42.791 0.0078817 0 344.1 265.74 349.79 524.37 415.97 514.41 305.07 196.2 496.64 410.85 TRUE FALSE FALSE 316.8641219 288.7093815 362.7535251 522.2002959 411.0098294 407.7155674 313.6294431 256.0204768 442.1598345 425.1270069 0.745339903 0.679113246 0.853282711 1.228339502 0.966793035 0.959044146 0.737731167 0.602221154 1.040065268 1 8.731750101 -9.599765937 1.434400391 0.999016943 0.84223761 0.139949922 0.168910132 0.847190059 3.159038584 0.124848033 0.029672138 2.51E-10 9.599765937 -0.156779333 HLLS(ph)PQLVQYQCGDSGK ddPTM_HeLa_Curcumin_4h_R1 1 HLLSPQLVQYQCGDSGK 17 0 Q9P209 Q9P209 CEP72 Centrosomal protein of 72 kDa 1 0 HLLS(1)PQLVQYQCGDSGK 255.72 1.46E-40 21514000 1442.6 1280.2 1210.7 1357.5 1108.8 896.02 279.91 100.94 1431.5 1341.9 TRUE FALSE FALSE 1328.416688 1390.854784 1255.569607 1351.883025 1095.578284 710.1753518 287.7635213 131.7161413 1274.468031 1388.530925 0.956706591 1.001673609 0.904243171 0.973606709 0.789019722 0.511458073 0.207243149 0.09486007 0.917853545 1 10.43934359 -5.019189213 1.230999389 0.978396732 0.044987527 0.988400395 0.034910836 0.032722484 0.081613274 0.004445564 0.027218724 9.57E-06 5.019189213 -0.933409205 down ASMSEFLES(ph)EDGEVEQQR ddPTM_HeLa_Curcumin_4h_R1 4 ASMSEFLESEDGEVEQQR 18 0 J3QQW9;Q15022 J3QQW9 SUZ12 Polycomb protein SUZ12 1 0 ASMSEFLES(1)EDGEVEQQR;ASMSEFLES(1)EDGEVEQQR;ASMSEFLES(1)EDGEVEQQR;ASMSEFLES(1)EDGEVEQQR ;;; 368.53 8.09E-198 133118000 13192.1 10711.6 11407.5 12190.3 11428.1 13106.1 11211.2 8115.1 13154.4 11900.4 TRUE FALSE FALSE 12147.93136 11637.46297 11830.27199 12139.85977 11291.82737 10387.74712 11525.7561 10589.35663 11711.39523 12313.93801 0.986518801 0.945064281 0.960722067 0.985863316 0.916995632 0.843576369 0.935992701 0.859948834 0.95106823 1 13.58800459 -5.700765426 0.539960636 0.996121486 0.861745198 0.559452478 0.032970897 0.52969892 0.240337016 0.006791867 0.034539686 1.99E-06 5.700765426 -0.134376288 ASNAAVK(ac)LAESK ddPTM_HeLa_Curcumin_4h_R1 2 ASNAAVKLAESK 12 1 F8VXG7;Q99590-2;Q99590;A0A087WTB7 F8VXG7 SCAF11 Protein SCAF11 0 1 ; ASNAAVK(1)LAESK;ASNAAVK(1)LAESK 185.57 8.71E-10 9284300 5694.9 5441.9 4594.3 4116.9 4573 7387.7 3010.6 3034.1 5714.4 4838.7 FALSE TRUE FALSE 5244.142656 5912.273587 4764.5688 4099.865359 4518.469962 5855.407743 3095.069333 3959.183123 5087.544617 5006.844465 1.04739476 1.180838276 0.951611106 0.818852151 0.902458623 1.169480655 0.618167661 0.790754167 1.016117967 1 12.28968592 -6.523115086 24.99905616 1.03638262 0.867985488 0.319523885 0.136234539 8.724561739 922801.5937 0.021273748 0.030253817 3.00E-07 6.523115086 -0.168397132 ASNGDAWVEAHGK ddPTM_HeLa_Curcumin_4h_R1 3 ASNGDAWVEAHGK 13 0 P38646;D6RJI2;A0A3B3ITI4 P38646 HSPA9 "Stress-70 protein, mitochondrial" 0 0 ;; ;; 105.65 0.00093279 4475600 9490.7 8177.6 9262.4 9546.8 10678.5 15736.7 8978.7 8793.5 11125.7 7861.7 FALSE FALSE TRUE 8739.50108 8884.435305 9605.672692 9507.297871 10551.16586 12472.73103 9230.618157 11474.59767 9905.238545 8134.89349 1.074322742 1.092139106 1.180798827 1.168705882 1.297025692 1.533238394 1.134694409 1.410540615 1.217623631 1 12.98990774 -6.336057212 0.782965419 1.027043892 1.353527464 0.443903408 0.114790156 0.277299581 0.336141948 0.018726874 0.042080531 4.61E-07 6.336057212 0.326483573 ASNIFGT(ph)PEENQASWAK ddPTM_HeLa_Curcumin_4h_R1 2 ASNIFGTPEENQASWAK 17 0 Q9UK76-3;J3KSH8 Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 1 0 ASNIFGT(0.794)PEENQAS(0.206)WAK;ASNIFGT(1)PEENQASWAK ; 171.87 0.00014855 53490500 1833.46 3211.5 1968.55 3005.8 1811.48 3418.5 2357.9 1019.98 2736.5 2397 TRUE FALSE FALSE 1688.339706 3489.08775 2041.506195 2993.362796 1789.879284 2709.464566 2424.056328 1330.967207 2436.312796 2480.295572 0.680701012 1.406722566 0.823089884 1.206857292 0.721639511 1.09239584 0.977325588 0.53661637 0.982267123 1 11.27629634 -2.958260636 10.03444033 0.90274926 0.631933463 0 0.250256691 0 0 0.032031532 0 0.001100878 2.958260636 -0.270815797 ASNIFGTPEENQAS(ph)WAK ddPTM_HeLa_Curcumin_4h_R1 1 ASNIFGTPEENQASWAK 17 0 Q9UK76-3;J3KSH8 Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 1 0 ASNIFGT(0.102)PEENQAS(0.898)WAK 159.4 0.00015163 56541000 1570.8 3188.7 1576.5 2980.9 1535.3 2539.8 1929.2 439.79 2219.8 1713 TRUE FALSE FALSE 1446.469522 3464.317019 1634.926477 2968.565826 1516.99255 2013.016851 1983.32816 573.8799465 1976.293494 1772.526622 0.816049533 1.954451333 0.922370618 1.674765156 0.855836257 1.135676511 1.118927149 0.323763795 1.114958426 1 10.79159158 -4.2581743 23.85763673 1.05363455 0.323763269 0.280743624 0.364377067 177.6578934 1298003.877 0.050288075 0.478994456 5.52E-05 4.2581743 -0.729871281 ASNTST(ph)PTKGNTETSASASQTNHVK ddPTM_HeLa_Curcumin_4h_R1 2 ASNTSTPTKGNTETSASASQTNHVK 25 1 Q14004-2;Q14004;A0A2R8Y7W5;A0A2R8Y4Z0;A0A2R8Y7Y0;A0A2R8YCQ1;A0A2R8YD28 Q14004-2 CDK13 Cyclin-dependent kinase 13 1 0 AS(0.031)NT(0.084)S(0.207)T(0.515)PT(0.145)KGNT(0.016)ET(0.001)SASASQTNHVK;AS(0.003)NT(0.013)S(0.124)T(0.35)PT(0.35)KGNT(0.092)ET(0.034)S(0.034)AS(0.001)ASQTNHVK ; 65.064 0.00059253 18274200 3932.8 3349.1 2904.8 2729.8 5184 8156.2 4385.8 2354.2 5256.1 3080.4 TRUE FALSE FALSE 3621.51473 3638.581281 3012.454443 2718.504811 5122.184186 6464.512181 4508.853744 3071.984743 4679.51898 3187.443671 1.136181562 1.141535869 0.945100449 0.852879326 1.606988143 2.028118094 1.414567349 0.963776951 1.46811033 1 11.63818413 -5.752383737 24.99975019 1.049092734 1.534502735 0.321579739 0.288522627 138.4424758 382192.7292 0.037696825 0.074532958 1.77E-06 5.752383737 0.485410001 ASPDQNASTHT(ph)PQSSVK ddPTM_HeLa_Curcumin_4h_R1 1 ASPDQNASTHTPQSSVK 17 0 Q14677-2;Q14677;Q14677-3;H0YD52 Q14677-2 CLINT1 Clathrin interactor 1 1 0 ASPDQNAST(0.002)HT(0.953)PQS(0.023)S(0.023)VK 115.02 0.0008115 5561400 1454.2 1398.5 1101.8 894.69 2143.8 4443.7 2166.8 1126.6 1935.5 999.15 TRUE FALSE FALSE 1339.098536 1519.380108 1142.633677 890.9880098 2118.236585 3522.026529 2227.594576 1470.095154 1723.180492 1033.870388 1.295228639 1.469604049 1.10520012 0.861798558 2.048841527 3.406642234 2.154616867 1.421933707 1.666727776 1 10.01383962 -5.637033297 5.298510042 1.15187447 2.372543914 0.498517439 0.503252699 0.10926612 4.658042682 0.068716061 0.139269582 2.31E-06 5.637033297 1.220669444 ASPEAAS(ph)TPRDPIDVDLPEEAER ddPTM_HeLa_Curcumin_4h_R1 2 ASPEAASTPRDPIDVDLPEEAER 23 1 P29590;P29590-5;P29590-4;P29590-9;P29590-3;P29590-8;H3BVD2;H3BT29;P29590-2 P29590;P29590-2 PML Protein PML 1 0 AS(0.002)PEAAS(0.872)T(0.126)PRDPIDVDLPEEAER;ASPEAAS(0.892)T(0.108)PRDPIDVDLPEEAER ; 118.54 2.07E-06 19137400 1367.84 1395.54 1349.2 1743.66 1670.67 1957.5 1819.83 2428.8 1680.45 1548.23 TRUE FALSE FALSE 1259.574021 1516.164259 1399.202539 1736.445197 1650.748351 1551.492434 1870.889532 3169.329939 1496.108839 1602.030877 0.786235795 0.946401396 0.873392991 1.083902453 1.030409822 0.968453515 1.167823641 1.978320134 0.933882649 1 10.64568624 -1.708393068 0.98873783 0.913994652 200 0.932456917 0.082352684 64.46635207 0.435829473 0.015747158 28631.19518 0.019570726 1.708393068 199.0860053 ASPEPQRENAS(ph)PAPGTTAEEAMSR ddPTM_HeLa_Curcumin_4h_R1 2 ASPEPQRENASPAPGTTAEEAMSR 24 1 P46379-3;P46379;P46379-2;P46379-5;A0A0G2JK23;A0A024RCR6;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 0 AS(0.016)PEPQRENAS(0.967)PAPGT(0.008)T(0.008)AEEAMSR;AS(0.001)PEPQRENAS(0.873)PAPGT(0.084)T(0.042)AEEAMS(0.001)R ; 106.36 1.66E-06 122498000 1994.63 1709.07 1792.06 1813.27 1634.24 2424.1 1648.93 1242.95 2123.7 1981.33 TRUE FALSE FALSE 1836.752931 1856.794395 1858.47532 1805.767169 1614.752755 1921.314335 1695.194538 1621.919733 1890.735423 2050.18107 0.895897908 0.905673368 0.906493259 0.880784237 0.787614703 0.93714373 0.826851132 0.791110481 0.922228505 1 11.00153562 -13.52287875 0.06543785 1.521989823 0.660353495 0.479657886 0.04564186 106.1262613 0.542177566 8.653662117 1.407337955 3.00E-14 13.52287875 -0.861636328 ASPEPQRENASPAPGT(ph)TAEEAMSR ddPTM_HeLa_Curcumin_4h_R1 1 ASPEPQRENASPAPGTTAEEAMSR 24 1 P46379-3;P46379;P46379-2;P46379-5;A0A0G2JK23;A0A024RCR6;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 0 ASPEPQRENAS(0.217)PAPGT(0.389)T(0.389)AEEAMS(0.006)R 58.357 0.0040409 33943000 2437.1 1850.6 1869.2 2419 2268.8 2806.7 2059 1675.3 3010.2 2194.1 TRUE FALSE FALSE 2244.200963 2010.557618 1938.474196 2408.990819 2241.746042 2224.558782 2116.769998 2186.091258 2679.988591 2270.344812 0.988484635 0.885573684 0.853823695 1.06106826 0.987403336 0.979833006 0.932356172 0.962889534 1.180432407 1 11.14869571 -7.492279489 24.32421891 0.994919731 0.95276378 0.156149659 0.079325857 460.4055787 365993.8238 0.009587816 0.010469406 3.22E-08 7.492279489 -0.042155951 ASPEPQRENASPAPGTT(ph)AEEAMSR ddPTM_HeLa_Curcumin_4h_R1 1 ASPEPQRENASPAPGTTAEEAMSR 24 1 P46379-3;P46379;P46379-2;P46379-5;A0A0G2JK23;A0A024RCR6;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 0 ASPEPQRENAS(0.153)PAPGT(0.164)T(0.681)AEEAMS(0.002)R 72.927 0.00043173 37625000 1668.6 1169.9 1235.6 1491.4 1551.7 1982.6 1098.1 1151 1662.3 1313.9 TRUE FALSE FALSE 1536.528549 1271.020943 1281.392423 1485.228982 1533.196991 1571.386411 1128.909731 1501.934601 1479.949849 1359.557927 1.130167769 0.934878108 0.942506676 1.092435234 1.127717297 1.155806884 0.830350593 1.104722772 1.088552256 1 10.40892191 -7.291757814 24.98147203 1.061468101 1.027464153 0.03867749 0.10029353 2698.30773 2223314.35 0.018044966 0.020636565 5.11E-08 7.291757814 -0.034003947 ASPGGVSTSSSDGK(ac)AEK ddPTM_HeLa_Curcumin_4h_R1 1 ASPGGVSTSSSDGKAEK 17 1 P54259 P54259 ATN1 Atrophin-1 0 1 ASPGGVSTSSSDGK(1)AEK 246.96 1.73E-48 1716500 382.07 280.36 245.36 280.27 280.86 372.04 263.19 632.25 238.34 240.36 FALSE TRUE FALSE 351.8287563 304.5930691 254.4532574 279.110317 277.5109279 294.8747102 270.5744031 825.0201145 212.1946983 248.7124921 1.414600261 1.224679414 1.023081934 1.12222074 1.115790066 1.185604743 1.087900333 3.317163957 0.853172659 1 7.958335162 -4.260050682 24.99979284 1.173533538 3.317164654 0.949723382 0.151511024 19.52869943 351524.9056 0.022222208 0.186650018 5.49E-05 4.260050682 2.143631116 DLLVSSGSNNSLPCGS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 DLLVSSGSNNSLPCGSPK 18 0 Q5THK1-3;Q5THK1-2;Q5THK1-4;Q5THK1 Q5THK1-3 PRR14L Protein PRR14L 1 0 DLLVSSGS(0.004)NNS(0.023)LPCGS(0.974)PK 96.604 0.0019104 21648000 2601.8 2600 2727.5 2547.2 2647.7 2350.3 943.68 929.15 3179.1 2688.9 TRUE FALSE FALSE 2395.864785 2824.732415 2828.583549 2536.660361 2616.127907 1862.821287 970.157121 1212.443558 2830.360684 2782.339075 0.861097343 1.015236583 1.016620718 0.911700657 0.940262073 0.669516273 0.348684001 0.435764127 1.017259438 1 11.44208253 -5.017899212 2.521379176 0.944918975 0.387334096 0.939583325 0.05842783 0.053328164 0.66611717 0.009519813 0.033389036 9.60E-06 5.017899212 -0.557584879 down TVSGPGTPEPRPAT(ph)PGASSVEQLRK ddPTM_HeLa_Curcumin_4h_R1 2 TVSGPGTPEPRPATPGASSVEQLRK 25 2 Q9H3U1 Q9H3U1 UNC45A Protein unc-45 homolog A 1 0 TVSGPGT(0.005)PEPRPAT(0.904)PGAS(0.028)S(0.063)VEQLRK;TVSGPGT(0.002)PEPRPAT(0.919)PGAS(0.04)S(0.04)VEQLRK ; 88.872 8.91E-05 83366000 6681.4 4367.2 5238 5593.7 4107.9 4775 3059.4 1704.65 6265.2 5098.1 TRUE FALSE FALSE 6152.56014 4744.681308 5432.124888 5570.554752 4058.915975 3784.611175 3145.23853 2224.389938 5577.923235 5275.258596 1.166304936 0.899421559 1.029736228 1.05597757 0.769425025 0.717426664 0.596224521 0.421664625 1.05737437 1 12.3650261 -5.016406638 0.74217576 1.071475765 0.344720641 0.886450809 0.076106728 0.316957963 0.218924176 0.01530322 0.154906483 9.63E-06 5.016406638 -0.726755124 down ASPSCSS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 2 ASPSCSSPTR 10 0 Q8N5I9;J3KN91;A0A087WT30 Q8N5I9 C12orf45 Uncharacterized protein C12orf45 1 0 ASPSCS(0.003)S(0.772)PT(0.225)R;ASPS(0.016)CS(0.094)S(0.797)PT(0.094)R ; 119.03 0.0047349 402010000 9922.9 9239 10433.4 9417.2 10956.7 10139.8 7536.4 4965.1 7923.1 7663.3 TRUE FALSE FALSE 9137.491994 10037.57799 10820.07098 9378.234122 10826.04851 8036.691181 7747.851101 6478.936133 7053.955753 7929.599105 1.152327107 1.265836754 1.364516773 1.182687044 1.365270598 1.013505358 0.977079799 0.817057212 0.889572809 1 12.95303221 -4.650542275 2.121504507 1.136246329 0.834827509 0.361937703 0.146041532 0.346525575 2.75129542 0.021496052 0.146573604 2.24E-05 4.650542275 -0.30141882 ASPTGTPSRAS(ph)PTGTPSR ddPTM_HeLa_Curcumin_4h_R1 1 ASPTGTPSRASPTGTPSR 18 1 Q9UF83 Q9UF83 Uncharacterized protein DKFZp434B061 1 0 ASPTGTPS(0.003)RAS(0.748)PT(0.219)GT(0.02)PS(0.011)R 75.143 0.0042951 6350800 1218.1 1066.6 1214.7 1239.1 1361.5 1725.4 1494.5 777.83 1959.7 1027.9 TRUE FALSE FALSE 1121.6861 1158.792151 1259.717851 1233.972933 1345.265002 1367.532591 1536.431648 1014.986786 1744.725813 1063.619448 1.054593446 1.089480033 1.184368951 1.160163942 1.264799176 1.285734849 1.444531359 0.954276257 1.640366595 1 10.05476635 -6.736374855 0.911460425 1.018144898 1.252804091 0 0.227907539 0.349916516 0.580773411 0.021494317 0.03465384 1.83E-07 6.736374855 0.234659193 ASPTPLAS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 2 ASPTPLASPGK 11 0 A0A1B0GTL5 A0A1B0GTL5 1 0 ASPT(0.038)PLAS(0.962)PGK;ASPT(0.016)PLAS(0.984)PGK ; 121.21 0.004042 45200000 7611 6300.4 6941.7 6719.7 7600.3 9198.8 7570.3 9980.2 7549.6 6594 TRUE FALSE FALSE 7008.581319 6844.978502 7198.965509 6691.895662 7509.671386 7290.865188 7782.702244 13023.11704 6721.427768 6823.141009 1.027178144 1.003200504 1.055080864 0.980764673 1.100617938 1.068549687 1.140633358 1.908668899 0.985092901 1 12.73622032 -4.20658722 2.516466394 1.022134622 2.180585152 0.980032947 0.037476933 0.059028221 0.409015724 0.005195581 0.153826659 6.21E-05 4.20658722 1.158450529 ASQEPS(ph)PKPGTEVIPAAPR ddPTM_HeLa_Curcumin_4h_R1 2 ASQEPSPKPGTEVIPAAPR 19 1 I3L4I0;I3L1Y9;Q96CP2 I3L4I0 FLYWCH2 FLYWCH family member 2 1 0 AS(0.001)QEPS(0.994)PKPGT(0.005)EVIPAAPR;AS(0.001)QEPS(0.905)PKPGT(0.094)EVIPAAPR ; 119.51 0.0023169 56941800 3477.6 3274.1 2817.4 3025 3297.1 4345.3 3029.1 1342.55 3540.5 3299.1 TRUE FALSE FALSE 3202.34429 3557.098615 2921.815322 3012.483352 3257.784236 3444.035798 3114.088394 1751.887315 3152.116008 3413.743479 0.938074085 1.041993529 0.855897738 0.882457446 0.954314305 1.008873637 0.912220972 0.513186572 0.923360536 1 11.73713894 -4.26559473 3.852603369 0.961698198 0.470936419 0.850271327 0.054571379 0.065296875 1.906077796 0.007655877 0.089632182 5.43E-05 4.26559473 -0.490761779 ASQEPSPKPGT(ph)EVIPAAPR ddPTM_HeLa_Curcumin_4h_R1 1 ASQEPSPKPGTEVIPAAPR 19 1 I3L4I0;I3L1Y9;Q96CP2 I3L4I0 FLYWCH2 FLYWCH family member 2 1 0 ASQEPS(0.083)PKPGT(0.917)EVIPAAPR 126.5 0.001373 24153000 2058.6 1746 1708.8 2000 2067 2514.5 2185 934.06 2096.3 1947.8 TRUE FALSE FALSE 1895.659638 1896.91646 1772.129631 1991.72453 2042.352375 1992.964356 2246.305219 1218.850594 1866.341135 2015.485905 0.940547207 0.941170789 0.879256772 0.988210597 1.013330021 0.988825747 1.114522912 0.604742802 0.926000589 1 10.97691198 -4.247685475 24.95523592 0.975276568 0.604742549 0.77674013 0.059847303 799.9813863 1451470.577 0.008043706 0.217948478 5.65E-05 4.247685475 -0.370534019 S(ph)PSAPAATSSASSSTSSYK ddPTM_HeLa_Curcumin_4h_R1 2 SPSAPAATSSASSSTSSYK 19 0 A0A087X0S7;A0A0C4DH00;A0A087WTU1;A0A0B4J2G4;Q15345-3;Q15345 A0A087X0S7 LRRC41 Leucine-rich repeat-containing protein 41 1 0 S(1)PSAPAATSSASSSTSSYK;S(0.997)PS(0.003)APAATSSASSSTSSYK ; 214.46 3.09E-18 29554300 4022.4 3298.2 3644.1 3304.8 3906.3 2960.6 1533.55 1066.81 3837.6 3165.5 TRUE FALSE FALSE 3704.022796 3583.281712 3779.153552 3291.125613 3859.719924 2346.538187 1576.577286 1392.075458 3416.624881 3275.500889 1.130826375 1.093964506 1.153763555 1.004770178 1.178360212 0.716390643 0.481324029 0.424996208 1.043084706 1 11.67749983 -5.014319998 2.790993665 1.074970498 0.450231129 0.944877935 0.062280659 0.046282418 0.717942552 0.009996676 0.033600649 9.68E-06 5.014319998 -0.624739369 down SSESGNSVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 SSESGNSVKR 10 1 Q9GZU8;H3BU93;H3BNK9 Q9GZU8 FAM192A Protein FAM192A 0 1 SSESGNSVK(1)R 159.34 2.52E-09 15750000 2084.3 2338.8 1905.2 1332.8 1308.1 2585.3 2584 3225.7 2136.2 1803.8 FALSE TRUE FALSE 1919.325456 2540.955451 1975.808388 1327.285227 1292.501762 2049.079638 2656.500086 4209.201081 1901.864205 1866.481916 1.028311841 1.361360873 1.05857355 0.711116039 0.692480195 1.097829891 1.423265912 2.255152351 1.018956674 1 10.86610582 -4.314518493 1.970501839 1.000399021 2.542453432 0.823435843 0.178573222 0.212073228 0.944216964 0.02682827 0.566151624 4.85E-05 4.314518493 1.542054412 up ASQPDLVDT(ph)PTSSKPQPK ddPTM_HeLa_Curcumin_4h_R1 2 ASQPDLVDTPTSSKPQPK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 AS(0.001)QPDLVDT(0.751)PT(0.191)S(0.025)S(0.032)KPQPK;AS(0.003)QPDLVDT(0.934)PT(0.05)S(0.006)S(0.008)KPQPK ; 93.006 0.0019234 34351000 5432.2 3056.6 4478.4 6631.7 5375.1 11263.6 10753.3 3024.9 7386 4623.7 TRUE FALSE FALSE 5002.235638 3320.798884 4644.373444 6604.259783 5311.005443 8927.402393 11055.00866 3947.178085 6575.774279 4784.373231 1.045536248 0.694092773 0.970738113 1.380381392 1.110073397 1.865950243 2.3106493 0.825014666 1.374427529 1 12.22411422 -5.343483522 4.639562961 1.021457641 1.730170966 0.307084178 0.392894882 0.149286411 5.762033036 0.049740181 0.11542478 4.53E-06 5.343483522 0.708713326 ASQS(ph)RPNS(ph)SALETLGGEK ddPTM_HeLa_Curcumin_4h_R1 1 ASQSRPNSSALETLGGEK 18 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 2 0 AS(0.087)QS(0.913)RPNS(0.889)S(0.055)ALET(0.055)LGGEK 69.07 0.011038 64971000 8950.7 7196.6 7591.9 7907.8 8555.1 10397 8693.6 2812.3 9035.5 9032.7 TRUE FALSE FALSE 8242.24265 7818.642037 7873.262493 7875.079619 8453.08602 8240.545002 8937.519018 3669.757324 8044.328256 9346.585653 0.881845302 0.836523874 0.842367768 0.842562184 0.904403633 0.881663669 0.956233576 0.392630792 0.860670255 1 13.19022372 -4.258775522 24.98033786 0.916200015 0.392630603 0.872873653 0.056073939 70.71499945 663091.738 0.009723202 0.088809251 5.51E-05 4.258775522 -0.523569412 ASQS(ph)RPNSSALETLGGEK ddPTM_HeLa_Curcumin_4h_R1 1 ASQSRPNSSALETLGGEK 18 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 0 AS(0.005)QS(0.921)RPNS(0.007)S(0.007)ALET(0.06)LGGEK 105.01 0.0017809 0 726.34 601.43 881.73 825.02 811.38 1015.5 580.09 347.08 1023.5 728.87 TRUE FALSE FALSE 668.8494226 653.4149293 914.4076894 821.6062858 801.7048234 804.873853 596.3657642 452.9030942 911.2246107 754.1981782 0.886835108 0.866370336 1.212423625 1.089377182 1.062989605 1.067191457 0.790728195 0.600509398 1.208203145 1 9.558799855 -4.515890982 3.519095506 0.983453045 0.619477258 0.542655846 0.123658948 0.137738554 3.438302024 0.016122103 0.094562548 3.05E-05 4.515890982 -0.363975787 ASQSRPNS(ph)SALETLGGEK ddPTM_HeLa_Curcumin_4h_R1 1 ASQSRPNSSALETLGGEK 18 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 0 ASQSRPNS(0.791)S(0.208)ALETLGGEK 226.22 1.76E-22 34549000 2342.6 2069.4 2199.8 2388.2 2067.8 2792.7 2034.4 1213.1 2443.2 2075.4 TRUE FALSE FALSE 2157.180738 2248.269715 2281.326523 2378.318261 2043.142836 2213.46254 2091.479789 1582.968606 2175.187073 2147.519996 1.004498558 1.04691445 1.062307465 1.107471998 0.95139642 1.03070637 0.973904687 0.737114723 1.012883269 1 11.06845585 -4.259903313 3.132700161 1.015028509 0.694454039 0.817661381 0.040596273 0.116473022 1.730590694 0.005817319 0.091668674 5.50E-05 4.259903313 -0.32057447 ASRVPS(ph)SDEEVVEEPQS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 ASRVPSSDEEVVEEPQSR 18 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 2 0 ASRVPS(0.739)S(0.264)DEEVVEEPQS(0.997)R 150.65 0.00036191 62765000 2454.9 1613.6 1278.9 1759.4 1258.2 2013.8 1740.1 1483.3 2896.6 1866.5 TRUE FALSE FALSE 2260.592075 1753.072394 1326.297159 1752.120069 1243.196787 1596.11518 1788.922523 1935.551342 2578.850227 1931.360736 1.170466 0.907687705 0.686716435 0.90719462 0.643689583 0.826420021 0.926249814 1.002169768 1.335250416 1 10.91540194 -7.075041321 5.529552587 1.079662016 0.828270558 0.530147377 0.134315015 0.135394244 7.397985715 0.019423025 0.024004242 8.41E-08 7.075041321 -0.251391458 ASS(ph)ASVPAVGASAEGTR ddPTM_HeLa_Curcumin_4h_R1 1 ASSASVPAVGASAEGTR 17 0 A0A2R8YFI4;V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23 A0A2R8YFI4 PANK2 "Pantothenate kinase 2, mitochondrial" 1 0 AS(0.306)S(0.681)AS(0.013)VPAVGASAEGTR 75.998 0.01291 58937000 2490 2065 2241.4 2248.3 2290.8 2947.1 2353.5 1895.5 2654.2 2744.8 TRUE FALSE FALSE 2292.913873 2243.489399 2324.468256 2238.99713 2263.483706 2335.838239 2419.532876 2473.429224 2363.0409 2840.181596 0.807312418 0.789910547 0.818422406 0.788328864 0.796950346 0.822425666 0.851893724 0.870870098 0.832003455 1 11.47176746 -9.152729269 0.800919363 1.005980943 0.816352879 0.091256428 0.056866629 0.191717812 0.212017976 0.022602872 0.005787857 7.04E-10 9.152729269 -0.189628064 ASS(ph)CETYEYPQR ddPTM_HeLa_Curcumin_4h_R1 1 ASSCETYEYPQR 12 0 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 0 AS(0.075)S(0.925)CET(0.001)YEYPQR 187.78 1.46E-05 18173000 1897.8 1230.3 1578.7 1459.5 1744.8 2161.9 2041.6 1930.2 1648.4 1712.9 TRUE FALSE FALSE 1747.587127 1336.64165 1637.208011 1453.460976 1723.9944 1713.49757 2098.881801 2518.709094 1467.574644 1772.423148 0.985987533 0.754132359 0.923711707 0.820041748 0.972676532 0.966754227 1.184187763 1.421054051 0.82800467 1 10.79150736 -4.462837477 1.996380577 0.954417308 1.466423249 0.766021891 0.089118789 0.192327571 1.099541579 0.012809458 0.153689648 3.44E-05 4.462837477 0.512005942 ASS(ph)FSGISVLTR ddPTM_HeLa_Curcumin_4h_R1 2 ASSFSGISVLTR 12 0 H7C1X4;H7BZ47;H7C207;Q15032-2;Q15032-4;Q15032;Q15032-3 H7C1X4 R3HDM1 R3H domain-containing protein 1 1 0 AS(0.038)S(0.961)FS(0.001)GISVLTR;AS(0.001)S(0.892)FS(0.104)GIS(0.003)VLTR ; 165.35 0.00012046 77659000 2341.1 2276.5 1807.11 2187.71 1800.39 4915.7 3481.3 2089.27 2522.3 2398 TRUE FALSE FALSE 2155.799465 2473.270516 1874.083086 2178.657836 1778.921525 3896.128409 3578.975909 2726.278805 2245.61 2481.330322 0.868807932 0.996751821 0.75527352 0.878020075 0.716922495 1.570177245 1.442361735 1.098716596 0.905002442 1 11.27689809 -5.261416273 25 0.909797921 1.377612851 0.718891678 0.140906286 0.859122736 928702.2033 0.020018528 0.04767685 5.48E-06 5.261416273 0.467814931 ASS(ph)HS(ph)SQT(ph)QGGGSVTK ddPTM_HeLa_Curcumin_4h_R1 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 3 0 AS(0.047)S(0.949)HS(0.966)S(0.106)QT(0.91)QGGGS(0.017)VT(0.005)K 90.498 0.017146 14385000 5386.8 5086.3 4634.6 4535.7 6887.4 10660 5528.6 1932.8 7086.7 5351.4 TRUE FALSE FALSE 4960.429096 5525.937108 4806.362353 4516.932475 6805.272253 8448.995837 5683.717637 2522.101822 6309.30674 5537.360752 0.895811076 0.997936988 0.86798794 0.815719379 1.228973975 1.525816398 1.026430802 0.455470022 1.139406844 1 12.4349828 -5.765179044 24.99766121 0.938238699 1.090165762 0.03114068 0.261830734 208.711768 1395138.973 0.037385902 0.069711702 1.72E-06 5.765179044 0.151927063 ASS(ph)HS(ph)SQTQGGGSVTK ddPTM_HeLa_Curcumin_4h_R1 2 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 AS(0.121)S(0.879)HS(0.978)S(0.02)QT(0.002)QGGGSVTK;AS(0.005)S(0.995)HS(0.806)S(0.193)QT(0.001)QGGGSVTK ; 168.5 0.00036909 13304000 3715.9 3061.6 2473 2402.94 4328.9 6543.6 3516.6 1470.61 3746.3 3083 TRUE FALSE FALSE 3421.782594 3326.231062 2564.651555 2392.997271 4277.280695 5186.383598 3615.266332 1918.992219 3335.340263 3190.134021 1.072614057 1.042661857 0.803932229 0.75012437 1.340784013 1.625757277 1.133264718 0.601539687 1.045517286 1 11.63940132 -5.740123824 24.99982737 0.998829161 1.204504166 0.132446866 0.259625384 409.4174683 480180.4303 0.038176386 0.076294099 1.82E-06 5.740123824 0.205675005 ASS(ph)HS(ph)SQTQGGGSVTKK ddPTM_HeLa_Curcumin_4h_R1 2 ASSHSSQTQGGGSVTKK 17 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 AS(0.021)S(0.801)HS(0.778)S(0.348)QT(0.052)QGGGSVTKK;AS(0.043)S(0.891)HS(0.834)S(0.209)QT(0.019)QGGGS(0.002)VT(0.002)KK ; 80.98 0.0036512 17634000 6676.2 5719.9 4890.4 4670.3 7553.8 10663.5 6134.6 2829.47 7600.8 6350.5 TRUE FALSE FALSE 6147.771725 6214.302669 5071.642526 4650.975536 7463.725869 8451.769898 6306.720366 3692.162378 6767.011256 6571.179402 0.935565954 0.945690612 0.771800953 0.707783984 1.135827439 1.286187666 0.959754708 0.561872101 1.02980163 1 12.68193661 -8.681991515 0.946294636 0.994130469 0.924843106 0.036540058 0.195097225 2.232888779 4.017001737 0.084297264 0.040817632 2.08E-09 8.681991515 -0.069287363 ASS(ph)HSS(ph)QTQGGGSVTK ddPTM_HeLa_Curcumin_4h_R1 3 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 AS(0.002)S(0.998)HS(0.295)S(0.696)QT(0.008)QGGGS(0.001)VTK;AS(0.009)S(0.991)HS(0.247)S(0.591)QT(0.16)QGGGS(0.002)VTK;AS(0.009)S(0.986)HS(0.137)S(0.863)QT(0.005)QGGGSVTK ;; 189.8 1.05E-06 651093300 18439.5 14538.7 14262.5 14805.9 23669.5 30763.3 20026 8145.39 20816 14680.5 TRUE FALSE FALSE 16979.99412 15795.36044 14791.0808 14744.63711 23387.25667 24382.64481 20587.87566 10628.88191 18532.53688 15190.64628 1.117792739 1.039808324 0.973696611 0.970639223 1.53958273 1.605109115 1.355299523 0.699699125 1.219996604 1 13.89089563 -5.780520359 24.99925922 1.043462624 1.325677213 0.201069092 0.237765871 248.8118996 325984.6081 0.033801196 0.061338518 1.66E-06 5.780520359 0.282214589 ASS(ph)LDDLR ddPTM_HeLa_Curcumin_4h_R1 2 ASSLDDLR 8 0 Q96P11-5;Q96P11;Q96P11-2;Q96P11-4;Q96P11-3 Q96P11-5 NSUN5 Probable 28S rRNA (cytosine-C(5))-methyltransferase 1 0 AS(0.045)S(0.955)LDDLR;AS(0.1)S(0.9)LDDLR ; 120.99 0.0079659 10772000 10783.5 9582.7 10514.7 10899.2 10935 13372.3 9251.9 7648.4 11985.4 10563.4 TRUE FALSE FALSE 9929.974596 10410.98589 10904.38403 10854.102 10804.60727 10598.73424 9511.483414 9980.361951 10670.63161 10930.47736 0.908466691 0.952473121 0.997612791 0.993012623 0.988484483 0.969649713 0.870180057 0.913076494 0.97622741 1 13.41606879 -4.769188283 24.95298273 0.964065748 0.891628272 0.549778114 0.028593107 124.2141054 399999.741 0.005516698 0.017015476 1.70E-05 4.769188283 -0.072437476 ASS(ph)LEDLVLK ddPTM_HeLa_Curcumin_4h_R1 7 ASSLEDLVLK 10 0 Q15477 Q15477 SKIV2L Helicase SKI2W 1 0 AS(0.053)S(0.947)LEDLVLK;AS(0.009)S(0.991)LEDLVLK;ASS(1)LEDLVLK;AS(0.002)S(0.998)LEDLVLK;ASS(1)LEDLVLK;AS(0.001)S(0.999)LEDLVLK;AS(0.001)S(0.999)LEDLVLK ;;;;;; 218.07 1.47E-10 1602268800 54232.3 47950.5 49277.7 53633.5 45808.9 52721.7 40078.5 38593.41 52042.5 47706.9 TRUE FALSE FALSE 49939.75623 52095.12756 51103.97491 53411.57879 45262.65879 41786.62512 41202.99484 50360.36305 46333.56795 49364.71122 1.011648909 1.055311097 1.035232936 1.081978958 0.916903141 0.846487786 0.834664963 1.020169303 0.938596961 1 15.59119247 -5.619654309 6.68596556 1.016878518 0.891974358 0.483222077 0.058592494 0.118276393 6.97675172 0.007470941 0.015025546 2.40E-06 5.619654309 -0.12490416 ASS(ph)LGEIDESSELR ddPTM_HeLa_Curcumin_4h_R1 5 ASSLGEIDESSELR 14 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 0 AS(0.074)S(0.926)LGEIDESSELR;AS(0.011)S(0.989)LGEIDESSELR;AS(0.009)S(0.991)LGEIDESSELR;AS(0.016)S(0.984)LGEIDESSELR;AS(0.131)S(0.869)LGEIDESSELR ;;;; 222.81 2.02E-14 762535600 5821.05 5620.69 5721.61 6322.38 5663.62 6914.9 5685.37 6466.6 6739.96 6482 TRUE FALSE FALSE 5360.30775 6106.517398 5933.6579 6296.219667 5596.085031 5480.671793 5844.886181 8438.236571 6000.603251 6707.249018 0.799181264 0.910435468 0.884663427 0.938718639 0.83433387 0.817126631 0.871428236 1.258077127 0.894644471 1 12.71150545 -4.259440894 24.88165544 0.892344324 1.258077259 0.795619891 0.056808146 77.92993638 970168.5313 0.010949094 0.095357209 5.50E-05 4.259440894 0.365732935 ASS(ph)LNFLNK ddPTM_HeLa_Curcumin_4h_R1 2 ASSLNFLNK 9 0 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 0 AS(0.004)S(0.996)LNFLNK;AS(0.072)S(0.928)LNFLNK ; 174.57 0.0014036 1372810000 11155.5 8300 10868.2 9567.2 9173.3 11168.9 9354.7 10405.9 10481 8844.8 TRUE FALSE FALSE 10272.5304 9017.415016 11270.98505 9527.613461 9063.914389 8852.344241 9617.167705 13578.61101 9331.260522 9152.156142 1.122416428 0.985277663 1.231511447 1.04102392 0.990358365 0.967241391 1.050808963 1.48365159 1.019569638 1 13.15989595 -4.261206361 24.41335975 1.053626223 1.483651763 0.752329726 0.075308904 5.3207809 556973.1144 0.010790194 0.083933091 5.48E-05 4.261206361 0.430025539 ASS(ph)LNVLNVGGK ddPTM_HeLa_Curcumin_4h_R1 2 ASSLNVLNVGGK 12 0 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 0 AS(0.009)S(0.991)LNVLNVGGK;AS(0.09)S(0.91)LNVLNVGGK ; 198.48 1.23E-06 895730000 11384.1 9273.8 9726 10237.3 9956.1 11392.8 9333.2 9244.3 11158.1 9011.5 TRUE FALSE FALSE 10483.03647 10075.38595 10086.45412 10194.94077 9837.38001 9029.804857 9595.064473 12062.84451 9934.084346 9324.648954 1.124228539 1.08051102 1.081697999 1.093332394 1.054986634 0.96838014 1.029000075 1.293651329 1.065357462 1 13.1868337 -9.484817277 1.218134985 0.99984581 1.087226088 0.052275067 0.08149413 0.743126574 1.967442826 0.054265751 0.01316259 3.27E-10 9.484817277 0.087380278 RSS(ph)SSGDQSSDSLNSPT(ph)LLAL ddPTM_HeLa_Curcumin_4h_R1 1 RSSSSGDQSSDSLNSPTLLAL 21 1 P15408;P15408-3;P15408-2 P15408 FOSL2 Fos-related antigen 2 2 0 RS(0.142)S(0.458)S(0.215)S(0.101)GDQS(0.034)S(0.042)DS(0.009)LNS(0.107)PT(0.893)LLAL 73.796 0.0036926 14674000 1269.1 870 944.01 1058.5 1195.8 1933.8 3121.8 3983.1 1445.3 1606.8 TRUE FALSE FALSE 1168.649396 945.1989234 978.995841 1054.120207 1181.540866 1532.708082 3209.389306 5197.528854 1286.754206 1662.63618 0.702889429 0.568494139 0.588821447 0.634005334 0.710643062 0.921854161 1.930301616 3.126077079 0.773924098 1 10.6992568 -4.454476859 1.886114473 0.784136815 3.403580038 0.969826415 0.134691913 0.088724437 0.433061849 0.026826054 0.353619949 3.51E-05 4.454476859 2.619443223 up ASS(ph)PAES(ph)SPEDSGYMR ddPTM_HeLa_Curcumin_4h_R1 1 ASSPAESSPEDSGYMR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 2 0 AS(0.217)S(0.783)PAES(0.929)S(0.071)PEDS(0.001)GYMR 166.52 0.00044883 25235000 1721.2 1484.1 1511.9 1487.2 1545 1586.6 1478.1 1115.8 1800.3 1293.1 TRUE FALSE FALSE 1584.965204 1612.378991 1567.932344 1481.04636 1526.576884 1257.521275 1519.571508 1456.002283 1602.811594 1338.035129 1.18454678 1.205034873 1.171817025 1.106881522 1.140909421 0.939826801 1.135673851 1.088164468 1.19788454 1 10.38590028 ASS(ph)PAESS(ph)PEDSGYMR ddPTM_HeLa_Curcumin_4h_R1 3 ASSPAESSPEDSGYMR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 2 0 AS(0.028)S(0.97)PAES(0.25)S(0.554)PEDS(0.02)GY(0.178)MR;AS(0.024)S(0.969)PAES(0.09)S(0.91)PEDS(0.007)GYMR;AS(0.002)S(0.998)PAES(0.319)S(0.681)PEDSGYMR ;; 156.72 0.0007086 43823000 9375.2 7369.1 7775.5 8373.5 7797.7 10427.7 8031.5 6486.4 8971 7904.1 TRUE FALSE FALSE 8633.143027 8006.052168 8063.66687 8338.852676 7704.71752 8264.877476 8256.842274 8464.0735 7986.903744 8178.766887 1.05555558 0.978882548 0.985926972 1.01957334 0.942039017 1.010528554 1.009546107 1.034883818 0.976541312 1 12.99766763 -7.247045049 24.95007413 1.026234581 0.996605965 0 0.031268336 1063.31129 1843071.689 0.005112368 0.006246516 5.66E-08 7.247045049 -0.029628616 ASS(ph)PAESSPEDSGYMR ddPTM_HeLa_Curcumin_4h_R1 2 ASSPAESSPEDSGYMR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 AS(0.015)S(0.984)PAESSPEDSGYMR;AS(0.005)S(0.472)PAES(0.327)S(0.196)PEDSGYMR ; 206.67 1.76E-10 33708300 4403.27 3542.55 3342.82 3757.25 3907.74 4906.9 3567.74 2918.52 4324.33 3562.58 TRUE FALSE FALSE 4054.746533 3848.752237 3466.70785 3741.703495 3861.142753 3889.153628 3667.841182 3808.363313 3849.961818 3686.37939 1.099926542 1.0440467 0.940409948 1.015007708 1.047407861 1.05500634 0.994971161 1.033090442 1.044374822 1 11.84798884 -6.967260309 24.99554635 1.048492806 1.014772097 0.156445243 0.037356727 345.1774769 263529.6437 0.00768019 0.010093737 1.08E-07 6.967260309 -0.033720709 ASS(ph)PAQCVT(ph)PVQTVV ddPTM_HeLa_Curcumin_4h_R1 1 ASSPAQCVTPVQTVV 15 0 Q13614;Q13614-2 Q13614 MTMR2 Myotubularin-related protein 2 2 0 AS(0.149)S(0.851)PAQCVT(1)PVQTVV 108.25 0.010869 10580000 1338 1246.3 1371.7 1346 1244.2 1589.3 1540.6 843.86 1537.4 1342.3 TRUE FALSE FALSE 1232.095888 1354.024619 1422.536409 1340.430609 1229.363728 1259.661265 1583.82509 1101.149029 1368.751066 1388.944825 0.887073313 0.974858464 1.024184966 0.965071171 0.885106237 0.906919585 1.14030814 0.792795372 0.985461079 1 10.43977358 -4.881209581 19.43328855 0.947954405 0.980754952 0 0.090046031 6.825933797 1111.171757 0.011898186 0.035695106 1.31E-05 4.881209581 0.032800547 SCT(ph)PSPDQISHR ddPTM_HeLa_Curcumin_4h_R1 2 SCTPSPDQISHR 12 0 Q7Z2W4-2;Q7Z2W4;C9J6P4;Q7Z2W4-3 Q7Z2W4-2 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 0 S(0.153)CT(0.836)PS(0.012)PDQISHR;S(0.016)CT(0.574)PS(0.411)PDQISHR ; 144.4 0.00087576 55654000 2984.7 3486.5 2761.1 3339.4 2445.9 2453.6 1089.24 600.4 3407.7 2999.6 TRUE FALSE FALSE 2748.457846 3787.857524 2863.428795 3325.582448 2416.73424 1944.695702 1119.801143 783.4591961 3033.883836 3103.835877 0.885503601 1.220379451 0.922545169 1.07144275 0.778628232 0.626545919 0.360779754 0.252416438 0.977462713 1 11.59983656 -5.010417655 1.366776306 0.973264032 0.237398721 0.890240845 0.097528685 0.123355993 0.395920336 0.015212931 0.084923663 9.76E-06 5.010417655 -0.73586531 down ASS(ph)PEKAEEDR ddPTM_HeLa_Curcumin_4h_R1 2 ASSPEKAEEDR 11 1 Q8N3D4;H0YDZ9 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 0 AS(0.181)S(0.819)PEKAEEDR;AS(0.334)S(0.666)PEKAEEDR ; 142.76 0.011227 123258000 7664.1 6656.7 7451.5 7493 7232.9 8972.9 6771.3 6125 8513 7400.4 TRUE FALSE FALSE 7057.478398 7232.075486 7727.659145 7461.995951 7146.652391 7111.819395 6961.284454 7992.484304 7579.145198 7657.563349 0.921635 0.944435607 1.009153799 0.974460884 0.933280218 0.928731382 0.909073048 1.043737275 0.989759386 1 12.90266968 -5.775138968 24.9291383 0.96514938 0.948733582 0.023794655 0.041717416 796.9779593 1450261.064 0.006689103 0.012170075 1.68E-06 5.775138968 -0.016415798 HPEPVPEEGS(ph)EDELPPQVHKV ddPTM_HeLa_Curcumin_4h_R1 4 HPEPVPEEGSEDELPPQVHKV 21 1 Q7Z3C6;H7C152;Q7Z3C6-2 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 0 HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV;HPEPVPEEGS(1)EDELPPQVHKV ;;; 98.077 0.00021412 82303000 12464.1 10142.5 11711.2 12886.7 10318.5 8807.2 3592.46 1542.77 12144.3 12587.2 TRUE FALSE FALSE 11477.55333 11019.17251 12145.22737 12833.37825 10195.45863 6980.487442 3693.254759 2013.153471 10812.10067 13024.60426 0.881220888 0.846027433 0.932483408 0.985318094 0.782784522 0.535946222 0.283559844 0.154565423 0.83012892 1 13.66895192 -5.005639348 1.35560628 0.937803985 0.137343064 0.956994243 0.058503386 0.069340281 0.217854838 0.009156251 0.051896973 9.87E-06 5.005639348 -0.80046092 down ASS(ph)PGYIDSPTYSR ddPTM_HeLa_Curcumin_4h_R1 4 ASSPGYIDSPTYSR 14 0 A0A0C4DGA7;O94929-2;O94929-3;O94929 A0A0C4DGA7 ABLIM3 Actin-binding LIM protein 3 1 0 AS(0.076)S(0.924)PGYIDSPTYSR;AS(0.006)S(0.994)PGYIDSPTYSR;ASS(0.998)PGYIDS(0.001)PT(0.001)YSR;AS(0.103)S(0.897)PGYIDSPTYSR ;;; 237.59 1.80E-28 314746000 11245.9 8161.4 9791.3 9238.2 9410.2 10210.4 7636.8 4427.26 9984.7 8513.4 TRUE FALSE FALSE 10355.77515 8866.83505 10154.17419 9199.974776 9297.989511 8092.647945 7851.068055 5777.111193 8889.40339 8809.240016 1.175558292 1.006538025 1.152673122 1.044355104 1.05548146 0.918654496 0.89123103 0.655801316 1.009099919 1 13.10480185 -3.992394636 0.785294508 1.083483989 0.245709041 0.808214453 0.061216816 1.237521208 0.412742291 0.011673966 0.997619421 0.000101767 3.992394636 -0.837774947 ASS(ph)PHGLGSPLVAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 ASSPHGLGSPLVASPR 16 0 Q8IZW8 Q8IZW8 TNS4 Tensin-4 2 0 AS(0.357)S(0.507)PHGLGS(0.154)PLVAS(0.983)PR 102.84 0.0051827 5305600 1280.6 813.41 846.27 802.74 1423.2 1284.9 580.32 338.8 1558.6 551.4 TRUE FALSE FALSE 1179.239159 883.7175359 877.6335107 799.4184746 1406.22927 1018.397256 596.6022173 442.0985604 1387.625479 570.561109 2.066806062 1.548856945 1.538193713 1.401109298 2.464642695 1.78490479 1.045641226 0.774848747 2.432036565 1 9.156237602 -4.617880572 4.709848167 1.594924705 0.83531395 0.312548334 0.460583289 0.207037785 7.650269264 0.067675636 0.278002728 2.41E-05 4.617880572 -0.759610755 ASS(ph)PIKQSHEPVPDTSVEK ddPTM_HeLa_Curcumin_4h_R1 1 ASSPIKQSHEPVPDTSVEK 19 1 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 0 AS(0.17)S(0.821)PIKQS(0.008)HEPVPDTSVEK 62.064 0.0084727 5686600 2050.6 1992.5 1800.3 1922.5 1584.8 2178.2 1485 1096 2352 2093.9 TRUE FALSE FALSE 1888.292846 2164.722822 1867.020702 1914.545204 1565.902295 1726.416767 1526.665103 1430.165355 2093.991484 2166.662869 0.871521303 0.999104592 0.861703373 0.883637797 0.722725403 0.796809135 0.704615898 0.660077474 0.966459302 1 11.08125897 -2.571375852 0.210776195 0.993037871 1.20E-19 0.819974739 0.049508125 8.635537717 0.180656319 0.048500528 2.530520072 0.002683021 2.571375852 -0.993037871 ASS(ph)PPDRIDIFGR ddPTM_HeLa_Curcumin_4h_R1 2 ASSPPDRIDIFGR 13 1 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 1 0 AS(0.156)S(0.844)PPDRIDIFGR;AS(0.142)S(0.858)PPDRIDIFGR ; 91.093 0.0050754 1785410000 6272 4661.4 5155.7 5931.1 5158.2 6787.5 5174.9 5967.2 6634.6 6055.7 TRUE FALSE FALSE 5775.564582 5064.310645 5346.774777 5906.55868 5096.691834 5379.695989 5320.093766 7786.57181 5906.800979 6266.135124 0.921710826 0.80820323 0.853281117 0.942615913 0.813370879 0.858534947 0.849023148 1.242643457 0.942654581 1 12.61336017 -8.554008702 1.032816506 0.99022341 0.90151762 0.027965548 0.120168472 0.86147479 1.867137176 0.040206606 0.02272316 2.79E-09 8.554008702 -0.08870579 ASS(ph)PSASSSSSFR ddPTM_HeLa_Curcumin_4h_R1 1 ASSPSASSSSSFR 13 0 A0A0J9YYE2;Q8IXZ2 A0A0J9YYE2 ZC3H3 Zinc finger CCCH domain-containing protein 3 1 0 AS(0.037)S(0.93)PS(0.014)AS(0.003)S(0.004)S(0.007)S(0.004)SFR 85.536 0.016759 21839000 3522.5 3261.3 3645.6 3849.8 3768 4826.3 3730.7 3895.4 3812.3 3513.4 TRUE FALSE FALSE 3243.690408 3543.19224 3780.709143 3833.870548 3723.069061 3825.270976 3835.373401 5083.089528 3394.100228 3635.490388 0.892229125 0.974611912 1.03994475 1.054567648 1.02408992 1.052202198 1.054981032 1.398185385 0.933601761 1 11.82793427 -1 0.702804392 0.963241031 53.33235242 0.84187032 0.051558613 87.43567873 0.428321361 0.01028493 7208.907049 0.1 1 52.36911139 ASS(ph)PSPLTIGTPESQR ddPTM_HeLa_Curcumin_4h_R1 2 ASSPSPLTIGTPESQR 16 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 0 AS(0.001)S(0.782)PS(0.216)PLT(0.001)IGTPESQR;AS(0.004)S(0.8)PS(0.195)PLTIGTPESQR ; 280.5 1.87E-65 44223200 3445.5 2806.78 3522.3 3674.3 3538.2 3757.1 2167.23 1329.6 3557.3 3148.68 TRUE FALSE FALSE 3172.785039 3049.385556 3652.839537 3659.09672 3496.009276 2977.835109 2228.036641 1734.988919 3167.07309 3258.096396 0.973815582 0.935940864 1.1211576 1.123078103 1.073022051 0.913980051 0.683846139 0.532516141 0.972062427 1 11.66981357 -4.70258746 2.274564175 1.009019869 0.54336442 0.87730964 0.062820379 0.088831534 0.852634285 0.009954054 0.057255787 1.98E-05 4.70258746 -0.465655449 ASS(ph)S(ph)T(ph)MSLKK ddPTM_HeLa_Curcumin_4h_R1 1 ASSSTMSLKK 10 1 G3V112;A0A087WV61;Q8NE09-3;Q8NE09 G3V112 RGS22 Regulator of G-protein signaling 22 3 0 AS(0.119)S(0.888)S(0.912)T(0.912)MS(0.169)LKK 40.045 0.0096937 0 407 349.38 349.45 418.57 449.21 565.2 280.91 327.03 332.57 455.58 TRUE FALSE FALSE 374.7855205 379.5788504 362.4009244 416.8380682 443.8534641 447.9711489 288.7915786 426.7399415 296.087903 471.4113711 0.795028596 0.805196636 0.768757282 0.884234225 0.941541701 0.950276502 0.612610548 0.905238965 0.628088165 1 8.880842749 -9.307683859 0.982568393 1.002137068 0.829849635 0 0.148655779 0.54821327 0.929850356 0.067330411 0.017106034 4.92E-10 9.307683859 -0.172287433 ASS(ph)SGPRSPLDQR ddPTM_HeLa_Curcumin_4h_R1 1 ASSSGPRSPLDQR 13 1 O14646-2;O14646 O14646-2 CHD1 Chromodomain-helicase-DNA-binding protein 1 1 0 AS(0.208)S(0.764)S(0.022)GPRS(0.005)PLDQR 65.528 0.018505 184800000 6117.5 5084.7 5226.7 5540.9 5789.5 6895.7 4778.6 4429.7 6509.8 5228.1 TRUE FALSE FALSE 5633.29342 5524.198811 5420.4061 5517.973224 5720.463994 5465.454089 4912.674655 5780.295138 5795.691227 5409.776086 1.041317299 1.021151102 1.001964964 1.020000299 1.057430826 1.010292109 0.908110535 1.068490645 1.07133662 1 12.40135317 -4.983187542 24.9987889 1.021410974 0.981025781 0.108547004 0.042416544 319.3981108 474914.3041 0.005029057 0.015083793 1.04E-05 4.983187542 -0.040385192 GFEGSCS(ph)QKESEEGNPVR ddPTM_HeLa_Curcumin_4h_R1 1 GFEGSCSQKESEEGNPVR 18 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 GFEGS(0.182)CS(0.805)QKES(0.014)EEGNPVR 57.703 0.014369 18507000 1287.4 1099.9 942.18 737 1521.2 1792.1 2184.9 2369.7 1316.6 1169.1 TRUE FALSE FALSE 1185.500932 1194.970455 977.0980196 733.9504893 1503.060684 1420.398259 2246.202414 3092.210621 1172.172274 1209.726138 0.979974636 0.98780246 0.807701833 0.60670797 1.242480125 1.174148606 1.856785882 2.556124501 0.968956723 1 10.24046477 -4.451580991 1.344209043 0.957001584 2.937766046 0.927010749 0.14704443 0.17261303 0.346679537 0.021886112 0.420472338 3.54E-05 4.451580991 1.980764462 up ASSAS(ph)VPAVGASAEGTRR ddPTM_HeLa_Curcumin_4h_R1 1 ASSASVPAVGASAEGTRR 18 1 A0A2R8YFI4;V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23 A0A2R8YFI4 PANK2 "Pantothenate kinase 2, mitochondrial" 1 0 AS(0.024)S(0.017)AS(0.959)VPAVGASAEGTRR 140.27 0.00014158 14576000 1488.6 1236.8 1380.3 1371.9 1146.1 2040.4 1298.4 1006.3 1770 1508.4 TRUE FALSE FALSE 1370.775739 1343.703481 1431.455132 1366.223441 1132.433506 1617.19804 1334.82961 1313.116238 1575.835428 1560.816788 0.878242565 0.860897635 0.917119257 0.875325952 0.725539035 1.036122915 0.855212232 0.841300688 1.009622296 1 10.60808549 -9.127920396 0.611980309 1.013947595 0.872133065 0.344154525 0.072134636 0.985913786 0.579965893 0.076196519 0.015882816 7.45E-10 9.127920396 -0.14181453 ASSDGEGTMSRPASVDGSPVS(ph)PSTNR ddPTM_HeLa_Curcumin_4h_R1 1 ASSDGEGTMSRPASVDGSPVSPSTNR 26 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 0 ASSDGEGT(0.001)MS(0.002)RPAS(0.002)VDGS(0.04)PVS(0.739)PS(0.155)T(0.062)NR 75.182 0.00013195 11331000 2271.3 2101 2254.5 1929.8 2139.6 2266 1870.3 1012.6 2448.4 2157.5 TRUE FALSE FALSE 2091.524208 2282.601078 2338.053753 1921.814999 2114.086667 1796.006057 1922.775584 1321.337079 2179.816646 2232.472964 0.936864294 1.022454074 1.047293199 0.860845811 0.946970781 0.804491739 0.861276089 0.59187148 0.976413457 1 11.12442699 -3.57534346 0.623730682 0.976690082 1.73E-17 0.801114244 0.056929646 2.180163075 0.317799912 0.009775637 1.857404037 0.000265862 3.57534346 -0.976690082 ASSDGEGTMSRPASVDGSPVSPS(ph)TNR ddPTM_HeLa_Curcumin_4h_R1 1 ASSDGEGTMSRPASVDGSPVSPSTNR 26 1 P35568 P35568 IRS1 Insulin receptor substrate 1 1 0 ASSDGEGT(0.003)MS(0.003)RPAS(0.008)VDGS(0.002)PVS(0.04)PS(0.668)T(0.276)NR 59.855 0.0018712 13219000 977.76 757.68 663.65 710.93 753.39 857.06 574.21 408.11 967.75 937.96 TRUE FALSE FALSE 900.3692643 823.170483 688.2454528 707.98836 744.4063163 679.2960949 590.3207872 532.5408603 861.5902462 970.5540402 0.927685865 0.848144924 0.709126359 0.729468253 0.766991106 0.699905484 0.608230725 0.548697793 0.887730317 1 9.922664734 -5.690007701 0.282249106 1.027884775 0.425326169 0.832327465 0.055405173 0.770171201 0.092155017 0.032946732 0.156365969 2.04E-06 5.690007701 -0.602558606 ASSEDAGPS(ph)PQTR ddPTM_HeLa_Curcumin_4h_R1 1 ASSEDAGPSPQTR 13 0 Q5T5P2;Q5T5P2-3;Q5T5P2-7;Q5T5P2-8;Q5T5P2-6;Q5T5P2-9;Q5T5P2-2;Q5T5P2-10;Q5T5P2-4 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 0 ASSEDAGPS(0.589)PQT(0.411)R 108.66 0.0043354 6360600 1200.6 1412.3 1447.1 1292.5 1092.3 1778.2 1659.5 863.8 1413.8 1124.5 TRUE FALSE FALSE 1105.571243 1534.372919 1500.730799 1287.151977 1079.275036 1409.381276 1706.061104 1127.168644 1258.709677 1163.576291 0.950149338 1.318669803 1.289757114 1.106203338 0.927549868 1.211249564 1.466221954 0.968710562 1.081759474 1 10.18435009 -7.280874956 24.50715983 0.9764594 1.187156482 0.198694813 0.155010576 575.1700903 725255.1549 0.025636992 0.029342603 5.24E-08 7.280874956 0.210697081 ASSEDAGPSPQT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 ASSEDAGPSPQTR 13 0 Q5T5P2;Q5T5P2-3;Q5T5P2-7;Q5T5P2-8;Q5T5P2-6;Q5T5P2-9;Q5T5P2-2;Q5T5P2-10;Q5T5P2-4 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 0 ASSEDAGPS(0.432)PQT(0.568)R 109.55 0.012015 10668000 3371.8 2848.9 3056.7 3417.8 3297.2 5375.9 4729.4 2038.7 3747.6 2696.9 TRUE FALSE FALSE 3104.918472 3095.146222 3169.983991 3403.658049 3257.883043 4260.877741 4862.094235 2660.290245 3336.497656 2790.617074 1.11262792 1.109126096 1.135943738 1.219679361 1.167441808 1.526858622 1.742300755 0.953298204 1.195612858 1 11.44636846 -5.765041287 1.335796429 1.062839271 1.426590966 0.244712185 0.19829283 0.320293461 1.139784444 0.029063285 0.07559811 1.72E-06 5.765041287 0.363751695 ASSEDVASS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 2 ASSEDVASSPER 12 0 M0R2H0;A0A087WWI0;Q9H2I8 M0R2H0 C10orf11 Leucine-rich repeat-containing protein C10orf11 1 0 ASSEDVAS(0.03)S(0.97)PER;ASSEDVAS(0.002)S(0.998)PER ; 190.35 5.70E-06 66666000 14332 11496.2 11517.6 11298.1 12341 14013.5 10160.5 6558.2 14157.1 11784.6 TRUE FALSE FALSE 13197.60708 12489.8803 11944.45239 11251.35146 12193.84164 11106.94214 10445.57628 8557.76499 12604.10155 12194.11397 1.082293236 1.024254844 0.979526058 0.922687083 0.999977666 0.91084454 0.856608058 0.701794735 1.03362176 1 13.57389731 -3.298168829 0.503428417 1.03597076 1.59E-21 0.886825998 0.035037264 2.599576873 0.218516652 0.008792593 1.982507153 0.000503305 3.298168829 -1.03597076 ASSGDQGS(ph)PPCFLR ddPTM_HeLa_Curcumin_4h_R1 1 ASSGDQGSPPCFLR 14 0 A6NN50;O75147-2;O75147-1;O75147-4;O75147 A6NN50 OBSL1 Obscurin-like protein 1 1 0 ASSGDQGS(1)PPCFLR 153.41 0.00043404 9369500 1611.1 1083.9 1391.1 1575.3 1262.7 1909.9 1163.3 959 1704 1743 TRUE FALSE FALSE 1483.579735 1177.587486 1442.65539 1568.781826 1247.643127 1513.765211 1195.939067 1251.394685 1517.075463 1803.56912 0.822579916 0.65292063 0.799889161 0.86982074 0.691763411 0.839316439 0.663095777 0.693843486 0.841151828 1 10.816639 -9.426690402 0.260342957 1.157398569 0.706551742 0.295455783 0.08819613 2.596596762 0.226559971 0.374433156 0.059460737 3.74E-10 9.426690402 -0.450846828 ASSGLQQTNFSSAFS(ph)S(ph)DS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 ASSGLQQTNFSSAFSSDSK 19 0 Q86VR7;Q86VR7-2 Q86VR7 VSIG10L V-set and immunoglobulin domain-containing protein 10-like 3 0 AS(0.003)S(0.004)GLQQT(0.004)NFS(0.008)S(0.197)AFS(0.823)S(0.981)DS(0.981)K 50.188 0.015464 5515900 492.07 515.78 562.87 520.87 542.62 706.93 526.25 268.99 759.61 496.32 TRUE FALSE FALSE 453.1221403 560.3617249 583.7304574 518.714778 536.1496109 560.3047493 541.0151587 351.0038127 676.2826835 513.5670831 0.882303705 1.091116903 1.136619687 1.010023413 1.043971914 1.091005962 1.05344594 0.683462442 1.31683417 1 9.004408926 -3.114370487 13.80678708 0.978652854 1.002304938 0 0.165018921 0 0 0.016806625 0 0.000768475 3.114370487 0.023652084 ASSHS(ph)S(ph)QTQGGGSVTKK ddPTM_HeLa_Curcumin_4h_R1 2 ASSHSSQTQGGGSVTKK 17 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 AS(0.007)S(0.25)HS(0.748)S(0.704)QT(0.291)QGGGSVTKK;AS(0.052)S(0.295)HS(0.848)S(0.805)QTQGGGSVTKK ; 92.773 0.0014515 57621000 8790.4 8149.3 6318.6 6048.2 10042.5 16268.8 9601.2 4099.9 12050.5 8208.7 TRUE FALSE FALSE 8094.630564 8853.689179 6552.772874 6023.174151 9922.749746 12894.46749 9870.583832 5349.940636 10728.5903 8493.951714 0.952987589 1.042352191 0.771463401 0.709113302 1.168213581 1.518076383 1.162072044 0.629852961 1.263085859 1 13.05222019 ASSHS(ph)SQT(ph)QGGGSVTK ddPTM_HeLa_Curcumin_4h_R1 1 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 AS(0.284)S(0.068)HS(0.527)S(0.121)QT(0.829)QGGGS(0.16)VT(0.012)K 99.343 0.0031313 5344300 1986.5 2028.8 1567 1333.3 2627.8 6289.7 1955.7 730.72 2528.7 1910 TRUE FALSE FALSE 1829.266429 2204.160432 1625.074398 1327.783158 2596.465201 4985.14532 2010.571679 953.5131642 2251.307936 1976.372358 0.925567706 1.115255647 0.822251127 0.67182844 1.313753044 2.522371506 1.017304088 0.482456234 1.139111224 1 10.94863907 -5.600841411 8.395735913 0.947335019 1.408607884 0.126216959 0.491056571 0.361571034 34.66958366 0.069690383 0.139659437 2.51E-06 5.600841411 0.461272865 ASSHS(ph)SQTQGGGSVTK ddPTM_HeLa_Curcumin_4h_R1 5 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 AS(0.039)S(0.039)HS(0.753)S(0.169)QTQGGGSVTK;ASS(0.005)HS(0.917)S(0.078)QTQGGGSVTK;ASS(0.013)HS(0.885)S(0.103)QTQGGGSVTK;ASS(0.01)HS(0.495)S(0.495)QTQGGGSVTK;ASSHS(0.544)S(0.456)QTQGGGSVTK ;;;; 290.37 1.52E-79 192139500 20916.7 23899.75 13943.54 12768.88 28866.36 59454.08 19495.45 10753.92 23556.68 16527.2 TRUE FALSE FALSE 19261.12112 25965.53789 14460.29986 12716.04576 28522.14751 47122.63362 20042.43986 14032.7407 20972.57114 17101.51897 1.126281306 1.518317638 0.845556461 0.743562357 1.667813693 2.755464804 1.171968402 0.820555222 1.226357213 1 14.06183685 -5.741143972 24.35888933 1.061650996 1.655346075 0.205570329 0.503236959 201.7019416 242084.0887 0.072385908 0.144615127 1.81E-06 5.741143972 0.59369508 ASSHSSQTQGGGS(ph)VTK ddPTM_HeLa_Curcumin_4h_R1 2 ASSHSSQTQGGGSVTK 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 ASSHSSQT(0.007)QGGGS(0.891)VT(0.102)K;ASSHSSQT(0.002)QGGGS(0.884)VT(0.114)K ; 117.55 0.00051534 5032000 8096.7 13784.6 6851 6799.4 6840.3 16293.5 8315.9 4984.4 7026 7126.1 TRUE FALSE FALSE 7455.837651 14976.0794 7104.904087 6771.265884 6758.73389 12914.04443 8549.221773 6504.120615 6255.265378 7373.731445 1.01113496 2.031004182 0.963542562 0.918295701 0.916596155 1.751358119 1.15941594 0.882066382 0.848317494 1 12.84817916 -7.460863779 24.99999898 1.004906321 1.236363485 0.104254002 0.36476216 446.1008847 179836.3764 0.060607346 0.069299452 3.46E-08 7.460863779 0.231457165 ASSLEDLVLK ddPTM_HeLa_Curcumin_4h_R1 1 ASSLEDLVLK 10 0 Q15477 Q15477 SKIV2L Helicase SKI2W 0 0 138.66 0.00034675 0 2110.3 1620.5 1766.4 1761.2 1640.2 1909.5 1308.4 1182.2 1963.2 1567.8 FALSE FALSE TRUE 1943.267528 1760.568799 1831.864338 1753.912621 1620.641686 1513.448175 1345.110183 1542.647338 1747.841872 1622.280933 1.197861288 1.08524286 1.129190574 1.081139885 0.998989542 0.932913742 0.829147502 0.950912574 1.077397777 1 10.66380796 -5.463544417 1.878712517 1.097859147 0.889918153 0.715920687 0.054298181 0.19245009 1.326414915 0.011656267 0.032049936 3.44E-06 5.463544417 -0.207940994 ASSLGEIDES(ph)SELR ddPTM_HeLa_Curcumin_4h_R1 1 ASSLGEIDESSELR 14 0 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 0 ASSLGEIDES(0.957)S(0.043)ELR 122.63 0.0015704 2759700 1091.3 843.17 1063.5 908.33 1183.7 1157.1 624.43 398.88 1098.8 948.86 TRUE FALSE FALSE 1004.922453 916.0498577 1102.914246 904.5715711 1169.585151 917.1044168 641.9498252 520.4966758 978.2643891 981.8328144 1.023516875 0.932999839 1.123321842 0.921309166 1.191226381 0.934073911 0.653828041 0.530127602 0.996365547 1 9.939333574 -4.739271307 3.005728517 1.018887948 0.554441921 0.832200695 0.077714626 0.062486919 1.118583122 0.009628009 0.042608324 1.82E-05 4.739271307 -0.464446027 ASSLISLLK ddPTM_HeLa_Curcumin_4h_R1 1 ASSLISLLK 9 0 H0Y3P2;D3DQV9;P78344-2;P78344;E9PKF8 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 0 0 107.57 0.00067228 0 0 0 0 98.713 0 120.3 0 0 0 0 FALSE FALSE TRUE 0 0 0 98.30455176 0 95.34842394 0 0 0 0 0 ASSLSESS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 3 ASSLSESSPPK 11 0 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;F8VRN8;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 ASSLS(0.018)ES(0.039)S(0.943)PPK;ASSLSES(0.096)S(0.904)PPK;ASSLSES(0.063)S(0.937)PPK ;; 222.2 1.86E-11 2132066000 24828.4 21707.8 21568.4 24416.4 23162.7 25094.9 20110.3 20281.9 26675.9 22670.8 TRUE FALSE FALSE 22863.20594 23584.1255 22367.74388 24315.37141 22886.49993 19889.93486 20674.54089 26465.75794 23749.62051 23458.60861 0.974619012 1.005350568 0.953498319 1.036522319 0.975611994 0.847873597 0.881319998 1.128189586 1.012405335 1 14.51782983 -5.506932837 24.86728925 0.990004782 0.939746263 0.058620338 0.072066364 1220.382962 1903158.713 0.009567573 0.020821097 3.11E-06 5.506932837 -0.05025852 ASSPAES(ph)SPEDSGYMR ddPTM_HeLa_Curcumin_4h_R1 2 ASSPAESSPEDSGYMR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 ASS(0.015)PAES(0.977)S(0.008)PEDSGYMR;AS(0.001)S(0.086)PAES(0.58)S(0.333)PEDSGYMR ; 219.84 2.08E-15 39059000 4492.6 3800.3 4144.7 4432.2 4000.87 4948 3771.64 3032.63 3912.4 3694.44 TRUE FALSE FALSE 4137.005969 4128.780998 4298.306228 4413.860731 3953.162238 3921.729025 3877.462068 3957.264926 3483.219508 3822.821515 1.082186535 1.08003499 1.124380568 1.154608112 1.034095425 1.025872908 1.014293252 1.035168634 0.911164566 1 11.90042213 -5.54041355 24.99713573 1.058990949 1.025022114 0.05716209 0.063206556 506.3151281 721786.8817 0.00808305 0.016168796 2.88E-06 5.54041355 -0.033968834 ASSPAESS(ph)PEDSGYMR ddPTM_HeLa_Curcumin_4h_R1 1 ASSPAESSPEDSGYMR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 ASSPAES(0.17)S(0.79)PEDS(0.037)GY(0.003)MR 78.191 0.016316 13105000 3604.6 2626.4 2844.5 2863.5 2799 3329.2 2600.7 1629.9 3107.5 2954.4 TRUE FALSE FALSE 3319.292106 2853.414313 2949.919672 2851.651596 2765.623753 2638.686392 2673.668643 2126.849007 2766.615025 3057.06518 1.085777342 0.933383538 0.964951513 0.932806933 0.90466627 0.863143648 0.874586731 0.69571595 0.904990526 1 11.5779316 -3.707993625 0.369595876 1.040668954 0.351227732 0.610197044 0.059931902 2.808719258 0.19574427 0.015414286 0.934704293 0.000195887 3.707993625 -0.689441223 ASSPHGLGSPLVAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 ASSPHGLGSPLVASPR 16 0 Q8IZW8 Q8IZW8 TNS4 Tensin-4 1 0 ASSPHGLGSPLVAS(1)PR 145.94 4.86E-06 0 596.04 642.26 439.35 675.51 794.57 1187.1 404.49 219.95 872.87 420.12 TRUE FALSE FALSE 548.8628051 697.7740925 455.6326975 672.7149186 785.0952717 940.8820786 415.8389008 287.0117425 777.1183448 434.7191387 1.262568763 1.605114729 1.048108208 1.547470214 1.805982764 2.164344734 0.956569113 0.660223388 1.787633153 1 8.763939802 -8.148819897 0.763699563 1.031260995 1.42523167 0 0.475793919 0.932017763 1.182894314 0.159883575 0.10349026 7.10E-09 8.148819897 0.393970675 ASSPPDRIDIFGR ddPTM_HeLa_Curcumin_4h_R1 1 ASSPPDRIDIFGR 13 1 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 0 0 105.36 0.0043484 2427100 1878.4 1550.6 1452.7 1703.7 1465.8 1706.4 1700 1373.9 2112.9 1579.5 FALSE FALSE TRUE 1729.722658 1684.626955 1506.53834 1696.650541 1448.321292 1352.473405 1747.697425 1792.795785 1881.120156 1634.387507 1.058330812 1.030739006 0.921775487 1.038095637 0.886155386 0.827510856 1.069328673 1.096922105 1.150963372 1 10.67453437 -6.79947452 24.27907883 1.028554327 0.970020665 0.154125505 0.087727434 212.8465604 135866.0495 0.013222022 0.017377415 1.59E-07 6.79947452 -0.058533662 NS(ph)GSDGSPS(ph)PLLAR ddPTM_HeLa_Curcumin_4h_R1 1 NSGSDGSPSPLLAR 14 0 H7C1V4;Q9HCH0-2;Q9HCH0 H7C1V4 NCKAP5L Nck-associated protein 5-like 2 0 NS(0.924)GS(0.069)DGS(0.01)PS(0.997)PLLAR 94.569 0.018337 31660000 4978.2 3793.8 4246.5 4364.7 4159.9 3438.2 1705.2 1061.1 4576.2 3463.4 TRUE FALSE FALSE 4584.170217 4121.719167 4403.879026 4346.640028 4110.295909 2725.078563 1753.043323 1384.624505 4074.202309 3583.752892 1.279153545 1.150112547 1.228845615 1.212873811 1.146925034 0.760398009 0.489164118 0.386361601 1.136853581 1 11.80725545 -4.994854942 2.079720019 1.152350114 0.408228457 0.942036359 0.073381161 0.080911236 0.673131062 0.016221907 0.065156354 1.01E-05 4.994854942 -0.744121657 down ASSSKES(ph)PSPSVR ddPTM_HeLa_Curcumin_4h_R1 1 ASSSKESPSPSVR 13 1 H0Y517;H7C1U3;Q5T0F9-3;Q5T0F9-2;Q5T0F9 H0Y517 CC2D1B Coiled-coil and C2 domain-containing protein 1B 1 0 AS(0.017)S(0.105)S(0.198)KES(0.681)PSPSVR 219.95 9.21E-13 12440000 1864.5 1403 1393.2 1395 1630.6 2090.8 1497.8 501.44 1874 1349.3 TRUE FALSE FALSE 1716.922858 1524.269068 1444.833218 1389.22786 1611.15616 1657.144512 1539.824237 654.3267477 1668.426889 1396.188075 1.229721761 1.091736204 1.034841397 0.995014844 1.153967857 1.186906365 1.102877374 0.468652297 1.194987208 1 10.44727758 -4.261488917 9.822505463 1.104949226 0.466934255 0.858491251 0.078092605 0.024364229 70.44548455 0.01326755 0.102876718 5.48E-05 4.261488917 -0.638014971 ASST(ph)PSSETQEEFVDDFR ddPTM_HeLa_Curcumin_4h_R1 1 ASSTPSSETQEEFVDDFR 18 0 F5H1T5;F5H6A0;J3KP58;P30622-2;P30622-1;P30622;F5H367;F5H270 F5H1T5 CLIP1 CAP-Gly domain-containing linker protein 1 1 0 AS(0.016)S(0.1)T(0.856)PS(0.012)S(0.003)ET(0.012)QEEFVDDFR 156.13 0.0001465 12282000 765.53 511.78 501.48 605.88 706.11 1027.1 751.09 574.18 552.84 679.7 TRUE FALSE FALSE 704.9374927 556.0159828 520.0652899 603.3730291 697.6900994 814.0678822 772.1635639 749.2448388 492.1948351 703.3195244 1.002300474 0.790559573 0.73944384 0.857893188 0.991995921 1.157465212 1.097884442 1.065297938 0.699816823 1 9.458036457 -5.416597492 5.365333046 0.951834844 1.104554174 0.320770697 0.123646981 0.239514996 10.01309412 0.016640832 0.037703741 3.83E-06 5.416597492 0.15271933 ASSTPSS(ph)ETQEEFVDDFR ddPTM_HeLa_Curcumin_4h_R1 1 ASSTPSSETQEEFVDDFR 18 0 F5H1T5;F5H6A0;J3KP58;P30622-2;P30622-1;P30622;F5H367;F5H270 F5H1T5 CLIP1 CAP-Gly domain-containing linker protein 1 1 0 ASS(0.004)T(0.001)PS(0.028)S(0.822)ET(0.145)QEEFVDDFR 164.2 1.91E-05 13554000 1435.1 854.73 1138.3 1257 1198.5 1394.4 1003.6 675.93 1423.1 1099.6 TRUE FALSE FALSE 1321.510321 928.6090526 1180.486399 1251.798867 1184.20867 1105.185722 1031.758315 882.0179454 1266.98949 1137.811018 1.161449748 0.816136457 1.037506563 1.100181706 1.040777995 0.971326261 0.906792339 0.775188438 1.11353245 1 10.15204524 -4.196233077 0.907580145 1.056692865 0.59029866 0.461699156 0.088446286 1.634211559 0.92587365 0.015293843 0.773141824 6.36E-05 4.196233077 -0.466394204 T(ph)SPTPPESATTVK ddPTM_HeLa_Curcumin_4h_R1 4 TSPTPPESATTVK 13 0 Q5M775-4;Q5M775;J3KSG2 Q5M775-4 SPECC1 Cytospin-B 1 0 T(0.862)S(0.138)PTPPESATTVK;T(0.864)S(0.133)PT(0.002)PPESATTVK;T(0.878)S(0.121)PT(0.001)PPESATTVK;T(0.999)S(0.001)PTPPESATTVK ;;; 190.34 2.35E-05 713568000 19866.9 16787.1 17675.9 17011.2 15416.2 14980.8 7713 4689.41 20615.3 16645.5 TRUE FALSE FALSE 18294.4139 18238.10212 18330.9844 16940.81216 15232.37188 11873.61321 7929.406022 6119.189522 18353.85317 17223.92989 1.062150974 1.058881582 1.064274212 0.983562536 0.884372613 0.689367252 0.460371476 0.355272552 1.065601944 1 14.07212673 -4.99270299 1.148074769 1.035738242 0.309830836 0.991093117 0.02393871 0.050929379 0.105494578 0.004706994 0.032292984 1.02E-05 4.99270299 -0.725907406 down ASSVSTKES(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 1 ASSVSTKESPAR 12 1 E7ETY2;Q13428-6;Q13428-7;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 ASS(0.004)VS(0.005)T(0.003)KES(0.988)PAR 172.85 0.0013019 86918000 3047.2 2531.9 2438.8 2314.6 2367.8 3116.4 2293.8 1574.8 3055.2 2577.3 TRUE FALSE FALSE 2806.010905 2750.746154 2529.184073 2305.022798 2339.565531 2470.023511 2358.157855 2054.949271 2720.052204 2666.860983 1.052177418 1.031454647 0.948374921 0.864320568 0.877273149 0.926191326 0.884244762 0.770549827 1.019945254 1 11.38092691 -6.511865473 2.694746413 1.025908433 0.86957347 0.793562944 0.03871853 0.097705385 1.428476165 0.006583096 0.010080767 3.08E-07 6.511865473 -0.156334963 AST(ph)PDWVSEGPQPGLR ddPTM_HeLa_Curcumin_4h_R1 3 ASTPDWVSEGPQPGLR 16 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 AS(0.024)T(0.976)PDWVSEGPQPGLR;AS(0.046)T(0.954)PDWVSEGPQPGLR;AS(0.002)T(0.998)PDWVSEGPQPGLR ;; 200.63 1.08E-08 385162000 8769.79 6675.6 7480.13 7524.43 6204.59 5765.92 3717.85 3494.41 7931.08 7212.47 TRUE FALSE FALSE 8075.651868 7252.609118 7757.350198 7493.295902 6130.604317 4570.003197 3822.162865 4559.839523 7061.060367 7463.102796 1.082076998 0.97179542 1.039426953 1.004045651 0.821455162 0.612346275 0.512141259 0.610984419 0.946129319 1 12.86555984 -5.464645521 1.863050226 1.034246824 0.55589851 0.945837565 0.045819124 0.045077246 0.305507478 0.006244676 0.017222279 3.43E-06 5.464645521 -0.478348314 GLLAQGLRPES(ph)PPPAGPLLNGAPAGES(ph)PQPK ddPTM_HeLa_Curcumin_4h_R1 1 GLLAQGLRPESPPPAGPLLNGAPAGESPQPK 31 1 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 2 0 GLLAQGLRPES(1)PPPAGPLLNGAPAGES(1)PQPK 65.234 0.0002432 431770000 2868.2 2181.6 2358 2297.8 1887.9 2242.3 1514.6 872.91 2611.2 2454.9 TRUE FALSE FALSE 2641.178943 2370.167783 2445.389554 2288.292312 1865.388026 1777.221704 1557.0956 1139.056241 2324.757893 2540.207592 1.039749252 0.933060664 0.962673114 0.900828861 0.734344717 0.699636404 0.612979665 0.448410691 0.915184216 1 11.31073069 -4.989584976 0.570275741 1.02219948 0.335488733 0.931294426 0.047757345 0.231936385 0.082502484 0.007307455 0.089971521 1.02E-05 4.989584976 -0.686710747 down AST(ph)PYIEK ddPTM_HeLa_Curcumin_4h_R1 1 ASTPYIEK 8 0 C9J618;C9J5A2;C9J347;C9J7P5;C9IZN7;Q969Z0-2;Q969Z0 C9J618 TBRG4 Protein TBRG4 1 0 AS(0.061)T(0.939)PYIEK 154.85 0.00419 18045000 7335.1 6651 7021.4 7451.3 7308.4 8401.4 5650.2 3425.5 8109.3 6234.7 TRUE FALSE FALSE 6754.519095 7225.882804 7281.619261 7420.468495 7221.252103 6658.854937 5808.729405 4469.919181 7219.730078 6451.355361 1.046992255 1.120056546 1.128696042 1.150218532 1.119338759 1.032163718 0.900389 0.692865132 1.119102836 1 12.65538657 -4.412336089 2.031485602 1.054490882 0.648393849 0.828875252 0.055479453 0.200574752 1.122668383 0.00958098 0.13321482 3.87E-05 4.412336089 -0.406097033 ASTAPGAEAS(ph)PSPCITER ddPTM_HeLa_Curcumin_4h_R1 1 ASTAPGAEASPSPCITER 18 0 Q66PJ3 Q66PJ3 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 0 ASTAPGAEAS(0.994)PS(0.006)PCITER 163.44 3.13E-13 0 2575.4 1886.1 2229.7 2177.7 2356.1 2146.5 1604 1174.4 2796.5 2040.8 TRUE FALSE FALSE 2371.554372 2049.12608 2312.334643 2168.689254 2328.005046 1701.291704 1649.003923 1532.469154 2489.730946 2111.717648 1.123045202 0.970359878 1.095001808 1.026978799 1.102422499 0.805643551 0.780882768 0.725697943 1.179007501 1 11.04420123 -5.187244328 4.724828416 1.055599017 0.763735939 0.834971799 0.061028553 0.059949237 2.510874711 0.007828436 0.020609258 6.50E-06 5.187244328 -0.291863079 ASTAPGAEASPS(ph)PCITER ddPTM_HeLa_Curcumin_4h_R1 1 ASTAPGAEASPSPCITER 18 0 Q66PJ3 Q66PJ3 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 0 ASTAPGAEAS(0.208)PS(0.766)PCIT(0.026)ER 174.35 1.62E-18 0 2596.7 2099 2164.7 2010 2318.6 2281 1883 1487.7 2274.1 2073.4 TRUE FALSE FALSE 2391.168455 2280.428207 2244.925686 2001.683153 2290.952209 1807.894888 1935.831912 1941.292881 2024.63692 2145.450496 1.114529773 1.062913459 1.046365642 0.932989671 1.067818723 0.842664462 0.902296239 0.90484161 0.943688481 1 11.0670649 -5.538693134 1.085945353 1.054666147 0.881224351 0.413524112 0.064770586 0.308815438 0.679072744 0.009893018 0.036103596 2.89E-06 5.538693134 -0.173441796 ASTSDYQVISDRQT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 ASTSDYQVISDRQTPK 16 1 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 0 ASTSDYQVIS(0.331)DRQT(0.669)PK;ASTSDYQVIS(0.018)DRQT(0.982)PK ; 169.72 0.0012849 108057000 7689.6 5890.1 6197.9 6735 7145.8 9904.5 8628.3 5184.8 6734.2 5890.2 TRUE FALSE FALSE 7080.960046 6399.213998 6427.599626 6707.132355 7060.591002 7850.195053 8870.386876 6765.621652 5995.475108 6094.884012 1.161787498 1.049932039 1.054589327 1.100452829 1.158445508 1.287997448 1.455382393 1.110049287 0.983689779 1 12.57338305 -5.446011231 2.461415094 1.075594346 1.302861232 0.544529658 0.091531839 0.171296568 2.025464298 0.013518199 0.034002823 3.58E-06 5.446011231 0.227266887 ASTSSSSSSS(ph)SNQQTEKETNTPK ddPTM_HeLa_Curcumin_4h_R1 1 ASTSSSSSSSSNQQTEKETNTPK 23 1 C9J2P0;P51965-3;P51965 C9J2P0 UBE2E1 Ubiquitin-conjugating enzyme E2 E1 1 0 ASTSSSSS(0.005)S(0.109)S(0.47)S(0.147)NQQT(0.037)EKET(0.044)NT(0.188)PK 116.98 2.00E-06 8393400 1434.2 1316.1 996.71 1266.3 1418.3 1679.3 1344.6 233.74 1252.8 1020.1 TRUE FALSE FALSE 1320.681557 1429.85782 1033.648949 1261.060386 1401.387699 1330.99425 1382.325857 305.00625 1115.370974 1055.548399 1.251180484 1.354611329 0.979253012 1.194696887 1.327639453 1.26095047 1.309580743 0.288955249 1.056674403 1 10.04377702 -4.255657548 24.95857371 1.165309928 0.288954863 0.807056098 0.131958593 231.661464 999988.5303 0.020690419 0.246148184 5.55E-05 4.255657548 -0.876355066 ASTSSSSSSSSNQQTEKETNT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 ASTSSSSSSSSNQQTEKETNTPK 23 1 C9J2P0;P51965-3;P51965 C9J2P0 UBE2E1 Ubiquitin-conjugating enzyme E2 E1 1 0 ASTSSSSS(0.001)S(0.012)S(0.012)S(0.04)NQQT(0.094)EKET(0.106)NT(0.736)PK;ASTSSSSS(0.001)S(0.001)S(0.002)S(0.004)NQQT(0.107)EKET(0.255)NT(0.628)PK;ASTSSSSSS(0.001)S(0.002)S(0.001)NQQT(0.005)EKET(0.053)NT(0.938)PK ;; 80.847 0.00042808 69206000 3749.65 3482.48 3929.84 4141.54 4258.93 5408.75 4408.92 990.78 3779.47 3214.69 TRUE FALSE FALSE 3452.861246 3783.490054 4075.483327 4124.403405 4208.145041 4286.914281 4532.622429 1292.864261 3364.871597 3326.400238 1.038017376 1.137412753 1.225193313 1.239899925 1.265074778 1.288754802 1.362620883 0.388667679 1.011565463 1 11.69974605 -7.281073155 3.11706792 1.016123901 1.159303845 0.030999818 0.259690411 0.582084601 11.26970073 0.04269199 0.050137148 5.24E-08 7.281073155 0.143179944 ASTTS(ph)LSGSDS(ph)ETEGK ddPTM_HeLa_Curcumin_4h_R1 1 ASTTSLSGSDSETEGK 16 0 Q5T7F5;Q8N1G2 Q5T7F5 CMTR1 Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 2 0 AS(0.008)T(0.034)T(0.17)S(0.68)LS(0.041)GS(0.116)DS(0.915)ET(0.036)EGK 86.777 0.005777 0 3032.4 2320.2 2791.4 2636.2 2911.1 2798.3 2112.2 1998 2604.1 2489.2 TRUE FALSE FALSE 2792.38234 2520.747749 2894.85174 2625.292103 2876.387034 2217.901037 2171.462647 2607.181002 2318.436745 2575.699515 1.084125817 0.978665304 1.123908951 1.019254027 1.116740139 0.861086871 0.843057443 1.0122225 0.900119262 1 11.33074858 -5.253351774 24.99743048 1.04522689 0.899215783 0.355149289 0.076421834 350.9190623 1084628.782 0.008458592 0.021148585 5.58E-06 5.253351774 -0.146011107 ASTTSLSGS(ph)DSETEGK ddPTM_HeLa_Curcumin_4h_R1 1 ASTTSLSGSDSETEGK 16 0 Q5T7F5;Q8N1G2 Q5T7F5 CMTR1 Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 1 0 ASTT(0.001)S(0.001)LS(0.013)GS(0.938)DS(0.045)ET(0.001)EGK 220.25 1.92E-15 8183100 5431 4851.4 4634.8 5226.3 4864.3 5642.5 4371.6 4621.6 5085 4411.3 TRUE FALSE FALSE 5001.130619 5270.733399 4806.569765 5204.674955 4806.296399 4472.181896 4494.25533 6030.704565 4527.188222 4564.592347 1.095635763 1.154699697 1.053011835 1.140227771 1.052951947 0.979754939 0.984590734 1.321192367 0.991805594 1 12.15627031 -9.124187767 0.911592844 1.000571873 1.089884044 0.154182258 0.093041613 0.987354763 1.496885424 0.056860457 0.017057288 7.51E-10 9.124187767 0.089312171 ERS(ph)ESLDPDSSMDTTLILK ddPTM_HeLa_Curcumin_4h_R1 1 ERSESLDPDSSMDTTLILK 19 1 H0Y2V6;Q5SW79;Q5SW79-3;Q5SW79-2 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 0 ERS(0.437)ES(0.437)LDPDS(0.121)S(0.005)MDTTLILK 85.013 0.0075151 3753800 1598.5 1491.8 1672.6 1384.2 1401.9 1251.4 720.44 407.39 1755.7 1412.8 TRUE FALSE FALSE 1471.977038 1620.744545 1734.588027 1378.472547 1385.183258 991.8455338 740.6536074 531.6013356 1563.104103 1461.894695 1.006896764 1.108660255 1.186534183 0.942935597 0.947526017 0.678465786 0.506639507 0.363638597 1.069231668 1 10.51362368 -4.986399443 1.358780602 1.025060655 0.36009016 0.935238516 0.065758709 0.097502953 0.306125765 0.010536785 0.061339975 1.03E-05 4.986399443 -0.664970495 down SAS(ph)PTVPR ddPTM_HeLa_Curcumin_4h_R1 3 SASPTVPR 8 0 K7EQ87;K7EKI0;Q92817 K7EQ87 EVPL Envoplakin 1 0 S(0.012)AS(0.974)PT(0.014)VPR;S(0.118)AS(0.84)PT(0.042)VPR;S(0.013)AS(0.787)PT(0.2)VPR ;; 117.53 0.0090474 535130000 19105.4 16714.5 16157.4 17472 16100.7 13264.1 7876.3 3688.6 19952.3 17093.6 TRUE FALSE FALSE 17593.18743 18159.2269 16756.20746 17399.70549 15908.70967 10512.97614 8097.28778 4813.23716 17763.58261 17687.60133 0.994662142 1.026664191 0.947341991 0.983723297 0.899427196 0.594369804 0.457794566 0.272124924 1.004295737 1 14.11045079 -4.984126297 1.217043286 0.998928788 0.261157906 0.986670564 0.029909779 0.04077226 0.097409503 0.004148387 0.027136558 1.04E-05 4.984126297 -0.737770881 down ASVEDADTQSK ddPTM_HeLa_Curcumin_4h_R1 1 ASVEDADTQSK 11 0 H0YI98;F8W1I6;Q13561;Q13561-3;Q13561-2 H0YI98 DCTN2 Dynactin subunit 2 0 0 163.66 3.71E-25 0 907.61 793.16 843.97 878.13 723.24 1243.7 800.65 796.08 1068.4 842.74 FALSE FALSE TRUE 835.7717108 861.7172161 875.2482706 874.4965307 714.6158354 985.7426006 823.1140842 1038.801127 951.199193 872.0251523 0.958426152 0.988179313 1.00369613 1.002834068 0.819489935 1.130406156 0.943910943 1.191251336 1.090793299 1 9.768225938 -2.067553188 1.540657107 0.979388142 199.9622511 0.324606503 0.081265882 931.6131916 2.923681544 0.009424021 654435.9208 0.008559469 2.067553188 198.9828629 ASVGMYLIS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 ASVGMYLISK 10 0 F8WEJ5;P08243-3;P08243-2;P08243 F8WEJ5 ASNS Asparagine synthetase [glutamine-hydrolyzing] 1 0 ASVGMYLIS(1)K 116.37 0.005195 17633000 2260.2 1711.7 1877.5 2041.7 1890.8 2224.3 1614.6 2060.5 1910.6 1794.3 TRUE FALSE FALSE 2081.302785 1859.651721 1947.081802 2033.251986 1868.253445 1762.955107 1659.901331 2688.736965 1701.01196 1856.651791 1.120997914 1.001615774 1.048705961 1.095117564 1.006248696 0.949534595 0.894029423 1.448164366 0.916171771 1 10.85848755 -4.24873404 24.99740111 1.037749019 1.448164624 0.745025887 0.075685272 829.9731019 1632921.048 0.010338011 0.250776292 5.64E-05 4.24873404 0.410415605 ASVITQVFHVPLEER ddPTM_HeLa_Curcumin_4h_R1 1 ASVITQVFHVPLEER 15 0 Q00341;Q00341-2;A0A024R4E5;C9JHZ8;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JK79;C9JHS7;C9JT62 Q00341 HDLBP Vigilin 0 0 102.64 0.0024408 5950500 1536.1 1167.6 1312.3 1032.9 1202.9 1775.1 1419.2 1298.1 1428.6 1463.5 FALSE FALSE TRUE 1414.516064 1268.522141 1360.934992 1028.626133 1188.556203 1406.92425 1459.018932 1693.884714 1271.886154 1514.356516 0.934070709 0.837664135 0.898688636 0.67924965 0.784858909 0.929057481 0.963458021 1.118550814 0.839885549 1 10.56448918 -4.274749955 2.512314136 0.918175073 1.158532025 0.287849065 0.097419045 0.603556324 4.835515866 0.015956662 0.304437751 5.31E-05 4.274749955 0.240356952 ASVLDTS(ph)MS(ph)AGSGSPSK ddPTM_HeLa_Curcumin_4h_R1 1 ASVLDTSMSAGSGSPSK 17 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 2 0 ASVLDT(0.136)S(0.863)MS(0.941)AGS(0.027)GS(0.03)PS(0.003)K 102.63 0.0020307 6162200 2123.1 2078.2 2389.5 2536.9 2797.9 3797.8 2802.2 1320.5 2066 3321.9 TRUE FALSE FALSE 1955.054395 2257.830348 2478.056972 2526.40298 2764.53687 3010.09347 2880.82219 1723.114371 1839.364969 3437.335778 0.568770269 0.656854754 0.720923742 0.734988707 0.80426733 0.875705391 0.838097403 0.501293584 0.535113555 1 11.74707507 -9.512824662 1.278158881 0.999252766 0.706621679 0 0.179703932 0.328521013 0.964636277 0.082856651 0.020189965 3.07E-10 9.512824662 -0.292631087 ASVLDTSMS(ph)AGSGSPSK ddPTM_HeLa_Curcumin_4h_R1 4 ASVLDTSMSAGSGSPSK 17 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 ASVLDT(0.028)S(0.141)MS(0.733)AGS(0.064)GS(0.034)PSK;ASVLDTS(0.001)MS(0.997)AGS(0.002)GSPSK;ASVLDT(0.001)S(0.004)MS(0.995)AGS(0.001)GSPSK;ASVLDT(0.024)S(0.141)MS(0.833)AGS(0.001)GSPSK ;;; 165.24 0.00012922 978732000 23780.6 19611.9 21606 20769.2 23087.1 26809 24644.4 17068.4 21336.1 16723.9 TRUE FALSE FALSE 21898.34042 21307.06525 22406.73737 20683.26255 22811.80141 21248.5112 25335.85554 22272.47659 18995.58321 17305.05428 1.265430322 1.231262549 1.294808846 1.195215121 1.318216114 1.227878911 1.464072584 1.287050374 1.097689895 1 14.07890585 -13.00899594 0.173783766 2.22E-10 1.366627919 0.64430206 0.071129314 16.07851489 0.21227351 5.512895163 0.095934529 9.79E-14 13.00899594 1.366627919 ASVLDTSMSAGS(ph)GSPSK ddPTM_HeLa_Curcumin_4h_R1 2 ASVLDTSMSAGSGSPSK 17 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 ASVLDT(0.098)S(0.075)MS(0.164)AGS(0.559)GS(0.103)PSK;ASVLDTSMS(0.005)AGS(0.627)GS(0.36)PS(0.007)K ; 107.07 0.0016947 18895000 3530.4 2502.84 3172.5 2962.77 3194.38 3705 3202.2 2402.78 3156.88 2831.73 TRUE FALSE FALSE 3250.965115 2719.174337 3290.075641 2950.510843 3156.289105 2936.541236 3292.045114 3135.376561 2810.578162 2930.132407 1.10949427 0.928003912 1.122841969 1.006954783 1.077183098 1.002187215 1.123514114 1.070046034 0.959198347 1 11.51675014 -9.685777804 1.553229099 0.999971678 1.061926507 0.1728951 0.06042629 0.635491499 2.760264477 0.040080402 0.008886183 2.06E-10 9.685777804 0.061954829 ASVLDTSMSAGS(ph)GSPSKTVT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 ASVLDTSMSAGSGSPSKTVTPK 22 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 2 0 ASVLDT(0.045)S(0.117)MS(0.161)AGS(0.488)GS(0.2)PS(0.149)KT(0.284)VT(0.555)PK 58.858 0.01728 22933000 2762.4 2316.5 2148.7 2150.5 2523.5 4807 4999.5 1841.4 2539.5 1915.6 TRUE FALSE FALSE 2543.753125 2516.727938 2228.332712 2141.601801 2493.408911 3809.974014 5139.772515 2402.834383 2260.923204 1982.166957 1.283319306 1.269685144 1.124190222 1.080434619 1.257920732 1.922125682 2.593006858 1.212226031 1.140632072 1 10.95286277 -5.281339825 4.27315876 1.145975311 1.98711291 0.528653082 0.32099517 0.102747587 4.596056502 0.042350913 0.103894286 5.23E-06 5.281339825 0.841137599 ASVLDTSMSAGS(ph)GSPSKTVTPK ddPTM_HeLa_Curcumin_4h_R1 1 ASVLDTSMSAGSGSPSKTVTPK 22 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 ASVLDT(0.013)S(0.048)MS(0.055)AGS(0.799)GS(0.074)PS(0.01)KT(0.001)VTPK 65.278 0.0094771 84933000 3527.5 2053 2045.3 2937.7 1746.8 3645.1 3017.2 2153 3840.4 2826.9 TRUE FALSE FALSE 3248.294653 2230.452172 2121.100617 2925.544576 1725.970551 2889.065171 3101.854512 2809.439789 3419.117728 2925.134565 1.110476999 0.762512672 0.725129245 1.000140168 0.590048257 0.987669151 1.060414297 0.96044805 1.168875364 1 11.51428728 -7.271092649 24.97344642 1.052169695 0.870095639 0.326918959 0.143484283 671.4481045 1737063.784 0.024193748 0.027848225 5.36E-08 7.271092649 -0.182074057 ASVLDTSMSAGSGS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 ASVLDTSMSAGSGSPSK 17 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 ASVLDTSMSAGS(0.021)GS(0.957)PS(0.021)K 95.873 0.0029607 20758000 1771.8 968.87 1503.4 1288.8 1537.1 1959.5 1660.8 1328.2 1621.2 1562.7 TRUE FALSE FALSE 1631.56016 1052.614806 1559.117327 1283.467287 1518.771086 1553.077612 1707.397578 1733.162066 1443.358416 1617.003709 1.009002114 0.650966228 0.964201454 0.793731814 0.939250218 0.960466326 1.055902079 1.071835554 0.892612929 1 10.65910727 -4.74864049 4.470404235 0.95392841 1.067702089 0.137894357 0.112565017 0.3193638 15.20152059 0.016796996 0.062902383 1.78E-05 4.74864049 0.113773679 ASVLDTSMSAGSGS(ph)PSKTVT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 ASVLDTSMSAGSGSPSKTVTPK 22 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 2 0 ASVLDT(0.003)S(0.003)MS(0.04)AGS(0.157)GS(0.75)PS(0.14)KT(0.295)VT(0.613)PK 62.032 0.011892 21037000 4439.4 3727.6 3358.9 3793.3 3452.3 7222.6 6885.1 2633.6 4353.7 2478.5 TRUE FALSE FALSE 4088.016806 4049.797134 3483.383789 3777.60433 3411.133577 5724.551345 7078.277376 3436.572516 3876.110002 2564.627691 1.594000104 1.579097484 1.358241511 1.472964027 1.330069698 2.232117888 2.759962938 1.339988853 1.511373373 1 11.32453369 -1.000000001 0.061923164 6.25E-10 5.198383017 0.212427436 0.427942451 222.172506 1.036182612 17.47226546 103.9714009 0.1 1.000000001 5.198383016 ASVLDTSMSAGSGS(ph)PSKTVTPK ddPTM_HeLa_Curcumin_4h_R1 1 ASVLDTSMSAGSGSPSKTVTPK 22 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 ASVLDTS(0.001)MS(0.017)AGS(0.284)GS(0.697)PS(0.001)KTVTPK 102.21 2.97E-05 264530000 2911.5 1718 1533.6 1801.6 1090.4 2412.1 1698.1 1456.8 2707.5 2184.1 TRUE FALSE FALSE 2681.051703 1866.496265 1590.436565 1794.145457 1077.397692 1911.80327 1745.744116 1900.971614 2410.494024 2259.997312 1.186307474 0.825884285 0.70373383 0.793870615 0.476725209 0.845931656 0.772454067 0.841138882 1.066591544 1 11.14210534 -7.112275411 4.55616045 1.087335347 0.737730898 0.674522568 0.107198576 0.101019519 3.387351421 0.019503928 0.024115645 7.72E-08 7.112275411 -0.349604449 ASVLDTSMSAGSGSPS(ph)KTVTPK ddPTM_HeLa_Curcumin_4h_R1 1 ASVLDTSMSAGSGSPSKTVTPK 22 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 ASVLDTSMS(0.002)AGS(0.01)GS(0.173)PS(0.8)KT(0.012)VT(0.003)PK 101.38 3.74E-05 239780000 7968.5 5576 5631.1 6019.1 3547.9 7694.7 5756.7 3694.8 8794.9 6370.6 TRUE FALSE FALSE 7337.784817 6057.964594 5839.79352 5994.194559 3505.59361 6098.732483 5918.217509 4821.327511 7830.121474 6591.977876 1.113138569 0.918990432 0.88589398 0.909316547 0.531796932 0.925174902 0.897790863 0.731393157 1.187825812 1 12.68649569 -6.768130143 1.618291374 1.052430228 0.799111201 0.528937141 0.119378215 0.221855035 1.180791661 0.019594332 0.028505672 1.71E-07 6.768130143 -0.253319027 LLDS(ph)DSHTGK ddPTM_HeLa_Curcumin_4h_R1 1 LLDSDSHTGK 10 0 A0A087WX11;J3KNG8;Q8TF40-3;Q8TF40 A0A087WX11 FNIP1 Folliculin-interacting protein 1 1 0 LLDS(0.996)DS(0.004)HTGK 101.35 0.011681 7719900 2004.3 1863.5 2008 1972.9 2035.8 1797.6 835.62 569.68 2342.5 2317.5 TRUE FALSE FALSE 1845.65754 2024.572636 2082.418246 1964.736663 2011.524415 1424.757497 859.0652482 743.3728095 2085.533611 2398.032953 0.769654786 0.844263893 0.868386001 0.819311787 0.838822674 0.594135913 0.358237466 0.309992742 0.869685134 1 11.22763577 -4.983333559 1.554809223 0.880007167 0.285564255 0.933555102 0.056415941 0.113635242 0.492071144 0.013124474 0.067412414 1.04E-05 4.983333559 -0.594442911 down CPT(ph)PVGDGSSSR ddPTM_HeLa_Curcumin_4h_R1 1 CPTPVGDGSSSR 12 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 0 CPT(1)PVGDGSSSR 121.21 0.0099781 9934700 2533.3 3080.5 3207.4 2956.2 2658.1 2535.6 1497.1 865.57 3307.2 3101.1 TRUE FALSE FALSE 2332.786632 3346.764694 3326.269066 2943.968028 2626.403894 2009.687978 1539.104597 1129.478308 2944.408434 3208.862994 0.72698231 1.042975253 1.03658806 0.917448963 0.818484273 0.626292859 0.47964173 0.351987078 0.91758621 1 11.64784648 -4.980182067 1.489138673 0.899127865 0.363514902 0.839833029 0.091362602 0.189757307 0.741502011 0.018621933 0.100050641 1.05E-05 4.980182067 -0.535612963 down ASVS(ph)PMDEPVPDSES(ph)PIEK ddPTM_HeLa_Curcumin_4h_R1 2 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 AS(0.452)VS(0.548)PMDEPVPDS(0.295)ES(0.705)PIEK;AS(0.159)VS(0.841)PMDEPVPDS(0.374)ES(0.626)PIEK ; 110.55 0.00063556 20413000 8177.7 7586.6 7836.9 8072.5 7824.2 8928.7 7908.5 9490 8139.2 7319.8 TRUE FALSE FALSE 7530.426416 8242.351899 8127.342408 8039.098134 7730.901525 7076.786973 8130.391225 12383.45731 7246.350123 7574.162505 0.99422562 1.088219575 1.073035125 1.061384427 1.020693908 0.934332604 1.073437653 1.634960605 0.956719653 1 12.88687066 -4.26568934 4.086424384 1.011683857 1.685763239 0.939874092 0.046656267 0.035859634 1.285625607 0.006436787 0.070531083 5.42E-05 4.26568934 0.674079383 ASVS(ph)PMDEPVPDSESPIEK ddPTM_HeLa_Curcumin_4h_R1 7 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 AS(0.011)VS(0.989)PMDEPVPDSESPIEK;AS(0.271)VS(0.729)PMDEPVPDSESPIEK;AS(0.027)VS(0.973)PMDEPVPDSESPIEK;AS(0.081)VS(0.919)PMDEPVPDSESPIEK;AS(0.024)VS(0.976)PMDEPVPDSESPIEK;ASVS(1)PMDEPVPDSESPIEK;AS(0.029)VS(0.971)PMDEPVPDSESPIEK ;;;;;; 286.85 8.25E-83 599015000 40704.7 33807 35956.2 35647.4 32743.6 38189.3 29576.91 35334.6 39874.9 34603.9 TRUE FALSE FALSE 37482.88004 36729.12644 37288.7684 35499.9005 32353.15396 30268.4087 30406.75849 46107.95688 35500.72323 35806.38295 1.04682118 1.025770363 1.041400033 0.991440564 0.903558285 0.845335558 0.849199388 1.287702166 0.991463541 1 15.12792917 -5.996853334 23.22736629 1.023976165 0.952932485 0.028692196 0.118028318 83.28554832 614745.531 0.016373616 0.029542107 1.01E-06 5.996853334 -0.07104368 ASVSGPNS(ph)PSETR ddPTM_HeLa_Curcumin_4h_R1 1 ASVSGPNSPSETR 13 0 C9J453;A0A087X255;O15344-2;O15344;A0A087X0X0 C9J453 MID1 E3 ubiquitin-protein ligase Midline-1 1 0 ASVSGPNS(0.958)PS(0.04)ET(0.002)R 176.43 0.00021375 25038000 2003.6 1832.8 1727.3 1901.8 2203.2 2264.5 1732.1 907.02 1899.5 1953.6 TRUE FALSE FALSE 1845.012946 1991.219065 1791.315257 1893.930856 2176.928279 1794.817174 1780.698064 1183.566223 1691.129602 2021.487455 0.912700666 0.985026675 0.886137212 0.936899634 1.076894281 0.887869559 0.880885043 0.585492737 0.836576848 1 10.98120153 -4.079312189 1.620389456 0.95869516 0.306822003 0.719640651 0.065638096 0.532317758 0.919510513 0.007930281 0.623244004 8.33E-05 4.079312189 -0.651873157 ASVSGPNS(ph)PSETRR ddPTM_HeLa_Curcumin_4h_R1 1 ASVSGPNSPSETRR 14 1 C9J453;A0A087X255;O15344-2;O15344;A0A087X0X0 C9J453 MID1 E3 ubiquitin-protein ligase Midline-1 1 0 ASVSGPNS(0.698)PS(0.055)ET(0.247)RR 79.332 0.0092375 5977600 1017.6 1157.8 734.05 763.59 1109.3 1080.2 813.02 501.7 1173.5 933.76 TRUE FALSE FALSE 937.0558862 1257.875073 761.2545387 760.4304669 1096.072322 856.1543436 835.8311531 654.6660205 1044.769986 966.2080905 0.969828234 1.301867667 0.787878456 0.787025564 1.134406069 0.886097262 0.865063294 0.677562139 1.081309499 1 9.916190123 -3.566680596 0.796796252 0.991392612 1.74E-13 0.324163879 0.14620957 5.896040624 1.234668238 0.022021573 6.741545462 0.000271219 3.566680596 -0.991392612 KDS(ph)SSVVEWTQAPK ddPTM_HeLa_Curcumin_4h_R1 1 KDSSSVVEWTQAPK 14 1 Q8TC07-2;Q8TC07-3;Q8TC07;F8WCB5 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 0 KDS(0.828)S(0.086)S(0.086)VVEWTQAPK 116.04 0.00093728 0 648.18 587.89 539.01 549.09 543.24 730.98 1142.4 1423.5 743.4 544.19 TRUE FALSE FALSE 596.875869 638.704592 558.9861848 546.8180111 536.7622178 579.3665082 1174.452669 1857.518597 661.8508799 563.100562 1.059980951 1.134263816 0.992693353 0.971084115 0.953226216 1.028886397 2.085689038 3.298733339 1.175368885 1 9.137248781 -4.443202433 2.088126545 1.019752265 3.520422069 0.985107014 0.087579943 0.033871013 0.212117301 0.011335161 0.137358219 3.60E-05 4.443202433 2.500669804 up NDSWGS(ph)FDLR ddPTM_HeLa_Curcumin_4h_R1 2 NDSWGSFDLR 10 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 NDS(0.188)WGS(0.812)FDLR;NDS(0.237)WGS(0.763)FDLR ; 138.42 0.0017283 15197000 2987.65 2556.81 2915.97 2773.15 3455.5 8154 9108.2 11001.5 2991.9 2876.73 TRUE FALSE FALSE 2751.17435 2777.809263 3024.038413 2761.67544 3414.295419 6462.768485 9363.751579 14355.80671 2663.696055 2976.696153 0.924237547 0.933185357 1.015904297 0.927765314 1.147008376 2.171121321 3.145686055 4.822731635 0.894849833 1 11.53949625 -4.441419062 1.041845006 0.94849983 6.078437053 0.993923257 0.097866835 0.069824603 0.072240432 0.015119245 0.367881636 3.62E-05 4.441419062 5.129937222 up ASVSQT(ph)SPQSASSPR ddPTM_HeLa_Curcumin_4h_R1 2 ASVSQTSPQSASSPR 15 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 0 ASVS(0.003)QT(0.876)S(0.093)PQS(0.003)AS(0.007)S(0.017)PR;ASVS(0.014)QT(0.466)S(0.466)PQS(0.052)AS(0.002)SPR ; 216.77 8.04E-14 63019000 9679.6 7771.7 8207.9 8593.8 8277.5 8373 4741.2 4222.5 9796.8 8081.9 TRUE FALSE FALSE 8913.449446 8443.451118 8512.091994 8558.241133 8178.796219 6636.345417 4874.225312 5509.920812 8722.11555 8362.745423 1.065852061 1.009650622 1.017858558 1.023376977 0.97800373 0.793560617 0.582849897 0.658865066 1.042972745 1 13.02976093 -5.103478342 2.091746238 1.028204558 0.615747098 0.969687185 0.028726685 0.040042643 0.335320566 0.004653869 0.016540493 7.88E-06 5.103478342 -0.41245746 ITSISPT(ph)PEPPAALEDNPDAWGDGSPR ddPTM_HeLa_Curcumin_4h_R1 1 ITSISPTPEPPAALEDNPDAWGDGSPR 27 0 Q14934-2;Q14934-9;Q14934-3;Q14934-4;Q14934-5;Q14934-6;Q14934-7;Q14934;Q14934-8;Q14934-10;Q14934-18;Q14934-11;Q14934-12;Q14934-13;Q14934-14;Q14934-15;Q14934-16;Q14934-17;G3V5H0 Q14934-2 NFATC4 "Nuclear factor of activated T-cells, cytoplasmic 4" 1 0 IT(0.069)S(0.076)IS(0.401)PT(0.454)PEPPAALEDNPDAWGDGSPR 90.323 7.59E-06 4522100 1568.6 1229.1 1343.8 1491.4 1595.2 1297.4 827.35 441.5 1645 1612.7 TRUE FALSE FALSE 1444.443655 1335.337927 1393.60241 1485.228982 1576.178282 1028.304615 850.5632143 576.1113176 1464.547616 1668.741205 0.865588775 0.800206721 0.835121951 0.890029549 0.944531289 0.616215751 0.509703489 0.345237066 0.877636155 1 10.70454452 -4.93210371 1.581430404 0.916188776 0.365288551 0.886094713 0.067114459 0.114692623 0.51066496 0.012011917 0.065566393 1.17E-05 4.93210371 -0.550900225 down ASWES(ph)LDEEWR ddPTM_HeLa_Curcumin_4h_R1 2 ASWESLDEEWR 11 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 0 AS(0.301)WES(0.699)LDEEWR;AS(0.013)WES(0.987)LDEEWR ; 255.41 5.55E-33 43802000 4978.3 4569.9 4282.2 4072.6 4876.4 4377.7 3820.4 1929.17 4131.5 3565.1 TRUE FALSE FALSE 4584.262302 4964.901793 4440.902099 4055.74866 4818.252115 3469.715673 3927.590142 2517.365052 3678.284787 3688.98696 1.242688671 1.345871332 1.203826998 1.099420709 1.306117958 0.940560569 1.064679866 0.682400095 0.997098886 1 11.84900897 -3.834082138 1.13456674 1.147773379 2.49E-15 0.553014687 0.125852395 2.417012504 1.305657693 0.020471249 4.170040096 0.000146527 3.834082138 -1.147773379 (ac)AS(ph)KEMFEDTVEER ddPTM_HeLa_Curcumin_4h_R1 3 ASKEMFEDTVEER 13 1 E9PC52;Q16576 E9PC52 RBBP7 Histone-binding protein RBBP7 1 0 AS(1)KEMFEDTVEER;AS(0.995)KEMFEDT(0.005)VEER;AS(1)KEMFEDTVEER ;; 61.419 0.00096838 25227600 2963.03 2171.34 2399.63 2300.03 2962.79 2826.83 5402.7 7007.7 3495.71 2984.31 TRUE FALSE FALSE 2728.503049 2359.020954 2488.562399 2290.513085 2927.460664 2240.513593 5554.285221 9144.315471 3112.239359 3088.01455 0.88357843 0.763928057 0.805877809 0.74174297 0.948007406 0.725551501 1.798659019 2.961228103 1.007844784 1 11.59246384 -4.429517277 2.416913867 0.894268695 3.100265025 0.966496097 0.122353322 0.050088483 0.447242527 0.018281941 0.194735893 3.72E-05 4.429517277 2.205996331 up NSPQS(ph)SPTSTPK ddPTM_HeLa_Curcumin_4h_R1 2 NSPQSSPTSTPK 12 0 Q9Y6Y0 Q9Y6Y0 IVNS1ABP Influenza virus NS1A-binding protein 1 0 NSPQS(0.76)S(0.22)PT(0.015)S(0.004)TPK;NSPQS(0.499)S(0.499)PT(0.001)STPK ; 193.45 4.00E-06 80758000 16897.5 13928.6 13294.8 15124.1 13905.6 12556.6 6682 3671.9 14457.3 12926.7 TRUE FALSE FALSE 15560.04504 15132.52612 13787.51698 15061.52048 13739.7848 9952.219618 6869.478936 4791.445407 12871.37036 13375.90186 1.163289414 1.131327538 1.030772887 1.126019063 1.027204367 0.744041016 0.513571272 0.358214755 0.962280562 1 13.70734855 -4.929549906 1.537547561 1.084574382 0.357759496 0.944207035 0.061953363 0.075712971 0.314936327 0.010051725 0.056586958 1.18E-05 4.929549906 -0.726814885 down AT(ph)PPPS(ph)PLLSELLKK ddPTM_HeLa_Curcumin_4h_R1 2 ATPPPSPLLSELLKK 15 1 Q9H0E9-4;Q9H0E9-2;H7C128;H7C179;H7C127;Q9H0E9-3 Q9H0E9-4;Q9H0E9-3 BRD8 Bromodomain-containing protein 8 2 0 AT(1)PPPS(1)PLLSELLKK;AT(1)PPPS(1)PLLSELLKK ; 82.755 0.0038282 1564100 4309.84 3381.46 3065.27 3462.8 3364.6 4697.6 3939.6 5408.9 4216.05 4263.9 TRUE FALSE FALSE 3968.711616 3673.738335 3178.871603 3448.471851 3324.479342 3723.264807 4050.134573 7058.04871 3753.559863 4412.070208 0.899512344 0.832656364 0.720494338 0.781599496 0.753496474 0.843881587 0.917966937 1.599713599 0.85074799 1 12.10724003 -4.261858343 5.721557795 0.893767852 1.622102372 0.857633491 0.090377257 0.049794998 6.900726694 0.01610202 0.140928924 5.47E-05 4.261858343 0.72833452 AT(ph)PPPSPLLSELLK ddPTM_HeLa_Curcumin_4h_R1 2 ATPPPSPLLSELLK 14 0 Q9H0E9-4;Q9H0E9-2;H7C128;H7C179;H7C127;Q9H0E9-3 Q9H0E9-4;Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 0 AT(1)PPPSPLLSELLK;AT(1)PPPSPLLSELLK ; 183.06 0.00025283 303260000 2337.76 2074.84 2322.28 2488.39 2473.32 2933.3 2647.15 1803.41 2362.77 2368.46 TRUE FALSE FALSE 2152.723829 2254.179924 2408.34574 2478.093702 2443.827274 2324.900515 2721.421905 2353.261407 2103.580042 2450.763809 0.878388942 0.919786687 0.982691898 1.011151582 0.997169644 0.948643238 1.110438262 0.960215505 0.858336505 1 11.25901574 -6.573730192 4.433200967 0.939369396 1.007032488 0.345451707 0.055488754 0.24032217 10.08647585 0.00936398 0.013531388 2.67E-07 6.573730192 0.067663092 AT(ph)PPPSPLLSELLKK ddPTM_HeLa_Curcumin_4h_R1 1 ATPPPSPLLSELLKK 15 1 Q9H0E9-4;Q9H0E9-2;H7C128;H7C179;H7C127;Q9H0E9-3 Q9H0E9-4;Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 0 AT(0.999)PPPS(0.001)PLLSELLKK 64.52 0.019997 44955000 2997.8 2155.5 2572.5 2638.7 2284.1 3423 2708.4 2215.8 2670.5 2827.9 TRUE FALSE FALSE 2760.520967 2341.811815 2667.839113 2627.781759 2256.863599 2713.031215 2784.390415 2891.38722 2377.552831 2926.169315 0.943390717 0.800299492 0.911717275 0.898027925 0.771268972 0.927161392 0.951547951 0.988113437 0.81251376 1 11.51479753 -7.762718523 2.004321636 0.981399593 0.892396826 0 0.082217684 0.285106449 2.38852507 0.013095217 0.012823218 1.73E-08 7.762718523 -0.089002766 AT(ph)PSENLVPSSAR ddPTM_HeLa_Curcumin_4h_R1 1 ATPSENLVPSSAR 13 0 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 0 AT(0.863)PS(0.137)ENLVPSSAR 101.72 0.017852 29832000 878.2 677.39 827.87 928.96 834.44 945.03 1080.6 687.48 1059.1 777.93 TRUE FALSE FALSE 808.6895433 735.9405732 858.5515905 925.1162097 824.489848 749.0201253 1110.918728 897.0894872 942.9193797 804.9630096 1.004629447 0.914253903 1.066572725 1.149265492 1.024258057 0.93050254 1.38008668 1.114448088 1.171382248 1 9.652778678 -4.769527001 24.99997989 1.008789967 1.247267402 0.408479518 0.100095121 79.9694041 247199.94 0.011140288 0.034278921 1.70E-05 4.769527001 0.238477435 S(ph)LNPALDGLTCGLTSHDKR ddPTM_HeLa_Curcumin_4h_R1 2 SLNPALDGLTCGLTSHDKR 19 1 A0A0A0MRE6;O94967-2;O94967;O94967-3;O94967-4 A0A0A0MRE6 WDR47 WD repeat-containing protein 47 1 0 S(1)LNPALDGLTCGLTSHDKR;S(1)LNPALDGLTCGLTSHDKR ; 81.51 0.0038774 44684000 6121 5487.8 5833.2 6354.9 5430.6 5332.8 2423.4 1411.36 5296.5 6216.4 TRUE FALSE FALSE 5636.516391 5962.140979 6049.383523 6328.605108 5365.843642 4226.717167 2491.394082 1841.677167 4715.487201 6432.419437 0.876266924 0.926889336 0.94045228 0.983860765 0.834187462 0.657096013 0.38731835 0.286311735 0.733081424 1 12.65114577 -4.926109282 1.420430696 0.942075355 0.258402838 0.899637448 0.075080492 0.067740546 0.232079544 0.00754579 0.046202692 1.19E-05 4.926109282 -0.683672517 down AT(ph)SGSSLPVGINR ddPTM_HeLa_Curcumin_4h_R1 1 ATSGSSLPVGINR 13 0 Q13905-2;Q13905;Q13905-4;Q13905-3 Q13905-2 RAPGEF1 Rap guanine nucleotide exchange factor 1 1 0 AT(0.974)S(0.025)GSSLPVGINR 148.89 0.001745 9021100 2927.6 2459.2 2819.6 2720.7 2866.6 3921.2 3042.8 1600.3 2905.1 2554.9 TRUE FALSE FALSE 2695.877371 2671.76229 2924.096856 2709.442464 2832.417667 3107.898919 3128.172779 2088.224103 2586.417798 2643.682585 1.019743212 1.010621436 1.106069569 1.024874348 1.071390977 1.17559458 1.183263375 0.789892143 0.978339008 1 11.36833325 -6.792531563 21.78193574 1.009680966 1.068562592 0.059762418 0.103330028 101.3326773 70988.77529 0.015558791 0.020451192 1.61E-07 6.792531563 0.058881626 AT(ph)SNVFAMFDQSQIQEFK ddPTM_HeLa_Curcumin_4h_R1 4 ATSNVFAMFDQSQIQEFK 18 0 J3QRS3;P19105;O14950;J3KTJ1;P24844;P24844-2 J3QRS3;P24844 MYL12A;MYL12B;MYL9 Myosin regulatory light chain 12A;Myosin regulatory light chain 12B;Myosin regulatory light polypeptide 9 1 0 AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.556)S(0.444)NVFAMFDQSQIQEFK;AT(0.5)S(0.5)NVFAMFDQSQIQEFK;AT(0.5)S(0.5)NVFAMFDQSQIQEFK ;;; 157.9 5.07E-05 285173700 15740.8 12837.1 16236.7 15202.4 16269.1 35638.1 25166.3 11588.04 14936.2 12578.71 TRUE FALSE FALSE 14494.89907 13946.68172 16838.44639 15139.4965 16075.10161 28246.35634 25872.39865 15121.18005 13297.73623 13015.81924 1.113637091 1.071517779 1.29369086 1.163161244 1.235043397 2.170155856 1.98776567 1.161753999 1.021659566 1 13.6679785 -5.426409169 5.751212865 1.087287557 1.791706583 0.578433405 0.253297079 0.110113815 5.33104436 0.034860195 0.078674287 3.75E-06 5.426409169 0.704419026 AT(ph)SPSKS(ph)VAHGQAPEMPLVKKK ddPTM_HeLa_Curcumin_4h_R1 1 ATSPSKSVAHGQAPEMPLVKKK 22 3 Q1ED39;H3BMC9 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 2 0 AT(0.491)S(0.491)PS(0.491)KS(0.527)VAHGQAPEMPLVKKK 43.116 0.0093296 0 524.83 423.2 243.58 305.73 464.89 485.01 349.4 216.81 282.51 405.97 TRUE FALSE FALSE 483.2891517 459.7795223 252.6072891 304.4649703 459.3464904 384.4134588 359.2032236 282.9143709 251.5193598 420.0774273 1.150476365 1.094511374 0.60133507 0.724782982 1.093480536 0.91510144 0.855088134 0.673481488 0.598745239 1 8.714511455 -6.802259842 24.9998769 1.074802835 0.826284448 0.002299825 0.200675536 107.981348 66131.16039 0.022991032 0.030216324 1.58E-07 6.802259842 -0.248518388 AT(ph)VLASS(ph)Y(ph)DT(ph)AWKK ddPTM_HeLa_Curcumin_4h_R1 1 ATVLASSYDTAWKK 14 1 Q96Q15;J3KRA9;Q96Q15-4;Q96Q15-3;Q96Q15-2 Q96Q15 SMG1 Serine/threonine-protein kinase SMG1 4 0 AT(0.819)VLAS(0.339)S(0.851)Y(0.992)DT(1)AWKK 45.704 0.018076 9174000 1849.7 1664.2 1629.8 2128.7 1823.2 3119.4 2277.5 1368.9 1802.2 1727 TRUE FALSE FALSE 1703.294293 1808.046032 1690.201822 2119.892003 1801.459531 2472.401277 2341.40052 1786.271308 1604.503169 1787.013121 0.953151531 1.011769869 0.945825076 1.186276686 1.008084109 1.383538401 1.310231297 0.999584887 0.897868712 1 10.80333451 -5.917879098 1.390376676 0.97785958 1.221096205 0.445757013 0.116605102 0.262023942 1.012175863 0.017124866 0.039301294 1.21E-06 5.917879098 0.243236624 ATAGDTHLGGEDFDNR ddPTM_HeLa_Curcumin_4h_R1 5 ATAGDTHLGGEDFDNR 16 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;Q53FA3;P34931;P17066;P48741 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA1L;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 1-like;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 0 ;;;; ;;;; 140.77 0.00010469 513374000 27466.9 20741.2 23747.1 23792.9 24130.7 32924.8 23686.3 23947.8 27215.1 22230.6 FALSE FALSE TRUE 25292.86588 22533.97691 24627.18842 23694.45128 23842.95716 26095.82534 24350.87383 31249.37398 24229.67162 23003.1117 1.099541063 0.979605594 1.070602479 1.030054177 1.036510081 1.134447621 1.058590427 1.358484643 1.053321478 1 14.48954141 -1.622186173 1.179860118 1.044809678 199.9999997 0.815787762 0.043554501 334.5763266 0.940804477 0.007128367 179580.9292 0.023867879 1.622186173 198.95519 ATAPQT(ph)QHVSPMRQVEPPAK ddPTM_HeLa_Curcumin_4h_R1 1 ATAPQTQHVSPMRQVEPPAK 20 1 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;P29692-4;E9PQZ1;E9PL12;E9PPR1;E9PK06 P29692 EEF1D Elongation factor 1-delta 1 0 AT(0.002)APQT(0.634)QHVS(0.363)PMRQVEPPAK 59.242 0.01013 34237000 3877.2 2808.8 2732.9 3404.1 2250.3 4607.7 4178.4 5061.9 5169.5 3768.1 TRUE FALSE FALSE 3570.315529 3051.580156 2834.183678 3390.014736 2223.466642 3652.011081 4295.634658 6605.250008 4602.418783 3899.041195 0.915690641 0.782648863 0.726892468 0.869448299 0.570259849 0.936643369 1.101715638 1.694070331 1.180397578 1 11.92890368 -4.273686285 2.248029258 0.89479372 1.884156551 0.71763208 0.1553199 0.235589206 1.387860541 0.020726611 0.455602668 5.32E-05 4.273686285 0.989362831 ATAPQTQ ddPTM_HeLa_Curcumin_4h_R1 1 ATAPQTQ 7 0 E9PMW7;E9PN91;H0YCK7 E9PMW7 EEF1D 0 0 134.81 0.01689 3956700 2271.9 1915.4 2176.1 2242.8 2088.6 2493.5 2146.5 1406.5 2420.2 2387 FALSE FALSE TRUE 2092.076718 2080.958641 2256.74818 2233.519888 2063.694809 1976.319992 2206.725013 1835.335375 2154.710115 2469.948072 0.84701243 0.842511089 0.91368244 0.904278075 0.835521537 0.800146373 0.893429719 0.743066381 0.872370613 1 11.270265 -13.52287875 0.194389558 1.701421037 0.818150013 0.154119841 0.060848882 25.02825582 0.299526333 6.643301506 0.050293499 3.00E-14 13.52287875 -0.883271024 ATAPQTQHVS(ph)PMR ddPTM_HeLa_Curcumin_4h_R1 17 ATAPQTQHVSPMR 13 0 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;P29692-4;E9PQZ1;E9PL12;E9PPR1;E9PK06 P29692 EEF1D Elongation factor 1-delta 1 0 ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.001)QHVS(0.999)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR;ATAPQT(0.001)QHVS(0.999)PMR;ATAPQT(0.004)QHVS(0.996)PMR;ATAPQTQHVS(1)PMR;ATAPQTQHVS(1)PMR ;;;;;;;;;;;;;;;; 142.95 0.00086355 25451314400 62922.28 53830.26 55256.95 59058.03 57868.43 68932.85 51087.38 38351.82 63092.34 54714.41 TRUE FALSE FALSE 57941.91514 58483.10781 57304.82118 58813.66352 57178.38677 54635.39988 52520.75439 50045.11337 56171.26815 56615.73167 1.023424293 1.032983344 1.012171343 1.038821928 1.00993814 0.965021528 0.927670682 0.883943595 0.99214947 1 15.78891537 -4.781333752 1.506768504 1.015404671 0.882322107 0.910629529 0.0140473 0.108167407 0.401034044 0.002147532 0.01603032 1.65E-05 4.781333752 -0.133082564 ATAPQTQHVS(ph)PMRQVEPPAK ddPTM_HeLa_Curcumin_4h_R1 2 ATAPQTQHVSPMRQVEPPAK 20 1 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;P29692-4;E9PQZ1;E9PL12;E9PPR1;E9PK06 P29692 EEF1D Elongation factor 1-delta 1 0 ATAPQT(0.001)QHVS(0.999)PMRQVEPPAK;ATAPQT(0.019)QHVS(0.98)PMRQVEPPAK ; 82.146 0.0055511 108234000 7102.9 4402.9 3810.9 5664 3084.6 7224.6 3999.5 3278.7 9210.9 7622.9 TRUE FALSE FALSE 6540.69797 4783.467057 3952.135306 5640.563869 3047.81816 5726.136522 4111.715206 4278.360537 8200.487315 7887.795208 0.829217519 0.606439053 0.501044361 0.715100192 0.386396715 0.725948934 0.521275603 0.542402588 1.039642524 1 12.94540638 -7.511659303 1.050517721 0.955131781 0.559470633 0.751216135 0.102785781 0.152866014 0.341480217 0.021632122 0.022697669 3.08E-08 7.511659303 -0.395661148 ATASSSAQEMEQQLAER ddPTM_HeLa_Curcumin_4h_R1 1 ATASSSAQEMEQQLAER 17 0 J3QT73;A0A087X1P5;J3KQ34;Q9H9Q2-2;Q9H9Q2 J3QT73 COPS7B COP9 signalosome complex subunit 7b 0 0 137.95 0.0018526 6909000 769.24 725.93 857.41 1000.6 981.68 944.38 751.21 849.76 915.19 858.11 FALSE FALSE TRUE 708.3538423 788.6761545 889.1863689 996.4597823 969.9741072 748.5049426 772.2869308 1108.847912 814.7959467 887.9292586 0.797759321 0.888219582 1.001415777 1.122228795 1.092400208 0.842978126 0.869761778 1.248802088 0.917636105 1 9.794300931 -6.703943221 5.512273145 0.900606261 1.022132696 0.217501562 0.119466322 0.283712851 17.61768937 0.020940129 0.029534475 1.98E-07 6.703943221 0.121526435 ATATISAK(ac)PQITNPK ddPTM_HeLa_Curcumin_4h_R1 2 ATATISAKPQITNPK 15 1 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 0 1 ; ATATISAK(1)PQITNPK;ATATISAK(1)PQITNPK 315.43 5.28E-154 13441900 8194.5 5863.2 6566.1 7159.4 7135 8456.8 8616.7 9108.3 7884.9 6691.3 FALSE TRUE FALSE 7545.896678 6369.988882 6809.445442 7129.7763 7049.919785 6702.764352 8858.461411 11885.37874 7019.946197 6923.822177 1.089845534 0.920010468 0.983480694 1.029745727 1.018212138 0.968072862 1.279417811 1.716592142 1.013883086 1 12.75735296 -4.367411912 2.380733582 1.023673687 1.798774438 0.951696806 0.049382607 0.075056226 0.596021861 0.008014031 0.10780323 4.29E-05 4.367411912 0.775100751 ATAVMPDGQFK ddPTM_HeLa_Curcumin_4h_R1 4 ATAVMPDGQFK 11 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 0 ;;; ;;; 133.75 0.00057695 156840200 28023.7 23977 25348.8 23978.7 24848.7 35232.7 26602.6 26179.9 25247.6 23952.4 FALSE FALSE TRUE 25805.59457 26049.46504 26288.24883 23879.48249 24552.39548 27925.04087 27348.99736 34162.03099 22478.00145 24784.74412 1.041188662 1.051028202 1.060662507 0.963475047 0.990625337 1.126702811 1.103460953 1.37834915 0.906928929 1 14.59716474 -3.07270173 0.95006394 1.02052292 4.096128606 0.816497476 0.052329712 3.653508509 0.432076961 0.005927298 19.41428699 0.00084586 3.07270173 3.075605686 ATAVVDGAFK ddPTM_HeLa_Curcumin_4h_R1 2 ATAVVDGAFK 10 0 P32119;A6NIW5;P32119-2 P32119 PRDX2 Peroxiredoxin-2 0 0 ; ; 138.08 0.00035191 15027200 13899.9 10180.6 12536.9 12232.3 12849.8 15920.9 13484.5 12351.5 12945.2 11339.3 FALSE FALSE TRUE 12799.70825 11060.5657 13001.52854 12181.68598 12696.57453 12618.72587 13862.83878 16117.41549 11525.14395 11733.33983 1.090883622 0.942661327 1.108084205 1.038211299 1.082093821 1.075458996 1.181491287 1.373642605 0.982256042 1 13.51832611 -3.215231703 0.81716071 1.039734792 2.861816419 0.831347087 0.047443299 3.171266317 0.42854097 0.007435138 7.834388689 0.000609212 3.215231703 1.822081627 ATCAPQHGAPGPGPADASK ddPTM_HeLa_Curcumin_4h_R1 2 ATCAPQHGAPGPGPADASK 19 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 149.42 6.41E-05 33518000 16686.9 12332.5 14638.3 14312.5 15074.6 18493.7 13577.2 11882 17082.3 15498.2 FALSE FALSE TRUE 15366.11426 13398.46635 15180.80828 14253.27867 14894.84524 14657.89815 13958.13969 15504.7671 15208.41443 16036.7613 0.958180643 0.835484553 0.946625568 0.888787855 0.928793848 0.914018603 0.870383953 0.966826581 0.948346998 1 13.96909519 -7.497427589 5.496335544 0.982144414 0.90689928 0.361437414 0.037417093 0.11077723 8.708080579 0.006004892 0.006612842 3.18E-08 7.497427589 -0.075245134 ATDDDMQSLASLMSVKPSDVGNLDDFAES(ph)DEDEAHGPGAPEAR ddPTM_HeLa_Curcumin_4h_R1 1 ATDDDMQSLASLMSVKPSDVGNLDDFAESDEDEAHGPGAPEAR 43 1 Q8N3D4;E9PIH6;A0A0U1RQH4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 0 ATDDDMQS(0.019)LAS(0.233)LMS(0.046)VKPS(0.092)DVGNLDDFAES(0.609)DEDEAHGPGAPEAR 49.664 0.00094224 34754000 1276 1067 1392.2 1026.4 1224.5 1508.3 911.04 724.53 1462.2 985.07 TRUE FALSE FALSE 1175.003254 1159.226726 1443.796157 1022.153029 1209.898637 1195.461578 936.6013305 945.4358617 1301.800318 1019.301109 1.152753826 1.137276037 1.416456966 1.002797917 1.186988444 1.172824759 0.918866194 0.927533438 1.277149908 1 9.993364582 -4.750473297 24.76825051 1.111466439 0.923199672 0.309795211 0.125132182 194.0738237 438329.4121 0.01711017 0.062752132 1.78E-05 4.750473297 -0.188266766 ATDIPASAS(ph)PPPVAGVPFFK ddPTM_HeLa_Curcumin_4h_R1 2 ATDIPASASPPPVAGVPFFK 20 0 Q8N1G0;Q8N1G0-2;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 0 ATDIPAS(0.002)AS(0.998)PPPVAGVPFFK;ATDIPAS(0.033)AS(0.967)PPPVAGVPFFK ; 176.17 2.45E-07 108367000 12225.5 10769.2 11761.6 10894.5 11784.2 12768.8 11885.6 6579.8 10820.3 9713.3 TRUE FALSE FALSE 11257.83877 11700.04166 12197.49524 10849.42145 11643.68111 10120.40695 12219.07795 8585.95073 9633.340161 10050.83645 1.120089739 1.164086364 1.213580114 1.07945458 1.158478816 1.006921861 1.215727468 0.854252357 0.958461538 1 13.29502795 -2.603923658 14.42684517 1.079335886 0.61379698 0 0.113376581 0 0 0.013635661 0 0.002489295 2.603923658 -0.465538906 ATDS(ph)FSGR ddPTM_HeLa_Curcumin_4h_R1 1 ATDSFSGR 8 0 K7EK27;Q9HBH9-2;Q9HBH9 K7EK27 MKNK2 MAP kinase-interacting serine/threonine-protein kinase 2 1 0 AT(0.021)DS(0.952)FS(0.027)GR 90.827 0.020422 17083000 3409.8 3250 3586.7 3648.8 4009.6 3601.1 1547.6 1361.3 3384 2936.5 TRUE FALSE FALSE 3139.910732 3530.915518 3719.626257 3633.702232 3961.788139 2854.191267 1591.021491 1776.354103 3012.783666 3038.543156 1.033360584 1.162042247 1.224147911 1.195869878 1.303844617 0.939328856 0.523613261 0.584607166 0.991522421 1 11.56916407 -4.85387698 4.200531856 1.075194817 0.552126037 0.810399592 0.10766467 0.077977435 2.492132566 0.017744042 0.05932273 1.40E-05 4.85387698 -0.523068781 ATDSDLSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 ATDSDLSSPR 10 0 Q9BRD0;Q9BRD0-2 Q9BRD0 BUD13 BUD13 homolog 1 0 ATDSDLS(0.075)S(0.925)PR 146.71 0.0010379 86504000 6379.5 5445.9 5178 5299.7 5262.4 6877 5946.8 4068.2 7087.1 5658.8 TRUE FALSE FALSE 5874.555843 5916.61933 5369.901235 5277.771246 5199.649317 5450.63268 6113.651203 5308.575452 6309.662861 5855.442879 1.003264136 1.010447792 0.917078579 0.901344502 0.888002739 0.930865998 1.044097147 0.906605284 1.077572268 1 12.51556258 -6.76539072 24.99970002 1.00225245 0.933104231 0.454322541 0.046981504 77.2131567 488519.3353 0.006641394 0.008909338 1.72E-07 6.76539072 -0.069148219 ATEDGEEDEEMIES(ph)IENLEDLKGHSVR ddPTM_HeLa_Curcumin_4h_R1 2 ATEDGEEDEEMIESIENLEDLKGHSVR 27 1 P49736;H0Y8E6 P49736 MCM2 DNA replication licensing factor MCM2 1 0 ATEDGEEDEEMIES(0.999)IENLEDLKGHS(0.001)VR;ATEDGEEDEEMIES(1)IENLEDLKGHSVR ; 140.51 1.72E-08 14462700 4034.3 3300 4039 3838.8 4191.3 4760.5 3772.2 4134.2 4666.4 3959.6 TRUE FALSE FALSE 3714.980898 3585.237295 4188.688893 3822.916063 4141.321485 3773.118638 3878.03778 5394.698548 4154.507595 4097.195805 0.906713048 0.875046609 1.02233066 0.933056716 1.010769727 0.92090269 0.946510239 1.316680677 1.013988052 1 12.00042113 -4.260771676 24.96523398 0.95347985 1.316680791 0.829052949 0.048696808 15.85335779 592621.2305 0.006763665 0.053891296 5.49E-05 4.260771676 0.363200941 ATEDGEEDEEMIESIENLEDLKGHSVR ddPTM_HeLa_Curcumin_4h_R1 3 ATEDGEEDEEMIESIENLEDLKGHSVR 27 1 P49736;H0Y8E6 P49736 MCM2 DNA replication licensing factor MCM2 0 0 ;; ;; 188.24 1.01E-16 15881800 5368.1 4402.8 5115.1 5459.4 4652.5 6140.8 4706.4 3928.98 6056.8 4865.4 FALSE FALSE TRUE 4943.209221 4783.358414 5304.670106 5436.810449 4597.021976 4867.128859 4838.448917 5126.907915 5392.384193 5034.472288 0.981872367 0.950121113 1.053669541 1.07991665 0.913109004 0.966760483 0.96106377 1.01836054 1.071092239 1 12.29762485 ATEGMVVADKNCSK ddPTM_HeLa_Curcumin_4h_R1 1 ATEGMVVADKNCSK 14 1 Q99436;Q5TBG5;Q99436-2 Q99436 PSMB7 Proteasome subunit beta type-7;Proteasome subunit beta type 0 0 81.632 0.014169 2641100 718.38 496.95 613.6 581.98 569.89 934.84 532.47 684.01 778.51 759.16 FALSE FALSE TRUE 661.519465 539.9041436 636.3405558 579.571921 563.094434 740.9436462 547.4096751 892.5615002 693.1094007 785.5407535 0.842119854 0.687302525 0.810066891 0.73779994 0.71682396 0.943227507 0.69685713 1.136238313 0.882334109 1 9.617542314 -8.688436569 0.899376366 0.987885835 0.812228934 0.091146832 0.133416511 0.554959995 0.899862584 0.052804883 0.024527573 2.05E-09 8.688436569 -0.175656901 ATEMVEVGADDDEGGAERGEAGDLRR ddPTM_HeLa_Curcumin_4h_R1 2 ATEMVEVGADDDEGGAERGEAGDLRR 26 2 Q6NZI2;Q6NZI2-3;Q6NZI2-2 Q6NZI2 PTRF Polymerase I and transcript release factor 0 0 ; ; 70.358 0.00022076 18544300 9782.9 7301.1 7194.5 7496.7 7151.3 9476.3 6626.1 4841.2 10322.4 8283.7 FALSE FALSE TRUE 9008.573142 7932.174551 7461.134499 7465.680642 7066.025418 7510.80856 6812.010533 6317.259594 9190.058545 8571.557958 1.050984335 0.925406395 0.870452552 0.870982927 0.824357188 0.876247772 0.794722566 0.737002494 1.072157313 1 13.06534174 -6.803735524 1.430279968 1.024703923 0.819442553 0.837230908 0.042059696 0.113660048 0.468337106 0.007704366 0.011160225 1.57E-07 6.803735524 -0.205261369 S(ph)QSAAVT(ph)PSSTTSSTR ddPTM_HeLa_Curcumin_4h_R1 1 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 2 0 S(0.939)QS(0.419)AAVT(0.431)PS(0.105)S(0.08)T(0.013)T(0.01)S(0.003)S(0.001)T(0.001)R 102.79 0.0098309 5350300 1861.8 1844.8 2071 1891.6 2045 3490.5 3151 2785.3 2215 1631.4 TRUE FALSE FALSE 1714.436565 2004.256292 2147.753082 1883.77306 2020.614711 2766.530954 3239.40858 3634.525148 1972.020042 1688.091029 1.015606704 1.187291596 1.272296959 1.115919123 1.19698208 1.63885176 1.918977428 2.153038602 1.168195321 1 10.72117699 -4.428306724 0.603886803 1.016600808 2.841580918 0.929693681 0.100175334 0.429756683 0.120067525 0.017252343 0.521725204 3.73E-05 4.428306724 1.82498011 up ATETT(ph)DEDEDGGSEKK ddPTM_HeLa_Curcumin_4h_R1 1 ATETTDEDEDGGSEKK 16 1 H0Y6H0;Q8NB78;Q8NB78-2 H0Y6H0 KDM1B Lysine-specific histone demethylase 1B 1 0 AT(0.017)ET(0.167)T(0.816)DEDEDGGSEKK 70.334 0.012924 6630600 2785.3 2152.9 2564.2 2220.9 2222.3 2963.8 2100.5 1205.5 2421.2 2374.2 TRUE FALSE FALSE 2564.840566 2338.987083 2659.231508 2211.710504 2195.800524 2349.074471 2159.434377 1573.051401 2155.600418 2456.703273 1.044017238 0.952083676 1.08243903 0.9002758 0.893799649 0.956189743 0.878996825 0.640309889 0.877436213 1 11.2625079 -3.472168174 0.603511865 1.015372046 1.62E-16 0.630074539 0.070204846 2.524236001 0.317792115 0.009717141 2.221245668 0.000337157 3.472168174 -1.015372046 ATEVSK(ac)TPEAR ddPTM_HeLa_Curcumin_4h_R1 1 ATEVSKTPEAR 11 1 Q5H909;Q9UNF1-2;Q9UNF1 Q5H909 MAGED2 Melanoma-associated antigen D2 0 1 ATEVSK(1)TPEAR 112.83 0.0036029 2783900 520.46 503.55 303.78 390.57 407.65 407.13 520.58 364.84 553.18 554.17 FALSE TRUE FALSE 479.2650418 547.0746182 315.038354 388.9539248 402.78904 322.6866487 535.1860737 476.0780365 492.497538 573.4273663 0.83579032 0.954043442 0.549395394 0.67829676 0.702423818 0.562733256 0.933311009 0.830232501 0.85886647 1 9.163466947 -7.840242236 0.694584247 0.973604304 0.724652126 0.253179425 0.130972688 0.475918844 0.512152628 0.045170196 0.035538162 1.44E-08 7.840242236 -0.248952178 ATFIKVPQNQNGK ddPTM_HeLa_Curcumin_4h_R1 2 ATFIKVPQNQNGK 13 1 P19338;H7BY16 P19338 NCL Nucleolin 0 0 ; ; 85.672 0.013102 7349400 5809.4 3675 3960.4 4329.3 3572.6 5727.2 3884.5 4725.7 5987.3 5219.1 FALSE FALSE TRUE 5349.57986 3992.650625 4107.175908 4311.386504 3529.999078 4539.314161 3993.488615 6166.544176 5330.508169 5400.463337 0.990577942 0.73931631 0.760522876 0.798336408 0.653647448 0.840541613 0.73947148 1.14185465 0.987046451 1 12.39886747 -7.274619199 23.28529727 0.995550715 0.80052278 0.316201978 0.122014932 233.6040468 412716.4005 0.019421351 0.022293293 5.31E-08 7.274619199 -0.195027935 DDS(ph)EKLLLCSRS(ph)S(ph)VESQVT(ph)FK ddPTM_HeLa_Curcumin_4h_R1 1 DDSEKLLLCSRSSVESQVTFK 21 2 A0A0A0MR64;Q3SXY7-2;Q3SXY7 A0A0A0MR64 LRIT3 "Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3" 4 0 DDS(0.998)EKLLLCS(0.593)RS(0.613)S(0.613)VES(0.198)QVT(0.985)FK 45.125 0.020083 126760000 2025.7 1692.3 1790.1 2159.5 2187.6 1937.6 942.49 689.23 2479.2 2055.2 TRUE FALSE FALSE 1865.363707 1838.574871 1856.442681 2150.564561 2161.514299 1535.719919 968.9337328 899.3730542 2207.237963 2126.618047 0.877150323 0.864553404 0.872955387 1.011260374 1.016409271 0.722141863 0.455621889 0.422912359 1.037909918 1 11.05434522 -4.922989635 2.763004766 0.938692002 0.427965375 0.911216652 0.064077709 0.057143025 0.866862704 0.009758374 0.036209318 1.19E-05 4.922989635 -0.510726627 down QNSTSLT(ph)GKPGALPANLDDMK ddPTM_HeLa_Curcumin_4h_R1 1 QNSTSLTGKPGALPANLDDMK 21 1 E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;W0Z7M9;B0QY83;A0A499FIJ6;Q969V6 E7ER32 MKL1 MKL/myocardin-like protein 1 1 0 QNS(0.064)T(0.064)S(0.337)LT(0.536)GKPGALPANLDDMK 113.89 1.54E-05 33076000 1418.8 972.39 1371.3 1640.6 1370 1656 2048.2 2310.3 1089.9 1366.6 TRUE FALSE FALSE 1306.500483 1056.439059 1422.121584 1633.811632 1353.663645 1312.526933 2105.66698 3014.699835 970.3406968 1414.089248 0.923916566 0.747080893 1.005680219 1.155380846 0.95726889 0.928178285 1.489062294 2.131902098 0.686194806 1 10.46565746 -4.425907588 2.14038947 0.96024783 2.253201376 0.891104397 0.132605625 0.085068009 0.555186724 0.014698383 0.183151759 3.75E-05 4.425907588 1.292953546 up ATGDETGAK(ac)VER ddPTM_HeLa_Curcumin_4h_R1 1 ATGDETGAKVER 12 1 P61247;H0Y9Y4;D6RAT0;D6R9B6 P61247 RPS3A 40S ribosomal protein S3a 0 1 ATGDETGAK(1)VER 134.38 0.00030824 1563900 608.46 456.2 458.99 325.16 502.48 432.76 259.32 516.51 523.02 488.61 FALSE TRUE FALSE 560.299749 495.6318952 476.0005732 323.8145741 496.4882542 343.0006978 266.5958213 673.9915213 465.6460145 505.5891611 1.108211552 0.980305618 0.941477013 0.640469771 0.981999403 0.678417823 0.527297343 1.333081429 0.92099683 1 8.981821725 -6.650267626 2.747761716 1.049095562 0.813972054 0.104229594 0.21381162 0.298169754 4.571729847 0.031510304 0.04589648 2.24E-07 6.650267626 -0.235123508 EQDVVTGVS(ph)PLLFR ddPTM_HeLa_Curcumin_4h_R1 3 EQDVVTGVSPLLFR 14 0 Q6P0Q8;Q6P0Q8-2 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 0 EQDVVT(0.486)GVS(0.514)PLLFR;EQDVVT(0.001)GVS(0.999)PLLFR;EQDVVT(0.02)GVS(0.98)PLLFR ;; 154.51 0.0004118 48742700 7317.3 5269.59 6369.09 6314.44 6915.2 4561.51 2639.07 859.974 5613.87 4923.55 TRUE FALSE FALSE 6738.127984 5725.069879 6605.134078 6288.31252 6832.740756 3615.401407 2713.115202 1122.176114 4998.042506 5094.642996 1.322590805 1.123743093 1.296486149 1.234298954 1.341161836 0.709647646 0.532542752 0.220265898 0.981038811 1 12.31476534 -4.918641971 2.082959125 1.181395329 0.312903307 0.850704209 0.138457438 0.097134192 0.809358602 0.021902315 0.096712798 1.21E-05 4.918641971 -0.868492022 down LDS(ph)DFNISSHS(ph)ELENSSELK ddPTM_HeLa_Curcumin_4h_R1 1 LDSDFNISSHSELENSSELK 20 0 E9PHV5;P28290-3;P28290;P28290-2 E9PHV5 SSFA2 Sperm-specific antigen 2 2 0 LDS(0.605)DFNIS(0.261)S(0.137)HS(0.994)ELENS(0.002)S(0.001)ELK 74.748 0.0096697 2996700 1980.3 1826.4 1859.6 1633.6 1586.4 1651.3 750.29 543.73 1647 1403.7 TRUE FALSE FALSE 1823.557165 1984.265878 1928.518412 1626.840596 1567.483216 1308.801766 771.3411181 709.510774 1466.328221 1452.478471 1.255479652 1.366124124 1.3277432 1.120044551 1.079178279 0.901081698 0.53105167 0.488482816 1.009535253 1 10.50430106 -4.915984872 1.694780072 1.159627609 0.452685593 0.836479548 0.115670845 0.143566814 0.74971536 0.02079927 0.109153267 1.21E-05 4.915984872 -0.706942016 down ATGEGGASDLPEDPDEDAIPIT ddPTM_HeLa_Curcumin_4h_R1 1 ATGEGGASDLPEDPDEDAIPIT 22 0 O15541 O15541 RNF113A RING finger protein 113A 0 0 117.03 7.30E-05 4393300 2160.2 1717.1 1646.1 1708.1 1621.5 2194.4 1331.5 1719.3 1649.6 1898.5 FALSE FALSE TRUE 1989.217891 1865.518473 1707.105914 1701.032335 1602.164672 1739.256704 1368.858306 2243.506655 1468.643007 1964.472734 1.012596335 0.949628081 0.868989365 0.865897656 0.815569819 0.885355482 0.696806977 1.142040109 0.747601625 1 10.93992643 -6.934223904 2.664101556 1.00586157 0.866860728 0 0.132108745 0.245202808 3.537922573 0.0155864 0.020730586 1.16E-07 6.934223904 -0.139000843 SQS(ph)LPNSLDYTQTSDPGR ddPTM_HeLa_Curcumin_4h_R1 2 SQSLPNSLDYTQTSDPGR 18 0 H0YNE5;H0YLG5;Q96TC7 H0YNE5 RMDN3 Regulator of microtubule dynamics protein 3 1 0 S(0.003)QS(0.992)LPNS(0.005)LDYTQTSDPGR;S(0.008)QS(0.989)LPNS(0.002)LDYTQTSDPGR ; 290.88 2.27E-81 46081000 3199.1 1769.33 2547.2 2773.8 2709.3 2179.1 994.6 423.55 3229 2640.7 TRUE FALSE FALSE 2945.887859 1922.263001 2641.601473 2762.322751 2676.993367 1727.130096 1022.505799 552.6884452 2874.786779 2732.464128 1.078106691 0.703490663 0.96674699 1.010927361 0.979699363 0.632077866 0.374206486 0.202267411 1.052085826 1 11.41598684 -4.914310687 1.563094019 1.005600324 0.199136306 0.87783333 0.102594142 0.108525321 0.467519064 0.016111374 0.091449644 1.22E-05 4.914310687 -0.806464018 down ATGPEAAGGGGAGGGGGGYRPIIQS(ph)PGYK ddPTM_HeLa_Curcumin_4h_R1 2 ATGPEAAGGGGAGGGGGGYRPIIQSPGYK 29 1 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 0 ATGPEAAGGGGAGGGGGGY(0.333)RPIIQS(0.665)PGY(0.002)K;AT(0.002)GPEAAGGGGAGGGGGGY(0.024)RPIIQS(0.97)PGY(0.003)K ; 53.147 0.0028154 29789000 2677.17 1774.13 2144.85 2428.18 2012.28 2756.6 1901.24 865.5 2347.75 1951.84 TRUE FALSE FALSE 2465.26917 1927.477892 2224.340028 2418.132835 1988.284875 2184.850087 1954.583677 1129.386966 2090.207699 2019.666295 1.220631931 0.954354636 1.101340372 1.197293256 0.984462077 1.081787666 0.967775559 0.559194838 1.034927257 1 10.97990122 -3.998015249 1.494177315 1.094800999 0.011219943 0.765354932 0.084238421 0.879228206 1.078955808 0.014210874 1.694587666 0.000100458 3.998015249 -1.083581056 ATILDIIK ddPTM_HeLa_Curcumin_4h_R1 1 ATILDIIK 8 0 H7C3J1;Q6SA08-3;Q6SA08;Q6SA08-2 H7C3J1 TSSK4 Testis-specific serine/threonine-protein kinase 4 0 0 99.375 0.013989 6235000 4784.9 6779.4 5516.9 8438.2 5984.8 3479.9 3024.3 1686.5 3524 4234.8 FALSE FALSE TRUE 4406.170116 7365.381128 5721.361167 8403.284964 5913.435169 2758.129513 3109.153719 2200.706086 3137.426017 4381.958985 1.005525184 1.680842097 1.305662875 1.917700506 1.349495782 0.629428418 0.709535103 0.502219691 0.71598708 1 12.09736027 -5.24822629 23.50451952 1.168553122 0.623308304 0.422820541 0.340167671 333.4899452 593235.1716 0.05174215 0.130901777 5.65E-06 5.24822629 -0.545244818 ATIS(ph)DEEIER ddPTM_HeLa_Curcumin_4h_R1 4 ATISDEEIER 10 0 Q9UQN3-2;Q9UQN3;C9J0A7 Q9UQN3-2 CHMP2B Charged multivesicular body protein 2b 1 0 AT(0.028)IS(0.972)DEEIER;AT(0.247)IS(0.753)DEEIER;AT(0.113)IS(0.887)DEEIER;AT(0.019)IS(0.981)DEEIER ;;; 182.41 0.00026002 1966179700 7025.6 5723.4 6067.4 7304 6281.2 7505.5 5590.38 5083.34 6826.7 6374.4 TRUE FALSE FALSE 6469.516347 6218.105193 6292.263181 7273.777983 6206.300792 5948.774696 5747.231017 6633.226965 6077.82809 6595.909926 0.980837583 0.942721363 0.953964389 1.102770969 0.940931708 0.901888407 0.87133255 1.005657603 0.921454077 1 12.68735598 -5.539092758 24.99993533 0.991876701 0.920898992 0.173672211 0.055946923 211.8499625 326644.972 0.007045259 0.014093383 2.89E-06 5.539092758 -0.070977709 ATIS(ph)SPLELEGTVSR ddPTM_HeLa_Curcumin_4h_R1 2 ATISSPLELEGTVSR 15 0 Q96GS4 Q96GS4 C17orf59 Uncharacterized protein C17orf59 1 0 ATIS(0.624)S(0.376)PLELEGTVSR;AT(0.002)IS(0.931)S(0.067)PLELEGTVSR ; 162.67 0.00027698 10316100 6644.9 5866.4 6292.6 7154.1 6975.9 8955.3 7285.8 6537.7 7392.6 5970.5 TRUE FALSE FALSE 6118.949153 6373.465476 6525.809292 7124.49823 6892.716949 7097.869833 7490.219939 8531.014634 6581.650275 6177.974431 0.990445853 1.031643227 1.056302412 1.153209407 1.115692049 1.148899192 1.21240708 1.380875679 1.065341132 1 12.59291818 -1 0.310142976 0.985869717 4.469977177 0.883352496 0.038090758 8.491677749 0.108536811 0.011423109 16.83433884 0.1 1 3.48410746 ATISNDGATILK ddPTM_HeLa_Curcumin_4h_R1 2 ATISNDGATILK 12 0 Q99832-3;Q99832;F8WAM2 Q99832-3 CCT7 T-complex protein 1 subunit eta 0 0 ; ; 192.44 5.05E-14 14328800 4991.7 4325.1 5012.2 4971.2 4915.9 3437.5 4074.9 4084.8 5212.8 4721.9 FALSE FALSE TRUE 4596.601678 4698.942372 5197.956541 4950.630492 4857.281103 2724.523751 4189.230727 5330.236716 4640.968882 4885.985674 0.940772648 0.96171841 1.06385014 1.013230661 0.994125122 0.557620086 0.85739726 1.090923525 0.94985315 1 12.25443392 ATLDEEDLVDS(ph)LSEGDAYPNGLQVNFHSPR ddPTM_HeLa_Curcumin_4h_R1 1 ATLDEEDLVDSLSEGDAYPNGLQVNFHSPR 30 0 E9PN99;E9PHZ1;B4DKB2;A0A3B3ISF9;P42892-3;P42892-4;P42892 E9PN99 ECE1 Endothelin-converting enzyme 1 1 0 ATLDEEDLVDS(0.415)LS(0.415)EGDAY(0.169)PNGLQVNFHS(0.001)PR 56.854 0.0012453 3014900 604.82 554.41 703.23 839.24 738.59 1113 405.88 158.07 1106 902.95 TRUE FALSE FALSE 556.9478588 602.33073 729.2923224 835.7674472 729.7827966 882.1512539 417.2679004 206.2648153 984.6745671 934.3274453 0.596094936 0.644667705 0.780553248 0.894512359 0.781078197 0.944156418 0.446597071 0.220762877 1.05388595 1 9.867784437 -4.586637639 4.308938544 0.802425564 0.263322055 0.671550105 0.142743263 0.101476493 3.657356469 0.023020856 0.100941552 2.59E-05 4.586637639 -0.539103509 ATLDEEDLVDSLS(ph)EGDAYPNGLQVNFHSPR ddPTM_HeLa_Curcumin_4h_R1 1 ATLDEEDLVDSLSEGDAYPNGLQVNFHSPR 30 0 E9PN99;E9PHZ1;B4DKB2;A0A3B3ISF9;P42892-3;P42892-4;P42892 E9PN99 ECE1 Endothelin-converting enzyme 1 1 0 ATLDEEDLVDS(0.184)LS(0.805)EGDAY(0.011)PNGLQVNFHSPR 86.304 1.24E-06 5652900 972.01 1051.3 1329.8 1432 1049.5 1833.1 705.42 221.01 1991.4 1397.8 TRUE FALSE FALSE 895.0743828 1142.169687 1379.083558 1426.074763 1036.985398 1452.894397 725.2121867 288.3949316 1772.948402 1446.373446 0.618840442 0.789678275 0.953476823 0.985965808 0.716955501 1.004508483 0.501400374 0.199391749 1.225788822 1 10.49822438 -4.534366823 3.834708165 0.837789422 0.240032151 0.616832082 0.176277574 0.10365299 3.265782653 0.022729858 0.119358101 2.92E-05 4.534366823 -0.597757271 ATLEVILRPK ddPTM_HeLa_Curcumin_4h_R1 1 ATLEVILRPK 10 1 M0R102;Q9NQT4 M0R102 EXOSC5 Exosome complex component RRP46 0 0 93.096 0.0015141 0 624.01 628.69 594.94 487.49 588.8 619.5 562.65 519.28 570.77 687.21 FALSE FALSE TRUE 574.61895 683.0311622 616.9889998 485.4728955 581.7789446 491.0087168 578.4364447 677.6060815 508.157959 711.0904963 0.808081324 0.960540417 0.867665934 0.682716051 0.818150359 0.690501025 0.813449832 0.952911177 0.714617846 1 9.473889365 -6.511301192 23.31370904 0.910840282 0.787283413 0.076100849 0.104332821 238.04757 479356.0973 0.015213254 0.022440673 3.08E-07 6.511301192 -0.123556869 ATLLAPDT(ph)GET(ph)T(ph)T(ph)LPPGR ddPTM_HeLa_Curcumin_4h_R1 1 ATLLAPDTGETTTLPPGR 18 0 Q8TBH0 Q8TBH0 ARRDC2 Arrestin domain-containing protein 2 4 0 AT(0.062)LLAPDT(0.941)GET(0.999)T(0.999)T(0.999)LPPGR 51.695 0.0083262 0 2533.2 731.12 495.87 724.24 1547.3 4119.6 1307.2 962.58 839.91 494.77 TRUE FALSE FALSE 2332.694547 794.314755 514.2473784 721.2432868 1528.849458 3265.148523 1343.876514 1256.066211 747.7739744 511.9632207 4.556371342 1.551507458 1.004461566 1.408779494 2.986248614 6.377701348 2.624947378 2.453430559 1.460600965 1 8.999896361 -9.650461299 1.493963856 1.002402092 3.092812131 0.142571085 1.526000854 0.575633947 2.314728296 1.182517462 0.268396159 2.24E-10 9.650461299 2.09041004 ATLLEDQQDPS(ph)PSS ddPTM_HeLa_Curcumin_4h_R1 1 ATLLEDQQDPSPSS 14 0 B5MBZ0;Q9HC35;Q9HC35-2 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 0 ATLLEDQQDPS(0.922)PS(0.064)S(0.014) 109.83 0.0029967 6166500 3417.6 3173.1 3274.6 3197.7 3324.2 4648.6 3479.5 3413.4 4127.9 3581.3 TRUE FALSE FALSE 3147.093354 3447.368625 3395.959557 3184.468765 3284.561086 3684.427959 3577.125405 4454.129947 3675.079697 3705.749908 0.849246018 0.930275574 0.91640279 0.859331807 0.886341811 0.994246253 0.96529056 1.201951037 0.991723616 1 11.85554981 -3.576553119 1.217995371 0.92027683 2.128403703 0.721086399 0.050918017 3.185353212 1.182945054 0.009180164 7.309469452 0.000265123 3.576553119 1.208126872 ATLLEDQQDPSPS(ph)S ddPTM_HeLa_Curcumin_4h_R1 1 ATLLEDQQDPSPSS 14 0 B5MBZ0;Q9HC35;Q9HC35-2 B5MBZ0 EML4 Echinoderm microtubule-associated protein-like 4 1 0 ATLLEDQQDPS(0.1)PS(0.56)S(0.34) 146.67 0.00059755 6267200 1929.6 2139.3 2014.8 2164.2 2074.7 2657.9 2023.9 1992.5 2505.9 1982.4 TRUE FALSE FALSE 1776.870124 2324.211559 2089.47026 2155.245114 2049.960558 2106.621579 2080.685187 2600.004078 2231.009039 2051.288252 0.866221567 1.13304971 1.018613673 1.050678817 0.999352751 1.026974915 1.014330962 1.267498156 1.087613619 1 11.00231452 -7.261250067 24.99996103 0.936826851 1.063132618 0.091206256 0.093946885 15.27437599 2017099.553 0.014438177 0.01709231 5.48E-08 7.261250067 0.126305766 ATLPDADKER ddPTM_HeLa_Curcumin_4h_R1 1 ATLPDADKER 10 1 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8 P12814-4 ACTN1 Alpha-actinin-1 0 0 94.409 0.014045 6605300 4621.3 3177.8 4548.9 3717.7 4342.6 5353.3 4138.8 4766.8 3946.4 3634.4 FALSE FALSE TRUE 4255.519229 3452.474872 4717.486236 3702.317142 4290.817331 4242.965236 4254.923589 6220.175376 3513.489793 3760.695129 1.131577829 0.918041679 1.254418684 0.984476809 1.140963887 1.128239618 1.131419443 1.653996179 0.934266053 1 11.87678364 ATLPS(ph)PDKLPGFK ddPTM_HeLa_Curcumin_4h_R1 2 ATLPSPDKLPGFK 13 1 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 1 0 AT(0.008)LPS(0.992)PDKLPGFK;ATLPS(1)PDKLPGFK ; 72.523 0.014027 199237000 6995.3 5951.3 6156.7 6326 6231.9 7460.4 5761.9 6096 6357.3 5530.3 TRUE FALSE FALSE 6441.614624 6465.703854 6384.872718 6299.824688 6157.588663 5913.028944 5923.563407 7954.642337 5659.920095 5722.477513 1.12566884 1.12987842 1.115753221 1.100891122 1.076035449 1.033298764 1.035139656 1.390069654 0.989068123 1 12.48242417 -13.52287875 0.223857452 0.352509639 1.135511282 0.245654007 0.094136619 59.85386055 0.763355808 16.98251058 0.070408724 3.00E-14 13.52287875 0.783001643 ATLPSPDK(ac)LPGFK ddPTM_HeLa_Curcumin_4h_R1 1 ATLPSPDKLPGFK 13 1 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 1 ATLPSPDK(1)LPGFK 154.28 0.00013491 1498600 599.74 822.42 712.94 620.76 1082.6 1860.4 1109.6 1095.8 1938.5 682.96 FALSE TRUE FALSE 552.2699462 893.5063202 739.3621836 618.1914596 1069.690702 1474.532069 1140.73239 1429.904376 1725.8514 706.6928092 0.781485164 1.264348963 1.046228537 0.874766874 1.513657261 2.086524795 1.614184232 2.023374735 2.442152202 1 9.464939419 -5.598902016 3.45349219 0.935912793 1.875183563 0.122980874 0.506481461 0.062546058 1.491329992 0.026200343 0.056118075 2.52E-06 5.598902016 0.939270771 ATLPSPDKLPGFK ddPTM_HeLa_Curcumin_4h_R1 1 ATLPSPDKLPGFK 13 1 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 0 93.345 0.0071772 2960100 2212.4 2102.4 2028.9 2000.9 2084.8 2681.7 1811.6 1983.1 2162.9 2096.7 FALSE FALSE TRUE 2037.286205 2284.122088 2104.092819 1992.620806 2059.940122 2125.485191 1862.42862 2587.738061 1925.635281 2169.560169 0.939031899 1.052804214 0.969824598 0.918444593 0.949473608 0.979684833 0.858436031 1.192747773 0.887569429 1 11.08318688 -4.243190383 24.53781905 0.965980162 1.192748024 0.629009686 0.054654056 1443.588226 1941028.159 0.006639035 0.287386739 5.71E-05 4.243190383 0.226767861 ATLSSTSGLDLMS(ph)ESGEGEISPQR ddPTM_HeLa_Curcumin_4h_R1 1 ATLSSTSGLDLMSESGEGEISPQR 24 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424;H0YDG6 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 ATLS(0.004)S(0.003)T(0.013)S(0.018)GLDLMS(0.837)ES(0.029)GEGEIS(0.095)PQR 74.047 0.00037929 0 1147.9 1100.4 1443.5 1228.9 1600 1299 1150.3 1446.7 1284.9 992.29 TRUE FALSE FALSE 1057.042504 1195.513673 1496.99738 1223.815137 1580.921045 1029.572757 1182.574322 1887.79217 1143.949685 1026.772004 1.029481229 1.164341907 1.457964742 1.191905441 1.539700186 1.002727727 1.151739936 1.838569968 1.114122396 1 10.00390015 -7.032428138 3.337633468 1.014444291 1.337944506 0.288938394 0.220647243 0.207292362 4.740025959 0.034437731 0.043983124 9.28E-08 7.032428138 0.323500215 ATLSSTSGLDLMSES(ph)GEGEISPQREVSR ddPTM_HeLa_Curcumin_4h_R1 1 ATLSSTSGLDLMSESGEGEISPQREVSR 28 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424;H0YDG6 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 ATLSSTSGLDLMS(0.154)ES(0.496)GEGEIS(0.346)PQREVS(0.003)R 71.857 0.00050626 79685000 1332 1045.4 1226.5 1275.3 1077.5 1574.6 1205.6 1337.6 1705.3 1278.1 TRUE FALSE FALSE 1226.570794 1135.759718 1271.955169 1270.023147 1064.651516 1248.010211 1239.425891 1745.428082 1518.232856 1322.51388 0.927454005 0.858788505 0.961770752 0.960309881 0.805021053 0.943665114 0.937174203 1.31978054 1.147990112 1 10.36906715 -4.260833417 24.9997205 0.943731929 1.319780655 0.630676595 0.08500106 17.71862211 730829.2434 0.008450437 0.067442533 5.48E-05 4.260833417 0.376048726 ATLSSTSGLDLMSESGEGEIS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 4 ATLSSTSGLDLMSESGEGEISPQR 24 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424;H0YDG6 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 ATLSSTSGLDLMS(0.006)ES(0.029)GEGEIS(0.965)PQR;ATLSSTSGLDLMSESGEGEIS(1)PQR;ATLS(0.001)S(0.001)T(0.001)S(0.005)GLDLMS(0.385)ES(0.025)GEGEIS(0.581)PQR;ATLSSTSGLDLMSES(0.002)GEGEIS(0.998)PQR ;;; 184.31 1.28E-11 45792300 6331.4 6217.5 6276.3 7351.1 7083.1 7762.2 5883.5 6049.8 6337.8 5533.3 TRUE FALSE FALSE 5830.263009 6754.912995 6508.905199 7320.683096 6998.638659 6152.232222 6048.575175 7894.35617 5642.559196 5725.581763 1.018283076 1.17977758 1.136811152 1.27859201 1.222345422 1.074516525 1.056412331 1.378786732 0.985499715 1 12.48320657 -7.270557483 4.457041507 1.007822852 1.183528259 0.482756669 0.089158477 0.131205272 6.77107766 0.014704682 0.017300303 5.36E-08 7.270557483 0.175705407 ATLSSTSGLDLMSESGEGEIS(ph)PQREVSR ddPTM_HeLa_Curcumin_4h_R1 3 ATLSSTSGLDLMSESGEGEISPQREVSR 28 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424;H0YDG6 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 ATLSSTSGLDLMS(0.011)ES(0.043)GEGEIS(0.942)PQREVS(0.003)R;ATLSST(0.001)S(0.002)GLDLMS(0.157)ES(0.157)GEGEIS(0.642)PQREVS(0.042)R;ATLSSTSGLDLMSES(0.001)GEGEIS(0.992)PQREVS(0.006)R ;; 121.24 8.55E-11 276264000 3265.64 2821.14 2840.28 2829.55 2403.11 3475.21 2588.9 2833.21 3648.63 3179.31 TRUE FALSE FALSE 3007.161148 3064.986771 2945.543275 2817.842072 2374.454483 2754.412272 2661.537566 3697.042687 3248.384417 3289.790786 0.914088872 0.931666167 0.895358844 0.85654142 0.721764585 0.83726062 0.809029431 1.123792644 0.987413677 1 11.68378012 -8.00884764 0.58968388 0.992222695 0.864086929 0.167880104 0.097492535 0.853186201 0.681936326 0.044543601 0.028681926 9.80E-09 8.00884764 -0.128135766 ATLTAS(ph)PLGAS ddPTM_HeLa_Curcumin_4h_R1 1 ATLTASPLGAS 11 0 Q13111;Q13111-3 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 0 ATLT(0.012)AS(0.957)PLGAS(0.031) 88.596 0.018936 21977000 7673.6 5913 6391.1 7294.3 6811.4 8289.7 6006 3913.2 7367.4 6696.6 TRUE FALSE FALSE 7066.226463 6424.093372 6627.959788 7264.118119 6730.178504 6570.322776 6174.512196 5106.316666 6559.214652 6929.306352 1.01975957 0.927090396 0.956511294 1.048318223 0.971262946 0.948193433 0.891072191 0.736915992 0.946590368 1 12.75849523 -3.455370601 0.811822001 1.001832353 1.55E-17 0.793422295 0.037105719 2.009318231 0.374435456 0.005418037 2.477905176 0.000350453 3.455370601 -1.001832353 ATLYVTAIEDR ddPTM_HeLa_Curcumin_4h_R1 1 ATLYVTAIEDR 11 0 E9PNR9;E9PQ98;E9PIX6;H0YDE4;E9PKG1;Q99873-2;Q99873-3;Q99873 E9PNR9 PRMT1 Protein arginine N-methyltransferase 1 0 0 139.43 0.012206 2735200 1068.9 1251.6 799.12 1051.1 1198.5 1208.1 1061.1 794.64 1387.6 1045.6 FALSE FALSE TRUE 984.2954371 1359.782727 828.7360902 1046.750827 1184.20867 957.5264419 1090.87161 1036.922078 1235.383752 1081.934522 0.909755089 1.256806858 0.765976197 0.967480753 1.094528963 0.8850133 1.008260285 0.958396332 1.141828573 1 10.07939748 ATMAQNENVVVQPVVAENIPVIPLSDSPPPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 ATMAQNENVVVQPVVAENIPVIPLSDSPPPSR 32 0 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 0 ATMAQNENVVVQPVVAENIPVIPLS(0.094)DS(0.417)PPPS(0.489)R;ATMAQNENVVVQPVVAENIPVIPLS(0.052)DS(0.147)PPPS(0.801)R ; 71.878 2.35E-05 53936000 1546.3 1515.26 1463.66 1963.73 1313.52 2142.78 1712.81 1387.77 2049.18 1554.7 TRUE FALSE FALSE 1423.908723 1646.232323 1517.904527 1955.604606 1297.857132 1698.343274 1760.866839 1810.894684 1824.390081 1608.725709 0.885115912 1.023314486 0.943544644 1.215623393 0.806760981 1.055707175 1.094572449 1.125670258 1.134059132 1 10.65170265 ATNES(ph)EDEIPQLVPIGK ddPTM_HeLa_Curcumin_4h_R1 9 ATNESEDEIPQLVPIGK 17 0 O76021;O76021-2;J3QSV6 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 0 AT(0.009)NES(0.991)EDEIPQLVPIGK;AT(0.006)NES(0.994)EDEIPQLVPIGK;AT(0.012)NES(0.988)EDEIPQLVPIGK;AT(0.005)NES(0.995)EDEIPQLVPIGK;AT(0.297)NES(0.703)EDEIPQLVPIGK;AT(0.072)NES(0.928)EDEIPQLVPIGK;AT(0.002)NES(0.998)EDEIPQLVPIGK;AT(0.049)NES(0.951)EDEIPQLVPIGK;AT(0.075)NES(0.925)EDEIPQLVPIGK ;;;;;;;; 145.91 0.00027536 3839989800 51947 47780.6 50316.7 53444.2 47480.6 58075 40140 31063.2 54971.5 45781.7 TRUE FALSE FALSE 47835.34014 51910.54216 52181.48117 53223.06206 46914.42486 46029.59036 41266.22037 40534.22668 48941.26398 47372.61067 1.009767869 1.095792303 1.101511621 1.123498606 0.990328044 0.971649857 0.871098717 0.855646884 1.033113086 1 15.53176556 -4.886181938 1.997512886 1.027633462 0.851839179 0.708231916 0.046466118 0.18827503 1.424317708 0.008049143 0.038380291 1.30E-05 4.886181938 -0.175794283 ATNES(ph)EDEIPQLVPIGKK ddPTM_HeLa_Curcumin_4h_R1 2 ATNESEDEIPQLVPIGKK 18 1 O76021;O76021-2;J3QSV6 O76021 RSL1D1 Ribosomal L1 domain-containing protein 1 1 0 AT(0.029)NES(0.971)EDEIPQLVPIGKK;AT(0.287)NES(0.713)EDEIPQLVPIGKK ; 125.04 0.00011775 1153520000 5835.4 4360.7 3996.5 5167 3357.2 5785.8 3483.2 2885.8 7710.7 5579.3 TRUE FALSE FALSE 5373.521933 4737.619477 4144.613806 5145.620323 3317.167583 4585.759861 3580.929217 3765.667135 6864.855501 5773.18026 0.930773281 0.820625594 0.717908262 0.89129736 0.574582368 0.794321267 0.620269774 0.652269107 1.189094259 1 12.49515056 -6.724158878 0.491345882 0.99826646 0.639007998 0.69137659 0.100199697 0.324179397 0.170074334 0.024105011 0.045641989 1.89E-07 6.724158878 -0.359258462 ATPATAPGTS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 ATPATAPGTSPR 12 0 Q96P47;Q96P47-2;Q96P47-4;H0Y873;Q96P47-5 Q96P47 AGAP3 "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3" 1 0 ATPATAPGT(0.313)S(0.687)PR;ATPATAPGT(0.122)S(0.878)PR ; 104.81 0.0071241 162177000 8369.9 6866.4 7640.4 7703.6 7540.5 10158.6 6099 3429.2 8947 7077 TRUE FALSE FALSE 7707.413583 7459.90102 7923.559945 7671.724544 7450.584462 8051.591849 6270.121525 4474.747294 7965.536484 7322.925223 1.05250475 1.018705066 1.082021146 1.047631146 1.01743282 1.099504857 0.856231811 0.611060083 1.087753356 1 12.83820435 -4.425541143 2.726078441 1.033889089 0.594112146 0.930045206 0.037435832 0.056977329 0.679229785 0.00495738 0.046604215 3.75E-05 4.425541143 -0.439776943 T(ph)SPDPSPVSAAPSK ddPTM_HeLa_Curcumin_4h_R1 4 TSPDPSPVSAAPSK 14 0 Q13469-5;Q13469-3;Q13469-4;Q13469-2;Q13469 Q13469-5 NFATC2 "Nuclear factor of activated T-cells, cytoplasmic 2" 1 0 T(0.6)S(0.4)PDPSPVSAAPSK;T(0.918)S(0.082)PDPSPVSAAPSK;T(0.984)S(0.016)PDPSPVSAAPSK;T(0.5)S(0.5)PDPS(0.001)PVSAAPSK ;;; 195.94 9.01E-06 55563100 22734.5 17486.9 17203.5 18803.9 17978.9 12542.8 9414.5 4015.08 21822.3 19745.6 TRUE FALSE FALSE 20935.04034 18998.38972 17841.07684 18726.09444 17764.51336 9941.281894 9678.645532 5239.259409 19428.44829 20431.75813 1.024632349 0.929846056 0.873203213 0.916518996 0.869455935 0.486560277 0.473705957 0.256427243 0.950894591 1 14.31852573 -4.913540428 0.728884064 1.006636894 0.117579164 0.941477719 0.061640402 0.200530702 0.123906929 0.010071713 0.121607462 1.22E-05 4.913540428 -0.88905773 down ATPELGSSENSASS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 1 ATPELGSSENSASSPPR 17 0 Q9BX63 Q9BX63 BRIP1 Fanconi anemia group J protein 1 0 ATPELGS(0.001)S(0.001)ENS(0.009)AS(0.188)S(0.801)PPR 185.14 3.41E-06 23857000 2026.3 1623.5 1685.6 1697 1714.9 2345.1 1741.6 876.87 1607.6 1500.3 TRUE FALSE FALSE 1865.916217 1763.828106 1748.069819 1689.978264 1694.450938 1858.699825 1790.464609 1144.223626 1431.250302 1552.435313 1.20192848 1.136168503 1.126017815 1.088598185 1.091479254 1.197280047 1.153326386 0.737050759 0.921938769 1 10.60031744 -4.257462067 24.90274863 1.110881119 0.737050606 0.638870617 0.082031319 174.7560297 1094135.862 0.01106804 0.112490352 5.53E-05 4.257462067 -0.373830513 ATPGAPALTS(ph)MTPTAVER ddPTM_HeLa_Curcumin_4h_R1 1 ATPGAPALTSMTPTAVER 18 0 P54198-2;P54198 P54198-2 HIRA Protein HIRA 1 0 ATPGAPALT(0.085)S(0.457)MT(0.457)PT(0.001)AVER 130.4 0.00026684 16908000 2083.1 1836.2 1681.6 2341.1 2047.3 2431.8 2279.4 1366.5 2230.7 2131.2 TRUE FALSE FALSE 1918.220437 1994.912946 1743.921575 2331.413149 2022.887285 1927.417268 2343.353829 1783.139559 1985.997791 2205.259041 0.869839053 0.904616151 0.790801236 1.057206026 0.917301436 0.874009462 1.062620665 0.80858508 0.900573472 1 11.10673242 -9.498658978 1.267254506 0.999627958 0.910353708 0 0.090262882 0.714845243 2.068058458 0.054427015 0.013444698 3.17E-10 9.498658978 -0.08927425 ATQASQEY(ph) ddPTM_HeLa_Curcumin_4h_R1 1 ATQASQEY 8 0 P16104 P16104 H2AFX Histone H2AX 1 0 ATQAS(0.018)QEY(0.982) 107.59 0.0028202 47324000 4363.5 3271.3 3209.7 3127.8 3102.4 4563.3 4416.1 4944.6 3917.2 3979.9 TRUE FALSE FALSE 4018.124371 3554.056595 3328.654306 3114.857992 3065.405906 3616.820141 4540.003881 6452.185778 3487.49296 4118.201229 0.975698891 0.863011883 0.808278693 0.756363718 0.744355542 0.878252407 1.102424002 1.566748544 0.846848604 1 12.00779861 -4.312111928 2.651908412 0.927046557 1.656546182 0.813359387 0.099441448 0.16640022 1.636445149 0.017255782 0.252853418 4.87E-05 4.312111928 0.729499625 AGK(ac)NQGDPK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AGKNQGDPKK 10 2 P19338 P19338 NCL Nucleolin 0 2 ; AGK(1)NQGDPK(1)K;AGK(1)NQGDPK(1)K 198.72 6.60E-26 4743400 7983.7 6481.4 6987.6 6642.5 7085.3 10288.7 12214.2 15645.8 7894.5 6867.2 FALSE TRUE FALSE 7351.781721 7041.623335 7246.566603 6615.015095 7000.812425 8154.707642 12556.89758 20416.1324 7028.493101 7105.834689 1.034611983 0.990963573 1.019805121 0.930927243 0.985220278 1.147607283 1.767124923 2.873150487 0.989115763 1 12.79478841 -4.311410616 1.604925792 1.004856877 3.451844612 0.996639113 0.033683295 0.04128086 0.107277992 0.005772842 0.152209635 4.88E-05 4.311410616 2.446987735 up SVSSNVASVSPIPAGSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 SVSSNVASVSPIPAGSKK 18 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 0 1 ; SVSSNVASVSPIPAGSK(1)K;SVSSNVASVSPIPAGSK(1)K 191.51 1.63E-12 4661100 2886.4 3650.6 3181.4 2939.7 2828.5 4605.4 4899.3 6564.3 4409.1 3836.1 FALSE TRUE FALSE 2657.938394 3966.141597 3299.305483 2927.5363 2794.771985 3650.188126 5036.761172 8565.724852 3925.432761 3969.404189 0.669606386 0.999178065 0.831184058 0.737525372 0.704078459 0.919580862 1.268896019 2.157937172 0.988922411 1 11.95470676 -4.2691023 1.810323973 0.834577072 2.582748998 0.920848108 0.116209463 0.189535221 0.624490475 0.019843512 0.560313977 5.38E-05 4.2691023 1.748171926 up ATRPASTSQPDPS(ph)PDR ddPTM_HeLa_Curcumin_4h_R1 1 ATRPASTSQPDPSPDR 16 1 P20749;H7C0A2 P20749 BCL3 B-cell lymphoma 3 protein 1 0 ATRPASTSQPDPS(1)PDR 117.07 0.010703 5004100 1041.9 1031.2 1133.8 1190.3 1276.8 1246.3 1012.1 607.85 998.96 905.67 TRUE FALSE FALSE 959.4325156 1120.332333 1175.819625 1185.374854 1261.574994 987.8033313 1040.496802 793.1806668 889.3765873 937.1419651 1.023785671 1.195477713 1.25468677 1.264882908 1.34619411 1.054059436 1.110287279 0.846382615 0.949030798 1 9.872123804 -7.302901719 7.064388603 1.01094842 1.163280883 0.236267967 0.131314603 0.270614116 38.52848978 0.022758038 0.026097393 4.98E-08 7.302901719 0.152332463 ATS(ph)DEEDSVLNIAR ddPTM_HeLa_Curcumin_4h_R1 2 ATSDEEDSVLNIAR 14 0 Q5JPF3-3;Q5JPF3 Q5JPF3-3 ANKRD36C Ankyrin repeat domain-containing protein 36C 1 0 AT(0.135)S(0.865)DEEDSVLNIAR;AT(0.092)S(0.908)DEEDSVLNIAR ; 243.49 9.22E-29 8525400 4333.4 3697.3 4189.9 4344 4228.3 4411.2 3672.49 2090.09 4306.7 4022.6 TRUE FALSE FALSE 3990.406817 4016.878137 4345.18138 4326.025679 4177.880284 3496.267396 3775.530185 2727.348819 3834.265785 4162.385051 0.958682767 0.965042419 1.043916247 1.03931415 1.003722681 0.839967315 0.907059328 0.65523703 0.921170372 1 12.02319472 -3.646350455 0.898304077 0.987993725 2.94E-15 0.786601422 0.05089865 1.718619136 0.477567685 0.00736531 2.172093085 0.000225761 3.646350455 -0.987993725 ATS(ph)DEKDSVLNIARGK ddPTM_HeLa_Curcumin_4h_R1 1 ATSDEKDSVLNIARGK 16 2 Q5JPF3-3;Q5JPF3;A6QL64 Q5JPF3-3 ANKRD36C;ANKRD36 Ankyrin repeat domain-containing protein 36C;Ankyrin repeat domain-containing protein 36A 1 0 AT(0.161)S(0.839)DEKDSVLNIARGK 57.267 0.013499 31225000 3871.7 3531 4030.7 3852.3 3567.4 3935.8 3517.2 3903.3 3455.9 3083.1 TRUE FALSE FALSE 3565.25086 3836.203906 4180.081288 3836.360203 3524.861085 3119.470714 3615.883166 5093.398201 3076.796416 3190.237496 1.117550297 1.202482233 1.31027276 1.202531225 1.104889868 0.977817708 1.133421311 1.596557688 0.96444118 1 11.63944811 -1 0.025847307 0.00651354 2.763966744 0.310552985 0.148382315 1735.655571 3.483494445 126.8855993 270.1698997 0.1 1 2.757453204 ATS(ph)FSSAGEVPKPRPPSTR ddPTM_HeLa_Curcumin_4h_R1 1 ATSFSSAGEVPKPRPPSTR 19 2 O15231-3;H7BZT5;O15231-4;O15231-7;O15231;O15231-8;O15231-6 O15231-3 ZNF185 Zinc finger protein 185 1 0 AT(0.232)S(0.697)FS(0.068)S(0.003)AGEVPKPRPPSTR 54.875 0.009008 41176000 1005.6 1045.9 1285.7 973.07 1236.3 1655 1397.1 586.96 1431.2 1358 TRUE FALSE FALSE 926.0056989 1136.302936 1333.349173 969.0436942 1221.55793 1311.734344 1436.298866 765.921402 1274.200941 1405.190399 0.658989486 0.808646954 0.948874383 0.689617361 0.869318443 0.933492248 1.022138258 0.545065923 0.906781701 1 10.45654991 -9.644952749 1.49382534 0.999444273 0.798389416 0.128938038 0.140928694 0.502079846 2.023258634 0.098845829 0.022653934 2.26E-10 9.644952749 -0.201054857 ATS(ph)PEAGGGGGALK ddPTM_HeLa_Curcumin_4h_R1 2 ATSPEAGGGGGALK 14 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 0 AT(0.011)S(0.989)PEAGGGGGALK;ATS(1)PEAGGGGGALK ; 164.22 0.00021904 104594000 10668.9 9523.9 9320.2 9501.1 9432.4 9820.4 7416.2 5338.2 10854.2 8990.1 TRUE FALSE FALSE 9824.445307 10347.10348 9665.614811 9461.786966 9319.924791 7783.538341 7624.278612 6965.792606 9663.521416 9302.505306 1.056107466 1.112292134 1.039033518 1.017122448 1.001872558 0.836714206 0.819594116 0.748808238 1.038808482 1 13.18340359 -5.185748709 1.748668704 1.035628678 0.774540381 0.922346167 0.031836487 0.08598504 0.494446881 0.005573134 0.020354435 6.52E-06 5.185748709 -0.261088297 ATS(ph)PGPTDLETR ddPTM_HeLa_Curcumin_4h_R1 1 ATSPGPTDLETR 12 0 Q5VT06 Q5VT06 CEP350 Centrosome-associated protein 350 1 0 AT(0.122)S(0.875)PGPT(0.003)DLETR 118.87 0.0036814 8927400 3467.7 3543.5 3380.9 3451 4098.5 3679.1 2599.7 2491.4 3610.8 3384.6 TRUE FALSE FALSE 3193.227886 3849.78435 3506.199128 3436.720676 4049.628064 2916.013188 2672.640585 3251.016391 3214.704274 3502.214598 0.911773907 1.099242848 1.001137717 0.981299284 1.156304947 0.832619791 0.763128732 0.928274467 0.917906137 1 11.77405177 -5.111357886 22.52136114 0.985122221 0.833427452 0.452515891 0.081643724 7.946954022 1593.235312 0.011536282 0.029411924 7.74E-06 5.111357886 -0.151694769 ATS(ph)PLVSLYPALECR ddPTM_HeLa_Curcumin_4h_R1 2 ATSPLVSLYPALECR 15 0 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74;H7BZQ3;Q96G74-4 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 0 AT(0.064)S(0.936)PLVS(0.001)LYPALECR;AT(0.104)S(0.896)PLVSLYPALECR ; 156.2 0.00036607 669280000 2866.3 2388.09 2788.09 2261.45 2599.59 2861.3 1727.14 1015.73 3124 2401.03 TRUE FALSE FALSE 2639.42933 2594.505858 2891.419068 2252.092719 2568.591587 2267.834127 1775.5989 1325.421401 2781.305016 2484.465614 1.062373058 1.044291313 1.16379919 0.906469668 1.033860792 0.9128056 0.714680409 0.533483496 1.119478169 1 11.27871986 -4.531768585 1.189224757 1.035933527 0.41778366 0.876581752 0.064550744 0.221293476 0.354574341 0.008667692 0.148959787 2.94E-05 4.531768585 -0.618149867 ATS(ph)TATSGFAGAIGQK ddPTM_HeLa_Curcumin_4h_R1 2 ATSTATSGFAGAIGQK 16 0 E7ER27;A0A2R8YD50;P51659-3;P51659;P51659-2;E7EPL9;A0A2R8Y7L2;E7ET17 E7ER27 HSD17B4 Peroxisomal multifunctional enzyme type 2;(3R)-hydroxyacyl-CoA dehydrogenase;Enoyl-CoA hydratase 2 1 0 ATS(0.993)T(0.003)AT(0.003)S(0.001)GFAGAIGQK;ATS(0.936)T(0.064)ATSGFAGAIGQK ; 283.66 8.61E-66 31446000 6129.5 4568.9 5193 5966.5 5994.4 6747.8 4544.4 3967.2 5888 5813.7 TRUE FALSE FALSE 5644.343607 4963.815357 5385.457148 5941.812204 5922.920695 5348.230217 4671.903633 5176.781017 5242.101131 6015.725642 0.938264798 0.825139917 0.895229847 0.987713296 0.984572942 0.889041578 0.776615144 0.860541408 0.871399635 1 12.55452306 -1.000000001 0.087114719 1.076395327 0.432315495 0.000401015 0.070395203 128.7774595 0.816727473 0.84466987 9.975256352 0.1 1.000000001 -0.644079833 TDS(ph)ASADPDNLK ddPTM_HeLa_Curcumin_4h_R1 1 TDSASADPDNLK 12 0 Q96Q15;H3BR09;E9PNP6;I3L0W2 Q96Q15 SMG1 Serine/threonine-protein kinase SMG1 1 0 T(0.24)DS(0.745)AS(0.016)ADPDNLK 134.68 0.001868 14492000 1639 1073.7 1391.6 1565.5 1431.5 1989.1 3029.1 3872 1488 1416.8 TRUE FALSE FALSE 1509.271421 1166.505844 1443.17392 1559.022376 1414.430297 1576.538238 3114.088394 5052.554976 1324.770123 1466.033695 1.029492996 0.79568829 0.984407061 1.063428748 0.964800675 1.075376537 2.124158814 3.446411221 0.903642343 1 10.51770255 -4.414647408 1.864904579 0.991412794 3.823453371 0.98800488 0.085989206 0.042362631 0.190257882 0.012205247 0.186360054 3.85E-05 4.414647408 2.832040577 up RPS(ph)SPVISK ddPTM_HeLa_Curcumin_4h_R1 2 RPSSPVISK 9 1 Q96T17;Q96T17-2;Q96T17-5;Q96T17-4 Q96T17 MAP7D2 MAP7 domain-containing protein 2 1 0 RPS(0.5)S(0.5)PVISK;RPS(0.825)S(0.175)PVISK ; 91.307 0.0085426 630076000 19647.8 17010.9 16246.7 16711.4 13549.3 12028 7153.1 1957.47 19939.8 15719.2 TRUE FALSE FALSE 18092.6559 18481.2464 16848.81699 16642.25265 13387.73345 9533.257217 7353.796734 2554.293592 17752.45383 16265.44103 1.112337247 1.136227807 1.035865979 1.023166395 0.823078417 0.586105055 0.452111733 0.157038078 1.091421609 1 13.98952232 -4.911024668 0.92208384 1.064649772 0.086272867 0.973864523 0.051231591 0.12595059 0.141698551 0.009952458 0.09820559 1.23E-05 4.911024668 -0.978376905 down SPSPGGPQLS(ph)PQLPR ddPTM_HeLa_Curcumin_4h_R1 1 SPSPGGPQLSPQLPR 15 0 H7C1V4;Q9HCH0-2;Q9HCH0 H7C1V4 NCKAP5L Nck-associated protein 5-like 1 0 S(0.376)PS(0.208)PGGPQLS(0.417)PQLPR 144.08 0.00050086 44233000 1376.5 1007.9 859.88 1514.6 1293.9 1000.3 145.95 238.15 1290.4 820.75 TRUE FALSE FALSE 1267.548573 1095.018385 891.7479092 1508.332987 1278.471088 792.8265043 150.0449642 310.7608387 1148.846348 849.2710014 1.492513662 1.289362739 1.050015728 1.776032602 1.50537471 0.933537708 0.176675012 0.365914812 1.352744114 1 9.730081179 -4.910268152 3.76849048 1.284400732 0.273492107 0.781794526 0.224338417 0.090904518 2.475658999 0.037604246 0.12568443 1.23E-05 4.910268152 -1.010908625 down ATSDTLES(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 1 ATSDTLESPPK 11 0 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 0 ATSDT(0.039)LES(0.961)PPK 103.14 0.0092454 12381000 3036.3 2674.4 2728.2 2736.6 3476.1 3261.9 1861.7 1291.7 2981.6 2733.3 TRUE FALSE FALSE 2795.973651 2905.563219 2829.309492 2725.276674 3434.649778 2585.345171 1913.934291 1685.533384 2654.52594 2828.281972 0.988576698 1.027324449 1.000363302 0.963580259 1.214394396 0.914104462 0.676712687 0.595956627 0.938564813 1 11.46571024 -4.786725146 3.323506388 1.009302175 0.617129918 0.813777209 0.072311376 0.062994047 1.412704235 0.009190361 0.036183515 1.63E-05 4.786725146 -0.392172257 ATSFGSLRCQVK ddPTM_HeLa_Curcumin_4h_R1 1 ATSFGSLRCQVK 12 1 H0YBY1;P01266-2;P01266 H0YBY1 TG Thyroglobulin 0 0 107.69 0.00067171 0 294.82 201 229.1 430.4 313.87 0 136.38 180.34 218.85 177.42 FALSE FALSE TRUE 271.4846859 218.3735444 237.5906475 428.6191188 310.1273052 0 140.2064558 235.3248358 194.8427025 183.5853318 1.478792904 1.189493421 1.294170102 2.334713316 1.689281503 0 0.763712734 1.281828093 1.061319554 1 7.520306984 -5.281859715 24.99332184 1.345377382 0.690033361 0.343156143 0.466213247 787.7918111 964210.9985 0.070824504 0.158540746 5.23E-06 5.281859715 -0.655344021 ATSS(ph)SNPSSPAPDWY(ph)KDFVTDADAEVLEHSGK ddPTM_HeLa_Curcumin_4h_R1 1 ATSSSNPSSPAPDWYKDFVTDADAEVLEHSGK 32 1 P46100-5;P46100-3;P46100-4;P46100;P46100-2 P46100-5 ATRX Transcriptional regulator ATRX 2 0 AT(0.105)S(0.06)S(0.357)S(0.336)NPS(0.14)S(0.227)PAPDWY(0.598)KDFVT(0.172)DADAEVLEHS(0.005)GK 44.6 0.0077308 7213200 2333.9 1977.2 1828.5 2397.4 2118.8 2521.2 1936.9 1448.8 2480.6 2456.6 TRUE FALSE FALSE 2149.169352 2148.100358 1896.265819 2387.480194 2093.534694 1998.2747 1991.244201 1890.532451 2208.484386 2541.966667 0.845475033 0.845054495 0.745983747 0.93922561 0.823588571 0.786113652 0.783347881 0.743728262 0.868809341 1 11.3117294 -13.52287875 0.135333326 1.679676737 0.733845545 0.3194694 0.064317078 31.01165002 0.294647078 5.614372874 0.157854511 3.00E-14 13.52287875 -0.945831192 ATSS(ph)SSGSLSATGR ddPTM_HeLa_Curcumin_4h_R1 1 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 0 ATS(0.017)S(0.892)S(0.086)S(0.004)GSLSATGR 182.72 9.22E-05 5834800 2265.2 1611.7 1913.8 2062.2 2190.9 2452.7 1689.2 775.75 2617.1 1925.7 TRUE FALSE FALSE 2085.90703 1751.008166 1984.727112 2053.667163 2164.774948 1943.982372 1736.594406 1012.272604 2330.010678 1992.617932 1.046817354 0.878747571 0.996039973 1.0306377 1.086397404 0.97559213 0.871513991 0.508011389 1.169321344 1 10.9604494 -4.225332606 1.837353331 1.014052161 0.313536843 0.829015181 0.070907015 0.210122189 0.662333516 0.007561642 0.260217358 5.95E-05 4.225332606 -0.700515318 ATSS(ph)TQSLAR ddPTM_HeLa_Curcumin_4h_R1 2 ATSSTQSLAR 10 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 AT(0.007)S(0.033)S(0.913)T(0.047)QSLAR;AT(0.004)S(0.03)S(0.936)T(0.03)QSLAR ; 138.63 0.0016995 69660000 4774.4 4757.7 4411.8 4612.6 4416.7 7628.1 5002 6363.1 5646.2 4940.8 TRUE FALSE FALSE 4396.501202 5168.934388 4575.305189 4593.514283 4364.033737 6045.946074 5142.342658 8303.179898 5026.825986 5112.492432 0.859952608 1.011040008 0.894926545 0.898488231 0.853601995 1.18258289 1.005838684 1.624096272 0.983243702 1 12.31981109 -1.538358558 1.001133739 0.932469979 199.9999991 0.827651559 0.090557141 135.7815612 0.599566893 0.013440409 61457.50081 0.028949525 1.538358558 199.0675291 ATSSS(ph)SGSLSATGR ddPTM_HeLa_Curcumin_4h_R1 2 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 0 ATSS(0.052)S(0.932)S(0.006)GS(0.01)LSATGR;ATSS(0.062)S(0.868)S(0.062)GS(0.009)LSATGR ; 240.18 1.42E-28 195242000 5966.8 4009.2 4573.3 4860.2 4679.5 7122.2 5971.8 2792.4 5193.1 3663.2 TRUE FALSE FALSE 5494.521484 4355.737383 4742.790521 4840.08978 4623.700019 5644.975436 6139.352636 3643.789905 4623.429922 3790.495927 1.44955214 1.149120713 1.25123219 1.276901459 1.219814005 1.489244559 1.619670026 0.961296352 1.219742749 1 11.8881709 -9.475100972 1.142799026 0.99508684 1.32297808 0.095311793 0.187940317 0.482177766 1.099042928 0.128558376 0.029668322 3.35E-10 9.475100972 0.32789124 ATSSSNPS(ph)S(ph)PAPDWYK ddPTM_HeLa_Curcumin_4h_R1 1 ATSSSNPSSPAPDWYK 16 0 P46100-5;P46100-3;P46100-4;P46100;P46100-2 P46100-5 ATRX Transcriptional regulator ATRX 2 0 AT(0.003)S(0.022)S(0.175)S(0.279)NPS(0.566)S(0.955)PAPDWYK 104.07 0.0049557 4860000 1726.3 2282.1 2406.8 1948.8 2787.9 2450.7 1806.3 1491.1 2345.2 1805.7 TRUE FALSE FALSE 1589.661533 2479.354555 2495.998125 1940.736382 2754.656113 1942.397195 1856.979917 1945.729526 2087.937427 1868.447941 0.850792521 1.326959398 1.335867096 1.038689032 1.474301774 1.039577905 0.993862273 1.04136138 1.117471556 1 10.86762465 -7.271531595 24.88652016 0.929540911 1.178236719 0.191244685 0.165085633 537.8886606 1326383.99 0.027226067 0.031321052 5.35E-08 7.271531595 0.248695808 ATSSSNPSS(ph)PAPDWYK ddPTM_HeLa_Curcumin_4h_R1 1 ATSSSNPSSPAPDWYK 16 0 P46100-5;P46100-3;P46100-4;P46100;P46100-2 P46100-5 ATRX Transcriptional regulator ATRX 1 0 ATSSS(0.001)NPS(0.251)S(0.748)PAPDWYK 91.657 0.0088932 0 1149.4 1163.6 1226.7 1018.8 1537.7 1160.9 1230.2 704.34 1200.4 1106.3 TRUE FALSE FALSE 1058.423777 1264.176399 1272.162581 1014.584476 1519.363932 920.116254 1264.716101 919.0900236 1068.719123 1144.743843 0.924594427 1.10433125 1.111307643 0.88629826 1.327252329 0.803774801 1.104802711 0.802878329 0.933588008 1 10.16080909 -2.114614627 9.721994107 0.990664654 0.515932718 0 0.155752245 0 0 0.018108917 0 0.007680427 2.114614627 -0.474731935 ATSSSS(ph)GSLSATGR ddPTM_HeLa_Curcumin_4h_R1 1 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 0 AT(0.069)S(0.223)S(0.223)S(0.154)S(0.327)GS(0.002)LSATGR 103.11 0.0052892 0 667.37 718.74 516.58 747.06 680.01 590.85 645.22 357.47 652.77 472.49 TRUE FALSE FALSE 614.5469603 780.864683 535.7249092 743.9688637 671.9013249 468.3010497 663.3231367 466.4609574 581.1627642 488.9089923 1.256976186 1.597157539 1.095755892 1.521691921 1.374287107 0.957849123 1.356741535 0.954085453 1.188693138 1 8.93342213 -8.902462846 0.968884952 1.014632215 1.270003213 0.069389434 0.211421665 0.614037056 1.123477026 0.093801706 0.037823586 1.25E-09 8.902462846 0.255370998 ATSSSSGS(ph)LSATGR ddPTM_HeLa_Curcumin_4h_R1 3 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 0 ATSSS(0.001)S(0.026)GS(0.947)LS(0.026)ATGR;ATS(0.001)S(0.015)S(0.178)S(0.178)GS(0.612)LS(0.015)ATGR;ATSSS(0.062)S(0.177)GS(0.741)LS(0.02)ATGR ;; 209.11 2.13E-09 54123000 5655.5 4587.3 4584 4323.4 4978 5773.8 4712.9 3433.92 4887.8 4533.8 TRUE FALSE FALSE 5207.861207 4983.805771 4753.887072 4305.510916 4918.640601 4576.248796 4845.13129 4480.9064 4351.620569 4691.349213 1.110098816 1.062339541 1.013330464 0.917755367 1.048449045 0.975465391 1.032779925 0.955142369 0.927584021 1 12.19578718 -6.605352135 5.046703719 1.054005612 0.989117208 0.000360647 0.058337985 0.216510812 9.699367022 0.008160233 0.011639551 2.48E-07 6.605352135 -0.064888404 ATSSSSGSLS(ph)ATGR ddPTM_HeLa_Curcumin_4h_R1 1 ATSSSSGSLSATGR 14 0 Q03252 Q03252 LMNB2 Lamin-B2 1 0 ATS(0.001)S(0.017)S(0.009)S(0.009)GS(0.009)LS(0.951)AT(0.002)GR 90.689 0.0093808 4709200 1004.6 824.84 753.27 878.89 920.31 1148 881.67 676.88 1211.9 854.01 TRUE FALSE FALSE 925.08485 896.1354942 781.1868488 875.2533861 909.3359043 909.8918594 906.4072873 883.257596 1078.957602 883.6867839 1.04684699 1.014087243 0.88400875 0.990456576 1.029025126 1.029654258 1.025711037 0.999514321 1.220972885 1 9.787391298 -6.984724656 24.99993968 1.022561411 0.9936689 0.085854751 0.074904915 482.7510177 790076.7361 0.007248374 0.009524224 1.04E-07 6.984724656 -0.028892511 ATSVALPGWS(ph)PSETR ddPTM_HeLa_Curcumin_4h_R1 2 ATSVALPGWSPSETR 15 0 Q16513-3;Q16513-2;Q16513;Q16513-4;B1AL79;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 0 ATSVALPGWS(0.912)PS(0.088)ETR;ATS(0.001)VALPGWS(0.978)PS(0.02)ET(0.001)R ; 230.67 6.44E-21 100454000 9091.3 7869.3 7938.7 8891.1 9261.2 12380.1 11075.5 3957 9467.1 6918.5 TRUE FALSE FALSE 8371.714012 8549.487227 8232.915206 8854.310984 9150.766239 9812.327708 11386.24872 5163.471084 8428.582816 7158.91736 1.169410623 1.194243039 1.150022383 1.236822628 1.278233255 1.370644081 1.590498695 0.721264239 1.177354395 1 12.80552571 -8.272344597 0.432094179 0.985664673 1.264340807 0.026782946 0.211816382 1.464801664 0.617004502 0.173386888 0.077372337 5.34E-09 8.272344597 0.278676135 QNS(ph)IENDIEEK ddPTM_HeLa_Curcumin_4h_R1 2 QNSIENDIEEK 11 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;F5GXF5;Q12830-2 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 0 QNS(1)IENDIEEK;QNS(1)IENDIEEK ; 185.27 8.83E-05 9738200 2314.5 1600.94 1786.82 2571 2638.3 5169.2 7140.8 8532.1 2577.5 2024.03 TRUE FALSE FALSE 2131.304883 1739.31812 1853.041121 2560.361883 2606.839996 4097.049651 7341.15163 11133.49801 2294.754699 2094.364892 1.017637801 0.830475208 0.884774725 1.222500383 1.244692367 1.95622533 3.50519227 5.315930408 1.095680465 1 11.0322971 -4.414064466 1.117161277 0.988450717 6.787916737 0.995547761 0.093083221 0.053754038 0.064273487 0.013644973 0.341330706 3.85E-05 4.414064466 5.799466019 up ATT(ph)PADGEEPAPEAEALAAAR ddPTM_HeLa_Curcumin_4h_R1 4 ATTPADGEEPAPEAEALAAAR 21 0 Q5JZ02;Q96S44 Q5JZ02 TP53RK TP53-regulating kinase 1 0 AT(0.06)T(0.94)PADGEEPAPEAEALAAAR;ATT(1)PADGEEPAPEAEALAAAR;AT(0.093)T(0.907)PADGEEPAPEAEALAAAR;ATT(1)PADGEEPAPEAEALAAAR ;;; 330.13 2.82E-138 93381000 7277.3 5791.9 6723 6899.3 5806.3 7095.7 5201.5 3218.67 7409.3 6580.2 TRUE FALSE FALSE 6701.294026 6292.526028 6972.160294 6870.752525 5737.063665 5623.971835 5347.440091 4200.027666 6596.518327 6808.86146 0.984201847 0.924167141 1.02398328 1.009089782 0.84258781 0.825978303 0.785364796 0.616847279 0.968813709 1 12.73319786 -4.07621558 0.575882358 0.994600692 0.306468214 0.888927423 0.041053519 0.903311154 0.17509551 0.007471955 0.43316873 8.39E-05 4.07621558 -0.688132478 ATT(ph)PPNQGRPDS(ph)PVYANLQELK ddPTM_HeLa_Curcumin_4h_R1 1 ATTPPNQGRPDSPVYANLQELK 22 1 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 2 0 AT(0.116)T(0.884)PPNQGRPDS(0.975)PVY(0.025)ANLQELK 79.332 0.0013985 23496000 2861.9 1742.5 2003.5 2169.5 2213.8 1885.7 1463.6 1758.6 2384.3 2066.5 TRUE FALSE FALSE 2635.377595 1893.113936 2077.751472 2160.523184 2187.401881 1494.584564 1504.664677 2294.789044 2122.748255 2138.310721 1.232457738 0.885331546 0.971678929 1.010387855 1.022957917 0.698955745 0.7036698 1.073178478 0.992722075 1 11.06225579 -6.085862659 0.873874649 1.098350981 0.831878268 0.16587067 0.140236322 0.520890789 0.775449577 0.027737538 0.071865764 8.21E-07 6.085862659 -0.266472713 ATT(ph)PQLTDVSEDLDQQSLPSEPEETLSR ddPTM_HeLa_Curcumin_4h_R1 1 ATTPQLTDVSEDLDQQSLPSEPEETLSR 28 0 Q8NC44;H7C3D5;C9JIF3 Q8NC44 FAM134A Protein FAM134A 1 0 AT(0.207)T(0.792)PQLT(0.001)DVSEDLDQQSLPSEPEETLSR 132.62 5.27E-10 3591800 250.38 332.06 354.52 412.43 315.79 284.53 288.22 172.34 411.63 359.07 TRUE FALSE FALSE 230.5621588 360.7617868 367.6588231 410.7234739 312.0244105 225.5152707 296.3066775 224.8856726 366.4752188 371.5476558 0.62054532 0.970970429 0.989533421 1.105439551 0.839796472 0.606961899 0.797493061 0.605267371 0.986347816 1 8.537403457 -5.357730216 6.603025602 0.865074233 0.683396234 0.357149259 0.142271438 0.330148421 19.17252212 0.026029271 0.058659306 4.39E-06 5.357730216 -0.181678 ATT(ph)PSLPSVDNEFK ddPTM_HeLa_Curcumin_4h_R1 2 ATTPSLPSVDNEFK 14 0 A0A087WU78;A0A087WWC4;Q6T4R5-4;Q6T4R5-3;Q6T4R5-2;Q6T4R5 A0A087WU78 NHS Nance-Horan syndrome protein 1 0 AT(0.086)T(0.901)PS(0.011)LPS(0.001)VDNEFK;ATT(0.991)PS(0.009)LPSVDNEFK ; 182.37 0.00028234 13779800 7798.9 5900.4 6186.4 6665.4 5478.6 5195.2 2754.19 2561.65 7767.8 6407.3 TRUE FALSE FALSE 7181.608836 6410.404284 6415.673426 6637.820341 5413.271273 4117.656958 2831.465159 3342.685293 6915.691774 6629.953198 1.083206566 0.9668853 0.967680048 1.001186606 0.816487102 0.621068782 0.427071666 0.50417932 1.043098129 1 12.69478297 -5.327212249 1.359286879 1.030630374 0.446520687 0.965075592 0.042453417 0.060515839 0.20693424 0.007332131 0.027801013 4.71E-06 5.327212249 -0.584109687 ATTKPPPAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 ATTKPPPAKK 10 2 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 1 ATTKPPPAK(1)K 102.53 0.00049143 0 6039.1 6086.6 6297.7 5283.7 5633.8 7586.7 5949.2 5757.9 5292 5506.8 FALSE TRUE FALSE 5561.098863 6612.698583 6531.098302 5261.837449 5566.620615 6013.1329 6116.118541 7513.457204 4711.48084 5698.16089 0.975946269 1.160496994 1.146176534 0.923427322 0.97691531 1.055276082 1.07334957 1.318575826 0.826842367 1 12.47628064 -4.024536726 1.542807367 1.008901937 1.60461888 0.503135578 0.092747043 1.094706538 1.516173032 0.011162626 1.170832657 9.45E-05 4.024536726 0.595716942 ATVTPS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 4 ATVTPSPVK 9 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 ATVT(0.1)PS(0.9)PVK;AT(0.002)VT(0.161)PS(0.837)PVK;AT(0.001)VT(0.411)PS(0.588)PVK;AT(0.141)VT(0.141)PS(0.718)PVK ;;; 131.12 0.0037434 1856080000 54732 39182.9 52970 45619.3 67038 60324 59934 45675.6 38835.5 37855.7 TRUE FALSE FALSE 50399.90445 42569.69528 54933.1148 45430.53942 66238.61563 47812.12241 61615.58674 59601.88018 34575.34281 39171.18276 1.286657714 1.086760529 1.402385911 1.159794937 1.691003717 1.2205943 1.572982545 1.521574688 0.882672934 1 15.25750507 -1.00000012 0.044888312 0.11632085 3.440527481 0.598478198 0.15773779 275.5235892 0.947764146 18.08995708 66.63432414 0.099999972 1.00000012 3.324206631 ATVTPS(ph)PVKGK ddPTM_HeLa_Curcumin_4h_R1 1 ATVTPSPVKGK 11 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 AT(0.015)VT(0.38)PS(0.605)PVKGK 75.102 0.014746 8184000 2710.7 2106.5 2111.3 2062.3 2104.3 2877.9 2755.4 1631.2 2455.7 2071.8 TRUE FALSE FALSE 2496.145235 2288.576474 2189.546635 2053.766749 2079.207597 2280.991099 2832.709108 2128.545371 2186.315854 2143.794896 1.164358232 1.067535182 1.021341472 0.958005243 0.969872445 1.063996889 1.321352669 0.992886668 1.019834434 1 11.06595117 -9.74566529 1.691151572 1.000013803 1.086227699 0.032672873 0.102665963 0.830198812 4.296624461 0.077970437 0.016874877 1.80E-10 9.74566529 0.086213896 KKDDSFLGK(ac)LGGTLAR ddPTM_HeLa_Curcumin_4h_R1 1 KKDDSFLGKLGGTLAR 16 3 Q9NVD7-2;Q9NVD7 Q9NVD7-2 PARVA Alpha-parvin 0 1 KKDDSFLGK(1)LGGTLAR 58.688 0.018928 898930 1406.2 1121 1170 1342 1181.1 1168 1313.7 2153.8 1551 1060 FALSE TRUE FALSE 1294.897786 1217.894245 1213.361229 1336.44716 1167.016154 925.7436339 1350.558886 2810.483705 1380.85918 1096.834921 1.180576732 1.110371508 1.106238693 1.218457886 1.063985228 0.84401364 1.231323748 2.562357973 1.258948957 1 10.09913069 -4.267180115 4.184837061 1.083857531 2.673856804 0.938198128 0.112008909 0.032889745 1.284062949 0.014694875 0.154947952 5.41E-05 4.267180115 1.589999273 up ATVVESSEK ddPTM_HeLa_Curcumin_4h_R1 2 ATVVESSEK 9 0 P61981 P61981 YWHAG "14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed" 0 0 ; ; 186.16 8.39E-17 7759800 6777.4 7153.6 6809.2 4885.3 5052.7 8065.4 5383.1 5926.5 5128.7 6233.2 FALSE FALSE TRUE 6240.961639 7771.925308 7061.554942 4865.085923 4992.449853 6392.545124 5534.135298 7733.462568 4566.094441 6449.803236 0.96762047 1.20498642 1.094848119 0.754299898 0.774046846 0.991122503 0.858031648 1.199023022 0.707943215 1 12.65503943 -6.290917736 24.913927 1.011855869 0.908487296 0.049455497 0.16561423 1121.200924 947591.8564 0.020855856 0.03186074 5.12E-07 6.290917736 -0.103368573 AVAAPRPDR ddPTM_HeLa_Curcumin_4h_R1 1 AVAAPRPDR 9 1 O75534-2;O75534;O75534-3;O75534-4;E9PLT0 O75534-2 CSDE1 Cold shock domain-containing protein E1 0 0 90.601 0.0080274 0 802.45 555.15 601.04 500.2 561.08 685.57 460.84 781.54 878.05 796.92 FALSE FALSE TRUE 738.9352358 603.1346923 623.3150711 498.1303049 554.3894875 543.375054 473.7699301 1019.827948 781.7301118 824.6129107 0.896099523 0.731415534 0.755888082 0.604077742 0.672302701 0.658945606 0.574536154 1.236735364 0.94799645 1 9.687573239 -7.471099743 1.450531328 0.966193194 0.72548295 0.208364303 0.1764601 0.355431405 1.474601207 0.03378677 0.036778807 3.38E-08 7.471099743 -0.240710243 AVAGVMITAS(ph)HNR ddPTM_HeLa_Curcumin_4h_R1 1 AVAGVMITASHNR 13 0 Q6PCE3 Q6PCE3 PGM2L1 "Glucose 1,6-bisphosphate synthase" 1 0 AVAGVMIT(0.085)AS(0.915)HNR 81.327 0.012621 22495000 4935.5 4083.7 4209.4 4699.2 4592.9 6549.7 4546.5 4179.6 5095.5 5203.9 TRUE FALSE FALSE 4544.849967 4436.676831 4365.404067 4679.755956 4538.132667 5191.21839 4674.062554 5453.940799 4536.536398 5384.735138 0.844024794 0.823935944 0.810699868 0.869078206 0.842777324 0.964061975 0.868020884 1.012852194 0.84248088 1 12.39465967 -3.335777092 23.76128523 0.905395308 0.891852315 0 0.073418675 0 0 0.011109578 0 0.000461554 3.335777092 -0.013542993 AVAQALEVIPR ddPTM_HeLa_Curcumin_4h_R1 1 AVAQALEVIPR 11 0 P49368;B4DUR8;P49368-2 P49368 CCT3 T-complex protein 1 subunit gamma 0 0 112.36 0.0038237 1501300 456.53 306.08 352.65 299.54 302.95 584.53 530.72 509.44 507.33 396.96 FALSE FALSE TRUE 420.3951688 332.5361913 365.7195192 298.3005828 299.3375191 463.291889 545.6105748 664.7659108 451.6771683 410.7543305 1.023471057 0.809574402 0.890360715 0.726226264 0.728750732 1.127905063 1.328313628 1.618402684 1.0996285 1 8.682131975 -4.640998073 2.05334624 0.948832493 1.606933739 0.76338985 0.128827035 0.158724032 1.157938315 0.020231266 0.145716887 2.29E-05 4.640998073 0.658101246 AVAS(ph)PEATVSQTDENK ddPTM_HeLa_Curcumin_4h_R1 3 AVASPEATVSQTDENK 16 0 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1-5;Q641Q2;F8W7U3;E7ESD2;Q641Q2-2;A0A087WYF6 A0A0A0MR88;Q641Q2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 0 AVAS(1)PEATVSQTDENK;AVAS(0.996)PEAT(0.004)VSQTDENK;AVAS(1)PEATVSQTDENK ;; 293.77 8.92E-80 178907100 7548.64 6497.2 6814.09 7047.5 7622.2 8076.74 6831.54 4929.7 6640.18 5242.39 TRUE FALSE FALSE 6951.157179 7058.789017 7066.62617 7018.339312 7531.310243 6401.53308 7023.214626 6432.742836 5911.768867 5424.562662 1.281422598 1.301264168 1.30270892 1.2938074 1.388371877 1.180101232 1.294706147 1.185854646 1.089814836 1 12.40529111 -9.090793128 0.733849595 0.987597081 1.283174393 0.681110367 0.06270681 0.265608258 0.244994034 0.046209313 0.011785745 8.11E-10 9.090793128 0.295577311 AVAS(ph)PEATVSQTDENKAR ddPTM_HeLa_Curcumin_4h_R1 3 AVASPEATVSQTDENKAR 18 1 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1-5;Q641Q2;F8W7U3;E7ESD2;Q641Q2-2;A0A087WYF6 A0A0A0MR88;Q641Q2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 0 AVAS(1)PEATVSQTDENKAR;AVAS(0.693)PEAT(0.307)VSQTDENKAR;AVAS(0.996)PEAT(0.004)VSQTDENKAR ;; 152.94 6.97E-05 124227900 4546.2 3698.6 3502.6 3860.7 2993.04 4953.3 3140.42 2823.97 5100.1 3763.86 TRUE FALSE FALSE 4186.363473 4018.290503 3632.409437 3844.725446 2957.349953 3925.929745 3228.531733 3684.985453 4540.63179 3894.653855 1.074900011 1.031745221 0.932665539 0.987180271 0.759335762 1.008030467 0.828965 0.946165074 1.165862734 1 11.9272794 -6.497216211 1.716585326 1.036294522 0.895342955 0.46070562 0.0810905 0.230271795 1.352502451 0.01099095 0.017839859 3.18E-07 6.497216211 -0.140951567 AVCGSYS(ph)FTWSAAR ddPTM_HeLa_Curcumin_4h_R1 1 AVCGSYSFTWSAAR 14 0 A6ND36 A6ND36 FAM83G Protein FAM83G 1 0 AVCGS(0.029)YS(0.935)FT(0.018)WS(0.018)AAR 96.745 0.0067304 11401000 967.21 1319.8 904.9 1693.7 1008.2 1115.2 743.39 563.46 1600.3 1131.2 TRUE FALSE FALSE 890.6543079 1433.877631 938.43639 1686.691918 996.1778735 883.8949491 764.2475227 735.2563601 1424.751094 1170.509116 0.760911894 1.225003387 0.801733517 1.440989989 0.851063747 0.755137177 0.652918899 0.628150905 1.21720632 1 10.19292045 -5.173559178 2.842794791 0.945401413 0.652758423 0.324614374 0.215114565 0.283594336 4.42854337 0.029546923 0.086429893 6.71E-06 5.173559178 -0.292642989 AVDDGVNTFK ddPTM_HeLa_Curcumin_4h_R1 2 AVDDGVNTFK 10 0 P50990-2;P50990;P50990-3 P50990-2 CCT8 T-complex protein 1 subunit theta 0 0 ; ; 202.2 2.71E-26 14075200 11831.1 8975.7 10328.8 10849.3 10809 12123.7 9355.7 9024 11522.5 10277.9 FALSE FALSE TRUE 10894.65595 9751.519513 10711.59441 10804.40847 10680.10973 9609.107958 9618.195762 11775.37606 10258.51058 10635.05626 1.024409809 0.916922231 1.007196779 1.01592396 1.004236317 0.903531465 0.904385979 1.107222733 0.964593917 1 13.37654004 AVDDGVNTFK(ac)VLTR ddPTM_HeLa_Curcumin_4h_R1 1 AVDDGVNTFKVLTR 14 1 P50990-2;P50990;P50990-3 P50990-2 CCT8 T-complex protein 1 subunit theta 0 1 AVDDGVNTFK(1)VLTR 153.75 0.00090036 1352300 452.73 365.89 551.69 618.74 485.43 641.14 325.91 449.94 652.67 348.48 FALSE TRUE FALSE 416.8959428 397.5159012 572.1361167 616.1798178 479.6415643 508.1603369 335.0541575 587.1246347 581.0737339 360.5896541 1.156150594 1.102405176 1.586668143 1.708811695 1.330158974 1.409248244 0.929184056 1.628234832 1.611454259 1 8.494214194 -6.837543731 8.164988754 1.077122919 1.415758231 0.041326858 0.26504279 0.203573422 19.34946334 0.033569934 0.044206624 1.45E-07 6.837543731 0.338635311 AVDIPHMDIEALK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 AVDIPHMDIEALKK 14 1 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 1 AVDIPHMDIEALK(1)K 115.34 6.21E-05 1942300 1258.8 1351.7 976.97 1203 1739.7 2578.5 1866.8 2017.2 2552.4 1150.8 FALSE TRUE FALSE 1159.164652 1468.534925 1013.177368 1198.022305 1718.955214 2043.690034 1919.177384 2632.234994 2272.408106 1190.790214 0.973441533 1.233244032 0.850844553 1.006073354 1.443541602 1.716246917 1.611683872 2.210494311 1.908319432 1 10.21770356 -4.951637181 0.785574866 0.985779808 2.245988955 0.431024113 0.327780389 0.288722412 0.221028654 0.024159215 0.258379383 1.12E-05 4.951637181 1.260209147 AVDS(ph)LVPIGR ddPTM_HeLa_Curcumin_4h_R1 1 AVDSLVPIGR 10 0 P25705;P25705-2;P25705-3;K7ERX7;K7EK77;K7ENJ4 P25705 ATP5A1 "ATP synthase subunit alpha, mitochondrial" 1 0 AVDS(1)LVPIGR 101.39 0.011652 2432000 1706.1 1735.5 1425.2 1712.9 2009.4 2801.1 1752.1 1035.2 2287.7 1598.6 TRUE FALSE FALSE 1571.060385 1885.508887 1478.019166 1705.812474 1985.439217 2220.120285 1801.25921 1350.827715 2036.745034 1654.151231 0.949768289 1.139864875 0.893521184 1.031231269 1.200276722 1.342150732 1.088932606 0.816628909 1.231293122 1 10.69187542 -5.95967553 7.84964934 0.983929413 1.12594634 0 0.156342642 0.292874025 48.67211071 0.019816259 0.035926146 1.10E-06 5.95967553 0.142016927 AVDS(ph)SSEEIEVEVPVVDRR ddPTM_HeLa_Curcumin_4h_R1 2 AVDSSSEEIEVEVPVVDRR 19 1 D6RB01;Q9Y6X4 D6RB01 FAM169A Soluble lamin-associated protein of 75 kDa 1 0 AVDS(0.987)S(0.006)S(0.006)EEIEVEVPVVDRR;AVDS(0.939)S(0.03)S(0.03)EEIEVEVPVVDRR ; 198.35 7.57E-11 34237000 2553.7 2087.16 2049.2 2659.3 2445.1 2800.9 2339.6 2023.15 2587.1 2221.18 TRUE FALSE FALSE 2351.57195 2267.56481 2125.145155 2648.296521 2415.943779 2219.961767 2405.242879 2639.999122 2303.301603 2298.36584 1.023149539 0.986598726 0.92463311 1.15225195 1.051157191 0.965887035 1.046501317 1.14864182 1.00214751 1 11.16639274 -6.266881355 24.99942997 1.003113319 1.064270193 0.343696959 0.05645374 536.5937299 2465014.818 0.008682717 0.013518726 5.41E-07 6.266881355 0.061156874 AVDSLVPIGR ddPTM_HeLa_Curcumin_4h_R1 2 AVDSLVPIGR 10 0 P25705;P25705-2;P25705-3;K7ERX7;K7EK77;K7ENJ4 P25705 ATP5A1 "ATP synthase subunit alpha, mitochondrial" 0 0 ; ; 119.21 0.0030619 11281400 8561.8 9164.4 7496.5 11167.9 8654.3 13106.2 8920.5 7268.1 11792.8 8163.5 FALSE FALSE TRUE 7884.124496 9956.5299 7774.326885 11121.69019 8551.103125 10387.82638 9170.785222 9484.110232 10499.15934 8447.181017 0.933343855 1.178680779 0.920345719 1.316615586 1.012302578 1.229738816 1.085662211 1.122754468 1.242918711 1 13.04425425 -6.936835844 1.339883624 0.969873022 1.135849429 0 0.138334498 0.333546821 1.183158312 0.018224026 0.024949755 1.16E-07 6.936835844 0.165976407 AVDSQILPK ddPTM_HeLa_Curcumin_4h_R1 2 AVDSQILPK 9 0 Q02878 Q02878 RPL6 60S ribosomal protein L6 0 0 ; ; 145.17 1.02E-05 20033500 18618 14797.4 16946.7 16487.9 16359.2 20342 15167 15993.7 17437.6 14911.7 FALSE FALSE TRUE 17144.36565 16076.42132 17574.75961 16419.67744 16164.12722 16122.8399 15592.5452 20870.1055 15524.73891 15429.88047 1.111114613 1.041901871 1.13900815 1.064148065 1.04758603 1.044910227 1.01054219 1.352577264 1.006147711 1 13.91343926 -1.0004767 0.012350759 1.83E-06 2.359237648 0.224357709 0.087796907 10173.34803 9.81043631 781.2386233 1121.960178 0.099890296 1.0004767 2.359235822 AVEES(ph)SDEER ddPTM_HeLa_Curcumin_4h_R1 2 AVEESSDEER 10 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 0 AVEES(0.614)S(0.386)DEER;AVEES(0.635)S(0.365)DEER ; 126.03 0.003523 5065500 3369 2770.6 3472.7 3046.4 3265.4 3269.6 2467 2264.4 2698.4 3029.2 TRUE FALSE FALSE 3102.340095 3010.078318 3601.401317 3033.794804 3226.462238 2591.448104 2536.21738 2954.805136 2402.392271 3134.464475 0.989751238 0.960316616 1.148968618 0.967882976 1.029350393 0.826759443 0.809138978 0.942682605 0.766444249 1 11.61400326 -5.26201078 24.99968707 1.004081661 0.8544882 0.22444601 0.095996728 26.3294107 1151993.767 0.00797447 0.018921499 5.47E-06 5.26201078 -0.149593461 AVEESS(ph)DEERQR ddPTM_HeLa_Curcumin_4h_R1 1 AVEESSDEERQR 12 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 0 AVEES(0.19)S(0.81)DEERQR 78.287 0.011515 9229900 3156.4 2445.4 2485 2270.5 2303.1 2360 2025.2 1906 2953 2494.9 TRUE FALSE FALSE 2906.567609 2656.76948 2577.096286 2261.105273 2275.637037 1870.509397 2082.021661 2487.130626 2629.063288 2581.597589 1.125879425 1.029118361 0.998256388 0.875855045 0.881484026 0.724554983 0.806485747 0.963407557 1.018386173 1 11.33404842 -6.295161577 1.728453981 1.059367014 0.832082236 0.674995312 0.064474783 0.157355633 0.918172418 0.011675228 0.020652803 5.07E-07 6.295161577 -0.227284778 DGHAT(ph)DEEKLASTSCGQK ddPTM_HeLa_Curcumin_4h_R1 1 DGHATDEEKLASTSCGQK 18 1 A0A0C4DGD3;E5RFM9;E7ET87;E7EVI4;R4GMT7;A0A0C4DGD5;H0YAY0;H0YBT8;O75410-6;O75410-4;O75410-5;O75410-10;O75410-3;O75410-7;O75410-9;O75410;O75410-2 A0A0C4DGD3 TACC1 Transforming acidic coiled-coil-containing protein 1 1 0 DGHAT(1)DEEKLASTSCGQK 58.461 0.01082 14696000 4965.7 4499.7 4505.3 4655.5 4344.9 4270.5 2440.8 1471.7 5242.2 4373.7 TRUE FALSE FALSE 4572.659605 4888.634018 4672.270381 4636.236775 4293.089905 3384.750162 2509.282279 1920.414555 4667.143775 4525.685749 1.01037939 1.080197408 1.032389485 1.024427464 0.948605392 0.747897744 0.554453495 0.4243367 1.031256705 1 12.1439207 -4.907714658 1.397650153 1.015909237 0.409939522 0.986726031 0.025081321 0.045643174 0.149142254 0.004314102 0.027686657 1.24E-05 4.907714658 -0.605969714 down AVEHINK(ac)TIAPALVSK ddPTM_HeLa_Curcumin_4h_R1 2 AVEHINKTIAPALVSK 16 1 P06733;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8Y6I8 P06733 ENO1 Alpha-enolase;Enolase 0 1 ; AVEHINK(1)TIAPALVSK;AVEHINK(1)TIAPALVSK 126.91 0.0011542 12876300 11901 9807.3 11163.1 10498 10729.7 16448.2 12927.4 14872.9 13109.7 12122.8 FALSE TRUE FALSE 10959.02329 10654.99931 11576.81431 10454.56206 10601.75534 13036.65791 13290.10805 19407.57874 11671.59871 12544.0664 0.873642003 0.849405526 0.922891664 0.833426875 0.845160971 1.039268886 1.059473669 1.547152106 0.930447778 1 13.61471748 -3.944199585 1.372881771 0.919033777 2.299352451 0.91079831 0.060077413 0.674580761 0.629110308 0.010664563 1.587204557 0.00011371 3.944199585 1.380318674 AVEHMFETEDGSKDEWR ddPTM_HeLa_Curcumin_4h_R1 1 AVEHMFETEDGSKDEWR 17 1 Q9Y657 Q9Y657 SPIN1 Spindlin-1 0 0 43.05 0.019964 10238000 2820.6 2103.4 2696.2 2333.9 2632.5 3079.8 2490.1 2368.9 2874.5 2746.5 FALSE FALSE TRUE 2597.346534 2285.208523 2796.123544 2324.24294 2601.109157 2441.014764 2559.965504 3091.166705 2559.174542 2841.940671 0.913934116 0.804101418 0.983878225 0.817836545 0.915258078 0.858925307 0.90078077 1.08769572 0.900502452 1 11.47266072 -8.844314106 0.916305545 0.995288143 0.90572252 0 0.082738046 0.687447868 1.128684677 0.035562721 0.014516614 1.43E-09 8.844314106 -0.089565624 AVELAANTK ddPTM_HeLa_Curcumin_4h_R1 2 AVELAANTK 9 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 0 ; ; 140.75 1.61E-05 19108200 12464.4 8084.7 10921.3 9963.2 10089.8 13925.1 10529.3 10476.8 10414.7 8930.4 FALSE FALSE TRUE 11477.82959 8783.505443 11326.05299 9921.974918 9969.485725 11036.87729 10824.72382 13671.12809 9272.233466 9240.730735 1.24209112 0.950520656 1.22566638 1.073721895 1.078863351 1.194372784 1.171414267 1.479442317 1.003409117 1 13.17379123 -1 0.020151125 1.20E-07 2.672418252 0.34353168 0.119951304 3104.776565 4.870947841 239.9562489 432.8667684 0.1 1 2.672418132 AVFPS(ph)IVGR ddPTM_HeLa_Curcumin_4h_R1 1 AVFPSIVGR 9 0 P60709;A0A2R8Y793;P63267-2;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;Q6S8J3;C9JZR7;A5A3E0;C9JTX5;P0CG38;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG2;POTEE;POTEF;POTEI;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 1 0 AVFPS(1)IVGR 92.239 0.01768 9960500 1216.5 1350.7 1128.8 1438.4 1587.6 1486.1 1381.9 1346.8 1152 1195.3 TRUE FALSE FALSE 1120.212741 1467.448489 1170.634321 1432.448282 1568.668907 1177.866108 1420.672395 1757.43312 1025.628482 1236.836586 0.90570796 1.186453009 0.946474526 1.158154843 1.268291159 0.952321529 1.14863387 1.420909714 0.829235239 1 10.27243919 -1 0.301633972 0.958472182 4.24886017 0.480694268 0.12638549 31.80797572 0.406907579 0.045389235 57.36670953 0.1 1 3.290387988 AVFPS(ph)IVGRPR ddPTM_HeLa_Curcumin_4h_R1 2 AVFPSIVGRPR 11 1 P60709;A0A2R8Y793;P63267-2;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;Q6S8J3;C9JZR7;A5A3E0;C9JTX5;P0CG38;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG2;POTEE;POTEF;POTEI;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 1 0 AVFPS(1)IVGRPR;AVFPS(1)IVGRPR ; 118.76 0.0019064 347910000 8890 6763.6 7698.4 8495 8151.9 9359.8 7529.9 6646.4 9109.2 7376.5 TRUE FALSE FALSE 8186.347119 7348.215446 7983.709476 8459.849941 8054.693917 7418.471973 7741.168728 8672.856764 8109.94355 7632.832826 1.072517544 0.962711435 1.045969388 1.108349958 1.055269269 0.971915951 1.014193407 1.136256612 1.062507687 1 12.89800288 -9.587453968 1.339933992 0.999701881 1.046119148 0 0.054689142 0.880077908 2.804176145 0.03729742 0.008436606 2.59E-10 9.587453968 0.046417266 AVFPSIVGR ddPTM_HeLa_Curcumin_4h_R1 2 AVFPSIVGR 9 0 P60709;A0A2R8Y793;P63267-2;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;Q6S8J3;C9JZR7;A5A3E0;C9JTX5;P0CG38;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG2;POTEE;POTEF;POTEI;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 0 0 ; ; 139.88 5.18E-05 47933000 3194.8 2468.5 3236.9 2814.5 3230.5 3523.4 3046.6 2765.6 3021.4 2524.4 FALSE FALSE TRUE 2941.928209 2681.866141 3356.862361 2802.854345 3191.978397 2792.607123 3132.079396 3608.818709 2689.959979 2612.122712 1.126259572 1.026699905 1.285108983 1.073017868 1.221986388 1.06909492 1.199055229 1.381565534 1.029798473 1 11.35100696 -1 0.099287514 0.915389919 1.924144078 0.471476192 0.087205697 82.36755537 0.583868507 0.699292388 11.37048733 0.1 1 1.008754159 AVFPSIVGRPR ddPTM_HeLa_Curcumin_4h_R1 5 AVFPSIVGRPR 11 1 P60709;A0A2R8Y793;P63267-2;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;Q6S8J3;C9JZR7;A5A3E0;C9JTX5;P0CG38;F8WCH0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG2;POTEE;POTEF;POTEI;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 0 0 ;;;; ;;;; 206.73 9.80E-23 421136360 18918.7 11242.47 15640.91 12771.92 16011.78 20594.24 16964.06 17930.15 15657.17 14752.3 FALSE FALSE TRUE 17421.26493 12214.21901 16220.57588 12719.07318 15820.84998 16322.76248 17440.02587 23396.97019 13939.61762 15264.94133 1.141259869 0.800148441 1.062603225 0.833221229 1.036417346 1.069297427 1.14248889 1.532725852 0.913178592 1 13.89793442 -4.141844997 1.773323068 1.028813242 1.817647474 0.686267845 0.109354087 0.60010163 1.457914374 0.015869082 0.871334397 7.21E-05 4.141844997 0.788834233 AVFVDLEPTVIDEVR ddPTM_HeLa_Curcumin_4h_R1 8 AVFVDLEPTVIDEVR 15 0 Q9BQE3;F5H5D3;A0A1W2PQM2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;P68363;P68363-2 Q9BQE3;P68363 TUBA1C;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-1B chain 0 0 ;;;;;;; ;;;;;;; 277.15 1.54E-62 144781160 15374.17 12527.36 13965.02 14769.22 13522.99 15853.21 11689.47 11148.61 14667.19 12630.574 FALSE FALSE TRUE 14157.28822 13610.16918 14482.57593 14708.10888 13361.73718 12565.07554 12017.44507 14547.76987 13058.23595 13069.48551 1.083232252 1.041369928 1.10812135 1.125377803 1.022361375 0.961405523 0.919504066 1.113109606 0.99913925 1 13.67391473 -5.521824943 24.99883724 1.052400365 0.990444039 0.169431007 0.060006593 52.27411754 1240070.417 0.008916101 0.018017115 3.01E-06 5.521824943 -0.061956326 AVFVDLEPTVIDEVRT(ph)GTYR ddPTM_HeLa_Curcumin_4h_R1 2 AVFVDLEPTVIDEVRTGTYR 20 1 Q9BQE3;F5H5D3;A0A1W2PQM2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;P68363;P68363-2 Q9BQE3;P68363 TUBA1C;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-1B chain 1 0 AVFVDLEPT(0.325)VIDEVRT(0.471)GT(0.155)Y(0.05)R;AVFVDLEPT(0.042)VIDEVRT(0.565)GT(0.215)Y(0.179)R ; 64.749 0.0083111 5921500 2518.51 1889.16 2115.88 2406.74 2313.86 3250.7 2310.53 1858.11 3063.8 2159.01 TRUE FALSE FALSE 2319.167276 2052.450572 2194.296374 2396.781548 2286.268731 2576.468177 2375.357253 2424.639185 2727.708805 2234.035437 1.038106754 0.918718897 0.982211982 1.072848491 1.023380692 1.153279905 1.063258538 1.08531814 1.220978307 1 11.12543636 -5.750957701 1.786021845 1.008193235 1.093485839 0.039156936 0.080047884 0.26100355 1.689390088 0.006841364 0.015813822 1.77E-06 5.750957701 0.085292604 AVGAQASVGSRS(ph)EGEGEAASADDGSLNTSGAGPK ddPTM_HeLa_Curcumin_4h_R1 1 AVGAQASVGSRSEGEGEAASADDGSLNTSGAGPK 34 1 M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8;M0R2I2 M0QXG9 BABAM1 BRISC and BRCA1-A complex member 1 1 0 AVGAQASVGS(0.012)RS(0.605)EGEGEAAS(0.284)ADDGS(0.097)LNT(0.001)SGAGPK 115.63 2.34E-18 13364000 1304.3 950.47 1142.5 1173.2 1046.6 1172.5 966.84 921.32 1469.2 1132.4 TRUE FALSE FALSE 1201.063279 1032.624392 1184.842055 1168.345609 1034.119979 929.3102832 993.9669283 1202.226227 1308.032436 1171.750816 1.025015953 0.881266202 1.011172375 0.997093916 0.882542572 0.793095486 0.848275004 1.02600844 1.116305974 1 10.19445008 -5.759285109 6.588809174 1.000367205 0.877445079 0.359120587 0.076414369 0.103220697 20.233011 0.009689605 0.018632271 1.74E-06 5.759285109 -0.122922126 AVGAQASVGSRSEGEGEAAS(ph)ADDGSLNTSGAGPK ddPTM_HeLa_Curcumin_4h_R1 1 AVGAQASVGSRSEGEGEAASADDGSLNTSGAGPK 34 1 M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8;M0R2I2 M0QXG9 BABAM1 BRISC and BRCA1-A complex member 1 1 0 AVGAQAS(0.027)VGS(0.286)RS(0.286)EGEGEAAS(0.371)ADDGS(0.028)LNT(0.002)S(0.001)GAGPK 68.368 9.77E-06 8769500 358 357.08 336.86 447.42 404.69 483.97 353.87 471.46 383.78 427.63 TRUE FALSE FALSE 329.6639222 387.9444041 349.3443279 445.5686946 399.8643361 383.5891665 363.7986398 615.2059837 341.6802942 442.4901107 0.745019864 0.876730112 0.789496351 1.006957407 0.903668413 0.866887547 0.822162193 1.39032708 0.772176114 1 8.789501402 -4.257636032 24.75463754 0.877530055 1.390327308 0.774320882 0.08486542 141.8538889 923232.0191 0.014100821 0.141632525 5.53E-05 4.257636032 0.512797253 AVGDGIVLCK ddPTM_HeLa_Curcumin_4h_R1 2 AVGDGIVLCK 10 0 P13797;A0A0A0MSQ0;P13797-3;P13797-2;U3KQI3 P13797 PLS3 Plastin-3 0 0 ; ; 144.12 1.61E-05 10505500 8683.6 6180.1 8696.7 7271.4 7650 11012.5 8226.4 8896.4 7455.3 6578.9 FALSE FALSE TRUE 7996.283897 6714.280306 9019.007352 7241.312873 7558.778746 8728.383364 8457.210644 11608.87141 6637.472242 6807.516285 1.174625746 0.986303965 1.324860195 1.06372318 1.110357791 1.282168562 1.242334251 1.70530204 0.975021133 1 12.73291281 -1.000000001 0.699239353 1.090515904 75.13626843 0.749435028 0.105138338 96.76522447 0.480942295 0.01689603 11216.68134 0.1 1.000000001 74.04575253 AVGK(ac)LTPEHLIK ddPTM_HeLa_Curcumin_4h_R1 1 AVGKLTPEHLIK 12 1 Q96L91-4;Q96L91-3;Q96L91-5;Q96L91-2;Q96L91;A0A0A0MR70 Q96L91-4 EP400 E1A-binding protein p400 0 1 AVGK(1)LTPEHLIK 73.273 0.0092165 0 3101.8 3112.7 3641.2 2789.5 2537 3329 2309.4 2656.3 2919.3 3102.8 FALSE TRUE FALSE 2856.289257 3381.747918 3776.146075 2777.957788 2506.747932 2638.527874 2374.195549 3466.193642 2599.060094 3210.622069 0.889637334 1.053299904 1.176141568 0.865239735 0.780767053 0.821812041 0.739481477 1.079601886 0.809519164 1 11.64863714 -6.026857562 24.94304842 0.973836472 0.84201794 0.20641179 0.12374805 794.0630288 737458.2662 0.017329753 0.028794902 9.40E-07 6.026857562 -0.131818532 AVGK(ac)VIPELNGK ddPTM_HeLa_Curcumin_4h_R1 2 AVGKVIPELNGK 12 1 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 1 ; AVGK(1)VIPELNGK;AVGK(1)VIPELNGK 145.91 7.93E-05 14058000 9457.1 7915.8 8618.3 8397.4 8247.2 12850 9882 10698 9915.6 8440.9 FALSE TRUE FALSE 8708.560556 8600.00648 8937.701779 8362.653784 8148.857526 10184.76515 10159.26232 13959.77095 8827.883488 8734.220647 0.99706212 0.984633527 1.023296999 0.957458498 0.932980498 1.166076009 1.163156134 1.598284669 1.010723663 1 13.09246326 -3.607555994 0.998333894 0.993509593 3.082027904 0.936895299 0.046986271 0.905788685 0.276895348 0.006598724 2.78343356 0.000246856 3.607555994 2.088518311 AVGMPS(ph)PVSPK ddPTM_HeLa_Curcumin_4h_R1 1 AVGMPSPVSPK 11 0 Q9UHB7 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 0 AVGMPS(0.785)PVS(0.215)PK 90.434 0.017008 24901000 6587.5 5321.6 6002.4 5774.6 6166 7667.7 5477.2 3450 6958.1 5552.1 TRUE FALSE FALSE 6066.092424 5781.575391 6224.854224 5750.706235 6092.474477 6077.332587 5630.875491 4501.889118 6194.813838 5745.035062 1.055884317 1.006360332 1.083518927 1.000987143 1.060476466 1.057840818 0.980129004 0.783613863 1.078289997 1 12.48809998 -4.283551227 2.952806046 1.031764603 0.748368278 0.860434698 0.031109272 0.092600076 1.190276746 0.004120287 0.060273245 5.21E-05 4.283551227 -0.283396326 AVGMPSPVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 AVGMPSPVSPK 11 0 Q9UHB7 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 0 AVGMPS(0.325)PVS(0.675)PK;AVGMPS(0.125)PVS(0.875)PK;AVGMPS(0.252)PVS(0.748)PK ;; 158.25 0.0003831 226971000 17640.8 14671.1 15812.9 15452.7 15417.4 16949.8 13445 11432.1 16729.8 14687 TRUE FALSE FALSE 16244.51207 15939.20451 16398.93998 15388.76082 15233.55757 13434.22042 13822.23051 14917.69466 14894.5828 15197.37216 1.068902696 1.048813199 1.079064184 1.012593537 1.002381031 0.883983117 0.909514512 0.981596983 0.980076203 1 13.89153426 -5.475088444 3.427206164 1.036921334 0.923870983 0.622479738 0.036773069 0.11376104 2.682257296 0.005456861 0.012585632 3.35E-06 5.475088444 -0.113050352 TGFGGK(ac)FGVQSER ddPTM_HeLa_Curcumin_4h_R1 2 TGFGGKFGVQSER 13 1 Q14247 Q14247 CTTN Src substrate cortactin 0 1 ; TGFGGK(1)FGVQSER;TGFGGK(1)FGVQSER 148.96 0.00026667 17075700 2063.73 2387.7 1624.76 1746.46 2397.96 2570.6 2150.7 8958.8 2050.01 1768.28 FALSE TRUE FALSE 1900.383593 2594.082149 1684.975035 1739.233611 2369.365893 2037.428583 2211.042854 11690.29688 1825.129032 1829.727598 1.038615581 1.417742264 0.920888463 0.950542372 1.294928215 1.113514703 1.208400013 6.389091409 0.997486748 1 10.83741317 -4.261181042 5.89359026 1.063215414 6.543047957 0.991175044 0.149605351 0.00818166 1.29574984 0.020538102 0.178825826 5.48E-05 4.261181042 5.479832543 up AVIHEMSAQT(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 AVIHEMSAQTGK 12 0 Q5JVX7 Q5JVX7 C1orf141 Uncharacterized protein C1orf141 1 0 AVIHEMS(0.005)AQT(0.995)GK 91.087 0.0053162 0 1987.8 1268.5 1674 1514.4 2046 1870.3 1519.8 1494.8 1492.8 1717.8 TRUE FALSE FALSE 1830.463532 1378.143488 1736.039913 1508.133814 2021.602786 1482.378697 1562.441498 1950.557639 1329.043575 1777.493422 1.029800454 0.775329726 0.976678671 0.848460982 1.137333484 0.833971411 0.879013941 1.097364195 0.747706607 1 10.79562851 AVIVGK(ac)ESK ddPTM_HeLa_Curcumin_4h_R1 1 AVIVGKESK 9 1 Q14004-2;Q14004;A0A2R8Y7W5;A0A2R8Y4Z0;A0A2R8Y7Y0;A0A2R8YCQ1;A0A2R8YD28 Q14004-2 CDK13 Cyclin-dependent kinase 13 0 1 AVIVGK(1)ESK 109.29 0.0037852 1325300 656.17 531.82 599.58 657.11 656.6 1037.3 599.23 679.82 550.02 688.69 FALSE TRUE FALSE 604.2334521 577.7881511 621.8009622 654.3910529 648.7704738 822.1522872 616.0427811 887.0939885 489.6841821 712.6219262 0.847901854 0.810791992 0.87255379 0.918286442 0.910399259 1.15370052 0.864473514 1.244831173 0.687158455 1 9.476993063 -5.285950842 22.78732794 0.91153767 1.065348892 0.362595105 0.124220866 220.0893762 204608.2309 0.014859205 0.033249145 5.18E-06 5.285950842 0.153811223 AVIVSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 AVIVSSPK 8 0 Q14966-3;Q14966;Q14966-5 Q14966-3 ZNF638 Zinc finger protein 638 1 0 AVIVS(0.032)S(0.968)PK;AVIVS(0.014)S(0.986)PK ; 138.08 0.0034447 503710000 20164.2 14202 17257.3 18486.4 17925.2 21485 19683 6021.4 20212.5 16502.1 TRUE FALSE FALSE 18568.18229 15429.5576 17896.87072 18409.90818 17711.4537 17028.76881 20235.25201 7857.297141 17995.23932 17075.54675 1.087413631 0.903605479 1.048099425 1.07814458 1.037240796 0.997260531 1.185042699 0.460149081 1.053860212 1 14.05964415 -4.25254156 24.99989409 1.039766279 0.460148785 0.866750534 0.068593549 292.8163243 822698.4915 0.00908917 0.147698916 5.59E-05 4.25254156 -0.579617494 AVLAAS(ph)S(ph)PYFRDHS(ph)ALSTMSGLSIS(ph)VIK ddPTM_HeLa_Curcumin_4h_R1 1 AVLAASSPYFRDHSALSTMSGLSISVIK 28 1 A0A0C4DFQ2;Q8NCN2 A0A0C4DFQ2 ZBTB34 Zinc finger and BTB domain-containing protein 34 4 0 AVLAAS(0.691)S(0.691)PY(0.306)FRDHS(0.332)ALS(0.317)T(0.317)MS(0.326)GLS(0.049)IS(0.971)VIK 40.142 0.0083208 0 0 87.801 0 197.94 228.78 0 0 176.44 165.09 197.66 TRUE FALSE FALSE 0 95.39012721 0 197.1209767 226.0519479 0 0 230.2357438 146.98004 204.5286703 0 0.466390003 0 0.963781637 1.105233548 0 0 1.12568934 0.718628053 1 7.67615928 -9.611060414 1.435704417 0.997968413 0.386306957 0.085391135 0.454382596 0.548185424 2.039168171 0.317475075 0.074084479 2.45E-10 9.611060414 -0.611661457 SPGS(ph)TPTTPT(ph)SSQAPQK ddPTM_HeLa_Curcumin_4h_R1 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 0 S(0.492)PGS(0.502)T(0.007)PT(0.003)T(0.011)PT(0.821)S(0.141)S(0.024)QAPQK 195.28 4.86E-07 38357000 3266.2 3010.6 3120.7 2940.8 3116.5 4059.8 5235.5 6162.1 3247.2 2657.6 TRUE FALSE FALSE 3007.676824 3270.822849 3236.355887 2928.631749 3079.337773 3217.751717 5382.394039 8040.895923 2890.990284 2749.951402 1.093719991 1.189411146 1.176877484 1.06497582 1.119778979 1.170112211 1.957268785 2.924013827 1.051287773 1 11.42519041 -4.408300667 1.701563951 1.069145445 3.278078347 0.987219019 0.06533584 0.059718961 0.209134773 0.011216372 0.194407913 3.91E-05 4.408300667 2.208932902 up AVLFCLSEDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 AVLFCLSEDKK 11 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 1 AVLFCLSEDK(1)K 182.71 3.03E-12 1044400 427.73 555.03 456.18 275.59 903.04 999.11 810.43 535.44 1362.2 333.29 FALSE TRUE FALSE 393.8747192 603.00432 473.0864321 274.4496816 892.2718378 791.8833237 833.1684846 698.6931911 1212.770068 344.8718027 1.142090238 1.748488323 1.371774753 0.795802033 2.587256571 2.296167206 2.415878823 2.025950471 3.516582274 1 8.429916366 -5.758956999 24.99999023 1.133876702 2.334843356 0.002823903 0.800693764 20.49294505 206379.4765 0.041516 0.080032441 1.74E-06 5.758956999 1.200966654 AVLFCLSEDKK ddPTM_HeLa_Curcumin_4h_R1 4 AVLFCLSEDKK 11 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 0 ;;; ;;; 128.35 0.0002917 206766000 14240.1 10561.7 12108.1 12843.1 12086.6 16357.6 13264 12489.9 13445.5 12126.3 FALSE FALSE TRUE 13112.98106 11474.60629 12556.83684 12789.95866 11942.47519 12964.84937 13636.15214 16298.01301 11970.56229 12547.68802 1.045051569 0.914479725 1.000729124 1.01930799 0.951766984 1.033246073 1.086746189 1.298885738 0.954005413 1 13.61513394 -4.218964202 1.848231766 1.00767361 1.413263075 0.83761041 0.040871095 0.278699419 0.880621529 0.005700679 0.20172822 6.04E-05 4.218964202 0.405589466 AVLLAGPPGTGK ddPTM_HeLa_Curcumin_4h_R1 1 AVLLAGPPGTGK 12 0 Q9Y265;Q9Y265-2;E7ETR0 Q9Y265 RUVBL1 RuvB-like 1 0 0 137.46 0.00021729 1667700 2785.5 2601.9 2918.2 2705.9 2792.4 3796.7 2694.2 2666.6 3243.6 2829.3 FALSE FALSE TRUE 2565.024736 2826.796642 3026.351059 2694.703703 2759.102454 3009.221622 2769.792001 3479.634064 2887.785195 2927.617964 0.876147355 0.965561995 1.03372472 0.920442399 0.942439378 1.027873739 0.946090656 1.188554691 0.986394137 1 11.51551159 -1.729605234 1.288329498 0.949925194 199.9999999 0.621451589 0.049777342 661.7536773 1.676481583 0.008522957 388623.7725 0.018637805 1.729605234 199.0500747 AVLS(ph)DSPQLSEGK ddPTM_HeLa_Curcumin_4h_R1 1 AVLSDSPQLSEGK 13 0 Q5VY60;Q7Z4H7-3;Q7Z4H7;Q5SYF9;Q7Z4H7-2 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 0 AVLS(0.959)DS(0.041)PQLS(0.001)EGK 96.23 0.0089755 78911000 3368.6 2842.2 3485.8 3222.5 2783.1 3478.8 2386.8 1565.2 3191.3 2853.4 TRUE FALSE FALSE 3101.971755 3087.867103 3614.986814 3209.166149 2749.91335 2757.257666 2453.767184 2042.422275 2841.222374 2952.555438 1.050605762 1.045828662 1.224358658 1.086911395 0.93136722 0.933854664 0.831065576 0.691747308 0.962292643 1 11.52774843 -4.637563377 1.096892845 1.043806455 0.639993093 0.729707204 0.071806557 0.408722397 0.588226118 0.011389995 0.16281365 2.30E-05 4.637563377 -0.403813362 AVLSAEQLRDEEVHAGLGELLR ddPTM_HeLa_Curcumin_4h_R1 2 AVLSAEQLRDEEVHAGLGELLR 22 1 P50454;E9PR70;E9PPV6;E9PK86;E9PMI5;E9PQ34;E9PJH8;E9PIG2;E9PRS3;E9PNX1 P50454 SERPINH1 Serpin H1 0 0 ; ; 79.695 0.00040575 54826000 6778.4 5445 5893.9 6181.9 6373 6962.6 4419.8 3957.3 7225.3 6112 FALSE FALSE TRUE 6241.882487 5915.641538 6112.333119 6156.320936 6297.006137 5518.478275 4543.807693 5163.862553 6432.702667 6324.391545 0.986953835 0.935369276 0.966469751 0.973425015 0.995669875 0.872570624 0.718457683 0.816499503 1.017125936 1 12.62671097 -5.03751184 3.284254364 0.985454111 0.768393073 0.883099872 0.031372045 0.049705482 1.082926748 0.004200986 0.012984157 9.17E-06 5.03751184 -0.217061038 AVLSDS(ph)PQLSEGK ddPTM_HeLa_Curcumin_4h_R1 2 AVLSDSPQLSEGK 13 0 Q5VY60;Q7Z4H7-3;Q7Z4H7;Q5SYF9;Q7Z4H7-2 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 0 AVLSDS(0.975)PQLS(0.025)EGK;AVLS(0.078)DS(0.922)PQLSEGK ; 201.3 8.65E-09 8838200 4487 3983.7 4030.7 4254.1 3751.1 5095.3 3623.7 1878.48 4848.4 3565.1 TRUE FALSE FALSE 4131.849215 4328.033277 4180.081288 4236.497661 3706.370582 4038.477344 3725.371269 2451.219905 4316.54265 3688.98696 1.12004983 1.173230842 1.133124441 1.14841763 1.004712303 1.094738851 1.009862954 0.664469658 1.170115996 1 11.84900897 -4.256707595 2.930941555 1.076388456 0.591445495 0.808028113 0.063171849 0.147612308 1.783830627 0.009643411 0.169014526 5.54E-05 4.256707595 -0.484942961 AVLVDLEPGTMDS(ph)VR ddPTM_HeLa_Curcumin_4h_R1 1 AVLVDLEPGTMDSVR 15 0 P04350;M0R0X0;M0QY85;M0QY37;M0QX14;M0QZL7;M0R278;A0A075B724;P68371;Q3ZCM7 P04350;P68371 TUBB4A;TUBB8;TUBB4B Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-8 chain 1 0 AVLVDLEPGT(0.103)MDS(0.897)VR 98.654 0.0051578 2787800 1954.7 2045.1 2001.9 1761 1715.5 2949.5 2129.7 1659.3 2335 1846.3 TRUE FALSE FALSE 1799.983432 2221.869331 2076.092175 1753.713449 1695.043783 2337.740452 2189.45365 2165.212932 2078.856342 1910.458788 0.94217339 1.163003016 1.086698226 0.917954085 0.887244359 1.223653956 1.146035531 1.133347103 1.088145086 1 10.89970342 -5.253337462 24.97334314 0.986374527 1.165514534 0.386912265 0.085476102 393.6676538 1213436.993 0.011869161 0.029695774 5.58E-06 5.253337462 0.179140008 AVNSLRDFVDDDDDDDLER ddPTM_HeLa_Curcumin_4h_R1 2 AVNSLRDFVDDDDDDDLER 19 1 G3V4K3;Q9H9C1-2;Q9H9C1 G3V4K3 VIPAS39 Spermatogenesis-defective protein 39 homolog 0 0 ; ; 110.77 0.00040162 6840200 2695 2089.46 2142.53 3088.9 2427.65 2327 2117.55 1907.12 3200.1 2565 FALSE FALSE TRUE 2481.687906 2270.063612 2221.934047 3076.11895 2398.701859 1844.353969 2176.962754 2488.592109 2849.057036 2654.133559 0.935027515 0.855293662 0.837159848 1.15899177 0.903760796 0.694898704 0.820215978 0.937628817 1.073441473 1 11.37402526 -1.017520431 0.068012429 1.138146776 0.372240249 0.211002498 0.112184766 331.6483474 1.691792412 3.512729217 24.60565365 0.096046063 1.017520431 -0.765906527 AVNTQALS(ph)GAGILR ddPTM_HeLa_Curcumin_4h_R1 2 AVNTQALSGAGILR 14 0 O60749-2;O60749 O60749-2 SNX2 Sorting nexin-2 1 0 AVNT(0.002)QALS(0.998)GAGILR;AVNTQALS(1)GAGILR ; 147.51 0.00057628 22872000 2399 2137.13 2341.48 2615.7 2406.4 3833.4 4633.9 2689.04 2773.07 2483.87 TRUE FALSE FALSE 2209.116619 2321.853994 2428.257309 2604.876926 2377.705252 3038.309629 4763.914762 3508.915917 2468.871159 2570.184298 0.859516814 0.903380352 0.944779451 1.013498109 0.9251108 1.182136873 1.853530413 1.36523903 0.960581372 1 11.3276561 -4.95860057 4.593010768 0.939212128 1.605474395 0.83137579 0.118516889 0.049666951 2.370160754 0.015637563 0.048675131 1.10E-05 4.95860057 0.666262267 AVPETEDVQASVSDTAQQPSEEQSKS(ph)LEKPK ddPTM_HeLa_Curcumin_4h_R1 1 AVPETEDVQASVSDTAQQPSEEQSKSLEKPK 31 2 Q6FIF0-2;Q6FIF0;H0YME2;H0YK21;H0YK54 Q6FIF0-2 ZFAND6 AN1-type zinc finger protein 6 1 0 AVPETEDVQASVS(0.008)DT(0.028)AQQPS(0.071)EEQS(0.187)KS(0.706)LEKPK 77.802 3.25E-06 13176000 1525.4 1197 1290.6 1374.3 1596.4 2076.7 1641.2 899.47 1528.2 1331.4 TRUE FALSE FALSE 1404.66298 1300.463346 1338.430771 1368.613511 1577.363973 1645.969011 1687.247655 1173.714262 1360.560283 1377.666051 1.019596135 0.943961235 0.971520471 0.993429075 1.144953795 1.194751812 1.224714548 0.851958471 0.987583517 1 10.4280105 -5.767124459 24.93942858 0.999894669 1.119185879 0.251504769 0.096662383 131.2804837 575906.8813 0.013302006 0.024601798 1.71E-06 5.767124459 0.119291209 AVPMAPAPAS(ph)PGSSNDSSAR ddPTM_HeLa_Curcumin_4h_R1 7 AVPMAPAPASPGSSNDSSAR 20 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 0 AVPMAPAPAS(0.975)PGS(0.018)S(0.006)NDS(0.001)S(0.001)AR;AVPMAPAPAS(0.824)PGS(0.133)S(0.042)NDS(0.001)SAR;AVPMAPAPAS(0.91)PGS(0.068)S(0.022)NDSSAR;AVPMAPAPAS(0.99)PGS(0.008)S(0.002)NDSSAR;AVPMAPAPAS(0.959)PGS(0.012)S(0.012)NDS(0.009)S(0.009)AR;AVPMAPAPAS(0.991)PGS(0.007)S(0.002)NDSSAR;AVPMAPAPAS(0.996)PGS(0.004)SNDSSAR ;;;;;; 247.28 3.27E-34 443152800 12566.18 10245.58 10801.59 11473.8 11491.2 11824.26 9666.5 8705.35 12111.44 10946.46 TRUE FALSE FALSE 11571.55359 11131.16228 11201.90643 11426.32446 11354.17495 9371.775189 9937.715974 11359.57114 10782.84533 11326.84867 1.021603972 0.982723669 0.988969373 1.0087823 1.002412522 0.827394756 0.877359296 1.00288893 0.951972225 1 13.46745891 -5.345080075 9.689145761 1.006194752 0.900117971 0.444860704 0.045220537 0.228497362 25.26099379 0.005701806 0.012763066 4.52E-06 5.345080075 -0.10607678 AVPMLTPKPYS(ph)QPK ddPTM_HeLa_Curcumin_4h_R1 1 AVPMLTPKPYSQPK 14 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 AVPMLT(0.001)PKPY(0.018)S(0.981)QPK 64.52 0.018257 15223000 1814.1 1569.5 1464.1 1656.6 1523.3 2930.3 2883 1209.9 1955.5 1455.3 TRUE FALSE FALSE 1670.512071 1705.160586 1518.360834 1649.745428 1505.135642 2322.522749 2963.889221 1578.79294 1740.986542 1505.871567 1.109332368 1.132341313 1.008293713 1.09554192 0.999511297 1.54231131 1.968221784 1.048424697 1.156132157 1 10.55638301 -5.255442727 22.58028953 1.055985077 1.564509718 0.474304707 0.214170128 66.09658811 248880.3814 0.026575809 0.065655532 5.55E-06 5.255442727 0.508524641 AVPPVS(ph)PELR ddPTM_HeLa_Curcumin_4h_R1 4 AVPPVSPELR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 AVPPVS(1)PELR;AVPPVS(1)PELR;AVPPVS(1)PELR;AVPPVS(1)PELR ;;; 144.7 0.0011871 495967000 27312.2 23591.9 24982.2 26210.3 26176 30739 21793.6 16861.4 27277.2 25376.9 TRUE FALSE FALSE 25150.41055 25631.07871 25908.06231 26101.84872 25863.8683 24363.3849 22405.06976 22002.36324 24284.9594 26258.74539 0.957791783 0.976096852 0.986645094 0.994024975 0.984962073 0.927819838 0.853242203 0.837906112 0.924833195 1 14.68051037 -4.890479368 2.255669389 0.981238681 0.837893959 0.855362142 0.020995324 0.060714126 0.599974773 0.002407723 0.010431554 1.29E-05 4.890479368 -0.143344721 AVPSQK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 AVPSQKR 7 1 P31949 P31949 S100A11 "Protein S100-A11;Protein S100-A11, N-terminally processed" 0 1 AVPSQK(1)R 91.626 0.0098181 1389400 965.5 497.69 957.97 444.77 891.43 946.64 813.34 911.94 774.46 821.84 FALSE TRUE FALSE 889.0796562 540.7081059 993.4732109 442.9296596 880.8002795 750.2961932 836.1601314 1189.986308 689.5036756 850.3988788 1.045485452 0.635828809 1.168243792 0.520849299 1.035749578 0.882287373 0.98325639 1.399327231 0.810800311 1 9.731995885 -4.263384403 5.376188791 0.961711588 1.416034615 0.32983413 0.196541698 0.13142546 13.84522976 0.024650525 0.219207185 5.45E-05 4.263384403 0.454323026 AVPSS(ph)PAGSAAR ddPTM_HeLa_Curcumin_4h_R1 2 AVPSSPAGSAAR 12 0 F8WBN8;B0QYH1;Q8IWD4-4;Q8IWD4-3;Q8IWD4 F8WBN8 CCDC117 Coiled-coil domain-containing protein 117 1 0 AVPS(0.079)S(0.921)PAGSAAR;AVPS(0.23)S(0.769)PAGS(0.001)AAR ; 141.34 0.0011233 149823000 7358.8 6367.4 6920.9 6647.6 6598.3 8127.7 6625.4 4093.9 7421.6 5645.9 TRUE FALSE FALSE 6776.343215 6917.769683 7177.394642 6620.093993 6519.619582 6441.923402 6811.290893 5342.111264 6607.469048 5842.094605 1.159916721 1.184124899 1.228565288 1.133171309 1.115972955 1.102673585 1.165898766 0.91441711 1.131010279 1 12.51227001 -1.004527882 11.96800692 1.099115294 0.002039664 0 0.088629558 0 0 0.012929946 0 0.098962833 1.004527882 -1.097075631 AVPTDEAR ddPTM_HeLa_Curcumin_4h_R1 2 AVPTDEAR 8 0 B4DQU5;H3BMH2;H3BSC1;P62491-2;Q15907-2;P62491;Q15907;M0R377;M0R2D0;H3BN38 B4DQU5 RAB11A;RAB11B Ras-related protein Rab-11A;Ras-related protein Rab-11B 0 0 ; ; 100.19 0.013245 1855480 1855.16 1435.5 1628.35 2106.64 2130.3 3018.8 2056.69 1910.29 2162.3 2417 FALSE FALSE TRUE 1708.322128 1559.578224 1688.698083 2097.923282 2104.897564 2392.666851 2114.395186 2492.728627 1925.1011 2500.99057 0.683058205 0.623584208 0.675211696 0.838836942 0.84162555 0.956687674 0.845423094 0.996696532 0.769735449 1 11.2882839 -5.437355183 3.358588055 0.813056622 0.924172202 0.257960717 0.110483636 0.48841502 10.4750374 0.022328564 0.052617585 3.65E-06 5.437355183 0.11111558 AVPVES(ph)PVQKV ddPTM_HeLa_Curcumin_4h_R1 1 AVPVESPVQKV 11 1 Q8TB61-5;Q8TB61-4;Q8TB61-3;Q8TB61-2;Q8TB61 Q8TB61-5 SLC35B2 Adenosine 3-phospho 5-phosphosulfate transporter 1 1 0 AVPVES(1)PVQKV 103.43 0.01439 21539000 4215.9 3731 3745.5 4631.1 3317.4 4897.5 3614.7 2292.8 5400.5 4498.8 TRUE FALSE FALSE 3882.207066 4053.491015 3884.311525 4611.937735 3277.842172 3881.703294 3716.118754 2991.864165 4808.078661 4655.132965 0.833962659 0.870757301 0.834414732 0.990720946 0.704135026 0.83385444 0.798284127 0.642702193 1.03285528 1 12.18460666 -5.713900981 0.039074479 1.617128146 1.16E-12 0.593484577 0.076425164 110.201173 1.239592235 21.94375667 29.49939565 1.93E-06 5.713900981 -1.617128146 AVQAQGGESQQEAQR ddPTM_HeLa_Curcumin_4h_R1 1 AVQAQGGESQQEAQR 15 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6;Q14980-4;Q14980-3;K4DIE0 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 0 0 122.64 1.05E-05 0 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 AVQEVHPS(ph)PVSR ddPTM_HeLa_Curcumin_4h_R1 2 AVQEVHPSPVSR 12 0 Q9Y4X4;Q9Y4X4-3 Q9Y4X4 KLF12 Krueppel-like factor 12 1 0 AVQEVHPS(0.839)PVS(0.161)R;AVQEVHPS(0.938)PVS(0.062)R ; 84.195 0.0097676 15178800 4272.7 3343.9 3383.1 3704.7 3787.5 5870.4 5116.3 1886.49 4753.9 3208.5 TRUE FALSE FALSE 3934.511286 3632.931816 3508.480662 3689.370933 3742.336536 4652.812867 5259.849608 2461.672117 4232.409064 3319.995136 1.185095497 1.094258174 1.056772832 1.111257933 1.127211451 1.401451712 1.584294372 0.741468591 1.274823875 1 11.69696541 -5.438467775 6.953341046 1.090076643 1.276283604 0.046311105 0.212003782 0.369552178 26.11645132 0.027433366 0.061557529 3.64E-06 5.438467775 0.18620696 AVQQHQHGYDS(ph)DEEVDSELGTWEHQLR ddPTM_HeLa_Curcumin_4h_R1 3 AVQQHQHGYDSDEEVDSELGTWEHQLR 27 0 Q8IWZ8 Q8IWZ8 SUGP1 SURP and G-patch domain-containing protein 1 1 0 AVQQHQHGY(0.134)DS(0.866)DEEVDSELGTWEHQLR;AVQQHQHGY(0.46)DS(0.536)DEEVDS(0.003)ELGTWEHQLR;AVQQHQHGY(0.021)DS(0.978)DEEVDS(0.001)ELGTWEHQLR ;; 115.84 2.23E-09 62209500 2424.99 1894.72 2326.5 2064.93 2592.27 3091.04 2231.92 2103.96 2832.53 2002.55 TRUE FALSE FALSE 2233.049483 2058.491154 2412.722137 2056.385867 2561.358873 2449.923461 2294.541668 2745.447719 2521.808546 2072.138463 1.077654569 0.993413901 1.164363376 0.992397903 1.236094459 1.182316483 1.107330282 1.32493449 1.217007739 1 11.01690469 -1 0.219966711 1.006892115 2.397293556 0.231632523 0.095415192 25.9819501 0.310792751 0.04936858 12.94569748 0.1 1 1.390401442 LQQQAALSPT(ph)TAPAVSSVSK ddPTM_HeLa_Curcumin_4h_R1 2 LQQQAALSPTTAPAVSSVSK 20 0 A0A0U1RRM1;Q8WXI9;A0A0U1RR30 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 0 LQQQAALS(0.134)PT(0.681)T(0.185)APAVSSVSK;LQQQAALS(0.225)PT(0.467)T(0.309)APAVSSVSK ; 216.32 3.39E-18 63304000 6347.7 4826.7 5243.5 6133.8 5533 9983.9 9525.2 10308.2 6499.5 5482.4 TRUE FALSE FALSE 5845.272847 5243.898441 5437.828723 6108.419961 5467.022589 7913.126598 9792.451476 13451.12273 5786.521111 5672.912992 1.030382954 0.924374911 0.958560219 1.076769548 0.963706406 1.394896521 1.72617692 2.371113879 1.020026417 1 12.46987402 -4.407592014 1.134125402 1.000360645 2.813014789 0.981013879 0.061174496 0.110691226 0.1364255 0.008835865 0.22281396 3.91E-05 4.407592014 1.812654144 up GPAFNMASPES(ph)DFGINLK ddPTM_HeLa_Curcumin_4h_R1 2 GPAFNMASPESDFGINLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GPAFNMAS(0.104)PES(0.896)DFGINLK;GPAFNMAS(0.498)PES(0.502)DFGINLK ; 101.53 0.0013096 289300000 6107.6 4516.5 4633 6303.8 5887.3 11468.8 10450 11363.1 6095.6 4901.5 TRUE FALSE FALSE 5624.177015 4906.886135 4804.703056 6277.716546 5817.097793 9090.0416 10743.19888 14827.65688 5426.92793 5071.82676 1.108905584 0.96747905 0.947331856 1.237762416 1.146943314 1.792261848 2.118210929 2.923533784 1.070014452 1 12.30828975 -4.403526847 0.867048628 1.03532913 3.707188796 0.976579401 0.094550394 0.179991929 0.113958605 0.01466056 0.434204957 3.95E-05 4.403526847 2.671859666 up AVS(ph)PAPQSSSR ddPTM_HeLa_Curcumin_4h_R1 2 AVSPAPQSSSR 11 0 Q9P275;A0A075B784 Q9P275 USP36 Ubiquitin carboxyl-terminal hydrolase 36;Ubiquitin carboxyl-terminal hydrolase 1 0 AVS(1)PAPQSSSR;AVS(1)PAPQSSSR ; 164.22 3.91E-09 0 4330 3608 3734.8 3916.4 4281.6 4145.7 2844.8 1826.62 4439.6 3780.7 TRUE FALSE FALSE 3987.275931 3919.859443 3873.214973 3900.194975 4230.544716 3285.835088 2924.617432 2383.548029 3952.586987 3912.079044 1.01922172 1.001988814 0.990065622 0.996962211 1.081405736 0.839920424 0.747586488 0.609279108 1.010354582 1 11.9337198 -4.815524256 1.803730226 1.010546992 0.626625291 0.933479767 0.036453291 0.062155209 0.364881871 0.004818452 0.028100243 1.53E-05 4.815524256 -0.383921701 ASAGRLT(ph)PESQSK ddPTM_HeLa_Curcumin_4h_R1 1 ASAGRLTPESQSK 13 1 J3KQV8;O43426;A0A0D9SGJ6;C9JFZ1;O43426-4;O43426-2;J3KPK1;H7BZ56;H7BZC2 J3KQV8 SYNJ1 Synaptojanin-1 1 0 ASAGRLT(0.892)PES(0.052)QS(0.056)K 135.14 0.012559 4185000 1874.1 1455.7 1885.1 1544.7 1494.7 1558.8 838.97 517.39 1532.8 1602.6 TRUE FALSE FALSE 1725.763007 1581.524222 1954.963464 1538.308441 1476.876679 1235.487309 862.5092402 675.1398292 1364.655675 1658.290231 1.040688159 0.953707736 1.178903082 0.927647291 0.89060205 0.745036837 0.520119593 0.407130077 0.822929334 1 10.69548081 -4.906566655 1.070680786 1.024087017 0.343750901 0.845829647 0.087987565 0.128762799 0.212868419 0.008970241 0.076504555 1.24E-05 4.906566655 -0.680336116 down IIEDGDGAGAET(ph)PVIENR ddPTM_HeLa_Curcumin_4h_R1 2 IIEDGDGAGAETPVIENR 18 0 A0A5H1ZRS1;Q15154-5 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 0 IIEDGDGAGAET(1)PVIENR;IIEDGDGAGAET(1)PVIENR ; 212.35 8.08E-13 33127000 6716 6178.3 5723 6518.2 5194.9 5117.7 1436.22 586.27 7990.8 6394.4 TRUE FALSE FALSE 6184.421513 6712.324722 5935.099414 6491.229415 5132.95421 4056.231332 1476.516468 765.0210241 7114.229232 6616.604924 0.934681998 1.014466603 0.897000725 0.981051384 0.775768581 0.613038164 0.223153186 0.115621385 1.075208406 1 12.69187542 -4.900204938 1.165928328 0.969632587 0.021668811 0.970917575 0.055129238 0.058507301 0.120151567 0.006467512 0.050936589 1.26E-05 4.900204938 -0.947963776 down AVS(ph)PPHLDGPPSPR ddPTM_HeLa_Curcumin_4h_R1 3 AVSPPHLDGPPSPR 14 0 P29590;P29590-5;P29590-4;P29590-9;P29590-3;P29590-8;P29590-11;H3BVD2;P29590-12;H3BT57;P29590-13;H3BRN3;H3BUJ5;P29590-2 P29590;P29590-2 PML Protein PML 1 0 AVS(1)PPHLDGPPSPR;AVS(1)PPHLDGPPSPR;AVS(1)PPHLDGPPSPR ;; 84.403 0.0071261 16541500 7023.7 6644.4 6496.2 7391.4 7581.3 7615 5713.8 2693.21 8085.4 6287.4 TRUE FALSE FALSE 6467.766734 7218.712329 6736.954887 7360.816345 7490.897949 6035.563161 5874.11385 3514.357331 7198.451849 6505.886682 0.994140699 1.109566256 1.035516789 1.131408631 1.151403078 0.927708006 0.902892125 0.540181147 1.10645208 1 12.66752998 -4.138791638 1.581319533 1.026353997 0.249043261 0.832282187 0.069728859 0.46024055 0.848646654 0.010427615 0.600896172 7.26E-05 4.138791638 -0.777310736 GQVS(ph)ESEDSITK ddPTM_HeLa_Curcumin_4h_R1 1 GQVSESEDSITK 12 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 0 GQVS(0.537)ES(0.15)EDS(0.312)IT(0.001)K 100.73 0.0088928 6350900 2459.7 2199.3 2096.6 2830.6 2566 2485.9 890.05 922.93 2914.2 2346.1 TRUE FALSE FALSE 2265.01215 2389.397692 2174.30184 2818.887727 2535.402126 1970.296318 915.0224076 1204.327108 2594.519551 2427.6268 0.933014971 0.984252477 0.895649134 1.16117013 1.044395343 0.811614173 0.376920541 0.49609236 1.068747285 1 11.24533094 -4.899543755 3.724546137 0.981466709 0.436386238 0.888170109 0.080195861 0.049022347 1.290832823 0.010836702 0.036590942 1.26E-05 4.899543755 -0.545080471 down AVSDWIDEQEKGSSEQAES(ph)DNMDVPPEDDSKEGAGEQK ddPTM_HeLa_Curcumin_4h_R1 1 AVSDWIDEQEKGSSEQAESDNMDVPPEDDSKEGAGEQK 38 2 Q12906;Q12906-7;Q12906-5;Q12906-4;Q12906-2;Q12906-6;Q12906-3;K7EKJ9;K7ER69;K7EM82;K7EJ09 Q12906 ILF3 Interleukin enhancer-binding factor 3 1 0 AVS(0.001)DWIDEQEKGS(0.101)S(0.101)EQAES(0.797)DNMDVPPEDDSKEGAGEQK 83.562 6.31E-10 7751500 2599.7 1879.4 2005.4 1976.8 2537.4 2466.2 2146.3 2034.6 2175.8 2061.9 TRUE FALSE FALSE 2393.931002 2041.846962 2079.721888 1968.620525 2507.143162 1954.68232 2206.519402 2654.940174 1937.120184 2133.550872 1.122040741 0.957018175 0.974770237 0.922696783 1.175103531 0.916163915 1.034200511 1.244376316 0.907932503 1 11.05904079 -4.261339769 20.98658643 1.034705741 1.244376823 0.34775369 0.089911586 0.746974968 154717.4146 0.011568206 0.089285468 5.48E-05 4.261339769 0.209671082 AVSETPAVPPVS(ph)EDEDDDDDDATPPPVIAPRPEHTK ddPTM_HeLa_Curcumin_4h_R1 2 AVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTK 36 1 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 0 AVSET(0.008)PAVPPVS(0.984)EDEDDDDDDAT(0.008)PPPVIAPRPEHTK;AVS(0.001)ET(0.013)PAVPPVS(0.52)EDEDDDDDDAT(0.466)PPPVIAPRPEHT(0.001)K ; 76.063 1.06E-06 52626000 5173.9 4305.6 4455.1 4731 5290.1 6301.9 4257.8 3938.1 5845.9 4573.1 TRUE FALSE FALSE 4764.380356 4677.756879 4620.209925 4711.424376 5227.019013 4994.814903 4377.262409 5138.808561 5204.619396 4732.014885 1.006839681 0.988533847 0.976372653 0.99564868 1.104607475 1.0555366 0.925031412 1.085966272 1.099873843 1 12.2082389 ENQECPRS(ph)LEEDLETLK ddPTM_HeLa_Curcumin_4h_R1 2 ENQECPRSLEEDLETLK 17 1 P48681 P48681 NES Nestin 1 0 ENQECPRS(1)LEEDLETLK;ENQECPRS(0.989)LEEDLET(0.011)LK ; 100.9 0.00087927 80587000 3521.3 3087.9 2615.7 3261.1 2588.5 3960.8 5931.2 7769.4 3548.4 3153.4 TRUE FALSE FALSE 3242.585389 3354.804317 2712.640143 3247.606432 2557.633828 3139.285433 6097.613509 10138.25429 3159.149398 3262.980415 0.993749571 1.028141113 0.831338163 0.995288362 0.783833644 0.962091411 1.868725133 3.10705337 0.968179086 1 11.67197461 -4.40139513 2.118456285 0.967452822 3.370361636 0.982298955 0.090514675 0.046627643 0.286685871 0.013773676 0.189197068 3.97E-05 4.40139513 2.402908814 up SISSS(ph)NPDLAVAPGSVDDEVSR ddPTM_HeLa_Curcumin_4h_R1 1 SISSSNPDLAVAPGSVDDEVSR 22 0 K7EKT0;K7EP20;K7ESB7;Q96HP0 K7EKT0 DOCK6 Dedicator of cytokinesis protein 6 1 0 SIS(0.024)S(0.222)S(0.753)NPDLAVAPGSVDDEVSR 287.48 2.26E-87 25838000 1185.4 1322.1 1453.8 1414.2 1358.7 1185.7 543.56 284.37 1482.8 1462 TRUE FALSE FALSE 1091.574339 1436.376433 1507.679107 1408.348415 1342.49839 939.7724544 558.8108307 371.0731039 1320.14055 1512.804391 0.721556829 0.949479286 0.996612064 0.930952094 0.887423647 0.621212141 0.369387367 0.245288225 0.872644578 1 10.56300974 -4.89731393 1.88850291 0.888814318 0.25545582 0.905985828 0.077924319 0.113862785 0.760386026 0.016592791 0.081492689 1.27E-05 4.89731393 -0.633358498 down S(ph)KTPTGPELDTSYK ddPTM_HeLa_Curcumin_4h_R1 1 SKTPTGPELDTSYK 14 1 Q8NF91;Q8NF91-4;A0A0C4DG40;E7ENN3;Q8NF91-11;H0Y325;A0A5F9ZH87;F8WAI0;Q5JV20;A0A5F9ZHE1;H0Y326;A0A5F9ZH86;Q8NF91-3;Q8NF91-9;Q8NF91-8;Q8NF91-2 Q8NF91 SYNE1 Nesprin-1 1 0 S(0.976)KT(0.024)PTGPELDTSYK 86.944 0.0055796 15488000 1879.4 1451.7 1694.2 2038.5 1495.7 1706.6 1047.6 624.55 2185.9 1709.6 TRUE FALSE FALSE 1730.643507 1577.178479 1756.988542 2030.065227 1477.864754 1352.631923 1076.992837 814.9724199 1946.112239 1769.008473 0.978312729 0.891560727 0.993205273 1.14757236 0.835419828 0.764627159 0.608811576 0.46069447 1.100114708 1 10.78872524 -4.895482185 1.266949817 0.990489445 0.450489202 0.854971922 0.078201922 0.146059315 0.370372703 0.010435856 0.075828547 1.27E-05 4.895482185 -0.540000244 down AVSTVVVTT(ph)APSPK ddPTM_HeLa_Curcumin_4h_R1 1 AVSTVVVTTAPSPK 14 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 0 AVSTVVVT(0.042)T(0.92)APS(0.037)PK 153.14 0.0012745 75255000 4850.8 4274.5 4382.5 4670.1 4125.4 5047.6 4968.1 2554.6 5045 5090.2 TRUE FALSE FALSE 4466.854061 4643.968733 4544.919305 4650.776364 4076.207299 4000.670862 5107.491515 3333.48578 4491.576122 5267.084071 0.848069634 0.881696337 0.862890974 0.882988823 0.773902076 0.759560851 0.969700017 0.632890179 0.852763324 1 12.36278877 -13.52287875 0.11182314 1.582137005 0.7222724 0.17460137 0.090887362 66.77960876 0.546930201 8.874812311 0.439041796 3.00E-14 13.52287875 -0.859864605 AVSTVVVTTAPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 AVSTVVVTTAPSPK 14 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 0 AVSTVVVT(0.001)T(0.109)APS(0.89)PK 234.66 6.88E-21 63898000 4835.6 3515.8 3855.7 3843.5 3641.6 4080.3 3332.4 2320.9 4592.2 3218.4 TRUE FALSE FALSE 4452.857157 3819.690086 3998.595634 3827.596615 3598.176298 3233.999786 3425.898175 3028.531726 4088.447149 3330.23916 1.337098311 1.146971704 1.200693236 1.149345867 1.080455825 0.971101362 1.028724368 0.909403673 1.227673735 1 11.70141007 -5.473492437 1.951410566 1.16549703 0.969514803 0.552074935 0.083440749 0.322131663 2.402401689 0.018960823 0.050896702 3.36E-06 5.473492437 -0.195982227 KASS(ph)PSPLT(ph)IGTPESQR ddPTM_HeLa_Curcumin_4h_R1 1 KASSPSPLTIGTPESQR 17 1 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 2 0 KAS(0.18)S(0.816)PS(0.48)PLT(0.513)IGT(0.01)PESQR 120.59 0.00097539 13735000 2121.9 1565.3 2074.2 1834.7 1829.1 1694.6 788.29 497.72 2544.4 2123.4 TRUE FALSE FALSE 1953.949376 1700.597557 2151.071677 1827.108498 1807.289177 1343.120858 810.4072958 649.4725368 2265.285686 2197.187992 0.889295492 0.77398819 0.979011211 0.831566759 0.822546447 0.611290824 0.368838397 0.295592612 1.030993112 1 11.1014426 -4.88738711 0.922492161 0.935835081 0.171024061 0.917716737 0.070014178 0.189882691 0.210561688 0.011356643 0.11669449 1.30E-05 4.88738711 -0.76481102 down SVCPGGSS(ph)PGSSS(ph)GGGR ddPTM_HeLa_Curcumin_4h_R1 1 SVCPGGSSPGSSSGGGR 17 0 Q53LP3 Q53LP3 SOWAHC Ankyrin repeat domain-containing protein SOWAHC 2 0 SVCPGGS(0.435)S(0.564)PGS(0.001)S(0.043)S(0.957)GGGR 93.909 0.0079516 11165000 4432.1 4252 4212.7 4890.5 3944.2 3887.2 2653.4 1312.2 5277.4 4529.7 TRUE FALSE FALSE 4081.294608 4619.523933 4368.826368 4870.264407 3897.167991 3080.950902 2727.847263 1712.283739 4698.482423 4687.106738 0.870749235 0.985581125 0.932094491 1.039076914 0.831465595 0.657324673 0.581989576 0.365317846 1.002427017 1 12.19448193 -4.879759794 1.162730101 0.948045413 0.359505364 0.920358649 0.059583703 0.153623386 0.309565395 0.010215277 0.083674415 1.32E-05 4.879759794 -0.588540049 down AQS(ph)PGAVEEILDR ddPTM_HeLa_Curcumin_4h_R1 2 AQSPGAVEEILDR 13 0 H7BXT7;E9PHY4;A0A0C4DH16;B8ZZS0;Q9NYM9 H7BXT7 BET1L BET1-like protein 1 0 AQS(1)PGAVEEILDR;AQS(1)PGAVEEILDR ; 128.71 0.0017388 16404100 3771.7 3786.3 3424.6 3764.7 3459.7 3274.7 2061.61 1168.87 3693.4 3148 TRUE FALSE FALSE 3473.165965 4113.570901 3551.518689 3749.122669 3418.445337 2595.490307 2119.453228 1525.253082 3288.24326 3257.392766 1.066241075 1.262841541 1.09029489 1.150958125 1.049442171 0.796799924 0.650659402 0.468243528 1.009470916 1 11.66950197 -4.879540906 1.626738144 1.065931295 0.488470492 0.88319585 0.078853731 0.120906125 0.567056434 0.01311035 0.07575792 1.32E-05 4.879540906 -0.577460803 down AVTELNEPLSNEDR ddPTM_HeLa_Curcumin_4h_R1 2 AVTELNEPLSNEDR 14 0 Q04917 Q04917 YWHAH 14-3-3 protein eta 0 0 ; ; 202 5.18E-08 14598300 3833.5 3454.5 3407.6 4001.7 4589.9 4853.6 3629.2 2856.3 4202.4 3812.7 FALSE FALSE TRUE 3530.07443 3753.091587 3533.888654 3985.142026 4535.16844 3846.908649 3731.025585 3727.172721 3741.407234 3945.191041 0.894779085 0.951307946 0.895745888 1.010126502 1.14954343 0.975088052 0.945714807 0.94473821 0.948346276 1 11.94587945 -6.224785605 23.61918877 0.945420293 1.008109992 0.227345738 0.060878013 436.8658506 281509.7261 0.010467467 0.017357763 5.96E-07 6.224785605 0.062689699 AVTEQGAELSNEER ddPTM_HeLa_Curcumin_4h_R1 3 AVTEQGAELSNEER 14 0 P27348;E9PG15 P27348 YWHAQ 14-3-3 protein theta 0 0 ;; ;; 291.22 2.31E-112 52780000 5333.4 5313.6 4649.3 5154.2 4643.4 5859.8 4985.1 4890.8 6199.7 4673 FALSE FALSE TRUE 4911.255762 5772.883907 4821.607148 5132.873286 4588.030488 4644.411426 5124.968489 6381.982406 5519.608421 4835.386402 1.015690444 1.193882645 0.99715033 1.061522877 0.948844644 0.960504713 1.059888096 1.319849517 1.14150307 1 12.23941547 -4.274719744 3.738718578 1.017096157 1.347687132 0.53294121 0.075758492 0.111862029 2.955773845 0.008834806 0.099824447 5.31E-05 4.274719744 0.330590975 AVTEQGHELSNEER ddPTM_HeLa_Curcumin_4h_R1 4 AVTEQGHELSNEER 14 0 P31946-2;P31946;Q4VY20;Q4VY19;A0A0J9YWE8;A0A0J9YWZ2 P31946-2 YWHAB "14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed" 0 0 ;;; ;;; 276.32 4.43E-63 148376000 11826.9 11440.1 11483.2 10307.3 12627.1 16631.1 11630.7 10739.2 12996.8 11865 FALSE FALSE TRUE 10890.78839 12428.93127 11908.77749 10264.65112 12476.53008 13181.62239 11957.02614 14013.53264 11571.08356 12277.30787 0.887066489 1.01234989 0.969982803 0.836066932 1.016226865 1.073657396 0.973912707 1.141417385 0.942477266 1 13.58370662 -5.534550161 24.97034131 0.945140438 1.052563303 0.44361934 0.061600695 172.7074802 369497.3475 0.009457877 0.018927091 2.92E-06 5.534550161 0.107422865 LQALVNSLCAGQS(ph)P ddPTM_HeLa_Curcumin_4h_R1 1 LQALVNSLCAGQSP 14 0 Q6XQN6-3;Q6XQN6;Q6XQN6-2 Q6XQN6-3 NAPRT Nicotinate phosphoribosyltransferase 1 0 LQALVNSLCAGQS(1)P 85.45 0.014127 5731700 1186.4 657.38 940.03 800.88 593.49 1219.1 1304.9 1514.6 983.88 901.35 TRUE FALSE FALSE 1092.495188 714.200998 974.8683387 797.5661708 586.4130194 966.2449179 1341.511982 1976.394568 875.9508255 932.6718454 1.171360745 0.765758076 1.045242594 0.855141253 0.628745279 1.035996661 1.438353681 2.11906747 0.939184376 1 9.865225757 -4.388853271 2.236322719 1.006520892 2.246020433 0.836420741 0.16151586 0.16129377 1.121607066 0.026135452 0.351382456 4.08E-05 4.388853271 1.239499541 up AVTGYK(ac)DPYSGK ddPTM_HeLa_Curcumin_4h_R1 1 AVTGYKDPYSGK 12 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 1 AVTGYK(1)DPYSGK 122.7 0.00088436 3282700 844.28 818.69 620.37 554.79 1342.6 2018.8 1343.2 908.4 1953.5 673.11 FALSE TRUE FALSE 777.4543471 889.4539156 643.3614579 552.494426 1326.590372 1600.078123 1380.886577 1185.366978 1739.205937 696.5005224 1.116229381 1.277032661 0.923705636 0.793243376 1.904650936 2.29731073 1.982606664 1.701889575 2.497063364 1 9.443980625 -5.70704358 7.064403885 1.04769274 2.003214089 0.269884538 0.492449972 0.055174676 5.751959635 0.026209781 0.052414743 1.96E-06 5.70704358 0.955521349 AVTIANS(ph)PSKPSEK ddPTM_HeLa_Curcumin_4h_R1 1 AVTIANSPSKPSEK 14 1 Q8NEF9 Q8NEF9 SRFBP1 Serum response factor-binding protein 1 1 0 AVT(0.001)IANS(0.991)PS(0.008)KPS(0.001)EK 80.638 0.0080949 320120000 5993.9 5846.7 6606.9 6103 6558.1 7864.5 6946.5 4705.7 5482.5 4999.7 TRUE FALSE FALSE 5519.47649 6352.062696 6851.757526 6077.747403 6479.898941 6233.314049 7141.400094 6140.446268 4881.083467 5173.439203 1.066887282 1.227822044 1.324410563 1.174798266 1.252532153 1.204868523 1.380397027 1.186917644 0.943489094 1 12.33690796 -7.306307524 2.673411527 1.027300942 1.256112924 0.75194028 0.064984949 0.094041713 1.283956043 0.010297823 0.011992442 4.94E-08 7.306307524 0.228811983 AVTIANSPS(ph)KPSEKDSVVSLESQK ddPTM_HeLa_Curcumin_4h_R1 2 AVTIANSPSKPSEKDSVVSLESQK 24 2 Q8NEF9 Q8NEF9 SRFBP1 Serum response factor-binding protein 1 1 0 AVTIANS(0.017)PS(0.644)KPS(0.304)EKDS(0.032)VVS(0.002)LESQK;AVTIANS(0.007)PS(0.988)KPS(0.005)EKDSVVSLESQK ; 112.64 1.13E-06 407700000 4479.5 3602.9 3549.3 4255.8 3731.1 5093.2 4664.7 2836.2 5498.4 4249.7 TRUE FALSE FALSE 4124.942848 3914.318622 3680.84018 4238.190627 3686.609069 4036.812908 4795.578928 3700.944324 4895.239276 4397.376759 0.938046266 0.890148567 0.83705363 0.963799751 0.838365524 0.918004785 1.090554481 0.84162548 1.113218072 1 12.10242743 -8.435173504 0.942995163 0.992150595 0.916623339 0.26166424 0.081661999 0.669087824 1.229516516 0.025074907 0.014685061 3.67E-09 8.435173504 -0.075527256 AVTIFIR ddPTM_HeLa_Curcumin_4h_R1 2 AVTIFIR 7 0 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 0 ; ; 114.02 0.011255 8932500 3633.3 1924.9 3027.8 2422.6 2908.2 3949 2954.9 3006.1 2373.29 2763.8 FALSE FALSE TRUE 3345.720471 2091.279779 3140.012932 2412.575923 2873.521614 3129.932886 3037.806541 3922.646052 2112.946025 2859.841844 1.169897027 0.731257144 1.097967336 0.843604666 1.004783401 1.09444265 1.06222886 1.371630414 0.738833173 1 11.48171965 -4.107752665 2.16800354 1.036267815 1.570452012 0.301669172 0.156998275 1.046851322 3.757021994 0.01875759 1.249716879 7.80E-05 4.107752665 0.534184198 AVTK(ac)AQK ddPTM_HeLa_Curcumin_4h_R1 2 AVTKAQK 7 1 P58876;P62807;P57053;O60814;Q16778;P06899;Q8N257;Q93079;U3KQK0;Q99877;Q99880 P58876;P62807;Q16778;Q8N257;Q93079;U3KQK0;Q99880 HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BL Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-L 0 1 ; AVTK(1)AQK;AVTK(1)AQK 121.62 0.0092029 53588000 16678.5 30334 9744.2 9836.4 7097.5 8008.2 10157.9 3693 5495 8136.2 FALSE TRUE FALSE 15358.37913 32955.93579 10105.32862 9795.699583 7012.866948 6347.209049 10442.90334 4818.9787 4892.212248 8418.932344 1.824266843 3.914502985 1.200309993 1.163532284 0.832987683 0.7539209 1.240407086 0.572397841 0.581096515 1 13.03942157 -6.340576745 4.027289135 1.623669792 0.913087154 0.184355902 0.846942957 0.376322752 11.57693139 0.134423728 0.210677861 4.56E-07 6.340576745 -0.710582638 AVTK(ac)AQK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AVTKAQKK 8 2 P58876;P62807;P57053;O60814;Q16778;P06899;Q8N257;Q93079;U3KQK0;Q99877;Q99880 P58876;P62807;Q16778;Q8N257;Q93079;U3KQK0;Q99880 HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BL Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-L 0 2 ; AVTK(1)AQK(1)K;AVTK(1)AQK(1)K 120.12 0.00801 107432000 15095.5 4884.4 10874.4 7042.6 10704.5 11238.9 9361.1 4963.4 8193.8 9750.7 FALSE TRUE FALSE 13900.67525 5306.585772 11277.41483 7013.459587 10576.85583 8907.825451 9623.747272 6476.717811 7294.96064 10089.5361 1.377731851 0.525949431 1.117733731 0.695122107 1.048299518 0.882877603 0.953834465 0.641924242 0.723022403 1 13.30057222 -7.276667085 24.98362426 1.178373368 0.857503473 0.025059862 0.239942097 650.9257844 1067951.471 0.03490063 0.039989291 5.29E-08 7.276667085 -0.320869895 AVTK(ac)VQK ddPTM_HeLa_Curcumin_4h_R1 2 AVTKVQK 7 1 Q5QNW6;Q5QNW6-2 Q5QNW6 HIST2H2BF Histone H2B type 2-F 0 1 ; AVTK(1)VQK;AVTK(1)VQK 119.17 0.0094489 494710000 24049 18595.7 22893 19750.8 22222 23021 21396.1 12612.3 18251.6 18653.1 FALSE TRUE FALSE 22145.49627 20203.02945 23741.43472 19669.07642 21957.01716 18246.1851 21996.41698 16457.73221 16249.44514 19301.29384 1.147358123 1.04671892 1.230043691 1.019054815 1.137593021 0.945334818 1.139634325 0.852675077 0.841883725 1 14.23640994 -4.251073759 24.32608989 1.076438837 0.852674894 0.221512031 0.108894888 793.6278232 1862435.597 0.011220345 0.205107071 5.61E-05 4.251073759 -0.223763944 AVTK(ac)YTSSK ddPTM_HeLa_Curcumin_4h_R1 2 AVTKYTSSK 9 1 P33778;P58876;P62807;Q16778;Q5QNW6;Q5QNW6-2;Q8N257;Q93079;U3KQK0;Q99877;Q99879;Q99880 P33778;P58876;P62807;Q16778;Q5QNW6;Q8N257;Q93079;U3KQK0;Q99879;Q99880 HIST1H2BB;HIST1H2BD;HIST1H2BC;HIST2H2BE;HIST2H2BF;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BM;HIST1H2BL Histone H2B type 1-B;Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type 2-E;Histone H2B type 2-F;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-M;Histone H2B type 1-L 0 1 ; AVTK(1)YTSSK;AVTK(1)YTSSK 157.24 4.31E-08 22545000 9255.1 6003.2 7412.6 6515.6 7665.9 9487.3 8124.9 7332.6 7754.9 7428.4 FALSE TRUE FALSE 8522.549069 6522.089858 7687.317477 6488.640174 7574.489149 7519.527036 8352.862827 9568.275985 6904.206872 7686.536347 1.108763256 0.848508296 1.000101623 0.844156572 0.985422927 0.978272488 1.086687482 1.244809828 0.898220806 1 12.90811793 -4.350180601 2.732650362 1.010969675 1.267100706 0.426445598 0.088822677 0.305423105 3.381260882 0.013207746 0.158272485 4.46E-05 4.350180601 0.256131031 NEGSVPTMMT(ph)RK ddPTM_HeLa_Curcumin_4h_R1 1 NEGSVPTMMTRK 12 1 Q9Y6X0 Q9Y6X0 SETBP1 SET-binding protein 1 0 NEGS(0.121)VPT(0.334)MMT(0.544)RK 57.53 0.0086323 0 1829.4 1144.9 1413.8 1666.5 1506.4 1486.2 805.12 487.95 1569.4 1379.3 TRUE FALSE FALSE 1684.60106 1243.860054 1466.196672 1659.604465 1488.437164 1177.945367 827.7095003 636.7237088 1397.240746 1427.230572 1.180328597 0.871520046 1.027301895 1.162814542 1.042884866 0.825336417 0.579940982 0.446125329 0.978987399 1 10.47900271 -4.868303204 1.725406232 1.071236706 0.446309758 0.848831764 0.088149089 0.113351607 0.609694163 0.014227345 0.079181288 1.35E-05 4.868303204 -0.624926948 down AVTTPGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AVTTPGKK 8 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 ; AVTTPGK(1)K;AVTTPGK(1)K 136.8 0.0003385 536230000 22169.8 18097.6 19439.3 17975.1 17251.6 23122 22431.3 19549.7 21074.2 16056.1 FALSE TRUE FALSE 20415.03694 19661.8759 20159.73756 17900.7238 17045.88594 18326.23656 23060.66191 25510.31353 18762.41299 16614.04828 1.228781607 1.183448824 1.21341513 1.077445033 1.02599232 1.103056657 1.388021843 1.535466438 1.129310128 1 14.02011603 -4.631355119 3.280233097 1.114415578 1.513166198 0.789563776 0.072174618 0.104485904 2.114656234 0.013936869 0.067757682 2.34E-05 4.631355119 0.39875062 AVTTVTQSTPVPGPSVPPPEELQVS(ph)PGPR ddPTM_HeLa_Curcumin_4h_R1 2 AVTTVTQSTPVPGPSVPPPEELQVSPGPR 29 0 P51610-2;P51610;H7C1C4 P51610-2 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 0 AVTTVTQSTPVPGPSVPPPEELQVS(1)PGPR;AVTTVTQSTPVPGPSVPPPEELQVS(1)PGPR ; 168.92 2.54E-16 128574000 4624 3571.4 3486.3 3994.8 4261.2 4944.4 3553.8 3719.3 4684.9 3737.4 TRUE FALSE FALSE 4258.005521 3880.095902 3615.505345 3978.270576 4210.387973 3918.875705 3653.510063 4853.297448 4170.978191 3867.274372 1.10103528 1.003315392 0.934897552 1.028701404 1.088722332 1.013343075 0.944724814 1.254965896 1.078531749 1 11.91710141 -4.246741444 24.49872676 1.032145476 1.254966104 0.620135671 0.054247458 1177.712284 1962985.761 0.008254784 0.240759954 5.67E-05 4.246741444 0.222820628 AVVGVVAGGGR ddPTM_HeLa_Curcumin_4h_R1 2 AVVGVVAGGGR 11 0 E9PKZ0;P62917;E9PKU4;E9PP36 E9PKZ0 RPL8 60S ribosomal protein L8 0 0 ; ; 153.73 2.61E-07 21268000 6079.4 4824.1 5930.5 5883.5 5465.7 6214.3 5652 4683.8 6143.3 5600 FALSE FALSE TRUE 5598.209075 5241.073708 6150.289547 5859.155636 5400.525097 4925.38413 5810.579908 6111.869058 5469.39536 5794.599583 0.966108011 0.904475561 1.06138301 1.011140727 0.931992801 0.849995597 1.002757796 1.054752614 0.943878051 1 12.50049326 -5.758072637 24.99485603 0.98514168 0.955089277 0.022550719 0.062501721 239.6945039 1779477.766 0.00906037 0.017550216 1.75E-06 5.758072637 -0.030052403 AVVIVDDR ddPTM_HeLa_Curcumin_4h_R1 2 AVVIVDDR 8 0 Q15233;Q15233-2;C9IZL7;H7C367;P23246;P23246-2 Q15233;P23246 NONO;SFPQ "Non-POU domain-containing octamer-binding protein;Splicing factor, proline- and glutamine-rich" 0 0 ; ; 130.04 0.0016588 23035000 11961.8 9391.1 10067.7 10094.5 10554.4 12546.7 10900.7 9937.3 11920.6 11047.8 FALSE FALSE TRUE 11015.01091 10202.82484 10440.81782 10052.73163 10428.54567 9944.37299 11206.5443 12967.13702 10612.94 11431.71023 0.963548821 0.892502052 0.91332072 0.879372503 0.912247202 0.869893725 0.980303391 1.134312956 0.928377276 1 13.48075363 -7.87177098 1.62016055 0.989375065 0.935195933 0 0.074968806 0.612010996 3.334178787 0.016097768 0.014853685 1.34E-08 7.87177098 -0.054179132 AVVPSK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 AVVPSKR 7 1 P07910;P07910-2;G3V2Q1;G3V4C1;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7;G3V576;G3V555;G3V575 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 0 1 ; AVVPSK(1)R;AVVPSK(1)R 102.71 0.0063905 65916000 4472.6 3566.6 3482.3 3213.1 3676.9 6802.3 4675.7 4302.8 4618.6 3646.1 FALSE TRUE FALSE 4118.588991 3874.881012 3611.357101 3199.805044 3633.055369 5391.426302 4806.887558 5614.703912 4111.951135 3772.801704 1.091652653 1.027056632 0.957208299 0.848124364 0.962959534 1.429024562 1.274089638 1.488205412 1.089893257 1 11.88142056 -5.260540957 24.99999864 1.016695835 1.384804865 0.824220526 0.084326816 27.2584196 758493.1239 0.012794153 0.030655248 5.49E-06 5.260540957 0.36810903 AVVQS(ph)PQVTEVL ddPTM_HeLa_Curcumin_4h_R1 1 AVVQSPQVTEVL 12 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 AVVQS(1)PQVTEVL 105.65 0.0068732 6889200 2701.3 2111.5 2341.8 2324.7 2567.9 3734.4 4013.9 2046.2 2528.9 1915.4 TRUE FALSE FALSE 2487.489255 2294.008651 2428.589168 2315.081007 2537.27947 2959.843345 4126.519231 2670.07696 2251.485997 1981.960007 1.255065312 1.15744447 1.225347211 1.16807655 1.280187017 1.493392063 2.082039605 1.34719013 1.135989621 1 10.95271214 -5.229531497 2.420673318 1.140541094 1.723290031 0.592119554 0.181958299 0.136546987 1.553302091 0.025892399 0.076661541 5.89E-06 5.229531497 0.582748937 AVVS(ph)PPKFVFGSESVK ddPTM_HeLa_Curcumin_4h_R1 1 AVVSPPKFVFGSESVK 16 1 P49792;J3KNE0;A6NKT7;F8VYC4;P0DJD0;P0DJD1;A0A1W2PNU4;A0A286YES2;Q7Z3J3 P49792 RANBP2;RGPD3;RGPD1;RGPD2;RGPD4 E3 SUMO-protein ligase RanBP2;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4 1 0 AVVS(0.713)PPKFVFGS(0.195)ES(0.093)VK 58.159 0.019603 539720000 3424.5 2808.2 2827.8 2807.7 2995.2 2963.2 1912.2 1391.4 3433.7 2972.2 TRUE FALSE FALSE 3153.447211 3050.928295 2932.600756 2796.082481 2959.484196 2348.598918 1965.851186 1815.631455 3057.031701 3075.483729 1.02534999 0.992015749 0.953541301 0.909152097 0.962282508 0.763651876 0.639200646 0.590356385 0.994000284 1 11.58659763 -4.90352827 0.847176772 1.00811536 0.499178541 0.956152859 0.031716997 0.147953625 0.133103514 0.005258879 0.05697636 1.25E-05 4.90352827 -0.50893682 AVVSK(ac)ATTKPPPAKK ddPTM_HeLa_Curcumin_4h_R1 1 AVVSKATTKPPPAKK 15 3 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 1 AVVSK(0.977)ATTK(0.023)PPPAKK 67.234 0.010866 2377600 1976.5 1890 1874.3 1734.9 1579.5 2703.5 1934.1 1120.5 1972.8 1630.4 FALSE TRUE FALSE 1820.057939 2053.363178 1943.763207 1727.721443 1560.665494 2142.763625 1988.365641 1462.135292 1756.388776 1687.056279 1.078836529 1.217127848 1.152162635 1.024104214 0.925082058 1.270119825 1.178600658 0.866678433 1.04109673 1 10.72029239 -8.64371768 1.052787898 1.008963551 1.094647057 0.045053132 0.119767745 0.92363226 2.063851663 0.043244055 0.023112056 2.27E-09 8.64371768 0.085683506 AVVVS(ph)PKEENK ddPTM_HeLa_Curcumin_4h_R1 1 AVVVSPKEENK 11 1 G3V5E1;O75909-1;O75909 G3V5E1 CCNK Cyclin-K 1 0 AVVVS(1)PKEENK 65.043 0.020273 274160000 13870 11637 13433 13408 12948 14013 12328 9370.2 13005 10907 TRUE FALSE FALSE 12772.17486 12642.85043 13930.8388 13352.52125 12793.60356 11106.54584 12673.8905 12227.13084 11578.38404 11286.01744 1.131681298 1.120222478 1.234344965 1.183103014 1.133579992 0.984097881 1.122972791 1.083387556 1.025905205 1 13.46224886 -9.11127683 0.880989997 1.000195058 1.124939246 0.340630256 0.061405142 0.542927669 0.76362814 0.04297615 0.012683568 7.74E-10 9.11127683 0.124744188 AVYDEQGTVDEDSPVLTQDRDWEAYWR ddPTM_HeLa_Curcumin_4h_R1 2 AVYDEQGTVDEDSPVLTQDRDWEAYWR 27 1 Q8WXX5 Q8WXX5 DNAJC9 DnaJ homolog subfamily C member 9 0 0 ; ; 129.26 1.80E-08 42506000 1985.86 1666 1703.14 1488.25 1529.28 2588.63 1839.28 1899.81 2044.88 1671.37 FALSE FALSE TRUE 1828.677086 1810.001616 1766.259867 1482.092016 1511.044335 2051.718958 1890.885247 2479.053323 1820.56178 1729.449983 1.057374948 1.046576446 1.021284156 0.856973044 0.873713811 1.186341888 1.093344858 1.43343453 1.052682528 1 10.75609758 -3.889445574 1.235399098 1.011087436 2.000886015 0.693061085 0.085423869 1.43818809 0.994668858 0.01288435 2.261926661 0.00012899 3.889445574 0.989798579 AWEDYYK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AWEDYYKK 8 1 Q96I24 Q96I24 FUBP3 Far upstream element-binding protein 3 0 1 ; AWEDYYK(1)K;AWEDYYK(1)K 86.953 0.010083 13885800 5362.6 4985.1 3706.3 4590.1 6053.4 12585.4 5713.7 5031 6545.9 4431.7 FALSE TRUE FALSE 4938.144551 5415.989831 3843.658738 4571.107382 5981.217159 9975.046173 5874.011044 6564.92874 5827.831147 4585.701245 1.076857014 1.181060331 0.838183417 0.996817529 1.304318977 2.1752499 1.280940631 1.431608469 1.270870219 1 12.16292665 -5.517213729 9.000105722 1.034775942 1.618739695 0.526902055 0.240641615 0.066284491 60.93740914 0.031191709 0.065433339 3.04E-06 5.517213729 0.583963753 AWGPGLEGGVVGK ddPTM_HeLa_Curcumin_4h_R1 2 AWGPGLEGGVVGK 13 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 190.86 3.24E-13 12570900 5542.5 3381.6 4670.7 4518.9 5315.8 6349.8 5053.7 4828.2 4288.2 4329.6 FALSE FALSE TRUE 5103.805277 3673.890436 4843.800251 4500.201989 5252.412557 5032.779903 5195.493221 6300.295954 3817.795189 4480.053278 1.139228701 0.820055077 1.081192555 1.004497427 1.172399575 1.123375012 1.159694517 1.406299337 0.852176292 1 12.12930017 -1 0.679159586 1.0472911 39.54363531 0.549764571 0.107810864 132.3116518 0.710346724 0.015617526 7718.212783 0.1 1 38.49634421 AWLDEDSNLS(ph)PSPLR ddPTM_HeLa_Curcumin_4h_R1 1 AWLDEDSNLSPSPLR 15 0 Q9C086;B8ZZ93;B8ZZH7;F8WCL7;J3KQ70 Q9C086 INO80B;INO80B-WBP1 INO80 complex subunit B 1 0 AWLDEDS(0.021)NLS(0.928)PS(0.051)PLR 81.327 0.014746 4667900 604.12 439.21 619.3 605.43 492.6 746.08 587.25 846.17 646.72 642.76 TRUE FALSE FALSE 556.3032645 477.1733553 642.2518028 602.9248911 486.7260667 591.3345979 603.7266545 1104.163338 575.776434 665.0958622 0.836425689 0.717450495 0.965652982 0.906523293 0.731813404 0.889096793 0.907728778 1.660156679 0.86570443 1 9.377418485 -4.261389961 6.556523336 0.893175981 1.674983259 0.877768954 0.088177005 0.033650706 8.908904851 0.013951039 0.116139652 5.48E-05 4.261389961 0.781807278 APS(ph)PTSSAGEEGTK ddPTM_HeLa_Curcumin_4h_R1 1 APSPTSSAGEEGTK 14 0 O94964-2;H0YDM2;O94964;O94964-3 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 1 0 APS(0.778)PT(0.185)S(0.034)S(0.003)AGEEGTK 87.363 0.012382 10746000 4542.1 4172.5 4022.9 4326.9 4077.5 4097.2 2567.6 1553.9 4514.8 4096.6 TRUE FALSE FALSE 4182.587992 4533.152308 4171.992213 4308.996434 4028.878476 3247.394535 2639.639946 2027.676957 4019.537735 4238.956545 0.986702257 1.069402873 0.984202638 1.016522908 0.950441089 0.766083469 0.622709839 0.478343417 0.948237542 1 12.04949346 -4.861612706 1.307438303 1.002050384 0.460598163 0.969710132 0.032149157 0.057867458 0.15621879 0.004171779 0.03113578 1.38E-05 4.861612706 -0.54145222 down AWLDEDSNLSPS(ph)PLR ddPTM_HeLa_Curcumin_4h_R1 1 AWLDEDSNLSPSPLR 15 0 Q9C086;B8ZZ93;B8ZZH7;F8WCL7;J3KQ70 Q9C086 INO80B;INO80B-WBP1 INO80 complex subunit B 1 0 AWLDEDSNLS(0.001)PS(0.999)PLR 150.01 0.00044387 4412400 827.94 984.3 1221.5 868.64 1093 870.03 883.53 847.21 999.08 1094 TRUE FALSE FALSE 762.4076754 1069.378506 1266.769865 865.0457978 1079.966689 689.5759707 908.3194739 1105.520429 889.4834236 1132.016419 0.673495245 0.944666958 1.11903842 0.76416365 0.95402034 0.609157217 0.802390724 0.976593988 0.785751345 1 10.14467917 AWNDIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AWNDIKK 7 1 P36578;H3BM89;H3BTP7 P36578 RPL4 60S ribosomal protein L4 0 1 ; AWNDIK(1)K;AWNDIK(1)K 96.711 0.0082463 7904700 2612.09 3437.75 2933.43 2787.23 5838.7 6896.9 4973.2 5326.7 7201.2 2938.21 FALSE TRUE FALSE 2405.34032 3734.893792 3042.145496 2775.697181 5769.077316 5466.405196 5112.734607 6950.786309 6411.246377 3040.312579 0.791149021 1.228457172 1.000602871 0.91296441 1.897527694 1.797974733 1.681647684 2.286207792 2.108745798 1 11.57000394 -5.760874294 24.98861731 0.935329456 1.890692734 0.365181226 0.412472576 3.798291046 167949.469 0.026770581 0.051066112 1.73E-06 5.760874294 0.955363278 AWSS(ph)QDEVSTNVR ddPTM_HeLa_Curcumin_4h_R1 1 AWSSQDEVSTNVR 13 0 A1L390-3;A1L390;A0A0U1RR71 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 0 AWS(0.013)S(0.986)QDEVST(0.001)NVR 120.53 0.0024436 0 1710.4 1370.1 1527.9 1830.9 1713 2263.2 2207.1 1396 1656.2 1572.5 TRUE FALSE FALSE 1575.020035 1488.525339 1584.525318 1823.324221 1692.573594 1793.786808 2269.025286 1821.633974 1474.519004 1627.144258 0.967965826 0.914808464 0.973807522 1.120567038 1.040211146 1.102414122 1.394483172 1.119528256 0.906200539 1 10.66812645 -5.313538465 1.111822373 0.980749424 1.258965019 0.605280887 0.085489458 0.26616286 0.577758654 0.012067895 0.055212597 4.86E-06 5.313538465 0.278215594 AWVWNTHADFADECPKPELLAIR ddPTM_HeLa_Curcumin_4h_R1 2 AWVWNTHADFADECPKPELLAIR 23 1 P43487-2;P43487;F6WQW2;C9JXG8;C9JJ34;C9JGV6 P43487-2 RANBP1 Ran-specific GTPase-activating protein 0 0 ; ; 104.89 1.15E-05 22480000 1465.37 1307.81 1637.46 1181.32 1200.1 8447.7 4119.7 3765.2 2101 1724.69 FALSE FALSE TRUE 1349.384418 1420.851269 1698.145708 1176.432011 1185.789591 6695.551795 4235.287694 4913.192147 1870.525556 1784.622849 0.756117417 0.796163329 0.951543184 0.659204835 0.664448285 3.751802123 2.373211626 2.753070291 1.048134936 1 10.8014035 -5.273129741 24.99943568 0.850598112 2.900746376 0.88882734 0.343380619 148.6223342 317823.7091 0.045036136 0.10147225 5.33E-06 5.273129741 2.050148264 AY(ph)EKAEKS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 AYEKAEKSK 9 2 A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YHT2;Q7Z4S6-3;H0YI78 A0A1B0GV47 KIF21A Kinesin-like protein KIF21A 2 0 AY(1)EKAEKS(1)K 71.03 0.0087946 0 1059.8 905.08 920.09 1036.4 880.01 1526.5 1152.4 1012.4 967.93 884.72 TRUE FALSE FALSE 975.9157117 983.3110822 954.1893448 1032.111651 869.5164555 1209.886693 1184.733242 1321.076099 861.7505006 915.4639541 1.066034012 1.074112288 1.042301382 1.127419214 0.949809604 1.321610411 1.294134233 1.443067303 0.941326523 1 9.838359272 -5.19963672 6.383112832 1.038813636 1.35071898 0.84248648 0.064164947 0.059383934 4.894403759 0.007806407 0.020093444 6.31E-06 5.19963672 0.311905345 AYEEAQK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 AYEEAQKR 8 1 A2AB15;A0A140T947;O60231 A2AB15 DHX16 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 0 1 ; AYEEAQK(1)R;AYEEAQK(1)R 114.89 0.001275 5671700 2279.75 1941.75 2141.73 2103.3 2015.51 2771.4 2089.77 2048.85 2495 2123.86 FALSE TRUE FALSE 2099.305382 2109.586218 2221.104398 2094.597102 1991.47636 2196.5804 2148.403322 2673.534933 2221.304742 2197.663977 0.955244025 0.959922099 1.010666062 0.953101622 0.906178734 0.999506941 0.977584992 1.216534903 1.010757225 1 11.1017551 -4.260935426 6.620347332 0.97392491 1.221086123 0.845553864 0.030999346 0.032130865 8.896575926 0.004219579 0.03526554 5.48E-05 4.260935426 0.247161213 AYFETEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 AYFETEKK 8 1 H3BR35;P15170;P15170-2;P15170-3;H3BSV8 H3BR35 GSPT1 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A 0 1 ; AYFETEK(1)K;AYFETEK(1)K 120.07 0.00091587 6855500 2513.9 2767.4 2584.4 2135.29 4024.7 4272.1 3723.5 3851.7 4787.3 2360.9 FALSE TRUE FALSE 2314.922162 3006.601725 2680.180137 2126.454736 3976.708081 3386.018304 3827.971389 5026.065599 4262.145167 2442.941099 0.947596388 1.230730338 1.097112058 0.870448631 1.627836251 1.386041728 1.566951978 2.057383046 1.744677826 1 11.25440336 -1.000017604 0.357168257 0.9620423 14.39861579 0.365515662 0.295282498 16.00036513 0.199154558 0.044082148 147.6693715 0.099995947 1.000017604 13.43657349 AYFHLLNQIAPK ddPTM_HeLa_Curcumin_4h_R1 1 AYFHLLNQIAPK 12 0 P13797;A0A0A0MSQ0;P13797-3;P13797-2;H7C4N2;Q14651;C9JAM8 P13797 PLS3;PLS1 Plastin-3;Plastin-1 0 0 91.855 0.0051471 2204500 3300.3 2166.5 3222.9 2502.4 2927.5 4850.4 3181.7 3701.7 2833.6 2804.2 FALSE FALSE TRUE 3039.077773 2353.762606 3342.343509 2492.045732 2892.591475 3844.372365 3270.969939 4830.331289 2522.761169 2901.645741 1.047363477 0.811181935 1.151878557 0.858838726 0.99687961 1.32489377 1.12728094 1.664686774 0.869424249 1 11.50265568 -1.000000008 0.744591803 1.004968532 110.7821478 0.710052446 0.130665893 129.4180951 0.535901912 0.018383262 23837.95065 0.099999998 1.000000008 109.7771792 AYFLY(ph)MY(ph)S(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 AYFLYMYSR 9 0 Q9UJX2;Q9UJX2-2 Q9UJX2 CDC23 Cell division cycle protein 23 homolog 3 0 AY(0.011)FLY(0.995)MY(0.995)S(1)R 55.084 0.020099 1495200 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 AYGELPEHAK ddPTM_HeLa_Curcumin_4h_R1 1 AYGELPEHAK 10 0 X6RAC9;P47813;O14602;A6NJH9 X6RAC9 EIF1AX;EIF1AY "Eukaryotic translation initiation factor 1A, X-chromosomal;Eukaryotic translation initiation factor 1A, Y-chromosomal" 0 0 95.483 0.012432 9152100 7846.7 6357.3 6170.5 6988.9 7271.2 8595 6251.7 5909.8 7846.7 6651 FALSE FALSE TRUE 7225.625415 6906.796684 6399.184158 6959.981784 7184.495689 6812.300114 6427.105876 7711.670815 6985.936641 6882.121755 1.049912465 1.003585367 0.929827223 1.011313376 1.04393615 0.989854635 0.933884361 1.120536818 1.015084721 1 12.7486377 -7.030929497 24.31587069 1.023737101 1.000019119 0.016217977 0.052257316 1312.526082 1031868.45 0.008422957 0.010321787 9.31E-08 7.030929497 -0.023717982 AYGPGIEPTGNMVK ddPTM_HeLa_Curcumin_4h_R1 1 AYGPGIEPTGNMVK 14 0 P21333-2;P21333;F8WE98;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 231.05 5.04E-37 5657400 2686.5 1897.5 2469 2211.6 2846 3107.8 2143 2015.1 1957.2 1755.9 FALSE FALSE TRUE 2473.86069 2061.511445 2560.503312 2202.448985 2812.063309 2463.207248 2203.126812 2629.494714 1742.500057 1816.917394 1.361570261 1.134620347 1.409256865 1.212189939 1.547711149 1.35570679 1.212563003 1.447228543 0.959041981 1 10.82727711 -10.26411959 0.36262862 0.702214472 1.358818438 0.613708956 0.11424179 3.00746478 0.295492581 0.853970577 0.038936972 5.44E-11 10.26411959 0.656603966 AYGPGLEK ddPTM_HeLa_Curcumin_4h_R1 1 AYGPGLEK 8 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 101.64 0.011915 5875100 4849.9 3688.1 4544.3 4035 4186.3 5655.6 4401.1 4356.5 4409 4241.8 FALSE FALSE TRUE 4466.025297 4006.88293 4712.715756 4018.304239 4136.381107 4482.564808 4524.583021 5684.776795 3925.343731 4389.202234 1.017502739 0.912895491 1.073706679 0.915497629 0.942399299 1.021270967 1.030844053 1.29517313 0.894318266 1 12.09974303 -4.22116908 2.748468884 0.995827691 1.37002541 0.7243074 0.058092828 0.179692265 1.656966892 0.006452678 0.158104251 6.01E-05 4.22116908 0.374197719 TPTS(ph)PLSPSSQK ddPTM_HeLa_Curcumin_4h_R1 1 TPTSPLSPSSQK 12 0 Q5VT06 Q5VT06 CEP350 Centrosome-associated protein 350 1 0 T(0.003)PT(0.004)S(0.983)PLS(0.009)PSSQK 136.27 0.0016632 5667000 2778.8 1887.1 2447.1 2063.4 2230.5 2360.6 972.13 725.39 2474.1 1918.9 TRUE FALSE FALSE 2558.855048 2050.212515 2537.791679 2054.862198 2203.902744 1870.984951 999.4053514 946.5580717 2202.69742 1985.581632 1.28871813 1.032550101 1.278109969 1.034891824 1.109953229 0.942285585 0.503331284 0.476715768 1.109346191 1 10.95534596 -4.857911379 2.3090942 1.13336984 0.45242372 0.877758495 0.092888727 0.089586229 0.927476767 0.016952913 0.075457255 1.39E-05 4.857911379 -0.68094612 down AYLGYQAVPSGS(ph)SGSLSTSSSSSPPGT(ph)PSPADAK ddPTM_HeLa_Curcumin_4h_R1 1 AYLGYQAVPSGSSGSLSTSSSSSPPGTPSPADAK 34 0 P17676-3;P17676-2;P17676 P17676-3 CEBPB CCAAT/enhancer-binding protein beta 2 0 AYLGYQAVPS(0.067)GS(0.217)S(0.217)GS(0.17)LS(0.072)T(0.042)S(0.058)S(0.101)S(0.078)S(0.078)S(0.078)PPGT(0.727)PS(0.097)PADAK 57.896 0.00083957 4714000 3331.1 2658.2 3221 2892.9 3020.3 4163.9 3744.4 2661.3 3688.5 2465 TRUE FALSE FALSE 3067.43992 2887.962963 3340.373093 2880.929946 2984.284895 3300.260203 3849.457786 3472.718119 3283.880778 2550.658567 1.202607029 1.132242081 1.309612011 1.129484747 1.170005635 1.293885527 1.50920152 1.36149862 1.287463881 1 11.31665408 -1 0.102662184 0.879909981 2.458015135 0.27929358 0.115454836 51.92683266 0.378418016 0.654262581 11.60882165 0.1 1 1.578105154 AYS(ph)GSDLPSSSSGGANGTAGGGGGAR ddPTM_HeLa_Curcumin_4h_R1 4 AYSGSDLPSSSSGGANGTAGGGGGAR 26 0 Q8NHG8 Q8NHG8 ZNRF2 E3 ubiquitin-protein ligase ZNRF2 1 0 AYS(0.992)GS(0.008)DLPSSSSGGANGTAGGGGGAR;AYS(0.986)GS(0.014)DLPSSSSGGANGTAGGGGGAR;AY(0.002)S(0.661)GS(0.337)DLPSSSSGGANGTAGGGGGAR;AYS(0.601)GS(0.399)DLPSSSSGGANGTAGGGGGAR ;;; 364.92 8.10E-212 124514000 7497.6 6353.4 6839.1 6792.1 6642.8 9061.6 5395.4 4157.57 8136.4 6839.7 TRUE FALSE FALSE 6904.157049 6902.559586 7092.563062 6763.99609 6563.588949 7182.122015 5546.780403 5425.193954 7243.857276 7077.379066 0.975524553 0.975298839 1.002145426 0.955720476 0.9274039 1.01479968 0.783733689 0.766554102 1.023522579 1 12.78899948 -4.754594189 24.99999856 0.982966351 0.775143766 0.904282671 0.027216573 28.73557889 104945.15 0.003405275 0.012192335 1.76E-05 4.754594189 -0.207822585 AYS(ph)NSIVR ddPTM_HeLa_Curcumin_4h_R1 2 AYSNSIVR 8 0 Q9H1Z4 Q9H1Z4 WDR13 WD repeat-containing protein 13 1 0 AYS(0.995)NS(0.005)IVR;AYS(0.999)NS(0.001)IVR ; 112.85 0.010464 69164000 3389.8 2216.88 2818.4 2835 2957.3 3023.5 2811.7 2051.19 3315.2 2670.3 TRUE FALSE FALSE 3121.493753 2408.497229 2922.852383 2823.269521 2922.036129 2396.392018 2890.588735 2676.588388 2951.530854 2763.092726 1.129710097 0.871667174 1.057819144 1.021778782 1.057523731 0.867286138 1.046142501 0.96869293 1.068198264 1 11.43206826 -7.290561285 24.99412009 1.061251983 0.989356939 0.211206487 0.07160678 961.965071 825612.1874 0.013074431 0.014952499 5.12E-08 7.290561285 -0.071895045 AYS(ph)SPSTTPEAR ddPTM_HeLa_Curcumin_4h_R1 1 AYSSPSTTPEAR 12 0 G3V2R1;Q9UPU9-2;Q9UPU9-3;Q9UPU9 G3V2R1 SAMD4A Protein Smaug homolog 1 1 0 AYS(0.628)S(0.369)PS(0.002)T(0.002)TPEAR 158.3 0.00026643 100830000 5648.4 5676.6 5418.3 5973.9 5213 5787.2 4199.9 3571 6549.4 5892.5 TRUE FALSE FALSE 5201.32318 6167.26001 5619.106964 5949.181585 5150.83838 4586.869485 4317.737891 4659.781461 5830.947206 6097.263936 0.853058558 1.011479915 0.921578436 0.975713311 0.844778647 0.752283243 0.708143511 0.764241389 0.956321928 1 12.57394628 -5.447096713 2.707928353 0.937711274 0.736325938 0.809187862 0.045730556 0.119493155 1.707325701 0.008852036 0.021678688 3.57E-06 5.447096713 -0.201385336 AYSDPSTGEPATYGELQQR ddPTM_HeLa_Curcumin_4h_R1 1 AYSDPSTGEPATYGELQQR 19 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 185.2 5.43E-08 2195800 0 145.29 0 0 75.878 0 0 0 169.75 0 FALSE FALSE TRUE 0 157.8482202 0 0 74.97320441 0 0 0 151.1288497 0 0 AYSSFGGGR ddPTM_HeLa_Curcumin_4h_R1 2 AYSSFGGGR 9 0 Q15056;Q15056-2 Q15056 EIF4H Eukaryotic translation initiation factor 4H 0 0 ; ; 110.31 0.0035205 5997800 1466.64 969.14 1261.45 1370.95 1226.87 1363.69 1027.8 1419.21 1454.28 1369.64 FALSE FALSE TRUE 1350.553896 1052.908143 1308.200447 1365.277372 1212.240377 1080.845322 1056.637302 1851.920596 1294.749122 1417.234888 0.952949936 0.74293129 0.92306537 0.963338811 0.855356008 0.762643745 0.745562582 1.306713948 0.913574125 1 10.46886317 -7.497715863 15.70422963 0.979249011 0.887310443 0.017497023 0.156589431 8.049122577 5024.930007 0.025474038 0.027710095 3.18E-08 7.497715863 -0.091938569 AYSSFGGGRGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 3 AYSSFGGGRGSR 12 1 Q15056;Q15056-2 Q15056 EIF4H Eukaryotic translation initiation factor 4H 1 0 AYSSFGGGRGS(1)R;AYSSFGGGRGS(1)R;AYSSFGGGRGS(1)R ;; 77.372 0.012036 47948000 9023 5897.2 7344 7080 6766.2 9935.1 7731.1 4347.9 7401.7 6509 TRUE FALSE FALSE 8308.820029 6406.927691 7616.1751 7050.704836 6685.517484 7874.448268 7948.013859 5673.554695 6589.752028 6735.187266 1.233643506 0.951261997 1.130803762 1.046846147 0.99262533 1.169150605 1.180073181 0.842375196 0.978406653 1 12.71750234 -7.249094279 24.95185186 1.110331659 1.056111844 0 0.118025165 2250.764694 4549230.218 0.020623481 0.025167737 5.64E-08 7.249094279 -0.054219815 SPSLSPS(ph)PPSPLEKTPLGER ddPTM_HeLa_Curcumin_4h_R1 1 SPSLSPSPPSPLEKTPLGER 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(0.001)PS(0.004)LS(0.105)PS(0.787)PPS(0.103)PLEKTPLGER 114.63 6.82E-05 117620000 1774.1 1139.9 1118.3 1286.8 1083.4 3665.6 3617.4 4815.1 2682.8 2086.3 TRUE FALSE FALSE 1633.678113 1238.427877 1159.745182 1281.475563 1070.481163 2905.31324 3718.894508 6283.201824 2388.503552 2158.79877 0.756753309 0.573665269 0.537217826 0.593605843 0.495868896 1.34580086 1.72266844 2.91050834 1.106403981 1 11.07601305 -4.383063014 1.398531753 0.790864855 3.461999787 0.901061098 0.223944826 0.232556383 0.472794485 0.035334492 0.813609542 4.14E-05 4.383063014 2.671134932 up AYT(ph)HQVVTR ddPTM_HeLa_Curcumin_4h_R1 1 AYTHQVVTR 9 0 D6REC6;D6R9G1;D6RAD4;P50613 D6REC6 CDK7 Cyclin-dependent kinase 7 1 0 AYT(1)HQVVTR 90.697 0.017657 47076000 5755.6 3605.8 6215.1 4159.8 6083.3 4558.6 4701.6 6026.9 4086.4 4063.9 TRUE FALSE FALSE 5300.038187 3917.469285 6445.437073 4142.58785 6010.760621 3613.094974 4833.514242 7864.474066 3638.132144 4205.120223 1.260377327 0.931595074 1.532759287 0.985129469 1.42939091 0.859213241 1.149435447 1.870213846 0.865167213 1 12.03793133 -4.262383323 7.208765059 1.134456327 1.879625479 0.510554581 0.221657897 0.057479201 25.20072475 0.026300869 0.209669009 5.47E-05 4.262383323 0.745169153 LEASYS(ph)DSPPGEEDLLVHVAEGSK ddPTM_HeLa_Curcumin_4h_R1 1 LEASYSDSPPGEEDLLVHVAEGSK 24 0 Q7Z3C6;C9JS65;C9JFV2;F2Z3I6;C9JX27;C9IYZ9;C9JKV7;C9JDK4;C9JXG2;Q7Z3C6-3 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 0 LEAS(0.373)Y(0.035)S(0.452)DS(0.14)PPGEEDLLVHVAEGSK 45.558 0.01917 12512000 3692.9 2687.8 3649.5 3787 2957.3 2578.1 1339.4 311.53 3371.5 3721.4 TRUE FALSE FALSE 3400.603068 2920.121455 3784.75368 3771.330397 2922.036129 2043.372999 1376.979959 406.5140629 3001.654885 3850.718373 0.883108745 0.758331608 0.98286951 0.979383593 0.758828833 0.53064722 0.357590409 0.10556837 0.779505171 1 11.9109119 -4.857102129 1.036933338 0.936835797 0.036516286 0.899686465 0.089145728 0.159166175 0.234569994 0.012994189 0.125217851 1.39E-05 4.857102129 -0.900319512 down AYTNFDAER ddPTM_HeLa_Curcumin_4h_R1 1 AYTNFDAER 9 0 H0YMW4;P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4;P07355-2 H0YMW4;P07355;P07355-2 ANXA2;ANXA2P2 Annexin;Annexin A2;Putative annexin A2-like protein 0 0 91.265 0.019459 4564400 1592.1 739.96 1005.4 1297.2 1673.5 1909.6 1419.9 1565.3 1359.9 1247.5 FALSE FALSE TRUE 1466.083605 803.9188452 1042.661008 1291.83253 1653.544605 1513.527434 1459.738573 2042.552764 1210.722372 1290.850532 1.135750088 0.622782286 0.807731788 1.000760737 1.280972943 1.172504017 1.130834699 1.582330962 0.937926074 1 10.33410625 -1 0.699538103 1.01632132 68.95414368 0.530053367 0.170883053 192.9055064 0.957258894 0.030744498 20526.30146 0.1 1 67.93782236 AYTNFDAERDALNIETAIK ddPTM_HeLa_Curcumin_4h_R1 1 AYTNFDAERDALNIETAIK 19 1 H0YMW4;P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4;P07355-2 H0YMW4;P07355;P07355-2 ANXA2;ANXA2P2 Annexin;Annexin A2;Putative annexin A2-like protein 0 0 82.121 0.0032907 0 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 AYTPSK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 AYTPSKR 7 1 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 0 1 AYTPSK(1)R 116.9 0.0033199 3494500 2559.5 1437.9 2547.6 1840.9 2385 2687.7 2019.9 1404.4 2189.5 1952.6 FALSE TRUE FALSE 2356.912874 1562.185669 2642.016297 1833.282844 2356.560433 2130.240723 2076.572958 1832.595095 1949.317328 2020.452705 1.16652712 0.773185962 1.307635804 0.907362414 1.166352683 1.054338326 1.027776079 0.907022021 0.964792357 1 10.98046287 -4.263061463 2.227237417 1.067380654 0.866050695 0.052817167 0.143074269 1.078316801 6.070994872 0.018120318 0.425830894 5.46E-05 4.263061463 -0.20132996 AYTTGSPGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 AYTTGSPGSR 10 0 H3BMG9;H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4 H3BMG9 FAM65A Protein FAM65A 1 0 AYTT(0.029)GS(0.465)PGS(0.506)R 101.72 0.011434 36708000 1866 1938.1 1917.1 1903.9 2253.2 2987.6 2172.6 932.68 2187.4 1908.1 TRUE FALSE FALSE 1718.304131 2105.620728 1988.149412 1896.022166 2226.332062 2367.938083 2233.557309 1217.049838 1947.447693 1974.406333 0.870289009 1.066457645 1.006960614 0.960299881 1.127595685 1.199316495 1.131255138 0.616413054 0.986345951 1 10.94720321 -7.248523537 23.99613015 0.938747586 1.028858589 0.027148387 0.1538502 989.2211737 1837858.115 0.02523456 0.030787879 5.64E-08 7.248523537 0.090111003 CAAPRPPSS(ph)SPEQR ddPTM_HeLa_Curcumin_4h_R1 1 CAAPRPPSSSPEQR 14 1 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 1 0 CAAPRPPS(0.147)S(0.743)S(0.11)PEQR 64.52 0.018257 25505000 536.16 981.7 677.75 822.68 812.28 807.44 563.32 604.03 813.56 610.65 TRUE FALSE FALSE 493.7223702 1066.553774 702.8680112 819.2759681 802.5940915 639.9678423 579.1252431 788.1959664 724.3145034 631.870042 0.781366954 1.687932174 1.112361664 1.296589352 1.270188548 1.01281561 0.916525875 1.247402019 1.146302966 1 9.303484057 CAGNEDIITLR ddPTM_HeLa_Curcumin_4h_R1 1 CAGNEDIITLR 11 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 0 120.63 0.0020208 2165800 1338.8 1468 1157.6 1289.6 1313.7 1543.8 1325.4 1238 1639.1 1291.8 FALSE FALSE TRUE 1232.832567 1594.887379 1200.501674 1284.263977 1298.034986 1223.598478 1362.587157 1615.460501 1459.294831 1336.689954 0.922302561 1.193161791 0.898115282 0.960779254 0.971081575 0.915394385 1.019374129 1.208552886 1.091722749 1 10.38444915 -4.293131872 3.405114996 0.972002921 1.231076024 0.327442835 0.086901826 0.185904953 3.645639217 0.010441649 0.118649887 5.09E-05 4.293131872 0.259073103 CALQNS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 CALQNSPR 8 0 X6R5G7;E9PRG2;E9PKY2;A0A0C4DFM7;Q5TAX3-2;Q5TAX3 X6R5G7 ZCCHC11 Terminal uridylyltransferase 4 1 0 CALQNS(1)PR;CALQNS(1)PR ; 112.71 0.010503 48994000 9263.7 7393.4 8733.5 8266.5 8856 9710.4 7515.2 4547.9 9523 8039.9 TRUE FALSE FALSE 8530.46837 8032.452552 9057.171193 8232.295413 8750.397984 7696.353581 7726.056286 5934.533774 8478.350725 8319.285927 1.025384684 0.965521876 1.088695745 0.989543512 1.051820801 0.925121897 0.92869224 0.713346533 1.019120006 1 13.02224399 -3.616357386 0.983510015 1.014756567 1.81E-12 0.851016912 0.038044656 1.410725152 0.428248243 0.005225541 2.060912551 0.000241904 3.616357386 -1.014756567 CALSS(ph)PSLAFTPPIK ddPTM_HeLa_Curcumin_4h_R1 1 CALSSPSLAFTPPIK 15 0 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 0 CALS(0.016)S(0.536)PS(0.368)LAFT(0.081)PPIK 180.3 5.73E-05 26284000 3533.2 2781.8 3072.7 2743.2 2664.6 3913.7 2974.5 2443.5 3222.2 3486.7 TRUE FALSE FALSE 3253.543492 3022.246397 3186.576965 2731.849365 2632.826385 3101.954504 3057.956465 3188.511902 2868.732722 3607.862565 0.901792525 0.837683349 0.88323125 0.757193301 0.729746862 0.859776238 0.847581195 0.883767561 0.795133592 1 11.81692867 -7.879476267 0.677829392 0.987456973 0.818988178 0 0.076886497 0.287377218 0.296254542 0.01875466 0.01419772 1.32E-08 7.879476267 -0.168468795 CALSSPSLAFT(ph)PPIK ddPTM_HeLa_Curcumin_4h_R1 1 CALSSPSLAFTPPIK 15 0 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 0 CALSSPS(0.003)LAFT(0.997)PPIK 136.99 0.0017169 22320000 1473.3 1261.1 1313.7 1253.4 1205 1776.5 1385.1 1016.6 1627.9 1633.7 TRUE FALSE FALSE 1356.68675 1370.103865 1362.386878 1248.213763 1190.631162 1408.033875 1423.962178 1326.55666 1449.323443 1690.470953 0.802549578 0.810486487 0.805921495 0.73838226 0.704319207 0.832924027 0.842346433 0.784726089 0.857348918 1 10.72320951 -9.064429608 0.579146761 1.023815251 0.78411488 0.398464376 0.058193979 0.378280816 0.202305976 0.047490576 0.010282507 8.62E-10 9.064429608 -0.239700371 CAPPS(ph)PPPPVEPATQEEAERR ddPTM_HeLa_Curcumin_4h_R1 1 CAPPSPPPPVEPATQEEAERR 21 1 Q6IQ19;Q6IQ19-3;Q6IQ19-4 Q6IQ19 CCSAP "Centriole, cilia and spindle-associated protein" 1 0 CAPPS(0.978)PPPPVEPAT(0.022)QEEAERR 75.054 0.00096515 4188800 1431 1264 1745.1 1684.4 1535.7 1699.2 1485.1 858.32 1551.7 1477.3 TRUE FALSE FALSE 1317.73484 1373.254528 1809.774941 1677.430399 1517.38778 1346.766766 1526.767909 1120.017817 1381.482392 1528.636065 0.86203307 0.898352825 1.183914852 1.097337972 0.99264162 0.881025116 0.998777894 0.732690954 0.903735313 1 10.57802926 -4.25560913 24.02393257 0.962100309 0.732690778 0.353689774 0.097602347 378.5972377 1559952.364 0.0149479 0.175427593 5.55E-05 4.25560913 -0.229409532 CAPSAGS(ph)PAAAVGR ddPTM_HeLa_Curcumin_4h_R1 2 CAPSAGSPAAAVGR 14 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 0 CAPS(0.027)AGS(0.973)PAAAVGR;CAPS(0.002)AGS(0.998)PAAAVGR ; 155.14 0.00039905 70358000 2167.75 2335.3 2363.65 1727.97 2262.15 2769.7 1402.58 1386.27 2362.1 2160.7 TRUE FALSE FALSE 1996.1703 2537.152926 2451.248948 1720.820118 2235.175339 2195.232999 1441.93262 1808.937341 2102.98354 2235.784164 0.892827819 1.134793316 1.096371013 0.769671843 0.99972769 0.981862666 0.64493373 0.809084066 0.940602216 1 11.12656521 -4.771165645 24.99995151 0.964620446 0.727008893 0.48158802 0.103105414 115.6269432 297205.2399 0.014429644 0.044079401 1.69E-05 4.771165645 -0.237611553 CATITPDEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 CATITPDEKR 10 1 C9J4N6;O75874 C9J4N6 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic 0 1 CATITPDEK(1)R 99.973 0.00050685 0 853.32 753.91 613.62 698.02 791.67 1182.4 972.87 712.72 1108.2 627.95 FALSE TRUE FALSE 785.7788216 819.074621 636.361297 695.1317782 782.2298523 937.1569116 1000.166114 930.025047 986.6332326 649.7712158 1.209316145 1.260558488 0.979362092 1.069810052 1.20385427 1.442287514 1.53925888 1.431311552 1.518431732 1 9.343788025 -5.325774371 2.758719816 1.103340209 1.488245423 0.387423717 0.15561344 0.108230543 1.606823724 0.01513094 0.039715484 4.72E-06 5.325774371 0.384905214 CATPVIIDEILPSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 CATPVIIDEILPSKK 15 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 0 1 CATPVIIDEILPSK(1)K 182.71 2.75E-44 0 118.53 215.11 139.92 83.038 105.81 138.34 129.77 154.29 117.44 194.74 FALSE TRUE FALSE 109.1482254 233.7031499 145.1055583 82.69441076 104.5482849 109.6467246 133.4109969 201.3323107 104.5571258 201.5072005 0.541659182 1.159775677 0.720101108 0.410379433 0.518831509 0.544133035 0.662065656 0.999132092 0.518875383 1 7.654687582 -6.520234452 24.99426513 0.812120684 0.612956783 0.117672181 0.228359754 169.4022386 1601220.924 0.038202075 0.054583289 3.02E-07 6.520234452 -0.199163901 CCLTYCFNKPEDK ddPTM_HeLa_Curcumin_4h_R1 2 CCLTYCFNKPEDK 13 1 P62979;A0A2R8Y422 P62979 RPS27A Ubiquitin-40S ribosomal protein S27a;Ubiquitin;40S ribosomal protein S27a 0 0 ; ; 136.27 0.00041907 7087800 3119.11 2763.19 3286.72 3254.25 3109.48 4210.4 2682.84 2866.44 3627.5 3214.34 FALSE FALSE TRUE 2872.229152 3002.027831 3408.528734 3240.784776 3072.401482 3337.115579 2758.11327 3740.404361 3229.572326 3326.038076 0.863558711 0.902583724 1.024801478 0.974367912 0.923742126 1.00333054 0.829248856 1.124582544 0.970996799 1 11.69958897 -6.78638075 24.98870432 0.931295205 0.971405037 0.06868672 0.078442231 578.4136953 579509.5564 0.013134386 0.017265834 1.64E-07 6.78638075 0.040109832 CCS(ph)PPNELGFR ddPTM_HeLa_Curcumin_4h_R1 1 CCSPPNELGFR 11 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 0 CCS(1)PPNELGFR 108.98 0.0070783 0 1522.2 1559.5 1407.1 1596.4 1550.1 1996.9 1225.1 916.75 1805.3 1696.9 TRUE FALSE FALSE 1401.716264 1694.296231 1459.248364 1589.79452 1531.61607 1582.72043 1259.473009 1196.262855 1607.263107 1755.867149 0.798304282 0.964934182 0.831069916 0.905418454 0.872284712 0.901389625 0.717294022 0.681294627 0.915367149 1 10.77796798 -13.52287875 0.024935232 2.110784239 1.76E-14 0.440126975 0.072750004 1322.024479 2.653415131 159.1751559 78.7124537 3.00E-14 13.52287875 -2.110784239 CCSGAIIVLT(ph)K ddPTM_HeLa_Curcumin_4h_R1 2 CCSGAIIVLTK 11 0 P14618;P14618-3;B4DNK4 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 1 0 CCSGAIIVLT(1)K;CCSGAIIVLT(1)K ; 112.43 0.016866 47829000 2798.5 1784.59 2455.4 2041.07 2009.45 3749.7 2519.4 1978.13 2028.03 1973.15 TRUE FALSE FALSE 2576.995772 1938.842008 2546.399284 2032.624593 1985.488621 2971.969952 2590.087583 2581.252731 1805.560183 2041.716816 1.262171008 0.949613577 1.247185342 0.995546776 0.972460336 1.455622998 1.268583167 1.264255998 0.884334286 1 10.99556706 -1.000000005 0.020134366 9.87E-15 2.690212699 0.257970105 0.155805804 3857.511027 6.046485574 300.1687582 541.2407613 0.099999999 1.000000005 2.690212699 CCSGAIIVLTK ddPTM_HeLa_Curcumin_4h_R1 2 CCSGAIIVLTK 11 0 P14618;P14618-3;B4DNK4 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 178.08 1.52E-11 26246000 10874.5 7762.4 9145.1 7715.3 8234.8 17823.8 11722.4 10606.3 8777 8699.6 FALSE FALSE TRUE 10013.77185 8433.347267 9484.025451 7683.376133 8136.605388 14126.94296 12051.29899 13840.11204 7814.185059 9001.910452 1.112405184 0.93683972 1.053556964 0.853527279 0.903875397 1.569327204 1.338749042 1.537463866 0.868058519 1 13.1360155 -5.260216921 24.9999828 1.021357985 1.467536953 0.82627847 0.106879984 34.52013463 705944.9375 0.014486238 0.034798407 5.49E-06 5.260216921 0.446178968 NAEK(ac)ELTDR ddPTM_HeLa_Curcumin_4h_R1 2 NAEKELTDR 9 1 Q9UKX7;F2Z3L9;X6RKQ2;B1AHA5;B0QY21 Q9UKX7 NUP50 Nuclear pore complex protein Nup50 0 1 ; NAEK(1)ELTDR;NAEK(1)ELTDR 107.55 0.0043416 5598000 2124.92 2511.3 2001.72 2248.77 2167.98 2689.5 2452.11 6265.6 1995.22 2089.2 FALSE TRUE FALSE 1956.73034 2728.365582 2075.905504 2239.465186 2142.128254 2131.667383 2520.909607 8175.952597 1776.349358 2161.799544 0.905139584 1.262080746 0.960267343 1.035926384 0.990900502 0.986061538 1.166116263 3.78201236 0.821699386 1 11.07801704 -4.259943008 4.434139034 0.988555941 3.979029582 0.98393336 0.106298995 0.015336847 0.739106583 0.013420505 0.143425682 5.50E-05 4.259943008 2.990473641 up CDAVMPPGRS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 CDAVMPPGRSR 11 1 K7EKX9;K7EN83;B4DKV7;Q8TE68-3;Q8TE68 K7EKX9 EPS8L1 Epidermal growth factor receptor kinase substrate 8-like protein 1 1 0 CDAVMPPGRS(1)R 118.77 0.0084896 6332000 303.01 232.48 129.97 308.14 305.67 150.41 137.76 59.57 247.97 0 TRUE FALSE FALSE 279.0264388 252.5745353 134.7868025 306.8649983 302.0250849 119.2132705 141.6251748 77.73261877 220.7683114 0 0 CDENILWLDYK ddPTM_HeLa_Curcumin_4h_R1 4 CDENILWLDYK 11 0 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ;;; ;;; 179.19 8.39E-09 298316800 11271.13 8748.39 11195.93 9524.98 8738.74 11918.1 9301.34 8292.93 9007.84 7057.5 FALSE FALSE TRUE 10379.00817 9504.56185 11610.86101 9485.568157 8634.536233 9446.151715 9562.310567 10821.40618 8019.702489 7302.7476 1.421247007 1.301504909 1.589930482 1.298904012 1.182368159 1.293506531 1.309412716 1.481826673 1.098176047 1 12.83422365 -9.295408525 0.925841836 0.990997054 1.357368016 0.546399788 0.111985682 0.337160864 0.497870115 0.085644853 0.02087232 5.07E-10 9.295408525 0.366370963 CDLISIPK ddPTM_HeLa_Curcumin_4h_R1 2 CDLISIPK 8 0 H0YHL7;B4E3S0;Q9ULV4;Q9ULV4-2;Q9ULV4-3 H0YHL7 CORO1C Coronin;Coronin-1C 0 0 ; ; 119.41 7.63E-05 1119500 3409.6 3330.5 3190.5 3690.7 3500.81 2910.9 2516.1 2186.75 3669.1 2758.62 FALSE FALSE TRUE 3139.726562 3618.37358 3308.742737 3675.428861 3459.065127 2307.146527 2586.694994 2853.480008 3266.60891 2854.48184 1.099928722 1.26761135 1.15913953 1.287599315 1.211801413 0.808254057 0.906187231 0.999649032 1.144378943 1 11.47901317 -5.259061671 24.98918009 1.101760039 0.904845821 0.515252998 0.103893539 184.3424106 1937382.965 0.01784768 0.043197066 5.51E-06 5.259061671 -0.196914218 CEGGVDAALLYAKNMAKYMK ddPTM_HeLa_Curcumin_4h_R1 1 CEGGVDAALLYAKNMAKYMK 20 2 Q92619;F5H1R4;K7ES98;K7EM85;Q92619-2 Q92619 HMHA1 Minor histocompatibility protein HA-1;Minor histocompatibility antigen HA-1 0 0 41.202 0.016107 535630 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 CETS(ph)PPSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 CETSPPSSPR 10 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2;H0YD72;M0QZB5;B1APN9;O75335-2;O75335-1;O75335 A0A2R8Y7R9 PPFIA1;PPFIA4 Liprin-alpha-1;Liprin-alpha-4 2 0 CET(0.389)S(0.611)PPS(0.145)S(0.855)PR 116.74 0.012249 17665000 6385.8 5147.4 5057.1 5921.1 5211.9 6280.2 4435.5 2786.2 6580.9 5755.8 TRUE FALSE FALSE 5880.357192 5592.31832 5244.520575 5896.600057 5149.751497 4977.615728 4559.948192 3635.699554 5858.991735 5955.813622 0.987330626 0.938967986 0.880571641 0.990057855 0.864659612 0.835757471 0.765629767 0.610445488 0.983743298 1 12.54008289 -3.4317723 0.43291342 0.994859434 5.47E-13 0.913671614 0.034749856 1.644981281 0.123215273 0.007797396 0.985067273 0.000370022 3.4317723 -0.994859434 CETS(ph)PPSSPR ddPTM_HeLa_Curcumin_4h_R1 1 CETSPPSSPR 10 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2;H0YD72;M0QZB5;B1APN9;O75335-2;O75335-1;O75335 A0A2R8Y7R9 PPFIA1;PPFIA4 Liprin-alpha-1;Liprin-alpha-4 1 0 CET(0.221)S(0.748)PPS(0.03)S(0.001)PR 102.05 0.011218 11285000 2170.1 1924 1942 2188 2235.2 3401.9 3034.7 2943 2437 2423.3 TRUE FALSE FALSE 1998.334295 2090.301987 2013.972228 2178.946636 2208.5467 2696.307593 3119.845515 3840.307152 2169.667197 2507.509495 0.796939872 0.833616778 0.803176312 0.868968449 0.880773016 1.075293074 1.244200878 1.531522477 0.865267789 1 11.29203945 -4.533763525 1.281867344 0.883573826 1.643441369 0.92940537 0.059649183 0.237933611 0.464959424 0.013017469 0.207048841 2.93E-05 4.533763525 0.759867543 CFIVGADNVGSK ddPTM_HeLa_Curcumin_4h_R1 2 CFIVGADNVGSK 12 0 F8VWS0;P05388-2;Q8NHW5;P05388;G3V210;F8VU65;F8VS58;F8VQY6;F8VPE8;F8VRK7;F8VZS0;F8VWV4 F8VWS0 RPLP0;RPLP0P6 60S acidic ribosomal protein P0;60S acidic ribosomal protein P0-like 0 0 ; ; 229.82 2.43E-38 9706500 9267.7 7169.2 8020.7 7271.6 8454.1 8996.8 8066.9 8749.2 7960.2 7503.1 FALSE FALSE TRUE 8534.151766 7788.873703 8317.954198 7241.512046 8353.290379 7130.762265 8293.235503 11416.7908 7086.985975 7763.832167 1.099218992 1.003225409 1.071372232 0.932723929 1.075923616 0.918459095 1.068188406 1.470509738 0.912820605 1 12.92255322 -4.267184896 4.721414672 1.032285338 1.494199708 0.799761433 0.068597173 0.051221709 3.148513547 0.008210338 0.077131904 5.41E-05 4.267184896 0.461914369 CFNPPPKPEPFQFGQSSQKPPVAGGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 CFNPPPKPEPFQFGQSSQKPPVAGGKK 27 3 Q9H814 Q9H814 PHAX Phosphorylated adapter RNA export protein 0 1 CFNPPPKPEPFQFGQSSQK(0.002)PPVAGGK(0.998)K 80.314 0.00013231 4119000 1741.6 1417.1 1621.4 1234.1 1163.3 1778.9 1379.8 1525 1856.1 1531.3 FALSE TRUE FALSE 1603.750522 1539.58781 1681.49051 1228.993621 1149.428407 1409.936088 1418.513474 1989.96548 1652.490474 1584.512561 1.012141249 0.971647589 1.061203648 0.775628828 0.725414513 0.889823232 0.895236497 1.255884951 1.042901467 1 10.62982338 -6.285642252 24.94687141 1.006562357 0.896468768 0.137486215 0.133673846 1141.260913 1176341.003 0.020166537 0.030814036 5.18E-07 6.285642252 -0.110093589 CGEDDETIPSEYR ddPTM_HeLa_Curcumin_4h_R1 2 CGEDDETIPSEYR 13 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E7EVY3;E9PCH5;P20810-3;F8W7E0;E7EQ12;E7EQA0;H0Y7F0;A0A0A0MR45;H0Y9H6;H0YD33;D6RAA8 P20810-6 CAST Calpastatin 0 0 ; ; 251.43 5.57E-35 16647000 3185 2830.02 2605.81 3002.8 3116.82 3634.1 3011.1 3208.58 3833.3 3240.2 FALSE FALSE TRUE 2932.903889 3074.634318 2702.383611 2990.375209 3079.653957 2880.346695 3095.583362 4186.861272 3412.79658 3352.796709 0.874763412 0.917035712 0.806008788 0.89190472 0.918532862 0.859087784 0.923283942 1.248766816 1.01789547 1 11.7111493 -4.261861896 7.236785745 0.917952076 1.252972556 0.742630949 0.059382704 0.043946142 19.56606795 0.008957667 0.071958895 5.47E-05 4.261861896 0.33502048 S(ph)ASASHQADIK ddPTM_HeLa_Curcumin_4h_R1 1 SASASHQADIK 11 0 C9JXK0;A0A494C1L1;Q14739 C9JXK0 LBR Lamin-B receptor 1 0 S(0.788)AS(0.175)AS(0.038)HQADIK 81.185 0.012619 15818000 7015.8 7281 7189.9 9485 8296.6 7907.6 2325.5 1303.8 12933 9859.8 TRUE FALSE FALSE 6460.492027 7910.337196 7456.364019 9445.753583 8197.668464 6267.474623 2390.747271 1701.322618 11514.28226 10202.42732 0.63323088 0.775338746 0.73084216 0.92583395 0.803501776 0.614312107 0.234331223 0.166756652 1.12858263 1 13.31662481 -4.856209409 2.254735357 0.818091988 0.159321412 0.782749038 0.136290296 0.113926502 1.120175776 0.020344098 0.092309591 1.39E-05 4.856209409 -0.658770576 down CGGVEQASSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 CGGVEQASSSPR 12 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5;H7C1I7;Q5VZL5-3 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 0 CGGVEQAS(0.002)S(0.033)S(0.965)PR;CGGVEQAS(0.005)S(0.117)S(0.878)PR ; 133.88 0.001972 181021000 12553.6 14255.1 14969.6 16740.1 13469.5 14613.3 10636.7 6231.1 19357.6 17307.7 TRUE FALSE FALSE 11559.96931 15487.24732 15524.38654 16670.8339 13308.88501 11582.33685 10935.13717 8130.933706 17234.11971 17909.14129 0.645478704 0.864767723 0.86684148 0.930856127 0.743133621 0.64672765 0.610589698 0.45401025 0.962308546 1 14.12840854 -13.52287872 0.042768596 2.202874423 4.30E-13 0.546316833 0.114849395 472.6806838 1.610616214 74.86923583 22.53626857 3.00E-14 13.52287872 -2.202874423 CGQEEHDVLLSNEEDRK ddPTM_HeLa_Curcumin_4h_R1 1 CGQEEHDVLLSNEEDRK 17 1 Q9UGI8;Q9UGI8-2 Q9UGI8 TES Testin 0 0 107.46 0.00038962 7857400 9294.8 7820.5 7671.5 8276 8935.6 11466 8142.2 8927.7 9571.9 7796.9 FALSE FALSE TRUE 8559.106772 8496.469173 7955.812539 8241.756105 8829.048806 9087.822352 8370.648218 11649.71463 8521.886518 8067.841695 1.06089176 1.053127899 0.986114111 1.021556498 1.094350774 1.126425467 1.037532532 1.443969165 1.056278351 1 12.97796706 -1.90560316 1.283445388 1.033962665 199.9992623 0.869498421 0.045159794 184.3222831 0.795356103 0.006817971 107429.2798 0.012427874 1.90560316 198.9652996 CGS(ph)PSDSSTTEEMEVAVSK ddPTM_HeLa_Curcumin_4h_R1 1 CGSPSDSSTTEEMEVAVSK 19 0 P31751;P31751-2;M0R0P9;C9JHS6;J3QKW1;J3QLS6;M0QZK3;M0R275 P31751 AKT2 RAC-beta serine/threonine-protein kinase 1 0 CGS(0.856)PS(0.144)DSSTTEEMEVAVSK 220.64 1.31E-18 10747000 2567.6 1864.5 1642.2 2165.6 1755 2097.6 1239.4 1218.2 2301.5 1897 TRUE FALSE FALSE 2364.371751 2025.659072 1703.061377 2156.639321 1734.072771 1662.534115 1274.174228 1589.623572 2049.031208 1962.920609 1.204517259 1.031961793 0.867616025 1.098689021 0.883414624 0.846969616 0.649121632 0.809825708 1.04386861 1 10.93878611 -5.496024752 0.837009268 1.088196603 0.704300825 0.618426001 0.094999803 0.375928589 0.446155015 0.018931143 0.090334965 3.19E-06 5.496024752 -0.383895778 CGSGPVHISGQHLVAVEEDAES(ph)EDEEEEDVK ddPTM_HeLa_Curcumin_4h_R1 1 CGSGPVHISGQHLVAVEEDAESEDEEEEDVK 31 0 P06748;P06748-3;P06748-2;E5RI98 P06748 NPM1 Nucleophosmin 1 0 CGSGPVHISGQHLVAVEEDAES(1)EDEEEEDVK 107.36 4.19E-11 230960000 2396.6 1650 2049.3 2053.6 2999.8 3409.1 2551.5 2087.7 2561.9 1900.9 TRUE FALSE FALSE 2206.906581 1792.618648 2125.248861 2045.102747 2964.029344 2702.014232 2623.088223 2724.230119 2280.86598 1966.956134 1.121990747 0.911366866 1.080475982 1.039729719 1.506911768 1.373703351 1.333577388 1.384997903 1.159591686 1 10.94174907 -5.772442973 24.98378338 1.047549845 1.393203708 0.835636296 0.075484684 57.15008627 129760.048 0.010732493 0.019588903 1.69E-06 5.772442973 0.345653863 CGSPSDS(ph)STTEEMEVAVSK ddPTM_HeLa_Curcumin_4h_R1 1 CGSPSDSSTTEEMEVAVSK 19 0 P31751;P31751-2;M0R0P9;C9JHS6;J3QKW1;J3QLS6;M0QZK3;M0R275 P31751 AKT2 RAC-beta serine/threonine-protein kinase 1 0 CGS(0.11)PS(0.097)DS(0.365)S(0.365)T(0.055)T(0.007)EEMEVAVSK 84.718 0.0038738 5703500 2961.2 1938.1 2266.1 2628.8 2461.4 2882 2198.7 1829.4 2896.9 2396.1 TRUE FALSE FALSE 2726.817895 2105.620728 2350.083659 2617.922722 2432.049413 2284.240713 2260.389605 2387.175638 2579.117318 2479.364297 1.09980526 0.849258308 0.947857345 1.055884658 0.980916526 0.921300963 0.911681114 0.962817623 1.040233305 1 11.27575455 -7.280477829 24.99371154 1.047130261 0.950261155 0.4102544 0.054618406 675.0017086 886141.3298 0.010677408 0.012220912 5.24E-08 7.280477829 -0.096869106 CIAAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 CIAAKK 6 1 Q01780-2;Q01780 Q01780-2 EXOSC10 Exosome component 10 0 1 ; CIAAK(1)K;CIAAK(1)K 106.84 0.010351 29386000 18218.5 17011.7 18795.2 15280.3 14826.9 19805.5 14704.2 13415.9 16574.5 15252.2 FALSE TRUE FALSE 16776.4865 18482.11555 19491.76665 15217.07417 14650.0989 15697.61605 15116.76028 17506.34615 14756.31882 15782.21281 1.062999637 1.171072508 1.235046497 0.964191419 0.928266465 0.99463974 0.957835283 1.109245348 0.934996821 1 13.94601188 CIACQAAKLS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 CIACQAAKLSPR 12 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 0 CIACQAAKLS(1)PR;CIACQAAKLS(1)PR ; 124.12 0.001829 0 2392.75 1473.63 1916.04 1846.01 1559.02 1838.01 1257.9 1167.51 1951.33 1986.67 TRUE FALSE FALSE 2203.361313 1601.004011 1987.050128 1838.3717 1540.429705 1456.786007 1293.193289 1523.478424 1737.273981 2055.706635 1.071826726 0.778809575 0.966601992 0.894277262 0.74934316 0.708654622 0.629074824 0.741097197 0.845098202 1 11.00541868 -6.043930953 0.694034551 1.030802967 0.657782346 0.504775495 0.094886737 0.263409741 0.237699303 0.015787955 0.048754145 9.04E-07 6.043930953 -0.373020621 CIFMSETQS(ph)SPTK ddPTM_HeLa_Curcumin_4h_R1 1 CIFMSETQSSPTK 13 0 B4DGW0;A0A087WUY7;O75928-2;O75928 B4DGW0 PIAS2 E3 SUMO-protein ligase PIAS2 1 0 CIFMSET(0.001)QS(0.699)S(0.28)PT(0.02)K 137.95 0.00052981 0 2028.7 2014.5 2076.5 1842.8 2422.2 2793.1 1508.4 1004.9 2138.9 1908.4 TRUE FALSE FALSE 1868.126254 2188.624404 2153.456917 1835.174982 2393.316847 2213.779575 1550.721644 1311.289384 1904.268021 1974.716758 0.946022384 1.108323204 1.090514327 0.929335802 1.211979813 1.121061826 0.785288137 0.664039224 0.964324637 1 10.94743002 -4.600473711 5.008894693 1.013036154 0.690651843 0.665396735 0.090441882 0.093121507 4.074950359 0.013552421 0.055147033 2.51E-05 4.600473711 -0.32238431 STDEYS(ph)EADEEEEEEEGKPSR ddPTM_HeLa_Curcumin_4h_R1 2 STDEYSEADEEEEEEEGKPSR 21 1 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 0 S(0.001)T(0.001)DEYS(0.997)EADEEEEEEEGKPSR;S(0.006)T(0.006)DEYS(0.988)EADEEEEEEEGKPSR ; 160.84 3.50E-07 100955000 3920.5 2843 3186.1 3298.5 3246.4 3702.8 1573.74 1198.76 3477.4 3342.6 TRUE FALSE FALSE 3610.188288 3088.736252 3304.179669 3284.851681 3207.6888 2934.797541 1617.894909 1564.256406 3095.93792 3458.755101 1.04378257 0.893019645 0.95530894 0.949720806 0.927411368 0.848512674 0.467767986 0.452259949 0.895101801 1 11.75603715 -4.85164036 1.833605861 0.997974916 0.410283563 0.908457704 0.06011833 0.066243119 0.409044127 0.008320802 0.044989051 1.41E-05 4.85164036 -0.587691354 down CIHSFQNLGIQCVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 CIHSFQNLGIQCVKK 15 1 Q2TAM5;E9PKH5;A0A087X0W8;Q04206-2;Q04206-3;Q04206-4;Q04206;E9PRX2;E9PMD5;E9PI38;E9PQS6;E9PKV4;A0A087WVP0 Q2TAM5 RELA Transcription factor p65 0 1 CIHSFQNLGIQCVK(1)K 69.045 0.011083 1351300 330.17 351.56 269.52 255.83 420.97 695.53 344.49 423.36 377.94 424.57 FALSE TRUE FALSE 304.0366961 381.9472799 279.5086483 254.7714432 415.9502077 551.2692378 354.1554623 552.4405151 336.4809276 439.3237759 0.692056093 0.869398154 0.636224725 0.579917267 0.946796487 1.25481312 0.806137709 1.257479211 0.765906482 1 8.779140769 -5.522671868 24.99999951 0.81491933 1.080253139 0.447961144 0.167002305 6.831668694 825538.6763 0.026817623 0.05410351 3.00E-06 5.522671868 0.265333809 CIIPNHEKK ddPTM_HeLa_Curcumin_4h_R1 1 CIIPNHEKK 9 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 38.293 0.017945 6650700 5410.5 3998.8 4449.9 4326.2 4589.2 7414.8 3515.5 3576.7 5621.4 5034.1 FALSE FALSE TRUE 4982.253216 4344.438454 4614.817209 4308.299331 4534.476787 5876.886898 3614.135469 4667.219365 5004.746484 5209.0346 0.956463836 0.834019888 0.88592562 0.82708211 0.870502336 1.128210378 0.693820592 0.89598548 0.960781962 1 12.3468003 -7.443428423 4.087489119 0.981738729 0.877522111 0.159743331 0.101226518 0.281203907 8.39176051 0.017019906 0.019073112 3.60E-08 7.443428423 -0.104216617 CIPALDSLTPANEDQK ddPTM_HeLa_Curcumin_4h_R1 1 CIPALDSLTPANEDQK 16 0 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 235.25 8.59E-37 707270 397.07 344.18 291.12 296.38 210.2 663.58 415.43 389.52 308.66 342.15 FALSE FALSE TRUE 365.6414905 373.9293856 301.9091633 295.1536581 207.6935023 525.9460279 427.0858477 508.2828549 274.8007702 354.039687 1.032769782 1.056179291 0.852755141 0.833673932 0.58663904 1.485556697 1.206321956 1.435666321 0.776186344 1 8.467767282 -5.234484933 24.99982445 0.967696255 1.358895719 0.631086768 0.164735263 422.9888196 392314.9406 0.02229947 0.056836076 5.83E-06 5.234484933 0.391199463 CIS(ph)PEGVNGNR ddPTM_HeLa_Curcumin_4h_R1 2 CISPEGVNGNR 11 0 G5E9L9;Q8N568-2;Q8N568;A0A0U1RR70;Q8N568-3 G5E9L9 DCLK2 Serine/threonine-protein kinase DCLK2 1 0 CIS(1)PEGVNGNR;CIS(1)PEGVNGNR ; 137.4 0.0017376 25394000 3409 3305.5 3338.3 3528 3189.4 3050.7 1858.3 1591.48 3886.8 3130 TRUE FALSE FALSE 3139.174053 3591.212691 3462.020335 3513.402071 3151.368488 2417.950432 1910.438897 2076.714926 3460.427764 3238.767267 0.969249654 1.108820855 1.068931494 1.084796091 0.973014801 0.746565045 0.589866063 0.641205358 1.068439773 1 11.66122909 -5.145425303 2.625862344 1.009465954 0.618116623 0.920350271 0.0516705 0.062745 0.832345005 0.008267462 0.025396679 7.15E-06 5.145425303 -0.391349332 CKAGMS(ph)NPALTMENET(ph) ddPTM_HeLa_Curcumin_4h_R1 1 CKAGMSNPALTMENET 16 1 Q9UIJ5 Q9UIJ5 ZDHHC2 Palmitoyltransferase ZDHHC2 2 0 CKAGMS(0.921)NPALT(0.162)MENET(0.917) 53.08 0.016379 10576000 1968 1898 1664.5 2215.1 2283.7 935.88 1451.5 1762.6 2093.4 2207 TRUE FALSE FALSE 1812.230723 2062.054663 1726.187834 2205.934503 2256.468369 741.7679385 1492.225183 2300.008626 1863.759257 2283.693086 0.79355266 0.902947369 0.755875579 0.965950511 0.988078645 0.324810695 0.653426326 1.007144366 0.816116346 1 11.15715306 -13.52287874 0.13040698 1.749856579 0.684920862 0.025611923 0.197825201 114.0412161 1.053917807 22.26709453 0.703278208 3.00E-14 13.52287874 -1.064935717 CKDDEFTHLYTLIVRPDNTYEVK ddPTM_HeLa_Curcumin_4h_R1 2 CKDDEFTHLYTLIVRPDNTYEVK 23 2 P27797;K7EJB9 P27797 CALR Calreticulin 0 0 ; ; 93.5 4.99E-05 106996000 9577.3 7213.4 9172.2 9061.7 9033.3 12206 8917.5 7860.7 9716 9082.9 FALSE FALSE TRUE 8819.246599 7836.894154 9512.129801 9024.205086 8925.583797 9674.33801 9167.70105 10257.39124 8650.179108 9398.530099 0.938364458 0.833842534 1.012086965 0.960171962 0.949678695 1.029345856 0.975439878 1.091382497 0.920375741 1 13.19821943 -5.256893598 24.07435726 0.960846195 1.026394465 0.323800173 0.054208437 266.9144521 1413560.546 0.007713719 0.018947782 5.53E-06 5.256893598 0.06554827 CKDIDECSQSPQPCGPNSSCKNLSGRYK ddPTM_HeLa_Curcumin_4h_R1 1 CKDIDECSQSPQPCGPNSSCKNLSGRYK 28 3 M0R2G7;Q14246-4;Q14246-2;Q14246 M0R2G7 ADGRE1;EMR1 EGF-like module-containing mucin-like hormone receptor-like 1 0 0 32.04 0.019494 7415600 1305 1494 1777.2 1706.1 2746.7 1886.4 1479.8 1481.9 2479.1 1508.5 FALSE FALSE TRUE 1201.707873 1623.134703 1843.064595 1699.04061 2713.947396 1495.139376 1521.319205 1933.724488 2207.148932 1560.920263 0.769871403 1.039857539 1.180755122 1.088486485 1.738684199 0.957857625 0.974629673 1.238836175 1.414004921 1 10.60818113 -6.942266682 3.319325216 0.891311883 1.195669775 0 0.267414841 0.231199346 5.227283575 0.036008731 0.047534338 1.14E-07 6.942266682 0.304357893 CKECRKT(ph)FCMLS(ph)HLT(ph)QHK ddPTM_HeLa_Curcumin_4h_R1 1 CKECRKTFCMLSHLTQHK 18 3 A0A087X2A5;Q03924 A0A087X2A5 ZNF117 Zinc finger protein 117 3 0 CKECRKT(1)FCMLS(1)HLT(1)QHK 42.314 0.019707 5940700 295.56 311.74 235.43 398.17 334.08 369.04 378.52 190.57 282 367.83 TRUE FALSE FALSE 272.1661141 338.6854165 244.1552429 396.522478 330.0963142 292.4969441 389.1402525 248.6739157 251.0653055 380.6120651 0.715074847 0.889844142 0.641480566 1.041802177 0.867277589 0.768490993 1.022406508 0.653352688 0.659635699 1 8.572177484 -9.57733473 1.37242438 0.999607445 0.818463038 0 0.167512622 0.520837955 1.765007365 0.086301247 0.02035698 2.65E-10 9.57733473 -0.181144407 CLATCT(ph)RDGKPS(ph)ARMLLLK ddPTM_HeLa_Curcumin_4h_R1 1 CLATCTRDGKPSARMLLLK 19 3 J3QQV6 J3QQV6 PNPO 2 0 CLAT(0.149)CT(0.851)RDGKPS(1)ARMLLLK 67.11 0.0040807 0 1487.4 1190.1 1694.5 2168.2 1889.8 1784.8 1571.5 1483.3 1732.1 1688.4 TRUE FALSE FALSE 1369.670721 1292.966941 1757.299661 2159.228563 1867.265369 1414.612361 1615.592061 1935.551342 1542.092964 1747.071774 0.783980796 0.740076601 1.005854302 1.235912911 1.068797171 0.809704777 0.924742809 1.107883128 0.882672931 1 10.77072316 -6.556340401 24.62507447 0.882805069 1.024306775 0.309854448 0.123927754 205.5144086 151241.2109 0.022834817 0.03229343 2.78E-07 6.556340401 0.141501705 CLATGPGIASTVK ddPTM_HeLa_Curcumin_4h_R1 1 CLATGPGIASTVK 13 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 112.94 0.0014999 2510900 2842.6 2201 2593.6 2569 2756.4 3614.8 2219.5 3006.7 2579.4 2331.7 FALSE FALSE TRUE 2617.605211 2391.244633 2689.721098 2558.370159 2723.53173 2865.049733 2281.773197 3923.428989 2296.446273 2412.726401 1.08491589 0.991096475 1.11480568 1.060364804 1.128819135 1.187473943 0.945723972 1.626139204 0.951805506 1 11.23644861 -4.254712925 24.99577171 1.054931633 1.626139464 0.838487045 0.075626749 204.4670467 759787.8927 0.009515102 0.123209117 5.56E-05 4.254712925 0.571207831 CLELFSELAEDKENYKK ddPTM_HeLa_Curcumin_4h_R1 2 CLELFSELAEDKENYKK 17 2 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 0 ; ; 81.789 0.0032765 74614000 6462.6 4661.8 6366.9 4717 4464.7 5248.5 3947.5 4173.8 4558.2 5150.2 FALSE FALSE TRUE 5951.078391 5064.745219 6602.862915 4697.482304 4411.461368 4159.901937 4058.256226 5446.372406 4058.176864 5329.169067 1.116699117 0.950381787 1.239004211 0.881466181 0.827795349 0.780591099 0.761517635 1.021992798 0.761502743 1 12.37969489 -6.051242107 12.17243753 1.059582358 0.839177362 0.224959048 0.135201838 0.78166152 185.2188132 0.014139768 0.023474659 8.89E-07 6.051242107 -0.220404997 CLIKSPDRLADINY(ph)EGR ddPTM_HeLa_Curcumin_4h_R1 1 CLIKSPDRLADINYEGR 17 2 A0A3B3ITD8;P52948-6;P52948-2;P52948-5;P52948;P52948-4;P52948-3 A0A3B3ITD8 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 0 CLIKS(0.003)PDRLADINY(0.997)EGR 73.758 0.016079 84823000 1339.7 1104.9 1004.6 1152.4 1351.6 1603.8 1030.3 752.74 1661.4 1201.4 TRUE FALSE FALSE 1233.661331 1200.402633 1041.83136 1147.631674 1335.483053 1271.153801 1059.207445 982.2469608 1479.148577 1243.148561 0.992368387 0.965614787 0.838058614 0.923165348 1.074274705 1.02252767 0.852036095 0.790128382 1.189840558 1 10.279783 -4.628134073 4.50494892 0.984380609 0.803823763 0.394708378 0.088358501 0.117322758 3.985161289 0.008856745 0.03672806 2.35E-05 4.628134073 -0.180556845 CLLEMT(ph)DDDANRIAQVTK ddPTM_HeLa_Curcumin_4h_R1 2 CLLEMTDDDANRIAQVTK 18 1 S4R400;Q5VW36 S4R400 FOCAD Focadhesin 1 0 CLLEMT(1)DDDANRIAQVTK;CLLEMT(1)DDDANRIAQVTK ; 59.342 0.016767 19497600 3688 4099.8 4074.3 4444.1 4758.7 5062.6 4056.7 4479.1 6075.2 5043.4 TRUE FALSE FALSE 3396.090908 4454.168444 4225.297142 4425.711492 4701.955611 4012.559693 4170.520084 5844.756971 5408.765759 5218.657775 0.650759459 0.853508438 0.809652084 0.848055512 0.900989452 0.768887301 0.799155696 1.119973224 1.036428521 1 12.34946308 -4.257482796 23.9360905 0.830591806 1.11997343 0.346074661 0.106970884 203.4815987 1230904.332 0.01736476 0.174271149 5.53E-05 4.257482796 0.289381624 CLLTFPSPEQLEIS(ph)GIIHMNK ddPTM_HeLa_Curcumin_4h_R1 1 CLLTFPSPEQLEISGIIHMNK 21 0 A0A096LNH2 A0A096LNH2 EFCAB8 1 0 CLLT(0.01)FPS(0.041)PEQLEIS(0.949)GIIHMNK 48.314 0.018433 24286000 1314.6 972.59 837.81 1317 1451.9 1830.1 2013.1 733.27 1383.9 1029.3 TRUE FALSE FALSE 1210.548023 1056.656346 868.8599756 1311.550603 1434.587041 1450.516631 2069.582168 956.8406474 1232.089632 1065.068098 1.136592134 0.992102146 0.8157788 1.231424174 1.346943959 1.361900364 1.943145392 0.898384478 1.156817704 1 10.05672996 -5.851723074 2.604327454 1.042334667 1.436984545 0.310098195 0.252944901 0.223342934 3.078237699 0.034762296 0.069575999 1.41E-06 5.851723074 0.394649878 CLPTSDS(ph)SPEPQQPPEDR ddPTM_HeLa_Curcumin_4h_R1 1 CLPTSDSSPEPQQPPEDR 18 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 0 CLPT(0.001)S(0.004)DS(0.498)S(0.498)PEPQQPPEDR 205.66 3.40E-12 11498000 983.33 779.54 926.66 839.29 787.04 1203.4 821.71 943.11 1009.1 1052.8 TRUE FALSE FALSE 905.4983929 846.919964 961.0028348 835.8172404 777.655062 953.8012749 844.7649711 1230.659897 898.4042546 1089.384722 0.831201664 0.777429633 0.88215193 0.767237895 0.713847961 0.875541263 0.775451458 1.129683456 0.824689604 1 10.08929782 -9.08681581 0.836366549 1.001238665 0.83536235 0 0.120468891 0.684275636 0.859987914 0.070143024 0.020308247 8.19E-10 9.08681581 -0.165876315 CLPTSDSS(ph)PEPQQPPEDR ddPTM_HeLa_Curcumin_4h_R1 1 CLPTSDSSPEPQQPPEDR 18 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 0 CLPTSDS(0.128)S(0.872)PEPQQPPEDR 251.28 8.27E-42 12439000 1342 1217.2 1047 1196.4 1047.8 1325.2 1172.8 1104.1 1310.7 1061.9 TRUE FALSE FALSE 1235.779284 1322.409344 1085.802741 1191.449614 1035.305669 1050.338582 1205.705612 1440.735007 1166.919489 1098.800946 1.124661649 1.203502189 0.988170555 1.084317972 0.942214032 0.955895229 1.097292113 1.311188357 1.061993524 1 10.10171434 -4.288612201 3.896350674 1.052634715 1.329410637 0.520008608 0.076040057 0.151880983 4.518574747 0.011581256 0.113234592 5.15E-05 4.288612201 0.276775922 CLS(ph)TTPPGDMAHAR ddPTM_HeLa_Curcumin_4h_R1 2 CLSTTPPGDMAHAR 14 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 CLS(0.949)T(0.039)T(0.012)PPGDMAHAR;CLS(0.973)T(0.026)T(0.001)PPGDMAHAR ; 79.317 0.011955 13516700 4296.2 3853.6 3613.8 3959.5 4256.7 5149.9 3825.7 2323.1 4474.2 3767.6 TRUE FALSE FALSE 3956.151237 4186.688013 3747.730607 3943.116638 4205.941633 4081.752689 3933.038846 3031.402496 3983.391454 3898.52382 1.014781856 1.073916233 0.961320433 1.011438386 1.078854927 1.046999551 1.008853358 0.77757701 1.021769172 1 11.92871223 -4.262218228 5.950011631 1.016613672 0.771011461 0.82553354 0.03387127 0.040738284 6.767400539 0.004723034 0.040365152 5.47E-05 4.262218228 -0.245602211 CLSAAEEK ddPTM_HeLa_Curcumin_4h_R1 2 CLSAAEEK 8 0 A0A087WWU8;P06753-2;P06753-3;P06753-6;J3KN67;A0A494C0P6;A0A2R2Y2Q3 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 0 ; ; 111.95 0.0054204 10879200 6595.4 6018.2 6359.8 5355.8 6108.7 7809.9 5746.6 5685.7 6446.3 6763.6 FALSE FALSE TRUE 6073.367131 6538.386391 6595.499783 5333.639119 6035.857742 6190.038704 5907.83413 7419.243756 5739.157018 6998.634597 0.867793145 0.934237429 0.942398077 0.762097098 0.862433616 0.884463765 0.84414096 1.060098746 0.820039529 1 12.77285777 -9.369844751 0.807314181 1.009482493 0.887900666 0 0.092104935 0.883616033 0.896754975 0.07178018 0.013730187 4.27E-10 9.369844751 -0.121581828 CLSTT(ph)PPGDMAHAR ddPTM_HeLa_Curcumin_4h_R1 1 CLSTTPPGDMAHAR 14 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 CLS(0.018)T(0.026)T(0.955)PPGDMAHAR 145.86 0.00058753 25659000 4469.3 3441.4 4126.2 3919.2 4210.9 5228.5 3574.3 1847.9 4337.1 3437 TRUE FALSE FALSE 4115.550189 3738.859281 4279.120602 3902.983389 4160.687768 4144.050163 3674.585238 2411.316203 3861.330981 3556.435494 1.157212101 1.051293996 1.203204897 1.09744248 1.169903904 1.165225735 1.033221394 0.678014885 1.085730639 1 11.79621628 -4.275528254 3.568875394 1.09680258 0.635395648 0.82060199 0.060689324 0.104429013 2.372892456 0.010572437 0.125962977 5.30E-05 4.275528254 -0.461406931 CLYASVLTAQPR ddPTM_HeLa_Curcumin_4h_R1 2 CLYASVLTAQPR 12 0 P13639 P13639 EEF2 Elongation factor 2 0 0 ; ; 191.4 5.62E-14 13949600 2660 1711.62 2565.7 1470.76 2103.22 3459.9 2345.91 2316.85 1938.69 2362.6 FALSE FALSE TRUE 2449.458193 1859.564806 2660.787099 1464.674385 2078.140475 2742.277739 2411.729921 3023.2469 1726.020557 2444.700174 1.001946259 0.76065148 1.088389949 0.599122297 0.850059446 1.121723542 0.98651358 1.236653448 0.706025457 1 11.25544182 -2.501521387 13.81925396 0.974544284 1.084297584 0 0.194719425 0 0 0.02201368 0 0.003151219 2.501521387 0.1097533 CNAEY(ph)VS(ph)S(ph)T(ph)LSLRGGGS(ph)SGALR ddPTM_HeLa_Curcumin_4h_R1 1 CNAEYVSSTLSLRGGGSSGALR 22 1 F8W6J7;Q6ZVN8 F8W6J7 HFE2 Hemojuvelin 5 0 CNAEY(0.909)VS(0.909)S(0.915)T(0.634)LS(0.634)LRGGGS(0.519)S(0.481)GALR 44.596 0.015631 1372900 1716.2 1504.6 1419.4 1511.5 1348.5 1605.8 1234.4 1123.1 1902.4 1472.2 TRUE FALSE FALSE 1580.360959 1634.65092 1472.004213 1505.245813 1332.420018 1272.738979 1269.033942 1465.52802 1693.71148 1523.35884 1.037418707 1.073057034 0.966288555 0.988109809 0.874659327 0.835482058 0.833049908 0.962037296 1.111826994 1 10.57304011 -5.873256848 2.287101625 1.019622933 0.867871039 0.681364922 0.051269267 0.114454839 1.216523166 0.006364651 0.012910014 1.34E-06 5.873256848 -0.151751894 CNEIINWLDKNQTAEKEEFEHQQK ddPTM_HeLa_Curcumin_4h_R1 1 CNEIINWLDKNQTAEKEEFEHQQK 24 2 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65;E9PM13 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 41.904 0.018576 40981000 2790.6 2485.4 2453.3 2571.6 2428.5 3037 2871.3 2577.6 2875.8 2144 FALSE FALSE TRUE 2569.721065 2700.226901 2544.221456 2560.959401 2399.541724 2407.091966 2951.86095 3363.498374 2560.331935 2218.50384 1.158312651 1.217138709 1.146818594 1.154363294 1.081603592 1.085006896 1.330563823 1.516111134 1.154080461 1 11.11537134 -4.546206368 2.56626286 1.097715748 1.515378499 0.798242483 0.062049779 0.119385651 1.39301954 0.011422616 0.081506939 2.84E-05 4.546206368 0.417662751 CNTLISLIEK ddPTM_HeLa_Curcumin_4h_R1 1 CNTLISLIEK 10 0 A0A0A0MRP6;B7ZLQ5;P28370-2;P28370 A0A0A0MRP6 SMARCA1 Probable global transcription activator SNF2L1 0 0 91.318 0.019793 1358100 523.78 379.93 510.01 450.14 465.92 573.95 377.94 506.65 605.71 506.82 FALSE FALSE TRUE 482.3222603 412.7694563 528.9114193 448.27744 460.3642083 454.9063003 388.5439792 661.1252527 539.2651284 524.4319573 0.919704174 0.787079144 1.00854155 0.854786658 0.877834011 0.867426735 0.740885398 1.260650202 1.028284262 1 9.034611791 -8.69795438 0.9095024 0.993894275 0.904309118 0.069275208 0.135903304 1.10783979 1.835083671 0.054057404 0.025104356 2.00E-09 8.69795438 -0.089585157 CPFPAGAALACCS(ph)EDEEDDEEHEGGGSR ddPTM_HeLa_Curcumin_4h_R1 3 CPFPAGAALACCSEDEEDDEEHEGGGSR 28 0 Q147X3 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 0 CPFPAGAALACCS(1)EDEEDDEEHEGGGSR;CPFPAGAALACCS(1)EDEEDDEEHEGGGSR;CPFPAGAALACCS(1)EDEEDDEEHEGGGSR ;; 150.48 6.89E-11 57738600 8949.4 8175.4 8714.1 7891.8 9058.4 10643.1 5613.62 2898.76 9016.6 7136.2 TRUE FALSE FALSE 8241.045547 8882.045147 9037.052212 7859.145823 8950.384496 8435.601088 5771.123069 3782.57858 8027.501538 7384.182419 1.116040352 1.202847471 1.223839242 1.064321732 1.2121023 1.14238796 0.781552072 0.512254217 1.087121239 1 12.85022248 -4.539406807 2.943996538 1.095113468 0.527945834 0.87116747 0.076612766 0.087011908 1.406665227 0.013394243 0.085253974 2.89E-05 4.539406807 -0.567167634 CPNLTHLNLSGNK ddPTM_HeLa_Curcumin_4h_R1 1 CPNLTHLNLSGNK 13 0 P39687;H0YN26 P39687 ANP32A Acidic leucine-rich nuclear phosphoprotein 32 family member A 0 0 91.093 0.005038 2006800 1484.4 1462.8 1451.5 1378.1 1355.4 2403.2 1491.4 1424.3 2037.1 1787.8 FALSE FALSE TRUE 1366.908174 1589.237914 1505.293867 1372.397787 1339.23774 1904.74923 1533.24467 1858.562513 1813.635227 1849.925917 0.738898872 0.859081923 0.813704945 0.74186635 0.723941282 1.02963541 0.828814093 1.004668617 0.980382625 1 10.85325178 CPSPT(ph)MSLPSSWK ddPTM_HeLa_Curcumin_4h_R1 2 CPSPTMSLPSSWK 13 0 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 0 CPS(0.198)PT(0.8)MS(0.002)LPSSWK;CPS(0.36)PT(0.621)MS(0.014)LPS(0.004)S(0.001)WK ; 142.39 0.0025745 198204000 6851.8 5501.3 6092.7 5767 6708.8 7555.7 4965.5 3774.9 6804.2 5483.1 TRUE FALSE FALSE 6309.4728 5976.807859 6318.500822 5743.137682 6628.801942 5988.56265 5104.818566 4925.849632 6057.796283 5673.637317 1.112068405 1.053434953 1.113659628 1.012249702 1.168351372 1.055506779 0.899743547 0.868199597 1.067709468 1 12.47005821 -4.741921424 4.725713944 1.064179367 0.877811568 0.71506464 0.047624098 0.087038783 4.779758101 0.007717922 0.028883192 1.81E-05 4.741921424 -0.186367798 IHRAS(ph)DPGLPAEEPKEK ddPTM_HeLa_Curcumin_4h_R1 2 IHRASDPGLPAEEPKEK 17 2 P27708;F8VPD4 P27708 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 0 IHRAS(1)DPGLPAEEPKEK;IHRAS(1)DPGLPAEEPKEK ; 77.668 0.0032121 275790000 19095.5 16806.1 16254.2 20336.2 15210.3 17027.6 10187.8 6016.8 20640.5 19211.1 TRUE FALSE FALSE 17584.07103 18258.7444 16856.59495 20252.05419 15028.92711 13495.88382 10473.64225 7851.294622 18376.28879 19878.6843 0.884569158 0.918508696 0.847973372 1.018782425 0.756032285 0.678912327 0.526878041 0.394960477 0.924421784 1 14.27893465 -4.849632054 0.877862941 0.942906855 0.305422932 0.912652137 0.057752923 0.235452209 0.223775711 0.010266835 0.118230348 1.41E-05 4.849632054 -0.637483923 down CQEVISWLDANTLAEKDEFEHK ddPTM_HeLa_Curcumin_4h_R1 2 CQEVISWLDANTLAEKDEFEHK 22 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 0 ; ; 130.89 7.64E-06 97237000 7045 5414.5 5423.8 6084.8 5848.1 7869.4 5869.7 5618.3 7288.1 5741.2 FALSE FALSE TRUE 6487.380816 5882.505253 5624.810799 6059.62271 5778.365227 6237.197734 6034.387985 7331.293807 6488.613664 5940.706273 1.09202181 0.990203013 0.946825266 1.020017222 0.972673107 1.049908453 1.015769457 1.234077813 1.092229335 1 12.53641874 -4.259532149 24.80709174 1.027036818 1.234077891 0.66401933 0.045441698 79.76449001 1037393.197 0.006889474 0.059941348 5.50E-05 4.259532149 0.207041073 CQSVS(ph)SAGELETENYER ddPTM_HeLa_Curcumin_4h_R1 1 CQSVSSAGELETENYER 17 0 Q96RS0 Q96RS0 TGS1 Trimethylguanosine synthase 1 0 CQS(0.006)VS(0.497)S(0.497)AGELETENYER 218.36 1.31E-15 19898000 1217.5 976.39 967.57 983.7 1276.8 1297.9 896.27 424.6 901.12 1049.5 TRUE FALSE FALSE 1121.13359 1060.784801 1003.428995 979.62971 1261.574994 1028.70091 921.416924 554.0585854 802.2693905 1085.970047 1.032379846 0.976808526 0.923993252 0.90207802 1.161703306 0.947264533 0.848473608 0.510196931 0.738758304 1 10.0847686 -4.265159106 1.794269041 1.006007816 0.34797823 0.590566794 0.10805148 0.247218955 0.790421942 0.009457423 0.27415522 5.43E-05 4.265159106 -0.658029587 CQTAEADS(ph)ES(ph)DHEVPEPESEMK ddPTM_HeLa_Curcumin_4h_R1 2 CQTAEADSESDHEVPEPESEMK 22 0 Q9BPX3 Q9BPX3 NCAPG Condensin complex subunit 3 2 0 CQT(0.027)AEADS(0.973)ES(1)DHEVPEPESEMK;CQT(0.015)AEADS(0.986)ES(0.998)DHEVPEPES(0.001)EMK ; 91.691 0.00062857 56616000 6102.4 5395.5 4668.8 5233.5 5529.4 5833 4889.2 3526.8 6437.9 5613.8 TRUE FALSE FALSE 5619.388601 5861.862978 4841.829835 5211.845164 5463.465516 4623.170049 5026.377793 4602.105085 5731.678477 5808.879132 0.967379157 1.009121182 0.833522221 0.897220453 0.940536959 0.795879884 0.865292198 0.792253545 0.986709888 1 12.5040441 -5.656869691 0.368151555 1.000760256 0.764527121 0.658786085 0.046334209 1.038707977 0.200106878 0.017419529 0.096558346 2.20E-06 5.656869691 -0.236233135 CQTAEADS(ph)ESDHEVPEPESEMK ddPTM_HeLa_Curcumin_4h_R1 1 CQTAEADSESDHEVPEPESEMK 22 0 Q9BPX3 Q9BPX3 NCAPG Condensin complex subunit 3 1 0 CQT(0.019)AEADS(0.594)ES(0.387)DHEVPEPESEMK 93.546 0.00011969 11841000 6148.4 4647.4 4957.2 5333.6 5805.1 6156.1 4956.7 13135 5726.2 5788.6 TRUE FALSE FALSE 5661.747652 5049.100548 5140.918193 5311.530976 5735.877974 4879.255466 5095.771662 17139.80103 5098.050186 5989.753419 0.945238853 0.842956328 0.858285447 0.886769555 0.957615042 0.814600389 0.850748154 2.861520306 0.851128557 1 12.5482809 -4.259948027 24.99999901 0.9334575 2.861520937 0.986146083 0.069940935 11.55211071 193632.4156 0.010957919 0.092529698 5.50E-05 4.259948027 1.928063438 CQVFEETQIGGER ddPTM_HeLa_Curcumin_4h_R1 2 CQVFEETQIGGER 13 0 Q99832-3;Q99832;Q99832-2;Q99832-4 Q99832-3 CCT7 T-complex protein 1 subunit eta 0 0 ; ; 210.95 3.84E-20 5641800 1380.73 1069.84 1323.21 1187.46 1102.05 1250.59 1257.6 864.71 1349.22 1115.24 FALSE FALSE TRUE 1271.443764 1162.312202 1372.249327 1182.546605 1088.908774 991.2035369 1292.884871 1128.356098 1201.213942 1153.994507 1.10177627 1.007207743 1.18912986 1.024741971 0.943599616 0.85893263 1.120356175 0.977782902 1.040918249 1 10.17242064 -5.993300819 22.99691241 1.057436192 0.978102713 0.232629626 0.078123007 86.40233003 296591.8091 0.011911302 0.021541777 1.02E-06 5.993300819 -0.079333478 CQYVTEK ddPTM_HeLa_Curcumin_4h_R1 1 CQYVTEK 7 0 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;P09972 P04075;P09972 ALDOA;ALDOC Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase;Fructose-bisphosphate aldolase C 0 0 130.27 0.0078837 18463000 3491.1 2993 3455.5 2979.5 3342.1 3640.8 2802 2589.6 3318.9 2621.7 FALSE FALSE TRUE 3214.775751 3251.701583 3583.56387 2967.171618 3302.24764 2885.65704 2880.616579 3379.157119 2954.824973 2712.80388 1.185038025 1.19864971 1.320981548 1.09376562 1.217282113 1.063717529 1.061859503 1.245632662 1.089214372 1 11.40556904 -9.156154905 0.915822184 1.000353169 1.170172428 0.258267731 0.082163861 0.465412773 0.705845513 0.051686278 0.014973292 6.98E-10 9.156154905 0.169819259 CS(ph)ELS(ph)CMLQTVTMEK ddPTM_HeLa_Curcumin_4h_R1 1 CSELSCMLQTVTMEK 15 0 Q8NCX0 Q8NCX0 CCDC150 Coiled-coil domain-containing protein 150 2 0 CS(1)ELS(0.997)CMLQT(0.002)VT(0.001)MEK 77.527 0.0055018 4888800 299.42 329.05 277 372.45 241.65 481.69 236.23 259.57 250.07 460.89 TRUE FALSE FALSE 275.7205911 357.4916158 287.2658637 370.9089006 238.7684816 381.7820642 242.857978 338.7116981 222.6379466 476.9058932 0.578144651 0.749606203 0.602353353 0.777740233 0.500661629 0.800539624 0.509236689 0.710227537 0.466838321 1 8.8975608 -9.355008238 0.875907974 1.019725271 0.648190648 0 0.193451726 0.31482978 0.39462965 0.080944722 0.017140846 4.42E-10 9.355008238 -0.371534623 CS(ph)GPGLPLY(ph)TLHS(ph)SVNDK ddPTM_HeLa_Curcumin_4h_R1 1 CSGPGLPLYTLHSSVNDK 18 0 P27487 P27487 DPP4 Dipeptidyl peptidase 4;Dipeptidyl peptidase 4 membrane form;Dipeptidyl peptidase 4 soluble form 3 0 CS(1)GPGLPLY(0.934)T(0.129)LHS(0.469)S(0.469)VNDK 46.156 0.0095183 0 915.47 786.09 860.25 771.56 907.39 1204.1 1102 565.6 962.72 899.97 TRUE FALSE FALSE 843.0095835 854.0361169 892.1316218 768.3674892 896.5699669 954.356087 1132.919154 738.0488363 857.1120246 931.2438905 0.905251129 0.91709178 0.957999973 0.825098019 0.962766012 1.024818629 1.216565462 0.792540863 0.92039479 1 9.863015245 -5.302284835 4.860120125 0.941622844 1.032206013 0.100239353 0.105493442 0.304095737 17.49415124 0.01421487 0.0334919 4.99E-06 5.302284835 0.090583169 CS(ph)LPAEEDSVLEK ddPTM_HeLa_Curcumin_4h_R1 1 CSLPAEEDSVLEK 13 0 E7EVA0;P27816;P27816-6 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 CS(1)LPAEEDSVLEK 116.9 0.0027926 6248000 3417.6 2668.9 2924.7 2864.9 2803.3 2986.6 2437.6 1239.9 3361.2 2647.7 TRUE FALSE FALSE 3147.093354 2899.587824 3033.091955 2853.045803 2769.872478 2367.145494 2505.992496 1617.939802 2992.484769 2739.707378 1.148696893 1.05835676 1.1070861 1.041368807 1.011010337 0.864013987 0.914693487 0.590552048 1.092264376 1 11.4198061 -3.789409311 0.709309065 1.073126867 1.19E-13 0.874818292 0.054559004 1.488186309 0.331596128 0.011133515 1.493019541 0.000162402 3.789409311 -1.073126867 ELS(ph)QNTDESGLNDEAIAK ddPTM_HeLa_Curcumin_4h_R1 1 ELSQNTDESGLNDEAIAK 18 0 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 0 ELS(0.962)QNT(0.011)DES(0.026)GLNDEAIAK 138.97 0.00031115 6068400 967.45 466.68 705.42 803.31 654.87 994.09 1043.5 1169.8 975.12 623.05 TRUE FALSE FALSE 890.8753117 507.0177397 731.5634858 799.9861161 647.061103 787.9045283 1072.777802 1526.466635 868.1517756 644.7009411 1.381842735 0.786438653 1.134733082 1.240863887 1.003660863 1.222124055 1.66399292 2.367712745 1.346596104 1 9.332486279 -4.381356869 1.834960976 1.142711036 2.594227245 0.841374373 0.166974048 0.201584067 0.827054391 0.02627008 0.460511662 4.16E-05 4.381356869 1.451516208 up CSATPSAQVKPIVS(ph)ASPPSR ddPTM_HeLa_Curcumin_4h_R1 2 CSATPSAQVKPIVSASPPSR 20 1 Q96EV2;H0Y3K4 Q96EV2 RBM33 RNA-binding protein 33 1 0 CSATPSAQVKPIVS(0.801)AS(0.186)PPS(0.013)R;CSATPSAQVKPIVS(0.583)AS(0.404)PPS(0.013)R ; 102.21 0.00018805 120799000 4858 3015.3 3574.2 3165.2 3534.5 4152.3 3133.4 2064.7 3942.2 3377.5 TRUE FALSE FALSE 4473.484174 3275.929096 3706.662996 3152.103241 3492.353396 3291.066174 3221.314771 2694.217525 3509.750523 3494.867874 1.28001525 0.937354205 1.060601754 0.901923436 0.999280523 0.941685435 0.921727198 0.770906833 1.00425843 1 11.7710222 -6.66178118 1.484156436 1.127473004 0.913628694 0.284495358 0.10508369 0.312102799 1.390895793 0.021759636 0.033531563 2.18E-07 6.66178118 -0.213844309 CSFMDVNSNS(ph)HAEPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 CSFMDVNSNSHAEPSR 16 0 Q5T5P2;Q5T5P2-3;Q5T5P2-7;Q5T5P2-8;Q5T5P2-6;Q5T5P2-10;A0A0U1RRK8 Q5T5P2 KIAA1217 Sickle tail protein homolog 2 0 CSFMDVNSNS(1)HAEPS(1)R 76.228 0.02008 34046000 1884.9 1874.4 1959.2 2079 2045.4 2527.9 1562.5 1352.4 2251.5 1920.2 TRUE FALSE FALSE 1735.708176 2036.414784 2031.809675 2070.397649 2021.009941 2003.585045 1606.339545 1764.740534 2004.516083 1986.926807 0.873564225 1.024906794 1.02258909 1.042010023 1.017153694 1.008383921 0.808454312 0.888175915 1.008852503 1 10.95632301 -4.761119812 24.99977853 0.967427612 0.8483151 0.478971711 0.055519716 7.335043689 573546.7494 0.009908192 0.033007463 1.73E-05 4.761119812 -0.119112513 CSGPGLS(ph)PGMVR ddPTM_HeLa_Curcumin_4h_R1 1 CSGPGLSPGMVR 12 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 CSGPGLS(1)PGMVR 157.5 0.00028733 653360000 4411.1 3061.8 3137.8 3175.7 3915.7 3709.7 3291 2833.4 3234.1 3444.8 TRUE FALSE FALSE 4061.95678 3326.448349 3254.089628 3162.559795 3869.007835 2940.266403 3383.336603 3697.290617 2879.327321 3564.506544 1.13955655 0.933214264 0.912914477 0.887236355 1.085425931 0.824873336 0.949173907 1.037251741 0.807777258 1 11.79948665 -7.241065263 24.26928667 1.065901705 0.944226683 0 0.111178468 484.9260655 577635.771 0.01357402 0.016613499 5.74E-08 7.241065263 -0.121675022 CSGPGLSPGMVR ddPTM_HeLa_Curcumin_4h_R1 2 CSGPGLSPGMVR 12 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 149.72 5.16E-05 7399300 2246.6 1761.75 1907.51 2036.92 2143.77 2552.3 2168.4 1998.63 2226.7 1780.22 FALSE FALSE TRUE 2068.779239 1914.02782 1978.203999 2028.491765 2118.206943 2022.92421 2229.239468 2608.003086 1982.436581 1842.082512 1.123065457 1.039056506 1.073895434 1.101194844 1.149897971 1.098172419 1.210173514 1.41579059 1.07619315 1 10.84712197 -1 0.596837829 1.059133812 22.73439038 0.886700484 0.037115946 44.99810918 0.32414228 0.008779636 1274.704761 0.1 1 21.67525656 CSK(ac)LPSSTK ddPTM_HeLa_Curcumin_4h_R1 2 CSKLPSSTK 9 1 D6R9B8;C9J929;B5MBX1;A0A0C4DFT8;G3XAA4;Q9NQC1-3;Q9NQC1-2;Q9NQC1 D6R9B8 JADE2 Protein Jade-2 0 1 ; CSK(1)LPSSTK;CSK(1)LPSSTK 115.57 0.0017707 11195200 7722.1 4981.6 6591.8 5807.1 6949.7 7374 5088.6 2893.3 6090.1 6052.3 FALSE TRUE FALSE 7110.887637 5412.187306 6836.097907 5783.071759 6866.829366 5844.549278 5231.372421 3775.453851 5422.031267 6262.616975 1.135449871 0.864205384 1.091572091 0.923427344 1.096479219 0.93324393 0.835333287 0.602855622 0.865777244 1 12.61254993 -3.844110144 0.843762954 1.047452767 1.03E-14 0.56440556 0.099040995 1.618240772 0.523201309 0.013304675 1.858873125 0.000143182 3.844110144 -1.047452767 CSK(ac)LPSSTK(ac)SGWPR ddPTM_HeLa_Curcumin_4h_R1 2 CSKLPSSTKSGWPR 14 2 D6R9B8;C9J929;B5MBX1;A0A0C4DFT8;G3XAA4;Q9NQC1-3;Q9NQC1-2;Q9NQC1 D6R9B8 JADE2 Protein Jade-2 0 2 ; CSK(1)LPSSTK(1)SGWPR;CSK(1)LPSSTK(1)SGWPR 249.28 2.32E-61 61032000 4830.4 4055.8 4096 3753.8 4455.2 5809 4097 2126.4 5025.4 3865.1 FALSE TRUE FALSE 4448.068743 4406.36528 4247.801363 3738.26777 4402.07465 4604.147919 4211.950793 2774.729571 4474.126193 3999.411937 1.112180694 1.101753295 1.062106487 0.934704359 1.10068048 1.151206225 1.053142527 0.69378439 1.118696014 1 11.96557217 -4.26207844 7.164903554 1.059844278 0.688945742 0.772978729 0.061011031 0.040198101 16.99564227 0.009010342 0.07230194 5.47E-05 4.26207844 -0.370898536 SAYLPGQT(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 SAYLPGQTSPK 11 0 H0YJ41;Q9P203-5;Q9P203 H0YJ41 BTBD7 BTB/POZ domain-containing protein 7 1 0 SAYLPGQT(0.5)S(0.5)PK 110.64 0.018783 22827000 3337 2905.3 3073.2 2853.9 2415 2929.6 1823.3 1071.8 3572.2 2791.5 TRUE FALSE FALSE 3072.872929 3156.421186 3187.095495 2842.091318 2386.202702 2321.967937 1874.456891 1398.586886 3180.338597 2888.504417 1.063828364 1.092752764 1.103372208 0.983931789 0.826103186 0.803865115 0.648936827 0.484190669 1.10103297 1 11.49610699 -4.849003419 0.842872086 1.042128866 0.40828405 0.938147524 0.050497965 0.220597938 0.188712094 0.008963013 0.107201626 1.42E-05 4.849003419 -0.633844816 down CSPTVAFVEFPSS(ph)PQLK ddPTM_HeLa_Curcumin_4h_R1 3 CSPTVAFVEFPSSPQLK 17 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 CSPTVAFVEFPS(0.048)S(0.952)PQLK;CSPTVAFVEFPS(0.206)S(0.794)PQLK;CSPTVAFVEFPS(0.337)S(0.663)PQLK ;; 218.2 1.34E-15 123785100 8292.4 7134.9 6905.29 7009.9 8308.3 9100.3 6557.8 3629.4 6840.11 5707.07 TRUE FALSE FALSE 7636.04779 7751.608964 7161.206122 6980.894891 8209.228949 7212.795198 6741.794219 4735.987352 6089.767046 5905.390258 1.293064041 1.312632802 1.212655863 1.182122533 1.390124715 1.221391794 1.141633986 0.801977032 1.031221779 1 12.52781669 -4.266132745 3.844935012 1.18444946 0.765999264 0.520530736 0.114131509 0.194853621 5.65089139 0.01947982 0.227560626 5.42E-05 4.266132745 -0.418450196 CSQAVYAAEK ddPTM_HeLa_Curcumin_4h_R1 2 CSQAVYAAEK 10 0 E9PP21;P21291;E9PND2;E9PS42 E9PP21 CSRP1 Cysteine and glycine-rich protein 1 0 0 ; ; 133.07 0.0010359 3695200 3040.7 2112 2507.7 2502 2780.8 2716.9 2090.83 1885.35 2458.71 2711 FALSE FALSE TRUE 2800.025386 2294.551869 2600.637568 2491.647387 2747.640776 2153.384314 2149.493063 2460.184536 2188.995664 2805.207048 0.998152842 0.81796168 0.927075087 0.888222275 0.97947878 0.76763828 0.766251127 0.8770064 0.780333012 1 11.45389154 -6.275598692 0.412183823 1.011491472 0.789746476 0 0.097069331 0.829018078 0.269784858 0.025080911 0.074320615 5.30E-07 6.275598692 -0.221744996 CSSSS(ph)GGGSSGDEDGLELDGAPGGGKR ddPTM_HeLa_Curcumin_4h_R1 1 CSSSSGGGSSGDEDGLELDGAPGGGKR 27 1 Q9P258 Q9P258 RCC2 Protein RCC2 1 0 CS(0.037)S(0.109)S(0.109)S(0.333)GGGS(0.239)S(0.173)GDEDGLELDGAPGGGKR 75.301 9.44E-05 39041000 3593.4 2807 3189.7 4142.2 3046.9 4799.4 3795.2 1329.4 4156.9 2890.3 TRUE FALSE FALSE 3308.978598 3049.624572 3307.913088 4125.060674 3010.567707 3803.95034 3901.683098 1734.72794 3700.89847 2990.73771 1.106408826 1.019689745 1.106052556 1.379278651 1.00663047 1.271910381 1.304588859 0.580033459 1.237453374 1 11.54628568 -8.886782509 0.619738204 0.995147526 1.117747645 0 0.221658418 2.600238764 1.775139116 0.166589121 0.046772418 1.30E-09 8.886782509 0.122600119 CSSSSGGGS(ph)S(ph)GDEDGLELDGAPGGGKR ddPTM_HeLa_Curcumin_4h_R1 2 CSSSSGGGSSGDEDGLELDGAPGGGKR 27 1 Q9P258 Q9P258 RCC2 Protein RCC2 2 0 CS(0.015)S(0.013)S(0.138)S(0.303)GGGS(0.748)S(0.783)GDEDGLELDGAPGGGKR;CS(0.014)S(0.038)S(0.039)S(0.135)GGGS(0.876)S(0.897)GDEDGLELDGAPGGGKR ; 103.25 5.66E-08 21440000 8868.1 6752.4 6642.6 6534.2 6983.6 8822.9 6384.1 5260.4 8282 6997.6 TRUE FALSE FALSE 8166.180527 7336.047368 6888.780599 6507.163212 6900.325131 6992.931085 6563.220664 6864.271744 7373.485321 7240.766079 1.127806152 1.013159007 0.951388365 0.898684358 0.952982745 0.965772269 0.90642628 0.948003522 1.018329447 1 12.82192663 -6.859895102 3.34627977 1.060680215 0.935298799 0.646980035 0.037382194 0.129932068 2.890732649 0.008297412 0.011197721 1.38E-07 6.859895102 -0.125381416 CSSSSGGGS(ph)SGDEDGLELDGAPGGGKR ddPTM_HeLa_Curcumin_4h_R1 1 CSSSSGGGSSGDEDGLELDGAPGGGKR 27 1 Q9P258 Q9P258 RCC2 Protein RCC2 1 0 CSSSS(0.001)GGGS(0.499)S(0.499)GDEDGLELDGAPGGGKR 163.09 1.73E-19 0 2252.1 1806.9 1889.3 2387 1780.1 3018.1 1628.6 772.94 2494 1504.3 TRUE FALSE FALSE 2073.843909 1963.080385 1959.31912 2377.123226 1758.87347 2392.112039 1674.294133 1008.605848 2220.41444 1556.574313 1.332312817 1.261154298 1.258737924 1.527150491 1.129964342 1.53677985 1.075627497 0.647965111 1.426475062 1 10.60415874 -4.323115681 3.757302586 1.221651558 0.620520565 0.526376728 0.176494684 0.15809568 3.8826807 0.026483182 0.230117232 4.75E-05 4.323115681 -0.601130993 MPLPS(ph)PTESR ddPTM_HeLa_Curcumin_4h_R1 1 MPLPSPTESR 10 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 0 MPLPS(0.962)PT(0.038)ESR 132.03 0.0026329 13150000 2843.2 2394.8 2370.7 2225.6 2292.4 2189.1 1046.2 588.81 2589.9 2222.5 TRUE FALSE FALSE 2618.15772 2601.795841 2458.560227 2216.391057 2265.064627 1735.055984 1075.553556 768.3354585 2305.79445 2299.73171 1.138462243 1.131347552 1.069063934 0.963760706 0.984925597 0.754460173 0.467686536 0.334097867 1.002636281 1 11.16724985 -4.847826244 1.136504909 1.070373074 0.247373416 0.963803091 0.050219515 0.110570352 0.205856424 0.009473389 0.084300406 1.42E-05 4.847826244 -0.822999658 down CSVS(ph)LSNVEAR ddPTM_HeLa_Curcumin_4h_R1 2 CSVSLSNVEAR 11 0 P47712 P47712 PLA2G4A Cytosolic phospholipase A2;Phospholipase A2;Lysophospholipase 1 0 CS(0.004)VS(0.958)LS(0.038)NVEAR;CS(0.011)VS(0.985)LS(0.003)NVEAR ; 127.78 0.0031776 22917000 2305.7 1684.24 2306.67 2133.3 1520.76 2030 1346.47 1191.44 2034.98 3062.2 TRUE FALSE FALSE 2123.201412 1829.818201 2392.157219 2124.47297 1502.62593 1608.955117 1384.248324 1554.704571 1811.747785 3168.611222 0.670073185 0.577482712 0.754954474 0.670474483 0.474222246 0.507779278 0.436862785 0.49065804 0.571779767 1 11.62963494 -13.52287875 0.08924455 2.535829654 0.162745679 0.133402159 0.1488601 34.36848585 0.232547894 10.04672678 0.87611115 3.00E-14 13.52287875 -2.373083975 CTGGEVGATSALAPK ddPTM_HeLa_Curcumin_4h_R1 2 CTGGEVGATSALAPK 15 0 P30050;P30050-2 P30050 RPL12 60S ribosomal protein L12 0 0 ; ; 204.48 1.97E-18 12329200 5390.8 4794 4886.8 5209.5 4991.2 6144.2 5060.3 4719 5274.1 4460.5 FALSE FALSE TRUE 4964.112492 5208.371998 5067.909107 5187.944469 4931.6832 4869.823661 5202.278399 6157.801376 4695.544425 4615.502043 1.075530342 1.128451889 1.098019037 1.124026037 1.068504174 1.055101615 1.127131643 1.334156354 1.017342075 1 12.17227187 CTKEEHLCTQR ddPTM_HeLa_Curcumin_4h_R1 1 CTKEEHLCTQR 11 1 A0A087WWU8;P06753-2;P06753-5;P06753-7;J3KN67 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 0 60.255 0.016634 3294500 6638.5 5211.3 5547.5 4838.8 5180.3 6647.4 4833.9 3881.8 6987.2 5825.8 FALSE FALSE TRUE 6113.05572 5661.741551 5753.09523 4818.778328 5118.528306 5268.654308 4969.526224 5065.34295 6220.721641 6028.246116 1.014068703 0.939202123 0.954356395 0.799366554 0.849090798 0.873994559 0.824373479 0.840268107 1.031928943 1 12.5575226 -6.601336289 1.631482673 1.005470253 0.839160779 0.868189959 0.029491883 0.080519423 0.432870866 0.004522324 0.007070033 2.50E-07 6.601336289 -0.166309474 CTLPEHES(ph)PSQDISDACEAESTER ddPTM_HeLa_Curcumin_4h_R1 4 CTLPEHESPSQDISDACEAESTER 24 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 0 CTLPEHES(0.974)PS(0.025)QDIS(0.001)DACEAESTER;CTLPEHES(1)PSQDISDACEAESTER;CTLPEHES(0.997)PS(0.003)QDISDACEAESTER;CTLPEHES(0.935)PS(0.065)QDISDACEAESTER ;;; 150.63 1.99E-07 186556000 7373.2 6306.2 7221.4 6327.3 7680.4 7947.9 5213.35 3913.56 6829.6 5832.2 TRUE FALSE FALSE 6789.60344 6851.279828 7489.031437 6301.119309 7588.816246 6299.415949 5359.62257 5106.786428 6080.409967 6034.868516 1.125062364 1.135282369 1.240960166 1.04411874 1.257494878 1.043836487 0.888109253 0.846213371 1.007546387 1 12.55910662 -4.780973223 3.779753776 1.09226641 0.85824866 0.566410978 0.084262755 0.132942579 4.029407089 0.012851668 0.048239075 1.66E-05 4.780973223 -0.23401775 CTVS(ph)EMALDS(ph)PFCVLLSGS(ph) ddPTM_HeLa_Curcumin_4h_R1 1 CTVSEMALDSPFCVLLSGS 19 0 Q5SRD1-2;Q5SRD1 Q5SRD1-2 TIMM23B Putative mitochondrial import inner membrane translocase subunit Tim23B 3 0 CT(0.161)VS(0.839)EMALDS(0.934)PFCVLLS(0.296)GS(0.769) 45.972 0.017164 3604800 1790.2 1565.7 1595.7 1741.2 1880.4 884.59 790.26 959.64 1914.3 1499.6 TRUE FALSE FALSE 1648.503781 1701.032131 1654.838046 1733.995376 1857.977458 701.1160626 812.4325687 1252.229818 1704.306079 1551.710988 1.062378106 1.096229997 1.066460222 1.117473156 1.197373398 0.45183418 0.523572092 0.806999388 1.098339892 1 10.59964416 -5.260874566 24.99960806 1.054530379 0.587078896 0.833280167 0.100941007 14.99438292 663655.3987 0.014241554 0.034049096 5.48E-06 5.260874566 -0.467451483 CVACQNPDKPSPS(ph)TSVPAPASFK ddPTM_HeLa_Curcumin_4h_R1 2 CVACQNPDKPSPSTSVPAPASFK 23 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 CVACQNPDKPS(0.36)PS(0.552)T(0.065)S(0.023)VPAPASFK;CVACQNPDKPS(0.332)PS(0.499)T(0.133)S(0.036)VPAPASFK ; 93.804 6.15E-05 58551000 4514.3 3628.1 3968.4 4633.8 4419.8 5478 4407.3 5021.3 4892 4125.9 TRUE FALSE FALSE 4156.988392 3941.696798 4115.472395 4614.626563 4367.096772 4341.80105 4530.956976 6552.271255 4355.359839 4269.274718 0.973698969 0.923270827 0.963974602 1.080892392 1.022913038 1.016987975 1.061294312 1.534750441 1.020163875 1 12.05977528 -4.224070283 2.722737232 0.9919069 1.669833218 0.939219782 0.040480183 0.09024542 0.816268173 0.005895344 0.142538274 5.97E-05 4.224070283 0.677926318 CVMDDDNEVRDR ddPTM_HeLa_Curcumin_4h_R1 1 CVMDDDNEVRDR 12 1 Q9Y678 Q9Y678 COPG1 Coatomer subunit gamma-1 0 0 124.42 0.017492 9166200 2170.8 2067.6 2430.8 2235 1943.6 2478.4 1681.6 1693.7 2477.6 2428.3 FALSE FALSE TRUE 1998.978889 2246.314131 2520.887586 2225.752162 1920.423839 1964.351903 1728.78117 2210.101333 2205.813479 2512.683244 0.795555466 0.893990174 1.003265172 0.885806903 0.764292055 0.781774586 0.688021928 0.879578171 0.877871687 1 11.2950131 -5.810748559 5.130789536 0.908288959 0.771887829 0.451400774 0.070876296 0.172135286 9.842531491 0.013328185 0.024954413 1.55E-06 5.810748559 -0.136401131 CVWS(ph)PLASPSTSILK ddPTM_HeLa_Curcumin_4h_R1 1 CVWSPLASPSTSILK 15 0 Q5UIP0-2;Q5UIP0;H7C2B5 Q5UIP0-2 RIF1 Telomere-associated protein RIF1 1 0 CVWS(0.996)PLAS(0.003)PS(0.001)TSILK 122.33 0.0011482 4954600 895.44 687.83 658.27 1012.2 939.13 1083.7 658.87 339.83 1026.3 923.97 TRUE FALSE FALSE 824.5649791 747.2829603 682.6660653 1008.011785 927.9314881 858.9284042 677.3561189 443.4426026 913.7174577 956.0778887 0.862445402 0.781613056 0.714027668 1.054319733 0.970560557 0.898387479 0.708473783 0.463814306 0.955693535 1 9.900984345 -4.44568653 2.08028369 0.917013465 0.42152692 0.671326394 0.096607716 0.230914481 1.436700275 0.015308268 0.184830695 3.58E-05 4.44568653 -0.495486545 CYEMAS(ph)HLR ddPTM_HeLa_Curcumin_4h_R1 1 CYEMASHLR 9 0 P07737;K7EJ44;CON__P02584 P07737 PFN1 Profilin-1 1 0 CYEMAS(1)HLR 78.903 0.0074724 0 1844.4 1632 1824.5 1945.2 2075.5 2656.7 1866.4 1537.7 1976.2 1804.8 TRUE FALSE FALSE 1698.413794 1773.062808 1892.117575 1937.151278 2050.751018 2105.670473 1918.766161 2006.537651 1759.415804 1867.516666 0.909450408 0.94942275 1.01317306 1.037287277 1.098116582 1.127524328 1.027442591 1.074441631 0.942115182 1 10.8669054 -6.351402156 1.913761808 0.955760593 1.079336332 0.757994662 0.032872742 0.159090045 1.139891419 0.006842135 0.011603469 4.45E-07 6.351402156 0.123575739 CYEMASHLR ddPTM_HeLa_Curcumin_4h_R1 1 CYEMASHLR 9 0 P07737;K7EJ44;CON__P02584 P07737 PFN1 Profilin-1 0 0 107.21 0.0012876 5323700 4418.7 2843.4 3620.9 3145.7 3925.1 5324.9 3887.6 3455.8 3612.5 3646.7 FALSE FALSE TRUE 4068.955232 3089.170826 3755.093739 3132.683927 3878.295746 4220.455716 3996.675593 4509.457511 3216.217788 3773.422554 1.078319529 0.818665491 0.995142655 0.830196958 1.027792592 1.118468885 1.059164601 1.195057656 0.852334384 1 11.88165795 -5.315586719 4.693862605 1.000783011 1.118292656 0.314791556 0.100010421 0.238272687 11.33596761 0.013826356 0.032440426 4.84E-06 5.315586719 0.117509646 DAAEARVAELPAACEEAR ddPTM_HeLa_Curcumin_4h_R1 1 DAAEARVAELPAACEEAR 18 1 Q8TF21;Q8TF21-2 Q8TF21 ANKRD24 Ankyrin repeat domain-containing protein 24 0 0 41.554 0.0169 7410400 720.33 654.75 874.67 854.7 1066.9 565.83 913.93 616.36 669.66 714.08 FALSE FALSE TRUE 663.3151204 711.3436725 907.0860396 851.1634779 1054.177914 448.4704798 939.5724161 804.2853266 596.1999734 738.8942268 0.897713226 0.962713805 1.227626373 1.15194225 1.426696645 0.606948144 1.27159258 1.088498593 0.806881353 1 9.529224046 -6.844102047 8.643365709 0.950774256 1.126065947 0.197651558 0.204806813 0.380305171 35.78392916 0.030477225 0.04010974 1.43E-07 6.844102047 0.17529169 DAALATALGDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 DAALATALGDKK 12 1 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 0 1 DAALATALGDK(1)K 103.21 0.0020501 1452500 1911.8 1563.6 1758.5 1948.3 2222.3 2785.5 2051.6 2089.6 2472.4 2132.5 FALSE TRUE FALSE 1760.479013 1698.750617 1823.671557 1940.238451 2195.800524 2207.755901 2109.162374 2726.709421 2201.183906 2206.604216 0.797822736 0.769848351 0.826460651 0.879287022 0.995103928 1.000521926 0.955840816 1.235703893 0.997543596 1 11.10761217 -1.000000108 0.726157095 0.888357563 51.27393924 0.601015587 0.081555952 193.2527777 0.862736284 0.016076435 15894.39398 0.099999975 1.000000108 50.38558167 DAASVDKVLELK ddPTM_HeLa_Curcumin_4h_R1 1 DAASVDKVLELK 12 1 O14979-3;O14979-2;A0A087WUK2;O14979 O14979-3 HNRNPDL Heterogeneous nuclear ribonucleoprotein D-like 0 0 80.834 0.0081031 0 642.91 601.46 585.91 879.85 472.39 915.77 577.14 563.07 1061.6 817.04 FALSE FALSE TRUE 592.0229951 653.4475223 607.62434 876.2094138 466.7570578 725.8289791 593.3329951 734.7474509 945.145136 845.4320792 0.70026086 0.772915458 0.718714554 1.036404266 0.552092911 0.858530208 0.701810364 0.869079219 1.117943309 1 9.723545045 -9.397668453 1.072314571 1.002672997 0.769693369 0.415383479 0.128584743 0.454166509 0.91706516 0.081025609 0.01973339 4.00E-10 9.397668453 -0.232979628 DADAGDEDEESEEPR ddPTM_HeLa_Curcumin_4h_R1 2 DADAGDEDEESEEPR 15 0 Q9NZT2-2;Q9NZT2;A0A087X028 Q9NZT2-2 OGFR Opioid growth factor receptor 0 0 ; ; 369.42 2.82E-189 26973000 6566.6 5295.6 5418 6295.8 5723.6 6788.8 5217.6 3935 6621 6374.1 FALSE FALSE TRUE 6046.846681 5753.328067 5618.795846 6269.749648 5655.349808 5380.726354 5363.991814 5134.763385 5894.692865 6595.599501 0.916800161 0.872297972 0.851900702 0.95059587 0.857442877 0.815805501 0.813268273 0.77851352 0.893731171 1 12.68728808 -1 0.080685657 1.130742993 0.201915194 0.518441099 0.044386089 51.48788107 0.305343766 0.538750338 5.357175109 0.1 1 -0.928827799 DADETKEWIEEK ddPTM_HeLa_Curcumin_4h_R1 2 DADETKEWIEEK 12 1 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 ; ; 96.756 0.0095842 44225000 5015 4136.7 4626.7 4752 4440.4 6172.2 4523 4187.6 5251.6 4352.7 FALSE FALSE TRUE 4618.057458 4494.257915 4798.169572 4732.337483 4387.45113 4892.016145 4649.903207 5464.379963 4675.512619 4503.956001 1.025333608 0.997846763 1.065323367 1.050706863 0.974132769 1.086159843 1.032404226 1.213240085 1.038090207 1 12.13697702 -1.104630363 1.040921184 1.016911681 199.9999997 0.725232621 0.033234064 569.6412119 0.764607101 0.004769744 270450.947 0.078590425 1.104630363 198.983088 DADLS(ph)PVNASIIK ddPTM_HeLa_Curcumin_4h_R1 1 DADLSPVNASIIK 13 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 0 DADLS(0.998)PVNAS(0.002)IIK 167.61 0.00018617 5909200 2189 1980.2 2467.7 2254.1 2911.1 2494.9 2106.9 2407.7 1925.4 1350.7 TRUE FALSE FALSE 2015.73834 2151.359664 2559.155133 2244.773131 2876.387034 1977.429617 2166.013944 3141.796646 1714.188437 1397.636724 1.442247692 1.539283869 1.831058878 1.606120598 2.058036243 1.414838049 1.54976891 2.247935097 1.226490695 1 10.44877371 -8.122799419 0.349408714 0.895868091 1.852304929 0.542815282 0.238790975 0.696232701 0.214423777 0.269341356 0.136200947 7.54E-09 8.122799419 0.956436838 DADLS(ph)PVNASIIKENYEKDEDFLSSTR ddPTM_HeLa_Curcumin_4h_R1 1 DADLSPVNASIIKENYEKDEDFLSSTR 27 2 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 0 DADLS(0.725)PVNAS(0.254)IIKENY(0.021)EKDEDFLSSTR 43.073 0.011966 7234700 1561.2 1095.9 1195.4 1392.6 1176.4 1842.4 1292.9 1241.8 1519.1 1470.4 TRUE FALSE FALSE 1437.629373 1190.624713 1239.702576 1386.83779 1162.372198 1460.265472 1329.175294 1620.419103 1352.458531 1521.496291 0.944878658 0.782535403 0.814791717 0.911496005 0.763966502 0.959756183 0.87359746 1.065016795 0.888900314 1 10.5712751 -7.494617926 5.779571206 0.976359308 0.877215838 0.072715115 0.087903171 0.200107738 17.97622158 0.014287808 0.015768416 3.20E-08 7.494617926 -0.09914347 SLS(ph)APLHPEFEEVYR ddPTM_HeLa_Curcumin_4h_R1 1 SLSAPLHPEFEEVYR 15 0 Q53HC0-2;Q53HC0 Q53HC0-2 CCDC92 Coiled-coil domain-containing protein 92 1 0 S(0.01)LS(0.99)APLHPEFEEVYR 113.14 0.00089702 2728800 3763 3000.6 3383.3 3551.7 3667 7251.7 7660.4 8848.2 4114.7 3211.2 TRUE FALSE FALSE 3465.154579 3259.958494 3508.688074 3537.004006 3623.27342 5747.615676 7875.330207 11545.97545 3663.327704 3322.788961 1.042845218 0.981091045 1.055946711 1.064468447 1.0904314 1.729756462 2.370096416 3.474784461 1.102485818 1 11.69817895 -4.380962913 1.03923293 1.013245673 4.422111112 0.993454573 0.063445021 0.068009409 0.065381827 0.008470515 0.2435963 4.16E-05 4.380962913 3.408865439 up DADS(ph)QNPDAPEGKR ddPTM_HeLa_Curcumin_4h_R1 1 DADSQNPDAPEGKR 14 1 A0A3B3ISK1;A0A3B3ITV3;A0A3B3ISC6;A0A3B3IT15;A0A3B3IS84;P53621;P53621-2;A0A3B3IU89 A0A3B3ISK1 COPA Coatomer subunit alpha;Xenin;Proxenin 1 0 DADS(1)QNPDAPEGKR 86.222 0.006291 14004000 632.66 625.99 530.11 665.68 655.57 909.9 1013.5 15986 0 616.06 TRUE FALSE FALSE 582.5842934 680.0977862 549.7563429 662.9255925 647.7527559 721.1764833 1041.936082 20860.05781 0 637.4680391 0.913903533 1.066873544 0.862406127 1.039935419 1.016133698 1.131313947 1.634491486 32.72329988 0 1 9.316209201 -4.261328296 6.415541469 0.990803726 33.39178177 0.998863849 0.32141853 0.001001597 0.237933473 0.016707987 0.140261747 5.48E-05 4.261328296 32.40097805 DADSQNPDAPEGK ddPTM_HeLa_Curcumin_4h_R1 1 DADSQNPDAPEGK 13 0 A0A3B3ISK1;A0A3B3ITV3;A0A3B3ISC6;A0A3B3IT15;A0A3B3IS84;P53621;P53621-2;A0A3B3IU89 A0A3B3ISK1 COPA Coatomer subunit alpha;Xenin;Proxenin 0 0 146.36 6.81E-16 0 442.79 343.37 365.08 316.03 486.1 374.74 403.56 264.23 326.91 393.72 FALSE FALSE TRUE 407.7427043 373.0493728 378.610186 314.7223516 480.303575 297.0146998 414.8828075 344.7925106 291.0487909 407.4017407 1.000836922 0.915679379 0.929328837 0.772511063 1.178943355 0.729046222 1.018362874 0.846320661 0.714402423 1 8.670308334 -7.261004629 18.22218927 1.000395183 0.915337319 0 0.148982384 1.459377512 61039.83087 0.017586544 0.020834625 5.48E-08 7.261004629 -0.085057864 DADSQNPDAPEGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 DADSQNPDAPEGKR 14 1 A0A3B3ISK1;A0A3B3ITV3;A0A3B3ISC6;A0A3B3IT15;A0A3B3IS84;P53621;P53621-2;A0A3B3IU89 A0A3B3ISK1 COPA Coatomer subunit alpha;Xenin;Proxenin 0 1 DADSQNPDAPEGK(1)R 132.31 0.00055726 360190 217.56 169.69 65.146 221.8 315.4 297.41 237.79 66.574 371.32 163.2 FALSE TRUE FALSE 200.3398964 184.3572475 67.56036807 220.8822504 311.639061 235.7238135 244.4617474 86.87210613 330.587125 168.8711879 1.186347411 1.091703385 0.400070426 1.307992519 1.845424699 1.395879407 1.447622596 0.514428229 1.957628943 1 7.399779392 -6.032398519 24.92793675 1.035420467 1.350436755 0.010964324 0.472945336 925.3475144 711976.0533 0.05507226 0.091379764 9.28E-07 6.032398519 0.315016289 DAEALSQRLEEK ddPTM_HeLa_Curcumin_4h_R1 1 DAEALSQRLEEK 12 1 P35580;P35580-5;P35580-2;P35580-3;P35580-4 P35580 MYH10 Myosin-10 0 0 100.93 0.0075703 12628000 2316.3 1813.3 2474.7 2436.1 2532 2546.9 2105.1 1727.8 2958.7 2222.9 FALSE FALSE TRUE 2132.962411 1970.033572 2566.414559 2426.020064 2501.807554 2018.644231 2164.16344 2254.598266 2634.138012 2300.14561 0.927316254 0.856482113 1.11576178 1.054724559 1.087673556 0.877615844 0.940881061 0.980198061 1.145204895 1 11.16750948 -6.768373298 24.99971429 0.956528488 1.005975436 0 0.09530648 337.1982383 1215742.141 0.01297879 0.017264459 1.70E-07 6.768373298 0.049446948 DAEDAMDAMDGAVLDGR ddPTM_HeLa_Curcumin_4h_R1 3 DAEDAMDAMDGAVLDGR 17 0 J3KP15;Q01130;J3QL05;Q01130-2 J3KP15 SRSF2 Serine/arginine-rich splicing factor 2 0 0 ;; ;; 338.47 8.32E-150 110989000 6515.79 5905.01 5784.1 6108.9 6270.7 7544.7 6622.9 6579.8 6425.2 5775.8 FALSE FALSE TRUE 6000.058346 6415.412752 5998.463834 6083.62299 6195.925998 5979.844174 6808.720749 8585.95073 5720.371635 5976.50862 1.003940382 1.073438216 1.003673585 1.017922566 1.036713304 1.000558111 1.139247206 1.436616472 0.957142706 1 12.54508722 -4.275086774 2.055613204 1.010209024 1.551828305 0.951802344 0.02897276 0.083015318 0.385682232 0.003424107 0.082674967 5.31E-05 4.275086774 0.541619281 DAEDDGEEEDD ddPTM_HeLa_Curcumin_4h_R1 4 DAEDDGEEEDD 11 0 Q5TB25;Q9BTT0-3;Q9BTT0-2;Q9BTT0;H0YCE2;Q5TB19 Q5TB25 ANP32E Acidic leucine-rich nuclear phosphoprotein 32 family member E 0 0 ;;; ;;; 182.39 0.0010649 334816400 37524 32879.3 33679.6 34664.3 33458 39466.1 30294.8 27702.3 37917.3 34776.5 FALSE FALSE TRUE 34553.9358 35721.24018 34927.7956 34520.86831 33059.0352 31280.38599 31144.79055 36148.60374 33757.86705 35984.98079 0.960232159 0.992670814 0.970621488 0.959313234 0.918689811 0.869262267 0.865494155 1.004546979 0.938109909 1 15.13510727 -5.854952812 2.507182029 0.980868728 0.906401364 0.312437521 0.039463028 0.192845475 2.464822525 0.005542612 0.011148578 1.40E-06 5.854952812 -0.074467364 DAEFYEHR ddPTM_HeLa_Curcumin_4h_R1 4 DAEFYEHR 8 0 O95340;O95340-2 O95340 PAPSS2 Bifunctional 3-phosphoadenosine 5-phosphosulfate synthase 2;Sulfate adenylyltransferase;Adenylyl-sulfate kinase 0 0 ;;; ;;; 141.52 4.23E-05 31876600 28563 22754.4 25928.8 24058.3 28040.4 29098.1 24146.2 25158.5 25194.8 23816.9 FALSE FALSE TRUE 26302.20841 24721.18894 26889.74414 23958.75313 27706.03654 23062.82606 24823.67739 32829.21083 22430.99347 24644.5355 1.067263305 1.003110363 1.091103711 0.972173045 1.124226364 0.93581906 1.007269031 1.332109134 0.910181223 1 14.58898017 -4.258944776 24.97017604 1.028971277 1.332109242 0.678661513 0.065110533 80.62919541 807022.0748 0.006880377 0.062688562 5.51E-05 4.258944776 0.303137965 DAEGILEDLQSYR ddPTM_HeLa_Curcumin_4h_R1 1 DAEGILEDLQSYR 13 0 E5RK61;E5RFS4;E5RHU5;E5RGI7;E5RJE1;E5RIR8;E5RJL8;E5RI16;Q9NUQ9 E5RK61 FAM49B Protein FAM49B 0 0 179.6 0.0013631 1828400 966.51 894.35 1053.3 1035.5 813.44 1413.1 1159.4 1045.5 989.77 1113.5 FALSE FALSE TRUE 890.0097136 971.6536289 1092.336225 1031.215375 803.7402593 1120.007131 1191.929644 1364.268137 881.1947073 1152.194042 0.772447766 0.843307284 0.94804884 0.895001482 0.697573698 0.972064678 1.034486901 1.184061093 0.764797139 1 10.17016799 -4.595467761 2.024678543 0.879484085 1.182047496 0.568862856 0.091406812 0.281070497 1.913412407 0.014969653 0.121755856 2.54E-05 4.595467761 0.30256341 DAGDPS(ph)PPNK ddPTM_HeLa_Curcumin_4h_R1 3 DAGDPSPPNK 10 0 Q9BTA9-2;Q9BTA9;A0A0A0MRT2;Q9BTA9-5;Q9BTA9-3;E9PMZ7;C9JMU2;A0A494C0B7;A0A494C0C1;A0A494C0S5;C9JVK6;C9JD58;J3QTA0 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 0 DAGDPS(1)PPNK;DAGDPS(1)PPNK;DAGDPS(1)PPNK ;; 140.45 0.0015018 297239000 27134.2 22849.9 24913.1 26567.6 25572.7 28347.9 23255 20860.4 27988.3 23672 TRUE FALSE FALSE 24986.49944 24824.94354 25836.4014 26457.67031 25267.76225 22468.22599 23907.47271 27220.63993 24918.05351 24494.60024 1.020081944 1.013486372 1.054779468 1.080142972 1.03156459 0.917272614 0.976030328 1.111291455 1.017287617 1 14.58017613 -4.248178427 24.14953506 1.011309168 1.11129156 0.336548973 0.041678357 1278.25468 2327767.26 0.005992394 0.14584331 5.65E-05 4.248178427 0.099982392 DAGQISGLNVLR ddPTM_HeLa_Curcumin_4h_R1 1 DAGQISGLNVLR 12 0 P38646 P38646 HSPA9 "Stress-70 protein, mitochondrial" 0 0 101.71 0.007675 2828100 731.17 697.33 694.04 816.15 926.95 1213.1 902.77 658.5 906.04 748.67 FALSE FALSE TRUE 673.297123 757.604098 719.7617329 812.7729876 915.8967267 961.4893855 928.0992965 859.2736186 806.6496788 774.6862268 0.869122362 0.977949616 0.929100981 1.049164112 1.182280896 1.241133961 1.198032525 1.109189229 1.041259869 1 9.59746828 -5.957494408 2.559069201 0.939570172 1.189733652 0.774286196 0.054914645 0.089722648 1.189028165 0.00882509 0.016914286 1.10E-06 5.957494408 0.25016348 DAGTIAGLNVLR ddPTM_HeLa_Curcumin_4h_R1 3 DAGTIAGLNVLR 12 0 P11142;E9PKE3;P11142-2;E9PN89;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 ;; ;; 219.72 1.21E-28 36003300 4096.3 2970.29 3175.7 3137.62 3567.35 5124.8 4216.86 3973.02 3544.23 3388.06 FALSE FALSE TRUE 3772.073533 3227.028632 3293.394236 3124.63736 3524.811681 4061.858712 4335.173743 5184.375508 3155.436836 3505.794833 1.075953874 0.920484166 0.939414425 0.891277872 1.005424404 1.158612784 1.236573716 1.478801743 0.900063177 1 11.77552585 -4.484904132 1.315579273 1.008290598 1.564257415 0.842238289 0.070065756 0.292661788 0.578806291 0.010915079 0.194003232 3.27E-05 4.484904132 0.555966817 DAGVIAGLNVLR ddPTM_HeLa_Curcumin_4h_R1 1 DAGVIAGLNVLR 12 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;Q53FA3;P34931 A0A0G2JIW1 HSPA1B;HSPA1A;HSPA1L Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 1-like 0 0 139.38 0.00015701 2476000 1045.4 951.68 1064.2 1255.4 792.78 1444.5 769.16 752.92 975.7 808.51 FALSE FALSE TRUE 962.6554869 1033.938979 1103.640188 1250.205487 783.3266163 1144.894417 790.7405595 982.481842 868.6681511 836.6056623 1.150668147 1.235873752 1.319188045 1.494378467 0.936315222 1.368499484 0.945177155 1.174366713 1.038324494 1 9.708403952 -8.390983955 0.92185694 1.019612105 1.20638078 0.16822404 0.16387575 0.62080227 1.09735666 0.056428674 0.033696383 4.06E-09 8.390983955 0.186768675 DAHDVS(ph)PT(ph)STDTEAQLTVER ddPTM_HeLa_Curcumin_4h_R1 1 DAHDVSPTSTDTEAQLTVER 20 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 2 0 DAHDVS(0.988)PT(0.474)S(0.474)T(0.044)DT(0.02)EAQLTVER 157.42 5.23E-11 0 2023 1842.6 1636 1767.1 1705.5 2784.1 2282.7 1320.6 2435.1 2042.8 TRUE FALSE FALSE 1862.877415 2001.866134 1696.631599 1759.788208 1685.163026 2206.646277 2346.746418 1723.244861 2167.975622 2113.787148 0.881298487 0.947051899 0.802650163 0.832528578 0.797224559 1.043930217 1.110209427 0.815240485 1.025635729 1 11.04561439 -3.960941354 21.5605761 0.93246763 0.000220917 0.111973924 0.102576328 1988.058507 393951.3579 0.014232762 109316.3077 0.00010941 3.960941354 -0.932246712 DAHDVS(ph)PTST(ph)DTEAQLTVER ddPTM_HeLa_Curcumin_4h_R1 1 DAHDVSPTSTDTEAQLTVER 20 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 2 0 DAHDVS(0.991)PT(0.015)S(0.247)T(0.742)DT(0.006)EAQLTVER 101.3 0.00049137 18315000 1136.8 1121.6 888.41 1200.1 1216 1547.1 1450.2 896.67 1217.2 1547.7 TRUE FALSE FALSE 1046.82108 1218.546106 921.3352561 1195.134304 1201.499994 1226.214021 1490.888709 1170.060555 1083.676205 1601.48246 0.653657537 0.760886327 0.575301497 0.746267495 0.750242369 0.765674337 0.93094289 0.730610909 0.676670668 1 10.64519228 -9.396878619 1.096527874 1.001506844 0.735332051 0 0.13010792 0.312128205 0.665241457 0.064105756 0.015984009 4.01E-10 9.396878619 -0.266174793 DAHDVS(ph)PTSTDTEAQLTVER ddPTM_HeLa_Curcumin_4h_R1 9 DAHDVSPTSTDTEAQLTVER 20 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 DAHDVS(1)PTSTDTEAQLTVER;DAHDVS(1)PTSTDTEAQLTVER;DAHDVS(0.993)PT(0.007)STDTEAQLTVER;DAHDVS(0.953)PT(0.03)S(0.012)T(0.005)DT(0.001)EAQLTVER;DAHDVS(0.862)PT(0.13)S(0.006)T(0.002)DTEAQLTVER;DAHDVS(0.978)PT(0.018)S(0.003)T(0.001)DTEAQLTVER;DAHDVS(0.491)PT(0.491)S(0.014)T(0.003)DTEAQLTVER;DAHDVS(0.998)PT(0.002)STDTEAQLTVER;DAHDVS(1)PTSTDTEAQLTVER ;;;;;;;; 235.72 5.42E-26 3640065100 25320.84 22346 21722.48 24461.5 24017 27967.1 21490.94 20962.66 27225.3 23203.3 TRUE FALSE FALSE 23316.6688 24277.48867 22527.53422 24360.28479 23730.61296 22166.40821 22093.91794 27354.07853 24238.7527 24009.61295 0.971138887 1.01115702 0.938271444 1.014605477 0.988379655 0.923230552 0.920211333 1.139296939 1.009543667 1 14.55132453 -9.602814609 1.395227698 1.000019013 0.98204868 0.001647665 0.060085564 2.347977085 8.187705523 0.039393838 0.009052099 2.50E-10 9.602814609 -0.017970334 DAINQGMDEELERDEK ddPTM_HeLa_Curcumin_4h_R1 3 DAINQGMDEELERDEK 16 1 P11177-3;P11177-2;P11177;F8WF02;C9J634 P11177-3 PDHB "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial" 0 0 ;; ;; 199.65 3.72E-08 93818000 4553.1 3474.5 3941.3 4716.1 4135.8 7318.8 5140.1 3704.73 5001.3 3509.2 FALSE FALSE TRUE 4192.717331 3774.820298 4087.368045 4696.586028 4086.483286 5800.79838 5284.317372 4834.285123 4452.669903 3631.144439 1.154654518 1.039567652 1.125641823 1.293417573 1.125398164 1.597512431 1.455276005 1.331339252 1.226244226 1 11.8262086 -5.743378453 1.062380472 1.071658676 1.456759202 0.577566178 0.115638564 0.229258693 0.500060298 0.017867123 0.054526179 1.81E-06 5.743378453 0.385100526 DALDGPAAEAEPEHSFDGLRR ddPTM_HeLa_Curcumin_4h_R1 3 DALDGPAAEAEPEHSFDGLRR 21 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ;; ;; 129.88 4.39E-06 47633000 13269.6 10036.8 11128.3 11799.3 11243.4 14303.4 10064.9 9625.1 14741.6 12632.7 FALSE FALSE TRUE 12219.29716 10904.33627 11540.72459 11750.47762 11109.3298 11336.71361 10347.29401 12559.74868 13124.48336 13071.68538 0.934791253 0.834195128 0.882879617 0.898925982 0.849877385 0.867272526 0.791580711 0.960836213 1.00403911 1 13.67415755 -7.825034515 0.824310145 0.988978271 0.864621942 0.570301531 0.04428419 0.254832272 0.374203172 0.012212918 0.01024011 1.50E-08 7.825034515 -0.124356328 DALFPAEGGAADCES(ph)PREFR ddPTM_HeLa_Curcumin_4h_R1 1 DALFPAEGGAADCESPREFR 20 1 Q8TF30 Q8TF30 WHAMM "WASP homolog-associated protein with actin, membranes and microtubules" 1 0 DALFPAEGGAADCES(1)PREFR 66.711 0.0034515 2948800 808.84 726.01 781.14 813.75 812.42 897.34 687.04 483.5 922.32 1083.6 TRUE FALSE FALSE 744.8194605 788.7630694 810.0897356 810.3829181 802.7324221 711.2215689 706.3164933 630.9169242 821.1438035 1121.255019 0.664273022 0.703464471 0.722484824 0.722746301 0.715923147 0.634308482 0.629933852 0.56268816 0.732343481 1 10.13089873 -13.52287874 0.214327039 2.728797363 0.617241047 0.226285031 0.096722341 11.52603085 0.144432522 8.320971938 0.041766918 3.00E-14 13.52287874 -2.111556316 DALGDSLQVPVS(ph)PSS(ph)TTSSR ddPTM_HeLa_Curcumin_4h_R1 2 DALGDSLQVPVSPSSTTSSR 20 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 2 0 DALGDSLQVPVS(0.978)PS(0.106)S(0.75)T(0.155)T(0.009)S(0.002)SR;DALGDSLQVPVS(1)PS(0.414)S(0.463)T(0.108)T(0.014)S(0.002)SR ; 149.12 0.00010485 12370000 4205.3 3256.89 4021.9 3292.4 3542.67 3440.9 2371.4 3686.4 4180.1 4328.2 TRUE FALSE FALSE 3872.446068 3538.401059 4170.955152 3278.776921 3500.425974 2727.218553 2437.935102 4810.36639 3721.553488 4478.604628 0.864654594 0.790067745 0.931306846 0.732097873 0.781588523 0.608943807 0.54435149 1.074077037 0.830962721 1 12.1288336 -7.58629982 0.414863831 0.999934617 0.72358588 0.09896202 0.147637365 0.859515138 0.400375547 0.08452553 0.072926993 2.59E-08 7.58629982 -0.276348737 DALGDSLQVPVS(ph)PSSTTSSR ddPTM_HeLa_Curcumin_4h_R1 5 DALGDSLQVPVSPSSTTSSR 20 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 DALGDSLQVPVS(0.964)PS(0.035)S(0.001)TTSSR;DALGDSLQVPVS(0.808)PS(0.139)S(0.037)T(0.01)T(0.002)S(0.003)S(0.001)R;DALGDSLQVPVS(0.971)PS(0.016)S(0.005)T(0.001)T(0.005)S(0.001)S(0.001)R;DALGDSLQVPVS(0.967)PS(0.019)S(0.009)T(0.003)T(0.001)SSR;DALGDSLQVPVS(0.744)PS(0.226)S(0.03)T(0.001)TSSR ;;;; 209.73 8.15E-49 1405281000 18205 14766.2 15071.91 14971.3 15681.5 17842.95 15796.9 24042.4 18520.4 15778.9 TRUE FALSE FALSE 16764.05504 16042.52453 15630.48824 14909.35273 15494.50835 14142.12104 16240.1185 31372.81708 16488.75846 16327.2156 1.026755293 0.982563404 0.95732724 0.913159542 0.948998821 0.866168573 0.994665526 1.921504429 1.009894085 1 13.99499116 -4.261616442 7.944705499 0.98537491 1.929312515 0.971397181 0.049064005 0.012471596 9.36201309 0.007961857 0.063027635 5.47E-05 4.261616442 0.943937605 DALGDSLQVPVSPS(ph)STTSSR ddPTM_HeLa_Curcumin_4h_R1 1 DALGDSLQVPVSPSSTTSSR 20 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 DALGDSLQVPVS(0.28)PS(0.533)S(0.153)T(0.013)T(0.013)S(0.004)S(0.004)R 160.95 1.27E-15 0 563.96 729.13 370.68 679.51 398.29 486.22 493.58 606.49 684.96 502.43 TRUE FALSE FALSE 519.3219709 792.1527483 384.4177269 676.6983677 393.5406519 385.3724912 507.4285264 791.4060091 609.8216017 519.8894051 0.998908548 1.523694733 0.739422122 1.301619847 0.75696994 0.741258597 0.976031674 1.522258391 1.172983322 1 9.022060944 DALNIETAIK ddPTM_HeLa_Curcumin_4h_R1 1 DALNIETAIK 10 0 H0YMW4;P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4;P07355-2 H0YMW4;P07355;P07355-2 ANXA2;ANXA2P2 Annexin;Annexin A2;Putative annexin A2-like protein 0 0 143.5 1.73E-05 12174000 5650.3 5726.8 5168.9 6085.4 9552.7 2281.5 3908.9 5036.2 9977.1 5132.4 FALSE FALSE TRUE 5203.072793 6221.799074 5360.463981 6060.220227 9438.790292 1808.291182 4018.573214 6571.714196 8882.637091 5310.750518 0.979724575 1.171547986 1.009360911 1.141123125 1.777298756 0.340496353 0.756686498 1.23743606 1.672576609 1 12.37470004 -3.925147168 17.54572403 1.010621316 5.906170853 0 0.397935497 273.0161902 65247.29046 0.043429792 1006.817449 0.00011881 3.925147168 4.895549536 DALQDS(ph)LAR ddPTM_HeLa_Curcumin_4h_R1 1 DALQDSLAR 9 0 Q96A99-2;Q96A99 Q96A99-2 PTX4 Pentraxin-4 1 0 DALQDS(1)LAR 99.136 0.013637 9337800 1917.3 1395.6 1712.4 1899.9 1649.5 1876.2 1466.7 1324.8 1853.3 1670.1 TRUE FALSE FALSE 1765.543682 1516.229445 1775.86305 1892.038717 1629.83079 1487.054971 1507.851655 1728.725421 1649.997627 1728.135851 1.021646349 0.877378619 1.027617736 1.09484374 0.943114969 0.860496569 0.872530741 1.00034116 0.954784675 1 10.75500092 -5.532399483 24.95238496 1.006642198 0.906353965 0.262520938 0.063219861 153.9988555 403606.661 0.008619015 0.017254954 2.93E-06 5.532399483 -0.100288233 DALTAEK(ac)SK ddPTM_HeLa_Curcumin_4h_R1 2 DALTAEKSK 9 1 Q9HB71;B2ZWH1;Q9HB71-2 Q9HB71 CACYBP Calcyclin-binding protein 0 1 ; DALTAEK(1)SK;DALTAEK(1)SK 102.06 0.0073829 2675300 1284.44 872.42 1209.88 1164.61 1216.23 1325.73 1063 1321.49 1252.45 1160.1 FALSE TRUE FALSE 1182.775219 947.8280974 1254.719217 1159.791152 1201.727252 1050.758654 1092.824919 1724.406218 1115.059368 1200.413389 0.985306587 0.789584743 1.045239273 0.966159794 1.001094509 0.875330668 0.910373817 1.436510317 0.928896144 1 10.2293156 -4.257004806 24.98213035 0.969604597 1.436510505 0.79602509 0.073725651 149.9573317 844752.0078 0.009905726 0.10480274 5.53E-05 4.257004806 0.466905908 DANGNSFATR ddPTM_HeLa_Curcumin_4h_R1 1 DANGNSFATR 10 0 C9JEH7;Q8TD47;P62701;P22090 C9JEH7 RPS4Y1;RPS4Y2;RPS4X "40S ribosomal protein S4, Y isoform 2;40S ribosomal protein S4, X isoform;40S ribosomal protein S4, Y isoform 1" 0 0 133.75 0.00094261 4936100 1075.8 898.69 795.39 841.1 956.77 939.95 908.96 586.26 960.58 697.23 FALSE FALSE TRUE 990.6492948 976.3687591 824.8678531 837.6197511 945.3611426 744.9937746 934.4629713 765.0079752 855.2067773 721.4586906 1.373119913 1.353325938 1.143333449 1.161008609 1.310346878 1.032621527 1.295241132 1.060362825 1.185385648 1 9.494772981 -4.220139226 21.22219624 1.193407112 1.060360011 0.106112817 0.121981762 7556.087583 3882130.486 0.021513012 6.621305238 6.02E-05 4.220139226 -0.133047101 DAPAGS(ph)PPASPGPQGPSTK ddPTM_HeLa_Curcumin_4h_R1 1 DAPAGSPPASPGPQGPSTK 19 0 A0A0A0MRX4;Q3MIN7;Q3MIN7-2 A0A0A0MRX4 RGL3 Ral guanine nucleotide dissociation stimulator-like 3 1 0 DAPAGS(1)PPASPGPQGPSTK 173.49 2.71E-06 5441600 1775.2 1484 1658.9 1474.4 1433.4 1773.5 878.38 678.5 1852.2 1522.3 TRUE FALSE FALSE 1634.691047 1612.270347 1720.380293 1468.299323 1416.307641 1405.656109 903.0249788 885.3715266 1649.018294 1575.199812 1.037767421 1.023533862 1.092166391 0.932135284 0.899128879 0.892366859 0.573276464 0.562069345 1.046862932 1 10.62131913 -4.805623066 1.054450819 1.020746877 0.459972785 0.916765062 0.051964685 0.155990947 0.231826097 0.007551619 0.078783003 1.56E-05 4.805623066 -0.560774092 DAPIS(ph)PASIASSSSTPS(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 DAPISPASIASSSSTPSSK 19 0 Q04727-4;Q04727;Q04727-3;H7C4E4;H0Y5S0 Q04727-4 TLE4 Transducin-like enhancer protein 4 2 0 DAPIS(0.997)PAS(0.003)IAS(0.001)S(0.001)S(0.008)S(0.024)T(0.287)PS(0.543)S(0.137)K 93.215 0.0013823 0 1133.3 1098.6 1209.7 1345.4 1148.4 1462.9 1468.4 553.12 1369.9 937.33 TRUE FALSE FALSE 1043.598109 1193.558089 1254.532546 1339.833091 1134.70608 1159.47805 1509.599352 721.7637417 1219.625397 969.9021477 1.075982883 1.230596397 1.293463005 1.381410583 1.169918102 1.195458792 1.556445004 0.744161402 1.257472623 1 9.921695393 -7.358516327 2.470177068 1.030204774 1.244474927 0.014387655 0.207328952 0.318037293 3.66150057 0.031976935 0.036576928 4.38E-08 7.358516327 0.214270154 DAPIS(ph)PASIASSSSTPSSK ddPTM_HeLa_Curcumin_4h_R1 2 DAPISPASIASSSSTPSSK 19 0 Q04727-4;Q04727;Q04727-3;H7C4E4;H0Y5S0 Q04727-4 TLE4 Transducin-like enhancer protein 4 1 0 DAPIS(0.961)PAS(0.039)IASSSSTPSSK;DAPIS(0.998)PAS(0.002)IASSSSTPSSK ; 282.67 4.96E-69 34555000 12180.8 10039.1 10457.4 11364.2 10352.7 11905.5 7894.3 5428.1 12509.2 10654.9 TRUE FALSE FALSE 11216.67683 10906.83507 10844.96044 11317.17795 10229.25081 9436.165097 8115.792812 7083.102702 11136.97206 11025.15698 1.017371167 0.989268007 0.983655875 1.026486786 0.927809992 0.855875804 0.736115851 0.642449147 1.010141812 1 13.42851158 -4.788820147 1.032693124 1.007329602 0.592020015 0.982505834 0.01668881 0.076119713 0.105793666 0.002568066 0.028277941 1.63E-05 4.788820147 -0.415309587 DAPISPAS(ph)IASSSSTPSSK ddPTM_HeLa_Curcumin_4h_R1 1 DAPISPASIASSSSTPSSK 19 0 Q04727-4;Q04727;Q04727-3;H7C4E4;H0Y5S0 Q04727-4 TLE4 Transducin-like enhancer protein 4 1 0 DAPIS(0.046)PAS(0.951)IAS(0.002)SSSTPSSK 124.84 0.0001666 18883000 1988.2 1405 2043.9 1948.9 1994.7 2102.9 1190.7 1033.2 2444 1841.9 TRUE FALSE FALSE 1830.831872 1526.441939 2119.648732 1940.835968 1970.914505 1666.734835 1224.107837 1348.217924 2175.899315 1905.905888 0.960609799 0.800901004 1.112147638 1.018327285 1.034109039 0.874510565 0.642270872 0.707389558 1.141661468 1 10.89626117 -4.917470431 3.671078653 0.982605757 0.675388717 0.674056729 0.091085145 0.084136143 2.212735754 0.010449764 0.035022121 1.21E-05 4.917470431 -0.307217039 DAPQDFHPDR ddPTM_HeLa_Curcumin_4h_R1 3 DAPQDFHPDR 10 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ;; ;; 127.51 0.00051268 133408000 15662.9 9248.8 14848.2 11920.2 14545.9 18121.1 13953.9 13285 12727 11796.1 FALSE FALSE TRUE 14423.16494 10048.22506 15398.48735 11870.87737 14372.44964 14362.57959 14345.40888 17335.53534 11330.87994 12206.0136 1.181644181 0.823219226 1.261549255 0.972543351 1.177489237 1.176680616 1.175273873 1.420245456 0.928303074 1 13.57530448 -1 0.615477916 1.073127872 24.53654221 0.445808359 0.125419263 121.0241395 0.818543578 0.020045644 3846.249404 0.1 1 23.46341434 DAPSLEEVEGHVADGS(ph)ATEMGTTK ddPTM_HeLa_Curcumin_4h_R1 1 DAPSLEEVEGHVADGSATEMGTTK 24 0 C9J470;E9PHA2;Q15003;Q15003-2 C9J470 NCAPH Condensin complex subunit 2 1 0 DAPSLEEVEGHVADGS(0.911)AT(0.087)EMGT(0.001)T(0.001)K 138.46 1.22E-06 28171000 3355.7 2758.2 3314.4 3199.6 3473.1 4871.7 2900.3 1303.2 3785.6 3227.8 TRUE FALSE FALSE 3090.092804 2996.606518 3437.23458 3186.360903 3431.685551 3861.254505 2981.674612 1700.539681 3370.329151 3339.96581 0.925186957 0.897196764 1.029122684 0.954010036 1.027461281 1.156076057 0.892726088 0.509148829 1.009090914 1 11.70561762 -4.291881172 3.815562755 0.978868368 0.475448827 0.812302533 0.06996134 0.074075277 2.050558024 0.009997938 0.098417411 5.11E-05 4.291881172 -0.503419541 DAPSLEEVEGHVADGSAT(ph)EMGTTK ddPTM_HeLa_Curcumin_4h_R1 1 DAPSLEEVEGHVADGSATEMGTTK 24 0 C9J470;E9PHA2;Q15003;Q15003-2 C9J470 NCAPH Condensin complex subunit 2 1 0 DAPSLEEVEGHVADGS(0.348)AT(0.443)EMGT(0.169)T(0.04)K 75.174 0.00066593 10556000 1648.3 1265 1060.2 1474.8 1693.7 1748.5 1235.1 576.73 1571.7 1098.1 TRUE FALSE FALSE 1517.835316 1374.340963 1099.491945 1468.697668 1673.503734 1385.84139 1269.753582 752.5723221 1399.288442 1136.258893 1.335818205 1.209531535 0.967642103 1.29257309 1.472819041 1.219652844 1.117486155 0.662324692 1.23148734 1 10.15007587 -4.265717447 3.484111449 1.186756074 0.600519341 0.569323103 0.142081891 0.205189678 4.291106112 0.023801444 0.314133998 5.42E-05 4.265717447 -0.586236733 DAPT(ph)SPASVASSSSTPSSK ddPTM_HeLa_Curcumin_4h_R1 1 DAPTSPASVASSSSTPSSK 19 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 0 DAPT(0.914)S(0.084)PAS(0.002)VASSSSTPSSK 276.3 3.93E-68 112580000 6109.1 5256.3 5733.6 5470.2 5993.5 7078.9 5621.3 5147.1 6758.2 5078.8 TRUE FALSE FALSE 5625.558289 5710.63115 5946.09226 5447.565762 5922.031427 5610.656344 5779.018549 6716.427096 6016.842368 5255.287922 1.070456723 1.086644773 1.13144938 1.036587499 1.126870975 1.067621114 1.099657837 1.278032183 1.144912031 1 12.35955409 -1 0.174717815 1.002250236 1.776010593 0.225069941 0.063091326 32.74198911 0.349494959 0.06726025 6.709088674 0.1 1 0.773760358 DAPTS(ph)PAS(ph)VASSSSTPSSK ddPTM_HeLa_Curcumin_4h_R1 1 DAPTSPASVASSSSTPSSK 19 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 2 0 DAPT(0.145)S(0.851)PAS(0.86)VAS(0.073)S(0.023)S(0.021)S(0.013)T(0.011)PS(0.001)SK 93.768 0.0013104 0 911.47 727.73 848.84 673.24 797.32 789.44 672.11 383.03 734.53 865.23 TRUE FALSE FALSE 839.3261877 790.6317385 880.2987571 670.4543113 787.8124797 625.7012452 690.9675977 499.8140837 653.9538967 895.2966781 0.937483862 0.883094686 0.983248099 0.748862726 0.87994572 0.69887587 0.771775004 0.558266434 0.730432618 1 9.806222023 -3.266157302 0.282963686 0.996812006 7.65E-22 0.415603086 0.102278843 3.9293544 0.150951532 0.025613614 1.507417304 0.000541805 3.266157302 -0.996812006 DAPTS(ph)PASVAS(ph)SSSTPSSK ddPTM_HeLa_Curcumin_4h_R1 1 DAPTSPASVASSSSTPSSK 19 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 2 0 DAPT(0.045)S(0.739)PAS(0.265)VAS(0.467)S(0.385)S(0.065)S(0.022)T(0.007)PS(0.002)S(0.001)K 80.541 0.010428 46131000 2279.4 1827.3 1863 2245.7 2341.3 3232.8 1964.7 1055.5 2438.3 1839.9 TRUE FALSE FALSE 2098.983085 1985.24367 1932.044419 2236.407888 2313.381527 2562.280839 2019.824194 1377.317091 2170.82459 1903.836388 1.102501821 1.0427596 1.014816415 1.174684916 1.215115722 1.345851385 1.060923201 0.723442991 1.140236947 1 10.89469379 -6.272131944 24.0942577 1.046830011 1.121219165 0.010224751 0.154614027 1173.04795 2643300.516 0.023835866 0.036660588 5.34E-07 6.272131944 0.074389154 DAPTS(ph)PASVASSSSTPSSK ddPTM_HeLa_Curcumin_4h_R1 1 DAPTSPASVASSSSTPSSK 19 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 0 DAPT(0.044)S(0.936)PAS(0.02)VASSSSTPSSK 149.19 7.97E-05 202450000 3185.2 2501.5 3192.4 2908.5 2829.3 3939.3 2824.8 2850.6 3370.8 3193.6 TRUE FALSE FALSE 2933.088059 2717.718514 3310.713152 2896.465398 2795.562445 3122.244775 2904.056285 3719.734817 3001.031673 3304.577362 0.887583415 0.822410316 1.001856755 0.876501011 0.845966712 0.944824234 0.878798093 1.125631029 0.90814387 1 11.69025006 -4.252762728 24.33609719 0.926318864 1.125631178 0.52897008 0.059415149 565.2047613 1585223.387 0.009262068 0.143473208 5.59E-05 4.252762728 0.199312314 DAQHYGGWEHR ddPTM_HeLa_Curcumin_4h_R1 1 DAQHYGGWEHR 11 0 F5H6X6;Q14697;Q14697-2;E9PKU7 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 0 135.1 0.00060649 11589000 4506.5 4193.6 4937.1 4329.7 5069.4 8445.6 4537.3 2687.4 4228.8 4787.1 FALSE FALSE TRUE 4149.80577 4556.076098 5120.073269 4311.784849 5008.950716 6693.887358 4664.604426 3506.775889 3764.91122 4953.451369 0.837760475 0.919778102 1.033637536 0.870460721 1.011204177 1.351358247 0.94168774 0.707945961 0.760058178 1 12.27421837 -5.644030637 7.981084034 0.927295429 1.024995466 0.064455256 0.164278446 0.521665091 34.3781086 0.023229171 0.046551748 2.27E-06 5.644030637 0.097700037 S(ph)PSSQTPNSR ddPTM_HeLa_Curcumin_4h_R1 2 SPSSQTPNSR 10 0 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 0 S(1)PSSQTPNSR;S(0.999)PS(0.001)SQTPNSR ; 145.14 0.0011546 74747000 919.15 982.73 861.33 785.38 879.95 664.55 300.57 0 510.1 944.87 TRUE FALSE FALSE 846.3983076 1067.672802 893.2516475 782.1303057 869.457171 526.714839 309.0031853 0 454.1433062 977.7041622 0.86569981 1.09202031 0.913621607 0.799966223 0.889284514 0.538726191 0.31604978 0 0.464499717 1 9.933254184 -4.847606081 1.196086932 0.942283743 7.75E-16 0.734313793 0.169396233 0.11586106 0.246440931 0.012356886 0.104138054 1.42E-05 4.847606081 -0.942283743 down DAQQVEPEGQEKPS(ph)PATVR ddPTM_HeLa_Curcumin_4h_R1 1 DAQQVEPEGQEKPSPATVR 19 1 E7EPN9;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;Q9Y520-2;A0A2R8Y7F4;A0A2R8YET2;H7C5N8 E7EPN9 PRRC2C Protein PRRC2C 1 0 DAQQVEPEGQEKPS(0.951)PAT(0.049)VR 76.21 0.0027576 14395000 1559.9 1243 1520.9 1540.5 1576 2754.2 3291.8 1075.5 1624.3 1399.6 TRUE FALSE FALSE 1436.432269 1350.439381 1577.265892 1534.125819 1557.207229 2182.947874 3384.159049 1403.414999 1446.118354 1448.235996 0.991849583 0.932471907 1.089094524 1.059306511 1.075244113 1.507315023 2.336745571 0.969051317 0.998537778 1 10.500081 -5.209118122 3.693670945 1.005669263 1.704108972 0.424676815 0.311165654 0.13124146 3.671379177 0.038458302 0.103258935 6.18E-06 5.209118122 0.698439709 DAQRLS(ph)PIPEEVPK ddPTM_HeLa_Curcumin_4h_R1 2 DAQRLSPIPEEVPK 14 1 Q96T23-3;Q96T23-2;Q96T23;H0YER1;H0YCN2 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 0 DAQRLS(1)PIPEEVPK;DAQRLS(1)PIPEEVPK ; 88.283 0.0050456 161116000 14841 13589.4 14711.6 14653.9 16547.9 15318.5 13570.4 11471.5 13006.2 12225.7 TRUE FALSE FALSE 13666.31919 14764.00718 15256.82484 14593.26604 16350.5771 12141.27042 13951.1489 14969.10754 11579.4524 12650.54216 1.080295138 1.167065173 1.206021421 1.153568428 1.292480345 0.95974309 1.102810355 1.183277945 0.915332501 1 13.6269116 -7.847800107 1.164011128 1.019962461 1.149236739 0.393356766 0.087565166 0.362288495 1.029864272 0.019855259 0.0177467 1.42E-08 7.847800107 0.129274278 DAS(ph)DGEDEKPPLPPR ddPTM_HeLa_Curcumin_4h_R1 1 DASDGEDEKPPLPPR 15 1 O15357 O15357 INPPL1 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2" 1 0 DAS(1)DGEDEKPPLPPR 65.511 0.015911 11318000 2576.9 2759.1 2576.5 2579.4 3013.8 2763.1 1800.2 2032.4 2744.1 2262.9 TRUE FALSE FALSE 2372.935646 2997.58431 2671.987357 2568.727126 2977.862403 2190.001913 1850.708767 2652.069404 2443.079095 2341.535607 1.01341002 1.280178828 1.141126084 1.09702672 1.271756191 0.935284481 0.7903825 1.13261972 1.043366195 1 11.19323926 -3.912665408 21.57461309 1.039306763 8.2834239 0 0.141692245 3384.417241 842583.6926 0.019762908 9370.413599 0.000122274 3.912665408 7.244117137 DAS(ph)EETSTSVMQK ddPTM_HeLa_Curcumin_4h_R1 2 DASEETSTSVMQK 13 0 M0QZH1;M0QX70;M0QYR7;M0R2N0;M0QZC7;Q9H0W8-2;Q9H0W8 M0QZH1 SMG9 Protein SMG9 1 0 DAS(0.999)EET(0.001)STSVMQK;DAS(0.999)EET(0.001)STSVMQK ; 130.19 0.0016399 36638000 9870 10713.4 9021.6 8886 9168.5 9062.2 8075.8 7073.1 9501.8 12079.9 TRUE FALSE FALSE 9088.779085 11639.41856 9355.948432 8849.232086 9059.171626 7182.597568 8302.385213 9229.655629 8459.476312 12499.67563 0.727121196 0.931177649 0.748495298 0.707956938 0.724752537 0.574622717 0.664208053 0.738391612 0.676775667 1 13.60960304 -13.52287875 0.146455312 2.043343401 0.613144671 0 0.123913064 29.6967611 0.298665597 8.929250077 0.193857752 3.00E-14 13.52287875 -1.43019873 DAS(ph)PTPSTDAEYPANGSGADR ddPTM_HeLa_Curcumin_4h_R1 2 DASPTPSTDAEYPANGSGADR 21 0 E9PEE2;E7EPF5;O43639 E9PEE2 NCK2 Cytoplasmic protein NCK2 1 0 DAS(0.999)PT(0.001)PSTDAEYPANGSGADR;DAS(1)PTPSTDAEYPANGSGADR ; 263.19 2.15E-59 34413000 1648.08 1517.29 1380.11 1423.87 1618.49 1826.89 1574.75 1638.22 1693.25 1296.43 TRUE FALSE FALSE 1517.632729 1648.437787 1431.258091 1417.978403 1599.190564 1447.972421 1618.933247 2137.705737 1507.504711 1341.480846 1.131311516 1.228819473 1.066923985 1.057024711 1.192108384 1.079383597 1.206825466 1.593541751 1.123761637 1 10.38961074 -4.149277808 1.798134482 1.083941484 1.872815433 0.819035387 0.067097931 0.401861987 1.025664884 0.011189486 0.586421377 7.09E-05 4.149277808 0.788873949 DASDDLDDLNFFNQK ddPTM_HeLa_Curcumin_4h_R1 1 DASDDLDDLNFFNQK 15 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 0 0 236.11 1.06E-20 10467000 1505.4 1498.6 1381.8 1528.9 1504.9 2036.9 1726.5 1455.7 1447 1144.6 FALSE FALSE TRUE 1386.246002 1628.132306 1433.010724 1522.573817 1486.95505 1614.423979 1774.940943 1899.536229 1288.26772 1184.374765 1.170445405 1.374676627 1.209930139 1.285550708 1.255476809 1.363102311 1.498631173 1.60383038 1.087719663 1 10.20990994 -1 0.128929705 0.893544534 3.117268572 0.832924204 0.070939764 21.09154294 0.183800343 0.24920841 8.548431024 0.1 1 2.223724038 LEAS(ph)YSDSPPGEEDLLVHVAEGSK ddPTM_HeLa_Curcumin_4h_R1 3 LEASYSDSPPGEEDLLVHVAEGSK 24 0 Q7Z3C6;C9JS65;C9JFV2;F2Z3I6;C9JX27;C9IYZ9;C9JKV7;C9JDK4;C9JXG2;Q7Z3C6-3 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 0 LEAS(0.99)YS(0.01)DSPPGEEDLLVHVAEGSK;LEAS(0.927)YS(0.071)DS(0.002)PPGEEDLLVHVAEGSK;LEAS(0.974)YS(0.019)DS(0.007)PPGEEDLLVHVAEGSK ;; 200.97 8.52E-19 32317800 14364.9 11704 14178.3 15747 12646.9 11693.1 3917.64 846.94 14300 15074.8 TRUE FALSE FALSE 13227.90301 12715.64161 14703.76027 15681.84309 12496.09398 9267.819252 4027.558435 1105.168107 12731.32578 15598.64818 0.848015986 0.815175871 0.942630419 1.005333469 0.801101085 0.594142463 0.258199197 0.070850249 0.816181353 1 13.92913339 -4.846398195 1.387784445 0.923721922 0.028676395 0.947654816 0.068672122 0.088543955 0.276126104 0.01135823 0.081787903 1.42E-05 4.846398195 -0.895045527 down DASVPLIDVT(ph)NLPTPR ddPTM_HeLa_Curcumin_4h_R1 1 DASVPLIDVTNLPTPR 16 0 Q96A65;Q96A65-2 Q96A65 EXOC4 Exocyst complex component 4 1 0 DASVPLIDVT(0.845)NLPT(0.155)PR 102.29 0.0067051 11438000 2594.6 2073.8 2385.9 2502.2 1978.9 4138 3577.6 1764.8 3030.1 2153.8 TRUE FALSE FALSE 2389.234672 2253.050031 2474.323553 2491.846559 1955.30291 3279.732155 3677.977827 2302.879396 2697.705611 2228.64439 1.072057383 1.010950891 1.110237041 1.118099671 0.877350787 1.471626505 1.650320636 1.033309489 1.210469298 1 11.12195072 -5.252057902 24.98683512 1.036273762 1.411609078 0.445708144 0.165740781 349.8549722 931809.1498 0.019893123 0.04997769 5.60E-06 5.252057902 0.375335315 DASVPLIDVTNLPT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 DASVPLIDVTNLPTPR 16 0 Q96A65;Q96A65-2 Q96A65 EXOC4 Exocyst complex component 4 1 0 DASVPLIDVTNLPT(1)PR;DASVPLIDVTNLPT(1)PR;DASVPLIDVT(0.006)NLPT(0.994)PR ;; 215.49 1.10E-14 32206000 8065.4 7247.8 7352.1 8203.1 8511.9 12667.5 13070.1 6236.4 8127.3 6634.7 TRUE FALSE FALSE 7427.015079 7874.267536 7624.575294 8169.157746 8410.401152 10040.11771 13436.81183 8137.849651 7235.755524 6865.255331 1.08182649 1.146973733 1.11060331 1.189927738 1.225067495 1.462453649 1.957219532 1.185367369 1.053967431 1 12.74509766 -5.431057127 1.693283239 1.059271546 1.593760922 0.532207501 0.182528594 0.177582296 0.984145389 0.025241213 0.075012683 3.71E-06 5.431057127 0.534489376 DAT(ph)PPVS(ph)PINMEDQER ddPTM_HeLa_Curcumin_4h_R1 2 DATPPVSPINMEDQER 16 0 P17275 P17275 JUNB Transcription factor jun-B 2 0 DAT(1)PPVS(1)PINMEDQER;DAT(1)PPVS(1)PINMEDQER ; 133.9 0.0019766 25070000 4506.1 3260.9 3574.4 3091.8 3710.5 4419.4 3732.1 3498.5 3985 3439.8 TRUE FALSE FALSE 4149.43743 3542.757666 3706.870408 3079.006951 3666.254711 3502.766623 3836.812682 4565.176545 3547.85547 3559.332794 1.165790801 0.995343192 1.041450919 0.865051719 1.030039876 0.984107648 1.077958399 1.282593342 0.996775428 1 11.79739111 -2.229886033 0.003621652 0.202463178 1.955689911 0.010722798 0.106780898 589149.3883 207.0587887 48020.68008 52300.0175 0.005889982 2.229886033 1.753226733 DAT(ph)PPVSPINMEDQER ddPTM_HeLa_Curcumin_4h_R1 2 DATPPVSPINMEDQER 16 0 P17275 P17275 JUNB Transcription factor jun-B 1 0 DAT(1)PPVSPINMEDQER;DAT(1)PPVSPINMEDQER ; 183.76 2.69E-05 24675000 5423.4 4215 4992.8 5342.4 4996.6 5244.6 4616.3 2681.31 5459.4 4316.1 TRUE FALSE FALSE 4994.132167 4579.325818 5177.83756 5320.294564 4937.018808 4156.810841 4745.820954 3498.829076 4860.517479 4466.084154 1.118235124 1.025355918 1.159368561 1.19126608 1.105446883 0.930750675 1.06263581 0.783422111 1.088317486 1 12.12479472 -3.625531433 1.221299036 1.071394284 2.67E-17 0.591491268 0.072745883 3.737725312 1.537829532 0.011872935 7.414765247 0.000236847 3.625531433 -1.071394284 DATNVGDEGGFAPNILENKEGLELLK ddPTM_HeLa_Curcumin_4h_R1 2 DATNVGDEGGFAPNILENKEGLELLK 26 1 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 0 ; ; 169.33 3.75E-12 49080000 4030.9 3139.6 3057.1 3532.2 2651.2 5225.5 3993.3 4338.5 4066.1 3100.3 FALSE FALSE TRUE 3711.850012 3410.973034 3170.398815 3517.584692 2619.586172 4141.672396 4105.341251 5661.288678 3620.059003 3208.035194 1.157047784 1.063259231 0.98826809 1.096491927 0.816570272 1.291030848 1.279705802 1.764721499 1.12843494 1 11.64747425 -4.154132729 1.300615744 1.058066238 2.192739746 0.798053341 0.108654382 0.560140174 0.676413071 0.015950561 0.896736831 7.01E-05 4.154132729 1.134673509 DAVAHCHEAER ddPTM_HeLa_Curcumin_4h_R1 1 DAVAHCHEAER 11 0 P49792;J3KQ37;Q99666;O14715;F8W705;Q99666-2;H0YBN8 P49792 RANBP2;RGPD8;RGPD5 E3 SUMO-protein ligase RanBP2;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8 0 0 108.9 0.002074 934770 646.12 516.33 610.98 362.81 306.83 420.62 361.17 331.03 425.39 389.72 FALSE FALSE TRUE 594.9789202 560.9592645 633.6234563 361.3087884 303.1712526 333.3786706 371.3034582 431.9595231 378.7257813 403.262741 1.475412578 1.391051559 1.571242249 0.895963727 0.751795844 0.826703379 0.920748238 1.071161501 0.939153913 1 8.655576305 -6.157418306 9.862808001 1.268907229 0.88204556 0.484635596 0.196819356 0.322087978 28.61424268 0.033955572 0.05635559 6.96E-07 6.157418306 -0.386861669 DAVLLVFANK ddPTM_HeLa_Curcumin_4h_R1 2 DAVLLVFANK 10 0 F5H423;P84077;P61204;C9J1Z8;P61204-2;P84085 F5H423 ARF1;ARF3;ARF5 ADP-ribosylation factor 1;ADP-ribosylation factor 3;ADP-ribosylation factor 5 0 0 ; ; 155.07 2.60E-16 752210 1099.66 908.61 1021.12 907.01 821.68 741.99 730.74 803.96 841.61 745.37 FALSE FALSE TRUE 1012.620751 987.1461997 1058.963605 903.2570329 811.8820027 588.09291 751.2425977 1049.083703 749.2874886 771.271552 1.312923766 1.279894477 1.373010067 1.171127122 1.052653894 0.762497863 0.974031255 1.360200179 0.971496338 1 9.591095089 -5.712442298 4.719560751 1.182667235 1.009602695 0.133747801 0.180685441 0.30923853 14.6888878 0.028443989 0.05712751 1.94E-06 5.712442298 -0.17306454 DAVTYTEHAK ddPTM_HeLa_Curcumin_4h_R1 1 DAVTYTEHAK 10 0 P62805 P62805 HIST1H4A Histone H4 0 0 133.81 0.0019007 11663000 5995.7 4952.8 6039.1 8833.2 6346.6 13916 8821.6 5216.3 7325.1 5252.9 FALSE FALSE TRUE 5521.134018 5380.897963 6262.914359 8796.650559 6270.92094 11029.66473 9069.110354 6806.725857 6521.554856 5435.437884 1.015766188 0.989965864 1.152237316 1.618388573 1.153710349 2.029213647 1.668515131 1.252286569 1.19982143 1 12.40818055 -6.342536326 1.762376504 1.00274308 1.578476767 0.495233431 0.234642685 0.181623475 1.104077008 0.034778356 0.06004225 4.54E-07 6.342536326 0.575733687 DAWGRLPVDLAEELGHR ddPTM_HeLa_Curcumin_4h_R1 2 DAWGRLPVDLAEELGHR 17 1 J3QRG6;P42771;P42771-4;K7ES20;K7ENC6;P42771-2 J3QRG6 CDKN2A Cyclin-dependent kinase inhibitor 2A 0 0 ; ; 141.06 0.0001557 30061300 15263 9669.6 9860 10861 6568.2 19260.9 10288.9 9916 21325.7 17797.6 FALSE FALSE TRUE 14054.91744 10505.39714 10225.42027 10816.06006 6489.878505 15265.97222 10577.57884 12939.34275 18986.32406 18416.06528 0.76318786 0.570447432 0.555244572 0.587316557 0.352403101 0.828948638 0.574366928 0.70261169 1.030965289 1 14.16867723 -8.016883068 0.809267388 0.96408044 0.590482915 0.640291837 0.121009609 0.248565795 0.353901409 0.038644434 0.028259322 9.62E-09 8.016883068 -0.373597525 DCCVEPGTELS(ph)PTLPHQL ddPTM_HeLa_Curcumin_4h_R1 2 DCCVEPGTELSPTLPHQL 18 0 Q14012 Q14012 CAMK1 Calcium/calmodulin-dependent protein kinase type 1 1 0 DCCVEPGT(0.112)ELS(0.881)PT(0.007)LPHQL;DCCVEPGT(0.003)ELS(0.955)PT(0.042)LPHQL ; 178.22 9.00E-07 31790000 2773.8 2374.6 2600 2721.9 2596 3860.7 2506.8 3078.4 2956 2752.7 TRUE FALSE FALSE 2554.250803 2579.849843 2696.358287 2710.637499 2565.044396 3059.947301 2577.134061 4016.989989 2631.734196 2848.35612 0.896745595 0.905732898 0.946636647 0.951649788 0.900535006 1.074285367 0.904779442 1.410283623 0.923948441 1 11.47591382 -4.258041575 24.89991977 0.949518628 1.410283806 0.874729913 0.052806225 81.3363039 596022.6504 0.007682216 0.074665827 5.52E-05 4.258041575 0.460765178 DCDPGS(ph)PRR ddPTM_HeLa_Curcumin_4h_R1 1 DCDPGSPRR 9 1 Q00341;Q00341-2;A0A024R4E5;H0Y394 Q00341 HDLBP Vigilin 1 0 DCDPGS(1)PRR 91.701 0.0084343 11888000 8893.5 10330 8995.9 7845.2 8377.4 9176.9 5057.6 5042.3 8096.1 7986.2 TRUE FALSE FALSE 8189.570091 11222.87917 9329.295968 7812.738641 8277.504976 7273.507495 5199.502644 6579.674058 7207.978085 8263.719856 0.991027072 1.358090469 1.128946302 0.945426367 1.00166815 0.880173532 0.629196383 0.796212138 0.872243761 1 13.01257563 -5.061681418 2.491097589 1.03143002 0.711945053 0.505457607 0.130024753 0.179496689 2.164491474 0.018356195 0.062005902 8.68E-06 5.061681418 -0.319484968 DCDVQGLEHDMEEINAR ddPTM_HeLa_Curcumin_4h_R1 1 DCDVQGLEHDMEEINAR 17 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;A0A0A6YYJ5 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 0 0 84.829 0.0068111 0 606.46 570.98 519.2 626.54 554.84 623.89 568.26 370.28 553.22 623.61 FALSE FALSE TRUE 558.4580511 620.332967 538.4420087 623.9475435 548.2238954 494.4881813 584.2038462 483.1766674 492.5331501 645.2804011 0.865450198 0.961338615 0.834431059 0.966940174 0.849590185 0.766315203 0.905348815 0.748785592 0.763285464 1 9.333782397 -13.52287875 0.047711285 1.601571169 0.540328776 0 0.091682362 295.7865273 1.120132845 24.0098875 6.3089473 3.00E-14 13.52287875 -1.061242393 DCEQAENWMAAR ddPTM_HeLa_Curcumin_4h_R1 2 DCEQAENWMAAR 12 0 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 ; ; 125.68 0.015616 62821000 2582 2821.8 2653.9 3504.8 2804.3 1611.46 1526.76 1149.8 3354 3463.6 FALSE FALSE TRUE 2377.631975 3065.703818 2752.255869 3490.298066 2770.860554 1277.225031 1569.596777 1500.368727 2986.074591 3583.959842 0.663409212 0.855395695 0.767937139 0.973866399 0.773128237 0.356372584 0.437950436 0.418634358 0.833177469 1 11.80733876 -5.326075106 4.865432729 0.841427753 0.40732083 0.822882526 0.092536762 0.088998279 4.216938276 0.018872229 0.043818381 4.72E-06 5.326075106 -0.434106923 DCGEYAHTR ddPTM_HeLa_Curcumin_4h_R1 1 DCGEYAHTR 9 0 Q9Y399;Q5T8A0 Q9Y399 MRPS2 "28S ribosomal protein S2, mitochondrial" 0 0 99.973 0.010493 1337500 436.59 500.17 584.88 679.87 624.13 665.99 382.93 260.76 411.2 452.87 FALSE FALSE TRUE 402.0334408 543.4024661 606.5561673 677.0568781 616.6876574 527.8561667 393.6739852 340.2645236 366.0923888 468.6071988 0.857932703 1.159611861 1.294380814 1.444828163 1.316001246 1.126436316 0.840093763 0.726118857 0.781235094 1 8.872235307 -7.250803808 23.60585408 0.932912666 1.144005915 0.214720568 0.210561693 470.1540933 1043514.989 0.037975176 0.04621805 5.61E-08 7.250803808 0.21109325 DCLIEDS(ph)DDEAGQS ddPTM_HeLa_Curcumin_4h_R1 2 DCLIEDSDDEAGQS 14 0 H3BPG4;H3BSW6;Q2VPK5-3;Q2VPK5 H3BPG4 CTU2 Cytoplasmic tRNA 2-thiolation protein 2 1 0 DCLIEDS(0.714)DDEAGQS(0.286);DCLIEDS(1)DDEAGQS ; 178.22 0.00015809 26376000 6957.3 5521.4 5567.5 6270.4 5806.3 7283.5 4851.7 3502.14 6398.4 5662.7 TRUE FALSE FALSE 6406.622364 5998.645213 5773.836448 6244.454746 5737.063665 5772.819998 4987.825644 4569.926364 5696.511528 5859.478404 1.093377588 1.023750716 0.985384031 1.06570147 0.979108253 0.98521056 0.851240554 0.779920336 0.972187477 1 12.51655653 -4.511697627 0.993211283 1.040378341 0.692148332 0.8031468 0.039393077 0.399205964 0.393713635 0.006378351 0.134049401 3.08E-05 4.511697627 -0.348230009 DCNDTLEEENTNLET(ph)PTKR ddPTM_HeLa_Curcumin_4h_R1 2 DCNDTLEEENTNLETPTKR 19 1 A0A087WY59;Q9BZE2 A0A087WY59 PUS3 tRNA pseudouridine synthase;tRNA pseudouridine(38/39) synthase 1 0 DCNDTLEEENT(0.003)NLET(0.978)PT(0.019)KR;DCNDTLEEENT(0.01)NLET(0.9)PT(0.09)KR ; 93.34 0.00083865 44530000 6590.8 5348.6 4916.9 5857.5 6278.9 3444.6 4577.8 4165 6426.2 5669.2 TRUE FALSE FALSE 6069.131225 5810.909151 5099.124639 5833.263217 6204.028218 2730.151131 4706.240747 5434.889327 5721.261938 5866.204278 1.034592547 0.990573951 0.869237483 0.994384604 1.057588165 0.465403351 0.802263359 0.926474611 0.975291972 1 12.5182116 -5.302342571 24.99999156 1.004081066 0.738468404 0.500553888 0.117080924 271.4988451 165939.4237 0.015958508 0.035684655 4.98E-06 5.302342571 -0.265612662 DCS(ph)PTCWEQGK ddPTM_HeLa_Curcumin_4h_R1 1 DCSPTCWEQGK 11 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 0 DCS(0.856)PT(0.144)CWEQGK 126.34 0.0033732 13298000 5974.3 5260.2 6012.3 6426 5815.4 4264.9 3718.4 2373.1 7002.7 5483.5 TRUE FALSE FALSE 5501.427851 5714.868249 6235.121127 6399.410915 5746.055153 3380.311665 3822.728296 3096.647266 6234.52133 5674.051217 0.969576699 1.007193631 1.098883476 1.12783806 1.01269004 0.595749234 0.673721147 0.545755959 1.098777768 1 12.47016346 -5.262465669 24.98589065 1.008194454 0.611939998 0.906796012 0.063861963 20.24533093 492898.0082 0.009165598 0.02165168 5.46E-06 5.262465669 -0.396254457 DDAMLLK(ac)GK ddPTM_HeLa_Curcumin_4h_R1 2 DDAMLLKGK 9 1 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 1 ; DDAMLLK(1)GK;DDAMLLK(1)GK 129.1 0.00066292 2060400 4320.5 4018.4 4055.3 4533.3 6452.1 5646.3 4732.6 4190.6 6034 3671.7 FALSE TRUE FALSE 3978.527866 4365.73259 4205.592985 4514.542406 6375.162922 4475.193733 4865.384019 5468.294649 5372.085296 3799.291302 1.047176315 1.149091302 1.10694144 1.188259085 1.677987397 1.17790224 1.280603047 1.439293335 1.413970362 1 11.89151462 -6.100666086 3.300056437 1.039691119 1.375016556 0.207480955 0.175827359 0.12876666 2.656318869 0.019237709 0.033659783 7.93E-07 6.100666086 0.335325437 DDAT(ph)PVRDEPMDAESITFK ddPTM_HeLa_Curcumin_4h_R1 2 DDATPVRDEPMDAESITFK 19 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 0 DDAT(1)PVRDEPMDAESITFK;DDAT(1)PVRDEPMDAESITFK ; 94.61 0.0012197 23798800 4634 4412.3 4676.2 4237.1 5060.3 4963.1 4684.2 4673.1 4626.8 4085.9 TRUE FALSE FALSE 4267.21401 4793.679551 4849.504086 4219.568003 4999.959227 3933.697114 4815.626045 6097.906678 4119.251616 4227.884721 1.009302356 1.133824564 1.147028456 0.998032889 1.182614843 0.930417307 1.139015456 1.442306752 0.974305566 1 12.04572032 -4.316999273 3.093436429 1.032100187 1.481425713 0.683891222 0.079883287 0.124148263 1.855967225 0.010861068 0.125413625 4.82E-05 4.316999273 0.449325526 DDATLSGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 DDATLSGKR 9 1 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 0 1 ; DDATLSGK(1)R;DDATLSGK(1)R 177.7 1.01E-16 156665000 9118.7 8410.2 9184.4 7585.2 8098.3 10927.2 6082.5 7966.9 8257.4 7769.1 FALSE TRUE FALSE 8396.945273 9137.140213 9524.781943 7553.814452 8001.733062 8660.775545 6253.15858 10395.97113 7351.583879 8039.075647 1.044516266 1.136590899 1.184810588 0.93963719 0.995354866 1.077334749 0.777845471 1.293179912 0.914481242 1 12.97281391 -4.200858488 22.59770291 1.024495717 1.29318766 0.365167744 0.110927322 23353.56553 8710162.078 0.01363254 40.73115598 6.30E-05 4.200858488 0.268691943 DDDDIDLFGS(ph)DDEEESEEAKR ddPTM_HeLa_Curcumin_4h_R1 4 DDDDIDLFGSDDEEESEEAKR 21 1 P24534;C9JZW3 P24534 EEF1B2 Elongation factor 1-beta 1 0 DDDDIDLFGS(1)DDEEESEEAKR;DDDDIDLFGS(1)DDEEESEEAKR;DDDDIDLFGS(1)DDEEESEEAKR;DDDDIDLFGS(1)DDEEESEEAKR ;;; 112.41 1.27E-05 244515800 8872.2 9116.9 9689.1 8807.8 10465.8 9828.8 9672.2 9351 8342.4 8560.3 TRUE FALSE FALSE 8169.956008 9904.924212 10048.18657 8771.355657 10341.00217 7790.196087 9943.575901 12202.07685 7427.259592 8857.769788 0.922349102 1.118218745 1.134392382 0.990244256 1.167449868 0.879476016 1.122582336 1.377556331 0.838502216 1 13.11272779 -4.360741787 3.112646993 0.9977619 1.398812323 0.534613132 0.104366376 0.154170231 2.353298409 0.013369235 0.130256246 4.36E-05 4.360741787 0.401050423 DDDKNNDGYIDYAEFAK ddPTM_HeLa_Curcumin_4h_R1 2 DDDKNNDGYIDYAEFAK 17 1 Q8NI22-2;Q8NI22-3;Q8NI22 Q8NI22-2 MCFD2 Multiple coagulation factor deficiency protein 2 0 0 ; ; 111.33 0.00077336 4695300 3619 2687.6 3787 3482.8 4001.2 4107.7 3471.7 4617.4 3471.1 2822.2 FALSE FALSE TRUE 3332.552331 2919.904168 3927.349551 3468.389096 3953.488303 3255.716717 3569.106558 6025.224004 3090.329014 2920.27124 1.14117904 0.999874302 1.344857799 1.18769416 1.353808595 1.114867918 1.222183237 2.063241223 1.058233554 1 11.51188666 -2.093265329 1.212971874 1.107130098 199.9999983 0.820525941 0.125509536 97.7478017 0.886880198 0.020274083 53302.09226 0.00806742 2.093265329 198.8928682 up DDDVPLDWR ddPTM_HeLa_Curcumin_4h_R1 1 DDDVPLDWR 9 0 O95340;O95340-2 O95340 PAPSS2 Bifunctional 3-phosphoadenosine 5-phosphosulfate synthase 2;Sulfate adenylyltransferase;Adenylyl-sulfate kinase 0 0 180.45 0.011923 23094000 4740.5 4307.1 4283.7 4020.6 4583.3 8194.6 5200.7 5594.2 4116.9 4103.4 FALSE FALSE TRUE 4365.284423 4679.386532 4442.45769 4003.963823 4528.647141 6494.947588 5346.617645 7299.845827 3665.28637 4245.992845 1.028095096 1.102071224 1.046270649 0.94299825 1.066569659 1.529665222 1.259214945 1.719231778 0.863234231 1 12.05188622 -5.30188301 5.557834891 1.019418429 1.479168483 0.776054134 0.121780196 0.057304937 4.734525128 0.014114686 0.032707141 4.99E-06 5.30188301 0.459750053 DDEENYLDLFSHK ddPTM_HeLa_Curcumin_4h_R1 1 DDEENYLDLFSHK 13 0 Q07666-2;Q07666;Q07666-3 Q07666-2 KHDRBS1 "KH domain-containing, RNA-binding, signal transduction-associated protein 1" 0 0 140.82 0.000223 0 1246.7 1271.1 1101.1 1455.2 1145.5 1227.6 1014.5 1114.8 1321.8 1193.3 FALSE FALSE TRUE 1148.022379 1380.96822 1141.907735 1449.178768 1131.840661 972.9819221 1042.96414 1454.697388 1176.801847 1234.767086 0.929748122 1.118403815 0.924796059 1.173645446 0.916643044 0.787988223 0.844664675 1.178114808 0.95305573 1 10.27002322 -4.237754787 23.82568849 0.965922779 1.178115272 0.260986572 0.109324626 3995.843718 4019531.502 0.014926376 1.114170467 5.78E-05 4.237754787 0.212192493 DDEKEAEEGEDDRDS(ph)ANGEDDS ddPTM_HeLa_Curcumin_4h_R1 1 DDEKEAEEGEDDRDSANGEDDS 22 2 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;P07910-3;G3V2D6 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 0 DDEKEAEEGEDDRDS(0.542)ANGEDDS(0.458) 75.404 0.0010699 24530000 4138.7 3945.1 4483.1 3303.7 5069.6 4150.3 3688 3480 3051.6 3324.6 TRUE FALSE FALSE 3811.117528 4286.096865 4649.24763 3290.030165 5009.148331 3289.480996 3791.475354 4541.03598 2716.847115 3440.129603 1.107841264 1.245911451 1.351474557 0.956368086 1.456092912 0.95620845 1.102131545 1.320018867 0.789751384 1 11.7482472 -7.94664032 1.213517971 1.025965581 1.189104838 0.262398432 0.171595261 0.4888587 1.506273113 0.0355072 0.03041059 1.13E-08 7.94664032 0.163139257 DDFHWEEYLK ddPTM_HeLa_Curcumin_4h_R1 2 DDFHWEEYLK 10 0 Q9UQR0 Q9UQR0 SCML2 Sex comb on midleg-like protein 2 0 0 ; ; 99.568 0.010268 3798600 5729.2 5358.2 6181.9 5861.5 5618.7 6815.4 5449 3257.5 6253.1 5799.6 FALSE FALSE TRUE 5275.727775 5821.338932 6411.006652 5837.246666 5551.700672 5401.809215 5601.884275 4250.696754 5567.150574 6001.135668 0.879121564 0.970039548 1.068298903 0.972690335 0.925108343 0.900131161 0.933470694 0.70831539 0.927682839 1 12.55101983 -3.655017481 1.355845133 0.952980183 7.52E-12 0.674472062 0.051062032 3.23182396 1.608417708 0.009056507 6.352324548 0.000221301 3.655017481 -0.952980183 DDFNSGFRDDFLGGR ddPTM_HeLa_Curcumin_4h_R1 2 DDFNSGFRDDFLGGR 15 1 Q15056 Q15056 EIF4H Eukaryotic translation initiation factor 4H 0 0 ; ; 102.9 0.0025688 16880200 3743.1 2998.6 3182.8 3757 3295.9 3864.8 2663.2 2310.46 3909.2 3326.4 FALSE FALSE TRUE 3446.829685 3257.785622 3300.757368 3741.454529 3256.598545 3063.196915 2737.922224 3014.908618 3480.37054 3441.992152 1.001405446 0.946482583 0.958967139 1.087002632 0.946137702 0.889948838 0.795446969 0.875919666 1.011150051 1 11.74902809 -5.244795825 2.589737647 0.998262428 0.838199971 0.716992622 0.041455348 0.10226347 1.343842785 0.005599489 0.015974557 5.69E-06 5.244795825 -0.160062456 DDGELGGNFLHSFQNDNYSPS(ph)MTMSV ddPTM_HeLa_Curcumin_4h_R1 1 DDGELGGNFLHSFQNDNYSPSMTMSV 26 0 Q9NW25;Q9BWW4-2;Q9BWW4-3;Q9BWW4 Q9NW25 SSBP3 Single-stranded DNA-binding protein 3 1 0 DDGELGGNFLHS(0.001)FQNDNY(0.087)S(0.087)PS(0.275)MT(0.275)MS(0.275)V 57.802 0.00302 0 1027.6 827.89 769.3 795.89 976.78 941.51 799.02 449.47 866.16 842.58 TRUE FALSE FALSE 946.2643757 899.4491226 797.8109347 792.5968181 965.1325365 746.230213 821.4383507 586.5113339 771.144415 871.8595923 1.085340328 1.031644465 0.915068139 0.909087685 1.106981611 0.855906409 0.942168163 0.67271306 0.884482343 1 9.767952006 -3.449432568 0.648185263 1.029940313 6.37E-20 0.469396994 0.087466329 3.726160293 0.508485977 0.012974216 3.634782402 0.000355277 3.449432568 -1.029940313 DDGELGGNFLHSFQNDNYSPSMTMS(ph)V ddPTM_HeLa_Curcumin_4h_R1 1 DDGELGGNFLHSFQNDNYSPSMTMSV 26 0 Q9NW25;Q9BWW4-2;Q9BWW4-3;Q9BWW4 Q9NW25 SSBP3 Single-stranded DNA-binding protein 3 1 0 DDGELGGNFLHS(0.001)FQNDNY(0.024)S(0.027)PS(0.073)MT(0.2)MS(0.675)V 57.216 0.00246 6858900 1723.1 1335.7 1726.7 1925.7 1812.5 1595.6 1205.1 772.04 2101.5 1898.6 TRUE FALSE FALSE 1586.714817 1451.151956 1790.693021 1917.731964 1790.887121 1264.654574 1238.911863 1007.431442 1870.970708 1964.576209 0.807662645 0.73865903 0.911490739 0.976155547 0.911589539 0.643728947 0.630625504 0.512798352 0.952353337 1 10.94000242 -5.172898499 3.375692603 0.90000778 0.582330021 0.76230305 0.078282828 0.112430024 2.440888428 0.014001657 0.039112708 6.72E-06 5.172898499 -0.317677759 DDGLFSGDPNWFPK ddPTM_HeLa_Curcumin_4h_R1 2 DDGLFSGDPNWFPK 14 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 0 ; ; 172.13 2.32E-32 60321000 3910.59 2700.5 3961.9 3148.5 3505.7 5488.266 4025.5 3486 3313.2 3167.8 FALSE FALSE TRUE 3601.062675 2933.919187 4108.731499 3135.472341 3463.896817 4349.937766 4138.444696 4548.865352 2949.750249 3277.880814 1.098594757 0.895065853 1.253471902 0.956554713 1.056748861 1.327057942 1.26253666 1.387745806 0.899895517 1 11.67854768 -5.269881507 7.503805175 1.045340139 1.319902192 0.63666154 0.103866197 0.060091982 25.76683781 0.012394481 0.029178095 5.37E-06 5.269881507 0.274562053 DDGLFSGDPNWFPKK ddPTM_HeLa_Curcumin_4h_R1 3 DDGLFSGDPNWFPKK 15 1 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 0 ;; ;; 106.6 0.0037928 111283600 12650.7 9704.1 11598.6 11702.7 10341.9 14940.7 12297.7 11285.73 12677.8 10332.62 FALSE FALSE TRUE 11649.38375 10542.87916 12028.45432 11654.27733 10218.5796 11841.8304 12642.74036 14726.69712 11287.07706 10691.67778 1.0895749 0.986082763 1.125029633 1.0900326 0.955750801 1.107574569 1.18248423 1.377398144 1.055688106 1 13.38420064 -4.350334221 1.557384688 1.04384281 1.466021402 0.802167393 0.050771919 0.29904906 0.764319702 0.007773909 0.181752194 4.46E-05 4.350334221 0.422178592 DDGSWEVIEGYR ddPTM_HeLa_Curcumin_4h_R1 2 DDGSWEVIEGYR 12 0 P49448;P00367 P49448 GLUD2;GLUD1 "Glutamate dehydrogenase 2, mitochondrial;Glutamate dehydrogenase 1, mitochondrial" 0 0 ; ; 238.51 2.58E-25 58685000 3149.8 2723.5 2832 2872.1 2900.1 4552.8 3122.8 2777.3 3244.4 2603.3 FALSE FALSE TRUE 2900.490006 2958.907204 2936.956411 2860.216011 2865.518202 3608.497959 3210.417363 3624.085985 2888.497437 2693.764481 1.076742242 1.098428324 1.090279582 1.061791419 1.063759739 1.339574408 1.191795863 1.345361115 1.072290268 1 11.395408 -1 0.263830051 1.014461312 3.293663034 0.696907625 0.062442265 17.28328354 0.218292982 0.028839635 18.02541054 0.1 1 2.279201721 DDGVFVQEVTQNS(ph)PAAR ddPTM_HeLa_Curcumin_4h_R1 4 DDGVFVQEVTQNSPAAR 17 0 Q09666;E9PKR9;E9PLK4;E9PJZ0;E9PJC6;Q09666-2;E9PQE3 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 DDGVFVQEVT(0.004)QNS(0.996)PAAR;DDGVFVQEVTQNS(1)PAAR;DDGVFVQEVTQNS(1)PAAR;DDGVFVQEVTQNS(1)PAAR ;;; 264.01 4.89E-52 954830000 16187.9 14949.5 14780.1 15649.1 15123.1 27847.8 25835.5 16237.4 17953.1 11023.2 TRUE FALSE FALSE 14906.61063 16241.66817 15327.86351 15584.34817 14942.76691 22071.85237 26560.3746 21188.10851 15983.68985 11406.25538 1.306880316 1.423926401 1.343812057 1.366298373 1.31005018 1.935065597 2.328579688 1.85758672 1.401309134 1 13.47753762 -2.758596377 0.23900133 1.021257699 4.412910203 0.630193136 0.22569172 7.669375219 0.195541864 0.137367147 8.730742169 0.001743426 2.758596377 3.391652504 DDILNGSHPVSFDK ddPTM_HeLa_Curcumin_4h_R1 2 DDILNGSHPVSFDK 14 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 ; ; 132.31 0.00081137 20885800 4781.7 3884.1 3973.1 3908.4 4518.4 6897.2 4907.1 4577.5 4931.3 4132.8 FALSE FALSE TRUE 4403.223399 4219.824297 4120.346581 3892.228076 4464.521031 5466.642973 5044.780019 5973.158678 4390.348728 4276.414492 1.029653091 0.986766906 0.963504962 0.910161558 1.043986975 1.278323928 1.179675176 1.396767944 1.026642468 1 12.06218598 -5.303852311 4.080012408 1.000612193 1.277255826 0.833845823 0.059598031 0.063695487 2.316335173 0.008228344 0.019938263 4.97E-06 5.303852311 0.276643633 DDISEIQSLAS(ph)DHS(ph)GR ddPTM_HeLa_Curcumin_4h_R1 1 DDISEIQSLASDHSGR 16 0 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 2 0 DDISEIQSLAS(1)DHS(1)GR 102.39 0.0049078 2487800 2250.7 2075 2267.4 2290.2 2847.3 2477.1 1857.9 1924.5 1878 1926.4 TRUE FALSE FALSE 2072.55472 2254.353754 2351.431839 2280.723759 2813.347807 1963.321537 1910.027674 2511.271191 1671.988099 1993.342257 1.039738516 1.130941637 1.179642799 1.144170677 1.41137218 0.984939506 0.958203574 1.259829406 0.838786261 1 10.96097373 -7.298749898 2.462362987 1.01598034 1.151412403 0.282438382 0.13304557 0.34834491 4.016003268 0.021727922 0.025389018 5.03E-08 7.298749898 0.135432063 DDNMFQIGK ddPTM_HeLa_Curcumin_4h_R1 3 DDNMFQIGK 9 0 P53999 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 0 0 ;; ;; 164.96 0.0025505 162158100 3486.23 3028.43 2836.84 3260.6 2979.78 3422.69 3102.77 3458.5 3117.12 2864.56 FALSE FALSE TRUE 3210.291217 3290.193995 2941.975786 3247.108501 2944.24807 2712.785512 3189.825376 4512.980729 2775.179735 2964.103247 1.083056476 1.110013289 0.992534855 1.095477529 0.993301456 0.915212895 1.076151912 1.522545051 0.936262844 1 11.53337999 -4.267370194 4.633855792 1.034644274 1.550324523 0.847655839 0.063636972 0.046727142 2.669487968 0.008110954 0.077320413 5.40E-05 4.267370194 0.515680249 DDNMFQIGK(ac)MR ddPTM_HeLa_Curcumin_4h_R1 2 DDNMFQIGKMR 11 1 P53999 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 0 1 ; DDNMFQIGK(1)MR;DDNMFQIGK(1)MR 143.5 2.10E-05 5469300 1401.87 1165.55 1330.65 1351.4 1259.66 2177.89 1683.36 1594.08 1561.12 1048.12 FALSE TRUE FALSE 1290.91051 1266.294948 1379.96506 1345.808265 1244.639377 1726.171064 1730.590551 2080.107654 1389.869042 1084.542092 1.190281613 1.16758488 1.272394193 1.240899984 1.147617401 1.591612789 1.595687769 1.917959357 1.281526141 1 10.08287033 -1 0.323054182 1.061303911 9.622530815 0.830961212 0.107628744 10.77991429 0.137272019 0.029904129 55.46310322 0.1 1 8.561226904 DDPDGKQEAKPQQAAGMLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 DDPDGKQEAKPQQAAGMLSPK 21 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 DDPDGKQEAKPQQAAGMLS(1)PK 42.791 0.016886 27252000 3149.4 2432.3 3307.2 3111.2 3798.3 3076.5 3173.2 1169.3 2604.5 2555.9 TRUE FALSE FALSE 2900.121667 2642.537174 3429.767741 3098.326679 3753.007753 2438.399221 3262.231452 1525.814187 2318.792866 2644.717335 1.096571505 0.999175654 1.296837169 1.171515246 1.419058175 0.921988595 1.233489647 0.576929023 0.876763969 1 11.36889782 -4.251738887 24.63706972 1.094550923 0.576928682 0.489234406 0.163309983 683.2722791 1735314.548 0.020504667 0.357041938 5.60E-05 4.251738887 -0.51762224 DDREDLVYQAK ddPTM_HeLa_Curcumin_4h_R1 1 DDREDLVYQAK 11 1 P62258;B4DJF2;I3L3T1;I3L0W5 P62258 YWHAE 14-3-3 protein epsilon 0 0 121.9 0.003408 18958000 3340.1 2961.9 2744.6 2583.1 2846 2389.6 2714.5 2343.2 2914.7 2534.9 FALSE FALSE TRUE 3075.727561 3217.913438 2846.31729 2572.411817 2812.063309 1893.970024 2790.661564 3057.630893 2594.964702 2622.987586 1.172604696 1.226812302 1.085143256 0.980718258 1.072084109 0.72206595 1.063924808 1.165705438 0.989316425 1 11.35699526 -6.298572292 6.291806186 1.097248972 0.992814245 0.120603164 0.12584025 0.333586091 39.89676106 0.020206809 0.031304032 5.03E-07 6.298572292 -0.104434727 TGSVQTPPDLES(ph)SEEVDAAEGAPEVVGPK ddPTM_HeLa_Curcumin_4h_R1 2 TGSVQTPPDLESSEEVDAAEGAPEVVGPK 29 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7;H7BZ26 E9PHV5 SSFA2 Sperm-specific antigen 2 1 0 TGSVQT(0.004)PPDLES(0.746)S(0.249)EEVDAAEGAPEVVGPK;TGSVQT(0.001)PPDLES(0.499)S(0.499)EEVDAAEGAPEVVGPK ; 60.993 0.00092164 20239600 9791.5 7757.4 9144.9 9944.9 9841.2 8666.5 2581.25 1348.81 9887.9 8663.8 TRUE FALSE FALSE 9016.492443 8427.91509 9483.818039 9903.750639 9723.850117 6868.970208 2653.672928 1760.05596 8803.222108 8964.866405 1.005758707 0.940104928 1.057887269 1.104729306 1.084662022 0.766209991 0.296008084 0.196328186 0.981969135 1 13.13006637 -4.843906909 2.570729851 1.01426715 0.203562484 0.974510655 0.049883594 0.030506834 0.395625088 0.007551405 0.031888191 1.43E-05 4.843906909 -0.810704666 down NSGS(ph)DGSPSPLLAR ddPTM_HeLa_Curcumin_4h_R1 1 NSGSDGSPSPLLAR 14 0 H7C1V4;Q9HCH0-2;Q9HCH0 H7C1V4 NCKAP5L Nck-associated protein 5-like 1 0 NS(0.283)GS(0.433)DGS(0.283)PSPLLAR 122.16 0.0018493 0 1778.7 1694.9 1731.8 1836.3 1632.1 1698.7 889.67 540.92 1962.5 1635 TRUE FALSE FALSE 1637.914018 1841.399604 1795.982031 1828.701877 1612.638273 1346.370472 914.6317458 705.8440179 1747.21866 1691.816128 0.968139499 1.088415918 1.061570463 1.080910535 0.953199492 0.795813711 0.540621247 0.417210834 1.032747372 1 10.72435707 -4.843267251 1.661866085 1.005882151 0.407071586 0.961630192 0.043894464 0.068224434 0.332575639 0.00760534 0.045761322 1.43E-05 4.843267251 -0.598810565 down DDSDSTLK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 DDSDSTLKK 9 1 Q92797;M0R3C7;A0A087WUE9;Q92797-2 Q92797 SYMPK Symplekin 0 1 ; DDSDSTLK(1)K;DDSDSTLK(1)K 169.44 3.20E-12 26759000 8906.6 9524 8985.8 8885.9 7327.9 11321.4 8755.7 10997 9165.5 8858.5 FALSE TRUE FALSE 8201.633212 10347.21212 9318.821653 8849.1325 7240.519579 8973.214022 9001.361377 14349.93468 8160.067581 9166.332216 0.894756269 1.128827963 1.016635818 0.965395132 0.789903683 0.978931792 0.982002525 1.565504538 0.890221671 1 13.16212886 -4.260475014 5.214418335 0.958590115 1.592160534 0.821294257 0.084695035 0.048984557 4.509865525 0.011802719 0.110841297 5.49E-05 4.260475014 0.633570419 KPVTVSPT(ph)TPTS(ph)PTEGEAS ddPTM_HeLa_Curcumin_4h_R1 2 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 2 0 KPVT(0.009)VS(0.428)PT(0.546)T(0.016)PT(0.006)S(0.885)PT(0.103)EGEAS(0.005);KPVTVS(0.008)PT(0.755)T(0.179)PT(0.062)S(0.564)PT(0.402)EGEAS(0.03) ; 124.04 0.00028015 36589100 9084.1 7094.4 7254.8 7799.3 8794.2 13586.8 16895.6 20357.7 8520.7 8090.5 TRUE FALSE FALSE 8365.0839 7707.608324 7523.66927 7767.028563 8689.334909 10768.74453 17369.64506 26564.66901 7586.000528 8371.644273 0.999216358 0.920680343 0.898708668 0.927778141 1.037948416 1.286335656 2.074818817 3.173172217 0.906154189 1 13.03129529 -4.380479098 1.383165394 0.978082895 3.805857521 0.995463555 0.047396582 0.049240979 0.096973653 0.007725773 0.181194397 4.16E-05 4.380479098 2.827774626 up DDSHSAEDS(ph)EDEKEDHK ddPTM_HeLa_Curcumin_4h_R1 2 DDSHSAEDSEDEKEDHK 17 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 DDSHS(0.001)AEDS(0.999)EDEKEDHK;DDSHS(0.002)AEDS(0.998)EDEKEDHK ; 79.804 0.0036006 187244000 13779.5 13007.7 13528.3 12553.4 17109 15178.9 14426.8 14330.5 11529 9952.7 TRUE FALSE FALSE 12688.83803 14132.02763 14029.6707 12501.45736 16904.98635 12030.62504 14831.57718 18699.80348 10264.29754 10298.55558 1.232098806 1.372233952 1.362294992 1.213903955 1.641491004 1.168185668 1.44016091 1.815769535 0.99667351 1 13.33015439 -1 0.074981597 0.582583415 3.235162019 0.608859517 0.155334967 100.1379853 0.556295037 3.272965504 27.89171731 0.1 1 2.652578603 DDSHSAEDS(ph)EDEKEDHKNVR ddPTM_HeLa_Curcumin_4h_R1 1 DDSHSAEDSEDEKEDHKNVR 20 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 DDS(0.031)HS(0.083)AEDS(0.886)EDEKEDHKNVR 57.248 0.0060891 33775000 3364.1 2666.2 2753.3 2885.6 3312.5 3519.2 3233.5 3929.3 3338.2 3154.4 TRUE FALSE FALSE 3097.827935 2896.654448 2855.33972 2873.660152 3273.000601 2789.27825 3324.223307 5127.325482 2972.007812 3264.015165 0.949085031 0.887451283 0.874793644 0.880406495 1.002752878 0.854554317 1.018446036 1.570864479 0.910537378 1 11.67243205 -4.267961142 4.000165307 0.950043669 1.622914757 0.923497203 0.055343834 0.047604452 1.583459001 0.008336614 0.091690193 5.40E-05 4.267961142 0.672871089 RGT(ph)GQSDDSDIWDDTALIK ddPTM_HeLa_Curcumin_4h_R1 1 RGTGQSDDSDIWDDTALIK 19 1 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 0 RGT(0.45)GQS(0.45)DDS(0.1)DIWDDTALIK 69.27 0.0056387 163840000 4050.3 3172.2 3205.9 3517.3 3465.9 3419.4 1543.7 947.79 4605.3 3617.7 TRUE FALSE FALSE 3729.714481 3446.390833 3324.713474 3502.746345 3424.571406 2710.177895 1587.012067 1236.766808 4100.110112 3743.414806 0.996340153 0.920654272 0.888149897 0.935708845 0.914825523 0.723985461 0.423947692 0.330384655 1.095286076 1 11.87013921 -4.840191987 1.22325816 0.982158384 0.252394889 0.951587876 0.053087685 0.080689452 0.18113383 0.006841987 0.057069039 1.44E-05 4.840191987 -0.729763495 down DDSLDLSPQGRLS(ph)DVLK ddPTM_HeLa_Curcumin_4h_R1 1 DDSLDLSPQGRLSDVLK 17 1 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 0 DDSLDLS(0.001)PQGRLS(0.999)DVLK 61.276 0.014269 3599300 3206.7 2293.8 2679.1 3063.8 2686.2 3237.9 2112.6 1969.2 3425.3 2359 TRUE FALSE FALSE 2952.886311 2492.065851 2778.389803 3051.122807 2654.168819 2566.323041 2171.87387 2569.600015 3049.55316 2440.975074 1.20971588 1.020930479 1.138229485 1.249960657 1.087339583 1.051351596 0.889756677 1.052694082 1.249317616 1 11.25324185 -5.009664111 4.107476161 1.108409376 0.969525615 0.313607582 0.091975223 0.215346505 8.494592184 0.013777196 0.041224638 9.78E-06 5.009664111 -0.138883761 DDTIYEDEDVKEAIR ddPTM_HeLa_Curcumin_4h_R1 2 DDTIYEDEDVKEAIR 15 1 E5RHG9;B7Z2R2;P14927;P14927-2 E5RHG9 UQCRB Cytochrome b-c1 complex subunit 7 0 0 ; ; 211.82 2.11E-10 30569000 5156.9 4282.4 5651 5198.3 6069.6 9911.2 6386.3 5338.4 6219 4543.6 FALSE FALSE TRUE 4748.725923 4652.551574 5860.431031 5176.790812 5997.223984 7855.505398 6565.48239 6966.053585 5536.791259 4701.489762 1.010047063 0.989590919 1.246505114 1.101095839 1.275600775 1.670854515 1.396468507 1.481669415 1.177667407 1 12.19890226 -5.803983322 1.053761298 1.007610028 1.518394501 0.719515556 0.114319206 0.152377362 0.32898541 0.016092344 0.046829967 1.57E-06 5.803983322 0.510784473 DDWEEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 DDWEEKR 7 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 1 DDWEEK(1)R 81.548 0.016564 1751900 1703.3 1642.7 1555.5 1671.2 2165.6 2382 1786.2 1514.1 2288.4 1950.9 FALSE TRUE FALSE 1568.482008 1784.687668 1613.148198 1664.285017 2139.776634 1887.946349 1836.315965 1975.74212 2037.368245 2018.69363 0.776978728 0.884080497 0.799105013 0.824436652 1.059980872 0.935231737 0.9096556 0.978723116 1.009250842 1 10.97920626 -5.77995965 24.99988403 0.878993111 0.963975859 0.223315763 0.080381882 347.9121525 469634.2825 0.014179914 0.025736478 1.66E-06 5.77995965 0.084982748 DDYVHEFCR ddPTM_HeLa_Curcumin_4h_R1 2 DDYVHEFCR 9 0 Q13564;Q13564-4;Q13564-3;Q13564-2 Q13564 NAE1 NEDD8-activating enzyme E1 regulatory subunit 0 0 ; ; 112.3 0.0060891 4486600 8226.5 7051 7678.2 6771.2 8060.1 10285.3 7054.9 6740.7 7168.5 6670.9 FALSE FALSE TRUE 7575.363844 7660.457021 7962.760846 6743.182569 7963.988572 8152.012841 7252.841507 8795.9084 6382.133485 6902.713278 1.09744727 1.109774767 1.153569694 0.976888695 1.153747556 1.180986738 1.050723276 1.274268254 0.924583309 1 12.75294784 -1.000000001 0.017033805 3.43E-11 2.476449014 0.458607654 0.073776258 2813.161491 3.735186385 211.2380827 347.9172903 0.1 1.000000001 2.476449014 DEALQNIS(ph)ADDLPDSASQAAHPQDSAFSYR ddPTM_HeLa_Curcumin_4h_R1 2 DEALQNISADDLPDSASQAAHPQDSAFSYR 30 0 Q14C86-4;Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;F8W9S7;Q14C86-3 Q14C86-4 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 0 DEALQNIS(0.997)ADDLPDS(0.003)ASQAAHPQDSAFSYR;DEALQNIS(0.953)ADDLPDS(0.034)AS(0.012)QAAHPQDSAFSYR ; 104.57 1.29E-10 29979000 2448.33 2222.32 2436.45 2388.69 3571.9 4332.4 2333.09 1160.71 2906.97 2452.25 TRUE FALSE FALSE 2254.542097 2414.407438 2526.74698 2378.806234 3529.307425 3433.811404 2398.550226 1514.605136 2588.082664 2537.465505 0.888501575 0.951503551 0.995775893 0.937473329 1.390878977 1.353244565 0.945254318 0.596896838 1.01994792 1 11.30917249 DEDDDEEEEEEGGSWGR ddPTM_HeLa_Curcumin_4h_R1 2 DEDDDEEEEEEGGSWGR 17 0 Q5VYD6;O00165-4;O00165-6;O00165-3;O00165;O00165-2 Q5VYD6 HAX1 HCLS1-associated protein X-1 0 0 ; ; 350.9 9.71E-172 19148400 2608 1956.73 2517.1 2430.8 2761.7 2323.05 1757.83 2154.3 2135 2031 FALSE FALSE TRUE 2401.574048 2125.861022 2610.38594 2420.741994 2728.768531 1841.223244 1807.149979 2811.136153 1900.795842 2101.577099 1.142748486 1.011555095 1.242108101 1.15186923 1.29843846 0.876115011 0.859901823 1.337631703 0.904461627 1 11.03725667 -4.217935697 22.82495788 1.074492039 1.337634485 0.243864259 0.145847934 11470.42161 6017741.486 0.019061673 10.11422691 6.05E-05 4.217935697 0.263142446 DEDEGIPS(ph)ENEEEKK ddPTM_HeLa_Curcumin_4h_R1 1 DEDEGIPSENEEEKK 15 1 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 DEDEGIPS(1)ENEEEKK 73.735 0.011258 27446000 3657.1 3473.4 3636.2 3204.8 4866.8 3677.5 3053.8 2102.8 2911.6 2728.8 TRUE FALSE FALSE 3367.636676 3773.625219 3770.960771 3191.539387 4808.766589 2914.745046 3139.481409 2743.93404 2592.204764 2823.625597 1.192664027 1.336446738 1.335503112 1.130298362 1.703046818 1.032270372 1.11186179 0.971776868 0.918041247 1 11.46333309 -8.641220607 0.883700189 1.015627734 1.234601986 0.213454406 0.197366422 0.719330195 1.133857591 0.083573024 0.03993202 2.28E-09 8.641220607 0.218974252 DEDMLYS(ph)PELAQR ddPTM_HeLa_Curcumin_4h_R1 2 DEDMLYSPELAQR 13 0 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 0 DEDMLYS(1)PELAQR;DEDMLYS(1)PELAQR ; 250.05 7.40E-36 53852000 7552.4 6637.4 6991.7 6843.2 7042.8 7905 7123.1 4968.1 7046.4 6420.3 TRUE FALSE FALSE 6954.619571 7211.10728 7250.818553 6814.884652 6958.81921 6265.413892 7322.955015 6482.85082 6273.427549 6643.404947 1.04684565 1.085453519 1.091431067 1.02581202 1.047477802 0.943102813 1.102289424 0.975832554 0.94430907 1 12.69770714 -6.008276147 22.42174264 1.034273293 1.020299305 0.01787739 0.055416921 468.9615816 1270539.641 0.007306168 0.012783768 9.81E-07 6.008276147 -0.013973988 DEEDTS(ph)FESLSK ddPTM_HeLa_Curcumin_4h_R1 2 DEEDTSFESLSK 12 0 H7C3L4;E7EQA9;Q92844 H7C3L4 TANK TRAF family member-associated NF-kappa-B activator 1 0 DEEDT(0.064)S(0.936)FESLSK;DEEDT(0.059)S(0.941)FESLSK ; 227.56 7.06E-19 8868200 9222.1 7299.4 8561.5 7741 9939.3 10704.4 8137.1 5571.8 7676.9 6925.9 TRUE FALSE FALSE 8492.161054 7930.327611 8878.796721 7708.969793 9820.780339 8484.186777 8365.405126 7270.616171 6834.763277 7166.574509 1.184967943 1.106571571 1.2389178 1.075684036 1.370359064 1.183855239 1.167280842 1.014517628 0.953700163 1 12.80706799 -9.27404287 0.663183693 0.978923911 1.175729136 0.397439887 0.092423171 0.8887839 0.585099696 0.10255194 0.018828125 5.32E-10 9.27404287 0.196805225 DEEPSGWEEPS(ph)PQSISR ddPTM_HeLa_Curcumin_4h_R1 2 DEEPSGWEEPSPQSISR 17 0 H0Y720;Q9UPQ9-1;Q9UPQ9 H0Y720 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 0 DEEPSGWEEPS(0.985)PQS(0.013)IS(0.002)R;DEEPSGWEEPS(0.999)PQS(0.001)ISR ; 184.2 4.31E-06 6932800 3171.65 2153.47 2372.33 2415.34 2519.41 2807.08 2017.6 1733 2412.88 2330.09 TRUE FALSE FALSE 2920.610556 2339.606351 2460.250637 2405.345963 2489.367681 2224.859966 2074.208426 2261.383722 2148.193101 2411.060454 1.211338584 0.970364035 1.020401887 0.997629885 1.032478334 0.922772368 0.86028885 0.937920789 0.890974383 1 11.23545211 -5.74716326 0.787805075 1.091691515 0.890539753 0.014349384 0.091969017 0.559558379 0.625122104 0.016729062 0.063605935 1.79E-06 5.74716326 -0.201151762 DEEVHAGLGELLR ddPTM_HeLa_Curcumin_4h_R1 2 DEEVHAGLGELLR 13 0 P50454;E9PR70;E9PPV6;E9PK86;E9PMI5;E9PQ34;E9PJH8;E9PIG2;E9PRS3;E9PNX1 P50454 SERPINH1 Serpin H1 0 0 ; ; 92.295 0.0087753 16792800 14126.2 11635.2 15068.1 13595.7 16059.2 13266.3 9345 7505.6 11163.6 10677.1 FALSE FALSE TRUE 13008.09636 12640.89484 15626.53704 13539.4446 15867.70453 10514.71984 9607.195549 9794.022888 9938.98101 11048.12843 1.177402711 1.144166175 1.41440581 1.22549667 1.436234619 0.951719552 0.869576744 0.88648706 0.899607664 1 13.43151438 -5.019574257 24.40993797 1.148632997 0.886185871 0.398438154 0.156360766 456.3612532 569104.4781 0.022667199 0.058796608 9.56E-06 5.019574257 -0.262447125 DEFEGLFK ddPTM_HeLa_Curcumin_4h_R1 1 DEFEGLFK 8 0 P22314;P22314-2;Q5JRR6 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 0 119.17 0.0028152 1397300 1280.8 1450.4 1256 1248.4 1140.2 1024 963.77 1134.6 1241.2 1135.7 FALSE FALSE TRUE 1179.423329 1575.766113 1302.548465 1243.234452 1126.60386 811.6108571 990.8107923 1480.534317 1105.043465 1175.16549 1.003623182 1.340888688 1.108395775 1.057922873 0.958676773 0.690635373 0.843124479 1.259851765 0.940330085 1 10.19864822 -5.604675177 5.387324657 1.041958506 0.907549378 0.115783418 0.168287497 0.344443764 16.94734987 0.024483271 0.049762371 2.48E-06 5.604675177 -0.134409128 DEILEWESR ddPTM_HeLa_Curcumin_4h_R1 3 DEILEWESR 9 0 Q13596-2;Q13596;Q13596-3;H0YK42 Q13596-2 SNX1 Sorting nexin-1 0 0 ;; ;; 209.58 3.44E-05 29845000 4565.2 4094.4 4387.8 4474.8 4697.8 5154.1 4373.5 4214.5 4485.7 3551.2 FALSE FALSE TRUE 4203.859603 4448.301692 4550.415728 4456.284463 4641.781803 4085.081561 4496.208639 5499.481649 3993.629933 3674.603936 1.14403067 1.210552693 1.238341821 1.21272511 1.263206017 1.111706631 1.223590003 1.496618886 1.086819152 1 11.84337304 -1 0.029880268 5.68E-09 2.936626264 0.543150163 0.084960267 569.8931479 1.319323014 41.70684369 99.81952757 0.1 1 2.936626258 DEILPT(ph)TPISEQK ddPTM_HeLa_Curcumin_4h_R1 1 DEILPTTPISEQK 13 0 E9PL09;P23396;P23396-2;E9PPU1;H0YEU2;E9PSF4 E9PL09 RPS3 40S ribosomal protein S3 1 0 DEILPT(0.708)T(0.287)PIS(0.004)EQK 166.86 0.00053199 15253000 3122.7 3399.3 3379.6 3389.8 3308.5 3859.9 2910.2 4049 3547.3 3571.9 TRUE FALSE FALSE 2875.535 3693.120345 3504.850949 3375.773906 3269.048298 3059.31323 2991.85238 5283.521461 3158.170065 3696.023259 0.77800782 0.999214584 0.948276216 0.913352993 0.884477199 0.827731055 0.809478775 1.429515209 0.854477865 1 11.85175812 -4.255797394 24.9870599 0.895413086 1.429515439 0.832984582 0.072370152 230.0328697 1018732.373 0.012703821 0.149456459 5.55E-05 4.255797394 0.534102353 DEILPTT(ph)PISEQK ddPTM_HeLa_Curcumin_4h_R1 3 DEILPTTPISEQK 13 0 E9PL09;P23396;P23396-2;E9PPU1;H0YEU2;E9PSF4 E9PL09 RPS3 40S ribosomal protein S3 1 0 DEILPT(0.02)T(0.98)PISEQK;DEILPT(0.42)T(0.556)PIS(0.024)EQK;DEILPT(0.234)T(0.765)PISEQK ;; 278.36 9.87E-59 3247377000 38636.4 31250.7 36530.9 34826.2 38499 40953 36379.3 41342 31882.3 29227 TRUE FALSE FALSE 35578.28817 33951.87126 37884.76729 34682.09841 38039.92457 32458.88616 37400.00525 53946.98548 28384.89146 30242.63607 1.176428142 1.122649202 1.252693952 1.146794821 1.257824367 1.073282305 1.236664858 1.783805663 0.938572001 1 14.88429628 -4.261560626 2.844124648 1.116412719 1.904096846 0.811869642 0.095230618 0.131044415 1.461883824 0.013495005 0.237763363 5.48E-05 4.261560626 0.787684127 DEILPTTPISEQK ddPTM_HeLa_Curcumin_4h_R1 2 DEILPTTPISEQK 13 0 E9PL09;P23396;P23396-2;E9PPU1;H0YEU2;E9PSF4 E9PL09 RPS3 40S ribosomal protein S3 0 0 ; ; 251.81 2.87E-62 10120600 8019.3 6964.7 7400.8 7892.2 8558.8 8534.3 7902.6 6903.7 7200.6 6613.9 FALSE FALSE TRUE 7384.563943 7566.697634 7675.080158 7859.544168 8456.7419 6764.189979 8124.325687 9008.606349 6410.712195 6843.732533 1.079025796 1.105639006 1.121475762 1.148429476 1.235691468 0.988377314 1.187119112 1.316329402 0.93672746 1 12.74056766 -1.000000002 0.102593357 0.919680837 1.823588039 0.546164565 0.07495185 73.76695394 0.53728139 0.532936916 9.439344456 0.1 1.000000002 0.903907202 DELADEIANS(ph)SGKGALALEEK ddPTM_HeLa_Curcumin_4h_R1 1 DELADEIANSSGKGALALEEK 21 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 0 DELADEIANS(0.5)S(0.5)GKGALALEEK 68.49 0.0015556 9078500 1670.7 1736.9 1624.1 1634.3 1930.2 1876.3 1456.4 1707.4 1618 1363.5 TRUE FALSE FALSE 1538.462332 1887.029897 1684.290575 1627.5377 1907.183626 1487.13423 1497.262664 2227.9784 1440.509448 1410.881524 1.090426309 1.337482889 1.193785975 1.153560857 1.351767384 1.054046144 1.061224943 1.579139257 1.020999584 1 10.46238113 -1.000002549 0.0292484 9.09E-07 2.873794164 0.296667021 0.147660084 1108.24197 2.512370494 80.1480789 188.3413924 0.099999413 1.000002549 2.873793254 DELADEIANSS(ph)GK ddPTM_HeLa_Curcumin_4h_R1 2 DELADEIANSSGK 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 0 DELADEIANS(0.136)S(0.864)GK;DELADEIANS(0.225)S(0.775)GK ; 234.22 7.51E-20 20731400 6573.1 5463.6 7444.2 5906 9552.2 6645.7 6543.8 6392.3 4641.2 5002.6 TRUE FALSE FALSE 6052.832199 5935.849239 7720.088601 5881.562537 9438.296254 5267.306908 6727.401416 8341.282843 4132.071972 5176.439978 1.169304044 1.146704929 1.491389572 1.136217664 1.823318013 1.017553943 1.299619322 1.611393715 0.798245897 1 12.33774453 -7.37231935 0.578003579 1.023745006 1.403498483 0.37993538 0.232364344 0.616013304 0.469003272 0.071400454 0.077588318 4.24E-08 7.37231935 0.379753477 DELHIVEAEAMNY(ph)EGSPIK ddPTM_HeLa_Curcumin_4h_R1 2 DELHIVEAEAMNYEGSPIK 19 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 0 DELHIVEAEAMNY(0.562)EGS(0.438)PIK;DELHIVEAEAMNY(0.569)EGS(0.431)PIK ; 123.02 5.83E-05 140663000 16205.2 14541.4 17401.4 14031.6 21762.4 19486.5 17718.4 14536 12804 12458.7 TRUE FALSE FALSE 14922.54132 15798.29382 18046.31119 13973.54096 21502.89759 15444.78024 18215.53062 18967.95948 11399.43323 12891.6389 1.157536403 1.225468224 1.399846159 1.083922771 1.667972378 1.198046297 1.412972452 1.4713381 0.884250119 1 13.65414806 -7.138451598 0.346012836 0.980739266 1.462962107 0.560695254 0.149448004 0.69021857 0.238367376 0.095456696 0.123378835 7.27E-08 7.138451598 0.482222842 DELHIVEAEAMNY(ph)EGSPIKVTLATLK ddPTM_HeLa_Curcumin_4h_R1 1 DELHIVEAEAMNYEGSPIKVTLATLK 26 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 0 DELHIVEAEAMNY(0.54)EGS(0.459)PIKVT(0.001)LATLK 64.962 0.00048333 177370000 2441.5 1991.1 2442.4 1919.2 2635.2 3751.7 2732.1 2596.3 2324 2137.7 TRUE FALSE FALSE 2248.252699 2163.201812 2532.917493 1911.258859 2603.776961 2973.55513 2808.755373 3387.899918 2069.063014 2211.984916 1.016396035 0.977946005 1.145088049 0.864046968 1.177122386 1.34429268 1.269789569 1.531610769 0.935387488 1 11.11112583 -5.412127277 2.733406891 1.007735782 1.377685445 0.780870186 0.092514383 0.085896093 1.236570887 0.011641927 0.029018647 3.87E-06 5.412127277 0.369949663 DELHIVEAEAMNYEGS(ph)PIK ddPTM_HeLa_Curcumin_4h_R1 3 DELHIVEAEAMNYEGSPIK 19 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 0 DELHIVEAEAMNYEGS(1)PIK;DELHIVEAEAMNY(0.001)EGS(0.999)PIK;DELHIVEAEAMNYEGS(1)PIK ;; 211.98 1.09E-14 316990000 17710.1 17389.6 18456.7 15419.1 22741.3 21567 19361.9 18758.1 13608.5 13124.1 TRUE FALSE FALSE 16308.3269 18892.67954 19140.72154 15355.29985 22470.12485 17093.76109 19905.1428 24477.35834 12115.6816 13580.1615 1.200893443 1.391196971 1.409461997 1.130715555 1.654628692 1.258730325 1.465751553 1.802434996 0.892160347 1 13.72921302 -1 0.100882575 0.753945622 3.335263573 0.662365855 0.155725737 53.61684922 0.385130312 1.136137528 19.25347909 0.1 1 2.581317952 DELHIVEAEAMNYEGS(ph)PIKVTLATLK ddPTM_HeLa_Curcumin_4h_R1 4 DELHIVEAEAMNYEGSPIKVTLATLK 26 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 0 DELHIVEAEAMNY(0.451)EGS(0.501)PIKVT(0.038)LAT(0.01)LK;DELHIVEAEAMNY(0.438)EGS(0.558)PIKVT(0.003)LATLK;DELHIVEAEAMNY(0.21)EGS(0.789)PIKVT(0.001)LATLK;DELHIVEAEAMNY(0.038)EGS(0.961)PIKVT(0.001)LATLK ;;; 129.43 3.85E-09 316793600 9077.81 8133.51 9098.37 7627.77 8993.49 14551.9 10504.17 9720.67 8310.25 7820.34 TRUE FALSE FALSE 8359.29176 8836.534362 9435.563596 7596.208309 8886.248506 11533.67191 10798.88874 12684.45753 7398.636366 8092.096233 1.033019321 1.091995709 1.166022168 0.938719473 1.098139252 1.425300883 1.334498309 1.567511949 0.914304051 1 12.98229776 -5.300550263 3.535241954 1.029508785 1.438808606 0.828853569 0.085421525 0.06177104 1.605603297 0.010766362 0.026953414 5.01E-06 5.300550263 0.409299821 DELHIVEAEAMNYEGSPIK ddPTM_HeLa_Curcumin_4h_R1 2 DELHIVEAEAMNYEGSPIK 19 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 0 0 ; ; 118.48 0.00098685 15857300 6398.1 6204.8 6572.2 6143.1 7838.4 8316.7 7125.9 6897 5408.6 5758.6 FALSE FALSE TRUE 5891.683634 6741.115264 6815.771513 6117.68148 7744.932199 6591.722671 7325.833576 8999.86355 4815.290112 5958.710921 0.988751378 1.131304296 1.143833222 1.026678683 1.299766393 1.106233002 1.229432619 1.510370895 0.808109367 1 12.54078454 -1 0.30456747 0.988418744 5.036734599 0.696028358 0.10090797 17.24249009 0.220543073 0.029081476 38.76166646 0.1 1 4.048315855 DELT(ph)ESPKYIQK ddPTM_HeLa_Curcumin_4h_R1 1 DELTESPKYIQK 12 1 Q8NC51-2;Q8NC51 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 0 DELT(0.675)ES(0.325)PKYIQK 102.33 0.0065464 64219000 9032 7453.6 8926.4 8971.6 9817.2 14534 14887 8531.7 8698.3 7675.7 TRUE FALSE FALSE 8317.107669 8097.855971 9257.220236 8934.477896 9700.136302 11519.48457 15304.68915 11132.97605 7744.118252 7942.430004 1.047174185 1.01956907 1.165540047 1.124904833 1.221305859 1.450372816 1.926952979 1.401709055 0.97503135 1 12.95536476 -5.31805674 1.639220056 1.037433478 1.673798537 0.767203341 0.134282865 0.115452306 0.587337167 0.018177891 0.060821028 4.81E-06 5.31805674 0.636365059 DELTES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 DELTESPK 8 0 Q8NC51-2;Q8NC51 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 0 DELT(0.331)ES(0.669)PK;DELT(0.224)ES(0.776)PK ; 107.45 0.012039 124291000 10425.8 11177 13117.6 11454 15696.7 14665.7 17871.4 10076.4 8793 8108.1 TRUE FALSE FALSE 9600.586929 12143.09008 13603.7498 11406.60638 15509.5271 11623.8685 18372.82339 13148.64797 7828.429899 8389.855871 1.144308922 1.447353836 1.621452145 1.359571196 1.848604713 1.385467007 2.18988546 1.567207849 0.933082763 1 13.03443031 -6.769736845 0.520120434 1.002969819 1.818364737 0.638921776 0.218725837 0.352631312 0.206341093 0.062100498 0.111845176 1.70E-07 6.769736845 0.815394918 DELTES(ph)PKYIQK ddPTM_HeLa_Curcumin_4h_R1 1 DELTESPKYIQK 12 1 Q8NC51-2;Q8NC51 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 0 DELT(0.013)ES(0.986)PKY(0.001)IQK 86.738 0.0079769 67707000 4841.7 4126.1 4462.3 5145.3 5417.4 7503.1 7798.8 4394 4990.5 3717.4 TRUE FALSE FALSE 4458.474336 4482.741698 4627.676763 5124.010112 5352.801043 5946.872483 8017.613339 5733.710373 4443.054636 3846.579373 1.159075091 1.165383907 1.203062855 1.33209525 1.391574312 1.546015799 2.084348862 1.490599781 1.155066412 1 11.90936036 -5.569196394 0.692289786 1.068877599 1.84932458 0.709494891 0.157330036 0.323600871 0.250406372 0.027869742 0.142350426 2.70E-06 5.569196394 0.780446981 DEQLS(ph)PEEEEK ddPTM_HeLa_Curcumin_4h_R1 1 DEQLSPEEEEK 11 0 P15408;P15408-3;P15408-2;C9JCN8 P15408 FOSL2 Fos-related antigen 2 1 0 DEQLS(1)PEEEEK 142.1 0.0012244 26433000 2123.3 1345.7 1934.2 1732.3 1919.1 1733.5 1699.1 1444.6 1655.1 1332.2 TRUE FALSE FALSE 1955.238565 1462.016312 2005.883153 1725.132202 1896.215986 1373.952559 1746.772173 1885.05189 1473.539671 1378.493851 1.418387585 1.060589651 1.45512666 1.251461659 1.37557087 0.996705614 1.267159931 1.367472106 1.068949034 1 10.42887712 -9.522770823 1.252972981 0.998618157 1.283937733 0.310536574 0.141381593 0.40064544 1.117280666 0.098410447 0.023127814 3.00E-10 9.522770823 0.285319576 DESANQEEPEAR ddPTM_HeLa_Curcumin_4h_R1 2 DESANQEEPEAR 12 0 P50552;K7EM16 P50552 VASP Vasodilator-stimulated phosphoprotein 0 0 ; ; 189.57 6.62E-14 1567090 658.04 443.89 317.15 698.54 849.86 699.13 404.13 639.74 592.03 648.84 FALSE FALSE TRUE 605.9554396 482.2578737 328.903858 695.6496266 839.7259746 554.1225572 415.4688001 834.793781 527.0857902 671.3871417 0.902542515 0.71830073 0.489887038 1.036137846 1.250732882 0.825339842 0.618821503 1.243386608 0.785069831 1 9.391001097 -4.211621247 22.11482962 0.906397071 1.243393634 0.193721082 0.213781976 13808.82789 6129179.671 0.02978388 25.98143914 6.14E-05 4.211621247 0.336996563 DESLKVDEHLAK ddPTM_HeLa_Curcumin_4h_R1 1 DESLKVDEHLAK 12 1 P12429;D6RA82;D6RFJ9 P12429 ANXA3 Annexin A3;Annexin 0 0 83.617 0.0098012 6508200 9740.6 8065.1 8173.6 9106.7 9036.9 11430 8692.1 8254.1 11208 9522.3 FALSE FALSE TRUE 8969.621232 8762.211307 8476.520806 9069.018888 8929.14087 9059.289157 8935.976932 10770.73709 9978.510441 9853.199216 0.910325777 0.889275769 0.860281074 0.920413633 0.90621743 0.919426164 0.906911221 1.093120808 1.012717821 1 13.26637651 -3.169803257 19.45531717 0.941801994 0.93222611 0 0.067194218 0 0 0.008822756 0 0.000676389 3.169803257 -0.009575884 ERVDDSTGTVIS(ph)DVEEDAGELSR ddPTM_HeLa_Curcumin_4h_R1 2 ERVDDSTGTVISDVEEDAGELSR 23 1 Q9Y2D8-2;Q9Y2D8-3;Q9Y2D8;S4R403 Q9Y2D8-2 SSX2IP Afadin- and alpha-actinin-binding protein 1 0 ERVDDSTGTVIS(0.999)DVEEDAGELSR;ERVDDSTGTVIS(1)DVEEDAGELSR ; 206.67 2.63E-18 17610400 2772.89 1753.54 2138.93 2158.59 2462.14 2221.87 984.14 521.79 3015.72 2328.43 TRUE FALSE FALSE 2553.412831 1905.108184 2218.200627 2149.658327 2432.780589 1761.029116 1011.75232 680.881369 2684.903061 2409.342769 1.059796416 0.790716957 0.920666273 0.892217726 1.009727889 0.730916804 0.419928759 0.282600458 1.11437156 1 11.23442394 -4.833672859 1.612954235 0.994045141 0.256213139 0.885167483 0.088723471 0.102429116 0.462456268 0.013347026 0.084135676 1.47E-05 4.833672859 -0.737832002 down DETDSKTAS(ph)PWK ddPTM_HeLa_Curcumin_4h_R1 1 DETDSKTASPWK 12 1 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2;A0A1B0GTD1 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 1 0 DETDSKTAS(1)PWK 136.6 0.015483 25914000 2413.6 1281.8 1258.6 1611.6 779.35 2216.4 1276.1 810.99 3398.5 2108.3 TRUE FALSE FALSE 2222.561013 1392.59308 1305.244823 1604.931626 770.0567603 1756.693656 1311.903932 1058.257118 3025.693053 2181.563268 1.018792829 0.63834641 0.598307114 0.735679615 0.352983923 0.80524534 0.601359562 0.485091188 1.386938026 1 11.0911466 -7.238528042 5.225831354 1.009491464 0.603589342 0.663823507 0.166795132 0.065170923 5.378231551 0.018047541 0.021716934 5.77E-08 7.238528042 -0.405902122 DETEFYLGK ddPTM_HeLa_Curcumin_4h_R1 2 DETEFYLGK 9 0 C9K025;P18077;F8WBS5;F8WB72 C9K025 RPL35A 60S ribosomal protein L35a 0 0 ; ; 152.47 3.46E-09 2578700 4084.4 4248 3668.4 3577.8 4266.8 5201.4 3826.8 3435.3 3460.8 3662.9 FALSE FALSE TRUE 3761.11543 4615.178191 3804.354131 3562.996012 4215.921197 4122.571008 3934.169709 4482.707156 3081.158898 3790.185502 0.992330172 1.217665518 1.003738241 0.940058477 1.11232582 1.087696369 1.037988696 1.182714448 0.812930897 1 11.88805274 -1 0.211182843 0.989766194 1.719069069 0.260709875 0.096576837 56.24320363 0.66146905 0.063662343 13.92218281 0.1 1 0.729302875 DEVVS(ph)PLPSALQGPSGSLSAPPAASVISAPPSSSSR ddPTM_HeLa_Curcumin_4h_R1 2 DEVVSPLPSALQGPSGSLSAPPAASVISAPPSSSSR 36 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 0 DEVVS(0.509)PLPS(0.013)ALQGPS(0.107)GS(0.256)LS(0.107)APPAAS(0.007)VIS(0.002)APPSSSSR;DEVVS(0.938)PLPS(0.007)ALQGPS(0.026)GS(0.026)LS(0.003)APPAASVISAPPSSSSR ; 64.968 4.35E-05 15105500 3114.1 2592.82 3221.5 2733.8 3150.4 2453.19 1761.56 1241.44 3023.5 2747.3 TRUE FALSE FALSE 2867.615699 2816.931807 3340.891624 2722.48826 3112.833538 1944.370741 1810.984633 1619.949341 2691.829614 2842.768471 1.008740504 0.990911443 1.175224665 0.957689058 1.095000725 0.683970841 0.637049641 0.569849201 0.946904274 1 11.47308089 -5.168502673 4.52654646 1.017920185 0.617000845 0.88027974 0.066894313 0.048643453 1.713108488 0.008508875 0.022633351 6.78E-06 5.168502673 -0.40091934 DEYRQDYDAGR ddPTM_HeLa_Curcumin_4h_R1 1 DEYRQDYDAGR 11 1 P52298-3;P52298;C9JQX9;B3KSB0;P52298-2 P52298-3 NCBP2 Nuclear cap-binding protein subunit 2 0 0 102.95 0.0080301 30429000 2505.1 2115.6 1985.3 2229.5 2420.8 2794.6 2044.2 2211.5 2459.7 2520.2 FALSE FALSE TRUE 2306.818692 2298.463037 2058.876964 2220.27492 2391.933541 2214.968458 2101.55475 2885.77617 2189.877064 2607.776762 0.884592088 0.881387959 0.789514269 0.851405286 0.917230944 0.849370426 0.805879852 1.10660399 0.839748668 1 11.34860466 -8.950859415 0.802952386 0.999117554 0.878662325 0 0.095942275 0.699216893 0.837715291 0.049004013 0.015992612 1.12E-09 8.950859415 -0.120455229 DFEEYPEHR ddPTM_HeLa_Curcumin_4h_R1 2 DFEEYPEHR 9 0 O14980 O14980 XPO1 Exportin-1 0 0 ; ; 114.86 0.0060515 9705700 10858 11717.3 12896.7 10950.3 14540.8 10331.2 11238.7 9969.1 7813.5 9826.7 FALSE FALSE TRUE 9998.577843 12730.0912 13374.66305 10904.99056 14367.41046 8188.392663 11554.02767 13008.6327 6956.378598 10168.17709 0.983320584 1.25195412 1.315345211 1.07246269 1.412977992 0.805296032 1.136292923 1.279347574 0.684132321 1 13.31177344 -7.275510657 23.89061888 0.992123598 1.175515556 0.305204944 0.183516663 456.0435286 774282.2042 0.025334287 0.029052953 5.30E-08 7.275510657 0.183391958 DFFHGLR ddPTM_HeLa_Curcumin_4h_R1 2 DFFHGLR 7 0 Q9NTZ6 Q9NTZ6 RBM12 RNA-binding protein 12 0 0 ; ; 119.56 0.0097956 16697700 15028.5 13237.1 15322.4 12269.7 14488.3 32940 22654 19367.6 14218.2 13506.6 FALSE FALSE TRUE 13838.97837 14381.25594 15890.26162 12218.93123 14315.53649 26107.87269 23289.61027 25272.69208 12658.49903 13975.95334 0.990199239 1.028999996 1.13697157 0.874282486 1.024297673 1.868056657 1.66640584 1.808298258 0.905734208 1 13.77065908 -5.266993463 24.99699376 1.00110567 1.769468826 0.950987024 0.081807577 54.55455121 245531.5196 0.009891934 0.022715866 5.41E-06 5.266993463 0.768363156 DFGEEHPFYDR ddPTM_HeLa_Curcumin_4h_R1 3 DFGEEHPFYDR 11 0 Q68CQ4 Q68CQ4 DIEXF Digestive organ expansion factor homolog 0 0 ;; ;; 142.89 0.00093026 25508600 17278.5 14126.6 14797.7 16592.1 16314.6 17308.7 13734.9 10607.8 17673.2 16538.2 FALSE FALSE TRUE 15910.88849 15347.64036 15346.11578 16523.44629 16120.05905 13718.68051 14120.26433 13842.06939 15734.49418 17112.90122 0.929759851 0.896846196 0.896757106 0.965554939 0.941982826 0.801657202 0.825123931 0.808867486 0.919452171 1 14.06279675 -1 0.159312345 1.010530014 0.190146916 0.56408418 0.042228364 26.31506055 0.26551361 0.072208773 5.08461179 0.1 1 -0.820383098 DFK(ac)PGDLIFAK ddPTM_HeLa_Curcumin_4h_R1 1 DFKPGDLIFAK 11 1 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 0 1 DFK(1)PGDLIFAK 103.08 0.00026862 0 166.05 79.564 0 68.665 197.99 346.13 128.8 179.94 245.63 153.88 FALSE TRUE FALSE 152.9069673 86.44115763 0 68.38088242 195.6290986 274.3387363 132.4137814 234.8028777 218.6850035 159.2273185 0.960306113 0.542878938 0 0.429454462 1.228615167 1.722937614 0.831602156 1.474639401 1.373413843 1 7.314944069 -5.552569858 21.20783762 0.828068445 1.322557602 0.317975313 0.411684668 42.45693179 30325.86429 0.061258451 0.122521985 2.80E-06 5.552569858 0.494489156 DFKPGDLIFAK ddPTM_HeLa_Curcumin_4h_R1 1 DFKPGDLIFAK 11 1 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 0 0 93.442 0.0082193 1109300 1753.9 920.66 1524.7 1403 1169.2 1860.9 1208.3 1078.4 928.77 945.26 FALSE FALSE TRUE 1615.076964 1000.237748 1581.206723 1397.194758 1155.258054 1474.928363 1242.201646 1407.199196 826.8862547 978.1077146 1.651226077 1.022625354 1.616597742 1.428467169 1.181115368 1.50794063 1.270004957 1.438695529 0.845393858 1 9.933849541 -9.579214702 1.356510255 0.999528922 1.415497649 0.469037083 0.191554315 0.342461516 1.127838781 0.129964838 0.030195214 2.64E-10 9.579214702 0.415968727 SPGS(ph)TPT(ph)TPTSSQAPQK ddPTM_HeLa_Curcumin_4h_R1 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 0 S(0.003)PGS(0.828)T(0.185)PT(0.732)T(0.244)PT(0.007)S(0.001)SQAPQK 166.04 0.00046689 79779000 4502.6 3894.6 4637.6 3828.6 5053.2 6102.5 7775.1 9162.7 4755.9 4411.2 TRUE FALSE FALSE 4146.214459 4231.23187 4809.473536 3812.758268 4992.94389 4836.772711 7993.24838 11956.36505 4234.189669 4564.488872 0.908363362 0.926989196 1.053671872 0.83530892 1.093867031 1.059652646 1.751181481 2.619431307 0.927637198 1 12.1562376 -4.372337669 1.549275818 0.956331645 3.050634477 0.981134738 0.072349191 0.072345056 0.188479978 0.009881825 0.214474397 4.24E-05 4.372337669 2.094302831 up DFLIPIGK ddPTM_HeLa_Curcumin_4h_R1 1 DFLIPIGK 8 0 P11177-3;P11177-2;P11177;F8WF02;C9J634 P11177-3 PDHB "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial" 0 0 112.17 0.005296 1271500 1531.9 1107.2 1279.1 1368.6 1311.1 2329.7 1444.8 1421.7 1570.1 967.57 FALSE FALSE TRUE 1410.648499 1202.901434 1326.504571 1362.937096 1295.465989 1846.493959 1485.3372 1855.169785 1397.863958 1001.192985 1.408967621 1.2014681 1.324923956 1.361313069 1.293922358 1.844293743 1.483567325 1.852959232 1.396198314 1 9.967504373 -1 0.101994363 0.804791725 3.538857028 0.486021079 0.179178953 53.4008127 0.387071105 1.177894092 20.54292027 0.1 1 2.734065303 DFLLKPELLR ddPTM_HeLa_Curcumin_4h_R1 1 DFLLKPELLR 10 1 Q13838-2;Q13838;Q5STU3;F6U6E2;F6WLT2;F6TRA5;A0A0A0MT12;F6S4E6;A0A0G2JHN7;F6S2B7;F6R6M7;K7EPJ3;A0A0G2JJL7;F6QYI9;F6SXL5;K7ENP6;K7EL56;K7EIL8;K7EN69;K7EQN7;O00148-3;O00148-2;O00148 Q13838-2;K7ENP6 DDX39B;DDX39A Spliceosome RNA helicase DDX39B;ATP-dependent RNA helicase DDX39A 0 0 92.239 0.015287 26618000 3059.1 2564.8 2669.1 2088.2 2688.8 4713.2 3271.6 2935.7 2579.9 2446.7 FALSE FALSE TRUE 2816.969007 2786.489883 2768.019194 2079.559582 2656.737816 3735.629191 3363.392291 3830.781416 2296.891425 2531.722643 1.112668884 1.100629996 1.093334296 0.821401028 1.04937949 1.47552861 1.32849951 1.513112594 0.907244493 1 11.30590365 -5.266363717 24.85273212 1.043031525 1.427992175 0.790546351 0.099775505 122.9744248 620643.9714 0.013367116 0.030805497 5.42E-06 5.266363717 0.38496065 DFLSGPDYDHVTGS(ph)DS(ph)EDEDEEVGEPR ddPTM_HeLa_Curcumin_4h_R1 1 DFLSGPDYDHVTGSDSEDEDEEVGEPR 27 0 Q6ZW31;Q6ZW31-2;M0QXZ8 Q6ZW31 SYDE1 Rho GTPase-activating protein SYDE1 2 0 DFLSGPDY(0.001)DHVT(0.136)GS(0.932)DS(0.932)EDEDEEVGEPR 66.019 0.0014173 5223600 1891.5 1768.5 1732.9 1432.4 1829 2336.4 1566 869.04 1920.6 1709.4 TRUE FALSE FALSE 1741.785779 1921.36126 1797.122798 1426.473108 1807.19037 1851.804303 1609.937745 1134.006295 1709.914985 1768.801523 0.984726526 1.086250342 1.016011562 0.806463071 1.021703309 1.046926 0.91018564 0.641115626 0.966708228 1 10.78855646 -4.299529729 2.986985785 0.992528208 0.598444704 0.691397428 0.070048582 0.138724956 1.869749697 0.009381689 0.123753909 5.02E-05 4.299529729 -0.394083503 DFQDY(ph)MEPEEGCQGSPQR ddPTM_HeLa_Curcumin_4h_R1 1 DFQDYMEPEEGCQGSPQR 18 0 O43237;O43237-2;H3BUM4;B4E2E0 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 0 DFQDY(0.944)MEPEEGCQGS(0.056)PQR 114.71 0.0092112 59758000 3504.3 3023.5 2558.7 2533 3142.5 3136.8 2313.3 2423.8 2688 2858.8 TRUE FALSE FALSE 3226.930957 3284.837868 2653.527673 2522.519117 3105.02774 2486.192321 2378.204972 3162.805462 2393.133125 2958.143087 1.090863715 1.110439141 0.897024787 0.852737357 1.049654343 0.840457087 0.803951973 1.069186097 0.808998434 1 11.53047612 -6.749423157 24.99621183 1.049171608 0.912992511 0.057685907 0.113887108 178.6468236 371621.1005 0.013322169 0.018756731 1.78E-07 6.749423157 -0.136179097 DFQDYMEPEEGCQGS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 9 DFQDYMEPEEGCQGSPQR 18 0 O43237;O43237-2;H3BUM4;B4E2E0 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 0 DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDY(0.076)MEPEEGCQGS(0.924)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR;DFQDYMEPEEGCQGS(1)PQR ;;;;;;;; 266.99 1.12E-53 267455600 22150.65 19792.56 22028.63 21858.45 21470.4 25539.4 19538.91 17694.18 22615.4 19211.53 TRUE FALSE FALSE 20397.40268 21503.34069 22845.03041 21768.00553 21214.3795 20242.24055 20087.11923 23089.05403 20134.5472 19879.12924 1.026071235 1.081704356 1.149196735 1.09501806 1.067168448 1.018265957 1.010462731 1.161472102 1.012848549 1 14.27896694 -7.374836385 3.267529043 1.010897842 1.080407755 0.337594464 0.045404275 0.226987789 4.417573716 0.008325126 0.009461481 4.22E-08 7.374836385 0.069509914 DFQDYMEPEEGCQGS(ph)PQRR ddPTM_HeLa_Curcumin_4h_R1 8 DFQDYMEPEEGCQGSPQRR 19 1 O43237;O43237-2;H3BUM4;B4E2E0 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 0 DFQDY(0.024)MEPEEGCQGS(0.976)PQRR;DFQDYMEPEEGCQGS(1)PQRR;DFQDY(0.001)MEPEEGCQGS(0.999)PQRR;DFQDY(0.005)MEPEEGCQGS(0.995)PQRR;DFQDYMEPEEGCQGS(1)PQRR;DFQDYMEPEEGCQGS(1)PQRR;DFQDYMEPEEGCQGS(1)PQRR;DFQDYMEPEEGCQGS(1)PQRR ;;;;;;; 119.18 0.00011583 501737400 25242.5 20587.3 22162 23263.3 23196.1 26857.7 19999.08 17949.48 24673.5 21391.73 TRUE FALSE FALSE 23244.52949 22366.77448 22983.34322 23167.04263 22919.50166 21287.11027 20560.20036 23422.19382 21966.87878 22135.09103 1.050121251 1.010466795 1.038321604 1.046620617 1.035437425 0.961690659 0.928850951 1.058147617 0.992400653 1 14.43404769 -5.266580232 24.52153422 1.026733286 0.977491863 0.222953091 0.035258359 310.6626627 1481843.697 0.004838857 0.011140885 5.41E-06 5.266580232 -0.049241424 DFQEYVEPGEDFPAS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 5 DFQEYVEPGEDFPASPQR 18 0 Q9Y6G9;E9PHI6;C9JGM7 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 0 DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR;DFQEYVEPGEDFPAS(1)PQR ;;;; 169.05 5.61E-06 130419300 11190.62 10423.7 11280.45 10852.67 13268.4 12747.52 10538.01 10292.66 10283.68 10006.9 TRUE FALSE FALSE 10304.87062 11324.67818 11698.5134 10807.76453 13110.183 10103.54066 10833.6782 13430.84465 9155.586032 10354.63903 0.995193612 1.0936816 1.129784763 1.043760627 1.266116854 0.975750157 1.046263242 1.297084777 0.884201372 1 13.33798964 -7.186827051 3.613163279 0.997405902 1.118175196 0.343551243 0.098970733 0.229211932 5.80976659 0.014651464 0.017896917 6.50E-08 7.186827051 0.120769295 DFQEYVEPGEDFPAS(ph)PQRR ddPTM_HeLa_Curcumin_4h_R1 4 DFQEYVEPGEDFPASPQRR 19 1 Q9Y6G9;E9PHI6;C9JGM7 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 0 DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR;DFQEYVEPGEDFPAS(1)PQRR ;;; 135.68 6.84E-05 1166814000 13101.9 10690.9 11750.5 12150.3 11254.3 14646.2 10608.8 11013 13297.3 10896.2 TRUE FALSE FALSE 12064.87079 11614.97376 12185.98387 12100.02528 11120.09982 11608.41302 10906.45438 14370.813 11838.61946 11274.84214 1.070070041 1.030167307 1.080811928 1.073187999 0.986275434 1.029585415 0.96732657 1.274591061 1.050003123 1 13.46081961 -1.000000024 0.007937002 4.95E-09 2.21948199 0.083827084 0.077850394 34781.24048 21.5651792 2683.002849 3386.27937 0.099999994 1.000000024 2.219481985 DFS(ph)PLQTQTFNR ddPTM_HeLa_Curcumin_4h_R1 1 DFSPLQTQTFNR 12 0 Q6P4F7-3;Q6P4F7 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 0 DFS(1)PLQTQTFNR 170.26 0.00013082 6799500 1000.7 953.64 1046.9 1001.5 1131.1 1584.9 1366.8 588.26 1200.8 937.45 TRUE FALSE FALSE 921.4935391 1036.068392 1085.699035 997.3560584 1117.612371 1256.173874 1405.148729 767.617766 1069.075244 970.0263177 0.949967565 1.068082766 1.119246989 1.028174226 1.152146443 1.294989478 1.448567636 0.791337051 1.102109525 1 9.921880079 -6.368810256 0.973766202 0.978008911 1.19482422 0.078430211 0.165264775 0.535171981 1.008282714 0.027848442 0.055727394 4.28E-07 6.368810256 0.216815309 DFSASYFSGEQEVT(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 DFSASYFSGEQEVTPSR 17 0 P49454 P49454 CENPF Centromere protein F 1 0 DFSASYFSGEQEVT(1)PSR;DFSASYFSGEQEVT(0.942)PS(0.058)R ; 334.04 4.88E-131 62596000 3750 3081.4 2998 3253.8 3429.4 5716.5 5012.3 1178.54 3265.6 2608.4 TRUE FALSE FALSE 3453.183543 3347.742486 3109.108517 3240.336638 3388.506645 4530.833462 5152.931648 1537.871421 2907.37185 2699.041706 1.279410961 1.240344852 1.151930521 1.200550785 1.255448049 1.678682272 1.909170813 0.569784238 1.077186708 1 11.39823155 -5.492078445 7.2249788 1.152826627 1.443679434 0.079173462 0.330259374 0.322639835 59.4897339 0.044708506 0.09816064 3.22E-06 5.492078445 0.290852807 DFSSMK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 DFSSMKK 7 1 G5E9G0;P39023;B5MCW2;H7C3M2;H7C422 G5E9G0 RPL3 60S ribosomal protein L3 0 1 DFSSMK(1)K 77.923 0.019833 3161800 1607.5 1756 1518.3 1804.8 1766.9 2673 1746.3 1722.9 2190.3 1592.2 FALSE TRUE FALSE 1480.264679 1907.780815 1574.569534 1797.332216 1745.830872 2118.589669 1795.296478 2248.204279 1950.02957 1647.528831 0.898475736 1.157965056 0.95571592 1.090926108 1.059666355 1.285919632 1.089690477 1.364591767 1.183608768 1 10.686088 -5.027898312 0.501193425 0.95601241 1.382394493 0.291199388 0.115258139 1.110412197 0.299075882 0.020172551 0.242217645 9.38E-06 5.027898312 0.426382083 DFT(ph)PVCTTELGR ddPTM_HeLa_Curcumin_4h_R1 3 DFTPVCTTELGR 12 0 P30041 P30041 PRDX6 Peroxiredoxin-6 1 0 DFT(0.995)PVCT(0.001)T(0.004)ELGR;DFT(0.805)PVCT(0.191)T(0.004)ELGR;DFT(0.959)PVCT(0.04)T(0.001)ELGR ;; 155.39 0.00099227 59109000 5534.3 5076.5 5558.4 4986.55 5347.2 8448.1 6308 6363.7 5885.1 5262 TRUE FALSE FALSE 5096.254315 5515.29004 5764.399194 4965.916977 5283.438132 6695.86883 6484.985503 8303.962835 5239.519254 5444.854108 0.935976284 1.012936238 1.058687539 0.912038574 0.970354398 1.229760926 1.191030168 1.525102908 0.962288272 1 12.41067768 -3.814769531 0.753074105 0.971857532 2.247497969 0.877407028 0.062541219 1.083928665 0.275975838 0.010150109 1.363473477 0.00015319 3.814769531 1.275640436 DFTNEAPPAPLPDAS(ph)ASPLSPHR ddPTM_HeLa_Curcumin_4h_R1 1 DFTNEAPPAPLPDASASPLSPHR 23 0 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 DFTNEAPPAPLPDAS(0.452)AS(0.395)PLS(0.153)PHR 67.799 0.00095408 4030400 1494.6 1331.2 1336.5 1340.1 1976.8 1994.1 1251.1 860.36 1708.9 1303.6 TRUE FALSE FALSE 1376.300833 1446.262996 1386.031866 1334.555021 1953.227951 1580.501182 1286.202499 1122.679803 1521.437945 1348.900003 1.020313463 1.072179549 1.027527513 0.989365422 1.448015381 1.171696329 0.953519531 0.832292832 1.127910106 1 10.39756769 -6.907715134 1.259688244 1.008582553 1.089344887 0 0.157107041 1.165963382 3.66315564 0.029952455 0.041794817 1.24E-07 6.907715134 0.080762334 DFTNEAPPAPLPDASAS(ph)PLSPHR ddPTM_HeLa_Curcumin_4h_R1 2 DFTNEAPPAPLPDASASPLSPHR 23 0 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 DFTNEAPPAPLPDAS(0.079)AS(0.563)PLS(0.358)PHR;DFTNEAPPAPLPDAS(0.247)AS(0.469)PLS(0.284)PHR ; 118.98 2.26E-06 61008000 8675.6 8304.1 8462.5 8130.4 10117.5 9792.6 6852.5 4802.5 8737.7 7832.8 TRUE FALSE FALSE 7988.917106 9021.869402 8776.127694 8096.758559 9996.85542 7761.504375 7044.762707 6266.760142 7779.196171 8104.989217 0.985678931 1.113125405 1.082805598 0.998984495 1.233419953 0.957620568 0.869188412 0.773197838 0.959803395 1 12.98459455 -4.709563664 2.754272188 1.025093308 0.793653541 0.559469261 0.080263877 0.16626178 2.436192992 0.011512019 0.056189961 1.95E-05 4.709563664 -0.231439766 DFTNEAPPAPLPDASASPLS(ph)PHRR ddPTM_HeLa_Curcumin_4h_R1 2 DFTNEAPPAPLPDASASPLSPHRR 24 1 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 DFTNEAPPAPLPDAS(0.047)AS(0.148)PLS(0.806)PHRR;DFTNEAPPAPLPDAS(0.116)AS(0.22)PLS(0.665)PHRR ; 126.55 4.28E-07 99183000 5324.7 4853.4 4932.4 4755.4 5582.6 6682.4 4380.7 3149.7 5249.9 4905.2 TRUE FALSE FALSE 4903.244376 5272.90627 5115.199083 4735.723415 5516.031141 5296.394914 4503.610652 4110.029031 4673.999105 5075.655335 0.966031784 1.038862161 1.007790866 0.933026989 1.086762354 1.043489868 0.887296389 0.809753374 0.920866134 1 12.30937839 -4.57195614 4.34418106 0.995965718 0.824051653 0.624273167 0.048426752 0.082478549 3.229813838 0.006064055 0.027063987 2.68E-05 4.57195614 -0.171914066 DFTPVCTTELGR ddPTM_HeLa_Curcumin_4h_R1 2 DFTPVCTTELGR 12 0 P30041 P30041 PRDX6 Peroxiredoxin-6 0 0 ; ; 185.96 7.98E-10 22475000 2676.6 2230.82 2317.4 2254.08 2361.8 3338 2401.5 2210.7 2429.1 2106.41 FALSE FALSE TRUE 2464.744286 2423.64214 2403.284883 2244.753214 2333.637078 2645.661173 2468.879627 2884.732253 2162.633807 2179.607591 1.130820197 1.111962608 1.102622735 1.029888694 1.070668449 1.213824536 1.132717484 1.323509913 0.992212459 1 11.08985271 -1 0.448696099 1.061003159 6.432049022 0.671123638 0.054798097 39.73001715 0.429904062 0.013160576 197.0169666 0.1 1 5.371045863 DFVDDDDDDDLER ddPTM_HeLa_Curcumin_4h_R1 2 DFVDDDDDDDLER 13 0 G3V4K3;Q9H9C1-2;Q9H9C1 G3V4K3 VIPAS39 Spermatogenesis-defective protein 39 homolog 0 0 ; ; 292.33 4.38E-72 77029000 4503.3 3708.7 3734.9 4136.9 4094.7 5248.4 3493 3522.5 3473.8 3753.6 FALSE FALSE TRUE 4146.859053 4029.263502 3873.31868 4119.782604 4045.873377 4159.822678 3591.004179 4596.494034 3092.732831 3884.037321 1.067667149 1.037390522 0.997240335 1.060695937 1.041666967 1.071004817 0.924554499 1.183431995 0.796267537 1 11.92334135 -9.525506068 1.267493256 0.999869318 1.045712772 0.150927452 0.089364368 0.974153793 2.789517134 0.038652833 0.009151197 2.98E-10 9.525506068 0.045843454 DFVTIS(ph)PVQPEER ddPTM_HeLa_Curcumin_4h_R1 1 DFVTISPVQPEER 13 0 Q9H611-2;Q9H611-4;Q9H611;Q9H611-3 Q9H611-2 PIF1 ATP-dependent DNA helicase PIF1 1 0 DFVT(0.005)IS(0.995)PVQPEER 84.753 0.017514 3088600 1229 1180.6 1046.8 1280.7 1070.9 1499.4 1332.4 446.31 980.85 1112.5 TRUE FALSE FALSE 1131.723353 1282.645803 1085.595329 1275.400803 1058.130217 1188.407538 1369.783558 582.3878644 873.253209 1151.159292 0.983116204 1.114220953 0.943045273 1.107927297 0.919186618 1.032357161 1.189916606 0.505914228 0.758585901 1 10.16887177 -4.248703483 24.99996716 1.012213177 0.505913908 0.632306875 0.114154204 672.6247389 1320308.464 0.01027551 0.249844375 5.64E-05 4.248703483 -0.506299269 DFYLAT(ph)SPPDSFLDDHHLTRPHPER ddPTM_HeLa_Curcumin_4h_R1 1 DFYLATSPPDSFLDDHHLTRPHPER 25 1 Q13131;Q13131-2 Q13131 PRKAA1 5-AMP-activated protein kinase catalytic subunit alpha-1 1 0 DFY(0.009)LAT(0.833)S(0.155)PPDS(0.003)FLDDHHLTRPHPER 84.107 2.56E-05 3929700 1449.5 1418.9 1445.9 1561.2 1968.8 2200.8 1280.9 867.87 2127.3 1545.8 TRUE FALSE FALSE 1334.770545 1541.543394 1499.486326 1554.740168 1945.323346 1744.329272 1316.838607 1132.479568 1893.940512 1599.516435 0.834483795 0.963755895 0.937462281 0.972006373 1.216194659 1.090535385 0.823272945 0.708013712 1.18407068 1 10.6434201 -4.161738247 0.002375224 1.86247427 2.43E-06 0 0.154022793 1597316.042 578.54072 222851.8076 230853.019 6.89E-05 4.161738247 -1.862471837 DGADFAK ddPTM_HeLa_Curcumin_4h_R1 1 DGADFAK 7 0 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7;H3BR04;H3BMQ8;H3BU78;P09972;K7EKH5;C9J8F3;J3KSV6;J3QKP5;A8MVZ9 P04075;P09972 ALDOA;ALDOC Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase;Fructose-bisphosphate aldolase C 0 0 111.65 0.012814 25881000 4017.6 3721.9 3884.6 3213.1 3346.8 4711.7 2758.9 2709.3 3687.1 4055.5 FALSE FALSE TRUE 3699.602721 4043.604452 4028.566693 3199.805044 3306.891596 3734.440308 2836.307309 3535.353098 3282.634355 4196.428323 0.881607509 0.963582394 0.959998928 0.762506779 0.788025278 0.889909232 0.675886037 0.842467171 0.782244829 1 12.03494622 -6.264521759 24.77540894 0.945528673 0.790566889 0.369323546 0.077947451 128.138786 1029948.802 0.009786804 0.015352791 5.44E-07 6.264521759 -0.154961785 DGADFAK(ac)WR ddPTM_HeLa_Curcumin_4h_R1 2 DGADFAKWR 9 1 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7;H3BR04;H3BMQ8;H3BU78;P09972;K7EKH5;C9J8F3;J3KSV6;J3QKP5;A8MVZ9 P04075;P09972 ALDOA;ALDOC Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase;Fructose-bisphosphate aldolase C 0 1 ; DGADFAK(1)WR;DGADFAK(1)WR 122.33 0.0011545 65520000 10774.1 15531.6 7963.2 12518.2 9321.2 8640.8 8670.7 7128.5 14586.9 12849.2 FALSE TRUE FALSE 9921.318616 16874.0823 8258.323197 12466.40301 9210.050778 6848.600678 8913.976506 9301.946834 12986.75356 13295.70874 0.746204569 1.269137481 0.621126963 0.93762606 0.692708524 0.515098579 0.670440116 0.699620232 0.97676279 1 13.69867306 -5.653762272 4.673342051 0.891663646 0.62852254 0.398755753 0.166855184 0.184293408 6.784642387 0.024401918 0.049711585 2.22E-06 5.653762272 -0.263141106 LSPS(ph)PTTEDPR ddPTM_HeLa_Curcumin_4h_R1 2 LSPSPTTEDPR 11 0 F6RRE2;E7EV10;Q9BTC8;E7EQY4;Q9BTC8-2 F6RRE2 MTA3 Metastasis-associated protein MTA3 1 0 LS(0.001)PS(0.598)PT(0.387)T(0.014)EDPR;LS(0.007)PS(0.473)PT(0.312)T(0.208)EDPR ; 165.66 0.00026742 48682000 4892.1 3844.6 4049.8 4405 4704.3 5411.8 6697.1 7842.9 3635.4 3732.3 TRUE FALSE FALSE 4504.885123 4176.910093 4199.889151 4386.773277 4648.204295 4289.331676 6885.002602 10234.16411 3236.605715 3861.997147 1.166465161 1.081541475 1.087491521 1.13588206 1.203575279 1.110651177 1.78275704 2.64996677 0.838065279 1 11.91513138 -4.369108716 1.753666186 1.089587813 2.990330935 0.95947061 0.101488228 0.072836886 0.260584539 0.011056635 0.213417413 4.27E-05 4.369108716 1.900743122 up DGAGLGLS(ph)GGSPGASTPVLLTR ddPTM_HeLa_Curcumin_4h_R1 1 DGAGLGLSGGSPGASTPVLLTR 22 0 Q8N612;Q8N612-2 Q8N612 FAM160A2 FTS and Hook-interacting protein 1 0 DGAGLGLS(0.995)GGS(0.005)PGASTPVLLTR 152.64 1.88E-06 9038400 1734.7 1562.2 1538.9 1988.8 1956.4 2847.5 2105.9 482.98 1867.8 1534.1 TRUE FALSE FALSE 1597.396665 1697.229607 1595.932988 1980.570873 1933.071208 2256.896402 2164.985886 630.2383786 1662.907013 1587.409861 1.006291257 1.069181721 1.005369204 1.247674543 1.217751795 1.421747753 1.363848077 0.397023097 1.047559962 1 10.63245896 -6.283819655 22.26749698 1.009228994 1.163749068 0.027174705 0.266383885 409.4086283 407344.7033 0.038506532 0.05886787 5.20E-07 6.283819655 0.154520074 DGAGLGLSGGS(ph)PGASTPVLLTR ddPTM_HeLa_Curcumin_4h_R1 1 DGAGLGLSGGSPGASTPVLLTR 22 0 Q8N612;Q8N612-2 Q8N612 FAM160A2 FTS and Hook-interacting protein 1 0 DGAGLGLS(0.037)GGS(0.535)PGAS(0.217)T(0.208)PVLLT(0.003)R 67.56 0.0028913 13391000 1457.4 1624.3 1530.5 1728.1 1685 2583.3 1724.7 462.93 1568.3 1434.3 TRUE FALSE FALSE 1342.045252 1764.697254 1587.221676 1720.94958 1664.907476 2047.49446 1773.09044 604.0752259 1396.261414 1484.141818 0.904256747 1.189035463 1.069454183 1.159558715 1.121798102 1.379581409 1.194690708 0.407019881 0.940787057 1 10.53541324 -7.272870383 23.82375449 0.954787907 1.095711483 0.049050187 0.241583219 826.3184863 1722155.995 0.039524685 0.04543305 5.33E-08 7.272870383 0.140923576 GTT(ph)PPPPSWEPNSQTK ddPTM_HeLa_Curcumin_4h_R1 1 GTTPPPPSWEPNSQTK 16 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 0 GT(0.028)T(0.972)PPPPSWEPNSQTK 107.74 0.0052154 3596400 1426.1 1263.8 1406.1 1674.6 1484.6 1428.8 593.9 308.09 1242 1589.1 TRUE FALSE FALSE 1313.22268 1373.037241 1458.211303 1667.670949 1466.897115 1132.450774 610.5632356 402.0252227 1105.755707 1644.321107 0.79864126 0.835017707 0.88681663 1.014200293 0.892098939 0.688704152 0.371316304 0.244493135 0.672469448 1 10.68327634 -4.833170151 1.965023514 0.904303178 0.244730013 0.842861134 0.096171676 0.08316016 0.599418461 0.012553589 0.065755986 1.47E-05 4.833170151 -0.659573165 down DGAVNGPSVVGDQT(ph)PIEPQTSIER ddPTM_HeLa_Curcumin_4h_R1 1 DGAVNGPSVVGDQTPIEPQTSIER 24 0 P49321-4;P49321;P49321-3 P49321-4 NASP Nuclear autoantigenic sperm protein 1 0 DGAVNGPSVVGDQT(1)PIEPQTSIER 94.045 3.52E-05 9616300 1192 1196.9 1094.4 1092.6 1133 1386.7 1074.5 1057.1 1539 1410.8 TRUE FALSE FALSE 1097.651942 1300.354703 1134.959427 1088.079111 1119.489715 1099.082789 1104.647578 1379.404924 1370.17555 1459.825195 0.751906424 0.890760556 0.777462556 0.745348905 0.766865594 0.752886573 0.756698529 0.944911027 0.938588781 1 10.51157991 -9.373082337 0.81976223 1.016918294 0.790935188 0.506146259 0.066242416 0.408476469 0.429955104 0.062223551 0.012020855 4.24E-10 9.373082337 -0.225983106 DGDGVPGGGPLS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 1 DGDGVPGGGPLSPAR 15 0 M0QZR4;Q92888-2;Q92888;Q92888-3 M0QZR4 ARHGEF1 Rho guanine nucleotide exchange factor 1 1 0 DGDGVPGGGPLS(1)PAR 196.97 9.75E-07 37715000 2527.6 2180.2 2078.9 2103.9 2510.2 2687.2 2081.1 4582.4 2154.7 1744.8 TRUE FALSE FALSE 2327.537793 2368.646773 2155.945863 2095.194619 2480.267504 2129.844429 2139.490065 5979.552665 1918.334801 1805.43167 1.28918631 1.311955923 1.194144258 1.160495107 1.373780878 1.179687088 1.185029653 3.311979492 1.062535255 1 10.8181281 -4.261436569 9.277132612 1.177076093 3.319996319 0.972370935 0.107005915 0.010849805 21.2055501 0.018548195 0.144597053 5.48E-05 4.261436569 2.142920226 DGDSVMVLPTIPEEEAK ddPTM_HeLa_Curcumin_4h_R1 1 DGDSVMVLPTIPEEEAK 17 0 P30041 P30041 PRDX6 Peroxiredoxin-6 0 0 113.07 0.0051312 4840300 2492.7 1851 2122.7 2071.7 2684.5 2743 1971.8 1776.3 2232.1 2092.9 FALSE FALSE TRUE 2295.400165 2010.992192 2201.369129 2063.127854 2652.489091 2174.07088 2027.123401 2317.885693 1987.244214 2165.628119 1.059923513 0.928595346 1.016503762 0.952669499 1.224812823 1.003898528 0.93604409 1.070306426 0.917629484 1 11.08056981 DGDSYDPYDFS(ph)DT(ph)EEEMPQVHT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 3 0 DGDS(0.051)Y(0.048)DPY(0.333)DFS(0.912)DT(0.922)EEEMPQVHT(0.735)PK;DGDS(0.007)Y(0.012)DPY(0.084)DFS(0.972)DT(0.971)EEEMPQVHT(0.953)PK;DGDSYDPY(0.009)DFS(0.999)DT(1)EEEMPQVHT(0.992)PK;DGDS(0.007)Y(0.012)DPY(0.229)DFS(0.987)DT(0.986)EEEMPQVHT(0.779)PK ;;; 71.299 0.0022463 81483000 8752.27 7291.41 7771.2 7900.19 7846.58 9765.7 8039.2 7029.97 8755.18 8358.24 TRUE FALSE FALSE 8059.518594 7921.646991 8059.207508 7867.501107 7753.014658 7740.183738 8264.758316 9173.375491 7794.758658 8648.688218 0.931877574 0.915936243 0.931841605 0.909675654 0.896438218 0.89495465 0.955608308 1.060666688 0.901264846 1 13.07826561 -9.073089228 0.849877537 1.000038897 0.933404631 0 0.054346458 0.737322434 0.966385946 0.030376782 0.009075643 8.45E-10 9.073089228 -0.066634266 DGDSYDPYDFS(ph)DT(ph)EEEMPQVHTPK ddPTM_HeLa_Curcumin_4h_R1 8 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 2 0 DGDSYDPY(0.026)DFS(0.982)DT(0.963)EEEMPQVHT(0.029)PK;DGDSY(0.001)DPY(0.01)DFS(0.991)DT(0.996)EEEMPQVHT(0.002)PK;DGDS(0.01)Y(0.007)DPY(0.087)DFS(0.971)DT(0.923)EEEMPQVHT(0.002)PK;DGDS(0.02)Y(0.023)DPY(0.158)DFS(0.908)DT(0.869)EEEMPQVHT(0.022)PK;DGDSYDPY(0.001)DFS(0.999)DT(0.997)EEEMPQVHT(0.003)PK;DGDS(0.004)Y(0.009)DPY(0.068)DFS(0.957)DT(0.961)EEEMPQVHTPK;DGDSYDPY(0.091)DFS(0.952)DT(0.946)EEEMPQVHT(0.01)PK;DGDSYDPY(0.004)DFS(0.998)DT(0.998)EEEMPQVHTPK ;;;;;;; 105.95 4.00E-06 1147229900 35662.8 29019.1 31711.3 33205.2 32399 38709.4 29601.8 27366.56 36769.4 32261.1 TRUE FALSE FALSE 32840.05175 31527.3817 32886.54867 33067.80568 32012.66309 30680.6341 30432.34684 35710.49816 32735.88881 33382.17082 0.983760221 0.944437732 0.985153088 0.990582843 0.958974875 0.919072467 0.911634747 1.069747631 0.980639905 1 15.02679015 -7.834322538 0.70708221 0.998165369 0.964126382 0.021961955 0.042406447 1.068043701 1.186400406 0.013838018 0.011000233 1.46E-08 7.834322538 -0.034038987 DGDSYDPYDFS(ph)DTEEEMPQVHT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 2 0 DGDSYDPY(0.001)DFS(0.928)DT(0.352)EEEMPQVHT(0.719)PK;DGDS(0.002)YDPY(0.002)DFS(0.859)DT(0.267)EEEMPQVHT(0.87)PK;DGDSYDPY(0.003)DFS(0.656)DT(0.353)EEEMPQVHT(0.987)PK;DGDSYDPY(0.006)DFS(0.874)DT(0.163)EEEMPQVHT(0.957)PK ;;; 94.016 3.78E-05 395304300 19999.9 16561.1 16660.6 18303.9 17174.1 19614.2 15899.2 13528.4 20220.8 17020.5 TRUE FALSE FALSE 18416.88681 17992.56769 17278.05649 18228.16331 16969.31007 15545.99382 16345.28876 17653.14688 18002.62883 17611.96111 1.045703355 1.021610687 0.981041031 1.034987711 0.963510535 0.882695216 0.928078859 1.002338512 1.022181955 1 14.10426794 -5.609290554 4.745384019 1.019400813 0.934673916 0.566445509 0.031927993 0.111926587 4.466873094 0.004869559 0.009984121 2.46E-06 5.609290554 -0.084726897 DGDSYDPYDFS(ph)DTEEEMPQVHTPK ddPTM_HeLa_Curcumin_4h_R1 4 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 0 DGDSYDPYDFS(0.866)DT(0.133)EEEMPQVHTPK;DGDSYDPY(0.005)DFS(0.773)DT(0.22)EEEMPQVHT(0.001)PK;DGDSYDPY(0.003)DFS(0.674)DT(0.321)EEEMPQVHT(0.002)PK;DGDSYDPYDFS(0.727)DT(0.273)EEEMPQVHTPK ;;; 114.91 3.61E-07 778864000 18158 18805 16539.4 17816.2 17492.1 19508.3 12884 13431.9 19287.3 17959.6 TRUE FALSE FALSE 16720.77514 20430.42041 17152.36471 17742.48129 17283.51813 15462.05868 13245.49036 17527.22448 17171.53144 18583.69476 0.899755154 1.099373438 0.922979253 0.954733787 0.930036699 0.83202285 0.712747951 0.943150687 0.924010627 1 14.18174974 -5.317561341 3.225246992 0.960891283 0.815376291 0.407210532 0.073652309 0.179430471 3.708725136 0.010461883 0.026439437 4.81E-06 5.317561341 -0.145514992 DGDSYDPYDFSDT(ph)EEEMPQVHT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 2 0 DGDSYDPYDFS(0.076)DT(0.924)EEEMPQVHT(1)PK;DGDSYDPY(0.002)DFS(0.425)DT(0.663)EEEMPQVHT(0.91)PK;DGDS(0.002)Y(0.007)DPY(0.086)DFS(0.46)DT(0.537)EEEMPQVHT(0.909)PK;DGDSYDPYDFS(0.402)DT(0.622)EEEMPQVHT(0.976)PK ;;; 86.933 0.0001793 193335100 12418.9 10919.2 10584.3 11611.6 11034 13180.2 11552.6 8632.4 11812.9 10348.2 TRUE FALSE FALSE 11435.93096 11863.00699 10976.56347 11563.55428 10902.42676 10446.47795 11876.73486 11264.37902 10517.05442 10707.79918 1.068000134 1.10788471 1.025099863 1.079918859 1.018176245 0.975595244 1.109166754 1.05197892 0.982186372 1 13.38637437 -9.317618391 1.089852505 1.000588275 1.054771125 0.281900184 0.039447392 0.617352121 1.334260363 0.024812328 0.006878493 4.81E-10 9.317618391 0.05418285 DGDSYDPYDFSDT(ph)EEEMPQVHTPK ddPTM_HeLa_Curcumin_4h_R1 8 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 0 DGDSYDPYDFS(0.309)DT(0.691)EEEMPQVHTPK;DGDSYDPYDFS(0.039)DT(0.961)EEEMPQVHTPK;DGDSYDPYDFS(0.464)DT(0.536)EEEMPQVHTPK;DGDS(0.001)YDPY(0.002)DFS(0.2)DT(0.796)EEEMPQVHTPK;DGDSYDPYDFS(0.001)DT(0.999)EEEMPQVHTPK;DGDSYDPYDFS(0.027)DT(0.914)EEEMPQVHT(0.06)PK;DGDSYDPYDFS(0.453)DT(0.546)EEEMPQVHTPK;DGDSYDPYDFS(0.058)DT(0.942)EEEMPQVHTPK ;;;;;;; 115.39 8.26E-07 1984635000 41826.2 35594.4 35826.5 36738.3 36541.1 43645.3 28150.3 27939.6 41961.2 34707.2 TRUE FALSE FALSE 38515.61214 38671.02133 37154.26161 36586.28665 36105.37125 34592.7728 28940.12166 36458.25542 37358.16134 35913.27262 1.072461776 1.076789123 1.034555163 1.018739981 1.005348959 0.963230869 0.805833597 1.015174969 1.040232722 1 15.1322295 -5.228280056 2.460793175 1.036817143 0.907529136 0.480696099 0.052718162 0.177335434 2.087865444 0.007542487 0.022214006 5.91E-06 5.228280056 -0.129288006 DGDSYDPYDFSDTEEEMPQVHT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 DGDSYDPYDFSDTEEEMPQVHTPK 24 0 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 0 DGDSYDPYDFSDT(0.014)EEEMPQVHT(0.986)PK 115.06 6.76E-07 36577000 7279.4 5477.7 4982.6 5283.2 5132.7 5995.3 3884.3 3191.4 5688.9 4733.2 TRUE FALSE FALSE 6703.227809 5951.16798 5167.259539 5261.339518 5071.495905 4751.807199 3993.283004 4164.443169 5064.841903 4897.678348 1.368654153 1.2150998 1.055042649 1.074251746 1.035489786 0.970216266 0.81534203 0.850289234 1.034131183 1 12.25788231 -5.351833246 0.907946051 1.17499742 0.809609073 0.546094459 0.102845106 0.509797906 0.694823993 0.02398975 0.126562737 4.45E-06 5.351833246 -0.365388347 DGDYRDQDYRTEQGEEEEEEEDEEEEEKASNIVMLR ddPTM_HeLa_Curcumin_4h_R1 1 DGDYRDQDYRTEQGEEEEEEEDEEEEEKASNIVMLR 36 3 P98175-5;P98175-2;P98175 P98175-5 RBM10 RNA-binding protein 10 0 0 39.143 0.0088648 5233300 1036.9 680.17 750.04 885.97 710.38 1060.8 639.97 740.52 1455.4 972.37 FALSE FALSE TRUE 954.8282709 738.960864 777.8371422 882.3040909 701.9091825 840.7781223 657.9258358 966.3011391 1295.746261 1006.159785 0.948982741 0.734436891 0.773075165 0.87690256 0.697612042 0.835630816 0.653897965 0.960385372 1.287813606 1 9.974643718 -7.363383613 4.806487327 0.977819238 0.786137183 0.465392094 0.128906104 0.117165739 4.309839309 0.013072653 0.014880972 4.33E-08 7.363383613 -0.191682055 DGEEAGAYDGPR ddPTM_HeLa_Curcumin_4h_R1 3 DGEEAGAYDGPR 12 0 H7BZJ3;P30101 H7BZJ3;P30101 PDIA3 Protein disulfide-isomerase A3 0 0 ;; ;; 144.77 0.0047398 36708600 7003.6 5708.5 6554.5 6286.1 6950.6 7447.6 5056.2 4175.5 6258.3 5766.3 FALSE FALSE TRUE 6449.25767 6201.917303 6797.415536 6260.089784 6867.718635 5902.883808 5198.063364 5448.590728 5571.780147 5966.678496 1.080879031 1.03942542 1.139229396 1.049174979 1.151012014 0.989308174 0.871182077 0.91316982 0.93381605 1 12.54271233 -4.942740093 4.680575365 1.054819031 0.895251269 0.540217579 0.060091195 0.099529483 4.503172753 0.007360621 0.023099554 1.14E-05 4.942740093 -0.159567762 DGES(ph)DGFADEEES(ph)GEEGEEDQEEGREPGAGR ddPTM_HeLa_Curcumin_4h_R1 1 DGESDGFADEEESGEEGEEDQEEGREPGAGR 31 1 P48681 P48681 NES Nestin 2 0 DGES(1)DGFADEEES(1)GEEGEEDQEEGREPGAGR 125.95 9.02E-13 17767000 1137.7 1090.3 758.49 843.69 1315.2 1165.7 971.98 1003.3 958.39 831.43 TRUE FALSE FALSE 1047.649845 1184.540674 786.6003066 840.1990343 1299.517099 923.9206799 999.2511428 1309.201551 853.2570148 860.3221306 1.217741364 1.376857146 0.914309046 0.976609812 1.510500605 1.073924112 1.161484876 1.52175738 0.991787825 1 9.748733139 -13.52287415 0.039756654 5.19E-21 1.81939973 0.218065617 0.189093574 926.3833162 2.940427239 116.6486975 38.15862023 3.00E-14 13.52287415 1.81939973 DGESDGFADEEES(ph)GEEGEEDQEEGREPGAGR ddPTM_HeLa_Curcumin_4h_R1 2 DGESDGFADEEESGEEGEEDQEEGREPGAGR 31 1 P48681 P48681 NES Nestin 1 0 DGESDGFADEEES(1)GEEGEEDQEEGREPGAGR;DGES(0.071)DGFADEEES(0.929)GEEGEEDQEEGREPGAGR ; 109.42 3.74E-11 41145000 2904.5 1661.21 1900.76 2162.32 2565.75 2187.02 2165.63 3177.3 2134.2 1876.08 TRUE FALSE FALSE 2674.60576 1804.79759 1971.203838 2153.372893 2535.155107 1733.407399 2226.391749 4146.044144 1900.0836 1941.27364 1.377758243 0.929697675 1.015417815 1.109257782 1.305923624 0.892922751 1.146871674 2.135734014 0.97878195 1 10.92278778 -4.261722073 8.246259635 1.13731528 2.142660925 0.79591413 0.157707252 0.034479383 32.39462258 0.024623582 0.193405749 5.47E-05 4.261722073 1.005345644 DGFIDKEDLHDMLASLGK ddPTM_HeLa_Curcumin_4h_R1 1 DGFIDKEDLHDMLASLGK 18 1 J3QRS3;P19105;O14950;J3KTJ1;P24844 J3QRS3;P24844 MYL12A;MYL12B;MYL9 Myosin regulatory light chain 12A;Myosin regulatory light chain 12B;Myosin regulatory light polypeptide 9 0 0 59.252 0.013895 35485000 10922 10098 11596 9318.2 14306 21376 16926 14442 10639 8281.3 FALSE FALSE TRUE 10057.51218 10970.82612 12025.75796 9279.643757 14135.41029 16942.37664 17400.89801 18845.29932 9471.928317 8569.074559 1.173698759 1.280281324 1.403390515 1.082922513 1.649584234 1.977153604 2.030662458 2.199222237 1.105361875 1 13.06492369 -5.069204856 0.53624282 1.066363364 2.549686653 0.903786859 0.130253927 0.408937902 0.131865053 0.028848236 0.323545223 8.53E-06 5.069204856 1.483323289 up TVS(ph)PSTIR ddPTM_HeLa_Curcumin_4h_R1 1 TVSPSTIR 8 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 0 T(0.209)VS(0.754)PS(0.038)TIR 96.665 0.017005 417670000 5890 5059.3 5233.9 5259.8 5465.4 5044.5 3141.3 1736.9 5359.4 5048.1 TRUE FALSE FALSE 5423.800285 5496.603348 5427.872938 5238.036341 5400.228675 3998.213837 3229.436424 2266.472814 4771.487229 5223.521099 1.038341797 1.052279343 1.039121473 1.002778823 1.033829207 0.765425038 0.618248948 0.433897513 0.913461847 1 12.35080692 -4.824433774 1.439432346 1.024944269 0.425904587 0.94661181 0.047015212 0.052891893 0.17890063 0.004669507 0.033687871 1.50E-05 4.824433774 -0.599039682 down DGGEALVS(ph)PDGTVTEAPR ddPTM_HeLa_Curcumin_4h_R1 2 DGGEALVSPDGTVTEAPR 18 0 Q96HN2-2;Q96HN2 Q96HN2-2 AHCYL2 Putative adenosylhomocysteinase 3 1 0 DGGEALVS(0.944)PDGT(0.044)VT(0.012)EAPR;DGGEALVS(0.985)PDGT(0.015)VTEAPR ; 182.09 5.64E-07 14863700 2819.53 2335.46 2536.5 2328.69 3164.9 4176.9 4185 3239.75 2784.15 2362.31 TRUE FALSE FALSE 2596.361225 2537.326756 2630.504921 2319.054498 3127.160635 3310.563857 4302.419837 4227.534861 2478.735711 2444.400097 1.062167044 1.038016141 1.076135173 0.948721325 1.279316197 1.354346149 1.760112775 1.729477456 1.014046642 1 11.25526473 -5.049950116 1.323055473 1.029568866 1.801279945 0.943143995 0.068096943 0.073269649 0.220153319 0.009387551 0.051088309 8.91E-06 5.049950116 0.771711078 DGGFCEVCK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 DGGFCEVCKK 10 1 Q5BJH1;C9JIZ6;P07602;P07602-2;P07602-3 Q5BJH1 PSAP Prosaposin;Saposin-A;Saposin-B-Val;Saposin-B;Saposin-C;Saposin-D 0 1 ; DGGFCEVCK(1)K;DGGFCEVCK(1)K 132.78 0.00036244 8161200 1429.37 1788.03 1451.24 1584.07 2645 3710.5 2799.1 2794.6 3803.5 1542.85 FALSE TRUE FALSE 1316.233856 1942.579346 1505.024231 1577.515538 2613.460103 2940.900474 2877.635213 3646.660675 3386.265566 1596.463923 0.824468275 1.216801281 0.942723609 0.988131029 1.637030481 1.842134001 1.802505632 2.284211139 2.12110372 1 10.64066424 -5.485064777 1.15888129 0.930721341 2.087409441 0.358358789 0.406522441 0.109929134 0.275552385 0.024388776 0.089230481 3.27E-06 5.485064777 1.1566881 SAEALGPGALVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SAEALGPGALVSPR 14 0 Q9P227-2;Q9P227 Q9P227-2 ARHGAP23 Rho GTPase-activating protein 23 1 0 SAEALGPGALVS(1)PR 145.94 2.76E-05 0 1169.3 829.52 1100.6 1023.5 1068.4 1059.4 389.24 265.91 952.89 871.25 TRUE FALSE FALSE 1076.748671 901.2200125 1141.389204 1019.265028 1055.660028 839.6684981 400.1610268 346.9847349 848.360351 901.5258726 1.194362473 0.999660731 1.266063725 1.130599863 1.170970307 0.931385913 0.443870818 0.384886053 0.941027182 1 9.816225086 -4.823008384 2.978447504 1.106961991 0.384535468 0.891083506 0.094610113 0.053385633 0.937100751 0.013262765 0.052761232 1.50E-05 4.823008384 -0.722426523 down DGGQTES(ph)NEEGKENR ddPTM_HeLa_Curcumin_4h_R1 2 DGGQTESNEEGKENR 15 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5;Q5VU81;Q5VU80;Q5VU79;Q5VU78;Q5VU77 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 0 DGGQT(0.002)ES(0.998)NEEGKENR;DGGQT(0.002)ES(0.998)NEEGKENR ; 80.459 0.0067556 41207000 6027.1 5512.7 5932.5 5950.1 5716 5696.7 4879.5 2869.6 6483.2 6637.6 TRUE FALSE FALSE 5550.048675 5989.193224 6152.363669 5925.480063 5647.840433 4515.140205 5016.405637 3744.52783 5772.00918 6868.256106 0.80807247 0.87201076 0.895767947 0.862734291 0.822310692 0.657392522 0.730375449 0.54519339 0.840389335 1 12.74572812 -2.844356037 0.218416964 0.965303754 2.84E-32 0.714954305 0.065493365 9.342730787 0.224050772 0.05987896 2.709880064 0.001431014 2.844356037 -0.965303754 GQSQLSNPT(ph)DDSWK ddPTM_HeLa_Curcumin_4h_R1 1 GQSQLSNPTDDSWK 14 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 0 GQSQLS(0.007)NPT(0.993)DDSWK 128.06 0.0033497 16650000 3126.4 2833.2 3430 2932.9 2491.5 2968.5 1568.9 935.95 3362.7 3284.5 TRUE FALSE FALSE 2878.942141 3078.089184 3557.118817 2920.764437 2461.79049 2352.799638 1612.919112 1221.316846 2993.820223 3398.636131 0.847087488 0.905683652 1.046631261 0.859393099 0.724346589 0.692277592 0.474578345 0.359354988 0.880888718 1 11.7307402 -4.819997939 0.81817872 0.934603321 0.2378842 0.907561804 0.063577715 0.304892802 0.236783811 0.012462117 0.160973601 1.51E-05 4.819997939 -0.696719121 down DGGS(ph)GNSTIIVSR ddPTM_HeLa_Curcumin_4h_R1 3 DGGSGNSTIIVSR 13 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 DGGS(0.592)GNS(0.359)T(0.049)IIVSR;DGGS(0.995)GNS(0.004)T(0.001)IIVSR;DGGS(0.913)GNS(0.084)T(0.004)IIVSR ;; 142.95 0.00086355 166048000 4607.1 3856.8 3798.4 3811.4 3842 4843.5 3727.7 3003.23 4089.2 3362.38 TRUE FALSE FALSE 4242.443174 4190.164606 3939.172045 3795.629437 3796.186659 3838.903503 3832.289229 3918.901002 3640.624991 3479.222455 1.219365312 1.204339378 1.13219896 1.090941866 1.091102023 1.103379721 1.101478643 1.126372646 1.046390404 1 11.76454921 -9.55723138 1.357661209 1.000723461 1.142317961 0.476170796 0.04495495 0.291092795 0.969230821 0.037132591 0.008955431 2.77E-10 9.55723138 0.1415945 DGGSGNS(ph)TIIVSR ddPTM_HeLa_Curcumin_4h_R1 3 DGGSGNSTIIVSR 13 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 DGGS(0.032)GNS(0.888)T(0.08)IIVSR;DGGS(0.303)GNS(0.676)T(0.021)IIVSR;DGGS(0.193)GNS(0.78)T(0.028)IIVSR ;; 146.1 0.00072475 23417200 3893.4 3449.24 3977 4525.8 3983.8 5530.1 3828.2 3060.37 4452.6 3952.51 TRUE FALSE FALSE 3585.233282 3747.376936 4124.391119 4507.073439 3936.295787 4383.094923 3935.608989 3993.462725 3964.16092 4089.859428 0.876615283 0.916260571 1.008443246 1.102011822 0.962452587 1.071698184 0.96228466 0.976430314 0.969265812 1 11.99783554 -6.711727556 7.72516508 0.938220382 1.016115292 0.32349546 0.051888278 0.242255733 32.2338601 0.009678522 0.013658868 1.94E-07 6.711727556 0.07789491 DGGSGNSTIIVS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 DGGSGNSTIIVSR 13 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 DGGSGNSTIIVS(1)R 95.195 0.009506 5182600 1236.1 1169.4 1066.9 919.34 1070.9 1145.3 1010.4 2986.8 1141.1 1120 TRUE FALSE FALSE 1138.261381 1270.477725 1106.440253 915.5360147 1058.130217 907.7518698 1038.749105 3897.46157 1015.924185 1158.919917 0.98217432 1.096260153 0.954716747 0.78999075 0.913031351 0.783274027 0.896307924 3.363011986 0.876612931 1 10.17856516 -4.260538758 24.9999878 0.958619207 3.36301274 0.982905942 0.096485762 6.929038116 192309.3977 0.014056836 0.114079844 5.49E-05 4.260538758 2.404393533 TLSPTPAS(ph)ATAPTSQGIPTSDEESTPKK ddPTM_HeLa_Curcumin_4h_R1 1 TLSPTPASATAPTSQGIPTSDEESTPKK 28 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 T(0.064)LS(0.231)PT(0.31)PAS(0.359)AT(0.032)APT(0.002)S(0.002)QGIPTSDEESTPKK 76.41 3.57E-05 19199000 4335.7 3571.3 3717.1 3874.3 3533.7 3837.3 2224.9 1461.9 4993.1 3876.3 TRUE FALSE FALSE 3992.52477 3879.987259 3854.858996 3858.269173 3491.562935 3041.400725 2287.324706 1907.62658 4445.369422 4011.001136 0.995393577 0.967336365 0.961071529 0.961921735 0.870496621 0.758264738 0.570262792 0.475598614 1.108294232 1 11.96974666 -4.81753514 0.887148935 0.995426835 0.369338036 0.96089049 0.038214883 0.051580828 0.049241785 0.002141464 0.025880572 1.52E-05 4.81753514 -0.6260888 down DGLAFNALIHR ddPTM_HeLa_Curcumin_4h_R1 4 DGLAFNALIHR 11 0 O43707;M0QZQ3;C9JY79;Q9H254-2;Q9H254-4;Q9H254 O43707 ACTN4;SPTBN4 "Alpha-actinin-4;Spectrin beta chain, non-erythrocytic 4" 0 0 ;;; ;;; 186.87 2.28E-06 39654800 19050.6 14573 18132 15612.3 21063.3 31053.4 22637.8 21755 14991.9 15425.5 FALSE FALSE TRUE 17542.72491 15832.62518 18803.98787 15547.70044 20812.1339 24612.5748 23272.95574 28387.99935 13347.32608 15961.53498 1.099062523 0.991923722 1.178081425 0.974073011 1.303893011 1.541992974 1.458065015 1.778525649 0.836218202 1 13.96231178 -5.31087833 1.29025968 1.045475311 1.657699481 0.838330196 0.113993434 0.11364031 0.345261763 0.013510358 0.054383903 4.89E-06 5.31087833 0.61222417 DGLAPEKTS(ph)PDRDK ddPTM_HeLa_Curcumin_4h_R1 1 DGLAPEKTSPDRDK 14 2 Q7L4I2;E9PI52 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 0 DGLAPEKT(0.223)S(0.777)PDRDK 84.94 0.010536 35641000 2569.7 2326.2 2547.2 2368.5 3264.8 2741.7 2310.3 2199.6 2351.7 2089.2 TRUE FALSE FALSE 2366.305533 2527.266363 2641.601473 2358.699775 3225.869392 2173.040515 2375.1208 2870.247914 2093.724394 2161.799544 1.094599885 1.169056756 1.221945614 1.091081632 1.492214854 1.005199821 1.09867763 1.327712332 0.968509962 1 11.07801704 -7.660078504 0.779042672 1.017622382 1.20492192 0.305117718 0.129063749 0.53153067 0.694166815 0.035396763 0.032650515 2.19E-08 7.660078504 0.187299538 DGLGFCALIHR ddPTM_HeLa_Curcumin_4h_R1 4 DGLGFCALIHR 11 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;G3V2N5;G3V2W4;G3V2X9 P12814-4 ACTN1 Alpha-actinin-1 0 0 ;;; ;;; 138.25 0.0012853 23809500 12039.61 8844.35 12699.9 9402.62 11841.17 24599.3 15581.5 16311.2 9729.21 10132.85 FALSE FALSE TRUE 11086.66216 9608.816204 13170.56947 9363.71445 11699.97178 19497.12789 16018.67495 21284.40979 8661.940004 10484.96578 1.057386585 0.916437536 1.256138526 0.89306104 1.115880779 1.859531857 1.527775606 2.029993252 0.826129544 1 13.35603453 -5.307172859 5.276969847 1.029260458 1.779393156 0.835147746 0.162052742 0.047607358 3.233089736 0.018623483 0.043249899 4.93E-06 5.307172859 0.750132698 DGLILTSR ddPTM_HeLa_Curcumin_4h_R1 1 DGLILTSR 8 0 Q99497;K7ELW0;K7EN27 Q99497 PARK7 Protein deglycase DJ-1 0 0 141.52 0.00059335 6916800 3807.6 2546.2 3376.5 3359.7 3394.3 4167.2 3645 3403.2 3530.4 3422.7 FALSE FALSE TRUE 3506.224442 2766.282182 3501.63606 3345.798452 3353.825189 3302.875746 3747.26889 4440.820014 3143.123953 3541.63857 0.990000637 0.781074107 0.988705084 0.944703528 0.946969919 0.93258408 1.058060786 1.253888539 0.887477333 1 11.79020127 -4.338476641 2.675389216 0.969151576 1.28577559 0.651592939 0.068422819 0.18739189 1.942688025 0.00933153 0.120448325 4.59E-05 4.338476641 0.316624014 DGLNDDDFEPYLS(ph)PQAR ddPTM_HeLa_Curcumin_4h_R1 2 DGLNDDDFEPYLSPQAR 17 0 Q9Y5A9;S4R3J8 Q9Y5A9 YTHDF2 YTH domain-containing family protein 2 1 0 DGLNDDDFEPYLS(1)PQAR;DGLNDDDFEPYLS(1)PQAR ; 266.99 3.45E-52 52794000 2217.3 1917.94 1894.39 2305.5 2644.6 15204.1 4822.1 3525.7 2112.64 1854.28 TRUE FALSE FALSE 2041.798365 2083.718187 1964.59776 2295.960452 2613.064872 12050.59827 4957.395148 4600.6697 1880.888678 1918.716092 1.064148247 1.085996097 1.023912692 1.196612913 1.361881981 6.280553087 2.583704368 2.397785539 0.980285038 1 10.90592554 -5.487630008 24.84164304 1.054852603 3.667689949 0.605881776 0.982110709 265.0983797 186828.574 0.129306567 0.289013954 3.25E-06 5.487630008 2.612837346 DGLNQTTIPVS(ph)PPS(ph)TTKPSR ddPTM_HeLa_Curcumin_4h_R1 1 DGLNQTTIPVSPPSTTKPSR 20 1 X6RLN4;Q71RC2-2;Q71RC2-6;Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4 X6RLN4 LARP4 La-related protein 4 2 0 DGLNQT(0.002)T(0.002)IPVS(0.996)PPS(0.729)T(0.121)T(0.099)KPS(0.051)R 102.78 0.00028958 5217800 1043.1 1136.6 1032.2 1043 1455 1796.7 1629.5 767.39 1084.5 840.31 TRUE FALSE FALSE 960.5375343 1234.842639 1070.45424 1038.684342 1437.650075 1424.044167 1675.219384 1001.363678 965.5330633 869.51071 1.10468741 1.420158056 1.231099546 1.194561873 1.653401228 1.637753452 1.92662306 1.151640419 1.110432629 1 9.764059987 -6.493188826 0.601612322 1.023393711 1.635825146 0.444140722 0.21472913 0.429975594 0.312939263 0.050622664 0.111482921 3.21E-07 6.493188826 0.612431435 DGLNQTTIPVS(ph)PPSTTKPSR ddPTM_HeLa_Curcumin_4h_R1 3 DGLNQTTIPVSPPSTTKPSR 20 1 X6RLN4;Q71RC2-2;Q71RC2-6;Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4 X6RLN4 LARP4 La-related protein 4 1 0 DGLNQTTIPVS(0.998)PPSTTKPS(0.001)R;DGLNQTTIPVS(0.993)PPS(0.002)T(0.002)T(0.002)KPSR;DGLNQTTIPVS(0.981)PPS(0.013)T(0.003)T(0.003)KPSR ;; 152.57 8.69E-06 598070000 5532.9 4432.63 4966.7 5584 5044.98 5157.1 5013.4 4915 5229.6 4450.8 TRUE FALSE FALSE 5094.965127 4815.766786 5150.770271 5560.894888 4984.821908 4087.459328 5154.062511 6413.560874 4655.925964 4605.464969 1.106286805 1.045663536 1.118403963 1.207455691 1.08237104 0.887523704 1.119118818 1.392597907 1.010956765 1 12.1691311 DGLPRTPS(ph)RR ddPTM_HeLa_Curcumin_4h_R1 1 DGLPRTPSRR 10 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 DGLPRT(0.146)PS(0.854)RR 51.445 0.019531 15641000 1964.2 2042.1 1872.9 2075.6 1818.1 2077 2194.5 1613.6 2248.3 1965.9 TRUE FALSE FALSE 1808.731497 2218.610025 1942.311322 2067.011717 1796.420345 1646.206787 2256.071764 2105.579212 2001.667115 2034.214879 0.88915459 1.090646838 0.954821116 1.016122603 0.883102549 0.809259044 1.10906266 1.035082003 0.98399984 1 10.99025637 DGLQNEK(ac)NIVSTPVK ddPTM_HeLa_Curcumin_4h_R1 2 DGLQNEKNIVSTPVK 15 1 P35914-3;P35914-2;P35914 P35914-3 HMGCL "Hydroxymethylglutaryl-CoA lyase, mitochondrial" 0 1 ; DGLQNEK(1)NIVSTPVK;DGLQNEK(1)NIVSTPVK 296.22 2.01E-112 9137100 3556.5 2394.67 2694.29 3259.9 3063.8 4114.2 2667.51 2629.1 3371.9 2517.39 FALSE TRUE FALSE 3274.999272 2601.654604 2794.142758 3246.411398 3027.266186 3260.868543 2742.353151 3430.700487 3002.011006 2604.869115 1.257260587 0.998765961 1.072661479 1.246285803 1.162156735 1.25183585 1.052779633 1.31703373 1.152461361 1 11.34699517 -6.265943149 24.92216647 1.110084974 1.197613749 0.240187858 0.095483938 633.644111 3506352.574 0.017743495 0.027679151 5.42E-07 6.265943149 0.087528775 DGMDNQGGYGS(ph)VGR ddPTM_HeLa_Curcumin_4h_R1 3 DGMDNQGGYGSVGR 14 0 P31942;P31942-3;P31942-2;P31942-4 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 1 0 DGMDNQGGYGS(1)VGR;DGMDNQGGYGS(1)VGR;DGMDNQGGYGS(1)VGR ;; 201.4 6.41E-09 41561700 4878.7 3964.3 4643.8 4999 4551.4 6737.5 4521.6 9318.5 4611.6 4306.5 TRUE FALSE FALSE 4492.545747 4306.956427 4815.903313 4978.315463 4497.127528 5340.066553 4648.463927 12159.66775 4105.719018 4456.150554 1.008167406 0.966519505 1.080731733 1.117178471 1.009195599 1.198358648 1.043156839 2.72873809 0.921360032 1 12.12158226 -4.261234921 7.627882117 1.028827285 2.746040456 0.978564688 0.075048185 0.00892243 5.259764648 0.009730758 0.07813229 5.48E-05 4.261234921 1.717213171 DGMDNQGGYGSVGR ddPTM_HeLa_Curcumin_4h_R1 4 DGMDNQGGYGSVGR 14 0 P31942;P31942-3;P31942-2;P31942-4 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 0 ;;; ;;; 198.52 6.08E-13 139824000 4440.73 3910.89 3727.31 3662.68 4019.65 5478.2 4075.93 3444.23 4439.68 4060.98 FALSE FALSE TRUE 4089.241535 4248.929905 3865.447387 3647.524801 3971.718299 4341.959568 4190.289626 4494.359872 3952.658212 4202.098753 0.973142654 1.011144705 0.919884947 0.868024531 0.945174907 1.033283562 0.997189707 1.069551226 0.940639058 1 12.03689435 -4.382850076 1.385049992 0.973730489 1.087733193 0.329937618 0.045803079 1.136310706 2.252936978 0.007251062 0.168523013 4.14E-05 4.382850076 0.114002704 DGMEYPFIGEGEPHVDGEPGDLR ddPTM_HeLa_Curcumin_4h_R1 3 DGMEYPFIGEGEPHVDGEPGDLR 23 0 H7C2Y5;Q9UBS4 H7C2Y5 DNAJB11 DnaJ homolog subfamily B member 11 0 0 ;; ;; 164.18 7.80E-09 8837300 5969.5 4590.5 5673.6 5238.03 6147.8 6491 4484.9 3705 5149.3 4670.26 FALSE FALSE TRUE 5497.007776 4987.282365 5883.868607 5216.35642 6074.4915 5144.693431 4610.734224 4834.637444 4584.434673 4832.551187 1.137496027 1.032018528 1.217549153 1.079420831 1.256994756 1.064591606 0.954099407 1.000431709 0.94865724 1 12.2385693 -4.858914854 5.64372092 1.09015913 0.978248492 0.213796376 0.088997014 0.229317173 10.81185125 0.012137973 0.037900117 1.38E-05 4.858914854 -0.111910638 DGNIYS(ph)GLPDYSVSFLGK ddPTM_HeLa_Curcumin_4h_R1 1 DGNIYSGLPDYSVSFLGK 18 0 Q5TCS8-1;J3KP89;Q5TCS8-2;Q5TCS8-3;Q5TCS8-6;Q5TCS8 Q5TCS8-1 AK9 Adenylate kinase 9 1 0 DGNIY(0.035)S(0.965)GLPDYSVSFLGK 61.942 0.011936 4567800 4667.5 829.89 832.62 1250.6 2362.4 9312.6 2216.5 559.26 1292 810.49 TRUE FALSE FALSE 4298.06245 901.6219937 863.4776296 1245.425349 2334.229923 7381.061785 2278.689025 729.7757995 1150.270832 838.6544672 5.124950284 1.075081609 1.029598796 1.485027979 2.783303511 8.801076098 2.717077311 0.870174581 1.371567049 1 9.71193272 -9.684919472 1.559958621 1.001909533 3.332170127 0.072635932 2.318513465 0.735623941 3.229476782 1.746339294 0.389567057 2.07E-10 9.684919472 2.330260594 DGPEETDWWWAALHGQEGYVPR ddPTM_HeLa_Curcumin_4h_R1 2 DGPEETDWWWAALHGQEGYVPR 22 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 0 0 ; ; 127.5 8.51E-06 12087600 2474.19 2141.23 2212.57 2160.55 2278.68 3248.2 2585.69 2449.83 2779.1 2279.19 FALSE FALSE TRUE 2278.355251 2326.30838 2294.569791 2151.610217 2251.508229 2574.486705 2658.237502 3196.771889 2474.239683 2358.391683 0.96606313 0.986396109 0.972938383 0.912320982 0.954679516 1.091628131 1.127139958 1.355488112 1.049121612 1 11.20358763 -4.222795854 1.156850441 0.976496815 1.552890412 0.893185461 0.039742331 0.329768045 0.336441835 0.005222397 0.23404813 5.99E-05 4.222795854 0.576393596 DGPGLERS(ph)PGEPGGAAPER ddPTM_HeLa_Curcumin_4h_R1 2 DGPGLERSPGEPGGAAPER 19 1 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 0 DGPGLERS(1)PGEPGGAAPER;DGPGLERS(1)PGEPGGAAPER ; 73.675 0.0034704 25016000 3756.2 2926.69 2981.62 3206.4 2708.97 3553.1 3043.8 2833.15 3697.7 2600.51 TRUE FALSE FALSE 3458.892806 3179.660043 3092.12146 3193.132766 2676.667302 2816.147008 3129.200836 3696.964393 3292.071561 2690.877529 1.285414431 1.181644281 1.149112669 1.186651095 0.99471911 1.046553393 1.162892329 1.373888017 1.223419322 1 11.39386102 -9.590992569 1.400815499 1.000569653 1.179043018 0 0.121712412 0.460673091 1.62981414 0.076311765 0.01796603 2.56E-10 9.590992569 0.178473365 DGPS(ph)SAPAT(ph)PTKAPYS(ph)PTTSK ddPTM_HeLa_Curcumin_4h_R1 1 DGPSSAPATPTKAPYSPTTSK 21 1 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 3 0 DGPS(0.582)S(0.571)APAT(0.849)PT(0.174)KAPY(0.077)S(0.557)PT(0.128)T(0.034)S(0.029)K 60.951 0.0088212 9490100 1617.9 1477.5 1857.4 1691 1778.9 2140.1 1660.6 1076.2 1929.9 1787 TRUE FALSE FALSE 1489.841508 1605.208516 1926.236878 1684.00309 1757.687779 1696.219136 1707.191967 1404.328426 1718.194798 1849.098117 0.805712522 0.868103483 1.041716965 0.910715919 0.950564907 0.917322407 0.92325656 0.75946669 0.929206937 1 10.85260606 -9.674039008 1.549887619 0.999707328 0.888935334 0.078547804 0.076180302 0.498208214 2.164042575 0.055702572 0.012590682 2.12E-10 9.674039008 -0.110771994 DGPSS(ph)APATPTK ddPTM_HeLa_Curcumin_4h_R1 2 DGPSSAPATPTK 12 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 0 DGPS(0.046)S(0.954)APAT(0.001)PTK;DGPS(0.061)S(0.939)APATPTK ; 196.15 2.51E-06 35783000 9458.6 8948.7 9107.3 8802.5 9739.2 9280.2 7351.8 5973.1 7767.6 7868.1 TRUE FALSE FALSE 8709.941829 9722.185753 9444.82455 8766.077587 9623.066401 7355.381911 7558.071722 7794.270693 6915.513714 8141.515889 1.069818195 1.194149331 1.160081817 1.076713195 1.181974774 0.903441326 0.928337158 0.957348828 0.849413525 1 12.99108172 -5.235027049 24.75273921 1.067815951 0.929571885 0.327504748 0.095573555 541.2636346 507252.9664 0.011278098 0.028744347 5.82E-06 5.235027049 -0.138244066 DGPSSAPATPTKAPYS(ph)PTTSK ddPTM_HeLa_Curcumin_4h_R1 2 DGPSSAPATPTKAPYSPTTSK 21 1 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 0 DGPSSAPAT(0.038)PT(0.291)KAPY(0.183)S(0.368)PT(0.092)T(0.023)S(0.006)K;DGPSSAPAT(0.003)PT(0.114)KAPY(0.269)S(0.324)PT(0.195)T(0.07)S(0.025)K ; 103.41 3.37E-05 29152000 7273.4 5897.4 6058.6 6685.3 5837.1 6896.9 3626 2822.2 8532.5 6696.7 TRUE FALSE FALSE 6697.702715 6407.144978 6283.137046 6657.638 5767.496395 5466.405196 3727.735801 3682.675788 7596.506097 6929.409827 0.966561783 0.924630688 0.906734802 0.960779946 0.832321444 0.78887024 0.537958628 0.531455908 1.096270287 1 12.75851677 -4.81142651 0.786590953 0.978815603 0.385260406 0.907377513 0.054482557 0.19940155 0.139234887 0.006461267 0.087477992 1.54E-05 4.81142651 -0.593555197 DGQAMLWDLNEGK ddPTM_HeLa_Curcumin_4h_R1 2 DGQAMLWDLNEGK 13 0 P63244;D6RAC2;D6REE5;D6R9L0;J3KPE3;D6RFX4;D6R9Z1;H0YAF8;H0Y8W2;H0Y8R5;H0YAM7 P63244 GNB2L1 "Guanine nucleotide-binding protein subunit beta-2-like 1;Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed" 0 0 ; ; 205.31 2.97E-08 86237000 3959.5 3319.3 3370.9 3248.8 3577.9 6051 3825.1 3430.5 3247.1 3383.4 FALSE FALSE TRUE 3646.101397 3606.205501 3495.828519 3235.357326 3535.235879 4795.954391 3932.422011 4476.443658 2890.901254 3500.972898 1.041453762 1.030058103 0.998530586 0.924130926 1.009786703 1.369891893 1.123236919 1.278628481 0.825742254 1 11.77354018 -5.282603194 24.53727211 1.011277033 1.24385087 0.676220657 0.086727378 210.5502733 244111.1387 0.008539168 0.019113271 5.22E-06 5.282603194 0.232573838 DGQDAIAQS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 1 DGQDAIAQSPEK 12 0 Q9NWH9;H0YL55;H7BXE3 Q9NWH9 SLTM SAFB-like transcription modulator 1 0 DGQDAIAQS(1)PEK 158.91 0.00025051 43190000 3903.1 3602.5 3897.2 3822 4729.1 4376.8 3978.9 3449.6 3110.8 3079.3 TRUE FALSE FALSE 3594.165516 3913.884048 4041.63366 3806.185577 4672.708571 3469.002343 4090.537225 4501.36716 2769.553023 3186.305446 1.128004072 1.228345529 1.268438864 1.194545106 1.466497375 1.088722473 1.283786911 1.412723054 0.869205125 1 11.63766886 -7.570915844 0.489629595 1.002485995 1.308985894 0.605484658 0.107961631 0.423336439 0.252470465 0.044484078 0.0399319 2.69E-08 7.570915844 0.306499898 DGQDAIAQS(ph)PEKESK ddPTM_HeLa_Curcumin_4h_R1 4 DGQDAIAQSPEKESK 15 1 Q9NWH9;H0YL55;H7BXE3 Q9NWH9 SLTM SAFB-like transcription modulator 1 0 DGQDAIAQS(0.999)PEKES(0.001)K;DGQDAIAQS(0.998)PEKES(0.002)K;DGQDAIAQS(0.997)PEKES(0.003)K;DGQDAIAQS(0.977)PEKES(0.023)K ;;; 76.329 0.0088228 1576243000 14063.8 11587.5 15646.6 15060.5 16174.3 16812.3 15032.4 11471.4 14356.7 12068.8 TRUE FALSE FALSE 12950.63539 12589.07187 16226.47676 14998.18364 15981.43204 13325.23947 15454.16869 14968.97705 12781.80593 12488.1899 1.037030626 1.00807819 1.299345773 1.200989396 1.279723656 1.067027293 1.237502697 1.198650659 1.023511496 1 13.60827676 -6.77661603 24.99354511 1.017269623 1.210680064 0.725965753 0.059190387 87.82323729 144630.6699 0.009102648 0.011989 1.67E-07 6.77661603 0.193410441 SST(ph)PLHS(ph)PSPIR ddPTM_HeLa_Curcumin_4h_R1 1 SSTPLHSPSPIR 12 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 2 0 S(0.041)S(0.053)T(0.906)PLHS(0.846)PS(0.154)PIR 86.772 0.018524 117070000 3921.5 2750.9 3331.4 3281.8 4426.4 3094.5 1623.2 744.25 3641.8 2720.2 TRUE FALSE FALSE 3611.109137 2988.675538 3454.864615 3268.220781 4373.618071 2452.665818 1668.742623 971.1683989 3242.303651 2814.726748 1.282934175 1.06179953 1.227424516 1.161114763 1.553833982 0.871369066 0.592861323 0.345031147 1.151907074 1 11.45877916 -4.814531997 2.66458914 1.165331238 0.415024468 0.783377821 0.154117914 0.102027927 1.423792687 0.023801895 0.102062954 1.53E-05 4.814531997 -0.75030677 down DGQSS(ph)PQPSPR ddPTM_HeLa_Curcumin_4h_R1 1 DGQSSPQPSPR 11 0 Q5VZK9;Q5VZK9-2;A0A0U1RQQ1 Q5VZK9 LRRC16A Leucine-rich repeat-containing protein 16A 1 0 DGQS(0.217)S(0.783)PQPSPR 115.83 0.0047427 44081000 5537.5 4381.5 5215 4868.4 5215.3 4048.6 2791.3 2301.5 5405.1 4878.2 TRUE FALSE FALSE 5099.201032 4760.217336 5408.272488 4848.255851 5153.110954 3208.874723 2869.616366 3003.216755 4812.174053 5047.717087 1.010199451 0.943043609 1.0714294 0.960484862 1.020879511 0.635708117 0.568497861 0.594965348 0.95333672 1 12.30141534 -5.223837 4.708473469 1.003242794 0.588546131 0.957881504 0.037923305 0.021545775 1.165557604 0.004331986 0.011181031 5.97E-06 5.223837 -0.414696664 DGQVINETS(ph)QHHDDLE ddPTM_HeLa_Curcumin_4h_R1 4 DGQVINETSQHHDDLE 16 0 P08670 P08670 VIM Vimentin 1 0 DGQVINET(0.084)S(0.916)QHHDDLE;DGQVINET(0.241)S(0.759)QHHDDLE;DGQVINET(0.205)S(0.795)QHHDDLE;DGQVINET(0.231)S(0.769)QHHDDLE ;;; 142.84 0.00018108 38070200 10712.4 8973.79 9123.35 10479.5 9761.04 16242.2 15402.5 7436.59 11696.3 9628.41 TRUE FALSE FALSE 9864.502236 9749.444421 9461.469377 10436.13861 9644.645973 12873.38463 15834.6527 9703.972057 10413.24515 9962.996531 0.990113989 0.978565474 0.949661013 1.047489937 0.968046706 1.292119755 1.589346403 0.974001349 1.045192089 1 13.28236401 -5.24119186 7.213781513 0.992797433 1.316949471 0.460352317 0.141705651 0.09981704 24.93671388 0.017340213 0.043273573 5.74E-06 5.24119186 0.324152038 DGQVINETSQHHDDLE ddPTM_HeLa_Curcumin_4h_R1 9 DGQVINETSQHHDDLE 16 0 P08670 P08670 VIM Vimentin 0 0 ;;;;;;;; ;;;;;;;; 151.49 0.00019151 297704100 39337 32314.6 34073.4 34098.1 44797.1 66817.9 38030.6 35619 45447.8 37809.5 FALSE FALSE TRUE 36223.43494 35107.73003 35336.19018 33957.0111 44262.92384 52959.11435 39097.63628 46479.06913 40462.29004 39123.37731 0.925876993 0.897359391 0.90319887 0.867946824 1.13136766 1.353643729 0.999342055 1.1880127 1.034222831 1 15.2557433 -5.65249491 6.055570479 0.947616745 1.174375189 0.600513696 0.0921625 0.109885939 5.494916631 0.012756875 0.025692321 2.23E-06 5.65249491 0.226758444 DGQWFTDWDAVPHSR ddPTM_HeLa_Curcumin_4h_R1 2 DGQWFTDWDAVPHSR 15 0 Q08J23-2;Q08J23;Q08J23-3 Q08J23-2 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 0 0 ; ; 141.1 0.00042268 106182000 14037.8 11579 11731.5 12121.2 11787.4 14833.9 11171.7 8883.7 14018.1 12828.5 FALSE FALSE TRUE 12926.69332 12579.83716 12166.27971 12071.04569 11646.84295 11757.18193 11485.14783 11592.29923 12480.3495 13274.28942 0.973814334 0.947684412 0.91652964 0.909355319 0.8773986 0.885710832 0.865217525 0.873289625 0.940189648 1 13.69634701 -6.669198713 0.630613352 0.995004737 0.866669771 0.819403282 0.018405182 0.062091234 0.050649209 0.001726132 0.003229985 2.14E-07 6.669198713 -0.128334966 DGRHPQGEQMYR ddPTM_HeLa_Curcumin_4h_R1 5 DGRHPQGEQMYR 12 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ;;;; ;;;; 98.754 0.0028256 17518780 8491.2 7293.322 6231.3 8239.684 6158.8 7257.19 6412.2 5532.31 9846.6 7956.9 FALSE FALSE TRUE 7819.11256 7923.724255 6462.23746 8205.590371 6085.360332 5751.966989 6592.109074 7219.085851 8766.452615 8233.401683 0.949681901 0.962387669 0.784880625 0.996622136 0.739106455 0.698613673 0.800654375 0.876804768 1.064742491 1 13.0072729 -6.533285492 0.744867525 0.984111439 0.782426615 0.533476202 0.081202305 0.365737347 0.406589822 0.016192357 0.031885872 2.93E-07 6.533285492 -0.201684824 DGS(ph)GDSHPDFPEDADIDLKDVDK ddPTM_HeLa_Curcumin_4h_R1 1 DGSGDSHPDFPEDADIDLKDVDK 23 1 Q08752 Q08752 PPID Peptidyl-prolyl cis-trans isomerase D 1 0 DGS(0.984)GDS(0.016)HPDFPEDADIDLKDVDK 61.976 0.0022912 4209200 1692.3 1526.9 1972.9 1618.7 1704.6 1694.5 2019.8 1906.2 1775.8 1687.9 TRUE FALSE FALSE 1558.352669 1658.878432 2046.01741 1612.002248 1684.273758 1343.041599 2076.470152 2487.391605 1580.999183 1746.554399 0.892243992 0.949800609 1.171459309 0.922961374 0.964340852 0.768966371 1.188895206 1.424170702 0.905210386 1 10.77029586 -4.527946695 4.763498297 0.953547308 1.381449127 0.711090436 0.096924149 0.067781067 4.123219811 0.013356142 0.063416864 2.97E-05 4.527946695 0.42790182 DGS(ph)PEAPAS(ph)PEREEVALSEYK ddPTM_HeLa_Curcumin_4h_R1 2 DGSPEAPASPEREEVALSEYK 21 1 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 2 0 DGS(1)PEAPAS(0.998)PEREEVALS(0.002)EYK;DGS(1)PEAPAS(0.999)PEREEVALS(0.001)EYK ; 93.229 0.00027525 173813000 15473.9 15171.7 16683.4 14123.4 18292.7 16403.6 15169.7 16191.7 13492.1 12647.5 TRUE FALSE FALSE 14249.12449 16483.07414 17301.70148 14064.96111 18074.5715 13001.30845 15595.32095 21128.47479 12012.05039 13086.99968 1.088799941 1.25949985 1.322052563 1.074727703 1.381108882 0.993452187 1.191665113 1.614462849 0.917861288 1 13.67584676 -1 0.112874161 0.888552776 2.356308809 0.408177156 0.155954466 82.11899646 0.646123295 0.820863606 18.89974989 0.1 1 1.467756033 DGSASAAAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 DGSASAAAKK 10 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2;Q68E03 A0A0R4J2E8 MATR3;DKFZp686L22104 Matrin-3 0 1 ; DGSASAAAK(1)K;DGSASAAAK(1)K 104.22 0.0023933 3814000 2861.78 3167.72 2038.79 2369.3 2279.56 2686 1948.64 1773.74 2100.73 2528.04 FALSE TRUE FALSE 2635.267093 3441.523602 2114.349351 2359.496464 2252.377736 2128.893323 2003.313594 2314.545161 1870.285175 2615.889202 1.007407765 1.315622848 0.808271753 0.901986393 0.861037132 0.813831611 0.765825094 0.884802445 0.714971098 1 11.35308572 DGSASAAAK(ac)K(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 DGSASAAAKKK 11 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2;Q68E03 A0A0R4J2E8 MATR3;DKFZp686L22104 Matrin-3 0 2 DGSASAAAK(1)K(1)K 141.88 5.44E-05 1307300 889.39 830.71 755.73 783.89 593.6 1066.8 901.16 1155.1 890.4 763.46 FALSE TRUE FALSE 818.993843 902.5128708 783.7380186 780.6464709 586.5217077 845.5336547 926.4441243 1507.284673 792.7253477 789.9901782 1.036713956 1.142435559 0.992085776 0.988172375 0.742441772 1.070309072 1.172728662 1.907979003 1.003462283 1 9.625690906 -4.219794608 2.307861789 1.006052596 2.190243227 0.888446464 0.096559483 0.160786172 0.909606845 0.013650067 0.398320239 6.03E-05 4.219794608 1.184190631 DGSGGASGTLQPSSGGGSSNS(ph)RER ddPTM_HeLa_Curcumin_4h_R1 1 DGSGGASGTLQPSSGGGSSNSRER 24 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 0 DGSGGASGTLQPS(0.107)S(0.107)GGGS(0.181)S(0.181)NS(0.425)RER 63.703 0.0034048 0 1106.7 902.66 963.46 820.92 778.45 1273.2 762.97 279.09 1069.7 1235.8 TRUE FALSE FALSE 1019.103527 980.6819082 999.1666751 817.5232506 769.1674922 1009.123968 784.3768848 364.1832562 952.3565863 1278.743958 0.796956671 0.766910297 0.781365706 0.639317391 0.601502347 0.789152482 0.613396357 0.284797636 0.744759403 1 10.32051171 -4.462411168 0.156414354 1.086024495 1.52E-14 0.527881728 0.121696603 7.964080392 0.232125658 0.280686948 1.825615519 3.45E-05 4.462411168 -1.086024495 DGSIS(ph)PVSSECSVVER ddPTM_HeLa_Curcumin_4h_R1 1 DGSISPVSSECSVVER 16 0 H0YCZ0;H7BY22;H0YEM9;Q8NCP5-3;Q8NCP5-4;Q8NCP5-2;Q8NCP5 H0YCZ0 ZBTB44 Zinc finger and BTB domain-containing protein 44 1 0 DGS(0.011)IS(0.985)PVS(0.003)S(0.001)ECSVVER 221.34 1.50E-15 19961000 2097.4 1054 1671.3 1706 1579.1 1878 1302.7 1068.4 2005.9 1236.7 TRUE FALSE FALSE 1931.388577 1145.103063 1733.239848 1698.941024 1560.270264 1488.481631 1339.250256 1394.150242 1785.857789 1279.675233 1.509280267 0.894838811 1.354437285 1.327634528 1.219270502 1.163171399 1.046554799 1.089456298 1.395555484 1 10.321562 -4.987796256 2.832866024 1.233136889 1.067755849 0.139485724 0.172214907 0.523629794 8.435130733 0.030104703 0.103320251 1.03E-05 4.987796256 -0.16538104 EQTFSGGTS(ph)QDTK ddPTM_HeLa_Curcumin_4h_R1 1 EQTFSGGTSQDTK 13 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 EQTFS(0.001)GGT(0.223)S(0.73)QDT(0.047)K 127.07 0.0018546 20502000 3193.6 2561.7 3759.3 3233.2 4183.9 3617.5 4686 5417.3 3103.5 3051.6 TRUE FALSE FALSE 2940.82319 2783.121933 3898.622965 3219.821875 4134.009725 2867.189722 4817.476548 7069.009832 2763.053815 3157.642873 0.931334957 0.881392243 1.234662412 1.019691588 1.309207498 0.908015833 1.525655922 2.238698332 0.875036832 1 11.6246323 -4.366511256 1.972492612 1.001828623 2.465269047 0.870818793 0.145311107 0.136809805 0.663522045 0.019550524 0.333186507 4.30E-05 4.366511256 1.463440424 up DGSPEAPAS(ph)PEREEVALSEYK ddPTM_HeLa_Curcumin_4h_R1 2 DGSPEAPASPEREEVALSEYK 21 1 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 DGSPEAPAS(0.889)PEREEVALS(0.086)EY(0.024)K;DGS(0.001)PEAPAS(0.984)PEREEVALS(0.015)EYK ; 78.451 0.00056574 132627000 5543.2 4647.4 5434.9 4654.7 5784.4 5966.2 4891.6 7315.2 5306.2 4970.8 TRUE FALSE FALSE 5104.449871 5049.100548 5636.322175 4635.440085 5715.424808 4728.742867 5028.845131 9545.570805 4724.123135 5143.53493 0.992401129 0.981640179 1.095807115 0.901216799 1.111186156 0.919356616 0.977702144 1.855838627 0.918458453 1 12.32854449 -4.260648904 24.98190387 0.997219229 1.855838897 0.93780274 0.066966353 8.727038507 275755.6326 0.007305245 0.058936666 5.49E-05 4.260648904 0.858619668 DGSYAWEIKDFLVGQDR ddPTM_HeLa_Curcumin_4h_R1 2 DGSYAWEIKDFLVGQDR 17 1 Q14696 Q14696 MESDC2 LDLR chaperone MESD 0 0 ; ; 157.37 0.00014199 18562400 2439.75 1502.99 2023.59 2226.43 2323.33 2406.75 1931.05 2101.55 1861.16 1869.69 FALSE FALSE TRUE 2246.641213 1632.901758 2098.586026 2217.217623 2295.625807 1907.56292 1985.230066 2742.302921 1656.995404 1934.661588 1.161257983 0.844024489 1.08473029 1.146049333 1.186577446 0.985993071 1.026138151 1.417458711 0.856478164 1 10.91786552 -6.384906977 5.399450294 1.056847802 1.137580888 0.166404945 0.146985744 0.509654232 20.53590626 0.020973503 0.03221155 4.12E-07 6.384906977 0.080733085 DGTAPPPQSPGS(ph)PGTGQDEEWS(ph)DEESPRK ddPTM_HeLa_Curcumin_4h_R1 1 DGTAPPPQSPGSPGTGQDEEWSDEESPRK 29 1 A0A0C4DGG1;Q9UKS6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 2 0 DGT(0.002)APPPQS(0.134)PGS(0.694)PGT(0.417)GQDEEWS(0.731)DEES(0.022)PRK 40.718 0.017683 20076000 1031.6 600.31 892.34 814.65 919.33 993.49 706.14 1124.5 888.24 730.56 TRUE FALSE FALSE 949.9477715 652.1981215 925.4109054 811.2791942 908.3675902 787.4289751 725.9523879 1467.354873 790.8022943 755.9469056 1.256632925 0.86275652 1.224174474 1.073195998 1.201628823 1.041645874 0.960321925 1.941081923 1.04610825 1 9.562141099 -4.255504668 24.93017641 1.101899417 1.941082303 0.822982239 0.120009869 210.5906541 884609.8424 0.017652107 0.212853669 5.55E-05 4.255504668 0.839182885 DGTAPPPQSPGSPGT(ph)GQDEEWSDEESPRK ddPTM_HeLa_Curcumin_4h_R1 1 DGTAPPPQSPGSPGTGQDEEWSDEESPRK 29 1 A0A0C4DGG1;Q9UKS6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 0 DGTAPPPQS(0.005)PGS(0.014)PGT(0.79)GQDEEWS(0.189)DEES(0.002)PRK 73.435 6.89E-05 15722000 1111.2 971.3 929.83 1376 1138.3 1110.7 894.53 798.72 1232.8 1150.8 TRUE FALSE FALSE 1023.247347 1055.254844 964.2903178 1370.306477 1124.726516 880.3282998 919.6281043 1042.246051 1097.564924 1190.790214 0.859301105 0.886180312 0.80979026 1.150753894 0.944521128 0.739280764 0.772283895 0.875255808 0.921711407 1 10.21770356 -13.52287875 0.185005077 1.521073961 0.847563909 0.077121455 0.10864577 82.4940132 0.961528815 15.65467621 0.14457782 3.00E-14 13.52287875 -0.673510052 DGTAPPPQSPGSPGTGQDEEWS(ph)DEESPR ddPTM_HeLa_Curcumin_4h_R1 1 DGTAPPPQSPGSPGTGQDEEWSDEESPR 28 0 A0A0C4DGG1;Q9UKS6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 0 DGTAPPPQSPGSPGT(0.005)GQDEEWS(0.981)DEES(0.014)PR 98.683 3.65E-06 0 2275.6 2009.8 1920.3 1865 2345.5 2617.8 2008.8 1645.3 2035.6 2021.4 TRUE FALSE FALSE 2095.483859 2183.518157 1991.468007 1857.283124 2317.531444 2074.838771 2065.161522 2146.944396 1812.299773 2091.6435 1.001836049 1.043924625 0.952106804 0.887953958 1.107995433 0.991965778 0.987339153 1.026438968 0.866447735 1 11.03042126 -4.24320038 21.13610345 0.998847547 1.026439161 0 0.067931628 1586.238524 1837935.945 0.006856821 0.223226624 5.71E-05 4.24320038 0.027591613 DGTAPPPQSPGSPGTGQDEEWS(ph)DEESPRK ddPTM_HeLa_Curcumin_4h_R1 3 DGTAPPPQSPGSPGTGQDEEWSDEESPRK 29 1 A0A0C4DGG1;Q9UKS6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 0 DGTAPPPQS(0.002)PGS(0.011)PGT(0.096)GQDEEWS(0.886)DEES(0.005)PRK;DGTAPPPQS(0.001)PGS(0.002)PGT(0.238)GQDEEWS(0.753)DEES(0.007)PRK;DGTAPPPQS(0.003)PGS(0.01)PGT(0.223)GQDEEWS(0.76)DEES(0.005)PRK ;; 67.655 0.00012818 296186000 4998.7 4156.1 4563.8 4920.3 4740 5654.1 4448.9 3882.7 5582.2 4877.4 TRUE FALSE FALSE 4603.04762 4515.334765 4732.938443 4899.941102 4683.478596 4481.375925 4573.72416 5066.517356 4969.846626 5046.889287 0.912056389 0.894676801 0.937793198 0.970883414 0.927993132 0.887948134 0.906246185 1.003889142 0.984734624 1 12.30117872 -9.309595008 1.010034055 1.0004384 0.927544219 0.34742571 0.033697676 0.444652968 0.805087199 0.023356239 0.00608077 4.90E-10 9.309595008 -0.072894181 DGTGVVEFVR ddPTM_HeLa_Curcumin_4h_R1 1 DGTGVVEFVR 10 0 J3KTL2;Q07955;Q07955-3;Q07955-2;J3KSR8 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 0 134.77 0.019132 16268000 1827.1 1798.3 1488.9 1992.5 1588.1 2507.5 1722.1 1737.4 2044.2 1639.4 FALSE FALSE TRUE 1682.483107 1953.737039 1544.079944 1984.255563 1569.162945 1987.416235 1770.417491 2267.125262 1819.956374 1696.369028 0.991814328 1.151716995 0.910226441 1.169707493 0.925012729 1.171570691 1.043651153 1.336457589 1.072854046 1 10.72823433 -1 0.707140485 1.009029278 40.8942583 0.425751393 0.09454703 155.823687 0.750510846 0.013200801 9851.846248 0.1 1 39.88522902 DGTS(ph)PEEEIEIER ddPTM_HeLa_Curcumin_4h_R1 2 DGTSPEEEIEIER 13 0 Q9H501 Q9H501 ESF1 ESF1 homolog 1 0 DGT(0.033)S(0.967)PEEEIEIER;DGT(0.035)S(0.965)PEEEIEIER ; 139.19 0.0010372 22229000 2305.2 1774.76 1950.89 1902.71 2281.6 2518.4 2192.7 1769.12 2334.7 1929.53 TRUE FALSE FALSE 2122.740988 1928.162346 2023.1917 1894.83709 2254.39341 1996.055452 2254.221261 2308.516544 2078.589251 1996.581024 1.063188001 0.965732081 1.013328122 0.949040919 1.129126934 0.999736764 1.129040712 1.156234842 1.04107433 1 10.9633159 -4.490351793 1.231573219 1.022160368 1.198199434 0.47627138 0.049838501 0.679033262 1.138308573 0.007294288 0.135827411 3.23E-05 4.490351793 0.176039065 DGVCGPPPSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 DGVCGPPPSKK 11 1 Q08J23-2;Q08J23;Q08J23-3;A0A140T9Z1 Q08J23-2 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 0 1 ; DGVCGPPPSK(1)K;DGVCGPPPSK(1)K 134.75 0.00016707 21146000 7561.6 7240.3 7770.4 7066.8 9335.8 12127.5 7239.2 6416.7 9450.5 7038.1 FALSE TRUE FALSE 6963.091381 7866.11927 8058.37786 7037.559454 9224.476682 9612.119795 7442.312469 8373.122291 8413.803794 7282.673451 0.956117479 1.080114236 1.106513688 0.966342855 1.266633297 1.31986143 1.021920387 1.149731942 1.155318009 1 12.83025244 -6.434417379 1.014129122 0.981185741 1.17213631 0.117869002 0.109807793 0.368934282 0.755484113 0.017678362 0.033438635 3.68E-07 6.434417379 0.190950568 DGVLTLANNVT(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 3 DGVLTLANNVTPAK 14 0 E7EVA0;P27816;P27816-6 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 DGVLTLANNVT(1)PAK;DGVLT(0.029)LANNVT(0.971)PAK;DGVLTLANNVT(1)PAK ;; 189.1 2.19E-05 32458000 7910.4 6793.9 7639.1 7136.5 9362.2 10894.4 9610 4725.66 7546.8 5808 TRUE FALSE FALSE 7284.283493 7381.134443 7922.211766 7106.971054 9250.56188 8634.778635 9879.630736 6166.49198 6718.934921 6009.827568 1.212061979 1.228177408 1.318209495 1.18255823 1.53923915 1.436776436 1.643912512 1.026068038 1.117991298 1 12.55310788 -7.634727806 0.39091385 0.99221593 1.425865616 0.329495551 0.165944174 0.700688953 0.298603836 0.111656326 0.091355889 2.32E-08 7.634727806 0.433649686 DGVLTLANNVT(ph)PAKDVPPLSETEATPVPIK ddPTM_HeLa_Curcumin_4h_R1 1 DGVLTLANNVTPAKDVPPLSETEATPVPIK 30 1 E7EVA0;P27816;P27816-6 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 DGVLT(0.001)LANNVT(0.999)PAKDVPPLSETEATPVPIK 82.942 3.75E-06 15582000 2306.8 1582.7 1859.9 1777.3 2271.5 2696.1 2195.6 938.7 1831.8 1617.3 TRUE FALSE FALSE 2124.214346 1719.501536 1928.82953 1769.946004 2244.413846 2136.898469 2257.202627 1224.905309 1630.856123 1673.501055 1.269323578 1.027487572 1.152571446 1.057630647 1.341148749 1.276902971 1.348790681 0.731941761 0.974517535 1 10.70865374 DGVLTLANNVT(ph)PAKDVPPLSETEATPVPIKDMEIAQTQK ddPTM_HeLa_Curcumin_4h_R1 1 DGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQK 39 2 E7EVA0;P27816;P27816-6 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 DGVLT(0.303)LANNVT(0.694)PAKDVPPLS(0.001)ETEAT(0.001)PVPIKDMEIAQTQK 65.152 1.12E-05 17735000 3433.1 2891 2953.4 2742.1 2967 5073.7 3299.4 1377.4 4251.7 3035 TRUE FALSE FALSE 3161.366512 3140.885158 3062.855602 2730.753917 2931.620463 4021.357428 3391.972284 1797.362919 3785.299147 3140.466024 1.006655219 1.000133462 0.975286973 0.8695378 0.933498545 1.280497033 1.080085649 0.572323631 1.205330393 1 11.61676295 -4.255754728 24.70828172 1.009931104 0.572323408 0.568046113 0.119693886 271.1487328 1178503.285 0.014223778 0.167480014 5.55E-05 4.255754728 -0.437607696 DGVLTLANNVTPAK ddPTM_HeLa_Curcumin_4h_R1 1 DGVLTLANNVTPAK 14 0 E7EVA0;P27816;P27816-6 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 0 0 182.1 5.98E-08 970940 513.43 582.16 375.45 464.33 452.02 608.18 448.56 336.18 460.85 463.83 FALSE FALSE TRUE 472.7914737 632.4793163 389.3645073 462.4087255 446.6299567 482.0366124 461.1453864 438.6797344 410.295908 479.948058 0.985088836 1.317807846 0.811263846 0.963455769 0.930579777 1.004351626 0.960823528 0.914015021 0.85487565 1 8.906734469 DGVVEITGK ddPTM_HeLa_Curcumin_4h_R1 2 DGVVEITGK 9 0 P04792 P04792 HSPB1 Heat shock protein beta-1 0 0 ; ; 138.98 0.00010397 14641200 13371.1 10884.4 13064 12903 14757.8 17397.3 13180.6 10777.5 11408.2 10798.4 FALSE FALSE TRUE 12312.76333 11825.19904 13548.16333 12849.6108 14581.82287 13788.90387 13550.41216 14063.51014 10156.749 11173.6436 1.101947026 1.058311815 1.212510782 1.1499929 1.305019508 1.234056175 1.212712044 1.258632425 0.908991674 1 13.44781209 -6.911117559 0.439800142 1.011065393 1.269988837 0.781275407 0.055672455 0.304789992 0.139757033 0.018437824 0.029764183 1.23E-07 6.911117559 0.258923444 DGVVEITGK(ac)HEER ddPTM_HeLa_Curcumin_4h_R1 2 DGVVEITGKHEER 13 1 P04792 P04792 HSPB1 Heat shock protein beta-1 0 1 ; DGVVEITGK(1)HEER;DGVVEITGK(1)HEER 147.52 0.00039938 15457800 5737.1 4802.4 5101.3 5093.6 6588.4 8683.5 6175.2 6275.5 6623.5 4573.3 FALSE TRUE FALSE 5283.002481 5217.498057 5290.358666 5072.524033 6509.837633 6882.444217 6348.459492 8188.871061 5896.918621 4732.221835 1.116389439 1.102547226 1.117943928 1.071911717 1.375640843 1.454379033 1.341538861 1.730449532 1.246120496 1 12.20830199 -1.000000005 0.295489203 1.021748682 6.600050356 0.750947765 0.105594701 11.83797467 0.151410616 0.031156551 35.20689788 0.099999999 1.000000005 5.578301675 DGVVEITGKHEER ddPTM_HeLa_Curcumin_4h_R1 4 DGVVEITGKHEER 13 1 P04792 P04792 HSPB1 Heat shock protein beta-1 0 0 ;;; ;;; 85.845 0.0037592 28654100 25608.5 19950.3 20945.7 21754.3 18970.2 32785.2 20808.8 18757.1 26582.7 23330.5 FALSE FALSE TRUE 23581.5602 21674.71504 21721.96607 21664.28647 18743.99275 25985.17995 21392.63892 24476.05344 23666.64432 24141.23314 0.976816721 0.897829656 0.899786931 0.897397674 0.776430626 1.076381633 0.886145244 1.01386923 0.980341152 1 14.55921175 -7.390240562 4.397362033 0.990072479 0.918573541 0.133983643 0.075316911 0.30268735 9.298450499 0.012397209 0.014056633 4.07E-08 7.390240562 -0.071498937 DGVY(ph)DVPLHNPPDAK ddPTM_HeLa_Curcumin_4h_R1 1 DGVYDVPLHNPPDAK 15 0 A0A087WUD2;Q14511-3;Q14511 A0A087WUD2 NEDD9 Enhancer of filamentation 1;Enhancer of filamentation 1 p55 1 0 DGVY(1)DVPLHNPPDAK 85.845 0.007337 0 1465.6 1288.9 1529.2 1722 1616 2135.4 1484.1 1049.4 1297.5 1539.1 TRUE FALSE FALSE 1349.596214 1400.306773 1585.873497 1714.87482 1596.730255 1692.493969 1525.739852 1369.357229 1155.167496 1592.58361 0.847425658 0.879267351 0.995786649 1.076787937 1.002603722 1.062734765 0.958028101 0.859833807 0.725341821 1 10.6371534 -6.722455587 15.47405964 0.922287731 0.998527934 0.238004779 0.09133977 4.435250933 1759.103616 0.012826134 0.018133528 1.89E-07 6.722455587 0.076240202 DGWGGYGSDK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 DGWGGYGSDKR 11 1 Q15424-2;Q15424;Q15424-4;Q15424-3;Q14151 Q15424-2;Q14151 SAFB;SAFB2 Scaffold attachment factor B1;Scaffold attachment factor B2 0 1 ; DGWGGYGSDK(1)R;DGWGGYGSDK(1)R 96.015 0.0049023 4829600 2930.1 2753.4 2542.3 2201.06 2743.2 3995.2 2267.44 2582.6 3685 2906.8 FALSE TRUE FALSE 2698.179493 2991.391627 2636.519874 2191.952597 2710.489132 3166.550485 2331.058264 3370.022851 3280.764719 3007.811084 0.897057501 0.994541061 0.87655767 0.728753414 0.901150058 1.052775722 0.775001554 1.120423709 1.090748264 1 11.55449824 -9.327492951 0.78978143 1.006972959 0.910613889 0.134879644 0.115297851 1.658613531 1.630686583 0.104250783 0.020775992 4.70E-10 9.327492951 -0.096359071 DGWQVEEADDWLR ddPTM_HeLa_Curcumin_4h_R1 2 DGWQVEEADDWLR 13 0 E9PK47;P06737-2;P06737 E9PK47 PYGL "Alpha-1,4 glucan phosphorylase;Glycogen phosphorylase, liver form" 0 0 ; ; 221.09 6.42E-13 32556400 4500.4 4322.3 4094.4 4472.5 4790.8 6038.7 4189.3 4190.3 4484.5 4383.6 FALSE FALSE TRUE 4144.188591 4695.900352 4246.142066 4453.99398 4733.672839 4786.20555 4306.840483 5467.90318 3992.56157 4535.929774 0.913635968 1.035267428 0.936112832 0.981936274 1.043594825 1.05517629 0.949494524 1.20546469 0.880207977 1 12.14718259 -1.60139483 1.22909915 0.971888837 199.9999999 0.571196661 0.057525282 690.2379515 1.55068062 0.008069827 386730.0947 0.025038319 1.60139483 199.028111 DGWS(ph)LDR ddPTM_HeLa_Curcumin_4h_R1 1 DGWSLDR 7 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 0 DGWS(1)LDR 99.788 0.019855 7050000 3147.8 3274.6 3079.1 2879.3 3715.8 3422.3 2976.2 1251.3 3083.5 2993.7 TRUE FALSE FALSE 2898.648308 3557.641833 3193.214155 2867.38622 3671.491512 2712.476403 3059.704162 1632.81561 2745.247765 3097.730852 0.935732782 1.148467056 1.030823628 0.92564085 1.185219661 0.875633337 0.98772434 0.527100542 0.886212488 1 11.59699608 -4.260759304 7.200354018 0.991361465 0.520930954 0.674730987 0.097858708 0.044103271 18.80761338 0.012130218 0.099401042 5.49E-05 4.260759304 -0.470430511 DGWS(ph)LDRDR ddPTM_HeLa_Curcumin_4h_R1 2 DGWSLDRDR 9 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 0 DGWS(1)LDRDR;DGWS(1)LDRDR ; 157.97 0.0044712 21375000 8427.4 8223.5 8764.2 8380 8513.8 9003.7 7926.2 3706.1 7869.9 8691.3 TRUE FALSE FALSE 7760.362397 8934.302697 9089.008962 8345.32578 8412.278496 7136.231127 8148.58784 4836.072829 7006.59166 8993.322028 0.86290276 0.993437427 1.010639776 0.927946954 0.935391668 0.793503347 0.906070951 0.537740427 0.779088265 1 13.13463841 -3.846803735 1.177495811 0.940499809 3.84E-26 0.64894612 0.080631242 1.442597956 0.849572339 0.010434057 2.105494741 0.000142297 3.846803735 -0.940499809 DGWSLWYSEYR ddPTM_HeLa_Curcumin_4h_R1 1 DGWSLWYSEYR 11 0 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 0 139.15 0.012563 9359000 499.3 446.37 518.71 527.88 501.17 922.53 652.83 401.15 472.5 576.41 FALSE FALSE TRUE 459.7798781 484.9522338 537.9338489 525.6957724 495.1938751 731.1868789 671.1466528 523.4587883 420.6679321 596.4402046 0.770873383 0.813077707 0.901907425 0.881388894 0.830248986 1.225918161 1.125253877 0.877638335 0.705297746 1 9.220233699 -5.279339554 24.91505261 0.879845458 1.081168513 0.44866801 0.113360629 584.9659325 814206.7852 0.016667792 0.037344431 5.26E-06 5.279339554 0.201323055 DGYDYDGYR ddPTM_HeLa_Curcumin_4h_R1 3 DGYDYDGYR 9 0 J3KTL2;Q07955;Q07955-3;Q07955-2 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 0 ;; ;; 140.14 0.0013979 374957400 6633.1 5623.4 6353 6160.5 5932.1 7377.8 6463 6193.6 6672.9 5585.2 FALSE FALSE TRUE 6108.083136 6109.461639 6588.447769 6135.009483 5861.363582 5847.561115 6644.334386 8082.000128 5940.899565 5779.285284 1.056892476 1.057131001 1.140010822 1.06155159 1.014202154 1.011813888 1.149680983 1.39844284 1.027964406 1 12.49667537 -4.32324987 2.446987451 1.038506468 1.453490141 0.882043771 0.038850764 0.120135521 0.96574655 0.006307617 0.09797857 4.75E-05 4.32324987 0.414983673 DGYGGSRDS(ph)YSSSR ddPTM_HeLa_Curcumin_4h_R1 1 DGYGGSRDSYSSSR 14 1 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 1 0 DGYGGSRDS(0.997)YS(0.002)SSR 139.49 0.0074644 32596000 3772.7 4020.4 3749.5 4088.3 3775 4888.3 4183.6 2057.3 4666.2 3996.1 TRUE FALSE FALSE 3474.086814 4367.905461 3888.459768 4071.383698 3729.985591 3874.411478 4300.980556 2684.561299 4154.329534 4134.964178 0.840173376 1.056334535 0.940385358 0.984623693 0.902059953 0.936987918 1.040149412 0.649234476 1.004683319 1 12.01365912 -4.249133807 24.58414267 0.94208558 0.649234246 0.660950713 0.066157707 856.2974695 1710677.648 0.010212985 0.232911646 5.63E-05 4.249133807 -0.292851334 DGYNYTLSK ddPTM_HeLa_Curcumin_4h_R1 1 DGYNYTLSK 9 0 P31949 P31949 S100A11 "Protein S100-A11;Protein S100-A11, N-terminally processed" 0 0 119.22 0.0078576 0 1531 1003.4 1336 1163.2 1414.1 1672 1423 1353.2 1376.4 1168.2 FALSE FALSE TRUE 1409.819734 1090.129425 1385.513335 1158.386987 1397.237781 1325.208353 1462.92555 1765.784451 1225.412364 1208.794863 1.166301891 0.901831616 1.146193931 0.958299065 1.155893215 1.096305414 1.210234751 1.460780902 1.013747163 1 10.23935372 -3.886310937 1.099292403 1.065998187 1.993472561 0.695589234 0.083231559 1.567370039 0.871142566 0.01299465 2.051654178 0.000129924 3.886310937 0.927474374 DGYQQNFK ddPTM_HeLa_Curcumin_4h_R1 1 DGYQQNFK 8 0 Q14444-2;Q14444;G3V153 Q14444-2 CAPRIN1 Caprin-1 0 0 104.44 0.0047251 0 1080.4 821.03 905.36 995.56 857.75 1154.3 668.26 1078.5 860.4 1034 FALSE FALSE TRUE 994.8852 891.9961748 938.913438 991.4406365 847.5218915 914.8851684 687.0095771 1407.329685 766.0162726 1069.931423 0.929858848 0.833694717 0.877545437 0.926639423 0.792127302 0.855087671 0.642106178 1.315345689 0.715948944 1 10.06330262 -8.017718311 0.961436654 0.98687389 0.878095339 0 0.182783627 0.904773063 1.780002403 0.042163537 0.032758451 9.60E-09 8.017718311 -0.108778551 DHALLEEQSK ddPTM_HeLa_Curcumin_4h_R1 2 DHALLEEQSK 10 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 0 ; ; 128.03 0.00049031 7050100 10996.5 6504.9 8604.4 7971.1 10772.9 13545.8 9437.9 9913.1 7740.3 7653.1 FALSE FALSE TRUE 10126.11542 7067.154571 8923.286633 7938.1177 10644.4402 10736.24839 9702.702073 12935.55856 6891.208455 7919.044655 1.27870417 0.892425144 1.126813526 1.002408503 1.344157113 1.355750454 1.225236439 1.633474632 0.870207046 1 12.95111068 -1 0.483484434 1.106081952 14.86770317 0.563387503 0.150707056 55.45107548 0.554862303 0.029959218 773.7043303 0.1 1 13.76162122 DHANYEEDENGDIT(ph)PIKAK ddPTM_HeLa_Curcumin_4h_R1 1 DHANYEEDENGDITPIKAK 19 1 H3BSB3;H3BNT4;Q99547 H3BSB3 MPHOSPH6 M-phase phosphoprotein 6 1 0 DHANYEEDENGDIT(1)PIKAK 73.735 0.0027129 21420000 3617.4 2792.3 2924.3 3234.3 2902.6 5108.7 3880.6 2457.6 4012.2 3166.4 TRUE FALSE FALSE 3331.078973 3033.65397 3032.67713 3220.917324 2867.988391 4049.098033 3989.479192 3206.910927 3572.071698 3276.432164 1.016678755 0.925901657 0.925603516 0.983056313 0.875338859 1.235825383 1.217629114 0.97878142 1.090232155 1 11.67790995 -5.255911382 24.99993679 0.985855387 1.151433684 0.450524174 0.085325115 296.7189424 1341882.08 0.010955922 0.027098842 5.55E-06 5.255911382 0.165578298 DHAPS(ph)IPT(ph)SPFGDSLESSTELRR ddPTM_HeLa_Curcumin_4h_R1 1 DHAPSIPTSPFGDSLESSTELRR 23 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 2 0 DHAPS(0.994)IPT(0.503)S(0.503)PFGDSLESSTELRR 57.41 0.003172 5379400 1428 1496.6 1254.7 1490.5 1427.2 2011.2 2401 2134.1 1894.4 1644.9 TRUE FALSE FALSE 1314.972293 1625.959435 1301.200286 1484.332706 1410.181572 1594.054449 2468.365598 2784.777266 1686.58906 1702.060153 0.772576863 0.955289055 0.764485488 0.872080052 0.828514533 0.936544133 1.450222305 1.636121533 0.990910372 1 10.73306631 -4.709060758 3.136849663 0.879116765 1.606315669 0.918784674 0.078675132 0.053558629 1.032971916 0.013120132 0.059140353 1.95E-05 4.709060758 0.727198904 DHAPSIPT(ph)SPFGDSLESSTELRR ddPTM_HeLa_Curcumin_4h_R1 1 DHAPSIPTSPFGDSLESSTELRR 23 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 0 DHAPS(0.004)IPT(0.668)S(0.209)PFGDS(0.013)LES(0.033)S(0.037)T(0.037)ELRR 48.286 0.017498 8985000 1154.6 1141.6 1249.8 1158.3 1183.9 1477.7 1236 1171.8 1592.7 1346.1 TRUE FALSE FALSE 1063.212192 1240.274817 1296.118687 1153.507262 1169.782766 1171.208363 1270.678833 1529.076426 1417.984795 1392.876875 0.763321016 0.8904411 0.930533568 0.828147328 0.839832139 0.840855631 0.912269316 1.097782908 1.018025944 1 10.44385202 -4.276344529 3.58840378 0.878800532 1.119608074 0.404322814 0.074715555 0.229361106 5.303909028 0.012300859 0.144703776 5.29E-05 4.276344529 0.240807542 DHAPSIPTS(ph)PFGDSLESSTELRR ddPTM_HeLa_Curcumin_4h_R1 1 DHAPSIPTSPFGDSLESSTELRR 23 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 0 DHAPS(0.005)IPT(0.198)S(0.796)PFGDSLESSTELRR 94.313 6.29E-05 19574000 2217.3 1570.2 1398.2 1549 1723.8 2346.6 1621.6 1656.2 2263.8 1494.3 TRUE FALSE FALSE 2041.798365 1705.921091 1450.018522 1542.590648 1703.244811 1859.888708 1667.097732 2161.167756 2015.466804 1546.226814 1.320503788 1.103279982 0.937778668 0.997648362 1.101549136 1.202856329 1.078171531 1.397704228 1.303474229 1 10.59453625 -4.25538283 23.57268749 1.122933876 1.397704507 0.327055087 0.12081192 335.0256787 1303863.689 0.019562736 0.231269212 5.55E-05 4.25538283 0.274770631 DHFEEAMR ddPTM_HeLa_Curcumin_4h_R1 3 DHFEEAMR 8 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 ;; ;; 145.16 0.0019771 134501600 16462.5 11974.1 13777.2 14053.3 14307.4 17837.3 13890.1 13116 15236.2 13842.8 FALSE FALSE TRUE 15159.47575 13009.08785 14287.79515 13995.15117 14136.7936 14137.64291 14279.81882 17115.00802 13564.82698 14323.83627 1.058339084 0.908212549 0.997483836 0.977053277 0.986941859 0.987001153 0.996926979 1.194862026 0.947010754 1 13.80613031 -4.259410862 24.90242841 1.007794251 1.194862093 0.656702197 0.042735542 88.70988358 1088929.555 0.006138451 0.053987331 5.50E-05 4.259410862 0.187067842 DHFGLEGDEEST(ph)MLEDSVSPK ddPTM_HeLa_Curcumin_4h_R1 1 DHFGLEGDEESTMLEDSVSPK 21 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 0 DHFGLEGDEES(0.146)T(0.782)MLEDS(0.014)VS(0.057)PK 98.165 0.00026238 18857000 2474.4 1714.9 1797.7 1846.5 2084.2 2529 1850.7 1571.2 2588 2073.5 TRUE FALSE FALSE 2278.548629 1863.128315 1864.324343 1838.859672 2059.347276 2004.456892 1902.625661 2050.251647 2304.102875 2145.553971 1.061986163 0.868367023 0.868924468 0.857055892 0.959820776 0.93423746 0.88677595 0.955581484 1.073896488 1 11.06713448 -7.262195439 24.99999681 1.029271245 0.90381168 0.72383951 0.039510897 29.04126991 960276.8112 0.006992294 0.008245253 5.47E-08 7.262195439 -0.125459565 DHFGLEGDEESTMLEDS(ph)VSPK ddPTM_HeLa_Curcumin_4h_R1 3 DHFGLEGDEESTMLEDSVSPK 21 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 0 DHFGLEGDEESTMLEDS(0.779)VS(0.221)PK;DHFGLEGDEESTMLEDS(0.762)VS(0.238)PK;DHFGLEGDEESTMLEDS(0.722)VS(0.278)PK ;; 163.6 7.89E-08 307674000 11275.7 9740 10720.9 9766.1 10867.9 12635.9 10446.9 8829.5 11502.9 11019.3 TRUE FALSE FALSE 10383.21645 10581.8822 11118.22599 9725.690466 10738.30739 10015.0719 10740.0119 11521.5739 10241.06065 11402.21985 0.910631138 0.928054566 0.975093107 0.85296465 0.941773403 0.878344045 0.941922892 1.010467615 0.898163759 1 13.4770271 -9.346106094 0.942317651 1.002414344 0.9266805 0 0.052592495 0.603546163 0.909916351 0.032557285 0.007512734 4.51E-10 9.346106094 -0.075733844 DHFGLEGDEESTMLEDSVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 DHFGLEGDEESTMLEDSVSPK 21 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 0 DHFGLEGDEESTMLEDS(0.362)VS(0.638)PK 120.54 8.39E-06 9999600 1994.4 1253.6 1726.5 1616.3 1765.6 1440.7 1517.7 970.26 1598.5 1255.7 TRUE FALSE FALSE 1836.541136 1361.955598 1790.485609 1609.612179 1744.546373 1141.88258 1560.282577 1266.087807 1423.148549 1299.335482 1.413446459 1.048193956 1.378001012 1.238796448 1.342645066 0.87882044 1.200831194 0.974411786 1.09528953 1 10.34355826 -5.267140206 24.9716307 1.21403725 1.036302147 0.264922094 0.150638256 616.9009403 2702247.439 0.025658352 0.058877487 5.41E-06 5.267140206 -0.177735103 DHFGLEGDEESTMLEDSVS(ph)PKK ddPTM_HeLa_Curcumin_4h_R1 2 DHFGLEGDEESTMLEDSVSPKK 22 1 Q9Y490 Q9Y490 TLN1 Talin-1 1 0 DHFGLEGDEES(0.071)T(0.018)MLEDS(0.417)VS(0.493)PKK;DHFGLEGDEES(0.016)T(0.024)MLEDS(0.299)VS(0.661)PKK ; 60.86 0.002948 68483000 5540 5241.1 5394.1 5393.4 5634.3 6820.9 5445.6 3799.8 6276.3 4859 TRUE FALSE FALSE 5101.503154 5694.11733 5594.010091 5371.08354 5567.114652 5406.168453 5598.38888 4958.341528 5587.805593 5027.849888 1.014649058 1.132515381 1.112604834 1.068266487 1.107255542 1.075244602 1.113475741 0.986175331 1.111370808 1 12.29572586 -7.376402741 6.783480628 1.006466252 1.086946579 0.004968262 0.050556623 0.143800244 7.632746012 0.006115543 0.006969956 4.20E-08 7.376402741 0.080480327 DHFGRTFYNQAIMS(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 DHFGRTFYNQAIMSSK 16 1 A0A0G2JM88;D6R9R1;D6RDF7;Q9HCC0-2;Q9HCC0 A0A0G2JM88 MCCC2 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial" 1 0 DHFGRTFYNQAIMS(0.5)S(0.5)K 64.842 0.014317 15188000 2161.9 1861.3 2093.9 2141.3 2633.2 2355.9 2182.9 2446.8 1442.5 1616.5 TRUE FALSE FALSE 1990.783334 2022.182478 2171.501776 2132.439868 2601.80081 1867.259784 2244.146299 3192.818056 1284.261359 1672.673255 1.190180645 1.208952479 1.298222334 1.274869352 1.555474629 1.11633266 1.341652527 1.908811567 0.767789737 1 10.70793994 -1 0.186267232 0.996693516 3.850769327 0.603846184 0.183956636 28.79990256 0.318617052 0.183827784 23.64731855 0.1 1 2.854075811 ASLSPDASDFEHITAETPS(ph)RPLSST(ph)SNPFK ddPTM_HeLa_Curcumin_4h_R1 1 ASLSPDASDFEHITAETPSRPLSSTSNPFK 30 1 Q5M775-4;Q5M775;Q5M775-5;Q5M775-3;Q5M775-2 Q5M775-4 SPECC1 Cytospin-B 2 0 ASLSPDASDFEHIT(0.078)AET(0.078)PS(0.356)RPLS(0.356)S(0.356)T(0.388)S(0.388)NPFK 52.329 0.012028 7159100 1397.3 1183.8 1274.8 1040.5 1463.5 1287.6 665.72 372.19 2052 1295.4 TRUE FALSE FALSE 1286.702231 1286.122397 1322.045209 1036.194687 1446.048718 1020.537246 684.3983115 485.6690176 1826.900734 1340.415054 0.959928216 0.959495638 0.986295406 0.773040174 1.078806683 0.761359135 0.510586859 0.362327338 1.362936599 1 10.38846408 -4.810041052 2.029533216 0.969789197 0.373280077 0.713144943 0.145786489 0.07319171 0.564227847 0.010176161 0.053793102 1.55E-05 4.810041052 -0.59650912 down DHIKDEWEGLR ddPTM_HeLa_Curcumin_4h_R1 2 DHIKDEWEGLR 11 1 H0YH15;O60306 H0YH15 AQR Intron-binding protein aquarius 0 0 ; ; 83.862 0.011037 9911600 5294.9 4199.3 4400.2 5449.8 4137 5963.6 4115 3102.2 4963.1 5170.8 FALSE FALSE TRUE 4875.803078 4562.26878 4563.275283 5427.250172 4087.668977 4726.682136 4230.455825 4048.046499 4418.660347 5350.484915 0.911282464 0.852683234 0.852871348 1.014347346 0.76398103 0.883411917 0.790667742 0.756575631 0.825842969 1 12.38545393 -1.000000007 0.092061476 1.098307852 0.191888477 0.110082244 0.080228661 73.3906898 0.488107687 0.626891959 8.438641667 0.099999998 1.000000007 -0.906419375 DHQYQFLEDAVR ddPTM_HeLa_Curcumin_4h_R1 2 DHQYQFLEDAVR 12 0 Q13263-2;Q13263;M0R2I3;M0R3C0 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 0 0 ; ; 122.34 0.0026547 13827200 4788.8 3984.4 4738.7 4190.9 4684.6 5459.6 4194.4 3939.9 4122.4 4128.9 FALSE FALSE TRUE 4409.761427 4328.793782 4914.320391 4173.559166 4628.739205 4327.217418 4312.083575 5141.157373 3670.183034 4272.378968 1.032155963 1.013204544 1.150253858 0.976870076 1.083410259 1.012835577 1.009293325 1.203347693 0.859049036 1 12.06082391 -4.258141577 24.6912425 1.025883075 1.203347772 0.379857165 0.070942812 145.9080122 1092376.996 0.006180702 0.059572866 5.52E-05 4.258141577 0.177464697 DHRDNLEFFLAGIGR ddPTM_HeLa_Curcumin_4h_R1 1 DHRDNLEFFLAGIGR 15 1 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 0 92.151 0.0030719 5680700 4020.3 3660.6 3476.7 3687.6 2886.9 5418.7 2990.2 3350.9 4261.3 4041.5 FALSE FALSE TRUE 3702.089013 3977.005953 3605.54956 3672.341688 2852.475603 4294.800539 3074.096964 4372.573984 3793.846051 4181.941824 0.885255981 0.950995045 0.862171142 0.878142701 0.682093564 1.026987156 0.73508841 1.045584604 0.907197233 1 12.02995728 -9.092317284 0.473503228 1.023389166 0.869852399 0.032993999 0.110692079 2.090502005 0.69622471 0.151015672 0.028359758 8.09E-10 9.092317284 -0.153536767 DHRPPCAQEAPR ddPTM_HeLa_Curcumin_4h_R1 1 DHRPPCAQEAPR 12 1 Q13501;E7EMC7;Q13501-2;E9PFW8;E3W990;C9JRJ8 Q13501 SQSTM1 Sequestosome-1 0 0 72.731 0.015506 891150 633.28 550.04 661.54 545.19 774.51 588.6 486.28 375.06 584.63 571.21 FALSE FALSE TRUE 583.1552198 597.5830067 686.0572543 542.9341482 765.2744741 466.5177251 499.923708 489.4140674 520.4975517 591.059505 0.986626921 1.011036963 1.16072451 0.918577814 1.294750305 0.789290623 0.845809439 0.828028419 0.880617852 1 9.207159571 DHS(ph)PPSQGSPGNSAAR ddPTM_HeLa_Curcumin_4h_R1 2 DHSPPSQGSPGNSAAR 16 0 A0A1W2PRA3;A0A2R8Y701;Q18PE1-2;Q18PE1;Q18PE1-3 A0A1W2PRA3 DOK7 Protein Dok-7 1 0 DHS(0.998)PPS(0.002)QGSPGNSAAR;DHS(0.996)PPS(0.004)QGSPGNSAAR ; 66.264 0.014283 13044800 3436.9 3740.9 3335.1 3351.6 3170.5 3843.2 2706.8 3473.6 3484 3639.3 TRUE FALSE FALSE 3164.865738 4064.246727 3458.70174 3337.731967 3132.693858 3046.076998 2782.745523 4532.68465 3101.813917 3765.765404 0.840430935 1.079261794 0.918459163 0.886335608 0.831887683 0.808886553 0.73895881 1.203655609 0.823687507 1 11.87872741 -6.296472467 4.567687139 0.93667542 0.876839462 0.012810473 0.133813948 0.592260686 29.97582043 0.019866602 0.031373937 5.05E-07 6.296472467 -0.059835958 DHS(ph)PT(ph)PSVFNSDEER ddPTM_HeLa_Curcumin_4h_R1 1 DHSPTPSVFNSDEER 15 0 Q6UN15-5;Q6UN15;Q6UN15-3 Q6UN15-5 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 2 0 DHS(0.999)PT(0.981)PS(0.019)VFNSDEER 118.73 0.0014429 26865000 2133.7 1757.3 2261.9 2054.6 2417.4 2676.8 1869 1934 2284.1 2282.8 TRUE FALSE FALSE 1964.815394 1909.193182 2345.728004 2046.09861 2388.574084 2121.601506 1921.43911 2523.667697 2033.539945 2362.12713 0.831799173 0.808251663 0.993057475 0.866210198 1.011196245 0.898174141 0.813435943 1.068387753 0.860893522 1 11.2058709 DHS(ph)PTPS(ph)VFNSDEER ddPTM_HeLa_Curcumin_4h_R1 1 DHSPTPSVFNSDEER 15 0 Q6UN15-5;Q6UN15;Q6UN15-3 Q6UN15-5 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 2 0 DHS(0.998)PT(0.317)PS(0.401)VFNS(0.284)DEER 105.2 0.0058694 22006000 1936.5 1693.7 1496.7 1737.6 1973.3 2500.5 1492.7 1225 1950.5 1800.2 TRUE FALSE FALSE 1783.223982 1840.095881 1552.169019 1730.410272 1949.769686 1981.868114 1534.581145 1598.496861 1736.53503 1862.756816 0.957303694 0.987834732 0.833264442 0.928951249 1.046711879 1.063943557 0.82382259 0.858135022 0.932239257 1 10.86322363 DHS(ph)PTPSVFNS(ph)DEERYR ddPTM_HeLa_Curcumin_4h_R1 2 DHSPTPSVFNSDEERYR 17 1 Q6UN15-5;Q6UN15;Q6UN15-3 Q6UN15-5 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 2 0 DHS(0.985)PT(0.014)PSVFNS(1)DEERYR;DHS(0.57)PT(0.43)PSVFNS(1)DEERYR ; 153.6 0.00013769 119275000 5497.2 4350.7 4221.3 5430.7 4216.6 6016.3 3368.5 2902.6 6358.1 5406 TRUE FALSE FALSE 5062.090819 4726.755122 4377.745091 5408.229202 4166.319799 4768.451562 3463.011044 3787.589378 5660.632337 5593.858098 0.904937296 0.844990173 0.782598524 0.966815587 0.744802554 0.852444141 0.61907381 0.677097866 1.011937064 1 12.44962794 -2.49830085 0.176786127 1.023950427 3.20E-14 0.700523027 0.069940792 13.12006568 0.225980577 0.09813991 3.26319393 0.003174674 2.49830085 -1.023950427 DHS(ph)PTPSVFNSDEER ddPTM_HeLa_Curcumin_4h_R1 2 DHSPTPSVFNSDEER 15 0 Q6UN15-5;Q6UN15;Q6UN15-3 Q6UN15-5 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 0 DHS(0.999)PTPSVFNSDEER;DHS(0.999)PT(0.001)PSVFNSDEER ; 146.1 0.0002832 45859300 2180.6 1838.75 1599.64 1866.85 2169.91 2273.79 1338.46 1383.01 1854.44 1982.91 TRUE FALSE FALSE 2008.003209 1997.683357 1658.924066 1859.125469 2144.03524 1802.180323 1376.013585 1804.683382 1651.012572 2051.815975 0.978646835 0.973617216 0.808515035 0.906087823 1.044945193 0.878334288 0.670632066 0.879554212 0.804659186 1 11.00268563 -3.570876458 0.270618008 1.005528659 0.499980967 0.012620382 0.105770933 9.71570676 0.40342412 0.045990898 1.742457478 0.000268611 3.570876458 -0.505547692 DHS(ph)PTPSVFNSDEERYR ddPTM_HeLa_Curcumin_4h_R1 4 DHSPTPSVFNSDEERYR 17 1 Q6UN15-5;Q6UN15;Q6UN15-3 Q6UN15-5 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 0 DHS(0.589)PT(0.41)PS(0.001)VFNSDEERYR;DHS(0.98)PT(0.018)PS(0.001)VFNSDEERYR;DHS(0.968)PT(0.031)PSVFNSDEERYR;DHS(0.963)PT(0.036)PSVFNSDEERYR ;;; 90.853 0.0014773 180159000 5611.29 4150.7 3877.94 4340.35 3657.78 5565.36 2867.49 2798.34 6215.34 5172.95 TRUE FALSE FALSE 5167.150475 4509.468013 4021.659868 4322.390782 3614.163362 4411.041601 2947.944052 3651.540984 5533.532752 5352.709627 0.965333604 0.842464532 0.751331596 0.807514527 0.675202582 0.824076385 0.550738646 0.682185517 1.033781605 1 12.38605368 -6.615725174 0.577983799 1.002497961 0.649398239 0.788695678 0.067656158 0.236971208 0.16301688 0.016988249 0.034101552 2.42E-07 6.615725174 -0.353099722 DHYEATAMHR ddPTM_HeLa_Curcumin_4h_R1 2 DHYEATAMHR 10 0 B1AJY6;B1AJY5;B1AJY7;O75832-2;O75832 B1AJY6 PSMD10 26S proteasome non-ATPase regulatory subunit 10 0 0 ; ; 74.841 0.013313 4254400 1618.26 1797.49 1748.12 1667.14 2013.35 2793.3 1917.88 1871 1449.04 1345.66 FALSE FALSE TRUE 1490.173013 1952.857026 1812.906865 1660.241816 1989.342116 2213.938093 1971.690551 2441.459287 1290.083937 1392.421585 1.070202466 1.402489768 1.3019813 1.192341339 1.428692386 1.589991219 1.416015503 1.753390865 0.926503834 1 10.44338037 -4.670057579 0.241576644 0.942302427 2.149593422 0.815431094 0.107267716 2.591320948 0.146932883 0.088552827 0.930597543 2.14E-05 4.670057579 1.207290994 DHYQDPVPGIT(ph)PSSSS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 DHYQDPVPGITPSSSSR 17 0 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 2 0 DHYQDPVPGIT(0.81)PS(0.134)S(0.056)S(0.289)S(0.711)R 107.69 0.0019081 0 1730.4 1475.2 1526.8 1550.6 1681 1999.5 1973 996.14 1599.1 1250.8 TRUE FALSE FALSE 1593.437014 1602.709715 1583.384551 1544.184028 1660.955173 1584.781161 2028.35707 1299.8585 1423.682731 1294.265207 1.231151858 1.23831631 1.223384931 1.193097071 1.283319032 1.224464007 1.56718813 1.004321598 1.099993049 1 10.33791755 -9.691849123 0.327612441 0.847603684 1.282832224 0.237346817 0.133379729 3.383284895 0.379374066 0.557235372 0.055281673 2.03E-10 9.691849123 0.43522854 DHYQDPVPGIT(ph)PSSSSR ddPTM_HeLa_Curcumin_4h_R1 1 DHYQDPVPGITPSSSSR 17 0 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 1 0 DHYQDPVPGIT(0.764)PS(0.039)S(0.014)S(0.014)S(0.168)R 97.662 0.0024922 15326000 2072.2 1861.8 2128.8 2197.1 2420.3 3134.2 2029.2 916.05 1772.4 1508.3 TRUE FALSE FALSE 1908.183183 2022.725696 2207.695201 2188.008982 2391.439503 2484.13159 2086.133891 1195.349428 1577.972154 1560.713313 1.222635296 1.296026426 1.414542429 1.401928826 1.532273406 1.591664254 1.336654127 0.765899424 1.011058304 1 10.60798984 -8.077667505 0.757297055 1.029890913 1.36005945 0.26102215 0.212378267 0.553363741 0.694860116 0.077341662 0.052624929 8.36E-09 8.077667505 0.330168537 DHYQDPVPGITPSSSS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 DHYQDPVPGITPSSSSR 17 0 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 1 0 DHYQDPVPGIT(0.049)PS(0.015)S(0.006)S(0.015)S(0.915)R 102.15 0.0008394 14932000 1879.9 1738.8 1824.4 1766.9 2056.7 2760.1 1791.7 911.85 1897.2 1698.9 TRUE FALSE FALSE 1731.103931 1889.094124 1892.013869 1759.589036 2032.175196 2187.624147 1841.97028 1189.868867 1689.081907 1757.936649 0.984736243 1.074608761 1.076269654 1.000939958 1.156000245 1.244427181 1.047802423 0.676855374 0.960832069 1 10.77966737 -7.27064839 23.28767299 0.992792114 1.052159623 0.027747203 0.139093121 774.4892083 1958521.324 0.023340361 0.026901738 5.36E-08 7.27064839 0.05936751 DIAAHIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 DIAAHIKK 8 1 F8VXL2;F8VRV5;P63167 F8VXL2 DYNLL1 "Dynein light chain 1, cytoplasmic" 0 1 DIAAHIK(1)K 68.735 0.019217 4507800 3752.9 5274.1 2995.2 2987.1 5956.6 9474.9 6112.8 5534.9 10066 4238.8 FALSE TRUE FALSE 3455.854005 5729.969703 3106.204747 2974.740172 5885.571435 7509.698936 6284.308716 7222.46553 8961.784984 4386.097984 0.787910808 1.306393456 0.708193195 0.678220182 1.341869574 1.71215941 1.432778916 1.64667218 2.043224984 1 12.09872233 -5.580043537 5.025000494 0.902603302 1.574657396 0.163750002 0.402698876 0.072112985 3.767702667 0.026293077 0.054058654 2.63E-06 5.580043537 0.672054095 DIATIVADK ddPTM_HeLa_Curcumin_4h_R1 1 DIATIVADK 9 0 Q9Y3A5;A0A087X020 Q9Y3A5 SBDS Ribosome maturation protein SBDS 0 0 142.92 1.32E-05 1831300 2211.4 2011.7 2092.4 2066.1 2108.4 2695.8 2121 1702.9 2487.1 1781.8 FALSE FALSE TRUE 2036.365357 2185.582384 2169.946185 2057.551026 2083.258707 2136.660692 2180.509552 2222.106371 2214.271352 1843.717417 1.104488864 1.185421564 1.176940763 1.1159796 1.129922995 1.158887296 1.182670148 1.205231534 1.200981957 1 10.84840184 -8.43761701 0.419456361 0.980375749 1.174984385 0 0.068383274 0.394903696 0.145532106 0.032846083 0.01228897 3.65E-09 8.43761701 0.194608635 DIAWTEDSKR ddPTM_HeLa_Curcumin_4h_R1 2 DIAWTEDSKR 10 1 D6RD66;O75083 D6RD66 WDR1 WD repeat-containing protein 1 0 0 ; ; 147.73 0.0014099 34618000 3135.3 3021.8 3037 3080.3 3405.9 3577.3 2862.9 3184.2 3297.8 2838 FALSE FALSE TRUE 2887.137697 3282.990927 3149.553892 3067.554535 3365.286867 2835.327656 2943.225269 4155.047922 2936.039591 2936.620289 0.983149816 1.117948732 1.07250975 1.044586713 1.145972763 0.965507072 1.002249177 1.41490813 0.999802256 1 11.51994102 -4.260044664 24.9872594 1.018159069 1.41490826 0.782568419 0.059046141 41.62796373 745713.961 0.00880298 0.073967762 5.49E-05 4.260044664 0.396749191 DIDDDLEGEVTEECGK ddPTM_HeLa_Curcumin_4h_R1 2 DIDDDLEGEVTEECGK 16 0 A0A0J9YYL3;A0A0J9YXJ8;A0A0J9YVP6;A0A0J9YXX5;Q9UHX1-4;Q9UHX1-6;Q9UHX1-3;Q9UHX1-5;Q9UHX1-2;Q9UHX1 A0A0J9YYL3 PUF60 Poly(U)-binding-splicing factor PUF60 0 0 ; ; 282.91 9.38E-65 81954000 7693.9 6056.2 6956.2 5914.5 7934.2 8262 6466.5 6676.6 5626.1 5207.5 FALSE FALSE TRUE 7084.919696 6579.670942 7214.002891 5890.027366 7839.589847 6548.368068 6647.932586 8712.264605 5008.930906 5388.460237 1.314831953 1.221066994 1.338787441 1.093081717 1.454884977 1.215257751 1.23373511 1.616837505 0.929566274 1 12.39565736 -12.70213644 0.200644612 3.50E-13 1.36857245 0.533494225 0.133156257 24.48189246 0.398619616 9.798113352 0.133464887 1.99E-13 12.70213644 1.36857245 DIDEVSSLLR ddPTM_HeLa_Curcumin_4h_R1 1 DIDEVSSLLR 10 0 P50990-2;P50990;P50990-3;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 0 0 185.81 0.0016351 17249000 3333.5 2474.2 2985.1 3316.7 3088.4 3212.3 2953.9 2949.9 3154.3 2996.5 FALSE FALSE TRUE 3069.649958 2688.058823 3095.730432 3302.976374 3051.572847 2546.03277 3036.778484 3849.31093 2808.281182 3100.628152 0.990009059 0.866940082 0.99842041 1.065260396 0.984178914 0.821134507 0.979407506 1.241461646 0.905713631 1 11.5983448 -4.261608827 10.30014051 0.978350742 1.241992631 0.574117541 0.071414534 0.038992987 160.4162977 0.009410364 0.072560763 5.48E-05 4.261608827 0.263641888 DIDHETVVEEQIIGENS(ph)PPDYSEYMTGK ddPTM_HeLa_Curcumin_4h_R1 2 DIDHETVVEEQIIGENSPPDYSEYMTGK 28 0 A0A494C032;H0YJU4;H0YJV7;P25490 A0A494C032 YY1 Transcriptional repressor protein YY1 1 0 DIDHETVVEEQIIGENS(0.788)PPDY(0.113)S(0.04)EY(0.021)MT(0.038)GK;DIDHETVVEEQIIGENS(0.641)PPDY(0.182)S(0.054)EY(0.087)MT(0.036)GK ; 94.73 1.32E-07 52975000 2685.6 2246.08 2659.6 2497.2 3419.7 4402.6 2944.2 2530.3 3094.1 2883.6 TRUE FALSE FALSE 2473.031926 2440.221147 2758.167116 2486.867248 3378.922311 3489.451132 3026.806328 3301.776822 2754.684971 2983.804885 0.828818244 0.817821956 0.924379181 0.833455049 1.132420664 1.169463576 1.014411613 1.106565928 0.923212166 1 11.54293748 -5.754065019 24.99814216 0.903914542 1.103747215 0.731689615 0.064163216 93.40638726 316632.9454 0.012006914 0.023632246 1.76E-06 5.754065019 0.199832673 DIDIHEVR ddPTM_HeLa_Curcumin_4h_R1 6 DIDIHEVR 8 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PRZ7;A0A1W2PQ74 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 0 ;;;;; ;;;;; 126.24 0.0050488 387242600 68144.4 62214 60960.1 65952.4 61816.4 69088.6 59932.9 50571.2 73143 61520.2 FALSE FALSE TRUE 62750.69883 67591.50094 63219.33493 65679.50644 61079.2798 54758.84557 61614.45587 65990.12608 65119.39589 63658.02237 0.98574691 1.061790775 0.993108686 1.03175537 0.95949069 0.860203373 0.967897738 1.036634875 1.022956628 1 15.95805472 -5.605538953 7.868820896 1.00112125 0.948631515 0.251691721 0.046192489 0.27628182 22.84700478 0.006580233 0.013196612 2.48E-06 5.605538953 -0.052489735 DIDILNSAGK(ac)MDK ddPTM_HeLa_Curcumin_4h_R1 3 DIDILNSAGKMDK 13 1 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 0 1 ;; DIDILNSAGK(1)MDK;DIDILNSAGK(1)MDK;DIDILNSAGK(1)MDK 185.59 4.75E-09 4152200 1715.5 1477.93 1550.35 1614.45 1727.76 1695.26 1585.16 1177.33 1690.57 1723.41 FALSE TRUE FALSE 1579.716365 1605.675684 1607.807335 1607.769834 1707.15759 1343.643966 1629.635323 1536.292497 1505.118701 1783.298369 0.885839628 0.900396541 0.901591883 0.901570854 0.957303399 0.753459987 0.913832117 0.861489319 0.844008342 1 10.80033239 -13.52287875 0.193175948 1.540492675 0.860091086 0 0.069660406 33.49141374 0.399515659 6.792032447 0.05274804 3.00E-14 13.52287875 -0.680401588 DIDIS(ph)SPEFK ddPTM_HeLa_Curcumin_4h_R1 1 DIDISSPEFK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 DIDIS(0.5)S(0.5)PEFK 93.561 0.01685 8866400 5183.9 4643.3 5267.6 5269.7 5164.6 7067.8 5040.8 4425.7 5427.8 4112.9 TRUE FALSE FALSE 4773.588845 5044.646162 5462.82189 5247.895378 5103.015518 5601.858609 5182.231281 5775.075557 4832.38392 4255.822969 1.121660577 1.185351505 1.283611168 1.233109416 1.19906668 1.316280929 1.217680181 1.356982092 1.135475783 1 12.05522242 -7.550062486 0.396871637 0.988720952 1.301776616 0.627472219 0.060062316 0.262931965 0.115059332 0.029095204 0.025839256 2.82E-08 7.550062486 0.313055664 DIDISS(ph)PEFK ddPTM_HeLa_Curcumin_4h_R1 2 DIDISSPEFK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 DIDIS(0.122)S(0.878)PEFK;DIDIS(0.347)S(0.653)PEFK ; 199.19 1.85E-05 2257080000 27583.6 34752.5 22153.1 28401.4 25892.1 32845.8 24544.4 17655.9 25425.8 21303.3 TRUE FALSE FALSE 25400.32895 37756.35125 22974.11337 28283.88253 25583.35362 26033.21083 25233.04981 23039.10263 22636.65335 22043.58809 1.152277426 1.712804245 1.042212968 1.28308887 1.160580279 1.180987901 1.144688864 1.045161184 1.026904207 1 14.42807145 -8.270716885 1.449738636 1.033228433 1.218075906 0.163015599 0.180589387 0.470689974 1.99857615 0.045291217 0.034357619 5.36E-09 8.270716885 0.184847473 DIDISSPEFK ddPTM_HeLa_Curcumin_4h_R1 3 DIDISSPEFK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ;; ;; 138.08 0.00035191 2899800 5794.2 5532.8 5680 6160.8 6280.4 7734.7 5088.5 5273 6668.4 5493.4 FALSE FALSE TRUE 5335.582956 6011.030578 5890.505797 6135.308242 6205.510332 6130.436032 5231.269615 6880.713426 5936.893204 5684.295241 0.938653383 1.05748036 1.036277242 1.079343697 1.091693881 1.078486562 0.920302235 1.21047784 1.044437868 1 12.47276577 -7.242500676 19.9463372 0.971030793 1.062626622 0.155575424 0.071755838 54.43811685 57333.68444 0.010588542 0.012941278 5.72E-08 7.242500676 0.091595828 DIDNNLITST(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 DIDNNLITSTPR 12 0 Q05D32;H0YMH7;Q05D32-2;H0YNU2;H0YNW9 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 0 DIDNNLIT(0.028)S(0.223)T(0.749)PR 127.78 0.007995 109160000 3363.2 3037.1 3586.7 3716.3 3844.6 5869.4 5582.5 1773.5 3711.2 3642.5 TRUE FALSE FALSE 3096.999171 3299.613391 3719.626257 3700.922935 3798.755656 4652.020278 5739.129925 2314.231986 3304.090645 3769.076604 0.821686449 0.875443441 0.986879984 0.981917675 1.007874356 1.234259944 1.522688586 0.614005028 0.876631332 1 11.8799954 -5.568276805 2.587639797 0.919308538 1.159958126 0.137549467 0.215715531 0.334345695 4.505789506 0.029967352 0.069086977 2.70E-06 5.568276805 0.240649588 DIEDVFYK ddPTM_HeLa_Curcumin_4h_R1 1 DIEDVFYK 8 0 J3KTL2;Q07955;Q07955-3;Q07955-2;J3QQV5;J3KSW7 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 0 129.47 0.0017143 860590 1131.1 782.79 1126.9 1159.7 942.64 878.4 832.74 728.37 983.97 1076 FALSE FALSE TRUE 1041.572241 850.4508796 1168.663905 1154.901469 931.3996337 696.2099384 856.1044432 950.44666 876.0309528 1113.39092 0.935495541 0.763838526 1.049643826 1.037282996 0.836543228 0.625305924 0.768916315 0.85365045 0.786813452 1 10.12074451 -5.551903667 6.241638401 0.96205562 0.747646258 0.343510483 0.105932384 0.098378331 12.02944927 0.013239868 0.027087878 2.81E-06 5.551903667 -0.214409362 DIEIS(ph)TEEEKDTGDLKDSSLLK ddPTM_HeLa_Curcumin_4h_R1 1 DIEISTEEEKDTGDLKDSSLLK 22 2 Q4G0J3-3;Q4G0J3 Q4G0J3-3 LARP7 La-related protein 7 1 0 DIEIS(0.72)T(0.277)EEEKDT(0.003)GDLKDSSLLK 80.477 0.00060534 19796000 1405 1058 950.58 1296.7 1369.2 1380 1076.2 1157.9 1481 1192.5 TRUE FALSE FALSE 1293.792767 1149.448806 985.809331 1291.334599 1352.873184 1093.772444 1106.395276 1510.93838 1318.538005 1233.939286 1.048506018 0.931527846 0.798912347 1.046513887 1.096385535 0.886407019 0.896636721 1.224483568 1.068559872 1 10.2690557 -7.276396265 24.08783867 1.022905618 0.975671392 0.039546239 0.114964971 1500.482455 2416499.315 0.018987317 0.021762727 5.29E-08 7.276396265 -0.047234226 DIELVMSQANVSR ddPTM_HeLa_Curcumin_4h_R1 1 DIELVMSQANVSR 13 0 F8VZJ2;F8W0W4;H0YHX9;Q13765;E9PAV3-2;E9PAV3 F8VZJ2 NACA "Nascent polypeptide-associated complex subunit alpha;Nascent polypeptide-associated complex subunit alpha, muscle-specific form" 0 0 130.56 0.0013406 1159700 311.74 228.66 339.55 260.74 224.11 327.28 239.5 141.74 282.3 284.01 FALSE FALSE TRUE 287.0654501 248.4243515 352.1340217 259.661127 221.4376346 259.3984388 246.2197254 184.9558735 251.3323963 293.8793264 0.976814033 0.845327756 1.198226585 0.883563775 0.75349851 0.882669911 0.837825949 0.629359934 0.855223126 1 8.199080063 -6.003716042 19.60374512 0.992183355 0.791725644 0.414278723 0.110134388 5.944081714 31365.4127 0.013880969 0.024635083 9.91E-07 6.003716042 -0.200457711 DIEVLS(ph)EDT(ph)DYEEDEVTKK ddPTM_HeLa_Curcumin_4h_R1 1 DIEVLSEDTDYEEDEVTKK 19 1 H7C5R6;Q4LE39-2;Q4LE39;H0Y7Y8;Q4LE39-4;Q4LE39-3 H7C5R6 ARID4B AT-rich interactive domain-containing protein 4B 2 0 DIEVLS(0.97)EDT(0.702)DY(0.328)EEDEVTKK 72.207 0.0025422 0 1723.6 1494.7 1509 1414.2 1465.4 2073 1602.2 1477.2 1854.7 1287.2 TRUE FALSE FALSE 1587.175241 1623.895208 1564.924867 1408.348415 1447.926062 1643.036432 1647.15342 1927.59148 1651.24405 1331.930104 1.191635534 1.219204523 1.174930173 1.057374115 1.087088622 1.233575566 1.23666656 1.447216692 1.239737765 1 10.37930266 -1 0.024588615 6.49E-14 2.788365839 0.142046954 0.108833537 1236.085444 2.361567395 93.15635275 191.2263566 0.1 1 2.788365839 DIEVLS(ph)EDTDYEEDEVTK ddPTM_HeLa_Curcumin_4h_R1 1 DIEVLSEDTDYEEDEVTK 18 0 H7C5R6;Q4LE39-2;Q4LE39;H0Y7Y8;Q4LE39-4;Q4LE39-3 H7C5R6 ARID4B AT-rich interactive domain-containing protein 4B 1 0 DIEVLS(0.955)EDT(0.045)DYEEDEVTK 96.55 0.00073869 0 1719.2 1161.9 1067.9 1173.3 1034.4 1324.9 863.79 942.12 1446 806.16 TRUE FALSE FALSE 1583.123506 1262.329459 1107.477313 1168.445195 1022.065456 1050.100805 888.0256226 1229.368051 1287.377418 834.174 1.897833672 1.513268765 1.327633459 1.400721187 1.225242522 1.258851037 1.064556822 1.473754937 1.543296024 1 9.704204536 -5.948732714 1.950146656 1.4374343 1.240413987 0.142476541 0.227992574 0.815738409 6.237085822 0.053976802 0.109198851 1.13E-06 5.948732714 -0.197020313 DIEVLS(ph)EDTDYEEDEVTKK ddPTM_HeLa_Curcumin_4h_R1 3 DIEVLSEDTDYEEDEVTKK 19 1 H7C5R6;Q4LE39-2;Q4LE39;H0Y7Y8;Q4LE39-4;Q4LE39-3 H7C5R6 ARID4B AT-rich interactive domain-containing protein 4B 1 0 DIEVLS(0.999)EDT(0.001)DYEEDEVTKK;DIEVLS(0.923)EDT(0.077)DYEEDEVTKK;DIEVLS(0.986)EDT(0.014)DYEEDEVTKK ;; 110.4 0.00022461 24106400 8833 6858.7 6365.2 6531.9 6697.7 7263.8 5493.5 4432.8 8177.5 5608 TRUE FALSE FALSE 8133.858729 7451.535466 6601.099911 6504.872729 6617.834302 5757.206 5647.632825 5784.340314 7280.448709 5802.877583 1.401694007 1.284110402 1.137556293 1.120973627 1.140440102 0.992129494 0.973246936 0.996805504 1.254627313 1 12.50255278 -5.467000264 1.286338164 1.197868347 0.973007164 0.481083176 0.099703361 0.510969167 1.601755838 0.02429855 0.083526323 3.41E-06 5.467000264 -0.224861183 DIIFAIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 DIIFAIKK 8 1 P11177-3;P11177-2;P11177 P11177-3 PDHB "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial" 0 1 DIIFAIK(1)K 98.299 0.0050459 265110 192.62 187.97 264.87 193.64 290.97 231.87 259.25 257.17 338.24 189.48 FALSE TRUE FALSE 177.3739237 204.2172892 274.6863152 192.838769 287.5003728 183.7775483 266.5238573 335.5799491 301.1359182 196.0644159 0.904671676 1.041582626 1.40100035 0.983548025 1.466356715 0.937332496 1.359368838 1.711580082 1.535902968 1 7.615183912 -1 0.327514788 0.958716112 7.72400725 0.109057199 0.261546438 28.78386203 0.365825782 0.059407807 119.1933295 0.1 1 6.765291137 DIIHDPGR ddPTM_HeLa_Curcumin_4h_R1 5 DIIHDPGR 8 0 E9PKZ0;P62917;G3V1A1;E9PKU4 E9PKZ0 RPL8 60S ribosomal protein L8 0 0 ;;;; ;;;; 96.948 0.013442 206893000 53362.1 48113.7 48348.7 51428.4 49214.3 55541.1 44225.1 43898.4 52389.7 44718.4 FALSE FALSE TRUE 49138.43348 52272.43384 50140.54535 51215.60291 48627.45162 44021.24978 45465.93728 57282.82008 46642.68098 46272.36107 1.061939187 1.129668611 1.083596 1.106829254 1.050896269 0.951350845 0.982572236 1.237948934 1.008003048 1 15.49786309 -8.788247122 0.94650702 1.004400678 1.069453175 0.122324925 0.074620549 0.901475863 1.598976386 0.033327739 0.014704932 1.63E-09 8.788247122 0.065052496 NDSVIVADQTPT(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 4 NDSVIVADQTPTPTR 15 0 B8ZZU6;P15336-5;P15336;E9PEK8;H7C2N6;E9PBF9;P15336-3;P15336-7 B8ZZU6 ATF2 Cyclic AMP-dependent transcription factor ATF-2 1 0 NDSVIVADQT(0.188)PT(0.811)PT(0.001)R;NDSVIVADQT(0.01)PT(0.987)PT(0.004)R;NDSVIVADQT(0.001)PT(0.974)PT(0.025)R;NDSVIVADQT(0.001)PT(0.999)PTR ;;; 217.65 7.20E-14 42299500 8130.4 6124.33 7392.7 7818 7077.5 9378.6 10783.4 12482.8 7977.4 6172.04 TRUE FALSE FALSE 7486.870261 6653.689796 7666.679965 7785.651187 6993.105435 7433.372641 11085.95318 16288.74826 7102.299178 6386.517931 1.172292999 1.04183373 1.200447575 1.219076071 1.094979379 1.16391635 1.735836852 2.550489709 1.112076918 1 12.64081384 -4.361560399 1.701569179 1.097647647 2.891129036 0.9760589 0.069722573 0.093782028 0.306604696 0.012453535 0.255438135 4.35E-05 4.361560399 1.793481389 up DIISDTSGDFRK ddPTM_HeLa_Curcumin_4h_R1 1 DIISDTSGDFRK 12 1 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YNP5;H0YN28;H0YKS4;H0YL33;H0YNA0;H0YN52;P07355-2 P07355;P07355-2 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 0 134.75 0.0027241 11367000 3372.5 2344 3536.9 2993.3 3979.4 4335.6 3719.4 4202.2 3041.4 2457.3 FALSE FALSE TRUE 3105.563066 2546.604915 3667.980625 2980.914518 3931.948254 3436.347688 3823.756354 5483.431435 2707.766029 2542.690992 1.221368651 1.001539284 1.442558548 1.172346355 1.546372826 1.351460991 1.503822669 2.15654653 1.064921391 1 11.31214043 -1 0.359300125 1.085221941 12.80783122 0.791696622 0.150989913 17.66514745 0.219431899 0.041271723 143.3608838 0.1 1 11.72260928 up DIISIAEDEDLR ddPTM_HeLa_Curcumin_4h_R1 4 DIISIAEDEDLR 12 0 P12956;P12956-2;B1AHC9 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 0 ;;; ;;; 277.7 1.06E-57 72674000 7550.9 7115 7565.2 6710.1 8972.2 10897.8 8826.8 8069.8 7193.4 6902 FALSE FALSE TRUE 6953.238297 7729.988896 7845.572967 6682.335384 8865.212375 8637.473436 9074.456252 10530.24487 6404.302017 7141.843986 0.973591458 1.082351968 1.098536034 0.93565967 1.241305802 1.209417827 1.2706041 1.47444342 0.896729476 1 12.8020809 -3.001443687 0.398457459 0.983566954 2.636595542 0.825976613 0.071350021 3.410426891 0.173094598 0.015966506 3.349099823 0.000996681 3.001443687 1.653028588 DIKEES(ph)DEEEEDDEESGR ddPTM_HeLa_Curcumin_4h_R1 1 DIKEESDEEEEDDEESGR 18 1 Q96EV2;A8MTF7;Q96EV2-2;H7BXM6;H7C0H2 Q96EV2 RBM33 RNA-binding protein 33 1 0 DIKEES(1)DEEEEDDEESGR 101 0.0006008 108400000 2487.3 1916.8 2031.8 2202.9 2361 2141 1885 2292 2206.5 1932.4 TRUE FALSE FALSE 2290.42758 2082.479651 2107.100295 2193.784983 2332.846617 1696.932466 1937.888027 2990.820249 1964.45247 1999.550756 1.145471088 1.041473763 1.053786851 1.097138933 1.166685372 0.84865686 0.969161708 1.495746102 0.982446914 1 10.96546019 -4.254416751 24.73128304 1.055948863 1.495746341 0.697869291 0.090123494 332.1103698 1169543.923 0.013031916 0.172761669 5.57E-05 4.254416751 0.439797478 DIKEES(ph)DEEEEDDEESGRLR ddPTM_HeLa_Curcumin_4h_R1 2 DIKEESDEEEEDDEESGRLR 20 2 Q96EV2;A8MTF7;Q96EV2-2;H7BXM6;H7C0H2 Q96EV2 RBM33 RNA-binding protein 33 1 0 DIKEES(1)DEEEEDDEESGRLR;DIKEES(1)DEEEEDDEESGRLR ; 71.685 0.0016851 189637000 7060.6 4886.2 5609 6380.8 4997.4 7255.4 5799.1 4875.1 7547.1 5544.7 TRUE FALSE FALSE 6501.74606 5308.541356 5816.874474 6354.39794 4937.809269 5750.548255 5961.807139 6361.495548 6719.202012 5737.377912 1.133226041 0.925255655 1.013855905 1.107543905 0.860638665 1.002295533 1.039117037 1.108780988 1.171127667 1 12.48617583 -7.269089377 24.92585353 1.062912294 1.007535158 0.164105726 0.083832176 1082.318913 3526494.048 0.014246151 0.016443828 5.38E-08 7.269089377 -0.055377136 DILT(ph)S(ph)NMY(ph)QVRQRTLS(ph)YNK ddPTM_HeLa_Curcumin_4h_R1 1 DILTSNMYQVRQRTLSYNK 19 2 Q6AI14 Q6AI14 SLC9A4 Sodium/hydrogen exchanger 4 4 0 DILT(0.964)S(0.964)NMY(0.961)QVRQRT(0.153)LS(0.518)Y(0.44)NK 47.64 0.014813 4690700 1324.5 1169.8 1319.4 1346.6 1488.8 1569.8 1361.5 1391.4 1309.3 1123 TRUE FALSE FALSE 1219.664427 1270.912299 1368.298125 1341.028126 1471.047032 1244.205785 1399.700026 1815.631455 1165.673066 1162.024166 1.049603324 1.093705567 1.177512623 1.154044954 1.265934974 1.070722813 1.204536073 1.56247306 1.003140123 1 10.18242436 -1 0.316104199 1.018451742 5.108261324 0.706147379 0.08575463 20.29236572 0.259013187 0.029547697 48.44390671 0.1 1 4.089809582 DINAYNCEEPTEK ddPTM_HeLa_Curcumin_4h_R1 1 DINAYNCEEPTEK 13 0 P30041 P30041 PRDX6 Peroxiredoxin-6 0 0 260.81 5.24E-63 3279700 792.98 1000.6 956.72 890.92 1040.7 1329.8 824.64 738.76 1284.2 822.29 FALSE FALSE TRUE 730.2147963 1087.087405 992.1768848 887.2336091 1028.290332 1053.98449 847.777179 964.0045232 1143.326473 850.8645163 0.858203371 1.277626913 1.166080928 1.042743694 1.208524169 1.238721876 0.996371529 1.132970649 1.343723297 1 9.732785619 -7.270555445 24.98054105 0.93304048 1.147752365 0 0.155588576 363.7797481 996855.6171 0.015932772 0.018355202 5.36E-08 7.270555445 0.214711886 DINTFVGT(ph)PVEK ddPTM_HeLa_Curcumin_4h_R1 1 DINTFVGTPVEK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 DINT(0.013)FVGT(0.987)PVEK 115.12 0.011784 19354000 2319.4 2194.1 2629.3 3158.2 3885.7 5939.7 6014.4 1463.9 2887 2159.3 TRUE FALSE FALSE 2135.817043 2383.748227 2726.744171 3145.132205 3839.365565 4707.739266 6183.147877 1910.236371 2570.303323 2234.335514 0.955907038 1.066871207 1.220382594 1.407636492 1.718347822 2.106997466 2.76733187 0.854946072 1.150365872 1 11.12563013 -5.976171664 1.409896847 0.988320542 1.984802093 0.406512765 0.444190939 0.236809231 0.937375601 0.064849734 0.142728614 1.06E-06 5.976171664 0.996481551 DIPGLTDTTVPR ddPTM_HeLa_Curcumin_4h_R1 1 DIPGLTDTTVPR 12 0 P62753;A2A3R5 P62753 RPS6 40S ribosomal protein S6 0 0 194.12 4.13E-14 8948800 3348 2462.2 2712.4 3265.3 2970.5 3450.6 2731.5 2676.6 3294.9 2990.1 FALSE FALSE TRUE 3083.002267 2675.021597 2812.92393 3251.789054 2935.078728 2734.906664 2808.138539 3492.683018 2933.457713 3094.005752 0.996443612 0.864581973 0.90915278 1.050996447 0.948633895 0.883937162 0.907606114 1.128854727 0.948109974 1 11.59526016 -7.468742979 24.99873862 0.998431196 0.951522901 0.005490787 0.077288462 618.2800835 285510.1158 0.012454542 0.014232765 3.40E-08 7.468742979 -0.046908295 DIPYHNR ddPTM_HeLa_Curcumin_4h_R1 1 DIPYHNR 7 0 Q14432;Q13370-2;Q13370 Q14432;Q13370-2 PDE3A;PDE3B "cGMP-inhibited 3,5-cyclic phosphodiesterase A;cGMP-inhibited 3,5-cyclic phosphodiesterase B" 0 0 110.61 0.012648 2547800 2950.5 2556 3084.1 3062.8 3180.7 3243.3 2409.6 2462.2 3124.8 3122.9 FALSE FALSE TRUE 2716.964812 2776.929251 3198.399459 3050.126945 3142.77223 2570.60302 2477.206891 3212.913445 2782.017258 3231.420543 0.840795797 0.859352478 0.989781249 0.943896625 0.972566767 0.795502469 0.76659997 0.994272767 0.86092702 1 11.6579528 -9.485249285 1.219332663 1.000189262 0.888249086 0 0.08725732 0.589002218 1.562791784 0.055130737 0.013376674 3.27E-10 9.485249285 -0.111940176 DIRY(ph)NT(ph)VLHY(ph)AVCGQS(ph)LS(ph)LVEK ddPTM_HeLa_Curcumin_4h_R1 1 DIRYNTVLHYAVCGQSLSLVEK 22 1 C9JIJ7;Q92527;Q92527-2 C9JIJ7 ANKRD7 Ankyrin repeat domain-containing protein 7 5 0 DIRY(1)NT(1)VLHY(1)AVCGQS(1)LS(1)LVEK 45.369 0.0097458 6519700 2287.9 2191.7 2627.7 2310.1 2854.7 2865.4 2370.3 2704.2 2364.1 2282.2 TRUE FALSE FALSE 2106.810301 2381.140782 2725.084874 2300.541418 2820.659567 2271.08374 2436.804239 3528.698131 2104.764145 2361.50628 0.892146813 1.008314397 1.15396046 0.974183909 1.19443238 0.961709803 1.031885564 1.494257356 0.89128035 1 11.20549166 SVGDDEELQQNESGT(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 2 SVGDDEELQQNESGTSPK 18 0 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 1 0 SVGDDEELQQNESGT(0.844)S(0.155)PK;SVGDDEELQQNES(0.145)GT(0.77)S(0.084)PK ; 177.07 2.90E-06 25091000 8082.7 6119 7536.9 7500 6883 6432.4 3676.1 1689.64 8369.6 6567.9 TRUE FALSE FALSE 7442.945766 6647.899094 7816.224144 7468.966987 6800.92472 5098.247732 3779.241472 2204.803458 7451.47582 6796.134036 1.09517348 0.978188343 1.150098586 1.099002307 1.000704913 0.750168803 0.556086954 0.324420243 1.096428614 1 12.73049859 -4.809216795 1.369800208 1.054029603 0.304290015 0.955623158 0.054805449 0.088751521 0.262124969 0.008884457 0.069577219 1.55E-05 4.809216795 -0.749739588 down DISEGGES(ph)PVVQS(ph)DEEEVQVDTALATSHTDR ddPTM_HeLa_Curcumin_4h_R1 1 DISEGGESPVVQSDEEEVQVDTALATSHTDR 31 0 D6RJC6;A0A087WYP9;A6NFV8;Q96EV8-3;Q96EV8 D6RJC6 DTNBP1 Dysbindin 2 0 DIS(0.019)EGGES(0.981)PVVQS(1)DEEEVQVDTALATSHTDR 76.779 4.99E-05 5593600 564.08 479.5 319.81 452.78 364.64 585.2 440.51 410.85 376.23 560 TRUE FALSE FALSE 519.4324728 520.9458434 331.6624399 450.9065163 360.2919062 463.8229234 452.869525 536.1162737 334.9585103 579.4599583 0.89640788 0.899019571 0.572364725 0.778149568 0.621771877 0.80043999 0.78153722 0.925199862 0.578052902 1 9.178565162 -6.979943545 24.61870697 0.948272679 0.7454863 0 0.150129319 123.2609953 151298.6832 0.015468466 0.020328162 1.05E-07 6.979943545 -0.202786379 DISEGGESPVVQS(ph)DEEEVQVDTALATSHTDR ddPTM_HeLa_Curcumin_4h_R1 2 DISEGGESPVVQSDEEEVQVDTALATSHTDR 31 0 D6RJC6;A0A087WYP9;A6NFV8;Q96EV8-3;Q96EV8 D6RJC6 DTNBP1 Dysbindin 1 0 DISEGGES(0.005)PVVQS(0.994)DEEEVQVDTALATSHTDR;DISEGGES(0.004)PVVQS(0.996)DEEEVQVDTALATSHTDR ; 104.32 7.67E-11 21123600 2797.31 2112.55 2831.05 2333.53 2799.49 3132.61 2434.69 1982.97 2702.43 2328.1 TRUE FALSE FALSE 2575.899962 2295.149409 2935.971203 2323.874471 2766.10791 2482.871374 2503.000849 2587.568425 2405.98019 2409.001302 1.069281266 0.952738966 1.21875036 0.96466302 1.148238446 1.03066419 1.039020131 1.074124959 0.998745907 1 11.23421946 -9.55979557 0.511780457 0.979782273 1.064841418 0.105223064 0.074147217 3.597765653 1.07552368 0.159636568 0.016846173 2.76E-10 9.55979557 0.085059145 DISGPS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 DISGPSPSK 9 0 S4R3D6;Q96GX9-3;Q96GX9 S4R3D6 APIP Methylthioribulose-1-phosphate dehydratase 1 0 DIS(0.076)GPS(0.897)PS(0.027)K;DIS(0.023)GPS(0.928)PS(0.049)K ; 126.66 0.0045109 137019000 17347.3 15937.2 18196.9 16957.3 19396.7 19889.4 17513.4 15153.7 15954.2 14233.9 TRUE FALSE FALSE 15974.2429 17314.74055 18871.29312 16887.13519 19165.40702 15764.11424 18004.77887 19773.99337 14204.06418 14728.52697 1.084578447 1.175592141 1.281274982 1.146559681 1.301243978 1.070311666 1.222442605 1.342564224 0.964391362 1 13.84632553 -7.45523825 1.13816217 1.024356959 1.222876038 0.601923276 0.077245649 0.222784435 0.574611433 0.015873447 0.01721912 3.51E-08 7.45523825 0.198519079 DISGPS(ph)PSKK ddPTM_HeLa_Curcumin_4h_R1 1 DISGPSPSKK 10 1 S4R3D6;Q96GX9-3;Q96GX9 S4R3D6 APIP Methylthioribulose-1-phosphate dehydratase 1 0 DIS(0.001)GPS(0.748)PS(0.252)KK 99.5 0.020333 118960000 3300.8 3094.4 3581.6 3493.2 3277.1 3479.2 3045.4 2488.6 3285.6 2655 TRUE FALSE FALSE 3039.538197 3361.866148 3714.337247 3478.746064 3238.022723 2757.574701 3130.845728 3247.362684 2925.1779 2747.261052 1.106388559 1.223715578 1.352014671 1.266259739 1.178636708 1.003754157 1.1396244 1.182036444 1.064761537 1 11.42377829 -7.880116891 1.356773975 1.028621024 1.188466046 0.335850333 0.087295258 0.311784554 1.197277657 0.022580474 0.020334409 1.32E-08 7.880116891 0.159845022 DISLSDYK ddPTM_HeLa_Curcumin_4h_R1 2 DISLSDYK 8 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 0 ; ; 111.95 0.0054204 36370000 19421.8 13889 16995.7 15019.8 16491.3 23531 18759.1 18456.3 15956.4 14345.3 FALSE FALSE TRUE 17884.54404 15089.50327 17625.57559 14957.65205 16294.65202 18650.40535 19285.42986 24083.54091 14206.02284 14843.79811 1.204849588 1.016552715 1.18740335 1.007670135 1.09774142 1.256444288 1.299224748 1.622464866 0.957034227 1 13.85757266 -3.865499522 0.905280679 1.091790945 2.311938129 0.807414398 0.083210765 1.345689776 0.508184495 0.013667093 1.918095565 0.000136301 3.865499522 1.220147185 DISMEIDS(ph)PENMMR ddPTM_HeLa_Curcumin_4h_R1 4 DISMEIDSPENMMR 14 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 0 DIS(0.015)MEIDS(0.985)PENMMR;DISMEIDS(1)PENMMR;DISMEIDS(1)PENMMR;DISMEIDS(1)PENMMR ;;; 121.92 0.0016293 10788200 6328.3 5579.4 5367.01 5998.1 5582.55 7112 5263.97 4261.69 6347.68 5381.75 TRUE FALSE FALSE 5827.408377 6061.658475 5565.916112 5973.281451 5515.981737 5636.891031 5411.662831 5561.059663 5651.355385 5568.765412 1.046445297 1.088510294 0.999488343 1.072640165 0.990521476 1.012233523 0.971788616 0.998616255 1.014830931 1 12.4431418 DISS(ph)SLNSLADSNAR ddPTM_HeLa_Curcumin_4h_R1 1 DISSSLNSLADSNAR 15 0 O94776 O94776 MTA2 Metastasis-associated protein MTA2 1 0 DIS(0.093)S(0.842)S(0.064)LNSLADSNAR 174.18 2.63E-15 0 1343.1 1284.1 1471.6 1158.7 1489.2 1619.2 1193.9 1018 1560.6 1219.8 TRUE FALSE FALSE 1236.792218 1395.091882 1526.138791 1153.905606 1471.442263 1283.359668 1227.397621 1328.383514 1389.406084 1262.187959 0.979879588 1.105296459 1.209121652 0.914210596 1.165786959 1.016773816 0.972436484 1.052445085 1.100791744 1 10.30171105 -7.280121079 24.14951497 0.990498691 1.061020873 0 0.088695828 745.5762588 963791.1987 0.013311794 0.015239519 5.25E-08 7.280121079 0.070522182 DISTNYYASQK ddPTM_HeLa_Curcumin_4h_R1 1 DISTNYYASQK 11 0 P14625;H0YIV0 P14625 HSP90B1 Endoplasmin 0 0 134.38 0.00052569 2294400 2230.5 1544.7 2391.1 1865.1 2231.4 2664.7 2288.5 2180.9 1824.6 2365.2 FALSE FALSE TRUE 2053.953571 1678.216985 2479.716269 1857.38271 2204.792012 2112.011183 2352.709151 2845.84637 1624.445945 2447.390524 0.839242267 0.685716876 1.01320825 0.758923716 0.900874622 0.862964518 0.961313337 1.162808445 0.663746112 1 11.25702861 -4.299145727 2.797735743 0.895284995 1.200228945 0.338824322 0.120621884 0.317389272 3.561216772 0.014569652 0.211123288 5.02E-05 4.299145727 0.30494395 DITDPLSLNTCTDEGHVVLAS(ph)PLK ddPTM_HeLa_Curcumin_4h_R1 2 DITDPLSLNTCTDEGHVVLASPLK 24 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 0 DITDPLS(0.001)LNT(0.011)CT(0.06)DEGHVVLAS(0.928)PLK;DITDPLSLNTCT(0.001)DEGHVVLAS(0.999)PLK ; 117.22 3.53E-07 90346000 5739.4 4800.3 5361.9 5359.7 5751.1 7600.9 4942.9 3073.4 6345 5825.1 TRUE FALSE FALSE 5285.120434 5215.216542 5560.616731 5337.522982 5682.521889 6024.38766 5081.584471 4010.465512 5648.969374 6027.521791 0.87683141 0.865233959 0.922537806 0.88552529 0.942762562 0.99948003 0.843063642 0.66535894 0.93719601 1 12.55734925 -1.000000141 0.02569145 1.536889247 1.21E-07 0.278182643 0.077627925 1708.869076 3.409453689 69.79935471 147.9439848 0.099999968 1.000000141 -1.536889126 DITSDTSGDFR ddPTM_HeLa_Curcumin_4h_R1 4 DITSDTSGDFR 11 0 P04083;Q5T3N1 P04083 ANXA1 Annexin A1;Annexin 0 0 ;;; ;;; 159.79 1.27E-07 345446000 16404.2 13757.4 14439.8 15508.6 14849.2 17676.3 14520.5 14118.2 16334.3 14047.9 FALSE FALSE TRUE 15105.79026 14946.52835 14974.95169 15444.42952 14672.13299 14010.03613 14927.90615 18422.77419 14542.46816 14536.06348 1.039194021 1.028237691 1.030193058 1.062490512 1.009360822 0.963812255 1.026956588 1.267383994 1.000440606 1 13.827349 -4.262636671 6.210767461 1.019169918 1.273165021 0.898080547 0.025227502 0.028814693 5.8783951 0.003694697 0.030812995 5.46E-05 4.262636671 0.253995102 DIWPTRDEIQAVER ddPTM_HeLa_Curcumin_4h_R1 1 DIWPTRDEIQAVER 14 1 P21399 P21399 ACO1 Cytoplasmic aconitate hydratase 0 0 141.73 0.00062421 13803000 2284.7 1701.3 1520.2 2002.5 1934.1 2231.3 1906.5 1598.1 2122.8 1743.2 FALSE FALSE TRUE 2103.863584 1848.352791 1576.539949 1994.214186 1911.037121 1768.503228 1959.991259 2085.353333 1889.934151 1803.77607 1.16636628 1.024713002 0.874021989 1.105577471 1.059464726 0.980444999 1.086604535 1.156104334 1.047765397 1 10.81680453 -4.35011093 3.942259831 1.056419597 1.157876327 0.150014433 0.076175356 0.406740404 10.31896866 0.01240656 0.094542753 4.47E-05 4.35011093 0.10145673 DIYLS(ph)PDR ddPTM_HeLa_Curcumin_4h_R1 1 DIYLSPDR 8 0 Q15696 Q15696 ZRSR2 U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 1 0 DIY(0.001)LS(0.999)PDR 92.239 0.019596 13448000 3399.2 2624.8 3229 3145.5 3882.2 3578.7 2842.1 1583.3 3222.3 2908.7 TRUE FALSE FALSE 3130.149733 2851.676016 3348.669581 3132.484754 3835.907301 2836.43728 2921.841677 2066.040881 2868.821752 3009.777108 1.039993867 0.94747083 1.112597199 1.040769679 1.274482183 0.942407752 0.970783407 0.686443151 0.95316751 1 11.55544094 -4.147046651 1.812815137 1.036775049 0.49780111 0.564668698 0.092986731 0.652070786 1.688782932 0.012386497 0.655589441 7.13E-05 4.147046651 -0.538973939 DK(ac)GEYTLVVK ddPTM_HeLa_Curcumin_4h_R1 2 DKGEYTLVVK 10 1 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 1 ; DK(1)GEYTLVVK;DK(1)GEYTLVVK 152.69 7.07E-08 33344000 3723 5695.6 4240.7 4297.8 7676.7 10951.4 8384.9 7769.8 10466.3 4774.3 FALSE TRUE FALSE 3428.320622 6187.902285 4397.864072 4280.016842 7585.160366 8679.956192 8620.157727 10138.77625 9318.173075 4940.20657 0.69396301 1.252559422 0.89021866 0.866363943 1.53539336 1.757002682 1.744898236 2.052298038 1.886190981 1 12.27035565 -5.598915672 2.285901468 0.884907607 1.849374416 0.410744611 0.355203732 0.080489802 0.84627635 0.026969917 0.063111302 2.52E-06 5.598915672 0.964466809 DK(ac)HIEEVR ddPTM_HeLa_Curcumin_4h_R1 1 DKHIEEVR 8 1 P16949 P16949 STMN1 Stathmin 0 1 DK(1)HIEEVR 70.399 0.010451 0 954.9 1099.7 859.46 989.88 1169.3 1345.5 1075.3 1213.6 1118.5 887.68 FALSE TRUE FALSE 879.3186574 1194.753168 891.3123437 985.7841388 1155.356861 1066.428133 1105.470024 1583.621053 995.8033483 918.5268139 0.957314086 1.300727589 0.97037161 1.073223039 1.257836836 1.161020143 1.203525044 1.724087995 1.084130951 1 9.843178027 -1 0.490023365 1.001613923 20.21850033 0.686540853 0.120554484 33.42750809 0.32916137 0.023164531 662.2401747 0.1 1 19.21688641 DK(ac)KAEGAATEEEGTPK ddPTM_HeLa_Curcumin_4h_R1 1 DKKAEGAATEEEGTPK 16 2 P80723;P80723-2;U3KQP0 P80723 BASP1 Brain acid soluble protein 1 0 1 DK(0.5)K(0.5)AEGAATEEEGTPK 117.53 8.84E-05 1998900 555.84 524.9 424.31 658.7 757.64 1778.7 1154.9 1086.4 1719 586.72 FALSE TRUE FALSE 511.8446775 570.2700171 440.0353019 655.9744739 748.6056378 1409.77757 1187.303386 1417.638359 1530.430001 607.1084763 0.843086034 0.939321455 0.72480507 1.08048973 1.233067346 2.322118081 1.955669262 2.335065996 2.520850985 1 9.245810506 -5.396967899 2.913097718 0.92016071 2.189506068 0.382601506 0.525149694 0.041289968 0.668828277 0.019845784 0.049083779 4.01E-06 5.396967899 1.269345358 DK(ac)LNNLVLFDK ddPTM_HeLa_Curcumin_4h_R1 1 DKLNNLVLFDK 11 1 P62851 P62851 RPS25 40S ribosomal protein S25 0 1 DK(1)LNNLVLFDK 172.13 5.06E-09 805330 134.49 161.35 0 203.94 251.96 280.13 243.71 54.497 276.17 188.53 FALSE TRUE FALSE 123.8449746 175.296375 0 203.0961503 248.9555416 222.0278803 250.5478467 71.11288443 245.8748419 195.0814035 0.634837419 0.898580654 0 1.041084115 1.276162346 1.138129398 1.284324606 0.364529285 1.260370479 1 7.607932446 -6.048585245 24.9999737 0.762227874 1.05807344 0.098717657 0.388156952 588.3303333 302729.7568 0.053654055 0.088976327 8.94E-07 6.048585245 0.295845566 DK(ac)LSGEYEK ddPTM_HeLa_Curcumin_4h_R1 1 DKLSGEYEK 9 1 P34932;A0A087WYC1 P34932 HSPA4 Heat shock 70 kDa protein 4 0 1 DK(1)LSGEYEK 110.39 0.0034335 3502400 1221.7 2073.3 1190.8 1549.4 2772.1 3366.9 2277.6 2462.9 3759.2 1350.5 FALSE TRUE FALSE 1125.001156 2252.506814 1234.932096 1542.988993 2739.044518 2668.566987 2341.503326 3213.826872 3346.825165 1397.429774 0.805050226 1.611892672 0.883716748 1.104162099 1.960058794 1.90962511 1.675578529 2.299812793 2.3949863 1 10.44856007 -5.801232252 4.611972911 0.969584323 1.942364234 0.131456708 0.518167593 0.071154048 3.367323505 0.038020995 0.072261909 1.58E-06 5.801232252 0.972779911 DK(ac)TIIMWK ddPTM_HeLa_Curcumin_4h_R1 1 DKTIIMWK 8 1 P63244;D6RHH4;D6RAC2;D6REE5;D6RAU2;E9PD14;D6RGK8;D6RBD0;D6R909 P63244 GNB2L1 "Guanine nucleotide-binding protein subunit beta-2-like 1;Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed" 0 1 DK(1)TIIMWK 84.213 0.014694 0 71.985 66.023 0 151.59 137.32 260.63 67.293 58.164 0 138.79 FALSE TRUE FALSE 66.28731129 71.72973393 0 150.9627607 135.6825487 206.5724001 69.18106047 75.89793585 0 143.6129422 0.461569203 0.499465667 0 1.051177968 0.944779395 1.438396825 0.481718844 0.528489527 0 1 7.166041958 SPAPGAPTRS(ph)PSTPAK ddPTM_HeLa_Curcumin_4h_R1 1 SPAPGAPTRSPSTPAK 16 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 0 SPAPGAPT(0.022)RS(0.939)PS(0.019)T(0.019)PAK 78.401 0.0059968 45836000 4362.8 3272.5 4484.3 4798.2 3923 4562.9 1718.5 1392.6 4933.3 3626.8 TRUE FALSE FALSE 4017.479776 3555.360318 4650.492103 4778.34632 3876.220787 3616.503106 1766.716485 1817.197329 4392.129333 3752.83103 1.070519761 0.947380868 1.239195707 1.273264445 1.032879113 0.963673311 0.470768993 0.484220396 1.170350942 1 11.87376362 -4.808793301 3.850057206 1.059821049 0.464925624 0.845737742 0.104290884 0.060231362 1.82096537 0.015055613 0.054077457 1.55E-05 4.808793301 -0.594895424 down DKALEEEEDDRPYDPEEEYDPER ddPTM_HeLa_Curcumin_4h_R1 2 DKALEEEEDDRPYDPEEEYDPER 23 2 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 0 0 ; ; 79.695 0.00021706 33282000 7303.1 5990.2 7047.5 6132.1 6954.2 8429.3 6604.6 4668.9 7653.6 6407.6 FALSE FALSE TRUE 6725.051929 6507.966196 7308.68655 6106.726995 6871.275707 6680.968162 6789.907301 6092.426117 6814.019228 6630.263623 1.01429631 0.981554666 1.102322165 0.921038339 1.036350302 1.007647439 1.024078029 0.91888143 1.027714676 1 12.69485052 -4.255257217 24.18932243 1.008753656 0.918881366 0.29456954 0.043189503 394.3081812 1542763.567 0.005084172 0.061878977 5.56E-05 4.255257217 -0.089872289 DKAPVQPQQS(ph)PAAAPGGTDEKPSGK ddPTM_HeLa_Curcumin_4h_R1 4 DKAPVQPQQSPAAAPGGTDEKPSGK 25 2 Q13200;C9JPC0;F8WBS8 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 0 DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK;DKAPVQPQQS(1)PAAAPGGTDEKPSGK ;;; 110.57 5.01E-08 329380000 21571.1 17945.4 19876.3 20217.3 21040.9 22729 20779.3 18692.8 19891.1 18044.1 TRUE FALSE FALSE 19863.72467 19496.52041 20612.93316 20133.64617 20790.00101 18014.74919 21362.31123 24392.14867 17709.0961 18671.13113 1.063873663 1.04420671 1.104000235 1.078330286 1.113483745 0.96484509 1.14413589 1.306409799 0.948474732 1 14.18852171 -4.403919266 3.122865736 1.042947706 1.312676797 0.70330295 0.053222308 0.106431195 1.682884315 0.006627958 0.057131967 3.95E-05 4.403919266 0.269729091 DKAS(ph)PEPEKDFSEK ddPTM_HeLa_Curcumin_4h_R1 1 DKASPEPEKDFSEK 14 2 Q9ULU4-9;Q9ULU4-11;Q9ULU4-23;Q9ULU4-21;Q9ULU4;Q9ULU4-5;H7C4X9;A0A087WYS3;A0A087WVZ6;Q9ULU4-10;Q9ULU4-13;Q9ULU4-20;Q9ULU4-12;Q9ULU4-7;Q9ULU4-19;Q9ULU4-16;Q9ULU4-22;Q9ULU4-18;Q9ULU4-14;Q9ULU4-15;Q9ULU4-6;Q9ULU4-3;Q9ULU4-4;A0A087WV57;Q9ULU4-8;Q9ULU4-17;Q9ULU4-2 Q9ULU4-9 ZMYND8 Protein kinase C-binding protein 1 1 0 DKAS(0.992)PEPEKDFS(0.008)EK 99.011 0.0041437 28498000 3152.4 3058.7 3000 3033.3 3381.7 3469.7 3029.4 2755.5 2800.4 2547.6 TRUE FALSE FALSE 2902.884214 3323.080399 3111.182639 3020.749008 3341.375436 2750.045108 3114.396811 3595.639265 2493.203126 2636.12891 1.101192056 1.260591007 1.180208838 1.145903372 1.267531122 1.04321344 1.181428115 1.363984611 0.945781944 1 11.36420521 -7.899952204 0.828075314 1.016213212 1.200554884 0.514582733 0.085821151 0.337016198 0.500684002 0.024727868 0.019752161 1.26E-08 7.899952204 0.184341672 DKDAYSSFGSR ddPTM_HeLa_Curcumin_4h_R1 2 DKDAYSSFGSR 11 1 A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8Y5G6;A0A2R8YFR4;A0A0D9SFB3;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;A0A0D9SF53;A0A2R8YF78;F6S8Q4;A0A0D9SG12;O15523-2;O15523;A0A2R8YDH3;A0A087WX09;A0A2R8YF89;A0A2R8YCU0;A0A2R8Y650;C9J081;C9J8G5;O15523-3 A0A2R8YCW1 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 0 0 ; ; 102.95 0.0080301 64027000 6369.3 5277.6 5192.3 5876.6 5329.3 6527.8 4966.5 4910.6 6314.3 6106.4 FALSE FALSE TRUE 5865.163184 5733.772227 5384.731206 5852.284186 5265.751578 5173.860697 5105.846623 6407.819334 5621.637088 6318.596945 0.92823822 0.907443896 0.852203622 0.926199952 0.833373552 0.818830627 0.808066517 1.014120601 0.889697054 1 12.62538853 -7.852185929 0.563568418 0.994780415 0.865306434 0.064333183 0.065879421 0.501932241 0.374964562 0.024909593 0.018077979 1.41E-08 7.852185929 -0.129473981 DKDDDEVFEK ddPTM_HeLa_Curcumin_4h_R1 1 DKDDDEVFEK 10 1 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6;C9JF13;C9J6B6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 0 113.61 0.0052196 11076000 6108.6 5492.9 6245 5906.2 7041.3 6199.5 5099.5 4060.2 5202.3 5253.1 FALSE FALSE TRUE 5625.097864 5967.6818 6476.445194 5881.761709 6957.337096 4913.653817 5242.578245 5298.136289 4631.620706 5435.644834 1.034853828 1.097879273 1.191476888 1.082072484 1.279946963 0.903968888 0.964481383 0.974702441 0.852083027 1 12.40823548 DKDDDGGEDDDANCNLICGDEYGPETR ddPTM_HeLa_Curcumin_4h_R1 4 DKDDDGGEDDDANCNLICGDEYGPETR 27 1 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 0 ;;; ;;; 136.37 8.54E-09 327157000 12692.31 10289.79 11159.15 12803.23 11901.16 13616.6 9265.46 8544.14 13288.9 11573.65 FALSE FALSE TRUE 11687.70027 11179.1936 11572.71792 12750.25363 11759.24644 10792.36367 9525.423871 11149.20895 11831.14092 11975.83348 0.975940447 0.933479379 0.966339248 1.06466524 0.981914659 0.901178502 0.795387134 0.930975617 0.987917955 1 13.54783845 -5.160363811 3.697552495 0.987982216 0.86079029 0.582960701 0.043715919 0.114429065 2.860785121 0.005930763 0.016350013 6.91E-06 5.160363811 -0.127191926 DKDDQEWESPS(ph)PPKPTVFISGVIAR ddPTM_HeLa_Curcumin_4h_R1 3 DKDDQEWESPSPPKPTVFISGVIAR 25 2 P51397 P51397 DAP Death-associated protein 1 1 0 DKDDQEWES(0.01)PS(0.988)PPKPT(0.002)VFISGVIAR;DKDDQEWES(0.005)PS(0.995)PPKPTVFISGVIAR;DKDDQEWES(0.055)PS(0.928)PPKPT(0.012)VFIS(0.004)GVIAR ;; 74 0.00020723 1413881700 3794.25 3405.83 3509.92 3228.48 4122.22 3902.56 2827.61 2888.4 3461.14 3209.05 TRUE FALSE FALSE 3493.931109 3700.214769 3640.000723 3215.121405 4073.065219 3093.125065 2906.945126 3769.059863 3081.461601 3320.564249 1.05221006 1.114333135 1.096199456 0.968245504 1.226618404 0.931505863 0.875437097 1.135066086 0.927993368 1 11.6972127 -3.932153446 20.5125464 1.031035554 3.69883365 0.097830737 0.099762899 692.9594262 238619.7551 0.012204149 11659.80281 0.000116909 3.932153446 2.667798096 DKDGNVTQETK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 DKDGNVTQETKK 12 2 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 0 1 ; DKDGNVTQETK(1)K;DKDGNVTQETK(1)K 149.57 1.18E-05 4861200 3804.9 3110.7 3586.4 3501.6 2613.1 3792.5 2285.9 2031.82 3311.9 3616.4 FALSE TRUE FALSE 3503.73815 3379.575047 3719.315139 3487.111307 2581.940489 3005.89275 2350.036202 2651.312565 2948.592856 3742.069631 0.93631025 0.90312992 0.993919276 0.931867028 0.689976602 0.803270128 0.628004402 0.708515027 0.787957774 1 11.86962069 -5.804683852 5.11965643 0.964406525 0.70788224 0.661357494 0.073553189 0.049615287 2.960037492 0.007316479 0.013740504 1.57E-06 5.804683852 -0.256524285 DKDSGSSS(ph)PLPK ddPTM_HeLa_Curcumin_4h_R1 1 DKDSGSSSPLPK 12 1 Q86VQ1;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 0 DKDS(0.096)GS(0.003)S(0.081)S(0.82)PLPK 141.37 0.00043791 0 2729.5 2433.6 3026.8 3086.2 3584 2994.3 2092 1432.9 2810.7 2414 TRUE FALSE FALSE 2513.457195 2643.94954 3138.975871 3073.430122 3541.263141 2373.248427 2150.69589 1869.784614 2502.373242 2497.88632 1.00623362 1.058474727 1.256652813 1.230412328 1.417703885 0.950102656 0.861006312 0.748546721 1.001796287 1 11.28649211 -4.818172374 3.316893286 1.070969387 0.791511502 0.425668422 0.142537152 0.219984443 4.815282907 0.023032158 0.087291564 1.52E-05 4.818172374 -0.279457885 DKEDPQEMPHS(ph)PLGSMPEIR ddPTM_HeLa_Curcumin_4h_R1 1 DKEDPQEMPHSPLGSMPEIR 20 1 G5E9C0;Q9HB58-5;Q9HB58-3;Q9HB58-7;Q9HB58;Q9HB58-6;Q9HB58-2 G5E9C0 SP110 Sp110 nuclear body protein 1 0 DKEDPQEMPHS(0.992)PLGS(0.008)MPEIR 74.408 0.001758 6095000 3741.2 3662.7 3545.9 3758.8 4322.3 4068.7 3428.1 2234.6 3753.7 4069.2 TRUE FALSE FALSE 3445.080072 3979.287467 3677.314173 3743.247082 4270.759395 3224.805756 3524.28326 2915.919253 3341.928501 4210.604397 0.818191344 0.945063248 0.873345921 0.889004696 1.014286547 0.765877164 0.837001753 0.69251798 0.793693301 1 12.03981162 -13.52287875 0.021278401 2.084771913 2.71E-12 0.067254095 0.094211728 2177.968859 3.735720143 246.6111553 135.1472827 3.00E-14 13.52287875 -2.084771913 DKEPFTFS(ph)SPASGR ddPTM_HeLa_Curcumin_4h_R1 1 DKEPFTFSSPASGR 14 1 H0YEX2;Q6P1X5 H0YEX2 TAF2 Transcription initiation factor TFIID subunit 2 1 0 DKEPFT(0.001)FS(0.826)S(0.134)PAS(0.038)GR 107.13 0.0036914 0 1095.1 1051.8 1118.1 974.5 974.24 1244.2 883.82 605.86 899.2 1022 TRUE FALSE FALSE 1008.421679 1142.712905 1159.53777 970.4677772 962.6228243 986.138895 908.6176105 790.583925 800.5600097 1057.514424 0.953577234 1.080564841 1.096474661 0.917687509 0.910269215 0.932506331 0.859201151 0.747586895 0.757020417 1 10.04646163 -3.99257487 0.707475566 0.991222152 0.511946965 0.331150219 0.091213831 1.877418682 0.509131995 0.009804088 0.782690463 0.000101724 3.99257487 -0.479275187 DKEVS(ph)DDEAEEK ddPTM_HeLa_Curcumin_4h_R1 1 DKEVSDDEAEEK 12 1 P07900;P07900-2;G3V2J8 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 0 DKEVS(1)DDEAEEK 137.73 0.014102 59423000 1589.7 1175.2 1483.7 1215.1 1502.2 1080.5 1212.6 1067.4 1090.8 1166 TRUE FALSE FALSE 1463.873568 1276.779051 1538.687227 1210.072238 1484.287246 856.3921203 1246.622292 1392.845346 971.141969 1206.518413 1.213303959 1.058234203 1.275311848 1.002945521 1.230223451 0.709804435 1.033239343 1.154433559 0.80491268 1 10.23663422 DKEVS(ph)DDEAEEKEDKEEEK ddPTM_HeLa_Curcumin_4h_R1 1 DKEVSDDEAEEKEDKEEEK 19 3 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 0 DKEVS(1)DDEAEEKEDKEEEK 106.31 0.0014765 8330900 1647.8 1445.4 1564.1 1529 2014.1 1898.9 1627.7 1689.1 1472.4 2038.9 TRUE FALSE FALSE 1517.374891 1570.333935 1622.066922 1522.673403 1990.083173 1505.046735 1673.368881 2204.098814 1310.881404 2109.751623 0.719219682 0.74432171 0.768842599 0.721731121 0.943278418 0.713376266 0.793159187 1.044719573 0.621343948 1 11.04285745 -9.432842346 1.169372557 0.999721613 0.793659657 0 0.155359721 0.41541847 1.01814598 0.068709221 0.017317875 3.69E-10 9.432842346 -0.206061956 DKGEYTLVVK ddPTM_HeLa_Curcumin_4h_R1 4 DKGEYTLVVK 10 1 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ;;; ;;; 133.89 0.0013393 113099000 27090.6 24992.5 24525.3 24316.4 23471 31074.3 24225.4 21953.6 27202.2 24938.2 FALSE FALSE TRUE 24946.35042 27152.74034 25434.22919 24215.78518 23191.12365 24629.1399 24905.09952 28647.15158 24218.18672 25804.80059 0.966732928 1.052236007 0.985639439 0.938421713 0.898713539 0.954440233 0.965134353 1.110148148 0.938514779 1 14.65535186 -9.594163645 1.233465589 1.000635514 0.978478819 0 0.059469947 2.346974878 6.090227504 0.046240047 0.009470706 2.55E-10 9.594163645 -0.022156695 DKKS(ph)PLIESTANMDNNQSQK ddPTM_HeLa_Curcumin_4h_R1 1 DKKSPLIESTANMDNNQSQK 20 2 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 DKKS(0.839)PLIES(0.06)T(0.101)ANMDNNQSQK 89.659 0.00090158 19980000 4452.7 3650.3 3865.2 4158 3968.8 4099.3 3462.8 7115.2 4502.8 3796.6 TRUE FALSE FALSE 4100.264097 3965.815667 4008.447712 4140.795298 3921.474652 3249.058971 3559.956848 9284.591726 4008.854105 3928.531567 1.043714178 1.009490594 1.020342498 1.054031316 0.998203676 0.827041584 0.906180029 2.363374601 1.020445944 1 11.93977444 -4.258979896 24.99998588 1.002363891 2.363375079 0.974215162 0.067150992 26.05797802 264856.0394 0.010022474 0.090522147 5.51E-05 4.258979896 1.361011188 DKLESEMEDAYHEHQANLLR ddPTM_HeLa_Curcumin_4h_R1 4 DKLESEMEDAYHEHQANLLR 20 1 P23246;P23246-2;H0Y9K7 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 0 ;;; ;;; 88.19 0.00041268 74337200 17857.6 16362.6 17488.8 17860.8 17738.2 21318.2 17020.7 16084.2 20235.5 17595.4 FALSE FALSE TRUE 16444.15212 17776.91023 18136.95031 17786.89674 17526.68355 16896.56501 17498.25503 20988.19854 18015.71628 18206.83884 0.90318546 0.976386422 0.996161413 0.976934925 0.962642868 0.928033975 0.961081448 1.152764559 0.989502705 1 14.15219284 -4.261769027 7.375532269 0.958275127 1.155043071 0.778223209 0.029658848 0.043487195 21.4590212 0.005316686 0.042587828 5.47E-05 4.261769027 0.196767944 DKLGERDDTIPPEYR ddPTM_HeLa_Curcumin_4h_R1 1 DKLGERDDTIPPEYR 15 2 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E7EVY3;E9PCH5;P20810-3;E7EQ12;E7EQA0;H0Y7F0;A0A0A0MR45;H0Y9H6;H0YD33;A0A0C4DGD1 P20810-6 CAST Calpastatin 0 0 58.817 0.018717 10759000 1974 1747.3 1721.6 1780.6 1728.7 1947.5 1359.8 1490.5 2089.3 1846.9 FALSE FALSE TRUE 1817.755817 1898.328826 1785.40401 1773.232349 1708.086382 1543.566547 1397.952328 1944.946589 1860.109017 1911.079638 0.951166964 0.993327954 0.934238414 0.927869417 0.893780849 0.807693472 0.73149873 1.017721371 0.973328887 1 10.90017218 -5.908534854 1.452606231 0.976396626 0.842841633 0.355866093 0.069108389 0.281245517 1.188670154 0.010383871 0.023540017 1.23E-06 5.908534854 -0.133554993 DKLNNLVLFDK ddPTM_HeLa_Curcumin_4h_R1 3 DKLNNLVLFDK 11 1 P62851 P62851 RPS25 40S ribosomal protein S25 0 0 ;; ;; 128.68 0.0016345 27126200 14228.1 10761.9 12344.8 12640 12539 15184.1 13022.4 12097.6 13181.5 12874.1 FALSE FALSE TRUE 13101.93087 11692.11068 12802.30915 12587.69903 12389.48061 12034.7465 13387.7735 15786.10255 11735.52243 13321.47402 0.983519606 0.87768896 0.961027971 0.944917883 0.930038267 0.903409524 1.004976888 1.185011698 0.88094774 1 13.7014661 -4.285355658 3.780567016 0.968704366 1.202211656 0.66879717 0.048713354 0.108122641 2.938402152 0.00648912 0.067240287 5.18E-05 4.285355658 0.23350729 DKLVYNVLY(ph)Y(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 DKLVYNVLYYR 11 1 A0A087WVS4;A0A087WUG7;C9JSN8;A0A087WXZ6;A0A0A0MRM3;Q92637-3;Q92637-2;Q92637;P12314-2;P12314 A0A087WVS4 FCGR1B;FCGR1A High affinity immunoglobulin gamma Fc receptor IB;High affinity immunoglobulin gamma Fc receptor I 2 0 DKLVY(0.049)NVLY(0.951)Y(1)R 76.282 0.011721 15792000 1419.7 1206.9 1315.7 1292.9 1548.8 1663.1 1062.5 1112.2 1312.3 1070.5 TRUE FALSE FALSE 1307.329247 1311.219058 1364.460999 1287.550322 1530.331572 1318.154313 1092.31089 1451.30466 1168.343973 1107.699795 1.180219814 1.183731426 1.231796742 1.162363962 1.381539997 1.189992378 0.986107333 1.310196739 1.054747846 1 10.11335123 -8.928307501 0.609097645 0.986768416 1.205278287 0.33882154 0.097892213 0.752634189 0.484517357 0.086056324 0.022734925 1.18E-09 8.928307501 0.218509871 DKMEGS(ph)DFESSGGR ddPTM_HeLa_Curcumin_4h_R1 1 DKMEGSDFESSGGR 14 1 A0A1B0GW41;Q8WYH8-2;Q8WYH8;E9PEN0 A0A1B0GW41 ING5 Inhibitor of growth protein 5 1 0 DKMEGS(0.673)DFES(0.316)S(0.012)GGR 128.64 0.010858 8403000 2535.9 1919.8 2380.8 2177.5 2524.5 2432.6 2111.2 1782.1 2477.3 1872.1 TRUE FALSE FALSE 2335.180839 2085.738958 2469.034542 2168.490082 2494.396986 1928.051339 2170.43459 2325.454086 2205.546388 1937.155336 1.205469069 1.076701966 1.274567143 1.119419822 1.287659766 0.995300327 1.120423618 1.200447916 1.138549061 1 10.91972393 -9.390472396 1.009982029 0.995929912 1.160973118 0.056573814 0.093754991 0.501192459 0.877702379 0.061714796 0.014302862 4.07E-10 9.390472396 0.165043207 DKNEATVSTGK(ac)IAK ddPTM_HeLa_Curcumin_4h_R1 1 DKNEATVSTGKIAK 14 2 Q9Y450-4;Q9Y450;E9PJ90;E9PN23;G5E991;E9PMN1;E9PLR4;Q9Y450-2 Q9Y450-4 HBS1L HBS1-like protein 0 1 DKNEATVSTGK(1)IAK 113.53 0.000204 1421000 494.82 515.67 609.34 515.61 438.79 624.58 464.05 1047.5 650.96 482.3 FALSE TRUE FALSE 455.6544749 560.242217 631.9226764 513.4765424 433.5577158 495.0350675 477.0699941 1366.877928 579.5513166 499.0598891 0.91302564 1.122595162 1.266226139 1.028887622 0.868748872 0.991935193 0.955937362 2.738905606 1.161286109 1 8.963069145 -4.260756946 24.98897275 0.990264077 2.738906148 0.946643856 0.121001879 8.209961891 300563.8599 0.016286096 0.13053098 5.49E-05 4.260756946 1.74864207 DKPASSMS(ph)DDEMPVLVR ddPTM_HeLa_Curcumin_4h_R1 1 DKPASSMSDDEMPVLVR 17 1 Q05GC8 Q05GC8 BCAR2 1 0 DKPAS(0.015)S(0.047)MS(0.937)DDEMPVLVR 79.283 0.0048377 0 1405.3 995.09 1086.6 1458.2 1366.8 1591.6 1006.7 614.31 1500.5 1099.7 TRUE FALSE FALSE 1294.069022 1081.101146 1126.870352 1452.166355 1350.501803 1261.484219 1034.945293 801.6102911 1335.898904 1137.914493 1.137228702 0.950072393 0.990294401 1.276164741 1.186821867 1.108593156 0.909510599 0.704455647 1.17398883 1 10.15217644 -4.461177091 2.700973861 1.07852774 0.697305278 0.617022922 0.09805996 0.18228051 2.220811727 0.014558544 0.124596105 3.46E-05 4.461177091 -0.381222462 DKPLKDVIIADCGK ddPTM_HeLa_Curcumin_4h_R1 2 DKPLKDVIIADCGK 14 2 P23284 P23284 PPIB Peptidyl-prolyl cis-trans isomerase B 0 0 ; ; 77.192 0.0085 10056200 14008.9 9195.6 13724.3 12288.8 13781.5 15625.2 12842.2 12498.2 12189.1 12040.6 FALSE FALSE TRUE 12900.08078 9990.426689 14232.93463 12237.9522 13617.16461 12384.35739 13202.51757 16308.84365 10851.98623 12459.00995 1.035401756 0.801863609 1.14238087 0.982257198 1.092957198 0.994008146 1.0596763 1.308999969 0.871015134 1 13.60490181 -4.260011177 3.020651099 1.012491824 1.357637285 0.493404994 0.094727065 0.209206433 2.783412965 0.010501063 0.173154818 5.50E-05 4.260011177 0.345145461 DKPTYDEIFYT(ph)LSPVNGK ddPTM_HeLa_Curcumin_4h_R1 2 DKPTYDEIFYTLSPVNGK 18 1 A0A024R571;Q9H4M9 A0A024R571 EHD1 EH domain-containing protein 1 1 0 DKPTYDEIFY(0.007)T(0.496)LS(0.496)PVNGK;DKPTYDEIFY(0.019)T(0.614)LS(0.367)PVNGK ; 78.975 0.0055467 660160000 8624.8 6848.1 7258.6 7398 7685.4 11292.9 8829.8 4955.1 8781.9 6516.8 TRUE FALSE FALSE 7942.137979 7440.019249 7527.610101 7367.389036 7593.756624 8950.625243 9077.540424 6465.88718 7818.547541 6743.258315 1.177789372 1.103327042 1.116316438 1.092556253 1.12612572 1.327344264 1.346165311 0.958866898 1.159461373 1 12.71923015 -13.52287875 0.206620765 0.177782174 1.195754521 0 0.118233568 52.03718112 0.641566123 17.25094929 0.101315049 3.00E-14 13.52287875 1.017972347 DKPVPLPAPEMTVK(ac)QER ddPTM_HeLa_Curcumin_4h_R1 3 DKPVPLPAPEMTVKQER 17 2 Q9H0E9-4;Q9H0E9-2;H7C128;H7C179;H7C127;B5MCW3;Q9H0E9;H0YAH7;Q9H0E9-3 Q9H0E9-4;Q9H0E9-3 BRD8 Bromodomain-containing protein 8 0 1 ;; DKPVPLPAPEMTVK(1)QER;DKPVPLPAPEMTVK(1)QER;DKPVPLPAPEMTVK(1)QER 135.29 7.36E-05 23438400 10209.4 9823.1 10604.9 9775.6 8079 11123.5 11274.4 14419.8 10890.2 10152.8 FALSE TRUE FALSE 9401.315217 10672.16499 10997.92692 9735.151157 7982.663202 8816.360712 11590.72932 18816.33064 9695.572306 10505.60904 0.894885311 1.015854002 1.046862383 0.926662235 0.759847732 0.839205102 1.103289611 1.791074707 0.922894833 1 13.35887218 -4.281681424 3.123125472 0.940001492 1.900615608 0.908338149 0.082123751 0.075232957 1.137719775 0.01257608 0.172165043 5.23E-05 4.281681424 0.960614116 DKPVYDELFYTLS(ph)PINGK ddPTM_HeLa_Curcumin_4h_R1 1 DKPVYDELFYTLSPINGK 18 1 Q9H223 Q9H223 EHD4 EH domain-containing protein 4 1 0 DKPVYDELFYT(0.016)LS(0.984)PINGK 108.28 0.00037236 92788000 3769 2757.9 3238 3059.3 3164.4 5376.6 3944.2 1464 3846.6 2759.7 TRUE FALSE FALSE 3470.679673 2996.280587 3358.003128 3046.641427 3126.666597 4261.432553 4054.863637 1910.366861 3424.637604 2855.59937 1.215394467 1.04926504 1.17593636 1.066900861 1.09492481 1.492307569 1.41996937 0.668989803 1.199271032 1 11.47957787 DKQSPSQANGCS(ph)DHR ddPTM_HeLa_Curcumin_4h_R1 1 DKQSPSQANGCSDHR 15 1 Q9NPI6-2;Q9NPI6;A0A087WT55;A0A087WVE6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 0 DKQSPSQANGCS(1)DHR 70.373 0.012674 6857700 2665.4 2507.2 2186.9 2021.7 2936.4 3995.2 1939.7 1597.5 3203.6 2371.4 TRUE FALSE FALSE 2454.430777 2723.911196 2267.948438 2013.334741 2901.385348 3166.550485 1994.122762 2084.570396 2852.173095 2453.805973 1.000254626 1.110076031 0.924257444 0.820494678 1.182402105 1.290464902 0.812665216 0.849525357 1.162346626 1 11.26080546 KNSTDLDSAPEDPT(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 KNSTDLDSAPEDPTSPK 17 1 I3L2J0;A0A0A0MQR4;Q96RK0;I3L373;I3L135;I3L1Q4 I3L2J0 CIC Protein capicua homolog 1 0 KNSTDLDSAPEDPT(0.967)S(0.033)PK 108.97 0.00057322 0 3516 3276.2 3560.5 3840.1 3321.7 2818.9 1325.8 530.76 3438.2 2332.4 TRUE FALSE FALSE 3237.70489 3559.38013 3692.455262 3824.210684 3282.090897 2234.228364 1362.99838 692.5862807 3061.038062 2413.450726 1.341525167 1.474809529 1.529948477 1.584540609 1.359916265 0.925740203 0.564750863 0.286969306 1.268324242 1 11.23688166 -4.80770219 2.111196539 1.26015187 0.329009544 0.806059432 0.181089164 0.154476765 1.301118217 0.035045486 0.179814396 1.56E-05 4.80770219 -0.931142326 down DKS(ph)DSDTEGLLFSR ddPTM_HeLa_Curcumin_4h_R1 1 DKSDSDTEGLLFSR 14 1 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 DKS(0.563)DS(0.429)DT(0.007)EGLLFSR 118.71 0.018123 38077000 1938 1851.4 2270 2116.7 2300.5 2897.1 2203.2 975.12 1781.4 1771.9 TRUE FALSE FALSE 1784.605255 2011.426766 2354.128197 2107.941656 2273.06804 2296.208803 2265.015862 1272.429599 1585.984877 1833.473393 0.973346688 1.097058061 1.283971835 1.149698525 1.239760581 1.252381852 1.23536882 0.69399949 0.865016576 1 10.84036361 -7.111057598 4.296712504 0.987786293 1.158712212 0.206887073 0.163998241 0.270335776 8.390286924 0.025260242 0.031284446 7.74E-08 7.111057598 0.170925919 DKS(ph)PVREPIDNLTPEER ddPTM_HeLa_Curcumin_4h_R1 4 DKSPVREPIDNLTPEER 17 2 G3XAC6;Q14498-2;Q14498;Q5QP22;Q5QP23;H0Y4X3;Q14498-3 G3XAC6 RBM39 RNA-binding protein 39 1 0 DKS(1)PVREPIDNLTPEER;DKS(0.999)PVREPIDNLT(0.001)PEER;DKS(0.997)PVREPIDNLT(0.003)PEER;DKS(1)PVREPIDNLTPEER ;;; 61.477 0.0093801 3629583000 7049.71 8346.7 6981.3 7712.54 7715.64 9030.5 6941.18 7116.07 9095.9 7821.8 TRUE FALSE FALSE 6491.718015 9068.151556 7240.033119 7680.627553 7623.636032 7157.472505 7135.93083 9285.726985 8098.102527 8093.606968 0.802079721 1.120409181 0.894537275 0.948974615 0.941933067 0.884336555 0.881674988 1.147291563 1.000555446 1 12.98256708 DKWLAPDGLIFPDR ddPTM_HeLa_Curcumin_4h_R1 2 DKWLAPDGLIFPDR 14 1 E9PNR9;E9PQ98;E9PIX6;H0YDE4;E9PKG1;Q99873-2;Q99873-3;Q99873 E9PNR9 PRMT1 Protein arginine N-methyltransferase 1 0 0 ; ; 115.04 0.0019025 54018000 9312.9 8143.4 8581 8439.2 8344.6 10473.6 8561.1 8237.3 9418.7 8810.1 FALSE FALSE TRUE 8575.774138 8847.27921 8899.019409 8404.280826 8245.096095 8301.257298 8801.301425 10748.81485 8385.492174 9116.250319 0.940712885 0.970495423 0.976171024 0.921901059 0.904439414 0.910599973 0.965451926 1.179082899 0.919840053 1 13.15422482 -4.262473602 6.377861198 0.959227101 1.18372429 0.815513916 0.03276066 0.04460274 10.35565276 0.005229574 0.043259269 5.46E-05 4.262473602 0.224497189 DLADELALVDVIEDK ddPTM_HeLa_Curcumin_4h_R1 1 DLADELALVDVIEDK 15 0 P00338;P00338-3;P00338-4;P00338-5;P00338-2;F5GYU2;F5GXY2;F5GXH2;F5GZQ4;F5H5J4;F5H6W8 P00338 LDHA L-lactate dehydrogenase A chain 0 0 193 1.71E-05 134920000 2909.7 2745.6 2851.5 2833.8 3084 3754 3191.2 3040 3067.1 2717.5 FALSE FALSE TRUE 2679.394175 2982.91743 2957.179098 2822.074486 3047.225314 2975.378084 3280.736483 3966.882006 2730.646804 2811.932923 0.952865608 1.060806752 1.051653499 1.003606617 1.083676388 1.058125555 1.166719326 1.410731378 0.97109244 1 11.45734646 -1 0.585872732 0.987809172 24.91424137 0.918654426 0.035925496 28.44905322 0.21244361 0.007069283 870.4970105 0.1 1 23.9264322 DLADELALVDVIEDKLK ddPTM_HeLa_Curcumin_4h_R1 1 DLADELALVDVIEDKLK 17 1 P00338;P00338-3;P00338-4;P00338-5;P00338-2;F5GYU2;F5GXY2;F5GXH2;F5GZQ4;F5H5J4;F5H6W8 P00338 LDHA L-lactate dehydrogenase A chain 0 0 244 1.18E-30 53187000 2391.7 2325.7 2842.6 2280.6 2791.3 4040.2 3026.3 2563.1 2298.4 2675 FALSE FALSE TRUE 2202.394421 2526.723145 2947.949257 2271.163481 2758.015571 3202.216978 3111.209833 3344.577391 2046.27127 2767.956051 0.795675358 0.912848 1.06502748 0.820520066 0.996408729 1.156888664 1.124009838 1.208320266 0.73927159 1 11.43460532 -5.382691935 3.206956573 0.910089035 1.161544671 0.62838873 0.093228935 0.136262202 2.628979205 0.013637874 0.033225911 4.14E-06 5.382691935 0.251455636 DLAEDAPWK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 DLAEDAPWKK 10 1 P21333-2;P21333;F8WE98;Q60FE5;A0A087WWY3;Q14315-2;Q14315;O75369-8;O75369-2;O75369-9;O75369;O75369-6;O75369-3;O75369-5;O75369-4 P21333-2;Q60FE5;Q14315-2;O75369-8 FLNA;FLNC;FLNB Filamin-A;Filamin-C;Filamin-B 0 1 ; DLAEDAPWK(1)K;DLAEDAPWK(1)K 152.97 6.09E-24 6939500 5438.9 7414.9 6024 5618.6 13057.4 14792.8 11277 11089.8 12818.7 5176.7 FALSE TRUE FALSE 5008.405326 8055.810916 6247.254739 5595.351722 12901.69903 11724.60653 11593.40227 14471.02897 11412.52068 5356.58994 0.93499883 1.503906591 1.166274591 1.044573467 2.408565744 2.18881913 2.16432514 2.70153757 2.130557091 1 12.38709914 -5.763576107 24.99230505 1.034258764 2.33877779 0.586518903 0.405016834 12.3542386 144504.4067 0.032202412 0.060513761 1.72E-06 5.763576107 1.304519027 DLAEDAPWKK ddPTM_HeLa_Curcumin_4h_R1 2 DLAEDAPWKK 10 1 P21333-2;P21333;F8WE98;Q60FE5;A0A087WWY3;Q14315-2;Q14315;O75369-8;O75369-2;O75369-9;O75369;O75369-6;O75369-3;O75369-5;O75369-4 P21333-2;Q60FE5;Q14315-2;O75369-8 FLNA;FLNC;FLNB Filamin-A;Filamin-C;Filamin-B 0 0 ; ; 103.88 0.0020663 15019200 13609.2 12466.3 14140 14088.6 15603.1 17075.1 13943.1 12896.6 13055.2 11588.7 FALSE FALSE TRUE 12532.01746 13543.83142 14664.04084 14030.30511 15417.04322 13533.53178 14334.30586 16828.71397 11623.07722 11991.40646 1.045083202 1.129461458 1.222879141 1.170029984 1.285674309 1.128602539 1.195381535 1.403397844 0.9692839 1 13.54971326 -7.012175732 0.888599452 1.010216077 1.242557428 0.684472203 0.070425183 0.220283378 0.346133718 0.014505622 0.019890954 9.72E-08 7.012175732 0.232341351 DLAGSIIGK ddPTM_HeLa_Curcumin_4h_R1 2 DLAGSIIGK 9 0 P61978-3;P61978;P61978-2;S4R359 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 0 ; ; 144.09 1.16E-05 30149000 15062.8 11792.6 11914.8 13165.8 12786.4 15764.2 13268.1 13401.9 15240.8 13289.3 FALSE FALSE TRUE 13870.56349 12811.8998 12356.37297 13111.32341 12633.93053 12494.52722 13640.36718 17488.07762 13568.92237 13751.10219 1.008687398 0.931699847 0.898573278 0.953474364 0.918757665 0.908620055 0.99194719 1.271758247 0.986751621 1 13.74725964 -4.264152865 5.310325856 0.975830528 1.283383317 0.82791529 0.04241693 0.058185098 5.812759075 0.007311528 0.064935308 5.44E-05 4.264152865 0.307552789 DLDAPDDVDFF ddPTM_HeLa_Curcumin_4h_R1 3 DLDAPDDVDFF 11 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;H7C3A1 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 0 ;; ;; 148.04 0.0066541 66898300 21613.4 18209.3 19418.6 19714.8 19285.5 24126.6 18193.9 17325.6 20430.3 18280.6 FALSE FALSE TRUE 19902.67658 19783.23075 20138.2704 19633.22538 19055.53301 19122.4712 18704.37187 22608.09568 18189.1472 18915.84949 1.052169325 1.045854735 1.064624161 1.037924593 1.00738447 1.010923205 0.988820083 1.195193253 0.961582361 1 14.20730795 -9.648617448 0.006642124 1.04E-06 2.035027081 0.197946912 0.054497525 16388.7203 23.19314211 3677.989707 3430.592149 2.25E-10 9.648617448 2.03502604 DLDCS(ph)LEAAAELR ddPTM_HeLa_Curcumin_4h_R1 1 DLDCSLEAAAELR 13 0 Q5T282;Q92966 Q5T282 SNAPC3 snRNA-activating protein complex subunit 3 1 0 DLDCS(1)LEAAAELR 101.45 0.0062966 1825500 1072.4 1114.3 1087.3 1090.8 1034 1450.5 660.9 628.97 1380.3 1064.3 TRUE FALSE FALSE 987.5184084 1210.615127 1127.596294 1086.286559 1021.670225 1149.649949 679.4430753 820.7400576 1228.884543 1101.284346 0.896697036 1.099275706 1.023892057 0.986381549 0.927707934 1.043917453 0.616955174 0.745257172 1.115864897 1 10.1049713 -4.760488139 24.99996959 0.971809434 0.681106111 0.724244497 0.078572546 8.767281376 230379.5949 0.009676673 0.032474937 1.74E-05 4.760488139 -0.290703323 DLDDFQSWLSR ddPTM_HeLa_Curcumin_4h_R1 2 DLDDFQSWLSR 11 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 ; ; 244.16 3.94E-23 191493000 3222.8 2813.5 2885.3 2799 2620.3 4787 3596.1 3128.2 3469.9 2560.23 FALSE FALSE TRUE 2967.711979 3056.686403 2992.231756 2787.41848 2589.054634 3794.122239 3696.996888 4081.97378 3089.260651 2649.197802 1.120230425 1.153815846 1.129485973 1.05217454 0.977297592 1.432177785 1.39551561 1.540833899 1.166111737 1 11.37133985 -5.251192267 24.20072045 1.066114344 1.450109824 0.854538013 0.069729718 119.8562225 283064.4932 0.010170109 0.025588018 5.61E-06 5.251192267 0.38399548 DLDEDELLGNLS(ph)ETELK ddPTM_HeLa_Curcumin_4h_R1 2 DLDEDELLGNLSETELK 17 0 Q9NYL9;H0YNU8 Q9NYL9 TMOD3 Tropomodulin-3 1 0 DLDEDELLGNLS(0.5)ET(0.5)ELK;DLDEDELLGNLS(0.885)ET(0.115)ELK ; 206.62 8.76E-11 7516800 6458.3 5454 7192.2 6192.3 8204.5 8345.3 7324.3 3503.8 5113.5 5684.4 TRUE FALSE FALSE 5947.11874 5925.419457 7458.749259 6166.677903 8106.666696 6614.390709 7529.800146 4572.09249 4552.561843 5881.932477 1.011082457 1.007393315 1.268078015 1.048410183 1.378231853 1.124526801 1.280157529 0.777311285 0.773990837 1 12.52207451 -6.799362908 21.85659149 1.005541283 1.157339574 0.218185525 0.169465306 50.35545444 29021.08621 0.022288467 0.029293829 1.59E-07 6.799362908 0.151798291 DLDEEGS(ph)EK ddPTM_HeLa_Curcumin_4h_R1 1 DLDEEGSEK 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 DLDEEGS(1)EK 94.363 0.016435 16727000 2398.7 2347.2 2531.8 2557.1 2873.8 2960.7 2262.6 2857.3 2980.5 3316.2 TRUE FALSE FALSE 2208.840364 2550.081509 2625.630735 2546.519398 2839.531812 2346.617446 2326.082467 3728.477617 2653.546607 3431.437703 0.643706969 0.7431525 0.765169285 0.742114419 0.827504987 0.683858385 0.677874019 1.086564274 0.773304614 1 11.74459745 -9.491290803 1.23698903 0.999930638 0.751890431 0 0.136418523 0.379553835 1.039715118 0.079349769 0.019351279 3.23E-10 9.491290803 -0.248040206 DLDEEGS(ph)EKELHENVLDK ddPTM_HeLa_Curcumin_4h_R1 1 DLDEEGSEKELHENVLDK 18 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 DLDEEGS(1)EKELHENVLDK 57.484 0.014542 7084800 1108.1 702.56 734.88 863.51 1530.7 943.29 709.42 756.06 783.01 896.73 TRUE FALSE FALSE 1020.392716 763.2861559 762.1152993 859.9370244 1512.447402 747.6410209 729.3244159 986.5792135 697.115762 927.8913008 1.099689926 0.822602987 0.821341141 0.926764831 1.629983384 0.805742031 0.786001998 1.063248694 0.75129033 1 9.857811998 DLDEEIFDDDDFYHQLLR ddPTM_HeLa_Curcumin_4h_R1 2 DLDEEIFDDDDFYHQLLR 18 0 Q9NY61;A0A087WTH8;A0A087WWS8 Q9NY61 AATF Protein AATF 0 0 ; ; 200.81 4.52E-12 58227000 4407.4 4128.6 4096.6 4044.2 4619.7 5504.7 4604.9 3331.5 4388.2 3191.3 FALSE FALSE TRUE 4058.549639 4485.457787 4248.4236 4027.466172 4564.613095 4362.963169 4734.101101 4347.259014 3906.825439 3302.197437 1.229045118 1.358325137 1.286544394 1.219632154 1.382295632 1.321230257 1.433621457 1.316474589 1.183098683 1 11.68921067 -8.829726485 0.296394308 0.88111436 1.384001551 0.54859162 0.078587521 0.784146162 0.119542687 0.142361012 0.036964663 1.48E-09 8.829726485 0.502887191 DLDELSRYPEDK ddPTM_HeLa_Curcumin_4h_R1 2 DLDELSRYPEDK 12 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 0 ; ; 97.163 0.0093879 75701000 13018.3 10828.7 11206.7 10615.8 12499.9 17521.8 13490 10244.9 12007.3 10946.9 FALSE FALSE TRUE 11987.88782 11764.68458 11622.03016 10571.87463 12350.84686 13887.58117 13868.49309 13368.52285 10690.12923 11327.30396 1.058317836 1.03861295 1.026019095 0.933308991 1.090360681 1.22602706 1.224341921 1.180203418 0.943748774 1 13.4675169 -5.416681916 3.967845129 1.022698137 1.210539778 0.823874808 0.042646083 0.066556757 1.836765763 0.005465515 0.01268538 3.83E-06 5.416681916 0.187841641 DLDEMDDDDDDDDVGDHDDDHPGMEVVLHEDK ddPTM_HeLa_Curcumin_4h_R1 6 DLDEMDDDDDDDDVGDHDDDHPGMEVVLHEDK 32 0 Q15029-3;Q15029;K7EIV5;K7EIT3 Q15029-3 EFTUD2 116 kDa U5 small nuclear ribonucleoprotein component 0 0 ;;;;; ;;;;; 114.98 1.57E-13 190532000 31634.6 31897.6 31286.1 30800.5 30495.6 32484.5 27965.7 23133.8 31124.4 36298.2 FALSE FALSE TRUE 29130.68803 34654.68641 32445.59039 30673.05569 30131.95989 25746.84852 28750.34228 30187.18913 27710.13119 37559.55975 0.775586514 0.922659548 0.863843735 0.816651098 0.802244757 0.685493885 0.765460044 0.803715201 0.737765069 1 15.19689253 -13.52287875 0.207431618 1.989901864 0.762655754 0 0.098709087 24.44683936 0.301947389 9.821354363 0.056729731 3.00E-14 13.52287875 -1.22724611 DLDEMDDDDDDDDVGDHDDDHPGMEVVLHEDKK ddPTM_HeLa_Curcumin_4h_R1 5 DLDEMDDDDDDDDVGDHDDDHPGMEVVLHEDKK 33 1 Q15029-3;Q15029;K7EIV5;K7EIT3 Q15029-3 EFTUD2 116 kDa U5 small nuclear ribonucleoprotein component 0 0 ;;;; ;;;; 121.02 5.27E-17 470912000 23861.6 17822 20656.8 21529 20155.5 24131.2 18698.6 17355.9 22431.1 19116.4 FALSE FALSE TRUE 21972.92918 19362.45427 21422.35918 21439.9187 19915.15883 19126.11711 19223.23239 22647.63401 19970.46445 19780.69348 1.11082704 0.978856191 1.082993334 1.083881044 1.006797808 0.96690832 0.97181792 1.144936301 1.009593747 1 14.27180538 -5.734921941 24.933811 1.051956839 1.01500765 0.01505983 0.060343787 494.1873563 464672.3229 0.009224417 0.018443708 1.84E-06 5.734921941 -0.036949189 DLDETLVHS(ph)SFK ddPTM_HeLa_Curcumin_4h_R1 2 DLDETLVHSSFK 12 0 H7C2S4 H7C2S4 CTDSPL 1 0 DLDET(0.201)LVHS(0.4)S(0.4)FK;DLDET(0.287)LVHS(0.356)S(0.356)FK ; 96.034 0.011518 7692000 1254.13 1254.39 1189.42 1183.39 1119.87 1566.82 1221.57 968.47 1237.85 1088.51 TRUE FALSE FALSE 1154.864287 1362.813882 1233.500952 1178.493446 1106.516282 1241.84387 1255.843967 1263.752045 1102.060952 1126.335641 1.025328725 1.209953616 1.095145094 1.046307515 0.982403682 1.102552227 1.114982 1.122003067 0.978448085 1 10.13742109 -7.494370244 23.76643069 1.011174332 1.092739802 0.379006349 0.055423904 167.6913109 139799.984 0.009929349 0.010782764 3.20E-08 7.494370244 0.08156547 DLDIIDNYDYSHTVK ddPTM_HeLa_Curcumin_4h_R1 3 DLDIIDNYDYSHTVK 15 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ;; ;; 128.74 0.00040141 105386900 13281.1 11586.9 12391.1 12213.9 12780.62 14253.3 12379.75 11447.03 11832.3 9805.9 FALSE FALSE TRUE 12229.88692 12588.42001 12850.32507 12163.36212 12628.21945 11297.00491 12727.09247 14937.17675 10534.32629 10146.6543 1.20531227 1.240647374 1.266459337 1.198755941 1.244569795 1.113372407 1.25431419 1.472128282 1.038206879 1 13.30871648 -13.52287875 0.14176801 0.091386323 1.340199281 0.588648135 0.080785908 37.20411684 0.365641097 9.394282765 0.227280791 3.00E-14 13.52287875 1.248812958 DLDLEPLS(ph)DLEEGLEETR ddPTM_HeLa_Curcumin_4h_R1 2 DLDLEPLSDLEEGLEETR 18 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 0 DLDLEPLS(1)DLEEGLEETR;DLDLEPLS(1)DLEEGLEETR ; 182.09 5.64E-07 15397700 1707.43 1334.96 1871.6 1535.06 2235.8 1442.6 1588.64 874.78 1147.61 1368.47 TRUE FALSE FALSE 1572.285114 1450.347994 1940.963142 1528.708328 2209.139545 1143.388499 1633.212963 1141.496395 1021.720054 1416.024231 1.110351843 1.024239531 1.370713227 1.079577803 1.560100101 0.807463936 1.153379248 0.806127727 0.721541364 1 10.46763024 -4.254262191 23.79402403 1.096914155 0.806127459 0.120976432 0.230767569 596.7033056 1978105.506 0.02575749 0.338598932 5.57E-05 4.254262191 -0.290786696 DLDLLASVPS(ph)PSSSGSR ddPTM_HeLa_Curcumin_4h_R1 4 DLDLLASVPSPSSSGSR 17 0 A0A087WV97;Q8WU79-3;Q8WU79-2;Q8WU79 A0A087WV97 SMAP2 Stromal membrane-associated protein 2 1 0 DLDLLAS(0.002)VPS(0.953)PS(0.045)S(0.001)SGSR;DLDLLASVPS(0.945)PS(0.052)S(0.001)SGS(0.001)R;DLDLLASVPS(0.995)PS(0.005)SSGSR;DLDLLASVPS(0.99)PS(0.009)SSGSR ;;; 244.18 1.32E-30 127141000 16427.4 14195.3 15530 14744.2 17460.3 18644.5 14770.8 7692.7 15036.7 12998.5 TRUE FALSE FALSE 15127.15396 15422.27848 16105.55546 14683.19241 17252.09733 14777.42053 15185.22889 10038.16882 13387.21163 13450.19691 1.124678996 1.146621019 1.197421538 1.091671186 1.282665038 1.098676892 1.128996772 0.746321328 0.995317148 1 13.71533967 -4.258386028 24.85044849 1.098323918 0.746321188 0.639872536 0.082518112 149.1904932 1214155.688 0.01261391 0.118916671 5.52E-05 4.258386028 -0.35200273 DLDRPESQS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 DLDRPESQSPK 11 1 Q8WUA4;A0A087WZD8;Q8WUA4-2 Q8WUA4 GTF3C2 General transcription factor 3C polypeptide 2 1 0 DLDRPES(0.037)QS(0.963)PK 72.815 0.015991 336740000 3422.3 3684.1 3790.2 4122.3 4114.8 3583 3030.8 1392.8 4104 3262.4 TRUE FALSE FALSE 3151.421344 4002.537188 3930.668146 4105.243015 4065.733697 2839.845411 3115.836091 1817.458308 3653.801468 3375.768157 0.933541996 1.185667084 1.164377399 1.216091516 1.204387715 0.841244208 0.923000617 0.538383628 1.082361495 1 11.72100011 -4.045339238 1.380482905 1.027693066 0.125232206 0.626537504 0.12292257 1.304205628 1.489908863 0.020689792 1.877925592 9.01E-05 4.045339238 -0.902460859 DLDSLHR ddPTM_HeLa_Curcumin_4h_R1 4 DLDSLHR 7 0 Q8NBS9-2;Q8NBS9 Q8NBS9-2 TXNDC5 Thioredoxin domain-containing protein 5 0 0 ;;; ;;; 147.69 0.0023797 42113300 36256.2 32527.2 31547.5 28706.5 42893.4 57994.5 30700.8 24167.2 45532.8 33763 FALSE FALSE TRUE 33386.48351 35338.70623 32716.6781 28587.72011 42381.92422 45965.78697 31562.18182 31535.66803 40537.96576 34936.26174 0.955639838 1.011519392 0.936467626 0.818282171 1.213121328 1.315704219 0.903421839 0.90266292 1.160340682 1 15.09243762 -5.754474685 24.99942782 0.967673159 1.087418314 0.109861211 0.141219538 236.3950513 848520.6055 0.019024836 0.037401384 1.76E-06 5.754474685 0.119745155 DLEAEHVEVEDTTLNR ddPTM_HeLa_Curcumin_4h_R1 4 DLEAEHVEVEDTTLNR 16 0 H3BV85;H3BTW0;A0A0B4J295;A0A087WZT3;H3BVE0;Q9H3K6-2;Q9H3K6 H3BV85 BOLA2B;BOLA2 BolA-like protein 2 0 0 ;;; ;;; 206.43 1.46E-10 62453000 11295.3 10173.1 10912.3 10640.6 10538.3 12700.2 10486.2 8715.7 11368.7 11024.3 FALSE FALSE TRUE 10401.26509 11052.41743 11316.71944 10596.57202 10412.63766 10066.03536 10780.41455 11373.07681 10121.58205 11407.3936 0.911800315 0.968881921 0.992051281 0.928921398 0.912797263 0.882413258 0.945037484 0.996991706 0.887282617 1 13.47768158 -6.160181833 24.99999898 0.960548645 0.929929204 0.025478256 0.042000606 72.6301535 17917.21896 0.006564411 0.010885844 6.92E-07 6.160181833 -0.030619441 DLEAHIDSANK ddPTM_HeLa_Curcumin_4h_R1 4 DLEAHIDSANK 11 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ;;; ;;; 160.18 0.00027756 57765200 37638.6 34866.2 34869.5 33026.4 46343 52914.9 38190.9 33190.5 37907.3 31012.2 FALSE FALSE TRUE 34659.46509 37879.87897 36161.79434 32889.74551 45790.38999 41939.75327 39262.43387 43310.13066 33748.96403 32089.87164 1.080074906 1.180430991 1.126891212 1.024926054 1.426942136 1.306946744 1.223514831 1.349651103 1.051701434 1 14.9698304 -6.150966775 0.405951791 1.008865284 1.369718354 0.585701102 0.089513142 0.762619253 0.227844405 0.033219242 0.111530613 7.06E-07 6.150966775 0.360853071 DLEALLNSK ddPTM_HeLa_Curcumin_4h_R1 1 DLEALLNSK 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 137.05 0.00021551 938580 891.11 749.54 1147.7 1045.8 1024 1183 1008.8 1034.6 1020.7 890.47 FALSE FALSE TRUE 820.5777032 814.3268977 1190.234772 1041.472757 1011.789469 937.6324648 1037.104213 1350.044777 908.7317637 921.4137662 0.890563755 0.883779826 1.291748415 1.130298672 1.098083734 1.017601971 1.125557541 1.465188417 0.986236365 1 9.847705342 -6.77121624 24.99989022 0.942037167 1.17077174 0.501065876 0.120457556 136.63603 349384.2204 0.019619039 0.025961829 1.69E-07 6.77121624 0.228734573 DLEDGEVPQHAGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 DLEDGEVPQHAGKK 14 1 Q15059;Q15059-2 Q15059 BRD3 Bromodomain-containing protein 3 0 1 ; DLEDGEVPQHAGK(1)K;DLEDGEVPQHAGK(1)K 116.19 8.02E-05 20275300 12776.3 10506.4 11792.1 11534.9 12144.3 15100 9818.6 8563.8 12808.1 12114.9 FALSE TRUE FALSE 11765.04237 11414.5264 12229.1256 11487.17164 11999.48715 11968.08979 10094.08349 11174.8632 11403.08347 12535.89187 0.938508603 0.910547611 0.975528963 0.916342591 0.957210486 0.954705888 0.805214626 0.89142945 0.909634798 1 13.61377702 -1 0.132256001 1.013195021 0.520161497 0.191987978 0.0460702 51.41178066 0.456506149 0.127969103 4.7597779 0.1 1 -0.493033525 DLEDSLAR ddPTM_HeLa_Curcumin_4h_R1 1 DLEDSLAR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 98.458 0.014827 4900000 3249.7 3416.3 3075.6 3512.3 3273 4629.9 3330.7 2837.1 3654.2 3474.6 FALSE FALSE TRUE 2992.482816 3711.589749 3189.584442 3497.767033 3233.971613 3669.60655 3424.150478 3702.11873 3253.343402 3595.342091 0.832322138 1.03233285 0.887143521 0.972860703 0.899489264 1.020655742 0.952385167 1.029698603 0.904877288 1 11.81191333 -4.933245909 0.904231445 0.926669498 1.020364867 0.174235703 0.059890232 1.553169123 1.68525764 0.011740158 0.113720757 1.17E-05 4.933245909 0.093695369 DLEEDHACIPIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 DLEEDHACIPIKK 13 1 P13639 P13639 EEF2 Elongation factor 2 0 1 ; DLEEDHACIPIK(1)K;DLEEDHACIPIK(1)K 116.03 0.00015947 36673000 7762.5 11686.8 7593.8 7192.8 17210.1 19275.3 12801.5 13313 19556.7 7700.5 FALSE TRUE FALSE 7148.089934 12696.95492 7875.232908 7163.038099 17004.8808 15277.3855 13160.67564 17372.07241 17411.37894 7968.091802 0.897089305 1.593474979 0.988346157 0.898965308 2.134122099 1.917320468 1.65167219 2.180204853 2.185137844 1 12.96001855 -5.76459865 24.99999696 1.003578875 1.944210887 0.294576871 0.440981844 26.80951624 212151.9942 0.034651667 0.064779605 1.72E-06 5.76459865 0.940632012 DLEEDHACIPIKK ddPTM_HeLa_Curcumin_4h_R1 3 DLEEDHACIPIKK 13 1 P13639 P13639 EEF2 Elongation factor 2 0 0 ;; ;; 73.632 0.0047807 110397000 26335 20395.1 23341.5 22502.2 25306 20806.1 18156.2 17842.7 24122.6 22455.6 FALSE FALSE TRUE 24250.55696 22157.96157 24206.55652 22409.09186 25004.24248 16490.68033 18665.61411 23282.85709 21476.41113 23235.93043 1.043666275 0.953607674 1.041772637 0.964415517 1.076102485 0.709706047 0.803308228 1.002019573 0.924275927 1 14.50406979 -5.274583428 24.93865436 1.01641315 0.834840971 0.451420176 0.080596131 376.4293968 714212.348 0.010053778 0.022604017 5.31E-06 5.274583428 -0.181572179 DLEGSDIDTR ddPTM_HeLa_Curcumin_4h_R1 4 DLEGSDIDTR 10 0 P55060-4;P55060-3;P55060 P55060-4 CSE1L Exportin-2 0 0 ;;; ;;; 188.66 0.0011632 107290600 12776.8 10247.1 11342 12788.5 11763 12529.8 9849.1 8578.76 13487.3 12328.5 FALSE FALSE TRUE 11765.5028 11132.81366 11762.3445 12735.58458 11622.73391 9930.97824 10125.43924 11194.38443 12007.77693 12756.91446 0.922284369 0.872688588 0.922036793 0.998327975 0.911092878 0.778478077 0.793721654 0.87751505 0.941275962 1 13.6389918 -1 0.104418902 1.056493658 0.340461923 0.405561481 0.054387454 71.25943124 0.526586402 0.39636551 7.358104155 0.1 1 -0.716031735 TGSEPALS(ph)PAVVR ddPTM_HeLa_Curcumin_4h_R1 4 TGSEPALSPAVVR 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 0 TGSEPALS(1)PAVVR;TGSEPALS(1)PAVVR;TGSEPALS(1)PAVVR;T(0.007)GS(0.002)EPALS(0.99)PAVVR ;;; 167.03 0.00018409 723326000 12345 9030.7 9834.8 10654.4 9911.9 8161.1 4307.64 1278.83 10648.5 8122.1 TRUE FALSE FALSE 11367.88022 9811.273468 10199.28634 10610.31492 9793.707066 6468.395865 4428.500785 1668.73938 9480.386191 8404.34237 1.352619839 1.167405257 1.213573399 1.26248009 1.1653151 0.769649258 0.526930078 0.198556806 1.128034268 1 13.03691922 -4.805846148 1.455906525 1.184122242 0.189688561 0.924949124 0.095888769 0.141322951 0.487009687 0.020561269 0.151807321 1.56E-05 4.805846148 -0.99443368 down DLELPLS(ph)PSLLGGPGPER ddPTM_HeLa_Curcumin_4h_R1 2 DLELPLSPSLLGGPGPER 18 0 P19419 P19419 ELK1 ETS domain-containing protein Elk-1 1 0 DLELPLS(0.964)PS(0.036)LLGGPGPER;DLELPLS(0.962)PS(0.038)LLGGPGPER ; 134.4 0.00026723 8125000 4922.9 3870.9 4141.2 4257.9 3883.3 4269.6 3208.4 5409.6 4031.9 4204.6 TRUE FALSE FALSE 4533.24727 4205.483348 4294.676515 4240.281938 3836.994184 3384.036832 3298.419069 7058.962137 3589.610657 4350.709537 1.041955854 0.966620114 0.987120946 0.974618485 0.881923776 0.777812631 0.758133597 1.62248527 0.825063275 1 12.08703499 -7.246676563 21.01235608 1.019812484 0.972528988 0 0.235285921 570.9752694 812680.6471 0.03540276 0.043199512 5.67E-08 7.246676563 -0.047283495 DLENGSHIR ddPTM_HeLa_Curcumin_4h_R1 1 DLENGSHIR 9 0 P25205;P25205-2;J3KQ69;A0A499FHX9 P25205 MCM3 DNA replication licensing factor MCM3 0 0 93.096 0.0048849 1265100 717.19 619.58 715.07 601.66 684.52 850.02 526.88 605.21 884.34 742.96 FALSE FALSE TRUE 660.4236547 673.1337344 741.5711232 599.1704903 676.3575461 673.7162703 541.6628348 789.735743 787.3301145 768.7778047 0.85905661 0.875589449 0.964610475 0.779380579 0.879782873 0.876347192 0.704576578 1.027261373 1.024132213 1 9.586422875 -9.646386509 0.451241828 1.057197316 0.858640114 0.306625905 0.083994524 2.479639361 0.533319623 0.236890246 0.021831258 2.26E-10 9.646386509 -0.198557202 DLESAEERR ddPTM_HeLa_Curcumin_4h_R1 1 DLESAEERR 9 1 O43242 O43242 PSMD3 26S proteasome non-ATPase regulatory subunit 3 0 0 138.4 0.003809 6456000 1791.4 1807.8 1901.3 1995.5 1580.2 2444.5 1777.5 1606.3 2057.9 1736 FALSE FALSE TRUE 1649.6088 1964.058177 1971.763851 1987.24315 1561.357147 1937.483145 1827.371866 2096.053476 1832.153519 1796.325871 0.9183238 1.09337521 1.097664896 1.106282096 0.869194823 1.078581106 1.017283053 1.166855919 1.01994496 1 10.81083338 -7.259321383 24.99861552 0.961430683 1.056027588 0.173296633 0.078500285 201.590905 2379371.974 0.013019399 0.015525424 5.50E-08 7.259321383 0.094596905 DLESCS(ph)DDDNQGSK ddPTM_HeLa_Curcumin_4h_R1 3 DLESCSDDDNQGSK 14 0 F8W895;A0A0A0MRK1;Q5T3I0;E9PAV9;Q5T3I0-3 F8W895 GPATCH4 G patch domain-containing protein 4 1 0 DLES(0.001)CS(0.999)DDDNQGSK;DLES(0.007)CS(0.993)DDDNQGSK;DLES(0.001)CS(0.999)DDDNQGSK ;; 199.15 1.02E-06 71540200 8516.8 8357.4 9736.8 9283.5 10867.3 10911 7085.69 2806.76 8002.2 7304.1 TRUE FALSE FALSE 7842.686293 9079.776416 10097.65437 9245.087337 10737.71455 8647.935608 7284.495391 3662.528203 7124.378681 7557.916931 1.037678287 1.201359647 1.336036697 1.223232198 1.420724076 1.144222103 0.963823162 0.484594927 0.942637865 1 12.88377295 -4.290567165 2.842393087 1.103601377 0.395323435 0.639523721 0.148998927 0.227910118 2.647590199 0.024224281 0.359187138 5.12E-05 4.290567165 -0.708277943 S(ph)LEEDLETLK ddPTM_HeLa_Curcumin_4h_R1 2 SLEEDLETLK 10 0 P48681 P48681 NES Nestin 1 0 S(1)LEEDLETLK;S(1)LEEDLETLK ; 229.68 5.32E-16 25288100 3392.8 3206.6 3559.9 3240.2 3996.8 4517.5 6707 7871.6 2919.39 2727.89 TRUE FALSE FALSE 3124.2563 3483.764216 3691.833026 3226.792911 3949.14077 3580.519577 6895.180369 10271.6146 2599.140221 2822.683974 1.106838856 1.234202712 1.30791582 1.143164782 1.399072941 1.268480499 2.442774477 3.638953102 0.920804541 1 11.4628519 -4.356983358 1.349808973 1.101136168 4.489991484 0.967942622 0.144143355 0.123585535 0.221431423 0.020931207 0.542196813 4.40E-05 4.356983358 3.388855315 up NNS(ph)NTCNIENELEDSRK ddPTM_HeLa_Curcumin_4h_R1 2 NNSNTCNIENELEDSRK 17 1 Q6PL18;A0A0B4J211 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 0 NNS(0.939)NT(0.061)CNIENELEDSRK;NNS(0.999)NT(0.001)CNIENELEDSRK ; 147.17 0.00012154 54531000 2588.81 2119.78 1989.81 2207.32 1933.67 1894.61 1025.14 470.42 2108.71 1853.02 TRUE FALSE FALSE 2383.902957 2303.004338 2063.554109 2198.186695 1910.612248 1501.646529 1053.902669 613.8488925 1877.389789 1917.412307 1.243291778 1.201100217 1.076218245 1.146434018 0.996453523 0.783163081 0.549648433 0.320144442 0.979126806 1 10.90494488 -4.80461107 1.129381001 1.125854583 0.245514325 0.919582924 0.07969279 0.174876425 0.311096546 0.014875589 0.144704073 1.57E-05 4.80461107 -0.880340257 down DLFDLNS(ph)SEEDDTEGFSER ddPTM_HeLa_Curcumin_4h_R1 1 DLFDLNSSEEDDTEGFSER 19 0 Q9Y3T9 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 1 0 DLFDLNS(0.5)S(0.5)EEDDTEGFSER 295.16 2.40E-83 43381000 4168 3288.7 4058.3 3460.3 3595.3 4664.6 3222.6 2024.4 3806.1 3740.2 TRUE FALSE FALSE 3838.098402 3572.960574 4208.704168 3445.982195 3552.428396 3697.109379 3313.017483 2641.630241 3388.580352 3870.171672 0.991712701 0.923204673 1.087472217 0.890395178 0.917899436 0.955283045 0.856038895 0.682561515 0.875563319 1 11.91818185 -3.447179779 0.682539071 0.99176079 4.32E-12 0.622060053 0.062733134 2.514552579 0.367982849 0.007968176 2.509640931 0.000357125 3.447179779 -0.99176079 DLFDLNSS(ph)EEDDTEGFSER ddPTM_HeLa_Curcumin_4h_R1 1 DLFDLNSSEEDDTEGFSER 19 0 Q9Y3T9 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 1 0 DLFDLNS(0.004)S(0.996)EEDDTEGFSER 144.17 0.00015274 57872000 805.85 630.39 700.54 940.18 954.8 1011.5 743.46 510.28 705.61 635.84 TRUE FALSE FALSE 742.0661222 684.8781026 726.5026287 936.2897843 943.4146336 801.703498 764.3194867 665.862023 628.2063483 657.9353927 1.127870807 1.040950389 1.104215758 1.423072531 1.433901632 1.218514017 1.161693831 1.012047734 0.954814645 1 9.361802112 -6.498623502 22.38406889 1.061183114 1.254454432 0.412701888 0.122149436 174.9614378 161463.5395 0.019722487 0.029993638 3.17E-07 6.498623502 0.193271318 DLFDPIIEDR ddPTM_HeLa_Curcumin_4h_R1 2 DLFDPIIEDR 10 0 P12277;G3V4N7;G3V461 P12277 CKB Creatine kinase B-type 0 0 ; ; 154.56 0.0055034 15285100 3157.3 2882.8 2757.6 3113.7 3592.8 3728.9 2919.9 2682.57 3087.02 3259.3 FALSE FALSE TRUE 2907.396373 3131.976386 2859.799082 3100.816334 3549.958207 2955.484107 3001.824535 3500.473244 2748.381629 3372.560432 0.862073914 0.928664274 0.847960812 0.919424988 1.052600325 0.876332438 0.890072868 1.037927508 0.814924353 1 11.71962858 DLFDYS(ph)PPLHK ddPTM_HeLa_Curcumin_4h_R1 2 DLFDYSPPLHK 11 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 DLFDYS(1)PPLHK;DLFDYS(1)PPLHK ; 82.515 0.01196 342372700 9251.1 8872.4 9193.5 9863 8920.1 9651.7 8643.8 9037.7 9307.3 10347.5 TRUE FALSE FALSE 8518.865673 9639.290721 9534.219197 9822.189519 8813.733633 7649.828623 8886.321764 11793.25313 8286.312476 10707.07485 0.795629599 0.90027303 0.89045975 0.917355081 0.823169143 0.714464849 0.829948598 1.101444912 0.773910016 1 13.38627677 -9.502692169 1.228728539 1.000610637 0.858597946 0 0.118382078 0.566639003 1.520505024 0.068083712 0.016197418 3.14E-10 9.502692169 -0.142012691 DLFPYEESK(ac)EK ddPTM_HeLa_Curcumin_4h_R1 1 DLFPYEESKEK 11 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 0 1 DLFPYEESK(1)EK 133.42 0.00059339 1238100 2197.3 1876.2 1474.5 1555.3 1884.7 3055.4 2243.6 1751.7 2644.8 1632.8 FALSE TRUE FALSE 2023.381386 2038.370368 1529.146267 1548.864581 1862.226183 2421.675599 2306.549378 2285.785266 2354.672057 1689.539678 1.197593293 1.206464929 0.905066798 0.916737618 1.102209204 1.433334552 1.365193968 1.352904164 1.393676684 1 10.72241452 -5.293736525 7.510030195 1.076203784 1.381966324 0.448395055 0.140496183 0.122619692 24.63889397 0.016967672 0.038630221 5.08E-06 5.293736525 0.30576254 DLFSLDSEDPSPAS(ph)PPLR ddPTM_HeLa_Curcumin_4h_R1 4 DLFSLDSEDPSPASPPLR 18 0 H3BTX0;Q9BTK6 H3BTX0 PAGR1 PAXIP1-associated glutamate-rich protein 1 1 0 DLFSLDSEDPS(0.013)PAS(0.987)PPLR;DLFSLDSEDPSPAS(1)PPLR;DLFSLDSEDPSPAS(1)PPLR;DLFSLDSEDPSPAS(1)PPLR ;;; 235.02 3.94E-24 178891700 8123.72 7032.95 7035.4 7012.8 7144.01 9563.8 6695.8 4875.99 8199.4 7449.14 TRUE FALSE FALSE 7480.71899 7640.84686 7296.138113 6983.782892 7058.822347 7580.160074 6883.666127 6362.656905 7299.946334 7707.997061 0.970513991 0.991288243 0.946567319 0.906043793 0.915779066 0.983415019 0.893055105 0.825461771 0.94706138 1 12.91214031 -1 0.258719968 0.995021745 0.021244484 0.588860949 0.032794562 20.34372982 0.255926728 0.015582523 8.82888911 0.1 1 -0.973777261 DLGGFDEDAEPRR ddPTM_HeLa_Curcumin_4h_R1 1 DLGGFDEDAEPRR 13 1 H0Y3T6;G3V1E2;A0A5F9UJX7;A0A5F9UP49;Q9BRK5-4;Q9BRK5-3;Q9BRK5-6;Q9BRK5 H0Y3T6 SDF4 45 kDa calcium-binding protein 0 0 96.604 0.0051528 0 788.85 676.64 652.36 744.07 699.95 1004 858.97 3844.5 973.77 643.71 FALSE FALSE TRUE 726.4116901 735.1257466 676.5370355 740.9912355 691.6035534 795.7590826 883.0703864 5016.670352 866.9498673 666.0788746 1.090579086 1.103661705 1.015701085 1.112467703 1.038320805 1.19469197 1.325774499 7.531646091 1.301572382 1 9.379549216 -4.260610209 5.172021672 1.064393011 7.822450619 0.997694467 0.092334925 0.00400256 0.35615495 0.010179126 0.095933747 5.49E-05 4.260610209 6.758057608 up DLGHPVEEEDELES(ph)GDQEDEDDESEDPGKDLDHI ddPTM_HeLa_Curcumin_4h_R1 2 DLGHPVEEEDELESGDQEDEDDESEDPGKDLDHI 34 1 O60763;O60763-2 O60763 USO1 General vesicular transport factor p115 1 0 DLGHPVEEEDELES(0.957)GDQEDEDDES(0.043)EDPGKDLDHI;DLGHPVEEEDELES(1)GDQEDEDDESEDPGKDLDHI ; 111.95 7.76E-15 179053000 5684.1 4894.1 5057.8 4964.5 5241.4 5552.1 3347.2 2852.9 5088.9 4702 TRUE FALSE FALSE 5234.197487 5317.124196 5245.246517 4943.958214 5178.899728 4400.531875 3441.113423 3722.736077 4530.660402 4865.39415 1.075801328 1.092845519 1.07807227 1.016147523 1.064435803 0.904455372 0.707263033 0.765145837 0.931201104 1 12.24834097 -4.981000695 2.957589143 1.044145013 0.735413405 0.859568008 0.048324639 0.051764424 0.916290706 0.005726784 0.019454125 1.04E-05 4.981000695 -0.308731608 DLGHPVEEEDELESGDQEDEDDESEDPGKDLDHI ddPTM_HeLa_Curcumin_4h_R1 2 DLGHPVEEEDELESGDQEDEDDESEDPGKDLDHI 34 1 O60763;O60763-2 O60763 USO1 General vesicular transport factor p115 0 0 ; ; 85.712 2.95E-08 9738700 2866.4 2311 2233.77 2603.4 2513.3 2550.8 2156.1 2082.94 2324 2639.3 FALSE FALSE TRUE 2639.521415 2510.752542 2316.555481 2592.627821 2483.330539 2021.735327 2216.594363 2718.018817 2069.063014 2731.015479 0.966498153 0.919347606 0.848239602 0.949327399 0.909306651 0.740287026 0.811637422 0.995241088 0.757616729 1 11.41522178 -7.062165837 0.712724941 0.993941923 0.858739333 0 0.100476159 0.466071812 0.489676334 0.017007251 0.023176909 8.67E-08 7.062165837 -0.135202591 DLGSTEDGDGT(ph)DDFLT(ph)DKEDEK ddPTM_HeLa_Curcumin_4h_R1 1 DLGSTEDGDGTDDFLTDKEDEK 22 1 Q15527 Q15527 SURF2 Surfeit locus protein 2 2 0 DLGS(0.07)T(0.017)EDGDGT(0.913)DDFLT(1)DKEDEK 89.079 0.00024338 11197000 5822.7 5864.1 7019.6 6087.7 6852.6 6647.1 6459.1 2882.8 5916.3 5084 TRUE FALSE FALSE 5361.827151 6370.966674 7279.752551 6062.51071 6770.887221 5268.416532 6640.324962 3761.752449 5267.296692 5260.668622 1.019229215 1.211056452 1.383807473 1.152422087 1.28707731 1.0014728 1.262258743 0.715071167 1.001259929 1 12.36103046 -7.307131639 8.805101529 1.008957746 1.158677186 0.113109191 0.173903086 0.569828547 105.3676877 0.027838036 0.031847768 4.93E-08 7.307131639 0.14971944 DLGSTEDGDGT(ph)DDFLT(ph)DKEDEKAKPPR ddPTM_HeLa_Curcumin_4h_R1 1 DLGSTEDGDGTDDFLTDKEDEKAKPPR 27 3 Q15527 Q15527 SURF2 Surfeit locus protein 2 2 0 DLGS(0.052)T(0.135)EDGDGT(0.824)DDFLT(0.989)DKEDEKAKPPR 52.654 0.0042986 17590000 2470.4 2157.6 1889.2 2365.5 2321.5 2898 2408.6 1732.9 2804.7 2570.4 TRUE FALSE FALSE 2274.865233 2344.09333 1959.215414 2355.712188 2293.817629 2296.922133 2476.178834 2261.253233 2497.031427 2659.721209 0.855302137 0.881330465 0.736624353 0.885698915 0.862427844 0.863595074 0.930991874 0.850184307 0.938832017 1 11.37705932 -9.099449402 0.792837512 1.003327402 0.858329278 0.425894794 0.049758609 0.395148841 0.436024401 0.03487481 0.009455976 7.95E-10 9.099449402 -0.144998123 DLGSTEDGDGT(ph)DDFLTDKEDEK ddPTM_HeLa_Curcumin_4h_R1 3 DLGSTEDGDGTDDFLTDKEDEK 22 1 Q15527 Q15527 SURF2 Surfeit locus protein 2 1 0 DLGST(0.002)EDGDGT(0.998)DDFLTDKEDEK;DLGSTEDGDGT(1)DDFLTDKEDEK;DLGSTEDGDGT(1)DDFLTDKEDEK ;; 151 3.15E-06 291965000 10018.3 7442.8 9742 9171.5 10543.1 10179 7985.5 3621.39 9163.4 9068.9 TRUE FALSE FALSE 9225.340984 8086.122468 10103.04709 9133.550763 10417.38042 8067.760659 8209.551638 4725.53514 8158.197946 9384.0436 0.983088035 0.861688501 1.076619794 0.973306514 1.11011637 0.859731796 0.874841592 0.503571311 0.869369143 1 13.195994 -3.983721155 1.303881673 0.991760494 6.22E-19 0.745164208 0.081112447 0.720682635 0.654448411 0.009523118 1.126908551 0.000103819 3.983721155 -0.991760494 MYFPDVEFDIKS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 MYFPDVEFDIKSPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 MYFPDVEFDIKS(1)PK 83.894 0.0067962 343740000 4144.9 3311.2 4009.7 3422.3 3515.2 5013.6 5562.1 6315.9 4385.1 2811.4 TRUE FALSE FALSE 3816.826791 3597.405374 4158.303009 3408.139429 3473.283536 3973.722845 5718.157556 8241.588835 3904.065501 2909.095941 1.31203194 1.236605958 1.429414187 1.171545903 1.19393915 1.365964865 1.96561326 2.833041262 1.342020195 1 11.50635516 -4.344353439 1.418487526 1.179936791 3.360738109 0.944576506 0.119943247 0.188198654 0.375571911 0.021355539 0.55471427 4.53E-05 4.344353439 2.180801319 up DLGSTEDGDGTDDFLT(ph)DKEDEKAKPPR ddPTM_HeLa_Curcumin_4h_R1 1 DLGSTEDGDGTDDFLTDKEDEKAKPPR 27 3 Q15527 Q15527 SURF2 Surfeit locus protein 2 1 0 DLGST(0.001)EDGDGT(0.042)DDFLT(0.957)DKEDEKAKPPR 47.554 0.0081482 10417000 1517.2 1008.4 1172.2 1253.8 992.14 1477.6 1237 1665.2 1352 1090.7 TRUE FALSE FALSE 1397.112019 1095.561603 1215.642763 1248.612108 980.3093785 1171.129104 1271.706891 2172.911814 1203.688983 1128.601744 1.237914106 0.970724712 1.077122882 1.106335441 0.868605231 1.037681459 1.126798623 1.925313182 1.066531209 1 10.14032077 -4.261767349 4.852374673 1.080099865 1.970647494 0.882081715 0.095244927 0.0525887 3.606218277 0.016171769 0.157275763 5.47E-05 4.261767349 0.890547629 DLGYSNYGPS(ph)IAYQTK ddPTM_HeLa_Curcumin_4h_R1 1 DLGYSNYGPSIAYQTK 16 0 O94991-2;O94991 O94991-2 SLITRK5 SLIT and NTRK-like protein 5 1 0 DLGY(0.005)S(0.006)NY(0.005)GPS(0.983)IAY(0.001)QTK 74.962 0.018389 61189000 2587.4 1913.3 2568 2541.2 2590.5 3174.4 2559.7 2720.3 2510.8 2722.7 TRUE FALSE FALSE 2382.60456 2078.677127 2663.172339 2530.685188 2559.609979 2515.993657 2631.518293 3549.706947 2235.371522 2817.313622 0.845700862 0.73782241 0.945287851 0.898261794 0.908528592 0.893047063 0.934052309 1.259961589 0.793440781 1 11.46010446 -4.261396598 4.337731027 0.908322125 1.285794131 0.685182903 0.075034956 0.10315615 4.585290677 0.011126799 0.119539571 5.48E-05 4.261396598 0.377472006 DLHILPPPLIPT(ph)PPPDDPR ddPTM_HeLa_Curcumin_4h_R1 1 DLHILPPPLIPTPPPDDPR 19 0 E9PK26;E9PMW6;Q9NRS6-2;Q9NRS6 E9PK26 SNX15 Sorting nexin-15 1 0 DLHILPPPLIPT(1)PPPDDPR 94.61 0.0043185 1897100 1448.7 1306.6 1125.6 1220.6 1218.6 1391.6 1129.4 1058.1 1183.5 1397.9 TRUE FALSE FALSE 1334.033866 1419.536682 1167.315726 1215.549481 1204.068991 1102.966473 1161.087924 1380.709819 1053.673011 1446.476921 0.92226419 0.981375272 0.807006119 0.840351798 0.832414934 0.762519234 0.802700622 0.954532906 0.728440942 1 10.49832759 -6.762516787 24.9998283 0.963622037 0.828934693 0.011561446 0.08953024 14.57812557 338270.4261 0.008437309 0.011446256 1.73E-07 6.762516787 -0.134687344 DLHQGIEAAS(ph)DEEDLR ddPTM_HeLa_Curcumin_4h_R1 2 DLHQGIEAASDEEDLR 16 0 A0A0C4DGG1;Q9UKS6;E9PIY1 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 0 DLHQGIEAAS(1)DEEDLR;DLHQGIEAAS(1)DEEDLR ; 174.35 4.21E-16 5582600 2920.84 2850 2871.87 2747.09 3133.79 4111.27 3006.68 2313.24 2912.69 2655.12 TRUE FALSE FALSE 2689.652432 3096.341301 2978.304029 2735.723269 3096.421601 3258.546258 3091.039349 3018.536227 2593.175194 2747.385222 0.978986278 1.127013888 1.084050392 0.995755254 1.127043116 1.186053645 1.12508407 1.098694207 0.943870256 1 11.4238435 -6.618555565 0.657323155 0.987790798 1.134788134 0.551808292 0.05121371 0.394989325 0.346649493 0.012475372 0.024003806 2.41E-07 6.618555565 0.146997336 DLHQGIEAASDEEDLRWWR ddPTM_HeLa_Curcumin_4h_R1 1 DLHQGIEAASDEEDLRWWR 19 1 A0A0C4DGG1;Q9UKS6;E9PIY1 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 0 0 75.445 0.0031403 5697600 1430.6 1189.5 987.86 1280.3 915.29 2214.5 1314.1 1508 1705.6 1441.3 FALSE FALSE TRUE 1317.3665 1292.31508 1024.470961 1275.002458 904.3757645 1755.187737 1350.970109 1967.782258 1518.499947 1491.385068 0.88331748 0.866520061 0.686925854 0.854911642 0.606399906 1.176884344 0.905849293 1.319432721 1.018181005 1 10.54243709 -2.864694393 1.171459932 0.899255878 10.23381182 0.415921134 0.153133421 28.43159625 2.08631973 0.02250257 637.892274 0.001365544 2.864694393 9.334555946 DLIDFDDR ddPTM_HeLa_Curcumin_4h_R1 1 DLIDFDDR 8 0 P15924-2;P15924-3;P15924 P15924-2 DSP Desmoplakin 0 0 148.99 0.017491 7694200 5558.7 4945.5 5625.2 5685.7 6043.8 5508.6 4072.4 2703 5554.1 4599.3 FALSE FALSE TRUE 5118.723029 5372.966983 5833.67486 5662.17408 5971.731632 4366.054265 4186.660584 3527.132257 4944.829126 4759.125333 1.075559619 1.128982031 1.225787188 1.189750991 1.254796042 0.917406868 0.879712193 0.741130357 1.039020572 1 12.21648073 -4.92030409 2.898308773 1.08275958 0.802205648 0.649901165 0.092356055 0.159777174 2.670360925 0.015527038 0.056523048 1.20E-05 4.92030409 -0.280553932 DLIDNS(ph)FNR ddPTM_HeLa_Curcumin_4h_R1 3 DLIDNSFNR 9 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 0 DLIDNS(1)FNR;DLIDNS(1)FNR;DLIDNS(1)FNR ;; 111.52 0.0086577 46730600 6667 5781.8 5332.3 6665.6 6692.1 6926.9 7230.8 3667.07 7150.8 5466.3 TRUE FALSE FALSE 6139.299915 6281.553029 5529.919729 6638.019513 6612.301078 5490.182858 7433.676787 4785.142762 6366.37513 5656.253518 1.085400415 1.110550121 0.977664758 1.173571781 1.169024878 0.97063946 1.314240383 0.845991564 1.125546284 1 12.46563107 -9.149660718 0.562219259 0.987043095 1.091253201 0 0.128718516 2.587688108 1.232235753 0.140898579 0.026904456 7.08E-10 9.149660718 0.104210106 DLIEDSSVQKDGLNQTTIPVS(ph)PPSTTKPSR ddPTM_HeLa_Curcumin_4h_R1 2 DLIEDSSVQKDGLNQTTIPVSPPSTTKPSR 30 2 X6RLN4;Q71RC2-2;Q71RC2-6;Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4 X6RLN4 LARP4 La-related protein 4 1 0 DLIEDSSVQKDGLNQT(0.001)T(0.001)IPVS(0.968)PPS(0.009)T(0.009)T(0.009)KPS(0.002)R;DLIEDSSVQKDGLNQT(0.056)T(0.188)IPVS(0.66)PPS(0.03)T(0.03)T(0.03)KPS(0.005)R ; 93.876 2.43E-08 91422000 4254 3294.6 3065.5 3790.1 2861.9 4414.8 2903.3 3349.7 4422.3 3904.1 TRUE FALSE FALSE 3917.291411 3579.370544 3179.110127 3774.41757 2827.773712 3499.120715 2984.758784 4371.00811 3937.184754 4039.767184 0.969682467 0.886033868 0.786953797 0.934315617 0.699984326 0.866168904 0.738844257 1.081995053 0.974606846 1 11.98005644 -7.20620359 2.753226861 0.987188802 0.84321886 0.248087133 0.100542447 0.232979842 3.426000693 0.015870437 0.019207626 6.22E-08 7.20620359 -0.143969943 DLIGIAK ddPTM_HeLa_Curcumin_4h_R1 1 DLIGIAK 7 0 Q7L014;A0A0C4DG89;D6RJA6 Q7L014 DDX46 Probable ATP-dependent RNA helicase DDX46 0 0 103.29 0.018437 1158400 1915.2 1499 1602.1 1788.4 1621.1 2124.2 1656.2 1774.7 1571.9 1711.6 FALSE FALSE TRUE 1763.609899 1628.566881 1661.475235 1781.000075 1601.769441 1683.616975 1702.668515 2315.79786 1399.466503 1771.077973 0.995783317 0.919534264 0.938115239 1.005602295 0.904403683 0.950617083 0.961374113 1.307564035 0.790177804 1 10.79041201 -4.259681397 24.98122551 0.978021869 1.307564147 0.692121738 0.069502323 41.03998186 583134.3446 0.005646 0.048526042 5.50E-05 4.259681397 0.329542277 DLIHDQDEDEEEEEGQR ddPTM_HeLa_Curcumin_4h_R1 2 DLIHDQDEDEEEEEGQR 17 0 F2Z2K0;Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;R4GNE6 F2Z2K0 NSFL1C NSFL1 cofactor p47 0 0 ; ; 186.77 1.49E-06 93661000 10967.1 9385.2 9433.8 9555.5 10651.6 15583.9 13282.5 8419.4 11939.8 8199.6 FALSE FALSE TRUE 10099.04246 10196.41487 9783.424927 9515.961873 10524.58663 12351.62347 13655.1712 10986.4363 10630.03381 8484.53549 1.190288198 1.201764655 1.153089045 1.121565451 1.240443468 1.455780754 1.609418832 1.294877759 1.25287163 1 13.05061996 -1 0.144186969 0.950714527 2.903358887 0.395194174 0.127285292 33.20605748 0.31353647 0.272747394 13.50084612 0.1 1 1.95264436 DLIQAAQK(ac)QMAHAVR ddPTM_HeLa_Curcumin_4h_R1 1 DLIQAAQKQMAHAVR 15 1 E7EWD6;Q76L83;Q76L83-2 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 0 1 DLIQAAQK(1)QMAHAVR 115.26 0.00073711 1692500 479.67 352.2 619.47 559.01 438.12 783.2 530.77 255.67 585.28 591.43 FALSE TRUE FALSE 441.7036134 382.6425986 642.4281031 556.6969647 432.8957051 620.7554915 545.6619777 333.622606 521.0762483 611.9821485 0.721758983 0.625251242 1.049749743 0.909662097 0.707366557 1.014335946 0.891630547 0.545150879 0.851456615 1 9.25734576 -9.4996654 1.279018948 0.998837781 0.808901937 0.050646964 0.160564613 0.635782504 1.879290703 0.103347598 0.025726442 3.16E-10 9.4996654 -0.189935843 DLISHDEMFSDIYK ddPTM_HeLa_Curcumin_4h_R1 2 DLISHDEMFSDIYK 14 0 A0A0B4J2C3;Q5W0H4;P13693 A0A0B4J2C3 TPT1 Translationally-controlled tumor protein 0 0 ; ; 183.89 6.00E-05 227170000 17130 13085.1 15124.3 14082.8 15099 20229.5 14510.5 14876.1 16892.1 14660.8 FALSE FALSE TRUE 15774.14242 14216.11774 15684.81986 14024.52911 14918.95429 16033.67367 14917.62558 19411.75441 15039.07889 15170.26171 1.039806875 0.937104317 1.033918871 0.924475093 0.983434207 1.05691477 0.98334662 1.279592586 0.991352633 1 13.88895835 -4.258411087 24.75845079 1.006832542 1.279592701 0.805268824 0.041664572 81.95987418 670040.0809 0.005676981 0.053630107 5.52E-05 4.258411087 0.272760158 AVS(ph)PPHLDGPPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 AVSPPHLDGPPSPR 14 0 P29590;P29590-5;P29590-4;P29590-9;P29590-3;P29590-8;P29590-11;H3BVD2;P29590-12;H3BT57;P29590-13;H3BRN3;H3BUJ5;P29590-2 P29590;P29590-2 PML Protein PML 2 0 AVS(1)PPHLDGPPS(1)PR 152.68 0.0010714 72097000 3576.1 2717.1 3026.5 2999.3 3495.7 3339.8 1670.6 1020.2 3315.1 3001.2 TRUE FALSE FALSE 3293.047912 2951.954017 3138.664752 2986.889691 3454.016061 2647.087833 1717.47254 1331.254284 2951.441824 3105.491477 1.060395089 0.950559368 1.010682134 0.961809013 1.112228479 0.852389341 0.553043714 0.428677487 0.950394437 1 11.60060589 -4.802253982 2.383065864 1.021546261 0.443489344 0.939278407 0.051998703 0.041435728 0.455214819 0.006632422 0.031202499 1.58E-05 4.802253982 -0.578056917 down VEQMPQAS(ph)PGLAPR ddPTM_HeLa_Curcumin_4h_R1 2 VEQMPQASPGLAPR 14 0 Q8N3F8;H0Y6J8 Q8N3F8 MICALL1 MICAL-like protein 1 1 0 VEQMPQAS(1)PGLAPR;VEQMPQAS(1)PGLAPR ; 137.27 0.00085406 91827000 6912.2 5804.7 6285 6887 6302.4 5678.1 3198.2 1370.51 7266.6 6059.1 TRUE FALSE FALSE 6365.092076 6306.432403 6517.927629 6858.503419 6227.247996 4500.398055 3287.932884 1788.37219 6469.47216 6269.653274 1.015222341 1.005866214 1.039599376 1.093920687 0.993236424 0.717806529 0.52442021 0.285242598 1.031870803 1 12.61416995 -4.802163195 1.460612291 1.017843155 0.276022066 0.976158591 0.039705847 0.057273824 0.198581113 0.006215991 0.046060803 1.58E-05 4.802163195 -0.741821089 down DLK(ac)DYFTK ddPTM_HeLa_Curcumin_4h_R1 1 DLKDYFTK 8 1 Q99729-3;Q99729-4;D6R9P3;D6RD18;D6RBZ0;Q99729-2;Q99729 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 0 1 DLK(1)DYFTK 94.309 0.0064456 0 492.66 693.33 462.46 426.65 818.57 856.1 700.09 746.06 1181 553.21 FALSE TRUE FALSE 453.6654411 753.2583558 479.5991744 424.8846353 808.8090874 678.5352098 719.7326412 973.5302596 1051.447255 572.4340063 0.792520074 1.315886805 0.837824394 0.742242129 1.412929837 1.185350979 1.257319854 1.700685579 1.836800824 1 9.16096557 -1.814857095 0.439313041 0.912857476 8.440119213 0.027020242 0.350769127 18.21796642 0.410465198 0.043391937 112.5068608 0.015315913 1.814857095 7.527261737 DLKIESDVQEPT(ph)EPEDDLDIMLGNK ddPTM_HeLa_Curcumin_4h_R1 2 DLKIESDVQEPTEPEDDLDIMLGNK 25 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 0 DLKIES(0.027)DVQEPT(0.973)EPEDDLDIMLGNK;DLKIES(0.062)DVQEPT(0.938)EPEDDLDIMLGNK ; 50.536 0.011581 31486000 5771.5 4966.9 5195.5 6390 5653.6 8659.7 10359.7 5047.7 6635.8 5854.8 TRUE FALSE FALSE 5314.679685 5396.216704 5388.0498 6363.559873 5586.184512 6863.580605 10650.3653 6586.720493 5907.869342 6058.253864 0.877262625 0.890721456 0.889373394 1.05039505 0.922078315 1.132930504 1.757992573 1.087230849 0.97517692 1 12.56468632 -4.980499839 9.657777772 0.943156243 1.429120386 0.591004946 0.158506903 0.12141159 55.21270583 0.019509144 0.05794125 1.05E-05 4.980499839 0.485964143 DLLEEEEAWEASHKNDLQDTEIS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 DLLEEEEAWEASHKNDLQDTEISPR 25 1 Q9NS91 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 0 DLLEEEEAWEAS(0.007)HKNDLQDT(0.321)EIS(0.672)PR;DLLEEEEAWEAS(0.026)HKNDLQDT(0.241)EIS(0.733)PR ; 42.825 0.017974 12769200 3811.2 3705.4 3716.9 3641.9 3897.3 4082.7 3408 1868.46 3394.2 3196.7 TRUE FALSE FALSE 3509.539498 4025.678265 3854.651584 3626.830783 3850.827243 3235.901998 3503.619308 2438.144853 3021.864752 3307.785087 1.060993809 1.217031385 1.165327094 1.09645297 1.164170931 0.978268513 1.059204034 0.737092885 0.913561393 1 11.69164979 -4.260174958 6.507057814 1.062890945 0.730460883 0.55980312 0.088916782 0.069893455 17.63816225 0.011869672 0.100944567 5.49E-05 4.260174958 -0.332430061 DLLHNEDRHDDYFQER ddPTM_HeLa_Curcumin_4h_R1 4 DLLHNEDRHDDYFQER 16 1 Q8N684-2;Q8N684;Q8N684-3 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 0 0 ;;; ;;; 99.927 0.001352 40295700 10080.4 8461.3 8080.3 9266.7 9059.3 11086.4 8547 7961.8 11000.8 9441.5 FALSE FALSE TRUE 9282.525703 9192.657069 8379.763026 9228.356851 8951.273764 8786.955671 8786.805817 10389.31617 9794.039763 9769.591422 0.95014472 0.940945908 0.857739353 0.944600081 0.916238293 0.899418951 0.899403612 1.06343405 1.002502494 1 13.25408251 -8.28375604 0.831653266 0.993754531 0.927579196 0.212271614 0.050938859 0.584774867 0.859817636 0.017874149 0.01091875 5.20E-09 8.28375604 -0.066175335 DLLHPS(ph)PEEEK ddPTM_HeLa_Curcumin_4h_R1 3 DLLHPSPEEEK 11 0 P42677 P42677 RPS27 40S ribosomal protein S27 1 0 DLLHPS(1)PEEEK;DLLHPS(1)PEEEK;DLLHPS(1)PEEEK ;; 102.9 0.0044087 184819000 20151.5 18296.8 19824.7 20865.4 22972.8 20051.8 15090.3 12875.2 17455.4 16481.4 TRUE FALSE FALSE 18556.48751 19878.29386 20559.42082 20779.0645 22698.86436 15892.83065 15513.6932 16800.78921 15540.58629 17054.12742 1.088093636 1.165600172 1.205539299 1.218418509 1.33098949 0.931905236 0.909673818 0.98514505 0.911250743 1 14.05783332 DLLHPS(ph)PEEEKR ddPTM_HeLa_Curcumin_4h_R1 1 DLLHPSPEEEKR 12 1 P42677 P42677 RPS27 40S ribosomal protein S27 1 0 DLLHPS(1)PEEEKR 85.163 0.0092565 17953000 2514.1 2181.4 1797.6 1856.7 2210.1 2425.5 1664.4 1703 2002.7 1897.7 TRUE FALSE FALSE 2315.106332 2369.950496 1864.220637 1849.017467 2183.746001 1922.423959 1711.098584 2222.23686 1783.008821 1963.644934 1.17898419 1.206913967 0.949367477 0.941625156 1.112088017 0.979007929 0.871388995 1.131689758 0.908009788 1 10.93931837 -6.734492823 24.99652338 1.09606148 0.99361873 0.091227155 0.108013619 282.698887 262240.3156 0.016173399 0.022869257 1.84E-07 6.734492823 -0.10244275 DLLIAYYDVDYEK ddPTM_HeLa_Curcumin_4h_R1 2 DLLIAYYDVDYEK 13 0 P30101 P30101 PDIA3 Protein disulfide-isomerase A3 0 0 ; ; 206.1 4.34E-08 33179000 4540 4539.3 4105.2 4548.9 4185 6054.5 4442 2864.3 4839.9 4253.3 FALSE FALSE TRUE 4180.654209 4931.656865 4257.342323 4530.077857 4135.096608 4798.728452 4566.630565 3737.611884 4308.975079 4401.101858 0.949910805 1.120550495 0.967335558 1.029305388 0.939559397 1.090347055 1.037610742 0.849244577 0.979067338 1 12.10364905 -1.014800982 21.51407553 0.990390043 0.001982288 0 0.074547821 0 0 0.009152515 0 0.096649368 1.014800982 -0.988407755 DLLSDLQDIS(ph)DSER ddPTM_HeLa_Curcumin_4h_R1 5 DLLSDLQDISDSER 14 0 Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;J3KS35;E7ESP2;P21127-5;P21127-10;A0A0D9SEI3;A0A0D9SER5;A0A0D9SEN2;P21127-6;P21127-9;P21127-8;P21127-3;P21127-2;P21127;Q9UQ88-9 Q5QPR4;A0A0D9SEI3 CDK11A;CDK11B Cyclin-dependent kinase 11A;Cyclin-dependent kinase 11B 1 0 DLLSDLQDIS(0.966)DS(0.034)ER;DLLSDLQDIS(0.677)DS(0.323)ER;DLLSDLQDIS(1)DSER;DLLSDLQDIS(0.998)DS(0.002)ER;DLLSDLQDIS(0.987)DS(0.013)ER ;;;; 215.37 8.36E-14 173549600 9986.7 8106.5 8577.2 9137.7 10039.2 11146.6 8461.8 5779.33 8991.6 8388.2 TRUE FALSE FALSE 9196.242157 8807.189738 8895.078577 9099.890619 9919.489097 8834.669512 8699.215334 7541.421112 8005.243976 8679.689326 1.059512825 1.014689513 1.024815318 1.04841202 1.142839188 1.017855499 1.002249621 0.868858415 0.922296142 1 13.08342769 -4.238914747 2.302992625 1.036420983 0.821882442 0.451074069 0.052205106 0.346100989 2.031566552 0.005863174 0.15233488 5.77E-05 4.238914747 -0.214538541 GQVSES(ph)EDSITK ddPTM_HeLa_Curcumin_4h_R1 3 GQVSESEDSITK 12 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 0 GQVS(0.331)ES(0.669)EDSITK;GQVS(0.323)ES(0.671)EDS(0.006)ITK;GQVS(0.047)ES(0.892)EDS(0.059)IT(0.002)K ;; 143.46 0.00098396 60016400 9037.2 6302.2 6217.1 7621 8031.1 7499.7 3197.66 1650.97 8584.1 6686 TRUE FALSE FALSE 8321.896084 6846.934086 6447.511195 7589.466321 7935.334378 5944.177681 3287.377734 2154.343153 7642.445706 6918.338002 1.202875037 0.989679036 0.931945099 1.09700716 1.1470001 0.859191569 0.475168709 0.311396054 1.104664979 1 12.75620978 -4.800240205 2.206001204 1.080266767 0.322764743 0.921925254 0.078021951 0.07299954 0.67688356 0.014074229 0.070477549 1.58E-05 4.800240205 -0.757502024 down DLLVQYATGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 DLLVQYATGKK 11 1 E7EW05;Q9NVU7-2;Q9NVU7 E7EW05 SDAD1 Protein SDA1 homolog 0 1 DLLVQYATGK(1)K 167.18 3.43E-09 595580 598.2 647.28 842.59 745.85 729.49 850.26 995.79 609.9 927.94 743.7 FALSE TRUE FALSE 550.8518388 703.227999 873.8171266 742.7638703 720.7913082 673.9064916 1023.729187 795.8557024 826.1473036 769.5435196 0.715816357 0.91382486 1.135500598 0.965200604 0.936647883 0.875722392 1.330307073 1.034191936 1.073555013 1 9.587859107 -4.957260942 0.619353245 0.879243143 1.22367908 0.054354951 0.151545635 1.829434455 0.777743015 0.030449706 0.379822971 1.10E-05 4.957260942 0.344435936 EIQNGNLHES(ph)DSESVPR ddPTM_HeLa_Curcumin_4h_R1 2 EIQNGNLHESDSESVPR 17 0 Q86UP2-2;Q86UP2-3;Q86UP2-4;Q86UP2 Q86UP2-2 KTN1 Kinectin 1 0 EIQNGNLHES(0.786)DS(0.21)ES(0.004)VPR;EIQNGNLHES(0.998)DS(0.002)ES(0.001)VPR ; 229.48 3.91E-22 43918000 2886.61 2761.36 2431.21 3031.14 2939.46 3263.61 1375.92 884.3 3995.5 3335.72 TRUE FALSE FALSE 2658.131773 3000.039654 2521.312781 3018.597946 2904.408859 2586.700498 1414.524612 1153.918999 3557.203646 3451.636022 0.770107785 0.869164545 0.730468904 0.874541211 0.841458613 0.749412882 0.409812797 0.334310742 1.030584808 1 11.75306462 -4.796153375 2.185519501 0.871221906 0.323828722 0.843000267 0.085663771 0.101920198 0.924673218 0.014004828 0.071116202 1.60E-05 4.796153375 -0.547393184 down DLMVGDEASELR ddPTM_HeLa_Curcumin_4h_R1 3 DLMVGDEASELR 12 0 P61160 P61160 ACTR2 Actin-related protein 2 0 0 ;; ;; 194.12 6.30E-07 41133000 4111.86 3719.71 3455.98 3674.96 4013.76 4343.05 3307.35 3057.96 3767.84 3711.11 FALSE FALSE TRUE 3786.401942 4041.225158 3584.061659 3659.753989 3965.898533 3442.252474 3400.14534 3990.317927 3354.517379 3840.070796 0.986023994 1.052382983 0.933332183 0.953043364 1.032767036 0.896403388 0.885438191 1.039126136 0.873556129 1 11.90691719 -6.127802403 0.971740557 0.996199778 0.947453223 0 0.065262426 0.830098433 1.542885779 0.008923467 0.021108338 7.45E-07 6.127802403 -0.048746556 DLNES(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 2 DLNESPVK 8 0 Q96RL1-2;Q96RL1;Q96RL1-3;Q96RL1-4 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 0 DLNES(1)PVK;DLNES(1)PVK ; 106.67 0.012269 428430000 13078.5 12169.3 13119.1 12405.8 14156.1 13229.3 11206 5105.3 11201.4 10858.1 TRUE FALSE FALSE 12043.32292 13221.16007 13605.30539 12354.46809 13987.29775 10485.39406 11520.4102 6661.882468 9972.634445 11235.41817 1.071906959 1.176739474 1.210930041 1.099600202 1.244928987 0.933244664 1.025365503 0.592935872 0.887606878 1 13.4557662 -3.942482921 1.614039378 1.073217668 1.80E-10 0.637479965 0.109098295 1.183234714 1.492449695 0.014549648 2.549962926 0.000114161 3.942482921 -1.073217668 DLNHVCVISETGK(ac)AK ddPTM_HeLa_Curcumin_4h_R1 2 DLNHVCVISETGKAK 15 1 P00492 P00492 HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 0 1 ; DLNHVCVISETGK(1)AK;DLNHVCVISETGK(1)AK 192.4 7.08E-12 10313500 5126.1 4815.2 4680.6 4796.8 5017.4 7849.9 6116.8 6344.7 5777.3 4523.3 FALSE TRUE FALSE 4720.363776 5231.404432 4854.067153 4776.952113 4957.570782 6221.742253 6288.420945 8279.169823 5143.544644 4680.484338 1.008520366 1.117705787 1.037086507 1.020610639 1.059200378 1.329294535 1.343540645 1.768870319 1.098934271 1 12.19244211 -1.000000052 0.533536457 1.005589169 31.90311054 0.927814264 0.06176322 15.40601278 0.135034442 0.009762981 544.5322944 0.099999988 1.000000052 30.89752137 DLPDEVRER ddPTM_HeLa_Curcumin_4h_R1 2 DLPDEVRER 9 1 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5;Q5H9R7-3;H0YDW1 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 0 0 ; ; 111.06 0.0040143 0 5865.8 4313.2 4566.3 4872.4 3604.9 5709.2 3957.6 3910.7 6555.9 5794.6 FALSE FALSE TRUE 5401.51574 4686.013789 4735.531095 4852.2393 3561.913922 4525.047564 4068.639605 5103.054427 5836.734172 5995.961919 0.900858914 0.781528277 0.78978672 0.809251187 0.594052125 0.754682506 0.678563283 0.851081861 0.97344417 1 12.54977551 -7.360236653 0.720573705 0.98107596 0.723225134 0.677610581 0.067382375 0.224237456 0.246600403 0.017785819 0.019818214 4.36E-08 7.360236653 -0.257850826 DLPEHAVLK ddPTM_HeLa_Curcumin_4h_R1 3 DLPEHAVLK 9 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PRZ7;A0A1W2PQD4;A0A1W2PQ74 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 0 ;; ;; 113.62 0.0063702 21913400 23373.6 18606.2 19400.7 19988.6 20897.8 25916.4 20453.3 18755.5 24763.6 21697.3 FALSE FALSE TRUE 21523.5549 20214.43702 20119.70701 19905.89247 20648.60738 20541.0465 21027.16455 24473.96561 22047.09504 22451.27956 0.958678317 0.90036904 0.896149681 0.886626191 0.919707375 0.914916517 0.936568648 1.090092239 0.981997261 1 14.45451005 -8.007150333 1.283626535 0.98999304 0.931343436 0.126273832 0.055229218 0.498926437 1.708310719 0.013538584 0.011375583 9.84E-09 8.007150333 -0.058649604 DLPEHAVLK(ac)MK ddPTM_HeLa_Curcumin_4h_R1 2 DLPEHAVLKMK 11 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PRZ7;A0A1W2PQD4;A0A1W2PQ74 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 1 ; DLPEHAVLK(1)MK;DLPEHAVLK(1)MK 102.52 0.010022 5904600 5996.3 5370.6 5748.8 5984.1 5481.6 7768.3 6554.9 5592.6 7519.4 6097 FALSE TRUE FALSE 5521.686528 5834.810733 5961.855585 5959.33938 5416.2355 6157.067013 6738.812852 7297.757995 6694.540633 6308.870296 0.875225875 0.924858249 0.944995745 0.944596909 0.858511151 0.97593812 1.068148898 1.156745606 1.061131442 1 12.62316598 -4.638290193 2.253934768 0.933971882 1.152483605 0.602847392 0.055391066 0.153298485 1.393484069 0.00736843 0.048504563 2.30E-05 4.638290193 0.218511723 DLPEWEPR ddPTM_HeLa_Curcumin_4h_R1 1 DLPEWEPR 8 0 O94964-2;H0YDM2;O94964;X6R3R3;O94964-4 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 0 0 112.17 0.0085099 10994000 5941.4 5177.7 5495.5 5479.8 5372 5263.9 5109.8 4464.5 5634.8 5592.1 FALSE FALSE TRUE 5471.131921 5625.237317 5699.168064 5457.12604 5307.942409 4172.107804 5253.167236 5825.705498 5016.676538 5786.425059 0.945511584 0.972143812 0.984920397 0.943091111 0.917309454 0.721016476 0.907843303 1.006788378 0.866973388 1 12.49845659 -5.74437228 3.149167749 0.973356579 0.8744361 0.123867207 0.074987314 0.23205055 4.752133859 0.009997816 0.020419921 1.80E-06 5.74437228 -0.098920479 DLPHSVIDNDNYLNFSSLS(ph)SGALPYK ddPTM_HeLa_Curcumin_4h_R1 1 DLPHSVIDNDNYLNFSSLSSGALPYK 26 0 G5E9V3;E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;E9PDY7;A0A1W2PQ63 G5E9V3 PHLDB2 Pleckstrin homology-like domain family B member 2 1 0 DLPHSVIDNDNY(0.018)LNFS(0.221)S(0.221)LS(0.405)S(0.132)GALPY(0.004)K 71.903 0.00022964 8390800 540.81 495.1 407.99 434.71 621.47 722.89 761.26 217.69 565.32 423.58 TRUE FALSE FALSE 498.0043178 537.8942379 423.1104683 432.9112852 614.0593761 572.9544654 782.6189068 284.0626789 503.3058104 438.2993735 1.136219552 1.227230223 0.96534582 0.987706831 1.401004458 1.30722173 1.785580711 0.648101951 1.148315149 1 8.775772806 -5.761384788 25 1.066362008 1.322752086 0.117304138 0.270923911 1.834618222 839165.9612 0.035682974 0.067862728 1.73E-06 5.761384788 0.256390078 NITSSS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 2 NITSSSPER 9 0 A6NF31;O75665-3;O75665 A6NF31 OFD1 Oral-facial-digital syndrome 1 protein 1 0 NIT(0.045)S(0.02)S(0.086)S(0.848)PER;NIT(0.01)S(0.004)S(0.013)S(0.973)PER ; 116.84 0.0070544 230950000 14674.1 13220.9 14138.2 12914.7 13724.3 12445.9 5364 2301.6 13498.7 11727.5 TRUE FALSE FALSE 13512.6295 14363.65568 14662.17413 12861.26239 13560.64669 9864.480046 5514.499404 3003.347245 12017.92638 12135.02975 1.113522569 1.183652284 1.208252013 1.059845971 1.117479476 0.812892943 0.454428173 0.247494016 0.990349973 1 13.56689003 -4.795845098 1.851547891 1.081864783 0.246873047 0.94760559 0.070195135 0.067926396 0.421061189 0.011610663 0.068352996 1.60E-05 4.795845098 -0.834991736 down DLPS(ph)PDSR ddPTM_HeLa_Curcumin_4h_R1 1 DLPSPDSR 8 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 0 DLPS(0.999)PDS(0.001)R 120.45 0.0081333 68020000 6327.1 5238.9 5538.3 5442.3 5937.2 6646.8 7251.5 6255.8 5681.2 5221 TRUE FALSE FALSE 5826.303359 5691.727172 5743.55427 5419.781205 5866.402768 5268.178755 7454.957574 8163.164622 5057.986574 5402.429361 1.078459887 1.053549578 1.063142873 1.003211859 1.085882364 0.975149956 1.379926895 1.511017373 0.936242982 1 12.39939259 -4.657408372 4.314817641 1.038641199 1.481157502 0.920247352 0.049922314 0.031916477 1.024249093 0.005730033 0.023722581 2.20E-05 4.657408372 0.442516303 DLPTIPGVTSPSSDEPPMEASQSHLRNS(ph)PEDKR ddPTM_HeLa_Curcumin_4h_R1 1 DLPTIPGVTSPSSDEPPMEASQSHLRNSPEDKR 33 2 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 0 DLPTIPGVT(0.02)S(0.005)PS(0.019)S(0.019)DEPPMEAS(0.305)QS(0.267)HLRNS(0.364)PEDKR 41.89 0.010308 19224000 1611.2 1042.9 1083.1 1003.6 1865.5 2049.5 1466.2 1480.1 1483.6 1178.1 TRUE FALSE FALSE 1483.67182 1133.043629 1123.240639 999.4473691 1843.255131 1624.410597 1507.337626 1931.375676 1320.852792 1219.038887 1.217083257 0.929456509 0.921414936 0.819865042 1.512056055 1.332533863 1.236496753 1.584342958 1.083519817 1 10.25152843 -5.748228346 24.99998751 1.057720397 1.397522848 0.668027721 0.14112852 145.1306217 274637.2529 0.023119992 0.046020916 1.79E-06 5.748228346 0.339802451 DLQELGDSDKYFIEDGR ddPTM_HeLa_Curcumin_4h_R1 2 DLQELGDSDKYFIEDGR 17 1 P32004-3;P32004-2;P32004;H0Y5C3 P32004-3 L1CAM Neural cell adhesion molecule L1 0 0 ; ; 213.02 2.02E-15 9310500 2840.2 2230.88 2174.79 2878.5 2522.28 4109.4 2323.11 2120.67 3562.5 2267.82 FALSE FALSE TRUE 2615.395173 2423.707327 2255.389631 2866.58953 2492.203458 3257.064118 2388.290214 2767.252521 3171.702663 2346.626576 1.114534029 1.032847472 0.961119956 1.221578908 1.062036663 1.387977171 1.017754695 1.179247073 1.35160093 1 11.19637257 -6.251206169 24.90085007 1.047190051 1.170752892 0.03318359 0.138604245 690.3143749 1679766.521 0.014603816 0.024040072 5.61E-07 6.251206169 0.123562841 DLQEQDADAGS(ph)ER ddPTM_HeLa_Curcumin_4h_R1 2 DLQEQDADAGSER 13 0 A0A087WW12;A0A087WZ11;Q6P158-3;Q6P158-2;Q6P158 A0A087WW12 DHX57 Putative ATP-dependent RNA helicase DHX57 1 0 DLQEQDADAGS(1)ER;DLQEQDADAGS(1)ER ; 271.41 3.69E-47 232280000 6430.4 5307.6 6149.6 5365.7 6090.6 7111.8 5349.3 3015 4984.9 5093.4 TRUE FALSE FALSE 5921.427055 5766.365294 6377.509586 5343.498155 6017.973573 5636.732513 5499.386961 3934.259621 4438.068942 5270.395271 1.123526178 1.094104901 1.210062862 1.013870475 1.141844826 1.069508495 1.043448675 0.746482838 0.84207516 1 12.36369545 -4.254346394 3.550102328 1.075963034 0.705040857 0.493672225 0.094497998 0.133190951 2.914486788 0.009360199 0.1325328 5.57E-05 4.254346394 -0.370922177 DLQGRDEQSEEK ddPTM_HeLa_Curcumin_4h_R1 3 DLQGRDEQSEEK 12 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ;; ;; 140.45 5.91E-05 79835300 7084.3 5428.4 6073 7020.1 5157.5 7642.8 5973.5 5269.1 7962.8 6977.1 FALSE FALSE TRUE 6523.57018 5897.606708 6298.070722 6991.052686 5096.000181 6057.597128 6141.100333 6875.624334 7089.300762 7219.553706 0.903597431 0.816893529 0.872362888 0.968349703 0.705860831 0.839054237 0.850620493 0.952361408 0.981958311 1 12.81769394 -8.34228201 0.603794454 0.998503458 0.852230336 0.352565364 0.069436594 0.573220071 0.450696507 0.038184165 0.018397445 4.55E-09 8.34228201 -0.146273121 RGTGQSDDS(ph)DIWDDTALIK ddPTM_HeLa_Curcumin_4h_R1 1 RGTGQSDDSDIWDDTALIK 19 1 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 0 RGT(0.003)GQS(0.125)DDS(0.873)DIWDDTALIK 103.51 0.00034468 66904000 7379.7 4943.1 5847.1 5315 5556.9 5593.3 2137.8 1111.5 6944.6 4958.2 TRUE FALSE FALSE 6795.588958 5370.359538 6063.79867 5293.007938 5490.637597 4433.186531 2197.780914 1450.391233 6182.794755 5130.497081 1.324547866 1.046752284 1.181912507 1.03167546 1.070196028 0.864085187 0.428375824 0.282699943 1.205106378 1 12.3248829 -4.795378694 1.358068642 1.14394937 0.195729909 0.919620725 0.090389881 0.152630317 0.43712839 0.018683919 0.151728477 1.60E-05 4.795378694 -0.94821946 down VTNDIS(ph)PES(ph)SPGVGR ddPTM_HeLa_Curcumin_4h_R1 1 VTNDISPESSPGVGR 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 2 0 VT(0.004)NDIS(0.999)PES(0.833)S(0.164)PGVGR 106.82 0.0061236 27297000 4651.6 4403.4 4291.1 4173.5 4072.9 4204.5 1239.3 746.71 5067.2 5140.6 TRUE FALSE FALSE 4283.420952 4784.010275 4450.131941 4156.231163 4024.333328 3332.439306 1274.071423 974.3784416 4511.340838 5319.235467 0.805270039 0.899379301 0.836611195 0.781358748 0.756562358 0.626488398 0.239521531 0.183180167 0.84811828 1 12.37700319 -4.79258194 0.871176314 0.901652999 1.05E-21 0.938210087 0.064617553 0.238655777 0.213474257 0.013347094 0.171686923 1.61E-05 4.79258194 -0.901652999 down DLRPVDNR ddPTM_HeLa_Curcumin_4h_R1 1 DLRPVDNR 8 1 P42285 P42285 SKIV2L2 Superkiller viralicidic activity 2-like 2 0 0 90.37 0.017946 3384500 1478.2 1222.3 1454.8 1358.8 1115.2 1225.1 1158.7 1149.6 1446.1 1405 FALSE FALSE TRUE 1361.19891 1327.950166 1508.716168 1353.177646 1101.901968 971.0004503 1191.210004 1500.107748 1287.466448 1453.823645 0.936288878 0.913419017 1.037757346 0.930771521 0.757933723 0.667894248 0.819363481 1.031836119 0.885572643 1 10.50563656 -5.892667375 5.50427686 0.969221299 0.80931422 0.310665144 0.094493608 0.160367404 7.254802112 0.013550492 0.024881209 1.28E-06 5.892667375 -0.15990708 DLRS(ph)PLTATPTFVTDSESTR ddPTM_HeLa_Curcumin_4h_R1 1 DLRSPLTATPTFVTDSESTR 20 1 A0A087WUK4;P13056-2;P13056-3;P13056 A0A087WUK4 NR2C1 Nuclear receptor subfamily 2 group C member 1 1 0 DLRS(0.939)PLT(0.039)AT(0.022)PTFVTDSESTR 63.936 0.0049493 6534600 879.57 682.23 806.06 832.64 579.2 918.74 680.52 1108.6 967.08 762.09 TRUE FALSE FALSE 809.9511064 741.1989212 835.9332927 829.1947563 572.2934183 728.1829677 699.6135597 1446.607037 860.9937435 788.5725708 1.027110423 0.939924807 1.060058799 1.051513566 0.725733356 0.923419092 0.887189823 1.834462788 1.091838311 1 9.623099719 -4.257523835 24.93144832 0.982535922 1.83446313 0.864908789 0.10264287 95.22853967 606323.0614 0.013787496 0.139497509 5.53E-05 4.257523835 0.851927209 DLS(ph)LEEIQK ddPTM_HeLa_Curcumin_4h_R1 3 DLSLEEIQK 9 0 P16949;P16949-2;A2A2D0;E5RGX5;Q93045;Q93045-2 P16949;E5RGX5 STMN1;STMN2 Stathmin;Stathmin-2 1 0 DLS(1)LEEIQK;DLS(1)LEEIQK;DLS(1)LEEIQK ;; 133.89 0.0033071 29910900 6447.6 5168 5366.3 5903.9 5604.1 7876.9 6700 5329.2 6320.1 5840.7 TRUE FALSE FALSE 5937.265657 5614.698892 5565.179799 5879.471226 5537.274768 6243.142149 6887.983968 6954.048547 5626.800842 6043.66389 0.982395078 0.92902236 0.920828805 0.972832264 0.916211568 1.03300618 1.139703348 1.150634561 0.93102478 1 12.56120771 -4.864354736 3.312541053 0.97533386 1.148691497 0.828748442 0.03396647 0.078454174 1.671117869 0.005113351 0.018508026 1.37E-05 4.864354736 0.173357637 DLS(ph)MSEEDQMMR ddPTM_HeLa_Curcumin_4h_R1 2 DLSMSEEDQMMR 12 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 DLS(0.868)MS(0.132)EEDQMMR;DLS(0.797)MS(0.203)EEDQMMR ; 228.17 6.62E-19 14498400 3500.81 2806.16 2785.93 2878.32 3218.54 4067.45 2605.54 8149.8 3506.27 3252.42 TRUE FALSE FALSE 3223.717194 3048.711966 2889.179017 2866.410274 3180.161013 3223.81502 2678.64444 10634.6365 3121.640953 3365.441353 0.957888389 0.905887712 0.858484434 0.851718979 0.944946198 0.957917456 0.795926644 3.159953001 0.927557674 1 11.71658 -4.259095875 24.99975215 0.945093153 3.159953772 0.990477427 0.066074311 15.5106673 165452.0975 0.010207069 0.091889394 5.51E-05 4.259095875 2.21486062 DLS(ph)PEPAPDEGPRR ddPTM_HeLa_Curcumin_4h_R1 2 DLSPEPAPDEGPRR 14 1 Q8TBE0-3;Q8TBE0-2;Q8TBE0 Q8TBE0-3 BAHD1 Bromo adjacent homology domain-containing 1 protein 1 0 DLS(1)PEPAPDEGPRR;DLS(1)PEPAPDEGPRR ; 92.952 0.0039324 50136000 4260.3 4499.1 4510.5 4420.8 4428.4 5113.5 3069.3 1893.39 4558.6 3913.4 TRUE FALSE FALSE 3923.09276 4887.982156 4677.663098 4402.507901 4375.594222 4052.902459 3155.416297 2470.675895 4058.532985 4049.390359 0.968810713 1.207090876 1.155152426 1.087202643 1.08055629 1.000867316 0.779232432 0.610135274 1.002257778 1 11.98348901 -4.594379161 2.38084893 1.029323126 0.612243069 0.788992053 0.077081872 0.143306915 1.442496915 0.013315804 0.091334921 2.54E-05 4.594379161 -0.417080057 DLS(ph)PTLIDNSAAK ddPTM_HeLa_Curcumin_4h_R1 2 DLSPTLIDNSAAK 13 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 0 DLS(1)PTLIDNSAAK;DLS(1)PTLIDNSAAK ; 263.9 1.39E-46 106827000 10759.4 9569.3 9012.8 9272.2 9440.4 9811.3 7026.6 6224.4 9004.5 8360.9 TRUE FALSE FALSE 9907.782137 10396.42765 9346.822296 9233.834093 9327.829396 7776.325784 7223.747485 8122.190906 8016.728878 8651.440653 1.145217604 1.201699008 1.080377555 1.06731751 1.078182209 0.898847498 0.834976251 0.938825247 0.926635135 1 13.07872468 -5.248351602 4.993180223 1.081963908 0.882831254 0.552059036 0.074077254 0.094704165 7.160860714 0.010242348 0.025644453 5.64E-06 5.248351602 -0.199132654 RS(ph)SSSGDQSSDSLNS(ph)PTLLAL ddPTM_HeLa_Curcumin_4h_R1 1 RSSSSGDQSSDSLNSPTLLAL 21 1 P15408;P15408-3;P15408-2 P15408 FOSL2 Fos-related antigen 2 2 0 RS(0.425)S(0.345)S(0.03)S(0.018)GDQS(0.081)S(0.099)DS(0.002)LNS(0.991)PT(0.009)LLAL 102.66 0.00013225 13774000 863.93 663.82 771.12 897.92 773.99 1349.4 2004.8 2890.8 1118.9 1102.6 TRUE FALSE FALSE 795.5490289 721.1976429 799.6983855 894.204645 764.7606748 1069.519229 2061.049292 3772.191612 996.1594693 1140.915268 0.697290194 0.632122002 0.700927061 0.783760784 0.670304532 0.937422137 1.806487607 3.306285505 0.873123095 1 10.15597594 -4.34235025 1.790844572 0.805029624 3.890908808 0.980076321 0.111706676 0.094250377 0.341719602 0.022145458 0.462997617 4.55E-05 4.34235025 3.085879184 up DLS(ph)TSPKPS(ph)PIPS(ph)PVLGR ddPTM_HeLa_Curcumin_4h_R1 1 DLSTSPKPSPIPSPVLGR 18 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 3 0 DLS(0.346)T(0.346)S(0.346)PKPS(0.978)PIPS(0.984)PVLGR 72.532 0.008104 17409000 4297 4146.2 4057.1 3942.6 4198.8 4039.3 3431.2 2651.4 4239.3 3942.3 TRUE FALSE FALSE 3956.887916 4504.579053 4207.459695 3926.286566 4148.732052 3201.503648 3527.470237 3459.799654 3774.259396 4079.294632 0.969993166 1.104254402 1.031418438 0.962491538 1.017021919 0.784817949 0.864725536 0.848136741 0.925223534 1 11.994104 -5.268401292 24.98062291 0.998146161 0.83577662 0.716267558 0.048677398 197.2823622 707886.1989 0.006413818 0.014635085 5.39E-06 5.268401292 -0.162369541 DLSELGSVR ddPTM_HeLa_Curcumin_4h_R1 1 DLSELGSVR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 110.12 0.0035824 4291000 2664.4 3374.2 2613 2639.5 2620.4 1629.4 1399.7 1667.7 2561 2865.9 FALSE FALSE TRUE 2453.509929 3665.850813 2709.840079 2628.578448 2589.153441 1291.444073 1438.971815 2176.174053 2280.064707 2965.489812 0.827354024 1.236170429 0.913791734 0.886389303 0.873094701 0.435490983 0.48523917 0.733832922 0.768866141 1 11.5340547 -5.370768146 4.840273706 0.938397022 0.546498949 0.614593851 0.137628136 0.105332399 3.821295712 0.019019238 0.043641299 4.26E-06 5.370768146 -0.391898073 DLSHIGDAVVISCAK ddPTM_HeLa_Curcumin_4h_R1 1 DLSHIGDAVVISCAK 15 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 0 137.09 0.0004483 2432300 5022.7 3642.8 4298.3 4137.3 4039.9 6890.5 4556 4979.2 5594.6 4802.3 FALSE FALSE TRUE 4625.147995 3957.6674 4457.598779 4120.180949 3991.726831 5461.332628 4683.829098 6497.335159 4980.886377 4969.179568 0.930766927 0.796442822 0.897049245 0.829147124 0.803296958 1.09904111 0.942575939 1.30752674 1.002355884 1 12.27879196 DLSLEEIQK ddPTM_HeLa_Curcumin_4h_R1 2 DLSLEEIQK 9 0 P16949;P16949-2;A2A2D0;E5RGX5;Q93045;Q93045-2 P16949;E5RGX5 STMN1;STMN2 Stathmin;Stathmin-2 0 0 ; ; 166.16 1.35E-11 12482200 5039.9 4303.5 4954.4 5048.3 4676.1 6271.4 5049.3 4922.6 5694.3 4774.6 FALSE FALSE TRUE 4640.986597 4675.475364 5138.014422 5027.411472 4620.340562 4970.640947 5190.969769 6423.478079 5069.649536 4940.516995 0.939372661 0.946353462 1.039975053 1.017588135 0.935193739 1.006097328 1.050693637 1.300163138 1.026137455 1 12.2704463 -4.125764992 1.710731348 0.975661529 1.499776659 0.864518388 0.036661555 0.339528055 0.732223658 0.005317216 0.322314944 7.49E-05 4.125764992 0.52411513 DLSMS(ph)EEDQMMR ddPTM_HeLa_Curcumin_4h_R1 1 DLSMSEEDQMMR 12 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 DLS(0.297)MS(0.703)EEDQMMR 125.84 0.0029683 9403500 994.64 819.55 686.18 794.48 814.04 1138.8 620 2338.9 1089.4 803.89 TRUE FALSE FALSE 915.9131945 890.3882502 711.6104344 791.1926523 804.3331047 902.6000431 637.3955314 3052.019843 969.8955455 831.8251177 1.101088648 1.070403179 0.855480821 0.951152635 0.966949768 1.0850839 0.766261463 3.6690643 1.165984923 1 9.700136439 -4.258189332 24.99999959 1.013911006 3.669065281 0.979917155 0.114783095 26.76081238 205839.5539 0.014514173 0.13949214 5.52E-05 4.258189332 2.655154275 DLSQESSSTAPGSEVT(ph)IKQEPVSPK ddPTM_HeLa_Curcumin_4h_R1 1 DLSQESSSTAPGSEVTIKQEPVSPK 25 1 E7EWM1;Q15596 E7EWM1 NCOA2 Nuclear receptor coactivator 2 1 0 DLSQESSSTAPGS(0.012)EVT(0.902)IKQEPVS(0.086)PK 79.993 0.00012931 8905100 1748.4 1264.7 1284.8 1136 1029.6 1565.2 848.66 716.72 2457.2 1728.6 TRUE FALSE FALSE 1610.012295 1374.015033 1332.415818 1131.299533 1017.322692 1240.559877 872.4711155 935.2446286 2187.651308 1788.668721 0.900117655 0.768177481 0.744920399 0.632481308 0.568759704 0.693566037 0.487776806 0.522871909 1.223061197 1 10.8046705 -6.681259713 0.511398554 0.991597671 0.513352855 0.833214164 0.089399716 0.155764231 0.08679065 0.015121515 0.02954261 2.08E-07 6.681259713 -0.478244816 DLSQESSSTAPGSEVTIKQEPVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 DLSQESSSTAPGSEVTIKQEPVSPK 25 1 E7EWM1;Q15596 E7EWM1 NCOA2 Nuclear receptor coactivator 2 1 0 DLSQESSSTAPGSEVT(0.031)IKQEPVS(0.969)PK;DLSQESSSTAPGS(0.002)EVT(0.045)IKQEPVS(0.953)PK;DLSQESSSTAPGS(0.01)EVT(0.003)IKQEPVS(0.987)PK ;; 132.7 4.08E-08 39178500 5170 3818.24 4299.34 4755.11 3457.13 4964.34 3974.11 2429.5 6433.1 5348.7 TRUE FALSE FALSE 4760.789045 4148.271652 4458.677322 4735.434615 3415.905983 3934.679924 4085.612831 3170.243366 5727.405025 5534.566927 0.860191792 0.749520551 0.805605458 0.855610688 0.61719481 0.71092824 0.738199192 0.572807847 1.034842491 1 12.43425472 -4.100056196 0.086591382 1.277635618 3.71E-09 0.814345864 0.061076539 21.71411509 0.289720565 1.096219322 3.85463351 7.94E-05 4.100056196 -1.277635614 DLSSS(ph)PPGPYGQEMYAFR ddPTM_HeLa_Curcumin_4h_R1 3 DLSSSPPGPYGQEMYAFR 18 0 O43741;O43741-2 O43741 PRKAB2 5-AMP-activated protein kinase subunit beta-2 1 0 DLS(0.031)S(0.153)S(0.807)PPGPY(0.007)GQEMY(0.001)AFR;DLS(0.004)S(0.024)S(0.663)PPGPY(0.308)GQEMY(0.002)AFR;DLS(0.021)S(0.129)S(0.849)PPGPY(0.001)GQEMYAFR ;; 112.24 0.00074041 123745000 7861.9 6565.5 6204.04 6809.6 6743.8 7528.5 5412.35 4226.11 7076.2 6735.7 TRUE FALSE FALSE 7239.622319 7132.992565 6433.96718 6781.42368 6663.38459 5967.004236 5564.205974 5514.631484 6299.958564 6969.765074 1.03871827 1.023419368 0.923125401 0.972977368 0.956041491 0.856127025 0.798334795 0.791222003 0.903898266 1 12.76689431 -5.099426844 0.698691838 1.017371696 0.736311637 0.706999416 0.045488875 0.289614625 0.180784865 0.005505798 0.051581834 7.95E-06 5.099426844 -0.281060058 DLST(ph)PGLEK ddPTM_HeLa_Curcumin_4h_R1 1 DLSTPGLEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 DLS(0.057)T(0.943)PGLEK 163.38 0.0013303 35902000 8742 8183.5 8667.3 8368.5 8335.8 10414 9728.6 2672.6 8752.2 7458.6 TRUE FALSE FALSE 8050.061475 8890.845275 8988.517763 8333.873364 8236.401029 8254.01901 10001.55833 3487.463437 7792.105557 7717.785795 1.04305324 1.151994304 1.16464981 1.079826985 1.067197412 1.069480189 1.29591033 0.451873572 1.009629674 1 12.91397129 -4.247517688 24.99967801 1.063254733 0.451873166 0.820352206 0.089385785 824.3709636 1480328.434 0.013001417 0.360325873 5.66E-05 4.247517688 -0.611381567 DLST(ph)S(ph)PKPSPIPS(ph)PVLGR ddPTM_HeLa_Curcumin_4h_R1 1 DLSTSPKPSPIPSPVLGR 18 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 3 0 DLS(0.477)T(0.673)S(0.654)PKPS(0.205)PIPS(0.991)PVLGR 129.43 7.99E-05 0 1610 1407 1511.2 1251.4 1608 1711 1420.3 1062.1 1956.3 1864.5 TRUE FALSE FALSE 1482.566801 1528.614811 1567.206401 1246.222038 1588.82565 1356.119313 1460.149795 1385.929401 1741.698784 1929.291236 0.768451529 0.792319367 0.812322355 0.645948116 0.823528154 0.702910627 0.756832234 0.718361943 0.902766131 1 10.91385523 -9.587100581 0.367234787 1.122130799 0.731281975 0.653501779 0.056894828 1.01609453 0.149264727 0.162952412 0.017016499 2.59E-10 9.587100581 -0.390848825 DLTDYLMK ddPTM_HeLa_Curcumin_4h_R1 5 DLTDYLMK 8 0 P60709;A0A2R8Y793;P63267-2;A0A2R8YEA7;Q562R1;P63261;I3L3I0;I3L1U9;I3L4N8;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;ACTG2;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 0 0 ;;;; ;;;; 141.47 0.00059606 168333600 21663.8 16876.2 19671 18098.7 17892.6 20002.9 19340.3 18349.6 16978.4 14441.6 FALSE FALSE TRUE 19949.08737 18334.90353 20400.02456 18023.81237 17679.24243 15854.07306 19882.93677 23944.30857 15115.912 14943.44453 1.334972492 1.226952962 1.365148747 1.206135061 1.183076793 1.060938329 1.330545761 1.602328602 1.011541347 1 13.86722511 -9.333166492 0.897391195 0.987827658 1.280805566 0.409628677 0.135274841 0.567372608 0.763201355 0.115388177 0.025840426 4.64E-10 9.333166492 0.292977908 DLTEYLSR ddPTM_HeLa_Curcumin_4h_R1 2 DLTEYLSR 8 0 O14979-3;O14979-2;A0A087WUK2;O14979 O14979-3 HNRNPDL Heterogeneous nuclear ribonucleoprotein D-like 0 0 ; ; 115.49 0.0034503 7042400 4179.8 3465.8 3884 3734.3 4009.4 4919.7 3465.8 3849.6 4498.6 4066.7 FALSE FALSE TRUE 3848.964419 3765.368309 4027.944457 3718.848456 3961.590524 3899.298764 3563.04102 5023.325319 4005.114835 4208.017522 0.914674048 0.894808134 0.957207149 0.883753082 0.941438695 0.926635581 0.846726755 1.193751046 0.951781882 1 12.038925 -4.247763941 24.62248196 0.940328062 1.193751254 0.76981869 0.043425436 845.9440779 1523081.978 0.007031067 0.18771034 5.65E-05 4.247763941 0.253423192 DLTNNNIPHLLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 DLTNNNIPHLLSPK 14 0 A0A1B0GTX4;A0A096LNR9;A0A1B0GUM4;A0A669KBC2;O76039;O76039-1 A0A1B0GTX4 CDKL5 Cyclin-dependent kinase-like 5 1 0 DLTNNNIPHLLS(1)PK;DLTNNNIPHLLS(1)PK ; 181.81 0.00010551 27639000 3873 2837.1 3663 3561.2 3675.4 4858.8 3859.5 3915 3835.5 3524.9 TRUE FALSE FALSE 3566.447963 3082.326282 3798.754002 3546.464698 3631.573255 3851.03011 3967.787183 5108.665478 3414.755246 3647.390013 0.977808227 0.845077239 1.041499261 0.972329443 0.995663541 1.055831731 1.08784286 1.400635923 0.93621884 1 11.83264876 DLTQMADELRR ddPTM_HeLa_Curcumin_4h_R1 1 DLTQMADELRR 11 1 P41227;P41227-2;C9JN83 P41227 NAA10 N-alpha-acetyltransferase 10 0 0 88.134 0.019095 18398000 1734.8 1541.4 1747.8 1762 2079.7 3290.9 1833.9 1581.5 2336 1913.1 FALSE FALSE TRUE 1597.488749 1674.631748 1812.575006 1754.709311 2054.900936 2608.330244 1885.354298 2063.69207 2079.746644 1979.580083 0.806983644 0.845953019 0.91563611 0.886404812 1.038048904 1.317617947 0.952401125 1.042489813 1.050599904 1 10.95097872 -5.649329144 4.642815533 0.900809523 1.101661044 0.373761697 0.108475158 0.159304583 5.787788803 0.01606879 0.032772153 2.24E-06 5.649329144 0.200851522 VVELRPPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 VVELRPPSR 9 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 0 VVELRPPS(1)R 72.289 0.01858 9913700 2559.2 2136.8 2504.2 2238.8 2119.9 2129.4 1717.6 901.78 2532.2 2295.1 TRUE FALSE FALSE 2356.63662 2321.495471 2597.007855 2229.536439 2094.621577 1687.738437 1765.791233 1176.728571 2254.423995 2374.854554 0.992328821 0.977531641 1.093543961 0.938809678 0.881999941 0.710670232 0.74353658 0.495495006 0.949289291 1 11.21362344 -4.786641193 0.7986219 1.003324873 0.441074512 0.891665019 0.055614957 0.277085293 0.197520322 0.008381511 0.11720683 1.63E-05 4.786641193 -0.562250362 down DLTSLETTSEMEAGS(ph)PENKK ddPTM_HeLa_Curcumin_4h_R1 1 DLTSLETTSEMEAGSPENKK 20 1 Q5VYS8-4;Q5VYS8;Q5VYS8-5;Q5VYS8-3;Q5VYS8-2;Q5VYS8-6 Q5VYS8-4 ZCCHC6 Terminal uridylyltransferase 7 1 0 DLTSLETT(0.001)S(0.004)EMEAGS(0.995)PENKK 73.11 0.003296 23027000 2030 1376.8 1534.7 1844.1 1575.2 1943.8 1779.9 549.84 2041.3 1833.5 TRUE FALSE FALSE 1869.323358 1495.804457 1591.577332 1836.469603 1556.416769 1540.633969 1829.839204 717.4836848 1817.374497 1897.213989 0.985299165 0.788421584 0.838902381 0.967982322 0.820369646 0.812050711 0.964487514 0.378177522 0.957917509 1 10.8896667 -4.260066183 24.85457565 0.942329239 0.378177324 0.763888183 0.085320409 42.1707368 763192.2337 0.013877924 0.11630873 5.49E-05 4.260066183 -0.564151916 DLVLPTQALPAS(ph)PALK ddPTM_HeLa_Curcumin_4h_R1 2 DLVLPTQALPASPALK 16 0 J3KSZ6;U3KQ35;H3BR06;Q15554 J3KSZ6 TERF2 Telomeric repeat-binding factor 2 1 0 DLVLPT(0.003)QALPAS(0.997)PALK;DLVLPT(0.027)QALPAS(0.973)PALK ; 137.52 0.00041306 403600000 21999 16944.6 19473.1 20953.5 19499.1 22866.5 18607.8 9608.9 20308.6 17257.5 TRUE FALSE FALSE 20257.75594 18409.21572 20194.79022 20866.79997 19266.58597 18123.73014 19129.88479 12538.60938 18080.79739 17857.19684 1.134430903 1.030912964 1.130904833 1.168537266 1.078925553 1.01492582 1.07127031 0.702160002 1.012521593 1 14.12421801 -4.261356512 9.423688911 1.072215732 0.700885043 0.801394802 0.055140415 0.029374378 63.31200094 0.008778705 0.068471413 5.48E-05 4.261356512 -0.371330689 DLVQPDKPAS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 DLVQPDKPASPK 12 1 Q6PJT7;Q6PJT7-5;H0YJA2;Q6PJT7-9;Q6PJT7-2;G3V411;G3V4R5 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 1 0 DLVQPDKPAS(1)PK 93.181 0.0057326 465540000 5962.1 5096.7 5341.3 4944.3 5427.4 5694.7 5539.5 4453.4 5665 5178.1 TRUE FALSE FALSE 5490.193494 5537.236038 5539.253277 4923.841797 5362.6818 4513.555028 5694.923461 5811.221159 5043.563673 5358.03859 1.024664791 1.033444598 1.033821087 0.918963482 1.000866588 0.842389421 1.062874663 1.084579938 0.941307829 1 12.38748926 DLYANTVLS(ph)GGTTMYPGIADR ddPTM_HeLa_Curcumin_4h_R1 1 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 1 0 DLYANT(0.048)VLS(0.432)GGT(0.316)T(0.151)MY(0.053)PGIADR 113.23 2.62E-05 7950300 2836.3 2568 3024.2 2584.5 2386 4091.5 2794.4 2863.4 3093.5 2170.4 TRUE FALSE FALSE 2611.803862 2789.966477 3136.279512 2573.806024 2357.548508 3242.876779 2872.803343 3736.437479 2754.15079 2245.821238 1.162961601 1.24229232 1.396495615 1.146042249 1.04974896 1.443960331 1.279177209 1.663728802 1.226344618 1 11.13302738 -1 0.169299571 0.987578662 3.087810829 0.409966852 0.144008664 32.97995942 0.345540842 0.199400428 17.61798517 0.1 1 2.100232167 DLYANTVLSGGT(ph)TMYPGIADR ddPTM_HeLa_Curcumin_4h_R1 1 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 1 0 DLYANTVLS(0.155)GGT(0.547)T(0.255)MY(0.043)PGIADR 126.09 0.00041292 8589100 4900.3 4402 4248 4951.4 4779.2 5852.8 4113.6 3932.6 4996.3 4240.9 TRUE FALSE FALSE 4512.436084 4782.489265 4405.434617 4930.912419 4722.211161 4638.863305 4229.016545 5131.631637 4448.21839 4388.270959 1.028294772 1.089834541 1.003911257 1.123657236 1.076098355 1.05710503 0.963709074 1.169397169 1.013660832 1 12.09943689 -7.679321955 0.876272446 1.005616633 1.066575553 0.172476126 0.054425781 0.604244801 0.98148441 0.013479644 0.012575232 2.09E-08 7.679321955 0.06095892 DLYANTVLSGGTTMYPGIADR ddPTM_HeLa_Curcumin_4h_R1 4 DLYANTVLSGGTTMYPGIADR 21 0 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 0 0 ;;; ;;; 233.84 1.05E-28 300074000 5590.45 4725.73 4479.71 4540.08 4875.86 7368.17 5364.33 5615.12 5823.36 4961.83 FALSE FALSE TRUE 5147.959983 5134.201044 4645.731993 4521.294352 4817.718554 5839.928486 5514.838662 7327.144239 5184.551977 5134.253223 1.00266967 0.999989837 0.904850577 0.880613822 0.93834845 1.137444577 1.074126737 1.427110024 1.009796703 1 12.32593874 -3.548665086 1.063062522 0.984053842 2.752931668 0.82950927 0.06123824 2.096424937 0.630096505 0.009640388 6.056516762 0.000282706 3.548665086 1.768877826 DLYDAGVK ddPTM_HeLa_Curcumin_4h_R1 1 DLYDAGVK 8 0 P07355;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YNP5;H0YN28;H0YL33;P07355-2 P07355;P07355-2 ANXA2 Annexin A2;Annexin 0 0 133.55 0.001319 20974000 8967.4 5344.9 8123.5 7600.2 9140.5 11943 9619.7 10901 7387.7 5226.7 FALSE FALSE TRUE 8257.620828 5806.88934 8424.564056 7568.752386 9031.505507 9465.887175 9889.602892 14224.66472 6577.287793 5408.327436 1.526834484 1.073694115 1.557702294 1.399462676 1.669925798 1.750242989 1.828588045 2.630141183 1.216140826 1 12.40096678 -1 0.318291199 1.186468495 13.52499815 0.846284306 0.173599325 16.38474724 0.208999189 0.069871067 119.1020901 0.1 1 12.33852966 up DLYDAGVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 DLYDAGVKR 9 1 P07355;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YNP5;H0YN28;H0YL33;P07355-2 P07355;P07355-2 ANXA2 Annexin A2;Annexin 0 1 DLYDAGVK(1)R 98.033 0.0039992 24712000 4664.2 6737.9 3962.8 4592.6 8867.1 12840 10147 9627.3 15045 4725.8 FALSE TRUE FALSE 4295.023648 7320.294053 4109.664854 4573.597038 8761.365624 10176.83926 10431.69751 12562.61945 13394.60114 4890.021198 0.878324137 1.496986159 0.840418617 0.935291863 1.791682545 2.081144202 2.133262227 2.569031696 2.739170363 1 12.255625 -5.525960024 1.876367017 0.973263776 2.296250729 0.233244134 0.59890083 0.081427788 0.566518405 0.032027144 0.084204754 2.98E-06 5.525960024 1.322986954 DLYDDKDGLR ddPTM_HeLa_Curcumin_4h_R1 1 DLYDDKDGLR 10 1 Q12874 Q12874 SF3A3 Splicing factor 3A subunit 3 0 0 117.81 0.0042648 14801000 5386.8 5300.2 6017.3 5846.7 6857.7 6771.6 5720.8 5864.6 5175.2 4870.4 FALSE FALSE TRUE 4960.429096 5758.325671 6240.306431 5822.507905 6775.926406 5367.093828 5881.310251 7652.689543 4607.493508 5039.646037 0.984281249 1.142605181 1.238243001 1.155340645 1.344524269 1.064974363 1.167008597 1.518497427 0.914249428 1 12.29910669 -7.067255545 2.509349237 0.991777937 1.236947052 0.529000141 0.117769264 0.171489279 2.119966647 0.018759453 0.023842273 8.57E-08 7.067255545 0.245169115 DLYDDKDGLRKEELNAISGPNEFAEFYNR ddPTM_HeLa_Curcumin_4h_R1 1 DLYDDKDGLRKEELNAISGPNEFAEFYNR 29 3 Q12874 Q12874 SF3A3 Splicing factor 3A subunit 3 0 0 53.798 0.0015966 15683000 562.84 436.52 681.18 483.47 522.07 886.68 648.5 577.95 658.46 618.85 FALSE FALSE TRUE 518.2906201 474.2508437 706.42513 481.4695292 515.8446562 702.7725731 666.6951647 754.1642944 586.2285854 640.3549914 0.809380152 0.740606148 1.103177362 0.751879092 0.805560452 1.097473405 1.041133705 1.177728455 0.915474375 1 9.322728099 -5.244584699 23.25277586 0.891695666 1.099014129 0.470301736 0.110968497 266.3963559 367518.8038 0.016838439 0.042765821 5.69E-06 5.244584699 0.207318463 DLYRPLS(ph)SDDLDSVGDSV ddPTM_HeLa_Curcumin_4h_R1 2 DLYRPLSSDDLDSVGDSV 18 1 Q5VZY9 Q5VZY9 DCLK1 1 0 DLYRPLS(0.695)S(0.224)DDLDS(0.082)VGDSV;DLYRPLS(0.474)S(0.474)DDLDS(0.011)VGDS(0.041)V ; 122.97 0.0028528 45537000 3733 3365.7 3294.7 3661 3065.19 3368.8 3026.5 4829.2 3707.7 2949.1 TRUE FALSE FALSE 3437.529111 3656.616111 3416.80448 3645.851752 3028.639611 2670.072906 3111.415445 6301.600849 3300.974586 3051.581005 1.126474803 1.19826939 1.119683362 1.194741921 0.992482128 0.874980183 1.019607685 2.065028206 1.081726023 1 11.57534117 -4.259885425 24.96019491 1.064266616 2.065028544 0.909278657 0.094516275 30.08038008 483114.9022 0.01444741 0.122920816 5.50E-05 4.259885425 1.000761927 DMAECSTPLPEDCS(ph)PTHSPR ddPTM_HeLa_Curcumin_4h_R1 2 DMAECSTPLPEDCSPTHSPR 20 0 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 DMAECSTPLPEDCS(0.671)PT(0.323)HS(0.005)PR;DMAECSTPLPEDCS(0.975)PT(0.023)HS(0.002)PR ; 129.08 3.66E-05 36773000 6007.2 5008.6 5391.5 6104.8 6597.4 7639.5 5322.7 5205.7 6848.7 5373.8 TRUE FALSE FALSE 5531.723781 5441.521066 5591.313733 6079.539955 6518.730314 6054.981585 5472.040637 6792.893966 6097.414745 5560.53915 0.994817882 0.978595945 1.00553446 1.093336418 1.172319831 1.088919873 0.984084545 1.221625059 1.096550996 1 12.44100906 -6.250856407 4.318550972 0.995949383 1.10812291 0.335538852 0.065769098 0.13309155 6.270446719 0.008201005 0.013389298 5.61E-07 6.250856407 0.112173526 DMAIATGGAVFGEEGLTLNLEDVQPHDLGK ddPTM_HeLa_Curcumin_4h_R1 3 DMAIATGGAVFGEEGLTLNLEDVQPHDLGK 30 0 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 ;; ;; 222.06 3.84E-40 4310300 1048.491 624.61 1589.902 1228.364 1068.33 862.89 574.276 574.88 122.15 0 FALSE FALSE TRUE 965.501831 678.5985052 1648.825167 1223.281355 1055.590862 683.9168872 590.388639 750.1582656 108.7504506 0 0 DMDEPS(ph)PVPNVEEVTLPK ddPTM_HeLa_Curcumin_4h_R1 4 DMDEPSPVPNVEEVTLPK 18 0 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 0 DMDEPS(1)PVPNVEEVTLPK;DMDEPS(1)PVPNVEEVTLPK;DMDEPS(1)PVPNVEEVTLPK;DMDEPS(1)PVPNVEEVTLPK ;;; 106.57 0.0010038 59116000 8824.41 8016.45 8475.28 8963.48 10463.98 10518.09 9759.86 8743.65 8946.79 8365.77 TRUE FALSE FALSE 8125.948637 8709.356217 8789.381332 8926.391495 10339.20387 8336.519571 10033.6954 11409.54863 7965.349521 8656.479885 0.938712819 1.006108295 1.015352828 1.031180297 1.194388945 0.963038057 1.159096485 1.318035597 0.920160345 1 13.07956476 -1 0.430703224 0.974486629 7.537323799 0.685500328 0.068032477 28.92817226 0.324332638 0.014799685 166.3916046 0.1 1 6.56283717 DMDRDVDR ddPTM_HeLa_Curcumin_4h_R1 2 DMDRDVDR 8 1 H0YIQ2;P49750-3;P49750-1;P49750 H0YIQ2 YLPM1 YLP motif-containing protein 1 0 0 ; ; 116.25 0.0081454 7559900 3926.4 3564.6 3620.8 3561.1 3629.3 4608.6 3530.3 3520.5 3896.4 3447.8 FALSE FALSE TRUE 3615.621297 3872.70814 3754.990033 3546.365112 3586.022968 3652.72441 3629.350717 4593.884244 3468.974668 3567.610793 1.013457327 1.085518675 1.052522332 0.994044843 1.005160926 1.023857316 1.017305678 1.287664073 0.97235233 1 11.80074252 -4.2613975 8.309063885 1.0155812 1.289495587 0.878662728 0.030021352 0.020822282 20.26851463 0.004020408 0.031742633 5.48E-05 4.2613975 0.273914387 DMDRKKIEELMEENMT(ph)LEMAQK ddPTM_HeLa_Curcumin_4h_R1 1 DMDRKKIEELMEENMTLEMAQK 22 3 Q3V6T2;Q3V6T2-3;Q3V6T2-2;Q3V6T2-4;Q3V6T2-5;A0A2U3TZV9;A0A2R8Y7B1;A0A2R8Y4X4;A0A2R8Y4W8;A0A2R8YG73;A0A2R8YG52;A0A087WXD9;A0A2R8YGU1;A0A2R8Y6B2;A0A2R8Y7D9 Q3V6T2 CCDC88A Girdin 1 0 DMDRKKIEELMEENMT(1)LEMAQK 51.819 0.0062923 0 779.82 682.24 862.57 623.05 751.82 922.43 647.69 641.48 798.78 712.61 TRUE FALSE FALSE 718.0964241 741.2097856 894.537603 620.4719842 742.8550375 731.1076201 665.8624382 837.064299 711.1558324 737.3731445 0.973857577 1.00520312 1.213141012 0.841462683 1.007434354 0.991502912 0.903019649 1.135197702 0.964444987 1 9.526251063 -4.234971196 23.40278695 0.99122453 1.135198161 0.191718587 0.090005357 4301.769428 3803420.933 0.011266457 1.047183147 5.82E-05 4.234971196 0.143973631 DMES(ph)PTKLDVTLAK ddPTM_HeLa_Curcumin_4h_R1 1 DMESPTKLDVTLAK 14 1 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;H7C456 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 DMES(0.766)PT(0.064)KLDVT(0.17)LAK 124.78 0.013293 2261100000 4597.7 3636.1 3914.2 3965.6 3932.6 4396.3 4156.4 4850.8 4600.9 3604.5 TRUE FALSE FALSE 4233.787194 3950.388282 4059.263695 3949.191398 3885.706313 3484.457823 4273.017398 6329.78659 4096.192781 3729.756107 1.135137814 1.059154585 1.088345613 1.058833684 1.041812441 0.934232085 1.145655983 1.697104692 1.098246819 1 11.86486558 -4.274074984 3.76880113 1.057099268 1.755234129 0.929714647 0.052859234 0.051027619 1.384677174 0.008610778 0.096793033 5.32E-05 4.274074984 0.698134861 DMESDYSGQGVDQLQR ddPTM_HeLa_Curcumin_4h_R1 1 DMESDYSGQGVDQLQR 16 0 P04818 P04818 TYMS Thymidylate synthase 0 0 84.507 0.0079568 0 1334.3 1158.2 1362.4 1570.1 1597.6 1477.8 1246.2 1253.1 1582.6 1082.7 FALSE FALSE TRUE 1228.688747 1258.309647 1412.891742 1563.603342 1578.549663 1171.287622 1281.165018 1635.164421 1408.992739 1120.323744 1.096726507 1.123166097 1.261145941 1.395670984 1.409012057 1.045490313 1.143566781 1.459546341 1.257665694 1 10.12969998 -7.010221757 1.723570393 1.041395675 1.280061975 0.204663156 0.137102817 0.249186504 1.45572162 0.022229951 0.029100766 9.77E-08 7.010221757 0.238666301 DMESPT(ph)KLDVTLAK ddPTM_HeLa_Curcumin_4h_R1 2 DMESPTKLDVTLAK 14 1 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;H7C456 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 DMES(0.137)PT(0.638)KLDVT(0.225)LAK;DMES(0.315)PT(0.685)KLDVTLAK ; 142.19 0.0027444 3268180000 9360.2 7466 8511.2 9263.7 8052.2 9783.1 9066.2 9782.5 10198.7 8010.4 TRUE FALSE FALSE 8619.330293 8111.327772 8826.632559 9225.369264 7956.182774 7753.974782 9320.573172 12765.13922 9079.928126 8288.760804 1.039881654 0.978593539 1.064891697 1.112997405 0.959876025 0.935480582 1.124483308 1.540053998 1.095450616 1 13.01694071 -4.288993321 3.157527973 1.017749711 1.601671858 0.88593699 0.055343292 0.064298948 1.009395512 0.006898262 0.089096955 5.14E-05 4.288993321 0.583922148 DMGIQDDELSLR ddPTM_HeLa_Curcumin_4h_R1 2 DMGIQDDELSLR 12 0 Q96S82;H3BSE0;H3BSQ2 Q96S82 UBL7 Ubiquitin-like protein 7 0 0 ; ; 155.26 0.0018078 9989900 2826.5 2452.7 2627.5 2585.7 2652.5 3208.7 2382 1930.3 2429.5 2438.8 FALSE FALSE TRUE 2602.779542 2664.700459 2724.877461 2575.001059 2620.87067 2543.17945 2448.832509 2518.839584 2162.989928 2523.548118 1.031396835 1.055934079 1.079780267 1.020389126 1.03856576 1.007779258 0.970392635 0.998134161 0.857122522 1 11.30123788 -4.975582746 5.460040068 1.025069498 0.984755135 0 0.057805704 0.176746078 15.37867697 0.003859326 0.011618402 1.06E-05 4.975582746 -0.040314363 DMGKLY(ph)S(ph)T(ph)ILY(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 DMGKLYSTILYK 12 1 H0Y786;A0A087X1N7;P20929-4;P20929;P20929-3;P20929-2 H0Y786 NEB Nebulin 4 0 DMGKLY(1)S(1)T(1)ILY(1)K 56.205 0.015078 7255100 1145.4 886.28 982.82 1200.9 1148.4 1380.8 736.65 964.36 1401.1 947.01 TRUE FALSE FALSE 1054.740381 962.886094 1019.244174 1195.930994 1134.70608 1094.406515 757.3184164 1258.388925 1247.402835 979.918527 1.076355179 0.982618521 1.040131547 1.220439211 1.157959615 1.116834191 0.772838145 1.284177092 1.272965865 1 9.936517995 -9.329359224 0.408285536 0.97567096 1.082425541 0 0.157050481 6.781149066 1.429485007 0.31540483 0.043588995 4.68E-10 9.329359224 0.106754581 DMLPSPEQTLS(ph)PLSK ddPTM_HeLa_Curcumin_4h_R1 1 DMLPSPEQTLSPLSK 15 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 0 DMLPS(0.001)PEQT(0.019)LS(0.773)PLS(0.207)K 111.34 0.0021575 0 1886.8 1966.3 1898.5 2269.6 2256 2504.9 2050.6 2258.9 2003.3 1956 TRUE FALSE FALSE 1737.457789 2136.25821 1968.86008 2260.208997 2229.098673 1985.355504 2108.134317 2947.628211 1783.543002 2023.970854 0.858440123 1.055478742 0.972770964 1.11672013 1.101349196 0.980920995 1.041583337 1.456359021 0.881209825 1 10.9829728 -1.202496335 0.936377144 0.963179346 199.9997141 0.71613051 0.084345637 308.5360001 0.837045791 0.014751451 131076.6793 0.062734099 1.202496335 199.0365348 DMPGGFLFEGLS(ph)DDEDDFHPNTR ddPTM_HeLa_Curcumin_4h_R1 7 DMPGGFLFEGLSDDEDDFHPNTR 23 0 Q96S82;H3BUV9 Q96S82 UBL7 Ubiquitin-like protein 7 1 0 DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR;DMPGGFLFEGLS(1)DDEDDFHPNTR ;;;;;; 157.61 3.46E-07 594983000 21801.2 19115.1 19230.9 19055 20042.7 24501.2 18172.4 19177.7 23661 18486.6 TRUE FALSE FALSE 20075.61202 20767.32407 19943.61407 18976.15546 19803.70389 19419.37493 18682.26864 25024.89245 21065.4475 19129.00797 1.049485266 1.085645638 1.042584858 0.992009386 1.035270826 1.015179405 0.976645975 1.308216949 1.101230525 1 14.22347444 -4.255439181 24.99491077 1.025057219 1.308217073 0.821798745 0.038265969 166.7979294 694807.202 0.004510615 0.054472076 5.55E-05 4.255439181 0.283159854 S(ph)PGSTPT(ph)TPTSSQAPQK ddPTM_HeLa_Curcumin_4h_R1 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 0 S(0.579)PGS(0.33)T(0.096)PT(0.918)T(0.07)PT(0.006)S(0.001)SQAPQK 125.41 0.0018838 124010000 4166.5 4195.6 3950.8 4264.1 4788.6 5456.6 6794.4 8140.5 4145 4194.9 TRUE FALSE FALSE 3836.717129 4558.248969 4097.220123 4246.456284 4731.499073 4324.839651 6985.032578 10622.50098 3690.30387 4340.672463 0.883899249 1.050125069 0.943913681 0.978294566 1.090038263 0.996352452 1.609205172 2.447201687 0.850168701 1 12.08370285 -4.33314632 1.629588182 0.959687446 2.868981189 0.976121545 0.072045647 0.081604677 0.228267687 0.00980067 0.234013356 4.64E-05 4.33314632 1.909293743 up SPGS(ph)TPTTPTS(ph)SQAPQK ddPTM_HeLa_Curcumin_4h_R1 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 0 S(0.047)PGS(0.947)T(0.006)PT(0.007)T(0.03)PT(0.352)S(0.528)S(0.084)QAPQK 181.51 1.64E-05 113980000 3953.9 3494.7 3757.5 3491.7 4156.7 4579.7 5836.3 7141.1 3179.7 3220.1 TRUE FALSE FALSE 3640.944643 3796.766296 3896.756255 3477.252271 4107.134067 3629.818596 6000.05087 9318.388516 2830.894865 3331.998235 1.09272106 1.139486287 1.169495294 1.043593671 1.232633926 1.089381908 1.800736509 2.79663669 0.849608753 1 11.70217192 -4.332786771 1.697439121 1.069286766 3.260701338 0.963985897 0.103584552 0.079311798 0.246375488 0.011696336 0.26858474 4.65E-05 4.332786771 2.191414573 up DMSPLSETEMALGKDVT(ph)PPPETEVVLIK ddPTM_HeLa_Curcumin_4h_R1 2 DMSPLSETEMALGKDVTPPPETEVVLIK 28 1 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 DMS(0.002)PLS(0.02)ET(0.02)EMALGKDVT(0.957)PPPET(0.002)EVVLIK;DMS(0.004)PLS(0.018)ET(0.018)EMALGKDVT(0.959)PPPET(0.002)EVVLIK ; 71.002 0.0001376 163145000 4727.1 3524.3 3462.2 4428.5 4143 4775 4291.8 3711.6 4645 4231.3 TRUE FALSE FALSE 4352.945047 3828.924788 3590.512178 4410.17604 4093.597431 3784.611175 4412.216357 4843.249754 4135.455121 4378.33736 0.994200467 0.874515706 0.820062933 1.007271865 0.934966197 0.864394601 1.007737868 1.10618469 0.944526376 1 12.09616741 -7.474229478 24.97440346 0.997441422 0.941019672 0.022172676 0.079930006 671.9590508 344956.4291 0.013517731 0.01542268 3.36E-08 7.474229478 -0.05642175 DNDFIYHDR ddPTM_HeLa_Curcumin_4h_R1 2 DNDFIYHDR 9 0 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 0 ; ; 152.04 0.0012379 162074000 25983 22175 22307 23779 24010 26807 19975.2 20967 25352 20815 FALSE FALSE TRUE 23926.41813 24091.70819 23133.71704 23680.6088 23723.69643 21246.92602 20535.65035 27359.74178 22570.94903 21538.3197 1.110876729 1.118550961 1.074072507 1.099464077 1.101464588 0.986470919 0.953447188 1.270282091 1.04794382 1 14.39461808 -9.389986473 1.118640933 1.000068972 1.084726832 0.081763297 0.0810681 0.795523704 1.782964995 0.052150655 0.013397543 4.07E-10 9.389986473 0.084657861 DNEESEQPPVPGT(ph)PTLR ddPTM_HeLa_Curcumin_4h_R1 1 DNEESEQPPVPGTPTLR 17 0 A0A2R8YDC1;A0A2R8Y6V8;O15439-4;O15439-3;O15439-2;O15439 A0A2R8YDC1 ABCC4 Multidrug resistance-associated protein 4 1 0 DNEESEQPPVPGT(0.984)PT(0.016)LR 130.56 0.0014111 0 1573.2 1476.8 1735 1787.9 1398.6 2232.2 1455.1 865.77 2132.5 1846.9 TRUE FALSE FALSE 1448.67956 1604.448012 1799.300626 1780.502144 1381.922608 1769.216558 1495.92619 1129.739287 1898.570085 1911.079638 0.758042486 0.839550577 0.941510019 0.931673442 0.723110948 0.925768096 0.782764967 0.591152386 0.993454196 1 10.90017218 -13.52287874 0.310046111 2.762333558 0.800677717 0.35331802 0.101731391 44.38298328 0.599983673 49.04902596 0.041135774 3.00E-14 13.52287874 -1.961655841 DNGNGTYSCSYVPR ddPTM_HeLa_Curcumin_4h_R1 2 DNGNGTYSCSYVPR 14 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 321.79 6.01E-155 8714900 1116.84 337.94 885.69 550.6 909.46 1200.28 710.19 884.89 911.06 719.28 FALSE FALSE TRUE 1028.440936 367.1500278 918.5144505 548.3217631 898.6152835 951.3283981 730.11602 1154.688887 811.1189974 744.2749265 1.381802475 0.493298934 1.234106401 0.736719381 1.207370088 1.278194877 0.980976242 1.551427902 1.089810994 1 9.539691824 -4.250423515 23.79797717 1.110235534 1.55142841 0.221557913 0.260026956 1065.377815 2301486.374 0.036606979 0.699352764 5.62E-05 4.250423515 0.441192876 DNLAEDIMR ddPTM_HeLa_Curcumin_4h_R1 4 DNLAEDIMR 9 0 P08670;B0YJC4 P08670 VIM Vimentin 0 0 ;;; ;;; 147.4 0.0020001 111708000 18166.9 14716.8 16470.3 15476 17777.8 19420.6 17681.1 15683.3 14924.5 14018.1 FALSE FALSE TRUE 16728.9707 15988.85462 17080.70381 15411.96441 17565.81135 15392.54864 18177.18408 20465.06597 13287.31969 14505.22793 1.153306296 1.102282204 1.177555009 1.062511012 1.210998643 1.061172476 1.253147084 1.410875173 0.916036601 1 13.82428535 -1 0.537210093 1.079213084 14.38608679 0.621406839 0.081613089 53.32421597 0.462506013 0.013878115 818.4751048 0.1 1 13.30687371 DNLAQQS(ph)FNMEQANYTIQSLKDTK ddPTM_HeLa_Curcumin_4h_R1 1 DNLAQQSFNMEQANYTIQSLKDTK 24 1 Q9NZZ3-2;Q9NZZ3 Q9NZZ3-2 CHMP5 Charged multivesicular body protein 5 1 0 DNLAQQS(0.992)FNMEQANY(0.007)T(0.001)IQSLKDTK 50.891 0.0093608 8583700 327.13 207.39 286.96 356.61 188.91 435.59 422.24 235.3 355.14 411.31 TRUE FALSE FALSE 301.2373153 225.3158675 297.59499 355.1344423 186.6573716 345.2437239 434.086918 307.0418868 316.1820305 425.6029919 0.707789468 0.529403862 0.699231433 0.834426564 0.438571568 0.811187258 1.019933897 0.721427933 0.742903684 1 8.733364482 -9.095122999 0.937092967 0.994884368 0.722859392 0.034168342 0.169398384 0.532666047 0.867885896 0.09312342 0.029667288 8.03E-10 9.095122999 -0.272024976 DNLTLWTSDQQDDDGGEGNN ddPTM_HeLa_Curcumin_4h_R1 6 DNLTLWTSDQQDDDGGEGNN 20 0 P61981 P61981 YWHAG "14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed" 0 0 ;;;;; ;;;;; 234.52 7.87E-25 581554000 52490.2 42700.1 45921.7 47146.7 46805.3 58240.6 44591.2 45812.6 51046.8 45766.8 FALSE FALSE TRUE 48335.54528 46390.90638 47623.5986 46951.61945 46247.17737 46160.84305 45842.30906 59780.65084 45447.09375 47357.19289 1.020659003 0.979595781 1.005625454 0.991435864 0.976560783 0.974737737 0.968011537 1.262335185 0.959666124 1 15.53129595 -4.257211784 24.99592963 0.999795318 1.262335288 0.933938767 0.021761246 74.50805967 440516.8879 0.002925637 0.030309045 5.53E-05 4.257211784 0.26253997 DNLTLWTSDQQDEEAGEGN ddPTM_HeLa_Curcumin_4h_R1 4 DNLTLWTSDQQDEEAGEGN 19 0 Q04917 Q04917 YWHAH 14-3-3 protein eta 0 0 ;;; ;;; 246.63 7.75E-33 92029200 25419.1 19624.3 20970.9 22889.4 23193.3 27027.9 21739.2 21564.2 24637.3 21559.9 FALSE FALSE TRUE 23407.15141 21320.53705 21748.1 22794.68973 22916.73505 21422.00887 22349.14344 28139.02531 21934.64983 22309.10492 1.049219657 0.955687695 0.974853096 1.021766216 1.027236867 0.960236143 1.001794717 1.261324711 0.983215145 1 14.44534501 -4.260182893 24.97707937 1.010840965 1.261324793 0.862792445 0.031179347 31.42569728 624622.6573 0.004739789 0.039355045 5.49E-05 4.260182893 0.250483827 DNLTLWTSDS(ph)AGEECDAAEGAEN ddPTM_HeLa_Curcumin_4h_R1 2 DNLTLWTSDSAGEECDAAEGAEN 23 0 P27348 P27348 YWHAQ 14-3-3 protein theta 1 0 DNLTLWT(0.002)S(0.015)DS(0.982)AGEECDAAEGAEN;DNLTLWT(0.002)S(0.027)DS(0.971)AGEECDAAEGAEN ; 118.22 2.22E-06 8906100 10495.5 9083.8 8080.6 9930.1 8712.8 12126.5 7872.5 8169.2 10027.5 8730.2 TRUE FALSE FALSE 9664.7701 9868.963195 8380.074144 9889.011877 8608.905551 9611.327206 8093.381162 10659.95147 8927.508338 9033.5738 1.069872269 1.092476069 0.92765879 1.094695421 0.952990006 1.063956239 0.895922405 1.180037016 0.988258748 1 13.14108113 DNLTLWTSDSAGEECDAAEGAEN ddPTM_HeLa_Curcumin_4h_R1 1 DNLTLWTSDSAGEECDAAEGAEN 23 0 P27348 P27348 YWHAQ 14-3-3 protein theta 0 0 124.76 4.35E-06 3006000 2475.7 2152.3 2030.6 2436.2 2263.4 2189.9 1265 1315.6 2470.6 1881.4 FALSE FALSE TRUE 2279.745733 2338.335222 2105.855822 2426.11965 2236.410433 1735.690055 1300.492495 1716.720384 2199.581361 1946.77851 1.17103498 1.201130591 1.081713103 1.246222741 1.148774975 0.891570379 0.668022833 0.881826245 1.129857018 1 10.92687304 -5.095745198 3.951619193 1.108040432 0.774457471 0.760651561 0.083926406 0.099340441 2.772674744 0.01402787 0.039206006 8.02E-06 5.095745198 -0.333582961 DNLTLWTSDTQGDEAEAGEGGEN ddPTM_HeLa_Curcumin_4h_R1 3 DNLTLWTSDTQGDEAEAGEGGEN 23 0 P63104;B0AZS6;P63104-2;B7Z2E6;H0YB80 P63104 YWHAZ 14-3-3 protein zeta/delta 0 0 ;; ;; 218.14 3.12E-23 13258600 13357.8 11302.6 11319.2 11216 11457.1 14326.1 10910.5 10593.4 13270.8 11193.4 FALSE FALSE TRUE 12300.51603 12279.54638 11738.69951 11169.59116 11320.48157 11354.70537 11216.61927 13823.27889 11815.02644 11582.36982 1.062003392 1.060192912 1.013497211 0.964361468 0.977389062 0.98034388 0.968421786 1.19347587 1.020087135 1 13.49964285 -6.545045745 23.72734048 1.032626908 1.007799471 0.010852282 0.065143237 431.8719859 462269.0627 0.010127621 0.01432352 2.85E-07 6.545045745 -0.024827437 DNLTLWTSENQGDEGDAGEGEN ddPTM_HeLa_Curcumin_4h_R1 9 DNLTLWTSENQGDEGDAGEGEN 22 0 P31946-2;P31946 P31946-2 YWHAB "14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed" 0 0 ;;;;;;;; ;;;;;;;; 258.09 2.90E-47 339740900 113566.5 92499.5 94383.5 100128.7 100616.4 120619.5 94121.7 91951.6 112825.1 96780.7 FALSE FALSE TRUE 104577.5917 100494.7446 97881.43554 99714.39397 99416.61514 95601.65604 96762.50159 119987.2195 100448.4688 100143.8221 1.04427402 1.003504185 0.977408626 0.995711886 0.992738374 0.954643572 0.966235356 1.198148992 1.003042092 1 16.6117139 -4.254011785 24.9616799 1.00652775 1.198149085 0.838840037 0.026380268 339.2415503 1140049.954 0.004589086 0.065107617 5.57E-05 4.254011785 0.191621335 DNMAQEGVILDDVDSSVCR ddPTM_HeLa_Curcumin_4h_R1 2 DNMAQEGVILDDVDSSVCR 19 0 S4R338;Q9BV86 S4R338 NTMT1 "N-terminal Xaa-Pro-Lys N-methyltransferase 1;N-terminal Xaa-Pro-Lys N-methyltransferase 1, N-terminally processed" 0 0 ; ; 183.06 4.79E-16 6406500 1647.71 1809.88 1609.25 1833.05 2018.47 2132.27 1557.08 1556.39 1908.07 1773.94 FALSE FALSE TRUE 1517.292015 1966.317963 1668.890221 1825.465325 1994.401064 1690.013166 1600.767474 2030.926146 1698.759495 1835.584283 0.826598936 1.071221834 0.909187465 0.994487337 1.086521105 0.920694943 0.872075169 1.106419446 0.925459817 1 10.84202364 -7.257695672 24.99022888 0.918116165 0.987107224 0.147061839 0.08372396 572.3635187 3820677.928 0.015731551 0.018882636 5.52E-08 7.257695672 0.068991059 DNPAQDFSTLYGSS(ph)PLER ddPTM_HeLa_Curcumin_4h_R1 2 DNPAQDFSTLYGSSPLER 18 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 0 DNPAQDFSTLYGS(0.018)S(0.982)PLER;DNPAQDFSTLYGS(0.038)S(0.962)PLER ; 235.79 2.66E-24 32434000 4155.4 3437.7 4054 4017.9 3566.5 6322 4928.7 3376.1 4339.4 3037.1 TRUE FALSE FALSE 3826.495705 3734.83947 4204.244806 4001.274994 3523.971817 5010.745936 5066.986057 4405.457348 3863.378677 3142.638999 1.217605874 1.188440502 1.337807113 1.273221326 1.121341592 1.594438922 1.612334748 1.401833729 1.22934218 1 11.61776084 -1.000000083 0.107075969 0.831134093 3.007928151 0.474433264 0.134235794 47.33871871 0.35704994 0.76801575 15.26171148 0.099999981 1.000000083 2.176794058 DNPFSLGES(ph)FGSR ddPTM_HeLa_Curcumin_4h_R1 1 DNPFSLGESFGSR 13 0 Q8N6H7;E9PMU9;H0YDN9;A0A0D9SF70;G5E9L0;Q8N6H7-3;Q8N6H7-2;E9PQP3 Q8N6H7 ARFGAP2 ADP-ribosylation factor GTPase-activating protein 2 1 0 DNPFS(0.005)LGES(0.991)FGS(0.005)R 113.43 0.0034986 0 831.77 672.93 795.54 752.56 546.2 839.81 707.69 685.13 766.14 795.64 TRUE FALSE FALSE 765.9345268 731.0950707 825.0234122 749.4461061 539.6869217 665.6239394 727.5458767 894.022983 682.0963588 823.2884308 0.930335589 0.888018152 1.00210738 0.910308074 0.655525939 0.808494222 0.883707155 1.085917097 0.8285023 1 9.685254143 -5.99633994 24.99963794 0.961235893 0.847435551 0.046520949 0.111194339 135.0212861 922231.6457 0.015398115 0.027818563 1.01E-06 5.99633994 -0.113800342 DNPGVVTCLDEAR ddPTM_HeLa_Curcumin_4h_R1 4 DNPGVVTCLDEAR 13 0 P22314;P22314-2;Q5JRR9;Q5JRS0 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 0 ;;; ;;; 246.51 1.78E-49 37379700 2701.86 1962.7 2213.43 2314.31 1934.49 2434.44 2255.77 1936.92 2313.58 2073.96 FALSE FALSE TRUE 2488.00493 2132.347042 2295.461663 2304.733998 1911.42247 1929.509702 2319.060835 2527.477992 2059.786062 2146.029956 1.159352377 0.993624081 1.069631697 1.073952389 0.890678373 0.899106602 1.080628362 1.177745905 0.959812353 1 11.0674545 DNPS(ph)PGPSR ddPTM_HeLa_Curcumin_4h_R1 2 DNPSPGPSR 9 0 Q9NQS1 Q9NQS1 AVEN Cell death regulator Aven 1 0 DNPS(0.996)PGPS(0.004)R;DNPS(0.945)PGPS(0.055)R ; 125.36 0.0048475 36138000 6897.2 7837.6 6987.3 6276.4 7348.6 9073.2 8185.3 6143.8 6325.2 6288.1 TRUE FALSE FALSE 6351.279342 8515.04722 7246.255485 6250.42992 7260.972745 7191.316044 8414.957488 8017.016337 5631.341385 6506.611007 0.976127101 1.308676239 1.113675841 0.96062757 1.115937734 1.105232207 1.293293464 1.232133953 0.865479952 1 12.66769059 -1 0.202608918 0.968293455 2.442158648 0.414016125 0.10785663 37.54687408 0.433378343 0.097323891 17.77862701 0.1 1 1.473865193 DNQESS(ph)DAELSSSEYIK ddPTM_HeLa_Curcumin_4h_R1 2 DNQESSDAELSSSEYIK 17 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 DNQES(0.177)S(0.823)DAELSSSEYIK;DNQES(0.01)S(0.99)DAELSSSEYIK ; 213.36 2.28E-15 72423000 6869.2 4662.4 5770.3 5969.4 6190.8 6360.1 5753.3 3700.4 6049.6 5294.2 TRUE FALSE FALSE 6325.495572 5065.397081 5984.152394 5944.700204 6116.978753 5040.943567 5914.722114 4828.634925 5385.974015 5478.173056 1.154672462 0.924650797 1.092362788 1.085161083 1.116609258 0.920186989 1.079688804 0.881431615 0.983169747 1 12.41947913 -3.144907348 0.868676578 1.065193543 1.84E-13 0.197859464 0.080298478 13.54887814 1.728265404 0.012805162 21.67313719 0.000716296 3.144907348 -1.065193543 DNQESSDAELS(ph)SSEYIK ddPTM_HeLa_Curcumin_4h_R1 1 DNQESSDAELSSSEYIK 17 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 DNQES(0.052)S(0.247)DAELS(0.692)S(0.007)S(0.002)EYIK 198.67 4.08E-08 37882000 3254.5 2928.7 3341.4 2629.5 3510.1 3515.1 2715.7 2051.6 2429.9 2788.4 TRUE FALSE FALSE 2996.902891 3181.843778 3465.235223 2618.619826 3468.24435 2786.028637 2791.895233 2677.123396 2163.346049 2885.296692 1.038681013 1.102778715 1.200997884 0.907573849 1.202040802 0.9655952 0.967628473 0.927850298 0.749782875 1 11.49450396 -5.030789252 24.9936222 1.042878119 0.952457383 0.062086345 0.126817423 802.1527962 651159.3322 0.011808276 0.03014711 9.32E-06 5.030789252 -0.090420736 DNQLSEVANK ddPTM_HeLa_Curcumin_4h_R1 2 DNQLSEVANK 10 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2;S4R349;S4R402;S4R341 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 0 ; ; 161.17 5.04E-09 5636400 4009.3 2958.4 3136.7 3628.3 3654 5030.1 3533.6 3234.1 3946.8 3732.2 FALSE FALSE TRUE 3691.959674 3214.110914 3252.948861 3613.287056 3610.428437 3986.800559 3632.743306 4220.162202 3513.845914 3861.893672 0.955997235 0.832262922 0.842319633 0.935625722 0.93488551 1.03234343 0.94066373 1.092770169 0.909876401 1 11.91509273 -4.257477056 24.07439906 0.955661504 1.092770261 0.317304112 0.062509205 254.8139334 1548094.999 0.009477717 0.095533864 5.53E-05 4.257477056 0.137108757 DNS(ph)PEPNDPEEPQEVSSTPSDKK ddPTM_HeLa_Curcumin_4h_R1 2 DNSPEPNDPEEPQEVSSTPSDKK 23 1 G5E9C0;Q9HB58-5;Q9HB58-3;Q9HB58-7;Q9HB58;Q9HB58-6;Q9HB58-2 G5E9C0 SP110 Sp110 nuclear body protein 1 0 DNS(1)PEPNDPEEPQEVSSTPSDKK;DNS(1)PEPNDPEEPQEVSSTPSDKK ; 169.84 2.52E-09 74604000 8351.7 7201.8 8035.9 7311.8 9103.7 7513.7 6784 4543 7489.6 6930.3 TRUE FALSE FALSE 7690.654132 7824.291501 8333.717523 7281.545709 8995.144323 5955.273923 6974.340782 5928.139787 6668.009618 7171.127409 1.072447008 1.091082483 1.162120968 1.015397621 1.25435567 0.830451557 0.972558481 0.826667754 0.929841186 1 12.80798423 -5.223894553 24.99002441 1.060413842 0.886159157 0.485240496 0.092669361 374.1939203 249064.9232 0.011637685 0.029669582 5.97E-06 5.223894553 -0.174254685 DNSDFDLLTVSETANEPPQDEGNS(ph)FNSPR ddPTM_HeLa_Curcumin_4h_R1 1 DNSDFDLLTVSETANEPPQDEGNSFNSPR 29 0 O15371-2;O15371-3;O15371 O15371-2 EIF3D Eukaryotic translation initiation factor 3 subunit D 1 0 DNSDFDLLT(0.006)VS(0.01)ET(0.01)ANEPPQDEGNS(0.659)FNS(0.315)PR 63.728 0.00051076 2716500 545.34 482.86 478.15 625.9 493.16 547.44 294.3 488.36 654.24 484.35 TRUE FALSE FALSE 502.1757636 524.5962668 495.8706596 623.3101916 487.2793891 433.8947731 302.5572659 637.2587159 582.4715088 501.1811264 1.001984586 1.046719916 0.989404097 1.243682491 0.972262049 0.865744439 0.603688467 1.271513795 1.162197613 1 8.969188276 -5.428444029 5.438818483 1.022104256 0.885332285 0.103165339 0.173356153 0.350661646 15.93165632 0.021856855 0.049425373 3.73E-06 5.428444029 -0.136771971 DNSTMGYMAAK ddPTM_HeLa_Curcumin_4h_R1 3 DNSTMGYMAAK 11 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 ;; ;; 167.12 1.02E-08 10602700 4018.61 2713 3405.9 3226.703 3473.06 4639.62 3486.2 3258.1 3178.42 3402.34 FALSE FALSE TRUE 3700.532778 2947.499631 3532.12565 3213.351758 3431.646028 3677.310513 3584.013389 4251.479692 2829.755278 3520.571062 1.051117195 0.837222024 1.003282021 0.912735946 0.974741304 1.04452103 1.018020465 1.207610816 0.80377735 1 11.78159375 -3.86700687 1.593147877 0.998672716 1.551015357 0.353858089 0.087733783 2.281199803 2.34703073 0.009615884 2.664338879 0.000135829 3.86700687 0.552342641 DNSTMGYMMAK ddPTM_HeLa_Curcumin_4h_R1 1 DNSTMGYMMAK 11 0 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 0 150.46 5.46E-06 3949600 1503.6 1065.4 1384.8 1041.1 1351.6 1337.3 1264.5 1169.9 1488.5 1258.7 FALSE FALSE TRUE 1384.588473 1157.488429 1436.121906 1036.792204 1335.483053 1059.928906 1299.978467 1526.597124 1325.215274 1302.439731 1.06307297 0.888707862 1.102639816 0.796038526 1.025370327 0.813802651 0.998110266 1.17210577 1.01748683 1 10.3470009 -7.29176194 24.86529598 1.029784456 0.966395636 0.048296014 0.112183333 1363.910414 1118438.678 0.018054658 0.020647675 5.11E-08 7.29176194 -0.06338882 DNTFFRES(ph)PVGR ddPTM_HeLa_Curcumin_4h_R1 1 DNTFFRESPVGR 12 1 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;F8VPY7;F8VWU8 F8WF16 PPHLN1 Periphilin-1 1 0 DNT(0.002)FFRES(0.998)PVGR 67.648 0.017573 370580000 6860.9 6136.1 5698.6 6003.2 5890.7 7051.2 6338.6 2079.1 6598.6 5855.8 TRUE FALSE FALSE 6317.852525 6666.477142 5909.795129 5978.360349 5820.45725 5588.701637 6516.444057 2713.008019 5874.750089 6059.288614 1.042672321 1.10020789 0.975328212 0.986643933 0.960584257 0.922336266 1.075447049 0.447743653 0.969544523 1 12.56493271 -4.257579334 24.99977154 1.012914089 0.447743436 0.909762175 0.052449417 76.13830292 493093.0128 0.007084992 0.071953649 5.53E-05 4.257579334 -0.565170653 DNTRPGANS(ph)PEMWSEAIK ddPTM_HeLa_Curcumin_4h_R1 1 DNTRPGANSPEMWSEAIK 18 1 F1T0B3;A0A087X2G1;Q92499-3;Q92499-2;Q92499 F1T0B3 DDX1 ATP-dependent RNA helicase DDX1 1 0 DNT(0.008)RPGANS(0.989)PEMWS(0.003)EAIK 94.325 0.0042612 11008000 3911.1 2507.3 2883.7 2974.2 2945 3656.3 2761.7 2916.3 3745.1 3279.8 TRUE FALSE FALSE 3601.532308 2724.01984 2990.572459 2961.893548 2909.882798 2897.942165 2839.185869 3805.466445 3334.2719 3393.772806 1.061217858 0.802652386 0.881194066 0.872743615 0.857418267 0.853899872 0.836586899 1.121308544 0.982467622 1 11.72867427 -7.273764084 24.69386114 1.028908436 0.883817448 0.311156679 0.084248655 453.2277017 908088.3139 0.013519908 0.015521859 5.32E-08 7.273764084 -0.145090988 DNTRPGANSPEMWS(ph)EAIK ddPTM_HeLa_Curcumin_4h_R1 1 DNTRPGANSPEMWSEAIK 18 1 F1T0B3;A0A087X2G1;Q92499-3;Q92499-2;Q92499 F1T0B3 DDX1 ATP-dependent RNA helicase DDX1 1 0 DNT(0.01)RPGANS(0.329)PEMWS(0.662)EAIK 68.463 0.0091 0 1900.4 1446.9 1782.2 1648.2 1471.4 1856.3 1503.8 1830.8 1922.8 1743 TRUE FALSE FALSE 1749.981335 1571.963589 1848.2499 1641.380185 1453.854516 1471.282455 1545.992581 2389.002492 1711.873651 1803.56912 0.970287922 0.871584887 1.024773533 0.910073347 0.806098585 0.815761613 0.857185102 1.324597136 0.949158882 1 10.816639 -7.487701769 9.461103867 0.986954878 0.931631711 0.001621389 0.142651327 1.285025291 331.6840424 0.023672716 0.026352436 3.25E-08 7.487701769 -0.055323167 DNYVPEVSALDQEIIEVDPDTK ddPTM_HeLa_Curcumin_4h_R1 1 DNYVPEVSALDQEIIEVDPDTK 22 0 H0YN88;A0A075B716;H3BNC9;P08708 H0YN88 RPS17 40S ribosomal protein S17 0 0 63.536 0.0047835 2584200 2744.4 2798.2 3613.7 2805.6 3557.6 3487.2 2991.6 2735.2 3175 3241.8 FALSE FALSE TRUE 2527.177844 3040.063939 3747.626901 2793.991171 3515.177944 2763.915411 3075.536245 3569.149889 2826.710443 3354.452309 0.753380168 0.906277288 1.117209773 0.832920225 1.047914121 0.823954302 0.916851981 1.064003766 0.842674208 1 11.71186152 -6.986913333 24.99545532 0.88071368 0.960570415 0.154573248 0.10565186 461.6178493 881684.0926 0.019709981 0.025896345 1.03E-07 6.986913333 0.079856735 DPAQPMS(ph)PGEATQSGAR ddPTM_HeLa_Curcumin_4h_R1 5 DPAQPMSPGEATQSGAR 17 0 Q9BQG0;Q9BQG0-2 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 0 DPAQPMS(0.994)PGEAT(0.006)QSGAR;DPAQPMS(0.999)PGEAT(0.001)QSGAR;DPAQPMS(0.991)PGEAT(0.007)QS(0.002)GAR;DPAQPMS(1)PGEATQSGAR;DPAQPMS(0.998)PGEAT(0.002)QSGAR ;;;; 206.45 9.00E-11 109284300 12295 12078 14132.6 13939.97 15797.3 15635.9 14458.33 10991.07 12154.75 10974.06 TRUE FALSE FALSE 11321.83778 13121.9685 14656.36659 13882.2901 15608.92752 12392.83809 14863.99183 14342.19665 10821.40433 11355.40777 0.9970437 1.155569995 1.290694873 1.22252678 1.374580978 1.091360023 1.308979134 1.263027884 0.952973645 1 13.47109189 -7.090883297 2.873298936 0.998001638 1.256549128 0.753574931 0.07007485 0.087290674 1.398360144 0.010707885 0.01346696 8.11E-08 7.090883297 0.25854749 DPAQPMSPGEAT(ph)QSGARPADR ddPTM_HeLa_Curcumin_4h_R1 2 DPAQPMSPGEATQSGARPADR 21 1 Q9BQG0;Q9BQG0-2 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 0 DPAQPMS(0.147)PGEAT(0.691)QS(0.162)GARPADR;DPAQPMS(0.003)PGEAT(0.796)QS(0.201)GARPADR ; 70.615 0.0025161 149703000 2657.9 2102.4 2316.6 2624.8 2621.2 2930.6 2636.3 1960.4 2597.5 2761 TRUE FALSE FALSE 2447.52441 2284.122088 2402.455234 2613.939273 2589.943902 2322.760525 2710.267483 2558.116935 2312.560749 2856.944544 0.856693006 0.799498223 0.840917699 0.914942251 0.906543288 0.813022615 0.948659465 0.895403077 0.809452446 1 11.48025732 -9.190145633 0.962045753 0.999089581 0.871922214 0 0.073017196 0.34584894 0.581874558 0.029632433 0.008618675 6.45E-10 9.190145633 -0.127167367 DPAQPMSPGEATQS(ph)GARPADR ddPTM_HeLa_Curcumin_4h_R1 2 DPAQPMSPGEATQSGARPADR 21 1 Q9BQG0;Q9BQG0-2 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 0 DPAQPMS(0.038)PGEAT(0.397)QS(0.565)GARPADR;DPAQPMS(0.157)PGEAT(0.312)QS(0.531)GARPADR ; 119.37 0.0003819 92559000 2254.27 2348.14 2312.81 2378.63 2075.47 3238.5 2268.02 2041.16 2497.5 2503.66 TRUE FALSE FALSE 2075.842151 2551.102758 2398.524773 2368.787859 2050.721376 2566.798595 2331.654537 2663.500288 2223.530498 2590.661999 0.801278651 0.984730065 0.9258347 0.9143562 0.791581988 0.990788685 0.900022673 1.028115705 0.858286608 1 11.33910509 DPETYEVDS(ph)GTTK ddPTM_HeLa_Curcumin_4h_R1 1 DPETYEVDSGTTK 13 0 Q3B726 Q3B726 TWISTNB DNA-directed RNA polymerase I subunit RPA43 1 0 DPET(0.003)YEVDS(0.598)GT(0.396)T(0.002)K 125.47 0.0020024 5097500 949.72 986.98 850.8 823.58 1008.5 1162.2 1095.1 761.03 1244.4 1117.1 TRUE FALSE FALSE 874.5486599 1072.290153 882.3313964 820.1722442 996.4742962 921.1466193 1125.825559 993.0645436 1107.892433 1155.919142 0.756582903 0.927651524 0.763315845 0.709541191 0.862062285 0.796895376 0.973965668 0.859112465 0.958451498 1 10.17482477 -9.468481105 1.158912604 1.001721744 0.825018358 0.367596742 0.07690401 0.397606699 0.940217065 0.05723304 0.013538316 3.40E-10 9.468481105 -0.176703385 DPGPPRPPAGATQDEELQGS(ph)PLSR ddPTM_HeLa_Curcumin_4h_R1 1 DPGPPRPPAGATQDEELQGSPLSR 24 1 H3BPQ5;H3BME5;H3BQE6;H3BQP9;Q58EX7-3;Q58EX7-2;Q58EX7 H3BPQ5 PLEKHG4 Puratrophin-1 1 0 DPGPPRPPAGAT(0.004)QDEELQGS(0.885)PLS(0.11)R 50.413 0.010111 9719000 1075.7 920.86 907.19 940.16 967.94 1012.6 885.51 720.84 911.75 1032.9 TRUE FALSE FALSE 990.5572099 1000.455035 940.8112594 936.269867 956.3979477 802.5753456 910.3550274 940.6207977 811.7333061 1068.793198 0.926799695 0.936060444 0.880255658 0.876006573 0.894839104 0.75091734 0.85175975 0.880077455 0.759485846 1 10.06176702 -7.105689692 0.35859345 1.001169799 0.819742005 0 0.08220851 0.495688812 0.178032299 0.024949251 0.033358038 7.84E-08 7.105689692 -0.181427794 DPLEEMVPLSHLEEEQPPAPES(ph)PESR ddPTM_HeLa_Curcumin_4h_R1 1 DPLEEMVPLSHLEEEQPPAPESPESR 26 0 O60307 O60307 MAST3 Microtubule-associated serine/threonine-protein kinase 3 1 0 DPLEEMVPLSHLEEEQPPAPES(0.812)PES(0.188)R 112.9 2.86E-08 3185800 598.88 432.25 506.31 481.18 619.18 584.26 672.39 452.81 572.51 446.56 TRUE FALSE FALSE 551.4780161 469.6117639 525.074294 479.1890047 611.7966829 463.07789 691.2554538 590.8696845 509.7070853 462.0779268 1.193474053 1.016304257 1.136332778 1.037030719 1.32401192 1.002164058 1.495971596 1.278723025 1.103076031 1 8.851992364 -1 0.26468444 1.058790443 3.229569099 0.343260439 0.126861949 37.86670711 0.478559101 0.059464375 37.77844864 0.1 1 2.170778656 DPLGGLADMFGQMPGSGIGTGPGVIQDRFS(ph)PTMGR ddPTM_HeLa_Curcumin_4h_R1 1 DPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGR 35 1 H0Y3P2;D3DQV9;P78344-2;P78344;H0YCH5 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 0 DPLGGLADMFGQMPGS(0.082)GIGT(0.082)GPGVIQDRFS(0.713)PT(0.123)MGR 52.549 0.008436 7430700 498.59 368.34 554.97 451.31 444.15 701.42 627.83 300.32 580.69 445.09 TRUE FALSE FALSE 459.1260754 400.1776683 575.5376764 449.4425988 438.8538013 555.9375854 645.4452201 391.8861855 516.9897598 460.5568444 0.996893393 0.868899623 1.249656114 0.975867809 0.952876516 1.207098737 1.401445289 0.850896453 1.122531922 1 8.847235422 -5.2571156 24.83975083 1.003469323 1.177976682 0.106803868 0.159385506 375.8633858 2159292.946 0.019745961 0.048508641 5.53E-06 5.2571156 0.174507359 DPLQNS(ph)PGSEGK ddPTM_HeLa_Curcumin_4h_R1 2 DPLQNSPGSEGK 12 0 Q6IE81;Q6IE81-2 Q6IE81 JADE1 Protein Jade-1 1 0 DPLQNS(0.939)PGS(0.061)EGK;DPLQNS(0.885)PGS(0.115)EGK ; 113.54 0.0045272 38274300 5909.7 4382 5531.5 5740.2 5643.1 6316.9 5066.7 2119.35 5960.1 5132.2 TRUE FALSE FALSE 5441.941009 4760.760554 5736.502256 5716.448573 5575.809718 5006.703734 5208.857966 2765.530059 5306.291941 5310.543568 1.024742748 0.896473307 1.080209998 1.076433796 1.049950847 0.942785549 0.980852129 0.520762145 0.999199399 1 12.37464382 -4.244309153 3.65925793 1.01131491 0.45726795 0.879637144 0.05386321 0.071490368 1.690464647 0.007277359 0.109527226 5.70E-05 4.244309153 -0.55404696 DPLQNSPGS(ph)EGK ddPTM_HeLa_Curcumin_4h_R1 1 DPLQNSPGSEGK 12 0 Q6IE81;Q6IE81-2 Q6IE81 JADE1 Protein Jade-1 1 0 DPLQNS(0.444)PGS(0.556)EGK 86.262 0.018701 28827000 2644.1 2425.3 2515.1 2882.9 2217.3 2628.9 2197.7 937.71 2636.5 2260.4 TRUE FALSE FALSE 2434.816695 2634.932125 2608.311819 2870.971324 2190.860146 2083.636506 2259.361547 1223.613462 2347.282546 2338.948732 1.040987629 1.126545481 1.115164169 1.227462272 0.936685835 0.890843172 0.965973096 0.523146765 1.00356306 1 11.19164452 -3.950887601 1.201024653 1.0426788 5.04E-12 0.751043676 0.089853742 1.15879388 0.84556645 0.013817865 1.795167836 0.000111973 3.950887601 -1.0426788 DPQEKTLS(ph)IFMEY(ph)MPGGS(ph)IK ddPTM_HeLa_Curcumin_4h_R1 1 DPQEKTLSIFMEYMPGGSIK 20 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 3 0 DPQEKT(0.099)LS(0.903)IFMEY(0.999)MPGGS(1)IK 46.159 0.0085757 0 724.53 469.06 489.43 473.56 606.21 700.55 618.19 505.17 579.74 444.52 TRUE FALSE FALSE 667.182686 509.6034563 507.5687063 471.6005342 598.9813417 555.2480332 635.5347476 659.1940075 516.1439724 459.9670369 1.450501085 1.107912992 1.103489306 1.025292024 1.302226668 1.207147445 1.381696288 1.433133148 1.122132525 1 8.845386665 -9.633518407 1.463375522 1.000357414 1.270205718 0.199472359 0.142374512 0.424986798 1.63874296 0.110774585 0.025356684 2.33E-10 9.633518407 0.269848305 LGTS(ph)AEGAHLR ddPTM_HeLa_Curcumin_4h_R1 1 LGTSAEGAHLR 11 0 Q15042-4;Q15042;Q15042-3 Q15042-4 RAB3GAP1 Rab3 GTPase-activating protein catalytic subunit 1 0 LGT(0.206)S(0.794)AEGAHLR 144.28 0.00050172 8135400 4155.5 3607.4 3476.5 3872.5 3908.2 3757.7 1747.9 880.08 4279.1 3508.7 TRUE FALSE FALSE 3826.58779 3919.207582 3605.342148 3856.476621 3861.597268 2978.310662 1796.94137 1148.412341 3809.693436 3630.627064 1.053974347 1.079485035 0.993035662 1.062206763 1.063617166 0.820329549 0.494939672 0.316312395 1.049321059 1 11.82600303 -4.781559673 1.92112521 1.033298137 0.316670384 0.984116711 0.032392707 0.034086591 0.229177432 0.005168957 0.030134699 1.65E-05 4.781559673 -0.716627753 down DPS(ph)ASPGDAGEQAIR ddPTM_HeLa_Curcumin_4h_R1 1 DPSASPGDAGEQAIR 15 0 P18206;P18206-2 P18206 VCL Vinculin 1 0 DPS(0.96)AS(0.04)PGDAGEQAIR 134.02 0.00064751 25906000 633.97 549.18 996.29 641.37 869.27 957.62 967.92 869.81 597.48 457.87 TRUE FALSE FALSE 583.7906055 596.6486721 1033.213384 638.7161809 858.904523 758.9988174 995.0772302 1135.011065 531.9379388 473.7809484 1.23219519 1.259334454 2.180782886 1.348125506 1.812872649 1.602003668 2.100289667 2.395645221 1.1227508 1 8.888076376 -1 0.157124812 0.821560609 6.522086558 0.678819075 0.263892071 24.26674681 0.24268337 0.478219076 32.02185828 0.1 1 5.700525948 RRDS(ph)GDNSAPSGQER ddPTM_HeLa_Curcumin_4h_R1 1 RRDSGDNSAPSGQER 15 2 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 0 RRDS(0.999)GDNS(0.001)APSGQER 83.948 0.0091063 7050700 374.45 368.05 354.67 366.58 325.17 328.93 508.66 682.13 451.26 421.54 TRUE FALSE FALSE 344.8118874 399.862602 367.8143822 365.0631891 321.2925601 260.7062102 522.9316306 890.1082969 401.757907 436.1884836 0.790511213 0.91671976 0.843246431 0.836939082 0.736591112 0.59769164 1.198866202 2.040650614 0.921064911 1 8.76880787 -4.332085052 3.051043793 0.863791923 2.139751965 0.911228409 0.113866863 0.071965264 1.040778187 0.018127448 0.200385099 4.65E-05 4.332085052 1.275960042 up DPSASNGGGS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 1 DPSASNGGGSPAR 13 0 O60504-2;O60504;E5RIA0;E5RJP2 O60504-2 SORBS3 Vinexin 1 0 DPSASNGGGS(1)PAR 114.06 0.0034047 0 1255.9 1322.1 1295.4 1484.2 1338.3 1517.6 1421.2 840.36 1464 1382.6 TRUE FALSE FALSE 1156.49419 1436.376433 1343.408664 1478.058774 1322.341647 1202.832653 1461.075047 1096.581895 1303.402863 1430.645247 0.80837244 1.004006015 0.93902291 1.033141358 0.924297375 0.840762345 1.021269983 0.766494627 0.911059444 1 10.48245026 -4.235958406 23.31232658 0.926323895 0.766494118 0.32290764 0.07315676 3625.986633 3317254.855 0.012000257 1.009925486 5.81E-05 4.235958406 -0.159829777 DPSASNGGGS(ph)PARR ddPTM_HeLa_Curcumin_4h_R1 2 DPSASNGGGSPARR 14 1 O60504-2;O60504;E5RIA0;E5RJP2 O60504-2 SORBS3 Vinexin 1 0 DPSASNGGGS(1)PARR;DPSASNGGGS(1)PARR ; 144.15 0.00031025 41854000 1459.41 1373.44 1598.6 1178.65 2157.13 1872.61 1312.14 456.86 1321.03 1087.96 TRUE FALSE FALSE 1343.896159 1492.154034 1657.845522 1173.773059 2131.407634 1484.209577 1348.955117 596.1545109 1176.116314 1125.766529 1.193760983 1.325456029 1.47263707 1.042643415 1.89329455 1.318399099 1.198254773 0.529554304 1.044724891 1 10.13669194 -8.333383743 0.923966806 1.026915559 1.27417152 0.067183095 0.323676825 0.927713104 1.656750843 0.109376526 0.068119283 4.64E-09 8.333383743 0.247255961 DPTVHDDVLELEMDELNR ddPTM_HeLa_Curcumin_4h_R1 1 DPTVHDDVLELEMDELNR 18 0 P78527-2;P78527 P78527-2 PRKDC DNA-dependent protein kinase catalytic subunit 0 0 193.32 4.26E-09 4508000 1045.2 911.92 1172.5 1424.3 1619.6 1354.2 1169.1 903.81 1296.9 1346.5 FALSE FALSE TRUE 962.4713171 990.7423014 1215.953881 1418.406624 1600.287328 1073.323655 1201.9018 1179.377508 1154.633315 1393.290775 0.690789988 0.711080788 0.87272083 1.01802628 1.148566657 0.770351512 0.862635296 0.846469043 0.82870951 1 10.44428066 -6.514260878 24.16041652 0.836934855 0.930522354 0.158271851 0.125053601 589.9651623 1653984.563 0.024852919 0.036207862 3.06E-07 6.514260878 0.093587499 DPVQEAWAEDVDLR ddPTM_HeLa_Curcumin_4h_R1 4 DPVQEAWAEDVDLR 14 0 P14618;P14618-3;B4DNK4;P14618-2;H3BR70 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ;;; ;;; 231.69 1.22E-19 150933100 2869.31 2714.94 2729.43 3105.4 3086.66 4012.63 3072.36 3128.55 2600.34 2296.69 FALSE FALSE TRUE 2642.201086 2949.607316 2830.585077 3092.550678 3049.853595 3180.365306 3158.562153 4082.430493 2315.089208 2376.499807 1.111803619 1.241156136 1.191073136 1.30130483 1.283338457 1.338256076 1.329081595 1.717833295 0.974159224 1 11.21462257 -1 0.194744207 0.977973172 3.816425252 0.859920486 0.074655509 12.76185441 0.144489498 0.071492019 11.04601708 0.1 1 2.83845208 DQDEQEELDFLFDEEMEQMDGRK ddPTM_HeLa_Curcumin_4h_R1 2 DQDEQEELDFLFDEEMEQMDGRK 23 1 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50 Q6PKG0 LARP1 La-related protein 1 0 0 ; ; 105.16 3.57E-05 12827100 1026.29 1215.26 1204.44 1386.4 1217.23 1383.65 1224.98 928.12 1407.84 1102.88 FALSE FALSE TRUE 945.0580636 1320.301659 1249.077606 1380.663444 1202.715327 1096.665393 1259.349642 1211.099515 1253.403474 1141.204998 0.828122962 1.15693645 1.09452518 1.209829476 1.053899457 0.960971425 1.103526224 1.061246242 1.098315795 1 10.15634225 -7.256543658 24.999752 0.918835843 1.090213659 0.180274527 0.09211221 274.9077251 1403802.788 0.014812326 0.01783653 5.54E-08 7.256543658 0.171377816 DQDMS(ph)SPTTMK ddPTM_HeLa_Curcumin_4h_R1 3 DQDMSSPTTMK 11 0 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 0 DQDMS(0.826)S(0.087)PT(0.087)T(0.001)MK;DQDMS(0.597)S(0.118)PT(0.26)T(0.024)MK;DQDMS(0.884)S(0.089)PT(0.026)T(0.001)MK ;; 164.22 0.00027619 122218000 10321.8 8315.7 9700.9 8933.3 10559.5 10692.6 10001.8 8129.8 8460.1 7357 TRUE FALSE FALSE 9504.818638 9034.472054 10060.42389 8896.336372 10433.58486 8474.83423 10282.42359 10608.5386 7532.048196 7612.655202 1.24855499 1.186770163 1.321539413 1.16862463 1.370557917 1.11325602 1.350701341 1.393539877 0.989411447 1 12.89418402 -13.19734999 0.174273151 2.35E-17 1.338830527 0.653810793 0.082661595 23.52423555 0.293372367 8.031966033 0.119941478 6.35E-14 13.19734999 1.338830527 DQDNMQAELNR ddPTM_HeLa_Curcumin_4h_R1 2 DQDNMQAELNR 11 0 P33176 P33176 KIF5B Kinesin-1 heavy chain 0 0 ; ; 244.16 2.42E-23 30041000 2780.9 2110.1 2527.2 2478.39 2808 3171.7 1850.79 2041.62 2801.8 2440.7 FALSE FALSE TRUE 2560.788831 2292.487642 2620.860255 2468.135079 2774.516434 2513.853668 1902.718186 2664.10054 2494.44955 2525.514143 1.013967329 0.907731064 1.037753149 0.977280244 1.098594693 0.99538293 0.753398349 1.054874528 0.987699695 1 11.30236141 -4.961522684 24.99999593 1.006152509 0.896699833 0.188104466 0.081276397 151.0056055 98111.86952 0.009784794 0.029354317 1.09E-05 4.961522684 -0.109452676 DQDS(ph)SDDERALEDWVSSETSALPR ddPTM_HeLa_Curcumin_4h_R1 1 DQDSSDDERALEDWVSSETSALPR 24 1 Q5TAQ8;V9GY54;Q5TAQ9-2;Q5TAQ9;V9GYQ9 Q5TAQ8 DCAF8 DDB1- and CUL4-associated factor 8 1 0 DQDS(0.5)S(0.5)DDERALEDWVSSETSALPR 82.885 8.72E-05 2272400 493.59 596.89 649.18 587.6 614.14 636.18 388.78 482.57 442.34 410.38 TRUE FALSE FALSE 454.5218307 648.4825119 673.2391819 585.1686669 606.8167816 504.2290968 399.6881205 629.7033715 393.8164087 424.6406745 1.070368097 1.527132352 1.585432631 1.378032539 1.429012382 1.187425339 0.941238427 1.482908749 0.927410944 1 8.730098757 -7.388157142 6.40329715 1.030874153 1.350058436 0.462653221 0.17805441 0.183229813 8.82084333 0.031947261 0.036379655 4.09E-08 7.388157142 0.319184283 DQDS(ph)SDDERALEDWVSSETSALPRPR ddPTM_HeLa_Curcumin_4h_R1 1 DQDSSDDERALEDWVSSETSALPRPR 26 2 Q5TAQ8;V9GY54;Q5TAQ9-2;Q5TAQ9 Q5TAQ8 DCAF8 DDB1- and CUL4-associated factor 8 1 0 DQDS(0.766)S(0.233)DDERALEDWVSSETSALPRPR 48.198 0.0077627 4732100 849.24 610.3 613.13 697.71 831.52 773.9 515.24 738.17 722.01 632.68 TRUE FALSE FALSE 782.0217579 663.0516126 635.8531372 694.8230609 821.6046671 613.3844163 529.6962477 963.2346349 642.8073094 654.6655829 1.194536231 1.012809639 0.971264037 1.061340445 1.254999023 0.936943124 0.809109661 1.471338436 0.981886518 1 9.354614325 DQEWYDAEIAR ddPTM_HeLa_Curcumin_4h_R1 1 DQEWYDAEIAR 11 0 Q8IVM0;Q8IVM0-2 Q8IVM0 CCDC50 Coiled-coil domain-containing protein 50 0 0 161.99 0.0026803 13433000 1067.9 1082.3 1105.9 967.47 1334.9 1195.1 1201.5 866.5 1150.4 1045.4 FALSE FALSE TRUE 983.3745882 1175.849189 1146.885627 963.4668655 1318.982189 947.2227884 1235.210856 1130.691861 1024.203998 1081.727572 0.909077862 1.087010463 1.06023518 0.890674224 1.219329361 0.875657432 1.141887189 1.045264899 0.946822494 1 10.07912149 -7.259390254 24.98945094 0.957064546 1.044152293 0.157096515 0.099263765 255.7020865 3118343.438 0.015534221 0.018512976 5.50E-08 7.259390254 0.087087747 DQGELER ddPTM_HeLa_Curcumin_4h_R1 2 DQGELER 7 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ; ; 104.44 0.01755 11346200 8763.2 9635.9 8856.8 7394.8 8103.8 10020.8 7251.3 6648.2 8785.6 8535.9 FALSE FALSE TRUE 8069.583473 10468.78426 9185.040799 7364.202277 8007.167478 7942.373122 7454.751962 8675.205575 7821.84166 8832.52189 0.913621678 1.185254267 1.039911467 0.833759867 0.906555067 0.899219184 0.844011717 0.98218897 0.885572859 1 13.1086097 -6.262209151 24.99951581 0.984225947 0.891499466 0.285922596 0.085193476 85.12144351 2764465.541 0.01321211 0.02092903 5.47E-07 6.262209151 -0.092726481 DQGGFGDRNEYGSR ddPTM_HeLa_Curcumin_4h_R1 1 DQGGFGDRNEYGSR 14 1 A0A087WTP3;Q92945;M0R0I5 A0A087WTP3 KHSRP Far upstream element-binding protein 2 0 0 77.204 0.019256 28973000 1941 1672.9 1714.6 1838.7 1485.1 1555.3 1444.8 1448.6 1791.3 1722.2 FALSE FALSE TRUE 1787.367802 1817.498022 1778.144584 1831.091947 1467.391152 1232.713248 1485.3372 1890.271471 1594.798872 1782.046322 1.002986163 1.019893815 0.99781053 1.027522082 0.823430421 0.691740295 0.833500892 1.060730829 0.894925599 1 10.79931912 -5.759940352 24.99999996 1.004315308 0.839532013 0.344189553 0.091584393 26.52607074 442372.7613 0.012091872 0.023187146 1.74E-06 5.759940352 -0.164783295 DQGSTYSGDLESEAVS(ph)TPHSWEEELNHYALK ddPTM_HeLa_Curcumin_4h_R1 1 DQGSTYSGDLESEAVSTPHSWEEELNHYALK 31 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5;H7C1I7;Q5VZL5-3 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 0 DQGSTYSGDLES(0.001)EAVS(0.333)T(0.333)PHS(0.333)WEEELNHY(0.001)ALK 89.631 1.47E-07 2558100 907.82 855.04 935.88 847.97 841.24 1028.9 820.45 814.04 1190.1 776.15 TRUE FALSE FALSE 835.9650891 928.9458476 970.5645361 844.4613248 831.2087624 815.4945419 843.4696189 1062.237049 1059.549007 803.1211547 1.040895367 1.156669628 1.208490812 1.051474388 1.034973064 1.015406626 1.050239573 1.322636121 1.319289127 1 9.649473831 -1.000001388 0.042169854 0.717290468 1.703099202 0 0.135560018 738.0303237 2.390420126 14.99095347 51.0987992 0.09999968 1.000001388 0.985808734 DQGTYEDYVEGLR ddPTM_HeLa_Curcumin_4h_R1 4 DQGTYEDYVEGLR 13 0 P60660-2;F8W1R7;G8JLA2;G3V1V0;P60660;G3V1Y7;J3KND3;B7Z6Z4;F8VZU9;F8VPF3;F8W180;H0YI43 P60660-2 MYL6 Myosin light polypeptide 6 0 0 ;;; ;;; 211.22 1.10E-08 78527300 7909.13 6910.89 8508.94 7956.25 7853.2 9881.6 8493.6 7182.4 8878.3 7463.44 FALSE FALSE TRUE 7283.114015 7508.236537 8824.288802 7923.329146 7759.555719 7832.044771 8731.907557 9372.280696 7904.372702 7722.793984 0.943067241 0.972217639 1.142629056 1.025966659 1.00476016 1.014146536 1.130666903 1.213586782 1.02351205 1 12.91490717 -1 0.440060451 0.979497179 6.010784823 0.561057558 0.053969449 36.11507463 0.397678782 0.012538746 163.6761906 0.1 1 5.031287644 DQHFRGDNEEQEK ddPTM_HeLa_Curcumin_4h_R1 1 DQHFRGDNEEQEK 13 1 P52298-3;P52298 P52298-3 NCBP2 Nuclear cap-binding protein subunit 2 0 0 76.073 0.012461 8086100 3424.6 2191.7 2306.1 2909 2687.4 3337.9 2817.8 3462.4 3912.6 3282.8 FALSE FALSE TRUE 3153.539296 2381.140782 2391.566095 2896.963329 2655.35451 2645.581914 2896.859884 4518.069821 3483.397569 3396.877056 0.928364272 0.700979383 0.70404847 0.852831375 0.781704627 0.778827691 0.852800922 1.330065748 1.025470605 1 11.72999329 -4.258182242 24.17718999 0.892375427 1.330066012 0.593834464 0.114439094 132.1006023 980483.0585 0.018797775 0.178879153 5.52E-05 4.258182242 0.437690585 SESGGLGVSMVEYVLSSS(ph)PGDSCLRK ddPTM_HeLa_Curcumin_4h_R1 1 SESGGLGVSMVEYVLSSSPGDSCLRK 26 1 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;H0YEH2 Q5T1Z4 PUM1 Pumilio homolog 1 1 0 SESGGLGVSMVEYVLS(0.055)S(0.243)S(0.675)PGDS(0.028)CLRK 119.29 8.53E-09 49415000 2380.5 1959.7 2132.8 2148.6 1988.7 2435.4 1056.7 736.63 2569.1 1955.2 TRUE FALSE FALSE 2192.080913 2129.087736 2211.843444 2139.709663 1964.986051 1930.270587 1086.348158 961.225096 2287.276158 2023.143054 1.083502676 1.052366382 1.093270908 1.057616592 0.971254132 0.954094958 0.536960625 0.475114745 1.130555821 1 10.98238262 -4.780564942 2.718777607 1.042079782 0.469135198 0.958999476 0.044821517 0.034919264 0.507483831 0.006218816 0.0275718 1.66E-05 4.780564942 -0.572944585 down DQIPELENNEK ddPTM_HeLa_Curcumin_4h_R1 1 DQIPELENNEK 11 0 H0YBT0;A0A087WUS5;P01106;P01106-2;A0A494C1T8 H0YBT0 MYC Myc proto-oncogene protein 0 0 99.802 0.010691 9193600 4105.4 4741.3 2778.5 2869.9 4238.1 8902.9 4295.6 3344.7 4255.5 2702.1 FALSE FALSE TRUE 3780.453258 5151.116845 2881.473654 2858.025114 4187.563425 7056.338184 4416.122975 4364.483633 3788.682297 2795.997774 1.352094516 1.842317935 1.030570797 1.022184331 1.497699127 2.523728112 1.579444382 1.56097536 1.355037666 1 11.4491475 -4.171559951 0.097147445 0.541118858 3.011329439 0.174502611 0.397204663 55.00304818 0.847888154 5.1824927 20.34162899 6.74E-05 4.171559951 2.470210581 DQITAGNAAR ddPTM_HeLa_Curcumin_4h_R1 2 DQITAGNAAR 10 0 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 0 0 ; ; 141.91 2.03E-05 9901000 2478.7 2120.46 2324.19 1949.75 2383.64 2418.63 1762.43 1637.21 2437.5 2162.66 FALSE FALSE TRUE 2282.508279 2303.743114 2410.326526 1941.682451 2355.21665 1916.978874 1811.879042 2136.387792 2170.112348 2237.812274 1.019973081 1.029462185 1.077090583 0.867669944 1.052463907 0.85663078 0.809665343 0.954676948 0.969747272 1 11.1278733 -5.252773419 24.61729088 1.007957655 0.867258441 0.464832705 0.062962604 290.2893732 824618.3198 0.007974737 0.019967319 5.59E-06 5.252773419 -0.140699213 DQLIYNLLKEEQTPQNK ddPTM_HeLa_Curcumin_4h_R1 1 DQLIYNLLKEEQTPQNK 17 1 P00338;P00338-3;P00338-4;P00338-5;P00338-2;F5GYU2;F5GXY2;F5GXH2;F5GZQ4;F5H5J4;F5H6W8;F5H8H6;F5GXC7;F5GWW2;F5GXU1 P00338 LDHA L-lactate dehydrogenase A chain 0 0 69.422 0.017438 20307000 1462 1040.4 1042.7 1184 1163.9 1471.8 1406.9 1341.8 1219 1342 FALSE FALSE TRUE 1346.281157 1130.32754 1081.343379 1179.100922 1150.021253 1166.532089 1446.373828 1750.908643 1085.27875 1388.6344 0.969500077 0.813984977 0.778709918 0.849108247 0.828167049 0.84005703 1.041580007 1.260885257 0.781543904 1 10.4394511 -4.37132826 3.139754427 0.929600031 1.275695985 0.56764041 0.095269375 0.192147419 3.00115031 0.014809949 0.138346374 4.25E-05 4.37132826 0.346095954 DQMEGS(ph)PNSSESFEHIAR ddPTM_HeLa_Curcumin_4h_R1 2 DQMEGSPNSSESFEHIAR 18 0 E7EPN9;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;Q9Y520-2 E7EPN9 PRRC2C Protein PRRC2C 1 0 DQMEGS(1)PNSSESFEHIAR;DQMEGS(0.978)PNS(0.021)S(0.001)ESFEHIAR ; 174.25 1.93E-06 27774000 4601.1 4130.5 4147.4 3959.9 5680.9 9360.4 6117.9 2410.9 5681.7 4111.7 TRUE FALSE FALSE 4236.91808 4487.522015 4301.106292 3943.514983 5613.158978 7418.947527 6289.551809 3145.972312 5058.431725 4254.581269 0.995848431 1.054750569 1.010935277 0.926886745 1.319321132 1.743755039 1.478301015 0.739431712 1.188937619 1 12.05480144 -5.709269537 6.59285875 0.999425771 1.365193722 0.242526517 0.243592375 0.169716576 16.05376032 0.032745348 0.065470643 1.95E-06 5.709269537 0.365767951 DQNES(ph)LDEEMFYK ddPTM_HeLa_Curcumin_4h_R1 1 DQNESLDEEMFYK 13 0 Q96AC1;Q96AC1-3;A0A0U1RRM8;H0YJ34 Q96AC1 FERMT2 Fermitin family homolog 2 1 0 DQNES(1)LDEEMFYK 101.53 0.006258 32918000 3691.5 3131.9 3522.6 3052.2 3458 4171.6 3336.2 2665.8 3145 2648.6 TRUE FALSE FALSE 3399.31388 3402.607481 3653.150655 3039.570805 3416.765608 3306.363136 3429.804793 3478.590148 2800.001368 2740.638653 1.2403364 1.241538164 1.33295597 1.109073902 1.24670416 1.206420676 1.251461877 1.269262602 1.021660176 1 11.42029641 -9.138355094 0.723591481 0.985987031 1.237789523 0.738108166 0.053702717 0.308202586 0.268986727 0.046000256 0.010910906 7.27E-10 9.138355094 0.251802492 DQNESLDEEMFY(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 DQNESLDEEMFYK 13 0 Q96AC1;Q96AC1-3;A0A0U1RRM8;H0YJ34 Q96AC1 FERMT2 Fermitin family homolog 2 1 0 DQNES(0.446)LDEEMFY(0.554)K 136.49 0.0075483 35984000 3503.5 3284 3162 3453.6 3429.1 3969.7 3736.9 2332.2 3232.8 3382.8 TRUE FALSE FALSE 3226.194278 3567.854327 3279.186502 3439.309918 3388.210222 3146.339472 3841.747357 3043.277044 2878.169928 3500.352048 0.921677087 1.019284426 0.936816199 0.982561146 0.967962701 0.898863723 1.097531706 0.869420276 0.822251559 1 11.77328431 -9.735946086 1.665695365 1.000006087 0.958380062 0 0.082420954 0.890399572 4.464935192 0.039910636 0.008662555 1.84E-10 9.735946086 -0.041626025 DQPAFTPSGILT(ph)PHALGSR ddPTM_HeLa_Curcumin_4h_R1 2 DQPAFTPSGILTPHALGSR 19 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 0 DQPAFTPS(0.001)GILT(0.999)PHALGSR;DQPAFT(0.007)PS(0.005)GILT(0.988)PHALGSR ; 143.37 0.00015622 17483800 5555.9 4327.8 4348 4571.3 6327.7 10337.3 8945.4 5913.9 5013.6 4023.6 TRUE FALSE FALSE 5116.144652 4701.875748 4509.140705 4552.385172 6252.24631 8193.227455 9196.383849 7717.020886 4463.620623 4163.419801 1.228832282 1.129330208 1.083037724 1.09342449 1.501709318 1.967908077 2.208853368 1.853529371 1.072104385 1 12.02355332 -5.442905862 2.311870467 1.108519254 2.046959947 0.943716181 0.09939856 0.053832894 0.561404659 0.01684752 0.043311597 3.61E-06 5.442905862 0.938440693 DQQEAALVDMVNDGVEDLR ddPTM_HeLa_Curcumin_4h_R1 11 DQQEAALVDMVNDGVEDLR 19 0 P09211;A8MX94 P09211 GSTP1 Glutathione S-transferase P 0 0 ;;;;;;;;;; ;;;;;;;;;; 303.44 1.98E-97 182699300 22745.27 22210.5 19733.4 20883.91 19405.86 28103.6 22219.2 22024.8 23415.3 18874.73 FALSE FALSE TRUE 20944.95788 24130.27665 20464.73716 20797.49791 19174.45779 22274.59657 22842.61095 28740.06013 20846.70017 19530.62546 1.072416135 1.235509672 1.047828048 1.064865944 0.981763632 1.140495813 1.16957908 1.471538133 1.06738518 1 14.25345053 -3.92345293 1.221136792 1.051285102 1.993306992 0.74958812 0.068306857 1.108262144 0.7965578 0.010794326 1.604248325 0.000119274 3.92345293 0.94202189 DQQNLPYGVTPAS(ph)PSGHSQGR ddPTM_HeLa_Curcumin_4h_R1 1 DQQNLPYGVTPASPSGHSQGR 21 0 E7ETY4;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E9PC69;Q7KZI7-14;Q7KZI7-6;Q7KZI7-10;Q7KZI7-12;Q7KZI7-8;Q7KZI7-11;Q7KZI7-9;Q7KZI7-3;Q7KZI7-4;Q7KZI7-5;Q7KZI7-2;Q7KZI7-7;Q7KZI7 E7ETY4 MARK2 Serine/threonine-protein kinase MARK2 1 0 DQQNLPYGVTPAS(0.958)PS(0.027)GHS(0.014)QGR 135.03 1.64E-05 14854000 1225.4 726.11 776.04 822.26 1071.1 1503.9 901.72 435.06 1116.4 897.35 TRUE FALSE FALSE 1128.408297 788.8717129 804.8007251 818.857706 1058.327832 1191.974188 927.0198363 567.7077912 993.9337131 928.5328457 1.21525943 0.849589453 0.866744487 0.881883403 1.139785024 1.283717849 0.998370538 0.611403026 1.07043463 1 9.858809134 -7.26165125 24.99999903 1.101650285 0.964037796 0.123175617 0.176674971 34.73755278 4098832.665 0.032361423 0.038256039 5.47E-08 7.26165125 -0.137612489 DQRGLT(ph)ALMKAAMR ddPTM_HeLa_Curcumin_4h_R1 1 DQRGLTALMKAAMR 14 2 Q7Z3H0-1;Q7Z3H0 Q7Z3H0-1 ANKRD33 Ankyrin repeat domain-containing protein 33 1 0 DQRGLT(1)ALMKAAMR 70.1 0.0091467 0 619.25 330.96 378.05 372.62 355.29 419.12 418.87 520.09 445.05 398.99 TRUE FALSE FALSE 570.2357091 359.5667077 392.0608656 371.0781972 351.0533988 332.1897875 430.6223649 678.6630468 396.2291285 412.8548728 1.381201353 0.87092761 0.949633616 0.898810264 0.850307025 0.804616366 1.043035685 1.643829567 0.95972981 1 8.689490923 -7.245222733 24.85146631 1.180011759 0.989610904 0.01151433 0.250961979 1344.236579 2059999.239 0.043537983 0.053231041 5.69E-08 7.245222733 -0.190400855 NIIEATHMYDNAAEACST(ph)TEEVFNSPR ddPTM_HeLa_Curcumin_4h_R1 1 NIIEATHMYDNAAEACSTTEEVFNSPR 27 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 0 NIIEATHMYDNAAEACS(0.117)T(0.459)T(0.008)EEVFNS(0.416)PR 174.89 4.08E-13 6607100 1669 1318.4 1421.2 1662.4 1651.2 1552.9 953.59 536.23 1743.5 1478.4 TRUE FALSE FALSE 1536.896889 1432.356621 1473.870922 1655.521429 1631.510518 1230.811035 980.3451689 699.7240585 1552.242412 1529.77429 1.00465598 0.936318927 0.96345646 1.082199799 1.066504078 0.80457035 0.640843015 0.457403463 1.014687214 1 10.57910309 -4.776231598 1.821205023 1.003873075 0.471075006 0.933433752 0.049791956 0.069276067 0.409389407 0.007227659 0.044791735 1.67E-05 4.776231598 -0.532798069 down DQS(ph)PFSK ddPTM_HeLa_Curcumin_4h_R1 4 DQSPFSK 7 0 Q13427;E9PG73 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 0 DQS(0.972)PFS(0.028)K;DQS(0.921)PFS(0.079)K;DQS(0.976)PFS(0.024)K;DQS(0.93)PFS(0.07)K ;;; 128.28 0.0078635 865290000 39090.5 33361.5 37750.6 35852.1 40871.2 40349.6 38300.2 32513.9 35910.3 31680.1 TRUE FALSE FALSE 35996.44568 36245.1194 39149.67044 35703.75351 40383.83763 31980.63813 39374.80053 42427.23843 31971.02993 32780.98112 1.098089333 1.105675247 1.19428001 1.089160614 1.231928889 0.975585142 1.201147714 1.294263838 0.97529204 1 15.00057141 -2.790017038 0.021156979 2.83E-07 2.469087822 0.454859245 0.078385906 1223.706215 2.802472468 130.5746033 203.8196656 0.001621746 2.790017038 2.469087539 DQT(ph)ASAPAT(ph)PLVNK ddPTM_HeLa_Curcumin_4h_R1 1 DQTASAPATPLVNK 14 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2;A0A0B4J1Z0 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 2 0 DQT(0.972)AS(0.441)APAT(0.587)PLVNK 123.42 0.0054324 16884000 7860.6 6072.7 7231.2 8330.7 7567.2 10336 9576.9 3466.6 7323.5 7148.8 TRUE FALSE FALSE 7238.425216 6597.597129 7499.194633 8296.229771 7476.966082 8192.197089 9845.602039 4523.550382 6520.130372 7397.220268 0.978533145 0.891902213 1.013785498 1.121533423 1.010780511 1.10746967 1.330986733 0.611520303 0.881429799 1 12.85276752 -6.51830046 24.76649442 0.98083312 1.056571392 0.040203165 0.173333246 467.922158 2531260.537 0.024141302 0.034652139 3.03E-07 6.51830046 0.075738272 DQT(ph)PDENDQVVVK ddPTM_HeLa_Curcumin_4h_R1 2 DQTPDENDQVVVK 13 0 O00425;O00425-2 O00425 IGF2BP3 Insulin-like growth factor 2 mRNA-binding protein 3 1 0 DQT(1)PDENDQVVVK;DQT(1)PDENDQVVVK ; 299.31 5.77E-87 45515000 5149.1 4695 4627.2 5209.4 4942.8 5393.2 4869.6 4691.8 5629.4 5004.4 TRUE FALSE FALSE 4741.543302 5100.814879 4798.688102 5187.844883 4883.860338 4274.589526 5006.22787 6122.308222 5011.868904 5178.302528 0.915655908 0.985036091 0.926691339 1.001842757 0.943139245 0.825480841 0.966770065 1.182300221 0.967859424 1 12.33826354 -4.267178542 5.543531614 0.951528472 1.189788136 0.671654715 0.049172772 0.067922446 8.162776048 0.007293857 0.060895416 5.41E-05 4.267178542 0.238259664 DQTASAPAT(ph)PLVNK ddPTM_HeLa_Curcumin_4h_R1 2 DQTASAPATPLVNK 14 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2;A0A0B4J1Z0 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 0 DQT(0.008)AS(0.01)APAT(0.982)PLVNK;DQT(0.002)AS(0.042)APAT(0.957)PLVNK ; 188 4.35E-05 49945200 7376.7 5900.1 6326.9 6938 5604.7 7062.9 7429.7 5324.53 6458.5 5201.4 TRUE FALSE FALSE 6792.826411 6410.078354 6561.38048 6909.292394 5537.867613 5597.974925 7638.157386 6947.954686 5750.018708 5382.148263 1.262103175 1.19098881 1.219100656 1.283742487 1.028932564 1.040100468 1.419165176 1.290925918 1.068350114 1 12.39396642 -9.341736559 0.933037767 0.992511561 1.216237412 0.294337677 0.111416719 0.581471349 0.857326493 0.09212082 0.021181954 4.55E-10 9.341736559 0.223725851 YHGHSMS(ph)DPGVS(ph)YR ddPTM_HeLa_Curcumin_4h_R1 1 YHGHSMSDPGVSYR 14 0 P08559-3;P08559;P08559-2;P08559-4;Q5JPU3;P29803 P08559-3 PDHA1;PDHA2 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial" 2 0 YHGHS(0.35)MS(0.65)DPGVS(0.661)Y(0.34)R 101.61 0.010984 7934500 2231.3 1165 1303.2 1756.1 1940.1 1531.3 787.15 305.46 1847.4 1300.3 TRUE FALSE FALSE 2054.690251 1265.697409 1351.497738 1748.833724 1916.965575 1213.691119 809.2353105 398.5933478 1644.744842 1345.485328 1.527099707 0.940699525 1.004468581 1.299779111 1.424739114 0.902047085 0.601444916 0.296245035 1.222417523 1 10.39391094 -4.775168968 2.039266413 1.225343954 0.33506814 0.726906401 0.185500939 0.168513638 1.29831664 0.034027113 0.189853938 1.68E-05 4.775168968 -0.890275814 down DQTS(ph)PAVK ddPTM_HeLa_Curcumin_4h_R1 1 DQTSPAVK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 DQT(0.412)S(0.588)PAVK 97.163 0.016713 21379000 5149.4 6370.6 5839.8 4027.7 5069.3 7092.7 5504.7 3546.2 4839.3 4879 TRUE FALSE FALSE 4741.819556 6921.246277 6056.228125 4011.034445 5008.851908 5621.594069 5659.147067 4627.420055 4308.440897 5048.544887 0.939244805 1.370938841 1.199598748 0.794493173 0.992137739 1.113507792 1.120946172 0.916584909 0.853402514 1 12.30165191 DQVANS(ph)AFVER ddPTM_HeLa_Curcumin_4h_R1 2 DQVANSAFVER 11 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 0 DQVANS(1)AFVER;DQVANS(1)AFVER ; 153.2 0.00047572 16271700 2135.76 1346.74 2031.8 2048.44 2311.8 2772.1 1738.12 2002.31 1950.8 1475.69 TRUE FALSE FALSE 1966.712342 1463.146205 2107.100295 2039.964098 2284.233295 2197.135212 1786.886969 2612.805101 1736.802121 1526.970118 1.287983517 0.958202251 1.379922417 1.335955481 1.495925342 1.438885533 1.170217379 1.711104279 1.137417229 1 10.57645611 -1.000033186 0.038831353 1.25E-05 3.42454486 0.461201515 0.161469303 440.5890982 1.317554261 32.74449911 101.4354446 0.099992359 1.000033186 3.424532343 DQVANSAFVER ddPTM_HeLa_Curcumin_4h_R1 3 DQVANSAFVER 11 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 ;; ;; 194.48 1.27E-11 75568000 6490.4 5469.8 5412.9 6221.8 6140.8 6823.1 5735.7 6026.3 7001.3 6406.4 FALSE FALSE TRUE 5976.677991 5942.585139 5613.506836 6196.05584 6067.574971 5407.912148 5896.628305 7863.691128 6233.274906 6629.021923 0.901592733 0.896449764 0.846807704 0.93468628 0.915304707 0.815793372 0.889517092 1.186252093 0.940300844 1 12.69458031 -9.236827123 0.986636041 0.999641746 0.915012103 0.017003313 0.096316535 1.018687599 1.790536631 0.059728524 0.016760983 5.80E-10 9.236827123 -0.084629643 DQVTAQEIFQDNHEDGPTAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 DQVTAQEIFQDNHEDGPTAKK 21 1 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 1 DQVTAQEIFQDNHEDGPTAK(1)K 176.61 1.25E-07 2553400 1400 1280.8 1311.8 1242.8 1288.1 1912 1464.8 1430.4 1337 1200.6 FALSE TRUE FALSE 1289.188523 1391.506645 1360.416462 1237.657623 1272.740249 1515.429647 1505.898346 1866.522375 1190.334445 1242.320761 1.037725975 1.120086445 1.095060555 0.99624643 1.024486018 1.219837658 1.212165484 1.502448027 0.95815387 1 10.278822 -1 0.582902081 1.024497665 27.8555473 0.87131853 0.055228905 32.47485403 0.24487521 0.009407791 1107.66894 0.1 1 26.83104964 DRAS(ph)PADLR ddPTM_HeLa_Curcumin_4h_R1 2 DRASPADLR 9 1 E5RGB3;Q9UPQ4-2;Q9UPQ4 E5RGB3 TRIM35 Tripartite motif-containing protein 35 1 0 DRAS(1)PADLR;DRAS(1)PADLR ; 76.165 0.016374 6847200 4377.4 3140.9 3665.7 3605.1 3283.6 3771.8 2129.8 1923.25 4626.3 3753.4 TRUE FALSE FALSE 4030.924171 3412.3854 3801.554067 3590.183051 3244.445215 2989.486163 2189.556456 2509.640071 4118.806464 3883.830371 1.037873384 0.878613398 0.97881568 0.924392342 0.835372533 0.769726244 0.563762123 0.64617654 1.060501122 1 11.92326448 -5.218826982 0.716809475 1.012378273 0.532982907 0.887495343 0.053179847 0.231059967 0.164568632 0.008933673 0.069290667 6.04E-06 5.218826982 -0.479395366 DRCPLPCIPTLIGT(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 2 DRCPLPCIPTLIGTPVK 17 1 Q9H0H5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 0 DRCPLPCIPTLIGT(1)PVK;DRCPLPCIPTLIGT(1)PVK ; 134.86 0.00028618 122785000 6995.6 5343.5 6608.2 6338.4 7219.8 8646.7 5515.8 2190.5 6404.8 4623.5 TRUE FALSE FALSE 6441.890878 5805.36833 6853.105705 6312.17338 7133.7086 6853.276952 5670.558503 2858.373366 5702.209464 4784.166281 1.346502295 1.213454548 1.432455584 1.319388376 1.491107997 1.432491379 1.185276215 0.597465305 1.191891989 1 12.22405182 -2.685237522 8.495882071 1.208218748 1.218180298 0 0.250855113 0 0 0.034752319 0 0.002064251 2.685237522 0.00996155 DRDDRDFDFCR ddPTM_HeLa_Curcumin_4h_R1 2 DRDDRDFDFCR 11 2 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 0 0 ; ; 73.841 0.013604 31241000 4288.2 3721 3627.4 3716.8 3865.8 4883.4 3540 2570.4 3884.6 3928 FALSE FALSE TRUE 3948.784445 4042.62666 3761.834635 3701.420866 3819.70286 3870.527793 3639.322873 3354.103127 3458.469099 4064.497708 0.971530735 0.994619003 0.925534938 0.910671166 0.939772423 0.952277027 0.895393019 0.825219589 0.850897047 1 11.98886136 -1 0.245604961 0.997199669 0.068074676 0.134578263 0.051041294 16.48157077 0.204678579 0.014497668 6.362596475 0.1 1 -0.929124993 DRDGYSYGSR ddPTM_HeLa_Curcumin_4h_R1 4 DRDGYSYGSR 10 1 Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80;Q13247-2 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 0 0 ;;; ;;; 108.31 0.0071859 22973250 4100.76 3390.39 2937.01 3118.33 3208.61 3906.06 3041.13 3346.33 3438.53 3398.703 FALSE FALSE TRUE 3776.180519 3683.440204 3045.858174 3105.427177 3170.349421 3095.899126 3126.455923 4366.610612 3061.331862 3516.807676 1.073752353 1.047381757 0.86608608 0.883024454 0.901485015 0.880315164 0.889003952 1.241640435 0.870486004 1 11.78005073 -6.783117839 24.83014503 1.036742207 0.933567898 0.003194567 0.117619009 275.9762886 316097.5616 0.01652527 0.021729334 1.65E-07 6.783117839 -0.103174309 DRDNDSDDVESNLLLPAGIALR ddPTM_HeLa_Curcumin_4h_R1 2 DRDNDSDDVESNLLLPAGIALR 22 1 Q9NZM1-8;Q9NZM1-7;Q9NZM1-5;Q9NZM1-2;Q9NZM1-6;Q9NZM1-3;Q9NZM1 Q9NZM1-8 MYOF Myoferlin 0 0 ; ; 189.98 5.33E-13 12787100 5770.1 4773.4 4910 6675.8 4816.1 6452.2 3702.7 2394.33 6988.5 6087.5 FALSE FALSE TRUE 5313.390496 5185.991426 5091.968919 6648.177308 4758.671153 5113.940989 3806.587797 3124.350195 6221.879034 6299.040172 0.843523831 0.823298675 0.808372193 1.055427038 0.755459725 0.811860355 0.604312354 0.49600417 0.987750334 1 12.6209163 -3.924511642 0.605421473 0.920635302 3.85E-14 0.723958271 0.0867099 1.95499487 0.369358233 0.01665441 1.372220426 0.000118984 3.924511642 -0.920635302 down DRDS(ph)QRDLVEAVAHILGIR ddPTM_HeLa_Curcumin_4h_R1 1 DRDSQRDLVEAVAHILGIR 19 2 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 1 0 DRDS(1)QRDLVEAVAHILGIR 48.623 0.013942 12177000 384.52 272.77 344.79 417.02 520.29 438.81 378.33 286.38 427.9 375.68 TRUE FALSE FALSE 354.0848363 296.3470234 357.5682207 415.2944817 514.0858816 347.7958596 388.9449216 373.6959437 380.9604406 388.734852 0.910864653 0.762337161 0.919825477 1.068323253 1.322458943 0.894686591 1.000540393 0.961313198 0.980000735 1 8.602642648 -6.260955062 24.99954917 0.936463382 1.053314062 0.22721783 0.120938248 62.15644407 3208375.289 0.019171805 0.030550607 5.48E-07 6.260955062 0.11685068 DRDVTFSPATIENELIK ddPTM_HeLa_Curcumin_4h_R1 1 DRDVTFSPATIENELIK 17 1 H7C2D6;P55145 H7C2D6 MANF Mesencephalic astrocyte-derived neurotrophic factor 0 0 135.57 0.00030231 2643300 1286.8 893.01 1002.6 1224.7 1019.3 1931.1 1104.1 881.17 1392.5 1043.1 FALSE FALSE TRUE 1184.948422 970.1978052 1039.757238 1219.632516 1007.145513 1530.568092 1135.078074 1149.834677 1239.746234 1079.347647 1.097837592 0.898874248 0.963320058 1.129971904 0.933105766 1.418049222 1.051633435 1.065305214 1.148606973 1 10.0759439 DRDYLFR ddPTM_HeLa_Curcumin_4h_R1 1 DRDYLFR 7 1 Q9UBK8;Q9UBK8-1 Q9UBK8 MTRR Methionine synthase reductase 0 0 113.5 0.012969 6588700 2708.7 2572 2582.6 2595 2494.3 2370.7 2214 2233.4 2049.8 2412.4 FALSE FALSE TRUE 2494.303537 2794.312219 2678.313428 2584.262578 2464.557102 1878.990097 2276.118881 2914.353379 1824.942068 2496.23072 0.999227963 1.119412639 1.07294306 1.035265914 0.987311422 0.75273094 0.911822318 1.167501607 0.731079084 1 11.28553557 -5.511462467 24.81809511 1.01767803 0.929002447 0.003044075 0.135924248 770.8959609 1675864.182 0.014395798 0.03053878 3.08E-06 5.511462467 -0.088675583 DRDYSDHPSGGSYR ddPTM_HeLa_Curcumin_4h_R1 2 DRDYSDHPSGGSYR 14 1 P38159;P38159-2;H3BUY5;Q96E39;H0Y6E7;H3BT71 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 0 0 ; ; 79.089 0.0092044 18190200 4959.4 4158.6 3126.5 3864.6 7858 17570.4 6432.9 5920.5 8326.9 3797.8 FALSE FALSE TRUE 4566.858257 4518.050854 3242.37084 3848.609309 7764.298482 13926.10098 6613.389861 7725.633195 7413.459903 3929.773267 1.162117493 1.14969759 0.825078349 0.979346402 1.975762456 3.543741594 1.682893493 1.965923393 1.886485402 1 11.94023036 -5.652490025 4.487690629 1.058082889 2.386532427 0.522190969 0.530025166 0.097534259 3.397279609 0.064470289 0.131727346 2.23E-06 5.652490025 1.328449538 DREAAEGLGSHDR ddPTM_HeLa_Curcumin_4h_R1 2 DREAAEGLGSHDR 13 1 P17655 P17655 CAPN2 Calpain-2 catalytic subunit 0 0 ; ; 110.25 0.0018449 32924000 8187.6 6822.5 7154.9 7592.3 7702.6 7658.5 5920.7 6168.6 8433.2 8245.4 FALSE FALSE TRUE 7539.54282 7412.2065 7420.066888 7560.885074 7610.751526 6070.040771 6086.818907 8049.377743 7508.099059 8531.927036 0.883685806 0.868761121 0.869682412 0.886187264 0.892031952 0.71145015 0.713416662 0.943441934 0.880000383 1 13.05865591 -8.822872595 0.185219873 1.110870472 0.762248119 0.165918603 0.077882482 4.776693191 0.349933201 0.473307673 0.166145494 1.50E-09 8.822872595 -0.348622353 DREDYVPYTGEK ddPTM_HeLa_Curcumin_4h_R1 2 DREDYVPYTGEK 12 1 Q9NYL9 Q9NYL9 TMOD3 Tropomodulin-3 0 0 ; ; 147.52 0.00061791 32817000 13769.9 13427 14437.8 13365.8 16168.4 15681.5 12461.6 12971.1 12648.7 10895.9 FALSE FALSE TRUE 12679.99789 14587.57005 14972.87757 13310.49586 15975.60239 12428.98013 12811.23896 16925.92868 11261.16926 11274.53171 1.124658496 1.293851525 1.32802656 1.180580817 1.416963719 1.102394356 1.136298986 1.501253365 0.99881481 1 13.46077989 -7.679016105 1.166182102 1.033156268 1.272239726 0.461847084 0.118844388 0.27662383 0.777987088 0.026244355 0.025562173 2.09E-08 7.679016105 0.239083459 DREEALHQFR ddPTM_HeLa_Curcumin_4h_R1 2 DREEALHQFR 10 1 A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8Y5G6;A0A2R8YFR4;A0A0D9SFB3;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;A0A0D9SF53;A0A2R8YF78;F6S8Q4;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;O15523-2;O15523;A0A0J9YVQ7;A0A2R8YDH3;A0A087WVZ1 A0A2R8YCW1 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 0 0 ; ; 102.06 0.0051761 47220900 4769.9 3877.4 3919.6 4338.4 4280.2 5175.8 4102.3 3922.2 4551.9 3683.7 FALSE FALSE TRUE 4392.357382 4212.545179 4064.863824 4320.44885 4229.16141 4102.280737 4217.399497 5118.060724 4052.567958 3811.708301 1.152333032 1.105159379 1.06641524 1.13346786 1.10951864 1.076231551 1.106432907 1.342720985 1.063189425 1 11.896222 -13.52287875 0.202213369 0.37334833 1.159144462 0.266588361 0.073451378 44.48644724 0.542937576 11.06423735 0.071158602 3.00E-14 13.52287875 0.785796132 DREEDEEDAYER ddPTM_HeLa_Curcumin_4h_R1 2 DREEDEEDAYER 12 1 P49756 P49756 RBM25 RNA-binding protein 25 0 0 ; ; 187.62 1.41E-05 38658000 6118.3 4968.8 4830.1 5236.2 4889.4 6934 5308.5 4071.2 6077.2 5365.1 FALSE FALSE TRUE 5634.030099 5398.280931 5009.107755 5214.533992 4831.097098 5495.810238 5457.442223 5312.490139 5410.546364 5551.536826 1.014859538 0.97239397 0.902292088 0.939295578 0.870226975 0.989961953 0.983050711 0.956940448 0.974603346 1 12.43867149 -7.025459345 5.071327433 1.00661621 0.940840225 0.336591372 0.034777877 0.131675417 9.243554364 0.005675877 0.00716729 9.43E-08 7.025459345 -0.065775985 DREEDEEDAYERR ddPTM_HeLa_Curcumin_4h_R1 2 DREEDEEDAYERR 13 2 P49756 P49756 RBM25 RNA-binding protein 25 0 0 ; ; 136.5 0.0004691 38799000 6236.1 5416.4 5674.1 6131.8 5688.4 7017.9 5332.6 4949.9 6563.4 6150.8 FALSE FALSE TRUE 5742.506105 5884.569481 5884.387137 6106.428236 5620.569545 5562.308432 5482.218404 6459.101723 5843.411441 6364.539842 0.902265717 0.924586793 0.924558143 0.959445363 0.883106978 0.87395296 0.86136917 1.014857615 0.918120019 1 12.6358405 -9.339170246 0.763322062 1.008098048 0.913931158 0 0.04930023 0.712841092 0.639841864 0.043168732 0.008191416 4.58E-10 9.339170246 -0.09416689 DREPYFDR ddPTM_HeLa_Curcumin_4h_R1 1 DREPYFDR 8 1 H0YIQ2;P49750-3;P49750-1;P49750;F8VU51;H0YI23 H0YIQ2 YLPM1 YLP motif-containing protein 1 0 0 129.42 0.0047359 15229000 5236.5 3745.3 3587.6 3936.5 4029.6 5037 4555.8 3952.3 4550.4 4097.8 FALSE FALSE TRUE 4822.025499 4069.027043 3720.559612 3920.211806 3981.549652 3992.269421 4683.623487 5157.338076 4051.232505 4240.198245 1.137216993 0.959631321 0.877449449 0.924535029 0.939000825 0.941528955 1.104576535 1.216296451 0.955434692 1 12.049916 -4.465907597 3.861431276 1.019491507 1.206257411 0.402836776 0.080199306 0.242492598 6.861599081 0.014159769 0.089851527 3.42E-05 4.465907597 0.186765904 DREVGIPPEQSLETAK ddPTM_HeLa_Curcumin_4h_R1 1 DREVGIPPEQSLETAK 16 1 B4DXW1;P61158 B4DXW1 ACTR3 Actin-related protein 3 0 0 135.61 0.00077092 2628100 1194.1 955.96 1071.5 1251.9 1346.8 1772.3 1035.8 1165.6 1361.7 1418.3 FALSE FALSE TRUE 1099.585725 1038.588923 1111.210733 1246.71997 1330.74029 1404.705002 1064.86176 1520.986074 1212.324917 1467.585819 0.74924799 0.707685308 0.757169167 0.849503963 0.906754666 0.957153567 0.725587387 1.036386461 0.826067478 1 10.51922915 -3.637195713 4.842593573 0.856717195 11.32540851 0.250988475 0.097528778 1008.911935 296.6576962 0.016901506 113199.3164 0.000230571 3.637195713 10.46869131 DRFGLEGDEESTMLEES(ph)VSPK ddPTM_HeLa_Curcumin_4h_R1 1 DRFGLEGDEESTMLEESVSPK 21 1 Q9Y4G6 Q9Y4G6 TLN2 Talin-2 1 0 DRFGLEGDEESTMLEES(0.865)VS(0.135)PK 111.77 7.08E-05 7022700 3188.8 2197.1 2401.2 2788.5 2754.9 3213.1 2547.6 2002.4 2820.5 2823.9 TRUE FALSE FALSE 2936.403115 2387.007534 2490.190584 2776.961926 2722.049617 2546.666841 2619.078799 2612.922542 2511.098207 2922.030315 1.004918772 0.816900332 0.85221244 0.950353565 0.931561046 0.871540185 0.89632157 0.894214728 0.85936761 1 11.51275543 -7.287583308 24.54503632 1.002322763 0.890050016 0.074300873 0.057436788 248.8094204 233592.1927 0.006247258 0.007145266 5.16E-08 7.287583308 -0.112272747 DRFGLEGDEESTMLEESVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 DRFGLEGDEESTMLEESVSPK 21 1 Q9Y4G6 Q9Y4G6 TLN2 Talin-2 1 0 DRFGLEGDEEST(0.006)MLEES(0.252)VS(0.741)PK;DRFGLEGDEEST(0.001)MLEES(0.07)VS(0.929)PK ; 78.352 0.00234 10392000 4708.9 3751.49 4355.7 4514.1 4618.7 4956.32 4210.9 2764.38 5253.7 4526.3 TRUE FALSE FALSE 4336.185596 4075.752079 4517.126074 4495.42185 4563.625019 3928.323363 4329.046521 3607.226736 4677.382254 4683.588588 0.925825468 0.870219918 0.96445834 0.959824239 0.974386399 0.838742193 0.924301193 0.770184372 0.998674876 1 12.19339864 -2.410283736 0.444240276 0.962758241 2.01E-49 0.55584413 0.047415171 12.81859993 0.471236226 0.0108104 9.355718812 0.003887911 2.410283736 -0.962758241 DRFS(ph)AEDEALSNIAR ddPTM_HeLa_Curcumin_4h_R1 2 DRFSAEDEALSNIAR 15 1 C9JSU1;Q9Y608-4;Q9Y608;Q9Y608-2;Q9Y608-5;C9JJC9;C9JC17;C9J321;C9J0U5 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 0 DRFS(1)AEDEALSNIAR;DRFS(1)AEDEALSNIAR ; 102.47 0.0013623 9889300 3242.7 3419.3 2717.6 2766.8 2978.4 3815.6 3060.2 2396.6 3238.8 2740.2 TRUE FALSE FALSE 2986.036873 3714.849056 2818.316647 2755.351715 2942.884525 3024.201549 3146.060976 3127.312307 2883.511743 2835.421746 1.053119127 1.310157496 0.993967353 0.971760804 1.037900104 1.066579091 1.109556622 1.102944319 1.016960439 1 11.46934763 -8.158987194 1.745893986 1.01363307 1.079268385 0.097370479 0.087416877 0.585062161 3.592143256 0.020744372 0.017120332 6.93E-09 8.158987194 0.065635315 DRFVGQSEGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 DRFVGQSEGKK 11 2 Q9NWH9;Q9NWH9-3;H7C3F4;H0YMM0 Q9NWH9 SLTM SAFB-like transcription modulator 0 1 ; DRFVGQSEGK(1)K;DRFVGQSEGK(1)K 93.011 0.0039502 22517000 5817.6 5501.5 5918.4 5855.9 5103.5 8289.2 5820.5 5818.4 7201.4 6336.1 FALSE TRUE FALSE 5357.130821 5977.025146 6137.74111 5831.669837 5042.644096 6569.926481 5983.807565 7592.403375 6411.424437 6556.279003 0.817099275 0.911648992 0.936162282 0.889478595 0.769132017 1.002081589 0.912683484 1.15803543 0.977905979 1 12.67866153 -3.671514302 1.519723195 0.905315237 1.960155844 0.506683811 0.071896071 4.228999222 2.498435709 0.011896577 10.45805093 0.000213052 3.671514302 1.054840606 DRPFFAGLVK ddPTM_HeLa_Curcumin_4h_R1 2 DRPFFAGLVK 10 1 Q32Q12;P22392-2;J3KPD9;E7ERL0;E5RHP0;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 0 ; ; 119.22 0.0014651 2138020 1150.17 775.51 802.62 925.44 996.63 2394.6 1346.54 1144.56 923.45 1216.17 FALSE FALSE TRUE 1059.132831 842.5416288 832.3658033 921.6107745 984.7458382 1897.932967 1384.320288 1493.531075 822.1498454 1258.431817 0.841629095 0.669517106 0.661430991 0.732348596 0.78251823 1.508173062 1.100035989 1.186819226 0.653312984 1 10.29741134 -5.279110761 24.95280637 0.860578169 1.2485121 0.644487162 0.159603111 451.3169272 637279.706 0.024304488 0.054460784 5.26E-06 5.279110761 0.38793393 DRPFFPGLVK ddPTM_HeLa_Curcumin_4h_R1 3 DRPFFPGLVK 10 1 Q32Q12;P22392-2;J3KPD9;P22392;F6XY72;O60361 Q32Q12 NME1-NME2;NME2;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase 0 0 ;; ;; 102.52 0.0040632 17493400 10463.3 6513.3 9085.6 8196.5 8123.9 10584.1 8131.9 7716.1 8287.4 7902.2 FALSE FALSE TRUE 9635.118764 7076.280629 9422.320329 8162.585055 8027.027798 8388.838353 8360.059228 10068.70337 7378.292954 8176.800862 1.178348223 0.865409437 1.152323566 0.998261446 0.981683171 1.025931595 1.022411988 1.231374414 0.902344704 1 12.99732079 QQLS(ph)PDRQPQSSGPDR ddPTM_HeLa_Curcumin_4h_R1 1 QQLSPDRQPQSSGPDR 16 1 Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;A0A1B0GUA8;Q9H1H9;H0Y307 Q9H1H9-3 KIF13A Kinesin-like protein KIF13A 1 0 QQLS(0.976)PDRQPQS(0.012)S(0.012)GPDR 154.81 0.0030013 3967000 3567.9 3860.4 4188.5 3554.9 3570.7 3567.6 1962.8 1047.1 3472.8 3460.6 TRUE FALSE FALSE 3285.49695 4194.075774 4343.729495 3540.190766 3528.121735 2827.639545 2017.870885 1366.35597 3091.842529 3580.855592 0.917517299 1.171249626 1.213042353 0.988643824 0.985273392 0.789654727 0.563516409 0.381572486 0.86343681 1 11.80608862 -4.770113268 1.55408552 1.000978668 0.364538101 0.827462939 0.100973006 0.161370658 0.642772357 0.015821539 0.116827044 1.70E-05 4.770113268 -0.636440567 down DRPMEESLLLFEAMR ddPTM_HeLa_Curcumin_4h_R1 1 DRPMEESLLLFEAMR 15 1 A0A1B0GVU9;P47897-2;P47897;B4DDN1;A0A1B0GTT3;A0A0U1RQQ5 A0A1B0GVU9 QARS Glutamine--tRNA ligase 0 0 120.66 0.0010981 5940000 700.29 525.61 456.45 554.87 666.5 783.74 796.02 365.01 828.52 713.42 FALSE FALSE TRUE 644.8613076 571.0413863 473.3664385 552.574095 658.5524228 621.1834894 818.3541788 476.2998687 737.6334289 738.2112919 0.873545711 0.773547347 0.641234351 0.748531079 0.892092047 0.841471129 1.108563616 0.645208051 0.999217212 1 9.527889995 -8.300707451 1.014756876 0.979577957 0.819127369 0.248168402 0.127324991 0.522635392 1.118206642 0.040144753 0.026707501 5.00E-09 8.300707451 -0.160450588 DRPVGGS(ph)PGGPR ddPTM_HeLa_Curcumin_4h_R1 2 DRPVGGSPGGPR 12 1 Q8NHG8 Q8NHG8 ZNRF2 E3 ubiquitin-protein ligase ZNRF2 1 0 DRPVGGS(1)PGGPR;DRPVGGS(1)PGGPR ; 73.593 0.014188 209012000 2226.64 1921.21 1983.81 1923.84 1763.8 2490.5 2038.46 1658.58 2253.67 2021.25 TRUE FALSE FALSE 2050.399094 2087.270832 2057.331744 1915.87966 1742.767837 1973.942226 2095.653701 2164.273407 2006.448039 2091.488287 0.980354089 0.997983515 0.983668786 0.916036524 0.833266841 0.943797887 1.001991603 1.034800635 0.95933984 1 11.0303142 -6.399655592 6.475704589 0.990985998 0.942845762 0.117024866 0.050924565 0.354412106 17.40594721 0.008239098 0.012611477 3.98E-07 6.399655592 -0.048140236 DRPVSQPSLVGS(ph)KEEPPPAR ddPTM_HeLa_Curcumin_4h_R1 1 DRPVSQPSLVGSKEEPPPAR 20 2 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;F6UYG0 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 0 DRPVSQPS(0.001)LVGS(0.999)KEEPPPAR 50.117 0.011024 34167000 1645.6 1513.7 1423.2 1725.2 1304.2 2313 1815.1 1366.5 1877.3 1688 TRUE FALSE FALSE 1515.349024 1644.537483 1475.945044 1718.06158 1288.648267 1833.257727 1866.026821 1783.139559 1671.364887 1746.657874 0.867570602 0.941533833 0.845010958 0.983627993 0.737779439 1.049580318 1.068341344 1.020886566 0.956893111 1 10.77038133 -5.103662304 23.19043254 0.920326433 1.048575019 0.423047228 0.074216224 15.10193922 3370.047928 0.01095676 0.027934409 7.88E-06 5.103662304 0.128248586 DRRPS(ph)VDAPVTDVGFLR ddPTM_HeLa_Curcumin_4h_R1 1 DRRPSVDAPVTDVGFLR 17 2 A0A1B0GTT1;A0A1B0GVM0;Q9BUH8;G3V536;G3V3S3 A0A1B0GTT1 BEGAIN Brain-enriched guanylate kinase-associated protein 1 0 DRRPS(1)VDAPVTDVGFLR 70.987 0.013346 97436000 2176.6 1481.5 1902.4 1781.7 1727.2 1986.7 1402.8 1093.3 1977.6 1734.9 TRUE FALSE FALSE 2004.319813 1609.554259 1972.904618 1774.327797 1706.604268 1574.636025 1442.158793 1426.642137 1760.662228 1795.187646 1.116495993 0.896593881 1.098996321 0.988380129 0.950655087 0.87714286 0.803347102 0.794703629 0.980767794 1 10.80991894 -5.255663615 0.951959873 1.047182962 0.770796373 0.652659431 0.061423325 0.297093792 0.435974122 0.01034 0.058944367 5.55E-06 5.255663615 -0.276386589 DRS(ph)SPPPGYIPDELHQVAR ddPTM_HeLa_Curcumin_4h_R1 4 DRSSPPPGYIPDELHQVAR 19 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 0 DRS(0.5)S(0.5)PPPGYIPDELHQVAR;DRS(0.5)S(0.5)PPPGYIPDELHQVAR;DRS(0.494)S(0.494)PPPGY(0.011)IPDELHQVAR;DRS(0.5)S(0.5)PPPGYIPDELHQVAR ;;; 145.67 4.95E-05 224451500 12526.3 10109.5 11215.4 11518 10197.4 12198.1 9182.8 8710 13273.6 11505.9 TRUE FALSE FALSE 11534.83014 10983.32013 11631.05259 11470.34157 10075.80267 9668.076559 9440.444654 11365.6389 11817.51929 11905.72917 0.968847013 0.922523936 0.976929042 0.963430413 0.846298662 0.812052452 0.792932925 0.954636104 0.992590972 1 13.53936836 -5.784128935 4.78200654 0.978204546 0.843575263 0.630158967 0.044493558 0.083135624 4.689298217 0.006421115 0.012289746 1.64E-06 5.784128935 -0.134629283 DRS(ph)SSAPNVHINTIEPVNIDDLIR ddPTM_HeLa_Curcumin_4h_R1 2 DRSSSAPNVHINTIEPVNIDDLIR 24 1 H7C560;A0A2U3TZI2;A0A2R8Y8E0;P15056;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y679 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 0 DRS(0.333)S(0.333)S(0.333)APNVHINTIEPVNIDDLIR;DRS(0.333)S(0.333)S(0.333)APNVHINTIEPVNIDDLIR ; 68.406 0.0004428 11741400 2827.07 2481.53 2481.04 2385.71 2738.1 3715.2 2302.01 2163.46 3289.3 2684.83 TRUE FALSE FALSE 2603.304426 2696.022396 2572.989525 2375.838564 2705.449946 2944.625641 2366.598205 2823.088995 2928.472019 2778.127643 0.937071568 0.970445833 0.926159578 0.85519417 0.973839324 1.059931731 0.85186806 1.016184048 1.05411716 1 11.43989717 -9.298515237 0.896884828 1.001832717 0.946352116 0.166497307 0.063283953 1.222698453 1.668851594 0.046480667 0.010929856 5.03E-10 9.298515237 -0.055480601 SVSSPTSSNT(ph)PTPTK ddPTM_HeLa_Curcumin_4h_R1 2 SVSSPTSSNTPTPTK 15 0 Q5M775-4;Q5M775;Q5M775-5;Q5M775-3;Q5M775-2 Q5M775-4 SPECC1 Cytospin-B 1 0 SVS(0.001)S(0.033)PT(0.343)S(0.014)S(0.035)NT(0.571)PT(0.002)PT(0.001)K;SVS(0.002)S(0.009)PT(0.005)S(0.003)S(0.109)NT(0.638)PT(0.077)PT(0.156)K ; 140.93 0.0015399 27916000 9462.5 7594.9 8319.5 9667.3 9546.3 7598.4 4365 1821.08 10479.1 6719.1 TRUE FALSE FALSE 8713.53314 8251.369314 8627.827989 9627.299274 9432.466607 6022.406188 4487.470152 2376.318909 9329.568947 6952.588225 1.253279046 1.186805409 1.240951961 1.384707243 1.356684202 0.866210682 0.645438793 0.341789105 1.341884295 1 12.76333443 -4.76891028 2.031278448 1.169533489 0.387402328 0.832216259 0.135104736 0.127262643 0.969381156 0.02232295 0.126357655 1.70E-05 4.76891028 -0.782131162 down DRT(ph)PPHLLYSDRDR ddPTM_HeLa_Curcumin_4h_R1 1 DRTPPHLLYSDRDR 14 2 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 0 DRT(1)PPHLLYSDRDR 65.563 0.017277 42673000 546.68 464.96 517.56 590.14 567.73 521.99 536.7 362.47 530.19 567.75 TRUE FALSE FALSE 503.4097011 505.1490706 536.7412289 587.698157 560.9601905 413.72339 551.7583575 472.9854344 472.0294835 587.4792702 0.856897812 0.859858545 0.913634329 1.000372586 0.954859548 0.704234874 0.939196301 0.805109999 0.803482791 1 9.198394135 -13.52287873 0.285403707 1.971710228 0.870354409 0 0.101232329 50.21614872 0.678548439 27.84371577 0.036103796 3.00E-14 13.52287873 -1.101355819 DRYDSFIELQEK ddPTM_HeLa_Curcumin_4h_R1 2 DRYDSFIELQEK 12 1 Q9NSD9-2;Q9NSD9 Q9NSD9-2 FARSB Phenylalanine--tRNA ligase beta subunit 0 0 ; ; 215.34 2.95E-13 15266300 7349.9 6485.6 6487.8 6000 6965.9 7649.3 5722.5 5660.4 6762.4 6487.5 FALSE FALSE TRUE 6768.147659 7046.186365 6728.243575 5975.17359 6882.836192 6062.748955 5883.057949 7386.229903 6020.581639 6712.940142 1.008224044 1.049642365 1.002279692 0.89009785 1.025308739 0.903143604 0.87637575 1.100297298 0.896862107 1 12.71272906 -6.486286337 24.65933143 1.008306721 0.954143757 0.020278879 0.073057248 691.5347752 466019.4825 0.00899716 0.013739869 3.26E-07 6.486286337 -0.054162964 DRYSAGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 DRYSAGKR 8 2 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 1 ; DRYSAGK(1)R;DRYSAGK(1)R 88.177 0.0061896 3915900 1510.21 1009.99 1377.34 742.02 928.85 1311.04 692.6 579.19 1148.87 1270.33 FALSE TRUE FALSE 1390.675285 1097.289035 1428.385432 738.9497178 917.7740704 1039.115526 712.032492 755.7823647 1022.841835 1314.473873 1.057971036 0.834774321 1.086659432 0.562163869 0.6982064 0.790518204 0.541686302 0.574969484 0.778137821 1 10.36026975 -6.262043912 24.99999983 1.014603508 0.640724642 0.621658963 0.118990354 17.59610883 727677.4054 0.014051905 0.022281979 5.47E-07 6.262043912 -0.373878866 DS(ph)DGVDGFEAEGK ddPTM_HeLa_Curcumin_4h_R1 2 DSDGVDGFEAEGK 13 0 Q96KR1 Q96KR1 ZFR Zinc finger RNA-binding protein 1 0 DS(1)DGVDGFEAEGK;DS(1)DGVDGFEAEGK ; 262.37 1.60E-46 32855000 8340.5 7215.4 7502.7 6918.4 9337.1 9441.3 10328.7 9979.2 7277.6 6544.5 TRUE FALSE FALSE 7680.340624 7839.067025 7780.756662 6889.773494 9225.761181 7483.067955 10618.49552 13021.81214 6479.265488 6771.920888 1.13414506 1.157583964 1.148973355 1.017403128 1.362355133 1.105014084 1.568018248 1.922912621 0.95678399 1 12.7253494 -1.00000001 0.579468387 1.069902912 49.78662643 0.859213486 0.107493118 32.28637183 0.246134338 0.017758006 1985.653878 0.099999998 1.00000001 48.71672352 DS(ph)FDNCSLGESSK ddPTM_HeLa_Curcumin_4h_R1 2 DSFDNCSLGESSK 13 0 Q5UIP0-2;Q5UIP0 Q5UIP0-2 RIF1 Telomere-associated protein RIF1 1 0 DS(0.998)FDNCS(0.002)LGESSK;DS(0.97)FDNCS(0.03)LGESSK ; 153.41 0.00043442 28609000 5458.1 4719.7 4902.5 4986 5478.7 10413.2 10750.3 4194.4 6116.2 5614.6 TRUE FALSE FALSE 5026.085626 5127.649837 5084.190963 4965.369253 5413.370081 8253.384939 11051.92449 5473.253251 5445.268162 5809.706932 0.865118617 0.88260043 0.87512004 0.854667767 0.931780233 1.420619841 1.902320481 0.942087667 0.937270714 1 12.50424967 -5.246930875 5.374728252 0.918896184 1.475514578 0.531237863 0.220194645 0.088508179 8.638556847 0.028069032 0.070043696 5.66E-06 5.246930875 0.556618394 DS(ph)GAIAAGHQPLSTMTVRS(ph)RVADVFGS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 DSGAIAAGHQPLSTMTVRSRVADVFGSK 28 2 Q8IYM0-2;Q8IYM0 Q8IYM0-2 FAM186B Protein FAM186B 3 0 DS(0.994)GAIAAGHQPLS(0.059)T(0.059)MT(0.175)VRS(0.73)RVADVFGS(0.983)K 45.205 0.0069448 0 1024.5 601.32 1122.3 1008.6 1000.8 1421.9 991.33 1114.8 1245.5 1012.2 TRUE FALSE FALSE 943.409744 653.2954214 1163.893425 1004.42668 988.8661136 1126.981912 1019.144052 1454.697388 1108.871766 1047.373875 0.900738282 0.623746149 1.111249243 0.958995355 0.944138609 1.076007278 0.973047043 1.388899822 1.058716274 1 10.03256081 -1.389180742 1.018285254 0.940552917 199.9994103 0.494097086 0.129142953 448.4973653 1.315532032 0.018213749 207379.181 0.040814949 1.389180742 199.0588574 DS(ph)GDENEPIQER ddPTM_HeLa_Curcumin_4h_R1 2 DSGDENEPIQER 12 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;Q8WX93-4;Q8WX93-7 Q8WX93-3 PALLD Palladin 1 0 DS(1)GDENEPIQER;DS(1)GDENEPIQER ; 153 2.51E-05 2895200 872.3 1167.73 1177.55 779.76 1025.2 1261.34 1002.09 841.26 1082.12 924.02 TRUE FALSE FALSE 803.2565346 1268.663378 1221.191039 776.5335597 1012.97516 999.7238658 1030.205948 1097.756301 963.4141433 956.1296262 0.840112588 1.326873829 1.277223303 0.812163475 1.059453794 1.045594487 1.077475188 1.148124973 1.007618755 1 9.901062413 -7.304776007 24.97669642 0.924497612 1.096640178 0.203949675 0.139025874 495.225546 285417.9258 0.024874767 0.028445471 4.96E-08 7.304776007 0.172142566 INS(ph)LLEYSR ddPTM_HeLa_Curcumin_4h_R1 1 INSLLEYSR 9 0 Q6P4F7-3;Q6P4F7 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 0 INS(0.998)LLEYS(0.002)R 108.68 0.0095748 2581000 1254.3 1041.2 1054.6 1274.8 1285.5 1461.4 1663.3 1848.6 1278.5 1066.5 TRUE FALSE FALSE 1155.020831 1131.196689 1093.684404 1269.525215 1270.171252 1158.289167 1709.967721 2412.22963 1138.251749 1103.560796 1.046630902 1.025042474 0.991050432 1.15038992 1.150975331 1.049592529 1.549500243 2.185860208 1.031435471 1 10.1079504 -4.330979641 1.598671257 1.034296616 2.526009385 0.971488846 0.060516748 0.098818467 0.262237717 0.008920386 0.218750148 4.67E-05 4.330979641 1.491712768 up S(ph)LPAS(ph)PSTSDFCQTR ddPTM_HeLa_Curcumin_4h_R1 2 SLPASPSTSDFCQTR 15 0 Q9Y2D8-2;Q9Y2D8-3;Q9Y2D8;S4R2Y6 Q9Y2D8-2 SSX2IP Afadin- and alpha-actinin-binding protein 2 0 S(1)LPAS(0.963)PS(0.029)T(0.006)S(0.001)DFCQTR;S(1)LPAS(0.941)PS(0.006)T(0.022)S(0.031)DFCQTR ; 149.31 0.0010757 24114000 5334.1 4357.3 4174.3 4114.3 4802.7 5015.8 1773.27 956.27 4713.9 4184 TRUE FALSE FALSE 4911.900356 4733.925596 4329.00323 4097.276117 4745.430939 3975.46654 1823.023184 1247.832321 4196.796964 4329.393689 1.134546939 1.093438467 0.999909812 0.946385663 1.096095962 0.918250181 0.421080483 0.288223343 0.969372911 1 12.07994928 -4.76880041 2.752584195 1.055022618 0.299923119 0.95314926 0.059672701 0.040213111 0.5992339 0.009478838 0.042396221 1.70E-05 4.76880041 -0.755099499 down ANS(ph)PSLFGTEGKPK ddPTM_HeLa_Curcumin_4h_R1 1 ANSPSLFGTEGKPK 14 1 Q5JPT2;Q96B97-2;Q96B97;Q96B97-3 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 0 ANS(0.514)PS(0.486)LFGTEGKPK 130.95 0.010134 58417000 1563.4 1169.5 1269.7 1357.3 1098.3 1045.4 575.86 407.69 1480.5 1520 TRUE FALSE FALSE 1439.65524 1270.586369 1316.756199 1351.683852 1085.20349 828.5722559 592.0170818 531.9928042 1318.092854 1572.819887 0.915333823 0.807839715 0.837194526 0.859401552 0.689973149 0.526806828 0.376404881 0.338241402 0.838044372 1 10.61913775 -4.762552543 0.457559499 0.973263696 3.01E-18 0.918516231 0.062107243 0.428297645 0.080943846 0.012094818 0.207043555 1.73E-05 4.762552543 -0.973263696 down DS(ph)LGTYSSR ddPTM_HeLa_Curcumin_4h_R1 2 DSLGTYSSR 9 0 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 DS(0.856)LGT(0.143)YSSR;DS(0.998)LGT(0.002)YSSR ; 163.84 0.00041497 169922000 5765.1 5946.6 6490.3 6077.8 7154.9 7508.7 6624.9 2261.18 5826.5 5231.4 TRUE FALSE FALSE 5308.786252 6460.597606 6730.836227 6052.651674 7069.582491 5951.31098 6810.776864 2950.603373 5187.347527 5413.190761 0.980712945 1.193491582 1.243413825 1.118130127 1.305991753 1.099409063 1.258181573 0.545076555 0.958279092 1 12.40226351 -7.277285658 23.75069857 0.990892214 1.127546529 0.073601583 0.202010901 735.7869163 1102808.35 0.03189494 0.036552159 5.28E-08 7.277285658 0.136654315 (ac)S(ph)VELEEALPVTTAEGMAK ddPTM_HeLa_Curcumin_4h_R1 2 SVELEEALPVTTAEGMAK 18 0 Q92522 Q92522 H1FX Histone H1x 1 0 S(1)VELEEALPVTTAEGMAK;S(1)VELEEALPVTTAEGMAK ; 112.08 5.04E-05 6774800 3549.3 2754.4 2916.6 3230.1 3157.5 3854.8 4604.2 5877.7 4302.5 3334.2 TRUE FALSE FALSE 3268.36916 2992.478063 3024.691762 3216.734702 3119.848875 3055.271027 4733.38146 7669.783672 3830.526514 3450.063202 0.947336025 0.867369056 0.876706189 0.93236979 0.904287456 0.885569582 1.371969493 2.223084977 1.110277201 1 11.75240708 -4.329593738 2.2715605 0.946711368 2.439078015 0.965374064 0.074050781 0.053704475 0.357373121 0.009001306 0.149837066 4.68E-05 4.329593738 1.492366647 up DS(ph)QDVMAS(ph)LAR ddPTM_HeLa_Curcumin_4h_R1 1 DSQDVMASLAR 11 0 P38570 P38570 ITGAE Integrin alpha-E;Integrin alpha-E light chain;Integrin alpha-E heavy chain 2 0 DS(1)QDVMAS(1)LAR 95.183 0.016905 2876700 1719.8 1135.1 1621.4 1742.4 1544.2 1265.2 830.01 846.48 1654.5 1407.6 TRUE FALSE FALSE 1583.676015 1233.212986 1681.49051 1735.19041 1525.786424 1002.783258 853.2978467 1104.567855 1473.005489 1456.513995 1.087305732 0.846688044 1.154462309 1.191331093 1.047560428 0.688481718 0.585849398 0.758364052 1.011322579 1 10.50830385 -5.251879882 6.177249713 1.048049392 0.666049545 0.756805393 0.096311291 0.05534722 9.727792603 0.013661976 0.03360065 5.60E-06 5.251879882 -0.381999846 DS(ph)YVGDEAQSK ddPTM_HeLa_Curcumin_4h_R1 2 DSYVGDEAQSK 11 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle" 1 0 DS(1)YVGDEAQSK;DS(0.998)YVGDEAQS(0.002)K ; 143.56 0.0011156 33494000 5091.8 3964.8 4987.3 4438.3 5473.7 5346.6 3732.1 2497.9 3921.7 3587.5 TRUE FALSE FALSE 4688.778657 4307.499645 5172.133725 4419.935491 5408.429702 4237.654891 3836.812682 3259.498211 3491.499322 3712.165358 1.263084536 1.16037386 1.393292924 1.19066234 1.45694741 1.141558762 1.033578063 0.878058464 0.940555979 1 11.85804526 -4.520707526 2.526234528 1.177977758 0.879986999 0.312894081 0.148680853 0.347241764 3.823197284 0.022159992 0.171819065 3.02E-05 4.520707526 -0.297990759 DS(ph)YVGDEAQSKR ddPTM_HeLa_Curcumin_4h_R1 1 DSYVGDEAQSKR 12 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle" 1 0 DS(1)YVGDEAQSKR 160.46 2.82E-09 0 1741.3 1514.6 1625.4 1791.9 1835.1 1808.9 1344.3 723.78 1751.3 1678.9 TRUE FALSE FALSE 1603.474268 1645.515275 1685.638754 1784.485593 1813.217631 1433.713749 1382.01744 944.4571901 1559.186772 1737.24165 0.923000129 0.947199991 0.970296075 1.027194802 1.043733686 0.825281704 0.795524008 0.54365332 0.897507132 1 10.76258273 -4.339518552 1.26976769 0.970326261 0.402897953 0.860378733 0.052572242 0.314248102 0.471454771 0.007740301 0.222617069 4.58E-05 4.339518552 -0.567428307 DS(ph)YYVYTQQELK ddPTM_HeLa_Curcumin_4h_R1 1 DSYYVYTQQELK 12 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 0 DS(1)YYVYTQQELK 130.66 0.0016162 0 749.66 788.04 737.21 700.8 886.4 1007.3 809.3 644.28 625.5 697.2 TRUE FALSE FALSE 690.32362 856.1546662 764.5316511 697.9002753 875.8302589 798.3746254 832.0067799 840.7180061 556.8842149 721.4276481 0.95688545 1.186750561 1.059748199 0.967387758 1.214023695 1.106659313 1.153278201 1.165353183 0.771919702 1 9.494710904 -6.392842797 0.569116337 0.97867117 1.164451371 0.429314038 0.097779948 0.584293546 0.373793586 0.019011797 0.046717673 4.05E-07 6.392842797 0.185780201 GSEGYLAATYPTVGQTS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 GSEGYLAATYPTVGQTSPR 19 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 0 GSEGYLAAT(0.002)Y(0.006)PT(0.029)VGQT(0.004)S(0.96)PR;GSEGYLAAT(0.002)Y(0.002)PT(0.111)VGQT(0.392)S(0.494)PR ; 115.2 0.00030384 180786000 8697.8 8392.3 8958.4 9838.3 8689.7 8105.6 5650 2647.6 9344.3 9531 TRUE FALSE FALSE 8009.359952 9117.693017 9290.406185 9797.591721 8586.081003 6424.407191 5808.523794 3454.841052 8319.253668 9862.201541 0.81212698 0.924508892 0.94202153 0.993448743 0.870604902 0.651417147 0.588968271 0.350311342 0.843549347 1 13.26769402 -4.762337877 1.197513035 0.919621943 0.326403151 0.889545197 0.065540874 0.209338245 0.421518556 0.012379057 0.123127312 1.73E-05 4.762337877 -0.593218792 down SPSPIS(ph)ISSSETSSIMQK ddPTM_HeLa_Curcumin_4h_R1 1 SPSPISISSSETSSIMQK 18 0 Q5VT06 Q5VT06 CEP350 Centrosome-associated protein 350 1 0 S(0.003)PS(0.065)PIS(0.924)IS(0.006)S(0.002)SETSSIMQK 133.28 0.00011859 0 696.69 474.86 709.35 739.31 539.86 512.37 263.47 47.237 582.07 618.33 TRUE FALSE FALSE 641.5462514 515.9047825 735.639135 736.2509311 533.4225221 406.0986864 270.8622591 61.63934385 518.2183773 639.8169215 1.002702851 0.806331882 1.14976505 1.150721255 0.833711182 0.634710763 0.423343382 0.096339034 0.809947908 1 9.321515338 -4.760344532 1.177202952 1.006219413 0.031992516 0.856125834 0.119417427 0.164973186 0.317052905 0.015518916 0.157847926 1.74E-05 4.760344532 -0.974226897 down TQTPPVSPAPQPTEERLPS(ph)S(ph)PVYEDAASFK ddPTM_HeLa_Curcumin_4h_R1 1 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 2 0 T(0.002)QT(0.008)PPVS(0.067)PAPQPT(0.49)EERLPS(0.57)S(0.57)PVY(0.277)EDAAS(0.015)FK 53.184 0.0039302 44147000 4656.2 3489.7 3875 3768 3876.4 5296.8 5642.6 6727.7 4940.9 3865.3 TRUE FALSE FALSE 4287.656857 3791.334118 4018.610909 3752.409014 3830.176462 4198.183973 5800.91617 8778.944759 4398.895632 3999.618887 1.072016354 0.947923846 1.004748458 0.938191643 0.957635357 1.049646002 1.450367231 2.19494532 1.099828698 1 11.96564682 -4.322956296 1.882846281 1.012473165 2.476786927 0.980469791 0.051584129 0.068279857 0.273522551 0.007791372 0.16687572 4.75E-05 4.322956296 1.464313762 up ALSSGGSITSPPLS(ph)PALPK ddPTM_HeLa_Curcumin_4h_R1 1 ALSSGGSITSPPLSPALPK 19 0 Q6Y7W6-4;Q6Y7W6-5;Q6Y7W6;I1E4Y6;Q6Y7W6-3;E7ESB6;C9JHW1;C9JW88;F8WCD5;C9JPV7;C9JXQ0;C9J0V6;C9JHT0;C9JRZ2 Q6Y7W6-4 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 0 ALSSGGSITSPPLS(1)PALPK 175.26 1.27E-06 12534000 1259.6 1329.6 1136.8 1114.4 1177.4 1517.5 1715.2 2113.6 1584 1124.5 TRUE FALSE FALSE 1159.901331 1444.524699 1178.930808 1109.788908 1163.360274 1202.753394 1763.323896 2758.02691 1410.239163 1163.576291 0.996841668 1.241452503 1.013195969 0.953774081 0.999814351 1.033669561 1.515434707 2.370301742 1.211986849 1 10.18435009 -4.32178341 1.897891315 1.012839906 2.693209186 0.941094138 0.100192977 0.085660763 0.349713676 0.011329947 0.241729994 4.77E-05 4.32178341 1.680369281 up LMET(ph)QQEEET(ph)EKK ddPTM_HeLa_Curcumin_4h_R1 1 LMETQQEEETEKK 13 1 Q13370-2;Q13370 Q13370-2 PDE3B "cGMP-inhibited 3,5-cyclic phosphodiesterase B" 2 0 LMET(1)QQEEET(1)EKK 56.258 0.0091178 0 640.04 563.5 776.84 761.38 614.44 599.57 883.62 1206.2 734.06 729.65 TRUE FALSE FALSE 589.3801586 612.2064291 805.6303738 758.2296113 607.1132043 475.2124235 908.4119991 1573.964827 653.5354545 755.0052832 0.780630509 0.810863768 1.067052631 1.004270603 0.804117823 0.629416024 1.203186281 2.084707038 0.865603816 1 9.56034293 -4.319373056 3.068665011 0.887413368 2.198044281 0.893079105 0.126380013 0.076110372 1.11428623 0.019256836 0.222553287 4.79E-05 4.319373056 1.310630912 up DSALAEAPEGLS(ph)PAPPAR ddPTM_HeLa_Curcumin_4h_R1 3 DSALAEAPEGLSPAPPAR 18 0 C9JPC9;Q9H9J4-2;Q9H9J4 C9JPC9 USP42 Ubiquitin carboxyl-terminal hydrolase 42 1 0 DSALAEAPEGLS(1)PAPPAR;DSALAEAPEGLS(1)PAPPAR;DSALAEAPEGLS(1)PAPPAR ;; 274.68 5.98E-67 311038000 16589.2 13860.41 13550.4 14569.5 15330.2 15882.5 12827.3 8704.07 15392.2 12907 TRUE FALSE FALSE 15276.14732 15058.44208 14052.58974 14509.21527 15147.39738 12588.29047 13187.19952 11357.90087 13703.71417 13355.51729 1.143807985 1.127507213 1.052193595 1.086383624 1.134167779 0.942553568 0.987397136 0.850427627 1.026071389 1 13.70514824 -4.633091989 1.240175953 1.077242871 0.841219303 0.622172598 0.054754871 0.49812727 0.987297743 0.009868261 0.126044787 2.33E-05 4.633091989 -0.236023568 DSAPS(ph)TPTSPTEFLTPGLR ddPTM_HeLa_Curcumin_4h_R1 1 DSAPSTPTSPTEFLTPGLR 19 0 Q9NZJ4-2;Q9NZJ4 Q9NZJ4-2 SACS Sacsin 1 0 DSAPS(0.884)T(0.095)PT(0.02)SPTEFLTPGLR 160.38 1.98E-05 13737000 2453.1 1602.5 1877.1 2487.1 1876 2445.3 2887.3 2905.9 2461.6 2244.3 TRUE FALSE FALSE 2258.934547 1741.012959 1946.666977 2476.809039 1853.629925 1938.117216 2968.309867 3791.895533 2191.568639 2322.289258 0.972718854 0.749696858 0.838253448 1.066537698 0.798190802 0.834571839 1.278182663 1.63282654 0.943710449 1 11.18133197 -4.494863831 3.087461366 0.943736793 1.618151358 0.83253632 0.103670618 0.087712465 1.538800982 0.015710673 0.10804885 3.20E-05 4.494863831 0.674414565 DSAPSTPTS(ph)PTEFLTPGLR ddPTM_HeLa_Curcumin_4h_R1 1 DSAPSTPTSPTEFLTPGLR 19 0 Q9NZJ4-2;Q9NZJ4 Q9NZJ4-2 SACS Sacsin 1 0 DS(0.002)APS(0.005)T(0.037)PT(0.063)S(0.83)PT(0.063)EFLTPGLR 114.58 0.00032424 25391000 953.76 625.35 996.87 1033.6 681.83 1042.8 1378.6 1264.2 889.58 1138.2 TRUE FALSE FALSE 878.2688896 679.4024675 1033.814879 1029.323237 673.6996226 826.5115252 1417.279806 1649.64876 791.9952996 1177.752365 0.745716091 0.576863598 0.87778629 0.873972549 0.572021456 0.70177021 1.203376743 1.400675396 0.672463349 1 10.20182051 -4.613846623 4.453510322 0.824321612 1.359164439 0.685381372 0.144824603 0.10267297 3.540095559 0.023075657 0.097013114 2.43E-05 4.613846623 0.534842827 DSAQTSVTQAQR ddPTM_HeLa_Curcumin_4h_R1 2 DSAQTSVTQAQR 12 0 A0A087WY61;Q14980-2;Q14980;Q14980-4;Q14980-3;F5H6Y5;F5H4J1 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 0 0 ; ; 160.18 1.24E-05 839200 184.91 0 0 0 0 0 0 0 74.151 0 FALSE FALSE TRUE 170.2741784 0 0 0 0 0 0 0 66.01682082 0 0 DSASFNPELLTHILDGS(ph)PEKTR ddPTM_HeLa_Curcumin_4h_R1 1 DSASFNPELLTHILDGSPEKTR 22 1 I3L2U4;K7ELT1;I3L0T4;Q15067-2;Q15067 I3L2U4 ACOX1 Peroxisomal acyl-coenzyme A oxidase 1 1 0 DSASFNPELLTHILDGS(0.927)PEKT(0.073)R 103.86 2.20E-05 7021400 1233.7 930.3 1141.2 1186.1 942.43 1217.7 846.66 622.14 1159.6 1109.9 TRUE FALSE FALSE 1136.051343 1010.710987 1183.493876 1181.192232 931.1921378 965.1352937 870.4150009 811.827622 1032.394781 1148.468942 0.989187693 0.880050778 1.030497066 1.028492969 0.810811772 0.840366908 0.757891632 0.706878168 0.898931389 1 10.16549613 -5.391589479 1.328227383 0.990664711 0.735076706 0.693386125 0.060802 0.149424058 0.493195635 0.00801171 0.028955018 4.06E-06 5.391589479 -0.255588005 DSAYISS(ph)SPLGSHQVFDFR ddPTM_HeLa_Curcumin_4h_R1 2 DSAYISSSPLGSHQVFDFR 19 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 0 DSAYISS(0.596)S(0.404)PLGSHQVFDFR;DS(0.001)AYIS(0.009)S(0.542)S(0.444)PLGS(0.004)HQVFDFR ; 188.27 4.26E-09 90666000 6329.1 5253.8 5673.1 5439.1 6940.2 8609.7 5618.9 3597.7 6502.9 5428.4 TRUE FALSE FALSE 5828.145057 5707.915062 5883.350077 5416.594445 6857.442648 6823.951169 5776.551212 4694.622168 5789.548139 5617.036496 1.037583619 1.016179095 1.047411759 0.964315338 1.220829285 1.214866803 1.028398376 0.835782743 1.030712217 1 12.45559346 DSCIS(ph)PSEPETK ddPTM_HeLa_Curcumin_4h_R1 2 DSCISPSEPETK 12 0 Q8TDB6 Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L 1 0 DSCIS(0.921)PS(0.079)EPETK;DS(0.002)CIS(0.997)PS(0.001)EPETK ; 106.79 0.0065354 20271200 9211.2 7809 7844.1 8568.6 8037 10299.7 7475.4 7467.9 9599.8 8782.8 TRUE FALSE FALSE 8482.1238 8483.975164 8134.809246 8533.145404 7941.164024 8163.426118 7685.139605 9744.828332 8546.725958 9088.001646 0.933332115 0.93353583 0.895115292 0.938946287 0.873807503 0.898264155 0.845635807 1.07227405 0.940440626 1 13.14974738 -8.679517648 0.586554561 1.002539153 0.9153336 0.049536277 0.059904111 0.939673478 0.621233873 0.040239069 0.013604702 2.09E-09 8.679517648 -0.087205553 DSCPLDCK ddPTM_HeLa_Curcumin_4h_R1 2 DSCPLDCK 8 0 P84103;P84103-2;A0A087X2D0 P84103 SRSF3 Serine/arginine-rich splicing factor 3 0 0 ; ; 131.03 0.0015627 12568600 12664.4 10416.6 10714.8 11325.3 10435.9 14606.2 10130.2 9444.5 13059.9 11179.5 FALSE FALSE TRUE 11661.99938 11316.96449 11111.89991 11278.43891 10311.45871 11576.70947 10414.42615 12324.08457 11627.26164 11567.98679 1.008126962 0.97830026 0.960573358 0.974969899 0.891378845 1.000754036 0.900279913 1.065361224 1.005124042 1 13.49785019 -7.04817762 2.904209425 1.00384639 0.961263818 0.119713919 0.046089532 0.341718594 5.734431921 0.006954016 0.008868282 8.95E-08 7.04817762 -0.042582572 DSDAGSS(ph)TPTTSTR ddPTM_HeLa_Curcumin_4h_R1 2 DSDAGSSTPTTSTR 14 0 P51532;P51532-4;P51532-3;P51532-2;P51532-5;A0A0A0MT49;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8Y440;A0A2R8Y4C5;A0A2R8Y6N0;A0A2R8YG32;A0A2R8Y7F3;A0A2R8YF80;A0A2R8YF58;A0A2R8Y526;A0A2R8Y7Y7;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;K7EP28 P51532 SMARCA4 Transcription activator BRG1 1 0 DSDAGS(0.092)S(0.574)T(0.315)PT(0.019)TSTR;DSDAGS(0.084)S(0.579)T(0.327)PT(0.008)T(0.002)STR ; 211.82 6.27E-10 185177000 9810.8 8463.6 8205.2 9022.2 9097.8 9982.9 9035.5 3461.2 10419.5 8800.7 TRUE FALSE FALSE 9034.264828 9195.155871 8509.29193 8984.868527 8989.314677 7912.33401 9289.011812 4516.503947 9276.506918 9106.52367 0.992065156 1.009732825 0.934417154 0.98664088 0.987129118 0.868864376 1.020039276 0.495963565 1.018666096 1 13.15268471 -4.258900284 24.99994286 0.984407137 0.495963393 0.916195023 0.043872582 42.82073244 421587.8305 0.00567951 0.051748133 5.51E-05 4.258900284 -0.488443745 DSDAGSSTPTTSTR ddPTM_HeLa_Curcumin_4h_R1 2 DSDAGSSTPTTSTR 14 0 P51532;P51532-4;P51532-3;P51532-2;P51532-5;A0A0A0MT49;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8Y440;A0A2R8Y4C5;A0A2R8Y6N0;A0A2R8YG32;A0A2R8Y7F3;A0A2R8YF80;A0A2R8YF58;A0A2R8Y526;A0A2R8Y7Y7;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;K7EP28 P51532 SMARCA4 Transcription activator BRG1 0 0 ; ; 145.23 0.00051691 381770 0 0 113.66 0 0 57.32 54.21 0 60.709 0 FALSE FALSE TRUE 0 0 117.8723396 0 0 45.43118587 55.7309867 0 54.04937459 0 0 DSDLSHVQNK ddPTM_HeLa_Curcumin_4h_R1 3 DSDLSHVQNK 10 0 O60506-4;O60506-3;O60506-2;O60506;F6UXX1 O60506-4 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 0 ;; ;; 125.57 0.00069776 12218700 18443.4 15620.1 14058.1 15238.1 19717.4 26249.3 17632 15245.2 20435.3 15778 FALSE FALSE TRUE 16983.58543 16970.23184 14579.10555 15175.04878 19482.28288 20804.89929 18126.70647 19893.3913 18193.59872 16326.28433 1.0402603 1.03944238 0.892983686 0.929485759 1.193307828 1.274319305 1.11027752 1.218488598 1.114374732 1 13.99490887 -5.745916732 24.80696593 1.005059316 1.198126986 0.664807423 0.068285941 93.84179193 149968.9307 0.008958079 0.017864735 1.80E-06 5.745916732 0.193067671 DSDQVAQS(ph)DGEESPAAEEQLLGEHIK ddPTM_HeLa_Curcumin_4h_R1 4 DSDQVAQSDGEESPAAEEQLLGEHIK 26 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H0Y8V7 D6REX3 SEC31A Protein transport protein Sec31A 1 0 DS(0.003)DQVAQS(0.99)DGEES(0.007)PAAEEQLLGEHIK;DS(0.001)DQVAQS(0.988)DGEES(0.011)PAAEEQLLGEHIK;DS(0.006)DQVAQS(0.968)DGEES(0.026)PAAEEQLLGEHIK;DS(0.002)DQVAQS(0.997)DGEES(0.001)PAAEEQLLGEHIK ;;; 121.66 1.04E-08 35378100 10336.4 11036.7 11412.7 9895 13801.8 12363.3 9473.8 7016.3 9068.2 8919.9 TRUE FALSE FALSE 9518.263033 11990.66317 11835.6647 9854.057112 13637.22255 9799.012217 9739.609331 9155.537571 8073.441148 9229.865861 1.031246085 1.299115648 1.282322504 1.067627337 1.477510373 1.061663557 1.055227614 0.99194698 0.874708394 1 13.17209397 -7.405055277 7.792617343 1.013723214 1.178738305 0.287580728 0.14499117 0.301233042 18.35007002 0.023486208 0.026783812 3.93E-08 7.405055277 0.165015091 DSDQVAQS(ph)DGEESPAAEEQLLGEHIKEEK ddPTM_HeLa_Curcumin_4h_R1 3 DSDQVAQSDGEESPAAEEQLLGEHIKEEK 29 1 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5;H0Y8V7 D6REX3 SEC31A Protein transport protein Sec31A 1 0 DS(0.005)DQVAQS(0.995)DGEESPAAEEQLLGEHIKEEK;DS(0.033)DQVAQS(0.965)DGEES(0.003)PAAEEQLLGEHIKEEK;DS(0.002)DQVAQS(0.997)DGEES(0.001)PAAEEQLLGEHIKEEK ;; 139.11 3.59E-12 41512800 7888.5 7142.2 7711.18 7457.3 9421 8073.9 6486.5 4443.71 5901.45 6080.2 TRUE FALSE FALSE 7264.116901 7759.539943 7996.963114 7426.443669 9308.660728 6399.282128 6668.493732 5798.576723 5254.0757 6291.486497 1.15459469 1.23333968 1.271076894 1.18039571 1.479564604 1.017133571 1.059923396 0.921654481 0.835108794 1 12.61918521 -2.907816347 13.66345997 1.117397601 1.141022668 0 0.178526724 0 0 0.021739055 0 0.00123647 2.907816347 0.023625067 DSDYVYPSLES(ph)DEDNPIFK ddPTM_HeLa_Curcumin_4h_R1 3 DSDYVYPSLESDEDNPIFK 19 0 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 0 DSDYVYPSLES(1)DEDNPIFK;DSDYVYPSLES(1)DEDNPIFK;DSDYVYPS(0.006)LES(0.994)DEDNPIFK ;; 151.21 2.37E-05 9951000 9013.4 7188.7 8253.6 9113.1 9351.2 11435.5 8206.1 6948.8 10591.8 8023.6 TRUE FALSE FALSE 8299.979879 7810.059196 8559.485677 9075.392407 9239.693047 9063.648395 8436.34108 9067.457132 9429.906039 8302.419503 0.999706155 0.940696768 1.030962802 1.093102126 1.112891615 1.091687597 1.016130428 1.092146347 1.135802164 1 13.01931611 -6.475100332 5.018407332 0.994962756 1.079037988 0.188798945 0.053404565 0.098142323 5.614456283 0.00463662 0.007032307 3.35E-07 6.475100332 0.084075232 DSEAFCHR ddPTM_HeLa_Curcumin_4h_R1 1 DSEAFCHR 8 0 C9JP16;O75718 C9JP16 CRTAP Cartilage-associated protein 0 0 100.02 0.012007 3988900 5092.4 4034.2 4437.2 3974.8 5047.1 4733.1 3258 2564.5 4784.6 4584.1 FALSE FALSE TRUE 4689.331167 4382.898272 4601.646535 3958.353331 4986.916629 3751.401707 3349.410712 3346.404244 4259.74135 4743.397134 0.988601847 0.923999857 0.970116228 0.834497559 1.051338627 0.790868148 0.706120659 0.705486838 0.898035992 1 12.21170495 -5.087508568 3.942880654 0.977943765 0.711705732 0.729979251 0.060635067 0.069375674 1.96867121 0.007853121 0.022061165 8.18E-06 5.087508568 -0.266238033 DSEEEAAS(ph)PEGK ddPTM_HeLa_Curcumin_4h_R1 2 DSEEEAASPEGK 12 0 A0A3B3ITU7;Q9HB96 A0A3B3ITU7 FANCE Fanconi anemia group E protein 1 0 DSEEEAAS(1)PEGK;DSEEEAAS(1)PEGK ; 156.81 0.00030518 15803200 4262.5 3744.4 3800.9 3873.2 4125.6 4617 3318 2258.1 4238.1 3904 TRUE FALSE FALSE 3925.118627 4068.049251 3941.764698 3857.173725 4076.404915 3659.382156 3411.09415 2946.584295 3773.191033 4039.663709 0.971644897 1.007026709 0.975765554 0.954825451 1.009095115 0.905863067 0.844400523 0.729413265 0.934035926 1 11.98001948 -4.467747157 1.159502771 0.986941206 0.661612555 0.906900429 0.025453956 0.168902132 0.236145301 0.002890751 0.060414773 3.41E-05 4.467747157 -0.325328652 DSEGDSLGARPGLPYGLS(ph)DDESGGGR ddPTM_HeLa_Curcumin_4h_R1 2 DSEGDSLGARPGLPYGLSDDESGGGR 26 1 Q8N8E2-2;Q8N8E2;C9JT52 Q8N8E2-2 ZNF513 Zinc finger protein 513 1 0 DSEGDSLGARPGLPY(0.012)GLS(0.965)DDES(0.023)GGGR;DSEGDS(0.001)LGARPGLPY(0.034)GLS(0.725)DDES(0.24)GGGR ; 60.517 0.0017116 21197000 2363.75 1583.58 2203.63 1855.65 2319.26 2818.21 2304.8 1601.83 2605.42 1955.47 TRUE FALSE FALSE 2176.656693 1720.457599 2285.298466 1847.971812 2291.604339 2233.681478 2369.466485 2090.220593 2319.611944 2023.422437 1.075730235 0.850271089 1.129422322 0.913290165 1.132538761 1.103912578 1.171019181 1.033012462 1.14638046 1 10.98258183 -5.692183151 24.99999943 1.021284833 1.114027656 0.194322923 0.090512541 54.38616546 19631.25635 0.011061404 0.022122806 2.03E-06 5.692183151 0.092742823 DSEGFNS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 DSEGFNSPK 9 0 I3L262;O43303-2;O43303 I3L262 CCP110 Centriolar coiled-coil protein of 110 kDa 1 0 DSEGFNS(1)PK;DSEGFNS(1)PK ; 103.43 0.011272 39274000 8900.8 7015.7 7992.7 8009.2 10342.3 10032 8650.2 6058.2 8607.7 7782.9 TRUE FALSE FALSE 8196.292288 7622.105847 8288.916493 7976.060053 10218.97483 7951.250116 8892.901331 7905.317291 7663.456845 8053.355196 1.017748763 0.946450971 1.029250082 0.990402119 1.268908992 0.987321424 1.104247995 0.98161786 0.951585601 1 12.97537425 DSEHIDDETRR ddPTM_HeLa_Curcumin_4h_R1 1 DSEHIDDETRR 11 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 0 0 73.666 0.010295 13967000 3748.2 2812.1 2991.4 3066.5 4367.3 5951.5 2927 1521.4 4458.6 3471 FALSE FALSE TRUE 3451.526015 3055.165394 3102.263916 3053.811636 4315.2228 4717.091813 3009.123742 1985.267856 3969.502735 3591.616992 0.960995012 0.850637861 0.863751319 0.850260939 1.201470761 1.313361593 0.837818662 0.552750436 1.105213263 1 11.81041779 -4.38488081 3.979806304 0.989682162 0.55729259 0.468351995 0.149340873 0.159306728 3.917787431 0.02066912 0.14690028 4.12E-05 4.38488081 -0.432389572 DSENLAS(ph)PSEYPENGER ddPTM_HeLa_Curcumin_4h_R1 1 DSENLASPSEYPENGER 17 0 A0A3B3ITD8;P52948-6;P52948-2;P52948-5;P52948;P52948-4;P52948-3 A0A3B3ITD8 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 0 DS(0.002)ENLAS(0.997)PS(0.001)EYPENGER 73.796 0.0072567 17414000 1627.1 1342.3 1301.8 1554.8 1521.4 2082.4 1745.9 2355 1697.7 1617.7 TRUE FALSE FALSE 1498.313318 1458.322431 1350.045853 1548.36665 1503.258299 1650.486767 1794.885255 3073.028659 1511.466557 1673.914955 0.895095246 0.871204613 0.806519978 0.924997202 0.898049387 0.986003956 1.072267889 1.835833207 0.902953016 1 10.70901052 -4.188345974 2.25727676 0.929281111 2.181138942 0.962282434 0.05461342 0.130017676 0.642478912 0.009447719 0.345468192 6.48E-05 4.188345974 1.251857831 S(ph)VVSDLEADDVK ddPTM_HeLa_Curcumin_4h_R1 3 SVVSDLEADDVK 12 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 S(0.977)VVS(0.023)DLEADDVK;S(0.99)VVS(0.01)DLEADDVK;S(1)VVSDLEADDVK ;; 214.61 3.67E-13 23530000 4424.83 2356.98 3795.09 4085.74 4592.05 6372.79 10239.81 12750.78 3453.82 2695.44 TRUE FALSE FALSE 4074.600036 2560.706849 3935.739374 4068.83429 4537.292803 5051.001518 10527.11151 16638.43412 3074.944587 2789.106339 1.460898059 0.918110153 1.411111265 1.458830821 1.626790897 1.81097488 3.774367209 5.965507263 1.102483811 1 11.44558723 -4.316806097 1.191506794 1.229878667 7.982730734 0.982042433 0.202906962 0.134957549 0.167820534 0.033958841 1.096133226 4.82E-05 4.316806097 6.752852067 up DSET(ph)VDEDEEVDPALTVGTIKK ddPTM_HeLa_Curcumin_4h_R1 1 DSETVDEDEEVDPALTVGTIKK 22 1 A0A3B3IUD7;Q14690 A0A3B3IUD7 PDCD11 Protein RRP5 homolog 1 0 DS(0.213)ET(0.787)VDEDEEVDPALTVGTIKK 89.891 0.00018501 4534300 1533.8 1402.9 1371.5 2071 1634.3 1892.8 1277.5 986.63 1981.6 1424.7 TRUE FALSE FALSE 1412.398112 1524.160425 1422.328996 2062.430751 1614.81204 1500.211944 1313.343212 1287.448945 1764.223438 1474.208219 0.958072336 1.033884091 0.964808755 1.399009125 1.095375822 1.017639113 0.890880403 0.873315539 1.19672609 1 10.52572459 -4.750963579 5.325604036 1.022908256 0.878984201 0.161860059 0.136084198 0.241155586 20.10200221 0.018620489 0.067069495 1.77E-05 4.750963579 -0.143924056 DSETGENIR ddPTM_HeLa_Curcumin_4h_R1 2 DSETGENIR 9 0 P38646 P38646 HSPA9 "Stress-70 protein, mitochondrial" 0 0 ; ; 107.57 0.0044132 1511790 858.65 687.52 834 1090.75 1090.34 1427.46 1063.64 861.33 1230.89 685.36 FALSE FALSE TRUE 790.6869465 746.9461653 864.9087737 1086.236766 1077.338408 1131.388705 1093.482876 1123.945552 1095.864447 709.176209 1.114937214 1.053258916 1.219596431 1.531688108 1.519140651 1.595356261 1.541905752 1.584860769 1.545263973 1 9.470000328 -6.38613147 2.141057177 1.054392304 1.563959732 0.524002972 0.15890843 0.039789018 0.357356012 0.007531235 0.012386218 4.11E-07 6.38613147 0.509567428 DSFDDRGPSLNPVLDYDHGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 DSFDDRGPSLNPVLDYDHGSR 21 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 0 DSFDDRGPSLNPVLDY(0.002)DHGS(0.998)R 80.68 0.00043129 11131000 3631.8 3800.4 4074.6 3667.6 3860.3 4820.2 5548.6 4821.8 4211.5 3880.8 TRUE FALSE FALSE 3344.339198 4128.889642 4225.60826 3652.424443 3814.268444 3820.436185 5704.278783 6291.944623 3749.508987 4015.657511 0.832824809 1.028197656 1.052283032 0.909545805 0.949849043 0.951384966 1.420509286 1.566852902 0.933722305 1 11.97142051 -4.70401593 3.585238652 0.937826475 1.538037496 0.922282712 0.062675843 0.050020557 1.266587785 0.011184806 0.047604567 1.98E-05 4.70401593 0.600211021 DSFDDRGPSLNPVLDYDHGSR ddPTM_HeLa_Curcumin_4h_R1 2 DSFDDRGPSLNPVLDYDHGSR 21 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 0 ; ; 144.17 6.13E-06 18439900 8819.2 6926.8 6876 7346.6 9846.4 18638.4 7853.8 4255.8 11330.5 7878.3 FALSE FALSE TRUE 8121.151014 7525.521727 7130.830609 7316.201716 9728.988111 14772.58574 8074.156491 5553.373829 10087.5725 8152.070339 0.996207181 0.923142394 0.874726335 0.89746548 1.193437704 1.812126874 0.990442447 0.681222511 1.237424615 1 12.99295078 -5.745978538 22.62609647 0.97532504 1.20244732 0.086276358 0.278757613 121.8819716 178363.3537 0.038514095 0.076722038 1.79E-06 5.745978538 0.22712228 KASATCSSATAAASS(ph)GLEEWTSRSPR ddPTM_HeLa_Curcumin_4h_R1 1 KASATCSSATAAASSGLEEWTSRSPR 26 2 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74;H7BZQ3;Q96G74-4 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 0 KASATCSSAT(0.003)AAAS(0.206)S(0.613)GLEEWT(0.044)S(0.044)RS(0.088)PR 43.932 0.011915 33592000 1747.4 1533.2 1564.6 1651.2 1506 1630.1 993.23 629.96 1870.9 1681.1 TRUE FALSE FALSE 1609.091446 1665.722976 1622.585452 1644.367772 1488.041934 1291.998885 1021.097361 822.031904 1665.666951 1739.5181 0.925021387 0.95757726 0.932778712 0.945300754 0.855433429 0.742733798 0.587000136 0.472563007 0.957545053 1 10.76447198 -4.759227258 0.880253614 0.964044595 0.366099544 0.987175682 0.019245769 0.128002528 0.114707711 0.004579655 0.062156835 1.74E-05 4.759227258 -0.597945052 down DSFQAS(ph)GYSGMDVT(ph)LLDPT(ph)CK ddPTM_HeLa_Curcumin_4h_R1 1 DSFQASGYSGMDVTLLDPTCK 21 0 Q03167-2;Q03167 Q03167-2 TGFBR3 Transforming growth factor beta receptor type 3 3 0 DS(0.035)FQAS(0.924)GY(0.041)S(0.138)GMDVT(0.938)LLDPT(0.923)CK 51.487 0.0073369 0 1565.7 1361.9 1181.1 1322.8 1333.8 1818.8 1323.6 1000 1827.8 1321.9 TRUE FALSE FALSE 1441.773193 1479.616567 1224.872605 1317.326604 1317.895306 1441.560378 1360.736654 1304.895397 1627.294913 1367.835927 1.054054192 1.081720796 0.895482112 0.963073552 0.96348932 1.053898607 0.994809851 0.953985322 1.189685752 1 10.41767947 -6.780940483 24.99104947 1.030453436 0.974976673 0.304402688 0.065668405 250.9942067 321653.0142 0.007415376 0.009753732 1.66E-07 6.780940483 -0.055476763 DSGLES(ph)PAAAEAPLR ddPTM_HeLa_Curcumin_4h_R1 1 DSGLESPAAAEAPLR 15 0 H0YM15;J3KNL7;Q8NBR6-2;Q8NBR6 H0YM15 FAM63B Protein FAM63B 1 0 DSGLES(1)PAAAEAPLR 182.7 4.14E-05 4791200 1133.4 1231.7 1217.5 981.67 1225.2 1550.6 1448.5 1614.4 1238.9 1310.9 TRUE FALSE FALSE 1043.690194 1338.16266 1262.621621 977.6081096 1210.59029 1228.988081 1489.141012 2106.623128 1102.99577 1356.453677 0.769425607 0.98651556 0.930825462 0.720708806 0.892467108 0.906030262 1.097819289 1.553037279 0.813146654 1 10.40562407 -4.263568933 1.868400766 0.886009716 1.765952847 0.855300222 0.08471527 0.266408784 0.942942013 0.01447536 0.407141178 5.45E-05 4.263568933 0.879943131 DSGNWDTSGSELS(ph)EGELEK ddPTM_HeLa_Curcumin_4h_R1 2 DSGNWDTSGSELSEGELEK 19 0 O75400-2;O75400-3;O75400 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 0 DSGNWDTSGS(0.047)ELS(0.953)EGELEK;DSGNWDTSGS(0.037)ELS(0.962)EGELEK ; 152.86 3.92E-05 12524100 4452 3802.1 3857.3 4427.8 4848.8 5832 2969.8 2361.6 4685.6 4279.3 TRUE FALSE FALSE 4099.619502 4130.736582 4000.254931 4409.478937 4790.981227 4622.37746 3053.124595 3081.640969 4171.601403 4428.005356 0.925838876 0.932866212 0.903398846 0.99581608 1.081972771 1.043896086 0.689503365 0.69594337 0.942094931 1 12.11244125 -4.752778275 24.99891803 0.972375066 0.692723196 0.82367737 0.052783965 61.36971772 177129.8816 0.008247226 0.029907967 1.77E-05 4.752778275 -0.27965187 DSGNWDTSGSELS(ph)EGELEKR ddPTM_HeLa_Curcumin_4h_R1 1 DSGNWDTSGSELSEGELEKR 20 1 O75400-2;O75400-3;O75400 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 0 DSGNWDT(0.003)S(0.002)GS(0.073)ELS(0.922)EGELEKR 101.71 0.00021519 48868000 649.35 473.24 598.12 695.98 573.84 875.15 613.42 452.99 794.06 634.69 TRUE FALSE FALSE 597.9532623 514.1447569 620.2868534 693.1002192 566.9973328 693.634025 630.6309143 591.1045657 706.9536046 656.7454303 0.910479517 0.782867658 0.944485983 1.055355983 0.863344161 1.056168788 0.960236471 0.900051281 1.076449979 1 9.359190447 -6.494468952 24.91372816 0.939633039 0.969253065 0.017544331 0.088793747 2486.956263 2180916.705 0.012701638 0.019374617 3.20E-07 6.494468952 0.029620026 GSGSQS(ph)SVPSVDQFTGVGIR ddPTM_HeLa_Curcumin_4h_R1 1 GSGSQSSVPSVDQFTGVGIR 20 0 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1 0 GS(0.001)GS(0.176)QS(0.647)S(0.175)VPS(0.001)VDQFTGVGIR 117.29 0.00013276 19506000 1221.4 1234.8 1132.3 1412.1 1312 1637.4 1895.9 1882.7 1227.4 1130 TRUE FALSE FALSE 1124.724901 1341.53061 1174.264034 1406.257104 1296.355257 1297.784783 1949.093851 2456.726563 1092.757291 1169.267416 0.961905622 1.147325746 1.00427329 1.202682197 1.108690142 1.109912724 1.666935916 2.101081865 0.93456576 1 10.1913892 -4.315861456 1.115687085 1.0100202 2.614655074 0.93597802 0.089423405 0.244708462 0.258905536 0.01337769 0.448794427 4.83E-05 4.315861456 1.604634874 up DSGPPTK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 DSGPPTKK 8 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 0 1 ; DSGPPTK(1)K;DSGPPTK(1)K 120.87 0.00088687 92048000 8520.9 8519.1 8933.9 7410.2 9065 10337 10105.2 9309.6 7603.4 6337.8 FALSE TRUE FALSE 7846.461774 9255.453044 9264.998193 7379.538556 8956.905796 8192.989678 10388.72472 12148.05418 6769.326043 6558.038078 1.196464809 1.411314319 1.412769807 1.125266195 1.365790453 1.249304987 1.584120829 1.852391529 1.032218167 1 12.67904856 -1 0.204695975 1.018246389 4.478688048 0.704894628 0.134778637 21.69248156 0.251580209 0.128050975 24.44527486 0.1 1 3.460441659 DSGREDEPGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 DSGREDEPGSPR 12 1 Q2TAM9 Q2TAM9 TUSC1 Tumor suppressor candidate gene 1 protein 1 0 DSGREDEPGS(1)PR;DSGREDEPGS(1)PR;DSGREDEPGS(1)PR ;; 82.483 0.009751 126266800 12610.7 10263.9 11871.7 11364.8 11560.1 14044 11324.9 11321.1 13147.6 11821.9 TRUE FALSE FALSE 11612.54979 11151.06578 12311.67565 11317.77547 11422.25336 11131.11609 11642.64621 14772.85127 11705.34117 12232.71015 0.94930311 0.9115777 1.006455274 0.925205889 0.933746751 0.909946852 0.951763434 1.207651542 0.956888624 1 13.57845645 -4.260060358 24.94777543 0.961507934 1.207651625 0.842086734 0.033177176 38.79135442 701694.1937 0.005252106 0.0440019 5.49E-05 4.260060358 0.246143691 AMADELS(ph)EK ddPTM_HeLa_Curcumin_4h_R1 3 AMADELSEK 9 0 Q03135;E9PCT5 Q03135 CAV1 Caveolin-1;Caveolin 1 0 AMADELS(1)EK;AMADELS(1)EK;AMADELS(1)EK ;; 139.43 0.0024365 135265000 9335.3 7379.8 9137.3 12618.2 9666.2 9341.4 4525 1885.43 12507.2 9839.7 TRUE FALSE FALSE 8596.401154 8017.677028 9475.936376 12565.98923 9550.936878 7403.888341 4651.959322 2460.288928 11135.19145 10181.62884 0.8443051 0.787465066 0.93068963 1.234182607 0.938055887 0.727181127 0.456897358 0.241640013 1.093655212 1 13.31368076 -4.758953985 1.879614009 0.938246784 0.250603787 0.804992575 0.123437055 0.132449382 0.837323045 0.018247115 0.11318879 1.74E-05 4.758953985 -0.687642997 down DSGRLS(ph)PDLSVCGQPR ddPTM_HeLa_Curcumin_4h_R1 1 DSGRLSPDLSVCGQPR 16 1 Q8TF76-2;Q8TF76 Q8TF76-2 GSG2 Serine/threonine-protein kinase haspin 1 0 DS(0.057)GRLS(0.943)PDLSVCGQPR 74.744 0.0071979 0 866.54 728.44 658.77 909.06 746.36 1094.1 526.69 409.8 992.52 936.13 TRUE FALSE FALSE 797.9524446 791.4031077 683.1845957 905.2985506 737.4601445 867.171327 541.4675039 534.7461335 883.6430392 968.6604478 0.823768996 0.817007765 0.705288006 0.934588124 0.761319558 0.895227351 0.558985871 0.552047041 0.912231981 1 9.919847225 -2.65715844 0.136977527 1.04764341 1.72E-22 0.543688729 0.0980095 27.09981985 0.382251278 0.338705765 5.242710053 0.002202123 2.65715844 -1.04764341 DSGS(ph)DQDLDGAGVR ddPTM_HeLa_Curcumin_4h_R1 2 DSGSDQDLDGAGVR 14 0 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 0 DS(0.011)GS(0.989)DQDLDGAGVR;DS(0.095)GS(0.905)DQDLDGAGVR ; 128.82 0.0011307 16791400 2623.1 2456.43 2375.42 2588.8 2439.3 2857.8 1966.7 2092.58 2858.3 2595.6 TRUE FALSE FALSE 2415.478867 2668.752864 2463.455155 2578.088232 2410.212941 2265.060066 2021.880309 2730.598009 2544.751641 2685.796907 0.899352762 0.993654009 0.917215724 0.95989694 0.897392105 0.843347485 0.752804616 1.016680748 0.947484761 1 11.3911345 -5.584894672 3.477358115 0.952317649 0.859889641 0.235282411 0.066722922 0.236834045 5.812145821 0.009803855 0.021115723 2.60E-06 5.584894672 -0.092428008 DSGS(ph)ISLQETR ddPTM_HeLa_Curcumin_4h_R1 3 DSGSISLQETR 11 0 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 0 DS(0.083)GS(0.858)IS(0.058)LQETR;DS(0.034)GS(0.916)IS(0.047)LQET(0.003)R;DS(0.007)GS(0.953)IS(0.04)LQETR ;; 151.66 0.00051067 161471000 5023.62 3971.87 5338.56 6053.73 5813.85 5907.39 3894.25 1649.01 4472.63 3477.78 TRUE FALSE FALSE 4625.995176 4315.180744 5536.41173 6028.681269 5744.523636 4682.130724 4003.512174 2151.785558 3981.993679 3598.632596 1.285486932 1.199116784 1.538476514 1.675270011 1.596307342 1.301086065 1.112509284 0.597945331 1.106529653 1 11.8132331 -2.807835072 13.70294157 1.212869801 1.214000094 0 0.304126397 0 0 0.043103399 0 0.001556557 2.807835072 0.001130293 DSGS(ph)QEVLSELR ddPTM_HeLa_Curcumin_4h_R1 2 DSGSQEVLSELR 12 0 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2;X6RJY0 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 0 DS(0.071)GS(0.929)QEVLSELR;DS(0.026)GS(0.974)QEVLSELR ; 167.92 0.00012587 41582000 2522.87 1888.71 2552.44 2336.24 2649.85 3074.9 3719.8 3123 2338.56 2120.89 TRUE FALSE FALSE 2323.182177 2051.961676 2647.035672 2326.573258 2618.252269 2437.131079 3824.167577 4075.188323 2082.025819 2194.59077 1.058594709 0.935008797 1.206163677 1.060139909 1.193048064 1.110517329 1.74254245 1.856924024 0.948708 1 11.09973623 -4.747687905 3.445000997 1.049168511 1.843117667 0.923698977 0.084944569 0.038754902 0.944132205 0.011527721 0.047128226 1.79E-05 4.747687905 0.793949155 DSGSDLSHRPK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 DSGSDLSHRPKR 12 2 O95251-4;O95251;E7EUP3;D6RFZ5 O95251-4 KAT7 Histone acetyltransferase KAT7;Histone acetyltransferase 0 1 ; DSGSDLSHRPK(1)R;DSGSDLSHRPK(1)R 96.113 0.002345 2114800 1161.2 1088.89 916.05 946.56 1792.91 2633.88 842.51 829.82 1885.55 966.46 FALSE TRUE FALSE 1069.289795 1183.0088 949.9996188 942.6433855 1771.530719 2087.583598 866.1485631 1082.828298 1678.709882 1000.044413 1.069242306 1.182956261 0.949957428 0.942601522 1.771452044 2.087490886 0.866110096 1.082780208 1.678635329 1 9.965848358 -5.782109914 24.99275814 1.033454568 1.455507286 0.107167066 0.379707023 235.0369937 284182.9314 0.048345469 0.087702951 1.65E-06 5.782109914 0.422052718 DSGSDQDLDGAGVRAS(ph)DLEDEESAAR ddPTM_HeLa_Curcumin_4h_R1 2 DSGSDQDLDGAGVRASDLEDEESAAR 26 1 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 0 DSGSDQDLDGAGVRAS(1)DLEDEESAAR;DSGSDQDLDGAGVRAS(0.982)DLEDEES(0.018)AAR ; 98.991 1.87E-06 55306000 3594.6 2897.3 3699.8 3559.4 3681.1 4223.9 3001.3 2635.81 3146.6 3083.6 TRUE FALSE FALSE 3310.083617 3147.729702 3836.917843 3544.672146 3637.205287 3347.815527 3085.5084 3439.456335 2801.425852 3190.75487 1.037398281 0.986515677 1.202511004 1.110919607 1.139919998 1.049223667 0.967015182 1.077944397 0.87798216 1 11.63968206 DSGSDTASAIIPST(ph)TPS(ph)VDS(ph)DDES(ph)VVKDKK ddPTM_HeLa_Curcumin_4h_R1 1 DSGSDTASAIIPSTTPSVDSDDESVVKDKK 30 2 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 4 0 DSGSDTASAIIPS(0.511)T(0.681)T(0.589)PS(0.659)VDS(0.785)DDES(0.773)VVKDKK 58.998 0.00074939 4127300 561.67 589.82 409.95 444.63 516.56 682.76 576.33 288.07 531.62 378.11 TRUE FALSE FALSE 517.2132268 640.8014126 425.1431076 442.7902389 510.4003594 541.1478797 592.5002687 375.9012169 473.302616 391.2492944 1.321953124 1.63783404 1.086629711 1.131734281 1.304540013 1.383128066 1.514380415 0.960771616 1.209721328 1 8.61194434 -9.125288015 0.946457746 1.00444893 1.300424344 0.089635837 0.198858256 0.583517566 0.964263441 0.112706083 0.034962562 7.49E-10 9.125288015 0.295975415 DSGSDTASAIIPSTTPSVDS(ph)DDESVVK ddPTM_HeLa_Curcumin_4h_R1 2 DSGSDTASAIIPSTTPSVDSDDESVVK 27 0 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 1 0 DSGSDTASAIIPSTTPS(0.011)VDS(0.957)DDES(0.033)VVK;DSGSDTASAIIPS(0.005)T(0.005)T(0.005)PS(0.159)VDS(0.713)DDES(0.111)VVK ; 157.01 8.13E-10 13104000 6725.4 5157.6 6849.7 6626.1 8479.3 7781.5 5380.6 4125 5983.4 4700.4 TRUE FALSE FALSE 6193.077493 5603.399962 7103.555908 6598.682954 8378.189886 6167.529184 5531.565155 5382.693511 5327.03599 4863.73855 1.273316283 1.152076721 1.460513519 1.356710046 1.722582289 1.26806347 1.137307258 1.106698778 1.095255416 1 12.24784996 -8.737704912 0.604786331 0.991344008 1.329711673 0.269855693 0.172735055 0.812784905 0.560630919 0.138042327 0.044831575 1.83E-09 8.737704912 0.338367665 DSGSDTASAIIPSTTPSVDS(ph)DDESVVKDKK ddPTM_HeLa_Curcumin_4h_R1 1 DSGSDTASAIIPSTTPSVDSDDESVVKDKK 30 2 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 1 0 DSGSDTASAIIPS(0.011)T(0.011)T(0.011)PS(0.182)VDS(0.784)DDESVVKDKK 94.295 2.31E-08 38000000 4487 2746 3052.6 3582.7 3579.1 4306.3 3001.5 2042.3 4172.4 3400.1 TRUE FALSE FALSE 4131.849215 2983.352004 3165.732041 3567.875737 3536.42157 3413.124838 3085.714012 2664.987868 3714.698159 3518.253222 1.17440359 0.84796398 0.899802215 1.014104305 1.005164025 0.970119154 0.877058534 0.757474718 1.055835929 1 11.78064361 -2.789024755 0.370648299 1.065856223 5.89E-15 0.398686851 0.087006781 11.74341605 0.48190411 0.029975097 7.069430038 0.001625456 2.789024755 -1.065856223 DSGSS(ph)SPLPK ddPTM_HeLa_Curcumin_4h_R1 3 DSGSSSPLPK 10 0 Q86VQ1;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 0 DS(0.001)GS(0.061)S(0.561)S(0.376)PLPK;DSGS(0.001)S(0.926)S(0.072)PLPK;DSGSS(0.5)S(0.5)PLPK ;; 181.53 0.00027765 55807000 21655.9 19901.3 21118.2 21180.6 24365.9 23006.1 16952.6 10273 18332.9 17588.3 TRUE FALSE FALSE 19941.81266 21621.47969 21900.85907 21092.96029 24075.35256 18234.37553 17428.24433 13405.19041 16321.82674 18199.49212 1.09573457 1.188026542 1.203377486 1.158986204 1.322858484 1.001916724 0.957622565 0.736569478 0.896828694 1 14.15161057 -4.405549395 1.887999677 1.094037902 0.688252644 0.506767596 0.114469196 0.396809756 1.816991925 0.016319563 0.253579948 3.93E-05 4.405549395 -0.405785258 DSGSSS(ph)PLPK ddPTM_HeLa_Curcumin_4h_R1 1 DSGSSSPLPK 10 0 Q86VQ1;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 0 DSGS(0.001)S(0.154)S(0.845)PLPK 118.23 0.0048725 18149000 4213.5 3307.9 3952.1 3623.7 3890 3925.9 3037.3 1935.9 3507.2 3115.6 TRUE FALSE FALSE 3879.997029 3593.820136 4098.568303 3608.70609 3843.614291 3111.624086 3122.518464 2526.146998 3122.468935 3223.866868 1.203522722 1.114754512 1.271320582 1.119371934 1.192237288 0.965183804 0.968563092 0.783576711 0.968547729 1 11.65457645 -4.574874303 1.362477243 1.119301124 0.756770844 0.566793739 0.091903902 0.462303046 1.10882197 0.014638018 0.195952683 2.66E-05 4.574874303 -0.36253028 DSGSSSVSSTSSSSSSS(ph)PGDK ddPTM_HeLa_Curcumin_4h_R1 2 DSGSSSVSSTSSSSSSSPGDK 21 0 Q9H7S9 Q9H7S9 ZNF703 Zinc finger protein 703 1 0 DSGSSSVSSTSSSS(0.001)S(0.005)S(0.043)S(0.951)PGDK;DSGSSSVSST(0.001)SS(0.001)S(0.01)S(0.01)S(0.087)S(0.087)S(0.804)PGDK ; 238.88 1.52E-37 8343000 3540.2 4613.7 3783.1 4699.9 3473.5 4253.8 3168.3 2177.4 5044 4801 TRUE FALSE FALSE 3259.989434 5012.48767 3923.305014 4680.453059 3432.080781 3371.51393 3257.193971 2841.279236 4490.685819 4967.834393 0.656219426 1.008988479 0.789741506 0.942151587 0.690860546 0.678668744 0.655656713 0.571935176 0.903952399 1 12.27840137 -13.52287875 0.231763618 2.412967324 0.702181293 0.323801996 0.125765944 41.81149147 0.540037761 27.15742083 0.096316836 3.00E-14 13.52287875 -1.710786031 DSGYIDCWDSERSDSLS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 2 DSGYIDCWDSERSDSLSPPR 20 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 DSGYIDCWDSERS(0.003)DS(0.042)LS(0.954)PPR;DSGYIDCWDS(0.006)ERS(0.107)DS(0.049)LS(0.838)PPR ; 81.643 0.0010825 116433000 5051.6 3820.8 4123.2 4841.6 3585.7 5994.5 3447.6 3373.3 5645.8 4509.2 TRUE FALSE FALSE 4651.76053 4151.052927 4276.009419 4821.566742 3542.942869 4751.173128 3544.330377 4401.803641 5026.469865 4665.894364 0.99697082 0.889658574 0.916439397 1.033363888 0.759327707 1.018277046 0.759625079 0.943399764 1.077278968 1 12.18793793 -6.632761869 0.549738291 1.004615708 0.871825834 0.260092466 0.089727247 0.829370926 0.521460345 0.022167136 0.044456758 2.33E-07 6.632761869 -0.132789873 YMLTHQELAS(ph)DGEIETK ddPTM_HeLa_Curcumin_4h_R1 7 YMLTHQELASDGEIETK 17 0 Q02241-2;A0A2U3TZL8;H7BYN4;Q02241-3;Q02241 Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 0 YMLTHQELAS(0.999)DGEIETK;YMLTHQELAS(1)DGEIETK;YMLT(0.005)HQELAS(0.994)DGEIET(0.001)K;YMLTHQELAS(1)DGEIETK;YMLTHQELAS(1)DGEIETK;YMLTHQELAS(1)DGEIETK;YMLTHQELAS(0.999)DGEIET(0.001)K ;;;;;; 150.91 0.00024697 343192500 29266.7 20299.3 26460.2 31088.2 26071.5 26824.1 11366.53 4872.7 33610.9 25720.6 TRUE FALSE FALSE 26950.20981 22053.88104 27440.83829 30959.56527 25760.61439 21260.47929 11685.44424 6358.363799 29923.86836 26614.38894 1.012618019 0.828645027 1.031052727 1.163264178 0.967920566 0.79883402 0.439064908 0.238906999 1.124349255 1 14.69991882 -4.756665844 1.803739571 1.004966404 0.22636409 0.910225696 0.085448583 0.076733838 0.438850206 0.011272026 0.073166953 1.75E-05 4.756665844 -0.778602315 down DSIS(ph)SDSETSEPLSCR ddPTM_HeLa_Curcumin_4h_R1 3 DSISSDSETSEPLSCR 16 0 O75164 O75164 KDM4A Lysine-specific demethylase 4A 1 0 DSIS(0.488)S(0.488)DS(0.015)ET(0.007)S(0.002)EPLSCR;DSIS(0.877)S(0.123)DSETSEPLSCR;DSIS(0.959)S(0.041)DSETSEPLSCR ;; 220.25 1.92E-15 56459000 8195.27 6248.56 7353.15 7479.12 6936.94 8304.67 4811.21 3245.61 7763.33 7233.7 TRUE FALSE FALSE 7546.605732 6788.657683 7625.664207 7448.173383 6854.221521 6582.187829 4946.199604 4235.181548 6911.712122 7485.070537 1.008221058 0.906959747 1.018783213 0.995070567 0.915719029 0.879375525 0.660808683 0.565817186 0.923399731 1 12.8698002 -4.686189412 1.136910286 0.996917155 0.485752422 0.918271563 0.04176567 0.124044907 0.204843505 0.005083486 0.062830518 2.06E-05 4.686189412 -0.511164733 DSISAVSS(ph)EKVSPSK ddPTM_HeLa_Curcumin_4h_R1 1 DSISAVSSEKVSPSK 15 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 DSIS(0.02)AVS(0.26)S(0.645)EKVS(0.075)PSK 125.36 0.0087905 5946000 3107 2720.9 2639.6 2635.5 3931.6 3150.6 2747.3 2804 2687.6 2298.1 TRUE FALSE FALSE 2861.077672 2956.082472 2737.425898 2624.594999 3884.718238 2497.130045 2824.381844 3658.926692 2392.777004 2377.958804 1.203165365 1.243117613 1.151166241 1.103717606 1.633635634 1.050114931 1.187733715 1.538683801 1.006231479 1 11.21550801 -13.52287875 0.075277834 0.048805564 1.579113369 0.329873259 0.166774293 179.5017028 1.043224333 29.07852614 3.643806364 3.00E-14 13.52287875 1.530307804 DSISAVSSEKVS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 DSISAVSSEKVSPSK 15 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 DSISAVSSEKVS(0.956)PS(0.044)K 109.14 0.0026814 0 1025.2 1042.6 1130.5 1162.2 1254 1158.7 1026.1 891.94 599.89 771.55 TRUE FALSE FALSE 944.0543382 1132.717698 1172.397324 1157.391124 1239.046869 918.3725588 1054.889604 1163.8884 534.0835679 798.3613051 1.182490098 1.418803355 1.468504695 1.449708443 1.551987629 1.150321982 1.321318553 1.457846708 0.668974767 1 9.640897988 -7.635091461 1.311015307 1.053501795 1.401281687 0.603870111 0.162584654 0.178103397 0.627304163 0.025201007 0.025355742 2.32E-08 7.635091461 0.347779892 DSISAVSSEKVS(ph)PSKSPSLSPSPPS(ph)PLEK ddPTM_HeLa_Curcumin_4h_R1 2 DSISAVSSEKVSPSKSPSLSPSPPSPLEK 29 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 DS(0.064)IS(0.211)AVS(0.19)S(0.203)EKVS(0.288)PS(0.033)KS(0.006)PS(0.01)LS(0.028)PS(0.187)PPS(0.779)PLEK;DSISAVS(0.001)S(0.001)EKVS(0.668)PS(0.233)KS(0.036)PS(0.039)LS(0.042)PS(0.18)PPS(0.799)PLEK ; 81.986 3.10E-06 193775000 5935.4 4809.6 5438.8 6218 6382.9 6742.7 5447.1 6589.7 5346.8 4321 TRUE FALSE FALSE 5465.606827 5225.320393 5640.366712 6192.271564 6306.788086 5344.188014 5599.930966 8598.869195 4760.269417 4471.154428 1.222415131 1.168673656 1.261501208 1.384937976 1.41055027 1.195259099 1.252457515 1.923187699 1.064662269 1 12.12643166 -1 0.180685758 1.007510764 3.586132324 0.588751371 0.15574263 31.30755431 0.340639884 0.196117636 22.32557779 0.1 1 2.57862156 NSTDLDSAPEDPT(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 NSTDLDSAPEDPTSPK 16 0 I3L2J0;A0A0A0MQR4;Q96RK0;I3L373;I3L135;I3L1Q4 I3L2J0 CIC Protein capicua homolog 1 0 NSTDLDSAPEDPT(0.782)S(0.218)PK 201.16 9.58E-10 22742000 6251 6019.6 6371 7011.6 5916.7 5475.9 2033.8 631.63 6272.1 4343.7 TRUE FALSE FALSE 5756.226754 6539.907401 6607.114865 6982.587857 5846.147217 4340.136614 2090.862954 824.2110793 5584.066322 4494.643252 1.280686015 1.455044824 1.469997616 1.553535501 1.300692155 0.965624271 0.465189969 0.183376307 1.242382545 1 12.1339909 -4.756146396 2.206743276 1.227555162 0.20666777 0.844428108 0.168839679 0.128639804 1.178084057 0.032173195 0.172981723 1.75E-05 4.756146396 -1.020887392 down DSISAVSSEKVSPS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 DSISAVSSEKVSPSK 15 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 DSISAVSSEKVS(0.219)PS(0.781)K 157.91 0.0032722 8421500 1222.1 1238.6 1409.4 1172 2079 1898.5 1317.3 1070.8 1075.9 1003.8 TRUE FALSE FALSE 1125.369495 1345.659065 1461.633604 1167.150575 2054.209283 1504.729699 1354.259893 1397.281991 957.8764618 1038.681975 1.083459155 1.295544832 1.407200316 1.123684248 1.977707645 1.448691453 1.303825353 1.345245247 0.922203797 1 10.02053828 -7.040257578 1.064445698 1.023779655 1.464702943 0.471327977 0.20627346 0.301910445 0.670012839 0.040742229 0.054035889 9.11E-08 7.040257578 0.440923288 DSK(ac)PSSTPR ddPTM_HeLa_Curcumin_4h_R1 2 DSKPSSTPR 9 1 P06748;P06748-3 P06748 NPM1 Nucleophosmin 0 1 ; DSK(1)PSSTPR;DSK(1)PSSTPR 98.04 0.01165 1236230 0 0 72.816 0 0 124.74 0 154.35 0 0 FALSE TRUE FALSE 0 0 75.51462502 0 0 98.86751789 0 201.4106045 0 0 0 DSLGDFIEHYAQLGPS(ph)SPEQLAAGAEEGGGPR ddPTM_HeLa_Curcumin_4h_R1 3 DSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPR 32 0 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 0 DSLGDFIEHYAQLGPS(0.878)S(0.122)PEQLAAGAEEGGGPR;DSLGDFIEHY(0.004)AQLGPS(0.498)S(0.498)PEQLAAGAEEGGGPR;DSLGDFIEHY(0.001)AQLGPS(0.565)S(0.434)PEQLAAGAEEGGGPR ;; 153.83 3.37E-14 131433000 3683.44 2798.62 2899.66 2759.08 3366.39 4555.85 3704.56 2917 3577.18 3386.39 TRUE FALSE FALSE 3391.891837 3040.520242 3007.12395 2747.663658 3326.247998 3610.915355 3808.499983 3806.379872 3184.772304 3504.0668 0.967987208 0.867711838 0.858181114 0.784135639 0.949253592 1.030492728 1.08687996 1.086274917 0.908878878 1 11.77481456 -5.064459686 3.067861804 0.948475029 1.084584274 0.48931776 0.068116389 0.23510525 4.31824193 0.011866285 0.036657323 8.62E-06 5.064459686 0.136109245 DSLGDFIEHYAQLGPS(ph)SPEQLAAGAEEGGGPRR ddPTM_HeLa_Curcumin_4h_R1 3 DSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPRR 33 1 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 0 DSLGDFIEHYAQLGPS(0.5)S(0.5)PEQLAAGAEEGGGPRR;DSLGDFIEHY(0.001)AQLGPS(0.499)S(0.499)PEQLAAGAEEGGGPRR;DSLGDFIEHY(0.006)AQLGPS(0.497)S(0.497)PEQLAAGAEEGGGPRR ;; 74.733 9.65E-06 62224000 6107.82 5461.65 4852.51 5022.17 5199.55 7533.6 5017.95 5299.76 6738.5 5525.35 TRUE FALSE FALSE 5624.379602 5933.730689 5032.348289 5001.389591 5137.548762 5971.046439 5158.740172 6915.632427 5999.303409 5717.355501 0.983737954 1.037845327 0.880188102 0.874773239 0.8985883 1.044372077 0.902294806 1.20958587 1.049314392 1 12.48113228 -4.25074187 24.84434549 0.972620596 1.209586016 0.546023238 0.066859615 841.6612408 1954669.368 0.008843027 0.170603369 5.61E-05 4.25074187 0.23696542 SWSTAT(ph)SPLGGERPFR ddPTM_HeLa_Curcumin_4h_R1 1 SWSTATSPLGGERPFR 16 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0;H0Y8P3;Q9UPQ0-2;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46;D6RJ93;Q6NVB9 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 SWSTAT(0.5)S(0.5)PLGGERPFR 195.6 1.97E-06 202710000 3420.9 2528.7 2925.8 2647.5 2739.3 3850 4414.4 5672.4 3095.2 2633.9 TRUE FALSE FALSE 3150.132155 2747.26956 3034.232722 2636.545346 2706.635637 3051.466602 4538.256183 7401.888647 2755.664304 2725.427829 1.155830333 1.008014056 1.113305107 0.967387695 0.993104865 1.119628474 1.665153682 2.715863017 1.011094212 1 11.412267 -4.310568066 1.83798961 1.058389196 3.149719256 0.986033696 0.06121902 0.072045166 0.26541461 0.010781392 0.249704552 4.89E-05 4.310568066 2.09133006 up DSLIFLVDASK ddPTM_HeLa_Curcumin_4h_R1 1 DSLIFLVDASK 11 0 P12956;P12956-2 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 0 175.86 0.0017512 6094300 1719.6 1538.2 1585.6 1522.1 1143.4 2072.4 1697.5 1408 1544.2 1645.2 FALSE FALSE TRUE 1583.491845 1671.155154 1644.363731 1515.801954 1129.765702 1642.560879 1745.127281 1837.292718 1374.805123 1702.370578 0.930168711 0.981663555 0.96592584 0.890406574 0.663642638 0.964866816 1.025115979 1.079255447 0.807582756 1 10.73332941 -9.174631606 0.633121025 1.007011976 0.931204743 0 0.120371241 2.909756214 1.809458524 0.123493673 0.024909152 6.69E-10 9.174631606 -0.075807233 TAST(ph)PTPPQTGGGLEPQANGETPQVAVIVRPDDR ddPTM_HeLa_Curcumin_4h_R1 1 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDR 34 1 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6;C9JF13;C9J6B6;C9JSU8;C9J556;C9K073;C9J2Z7;C9JWW9;C9JWH7 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 0 T(0.096)AS(0.226)T(0.495)PT(0.169)PPQT(0.012)GGGLEPQANGET(0.001)PQVAVIVRPDDR 42.166 0.0087575 14799000 2146.3 1845.1 2050.3 1763.6 1601.7 1725.7 758.62 327.09 2088.4 1668.4 TRUE FALSE FALSE 1976.41809 2004.582222 2126.285922 1756.30269 1582.600774 1367.770367 779.9048355 426.8182353 1859.307745 1726.376776 1.144835889 1.161149901 1.231646505 1.017334521 0.916718063 0.792278016 0.451758183 0.247233536 1.076999975 1 10.75353165 -4.756062111 1.085971583 1.088515043 0.125056745 0.950220389 0.068112788 0.163538301 0.253179553 0.013200636 0.147400021 1.75E-05 4.756062111 -0.963458298 down DSLLDGHFVLATLSDTDSHSQDLGS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 DSLLDGHFVLATLSDTDSHSQDLGSPER 28 0 Q99638 Q99638 RAD9A Cell cycle checkpoint control protein RAD9A 1 0 DSLLDGHFVLATLS(0.012)DT(0.014)DS(0.046)HS(0.027)QDLGS(0.901)PER 193 5.74E-20 7278600 2308.9 2256.3 2162.7 2194 2551.1 5369.5 2667.7 2529.1 2477.3 2141.8 TRUE FALSE FALSE 2126.148129 2451.324518 2242.851565 2184.921809 2520.679799 4255.805173 2742.548482 3300.210947 2205.546388 2216.227391 0.959354684 1.106079876 1.012013286 0.985874382 1.137374174 1.920292652 1.237485149 1.489112066 0.995180547 1 11.1138902 -5.480045739 10.03761243 0.996374159 1.52016919 0.694951596 0.159610787 0.240608185 55.29624208 0.020676209 0.046017269 3.31E-06 5.480045739 0.523795031 DSLLQDGEFSMDLR ddPTM_HeLa_Curcumin_4h_R1 2 DSLLQDGEFSMDLR 14 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 0 ; ; 121.21 0.0088371 489440000 8098.2 5653.2 7068.1 6263.2 6874.7 9692.4 7291.1 7073.4 7329.1 6741.3 FALSE FALSE TRUE 7457.218925 6141.837418 7330.050004 6237.284538 6792.723693 7682.086984 7495.668643 9230.047098 6525.116067 6975.559673 1.069049549 0.880479518 1.050818909 0.894162595 0.973789059 1.101286111 1.074561611 1.32319807 0.935425453 1 12.76809326 -3.812851635 1.237119339 1.011144981 1.852810097 0.670942306 0.069974661 1.809320555 1.090428516 0.010071369 2.545762605 0.000153868 3.812851635 0.841665116 DSLPVSLS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 DSLPVSLSR 9 0 A0A0X1KG68;Q5XG87-2;Q5XG87 A0A0X1KG68 PAPD7 Non-canonical poly(A) RNA polymerase PAPD7 1 0 DSLPVS(0.007)LS(0.993)R 109.16 0.0094225 2197200 2504.2 1808.5 1942.6 2117.8 1880.6 1875.8 1574.6 985.44 2343.9 1868.8 TRUE FALSE FALSE 2305.989928 1964.818681 2014.594465 2109.037105 1858.175073 1486.737935 1618.779038 1285.89612 2086.780034 1933.740661 1.192502167 1.016071452 1.041812124 1.090651475 0.960922584 0.768840396 0.837123132 0.66497858 1.079141622 1 10.91717861 -5.381149443 1.652428057 1.084654071 0.742195402 0.826901173 0.063802192 0.141822588 0.740879064 0.012415429 0.039038813 4.16E-06 5.381149443 -0.342458669 DSLRDESQR ddPTM_HeLa_Curcumin_4h_R1 1 DSLRDESQR 9 1 Q96MW1;Q86WV7 Q96MW1 CCDC43 Coiled-coil domain-containing protein 43 0 0 96.034 0.013328 20095000 2208.2 1841.4 2179.5 2030.8 1981.4 1912.9 1934.2 2163.8 2115.2 2023 FALSE FALSE TRUE 2033.41864 2000.562411 2260.274187 2022.397088 1957.773099 1516.142977 1988.468446 2823.532659 1883.167852 2093.299099 0.971394217 0.95569831 1.079766474 0.966129058 0.935257221 0.724283968 0.949920844 1.348843393 0.899617189 1 11.03156275 -6.067993785 24.99971544 0.991153978 0.96565385 0 0.149740473 1261.044225 463652.7429 0.021649215 0.035901172 8.55E-07 6.067993785 -0.025500127 RTDALTSS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 1 RTDALTSSPGR 11 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 0 RTDALTS(0.013)S(0.987)PGR 152 0.00023328 484750000 2771.6 2626.5 2743.4 2396.9 3285.2 2680 3023.4 3648.9 2282.1 2104.5 TRUE FALSE FALSE 2552.224935 2853.522957 2845.072817 2386.982263 3246.026136 2124.13779 3108.228467 4761.432813 2031.75934 2177.631218 1.172018896 1.310379339 1.306498912 1.096137051 1.490622521 0.975435038 1.427343822 2.186519358 0.933013507 1 11.08854394 -4.310270658 2.704466949 1.139889499 2.331281321 0.772590429 0.166942939 0.131253899 1.358499818 0.022946768 0.330088031 4.89E-05 4.310270658 1.191391822 up DSLSS(ph)PGNFVLTCQWK ddPTM_HeLa_Curcumin_4h_R1 2 DSLSSPGNFVLTCQWK 16 0 O75815;O75815-3 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 0 DS(0.015)LS(0.371)S(0.613)PGNFVLTCQWK;DS(0.01)LS(0.079)S(0.911)PGNFVLTCQWK ; 116.06 0.0011828 31143000 5384.5 4555.8 5110.4 4722.2 4938.1 7966.6 5326.9 3128 5732.9 4927.7 TRUE FALSE FALSE 4958.311143 4949.583052 5299.79592 4702.660788 4879.216383 6314.237358 5476.358477 4081.7128 5104.015213 5098.937208 0.972420514 0.970708767 1.03939227 0.922282545 0.956908505 1.238343816 1.074019595 0.80050266 1.000995895 1 12.31598086 DSLSVNEFK ddPTM_HeLa_Curcumin_4h_R1 1 DSLSVNEFK 9 0 Q99584 Q99584 S100A13 Protein S100-A13 0 0 107.15 0.0045504 1785600 707.62 589.04 657.12 633.53 458.22 831.63 771.29 709.64 737.3 767.96 FALSE FALSE TRUE 651.6111303 639.9539929 681.4734453 630.9086207 452.7560258 659.1405636 792.9303216 926.0059692 656.4200346 794.6465528 0.820001204 0.805331616 0.857580572 0.793948729 0.569757742 0.829476402 0.997840258 1.165305463 0.826052831 1 9.634169503 -4.468146728 3.065794371 0.863918137 1.161545841 0.475129129 0.109073749 0.251833963 4.187771806 0.018751828 0.139521567 3.40E-05 4.468146728 0.297627704 DSLVEHDEEFVQRQDS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 DSLVEHDEEFVQRQDSPR 18 1 E9PDC2;A0A088AWP5;Q8WUY3-4;Q8WUY3;Q8WUY3-2;Q8WUY3-3 E9PDC2 PRUNE2 Protein prune homolog 2 1 0 DSLVEHDEEFVQRQDS(1)PR 72.09 0.0054649 5099200 807.92 708.15 745.17 778.72 1127.3 964.62 532.25 697.45 978.58 1010.7 TRUE FALSE FALSE 743.9722795 769.3593305 772.7866557 775.497863 1113.857684 764.5469385 547.1835025 910.0992943 871.2322223 1045.82175 0.711375796 0.735650536 0.738927696 0.741520114 1.065055 0.731048994 0.523209144 0.870224103 0.833059957 1 10.03042126 -9.315274322 0.960144972 1.00489828 0.760022809 0.118685285 0.138145289 0.560642049 0.89666603 0.097320847 0.023912142 4.84E-10 9.315274322 -0.24487547 DSLVEHDEEFVQRQDS(ph)PRDNSER ddPTM_HeLa_Curcumin_4h_R1 1 DSLVEHDEEFVQRQDSPRDNSER 23 2 E9PDC2;A0A088AWP5;Q8WUY3-4;Q8WUY3;Q8WUY3-2;Q8WUY3-3 E9PDC2 PRUNE2 Protein prune homolog 2 1 0 DSLVEHDEEFVQRQDS(0.5)PRDNS(0.5)ER 51.611 0.0062846 7439700 1187.4 1346.4 1148.2 1183.5 1212.3 1344 910.53 852.12 1290.8 1268.8 TRUE FALSE FALSE 1093.416037 1462.776817 1190.753302 1178.602991 1197.844114 1065.23925 936.0770212 1111.927465 1149.202469 1312.890706 0.832830968 1.114164957 0.906970624 0.897715998 0.91237154 0.811369328 0.712989297 0.846930716 0.875322268 1 10.35853111 -5.243801547 2.799661609 0.932050978 0.775799028 0.416829321 0.078638357 0.223337432 3.473245235 0.012567166 0.034995347 5.70E-06 5.243801547 -0.15625195 DSLYVDGDCTMDIR ddPTM_HeLa_Curcumin_4h_R1 4 DSLYVDGDCTMDIR 14 0 C9J0J7;G5E9Q6;P35080-2;C9J712;C9JQ45;C9J2N0;P35080 C9J0J7 PFN2 Profilin;Profilin-2 0 0 ;;; ;;; 208.15 1.40E-08 61033000 5562.96 4119.58 4862.75 4960.12 5135.2 5765.31 4206.5 4578.76 5724.89 4678.67 FALSE FALSE TRUE 5122.645846 4475.658139 5042.967793 4939.596338 5073.966094 4569.519718 4324.523069 5974.802846 5096.88389 4841.253434 1.058123875 0.924483339 1.04166573 1.020313521 1.048068679 0.943871206 0.893265169 1.234143787 1.052802535 1 12.2411649 DSNAPKS(ph)PLTGYVR ddPTM_HeLa_Curcumin_4h_R1 1 DSNAPKSPLTGYVR 14 1 H0YNS8;H0YKM5;Q9NP66 H0YNS8 HMG20A High mobility group protein 20A 1 0 DSNAPKS(0.99)PLT(0.01)GYVR 152.68 0.004288 35007000 2121.3 1688.1 1782.6 2190.2 1983.7 2375.6 2230.1 2290.6 2231.3 1679.9 TRUE FALSE FALSE 1953.396867 1834.011842 1848.664724 2181.137533 1960.045673 1882.873781 2292.670604 2988.993395 1986.531972 1738.2764 1.123755041 1.055074925 1.063504472 1.254770261 1.127579983 1.083184344 1.318933286 1.719515605 1.142817087 1 10.76344179 -1.000000051 0.787276604 1.069393083 152.7983446 0.870878551 0.071273417 110.9449772 0.384128199 0.012298546 30006.53502 0.099999988 1.000000051 151.7289515 DSNELS(ph)DSAGEEDSADLKR ddPTM_HeLa_Curcumin_4h_R1 1 DSNELSDSAGEEDSADLKR 19 1 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 0 DS(0.204)NELS(0.503)DS(0.293)AGEEDSADLKR 66.609 0.0058507 4278000 2420.1 2025.6 2207.4 2172.2 1793.2 2398.7 1868.2 1257.1 2590 1976.6 TRUE FALSE FALSE 2228.546531 2200.683838 2289.208186 2163.212012 1771.817261 1901.182581 1920.616664 1640.384003 2305.88348 2045.286703 1.089601046 1.075978167 1.119260289 1.057657104 0.866292857 0.929543315 0.939045201 0.802031324 1.127413324 1 10.99808738 -5.765945466 24.99841103 1.053473842 0.891380462 0.763299678 0.051792345 48.72759094 270327.7808 0.007888057 0.01465653 1.71E-06 5.765945466 -0.162093381 DSNELSDS(ph)AGEEDSADLKR ddPTM_HeLa_Curcumin_4h_R1 1 DSNELSDSAGEEDSADLKR 19 1 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 0 DS(0.107)NELS(0.235)DS(0.658)AGEEDSADLKR 60.8 0.010042 6924100 1613.5 1404.8 1416.5 1463.2 1431.7 1776.5 1226.1 1260.9 1507.5 1425.7 TRUE FALSE FALSE 1485.789772 1526.224652 1468.996736 1457.145666 1414.627913 1408.033875 1260.501066 1645.342606 1342.131022 1475.242969 1.007149198 1.034558161 0.995765963 0.987732663 0.958911815 0.954442017 0.854436247 1.115302794 0.909769475 1 10.52673687 -5.998349794 2.464294042 1.005796566 0.96127992 0 0.067370324 0.484515933 5.906682207 0.008313382 0.015735296 1.00E-06 5.998349794 -0.044516645 DSNNLCLHFNPR ddPTM_HeLa_Curcumin_4h_R1 4 DSNNLCLHFNPR 12 0 P09382 P09382 LGALS1 Galectin-1 0 0 ;;; ;;; 132.86 0.0016785 116449100 11277.3 9023.6 10186.4 8447.5 11847.3 23880.7 14089 13005.4 11950.9 10387 FALSE FALSE TRUE 10384.68981 9803.559776 10563.91694 8412.546483 11706.02869 18927.57363 14484.29942 16970.68659 10639.91617 10747.94748 0.966202136 0.912133205 0.982877612 0.782711909 1.089140853 1.761040763 1.347633997 1.578969997 0.989948657 1 13.39177356 -5.404868917 5.374305913 0.964014008 1.537138429 0.858081034 0.113057837 0.05654432 2.273871135 0.014740987 0.033432931 3.94E-06 5.404868917 0.573124421 DSPAFPDS(ph)PWR ddPTM_HeLa_Curcumin_4h_R1 2 DSPAFPDSPWR 11 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 DSPAFPDS(1)PWR;DSPAFPDS(1)PWR ; 206.46 2.06E-07 33625000 4520 3939.8 3903.3 3937.2 4468.5 5505.9 5873.7 1425.49 4518.7 3904.6 TRUE FALSE FALSE 4162.237231 4280.338757 4047.959732 3920.90891 4415.216056 4363.914276 6038.500214 1860.115339 4023.009915 4040.284559 1.030184179 1.059415171 1.001899661 0.970453653 1.09279829 1.080100723 1.494573 0.460392161 0.995724399 1 11.98024119 -5.747820675 24.55508416 1.014581986 1.068447581 0 0.236002726 976.3107165 1760311.726 0.030316215 0.060358984 1.79E-06 5.747820675 0.053865594 DSPAFPDS(ph)PWRER ddPTM_HeLa_Curcumin_4h_R1 4 DSPAFPDSPWRER 13 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 DSPAFPDS(1)PWRER;DSPAFPDS(1)PWRER;DSPAFPDS(1)PWRER;DSPAFPDS(1)PWRER ;;; 94.487 0.0043144 62510000 16322.4 16001.1 15435.9 16918.7 16112.6 22486.9 15806.1 5657.2 21072.3 15910.2 TRUE FALSE FALSE 15030.46482 17384.16378 16007.96803 16848.6949 15920.46777 17822.86346 16249.57663 7382.054237 18760.72141 16463.07827 0.91298022 1.05594856 0.972355703 1.023423119 0.967040763 1.082596048 0.987031487 0.448400604 1.139563398 1 14.0069465 -4.260978617 24.92454557 0.980003258 0.448400436 0.850732827 0.069860975 8.126959982 439479.2388 0.007613819 0.060158288 5.48E-05 4.260978617 -0.531602822 DSPSVWAAVPGK ddPTM_HeLa_Curcumin_4h_R1 4 DSPSVWAAVPGK 12 0 P07737;CON__P02584;I3L3D5 P07737 PFN1 Profilin-1 0 0 ;;; ;;; 210.27 8.67E-21 89957000 18711.2 14471.1 17550.2 15764.8 17836.2 22401.9 19442.4 17436.8 15605.2 15143.8 FALSE FALSE TRUE 17230.18878 15721.9174 18200.62585 15699.56943 17623.51496 17755.49342 19987.90142 22753.20005 13893.3486 15670.04592 1.099562111 1.003310231 1.161491545 1.001884073 1.124662624 1.133084964 1.275548363 1.452018722 0.886618244 1 13.93572179 -1.000000005 0.548844854 1.044874403 19.91214151 0.787416671 0.070351224 30.10348525 0.25230567 0.00954861 672.2265043 0.099999999 1.000000005 18.8672671 DSQDAGGFGPEDR ddPTM_HeLa_Curcumin_4h_R1 4 DSQDAGGFGPEDR 13 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ;;; ;;; 208.27 5.56E-31 16101800 6905.4 5819.45 5991 6164.9 6489.5 7146.5 5859.7 5385.93 6798.1 6188.1 FALSE FALSE TRUE 6358.830303 6322.457327 6213.03173 6139.391277 6412.116951 5664.235342 6024.107411 7028.075263 6052.365438 6403.136014 0.993080623 0.987400129 0.970310753 0.958810068 1.001402584 0.884603315 0.940805786 1.097598934 0.94521894 1 12.64456294 -6.960563837 2.187534459 0.996873869 0.97014534 0 0.053130159 0.752392365 7.234506605 0.0083576 0.011073905 1.10E-07 6.960563837 -0.026728528 DSQDAS(ph)AEQSDHDDEVASLASASGGFGTK ddPTM_HeLa_Curcumin_4h_R1 2 DSQDASAEQSDHDDEVASLASASGGFGTK 29 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 0 DS(0.05)QDAS(0.623)AEQS(0.327)DHDDEVASLASASGGFGTK;DS(0.055)QDAS(0.555)AEQS(0.386)DHDDEVAS(0.004)LASASGGFGTK ; 83.265 2.94E-06 379935100 4422.7 4522.2 3782.5 4567.9 4497.7 5398.2 3699.4 2086.34 5046.5 4605.3 TRUE FALSE FALSE 4072.638628 4913.078817 3922.682777 4548.99924 4444.067865 4278.55247 3803.195208 2722.455462 4492.911576 4765.333832 0.854638683 1.031004121 0.823170614 0.954602427 0.932582694 0.897849473 0.798096281 0.571304248 0.942832493 1 12.21836157 -4.200053548 1.438201237 0.931442438 0.385467919 0.787825792 0.057470926 0.527023784 0.868037817 0.009525821 0.428666252 6.31E-05 4.200053548 -0.545974519 DSQDASAEQS(ph)DHDDEVASLASASGGFGTK ddPTM_HeLa_Curcumin_4h_R1 4 DSQDASAEQSDHDDEVASLASASGGFGTK 29 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 0 DSQDAS(0.049)AEQS(0.95)DHDDEVASLASASGGFGTK;DS(0.002)QDAS(0.145)AEQS(0.852)DHDDEVASLASASGGFGTK;DSQDAS(0.012)AEQS(0.988)DHDDEVASLASASGGFGTK;DS(0.059)QDAS(0.305)AEQS(0.623)DHDDEVAS(0.011)LAS(0.001)ASGGFGTK ;;; 124.34 1.30E-12 474622100 14170.8 11131.2 11505.3 11934.1 13119.7 15417 10811.6 5685.74 14373.7 12241.2 TRUE FALSE FALSE 13049.16623 12093.33133 11931.69654 11884.71986 12963.25615 12219.34041 11114.9444 7419.295952 12796.94107 12666.58079 1.030204318 0.954743157 0.941982429 0.938273718 1.023421898 0.96469131 0.87750156 0.585737862 1.010291671 1 13.62873952 -4.087887322 1.458233088 0.999662365 0.274288566 0.927720135 0.03329211 0.355495291 0.494838159 0.005618036 0.419457526 8.17E-05 4.087887322 -0.725373798 DSQDGSSYR ddPTM_HeLa_Curcumin_4h_R1 1 DSQDGSSYR 9 0 C9J9W2;Q14847;Q14847-2;Q14847-3;J3KSN1 C9J9W2 LASP1 LIM and SH3 domain protein 1 0 0 92.538 0.017802 420550 594.45 737.89 624.75 449.47 279.99 453.79 350.04 198.89 229.48 492.53 FALSE FALSE TRUE 547.3986552 801.6699236 647.9037846 447.6102122 276.6513021 359.6688387 359.8611803 259.5306454 204.3066181 509.6453808 1.074077537 1.572995565 1.271283541 0.878277777 0.542830981 0.705723729 0.706101132 0.509237708 0.400879957 1 8.993349936 -5.981325031 4.565392641 1.100666549 0.632387381 0.356552 0.280731534 0.111598098 5.826946155 0.029321943 0.052936083 1.04E-06 5.981325031 -0.468279167 DSQQTEFTQNAATGLNIS(ph)RDETVLQEEAR ddPTM_HeLa_Curcumin_4h_R1 1 DSQQTEFTQNAATGLNISRDETVLQEEAR 29 1 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 0 DSQQTEFT(0.014)QNAAT(0.19)GLNIS(0.794)RDET(0.002)VLQEEAR 62.683 0.00061782 6317400 395.58 360.02 275.15 263.09 477.99 425.8 216.65 0 458.92 154.5 TRUE FALSE FALSE 364.2694256 391.1385246 285.347301 262.0014033 472.2902814 337.4842802 222.7286159 0 408.5776242 159.8688635 2.278551418 2.446621037 1.784883528 1.638851979 2.95423556 2.111006939 1.393195717 0 2.555704815 1 7.320745173 -1.889792162 6.372347558 1.708267242 1.425109504 0 0.826616911 0 0 0.111408427 0 0.012888662 1.889792162 -0.283157738 DSQS(ph)PDSAWR ddPTM_HeLa_Curcumin_4h_R1 2 DSQSPDSAWR 10 0 O94875-12;O94875-11;O94875-9;O94875-8;C9J372;C9IZT7;C9JWC3;C9JN77;C9J4Z9;C9JI79;C9JDX2;C9JBB0;C9JZ60;C9JM25;C9JFS9;C9JC90;C9J620 O94875-12 SORBS2 Sorbin and SH3 domain-containing protein 2 1 0 DS(0.017)QS(0.947)PDS(0.036)AWR;DS(0.012)QS(0.898)PDS(0.091)AWR ; 120.59 0.0044646 72925000 5617.7 5092.1 4800.9 4900.6 4845 6366.4 4567.9 4080.5 6553.6 4932.4 TRUE FALSE FALSE 5173.053117 5532.238434 4978.825577 4880.322616 4787.226539 5045.936876 4696.06298 5324.625666 5834.686476 5103.800533 1.013568827 1.083944876 0.975513354 0.95621343 0.937972891 0.988662634 0.920110994 1.043266803 1.143204253 1 12.31735623 -6.546546338 24.99999024 1.013226948 0.96585765 0.250609665 0.056165617 222.1048863 234607.641 0.00565776 0.008001517 2.84E-07 6.546546338 -0.047369298 DSRVS(ph)TSSQESK ddPTM_HeLa_Curcumin_4h_R1 1 DSRVSTSSQESK 12 1 Q6PJT7;Q6PJT7-5;H0YJA2;Q6PJT7-9;Q6PJT7-2;Q6PJT7-3;Q6PJT7-11;Q6PJT7-4;G3V256;A0A3B3IT62;G3V3Y4;G3V3R9;G3V572 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 1 0 DS(0.005)RVS(0.766)T(0.185)S(0.041)S(0.003)QESK 66.059 0.018486 4565100 1246.8 1564.3 1311.7 1502.2 1312.8 1789.2 1202.6 2082.3 1643.3 1542.6 TRUE FALSE FALSE 1148.114464 1699.511122 1360.312756 1495.984294 1297.145717 1418.099752 1236.341719 2717.183684 1463.034101 1596.205235 0.719277471 1.064719676 0.852216699 0.937212998 0.812643443 0.888419434 0.774550598 1.702277141 0.916570168 1 10.64043045 -4.257204054 24.98498902 0.874858251 1.70227747 0.861880128 0.098066349 130.4492263 769515.0495 0.016078242 0.167753393 5.53E-05 4.257204054 0.827419219 DSS(ph)PVGLVEEAGSR ddPTM_HeLa_Curcumin_4h_R1 2 DSSPVGLVEEAGSR 14 0 Q6ICB4 Q6ICB4 FAM109B Sesquipedalian-2 1 0 DS(0.111)S(0.889)PVGLVEEAGSR;DS(0.065)S(0.935)PVGLVEEAGSR ; 144.88 0.00064342 7528500 4236.1 3520.1 3908.4 4069.6 3861.2 5341.1 4084.6 3661.8 4287.9 3721.7 TRUE FALSE FALSE 3900.808215 3824.361759 4053.248742 4052.761074 3815.157712 4233.295653 4199.202883 4778.265963 3817.528098 3851.028798 1.012926265 0.993075347 1.052510629 1.052383996 0.990685324 1.099263567 1.090410668 1.240776482 0.991300844 1 11.9110282 -1 0.576890245 1.007578496 13.28910456 0.870222538 0.026592877 30.25642809 0.232583599 0.004339113 466.6503572 0.1 1 12.28152607 DSS(ph)STDSANEKPALIPR ddPTM_HeLa_Curcumin_4h_R1 1 DSSSTDSANEKPALIPR 17 1 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2;F2Z2S1;C9JKE4;F8VZ02;F8VT91;C9JGM8;C9JW67;F8W6C2 B8ZZZ7 SPATS2L SPATS2-like protein 1 0 DS(0.025)S(0.867)S(0.08)T(0.004)DS(0.025)ANEKPALIPR 195.38 1.01E-06 8421700 3981.6 3214.2 3621.9 3820.2 4129.6 4821.8 3218.8 1866.6 3458.6 3832.6 TRUE FALSE FALSE 3666.452159 3492.021126 3756.1308 3804.393025 4080.357217 3821.704327 3309.110865 2435.717747 3079.200233 3965.782565 0.92452173 0.880537717 0.947134831 0.959304491 1.028890805 0.963669658 0.834415607 0.614183382 0.776442022 1 11.95338986 -4.358742322 2.224072196 0.960713633 0.563997713 0.648374644 0.069695171 0.137093545 0.900886693 0.006450349 0.097832888 4.38E-05 4.358742322 -0.39671592 DSS(ph)TSPGDYVLSVSENSR ddPTM_HeLa_Curcumin_4h_R1 4 DSSTSPGDYVLSVSENSR 18 0 I3L297;P46108-2;P46108 I3L297 CRK Adapter molecule crk 1 0 DS(0.001)S(0.999)TSPGDYVLSVSENSR;DSS(0.5)T(0.5)SPGDYVLSVSENSR;DSS(1)TSPGDYVLSVSENSR;DSS(0.919)T(0.078)S(0.003)PGDYVLSVSENSR ;;; 418.9 0 78628100 5269.7 3899.54 5081.6 4776.9 6189.3 6177.9 5241 5256.2 4253.65 4254.23 TRUE FALSE FALSE 4852.597684 4236.598862 5269.928566 4757.134454 6115.49664 4896.533901 5388.048355 6858.791183 3787.035237 4402.064176 1.102345966 0.962411881 1.197149418 1.08065995 1.389233867 1.112326787 1.223982236 1.558085232 0.86028624 1 12.10396446 -1 0.305428983 1.028501266 4.925647075 0.625569969 0.119528166 22.98062246 0.293915564 0.036875579 49.92122848 0.1 1 3.89714581 DSS(ph)VEVR ddPTM_HeLa_Curcumin_4h_R1 2 DSSVEVR 7 0 O15371-2;O15371-3;O15371;B0QYA6;B0QYA5 O15371-2 EIF3D Eukaryotic translation initiation factor 3 subunit D 1 0 DS(0.292)S(0.708)VEVR;DS(0.096)S(0.904)VEVR ; 111.74 0.015531 145461000 13962.5 16125.1 13648.8 12052 12042.6 14586.9 9895.9 8662.8 12037 13756.2 TRUE FALSE FALSE 12857.35339 17518.88179 14154.63653 12002.13202 11898.99986 11561.41251 10173.55232 11304.04784 10716.57122 14234.22693 0.903270227 1.230757517 0.99440852 0.843188189 0.835942824 0.812226233 0.714724612 0.794145541 0.752873428 1 13.79707652 -6.067911674 2.809633765 0.980669464 0.786321426 0.379609429 0.113905655 0.185626568 2.884989314 0.01491198 0.026911883 8.55E-07 6.067911674 -0.194348038 DSSEATGWEEPS(ph)PPSIR ddPTM_HeLa_Curcumin_4h_R1 1 DSSEATGWEEPSPPSIR 17 0 A0A1B0GU24;Q9HCJ0;Q9HCJ0-2 A0A1B0GU24 TNRC6C Trinucleotide repeat-containing gene 6C protein 1 0 DSSEATGWEEPS(1)PPSIR 156.29 0.00017164 4616700 811.49 644.16 863.34 848.25 972.85 856.98 975.02 405.35 726.13 602 TRUE FALSE FALSE 747.2597102 699.8383201 895.3361399 844.7401663 961.2493991 679.2326878 1002.376437 528.939349 646.4753557 622.9194552 1.19960888 1.123481237 1.437322486 1.356098544 1.54313594 1.090402109 1.609158983 0.849129602 1.037815323 1 9.282901822 -8.033394627 0.646839517 1.021481187 1.318180867 0.197212162 0.213361648 0.663007055 0.624879821 0.081062443 0.053205293 9.26E-09 8.033394627 0.29669968 DSSKGEDS(ph)AEETEAK ddPTM_HeLa_Curcumin_4h_R1 1 DSSKGEDSAEETEAK 15 1 Q12906;Q12906-7;Q12906-5;Q12906-4;Q12906-2;Q12906-6;Q12906-3 Q12906 ILF3 Interleukin enhancer-binding factor 3 1 0 DS(0.013)S(0.014)KGEDS(0.959)AEET(0.014)EAK 113.33 0.017945 9642800 1267 1139.2 1153.7 1576 1201.1 1442.9 1434.9 1090.5 1176 1308.7 TRUE FALSE FALSE 1166.715613 1237.667372 1196.457137 1569.47893 1186.777667 1143.626275 1475.159432 1422.98843 1046.995742 1354.177228 0.861567887 0.913962624 0.883530688 1.158990786 0.876382827 0.844517432 1.089340008 1.05081403 0.773160057 1 10.40320085 DSSLPGDLHVT(ph)S(ph)GPES(ph)PFNNIFNDVDK ddPTM_HeLa_Curcumin_4h_R1 1 DSSLPGDLHVTSGPESPFNNIFNDVDK 27 0 Q8IWU2 Q8IWU2 LMTK2 Serine/threonine-protein kinase LMTK2 3 0 DS(0.072)S(0.072)LPGDLHVT(0.95)S(0.95)GPES(0.956)PFNNIFNDVDK 42.185 0.0083926 0 524.21 427.88 353.49 474.48 344.21 370.37 314.78 368.16 525.39 296.28 TRUE FALSE FALSE 482.7182254 464.8640406 366.5906504 472.5167275 340.1055206 293.5510871 323.6118796 480.4102892 467.7560315 306.5757079 1.574548188 1.516310747 1.195758962 1.541272564 1.109368785 0.957515809 1.055569216 1.567020076 1.525743949 1 8.260099577 DSSPASGTDRDS(ph)PEPLLK ddPTM_HeLa_Curcumin_4h_R1 2 DSSPASGTDRDSPEPLLK 18 1 A6NHT5 A6NHT5 HMX3 Homeobox protein HMX3 1 0 DS(0.009)S(0.011)PAS(0.186)GT(0.186)DRDS(0.607)PEPLLK;DS(0.006)S(0.026)PAS(0.16)GT(0.16)DRDS(0.648)PEPLLK ; 77.221 0.003499 62861000 6169.2 4578.4 5580.9 5809.8 6729.1 8666.7 7015.8 5154.5 5904 5494.9 TRUE FALSE FALSE 5680.90131 4974.136495 5787.733063 5785.760587 6648.859877 6869.128726 7212.644466 6726.083322 5256.345971 5685.847366 0.999130111 0.874827651 1.017919176 1.017572266 1.169370096 1.208109941 1.268525868 1.18295179 0.924461322 1 12.47315966 -5.708020709 2.285341612 0.989583653 1.224706723 0.856111182 0.047323035 0.076419403 0.812176315 0.006414663 0.014129281 1.96E-06 5.708020709 0.23512307 SNVSSPAT(ph)PTASSSSSTTPTR ddPTM_HeLa_Curcumin_4h_R1 1 SNVSSPATPTASSSSSTTPTR 21 0 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 SNVS(0.004)S(0.001)PAT(0.856)PT(0.088)AS(0.036)S(0.015)SSSTTPTR 178.73 2.55E-09 18319000 1632 1009 1192.7 1023.4 1515.8 1500.5 1552.2 1713.9 1236.7 1019.1 TRUE FALSE FALSE 1502.825478 1096.213464 1236.902511 1019.165442 1497.725075 1189.279386 1595.750554 2236.46022 1101.037104 1054.513649 1.425136108 1.039544121 1.172960172 0.966479137 1.420299373 1.12779895 1.513257373 2.120845209 1.0441184 1 10.04236205 -4.302255946 1.979304663 1.184495292 2.354950227 0.782583841 0.156524163 0.279929163 1.235019243 0.025917041 0.574430684 4.99E-05 4.302255946 1.170454935 up RLS(ph)QPESAEK ddPTM_HeLa_Curcumin_4h_R1 3 RLSQPESAEK 10 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 RLS(1)QPESAEK;RLS(0.999)QPES(0.001)AEK;RLS(1)QPESAEK ;; 114.21 0.002716 288491000 10044.7 8232 7988.1 9146.2 10322.4 16044.1 34151 57710 12323 10558.1 TRUE FALSE FALSE 9249.651396 8943.537399 8284.146013 9108.355448 10199.31212 12716.37281 35109.18515 75305.51334 10971.19773 10924.99319 0.846650541 0.818630936 0.758274707 0.833717266 0.933576062 1.163970777 3.213657395 6.892957463 1.004229251 1 13.41534476 -4.300892681 1.691869709 0.890432367 8.723546607 0.997104892 0.099544999 0.035545327 0.10394809 0.016741148 0.438641332 5.00E-05 4.300892681 7.83311424 up DSSS(ph)LSSCTSGILEER ddPTM_HeLa_Curcumin_4h_R1 1 DSSSLSSCTSGILEER 16 0 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 0 DSS(0.07)S(0.897)LS(0.032)SCT(0.001)SGILEER 97.823 0.0034739 9162800 2090.7 2074.8 2122.7 2621.3 2564.4 2860.9 2130.8 1381.5 2717.2 2206.3 TRUE FALSE FALSE 1925.218889 2254.136467 2201.369129 2610.453755 2533.821205 2267.517091 2190.584513 1802.71299 2419.129958 2282.968761 0.843296204 0.987370702 0.964257228 1.143446989 1.109879928 0.993231765 0.959533284 0.789635417 1.059642164 1 11.1566954 -10.0558231 2.715805815 1.00108491 0.949538959 0 0.103715991 1.159990891 15.58282323 0.099696178 0.017054398 8.79E-11 10.0558231 -0.051545951 DSSSSLTDPQVSY(ph)VKSPAAER ddPTM_HeLa_Curcumin_4h_R1 1 DSSSSLTDPQVSYVKSPAAER 21 1 O94887-3;O94887-2;O94887;H7C3M7 O94887-3 FARP2 "FERM, RhoGEF and pleckstrin domain-containing protein 2" 1 0 DSSSS(0.001)LT(0.01)DPQVS(0.319)Y(0.439)VKS(0.23)PAAER 75.319 0.0079691 40474000 4009.6 3104.9 3759 3957 4033.8 4027 2584.9 2017.3 4234.7 3058 TRUE FALSE FALSE 3692.235929 3373.273721 3898.311847 3940.626982 3985.69957 3191.754806 2657.425337 2632.365483 3770.164005 3164.265272 1.166854107 1.066052758 1.2319801 1.245352916 1.259597166 1.008687493 0.839823816 0.831904173 1.191481649 1 11.62765484 -4.891361418 3.684337549 1.11513701 0.834620349 0.670989822 0.087632044 0.13316001 3.419976755 0.015040305 0.05122816 1.28E-05 4.891361418 -0.280516661 DSSSSLTDPQVSYVKS(ph)PAAER ddPTM_HeLa_Curcumin_4h_R1 1 DSSSSLTDPQVSYVKSPAAER 21 1 O94887-3;O94887-2;O94887;H7C3M7 O94887-3 FARP2 "FERM, RhoGEF and pleckstrin domain-containing protein 2" 1 0 DSSSSLTDPQVS(0.002)Y(0.001)VKS(0.997)PAAER 96.41 0.00012213 95751000 7461.8 5876 7304 7774.1 7710.7 6923 4921.9 3837.3 6930.7 5569 TRUE FALSE FALSE 6871.190656 6383.895257 7574.692665 7741.932834 7618.754939 5487.091762 5059.995267 5007.275105 6170.41955 5762.522335 1.192392889 1.107830024 1.314475194 1.343497237 1.322121546 0.952203123 0.878086882 0.868938082 1.070784492 1 12.49248472 -5.058692538 7.349280304 1.144127595 0.88319138 0.56247775 0.11424328 0.198028854 21.95042536 0.020180112 0.052296377 8.74E-06 5.058692538 -0.260936214 DSSSSLTDPQVSYVKS(ph)PAAERR ddPTM_HeLa_Curcumin_4h_R1 1 DSSSSLTDPQVSYVKSPAAERR 22 2 O94887-3;O94887-2;O94887;H7C3M7 O94887-3 FARP2 "FERM, RhoGEF and pleckstrin domain-containing protein 2" 1 0 DSSSSLTDPQVSY(0.002)VKS(0.998)PAAERR 136.77 1.88E-05 34478000 3913.2 2876 3015.6 3155.5 2981.8 3700.5 2502.1 1763.1 3886.7 3228.4 TRUE FALSE FALSE 3603.466091 3124.588625 3127.360789 3142.443377 2946.243982 2932.974587 2572.302192 2300.661074 3460.338734 3340.58666 1.078692594 0.935341287 0.93617113 0.940686082 0.881954065 0.877981889 0.770015106 0.688699713 1.035847618 1 11.70588577 -4.285022947 0.419667757 1.036943229 0.441359448 0.895917445 0.036046563 1.298745585 0.156313202 0.012073074 0.384681463 5.19E-05 4.285022947 -0.595583781 DSTVAVVVYDITNVNSFQQTTKWIDDVR ddPTM_HeLa_Curcumin_4h_R1 1 DSTVAVVVYDITNVNSFQQTTKWIDDVR 28 1 P20340 P20340 RAB6A Ras-related protein Rab-6A 0 0 27.325 0.02022 43683000 4149.2 3909.7 3898.6 3923.2 4486.8 6973.3 4331.2 1004.8 5242.5 3693.6 FALSE FALSE TRUE 3820.786442 4247.637047 4043.085546 3906.966838 4433.29784 5526.958975 4452.721815 1311.158894 4667.410866 3821.952325 0.999694951 1.111378868 1.057858707 1.02224374 1.159956343 1.446108822 1.165038555 0.343059982 1.221211169 1 11.90009407 -7.296329414 18.61382611 0.999855732 1.068005361 0 0.271929235 138.950994 74128.33288 0.043536547 0.049793041 5.05E-08 7.296329414 0.068149629 DSYESYGNSR ddPTM_HeLa_Curcumin_4h_R1 7 DSYESYGNSR 10 0 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 0 0 ;;;;;; ;;;;;; 208.11 6.05E-17 216202400 11150.72 9102.83 8743.41 10308.58 10784.51 12214.61 9885.6 8908.81 11744.4 9903.71 FALSE FALSE TRUE 10268.12875 9889.638064 9067.448466 10265.92583 10655.91176 9681.162199 10162.96333 11625.06516 10456.0687 10247.86319 1.00197754 0.96504392 0.884813575 1.001762576 1.039817918 0.944700571 0.99171536 1.134389184 1.020316969 1 13.3230355 -4.262116037 7.350178678 0.989194814 1.136103853 0.537194781 0.04174741 0.062150602 30.2304781 0.00570742 0.045485556 5.47E-05 4.262116037 0.146909039 DSYGGPPR ddPTM_HeLa_Curcumin_4h_R1 1 DSYGGPPR 8 0 P38159;P38159-2;H3BUY5;Q96E39;H0Y6E7;H3BT71 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 0 0 95.352 0.017668 1990700 1794.1 1675.8 1817.3 1778.1 1803.4 2161.4 1868.7 1759.3 2145.9 1715.1 FALSE FALSE TRUE 1652.095092 1820.648685 1884.650737 1770.742693 1781.895633 1713.101276 1921.130693 2295.702471 1910.500139 1774.699597 0.930915347 1.025891192 1.061954789 0.997770381 1.004054791 0.965290846 1.082510356 1.29357243 1.076520298 1 10.79335913 -4.30998844 2.197944321 0.982136444 1.356722342 0.759990769 0.04651003 0.168313122 0.994254896 0.006211491 0.117558522 4.90E-05 4.30998844 0.374585898 DSYLILETLPTEYDSR ddPTM_HeLa_Curcumin_4h_R1 1 DSYLILETLPTEYDSR 16 0 E9PM69;P17980;E9PMD8;E9PKD5;E9PLG2;E9PN50;R4GNH3 E9PM69;E9PN50 PSMC3 26S protease regulatory subunit 6A 0 0 130.19 0.0039669 5405900 2151.1 2316.8 2129.5 2011.8 2124.3 3161.3 2807.4 2168.6 2330.8 2423.3 FALSE FALSE TRUE 1980.838165 2517.053869 2208.421143 2003.475705 2098.96911 2505.610745 2886.168088 2829.796157 2075.117071 2507.509495 0.789962379 1.003806316 0.880722944 0.798990277 0.837073245 0.999242775 1.151009834 1.128528591 0.827561003 1 11.29203945 -4.943500342 3.437652186 0.893807905 1.139307499 0.676725914 0.072001469 0.132421875 3.182274974 0.012770645 0.042753775 1.14E-05 4.943500342 0.245499595 DSYVGDEAQS(ph)K ddPTM_HeLa_Curcumin_4h_R1 3 DSYVGDEAQSK 11 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle" 1 0 DSYVGDEAQS(1)K;DSYVGDEAQS(1)K;DSYVGDEAQS(1)K ;; 192.4 3.23E-05 87249000 10668.6 9563 9202.5 10133.3 10047.5 10751.8 7804.1 6212.5 10224.1 8459.3 TRUE FALSE FALSE 9824.169053 10389.58311 9543.552745 10091.37109 9927.690125 8521.755482 8023.062042 8106.662651 9102.541809 8753.260045 1.122344018 1.186938701 1.090285527 1.152870021 1.134170592 0.973552189 0.91657988 0.926130677 1.039903049 1 13.09560472 -5.077951025 4.410802738 1.082967024 0.925229864 0.658424073 0.053782754 0.140333448 5.011172678 0.009946123 0.027358217 8.36E-06 5.077951025 -0.15773716 DSYVGDEAQS(ph)KR ddPTM_HeLa_Curcumin_4h_R1 1 DSYVGDEAQSKR 12 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle" 1 0 DSYVGDEAQS(1)KR 90.229 0.0069918 297330000 4825.6 4031.6 4286.5 5035.6 4244.6 4591.4 3231.6 2665.5 4487.1 3314.4 TRUE FALSE FALSE 4443.648668 4380.07354 4445.361461 5014.764021 4193.985917 3639.091884 3322.269999 3478.19868 3994.876356 3429.575153 1.295684879 1.27714756 1.296184297 1.462211439 1.222887888 1.061091162 0.968711823 1.014177711 1.164831263 1 11.74381415 -5.091227742 3.907700736 1.194537125 0.994871072 0.40826054 0.11831739 0.273069217 7.561422029 0.023030418 0.064707264 8.11E-06 5.091227742 -0.199666054 DSYVGDEAQSK ddPTM_HeLa_Curcumin_4h_R1 5 DSYVGDEAQSK 11 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle" 0 0 ;;;; ;;;; 229.53 3.20E-40 1193510000 36657.9 29093.9 31968.9 32093 33576.8 37419.6 31925.7 29540.8 31302.7 27317.6 FALSE FALSE TRUE 33756.38853 31608.64708 33153.69556 31960.20767 33176.41859 29658.35315 32821.44922 38547.65393 27868.87213 28266.88457 1.194202653 1.118221819 1.172881132 1.130659008 1.173685006 1.049226104 1.161127224 1.36370366 0.98591948 1 14.78682526 -9.371265092 0.788795014 0.984533123 1.166313508 0.463840575 0.075930412 0.647288492 0.619387485 0.077705154 0.014507491 4.25E-10 9.371265092 0.181780385 DSYVGDEAQSK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 DSYVGDEAQSKR 12 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle" 0 1 ; DSYVGDEAQSK(1)R;DSYVGDEAQSK(1)R 227.81 1.01E-38 475270000 8420.5 9574.9 6977.9 6786.7 13559.5 19691.4 14078.1 13181 20531.8 8006 FALSE TRUE FALSE 7754.00854 10402.51169 7236.507112 6758.618434 13397.81182 15607.18167 14473.0936 17199.82622 18279.51291 8284.207904 0.935998786 1.255703842 0.87353036 0.815843652 1.617271316 1.883967888 1.747070301 2.076218562 2.206549271 1 13.01614805 -5.621865047 4.048597837 0.975817749 1.871093018 0.322818504 0.412049162 0.044800005 1.364950973 0.019308379 0.040103448 2.39E-06 5.621865047 0.895275269 DSYVGDEAQSKR ddPTM_HeLa_Curcumin_4h_R1 6 DSYVGDEAQSKR 12 1 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle" 0 0 ;;;;; ;;;;; 199.68 3.55E-06 1351565000 27035 21527.7 22546.1 23748.3 20638.4 28077.7 21121.2 23174.2 28495.1 25130.7 FALSE FALSE TRUE 24895.15122 23388.45846 23381.6783 23650.03583 20392.30056 22254.06852 21713.80403 30239.9069 25369.25882 26003.98995 0.9573589 0.89941807 0.899157335 0.909477194 0.784198909 0.855794382 0.835018167 1.162894885 0.97559101 1 14.66644538 -7.524514365 1.227284814 0.987420692 0.895132863 0.098759958 0.094941392 0.562576802 1.701481115 0.019672883 0.02074467 2.99E-08 7.524514365 -0.092287829 PSMS(ph)PTPLDR ddPTM_HeLa_Curcumin_4h_R1 1 PSMSPTPLDR 10 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 PS(0.037)MS(0.927)PT(0.037)PLDR 114.86 0.0055132 52752000 2914.2 2574.9 2536.1 2790.7 2773.7 3008 3300.4 3915.7 2344.6 2008.2 TRUE FALSE FALSE 2683.537995 2797.462882 2630.090097 2779.152823 2740.625439 2384.106893 3393.000341 5109.578904 2087.403246 2077.984801 1.291413678 1.346238376 1.265692654 1.337426925 1.318886182 1.14731681 1.632832127 2.458910625 1.00453249 1 11.02096939 -4.299523834 1.952561718 1.189800918 2.785550455 0.900059981 0.126258966 0.177438084 0.751689621 0.021643964 0.492974464 5.02E-05 4.299523834 1.595749536 up DT(ph)SPSSGSAVSSSK ddPTM_HeLa_Curcumin_4h_R1 4 DTSPSSGSAVSSSK 14 0 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;Q8NEY8-7 F8WF16 PPHLN1 Periphilin-1 1 0 DT(0.912)S(0.088)PSSGSAVSSSK;DT(0.569)S(0.426)PS(0.001)S(0.004)GS(0.001)AVSSSK;DT(0.498)S(0.498)PS(0.004)S(0.001)GSAVSSSK;DT(0.589)S(0.411)PSSGSAVSSSK ;;; 217.2 1.97E-13 2241684700 13065.34 11242.46 11064.13 10782.05 11249.05 12736.3 11097.77 7660.26 12175.9 9504.26 TRUE FALSE FALSE 12031.20455 12214.20815 11474.17639 10737.43673 11114.91243 10094.64781 11409.14356 9995.838011 10840.23423 9834.532328 1.223363161 1.241971427 1.166723135 1.091809593 1.130192271 1.026449197 1.160110433 1.016401968 1.102262301 1 13.26364073 -5.321476801 24.98024605 1.123329441 1.076899092 0.132148581 0.074692356 680.8614688 283290.5319 0.014454979 0.032322318 4.77E-06 5.321476801 -0.046430349 DTAAVVS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 DTAAVVSR 8 0 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 1 0 DTAAVVS(1)R 112.3 0.010625 31236000 2731.5 2513.3 2817.3 2970.9 3549.6 5214.1 4081.2 1591.6 3240.2 2905.9 TRUE FALSE FALSE 2515.298893 2730.538453 2921.711616 2958.607203 3507.273338 4132.636885 4195.707488 2076.871513 2884.758167 3006.879809 0.836514611 0.908096973 0.971675558 0.983945948 1.166416206 1.374393773 1.395369205 0.690706528 0.959385925 1 11.55405149 -5.829202073 3.170865753 0.924382217 1.192351544 0.23640323 0.185270405 0.22769849 4.629671298 0.026863485 0.05272149 1.48E-06 5.829202073 0.267969327 DTASLST(ph)TPSESPR ddPTM_HeLa_Curcumin_4h_R1 1 DTASLSTTPSESPR 14 0 H0YJ30;G3V582;F5H039;Q9NQX3;Q9NQX3-2 H0YJ30 GPHN Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase 1 0 DT(0.007)AS(0.041)LS(0.096)T(0.605)T(0.228)PS(0.024)ESPR 153.81 0.0012352 13005000 2961.8 2473.8 2614.7 2497.8 2803.1 3169.3 2448.5 2226.6 3596.5 2614.3 TRUE FALSE FALSE 2727.370405 2687.624249 2711.603082 2487.464765 2769.674863 2511.951455 2517.19832 2905.48009 3201.972948 2705.14673 1.00821533 0.993522539 1.002386692 0.919530441 1.023853838 0.92858233 0.930521917 1.074056375 1.183659619 1 11.40149113 -6.454062394 24.99993296 1.002961195 0.971725482 0.065108477 0.072283987 286.5169248 104086.4409 0.006196668 0.009465564 3.52E-07 6.454062394 -0.031235713 DTASLSTT(ph)PSESPR ddPTM_HeLa_Curcumin_4h_R1 1 DTASLSTTPSESPR 14 0 H0YJ30;G3V582;F5H039;Q9NQX3;Q9NQX3-2 H0YJ30 GPHN Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase 1 0 DTAS(0.002)LS(0.17)T(0.116)T(0.554)PS(0.08)ES(0.077)PR 108.23 0.0093935 16965000 1912.7 1897.8 1820.6 1953.9 1703.3 2401.7 1534.4 1524.8 2174.1 2086.3 TRUE FALSE FALSE 1761.307777 2061.837376 1888.073038 1945.81528 1682.98926 1903.560347 1577.451134 1989.704501 1935.606669 2158.79877 0.815873995 0.955085488 0.874594272 0.901341666 0.779595247 0.881768312 0.730707816 0.921672056 0.896612828 1 11.07601305 -9.494823746 0.788916217 1.019683747 0.852102627 0.139304223 0.071162238 0.670412635 0.595957584 0.076911218 0.011858748 3.20E-10 9.494823746 -0.16758112 DTCYS(ph)PKPSVYLSTPSSASK ddPTM_HeLa_Curcumin_4h_R1 2 DTCYSPKPSVYLSTPSSASK 20 1 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 0 DT(0.086)CY(0.075)S(0.721)PKPS(0.074)VY(0.022)LS(0.009)T(0.012)PS(0.001)SASK;DT(0.206)CY(0.145)S(0.511)PKPS(0.127)VY(0.008)LS(0.002)T(0.001)PSSASK ; 68.916 0.0030453 135044000 8645.8 6036 6621.8 7177.6 7442.8 6292.6 3925.5 3888.3 7716.7 6282.4 TRUE FALSE FALSE 7961.475807 6557.724944 6867.209733 7147.900993 7354.049471 4987.443828 4035.638965 5073.82477 6870.197316 6500.712932 1.224708104 1.008770117 1.05637794 1.099556474 1.131268147 0.767214901 0.620799443 0.780502819 1.056837517 1 12.66638223 -5.196271732 4.492284786 1.0982155 0.701351922 0.838045216 0.072419889 0.07416072 2.987189203 0.013208883 0.034825593 6.36E-06 5.196271732 -0.396863578 DTDFEHR ddPTM_HeLa_Curcumin_4h_R1 2 DTDFEHR 7 0 P17858;P17858-2 P17858 PFKL "ATP-dependent 6-phosphofructokinase, liver type" 0 0 ; ; 152.47 0.0024319 14692600 14327.3 13864.7 13622.5 13224.6 13830 14898.4 11042.8 9677.9 15220.3 14684.2 FALSE FALSE TRUE 13193.27909 15063.10289 14127.36183 13169.88011 13665.08628 11808.3039 11352.63125 12628.64716 13550.67117 15194.47486 0.868294509 0.991353965 0.929769667 0.866754543 0.899345743 0.777144588 0.747155223 0.831134164 0.891815696 1 13.89125919 -5.56727357 1.237406712 0.940137829 0.776829645 0.633846594 0.047150592 0.258417099 0.761614814 0.009051075 0.029112365 2.71E-06 5.56727357 -0.163308183 DTDSDT(ph)QDANDSSCK ddPTM_HeLa_Curcumin_4h_R1 1 DTDSDTQDANDSSCK 15 0 F8WF49;A0A0B4J2C2;Q9Y2H0-3;Q9Y2H0-1;Q9Y2H0;A0A087WWE6;A0A087X246 F8WF49 DLGAP4 Disks large-associated protein 4 1 0 DTDS(0.27)DT(0.73)QDANDSSCK 203.92 1.47E-30 0 520.1 711.74 569.93 911.99 509.3 772.13 437.67 238.26 796.31 807.6 TRUE FALSE FALSE 478.9335362 773.2596341 591.0521072 908.216427 503.2269301 611.9815343 449.9498423 310.9043772 708.9567853 835.6640399 0.573117321 0.925323572 0.707284362 1.086820042 0.602188088 0.732329627 0.538433893 0.3720447 0.848375365 1 9.706779245 -13.52287875 0.045770894 2.178517666 3.06E-15 0.316018314 0.176982005 551.7279017 2.007446996 89.74217365 24.8706318 3.00E-14 13.52287875 -2.178517666 DTDSEEEIR ddPTM_HeLa_Curcumin_4h_R1 3 DTDSEEEIR 9 0 P0DP25;P0DP24;P0DP23;E7EMB3;A0A590UJC0;G3V226;G3V361;A0A590UJI2;Q96HY3 P0DP25 CALM2;CALM1 0 0 ;; ;; 209.87 3.15E-05 18704700 7737.8 5661.9 7812.5 8025.5 10578.4 9091.7 7509.2 9744.5 6207.9 3897.64 FALSE FALSE TRUE 7125.344965 6151.289407 8102.038123 7992.292607 10452.25949 7205.978935 7719.887942 12715.55319 5526.908901 4033.0827 1.766724239 1.525207853 2.008894616 1.981683293 2.59163034 1.786717375 1.91414075 3.152812411 1.370393149 1 11.97766727 -4.965075204 0.091979148 6.06E-14 4.544876416 0.621942197 0.354665459 20.82587332 0.403733651 5.855053218 15.56539703 1.08E-05 4.965075204 4.544876416 DTDSEEEIREAFR ddPTM_HeLa_Curcumin_4h_R1 7 DTDSEEEIREAFR 13 1 P0DP25;P0DP24;P0DP23;E7EMB3;A0A590UJC0;G3V226;G3V361;A0A590UJI2;Q96HY3 P0DP25 CALM2;CALM1 0 0 ;;;;;; ;;;;;; 169.21 0.00016541 1070735600 14300.11 11445.44 12014.28 14134.7 13506.65 16133.49 12341.5 13972.97 14067.38 10163.91 FALSE FALSE TRUE 13168.2412 12434.73283 12459.53979 14076.21436 13345.59202 12787.22231 12687.76927 18233.26423 12524.22361 10517.10512 1.252078501 1.182334178 1.184692902 1.338411493 1.268941584 1.215850005 1.206393692 1.733677093 1.190843247 1 13.36045003 -1 0.046845467 0.398110306 2.797277521 0.397009341 0.138799968 311.9524666 1.117914603 14.33772918 55.83755981 0.1 1 2.399167216 DTEEPLPVKESDQTLAALLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 DTEEPLPVKESDQTLAALLSPK 22 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 0 DTEEPLPVKESDQTLAALLS(1)PK;DTEEPLPVKESDQT(0.003)LAALLS(0.997)PK;DTEEPLPVKESDQT(0.004)LAALLS(0.996)PK;DTEEPLPVKESDQTLAALLS(1)PK ;;; 126.27 4.15E-06 471313000 10055.8 8161.1 8988.9 9880.5 9012.6 11639.4 9215.7 7028.5 10941.2 8756.9 TRUE FALSE FALSE 9259.872819 8866.509119 9322.036541 9839.617109 8905.130631 9225.257237 9474.267739 9171.457295 9740.977734 9061.201623 1.02192548 0.978513611 1.028785908 1.08590643 0.982775906 1.018105282 1.04558624 1.012167886 1.075020526 1 13.14548667 -9.777276173 0.23673826 0.982244345 1.028357304 0 0.036904402 16.17652002 1.020684062 0.220411721 0.027982244 1.67E-10 9.777276173 0.046112959 DTEFS(ph)T(ph)ISKGAAPSASS(ph)T(ph)PTIIASPK ddPTM_HeLa_Curcumin_4h_R1 1 DTEFSTISKGAAPSASSTPTIIASPK 26 1 P34903 P34903 GABRA3 Gamma-aminobutyric acid receptor subunit alpha-3 4 0 DT(0.273)EFS(0.619)T(0.56)IS(0.278)KGAAPS(0.433)AS(0.433)S(0.678)T(0.677)PT(0.035)IIAS(0.015)PK 43.349 0.0089422 0 517.72 500.32 506.81 377.41 594.05 483.97 405.17 469.24 656.55 326.51 TRUE FALSE FALSE 476.7419157 543.5654314 525.5928244 375.8483774 586.9663417 383.5891665 416.5379797 612.3091159 584.5281076 337.8561982 1.411079383 1.60886624 1.555670215 1.112450739 1.737325954 1.13536223 1.232885417 1.812336489 1.730109173 1 8.400265512 -8.952870391 0.775241355 0.998282283 1.439055947 0 0.318882738 0.560669205 0.620055747 0.142343256 0.044910964 1.11E-09 8.952870391 0.440773663 DTGK(ac)TPVEPEVAIHR ddPTM_HeLa_Curcumin_4h_R1 2 DTGKTPVEPEVAIHR 15 1 P60866;P60866-2;E5RIP1;E5RJX2 P60866 RPS20 40S ribosomal protein S20 0 1 ; DTGK(1)TPVEPEVAIHR;DTGK(1)TPVEPEVAIHR 131.72 0.00074486 116347000 8914.3 7633 6784.2 7718.4 8349.6 11316.5 8221 9030.5 10973.7 6501.8 FALSE TRUE FALSE 8208.723749 8292.762508 7035.62842 7686.463306 8250.036473 8969.330337 8451.659134 11783.85788 9769.912565 6727.737066 1.220131475 1.232622861 1.045764475 1.142503524 1.226272132 1.333186813 1.256240999 1.751533653 1.452184066 1 12.71590561 -1 0.581831884 1.1107772 34.03686125 0.540914576 0.137916689 51.55880069 0.390120631 0.018587081 2153.421648 0.1 1 32.92608405 DTGKTPVEPEVAIHR ddPTM_HeLa_Curcumin_4h_R1 3 DTGKTPVEPEVAIHR 15 1 P60866;P60866-2;E5RIP1;E5RJX2 P60866 RPS20 40S ribosomal protein S20 0 0 ;; ;; 77.192 0.0048945 33741300 28199 21579 23500 25750.8 22748.6 31458.5 22046.7 20843.6 30814.5 26240.4 FALSE FALSE TRUE 25967.01939 23444.19261 24370.93067 25644.25001 22477.3378 24933.65249 22665.27107 27198.71769 27434.22644 27152.25195 0.956348646 0.863434556 0.897565724 0.944461257 0.827825915 0.918290407 0.834747376 1.001711303 1.01038494 1 14.72878424 -7.538991897 2.329949347 0.983811559 0.895745993 0.406690344 0.05011805 0.195624113 2.146800122 0.008609921 0.00923682 2.89E-08 7.538991897 -0.088065565 DTGS(ph)PPASEGPTDGSR ddPTM_HeLa_Curcumin_4h_R1 2 DTGSPPASEGPTDGSR 16 0 Q969R8 Q969R8 ITFG2 Integrin-alpha FG-GAP repeat-containing protein 2 1 0 DT(0.089)GS(0.909)PPAS(0.002)EGPTDGSR;DT(0.005)GS(0.988)PPAS(0.005)EGPT(0.001)DGS(0.001)R ; 115.26 0.0012324 29019000 4348.3 4429.5 3540.6 4194 3697.6 4533.8 3943.7 3804.5 4575.8 4229.5 TRUE FALSE FALSE 4004.127467 4812.366243 3671.817751 4176.646339 3653.508535 3593.438774 4054.349608 4964.474536 4073.846188 4376.47481 0.914920716 1.099598753 0.838989806 0.954340313 0.834806252 0.821080648 0.926396194 1.134354647 0.930851054 1 12.09555355 DTHDQLSEPSEVR ddPTM_HeLa_Curcumin_4h_R1 2 DTHDQLSEPSEVR 13 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 163.51 8.02E-06 10022600 5586 4756.6 5054.2 4696.2 6115.2 6376.4 5349.4 4193 6002.7 5011.4 FALSE FALSE TRUE 5143.862206 5167.739309 5241.513098 4676.768369 6042.280234 5053.862763 5499.489767 5471.426398 5344.218828 5185.545777 0.991961585 0.996566134 1.010792947 0.901885466 1.16521587 0.974605756 1.060542131 1.055130286 1.030599103 1 12.34028012 -5.771407251 24.99998466 0.991466704 1.057259301 0.318979202 0.053413747 184.8787428 463686.5612 0.006878177 0.012576876 1.69E-06 5.771407251 0.065792596 DTHEDHDT(ph)STENT(ph)DESNHDPQFEPIVSLPEQEIK ddPTM_HeLa_Curcumin_4h_R1 1 DTHEDHDTSTENTDESNHDPQFEPIVSLPEQEIK 34 0 P43487-2;P43487;C9JJ34 P43487-2 RANBP1 Ran-specific GTPase-activating protein 2 0 DT(0.006)HEDHDT(0.396)S(0.396)T(0.396)ENT(0.446)DES(0.36)NHDPQFEPIVS(0.001)LPEQEIK 65.33 4.25E-05 11495000 3455.1 2539 2763.9 2652.4 4523.6 6658.3 3966.9 2298.2 4739.8 3078.8 TRUE FALSE FALSE 3181.625189 2758.459846 2866.332565 2641.425072 4469.659024 5277.293525 4078.200538 2998.9106 4219.855798 3185.788071 0.998693296 0.865864202 0.89972481 0.82912768 1.402999486 1.65651117 1.280122986 0.941340269 1.324587733 1 11.63743458 -5.753991533 24.99998082 0.969296214 1.341396908 0.38039274 0.207392475 108.3612038 363729.8057 0.025769173 0.050734503 1.76E-06 5.753991533 0.372100694 DTHEDHDTS(ph)TENTDESNHDPQFEPIVSLPEQEIK ddPTM_HeLa_Curcumin_4h_R1 1 DTHEDHDTSTENTDESNHDPQFEPIVSLPEQEIK 34 0 P43487-2;P43487;C9JJ34 P43487-2 RANBP1 Ran-specific GTPase-activating protein 1 0 DT(0.003)HEDHDT(0.276)S(0.283)T(0.283)ENT(0.086)DES(0.068)NHDPQFEPIVS(0.002)LPEQEIK 47.647 0.0035626 6579300 1520.6 1427.1 666.57 745.28 2048 3346.8 1124.6 788.85 1330.9 657.17 TRUE FALSE FALSE 1400.242905 1550.452165 691.2736706 742.1962288 2023.578938 2652.635954 1156.153249 1029.366734 1184.9036 680.0066086 2.059160731 2.280054554 1.016569048 1.091454435 2.975822458 3.900897315 1.700208843 1.513759897 1.742488359 1 9.409404957 -10.12584211 0.246221271 2.98E-13 2.322334523 0.083766538 0.844346556 11.84362063 0.672684844 8.391533452 0.731978181 7.48E-11 10.12584211 2.322334523 DTHEDHDTSTENT(ph)DESNHDPQFEPIVSLPEQEIK ddPTM_HeLa_Curcumin_4h_R1 1 DTHEDHDTSTENTDESNHDPQFEPIVSLPEQEIK 34 0 P43487-2;P43487;C9JJ34 P43487-2 RANBP1 Ran-specific GTPase-activating protein 1 0 DT(0.001)HEDHDT(0.18)S(0.18)T(0.18)ENT(0.224)DES(0.224)NHDPQFEPIVS(0.01)LPEQEIK 57.613 0.00049004 15877000 1040.4 930.67 596.72 810.95 1394.1 2216.3 1077 559.27 912.63 698.7 TRUE FALSE FALSE 958.0512422 1011.112968 618.8349681 807.5945038 1377.476268 1756.614397 1107.217721 729.7888484 812.5167723 722.979773 1.325142525 1.398535624 0.855950597 1.117036097 1.905276357 2.429686781 1.531464313 1.009418072 1.123844404 1 9.497811475 -5.768183076 24.86307059 1.150450348 1.756334852 0.3852776 0.358788448 116.9755024 431274.1243 0.054907496 0.101183517 1.71E-06 5.768183076 0.605884504 DTIIDVVGAPLT(ph)PNSR ddPTM_HeLa_Curcumin_4h_R1 3 DTIIDVVGAPLTPNSR 16 0 Q9NPF5 Q9NPF5 DMAP1 DNA methyltransferase 1-associated protein 1 1 0 DTIIDVVGAPLT(1)PNSR;DTIIDVVGAPLT(1)PNSR;DTIIDVVGAPLT(0.999)PNS(0.001)R ;; 249.86 1.68E-39 192444700 17335.5 14466.9 16459.4 17481.1 17813.2 20888.6 19051 10315.73 17125.9 14774.9 TRUE FALSE FALSE 15963.37688 15717.35437 17069.39984 17408.76784 17600.78922 16556.0689 19585.51979 13460.94859 15247.23162 15288.32668 1.044154617 1.028062437 1.116498895 1.138696746 1.151256746 1.082922235 1.281076746 0.880472329 0.997311998 1 13.90014289 -6.770746962 5.34595006 1.021672296 1.118865042 0.180348955 0.093515527 0.196101072 16.56511924 0.013388129 0.018250602 1.70E-07 6.770746962 0.097192746 DTIIDVVGAPLT(ph)PNSRK ddPTM_HeLa_Curcumin_4h_R1 1 DTIIDVVGAPLTPNSRK 17 1 Q9NPF5 Q9NPF5 DMAP1 DNA methyltransferase 1-associated protein 1 1 0 DTIIDVVGAPLT(0.93)PNS(0.07)RK 105.52 0.00076983 17448000 3260.9 2808.8 2420.9 2945.7 2507 3326.1 3074.7 1921.5 3082.7 2965.5 TRUE FALSE FALSE 3002.796324 3051.580156 2510.620684 2933.511474 2477.105662 2636.229367 3160.967807 2507.356505 2744.535523 3068.550904 0.978571455 0.994469459 0.818177948 0.955992443 0.807255848 0.859112151 1.030117442 0.817114196 0.894407689 1 11.5833418 -6.786972038 24.98925999 0.989942386 0.88708127 0.228754214 0.071682187 165.5564555 162032.4169 0.00973819 0.012801085 1.63E-07 6.786972038 -0.102861116 DTLRTPPRER ddPTM_HeLa_Curcumin_4h_R1 1 DTLRTPPRER 10 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 0 66.19 0.018866 6460400 3761.9 3052.9 3223 2963.2 3389.5 3647.2 3091.5 2463.7 3276.7 2787 FALSE FALSE TRUE 3464.141645 3316.779073 3342.447215 2950.939064 3349.082426 2890.729608 3178.23917 3214.870789 2917.254208 2883.848043 1.201221976 1.150122691 1.159023349 1.023264409 1.161324167 1.002386244 1.102082746 1.114785086 1.011583885 1 11.49377943 -3.266542136 2.880196814 1.098718259 3.308263248 0 0.072821335 3480.192193 229.569413 0.011924622 49766.06842 0.000541325 3.266542136 2.20954499 DTNGSQFFITTVK ddPTM_HeLa_Curcumin_4h_R1 2 DTNGSQFFITTVK 13 0 P23284 P23284 PPIB Peptidyl-prolyl cis-trans isomerase B 0 0 ; ; 249.98 2.66E-50 3933300 2156.71 1302.72 1892.81 1540.28 1894.58 4230.7 2602.46 2782.6 1685.26 1807.39 FALSE FALSE TRUE 1986.004128 1415.321312 1962.959204 1533.906729 1871.988371 3353.20513 2675.478023 3631.00193 1500.391194 1870.196668 1.06192261 0.756776726 1.049600418 0.820184719 1.000958029 1.792969257 1.430586456 1.941508074 0.802263858 1 10.86897428 -5.266978661 24.52812174 0.992763995 1.692577799 0.826888025 0.16449344 94.81527726 419846.4108 0.020350793 0.046766652 5.41E-06 5.266978661 0.699813805 DTPGHGSGWAET(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 DTPGHGSGWAETPR 14 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 DTPGHGS(0.001)GWAET(0.999)PR;DTPGHGS(0.001)GWAET(0.999)PR ; 107.63 0.0031658 9997900 2434.55 1913.66 2266.69 2250.25 2758.58 4559.7 2401.32 1633.17 2530.33 2353.41 TRUE FALSE FALSE 2241.852799 2079.068243 2350.695525 2240.939062 2725.685735 3613.966822 2468.694576 2131.116015 2252.75913 2435.190822 0.920606623 0.853759888 0.965302392 0.920231401 1.119290411 1.484058986 1.013758164 0.875133068 0.925085258 1 11.24981911 -5.720448231 6.922666641 0.950168752 1.142393179 0.279421006 0.14815057 0.208518019 26.24869234 0.021625555 0.043079638 1.90E-06 5.720448231 0.192224426 DTPRPDHPPHDGHS(ph)PASR ddPTM_HeLa_Curcumin_4h_R1 2 DTPRPDHPPHDGHSPASR 18 1 Q9C0J8 Q9C0J8 WDR33 pre-mRNA 3 end processing protein WDR33 1 0 DTPRPDHPPHDGHS(0.948)PAS(0.052)R;DTPRPDHPPHDGHS(0.714)PAS(0.286)R ; 82.406 0.0015863 12310100 1770.83 1157.56 1423.55 1583.66 1431.05 1954.43 1580.02 1032.09 2152.26 1572.78 TRUE FALSE FALSE 1630.666937 1257.614328 1476.308015 1577.107235 1413.985663 1549.059187 1624.351109 1346.76949 1916.162463 1627.433988 1.001986532 0.772759041 0.907138493 0.969076009 0.868843636 0.951841487 0.998105681 0.827541701 1.177413325 1 10.66838331 -7.416313256 24.0802544 1.000952053 0.905558831 0.379600481 0.084235118 18.32789321 4130.695515 0.010309461 0.011789283 3.83E-08 7.416313256 -0.095393223 DTPTSAGPNS(ph)FNK ddPTM_HeLa_Curcumin_4h_R1 2 DTPTSAGPNSFNK 13 0 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 0 DTPTS(0.001)AGPNS(0.999)FNK;DTPT(0.033)S(0.271)AGPNS(0.696)FNK ; 164.7 0.00017582 11346000 2399.37 2129.32 2352.18 2323.18 2780.67 2685.99 2232.23 2329.01 2680.78 2177.52 TRUE FALSE FALSE 2209.457333 2313.368933 2439.35386 2313.567297 2747.512326 2128.885397 2294.860366 3039.114428 2386.705141 2253.188658 0.980591361 1.026708937 1.082622998 1.026796974 1.219388495 0.944832289 1.018494549 1.348806021 1.059256682 1 11.1377524 -4.26171844 8.045356994 1.015035918 1.351420021 0.59415581 0.074094413 0.043708379 35.4235543 0.010138511 0.079940955 5.47E-05 4.26171844 0.336384103 DTQSGSLLFIGR ddPTM_HeLa_Curcumin_4h_R1 2 DTQSGSLLFIGR 12 0 P50454;E9PKH2;H0YEP8 P50454 SERPINH1 Serpin H1 0 0 ; ; 167.2 1.65E-06 5808800 1679.43 1329.71 1553.47 1542.22 1812.18 2193.61 1475.5 914.36 1532.84 1419.13 FALSE FALSE TRUE 1546.501343 1444.644207 1611.042965 1535.838702 1790.570937 1738.630559 1516.898559 1193.144155 1364.691287 1468.444662 1.053156025 0.983792066 1.097108394 1.045894845 1.219365621 1.183994606 1.032996747 0.812522382 0.929344716 1 10.52007318 -8.411080645 0.589083616 1.002355043 1.066784881 0.069845566 0.107828149 2.212270588 1.624870217 0.065894107 0.029300235 3.88E-09 8.411080645 0.064429838 DTS(ph)GLER ddPTM_HeLa_Curcumin_4h_R1 1 DTSGLER 7 0 Q9H307 Q9H307 PNN Pinin 1 0 DT(0.044)S(0.956)GLER 109.44 0.016172 198880000 7914.8 8108.7 7467.6 6443.5 7391.7 8325.4 6505.4 4767.8 7426.7 7477.8 TRUE FALSE FALSE 7288.335228 8809.579896 7744.355825 6416.838504 7303.558805 6598.618193 6687.924016 6221.480272 6612.009591 7737.652993 0.941931001 1.138533856 1.000866262 0.829300372 0.943898468 0.852793244 0.864334963 0.804052634 0.854523923 1 12.91768032 -6.267836367 24.41356806 0.988897553 0.863564761 0.430792087 0.073624409 242.0055975 923593.8442 0.009768333 0.015153528 5.40E-07 6.267836367 -0.125332792 DTS(ph)PSSGSAVSSSK ddPTM_HeLa_Curcumin_4h_R1 1 DTSPSSGSAVSSSK 14 0 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;Q8NEY8-7 F8WF16 PPHLN1 Periphilin-1 1 0 DT(0.211)S(0.779)PS(0.002)S(0.006)GS(0.002)AVSSSK 126.56 0.0012426 1578500000 3374.5 3630.4 3686.4 3428.5 3745 4276.7 3446.8 2564.1 4253.8 3600 TRUE FALSE FALSE 3107.404764 3944.195599 3823.021227 3414.313775 3700.343321 3389.664212 3543.507931 3345.882286 3787.168782 3725.099732 0.834180287 1.058816108 1.026286946 0.916569762 0.993354162 0.909952607 0.951251828 0.898199384 1.016662386 1 11.86306334 -4.252061222 21.24726141 0.941481982 0.898199201 0 0.067786561 565.8267238 1281693.552 0.010774294 0.158322273 5.60E-05 4.252061222 -0.043282781 DTS(ph)S(ph)RVIQSVTS(ph)YT(ph)KGDLDFTY(ph)VTSR ddPTM_HeLa_Curcumin_4h_R1 1 DTSSRVIQSVTSYTKGDLDFTYVTSR 26 2 S4R305;O75061-3;O75061-4;O75061;O75061-2 S4R305 DNAJC6 Putative tyrosine-protein phosphatase auxilin 5 0 DT(0.516)S(0.533)S(0.541)RVIQS(0.358)VT(0.276)S(0.751)Y(0.046)T(0.4)KGDLDFT(0.409)Y(0.475)VT(0.366)S(0.33)R 44.969 0.010052 5199900 1117.1 910.35 1033.1 1383.7 1516.9 478.03 583.13 820.39 1581.6 833.07 TRUE FALSE FALSE 1028.680356 989.0365976 1071.387595 1377.974616 1498.811958 378.8811895 599.4910584 1070.523134 1408.102437 862.0191205 1.193338212 1.147348793 1.242881474 1.598542983 1.738722405 0.439527593 0.695449839 1.241878642 1.633493276 1 9.75157606 -5.241354732 24.99555388 1.185602877 0.782601876 0.305614025 0.324430257 893.6440098 1112147.764 0.044108662 0.112299902 5.74E-06 5.241354732 -0.403001002 DTSATSQSVNGS(ph)PQAEQPSLESTSK ddPTM_HeLa_Curcumin_4h_R1 2 DTSATSQSVNGSPQAEQPSLESTSK 25 0 C9J0I9;Q86WB0;Q86WB0-2;Q86WB0-3;F8WAU5 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 DTSATSQSVNGS(1)PQAEQPSLESTSK;DTSATSQSVNGS(1)PQAEQPSLESTSK ; 183.79 5.84E-15 39399000 11418.4 9659.4 10215.4 10979 10806 11376.9 10337.2 8493.2 10622.1 9055.9 TRUE FALSE FALSE 10514.62159 10494.31549 10593.99171 10933.57181 10677.14551 9017.202696 10627.23401 11082.73758 9456.882205 9370.591851 1.122087245 1.119920242 1.130557373 1.16679629 1.139431284 0.962287424 1.134104887 1.182714791 1.009208634 1 13.19392446 -9.142198666 0.771146676 0.995189211 1.118105033 0.396922048 0.056503671 0.624670563 0.633865671 0.046842593 0.01172912 7.21E-10 9.142198666 0.122915822 APS(ph)PTLGSPR ddPTM_HeLa_Curcumin_4h_R1 2 APSPTLGSPR 10 0 Q9ULI4;C9JFF0 Q9ULI4 KIF26A Kinesin-like protein KIF26A;Kinesin-like protein 1 0 APS(0.698)PT(0.301)LGS(0.001)PR;APS(0.61)PT(0.388)LGS(0.001)PR ; 102.05 0.011218 41665000 4463.1 3235.8 3308.4 3921.7 3841.4 3989.3 2060.1 1200.85 4198.2 3217.5 TRUE FALSE FALSE 4109.840926 3515.488134 3431.012214 3905.473045 3795.593814 3161.874211 2117.900862 1566.983637 3737.667963 3329.307886 1.234443033 1.055921607 1.03054819 1.173058539 1.140054914 0.949709165 0.636138481 0.47066348 1.122656147 1 11.70100658 -4.753687754 2.058099622 1.109367609 0.473805472 0.91815478 0.066188277 0.093623938 0.730648048 0.013353326 0.076712012 1.76E-05 4.753687754 -0.635562137 down DTSIQEVVSRPSSK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 DTSIQEVVSRPSSKR 15 2 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 0 1 DTSIQEVVSRPSSK(1)R 84.759 0.0053874 4106600 220.14 240.74 173.52 0 188.15 325.54 305.66 259.03 205.47 274.81 FALSE TRUE FALSE 202.7156867 261.5484929 179.9508038 0 185.9064341 258.0193344 314.235997 338.0070546 182.9304551 284.359627 0.712884909 0.919780686 0.632828245 0 0.653772253 0.907369788 1.105065442 1.188660493 0.643306706 1 8.151572838 -9.255251655 0.902973629 1.005330779 0.750496797 0 0.328389496 1.467641472 2.074512246 0.252842516 0.063533865 5.56E-10 9.255251655 -0.254833982 DTSLYRPALEELRR ddPTM_HeLa_Curcumin_4h_R1 1 DTSLYRPALEELRR 14 2 Q13200;C9JPC0;H7C2Q3 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 0 0 71.558 0.011844 38470000 2348.3 1695.6 1866.3 2185.5 1905.8 3040 2392.4 2212 2384.3 2476.5 FALSE FALSE TRUE 2162.429577 1842.160109 1935.46672 2176.45698 1883.07458 2409.469732 2459.524305 2886.428617 2122.748255 2562.558191 0.843855794 0.718875425 0.755286934 0.849329778 0.734841685 0.940259519 0.959792567 1.126385589 0.828370752 1 11.32336905 -4.318896017 1.80372094 0.87891061 1.186465832 0.450865814 0.091486294 0.750557691 2.669353394 0.016457005 0.375424968 4.80E-05 4.318896017 0.307555222 DTSQSDKDLDDALDKLS(ph)DSLGQR ddPTM_HeLa_Curcumin_4h_R1 1 DTSQSDKDLDDALDKLSDSLGQR 23 2 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E9PCH5;P20810-3;E7EQ12;E7EQA0;H0Y7F0;A0A0C4DGD1 P20810-6 CAST Calpastatin 1 0 DTSQSDKDLDDALDKLS(0.995)DS(0.005)LGQR 94.957 9.12E-05 7973300 1310.1 1337.7 1458.2 1313.6 1606.4 1467.4 1378.2 1282.4 1211.8 990.73 TRUE FALSE FALSE 1206.404203 1453.324827 1512.242175 1308.164671 1587.244729 1163.044699 1416.868583 1673.397857 1078.868572 1025.157794 1.176798547 1.417659639 1.47513113 1.276061772 1.548293091 1.134503104 1.382098045 1.632331985 1.052392693 1 10.00163027 -7.638611991 1.107111984 1.045930397 1.404954859 0.562470421 0.135056403 0.223403468 0.564054252 0.030750569 0.030390412 2.30E-08 7.638611991 0.359024462 DTSQSDKDLDDALDKLSDSLGQR ddPTM_HeLa_Curcumin_4h_R1 2 DTSQSDKDLDDALDKLSDSLGQR 23 2 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E9PCH5;P20810-3;E7EQ12;E7EQA0;H0Y7F0;A0A0C4DGD1 P20810-6 CAST Calpastatin 0 0 ; ; 58.796 0.0034578 41230000 2797.3 2460.9 2522.8 2735.8 2824.7 3196.3 2915.1 2638.3 2755.7 2480.29 FALSE FALSE TRUE 2575.890753 2673.60923 2616.297187 2724.479984 2791.017297 2533.35135 2996.88986 3442.705525 2453.406604 2566.479893 1.003666836 1.04174174 1.019410748 1.061562957 1.087488472 0.987091836 1.167704399 1.341411454 0.955942266 1 11.32557524 -4.430582199 2.165127511 1.014909495 1.374424047 0.877106131 0.037758776 0.10073572 0.68131367 0.004995996 0.060443846 3.71E-05 4.430582199 0.359514552 DTSSS(ph)PTTGSTVQSVDLIFTR ddPTM_HeLa_Curcumin_4h_R1 1 DTSSSPTTGSTVQSVDLIFTR 21 0 P57060 P57060 RWDD2B RWD domain-containing protein 2B 1 0 DTS(0.001)S(0.218)S(0.72)PT(0.029)T(0.031)GSTVQSVDLIFTR 187.04 1.31E-10 10874000 2391.7 2486.7 2196.1 2847.6 2044 2535.4 2298.5 2586.6 2942.7 2739.5 TRUE FALSE FALSE 2202.394421 2701.639267 2277.489398 2835.817386 2019.626635 2009.52946 2362.989724 3375.242433 2619.893172 2834.697421 0.776941625 0.953060897 0.803432981 1.000395091 0.712466389 0.708904395 0.833595045 1.190688787 0.924223218 1 11.46897903 -9.554555096 1.315420276 1.000247119 0.85388595 0.03944014 0.14121976 0.737143695 2.279104309 0.096074524 0.02253321 2.79E-10 9.554555096 -0.14636117 DTSSSPT(ph)TGSTVQSVDLIFTR ddPTM_HeLa_Curcumin_4h_R1 1 DTSSSPTTGSTVQSVDLIFTR 21 0 P57060 P57060 RWDD2B RWD domain-containing protein 2B 1 0 DTS(0.004)S(0.027)S(0.088)PT(0.83)T(0.048)GS(0.002)T(0.001)VQSVDLIFTR 127.03 4.60E-05 20669000 2226.8 1966 1897.2 2268 2412.4 2522.9 2083.2 1889.7 2442.5 2126.7 TRUE FALSE FALSE 2050.54643 2135.93228 1967.511901 2258.615617 2383.633706 1999.622101 2141.648985 2465.860831 2174.563861 2200.602667 0.931811299 0.97061242 0.894078668 1.026362301 1.083173142 0.908670216 0.973210211 1.120538872 0.988167421 1 11.10368297 GQPEGPLPSSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 GQPEGPLPSSSPR 13 0 H3BMQ0;A0A2R8YDR3;A0A2R8Y7X5;P49815-3;P49815-5;A0A2R8Y6C9;A0A2R8Y5F1;P49815;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDZ2;A0A2R8YGU4;X5D2U8;P49815-2;P49815-6;P49815-7;P49815-4;H3BQK4 H3BMQ0 TSC2 Tuberin 1 0 GQPEGPLPSS(0.228)S(0.772)PR;GQPEGPLPSS(0.029)S(0.971)PR ; 191.63 7.11E-06 184108000 12062.6 10023.1 10002.9 10794.9 9641.2 9507.5 3997.3 1418.53 11081.6 10051.8 TRUE FALSE FALSE 11107.83248 10889.4521 10373.61627 10750.23356 9526.234987 7535.537328 4109.45348 1851.033267 9865.976205 10401.0993 1.067947931 1.046952037 0.99735768 1.033567054 0.915887322 0.724494316 0.395097995 0.177965157 0.948551294 1 13.3444484 -4.75063622 1.164422534 1.033525389 0.069178277 0.985536049 0.035040226 0.049860766 0.092419678 0.004486609 0.047102434 1.78E-05 4.75063622 -0.964347112 down DTTS(ph)PMELAALEK ddPTM_HeLa_Curcumin_4h_R1 1 DTTSPMELAALEK 13 0 Q6VY07-2;Q6VY07 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 0 DT(0.001)T(0.037)S(0.962)PMELAALEK 102.33 0.0068167 8895700 4792.5 4438.2 4406 4583.1 4370.3 6186.8 4780 4442.1 4393.2 3394 TRUE FALSE FALSE 4413.168568 4821.818232 4569.290236 4564.136347 4318.187027 4903.58794 4914.113935 5796.475841 3911.276951 3511.941247 1.256617995 1.372978046 1.301072516 1.299604983 1.229572684 1.396261382 1.399258584 1.650504787 1.113707968 1 11.77805299 -3.814974651 0.043028579 9.86E-15 3.005568174 0.738258596 0.085425697 106.7411508 0.640215774 15.61707181 31.38805302 0.000153118 3.814974651 3.005568174 DTTSDKDDSLGS(ph)QQTNEQCAQK ddPTM_HeLa_Curcumin_4h_R1 1 DTTSDKDDSLGSQQTNEQCAQK 22 1 P23497;E9PHV6;P23497-7;P23497-6;P23497-2;P23497-3;P23497-4;P23497-5 P23497 SP100 Nuclear autoantigen Sp-100 1 0 DTTSDKDDS(0.004)LGS(0.708)QQT(0.288)NEQCAQK 100.23 0.00016266 0 1595.7 1215.2 1543.5 1570.1 1492 1703.4 1918.9 1552 1193.4 1286.8 TRUE FALSE FALSE 1469.398661 1320.236473 1600.703468 1563.603342 1474.208874 1350.095639 1972.73917 2025.197655 1062.487006 1331.516204 1.10355297 0.991528657 1.202165969 1.174302902 1.107165553 1.013953592 1.481573535 1.520971092 0.797952742 1 10.37885427 -4.755406376 24.73484015 1.067972611 1.501272614 0.731433944 0.109171823 33.8815532 138906.7892 0.010623972 0.037751014 1.76E-05 4.755406376 0.433300003 DTVDPVQDEMLAR ddPTM_HeLa_Curcumin_4h_R1 1 DTVDPVQDEMLAR 13 0 P49736;H0Y8E6 P49736 MCM2 DNA replication licensing factor MCM2 0 0 138.25 0.0057581 4896900 2034.5 2002 2138.8 1983.5 1858.7 2646.9 1848.5 1719 1906.4 2146.3 FALSE FALSE TRUE 1873.467178 2175.043959 2218.065809 1975.292803 1836.536216 2097.903103 1900.363935 2243.115187 1697.27269 2220.883765 0.843568316 0.979359656 0.998731156 0.889417462 0.826939368 0.94462535 0.855679151 1.010010169 0.764233012 1 11.11691817 DTVIIVS(ph)EPS(ph)EDEESQGLPTMAR ddPTM_HeLa_Curcumin_4h_R1 4 DTVIIVSEPSEDEESQGLPTMAR 23 0 Q9H4L7-2;Q9H4L7;D6RAY8 Q9H4L7-2 SMARCAD1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 2 0 DT(0.001)VIIVS(0.813)EPS(0.615)EDEES(0.503)QGLPT(0.067)MAR;DT(0.001)VIIVS(0.988)EPS(0.989)EDEES(0.022)QGLPTMAR;DT(0.002)VIIVS(0.999)EPS(0.981)EDEES(0.018)QGLPTMAR;DT(0.004)VIIVS(0.996)EPS(0.999)EDEES(0.001)QGLPTMAR ;;; 109.41 3.39E-05 24638100 12750.4 9981.3 11489.9 12290.3 13140.7 13101.3 9966 8331.5 10860.6 9982.9 TRUE FALSE FALSE 11741.19239 10844.0391 11915.7258 12239.446 12984.00573 10383.9427 10245.61914 10871.736 9669.219352 10329.80503 1.136632526 1.049781585 1.153528626 1.184867087 1.256945866 1.005240918 0.991850195 1.052462845 0.936050518 1 13.3345254 -2.066374614 15.15225742 1.081025486 0.460155024 0 0.096514411 0 0 0.012599138 0 0.008582729 2.066374614 -0.620870462 DTVLEPYADPYYDYEIER ddPTM_HeLa_Curcumin_4h_R1 2 DTVLEPYADPYYDYEIER 18 0 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 0 0 ; ; 104.7 0.0089277 7708000 2633.93 2328.34 2018.14 2653.21 2308.6 1820.64 1914.64 1806.2 2291.52 2173.72 FALSE FALSE TRUE 2425.451661 2529.591335 2092.934044 2642.23172 2281.071453 1443.018741 1968.359645 2356.902065 2040.145989 2249.256608 1.078334794 1.124634391 0.930500342 1.17471333 1.014144604 0.64155363 0.875115644 1.047858238 0.907031231 1 11.13523255 -5.494960307 24.89058876 1.046871269 0.852032998 0.317963932 0.119103691 507.0894445 452093.4996 0.015082648 0.03364864 3.20E-06 5.494960307 -0.194838271 DTYS(ph)DRSGS(ph)SSPDSEIT(ph)ELKFPSINHD ddPTM_HeLa_Curcumin_4h_R1 1 DTYSDRSGSSSPDSEITELKFPSINHD 27 2 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 3 0 DT(0.022)Y(0.089)S(0.516)DRS(0.273)GS(0.304)S(0.193)S(0.266)PDS(0.454)EIT(0.852)ELKFPS(0.032)INHD 57.02 0.010888 5043700 522.82 471.82 319.61 446.03 854.67 1119 663.88 466.1 931.55 599.59 TRUE FALSE FALSE 481.4382453 512.6020184 331.4550278 444.184446 844.4786185 886.9067863 682.5066861 608.2117443 829.3612956 620.4257079 0.775980491 0.826210152 0.534238062 0.715934947 1.361127703 1.429513276 1.100061905 0.980313576 1.336761654 1 9.277114657 -5.762139482 24.99999848 0.84494263 1.224473199 0.362993922 0.228040332 12.53137023 447511.1504 0.028348935 0.053687224 1.73E-06 5.762139482 0.379530569 VLY(ph)S(ph)QKAT(ph)PGS(ph)SRK ddPTM_HeLa_Curcumin_4h_R1 1 VLYSQKATPGSSRK 14 2 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 4 0 VLY(0.992)S(0.998)QKAT(1)PGS(0.505)S(0.505)RK 49.298 0.019704 4613000 1643.4 1374 1626.2 1622.8 1810.8 1684 1857.5 2316.8 1708.5 1302.4 TRUE FALSE FALSE 1513.323156 1492.762438 1686.468403 1616.085284 1789.207393 1334.719417 1909.616451 3023.181655 1521.081824 1347.658303 1.122927935 1.10767131 1.251406531 1.199180297 1.327641724 0.990398986 1.416988599 2.243284999 1.128685084 1 10.39623903 -4.295932444 2.461463377 1.102048434 2.45198785 0.905757389 0.106159062 0.107186235 0.840662187 0.016743075 0.293393712 5.06E-05 4.295932444 1.349939415 up RGT(ph)SLMEDDEEPIVEDVMMSSEGR ddPTM_HeLa_Curcumin_4h_R1 4 RGTSLMEDDEEPIVEDVMMSSEGR 24 1 Q8N3U4;Q8N3U4-2 Q8N3U4 STAG2 Cohesin subunit SA-2 1 0 RGT(0.5)S(0.5)LMEDDEEPIVEDVMMSSEGR;RGT(0.5)S(0.5)LMEDDEEPIVEDVMMSSEGR;RGT(0.5)S(0.5)LMEDDEEPIVEDVMMSSEGR;RGT(0.5)S(0.5)LMEDDEEPIVEDVMMSSEGR ;;; 117.22 3.91E-07 9411900 1365.59 993.95 1233.16 1187.64 812.643 1516.05 1744.92 2512.79 1407.8 1307.24 TRUE FALSE FALSE 1257.502111 1079.862609 1278.861994 1182.72586 802.952763 1201.604141 1793.877759 3278.928104 1253.367862 1352.666493 0.929646825 0.798321401 0.945437771 0.874366199 0.593607343 0.888322544 1.326178898 2.424047702 0.926590456 1 10.40159046 -4.292286161 2.37885963 0.915648663 2.720231085 0.942882501 0.115406198 0.095552395 0.678602923 0.018419289 0.343522954 5.10E-05 4.292286161 1.804582422 up DTYSDRS(ph)GSS(ph)SPDSEITELKFPSINHD ddPTM_HeLa_Curcumin_4h_R1 1 DTYSDRSGSSSPDSEITELKFPSINHD 27 2 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 2 0 DT(0.048)Y(0.134)S(0.156)DRS(0.546)GS(0.193)S(0.411)S(0.411)PDS(0.099)EIT(0.001)ELKFPSINHD 77.543 7.64E-05 43855000 2183.7 1538.9 1284.2 1672.3 2518.2 3638.1 2235 2155.7 2675.4 1911.6 TRUE FALSE FALSE 2010.857841 1671.915659 1331.793582 1665.380466 2488.17211 2883.51705 2297.708085 2812.963006 2381.915314 1978.027958 1.01659728 0.845243694 0.673293609 0.841939801 1.257905431 1.457773657 1.161615576 1.422104776 1.204186879 1 10.9498471 -5.651781638 5.601364922 0.956678166 1.332250971 0.622332038 0.150588459 0.107999198 4.938983677 0.020889924 0.042183304 2.23E-06 5.651781638 0.375572805 DTYSDRS(ph)GSSS(ph)PDSEITELK ddPTM_HeLa_Curcumin_4h_R1 1 DTYSDRSGSSSPDSEITELK 20 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 2 0 DT(0.064)Y(0.082)S(0.084)DRS(0.538)GS(0.239)S(0.12)S(0.859)PDS(0.01)EIT(0.005)ELK 64.013 0.0081685 22258000 1432.4 1006.1 1418.2 1363 1781.7 1978.4 1593.9 1553.6 1243.7 1208 TRUE FALSE FALSE 1319.024029 1093.062801 1470.75974 1357.360267 1760.454391 1568.057539 1638.620544 2027.285488 1107.269222 1249.97791 1.055237871 0.874465694 1.176628585 1.085907404 1.408388402 1.2544682 1.310919602 1.621857052 0.885831032 1 10.28768688 -2.717776522 0.338000024 0.999022386 3.085183018 0.767999002 0.108262809 5.761479969 0.20636128 0.031472136 6.133109433 0.001915241 2.717776522 2.086160633 DTYSDRSGS(ph)SS(ph)PDSEITELKFPSINHD ddPTM_HeLa_Curcumin_4h_R1 1 DTYSDRSGSSSPDSEITELKFPSINHD 27 2 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 2 0 DT(0.024)Y(0.014)S(0.066)DRS(0.228)GS(0.473)S(0.412)S(0.646)PDS(0.073)EIT(0.057)ELKFPS(0.006)INHD 54.261 0.0026048 10658000 1161 1023.5 859.23 837.04 1488.3 2746.8 1530.5 1464.8 1936.6 1084.3 TRUE FALSE FALSE 1069.105625 1111.966779 891.0738197 833.5765503 1470.552995 2177.082717 1573.441711 1911.410777 1724.159825 1121.979344 0.952874605 0.991075981 0.794198061 0.742951779 1.310677422 1.94039465 1.402380283 1.70360603 1.536712627 1 10.1318304 -5.530113965 5.403467966 0.949749058 1.653180416 0.616259863 0.237719163 0.04689466 4.408942032 0.020575921 0.043446025 2.95E-06 5.530113965 0.703431357 DVAEVDTVRR ddPTM_HeLa_Curcumin_4h_R1 2 DVAEVDTVRR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 167.93 0.00076928 57601000 9486.8 7692.8 8624.2 8578.8 9071.9 10110.6 8237.5 7229.1 10718.5 8648.9 FALSE FALSE TRUE 8735.90977 8357.731354 8943.820439 8543.303199 8963.723518 8013.54759 8468.62208 9433.219311 9542.707366 8949.448631 0.976139439 0.933882264 0.999371113 0.954617826 1.001595058 0.895423609 0.946273053 1.05405592 1.066289976 1 13.12758309 -8.477735062 0.82805784 0.997940883 0.967169716 0.14656116 0.046349557 1.064442304 1.512664047 0.016217189 0.008495861 3.33E-09 8.477735062 -0.030771166 DVDASPS(ph)PLSVQDLK ddPTM_HeLa_Curcumin_4h_R1 1 DVDASPSPLSVQDLK 15 0 Q8IWZ8 Q8IWZ8 SUGP1 SURP and G-patch domain-containing protein 1 1 0 DVDAS(0.054)PS(0.946)PLSVQDLK 229.92 7.15E-21 10754000 3998.8 3428.3 3682.8 3822.5 3704.1 4552.4 3631.4 4102.8 3935.9 3038.9 TRUE FALSE FALSE 3682.29076 3724.626976 3819.287808 3806.683508 3659.931027 3608.180924 3733.287311 5353.724833 3504.141617 3144.501549 1.171025265 1.184488835 1.21459244 1.210584078 1.163914525 1.147457194 1.187242955 1.702567084 1.11437109 1 11.61861563 DVDDFFEHER ddPTM_HeLa_Curcumin_4h_R1 4 DVDDFFEHER 10 0 G3V5X9;Q9UNH7;A0A0A0MRI2;Q9UNH7-2 G3V5X9 SNX6 "Sorting nexin-6;Sorting nexin-6, N-terminally processed" 0 0 ;;; ;;; 190.57 4.50E-05 201969300 32462.1 25960.1 31305.6 28093.2 33523 34589.6 28828.9 27113.8 27553.4 26205.5 FALSE FALSE TRUE 29892.69053 28203.97537 32465.81308 27976.95778 33123.26012 27415.32705 29637.76134 35380.6728 24530.86096 27116.13917 1.102394789 1.040117665 1.197287448 1.031745618 1.221533047 1.011033572 1.092993407 1.30478283 0.904659059 1 14.72686416 -11.2287945 0.020892927 3.21E-09 1.987311013 0.389141808 0.089000089 1370.84677 3.674233914 209.8027385 144.8649862 5.90E-12 11.2287945 1.98731101 DVDDGS(ph)GS(ph)PHS(ph)PHQLSSK ddPTM_HeLa_Curcumin_4h_R1 2 DVDDGSGSPHSPHQLSSK 18 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 3 0 DVDDGS(0.999)GS(0.998)PHS(0.999)PHQLS(0.002)S(0.001)K;DVDDGS(0.997)GS(0.992)PHS(0.996)PHQLS(0.011)S(0.004)K ; 63.522 0.0079878 34440000 9184.5 8438.4 9724.4 8269.6 9471.2 12514.6 8999.5 7467.1 11924.3 10095.1 TRUE FALSE FALSE 8457.537134 9167.777695 10084.79482 8235.382586 9358.262126 9918.930891 9252.001749 9743.784416 10616.23412 10445.90397 0.809651051 0.877643306 0.96543055 0.788383907 0.895878629 0.94955218 0.885706184 0.93278518 1.016305927 1 13.35064973 -9.576556687 1.373607505 0.999687651 0.878668885 0.427730325 0.054134134 0.355791398 1.208554863 0.03937814 0.009308927 2.65E-10 9.576556687 -0.121018766 DVDDGSGS(ph)PHS(ph)PHQLSSK ddPTM_HeLa_Curcumin_4h_R1 1 DVDDGSGSPHSPHQLSSK 18 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 2 0 DVDDGS(0.058)GS(0.941)PHS(0.997)PHQLS(0.003)S(0.002)K 66.308 0.0076021 7060600 12657 10614 10228 9841.9 13696 16815 11171 12003 15654 11029 TRUE FALSE FALSE 11655.18509 11531.42686 10607.05868 9801.176826 13532.68415 13327.37946 11484.42819 15662.65944 13936.79536 11412.25693 1.021286601 1.010442276 0.929444434 0.858828967 1.185802618 1.167812777 1.006324013 1.372441888 1.221212899 1 13.47829651 -1.000000001 0.701711609 1.00289047 43.02759936 0.381753478 0.115559032 157.1223987 0.773002785 0.015031918 10377.56557 0.1 1.000000001 42.02470889 DVDDGSGSPHS(ph)PHQLSSK ddPTM_HeLa_Curcumin_4h_R1 2 DVDDGSGSPHSPHQLSSK 18 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 0 DVDDGSGS(0.099)PHS(0.901)PHQLSSK;DVDDGS(0.002)GS(0.053)PHS(0.939)PHQLS(0.006)SK ; 98.552 0.00060114 39916000 6034.2 5561 4672.2 4074.4 8466 13113.9 7413.1 7677.3 9035.9 5868.8 TRUE FALSE FALSE 5556.586703 6041.668061 4845.355842 4057.541212 8365.048479 10393.92932 7621.091635 10018.07343 8044.684377 6072.740363 0.91500482 0.994883315 0.797886218 0.668156544 1.377475074 1.711571497 1.254967474 1.649679194 1.32472062 1 12.56813197 -5.613367305 6.115459058 0.93098233 1.515662102 0.661388024 0.194088794 0.068794848 3.793437468 0.020940998 0.042251494 2.44E-06 5.613367305 0.584679772 DVDELPSLQPSVGS(ph)PSRPSSSR ddPTM_HeLa_Curcumin_4h_R1 4 DVDELPSLQPSVGSPSRPSSSR 22 1 O43815-2;O43815 O43815-2 STRN Striatin 1 0 DVDELPSLQPS(0.002)VGS(0.497)PS(0.497)RPS(0.001)S(0.001)S(0.002)R;DVDELPSLQPS(0.297)VGS(0.51)PS(0.192)RPS(0.001)S(0.001)SR;DVDELPSLQPS(0.023)VGS(0.704)PS(0.258)RPS(0.006)S(0.006)S(0.004)R;DVDELPSLQPS(0.03)VGS(0.722)PS(0.245)RPS(0.001)S(0.001)S(0.001)R ;;; 157.57 1.04E-06 116237000 12659.8 10063.5 10567.2 11132.7 11044.1 16175.7 14047.3 7512.9 12151.5 10013.7 TRUE FALSE FALSE 11657.76347 10933.3441 10958.82973 11086.63584 10912.40632 12820.67748 14441.42943 9803.548625 10818.51085 10361.67533 1.125084805 1.055171461 1.057631066 1.069965569 1.053150767 1.237317043 1.393734987 0.946135476 1.044088963 1 13.33896966 -13.52287864 0.033586233 0.262436601 1.60919824 0.121112362 0.114602569 1198.62866 3.226415562 103.1917061 40.06429119 3.00E-14 13.52287864 1.346761639 DVDETGITVAS(ph)LER ddPTM_HeLa_Curcumin_4h_R1 2 DVDETGITVASLER 14 0 Q8WU90;H7C466 Q8WU90 ZC3H15 Zinc finger CCCH domain-containing protein 15 1 0 DVDETGITVAS(1)LER;DVDETGITVAS(1)LER ; 233.28 1.03E-20 46389000 2778.8 2296.7 2336.2 3024.9 2743.1 3363.5 3058 2275.1 2653.1 2513.3 TRUE FALSE FALSE 2558.855048 2495.216514 2422.781627 3012.383765 2710.390324 2665.872186 3143.79925 2968.767517 2362.061568 2600.636988 0.983933959 0.959463595 0.931610847 1.158325356 1.042202482 1.025084315 1.208857393 1.141553985 0.908262698 1 11.34464932 -6.259651882 24.99275434 0.985079504 1.111345267 0.630020886 0.058728035 90.85647015 1270347.601 0.008320971 0.013342247 5.50E-07 6.259651882 0.126265763 DVDFEGTDEPIFGK ddPTM_HeLa_Curcumin_4h_R1 1 DVDFEGTDEPIFGK 14 0 P42285;H0Y8U3 P42285 SKIV2L2 Superkiller viralicidic activity 2-like 2 0 0 131.83 0.0087948 4105500 2733.4 2132.7 2332.3 2411.2 2441.9 2770.7 2035 2292.1 2566.7 2401.7 FALSE FALSE TRUE 2517.048506 2317.041085 2418.73709 2401.223093 2412.781937 2196.025588 2092.096623 2990.950738 2285.139432 2485.158896 1.01283202 0.932351283 0.973272612 0.966225177 0.970876325 0.883656007 0.84183616 1.203524951 0.919514416 1 11.27912238 -7.279171807 23.27057407 1.006059568 0.959657454 0 0.093702764 757.3323703 993857.4259 0.014132072 0.016183343 5.26E-08 7.279171807 -0.046402114 DVDIIDHHDNTYTVK ddPTM_HeLa_Curcumin_4h_R1 2 DVDIIDHHDNTYTVK 15 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 78.985 0.0048521 211575000 9567 7591.5 9542 9805.2 9002.2 10472.2 9295 7157.3 10057.4 8579.7 FALSE FALSE TRUE 8809.761855 8247.675433 9895.634914 9764.62868 8894.854645 8300.147674 9555.792684 9339.527822 8954.128382 8877.843936 0.992331237 0.929017844 1.114643937 1.0998874 1.001916086 0.934928315 1.076364121 1.052004055 1.008592677 1 13.11599363 -6.767608566 24.99999242 0.991225402 1.04328762 0.25909285 0.052123188 194.7344778 789141.4792 0.008622285 0.011488142 1.71E-07 6.767608566 0.052062218 DVDLEFLAK ddPTM_HeLa_Curcumin_4h_R1 2 DVDLEFLAK 9 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 ; ; 153.08 0.0010303 24355090 3839.95 2801.73 3447.77 3299 3149.25 4009.54 3182.64 3186.24 3803.52 2904.53 FALSE FALSE TRUE 3536.013906 3043.899057 3575.547389 3285.349612 3111.697251 3177.916207 3271.936313 4157.709908 3386.283372 3005.462201 1.176529156 1.012789 1.189683034 1.093126246 1.035347325 1.057380195 1.088663272 1.383384528 1.126709686 1 11.55337116 -9.486069284 1.151972873 0.997980914 1.125602531 0.001712339 0.107620784 0.697316149 1.612716736 0.072969137 0.016685488 3.27E-10 9.486069284 0.127621617 DVDVSEDS(ph)PPPLPER ddPTM_HeLa_Curcumin_4h_R1 2 DVDVSEDSPPPLPER 15 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 0 DVDVS(0.337)EDS(0.663)PPPLPER;DVDVS(0.006)EDS(0.994)PPPLPER ; 158.65 0.00033224 98232000 4399.7 4128.7 4469.5 4435.6 5788.9 4955.4 4858 4207.6 3863.3 3815.8 TRUE FALSE FALSE 4051.459102 4485.566431 4635.143602 4417.246662 5719.871148 3927.594181 4994.302405 5490.477871 3439.505656 3948.398766 1.026101805 1.136046964 1.173929959 1.118743806 1.448655895 0.994730881 1.264893113 1.390558096 0.871114054 1 11.94705199 -6.779051683 0.783955404 1.002942331 1.258502955 0.48273047 0.124816152 0.384760555 0.476472347 0.024457853 0.039730082 1.66E-07 6.779051683 0.255560624 DVEDEETWIR ddPTM_HeLa_Curcumin_4h_R1 2 DVEDEETWIR 10 0 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 ; ; 239.6 3.30E-22 201260000 7027.5 5737 5891.9 6615 5352.2 7348.4 6036.7 6303 7344.1 6011.1 FALSE FALSE TRUE 6471.26596 6232.880716 6110.258997 6587.628883 5288.378511 5824.259006 6206.073555 8224.755685 6538.470604 6219.985278 1.040398919 1.002073227 0.982359077 1.059106829 0.850223638 0.936378262 0.997763383 1.322311118 1.05120355 1 12.60269545 -4.261116677 24.43256221 1.00068391 1.322311244 0.738561307 0.058875284 7.660661446 579636.8191 0.008251278 0.06473416 5.48E-05 4.261116677 0.321627334 DVEDEILWVGER ddPTM_HeLa_Curcumin_4h_R1 4 DVEDEILWVGER 12 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 ;;; ;;; 254.24 1.38E-34 70577900 7456.9 5887.52 6304.18 6875 7281.8 8356.4 7320.1 6576.8 6933.1 6114.02 FALSE FALSE TRUE 6866.678497 6396.410995 6537.818457 6846.553072 7194.969291 6623.188444 7525.482305 8582.036044 6172.556276 6326.48174 1.085386599 1.011053419 1.033405094 1.082205458 1.137278125 1.046899164 1.189520908 1.356525854 0.975669658 1 12.6271877 -1.000000004 0.630376404 1.039815143 25.90186118 0.844515214 0.042412332 51.31081411 0.329474975 0.00741593 1776.198332 0.099999999 1.000000004 24.86204604 DVEDEILWVTER ddPTM_HeLa_Curcumin_4h_R1 3 DVEDEILWVTER 12 0 O15020;O15020-2 O15020 SPTBN2 "Spectrin beta chain, non-erythrocytic 2" 0 0 ;; ;; 183.85 0.0004981 4549440 2988.9 2399.48 2703.75 2721.11 2641.01 3619.98 2233.54 1979.93 3333.16 2504.68 FALSE FALSE TRUE 2752.325411 2606.880359 2803.953353 2709.850768 2609.517681 2869.155342 2296.207121 2583.601543 2967.520687 2591.717444 1.061969706 1.005850528 1.081890065 1.045581097 1.006868124 1.107047896 0.885978958 0.996868524 1.145001626 1 11.33969272 -4.755507559 24.99999969 1.035667101 0.941423757 0.378419462 0.053958093 92.83224884 391234.57 0.005601788 0.019914633 1.76E-05 4.755507559 -0.094243344 DVEDESTGLEK ddPTM_HeLa_Curcumin_4h_R1 4 DVEDESTGLEK 11 0 P36952 P36952 SERPINB5 Serpin B5 0 0 ;;; ;;; 228.64 3.52E-40 12814700 8747.7 7805.3 7839.6 7762.8 7963.7 9939.5 7292.3 7287.9 8220.7 7873 FALSE FALSE TRUE 8055.310314 8479.955352 8130.142472 7730.67959 7868.738079 7877.935659 7496.902312 9509.947161 7318.909777 8146.586164 0.988795816 1.040921336 0.997981524 0.948947134 0.965893924 0.967022935 0.920250785 1.167353658 0.898402058 1 12.99197991 -4.24770415 24.77674762 0.987369075 1.167353794 0.64358475 0.042324268 819.7599524 1478723.705 0.004475052 0.118879245 5.65E-05 4.24770415 0.179984719 DVEDMELS(ph)DVEDDGSK ddPTM_HeLa_Curcumin_4h_R1 4 DVEDMELSDVEDDGSK 16 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 DVEDMELS(1)DVEDDGSK;DVEDMELS(1)DVEDDGSK;DVEDMELS(1)DVEDDGSK;DVEDMELS(1)DVEDDGSK ;;; 298.1 8.86E-81 58098200 13020 12268.36 13155.6 11933.8 17795.5 13024.8 12453.5 9994.54 9842.4 9567.1 TRUE FALSE FALSE 11989.45326 13328.78237 13643.15811 11884.4211 17583.30029 10323.30966 12802.91169 13041.82924 8762.713344 9899.556013 1.2111102 1.346402036 1.378158585 1.200500415 1.776170594 1.042805318 1.293281403 1.317415571 0.885162257 1 13.27314811 -8.158853082 0.708300616 1.020685226 1.340259549 0.402057442 0.18155332 0.488088874 0.537664091 0.067759541 0.041905487 6.94E-09 8.158853082 0.319574323 DVEDMELS(ph)DVEDDGSKIIVEDR ddPTM_HeLa_Curcumin_4h_R1 2 DVEDMELSDVEDDGSKIIVEDR 22 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 DVEDMELS(1)DVEDDGSKIIVEDR;DVEDMELS(1)DVEDDGSKIIVEDR ; 136.61 1.13E-05 13090900 4353.9 4244.9 4766.3 4026.6 4839.3 5729.7 4170.6 3543.8 4530.1 4135 TRUE FALSE FALSE 4009.284221 4611.810241 4942.943271 4009.938996 4781.594508 4541.295633 4287.615811 4624.288306 4033.159364 4278.690942 0.937035246 1.077855424 1.155246625 0.937188278 1.117536782 1.061375008 1.002085888 1.080771752 0.942615257 1 12.06295376 -7.255297258 24.96873973 0.970266644 1.060369688 0.384567217 0.058580182 397.4292015 1615616.148 0.009534205 0.011521511 5.56E-08 7.255297258 0.090103045 DVEGST(ph)SPQIGDKVEFSISDK ddPTM_HeLa_Curcumin_4h_R1 1 DVEGSTSPQIGDKVEFSISDK 21 1 O75534-2;O75534;O75534-3;O75534-4;E9PLT0 O75534-2 CSDE1 Cold shock domain-containing protein E1 1 0 DVEGS(0.105)T(0.448)S(0.448)PQIGDKVEFSISDK 90.912 0.00036795 8071500 776.05 681.09 729.26 708.65 565.16 1143 703.9 1543.6 734.6 702.4 TRUE FALSE FALSE 714.6248236 739.9603847 756.2870171 705.7177941 558.4208361 905.9289157 723.6495396 2014.236534 654.0162179 726.8083477 0.983236951 1.018095605 1.040559068 0.97098196 0.768319238 1.246448144 0.995653864 2.771344799 0.899846872 1 9.505431179 -4.261398964 24.97378995 0.997714029 2.771345323 0.957270161 0.112806639 0.384791661 236925.8355 0.013651363 0.105177602 5.48E-05 4.261398964 1.773631294 DVEGSTS(ph)PQIGDKVEFSISDK ddPTM_HeLa_Curcumin_4h_R1 1 DVEGSTSPQIGDKVEFSISDK 21 1 O75534-2;O75534;O75534-3;O75534-4;E9PLT0 O75534-2 CSDE1 Cold shock domain-containing protein E1 1 0 DVEGS(0.065)T(0.384)S(0.551)PQIGDKVEFSISDK 93.583 0.00016035 7329700 1314.2 1097.1 1022.8 1395.8 1200 1435.8 1245.9 2583.5 1713.5 1315.3 TRUE FALSE FALSE 1210.179683 1191.928435 1060.705868 1390.024549 1185.690784 1137.998895 1280.856601 3371.197257 1525.533337 1361.006577 0.889179893 0.875769784 0.779353962 1.021320964 0.871186667 0.836145037 0.94110978 2.476988219 1.120886087 1 10.41045832 -4.261537046 7.428916941 0.9221239 2.494713415 0.96050584 0.09434919 0.011007231 5.632280963 0.010770611 0.086482549 5.48E-05 4.261537046 1.572589515 DVEPEDPMFLMDPFAIHR ddPTM_HeLa_Curcumin_4h_R1 1 DVEPEDPMFLMDPFAIHR 18 0 Q15773;F5H7L5;F5H800;F5H0Y3 Q15773 MLF2 Myeloid leukemia factor 2 0 0 55.094 0.013303 2394500 991.63 996.45 1042.3 827.01 935.72 1598.3 1036.8 762.76 1177.3 1244.7 FALSE FALSE TRUE 913.1414391 1082.578698 1080.928555 823.5880517 924.5621501 1266.794563 1065.889818 995.3220127 1048.153135 1287.953232 0.708986488 0.840541932 0.839260718 0.639454936 0.717853822 0.983571866 0.827584256 0.772793598 0.81381304 1 10.33086449 -9.447290184 1.132440254 1.002176648 0.786528178 0.062023325 0.104898072 0.394381056 0.889907608 0.067998477 0.016235554 3.57E-10 9.447290184 -0.21564847 DVERDVFLYR ddPTM_HeLa_Curcumin_4h_R1 2 DVERDVFLYR 10 1 M0QXB4;O14579-3;O14579;M0R061;O14579-2 M0QXB4 COPE Coatomer subunit epsilon 0 0 ; ; 91.265 0.0095502 5406200 5083.7 3209.3 2523.36 3843.7 2400.04 4373.3 3174.5 3473.3 6131 4862.7 FALSE FALSE TRUE 4681.319781 3486.697592 2616.877941 3827.795788 2371.421091 3466.228283 3263.567926 4532.293181 5458.444639 5031.678463 0.930369421 0.692949205 0.520080518 0.760739347 0.471298217 0.688881118 0.648604228 0.90075175 1.084815868 1 12.29682402 -7.276321833 3.476908749 0.970148077 0.656650229 0.628710979 0.117815414 0.109045003 2.757906583 0.018556141 0.021816062 5.29E-08 7.276321833 -0.313497848 DVES(ph)PSWR ddPTM_HeLa_Curcumin_4h_R1 1 DVESPSWR 8 0 F5H6E2;O00159-2;O00159-3;O00159 F5H6E2 MYO1C Unconventional myosin-Ic 1 0 DVES(0.993)PS(0.007)WR 144.77 0.0025197 116800000 3217.9 2543 2486.9 2493.2 2695.1 2566.7 2604.4 3240.4 2768.4 2338.9 TRUE FALSE FALSE 2963.199819 2762.805589 2579.066702 2482.883799 2662.962693 2034.337487 2677.472455 4228.383043 2464.713446 2420.176601 1.224373386 1.141571895 1.065652275 1.025910175 1.100317511 0.840573984 1.106312842 1.747138222 1.018402312 1 11.24089661 -4.263278709 6.332297155 1.083703339 1.761327879 0.812216377 0.098754986 0.044786165 10.06379167 0.015912257 0.130485407 5.45E-05 4.263278709 0.67762454 DVESPS(ph)WR ddPTM_HeLa_Curcumin_4h_R1 1 DVESPSWR 8 0 F5H6E2;O00159-2;O00159-3;O00159 F5H6E2 MYO1C Unconventional myosin-Ic 1 0 DVES(0.001)PS(0.999)WR 93.178 0.019046 4867200 3046.1 2820.2 2328.3 2862.4 2455 3455.7 2306 3536.3 2736.9 2622.3 TRUE FALSE FALSE 2804.997971 3063.965521 2414.588846 2850.556147 2425.725728 2738.948866 2370.700154 4614.501591 2436.668917 2713.42473 1.033748215 1.129187586 0.889867635 1.050538132 0.893971998 1.009406613 0.873692986 1.700618978 0.898004979 1 11.40589917 -4.254971566 24.94907111 1.002007243 1.7006193 0.8678276 0.084335235 161.6200881 623419.2135 0.009884004 0.125953876 5.56E-05 4.254971566 0.698612057 DVESYIHR ddPTM_HeLa_Curcumin_4h_R1 1 DVESYIHR 8 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 0 0 127.02 0.0048547 2786600 2377.5 2375.4 2971.2 2416.2 3631.7 4267.1 2966.9 2073.2 3066.5 2420.4 FALSE FALSE TRUE 2189.318366 2580.718991 3081.315286 2406.202405 3588.394349 3382.05536 3050.143229 2705.309136 2730.112622 2504.50872 0.874150826 1.03042923 1.23030727 0.960748264 1.43277375 1.350386738 1.217860894 1.080175571 1.090079104 1 11.29031192 -6.639788157 1.318075828 0.940311557 1.243122114 0.347194579 0.135898758 0.250401051 0.87545385 0.023138761 0.036675262 2.29E-07 6.639788157 0.302810558 DVFFYQADDEHYIPR ddPTM_HeLa_Curcumin_4h_R1 3 DVFFYQADDEHYIPR 15 0 K7EKE5;K7EIS0;Q9NRH3;P23258 K7EKE5 TUBG1;TUBG2 Tubulin gamma chain;Tubulin gamma-2 chain;Tubulin gamma-1 chain 0 0 ;; ;; 150.12 0.00035346 30886800 11831.4 10484.8 10835.8 10671.2 10808.7 15655.6 11487.3 11076.3 11874.6 10696.6 FALSE FALSE TRUE 10894.93221 11391.05939 11237.38428 10627.0454 10679.81331 12408.45209 11809.60272 14453.41288 10571.98609 11068.30605 0.984336009 1.029160139 1.01527589 0.960132955 0.964900434 1.121079597 1.066974717 1.305837841 0.955158453 1 13.43414682 -1.000000012 0.778839142 0.993486589 68.12322973 0.850725794 0.039137835 101.3740165 0.364326975 0.005604954 11990.17365 0.099999997 1.000000012 67.12974314 DVGRPNFEEGGPTS(ph)VGR ddPTM_HeLa_Curcumin_4h_R1 1 DVGRPNFEEGGPTSVGR 17 1 Q6Y7W6-4;Q6Y7W6-5;Q6Y7W6;E7ESB6 Q6Y7W6-4 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 0 DVGRPNFEEGGPT(0.248)S(0.752)VGR 119.37 0.00033268 0 373.27 342.59 298.84 375.74 405.65 528.16 556.74 199.98 421.04 319.89 TRUE FALSE FALSE 343.7252856 372.201953 309.9152733 374.1852874 400.8128887 418.6136624 572.360626 260.9529814 374.8529654 331.0061537 1.038425666 1.124456295 0.936282513 1.13044813 1.21089256 1.264670332 1.729154034 0.788362931 1.132465246 1 8.370714228 -5.771154284 2.064572868 1.022799893 1.300088684 0.145261637 0.219352378 0.313087374 2.719420491 0.02945678 0.064381644 1.69E-06 5.771154284 0.27728879 DVGRPQPGR ddPTM_HeLa_Curcumin_4h_R1 2 DVGRPQPGR 9 1 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 0 ; ; 110.76 0.0016158 11873400 3393.1 3345.3 4142.1 4202.9 4672.8 5229.5 4231.8 3856.6 3182.3 3038.2 FALSE FALSE TRUE 3124.532555 3634.452826 4295.60987 4185.509513 4617.079912 4144.842751 4350.532919 5032.459586 2833.209652 3143.777224 0.993878488 1.156078363 1.366384945 1.331363266 1.468640932 1.318427629 1.383855346 1.600768511 0.901211966 1 11.61828327 -6.878889889 1.74033603 0.994518651 1.417361381 0.865725217 0.079621711 0.078956851 0.482658259 0.012301607 0.016984177 1.32E-07 6.878889889 0.42284273 DVGSLDEK ddPTM_HeLa_Curcumin_4h_R1 1 DVGSLDEK 8 0 Q99584 Q99584 S100A13 Protein S100-A13 0 0 96.948 0.016209 2608400 3091.4 2682.3 2709.5 2730.9 2610.8 3438.6 2684.5 2527.7 3129.7 2902.5 FALSE FALSE TRUE 2846.712428 2914.14606 2809.916454 2719.600259 2579.667915 2725.395599 2759.819845 3298.384094 2786.37974 3003.361659 0.947842035 0.970294753 0.935590439 0.905518738 0.858926832 0.907448356 0.918910261 1.098230739 0.92775365 1 11.5523625 -8.598898791 0.604586003 1.000089355 0.934442732 0 0.063325183 1.263287701 0.919170742 0.040357239 0.015146093 2.52E-09 8.598898791 -0.065646624 DVHTLLDR ddPTM_HeLa_Curcumin_4h_R1 1 DVHTLLDR 8 0 E9PI41;Q9NPD3 E9PI41 EXOSC4 Exosome complex component RRP41 0 0 145.16 0.0019771 7959600 5100.8 4317.9 4201 4328.5 4606.7 5160.9 4585.5 4249.8 4852.9 4637.8 FALSE FALSE TRUE 4697.066298 4691.120036 4356.692756 4310.589814 4551.768111 4090.471165 4714.156789 5545.544456 4320.549011 4798.963205 0.978766891 0.977527819 0.907840417 0.898233562 0.948489896 0.852365603 0.98232818 1.155571364 0.900308843 1 12.22850704 -6.98465763 23.86702319 0.989350844 0.950053015 0 0.080898587 350.7634408 545653.9457 0.012179014 0.016002487 1.04E-07 6.98465763 -0.039297829 DVIEEYFK ddPTM_HeLa_Curcumin_4h_R1 2 DVIEEYFK 8 0 P25398 P25398 RPS12 40S ribosomal protein S12 0 0 ; ; 131.06 0.0015597 9017800 8383.2 6403.7 7871.4 7761.1 7043.2 7596.1 6616.5 5625 6470.4 4549 FALSE FALSE TRUE 7719.660874 6957.207294 8163.121008 7728.986625 6959.21444 6020.583234 6802.141183 7340.036606 5760.613308 4707.077411 1.640011455 1.478031204 1.734222809 1.641992674 1.478457614 1.279049123 1.445088021 1.559361779 1.223819539 1 12.20061586 -9.311048252 0.953993543 0.98884773 1.533844199 0.587686572 0.136239147 0.26096104 0.41164872 0.100396586 0.024657466 4.89E-10 9.311048252 0.544996469 DVLDVYIEHR ddPTM_HeLa_Curcumin_4h_R1 2 DVLDVYIEHR 10 0 P33993;P33993-2 P33993 MCM7 DNA replication licensing factor MCM7 0 0 ; ; 154.24 0.00051706 9805700 13011.6 11172.8 13448.8 13053.5 16390.9 14730.2 13755 11339.7 11616.5 11192.3 FALSE FALSE TRUE 11981.71813 12138.52705 13947.22436 12999.48808 16195.44922 11674.99048 14140.92828 14797.12233 10342.19901 11581.23159 1.034580652 1.048120569 1.204295437 1.122461629 1.398422015 1.008095761 1.221021112 1.277681239 0.893013747 1 13.49950106 -6.817244012 2.546825011 1.016164597 1.205028923 0.501343027 0.102478307 0.174778886 2.322836177 0.014632222 0.020261076 1.52E-07 6.817244012 0.188864326 DVLLQVDDERR ddPTM_HeLa_Curcumin_4h_R1 6 DVLLQVDDERR 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ;;;;; ;;;;; 235.49 4.92E-17 145379600 26929.6 24277.3 26629.2 27124 26006.3 27100.1 25002.1 21172.4 26440.5 22982.1 FALSE FALSE TRUE 24798.09374 26375.72163 27616.10158 27011.76807 25696.19186 21479.23378 25703.59164 27627.76729 23540.0433 23780.72626 1.042781178 1.109121788 1.161280832 1.135868088 1.080546976 0.903220261 1.080858143 1.161771385 0.989879074 1 14.53750516 -7.659895778 1.98907712 1.014711453 1.086232766 0.212829365 0.070201938 0.41872268 3.445682005 0.014786838 0.01506727 2.19E-08 7.659895778 0.071521313 DVMEDAVEDRLDR ddPTM_HeLa_Curcumin_4h_R1 2 DVMEDAVEDRLDR 13 1 R4GMY7;M0R1A1;Q15833-2;Q15833;Q15833-3 R4GMY7 STXBP2 Syntaxin-binding protein 2 0 0 ; ; 130.1 0.0014192 6199100 1952.09 1761.45 1848.32 1836.08 1943.86 2198.9 1691.62 1548.32 1647.03 1717.71 FALSE FALSE TRUE 1797.580017 1913.701889 1916.820365 1828.482787 1920.680739 1742.823353 1739.082304 2020.39564 1466.35493 1777.400295 1.011353504 1.07668593 1.078440445 1.028740005 1.080612367 0.98054634 0.978441553 1.136713911 0.824999824 1 10.79555292 -7.42248326 7.144202012 1.004963802 1.04717778 0.195825122 0.072733258 0.355495465 22.08871675 0.007532554 0.008576798 3.78E-08 7.42248326 0.042213979 QIPS(ph)AEDLETDGGGPGQVVDDGLEHR ddPTM_HeLa_Curcumin_4h_R1 3 QIPSAEDLETDGGGPGQVVDDGLEHR 26 0 J3KPH8;Q8WUI4-3;Q8WUI4-4;Q8WUI4;Q8WUI4-7;Q8WUI4-6;Q8WUI4-5;Q8WUI4-8;Q8WUI4-10 J3KPH8 HDAC7 Histone deacetylase;Histone deacetylase 7 1 0 QIPS(0.995)AEDLET(0.005)DGGGPGQVVDDGLEHR;QIPS(1)AEDLETDGGGPGQVVDDGLEHR;QIPS(0.999)AEDLET(0.001)DGGGPGQVVDDGLEHR ;; 189.4 5.77E-36 18304900 1934.16 1574.06 1824.99 1804.87 1690.75 2983.46 3429.99 4584.71 2105.44 2092.77 TRUE FALSE FALSE 1781.069195 1710.114733 1892.625735 1797.401926 1670.588911 2364.656765 3526.226288 5982.566974 1874.4785 2165.493602 0.822477237 0.789711284 0.873992762 0.830019504 0.771458715 1.091971255 1.62837068 2.762680513 0.865612578 1 11.08048019 -4.291712743 1.552185226 0.88563801 3.409506169 0.984901401 0.07264118 0.108952568 0.251969344 0.013955322 0.409590009 5.11E-05 4.291712743 2.523868159 up DVMSDETNNEETESPS(ph)QEFVNITK ddPTM_HeLa_Curcumin_4h_R1 1 DVMSDETNNEETESPSQEFVNITK 24 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 DVMSDETNNEETESPS(1)QEFVNITK 144.4 8.14E-07 5535100 2125.4 1657.8 1652 1971.3 2306.3 2982.4 1246 1150.5 1917 1719.6 TRUE FALSE FALSE 1957.172347 1801.092845 1713.224573 1963.143283 2278.798879 2363.816621 1280.959407 1501.282154 1706.709896 1779.355972 1.099932997 1.012216146 0.962834082 1.10328867 1.280687459 1.328467523 0.719900586 0.84372221 0.959172826 1 10.79713944 -4.734423864 24.99962809 1.075362577 0.781811127 0.502606955 0.122922668 147.4247157 136421.7154 0.017493432 0.065419775 1.84E-05 4.734423864 -0.293551451 DVNAAIAAIK ddPTM_HeLa_Curcumin_4h_R1 2 DVNAAIAAIK 10 0 P68366-2;P68366 P68366-2 TUBA4A Tubulin alpha-4A chain 0 0 ; ; 99.788 0.011196 10061900 6962.9 4854.7 6338.1 5468.6 6110.6 7302.1 5362.1 5845.4 5810.6 6033.6 FALSE FALSE TRUE 6411.779118 5274.318636 6572.995562 5445.972382 6037.735086 5787.562148 5512.546095 7627.635551 5173.191717 6243.267151 1.026990991 0.844801049 1.052813439 0.872295266 0.967079406 0.927008569 0.882958547 1.221737812 0.828603293 1 12.60808549 DVNAAIATIK ddPTM_HeLa_Curcumin_4h_R1 2 DVNAAIATIK 10 0 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;A0A1W2PQM2;P0DPH7-2;Q6PEY2;P68363;P68363-2 Q9BQE3;P68363 TUBA1C;TUBA3E;TUBA1B Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain 0 0 ; ; 173.71 8.89E-13 105341000 16107.5 12682.6 14140.9 13328.9 13788.9 14257.8 13149 11759.6 13560.9 13535.7 FALSE FALSE TRUE 14832.57438 13778.82743 14664.97419 13273.74854 13624.47637 11300.57156 13517.92555 15345.04791 12073.3032 14006.06457 1.059010853 0.983775804 1.047044594 0.947714362 0.972755502 0.806834176 0.965148025 1.095600255 0.862005393 1 13.77376402 -6.252247851 23.52714159 1.025873462 0.950494139 0 0.085587791 356.0108192 911261.8745 0.010345617 0.016979593 5.59E-07 6.252247851 -0.075379324 DVNQQEFVR ddPTM_HeLa_Curcumin_4h_R1 1 DVNQQEFVR 9 0 P39019;M0R2L9;M0QYF7;M0R140 P39019 RPS19 40S ribosomal protein S19 0 0 148.69 0.015239 29810000 1360.5 850.26 1135.3 1154.2 1431.3 1669 1259.7 1175.4 1560 1239.3 FALSE FALSE TRUE 1252.814989 923.7526857 1177.375217 1149.424226 1414.232682 1322.830586 1295.043792 1533.774049 1388.871903 1282.365583 0.976956186 0.720350498 0.918127586 0.896331157 1.102831128 1.031554967 1.009886579 1.196050541 1.083054569 1 10.3245919 -1.000023074 0.706382086 0.961829077 30.77899587 0.337426289 0.100607562 255.8945662 1.236590551 0.016350134 12080.30987 0.099994687 1.000023074 29.8171668 DVNVSELMK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 DVNVSELMKK 10 1 A0A1B0GUE0;Q96N16-5;Q96N16-2 A0A1B0GUE0 0 1 DVNVSELMK(1)K 63.184 0.016946 44435000 1406 1057.9 1002.4 950.26 953.7 1861.3 1583.4 1601.7 1349.2 1129.3 FALSE TRUE FALSE 1294.713616 1149.340162 1039.549826 946.3280759 942.3277504 1475.245399 1627.825942 2090.050957 1201.196136 1168.543091 1.107972506 0.983566777 0.889611888 0.80983584 0.806412496 1.262465552 1.393038866 1.788595537 1.027943381 1 10.19049522 -4.568594512 1.656923057 1.004116595 1.830344602 0.839590691 0.115345369 0.194696118 0.775276654 0.019360983 0.212065921 2.70E-05 4.568594512 0.826228007 DVPNETLQVEEDDRPELPWWK ddPTM_HeLa_Curcumin_4h_R1 2 DVPNETLQVEEDDRPELPWWK 21 1 O95373 O95373 IPO7 Importin-7 0 0 ; ; 113.73 1.70E-05 25215000 4259.9 3646.7 4517.5 3963.1 4309.1 4518.5 3874.4 3175.6 3783.3 3652 FALSE FALSE TRUE 3922.72442 3961.904499 4684.922524 3946.701742 4257.716797 3581.312166 3983.105237 4143.825821 3368.281455 3778.906728 1.038058016 1.048426115 1.239756062 1.044403058 1.126705977 0.947711183 1.054036398 1.096567372 0.891337548 1 11.88375319 -7.457975795 2.128720123 1.014676433 1.079912345 0.226507817 0.079821245 0.438237963 3.864544837 0.013144187 0.014508433 3.48E-08 7.457975795 0.065235912 DVPPDILLDS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 6 DVPPDILLDSPER 13 0 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 1 0 DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER;DVPPDILLDS(1)PER ;;;;; 214.89 1.90E-13 101363900 15219.48 12213.32 12268.6 14116.13 12614.17 17076.62 12135.23 7256.83 14363.68 14183.58 TRUE FALSE FALSE 14014.8421 13268.98496 12723.28511 14057.72119 12463.75426 13534.73652 12475.71189 9469.404061 12788.02024 14676.45835 0.954919897 0.90409993 0.866917945 0.957841521 0.849234465 0.922207265 0.850049215 0.645210434 0.871328759 1 13.84121625 -2.717585883 0.353672874 0.979909816 1.73E-35 0.56607179 0.060947164 6.493495521 0.243426347 0.015201895 3.432576004 0.001916082 2.717585883 -0.979909816 DVPPDILLDS(ph)PERK ddPTM_HeLa_Curcumin_4h_R1 6 DVPPDILLDSPERK 14 1 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 1 0 DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK;DVPPDILLDS(1)PERK ;;;;; 194.67 6.20E-06 231619900 24464.54 22848.3 23629 25471.1 23841.75 29402 21901.62 13359.43 27140.7 25043.39 TRUE FALSE FALSE 22528.14584 24823.20524 24504.71153 25365.70734 23557.4527 23303.69377 22516.12051 17432.65871 24163.43311 25913.64594 0.869354544 0.957920213 0.945629634 0.97885521 0.909075194 0.899282711 0.86889049 0.672721189 0.9324598 1 14.66142439 -3.621095836 1.060836813 0.940588627 5.34E-12 0.845491359 0.034320991 2.308818357 0.784284863 0.007479954 3.408035308 0.000239279 3.621095836 -0.940588627 DVQGTDASLDEELDR ddPTM_HeLa_Curcumin_4h_R1 2 DVQGTDASLDEELDR 15 0 A0A087WYB4;Q9UJZ1-2;Q9UJZ1 A0A087WYB4 STOML2 "Stomatin-like protein 2, mitochondrial" 0 0 ; ; 225.55 9.65E-20 9743900 1860.27 1393.33 1776.85 1658.23 2110.6 2130.5 1829.7 14044.8 1947.38 1270.82 FALSE FALSE TRUE 1713.027667 1513.763237 1842.701624 1651.368684 2085.432473 1688.610284 1881.036458 18326.99487 1733.757286 1314.9809 1.302701557 1.15116747 1.401314364 1.255811916 1.585903242 1.284132936 1.430466752 13.93708065 1.318465755 1 10.36082613 -4.261361339 6.733607394 1.216685701 14.15824134 0.998293507 0.156690851 0.003740535 1.132945474 0.026543433 0.219210922 5.48E-05 4.261361339 12.94155564 DVQGTDASLDEELDRVK ddPTM_HeLa_Curcumin_4h_R1 2 DVQGTDASLDEELDRVK 17 1 A0A087WYB4;Q9UJZ1-2;Q9UJZ1 A0A087WYB4 STOML2 "Stomatin-like protein 2, mitochondrial" 0 0 ; ; 182.28 5.28E-06 10094500 1955.31 1793.63 2154.28 1664.19 2027.57 2963.7 2272.8 2019.89 1989.56 1598.54 FALSE FALSE TRUE 1800.54515 1948.663385 2234.119512 1657.304023 2003.392552 2348.995212 2336.568651 2635.745163 1771.310246 1654.089146 1.088541784 1.17808849 1.350664514 1.001943593 1.211175684 1.420114035 1.412601405 1.593472256 1.070867462 1 10.69182127 -1 0.240975251 1.001561561 4.56104137 0.741520061 0.097711921 15.89800556 0.196342724 0.057217702 22.91744147 0.1 1 3.559479809 DVQIGDIVTVGECRPLSK ddPTM_HeLa_Curcumin_4h_R1 1 DVQIGDIVTVGECRPLSK 18 1 P62280;M0R1H5 P62280 RPS11 40S ribosomal protein S11 0 0 123.4 0.00024913 17646000 450.25 213.07 156.44 244.71 217.47 369.02 450.68 214.35 199.96 495.89 FALSE FALSE TRUE 414.6122374 231.4868214 162.237804 243.6974549 214.8768123 292.4810923 463.3248679 279.7043283 178.0248883 513.1221406 0.808018607 0.451133956 0.31617775 0.474930695 0.418763478 0.570002869 0.902952399 0.545102825 0.346944468 1 9.003158467 -7.494255821 2.512675323 0.926209516 0.528575875 0 0.236163241 0.155694839 1.940992972 0.031162194 0.034034319 3.20E-08 7.494255821 -0.397633642 DVQMLQDAISK ddPTM_HeLa_Curcumin_4h_R1 1 DVQMLQDAISK 11 0 K7EQA9;Q16543;K7EIU0;K7EL68 K7EQA9 CDC37 "Hsp90 co-chaperone Cdc37;Hsp90 co-chaperone Cdc37, N-terminally processed" 0 0 164.33 0.0014415 11837000 766.61 548.88 678.65 669.07 599.17 941.05 675.47 680.99 851.68 749.66 FALSE FALSE TRUE 705.9320096 596.3227414 703.801366 666.3015656 592.0252891 745.8656222 694.4218703 888.6207161 758.2528348 775.7106292 0.910045554 0.768743806 0.907298855 0.858956343 0.763203786 0.961525592 0.895207367 1.145556968 0.97749445 1 9.59937476 -4.257760687 24.21154325 0.918422592 1.145557103 0.451120538 0.079226221 196.7209148 1294639.494 0.012337447 0.121584922 5.52E-05 4.257760687 0.227134511 DVS(ph)NICAPMT(ph)ASNT(ph)QDR ddPTM_HeLa_Curcumin_4h_R1 1 DVSNICAPMTASNTQDR 17 0 Q86SJ6 Q86SJ6 DSG4 Desmoglein-4 3 0 DVS(1)NICAPMT(0.79)AS(0.263)NT(0.947)QDR 45.436 0.0096669 0 299.95 359.76 441.57 386.89 257.29 503.92 387.61 407.65 367.49 758.78 TRUE FALSE FALSE 276.208641 390.8560513 457.9349726 385.2891517 254.2219848 399.4013117 398.4852934 531.9406084 327.1772664 785.1475485 0.351792019 0.497812229 0.583247026 0.49072197 0.323788803 0.508695865 0.507529182 0.677504005 0.416708002 1 9.616819987 -9.363943147 0.994193432 1.011902954 0.48132626 0 0.202128347 0.203358567 0.346720866 0.079107351 0.018766741 4.33E-10 9.363943147 -0.530576694 DVS(ph)SPDENNGQSK ddPTM_HeLa_Curcumin_4h_R1 1 DVSSPDENNGQSK 13 0 J3QL74;J3QLI2;O43829 J3QL74 ZBTB14 Zinc finger and BTB domain-containing protein 14 1 0 DVS(0.626)S(0.374)PDENNGQSK 190.37 8.10E-06 13085000 12685 11156 11997 11878 12348 13227 10450 7015.4 13569 11935 TRUE FALSE FALSE 11680.96886 12120.27493 12441.61937 11828.85198 12200.75816 10483.5711 10743.19888 9154.363165 12080.51465 12349.74036 0.945847323 0.981419412 1.007439753 0.957821917 0.987936411 0.84889 0.869912934 0.741259565 0.978199889 1 13.59219309 -4.476126366 0.906797516 0.977944346 0.675009674 0.868056783 0.02951491 0.435145155 0.329781834 0.004941119 0.120182857 3.34E-05 4.476126366 -0.302934672 DVSGFSDPYCLLGIEQGVGVPGGS(ph)PGSR ddPTM_HeLa_Curcumin_4h_R1 1 DVSGFSDPYCLLGIEQGVGVPGGSPGSR 28 0 K7EIH3;K7EQ37;K7EN81;Q70J99-2;Q70J99;Q70J99-3 K7EIH3 UNC13D Protein unc-13 homolog D 1 0 DVSGFSDPYCLLGIEQGVGVPGGS(0.5)PGS(0.5)R 127.4 1.38E-10 2342400 817.65 614.59 870.37 938.9 893.89 890.05 680.86 502.44 758.02 949.2 TRUE FALSE FALSE 752.9321397 667.712421 902.6266779 935.0150806 883.2309456 705.4435971 699.9630992 655.6316431 674.8671025 982.1846293 0.766589211 0.679823733 0.918998985 0.951974866 0.899251443 0.718239296 0.71265939 0.667523827 0.68710819 1 9.939850435 -13.52287875 0.248173248 2.325522472 0.767449189 0 0.139201864 38.9834498 0.514184218 25.29213655 0.06531479 3.00E-14 13.52287875 -1.558073283 DVSS(ph)PDENNGQSK ddPTM_HeLa_Curcumin_4h_R1 1 DVSSPDENNGQSK 13 0 J3QL74;J3QLI2;O43829 J3QL74 ZBTB14 Zinc finger and BTB domain-containing protein 14 1 0 DVS(0.001)S(0.999)PDENNGQSK 169.58 0.00019315 13490000 4471.2 4056 3896.3 4179.3 4141.9 4984.1 3543.2 2709.9 5194.7 4453.5 TRUE FALSE FALSE 4117.299802 4406.582567 4040.700306 4162.007164 4092.510548 3950.341478 3642.612656 3536.136035 4624.854406 4608.258794 0.893461063 0.956235916 0.876838842 0.903162637 0.888081753 0.857230823 0.790453145 0.767347537 1.003601276 1 12.17000602 -1 0.140031766 1.01517962 0.18415134 0.866134959 0.027293693 23.05425966 0.213283304 0.08586504 3.850654232 0.1 1 -0.83102828 SGAISAIK(ac)AETK ddPTM_HeLa_Curcumin_4h_R1 1 SGAISAIKAETK 12 1 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 0 1 SGAISAIK(1)AETK 142.91 0.00010192 1438600 575.47 579.55 686.54 674.99 601.35 826.19 356.75 187.9 887.81 721.61 FALSE TRUE FALSE 529.9209423 629.6437196 711.9837763 672.1970702 594.179294 654.8288809 366.7594449 245.189845 790.4194642 746.6858938 0.709697273 0.843251124 0.953525147 0.900240752 0.795755349 0.876980383 0.491183037 0.328370801 1.058570238 1 9.544357666 -4.655235331 3.196815724 0.864906607 0.35117478 0.794804727 0.098628857 0.092738603 1.794309282 0.015758971 0.075435581 2.21E-05 4.655235331 -0.513731827 down DVT(ph)PPPETEVVLIK ddPTM_HeLa_Curcumin_4h_R1 3 DVTPPPETEVVLIK 14 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 DVT(0.999)PPPET(0.001)EVVLIK;DVT(1)PPPETEVVLIK;DVT(1)PPPETEVVLIK ;; 156.6 0.0010715 460486000 15702.7 12726.9 14986.3 14770.6 18342.3 17516 15331.8 15905.3 13286.4 11839.7 TRUE FALSE FALSE 14459.81473 13826.95653 15541.70546 14709.48317 18123.58005 13882.98415 15761.96904 20754.75275 11828.91516 12251.12869 1.180284289 1.128627155 1.268593764 1.200663509 1.479339619 1.133200418 1.286572808 1.694109438 0.965536765 1 13.58062705 -1 0.150437864 0.962528326 2.927138008 0.627615298 0.126237365 34.76578333 0.337878764 0.261265274 14.97987305 0.1 1 1.964609682 DVTLENLALMSS(ph)LGK ddPTM_HeLa_Curcumin_4h_R1 1 DVTLENLALMSSLGK 15 0 M0R2C3 M0R2C3 ZNF552 1 0 DVTLENLALMS(0.26)S(0.74)LGK 71.286 0.01306 14943000 1249.5 843.74 1079 1086.4 1175.8 1134.5 922.26 844.78 1046.3 1263.2 TRUE FALSE FALSE 1150.600757 916.669126 1118.988689 1081.904765 1161.779353 899.1919115 948.1361335 1102.349533 931.5235077 1307.096106 0.8802725 0.70130201 0.856087539 0.827716309 0.888824737 0.687930985 0.725375991 0.843357675 0.712666424 1 10.35214951 -8.180902499 0.471213889 1.01121295 0.776196387 0 0.111950699 0.503296978 0.258003285 0.050194152 0.0251764 6.59E-09 8.180902499 -0.235016563 DVTNFTVGGFAPMS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 DVTNFTVGGFAPMSPR 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 0 DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR;DVTNFTVGGFAPMS(1)PR ;;; 218.64 2.55E-15 769440000 10176.5 7932.83 8529.18 9216.7 8971.9 12064.7 8584.09 6241.79 10141.4 8989.9 TRUE FALSE FALSE 9371.019287 8618.508477 8845.278914 9178.563738 8864.915952 9562.345223 8824.936463 8144.883037 9028.913793 9302.298356 1.007387522 0.926492373 0.950870266 0.98669849 0.952981254 1.02795512 0.948683446 0.875577489 0.970611073 1 13.1833715 -4.389935906 3.168401701 0.99082433 0.872102503 0.457746674 0.03087188 0.165332152 2.661639923 0.004538933 0.039907933 4.07E-05 4.389935906 -0.118721827 DVTNNVHYENYR ddPTM_HeLa_Curcumin_4h_R1 2 DVTNNVHYENYR 12 0 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181 G3V1Q4 7-Sep Septin-7 0 0 ; ; 162.49 0.00012569 17283000 5712.5 4407.9 4980 5683.6 5848.5 6902.6 5286.1 7254.5 5480.2 4918.3 FALSE FALSE TRUE 5260.349597 4788.899235 5164.563181 5660.082769 5778.760457 5470.922952 5434.413739 9466.363654 4879.035771 5089.210559 1.033627816 0.940990588 1.014806348 1.112173038 1.135492507 1.075004244 1.067830399 1.860084888 0.958701888 1 12.31322617 -4.259425573 4.852827692 1.030486625 1.905956615 0.94710728 0.05835258 0.028161174 1.925740204 0.008297837 0.082880471 5.50E-05 4.259425573 0.875469991 DVTTPGHST(ph)PVPDGK ddPTM_HeLa_Curcumin_4h_R1 1 DVTTPGHSTPVPDGK 15 0 F8VRB8;H0YHC1;A0A3B3IS46;A0A3B3IRX3;Q71F56 F8VRB8 MED13L Mediator of RNA polymerase II transcription subunit 13-like 1 0 DVTTPGHS(0.095)T(0.905)PVPDGK 86.573 0.0099495 7970900 7386.8 5494.3 6733.2 7149.7 6555.8 8377.5 5432.6 7011.2 6984 5734.6 TRUE FALSE FALSE 6802.126985 5969.20281 6982.738315 7120.116436 6477.626367 6639.912066 5585.024135 9148.882604 6217.872673 5933.876923 1.146320875 1.005953256 1.176758198 1.199909693 1.091634769 1.118983786 0.941209972 1.541805252 1.047860067 1 12.53475929 DVTVLS(ph)VAEEQDLLKQER ddPTM_HeLa_Curcumin_4h_R1 1 DVTVLSVAEEQDLLKQER 18 1 Q14966-3;Q14966;Q14966-5;A0A096LPK8 Q14966-3 ZNF638 Zinc finger protein 638 1 0 DVT(0.001)VLS(0.999)VAEEQDLLKQER 103.4 0.00048908 3921700 1321.4 1084.9 1132.2 1260.1 1134.3 2016.7 1682 786.63 1626.3 1436 TRUE FALSE FALSE 1216.809796 1178.673922 1174.160328 1254.88604 1120.774213 1598.413687 1729.192393 1026.469866 1447.898959 1485.900893 0.818903738 0.793238585 0.790200971 0.844528761 0.754272521 1.075720255 1.163733329 0.690806413 0.974424987 1 10.53712218 -3.987750315 17.456361 0.905126896 0.340140636 0.205533951 0.130143415 11230483.45 279641902.2 0.019154475 155527683.5 0.000102861 3.987750315 -0.56498626 DVVICPDASLEDAKK ddPTM_HeLa_Curcumin_4h_R1 3 DVVICPDASLEDAKK 15 1 Q99497;K7ELW0;K7EN27 Q99497 PARK7 Protein deglycase DJ-1 0 0 ;; ;; 166.03 6.10E-05 54965200 10167.4 9101.6 9002.3 9241.2 9239.8 11490.7 9360.6 9606.9 9735.9 7565.3 FALSE FALSE TRUE 9362.639561 9888.301748 9335.933157 9202.962363 9129.62142 9107.399293 9623.233243 12535.99959 8667.896128 7828.193612 1.196015329 1.2631652 1.192603763 1.175617623 1.166248802 1.163410072 1.22930445 1.601391101 1.107266447 1 12.93446372 -1 0.04492966 0.466447372 2.515158296 0.452531506 0.10894624 347.6422002 1.19689675 14.0579418 51.84363715 0.1 1 2.048710924 DVVLSTS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 DVVLSTSPK 9 0 Q9P275;A0A075B784 Q9P275 USP36 Ubiquitin carboxyl-terminal hydrolase 36;Ubiquitin carboxyl-terminal hydrolase 1 0 DVVLS(0.053)T(0.356)S(0.591)PK;DVVLS(0.096)T(0.357)S(0.547)PK ; 119.34 0.0064073 88528000 30417 28038 28934 29923 27102 31722 21999 15205.1 32461 24738 TRUE FALSE FALSE 28009.46235 30461.47979 30006.31949 29799.18655 26778.82635 25142.49962 22616.23273 19841.06499 28900.10951 25597.64366 1.09422034 1.190011088 1.172229753 1.164137877 1.046144196 0.982219299 0.883527915 0.775112946 1.129014448 1 14.64372339 -4.712015625 1.543101799 1.075867942 0.766063239 0.7564167 0.063540983 0.270175053 1.016676295 0.011679087 0.098049471 1.94E-05 4.712015625 -0.309804703 DVVMLDNLPDLPPALVPS(ph)PPKR ddPTM_HeLa_Curcumin_4h_R1 2 DVVMLDNLPDLPPALVPSPPKR 22 1 H3BPY8;H3BPM3;H3BRE8;Q9BWH6-2;Q9BWH6 H3BPY8 RPAP1 RNA polymerase II-associated protein 1 1 0 DVVMLDNLPDLPPALVPS(1)PPKR;DVVMLDNLPDLPPALVPS(1)PPKR ; 74.516 0.0010407 73851000 3443.9 2825.4 3152.7 2937.4 3045.6 3391.1 2772.8 2494.7 3692.5 2966 TRUE FALSE FALSE 3171.311681 3069.614986 3269.541835 2925.245817 3009.283209 2687.747634 2850.597305 3255.322546 3287.441988 3069.068279 1.03331415 1.000178135 1.065320657 0.95313807 0.980520124 0.875753613 0.928815212 1.06068756 1.071153096 1 11.58358503 -6.227515121 23.28480026 1.018098391 0.954546227 0.333308449 0.049737232 257.1686158 176513.9181 0.006850598 0.011359755 5.92E-07 6.227515121 -0.063552164 DVVQAYPEVR ddPTM_HeLa_Curcumin_4h_R1 1 DVVQAYPEVR 10 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 0 96.331 0.011983 31126000 3278 3120 2951.9 3772.8 3781.8 4745.3 3802.1 3412 3836.4 3004.4 FALSE FALSE TRUE 3018.542841 3389.678898 3061.300011 3757.189153 3736.704505 3761.071289 3908.776693 4452.303093 3415.556518 3108.802676 0.970966367 1.090348681 0.984719948 1.208564693 1.201975453 1.209813449 1.25732544 1.432160081 1.098672664 1 11.60214333 -4.920426219 0.441259139 0.978081566 1.533544015 0.774003557 0.065303318 0.725817208 0.138804919 0.013892007 0.190463576 1.20E-05 4.920426219 0.55546245 FSSVSS(ph)PQPR ddPTM_HeLa_Curcumin_4h_R1 2 FSSVSSPQPR 10 0 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 1 0 FSSVS(0.027)S(0.973)PQPR;FS(0.001)SVS(0.156)S(0.843)PQPR ; 118.77 0.0047802 78141000 9690.1 8058.9 8142.6 7827.3 7674.4 7575.6 4934.3 2586.6 9685 7020.7 TRUE FALSE FALSE 8923.11836 8755.475406 8444.371919 7794.912707 7582.887792 6004.335165 5072.743178 3375.242433 8622.579731 7264.668802 1.228289768 1.205213292 1.162389112 1.072989412 1.043803647 0.826511893 0.698275904 0.464610642 1.186919867 1 12.82668131 -4.749295886 1.04661213 1.123245506 0.389857999 0.921746157 0.066747449 0.257593954 0.359922792 0.014719374 0.173016599 1.78E-05 4.749295886 -0.733387507 down DVYLS(ph)PRDDGYSTK ddPTM_HeLa_Curcumin_4h_R1 1 DVYLSPRDDGYSTK 14 1 P38159;P38159-2;H3BUY5;Q96E39;H0Y6E7;H3BT71 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 1 0 DVY(0.004)LS(0.985)PRDDGY(0.007)S(0.003)T(0.001)K 62.203 0.020111 1187800000 2870.7 2169.7 2157.4 2910.5 2016.9 4069.5 2419.3 1336.3 4463.2 3754.1 TRUE FALSE FALSE 2643.481066 2357.2392 2237.355142 2898.457122 1992.849785 3225.439827 2487.179047 1743.731718 3973.598126 3884.554696 0.680510708 0.606823532 0.575961807 0.746149134 0.513018851 0.830324215 0.640273916 0.448888445 1.022922429 1 11.92353351 -8.950830057 0.554928933 1.038413063 0.623208644 0.685265635 0.103294088 0.502185291 0.258493617 0.105024373 0.02529497 1.12E-09 8.950830057 -0.415204419 DVYRAGIATHFVDS(ph) ddPTM_HeLa_Curcumin_4h_R1 1 DVYRAGIATHFVDS 14 1 B8ZZZ0 B8ZZZ0 HIBCH 1 0 DVYRAGIAT(0.002)HFVDS(0.998) 66.498 0.016728 23549000 1884.1 1841.1 1584.4 1376.9 1870 2176.5 1861.9 1632.7 2145.8 1621.8 TRUE FALSE FALSE 1734.971497 2000.23648 1643.119258 1371.202753 1847.701471 1725.069366 1914.139903 2130.502714 1910.411109 1678.157429 1.033855029 1.191924217 0.979121046 0.817088271 1.101029879 1.027954431 1.140619986 1.269548778 1.138398028 1 10.71266235 -4.397477901 1.571837388 1.016930879 1.327115813 0.351580052 0.097135129 0.572289638 1.604944811 0.012762291 0.25001622 4.00E-05 4.397477901 0.310184935 DVYVTTHT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 DVYVTTHTPR 10 0 P78317;D6RA71;H0YAI5 P78317 RNF4 E3 ubiquitin-protein ligase RNF4 1 0 DVYVTT(0.016)HT(0.984)PR 91.307 0.01743 6711700 4475.2 3553 3993.6 3750.3 4787.2 6126.6 5517 3169.9 4209.5 3657.8 TRUE FALSE FALSE 4120.983198 3860.105488 4141.606329 3734.782252 4730.115767 4855.874099 5671.792172 4136.387918 3747.728382 3784.908278 1.088793412 1.019867644 1.094242192 0.986756343 1.249730619 1.282956876 1.498528301 1.09286345 0.990176804 1 11.88604262 -5.651907423 4.574958222 1.042122548 1.305389599 0.608660258 0.098315674 0.099672076 3.560305433 0.013127872 0.026789716 2.23E-06 5.651907423 0.263267051 DWEDDS(ph)DEDMSNFDR ddPTM_HeLa_Curcumin_4h_R1 13 DWEDDSDEDMSNFDR 15 0 A0A087WYT3;Q15185-4;Q15185;Q15185-2;B4DDC6 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 1 0 DWEDDS(0.999)DEDMS(0.001)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.999)DEDMS(0.001)NFDR;DWEDDS(0.992)DEDMS(0.008)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.996)DEDMS(0.004)NFDR;DWEDDS(0.999)DEDMS(0.001)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(0.999)DEDMS(0.001)NFDR;DWEDDS(1)DEDMSNFDR;DWEDDS(1)DEDMSNFDR ;;;;;;;;;;;; 270.21 8.30E-51 4100931000 37985.16 37019.67 40741.78 36125.13 42673.13 53535.88 45640.92 43406.13 34348.2 36830.96 TRUE FALSE FALSE 34978.5945 40219.48532 42251.70621 35975.65378 42164.2808 42431.93501 46921.48138 56640.45922 30580.28839 38110.83312 0.917812381 1.05532947 1.108653439 0.943974478 1.106359461 1.113382509 1.231184877 1.486203648 0.802404091 1 15.21791353 -1 0.488065819 0.969482012 16.21029046 0.816026536 0.076637084 21.42589916 0.212009046 0.012080531 334.9831144 0.1 1 15.24080844 DWEDDSDEDMSNFDR ddPTM_HeLa_Curcumin_4h_R1 2 DWEDDSDEDMSNFDR 15 0 A0A087WYT3;Q15185-4;Q15185;Q15185-2;B4DDC6 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 0 0 ; ; 318.91 1.47E-107 70774000 4652.2 3859.3 4375.7 4265.3 4689.9 6705.1 5014.1 3953.3 3909.3 3720.8 FALSE FALSE TRUE 4283.973461 4192.880695 4537.867291 4247.651319 4633.976006 5314.386678 5154.782151 5158.642971 3480.459571 3850.097523 1.112692194 1.089032335 1.178636973 1.103258111 1.203599643 1.380325212 1.33887054 1.339873325 0.903992574 1 11.91067927 -4.07790858 0.240632709 0.999277596 1.751476126 0.831759936 0.06035529 3.069648847 0.134459008 0.038802763 0.700457358 8.36E-05 4.07790858 0.75219853 DWEQFHQPR ddPTM_HeLa_Curcumin_4h_R1 2 DWEQFHQPR 9 0 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 0 0 ; ; 115.23 0.0059628 18640900 8046.5 6476.6 7705.7 7124.5 8596.7 8963 7312.2 7057.2 6968.1 6924.8 FALSE FALSE TRUE 7409.611034 7036.408445 7991.280021 7095.020707 8494.189967 7103.972766 7517.360652 9208.907793 6203.716863 7165.436285 1.034076746 0.981993024 1.115253797 0.990172883 1.185439327 0.991422222 1.049114158 1.28518452 0.86578355 1 12.80683883 -4.264555496 4.570872278 1.029677224 1.300870459 0.487795503 0.080411559 0.091244041 4.950831054 0.007949268 0.078865028 5.44E-05 4.264555496 0.271193235 DWGEHNQR ddPTM_HeLa_Curcumin_4h_R1 1 DWGEHNQR 8 0 Q14151 Q14151 SAFB2 Scaffold attachment factor B2 0 0 109.48 0.0053116 0 2926.8 2508.4 2559.8 2333.1 2763.3 3309.2 2201.5 2372.5 2728.3 2440.3 FALSE FALSE TRUE 2695.140692 2725.214919 2654.66844 2323.44625 2730.349452 2622.834618 2263.268165 3095.864328 2429.012316 2525.100243 1.067340078 1.079250191 1.0513121 0.920140203 1.081283588 1.038705146 0.896308244 1.226036208 0.961946886 1 11.30212495 DWILPSDYDHAEAEAR ddPTM_HeLa_Curcumin_4h_R1 3 DWILPSDYDHAEAEAR 16 0 O43852-2;O43852;O43852-4;O43852-3;O43852-9;O43852-5;H0Y875;O43852-15 O43852-2 CALU Calumenin 0 0 ;; ;; 217.01 2.54E-15 17773000 8722.4 8433.6 9269.3 8244.2 11224.1 10622.1 6971.3 5295.9 8765.9 7503.8 FALSE FALSE TRUE 8032.012836 9162.562805 9612.828412 8210.087685 11090.25994 8418.956724 7166.895916 6910.595531 7804.302701 7764.556491 1.034445798 1.180049732 1.2380396 1.057380121 1.428318533 1.084280439 0.923027081 0.890018063 1.005118929 1 12.92268781 -2.844935533 13.55428862 1.061475907 1.089396552 0 0.153817007 0 0 0.02105973 0 0.001429106 2.844935533 0.027920645 DWQSYYYHHPQDR ddPTM_HeLa_Curcumin_4h_R1 1 DWQSYYYHHPQDR 13 0 Q1KMD3 Q1KMD3 HNRNPUL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 0 71.529 0.009765 5421400 2455.7 2118.2 2046.8 2161.9 2417.2 5525.5 4016.1 2383.4 2617.9 1990.6 FALSE FALSE TRUE 2261.328754 2301.287769 2122.656209 2152.954631 2388.376469 4379.449015 4128.780957 3110.087688 2330.72292 2059.773202 1.097853274 1.11725299 1.030529093 1.045238684 1.159533713 2.126180208 2.004483287 1.509917541 1.131543472 1 11.00826978 -5.341129084 5.674864615 1.054750063 1.890302001 0.850463265 0.153118951 0.052379829 2.8598763 0.020684302 0.047076528 4.56E-06 5.341129084 0.835551939 DWSHYFK ddPTM_HeLa_Curcumin_4h_R1 2 DWSHYFK 7 0 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 0 0 ; ; 94.662 0.018314 49467000 30276 21774 25757 25754 27051 30551 24313 20311 24716 23914 FALSE FALSE TRUE 27879.62265 23656.04754 26711.57708 25647.43677 26728.43449 24214.37822 24995.15734 26503.7304 22004.71664 24745.00972 1.126676569 0.955992655 1.079473291 1.036469052 1.080154536 0.97855602 1.010109013 1.071073752 0.889258759 1 14.59484999 -5.276479773 24.85731045 1.054007342 1.018932531 0 0.07142352 1589.855783 2627560.954 0.008296503 0.018620445 5.29E-06 5.276479773 -0.035074811 DY(ph)IRTQIISKKINTK ddPTM_HeLa_Curcumin_4h_R1 1 DYIRTQIISKKINTK 15 3 O00232-2;O00232 O00232-2 PSMD12 26S proteasome non-ATPase regulatory subunit 12 1 0 DY(0.849)IRT(0.151)QIISKKINTK 47.774 0.019464 781070 640.98 376.32 372.63 496.69 595.13 948.02 464.31 487.37 548.57 724.73 TRUE FALSE FALSE 590.2457566 408.847424 386.4399956 494.6348284 588.0334634 751.3899656 477.337289 635.9668694 488.3932435 749.9143136 0.787084265 0.545192186 0.515312201 0.659588462 0.784134204 1.001967761 0.63652244 0.848052715 0.651265397 1 9.55058195 -8.465859867 1.006799291 0.971460914 0.718965356 0 0.170580611 0.396108774 0.823177552 0.050708965 0.030100874 3.42E-09 8.465859867 -0.252495558 DYAFIHFDER ddPTM_HeLa_Curcumin_4h_R1 3 DYAFIHFDER 10 0 O60506-4;O60506-3;O60506-2;O60506;B7Z645;O60506-5 O60506-4 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 0 ;; ;; 149.33 0.00067336 90928000 30965.3 27196.3 29110.4 28348.4 32820.5 36165.5 30153.3 27690.3 29038.6 24972.7 FALSE FALSE TRUE 28514.36383 29547.02699 30189.25703 28231.10183 32429.13697 28664.36763 30999.32044 36132.945 25853.13823 25840.49947 1.103475723 1.143438695 1.168292318 1.092513783 1.254973303 1.109280711 1.199640916 1.398306757 1.000489107 1 14.65734634 -1 0.131964196 0.954724579 2.105014761 0.694788277 0.062359637 33.66883514 0.298477494 0.196403948 7.253617928 0.1 1 1.150290183 DYAFVHFEDR ddPTM_HeLa_Curcumin_4h_R1 2 DYAFVHFEDR 10 0 O43390;B4DT28;O43390-4;O43390-3;O43390-2;A0A286YEZ8 O43390 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 0 ; ; 107.03 0.0070939 116390000 18407.3 14748.7 16775.8 17361.8 16618.1 22339 18126 16076.7 18010.7 15903.2 FALSE FALSE TRUE 16950.34278 16023.51191 17397.52591 17289.96147 16419.94001 17705.63959 18634.56678 20978.41182 16034.97127 16455.83502 1.030050603 0.973728279 1.057225348 1.050688795 0.997818707 1.075949022 1.132398736 1.274831195 0.97442465 1 14.00631161 -3.766622397 0.862319697 1.014545013 1.692604938 0.897833772 0.02763759 0.902273617 0.27537768 0.003865432 0.709516483 0.00017115 3.766622397 0.678059924 DYAPPPR ddPTM_HeLa_Curcumin_4h_R1 1 DYAPPPR 7 0 P38159;P38159-2;H3BUY5;Q96E39;H0Y6E7;H3BT71 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 0 0 101.21 0.02034 2351000 1586.6 1325.4 1364.7 1442.7 1352.8 1842.4 1557.7 1324.1 1468.6 1371.6 FALSE FALSE TRUE 1461.018936 1439.96167 1415.276983 1436.73049 1336.668744 1460.265472 1601.40487 1727.811995 1307.498254 1419.262998 1.02942086 1.014584099 0.997191489 1.012307438 0.941804828 1.028889976 1.128335532 1.21740086 0.921251562 1 10.47092624 -4.589114176 2.399418709 1.007930197 1.215055725 0.807912533 0.035851675 0.076890788 0.78572483 0.003558233 0.02450867 2.58E-05 4.589114176 0.207125528 DYDDMS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 9 DYDDMSPR 8 0 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 0 DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR;DYDDMS(1)PR ;;;;;;;; 151.83 0.0017395 13629684000 59689.4 52466 51159.4 53561.3 52040.1 64716.8 53367.6 32668.9 59964.5 50888.2 TRUE FALSE FALSE 54964.92101 57000.92726 53055.41237 53339.67753 51419.5558 51293.80617 54864.95122 42629.49722 53386.54437 52656.56116 1.043838029 1.082503794 1.007574578 1.012973053 0.976508049 0.974119939 1.041939504 0.809576172 1.013863101 1 15.68432569 -4.257581479 24.96989394 1.018827012 0.80957609 0.80219802 0.030893483 130.7479762 846218.5564 0.004633883 0.046480569 5.53E-05 4.257581479 -0.209250922 DYDDMSPR ddPTM_HeLa_Curcumin_4h_R1 2 DYDDMSPR 8 0 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 0 ; ; 137 0.0009844 6992200 7257.6 5207.13 5737 6369.3 5571.6 6571.6 5407.4 5719.37 7118 6155.3 FALSE FALSE TRUE 6683.153302 5657.211115 5949.618267 6342.945524 5505.162309 5208.576083 5559.117091 7463.179584 6337.173208 6369.196217 1.049293046 0.888214293 0.934123878 0.995878492 0.864341766 0.817776044 0.872812974 1.171761605 0.994972206 1 12.6368956 -7.266376143 24.91493043 1.023277273 0.927679242 0.12806678 0.093245291 489.8016435 2471933.205 0.015390946 0.017896295 5.42E-08 7.266376143 -0.09559803 DYDEEEQGYDS(ph)EK ddPTM_HeLa_Curcumin_4h_R1 2 DYDEEEQGYDSEK 13 0 Q5T757;Q05519-2;Q05519 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 0 DYDEEEQGYDS(1)EK;DYDEEEQGYDS(1)EK ; 177.88 0.00018918 40089000 3710.7 2868.5 3546.2 3145.4 3856 3894.1 3099.19 3518.1 3046.12 2710.58 TRUE FALSE FALSE 3416.994179 3116.440358 3677.625292 3132.385168 3810.019718 3086.419764 3186.14493 4590.752495 2711.968257 2804.772453 1.218278572 1.111120567 1.311202728 1.116805452 1.358405996 1.10041717 1.135972698 1.636764683 0.966912041 1 11.45366802 -1.000030457 0.028291541 3.06E-10 2.944011772 0.419960774 0.142793661 1116.368339 2.449262345 83.93011131 191.8398245 0.099992987 1.000030457 2.944011772 DYDEEEQGYDS(ph)EKEKK ddPTM_HeLa_Curcumin_4h_R1 1 DYDEEEQGYDSEKEKK 16 2 Q5T757;Q05519-2;Q05519 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 0 DYDEEEQGY(0.003)DS(0.997)EKEKK 71.872 0.016315 126530000 4578.9 4199.4 4932.1 4831.4 5812.7 5514.4 5169.3 5330.4 5291.9 4849.8 TRUE FALSE FALSE 4216.475233 4562.377424 5114.887965 4811.408947 5743.387349 4370.65128 5314.336646 6955.614422 4711.39181 5018.330189 0.840214788 0.909142534 1.019241017 0.958766914 1.144481756 0.870937367 1.05898505 1.386041603 0.938836552 1 12.29299168 -1.319664154 0.986491652 0.938775279 199.9999995 0.688851916 0.08423308 324.6869697 0.924689796 0.014332284 145408.7228 0.047900037 1.319664154 199.0612242 DYEDGMEVDTTPTVAGQFEDADVDH ddPTM_HeLa_Curcumin_4h_R1 5 DYEDGMEVDTTPTVAGQFEDADVDH 25 0 P54105;E9PMI6;J3KN38 P54105 CLNS1A Methylosome subunit pICln 0 0 ;;;; ;;;; 175.77 3.91E-13 23446100 10072.3 9087.6 9435.94 9290.9 10674.12 10868.2 8690.59 8383.02 8782.39 8710.55 FALSE FALSE TRUE 9275.066827 9873.09165 9785.644237 9252.456718 10546.83809 8614.01281 8934.424566 10938.96421 7818.983789 9013.240964 1.029049025 1.095398613 1.085696508 1.026540481 1.170149354 0.955706482 0.991255488 1.213654916 0.867499695 1 13.13783025 -7.498985234 3.097970602 1.011567925 1.070862005 0.209815337 0.085848443 0.382890972 7.322290135 0.012574773 0.013756508 3.17E-08 7.498985234 0.05929408 DYEEVGADS(ph)ADGEDEGEEY ddPTM_HeLa_Curcumin_4h_R1 1 DYEEVGADSADGEDEGEEY 19 0 Q9BQE3;F5H5D3 Q9BQE3 TUBA1C Tubulin alpha-1C chain 1 0 DYEEVGADS(1)ADGEDEGEEY 201.06 2.84E-13 8541900 11795 10588 10969 10551 12580 11904 9629.1 11097 9826.1 9634.9 TRUE FALSE FALSE 10861.4133 11503.17954 11375.52079 10507.34276 12429.99172 9434.976214 9899.266631 14480.42422 8748.201414 9969.712058 1.089441023 1.153812615 1.141007957 1.053926402 1.246775398 0.946363963 0.992934056 1.452441568 0.877477841 1 13.28333612 -2.44271796 0.017850723 1.72E-06 2.41341842 0.247925593 0.136278977 3713.328567 6.674235956 367.9384379 551.361916 0.003608129 2.44271796 2.413416696 DYEEVGADSADGEDEGEEY ddPTM_HeLa_Curcumin_4h_R1 6 DYEEVGADSADGEDEGEEY 19 0 Q9BQE3;F5H5D3 Q9BQE3 TUBA1C Tubulin alpha-1C chain 0 0 ;;;;; ;;;;; 275.57 1.24E-67 180743300 43960.6 38829 39646.6 38874.4 44416.4 43341.7 34604 33166.5 36553 34016.2 FALSE FALSE TRUE 40481.07212 42185.20574 41115.93787 38713.54803 43886.76344 34352.14286 35574.89511 43278.81317 32543.22735 35198.26042 1.150087295 1.198502575 1.168124145 1.099871061 1.246844671 0.975961381 1.010700378 1.229572503 0.924569196 1 15.10321651 -9.21680503 0.984249916 1.000979142 1.131350274 0.362710386 0.087208653 0.599224783 1.054223503 0.053621418 0.015405776 6.07E-10 9.21680503 0.130371132 DYEEVGVDSVEGEGEEEGEEY ddPTM_HeLa_Curcumin_4h_R1 4 DYEEVGVDSVEGEGEEEGEEY 21 0 P68363;P68363-2 P68363 TUBA1B Tubulin alpha-1B chain 0 0 ;;; ;;; 220.23 6.57E-22 81538100 65386 55100 58439 55932.6 66397.9 64718.4 51263.4 49364.4 54561.2 51450.9 FALSE FALSE TRUE 60210.62911 59862.59848 60604.80075 55701.16572 65606.14841 51295.07431 52701.71304 64415.37831 48575.97287 53238.81495 1.130953594 1.124416435 1.138357434 1.046251044 1.232299188 0.96349016 0.98991146 1.20993261 0.912416494 1 15.70019084 -9.368487795 1.084493609 0.999827637 1.102190679 0.287676133 0.086522976 0.697313159 1.463353501 0.054140436 0.013913991 4.28E-10 9.368487795 0.102363042 DYEIESQNPLAS(ph)PTNTLLGSAK ddPTM_HeLa_Curcumin_4h_R1 2 DYEIESQNPLASPTNTLLGSAK 22 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 DYEIESQNPLAS(0.807)PT(0.188)NT(0.005)LLGSAK;DYEIESQNPLAS(0.618)PT(0.374)NT(0.008)LLGSAK ; 116.27 3.98E-06 249260000 13676.7 10593.4 11756.5 12568.6 12639.8 16526.9 14970.7 18095.1 14083.3 12347.6 TRUE FALSE FALSE 12594.17476 11509.04629 12192.20623 12516.59446 12489.07864 13099.03464 15390.73755 23612.21269 12538.39722 12776.67818 0.985715895 0.900785488 0.95425478 0.97964387 0.977490273 1.025230068 1.204596166 1.848071334 0.98135032 1 13.64122518 -4.171396402 1.768534675 0.981221771 2.283345568 0.987965474 0.029058845 0.094971937 0.244061983 0.004745191 0.221691194 6.74E-05 4.171396402 1.302123797 DYETATLSDIK ddPTM_HeLa_Curcumin_4h_R1 1 DYETATLSDIK 11 0 O43707;O43707-2 O43707 ACTN4 Alpha-actinin-4 0 0 161.51 0.0027548 4728800 2292.8 1355.7 1932.1 1547 2140.6 3046.7 2227.4 1698.8 1874.2 1729.5 FALSE FALSE TRUE 2111.322461 1472.880667 2003.705326 1540.598924 2115.074743 2414.780077 2289.894849 2216.7563 1668.604949 1789.599996 1.179773394 0.823022279 1.119638651 0.860862163 1.181870109 1.34934068 1.279556803 1.238688145 0.932389893 1 10.80542144 -5.526890501 24.99228566 1.052637664 1.284460394 0.552760802 0.115634138 76.72720695 477992.4163 0.016989375 0.034095442 2.97E-06 5.526890501 0.23182273 DYFEEYGKIDTIEIITDR ddPTM_HeLa_Curcumin_4h_R1 5 DYFEEYGKIDTIEIITDR 18 1 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 ;;;; ;;;; 130.47 0.00019796 32459310 2990.14 2527.84 2942.21 2320.69 2252.17 3103.86 2510.09 2616.74 2457.34 2253.91 FALSE FALSE TRUE 2753.467264 2746.335226 3051.250891 2311.0876 2225.314344 2460.084448 2580.51637 3414.57198 2187.77595 2332.233205 1.180614039 1.177556009 1.308295793 0.990933323 0.954156016 1.054819236 1.106457264 1.46407828 0.938060545 1 11.18749634 -9.328855568 1.054773099 1.000074614 1.145469676 0.199556207 0.143389849 0.90647498 1.806760961 0.097233914 0.025715286 4.69E-10 9.328855568 0.145395062 DYFEQYGK ddPTM_HeLa_Curcumin_4h_R1 2 DYFEQYGK 8 0 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8VZ49;A0A2R8Y4L2;Q32P51;F8VYN5 F8W6I7 HNRNPA1;HNRNPA1L2 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;Heterogeneous nuclear ribonucleoprotein A1-like 2" 0 0 ; ; 140.5 0.00064622 39421000 13324.6 10469.1 11835.3 9923.6 11670.5 14721.5 13686.8 12105.2 9932.9 8075.8 FALSE FALSE TRUE 12269.94385 11374.00235 12273.92663 9882.538773 11531.33691 11668.09495 14070.81477 15796.01975 8843.285721 8356.433449 1.46832305 1.361107274 1.468799662 1.182626396 1.37993523 1.396300829 1.683830172 1.890282481 1.058260773 1 13.02867161 -1.000003102 0.043692563 1.67E-08 3.888790349 0.672386605 0.14649698 313.4012475 1.050419059 24.52431549 87.30778411 0.099999286 1.000003102 3.888790332 DYGHSSSRDDYPSR ddPTM_HeLa_Curcumin_4h_R1 2 DYGHSSSRDDYPSR 14 1 P38159;P38159-2;H3BUY5;Q96E39;H0Y6E7;H3BT71 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 0 0 ; ; 99.669 0.0025171 21693000 5412.6 4005.8 3874.8 4909.4 4435.5 7805.1 4861.7 4828.1 7709.7 5113.3 FALSE FALSE TRUE 4984.186999 4352.043503 4018.403497 4889.086204 4382.609559 6186.234278 4998.106217 6300.165464 6863.965199 5290.986794 0.942014636 0.822539097 0.759480916 0.924040523 0.828316102 1.169202366 0.944645377 1.190735435 1.297293958 1 12.3693211 -5.256814207 24.99114078 0.93202796 1.085839488 0.191983861 0.1511978 374.1271005 2021507.887 0.014962184 0.036785012 5.54E-06 5.256814207 0.153811529 RGSFSS(ph)ENYWR ddPTM_HeLa_Curcumin_4h_R1 1 RGSFSSENYWR 11 1 Q6P6C2-3;Q6P6C2;K7ER58;Q6P6C2-1 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 0 RGS(0.01)FS(0.013)S(0.975)ENY(0.001)WR 110.93 0.010034 55127000 1441.4 1170 1300.5 1291.7 1278.8 1756.3 2059.7 2807.5 1168.6 1375.2 TRUE FALSE FALSE 1327.311669 1271.129587 1348.697674 1286.355288 1263.551145 1392.023582 2117.489639 3663.493826 1040.407504 1422.988098 0.932763718 0.893281953 0.94779266 0.903981762 0.887956229 0.978239793 1.488058573 2.574507708 0.731142801 1 10.47470788 -4.289274126 1.933116787 0.948387335 3.015785204 0.97627551 0.079312842 0.048901518 0.198187947 0.007307959 0.17623884 5.14E-05 4.289274126 2.067397869 up DYIAPWER ddPTM_HeLa_Curcumin_4h_R1 1 DYIAPWER 8 0 M0QZH1;M0QX70;M0QYR7;M0R2N0;M0QZC7;Q9H0W8-2;Q9H0W8 M0QZH1 SMG9 Protein SMG9 0 0 119.17 0.007964 0 1741.6 1674.1 1693.4 1846.5 1517.8 1786.1 1240.4 1180.1 1922.3 1736.4 FALSE FALSE TRUE 1603.750522 1818.801744 1756.158894 1838.859672 1499.701226 1415.642727 1275.202286 1539.907057 1711.428499 1796.739771 0.892589204 1.012278892 0.97741416 1.023442405 0.834679151 0.787895248 0.709731207 0.857056254 0.95251885 1 10.81116576 -5.595018143 4.853182205 0.960123109 0.781895702 0.759357236 0.049374333 0.089143703 3.95206238 0.008335074 0.017113569 2.54E-06 5.595018143 -0.178227406 DYIPVDQEELR ddPTM_HeLa_Curcumin_4h_R1 2 DYIPVDQEELR 11 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 0 ; ; 160.91 0.0028484 17964900 4568.4 4280.6 4242.8 4054.9 4085.4 5838.4 4594.4 3406.9 4280.9 4206.4 FALSE FALSE TRUE 4206.806319 4650.59599 4400.0419 4038.121898 4036.684273 4627.450028 4723.306499 4445.648127 3811.29598 4352.572087 0.96651043 1.068470756 1.010906152 0.927755317 0.927425024 1.06315299 1.085175938 1.021384147 0.875642242 1 12.08765248 -5.229105018 24.28140737 0.98476907 1.059431553 0.334165871 0.053690111 369.8577987 277742.852 0.006006092 0.015310725 5.90E-06 5.229105018 0.074662482 DYLDFLDDEEDQGIYQSK ddPTM_HeLa_Curcumin_4h_R1 2 DYLDFLDDEEDQGIYQSK 18 0 P25205;P25205-2 P25205 MCM3 DNA replication licensing factor MCM3 0 0 ; ; 176.94 8.07E-07 6601000 4820.4 3824.6 4574.2 4438.3 4526.6 5155.1 4566.3 3908.7 4559.5 4149 FALSE FALSE TRUE 4438.860254 4155.181382 4743.723876 4419.935491 4472.623251 4085.87415 4694.418088 5100.444637 4059.334257 4293.177441 1.033933564 0.967856894 1.10494475 1.029525462 1.041797902 0.951713319 1.093460066 1.188034901 0.945531442 1 12.06783009 -4.472302814 3.851654774 1.018527078 1.179180505 0.589370777 0.046420333 0.104274422 2.998331748 0.005303598 0.033185185 3.37E-05 4.472302814 0.160653427 DYLHLPPEIVPATLR ddPTM_HeLa_Curcumin_4h_R1 1 DYLHLPPEIVPATLR 15 0 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6;A0A2R8Y6L3 P46783 RPS10;RPS10-NUDT3 40S ribosomal protein S10 0 0 81.703 0.011526 7559700 2707.2 2027.3 2420.1 2183.5 2706.5 5312.3 3408.6 2953.3 2774.8 2250.7 FALSE FALSE TRUE 2492.922263 2202.530779 2509.791035 2174.465256 2674.226755 4210.469098 3504.236142 3853.747575 2470.411382 2328.911657 1.070423713 0.945733932 1.077666912 0.933683014 1.148273163 1.807912758 1.504666839 1.654741846 1.060757876 1 11.1854402 -5.380860034 4.823383572 1.02495753 1.637755546 0.919697106 0.084748846 0.039270873 1.384804495 0.011017203 0.025247125 4.16E-06 5.380860034 0.612798016 DYLHYIR ddPTM_HeLa_Curcumin_4h_R1 2 DYLHYIR 7 0 P62280;M0QZC5;M0R1H5 P62280 RPS11 40S ribosomal protein S11 0 0 ; ; 105.2 0.013853 40067000 27321 18097.9 22068.5 20275.3 25338.8 22139.5 19996.5 21263.2 20337.1 19943.4 FALSE FALSE TRUE 25158.51402 19662.20183 22886.37802 20191.40618 25036.65136 17547.51814 20557.54797 27746.2518 18106.17101 20636.43167 1.219131022 0.95279078 1.109027878 0.978434959 1.213225802 0.850317459 0.996177455 1.344527593 0.877388654 1 14.33290591 -7.25261264 24.81306464 1.103478539 1.056949601 0 0.157619527 2317.207683 6513971.22 0.024260437 0.02950437 5.59E-08 7.25261264 -0.046528938 DYLLS(ph)ES(ph)EDEGDNDGER ddPTM_HeLa_Curcumin_4h_R1 1 DYLLSESEDEGDNDGER 17 0 Q9BVJ6-3;Q9BVJ6 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 2 0 DY(0.336)LLS(0.664)ES(1)EDEGDNDGER 104.16 0.0037206 14038000 2468.2 2052.6 2155.2 2267.6 2306.5 2393.5 2370 2195.3 2225.2 1991.1 TRUE FALSE FALSE 2272.839366 2230.017598 2235.073608 2258.217272 2278.996494 1897.06112 2436.495821 2864.636864 1981.101127 2060.290577 1.103164472 1.082380137 1.084834165 1.096067369 1.106152947 0.920773575 1.182598148 1.390404294 0.961563941 1 11.00863211 -4.407559862 3.43988168 1.055076149 1.390845898 0.73769486 0.063252631 0.095331096 1.843629113 0.008351134 0.064868581 3.91E-05 4.407559862 0.335769749 DYLLS(ph)ES(ph)EDEGDNDGERK ddPTM_HeLa_Curcumin_4h_R1 2 DYLLSESEDEGDNDGERK 18 1 Q9BVJ6-3;Q9BVJ6 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 2 0 DY(0.008)LLS(0.994)ES(0.998)EDEGDNDGERK;DY(0.096)LLS(0.952)ES(0.952)EDEGDNDGERK ; 76.533 0.0035231 59298000 10131.1 9550.9 10227.8 9748.8 12420.6 11380.2 10095.5 7856.4 8977.6 8386.3 TRUE FALSE FALSE 9329.212745 10376.43724 10606.85127 9708.462049 12272.49246 9019.818239 10378.75256 10251.78019 7992.779741 8677.723301 1.075076079 1.195755716 1.222308075 1.118779859 1.414252567 1.039422199 1.196022528 1.181390537 0.921068749 1 13.08310087 -7.483840509 1.489353956 1.024485834 1.198188826 0.464487895 0.096009953 0.247102987 1.083468705 0.017219322 0.018660876 3.28E-08 7.483840509 0.173702991 DYLLS(ph)ESEDEGDNDGERK ddPTM_HeLa_Curcumin_4h_R1 1 DYLLSESEDEGDNDGERK 18 1 Q9BVJ6-3;Q9BVJ6 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 0 DYLLS(0.987)ES(0.013)EDEGDNDGERK 111.93 0.00030552 5762300 861.09 780.7 966.3 1053.1 1247.6 1192.6 692.79 1006.8 1058.7 741.32 TRUE FALSE FALSE 792.9338179 848.1802293 1002.111928 1048.742551 1232.723185 945.2413166 712.2278229 1313.768685 942.5632587 767.0808148 1.033703102 1.105724733 1.306396808 1.367186522 1.607031699 1.232257799 0.928491248 1.712686147 1.228766566 1 9.583234769 -6.834782228 2.379994602 1.016057152 1.350983039 0.265681549 0.208612492 0.220813297 2.559595057 0.031710502 0.043798247 1.46E-07 6.834782228 0.334925887 DYLLSES(ph)EDEGDNDGERK ddPTM_HeLa_Curcumin_4h_R1 1 DYLLSESEDEGDNDGERK 18 1 Q9BVJ6-3;Q9BVJ6 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 0 DYLLS(0.434)ES(0.566)EDEGDNDGERK 121.47 0.00015603 5911200 1653.8 1487.2 1571.1 1635.9 1664.2 1587 1314.3 1280.8 1620.7 1240.1 TRUE FALSE FALSE 1522.899985 1615.746941 1629.326348 1629.131079 1644.355502 1257.838311 1351.175721 1671.310024 1442.913265 1283.193383 1.186804737 1.259160905 1.269743415 1.269591241 1.281455721 0.980240646 1.052979028 1.302461536 1.124470625 1 10.32552289 -8.937878403 0.857135365 1.004710301 1.195798043 0.17779741 0.106778001 0.54379547 0.756665406 0.061282147 0.02149629 1.15E-09 8.937878403 0.191087742 DYNASASTISPPS(ph)SMEEDKFSR ddPTM_HeLa_Curcumin_4h_R1 1 DYNASASTISPPSSMEEDKFSR 22 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 DYNASASTIS(0.012)PPS(0.486)S(0.486)MEEDKFS(0.015)R 68.189 0.0064284 41453000 2805.3 2987.7 2803.3 3078.3 3268.6 1792.3 2186 3069.7 2643.1 2723.6 TRUE FALSE FALSE 2583.257545 3245.943475 2907.192764 3065.56281 3229.62408 1420.556777 2247.333277 4005.637399 2353.158543 2818.244897 0.916619257 1.151760615 1.03156144 1.087756005 1.145969991 0.504057251 0.797422991 1.421323393 0.834973052 1 11.46058127 -4.248166802 24.0075318 0.959597282 1.421323923 0.371372804 0.186035743 1076.267027 1946700.205 0.025087982 0.610877689 5.65E-05 4.248166802 0.46172664 DYNPYNYSDSIS(ph)PFNK ddPTM_HeLa_Curcumin_4h_R1 2 DYNPYNYSDSISPFNK 16 0 E3W994;J3KR49;O75122;E7ERI8;E7EW49;O75122-3;A0A0U1RQI6;H7C4X8;H7C5M8 E3W994 CLASP2 CLIP-associating protein 2 1 0 DYNPYNYS(0.001)DS(0.028)IS(0.971)PFNK;DYNPYNYSDSIS(1)PFNK ; 320 3.44E-112 19822200 7878.3 7083.7 7162.4 6616.3 6919.4 10865.6 8197.2 6483.8 6980.8 6668.9 TRUE FALSE FALSE 7254.724242 7695.983464 7427.844845 6588.923504 6836.890674 8611.952079 8427.19137 8460.680772 6215.023705 6900.643779 1.051311222 1.115255868 1.076398823 0.954827363 0.990761282 1.247992558 1.221218141 1.226071225 0.900644042 1 12.75251525 -5.257907343 24.9543477 1.028496423 1.230706404 0.740108731 0.058959337 98.53141328 696134.7364 0.006788627 0.01659215 5.52E-06 5.257907343 0.202209981 DYNVTANSK ddPTM_HeLa_Curcumin_4h_R1 2 DYNVTANSK 9 0 P00338;P00338-3;P00338-5;P00338-2;F5GYU2;F5GXY2;F5GXH2 P00338 LDHA L-lactate dehydrogenase A chain 0 0 ; ; 185.6 9.82E-17 76058000 12445.3 8987.7 11317.1 11569.1 11215.5 12466.7 10242 10128.5 10527.2 10239.4 FALSE FALSE TRUE 11460.24137 9764.55674 11736.52168 11521.23013 11081.76249 9880.965891 10529.36296 13216.63302 9372.392498 10595.21839 1.081642771 0.921600328 1.107718713 1.087399024 1.045921102 0.932587279 0.99378442 1.247414875 0.884587005 1 13.3711257 -1.801880875 0.005929457 5.44E-08 2.165727771 0.102482869 0.096669301 88106.19535 46.69543771 7902.576352 9198.864553 0.015780441 1.801880875 2.165727716 TGEK(ac)AAPR ddPTM_HeLa_Curcumin_4h_R1 1 TGEKAAPR 8 1 Q8NEZ4;Q8NEZ4-3;H0Y765;H7BY37;Q8NEZ4-2 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 0 1 TGEK(1)AAPR 95.358 0.017351 2449600 1271.9 1181.8 1673 1073.7 1010.4 1246.8 535.48 227.17 1468.2 1112 FALSE TRUE FALSE 1171.227773 1283.949526 1735.002852 1069.257314 998.3516399 988.1996257 550.5041276 296.4330872 1307.142133 1150.641917 1.017890758 1.115854991 1.507856463 0.92927026 0.86764755 0.858824636 0.478432186 0.257624099 1.136011224 1 10.16822322 -4.646338078 1.145675169 1.049499182 0.114120476 0.764105252 0.160114047 0.356030939 0.579280288 0.025113572 0.337085796 2.26E-05 4.646338078 -0.935378706 down DYPDFS(ph)PSVDAEAIQK ddPTM_HeLa_Curcumin_4h_R1 1 DYPDFSPSVDAEAIQK 16 0 P12429;D6RFG5;D6RCA8;D6RAZ8 P12429 ANXA3 Annexin A3;Annexin 1 0 DYPDFS(0.986)PS(0.014)VDAEAIQK 127.07 0.00050142 7312700 1706.5 1721 1521 1915.7 1491.5 2149.4 1701.9 1576 2030 1588.3 TRUE FALSE FALSE 1571.428724 1869.755571 1577.369598 1907.773341 1473.714837 1703.590211 1749.650734 2056.515145 1807.314079 1643.493307 0.956151581 1.137671546 0.959766366 1.16080384 0.896696586 1.036566565 1.064592552 1.251307283 1.099678393 1 10.68254987 -4.160195294 1.663611886 0.998324754 1.38835075 0.33258154 0.08407175 0.796907936 1.72733618 0.010523011 0.535420263 6.92E-05 4.160195294 0.390025997 DYQDNK(ac)ADVILK ddPTM_HeLa_Curcumin_4h_R1 1 DYQDNKADVILK 12 1 X6RAC9;P47813;O14602 X6RAC9 EIF1AX;EIF1AY "Eukaryotic translation initiation factor 1A, X-chromosomal;Eukaryotic translation initiation factor 1A, Y-chromosomal" 0 1 DYQDNK(1)ADVILK 118.61 0.0011697 1660800 621.59 573.81 449.31 649.39 683.21 380.99 439.14 475.02 949.15 597.03 FALSE TRUE FALSE 572.3904956 623.4075796 465.9618239 646.7029962 675.063167 301.9683794 451.4610865 619.8514113 845.0306197 617.7767481 0.926532922 1.00911467 0.754256008 1.046823142 1.092729969 0.488798551 0.730783552 1.003358273 1.3678576 1 9.270941761 -5.282888415 24.99069865 0.965318417 0.739960399 0.284182154 0.191476394 624.6840359 727831.0058 0.019526987 0.043701165 5.21E-06 5.282888415 -0.225358018 DYQDNKADVILK ddPTM_HeLa_Curcumin_4h_R1 1 DYQDNKADVILK 12 1 X6RAC9;P47813;O14602 X6RAC9 EIF1AX;EIF1AY "Eukaryotic translation initiation factor 1A, X-chromosomal;Eukaryotic translation initiation factor 1A, Y-chromosomal" 0 0 86.114 0.0075706 0 896.6 815.33 1001.6 953.17 636.36 1372.8 1172 933.27 1008.5 803.15 FALSE FALSE TRUE 825.6331639 885.8034922 1038.720177 949.2260351 628.7718226 1088.065805 1204.883166 1217.819727 897.8700731 831.0594027 0.993470697 1.065872655 1.249874767 1.142187949 0.756590709 1.309251543 1.449815936 1.465382285 1.080392172 1 9.698807792 -5.050110327 6.340424172 1.018796691 1.440699866 0.668524945 0.120552467 0.083691063 8.124981643 0.016925854 0.044658399 8.91E-06 5.050110327 0.421903174 DYQGPLKEHEVTIFVR ddPTM_HeLa_Curcumin_4h_R1 2 DYQGPLKEHEVTIFVR 16 1 P53396;P53396-2;P53396-3;K7EIE7 P53396 ACLY ATP-citrate synthase 0 0 ; ; 80.387 0.0057063 67529000 11374.1 10058.5 10401.8 10543.4 9428.3 12160.9 9493.9 9545.5 11847.1 10440.8 FALSE FALSE TRUE 10473.82798 10927.91192 10787.29986 10499.7742 9315.87368 9638.592258 9760.273282 12455.87901 10547.50277 10803.61702 0.969474201 1.011504934 0.998489657 0.971875825 0.862292106 0.892163452 0.903426442 1.152936001 0.976293657 1 13.39922678 -5.989249387 24.95506785 0.988312827 0.941388244 0.046474752 0.074933448 436.9370202 1014241.169 0.010559891 0.019128238 1.03E-06 5.989249387 -0.046924582 DYQYS(ph)DQGIDY ddPTM_HeLa_Curcumin_4h_R1 1 DYQYSDQGIDY 11 0 Q15417-3;Q15417-2;Q15417 Q15417-3 CNN3 Calponin-3 1 0 DYQYS(0.757)DQGIDY(0.243) 122.46 0.003879 28284000 6560.5 6337.3 6039.8 7276.4 7688.9 8065.1 6282.2 2473 6487.7 5720.5 TRUE FALSE FALSE 6041.229502 6885.067974 6263.640301 7246.292185 7597.214889 6392.307348 6458.461624 3227.006316 5776.015541 5919.286949 1.020600886 1.163158339 1.058174803 1.224183292 1.283467917 1.07991172 1.091087775 0.545168082 0.975795833 1 12.53120768 -4.259661619 24.87389926 1.064661063 0.545167896 0.730487403 0.099003994 68.90596894 964025.243 0.015604322 0.134224843 5.50E-05 4.259661619 -0.519493167 DYS(ph)PSRNPPEVEAR ddPTM_HeLa_Curcumin_4h_R1 2 DYSPSRNPPEVEAR 14 1 A0A3B3IRR3;Q9HCM7 A0A3B3IRR3 FBRSL1 Fibrosin-1-like protein 1 0 DY(0.006)S(0.974)PS(0.021)RNPPEVEAR;DY(0.026)S(0.892)PS(0.082)RNPPEVEAR ; 84.41 0.0065906 95891000 6089.9 4741 4884.1 5358.9 4630.9 5973 4231.9 2232.16 5959.7 4796.8 TRUE FALSE FALSE 5607.877989 5150.790915 5065.109042 5336.726292 4575.679542 4734.13247 4350.635724 2912.735308 5305.93582 4963.488443 1.129825939 1.037736055 1.020473625 1.075196679 0.921867673 0.953791376 0.876527824 0.586832294 1.068993286 1 12.27713872 -3.802456087 0.756945105 1.057252728 2.48E-19 0.892301089 0.04783904 1.277852091 0.323982808 0.009620942 1.345507741 0.000157596 3.802456087 -1.057252728 DYTGCSTSESLS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 1 DYTGCSTSESLSPVK 15 0 O95297-4;O95297-2;O95297 O95297-4 MPZL1 Myelin protein zero-like protein 1 1 0 DYTGCS(0.001)T(0.009)S(0.217)ES(0.067)LS(0.705)PVK 123.63 0.0010504 16535000 1600.1 1637.7 1843.7 2195.2 2005.2 2409.4 900.65 635.35 2451.6 1781.8 TRUE FALSE FALSE 1473.450397 1779.255491 1912.029144 2186.116844 1981.2893 1909.66328 925.919815 829.0652902 2182.665614 1843.717417 0.79917366 0.965036981 1.037051083 1.185711446 1.074616577 1.03576788 0.502202673 0.449670477 1.183839559 1 10.84840184 -4.753429907 24.32294943 0.956108822 0.475936104 0.738427494 0.126306999 54.96473479 166909.3642 0.018739473 0.0675688 1.76E-05 4.753429907 -0.480172718 DYTYEELLNR ddPTM_HeLa_Curcumin_4h_R1 2 DYTYEELLNR 10 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 0 0 ; ; 186.41 0.0015333 58597700 3880.39 3127.1 3442.24 3931.82 3707.33 4450.1 3345.42 3422.07 4286.13 3173.54 FALSE FALSE TRUE 3573.253037 3397.39259 3569.812443 3915.551171 3663.122511 3527.099097 3439.283481 4465.44339 3815.952262 3283.820279 1.088139037 1.034585422 1.087091296 1.192376817 1.115506392 1.074084084 1.047342178 1.359831845 1.162046622 1 11.68115946 -1 0.182743063 1.007907462 1.893675608 0.214883324 0.086624177 43.30744041 0.474171929 0.090387557 10.76518051 0.1 1 0.885768146 EAAAALVEEETRR ddPTM_HeLa_Curcumin_4h_R1 1 EAAAALVEEETRR 13 1 O75934 O75934 BCAS2 Pre-mRNA-splicing factor SPF27 0 0 130.15 0.002406 1877400 1776.5 1584.4 1648 1760.8 1587.8 2076.9 1558.1 1455.8 1916.5 1586.4 FALSE FALSE TRUE 1635.88815 1721.348476 1709.07633 1753.514276 1568.866522 1646.127529 1601.816093 1899.666718 1706.264745 1641.527282 0.996564704 1.048626176 1.041150122 1.06822122 0.95573588 1.002802419 0.975808389 1.157255648 1.039437336 1 10.68082301 -4.254501799 24.84558856 1.005528885 1.157255725 0.602524006 0.0341868 359.0668752 1285890.781 0.004524146 0.06128824 5.57E-05 4.254501799 0.15172684 EAAAQEAGADTPGKGEPPAPKS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 2 EAAAQEAGADTPGKGEPPAPKSPPK 25 2 O95466;O95466-2;O95466-3;K7EK60;K7ERL1;K7EJE6 O95466 FMNL1 Formin-like protein 1 1 0 EAAAQEAGADT(0.014)PGKGEPPAPKS(0.986)PPK;EAAAQEAGADT(0.008)PGKGEPPAPKS(0.992)PPK ; 87.61 1.71E-05 20299300 5044.4 4126.5 4800.7 5116 5229.8 4655.8 3714.1 3805.6 4715.9 4313.6 TRUE FALSE FALSE 4645.130417 4483.176273 4978.618165 5094.831348 5167.438051 3690.134598 3818.30765 4965.909921 4198.577569 4463.497279 1.04069301 1.004408873 1.115407461 1.141443812 1.157710586 0.82673616 0.855451995 1.112560311 0.940647503 1 12.12395883 -5.256388788 24.95872508 1.043281663 0.923969748 0.256570395 0.095693393 447.0222213 2209060.378 0.013032824 0.032150926 5.54E-06 5.256388788 -0.119311915 EAADLDAVPMS(ph)LS(ph)YEELVR ddPTM_HeLa_Curcumin_4h_R1 1 EAADLDAVPMSLSYEELVR 19 0 A0A0A6YYG7;Q6IBW4-2;Q6IBW4;Q6IBW4-4;H0YC55 A0A0A6YYG7 NCAPH2 Condensin-2 complex subunit H2 2 0 EAADLDAVPMS(0.717)LS(0.675)Y(0.608)EELVR 78.548 0.0040826 0 912.27 900 963.49 707.33 945.64 1038.7 792.14 981.9 978.74 1204.4 TRUE FALSE FALSE 840.0628669 977.7919897 999.197787 704.4032559 934.3638606 823.2619114 814.3653165 1281.27679 871.3746707 1246.25281 0.674070991 0.784585585 0.801761712 0.565216985 0.749738619 0.660589813 0.653451137 1.028103431 0.699195752 1 10.28338104 -9.343774885 0.890245817 1.013126969 0.727929931 0 0.149570322 0.485134318 0.636585534 0.096073073 0.021018364 4.53E-10 9.343774885 -0.285197038 EAADLDAVPMS(ph)LSYEELVR ddPTM_HeLa_Curcumin_4h_R1 1 EAADLDAVPMSLSYEELVR 19 0 A0A0A6YYG7;Q6IBW4-2;Q6IBW4;Q6IBW4-4;H0YC55 A0A0A6YYG7 NCAPH2 Condensin-2 complex subunit H2 1 0 EAADLDAVPMS(0.585)LS(0.263)Y(0.152)EELVR 105.02 0.00067918 4828400 1695.2 1136 1172.7 1470.3 1745.7 2486.2 1785.2 1047.1 1346 1326.6 TRUE FALSE FALSE 1561.023131 1234.190778 1216.161294 1464.216288 1724.883668 1970.534095 1835.287907 1366.35597 1198.347168 1372.699251 1.137192382 0.899097728 0.885963398 1.066669401 1.256563421 1.435517717 1.336991993 0.995378972 0.872985956 1 10.42279986 -5.771335005 4.888338865 1.036884293 1.276755876 0.466771021 0.137217589 0.140106583 8.808750352 0.019796449 0.038185571 1.69E-06 5.771335005 0.239871583 EAADLDAVPMSLS(ph)YEELVRR ddPTM_HeLa_Curcumin_4h_R1 2 EAADLDAVPMSLSYEELVRR 20 1 A0A0A6YYG7;Q6IBW4-2;Q6IBW4;Q6IBW4-4;H0YC55 A0A0A6YYG7 NCAPH2 Condensin-2 complex subunit H2 1 0 EAADLDAVPMS(0.036)LS(0.957)Y(0.007)EELVRR;EAADLDAVPMS(0.003)LS(0.993)Y(0.004)EELVRR ; 103.92 0.00023569 10023100 3946 3162.7 3161 3418.4 2597.25 5300.9 3622.7 2092.73 4341.5 3146.66 TRUE FALSE FALSE 3633.669936 3436.069695 3278.149441 3404.255567 2566.27949 4201.433587 3724.343212 2730.793743 3865.248312 3256.006201 1.11598987 1.055301951 1.006800736 1.045531045 0.788167876 1.290364123 1.143837874 0.83869427 1.187113314 1 11.66888773 -6.845109968 10.71516046 1.056374889 1.027652618 0.034359327 0.141475874 2.468214727 299.8102807 0.021745566 0.02859104 1.43E-07 6.845109968 -0.028722271 EAAEGLGSHDR ddPTM_HeLa_Curcumin_4h_R1 2 EAAEGLGSHDR 11 0 P17655 P17655 CAPN2 Calpain-2 catalytic subunit 0 0 ; ; 127.52 0.0010676 0 4108.5 3926.3 4191.2 4137.2 4066.2 4749.9 3444 3127.7 4786.8 3769.8 FALSE FALSE TRUE 3783.30789 4265.671877 4346.529559 4120.081363 4017.713221 3764.717198 3540.629371 4081.321332 4261.700016 3900.800269 0.969879929 1.093537629 1.114266114 1.056214386 1.02997153 0.965114063 0.907667434 1.046277956 1.092519412 1 11.92955442 -3.91592381 20.98798153 1.00276131 3.578321046 0 0.066239548 2422.008394 586652.4847 0.008876017 8801.572048 0.00012136 3.91592381 2.575559735 EAAENSLVAYK ddPTM_HeLa_Curcumin_4h_R1 2 EAAENSLVAYK 11 0 P62258;P62258-2;K7EM20 P62258 YWHAE 14-3-3 protein epsilon 0 0 ; ; 190.57 4.19E-16 33677000 10501.8 7959.7 8841 9130.1 8796.6 10395.9 9279.7 9497.9 10089.8 8532 FALSE FALSE TRUE 9670.571449 8647.701 9168.655237 9092.322065 8691.70629 8239.673154 9540.063407 12393.76599 8982.974183 8828.486365 1.095382725 0.979522496 1.038530826 1.029884591 0.984506962 0.933305304 1.080600118 1.403838152 1.017498789 1 13.1079504 -4.276426878 3.932194042 1.028801194 1.433690459 0.875522295 0.043891843 0.067500248 2.108122054 0.00725154 0.076101072 5.29E-05 4.276426878 0.404889265 EAAEPLSEPKEDQEAAELLS(ph)EPEEESER ddPTM_HeLa_Curcumin_4h_R1 2 EAAEPLSEPKEDQEAAELLSEPEEESER 28 1 A0A0A0MTR7;A0A0A0MTC1;Q63HN8;Q63HN8-4 A0A0A0MTR7 RNF213 E3 ubiquitin-protein ligase RNF213 1 0 EAAEPLSEPKEDQEAAELLS(1)EPEEESER;EAAEPLSEPKEDQEAAELLS(1)EPEEESER ; 171.93 1.09E-14 63027000 3557 3750.8 4095.6 3985.5 4179.4 4058.9 3162 1480.98 3233.1 3708 TRUE FALSE FALSE 3275.459697 4075.002439 4247.386539 3969.009057 4129.563385 3217.038387 3250.71721 1932.523984 2878.437019 3836.852724 0.853683978 1.062069027 1.106997543 1.034443942 1.076289261 0.838457616 0.847235337 0.503674267 0.750207846 1 11.90570767 -4.063073771 1.365357915 0.966943809 0.129444083 0.628193357 0.108386735 0.951565146 1.096579961 0.014925389 1.24365377 8.65E-05 4.063073771 -0.837499725 EAAEQDVEK ddPTM_HeLa_Curcumin_4h_R1 2 EAAEQDVEK 9 0 P26373;P26373-2;J3KS98 P26373 RPL13 60S ribosomal protein L13 0 0 ; ; 156.83 4.62E-08 9387700 6433.2 5689.3 6732.7 5910.2 6355.6 8000.8 5957.2 5508.1 6316.7 6077.6 FALSE FALSE TRUE 5924.005432 6181.057741 6982.219785 5885.745158 6279.813621 6341.343892 6124.342999 7187.494334 5623.773814 6288.796148 0.941993554 0.982868199 1.110263335 0.935909675 0.998571662 1.008355772 0.97384982 1.142904646 0.89425284 1 12.61856816 -4.259238266 24.41409818 0.983688465 1.142904723 0.440714194 0.054069152 91.39666436 1013646.073 0.006496745 0.057433077 5.51E-05 4.259238266 0.159216258 EAAFS(ph)PGQQDWSR ddPTM_HeLa_Curcumin_4h_R1 2 EAAFSPGQQDWSR 13 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 EAAFS(1)PGQQDWSR;EAAFS(1)PGQQDWSR ; 244.57 4.15E-27 104085000 6348.6 4769.1 5423.7 5844.2 5728.6 6823.5 5071.4 4435.9 6019 4240.3 TRUE FALSE FALSE 5846.101611 5181.319753 5624.707093 5820.018249 5660.290186 5408.229183 5213.689835 5788.38549 5358.730759 4387.650109 1.332399226 1.180887177 1.281940664 1.326454504 1.290050493 1.232602657 1.188264721 1.319245005 1.221321351 1 12.09923277 -9.367100366 0.930111867 0.988662709 1.270333496 0.216401816 0.084285044 0.222658013 0.32191806 0.044786613 0.009891211 4.29E-10 9.367100366 0.281670787 EAAGGNDS(ph)SGATSPINPAVALE ddPTM_HeLa_Curcumin_4h_R1 1 EAAGGNDSSGATSPINPAVALE 22 0 P32004-3;P32004-2;P32004;H3BLW5 P32004-3 L1CAM Neural cell adhesion molecule L1 1 0 EAAGGNDS(0.943)S(0.057)GATSPINPAVALE 117.6 8.69E-06 3269300 720.47 632.85 970.44 1116.9 998 1509.8 552.82 219.04 1000.3 778.95 TRUE FALSE FALSE 663.4440393 687.5507341 1006.40536 1112.278564 986.0995018 1196.650461 568.3306414 285.8242877 890.5695926 806.0184545 0.823112716 0.853021082 1.248613297 1.379966622 1.223420501 1.484643998 0.705108721 0.354612585 1.104899755 1 9.654669061 -2.612308812 10.89872019 0.975919759 1.01439228 0 0.327521541 0 0 0.044248868 0 0.002441694 2.612308812 0.038472521 EAAGPAPS(ph)PMR ddPTM_HeLa_Curcumin_4h_R1 2 EAAGPAPSPMR 11 0 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 0 EAAGPAPS(1)PMR;EAAGPAPS(1)PMR ; 126.5 0.003353 588450000 8232.4 6171 6894.1 7180.3 6668.3 9950.6 7405.7 2130.5 7998.1 6145.4 TRUE FALSE FALSE 7580.796853 6704.393743 7149.601411 7150.589821 6588.784878 7886.733394 7613.484011 2780.079642 7120.72844 6358.952193 1.192145596 1.054323659 1.124336399 1.124491835 1.036143169 1.240256752 1.197285933 0.437191468 1.119795876 1 12.63457335 -4.256673932 24.98842655 1.106144766 0.437191193 0.886927362 0.073072 141.7589245 743311.1266 0.012240723 0.132957271 5.54E-05 4.256673932 -0.668953573 AVS(ph)LDSPVSVGSSPPVK ddPTM_HeLa_Curcumin_4h_R1 1 AVSLDSPVSVGSSPPVK 17 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 0 AVS(0.465)LDS(0.445)PVS(0.038)VGS(0.052)SPPVK 155.26 0.00017829 27215000 6766.9 3873.4 6111.3 6403.4 5082.8 7246 7430.7 9473.1 4957.7 5459.9 TRUE FALSE FALSE 6231.292725 4208.199436 6337.790154 6376.904427 5022.19093 5743.097921 7639.185443 12361.40458 4413.852714 5649.631119 1.102955679 0.744862691 1.121806012 1.128729344 0.888941388 1.016543877 1.352156501 2.18800207 0.781263877 1 12.46394096 -4.282319599 2.22049672 1.025458202 2.458049267 0.878050747 0.136474011 0.122000628 0.706210322 0.015755978 0.336235314 5.22E-05 4.282319599 1.432591065 up EAALPPVS(ph)PLKAALSEEELEK ddPTM_HeLa_Curcumin_4h_R1 2 EAALPPVSPLKAALSEEELEK 21 1 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 0 EAALPPVS(0.996)PLKAALS(0.004)EEELEK;EAALPPVS(1)PLKAALSEEELEK ; 102.59 3.86E-05 126612000 12441.8 9829 9835.3 10397.3 8629.3 13405.8 10386.3 12147.7 12425.5 11221.1 TRUE FALSE FALSE 11457.0184 10678.57496 10199.80487 10354.27873 8526.401233 10625.28597 10677.71162 15851.47781 11062.45374 11611.03239 0.986735547 0.919692117 0.87845805 0.891762109 0.734336185 0.915102603 0.919617762 1.365208302 0.952753671 1 13.50320863 -4.259061407 24.84765681 0.947958287 1.365208461 0.74120725 0.077807051 96.39815775 1007202.514 0.012895903 0.115307051 5.51E-05 4.259061407 0.417250174 EAALPPVS(ph)PLKAALSEEELEKK ddPTM_HeLa_Curcumin_4h_R1 3 EAALPPVSPLKAALSEEELEKK 22 2 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 0 EAALPPVS(1)PLKAALSEEELEKK;EAALPPVS(0.972)PLKAALS(0.028)EEELEKK;EAALPPVS(0.999)PLKAALS(0.001)EEELEKK ;; 91.725 0.00021107 1397140000 8345.9 7124.6 7003.8 7534.1 5692.5 9195.7 7418.6 8452.7 8810.5 7997.3 TRUE FALSE FALSE 7685.313208 7740.418677 7263.366989 7502.92589 5624.620655 7288.408163 7626.74595 11029.88932 7844.010193 8275.20558 0.928715684 0.93537479 0.877726471 0.906675468 0.67969558 0.880752519 0.921638245 1.332884025 0.947893091 1 13.01457944 -4.261005369 25 0.926711602 1.332884147 0.693909702 0.084767207 18.26658819 1051855.899 0.013370366 0.105139208 5.48E-05 4.261005369 0.406172545 EAALPPVSPLK ddPTM_HeLa_Curcumin_4h_R1 1 EAALPPVSPLK 11 0 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 0 101.38 0.0090834 722130 2329.6 2258.3 2266.9 2159 2153 2251 2039.8 1638.4 2611.3 2235.3 FALSE FALSE TRUE 2145.209702 2453.497389 2350.913308 2150.06663 2127.326881 1784.117226 2097.031298 2137.940618 2324.846923 2312.976509 0.927467138 1.060753268 1.016401723 0.929566998 0.919735619 0.771351209 0.906637525 0.924324397 1.005132095 1 11.1755349 -5.778494001 2.588306533 0.976455987 0.870238039 0.514287207 0.053242013 0.205155504 2.808518927 0.008498611 0.017608014 1.67E-06 5.778494001 -0.106217948 EAALSTALSEK ddPTM_HeLa_Curcumin_4h_R1 2 EAALSTALSEK 11 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 207.34 1.40E-22 10476200 6537.3 5369.3 6282.5 6794.4 7466.5 7490.6 6506 5785.5 5878.3 5455.4 FALSE FALSE TRUE 6019.865807 5833.398367 6515.334977 6766.286573 7377.466864 5936.965124 6688.54085 7549.472317 5233.465197 5644.974744 1.066411469 1.033379002 1.154183193 1.198638945 1.306908746 1.051725719 1.184866391 1.33737929 0.927101614 1 12.46275141 -6.635669276 2.439802975 1.031249541 1.209861873 0.595311477 0.080474472 0.159735033 1.936583035 0.012011681 0.017742021 2.31E-07 6.635669276 0.178612331 EAALSTALSEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 EAALSTALSEKR 12 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 1 ; EAALSTALSEK(1)R;EAALSTALSEK(1)R 267.39 3.68E-161 0 2142.1 2540.5 1849.14 1831.33 2669.3 4112.9 2991.5 2648.1 4716.7 2180.1 FALSE TRUE FALSE 1972.550525 2760.0895 1917.670755 1823.752442 2637.470341 3259.838178 3075.433439 3455.4935 4199.289811 2255.858313 0.874412419 1.22352077 0.850084752 0.80845168 1.169164892 1.445054488 1.363309664 1.531786584 1.861504239 1 11.13946074 -5.457773918 3.28718934 0.947312694 1.437475229 0.084028247 0.311014001 0.083537559 1.763548925 0.016824406 0.039397759 3.49E-06 5.457773918 0.490162534 EAALSTALSEKR ddPTM_HeLa_Curcumin_4h_R1 2 EAALSTALSEKR 12 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 126.71 0.00017656 21770000 7716.9 5564.1 6130.9 6419.7 5395.6 7823.6 5456.7 5826.6 7750.7 7616.2 FALSE FALSE TRUE 7106.099222 6045.036011 6358.116547 6393.136982 5331.260994 6200.89717 5609.800316 7603.103518 6900.467601 7880.862383 0.901690561 0.767052604 0.806779289 0.81122302 0.67648193 0.786829774 0.711825692 0.96475527 0.875598033 1 12.94413779 -7.664422199 0.912975296 0.978638201 0.778037363 0.330155633 0.081239409 0.248514044 0.435140584 0.018292205 0.017345481 2.17E-08 7.664422199 -0.200600839 EAANEAGDSS(ph)QDEAEDDVK ddPTM_HeLa_Curcumin_4h_R1 1 EAANEAGDSSQDEAEDDVK 19 0 A0A0C4DH01;Q9NVU0-3;Q9NVU0-2;Q9NVU0-5;Q9NVU0-4;Q9NVU0 A0A0C4DH01 POLR3E DNA-directed RNA polymerase III subunit RPC5 1 0 EAANEAGDS(0.043)S(0.957)QDEAEDDVK 203.06 2.36E-13 11668000 2175.2 1843.5 1686.6 2048.2 2169.4 2048.6 1666.6 1886 1917.2 1837.3 TRUE FALSE FALSE 2003.030625 2002.843926 1749.10688 2039.725091 2143.531322 1623.697268 1713.360311 2461.032718 1706.887957 1901.146038 1.053591142 1.053492938 0.920027628 1.072892377 1.1274943 0.854062358 0.901224985 1.294499564 0.897820537 1 10.89265364 -9.690989821 1.587949744 1.000093421 1.030002554 0.038202336 0.123607137 2.588269714 11.82138188 0.079615843 0.017893445 2.04E-10 9.690989821 0.029909132 EAARS(ph)PDKPGGS(ph)PSASR ddPTM_HeLa_Curcumin_4h_R1 2 EAARSPDKPGGSPSASR 17 2 Q9Y3T9 Q9Y3T9 NOC2L Nucleolar complex protein 2 homolog 2 0 EAARS(1)PDKPGGS(0.872)PS(0.111)AS(0.017)R;EAARS(1)PDKPGGS(0.847)PS(0.135)AS(0.018)R ; 75.868 0.0096179 353574000 12144.5 10243 10584.2 11075.5 10356 12628.2 9656.9 4894.4 11773.7 10502.3 TRUE FALSE FALSE 11183.25001 11128.35928 10976.45976 11029.67252 10232.51146 10008.96897 9927.846624 6386.680029 10482.15457 10867.25414 1.029077802 1.024026781 1.010049054 1.014945668 0.941591255 0.921020972 0.913556129 0.587699519 0.964563304 1 13.40769984 -3.819323833 1.02193494 1.011072283 3.71E-13 0.927466881 0.033518765 0.634742698 0.279283323 0.004586554 0.87019511 0.000151592 3.819323833 -1.011072283 EAAS(ph)QRPLS(ph)SSASNR ddPTM_HeLa_Curcumin_4h_R1 3 EAASQRPLSSSASNR 15 1 A0A087X2H1;Q9ULT8;H0YJP0 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 2 0 EAAS(1)QRPLS(0.991)S(0.009)SASNR;EAAS(1)QRPLS(0.96)S(0.039)SASNR;EAAS(1)QRPLS(0.555)S(0.401)S(0.041)AS(0.003)NR ;; 113.65 0.0073636 106544000 848.58 547.07 696.649 715.142 745.27 1019.46 470.55 620.63 674.568 633.34 TRUE FALSE FALSE 781.4139976 594.3562931 722.4674248 712.1829319 736.383142 808.0125043 483.7523666 809.85723 600.5695781 655.3485179 1.192364027 0.90693162 1.102417119 1.086723953 1.12365119 1.232950838 0.738160465 1.235765715 0.916412507 1 9.356118533 -4.841585133 23.62405183 1.090004188 0.986296867 0.033647138 0.150920635 32.55417887 9591.831032 0.018678028 0.05603417 1.44E-05 4.841585133 -0.103707322 EAAS(ph)SPAGEPLR ddPTM_HeLa_Curcumin_4h_R1 1 EAASSPAGEPLR 12 0 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 0 EAAS(0.5)S(0.5)PAGEPLR 183.06 6.73E-05 65082000 7089.4 6884.6 6851.5 6669.9 7552.8 6687.4 6277.7 4605 6643.2 5490.5 TRUE FALSE FALSE 6528.266509 7479.674147 7105.422617 6642.301721 7462.737793 5300.357857 6453.835366 6009.043301 5914.45758 5681.294466 1.149080821 1.316544001 1.25066966 1.169152868 1.313562928 0.932948976 1.135979732 1.057689112 1.041040491 1 12.47200397 -8.780719541 0.985226611 1.012001261 1.166620589 0.21445982 0.109778799 0.54377557 1.048767323 0.047983125 0.021948974 1.66E-09 8.780719541 0.154619328 EAASGTT(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 1 EAASGTTPQK 10 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 EAAS(0.03)GT(0.299)T(0.671)PQK 116.74 0.014877 15473000 6281 19036 5055.1 5381.2 5051.8 3589.3 3817.1 1029.1 3712.2 3935.8 TRUE FALSE FALSE 5783.852222 20681.38702 5242.446453 5358.93402 4991.560584 2844.83872 3924.197553 1342.867853 3304.980947 4072.568757 1.420197563 5.078216784 1.287257936 1.315860907 1.225654098 0.698536695 0.963568152 0.329734851 0.811522443 1 11.99172334 -5.438499706 1.701685969 1.546482065 0.648778384 0.143986494 1.167102638 0.768749471 4.309709318 0.184770615 0.544292739 3.64E-06 5.438499706 -0.897703681 EAASS(ph)PAGEPLR ddPTM_HeLa_Curcumin_4h_R1 3 EAASSPAGEPLR 12 0 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 0 EAAS(0.084)S(0.916)PAGEPLR;EAAS(0.41)S(0.59)PAGEPLR;EAAS(0.033)S(0.967)PAGEPLR ;; 176.99 0.00013512 73596200 9259.1 8239.3 8627.2 8403.2 9808.3 8910.1 7357.1 4682.1 7794.3 7513.2 TRUE FALSE FALSE 8526.232465 8951.468378 8946.931621 8368.429785 9691.342429 7062.044822 7563.520425 6109.650736 6939.28479 7774.283141 1.096722657 1.151420422 1.150836863 1.076424621 1.246589847 0.908385339 0.972889756 0.785879627 0.892594811 1 12.92449394 -5.062664051 17.38498367 1.076863028 0.894695586 0.456048018 0.099020536 6.02763662 1672.052445 0.012349481 0.031487261 8.66E-06 5.062664051 -0.182167442 EAASSSSGTQPAPPAPAS(ph)PWDSKK ddPTM_HeLa_Curcumin_4h_R1 2 EAASSSSGTQPAPPAPASPWDSKK 24 1 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 1 0 EAASSSSGTQPAPPAPAS(0.978)PWDS(0.022)KK;EAASSSSGTQPAPPAPAS(0.994)PWDS(0.006)KK ; 135.03 9.74E-07 184402000 7721.6 5974.2 6531.9 6396.2 6778.7 7910.4 7322.5 2688.3 7481.3 6197.4 TRUE FALSE FALSE 7110.427212 6490.583227 6773.97796 6369.734219 6697.86843 6269.693871 7527.949642 3507.950295 6660.620107 6412.759189 1.108793735 1.012135812 1.056328136 0.993290724 1.044459683 0.977690521 1.173901814 0.547026668 1.038651213 1 12.64672952 -4.252416672 24.99916318 1.04692687 0.547026409 0.877358297 0.055853542 301.7442867 836023.563 0.007913623 0.13026923 5.59E-05 4.252416672 -0.49990046 EAATQEDPEQLPELEAHGVS(ph)ES(ph)EGEERPVAEEEILLR ddPTM_HeLa_Curcumin_4h_R1 2 EAATQEDPEQLPELEAHGVSESEGEERPVAEEEILLR 37 1 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2;X6RJY0 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 2 0 EAAT(0.001)QEDPEQLPELEAHGVS(1)ES(1)EGEERPVAEEEILLR;EAATQEDPEQLPELEAHGVS(1)ES(1)EGEERPVAEEEILLR ; 92.349 8.59E-12 17255100 1851.92 1589.15 1733.4 1875.85 1570.94 2524.5 2095.7 1363.47 1972.23 1769.05 TRUE FALSE FALSE 1705.338578 1726.509045 1797.641329 1868.08823 1552.207567 2000.890243 2154.499702 1779.185726 1755.881303 1830.524356 0.931612066 0.943177314 0.98203628 1.020520827 0.847957888 1.093069446 1.176984996 0.97195414 0.959223131 1 10.83804125 -5.211985948 24.77376647 0.963381309 1.09030121 0.440156118 0.064217583 226.8133279 113621.9736 0.0085307 0.021749062 6.14E-06 5.211985948 0.1269199 EAATQEDPEQLPELEAHGVS(ph)ESEGEERPVAEEEILLR ddPTM_HeLa_Curcumin_4h_R1 2 EAATQEDPEQLPELEAHGVSESEGEERPVAEEEILLR 37 1 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2;X6RJY0 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 0 EAATQEDPEQLPELEAHGVS(0.5)ES(0.5)EGEERPVAEEEILLR;EAATQEDPEQLPELEAHGVS(0.711)ES(0.289)EGEERPVAEEEILLR ; 69.803 2.20E-06 53118600 3563.82 2814.17 2540.02 2756.21 3253.2 3430.8 2764.4 2057.63 2869.91 2199.15 TRUE FALSE FALSE 3281.739886 3057.414315 2634.155376 2744.805533 3214.407715 2719.213407 2841.961624 2684.991915 2555.088053 2275.570299 1.442161505 1.34358157 1.157580312 1.206205554 1.412572363 1.194959087 1.248900825 1.179920443 1.122834155 1 11.15201244 -9.542728649 1.322316442 1.000802425 1.291859137 0.389529185 0.100523248 0.284934053 0.896318092 0.073478691 0.01766466 2.87E-10 9.542728649 0.291056711 EAAVSASDILQESAIHS(ph)PGTVEK ddPTM_HeLa_Curcumin_4h_R1 3 EAAVSASDILQESAIHSPGTVEK 23 0 F5H3K2;F5H8B7;E7ENF1;G5EA44;F5H7W8;Q96C57 F5H3K2 C12orf43 Uncharacterized protein C12orf43 1 0 EAAVSASDILQESAIHS(0.998)PGT(0.002)VEK;EAAVSASDILQES(0.123)AIHS(0.723)PGT(0.154)VEK;EAAVSASDILQESAIHS(0.975)PGT(0.025)VEK ;; 142.01 6.29E-06 209382000 7422.49 7025.33 5802.89 6489.79 8078.67 10754.1 7398.71 3817.08 8427.62 6716.46 TRUE FALSE FALSE 6834.992084 7632.568221 6017.950208 6462.936969 7982.337137 8523.578436 7606.29789 4980.89012 7503.131171 6949.856485 0.983472407 1.098233933 0.865909997 0.929938191 1.148561435 1.226439489 1.094453951 0.716689637 1.079609512 1 12.76276747 -5.77548556 24.9581568 0.98643529 1.062809096 0.028090082 0.139291024 508.1970827 902997.5141 0.019564628 0.035591381 1.68E-06 5.77548556 0.076373806 EAAYHPEVAPDVR ddPTM_HeLa_Curcumin_4h_R1 2 EAAYHPEVAPDVR 13 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 ; ; 102.33 0.0046662 23670700 7466.1 5544.5 6084.7 6404.1 6245.8 7902.6 5568.3 6078.4 7082.2 6700.1 FALSE FALSE TRUE 6875.150307 6023.741874 6310.204335 6377.601531 6171.322914 6263.511679 5724.531512 7931.676178 6305.300379 6932.927976 0.991666195 0.868859722 0.910178839 0.919900157 0.890146693 0.903443927 0.825701858 1.144058644 0.909471496 1 12.75924906 -7.350731261 8.17452549 0.996244363 0.916832626 0.016791595 0.084106751 0.372888471 31.095873 0.012334241 0.01407957 4.46E-08 7.350731261 -0.079411737 EADDDEEVDDNIPEMPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 EADDDEEVDDNIPEMPSPK 19 0 P26358;P26358-2;P26358-3 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 0 EADDDEEVDDNIPEMPS(1)PK;EADDDEEVDDNIPEMPS(1)PK;EADDDEEVDDNIPEMPS(1)PK ;; 193.63 2.29E-10 182629000 18584.7 17655 17301.4 20128.6 18012.9 20894 17812.5 14518.6 20946.5 18527.6 TRUE FALSE FALSE 17113.70138 19181.01953 17942.6051 20045.31319 17798.10793 16560.34888 18312.27081 18945.2543 18648.72136 19171.43272 0.892666794 1.000500057 0.935903193 1.045582429 0.928366085 0.863803406 0.955185305 0.988202321 0.972734883 1 14.22667054 EADDDEEVDDNIPEMPS(ph)PKK ddPTM_HeLa_Curcumin_4h_R1 6 EADDDEEVDDNIPEMPSPKK 20 1 P26358;P26358-2;P26358-3 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 0 EADDDEEVDDNIPEMPS(1)PKK;EADDDEEVDDNIPEMPS(1)PKK;EADDDEEVDDNIPEMPS(1)PKK;EADDDEEVDDNIPEMPS(1)PKK;EADDDEEVDDNIPEMPS(1)PKK;EADDDEEVDDNIPEMPS(1)PKK ;;;;; 154.31 8.24E-06 310338000 16548.8 13890.4 14159.5 16872.2 14200.1 17970.3 15864 11128.8 18022.5 16304.4 TRUE FALSE FALSE 15238.94502 15091.02428 14684.26353 16802.38731 14030.77308 14243.05721 16309.10114 14521.91989 16045.47684 16870.97669 0.903263949 0.894496185 0.870386096 0.995934475 0.831651501 0.844234301 0.966695731 0.860763438 0.951069825 1 14.04225588 -9.157105306 0.530551196 1.017828474 0.89337833 0.261048534 0.050924598 1.046921378 0.434057187 0.065937418 0.01204716 6.96E-10 9.157105306 -0.124450144 EADDIVNWLK ddPTM_HeLa_Curcumin_4h_R1 3 EADDIVNWLK 10 0 P07237;I3L312;I3L3P5 P07237 P4HB Protein disulfide-isomerase 0 0 ;; ;; 160.59 5.82E-09 42947530 5786.23 4746.63 4860.25 5599.98 5017.96 5464.06 4263.55 2974.12 5139.53 5097.42 FALSE FALSE TRUE 5328.24379 5156.907547 5040.375141 5576.808767 4958.124104 4330.752363 4383.173738 3880.915497 4575.736417 5274.554966 1.010178835 0.97769529 0.955601975 1.057304133 0.940008046 0.821064979 0.831003519 0.735780653 0.867511372 1 12.36483366 -5.285843261 2.197074214 1.002175928 0.786174649 0.687246509 0.053867699 0.067880094 0.631883649 0.004525587 0.013311804 5.18E-06 5.285843261 -0.216001278 VNVTVDYIRPAS(ph)PATETVPAFSER ddPTM_HeLa_Curcumin_4h_R1 1 VNVTVDYIRPASPATETVPAFSER 24 1 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 0 VNVT(0.005)VDY(0.016)IRPAS(0.485)PAT(0.185)ET(0.3)VPAFS(0.009)ER 52.849 0.0062854 65976000 1486 1436.5 1666.9 1268.5 1333.6 1387 1685.6 2557.7 1675 1150.8 TRUE FALSE FALSE 1368.381532 1560.664659 1728.67678 1263.251283 1317.697691 1099.320565 1732.893399 3337.530956 1491.256691 1190.790214 1.149137367 1.3106126 1.451705565 1.060851246 1.106574168 0.923185757 1.455246591 2.802786684 1.252325282 1 10.21770356 -4.281619116 2.972211641 1.110752191 3.043913908 0.910955946 0.153059415 0.073352295 0.958902349 0.022357503 0.327795839 5.23E-05 4.281619116 1.933161717 up EADESLNFEEQILEAAK ddPTM_HeLa_Curcumin_4h_R1 1 EADESLNFEEQILEAAK 17 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 187.63 8.95E-06 2881200 1495 1047 1297.7 1324.8 1571.1 1617.8 1084.5 1245.2 1481.2 1314.1 FALSE FALSE TRUE 1376.669172 1137.498015 1345.793904 1319.318329 1552.365659 1282.250044 1114.928151 1624.855748 1318.716066 1359.764877 1.012431778 0.836540224 0.989725449 0.970254748 1.141642709 0.942993943 0.819941866 1.194953462 0.969811831 1 10.4091415 EADGILK(ac)PLPK ddPTM_HeLa_Curcumin_4h_R1 2 EADGILKPLPK 11 1 P49588;P49588-2 P49588 AARS "Alanine--tRNA ligase, cytoplasmic" 0 1 ; EADGILK(1)PLPK;EADGILK(1)PLPK 129.89 0.00087587 1817900 1392.6 1748.01 1308.62 1419.24 2699 3029.5 2478.2 2214.6 3364.7 980.34 FALSE TRUE FALSE 1282.374241 1899.100195 1357.118608 1413.367561 2666.816188 2401.14755 2547.731622 2889.821345 2995.600828 1014.406742 1.264161788 1.872128917 1.337844626 1.393294723 2.628941703 2.367046128 2.511548392 2.848779711 2.953056899 1 9.986420524 -5.403592923 0.401516219 1.031450337 3.315354963 0.083277323 0.662096179 0.688957969 0.139376374 0.088774051 0.662267909 3.95E-06 5.403592923 2.283904626 EADGSET(ph)PEPFAAEAK ddPTM_HeLa_Curcumin_4h_R1 1 EADGSETPEPFAAEAK 16 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 0 EADGS(0.002)ET(0.998)PEPFAAEAK 226.39 3.20E-21 31932000 1624.6 867.35 1185 1412.3 1213.8 1673.9 1345.8 21788 0 1216.6 TRUE FALSE FALSE 1496.011196 942.3198692 1228.917142 1406.456277 1199.326228 1326.714271 1383.559526 28431.0609 0 1258.876759 1.188369858 0.748540206 0.976201311 1.117231108 0.952695503 1.053887334 1.099042869 22.58446721 0 1 10.29792134 -4.261438559 10.09117141 1.049709188 22.63400318 0.997090947 0.351238051 0.000927021 3.221991399 0.017464169 0.135358304 5.48E-05 4.261438559 21.58429399 EADLVFIS(ph)VNTPTK ddPTM_HeLa_Curcumin_4h_R1 1 EADLVFISVNTPTK 14 0 O60701;E7ER83;E7ETF4;E7EV97 O60701 UGDH UDP-glucose 6-dehydrogenase 1 0 EADLVFIS(0.494)VNT(0.494)PT(0.013)K 202.01 6.07E-09 7074700 5261.9 5167.6 5934.6 4435.8 6099.5 8626.1 6882 5389.1 4540.4 4098.5 TRUE FALSE FALSE 4845.415063 5614.264318 6154.541497 4417.445835 6026.767446 6836.949624 7075.090398 7032.211782 4042.32948 4240.92257 1.14253797 1.323830894 1.451227037 1.041623789 1.421098204 1.612137338 1.668290397 1.658179716 0.953172196 1 12.05016243 -1.563111738 0.173037867 0.926709893 3.83950433 0.776260176 0.12460067 15.73692977 0.198679625 0.183505285 11.5278054 0.027345651 1.563111738 2.912794436 EADLVFISVNT(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 1 EADLVFISVNTPTK 14 0 O60701;E7ER83;E7ETF4;E7EV97 O60701 UGDH UDP-glucose 6-dehydrogenase 1 0 EADLVFIS(0.008)VNT(0.992)PTK 144.88 0.0018653 6657500 6161.9 6132.3 6362.4 5811.4 7358.7 10185 7511.6 5931.7 5131.2 5056.8 TRUE FALSE FALSE 5674.179113 6662.348687 6598.196141 5787.353967 7270.952309 8072.516191 7722.35528 7740.248024 4568.320198 5232.523424 1.08440587 1.273257308 1.260996962 1.106034985 1.389568994 1.542757774 1.475837689 1.479257214 0.873062541 1 12.35329115 -5.859416926 0.385750611 1.000230693 1.630155213 0.817682394 0.091788944 0.568738242 0.133354551 0.03181273 0.143718827 1.38E-06 5.859416926 0.62992452 EADQPTTEPGMVLDSVEAGDT(ph)TPPTKR ddPTM_HeLa_Curcumin_4h_R1 1 EADQPTTEPGMVLDSVEAGDTTPPTKR 27 1 A0A0J9YVR0;A0A0J9YWV8 A0A0J9YVR0 1 0 EADQPTTEPGMVLDS(0.089)VEAGDT(0.688)T(0.198)PPT(0.025)KR 90.674 4.83E-06 11805000 1622.8 1210.1 1450.4 1498.2 1495.8 1733.8 1720.7 1457.6 1596.2 1157.2 TRUE FALSE FALSE 1494.353668 1314.695652 1504.1531 1492.000845 1477.963562 1374.190336 1768.978211 1902.01553 1421.100853 1197.412614 1.247985573 1.097947054 1.256169413 1.246020652 1.234297639 1.147633088 1.47733387 1.58843786 1.186809657 1 10.22570466 -1 0.249080542 1.075308864 3.999652395 0.678011675 0.092648805 22.13663561 0.275956465 0.058340047 27.41085255 0.1 1 2.92434353 EAEAAIYHLQLFEELR ddPTM_HeLa_Curcumin_4h_R1 2 EAEAAIYHLQLFEELR 16 0 P14618;P14618-3;B4DNK4 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 153.41 0.00026093 2164720 1064.54 1046.72 1077.76 794.82 1237.2 1519.12 1433.7 1287.56 1104.51 1223.6 FALSE FALSE TRUE 980.2805357 1137.193813 1117.702734 791.5312454 1222.447198 1204.037388 1473.925763 1680.131117 983.3480163 1266.120009 0.774239826 0.898172215 0.882777877 0.625162891 0.965506579 0.950966243 1.164128008 1.326991995 0.776662567 1 10.30619844 -4.620251426 1.630096764 0.874200593 1.360492487 0.709133703 0.102689692 0.267011819 1.07251312 0.016865798 0.164752713 2.40E-05 4.620251426 0.486291894 EAEAAIYHLQLFEELRR ddPTM_HeLa_Curcumin_4h_R1 9 EAEAAIYHLQLFEELRR 17 1 P14618;P14618-3;B4DNK4 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ;;;;;;;; ;;;;;;;; 180.3 2.32E-06 244239420 24476.59 21083.58 23433.24 21698.18 19930.31 40014.04 28031.69 23050.47 20946.08 18535.64 FALSE FALSE TRUE 22539.24207 22905.95071 24301.69649 21608.39868 19692.65407 31714.67705 28818.18378 30078.45219 18648.34743 19179.75211 1.175158153 1.194277725 1.267049561 1.126625545 1.026741845 1.653549893 1.502531608 1.568239882 0.972293454 1 14.22729645 -1 0.236666883 1.027815321 4.644298467 0.664375331 0.134819524 21.76894535 0.267342379 0.084644608 31.119008 0.1 1 3.616483146 EAEALLQSMGLTPESPIVPPPMS(ph)PSSK ddPTM_HeLa_Curcumin_4h_R1 2 EAEALLQSMGLTPESPIVPPPMSPSSK 27 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 0 EAEALLQSMGLTPESPIVPPPMS(0.632)PS(0.154)S(0.214)K;EAEALLQSMGLTPESPIVPPPMS(0.756)PS(0.122)S(0.122)K ; 101.81 4.16E-07 40221000 7437.6 5646.7 6349.9 7032.2 5668.6 8128 7062.5 9533.2 7687 7397.4 TRUE FALSE FALSE 6848.906112 6134.775587 6585.23288 7003.10262 5601.005647 6442.161179 7260.654742 12439.82879 6843.755332 7654.459099 0.894760299 0.801464285 0.860313289 0.914904963 0.731731083 0.841622 0.948552295 1.625174115 0.894087387 1 12.90208472 -4.262623329 4.926635199 0.907842228 1.661542157 0.895698782 0.076100706 0.047941657 3.497985539 0.012899916 0.122842746 5.46E-05 4.262623329 0.753699928 EAEEES(ph)S(ph)GGEEEDEDENIEVVYSK ddPTM_HeLa_Curcumin_4h_R1 1 EAEEESSGGEEEDEDENIEVVYSK 24 0 P55010 P55010 EIF5 Eukaryotic translation initiation factor 5 2 0 EAEEES(1)S(1)GGEEEDEDENIEVVYSK 68.516 0.002492 6663600 2859.8 1591.4 2180.1 2464.2 2399.3 2907.5 1790.2 2489.9 2596.5 1702.8 TRUE FALSE FALSE 2633.443812 1728.953525 2260.896424 2454.003793 2370.689915 2304.451726 1840.428194 3249.059048 2311.670446 1761.972173 1.494600115 0.981260403 1.283162389 1.392759676 1.34547523 1.30788202 1.044527389 1.843989989 1.311978975 1 10.78297542 -9.52867227 1.230644438 0.99632025 1.335792405 0.020900873 0.242741708 0.536077123 1.427913316 0.156188322 0.03568815 2.96E-10 9.52867227 0.339472156 EAEEGEDDRDS(ph)ANGEDDS ddPTM_HeLa_Curcumin_4h_R1 1 EAEEGEDDRDSANGEDDS 18 1 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;P07910-3;G3V2D6 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 0 EAEEGEDDRDS(0.998)ANGEDDS(0.002) 111.45 0.0064786 9861100 968.96 1122.4 1179.3 1039 1307.4 1247.8 1228.6 754.66 921.06 726.85 TRUE FALSE FALSE 892.2657936 1219.415255 1223.005895 1034.700893 1291.810109 988.9922144 1263.071209 984.75236 820.0220224 752.1079834 1.186353307 1.621330024 1.626104127 1.37573449 1.717585955 1.3149604 1.67937482 1.309323105 1.090298256 1 9.554796001 -7.4351003 3.100232981 1.075511289 1.524521091 0.655151145 0.14336327 0.103305828 1.850485725 0.024546198 0.027425783 3.67E-08 7.4351003 0.449009802 EAEEGEDDRDSANGEDDS(ph) ddPTM_HeLa_Curcumin_4h_R1 1 EAEEGEDDRDSANGEDDS 18 1 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;P07910-3;G3V2D6 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 0 EAEEGEDDRDS(0.434)ANGEDDS(0.566) 87.157 0.0053758 0 830.86 984.27 895.5 624 1134.6 797.45 898.92 813.71 933.02 853.66 TRUE FALSE FALSE 765.0965543 1069.345913 928.6880178 621.4180533 1121.070636 632.0498809 924.1412759 1061.806433 830.6700403 883.3246215 0.866155585 1.210592218 1.051355295 0.703499074 1.269149086 0.715535224 1.046207989 1.202056874 0.940390452 1 9.786799915 -4.405120452 4.344369372 0.95642962 1.192445386 0.134185227 0.174746246 0.294133312 8.417736728 0.022063132 0.143864227 3.93E-05 4.405120452 0.236015766 EAEEGPTGASESQDS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 EAEEGPTGASESQDSPR 17 0 H0Y507;Q5TCZ1-2;Q5TCZ1-3;Q5TCZ1 H0Y507 SH3PXD2A SH3 and PX domain-containing protein 2A 1 0 EAEEGPTGASESQDS(1)PR;EAEEGPTGAS(0.009)ES(0.007)QDS(0.984)PR;EAEEGPTGASESQDS(1)PR ;; 217.65 1.45E-15 34734400 3756.77 3353.04 3078.37 3721.78 3224.97 4999.3 3706.91 2455.67 3980.61 3738.67 TRUE FALSE FALSE 3459.41769 3642.861837 3192.4571 3706.380261 3186.514339 3962.388826 3810.915918 3204.392478 3543.947042 3868.588504 0.894232531 0.941651414 0.825225298 0.958070432 0.82368914 1.024246653 0.985092086 0.8283105 0.91608271 1 11.91759156 -9.317486323 0.954948353 1.001935182 0.912181223 0.013807984 0.070756383 0.747978209 1.179560424 0.047532137 0.011579968 4.81E-10 9.317486323 -0.08975396 EAEGAPQVEAGKR ddPTM_HeLa_Curcumin_4h_R1 1 EAEGAPQVEAGKR 13 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1;C9J813 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 0 0 77.279 0.012845 4426400 990.85 810.12 873.89 1073.4 1094.6 1012.9 859.65 1086 1208.3 1017.5 FALSE FALSE TRUE 912.423177 880.143163 906.2771322 1068.958555 1081.54761 802.8131223 883.7694654 1417.116401 1075.752513 1052.858049 0.866615569 0.835956152 0.860778082 1.015292191 1.02724922 0.762508415 0.839400398 1.345970999 1.021745062 1 10.04009522 -4.254839195 24.72618802 0.918740293 1.345971226 0.671448188 0.09052217 311.8596399 1168279.307 0.012913527 0.16554982 5.56E-05 4.254839195 0.427230933 EAEGSSAEYK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 EAEGSSAEYKK 11 1 P49321-4;P49321;P49321-3;H0YDS9;E9PRH9;H0YF33;Q5T624;P49321-2 P49321-4 NASP Nuclear autoantigenic sperm protein 0 1 EAEGSSAEYK(1)K 104.79 0.0021235 1097800 813.66 939.57 600.42 744.47 1033.3 697.64 730.79 637.28 992.5 782.96 FALSE TRUE FALSE 749.2579524 1020.782244 622.6720934 741.3895804 1020.978572 552.9416 751.2940006 831.5837383 883.6252331 810.1678017 0.92481823 1.259963975 0.76857176 0.915106202 1.260206306 0.682502562 0.927331349 1.026433952 1.090669404 1 9.662076939 -5.228663582 24.99674545 0.984652305 0.883613627 0.106675539 0.167649606 1385.560711 1056708.035 0.021676135 0.055259445 5.91E-06 5.228663582 -0.101038678 EAELDVNEELDKK ddPTM_HeLa_Curcumin_4h_R1 1 EAELDVNEELDKK 13 1 P43034;I3L495 P43034 PAFAH1B1 Platelet-activating factor acetylhydrolase IB subunit alpha 0 0 127.3 0.0026867 7691100 1886.6 1517.1 1898.5 1851.5 1712.2 2153.2 1884.8 1555.4 2019.3 1910.8 FALSE FALSE TRUE 1737.273619 1648.231364 1968.86008 1843.838984 1691.783133 1706.602048 1937.682415 2029.6343 1797.787842 1977.200158 0.878653389 0.833618871 0.995781875 0.932550494 0.855645862 0.863140761 0.980013282 1.02651939 0.909259407 1 10.94924321 -9.472245779 1.248367302 0.999381953 0.914524801 0 0.067213395 0.598686271 1.688171692 0.042509027 0.010774319 3.37E-10 9.472245779 -0.084857151 EAELLTS(ph)AEKR ddPTM_HeLa_Curcumin_4h_R1 1 EAELLTSAEKR 11 1 O60566-2;O60566;O60566-3 O60566-2 BUB1B Mitotic checkpoint serine/threonine-protein kinase BUB1 beta 1 0 EAELLT(0.123)S(0.877)AEKR 173.04 1.21E-14 0 7526.7 7202.1 7186.5 7685.6 7738.9 11725 9708.1 3518.4 8370.8 7498 TRUE FALSE FALSE 6930.953753 7824.617432 7452.838012 7653.799024 7646.618672 9293.102832 9980.483158 4591.143963 7452.544183 7758.554942 0.893330498 1.008514793 0.960596151 0.986498012 0.985572536 1.197787849 1.286384286 0.591752459 0.960558279 1 12.92157226 -5.505335975 23.73532165 0.957759132 1.058126539 0.008710159 0.172761381 841.6237018 1138711.345 0.022945523 0.05023154 3.12E-06 5.505335975 0.100367407 EAENQGLDIS(ph)SPGMSGHR ddPTM_HeLa_Curcumin_4h_R1 1 EAENQGLDISSPGMSGHR 18 0 Q15545 Q15545 TAF7 Transcription initiation factor TFIID subunit 7 1 0 EAENQGLDIS(0.903)S(0.097)PGMSGHR 127.74 0.00011156 0 1235 1120.9 963.63 1195.1 1623.8 1506.1 846.76 1260.8 1454 897.49 TRUE FALSE FALSE 1137.248447 1217.785601 999.3429755 1190.154993 1604.437246 1193.717883 870.5178067 1645.212116 1294.499838 928.6777107 1.224588933 1.311311327 1.076092345 1.281558693 1.727657752 1.285395212 0.937373425 1.771564125 1.393917204 1 9.859034199 -12.46944918 0.081069926 4.95E-12 1.69715267 0 0.263089744 141.5618242 1.095469765 27.87045373 4.404633565 3.39E-13 12.46944918 1.69715267 EAEQAASEAAGGDTT(ph)PGSS(ph)PSSLYYEEPLGQPPR ddPTM_HeLa_Curcumin_4h_R1 2 EAEQAASEAAGGDTTPGSSPSSLYYEEPLGQPPR 34 0 Q86TC9;Q86TC9-3 Q86TC9 MYPN Myopalladin 2 0 EAEQAASEAAGGDT(0.447)T(0.555)PGS(0.19)S(0.675)PS(0.11)S(0.019)LY(0.003)YEEPLGQPPR;EAEQAASEAAGGDT(0.224)T(0.747)PGS(0.253)S(0.543)PS(0.157)S(0.052)LY(0.016)Y(0.006)EEPLGQPPR ; 116.27 5.49E-18 18556000 3072.45 2846.81 2785.03 2972.36 3090.71 3581.58 2631.49 1403.09 3311.8 2552.11 TRUE FALSE FALSE 2829.26234 3092.875571 2888.245662 2960.061162 3053.855302 2838.719935 2705.322527 1830.885682 2948.503826 2640.795633 1.071367396 1.171190808 1.093702832 1.120897477 1.156414856 1.074948739 1.024434642 0.693308357 1.116521017 1 11.36675694 -4.259586581 3.580685119 1.065443319 0.649492331 0.820048689 0.05511135 0.111609409 2.533145526 0.009284297 0.124476607 5.50E-05 4.259586581 -0.415950988 EAETEPHEGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 EAETEPHEGKR 11 1 P41223;P41223-2 P41223 BUD31 Protein BUD31 homolog 0 1 ; EAETEPHEGK(1)R;EAETEPHEGK(1)R 107.06 0.0011917 2245700 2359.9 2756 1919.79 1762.66 2034.78 3218.8 1956.09 1822.22 2531.1 2008.89 FALSE TRUE FALSE 2173.111425 2994.21636 1990.939106 1755.36658 2010.516577 2551.184597 2010.972621 2377.80649 2253.444663 2078.698778 1.045419109 1.44042821 0.957781439 0.844454521 0.967199576 1.227298839 0.967418965 1.143891801 1.084065035 1 11.021465 -7.933412693 2.83999217 1.015066625 1.07204288 0.000989389 0.160428523 0.893593692 14.51594359 0.032262108 0.030265221 1.17E-08 7.933412693 0.056976255 EAETPQAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EAETPQAKK 9 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 1 ; EAETPQAK(1)K;EAETPQAK(1)K 126.07 0.00030005 20253000 9264.4 7730.4 8641.4 8368.5 8363.4 10710.3 9238.5 9998.6 9990.6 8127.1 FALSE TRUE FALSE 8531.112964 8398.58133 8961.657886 8333.873364 8263.671917 8488.86305 9497.707446 13047.12711 8894.656175 8409.51612 1.014459434 0.998699712 1.065656782 0.9910051 0.982657242 1.009435374 1.129399993 1.5514718 1.057689414 1 13.03780708 -4.244138038 2.294652785 1.007729278 1.701522249 0.972966132 0.02677115 0.05449251 0.320244591 0.003044809 0.07699465 5.70E-05 4.244138038 0.693792972 EAFAQRPS(ph)SAPDLMCLS(ph)PDRK ddPTM_HeLa_Curcumin_4h_R1 1 EAFAQRPSSAPDLMCLSPDRK 21 2 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 2 0 EAFAQRPS(0.775)S(0.225)APDLMCLS(1)PDRK 57.735 0.010894 230110000 2326.6 1871.2 2152.7 2669.3 2001 2470.1 2143.8 1707.2 2864.9 2564.9 TRUE FALSE FALSE 2142.447155 2032.93819 2232.480956 2658.255144 1977.139382 1957.773416 2203.949258 2227.717421 2550.627638 2654.030084 0.80724298 0.765981592 0.841166409 1.001591941 0.744957412 0.737660597 0.83041608 0.839371578 0.96103946 1 11.37396901 -9.21724376 0.77375927 1.010488983 0.819769235 0.438902089 0.071393035 0.541171087 0.53490469 0.064502554 0.014691835 6.06E-10 9.21724376 -0.190719748 EAFAQRPSS(ph)APDLMCLS(ph)PDRK ddPTM_HeLa_Curcumin_4h_R1 1 EAFAQRPSSAPDLMCLSPDRK 21 2 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4;P30305-3 G8JLH2 CDC25B M-phase inducer phosphatase 2 2 0 EAFAQRPS(0.464)S(0.536)APDLMCLS(1)PDRK 72.302 0.0019801 412580000 3116.8 2540 3153.7 3573.4 2649.2 3593.4 2954.5 2255.6 4637 3574.4 TRUE FALSE FALSE 2870.101991 2759.546282 3270.578896 3558.614218 2617.61002 2848.088334 3037.395318 2943.322056 4128.332701 3698.610134 0.775994735 0.746103585 0.88427241 0.962149048 0.707728018 0.770042862 0.821226139 0.795791378 1.116184878 1 11.85276752 -9.292960114 0.897022101 1.006496848 0.807612101 0.594120633 0.078841032 0.415664824 0.568955477 0.056531551 0.013399252 5.09E-10 9.292960114 -0.198884747 EAFDEVDMAHR ddPTM_HeLa_Curcumin_4h_R1 1 EAFDEVDMAHR 11 0 Q9NX46 Q9NX46 ADPRHL2 Poly(ADP-ribose) glycohydrolase ARH3 0 0 102.4 0.007683 5598800 4477.2 3884.6 4109 3933.1 4305.9 6173.1 3845.9 4113.9 5190.4 4544.5 FALSE FALSE TRUE 4122.824896 4220.367515 4261.283155 3916.825874 4254.554955 4892.729475 3953.805603 5368.209172 4621.026106 4702.421037 0.876745162 0.897488226 0.906189199 0.832938149 0.904758405 1.04047031 0.840802126 1.141584118 0.982690846 1 12.199188 -4.246062406 24.12670999 0.927186609 1.141584374 0.510111411 0.064754162 1227.271582 1925557.235 0.009537417 0.292609059 5.67E-05 4.246062406 0.214397765 EAFNMIDQNR ddPTM_HeLa_Curcumin_4h_R1 2 EAFNMIDQNR 10 0 J3QRS3;P19105;O14950;J3KTJ1;P24844;P24844-2 J3QRS3;P24844 MYL12A;MYL12B;MYL9 Myosin regulatory light chain 12A;Myosin regulatory light chain 12B;Myosin regulatory light polypeptide 9 0 0 ; ; 163.38 2.10E-09 7784200 3457.9 3039.7 3185.1 2787 3515.2 4439.4 3176.9 3492.4 3074 2475.5 FALSE FALSE TRUE 3184.203566 3302.438123 3303.142608 2775.468132 3473.283536 3518.618398 3266.035264 4557.216683 2736.789891 2561.523441 1.243089763 1.289247668 1.289522694 1.083522441 1.355944467 1.373642865 1.275036258 1.779104033 1.068422739 1 11.32278638 -1 0.155281052 0.99092559 3.09926747 0.633689745 0.125035399 33.05409881 0.328040238 0.247722532 15.89620889 0.1 1 2.10834188 EAFQLFDR ddPTM_HeLa_Curcumin_4h_R1 2 EAFQLFDR 8 0 P60660-2;F8W1R7;G8JLA2;G3V1V0;P60660;G3V1Y7;J3KND3;B7Z6Z4 P60660-2 MYL6 Myosin light polypeptide 6 0 0 ; ; 112.11 0.0053315 16395300 5828.7 4247.4 4852.9 4990.2 5131.9 7103.4 5481.5 5423.3 5052.9 4672.9 FALSE FALSE TRUE 5367.352245 4614.52633 5032.752743 4969.551875 5070.705444 5630.074768 5635.296137 7076.839204 4498.609512 4835.282927 1.110038921 0.954344637 1.040839351 1.027768581 1.048688468 1.164373389 1.165453237 1.463583271 0.930371517 1 12.23938459 -2.208622346 0.789083515 1.041767541 12.36209239 0.846896313 0.056859925 14.34553087 0.404060641 0.008454802 267.1936489 0.00618554 2.208622346 11.32032484 EAFSLFDKDGDGTITTK ddPTM_HeLa_Curcumin_4h_R1 2 EAFSLFDKDGDGTITTK 17 1 P0DP25;P0DP24;P0DP23;E7EMB3;F8WBR5;M0QZ52;G3V479 P0DP25 CALM2;CALM3;CALM1 0 0 ; ; 167.29 7.97E-05 215950000 3647.2 2599.5 3004.2 3237.5 3628.5 3603.5 3492.8 3788.9 3593.2 3092.1 FALSE FALSE TRUE 3358.520271 2824.189197 3115.538295 3224.104083 3585.232507 2856.09348 3590.798568 4944.118168 3199.03495 3199.550245 1.049685116 0.882683184 0.973742575 1.007674153 1.120542649 0.892654674 1.122282287 1.545254111 0.999838948 1 11.64365341 -4.294717423 3.250730611 1.00892204 1.601500105 0.855669566 0.067956125 0.076989176 1.317970492 0.00908634 0.109142307 5.07E-05 4.294717423 0.592578065 EAFTNKPNVFTVVTR ddPTM_HeLa_Curcumin_4h_R1 2 EAFTNKPNVFTVVTR 15 1 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 83.633 0.012181 5725300 1002.91 919.14 765.96 1241.75 1285.81 1617.63 878.57 1150.72 1351.04 1092.88 FALSE FALSE TRUE 923.5286152 998.586366 794.3471514 1236.611968 1270.477556 1282.115304 903.2203096 1501.569231 1202.834292 1130.857499 0.816662238 0.883034659 0.702429044 1.09351706 1.123463882 1.133754965 0.798703913 1.327814718 1.063647978 1 10.14320143 -6.194444711 24.99899204 0.894075723 1.082649498 0.30806398 0.150978385 181.5148522 67731.73604 0.021288008 0.035302166 6.39E-07 6.194444711 0.188573775 EAGAGGLAIAVEGPSK ddPTM_HeLa_Curcumin_4h_R1 1 EAGAGGLAIAVEGPSK 16 0 P21333-2;P21333;H0Y5C6;Q60FE5 P21333-2;Q60FE5 FLNA Filamin-A 0 0 262.64 5.96E-63 1371500 1180.1 1128.7 1320.5 1222.9 1171.5 1381.6 1142.7 1084.4 1089.8 1105.9 FALSE FALSE TRUE 1086.69384 1226.259799 1369.438892 1217.839964 1157.530628 1095.040586 1174.761087 1415.028568 970.2516665 1144.329943 0.949633317 1.071596358 1.196716821 1.064238484 1.011535733 0.956927321 1.026592981 1.236556447 0.847877549 1 10.16028737 -7.249427257 22.60458354 0.976215737 1.074942471 0.3363981 0.088939594 224.0290367 421579.7542 0.01356511 0.016526326 5.63E-08 7.249427257 0.098726734 EAGDVCYADVYR ddPTM_HeLa_Curcumin_4h_R1 4 EAGDVCYADVYR 12 0 J3KTL2;Q07955;Q07955-3;Q07955-2;J3KSR8 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 0 ;;; ;;; 193.83 1.19E-06 99367600 5071.83 4011.56 4274.25 4215.26 4656.33 6201.7 4824.4 4555.87 4775.84 4441.66 FALSE FALSE TRUE 4670.389304 4358.301371 4432.657465 4197.818371 4600.806306 4915.397512 4959.75968 5944.93379 4251.942301 4596.007354 1.016184036 0.948279895 0.964458305 0.913361979 1.001044157 1.069492961 1.079145288 1.293499625 0.925138272 1 12.16616539 -3.854547012 1.105259059 0.993415532 1.723624175 0.842857314 0.04159713 1.024460108 0.546593204 0.005973163 1.080961767 0.000139783 3.854547012 0.730208644 EAGELPT(ph)SPLHLLSPGTPR ddPTM_HeLa_Curcumin_4h_R1 1 EAGELPTSPLHLLSPGTPR 19 0 H7C228;Q969R5-2;Q969R5-3;Q969R5 H7C228 L3MBTL2 Lethal(3)malignant brain tumor-like protein 2 1 0 EAGELPT(0.608)S(0.392)PLHLLSPGTPR 90.592 0.0017573 3755700 1527.5 1512.9 1512.6 1199.5 1959.5 2099.5 1425.9 1611.4 1597.3 1542.4 TRUE FALSE FALSE 1406.596763 1643.668335 1568.658287 1194.536787 1936.134242 1664.040034 1465.906916 2102.708442 1422.080186 1595.998285 0.88132724 1.029868484 0.982869657 0.748457438 1.213117997 1.04263272 0.91848903 1.317487908 0.891028643 1 10.64024339 -2.257065354 1.575470477 0.959136057 199.9999999 0.426347304 0.118559563 552.4772357 3.071423303 0.01643675 395850.2733 0.005532668 2.257065354 199.0408638 EAGELPTS(ph)PLHLLSPGTPR ddPTM_HeLa_Curcumin_4h_R1 1 EAGELPTSPLHLLSPGTPR 19 0 H7C228;Q969R5-2;Q969R5-3;Q969R5 H7C228 L3MBTL2 Lethal(3)malignant brain tumor-like protein 2 1 0 EAGELPT(0.11)S(0.89)PLHLLSPGTPR 112.64 0.00018717 2026600 1017.3 935.92 867.42 1135.8 1314.9 1250.3 1030.5 1046.9 1011.6 890.09 TRUE FALSE FALSE 936.7796315 1016.816754 899.5673483 1131.100361 1299.220676 990.9736862 1059.413057 1366.094991 900.6300109 921.0205612 1.017110444 1.104010917 0.976707129 1.228094581 1.410631566 1.075951752 1.150259941 1.483240492 0.977860917 1 9.847089554 -6.204231355 5.545543049 1.014873187 1.262350344 0.555592001 0.113899249 0.12493396 8.343430672 0.016286134 0.027095037 6.25E-07 6.204231355 0.247477157 EAGEMESSTLQES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 EAGEMESSTLQESPR 15 0 Q2M1Z3 Q2M1Z3 ARHGAP31 Rho GTPase-activating protein 31 1 0 EAGEMESST(0.001)LQES(0.999)PR 194.67 6.07E-23 0 417.8 333.44 370.03 502.33 349.5 411.41 411.53 254.89 503.1 337.02 TRUE FALSE FALSE 384.7306891 362.2610678 383.7436373 500.2514916 345.3324408 326.0789285 423.0764242 332.6047876 447.9111887 348.7314199 1.103229211 1.038796756 1.100398804 1.434489303 0.990253304 0.935043159 1.213186997 0.953756297 1.284401586 1 8.445972543 -1.26846085 11.63465835 1.071392602 1.096052787 0 0.156315409 0 0 0.018048953 0 0.053893843 1.26846085 0.024660185 EAGENAPVLS(ph)DDELVSMSVR ddPTM_HeLa_Curcumin_4h_R1 4 EAGENAPVLSDDELVSMSVR 20 0 O60675 O60675 MAFK Transcription factor MafK 1 0 EAGENAPVLS(0.996)DDELVS(0.001)MS(0.003)VR;EAGENAPVLS(0.993)DDELVS(0.006)MSVR;EAGENAPVLS(1)DDELVSMSVR;EAGENAPVLS(1)DDELVSMSVR ;;; 250.38 1.42E-43 63762200 9492.1 7028.8 7500.6 7936.9 8153.1 9980.5 7682.4 5156.36 9371.6 8260.75 TRUE FALSE FALSE 8740.790269 7636.338152 7778.578834 7904.059211 8055.879607 7910.431797 7897.947468 6728.510427 8343.558927 8547.810448 1.022576521 0.893367746 0.910008344 0.924688171 0.942449491 0.925433694 0.923973164 0.787161867 0.976104814 1 13.0613392 -1 0.196930414 1.02561292 0.131118505 0.517398972 0.042811159 26.65648934 0.303488627 0.045571889 7.378440315 0.1 1 -0.894494415 EAGEQGDIEPR ddPTM_HeLa_Curcumin_4h_R1 4 EAGEQGDIEPR 11 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 0 0 ;;; ;;; 157.97 0.001316 54433000 12491.3 10643.9 10584.4 10583.8 10295.4 13945.5 10676.6 10372.8 12109.1 11047.2 FALSE FALSE TRUE 11502.60042 11563.91129 10976.66717 10540.00704 10172.63408 11053.0461 10976.15666 13535.41897 10780.76203 11431.08938 1.006255838 1.011619357 0.960246816 0.92204747 0.889909417 0.9669285 0.960202156 1.184088281 0.943108891 1 13.48067528 -4.257395819 24.78406362 0.983270296 1.18408837 0.703161117 0.041253594 179.3948295 1099510.488 0.006418729 0.065015953 5.53E-05 4.257395819 0.200818074 EAGET(ph)VPPDT(ph)SKMLK ddPTM_HeLa_Curcumin_4h_R1 1 EAGETVPPDTSKMLK 15 1 Q9Y2B5;Q9Y2B5-2 Q9Y2B5 VPS9D1 VPS9 domain-containing protein 1 2 0 EAGET(1)VPPDT(0.5)S(0.5)KMLK 75.387 0.0060433 0 1496.3 1571.4 1384.6 1365.2 1633.5 1537.9 842.92 609.69 1333.6 1228.6 TRUE FALSE FALSE 1377.866276 1707.224814 1435.914494 1359.551164 1614.021579 1218.922204 866.5700666 795.5816743 1187.307417 1271.293759 1.08382997 1.342903481 1.129490713 1.069423298 1.269589793 0.958804522 0.681644239 0.625804751 0.933936322 1 10.31208172 -4.827686399 3.333983779 1.087055296 0.639396625 0.711892246 0.115795188 0.098714403 2.167834173 0.016643303 0.062262642 1.49E-05 4.827686399 -0.447658671 EAGGGGVGGPGAK ddPTM_HeLa_Curcumin_4h_R1 2 EAGGGGVGGPGAK 13 0 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 0 ; ; 180.07 1.18E-08 11729000 7423.2 7949.1 6473 5596.7 5218.6 6278.3 5290.8 4631.8 6122.6 7017.5 FALSE FALSE TRUE 6835.645887 8636.184783 6712.895074 5573.542338 5156.371603 4976.109809 5439.245609 6044.014498 5450.966098 7261.357603 0.941372986 1.18933473 0.924468321 0.767562024 0.710111233 0.685286427 0.74906731 0.832353236 0.750681401 1 12.82602359 -6.308549614 3.747725218 0.990103808 0.741144624 0.496601563 0.106461022 0.09636811 2.828780201 0.0119014 0.01898387 4.91E-07 6.308549614 -0.248959184 EAGS(ph)PAQEFK ddPTM_HeLa_Curcumin_4h_R1 3 EAGSPAQEFK 10 0 Q5JSZ5;Q5JSZ5-5;Q5JT00 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 EAGS(1)PAQEFK;EAGS(1)PAQEFK;EAGS(1)PAQEFK ;; 147.73 0.00096218 257762000 14982.8 12231.9 14432.2 13277.2 15300.2 15958.5 14022.4 6233.5 13391.7 11317.3 TRUE FALSE FALSE 13796.89557 13289.17093 14967.07003 13222.26246 15117.75511 12648.52721 14415.8308 8134.065454 11922.66401 11710.57533 1.178156937 1.134800858 1.278081529 1.12908735 1.290948965 1.080094432 1.231009613 0.694591446 1.018110868 1 13.51552434 -4.252652382 24.59477975 1.125865104 0.694591168 0.658526942 0.096876483 494.4147882 1383827.495 0.014809459 0.233536874 5.59E-05 4.252652382 -0.431273936 EAGSTSDSPSS(ph)PEFFL ddPTM_HeLa_Curcumin_4h_R1 1 EAGSTSDSPSSPEFFL 16 0 Q9Y5Q3 Q9Y5Q3 MAFB Transcription factor MafB 1 0 EAGS(0.001)T(0.002)S(0.01)DS(0.285)PS(0.089)S(0.613)PEFFL 96.23 0.0038876 824790 494.8 437.27 596.24 469.07 500.21 608.06 290.55 390.54 402.79 494.05 TRUE FALSE FALSE 455.6360579 475.0656704 618.3371789 467.1291126 494.2453224 481.9415018 298.702051 509.6138482 358.6049447 511.2182007 0.89127511 0.929281606 1.209536707 0.913756811 0.966799151 0.942731501 0.584294633 0.996861707 0.701471396 1 8.997795391 -4.965169561 24.99814791 0.96413302 0.783811619 0.134983352 0.149921871 169.8740565 121918.556 0.016253972 0.048761664 1.08E-05 4.965169561 -0.180321401 EAGT(ph)PSLDSEAK ddPTM_HeLa_Curcumin_4h_R1 2 EAGTPSLDSEAK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 0 EAGT(0.982)PS(0.017)LDS(0.001)EAK;EAGT(0.995)PS(0.005)LDSEAK ; 164.53 0.00034418 48409000 9272.1 7100.7 9106.3 9336 8969.3 10196.1 9442.6 1993.04 7690.9 5604.5 TRUE FALSE FALSE 8538.203501 7714.452868 9443.787489 9297.370106 8862.346956 8081.313926 9707.533943 2600.708721 6847.227512 5799.255958 1.472292922 1.330248729 1.628448125 1.603200509 1.528186895 1.393508751 1.673927485 0.448455585 1.180707932 1 12.5016521 -9.244793698 0.890633138 0.990245774 1.415748262 0.09502951 0.336831861 0.822200213 1.129113609 0.234316132 0.058917971 5.69E-10 9.244793698 0.425502488 EAIEGTYIDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EAIEGTYIDKK 11 1 P62280;M0QZC5 P62280 RPS11 40S ribosomal protein S11 0 1 ; EAIEGTYIDK(1)K;EAIEGTYIDK(1)K 228.98 1.14E-40 10875100 3269.6 4382.6 2751 2887.5 6063 7364.9 5365.5 4770.5 7086.6 2963.5 FALSE TRUE FALSE 3010.80771 4761.412416 2852.95448 2875.55229 5990.702685 5837.33672 5516.041489 6225.003489 6309.21771 3066.481404 0.981844438 1.552728286 0.930367448 0.937736745 1.953608027 1.903594365 1.798817851 2.030015079 2.057477897 1 11.58236849 -5.759480132 24.99999966 1.029558162 1.911465727 0.375244199 0.371527642 14.09216599 179811.3337 0.026451805 0.050849709 1.74E-06 5.759480132 0.881907565 EAIEGTYIDKK ddPTM_HeLa_Curcumin_4h_R1 4 EAIEGTYIDKK 11 1 P62280;M0QZC5 P62280 RPS11 40S ribosomal protein S11 0 0 ;;; ;;; 130.01 0.0041672 89422100 7299.7 6461.42 7126.2 6994.12 6601.3 8583.4 7204.3 5683.48 8621.8 7694.03 FALSE FALSE TRUE 6721.921042 7019.916353 7390.303241 6965.180185 6522.583809 6803.106085 7406.433269 7416.346888 7676.010111 7961.39697 0.844314266 0.881744294 0.928267146 0.874869098 0.819276295 0.854511603 0.930293176 0.931538387 0.96415367 1 12.95880588 -9.397087828 1.05148307 1.001986561 0.879727194 0.516869065 0.037684672 0.318024594 0.612547506 0.029550162 0.007062334 4.01E-10 9.397087828 -0.122259367 EAIS(ph)DEDEDEALYQK ddPTM_HeLa_Curcumin_4h_R1 2 EAISDEDEDEALYQK 15 0 Q9C0B7 Q9C0B7 TANGO6 Transport and Golgi organization protein 6 homolog 1 0 EAIS(1)DEDEDEALYQK;EAIS(1)DEDEDEALYQK ; 232.28 4.90E-21 16125200 4193.9 3442.8 3357.8 3803.2 3556.2 3564 2666.1 2834.3 3301.7 3705.7 TRUE FALSE FALSE 3861.94839 3740.380291 3482.243022 3787.463366 3513.794638 2824.786225 2740.903591 3698.465022 2939.51177 3834.472799 1.007165415 0.975461422 0.908141276 0.987740314 0.916369687 0.736681774 0.714805851 0.964530254 0.766601284 1 11.90481252 -5.494357017 3.630243516 0.991789282 0.797178311 0.176713314 0.098601142 0.11016069 3.049422797 0.009536284 0.021586449 3.20E-06 5.494357017 -0.194610971 EALAEAALES(ph)PRPALVR ddPTM_HeLa_Curcumin_4h_R1 4 EALAEAALESPRPALVR 17 1 J3QRP6;O14745-2;O14745 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 1 0 EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR;EALAEAALES(1)PRPALVR ;;; 142.4 0.0030581 1129193000 10759.5 8559.7 8569.5 8881.7 8483.9 11319.3 8013.2 5345.32 10174.1 8979.6 TRUE FALSE FALSE 9907.874222 9299.562327 8887.093208 8844.949879 8382.735034 8971.549585 8238.028826 6975.083461 9058.026684 9291.640432 1.066321313 1.000852583 0.956461162 0.951925545 0.902180309 0.965550664 0.886606503 0.750683748 0.974857642 1 13.18171761 -2.709485342 0.385791458 1.030092533 2.08E-18 0.758009362 0.039768658 5.602006519 0.227653552 0.011401206 3.470570829 0.001952157 2.709485342 -1.030092533 EALAEAALESPRPALVR ddPTM_HeLa_Curcumin_4h_R1 1 EALAEAALESPRPALVR 17 1 J3QRP6;O14745-2;O14745 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 0 0 119.62 0.00056952 3717800 3069.5 3028.2 2603.6 2945.2 2664 2868 2381 2187.6 2843 2518 FALSE FALSE TRUE 2826.545836 3289.944115 2700.091706 2933.013543 2632.23354 2273.144471 2447.804452 2854.58917 2531.130013 2605.500313 1.084838034 1.26269189 1.036304503 1.125700707 1.010260305 0.872440683 0.939475785 1.095601162 0.971456423 1 11.34734471 -5.525054726 24.36785792 1.064722672 0.962060803 0.22371788 0.091315303 59.41731429 665388.0121 0.013362561 0.026875237 2.99E-06 5.525054726 -0.102661869 EALEK(ac)TEK ddPTM_HeLa_Curcumin_4h_R1 1 EALEKTEK 8 1 O43707;O43707-2;F5GXS2;O43707-3 O43707 ACTN4 Alpha-actinin-4 0 1 EALEK(1)TEK 98.044 0.014938 3190600 786.09 730.45 914.31 780.47 1005.3 1196.1 903.12 985.14 757.94 769.22 FALSE TRUE FALSE 723.870147 793.5868432 948.1951329 777.2406219 993.3124541 948.0153772 928.4591166 1285.504651 674.7958783 795.9503377 0.909441347 0.9970306 1.191274239 0.976493865 1.247957827 1.191048401 1.166478702 1.615056355 0.847786409 1 9.636534608 -1 0.381500234 0.959758619 9.333653675 0.758099461 0.103397816 20.16726987 0.244381902 0.025084795 126.506806 0.1 1 8.373895056 EALGIPAAASFK ddPTM_HeLa_Curcumin_4h_R1 2 EALGIPAAASFK 12 0 P31939-2;P31939 P31939-2 ATIC Bifunctional purine biosynthesis protein PURH;Phosphoribosylaminoimidazolecarboxamide formyltransferase;IMP cyclohydrolase 0 0 ; ; 132.32 0.00037845 2386910 4447 3276.3 4271.4 4084.3 4241.5 5104.4 4463.2 3763.8 4315.7 4608.8 FALSE FALSE TRUE 4095.015258 3559.488773 4429.701842 4067.400249 4190.922883 4045.689902 4588.42538 4911.365294 3842.278507 4768.955457 0.8586818 0.746387507 0.928862071 0.852891222 0.878792625 0.84833879 0.962144734 1.029861851 0.805685551 1 12.21945759 -3.336974017 14.57006954 0.912741479 0.90094557 0 0.086585874 0 0 0.011904248 0 0.000460284 3.336974017 -0.011795909 HEDEQALLDQNSQT(ph)PPPS(ph)PFSVQAFNK ddPTM_HeLa_Curcumin_4h_R1 1 HEDEQALLDQNSQTPPPSPFSVQAFNK 27 0 A0A499FJI4;O75592-2;O75592;A0A087WY34 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 2 0 HEDEQALLDQNS(0.237)QT(0.809)PPPS(0.897)PFS(0.058)VQAFNK 94.594 4.53E-06 7076500 1299.8 1632.2 1862.4 1509.5 1287.9 2043.6 2604.4 4159.5 1918.1 2216.1 TRUE FALSE FALSE 1196.919458 1773.280095 1931.422182 1503.254089 1272.542634 1619.734324 2677.472455 5427.712402 1707.689229 2293.10931 0.521963542 0.77330814 0.842272182 0.655552739 0.554941986 0.706348501 1.167616582 2.366966275 0.744704677 1 11.16308941 -4.28139953 2.380140158 0.747050717 2.707750163 0.932669471 0.132949824 0.13381169 0.934114173 0.026816082 0.528407605 5.23E-05 4.28139953 1.960699446 up EALGQNEES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 EALGQNEESPK 11 0 Q9H8Y5;B8ZZS4 Q9H8Y5 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 0 EALGQNEES(1)PK 120.87 0.0040857 11435000 3014.8 3038.3 3018.3 2535.7 2544.8 2787.7 2411.4 2320.4 2560.3 2617.3 TRUE FALSE FALSE 2776.175399 3300.917114 3130.160853 2525.207945 2514.454922 2209.499596 2479.057394 3027.879278 2279.441496 2708.25098 1.025080548 1.218837227 1.155786844 0.932412824 0.928442357 0.815840043 0.915372103 1.118020191 0.84166553 1 11.40314573 -6.114472358 24.06901386 1.040922129 0.932752318 0.169585238 0.116099115 19.47888171 4057.92456 0.015748324 0.026115653 7.68E-07 6.114472358 -0.108169811 EALNSCNK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 EALNSCNKR 9 1 P19338;H7BY16 P19338 NCL Nucleolin 0 1 EALNSCNK(1)R 89.047 0.0080855 1163600 290.48 415.17 266.3 350.15 246.43 326.08 264.76 421.88 374.15 249.59 FALSE TRUE FALSE 267.4882015 451.0554448 276.1693123 348.7011721 243.4914832 258.4473323 272.188453 550.5092699 333.1066811 258.2632339 1.035719244 1.746494993 1.069332665 1.350177363 0.942803509 1.000712832 1.053918705 2.131582036 1.289795206 1 8.012698467 -4.260309362 24.63929989 1.087379789 2.131582448 0.573224871 0.241791291 38.25869872 834071.1355 0.032461098 0.266860301 5.49E-05 4.260309362 1.044202659 EALPWGLEPQDVQSSDEMRS(ph)PEGYLR ddPTM_HeLa_Curcumin_4h_R1 1 EALPWGLEPQDVQSSDEMRSPEGYLR 26 1 Q9H5H4 Q9H5H4 ZNF768 Zinc finger protein 768 1 0 EALPWGLEPQDVQS(0.191)S(0.167)DEMRS(0.593)PEGY(0.049)LR 53.905 0.017581 8492000 1140.1 1032.9 1271.2 1156.6 1321.4 1468.7 1313.2 835.53 1245.2 1128.2 TRUE FALSE FALSE 1049.859882 1122.179273 1318.31179 1151.814296 1305.643168 1164.075064 1350.044858 1090.279251 1108.604675 1167.404866 0.899310867 0.961259719 1.129267 0.986645104 1.118415047 0.997147689 1.156449572 0.933934132 0.949631707 1 10.18908927 -6.881671743 8.688136141 0.951327529 1.055519824 0.340565568 0.068996929 0.214658283 15.48792676 0.010813706 0.01422683 1.31E-07 6.881671743 0.104192294 EALS(ph)GGEASLVEK ddPTM_HeLa_Curcumin_4h_R1 1 EALSGGEASLVEK 13 0 Q96T17;Q96T17-2;Q96T17-5;Q96T17-4 Q96T17 MAP7D2 MAP7 domain-containing protein 2 1 0 EALS(1)GGEASLVEK 128.22 0.0017712 2136300 1612.8 1742.1 1630.6 1808.1 2038.2 2000.3 1716.8 1092.7 1734.4 1969.6 TRUE FALSE FALSE 1485.145178 1892.679361 1691.03147 1800.618561 2013.895796 1585.415232 1764.968787 1425.8592 1544.140659 2038.043453 0.728711243 0.928674685 0.829732785 0.883503518 0.988151549 0.777910417 0.866011362 0.699621589 0.757658359 1 10.9929691 -9.593726652 1.3908458 0.999876156 0.829889161 0 0.111238794 0.385457676 1.339235047 0.060779854 0.014138877 2.55E-10 9.593726652 -0.169986994 EALS(ph)PCPSTVSTK ddPTM_HeLa_Curcumin_4h_R1 1 EALSPCPSTVSTK 13 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 0 EALS(0.999)PCPS(0.001)TVSTK 88.092 0.014291 37390000 5091.6 3396.1 3803 4024 3053.2 2520 1632.6 1437.3 4291.2 3323.2 TRUE FALSE FALSE 4688.594487 3689.643751 3943.942525 4007.349754 3016.792584 1997.323594 1678.406362 1875.526153 3820.466096 3438.680953 1.363486334 1.072982287 1.146934705 1.16537411 0.877310988 0.580840043 0.488095984 0.545420229 1.111026626 1 11.74763955 -5.451695654 2.006800465 1.166958111 0.513233413 0.898055037 0.091212056 0.102743376 0.807588222 0.020426634 0.055043902 3.53E-06 5.451695654 -0.653724698 EALTYDGALLGDR ddPTM_HeLa_Curcumin_4h_R1 3 EALTYDGALLGDR 13 0 Q15056;Q15056-2 Q15056 EIF4H Eukaryotic translation initiation factor 4H 0 0 ;; ;; 203.03 6.28E-08 15503500 3782.86 3610.65 3826.21 3778.11 4150.08 4895.56 4046.24 3513.85 3628.33 3475.06 FALSE FALSE TRUE 3483.442639 3922.738497 3968.012708 3762.477182 4100.593007 3880.165672 4159.766605 4585.206689 3230.311277 3595.818076 0.968748297 1.090916841 1.103507637 1.046348036 1.140378328 1.079077303 1.156834555 1.275149797 0.898352255 1 11.81210432 -1 0.251678245 0.975438066 2.757778143 0.762000076 0.049039459 15.87884612 0.198474748 0.024585428 12.15247419 0.1 1 1.782340077 EALY(ph)ALTVLEMCMNHCGEKFHSEVAK ddPTM_HeLa_Curcumin_4h_R1 1 EALYALTVLEMCMNHCGEKFHSEVAK 26 1 H3BPI3;H3BMM6;Q9UJY4 H3BPI3 GGA2 ADP-ribosylation factor-binding protein GGA2 1 0 EALY(0.84)ALT(0.16)VLEMCMNHCGEKFHSEVAK 45.784 0.0092548 0 300.73 418.83 243.07 245.79 334.2 351.49 199.15 278.58 281.95 271.7 TRUE FALSE FALSE 276.9269032 455.0317989 252.078388 244.7729861 330.2148833 278.5870119 204.737613 363.5177596 251.0207904 281.1415548 0.985008792 1.618514913 0.896624436 0.870639654 1.174550249 0.990913677 0.728236753 1.293006151 0.892862639 1 8.1351529 -5.016347698 24.50223091 1.036340534 0.972859942 0 0.243286229 2698.274015 4044245.991 0.032224005 0.084856505 9.63E-06 5.016347698 -0.063480591 EAMEDGEIDGNK ddPTM_HeLa_Curcumin_4h_R1 1 EAMEDGEIDGNK 12 0 P19338;H7BY16 P19338 NCL Nucleolin 0 0 180.07 0.00085866 9522900 1858.8 1426.9 1427.5 1573.6 1799.1 2015.2 1548.4 1434 1392.2 1230 FALSE FALSE TRUE 1711.674019 1550.234878 1480.404406 1567.08886 1777.646908 1597.224804 1591.843937 1871.219999 1239.479143 1272.742408 1.344870735 1.218027205 1.163161058 1.231269462 1.39670596 1.254947422 1.250719648 1.4702268 0.973864888 1 10.31372475 -9.424205754 0.770050778 0.965896328 1.290233993 0.660576696 0.086974058 0.475736515 0.415601258 0.102110667 0.017208311 3.77E-10 9.424205754 0.324337665 EAMEDGEIDGNKVTLDWAKPK ddPTM_HeLa_Curcumin_4h_R1 1 EAMEDGEIDGNKVTLDWAKPK 21 2 P19338;H7BY16 P19338 NCL Nucleolin 0 0 74.812 0.00081482 40695000 3967.1 3002.5 3032.3 3516.1 3490.4 3503.4 3128.7 2582.7 3678.2 3172.6 FALSE FALSE TRUE 3653.099849 3262.022721 3144.679705 3501.55131 3448.77926 2776.755349 3216.482902 3370.153341 3274.710662 3282.847614 1.112783863 0.993656455 0.957912177 1.066620118 1.050545034 0.845837418 0.979784407 1.026594511 0.997521374 1 11.68073207 EANANGS(ph)SPEPVK ddPTM_HeLa_Curcumin_4h_R1 4 EANANGSSPEPVK 13 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 EANANGS(0.795)S(0.205)PEPVK;EANANGS(0.827)S(0.173)PEPVK;EANANGS(0.571)S(0.429)PEPVK;EANANGS(0.754)S(0.246)PEPVK ;;; 233.62 8.92E-20 800903000 25550.3 21970.6 23930.5 24482 25830.2 25848.4 21852.4 12669.8 23323.6 18752.4 TRUE FALSE FALSE 23527.96679 23869.64076 24817.38538 24380.69997 25522.19174 20487.15047 22465.51953 16532.7637 20765.05943 19404.0445 1.212529006 1.230137395 1.278980028 1.256475162 1.31530268 1.055818567 1.157775098 0.852026684 1.070140786 1 14.24406977 -2.922532804 9.19305819 1.133743092 0.707399544 0 0.138768248 22295093.59 0 0.020095325 0 0.001195273 2.922532804 -0.426343548 EANANGSS(ph)PEPVK ddPTM_HeLa_Curcumin_4h_R1 1 EANANGSSPEPVK 13 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 EANANGS(0.126)S(0.874)PEPVK 186.42 4.45E-05 11384000 3934.1 2869.2 3637.8 3613.3 3956.6 4345.9 3478 1684 3549.9 3252.5 TRUE FALSE FALSE 3622.711834 3117.200863 3772.620068 3598.349122 3909.420129 3444.511352 3575.583319 2197.443848 3160.484851 3365.524133 1.07641832 0.926215573 1.120960635 1.069179415 1.161608111 1.023469515 1.062414999 0.652927675 0.939076568 1 11.71661549 -4.259993079 24.86653213 1.046141799 0.652927537 0.734902576 0.070093444 39.6274471 681246.9685 0.008524003 0.071802564 5.50E-05 4.259993079 -0.393214262 EANANGSS(ph)PEPVKAVEAR ddPTM_HeLa_Curcumin_4h_R1 3 EANANGSSPEPVKAVEAR 18 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 EANANGS(0.018)S(0.982)PEPVKAVEAR;EANANGS(0.075)S(0.925)PEPVKAVEAR;EANANGS(0.106)S(0.894)PEPVKAVEAR ;; 112.56 0.00026989 463289000 9233.5 6544 6948.3 8220.8 5949.6 9593.5 5992.2 3909.76 11652.9 8620.7 TRUE FALSE FALSE 8502.658732 7109.634201 7205.81011 8186.784508 5878.654906 7603.699959 6160.325005 5101.827826 10374.60602 8920.268683 0.953184151 0.797020185 0.807801913 0.917773309 0.659022179 0.852407055 0.690598593 0.571936565 1.163037392 1 13.12287145 -3.086103467 0.195754861 1.040056671 3.30E-12 0.716475341 0.088902749 8.461148472 0.196764625 0.083801416 2.306045294 0.000820156 3.086103467 -1.040056671 EANMPLPGYK ddPTM_HeLa_Curcumin_4h_R1 4 EANMPLPGYK 10 0 P13797;A0A0A0MSQ0;P13797-2;U3KQI3 P13797 PLS3 Plastin-3 0 0 ;;; ;;; 140.11 7.44E-05 17168400 13401.3 11381.13 11356.93 11520.8 12393.81 15055.97 12672.9 11306.01 12132.77 11590.98 FALSE FALSE TRUE 12340.57296 12364.86416 11777.82782 11473.12998 12246.02191 11933.19211 13028.46747 14753.1604 10801.83549 11993.76569 1.028915628 1.030940947 0.981995823 0.956591139 1.021032278 0.994949577 1.086269967 1.230069086 0.900620853 1 13.54999707 -4.342787121 2.256085048 1.008253999 1.265154449 0.760623041 0.040748884 0.116493768 0.776509362 0.003466404 0.055059244 4.54E-05 4.342787121 0.256900449 EANNGSS(ph)PAGSLADAMSQK ddPTM_HeLa_Curcumin_4h_R1 2 EANNGSSPAGSLADAMSQK 19 0 C9J4I3;P51692 C9J4I3 STAT5B Signal transducer and activator of transcription 5B 1 0 EANNGS(0.2)S(0.568)PAGS(0.227)LADAMS(0.004)QK;EANNGS(0.037)S(0.863)PAGS(0.1)LADAMSQK ; 149.12 9.42E-05 26532400 5101.1 4954 3867 5013.4 4790.3 5388.1 4099.9 3426 4835 4343.8 TRUE FALSE FALSE 4697.342552 5382.201685 4010.314422 4992.655879 4733.178801 4270.547324 4214.93216 4470.571629 4304.612597 4494.746727 1.045073914 1.197442706 0.892222558 1.110775797 1.053046832 0.95011968 0.937746311 0.994621477 0.957698589 1 12.13402411 -5.256461029 24.54435101 1.034081446 0.958520866 0.162201975 0.078724007 427.8663611 2109456.175 0.010060427 0.024774683 5.54E-06 5.256461029 -0.07556058 EANQAINPK ddPTM_HeLa_Curcumin_4h_R1 2 EANQAINPK 9 0 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 0 ; ; 134.05 0.00038856 6227100 7459.6 6606 7137.2 7170.8 7640.9 7651.2 5822 5326.9 8044.2 7135.3 FALSE FALSE TRUE 6869.164789 7176.993204 7401.710911 7141.12913 7549.787258 6064.254873 5985.349651 6951.047288 7161.771386 7383.251144 0.930371276 0.972064076 1.002500222 0.967206586 1.022555932 0.821352918 0.810665862 0.94146158 0.970002408 1 12.85004052 -5.256147455 24.99961951 0.972719891 0.85311069 0.653099458 0.040696836 219.6767789 1037772.196 0.006084051 0.015023586 5.54E-06 5.256147455 -0.119609201 EANQQQQFNR ddPTM_HeLa_Curcumin_4h_R1 2 EANQQQQFNR 10 0 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 ; ; 185.6 4.21E-16 1770340 445.93 348.55 538.58 477.55 602.58 425.32 555.47 415.53 387.44 288.48 FALSE FALSE TRUE 410.63417 378.6771089 558.5402486 475.5740246 595.3946271 337.1038377 571.0549932 542.2231841 344.9388013 298.5046585 1.375637392 1.268580232 1.87112741 1.593187949 1.994590738 1.129308465 1.913052198 1.816464731 1.15555584 1 8.221609636 -7.74212739 0.407995446 0.97855061 1.763569257 0.483166694 0.252694576 0.570856573 0.255759513 0.169972914 0.126207458 1.81E-08 7.74212739 0.785018647 KS(ph)T(ph)YPPSGPTY(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 KSTYPPSGPTYR 12 1 A0A1B0GV88;A0A1B0GV95;A0A1B0GUH5;A0A1B0GTZ5;A0A1B0GTM3;A0A1B0GUA4;A0A1B0GW68;E7EMM4;A0A1B0GUG1;A0A1B0GVG2;A0A1B0GTP7;A0A1B0GUB3;A0A1B0GU06;A0A1B0GVC9;A0A1B0GU62;A0A1B0GVJ1;A0A1B0GW48;Q13510;Q13510-2 A0A1B0GV88 ASAH1 Acid ceramidase;Acid ceramidase subunit alpha;Acid ceramidase subunit beta 3 0 KS(0.665)T(0.668)Y(0.664)PPS(0.019)GPT(0.042)Y(0.942)R 61.11 0.008378 0 972.32 971.87 1088.7 1258.5 1198.4 1682.4 2306.8 3413.8 1446.3 1506.3 TRUE FALSE FALSE 895.359846 1055.874112 1129.04818 1253.29266 1184.109863 1333.451275 2371.5226 4454.651905 1287.644508 1558.643813 0.574448016 0.677431305 0.724378572 0.804091769 0.759705234 0.855520206 1.521529537 2.858030724 0.826131344 1 10.60607556 -4.279515744 1.744070907 0.775342605 3.528992477 0.973383095 0.105686666 0.144454584 0.440434404 0.023300474 0.650017624 5.25E-05 4.279515744 2.753649872 up EAPAEGEAAEPGSPTAAEGEAASAAS(ph)STSSPK ddPTM_HeLa_Curcumin_4h_R1 1 EAPAEGEAAEPGSPTAAEGEAASAASSTSSPK 32 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 EAPAEGEAAEPGSPTAAEGEAAS(0.026)AAS(0.688)S(0.205)T(0.062)S(0.014)S(0.004)PK 128.99 2.45E-13 4515300 1528.4 1282.1 1278.5 1473.6 1706 2055.4 1716.7 1448.7 1709.8 1457.3 TRUE FALSE FALSE 1407.425527 1392.919011 1325.882335 1467.502634 1685.657064 1629.086871 1764.865982 1890.401961 1522.239218 1507.941067 0.933342528 0.923722446 0.87926668 0.973183015 1.117853411 1.080338554 1.170381271 1.253631195 1.009481903 1 10.55836433 -5.115216899 1.003599667 0.957123616 1.244685386 0.813714706 0.04877503 0.247270796 0.387592146 0.008415681 0.055181694 7.67E-06 5.115216899 0.287561769 EAPAQPAPEK ddPTM_HeLa_Curcumin_4h_R1 1 EAPAQPAPEK 10 0 K7EMT0;Q15428 K7EMT0 SF3A2 Splicing factor 3A subunit 2 0 0 106.29 0.0064778 1748700 1854.3 1583.4 1897.2 1629.7 1691.7 2036.8 2150.4 1724.7 1910.9 1874.8 FALSE FALSE TRUE 1707.530198 1720.262041 1967.511901 1622.956733 1671.527582 1614.344721 2210.734436 2250.55309 1701.279051 1939.94916 0.880193272 0.886756249 1.014207971 0.83659756 0.861634736 0.832158261 1.139583697 1.160109314 0.876970946 1 10.92180313 -4.743512458 23.56078862 0.923870367 1.149847049 0.708005961 0.062891089 61.15541593 80371.74905 0.009893232 0.036819886 1.81E-05 4.743512458 0.225976682 EAPATGPS(ph)PQHPQK ddPTM_HeLa_Curcumin_4h_R1 1 EAPATGPSPQHPQK 14 0 H0YCU2;Q9H0F6 H0YCU2 SHARPIN Sharpin 1 0 EAPAT(0.416)GPS(0.584)PQHPQK 67.418 0.017433 2752800 2887.4 2883.7 3365 3281.8 3539.1 3805.8 3247.3 3006 3241.5 3028.9 TRUE FALSE FALSE 2658.859243 3132.954178 3489.70986 3268.220781 3496.898544 3016.43418 3338.410498 3922.515562 2885.91556 3134.15405 0.84834989 0.999617163 1.113445544 1.04277605 1.115739204 0.962439667 1.065171158 1.251538852 0.920795696 1 11.61386038 -6.975213642 5.048419702 0.927995186 1.082645658 0.494987966 0.076559739 0.136833012 9.311614164 0.014041413 0.018287016 1.06E-07 6.975213642 0.154650472 EAPGPAGGGGGGSR ddPTM_HeLa_Curcumin_4h_R1 2 EAPGPAGGGGGGSR 14 0 Q9BQ61;K7ELS0;K7ERU7;K7EN60 Q9BQ61 C19orf43 Uncharacterized protein C19orf43 0 0 ; ; 101.35 0.0056224 1597130 254.35 165.37 170.81 365.473 53.184 178.23 0 0 330.68 187.26 FALSE FALSE TRUE 234.2179291 179.6638459 177.1403689 363.9607696 52.54981554 141.2630889 0 0 294.4052313 193.7672711 1.208758981 0.927214616 0.91419138 1.878339761 0.271200679 0.729034827 0 0 1.519375433 1 7.598181098 -5.15333628 1.412908294 1.109231657 4.99E-10 0.594174907 0.37478599 0.22631014 0.812916076 0.049012521 0.21891188 7.03E-06 5.15333628 -1.109231656 EAPGS(ph)PPLS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 EAPGSPPLSPR 11 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;E9PNR0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 2 0 EAPGS(1)PPLS(1)PR 105.19 0.020258 49299000 4176.8 3728.1 4213.5 3992.4 4113 4495.5 2831.9 2242.5 3905 3578.1 TRUE FALSE FALSE 3846.201873 4050.340352 4369.656017 3975.880507 4063.955161 3563.082625 2911.355492 2926.227927 3476.63127 3702.438709 1.038829316 1.093965537 1.180210224 1.07385451 1.097642792 0.962361002 0.786334554 0.790351484 0.939011161 1 11.85426014 -4.874958183 3.296084338 1.045648383 0.784166726 0.750634465 0.06164746 0.09075208 1.914405332 0.008901301 0.031988081 1.33E-05 4.874958183 -0.261481657 EAPGS(ph)PPLSPR ddPTM_HeLa_Curcumin_4h_R1 1 EAPGSPPLSPR 11 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;E9PNR0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 0 EAPGS(0.97)PPLS(0.03)PR 91.202 0.016459 87866000 2827.9 2670.6 2058.3 2631.5 2868.2 3675.3 3839 2564.3 3019 2540.5 TRUE FALSE FALSE 2604.068731 2901.434764 2134.582409 2620.61155 2833.998588 2913.001351 3946.712008 3346.143265 2687.823253 2628.782186 0.990598896 1.103718208 0.812004289 0.996891855 1.078065198 1.108118187 1.501346148 1.272887226 1.022459475 1 11.36017889 -4.93322159 3.743437164 0.996493108 1.38577019 0.736765351 0.09059408 0.073412173 2.060983981 0.011768004 0.038801379 1.17E-05 4.93322159 0.389277082 EAPPMEK(ac)PEVVK ddPTM_HeLa_Curcumin_4h_R1 3 EAPPMEKPEVVK 12 1 S4R456;K7EM56;A0A0B4J2B4;K7EJ78;S4R417;K7EQJ5;K7ELC2;P62841 S4R456 RPS15 40S ribosomal protein S15 0 1 ;; EAPPMEK(1)PEVVK;EAPPMEK(1)PEVVK;EAPPMEK(1)PEVVK 125.28 0.00070417 12123000 3355.45 4126.04 3247.82 2967.77 6091.41 7871.2 5796.32 5377.76 7988.69 3267.57 FALSE TRUE FALSE 3089.862592 4482.676512 3368.187066 2955.490154 6018.773914 6238.624393 5958.949139 7017.414268 7112.350694 3381.117814 0.913858304 1.325797194 0.9961756 0.874116288 1.780113632 1.845136649 1.762419846 2.075471679 2.103550093 1 11.72328457 -5.72601118 6.560795147 0.986514191 1.863492365 0.350801004 0.379712019 0.040118776 4.90344948 0.020384143 0.040494499 1.88E-06 5.72601118 0.876978175 EAPPMEKPEVVK ddPTM_HeLa_Curcumin_4h_R1 2 EAPPMEKPEVVK 12 1 S4R456;K7EM56;A0A0B4J2B4;K7EJ78;S4R417;K7EQJ5;K7ELC2;P62841 S4R456 RPS15 40S ribosomal protein S15 0 0 ; ; 107.34 0.0020499 15754500 11235.9 8892.4 10120.8 9775.9 9868.5 12932 9748.9 10826.8 10900.9 10424.9 FALSE FALSE TRUE 10346.56666 9661.019432 10495.88575 9735.449916 9750.824583 10249.75743 10022.4279 14127.84148 9705.098543 10787.1645 0.959155361 0.895603236 0.972997654 0.902503148 0.903928422 0.950180877 0.929106801 1.309690001 0.899689491 1 13.39702807 -4.258444575 24.97850864 0.959216169 1.30969013 0.878801478 0.040871264 75.4280689 629083.4321 0.006029146 0.056563941 5.52E-05 4.258444575 0.350473961 EAPPPVLLT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 EAPPPVLLTPK 11 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 0 EAPPPVLLT(1)PK;EAPPPVLLT(1)PK;EAPPPVLLT(1)PK ;; 134.61 0.0062445 39537600 14979.7 13231.8 13386.7 13677.3 13820.9 22305.4 20511.9 9995.2 17053.8 12141.7 TRUE FALSE FALSE 13794.04094 14375.49783 13882.82288 13620.70696 13656.09479 17679.00861 21087.40871 13042.69047 15183.04081 12563.62317 1.097934947 1.144215935 1.105001534 1.08413845 1.086955141 1.407158458 1.678449634 1.038131301 1.208492216 1 13.61696496 -5.273849952 6.029503341 1.064089053 1.406234421 0.36449036 0.156343186 0.088413688 13.79438322 0.019626207 0.046552682 5.32E-06 5.273849952 0.342145368 QIS(ph)QDVK ddPTM_HeLa_Curcumin_4h_R1 1 QISQDVK 7 0 E9PIJ1;A0A590UK85;A0A590UJY6;A0A5F9UK94;H0Y360;Q01433-3;Q01433-5;Q01433-2;Q01433-4;Q01433;E9PJF6 E9PIJ1 AMPD2 AMP deaminase 2 1 0 QIS(1)QDVK 99.343 0.020124 68240000 6484.8 5373.8 6297.1 6601.7 6509.8 7847 9597.4 13179 6191.4 6042.7 TRUE FALSE FALSE 5971.521237 5838.287327 6530.476065 6574.383915 6432.174887 6219.443746 9866.677214 17197.21643 5512.21891 6252.683375 0.955033364 0.933725087 1.044427756 1.051449997 1.028706317 0.994683942 1.57799086 2.750373783 0.88157653 1 12.61025975 -4.279166234 1.88056636 0.985831271 3.272980063 0.989409044 0.055723561 0.044990658 0.166616195 0.006825783 0.177384527 5.26E-05 4.279166234 2.287148792 up DSGRGDS(ph)VSDSGSDALR ddPTM_HeLa_Curcumin_4h_R1 2 DSGRGDSVSDSGSDALR 17 1 Q53EL6;Q53EL6-2;Q5VZS7 Q53EL6 PDCD4 Programmed cell death protein 4 1 0 DSGRGDS(0.948)VS(0.026)DS(0.026)GSDALR;DSGRGDS(0.635)VS(0.249)DS(0.013)GS(0.103)DALR ; 213.64 2.12E-14 85964000 5821.2 4480.5 4595 4587.3 4487.8 4383.5 1741.47 1353.11 5727.5 5452.6 TRUE FALSE FALSE 5360.445877 4867.774455 4765.294742 4568.318968 4434.285916 3474.312688 1790.330961 1765.66701 5099.207579 5642.077444 0.950083711 0.862762786 0.844599315 0.809687391 0.785931416 0.615786069 0.317317686 0.312946256 0.903781919 1 12.46201075 -4.746532435 0.553995235 0.977222911 4.85E-17 0.942956439 0.055910575 0.332303598 0.094978236 0.010546389 0.187937088 1.79E-05 4.746532435 -0.977222911 down TVSGPGTPEPRPAT(ph)PGASSVEQLR ddPTM_HeLa_Curcumin_4h_R1 1 TVSGPGTPEPRPATPGASSVEQLR 24 1 Q9H3U1 Q9H3U1 UNC45A Protein unc-45 homolog A 1 0 TVSGPGTPEPRPAT(0.676)PGAS(0.162)S(0.162)VEQLR 82.362 0.00017164 35860000 1548.4 1193.5 1396.1 1541.5 1208.7 1464.6 682.61 397.54 1450.6 1182.3 TRUE FALSE FALSE 1425.842506 1296.660822 1447.840694 1535.121681 1194.287042 1160.825451 701.7621994 518.748116 1291.472809 1223.384837 1.165489765 1.059896104 1.183471178 1.25481503 0.976215338 0.94886369 0.573623424 0.424026929 1.0556554 1 10.25666258 -4.744404036 1.680011797 1.095925064 0.38921784 0.902720306 0.078692934 0.113370255 0.540755478 0.013405476 0.095935609 1.80E-05 4.744404036 -0.706707223 down EAQDDLVK ddPTM_HeLa_Curcumin_4h_R1 1 EAQDDLVK 8 0 E7EQR4;P15311 E7EQR4 EZR Ezrin 0 0 115.71 0.003328 2626200 2199.2 1793.4 1737.2 1925.8 2290.1 3030.5 2162.2 2509.6 2441.3 1862.4 FALSE FALSE TRUE 2025.130999 1948.413505 1801.58216 1917.83155 2262.792053 2401.940139 2222.865513 3274.765487 2173.495498 1927.118261 1.050859742 1.011050304 0.934858123 0.995181037 1.174184324 1.24638959 1.153466062 1.699306967 1.127847492 1 10.91222939 -1 0.68479853 1.01852182 74.12404358 0.845628643 0.081744759 58.84425611 0.309093241 0.012232998 6579.343668 0.1 1 73.10552176 EAQMAAK(ac)LER ddPTM_HeLa_Curcumin_4h_R1 1 EAQMAAKLER 10 1 P16949;P16949-2 P16949 STMN1 Stathmin 0 1 EAQMAAK(1)LER 110.08 0.0052424 13009000 2449.5 2021.9 2253.5 2479.7 2202.9 2920.2 2226.2 2912.4 2857.6 2346.1 FALSE TRUE FALSE 2255.61949 2196.664027 2337.016692 2469.439658 2176.631856 2314.517603 2288.66118 3800.377353 2544.128429 2427.6268 0.929145901 0.904860676 0.962675438 1.017223759 0.896608925 0.953407502 0.942756597 1.565470175 1.047989925 1 11.24533094 -4.260555356 24.99259075 0.958200015 1.565470366 0.939682863 0.045888408 10.65517758 301187.2025 0.005587469 0.045308575 5.49E-05 4.260555356 0.607270351 EAQQKVPDEEENEES(ph)DNEKETEK ddPTM_HeLa_Curcumin_4h_R1 4 EAQQKVPDEEENEESDNEKETEK 23 2 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 EAQQKVPDEEENEES(1)DNEKETEK;EAQQKVPDEEENEES(1)DNEKETEK;EAQQKVPDEEENEES(0.999)DNEKET(0.001)EK;EAQQKVPDEEENEES(0.998)DNEKET(0.002)EK ;;; 110.38 9.99E-06 251355000 10978.9 6110.9 10593.2 12739.8 10614.7 8543.3 8913 6749.7 11590.9 9435.5 TRUE FALSE FALSE 10109.90848 6639.098966 10985.79331 12687.08608 10488.12664 6771.323277 9163.074792 8807.652458 10319.40727 9763.382923 1.035492366 0.679999854 1.125203569 1.299455955 1.074230799 0.693542733 0.938514331 0.902110726 1.056949968 1 13.2531654 -5.28845742 24.96042544 1.02461909 0.854101713 0.240938011 0.156158721 856.7563032 791507.0147 0.02253886 0.050410529 5.15E-06 5.28845742 -0.170517376 S(ph)GAQASSTPLSPTR ddPTM_HeLa_Curcumin_4h_R1 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 S(1)GAQASSTPLSPTR 173.77 0.00019355 64243000 584.28 507.65 532.75 656.4 570.32 572.58 364.21 197.54 588.4 577.13 TRUE FALSE FALSE 538.0336215 551.529004 552.4941837 653.6839907 563.5193065 453.8204537 374.4287524 257.7690366 523.8539921 597.1852245 0.900949319 0.923547639 0.925163854 1.094608446 0.943625668 0.759932488 0.626989311 0.431640011 0.877205213 1 9.222034661 -4.74355244 1.492823451 0.958540701 0.422339352 0.886287818 0.062026747 0.126023321 0.445362262 0.009396551 0.076488601 1.80E-05 4.74355244 -0.53620135 down EAQTLDSQIQETS(ph)I ddPTM_HeLa_Curcumin_4h_R1 2 EAQTLDSQIQETSI 14 0 E7EVA0;P27816;P27816-2;P27816-4 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 EAQTLDSQIQET(0.112)S(0.888)I;EAQTLDSQIQET(0.061)S(0.939)I ; 229.97 1.86E-20 191012000 10678.7 8772.1 8536.4 10060.6 9043.3 12781.9 9831.1 10296.3 11562.6 9613.1 TRUE FALSE FALSE 9833.469627 9530.321236 8852.766493 10018.9719 8935.464554 10130.78986 10106.93421 13435.59447 10294.21171 9947.154509 0.988571115 0.958095225 0.889979791 1.007219893 0.898293532 1.018461093 1.016062855 1.350697273 1.034890098 1 13.28006817 -4.226852063 2.96157188 0.980057321 1.430759535 0.856066323 0.045929041 0.117364664 1.365597493 0.00596191 0.12982337 5.93E-05 4.226852063 0.450702214 EAS(ph)AESDVGK ddPTM_HeLa_Curcumin_4h_R1 2 EASAESDVGK 10 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 0 EAS(0.998)AES(0.002)DVGK;EAS(1)AESDVGK ; 155.47 0.0006407 21334000 7065.9 4827.6 5046.6 5014.7 5701.2 7641 3569 6282.9 4317.5 4052.5 TRUE FALSE FALSE 6506.626559 5244.876233 5233.631435 4993.9505 5633.216914 6056.170468 3669.136535 8198.527287 3843.881052 4193.324073 1.551663178 1.250768159 1.248086564 1.190928822 1.343377429 1.44424098 0.874994746 1.955138011 0.916666822 1 12.03387862 -9.558664703 1.331902206 1.000057751 1.359167471 0.2619413 0.264066742 0.529530571 1.683732371 0.170421863 0.040210914 2.76E-10 9.558664703 0.35910972 EAS(ph)LGEASK ddPTM_HeLa_Curcumin_4h_R1 2 EASLGEASK 9 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 EAS(1)LGEASK;EAS(1)LGEASK ; 112.13 0.0084624 20260200 4921.1 4854.8 5135.8 5086.2 6165 7598.9 5584.8 4650.5 5448.7 4473.9 TRUE FALSE FALSE 4531.589742 5274.427279 5326.137266 5065.154652 6091.486401 6022.802483 5741.494457 6068.416042 4850.991242 4629.367692 0.978878768 1.139340755 1.150510744 1.094135309 1.315835511 1.300998945 1.240232973 1.310852031 1.047873395 1 12.17659944 -6.417958849 0.7700564 0.986688243 1.297565705 0.795636736 0.055208627 0.163550808 0.19285854 0.010802219 0.022937763 3.82E-07 6.417958849 0.310877462 EAS(ph)PAPLAQGEPGR ddPTM_HeLa_Curcumin_4h_R1 2 EASPAPLAQGEPGR 14 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 0 EAS(1)PAPLAQGEPGR;EAS(1)PAPLAQGEPGR ; 130.47 0.0010768 13373400 1959.65 1648.4 1803.73 1533.88 1995.43 2007.64 1814.4 720.31 1775.6 1576.14 TRUE FALSE FALSE 1804.541635 1790.880351 1870.577821 1527.533211 1971.635801 1591.232833 1865.307181 939.9292031 1580.821122 1630.910748 1.106462532 1.098086056 1.146952905 0.936613615 1.208917044 0.975671315 1.14372119 0.576321668 0.969287329 1 10.67146212 -4.255656673 24.94554426 1.063540883 0.576321452 0.743126846 0.086202725 211.6042581 912794.7146 0.01051815 0.125822417 5.55E-05 4.255656673 -0.48721943 EAS(ph)PAPLAQGEPGREDLPTR ddPTM_HeLa_Curcumin_4h_R1 2 EASPAPLAQGEPGREDLPTR 20 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 0 EAS(0.974)PAPLAQGEPGREDLPT(0.026)R;EAS(0.999)PAPLAQGEPGREDLPT(0.001)R ; 85.062 0.00085362 232820000 3750.4 3610.9 3813.1 3456.2 3793.3 4259.5 3160.2 1709.14 3376.3 3023.3 TRUE FALSE FALSE 3453.551883 3923.010106 3954.41684 3441.89916 3748.067375 3376.031686 3248.866707 2230.248918 3005.928337 3128.35945 1.10394983 1.254015138 1.2640545 1.100224963 1.198093581 1.079170006 1.038520911 0.712913255 0.960864116 1 11.61119057 -4.237562482 2.720863293 1.095722762 0.62580956 0.610819487 0.095709746 0.300153185 2.80062893 0.014790436 0.323928591 5.79E-05 4.237562482 -0.469913201 EAS(ph)PSTLNDK ddPTM_HeLa_Curcumin_4h_R1 2 EASPSTLNDK 10 0 P54253 P54253 ATXN1 Ataxin-1 1 0 EAS(0.815)PS(0.184)T(0.002)LNDK;EAS(0.982)PS(0.018)TLNDK ; 155.99 0.00063775 131318000 8477.9 6572.1 7244.8 7636.7 7219.1 7459.8 6243.1 3212.2 7502.6 6540.8 TRUE FALSE FALSE 7806.865269 7140.163039 7513.298661 7605.101359 7133.016947 5912.553391 6418.264584 4191.584993 6679.583551 6768.092313 1.153480908 1.054974239 1.110105819 1.123669862 1.053918389 0.873592309 0.948312211 0.619315577 0.986922643 1 12.72453353 -3.788662078 0.821025294 1.078735329 1.77E-16 0.794107614 0.0673136 1.584337735 0.45641668 0.011601586 1.863853423 0.000162681 3.788662078 -1.078735329 EASDPQPEEADGGLK ddPTM_HeLa_Curcumin_4h_R1 1 EASDPQPEEADGGLK 15 0 P52907 P52907 CAPZA1 F-actin-capping protein subunit alpha-1 0 0 153.75 0.0028579 4804400 2861.8 2280 2831 2667 2893.2 4948.6 3361.6 2668.3 2918.4 2616.7 FALSE FALSE TRUE 2635.28551 2477.073041 2935.91935 2655.964661 2858.70048 3922.204578 3455.917449 3481.852387 2598.258821 2707.63013 0.973281203 0.914849119 1.084313296 0.980918565 1.055794308 1.448574727 1.276362458 1.285940922 0.95960626 1 11.40281496 -5.392240072 5.033609975 0.989789991 1.329048142 0.874003352 0.059773646 0.051534438 1.893057312 0.00799058 0.018220858 4.05E-06 5.392240072 0.339258151 LTLT(ph)SDESTLIEDGGAR ddPTM_HeLa_Curcumin_4h_R1 2 LTLTSDESTLIEDGGAR 17 0 Q9NRX5 Q9NRX5 SERINC1 Serine incorporator 1 1 0 LT(0.024)LT(0.436)S(0.436)DES(0.086)T(0.017)LIEDGGAR;LT(0.116)LT(0.442)S(0.442)DESTLIEDGGAR ; 207.21 2.30E-10 25868000 3543.22 2965.47 3604.55 3423.57 3539.81 3345.03 2177.56 1173.68 4094.21 3386.76 TRUE FALSE FALSE 3262.770398 3221.792013 3738.137794 3409.404174 3497.600078 2651.233072 2238.656473 1531.529629 3645.085406 3504.449658 0.931036458 0.919343214 1.066683262 0.972878628 0.998045462 0.756533359 0.638804004 0.437024292 1.040130623 1 11.77497218 -4.742028376 1.429344826 0.973958712 0.421996849 0.925432804 0.052603865 0.105183584 0.331880779 0.007508276 0.064291841 1.81E-05 4.742028376 -0.551961863 down EASRPPEEPSAPS(ph)PTLPAQFK ddPTM_HeLa_Curcumin_4h_R1 2 EASRPPEEPSAPSPTLPAQFK 21 1 H0Y3X6;A0A0C4DFX9;Q9H3P2;Q9H3P2-7 H0Y3X6 NELFA Negative elongation factor A 1 0 EAS(0.008)RPPEEPS(0.121)APS(0.839)PT(0.031)LPAQFK;EASRPPEEPS(0.001)APS(0.974)PT(0.024)LPAQFK ; 84.602 0.00038106 15249400 2974.2 2695.3 2513.89 2551.3 2592.71 3388.8 2811.1 2406.51 3019.1 2479.84 TRUE FALSE FALSE 2738.788932 2928.269722 2607.056975 2540.743397 2561.793627 2685.92468 2889.9719 3140.243821 2687.912283 2566.014255 1.067331924 1.141174378 1.015994736 0.990151708 0.998355181 1.046730226 1.126249355 1.223782687 1.047504813 1 11.32531347 -4.481926916 2.124139354 1.034115515 1.235731443 0.662314995 0.041934927 0.221660854 1.520748785 0.006755238 0.070993569 3.30E-05 4.481926916 0.201615928 EASRPPEEPSAPSPT(ph)LPAQFK ddPTM_HeLa_Curcumin_4h_R1 3 EASRPPEEPSAPSPTLPAQFK 21 1 H0Y3X6;A0A0C4DFX9;Q9H3P2;Q9H3P2-7 H0Y3X6 NELFA Negative elongation factor A 1 0 EASRPPEEPS(0.003)APS(0.385)PT(0.612)LPAQFK;EASRPPEEPS(0.006)APS(0.318)PT(0.675)LPAQFK;EASRPPEEPS(0.002)APS(0.478)PT(0.52)LPAQFK ;; 110.89 2.91E-05 250254000 6958.9 6434.5 6532 6481 6446 7681.9 7416 7791.3 7903.7 6001.3 TRUE FALSE FALSE 6408.095722 6990.669508 6774.081666 6454.183339 6369.13566 6088.587347 7624.073001 10166.8315 7036.683884 6209.844728 1.031925274 1.125739824 1.090861682 1.039346976 1.025651355 0.980473363 1.227739716 1.637211871 1.133149731 1 12.60034148 -4.333693619 2.410392094 1.02938806 1.726513514 0.912347167 0.054297684 0.076225467 0.597353895 0.00676468 0.102453684 4.64E-05 4.333693619 0.697125454 EASRSS(ph)PVEFECINEK ddPTM_HeLa_Curcumin_4h_R1 1 EASRSSPVEFECINEK 16 1 H0YB26;O75131 H0YB26 CPNE3 Copine-3 1 0 EAS(0.178)RS(0.178)S(0.645)PVEFECINEK 57.973 0.01975 9274400 1323.4 952.97 1248 1047.8 1258.3 1569.9 904.02 971.21 1213.2 1228.4 TRUE FALSE FALSE 1218.651494 1035.34048 1294.251978 1043.464481 1243.295594 1244.285044 929.3843682 1267.327458 1080.114995 1271.086809 0.958747652 0.814531685 1.018224695 0.820923067 0.978135864 0.978914292 0.73117301 0.997042412 0.849757065 1 10.31184685 -7.489875949 10.75708585 0.981849309 0.9041899 0 0.097653685 0.850278835 273.7363135 0.013990412 0.015524368 3.24E-08 7.489875949 -0.077659409 EASSS(ph)SPEAGEGQIR ddPTM_HeLa_Curcumin_4h_R1 1 EASSSSPEAGEGQIR 15 0 J3QSS7;Q86U28-2;Q86U28 J3QSS7 ISCA2 "Iron-sulfur cluster assembly 2 homolog, mitochondrial" 1 0 EAS(0.017)S(0.012)S(0.572)S(0.399)PEAGEGQIR 125.73 0.00089227 5444700 1523.2 1137.2 1425.4 1215.4 1087.7 1989.1 905.68 859.32 1330.2 1387.2 TRUE FALSE FALSE 1402.637113 1235.494501 1478.226578 1210.370997 1074.729888 1576.538238 931.0909433 1121.322712 1184.280388 1435.405097 0.977171612 0.860728796 1.029832332 0.843226069 0.748729324 1.098322865 0.648660748 0.781189028 0.825049591 1 10.48724223 -2.090975313 0.237070427 1.010053219 8.58E-17 0.111587547 0.126174801 22.94386869 0.443772939 0.068168042 8.238123834 0.008110072 2.090975313 -1.010053219 EASTTAAAPGEETS(ph)PVQVPAR ddPTM_HeLa_Curcumin_4h_R1 2 EASTTAAAPGEETSPVQVPAR 21 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 0 EASTTAAAPGEET(0.09)S(0.91)PVQVPAR;EASTTAAAPGEET(0.012)S(0.988)PVQVPAR ; 192.22 7.29E-13 51431000 7376.8 6016.7 6139.3 6842.5 6739 8144.3 5335 3025.9 7617.9 6613.4 TRUE FALSE FALSE 6792.918496 6536.756738 6366.827859 6814.187548 6658.641826 6455.080375 5484.685742 3948.48298 6782.235429 6843.215158 0.992650142 0.955217188 0.930385457 0.995758191 0.973028273 0.943281809 0.801477904 0.576992377 0.991089024 1 12.74045859 -4.260462662 1.309967268 0.987921583 0.389451301 0.96989245 0.02185975 0.16846169 0.243872561 0.003618019 0.134487576 5.49E-05 4.260462662 -0.598470282 EAT(ph)GLSPQAAQEK ddPTM_HeLa_Curcumin_4h_R1 1 EATGLSPQAAQEK 13 0 C9JRM9;P17029 C9JRM9 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 0 EAT(0.658)GLS(0.342)PQAAQEK 119.62 0.00737 28460000 4979.7 3243.3 4601.7 4659.8 5276.3 5620.1 3934.8 2490.4 4683.8 3657.5 TRUE FALSE FALSE 4585.55149 3523.6364 4772.24305 4640.518982 5213.383569 4454.427908 4045.199898 3249.711496 4169.998858 3784.597853 1.211635072 0.931046451 1.260964371 1.22615907 1.37752643 1.176988436 1.068858583 0.858667584 1.101834071 1 11.88592429 -4.307527778 3.136062656 1.134121872 0.831093604 0.339139466 0.123402641 0.330717865 5.123234005 0.019462738 0.230292348 4.93E-05 4.307527778 -0.303028267 EAT(ph)QARS(ph)RARGR ddPTM_HeLa_Curcumin_4h_R1 1 EATQARSRARGR 12 3 Q86SI9-2 Q86SI9-2 2 0 EAT(1)QARS(1)RARGR 118.76 0.0055872 17768000 116.11 148.57 0 173.81 115.06 133.93 136.06 0 162.59 125.36 TRUE FALSE FALSE 106.919771 161.4117288 0 173.0908203 113.6879846 106.1514083 139.8774774 0 144.7542838 129.7162507 0.824258876 1.244344698 0 1.334380383 0.876435944 0.818335465 1.078334262 0 1.115930217 1 7.019215419 -4.254471509 24.55620073 0.902760811 5.37E-07 0.38456304 0.348949574 466.0397903 1642364.917 0.041737289 0.551152454 5.57E-05 4.254471509 -0.902760273 EATAGNPGGQTVR ddPTM_HeLa_Curcumin_4h_R1 1 EATAGNPGGQTVR 13 0 P27708;F8VPD4 P27708 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 0 0 107.97 0.0027176 520060 270.26 239.37 143.68 153.72 171.31 168.84 174.82 219.01 0 158.36 FALSE FALSE TRUE 248.8686358 260.0600762 149.0049072 153.0839474 169.2672401 133.8206808 179.7249787 285.7851408 0 163.8629982 1.518760419 1.587057963 0.909326137 0.934219128 1.032980246 0.816661981 1.096800258 1.74404926 0 1 7.356346307 -6.729820429 24.99984942 1.277471844 1.067398837 0 0.492796795 387.8655413 306669.0871 0.050606064 0.071564204 1.86E-07 6.729820429 -0.210073007 EATAQKPTGSVGSTVT(ph)TPPPLVR ddPTM_HeLa_Curcumin_4h_R1 3 EATAQKPTGSVGSTVTTPPPLVR 23 1 Q86YP4-2;Q86YP4;Q86YP4-3 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 0 EATAQKPTGSVGS(0.025)T(0.086)VT(0.444)T(0.444)PPPLVR;EATAQKPTGSVGS(0.002)T(0.007)VT(0.496)T(0.496)PPPLVR;EATAQKPTGSVGS(0.001)T(0.003)VT(0.498)T(0.498)PPPLVR ;; 98.067 7.21E-05 152491000 3816.01 3626.55 3538.6 3736.68 3859.7 5065 4452.93 3663.58 4572 4119.9 TRUE FALSE FALSE 3513.968782 3940.012822 3669.743629 3721.218608 3813.675598 4014.461906 4577.867231 4780.588677 4070.463039 4263.066218 0.824282008 0.924220413 0.860822573 0.87289721 0.894585119 0.941684154 1.073843801 1.121396768 0.954820505 1 12.05767575 -4.743856367 2.675932779 0.906811008 1.116286423 0.731884677 0.046499778 0.151659953 2.114276365 0.009485599 0.044825173 1.80E-05 4.743856367 0.209475416 EATAQKPTGSVGSTVTT(ph)PPPLVR ddPTM_HeLa_Curcumin_4h_R1 1 EATAQKPTGSVGSTVTTPPPLVR 23 1 Q86YP4-2;Q86YP4;Q86YP4-3 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 0 EATAQKPT(0.001)GS(0.001)VGS(0.016)T(0.006)VT(0.18)T(0.796)PPPLVR 84.113 0.00033422 40791000 2302.3 1776.4 2174.5 2171.7 2341.2 2956.7 2210.3 1881.4 2163.4 2070.8 TRUE FALSE FALSE 2120.070526 1929.944101 2255.088883 2162.714081 2313.282719 2343.447091 2272.315069 2455.030199 1926.080433 2142.760146 0.989411031 0.90068135 1.05242245 1.009312258 1.079580803 1.093658147 1.060461701 1.145732621 0.898878223 1 11.06525465 -5.811884467 1.337362638 0.989270932 1.100703973 0.594957638 0.048359821 0.210797817 0.753236404 0.005956485 0.014959928 1.54E-06 5.811884467 0.111433041 EATDAIGHLDR ddPTM_HeLa_Curcumin_4h_R1 4 EATDAIGHLDR 11 0 Q12906;Q12906-7;Q12906-5;Q12906-4;Q12906-2;Q12906-6;Q12906-3 Q12906 ILF3 Interleukin enhancer-binding factor 3 0 0 ;;; ;;; 149.23 0.00055296 40390600 30720.5 26835.1 27864.2 29280.7 29925.7 35832.4 28800.8 23369.7 29531.2 26159.5 FALSE FALSE TRUE 28288.94001 29154.60647 28896.87176 29159.54422 29568.85557 28400.35633 29608.87293 30495.01395 26291.70124 27068.54068 1.045085524 1.07706606 1.067544501 1.077248477 1.092369771 1.049201605 1.093848142 1.126585076 0.971301023 1 14.72432949 -13.52287875 0.037161804 0.541139881 1.352831161 0.821463782 0.018456289 219.8005274 0.653233667 11.94426484 4.198563479 3.00E-14 13.52287875 0.81169128 EATFSNPK ddPTM_HeLa_Curcumin_4h_R1 1 EATFSNPK 8 0 O75534-2;O75534;O75534-3;O75534-4;E9PLT0 O75534-2 CSDE1 Cold shock domain-containing protein E1 0 0 100.15 0.013281 4193100 1518.3 1040.4 1308.6 1095.1 1404.9 1583.2 1062.3 980.74 1310.8 1395.6 FALSE FALSE TRUE 1398.124953 1130.32754 1357.097867 1090.568766 1388.147485 1254.826474 1092.105279 1279.763111 1167.008519 1444.096996 0.968165543 0.782722728 0.939755342 0.7551908 0.961256404 0.868935035 0.756254796 0.886203015 0.808123362 1 10.49595193 -7.387241673 6.020177701 0.986072809 0.851463014 0.014473092 0.087387965 0.140930247 6.351759187 0.010621949 0.012088448 4.10E-08 7.387241673 -0.134609795 EATGLS(ph)PQAAQEK ddPTM_HeLa_Curcumin_4h_R1 2 EATGLSPQAAQEK 13 0 C9JRM9;P17029 C9JRM9 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 0 EAT(0.007)GLS(0.993)PQAAQEK;EAT(0.077)GLS(0.923)PQAAQEK ; 184.48 7.74E-05 34042900 10850.7 7121 9580 11328.1 11242.5 12153.4 9041.5 5441 10875.8 8123.8 TRUE FALSE FALSE 9991.855645 7736.507509 9935.043227 11281.22732 11108.44053 9632.647843 9295.180156 7099.935853 9682.75195 8406.101445 1.188643239 0.920344295 1.181884765 1.342028454 1.321473528 1.145911444 1.105765879 0.844616961 1.151871889 1 13.03722115 -9.49490546 0.886509868 0.986444228 1.14448437 0 0.154024958 1.416094135 1.692864311 0.163537353 0.028181092 3.20E-10 9.49490546 0.158040142 EATGLS(ph)PQAAQEKDGIVIVK ddPTM_HeLa_Curcumin_4h_R1 1 EATGLSPQAAQEKDGIVIVK 20 1 C9JRM9;P17029 C9JRM9 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 1 0 EAT(0.273)GLS(0.727)PQAAQEKDGIVIVK 96.128 0.00034213 15269000 2834.1 1814.5 1893.9 2482.2 2453 2905.3 2099.3 1246.6 2659.3 2135.9 TRUE FALSE FALSE 2609.777994 1971.337295 1964.0896 2471.929314 2423.749577 2302.708031 2158.200708 1626.682601 2367.581443 2210.122366 1.180829638 0.891958439 0.88867912 1.118458123 1.096658545 1.041891646 0.976507338 0.736014723 1.071244506 1 11.10991053 -4.222711252 1.945265436 1.060469083 0.616258058 0.484520055 0.090021499 0.613745897 2.227240985 0.015115033 0.503678095 5.99E-05 4.222711252 -0.444211026 EATNPPVIQEEK(ac)PK ddPTM_HeLa_Curcumin_4h_R1 2 EATNPPVIQEEKPK 14 1 P30101 P30101 PDIA3 Protein disulfide-isomerase A3 0 1 ; EATNPPVIQEEK(1)PK;EATNPPVIQEEK(1)PK 264.28 7.83E-77 8352800 1494.56 2316.1 1652.08 1397.71 3378.2 4109.7 3061.5 1893.3 4305.4 1506.17 FALSE TRUE FALSE 1376.263999 2516.293364 1713.307538 1391.926646 3337.917171 3257.301894 3147.39745 2470.558454 3833.108392 1558.509295 0.883064351 1.614551399 1.099324555 0.893114113 2.141737095 2.090011207 2.019492254 1.585206108 2.459470985 1 10.60595104 -5.763356122 24.99999936 1.008958388 1.972774616 0.119126001 0.519897144 17.59400719 229482.7522 0.037450347 0.070460246 1.72E-06 5.763356122 0.963816227 EATNPPVIQEEKPK ddPTM_HeLa_Curcumin_4h_R1 2 EATNPPVIQEEKPK 14 1 P30101 P30101 PDIA3 Protein disulfide-isomerase A3 0 0 ; ; 154.13 0.00042525 17321200 5444.9 4533 5207.4 4721.8 4978.8 5392.1 4021.1 3163.4 5644.1 5151.4 FALSE FALSE TRUE 5013.93042 4924.812321 5400.390825 4702.262443 4919.431062 4273.717679 4133.921244 4127.906097 5024.956351 5330.410767 0.9406274 0.923908595 1.013128455 0.882157614 0.922899055 0.801761415 0.775535212 0.774406754 0.942695895 1 12.380031 -5.337341938 0.932475624 0.970657539 0.750757938 0.826660364 0.034470785 0.200274219 0.289362986 0.00580588 0.03041924 4.60E-06 5.337341938 -0.219899601 EATNTTSEPSAPSQDLLDLSPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 EATNTTSEPSAPSQDLLDLSPSPR 24 0 I3NI44;J3KQU4;I3L4I4;O75674-2;O75674-3;O75674 I3NI44 TOM1L1 TOM1-like protein 1 1 0 EATNTTSEPSAPSQDLLDLS(0.142)PS(0.858)PR;EATNTTSEPSAPSQDLLDLS(0.025)PS(0.975)PR;EATNTTSEPSAPS(0.002)QDLLDLS(0.386)PS(0.612)PR ;; 211.09 1.32E-19 105533500 9670.8 8139.4 8371 8729.1 8519.1 8054.7 5499.08 3699.28 9699.5 7619.09 TRUE FALSE FALSE 8905.345975 8842.933468 8681.236624 8692.981297 8417.515297 6384.064425 5653.369385 4827.173443 8635.489117 7883.85281 1.129567762 1.121651264 1.101141388 1.1026311 1.067690569 0.809764538 0.717082056 0.612286094 1.095338704 1 12.94468513 -5.046399164 1.984698311 1.075401974 0.647709688 0.945828317 0.042067427 0.076056257 0.571366912 0.008573918 0.033457431 8.99E-06 5.046399164 -0.427692286 EATPDGGEDS(ph)DS ddPTM_HeLa_Curcumin_4h_R1 2 EATPDGGEDSDS 12 0 D6RJC6;A0A087WYP9;A6NFV8;Q96EV8-3;Q96EV8 D6RJC6 DTNBP1 Dysbindin 1 0 EATPDGGEDS(0.993)DS(0.007);EATPDGGEDS(1)DS ; 205.53 5.30E-09 13931900 9978.8 8830.8 9273.3 8751 9674.8 10617.1 9319.9 8975.5 8765 9210.2 TRUE FALSE FALSE 9188.96745 9594.095003 9616.976656 8714.790681 9559.434329 8414.993781 9581.391311 11712.08863 7803.501429 9530.253764 0.964189168 1.006698797 1.009099746 0.914434274 1.003061887 0.882976885 1.005365812 1.228937751 0.818813604 1 13.21829891 -4.273729407 4.432436974 0.97652477 1.243948939 0.609513013 0.064012469 0.06083358 2.908583363 0.005291467 0.049707641 5.32E-05 4.273729407 0.267424169 LNCS(ph)TSPEIFRK ddPTM_HeLa_Curcumin_4h_R1 1 LNCSTSPEIFRK 12 1 Q9BRS8 Q9BRS8 LARP6 La-related protein 6 1 0 LNCS(0.673)T(0.278)S(0.048)PEIFRK 130.15 0.0038618 20724000 3386.2 2675.6 2483.8 2664 2311.5 2509.1 1127.3 258.26 2989.7 2615.5 TRUE FALSE FALSE 3118.178697 2906.866942 2575.851813 2652.977074 2283.936872 1988.684377 1158.929004 337.0022851 2661.73739 2706.38843 1.152154902 1.07407603 0.951767228 0.980264712 0.843905792 0.734811143 0.42821976 0.124521034 0.983501614 1 11.4021532 -4.741019574 0.874372356 1.066005073 1.93E-13 0.95868185 0.061705915 0.188964758 0.164139094 0.011584546 0.163766835 1.82E-05 4.741019574 -1.066005073 down NSTDLDSAPEDPTS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 NSTDLDSAPEDPTSPK 16 0 I3L2J0;A0A0A0MQR4;Q96RK0;I3L373;I3L135;I3L1Q4 I3L2J0 CIC Protein capicua homolog 1 0 NSTDLDSAPEDPT(0.5)S(0.5)PK 168.69 0.0001514 25644000 5272.4 5073.8 4955.6 5154.5 5506.3 4271.4 2084.1 732.58 4870.8 3155.3 TRUE FALSE FALSE 4855.083977 5512.356664 5139.258895 5133.172045 5440.640969 3385.463491 2142.574237 955.9402696 4336.485426 3264.94644 1.487033269 1.688345204 1.574071425 1.572207122 1.666379853 1.036912413 0.656235646 0.292788959 1.328194966 1 11.67284361 -4.738845012 2.275330972 1.347880279 0.346524159 0.755028736 0.221869284 0.17077276 1.664955378 0.042717224 0.230413402 1.82E-05 4.738845012 -1.001356121 down EATSDPS(ph)RTPEEEPLNLEGLVAHR ddPTM_HeLa_Curcumin_4h_R1 3 EATSDPSRTPEEEPLNLEGLVAHR 24 1 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0 A0A087WWW7 TNS1 Tensin-1 1 0 EAT(0.024)S(0.019)DPS(0.478)RT(0.478)PEEEPLNLEGLVAHR;EAT(0.021)S(0.096)DPS(0.463)RT(0.42)PEEEPLNLEGLVAHR;EAT(0.055)S(0.055)DPS(0.445)RT(0.445)PEEEPLNLEGLVAHR ;; 115.39 2.68E-07 31687400 5755.6 5628.5 5771.2 6338.1 5683 6152.6 4758.4 10097 6676.8 5700.1 TRUE FALSE FALSE 5300.038187 6115.00246 5985.085749 6311.874622 5615.233937 4876.481406 4891.907897 13175.52882 5944.371745 5898.178051 0.898589046 1.036761252 1.014734668 1.070139722 0.952028557 0.826777585 0.829393052 2.233830296 1.007831858 1 12.52605366 -4.258033436 24.99886304 0.954409145 2.233830774 0.95816878 0.079867129 47.23716816 346694.3478 0.01169515 0.113681443 5.52E-05 4.258033436 1.279421629 EATSLAGSQSY(ph)EDMR ddPTM_HeLa_Curcumin_4h_R1 1 EATSLAGSQSYEDMR 15 0 P15391-2 P15391-2 1 0 EATSLAGS(0.001)QS(0.001)Y(0.998)EDMR 110.38 0.013569 19828000 3121.6 2973.1 3276.5 3124.3 3907.8 3943.5 3224.9 2639.7 3288.3 2618.7 TRUE FALSE FALSE 2874.522066 3230.081516 3397.929972 3111.372474 3861.202037 3125.573648 3315.382015 3444.532378 2927.581717 2709.69963 1.060826829 1.192044122 1.253987687 1.148235192 1.424955738 1.153476058 1.22352381 1.271186053 1.080408206 1 11.40391722 -7.248901626 1.456885369 1.020438421 1.248372255 0.580344884 0.075005303 0.159100756 0.644277467 0.013274309 0.015834411 5.64E-08 7.248901626 0.227933834 EATTDFTVDSRPLTQVGGDHIK ddPTM_HeLa_Curcumin_4h_R1 1 EATTDFTVDSRPLTQVGGDHIK 22 1 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 134.4 1.03E-05 11794000 1774.8 1478.4 1388.9 1470.4 1504.9 2042.2 1415.2 1285 1879.8 1584 FALSE FALSE TRUE 1634.322707 1606.186308 1440.373856 1464.315874 1486.95505 1618.6247 1454.906703 1676.790585 1673.590643 1639.043882 0.997119556 0.979953207 0.878789074 0.893396382 0.90720881 0.987542016 0.887655736 1.023029708 1.021077386 1 10.67863876 -6.947651309 8.681920124 0.998121034 0.927671353 0.390388043 0.043353071 0.215585787 32.89564095 0.006452298 0.008482143 1.13E-07 6.947651309 -0.070449681 EATTEFSVDAR ddPTM_HeLa_Curcumin_4h_R1 2 EATTEFSVDAR 11 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 235.66 2.61E-16 53512900 6252.6 4795.4 4935.1 4948.4 4960.6 6152.1 4652.8 4421.6 5649.4 5058.9 FALSE FALSE TRUE 5757.700112 5209.893008 5117.999147 4927.924832 4901.448085 4876.085112 4783.345046 5769.725485 5029.674954 5234.696398 1.099910993 0.995261733 0.977706969 0.941396493 0.936338559 0.931493393 0.913776976 1.102208236 0.960834129 1 12.35389015 -6.978778712 3.656530141 1.047325938 0.960975064 0.077510125 0.060825998 0.208468644 6.032406425 0.009788781 0.01274288 1.05E-07 6.978778712 -0.086350874 EATWTMSNITAGR ddPTM_HeLa_Curcumin_4h_R1 2 EATWTMSNITAGR 13 0 P52292 P52292 KPNA2 Importin subunit alpha-1 0 0 ; ; 160.72 6.12E-05 2798100 1102.46 1222 1219.55 887.96 1230.09 1402.25 1458.21 1179.4 2219.99 866.86 FALSE FALSE TRUE 1015.199128 1327.624235 1264.747596 884.2858568 1215.42198 1111.407543 1499.123448 1538.993631 1976.462651 896.9833205 1.131792648 1.480099133 1.410001242 0.985844259 1.355010681 1.239050402 1.671294676 1.715743867 2.2034553 1 9.808937348 -1 0.209165045 0.999366563 4.519253819 0 0.405037688 25.70968338 0.301098172 0.144635792 30.32600122 0.1 1 3.519887256 EAVAMESYAK ddPTM_HeLa_Curcumin_4h_R1 2 EAVAMESYAK 10 0 F5GWF6;P78371;P78371-2 F5GWF6 CCT2 T-complex protein 1 subunit beta 0 0 ; ; 178.22 1.23E-15 7843800 6185.7 5328.4 5192.7 6238.9 5808 7446.5 5489.7 5728.8 5677.4 5146.3 FALSE FALSE TRUE 5696.095318 5788.963153 5385.14603 6213.085085 5738.743393 5902.011961 5643.726207 7475.484748 5054.603424 5325.133542 1.069662436 1.087101968 1.011269668 1.166747282 1.077671264 1.108331259 1.059828108 1.403811696 0.949197496 1 12.37860199 -1.886180072 1.300829625 1.049890345 200 0.745456186 0.059738439 281.9140705 1.084377556 0.008067346 166695.8918 0.012996306 1.886180072 198.9501096 EAVAPVQEES(ph)DLEK ddPTM_HeLa_Curcumin_4h_R1 2 EAVAPVQEESDLEK 14 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5;E7ET01;E7ERR6;E7EUM4;E7ERH4;E7EU01 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 0 EAVAPVQEES(1)DLEK;EAVAPVQEES(1)DLEK ; 152.94 0.00044372 12940800 4875.6 4076.7 4284.1 3993.6 4786.8 5882.5 4456.5 3381.9 4885.6 4419.3 TRUE FALSE FALSE 4489.691115 4429.071783 4442.872515 3977.075541 4729.720536 4662.403191 4581.537396 4413.025742 4349.661903 4572.870346 0.98181028 0.968553982 0.97157194 0.869710978 1.034300161 1.019579135 1.001895319 0.965045017 0.951188548 1 12.1588843 -2.808663682 12.65501212 0.984846346 0.981470865 0 0.044050322 0 0 0.005526965 0 0.00155359 2.808663682 -0.003375481 EAVLLLK ddPTM_HeLa_Curcumin_4h_R1 2 EAVLLLK 7 0 P36578;H3BM89;H3BTP7 P36578 RPL4 60S ribosomal protein L4 0 0 ; ; 126.54 0.0088642 7451600 9374.5 7621.8 8945.3 8482.7 9480.1 11054 9283.5 8443.6 8467.1 7526.6 FALSE FALSE TRUE 8632.498433 8280.59443 9276.820687 8447.600835 9367.055999 8761.275796 9543.970025 11018.01477 7538.280314 7788.14879 1.108414678 1.063230127 1.191145796 1.084673786 1.202732029 1.124949719 1.225447829 1.414715495 0.967916833 1 12.92706473 -1 0.255237248 1.028925712 3.137743743 0.772325491 0.058182161 16.68226735 0.209226699 0.029063177 15.39470832 0.1 1 2.10881803 EAVVDLHADDS(ph)RISEDETER ddPTM_HeLa_Curcumin_4h_R1 1 EAVVDLHADDSRISEDETER 20 1 Q9UKV3-5;G3V3T3 Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 EAVVDLHADDS(0.497)RIS(0.24)EDET(0.263)ER 95.954 0.00034656 79224000 1444.3 1258.6 1408.8 1247.3 1599.3 1401.6 1181.1 1102.4 1141.2 1185.2 TRUE FALSE FALSE 1329.982131 1367.387776 1461.011367 1242.139003 1580.229392 1110.892361 1214.238487 1438.516685 1016.013215 1226.385612 1.084473039 1.114973759 1.191314831 1.012845382 1.288525711 0.905826316 0.990095183 1.172972572 0.828461461 1 10.26019696 -8.853669654 0.882398922 1.003922533 1.091935826 0.201020997 0.117884101 1.006054908 1.521452301 0.050927523 0.019976744 1.40E-09 8.853669654 0.088013293 EAVVDLHADDS(ph)RISEDETERNGDDGTHDK ddPTM_HeLa_Curcumin_4h_R1 1 EAVVDLHADDSRISEDETERNGDDGTHDK 29 2 Q9UKV3-5;G3V3T3 Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 EAVVDLHADDS(0.628)RIS(0.168)EDET(0.198)ERNGDDGT(0.007)HDK 52.824 0.0020377 142690000 1622.4 1630.4 1643.3 1614.9 1699.8 2498.8 1634.8 1560.5 2224.8 1398 TRUE FALSE FALSE 1493.985328 1771.324511 1704.202144 1608.217972 1679.530995 1980.520713 1680.668088 2036.289266 1980.745006 1446.580396 1.03277034 1.224490886 1.178090169 1.111737707 1.161035363 1.36910518 1.161821419 1.40765717 1.36926023 1 10.49843079 -4.742762137 0.22909971 0.962537894 1.583557536 0 0.14254381 3.807910813 0.20607669 0.073558702 0.673881869 1.81E-05 4.742762137 0.621019641 EAVVDLHADDSRIS(ph)EDETER ddPTM_HeLa_Curcumin_4h_R1 2 EAVVDLHADDSRISEDETER 20 1 Q9UKV3-5;G3V3T3 Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 EAVVDLHADDS(0.242)RIS(0.744)EDET(0.014)ER;EAVVDLHADDS(0.082)RIS(0.667)EDET(0.251)ER ; 116.61 5.99E-05 44752000 3601.2 2964.1 3183.6 3114.2 3639.8 3956.6 3506 3213.3 2987.3 2935.5 TRUE FALSE FALSE 3316.16122 3220.303596 3301.587017 3101.314266 3596.397762 3135.95656 3604.368924 4193.020378 2659.600664 3037.508407 1.091737298 1.06017932 1.086939219 1.021005986 1.183995986 1.032410825 1.18662023 1.380414411 0.875586273 1 11.56867269 -1.000000031 0.720575719 1.049230407 49.35814038 0.666596192 0.074288212 100.9295114 0.460850281 0.00867073 7891.552094 0.099999993 1.000000031 48.30890998 EAVVDLHADDSRISEDET(ph)ER ddPTM_HeLa_Curcumin_4h_R1 1 EAVVDLHADDSRISEDETER 20 1 Q9UKV3-5;G3V3T3 Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 EAVVDLHADDS(0.152)RIS(0.32)EDET(0.528)ER 98.76 0.00051599 70190000 2432.7 2329.1 2534.5 2345.3 2826.7 2872.9 2402.5 2489.9 2126.7 2558.2 TRUE FALSE FALSE 2240.149228 2530.417026 2628.4308 2335.59577 2792.993449 2277.028156 2469.907684 3249.059048 1893.406331 2647.09726 0.846266309 0.955921441 0.992948329 0.882323368 1.055115538 0.860198146 0.933062688 1.227404485 0.71527645 1 11.37019549 -4.261364072 22.41865982 0.93363347 1.227404836 0.494266024 0.09301399 0.742997648 219128.2307 0.009716506 0.074916378 5.48E-05 4.261364072 0.293771365 EAVVDLHADDSRISEDET(ph)ERNGDDGTHDK ddPTM_HeLa_Curcumin_4h_R1 1 EAVVDLHADDSRISEDETERNGDDGTHDK 29 2 Q9UKV3-5;G3V3T3 Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 EAVVDLHADDS(0.048)RIS(0.089)EDET(0.814)ERNGDDGT(0.049)HDK 43.956 0.0091932 4629700 1129.1 874.99 705.31 706.06 1050.9 901.51 723.68 744.06 1234.5 1091.9 TRUE FALSE FALSE 1039.730544 950.6202367 731.4494091 703.1385108 1038.368704 714.5266639 743.9845131 970.9204688 1099.078439 1129.843444 0.920243021 0.841373415 0.647390055 0.622332691 0.919037686 0.632412099 0.658484604 0.859340711 0.972770559 1 10.14190716 -7.145286804 2.186231676 0.966094357 0.721126422 0.563184471 0.094892204 0.15897885 1.460787304 0.016475544 0.020393305 7.16E-08 7.145286804 -0.244967936 EAYPEEAYIADLDAK ddPTM_HeLa_Curcumin_4h_R1 1 EAYPEEAYIADLDAK 15 0 P53396;P53396-2 P53396 ACLY ATP-citrate synthase 0 0 248.19 7.00E-29 9631500 2080.7 1645.6 1720 1981.9 2036 1988.3 1629.9 1677 1907.2 1964.1 FALSE FALSE TRUE 1916.010399 1787.838331 1783.744713 1973.699423 2011.72203 1575.904167 1675.630607 2188.30958 1697.984932 2032.352329 0.942755039 0.879689169 0.877674942 0.971140385 0.989849054 0.775408941 0.824478405 1.07673731 0.835477642 1 10.98893481 -8.226597328 0.752776951 0.994416521 0.90842706 0 0.09542973 0.822891448 1.008677169 0.0316773 0.019161363 5.93E-09 8.226597328 -0.085989462 EAYPGDVFYLHSR ddPTM_HeLa_Curcumin_4h_R1 2 EAYPGDVFYLHSR 13 0 P25705;P25705-2;P25705-3 P25705 ATP5A1 "ATP synthase subunit alpha, mitochondrial" 0 0 ; ; 147.7 0.00039933 34437800 6304.8 4968.4 5466.9 5020.5 5914.7 12496.1 8086.1 6842.4 6928.1 5098.3 FALSE FALSE TRUE 5805.768427 5397.846357 5669.508123 4999.726501 5844.171066 9904.268 8312.974203 8928.616261 6168.104763 5275.465546 1.10052248 1.023198107 1.074693423 0.947731808 1.107801959 1.877420659 1.57578021 1.692479305 1.169205772 1 12.3650827 -5.31917816 6.562632136 1.043216954 1.700390565 0.916731847 0.090344984 0.036922329 3.419191927 0.011127392 0.02521469 4.80E-06 5.31917816 0.657173611 EAYSGCSGPVDSECPPPPSS(ph)PVHK ddPTM_HeLa_Curcumin_4h_R1 2 EAYSGCSGPVDSECPPPPSSPVHK 24 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 0 EAYSGCSGPVDSECPPPPS(0.248)S(0.752)PVHK;EAYSGCSGPVDSECPPPPS(0.178)S(0.822)PVHK ; 174.61 1.25E-10 26523000 3813.1 3704.4 3546.8 3797.5 4372.4 4995.1 3817.5 3180.4 3813.4 2974.4 TRUE FALSE FALSE 3511.289111 4024.59183 3678.247528 3781.786951 4320.261986 3959.059954 3924.608776 4150.089319 3395.079561 3077.760179 1.140858581 1.307636592 1.195105309 1.228746469 1.403703257 1.286344525 1.275150937 1.348412182 1.10310075 1 11.5876651 -7.651554479 0.447205552 0.994921265 1.33092748 0.716856308 0.061502598 0.25638586 0.133141241 0.031102308 0.025529159 2.23E-08 7.651554479 0.336006215 ECCVTAGGR ddPTM_HeLa_Curcumin_4h_R1 1 ECCVTAGGR 9 0 O43818 O43818 RRP9 U3 small nucleolar RNA-interacting protein 2 0 0 93.162 0.017128 373680 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 ECINAAPDS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 ECINAAPDSPSK 12 0 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 0 ECINAAPDS(0.85)PS(0.15)K;ECINAAPDS(0.776)PS(0.224)K ; 141 0.0011456 150173000 9935.8 9115.3 10469.8 8976.9 11463.9 12604.5 10936 8693.8 8766.1 7414 TRUE FALSE FALSE 9149.370946 9903.185915 10857.82 8939.755966 11327.20048 9990.184618 11242.83473 11344.4996 7804.480762 7671.635948 1.192623191 1.290883194 1.415320027 1.165299817 1.476503911 1.3022235 1.46550681 1.478758856 1.01731636 1 12.90531854 -7.430397791 0.1523983 0.7710786 1.670964594 0.771690233 0.082711757 1.342466311 0.185884746 0.49764497 0.481876942 3.71E-08 7.430397791 0.899885994 ECINAAPDSPS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 ECINAAPDSPSK 12 0 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 0 ECINAAPDS(0.084)PS(0.916)K 196.8 2.16E-06 61854000 5339 4436 5427.7 4533.3 5325 6116.7 5229.1 4621.1 4708.4 3886.1 TRUE FALSE FALSE 4916.412516 4819.428074 5628.855337 4514.542406 5261.502853 4848.027471 5375.814473 6030.052117 4191.9003 4021.141686 1.222640956 1.198522323 1.399815221 1.12270165 1.308459951 1.205634581 1.336887604 1.49958708 1.042465207 1 11.97338946 -13.37766654 0.078107357 3.42E-13 1.614927903 0.632887739 0.089906232 81.48715562 0.503761857 14.41548681 1.765109225 4.19E-14 13.37766654 1.614927903 ECPDQLGPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 ECPDQLGPSPK 11 0 E7EWM1;Q15596 E7EWM1 NCOA2 Nuclear receptor coactivator 2 1 0 ECPDQLGPS(1)PK 133.98 0.0022497 28836000 4635.9 3961 4109.9 3933.1 4164.3 3933.8 3247.5 1437.8 4114 3586.3 TRUE FALSE FALSE 4268.963623 4303.37119 4262.216509 3916.825874 4114.643442 3117.885537 3338.61611 1876.178601 3662.704493 3710.923658 1.150377646 1.159649615 1.14855947 1.055485436 1.108792263 0.840191237 0.899672539 0.505582646 0.987006155 1 11.85756261 -4.01014633 0.899326485 1.086790777 1.63E-14 0.831643026 0.07819824 0.958924444 0.428522294 0.012925121 1.134075595 9.77E-05 4.01014633 -1.086790777 ECPSDECGAGVFMASHFDR ddPTM_HeLa_Curcumin_4h_R1 1 ECPSDECGAGVFMASHFDR 19 0 P62979;A0A2R8Y422 P62979 RPS27A Ubiquitin-40S ribosomal protein S27a;Ubiquitin;40S ribosomal protein S27a 0 0 114.52 0.0012527 90244000 1845.9 1179.7 1137.1 1633.5 1434.9 1456.8 1220.1 968.46 1839.5 1055.7 FALSE FALSE TRUE 1699.795067 1281.668011 1179.241926 1626.74101 1417.789755 1154.643258 1254.332722 1263.738996 1637.711452 1092.385496 1.556039578 1.173274467 1.079510786 1.489163867 1.297884089 1.056992483 1.148250985 1.156861749 1.499206514 1 10.09326635 -5.27055891 23.95746835 1.26673387 1.123456664 0.161431492 0.175860463 754.5705091 1982298.605 0.031863538 0.072257077 5.36E-06 5.27055891 -0.143277206 ECS(ph)PTSSLER ddPTM_HeLa_Curcumin_4h_R1 1 ECSPTSSLER 10 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 0 ECS(0.927)PT(0.064)S(0.009)SLER 102.05 0.011218 43001000 2320.1 1942.6 2040 2187.2 2240.3 2166.4 1350.7 1009 2198.5 1790.2 TRUE FALSE FALSE 2136.461637 2110.509688 2115.604195 2178.149946 2213.585886 1717.06422 1388.597007 1316.639455 1957.33005 1852.409317 1.153342092 1.139332257 1.142082463 1.175847004 1.194976653 0.926935642 0.749616726 0.710771342 1.056640146 1 10.8551872 -4.932714901 2.972905241 1.099224505 0.724962608 0.873963798 0.059481517 0.085624196 1.513615701 0.011353524 0.040392694 1.17E-05 4.932714901 -0.374261896 ECS(ph)VEKGTGDSLR ddPTM_HeLa_Curcumin_4h_R1 1 ECSVEKGTGDSLR 13 1 Q5T757;Q05519-2;Q05519 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 0 ECS(0.995)VEKGT(0.004)GDS(0.001)LR 74.237 0.01295 179190000 4363.5 3100.9 3867.1 4228.7 3499.4 4505.7 3615.7 2584.9 4592.4 3920.8 TRUE FALSE FALSE 4018.124371 3368.927979 4010.418128 4211.20276 3457.671941 3571.16703 3717.146811 3373.024111 4088.62521 4057.047508 0.990406043 0.830389088 0.988506573 1.037996906 0.852263113 0.880237913 0.91621969 0.831398721 1.007783419 1 11.98621448 -1 0.179629459 1.017181384 0.27978373 0.374297391 0.060197812 42.37272014 0.459521621 0.077104872 8.575504307 0.1 1 -0.737397654 ECSEAMEVETSVISIDS(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 1 ECSEAMEVETSVISIDSPQK 20 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 ECSEAMEVETSVIS(0.001)IDS(0.999)PQK 218.81 3.97E-19 18188000 4771.8 4264.2 4918.3 4801.2 5625.6 5139.7 4929.6 2785.8 4596 3984.8 TRUE FALSE FALSE 4394.106995 4632.778447 5100.576525 4781.333907 5558.518394 4073.668284 5067.911309 3635.177596 4091.830299 4123.271503 1.065684613 1.123568614 1.237021748 1.159597155 1.348084498 0.987969936 1.229099589 0.881624601 0.992374695 1 12.00957375 -7.51336403 1.633182608 1.022602769 1.149045347 0.164391612 0.124007384 0.432347579 2.295446388 0.023064046 0.02476775 3.07E-08 7.51336403 0.126442578 EDAANNYAR ddPTM_HeLa_Curcumin_4h_R1 2 EDAANNYAR 9 0 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;A0A1W2PQM2;P0DPH7-2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;F8VWV9;Q9NY65-2;Q9NY65;C9J2C0;F8VX09;C9K0S6;A6NHL2-2;A6NHL2;P68363;P68363-2;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2 Q9BQE3;P68363;P68366-2 TUBA1C;TUBA1B;TUBA1A;TUBA8;TUBAL3;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-8 chain;Tubulin alpha chain-like 3;Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 0 ; ; 167.23 1.22E-11 58893000 7461.9 6631.9 7684.3 6867.1 8169 8533.3 6121 5823.4 6707.1 6088.9 FALSE FALSE TRUE 6871.282741 7205.131885 7969.086918 6838.68576 8071.59001 6763.39739 6292.738786 7598.927852 5971.34791 6300.488822 1.09059518 1.143582996 1.264836292 1.085421457 1.281105362 1.07347185 0.998769931 1.206085443 0.947759464 1 12.62124805 -8.083977649 0.94957337 1.016363131 1.146387209 0.371629168 0.085638446 0.430430225 0.825087503 0.024507826 0.018202258 8.24E-09 8.083977649 0.130024078 EDCEQWWEDCR ddPTM_HeLa_Curcumin_4h_R1 1 EDCEQWWEDCR 11 0 P15328 P15328 FOLR1 Folate receptor alpha 0 0 189.17 0.00038081 6207800 497.43 424.68 517.11 808.47 580.19 1394.4 698.48 1001.3 657.27 489.85 FALSE FALSE TRUE 458.0578906 461.3874469 536.2745515 805.1247654 573.2716132 1105.185722 718.0774689 1306.591761 585.1691254 506.872251 0.903694944 0.910263771 1.058007319 1.588417523 1.130998219 2.180402892 1.416683331 2.577753582 1.154470627 1 8.985478375 -3.935517305 0.431478386 0.926496469 3.811146234 0.689972128 0.301241871 2.256471659 0.231862114 0.063768965 3.535317422 0.000116007 3.935517305 2.884649765 EDDDVIVNKPHVS(ph)DEEEEEPPFYHHPFK ddPTM_HeLa_Curcumin_4h_R1 1 EDDDVIVNKPHVSDEEEEEPPFYHHPFK 28 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-2;H7C1M2;H7C2G8;J3QSZ5 P18583-10 SON Protein SON 1 0 EDDDVIVNKPHVS(0.932)DEEEEEPPFY(0.068)HHPFK 67.827 0.00013043 44657000 4603.2 3811.9 4205.9 3810.9 5307.6 5689.4 4480.2 2747.4 3897.9 4016.4 TRUE FALSE FALSE 4238.851863 4141.383651 4361.774354 3795.131506 5244.310337 4509.354307 4605.902354 3585.069613 3470.310122 4155.969601 1.019942942 0.996490362 1.049520274 0.913175954 1.261874085 1.085030628 1.108261801 0.862631337 0.835018168 1 12.02096939 EDEEEDDDVVAPKPPIEPEEEK ddPTM_HeLa_Curcumin_4h_R1 2 EDEEEDDDVVAPKPPIEPEEEK 22 1 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 0 0 ; ; 135.43 8.22E-06 9082500 3052 2703.8 3841.1 2807.2 3527 3539.4 3339.6 2895.6 2632.84 2332.81 FALSE FALSE TRUE 2810.43098 2937.504424 3983.454545 2795.58455 3484.942829 2805.288543 3433.300188 3778.45511 2344.024039 2413.874974 1.164281916 1.216924843 1.650232339 1.158131461 1.443713061 1.16215155 1.422318979 1.565306883 0.971062737 1 11.23713524 -7.51758563 0.967783431 1.042028609 1.3833286 0.506310622 0.154781309 0.294730716 0.564084149 0.035205174 0.036555401 3.04E-08 7.51758563 0.341299991 EDEEESLNEVGYDDIGGCR ddPTM_HeLa_Curcumin_4h_R1 1 EDEEESLNEVGYDDIGGCR 19 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 212.7 1.51E-48 0 592.86 550.89 530.08 377.19 620.03 630.8 538.76 511.85 516.58 380.92 FALSE FALSE TRUE 545.9345054 598.5064769 549.7252311 375.6292877 612.6365472 499.9649694 553.8761556 667.9107087 459.9124664 394.1569416 1.385068859 1.51844713 1.394686159 0.952994221 1.554295973 1.268441366 1.405217306 1.694529864 1.166825743 1 8.622626372 -11.90849325 0.24871617 5.41E-10 1.437447185 0.277569114 0.192485699 16.49112237 0.439627437 8.349568933 0.120493137 1.23E-12 11.90849325 1.437447185 EDEGEPGDEGQLEDEGS(ph)QEKQGR ddPTM_HeLa_Curcumin_4h_R1 2 EDEGEPGDEGQLEDEGSQEKQGR 23 1 Q969E4 Q969E4 TCEAL3 Transcription elongation factor A protein-like 3 1 0 EDEGEPGDEGQLEDEGS(1)QEKQGR;EDEGEPGDEGQLEDEGS(1)QEKQGR ; 101.43 2.03E-05 26451000 2567.3 1843.07 1832.85 2164.6 2205.6 2568.5 1927.63 2446 2135.5 1867.32 TRUE FALSE FALSE 2364.095496 2002.376758 1900.777033 2155.643459 2179.299661 2035.764147 1981.71411 3191.77414 1901.240993 1932.209231 1.223519409 1.036314663 0.983732508 1.115636663 1.127879748 1.053594049 1.025620869 1.651878114 0.983972627 1 10.91603561 -4.257469816 24.9537214 1.089480705 1.651878338 0.839557923 0.076576108 136.1541361 855865.4291 0.012685419 0.128621939 5.53E-05 4.257469816 0.562397633 EDEGPPGY(ph)PEPLAPGHGSPFPSLSK ddPTM_HeLa_Curcumin_4h_R1 1 EDEGPPGYPEPLAPGHGSPFPSLSK 25 0 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 0 EDEGPPGY(0.627)PEPLAPGHGS(0.212)PFPS(0.128)LS(0.033)K 65.753 0.006022 22056000 2763 2431.3 2931.2 2122.8 2990 3191 2590.3 1817.2 2534.1 1850.3 TRUE FALSE FALSE 2544.305634 2641.450738 3039.832851 2114.016416 2954.346203 2529.15063 2662.976847 2371.255915 2256.11557 1914.597787 1.328898242 1.379637413 1.58771355 1.104156931 1.543063625 1.320982739 1.390880562 1.23851387 1.178375732 1 10.90282563 -8.890154674 0.69299555 0.991959126 1.370271606 0.351455683 0.140445494 0.425373524 0.373442817 0.087696659 0.026886812 1.29E-09 8.890154674 0.37831248 EDEGPPGYPEPLAPGHGS(ph)PFPSLSK ddPTM_HeLa_Curcumin_4h_R1 1 EDEGPPGYPEPLAPGHGSPFPSLSK 25 0 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 0 EDEGPPGYPEPLAPGHGS(0.883)PFPS(0.091)LS(0.026)K 93.553 7.11E-06 10200000 1957.4 2160.9 2197.7 1763.5 2513.1 2490.8 1927.4 1342.6 2140.3 1333.5 TRUE FALSE FALSE 1802.469725 2347.678567 2279.148695 1756.203104 2483.132924 1974.180003 1981.477657 1751.952559 1905.514445 1379.839026 1.306289858 1.70141482 1.651749699 1.27275941 1.799581602 1.430732112 1.436020883 1.269678946 1.380968656 1 10.43028425 -8.09023056 0.992894984 1.056447822 1.505743722 0.215491508 0.200464382 0.251793075 0.524944131 0.05010241 0.037647391 8.12E-09 8.09023056 0.449295901 EDEIS(ph)PPPPNPVVK ddPTM_HeLa_Curcumin_4h_R1 4 EDEISPPPPNPVVK 14 0 K7EMU2;K7EMZ6;K7EIE5;K7EID3;K7EJ40;K7EK41;K7EPB2;P10644-2;P10644 K7EMU2 PRKAR1A "cAMP-dependent protein kinase type I-alpha regulatory subunit;cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed" 1 0 EDEIS(1)PPPPNPVVK;EDEIS(1)PPPPNPVVK;EDEIS(1)PPPPNPVVK;EDEIS(1)PPPPNPVVK ;;; 168.07 0.00020876 227276000 22102.7 18981.5 20245.2 19411.2 24175.5 24298.7 18952.5 17760.3 19353 17549 TRUE FALSE FALSE 20353.24797 20622.17628 20995.50492 19330.8816 23887.22295 19258.87572 19484.25614 23175.33371 17230.02432 18158.82644 1.120845999 1.135655784 1.156214857 1.064544653 1.315460722 1.060579315 1.072990934 1.27625724 0.948851203 1 14.14838335 -9.200449168 0.339596348 0.942228078 1.165137516 0.430808241 0.081414076 2.534731944 0.399546971 0.217185635 0.036313671 6.30E-10 9.200449168 0.222909438 EDEKGDDVDDPENQNS(ph)ALADTDASGGLTK ddPTM_HeLa_Curcumin_4h_R1 1 EDEKGDDVDDPENQNSALADTDASGGLTK 29 1 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 EDEKGDDVDDPENQNS(0.982)ALADT(0.014)DAS(0.004)GGLTK 67.69 0.00011918 4875200 1380.6 1071.6 1089.9 1294.9 1018.2 2118.1 1380 1046.1 1165.2 1143 TRUE FALSE FALSE 1271.324053 1164.224329 1130.292653 1289.542047 1006.05863 1678.782184 1418.719086 1365.051074 1037.380475 1182.719165 1.074916253 0.984362445 0.955672899 1.090319735 0.850631883 1.419425874 1.199540117 1.154163317 0.877114793 1 10.20789183 -5.261217183 25 1.019650165 1.251892797 0.597831022 0.101496658 10.27158702 1155586.175 0.012304004 0.029349093 5.48E-06 5.261217183 0.232242633 EDEKGDDVDDPENQNSALADT(ph)DASGGLTKESPDTNGPK ddPTM_HeLa_Curcumin_4h_R1 1 EDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPK 38 2 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 EDEKGDDVDDPENQNS(0.167)ALADT(0.24)DAS(0.24)GGLT(0.094)KES(0.217)PDT(0.041)NGPK 69.142 1.44E-06 18240000 1689.2 1325.1 1527.4 1138.1 1484.9 2091.1 1589.1 1796.5 1845.6 1477.7 TRUE FALSE FALSE 1555.498038 1439.635739 1584.006788 1133.390844 1467.193537 1657.382288 1633.685869 2344.24458 1643.142297 1529.049965 1.017297062 0.941523019 1.03594181 0.741238592 0.959545843 1.083929451 1.068431972 1.533137983 1.074616484 1 10.57841984 -3.917137865 1.518417684 0.984952257 2.271621786 0.767261479 0.09081638 0.967603978 1.029270006 0.012585377 2.399485754 0.000121021 3.917137865 1.286669528 EDEKGDDVDDPENQNSALADTDASGGLT(ph)KESPDTNGPK ddPTM_HeLa_Curcumin_4h_R1 1 EDEKGDDVDDPENQNSALADTDASGGLTKESPDTNGPK 38 2 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 EDEKGDDVDDPENQNS(0.186)ALADT(0.186)DAS(0.186)GGLT(0.214)KES(0.214)PDT(0.014)NGPK 48.388 0.0038303 13307000 792.76 719.6 922.63 747.14 948.17 1250 809.91 986 1008.9 755.66 TRUE FALSE FALSE 730.0122095 781.7990175 956.8234794 744.0485326 936.863692 990.7359096 832.6338948 1286.626861 898.2261941 781.9191288 0.933616 0.999846389 1.223685985 0.951567119 1.198159321 1.267056749 1.06485935 1.645473059 1.148745645 1 9.610875592 -1 0.42593032 0.976454736 11.74870133 0.567639006 0.132326109 28.99322924 0.3279391 0.025909874 269.8542599 0.1 1 10.77224659 EDENDAS(ph)DDEDDDEKRR ddPTM_HeLa_Curcumin_4h_R1 1 EDENDASDDEDDDEKRR 17 2 Q9Y5B6-3;Q9Y5B6-4;Q9Y5B6-2;Q9Y5B6 Q9Y5B6-3 PAXBP1 PAX3- and PAX7-binding protein 1 1 0 EDENDAS(1)DDEDDDEKRR 99.569 0.0016342 8312200 2096.9 2135.8 2277.2 2461.9 2799.1 2364.5 1985 1866.9 2083.1 2318.9 TRUE FALSE FALSE 1930.928152 2320.409035 2361.595035 2451.71331 2765.722561 1874.076047 2040.693758 2436.109216 1854.589142 2399.481602 0.804727217 0.967045979 0.98421052 1.021767913 1.152633368 0.781033722 0.850472767 1.015264803 0.772912424 1 11.22850704 -7.103273383 18.43158972 0.906634044 0.965721608 0.124731934 0.111916649 11.36633458 2014.657799 0.019836551 0.024294827 7.88E-08 7.103273383 0.059087564 EDENSWFNLFVIHQNR ddPTM_HeLa_Curcumin_4h_R1 1 EDENSWFNLFVIHQNR 16 0 F8W7U8;P49959-2;P49959;P49959-3;F5GXT0 F8W7U8 MRE11A Double-strand break repair protein MRE11A 0 0 148.18 0.00028612 5182200 1158 925.06 1237 1170.8 1085.2 3032.2 1663.7 1787.4 1293.9 1230.1 FALSE FALSE TRUE 1066.343078 1005.018064 1282.844308 1165.95554 1072.259699 2403.28754 1710.378944 2332.370032 1151.962407 1272.845883 0.837762915 0.789583466 1.007855173 0.916022556 0.842411256 1.888121391 1.343743942 1.832405684 0.905028977 1 10.31384203 -5.269267691 24.99839736 0.912707894 1.653655705 0.852236117 0.150143927 147.2375537 470178.8086 0.020011473 0.045521208 5.38E-06 5.269267691 0.740947812 EDEVEEWQHR ddPTM_HeLa_Curcumin_4h_R1 3 EDEVEEWQHR 10 0 E7EQR4;P15311 E7EQR4 EZR Ezrin 0 0 ;; ;; 187.16 0.00013177 36182000 17623 15682 16992.4 17614.9 21185.3 20749.2 16163.2 16108.5 17993.6 13783.6 FALSE FALSE TRUE 16228.12095 17037.4822 17622.15329 17542.01421 20932.67913 16445.58203 16616.69589 21019.9075 16019.7471 14262.57907 1.137811112 1.194558299 1.235551663 1.229932828 1.46766437 1.153058079 1.165055479 1.47378026 1.123201282 1 13.79994726 -7.575096962 0.418971312 0.994601605 1.315927644 0.418606203 0.107486307 0.54078309 0.25560988 0.061402969 0.05360698 2.66E-08 7.575096962 0.321326039 EDFDSTSSSSS(ph)TPPLQPR ddPTM_HeLa_Curcumin_4h_R1 1 EDFDSTSSSSSTPPLQPR 18 0 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 0 EDFDST(0.038)S(0.014)S(0.001)S(0.005)S(0.046)S(0.448)T(0.448)PPLQPR 221.34 2.47E-17 11403000 1718.7 1457 1633.6 1332.3 1858.7 1681.6 1457.1 898.48 1452.8 1279.7 TRUE FALSE FALSE 1582.663081 1582.936588 1694.142653 1326.787296 1836.536216 1332.817204 1497.982304 1172.422416 1293.431475 1324.16948 1.195211871 1.19541842 1.279400167 1.001976949 1.38693441 1.006530678 1.131261766 0.885402083 0.976786956 1 10.37087207 -4.260177243 23.48017106 1.123144028 0.885401922 0.240225727 0.130134387 52.76402696 981307.3707 0.017425892 0.143982349 5.49E-05 4.260177243 -0.237742107 EDFDSTSSSSST(ph)PPLQPR ddPTM_HeLa_Curcumin_4h_R1 1 EDFDSTSSSSSTPPLQPR 18 0 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 0 EDFDSTSSSSS(0.084)T(0.915)PPLQPR 249.54 2.51E-33 14533000 1515.1 1447.3 1369.6 1421.6 1606 1574.8 1338.3 766.66 1401.6 1106.8 TRUE FALSE FALSE 1395.178236 1572.398163 1420.358581 1415.717796 1586.849499 1248.168728 1375.849096 1000.411105 1247.847987 1145.261218 1.218218355 1.372960281 1.240204906 1.236152743 1.385578656 1.089855056 1.20134086 0.873522206 1.089574996 1 10.16146098 -9.05668883 0.9607309 1.006459758 1.210294957 0.157996861 0.139151203 0.582302174 1.013751286 0.075593777 0.0257376 8.78E-10 9.05668883 0.203835199 EDFSGYDFENR ddPTM_HeLa_Curcumin_4h_R1 2 EDFSGYDFENR 11 0 G3V1P2;Q8N584-2;Q8N584 G3V1P2 TTC39C Tetratricopeptide repeat protein 39C 0 0 ; ; 143.4 0.0096092 10986900 2588.2 2350.4 2359.5 2643.4 2297.9 2351.6 1753.87 2238.78 2666.1 2196 FALSE FALSE TRUE 2383.341239 2553.558103 2446.945146 2632.462311 2270.499043 1863.851652 1803.078872 2921.373716 2373.6355 2272.310837 1.04886233 1.123771476 1.076853178 1.15849569 0.999202665 0.820245022 0.793500098 1.285640005 1.044591023 1 11.14994448 -5.519683174 24.99249098 1.04630412 0.942591925 0.09429746 0.132873646 211.460005 1653818.825 0.018371968 0.037341211 3.02E-06 5.519683174 -0.103712195 EDGGT(ph)VGVFSPK ddPTM_HeLa_Curcumin_4h_R1 1 EDGGTVGVFSPK 12 0 O43896 O43896 KIF1C Kinesin-like protein KIF1C 1 0 EDGGT(0.99)VGVFS(0.01)PK 145.29 0.0025024 14156000 7473 6847.6 6458.1 6843.2 7028.3 8472.6 6086.8 5083.1 7810.2 5985.7 TRUE FALSE FALSE 6881.504165 7439.476032 6697.442867 6814.884652 6944.492113 6715.287254 6257.579226 6632.91379 6953.4406 6193.702629 1.111048524 1.201135488 1.081331034 1.100292516 1.1212182 1.084212087 1.010313152 1.070912536 1.122662972 1 12.5965864 -9.192665767 1.032750581 1.002264361 1.097647635 0 0.058318054 0.434501647 0.860482077 0.028559832 0.008845664 6.42E-10 9.192665767 0.095383274 EDGGTVGVFS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 EDGGTVGVFSPK 12 0 O43896 O43896 KIF1C Kinesin-like protein KIF1C 1 0 EDGGT(0.019)VGVFS(0.981)PK;EDGGT(0.47)VGVFS(0.53)PK;EDGGT(0.116)VGVFS(0.884)PK ;; 134.4 0.0019048 74621000 11707.7 9069.7 10516 10625.9 10902.9 13779.3 10723.3 8064.9 12822.9 9769.2 TRUE FALSE FALSE 10781.02319 9853.644454 10905.73221 10581.93284 10772.89004 10921.31786 11024.16694 10523.85088 11416.25995 10108.67897 1.066511581 0.974770737 1.078848407 1.046816589 1.06570701 1.080390216 1.09056455 1.041070837 1.12935231 1 13.30330685 -13.52287875 0.171377573 0.765954036 1.074825808 0 0.04979261 47.85400403 0.533532801 3.775372964 0.046831288 3.00E-14 13.52287875 0.308871773 EDGLAQQQTQLNLR ddPTM_HeLa_Curcumin_4h_R1 1 EDGLAQQQTQLNLR 14 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 0 160.18 0.00043292 1145800 385.65 258.9 245.18 405.22 276.06 343.91 287.71 413.95 458.08 458.26 FALSE FALSE TRUE 355.1253956 281.2781624 254.2665865 403.543307 272.7681648 272.5791893 295.7823683 540.1614494 407.8297701 474.1845009 0.748918185 0.593182953 0.536218679 0.851025932 0.575236357 0.57483783 0.623770637 1.139137716 0.860065585 1 8.889304698 -8.641709036 0.807529861 0.985040793 0.689437669 0.19096479 0.176189663 0.517191548 0.678889784 0.07996133 0.035741177 2.28E-09 8.641709036 -0.295603123 EDGNEEDK(ac)ENQGDETQGQQPPQRR ddPTM_HeLa_Curcumin_4h_R1 2 EDGNEEDKENQGDETQGQQPPQRR 24 2 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 1 ; EDGNEEDK(1)ENQGDETQGQQPPQRR;EDGNEEDK(1)ENQGDETQGQQPPQRR 92.95 2.73E-05 1926910 0 0 0 0 0 72.862 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 57.74959988 0 0 0 0 0 EDGNEEDKENQGDETQGQQPPQR ddPTM_HeLa_Curcumin_4h_R1 2 EDGNEEDKENQGDETQGQQPPQR 23 1 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 0 ; ; 162.44 1.11E-06 2366100 849.6 722.53 511.86 618.29 681.33 794.44 540.12 528.1 513.49 369.92 FALSE FALSE TRUE 782.3532635 784.9822737 530.8299819 615.7316798 673.2055847 629.6641888 555.2743135 689.1152589 457.1614317 382.7746925 2.043900182 2.050768478 1.386794875 1.608600809 1.758751553 1.644999529 1.450655763 1.800315623 1.194335573 1 8.580351638 -9.471832936 1.222419064 1.001739843 1.739140662 0.570215044 0.213403085 0.261462553 0.701603744 0.160213304 0.039790574 3.37E-10 9.471832936 0.737400819 EDGNEEDKENQGDETQGQQPPQRR ddPTM_HeLa_Curcumin_4h_R1 4 EDGNEEDKENQGDETQGQQPPQRR 24 2 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 0 ;;; ;;; 102.47 4.22E-06 29129200 6218.9 5492.4 5284.6 5962.7 5580.4 6406.3 5284.7 5247.1 6778.4 5545.9 FALSE FALSE TRUE 5726.667503 5967.138582 5480.451925 5938.027927 5513.857375 5077.561166 5432.974459 6846.916635 6034.826479 5738.619612 0.99791725 1.039821244 0.955012232 1.034748481 0.960833397 0.884805321 0.946738907 1.19312955 1.051616397 1 12.48648803 -6.750579256 24.94831022 1.002049359 0.988769551 0 0.078915826 1517.585016 3486243.373 0.011725785 0.016477636 1.78E-07 6.750579256 -0.013279808 EDGRSSS(ph)GPPHETAAPK ddPTM_HeLa_Curcumin_4h_R1 1 EDGRSSSGPPHETAAPK 17 1 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 EDGRS(0.316)S(0.316)S(0.367)GPPHETAAPK 70.451 0.007211 11163000 5375 3725.2 3725.6 3540.8 6772.3 11800 6490 1123.2 7006 3659.5 TRUE FALSE FALSE 4949.563078 4047.189689 3863.674013 3526.149108 6691.544746 9352.546987 6672.091933 1465.658509 6237.459328 3786.667353 1.307102689 1.0687999 1.020336262 0.93120118 1.767132975 2.469862313 1.76199579 0.387057635 1.647216073 1 11.88671298 -5.755683449 24.99446617 1.11829159 1.670714667 0.135038001 0.517734732 163.4527758 709767.4211 0.070652242 0.138279291 1.76E-06 5.755683449 0.552423076 EDGTFYEFGEDIPEAPER ddPTM_HeLa_Curcumin_4h_R1 2 EDGTFYEFGEDIPEAPER 18 0 O43776 O43776 NARS "Asparagine--tRNA ligase, cytoplasmic" 0 0 ; ; 245.4 2.90E-31 19687000 1474.13 1599.5 1490.56 1844.04 1910.93 1961.49 1599.95 1397.4 1667.67 1528.87 FALSE FALSE TRUE 1357.451055 1737.753653 1545.801465 1836.409851 1888.143408 1554.654863 1644.840291 1823.460827 1484.730773 1581.998119 0.858061106 1.098454943 0.977119661 1.16081671 1.193518112 0.982716 1.039723291 1.152631476 0.938516143 1 10.62753217 -7.246777956 24.95620988 0.9329733 1.083416712 0.468430775 0.075242186 567.7078717 966335.1987 0.014087078 0.017214216 5.67E-08 7.246777956 0.150443412 EDGVLGSRS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 EDGVLGSRSPR 11 1 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312;D6RFZ4;P78312-3 E7EUR8 FAM193A Protein FAM193A 1 0 EDGVLGS(0.074)RS(0.926)PR;EDGVLGS(0.022)RS(0.978)PR ; 100.82 0.0046295 12520100 8120 7311 7784.8 7328.9 7778.4 7690.9 4618.6 3049 7770.8 7422.8 TRUE FALSE FALSE 7477.293432 7942.930263 8073.311536 7298.574954 7685.64766 6095.720646 4748.185486 3978.626064 6918.362682 7680.741747 0.973511892 1.034135833 1.051110922 0.950243504 1.000638729 0.793636975 0.618193612 0.518000239 0.900741479 1 12.90702993 -4.881169147 1.672826363 0.995411133 0.51605251 0.940711147 0.042383359 0.048123025 0.241436036 0.004504035 0.025272808 1.31E-05 4.881169147 -0.479358622 EDILENEDEQNS(ph)PPKK ddPTM_HeLa_Curcumin_4h_R1 1 EDILENEDEQNSPPKK 16 1 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 EDILENEDEQNS(1)PPKK 59.261 0.020082 5751800 2217.5 1975.5 2489.6 2752.8 2869.3 2885.3 2314.3 1784 2187 2340.1 TRUE FALSE FALSE 2041.982535 2146.253417 2581.866766 2741.409643 2835.085472 2286.856256 2379.233029 2327.933387 1947.091572 2421.418301 0.843300199 0.886362103 1.066262184 1.132150377 1.170836724 0.944428418 0.98257828 0.961392497 0.804112024 1 11.24163661 -6.757540638 24.99939728 0.920962245 1.045588158 0.434671295 0.084870255 96.52889949 618956.4186 0.014816082 0.020506578 1.75E-07 6.757540638 0.124625913 EDIYSGGGGGGSR ddPTM_HeLa_Curcumin_4h_R1 2 EDIYSGGGGGGSR 13 0 Q13151 Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0 0 0 ; ; 163.9 2.36E-05 4108900 1301.11 1227.74 1319.92 1269.82 1225.66 1598.55 1290.49 820.25 1352.03 1134.39 FALSE FALSE TRUE 1198.125771 1333.860375 1368.837396 1264.565821 1211.044805 1266.992711 1326.697676 1070.340449 1203.715692 1173.809968 1.02071528 1.136351208 1.166149065 1.07731733 1.03172135 1.079384862 1.130249114 0.911851559 1.025477483 1 10.19698315 -7.440657068 8.290296727 1.009082559 1.080190544 0.147812671 0.066406605 0.387360989 35.86420743 0.010944761 0.012470067 3.63E-08 7.440657068 0.071107985 EDKNGHDGDTHQEDDGEKS(ph)D ddPTM_HeLa_Curcumin_4h_R1 2 EDKNGHDGDTHQEDDGEKSD 20 2 K7EQH5;Q08117;Q08117-2 K7EQH5 AES Amino-terminal enhancer of split 1 0 EDKNGHDGDTHQEDDGEKS(1)D;EDKNGHDGDTHQEDDGEKS(1)D ; 69.649 0.0019346 42401000 6979.2 9075.4 8169.8 6800.6 7082.8 7795.7 3963.4 3700.4 7267.7 8674.2 TRUE FALSE FALSE 6426.788956 9859.837137 8472.579975 6772.460919 6998.342236 6178.783944 4074.602337 4828.634925 6470.451493 8975.627804 0.716026678 1.098512255 0.943954023 0.754538966 0.77970504 0.68839574 0.453962935 0.537971831 0.720891244 1 13.13179714 -5.155765136 1.159942604 0.884878631 0.470094705 0.606963186 0.11847259 0.328779791 0.74690041 0.02071038 0.110897763 6.99E-06 5.155765136 -0.414783926 EDKS(ph)PETGTAGGSSTASYSAGR ddPTM_HeLa_Curcumin_4h_R1 2 EDKSPETGTAGGSSTASYSAGR 22 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 EDKS(0.937)PET(0.059)GT(0.004)AGGSSTASYSAGR;EDKS(0.986)PET(0.013)GT(0.001)AGGSSTASYSAGR ; 127.16 4.67E-06 48024000 2796.1 2879.3 2912.5 2577.4 3191.8 2256.31 2467.62 2671.07 2727.6 2546.27 TRUE FALSE FALSE 2574.785735 3128.173862 3020.439812 2566.735402 3153.73987 1788.325872 2536.854776 3485.466947 2428.389104 2634.752693 0.977240005 1.187274187 1.146384562 0.974184563 1.196977568 0.678745249 0.962843603 1.322882013 0.921676296 1 11.36345184 -11.05460808 0.008727579 0.000159297 1.967147083 0.030904153 0.169909752 39216.21926 45.914036 5569.091856 4802.941244 8.82E-12 11.05460808 1.966987786 RRVS(ph)EVEEEKEPVPQPLPSDDTR ddPTM_HeLa_Curcumin_4h_R1 3 RRVSEVEEEKEPVPQPLPSDDTR 23 3 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 1 0 RRVS(1)EVEEEKEPVPQPLPSDDTR;RRVS(1)EVEEEKEPVPQPLPSDDTR;RRVS(1)EVEEEKEPVPQPLPSDDTR ;; 53.96 0.0064374 154035000 5611.6 4460.31 5067.7 4970.2 6163.4 4766.8 5658.4 8071 5010.8 4383.4 TRUE FALSE FALSE 5167.435939 4845.839322 5255.51342 4949.634629 6089.90548 3778.111947 5817.159475 10531.81075 4461.127776 4535.722824 1.13927507 1.068372013 1.158693691 1.091255974 1.342653799 0.832967995 1.282520935 2.321969652 0.983553879 1 12.14711677 -4.279002783 3.553300274 1.082154143 2.445165905 0.896526628 0.126118139 0.053164626 1.191527094 0.016051114 0.187805094 5.26E-05 4.279002783 1.363011761 up EDKSPSEESAPTT(ph)SPESVSGSVPSSGSSGR ddPTM_HeLa_Curcumin_4h_R1 3 EDKSPSEESAPTTSPESVSGSVPSSGSSGR 30 1 P54725-2;P54725-3;P54725;A0A494C0B4 P54725-2 RAD23A UV excision repair protein RAD23 homolog A 1 0 EDKSPSEESAPTT(0.499)S(0.499)PES(0.001)VSGSVPSSGSSGR;EDKSPSEESAPT(0.001)T(0.935)S(0.064)PESVSGSVPSSGSSGR;EDKSPSEESAPT(0.016)T(0.491)S(0.491)PES(0.002)VSGSVPSSGSSGR ;; 163.72 1.01E-14 204227600 3715.95 3098.69 3338.68 3068.52 3379.54 4267.93 3297.05 2966.97 2707.61 2557.19 TRUE FALSE FALSE 3421.828636 3366.526956 3462.414418 3055.823277 3339.241193 3382.713209 3389.556349 3871.585495 2410.591957 2646.052162 1.293182608 1.272282914 1.308520848 1.154861314 1.261971038 1.278400047 1.280986217 1.463155394 0.911014526 1 11.36962579 -12.4788832 0.244257641 1.03E-10 1.321227359 0.770124131 0.07302771 11.40478274 0.235158575 5.51390191 0.046521353 3.32E-13 12.4788832 1.321227359 EDLPAENGETKTEESPAS(ph)DEAGEK ddPTM_HeLa_Curcumin_4h_R1 1 EDLPAENGETKTEESPASDEAGEK 24 1 P05114;A6NL93;A6NEL0 P05114 HMGN1 Non-histone chromosomal protein HMG-14 1 0 EDLPAENGET(0.001)KT(0.002)EES(0.318)PAS(0.679)DEAGEK 70.959 0.00041315 8820900 2091.9 1957 2149.2 1875.8 2586.8 2210.1 2314 2148 1517.7 1648.5 TRUE FALSE FALSE 1926.323908 2126.15436 2228.851243 1868.038437 2555.954099 1751.700347 2378.924612 2802.915312 1351.212107 1705.785252 1.12928864 1.246437297 1.306642345 1.09511935 1.498403211 1.026917277 1.394621397 1.643181818 0.792134945 1 10.73622032 -1 0.158724005 0.957892609 3.030969519 0.546804659 0.163159956 36.54190731 0.367829857 0.255639396 17.75942623 0.1 1 2.07307691 EDLRLPEGDLGK ddPTM_HeLa_Curcumin_4h_R1 1 EDLRLPEGDLGK 12 1 I3L397;I3L504;P63241;P63241-2 I3L397 EIF5A Eukaryotic translation initiation factor 5A;Eukaryotic translation initiation factor 5A-1 0 0 103.43 0.006496 33962000 7799.4 7320.8 7711.3 5952.4 8738.5 10429 8421.5 7979.3 6372.3 5558.3 FALSE FALSE TRUE 7182.06926 7953.577331 7997.087562 5927.770546 8634.299095 8265.907841 8657.784625 10412.15184 5673.274633 5751.450511 1.248740513 1.38288199 1.390447079 1.03065662 1.501238527 1.437186641 1.505321937 1.810352331 0.986407624 1 12.48971013 -1 0.144744716 0.938374817 3.609902333 0.718510629 0.133368961 29.11784401 0.275668575 0.324451951 16.27339766 0.1 1 2.671527516 EDLSPAFDHS(ph)PNK ddPTM_HeLa_Curcumin_4h_R1 2 EDLSPAFDHSPNK 13 0 K7EIY0;K7ENP9;K7EIE9;D3DUJ3;K7EQG9;P17706-3;P17706-2;P17706-4;P17706 K7EIY0 PTPN2 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 2 1 0 EDLSPAFDHS(1)PNK;EDLSPAFDHS(1)PNK ; 127.05 0.00087723 37036900 8584.7 8544.9 10212 8723.8 12802.7 11346.4 10493.3 4290.7 9221.8 8084 TRUE FALSE FALSE 7905.211936 9283.483081 10590.4657 8687.703227 12650.03616 8993.02874 10787.71376 5598.914678 8210.191612 8364.918398 0.945043521 1.109811553 1.266057264 1.038587923 1.512272513 1.075088639 1.289637656 0.669332851 0.981502894 1 13.03013575 -7.139483839 4.552465122 0.974312898 1.15960073 0.113617346 0.204162551 0.307871757 10.17841879 0.031424161 0.038735745 7.25E-08 7.139483839 0.185287832 EDLVGPEVGAS(ph)PQSGR ddPTM_HeLa_Curcumin_4h_R1 2 EDLVGPEVGASPQSGR 16 0 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 0 EDLVGPEVGAS(0.504)PQS(0.496)GR;EDLVGPEVGAS(0.906)PQS(0.094)GR ; 152.66 0.00033375 17372900 6349.7 5096.4 6609.2 6267.6 8040.4 6576 5491.7 1827.87 5016.5 4735.9 TRUE FALSE FALSE 5847.114545 5536.910107 6854.142766 6241.666332 7944.523481 5212.063473 5645.782322 2385.179149 4466.202501 4900.472172 1.193173706 1.129872778 1.398669868 1.273686721 1.621175103 1.063583934 1.152089457 0.486724353 0.911382076 1 12.25870505 -4.260246618 6.016960071 1.165301592 0.468226864 0.539304947 0.194479711 0.084778604 14.71713205 0.027388259 0.239459459 5.49E-05 4.260246618 -0.697074727 TELESTIFGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 TELESTIFGSPR 12 0 Q9UQK1 Q9UQK1 PPP1R3C Protein phosphatase 1 regulatory subunit 3C 1 0 TELES(0.001)T(0.001)IFGS(0.998)PR;TELESTIFGS(1)PR;TELESTIFGS(1)PR ;; 190.35 5.70E-06 18255700 5981.5 5460.7 5051.2 5222.7 4787.4 6087.4 2766.2 1789.28 6792.2 4605.6 TRUE FALSE FALSE 5508.057963 5932.698576 5238.401915 5201.089851 4730.313382 4824.804621 2843.812127 2334.823235 6047.112653 4765.644257 1.155784542 1.244889097 1.099201206 1.091371821 0.992586338 1.012413928 0.596731937 0.489928142 1.2688972 1 12.21845555 -4.738358756 2.282184897 1.087148668 0.47876194 0.864731139 0.089902453 0.080403745 0.789061224 0.012256744 0.065998054 1.83E-05 4.738358756 -0.608386728 down EDLYLK(ac)PIQR ddPTM_HeLa_Curcumin_4h_R1 2 EDLYLKPIQR 10 1 P13639 P13639 EEF2 Elongation factor 2 0 1 ; EDLYLK(1)PIQR;EDLYLK(1)PIQR 152.28 8.36E-07 19326200 2900.3 3780.1 3229 2965.9 5661.3 6449.1 4819.9 4778.4 5062.5 2616 FALSE TRUE FALSE 2670.738195 4106.835 3348.669581 2953.627892 5593.792695 5111.483964 4955.133422 6235.312163 4507.156416 2706.905805 0.986638763 1.517169527 1.237083896 1.091145427 2.0664896 1.888312461 1.830552586 2.303483243 1.665058462 1 11.40242897 -5.628933911 0.556496659 0.981150602 2.297929069 0.51012474 0.31062021 0.407223489 0.191985117 0.049101883 0.267467317 2.35E-06 5.628933911 1.316778467 EDLYLKPIQR ddPTM_HeLa_Curcumin_4h_R1 2 EDLYLKPIQR 10 1 P13639 P13639 EEF2 Elongation factor 2 0 0 ; ; 104.01 0.0034302 18436900 13373.3 11758.2 13335.7 12651.2 14449.5 14672.5 11841.8 10788.3 12588.2 11496.2 FALSE FALSE TRUE 12314.78919 12774.52641 13829.93277 12598.85269 14277.19915 11629.25811 12174.04904 14077.60301 11207.30595 11895.69209 1.035230998 1.073878368 1.162600096 1.059110524 1.200199117 0.977602481 1.023399811 1.183420258 0.942131476 1 13.53815159 -7.360649247 2.155337882 1.013833718 1.095625877 0.311700807 0.070158381 0.327668188 2.885741142 0.011891681 0.013594565 4.36E-08 7.360649247 0.081792158 EDMAALEK ddPTM_HeLa_Curcumin_4h_R1 2 EDMAALEK 8 0 Q9BQE3;F5H5D3;P68363;P68363-2;P68366-2;P68366 Q9BQE3;P68363;P68366-2 TUBA1C;TUBA1B;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 0 ; ; 122.52 0.0024531 26823000 16121.7 14543.8 16193.7 13880.7 19057.6 15206.1 12924.2 12987.3 12200.7 12600.3 FALSE FALSE TRUE 14845.65043 15800.90127 16793.85277 13823.26534 18830.35057 12052.18345 13286.81827 16947.06798 10862.31373 13038.15949 1.138630836 1.211896609 1.288053945 1.060216003 1.444249135 0.924377667 1.019071617 1.299805237 0.833117109 1 13.67045261 -8.645837851 0.833359692 1.009301785 1.169795517 0.266543089 0.153964034 0.756008798 1.05736346 0.063886003 0.029129824 2.26E-09 8.645837851 0.160493732 EDMAALEKDYEEVGADS(ph)ADGEDEGEEY ddPTM_HeLa_Curcumin_4h_R1 3 EDMAALEKDYEEVGADSADGEDEGEEY 27 1 Q9BQE3;F5H5D3 Q9BQE3 TUBA1C Tubulin alpha-1C chain 1 0 EDMAALEKDYEEVGADS(0.982)ADGEDEGEEY(0.018);EDMAALEKDYEEVGADS(0.999)ADGEDEGEEY(0.001);EDMAALEKDYEEVGADS(0.999)ADGEDEGEEY(0.001) ;; 114.84 3.63E-09 26986000 20947.9 16814.9 18181.9 18777.9 17972 22170.8 17498.2 20574.3 21216 18343.1 TRUE FALSE FALSE 19289.85161 18268.30503 18855.73721 18700.20203 17757.69564 17572.32616 17989.1524 26847.30936 18888.65788 18980.52136 1.016297247 0.962476461 0.993425673 0.98523121 0.935574703 0.925808403 0.94776914 1.414466381 0.995160118 1 14.212232 -4.258051159 24.99589305 0.989112059 1.41446654 0.944158046 0.031968939 64.43138547 475307.0982 0.005336929 0.052008064 5.52E-05 4.258051159 0.425354481 EDMAALEKDYEEVGADSADGEDEGEEY ddPTM_HeLa_Curcumin_4h_R1 5 EDMAALEKDYEEVGADSADGEDEGEEY 27 1 Q9BQE3;F5H5D3 Q9BQE3 TUBA1C Tubulin alpha-1C chain 0 0 ;;;; ;;;; 160.3 7.89E-10 278266000 59464.9 48663.6 51038.8 54252.8 52162.6 59234.8 46399.8 47570.5 56292.3 48661 FALSE FALSE TRUE 54758.19042 52869.86474 52930.34283 54028.31629 51540.59506 46948.83477 47701.65351 62074.52646 50117.17553 50351.96613 1.087508485 1.050005964 1.051207071 1.073013041 1.023606406 0.932413138 0.947364268 1.232812365 0.995337012 1 15.61976049 -5.556480786 23.88436199 1.045913278 1.020096057 0 0.080871352 443.5519366 315275.8512 0.011398652 0.022797518 2.78E-06 5.556480786 -0.025817221 EDMAALEKDYEEVGVDSVEGEGEEEGEEY ddPTM_HeLa_Curcumin_4h_R1 4 EDMAALEKDYEEVGVDSVEGEGEEEGEEY 29 1 P68363;P68363-2 P68363 TUBA1B Tubulin alpha-1B chain 0 0 ;;; ;;; 156.23 3.77E-13 116880000 57587.6 44136.4 46805.8 51265.2 49669.3 58396.5 43864.2 44320.9 54373.9 48188.2 FALSE FALSE TRUE 53029.48069 47951.35375 48540.46412 51053.07819 49077.02604 46284.40764 45094.9114 57834.13838 48409.21921 49862.73636 1.063509237 0.961667113 0.973481755 1.023872373 0.984242535 0.928236415 0.904381 1.159866919 0.970849631 1 15.60567444 -7.253695222 24.93756157 1.029990473 0.985440709 0 0.069263783 1058.063403 3407161.714 0.010817739 0.01312061 5.58E-08 7.253695222 -0.044549765 EDPGSGVRVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 EDPGSGVRVSPK 12 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 EDPGS(0.006)GVRVS(0.994)PK 66.56 0.018192 19429000 5639 4964.2 5543 4956.3 6075.2 5912.2 4299.8 2817.1 6088.9 4762.3 TRUE FALSE FALSE 5192.6672 5393.283328 5748.428456 4935.792144 6002.757208 4685.943076 4420.440816 3676.020822 5420.962904 4927.789571 1.053751814 1.094462994 1.166532859 1.001623968 1.218143982 0.950921911 0.89704334 0.745977637 1.100080031 1 12.26672494 -4.598809761 1.923660547 1.051265401 0.745790573 0.668017213 0.075006145 0.216988656 1.303950408 0.010834042 0.092537582 2.52E-05 4.598809761 -0.305474828 EDQSILCTGESGAGK ddPTM_HeLa_Curcumin_4h_R1 1 EDQSILCTGESGAGK 15 0 P35579;P35579-2;Q5BKV1;Q7Z406-5;Q7Z406-4;E7ERA5;A0A494C024;M0QY43;A0A2R8Y4C3;P35580;P35580-5;P35580-2;P35580-3;P35580-4;P35749-4;P35749-3;P35749;P35749-2;Q7Z406;Q7Z406-6;Q7Z406-2 P35579;P35580;P35749-4;Q7Z406 MYH9;MYH14;MYH10;MYH11 Myosin-9;Myosin-14;Myosin-10;Myosin-11 0 0 281.51 1.97E-93 2205000 901.55 973.6 1008.5 877.33 1251.2 995.05 793.67 777.44 674.65 771.4 FALSE FALSE TRUE 830.1913662 1057.753646 1045.875897 873.6998409 1236.280257 788.6654135 815.9382441 1014.477877 600.6425829 798.2060926 1.040071448 1.325163583 1.31028303 1.094579268 1.548823379 0.988047349 1.022215004 1.270947299 0.752490602 1 9.640617481 -7.379867084 6.509944359 1.017640924 1.216779575 0.335900687 0.175939632 0.240394417 12.01665561 0.025925499 0.029534841 4.17E-08 7.379867084 0.199138651 EDQTEYLEER ddPTM_HeLa_Curcumin_4h_R1 3 EDQTEYLEER 10 0 P08238;Q58FF7;Q58FF6;P07900;P07900-2;G3V2J8 P08238;P07900 HSP90AB1;HSP90AB3P;HSP90AB4P;HSP90AA1 Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-alpha 0 0 ;; ;; 202.96 2.53E-26 316696000 7723 7052.7 7434 7188.7 9333 8551.4 7429.7 7104.7 6029.7 6285.7 FALSE FALSE TRUE 7111.716401 7662.303962 7709.51058 7158.955064 9221.710071 6777.743246 7638.157386 9270.890324 5368.256996 6504.127607 1.093415878 1.178067902 1.185325849 1.100678753 1.417824284 1.042068 1.174355401 1.425385676 0.825361573 1 12.66713985 -1 0.078129856 0.793901206 2.131093698 0.501201227 0.121311616 126.1461201 0.727037507 1.978137174 18.35955195 0.1 1 1.337192491 EDQTEYLEERR ddPTM_HeLa_Curcumin_4h_R1 4 EDQTEYLEERR 11 1 P08238;Q58FF7;P07900;P07900-2;G3V2J8 P08238;P07900 HSP90AB1;HSP90AB3P;HSP90AA1 Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Heat shock protein HSP 90-alpha 0 0 ;;; ;;; 153.74 0.0001932 72956400 10552.1 8201 8747.7 8640.8 7864.2 10808.1 7476.66 8615.8 10004.6 9085.7 FALSE FALSE TRUE 9716.89015 8909.857897 9071.897457 8605.046659 7770.424551 8566.378228 7686.434957 11242.71776 8907.12041 9401.427399 1.033554772 0.947713312 0.964948946 0.915291508 0.826515403 0.911178469 0.817581696 1.195852213 0.947422134 1 13.1986641 -6.961413847 1.917147042 1.015690773 0.923202741 0.029387625 0.101093942 0.446727712 3.278976085 0.016121604 0.021442128 1.09E-07 6.961413847 -0.092488032 EDS(ph)FESLDSLGSR ddPTM_HeLa_Curcumin_4h_R1 2 EDSFESLDSLGSR 13 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;E9PMP7 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 EDS(1)FESLDSLGSR;EDS(0.995)FES(0.005)LDSLGSR ; 203.85 6.76E-09 70287000 4383.7 3589.9 3681.8 4231.8 3984.4 4880.1 4738.3 5300.1 4172.9 4147.8 TRUE FALSE FALSE 4036.725519 3900.19496 3818.250747 4214.289933 3936.888632 3867.91225 4871.243946 6916.076091 3715.14331 4291.935741 0.940537269 0.908726317 0.889633717 0.981908907 0.917275763 0.901204604 1.134975973 1.611411845 0.865610189 1 12.06741276 -4.304617528 2.549779688 0.954230207 1.717157856 0.948520965 0.04806605 0.066087714 0.578294153 0.006460281 0.103502685 4.96E-05 4.304617528 0.76292765 AAAGPLDMS(ph)LPS(ph)TPDIK ddPTM_HeLa_Curcumin_4h_R1 1 AAAGPLDMSLPSTPDIK 17 0 K7ELQ4;P17544-4;P17544-2;P17544 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 2 0 AAAGPLDMS(0.998)LPS(0.995)T(0.006)PDIK 122.1 0.00067085 9780200 2306.5 1967.3 2023.8 2044 2371.6 2186.7 2715.7 4244.8 2434.2 1957.3 TRUE FALSE FALSE 2123.938091 2137.344646 2098.803808 2035.54247 2343.320219 1733.153771 2791.895233 5539.019979 2167.17435 2025.316029 1.048694653 1.055314141 1.036284599 1.005049306 1.157014602 0.855744854 1.378498562 2.734891691 1.070042561 1 10.98393133 -4.278786681 2.886216268 1.026479462 2.998485611 0.978561426 0.075543974 0.031202827 0.373218992 0.009033513 0.140200296 5.26E-05 4.278786681 1.972006149 up EDS(ph)PGPEVQPMDK ddPTM_HeLa_Curcumin_4h_R1 1 EDSPGPEVQPMDK 13 0 O75382-3;O75382-2;O75382;E9PMW5;E9PMK8 O75382-3 TRIM3 Tripartite motif-containing protein 3 1 0 EDS(1)PGPEVQPMDK 181.75 0.00012356 4406100 1176.5 1273.9 1421.3 1169.6 1215.8 1247.5 1144.1 1105.1 1243.8 1220.6 TRUE FALSE FALSE 1083.378784 1384.01024 1473.974628 1164.760505 1201.302379 988.7544378 1176.200367 1442.039903 1107.358252 1263.015759 0.85777139 1.095798077 1.167027899 0.922205837 0.951138076 0.78285202 0.931263413 1.141743397 0.876757272 1 10.30265692 -4.258185088 23.85336608 0.948496047 1.141743532 0.216659213 0.106731999 206.6814828 1514791.76 0.01561382 0.148702317 5.52E-05 4.258185088 0.193247486 EDSAPPSS(ph)VAR ddPTM_HeLa_Curcumin_4h_R1 2 EDSAPPSSVAR 11 0 Q9BZE4-3;Q9BZE4-2;Q9BZE4 Q9BZE4-3 GTPBP4 Nucleolar GTP-binding protein 1 1 0 EDSAPPS(0.172)S(0.828)VAR;EDS(0.002)APPS(0.136)S(0.861)VAR ; 109.72 0.0064218 8970900 5666 5303.3 5780.2 6356.7 6000.7 7845.1 6662.3 3886.8 6910 6008.5 TRUE FALSE FALSE 5217.530121 5761.693621 5994.419297 6330.39766 5929.145572 6217.937828 6849.226207 5071.867427 6151.990288 6217.294928 0.839196175 0.926720332 0.964152315 1.01819163 0.953653581 1.000103405 1.101640872 0.815767546 0.989496294 1 12.6020713 -6.661617786 3.878856979 0.922104565 0.985057656 0.030764529 0.078809247 0.405136261 11.55813177 0.013532486 0.019309309 2.18E-07 6.661617786 0.062953091 EDSARPGAHAK(ac)VK ddPTM_HeLa_Curcumin_4h_R1 2 EDSARPGAHAKVK 13 2 Q13151 Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0 0 1 ; EDSARPGAHAK(1)VK;EDSARPGAHAK(1)VK 60.08 0.018387 3847300 7366.9 5132.8 5659 5435.1 7141.2 9453.6 6645.5 5906.4 7627.9 5989.2 FALSE TRUE FALSE 6783.802091 5576.456361 5868.727518 5412.610996 7056.045854 7492.816796 6831.954845 7707.23417 6791.138454 6197.324254 1.094634041 0.899816781 0.946977643 0.873378699 1.138563284 1.209040626 1.102403967 1.243639005 1.095817836 1 12.59742974 -5.543862603 24.65540211 1.014453346 1.17627158 0.567718878 0.078691293 136.0229136 159822.4223 0.012288506 0.024578974 2.86E-06 5.543862603 0.161818234 EDSGLFS(ph)PIR ddPTM_HeLa_Curcumin_4h_R1 2 EDSGLFSPIR 10 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 0 EDS(0.078)GLFS(0.922)PIR;EDS(0.002)GLFS(0.998)PIR ; 119.03 0.0047349 38156000 5432.3 4292 5380.8 4888.6 4970 5192.7 4224.8 3548.1 5933.7 4985.6 TRUE FALSE FALSE 5002.327723 4662.981355 5580.217181 4868.372269 4910.735996 4115.675486 4343.336518 4629.899357 5282.787955 5158.849229 0.969659608 0.903880138 1.081678672 0.943693458 0.951905314 0.797789449 0.841919646 0.897467468 1.024024491 1 12.33283357 -5.424774268 4.057861535 0.982988035 0.845893125 0.614425745 0.049950812 0.109448026 3.178022406 0.006625714 0.015304401 3.76E-06 5.424774268 -0.13709491 EDSGSS(ph)SPPGVFLEKDYEIYR ddPTM_HeLa_Curcumin_4h_R1 1 EDSGSSSPPGVFLEKDYEIYR 21 1 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 0 EDS(0.006)GS(0.104)S(0.489)S(0.4)PPGVFLEKDYEIYR 89.201 0.00024297 5104200 1093.4 999.95 1078.6 1130.4 1107.1 1375.1 1042 580 1406.3 1070.9 TRUE FALSE FALSE 1006.856236 1086.381222 1118.573865 1125.722704 1093.898556 1089.888759 1071.235716 756.83933 1252.032408 1108.113695 0.908621778 0.980387867 1.009439618 1.015890977 0.987171768 0.98355319 0.96672004 0.682997903 1.129877208 1 10.1138902 -4.261504823 7.838462515 0.969438679 0.680444488 0.702183599 0.058961604 0.030131331 20.86214573 0.005769465 0.045871602 5.48E-05 4.261504823 -0.288994191 GLVAAYSGESDS(ph)EEEQER ddPTM_HeLa_Curcumin_4h_R1 1 GLVAAYSGESDSEEEQER 18 0 P98175-5;P98175-2;P98175;P98175-4;P98175-3 P98175-5 RBM10 RNA-binding protein 10 1 0 GLVAAYS(0.026)GES(0.428)DS(0.546)EEEQER 144.73 0.00021123 5502300 790.2 876.32 620.06 713.57 789.04 785 966.75 1588.7 855.03 741.77 TRUE FALSE FALSE 727.6548362 952.065196 643.0399691 710.6174364 779.6312133 622.1821512 993.8744031 2073.087317 761.2353482 767.5464523 0.948027099 1.240400751 0.837786387 0.925829876 1.015744664 0.810611722 1.294871991 2.700927495 0.991777561 1 9.584110256 -4.274038908 3.024343155 0.975061855 2.953644459 0.954669897 0.112594829 0.0461917 0.629812616 0.014378531 0.21562061 5.32E-05 4.274038908 1.978582605 up EDSQRPGAHLTVK ddPTM_HeLa_Curcumin_4h_R1 1 EDSQRPGAHLTVK 13 1 F8W6I7;P09651-2;P09651;P09651-3;F8VZ49;Q32P51;F8VYN5;F8W646 F8W6I7 HNRNPA1;HNRNPA1L2 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;Heterogeneous nuclear ribonucleoprotein A1-like 2" 0 0 68.171 0.017707 9069000 5038.3 4815.3 4129 4111.2 9954.2 16042 7576.8 6577.1 8222.4 4670.1 FALSE FALSE TRUE 4639.513239 5231.513075 4282.024372 4094.188944 9835.502666 12714.70837 7789.384616 8582.427513 7320.423291 4832.385627 0.960087542 1.082594288 0.886109823 0.847239699 2.035330668 2.631145225 1.611912876 1.776022895 1.514867367 1 12.23851987 -5.757496849 24.99889921 0.972877295 2.02902115 0.702767543 0.305054842 31.47818153 199594.8078 0.036165599 0.07023093 1.75E-06 5.757496849 1.056143855 EDTEEHHLR ddPTM_HeLa_Curcumin_4h_R1 4 EDTEEHHLR 9 0 P22626;P22626-2;A0A087WUI2;F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8VZ49;A0A2R8Y4L2;Q32P51;F8VYN5 P22626;F8W6I7 HNRNPA2B1;HNRNPA1;HNRNPA1L2 "Heterogeneous nuclear ribonucleoproteins A2/B1;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;Heterogeneous nuclear ribonucleoprotein A1-like 2" 0 0 ;;; ;;; 134.05 0.00011035 73480160 18219.99 29091.1 18090.19 14754.23 17837.61 21557.4 16960.75 16196.23 11708.64 16944.62 FALSE FALSE TRUE 16777.85857 31605.60506 18760.62836 14693.18091 17624.90815 17086.15224 17436.623 21134.38597 10424.23149 17533.44428 0.95690603 1.802589642 1.069991044 0.838008817 1.005216537 0.974489208 0.994477908 1.205375603 0.594534155 1 14.09782181 EDTEEHHLRDYFEQYGK ddPTM_HeLa_Curcumin_4h_R1 3 EDTEEHHLRDYFEQYGK 17 1 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8VZ49;A0A2R8Y4L2;Q32P51;F8VYN5 F8W6I7 HNRNPA1;HNRNPA1L2 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;Heterogeneous nuclear ribonucleoprotein A1-like 2" 0 0 ;; ;; 113.43 0.00044195 60394900 23560.8 18323.2 15650.6 19931.8 12858.6 32415.1 20091.9 19950.9 29824.9 24474 FALSE FALSE TRUE 21695.93782 19906.97576 16230.625 19849.32749 12705.26959 25691.84287 20655.62464 26033.83757 26553.18309 25324.46968 0.856718348 0.786076708 0.640906807 0.783800322 0.501699335 1.014506649 0.815638981 1.028011165 1.048518821 1 14.62824444 -8.269274849 0.922535716 0.97862978 0.791565728 0.249566544 0.148870836 0.556038524 0.996121384 0.048457603 0.031519487 5.38E-09 8.269274849 -0.187064052 EDTEEYNLRDYFEK ddPTM_HeLa_Curcumin_4h_R1 1 EDTEEYNLRDYFEK 14 1 P51991;P51991-2 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 0 86.756 0.011155 8272600 1808.7 1762 1764.9 1893.9 1689 2826.9 1493.2 2045.1 2691.8 2061.2 FALSE FALSE TRUE 1665.539486 1914.299429 1830.308747 1886.063544 1668.859778 2240.569074 1535.095173 2668.641576 2396.516275 2132.826547 0.780907144 0.897541074 0.858161087 0.884302358 0.7824639 1.05051631 0.719746843 1.251222974 1.12363393 1 11.05855093 -4.243997558 24.24574655 0.885125136 1.25122343 0.42634313 0.121272228 1465.3661 2036946.447 0.01413869 0.549907008 5.70E-05 4.243997558 0.366098294 EDVDAAVK ddPTM_HeLa_Curcumin_4h_R1 1 EDVDAAVK 8 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 0 0 95.909 0.01296 0 2761.4 2049.4 2268 2250.2 2108.3 2928.4 2480.1 2618.8 2466.2 2168.6 FALSE FALSE TRUE 2542.832276 2226.541004 2352.054075 2240.889269 2083.159899 2321.01683 2549.684931 3417.260065 2195.66403 2243.958689 1.133190325 0.992237966 1.048171736 0.998632141 0.928341466 1.034340267 1.136244149 1.522871202 0.97847792 1 11.1318304 -4.262663784 2.696635138 1.04262144 1.616409546 0.876714406 0.056527097 0.139101937 1.332363001 0.009481067 0.177481024 5.46E-05 4.262663784 0.573788106 EDVEVAES(ph)PLR ddPTM_HeLa_Curcumin_4h_R1 1 EDVEVAESPLR 11 0 Q99567;J3KMX1 Q99567 NUP88 Nuclear pore complex protein Nup88 1 0 EDVEVAES(1)PLR 187.78 5.62E-05 196710000 4382.8 3623.3 3729 3724 4598.7 6530 4898.5 3573.8 3414.9 3070.8 TRUE FALSE FALSE 4035.896755 3936.481907 3867.20002 3708.591075 4543.863506 5175.604392 5035.938726 4663.435168 3040.294014 3177.510071 1.270144442 1.238857413 1.217053584 1.167137473 1.430007586 1.628823914 1.584869477 1.467638202 0.956816484 1 11.63368098 -1 0.104174442 0.815568763 3.156935887 0.788925325 0.099714876 42.49455317 0.313420398 0.775852641 14.31271208 0.1 1 2.341367124 EDVEVAES(ph)PLRVLAETPDSFEK ddPTM_HeLa_Curcumin_4h_R1 1 EDVEVAESPLRVLAETPDSFEK 22 1 Q99567;J3KMX1 Q99567 NUP88 Nuclear pore complex protein Nup88 1 0 EDVEVAES(0.992)PLRVLAET(0.007)PDS(0.002)FEK 70.453 0.0010367 10433000 1313.4 960.11 864.52 993.71 943.52 1457.8 1186.5 811.66 1228 1084.5 TRUE FALSE FALSE 1209.443004 1043.09763 896.5598717 989.5982913 932.2691402 1155.435847 1219.789997 1059.131398 1093.291472 1122.186294 1.077755993 0.929522697 0.798940315 0.881848492 0.830761474 1.029629263 1.086976381 0.943810669 0.974251314 1 10.13209648 -7.245950183 23.1226078 1.036718105 0.92817782 0.177584985 0.084278519 328.8483761 490911.4498 0.015230929 0.018606633 5.68E-08 7.245950183 -0.108540285 EDVSNFDDEFTSEAPILT(ph)PPREPR ddPTM_HeLa_Curcumin_4h_R1 2 EDVSNFDDEFTSEAPILTPPREPR 24 1 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 0 EDVSNFDDEFTSEAPILT(1)PPREPR;EDVSNFDDEFTSEAPILT(1)PPREPR ; 153.76 1.24E-07 48184000 3376.1 2452.3 2834.5 2771.8 3124.3 3833.4 2525.94 2445.4 3319.1 2532.81 TRUE FALSE FALSE 3108.878123 2664.265885 2939.549063 2760.331026 3087.044763 3038.309629 2596.811078 3190.991203 2955.003034 2620.824959 1.186221198 1.016575287 1.12161213 1.05322983 1.177890478 1.159295137 0.990837282 1.217552203 1.127508735 1 11.35580529 -9.572904345 1.342176777 0.99976972 1.119705591 0 0.080919172 0.448659895 1.444394877 0.04874445 0.011320926 2.67E-10 9.572904345 0.11993587 EDVTKDADLS(ph)PVNASIIK ddPTM_HeLa_Curcumin_4h_R1 2 EDVTKDADLSPVNASIIK 18 1 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 0 EDVT(0.012)KDADLS(0.986)PVNAS(0.001)IIK;EDVTKDADLS(1)PVNASIIK ; 122.34 0.00013685 54418000 10784 9498.9 9891.4 10741.4 11290.6 12602.3 8807.9 10752 10367.7 8909.1 TRUE FALSE FALSE 9930.435021 10319.94259 10257.98399 10696.95493 11155.96697 9988.440923 9055.025969 14030.2353 9230.389249 9218.690562 1.077206676 1.119458617 1.112737641 1.160355135 1.210146592 1.083498883 0.982246438 1.521933642 1.001269018 1 13.17034613 -4.254777598 24.93801931 1.068020782 1.521933855 0.773680144 0.070805832 285.7093503 1069508.556 0.011037342 0.142210205 5.56E-05 4.254777598 0.453913073 EEAATGGGS(ph)TGEADGK ddPTM_HeLa_Curcumin_4h_R1 1 EEAATGGGSTGEADGK 16 0 O43242 O43242 PSMD3 26S proteasome non-ATPase regulatory subunit 3 1 0 EEAAT(0.031)GGGS(0.919)T(0.049)GEADGK 196.45 1.37E-31 0 1455 1415.4 1467.8 1484 1846.5 1462.4 1151.1 1381 1184.7 1454.3 TRUE FALSE FALSE 1339.835215 1537.740869 1522.197959 1477.859601 1824.481693 1159.081755 1183.396768 1802.060543 1054.741374 1504.836817 0.890352495 1.021865529 1.011536894 0.982072996 1.212411654 0.770237505 0.786395412 1.197512264 0.70090083 1 10.55539134 -2.390999825 15.09407082 0.964952757 1.478132593 0 0.163504055 0 0 0.017531408 0 0.004064435 2.390999825 0.513179836 EEAENTLQS(ph)FRQDVDNASLAR ddPTM_HeLa_Curcumin_4h_R1 2 EEAENTLQSFRQDVDNASLAR 21 1 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 1 0 EEAENT(0.03)LQS(0.97)FRQDVDNASLAR;EEAENT(0.042)LQS(0.956)FRQDVDNAS(0.002)LAR ; 85.177 0.00036378 33405000 2243.39 1698.55 1884.77 2039.12 2060.92 2358.12 1872.66 1742.2 2044.53 1732.2 TRUE FALSE FALSE 2065.823314 1845.365093 1954.621234 2030.682662 2036.344875 1869.019331 1925.2018 2273.38876 1820.250174 1792.393821 1.152549897 1.029553367 1.0905088 1.132944467 1.13610349 1.042750376 1.074095312 1.268353379 1.015541424 1 10.80767194 -9.457371512 1.041773419 0.996023363 1.11372856 0.313748033 0.063790287 0.55440858 1.015477442 0.050749403 0.010951936 3.49E-10 9.457371512 0.117705197 EEAENTLQSFR ddPTM_HeLa_Curcumin_4h_R1 4 EEAENTLQSFR 11 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 0 ;;; ;;; 187.16 3.03E-12 314268000 11190.2 9916.4 10783.3 10560.1 11833.4 12926.3 11231.2 10726.5 11059.2 9910.5 FALSE FALSE TRUE 10304.48386 10773.52943 11182.93858 10516.4051 11692.29443 10245.23967 11546.31724 13996.96047 9846.033429 10254.88914 1.004836203 1.050574929 1.090498243 1.025501589 1.140167805 0.999059037 1.125932917 1.364906074 0.960130655 1 13.32402427 -1.000000001 0.819174319 1.017324279 99.75273732 0.791766782 0.050746605 162.2082678 0.488881347 0.007729473 29791.62959 0.1 1.000000001 98.73541305 EEAENTLQSFRQDVDNAS(ph)LAR ddPTM_HeLa_Curcumin_4h_R1 2 EEAENTLQSFRQDVDNASLAR 21 1 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 1 0 EEAENTLQS(0.001)FRQDVDNAS(0.999)LAR;EEAENTLQS(0.002)FRQDVDNAS(0.998)LAR ; 63.906 0.0030363 16784700 2029.2 1488.75 1637.17 1696.17 1334.01 2397.53 2019.75 1495.67 2388.12 2650.91 TRUE FALSE FALSE 1868.586679 1617.430916 1697.84496 1689.151698 1318.102802 1900.255252 2076.418749 1951.692898 2126.149211 2743.028925 0.681212896 0.589651426 0.61896721 0.61579799 0.480528218 0.692758007 0.75698026 0.711510141 0.775110022 1 11.42155412 -8.858461585 0.69565187 1.005474933 0.636475182 0.442050637 0.098198049 0.28217695 0.252916649 0.056327312 0.017941612 1.39E-09 8.858461585 -0.368999751 EEAENTLQSFRQDVDNASLAR ddPTM_HeLa_Curcumin_4h_R1 2 EEAENTLQSFRQDVDNASLAR 21 1 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 0 ; ; 159.18 1.04E-06 28376000 2013.68 1458.92 1366.89 1951.78 975.54 2066.78 1390.5 2045.7 2708.6 2080.23 FALSE FALSE TRUE 1854.295103 1585.022544 1417.548146 1943.704052 963.9073226 1638.106531 1429.513688 2669.424513 2411.473357 2152.517838 0.861454001 0.736357449 0.658553495 0.902990915 0.447804569 0.761018795 0.664112354 1.240140484 1.120303541 1 11.07180948 -7.967677474 0.968758282 0.97244089 0.757809744 0.211651637 0.199204511 0.566804971 1.132238847 0.051231126 0.041118809 1.08E-08 7.967677474 -0.214631147 EEAIEHNYGGHDDDLSVR ddPTM_HeLa_Curcumin_4h_R1 2 EEAIEHNYGGHDDDLSVR 18 0 F5H2X1;H3BND8;A0A669KBL1;Q93009-3;Q93009 F5H2X1 USP7 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 7 0 0 ; ; 120.99 0.00010019 13787600 3832 3341.1 3675.7 3724.2 4763.8 4972.2 4050.6 3459.2 3917.8 3457.4 FALSE FALSE TRUE 3528.693156 3629.889796 3811.924675 3708.790247 4706.994796 3940.909672 4164.248934 4513.894156 3488.027142 3577.544393 0.986345037 1.014631657 1.065514291 1.036686017 1.315705489 1.101568349 1.163996439 1.26172974 0.974978018 1 11.80475395 -5.903358221 6.906370716 1.002363762 1.199099385 0.736454829 0.057897943 0.082269472 5.07949024 0.008155616 0.0148632 1.25E-06 5.903358221 0.196735623 EEAKES(ph)PSAAGPEDK ddPTM_HeLa_Curcumin_4h_R1 2 EEAKESPSAAGPEDK 15 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 EEAKES(0.734)PS(0.266)AAGPEDK;EEAKES(0.967)PS(0.033)AAGPEDK ; 97.08 0.0021694 29092000 5412.2 4357.8 4856.4 4527.5 6282.6 7865.7 7083.5 2781.9 4687.8 3491.7 TRUE FALSE FALSE 4983.818659 4734.468814 5036.382456 4508.766405 6207.684098 6234.265155 7282.243946 3630.088504 4173.560068 3613.036315 1.379398994 1.310385062 1.393947366 1.24791616 1.718134986 1.725491972 2.015546845 1.004719628 1.155139253 1 11.81899604 -8.342525004 0.242796875 0.824500754 1.681977116 0.291791503 0.265273491 2.451052855 0.364891744 0.75162343 0.333145102 4.54E-09 8.342525004 0.857476362 EEAPAS(ph)PLRPLYPQISPLK ddPTM_HeLa_Curcumin_4h_R1 1 EEAPASPLRPLYPQISPLK 19 1 P85037;P85037-2;U3KQ26 P85037;U3KQ26 FOXK1 Forkhead box protein K1 1 0 EEAPAS(0.999)PLRPLY(0.001)PQISPLK 67.994 0.0050677 83620000 1748.5 1779.6 1930.2 1479.7 1863.1 2628 2113 1734.9 1552.5 1685.3 TRUE FALSE FALSE 1610.10438 1933.420694 2001.73491 1473.577393 1840.883749 2082.923176 2172.285093 2263.863024 1382.194634 1743.86405 0.923296963 1.10869921 1.147873259 0.845007037 1.055634899 1.194429793 1.245673419 1.298187794 0.792604581 1 10.76807186 -5.22273567 2.348635257 0.982052655 1.267388458 0.595090889 0.102483599 0.140105826 1.495327647 0.01271404 0.038317756 5.99E-06 5.22273567 0.285335803 EEAQLPFPTPSSYGADS(ph)S(ph)NQTY(ph)AHK ddPTM_HeLa_Curcumin_4h_R1 1 EEAQLPFPTPSSYGADSSNQTYAHK 25 0 Q00532-2 Q00532-2 3 0 EEAQLPFPT(0.025)PS(0.024)S(0.024)Y(0.12)GADS(0.804)S(0.665)NQT(0.656)Y(0.682)AHK 42.828 0.0077927 0 385.39 192 318.88 376.19 305.27 436.81 486.61 372.95 510.06 275.71 TRUE FALSE FALSE 354.8859748 208.5956245 330.6979733 374.6334255 301.6298546 346.2106821 500.262967 486.6607381 454.1076941 285.290902 1.243944242 0.731168162 1.159160601 1.31316289 1.057271201 1.213535657 1.753518824 1.705840371 1.591735632 1 8.156289929 -4.817255086 4.191825181 1.104559273 1.737923975 0.517721628 0.214417989 0.07865658 2.781621255 0.022177353 0.07643588 1.52E-05 4.817255086 0.633364702 EEAS(ph)DDDMEGDEAVVR ddPTM_HeLa_Curcumin_4h_R1 5 EEASDDDMEGDEAVVR 16 0 O75643;A0A494C1A5;O75643-2 O75643 SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 1 0 EEAS(1)DDDMEGDEAVVR;EEAS(1)DDDMEGDEAVVR;EEAS(1)DDDMEGDEAVVR;EEAS(1)DDDMEGDEAVVR;EEAS(1)DDDMEGDEAVVR ;;;; 279.19 2.29E-65 190994700 22675.2 8066.28 12704.4 14292.6 22081.2 19881.6 12915.8 15796 14021.4 6964.06 TRUE FALSE FALSE 20880.43399 8763.493301 13175.23624 14233.46101 21817.89611 15757.93205 13278.18259 20612.12768 12483.2875 7206.060567 2.897621218 1.216128177 1.828354913 1.975206963 3.027714784 2.186760977 1.842640991 2.860387794 1.732331748 1 12.81499506 -5.976954668 24.75711099 1.85457213 2.42405254 0.265820425 0.564856521 375.983385 403908.5635 0.113826169 0.206318613 1.05E-06 5.976954668 0.56948041 EEAS(ph)SPLK ddPTM_HeLa_Curcumin_4h_R1 1 EEASSPLK 8 0 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 0 EEAS(0.5)S(0.5)PLK 99.013 0.01563 27443000 6715.5 6655.2 7842.7 6970.4 9018.1 7752.3 6753 3652.5 5365.6 5879.6 TRUE FALSE FALSE 6183.961089 7230.445833 8133.357361 6941.558332 8910.565047 6144.385594 6942.471005 4766.130436 4777.007104 6083.915662 1.016444249 1.188452673 1.33686228 1.140968862 1.464610218 1.009939311 1.141118876 0.783398505 0.78518628 1 12.57078444 -7.270660162 19.52455152 1.007765215 1.164982756 0.195236686 0.184482573 46.13777595 97693.91481 0.028112573 0.032498937 5.36E-08 7.270660162 0.15721754 EEASDYLELDTIK ddPTM_HeLa_Curcumin_4h_R1 1 EEASDYLELDTIK 13 0 P14625;Q96GW1;A0A1W2PRR1 P14625 HSP90B1 Endoplasmin 0 0 229.68 1.55E-18 5662400 2000.8 1378.8 1823.1 1873.2 1963.3 1961 1616.4 1149.2 1579.7 1263.9 FALSE FALSE TRUE 1842.434569 1497.977328 1890.66569 1865.449195 1939.88893 1554.266495 1661.751834 1499.58579 1406.410862 1307.820431 1.408782525 1.145399852 1.445661534 1.426380221 1.483299147 1.188440292 1.270626911 1.146629732 1.075385297 1 10.35294875 -9.386666619 0.973763957 0.988915976 1.324203616 0.449547567 0.121241691 0.40199493 0.644781375 0.098914869 0.022220324 4.11E-10 9.386666619 0.33528764 EEASGSSVTAEEAK ddPTM_HeLa_Curcumin_4h_R1 2 EEASGSSVTAEEAK 14 0 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 0 ; ; 290.18 2.61E-112 4231500 1101.42 1020.86 1319.09 1007.6 1081.24 1360.85 1151.95 905.78 1089.74 922.59 FALSE FALSE TRUE 1014.241445 1109.09859 1367.976636 1003.430818 1068.346919 1078.59437 1184.270617 1181.948152 970.1982484 954.6499338 1.06242237 1.161785645 1.432961536 1.051098191 1.119098092 1.129832342 1.240528674 1.238095882 1.016286928 1 9.89882799 -7.307001613 3.19275202 1.026817554 1.196958118 0.402949804 0.096238054 0.193352399 3.864953881 0.017108588 0.019877836 4.93E-08 7.307001613 0.170140564 EEASGSSVTAEEAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EEASGSSVTAEEAKK 15 1 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 1 ; EEASGSSVTAEEAK(1)K;EEASGSSVTAEEAK(1)K 267.37 4.58E-77 18037100 2841.4 2610 2645.2 2427.2 4076.1 4734.6 4431.4 3660.1 3921.9 2598.3 FALSE TRUE FALSE 2616.500192 2835.59677 2743.233439 2417.15689 4027.49517 3752.59059 4555.733157 4776.047641 3491.677382 2688.590732 0.973186495 1.05467773 1.020323922 0.899042335 1.497994887 1.395746309 1.694468817 1.776413042 1.298701711 1 11.39263444 -5.324062472 1.107885955 0.985699432 1.763673605 0.768569001 0.145261285 0.120784205 0.260945439 0.015365711 0.06966089 4.74E-06 5.324062472 0.777974173 EEASGSSVTAEEAKK ddPTM_HeLa_Curcumin_4h_R1 2 EEASGSSVTAEEAKK 15 1 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 0 ; ; 173.33 2.11E-05 18145700 4936.9 4392.6 5217.6 4602 5113.8 6149.1 5001.4 4732.6 4695.1 4426.4 FALSE FALSE TRUE 4546.139156 4772.276771 5410.968846 4582.958143 5052.821275 4873.707345 5141.725823 6175.547954 4180.059277 4580.217071 0.99255976 1.041932445 1.181378254 1.000598459 1.1031838 1.064077809 1.122594354 1.348309012 0.912633443 1 12.16120026 -1 0.490267847 1.007920187 10.17243993 0.673404158 0.066296404 36.20100492 0.356246984 0.011926332 342.2375701 0.1 1 9.16451974 EEATYGVWAERDS(ph)DDERPSFGGK ddPTM_HeLa_Curcumin_4h_R1 2 EEATYGVWAERDSDDERPSFGGK 23 2 Q9UBB9;F6XM96;F6UKU9;F6SQZ1 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 1 0 EEATYGVWAERDS(1)DDERPSFGGK;EEATYGVWAERDS(0.98)DDERPS(0.02)FGGK ; 98.804 2.29E-05 128050000 9223.1 7717.2 8177.7 8249.7 7685.1 9433.9 7755.1 6393.5 8359.4 7243.2 TRUE FALSE FALSE 8493.081903 8384.240381 8480.772756 8215.564927 7593.460202 7477.202798 7972.687234 8342.848718 7442.394734 7494.900661 1.133181384 1.118659307 1.131539048 1.096153945 1.013150213 0.997638679 1.06374822 1.113136664 0.992994447 1 12.87169364 -4.258777627 22.63978997 1.066951238 1.113136722 0.066658907 0.054539578 192.6858564 1638504.474 0.008771417 0.078894644 5.51E-05 4.258777627 0.046185484 EEDEENDNDNES(ph)DHDEADS ddPTM_HeLa_Curcumin_4h_R1 2 EEDEENDNDNESDHDEADS 19 0 H0YBP8;Q9NRG0 H0YBP8 CHRAC1 Chromatin accessibility complex protein 1 1 0 EEDEENDNDNES(0.929)DHDEADS(0.071);EEDEENDNDNES(1)DHDEADS ; 128.01 6.45E-05 39843100 3414 3094.8 3479 3239.4 3623.6 4099.9 2861.1 3814.9 3205 3119.7 TRUE FALSE FALSE 3143.778298 3362.300722 3607.9348 3225.996221 3580.390937 3249.534525 2941.374766 4978.045448 2853.419519 3228.109343 0.973876026 1.041569651 1.117661893 0.9993454 1.109129387 1.006637068 0.911175692 1.542093194 0.883929017 1 11.65647373 -4.255227367 24.99864847 1.006011151 1.542093432 0.840294949 0.070267434 171.9824072 692079.9103 0.008313574 0.103186639 5.56E-05 4.255227367 0.536082281 EEDEEPES(ph)PPEK ddPTM_HeLa_Curcumin_4h_R1 2 EEDEEPESPPEK 12 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 EEDEEPES(1)PPEK;EEDEEPES(1)PPEK ; 249.28 6.96E-80 0 5201.7 4524 5138.7 4607.9 5955.3 5815.6 5199.5 5332.8 4136.9 4264.6 TRUE FALSE FALSE 4789.979956 4915.034401 5329.144742 4588.833731 5884.286937 4609.379005 5345.383976 6958.746171 3683.09242 4412.794533 1.08547541 1.11381447 1.207657575 1.039892906 1.33346044 1.044548748 1.211337609 1.576947696 0.834639454 1 12.10747686 -1 0.54480226 1.057869759 21.02742709 0.595201989 0.122947774 52.65764056 0.446740714 0.01863439 1233.573897 0.1 1 19.96955733 EEDEEPES(ph)PPEKK ddPTM_HeLa_Curcumin_4h_R1 4 EEDEEPESPPEKK 13 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK;EEDEEPES(1)PPEKK ;;; 164.93 0.00027826 2489205000 16804.6 15991.8 17855.6 15607.2 19531.8 17949.8 16414.9 16726.3 15052.6 14315.2 TRUE FALSE FALSE 15474.49818 17374.05993 18517.34424 15542.62154 19298.89604 14226.80914 16875.45792 21826.07187 13401.36744 14812.65213 1.044681131 1.17292027 1.250103228 1.049280129 1.302865676 0.960449825 1.139259719 1.473474951 0.904724375 1 13.85454235 -1 0.154693148 0.962505072 2.181498951 0.387331745 0.129659888 56.07736059 0.555154179 0.245160097 15.51910074 0.1 1 1.218993879 EEDEHPY(ph)ELLLTAETK ddPTM_HeLa_Curcumin_4h_R1 1 EEDEHPYELLLTAETK 16 0 A0A3B3ISP1;Q92625 A0A3B3ISP1 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 0 EEDEHPY(1)ELLLTAETK 149.3 0.0016589 1911100 1687.2 1660.4 1533.1 1712.5 1805.3 2840.5 1945.7 796.32 2018.2 1430.4 TRUE FALSE FALSE 1553.65634 1803.917577 1589.918035 1705.414129 1783.772977 2251.348281 2000.291105 1039.114302 1796.808509 1480.106294 1.049692408 1.218775696 1.074191794 1.152224091 1.205165456 1.521072028 1.351450983 0.702053837 1.213972616 1 10.53148507 -7.181823831 0.835627798 1.010901111 1.211364475 0 0.209106869 0.776687169 1.093905889 0.045930959 0.057312602 6.58E-08 7.181823831 0.200463365 EEDEPEERS(ph)GDETPGS(ph)EVPGDK ddPTM_HeLa_Curcumin_4h_R1 1 EEDEPEERSGDETPGSEVPGDK 22 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 2 0 EEDEPEERS(0.848)GDET(0.479)PGS(0.673)EVPGDK 56.332 0.010083 27452000 3442.1 2890.4 2641 2371.5 3182.6 3035.9 2459.6 3226 2498.9 2283 TRUE FALSE FALSE 3169.654153 3140.233297 2738.877783 2361.687361 3144.649574 2406.220118 2528.609756 4209.592549 2224.776922 2362.33408 1.341746783 1.329292636 1.159394772 0.999726237 1.331162091 1.018577406 1.070386182 1.781963265 0.941770658 1 11.20599729 -9.464273482 1.201937629 1.000032722 1.244279998 0.20958301 0.216093278 0.708725253 1.83217044 0.142484469 0.035198471 3.43E-10 9.464273482 0.244247276 EEDEPEERS(ph)GDETPGSEVPGDK ddPTM_HeLa_Curcumin_4h_R1 4 EEDEPEERSGDETPGSEVPGDK 22 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 0 EEDEPEERS(0.811)GDET(0.15)PGS(0.039)EVPGDK;EEDEPEERS(0.999)GDET(0.001)PGSEVPGDK;EEDEPEERS(0.88)GDET(0.083)PGS(0.037)EVPGDK;EEDEPEERS(0.988)GDET(0.005)PGS(0.007)EVPGDK ;;; 111.27 9.82E-06 1129321000 17401.5 14764.5 17506 15157.5 19272 17738.9 16912 15040.6 13494.1 13165.2 TRUE FALSE FALSE 16024.15291 16040.67759 18154.78776 15094.78228 19042.19399 14059.65218 17386.5052 19626.4097 12013.83099 13622.68972 1.17628407 1.177497096 1.33268746 1.108061814 1.397829238 1.032076078 1.276290187 1.440714727 0.8818986 1 13.73372396 -13.52287874 0.095328524 0.154983804 1.438705904 0.519358205 0.119336125 86.44862204 0.619406088 14.56377654 1.087551839 3.00E-14 13.52287874 1.2837221 EEDEPEERS(ph)GDETPGSEVPGDKAAEEQGDDQDSEK ddPTM_HeLa_Curcumin_4h_R1 2 EEDEPEERSGDETPGSEVPGDKAAEEQGDDQDSEK 35 2 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 0 EEDEPEERS(0.996)GDET(0.004)PGSEVPGDKAAEEQGDDQDSEK;EEDEPEERS(0.965)GDET(0.027)PGS(0.008)EVPGDKAAEEQGDDQDSEK ; 82.942 2.08E-08 211561000 3125.89 2491.69 2257.21 2015.97 2387.89 2512.89 1978.12 2142.8 2580.15 2352.63 TRUE FALSE FALSE 2878.472508 2707.060581 2340.864188 2007.62845 2359.415971 1991.688288 2033.620723 2796.129856 2297.114 2434.383717 1.182423497 1.112010634 0.9615839 0.824696795 0.969204631 0.81814887 0.835373942 1.148598652 0.943612128 1 11.24934087 -6.643667813 4.511542836 1.090304215 0.910219734 0.246700366 0.10986651 0.171441127 6.023532074 0.017194067 0.024496997 2.27E-07 6.643667813 -0.180084481 EEDGADAS(ph)EEDLTR ddPTM_HeLa_Curcumin_4h_R1 2 EEDGADASEEDLTR 14 0 Q86X53;E5RHA3 Q86X53 ERICH1 Glutamate-rich protein 1 1 0 EEDGADAS(1)EEDLTR;EEDGADAS(0.999)EEDLT(0.001)R ; 260.73 2.08E-39 65327000 5006 3700.7 4912.9 4825.2 5456.4 5521.4 4595.7 2802.1 4526 3353.1 TRUE FALSE FALSE 4609.769818 4020.572018 5094.976396 4805.234601 5391.335994 4376.199401 4724.642973 3656.447391 4029.509123 3469.619975 1.32860943 1.158793195 1.46845373 1.384945508 1.553869309 1.261290698 1.361717712 1.053846651 1.161369012 1 11.76056194 -9.144924139 0.601479124 0.960922887 1.339190741 0.284350336 0.143759307 0.750866043 0.420089834 0.153863576 0.030982255 7.16E-10 9.144924139 0.378267854 EEEEEEEEDQEGDRETTIR ddPTM_HeLa_Curcumin_4h_R1 1 EEEEEEEEDQEGDRETTIR 19 1 A0A0B4J2E5;Q15269 A0A0B4J2E5 PWP2 Periodic tryptophan protein 2 homolog 0 0 199.33 8.20E-11 4198700 692.34 847.95 731.52 653.15 1001.7 750.4 773.5 447.31 581.21 570.91 FALSE FALSE TRUE 637.5405584 921.2430196 758.6307747 650.4474384 989.7553817 594.7585812 795.2023282 583.6927598 517.4527171 590.74908 1.079207027 1.559448928 1.284184437 1.101055356 1.67542433 1.006787148 1.346091522 0.988055301 0.875926404 1 9.206401667 -7.488686096 19.41133906 1.03494244 1.283405438 0.279379375 0.213849709 31.15142507 17685.91868 0.033150758 0.036752583 3.25E-08 7.488686096 0.248462998 EEEEGISQES(ph)S(ph)EEEQ ddPTM_HeLa_Curcumin_4h_R1 2 EEEEGISQESSEEEQ 15 0 P17096;P17096-2 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 2 0 EEEEGISQES(1)S(1)EEEQ;EEEEGISQES(1)S(1)EEEQ ; 111.06 0.0050562 34966000 10499.2 9741.1 10214.4 9042.3 11699 11987.8 9679.1 10859.8 9111.5 8417.3 TRUE FALSE FALSE 9668.177241 10583.07728 10592.95465 9004.885358 11559.49707 9501.39515 9950.669496 14170.90303 8111.991246 8709.800548 1.110034287 1.21507688 1.216210933 1.033879629 1.327182753 1.090885503 1.142468124 1.627006606 0.931363606 1 13.08842397 -1.893364049 1.219332725 1.091853052 199.9998295 0.6399633 0.112689903 255.4008416 1.313025397 0.016397031 141041.4675 0.012783093 1.893364049 198.9079765 RHS(ph)VTLPSSK ddPTM_HeLa_Curcumin_4h_R1 1 RHSVTLPSSK 10 1 G3V2D5;G3V515;G3V2P5;Q07352 G3V2D5 ZFP36L1 "Zinc finger protein 36, C3H1 type-like 1" 1 0 RHS(0.943)VT(0.057)LPSSK 78.985 0.015484 51070000 3126 2350.4 2756.4 3123.7 3092.8 7138.7 6789.9 8233.4 3690.5 2626.9 TRUE FALSE FALSE 2878.573801 2553.558103 2858.554609 3110.774957 3055.92038 5658.05315 6980.40632 10743.72576 3285.661383 2718.184579 1.059006008 0.939435137 1.051641095 1.144431096 1.124250503 2.081555901 2.56803985 3.952537234 1.208770518 1 11.40842771 -4.273190046 0.88194269 1.012245956 5.556850769 0.979988628 0.131782707 0.159244715 0.091944804 0.016940619 0.694936823 5.33E-05 4.273190046 4.544604814 up EEEEQQEGGFAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 EEEEQQEGGFASPR 14 0 A0A087WVR3;A0A087WTW0;Q96T88;Q96T88-2;A0A087WWG9 A0A087WVR3 UHRF1 E3 ubiquitin-protein ligase UHRF1 1 0 EEEEQQEGGFAS(1)PR 153.24 0.00043761 1989600 601.04 449.76 546.8 447.2 568.01 682.8 556.12 389.14 550.95 659.79 TRUE FALSE FALSE 553.4670498 488.6352503 567.064889 445.3496049 561.2368517 541.1795833 571.7232305 507.7869946 490.5121634 682.7176534 0.810682201 0.715720837 0.830599423 0.652318865 0.822062897 0.792684326 0.837422656 0.743773055 0.718470016 1 9.415145247 -8.773968769 0.67338833 1.002606505 0.772506255 0 0.10174798 0.301044389 0.259046574 0.0362638 0.012311481 1.68E-09 8.773968769 -0.23010025 EEEEVGFDWSDR ddPTM_HeLa_Curcumin_4h_R1 1 EEEEVGFDWSDR 12 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 153.1 0.0034225 2642900 1093.6 845.76 834.6 1118.2 1229 1102.8 953.6 1046.5 1086.9 1038.3 FALSE FALSE TRUE 1007.040406 918.8637258 865.5310102 1113.573185 1214.344978 874.0668489 980.3554495 1365.573033 967.6697893 1074.380848 0.937321629 0.85524954 0.805609121 1.036478998 1.130274223 0.813554012 0.912484108 1.271032554 0.900676693 1 10.06928978 EEELREYQER ddPTM_HeLa_Curcumin_4h_R1 1 EEELREYQER 10 1 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 99.788 0.010967 10074000 3006.2 2572.9 2771.5 3279.5 2307.7 3533.3 2241.9 2432.9 3456.8 2860.7 FALSE FALSE TRUE 2768.256098 2795.290011 2874.214228 3265.930298 2280.182185 2800.453752 2304.80168 3174.68001 3077.597688 2960.109112 0.935187182 0.944319924 0.970982528 1.10331416 0.770303424 0.946064366 0.778620515 1.072487496 1.039690624 1 11.53143464 -5.757097158 24.99999842 0.975094196 0.887650913 0.216349001 0.093287025 138.7472343 798815.3692 0.012106449 0.02355479 1.75E-06 5.757097158 -0.087443283 EEEMQPAEEGPS(ph)VPK ddPTM_HeLa_Curcumin_4h_R1 2 EEEMQPAEEGPSVPK 15 0 Q6ZU67-5;Q6ZU67-4;Q6ZU67-2;Q6ZU67 Q6ZU67-5 BEND4 BEN domain-containing protein 4 1 0 EEEMQPAEEGPS(1)VPK;EEEMQPAEEGPS(1)VPK ; 90.412 0.008565 73690300 3471.7 3040.7 3221.1 3377.6 3106.3 3723 3547.9 2177.16 3355.4 3427.2 TRUE FALSE FALSE 3196.911282 3303.524559 3340.4768 3363.624386 3069.259401 2950.807833 3647.444525 2840.966062 2987.321015 3546.294945 0.901479243 0.931542528 0.941962485 0.948489744 0.865483399 0.832081899 1.028522608 0.801108229 0.842378048 1 11.79209681 -13.52287874 0.214370225 1.476233587 0.893067252 0 0.078035568 48.28333281 0.605089574 9.629370633 0.048292146 3.00E-14 13.52287874 -0.583166335 EEENADS(ph)DDEGELQDLLSQDWR ddPTM_HeLa_Curcumin_4h_R1 2 EEENADSDDEGELQDLLSQDWR 22 0 J3QQQ3;Q96NB3 J3QQQ3 ZNF830 Zinc finger protein 830 1 0 EEENADS(1)DDEGELQDLLSQDWR;EEENADS(1)DDEGELQDLLSQDWR ; 181.49 2.00E-10 4499600 2018.9 1874.42 1815.51 1781.53 2082.93 2519.7 1833.16 1888.72 2109.29 2155 TRUE FALSE FALSE 1859.101935 2036.436513 1882.794398 1774.158501 2058.09242 1997.085817 1884.593536 2464.582033 1877.906164 2229.88609 0.833720585 0.913246879 0.84434555 0.795627413 0.922958545 0.895599926 0.84515238 1.105250194 0.842153405 1 11.1227543 -4.251576024 24.40642028 0.900492349 1.10525035 0.540305351 0.059721564 777.9862753 1925036.201 0.010338336 0.180980024 5.60E-05 4.251576024 0.204758001 EEENS(ph)EEELAAATTSK ddPTM_HeLa_Curcumin_4h_R1 2 EEENSEEELAAATTSK 16 0 P10244-2;P10244 P10244-2 MYBL2 Myb-related protein B 1 0 EEENS(1)EEELAAATTSK;EEENS(1)EEELAAATTSK ; 159.95 6.75E-11 0 2037.72 1719.82 1739.81 1735.26 2156.86 1785.59 1698.73 1228.08 1702.83 1623.29 TRUE FALSE FALSE 1876.432312 1868.473577 1804.288889 1728.079954 2131.140853 1415.238506 1746.391792 1602.515939 1516.033809 1679.699207 1.117124009 1.112385819 1.074173806 1.028803221 1.268763386 0.842554727 1.039705076 0.954049351 0.902562675 1 10.71398719 -5.23047575 24.99950726 1.072614922 0.954863299 0.254003202 0.098975575 683.109617 551530.3102 0.011876829 0.03027719 5.88E-06 5.23047575 -0.117751622 EEEQEDLTKDMDEPS(ph)PVPNVEEVTLPK ddPTM_HeLa_Curcumin_4h_R1 2 EEEQEDLTKDMDEPSPVPNVEEVTLPK 27 1 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 0 EEEQEDLTKDMDEPS(1)PVPNVEEVTLPK;EEEQEDLTKDMDEPS(1)PVPNVEEVTLPK ; 123.54 9.31E-08 16516000 9811.8 8028.9 9177 8605.2 9599.3 10793.5 8533.4 8514.9 8949.3 7613.5 TRUE FALSE FALSE 9035.185677 8722.88234 9517.107693 8569.593962 9484.834617 8554.806432 8772.824238 11111.05381 7967.58418 7878.068558 1.146878275 1.107236155 1.208050885 1.087778546 1.203954313 1.085901496 1.113575513 1.410377903 1.011362636 1 12.94362626 -13.52287875 0.031024685 4.65E-13 1.839542095 0.461036308 0.08220539 779.6670476 1.941350616 88.66908694 36.97503963 3.00E-14 13.52287875 1.839542095 EEET(ph)KTSNGDLSDSTVSADPVVK ddPTM_HeLa_Curcumin_4h_R1 1 EEETKTSNGDLSDSTVSADPVVK 23 1 A0A087X256;Q2M389 A0A087X256 KIAA1033 WASH complex subunit 7 1 0 EEET(0.329)KT(0.329)S(0.329)NGDLS(0.01)DS(0.001)T(0.001)VS(0.001)ADPVVK 59.163 0.0070715 7539700 1062.1 570.37 978.51 875.54 952.63 1132 627.27 824.64 1179.6 806.73 TRUE FALSE FALSE 978.0336643 619.6702413 1014.774441 871.9172475 941.2705094 897.2104397 644.869508 1076.06894 1050.200831 834.7638075 1.171629215 0.742330029 1.215642595 1.044507727 1.127589027 1.074807546 0.77251733 1.28906995 1.258081414 1 9.705224241 EEEWDPEYT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 EEEWDPEYTPK 11 0 Q9Y2W1;A0A3B3ITZ9;Q9NYF8-2;Q9NYF8;Q9NYF8-4;H0YF14 Q9Y2W1;Q9NYF8-2 THRAP3;BCLAF1 Thyroid hormone receptor-associated protein 3;Bcl-2-associated transcription factor 1 1 0 EEEWDPEY(0.002)T(0.998)PK;EEEWDPEYT(1)PK;EEEWDPEYT(1)PK ;; 193.49 8.15E-05 173365000 17511.4 14650.7 15804.5 14893.6 18987.7 28163 30505.5 10688 15772 13457.5 TRUE FALSE FALSE 16125.35421 15917.04123 16390.22867 14831.97423 18761.28408 22321.67634 31361.40223 13946.722 14041.85106 13925.14712 1.15800243 1.143042948 1.177023735 1.065121546 1.347295214 1.602975979 2.252141536 1.001549346 1.008380805 1 13.76540495 -5.450716301 2.594669102 1.090257382 1.684366201 0.399271301 0.287280491 0.17798465 2.339987145 0.037969181 0.093820294 3.54E-06 5.450716301 0.59410882 EEFASTCPDDEEIELAYEQVAK ddPTM_HeLa_Curcumin_4h_R1 1 EEFASTCPDDEEIELAYEQVAK 22 0 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 0 0 192.6 3.73E-13 8291500 3834.4 3015.4 3456.6 3683.6 3655.8 4189 3317 3862.6 4198.9 3126.2 FALSE FALSE TRUE 3530.903194 3276.03774 3584.704637 3668.358239 3612.206973 3320.15418 3410.066093 5040.288959 3738.291175 3234.835217 1.091524902 1.012737132 1.108156798 1.134017034 1.116658726 1.026375057 1.054169954 1.558128504 1.155635735 1 11.65947651 -4.261264369 24.99999989 1.056695613 1.558128652 0.87429382 0.054126809 3.213320852 458644.8287 0.007282123 0.056365031 5.48E-05 4.261264369 0.501433038 LTSS(ph)LEAGLQR ddPTM_HeLa_Curcumin_4h_R1 2 LTSSLEAGLQR 11 0 B7Z879;A0A087WXL6;Q9H270 B7Z879 VPS11 Vacuolar protein sorting-associated protein 11 homolog 1 0 LTS(0.037)S(0.963)LEAGLQR;LTS(0.02)S(0.98)LEAGLQR ; 164.48 0.00027457 12092300 6421.3 5198.7 5715.3 6040 6183.6 5147.4 3193.5 1242.18 6805.3 6106.7 TRUE FALSE FALSE 5913.047329 5648.052463 5927.114046 6015.00808 6109.864609 4079.771217 3283.101015 1620.914964 6058.775616 6318.90737 0.935770535 0.893833717 0.937996666 0.951906355 0.966917894 0.645645042 0.519567834 0.256518235 0.958832795 1 12.6254594 -4.732115777 1.196919494 0.963387802 0.198324779 0.960825842 0.046830731 0.103023299 0.202441526 0.00746683 0.079157932 1.85E-05 4.732115777 -0.765063024 down EEFTAFLHPEEFEHMK ddPTM_HeLa_Curcumin_4h_R1 2 EEFTAFLHPEEFEHMK 16 0 Q15293;Q15293-2;E9PP27 Q15293 RCN1 Reticulocalbin-1 0 0 ; ; 103.14 0.00062548 27547000 11744.4 10286.5 11892.8 10784.4 12110 12889.9 9497.2 7166.7 11094.6 9839.4 FALSE FALSE TRUE 10814.81835 11175.61922 12333.55763 10739.77701 11965.59616 10216.38944 9763.665872 9351.793839 9877.550137 10181.31842 1.062221797 1.097659337 1.211391013 1.054851304 1.175250166 1.003444645 0.95897854 0.918524837 0.970164151 1 13.31363677 -4.865101128 3.352513191 1.060348925 0.935479234 0.37304203 0.071071004 0.2233321 4.86044637 0.010571838 0.038046645 1.36E-05 4.865101128 -0.124869691 EEGDLGPVYGFQWR ddPTM_HeLa_Curcumin_4h_R1 1 EEGDLGPVYGFQWR 14 0 P04818;P04818-2 P04818 TYMS Thymidylate synthase 0 0 295.79 1.55E-76 12105000 1217.1 931.08 731.71 806.65 840.18 1764.4 1264.2 1158 933.14 1106.3 FALSE FALSE TRUE 1120.765251 1011.558406 758.8278163 803.312296 830.1614022 1398.443551 1299.67005 1511.068869 830.7768766 1144.743843 0.979053312 0.883654813 0.662880016 0.701739783 0.725194031 1.221621379 1.135337008 1.320006112 0.725731684 1 10.16080909 -5.234258038 23.94583366 0.919070006 1.216623192 0.563032012 0.147158319 336.1607727 296145.0114 0.022907712 0.058382492 5.83E-06 5.234258038 0.297553186 EEGGEGT(ph)PVKQDLSAPPGYTLTENVAR ddPTM_HeLa_Curcumin_4h_R1 1 EEGGEGTPVKQDLSAPPGYTLTENVAR 27 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;Q9Y4B5-4 Q9Y4B5;Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 1 0 EEGGEGT(1)PVKQDLSAPPGYTLTENVAR 96.022 3.04E-06 14285000 2416.9 1986.1 2104.8 1911.9 2314.4 2658.5 2329.8 927.11 1984 1654 TRUE FALSE FALSE 2225.599815 2157.769634 2182.80574 1903.989064 2286.802292 2107.097133 2395.167918 1209.781571 1766.360164 1711.476377 1.300397624 1.26076507 1.275393438 1.112483403 1.336157672 1.231157591 1.399474717 0.706864312 1.032068095 1 10.74102566 -9.422164204 1.146078514 0.999788853 1.223416521 0.135110174 0.182686595 0.649940103 1.524586991 0.115264701 0.02893239 3.78E-10 9.422164204 0.223627668 EEGGEGTPVKQDLS(ph)APPGYTLTENVAR ddPTM_HeLa_Curcumin_4h_R1 1 EEGGEGTPVKQDLSAPPGYTLTENVAR 27 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;Q9Y4B5-4 Q9Y4B5;Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 1 0 EEGGEGT(0.029)PVKQDLS(0.967)APPGY(0.002)T(0.002)LT(0.001)ENVAR 95.742 1.68E-06 8743900 2020.4 1890.7 1983 2065.9 1846.7 2614.1 2187.4 795.4 2253.8 1796.1 TRUE FALSE FALSE 1860.483208 2054.123683 2056.491724 2057.351853 1824.679309 2071.906193 2248.772557 1037.913798 2006.563779 1858.514341 1.001059377 1.105250381 1.106524539 1.106987343 0.981794581 1.114818512 1.209983968 0.55846424 1.0796601 1 10.85993411 -4.248453145 24.99385287 1.038508701 0.558463931 0.801274218 0.075360606 806.8392832 1552850.66 0.01126872 0.283254452 5.64E-05 4.248453145 -0.480044769 EEGINKSEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 EEGINKSEKR 10 2 P09874 P09874 PARP1 Poly [ADP-ribose] polymerase 1 0 1 EEGINK(0.001)SEK(0.999)R 68.626 0.018775 20643000 6661.9 6470.9 6566 6585.5 5370.2 6433.4 5228.3 5837.1 5910 5872.2 FALSE TRUE FALSE 6134.603585 7030.215762 6809.341736 6558.250946 5306.163872 5099.040321 5374.992027 7616.804919 5261.687786 6076.258513 1.009602138 1.156997476 1.120647142 1.079323885 0.873261706 0.839174355 0.884589096 1.253535363 0.865942055 1 12.56896753 -5.773265473 24.99919108 1.031695594 0.94824606 0.070043489 0.130238797 406.5218769 859347.6343 0.017752517 0.032365633 1.69E-06 5.773265473 -0.083449533 EEGPAPCK(ac)QMK ddPTM_HeLa_Curcumin_4h_R1 2 EEGPAPCKQMK 11 1 D6RCB6;Q8IUF8-2;Q8IUF8-4;Q8IUF8 D6RCB6 MINA Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA 0 1 ; EEGPAPCK(1)QMK;EEGPAPCK(1)QMK 148.32 1.02E-05 4127000 2068.2 1613.27 2272.8 2140.84 2632.3 2706.7 2247.6 2376.4 1987.6 1803.73 FALSE TRUE FALSE 1904.499788 1752.71387 2357.031967 2131.981771 2600.911542 2145.299909 2310.661607 3100.95342 1769.565253 1866.409483 1.020408332 0.939083243 1.262869691 1.142290473 1.393537466 1.149426173 1.238025003 1.661453957 0.948112013 1 10.86604983 -1 0.281891085 0.986158782 5.308823918 0.693335773 0.118702444 19.67490466 0.250905745 0.048408998 42.55397149 0.1 1 4.322665136 EEGS(ph)DIEDEDMEELLNDTR ddPTM_HeLa_Curcumin_4h_R1 2 EEGSDIEDEDMEELLNDTR 19 0 F5H5U2;Q8NHQ9-2;Q8NHQ9 F5H5U2 DDX55 ATP-dependent RNA helicase DDX55 1 0 EEGS(1)DIEDEDMEELLNDTR;EEGS(1)DIEDEDMEELLNDTR ; 335.98 2.44E-154 46644000 2880.98 2146.77 2389.4 2201.28 2407.5 2686.29 2111.87 1508 2282.91 2186.71 TRUE FALSE FALSE 2652.947393 2332.327233 2477.953266 2192.171687 2378.792135 2129.123173 2171.123388 1967.782258 2032.480485 2262.69801 1.172470821 1.030772654 1.095132119 0.968830872 1.05130783 0.940966565 0.959528571 0.869661903 0.898255302 1 11.14382833 -5.101201046 0.745992895 1.079153935 0.868496102 0.201832623 0.077778886 0.788467728 0.580656061 0.012354328 0.109637597 7.92E-06 5.101201046 -0.210657833 EEGSLS(ph)DTEADAVSGQLPDPTTNPSAGK ddPTM_HeLa_Curcumin_4h_R1 2 EEGSLSDTEADAVSGQLPDPTTNPSAGK 28 0 Q8N1G4 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 1 0 EEGS(0.214)LS(0.776)DT(0.01)EADAVSGQLPDPTTNPSAGK;EEGS(0.06)LS(0.88)DT(0.06)EADAVSGQLPDPTTNPSAGK ; 148.9 1.20E-10 25675000 6243.2 5344.7 6061.4 5294 7948.3 6106.5 5816.2 5298.6 3935.4 4135.2 TRUE FALSE FALSE 5749.044132 5806.672052 6286.040816 5272.094831 7853.521714 4839.943066 5979.386918 6914.118748 3503.696466 4278.897892 1.343580585 1.35704852 1.469079416 1.23211513 1.835407601 1.131119084 1.397412855 1.615864394 0.81883152 1 12.06302354 -9.057315083 0.365073556 0.870144183 1.465777768 0.535149712 0.190452354 1.598860352 0.315042869 0.383244661 0.073366856 8.76E-10 9.057315083 0.595633585 EEHGGLIRS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 EEHGGLIRSPR 11 1 P26368;P26368-2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 1 0 EEHGGLIRS(1)PR;EEHGGLIRS(1)PR;EEHGGLIRS(1)PR ;; 75.102 0.014746 1048306000 11317.4 9577.1 10980 10851 11554 12067.1 9971.8 5277 9864.9 9272.9 TRUE FALSE FALSE 10421.61585 10404.90185 11386.92846 10806.10144 11416.2261 9564.247436 10251.58187 6885.933008 8782.745151 9595.132585 1.086135679 1.084393755 1.186740085 1.126206578 1.18979347 0.996781165 1.068414822 0.717648552 0.915333381 1 13.22808703 -4.261415596 23.41739065 1.068189115 0.717648554 0.632111005 0.081182772 0.368701432 357156.3039 0.010372407 0.079760657 5.48E-05 4.261415596 -0.350540561 EEHLCTQR ddPTM_HeLa_Curcumin_4h_R1 4 EEHLCTQR 8 0 A0A087WWU8;P06753-2;P06753-5;P06753-7;J3KN67 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 0 ;;; ;;; 137.14 0.0029279 25892600 11521.7 11470.8 12289.9 10780.7 12870.1 12852.5 10502.9 11931.1 11726.3 10776.7 FALSE FALSE TRUE 10609.74529 12462.28484 12745.37451 10736.09232 12716.63246 10186.74662 10797.58311 15568.83747 10439.95423 11151.18952 0.951445159 1.117574481 1.14296098 0.962775523 1.140383493 0.913512106 0.968289803 1.396159346 0.936218886 1 13.44490999 -4.258402296 24.78040143 1.002328474 1.396159509 0.650109761 0.083483391 114.8180436 936776.867 0.011387157 0.107069099 5.52E-05 4.258402296 0.393831035 EEILAQAK ddPTM_HeLa_Curcumin_4h_R1 2 EEILAQAK 8 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ; ; 148.38 0.00023639 11310600 6611.7 5119.7 5980.1 6125 6902.6 6937.1 5670 5875.6 6034.2 5563.4 FALSE FALSE TRUE 6088.376968 5562.224055 6201.727767 6099.656373 6820.291003 5498.267263 5829.08494 7667.043392 5372.263357 5756.727736 1.05761072 0.966212805 1.077300865 1.059570064 1.184751358 0.955102884 1.012569155 1.331840543 0.933214771 1 12.49103327 -4.258913586 24.92018224 1.034107537 1.331840653 0.631638264 0.069583025 99.29364899 979596.5295 0.008366676 0.076725847 5.51E-05 4.258913586 0.297733116 EEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKR ddPTM_HeLa_Curcumin_4h_R1 1 EEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKR 32 2 Q5TB25;Q9BTT0-3;Q9BTT0-2;Q9BTT0 Q5TB25 ANP32E Acidic leucine-rich nuclear phosphoprotein 32 family member E 0 0 117.96 7.70E-14 20308000 1647.3 931 1051.1 1188.2 1089.6 1867.6 1038.4 959.78 1379.9 1167.7 FALSE FALSE TRUE 1516.914467 1011.471492 1090.054691 1183.283543 1076.607232 1480.238708 1067.534709 1252.412504 1228.528422 1208.277488 1.255435512 0.837118544 0.902155921 0.9793144 0.891026476 1.225081757 0.883517834 1.036527218 1.016760168 1 10.2387361 -7.260351651 24.9999692 1.120622323 0.967127804 0.170009161 0.122033822 112.376987 2582837.576 0.022642518 0.026920877 5.49E-08 7.260351651 -0.153494519 EEIQETQT(ph)PTHSR ddPTM_HeLa_Curcumin_4h_R1 1 EEIQETQTPTHSR 13 0 H7BZL0;Q9BYG3 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 0 EEIQET(0.006)QT(0.99)PT(0.003)HSR 149.3 0.0016929 11855000 1261.2 1035.9 1174.3 1252.6 1327.5 1756.8 1411 818.55 1277.9 1023.8 TRUE FALSE FALSE 1161.374689 1125.43858 1217.820591 1247.417073 1311.67043 1392.419877 1450.588862 1068.122127 1137.717567 1059.376974 1.09628085 1.062358922 1.149563018 1.177500648 1.238152671 1.314376196 1.369284871 1.008254996 1.073949685 1 10.04900034 -6.622956584 0.778441627 1.034400409 1.250909386 0.405505793 0.092061712 0.376862258 0.458671123 0.019025893 0.034541059 2.38E-07 6.622956584 0.216508978 EEKDKDDQEWES(ph)PSPPKPTVFISGVIAR ddPTM_HeLa_Curcumin_4h_R1 1 EEKDKDDQEWESPSPPKPTVFISGVIAR 28 3 P51397 P51397 DAP Death-associated protein 1 1 0 EEKDKDDQEWES(0.804)PS(0.195)PPKPTVFISGVIAR 85.17 3.15E-06 259480000 2687.3 2478.4 3070.1 2908.6 2717.4 3015.8 2436.9 2396.8 2775.3 2529.3 TRUE FALSE FALSE 2474.597369 2692.621852 3183.880607 2896.564984 2684.99678 2390.289085 2505.272855 3127.573286 2470.856533 2617.192987 0.945515819 1.028820521 1.216524965 1.106744898 1.025907067 0.913302572 0.957236577 1.195010571 0.944086487 1 11.35380459 -7.008372866 24.83241832 0.974950134 1.062196513 0.21300953 0.089660895 517.2226533 1533993.726 0.015301123 0.019581968 9.81E-08 7.008372866 0.08724638 EEKDKDDQEWESPS(ph)PPKPTVFISGVIAR ddPTM_HeLa_Curcumin_4h_R1 1 EEKDKDDQEWESPSPPKPTVFISGVIAR 28 3 P51397 P51397 DAP Death-associated protein 1 1 0 EEKDKDDQEWES(0.086)PS(0.901)PPKPT(0.012)VFIS(0.001)GVIAR 65.387 0.00033033 272430000 2664.8 2333.3 2477.4 2475.5 3134.4 3063.3 2261.2 2391.8 2822.4 2485.4 TRUE FALSE FALSE 2453.878268 2534.980055 2569.214623 2465.257037 3097.024327 2427.937049 2324.643186 3121.04881 2512.789781 2571.767465 0.954160243 0.98569567 0.999007359 0.958584736 1.20423964 0.94407332 0.903908778 1.213581263 0.977067256 1 11.32854449 EEKREEDEENDNDNES(ph)DHDEADS ddPTM_HeLa_Curcumin_4h_R1 1 EEKREEDEENDNDNESDHDEADS 23 2 H0YBP8;Q9NRG0 H0YBP8 CHRAC1 Chromatin accessibility complex protein 1 1 0 EEKREEDEENDNDNES(0.946)DHDEADS(0.054) 62.605 0.0039611 18745000 2443 1487.1 1547 1793.1 2085.1 1920.7 1921 1726.2 1861.1 1760.6 TRUE FALSE FALSE 2249.633972 1615.638298 1604.333181 1785.680627 2060.236544 1522.325169 1974.89809 2252.510434 1656.941986 1821.780719 1.234854419 0.886845645 0.880640114 0.980184173 1.130891618 0.835624811 1.084048189 1.236433348 0.909517797 1 10.8311336 -7.258211621 24.96307225 1.110903474 1.000592028 0 0.142387159 461.7370907 3571015.707 0.023983525 0.028734493 5.52E-08 7.258211621 -0.110311446 EEKS(ph)VEYEGDLK ddPTM_HeLa_Curcumin_4h_R1 1 EEKSVEYEGDLK 12 1 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0;H7C3N7 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 EEKS(1)VEYEGDLK 143.93 0.0091064 3857000 834.85 800.28 1032.4 1050.3 887.25 946.87 865.43 632.48 932.12 892.42 TRUE FALSE FALSE 768.7707416 869.4526372 1070.661652 1045.954137 876.6701232 750.4784886 889.7116366 825.3202404 829.868768 923.4315286 0.832515154 0.941545323 1.159438052 1.132681855 0.949361264 0.812706157 0.963484145 0.893753586 0.898679266 1 9.850861181 -4.249298315 21.62933648 0.947644261 0.893753394 0.014811562 0.107697849 1327.283442 2364247.644 0.016907182 0.32394325 5.63E-05 4.249298315 -0.053890867 EELANERLMT(ph)LK ddPTM_HeLa_Curcumin_4h_R1 2 EELANERLMTLK 12 1 C9IZA8;F5H7J3;B4E3Q4;Q9NZK5 C9IZA8 CECR1 Adenosine deaminase CECR1 1 0 EELANERLMT(1)LK;EELANERLMT(1)LK ; 127.78 0.00094708 31578000 6455.8 8534 7932.9 7471.3 5694.1 7771.7 9665.5 5771 7784.9 10443.2 TRUE FALSE FALSE 5944.816618 9271.640933 8226.900252 7440.38574 5626.201576 6159.761815 9936.687917 7530.551334 6930.915947 10806.10042 0.550135237 0.858000627 0.761319989 0.688535683 0.520650499 0.570026335 0.919544288 0.696879636 0.641389185 1 13.39955837 -9.493636204 1.189745511 1.003132248 0.684206016 0 0.163751988 0.358219372 0.892878623 0.095136674 0.022217573 3.21E-10 9.493636204 -0.318926232 EELDMDVMR ddPTM_HeLa_Curcumin_4h_R1 1 EELDMDVMR 9 0 E9PN09;Q6YBV0 E9PN09 SLC36A4 Proton-coupled amino acid transporter 4 0 0 87.639 0.0079746 1255300 1171.6 881.04 774.18 902.18 1009.9 1130.2 985.08 832.4 737.4 882.84 FALSE FALSE TRUE 1078.866624 957.1931718 802.8717918 898.4470182 997.8576021 895.78378 1012.718694 1086.194928 656.5090649 913.5186243 1.181001235 1.047809148 0.878878405 0.983501589 1.092323217 0.980586226 1.108591184 1.189023299 0.718659749 1 9.835290332 -4.426264516 3.92464138 1.056963852 1.184446646 0.02519691 0.133310655 0.360167306 9.215288497 0.013712046 0.092888027 3.75E-05 4.426264516 0.127482794 EELMS(ph)SDLEETAGSTSIPKR ddPTM_HeLa_Curcumin_4h_R1 1 EELMSSDLEETAGSTSIPKR 20 1 O00567 O00567 NOP56 Nucleolar protein 56 1 0 EELMS(0.5)S(0.5)DLEETAGSTSIPKR 76.761 0.0023205 26918000 2195.6 1769 1773.5 2285.5 1900.2 2444.7 1764.2 1381.2 2297.4 2082.9 TRUE FALSE FALSE 2021.815943 1921.904477 1839.22747 2276.043207 1877.541356 1937.641663 1813.698704 1802.321522 2045.380968 2155.28062 0.938075499 0.891718906 0.853358701 1.056031027 0.871135452 0.899020594 0.841513948 0.836235201 0.949009122 1 11.07366001 -1 0.098425671 1.056322759 0.44375542 0.320018771 0.056478073 89.50187876 0.62983808 0.467678261 7.436193286 0.1 1 -0.612567339 EELMSS(ph)DLEETAGSTSIPK ddPTM_HeLa_Curcumin_4h_R1 6 EELMSSDLEETAGSTSIPK 19 0 O00567 O00567 NOP56 Nucleolar protein 56 1 0 EELMS(0.265)S(0.735)DLEETAGSTSIPK;EELMS(0.101)S(0.899)DLEETAGSTSIPK;EELMS(0.16)S(0.84)DLEETAGSTSIPK;EELMS(0.013)S(0.987)DLEETAGSTSIPK;EELMS(0.261)S(0.739)DLEETAGSTSIPK;EELMS(0.051)S(0.949)DLEETAGSTSIPK ;;;;; 189.15 3.73E-10 101545200 32823 27695.4 32847.5 32017 38841.7 35059.7 29427.5 25006.2 28012.8 27537.5 TRUE FALSE FALSE 30225.02492 30089.26697 34064.85725 31884.52214 38378.5381 27787.92302 30253.15645 32630.47527 24939.86592 28494.42608 1.060734645 1.055970276 1.195491959 1.118974008 1.346878789 0.97520557 1.061721909 1.145152921 0.875254194 1 14.79839211 -7.290675422 1.353913295 1.022009883 1.135931041 0.301437436 0.10263234 0.44256753 1.557672292 0.018165147 0.021300913 5.12E-08 7.290675422 0.113921158 EELQANGSAPAADKEEPAAAGS(ph)GAASPSAAEK ddPTM_HeLa_Curcumin_4h_R1 2 EELQANGSAPAADKEEPAAAGSGAASPSAAEK 32 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 EELQANGSAPAADKEEPAAAGS(0.638)GAAS(0.325)PS(0.037)AAEK;EELQANGSAPAADKEEPAAAGS(0.589)GAAS(0.306)PS(0.105)AAEK ; 102.92 2.46E-11 69986000 6148.8 5776.2 7296.2 6308.8 9447.1 9852.5 9964.3 5502.9 5236.9 4638.7 TRUE FALSE FALSE 5662.115992 6275.46899 7566.60359 6282.695857 9334.449503 7808.980439 10243.87144 7180.708878 4662.425172 4799.89448 1.179633431 1.307418114 1.576410403 1.308923745 1.944719731 1.62690669 2.1341868 1.496013904 0.971359931 1 12.22878697 -6.557526196 0.593736193 1.037837512 1.853530069 0.689965539 0.201297293 0.28463621 0.204074687 0.046072577 0.096414862 2.77E-07 6.557526196 0.815692557 EELRQEWEAK ddPTM_HeLa_Curcumin_4h_R1 1 EELRQEWEAK 10 1 B0S8I6;Q14320 B0S8I6 FAM50A Protein FAM50A 0 0 109.83 0.0066227 8033100 3273.3 2736.3 2920.6 2660.4 3574.6 3605.6 3080.6 3074.6 3195.3 2899.3 FALSE FALSE TRUE 3014.214851 2972.813579 3028.840005 2649.39197 3531.97523 2857.757917 3167.033345 4012.031386 2844.783584 3000.050459 1.004721385 0.990921193 1.009596354 0.883115803 1.177305275 0.95256995 1.055660026 1.337321302 0.948245246 1 11.55077105 -4.273094398 3.398063845 1.003200796 1.376228512 0.671302204 0.071190502 0.1143115 2.221344896 0.008393204 0.108406098 5.33E-05 4.273094398 0.373027716 EELSHS(ph)PEPCTK ddPTM_HeLa_Curcumin_4h_R1 1 EELSHSPEPCTK 12 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 0 EELS(0.004)HS(0.996)PEPCTK 73.758 0.015233 10482000 7647 5312.3 6622.4 6368.4 7262.2 6061.2 4600.2 3493.7 6264.9 5376.2 TRUE FALSE FALSE 7041.731881 5771.471541 6867.83197 6342.049248 7175.603008 4804.038796 4729.269231 4558.913047 5577.656144 5563.02255 1.265810415 1.037470456 1.234550446 1.140036588 1.289874874 0.863566299 0.850125842 0.819502888 1.002630511 1 12.44165324 -5.182013414 7.651436526 1.140317384 0.842431005 0.651934283 0.09854727 0.158679366 13.6608142 0.01592205 0.04084185 6.58E-06 5.182013414 -0.297886379 EELTLEGIR ddPTM_HeLa_Curcumin_4h_R1 1 EELTLEGIR 9 0 P60842;J3KT12;P60842-2;J3KSZ0;J3KTB5;J3QS69;J3KTN0 P60842 EIF4A1 Eukaryotic initiation factor 4A-I 0 0 116.25 0.0016385 2129200 563.77 695.21 898.7 618.03 890.94 985.24 655.31 698.86 636.35 733.23 FALSE FALSE TRUE 519.1470096 755.3008546 932.0066126 615.4727556 880.3161224 780.8901181 673.6962349 911.9391968 566.5439971 758.7096879 0.684249876 0.995507065 1.228410059 0.811209828 1.160280587 1.02923441 0.887949957 1.201960659 0.746720394 1 9.567404149 -7.019264598 24.45569048 0.850315905 1.044572013 0.348203419 0.145566133 609.6333044 773906.3338 0.026351596 0.032558629 9.57E-08 7.019264598 0.194256108 EEMAAEAGEAVAS(ph)PMDDGFVSLDSPSYVLYR ddPTM_HeLa_Curcumin_4h_R1 1 EEMAAEAGEAVASPMDDGFVSLDSPSYVLYR 31 0 E9PN85;P49354-2;P49354 E9PN85 FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 1 0 EEMAAEAGEAVAS(0.998)PMDDGFVS(0.002)LDSPSYVLYR 65.284 0.00057016 0 0 0 0 0 145.3 118.33 0 247.97 215.37 0 TRUE FALSE FALSE 0 0 0 0 143.5673924 93.78702415 0 323.5749115 191.7444498 0 0 EEMVLSGK(ac)YK ddPTM_HeLa_Curcumin_4h_R1 1 EEMVLSGKYK 10 1 F8VSD1;G3V1Y1;F8W057;Q9GZN1 F8VSD1 ACTR6 Actin-related protein 6 0 1 EEMVLSGK(1)YK 115.23 0.003716 1790000 1211.4 1373.2 1292.8 1267.6 1390.6 2299.4 1360.7 1660 1495.9 1200.9 FALSE TRUE FALSE 1115.516412 1491.893289 1340.712305 1262.355007 1374.018003 1822.47852 1398.87758 2166.126358 1331.803513 1242.631186 0.897705147 1.200592184 1.078930193 1.015872627 1.105732754 1.466628668 1.125738349 1.743177206 1.071760896 1 10.27918245 -1 0.375533693 0.957579994 10.51661854 0.64958453 0.141115694 22.53069838 0.275027578 0.03461255 158.0356039 0.1 1 9.559038546 EENISAPLISSS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 2 EENISAPLISSSPVK 15 0 A2A2Y4-4;A2A2Y4-3;A2A2Y4-5;A2A2Y4-2;A2A2Y4 A2A2Y4-4 FRMD3 FERM domain-containing protein 3 1 0 EENISAPLIS(0.008)S(0.086)S(0.906)PVK;EENISAPLIS(0.07)S(0.222)S(0.709)PVK ; 128.74 0.00074604 14078300 6596.5 6085 6946 9442.7 6911.5 9361.7 3874.4 2782.1 10526.1 7253.8 TRUE FALSE FALSE 6074.380064 6610.960286 7203.42487 9403.628609 6829.084877 7419.977892 3983.105237 3630.349483 9371.413165 7505.86901 0.809284049 0.880772137 0.959705646 1.25283676 0.909832675 0.988556806 0.530665434 0.483668111 1.248544726 1 12.8738034 -4.754639308 22.06228902 0.938310237 0.507165435 0.61764695 0.149610904 16.6064607 53870.71065 0.01780071 0.063265013 1.76E-05 4.754639308 -0.431144802 EENMDTSNTS(ph)ISK ddPTM_HeLa_Curcumin_4h_R1 2 EENMDTSNTSISK 13 0 Q4G0J3-3;Q4G0J3;H0YA82;D6RFF0 Q4G0J3-3 LARP7 La-related protein 7 1 0 EENMDTSNT(0.005)S(0.979)IS(0.016)K;EENMDTSNT(0.035)S(0.959)IS(0.006)K ; 123.1 0.0022212 18974800 7288.6 7455.6 6475 7811.7 7708.6 11679 10119.5 3558.3 8025.2 7138.4 TRUE FALSE FALSE 6711.699619 8100.028842 6714.969196 7779.377255 7616.67998 9256.643751 10403.42593 4643.20929 7144.855638 7386.458869 0.908649156 1.096605151 0.909091801 1.053194419 1.031167995 1.253190997 1.40844566 0.628610999 0.967291061 1 12.85066717 -5.813854322 2.177580601 0.965821902 1.123737585 0.046773269 0.193577588 0.489277385 4.728651867 0.02729469 0.057579879 1.54E-06 5.813854322 0.157915682 EENPES(ph)DGEPVVEDGTSVK ddPTM_HeLa_Curcumin_4h_R1 1 EENPESDGEPVVEDGTSVK 19 0 Q13439-3;Q13439-4;Q13439;Q13439-5;E7EVX2;H0Y6I0;A0A087WTW2 Q13439-3 GOLGA4 Golgin subfamily A member 4 1 0 EENPES(1)DGEPVVEDGTSVK 213.13 9.10E-49 0 2159.2 2376.8 2382.4 1969.8 2714.9 2086.4 1631.7 612.03 1737.3 1865.1 TRUE FALSE FALSE 1988.297042 2582.240001 2470.69384 1961.64949 2682.526591 1653.657121 1677.481111 798.6351296 1546.722537 1929.912086 1.03025265 1.338009135 1.280210564 1.016445 1.389973466 0.856856192 0.86920079 0.413819435 0.801447148 1 10.91431941 -4.246467128 1.469534452 1.078886955 0.143532463 0.571526565 0.181244016 0.651629811 1.221511196 0.024451187 0.89661129 5.67E-05 4.246467128 -0.935354492 EENPGLT(ph)S(ph)PEPQLPK ddPTM_HeLa_Curcumin_4h_R1 1 EENPGLTSPEPQLPK 15 0 K7EIX9;K7EMC4;A0A0C4DGQ1;Q9BUG6-2;Q9BUG6 K7EIX9 ZSCAN5A Zinc finger and SCAN domain-containing protein 5A 2 0 EENPGLT(1)S(1)PEPQLPK 123.62 0.0047318 6597100 1632.2 1616.3 1467.9 1611 1964.2 3788.7 2932.4 2569.3 2181.5 1664.1 TRUE FALSE FALSE 1503.009648 1756.00577 1522.301665 1604.334109 1940.778198 3002.880913 3014.675252 3352.667742 1942.194908 1721.927351 0.872864727 1.019790857 0.884068462 0.93170836 1.127096446 1.743906856 1.750756354 1.947043666 1.127919193 1 10.74980856 -5.296612809 2.395359874 0.939630201 1.848094251 0.951322613 0.085524125 0.033046976 0.368040022 0.009872292 0.027793965 5.05E-06 5.296612809 0.908464049 EENTSNESTDVTK(ac)GDSK ddPTM_HeLa_Curcumin_4h_R1 1 EENTSNESTDVTKGDSK 17 1 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 0 1 EENTSNESTDVTK(1)GDSK 402.73 0 1501900 570.84 411.54 588.52 639.63 667.72 600.22 450.42 205.18 741.38 563.53 FALSE TRUE FALSE 525.6574117 447.1116838 610.3310689 636.9833805 659.7578751 475.7276061 463.057573 267.7384375 660.0524688 583.1126256 0.901468067 0.766767283 1.046677849 1.09238482 1.131441588 0.815841718 0.79411344 0.459153902 1.131946797 1 9.18763075 -4.279318474 1.508958077 0.96388889 0.281653437 0.658878157 0.117441745 0.507347175 1.07125721 0.016137474 0.508873591 5.26E-05 4.279318474 -0.682235453 EENTSNESTDVTK(ac)GDSK(ac)NAK ddPTM_HeLa_Curcumin_4h_R1 1 EENTSNESTDVTKGDSKNAK 20 2 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 0 2 EENTSNESTDVTK(1)GDSK(1)NAK 271.2 7.44E-95 6131100 4413.2 3465.7 3999.9 3554.8 4561.6 4565.3 3337.4 2171.2 4002.4 3363.4 FALSE TRUE FALSE 4063.890563 3765.259665 4148.139813 3540.091179 4507.205899 3618.405318 3431.038462 2833.188885 3563.346734 3480.2779 1.167691397 1.081884773 1.191899018 1.017186352 1.29507069 1.039688618 0.985851866 0.814069729 1.023868449 1 11.76498679 -4.412984917 1.978086249 1.098306984 0.780076617 0.514148991 0.087569023 0.3687527 1.927301565 0.013191018 0.188935652 3.86E-05 4.412984917 -0.318230367 EENTSNESTDVTK(ac)GDSK(ac)NAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EENTSNESTDVTKGDSKNAKK 21 3 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 0 3 ; EENTSNESTDVTK(1)GDSK(1)NAK(1)K;EENTSNESTDVTK(1)GDSK(1)NAK(1)K 237.09 1.74E-50 8423000 1811.32 1677.95 1842.76 1634.05 1936.42 2423.7 1493.15 1448.41 1883.44 1332.4 FALSE TRUE FALSE 1667.952111 1822.984521 1911.054307 1627.288734 1913.329456 1920.997299 1535.04377 1890.023541 1676.831344 1378.700801 1.209799914 1.322248105 1.386126929 1.180305932 1.387777141 1.393338785 1.113398766 1.370872883 1.216240205 1 10.42909369 -8.38554339 0.64483603 1.007221317 1.307553893 0.263916138 0.110546316 0.335708165 0.297176582 0.046905329 0.022593302 4.12E-09 8.38554339 0.300332576 EENTSNESTDVTKGDSK(ac)NAK ddPTM_HeLa_Curcumin_4h_R1 2 EENTSNESTDVTKGDSKNAK 20 2 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 0 1 ; EENTSNESTDVTK(0.001)GDSK(0.999)NAK;EENTSNESTDVTKGDSK(1)NAK 216.16 1.02E-27 45447000 14068.5 10657.2 11807.1 11876.3 12724.8 12536.3 10355.3 5784.7 12449.9 11605.5 FALSE TRUE FALSE 12954.96338 11578.36088 12244.68151 11827.15902 12573.06507 9936.130067 10645.84185 7548.428401 11084.17712 12008.79026 1.078790044 0.964157141 1.019643215 0.984875142 1.046988481 0.827404747 0.886504104 0.628575255 0.923005305 1 13.5518032 -3.640004458 0.6579877 1.032509543 2.47E-17 0.757160064 0.061530022 1.655514711 0.279609091 0.008746197 1.550054921 0.000229084 3.640004458 -1.032509543 NFELVDSSPCK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 NFELVDSSPCKK 12 1 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 0 1 ; NFELVDSSPCK(1)K;NFELVDSSPCK(1)K 196.67 9.21E-15 3169800 2820.2 2996.8 3409.9 2631 2234.9 3571.5 1104.83 461.82 3153.7 3094.2 FALSE TRUE FALSE 2596.978194 3255.830039 3536.273894 2620.113619 2208.250277 2830.730641 1135.828556 602.626792 2807.747 3201.72322 0.811118893 1.016899281 1.104490817 0.818344822 0.6897068 0.884127217 0.354755386 0.188219515 0.876948695 1 11.64463288 -4.555260632 1.153743053 0.922151793 3.00E-15 0.819469769 0.1180073 0.324737023 0.492744389 0.019009621 0.316158197 2.78E-05 4.555260632 -0.922151793 down EEPCLLK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 EEPCLLKR 8 1 P21333-2;P21333;H0Y5F3;H7C2E7;Q60FE5 P21333-2;Q60FE5 FLNA Filamin-A 0 1 EEPCLLK(1)R 82.241 0.013112 6979700 1389.6 1804.6 1501.3 1329.2 2617 3222.5 2690.8 2438.4 3713.8 1564.6 FALSE TRUE FALSE 1279.611694 1960.581583 1556.939499 1323.700123 2585.793984 2554.117175 2766.296606 3181.856935 3306.405431 1618.969734 0.790386421 1.211005705 0.961685365 0.81761882 1.597184883 1.577618854 1.70867716 1.965359123 2.042289836 1 10.6608603 -5.690620485 4.775836662 0.924236548 1.720238026 0.267036357 0.381507333 0.055387053 2.385304061 0.022791413 0.046066499 2.04E-06 5.690620485 0.796001478 EEPDSENIPQELLSNLGHPES(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 4 EEPDSENIPQELLSNLGHPESPPR 24 0 D6RF40;D6RAG5;D6R9R7;A0A0A0MTL5;Q13309-2;Q13309 D6RF40 SKP2 S-phase kinase-associated protein 2 1 0 EEPDSENIPQELLS(0.218)NLGHPES(0.782)PPR;EEPDSENIPQELLSNLGHPES(1)PPR;EEPDSENIPQELLS(0.007)NLGHPES(0.993)PPR;EEPDSENIPQELLS(0.006)NLGHPES(0.994)PPR ;;; 167.02 5.66E-10 51913400 6201.36 5324.59 5255.82 4903.59 7880.1 7907.7 4993.15 3674.34 5260.68 4799.95 TRUE FALSE FALSE 5710.515812 5784.823834 5450.605313 4883.300244 7786.134954 6267.553882 5133.244351 4794.629351 4683.596566 4966.747905 1.149749478 1.16471058 1.097419361 0.983198732 1.567652537 1.26190296 1.033522226 0.965345824 0.942990596 1 12.27808581 -9.07727158 0.548350264 0.978539058 1.16506991 0.156455217 0.164207976 2.187062838 1.023486271 0.208037264 0.042762183 8.37E-10 9.07727158 0.186530852 EEPEALY(ph)AAVNK ddPTM_HeLa_Curcumin_4h_R1 1 EEPEALYAAVNK 12 0 A0A087WVF7;Q9NZM3-4;Q9NZM3-3;Q9NZM3-2;Q9NZM3 A0A087WVF7 ITSN2 Intersectin-2 1 0 EEPEALY(1)AAVNK 160.77 0.0012527 4119700 1910.4 1909.3 2114.8 1578.9 1958.1 2403.3 1156.2 783.27 1977.4 1211.1 TRUE FALSE FALSE 1759.189824 2074.331384 2193.176348 1572.36693 1934.750936 1904.828489 1188.63986 1022.085417 1760.484167 1253.185635 1.403774329 1.655246698 1.750080984 1.254695942 1.543866194 1.519989087 0.948494642 0.815589797 1.404807172 1 10.29138442 -2.758472029 10.64578881 1.271940669 1.195853101 0 0.305478209 0 0 0.044616668 0 0.001743926 2.758472029 -0.076087568 EEPGS(ph)PLSPAPR ddPTM_HeLa_Curcumin_4h_R1 2 EEPGSPLSPAPR 12 0 B2RBV5 B2RBV5 LOC93622 1 0 EEPGS(0.997)PLS(0.003)PAPR;EEPGS(0.999)PLS(0.001)PAPR ; 166.45 0.00012277 70271000 6504.1 5680.2 6303.8 6289.2 6755.8 8067.4 6137.8 4438.9 6185.9 5563.6 TRUE FALSE FALSE 5989.293622 6171.171178 6537.424373 6263.176957 6675.241497 6394.130302 6310.010149 5792.300176 5507.322246 5756.934686 1.040361572 1.07195435 1.135573831 1.08793608 1.159513154 1.110683141 1.096071172 1.006143111 0.956641433 1 12.49108513 -7.410437166 1.36391662 1.013411183 1.102003571 0.522916886 0.042328773 0.23635756 0.857796221 0.007884785 0.008790366 3.89E-08 7.410437166 0.088592388 EEPLDPEEAEGPLSLVT(ph)TANHSPDFDHDRDYEDEPVNEDME ddPTM_HeLa_Curcumin_4h_R1 1 EEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME 41 1 Q9H334-8;Q9H334-4;A0A3B3IST0;A0A3B3IUB6;A0A3B3IRS5;C9J0F0;Q9H334;Q9H334-3;Q9H334-7;Q9H334-6;A0A3B3IT66;A0A0B4J2F3;A0A3B3IRW5;H0Y882 Q9H334-8 FOXP1 Forkhead box protein P1 1 0 EEPLDPEEAEGPLS(0.085)LVT(0.295)T(0.295)ANHS(0.295)PDFDHDRDY(0.031)EDEPVNEDME 42.756 0.0041791 9357000 1901.9 1770.3 1785.1 1679.2 1955.6 2243.1 1577.8 1085.4 1795.1 1551.9 TRUE FALSE FALSE 1751.362608 1923.316844 1851.257376 1672.251915 1932.280747 1777.855775 1622.068822 1416.333463 1598.182021 1605.828409 1.090628736 1.197710062 1.152836359 1.041364012 1.203292167 1.107126866 1.010113417 0.88199552 0.995238353 1 10.64910203 -4.373506761 2.903750364 1.077152372 0.870332351 0.445254171 0.071805922 0.275452522 3.605247408 0.011252088 0.114950174 4.23E-05 4.373506761 -0.20682002 EEPLDPEEAEGPLSLVTTANHSPDFDHDRDY(ph)EDEPVNEDME ddPTM_HeLa_Curcumin_4h_R1 1 EEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME 41 1 Q9H334-8;Q9H334-4;A0A3B3IST0;A0A3B3IUB6;A0A3B3IRS5;C9J0F0;Q9H334;Q9H334-3;Q9H334-7;Q9H334-6;A0A3B3IT66;A0A0B4J2F3;A0A3B3IRW5;H0Y882 Q9H334-8 FOXP1 Forkhead box protein P1 1 0 EEPLDPEEAEGPLS(0.111)LVT(0.111)T(0.111)ANHS(0.334)PDFDHDRDY(0.335)EDEPVNEDME 42.461 0.0036716 7122900 1222 1068.9 1335.9 1215.4 1476.1 1483.3 1194 630.53 1386.7 994.48 TRUE FALSE FALSE 1125.277411 1161.290953 1385.409629 1210.370997 1458.498472 1175.64686 1227.500427 822.7756944 1234.582479 1029.038106 1.093523558 1.128520845 1.346315186 1.176215914 1.417341557 1.142471647 1.192861974 0.799558043 1.199744181 1 10.00708069 -7.620283256 1.335775793 1.028743217 1.187752533 0 0.162727074 0.501626203 1.828939574 0.03248583 0.032957616 2.40E-08 7.620283256 0.159009316 EEPLS(ph)EEEPCTSTAIAS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 2 EEPLSEEEPCTSTAIASPEK 20 0 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 2 0 EEPLS(0.999)EEEPCT(0.004)S(0.001)T(0.03)AIAS(0.966)PEK;EEPLS(1)EEEPCTSTAIAS(1)PEK ; 148.3 0.00010928 18726700 10175.1 9444.5 10026.1 10404.2 12157.2 9966.2 7399.2 5825.5 8693.5 8492.6 TRUE FALSE FALSE 9369.730098 10260.8405 10397.67609 10361.15018 12012.23333 7899.097778 7606.801638 7601.668133 7739.8448 8787.717218 1.06623027 1.167634352 1.183205584 1.179049111 1.366934442 0.898879377 0.865617481 0.865033312 0.880757153 1 13.10127273 -5.032429791 24.86479551 1.08663553 0.869555984 0.434312141 0.123829841 445.9424234 341916.1594 0.017421638 0.044459319 9.28E-06 5.032429791 -0.217079547 EEPLS(ph)EEEPCTSTAIAS(ph)PEKK ddPTM_HeLa_Curcumin_4h_R1 3 EEPLSEEEPCTSTAIASPEKK 21 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 2 0 EEPLS(1)EEEPCTST(0.002)AIAS(0.998)PEKK;EEPLS(0.998)EEEPCT(0.001)S(0.001)T(0.001)AIAS(0.999)PEKK;EEPLS(0.994)EEEPCT(0.003)S(0.002)T(0.001)AIAS(0.999)PEKK ;; 118.41 5.40E-06 363413000 12764.5 11285.1 13125.7 12597.7 14122.1 13458.8 9690.5 7439.4 11565.4 10215.8 TRUE FALSE FALSE 11754.17636 12260.53376 13612.14999 12545.57406 13953.70318 10667.29317 9962.389349 9707.638813 10296.70456 10570.79829 1.111947843 1.159849372 1.287712585 1.186814251 1.320023597 1.009128438 0.942444371 0.918344911 0.974070668 1 13.36779671 -5.007243146 23.08761992 1.10818127 0.941742381 0.375343499 0.107801839 130.3842441 415617.618 0.017219492 0.048736934 9.83E-06 5.007243146 -0.166438889 EEPLS(ph)EEEPCTSTAIASPEK ddPTM_HeLa_Curcumin_4h_R1 2 EEPLSEEEPCTSTAIASPEK 20 0 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 0 EEPLS(1)EEEPCTSTAIASPEK;EEPLS(1)EEEPCTSTAIASPEK ; 125.37 3.85E-05 25661000 13779.5 11577.6 12766.2 11566.6 14799.6 16934.9 11201.6 10027 11509.6 10230 TRUE FALSE FALSE 12688.83803 12578.31616 13239.3266 11518.74047 14623.12444 13422.41084 11515.88675 13084.18614 10247.02568 10585.49174 1.198700859 1.188259976 1.25070492 1.088163003 1.381430811 1.268000691 1.087893414 1.236048968 0.968025476 1 13.36980067 -9.117225169 0.534968595 0.966753078 1.219709275 0.555942277 0.081441231 0.822775035 0.355703476 0.10527842 0.020303554 7.63E-10 9.117225169 0.252956197 EEPS(ph)QNDISPK ddPTM_HeLa_Curcumin_4h_R1 1 EEPSQNDISPK 11 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 0 EEPS(0.988)QNDIS(0.012)PK 122.34 0.003894 326870000 4439 3729 5126.1 5113.7 4618.6 4866 4199.5 2996.3 5091.8 4004.6 TRUE FALSE FALSE 4087.648466 4051.318144 5316.077775 5092.540864 4563.526212 3856.736749 4317.326668 3909.858077 4533.242279 4143.759552 0.986458894 0.977691416 1.28291174 1.228966305 1.101300921 0.930733722 1.041886387 0.943553319 1.093992598 1 12.01672458 -3.277704253 14.04048746 1.028763867 1.056503886 0 0.116814803 0 0 0.01630244 0 0.000527589 3.277704253 0.027740019 EEPSQNDIS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 EEPSQNDISPK 11 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 0 EEPS(0.012)QNDIS(0.988)PK;EEPSQNDIS(1)PK;EEPS(0.001)QNDIS(0.999)PK ;; 133.04 0.0023898 295007600 9233.4 7776.4 10166.2 9804.3 10073.8 10030.8 8794.7 6002.7 8947 8577.5 TRUE FALSE FALSE 8502.566647 8448.557365 10542.96832 9763.732404 9953.676514 7950.29901 9041.455612 7832.895597 7965.536484 8875.567487 0.957974424 0.95188926 1.187864137 1.100068522 1.121469307 0.895751063 1.018690425 0.882523355 0.897467852 1 13.11562365 -4.257485758 23.72659214 1.005463002 0.882523255 0.149984736 0.092036745 304.9104843 1829675.862 0.012399001 0.124927542 5.53E-05 4.257485758 -0.122939747 EEQLQQILKR ddPTM_HeLa_Curcumin_4h_R1 1 EEQLQQILKR 10 1 H0YJ92;H0YJF2;P51948-2;P51948 H0YJ92 MNAT1 CDK-activating kinase assembly factor MAT1 0 0 74.165 0.01781 2689400 1095.7 1335.3 955.43 1148.6 1542.6 2650.4 1053.8 912.6 1815.9 884.34 FALSE FALSE TRUE 1008.974189 1450.717382 990.8390763 1143.847398 1524.205503 2100.677164 1083.366792 1190.847539 1616.700313 915.0707492 1.102618775 1.585360895 1.082800513 1.250009793 1.665669571 2.295644534 1.183915881 1.301372096 1.76674898 1 9.83773948 -6.821188791 0.691171918 1.02247139 1.588609873 0 0.397830408 0.584399045 0.572358645 0.079783349 0.129607855 1.51E-07 6.821188791 0.566138484 SKPVLEPLT(ph)PPLGS(ph)PRPR ddPTM_HeLa_Curcumin_4h_R1 2 SKPVLEPLTPPLGSPRPR 18 2 Q9H7P9-3;Q9H7P9;H7BXC7;E7ESZ3;Q9H7P9-2 Q9H7P9-3 PLEKHG2 Pleckstrin homology domain-containing family G member 2 2 0 SKPVLEPLT(1)PPLGS(1)PRPR;SKPVLEPLT(1)PPLGS(1)PRPR ; 99.11 0.007987 72534000 5289.5 3846.2 4061.6 4596.4 3930.2 3696.1 2343.4 1026.73 5460.8 4177.4 TRUE FALSE FALSE 4870.830494 4178.64839 4212.126469 4577.381315 3883.334932 2929.487196 2409.149497 1339.775251 4861.763902 4322.564339 1.126838171 0.966705886 0.974450844 1.058950418 0.898386843 0.677719744 0.557342658 0.309949175 1.124740668 1 12.07767172 -4.729274814 0.837717488 1.054103944 0.15755783 0.950801087 0.056676662 0.217559937 0.16780822 0.010308119 0.154403996 1.87E-05 4.729274814 -0.896546114 down EES(ph)DEEEEDDEESGR ddPTM_HeLa_Curcumin_4h_R1 1 EESDEEEEDDEESGR 15 0 Q96EV2;A8MTF7;Q96EV2-2;H7BXM6;H7C0H2 Q96EV2 RBM33 RNA-binding protein 33 1 0 EES(1)DEEEEDDEESGR 254.94 4.67E-39 1573100 355.12 149.37 359.14 316.79 401.29 311.09 367.36 331.91 192.08 457.01 TRUE FALSE FALSE 327.0118773 162.2808772 372.4500443 315.4792069 396.5048788 246.5664273 377.6671329 433.1078311 171.0093046 472.8910635 0.691516297 0.34316757 0.787602205 0.667128714 0.838469807 0.521402171 0.798634531 0.915872311 0.361625156 1 8.885364068 -9.00201079 0.962976867 0.98798554 0.692837349 0 0.25028154 0.44687843 0.791782995 0.082143666 0.029755998 9.95E-10 9.00201079 -0.295148191 EES(ph)DGEYDEFGR ddPTM_HeLa_Curcumin_4h_R1 2 EESDGEYDEFGR 12 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 EES(1)DGEYDEFGR;EES(1)DGEYDEFGR ; 206.74 4.43E-09 363470000 3510.7 3332.8 3248.4 3159.4 3344.5 3932.4 3100.7 3771.6 3685.4 3052.5 TRUE FALSE FALSE 3232.824391 3620.872381 3368.788562 3146.32724 3304.619022 3116.775913 3187.697297 4921.543478 3281.12084 3158.574148 1.023507519 1.146362951 1.066553579 0.996122647 1.046237596 0.986766739 1.009220347 1.558153536 1.038798105 1 11.62505772 -4.260501194 24.99942581 1.023649503 1.558153704 0.922801306 0.04530413 15.14328366 403454.0515 0.006562438 0.053242506 5.49E-05 4.260501194 0.534504201 EES(ph)DGEYDEFGRK ddPTM_HeLa_Curcumin_4h_R1 2 EESDGEYDEFGRK 13 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 EES(1)DGEYDEFGRK;EES(1)DGEYDEFGRK ; 96.673 0.0041001 179167000 6216.8 4081.7 5694.2 4756.2 4966.6 4847.2 3879.6 3955.5 3972.9 3844.2 TRUE FALSE FALSE 5724.73372 4434.50396 5905.232061 4736.520105 4907.376539 3841.836081 3988.451135 5161.513741 3537.08281 3977.785664 1.439176015 1.114817221 1.484552603 1.190742917 1.233695567 0.965822798 1.002681258 1.297584681 0.889208999 1 11.95774983 -5.296412582 23.11553679 1.226282835 1.080094711 0.040391092 0.188929856 418.1424677 276370.5742 0.027795184 0.062156396 5.05E-06 5.296412582 -0.146188124 EES(ph)EDELEEANGNNPIDIEVDQNK ddPTM_HeLa_Curcumin_4h_R1 1 EESEDELEEANGNNPIDIEVDQNK 24 0 Q9UKL0 Q9UKL0 RCOR1 REST corepressor 1 1 0 EES(1)EDELEEANGNNPIDIEVDQNK 149.91 2.70E-07 5198100 1499.3 1323.9 1483.3 1775.9 1541.6 1712.6 1357 1314 1653.4 1422.9 TRUE FALSE FALSE 1380.628823 1438.332017 1538.272403 1768.551796 1523.217427 1357.387455 1395.073768 1714.632551 1472.026157 1472.345669 0.937706988 0.976898324 1.044776668 1.201179746 1.034551504 0.921921722 0.947517826 1.164558423 0.999782991 1 10.5239007 -6.770783941 6.098941655 0.970061414 1.047860481 0.161252522 0.08128593 0.223236847 30.59666422 0.01356182 0.01841587 1.70E-07 6.770783941 0.077799068 EES(ph)EEEEDEDDEEEEEEEKEK ddPTM_HeLa_Curcumin_4h_R1 7 EESEEEEDEDDEEEEEEEKEK 21 1 A0A494C198;B4DFG0;H0Y993;P35659;D6R9L5;H0Y8X0;A0A494C028 A0A494C198 DEK Protein DEK 1 0 EES(1)EEEEDEDDEEEEEEEKEK;EES(1)EEEEDEDDEEEEEEEKEK;EES(1)EEEEDEDDEEEEEEEKEK;EES(1)EEEEDEDDEEEEEEEKEK;EES(1)EEEEDEDDEEEEEEEKEK;EES(1)EEEEDEDDEEEEEEEKEK;EES(1)EEEEDEDDEEEEEEEKEK ;;;;;; 158.78 5.70E-07 2462613100 11108.89 10242.67 11089.89 10361.75 13842.04 12186.12 10812.03 11115.79 10017.43 9753.61 TRUE FALSE FALSE 10229.60963 11128.00075 11500.89108 10318.87582 13676.98271 9658.581346 11115.38646 14504.9432 8918.542991 10092.54722 1.013580557 1.102595857 1.139542954 1.02242532 1.355156673 0.957001353 1.101345995 1.437193494 0.883676122 1 13.30100272 -1 0.280134916 1.001003121 3.309403665 0.406036851 0.126893055 36.80487068 0.46905559 0.049551056 42.15330341 0.1 1 2.308400544 EES(ph)EES(ph)EAEPVQR ddPTM_HeLa_Curcumin_4h_R1 3 EESEESEAEPVQR 13 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 2 0 EES(1)EES(1)EAEPVQR;EES(1)EES(1)EAEPVQR;EES(1)EES(1)EAEPVQR ;; 115.06 0.0070755 118507000 5641.1 5343.1 5633.6 5679.6 5630.3 6470 6211.7 4495.67 5501.9 5896.9 TRUE FALSE FALSE 5194.600983 5804.933756 5842.386172 5656.09932 5563.16235 5128.049068 6385.983584 5866.379087 4898.355335 6101.816836 0.851320373 0.951345134 0.957483046 0.926953311 0.911722279 0.840413471 1.046570842 0.96141514 0.802769973 1 12.57502316 -4.740247774 24.99531966 0.925625382 1.003992968 0.239901347 0.062373545 294.9006094 347827.2744 0.008581403 0.032042922 1.82E-05 4.740247774 0.078367586 EES(ph)EESEAEPVQR ddPTM_HeLa_Curcumin_4h_R1 2 EESEESEAEPVQR 13 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 0 EES(0.69)EES(0.31)EAEPVQR;EES(0.987)EES(0.013)EAEPVQR ; 206.45 4.83E-09 73805000 3015 2333.5 2804.1 2446.2 2997.7 2320.02 2028.69 2026.87 2519.35 2209.6 TRUE FALSE FALSE 2776.359569 2535.197342 2908.022413 2436.078273 2961.954385 1838.8217 2085.609581 2644.853332 2242.983608 2286.383436 1.214301821 1.108824226 1.271887457 1.065472324 1.295475789 0.804249047 0.912187146 1.156784681 0.981018132 1 11.15885165 -5.257186963 24.99755344 1.125549926 0.95318499 0.28252592 0.128071568 380.6074475 2237363.111 0.018276498 0.044858299 5.53E-06 5.257186963 -0.172364936 EES(ph)EPEVKEDVIEK ddPTM_HeLa_Curcumin_4h_R1 1 EESEPEVKEDVIEK 14 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 EES(1)EPEVKEDVIEK 74.338 0.011627 5244500 1934.5 1583.3 2175.5 1614.7 1871.6 1788.4 1668.5 1779.2 1275.6 1403.9 TRUE FALSE FALSE 1781.382284 1720.153397 2256.125944 1608.018799 1849.282392 1417.465681 1715.313619 2321.66989 1135.669871 1452.685421 1.22626844 1.184119681 1.553072614 1.106928435 1.273009535 0.975755425 1.180788074 1.598191774 0.781772747 1 10.50450661 -8.894414416 0.671170528 0.99215081 1.255578574 0.33939342 0.192729037 0.931038123 0.759004108 0.132315066 0.039292931 1.28E-09 8.894414416 0.263427764 EES(ph)PTRINGSIPAGPK ddPTM_HeLa_Curcumin_4h_R1 1 EESPTRINGSIPAGPK 16 1 Q8N6T7-2;Q8N6T7;M0QZ09 Q8N6T7-2 SIRT6 NAD-dependent protein deacetylase sirtuin-6 1 0 EES(0.957)PT(0.041)RINGS(0.001)IPAGPK 80.238 0.0054465 16589000 1849.2 1486.1 1612.6 1638 1609.4 1716.7 1676.4 1411.8 1888.4 1912.7 TRUE FALSE FALSE 1702.833869 1614.551862 1672.364375 1631.22239 1590.208956 1360.637069 1723.435272 1842.251321 1681.247245 1979.166183 0.860379428 0.815773772 0.844984312 0.824196778 0.803474195 0.68747995 0.870788561 0.930821948 0.8494725 1 10.95067704 -8.676528784 0.555092131 1.008823553 0.817418179 0.093592716 0.073743487 0.536418368 0.315304273 0.049495869 0.016190988 2.11E-09 8.676528784 -0.191405374 EES(ph)REPAPASPAPAGVEIR ddPTM_HeLa_Curcumin_4h_R1 2 EESREPAPASPAPAGVEIR 19 1 Q14195-2 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 1 0 EES(1)REPAPASPAPAGVEIR;EES(1)REPAPASPAPAGVEIR ; 140.88 8.77E-05 20764000 2496.92 1864.54 2638.8 2315.26 2213.87 2855.48 2106.56 2756.67 2339.09 2355.02 TRUE FALSE FALSE 2299.286147 2025.702529 2736.596249 2305.680068 2187.471046 2263.22126 2165.664404 3597.165993 2082.497679 2436.85677 0.943545873 0.831276813 1.123002502 0.946169712 0.897660902 0.928746116 0.888712226 1.476149948 0.854583538 1 11.25080574 -4.2566612 24.97866936 0.959289774 1.47615016 0.796643486 0.081204766 148.2541586 774994.4316 0.009906658 0.107834987 5.54E-05 4.2566612 0.516860386 EES(ph)WGPPR ddPTM_HeLa_Curcumin_4h_R1 2 EESWGPPR 8 0 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 0 EES(1)WGPPR;EES(1)WGPPR ; 120.27 0.0081895 38993000 4248.3 4455.1 4172.3 4335.6 3950.9 4336.6 2861 2322.9 3514.1 4242 TRUE FALSE FALSE 3912.042572 4840.178992 4326.929108 4317.660436 3903.788098 3437.140276 2941.27196 3031.141517 3128.612022 4389.409184 0.891245816 1.102694871 0.985765721 0.983654122 0.889365273 0.783053056 0.670083794 0.690557975 0.712763812 1 12.09981105 -5.190223513 1.792658647 0.965455321 0.67656866 0.546198522 0.095893191 0.126841913 0.769070998 0.009321582 0.033340703 6.45E-06 5.190223513 -0.288886661 EESEES(ph)DEDMGFGLFD ddPTM_HeLa_Curcumin_4h_R1 3 EESEESDEDMGFGLFD 16 0 F8VWS0;P05388-2;Q8NHW5;P05388;F8W1K8 F8VWS0 RPLP0;RPLP0P6 60S acidic ribosomal protein P0;60S acidic ribosomal protein P0-like 1 0 EES(0.005)EES(0.995)DEDMGFGLFD;EES(0.003)EES(0.997)DEDMGFGLFD;EES(0.004)EES(0.996)DEDMGFGLFD ;; 113.76 0.0015668 59704600 5475.99 4690.68 4838.19 5370.54 5073.72 6057.59 4646.75 5236.73 5235.3 5050.98 TRUE FALSE FALSE 5042.559613 5096.121478 5017.497578 5348.318128 5013.219203 4801.177551 4777.125299 6833.38487 4661.000688 5226.501179 0.964805984 0.975054114 0.9600108 1.023307552 0.959192207 0.918621729 0.91401975 1.307449216 0.891801327 1 12.35162976 -4.255090672 24.99163064 0.974221875 1.307449365 0.863397714 0.041352073 163.3738653 643101.9516 0.004784374 0.06039193 5.56E-05 4.255090672 0.33322749 EESEES(ph)EAEPVQR ddPTM_HeLa_Curcumin_4h_R1 2 EESEESEAEPVQR 13 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 0 EES(0.214)EES(0.786)EAEPVQR;EES(0.241)EES(0.759)EAEPVQR ; 206.74 4.61E-09 78748000 3992.5 2893.5 3245.9 2880.2 3312.9 2949.1 2390.7 2203.63 3011.1 2436 TRUE FALSE FALSE 3676.489412 3143.601247 3366.195909 2868.282496 3273.395831 2337.423417 2457.776608 2875.506643 2680.789863 2520.650819 1.458547683 1.247138724 1.335447133 1.13791346 1.298631213 0.927309487 0.975056358 1.140779445 1.063530832 1 11.29958056 -5.263944155 24.98073018 1.231379793 1.01044922 0.324982402 0.13520468 239.235241 2385962.275 0.025544333 0.059759393 5.45E-06 5.263944155 -0.220930573 EESEESDEDMGFGLFD ddPTM_HeLa_Curcumin_4h_R1 2 EESEESDEDMGFGLFD 16 0 F8VWS0;P05388-2;Q8NHW5;P05388;F8W1K8 F8VWS0 RPLP0;RPLP0P6 60S acidic ribosomal protein P0;60S acidic ribosomal protein P0-like 0 0 ; ; 196.27 1.52E-06 3847900 3194.2 2890.97 2826.9 3026 2799.1 3408.3 2583.97 3948.7 3481.1 2594.06 FALSE FALSE TRUE 2941.375699 3140.852565 2931.667401 3013.479214 2765.722561 2701.380161 2656.469244 5152.640452 3099.232039 2684.203392 1.095809546 1.170124654 1.092192719 1.122671711 1.030369967 1.006399205 0.989667643 1.919616251 1.154618927 1 11.39027828 -4.258750532 24.99988329 1.056343457 1.919616558 0.94043741 0.063746165 40.66691645 378083.905 0.008918562 0.082205478 5.51E-05 4.258750532 0.863273101 EESGKPGAHVTVK ddPTM_HeLa_Curcumin_4h_R1 1 EESGKPGAHVTVK 13 1 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 56.951 0.016765 12136000 12370 10970 9565.9 8874.2 18374 27341 15287 12941 17491 10277 FALSE FALSE TRUE 11390.90145 11918.19792 9920.420669 8837.480912 18154.90205 21670.1684 15715.91208 16886.65133 15572.28106 10634.12499 1.071164902 1.12075022 0.932885469 0.831049186 1.707230456 2.037795158 1.477875434 1.587968107 1.46436882 1 13.37641371 -5.75145969 24.99911029 1.020597054 1.710591492 0.687530801 0.207324394 60.37007559 151225.8541 0.022113687 0.043812318 1.77E-06 5.75145969 0.689994438 EESGKPGAHVTVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EESGKPGAHVTVKK 14 2 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 1 ; EESGKPGAHVTVK(1)K;EESGKPGAHVTVK(1)K 147.39 0.00022417 69724200 11828.6 10028.9 6766.8 5895.7 14169.3 27475.7 13391.6 13904.9 16706.3 8574.6 FALSE TRUE FALSE 10892.35383 10895.75343 7017.583561 5871.305156 14000.34035 21776.93011 13767.33225 18144.44 14873.66069 8872.566712 1.227644061 1.228027219 0.790930493 0.661736941 1.577935766 2.454411538 1.551674132 2.045004629 1.676365044 1 13.1151358 -5.537382048 7.724451871 1.067220166 1.978925508 0.612416116 0.328814878 0.058825911 19.75195268 0.038239686 0.07815204 2.90E-06 5.537382048 0.911705342 EESIS(ph)LMK ddPTM_HeLa_Curcumin_4h_R1 1 EESISLMK 8 0 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1 0 EESIS(1)LMK 101.64 0.016431 12189000 3624.5 2747.2 3081.5 2937.6 3131.9 4290.1 3266.5 3080.4 2997.3 2271 TRUE FALSE FALSE 3337.617 2984.655727 3195.703101 2925.44499 3094.554138 3400.284901 3358.149199 4019.59978 2668.503689 2349.917081 1.420312669 1.270111082 1.359921644 1.244914135 1.316878014 1.446980801 1.429050083 1.710528347 1.135573553 1 11.19839414 -12.31713784 0.175751546 4.18E-16 1.513679765 0.613559621 0.113767788 18.02195385 0.298936801 6.635798936 0.188230276 4.82E-13 12.31713784 1.513679765 AVSLDS(ph)PVSVGSSPPVK ddPTM_HeLa_Curcumin_4h_R1 2 AVSLDSPVSVGSSPPVK 17 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 0 AVS(0.001)LDS(0.997)PVS(0.002)VGSSPPVK;AVS(0.001)LDS(0.999)PVSVGSSPPVK ; 217.39 1.50E-15 71550000 12366.9 8533 12183.1 11369.6 11028.7 13214.5 13249.8 17310.1 9337.9 10783.1 TRUE FALSE FALSE 11388.04682 9270.554498 12634.6164 11322.55561 10897.18996 10473.66374 13621.55373 22587.8698 8313.555732 11157.81192 1.020634412 0.830857749 1.132356101 1.014764874 0.976642198 0.938684378 1.220808687 2.024399583 0.745088355 1 13.44576652 -4.273098851 2.683894448 1.000444907 2.211821202 0.895556476 0.108754916 0.062937715 0.605675074 0.009449937 0.167122348 5.33E-05 4.273098851 1.211376295 up EESREPAPASPAPAGVEIR ddPTM_HeLa_Curcumin_4h_R1 1 EESREPAPASPAPAGVEIR 19 1 Q14195-2 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 0 0 134.82 0.00022038 2621800 1988 2072.7 2706.5 2572.8 2320.7 1481.3 1902.8 1653.9 2810.5 2579.6 FALSE FALSE TRUE 1830.647702 2251.854952 2806.805271 2562.154435 2293.027168 1174.061682 1956.187447 2158.166496 2502.195182 2669.240908 0.685830828 0.843631216 1.051536885 0.959881301 0.859055907 0.439848527 0.73286283 0.808531928 0.937418265 1 11.3822138 -5.476277538 24.9058995 0.872484211 0.664624632 0.40837786 0.131048411 415.726102 222183.2956 0.022641009 0.050625249 3.34E-06 5.476277538 -0.207859578 EESTAASETTEGSQGDSK(ac)NAK(ac)K(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EESTAASETTEGSQGDSKNAKKK 23 3 Q92793;Q92793-2 Q92793 CREBBP CREB-binding protein 0 3 ; EESTAASETTEGSQGDSK(1)NAK(1)K(1)K;EESTAASETTEGSQGDSK(1)NAK(1)K(1)K 265.09 7.36E-81 5895500 2652.9 2023.2 2241.3 1849.79 2921.7 3052 2035.45 945.97 1982.62 1814.08 FALSE TRUE FALSE 2442.920166 2198.076393 2324.36455 1842.136059 2886.860636 2418.980797 2092.559249 1234.391898 1765.131546 1877.119145 1.301419876 1.170983951 1.238261597 0.981363417 1.537920831 1.288666627 1.114771673 0.65759912 0.940340708 1 10.87430451 -4.272656361 4.012040856 1.17929989 0.616442101 0.459270632 0.169646987 0.155745178 5.225882909 0.023639051 0.249390266 5.34E-05 4.272656361 -0.562857789 EESTSSGNVSNR ddPTM_HeLa_Curcumin_4h_R1 2 EESTSSGNVSNR 12 0 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 0 0 ; ; 149.23 5.53E-05 908940 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 EETDKEEPASK(ac)QQK ddPTM_HeLa_Curcumin_4h_R1 2 EETDKEEPASKQQK 14 2 P05455 P05455 SSB Lupus La protein 0 1 ; EETDKEEPASK(1)QQK;EETDKEEPASK(1)QQK 201.48 7.42E-15 5403000 2757.3 1894.28 1901.79 2034.15 2754.25 3182.83 2265.66 2792.02 2118.51 1885.58 FALSE TRUE FALSE 2539.056796 2058.013122 1972.27201 2025.733226 2721.407368 2522.67518 2329.228322 3643.294045 1886.114753 1951.103765 1.301343804 1.054794296 1.01084937 1.038249868 1.394804017 1.292947728 1.193800332 1.867298967 0.966691156 1 10.93007479 -1.436275255 0.95629733 1.136097026 199.9999982 0.708153291 0.140686177 227.1280425 0.942529463 0.023494629 98064.71613 0.03662054 1.436275255 198.8639011 EETQPPVALK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 EETQPPVALKK 11 1 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 1 EETQPPVALK(1)K 192.12 1.22E-16 12805000 4435.3 5326.7 4375.8 4276 7277.3 9201.7 6812.1 5596.9 8482.8 3979.7 FALSE TRUE FALSE 4084.241325 5787.116213 4537.970997 4258.307045 7190.52295 7293.163695 7003.229192 7303.369045 7552.258063 4117.994279 0.991803545 1.405324005 1.101985746 1.034073084 1.746122618 1.771047554 1.700640826 1.773525787 1.833965166 1 12.00772611 -5.761081478 24.99139552 1.04133168 1.746121451 0.363078966 0.277865437 2.367567951 165298.3846 0.019398712 0.03695962 1.73E-06 5.761081478 0.704789772 EETQPPVALKK ddPTM_HeLa_Curcumin_4h_R1 1 EETQPPVALKK 11 1 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 0 84.687 0.0086118 0 3519.3 2999.8 3148.6 3640.3 3440.6 4327.9 3323.2 3937.9 3470 3298.9 FALSE FALSE TRUE 3240.743691 3259.089345 3265.289886 3625.237403 3399.573092 3430.244755 3416.440048 5138.547582 3089.349682 3413.536529 0.949380112 0.954754495 0.956570951 1.062018048 0.995909393 1.004894696 1.00085059 1.505344249 0.905029038 1 11.73705148 -4.260462351 5.336664087 0.982403132 1.526694725 0.939870349 0.039809991 0.022727914 2.309186771 0.004867936 0.045078572 5.49E-05 4.260462351 0.544291593 EEVVEQGELNATEEVWIPGEGHPES(ph)PEPK ddPTM_HeLa_Curcumin_4h_R1 2 EEVVEQGELNATEEVWIPGEGHPESPEPK 29 0 P48681 P48681 NES Nestin 1 0 EEVVEQGELNAT(0.095)EEVWIPGEGHPES(0.905)PEPK;EEVVEQGELNATEEVWIPGEGHPES(1)PEPK ; 146.65 2.11E-12 15295200 3849 3392.8 3474.76 3652.89 3998.19 3610.6 3128.3 3647 3752.7 3235.8 TRUE FALSE FALSE 3544.347589 3686.058514 3603.537662 3637.775309 3950.514196 2861.72086 3216.071679 4758.953511 3341.038199 3348.243809 1.058569146 1.100893102 1.076247092 1.086472645 1.179876503 0.854693094 0.960524938 1.421328249 0.997847943 1 11.70918887 -4.25456298 24.8520649 1.035475819 1.421328442 0.654499971 0.084203138 348.0943202 1258015.799 0.011542385 0.15125216 5.56E-05 4.25456298 0.385852624 EEVVQKEQE ddPTM_HeLa_Curcumin_4h_R1 1 EEVVQKEQE 9 1 Q15056;Q15056-2 Q15056 EIF4H Eukaryotic translation initiation factor 4H 0 0 161.79 2.09E-07 4695300 3290.9 2865.8 2631.6 3229.8 2866.3 3495.6 3199.8 3200.1 3651.3 3162.2 FALSE FALSE TRUE 3030.421792 3113.506982 2729.129411 3216.435943 2832.121245 2770.573156 3289.577776 4175.795759 3250.761525 3272.086215 0.926143626 0.951535741 0.834064029 0.982992419 0.865539921 0.846729877 1.005345691 1.276187571 0.993482846 1 11.67599505 -4.292115772 3.585357858 0.941532005 1.304462167 0.756190227 0.059136862 0.100775558 2.306465536 0.008727006 0.093017044 5.10E-05 4.292115772 0.362930163 EEYEGPNK(ac)KPR ddPTM_HeLa_Curcumin_4h_R1 1 EEYEGPNKKPR 11 2 P23246 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 1 EEYEGPNK(0.897)K(0.103)PR 114.86 0.00067382 63472000 7486.6 6339.8 6396.5 6594.7 7344.2 8801.6 7892.4 9261.5 7371.9 5937.9 FALSE TRUE FALSE 6894.02771 6887.784062 6633.559917 6567.412879 7256.625212 6976.048946 8113.839503 12085.28872 6563.221014 6144.241583 1.122030704 1.121014525 1.079638525 1.068872828 1.181044904 1.13537999 1.320559974 1.966929287 1.068190585 1 12.58501923 EEYEGPNKK(ac)PR ddPTM_HeLa_Curcumin_4h_R1 1 EEYEGPNKKPR 11 2 P23246 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 1 EEYEGPNK(0.053)K(0.947)PR 127.51 0.00025165 65565000 5849.5 4875.9 5535.2 4978.8 5835.1 7421 6215.6 8027.2 6016.2 5354.3 FALSE TRUE FALSE 5386.505903 5297.351069 5740.339381 4958.199045 5765.520244 5881.800948 6389.993008 10474.65633 5356.237912 5540.361526 0.972230039 0.956138159 1.03609473 0.894923377 1.040639716 1.061627643 1.153353076 1.890608813 0.966766859 1 12.4357644 -3.974612565 1.560726182 0.985619724 2.895378851 0.972936273 0.044864702 0.23292354 0.296494499 0.006002992 0.840773642 0.00010602 3.974612565 1.909759128 EFAGEDT(ph)SDLFLEER ddPTM_HeLa_Curcumin_4h_R1 2 EFAGEDTSDLFLEER 15 0 O14980 O14980 XPO1 Exportin-1 1 0 EFAGEDT(0.5)S(0.5)DLFLEER;EFAGEDT(0.5)S(0.5)DLFLEER ; 188.19 1.48E-05 13172600 3529.14 3657.72 3781.3 3449.49 3788.67 4758.5 3519.56 3956.83 3150.43 3579.89 TRUE FALSE FALSE 3249.804845 3973.877018 3921.438304 3435.216924 3743.492585 3771.533461 3618.309381 5163.249252 2804.835711 3704.290911 0.877308214 1.072776711 1.058620502 0.92736154 1.010582774 1.01815261 0.976788667 1.393856308 0.757185593 1 11.85498169 -4.260355588 5.920284903 0.967454878 1.406150406 0.675889369 0.088794808 0.049305793 7.944805065 0.009830535 0.086414044 5.49E-05 4.260355588 0.438695527 EFAPS(ph)DEELDSYR ddPTM_HeLa_Curcumin_4h_R1 2 EFAPSDEELDSYR 13 0 I3L0X5;O75391;I3L4C3 I3L0X5 SPAG7 Sperm-associated antigen 7 1 0 EFAPS(1)DEELDSYR;EFAPS(0.993)DEELDS(0.007)YR ; 244.71 4.03E-27 106754000 7876.8 6425.9 7222.8 6860 7028.3 8388.6 6485.9 4617.6 6789.2 6066.8 TRUE FALSE FALSE 7253.342968 6981.326163 7490.483322 6831.615138 6944.492113 6648.709801 6667.876898 6025.484983 6044.441746 6277.620848 1.155428648 1.112097454 1.193204162 1.088249084 1.106229937 1.059112992 1.062166234 0.959835761 0.962855498 1 12.61600218 -3.897261479 1.321181262 1.089576837 0.782553743 0.256262403 0.06371926 3.511230963 2.783533084 0.010053014 1.826673039 0.000126689 3.897261479 -0.307023094 EFAPS(ph)DEELDSYRR ddPTM_HeLa_Curcumin_4h_R1 3 EFAPSDEELDSYRR 14 1 I3L0X5;O75391;I3L4C3 I3L0X5 SPAG7 Sperm-associated antigen 7 1 0 EFAPS(1)DEELDSYRR;EFAPS(0.743)DEELDS(0.039)Y(0.218)RR;EFAPS(1)DEELDSYRR ;; 125.39 0.00062833 19977100 7308.1 6330.1 6979.7 7403.4 6958.2 8215.8 6475.9 5447.44 7861.8 7083 TRUE FALSE FALSE 6729.656174 6877.245638 7238.373822 7372.766692 6875.22801 6511.750469 6657.596325 7108.339379 6999.380209 7329.133723 0.91820622 0.938343588 0.987616558 1.00595336 0.9380683 0.88847478 0.908374247 0.969874428 0.955007846 1 12.83942697 EFAPSDEELDSYR ddPTM_HeLa_Curcumin_4h_R1 2 EFAPSDEELDSYR 13 0 I3L0X5;O75391;I3L4C3 I3L0X5 SPAG7 Sperm-associated antigen 7 0 0 ; ; 234.9 5.04E-19 18050500 2066.73 1812.47 1905.97 1775.71 1876.23 2894.6 2061 1985.54 2269 1930.44 FALSE FALSE TRUE 1903.14614 1969.131831 1976.606925 1768.362583 1853.857183 2294.227331 2118.826113 2590.922006 2020.096377 1997.522646 0.952753223 0.985786987 0.989529169 0.885277864 0.92807818 1.148536331 1.060726954 1.297067651 1.011300863 1 10.96399614 -3.992749155 0.937998223 0.971015096 1.597498232 0.741000671 0.057643889 1.146615634 0.545853143 0.008643837 0.820249275 0.000101684 3.992749155 0.626483136 EFDEDS(ph)DEKEEEEDTYEK ddPTM_HeLa_Curcumin_4h_R1 1 EFDEDSDEKEEEEDTYEK 18 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 EFDEDS(0.994)DEKEEEEDT(0.005)Y(0.002)EK 61.524 0.011372 62180000 4142.1 4056.5 4850.6 3623.4 5170.5 3787.8 3868.8 3672.2 3328.1 4272 TRUE FALSE FALSE 3814.248414 4407.125785 5030.367503 3608.407331 5108.845164 3002.167583 3977.348116 4791.836875 2963.015756 4420.451682 0.862863953 0.996985399 1.137975905 0.816298331 1.155729218 0.679154032 0.899760568 1.084015214 0.670297058 1 12.10997808 -4.25103473 23.59844589 0.939590075 1.084015366 0.072444255 0.160011392 1261.329949 2860651.419 0.0176089 0.311957027 5.61E-05 4.25103473 0.14442529 EFDPTITDASLS(ph)LPSRR ddPTM_HeLa_Curcumin_4h_R1 2 EFDPTITDASLSLPSRR 17 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1;C9J813 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 1 0 EFDPTITDAS(0.084)LS(0.907)LPS(0.009)RR;EFDPTITDAS(0.04)LS(0.959)LPSRR ; 133.35 0.00015877 11196600 3539.4 3130.9 3515.9 3361.7 3780.8 5148.1 3986.2 4376.4 3371.6 3417.8 TRUE FALSE FALSE 3259.252755 3401.521045 3646.202347 3347.790176 3735.716429 4080.326029 4098.042044 5710.744214 3001.743915 3536.568296 0.921586262 0.961814041 1.031000123 0.946621102 1.056311123 1.153752929 1.158762309 1.614769951 0.848773066 1 11.78813441 -1.000000003 0.674777024 0.965448974 68.17683253 0.918131071 0.058370436 36.51455153 0.199256704 0.007969115 3691.919827 0.099999999 1.000000003 67.21138356 EFETIERDER ddPTM_HeLa_Curcumin_4h_R1 1 EFETIERDER 10 1 Q10570 Q10570 CPSF1 Cleavage and polyadenylation specificity factor subunit 1 0 0 86.67 0.0093385 0 1559 1289 1269.4 1508.2 1416.4 1785.7 1295.7 1309.6 1489 1333.6 FALSE FALSE TRUE 1435.603505 1400.415416 1316.445081 1501.959468 1399.510355 1415.325691 1332.053855 1708.891011 1325.660425 1379.942501 1.040335742 1.014836064 0.95398546 1.088421776 1.014180195 1.025641061 0.965296637 1.238378418 0.960663524 1 10.43039244 -4.253175818 24.90929092 1.016836525 1.238378534 0.749484056 0.039762715 332.731238 1002945.266 0.004672085 0.070899979 5.58E-05 4.253175818 0.221542009 EFGSLPTT(ph)PSEQR ddPTM_HeLa_Curcumin_4h_R1 1 EFGSLPTTPSEQR 13 0 O15400-2;O15400 O15400-2 STX7 Syntaxin-7 1 0 EFGSLPT(0.045)T(0.942)PS(0.014)EQR 135.91 0.0036432 10364000 2949.9 2338 2710 2870.1 2848.6 4245.9 2416.9 2312.3 3253.7 3261.3 TRUE FALSE FALSE 2716.412302 2540.086302 2810.434984 2858.224287 2814.632305 3365.252479 2484.711709 3017.309625 2896.77725 3374.629932 0.804951167 0.752700697 0.832812794 0.846974141 0.834056582 0.997221191 0.736291611 0.894115706 0.858398494 1 11.72051359 -9.272769944 1.004901338 0.99986233 0.835558502 0.076836623 0.0808711 0.386456963 0.700595166 0.044950848 0.012243386 5.34E-10 9.272769944 -0.164303828 PIPQT(ph)PESAGNK ddPTM_HeLa_Curcumin_4h_R1 1 PIPQTPESAGNK 12 0 A0A3B3ITD8;P52948-6;P52948-2;P52948-5;P52948;P52948-4;P52948-3 A0A3B3ITD8 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 0 PIPQT(0.976)PES(0.024)AGNK 158.25 0.00077585 14049000 3294.9 2942 4080 3048.4 3594 2832.4 3753.1 6617.4 2151.4 2296.9 TRUE FALSE FALSE 3034.105188 3196.293371 4231.208389 3035.786529 3551.143897 2244.928312 3858.401885 8635.014797 1915.396803 2376.717104 1.276595007 1.344835431 1.780274304 1.277302428 1.494138234 0.944550072 1.623416552 3.633168955 0.805900205 1 11.21475448 -4.272722828 3.234803581 1.221604123 3.945495861 0.876937313 0.267275501 0.074311258 1.23924783 0.036106934 0.498982268 5.34E-05 4.272722828 2.723891739 up EFHLNES(ph)GDPSSK ddPTM_HeLa_Curcumin_4h_R1 1 EFHLNESGDPSSK 13 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 1 0 EFHLNES(0.992)GDPS(0.007)S(0.001)K 102.03 0.0028357 8618800 3811.2 3606.7 3965.5 3675.9 4042 5304.9 3982 4079.5 4599.9 3655.1 TRUE FALSE FALSE 3509.539498 3918.447077 4112.464918 3660.6901 3993.80179 4204.603941 4093.724203 5323.32077 4095.302478 3782.114453 0.927930538 1.036046668 1.087345444 0.967895114 1.055970632 1.111707219 1.082390354 1.407498593 1.082807654 1 11.88497731 -1 0.59942915 0.978145935 26.1332679 0.747010783 0.062167816 45.31070666 0.323669644 0.009924214 1497.166925 0.1 1 25.15512196 EFHLNESGDPS(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 EFHLNESGDPSSK 13 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 1 0 EFHLNES(0.004)GDPS(0.498)S(0.498)K 127.3 0.0018336 7164400 1705.3 1533 1751.2 1389.4 1963.3 2402.8 1662.8 1825.7 2050.9 1728.2 TRUE FALSE FALSE 1570.323706 1665.505689 1816.101013 1383.651031 1939.88893 1904.432195 1709.453693 2382.347526 1825.921401 1788.254821 0.878131957 0.931358143 1.015571713 0.773743772 1.084794464 1.064966901 0.955934061 1.332219266 1.021063318 1 10.80433662 -1.119906972 0.948728716 0.943561836 199.9999939 0.572237972 0.0912912 463.6663911 0.998308491 0.013463694 200008.1438 0.075874008 1.119906972 199.056432 EFHLNESGDPSSK ddPTM_HeLa_Curcumin_4h_R1 3 EFHLNESGDPSSK 13 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 0 ;; ;; 145.52 0.00010711 70140000 24296.7 20091.7 19131.8 18466.9 26037.7 39821.9 25543.4 24666 27140.7 20718.3 FALSE FALSE TRUE 22373.59056 21828.33702 19840.84134 18390.48886 25727.21743 31562.38905 26260.07906 32186.54985 24163.43311 21438.25938 1.043629063 1.018195397 0.925487512 0.857834982 1.200060927 1.47224588 1.224916566 1.501360221 1.127117304 1 14.38790015 -5.527842941 5.256414337 1.002997392 1.377371934 0.780426876 0.096171454 0.053648086 4.598512983 0.01221857 0.025925551 2.97E-06 5.527842941 0.374374542 EFIPPNPWS(ph)SS(ph)GLS(ph)GKSS(ph)GTMSVISK ddPTM_HeLa_Curcumin_4h_R1 1 EFIPPNPWSSSGLSGKSSGTMSVISK 26 1 Q9UPZ9 Q9UPZ9 ICK Serine/threonine-protein kinase ICK 4 0 EFIPPNPWS(0.529)S(0.529)S(0.781)GLS(0.52)GKS(0.463)S(0.294)GT(0.294)MS(0.294)VIS(0.294)K 44.632 0.0072035 0 1539.1 974.37 1598.8 1559.4 1190.4 1198.7 1226.7 1170 1003.9 987.06 TRUE FALSE FALSE 1417.278611 1058.590201 1658.052934 1552.947616 1176.205257 950.0761079 1261.117901 1526.727614 893.7746816 1021.360262 1.387638294 1.03645133 1.623377173 1.52046998 1.151606638 0.930206651 1.234743457 1.494798331 0.875082687 1 9.996276118 -9.416145617 1.039299565 0.992820593 1.296484906 0.302535644 0.212305469 0.719860234 1.336518534 0.166794599 0.038281578 3.84E-10 9.416145617 0.303664313 EFIPPNPWS(ph)SSGLSGKS(ph)S(ph)GTMS(ph)VISK ddPTM_HeLa_Curcumin_4h_R1 1 EFIPPNPWSSSGLSGKSSGTMSVISK 26 1 Q9UPZ9 Q9UPZ9 ICK Serine/threonine-protein kinase ICK 4 0 EFIPPNPWS(0.476)S(0.476)S(0.049)GLS(0.457)GKS(0.513)S(0.513)GT(0.513)MS(0.501)VIS(0.501)K 61.89 0.0012519 11412000 1666.4 1411.9 1490.4 1746 1259.3 940.1 1433 1475.6 1180 1268.3 TRUE FALSE FALSE 1534.502682 1533.938345 1545.635535 1738.775515 1244.28367 745.1126629 1473.206123 1925.503647 1050.556952 1312.373331 1.169257745 1.168827733 1.177740738 1.324909211 0.948117156 0.567759681 1.122551098 1.467191997 0.800501601 1 10.35796247 EFITGDVEPTDAES(ph)EWHSENEEEEK ddPTM_HeLa_Curcumin_4h_R1 1 EFITGDVEPTDAESEWHSENEEEEK 25 0 C9J6D1;Q99733;Q99733-2;E9PNJ7;A8MXH2;E9PKT8;C9JZI7;E9PS34 C9J6D1 NAP1L4 Nucleosome assembly protein 1-like 4 1 0 EFITGDVEPT(0.145)DAES(0.852)EWHS(0.002)ENEEEEK 92.01 6.28E-06 5458100 2690.4 2583.3 2305.5 1978.8 3927.4 3923.6 3101.2 2726.2 3119.1 2349.5 TRUE FALSE FALSE 2477.452001 2806.588941 2390.943858 1970.61225 3880.56832 3109.801132 3188.211326 3557.40583 2776.942534 2431.14495 1.019047425 1.154430936 0.983464132 0.810569625 1.596189614 1.279150851 1.311403224 1.463263566 1.142236514 1 11.2474202 -5.761815365 24.99999892 1.006794642 1.395755416 0.71925694 0.120345052 3.647506985 242557.2425 0.015675469 0.029740974 1.73E-06 5.761815365 0.388960774 EFITGDVEPTDAES(ph)EWHSENEEEEKLAGDMK ddPTM_HeLa_Curcumin_4h_R1 1 EFITGDVEPTDAESEWHSENEEEEKLAGDMK 31 1 C9J6D1;Q99733;Q99733-2;E9PNJ7;A8MXH2;E9PKT8;C9JZI7 C9J6D1 NAP1L4 Nucleosome assembly protein 1-like 4 1 0 EFITGDVEPT(0.105)DAES(0.467)EWHS(0.427)ENEEEEKLAGDMK 57.688 0.00061458 188410000 4761.2 3590.9 3750 3793 4722.6 7356.8 4756.6 4636.3 5902 4365.5 TRUE FALSE FALSE 4384.345996 3901.281395 3888.978299 3777.305571 4666.286079 5830.916752 4890.057394 6049.886527 5254.565366 4517.2008 0.97058913 0.863650205 0.860926594 0.836204928 1.033003908 1.290825228 1.082541514 1.339299888 1.163234844 1 12.14121333 -5.41977623 4.752863784 0.955021454 1.219876967 0.5873016 0.107591533 0.106074676 3.829567801 0.012799511 0.029197151 3.80E-06 5.41977623 0.264855512 EFITGDVEPTDAESEWHS(ph)ENEEEEK ddPTM_HeLa_Curcumin_4h_R1 3 EFITGDVEPTDAESEWHSENEEEEK 25 0 C9J6D1;Q99733;Q99733-2;E9PNJ7;A8MXH2;E9PKT8;C9JZI7;E9PS34 C9J6D1 NAP1L4 Nucleosome assembly protein 1-like 4 1 0 EFITGDVEPTDAES(0.017)EWHS(0.983)ENEEEEK;EFITGDVEPT(0.003)DAES(0.081)EWHS(0.916)ENEEEEK;EFITGDVEPT(0.009)DAES(0.216)EWHS(0.775)ENEEEEK ;; 115.06 8.53E-09 389055000 9610.4 8688.7 7947.3 6710.2 13059.9 13078.5 9909.8 9614.1 9059.8 7895.3 TRUE FALSE FALSE 8849.726699 9439.712512 8241.833929 6682.43497 12904.16922 10365.87167 10187.84232 12545.39483 8065.962607 8169.661087 1.083242818 1.1554595 1.008834252 0.817957428 1.5795232 1.268825177 1.247033654 1.535607744 0.987306881 1 12.99606052 -5.759231198 24.99999998 1.033529543 1.386344858 0.701110719 0.12668716 26.74709229 302811.0159 0.017838208 0.034335984 1.74E-06 5.759231198 0.352815315 EFITGDVEPTDAESEWHS(ph)ENEEEEKLAGDMK ddPTM_HeLa_Curcumin_4h_R1 4 EFITGDVEPTDAESEWHSENEEEEKLAGDMK 31 1 C9J6D1;Q99733;Q99733-2;E9PNJ7;A8MXH2;E9PKT8;C9JZI7 C9J6D1 NAP1L4 Nucleosome assembly protein 1-like 4 1 0 EFITGDVEPT(0.003)DAES(0.03)EWHS(0.966)ENEEEEKLAGDMK;EFITGDVEPT(0.005)DAES(0.026)EWHS(0.969)ENEEEEKLAGDMK;EFITGDVEPT(0.001)DAES(0.049)EWHS(0.95)ENEEEEKLAGDMK;EFITGDVEPTDAES(0.003)EWHS(0.997)ENEEEEKLAGDMK ;;; 149.44 3.72E-13 1121533000 13734.1 11227 10308.3 9662.7 15791.4 21009.7 13595.3 14502.2 17078.6 12717.5 TRUE FALSE FALSE 12647.03149 12197.41185 10690.33467 9622.718308 15603.09787 16652.05139 13976.74753 18923.85402 15205.12031 13159.43218 0.961062098 0.926894997 0.812370513 0.731241149 1.185696895 1.265408048 1.062108709 1.438044876 1.155454134 1 13.68380962 -5.598350093 9.204539258 0.946979996 1.234173951 0.55210032 0.135538788 0.169221521 19.00748939 0.017414158 0.034869448 2.52E-06 5.598350093 0.287193955 EFLEDYDDDRDDPK ddPTM_HeLa_Curcumin_4h_R1 2 EFLEDYDDDRDDPK 14 1 P49756 P49756 RBM25 RNA-binding protein 25 0 0 ; ; 124.48 0.0012209 83152000 7794.4 7408.9 7686.9 8248.6 9649.7 8712.3 8222.8 7247.3 6380.5 6089 FALSE FALSE TRUE 7177.465015 8049.292303 7971.783276 8214.469479 9534.63363 6905.270772 8453.509637 9456.968408 5680.575113 6300.592297 1.139173061 1.277545336 1.265243472 1.303761471 1.513291637 1.095971688 1.341700786 1.500964983 0.901593826 1 12.62127174 -7.451890837 0.53108811 1.008971231 1.364949114 0.632371637 0.11534602 0.375443205 0.251990905 0.042714134 0.043069786 3.53E-08 7.451890837 0.355977883 EFLEDYDDDRDDPKYYR ddPTM_HeLa_Curcumin_4h_R1 2 EFLEDYDDDRDDPKYYR 17 2 P49756 P49756 RBM25 RNA-binding protein 25 0 0 ; ; 78.505 0.0039287 69812300 10143.1 7378.9 8396.3 8408 8401.6 10755.8 8352.9 8312.8 10757.1 8418 FALSE FALSE TRUE 9340.262932 8016.699236 8707.474264 8373.209924 8301.416407 8524.925837 8587.259893 10847.33445 9577.073043 8710.524873 1.072296224 0.920346288 0.999649779 0.961275014 0.953032857 0.978692554 0.985848731 1.245313527 1.099482888 1 13.08854394 -4.258046197 24.57624962 1.008514402 1.245313641 0.668311044 0.05194316 126.2312431 914216.6404 0.007393285 0.071614425 5.52E-05 4.258046197 0.236799239 EFNAEVHR ddPTM_HeLa_Curcumin_4h_R1 6 EFNAEVHR 8 0 P46777;A0A2R8Y6J3 P46777 RPL5 60S ribosomal protein L5 0 0 ;;;;; ;;;;; 168.26 0.0006092 66035100 29091.04 26713.08 27541.11 26766.1 31785.94 30823 25619.44 24034.28 24961.78 25152.5 FALSE FALSE TRUE 26788.45349 29022.0396 28561.80776 26655.34897 31406.91343 24429.96235 26338.25254 31362.22133 22223.53519 26026.5475 1.029274186 1.115093717 1.097410548 1.024160003 1.206726072 0.938655515 1.011976426 1.205008898 0.853879493 1 14.66769633 -7.453151781 4.615837658 1.012410239 1.079817696 0.222085413 0.09290211 0.321140637 12.47053864 0.013026147 0.014604455 3.52E-08 7.453151781 0.067407457 EFNAEVHRK ddPTM_HeLa_Curcumin_4h_R1 3 EFNAEVHRK 9 1 P46777;A0A2R8Y6J3 P46777 RPL5 60S ribosomal protein L5 0 0 ;; ;; 89.355 0.0020033 19251600 17680.4 14631.9 15171.5 15827.4 14577.2 19068.5 13124.9 14196 18166.9 16574.9 FALSE FALSE TRUE 16280.97768 15896.61624 15733.76914 15761.91041 14403.37641 15113.47815 13493.14937 18524.29505 16174.03652 17150.87654 0.949279627 0.926869026 0.917374054 0.919014861 0.839804098 0.881207332 0.786732348 1.080078619 0.943044309 1 14.06599469 -7.518562063 0.637932573 0.991630975 0.890647939 0.104467494 0.072674296 0.653013215 0.593348167 0.021621112 0.021230195 3.03E-08 7.518562063 -0.100983036 EFNK(ac)YDTDGSK ddPTM_HeLa_Curcumin_4h_R1 2 EFNKYDTDGSK 11 1 B4DXW1;P61158 B4DXW1 ACTR3 Actin-related protein 3 0 1 ; EFNK(1)YDTDGSK;EFNK(1)YDTDGSK 161.93 7.80E-08 4410200 2157.28 2369.99 1716.43 1932.14 2859.6 4155.9 3476 3059.2 3843.3 1925.24 FALSE TRUE FALSE 1986.529012 2574.841375 1780.042406 1924.145317 2825.501138 3293.919493 3573.527205 3991.935997 3421.699605 1992.141947 0.997182462 1.29249895 0.893531914 0.965867578 1.418323198 1.65345622 1.793811536 2.003841144 1.717598292 1 10.96010473 -5.308133293 1.395818101 1.009322925 1.924704528 0.561298583 0.252820951 0.090440285 0.32624866 0.017471556 0.066191024 4.92E-06 5.308133293 0.915381603 EFPTVPLVK ddPTM_HeLa_Curcumin_4h_R1 2 EFPTVPLVK 9 0 A0A087WYS1;E7EUC7;Q16851-2;Q16851 A0A087WYS1 UGP2 UTP--glucose-1-phosphate uridylyltransferase 0 0 ; ; 128.69 0.00069868 2292390 3602.1 2579.7 2519.58 3222.7 3073.98 4015.1 2794.6 2659.68 3641.8 3266.5 FALSE FALSE TRUE 3316.989984 2802.677773 2612.957851 3209.365321 3037.324796 3182.323 2873.008955 3470.604188 3242.303651 3380.010632 0.981354897 0.829191999 0.773062021 0.949513381 0.898613977 0.941512719 0.849999976 1.026802743 0.959258418 1 11.72281207 -7.391908423 7.159767282 0.99180144 0.89314764 0.246568972 0.067028726 0.219171268 11.84168328 0.011056947 0.01260315 4.06E-08 7.391908423 -0.0986538 EFSGGS(ph)YSAK ddPTM_HeLa_Curcumin_4h_R1 1 EFSGGSYSAK 10 0 H0Y7V8;A0A0A0MRJ1;H0Y5V1;A0A0A0MRJ0;Q5VT25-3;Q5VT25-4;Q5VT25-5;Q5VT25;Q5VT25-2;Q5VT25-6 H0Y7V8 CDC42BPA Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase MRCK alpha 1 0 EFS(0.102)GGS(0.891)YS(0.007)AK 112.83 0.0063867 32643000 2628.3 1478.1 2089.8 2257.3 1988.3 2156.2 1785.1 2371.4 2194.5 1975.7 TRUE FALSE FALSE 2420.267282 1605.860378 2167.249826 2247.959891 1964.590821 1708.979815 1835.185102 3094.428943 1953.76884 2044.355428 1.183877935 0.785509386 1.060114008 1.099593476 0.960983004 0.835950438 0.897683972 1.51364528 0.955689414 1 10.99743033 EFSGPS(ph)TPTGTLEFEGGEVSLEGGK ddPTM_HeLa_Curcumin_4h_R1 1 EFSGPSTPTGTLEFEGGEVSLEGGK 25 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 EFS(0.174)GPS(0.303)T(0.254)PT(0.254)GT(0.016)LEFEGGEVSLEGGK 84.602 4.63E-05 38988000 7772.1 6246.8 7222.5 7135.9 8203.3 9936.8 9722 9284.7 6890.1 6190.6 TRUE FALSE FALSE 7156.930084 6786.745557 7490.172204 7106.373537 8105.481005 7875.795669 9994.773155 12115.56229 6134.273268 6405.722889 1.11727126 1.059481603 1.169293823 1.109378857 1.265349929 1.229493658 1.560288094 1.891365346 0.957623889 1 12.64514567 -1 0.483485265 1.051901392 25.78573711 0.951905261 0.059435225 11.5530909 0.115602492 0.011217651 289.725063 0.1 1 24.73383572 ETEAAPT(ph)SPPIVPLK ddPTM_HeLa_Curcumin_4h_R1 1 ETEAAPTSPPIVPLK 15 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;Q7Z3B3-4;Q7Z3B3-2 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 0 ETEAAPT(0.749)S(0.251)PPIVPLK 186.51 4.71E-05 42764000 4556.8 3722.3 4147.9 4464.4 3622 4531.5 4591.2 6303 4538.5 3806.3 TRUE FALSE FALSE 4196.124472 4044.039026 4301.624823 4445.927496 3578.810016 3591.615819 4720.016715 8224.755685 4040.637905 3938.568642 1.065393257 1.026778861 1.092179727 1.128818081 0.90865752 0.911908906 1.198409154 2.088260085 1.025915319 1 11.9434557 -4.272569025 3.302858709 1.027681407 2.219888552 0.957089048 0.067486 0.043698938 0.776893245 0.009672596 0.130163597 5.34E-05 4.272569025 1.192207145 up EFSPFGSITSAK ddPTM_HeLa_Curcumin_4h_R1 2 EFSPFGSITSAK 12 0 H0Y5F5;B1ANR0;Q13310-2;Q13310;Q13310-3;H0YEU6 H0Y5F5 PABPC4 Polyadenylate-binding protein;Polyadenylate-binding protein 4 0 0 ; ; 195.27 3.50E-14 2021750 777.54 669.24 812.74 904.69 545.65 964.77 722.53 643.32 782.61 851.04 FALSE FALSE TRUE 715.9968885 727.0861235 842.8608594 900.9466325 539.1434801 764.6658268 742.8022472 839.4653065 696.759641 880.6135767 0.813065921 0.825658544 0.957129076 1.023089646 0.612236166 0.868332998 0.843505332 0.953273182 0.791220644 1 9.782365277 -9.404266935 1.068741499 1.002034933 0.856782988 0 0.122899025 0.685229919 1.368766225 0.076353146 0.018352123 3.94E-10 9.404266935 -0.145251945 EFSPFGTITSAK ddPTM_HeLa_Curcumin_4h_R1 1 EFSPFGTITSAK 12 0 P11940;P11940-2;E7EQV3;A0A087WTT1;E7ERJ7;H0YAR2;H0YAP2;H0YB86 P11940 PABPC1 Polyadenylate-binding protein 1;Polyadenylate-binding protein 0 0 175.65 2.58E-07 1678300 724.9 551 533.33 723.61 610.29 878.97 433.6 593.82 937.55 808.38 FALSE FALSE TRUE 667.5234001 598.6259848 553.095679 720.6158936 603.0126903 696.661714 445.765649 774.8729844 834.7031106 836.4711448 0.798023224 0.715656468 0.661225055 0.861495221 0.720900768 0.832858035 0.532912165 0.926359492 0.997886318 1 9.708171963 -8.695114045 0.631032027 1.004638938 0.743261954 0.457416152 0.105138801 0.503759862 0.387525639 0.066312217 0.023244992 2.02E-09 8.695114045 -0.261376984 EFT(ph)ESQLQEGK ddPTM_HeLa_Curcumin_4h_R1 2 EFTESQLQEGK 11 0 Q01995;H0YCU9 Q01995 TAGLN Transgelin 1 0 EFT(0.826)ES(0.174)QLQEGK;EFT(0.995)ES(0.005)QLQEGK ; 166.45 6.00E-05 5077100 4685.4 4311 4564.63 4660.9 4795.3 5686.8 4442.1 4597.9 4838.7 4170.25 TRUE FALSE FALSE 4314.545646 4683.623631 4733.799203 4641.614431 4738.119179 4507.293577 4566.733371 5999.778544 4307.906716 4315.165877 0.999856267 1.085386695 1.097014423 1.07565145 1.098015537 1.044523827 1.058298453 1.39039349 0.998317756 1 12.0752003 EFTEAVEAK ddPTM_HeLa_Curcumin_4h_R1 2 EFTEAVEAK 9 0 P35232;C9JZ20;E7ESE2;E9PCW0;C9JW96 P35232 PHB Prohibitin 0 0 ; ; 118.26 0.001485 7826800 6843.2 5161.9 6093.7 6533.2 5176.4 6551.7 4908.7 4621.2 6533.6 5261.7 FALSE FALSE TRUE 6301.553499 5608.071635 6319.537883 6506.167349 5114.674811 5192.803567 5046.424911 6030.182607 5816.880426 5444.543683 1.157407097 1.030035199 1.160710291 1.194988548 0.939412944 0.953762862 0.926877477 1.107564372 1.068387135 1 12.41059542 -5.734995739 24.99993144 1.087109932 0.975963785 0.376866706 0.073993094 227.1327807 214731.1185 0.012340635 0.024675431 1.84E-06 5.734995739 -0.111146147 EFTES(ph)QLQEGK ddPTM_HeLa_Curcumin_4h_R1 2 EFTESQLQEGK 11 0 Q01995;H0YCU9 Q01995 TAGLN Transgelin 1 0 EFT(0.298)ES(0.702)QLQEGK;EFT(0.008)ES(0.992)QLQEGK ; 122.97 0.002443 11949000 6596.8 5112.5 6572 7102.4 7246.4 6948.6 6337.2 5710.2 6160.9 5633.7 TRUE FALSE FALSE 6074.656319 5554.401719 6815.564101 7073.012151 7159.991413 5507.382033 6515.004776 7451.213693 5485.064684 5829.470656 1.042059679 0.95281408 1.169156602 1.213319797 1.228240407 0.944748221 1.117598005 1.278197307 0.940919855 1 12.50914917 -6.749313636 24.99884007 1.015387911 1.152622177 0.462166388 0.089605947 183.5390708 378389.5301 0.013716642 0.019314118 1.78E-07 6.749313636 0.137234266 EFTESQLQEGK ddPTM_HeLa_Curcumin_4h_R1 3 EFTESQLQEGK 11 0 Q01995;H0YCU9 Q01995 TAGLN Transgelin 0 0 ;; ;; 265.01 1.31E-79 26969000 7405 5781.2 6107 6612.6 6636.4 8083.6 6484.3 5978.9 7269.8 6076.2 FALSE FALSE TRUE 6818.886436 6280.901167 6333.330792 6585.238813 6557.265264 6406.970239 6666.232006 7801.839087 6472.321128 6287.347498 1.084541047 0.998974714 1.007313624 1.04737949 1.042930308 1.019025947 1.060261423 1.240879256 1.029419979 1 12.61823579 -4.264213299 3.588090188 1.035128214 1.263981363 0.863553151 0.025054237 0.098594449 2.265367233 0.004675587 0.060216714 5.44E-05 4.264213299 0.228853149 EFTGS(ph)PPSSATK ddPTM_HeLa_Curcumin_4h_R1 2 EFTGSPPSSATK 12 0 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 0 EFT(0.002)GS(0.965)PPS(0.017)S(0.017)ATK;EFT(0.077)GS(0.834)PPS(0.075)S(0.015)ATK ; 115.24 0.0040522 60459000 7167.7 6172.5 6983.3 6888.4 6990.6 7971.1 6093.1 5333.3 7275 6593.3 TRUE FALSE FALSE 6600.368982 6706.023396 7242.107241 6859.897626 6907.241661 6317.804007 6264.055987 6959.398619 6476.950701 6822.416684 0.967453219 0.982939581 1.061516406 1.005493793 1.012433274 0.926036081 0.918157931 1.020078213 0.949363107 1 12.73606716 -5.266349296 24.9902783 0.993293402 0.95109746 0.200748202 0.037935154 462.2677689 2352840.702 0.005219018 0.012039805 5.42E-06 5.266349296 -0.042195941 EFTGS(ph)PPSSATKK ddPTM_HeLa_Curcumin_4h_R1 1 EFTGSPPSSATKK 13 1 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 0 EFT(0.035)GS(0.965)PPSSATKK 92.773 0.0050378 285000000 8863 7672.2 7598.7 7335.7 7881.7 9397.2 6755.3 6532.7 9165.3 7953.9 TRUE FALSE FALSE 8161.484198 8335.350781 7880.314506 7305.346817 7787.715875 7448.114792 6944.835537 8524.490157 8159.88952 8230.297433 0.991639034 1.012764223 0.957476272 0.88761638 0.946225326 0.904963017 0.843813434 1.03574509 0.991445277 1 13.00672885 -6.534514947 4.778916991 0.996974331 0.919438963 0.366521482 0.046405892 0.136001287 8.305633155 0.00658386 0.009644333 2.92E-07 6.534514947 -0.077535368 EFVISDRK ddPTM_HeLa_Curcumin_4h_R1 2 EFVISDRK 8 1 H3BT58;Q14019 H3BT58 COTL1 Coactosin-like protein 0 0 ; ; 82.241 0.011159 7255500 4938 3677.4 3706.9 4180 3898.6 5196.7 4202.2 3664.7 4330 4436.9 FALSE FALSE TRUE 4547.152089 3995.25807 3844.280975 4162.704268 3852.111741 4118.845841 4320.102422 4782.05016 3855.009833 4591.081945 0.990431481 0.870221468 0.837336606 0.906693524 0.839042254 0.897140563 0.94097698 1.041595471 0.839673497 1 12.16461847 -7.278478103 20.15303308 0.995481606 0.900777349 0 0.073882124 49.8234981 58929.72095 0.009586655 0.010992801 5.27E-08 7.278478103 -0.094704257 EGAAGS(ph)PGGPR ddPTM_HeLa_Curcumin_4h_R1 2 EGAAGSPGGPR 11 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6;H7BZZ8;B5MCI0;P53814-2 A0A087WVP4 SMTN Smoothelin 1 0 EGAAGS(1)PGGPR;EGAAGS(1)PGGPR ; 114.76 0.0049572 49712000 12225.1 20822.6 13914.9 16565.1 10942.1 15753.9 15327.9 9111.2 22593.6 20938.9 TRUE FALSE FALSE 11257.47044 22622.41276 14430.59843 16496.55801 10811.6226 12486.36356 15757.95962 11889.16294 20115.13861 21666.52522 0.519578951 1.044118175 0.666031968 0.761384571 0.499001224 0.576297465 0.727295192 0.548734179 0.928397074 1 14.40318018 -9.500165037 1.129729527 1.008542046 0.659589705 0.375425881 0.15202752 0.421319796 0.923016974 0.120481672 0.026393934 3.16E-10 9.500165037 -0.348952341 EGAASPAPETPQPT(ph)S(ph)PETSPK ddPTM_HeLa_Curcumin_4h_R1 1 EGAASPAPETPQPTSPETSPK 21 0 A0A2R8Y4Z8;Q9Y3X0 A0A2R8Y4Z8;Q9Y3X0 CCDC9 Coiled-coil domain-containing protein 9 2 0 EGAASPAPET(0.005)PQPT(0.9)S(0.584)PET(0.421)S(0.09)PK 73.918 0.002526 0 1471.3 1327.1 1409.8 1706.2 1614.1 1792.9 1358.7 1677.2 1505.6 1637.8 TRUE FALSE FALSE 1354.845052 1441.808611 1462.048428 1699.140196 1594.852912 1421.03233 1396.821465 2188.570559 1340.439447 1694.713428 0.799453778 0.850768388 0.862711302 1.002612104 0.941075279 0.838508922 0.824222811 1.291410408 0.790953458 1 10.72682562 -6.266591595 24.01045549 0.895031262 0.960960864 0.133918875 0.133794022 667.7943402 3112073.231 0.020966653 0.032658348 5.41E-07 6.266591595 0.065929603 EGAKDIDIS(ph)SPEFK ddPTM_HeLa_Curcumin_4h_R1 1 EGAKDIDISSPEFK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 EGAKDIDIS(0.848)S(0.152)PEFK 94.639 0.003345 19249000 3642.8 3153.3 2538.2 3414.3 1702.2 4586.6 2884.7 2194.5 6822.8 3997.4 TRUE FALSE FALSE 3354.468536 3425.857201 2632.267925 3400.172531 1681.902377 3635.287458 2965.636918 2863.592948 6074.35591 4136.309352 0.810981058 0.828240083 0.636380817 0.822030521 0.406619098 0.878872238 0.716976576 0.692306282 1.468544877 1 12.01412837 -8.126661534 0.485047701 1.00374055 0.687450935 0.441851503 0.195929069 0.577403119 0.317311477 0.076770744 0.041011495 7.47E-09 8.126661534 -0.316289616 EGAKDIDISS(ph)PEFK ddPTM_HeLa_Curcumin_4h_R1 2 EGAKDIDISSPEFK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 EGAKDIDIS(0.053)S(0.947)PEFK;EGAKDIDIS(0.032)S(0.968)PEFK ; 146.59 0.00046496 400004000 15606.9 10574.4 9888.4 12705.7 6181.7 16434.4 10068 8186.6 22941 14321.2 TRUE FALSE FALSE 14371.5974 11488.40402 10254.8728 12653.12718 6107.987265 13025.72019 10350.48098 10682.65665 20424.4297 14818.86063 0.969817974 0.775255554 0.69201493 0.853852904 0.412176578 0.878996065 0.69846672 0.720882456 1.378272608 1 13.85514691 -7.191909135 2.620061038 0.988326191 0.709408069 0.495712242 0.170610147 0.147244261 1.949210632 0.018946364 0.02304777 6.43E-08 7.191909135 -0.278918121 EGALCEENMR ddPTM_HeLa_Curcumin_4h_R1 2 EGALCEENMR 10 0 P13639 P13639 EEF2 Elongation factor 2 0 0 ; ; 162.88 2.77E-09 21499600 4699.2 3960.8 3848.7 3892.4 4498.3 5146.5 3873.9 3486 4626.5 4023.9 FALSE FALSE TRUE 4327.253361 4303.153903 3991.336208 3876.29428 4444.66071 4079.057887 3982.591208 4548.865352 4118.984525 4163.730225 1.03927323 1.033485281 0.958596257 0.930966722 1.067470866 0.979664307 0.956495977 1.092497618 0.989253458 1 12.02366088 EGDELEDNGKNFYES(ph)DDDQKEK ddPTM_HeLa_Curcumin_4h_R1 2 EGDELEDNGKNFYESDDDQKEK 22 2 O00203-3;O00203 O00203-3 AP3B1 AP-3 complex subunit beta-1 1 0 EGDELEDNGKNFY(0.364)ES(0.636)DDDQKEK;EGDELEDNGKNFY(0.463)ES(0.537)DDDQKEK ; 81.888 0.00055287 300279000 6833 6360.5 7775.2 7625.8 7999.3 6514.1 5900 5416.11 7181.28 6778 TRUE FALSE FALSE 6292.16084 6910.273278 8063.355752 7594.24646 7903.913572 5163.002231 6065.538121 7067.457006 6393.511551 7013.534995 0.897145426 0.985276794 1.149684967 1.082798684 1.12695147 0.736148352 0.86483323 1.007688279 0.911596157 1 12.77592607 -3.907801146 19.36309584 0.966759353 3.507089076 0.005343177 0.1206216 1917.191115 434188.2928 0.016977697 16740.24457 0.000123651 3.907801146 2.540329722 EGDGVYYNELETR ddPTM_HeLa_Curcumin_4h_R1 2 EGDGVYYNELETR 13 0 Q8N7H5-2;Q8N7H5-3;Q8N7H5 Q8N7H5-2 PAF1 RNA polymerase II-associated factor 1 homolog 0 0 ; ; 170.4 0.0016705 18256100 2274.04 1842.37 1998.68 2075.57 1852.97 2591.54 1953.38 1526.42 2428.5 1851.55 FALSE FALSE TRUE 2094.047334 2001.616253 2072.752839 2066.981841 1830.874543 2054.025391 2008.186586 1991.818431 2162.099626 1915.891225 1.092988635 1.044744204 1.081873967 1.078861793 0.955625517 1.07209917 1.048173591 1.039630228 1.128508549 1 10.90379994 EGDIIPPLTGAT(ph)PPLIGHLK ddPTM_HeLa_Curcumin_4h_R1 1 EGDIIPPLTGATPPLIGHLK 20 0 A6NNK5;Q12888;Q12888-3;Q12888-2;H7C3N7 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 EGDIIPPLTGAT(1)PPLIGHLK 140.45 0.00011275 78764000 3509 3149.3 2975.3 3294 3625.4 4588.6 3600.4 1884.3 3489.3 3013.3 TRUE FALSE FALSE 3231.258947 3421.511459 3085.567235 3280.370301 3582.169473 3636.872636 3701.417534 2458.814396 3106.53252 3118.011951 1.036320257 1.097337506 0.989594422 1.052071112 1.148863292 1.166407536 1.187108193 0.788584019 0.996318349 1 11.60641074 -5.995766452 24.7802338 1.022903552 1.08920871 0.034860781 0.108415454 228.2914094 1336236.89 0.014978701 0.027064105 1.01E-06 5.995766452 0.066305158 EGDLIAAQAR ddPTM_HeLa_Curcumin_4h_R1 2 EGDLIAAQAR 10 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 125.82 0.002062 19887400 7215.6 5939.2 6183.9 6057.1 6340.8 8475 5415.9 4838.7 7598.1 6105 FALSE FALSE TRUE 6644.477646 6452.557983 6413.080774 6032.037325 6265.190101 6717.189467 5567.855578 6313.997355 6764.60744 6317.148296 1.051815999 1.021435256 1.015186042 0.95486714 0.991775055 1.063326228 0.881387505 0.999501208 1.070832458 1 12.62505772 -6.420130306 5.633748586 1.024650093 0.978402909 0.248019374 0.046151728 0.290034708 13.20225946 0.006794828 0.010407809 3.80E-07 6.420130306 -0.046247184 EGDNVNYDWIHWDPEHSYEFK ddPTM_HeLa_Curcumin_4h_R1 2 EGDNVNYDWIHWDPEHSYEFK 21 0 E9PGM4;Q04446 E9PGM4 GBE1 "1,4-alpha-glucan-branching enzyme" 0 0 ; ; 161.14 2.12E-07 49295000 9480.6 7964.8 9287.2 8812.7 9195.4 10218.4 7592.4 7145.4 10164.5 9337.5 FALSE FALSE TRUE 8730.200506 8653.241822 9631.391802 8776.235382 9085.750861 8098.988655 7805.42231 9323.999567 9049.47978 9661.97743 0.903562503 0.895597395 0.996834434 0.908327042 0.940361425 0.838233034 0.807849363 0.965019804 0.936607423 1 13.23810277 -13.52287875 0.151858624 1.363277114 0.869028545 0.14948074 0.05477838 56.58530592 0.583512134 6.144134443 0.117878969 3.00E-14 13.52287875 -0.494248569 EGDPVSLSTPLETEFGS(ph)PSELS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 EGDPVSLSTPLETEFGSPSELSPR 24 0 Q9BUR4;E9PMG4;E9PMR3 Q9BUR4 WRAP53 Telomerase Cajal body protein 1 2 0 EGDPVSLSTPLET(0.001)EFGS(0.985)PS(0.029)ELS(0.985)PR;EGDPVSLSTPLETEFGS(0.984)PS(0.126)ELS(0.89)PR ; 154.27 3.08E-07 22043300 4582.1 3983 4059.3 4020.5 3637.7 5085.3 3558.7 3168.6 4363.5 4009 TRUE FALSE FALSE 4219.42195 4327.272772 4209.741229 4003.864236 3594.322803 4030.551457 3658.547544 4134.691554 3884.834967 4148.312452 1.017141789 1.043140511 1.014808137 0.965179042 0.866454214 0.971612313 0.88193635 0.996716521 0.936485622 1 12.01830885 -6.066851462 4.354764797 1.011639446 0.927408607 0.367417987 0.044151007 0.118551444 4.389431555 0.005076948 0.00873707 8.57E-07 6.066851462 -0.084230839 EGDPVSLSTPLETEFGS(ph)PSELSPR ddPTM_HeLa_Curcumin_4h_R1 2 EGDPVSLSTPLETEFGSPSELSPR 24 0 Q9BUR4;E9PMG4;E9PMR3 Q9BUR4 WRAP53 Telomerase Cajal body protein 1 1 0 EGDPVSLSTPLETEFGS(0.98)PS(0.02)ELSPR;EGDPVSLSTPLET(0.021)EFGS(0.875)PS(0.103)ELS(0.001)PR ; 196.7 9.14E-15 20297500 6846.5 5019.8 5258.1 6004.7 5711.7 7319.9 5418 4613.2 6130 5199.4 TRUE FALSE FALSE 6304.592301 5453.689144 5452.969811 5979.854142 5643.591708 5801.670228 5570.014498 6019.743443 5457.554337 5380.078763 1.171840149 1.013682027 1.013548324 1.11148078 1.048979384 1.078361579 1.035303523 1.11889504 1.014400453 1 12.39341158 -9.765188956 1.732444309 0.999927673 1.087974559 0.187377611 0.049105637 0.427312401 2.320824516 0.04188251 0.008946733 1.72E-10 9.765188956 0.088046886 EGDPVSLSTPLETEFGSPS(ph)ELSPR ddPTM_HeLa_Curcumin_4h_R1 1 EGDPVSLSTPLETEFGSPSELSPR 24 0 Q9BUR4;E9PMG4;E9PMR3 Q9BUR4 WRAP53 Telomerase Cajal body protein 1 1 0 EGDPVSLSTPLETEFGS(0.012)PS(0.833)ELS(0.156)PR 159.38 3.27E-08 28181000 2836.9 2626.6 2470 2267.5 2286 3140.8 2499.5 2850.7 2703.3 2591.5 TRUE FALSE FALSE 2612.356372 2853.6316 2561.540373 2258.117686 2258.740943 2489.362676 2569.629243 3719.865307 2406.754753 2681.554432 0.974194795 1.064170679 0.955244593 0.842092802 0.842325226 0.928328229 0.958261079 1.387204847 0.897522245 1 11.38885382 -4.260821787 24.63960952 0.965648924 1.387204999 0.785077956 0.069015451 15.6808175 625426.4741 0.010127338 0.080451816 5.49E-05 4.260821787 0.421556075 EGDPVSLSTPLETEFGSPSELS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 EGDPVSLSTPLETEFGSPSELSPR 24 0 Q9BUR4;E9PMG4;E9PMR3 Q9BUR4 WRAP53 Telomerase Cajal body protein 1 1 0 EGDPVSLSTPLETEFGSPS(0.17)ELS(0.829)PR;EGDPVSLSTPLETEFGSPS(0.122)ELS(0.878)PR;EGDPVSLSTPLETEFGSPS(0.025)ELS(0.975)PR ;; 238.1 4.30E-39 42049600 12613.9 10575.2 10359.2 11230.1 10552.8 13869.3 10098.5 12447.5 13354.5 11202.1 TRUE FALSE FALSE 11615.4965 11489.27317 10743.12106 11183.63282 10426.96475 10992.65084 10381.83673 16242.68545 11889.54476 11591.37214 1.002081235 0.991191813 0.926820478 0.964823895 0.899545336 0.948347677 0.895652094 1.401273745 1.025723669 1 13.50076374 -4.254626215 24.91962142 0.977455587 1.401273948 0.895847311 0.044683042 188.4855793 689380.4612 0.006675972 0.086938534 5.56E-05 4.254626215 0.423818361 EGDVLTLLES(ph)ER ddPTM_HeLa_Curcumin_4h_R1 1 EGDVLTLLESER 12 0 P62857 P62857 RPS28 40S ribosomal protein S28 1 0 EGDVLT(0.001)LLES(0.999)ER 93.649 0.012852 1482700 841.19 802.91 805.79 859.34 821.41 1002 656.92 813.39 806.61 754.25 TRUE FALSE FALSE 774.6089239 872.3099627 835.6532862 855.7842788 811.6152222 794.1739051 675.3514072 1061.388867 718.126901 780.4601314 0.992502875 1.117686769 1.070718737 1.096512486 1.039918876 1.017571396 0.865324672 1.359952705 0.920132717 1 9.608181126 -4.245490934 24.987869 1.013844315 1.359952967 0.670881058 0.072823648 1316.92944 2063320.276 0.009324036 0.319753049 5.68E-05 4.245490934 0.346108652 EGDVLTLLES(ph)EREAR ddPTM_HeLa_Curcumin_4h_R1 1 EGDVLTLLESEREAR 15 1 P62857 P62857 RPS28 40S ribosomal protein S28 1 0 EGDVLTLLES(1)EREAR 114.03 0.00078893 5064000 2051.3 1748.2 1951.4 2017.7 1987.5 2081 1901.3 1470.2 2287.5 1835 TRUE FALSE FALSE 1888.93744 1899.306618 2023.720601 2009.351292 1963.800361 1649.377142 1954.645361 1918.457212 2036.566973 1898.766113 0.994823653 1.000284661 1.065808256 1.058240548 1.034250794 0.868657351 1.029429242 1.010370471 1.072573899 1 10.89084649 EGDVLTLLESER ddPTM_HeLa_Curcumin_4h_R1 4 EGDVLTLLESER 12 0 P62857 P62857 RPS28 40S ribosomal protein S28 0 0 ;;; ;;; 238.86 2.50E-25 123543000 9725.7 7969.61 9534.2 9425 9625.3 10738.3 9263.8 8179.5 10373.5 9111.5 FALSE FALSE TRUE 8955.900582 8658.467577 9887.545839 9386.001847 9510.524584 8511.055534 9523.717296 10673.3919 9235.553003 9428.123947 0.949913327 0.918365905 1.048728877 0.995532293 1.008739876 0.902730552 1.01013917 1.132080142 0.97957484 1 13.20275501 -4.305833452 3.772761163 0.976163264 1.141709609 0.563868862 0.041123731 0.126162339 3.274819443 0.005701986 0.052937485 4.95E-05 4.305833452 0.165546346 EGDYVLFHHEGGVDVGDVDAK ddPTM_HeLa_Curcumin_4h_R1 2 EGDYVLFHHEGGVDVGDVDAK 21 0 P53396;P53396-2 P53396 ACLY ATP-citrate synthase 0 0 ; ; 167.93 1.53E-08 65411300 9398.8 8372.6 8103.9 8539 7726.4 10577.2 8489.2 7830.6 10240.2 8728.5 FALSE FALSE TRUE 8654.875062 9096.290236 8404.237663 8503.667881 7634.267726 8383.36949 8727.384104 10218.11389 9116.87568 9031.814725 0.958265346 1.007138711 0.930514843 0.941523729 0.845263987 0.928204325 0.966293527 1.131346712 1.009417925 1 13.14080018 -9.022148746 0.640503078 1.002528199 0.956850306 0.047037778 0.068793138 2.585744918 1.787327029 0.064417375 0.015860283 9.50E-10 9.022148746 -0.045677893 EGEEPTVYS(ph)DEEEPKDESAR ddPTM_HeLa_Curcumin_4h_R1 4 EGEEPTVYSDEEEPKDESAR 20 1 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 0 EGEEPTVYS(1)DEEEPKDESAR;EGEEPTVYS(1)DEEEPKDESAR;EGEEPTVYS(1)DEEEPKDESAR;EGEEPTVYS(0.999)DEEEPKDESAR ;;; 181.83 5.10E-08 1022741000 9804.1 10253.8 10480.3 13826.4 11433.8 16923.9 8266.4 5517.5 13918.7 11481.8 TRUE FALSE FALSE 9028.09514 11140.09278 10868.70914 13769.19002 11297.4594 13413.69237 8498.332936 7199.760351 12391.85343 11880.7917 0.759890028 0.937655761 0.914813542 1.158945496 0.950901227 1.129023445 0.715300222 0.606000049 1.043015798 1 13.53634336 -4.56762658 9.110913937 0.927043284 0.632954554 0.506908774 0.11952362 0.198317487 38.02552431 0.018875252 0.0712342 2.71E-05 4.56762658 -0.294088731 EGEETEGS(ph)EEDDKENDKTEEMPNDSVLENK ddPTM_HeLa_Curcumin_4h_R1 1 EGEETEGSEEDDKENDKTEEMPNDSVLENK 30 2 P49321-4;P49321;P49321-3 P49321-4 NASP Nuclear autoantigenic sperm protein 1 0 EGEET(0.276)EGS(0.686)EEDDKENDKT(0.036)EEMPNDS(0.002)VLENK 46.696 0.0066966 19632000 1998.1 1902.1 2123.1 1960.6 2154.4 2125.8 1858.2 2232 1487.6 1616.5 TRUE FALSE FALSE 1839.948277 2066.509048 2201.783954 1952.487557 2128.710187 1684.885117 1910.336091 2912.526525 1324.414002 1672.673255 1.100004601 1.235452915 1.316326394 1.167285691 1.272639579 1.007300806 1.142085632 1.741240566 0.79179481 1 10.70793994 -4.263733297 4.915707073 1.102475553 1.773354452 0.624226666 0.145850115 0.072899697 5.273408574 0.017595348 0.165792574 5.45E-05 4.263733297 0.670878899 EGEETLR ddPTM_HeLa_Curcumin_4h_R1 1 EGEETLR 7 0 A0A087X297;Q16719-2;Q16719;A0A087WYM2;A0A087WYQ7 A0A087X297 KYNU Kynureninase 0 0 111.65 0.012814 627700 923.24 901.69 879.11 946.46 863.13 1075 917.55 627.04 675.32 640.3 FALSE FALSE TRUE 850.1645798 979.6280657 911.6905899 942.5437993 852.8377385 852.0328823 943.2939835 818.2216095 601.2390856 662.5503773 1.283169716 1.47857144 1.376032104 1.422599445 1.287204366 1.285989581 1.423731713 1.234957578 0.907461691 1 9.371886345 -8.633682645 0.751760959 1.011748078 1.357232434 0.77428472 0.083372337 0.223662042 0.253890181 0.039804368 0.016971948 2.32E-09 8.633682645 0.345484356 EGEFVAQFK ddPTM_HeLa_Curcumin_4h_R1 2 EGEFVAQFK 9 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 0 ; ; 130.75 0.00057954 5818800 5017.8 4589.4 4250.5 4972 5075.2 5025.7 4530.6 4420.3 4548.5 4538.7 FALSE FALSE TRUE 4620.635835 4986.087286 4408.027269 4951.427181 5014.681555 3983.313169 4657.716443 5768.029121 4049.54093 4696.419487 0.983863526 1.061678434 0.938593173 1.054298321 1.067766959 0.848159578 0.991759032 1.228175877 0.862261334 1 12.19734556 -4.261273495 22.69114961 0.9927801 1.228176113 0.495679962 0.074278963 1.933916876 263599.6753 0.007896085 0.061186749 5.48E-05 4.261273495 0.235396014 EGETQGVAFEHESPADFQNS(ph)QSPVQDQDK ddPTM_HeLa_Curcumin_4h_R1 1 EGETQGVAFEHESPADFQNSQSPVQDQDK 29 0 E9PGM9;P78332;F8WCA5;P78332-3 E9PGM9 RBM6 RNA-binding protein 6 1 0 EGETQGVAFEHESPADFQNS(0.5)QS(0.5)PVQDQDK 110.78 7.57E-11 7501000 586.39 554.13 750.92 709.88 927.38 1860 657.33 564.25 975.53 623.56 TRUE FALSE FALSE 539.9766127 602.026528 778.7497558 706.9427047 916.3215992 1474.215033 675.7729107 736.2872275 868.5167997 645.2286636 0.836876356 0.933043682 1.206936083 1.095646775 1.420150175 2.284794704 1.047338639 1.141126036 1.346060472 1 9.33366672 -6.121268808 1.603134566 0.928455373 1.488530771 0.201486345 0.348121893 0.304790626 1.539609283 0.052074521 0.101594143 7.56E-07 6.121268808 0.560075398 EGFEK(ac)ISK ddPTM_HeLa_Curcumin_4h_R1 2 EGFEKISK 8 1 P10809;E7EXB4;E7ESH4;P10809-2;C9JL25 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 1 ; EGFEK(1)ISK;EGFEK(1)ISK 99.815 0.013347 24957000 9031.1 7176.8 7087.1 9202.7 8978.3 12871.9 8322.2 9032 10164.4 7547.1 FALSE TRUE FALSE 8316.278905 7797.130613 7349.75416 9164.621666 8871.239636 10202.12284 8555.698534 11785.81522 9049.39075 7809.361163 1.064911551 0.99843386 0.941146658 1.173543069 1.135975075 1.306396596 1.095569581 1.509190698 1.158787583 1 12.93098882 -1 0.396974038 1.018746383 7.74571311 0.608475421 0.099379923 25.3452533 0.300685713 0.020659539 134.5177072 0.1 1 6.726966727 EGFES(ph)DTDSEFTFK ddPTM_HeLa_Curcumin_4h_R1 1 EGFESDTDSEFTFK 14 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;E9PMP7 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 EGFES(1)DTDSEFTFK 205.27 4.26E-09 60451000 5147.4 3740.4 4224.9 4835 5533.1 5426.2 3988.8 1961.4 4227.3 3695.1 TRUE FALSE FALSE 4739.977858 4063.703509 4381.478511 4814.994051 5467.121396 4300.744954 4100.714993 2559.421831 3763.575766 3823.50445 1.23969461 1.062821703 1.14593263 1.259314358 1.429871854 1.124817562 1.072501692 0.669391618 0.984326242 1 11.90067984 -4.24848288 2.800589015 1.147331597 0.572920592 0.573141774 0.125225137 0.284306695 2.955434188 0.01926019 0.377827337 5.64E-05 4.24848288 -0.574411004 EGFESDT(ph)DSEFTFK ddPTM_HeLa_Curcumin_4h_R1 1 EGFESDTDSEFTFK 14 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;E9PMP7 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 EGFES(0.249)DT(0.69)DS(0.06)EFT(0.001)FK 180.85 0.00034671 31492000 3891 3201.9 3719.6 3302.8 4187.7 4192.8 3797.4 1437.2 3213.8 2838 TRUE FALSE FALSE 3583.023244 3478.657969 3857.451648 3289.133889 4137.764413 3323.166017 3903.944824 1875.395664 2861.254181 2936.620289 1.22011799 1.184578742 1.313568412 1.120040579 1.40902262 1.131629455 1.329400617 0.638623819 0.974335767 1 11.51994102 -2.840221156 13.53175625 1.137983824 1.159120204 0 0.21104323 0 0 0.025679103 0 0.001444704 2.840221156 0.02113638 EGFGLSENPFAS(ph)LSPDEQKDEK ddPTM_HeLa_Curcumin_4h_R1 1 EGFGLSENPFASLSPDEQKDEK 22 1 B4DT96;C9JYA1;O15504-2;O15504 B4DT96 NUPL2 Nucleoporin-like protein 2 1 0 EGFGLSENPFAS(0.5)LS(0.5)PDEQKDEK 136.71 1.14E-05 24267000 1955.3 1288.2 1852.1 1403.2 1539.2 2301 1770.4 1426.4 1400.3 1623.2 TRUE FALSE FALSE 1800.535942 1399.546268 1920.740455 1397.39393 1520.846045 1823.746662 1820.072659 1861.302794 1246.690593 1679.606079 1.071998943 0.833258634 1.14356603 0.831977181 0.905477817 1.085818089 1.083630669 1.108178171 0.742251775 1 10.7139072 -5.04235096 24.73943297 1.004424392 1.093109513 0.098483546 0.12721001 596.7145481 348572.1945 0.013643612 0.034788421 9.07E-06 5.04235096 0.088685121 EGFGLSENPFASLS(ph)PDEQKDEK ddPTM_HeLa_Curcumin_4h_R1 1 EGFGLSENPFASLSPDEQKDEK 22 1 B4DT96;C9JYA1;O15504-2;O15504 B4DT96 NUPL2 Nucleoporin-like protein 2 1 0 EGFGLSENPFAS(0.001)LS(0.999)PDEQKDEK 135.17 1.03E-05 23965000 2364.9 1999 1949.3 1956.6 2048.8 3241.9 2571.3 2341.1 2565.5 1968.5 TRUE FALSE FALSE 2177.71567 2171.784653 2021.542773 1948.504108 2024.369398 2569.493396 2643.443758 3054.890613 2284.071069 2036.905228 1.069129599 1.06621782 0.992457943 0.956600278 0.993845649 1.261469292 1.297774546 1.499770618 1.12134381 1 10.99216314 -4.838806177 1.545395556 1.024574475 1.472253508 0.864483419 0.060964901 0.110458006 0.44977328 0.008258748 0.053879498 1.45E-05 4.838806177 0.447679032 EGFLDTLVVLHR ddPTM_HeLa_Curcumin_4h_R1 1 EGFLDTLVVLHR 12 0 J3QRG6;P42771;P42771-4;K7ES20;K7ENC6;P42771-2;P42772 J3QRG6 CDKN2A;CDKN2B Cyclin-dependent kinase inhibitor 2A;Cyclin-dependent kinase 4 inhibitor B 0 0 158.05 4.83E-06 665650 332.1 253.6 217.01 174.72 270.6 405.45 199.13 258.31 268.61 138.52 FALSE FALSE TRUE 305.8139346 275.520054 225.0525815 173.9970549 267.3732717 321.3550996 204.7170519 337.0675299 239.144155 143.3335597 2.133582221 1.922229899 1.57013181 1.213931024 1.865391973 2.242008782 1.428256246 2.351630216 1.668444958 1 7.163232627 -9.431006311 1.123227412 0.993085055 1.84259123 0.131608717 0.393759794 0.3673963 0.818349598 0.246859179 0.059925271 3.71E-10 9.431006311 0.849506175 EGGDGEEQDVGDAGR ddPTM_HeLa_Curcumin_4h_R1 2 EGGDGEEQDVGDAGR 15 0 Q8N1G4 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 0 0 ; ; 139.3 0.0016061 1060570 123.4 185.68 124.308 128.079 236.046 361.08 239.76 0 118.29 373.35 FALSE FALSE TRUE 113.6327598 201.7293518 128.9149638 127.549043 233.2313056 286.1879378 246.4870203 0 105.3138829 386.3238847 0.294138582 0.522176753 0.333696592 0.330160904 0.603719612 0.74079794 0.638032051 0 0.272605156 1 8.593667066 -9.369765207 1.015823506 1.010428096 0.440540811 0 0.299473854 0.361091266 0.647105422 0.152515638 0.036657286 4.27E-10 9.369765207 -0.569887286 EGGSKS(ph)DSEDITR ddPTM_HeLa_Curcumin_4h_R1 1 EGGSKSDSEDITR 13 1 E9PDC4;F5GYS8;H0YNY8;U3KPR8;O00470;O00470-2 E9PDC4 MEIS1 Homeobox protein Meis1 1 0 EGGS(0.01)KS(0.955)DS(0.034)EDIT(0.001)R 162.64 0.0019792 113000000 4513.1 3463.8 3512.9 3789.7 4240.4 4255.4 3465.7 2045.2 4039.6 3099.2 TRUE FALSE FALSE 4155.883373 3763.195438 3643.091164 3774.019226 4189.835999 3372.782072 3562.938215 2668.772065 3596.465987 3206.896969 1.295920453 1.173469392 1.136017527 1.176844551 1.30650783 1.051727606 1.1110236 0.832197632 1.121478495 1 11.64696229 -3.914353561 1.490425125 1.155511843 0.397669291 0.546842516 0.088810303 2.293394683 2.343992586 0.01736711 3.293480724 0.0001218 3.914353561 -0.757842552 EGHLS(ph)PDIVAEQK ddPTM_HeLa_Curcumin_4h_R1 3 EGHLSPDIVAEQK 13 0 B4DLR8;H3BNV2;P15559-3;P15559-2;P15559;H3BRK3 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 1 0 EGHLS(1)PDIVAEQK;EGHLS(1)PDIVAEQK;EGHLS(1)PDIVAEQK ;; 121.45 0.0011214 22339200 19718.6 17277.3 17135.6 17825.3 17909.4 21611.9 18821.9 20291.2 20756.2 19188.8 TRUE FALSE FALSE 18157.852 18770.67283 17770.66041 17751.54363 17695.8421 17129.34832 19349.99186 26477.89347 18479.29679 19855.60937 0.914494824 0.945358688 0.894994461 0.894031671 0.891226342 0.862695675 0.974535281 1.333522078 0.930683941 1 14.27725902 -4.267221732 4.37355335 0.937834278 1.36005224 0.903186715 0.040218548 0.05652243 2.593317135 0.007256449 0.073133268 5.40E-05 4.267221732 0.422217961 EGHSLEMENENLVENGADS(ph)DEDDNS(ph)FLKQQSPQEPK ddPTM_HeLa_Curcumin_4h_R1 1 EGHSLEMENENLVENGADSDEDDNSFLKQQSPQEPK 36 1 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 2 0 EGHSLEMENENLVENGADS(0.966)DEDDNS(0.517)FLKQQS(0.517)PQEPK 69.523 3.67E-06 7625800 703.7 641.63 681.43 688.81 659.12 791.41 850.74 815.76 885.04 787.34 TRUE FALSE FALSE 648.0014025 697.0896382 706.6843952 685.9598867 651.2604245 627.262645 874.6094748 1064.481469 787.9533263 814.7000064 0.795386519 0.855639662 0.867416705 0.841978497 0.799386792 0.769930821 1.073535618 1.306593176 0.967169903 1 9.670125109 -4.47568255 3.359389791 0.876765819 1.293939871 0.789546411 0.072047531 0.109728811 2.295188393 0.012862641 0.087166529 3.34E-05 4.47568255 0.417174052 EGHSLEMENENLVENGADS(ph)DEDDNSFLK ddPTM_HeLa_Curcumin_4h_R1 7 EGHSLEMENENLVENGADSDEDDNSFLK 28 0 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 EGHSLEMENENLVENGADS(0.999)DEDDNS(0.001)FLK;EGHSLEMENENLVENGADS(0.999)DEDDNS(0.001)FLK;EGHSLEMENENLVENGADS(0.997)DEDDNS(0.003)FLK;EGHSLEMENENLVENGADS(0.996)DEDDNS(0.004)FLK;EGHSLEMENENLVENGADS(1)DEDDNSFLK;EGHSLEMENENLVENGADS(1)DEDDNSFLK;EGHSLEMENENLVENGADS(1)DEDDNSFLK ;;;;;; 151.66 3.88E-11 465710200 14244.32 11599.03 14067.49 13063.46 15517.17 15038.35 12047.08 10907.99 12300.67 12008.47 TRUE FALSE FALSE 13116.86704 12601.59847 14588.84355 13009.40686 15332.13788 11919.22669 12385.08864 14233.78594 10951.31728 12425.76344 1.055618603 1.014150843 1.174080259 1.046970428 1.233899064 0.95923496 0.996726576 1.145505949 0.881339592 1 13.60104687 -8.201441265 0.694249546 1.005717536 1.081336675 0.217812816 0.089180761 0.987493983 1.042426118 0.032902726 0.019444908 6.29E-09 8.201441265 0.07561914 EGIDPTPYYWYTDQR ddPTM_HeLa_Curcumin_4h_R1 2 EGIDPTPYYWYTDQR 15 0 O43776 O43776 NARS "Asparagine--tRNA ligase, cytoplasmic" 0 0 ; ; 160.86 0.0025722 31341000 7215.7 6402.1 6208.7 6103.3 6375.2 7626 5703.4 5279.9 7153.6 6181.4 FALSE FALSE TRUE 6644.569731 6955.468997 6438.799884 6078.046162 6299.179904 6044.281637 5863.422054 6889.717204 6368.867977 6396.20319 1.038830308 1.087437155 1.006659684 0.950258455 0.984831113 0.944979616 0.916703532 1.077157338 0.995726338 1 12.64300005 -6.511099615 23.9891114 1.02512747 0.971261119 0.243030772 0.045904896 358.8143354 730754.1515 0.006891571 0.010167818 3.08E-07 6.511099615 -0.053866351 EGIILFK ddPTM_HeLa_Curcumin_4h_R1 1 EGIILFK 7 0 P05455 P05455 SSB Lupus La protein 0 0 111.28 0.013057 2581800 3490.6 2815.1 2745.3 3258.2 3001.8 4317.2 3414.4 3002.1 3043.5 2748.6 FALSE FALSE TRUE 3214.315327 3058.4247 2847.043233 3244.718432 2966.005496 3421.764055 3510.198875 3917.42647 2709.635664 2844.113645 1.130164166 1.075352493 1.001030053 1.140854001 1.042857588 1.203103842 1.234197825 1.377380428 0.952717086 1 11.4737634 -1.000000003 0.476142973 1.054963507 10.11729223 0.779404908 0.057720954 30.00590611 0.305556399 0.011742303 270.5028892 0.099999999 1.000000003 9.062328722 EGITGPPADSSKPIGPDDAIDALSSDFT(ph)CGSPTAAGKK ddPTM_HeLa_Curcumin_4h_R1 1 EGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKK 38 2 P20810-6;P20810-7;P20810-10;P20810-9;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;E7EVY3;H0YA91 P20810-6 CAST Calpastatin 1 0 EGITGPPADSSKPIGPDDAIDALS(0.046)S(0.046)DFT(0.559)CGS(0.316)PT(0.032)AAGKK 59.567 0.00011434 120070000 1966.1 1427.6 1358.4 1608 1467.8 1926 1574.9 1766 2013.4 1687.5 TRUE FALSE FALSE 1810.48111 1550.995383 1408.743499 1601.346522 1450.297444 1526.52589 1619.087455 2304.44527 1792.535057 1746.140499 1.036847328 0.888242031 0.806775571 0.917077705 0.830573166 0.874228557 0.927237789 1.319736454 1.026569774 1 10.76995393 -7.268264103 23.96379015 1.017400129 0.9249041 0.068221579 0.135458157 561.0398889 1969986.033 0.022483106 0.026033843 5.39E-08 7.268264103 -0.092496029 EGKPEIEGKPES(ph)EGEPGSETR ddPTM_HeLa_Curcumin_4h_R1 1 EGKPEIEGKPESEGEPGSETR 21 2 D6RD44;Q96EI5;Q96EI5-2 D6RD44 TCEAL4 Transcription elongation factor A protein-like 4 1 0 EGKPEIEGKPES(0.989)EGEPGS(0.01)ET(0.001)R 65.765 0.0033098 18030000 894.1 893.53 1019.8 1019.3 966.51 1244.8 1272.1 739.61 1165.7 911.35 TRUE FALSE FALSE 823.3310415 970.7627517 1057.594685 1015.082407 954.9849995 986.6144482 1307.791702 965.1136843 1037.825626 943.0193447 0.873079695 1.029419765 1.121498399 1.076417374 1.012688663 1.046229278 1.386813229 1.02342936 1.100534822 1 9.881143556 -6.056999709 0.674769956 0.943197385 1.175698654 0.101927618 0.118078581 0.631671104 0.537443923 0.023227882 0.07201986 8.77E-07 6.056999709 0.232501269 EGLELLK ddPTM_HeLa_Curcumin_4h_R1 1 EGLELLK 7 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 0 101.64 0.019944 19370000 4307.1 4400.6 4702.7 4147.8 4182 5846.6 4787.8 4905.8 4566.1 4816.5 FALSE FALSE TRUE 3966.18849 4780.968255 4876.986199 4130.637503 4132.132381 4633.949255 4922.132782 6401.555836 4065.210254 4983.873016 0.795804483 0.959287735 0.978553463 0.828800712 0.829100655 0.929788789 0.987611997 1.284454041 0.81567292 1 12.2830516 -4.213037018 2.049785444 0.90147162 1.425017425 0.74056393 0.069723754 0.400275231 1.629618396 0.012037554 0.405512469 6.12E-05 4.213037018 0.523545805 EGLELPEDEEEK ddPTM_HeLa_Curcumin_4h_R1 3 EGLELPEDEEEK 12 0 P08238;Q58FF7;Q58FF6;P07900;P07900-2;Q58FG0 P08238;P07900 HSP90AB1;HSP90AB3P;HSP90AB4P;HSP90AA1;HSP90AA5P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5 0 0 ;; ;; 193.96 3.16E-05 63583000 10535.4 9297.8 10909 9799.5 11858.4 11179.4 10427.8 9691.9 9124.1 8358.5 FALSE FALSE TRUE 9701.511973 10101.4604 11313.29714 9758.952266 11716.99632 8860.666422 10720.376 12646.91569 8123.209057 8648.957253 1.121697297 1.167939684 1.308053307 1.128338594 1.35472936 1.024477999 1.239499247 1.462247451 0.939212534 1 13.07831049 -1.00000037 0.039364196 0.33115117 2.581364331 0.516093126 0.110126059 441.5792112 1.338083976 21.38658538 67.27165555 0.099999915 1.00000037 2.250213161 EGLELPEDEEEKK ddPTM_HeLa_Curcumin_4h_R1 2 EGLELPEDEEEKK 13 1 P08238;Q58FF7;Q58FF6;P07900;P07900-2;Q58FG0 P08238;P07900 HSP90AB1;HSP90AB3P;HSP90AB4P;HSP90AA1;HSP90AA5P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5 0 0 ; ; 129.37 0.002483 16500100 3707.4 3316.6 3827.3 3439.5 3973 4864.8 3522 3637.2 4080 3469.7 FALSE FALSE TRUE 3413.955378 3603.272126 3969.143105 3425.26826 3925.62457 3855.785642 3620.817841 4746.165536 3632.434208 3590.271817 0.950890504 1.003620982 1.105527188 0.954041486 1.093405951 1.073953684 1.008507998 1.32195159 1.011743509 1 11.80987736 -1 0.870655257 0.992399152 126.1281188 0.67471028 0.058806019 306.0641999 0.733554525 0.009256564 75997.20117 0.1 1 125.1357196 EGLELPEDEEEKK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EGLELPEDEEEKKK 14 2 P08238;Q58FF7;P07900;P07900-2;Q58FG0 P08238;P07900 HSP90AB1;HSP90AB3P;HSP90AA1;HSP90AA5P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5 0 1 ; EGLELPEDEEEK(0.014)K(0.986)K;EGLELPEDEEEK(0.016)K(0.984)K 165.51 1.59E-05 41217000 10170.4 9612.9 9732.1 8922.3 16241 12890.6 12606.3 12995.5 15033.5 8592.5 FALSE TRUE FALSE 9365.402108 10443.79624 10092.78019 8885.381887 16047.33668 10216.94425 12959.99885 16957.76813 13384.36266 8891.088735 1.053347052 1.174636375 1.135156839 0.999358138 1.8048787 1.149121841 1.45763913 1.907276896 1.505368247 1 13.11814438 -1 0.292755558 0.995079898 7.750137446 0.337194555 0.256689722 22.43403511 0.286847011 0.074239081 79.79017909 0.1 1 6.755057549 EGLELPEDEEEKKK ddPTM_HeLa_Curcumin_4h_R1 4 EGLELPEDEEEKKK 14 2 P08238;Q58FF7;P07900;P07900-2;Q58FG0 P08238;P07900 HSP90AB1;HSP90AB3P;HSP90AA1;HSP90AA5P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5 0 0 ;;; ;;; 163.99 0.0001011 150400700 20951.5 16757.8 20149.4 20122.6 23337.7 24163.7 20170.3 19100.1 18777.1 18703.6 FALSE FALSE TRUE 19293.16667 18206.26956 20896.15449 20039.33801 23059.41317 19151.87624 20736.22433 24923.63256 16717.29911 19353.54871 0.996880053 0.94071996 1.079706611 1.035434809 1.191482426 0.989579561 1.071443002 1.287806848 0.863784692 1 14.24031051 -1 0.474051777 1.000684898 7.470143352 0.520647005 0.080004444 46.51605746 0.47599813 0.013352128 297.7223633 0.1 1 6.469458454 EGLELPEDEEEKKKQEEK ddPTM_HeLa_Curcumin_4h_R1 1 EGLELPEDEEEKKKQEEK 18 3 P07900;P07900-2;Q58FG0 P07900 HSP90AA1;HSP90AA5P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5 0 0 41.088 0.015101 7519400 4908 3828.5 4154.3 4314.7 4415.6 5419.5 4129.6 4126.8 4849.2 3871.9 FALSE FALSE TRUE 4519.526621 4159.418481 4308.262012 4296.846915 4362.946854 4295.43461 4245.465462 5385.042323 4317.254892 4006.448237 1.128063151 1.038181011 1.075332004 1.072482823 1.088981211 1.072130315 1.059658134 1.344093822 1.077576606 1 11.96810812 EGLGRLRVPT(ph)GEGAGIST(ph)RS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 EGLGRLRVPTGEGAGISTRSPR 22 3 C9JXV4;E7EPP8;P05108 C9JXV4 CYP11A1 "Cholesterol side-chain cleavage enzyme, mitochondrial" 3 0 EGLGRLRVPT(1)GEGAGIS(0.077)T(0.962)RS(0.962)PR 56.332 0.0063977 11491000 926.29 376.25 269.73 340.63 526.72 1501.3 526.31 418.37 692.41 401.34 TRUE FALSE FALSE 852.9731691 408.7713735 279.7264311 339.2205633 520.439208 1189.913457 541.0768421 545.9290871 616.4543553 415.2865351 2.0539389 0.984311647 0.673574526 0.816834967 1.25320511 2.865283018 1.302900037 1.314584127 1.484407278 1 8.697963286 -9.799276197 1.809004873 0.998609309 1.516272353 0 0.62930667 0.822926276 4.873319444 0.493077345 0.102881712 1.59E-10 9.799276197 0.517663043 T(ph)MSVQQPDPPAANPKPER ddPTM_HeLa_Curcumin_4h_R1 1 TMSVQQPDPPAANPKPER 18 1 Q9BZ71;Q9BZ71-3;Q9BZ71-2 Q9BZ71 PITPNM3 Membrane-associated phosphatidylinositol transfer protein 3 1 0 T(0.565)MS(0.435)VQQPDPPAANPKPER 80.459 0.0035003 9839800 1931.7 1439.1 2057.3 1858.9 2013.8 2168.8 2447.5 3569.8 2102.4 1912.3 TRUE FALSE FALSE 1778.803907 1563.489391 2133.545348 1851.208364 1989.78675 1718.966433 2516.170263 4658.215587 1871.77198 1978.752283 0.898952295 0.790139021 1.078227612 0.935543262 1.005576478 0.868712293 1.27159437 2.354117606 0.945935475 1 10.9503753 -4.27232366 2.540360088 0.947030291 2.637800281 0.967299767 0.0779917 0.057968079 0.477012286 0.010889626 0.20765939 5.34E-05 4.27232366 1.690769989 up EGLPVALDK ddPTM_HeLa_Curcumin_4h_R1 1 EGLPVALDK 9 0 Q9Y224 Q9Y224 C14orf166 UPF0568 protein C14orf166 0 0 111.06 0.0032754 2382700 3615.6 2899.4 2838.7 3219.2 3569.4 3414.3 3199.6 3198.2 3127.3 2834.7 FALSE FALSE TRUE 3329.421445 3150.011217 2943.904719 3205.879803 3526.837236 2706.135693 3289.372165 4173.316457 2784.243014 2933.205614 1.13507946 1.073914219 1.003647581 1.092961158 1.202383229 0.922586429 1.121425702 1.422783468 0.949215084 1 11.51826249 -4.284296329 4.018201795 1.064765619 1.447269266 0.648672827 0.081703918 0.096541218 3.20195947 0.010589072 0.102507528 5.20E-05 4.284296329 0.382503646 GNAEGS(ph)SDEEGKLVIDEPAKEK ddPTM_HeLa_Curcumin_4h_R1 1 GNAEGSSDEEGKLVIDEPAKEK 22 2 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 0 GNAEGS(0.616)S(0.384)DEEGKLVIDEPAKEK 59.046 0.0078579 18440000 1213.2 963.63 894.72 1105.6 1245.8 1172.4 1126.2 1404.1 1112.2 869.12 TRUE FALSE FALSE 1117.17394 1046.921883 927.8791103 1101.02532 1230.944649 929.2310243 1157.798141 1832.203626 990.1944426 899.3218553 1.242240398 1.164123697 1.03175421 1.224283958 1.36874762 1.033257469 1.287412437 2.037316913 1.101045679 1 9.812693719 -4.271516059 3.18773053 1.136004846 2.158902002 0.858650923 0.107840215 0.09866721 1.571320654 0.0173801 0.24690519 5.35E-05 4.271516059 1.022897156 up ETEAAPTS(ph)PPIVPLK ddPTM_HeLa_Curcumin_4h_R1 1 ETEAAPTSPPIVPLK 15 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;Q7Z3B3-4;Q7Z3B3-2 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 0 ETEAAPT(0.021)S(0.979)PPIVPLK 104.81 0.0027782 27824000 4767 3539.7 3861.3 3511.3 3920.2 4699.4 4619.3 6086.7 4089 3701.3 TRUE FALSE FALSE 4389.68692 3845.655895 4004.403175 3496.771171 3873.454175 3724.691467 4748.905126 7942.50681 3640.44693 3829.919899 1.146156326 1.004108701 1.045557944 0.913014179 1.011366889 0.972524639 1.239948942 2.073804941 0.950528216 1 11.9030985 -4.270653678 2.893003319 1.044068142 2.241959696 0.955163319 0.068966952 0.064134721 0.763494568 0.010889208 0.177020586 5.36E-05 4.270653678 1.197891554 up EGLTSIEEVTK ddPTM_HeLa_Curcumin_4h_R1 2 EGLTSIEEVTK 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 182.16 9.73E-12 10156100 4067.7 3868.2 3912.3 3556.3 3814.4 5372.8 4516.4 3692.4 4987.6 3970.1 FALSE FALSE TRUE 3745.737253 4202.549972 4057.29328 3541.584973 3768.915771 4258.420716 4643.118029 4818.195762 4440.472758 4108.060679 0.911801832 1.023000949 0.987642003 0.862106295 0.917444036 1.036601221 1.130245727 1.172863825 1.080917032 1 12.00424178 -4.868884929 2.553958546 0.95515402 1.162003095 0.585188549 0.060253141 0.116532559 1.493747061 0.00740162 0.030430184 1.35E-05 4.868884929 0.206849075 EGLVFS(ph)RLSPEYYDLAR ddPTM_HeLa_Curcumin_4h_R1 1 EGLVFSRLSPEYYDLAR 17 1 P22749-2 P22749-2 1 0 EGLVFS(0.946)RLS(0.054)PEYYDLAR 60.968 0.014512 4333200 1200.7 1188.3 1307 1179.6 1234.4 1525 1280 885.9 1378.6 1251.1 TRUE FALSE FALSE 1105.663328 1291.011357 1355.43857 1174.719128 1219.680586 1208.69781 1315.913355 1156.006832 1227.371029 1294.575632 0.854073954 0.997246762 1.047013814 0.907416376 0.94214703 0.933663341 1.016482408 0.89296199 0.948087542 1 10.33826354 EGLVFSRLS(ph)PEYYDLAR ddPTM_HeLa_Curcumin_4h_R1 1 EGLVFSRLSPEYYDLAR 17 1 P22749-2 P22749-2 1 0 EGLVFS(0.381)RLS(0.619)PEYYDLAR 77.42 0.0049526 4356800 1158.5 1031.5 853.69 994.09 1140.3 1438.5 1150.7 1022.7 1038 915.42 TRUE FALSE FALSE 1066.803503 1120.658264 885.3285024 989.976719 1126.702667 1140.138885 1182.985545 1334.516522 924.1339969 947.2307769 1.126233996 1.183088948 0.934649215 1.045127273 1.189470079 1.203654814 1.248888417 1.408861024 0.975616523 1 9.887572147 -1.000000016 0.414593797 1.052080512 7.555841344 0.713564106 0.073726679 29.10919092 0.335859615 0.018211447 158.0040055 0.099999996 1.000000016 6.503760831 EGMNIVEAMER ddPTM_HeLa_Curcumin_4h_R1 4 EGMNIVEAMER 11 0 P62937;P62937-2 P62937 PPIA "Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed" 0 0 ;;; ;;; 190.57 4.00E-07 35964900 6743.8 5251.6 6126.3 5912.5 6072.7 7969.4 6087.8 5702.9 6853 5451.31 FALSE FALSE TRUE 6210.021114 5705.524903 6353.346067 5888.035642 6000.287019 6316.456606 6258.607284 7441.687957 6101.243045 5640.742617 1.100922615 1.011484709 1.126331495 1.043840509 1.063740615 1.119791672 1.10953605 1.319274511 1.081638263 1 12.46166939 -1.000000052 0.802789151 1.051366018 67.87155255 0.78289977 0.039493467 179.2415885 0.579345039 0.007157069 21802.8197 0.099999988 1.000000052 66.82018653 EGMNPSYDEY(ph)ADSDEDQHDAYLER ddPTM_HeLa_Curcumin_4h_R1 1 EGMNPSYDEYADSDEDQHDAYLER 24 0 Q08945;A0A0U1RRK2 Q08945 SSRP1 FACT complex subunit SSRP1 1 0 EGMNPS(0.017)Y(0.053)DEY(0.516)ADS(0.414)DEDQHDAYLER 66.017 0.00044581 7210700 1115 1260.4 1165.3 1394.8 1275.1 1334.7 1130 1246.1 1377.9 1389.5 TRUE FALSE FALSE 1026.746573 1369.34336 1208.487043 1389.028687 1259.895265 1057.868175 1161.704759 1626.030154 1226.747817 1437.785022 0.714116894 0.952397848 0.840519984 0.966089274 0.876275136 0.735762412 0.807982237 1.130927176 0.853220613 1 10.48963226 EGMNPSYDEYADS(ph)DEDQHDAYLER ddPTM_HeLa_Curcumin_4h_R1 18 EGMNPSYDEYADSDEDQHDAYLER 24 0 Q08945;A0A0U1RRK2 Q08945 SSRP1 FACT complex subunit SSRP1 1 0 EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEY(0.003)ADS(0.996)DEDQHDAYLER;EGMNPS(0.001)YDEY(0.004)ADS(0.995)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPS(0.019)Y(0.036)DEY(0.011)ADS(0.934)DEDQHDAY(0.001)LER;EGMNPSY(0.001)DEY(0.002)ADS(0.997)DEDQHDAYLER;EGMNPS(0.003)Y(0.003)DEY(0.024)ADS(0.97)DEDQHDAYLER;EGMNPSYDEY(0.004)ADS(0.995)DEDQHDAYLER;EGMNPSYDEY(0.001)ADS(0.999)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEY(0.001)ADS(0.999)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEY(0.002)ADS(0.997)DEDQHDAYLER;EGMNPSY(0.001)DEY(0.005)ADS(0.993)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER;EGMNPSYDEY(0.001)ADS(0.999)DEDQHDAYLER;EGMNPSYDEYADS(1)DEDQHDAYLER ;;;;;;;;;;;;;;;;; 168.78 4.63E-10 9775113200 48448.6 46197.63 42873.1 47384.71 44880.25 50617.67 42044.18 41033.85 50888.86 45946.43 TRUE FALSE FALSE 44613.84219 50190.74728 44462.0148 47188.64463 44345.08233 40118.99466 43223.82653 53544.88197 45306.47938 47543.06502 0.93838801 1.055690189 0.93519454 0.992545277 0.932735033 0.843845357 0.90915103 1.126239588 0.952956637 1 15.53694729 -5.753360886 24.55883317 0.975669978 0.942064954 0.019240317 0.074539804 419.1601642 1274245.277 0.010551018 0.020801713 1.76E-06 5.753360886 -0.033605023 EGNGTSNSTLSGPGLDSKPGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 EGNGTSNSTLSGPGLDSKPGKR 22 2 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 0 1 ; EGNGTSNSTLSGPGLDSK(0.003)PGK(0.997)R;EGNGTSNSTLSGPGLDSK(0.001)PGK(0.999)R 218.38 5.25E-30 8640200 1026.88 1024.1 1280.59 781.61 1088.41 1391.77 713.35 922.13 1022.22 1148.48 FALSE TRUE FALSE 945.6013644 1112.618641 1328.049792 778.3759049 1075.431422 1103.101214 733.3646811 1203.283192 910.0850235 1188.389595 0.795699801 0.936240645 1.117520549 0.654983777 0.904948534 0.928231969 0.617107962 1.012532588 0.765813692 1 10.21479216 -6.249645728 24.98031862 0.91863911 0.822427962 0.105344433 0.144668829 1428.028366 3024729.86 0.021060954 0.034743521 5.63E-07 6.249645728 -0.096211148 EGNGTVMGAELR ddPTM_HeLa_Curcumin_4h_R1 1 EGNGTVMGAELR 12 0 P05976-2;P05976;P08590 P05976-2 MYL1;MYL3 "Myosin light chain 1/3, skeletal muscle isoform;Myosin light chain 3" 0 0 93.839 0.01602 1626500 189.58 332.71 404.26 125.77 330.23 354.08 275.41 332.24 345.3 447.59 FALSE FALSE TRUE 174.574543 361.4679699 419.2422312 125.2495971 326.2922229 280.6398167 283.1372634 433.5384466 307.4214539 463.1437192 0.376933845 0.780466095 0.905209795 0.270433543 0.704516135 0.605945423 0.611337802 0.936077569 0.663771182 1 8.855316139 -9.596844131 1.397912045 0.999587411 0.610760458 0 0.223989044 0.397229065 1.395069834 0.143772625 0.033442579 2.53E-10 9.596844131 -0.388826953 EGNTT(ph)EDDFPSS(ph)PGNGNK ddPTM_HeLa_Curcumin_4h_R1 1 EGNTTEDDFPSSPGNGNK 18 0 Q15007 Q15007 WTAP Pre-mRNA-splicing regulator WTAP 2 0 EGNT(0.035)T(0.814)EDDFPS(0.232)S(0.919)PGNGNK 91.622 0.011336 5338000 1942.2 1467.4 1793.7 1612 1665.3 1980.1 1422.5 1362.7 1707.6 1738.8 TRUE FALSE FALSE 1788.472821 1594.235517 1860.1761 1605.329971 1645.442385 1569.40494 1462.411522 1778.180957 1520.280552 1799.223171 0.994025005 0.886068801 1.033877359 0.892235048 0.914529344 0.87226808 0.812801628 0.988304834 0.84496497 1 10.81315843 -6.404065298 0.737809409 0.99804648 0.881890353 0 0.07450783 0.460688184 0.497875365 0.011007997 0.024064506 3.94E-07 6.404065298 -0.116156127 EGNTTEDDFPS(ph)S(ph)PGNGNK ddPTM_HeLa_Curcumin_4h_R1 1 EGNTTEDDFPSSPGNGNK 18 0 Q15007 Q15007 WTAP Pre-mRNA-splicing regulator WTAP 2 0 EGNT(0.001)T(0.008)EDDFPS(0.992)S(0.999)PGNGNK 129.74 0.0005312 5086100 3482.2 3070.1 3403 3595.1 3487.7 3317.1 2679.2 2712.7 3706.3 3794.2 TRUE FALSE FALSE 3206.580196 3335.465764 3529.118174 3580.224429 3446.111455 2629.096069 2754.371141 3539.789742 3299.728163 3926.048168 0.816744996 0.849573317 0.898898338 0.911915564 0.877755776 0.669654563 0.701563257 0.901616483 0.840470626 1 11.93886216 -13.52287875 0.169773946 1.718850059 0.772637851 0.058137092 0.090943776 43.63293813 0.483687114 10.42054277 0.133894603 3.00E-14 13.52287875 -0.946212207 EGNTTEDDFPS(ph)SPGNGNK ddPTM_HeLa_Curcumin_4h_R1 2 EGNTTEDDFPSSPGNGNK 18 0 Q15007 Q15007 WTAP Pre-mRNA-splicing regulator WTAP 1 0 EGNTTEDDFPS(0.5)S(0.5)PGNGNK;EGNTTEDDFPS(0.5)S(0.5)PGNGNK ; 231.86 9.12E-24 668290000 8219.6 7224.8 6784.4 7481.5 7375.7 8302.2 7011.3 6103.9 8056.7 7134.6 TRUE FALSE FALSE 7569.009987 7849.279519 7035.835832 7450.543535 7287.749595 6580.230135 7208.018208 7964.951011 7172.900167 7382.526819 1.025260073 1.063223976 0.95303898 1.009213203 0.987161953 0.891324921 0.97636194 1.078892256 0.971605027 1 12.84989898 -6.739324977 24.99932281 1.016108846 0.979638271 0.093280615 0.048830128 390.0420094 440923.6385 0.007341361 0.010377666 1.82E-07 6.739324977 -0.036470575 EGNTTEDDFPSS(ph)PGNGNK ddPTM_HeLa_Curcumin_4h_R1 2 EGNTTEDDFPSSPGNGNK 18 0 Q15007 Q15007 WTAP Pre-mRNA-splicing regulator WTAP 1 0 EGNTTEDDFPS(0.003)S(0.997)PGNGNK;EGNTTEDDFPS(0.01)S(0.99)PGNGNK ; 255.72 4.81E-42 31627000 4639.7 3490 3798.5 3851.1 3801.2 4579.6 3508.1 3305.8 4827.6 3737.7 TRUE FALSE FALSE 4272.462849 3791.660049 3939.275752 3835.165169 3755.873173 3629.739337 3606.527844 4313.723202 4298.024358 3867.584797 1.104684984 0.980368951 1.018536363 0.991617604 0.971115921 0.938502846 0.932501298 1.115353232 1.11129415 1 11.91721721 -7.225040544 24.58028505 1.049434586 0.988317786 0.263876701 0.056869276 594.4881385 401460.9685 0.009830473 0.012039643 5.96E-08 7.225040544 -0.0611168 EGPEEPGLAKQDS(ph)FR ddPTM_HeLa_Curcumin_4h_R1 2 EGPEEPGLAKQDSFR 15 1 J3KPS2;A0A494C1T9;Q6ZRV2 J3KPS2 FAM83H Protein FAM83H 1 0 EGPEEPGLAKQDS(1)FR;EGPEEPGLAKQDS(1)FR ; 106.31 0.0011453 32463000 4205.6 3577.6 3230.7 3682.8 3525.3 6238.9 5196 2083.9 4875.6 3882.8 TRUE FALSE FALSE 3872.722322 3886.831803 3350.432584 3667.561549 3483.2631 4944.881813 5341.785776 2719.271517 4340.758878 4017.727011 0.963908775 0.967420582 0.833912452 0.912844885 0.866973563 1.230766003 1.329554188 0.676818387 1.080401647 1 11.97216383 -5.270122666 24.99058476 0.957845969 1.104096995 0.104599315 0.170883208 876.9381885 2523837.351 0.022163052 0.050272889 5.37E-06 5.270122666 0.146251027 EGPEPPEEVPPPT(ph)TPPVPK ddPTM_HeLa_Curcumin_4h_R1 1 EGPEPPEEVPPPTTPPVPK 19 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 0 EGPEPPEEVPPPT(0.5)T(0.5)PPVPK 144.41 0.00043303 13687000 8705.8 7354.3 8620.9 8177.2 8700.4 9560.7 8547.3 8903.2 8186 7031.1 TRUE FALSE FALSE 8016.726744 7989.972922 8940.398138 8143.364913 8596.653412 7577.703049 8787.114234 11617.74469 7288.01628 7275.430202 1.101890407 1.098213123 1.228848039 1.119296686 1.181600699 1.041547075 1.207779333 1.596846423 1.001729943 1 12.82881684 EGPGEEHFEDMAS(ph)DEDMKPK ddPTM_HeLa_Curcumin_4h_R1 1 EGPGEEHFEDMASDEDMKPK 20 1 Q99856 Q99856 ARID3A AT-rich interactive domain-containing protein 3A 1 0 EGPGEEHFEDMAS(1)DEDMKPK 61.524 0.0044239 5967800 1878.5 1472.5 1866.6 1887.7 1877.6 2291.4 1906 1631.4 2003.5 1775.7 TRUE FALSE FALSE 1729.814743 1599.776339 1935.777838 1879.889198 1855.210846 1816.137811 1959.47723 2128.80635 1783.721063 1837.405443 0.941444225 0.870671383 1.053538752 1.023121601 1.009690514 0.988425183 1.066437045 1.158593689 0.970782507 1 10.84345429 -1 0.56496325 0.970708052 10.40770448 0.605211445 0.045965975 69.53358887 0.554958608 0.008947187 803.9121885 0.1 1 9.436996428 EGPGS(ph)EPDSQVDGGLSGASLGEK ddPTM_HeLa_Curcumin_4h_R1 1 EGPGSEPDSQVDGGLSGASLGEK 23 0 Q5JSZ5;A0A494C0D3;H0Y412;A0A494C065 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 EGPGS(1)EPDSQVDGGLSGASLGEK 130.62 4.07E-06 7592500 7909 6322.4 7504.9 6814.1 7553.7 9094.5 6482.9 3810.5 7847 7002.1 TRUE FALSE FALSE 7282.994304 6868.880084 7783.038196 6785.90506 7463.627061 7208.198184 6664.792726 4972.303909 6986.203732 7245.422454 1.005185598 0.948030308 1.074200745 0.936578247 1.030116202 0.994862374 0.919862543 0.686268322 0.964223105 1 12.8228541 -4.243813003 2.089005468 1.000842678 0.58890069 0.853858407 0.03820926 0.157196311 0.717516174 0.004433129 0.123649221 5.70E-05 4.243813003 -0.411941988 EGPLGWSSDGSLGSVLLDS(ph)PSSPR ddPTM_HeLa_Curcumin_4h_R1 1 EGPLGWSSDGSLGSVLLDSPSSPR 24 0 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 0 EGPLGWSSDGS(0.002)LGS(0.107)VLLDS(0.814)PS(0.064)S(0.012)PR 86.304 0.00019206 0 277.52 344.21 334.7 214.64 408.14 456.33 369.47 321.71 440.33 404.43 TRUE FALSE FALSE 255.5539992 373.9619786 347.1042764 213.7518766 403.2731971 361.6820141 379.8363338 419.797898 392.0269007 418.4839124 0.610666244 0.893611361 0.829432784 0.510776807 0.963652807 0.864267427 0.907648592 1.003139871 0.936778904 1 8.709028353 EGPLGWSSDGSLGSVLLDSPS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 EGPLGWSSDGSLGSVLLDSPSSPR 24 0 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 0 EGPLGWSSDGSLGSVLLDS(0.393)PS(0.439)S(0.168)PR;EGPLGWSSDGSLGSVLLDS(0.113)PS(0.68)S(0.207)PR ; 182.4 1.45E-11 11099700 3000.59 3260.7 3296.4 2872.6 3133 3884.4 3622.2 4484.2 3714 3168.4 TRUE FALSE FALSE 2763.090135 3542.540379 3418.567484 2860.713942 3095.641021 3078.731654 3723.829183 5851.411937 3306.583492 3278.501664 0.842790524 1.080536398 1.04272251 0.872567482 0.944224325 0.939066674 1.135832635 1.78478236 1.008565446 1 11.67882091 -4.243790197 2.256345766 0.941559307 2.023078053 0.918753067 0.072564806 0.137283546 0.770195823 0.011593137 0.299022618 5.70E-05 4.243790197 1.081518746 SWDSS(ph)SPVDRPEPEAASPTTR ddPTM_HeLa_Curcumin_4h_R1 2 SWDSSSPVDRPEPEAASPTTR 21 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 S(0.004)WDS(0.103)S(0.446)S(0.446)PVDRPEPEAASPTTR;S(0.01)WDS(0.169)S(0.619)S(0.202)PVDRPEPEAASPTTR ; 77.543 0.00065172 571210000 2401.26 2134.76 1892.44 1614.19 2071.4 2288.12 878.04 469.314 1947.82 1616.04 TRUE FALSE FALSE 2211.197737 2319.279142 1962.575491 1607.510909 2046.699908 1813.53812 902.6754393 612.4056781 1734.149019 1672.19727 1.322330671 1.386965033 1.173650697 0.96131655 1.223958408 1.084524029 0.539813966 0.366228129 1.037048111 1 10.70752934 -4.728163368 3.123411112 1.165239398 0.3934275 0.828369032 0.128125809 0.083146785 1.609240471 0.021840783 0.096129681 1.87E-05 4.728163368 -0.771811898 down EGPTVETK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 EGPTVETKR 9 1 Q96AT1 Q96AT1 KIAA1143 Uncharacterized protein KIAA1143 0 1 ; EGPTVETK(1)R;EGPTVETK(1)R 113.66 0.00081814 16760300 4316.8 4570.9 4005.1 3914.2 3994.1 6923.5 5636.7 7941.1 4675.9 3875.1 FALSE TRUE FALSE 3975.120725 4965.988228 4153.532529 3898.004078 3946.472966 5487.488056 5794.850632 10362.30483 4162.965469 4009.759437 0.991361399 1.238475352 1.03585579 0.972129161 0.984216891 1.368532986 1.445186606 2.584270951 1.038208285 1 11.96929997 EGPVGGES(ph)DSEEMFEK ddPTM_HeLa_Curcumin_4h_R1 1 EGPVGGESDSEEMFEK 16 0 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 0 EGPVGGES(0.94)DS(0.06)EEMFEK 125.45 0.00060169 3193500 937.15 833.12 842.45 863.89 1101.9 1317.6 789.59 619.86 1106.9 865.13 TRUE FALSE FALSE 862.9735886 905.1311805 873.6719381 860.3154521 1088.760562 1044.314908 811.7437703 808.8524605 985.4758393 895.1932031 0.9640082 1.011101489 0.975959084 0.961038856 1.216229701 1.16658047 0.906780534 0.903550717 1.100852683 1 9.806055272 EGPVLATS(ph)SGAGVFK ddPTM_HeLa_Curcumin_4h_R1 2 EGPVLATSSGAGVFK 15 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 0 EGPVLAT(0.045)S(0.879)S(0.075)GAGVFK;EGPVLAT(0.428)S(0.525)S(0.047)GAGVFK ; 184 3.28E-05 31145000 7785.6 3960.9 6691.5 7018.8 6074.5 6483.2 4135 3426.3 4848.6 5097.3 TRUE FALSE FALSE 7169.361545 4303.262547 6939.492876 6989.758065 6002.065555 5138.511239 4251.016971 4470.963097 4316.720711 5274.430796 1.359267345 0.815872407 1.315685644 1.325215618 1.137955125 0.974230479 0.805966963 0.847667411 0.818423993 1 12.36479969 -5.073774956 2.613201538 1.167904435 0.827968719 0.228038579 0.189645264 0.22697138 3.007090515 0.025630142 0.083752566 8.44E-06 5.073774956 -0.339935716 EGPYS(ph)ISVLYGDEEVPR ddPTM_HeLa_Curcumin_4h_R1 1 EGPYSISVLYGDEEVPR 17 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 EGPYS(0.975)IS(0.025)VLYGDEEVPR 228.9 4.20E-22 6192900 778.97 530.82 544.94 895.54 848.98 952.66 633.31 635.44 790.87 728.02 TRUE FALSE FALSE 717.3137025 576.7017155 565.1359558 891.8344928 838.856468 755.0675773 651.0789741 829.1827308 704.1135397 753.3186408 0.952204902 0.765548181 0.750195104 1.183874186 1.113548003 1.002321642 0.864280981 1.100706508 0.93468222 1 9.557116419 -6.24207872 24.99562602 0.942101492 1.043019121 0.291673813 0.115435886 1351.469107 1744817.817 0.01908986 0.031625995 5.73E-07 6.24207872 0.100917629 EGPYSIS(ph)VLYGDEEVPR ddPTM_HeLa_Curcumin_4h_R1 1 EGPYSISVLYGDEEVPR 17 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 EGPYS(0.148)IS(0.852)VLYGDEEVPR 163.9 0.00012262 1933500 557.46 443.69 558.81 766.37 784.89 934.41 642.38 617.15 615.12 684.55 TRUE FALSE FALSE 513.3364528 482.0405866 579.5199902 763.198964 775.5306994 740.602833 660.4034539 805.316194 547.642875 708.3380615 0.724705449 0.680523344 0.818140407 1.077450169 1.094859561 1.045549962 0.932328064 1.136909391 0.773137721 1 9.468294255 -6.261062053 24.99983153 0.84593665 1.051890507 0.618516746 0.097943672 28.3737721 1879900.008 0.019840712 0.031622962 5.48E-07 6.261062053 0.205953857 EGPYSISVLY(ph)GDEEVPRSPFK ddPTM_HeLa_Curcumin_4h_R1 1 EGPYSISVLYGDEEVPRSPFK 21 1 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 EGPY(0.008)S(0.04)IS(0.04)VLY(0.895)GDEEVPRS(0.018)PFK 106.87 0.00023083 241030000 2090.8 2044.2 2278.7 2526.7 2194 3532.3 4488.9 2644.6 2833 1705.2 TRUE FALSE FALSE 1925.310974 2220.891539 2363.150627 2516.245185 2167.837983 2799.661163 4614.846453 3450.926366 2522.226988 1764.455573 1.091164325 1.25868374 1.339308658 1.426074549 1.228615793 1.586699719 2.615450637 1.955802355 1.429464718 1 10.78500739 -4.981373738 0.69738905 1.061899493 2.562275056 0.641156008 0.270849141 0.476398958 0.275367648 0.041548712 0.465242422 1.04E-05 4.981373738 1.500375563 EGPYSISVLYGDEEVPR ddPTM_HeLa_Curcumin_4h_R1 2 EGPYSISVLYGDEEVPR 17 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 245.5 8.57E-30 75326000 3053 2517.34 2443.55 2935.47 2950.2 3678.9 2471.93 2919.69 3229.1 2727.04 FALSE FALSE TRUE 2811.351828 2734.927653 2534.110113 2923.323803 2915.020792 2915.85467 2541.285703 3809.89004 2874.875809 2821.804437 0.996295771 0.96921233 0.898045973 1.035976755 1.033034307 1.03332982 0.900588882 1.350160908 1.018807601 1 11.46240229 -4.252385354 24.99913029 0.991891454 1.350161093 0.832436294 0.048806249 332.5270779 918123.7303 0.006277983 0.10267088 5.59E-05 4.252385354 0.358269639 EGPYSISVLYGDEEVPRS(ph)PFK ddPTM_HeLa_Curcumin_4h_R1 3 EGPYSISVLYGDEEVPRSPFK 21 1 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 EGPYS(0.001)IS(0.008)VLY(0.114)GDEEVPRS(0.877)PFK;EGPYSISVLYGDEEVPRS(1)PFK;EGPYSISVLYGDEEVPRS(1)PFK ;; 100.94 6.09E-05 448697000 3747.19 3058.27 2936.14 3338.71 3750.58 5722.24 5955.33 3864.42 4250.61 2560.45 TRUE FALSE FALSE 3450.595957 3322.613231 3044.955931 3324.895303 3705.856783 4535.382921 6122.420532 5042.663868 3784.328718 2649.425447 1.302394057 1.254088216 1.149289154 1.254949561 1.398739786 1.711836401 2.310848391 1.903304686 1.428358259 1 11.37146382 -5.204368902 1.665000944 1.161608173 2.120951601 0.822770975 0.157786491 0.099128373 0.514233267 0.022729447 0.084203002 6.25E-06 5.204368902 0.959343428 EGQEDQGLTK ddPTM_HeLa_Curcumin_4h_R1 3 EGQEDQGLTK 10 0 A0A0U1RRM4;A0A0D9SF20;A0A087WUW5;O95758-7;O95758-1;O95758-6;O95758-2;O95758;O95758-5;O95758-4;A6NLN1;P26599;P26599-2;P26599-3 A0A0U1RRM4;A6NLN1 PTBP1;PTBP3 Polypyrimidine tract-binding protein 3;Polypyrimidine tract-binding protein 1 0 0 ;; ;; 166.69 2.68E-12 15882100 5886.4 5533.35 5547.25 6475.7 5716.07 7466.9 5835.42 5654.6 6605.3 6153.7 FALSE FALSE TRUE 5420.485229 6011.628118 5752.835965 6448.905269 5647.909599 5918.180771 5999.14618 7378.661509 5880.715116 6367.540617 0.851268261 0.944105186 0.903462783 1.012778034 0.886984464 0.929429607 0.942144941 1.158793002 0.923545756 1 12.63652054 -4.260747786 4.846174298 0.930499006 1.171249681 0.689857082 0.045538295 0.098840103 6.735631567 0.008110977 0.079871484 5.49E-05 4.260747786 0.240750675 EGQHYPER ddPTM_HeLa_Curcumin_4h_R1 1 EGQHYPER 8 0 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 0 0 91.087 0.01618 2942400 1329.8 1322.7 1038.5 1073.2 825.69 1558.3 942.89 993.9 1287.4 1193.1 FALSE FALSE TRUE 1224.544927 1437.028294 1076.987724 1068.759383 815.844186 1235.091014 969.3449557 1296.935535 1146.175441 1234.560136 0.991887629 1.164000239 0.872365543 0.865700545 0.660837947 1.000430014 0.785174353 1.050524391 0.928407947 1 10.2697814 -6.570653933 24.99649133 1.009103527 0.86362526 0.282913938 0.114809582 104.6182335 54736.98337 0.01624891 0.022979433 2.69E-07 6.570653933 -0.145478267 EGQPSPADEKGNDS(ph)DGEGESDDPEK ddPTM_HeLa_Curcumin_4h_R1 2 EGQPSPADEKGNDSDGEGESDDPEK 25 1 O75351;K7EKZ3 O75351 VPS4B Vacuolar protein sorting-associated protein 4B 1 0 EGQPSPADEKGNDS(0.695)DGEGES(0.305)DDPEK;EGQPSPADEKGNDS(0.815)DGEGES(0.185)DDPEK ; 71.634 0.00028279 130190400 8123.6 6959.9 8742.9 7846.1 10279.9 9231.1 7665.4 7671 6651.1 6680.7 TRUE FALSE FALSE 7480.608488 7561.482743 9066.919565 7813.634917 10157.31891 7316.465804 7880.470494 10009.85259 5921.49097 6912.853828 1.082130286 1.093829398 1.311602963 1.130305242 1.469338013 1.058385724 1.139973546 1.448005822 0.856591376 1 12.7550657 -7.075357189 1.298618123 1.030484339 1.251706628 0.434225484 0.13896377 0.314045504 1.026297017 0.023253562 0.02994424 8.41E-08 7.075357189 0.221222288 EGQPSPADEKGNDS(ph)DGEGESDDPEKK ddPTM_HeLa_Curcumin_4h_R1 4 EGQPSPADEKGNDSDGEGESDDPEKK 26 2 O75351;K7EKZ3 O75351 VPS4B Vacuolar protein sorting-associated protein 4B 1 0 EGQPS(0.083)PADEKGNDS(0.917)DGEGESDDPEKK;EGQPS(0.001)PADEKGNDS(0.99)DGEGES(0.009)DDPEKK;EGQPSPADEKGNDS(0.999)DGEGES(0.001)DDPEKK;EGQPSPADEKGNDS(0.78)DGEGES(0.22)DDPEKK ;;; 106.99 1.40E-07 58543100 12175.4 9713.6 10082.9 11695.7 11288.6 12101.6 10619.2 10721.8 11302.1 9994.2 TRUE FALSE FALSE 11211.70424 10553.2003 10456.58114 11647.30629 11153.99082 9591.591747 10917.14617 13990.82746 10062.28791 10341.49771 1.084147051 1.020471174 1.011128314 1.126268808 1.07856629 0.927485749 1.055663936 1.352882132 0.973001029 1 13.33615752 -4.26499302 5.545464116 1.038537584 1.363437631 0.752600399 0.055322558 0.052103464 6.290878427 0.007465988 0.063917195 5.43E-05 4.26499302 0.324900047 EGQPSPADEKGNDS(ph)DGEGESDDPEKKK ddPTM_HeLa_Curcumin_4h_R1 1 EGQPSPADEKGNDSDGEGESDDPEKKK 27 3 O75351;K7EKZ3 O75351 VPS4B Vacuolar protein sorting-associated protein 4B 1 0 EGQPS(0.011)PADEKGNDS(0.911)DGEGES(0.077)DDPEKKK 56.681 0.0023981 19038000 6535.9 5053.8 4607.8 5326.7 4877.2 5489.8 4767 4912.4 5571.5 4801.3 TRUE FALSE FALSE 6018.576618 5490.627953 4778.569121 5304.659527 4819.042575 4351.153597 4900.74919 6410.168146 4960.320389 4968.144818 1.21143341 1.105166648 0.961841753 1.067734481 0.969988346 0.87581054 0.986434448 1.290253884 0.99842508 1 12.27849151 -6.786477474 24.11232893 1.103032562 1.016189012 0.028324896 0.116945202 277.6463294 267379.3568 0.020304148 0.026692407 1.64E-07 6.786477474 -0.08684355 EGQPSPADEKGNDSDGEGES(ph)DDPEK ddPTM_HeLa_Curcumin_4h_R1 1 EGQPSPADEKGNDSDGEGESDDPEK 25 1 O75351;K7EKZ3 O75351 VPS4B Vacuolar protein sorting-associated protein 4B 1 0 EGQPSPADEKGNDS(0.313)DGEGES(0.687)DDPEK 79.365 7.26E-05 102540000 4639.7 4143.2 5280.5 4662 5025.7 5065.5 4697.7 3559.1 3911.4 4209.2 TRUE FALSE FALSE 4272.462849 4501.319746 5476.199975 4642.709879 4965.77181 4014.8582 4829.504819 4644.253206 3482.329206 4355.469387 0.980942 1.033486714 1.257315685 1.065949377 1.140123226 0.921796905 1.108836819 1.066303719 0.799530176 1 12.08861249 -6.994080864 24.99690271 0.991853748 1.09202024 0.305287477 0.098696543 153.6017724 648666.1519 0.012162411 0.01595979 1.01E-07 6.994080864 0.100166493 EGRGES(ph)ENAGTNQETR ddPTM_HeLa_Curcumin_4h_R1 3 EGRGESENAGTNQETR 16 1 Q08170 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 1 0 EGRGES(0.976)ENAGT(0.024)NQETR;EGRGES(0.992)ENAGT(0.008)NQETR;EGRGES(0.733)ENAGT(0.267)NQETR ;; 218.64 2.43E-14 137776000 5305 4158.2 4586 4441.32 4240.1 5223.3 4100.12 3006.51 5316.4 4683.1 TRUE FALSE FALSE 4885.103652 4517.616279 4755.961194 4422.942995 4189.539577 4139.928701 4215.158332 3923.181059 4733.204221 4845.837376 1.008103094 0.932267414 0.98145291 0.912730381 0.864564626 0.854326792 0.869851381 0.809598167 0.97675672 1 12.24253027 -6.06104964 0.745664018 1.004624427 0.830913067 0.871143203 0.023660062 0.137882979 0.145958284 0.004140213 0.012051663 8.69E-07 6.06104964 -0.17371136 EGRGESENAGTNQETR ddPTM_HeLa_Curcumin_4h_R1 1 EGRGESENAGTNQETR 16 1 Q08170 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 0 0 89.311 0.0084641 383160 0 0 0 0 0 0 0 0 96.942 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 86.30770514 0 0 ASHGYGGK(ac)FGVEQDR ddPTM_HeLa_Curcumin_4h_R1 2 ASHGYGGKFGVEQDR 15 1 Q14247;Q14247-3;Q14247-2 Q14247 CTTN Src substrate cortactin 0 1 ; ASHGYGGK(1)FGVEQDR;ASHGYGGK(1)FGVEQDR 168.05 0.00022057 22529000 3394.5 3069.6 2397.9 2728.9 2831.3 3884 3761.2 13535.6 2942.6 2356.05 FALSE TRUE FALSE 3125.821743 3334.922546 2486.768283 2717.608535 2797.538597 3078.414618 3866.729149 17662.54213 2619.804142 2437.922562 1.282166133 1.367936208 1.020035797 1.114723075 1.147509211 1.262720427 1.58607546 7.24491516 1.074605151 1 11.25143659 -4.258335228 4.170137954 1.157000766 7.756544281 0.996219395 0.111873968 0.011686078 0.447986268 0.020045221 0.230578673 5.52E-05 4.258335228 6.599543515 up EGRPSGEAFVELES(ph)EDEVK ddPTM_HeLa_Curcumin_4h_R1 2 EGRPSGEAFVELESEDEVK 19 1 P31943;G8JLB6;E9PCY7;D6RBM0;D6RIH9;D6RAM1;D6R9T0;D6RFM3;D6RIT2;D6RIU0;D6RDU3;D6RJ04;E7EN40;D6RDL0;E7EQJ0 P31943;E7EQJ0 HNRNPH1 "Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed" 1 0 EGRPSGEAFVELES(1)EDEVK;EGRPSGEAFVELES(1)EDEVK ; 136.64 7.02E-05 66009000 6152.2 5028.7 5704.8 5391.2 6448.1 6990.8 6646 7563.5 5686.7 5186.9 TRUE FALSE FALSE 5665.246878 5463.358421 5916.224906 5368.892643 6371.210619 5540.829277 6832.468873 9869.576332 5062.883237 5367.144389 1.055542104 1.017926485 1.102304033 1.000325733 1.187076433 1.032360763 1.273017526 1.838887799 0.943310422 1 12.38993899 -4.144197981 1.621399474 1.038474945 2.313955162 0.935227151 0.063418996 0.200222346 0.395606131 0.007830409 0.436131002 7.17E-05 4.144197981 1.275480217 EGRPSGEAFVELES(ph)EEEVK ddPTM_HeLa_Curcumin_4h_R1 1 EGRPSGEAFVELESEEEVK 19 1 P55795 P55795 HNRNPH2 Heterogeneous nuclear ribonucleoprotein H2 1 0 EGRPSGEAFVELES(1)EEEVK 140.88 5.90E-05 3342800 1847.4 1671.6 1686.1 1667 2086.6 2704.8 1678.9 1804.4 1650.1 1848.6 TRUE FALSE FALSE 1701.176341 1816.085655 1748.588349 1660.102396 2061.718658 2143.793991 1726.005415 2354.553254 1469.088158 1912.838712 0.889346462 0.949419124 0.914132665 0.867873692 1.077831939 1.120739546 0.902326686 1.230920954 0.768014652 1 10.90149952 -5.742549728 24.79546233 0.938876346 1.07275175 0.423341896 0.09876166 179.6020089 235752.7446 0.011779682 0.023527651 1.81E-06 5.742549728 0.133875403 EGRPSGEAFVELESEDEVK ddPTM_HeLa_Curcumin_4h_R1 3 EGRPSGEAFVELESEDEVK 19 1 P31943;G8JLB6;E9PCY7;D6RBM0;D6RIH9;D6RAM1;D6R9T0;D6RFM3;D6RIT2;D6RIU0;D6RDU3;D6RJ04;E7EN40;D6RDL0;E7EQJ0 P31943;E7EQJ0 HNRNPH1 "Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed" 0 0 ;; ;; 149.47 6.52E-05 19617400 7229.35 6735.85 6538.61 7184.99 7142.99 8115.77 6550.5 5666.28 8077.46 6844.73 FALSE FALSE TRUE 6657.139319 7318.06686 6780.936639 7155.260415 7057.814509 6432.467818 6734.2894 7393.902688 7191.382847 7082.583858 0.939930886 1.033248177 0.957410004 1.010261306 0.996502781 0.9082092 0.950823814 1.043955544 1.015361483 1 12.79006006 -4.249473609 23.81359729 0.973229221 1.043955629 0.197962949 0.037544299 1067.646767 2124692.348 0.005107072 0.108016586 5.63E-05 4.249473609 0.070726408 EGS(ph)GDGGRAELNPWPEYIYTR ddPTM_HeLa_Curcumin_4h_R1 2 EGSGDGGRAELNPWPEYIYTR 21 1 P26639;P26639-2;D6RCA5;D6R9F8;D6RDJ6 P26639 TARS "Threonine--tRNA ligase, cytoplasmic" 1 0 EGS(1)GDGGRAELNPWPEYIYTR;EGS(1)GDGGRAELNPWPEYIYTR ; 65.855 0.0019535 8664000 809.18 712.15 610.143 759.56 659.47 777.89 685.05 793.89 1075.11 713.2 TRUE FALSE FALSE 745.1325492 773.7050727 632.7554363 756.417142 651.606251 616.5468454 704.2706593 1035.943406 957.1731228 737.9836469 1.009687074 1.048404089 0.857411189 1.024978189 0.882954864 0.835447842 0.954317433 1.403748458 1.297011291 1 9.527445038 -2.651634923 14.90264773 0.996869799 1.092439124 0 0.178759104 0 0 0.018327841 0 0.002230309 2.651634923 0.095569325 EGS(ph)PEPWLPLT(ph)DGRSPR ddPTM_HeLa_Curcumin_4h_R1 1 EGSPEPWLPLTDGRSPR 17 1 J3KSM5;Q494U1-3;Q494U1;Q494U1-2 J3KSM5 PLEKHN1 Pleckstrin homology domain-containing family N member 1 2 0 EGS(1)PEPWLPLT(0.515)DGRS(0.485)PR 91.166 0.0059992 1646500 1481.6 1307.8 1298.3 1500.3 1257.8 1053.7 732.06 579.22 1593.9 1322 TRUE FALSE FALSE 1364.329797 1420.840405 1346.41614 1494.092156 1242.801556 835.1507424 752.5996334 755.8215116 1419.053158 1367.939402 0.997361283 1.038672037 0.984265925 1.092221011 0.908520915 0.610517353 0.550170302 0.55252558 1.037365512 1 10.41778861 -5.294791162 2.920318182 1.006809794 0.554970967 0.974129286 0.033096488 0.025499063 0.432759176 0.004321868 0.011412465 5.07E-06 5.294791162 -0.451838827 KAEAGAGS(ph)ATEFQFR ddPTM_HeLa_Curcumin_4h_R1 2 KAEAGAGSATEFQFR 15 1 P46783;Q9NQ39 P46783 RPS10;RPS10P5 40S ribosomal protein S10;Putative 40S ribosomal protein S10-like 1 0 KAEAGAGS(0.93)AT(0.07)EFQFR;KAEAGAGS(0.821)AT(0.179)EFQFR ; 82.859 0.0063265 61716000 7106.8 6006.4 5741.5 7301.8 7156.2 8840.8 3411 2209.59 7751.9 6887 TRUE FALSE FALSE 6544.289281 6525.566452 5954.285041 7271.587086 7070.866989 7007.118424 3506.70348 2883.283819 6901.535964 7126.322737 0.918326256 0.915698979 0.835534014 1.020384195 0.992218182 0.983272675 0.492077557 0.404596301 0.968456835 1 12.79894211 -4.727516339 5.421039339 0.956356644 0.433644031 0.935489623 0.053225319 0.031665328 2.350928773 0.008081323 0.030334673 1.87E-05 4.727516339 -0.522712614 down EGS(ph)PIPHDPEFGSK ddPTM_HeLa_Curcumin_4h_R1 4 EGSPIPHDPEFGSK 14 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 0 EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK;EGS(1)PIPHDPEFGSK ;;; 144.15 0.00031277 1442380000 49214 42477.2 44723.4 39751.1 51037 49230 40373 26644.6 47678 37579.6 TRUE FALSE FALSE 45318.65997 46148.73989 46380.88855 39586.62048 50428.41711 39019.14306 41505.75772 34768.41588 42447.84268 38885.4883 1.165438881 1.18678566 1.192755719 1.01803069 1.296844126 1.003437137 1.067384249 0.894123165 1.091611409 1 15.24694424 -5.042337417 24.99993736 1.106648184 0.994417523 0.310287051 0.093969924 572.9991703 338351.4252 0.014640726 0.037330296 9.07E-06 5.042337417 -0.11223066 EGS(ph)QGELTPANSQSR ddPTM_HeLa_Curcumin_4h_R1 3 EGSQGELTPANSQSR 15 0 J3QQX0;C9JFE4;A0A096LP07;A0A096LPJ3;A8K070;Q13098-5;Q13098;Q13098-7 J3QQX0 GPS1 COP9 signalosome complex subunit 1 1 0 EGS(0.999)QGELT(0.001)PANSQSR;EGS(0.877)QGELT(0.123)PANSQSR;EGS(0.997)QGELT(0.003)PANSQSR ;; 142.4 0.00051702 57775300 4526.2 4506.7 4611.5 4361 4564.3 4514.6 3999.2 4647.5 4411 4315.07 TRUE FALSE FALSE 4167.946494 4896.239067 4782.406247 4342.955338 4509.873704 3578.22107 4111.406789 6064.501356 3927.124336 4465.018361 0.933466821 1.096577588 1.071083221 0.972662369 1.010045948 0.801390001 0.920804005 1.358225401 0.879531509 1 12.12445039 -4.256673523 24.77273574 0.972864187 1.358225581 0.666147927 0.083335269 198.6552842 1032561.909 0.011136941 0.120395423 5.54E-05 4.256673523 0.385361394 EGSEFSFS(ph)DGEVAEKAEVYGSENESER ddPTM_HeLa_Curcumin_4h_R1 1 EGSEFSFSDGEVAEKAEVYGSENESER 27 1 Q9BVS4;Q9BVS4-2 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 0 EGS(0.022)EFS(0.303)FS(0.672)DGEVAEKAEVY(0.002)GSENESER 44.815 0.01555 3424500 493.13 194.86 376.03 232.15 311.63 614.84 496 188.97 453.78 442.54 TRUE FALSE FALSE 454.0982402 211.7028301 389.9660026 231.1894248 307.9140158 487.3152533 509.9164251 246.5860831 404.0014693 457.9182321 0.991657917 0.462315792 0.851606194 0.504870539 0.672421394 1.064197097 1.113553446 0.5384937 0.88225679 1 8.838946197 -7.455132001 24.99875889 0.996321093 0.760106858 0.166833844 0.211994793 202.6549253 74780.31924 0.035754149 0.040885132 3.51E-08 7.455132001 -0.236214235 EGSGSSGTGEQKEDQKEEK(ac)Q ddPTM_HeLa_Curcumin_4h_R1 2 EGSGSSGTGEQKEDQKEEKQ 20 3 P38646 P38646 HSPA9 "Stress-70 protein, mitochondrial" 0 1 ; EGSGSSGTGEQKEDQK(0.004)EEK(0.996)Q;EGSGSSGTGEQKEDQK(0.005)EEK(0.995)Q 132.25 6.39E-06 7664900 1650.45 2365.84 1329.47 1700.63 3089.31 4889 2951.02 2457.23 3768.99 1471.81 FALSE TRUE FALSE 1519.815141 2570.332668 1378.741328 1693.593244 3052.471996 3874.96629 3033.817679 3206.428115 3355.541227 1522.955288 0.997938123 1.68772694 0.905306504 1.112043969 2.004308347 2.544372983 1.992059585 2.105398721 2.203309088 1 10.57265787 -5.726537911 4.095183311 1.052403654 2.201907186 0.405858608 0.439344293 0.061952886 2.243566119 0.035915526 0.072164 1.88E-06 5.726537911 1.149503531 EGSITQGT(ph)PLKYDTGASTTGSK ddPTM_HeLa_Curcumin_4h_R1 1 EGSITQGTPLKYDTGASTTGSK 22 1 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 EGS(0.012)IT(0.041)QGT(0.929)PLKY(0.001)DT(0.002)GAS(0.01)T(0.002)T(0.002)GS(0.001)K 72.755 0.001603 13835000 1005.5 673.29 806.33 837.55 1057.6 1287.1 1346.6 773.01 1081.1 864.14 TRUE FALSE FALSE 925.913614 731.4861875 836.2132991 834.08444 1044.988811 1020.140951 1384.381972 1008.69719 962.5060348 894.1688007 1.035502036 0.818062749 0.935185055 0.93280423 1.168670625 1.140881845 1.548233366 1.128083634 1.076425429 1 9.804403398 -5.308427908 1.894992301 0.990044773 1.327199357 0.54283141 0.126988738 0.184256905 1.265232812 0.017281869 0.053570756 4.92E-06 5.308427908 0.337154583 EGSQGELT(ph)PANSQSR ddPTM_HeLa_Curcumin_4h_R1 2 EGSQGELTPANSQSR 15 0 J3QQX0;C9JFE4;A0A096LP07;A0A096LPJ3;A8K070;Q13098-5;Q13098;Q13098-7 J3QQX0 GPS1 COP9 signalosome complex subunit 1 1 0 EGSQGELT(1)PANSQSR;EGSQGELT(0.999)PANS(0.001)QSR ; 144.17 0.0014495 148253000 4497.7 4073.8 4223.6 3911.3 4435.2 5271.6 5019.7 2672 4618.9 4091.3 TRUE FALSE FALSE 4141.702299 4425.921119 4380.130331 3895.116077 4382.313137 4178.210737 5160.539272 3486.6805 4112.218226 4233.47237 0.978322742 1.045458841 1.034642475 0.920075941 1.035158081 0.9869465 1.218984989 0.823598265 0.971358229 1 12.04762576 S(ph)LPAGDALYLSFNPPQPSR ddPTM_HeLa_Curcumin_4h_R1 2 SLPAGDALYLSFNPPQPSR 19 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF0 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 0 S(0.999)LPAGDALYLSFNPPQPS(0.001)R;S(0.999)LPAGDALYLS(0.001)FNPPQPSR ; 92.679 0.0016606 70258000 1180.78 1357.98 1130.51 1087.79 1291.19 1835.53 1905.68 2240.34 1520.14 1320.12 TRUE FALSE FALSE 1087.320017 1475.35774 1172.407695 1083.289013 1275.793403 1454.820387 1959.148252 2923.409353 1353.384445 1365.994072 0.795991754 1.080061598 0.858281686 0.793040787 0.933967013 1.065026868 1.434228956 2.140133265 0.990768901 1 10.41573551 -4.268775115 1.358987349 0.903746109 2.665816348 0.948934798 0.087196937 0.2103877 0.3372576 0.014354386 0.506497878 5.39E-05 4.268775115 1.762070239 up GLNPDGTPALSTLGGFSPASKPS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 GLNPDGTPALSTLGGFSPASKPSSPR 26 1 Q9UK58-6;Q9UK58 Q9UK58-6 CCNL1 Cyclin-L1 1 0 GLNPDGTPALSTLGGFSPAS(0.013)KPS(0.586)S(0.401)PR;GLNPDGTPALSTLGGFSPAS(0.075)KPS(0.573)S(0.351)PR ; 140.84 1.79E-08 219420000 5030 4232.9 3956.7 4039.6 4151.2 4978.2 5049.1 7327.3 4577.3 4198.6 TRUE FALSE FALSE 4631.870192 4598.773015 4103.338783 4022.885206 4101.699651 3945.665204 5190.764157 9561.360039 4075.181642 4344.501037 1.066145491 1.058527314 0.94449023 0.925971745 0.944112941 0.908197551 1.194789485 2.200795893 0.938009131 1 12.08497478 -4.268271551 3.231484653 1.007657804 2.361597118 0.973163538 0.060681927 0.039248827 0.649318338 0.009231777 0.131699121 5.39E-05 4.268271551 1.353939314 up EGT(ph)GQQERESPRPLQLPGAEGPAIS(ph)DGEEGGGEPGAGGGAAGAAGAGR ddPTM_HeLa_Curcumin_4h_R1 1 EGTGQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR 48 2 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 2 0 EGT(0.51)GQQERES(0.491)PRPLQLPGAEGPAIS(0.999)DGEEGGGEPGAGGGAAGAAGAGR 56.769 8.80E-06 15470000 291.93 339.9 324.2 288.04 290.38 292.5 273.38 0 203.75 268.81 TRUE FALSE FALSE 268.8234325 369.2794414 336.2151372 286.8481668 286.9174082 231.8322028 281.050307 0 181.3991348 278.1511275 0.96646537 1.327621587 1.208749863 1.031267316 1.031516251 0.83347569 1.010423037 0 0.652160343 1 8.119725143 -4.262369913 8.681673453 1.019492692 1.12E-15 0.749905913 0.17430232 0.023966697 31.62237205 0.019092258 0.147040805 5.47E-05 4.262369913 -1.019492692 EGT(ph)GQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR ddPTM_HeLa_Curcumin_4h_R1 1 EGTGQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR 48 2 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 1 0 EGT(0.494)GQQERES(0.494)PRPLQLPGAEGPAIS(0.013)DGEEGGGEPGAGGGAAGAAGAGR 45.746 0.0026175 22018000 509.87 532.72 657.04 633 718.04 1035.4 783.2 367.2 473.52 511.79 TRUE FALSE FALSE 469.5132515 578.765943 681.3904804 630.3808137 709.477842 820.6463686 805.1744841 479.1575896 421.5760407 529.5746644 0.886585562 1.092888278 1.286674998 1.190353044 1.339712584 1.549632986 1.520417305 0.904797042 0.79606535 1 9.048690293 -6.858801369 2.12153048 0.946018705 1.326069079 0.504049472 0.177225592 0.186198307 1.708899462 0.028691601 0.039513349 1.38E-07 6.858801369 0.380050374 EGTAPS(ph)ENGETK ddPTM_HeLa_Curcumin_4h_R1 4 EGTAPSENGETK 12 0 Q15651;A0A087WZE9 Q15651 HMGN3 High mobility group nucleosome-binding domain-containing protein 3 1 0 EGT(0.002)APS(0.937)ENGET(0.061)K;EGT(0.005)APS(0.987)ENGET(0.008)K;EGT(0.043)APS(0.957)ENGETK;EGT(0.004)APS(0.996)ENGETK ;;; 206.45 4.64E-09 65192000 15354.1 13134.7 18146.4 15661.4 20920.5 18032.8 18053.7 17289.6 15389.6 15267 TRUE FALSE FALSE 14138.80678 14270.00494 18818.92155 15596.59728 20671.0367 14292.59401 18560.23823 22561.11945 13701.39938 15797.52711 0.895001267 0.903306248 1.19125743 0.987280931 1.308498258 0.904736159 1.174882505 1.428142474 0.867312921 1 13.94741112 -1 0.399400993 0.956006162 7.813855881 0.495787529 0.132699817 38.67575274 0.457177399 0.031130366 210.9254826 0.1 1 6.857849719 EGTETFADHR ddPTM_HeLa_Curcumin_4h_R1 4 EGTETFADHR 10 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 ;;; ;;; 167.09 0.00012399 67741400 21295.9 18277.2 18067.8 19471.6 20938.7 24840.9 18479.3 17453.3 21579.3 18253.2 FALSE FALSE TRUE 19610.30704 19856.99973 18737.40856 19391.03168 20689.01968 19688.61733 18997.77942 22774.73082 19212.10478 18887.49734 1.038269215 1.051330378 0.992053538 1.026659664 1.095381739 1.042415359 1.005838893 1.205809876 1.017186366 1 14.20514393 -4.257605644 24.98513705 1.025628754 1.205809946 0.771148681 0.028663093 138.7669694 904330.5658 0.0042708 0.042369348 5.53E-05 4.257605644 0.180181192 EGTGQQERES(ph)PRPLQLPGAEGPAIS(ph)DGEEGGGEPGAGGGAAGAAGAGR ddPTM_HeLa_Curcumin_4h_R1 1 EGTGQQERESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR 48 2 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 2 0 EGT(0.464)GQQERES(0.538)PRPLQLPGAEGPAIS(0.998)DGEEGGGEPGAGGGAAGAAGAGR 48.515 0.0017055 15404000 288.27 193.73 299.87 0 304.94 460.63 128.87 203.45 180.38 219.69 TRUE FALSE FALSE 265.4531253 210.475158 310.983446 0 301.3037897 365.0901456 132.4857454 265.4809684 160.5927653 227.3242111 1.167729227 0.925880956 1.368017267 0 1.325436425 1.606032828 0.582805257 1.167851709 0.706448136 1 7.828607536 EGTGSTATSSS(ph)STAGAAGK ddPTM_HeLa_Curcumin_4h_R1 1 EGTGSTATSSSSTAGAAGK 19 0 E5RHC7;E5RH59;E5RFW7;E5RFH0;E5RGU4;A0A087WZK9;B3KS98;O15372 E5RHC7 EIF3H Eukaryotic translation initiation factor 3 subunit H 1 0 EGTGSTAT(0.074)S(0.211)S(0.211)S(0.448)S(0.055)TAGAAGK 172.42 3.58E-06 14399000 4914.4 4216.1 4589.7 5488.1 5009.1 7410.5 5939.8 4454.7 4994 5593.7 TRUE FALSE FALSE 4525.420054 4580.520897 4759.79832 5465.391696 4949.369754 5873.478766 6106.454802 5812.917523 4446.170694 5788.080659 0.781851588 0.791371297 0.82234485 0.944249401 0.855096887 1.014754132 1.055005132 1.004291036 0.768159768 1 12.49886931 -5.215333757 6.279971529 0.882130169 1.029209403 0.506767915 0.074018936 0.195850744 19.824737 0.013111855 0.033572374 6.09E-06 5.215333757 0.147079234 EGTGSTATSSSS(ph)TAGAAGK ddPTM_HeLa_Curcumin_4h_R1 1 EGTGSTATSSSSTAGAAGK 19 0 E5RHC7;E5RH59;E5RFW7;E5RFH0;E5RGU4;A0A087WZK9;B3KS98;O15372 E5RHC7 EIF3H Eukaryotic translation initiation factor 3 subunit H 1 0 EGTGSTATS(0.002)SS(0.116)S(0.879)T(0.002)AGAAGK 384.6 2.28E-253 11950000 3525.2 3393.2 3256.9 4142.5 3326.4 5176.9 4912.8 3421.7 3803.7 3876.9 TRUE FALSE FALSE 3246.1767 3686.493088 3377.603579 4125.359433 3286.734853 4103.152584 5050.639946 4464.960578 3386.443626 4011.621986 0.809193067 0.918953256 0.841954599 1.028351985 0.81930323 1.022816357 1.259001961 1.113006309 0.844158208 1 11.96996995 -4.966457414 4.84825468 0.907481548 1.182128482 0.690478679 0.077547234 0.089206958 5.125213463 0.012112736 0.037202053 1.08E-05 4.966457414 0.274646935 EGTGSTATSSSSTAGAAGK ddPTM_HeLa_Curcumin_4h_R1 2 EGTGSTATSSSSTAGAAGK 19 0 E5RHC7;E5RH59;E5RFW7;E5RFH0;E5RGU4;A0A087WZK9;B3KS98;O15372 E5RHC7 EIF3H Eukaryotic translation initiation factor 3 subunit H 0 0 ; ; 430.07 0 2963500 738.24 757.76 556.55 471.05 471.57 788.01 483.54 585.63 516.17 702.99 FALSE FALSE TRUE 679.807525 823.2573979 577.1762326 469.1009199 465.9468357 624.5678433 497.106831 764.1858911 459.5474424 727.4188502 0.934547579 1.131751532 0.793457899 0.644884195 0.640548201 0.858608274 0.683384588 1.050544526 0.631750803 1 9.506642502 -6.619976493 8.382213368 0.980235864 0.762851399 0.122070505 0.165544258 0.177698623 13.72094447 0.018461866 0.026122277 2.40E-07 6.619976493 -0.217384465 EGTQASEGYFSQS(ph)QEEEFAQSEELCAK ddPTM_HeLa_Curcumin_4h_R1 2 EGTQASEGYFSQSQEEEFAQSEELCAK 27 0 Q16643-3;Q16643;Q16643-2 Q16643-3 DBN1 Drebrin 1 0 EGTQASEGYFSQS(1)QEEEFAQSEELCAK;EGTQASEGYFS(0.005)QS(0.994)QEEEFAQS(0.001)EELCAK ; 141.29 3.02E-09 28660000 7857.3 6157.9 6688.5 7989 7128.1 9390.9 6498.5 7458.8 8279.8 6273.9 TRUE FALSE FALSE 7235.386414 6690.161437 6936.381694 7955.943635 7043.102063 7443.121483 6680.83042 9732.953784 7371.526655 6491.917558 1.114522227 1.03053703 1.06846423 1.225515199 1.084903189 1.146521258 1.029099701 1.499241741 1.135492956 1 12.66442896 -4.257852525 24.94977907 1.072874378 1.499241908 0.769123399 0.066001676 123.453308 858689.2286 0.009790291 0.097177694 5.52E-05 4.257852525 0.42636753 EGVFAK(ac)EVR ddPTM_HeLa_Curcumin_4h_R1 1 EGVFAKEVR 9 1 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 1 EGVFAK(1)EVR 101.97 0.0074755 55955000 3903.5 3274.3 3884 3848.2 3779 3040.6 2931.4 2770.3 4205.7 3541.5 FALSE TRUE FALSE 3594.533856 3557.315902 4027.944457 3832.277168 3733.937893 2409.945285 3013.647195 3614.951717 3744.345232 3664.566861 0.980889145 0.970732978 1.099159767 1.045765383 1.018930213 0.657634415 0.822374733 0.986460843 1.021770205 1 11.83942697 -5.301893495 24.98575621 1.003373628 0.822178385 0.543568584 0.08197459 286.338636 176851.4612 0.011380627 0.02544813 4.99E-06 5.301893495 -0.181195243 EGVHGGLINK ddPTM_HeLa_Curcumin_4h_R1 4 EGVHGGLINK 10 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 0 ;;; ;;; 103.26 0.0027094 62962000 20155.9 17499 18522 18752 20996.7 22075.6 19135 17423.8 18886.2 16232.2 FALSE FALSE TRUE 18560.53925 19011.53559 19208.44161 18674.40919 20746.32807 17496.87172 19671.8766 22736.23641 16814.43111 16796.26774 1.105039496 1.131890482 1.143613683 1.111818975 1.235174884 1.041711884 1.171205229 1.353648129 1.001081393 1 14.03585307 -1.000000001 0.071686295 0.828588813 1.878299266 0.570524945 0.067227212 124.3287608 0.663236332 1.693607405 13.19211644 0.1 1.000000001 1.049710453 EGVHGGLINK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EGVHGGLINKK 11 1 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 1 ; EGVHGGLINK(1)K;EGVHGGLINK(1)K 136.49 7.59E-05 203720000 14531.8 20666.6 14264.5 12710.1 27813 40498 30404 26534 39307 15260.4 FALSE TRUE FALSE 13381.5927 22452.92882 14793.15492 12657.50897 27481.34814 32098.25829 31257.05441 34624.09445 34995.12044 15790.69776 0.847435173 1.421908591 0.936827184 0.801580092 1.740350461 2.032732104 1.979459988 2.192689327 2.216185818 1 13.9467873 -5.627888666 3.837283168 0.960481428 2.040580919 0.38631505 0.432510139 0.051619882 1.436382233 0.026181173 0.054626582 2.36E-06 5.627888666 1.080099491 EGVILTNESAAS(ph)TGQPDNDVTEGQR ddPTM_HeLa_Curcumin_4h_R1 1 EGVILTNESAASTGQPDNDVTEGQR 25 0 Q08J23-2;Q08J23;Q08J23-3 Q08J23-2 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 0 EGVILTNES(0.012)AAS(0.645)T(0.343)GQPDNDVTEGQR 82.986 0.00010058 0 921.97 746.38 903.94 830.24 929.41 1151 916.73 1396.3 971.7 993.08 TRUE FALSE FALSE 848.9951016 810.8937614 937.4408116 826.8046869 918.3273928 912.2696256 942.4509765 1822.025442 865.1069411 1027.589456 0.826200674 0.789122306 0.912271731 0.804606044 0.893671483 0.887776359 0.917147379 1.773106401 0.841879932 1 10.00504828 -4.261360038 6.11349982 0.895450427 1.795267686 0.949439584 0.062048299 0.025276316 4.75611109 0.01098828 0.09392323 5.48E-05 4.261360038 0.89981726 EVQQK(ac)IEK ddPTM_HeLa_Curcumin_4h_R1 1 EVQQKIEK 8 1 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 1 EVQQK(1)IEK 171.56 1.73E-09 5492200 2433.9 1952.6 1713.8 2063.7 2133.5 2524.5 2329.7 3246.9 2112.7 1901.2 FALSE TRUE FALSE 2241.254247 2121.374043 1777.314936 2055.160956 2108.059406 2000.890243 2395.065112 4236.864863 1880.942096 1967.266558 1.139273291 1.078335843 0.903443882 1.044678438 1.071567753 1.017091575 1.217458357 2.153681129 0.95611959 1 10.94197674 -4.257130444 3.052189098 1.053175771 2.334655696 0.961600621 0.067093631 0.053391845 0.729303228 0.009976845 0.16572895 5.53E-05 4.257130444 1.281479925 up EGVKFDESEK(ac)TK ddPTM_HeLa_Curcumin_4h_R1 2 EGVKFDESEKTK 12 2 P14625 P14625 HSP90B1 Endoplasmin 0 1 ; EGVKFDESEK(1)TK;EGVKFDESEK(1)TK 102.9 0.0014386 4911600 2515.3 2722 1917.02 2192.1 2536.3 5261.6 3153.9 2161.6 6034.5 2571.5 FALSE TRUE FALSE 2316.211351 2957.277551 1988.066448 2183.029671 2506.056279 4170.28485 3242.389946 2820.661889 5372.530448 2660.859434 0.870474901 1.11139939 0.747152 0.820422771 0.941822122 1.567269882 1.218549881 1.060056707 2.019095928 1 11.37767658 -5.384814781 10.03224078 0.926576763 1.275309204 0 0.376109604 0.218846757 16.86457971 0.020873422 0.046706639 4.12E-06 5.384814781 0.348732441 EGVNQPAAVVMEDS(ph)SPHEALR ddPTM_HeLa_Curcumin_4h_R1 3 EGVNQPAAVVMEDSSPHEALR 21 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 EGVNQPAAVVMEDS(0.5)S(0.5)PHEALR;EGVNQPAAVVMEDS(0.5)S(0.5)PHEALR;EGVNQPAAVVMEDS(0.5)S(0.5)PHEALR ;; 92.41 0.00024434 66539600 13365.8 10968 12686.2 13582.4 14044.3 19712.5 15208.4 7405.93 13934.8 11080.5 TRUE FALSE FALSE 12307.88283 11916.02505 13156.36173 13526.19963 13876.8309 15623.90529 15635.10677 9663.963964 12406.1873 11465.54655 1.073466736 1.039289753 1.147469218 1.179725674 1.210306969 1.362682993 1.363659962 0.84286989 1.082040638 1 13.48501751 -6.575046987 1.478586914 1.032928502 1.216656161 0.182865363 0.13739917 0.383314623 1.68472334 0.022450235 0.036038149 2.66E-07 6.575046987 0.183727659 EGVQGPLNVS(ph)LSEEGK ddPTM_HeLa_Curcumin_4h_R1 3 EGVQGPLNVSLSEEGK 16 0 P12270 P12270 TPR Nucleoprotein TPR 1 0 EGVQGPLNVS(0.973)LS(0.027)EEGK;EGVQGPLNVS(0.538)LS(0.462)EEGK;EGVQGPLNVS(1)LSEEGK ;; 258.8 1.48E-40 68133000 9905.9 8446.2 10752.3 9802.7 11421.3 12474 10352.3 6000.4 8540 8098.3 TRUE FALSE FALSE 9121.837562 9176.251892 11150.7897 9762.139025 11285.10846 9886.751789 10642.75768 7829.894338 7603.183366 8379.715322 1.088561748 1.095055326 1.330688367 1.164972633 1.346717403 1.179843397 1.270061961 0.934386675 0.907331941 1 13.03268552 -7.288278813 1.502787049 1.03303743 1.208982914 0.358809933 0.118287969 0.310577092 1.337999008 0.020480209 0.024043404 5.15E-08 7.288278813 0.175945483 EGVQGPLNVS(ph)LSEEGKSQEQILEILR ddPTM_HeLa_Curcumin_4h_R1 1 EGVQGPLNVSLSEEGKSQEQILEILR 26 1 P12270 P12270 TPR Nucleoprotein TPR 1 0 EGVQGPLNVS(0.765)LS(0.234)EEGKS(0.001)QEQILEILR 58.913 0.0020981 3806300 1343.2 1006.3 1184.2 1007.3 816.64 1613.4 1035.1 767.5 1499.7 1289.8 TRUE FALSE FALSE 1236.884303 1093.280088 1228.087494 1003.132059 806.9021014 1278.762653 1064.14212 1001.507217 1335.186662 1334.620454 0.92676858 0.819169289 0.920177336 0.751623472 0.604592938 0.958147052 0.797336889 0.750406015 1.000424247 1 10.3822138 -7.24902846 0.783034269 0.982899179 0.780919084 0.471144382 0.089393895 0.367502246 0.462660738 0.022112843 0.026533545 5.64E-08 7.24902846 -0.201980095 EGVSSTT(ph)PAKDAASAGLGSIGVK ddPTM_HeLa_Curcumin_4h_R1 1 EGVSSTTPAKDAASAGLGSIGVK 23 1 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 1 0 EGVS(0.062)S(0.181)T(0.181)T(0.563)PAKDAAS(0.014)AGLGSIGVK 55.988 0.0094517 26948000 958.72 871.36 981.81 1209.7 811.31 1532.1 1122.3 244.58 1251 711.02 TRUE FALSE FALSE 882.8363004 946.6764757 1018.196742 1204.694582 801.6356581 1214.32519 1153.788717 319.1513161 1113.76843 735.7278921 1.199949478 1.286720928 1.383931143 1.637418664 1.089581715 1.650508568 1.568227506 0.433789883 1.513832005 1 9.523028476 -8.057371626 0.869366016 1.033750535 1.324552531 0 0.36772549 0.801841623 1.303440068 0.099564399 0.072810568 8.76E-09 8.057371626 0.290801996 EGVTPWAS(ph)FK ddPTM_HeLa_Curcumin_4h_R1 1 EGVTPWASFK 10 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 EGVT(0.016)PWAS(0.984)FK 105.2 0.0096717 42383000 3600 2828.1 3614.7 3663.1 3287.4 4920.1 5103.1 2255.5 3083.1 3321.3 TRUE FALSE FALSE 3315.056201 3072.548362 3748.663962 3647.943063 3248.199902 3899.615799 5246.279252 2943.191567 2744.891644 3436.714928 0.964600286 0.894036435 1.09076954 1.061462222 0.945146738 1.134692833 1.526538966 0.856396771 0.798696343 1 11.74681447 -5.058855129 6.058857317 0.989352284 1.224159539 0.228110361 0.170502062 0.177272297 13.76846261 0.019728094 0.05202778 8.73E-06 5.058855129 0.234807254 SIPAGAEPGEK(ac)GSAR ddPTM_HeLa_Curcumin_4h_R1 2 SIPAGAEPGEKGSAR 15 1 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 0 1 ; SIPAGAEPGEK(1)GSAR;SIPAGAEPGEK(1)GSAR 217.46 1.46E-26 20679500 1394.2 1128.53 1238.25 1137.35 1176.4 1617.75 1308.46 1977.9 1248.6 1190.21 FALSE TRUE FALSE 1283.847599 1226.075105 1284.140634 1132.643947 1162.372198 1282.210414 1345.171866 2580.952605 1111.631704 1231.569709 1.042448178 0.995538536 1.042686114 0.919675061 0.943813566 1.04111883 1.09224176 2.095660998 0.90261371 1 10.26628257 -4.256795215 3.986149085 1.009987738 2.199039675 0.975347244 0.052491694 0.021557575 0.701936918 0.00608155 0.074284531 5.54E-05 4.256795215 1.189051936 up EGVVECSFVK ddPTM_HeLa_Curcumin_4h_R1 2 EGVVECSFVK 10 0 P40926;P40926-2;G3XAL0 P40926 MDH2 "Malate dehydrogenase, mitochondrial;Malate dehydrogenase" 0 0 ; ; 163.16 2.39E-09 6376200 3730 2731.4 3224.3 3376.9 3608.3 4883.4 3725.4 3475.3 3652.3 2756.3 FALSE FALSE TRUE 3434.766564 2967.490045 3343.795394 3362.927283 3565.273379 3870.527793 3829.924698 4534.902972 3251.651828 2852.08122 1.204301806 1.040464775 1.17240539 1.179113434 1.250060256 1.35708891 1.342852606 1.5900329 1.140097906 1 11.47779935 -1 0.262557306 1.054566595 4.435771372 0.854602747 0.061759349 13.97359428 0.176325238 0.035213878 21.47939381 0.1 1 3.381204777 GFGGK(ac)FGVQTDR ddPTM_HeLa_Curcumin_4h_R1 2 GFGGKFGVQTDR 12 1 Q14247;Q14247-3;Q14247-2 Q14247 CTTN Src substrate cortactin 0 1 ; GFGGK(1)FGVQTDR;GFGGK(1)FGVQTDR 142.08 0.00010813 17584900 2371.8 1953.55 1846.74 1881.25 1959 3308.3 2751.6 9689.6 2505.4 1810.77 FALSE TRUE FALSE 2184.069527 2122.406157 1915.181809 1873.465886 1935.640204 2622.121288 2828.80249 12643.91443 2230.563888 1873.694123 1.165648918 1.132738867 1.022142187 0.999878189 1.033060936 1.399439351 1.509746151 6.748120881 1.190463193 1 10.87166974 -4.2545892 3.914837219 1.095365835 7.322047523 0.995069978 0.118238202 0.013604504 0.41430645 0.019110854 0.242919487 5.56E-05 4.2545892 6.226681688 up EGYAWAEDKEHCEEYGR ddPTM_HeLa_Curcumin_4h_R1 1 EGYAWAEDKEHCEEYGR 17 1 Q9Y3I0 Q9Y3I0 RTCB tRNA-splicing ligase RtcB homolog 0 0 108.63 0.00058574 41218000 3177.8 2163.1 2691.9 2985 2813.9 3946.2 2648.4 2690.6 2946 2583.2 FALSE FALSE TRUE 2926.273777 2350.068725 2791.664182 2972.648861 2780.34608 3127.713637 2722.706976 3510.951554 2622.831171 2672.966008 1.094766551 0.879198882 1.044406915 1.112116223 1.040172629 1.170128475 1.018608904 1.313504004 0.981243743 1 11.38422578 -1.132482999 1.009261888 1.040206193 199.9990622 0.521294589 0.077313442 835.6902743 1.40300781 0.011376872 384150.5859 0.073708403 1.132482999 198.958856 EGYK(ac)FYPPK ddPTM_HeLa_Curcumin_4h_R1 1 EGYKFYPPK 9 1 E9PBS1;P22234;P22234-2;D6RF62 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 0 1 EGYK(1)FYPPK 98.044 0.011646 2986600 2772.9 3086.6 2501.6 2936.3 3651.1 4032.4 3362.3 3399.5 4716.1 2941.8 FALSE TRUE FALSE 2553.422039 3353.39195 2594.311497 2924.150369 3607.563017 3196.034785 3456.637089 4435.991901 4198.755629 3044.027331 0.838830195 1.10163004 0.852262879 0.96061896 1.185128327 1.049936298 1.135547324 1.45727729 1.37934229 1 11.5717656 -1 0.495489336 0.931435508 16.52001016 0.238052207 0.169160356 37.6234355 0.365437404 0.019704686 612.9798241 0.1 1 15.58857465 EHALLAYTLGVK ddPTM_HeLa_Curcumin_4h_R1 4 EHALLAYTLGVK 12 0 A0A2U3TZH3;Q05639;A0A2R8Y488;A0A2R8Y660;Q5VTE0;P68104;A0A087WV01 A0A2U3TZH3;Q5VTE0 EEF1A2;EEF1A1P5;EEF1A1 Elongation factor 1-alpha 2;Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 0 ;;; ;;; 128.08 0.00020474 45906200 18282 13582 16785.4 13275.9 12975.9 30778.2 21050.6 19940.8 15882.1 14159.6 FALSE FALSE TRUE 16834.96041 14755.96756 17407.48169 13220.96784 12821.17087 24394.45438 21641.22318 26020.65812 14139.87337 14651.64505 1.149015033 1.007120191 1.188090596 0.902353818 0.875066986 1.664963511 1.477050742 1.775954716 0.965070702 1 13.83877504 -5.253071383 24.99369504 1.051879422 1.623095812 0.852944602 0.118443211 179.14771 535080.3731 0.016607212 0.041573727 5.58E-06 5.253071383 0.571216391 EHAPLAS(ph)PVENK ddPTM_HeLa_Curcumin_4h_R1 1 EHAPLASPVENK 12 0 Q9ULJ3 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 0 EHAPLAS(1)PVENK 68.751 0.018314 11625000 1744.3 2177.1 2066.8 2638.8 2412.9 2818.2 2404.4 2658.4 2223.1 2130 TRUE FALSE FALSE 1606.236814 2365.278823 2143.397426 2627.881345 2384.127743 2233.673552 2471.860993 3468.933922 1979.231492 2204.017341 0.72877685 1.073167066 0.972495718 1.192314278 1.08171914 1.013455525 1.121525201 1.573914078 0.898010853 1 11.10591986 -1 0.432932729 0.894845107 13.07769885 0.64997334 0.123410091 36.56918062 0.408278802 0.033733839 393.0491716 0.1 1 12.18285374 EHCDT(ph)EGEADDFDPGKK ddPTM_HeLa_Curcumin_4h_R1 1 EHCDTEGEADDFDPGKK 17 1 Q9H8M2 Q9H8M2 BRD9 Bromodomain-containing protein 9 1 0 EHCDT(1)EGEADDFDPGKK 81.854 0.0061284 13663000 6313 6068.5 6238.1 6449.1 7351.1 7687.6 5499.2 3266.7 6088.5 5664.9 TRUE FALSE FALSE 5813.319389 6593.034099 6469.289474 6422.415333 7263.442934 6093.105103 5653.492752 4262.701792 5420.606783 5861.754853 0.991737037 1.124754321 1.103643812 1.095647207 1.239124309 1.039467746 0.964471032 0.727205743 0.924741296 1 12.51711692 -4.289200254 2.614495974 1.039287393 0.674255055 0.581624536 0.084622192 0.275965735 2.530188104 0.012748677 0.2134656 5.14E-05 4.289200254 -0.365032339 EHEVFQR ddPTM_HeLa_Curcumin_4h_R1 1 EHEVFQR 7 0 O60884 O60884 DNAJA2 DnaJ homolog subfamily A member 2 0 0 130.77 0.0055082 3084900 877.92 931.07 790.63 829.43 1040.4 1090 710.66 821.46 824.97 762.69 FALSE FALSE TRUE 808.4317056 1011.547542 819.9314433 825.9980384 1027.99391 863.9217132 730.599207 1071.919372 734.472855 789.1934207 1.024377148 1.281748575 1.038948655 1.046635738 1.302588038 1.094689452 0.925754305 1.358246717 0.930662669 1 9.624235119 -7.485067733 24.3473155 1.010754542 1.137877749 0.24413664 0.129574225 407.4432739 262363.8495 0.020346364 0.022801333 3.27E-08 7.485067733 0.127123207 EHEVTIFVR ddPTM_HeLa_Curcumin_4h_R1 1 EHEVTIFVR 9 0 P53396;P53396-2;P53396-3;K7EIE7 P53396 ACLY ATP-citrate synthase 0 0 123.35 0.0013063 0 2261.6 3778.1 2047.6 3729.7 5851.4 5823.1 5194.8 4937.4 5160.1 5023.3 FALSE FALSE TRUE 2082.591974 4104.662129 2123.485857 3714.26749 5781.625877 4615.32342 5340.552107 6442.790531 4594.04994 5197.859301 0.400663399 0.789683193 0.408530846 0.714576381 1.112309038 0.887927732 1.027452226 1.239508451 0.883834993 1 12.34370187 -5.778273712 12.51124384 0.690563713 1.051215486 0.463159563 0.193262587 0.692101486 512.6166027 0.036847415 0.06761147 1.67E-06 5.778273712 0.360651773 EHIEELLR ddPTM_HeLa_Curcumin_4h_R1 2 EHIEELLR 8 0 H0YMC2;B4DIH5;P61201;P61201-2 H0YMC2 COPS2 COP9 signalosome complex subunit 2 0 0 ; ; 145.16 0.00050827 6105900 9105.4 8212 7793.9 8338 9099.9 9561.5 8050.3 7877.3 7103.8 7343.8 FALSE FALSE TRUE 8384.697982 8921.808688 8082.74879 8303.499565 8991.389636 7578.33712 8276.169752 10279.05251 6324.530913 7598.996503 1.103395426 1.17407722 1.063660022 1.092710013 1.183233817 0.997281301 1.08911351 1.352685516 0.832285014 1 12.8915932 -1.000000498 0.017112235 2.29E-08 2.486710101 0.381174164 0.102188546 3556.923514 4.743836253 267.8406672 442.1767464 0.099999885 1.000000498 2.486710078 EHIYDLR ddPTM_HeLa_Curcumin_4h_R1 3 EHIYDLR 7 0 Q14677-2;Q14677;Q14677-3 Q14677-2 CLINT1 Clathrin interactor 1 0 0 ;; ;; 143.11 0.002611 23727900 17844 14639.2 15331 15219.4 16026.6 18900.2 14654.5 12739.9 16178.3 14826.7 FALSE FALSE TRUE 16431.62857 15904.54722 15899.18035 15156.42616 15835.49326 14980.08547 15065.66583 16624.23686 14403.58097 15341.92672 1.071027705 1.036672089 1.036322271 0.987908913 1.032171092 0.976414876 0.981993077 1.08358208 0.938837815 1 13.90519206 -6.304286011 23.2507323 1.034867141 1.009821607 0 0.044789531 397.8632165 215899.7232 0.005749536 0.008782695 4.96E-07 6.304286011 -0.025045534 EHLELFWSR ddPTM_HeLa_Curcumin_4h_R1 2 EHLELFWSR 9 0 A0A087WVQ6;Q00610-2;Q00610;J3KS13 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 ; ; 86.882 0.018757 43969000 12176.5 8591 9827.8 9015.3 10158.6 14183.8 10443.7 8879.8 10867.7 10081.3 FALSE FALSE TRUE 11212.71718 9333.567759 10192.02691 8977.997077 10037.46533 11241.92 10736.72211 11587.21014 9675.5405 10431.62442 1.074877384 0.894737711 0.97703162 0.860651871 0.962214984 1.077676835 1.029247381 1.110777159 0.92752002 1 13.34867621 -4.459905657 1.475483228 1.005124235 1.119243749 0.171872083 0.071508297 1.308015837 3.383784911 0.011405147 0.194651874 3.47E-05 4.459905657 0.114119514 EHMQPTHPIR ddPTM_HeLa_Curcumin_4h_R1 2 EHMQPTHPIR 10 0 P61981 P61981 YWHAG "14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed" 0 0 ; ; 130.94 0.0002383 4763100 2340.8 1976.02 2369.7 2177.24 2477.2 2733.2 2178.1 2493 2254.6 1894.1 FALSE FALSE TRUE 2155.52321 2146.818364 2457.523167 2168.231158 2447.661008 2166.30351 2239.211624 3253.104224 2007.276021 1959.919834 1.099801723 1.095360293 1.253889636 1.106285635 1.248857716 1.105302101 1.14250164 1.659814941 1.024162308 1 10.93657893 -1.859190121 1.184803923 1.082696205 200 0.778717044 0.084505129 188.7536356 0.986840994 0.014158348 101215.3899 0.013829608 1.859190121 198.9173038 EHPDAWTR ddPTM_HeLa_Curcumin_4h_R1 4 EHPDAWTR 8 0 O14980;C9IYM2;H7BZC5;F8WF71;C9IZS4;C9JQ02;C9JV99;C9J673;C9JKM9 O14980 XPO1 Exportin-1 0 0 ;;; ;;; 130.56 0.0041685 25551400 8703.4 7562.9 8331.9 8811.2 8644.4 9178.5 7519.4 6599.6 8337.1 8912.1 FALSE FALSE TRUE 8014.516706 8216.603376 8640.687543 8774.741589 8541.321176 7274.775637 7730.374127 8611.787659 7422.540988 9221.794812 0.869084259 0.890998287 0.936985448 0.951522103 0.926210282 0.788867654 0.838272189 0.93385158 0.804891145 1 13.17083185 -9.375121027 0.818170503 1.009180039 0.889338622 0 0.077145345 0.63761799 0.667143397 0.051490374 0.009898477 4.22E-10 9.375121027 -0.119841417 EHPWEVMPDLYFYRDPEEIEKEEQAAAEK ddPTM_HeLa_Curcumin_4h_R1 3 EHPWEVMPDLYFYRDPEEIEKEEQAAAEK 29 2 C9J9K3;A0A0C4DG17;P08865 C9J9K3 RPSA 40S ribosomal protein SA 0 0 ;; ;; 54.717 0.0011734 85126000 9354.3 8157 7532 8561.8 8372.5 10698.9 9069.4 8534.5 9565 9002.1 FALSE FALSE TRUE 8613.897284 8862.054733 7811.142546 8526.37354 8272.663406 8479.827539 9323.862955 11136.62976 8515.74343 9314.922305 0.924741721 0.951382571 0.838562286 0.915345642 0.888108686 0.910348714 1.00095982 1.195568723 0.914204451 1 13.18532802 -4.297030154 2.936925018 0.94210271 1.228122021 0.766675699 0.044844505 0.161849628 2.076027108 0.007609289 0.104135365 5.05E-05 4.297030154 0.286019311 EHSLQVS(ph)PSLEK ddPTM_HeLa_Curcumin_4h_R1 1 EHSLQVSPSLEK 12 0 O95235-2;O95235 O95235-2 KIF20A Kinesin-like protein KIF20A 1 0 EHSLQVS(0.985)PS(0.015)LEK 125.39 0.0014243 43205000 11559 10206 10171 10225 11414 16886 13026 4616.2 11853 9318.2 TRUE FALSE FALSE 10644.09295 11088.16116 10547.94621 10182.69166 11277.8955 13383.65326 13391.4745 6023.65813 10552.75555 9642.006756 1.103929215 1.149984795 1.093957562 1.056075972 1.169662684 1.388056822 1.388867986 0.624730752 1.094456353 1 13.23511773 -8.43061134 0.49418317 0.993875949 1.151370947 0.005232671 0.202244404 2.223953328 1.139379416 0.156717292 0.062295312 3.71E-09 8.43061134 0.157494999 RAEVLGHKT(ph)PEPAPR ddPTM_HeLa_Curcumin_4h_R1 1 RAEVLGHKTPEPAPR 15 2 Q9UHD8;Q9UHD8-5;Q9UHD8-2;Q9UHD8-7;K7ENL0;K7ER34;K7EJ51 Q9UHD8 9-Sep Septin-9 1 0 RAEVLGHKT(1)PEPAPR 79.347 0.0070913 58017000 3740.9 3421.3 3637.4 3732.3 3683.6 3337.2 2353.2 1205 3765.7 3211 TRUE FALSE FALSE 3444.803818 3717.021927 3772.205244 3716.856732 3639.675476 2645.027102 2419.224459 1572.398953 3352.612131 3322.582011 1.036785189 1.118714877 1.135323442 1.118665158 1.095435858 0.796075791 0.7281158 0.473246092 1.009038188 1 11.69808909 -4.727153259 1.475974238 1.04653016 0.473617606 0.895827761 0.066626723 0.144436841 0.490003852 0.011010551 0.093944455 1.87E-05 4.727153259 -0.572912554 down EHTALLK ddPTM_HeLa_Curcumin_4h_R1 1 EHTALLK 7 0 C9K025;P18077;F8WBS5;F8WB72 C9K025 RPL35A 60S ribosomal protein L35a 0 0 79.116 0.01544 4296900 5523 4890.6 4824.1 3608.7 4479.4 6458.8 4776.8 4728.8 5001.1 5387.4 FALSE FALSE TRUE 5085.848722 5313.321672 5002.88539 3593.768156 4425.986081 5119.172074 4910.824152 6170.589351 4452.491842 5574.611749 0.912323396 0.953128561 0.897441044 0.644666986 0.793954141 0.918301095 0.880926668 1.106909257 0.798708868 1 12.44465561 -8.164925248 0.722908467 0.989115222 0.873140066 0 0.125295525 0.897653306 1.026643303 0.045396561 0.028231631 6.84E-09 8.164925248 -0.115975157 EHVEEISELFYDAK ddPTM_HeLa_Curcumin_4h_R1 2 EHVEEISELFYDAK 14 0 Q9Y265;H7C4G5 Q9Y265 RUVBL1 RuvB-like 1 0 0 ; ; 194.12 3.42E-06 10508700 13812.2 11614.4 12119.3 11094.5 14905.8 15292.3 12215.8 11997.6 11964.9 10833.3 FALSE FALSE TRUE 12718.9498 12618.29698 12568.45192 11048.5939 14728.05807 12120.5046 12558.54247 15655.61301 10652.3804 11209.75637 1.134632134 1.125653098 1.121206519 0.985623018 1.313860675 1.081246033 1.120322517 1.396606001 0.950277602 1 13.4524673 -1 0.136558767 0.988514065 1.892021558 0.427534517 0.100666298 65.10581715 0.591658662 0.278015028 11.47262378 0.1 1 0.903507493 EHVIEALR ddPTM_HeLa_Curcumin_4h_R1 2 EHVIEALR 8 0 F8W7C6;A0A087WV22;X1WI28;P27635;H7C123;H7C2C5 F8W7C6 RPL10 60S ribosomal protein L10 0 0 ; ; 119.21 0.0068018 15127700 13028.8 9835.4 11581.5 11542.7 12641.3 13164.6 10806.2 9497.3 11133.6 10488.9 FALSE FALSE TRUE 11997.55673 10685.52815 12010.72058 11494.93937 12490.56075 10434.11356 11109.39289 12392.98305 9912.271935 10853.38849 1.105420371 0.984533831 1.10663325 1.059110652 1.150844343 0.961369214 1.023587509 1.141853814 0.913288227 1 13.40585791 -9.566357666 1.320071723 0.999720818 1.068379236 0.255315117 0.066122961 0.669536502 2.077229382 0.041259051 0.009523328 2.71E-10 9.566357666 0.068658418 EHYPVSSPS(ph)SPSPPAQPGGVSR ddPTM_HeLa_Curcumin_4h_R1 2 EHYPVSSPSSPSPPAQPGGVSR 22 0 H0YM23;O75179-6;O75179-7;O75179-2;O75179;O75179-4 H0YM23 ANKRD17 Ankyrin repeat domain-containing protein 17 1 0 EHYPVS(0.036)S(0.168)PS(0.398)S(0.398)PS(0.001)PPAQPGGVSR;EHYPVS(0.001)S(0.02)PS(0.468)S(0.468)PS(0.044)PPAQPGGVSR ; 195.53 2.99E-13 12179900 6149.4 4541.1 4635.3 5013.2 5185.8 6294.9 4083.7 3126.74 6547.5 4395.9 TRUE FALSE FALSE 5662.668501 4933.612449 4807.088296 4992.456707 5123.962722 4989.266782 4198.277631 4080.068632 5829.255631 4548.657198 1.244909927 1.084630526 1.056814811 1.097567148 1.126478101 1.096865858 0.922970769 0.8969831 1.281533292 1 12.151225 -4.753288765 4.402590581 1.110600734 0.903177022 0.531747999 0.079703981 0.132054276 6.05930993 0.012598439 0.046985818 1.76E-05 4.753288765 -0.207423712 EHYVDLK ddPTM_HeLa_Curcumin_4h_R1 2 EHYVDLK 7 0 Q32Q12;P22392-2;J3KPD9;E7ERL0;E5RHP0;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 0 ; ; 106.36 0.013596 70403200 21383.5 19473.2 21755.7 19178.6 22480.8 22827 21459.4 18990.2 17981.1 16724.7 FALSE FALSE TRUE 19690.97341 21156.37664 22561.98538 19099.24403 22212.73114 18092.42289 22061.49301 24780.22456 16008.61832 17305.88208 1.137819692 1.22249629 1.303717735 1.103627307 1.28353649 1.045449334 1.274797373 1.431896071 0.925039142 1 14.07897486 -11.88502462 0.043612531 6.73E-12 1.877189715 0.555231858 0.099563548 244.3320544 1.168948658 39.01521736 15.895971 1.30E-12 11.88502462 1.877189715 EIAEAYLGK ddPTM_HeLa_Curcumin_4h_R1 2 EIAEAYLGK 9 0 P11142;E9PKE3;P11142-2;E9PN89;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PPY6;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 ; ; 146.81 7.98E-06 16354600 9659.3 8099.1 10512.7 8043.6 10573.8 12041.7 9137.5 8927.8 8515.4 7959.2 FALSE FALSE TRUE 8894.756213 8799.150115 10902.30991 8010.317714 10447.71434 9544.115682 9393.873658 11649.84512 7581.281924 8235.781608 1.080013608 1.068404984 1.323773557 0.972623862 1.268575934 1.158859734 1.140617139 1.414540316 0.920529743 1 13.00768986 -1 0.14798191 0.963410246 2.184792566 0.482585113 0.109153166 45.43085228 0.436660785 0.220316872 11.92599733 0.1 1 1.22138232 EIAENALGK ddPTM_HeLa_Curcumin_4h_R1 2 EIAENALGK 9 0 P31942;P31942-3;P31942-2 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 0 ; ; 149.72 4.09E-06 9997000 7437.1 6440.6 6577.3 6879.4 7089.8 9783.3 7729 7603.2 8241.7 6983.6 FALSE FALSE TRUE 6848.445687 6997.296765 6821.060524 6850.934866 7005.258765 7754.133299 7945.854938 9921.380679 7337.60613 7226.27958 0.947713912 0.968312489 0.943924249 0.948058374 0.969414301 1.073046401 1.09957757 1.372958321 1.015405791 1 12.81903736 -3.649692185 0.952822292 0.969234786 2.23862913 0.945849479 0.028844836 0.844430081 0.257574813 0.004500983 1.46409819 0.000224031 3.649692185 1.269394345 EIAENITK ddPTM_HeLa_Curcumin_4h_R1 1 EIAENITK 8 0 P54136-2;P54136 P54136-2 RARS "Arginine--tRNA ligase, cytoplasmic" 0 0 131.06 0.0015598 2884000 1043.7 972.97 1214.5 1134.5 1255.5 1306.4 1235.5 993.33 1243.1 1087.7 FALSE FALSE TRUE 961.0900437 1057.069191 1259.510438 1129.80574 1240.528982 1035.437914 1270.164805 1296.191744 1106.73504 1125.497494 0.853924641 0.939201728 1.119069962 1.003827859 1.102205015 0.919982425 1.128536324 1.151661155 0.983329635 1 10.13634713 -6.813411314 9.002770661 0.929548602 1.064952112 0.408667318 0.073680382 0.241631632 39.15379726 0.013098911 0.017253743 1.54E-07 6.813411314 0.13540351 EIDCLS(ph)PEAQK ddPTM_HeLa_Curcumin_4h_R1 3 EIDCLSPEAQK 11 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 0 EIDCLS(1)PEAQK;EIDCLS(1)PEAQK;EIDCLS(1)PEAQK ;; 239.03 8.96E-24 483822000 15681.8 12157.5 12594.2 13193.2 13482.1 20256 13529.8 6623.6 14289.2 12030.6 TRUE FALSE FALSE 14440.56898 13208.34013 13060.95213 13138.61003 13321.33476 16054.67727 13909.40977 8643.105149 12721.71051 12448.66245 1.160009683 1.061024843 1.049185178 1.055423431 1.070101693 1.289670864 1.117341708 0.694299904 1.021933927 1 13.60370312 -4.258905355 24.75159668 1.08889706 0.694299743 0.694775647 0.078987735 97.73751397 954603.4964 0.012158862 0.110320043 5.51E-05 4.258905355 -0.394597318 EIDDTYIEDAADVDAR ddPTM_HeLa_Curcumin_4h_R1 2 EIDDTYIEDAADVDAR 16 0 Q99459 Q99459 CDC5L Cell division cycle 5-like protein 0 0 ; ; 383.65 1.66E-220 35743000 2787.14 2692.72 2744.6 2431.65 2874.08 3125.4 2851.8 2400.9 2365.86 2434.2 FALSE FALSE TRUE 2566.534928 2925.466718 2846.31729 2421.588477 2839.808473 2477.156809 2931.813833 3132.923358 2106.331077 2518.788269 1.018956202 1.161457973 1.13003436 0.961410098 1.127450254 0.983471632 1.163977881 1.243821641 0.836247772 1 11.29851414 -1 0.551559352 1.02474126 11.06760064 0.365691116 0.092607324 80.86209503 0.672294454 0.013181041 966.8419317 0.1 1 10.04285938 EIDLLLGQTDDTR ddPTM_HeLa_Curcumin_4h_R1 1 EIDLLLGQTDDTR 13 0 O75643;A0A494C1A5;O75643-2 O75643 SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 0 0 176.32 0.0018369 2821800 1140.2 928.74 1149 1056.1 1288.4 1311.1 1121.2 766.04 1111.8 1023.4 FALSE FALSE TRUE 1049.951967 1009.016147 1191.582951 1051.730138 1273.036671 1039.163081 1152.657854 999.6020696 989.8383216 1058.963074 0.991490632 0.952834119 1.125235601 0.993169794 1.202153978 0.981302471 1.088477854 0.943944217 0.934724115 1 10.04843657 -6.777320801 24.99885178 0.992633347 1.057634372 0.223328451 0.073693897 299.3016346 471127.9356 0.010313073 0.013578886 1.67E-07 6.777320801 0.065001025 EIEDFDSLEALR ddPTM_HeLa_Curcumin_4h_R1 1 EIEDFDSLEALR 12 0 B0QYT5;B0QYT4;P46060 B0QYT5 RANGAP1 Ran GTPase-activating protein 1 0 0 198.62 9.85E-06 6554300 1676.9 2062.1 1975 1591.6 2321.1 2194.6 1755.7 1532.1 1273.6 1474.6 FALSE FALSE TRUE 1544.171596 2240.338735 2048.195237 1585.014381 2293.422398 1739.415222 1804.960217 1999.230237 1133.889266 1525.84224 1.012012615 1.468263675 1.342337486 1.038779986 1.503053421 1.139970553 1.182927153 1.310247013 0.743123526 1 10.57539009 -7.336320157 11.09742747 1.005540515 1.275492061 0.51035195 0.157009072 0.458982165 66.95385135 0.0214133 0.024472313 4.61E-08 7.336320157 0.269951546 EIEELKELLPEIR ddPTM_HeLa_Curcumin_4h_R1 2 EIEELKELLPEIR 13 1 P49321-4;P49321;P49321-3;H0YDS9;E9PRH9;H0YF33;Q5T624;P49321-2 P49321-4 NASP Nuclear autoantigenic sperm protein 0 0 ; ; 149.41 0.00049933 55358000 6368.1 5803.4 6590.7 6479.7 6341.3 8844.8 6733.8 7405.4 8669.2 8042.1 FALSE FALSE TRUE 5864.058165 6305.020037 6834.95714 6452.888718 6265.684139 7010.288779 6922.732305 9663.27237 7718.210449 8321.562376 0.704682354 0.757672628 0.821355033 0.775441969 0.752945644 0.842424591 0.831902952 1.161232943 0.927495355 1 13.0226387 -4.261312691 22.62107563 0.832989172 1.161233149 0.596186985 0.083008111 2.062925555 366561.8749 0.01601722 0.123869755 5.48E-05 4.261312691 0.328243978 EIEIDIEPTDKVER ddPTM_HeLa_Curcumin_4h_R1 2 EIEIDIEPTDKVER 14 1 S4R3E9;Q15843;F8VSA6;E9PS38;E9PL57 S4R3E9 NEDD8-MDP1;NEDD8 NEDD8 0 0 ; ; 156.08 0.00032771 77512000 9842.2 7863.5 8564.1 8513.5 8217.7 10399.1 7715.7 7965.1 9515 8597.6 FALSE FALSE TRUE 9063.179485 8543.185901 8881.49308 8478.273393 8119.709295 8242.209438 7932.181776 10393.62232 8471.228305 8896.36596 1.018750749 0.960300637 0.998328207 0.953004118 0.91269956 0.926469243 0.891620445 1.168299772 0.952212212 1 13.11900042 -7.257845822 24.0587857 1.00885452 0.965934134 0 0.07449749 379.9712231 2543902.342 0.011341343 0.013585817 5.52E-08 7.257845822 -0.042920386 EIEMS(ph)VDDDDINSSK ddPTM_HeLa_Curcumin_4h_R1 3 EIEMSVDDDDINSSK 15 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 0 EIEMS(1)VDDDDINSSK;EIEMS(1)VDDDDINSSK;EIEMS(1)VDDDDINSSK ;; 185.86 2.05E-05 80206000 12151 9915.5 10166.9 11036.2 11066.8 15162.1 13712.7 6160.2 12542.8 10256.2 TRUE FALSE FALSE 11189.23553 10772.55164 10543.69426 10990.53513 10934.83564 12017.30955 14097.44146 8038.416622 11166.88622 10612.60219 1.054334774 1.015071652 0.993506971 1.035611713 1.030363284 1.132362199 1.32836803 0.75744068 1.052228852 1 13.37349082 -5.347161789 6.972486829 1.023781227 1.098070323 0.015134837 0.131798088 0.545453174 38.03560732 0.016851252 0.037929304 4.50E-06 5.347161789 0.074289096 AGEARPGPTAESASGPS(ph)EDPSVNFLK ddPTM_HeLa_Curcumin_4h_R1 1 AGEARPGPTAESASGPSEDPSVNFLK 26 1 Q13501;E7EMC7;Q13501-2;E9PFW8 Q13501 SQSTM1 Sequestosome-1 1 0 AGEARPGPT(0.009)AES(0.043)AS(0.275)GPS(0.595)EDPS(0.079)VNFLK 68.406 0.00029837 5021500 1556.7 1065 1119.3 1318.7 1116.7 1610.5 2026.4 3356.8 1228.7 1326.8 TRUE FALSE FALSE 1433.485552 1157.053854 1160.782243 1313.243569 1103.384082 1276.464146 2083.25533 4380.272867 1093.914684 1372.906201 1.044124902 0.842777062 0.845492752 0.95654282 0.803684972 0.929753354 1.517405434 3.190511386 0.796787634 1 10.42301735 -4.268165902 2.354861676 0.971043859 3.704977376 0.977958987 0.103198623 0.057512435 0.380598652 0.01486346 0.318510481 5.39E-05 4.268165902 2.733933517 up EIEMSVDDDDINSSK ddPTM_HeLa_Curcumin_4h_R1 2 EIEMSVDDDDINSSK 15 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 0 0 ; ; 191.06 2.14E-05 5580300 2389.87 1578.95 2146.05 2280.48 2347.58 3237.65 2473.43 2156 2311.24 2170.37 FALSE FALSE TRUE 2200.709268 1715.427402 2225.584501 2271.043978 2319.586642 2566.124894 2542.827789 2813.354475 2057.702754 2245.790196 0.979926474 0.763841344 0.991002857 1.011244943 1.032859902 1.142637856 1.132264177 1.252723643 0.916248881 1 11.13300744 -5.101031336 1.089189317 0.971051983 1.22899765 0.673194773 0.072586661 0.339944273 0.648567721 0.011562759 0.071163287 7.92E-06 5.101031336 0.257945667 EIEPNYES(ph)PSSNNQDKDSSQASK ddPTM_HeLa_Curcumin_4h_R1 1 EIEPNYESPSSNNQDKDSSQASK 23 1 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 0 EIEPNY(0.15)ES(0.367)PS(0.367)S(0.116)NNQDKDSSQASK 108.69 7.53E-06 16966000 1977.6 2071.2 1654.3 2170.4 2137.2 1891.3 1267.2 447.06 2217.5 1399.3 TRUE FALSE FALSE 1821.070873 2250.225299 1715.609813 2161.41946 2111.715286 1499.023061 1302.754222 583.366536 1974.245798 1447.925571 1.257710279 1.554102879 1.184874311 1.492769728 1.458441876 1.035290136 0.89973839 0.402898151 1.363499504 1 10.49977173 -4.365030691 1.714342268 1.20856893 0.233815388 0.678188679 0.187164831 0.424262238 1.421825915 0.031352749 0.629755669 4.31E-05 4.365030691 -0.974753542 EIEQEAAVELSQLRDPQHDLDR ddPTM_HeLa_Curcumin_4h_R1 2 EIEQEAAVELSQLRDPQHDLDR 22 1 P47985 P47985 UQCRFS1 "Cytochrome b-c1 complex subunit Rieske, mitochondrial;Cytochrome b-c1 complex subunit 11" 0 0 ; ; 83.948 0.0003046 6009700 2887.66 2999.93 3063.75 3271.9 3524.8 4765.3 3155.6 2742.03 4016.5 3254.2 FALSE FALSE TRUE 2659.098664 3259.230582 3177.29527 3258.361745 3482.769062 3776.923064 3244.137643 3578.062324 3575.899999 3367.283208 0.78968667 0.967911037 0.943578272 0.967653014 1.034296448 1.121652926 0.963428807 1.062596195 1.061954038 1 11.71736935 -6.136658583 1.469408984 0.903750365 1.045672506 0.123644274 0.080420654 0.344061182 1.460617238 0.014181112 0.028137092 7.30E-07 6.136658583 0.14192214 EIES(ph)SPQYR ddPTM_HeLa_Curcumin_4h_R1 3 EIESSPQYR 9 0 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3;H3BUF6;H3BSK9;Q8WWM7-7 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 0 EIES(0.5)S(0.5)PQYR;EIES(0.862)S(0.138)PQYR;EIES(0.499)S(0.499)PQY(0.002)R ;; 147.28 0.0018858 606241000 17303.4 14884.9 14141.8 15450.4 15317.1 23391.9 18480.9 6598.6 17049.5 12110.6 TRUE FALSE FALSE 15933.81763 16171.48443 14665.90755 15386.47034 15134.45359 18540.15626 18999.42432 8610.482764 15179.21251 12531.44245 1.271507067 1.290472705 1.170328764 1.227829151 1.207718397 1.479490995 1.516140252 0.687110267 1.211290126 1 13.61326487 -9.234014447 0.783788678 0.985527858 1.250079892 0.006235106 0.221986797 1.062184957 1.07466931 0.177549517 0.040025532 5.83E-10 9.234014447 0.264552033 EIESEIDS(ph)EEELINK ddPTM_HeLa_Curcumin_4h_R1 7 EIESEIDSEEELINK 15 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 1 0 EIESEIDS(1)EEELINK;EIES(0.002)EIDS(0.998)EEELINK;EIESEIDS(1)EEELINK;EIES(0.021)EIDS(0.979)EEELINK;EIES(0.045)EIDS(0.955)EEELINK;EIES(0.006)EIDS(0.994)EEELINK;EIESEIDS(1)EEELINK ;;;;;; 229.68 6.85E-54 93966800 14141.44 12073.88 12842.55 13792.53 13814.81 14590.29 12905.96 12844.96 14705.29 13849.18 TRUE FALSE FALSE 13022.1301 13117.49239 13318.5062 13735.46017 13650.07741 11564.09939 13268.0665 16761.32917 13092.15648 14330.43797 0.908704265 0.915358792 0.929385845 0.958481534 0.952523394 0.806960639 0.925866085 1.169631326 0.913590813 1 13.80679508 -2.84523037 13.28692382 0.950310561 0.948067642 0 0.087480241 0 0 0.011122103 0 0.001428136 2.84523037 -0.002242919 EIESEIDS(ph)EEELINKK ddPTM_HeLa_Curcumin_4h_R1 2 EIESEIDSEEELINKK 16 1 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 1 0 EIES(0.002)EIDS(0.998)EEELINKK;EIESEIDS(1)EEELINKK ; 89.913 0.0027312 6739300 2704.34 2822.09 2817.34 2720.12 3030.22 3123.82 2371.78 2714.32 3009.84 2775.46 TRUE FALSE FALSE 2490.288635 3066.018885 2921.753099 2708.864864 2994.086606 2475.904519 2438.325763 3541.903673 2679.668082 2871.907028 0.867120213 1.067589882 1.017356436 0.943228606 1.042543013 0.862111654 0.849026706 1.233293292 0.933062267 1 11.48779333 -7.265815775 24.98492302 0.937251214 0.990758275 0.07188959 0.107650189 966.7771151 5519342.068 0.018440088 0.021497761 5.42E-08 7.265815775 0.053507061 EIESEIDSEEELINK ddPTM_HeLa_Curcumin_4h_R1 1 EIESEIDSEEELINK 15 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 0 0 313.36 3.44E-107 6733500 1131.9 1258.5 1234.2 1088.1 1228.1 1290.7 1090 1041.4 1125.1 1124.8 FALSE FALSE TRUE 1042.308921 1367.279132 1279.940538 1083.597731 1213.45571 1022.994271 1120.582466 1358.918066 1001.679345 1163.886716 0.895541556 1.17475276 1.0997123 0.931016494 1.042589191 0.878946599 0.962793415 1.167569014 0.860633025 1 10.18473493 EIEVGGGR ddPTM_HeLa_Curcumin_4h_R1 2 EIEVGGGR 8 0 P62081;B5MCP9 P62081 RPS7 40S ribosomal protein S7 0 0 ; ; 108.09 0.0075642 7862100 3697.9 3741 3404.1 3547.4 3714.3 5007 3576.7 3296.7 3856.4 3413.4 FALSE FALSE TRUE 3405.207313 4064.35537 3530.258941 3532.721799 3670.009398 3968.491759 3677.052576 4301.848654 3433.362568 3532.015396 0.964097528 1.150718475 0.999502704 1.0002 1.039069479 1.123577141 1.041063575 1.217958636 0.97206897 1 11.78627592 -1 0.343649006 0.988055238 3.191235836 0.490232587 0.057537629 31.41820598 0.395458471 0.016999733 45.17352093 0.1 1 2.203180598 EIFDDDLEDDALDADEK ddPTM_HeLa_Curcumin_4h_R1 1 EIFDDDLEDDALDADEK 17 0 A0A087WU64;A6NMQ1;P09884 A0A087WU64 POLA1 DNA polymerase;DNA polymerase alpha catalytic subunit 0 0 142.39 0.002728 1626500 581.13 367.7 483.99 577.93 772.28 545.34 633.85 467.78 387.81 407.8 FALSE FALSE TRUE 535.1329473 399.4823496 501.9270952 575.5386788 763.0710654 432.2303368 651.6341251 610.4039686 345.2682133 421.9710196 1.268174643 0.946705653 1.189482386 1.363929398 1.80834946 1.024312848 1.544262745 1.446554242 0.818227312 1 8.72100011 -6.261176428 3.686878589 1.115753404 1.445618281 0.435096693 0.218480665 0.186775917 5.637709307 0.030479699 0.049884076 5.48E-07 6.261176428 0.329864877 EIFDSR ddPTM_HeLa_Curcumin_4h_R1 1 EIFDSR 6 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798 P06733 ENO1 Alpha-enolase;Enolase 0 0 150.07 4.56E-09 0 4336.3 3926.3 4004.1 4286.6 3919.7 4978.4 4362.2 5535.2 5337.9 4537.8 FALSE FALSE TRUE 3993.077279 4265.671877 4152.495468 4268.863185 3872.960138 3945.823722 4484.591592 7222.856999 4752.345725 4695.488212 0.850407263 0.908461843 0.884358618 0.909141498 0.824825867 0.840343654 0.955085262 1.53825474 1.012108967 1 12.19705945 -4.263606165 4.550107716 0.909156728 1.577829789 0.911330343 0.059014226 0.044176605 2.355142416 0.009338423 0.093917671 5.45E-05 4.263606165 0.668673061 EIFGLYGQTTGK ddPTM_HeLa_Curcumin_4h_R1 1 EIFGLYGQTTGK 12 0 Q9NR31;H0Y5E8;Q9NR31-2 Q9NR31 SAR1A GTP-binding protein SAR1a 0 0 144.1 2.30E-16 0 0 281.3 177.07 200.25 170.44 301.32 254.19 205.61 72.147 0 FALSE FALSE TRUE 0 305.6143186 183.63237 199.4214186 168.4076143 238.8228354 261.3218873 268.2995425 64.2326546 0 0 EIGGDVQK ddPTM_HeLa_Curcumin_4h_R1 1 EIGGDVQK 8 0 Q01518-2;Q01518;Q5T0R7;Q5T0R6;Q5T0R5;Q5T0R4;Q5T0R3;Q5T0R2;Q5T0R1;Q5T0R9 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1;Adenylyl cyclase-associated protein 0 0 114.5 0.0040038 7976800 5812.8 5146.9 5466.2 4895.5 5255.7 6528 5290.8 5675.6 6005.7 5322.4 FALSE FALSE TRUE 5352.710746 5591.775102 5668.782181 4875.243718 5193.02921 5174.019214 5439.245609 7406.064313 5346.889736 5507.353004 0.971920765 1.015328979 1.029311572 0.885224483 0.942926521 0.939474773 0.98763337 1.344759326 0.970863813 1 12.42714337 -4.261916738 6.281768215 0.978151426 1.353043528 0.886989371 0.039928357 0.030140895 6.47948654 0.005721574 0.047990644 5.47E-05 4.261916738 0.374892102 EIGQSVDEVEK ddPTM_HeLa_Curcumin_4h_R1 1 EIGQSVDEVEK 11 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 133.91 0.00056397 2220700 1409 1216 1121.9 1093.8 1049.9 1221.7 1191.8 970.07 1452.4 1451 FALSE FALSE TRUE 1297.476163 1321.105622 1163.478601 1089.274145 1037.380628 968.3056486 1225.2387 1265.839877 1293.075354 1501.422142 0.864164799 0.87990285 0.774917705 0.725494926 0.690932017 0.644925649 0.816052106 0.843093919 0.861233705 1 10.55211395 -7.624678585 0.566310193 0.983276595 0.737048731 0.483250075 0.070972152 0.310600398 0.233674365 0.02647249 0.023346452 2.37E-08 7.624678585 -0.246227864 EIHQFNR ddPTM_HeLa_Curcumin_4h_R1 4 EIHQFNR 7 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 ;;; ;;; 111.28 0.0125 13063700 10445.8 9044.3 9135.4 9518.6 9455.3 11920.9 8830.6 8743.3 9773.7 9390 FALSE FALSE TRUE 9619.003908 9826.048991 9473.96596 9479.214555 9342.551723 9448.370964 9078.36287 11409.09192 8701.549563 9716.301801 0.989986119 1.011295161 0.97505884 0.975599024 0.96153371 0.972424607 0.934343442 1.174221649 0.895561886 1 13.24619159 -4.251448104 24.98194008 0.986773764 1.174221752 0.730261689 0.03600024 371.4931105 928853.5825 0.003166367 0.057322406 5.60E-05 4.251448104 0.187447988 EIIDLVLDR ddPTM_HeLa_Curcumin_4h_R1 2 EIIDLVLDR 9 0 Q9BQE3;F5H5D3;A0A1W2PQM2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;P68363 Q9BQE3;P68363 TUBA1C;TUBA1B;TUBA1A Tubulin alpha-1C chain;Tubulin alpha-1B chain 0 0 ; ; 156.92 0.0092127 131667000 11831 9861.1 10713.3 10938.1 11357.1 12035.2 10068 10772.5 10792.1 10102.8 FALSE FALSE TRUE 10894.56387 10713.44954 11110.34432 10892.84104 11221.674 9538.963855 10350.48098 14056.98566 9608.233631 10453.87155 1.042155896 1.0248308 1.062797096 1.041991093 1.073446708 0.912481449 0.99010983 1.344667915 0.91910768 1 13.35174972 -4.258248214 24.99629141 1.019855401 1.344668035 0.778741831 0.05355967 89.57713073 701620.5364 0.00603486 0.057843029 5.52E-05 4.258248214 0.324812633 EIIDPVLDR ddPTM_HeLa_Curcumin_4h_R1 1 EIIDPVLDR 9 0 P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8 P68366-2 TUBA4A Tubulin alpha-4A chain 0 0 106.68 0.0047041 11933000 9645.9 8224.8 8456.6 9609.3 8913.6 9911.6 7388.1 7684.9 8734.1 8636.8 FALSE FALSE TRUE 8882.416837 8935.715063 8770.009035 9569.539263 8807.311142 7855.822433 7595.390202 10027.99063 7775.991082 8936.928157 0.993900441 0.999864261 0.98132254 1.070786191 0.985496469 0.879029382 0.849888247 1.122084732 0.870096631 1 13.12556331 -5.504074021 24.40837055 1.001671927 0.938951755 0.011645353 0.082237512 795.588469 1032665.774 0.009284004 0.020419728 3.13E-06 5.504074021 -0.062720172 EIIKQEES(ph)VDPDYWEK ddPTM_HeLa_Curcumin_4h_R1 2 EIIKQEESVDPDYWEK 16 1 F5GWX5;A0A2R8YER1;Q14839-2;Q14839;A0A2R8YFD8;A0A0C4DGG9;A0A2U3TZM0;A0A2R8Y521;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8Y212;A0A2R8Y8C1;A0A2R8YDJ9;A0A2R8YD40;A0A2R8Y5Z7;A0A2R8YE38;A0A2R8Y4X2;A0A2R8YDW2;A0A2R8Y5M9 F5GWX5 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 0 EIIKQEES(0.993)VDPDY(0.007)WEK;EIIKQEES(0.524)VDPDY(0.476)WEK ; 103.9 0.00091322 12899100 5123 5587.5 6264.3 5686.8 6330.2 7362 10107.1 5184.5 5376.9 5362.5 TRUE FALSE FALSE 4717.509144 6070.458603 6496.460469 5663.269528 6254.716499 5835.038213 10390.67802 6765.230183 4787.067522 5548.846476 0.850178351 1.094003705 1.170776755 1.020621052 1.127210228 1.051576799 1.87258344 1.219213797 0.862713997 1 12.43797217 -4.880176965 7.315896667 0.981644629 1.542361429 0.575303757 0.178116335 0.097549052 5.803383241 0.023928395 0.072718608 1.32E-05 4.880176965 0.5607168 EIK(ac)NSK(ac)DIQK ddPTM_HeLa_Curcumin_4h_R1 1 EIKNSKDIQK 10 2 I3L120;A0A0J9YXU4;A0A0J9YWI5;A0A0J9YVR1;J3KR97;Q9BTW9-2;Q9BTW9;Q9BTW9-4 I3L120 TBCD Tubulin-specific chaperone D 0 2 EIK(1)NSK(1)DIQK 96.342 0.00063216 0 149.54 172.31 232.49 161.17 126.61 199.03 232.04 164.61 208.4 200.07 FALSE TRUE FALSE 137.7037512 187.2037086 241.1062839 160.5031212 125.1002584 157.7489345 238.5504179 214.7988312 185.5390414 207.0224176 0.665163477 0.904267812 1.164638529 0.775293435 0.604283632 0.761989626 1.152292687 1.037563148 0.896226812 1 7.693643189 -4.758585217 24.99827494 0.840229374 1.094927975 0.289814385 0.155319893 78.1400293 684352.5128 0.025251634 0.086769271 1.74E-05 4.758585217 0.254698601 EIKDILIQYDR ddPTM_HeLa_Curcumin_4h_R1 1 EIKDILIQYDR 11 1 M0R210;P62249 M0R210 RPS16 40S ribosomal protein S16 0 0 85.813 0.018846 30507000 3153.7 2146.2 2389.4 2762.6 2413.8 4183.5 3225.3 2615.5 3018.9 2511.9 FALSE FALSE TRUE 2904.081317 2331.707965 2477.953266 2751.169093 2385.017012 3315.794942 3315.793238 3412.95391 2687.734223 2599.188338 1.11730315 0.897090807 0.953356565 1.05847239 0.91760069 1.275703993 1.275703337 1.313084496 1.034066744 1 11.34384546 -5.241641354 22.6327278 1.028844967 1.286918079 0.788317738 0.067772482 103.4242098 118231.4244 0.011041764 0.028087306 5.73E-06 5.241641354 0.258073112 EIKLPTEMEGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 4 EIKLPTEMEGKK 12 2 Q9NWX6 Q9NWX6 THG1L Probable tRNA(His) guanylyltransferase 0 1 ;;; EIKLPTEMEGK(1)K;EIK(0.001)LPTEMEGK(0.999)K;EIKLPTEMEGK(1)K;EIKLPTEMEGK(1)K 159.58 3.07E-06 87160000 13848.4 11776.1 11569.2 12496.4 11054.8 16507.2 17412.9 18171.9 15978 13211.6 FALSE TRUE FALSE 12752.28453 12793.97361 11997.96473 12444.69321 10922.97873 13083.42065 17901.45911 23712.42866 14225.25337 13670.70212 0.93281855 0.93586807 0.877640711 0.910318512 0.799006418 0.95704087 1.309476204 1.734543585 1.040564943 1 13.73879972 -4.456825701 2.21024329 0.940969614 1.789886459 0.939523223 0.06441663 0.075256379 0.554522753 0.009730296 0.105501122 3.49E-05 4.456825701 0.848916844 EILAELTGR ddPTM_HeLa_Curcumin_4h_R1 1 EILAELTGR 9 0 P08559-3;P08559;P08559-2;P08559-4;Q5JPU0;Q5JPT9;Q5JPU1 P08559-3 PDHA1 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial" 0 0 102.51 0.0070271 561910 203.84 0 217.15 328.11 178.91 372.46 206.99 166.23 210.93 162.84 FALSE FALSE TRUE 187.7058489 0 225.19777 326.7523678 176.7766151 295.2075975 212.7975823 216.9127618 187.7915067 168.4986779 1.11399004 0 1.336495769 1.939198407 1.049127609 1.751987619 1.262903573 1.287326194 1.114498399 1 7.396593461 -6.542086128 24.9999391 0.961626612 1.460567447 0.363641247 0.390533257 232.4355808 302532.3925 0.059407179 0.08402093 2.87E-07 6.542086128 0.498940835 EILK(ac)EQENRK ddPTM_HeLa_Curcumin_4h_R1 1 EILKEQENRK 10 2 Q99497;K7ELW0;K7EN27 Q99497 PARK7 Protein deglycase DJ-1 0 1 EILK(1)EQENRK 103.43 0.001702 4253100 270.39 492.17 481.94 491.42 748.12 1171.8 630.25 505.02 1041.5 401.1 FALSE TRUE FALSE 248.9883462 534.7109817 499.8011204 489.3866342 739.1991576 928.7554711 647.9331188 658.9982732 927.2500557 415.0381951 0.599916704 1.288341623 1.204229216 1.179136378 1.781038869 2.237759035 1.561140942 1.587801511 2.234131862 1 8.697100301 -6.250097321 1.096076813 0.828451243 1.806962826 0 0.510513948 0.201997414 0.479695778 0.04917613 0.101398212 5.62E-07 6.250097321 0.978511583 EILS(ph)PVDIIDR ddPTM_HeLa_Curcumin_4h_R1 1 EILSPVDIIDR 11 0 A0A286YF41;A0A286YEZ7;A0A286YES4;O14495 A0A286YF41 PPAP2B Lipid phosphate phosphohydrolase 3 1 0 EILS(1)PVDIIDR 115.37 0.0048017 976760 498.9 545.59 350.29 542.43 693.64 627.37 349.7 461.95 761.77 736.03 TRUE FALSE FALSE 459.4115386 592.7483685 363.2720555 540.1855684 685.368796 497.2463901 359.5116408 602.7964284 678.2057369 761.6069877 0.603213397 0.77828641 0.476980991 0.709270762 0.899898251 0.652891055 0.472043517 0.791479645 0.89049306 1 9.572902905 -9.329176916 0.894947386 1.014309879 0.666622777 0.397719914 0.131377983 0.438281422 0.586715117 0.105498783 0.023697911 4.69E-10 9.329176916 -0.347687102 EIPAS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 EIPASPSR 8 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 0 EIPAS(0.955)PS(0.045)R 97.813 0.009812 4836200 2311.6 1640.1 1778.8 1905 1966.1 2551.1 2154.1 1197.2 2345 1964.8 TRUE FALSE FALSE 2128.634421 1781.862936 1844.723893 1897.117615 1942.655542 2021.973103 2214.538249 1562.220769 2087.759367 2033.076654 1.047001556 0.876436672 0.9073558 0.933126457 0.955524986 0.994538548 1.089254674 0.768402296 1.026896533 1 10.9894489 -7.279741089 24.8836039 1.022195181 0.940527642 0.221817924 0.078282727 908.4116705 1235103.171 0.012843537 0.014703269 5.25E-08 7.279741089 -0.081667539 EIPFNEDPNPNTHS(ph)SGPSTPLK ddPTM_HeLa_Curcumin_4h_R1 1 EIPFNEDPNPNTHSSGPSTPLK 22 0 Q86YS7;H0YFE9;Q86YS7-3 Q86YS7;Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 0 EIPFNEDPNPNT(0.277)HS(0.364)S(0.277)GPS(0.041)T(0.041)PLK 52.059 0.010859 6778600 2411.3 2024.5 2114.8 2173.7 2087.4 2823.3 1499.7 1260 2322.4 2204.5 TRUE FALSE FALSE 2220.443061 2199.488759 2193.176348 2164.705805 2062.509118 2237.715755 1541.777546 1644.1682 2067.63853 2281.106211 0.973406258 0.964220232 0.961452973 0.948971948 0.904170577 0.980978327 0.675890293 0.720776697 0.906419228 1 11.15551791 -4.763466053 24.99996463 0.974634129 0.698333426 0.89301491 0.035002456 8.639509022 106579.5185 0.004443218 0.014382293 1.72E-05 4.763466053 -0.276300703 EIPS(ph)ATQSPISK ddPTM_HeLa_Curcumin_4h_R1 1 EIPSATQSPISK 12 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 0 EIPS(0.779)AT(0.003)QS(0.215)PIS(0.003)K 179.83 0.00010337 186510000 10656 8597.4 9969.4 9800.3 9058.8 10618 7401.2 3216 10256 7773.6 TRUE FALSE FALSE 9812.566356 9340.520947 10338.87473 9759.748955 8950.779726 8415.70711 7608.857753 4196.543595 9130.942459 8043.732021 1.219902196 1.161217321 1.285333065 1.213335915 1.112764536 1.046244093 0.945936256 0.521715988 1.135162439 1 12.9736493 -4.051296776 1.320232696 1.132526991 7.13E-10 0.862701662 0.076380286 0.781946562 0.821415892 0.015478095 1.350891918 8.89E-05 4.051296776 -1.13252699 EIPSATQS(ph)PISK ddPTM_HeLa_Curcumin_4h_R1 4 EIPSATQSPISK 12 0 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 0 EIPS(0.004)AT(0.001)QS(0.995)PIS(0.001)K;EIPS(0.001)AT(0.002)QS(0.994)PIS(0.002)K;EIPS(0.003)AT(0.305)QS(0.662)PIS(0.03)K;EIPS(0.01)AT(0.31)QS(0.667)PIS(0.013)K ;;; 219.84 1.85E-13 1239590000 25489 21135.2 24587.6 25683.8 22100.8 28970.3 19966.8 8984.73 26115.2 20760.3 TRUE FALSE FALSE 23471.51875 22962.03251 25498.83809 25577.52724 21837.26239 22961.53322 20527.01467 11724.13282 23250.4279 21481.71888 1.092627591 1.06891039 1.187001758 1.190664834 1.016550981 1.068887148 0.955557364 0.545772565 1.082335544 1 14.39082182 -4.231248967 2.267719219 1.066859466 0.388816706 0.873808259 0.061570317 0.203170942 1.124875423 0.010192008 0.281655643 5.87E-05 4.231248967 -0.678042761 RS(ph)PASIDR ddPTM_HeLa_Curcumin_4h_R1 2 RSPASIDR 8 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 RS(1)PASIDR;RS(1)PASIDR ; 82.494 0.01373 42002000 3357.2 2667.6 2611.5 2935 2461.5 2544.5 1163.28 683.85 3173 3148.2 TRUE FALSE FALSE 3091.474077 2898.175457 2708.284487 2922.855748 2432.14822 2016.742018 1195.918506 892.3527169 2824.929838 3257.599716 0.949003668 0.889665923 0.83137424 0.897242142 0.746607451 0.619088345 0.367116469 0.273929517 0.867181387 1 11.66959363 -4.719972714 0.608266937 0.97437847 1.06E-18 0.949994536 0.052618897 0.23787919 0.082998114 0.0079491 0.144981387 1.91E-05 4.719972714 -0.97437847 down EIPYTFEDR ddPTM_HeLa_Curcumin_4h_R1 3 EIPYTFEDR 9 0 P34897-3;P34897-2;P34897;H0YIZ0;G3V2Y4 P34897-3 SHMT2 "Serine hydroxymethyltransferase, mitochondrial;Serine hydroxymethyltransferase" 0 0 ;; ;; 176.44 0.013255 19557800 4115.29 3702.91 3406.51 4246.9 4210.11 6059.8 4064.8 3290.82 4385.6 3567.79 FALSE FALSE TRUE 3789.560454 4022.973041 3532.758257 4229.327453 4159.907188 4802.929172 4178.847348 4294.175869 3904.510652 3691.770437 1.026488651 1.089713759 0.956927934 1.145609546 1.126805488 1.300982619 1.131935861 1.163175214 1.057625527 1 11.85009713 -6.083094297 3.422769014 1.01610951 1.183266139 0.629356137 0.056451276 0.104409316 2.342862333 0.007938721 0.013918538 8.26E-07 6.083094297 0.167156628 SWDSSS(ph)PVDRPEPEAAS(ph)PTTR ddPTM_HeLa_Curcumin_4h_R1 1 SWDSSSPVDRPEPEAASPTTR 21 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 2 0 S(0.037)WDS(0.118)S(0.45)S(0.552)PVDRPEPEAAS(0.513)PT(0.257)T(0.073)R 63.095 0.0058116 63304000 2900.7 2423.2 2347.3 2205.9 2393 2365.4 1310.2 717.58 2705.7 2139.8 TRUE FALSE FALSE 2671.106534 2632.65061 2434.293003 2196.77257 2364.465038 1874.789376 1346.960686 936.3668387 2408.891479 2214.157891 1.206375817 1.189007623 1.099421596 0.992148112 1.067884566 0.846727952 0.608339943 0.422899759 1.087949278 1 11.11254239 -4.713632531 1.107348745 1.104672134 0.315854179 0.933541787 0.062489163 0.211360842 0.333108517 0.013429797 0.160617696 1.93E-05 4.713632531 -0.788817955 down EIQTAVR ddPTM_HeLa_Curcumin_4h_R1 2 EIQTAVR 7 0 P33778;P58876;P62807;P57053;O60814;Q16778;P06899;Q5QNW6;Q5QNW6-2;Q93079;U3KQK0;Q99877;Q99879;Q99880 P33778;P58876;P62807;Q16778;Q5QNW6;Q93079;U3KQK0;Q99879;Q99880 HIST1H2BB;HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST2H2BF;HIST1H2BH;HIST1H2BN;HIST1H2BM;HIST1H2BL Histone H2B type 1-B;Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 2-F;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-M;Histone H2B type 1-L 0 0 ; ; 134.81 0.0060709 193773000 10979.3 8815.5 9236.6 9325.3 9537.7 10909.8 9374.1 9343.6 9463.6 9786.9 FALSE FALSE TRUE 10110.27682 9577.472539 9578.916521 9286.714379 9423.969157 8646.984501 9637.112017 12192.42063 8425.466757 10126.99405 0.998349241 0.945736958 0.945879545 0.917025757 0.930579115 0.853855 0.951626117 1.203952582 0.831981012 1 13.30591839 -7.27168522 21.23044766 0.999220487 0.95557426 0 0.101156364 226.0473866 468392.1085 0.014286525 0.016470331 5.35E-08 7.27168522 -0.043646227 EIQVQHPAAK ddPTM_HeLa_Curcumin_4h_R1 1 EIQVQHPAAK 10 0 P49368;B4DUR8;Q5SZX9;E9PRC8;Q5SZX6 P49368 CCT3 T-complex protein 1 subunit gamma 0 0 84.658 0.009124 5350900 8395.7 6562.6 7326.6 7392 7290 7902.7 6031.4 6251.2 8546.3 7276.4 FALSE FALSE TRUE 7731.171486 7129.841902 7598.130241 7361.413863 7203.071511 6263.590938 6200.624851 8157.162103 7608.792272 7529.254358 1.026817679 0.946951924 1.009147769 0.977708218 0.956677935 0.831900563 0.823537705 1.083395741 1.01056385 1 12.87829128 -5.669523532 2.711429203 1.005829947 0.90362739 0.202384851 0.069949599 0.244092218 3.628785043 0.00979381 0.021193722 2.14E-06 5.669523532 -0.102202557 EIS(ph)DDEAEEEK ddPTM_HeLa_Curcumin_4h_R1 2 EISDDEAEEEK 11 0 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 1 0 EIS(1)DDEAEEEK;EIS(1)DDEAEEEK ; 189.24 4.44E-05 58679000 4652.2 5153.8 4537.2 3982.5 5515.9 3903.5 3682 4035.9 3091.5 3625.2 TRUE FALSE FALSE 4283.973461 5599.271507 4705.352623 3966.02147 5450.126495 3093.870098 3785.30701 5266.427331 2752.370185 3751.17543 1.142034954 1.492671194 1.254367521 1.057274325 1.452911653 0.824773503 1.009098903 1.403940559 0.733735395 1 11.87312702 -8.359019928 1.244596759 1.026177746 1.196100285 0.212451259 0.21971098 0.644508755 2.027865825 0.055977737 0.038878016 4.38E-09 8.359019928 0.169922538 EIS(ph)DDEAEEEKGEK ddPTM_HeLa_Curcumin_4h_R1 2 EISDDEAEEEKGEK 14 1 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 1 0 EIS(1)DDEAEEEKGEK;EIS(1)DDEAEEEKGEK ; 157.35 0.0033859 113075000 5912.4 6274.3 6325.1 5531.3 8445.3 6598.1 5628.6 6069.2 5327.2 5505 TRUE FALSE FALSE 5444.427301 6816.622534 6559.51377 5508.412946 8344.595313 5229.579684 5786.523367 7919.671141 4742.819488 5696.29834 0.955783384 1.196675828 1.151539715 0.96701623 1.464915427 0.918066325 1.015839238 1.390318882 0.832614306 1 12.47580899 -7.266913004 24.73854133 0.979119928 1.147326612 0.260760652 0.169459881 453.4462811 2049389.055 0.025732631 0.029876009 5.41E-08 7.266913004 0.168206684 EIS(ph)PGSGPGEIR ddPTM_HeLa_Curcumin_4h_R1 2 EISPGSGPGEIR 12 0 O43491;O43491-4;E9PHY5;E9PK52;H0Y5B0;Q6R5J7;E9PMV8;E9PMG5 O43491 EPB41L2 Band 4.1-like protein 2 1 0 EIS(0.584)PGS(0.416)GPGEIR;EIS(0.948)PGS(0.052)GPGEIR ; 113.95 0.0044064 212793000 4200.9 3786.5 3892 3445.1 4019.4 4926.9 4244.3 3839.4 4094.9 3329.7 TRUE FALSE FALSE 3868.394332 4113.788188 4036.240944 3430.845089 3971.47128 3905.005402 4363.383635 5010.015386 3645.699715 3445.406827 1.122768522 1.193992 1.171484572 0.995773579 1.152685729 1.133394574 1.266434954 1.454114314 1.058133306 1 11.75045863 -1 0.550168343 1.069158799 18.44166299 0.74443848 0.064729937 48.61349585 0.40588461 0.013958853 1002.441973 0.1 1 17.37250419 GTGQSDDSDIWDDT(ph)ALIK ddPTM_HeLa_Curcumin_4h_R1 4 GTGQSDDSDIWDDTALIK 18 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 0 GTGQSDDS(0.011)DIWDDT(0.989)ALIK;GTGQSDDS(0.001)DIWDDT(0.999)ALIK;GTGQSDDS(0.001)DIWDDT(0.999)ALIK;GTGQSDDSDIWDDT(1)ALIK ;;; 213.38 5.78E-25 66345900 7699.6 5834.66 6859.77 6466.36 6417.46 6989.04 3918.36 2314.2 7556 5906.72 TRUE FALSE FALSE 7090.168535 6338.982012 7113.999111 6439.603916 6340.935981 5539.434321 4028.298636 3019.788927 6727.125704 6111.97808 1.160044824 1.037140829 1.163943819 1.053603896 1.037460524 0.906324311 0.659082638 0.494077185 1.100646242 1 12.57742365 -4.712084589 1.366586602 1.080407896 0.438797726 0.947306197 0.047833014 0.130010167 0.356710088 0.009535939 0.091481982 1.94E-05 4.712084589 -0.64161017 down EIS(ph)QDSLAAR ddPTM_HeLa_Curcumin_4h_R1 1 EISQDSLAAR 10 0 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 0 EIS(0.993)QDS(0.007)LAAR 120.87 0.0044155 12189000 1320 1071.2 1241.6 837.64 1225 2461.5 2401.4 934.77 1211.7 825.36 TRUE FALSE FALSE 1215.520607 1163.789755 1287.614788 834.1740676 1210.392675 1950.957153 2468.776821 1219.77707 1078.779542 854.0411986 1.423257577 1.362685731 1.507672921 0.976737503 1.417253263 2.284382951 2.890699916 1.428241485 1.263146957 1 9.738161856 -5.31657948 4.32128123 1.229936717 2.274977942 0.567897248 0.368072559 0.102581343 4.023708975 0.050993263 0.12115768 4.82E-06 5.31657948 1.045041225 SSS(ph)ESLIFSGNQGR ddPTM_HeLa_Curcumin_4h_R1 1 SSSESLIFSGNQGR 14 0 Q8IZW8 Q8IZW8 TNS4 Tensin-4 1 0 S(0.253)S(0.253)S(0.492)ES(0.001)LIFSGNQGR 241.76 1.18E-28 22043000 2358.1 1711.8 1635.1 2365.3 2067.5 1459.9 1136.5 333.67 1846.8 1385.3 TRUE FALSE FALSE 2171.453897 1859.760364 1695.698244 2355.513015 2042.846413 1157.100284 1168.387131 435.404447 1644.21066 1433.439072 1.514856082 1.297411519 1.182958019 1.643259948 1.42513655 0.807219718 0.815093682 0.303748137 1.147039098 1 10.48526487 -4.709246155 1.504176251 1.285565583 0.329607658 0.705458319 0.205234306 0.288237026 1.013377539 0.036722641 0.319003769 1.95E-05 4.709246155 -0.955957925 down EIS(ph)SS(ph)PTSK ddPTM_HeLa_Curcumin_4h_R1 2 EISSSPTSK 9 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 EIS(0.989)S(0.017)S(0.991)PT(0.003)SK;EIS(0.691)S(0.317)S(0.992)PTSK ; 119.34 0.015293 460080000 28146 27531 28491 26881 26298 26649 21441 15752.1 24898 24699 TRUE FALSE FALSE 25918.2144 29910.65696 29546.90152 26769.77354 25984.41353 21121.697 22042.57675 20554.84278 22166.75169 25557.28841 1.014122233 1.170337654 1.156104711 1.047441854 1.016712458 0.826445148 0.86247713 0.8042654 0.86733582 1 14.64144716 -5.288048358 5.113550412 1.035154315 0.833165004 0.58335222 0.080503766 0.092627838 6.964478625 0.010312111 0.024448217 5.15E-06 5.288048358 -0.201989311 YGTSPCS(ph)SAVTR ddPTM_HeLa_Curcumin_4h_R1 1 YGTSPCSSAVTR 12 0 A0A0J9YYK1;O14640 A0A0J9YYK1 DVL1 Segment polarity protein dishevelled homolog DVL-1 1 0 Y(0.199)GT(0.035)S(0.183)PCS(0.343)S(0.12)AVT(0.12)R 107.53 0.00568 0 1716.8 1350.7 1457.3 1370.7 1966.9 1532 906.06 401.72 2045.8 1492.3 TRUE FALSE FALSE 1580.913468 1467.448489 1511.30882 1365.028407 1943.446002 1214.245931 931.4816051 524.2025787 1821.380858 1544.157314 1.023803374 0.95032318 0.978727236 0.883995688 1.258580317 0.786348593 0.603229734 0.339474854 1.179530636 1 10.59260402 -4.708549938 2.009659335 1.008793811 0.362616233 0.799897921 0.114589879 0.09838192 0.710741769 0.013118655 0.083889717 1.96E-05 4.708549938 -0.646177579 down EISLWFKPEELVDYK ddPTM_HeLa_Curcumin_4h_R1 1 EISLWFKPEELVDYK 15 1 Q32Q12;P22392-2;P22392 Q32Q12 NME1-NME2;NME2 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B 0 0 86.699 0.0089422 58325000 620.24 551.58 600 659.03 570.83 727.56 675.78 540.14 626.82 631.31 FALSE FALSE TRUE 571.1473495 599.2561174 622.2365278 656.3031085 564.0232251 576.6558547 694.740568 704.8261995 558.0594142 653.2479755 0.874319356 0.917348602 0.952527296 1.004676835 0.863413659 0.882751844 1.063517369 1.078956577 0.854284185 1 9.351486938 -4.742042199 20.91490424 0.934604863 1.071238355 0.559106018 0.052694839 24.16791655 26055.22127 0.008006162 0.029771068 1.81E-05 4.742042199 0.136633492 EISS(ph)SPTSK ddPTM_HeLa_Curcumin_4h_R1 1 EISSSPTSK 9 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 EIS(0.001)S(0.724)S(0.27)PT(0.004)S(0.001)K 112.71 0.0082746 6258100 3511.6 3921.6 3227 3615.9 3717.7 3379.7 2506.7 2787 3550 3924 TRUE FALSE FALSE 3233.653155 4260.56563 3346.595459 3600.938364 3673.368856 2678.712123 2577.031256 3636.74347 3160.573882 4060.358708 0.796395931 1.049307693 0.824211775 0.886852277 0.904690723 0.659723023 0.634680687 0.895670489 0.778397701 1 11.98739147 -5.274136816 23.69356515 0.905590123 0.720490334 0.332576786 0.103144392 279.6472635 521825.6627 0.014939138 0.033643705 5.32E-06 5.274136816 -0.185099789 LQDSSDPDTGSEEEGSSRLS(ph)PPHS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 LQDSSDPDTGSEEEGSSRLSPPHSPR 26 1 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF0 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 2 0 LQDS(0.047)S(0.02)DPDT(0.066)GS(0.283)EEEGS(0.199)S(0.185)RLS(0.428)PPHS(0.771)PR 50.522 0.013793 19417000 1786.8 1450.8 1754.1 1908.9 1891 1855.3 1962.3 3026.9 2078 1832.9 TRUE FALSE FALSE 1645.372895 1576.200687 1819.108489 1901.001478 1868.45106 1470.489866 2017.356857 3949.787876 1850.048599 1896.593139 0.867541309 0.831069487 0.95914535 1.002324346 0.985161774 0.775332272 1.063674025 2.082569949 0.97545887 1 10.88919451 -4.26775322 3.850163895 0.929009171 2.18897631 0.956280987 0.073796387 0.035694192 1.040608242 0.010889529 0.125324953 5.40E-05 4.26775322 1.259967139 up EISSS(ph)PTSK ddPTM_HeLa_Curcumin_4h_R1 2 EISSSPTSK 9 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 EIS(0.005)S(0.224)S(0.771)PTSK;EIS(0.001)S(0.303)S(0.695)PT(0.001)SK ; 176.48 0.00089236 686750000 23995 25651 23437 19422.6 20073.3 23465 16714.9 15367.3 20179.6 19963.2 TRUE FALSE FALSE 22095.77043 27868.15814 24305.59584 19342.23443 19833.93901 18598.09449 17183.87511 20052.71903 17965.94837 20656.91971 1.06965466 1.349095534 1.176632149 0.93635618 0.960159563 0.900332419 0.83187016 0.970750688 0.86973027 1 14.33433752 -6.109695451 6.870743646 1.072174615 0.913430489 0.333217309 0.120886789 0.24678979 13.65684802 0.017849057 0.029755504 7.77E-07 6.109695451 -0.158744126 EITALAPS(ph)TMK ddPTM_HeLa_Curcumin_4h_R1 3 EITALAPSTMK 11 0 P60709;P63267-2;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 1 0 EITALAPS(0.5)T(0.5)MK;EITALAPS(0.998)T(0.002)MK;EIT(0.001)ALAPS(0.996)T(0.002)MK ;; 169.89 0.00024177 470683000 17046 12422.7 14115.1 15874.4 13943.1 21012.9 16173.7 14796.5 17971.7 13654.3 TRUE FALSE FALSE 15696.79111 13496.46283 14638.21802 15808.71594 13776.83764 16654.58768 16627.49049 19307.88474 16000.24947 14128.78591 1.110979472 0.95524576 1.036056326 1.118901231 0.975089985 1.178769909 1.176852038 1.366563614 1.132457493 1 13.78634988 -4.085788868 0.929363237 1.04469622 1.62134302 0.700065936 0.063652467 1.068866911 0.560446131 0.009511902 0.669154224 8.21E-05 4.085788868 0.5766468 EITALAPST(ph)MK ddPTM_HeLa_Curcumin_4h_R1 1 EITALAPSTMK 11 0 P60709;P63267-2;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 1 0 EITALAPS(0.056)T(0.944)MK 149.23 0.0020082 38666000 3874.9 3017.5 3441.9 3804.7 3597.5 4925 3990.6 4015 4291.1 3371.7 TRUE FALSE FALSE 3568.197576 3278.319254 3569.459842 3788.95716 3554.602162 3903.499484 4102.565496 5239.155017 3820.377066 3488.866324 1.022738404 0.939651723 1.023100202 1.086013853 1.018841604 1.118844668 1.175902174 1.501678348 1.095019617 1 11.76854261 -1 0.725794855 1.0081448 75.33581012 0.913465809 0.043813122 43.79903866 0.19573547 0.005401227 5311.191291 0.1 1 74.32766532 EITALAPSTMK ddPTM_HeLa_Curcumin_4h_R1 5 EITALAPSTMK 11 0 P60709;P63267-2;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 0 0 ;;;; ;;;; 239.93 1.32E-51 354958500 34992.5 24664.3 29381.6 28475.3 29050.3 43212.8 34610 31898 33187.5 28516.9 FALSE FALSE TRUE 32222.8067 26796.17219 30470.50794 28357.47675 28703.89415 34249.97817 35581.06345 41623.55336 29546.91428 29507.86015 1.092007571 0.90810286 1.032623436 0.96101434 0.972754175 1.160706944 1.205816459 1.410592064 1.001323516 1 14.84881168 -4.491390448 1.350597341 1.023614484 1.473940251 0.835034639 0.05765716 0.294578792 0.62877572 0.009441997 0.160509836 3.23E-05 4.491390448 0.450325767 EITALAPSTMK(ac)IK ddPTM_HeLa_Curcumin_4h_R1 5 EITALAPSTMKIK 13 1 P60709;P63267-2;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 0 1 ;;;; EITALAPSTMK(1)IK;EITALAPSTMK(1)IK;EITALAPSTMK(1)IK;EITALAPSTMK(1)IK;EITALAPSTMK(1)IK 236.22 3.24E-38 30934400 19528.2 15681.3 16367.8 16028.2 16014.2 27079.7 20873.6 21479.7 18303.9 16310.7 FALSE TRUE FALSE 17982.52236 17036.7217 16974.40507 15961.87956 15823.24112 21463.06497 21459.25704 28028.76165 16296.00796 16877.49561 1.065473384 1.009434225 1.005741933 0.945749294 0.937534898 1.271697263 1.271471641 1.660718053 0.965546568 1 14.04281322 -4.272597025 1.108941454 1.017679291 1.948676061 0.898079658 0.06906819 0.36929472 0.364421935 0.010350507 0.399060448 5.34E-05 4.272597025 0.930996769 EIVHIQAGQCGNQIGTK ddPTM_HeLa_Curcumin_4h_R1 1 EIVHIQAGQCGNQIGTK 17 0 Q9BUF5;K7ESM5;K7ESQ3;K7EQT3;K7EJ64;K7ERA8;K7EJZ4;K7EL29;K7EN98;K7EPE5 Q9BUF5 TUBB6 Tubulin beta-6 chain 0 0 100.69 0.0019281 4665500 2052.7 2285.6 2437.7 2322.9 1761.7 2907.9 2381.6 1841.9 2196.3 2611.7 FALSE FALSE TRUE 1890.226629 2483.15708 2528.043306 2313.288455 1740.692878 2304.768761 2448.421286 2403.486831 1955.371385 2702.456381 0.6994476 0.918851863 0.935461281 0.855994743 0.644115069 0.852842169 0.905998448 0.889371184 0.723553356 1 11.40005562 -5.979248548 24.99665246 0.866593605 0.820995745 0.015811385 0.108568355 925.4006791 1114707.597 0.019532133 0.035402462 1.05E-06 5.979248548 -0.04559786 EIVHLQAGQCGNQIGAK ddPTM_HeLa_Curcumin_4h_R1 3 EIVHLQAGQCGNQIGAK 17 0 P04350;M0QYM7;M0R0X0;M0QY85;M0QY37;M0QX14;M0R042;M0R2D3;M0QZL7;M0R278;M0R2T4;P68371 P04350;P68371 TUBB4A;TUBB4B Tubulin beta-4A chain;Tubulin beta-4B chain 0 0 ;; ;; 288.45 1.82E-112 98633000 11962.5 9844.1 10895.6 10781.1 11326.2 13639.9 10273.4 10286.9 11197.8 10876.9 FALSE FALSE TRUE 11015.6555 10694.98014 11299.40052 10736.49066 11191.14246 10810.83099 10561.64395 13423.32845 9969.429356 11254.87147 0.978745562 0.950253423 1.003956425 0.953941651 0.994337652 0.960546819 0.938406448 1.192668303 0.885787935 1 13.45826196 -4.254263125 24.98942413 0.981413055 1.192668402 0.758031062 0.037659759 202.9877356 706834.0501 0.003183171 0.043010751 5.57E-05 4.254263125 0.211255347 EIVLADVIDNDSWR ddPTM_HeLa_Curcumin_4h_R1 2 EIVLADVIDNDSWR 14 0 E9PBS1;P22234;P22234-2;D6RF62 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 0 0 ; ; 286.29 2.61E-64 37101000 7707.6 7545.4 6647.3 7246.6 7371.5 7562 6748.6 6490.8 8060.8 6740.8 FALSE FALSE TRUE 7097.535327 8197.590754 6893.654786 7216.615489 7283.599677 5993.555959 6937.947553 8469.81504 7176.550407 6975.042298 1.017561618 1.175274701 0.98833161 1.034633939 1.044237349 0.859285966 0.994681789 1.214303036 1.028889876 1 12.76798625 -9.095131265 0.004855501 0.000131879 2.024835729 0.001641444 0.093812314 59830.71084 79.98363935 16998.696 16355.79191 8.03E-10 9.095131265 2.024703849 EK(ac)AEGDVAALNRR ddPTM_HeLa_Curcumin_4h_R1 1 EKAEGDVAALNRR 13 2 P67936;A0A2R8Y5V9;A0A2R8YGX3;A0A2R8YH90 P67936 TPM4 Tropomyosin alpha-4 chain 0 1 EK(1)AEGDVAALNRR 84.297 0.0066878 6247900 1523.7 1813.9 1501.4 1500.4 2301.2 3082.4 2083 2540.3 3594.4 1772.6 FALSE TRUE FALSE 1403.097537 1970.685433 1557.043205 1494.191742 2273.759693 2443.075494 2141.443374 3314.825776 3200.103313 1834.197718 0.764965262 1.07441276 0.848896054 0.814629594 1.239648087 1.331958638 1.167509562 1.807234707 1.744688308 1 10.84093345 -1.000015458 0.478533165 0.889808924 24.97516994 0.223933976 0.304917547 30.84871259 0.312374982 0.031105503 743.7463704 0.099996441 1.000015458 24.08536102 EK(ac)DFLLK ddPTM_HeLa_Curcumin_4h_R1 1 EKDFLLK 7 1 P40222 P40222 TXLNA Alpha-taxilin 0 1 EK(1)DFLLK 107.47 0.010239 0 1197.5 1361.6 1047.9 864.5 2075.3 2781.1 1680.7 1712.4 2288.7 1059.2 FALSE TRUE FALSE 1102.716611 1479.290637 1086.736096 860.9229281 2050.553403 2204.268511 1727.855919 2234.502877 2037.635336 1096.007121 1.006121758 1.349708965 0.99154109 0.785508517 1.87093073 2.011180829 1.576500631 2.038766751 1.859144249 1 10.09804146 -5.752020442 24.99652478 1.017327445 1.862844396 0.515722305 0.317643598 51.5925403 136918.2681 0.023948243 0.047391717 1.77E-06 5.752020442 0.84551695 EK(ac)EELMER ddPTM_HeLa_Curcumin_4h_R1 2 EKEELMER 8 1 P26038;P35241-4 P26038 MSN Moesin 0 1 ; EK(1)EELMER;EK(1)EELMER 132.01 0.001442 11650000 2537.8 2768.9 2345.9 2359.4 4593.1 6799.8 4878.8 4093.7 6194.2 2160.5 FALSE TRUE FALSE 2336.930452 3008.231378 2432.841118 2349.637428 4538.330282 5389.44483 5015.685997 5341.850285 5514.711757 2235.577214 1.045336496 1.345617301 1.088238466 1.051020476 2.03004855 2.410762105 2.24357538 2.389472504 2.466795476 1 11.12643166 -5.681589557 3.477521741 1.053278974 2.32583906 0.445005265 0.459962817 0.029915665 0.716631136 0.017184501 0.035637598 2.08E-06 5.681589557 1.272560086 EK(ac)ELGNDAYK ddPTM_HeLa_Curcumin_4h_R1 2 EKELGNDAYK 10 1 P31948;P31948-2;P31948-3 P31948 STIP1 Stress-induced-phosphoprotein 1 0 1 ; EK(1)ELGNDAYK;EK(1)ELGNDAYK 138.71 0.00026076 6047200 2998.8 3708.9 2925.5 2976.5 4421.4 5845.6 4417.1 3834.6 5521.3 2898.3 FALSE TRUE FALSE 2761.441816 4029.480789 3033.921604 2964.184032 4368.677693 4633.156667 4541.031938 5003.751888 4915.627204 2999.015709 0.920782711 1.343601095 1.011639117 0.98838563 1.456703838 1.54489243 1.514174109 1.668464714 1.639080178 1 11.55027336 -5.697781731 3.797079096 0.997997039 1.560778565 0.305853377 0.235111057 0.069781136 2.014775125 0.01864313 0.038113154 2.01E-06 5.697781731 0.562781526 EK(ac)EMNGETR ddPTM_HeLa_Curcumin_4h_R1 2 EKEMNGETR 9 1 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 0 1 ; EK(1)EMNGETR;EK(1)EMNGETR 123.51 0.0010658 3839800 1760.37 1401.42 1251.74 1423.65 1504.29 1644.26 1180.17 1178.04 1694.96 1848.07 FALSE TRUE FALSE 1621.034857 1522.5525 1298.130586 1417.759314 1486.352324 1303.221941 1213.282394 1537.218973 1509.027129 1912.290295 0.847692874 0.796193185 0.678835525 0.741393353 0.777262913 0.681497963 0.634465592 0.80386277 0.78912032 1 10.90108583 -7.862805719 0.502660647 0.997782308 0.701952574 0.330835587 0.080260489 0.237587129 0.146193883 0.02723146 0.018884253 1.37E-08 7.862805719 -0.295829734 EK(ac)EPIAASTNR ddPTM_HeLa_Curcumin_4h_R1 2 EKEPIAASTNR 11 1 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 1 ; EK(1)EPIAASTNR;EK(1)EPIAASTNR 134.3 0.00052261 4624500 1308.58 1518.99 1407.92 1044.58 2550.1 3222.8 2811.9 2354.2 3573.4 1112.19 FALSE TRUE FALSE 1205.004512 1650.284727 1460.098754 1040.257805 2519.691723 2554.354952 2890.794346 3071.984743 3181.40696 1150.83852 1.047066545 1.433984611 1.268726002 0.903912918 2.189439856 2.219559832 2.511902666 2.669344734 2.764425161 1 10.1684697 -5.679465734 4.310984763 1.069623579 2.432200244 0.351952633 0.56617541 0.043157362 1.497041241 0.029160154 0.05940926 2.09E-06 5.679465734 1.362576664 EK(ac)FENLGIQPPK ddPTM_HeLa_Curcumin_4h_R1 2 EKFENLGIQPPK 12 1 E9PM69;P17980;E9PMD8;E9PKD5;E9PN50;R4GNH3 E9PM69;E9PN50 PSMC3 26S protease regulatory subunit 6A 0 1 ; EK(1)FENLGIQPPK;EK(1)FENLGIQPPK 125.36 0.00069894 2225020 1158.48 1057.85 850.67 1017.14 1495.91 2079.37 1397.14 1028.558 1670.05 1384.33 FALSE TRUE FALSE 1066.785086 1149.28584 882.1965785 1012.931344 1478.07225 1648.085223 1436.339988 1342.160599 1486.849693 1432.435364 0.744735233 0.802329982 0.615871823 0.707139302 1.031859648 1.150547706 1.002725864 0.936978123 1.037987284 1 10.48425433 -5.708048943 13.54017822 0.837495515 1.037208317 0.388613597 0.129098669 1.311118629 330.9104213 0.021234083 0.042464316 1.96E-06 5.708048943 0.199712802 EK(ac)GDYILIVK ddPTM_HeLa_Curcumin_4h_R1 1 EKGDYILIVK 10 1 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 0 1 EK(1)GDYILIVK 104.79 0.0068063 910860 418.66 658.66 486.38 410.84 872.55 1188.6 928.69 728.39 1199.4 390.45 FALSE TRUE FALSE 385.5226192 715.5916355 504.4056707 409.1400529 862.1454111 942.0709617 954.746542 950.4727579 1067.828821 404.0181084 0.954221138 1.771187035 1.248472928 1.012677512 2.133927646 2.3317543 2.363128093 2.352549893 2.643022178 1 8.658276147 -5.707699566 4.350404782 1.066813897 2.331457733 0.239090246 0.551970241 0.06030528 2.350237768 0.038903382 0.078546025 1.96E-06 5.707699566 1.264643836 EK(ac)ITAFVVER ddPTM_HeLa_Curcumin_4h_R1 2 EKITAFVVER 10 1 P49748-2;P49748;P49748-3 P49748-2 ACADVL "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial" 0 1 ; EK(1)ITAFVVER;EK(1)ITAFVVER 94.465 0.013457 2070900 1928.8 1806 1497.63 2102.1 1780.14 2797.1 1872.26 1594.06 2041.87 1598.32 FALSE TRUE FALSE 1776.133445 1962.102593 1553.133485 2093.402067 1758.912993 2216.94993 1924.790577 2080.081556 1817.88197 1653.861501 1.073931187 1.186376605 0.939095253 1.265766248 1.063518917 1.340468914 1.16381606 1.25771206 1.099174247 1 10.69162271 -5.191761619 0.236081069 0.986824382 1.394783315 0.318732629 0.09918853 4.490734812 0.312220066 0.083852125 0.538124898 6.43E-06 5.191761619 0.407958933 EK(ac)K(ac)EAQLNNIDR ddPTM_HeLa_Curcumin_4h_R1 1 EKKEAQLNNIDR 12 2 Q8IYE0-2;Q8IYE0 Q8IYE0-2 CCDC146 Coiled-coil domain-containing protein 146 0 2 EK(1)K(1)EAQLNNIDR 43.991 0.020022 0 1697.2 1403.6 1525.1 1646.1 1770.9 2018 1463.9 1472.9 1485 1351.2 FALSE TRUE FALSE 1562.864829 1524.92093 1581.621548 1639.288874 1749.783174 1599.444052 1504.973094 1921.98043 1322.099215 1398.154099 1.117805848 1.090667281 1.131221192 1.172466522 1.251495221 1.14396836 1.076400015 1.374655648 0.945603361 1 10.44930766 -1.000000017 0.02296635 4.41E-08 2.668677717 0.601494919 0.072551456 1117.460457 1.995564816 82.62076788 161.7845308 0.099999996 1.000000017 2.668677673 EK(ac)LQEEMLQR ddPTM_HeLa_Curcumin_4h_R1 2 EKLQEEMLQR 10 1 P08670;B0YJC4 P08670 VIM Vimentin 0 1 ; EK(1)LQEEMLQR;EK(1)LQEEMLQR 179.57 1.06E-15 18527400 2373.5 3857.4 2569.6 2490.2 5140.4 6581.3 5156.5 4754.4 6216.8 2932.7 FALSE TRUE FALSE 2185.63497 4190.816468 2664.831636 2479.896212 5079.104087 5216.264193 5301.177512 6203.994673 5534.832594 3034.611107 0.720235606 1.381006106 0.87814601 0.81720396 1.673724872 1.71892345 1.746905065 2.044411773 1.823901778 1 11.56729593 -5.702903232 4.861720596 0.904812737 1.804602078 0.435489033 0.346149791 0.062384059 2.980066618 0.029658558 0.059707472 1.98E-06 5.702903232 0.899789341 EK(ac)NPDMVAGEK ddPTM_HeLa_Curcumin_4h_R1 2 EKNPDMVAGEK 11 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 0 1 ; EK(1)NPDMVAGEK;EK(1)NPDMVAGEK 174.24 2.95E-09 3952200 1822.5 1727.94 1417.18 1422.2 3458.6 4126.1 2766.1 2715.7 3379.2 1598.88 FALSE TRUE FALSE 1678.247202 1877.295434 1469.701937 1416.315313 3417.358454 3270.300349 2843.709321 3543.704428 3008.510214 1654.440961 1.014389296 1.134700771 0.888337494 0.856068815 2.06556688 1.976679994 1.718833968 2.141934655 1.818445194 1 10.69212809 -5.760201703 24.99999665 0.998320115 1.95746873 0.66949141 0.287545911 5.343052645 107920.7586 0.017173883 0.032884266 1.74E-06 5.760201703 0.959148615 EK(ac)PDQDAEGKAEEK ddPTM_HeLa_Curcumin_4h_R1 2 EKPDQDAEGKAEEK 14 2 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 0 1 ; EK(1)PDQDAEGKAEEK;EK(1)PDQDAEGKAEEK 121.13 0.0002309 5191400 1177.78 2214.9 1498.15 1537 2867.3 4355 3546.3 2702 3625.2 1453.56 FALSE TRUE FALSE 1084.55747 2406.346087 1553.672757 1530.640301 2833.10932 3451.723909 3645.799634 3525.827362 3227.52463 1504.071102 0.72108125 1.599888518 1.032978265 1.017664856 1.883627255 2.294920702 2.423954313 2.344189286 2.145859079 1 10.55465705 -5.617911197 1.937355069 0.93699685 2.385631037 0.487315628 0.445179007 0.084210467 0.635220478 0.038206584 0.093220787 2.41E-06 5.617911197 1.448634187 EK(ac)PTTALLDK ddPTM_HeLa_Curcumin_4h_R1 1 EKPTTALLDK 10 1 Q12906;Q12906-7;Q12906-5;Q12906-4;Q12906-2;Q12906-6;Q12906-3;K7EKJ9;K7ER69;K7EKY0 Q12906 ILF3 Interleukin enhancer-binding factor 3 0 1 EK(1)PTTALLDK 93.442 0.017174 3492000 1166 1242.3 1034.7 951.74 2000.8 2407.6 1906.3 1874.5 2208.2 1211.3 FALSE TRUE FALSE 1073.70987 1349.678876 1073.046892 947.8019521 1976.941767 1908.236621 1959.785647 2446.026421 1965.965985 1253.392585 0.856642909 1.076820537 0.856113962 0.756189213 1.577272589 1.522457244 1.563584843 1.951524567 1.56851573 1 10.29162265 -5.716185008 7.32181211 0.925539719 1.642337499 0.603894111 0.244907316 0.055721001 7.280895798 0.019886121 0.039679217 1.92E-06 5.716185008 0.71679778 EK(ac)PVCGTTYK ddPTM_HeLa_Curcumin_4h_R1 2 EKPVCGTTYK 10 1 Q14444-2;Q14444;G3V153 Q14444-2 CAPRIN1 Caprin-1 0 1 ; EK(1)PVCGTTYK;EK(1)PVCGTTYK 171.92 1.32E-12 7190300 2148.7 2915.1 2534.2 2075.36 4302.4 6311.8 4301 4103.1 5777.7 2457.7 FALSE TRUE FALSE 1978.628128 3167.068255 2628.119681 2066.77271 4251.09669 5002.661531 4421.674484 5354.116302 5143.900765 2543.104892 0.778036381 1.245354946 1.033429525 0.812696604 1.671616732 1.967147146 1.738691353 2.105346232 2.022685254 1 11.31237525 -5.656399627 4.086255562 0.928121472 1.904504717 0.41064244 0.378543846 0.051055578 1.561933888 0.024032702 0.049431903 2.21E-06 5.656399627 0.976383245 EK(ac)QPPIDNIIR ddPTM_HeLa_Curcumin_4h_R1 2 EKQPPIDNIIR 11 1 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 0 1 ; EK(1)QPPIDNIIR;EK(1)QPPIDNIIR 117.25 0.0024189 7325800 2232.3 2571.6 2306.4 2374.7 4244 5097.8 4020.6 4002.4 5287.6 2385.4 FALSE TRUE FALSE 2055.611099 2793.877645 2391.877213 2364.874121 4193.393072 4040.458816 4133.407215 5222.713335 4707.563509 2468.292472 0.832806939 1.131907048 0.969041246 0.958101257 1.698904453 1.636944917 1.67460188 2.115921591 1.907214628 1 11.26929764 -5.74300005 4.634429332 0.941142777 1.775327223 0.411861669 0.336453124 0.046109145 2.412010056 0.021334333 0.042184013 1.81E-06 5.74300005 0.834184446 EK(ac)QPVAGSEGAQYR ddPTM_HeLa_Curcumin_4h_R1 2 EKQPVAGSEGAQYR 14 1 Q9UGI8;Q9UGI8-2;F8W7T0 Q9UGI8 TES Testin 0 1 ; EK(1)QPVAGSEGAQYR;EK(1)QPVAGSEGAQYR 215.34 6.02E-27 3112300 413.33 388.71 461.17 547.1 724.43 1312.58 813.28 771.44 1095.39 458.52 FALSE TRUE FALSE 380.6144944 422.3083603 478.2613659 544.8362452 715.7916454 1040.336112 836.098448 1006.648505 975.2284575 474.4535359 0.802216583 0.890094242 1.008025717 1.148344788 1.508665425 2.192703887 1.762234623 2.121700922 2.055477268 1 8.890122998 -5.656366572 1.751860863 0.909851762 2.01281376 0.45012081 0.384762676 0.061347015 0.378962676 0.019989506 0.049439761 2.21E-06 5.656366572 1.102961998 ALATPPK(ac)LHTCEK ddPTM_HeLa_Curcumin_4h_R1 2 ALATPPKLHTCEK 13 1 E5RGS7;H0YBP7;B3KPU0;A0A087WVI1;Q96JY6;Q96JY6-3;Q96JY6-5 E5RGS7 PDLIM2 PDZ and LIM domain protein 2 0 1 ; ALATPPK(1)LHTCEK;ALATPPK(1)LHTCEK 190.35 4.29E-13 2321000000 11604.5 9721.2 9925.5 10274.4 10321.9 13138.6 12157.2 18819.3 11231.2 10173.3 FALSE TRUE FALSE 10685.99158 10561.45721 10293.34776 10231.88726 10198.81808 10413.50626 12498.29831 24557.21794 9999.165459 10526.82142 1.015120439 1.003290242 0.977821068 0.9719826 0.96884118 0.989235577 1.187281309 2.332823648 0.949875092 1 13.36178226 -4.25143078 3.01953957 0.999417169 2.566204399 0.99656527 0.02360071 0.015248957 0.199446476 0.00329628 0.057845499 5.60E-05 4.25143078 1.56678723 up EK(ac)YIDQEELNK ddPTM_HeLa_Curcumin_4h_R1 2 EKYIDQEELNK 11 1 P08238;Q58FF8;P07900;P07900-2;Q14568 P08238;P07900 HSP90AB1;HSP90AB2P;HSP90AA1;HSP90AA2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2;Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2 0 1 ; EK(1)YIDQEELNK;EK(1)YIDQEELNK 237.53 2.95E-41 9533200 3824.5 4971.6 3254 3414.7 5528.9 6437.3 5120.5 4780.7 6771.3 3137.8 FALSE TRUE FALSE 3521.786789 5401.322951 3374.596103 3400.570876 5462.971479 5102.131417 5264.167449 6238.313422 6028.505331 3246.838316 1.084681911 1.663563881 1.039348367 1.047348388 1.68255113 1.571415303 1.621321093 1.921350192 1.856730993 1 11.66481983 -1 0.21327286 0.95450315 5.909120706 0.033893455 0.340217956 21.95071273 0.259255953 0.163750696 37.40046009 0.1 1 4.954617556 EKAEGDVAALNR ddPTM_HeLa_Curcumin_4h_R1 3 EKAEGDVAALNR 12 1 P67936;A0A2R8Y5V9;A0A2R8YGX3;A0A2R8YH90 P67936 TPM4 Tropomyosin alpha-4 chain 0 0 ;; ;; 122.18 0.0028026 21799400 10813.3 8907 9916.4 9860.9 11315.8 12326.3 11203.3 10758.7 10988.2 9667.5 FALSE FALSE TRUE 9957.415895 9676.881391 10283.91051 9820.098209 11180.86648 9769.686434 11517.63445 14038.9781 9782.821951 10003.44491 0.995398684 0.967354895 1.028036902 0.981671644 1.11770161 0.976632203 1.15136681 1.403414347 0.977945302 1 13.28820929 -4.267602532 1.747609067 1.002655674 1.541771289 0.890154861 0.042805345 0.181449086 0.544579116 0.005500342 0.161468615 5.40E-05 4.267602532 0.539115615 EKAEGDVAALNRR ddPTM_HeLa_Curcumin_4h_R1 3 EKAEGDVAALNRR 13 2 P67936;A0A2R8Y5V9;A0A2R8YGX3;A0A2R8YH90 P67936 TPM4 Tropomyosin alpha-4 chain 0 0 ;; ;; 122.34 0.00088268 23165100 18281 13837.9 14025.5 16266.1 13586.2 19569.2 14890.5 16973.8 20371.2 17170.7 FALSE FALSE TRUE 16834.03956 15033.98642 14545.29737 16198.79519 13424.19344 15510.32733 15308.28735 22149.03348 18136.53033 17767.38055 0.947468847 0.846156606 0.818651761 0.911715441 0.755552762 0.872966462 0.861595063 1.246612207 1.020776826 1 14.11694338 -7.630678985 2.276854039 0.981126259 0.891251028 0.089214916 0.125082206 0.496566449 5.365477151 0.023211266 0.024029323 2.34E-08 7.630678985 -0.089875231 EKAT(ph)GRYY(ph)AMK ddPTM_HeLa_Curcumin_4h_R1 1 EKATGRYYAMK 11 2 P31749;P31749-2;J3KTC6;P31751;P31751-2;M0R0P9;C9JHS6;J3QKW1;M0R275 P31749;P31751 AKT1;AKT2 RAC-alpha serine/threonine-protein kinase;RAC-beta serine/threonine-protein kinase 2 0 EKAT(1)GRY(0.001)Y(0.999)AMK 61.353 0.017764 14604000 3125.2 3940.2 3947.2 2889 2671.8 3178.4 3911.8 2313.9 3036.8 4664.5 TRUE FALSE FALSE 2877.837122 4280.773331 4093.486704 2877.046083 2639.94053 2519.164012 4021.55458 3019.397458 2703.670638 4826.591028 0.596246317 0.886914451 0.848111365 0.596082425 0.546957576 0.521934425 0.833208067 0.625575575 0.560161535 1 12.23678887 -6.260746618 24.70606998 0.814191492 0.626298567 0.196990894 0.146255688 62.90826792 2243489.967 0.025733979 0.041065964 5.49E-07 6.260746618 -0.187892925 EKDDLS(ph)PQPLMTDFER ddPTM_HeLa_Curcumin_4h_R1 1 EKDDLSPQPLMTDFER 16 1 Q5THJ4-2;Q5THJ4 Q5THJ4-2 VPS13D Vacuolar protein sorting-associated protein 13D 1 0 EKDDLS(0.989)PQPLMT(0.011)DFER 65.855 0.013516 6772400 2088.6 1647.2 2288.9 1821.6 2079.1 2663.4 1982.4 2414.8 1970.8 1945.3 TRUE FALSE FALSE 1923.285106 1789.576628 2373.728648 1814.062702 2054.30809 2110.980817 2038.020809 3151.061404 1754.608171 2012.89903 0.955480169 0.889054345 1.179258677 0.901218926 1.020571852 1.04872663 1.012480397 1.565434409 0.871682158 1 10.97505909 -4.25819415 4.811847833 0.988765086 1.598626862 0.80438578 0.085717556 0.049176422 3.243027016 0.009821003 0.100142168 5.52E-05 4.25819415 0.609861776 EKDLLPS(ph)PAGPVPSKDPK ddPTM_HeLa_Curcumin_4h_R1 1 EKDLLPSPAGPVPSKDPK 18 2 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 0 EKDLLPS(1)PAGPVPSKDPK 60.541 0.0080715 69870000 10971 8629.3 9557.8 10424 9008.7 11595 9490 8120.1 10597 10712 TRUE FALSE FALSE 10102.63377 9375.178241 9912.020476 10380.86825 8901.277136 9190.066297 9756.263859 10595.88111 9434.535612 11084.2412 0.91144117 0.845811461 0.894244387 0.936542977 0.803056968 0.829110999 0.880192309 0.955941044 0.851166574 1 13.43622239 -8.482174859 0.588409642 1.001220033 0.87318259 0 0.063277654 0.485244093 0.347629258 0.029228964 0.012114612 3.29E-09 8.482174859 -0.128037443 EKDQAWK(ac)TLK ddPTM_HeLa_Curcumin_4h_R1 2 EKDQAWKTLK 10 2 O75528 O75528 TADA3 Transcriptional adapter 3 0 1 ; EKDQAWK(1)TLK;EKDQAWK(1)TLK 102.4 0.0019315 9775000 11719.5 8308.1 10459.1 11261.7 10438 12475.5 10912.4 10013.7 11622.6 9712.8 FALSE TRUE FALSE 10791.88921 9026.215144 10846.72345 11215.10207 10313.53367 9887.940672 11218.57257 13066.83103 10347.62986 10050.31908 1.07378573 0.898102346 1.0792417 1.115895126 1.026189675 0.983843458 1.116240439 1.300140914 1.029582223 1 13.29495368 -4.345412862 2.814880226 1.031505857 1.324972355 0.677826028 0.057364843 0.157229401 1.868213985 0.008123077 0.095233228 4.51E-05 4.345412862 0.293466499 EKDS(ph)PHMQDPNQADEEAMTQIIR ddPTM_HeLa_Curcumin_4h_R1 1 EKDSPHMQDPNQADEEAMTQIIR 23 1 P23511-2;P23511 P23511-2 NFYA Nuclear transcription factor Y subunit alpha 1 0 EKDS(0.999)PHMQDPNQADEEAMT(0.001)QIIR 51.777 0.0062898 9155400 1848.7 1425.4 1255.9 1436.3 1721.1 1821.4 1807.4 809.56 1645.3 1249.5 TRUE FALSE FALSE 1702.373444 1548.605225 1302.444759 1430.356971 1700.577007 1443.621109 1858.11078 1056.391117 1464.814706 1292.920032 1.316688892 1.197757933 1.007366834 1.106299644 1.31529945 1.116558699 1.43714285 0.817058357 1.132950739 1 10.33641733 -9.622236879 1.45349062 1.000573096 1.19203265 0.008805082 0.171453507 0.598304937 2.281006498 0.109634263 0.02541596 2.39E-10 9.622236879 0.191459554 EKDSPFK(ac)PK ddPTM_HeLa_Curcumin_4h_R1 2 EKDSPFKPK 9 2 Q15291 Q15291 RBBP5 Retinoblastoma-binding protein 5 0 1 ; EK(0.008)DSPFK(0.992)PK;EK(0.002)DSPFK(0.998)PK 78.513 0.010595 21699000 18757.3 14435.3 14801.2 15615.9 15351.2 19201.6 15155.9 16495.2 17476.6 15646.4 FALSE TRUE FALSE 17272.63991 15683.02301 15349.74549 15551.28554 15168.14697 15218.97171 15581.13376 21524.51055 15559.4607 16190.11124 1.066863573 0.968679139 0.948093887 0.96054223 0.936877255 0.940016501 0.962385838 1.329485031 0.961047177 1 13.98282528 -4.257214215 24.84164877 1.001792296 1.329485173 0.834966652 0.046002503 152.070288 894052.4763 0.008093826 0.084124885 5.53E-05 4.257214215 0.327692877 EKEIS(ph)DDEAEEEK ddPTM_HeLa_Curcumin_4h_R1 4 EKEISDDEAEEEK 13 1 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 1 0 EKEIS(1)DDEAEEEK;EKEIS(1)DDEAEEEK;EKEIS(1)DDEAEEEK;EKEIS(1)DDEAEEEK ;;; 178.14 0.0017653 370596000 13909.4 12384.9 13349.5 11614.5 15571.7 12981.4 11541.9 13750.6 10460.1 11374.7 TRUE FALSE FALSE 12808.45631 13455.39557 13844.24421 11566.44228 15386.01765 10288.91131 11865.73465 17943.09464 9312.6532 11769.96998 1.088231859 1.143197102 1.176234454 0.982707883 1.307226584 0.874166317 1.008136357 1.524480918 0.791221491 1 13.52282302 -4.257535884 24.47135058 1.059111862 1.524481164 0.507590637 0.141808787 144.8472895 908008.4241 0.014919202 0.150153597 5.53E-05 4.257535884 0.465369302 EKELS(ph)PPPGLPSK ddPTM_HeLa_Curcumin_4h_R1 2 EKELSPPPGLPSK 13 1 A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YHT2;Q7Z4S6-3;H0YI78;H0YIM6 A0A1B0GV47 KIF21A Kinesin-like protein KIF21A 1 0 EKELS(0.987)PPPGLPS(0.013)K;EKELS(1)PPPGLPSK ; 134.14 0.013138 415493000 9527.4 7362.5 7936.6 8352.3 8522.4 9754.3 7139 6704.4 9601.2 8384.1 TRUE FALSE FALSE 8773.296237 7998.881693 8230.737378 8317.740396 8420.775946 7731.148226 7339.301126 8748.540697 8547.972381 8675.446851 1.011278887 0.922013797 0.948739301 0.95876795 0.970644635 0.891152739 0.845985371 1.00842537 0.985306293 1 13.08272235 -7.263776331 24.73530584 1.005326142 0.932787595 0.318315524 0.042346693 131.061049 1387202.972 0.006928143 0.008126693 5.45E-08 7.263776331 -0.072538548 EKEPGEQASVPLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 EKEPGEQASVPLSPK 15 1 P42858 P42858 HTT Huntingtin 1 0 EKEPGEQASVPLS(1)PK;EKEPGEQASVPLS(1)PK;EKEPGEQASVPLS(1)PK;EKEPGEQASVPLS(1)PK ;;; 116.09 0.00070717 187665000 28934.2 24927.7 28951.6 29287.1 26579.7 29190 22028.5 13675 29467.6 29991.9 TRUE FALSE FALSE 26644.02754 27082.33931 30024.57176 29165.91774 26262.75444 23135.66496 22646.56042 17844.44455 26235.078 31034.11629 0.858539914 0.87266346 0.967469848 0.93980178 0.846254303 0.745491341 0.729731119 0.574994447 0.845362496 1 14.92156744 -3.544423344 0.482601382 0.939549384 1.05E-14 0.799332248 0.05386101 2.629225195 0.250515837 0.012748874 1.636830967 0.000285481 3.544423344 -0.939549384 EKETRLRDT(ph)MR ddPTM_HeLa_Curcumin_4h_R1 1 EKETRLRDTMR 11 3 Q8IZY2-2;Q8IZY2 Q8IZY2-2 ABCA7 ATP-binding cassette sub-family A member 7 1 0 EKET(0.009)RLRDT(0.991)MR 60.167 0.017597 16480000 1637.9 988.09 1177.4 1399 1173 1634.4 996.95 1394 1886.6 1287.4 TRUE FALSE FALSE 1508.258487 1073.496097 1221.03548 1393.211309 1159.012741 1295.407017 1024.921734 1819.024183 1679.6447 1332.137054 1.132209694 0.805845084 0.916598991 1.045846825 0.870040164 0.972427734 0.769381597 1.36549327 1.260864785 1 10.3795268 -7.293509244 24.99297316 1.062432351 0.954276721 0.131699499 0.170496128 1144.569967 891993.6413 0.025303498 0.028937054 5.09E-08 7.293509244 -0.10815563 EKEVDGLLTSEPMGS(ph)PVSSK ddPTM_HeLa_Curcumin_4h_R1 6 EKEVDGLLTSEPMGSPVSSK 20 1 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3;H3BUF6 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 0 EKEVDGLLTSEPMGS(0.966)PVS(0.025)S(0.008)K;EKEVDGLLTSEPMGS(0.976)PVS(0.02)S(0.003)K;EKEVDGLLTS(0.002)EPMGS(0.97)PVS(0.021)S(0.007)K;EKEVDGLLTSEPMGS(0.952)PVS(0.043)S(0.005)K;EKEVDGLLTSEPMGS(0.976)PVS(0.019)S(0.005)K;EKEVDGLLTS(0.001)EPMGS(0.969)PVS(0.023)S(0.007)K ;;;;; 131.98 0.00021054 1359025000 39840.3 33611.3 35200.7 36180.1 37893.6 43223.3 37165.3 33057.8 37647.5 32127.5 TRUE FALSE FALSE 36686.89822 36516.511 36505.26891 36030.39633 37441.74357 34258.30035 38208.05829 43136.97104 33517.66344 33243.92823 1.103566882 1.098441518 1.098103348 1.083818858 1.126273144 1.030513004 1.149324413 1.297589465 1.008234141 1 15.02080325 EKFPEFCSSPS(ph)PPVEVK ddPTM_HeLa_Curcumin_4h_R1 2 EKFPEFCSSPSPPVEVK 17 1 Q68E01-4;Q68E01-3;Q68E01-2;Q68E01 Q68E01-4 INTS3 Integrator complex subunit 3 1 0 EKFPEFCS(0.01)S(0.249)PS(0.74)PPVEVK;EKFPEFCS(0.002)S(0.068)PS(0.93)PPVEVK ; 116.45 0.00034651 133338000 8061.6 7339.9 6950.8 7819.9 7531.4 8121 6558.4 5375.2 8093.9 7255.3 TRUE FALSE FALSE 7423.515853 7974.32825 7208.402763 7787.543326 7441.592974 6436.613057 6742.411053 7014.073736 7206.01942 7507.421135 0.988823688 1.062192743 0.960170295 1.037312705 0.991231588 0.857366723 0.898099485 0.93428537 0.95985283 1 12.8741017 -5.328545823 7.235453252 1.0003877 0.896927107 0.659325086 0.034061396 0.10137359 9.578206661 0.004200852 0.009459825 4.69E-06 5.328545823 -0.103460593 EKGPTTGEGALDLSDVHS(ph)PPKS(ph)PEGK ddPTM_HeLa_Curcumin_4h_R1 1 EKGPTTGEGALDLSDVHSPPKSPEGK 26 2 O95684;O95684-2 O95684 FGFR1OP FGFR1 oncogene partner 2 0 EKGPTTGEGALDLS(0.044)DVHS(0.958)PPKS(0.998)PEGK 85.467 2.51E-05 19415000 4812.2 4031.7 4943.8 3956.2 5415.4 5273.6 4319.4 5180.1 5769.7 4506.7 TRUE FALSE FALSE 4431.309292 4380.182183 5127.021577 3939.830293 5350.824892 4179.795914 4440.590739 6759.488644 5136.778345 4663.30749 0.95025029 0.939286589 1.099438883 0.844857497 1.147431282 0.896315742 0.952240604 1.44950524 1.101531125 1 12.18713785 -4.259550719 24.98804436 0.977842446 1.449505401 0.682593131 0.09304346 55.74401062 737466.1189 0.01008424 0.087539774 5.50E-05 4.259550719 0.471662954 EKGS(ph)PGQNDQELK ddPTM_HeLa_Curcumin_4h_R1 2 EKGSPGQNDQELK 13 1 Q3T7B4;Q9H3H1-6;Q9H3H1-3;Q9H3H1-2;Q9H3H1-5;Q9H3H1-4;Q9H3H1 Q3T7B4 TRIT1 "tRNA dimethylallyltransferase, mitochondrial" 1 0 EKGS(1)PGQNDQELK;EKGS(1)PGQNDQELK ; 97.291 0.0036857 27130800 5724.4 5237.3 5280.6 5556.7 5704.7 6629.7 4489.1 4010 5711.8 4974.4 TRUE FALSE FALSE 5271.3077 5689.988875 5476.303681 5533.707848 5636.675178 5254.625488 4615.052064 5232.63054 5085.22983 5147.26003 1.024099748 1.10544034 1.063925982 1.075078355 1.095082655 1.020858759 0.896603637 1.016585622 0.987948889 1 12.32958895 -4.935543805 10.96371606 1.033566941 0.9568892 0.347410726 0.04700055 0.499876454 82.4243621 0.00698217 0.020976053 1.16E-05 4.935543805 -0.076677741 EKGSETDS(ph)AQDQPVK ddPTM_HeLa_Curcumin_4h_R1 1 EKGSETDSAQDQPVK 15 1 P30419;B7Z8J4;K7EN42 P30419 NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1 0 EKGSETDS(1)AQDQPVK 126.14 0.00037643 14743000 3435.2 3323.4 3193 3108.4 3188.4 4048 3184.4 1793.3 4043.9 3098.3 TRUE FALSE FALSE 3163.300295 3610.659887 3311.335389 3095.538264 3150.380412 3208.39917 3273.745694 2340.068915 3600.294287 3205.965694 0.986691873 1.126231604 1.032866757 0.965555642 0.982661922 1.000759046 1.021141835 0.729910778 1.122998382 1 11.64654327 -4.259287729 24.85665777 1.004269654 0.729910675 0.69769263 0.056902458 61.94890487 715601.6916 0.006059322 0.053494764 5.50E-05 4.259287729 -0.274358978 EKGSFSDT(ph)GLGDGK ddPTM_HeLa_Curcumin_4h_R1 2 EKGSFSDTGLGDGK 14 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 EKGS(0.002)FS(0.007)DT(0.991)GLGDGK;EKGSFS(0.264)DT(0.736)GLGDGK ; 195.6 3.19E-05 23353000 4819.4 3936.2 3891.6 4321.1 3846.5 5281.6 4152.2 4137.2 4422.5 4692.6 TRUE FALSE FALSE 4437.939405 4276.427589 4035.826119 4303.220433 3800.633 4186.136624 4268.699557 5398.613235 3937.362815 4855.667501 0.913971025 0.880708489 0.831157842 0.886226339 0.782721016 0.862113525 0.87911694 1.11181691 0.810879825 1 12.24545392 -8.447909296 0.807422204 0.992022035 0.884116881 0 0.099122497 0.637572759 0.86652047 0.033594586 0.017740357 3.57E-09 8.447909296 -0.107905154 EKLLS(ph)GSESSSK ddPTM_HeLa_Curcumin_4h_R1 1 EKLLSGSESSSK 12 1 G3XAI9;Q5BKY9-2;Q5BKY9 G3XAI9 FAM133B Protein FAM133B 1 0 EKLLS(0.386)GS(0.386)ES(0.048)S(0.047)S(0.133)K 71.286 0.015502 7383000 2395.4 2753.5 2164.5 2774 2985.8 3320.5 1930.2 2345.9 3833.5 3683.9 TRUE FALSE FALSE 2205.801562 2991.500271 2244.718274 2762.521923 2950.196285 2631.79087 1984.356217 3061.154111 3412.974641 3811.915251 0.578659655 0.784776175 0.588868883 0.724707068 0.773940681 0.690411695 0.52056672 0.803048838 0.895343788 1 11.89630033 -9.40244966 1.032485776 1.007368662 0.674105935 0.543816116 0.095140251 0.26840194 0.493390855 0.067667705 0.01575041 3.96E-10 9.40244966 -0.333262727 EKLQEEGGGS(ph)DEEET(ph)GSPSEDGMQSAR ddPTM_HeLa_Curcumin_4h_R1 1 EKLQEEGGGSDEEETGSPSEDGMQSAR 27 1 Q13610-2;Q13610 Q13610-2 PWP1 Periodic tryptophan protein 1 homolog 2 0 EKLQEEGGGS(1)DEEET(0.784)GS(0.2)PS(0.016)EDGMQSAR 116.49 1.05E-08 44284000 2041.8 1790.5 1465 1633.5 1758 1931.1 2156.6 2154.3 2112.6 1615.7 TRUE FALSE FALSE 1880.189376 1945.262842 1519.294189 1626.74101 1737.036998 1530.568092 2217.108392 2811.136153 1880.853065 1671.845455 1.124619127 1.163542262 0.90875277 0.973021164 1.038993762 0.915496159 1.326144343 1.681456946 1.125016107 1 10.70722578 -4.454803811 3.001083217 1.04190406 1.682918302 0.847055869 0.086424277 0.082488866 1.279410801 0.012579361 0.098868883 3.51E-05 4.454803811 0.641014243 EKLQEEGGGS(ph)DEEETGS(ph)PSEDGMQSAR ddPTM_HeLa_Curcumin_4h_R1 2 EKLQEEGGGSDEEETGSPSEDGMQSAR 27 1 Q13610-2;Q13610 Q13610-2 PWP1 Periodic tryptophan protein 1 homolog 2 0 EKLQEEGGGS(0.979)DEEET(0.297)GS(0.66)PS(0.06)EDGMQS(0.004)AR;EKLQEEGGGS(0.855)DEEET(0.45)GS(0.665)PS(0.028)EDGMQS(0.002)AR ; 80.538 4.11E-05 80516000 2629.1 1952.23 2423 2470.3 2108.2 3304.7 2691.4 2719.7 2781.9 2461.3 TRUE FALSE FALSE 2421.003961 2120.972062 2512.798511 2460.078553 2083.061092 2619.267968 2766.91344 3548.92401 2476.73253 2546.829992 0.950595041 0.832789024 0.98663771 0.965937483 0.817903472 1.028442408 1.08641466 1.393467181 0.972476584 1 11.31448694 -4.226269721 1.690425995 0.956203322 1.571493626 0.821250212 0.063927545 0.338109081 0.86536602 0.009472353 0.345300774 5.94E-05 4.226269721 0.615290304 EKLQEEGGGS(ph)DEEETGSPSEDGMQSAR ddPTM_HeLa_Curcumin_4h_R1 5 EKLQEEGGGSDEEETGSPSEDGMQSAR 27 1 Q13610-2;Q13610 Q13610-2 PWP1 Periodic tryptophan protein 1 homolog 1 0 EKLQEEGGGS(0.599)DEEET(0.342)GS(0.055)PS(0.004)EDGMQSAR;EKLQEEGGGS(1)DEEETGSPSEDGMQSAR;EKLQEEGGGS(0.999)DEEET(0.001)GSPSEDGMQSAR;EKLQEEGGGS(1)DEEETGSPSEDGMQSAR;EKLQEEGGGS(0.851)DEEET(0.123)GS(0.021)PS(0.004)EDGMQS(0.001)AR ;;;; 135.63 1.34E-08 653461800 14335.5 12368.6 13222 15015.6 13121.6 15808 12753.7 9737.43 15289.4 13167.7 TRUE FALSE FALSE 13200.83005 13437.68667 13712.01895 14953.46943 12965.13349 12529.24261 13111.5345 12706.32758 13612.19107 13625.27659 0.968848592 0.986232212 1.006366282 1.097480064 0.951550113 0.919558772 0.962294923 0.93255557 0.999039614 1 13.7339979 -5.545486183 24.99911305 0.995022778 0.939719227 0.446375365 0.035209181 201.2274444 222514.9467 0.005406736 0.010813934 2.85E-06 5.545486183 -0.055303551 EKLQSFDS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 2 EKLQSFDSPER 11 1 E9PGM9;P78332;P78332-2 E9PGM9 RBM6 RNA-binding protein 6 1 0 EKLQS(0.015)FDS(0.985)PER;EKLQS(0.091)FDS(0.909)PER ; 89.44 0.0078908 136465000 10255 8624.4 8271.9 9592.9 8994.9 11903.8 8807 3976.6 10732.2 9886.6 TRUE FALSE FALSE 9443.305929 9369.854706 8578.463891 9553.207122 8887.641692 9434.817697 9054.100717 5189.047034 9554.904511 10230.15861 0.923084997 0.915905125 0.838546519 0.93382786 0.868768709 0.92225527 0.885040111 0.50723036 0.93399378 1 13.32054089 -4.223596612 2.733749265 0.939451029 0.39989632 0.878145829 0.044902359 0.151434063 1.383923331 0.007900753 0.190963845 5.98E-05 4.223596612 -0.539554709 EKPDS(ph)DDDLDIASLVTAK ddPTM_HeLa_Curcumin_4h_R1 5 EKPDSDDDLDIASLVTAK 18 1 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 EKPDS(0.999)DDDLDIAS(0.001)LVTAK;EKPDS(1)DDDLDIASLVTAK;EKPDS(0.972)DDDLDIAS(0.025)LVT(0.003)AK;EKPDS(1)DDDLDIASLVTAK;EKPDS(1)DDDLDIASLVTAK ;;;; 100.47 0.00062938 1703131000 39834.4 37595.6 34227.4 37967.7 34713.1 39707.2 32887.8 15561.6 39992.6 35156.8 TRUE FALSE FALSE 36681.46521 40845.19614 35495.89755 37810.59972 34299.16895 31471.47913 33810.54316 20306.2602 35605.51184 36378.49618 1.008328245 1.122784074 0.975738452 1.03936676 0.942841859 0.865112152 0.929410138 0.558194052 0.978751614 1 15.15079829 -3.827360267 0.951456238 1.010206648 2.15E-20 0.828221364 0.059456645 1.1318695 0.444357426 0.008476682 1.431861245 0.000148813 3.827360267 -1.010206648 EKPELSEPSHLNGPS(ph)SDPEAAFLSR ddPTM_HeLa_Curcumin_4h_R1 1 EKPELSEPSHLNGPSSDPEAAFLSR 25 1 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 0 EKPELSEPSHLNGPS(0.5)S(0.5)DPEAAFLSR 89.631 1.42E-05 68894000 1843.5 1555.9 1613.5 1502.8 2364.6 2948.2 1918.4 1004.4 2166.2 1754.4 TRUE FALSE FALSE 1697.58503 1690.385063 1673.297729 1496.581812 2336.403689 2336.710087 1972.225141 1310.636936 1928.57328 1815.365269 0.935120363 0.931154237 0.921741623 0.824397071 1.287015748 1.287184528 1.086406782 0.721968718 1.062361009 1 10.82604415 -5.77304034 24.99993211 0.952436287 1.108665649 0.1770295 0.156889311 275.4708903 593637.1095 0.022659184 0.041321977 1.69E-06 5.77304034 0.156229362 EKPELSEPSHLNGPSS(ph)DPEAAFLSR ddPTM_HeLa_Curcumin_4h_R1 2 EKPELSEPSHLNGPSSDPEAAFLSR 25 1 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 0 EKPELSEPS(0.001)HLNGPS(0.364)S(0.622)DPEAAFLS(0.013)R;EKPELSEPSHLNGPS(0.281)S(0.683)DPEAAFLS(0.036)R ; 80.608 5.67E-05 43898500 7549.1 5362.1 5737.4 5446.2 7773.1 10041.6 6362.8 3783.4 7826 5989.6 TRUE FALSE FALSE 6951.580769 5825.576031 5950.033091 5423.665067 7680.410859 7958.858968 6541.323043 4936.941243 6967.50738 6197.738154 1.121631892 0.939951945 0.96003299 0.875103938 1.239228033 1.284155408 1.055437142 0.796571446 1.124201637 1 12.59752609 -4.262314295 8.460509223 1.05921541 0.79499303 0.299229036 0.123527584 0.088891308 99.40695062 0.017702241 0.136966379 5.47E-05 4.262314295 -0.26422238 EKPYFPIPEEYTFIQNVPLEDR ddPTM_HeLa_Curcumin_4h_R1 2 EKPYFPIPEEYTFIQNVPLEDR 22 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PRZ7;A0A1W2PQ74 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 0 ; ; 113.73 1.14E-05 185634000 5440.4 4090.7 4390.7 4324.1 4614.1 8896.9 6276.4 5721.4 5633.2 4206.6 FALSE FALSE TRUE 5009.786599 4444.28188 4553.423204 4306.20802 4559.079871 7051.582651 6452.498892 7465.828522 5015.252054 4352.779037 1.150939792 1.021021706 1.046095647 0.989300854 1.0473952 1.62001852 1.482386043 1.715186656 1.152195416 1 12.08772107 -5.262387827 24.99297734 1.059322584 1.593515996 0.919545311 0.074216892 16.69753615 440012.7496 0.010961123 0.025898649 5.47E-06 5.262387827 0.534193412 EKQIESSDYDSSSSK(ac)GK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EKQIESSDYDSSSSKGKK 18 3 Q9UNL4-8;Q9UNL4-3;Q9UNL4-6;Q9UNL4-2;Q9UNL4 Q9UNL4-8 ING4 Inhibitor of growth protein 4 0 2 ; EKQIESSDYDSSSSK(1)GK(1)K;EKQIESSDYDSSSSK(1)GK(1)K 282.67 1.53E-112 32456000 13399.3 9925.5 10050.2 11626.6 10967.1 14450.8 11587.1 9170.6 13304.4 10193.8 FALSE TRUE FALSE 12338.73127 10783.41599 10422.66925 11578.49221 10836.3245 11453.54119 11912.20284 11966.67372 11844.94061 10548.03379 1.169765997 1.022315268 0.98811489 1.097691991 1.027331227 1.085846084 1.129329226 1.134493306 1.122952471 1 13.36468648 -9.712203645 1.617806786 1.000069825 1.092853358 0 0.065857169 0.458856488 2.170066644 0.044683871 0.00984231 1.94E-10 9.712203645 0.092783533 EKQS(ph)DDEVYAPGLDIESSLK ddPTM_HeLa_Curcumin_4h_R1 2 EKQSDDEVYAPGLDIESSLK 20 1 Q15459;Q15459-2 Q15459 SF3A1 Splicing factor 3A subunit 1 1 0 EKQS(0.949)DDEVY(0.051)APGLDIESSLK;EKQS(1)DDEVYAPGLDIESSLK ; 107.09 0.00013459 143334000 12826.1 9371.9 11448.8 11949.2 11320.4 12886.4 9078.1 7105.3 11680.4 11775.9 TRUE FALSE FALSE 11810.90065 10181.96528 11873.1026 11899.75738 11185.41162 10213.61538 9332.807054 9271.673261 10399.08934 12185.11165 0.96928949 0.835607056 0.97439424 0.976581727 0.917957254 0.838204497 0.765918879 0.76090179 0.853425856 1 13.57283185 -2.52444818 0.312724571 0.992747566 4.23E-13 0.446616935 0.063481402 7.248203666 0.216951061 0.017557269 3.431100728 0.002989178 2.52444818 -0.992747566 EKS(ph)PVREPVDNLSPEER ddPTM_HeLa_Curcumin_4h_R1 4 EKSPVREPVDNLSPEER 17 2 Q86U06-3;Q86U06-5;Q86U06-2;Q86U06 Q86U06-3 RBM23 Probable RNA-binding protein 23 1 0 EKS(0.999)PVREPVDNLS(0.001)PEER;EKS(0.998)PVREPVDNLS(0.002)PEER;EKS(1)PVREPVDNLSPEER;EKS(0.992)PVREPVDNLS(0.008)PEER ;;; 65.652 0.0071945 211220000 5346.4 4854.6 5018.69 5156.91 4995.53 7081 6173.5 3916.84 6660.7 4990.1 TRUE FALSE FALSE 4923.226799 5274.209992 5204.687066 5135.572073 4935.961567 5612.320781 6346.711795 5111.066485 5930.037874 5163.505604 0.953465954 1.021439773 1.007975485 0.9945902 0.955932257 1.086920633 1.229147847 0.98984428 1.14845191 1 12.33413516 -5.149865087 4.952567469 0.983332225 1.119746121 0.157882952 0.077774053 0.12416815 4.607605789 0.0074246 0.019614155 7.08E-06 5.149865087 0.136413896 EKT(ph)PATT(ph)PEAR ddPTM_HeLa_Curcumin_4h_R1 1 EKTPATTPEAR 11 1 H0Y7U4;A0A0C4DG98;Q8NI27-2;Q8NI27;H7C477 H0Y7U4 THOC2 THO complex subunit 2 2 0 EKT(0.988)PAT(0.071)T(0.941)PEAR 101.38 0.0091454 11409000 5473.9 5021.9 5239.6 5409 5282.5 6579.5 4945.1 3898.6 5573.2 6076.6 TRUE FALSE FALSE 5040.635039 5455.970659 5433.784185 5386.618991 5219.509638 5214.837534 5083.846197 5087.265193 4961.833903 6287.761398 0.801658129 0.867712738 0.864184221 0.85668311 0.830106187 0.82936314 0.808530393 0.809074148 0.789125666 1 12.61833076 -9.366434314 0.824419167 1.01303071 0.832272709 0 0.068885153 0.206853457 0.22163568 0.025223517 0.004948446 4.30E-10 9.366434314 -0.180758001 EKT(ph)PELPEPSVK ddPTM_HeLa_Curcumin_4h_R1 2 EKTPELPEPSVK 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 EKT(0.956)PELPEPS(0.044)VK;EKT(0.996)PELPEPS(0.004)VK ; 151.22 0.0045391 698170000 9993.1 7526.9 8527.8 8873.5 8439.9 10146.5 8036.8 8930.8 9425.3 8843.7 TRUE FALSE FALSE 9202.13559 8177.491697 8843.84777 8836.783808 8339.259705 8042.001525 8262.290978 11653.75981 8391.368171 9151.017917 1.00558601 0.893615527 0.966433226 0.965661295 0.911293124 0.878809505 0.902882177 1.273493278 0.916987405 1 13.15971652 EKTMS(ph)SDDEDCSAK ddPTM_HeLa_Curcumin_4h_R1 1 EKTMSSDDEDCSAK 14 1 H0YBW3;Q9NVR2 H0YBW3 INTS10 Integrator complex subunit 10 1 0 EKTMS(0.663)S(0.337)DDEDCSAK 120.99 0.00074615 40288000 2161.9 1881.7 1829.6 1933.2 1861.6 2386.9 1840.1 842.17 2495.6 2017.3 TRUE FALSE FALSE 1990.783334 2044.345763 1897.406585 1925.200931 1839.401636 1891.830034 1891.728254 1098.943756 2221.838924 2087.401025 0.953713882 0.979373747 0.908980384 0.922295672 0.881192264 0.906308856 0.906260096 0.526465084 1.064404442 1 11.02749208 -3.939203654 1.537917534 0.960585611 1.57E-19 0.857876045 0.051485879 0.623297475 0.713026777 0.006757621 1.148207548 0.000115026 3.939203654 -0.960585611 EKTPELPEPS(ph)VK ddPTM_HeLa_Curcumin_4h_R1 1 EKTPELPEPSVK 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 EKT(0.463)PELPEPS(0.537)VK 140.31 0.011381 566250000 6749 5300.5 6010.7 5979.4 5695.9 6760.1 6183.9 5348.4 6676.8 5993.2 TRUE FALSE FALSE 6214.809528 5758.651601 6233.46183 5954.658827 5627.980113 5357.979058 6357.403591 6979.102539 5944.371745 6201.463254 1.002152117 0.928595618 1.005159843 0.960202227 0.907524544 0.863986262 1.025145733 1.125396097 0.958543412 1 12.59839295 -7.405569764 17.38083682 1.001030842 0.969308942 0 0.068720556 6.20806312 895.6444534 0.011749506 0.013435378 3.93E-08 7.405569764 -0.0317219 EKTPELPEPSVK ddPTM_HeLa_Curcumin_4h_R1 1 EKTPELPEPSVK 12 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 0 0 98 0.0089843 9116700 3736.3 2895.6 3588.9 2916.8 3428 3594.6 3536.2 3024.9 4063.9 3219.9 FALSE FALSE TRUE 3440.567912 3145.882761 3721.907791 2904.731054 3387.123339 2849.039441 3635.416255 3947.178085 3618.100337 3331.791285 1.032648092 0.94420163 1.117089119 0.871822634 1.016607299 0.855107417 1.091129649 1.184701485 1.085932469 1 11.70208231 -4.527749708 24.99353383 0.998243232 1.161308578 0.37611834 0.07954591 76.5655419 392871.1873 0.009501209 0.035812601 2.97E-05 4.527749708 0.163065347 EKTPS(ph)PKEEDEEPESPPEK ddPTM_HeLa_Curcumin_4h_R1 1 EKTPSPKEEDEEPESPPEK 19 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 EKT(0.017)PS(0.981)PKEEDEEPES(0.003)PPEK 79.311 0.0033774 117840000 1565.6 1609.6 1794.6 2197.6 1616.8 2166 1681.7 1970.9 1870.9 2143.8 TRUE FALSE FALSE 1441.681108 1748.726652 1861.109455 2188.506913 1597.520716 1716.747184 1728.883976 2571.818337 1665.666951 2218.29689 0.649904489 0.78831948 0.83898123 0.986570789 0.720156406 0.773903255 0.779374476 1.159366155 0.750876476 1 11.11523675 -4.256598754 24.30919624 0.824468813 1.159366361 0.495594797 0.104864499 307.0020634 1541657.316 0.019142861 0.207470346 5.54E-05 4.256598754 0.334897548 EKTPSPKEEDEEPES(ph)PPEK ddPTM_HeLa_Curcumin_4h_R1 1 EKTPSPKEEDEEPESPPEK 19 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 EKT(0.002)PS(0.002)PKEEDEEPES(0.995)PPEK 81.574 0.0029678 23866000 2526.2 1994.7 2238.3 2652.4 2137.5 2627.8 2198.2 3113.7 2706.5 2433.9 TRUE FALSE FALSE 2326.248604 2167.11298 2321.253367 2641.425072 2112.011709 2082.764659 2259.875576 4063.052796 2409.603721 2518.477844 0.923672452 0.860485227 0.921689017 1.04881807 0.838606428 0.826993441 0.897318029 1.613297018 0.956769871 1 11.29833632 -4.259319904 24.98141414 0.938407111 1.613297252 0.901583576 0.068521084 45.83160585 540160.2003 0.010445093 0.091970542 5.50E-05 4.259319904 0.674890141 EKTPSPKEEDEEPES(ph)PPEKK ddPTM_HeLa_Curcumin_4h_R1 1 EKTPSPKEEDEEPESPPEKK 20 3 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 EKTPSPKEEDEEPES(1)PPEKK 56.906 0.010303 249690000 3987.6 3000.2 3343.3 3645.5 3325.3 3911.2 3652.4 3305.7 4234.6 3727.2 TRUE FALSE FALSE 3671.977252 3259.523919 3467.205639 3630.415887 3285.647969 3099.973032 3754.876514 4313.592712 3770.074974 3856.719923 0.9520985 0.845154428 0.899003741 0.941322149 0.851928072 0.803784847 0.973593258 1.11846149 0.977534032 1 11.91315867 -7.883445036 1.624413911 0.986144805 0.914641679 0.090765122 0.082569879 0.529589781 2.897320268 0.018469437 0.016963547 1.31E-08 7.883445036 -0.071503126 EKVEEK(ac)ASR ddPTM_HeLa_Curcumin_4h_R1 2 EKVEEKASR 9 2 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 0 1 ; EKVEEK(1)ASR;EK(0.008)VEEK(0.992)ASR 82.831 0.0082346 15381400 9894 9183.8 9822.2 9684.7 10874.2 12591.1 13028.6 11180.9 10807.4 9179.4 FALSE TRUE FALSE 9110.87946 9977.60675 10186.21937 9644.627278 10744.53227 9979.563929 13394.14745 14589.90494 9621.855259 9498.383467 0.959203162 1.050453141 1.072416102 1.015396705 1.131195882 1.050659195 1.410150211 1.536040842 1.012999243 1 13.21346629 -3.969155213 0.704133253 0.98980901 2.171527449 0.895484609 0.058889084 0.768179803 0.201801176 0.009399187 0.792188138 0.000107361 3.969155213 1.181718439 EKVIET(ph)PENDFK ddPTM_HeLa_Curcumin_4h_R1 4 EKVIETPENDFK 12 1 Q9H0G5;A0A024QZ33 Q9H0G5 NSRP1;CCDC55 Nuclear speckle splicing regulatory protein 1 1 0 EKVIET(1)PENDFK;EKVIET(1)PENDFK;EKVIET(1)PENDFK;EKVIET(1)PENDFK ;;; 191.19 5.03E-05 64531000 21527.2 17867.1 20296 19390.8 20994 23407.7 19305.3 8077.8 21597.9 16463.7 TRUE FALSE FALSE 19823.2994 19411.45251 21048.18761 19310.56601 20743.66026 18552.67916 19846.95476 10540.68403 19228.66441 17035.81235 1.163625133 1.139449773 1.235525913 1.133527748 1.217650197 1.089039887 1.165013699 0.618736801 1.128720134 1 14.05628312 -4.257659319 24.95639612 1.111684462 0.618736608 0.836116246 0.068287442 140.5488743 927880.1349 0.01216564 0.121489375 5.53E-05 4.257659319 -0.492947854 EKVSS(ph)IDLEIDSLSSLLDDMTK ddPTM_HeLa_Curcumin_4h_R1 3 EKVSSIDLEIDSLSSLLDDMTK 22 1 Q15942;H7C3R3;C9IZ41 Q15942 ZYX Zyxin 1 0 EKVS(0.121)S(0.879)IDLEIDSLSSLLDDMTK;EKVS(0.172)S(0.825)IDLEIDS(0.002)LS(0.001)SLLDDMTK;EKVS(0.102)S(0.898)IDLEIDSLSSLLDDMTK ;; 121.21 4.13E-06 342116300 5512.5 4613.5 4834.79 5065.6 6029.8 5346 5104 4398.2 4553 4853.6 TRUE FALSE FALSE 5076.179808 5012.270383 5013.971571 5044.639889 5957.898573 4237.179338 5247.204503 5739.190933 4053.547291 5022.262239 1.010735714 0.998010487 0.998349216 1.004455691 1.186297786 0.843679429 1.044789032 1.142750151 0.807115817 1 12.29412165 -5.929106341 24.99999843 1.003972407 1.045735197 0.083065978 0.104344822 114.1515017 40252.18323 0.011579922 0.020990392 1.18E-06 5.929106341 0.04176279 EKYIDQEELNK ddPTM_HeLa_Curcumin_4h_R1 4 EKYIDQEELNK 11 1 P08238;Q58FF8;P07900;P07900-2;Q14568 P08238;P07900 HSP90AB1;HSP90AB2P;HSP90AA1;HSP90AA2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2;Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2 0 0 ;;; ;;; 205.07 9.71E-08 51995200 27693 22317.5 23016.6 26298.8 24602.2 28431.7 22010.1 24341.4 27743 24742.4 FALSE FALSE TRUE 25501.06983 24246.52526 23869.61544 26189.98253 24308.83483 22534.64493 22627.64417 31762.98081 24699.66231 25602.19656 0.996050076 0.947048633 0.932326857 1.02295842 0.949482392 0.880184045 0.883816516 1.240634987 0.964747781 1 14.64397997 -7.416540409 9.898821479 0.998261265 0.970702039 0 0.097440143 1.768865203 154.0207918 0.015531929 0.017739479 3.83E-08 7.416540409 -0.027559226 ELAEAAKEPLPVEQDDDIEVIVDET(ph)SDHTEETSPVR ddPTM_HeLa_Curcumin_4h_R1 1 ELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVR 36 1 C9JAY7;E7EVC7;Q676U5-4;Q676U5-5;Q676U5-3;Q676U5-2;Q676U5;C9JK97;C9J1B2 C9JAY7 ATG16L1 Autophagy-related protein 16-1 1 0 ELAEAAKEPLPVEQDDDIEVIVDET(0.504)S(0.374)DHT(0.119)EET(0.003)SPVR 110.04 4.88E-15 2546100 1565.6 1050.7 1064.3 1396 1096.5 1552.7 1273.7 1535.4 1514.6 1304.9 TRUE FALSE FALSE 1441.681108 1141.517826 1103.743894 1390.223722 1083.424954 1230.652517 1309.436594 2003.536392 1348.452169 1350.245178 1.06771802 0.845415222 0.817439612 1.029608359 0.802391278 0.91142893 0.969776908 1.483831548 0.998672087 1 10.39900568 -4.260772077 24.35431299 0.979223139 1.483831758 0.734880671 0.095505612 18.11955131 661089.2242 0.01517415 0.121281457 5.49E-05 4.260772077 0.504608619 ELAEAAKEPLPVEQDDDIEVIVDETSDHTEET(ph)SPVR ddPTM_HeLa_Curcumin_4h_R1 4 ELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVR 36 1 C9JAY7;E7EVC7;Q676U5-4;Q676U5-5;Q676U5-3;Q676U5-2;Q676U5;C9JK97;C9J1B2 C9JAY7 ATG16L1 Autophagy-related protein 16-1 1 0 ELAEAAKEPLPVEQDDDIEVIVDETSDHT(0.021)EET(0.571)S(0.407)PVR;ELAEAAKEPLPVEQDDDIEVIVDETS(0.001)DHT(0.05)EET(0.769)S(0.18)PVR;ELAEAAKEPLPVEQDDDIEVIVDET(0.046)S(0.123)DHT(0.154)EET(0.338)S(0.338)PVR;ELAEAAKEPLPVEQDDDIEVIVDET(0.019)S(0.016)DHT(0.064)EET(0.451)S(0.451)PVR ;;; 152.63 1.80E-19 30562800 8609.05 7144.88 5873.23 6322.54 9843.9 16160.7 7485.7 7747.9 11358.5 7308 TRUE FALSE FALSE 7927.634608 7762.45159 6090.89707 6296.379005 9726.517922 12808.78865 7695.728595 10110.19904 10112.50097 7561.952456 1.048358166 1.026514202 0.805466195 0.832639327 1.286244257 1.693846758 1.017690688 1.336982625 1.337287034 1 12.88454306 -5.647745198 6.763940244 0.994100935 1.34361022 0.381704403 0.203237782 0.140349511 7.825868502 0.024450197 0.049118121 2.25E-06 5.647745198 0.349509284 ELAEDGYSGVEVR ddPTM_HeLa_Curcumin_4h_R1 3 ELAEDGYSGVEVR 13 0 E9PL09;P23396;P23396-2;E9PPU1;E9PQ96;E9PJH4;F2Z2S8;E9PK82;H0YCJ7;H0YEU2;H0YF32 E9PL09 RPS3 40S ribosomal protein S3 0 0 ;; ;; 150.09 0.00081569 37196200 2357.7 2007.17 2097.01 1974.46 2214.56 2655.5 2247.2 2328.13 2266.3 1920.09 FALSE FALSE TRUE 2171.085557 2180.660831 2174.727035 1966.290208 2188.152818 2104.719366 2310.250384 3037.96612 2017.69256 1986.812985 1.09274782 1.097567234 1.094580644 0.989670504 1.10133809 1.059344479 1.16279207 1.529064961 1.015542266 1 10.95624037 -4.192125529 1.965141994 1.052403273 1.731231795 0.926094256 0.040051795 0.198207548 0.691817535 0.006557295 0.257033483 6.43E-05 4.192125529 0.678828522 ELAEQELEK ddPTM_HeLa_Curcumin_4h_R1 1 ELAEQELEK 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 137.05 0.00021551 2206500 1180.4 1031.9 1039.8 1449.2 1088.2 1383 948.56 954.76 1343.9 1059.4 FALSE FALSE TRUE 1086.970094 1121.092838 1078.335903 1443.203594 1075.223926 1096.15021 975.1740407 1245.861929 1196.477532 1096.214071 0.991567362 1.022695172 0.983690988 1.316534455 0.980852147 0.999941744 0.889583583 1.136513352 1.091463395 1 10.09831384 ELAILLGMLDPAEKDEK ddPTM_HeLa_Curcumin_4h_R1 2 ELAILLGMLDPAEKDEK 17 1 P30041 P30041 PRDX6 Peroxiredoxin-6 0 0 ; ; 121.45 0.00050353 57081000 6187.1 5434.2 5360.7 5761.5 4996.1 7231.1 5510.8 5415.4 6328.5 5428.7 FALSE FALSE TRUE 5697.384506 5903.908034 5559.372258 5737.66044 4936.524771 5731.288349 5665.418216 7066.530531 5634.279383 5617.346921 1.01424829 1.051013604 0.989679351 1.02141821 0.878800053 1.020283851 1.008557651 1.257983641 1.003014317 1 12.45567319 -4.260603071 5.770381555 1.001843283 1.266030575 0.765027081 0.043113792 0.048837048 7.006107251 0.005686338 0.050404049 5.49E-05 4.260603071 0.264187292 ELAPAWEDTS(ph)PEQDNR ddPTM_HeLa_Curcumin_4h_R1 1 ELAPAWEDTSPEQDNR 16 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 ELAPAWEDT(0.002)S(0.998)PEQDNR 298.1 8.86E-81 17194000 3232.1 2645.8 2984.2 2820.6 3899.9 3386.6 2597.1 2088.1 2744.1 2426 TRUE FALSE FALSE 2976.275875 2874.491163 3094.797077 2808.929105 3853.39624 2684.180985 2669.967636 2724.752078 2443.079095 2510.303319 1.185624005 1.145077226 1.232837902 1.118960041 1.535032125 1.0692656 1.063603595 1.085427429 0.973220677 1 11.29364598 -9.120770132 0.717782994 0.989770595 1.184259399 0.255212283 0.130438701 0.994432534 0.858394786 0.11368673 0.027371772 7.57E-10 9.120770132 0.194488805 ELAPYDENWFYTR ddPTM_HeLa_Curcumin_4h_R1 1 ELAPYDENWFYTR 13 0 P39019;M0R2L9;M0QYF7;M0R140 P39019 RPS19 40S ribosomal protein S19 0 0 160.86 0.00214 57786000 1938.9 1263.3 1537.4 1492 1699 2191.3 1600.7 1695.8 1382.8 1568.4 FALSE FALSE TRUE 1785.434019 1372.494023 1594.377396 1485.826499 1678.740535 1736.799679 1645.611334 2212.841613 1231.1103 1622.901783 1.100149151 0.845703688 0.982423837 0.91553692 1.034406735 1.070181632 1.013993176 1.363509262 0.758585832 1 10.66435998 -4.260753525 24.49687223 1.020627921 1.363509397 0.489206419 0.11009396 21.66929352 773745.4762 0.011056029 0.088585279 5.49E-05 4.260753525 0.342881475 ELCELKPK ddPTM_HeLa_Curcumin_4h_R1 1 ELCELKPK 8 1 E9PIZ4;E9PSD5;E9PPQ5;Q9UHD1-2;Q9UHD1 E9PIZ4 CHORDC1 Cysteine and histidine-rich domain-containing protein 1 0 0 86.011 0.015186 2492600 2837.8 2005.1 1977.2 2246.1 2114.7 2894.4 1587.1 1745.1 2846.3 2284.9 FALSE FALSE TRUE 2613.185136 2178.411909 2050.476771 2236.806233 2089.483584 2294.068813 1631.629755 2277.172957 2534.068011 2364.300105 1.105267952 0.921377073 0.867265863 0.946075428 0.883764112 0.970295103 0.690111104 0.963148862 1.07180472 1 11.20719746 -7.119956243 4.971931918 1.049404812 0.884933605 0.490223498 0.078533317 0.143830632 5.304712315 0.013132143 0.016193731 7.59E-08 7.119956243 -0.164471207 ELCEVDEDGDSWLQVTR ddPTM_HeLa_Curcumin_4h_R1 1 ELCEVDEDGDSWLQVTR 17 0 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 0 0 107.65 0.011353 2702600 406.28 457.3 526.11 418.2 532.71 307.05 345.98 375.81 404.26 523.71 FALSE FALSE TRUE 374.1225093 496.8269743 545.6080994 416.4695992 526.3577812 243.3643688 355.6872676 490.392739 359.9136894 541.9088835 0.690378993 0.91680906 1.006826269 0.768523292 0.971303105 0.449087247 0.656359913 0.904935781 0.66415905 1 9.081906487 -5.284623741 24.98380423 0.8674878 0.668750801 0.240604625 0.153908411 807.4369553 870104.5659 0.022826244 0.051070751 5.19E-06 5.284623741 -0.198736999 ELDALDANDELTPLGR ddPTM_HeLa_Curcumin_4h_R1 2 ELDALDANDELTPLGR 16 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 0 ; ; 245.55 1.71E-29 15726900 3710.6 3090 3271.7 3278.8 3276.4 4153.2 2983.1 2812 4021.1 2978.7 FALSE FALSE TRUE 3416.902095 3357.085831 3392.95208 3265.233194 3237.33107 3291.779504 3066.797757 3669.365855 3579.99539 3082.209603 1.108588492 1.089181549 1.100818087 1.059380644 1.050328007 1.067993397 0.994999741 1.190498482 1.161502899 1 11.58974926 -9.422235405 1.138330658 0.999786171 1.080894606 0 0.068571807 0.482074705 1.112623218 0.03093808 0.007712512 3.78E-10 9.422235405 0.081108434 ELDEEGS(ph)DPPLPGR ddPTM_HeLa_Curcumin_4h_R1 4 ELDEEGSDPPLPGR 14 0 C9JQV0;Q9BRJ6;H7C0T1;H7C2R9 C9JQV0 C7orf50 Uncharacterized protein C7orf50 1 0 ELDEEGS(1)DPPLPGR;ELDEEGS(1)DPPLPGR;ELDEEGS(1)DPPLPGR;ELDEEGS(1)DPPLPGR ;;; 177.93 0.00016238 236976000 13332.9 12581.6 11531 13675.9 11572.1 13973.2 13025.4 9531.9 13999 13111 TRUE FALSE FALSE 12277.5869 13669.09744 11958.349 13619.31275 11434.11027 11075.00081 13390.85767 12438.13243 12463.34472 13566.60627 0.904985864 1.007554665 0.88145471 1.003885015 0.842812862 0.81634276 0.9870455 0.91681974 0.918678148 1 13.72777225 -5.761981312 24.99999765 0.955363292 0.892317922 0.211488486 0.05849234 18.47484448 852329.6218 0.008963698 0.016993829 1.73E-06 5.761981312 -0.063045369 ELDEGRYGVYEDENYEVGS(ph)DDEEIPFK ddPTM_HeLa_Curcumin_4h_R1 2 ELDEGRYGVYEDENYEVGSDDEEIPFK 27 1 O15541 O15541 RNF113A RING finger protein 113A 1 0 ELDEGRYGVYEDENYEVGS(1)DDEEIPFK;ELDEGRY(0.002)GVY(0.002)EDENY(0.171)EVGS(0.825)DDEEIPFK ; 97.304 1.33E-06 30964000 3084.3 1756.94 1765.05 2401.2 1376.41 3133.6 1821.35 1874.89 3897.7 2825.5 TRUE FALSE FALSE 2840.1744 1908.802065 1830.464306 2391.264471 1359.99721 2483.656037 1872.452179 2446.53533 3470.132062 2923.685915 0.971436222 0.652875213 0.626081036 0.817893762 0.465165291 0.849494819 0.640442316 0.836798275 1.186903164 1 11.51357262 -7.269209396 22.13613697 0.986511597 0.694820354 0.607281766 0.127270531 53.81504691 153314.3156 0.016786424 0.019419271 5.38E-08 7.269209396 -0.291691242 DSISAVSSEKVS(ph)PSKSPSLSPSPPSPLEK ddPTM_HeLa_Curcumin_4h_R1 2 DSISAVSSEKVSPSKSPSLSPSPPSPLEK 29 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 DSISAVS(0.01)S(0.01)EKVS(0.911)PS(0.049)KS(0.014)PS(0.004)LS(0.001)PSPPSPLEK;DS(0.001)IS(0.002)AVS(0.072)S(0.072)EKVS(0.666)PS(0.165)KS(0.015)PS(0.005)LS(0.002)PS(0.001)PPSPLEK ; 106.62 9.11E-11 95443000 5019.6 4373.6 4769.6 5321.8 5307 4787.2 3084 1576.35 5084.5 4536.2 TRUE FALSE FALSE 4622.293363 4751.634496 4946.365572 5299.779802 5243.717491 3794.280757 3170.52874 2056.971858 4526.743071 4693.832612 0.984758884 1.012314432 1.053801015 1.129094333 1.117150509 0.808354509 0.675466938 0.438228635 0.964402322 1 12.19655068 -4.707816827 1.76001411 1.015592173 0.447067998 0.89940811 0.065455134 0.10388365 0.543628185 0.010056725 0.073857181 1.96E-05 4.707816827 -0.568524175 down ELDNLQY(ph)RK ddPTM_HeLa_Curcumin_4h_R1 1 ELDNLQYRK 9 1 Q7L7X3-2;Q7L7X3-3;Q7L7X3;Q9H2K8;Q9UL54-4;Q9UL54;Q9UL54-2;Q9UL54-3 Q7L7X3-2;Q9UL54-2;Q9UL54-3 TAOK1;TAOK3;TAOK2 Serine/threonine-protein kinase TAO1;Serine/threonine-protein kinase TAO3;Serine/threonine-protein kinase TAO2 1 0 ELDNLQY(1)RK 106.36 0.0089679 0 912.25 688.51 668.13 750.74 572.85 652.72 620.33 465.79 898.93 700.67 TRUE FALSE FALSE 840.0444499 748.0217365 692.8914855 747.6336368 566.0191379 517.3385143 637.7347903 607.8072268 800.319628 725.0182303 1.158652865 1.031728176 0.955688363 1.03119288 0.780696421 0.713552422 0.879612075 0.838333715 1.103861385 1 9.501873461 -5.807774756 5.027860326 1.061628513 0.801534901 0.766351042 0.065746475 0.082252215 4.593190938 0.012127696 0.022779487 1.56E-06 5.807774756 -0.260093613 ELDPSLVSANDS(ph)PSGMQTR ddPTM_HeLa_Curcumin_4h_R1 1 ELDPSLVSANDSPSGMQTR 19 0 Q5UIP0-2;Q5UIP0;H7C2B5 Q5UIP0-2 RIF1 Telomere-associated protein RIF1 1 0 ELDPSLVS(0.012)ANDS(0.898)PS(0.089)GMQTR 87.157 0.0031607 16058000 2116.9 2029.7 2131.6 2520.6 2055.5 2579.3 2225.6 578.5 2905.6 2434.6 TRUE FALSE FALSE 1949.345131 2205.138224 2210.598971 2510.170425 2030.989505 2044.324105 2288.044346 754.8819869 2586.862949 2519.202169 0.773794638 0.875331981 0.87749963 0.99641484 0.80620346 0.811496644 0.908241655 0.299651213 1.026858019 1 11.29875119 -4.260076788 24.93082888 0.885346916 0.299651015 0.819857225 0.083877483 38.65497984 707175.7359 0.01278228 0.106983607 5.49E-05 4.260076788 -0.585695901 ELDQDMVT(ph)EDEDDPGSHKR ddPTM_HeLa_Curcumin_4h_R1 1 ELDQDMVTEDEDDPGSHKR 19 1 Q9NRL2;Q9NRL2-2;A0A087WWN7 Q9NRL2 BAZ1A Bromodomain adjacent to zinc finger domain protein 1A 1 0 ELDQDMVT(0.999)EDEDDPGS(0.001)HKR 43.326 0.015431 14712000 3683.5 3035.5 3571.6 4064.7 4788.6 4429.7 4157.7 2528.2 3740.8 3398.6 TRUE FALSE FALSE 3391.947088 3297.875094 3703.966638 4047.881348 4731.499073 3510.930287 4274.353872 3299.036542 3330.443599 3516.701097 0.964525274 0.937775206 1.053250343 1.151045038 1.345436801 0.998359027 1.215444177 0.938105472 0.947036301 1 11.780007 -6.487878515 3.845489179 0.979552879 1.137970026 0.349790995 0.105999549 0.188495927 5.939017181 0.015402921 0.023326644 3.25E-07 6.487878515 0.158417147 ELDS(ph)LNSDRLRTVQLNVCS(ph)S(ph)EEVEK ddPTM_HeLa_Curcumin_4h_R1 1 ELDSLNSDRLRTVQLNVCSSEEVEK 25 2 C9JM78;C9JQ90;A0A0G2JRX6;Q02338;C9K0G7;E9PCG9 C9JM78 BDH1 "D-beta-hydroxybutyrate dehydrogenase, mitochondrial" 3 0 ELDS(0.992)LNS(0.013)DRLRT(0.013)VQLNVCS(0.991)S(0.991)EEVEK 49.577 0.019486 11053000 1055.6 805.43 1179.5 1035.4 1043 1130 1007 1068 1157.7 1201.8 TRUE FALSE FALSE 972.0481461 875.0477803 1223.213308 1031.115789 1030.562906 895.6252623 1035.25371 1393.628284 1030.703206 1243.562461 0.781664112 0.703662106 0.983636405 0.829162846 0.82871825 0.720209311 0.832490319 1.120674134 0.828831071 1 10.28026326 -9.418648065 1.172134049 0.999148654 0.838043837 0 0.127687611 0.594053802 1.471838836 0.07632834 0.019692937 3.81E-10 9.418648065 -0.161104817 T(ph)QTPPVEENVTQK ddPTM_HeLa_Curcumin_4h_R1 1 TQTPPVEENVTQK 13 0 Q6P1Q9;Q6P1Q9-2 Q6P1Q9 METTL2B Methyltransferase-like protein 2B 1 0 T(0.975)QT(0.025)PPVEENVTQK 118.52 0.0076622 34432000 3164.8 2871.6 2640.9 3025.5 2937.2 3088 3270.9 5117.7 2643.1 2781.6 TRUE FALSE FALSE 2914.302741 3119.808308 2738.774077 3012.981283 2902.175808 2447.513991 3362.672651 6678.063171 2353.158543 2878.260393 1.012522268 1.083921495 0.951537979 1.046806359 1.008308983 0.850344881 1.168300359 2.320173389 0.817562771 1 11.4909814 -4.267715282 3.676579255 1.00228633 2.455619649 0.958495248 0.083504333 0.023256611 0.580655151 0.007502154 0.091242298 5.40E-05 4.267715282 1.453333319 up ELEDATETADAMNR ddPTM_HeLa_Curcumin_4h_R1 10 ELEDATETADAMNR 14 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ;;;;;;;;; ;;;;;;;;; 317.75 3.29E-107 275198000 18389.46 15627.99 16298.72 16249.99 16801.47 20510.42 15724.69 14369.39 18613.1 16559.12 FALSE FALSE TRUE 16933.91484 16978.80382 16902.7649 16182.75185 16601.12344 16256.32769 16165.88248 18750.55086 16571.2895 17134.54819 0.988290712 0.990910506 0.986472752 0.944451623 0.968868467 0.948745629 0.9434671 1.094312535 0.96712731 1 14.06462053 -6.51351911 22.48596828 0.993793999 0.974577088 0 0.042071406 313.4238046 752980.1197 0.00601089 0.008787574 3.07E-07 6.51351911 -0.019216911 ELEDDEQFVSLYGTEEYLHPDMYER ddPTM_HeLa_Curcumin_4h_R1 1 ELEDDEQFVSLYGTEEYLHPDMYER 25 0 A0A494C1I2;A0A494C079;A0A494C0R4;A0A494C0A8;A0A494C1M6;A0A494C0X2;A0A494C167;A0A494C148;A0A494C045;Q9UHD2 A0A494C1I2 TBK1 Serine/threonine-protein kinase TBK1 0 0 83.826 0.00041467 1268600 558.78 547.07 502.19 645.77 735.33 667.89 518.56 502.25 653.42 607.24 FALSE FALSE TRUE 514.5519734 594.3562931 520.8016032 643.0979748 726.56167 529.3620853 533.109398 655.3837129 581.7414608 628.3415448 0.818904906 0.945912773 0.828851136 1.023484728 1.156316459 0.842475067 0.848438882 1.043037371 0.925836379 1 9.295405161 -6.242091065 24.85870843 0.909329377 0.977138213 0.134831831 0.098883037 1664.335765 2138338.333 0.016828843 0.027876325 5.73E-07 6.242091065 0.067808836 ELEDPESAMLDTLDR ddPTM_HeLa_Curcumin_4h_R1 1 ELEDPESAMLDTLDR 15 0 F8VS10;Q86XZ4 F8VS10 SPATS2 Spermatogenesis-associated serine-rich protein 2 0 0 178.71 0.00057714 3013200 1224.2 1181.5 1132.7 1090.6 1239 1325.7 1083.4 1103.1 1237.3 856.05 FALSE FALSE TRUE 1127.303278 1283.623595 1174.678858 1086.087386 1224.225734 1050.734876 1113.797288 1439.430112 1101.571286 885.7976738 1.272641949 1.449116015 1.326125472 1.226112258 1.382060227 1.186201892 1.257394686 1.625010038 1.243592434 1 9.790833398 -8.790983341 0.592515431 0.981701076 1.341517318 0.210198714 0.140330752 0.533691099 0.343919572 0.09674931 0.029221456 1.62E-09 8.790983341 0.359816242 ELEEDFIK ddPTM_HeLa_Curcumin_4h_R1 1 ELEEDFIK 8 0 H3BT58;Q14019 H3BT58 COTL1 Coactosin-like protein 0 0 128.1 0.0018484 2836600 3177.3 2591 2968.2 3395.8 3264.6 2966.7 2619.4 2742 2717.7 2095.3 FALSE FALSE TRUE 2925.813352 2814.954495 3078.204103 3381.749079 3225.671777 2351.372978 2692.893314 3578.023177 2419.575109 2168.111519 1.349475489 1.29834396 1.41976281 1.559767129 1.487779456 1.084525846 1.242045573 1.650294805 1.115982775 1 11.08222325 -9.016770039 0.572736228 0.95999886 1.390478882 0.415134262 0.155148387 0.758944239 0.40570508 0.168833967 0.03842232 9.62E-10 9.016770039 0.430480022 ELEEEEENS(ph)DEDELDSHTMVK ddPTM_HeLa_Curcumin_4h_R1 1 ELEEEEENSDEDELDSHTMVK 21 0 E5RFQ9;A0A087WZ06;Q13188;Q13188-2 E5RFQ9 STK3 Serine/threonine-protein kinase 3;Serine/threonine-protein kinase 3 36kDa subunit;Serine/threonine-protein kinase 3 20kDa subunit 1 0 ELEEEEENS(1)DEDELDSHTMVK 185.96 1.08E-10 70610000 2840.9 2270.9 2380.8 2633.2 2830.7 2675.2 2035.9 1800.8 2772.3 2576.2 TRUE FALSE FALSE 2616.039767 2467.186477 2469.034542 2622.304516 2796.945751 2120.333364 2093.021875 2349.85563 2468.185626 2665.722758 0.981362281 0.925522532 0.926215802 0.983712394 1.049226047 0.795406558 0.785161123 0.881507885 0.925897346 1 11.38031103 -5.252092505 24.99789515 0.98373081 0.81713877 0.692988653 0.044987844 235.7545981 630516.0061 0.005922474 0.014878966 5.60E-06 5.252092505 -0.16659204 ELEEEEENSDEDELDSHT(ph)MVK ddPTM_HeLa_Curcumin_4h_R1 1 ELEEEEENSDEDELDSHTMVK 21 0 E5RFQ9;A0A087WZ06;Q13188;Q13188-2 E5RFQ9 STK3 Serine/threonine-protein kinase 3;Serine/threonine-protein kinase 3 36kDa subunit;Serine/threonine-protein kinase 3 20kDa subunit 1 0 ELEEEEENS(0.003)DEDELDS(0.433)HT(0.564)MVK 69.148 0.0039719 4655600 1464.4 1177.1 1240.5 1094.8 1590.7 1566.1 1161.4 1149.2 1431.7 1296.6 TRUE FALSE FALSE 1348.491195 1278.843279 1286.474021 1090.270008 1571.731941 1241.273206 1193.985758 1499.58579 1274.646092 1341.656753 1.005094031 0.953182158 0.958869709 0.812629612 1.171485879 0.925179412 0.889933849 1.117711953 0.950053796 1 10.38979991 -7.281763581 22.33380253 1.002405519 0.970964469 0 0.099343864 762.5910369 837990.9387 0.015537232 0.017785408 5.23E-08 7.281763581 -0.031441051 ELEELKEIEADLER ddPTM_HeLa_Curcumin_4h_R1 1 ELEELKEIEADLER 14 1 K7EJH0;K7EMX1;K7EJV2;K7ESQ2;Q8NBT2 K7EJH0 SPC24 Kinetochore protein Spc24 0 0 88.101 0.010096 2623900 1179 822.2 1074.8 1166.5 1255.2 1281.6 991.91 1368.1 1171.8 1083.1 FALSE FALSE TRUE 1085.680906 893.2673043 1114.633033 1161.673332 1240.23256 1015.781713 1019.740325 1785.227392 1043.256472 1120.737644 0.968719942 0.797035157 0.994553042 1.036525665 1.106621667 0.906351026 0.909883174 1.592903924 0.930865914 1 10.13023288 -4.257731522 24.99773957 0.975515909 1.59290416 0.846371513 0.080535356 101.7292656 685811.7147 0.010928388 0.109264283 5.52E-05 4.257731522 0.617388251 ELEEVS(ph)PETPVVPATTQR ddPTM_HeLa_Curcumin_4h_R1 4 ELEEVSPETPVVPATTQR 18 0 Q15149 Q15149 PLEC Plectin 1 0 ELEEVS(0.974)PET(0.026)PVVPATTQR;ELEEVS(0.991)PET(0.009)PVVPATTQR;ELEEVS(1)PETPVVPATTQR;ELEEVS(0.763)PET(0.237)PVVPATTQR ;;; 257.46 3.45E-42 154806700 9858.8 7995.6 9062.6 9176.9 9662.6 10746.8 7938.7 8268.86 8705.81 8592.9 TRUE FALSE FALSE 9078.465577 8686.704036 9398.467928 9138.928419 9547.379806 8517.792539 8161.438556 10789.99735 7750.804424 8891.502635 1.021027148 0.97696693 1.05701683 1.027827218 1.073764491 0.957969973 0.917891935 1.213517871 0.871709175 1 13.11821154 -4.244727749 24.64258718 1.008439105 1.213518067 0.526894159 0.061371229 1274.088506 1878706.844 0.00584344 0.218310971 5.69E-05 4.244727749 0.205078962 ELEEVSPET(ph)PVVPATTQR ddPTM_HeLa_Curcumin_4h_R1 1 ELEEVSPETPVVPATTQR 18 0 Q15149 Q15149 PLEC Plectin 1 0 ELEEVS(0.009)PET(0.991)PVVPATTQR 158.45 2.21E-09 0 1112.8 794.02 972.59 955.43 990.82 1691.3 1371.4 562.82 804.35 619.45 TRUE FALSE FALSE 1024.720706 862.6515507 1008.635041 951.4766838 979.0051186 1340.505315 1409.877793 734.4212271 716.1148174 640.9758414 1.598688499 1.345840974 1.573592912 1.484418947 1.527366642 2.091350763 2.199580237 1.145786127 1.11722591 1 9.324126172 -10.96443829 0.183661658 4.94E-16 1.854662149 0.39149494 0.291905812 15.00771037 0.412294508 6.67845528 0.476327512 1.09E-11 10.96443829 1.854662149 ELEEWYAR ddPTM_HeLa_Curcumin_4h_R1 2 ELEEWYAR 8 0 P09496-2;P09496-4;P09496-3;P09496;F8WF69;P09496-5;C9J8P9 P09496-2 CLTA Clathrin light chain A 0 0 ; ; 117.4 0.0089107 3020600 4185.5 3610.5 3551.9 3710 3337.1 4799.3 3855.3 3391.5 3832.2 3402.7 FALSE FALSE TRUE 3854.213258 3922.575532 3683.536539 3694.649003 3297.307262 3803.871081 3963.469342 4425.552737 3411.817248 3520.943572 1.094653515 1.114069411 1.046178805 1.049334909 0.936483984 1.080355593 1.125683858 1.25692237 0.969006512 1 11.78174639 -4.379238397 1.932118017 1.044829475 1.290917875 0.629783069 0.052533251 0.320403937 1.500196687 0.007711942 0.128332944 4.18E-05 4.379238397 0.246088399 ELEK(ac)VCNPIITK ddPTM_HeLa_Curcumin_4h_R1 1 ELEKVCNPIITK 12 1 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 1 ELEK(1)VCNPIITK 185.27 9.41E-10 1655600 544.18 502.36 336.32 456.05 386.14 488.89 543.22 283.15 527.69 412.59 FALSE TRUE FALSE 501.1075788 545.7817599 348.7843151 454.1629859 381.5355327 387.4887031 558.4612912 369.4811315 469.8037272 426.9274718 1.173753417 1.278394566 0.816963859 1.063794241 0.893677634 0.907621853 1.308094063 0.86544239 1.100429835 1 8.737847189 -6.758894128 24.99999588 1.099068621 0.988180481 0.206743754 0.14677007 116.7959996 1147185.877 0.02378158 0.032747477 1.74E-07 6.758894128 -0.11088814 ELEKPIQSKPQS(ph)PVIQAAAVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 ELEKPIQSKPQSPVIQAAAVSPK 23 2 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 2 0 ELEKPIQS(0.029)KPQS(0.974)PVIQAAAVS(0.997)PK;ELEKPIQS(0.09)KPQS(0.992)PVIQAAAVS(0.918)PK ; 84.509 0.00029049 46863000 5978.1 4760.7 5296.1 6099.7 5262.5 5865.7 5055.6 5028.5 6845.3 7424.1 TRUE FALSE FALSE 5504.927077 5172.193695 5492.378125 6074.461058 5199.748125 4649.0877 5197.44653 6561.666502 6094.387716 7682.086922 0.716592657 0.673279767 0.714959122 0.790730581 0.676866609 0.605185511 0.676567003 0.854151556 0.793324493 1 12.90728257 -9.103625153 0.647964626 1.025129836 0.704578847 0.296426869 0.090661539 0.36888537 0.251643149 0.065995281 0.014847121 7.88E-10 9.103625153 -0.320550989 ELEKPIQSKPQS(ph)PVIQAAAVSPK ddPTM_HeLa_Curcumin_4h_R1 1 ELEKPIQSKPQSPVIQAAAVSPK 23 2 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 0 ELEKPIQSKPQS(0.545)PVIQAAAVS(0.455)PK 86.189 0.00024213 44086000 3121.2 2502.2 2808.2 3569 2793.2 2427.2 2142.2 961.96 3426.6 3102.9 TRUE FALSE FALSE 2874.153727 2718.479018 2912.274362 3554.232424 2759.892914 1923.77136 2202.304367 1255.257176 3050.710553 3210.725544 0.89517266 0.846686825 0.907045564 1.106987307 0.859585435 0.599170291 0.685921091 0.390957482 0.950162358 1 11.64868363 -5.281145517 2.825171244 0.948179271 0.555883912 0.779187315 0.093729401 0.095093284 1.507634902 0.013652844 0.036795258 5.23E-06 5.281145517 -0.392295359 ELEKPIQSKPQSPVIQAAAVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 ELEKPIQSKPQSPVIQAAAVSPK 23 2 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 0 ELEKPIQSKPQSPVIQAAAVS(1)PK 139.22 1.16E-05 37073000 1528 1582.5 1646.6 1718 1562.2 1600.2 1023 598.46 1839.1 1748.5 TRUE FALSE FALSE 1407.057188 1719.284249 1707.624444 1710.891371 1543.571785 1268.300482 1051.702627 780.927699 1637.355331 1809.260245 0.77769751 0.95026918 0.943824665 0.945630335 0.853150778 0.701005002 0.58128875 0.431628176 0.904986077 1 10.82118423 -4.827293637 1.320390073 0.905135862 0.418358961 0.892036759 0.057977961 0.206857986 0.56172841 0.0130026 0.102337813 1.49E-05 4.827293637 -0.486776901 ELEQHIQTS(ph)DPENFQSEER ddPTM_HeLa_Curcumin_4h_R1 2 ELEQHIQTSDPENFQSEER 19 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 0 ELEQHIQT(0.242)S(0.757)DPENFQS(0.001)EER;ELEQHIQT(0.227)S(0.77)DPENFQS(0.003)EER ; 110.33 0.00022779 49124000 8406 7292.5 7150.5 7448.5 8099.2 8921.8 7432.3 6556.2 8135 6945 TRUE FALSE FALSE 7740.65623 7922.831205 7415.50382 7417.680081 8002.62233 7071.318111 7640.830335 8555.155199 7242.610853 7186.338233 1.077134972 1.102485153 1.031889062 1.032191895 1.113588321 0.983994613 1.063243906 1.190474887 1.0078305 1 12.81104112 -13.52287875 0.24386778 0.558479748 1.079389518 0.227047996 0.052505126 54.79557287 0.719251276 11.60752106 0.032549345 3.00E-14 13.52287875 0.52090977 ELEQHIQTSDPENFQS(ph)EERSDSDVNNDR ddPTM_HeLa_Curcumin_4h_R1 1 ELEQHIQTSDPENFQSEERSDSDVNNDR 28 1 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 0 ELEQHIQT(0.016)S(0.066)DPENFQS(0.323)EERS(0.323)DS(0.272)DVNNDR 49.57 0.006987 5926600 3723.5 3140.6 3027.6 3573.9 3660.3 3692 3522.3 3152 3538.5 3674.2 TRUE FALSE FALSE 3428.781046 3412.05947 3139.805519 3559.112149 3616.653313 2926.237583 3621.126258 4113.03029 3150.335403 3801.878177 0.901865048 0.897466808 0.825856425 0.936145764 0.951280695 0.769682101 0.952457204 1.081841684 0.828626078 1 11.89249659 -9.151843934 0.918980395 0.999648811 0.909652288 0 0.09410479 0.853980394 1.307457346 0.050231419 0.014677473 7.05E-10 9.151843934 -0.089996523 ELEQS(ph)QKEAS(ph)DLLEQNR ddPTM_HeLa_Curcumin_4h_R1 1 ELEQSQKEASDLLEQNR 17 1 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 2 0 ELEQS(1)QKEAS(1)DLLEQNR 42.52 0.018436 8952000 2005.7 1409.5 1508 1711.2 1515 1654.9 1331.9 735.04 1851 1723.5 TRUE FALSE FALSE 1846.946729 1531.330899 1563.887807 1704.119508 1496.934614 1311.655085 1369.269529 959.1503123 1647.949931 1783.391497 1.035637285 0.858662219 0.876917833 0.955549867 0.839375211 0.735483537 0.767789648 0.537823756 0.924053935 1 10.80040773 -3.60794384 0.349227223 1.022919253 5.34E-15 0.792385673 0.063091435 2.471948135 0.149723946 0.018736717 1.167972019 0.000246636 3.60794384 -1.022919253 AQQELVPPQQQAS(ph)PPQLPK ddPTM_HeLa_Curcumin_4h_R1 1 AQQELVPPQQQASPPQLPK 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 AQQELVPPQQQAS(1)PPQLPK 68.303 0.0053834 40336000 5186.6 4101.5 4385.8 5034 4349.6 4739.2 3043.2 1856.1 5490.3 4742.5 TRUE FALSE FALSE 4776.075137 4456.015384 4548.341606 5013.170642 4297.733861 3756.236498 3128.584002 2422.016346 4888.027826 4907.301522 0.973258952 0.908037822 0.926851873 1.021573796 0.875783532 0.765438293 0.637536534 0.493553603 0.996072445 1 12.2607142 -4.706557216 0.905998565 0.981126794 0.390423001 0.951654707 0.036580713 0.17915477 0.166003494 0.006077715 0.089198007 1.97E-05 4.706557216 -0.590703793 down ELESQISELQEDLESER ddPTM_HeLa_Curcumin_4h_R1 2 ELESQISELQEDLESER 17 0 P35579 P35579 MYH9 Myosin-9 0 0 ; ; 439.47 0 58068000 3132.3 3245.8 2968.7 3115.7 3668.1 3301.2 2943.1 2797.2 2964.7 2465.6 FALSE FALSE TRUE 2884.37515 3526.352489 3078.722634 3102.808059 3624.360303 2616.493908 3025.675465 3650.053403 2639.479827 2551.279416 1.130560272 1.38218984 1.206736751 1.216177279 1.420605003 1.025561485 1.185944372 1.430675676 1.034571051 1 11.3170052 -7.835121369 1.241756191 1.033344719 1.255485407 0.391019145 0.120411208 0.288593048 0.9310413 0.027664856 0.025138222 1.46E-08 7.835121369 0.222140688 ELEVQHPAAK ddPTM_HeLa_Curcumin_4h_R1 2 ELEVQHPAAK 10 0 P50990-2;P50990;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 0 0 ; ; 92.611 0.013954 11140900 12990.8 10607.5 11215.1 11355.3 11172.1 12927.5 10404 9498.7 12316.9 11399.1 FALSE FALSE TRUE 11962.56447 11524.36503 11630.74147 11308.31478 11038.88 10246.19078 10695.90824 12394.8099 10965.76689 11795.21788 1.014187665 0.977037063 0.98605567 0.958720296 0.935877584 0.868673295 0.906800396 1.050833485 0.929679045 1 13.52591445 -6.353652725 1.433440541 1.005512087 0.934011955 0.04388542 0.050195337 0.338429701 1.368840294 0.007212307 0.01293266 4.43E-07 6.353652725 -0.071500131 ELFDDPS(ph)YVNVQNLDK ddPTM_HeLa_Curcumin_4h_R1 1 ELFDDPSYVNVQNLDK 16 0 Q5T188;H0Y539;X6R6D0;P29353-5;P29353-3;P29353-2;P29353-7;P29353;P29353-6 Q5T188 SHC1 SHC-transforming protein 1 1 0 ELFDDPS(0.768)Y(0.232)VNVQNLDK 254.89 3.36E-40 46535000 3737.5 4175.1 3841.4 3349.9 3483.1 5379.8 2276 3667.8 6634.1 3706.3 TRUE FALSE FALSE 3441.672931 4535.97704 3983.765663 3336.039001 3441.566307 4263.968837 2339.858434 4786.095336 5906.355828 3835.093649 0.897415616 1.182755222 1.038766202 0.869871588 0.897387814 1.11182913 0.610117679 1.247973524 1.540081252 1 11.90504609 -6.264542051 24.57953071 0.977290919 0.93504855 0 0.246990561 1052.109207 8334862.515 0.024300109 0.038135999 5.44E-07 6.264542051 -0.042242369 ELFDDPSY(ph)VNVQNLDK ddPTM_HeLa_Curcumin_4h_R1 1 ELFDDPSYVNVQNLDK 16 0 Q5T188;H0Y539;X6R6D0;P29353-5;P29353-3;P29353-2;P29353-7;P29353;P29353-6 Q5T188 SHC1 SHC-transforming protein 1 1 0 ELFDDPS(0.048)Y(0.952)VNVQNLDK 134.25 0.0020498 13337000 5479.2 6708.3 6585.4 4803.2 4638.7 7966.6 3535.5 5347.3 10785 5881.3 TRUE FALSE FALSE 5045.515538 7288.13556 6829.460717 4783.325631 4583.386532 6314.237358 3634.696615 6977.667154 9601.912483 6085.674737 0.829080711 1.197588743 1.122219148 0.785997582 0.753143526 1.037557482 0.597254499 1.146572476 1.5777893 1 12.57120151 ELFQT(ph)PCTDNPTTDEK ddPTM_HeLa_Curcumin_4h_R1 1 ELFQTPCTDNPTTDEK 16 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 ELFQT(0.852)PCT(0.148)DNPTTDEK 166.9 0.00052649 15526000 1325.2 1152.4 1380.1 1870.6 1480 3178.6 2624.2 884.39 1829 1103.4 TRUE FALSE FALSE 1220.309022 1252.008321 1431.24772 1862.859953 1462.351967 2519.32253 2697.827989 1154.03644 1628.363276 1141.743068 1.068812289 1.096576241 1.253563749 1.631592961 1.280806521 2.206558201 2.362902885 1.010767196 1.426208156 1 10.15702232 -6.105367737 1.056363726 1.029774428 1.855357997 0.31250829 0.3862042 0.309025915 0.680071658 0.059307272 0.136632678 7.85E-07 6.105367737 0.825583569 ELFQT(ph)PGHTEEAVAAGK ddPTM_HeLa_Curcumin_4h_R1 4 ELFQTPGHTEEAVAAGK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 ELFQT(0.906)PGHT(0.094)EEAVAAGK;ELFQT(0.978)PGHT(0.022)EEAVAAGK;ELFQT(0.99)PGHT(0.01)EEAVAAGK;ELFQT(0.671)PGHT(0.329)EEAVAAGK ;;; 113.71 0.0008921 40379100 12410.4 9475.1 11493.1 15282.8 13941 28503 28169 6746.98 16309.1 10378.3 TRUE FALSE FALSE 11428.10374 10294.08542 11919.0444 15219.56382 13774.76268 22591.1565 28959.34633 8804.103143 14520.03253 10738.94515 1.06417377 0.9585751 1.10988968 1.417230799 1.282692339 2.103666253 2.696665819 0.819829417 1.352091134 1 13.39056467 -5.613599913 1.757829823 1.039345193 1.934925718 0.30643014 0.461996973 0.239529036 1.48135945 0.062671662 0.159349442 2.43E-06 5.613599913 0.895580525 ELFQT(ph)PGHTEELVAAGK ddPTM_HeLa_Curcumin_4h_R1 1 ELFQTPGHTEELVAAGK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 ELFQT(0.976)PGHT(0.024)EELVAAGK 180.93 2.15E-05 9623200 2883.2 2157 2765.9 3544.3 3455.8 6107.6 6043.9 1381.1 3501.4 2458.7 TRUE FALSE FALSE 2654.991678 2343.441469 2868.406687 3529.634626 3414.591842 4840.814913 6213.475568 1802.191032 3117.30518 2544.139642 1.043571522 0.921113539 1.127456465 1.387358841 1.342140103 1.902731608 2.44226986 0.708369542 1.225288553 1 11.31296214 -5.873608887 1.47726136 1.0163399 1.730346535 0.272554515 0.41444098 0.29968048 1.313490925 0.05937642 0.136654873 1.34E-06 5.873608887 0.714006634 ELFQTPDHT(ph)EESTTDDKTTK ddPTM_HeLa_Curcumin_4h_R1 1 ELFQTPDHTEESTTDDKTTK 20 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 ELFQT(0.033)PDHT(0.878)EES(0.064)T(0.019)T(0.006)DDKTTK 96.562 0.00062022 31092000 2001.6 1621.8 1692.8 1872.4 1838.5 3218.8 3356.9 1162 2112.5 1998.7 TRUE FALSE FALSE 1843.171248 1761.981165 1755.536657 1864.652505 1816.577088 2551.184597 3451.085579 1516.288451 1880.764035 2068.154676 0.891215376 0.851958118 0.848842051 0.901602054 0.878356493 1.233555994 1.668678663 0.733160081 0.909392347 1 11.01412837 -5.240200568 9.110275171 0.924732793 1.258006605 0.296332401 0.215745448 0.275625517 110.4899262 0.027416449 0.068663957 5.75E-06 5.240200568 0.333273813 ELFQTPGHT(ph)EELVAAGK ddPTM_HeLa_Curcumin_4h_R1 2 ELFQTPGHTEELVAAGK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 ELFQT(0.003)PGHT(0.997)EELVAAGK;ELFQT(0.055)PGHT(0.945)EELVAAGK ; 83.776 0.0071052 17216100 5545.9 4304.4 4564.8 6322.8 6057.4 11371.4 12553.7 2820.71 6415.4 4587.5 TRUE FALSE FALSE 5106.936163 4676.453156 4733.975504 6296.637929 5985.169461 9012.843458 12905.92304 3680.731494 5711.646671 4746.915284 1.075843123 0.985156228 0.997274066 1.326469413 1.260854493 1.898673753 2.718802057 0.775394393 1.203233327 1 12.21277459 -5.44692186 2.434577532 1.046219249 1.887046199 0.313566061 0.452537409 0.204936253 2.371481139 0.059446036 0.149935923 3.57E-06 5.44692186 0.840826949 ELGITALHIK ddPTM_HeLa_Curcumin_4h_R1 2 ELGITALHIK 10 0 P62263;A0A2R8Y811;E5RH77 P62263 RPS14 40S ribosomal protein S14 0 0 ; ; 101.9 0.0025866 4285200 2605.1 1526.64 2138.37 1899.8 2194.3 4100.1 2794.7 2181.22 2076.71 2167.18 FALSE FALSE TRUE 2398.903586 1658.595959 2217.619873 1891.939131 2168.134406 3249.693042 2873.11176 2846.263937 1848.900109 2242.489344 1.069750272 0.739622671 0.988909882 0.843678092 0.966842679 1.449145367 1.281215346 1.269243016 0.824485572 1 11.13088541 -5.271885837 24.94369074 0.989324523 1.328002653 0.702084312 0.117533389 300.3157465 717083.7381 0.016317768 0.036859469 5.35E-06 5.271885837 0.33867813 ELGIWEPLAVK ddPTM_HeLa_Curcumin_4h_R1 1 ELGIWEPLAVK 11 0 P49368;B4DUR8;P49368-2 P49368 CCT3 T-complex protein 1 subunit gamma 0 0 120.68 5.92E-07 0 394.68 223.72 340.14 200.06 493.79 289.57 256.08 261.45 363.01 373.85 FALSE FALSE TRUE 363.4406615 243.0573599 352.7458876 199.2322047 487.9018768 229.5099179 263.2649156 341.1649014 323.1887112 386.8412597 0.939508526 0.628312916 0.911862111 0.515023152 1.261245704 0.593292241 0.680550249 0.881924802 0.835455637 1 8.595597868 -7.450241488 8.769565217 0.973454523 0.783524278 0.081808942 0.204231255 0.479548798 54.58903722 0.031247412 0.035585921 3.55E-08 7.450241488 -0.189930245 ELGLREENEGVYNGSWGGR ddPTM_HeLa_Curcumin_4h_R1 1 ELGLREENEGVYNGSWGGR 19 1 A0A0J9YWM6;A0A1B0GV49;A0A1B0GW82;A0A1B0GTG2;A0A1B0GUA1;A0A1B0GTJ4;A0A1B0GTY9;A0A1B0GW65;A0A1B0GW77;A0A1B0GUY0;A0A0J9YWF7;H0YHM6;F8VVF2;F8WDY6;F8WD33;P49419-2;P49419;P49419-4 A0A0J9YWM6 ALDH7A1 Alpha-aminoadipic semialdehyde dehydrogenase 0 0 76.068 0.0055185 7359000 1268.7 990.41 1108.3 964.78 925.79 1238.7 911.64 1004.6 1118 1108.5 FALSE FALSE TRUE 1168.281056 1076.016627 1149.374573 960.787996 914.7505589 981.779657 937.2181648 1310.897915 995.3581971 1147.020292 1.018535647 0.938097289 1.002052519 0.837638185 0.797501635 0.855939222 0.817089437 1.14287247 0.867777321 1 10.1636752 -6.274428298 23.4788876 1.002095199 0.879091844 0.0601526 0.102346293 316.1493119 571473.8618 0.013534204 0.02076771 5.32E-07 6.274428298 -0.123003355 ELGPLPDDDDMAS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 ELGPLPDDDDMASPK 15 0 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-7;Q86U86-3;Q86U86-2;Q86U86-4;Q86U86-9;H0Y5B5;Q86U86-6 Q86U86-8 PBRM1 Protein polybromo-1 1 0 ELGPLPDDDDMAS(1)PK;ELGPLPDDDDMAS(1)PK;ELGPLPDDDDMAS(1)PK;ELGPLPDDDDMAS(1)PK ;;; 244.05 3.16E-29 53503900 12443.8 10437.4 12223.9 12486.7 13342.1 14735.7 13967 5122.2 11633.7 10321.3 TRUE FALSE FALSE 11458.8601 11339.56235 12676.92849 12435.03334 13183.00417 11679.34971 14358.87643 6683.9352 10357.51222 10679.96441 1.072930551 1.061760313 1.186982279 1.164332845 1.2343678 1.093575715 1.344468566 0.625838715 0.969807747 1 13.38261922 -7.911217808 0.883911705 1.014640988 1.121498124 0.049476492 0.179106998 1.098660479 1.844523096 0.047456806 0.038394351 1.23E-08 7.911217808 0.106857137 ELGS(ph)PTDEDSGQDQQLLR ddPTM_HeLa_Curcumin_4h_R1 1 ELGSPTDEDSGQDQQLLR 18 0 H0Y713;Q86YN6-6;Q86YN6-5;Q86YN6-4;Q86YN6-2;Q86YN6-3;Q86YN6 H0Y713 PPARGC1B Peroxisome proliferator-activated receptor gamma coactivator 1-beta 1 0 ELGS(0.986)PT(0.014)DEDSGQDQQLLR 150.59 9.19E-05 4518400 954.69 787.54 794.24 951.43 844.21 1155.8 798.67 574.83 847.24 754.8 TRUE FALSE FALSE 879.1252791 855.6114484 823.6752331 947.4932348 834.1433471 916.0740514 821.0785307 750.0930208 754.2998917 781.0292438 1.125598415 1.095492205 1.054602295 1.213134133 1.068005268 1.172906212 1.051277577 0.960390442 0.965776759 1 9.609232758 -9.380929367 1.042461387 0.998560769 1.098201435 0.285509923 0.067188093 0.631735563 1.199767501 0.047342698 0.011488403 4.16E-10 9.380929367 0.099640666 ELHINLIPNK ddPTM_HeLa_Curcumin_4h_R1 1 ELHINLIPNK 10 0 P07900;P07900-2;G3V2J8;Q14568 P07900 HSP90AA1;HSP90AA2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2 0 0 77.662 0.013768 1779800 3746.9 3375.3 4820.1 3574.1 5195.1 5104 4084.6 3821.8 2591.8 2853.1 FALSE FALSE TRUE 3450.328911 3667.045892 4998.737146 3559.311321 5133.151826 4045.372866 4199.202883 4987.049227 2307.486024 2952.245013 1.168713605 1.242121124 1.693198608 1.205628702 1.738728257 1.370270031 1.422376146 1.689239614 0.781603835 1 11.52759674 -7.226864254 0.960764617 1.047468209 1.516557444 0.617086343 0.185331283 0.230199124 0.420382936 0.033755921 0.040890046 5.93E-08 7.226864254 0.469089235 ELHINLIPNKQDR ddPTM_HeLa_Curcumin_4h_R1 1 ELHINLIPNKQDR 13 1 P07900;P07900-2;G3V2J8 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 67.879 0.01015 34723000 6307.3 5531.3 6088.8 5822.4 6668 6914 5761.7 5599.6 5647 6174.2 FALSE FALSE TRUE 5808.07055 6009.400925 6314.456284 5798.308452 6588.488455 5479.958463 5923.357795 7306.892263 5027.538228 6388.75299 0.909108641 0.940621892 0.988370703 0.907580628 1.031263607 0.857750874 0.927153985 1.143711813 0.786935766 1 12.64131865 -4.257115826 24.74460939 0.950796138 1.143711901 0.426148753 0.070769641 218.9995249 1253325.313 0.006979944 0.073304911 5.53E-05 4.257115826 0.192915764 ELHIQGNR ddPTM_HeLa_Curcumin_4h_R1 1 ELHIQGNR 8 0 Q15404-2;Q15404 Q15404-2 RSU1 Ras suppressor protein 1 0 0 98.997 0.012484 5176700 4216.1 3611.4 4005.2 3732.5 3950 6003.9 4277.8 4284.2 4325.9 3836.2 FALSE FALSE TRUE 3882.391236 3923.553324 4153.636235 3717.055904 3902.89883 4758.623462 4397.823555 5590.432858 3851.359593 3969.507664 0.978053594 0.988423164 1.046385745 0.936402249 0.983219875 1.198794376 1.107901515 1.40834414 0.970236089 1 11.95474437 -1.000001371 0.631386659 0.987596233 33.46264375 0.843607269 0.054183566 46.31011906 0.296349296 0.008627992 2097.816796 0.099999684 1.000001371 32.47504752 ELHPQLLS(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 1 ELHPQLLSPTK 11 0 E9PK89;Q8TBN0 E9PK89 RAB3IL1 Guanine nucleotide exchange factor for Rab-3A 1 0 ELHPQLLS(0.975)PT(0.025)K 95.822 0.0064445 29439000 8145.3 6608.1 7775.7 6933.8 7038.7 8675.9 6766.7 4866.2 7443 7257.9 TRUE FALSE FALSE 7500.59091 7179.274719 8063.874282 6905.109773 6954.7681 6876.420542 6956.55539 6349.881979 6626.521521 7510.111485 0.998732299 0.955947822 1.073735629 0.919441714 0.926053909 0.915621633 0.926291894 0.845511014 0.882346625 1 12.87461861 -6.097762844 8.597923554 1.000486099 0.907952932 0.328993728 0.050925592 0.146881104 11.81239319 0.00473163 0.007862411 7.98E-07 6.097762844 -0.092533167 ELIEVDDVMEDDSLR ddPTM_HeLa_Curcumin_4h_R1 2 ELIEVDDVMEDDSLR 15 0 H0YI19;F8W1F4;Q9UHW5;Q9UHW5-2;Q9UHW5-3 H0YI19 GPN3 GPN-loop GTPase 3 0 0 ; ; 214.81 2.91E-13 3997500 1537.09 1490.73 1719.49 1581.73 1524.76 2065.09 1339.61 1736.63 1581.13 1455.57 FALSE FALSE TRUE 1415.427705 1619.582059 1783.215812 1575.18522 1506.578233 1636.767056 1377.195851 2266.120493 1407.683995 1506.150949 0.939764839 1.075311913 1.183955574 1.045834895 1.000283692 1.08672179 0.914381027 1.504577276 0.934623449 1 10.55665065 -4.255148695 24.91839643 1.003789026 1.50457751 0.767906688 0.079451013 250.2382329 991204.456 0.011624405 0.145355818 5.56E-05 4.255148695 0.500788484 ELILGS(ph)ETPSSPR ddPTM_HeLa_Curcumin_4h_R1 1 ELILGSETPSSPR 13 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 0 ELILGS(0.798)ET(0.12)PS(0.032)S(0.05)PR 136.01 0.0012499 21404000 4588.8 3381.1 4171.2 3645.6 4268.1 5361.5 4163 3309 4603.7 3547.6 TRUE FALSE FALSE 4225.591638 3673.347218 4325.788341 3630.515473 4217.205695 4249.464463 4279.802576 4317.898867 4098.685628 3670.878836 1.151111717 1.000672423 1.178406734 0.989004442 1.148827266 1.157615016 1.165879553 1.176257529 1.116540701 1 11.84190978 -13.52287875 0.210689743 0.39309716 1.146488534 0.05537039 0.072970208 42.10870456 0.523752561 10.60211242 0.057295637 3.00E-14 13.52287875 0.753391374 ELILGSETPSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 ELILGSETPSSPR 13 0 R4GNJ5;A0A590TQL1;Q96AP0-2;Q96AP0 R4GNJ5 ACD Adrenocortical dysplasia protein homolog 1 0 ELILGSET(0.002)PS(0.229)S(0.768)PR;ELILGS(0.002)ET(0.015)PS(0.273)S(0.71)PR;ELILGSETPS(0.071)S(0.928)PR ;; 207.31 4.18E-09 52534300 10189.3 8201.9 8683.3 9697 8798.6 12910.1 10444.5 5442.5 10206.3 10123.6 TRUE FALSE FALSE 9382.806153 8910.835689 9005.110737 9656.876383 8693.682442 10232.39973 10737.54456 7101.893196 9086.694425 10475.39435 0.895699564 0.850644414 0.85964408 0.921862802 0.829914574 0.976803297 1.025025331 0.677959508 0.867432206 1 13.35471693 -8.914540308 0.756145368 1.000424121 0.885893369 0 0.096738774 0.844022245 0.893953497 0.054577387 0.01757434 1.22E-09 8.914540308 -0.114530753 ELIPQES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 ELIPQESPR 9 0 Q96DF8 Q96DF8 DGCR14 Protein DGCR14 1 0 ELIPQES(1)PR 111.52 0.0086577 41676000 5311.4 4949.4 4385.2 4894.5 4667.8 5335.8 3685.4 3361.8 5159.2 4352.9 TRUE FALSE FALSE 4890.997085 5377.204082 4547.71937 4874.247856 4612.139534 4229.094933 3788.802405 4386.797344 4593.248668 4504.162951 1.08588369 1.193829828 1.009670258 1.082165079 1.023972619 0.938930269 0.841177916 0.97394286 1.019778529 1 12.13704331 -5.257714203 3.014492854 1.054179384 0.904624088 0.539230707 0.06053185 0.163029664 2.996978094 0.009259406 0.024971152 5.52E-06 5.257714203 -0.149555297 ELIPTEEALR ddPTM_HeLa_Curcumin_4h_R1 1 ELIPTEEALR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 159.28 0.0052729 2692800 1921.5 1453.4 1669.2 1876.7 1908.3 2120.3 1538.1 1488.3 1875.7 1625.3 FALSE FALSE TRUE 1769.411247 1579.02542 1731.06202 1868.934713 1885.544769 1680.525879 1581.254946 1942.075819 1669.940403 1681.779054 1.052106841 0.938901823 1.029304067 1.111284332 1.121160811 0.999254852 0.940227518 1.15477465 0.992960638 1 10.71577247 -13.52287874 0.171114055 0.833346584 1.054439822 0.089768762 0.067725317 155.7295668 1.734634071 8.777314838 0.109508726 3.00E-14 13.52287874 0.221093238 ELIQK(ac)ELTIGSK ddPTM_HeLa_Curcumin_4h_R1 1 ELIQKELTIGSK 12 1 R4GN98;P06703 R4GN98 S100A6 Protein S100;Protein S100-A6 0 1 ELIQK(1)ELTIGSK 210.93 6.98E-21 774390 392.19 301.05 279.39 270.21 327.47 399.63 356.71 242.29 372.32 249.71 FALSE TRUE FALSE 361.1477477 327.0714205 289.7444392 269.0919426 323.5651341 316.7422332 366.7183226 316.1631056 331.4774275 258.3874039 1.397698735 1.265817976 1.121356671 1.041428253 1.252248094 1.225842392 1.419257739 1.223601077 1.282869917 1 8.013391932 -9.556383816 1.337611612 1.000464948 1.259112333 0 0.136675235 0.362868014 1.166699394 0.08411792 0.020009714 2.78E-10 9.556383816 0.258647384 ELISNASDALDK ddPTM_HeLa_Curcumin_4h_R1 2 ELISNASDALDK 12 0 P14625;Q96GW1;A0A1W2PRR1;F8W026;P08238 P14625;P08238 HSP90B1;HSP90AB1 Endoplasmin;Heat shock protein HSP 90-beta 0 0 ; ; 237.76 1.70E-39 22795200 10160.1 9101.7 9977.7 9752.6 11221.3 11812.2 9546.2 9634.5 8442.6 8053.7 FALSE FALSE TRUE 9355.917364 9888.410392 10347.48234 9712.246325 11087.49333 9362.216569 9814.04068 12572.0147 7516.467902 8333.565476 1.122678809 1.186576192 1.241663292 1.165437093 1.330462136 1.123434693 1.177652076 1.508599739 0.901951023 1 13.02471816 -1.000000013 0.070371406 0.726606947 2.293750349 0.628409515 0.096518992 116.4853462 0.61104006 2.418392594 18.17155934 0.099999997 1.000000013 1.567143402 ELISNSSDALDK ddPTM_HeLa_Curcumin_4h_R1 5 ELISNSSDALDK 12 0 P07900;P07900-2;G3V2J8;Q14568 P07900 HSP90AA1;HSP90AA2P Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2 0 0 ;;;; ;;;; 240.8 8.56E-50 79196000 16787.1 14945.8 15868 15743.3 17478.4 18400.4 15563.5 14251.28 14821.2 13700.63 FALSE FALSE TRUE 15458.38332 16237.64835 16456.08204 15678.1584 17269.9815 14583.94962 16000.16992 18596.42967 13195.35144 14176.72587 1.090405744 1.145373657 1.160781565 1.105908271 1.218192526 1.02872481 1.128622368 1.311757724 0.930775664 1 13.79123676 -13.52287842 0.048134605 0.308792383 1.496653317 0.547314858 0.069848234 288.9229998 1.103475208 26.38902414 6.854149024 3.00E-14 13.52287842 1.187860934 ELISNSSDALDK(ac)IR ddPTM_HeLa_Curcumin_4h_R1 1 ELISNSSDALDKIR 14 1 P07900;P07900-2;G3V2J8 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 1 ELISNSSDALDK(1)IR 217.12 5.02E-27 1255700 221.56 209.9 236.55 105.84 351.47 425.33 251.32 279.74 344.52 216.44 FALSE TRUE FALSE 204.0232922 228.0428207 245.3167511 105.4020621 347.2789498 337.1117635 258.3713628 365.0314382 306.7270179 223.9612739 0.910975762 1.018224342 1.095353437 0.470626284 1.550620533 1.50522346 1.153643031 1.629886417 1.369553819 1 7.807105481 -5.729283765 24.99999918 0.942994692 1.441213604 0.489918663 0.239289436 94.68164142 73611.60988 0.026344521 0.052685648 1.87E-06 5.729283765 0.498218912 ELISNSSDALDKIR ddPTM_HeLa_Curcumin_4h_R1 2 ELISNSSDALDKIR 14 1 P07900;P07900-2;G3V2J8 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 ; ; 141.34 0.00063268 78902000 2892.5 1996.58 2481.5 2664.4 2240.12 3196.7 2413 2029.03 2705 2057.01 FALSE FALSE TRUE 2663.555573 2169.155479 2573.466573 2653.375419 2213.408032 2533.668386 2480.702286 2647.671906 2408.268268 2128.490944 1.251382149 1.019104866 1.209056858 1.246599346 1.039895442 1.190359016 1.165474672 1.243919742 1.131443981 1 11.05561524 -9.503622363 1.192960215 0.997914365 1.175106347 0.125465671 0.086666592 0.380125129 0.949548564 0.056430822 0.01300553 3.14E-10 9.503622363 0.177191982 ELK(ac)ELIQK ddPTM_HeLa_Curcumin_4h_R1 2 ELKELIQK 8 1 R4GN98;P06703 R4GN98 S100A6 Protein S100;Protein S100-A6 0 1 ; ELK(1)ELIQK;ELK(1)ELIQK 145.17 0.00039619 4469500 2977.7 2926.4 2174.95 3034.1 2656.4 4665.9 3890.9 3623.2 5628.3 3312.5 FALSE TRUE FALSE 2742.011903 3179.344976 2255.55556 3021.545698 2624.724165 3698.139744 4000.068182 4727.897001 5010.889571 3427.609128 0.799978002 0.927569293 0.658055069 0.881531582 0.765759474 1.078926915 1.1670141 1.379357104 1.461919777 1 11.74298688 -4.728231011 1.717360562 0.876917421 1.366517834 0.289731944 0.210026139 0.200856937 1.001958138 0.016622654 0.120105868 1.87E-05 4.728231011 0.489600413 ELKELIQK ddPTM_HeLa_Curcumin_4h_R1 1 ELKELIQK 8 1 R4GN98;P06703 R4GN98 S100A6 Protein S100;Protein S100-A6 0 0 80.239 0.0095694 0 5702.4 3879.4 3139.9 5199.7 2069.2 6389.2 4043.1 4415.8 9200.1 7727.4 FALSE FALSE TRUE 5251.049023 4214.71805 3256.267456 5178.185019 2044.526141 5064.007899 4156.538505 5762.157092 8190.872048 7995.926575 0.656715513 0.527108148 0.40724079 0.647602873 0.255695962 0.633323462 0.519832 0.720636569 1.024380598 1 12.96504951 -8.457181131 0.652536274 0.98962018 0.52039243 0.678642513 0.128431234 0.299623587 0.266699319 0.066933913 0.03039799 3.49E-09 8.457181131 -0.46922775 ELKTDSS(ph)PNQAR ddPTM_HeLa_Curcumin_4h_R1 2 ELKTDSSPNQAR 12 1 A6NLN1;P26599;P26599-2;P26599-3;K7ES59;A0A087WU68 A6NLN1 PTBP1 Polypyrimidine tract-binding protein 1 1 0 ELKT(0.004)DS(0.032)S(0.964)PNQAR;ELKT(0.003)DS(0.095)S(0.901)PNQAR ; 159.58 0.0022277 137685000 7710.5 5348 6297 6761.6 5151.9 8049.3 5944.2 4960.1 8183 6314.9 TRUE FALSE FALSE 7100.205789 5810.25729 6530.372359 6733.622291 5090.466957 6379.784446 6110.978254 6472.411657 7285.345373 6534.342305 1.086598384 0.889187774 0.999392449 1.030497329 0.779032796 0.976346838 0.935209386 0.990522283 1.1149317 1 12.67382632 -7.264373534 24.95846628 1.040893681 0.943117129 0.36300746 0.073000751 237.1828575 2017515.801 0.011944218 0.01398795 5.44E-08 7.264373534 -0.097776552 AMSTTSISSPQPGK(ac)LR ddPTM_HeLa_Curcumin_4h_R1 2 AMSTTSISSPQPGKLR 16 1 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 0 1 ; AMSTTSISSPQPGK(1)LR;AMSTTSISSPQPGK(1)LR 244.73 3.98E-48 8162200 789.86 654.38 785.09 834.22 622.3 1081.86 1219.24 4524 1109.62 633.16 FALSE TRUE FALSE 727.3417475 710.9416913 814.186126 830.7682187 614.8794789 857.4700409 1253.448593 5903.346774 987.8974621 655.1622629 1.110170394 1.085138341 1.242724394 1.268034296 0.938514798 1.30879034 1.913188021 9.010510996 1.507866857 1 9.35570845 -4.250615093 3.3867654 1.097055898 10.14061331 0.994311077 0.176443943 0.013651751 0.254618765 0.020897246 0.322369676 5.62E-05 4.250615093 9.043557414 up ELLAVPDNYK ddPTM_HeLa_Curcumin_4h_R1 2 ELLAVPDNYK 10 0 Q9Y617;Q9Y617-2 Q9Y617 PSAT1 Phosphoserine aminotransferase 0 0 ; ; 99.815 0.01117 3102200 5060.3 4498.9 4720 5077.2 4934.7 5213.1 4543.2 4078.9 5203 4586.6 FALSE FALSE TRUE 4659.771915 4887.764869 4894.927352 5056.191892 4875.856925 4131.844296 4670.669965 5322.537833 4632.243917 4745.984009 0.981834727 1.02987386 1.031383027 1.065362185 1.027364803 0.870598023 0.984130995 1.121482463 0.976034455 1 12.21249152 -4.258231404 24.24552058 0.99539576 1.121482533 0.363556239 0.04968146 173.1275075 1308376.344 0.006888279 0.065962839 5.52E-05 4.258231404 0.126086773 ELLDTS(ph)FEDLSKPK ddPTM_HeLa_Curcumin_4h_R1 1 ELLDTSFEDLSKPK 14 1 P78345 P78345 RPP38 Ribonuclease P protein subunit p38 1 0 ELLDT(0.095)S(0.905)FEDLSKPK 204.28 4.60E-08 34077000 1459.9 1740.6 1577.7 1752.1 1837.7 1592.5 1401.3 680.93 1498.5 1515.1 TRUE FALSE FALSE 1344.347375 1891.049708 1636.17095 1744.850274 1815.786628 1262.197549 1440.616707 888.5424224 1334.118299 1567.749612 0.857501328 1.206219216 1.043643026 1.11296489 1.158212136 0.80510149 0.918907391 0.566762967 0.850976641 1 10.61447945 -3.89382567 1.330539245 0.983113084 2.36E-10 0.513985096 0.127404684 2.191425262 1.747964728 0.019784951 3.686167825 0.000127695 3.89382567 -0.983113084 ELLIFNK ddPTM_HeLa_Curcumin_4h_R1 1 ELLIFNK 7 0 P09874 P09874 PARP1 Poly [ADP-ribose] polymerase 1 0 0 104.11 0.017764 819090 209.07 259.25 251.66 193.07 249.86 135.25 166.93 201.52 236.49 161.44 FALSE FALSE TRUE 192.5218889 281.6584148 260.986741 192.2711275 246.8805827 107.1976254 171.6136065 262.9625203 210.5476387 167.050028 1.152480435 1.68607224 1.562326832 1.150979319 1.477884115 0.641709712 1.027318634 1.574154303 1.260386731 1 7.384136414 -7.686929448 3.132661298 1.057178371 1.283886823 0.039192802 0.301504373 0.404598195 8.342426297 0.057536326 0.058877373 2.06E-08 7.686929448 0.226708452 ELLIHER ddPTM_HeLa_Curcumin_4h_R1 1 ELLIHER 7 0 Q96BN8 Q96BN8 OTULIN Ubiquitin thioesterase otulin 0 0 98.629 0.016406 3843200 2700.9 1994.5 2204.2 2389.3 2513.1 2739.7 1831.6 1812.2 2412.8 2305.7 FALSE FALSE TRUE 2487.120915 2166.895693 2285.889591 2379.41371 2483.132924 2171.455337 1882.989767 2364.731438 2148.121877 2385.822903 1.042458311 0.908238281 0.958113692 0.997313634 1.040786774 0.910149422 0.789241215 0.991159668 0.900369375 1 11.22027124 -5.139261665 5.209488448 1.006404308 0.881439521 0.150545652 0.068218226 0.150345053 5.775694501 0.008253231 0.021715537 7.26E-06 5.139261665 -0.124964787 ELLLQPVTISR ddPTM_HeLa_Curcumin_4h_R1 2 ELLLQPVTISR 11 0 H7C0A3;F8WCF6;P59998;P59998-3;F8WDD7;A0A0A6YYG9;P59998-2 H7C0A3 ARPC4-TTLL3;ARPC4 Actin-related protein 2/3 complex subunit 4 0 0 ; ; 144.55 1.90E-05 5113800 2948.8 2972 2883.9 2745.8 2267.5 3320.1 3054.2 2501.9 2966.6 3411.5 FALSE FALSE TRUE 2715.399368 3228.886437 2990.779871 2734.438607 2240.461543 2631.473835 3139.892632 3264.717793 2641.171402 3530.049371 0.76922419 0.914685914 0.847234573 0.774617667 0.634682779 0.745449584 0.889475557 0.924836298 0.748196732 1 11.78547265 -9.429521501 0.753171097 1.02450279 0.805309894 0 0.114601712 0.765263244 0.630298205 0.109774755 0.017983107 3.72E-10 9.429521501 -0.219192895 ELLQFK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 ELLQFKK 7 1 Q8IYH5-2;Q8IYH5;Q8IYH5-3 Q8IYH5-2 ZZZ3 ZZ-type zinc finger-containing protein 3 0 1 ; ELLQFK(1)K;ELLQFK(1)K 124.08 0.0030723 4825000 4888.2 3564.8 3750.7 3628.5 3510.6 4848.5 3505.7 2629.7 4448.3 4166.6 FALSE TRUE FALSE 4501.293812 3872.925428 3889.704241 3613.486228 3468.738388 3842.866446 3604.060507 3431.483424 3960.332619 4311.38904 1.044047236 0.898301079 0.902192821 0.838125763 0.804552397 0.891329085 0.835939525 0.795911339 0.918574636 1 12.07393704 -6.953157842 1.752516451 1.021093819 0.838620688 0.636734278 0.046118509 0.089354227 0.546746615 0.006092115 0.008156586 1.11E-07 6.953157842 -0.182473131 ELLS(ph)PLSEPDDRYPLIVK ddPTM_HeLa_Curcumin_4h_R1 1 ELLSPLSEPDDRYPLIVK 18 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 0 ELLS(0.885)PLS(0.113)EPDDRY(0.002)PLIVK 77.357 0.003447 4330600 1677.8 1961.7 1841.1 1715 1748.7 2060.1 1767.1 2145 1731.3 1417.7 TRUE FALSE FALSE 1545.00036 2131.260607 1909.332786 1707.903784 1727.847895 1632.812038 1816.68007 2799.000626 1541.380721 1466.964969 1.053195129 1.452836742 1.301553088 1.16424306 1.177838551 1.113054553 1.238393628 1.908021448 1.050727695 1 10.51861871 ELLSPLS(ph)EPDDRYPLIVK ddPTM_HeLa_Curcumin_4h_R1 2 ELLSPLSEPDDRYPLIVK 18 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 0 ELLS(0.001)PLS(0.999)EPDDRYPLIVK;ELLS(0.001)PLS(0.999)EPDDRYPLIVK ; 119.87 0.00016151 244910000 4872.1 4141.9 4261.4 4515.3 4614.6 5644 3753.2 2996.15 5374.6 4473.7 TRUE FALSE FALSE 4486.468144 4499.90738 4419.331233 4496.616885 4559.573909 4473.370779 3858.504691 3909.662342 4785.019827 4629.160742 0.969175277 0.972078446 0.954672235 0.971367627 0.984967722 0.96634596 0.833521432 0.844572604 1.033668972 1 12.17653494 -4.787683411 5.445912168 0.980321078 0.837807653 0.882472331 0.020828848 0.028792673 2.344522766 0.002274058 0.007541611 1.63E-05 4.787683411 -0.142513425 ELLTLDEK(ac)DPR ddPTM_HeLa_Curcumin_4h_R1 1 ELLTLDEKDPR 11 1 P46781;B5MCT8;C9JM19;F2Z3C0;A8MXK4 P46781 RPS9 40S ribosomal protein S9 0 1 ELLTLDEK(1)DPR 115.18 0.0028494 4450000 1186.5 1877.2 1123.7 1234.8 2220.6 2875.1 2175.5 2140.3 3329.2 1185.9 FALSE TRUE FALSE 1092.587273 2039.456803 1165.345311 1229.690725 2194.120795 2278.771851 2236.538675 2792.867617 2963.995089 1227.109937 0.890374399 1.662000072 0.949666591 1.002103143 1.788039302 1.857023387 1.822606604 2.275971805 2.415427502 1 10.26104879 -5.205826553 0.586162872 0.95955607 2.411017699 0.056984945 0.523787192 0.566830258 0.244236581 0.050567692 0.455298986 6.23E-06 5.205826553 1.45146163 ELLTSDSPPHNDIMT(ph)PVDPGVAQPNSR ddPTM_HeLa_Curcumin_4h_R1 1 ELLTSDSPPHNDIMTPVDPGVAQPNSR 27 0 Q12778 Q12778 FOXO1 Forkhead box protein O1 1 0 ELLT(0.006)S(0.007)DS(0.036)PPHNDIMT(0.948)PVDPGVAQPNS(0.003)R 59.561 0.0042607 11256000 1294.2 905.77 957.53 1041.6 1186.8 1415.9 1058.5 707.27 1155.8 871.23 TRUE FALSE FALSE 1191.762704 984.0607228 993.0169041 1037.290135 1172.648185 1122.22638 1088.198661 922.9133671 1029.011632 901.5051777 1.321969894 1.091575231 1.101509929 1.150620275 1.300767 1.244836311 1.207090861 1.023747162 1.141437295 1 9.816191967 -5.957950948 24.99459405 1.146052441 1.20203991 0.069300234 0.10032136 458.6504986 272627.0177 0.020048919 0.036341724 1.10E-06 5.957950948 0.055987469 ELLTT(ph)MGDRFTDEEVDELYR ddPTM_HeLa_Curcumin_4h_R1 1 ELLTTMGDRFTDEEVDELYR 20 1 J3QRS3;P19105;O14950 J3QRS3 MYL12A;MYL12B Myosin regulatory light chain 12A;Myosin regulatory light chain 12B 1 0 ELLT(0.194)T(0.703)MGDRFT(0.104)DEEVDELYR 56.819 0.012086 20788000 3129.4 2732.4 2887.1 2882.8 3019.3 3474 2040.7 1417.6 3322.6 2907.5 TRUE FALSE FALSE 2881.704688 2968.576481 2994.098466 2870.871737 2983.296819 2753.45324 2097.95655 1849.819714 2958.119093 3008.535409 0.957843035 0.986718146 0.995201339 0.954242297 0.991611005 0.915213839 0.697334837 0.614857219 0.983242239 1 11.55484562 -4.742421939 2.395350835 0.980110046 0.618472063 0.986880049 0.014929117 0.027591374 0.301956803 0.002651136 0.013626421 1.81E-05 4.742421939 -0.361637983 ELLTTMGDR ddPTM_HeLa_Curcumin_4h_R1 1 ELLTTMGDR 9 0 J3QRS3;P19105;O14950;P24844;P24844-2 J3QRS3;P24844 MYL12A;MYL12B;MYL9 Myosin regulatory light chain 12A;Myosin regulatory light chain 12B;Myosin regulatory light polypeptide 9 0 0 114.28 0.0022243 5162200 1620.1 1951.6 1759.3 1992.8 2055.6 2187.1 1728.9 1595.2 1983.5 1643.2 FALSE FALSE TRUE 1491.867375 2120.287608 1824.501206 1984.554322 2031.088313 1733.470806 1777.408281 2081.569137 1765.915012 1700.301078 0.87741365 1.247007154 1.073045962 1.167178183 1.194546271 1.01950815 1.045349147 1.224235616 1.038589598 1 10.73157452 -7.271060104 24.99825717 0.942112 1.131239969 0.450465401 0.082123135 372.9647215 969100.7746 0.013856068 0.015949838 5.36E-08 7.271060104 0.189127969 ELLTTMGDRFTDEEVDELYR ddPTM_HeLa_Curcumin_4h_R1 3 ELLTTMGDRFTDEEVDELYR 20 1 J3QRS3;P19105;O14950 J3QRS3 MYL12A;MYL12B Myosin regulatory light chain 12A;Myosin regulatory light chain 12B 0 0 ;; ;; 90.872 0.0061083 80007100 5369.42 3706.52 3710.31 4000.88 2927.03 6373.7 4462.57 4386.6 6311.2 4694.44 FALSE FALSE TRUE 4944.424741 4026.895073 3847.817353 3984.325419 2892.127079 5051.722774 4587.777704 5724.054147 5618.87715 4857.571441 1.017879984 0.828993484 0.792127795 0.820229917 0.595385393 1.039968807 0.944459131 1.178377759 1.156725582 1 12.2460195 -7.272332464 23.73698454 1.008443333 0.87656915 0.187553825 0.153680548 524.8596 1143712.505 0.025189906 0.02896991 5.34E-08 7.272332464 -0.131874183 ELNSNHDGADETS(ph)EKEQQEAIEHIDEVQNEIDR ddPTM_HeLa_Curcumin_4h_R1 1 ELNSNHDGADETSEKEQQEAIEHIDEVQNEIDR 33 1 Q01105-2 Q01105-2 SET Protein SET 1 0 ELNSNHDGADET(0.208)S(0.792)EKEQQEAIEHIDEVQNEIDR 99.319 1.71E-11 11566000 543.67 597.37 577.32 383.21 1106.4 1131.4 590.96 345.21 725.51 409.92 TRUE FALSE FALSE 500.6379458 649.004001 598.7159871 381.6243786 1093.206903 896.7348865 607.5407471 450.4629398 645.9233681 424.1646895 1.180291425 1.530075504 1.411517747 0.899708033 2.577317089 2.114119607 1.43232278 1.062000093 1.522812681 1 8.728480715 -6.958726953 0.776000844 1.049667361 1.693452807 0.07607438 0.475650245 0.630192394 0.768402518 0.107656844 0.15544664 1.10E-07 6.958726953 0.643785446 ELNT(ph)LADQVDT(ph)T(ph)HELLT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 ELNTLADQVDTTHELLTK 18 0 A0A0G2JME4;Q9BWW9 A0A0G2JME4 APOL5 Apolipoprotein L5 4 0 ELNT(1)LADQVDT(1)T(1)HELLT(1)K 51.301 0.0086392 0 2713.5 3017.9 2850 2536.9 2318.3 3661.1 3241.8 2595.2 4081.1 4098.1 TRUE FALSE FALSE 2498.723612 3278.753828 2955.623507 2526.40298 2290.655787 2901.746591 3332.756183 3386.464533 3633.41354 4240.50867 0.589250915 0.773198237 0.696997398 0.595778284 0.540184201 0.684292102 0.785933114 0.798598658 0.856834362 1 12.05002162 -9.384961465 0.988011129 1.009714823 0.675038132 0.504080313 0.093339035 0.29440588 0.4897562 0.07269436 0.016613648 4.12E-10 9.384961465 -0.334676691 ELNVS(ph)FINEK ddPTM_HeLa_Curcumin_4h_R1 2 ELNVSFINEK 10 0 C9JEJ2;P49585;C9J050;Q9Y5K3-2;Q9Y5K3-4;Q9Y5K3-3;Q9Y5K3 C9JEJ2 PCYT1A;PCYT1B Choline-phosphate cytidylyltransferase A;Choline-phosphate cytidylyltransferase B 1 0 ELNVS(1)FINEK;ELNVS(1)FINEK ; 128.31 0.0031585 12179600 2056.47 1788.94 2062.04 2238.17 2415.8 3009.6 2452.36 1071.18 1983.86 2632.6 TRUE FALSE FALSE 1893.69823 1943.568002 2138.461016 2228.909046 2386.993163 2385.375035 2521.166621 1397.777851 1766.235521 2724.082654 0.695169152 0.713476149 0.785020606 0.818223721 0.876255777 0.875661769 0.925510325 0.513118737 0.648378095 1 11.41155476 -9.44402272 1.180845716 0.999791212 0.778164298 0 0.154893697 0.425619312 1.063134715 0.076390485 0.019118819 3.60E-10 9.44402272 -0.221626914 ELNYFAK ddPTM_HeLa_Curcumin_4h_R1 2 ELNYFAK 7 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 0 ; ; 126.67 0.0088512 30868000 12753.4 8912.6 10871.4 9763.5 11208.3 14997 11198.1 12231.9 11934.3 10814.2 FALSE FALSE TRUE 11743.95493 9682.96543 11274.30365 9723.101224 11074.64834 11886.45315 11512.28855 15961.35 10625.13715 11189.99265 1.049505152 0.865323664 1.0075345 0.868910421 0.989692191 1.062239585 1.028802155 1.42639504 0.94952137 1 13.44992147 -4.235870463 3.388870885 1.000746888 1.495042674 0.796697361 0.067007535 0.127106992 2.289797514 0.009460355 0.166595819 5.81E-05 4.235870463 0.494295786 ELPAAVAPAGPASLAR ddPTM_HeLa_Curcumin_4h_R1 1 ELPAAVAPAGPASLAR 16 0 M0R0U3;M0R261;O95336 M0R0U3 PGLS 6-phosphogluconolactonase 0 0 91.093 0.0084985 0 566.91 576.1 373.82 645.55 705.79 594.49 369.94 445.06 568.5 535.8 FALSE FALSE TRUE 522.0384753 625.8955169 387.674098 642.8788851 697.3739152 471.1860727 380.3195208 580.7567452 506.1369723 554.4190101 0.941595555 1.128921457 0.699243877 1.159554188 1.257846326 0.849873587 0.6859785 1.047505108 0.912914173 1 9.114832916 -5.05080466 24.99795578 0.995941802 0.842036395 0.14188131 0.166586695 461.3709316 227012.8652 0.02196543 0.056001878 8.90E-06 5.05080466 -0.153905408 DKAITPPLPES(ph)TVPFSNGVLK ddPTM_HeLa_Curcumin_4h_R1 2 DKAITPPLPESTVPFSNGVLK 21 1 I3NI36;Q92667-2;Q92667 I3NI36 AKAP1 "A-kinase anchor protein 1, mitochondrial" 1 0 DKAIT(0.398)PPLPES(0.468)T(0.134)VPFSNGVLK;DKAIT(0.004)PPLPES(0.824)T(0.172)VPFSNGVLK ; 113.54 9.06E-06 63360000 8282.9 6801.6 6668.1 8117.6 7235.9 7276.2 4860.6 2810.1 9690.2 7705.1 TRUE FALSE FALSE 7627.299725 7389.499997 6915.225652 8084.011522 7149.616618 5767.0341 4996.975354 3666.886554 8627.209304 7972.851651 0.956658929 0.926832747 0.867346585 1.013942298 0.896745221 0.723333928 0.626748819 0.459921583 1.082073226 1 12.96088011 -4.706420454 0.913493835 0.972382206 0.358052053 0.907839469 0.056039803 0.206112815 0.195072104 0.007364724 0.107349545 1.97E-05 4.706420454 -0.614330152 down ELPESGIQLGT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 ELPESGIQLGTPR 13 0 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 0 ELPESGIQLGT(1)PR;ELPESGIQLGT(1)PR ; 157.37 0.00097679 70932000 2532.09 2490.47 2462.2 2392.59 2140.26 3378.5 3240.6 1606.67 3070.32 2321.09 TRUE FALSE FALSE 2331.672405 2705.735129 2553.451298 2382.690097 2114.738797 2677.761016 3331.522514 2096.536287 2733.513578 2401.747705 0.970823205 1.126569258 1.063163834 0.992065108 0.880499976 1.114921859 1.387124263 0.872921116 1.138135189 1 11.22986889 -5.016927219 24.51330799 0.997017257 1.160272744 0.070058012 0.137623311 545.2068928 789550.3931 0.016463175 0.04318387 9.62E-06 5.016927219 0.163255487 ELPFGDK(ac)DTK ddPTM_HeLa_Curcumin_4h_R1 1 ELPFGDKDTK 10 1 O75534-2;O75534;O75534-3;O75534-4;E9PLT0 O75534-2 CSDE1 Cold shock domain-containing protein E1 0 1 ELPFGDK(1)DTK 104.43 0.0069132 1863300 634.46 682.88 486.02 623.22 1056 1137.1 912.45 960.05 1466.4 648.31 FALSE TRUE FALSE 584.2418215 741.9051043 504.0323287 620.6412808 1043.40789 901.2526422 938.0508913 1252.764825 1305.539589 670.8387242 0.870912487 1.10593661 0.751346502 0.925172114 1.555378144 1.343471403 1.398325495 1.867460509 1.946130331 1 9.389822161 -5.763154455 24.99521887 0.935022336 1.516836034 0.192941827 0.355280198 15.25374836 222310.8468 0.021904628 0.04125548 1.73E-06 5.763154455 0.581813698 ELPPDQAEYCIAR ddPTM_HeLa_Curcumin_4h_R1 2 ELPPDQAEYCIAR 13 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144;P12814-4;P12814-3;P12814;P12814-2;H9KV75;H0YJW3 O43707;P12814-4 ACTN4;ACTN1 Alpha-actinin-4;Alpha-actinin-1 0 0 ; ; 158.05 9.28E-05 5937200 1093.39 740.89 1012.16 897.28 843.1 849.69 756.14 928.55 837.94 700.12 FALSE FALSE TRUE 1006.847028 804.9292303 1049.67154 893.5672931 833.0465831 673.454716 777.3552534 1211.66062 746.0200784 724.4491179 1.389810551 1.111091463 1.44892376 1.233443828 1.14990351 0.929609409 1.07302947 1.672526877 1.029775674 1 9.500740555 -9.562270615 1.341209246 1.000215957 1.25264687 0.181494311 0.200444324 0.617354108 1.992873532 0.140268229 0.033135187 2.74E-10 9.562270615 0.252430913 VLTTS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 VLTTSPSR 8 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 0 VLT(0.077)T(0.077)S(0.846)PSR 98.582 0.015883 17624000 6539.3 5477.8 5918 5880 5324.9 5109.7 3578.5 1665.8 6401.1 5869.4 TRUE FALSE FALSE 6021.707505 5951.276623 6137.326286 5855.670118 5261.404045 4049.890622 3678.903079 2173.694752 5698.915345 6073.361213 0.991495038 0.979898349 1.010532071 0.964156406 0.866308435 0.666828545 0.605744159 0.357906384 0.938346188 1 12.56827946 -4.705184053 0.817373796 0.999662312 0.229306133 0.970915444 0.035782347 0.125029278 0.088925585 0.004719628 0.075452636 1.97E-05 4.705184053 -0.770356179 down LGS(ph)PVDNLEDMDRDDLTDDSVFTR ddPTM_HeLa_Curcumin_4h_R1 2 LGSPVDNLEDMDRDDLTDDSVFTR 24 1 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 0 LGS(0.766)PVDNLEDMDRDDLT(0.23)DDS(0.004)VFTR;LGS(0.736)PVDNLEDMDRDDLT(0.255)DDS(0.009)VFTR ; 79.016 0.00012 28665000 1784.54 1705.01 1680.54 1721.76 1839.02 1786.67 924.3 444.69 2013.75 1556.29 TRUE FALSE FALSE 1643.291776 1852.383467 1742.822291 1714.635813 1817.090888 1416.094502 950.2333704 580.2739339 1792.846663 1610.370962 1.020443 1.150283699 1.082248955 1.064745859 1.128367892 0.879359189 0.590071103 0.360335567 1.113312837 1 10.65317735 -4.692164883 2.008490474 1.037487908 0.363179992 0.941905195 0.059905828 0.0667632 0.477233502 0.009086892 0.060074775 2.03E-05 4.692164883 -0.674307915 down ELPPPSEEIKTGEDEDEEDNDALLKENES(ph)PDVR ddPTM_HeLa_Curcumin_4h_R1 1 ELPPPSEEIKTGEDEDEEDNDALLKENESPDVR 33 2 A0A087WWS1;Q96FV9 A0A087WWS1 THOC1 THO complex subunit 1 1 0 ELPPPS(0.001)EEIKT(0.003)GEDEDEEDNDALLKENES(0.996)PDVR 45.079 0.0060983 11608000 1371.9 1184.1 1362.8 1370.9 1562.8 1678 1277 1044.2 1157.2 1083.6 TRUE FALSE FALSE 1263.312667 1286.448328 1413.306567 1365.227579 1544.164631 1329.963885 1312.829183 1362.571773 1030.258055 1121.255019 1.126695217 1.147328935 1.260468442 1.217588823 1.377175222 1.186138623 1.170856906 1.215220222 0.918843651 1 10.13089873 -7.780584948 0.653462065 1.017101366 1.239777445 0.705552068 0.066327727 0.26658651 0.257094595 0.021996203 0.017766963 1.66E-08 7.780584948 0.222676078 ELPPS(ph)PEKK ddPTM_HeLa_Curcumin_4h_R1 1 ELPPSPEKK 9 1 E7EVA0;P27816;P27816-6;P27816-5;P27816-4;B5MEG9;H7C4C5;H0Y2V1;F8W9U4;P27816-3 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 ELPPS(1)PEKK 123.62 0.0083455 82525000 11019 9919.3 10712 10702 12928 12436 11644 11902 10039 8840.1 TRUE FALSE FALSE 10146.83452 10776.68009 11108.99614 10657.71796 12773.84204 9856.633417 11970.6993 15530.86501 8937.746816 9147.292817 1.109271861 1.178127814 1.214457257 1.16512264 1.396461478 1.077546506 1.308660337 1.697864638 0.97709202 1 13.15912912 -1 0.273883775 1.031263279 4.863662212 0.677231267 0.115252732 20.75973061 0.263831079 0.05061285 38.29000144 0.1 1 3.832398933 ELPQVSFVK ddPTM_HeLa_Curcumin_4h_R1 1 ELPQVSFVK 9 0 O76003 O76003 GLRX3 Glutaredoxin-3 0 0 98.044 0.0064616 0 467.31 365.19 513.62 467.48 409.62 760.95 779.88 539.63 448.32 443.69 FALSE FALSE TRUE 430.3219204 396.7553963 532.655209 465.5456916 404.735549 603.1203923 801.7613339 704.1607028 399.1404176 459.1081945 0.937299586 0.864187137 1.160195386 1.014021743 0.881568994 1.313678126 1.746345074 1.533757644 0.869382038 1 8.842690372 -5.013110714 3.524861236 0.97532913 1.634898451 0.884454531 0.098827828 0.046842552 1.233730951 0.012670068 0.039268331 9.70E-06 5.013110714 0.659569321 ELPSGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 ELPSGKK 7 1 P30041 P30041 PRDX6 Peroxiredoxin-6 0 1 ELPSGK(1)K 101.6 0.0067345 74515000 14686 12197 11497 11143 9823.6 12877 9748 10841 13095 10895 FALSE TRUE FALSE 13523.5876 13251.25433 11923.08893 11096.89322 9706.459986 10206.16505 10021.50264 14146.37099 11658.51126 11273.60044 1.199580176 1.175423451 1.057611452 0.984325574 0.860990243 0.905315485 0.888935411 1.254822811 1.03414267 1 13.46066072 -6.333301903 3.437071865 1.103193336 0.962239781 0.195102344 0.116234201 0.294728058 6.82846171 0.019524349 0.031083881 4.64E-07 6.333301903 -0.140953555 ELPSLSPAPDTGLS(ph)PSKR ddPTM_HeLa_Curcumin_4h_R1 3 ELPSLSPAPDTGLSPSKR 18 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;A0A0A0MSL0 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 0 ELPSLSPAPDT(0.002)GLS(0.964)PS(0.034)KR;ELPSLSPAPDT(0.014)GLS(0.981)PS(0.005)KR;ELPSLSPAPDT(0.001)GLS(0.989)PS(0.009)KR ;; 193.27 8.45E-09 132518000 6025.3 4320.25 4975.03 5328.72 5201.9 6441.9 4835.9 3605.65 5629.1 5263.3 TRUE FALSE FALSE 5548.391147 4693.673159 5159.408988 5306.671169 5139.87074 5105.777325 4971.582339 4704.996087 5011.601813 5446.199283 1.018763886 0.861825452 0.947341204 0.974380645 0.943753703 0.937493665 0.912853548 0.863904503 0.920201695 1 12.41103406 -1 0.168263448 1.026987125 0.420939689 0.007328124 0.048863602 37.65494679 0.393063466 0.0667228 5.759312587 0.1 1 -0.606047436 ELPSLSPAPDTGLSPS(ph)KR ddPTM_HeLa_Curcumin_4h_R1 1 ELPSLSPAPDTGLSPSKR 18 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;A0A0A0MSL0 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 0 ELPSLSPAPDT(0.01)GLS(0.328)PS(0.661)KR 95.591 0.00095328 24863000 2461 2146.2 2381.9 2523.9 2704.6 3207.8 2254.5 1733.2 2727.2 2642.5 TRUE FALSE FALSE 2266.209253 2331.707965 2470.175309 2513.456771 2672.349411 2542.466121 2317.755202 2261.644701 2428.032983 2734.326678 0.828799745 0.852753983 0.903394364 0.919223292 0.977333628 0.929832613 0.847651168 0.827130393 0.88798204 1 11.4169699 -9.506295175 1.269097588 0.999701998 0.882772417 0.009467557 0.056895977 0.363319155 1.051612227 0.036400313 0.008897616 3.12E-10 9.506295175 -0.116929581 ELPSQASGGLANPPPVNLEDS(ph)LDEDLIRNPASSVEAVSK ddPTM_HeLa_Curcumin_4h_R1 2 ELPSQASGGLANPPPVNLEDSLDEDLIRNPASSVEAVSK 39 1 Q9NPG3;Q9NPG3-2;K7EJT1 Q9NPG3 UBN1 Ubinuclein-1 1 0 ELPSQASGGLANPPPVNLEDS(0.974)LDEDLIRNPAS(0.011)S(0.015)VEAVSK;ELPSQASGGLANPPPVNLEDS(0.918)LDEDLIRNPAS(0.04)S(0.04)VEAVS(0.002)K ; 112.73 2.06E-19 6987500 1964.69 1543.29 1612.21 1831.29 1943.91 2112.08 1551.96 1203.31 2514.91 1831.49 TRUE FALSE FALSE 1809.182713 1676.685111 1671.959921 1823.712607 1920.730143 1674.0108 1595.503821 1570.19368 2239.030665 1895.134141 0.954646256 0.884731626 0.882238299 0.962313204 1.013506169 0.88332048 0.841894928 0.828539598 1.181462893 1 10.88808425 -1 0.188705352 0.999076983 0.263853852 0.414210936 0.076370153 35.10783376 0.391096486 0.055683616 7.55292863 0.1 1 -0.735223131 ELQEAAAVPT(ph)TPRR ddPTM_HeLa_Curcumin_4h_R1 1 ELQEAAAVPTTPRR 14 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 0 ELQEAAAVPT(0.563)T(0.437)PRR 106.31 0.0018495 11975000 2676.1 1869.9 1995.9 2094 1701.6 2901.2 2820.2 932.09 2810.7 1978.8 TRUE FALSE FALSE 2464.283861 2031.525824 2069.86981 2085.335583 1681.309531 2299.458417 2899.327222 1216.27995 2502.373242 2047.563153 1.20352032 0.992167602 1.010894246 1.018447504 0.82112707 1.123021976 1.415989157 0.5940134 1.222122619 1 10.99969223 ELQEAAAVPTT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 ELQEAAAVPTTPR 13 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 0 ELQEAAAVPT(0.005)T(0.995)PR;ELQEAAAVPT(0.006)T(0.994)PR ; 159.18 0.000848 20808000 8252.5 6891.9 6610.9 8143.1 7465.4 11308.7 9245.3 3127.7 7695.7 6045.7 TRUE FALSE FALSE 7599.305917 7487.605126 6855.90577 8109.40601 7376.379981 8963.148145 9504.698236 4081.321332 6851.500964 6255.787625 1.214764051 1.196908459 1.09593007 1.296304558 1.1791289 1.432776923 1.519344774 0.652407271 1.095225953 1 12.61097582 -9.30732931 0.500572898 0.948165208 1.225913459 0.054460348 0.221249438 2.711625187 0.900952681 0.374637148 0.055048684 4.93E-10 9.30732931 0.277748251 ELQEAAAVPTT(ph)PRR ddPTM_HeLa_Curcumin_4h_R1 1 ELQEAAAVPTTPRR 14 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 0 ELQEAAAVPT(0.251)T(0.749)PRR 101.54 0.0024241 11469000 4394.1 3129.3 3664.9 3610.6 3741.5 5631.8 5216.3 1791.2 4438.6 3791.2 TRUE FALSE FALSE 4046.302348 3399.782748 3800.724418 3595.660294 3696.885056 4463.701197 5362.655339 2337.328634 3951.696685 3922.943918 1.031445372 0.866640671 0.968844954 0.916571934 0.942375199 1.137844764 1.366997707 0.595809852 1.007329385 1 11.937721 -4.217711813 23.77460936 1.01660199 0.595807048 0.482126108 0.133545377 12447.8906 6767615.406 0.018003104 11.43085274 6.06E-05 4.217711813 -0.420794943 ELQELVQYPVEHPDK ddPTM_HeLa_Curcumin_4h_R1 2 ELQELVQYPVEHPDK 15 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 ; ; 158.65 0.00026521 34607000 7612.6 6512.8 7436.4 7239.5 8374 9572.1 7376.1 7215.6 7037.4 7662.6 FALSE FALSE TRUE 7010.054677 7075.737412 7711.999526 7209.544867 8274.145519 7586.73856 7583.053514 9415.603223 6265.414827 7928.87478 0.884117214 0.892401205 0.972647411 0.909277176 1.043545995 0.956849335 0.956384572 1.187508125 0.790202267 1 12.95290043 -4.260461008 5.299404613 0.947693001 1.197520618 0.550031565 0.067830039 0.078145651 7.705257496 0.007603543 0.070708722 5.49E-05 4.260461008 0.249827617 ELQELVQYPVEHPDKFLK ddPTM_HeLa_Curcumin_4h_R1 1 ELQELVQYPVEHPDKFLK 18 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 62.94 0.010838 9555900 2617.7 1843.6 2263.2 2004.7 1689.2 2965.4 2403.1 2352.6 3035.5 2645 FALSE FALSE TRUE 2410.506283 2002.952569 2347.076183 1996.405083 1669.057393 2350.342613 2470.524518 3069.89691 2702.513244 2736.913553 0.880738919 0.731828949 0.857563141 0.729436661 0.609831973 0.858756613 0.902668086 1.12166382 0.987430985 1 11.41833415 -8.275838556 0.97144063 0.981441413 0.824760817 0.190196961 0.127893637 0.575587564 1.136240943 0.042465607 0.028163077 5.30E-09 8.275838556 -0.156680597 ELQGDGPPSS(ph)PTNDPTVK ddPTM_HeLa_Curcumin_4h_R1 1 ELQGDGPPSSPTNDPTVK 18 0 Q12873-2;Q12873;Q12873-3;A0A5F9ZHX5 Q12873-2 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 0 ELQGDGPPS(0.228)S(0.76)PT(0.012)NDPTVK 208.4 2.12E-12 31497000 4608.9 4033.9 4788.9 4823.6 4484.2 6120.8 4399 3860.4 5105.7 4497.4 TRUE FALSE FALSE 4244.100702 4382.572341 4966.380847 4803.641221 4430.728844 4851.277084 4522.424101 5037.418189 4545.617484 4653.684315 0.911987237 0.941742509 1.067193327 1.032223266 0.952090547 1.042459427 0.971794345 1.08245808 0.97677822 1 12.18415763 -6.781036164 24.99978743 0.956024939 1.020146579 0.369220471 0.042681625 226.8823252 289435.0901 0.007685813 0.010108659 1.66E-07 6.781036164 0.064121639 ELQGDGPPSS(ph)PTNDPTVKYETQPR ddPTM_HeLa_Curcumin_4h_R1 1 ELQGDGPPSSPTNDPTVKYETQPR 24 1 Q12873-2;Q12873;Q12873-3;A0A5F9ZHX5 Q12873-2 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 0 ELQGDGPPS(0.182)S(0.817)PTNDPTVKYETQPR 146.63 5.49E-07 24331000 7296.8 4808.3 4409.1 5936.1 3731.1 6551.9 4182 4311.4 8838.2 7359.9 TRUE FALSE FALSE 6719.25058 5223.908027 4572.505125 5911.537991 3686.609069 5192.962085 4299.335665 5625.926013 7868.671572 7615.655977 0.882294395 0.685943278 0.600408571 0.776234905 0.484082931 0.681879814 0.564539112 0.738731638 1.033223086 1 12.89475259 -7.373229534 1.273392055 0.963686371 0.631364174 0.755785083 0.085163311 0.132985137 0.419883491 0.01600155 0.018097672 4.23E-08 7.373229534 -0.332322198 ELRAAIDSTYR ddPTM_HeLa_Curcumin_4h_R1 1 ELRAAIDSTYR 11 1 Q8NF91;Q8NF91-4;A0A0C4DG40;E7ENN3;A0A5F9ZHI3;Q8NF91-5;Q8NF91-6;F5GXQ8;A0A5F9ZHR3;Q8NF91-10;A0A5F9ZI52;Q8NF91-7 Q8NF91 SYNE1 Nesprin-1 0 0 109.79 0.0058566 16600000 2170.1 3152.9 2155 3390.8 2164.6 3092.3 1739.7 583.12 3213.2 2718.7 FALSE FALSE TRUE 1998.334295 3425.422627 2234.866196 3376.769768 2138.788559 2450.922123 1788.5113 760.9106036 2860.719999 2813.174623 0.710348472 1.217635976 0.794428536 1.20034133 0.76027579 0.871229999 0.635762631 0.270481113 1.016900969 1 11.45798339 -4.282752353 1.483022766 0.90217545 0.031392859 0.612751613 0.167098296 0.623849652 1.268330313 0.024959968 0.786684439 5.21E-05 4.282752353 -0.870782591 ELRAPS(ph)PPVEHPR ddPTM_HeLa_Curcumin_4h_R1 1 ELRAPSPPVEHPR 13 1 Q86WR7;Q86WR7-2 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 0 ELRAPS(1)PPVEHPR 115.26 0.0011128 6312100 875.34 630.46 603.07 655.03 594.23 779.96 632.3 636.82 974.53 817.5 TRUE FALSE FALSE 806.0559153 684.9541531 625.4203047 652.3196594 587.1441954 618.187504 650.0406363 830.9834864 867.6264972 845.9080642 0.952888321 0.809726473 0.739347845 0.771147229 0.6940993 0.730797507 0.768453055 0.982356738 1.025674697 1 9.724357065 -7.258666134 2.677560496 0.980717961 0.773139502 0.621077975 0.074544211 0.131209299 1.819724768 0.012894644 0.015292371 5.51E-08 7.258666134 -0.207578459 ELS(ph)APAR ddPTM_HeLa_Curcumin_4h_R1 1 ELSAPAR 7 0 F5H672;F5H5N2;B4DNC9;B3KQ30;Q9H1K1 F5H672 ISCU "Iron-sulfur cluster assembly enzyme ISCU, mitochondrial" 1 0 ELS(1)APAR 83.647 0.0185 4497900 10730 9262.7 9335.5 9411.5 9419.4 12918 10415 7797.3 11563 9848.4 TRUE FALSE FALSE 9880.709178 10063.32651 9681.481842 9372.557707 9307.079807 10238.66118 10707.21687 10174.66088 10294.56783 10190.63117 0.969587557 0.987507677 0.950037508 0.919722984 0.91329768 1.004713154 1.050692219 0.998432846 1.010199237 1 13.31495579 -5.007552968 24.79062772 0.972954677 1.025347582 0.352183658 0.032597937 305.9285518 1004142.759 0.004911993 0.013891589 9.83E-06 5.007552968 0.052392905 ELS(ph)DLEEENR ddPTM_HeLa_Curcumin_4h_R1 2 ELSDLEEENR 10 0 Q5M775-4;Q5M775;Q5M775-5;Q5M775-3;Q5M775-2 Q5M775-4 SPECC1 Cytospin-B 1 0 ELS(1)DLEEENR;ELS(1)DLEEENR ; 107.09 0.0088587 32643000 3450.3 3003.7 2915.9 2983.4 3012.5 3175.7 2645.2 1922.22 3165.1 2793.8 TRUE FALSE FALSE 3177.205114 3263.326444 3023.965819 2971.055481 2976.577905 2517.024022 2719.417193 2508.296029 2817.896449 2890.884342 1.099042624 1.128833276 1.046034867 1.027732393 1.029642681 0.870676141 0.940686956 0.867656998 0.974752399 1 11.49729518 -5.345549054 4.432011611 1.05256666 0.897763936 0.69094504 0.046026912 0.098806622 3.495915829 0.007087631 0.016537545 4.51E-06 5.345549054 -0.154802724 ELS(ph)DLEEENRVLK ddPTM_HeLa_Curcumin_4h_R1 1 ELSDLEEENRVLK 13 1 Q5M775-4;Q5M775;Q5M775-5;Q5M775-3;Q5M775-2 Q5M775-4 SPECC1 Cytospin-B 1 0 ELS(1)DLEEENRVLK 77.42 0.0089562 0 1440.4 915.23 830.47 1079.1 976.45 1243.3 862.75 551.38 1193.3 1001.5 TRUE FALSE FALSE 1326.39082 994.338403 861.2479488 1074.63497 964.8064715 985.4255651 886.956443 719.4932238 1062.397975 1036.30205 1.279926851 0.959506355 0.831078109 1.036990103 0.931008938 0.950905737 0.855886025 0.694289106 1.025181775 1 10.01722885 -7.058452994 7.298298226 1.131946773 0.894296331 0.431300536 0.110058241 0.194123389 21.29319382 0.021832657 0.026876498 8.74E-08 7.058452994 -0.237650442 S(ph)VSVVTGSEQK ddPTM_HeLa_Curcumin_4h_R1 2 SVSVVTGSEQK 11 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 0 S(0.965)VS(0.035)VVTGSEQK;S(0.674)VS(0.276)VVT(0.05)GSEQK ; 210.44 7.97E-08 80009000 4989.4 3388 5296.2 5656.8 4488.8 5217.7 7201.2 12922.4 3881.1 4446.6 TRUE FALSE FALSE 4594.483725 3680.843623 5492.481831 5633.39366 4435.273992 4135.490204 7403.246291 16862.38027 3455.35304 4601.119019 0.998557896 0.799988787 1.193727397 1.224352954 0.963955502 0.898800963 1.609009952 3.664843314 0.750981017 1 12.16776906 -4.267656984 2.513700548 1.007488285 4.22583111 0.967718749 0.147176779 0.049907197 0.395377303 0.017113878 0.339630511 5.40E-05 4.267656984 3.218342825 up ELS(ph)PAALEK ddPTM_HeLa_Curcumin_4h_R1 2 ELSPAALEK 9 0 O75683 O75683 SURF6 Surfeit locus protein 6 1 0 ELS(1)PAALEK;ELS(1)PAALEK ; 116.84 0.0070544 457400000 15096.9 14363.9 14087.6 14650.1 14880.8 17218.6 14505.5 9199 15433.3 13418.3 TRUE FALSE FALSE 13901.96443 15605.45151 14609.69885 14589.48177 14703.35618 13647.26827 14912.48529 12003.73275 13740.3056 13884.58493 1.001251713 1.123940802 1.052224386 1.050768305 1.058969804 0.982907904 1.074031768 0.864536665 0.989608669 1 13.76119643 -4.249204952 24.37491517 1.021997848 0.864536527 0.556778191 0.044384227 869.8951122 1733066.95 0.006470537 0.142702694 5.63E-05 4.249204952 -0.157461322 ELS(ph)PAGSISK ddPTM_HeLa_Curcumin_4h_R1 1 ELSPAGSISK 10 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 0 ELS(1)PAGSISK 174.57 0.00041194 446760000 5663.4 4577.1 5740.4 4993.5 5042.7 4564.6 3475.7 3046 4879.2 4201.4 TRUE FALSE FALSE 5215.135914 4972.724129 5953.144274 4972.83822 4982.569096 3617.850506 3573.218788 3974.711378 4343.963967 4347.398337 1.19959928 1.143839083 1.369357904 1.143865327 1.146103649 0.832187489 0.821921184 0.914273565 0.999210017 1 12.08593658 -5.261753152 24.9288044 1.128064373 0.852706777 0.626121443 0.101156778 15.69243372 1246815.164 0.016497873 0.039205651 5.47E-06 5.261753152 -0.275357595 ELS(ph)PPPGLPSK ddPTM_HeLa_Curcumin_4h_R1 1 ELSPPPGLPSK 11 0 A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YHT2;Q7Z4S6-3;H0YI78;H0YIM6 A0A1B0GV47 KIF21A Kinesin-like protein KIF21A 1 0 ELS(1)PPPGLPSK 104.59 0.0087078 6302500 3127.2 2774.7 3082.9 2818 3449.7 3440.9 2407.8 2543.8 3389.8 2593.1 TRUE FALSE FALSE 2879.67882 3014.532704 3197.154986 2806.339863 3408.564581 2727.218553 2475.356388 3319.39291 3017.947421 2683.210032 1.073221547 1.123479962 1.191541082 1.045889002 1.270330887 1.016401445 0.922535455 1.237097682 1.124752585 1 11.38974427 -8.25848641 0.91900279 1.010846012 1.108355729 0 0.105219461 0.703712336 1.252783075 0.031825407 0.020815823 5.51E-09 8.25848641 0.097509717 DLGSTEDGDGTDDFLT(ph)DKEDEK ddPTM_HeLa_Curcumin_4h_R1 2 DLGSTEDGDGTDDFLTDKEDEK 22 1 Q15527 Q15527 SURF2 Surfeit locus protein 2 1 0 DLGSTEDGDGT(0.001)DDFLT(0.999)DKEDEK;DLGSTEDGDGTDDFLT(1)DKEDEK ; 136.77 7.95E-06 178055000 11506.2 9813.2 12026.6 12088.8 12437.9 12039.6 11647.7 15766.3 10532.1 9330.2 TRUE FALSE FALSE 10595.47213 10661.40928 12472.31638 12038.77975 12289.58617 9542.451246 11974.50311 20573.37229 9376.75498 9654.423756 1.097473282 1.104303017 1.291875796 1.246970306 1.2729487 0.988401948 1.240312567 2.130978794 0.971239218 1 13.23697444 -4.267515253 3.457247822 1.096149211 2.25310399 0.874016119 0.113870714 0.075785274 1.548665511 0.017283358 0.22724053 5.40E-05 4.267515253 1.156954779 up ELSDIAHR ddPTM_HeLa_Curcumin_4h_R1 6 ELSDIAHR 8 0 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 ;;;;; ;;;;; 141.52 0.00016851 309282000 80357.3 68692.7 66722.3 66840.8 79420 102636.5 72746 67373.9 92150.7 71069 FALSE FALSE TRUE 73996.93491 74630.1909 69195.08713 66564.23048 78472.96837 81348.53295 74787.05697 87915.89196 82041.99876 73538.64246 1.006231995 1.014843195 0.940935062 0.905159903 1.067098409 1.106201178 1.016976306 1.19550605 1.11563113 1 16.16621492 -1.00000006 0.675776302 0.996349182 20.87024578 0.403895051 0.063112086 134.2588839 0.729962515 0.008554884 4020.605237 0.099999986 1.00000006 19.8738966 ELSDQATAS(ph)PIVAR ddPTM_HeLa_Curcumin_4h_R1 2 ELSDQATASPIVAR 14 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 ELSDQATAS(1)PIVAR;ELSDQATAS(1)PIVAR ; 223.14 1.74E-14 348100000 4380.6 3999.9 4228.2 4374 4301.3 5472 4790.9 2917.2 4212 3373.2 TRUE FALSE FALSE 4033.870888 4345.633533 4384.900812 4355.901547 4250.009807 4337.045518 4925.31976 3806.640851 3749.954138 3490.418449 1.155698363 1.245017924 1.256267945 1.247959696 1.217621861 1.24255747 1.411097217 1.090597276 1.074356612 1 11.76918429 -8.174845023 0.547191966 1.000749357 1.261279889 0.518710968 0.077111906 0.354736943 0.240607176 0.039703841 0.021269674 6.69E-09 8.174845023 0.260530532 ELSEPMEFQYLPDTDDR ddPTM_HeLa_Curcumin_4h_R1 1 ELSEPMEFQYLPDTDDR 17 0 Q2TAM5;E9PKH5;A0A087X0W8;Q04206-2;Q04206-3;Q04206-4;Q04206 Q2TAM5 RELA Transcription factor p65 0 0 149.82 0.001922 4859800 1129.9 1274.4 1376.3 1307.3 1401.6 1666.6 1194.6 1005.4 1196.5 1245.2 FALSE FALSE TRUE 1040.467223 1384.553457 1427.306889 1301.890739 1384.886835 1320.928374 1228.117261 1311.941832 1065.246943 1288.470607 0.807521116 1.074571239 1.107752773 1.010415551 1.074829979 1.025190925 0.953158927 1.018216344 0.826753003 1 10.33144391 -7.242281777 24.95298234 0.90910719 1.037067517 0.549912999 0.064373748 661.5583583 861687.5008 0.013545716 0.016576593 5.72E-08 7.242281777 0.127960327 ELSEQIQR ddPTM_HeLa_Curcumin_4h_R1 1 ELSEQIQR 8 0 E7EQR4;P15311 E7EQR4 EZR Ezrin 0 0 93.143 0.019688 7681000 2489 1808.7 1825.4 2254.1 2203.8 2478.7 2002.7 1903.4 2290.3 1982.1 FALSE FALSE TRUE 2291.993024 1965.035969 1893.05093 2244.773131 2177.521124 1964.589679 2058.890372 2483.737898 2039.05982 2050.977827 1.117512336 0.958097129 0.922999217 1.094489224 1.061699008 0.957879531 1.003857938 1.211001828 0.99418911 1 11.00209618 -2.911871429 9.954226496 1.042877795 1.041957242 0 0.084480155 0 0 0.011166946 0 0.001224979 2.911871429 -0.000920553 ELSESVQQQSTPVPLIS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 ELSESVQQQSTPVPLISPK 19 0 Q9ULU4-9;Q9ULU4-11;Q9ULU4-23;Q9ULU4-21;Q9ULU4;Q9ULU4-5;H7C4X9;A0A087WYS3;A0A087WVZ6;Q9ULU4-10;Q9ULU4-13;Q9ULU4-20;Q9ULU4-12;Q9ULU4-7;Q9ULU4-19;Q9ULU4-16;Q9ULU4-22;Q9ULU4-18;Q9ULU4-14;Q9ULU4-15;Q9ULU4-6;Q9ULU4-3;Q9ULU4-4;A0A087WV57;Q9ULU4-8;Q9ULU4-17;Q9ULU4-2 Q9ULU4-9 ZMYND8 Protein kinase C-binding protein 1 1 0 ELSESVQQQST(0.014)PVPLIS(0.985)PK;ELSESVQQQS(0.001)T(0.006)PVPLIS(0.994)PK ; 114.21 0.00015971 17896300 7964.7 6392.5 6600.7 7461.4 6976 8816.9 6562.7 5430.4 7803.7 7159.8 TRUE FALSE FALSE 7334.285591 6945.039216 6845.327749 7430.526704 6892.815756 6988.175553 6746.831699 7086.103962 6947.653634 7408.602517 0.989968833 0.937429049 0.923970173 1.002959288 0.93038002 0.943251516 0.910675351 0.956469718 0.937781939 1 12.85498572 -7.307680977 5.301169602 0.995511335 0.943307605 0.10748704 0.029571193 0.116252781 7.89171042 0.003889043 0.004471294 4.92E-08 7.307680977 -0.05220373 ELSESVQQQSTPVPLIS(ph)PKR ddPTM_HeLa_Curcumin_4h_R1 2 ELSESVQQQSTPVPLISPKR 20 1 Q9ULU4-9;Q9ULU4-11;Q9ULU4-23;Q9ULU4-21;Q9ULU4;Q9ULU4-5;H7C4X9;A0A087WYS3;A0A087WVZ6;Q9ULU4-10;Q9ULU4-13;Q9ULU4-20;Q9ULU4-12;Q9ULU4-7;Q9ULU4-19;Q9ULU4-16;Q9ULU4-22;Q9ULU4-18;Q9ULU4-14;Q9ULU4-15;Q9ULU4-6;Q9ULU4-3;Q9ULU4-4;A0A087WV57;Q9ULU4-8;Q9ULU4-17;Q9ULU4-2 Q9ULU4-9 ZMYND8 Protein kinase C-binding protein 1 1 0 ELSESVQQQST(0.001)PVPLIS(0.999)PKR;ELSESVQQQSTPVPLIS(1)PKR ; 162.98 2.88E-06 53254000 4697.9 3223.9 3449.6 3654.6 3343.4 4827.6 3641.4 2712.56 4727.3 4137.9 TRUE FALSE FALSE 4326.056258 3502.559551 3577.445211 3639.478234 3303.532139 3826.301342 3743.567884 3539.607057 4208.727017 4281.691717 1.010361451 0.818031699 0.835521436 0.850009406 0.77154834 0.893642419 0.874319809 0.826684239 0.982958909 1 12.06396521 -7.264881039 24.96687411 1.004892911 0.839781285 0.84079224 0.031704814 70.77760177 513442.0355 0.005151492 0.006018292 5.43E-08 7.264881039 -0.165111626 ELSKEDLSPAFDHS(ph)PNK ddPTM_HeLa_Curcumin_4h_R1 1 ELSKEDLSPAFDHSPNK 17 1 K7EIY0;K7ENP9;K7EIE9;D3DUJ3;K7EQG9;P17706-3;P17706-2;P17706-4;P17706 K7EIY0 PTPN2 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 2 1 0 ELSKEDLSPAFDHS(1)PNK 154.55 7.99E-05 31933000 1742.7 1707.8 1815.3 1927.3 2177.7 2090.6 1743.7 874.76 1864.9 1525.3 TRUE FALSE FALSE 1604.763456 1855.414622 1882.576615 1919.325343 2151.73235 1656.985994 1792.623529 1141.470297 1660.325136 1578.304061 1.016764447 1.175574889 1.192784496 1.216068177 1.363319276 1.049852202 1.135790988 0.72322585 1.051967854 1 10.62415945 -7.302575846 8.824351015 1.007820943 1.13565604 0.072100663 0.155789317 0.615752414 126.7600036 0.026016261 0.029785948 4.98E-08 7.302575846 0.127835098 ELSLT(ph)PITGAKPSATGYLGSVAAK ddPTM_HeLa_Curcumin_4h_R1 2 ELSLTPITGAKPSATGYLGSVAAK 24 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 0 ELS(0.126)LT(0.437)PIT(0.437)GAKPS(0.001)ATGYLGSVAAK;ELS(0.084)LT(0.845)PIT(0.071)GAKPSATGYLGSVAAK ; 76.614 0.00036329 36788000 3751.6 3151.4 2875.1 3359.6 3180.9 5839.8 4761.1 2503.81 3957 2531.9 TRUE FALSE FALSE 3454.656901 3423.792974 2981.653735 3345.698865 3142.969845 4628.559652 4894.683652 3267.210143 3522.927 2619.883337 1.318630052 1.306849403 1.138086454 1.277041164 1.19966023 1.766704489 1.868283058 1.247082302 1.344688502 1 11.35528685 -1 0.082119819 0.678037423 3.212491245 0.207630577 0.227110727 121.6899675 0.732973572 3.397058952 35.10673074 0.1 1 2.534453823 ELSNS(ph)PLR ddPTM_HeLa_Curcumin_4h_R1 3 ELSNSPLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 ELSNS(1)PLR;ELSNS(1)PLR;ELS(0.013)NS(0.987)PLR ;; 147.3 0.0022393 1502089000 17447.7 18011.7 18979.7 16837.8 20905 20544.9 18147.8 13662.9 14337.8 12719 TRUE FALSE FALSE 16066.69613 19568.55109 19683.10438 16768.12965 20655.72153 16283.65615 18656.97843 17828.65531 12764.97921 13160.9843 1.220782258 1.486860757 1.495564764 1.27407869 1.569466314 1.237267348 1.417597498 1.35465972 0.969910678 1 13.68397977 -7.938414616 0.967288561 1.043885999 1.402941773 0.692826152 0.106948898 0.19007461 0.37860316 0.028411163 0.023195581 1.15E-08 7.938414616 0.359055774 ELSNS(ph)PLRENSFGS(ph)PLEFR ddPTM_HeLa_Curcumin_4h_R1 1 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 ELS(0.072)NS(0.921)PLRENS(0.025)FGS(0.983)PLEFR 85.11 0.0023489 87182000 4766 3619 3798.6 4222.2 4293.2 4806.1 4000.9 4340.7 4756.5 3397.3 TRUE FALSE FALSE 4388.766071 3931.810234 3939.379458 4204.729655 4242.006394 3809.260684 4113.154486 5664.159448 4234.72385 3515.355922 1.248455681 1.118467183 1.120620371 1.196103538 1.206707511 1.083605976 1.170053496 1.61126201 1.204635873 1 11.77945505 -1.000000002 0.024116034 3.97E-12 2.817169448 0.217149914 0.136727239 1821.52297 3.414032378 139.7047742 282.8606735 0.1 1.000000002 2.817169448 ELSNS(ph)PLRENSFGSPLEFR ddPTM_HeLa_Curcumin_4h_R1 1 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 ELS(0.117)NS(0.847)PLRENS(0.036)FGS(0.001)PLEFR 118.76 0.0024179 19006000 562.34 368.54 476.51 345.98 475.63 548.06 492.53 268.94 426.98 217.24 TRUE FALSE FALSE 517.8301956 400.3949554 494.1698798 344.5484264 469.9584229 434.3861781 506.3490662 350.938568 380.1413623 224.7890738 2.30362707 1.781202923 2.198371439 1.532763228 2.090663994 1.932416779 2.252551948 1.561190506 1.691102489 1 7.812428103 -9.416037058 1.081841943 0.986266836 1.987585908 0.272485496 0.329019384 0.236017881 0.483164058 0.183101933 0.043774504 3.84E-10 9.416037058 1.001319073 ELSNSPLRENS(ph)FGS(ph)PLEFR ddPTM_HeLa_Curcumin_4h_R1 1 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 ELS(0.001)NS(0.097)PLRENS(0.907)FGS(0.994)PLEFR 171.52 1.72E-05 61105000 4744.8 3582.7 4862.7 4588.4 4404.6 4938.5 4443.9 4705.6 5557.9 3697.8 TRUE FALSE FALSE 4369.244073 3892.372624 5042.91594 4569.414417 4352.078022 3914.199432 4568.583874 6140.315778 4948.212275 3826.298275 1.141898451 1.017268478 1.317962056 1.194212811 1.137412117 1.022972897 1.193995749 1.604766627 1.293211329 1 11.90173363 -4.282516842 3.117516643 1.094515845 1.670317234 0.5835304 0.111394255 0.143039111 2.153154346 0.014336729 0.195765791 5.22E-05 4.282516842 0.575801388 ELSNSPLRENSFGS(ph)PLEFR ddPTM_HeLa_Curcumin_4h_R1 3 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 ELS(0.002)NS(0.029)PLRENS(0.294)FGS(0.675)PLEFR;ELSNS(0.157)PLRENS(0.06)FGS(0.784)PLEFR;ELSNS(0.284)PLRENS(0.187)FGS(0.528)PLEFR ;; 160.38 0.00018908 1084486000 6868.4 6100.8 5350.5 6157 6080.3 7792.1 6997.4 4765 6303.7 5912.1 TRUE FALSE FALSE 6324.758892 6628.125967 5548.794237 6131.523965 6007.796394 6175.930625 7193.728211 6217.826565 5612.199881 6117.545035 1.033872061 1.083461737 0.907029569 1.002285056 0.982060019 1.009543958 1.175917491 1.016392446 0.917394126 1 12.5787371 -4.819539264 23.84035495 1.009601177 1.096154933 0.277751334 0.062206014 38.81878123 15928.40885 0.007133861 0.021401624 1.52E-05 4.819539264 0.086553756 ELSNSPLRENSFGSPLEFR ddPTM_HeLa_Curcumin_4h_R1 1 ELSNSPLRENSFGSPLEFR 19 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 0 85.046 0.0027937 5852800 602.25 605.41 674.82 930.33 625.87 720.95 687.64 508.88 859.71 652.19 FALSE FALSE TRUE 554.581277 657.7389427 699.8294228 926.480541 618.406909 571.4168432 706.9333277 664.0351694 765.4019639 674.853554 0.821780183 0.974639518 1.037009317 1.372861616 0.916357194 0.846727175 1.047535904 0.983969286 1.134174903 1 9.398430655 -6.970637656 4.922615766 0.914935964 1.034990033 0 0.151841161 0.309110581 18.98502365 0.024026853 0.031350354 1.07E-07 6.970637656 0.120054069 ELSSPIS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 ELSSPISPK 9 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 ELS(0.001)S(0.002)PIS(0.997)PK;ELS(0.108)S(0.207)PIS(0.685)PK;ELS(0.001)S(0.005)PIS(0.994)PK ;; 128.03 0.0042276 62074800 12705.5 11493.5 11986 12127.9 13060.4 13265.3 11682.6 5295.9 12437.6 11033.6 TRUE FALSE FALSE 11699.84627 12486.94693 12430.2117 12077.71796 12904.66326 10513.92725 12010.38231 6910.595531 11073.2264 11417.01678 1.024772626 1.093713635 1.088744279 1.057869862 1.130300805 0.920899693 1.05197203 0.605289075 0.969887897 1 13.47889811 -4.259592154 24.97261645 1.029465611 0.60528893 0.825814988 0.059455159 47.25192701 638745.3535 0.007876848 0.068462849 5.50E-05 4.259592154 -0.424176681 S(ph)QGGEEEGPLSDK ddPTM_HeLa_Curcumin_4h_R1 2 SQGGEEEGPLSDK 13 0 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 0 S(1)QGGEEEGPLSDK;S(1)QGGEEEGPLSDK ; 214.28 2.01E-13 172433000 3803.1 3963.2 3839.8 2950.8 3655.8 3311.4 2285.4 1204.63 4613.3 3248.4 TRUE FALSE FALSE 3502.080622 4305.761348 3982.106366 2938.590371 3612.206973 2624.578313 2349.522173 1571.916142 4107.232532 3361.281658 1.041888475 1.280987964 1.184698806 0.87424699 1.074651678 0.780826655 0.698995922 0.4676538 1.221924536 1 11.71479572 -4.691803537 1.09238837 1.049901194 0.397435353 0.754763912 0.120642675 0.350023213 0.52260229 0.017304402 0.219943484 2.03E-05 4.691803537 -0.652465841 down ELT(ph)DEEAER ddPTM_HeLa_Curcumin_4h_R1 2 ELTDEEAER 9 0 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 1 0 ELT(1)DEEAER;ELT(1)DEEAER ; 154.15 0.0039073 40299000 3716 3068.9 3512.8 3613.2 4390.4 3819.8 3200.2 2975.9 2858.3 3111.3 TRUE FALSE FALSE 3421.874679 3334.162041 3642.987458 3598.249536 4338.047347 3027.530422 3289.988999 3883.238211 2544.751641 3219.417443 1.062886295 1.035641416 1.131567286 1.117671007 1.347463454 0.940396974 1.021920598 1.206192822 0.790438545 1 11.65258394 -7.454252477 0.823946217 1.016355713 1.121281109 0.234134941 0.125233885 0.767901225 1.082614994 0.026419169 0.028010167 3.51E-08 7.454252477 0.104925396 ELT(ph)DEEAERLQLEIDQK ddPTM_HeLa_Curcumin_4h_R1 1 ELTDEEAERLQLEIDQK 17 1 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 1 0 ELT(1)DEEAERLQLEIDQK 70.02 0.016012 8395100 2660.4 1982.5 1814.9 2344 2348.6 2695.9 1706.4 1831.2 1870.1 1931.2 TRUE FALSE FALSE 2449.826533 2153.858466 1882.161791 2334.301149 2320.594479 2136.739951 1754.276991 2389.52445 1664.954709 1998.309056 1.225949772 1.077840517 0.941877226 1.168138203 1.161279068 1.069274017 0.877880719 1.195773218 0.833181786 1 10.96456401 -4.993491494 24.98272016 1.1024613 1.021014589 0 0.135444998 349.0902757 1339943.707 0.016221443 0.048496856 1.02E-05 4.993491494 -0.081446711 ELT(ph)PEKDISEEESAPGVLIVR ddPTM_HeLa_Curcumin_4h_R1 1 ELTPEKDISEEESAPGVLIVR 21 1 A0A087WUV0 A0A087WUV0 1 0 ELT(0.999)PEKDIS(0.001)EEESAPGVLIVR 82.755 0.00081754 6525300 1362.2 1244.1 1152.8 1355.4 1367.4 1669.8 1340.7 748.44 1419.7 1184.7 TRUE FALSE FALSE 1254.380433 1351.63446 1195.523782 1349.791714 1351.094648 1323.464657 1378.316434 976.6359106 1263.962462 1225.868237 1.023258777 1.10259359 0.975246561 1.101090373 1.102153239 1.07961412 1.124359366 0.796689139 1.031075302 1 10.2595882 -7.498308368 10.54904506 1.01022804 1.048338543 0.006509711 0.091972316 1.246925788 521.4144098 0.014838548 0.016247674 3.17E-08 7.498308368 0.038110503 ELTDEEAER ddPTM_HeLa_Curcumin_4h_R1 2 ELTDEEAER 9 0 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 0 0 ; ; 113.62 0.0024395 7542100 5673.3 4924.9 4921.8 5487.7 5821.5 6245.7 4741.8 5402.8 4634.6 4022.2 FALSE FALSE TRUE 5224.252319 5350.586411 5104.206238 5464.993351 5752.082415 4950.271416 4874.842146 7050.088849 4126.195975 4161.971151 1.255235111 1.2855895 1.226391547 1.313078143 1.382057253 1.189405509 1.171282061 1.693930254 0.991404271 1 12.02305125 -13.29756856 0.113883202 1.01E-10 1.493867706 0.529820704 0.130025137 58.15114951 0.509123443 13.6228918 0.718046788 5.04E-14 13.29756856 1.493867706 ELTIGSK ddPTM_HeLa_Curcumin_4h_R1 1 ELTIGSK 7 0 R4GN98;P06703 R4GN98 S100A6 Protein S100;Protein S100-A6 0 0 150.17 0.00084463 111710000 11750 9924 9690.1 9855.4 9603.2 11422 9263.4 9501.2 10846 9477.4 FALSE FALSE TRUE 10819.9751 10781.78634 10049.22363 9814.620966 9488.688112 9052.948448 9523.306073 12398.07214 9656.220935 9806.738945 1.103320397 1.099426262 1.024726332 1.000803735 0.967568135 0.923135458 0.971098153 1.264240051 0.984651574 1 13.25955776 -6.54005775 24.27889777 1.054338064 1.01339341 0.002026629 0.093465997 501.7321711 709088.9896 0.014653571 0.020726999 2.88E-07 6.54005775 -0.040944654 ELTIGSK(ac)LQDAEIAR ddPTM_HeLa_Curcumin_4h_R1 1 ELTIGSKLQDAEIAR 15 1 R4GN98;P06703 R4GN98 S100A6 Protein S100;Protein S100-A6 0 1 ELTIGSK(1)LQDAEIAR 201.08 3.40E-13 609970 520.48 403.39 689.7 612.71 473.45 89.632 383.76 589.39 510.09 677.91 FALSE TRUE FALSE 479.2834588 438.2572341 715.2608887 610.1747684 467.804418 71.04131284 394.5272728 769.0922978 454.1344032 701.467322 0.683258427 0.624772132 1.019663876 0.869854873 0.666894099 0.101275299 0.562431435 1.096405026 0.647406357 1 9.454232087 -5.603949999 5.278414838 0.842468436 0.554068688 0.118093588 0.258546396 0.250528039 12.01791433 0.038161071 0.077676268 2.49E-06 5.603949999 -0.288399747 ELTS(ph)SGGPTK ddPTM_HeLa_Curcumin_4h_R1 1 ELTSSGGPTK 10 0 Q96EE3;Q96EE3-1 Q96EE3 SEH1L Nucleoporin SEH1 1 0 ELT(0.007)S(0.962)S(0.029)GGPT(0.002)K 96.113 0.015156 4407000 7230.9 6123.8 6581.8 6652.4 7527.1 7812.6 5595.2 4610.8 7003 6715.5 TRUE FALSE FALSE 6658.566635 6653.113985 6825.727298 6624.874131 7437.344249 6192.178694 5752.186253 6016.611694 6234.788421 6948.863125 0.958223887 0.957439205 0.982279716 0.953375252 1.070296553 0.89110673 0.827788107 0.865841158 0.897238629 1 12.76256125 -5.040742083 8.193594046 0.981418027 0.84973974 0.60484403 0.042397108 0.101678111 19.18588697 0.004553638 0.011844142 9.10E-06 5.040742083 -0.131678287 FNS(ph)YDISR ddPTM_HeLa_Curcumin_4h_R1 1 FNSYDISR 8 0 B4DFB6;Q6IQ26-2;Q6IQ26 B4DFB6 DENND5A DENN domain-containing protein 5A 1 0 FNS(0.993)YDIS(0.007)R 113.67 0.010223 8446600 2759.3 2288.9 2324 2508.5 2420.7 2760 2647.7 3422.8 2148.3 1989.5 TRUE FALSE FALSE 2540.898493 2486.742317 2410.129484 2498.120492 2391.834734 2187.544888 2721.987336 4466.395963 1912.636865 2058.634977 1.234263734 1.207956896 1.170741541 1.213483944 1.161854705 1.06261912 1.322229228 2.169591022 0.929080136 1 11.00747233 -4.267461129 2.91550636 1.132855762 2.340682977 0.915672205 0.094935988 0.080725964 0.978299993 0.013800474 0.226612746 5.40E-05 4.267461129 1.207827215 up ELVGPPLAETVFT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 ELVGPPLAETVFTPK 15 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 ELVGPPLAETVFT(1)PK;ELVGPPLAETVFT(1)PK;ELVGPPLAETVFT(1)PK ;; 193.96 5.10E-06 83921000 13505.4 12208.1 14104.6 13473.8 15411.8 14503.7 11276.7 7719.2 11773.2 9655.2 TRUE FALSE FALSE 12436.43334 13263.31377 14627.32888 13418.04899 15228.02435 11495.46913 11593.09385 10072.74855 10481.70942 9990.717481 1.244798821 1.32756369 1.464091934 1.343051589 1.524217293 1.150614973 1.160386516 1.008210728 1.049144812 1 13.28637257 -8.720374352 0.839299256 1.014143157 1.286805714 0.325700854 0.144521413 0.505846409 0.707527316 0.074710043 0.031999948 1.90E-09 8.720374352 0.272662557 ELVGPPLAETVFT(ph)PKT(ph)SPENVQDR ddPTM_HeLa_Curcumin_4h_R1 2 ELVGPPLAETVFTPKTSPENVQDR 24 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 2 0 ELVGPPLAET(0.178)VFT(0.668)PKT(0.577)S(0.577)PENVQDR;ELVGPPLAET(0.073)VFT(0.799)PKT(0.564)S(0.564)PENVQDR ; 74.214 0.00040421 78317000 6109.6 4798.4 5401.1 5448.6 5149 5410 4732.9 2790.7 5546.5 4829.4 TRUE FALSE FALSE 5626.018713 5213.152315 5601.269517 5426.055137 5087.601538 4287.905017 4865.692436 3641.571583 4938.062827 4997.221291 1.125829413 1.043210219 1.120876822 1.08581446 1.018086101 0.858057862 0.973679602 0.728719296 0.988161728 1 12.28691039 -4.183259223 0.745139424 1.065996063 0.546523405 0.689653844 0.064546416 1.297918586 0.469988738 0.011238201 0.577398395 6.56E-05 4.183259223 -0.519472657 ELVGPPLAETVFT(ph)PKTS(ph)PENVQDR ddPTM_HeLa_Curcumin_4h_R1 2 ELVGPPLAETVFTPKTSPENVQDR 24 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 2 0 ELVGPPLAET(0.071)VFT(0.904)PKT(0.416)S(0.61)PENVQDR;ELVGPPLAET(0.068)VFT(0.879)PKT(0.213)S(0.84)PENVQDR ; 65.059 0.0034123 50364000 3605.1 3011 3569.3 3930.1 3370.1 3032.4 2955.3 2103.46 4120.6 3154 TRUE FALSE FALSE 3319.752531 3271.257423 3701.581398 3913.838288 3329.913759 2403.446058 3038.217764 2744.795271 3668.580489 3263.601265 1.017205308 1.002345923 1.134201484 1.199239113 1.02031881 0.73643986 0.930940246 0.841032665 1.124089676 1 11.67224909 -5.349345944 8.199233668 1.033239587 0.845974609 0.609655062 0.082252246 0.185532885 15.71072448 0.011791449 0.026439486 4.47E-06 5.349345944 -0.187264978 ELVLDNCK ddPTM_HeLa_Curcumin_4h_R1 1 ELVLDNCK 8 0 Q92688-2;Q92688 Q92688-2 ANP32B Acidic leucine-rich nuclear phosphoprotein 32 family member B 0 0 114.89 0.0037834 2178100 3824.2 2272.3 3080.5 2478.1 2886.5 4441.9 2756.5 2941.1 3221 3024.2 FALSE FALSE TRUE 3521.510535 2468.707487 3194.66604 2467.846279 2852.080373 3520.599869 2833.839971 3837.827851 2867.664359 3129.290725 1.125338246 0.788903206 1.020891416 0.788627998 0.911414318 1.125047232 0.905585393 1.226420997 0.916394356 1 11.61161998 -12.86196356 12.11389101 0.227292015 1.017144214 0 0.143367389 0 0 0 0.018392727 1.37E-13 12.86196356 0.789852199 ELVNDDEDIDWVQTEK ddPTM_HeLa_Curcumin_4h_R1 1 ELVNDDEDIDWVQTEK 16 0 P41743 P41743 PRKCI Protein kinase C iota type 0 0 186.68 3.29E-05 3516100 374.92 462.32 234.79 441.76 480.52 391.32 154.73 314.01 443.21 454.46 FALSE FALSE TRUE 345.2446864 502.2808807 243.4915239 439.9321142 474.7901128 310.1558209 159.0713074 409.7502035 394.5909719 470.2524512 0.734168818 1.068109011 0.517788952 0.935523277 1.009649416 0.659551737 0.338267896 0.87134092 0.839104551 1 8.877291654 -13.52287874 0.038246772 2.217014304 8.18E-09 0.112894597 0.210111282 924.4826902 2.825760292 139.1398524 47.45960318 3.00E-14 13.52287874 -2.217014296 ILGPSKPPPS(ph)T(ph)Y(ph)NPHK ddPTM_HeLa_Curcumin_4h_R1 1 ILGPSKPPPSTYNPHK 16 1 Q86XN7-2;Q86XN7 Q86XN7-2 PROSER1 Proline and serine-rich protein 1 3 0 ILGPSKPPPS(1)T(1)Y(1)NPHK 72.321 0.0063732 0 3176.1 2556.1 2985.9 2872 2676.3 3313.3 1490.4 824.62 3547.4 2621.1 TRUE FALSE FALSE 2924.708334 2777.037894 3096.560081 2860.116425 2644.38687 2626.084231 1532.216613 1076.042842 3158.259095 2712.18303 1.078359499 1.023912422 1.141722386 1.054544031 0.975003103 0.968254798 0.5649385 0.396744184 1.164471225 1 11.40523883 -4.690520652 2.132541053 1.043136973 0.385424807 0.940916527 0.058119019 0.048618649 0.399961324 0.006988311 0.043680359 2.04E-05 4.690520652 -0.657712167 down ELVSSSSSGSDS(ph)DSEVDKK ddPTM_HeLa_Curcumin_4h_R1 1 ELVSSSSSGSDSDSEVDKK 19 1 P53999;D6RC37;D6R970 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 1 0 ELVSS(0.001)S(0.003)S(0.012)S(0.062)GS(0.223)DS(0.663)DS(0.036)EVDKK 96.016 0.00063979 90182000 1814.5 1256 1459.6 1356.5 1432.5 1936.9 1121.3 658.14 1746 1344.8 TRUE FALSE FALSE 1670.88041 1364.563043 1513.69406 1350.887162 1415.418373 1535.165107 1152.76066 858.8038563 1554.468168 1391.5317 1.200749081 0.980619445 1.087789851 0.970791512 1.017165741 1.103219644 0.828411354 0.617164421 1.117091453 1 10.44245806 -4.515683302 2.415724928 1.074833389 0.605552251 0.79925803 0.070743641 0.135665188 1.332110201 0.012653593 0.104293306 3.05E-05 4.515683302 -0.469281137 EMDEAATAEER ddPTM_HeLa_Curcumin_4h_R1 1 EMDEAATAEER 11 0 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6;C9JF13;C9J6B6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 0 112.75 0.0036956 1060100 410.03 520.51 397.11 596.96 579.7 616.49 333.26 468.38 636.13 595.33 FALSE FALSE TRUE 377.5756928 565.5005651 411.8272459 594.4899377 572.7874561 488.6230247 342.6103787 611.1869058 566.3481305 616.0176732 0.612929968 0.91799406 0.668531544 0.96505338 0.92982309 0.793196439 0.556169723 0.99215807 0.919369939 1 9.266827931 -9.659420975 1.516603025 0.999547369 0.774771836 0.119664765 0.147862809 0.468926413 1.946747634 0.10466943 0.023748303 2.19E-10 9.659420975 -0.224775533 EMDEEDK(ac)AFK ddPTM_HeLa_Curcumin_4h_R1 2 EMDEEDKAFK 10 1 Q9Y2S6 Q9Y2S6 TMA7 Translation machinery-associated protein 7 0 1 ; EMDEEDK(1)AFK;EMDEEDK(1)AFK 102.06 0.0087862 6007500 2863.9 3452.7 2832.4 3197.3 5090 6520.5 4735 4434.6 6669.6 3331.6 FALSE TRUE FALSE 2637.219293 3751.136003 2937.371236 3184.07042 5029.305074 5168.074799 4867.851356 5786.689126 5937.961567 3447.372852 0.764993926 1.088114389 0.85206079 0.923622293 1.458880513 1.499134274 1.41204667 1.678579421 1.72245992 1 11.75128163 -5.749609553 4.851516487 0.900687059 1.511241986 0.308335615 0.279155485 0.048468751 2.960472218 0.017113993 0.033605847 1.78E-06 5.749609553 0.610554927 EMDESLANLS(ph)EDEYYS(ph)EEERNAK ddPTM_HeLa_Curcumin_4h_R1 1 EMDESLANLSEDEYYSEEERNAK 23 1 R4GMQ1;O60341;O60341-2 R4GMQ1 KDM1A Lysine-specific histone demethylase 1A 2 0 EMDES(0.047)LANLS(0.763)EDEY(0.284)Y(0.284)S(0.621)EEERNAK 52.402 0.013712 13573000 3929.4 2339.3 2436.6 3349.3 1872.6 3696.3 2423.4 2109.6 5660.9 3888.3 TRUE FALSE FALSE 3618.383844 2541.498668 2526.902539 3335.441484 1850.270468 2929.645714 2491.394082 2752.807329 5039.913433 4023.418136 0.899330798 0.631676496 0.628048702 0.829006922 0.459875262 0.728148459 0.619223257 0.684196182 1.252644707 1 11.97420596 -7.368832599 3.037771859 0.95877462 0.653066956 0.647290472 0.129198696 0.098261181 1.679913912 0.015393786 0.017530997 4.28E-08 7.368832599 -0.305707665 EMDESLANLSEDEY(ph)YS(ph)EEERNAK ddPTM_HeLa_Curcumin_4h_R1 1 EMDESLANLSEDEYYSEEERNAK 23 1 R4GMQ1;O60341;O60341-2 R4GMQ1 KDM1A Lysine-specific histone demethylase 1A 2 0 EMDESLANLS(0.007)EDEY(0.642)Y(0.642)S(0.71)EEERNAK 68.134 0.0006678 9686600 2392.8 1418.4 1606.1 2033.5 1282.3 2146 1784.4 1314.3 3566.6 2647.5 TRUE FALSE FALSE 2203.407355 1541.000176 1665.623479 2025.085916 1267.00941 1700.89541 1834.465462 1715.02402 3175.352903 2739.500428 0.804309915 0.562511383 0.608002635 0.739217229 0.462496518 0.62087795 0.669635034 0.626035317 1.159099254 1 11.41969711 -7.841120439 0.794815993 0.968363454 0.606231301 0.759799266 0.098419006 0.172799216 0.237439155 0.024157104 0.019826591 1.44E-08 7.841120439 -0.362132153 EMDKENNDGS(ph)SEIGK ddPTM_HeLa_Curcumin_4h_R1 1 EMDKENNDGSSEIGK 15 1 Q9HAW4-2;Q9HAW4-3;Q9HAW4 Q9HAW4-2 CLSPN Claspin 1 0 EMDKENNDGS(0.756)S(0.244)EIGK 60.938 0.019546 6107700 1554.6 984.86 1397.9 1340.3 1480.6 1560.7 1005.7 938.19 1431 1287.8 TRUE FALSE FALSE 1431.55177 1069.98691 1449.707404 1334.754194 1462.944812 1236.993227 1033.917235 1224.239812 1274.02288 1332.550954 1.074294206 0.802961348 1.087918927 1.0016534 1.097852812 0.928289626 0.775893208 0.918718949 0.956078172 1 10.37997498 -5.01116862 6.609208082 1.022879378 0.847567013 0.321959184 0.087476151 0.096041824 20.74563491 0.011423174 0.031858329 9.75E-06 5.01116862 -0.175312365 EMDMSPEEVVAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 EMDMSPEEVVASPR 14 0 Q13049 Q13049 TRIM32 E3 ubiquitin-protein ligase TRIM32 1 0 EMDMSPEEVVAS(1)PR;EMDMSPEEVVAS(1)PR ; 222.88 1.96E-14 27958100 6265.4 5664.2 5446.5 5560.2 5858.6 6612.1 3850.14 4126.38 5614.1 4968 TRUE FALSE FALSE 5769.486979 6153.788209 5648.352081 5537.193366 5788.740021 5240.675926 3958.164566 5384.494266 4998.247276 5140.63763 1.122329056 1.197086558 1.098764879 1.077141352 1.12607432 1.019460289 0.76997541 1.047437041 0.972301033 1 12.3277316 -4.988220538 24.58669863 1.078104665 0.905209037 0.393932014 0.086401987 132.1125982 275746.8362 0.011649401 0.034909061 1.03E-05 4.988220538 -0.172895629 EMDMSPEEVVAS(ph)PRAS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 1 EMDMSPEEVVASPRASPAK 19 1 Q13049 Q13049 TRIM32 E3 ubiquitin-protein ligase TRIM32 2 0 EMDMSPEEVVAS(1)PRAS(1)PAK 75.225 0.0050577 16951000 4640.9 3324 3793.9 4052.5 3736.4 4840.3 3333.2 1760.1 4831.9 4107.7 TRUE FALSE FALSE 4273.567868 3611.311749 3934.505271 4035.731829 3691.84587 3836.367219 3426.720621 2296.746387 4301.852659 4250.442269 1.005440751 0.849631996 0.925669618 0.949485153 0.868579229 0.902580714 0.806203309 0.540354684 1.012095304 1 12.05339725 -3.684024976 0.599994639 0.986870233 4.68E-41 0.825240814 0.05553912 1.815594986 0.274458666 0.010473617 1.450592839 0.000207002 3.684024976 -0.986870233 EMDRETLIDVAR ddPTM_HeLa_Curcumin_4h_R1 1 EMDRETLIDVAR 12 1 P40227;P40227-2 P40227 CCT6A T-complex protein 1 subunit zeta 0 0 142.76 0.000888 31738000 3532.8 3171 3000.7 3152.8 3499.8 3713.7 3641.2 2803.8 4067.8 3615.1 FALSE FALSE TRUE 3253.175152 3445.08711 3111.908582 3139.754549 3458.067171 2943.436758 3743.362272 3658.665713 3621.572517 3740.724456 0.86966447 0.92096789 0.831899975 0.839343979 0.924437823 0.786862757 1.000705162 0.978063409 0.968147363 1 11.86910198 -9.307612633 0.939079554 1.002634209 0.890701856 0.239118322 0.063209797 0.609569131 0.926855011 0.047801949 0.01161433 4.92E-10 9.307612633 -0.111932353 EMDT(ph)ARTPLSEAEFEEIMNR ddPTM_HeLa_Curcumin_4h_R1 2 EMDTARTPLSEAEFEEIMNR 20 1 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 1 0 EMDT(0.891)ART(0.109)PLSEAEFEEIMNR;EMDT(0.934)ART(0.066)PLSEAEFEEIMNR ; 90.872 0.00060907 27909000 2413.1 2475.79 2584.43 2161.48 2410 3446.1 2664.34 2261.07 2494.62 2205.87 TRUE FALSE FALSE 2222.100589 2689.786256 2680.211249 2152.536368 2381.262324 2731.340014 2739.09421 2950.459834 2220.966427 2282.523818 0.973527886 1.178426369 1.174231448 0.943051 1.043258478 1.19663155 1.200028752 1.292630469 0.973030997 1 11.1564142 -1.000000003 0.283160473 0.985051152 3.417323697 0.546074833 0.079151196 26.04381925 0.332267264 0.035427601 31.88778107 0.099999999 1.000000003 2.432272545 EMDTART(ph)PLSEAEFEEIMNR ddPTM_HeLa_Curcumin_4h_R1 2 EMDTARTPLSEAEFEEIMNR 20 1 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 1 0 EMDT(0.447)ART(0.553)PLSEAEFEEIMNR;EMDT(0.147)ART(0.853)PLSEAEFEEIMNR ; 102.84 0.00032248 59301000 4789.1 3668.7 3746.8 4473 4291 5609.6 4439.6 4308.2 4217.3 3499.4 TRUE FALSE FALSE 4410.037682 3985.806081 3885.659704 4454.491911 4239.832628 4446.105727 4564.163227 5621.750347 3754.672741 3621.00389 1.217904707 1.100746147 1.073089072 1.230181476 1.170899772 1.227865493 1.260469021 1.552539163 1.03691486 1 11.82217401 -1 0.44926411 1.09781316 10.42440711 0.801531858 0.066329116 32.33810228 0.34950724 0.018463605 278.9066031 0.1 1 9.326593947 EMEAELEDER ddPTM_HeLa_Curcumin_4h_R1 3 EMEAELEDER 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ;; ;; 234.2 1.88E-15 185371600 10044.1 7704.4 8610.5 8391.9 8768.1 9514.2 8400 7331.2 8954.7 7698.3 FALSE FALSE TRUE 9249.098887 8370.334006 8929.612705 8357.176541 8663.546134 7540.847673 8635.681393 9566.449131 7972.391814 7965.815352 1.16109883 1.050781827 1.120991676 1.049130086 1.08759063 0.946651076 1.08409259 1.200937846 1.000825585 1 12.95960632 -9.658491258 1.516386321 1.000211056 1.093818971 0.218119363 0.065132199 0.518153115 2.151239899 0.048134113 0.010937721 2.20E-10 9.658491258 0.093607915 EMEAELEDERK ddPTM_HeLa_Curcumin_4h_R1 3 EMEAELEDERK 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ;; ;; 123.62 0.0054627 83889000 9781.2 8698.6 9243 9368.7 9523.2 10432.8 8591.7 7886.3 9793.9 8609 FALSE FALSE TRUE 9007.007699 9450.468224 9585.553711 9329.934802 9409.64206 8268.919678 8832.759979 10290.79657 8719.533673 8908.162109 1.01109607 1.060877441 1.076041679 1.047346769 1.056294435 0.928240817 0.991535613 1.155209845 0.978825213 1 13.1209121 -7.420497668 6.01176218 1.004820018 1.040188815 0.129577949 0.055549167 0.476653609 23.34017375 0.009451949 0.01073461 3.80E-08 7.420497668 0.035368796 EMEAELEDERKQR ddPTM_HeLa_Curcumin_4h_R1 1 EMEAELEDERKQR 13 2 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 89.266 0.0050707 7773200 3287 2236.5 1831.8 2510.7 1519.7 2862.1 2093.3 2069.7 4149.6 3496.5 FALSE FALSE TRUE 3026.830482 2429.813094 1899.688119 2500.311389 1501.57857 2268.468197 2152.032364 2700.742002 3694.399262 3618.003115 0.836602509 0.671589553 0.525065363 0.691074969 0.415029651 0.62699454 0.594812192 0.7464731 1.021115556 1 11.82097793 -7.488896005 1.070541202 0.954994403 0.591177455 0.752189364 0.091975423 0.155729849 0.359273169 0.020197289 0.021469187 3.24E-08 7.488896005 -0.363816948 EMEENFAVEAANYQDTIGR ddPTM_HeLa_Curcumin_4h_R1 4 EMEENFAVEAANYQDTIGR 19 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 0 ;;; ;;; 207.85 1.04E-12 45842900 5022.23 4146.71 4202.47 4539.3 5298.77 5769.72 4501.22 4270.65 5525.72 4101.87 FALSE FALSE TRUE 4624.715196 4505.133135 4358.217235 4520.517579 5235.585628 4573.015034 4627.512119 5572.751525 4919.562341 4244.409677 1.089601511 1.061427496 1.026813519 1.065052133 1.233525043 1.077420744 1.090260477 1.312962685 1.159068684 1 12.0513482 -1 0.263975568 1.026478395 2.466417177 0.337891979 0.074621563 29.57779236 0.373615396 0.031117416 19.50334408 0.1 1 1.439938782 EMEHNTVCAAGT(ph)SPVGEIGEEK ddPTM_HeLa_Curcumin_4h_R1 2 EMEHNTVCAAGTSPVGEIGEEK 22 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 0 EMEHNTVCAAGT(0.5)S(0.5)PVGEIGEEK;EMEHNTVCAAGT(0.999)S(0.001)PVGEIGEEK ; 127.94 1.12E-05 196601000 7567 7897.4 6802.2 6127.5 10019.6 13473.2 7436.4 8165.1 11120.6 7712.3 TRUE FALSE FALSE 6968.063965 8580.016066 7054.295516 6102.146029 9900.122814 10678.70645 7645.04537 10654.6014 9900.698002 7980.301851 0.873157945 1.075149315 0.883963495 0.76465103 1.240569968 1.338133149 0.957989499 1.335112581 1.240642044 1 12.9622276 -5.742298864 24.98003772 0.934317648 1.207967113 0.350486889 0.158020945 142.4871952 185957.1489 0.017580597 0.035117454 1.81E-06 5.742298864 0.273649464 EMEHNTVCAAGTS(ph)PVGEIGEEK ddPTM_HeLa_Curcumin_4h_R1 2 EMEHNTVCAAGTSPVGEIGEEK 22 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 0 EMEHNTVCAAGT(0.336)S(0.664)PVGEIGEEK;EMEHNT(0.003)VCAAGT(0.281)S(0.716)PVGEIGEEK ; 99.836 7.19E-05 260950000 4787.3 4436.5 3455.9 3116.3 7014.1 10909.8 5470.8 2937.6 7132.5 3752.3 TRUE FALSE FALSE 4408.380153 4819.971291 3583.978694 3103.405576 6930.461439 8646.984501 5624.295924 3833.260717 6350.082595 3882.692146 1.135392657 1.241399295 0.923065378 0.799292208 1.784962902 2.227059004 1.448555722 0.987268775 1.635484441 1 11.92284161 -5.754795274 24.99967451 1.051933394 1.644225347 0.2945656 0.359987135 110.6706407 416414.8162 0.045637943 0.089615531 1.76E-06 5.754795274 0.592291953 EMFEDTVEER ddPTM_HeLa_Curcumin_4h_R1 2 EMFEDTVEER 10 0 E9PC52;Q16576 E9PC52 RBBP7 Histone-binding protein RBBP7 0 0 ; ; 189.18 0.0011136 66343000 4454.2 3527 3804.5 3755.4 4050.1 5171.7 3920.8 3825.9 4303.7 3876.3 FALSE FALSE TRUE 4101.64537 3831.858164 3945.498117 3739.86115 4001.805203 4099.031123 4030.807096 4992.399298 3831.594877 4011.001136 1.022598905 0.955337093 0.98366916 0.93240092 0.997707322 1.021947136 1.004937909 1.24467661 0.955271451 1 11.96974666 -4.260639561 6.00780887 0.999539618 1.251352254 0.85784611 0.031162888 0.036246837 6.260744407 0.004251972 0.036989891 5.49E-05 4.260639561 0.251812635 EMIDKWEDRWEWLR ddPTM_HeLa_Curcumin_4h_R1 1 EMIDKWEDRWEWLR 14 2 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 69.352 0.013108 8134300 4952.3 4658 4513 4005.4 3970.4 8508 5891.7 5164.6 5626 5183 FALSE FALSE TRUE 4560.320229 5060.616764 4680.25575 3988.826716 3923.055573 6743.344895 6057.005245 6739.262765 5008.841876 5363.108864 0.850312821 0.943597621 0.87267588 0.743752703 0.731489081 1.257357452 1.129383236 1.256596302 0.933943726 1 12.38885382 -5.247618525 24.96274916 0.898850054 1.205939446 0.754833189 0.089242295 373.1193156 673913.8257 0.014753399 0.037396476 5.65E-06 5.247618525 0.307089392 EMK(ac)MWEEK ddPTM_HeLa_Curcumin_4h_R1 1 EMKMWEEK 8 1 H0Y896;Q96MT7 H0Y896 CFAP44 Cilia- and flagella-associated protein 44 0 1 EMK(1)MWEEK 73.248 0.011823 4991700 968.14 1819.6 1207.8 1587.7 791.52 0 386.99 331.5 1071.2 2261.2 FALSE TRUE FALSE 891.5106974 1976.878116 1252.56213 1581.130518 782.081641 0 397.8478979 432.572824 953.69204 2339.776532 0.381023865 0.844900395 0.535334086 0.675761337 0.334254845 0 0.170036708 0.184877837 0.407599626 1 11.19215503 -11.16859551 0.12950206 2.118552626 1.89E-18 0.254103918 0.257319811 22.56190169 0.392569582 8.432597119 1.034381156 6.78E-12 11.16859551 -2.118552626 EMLAS(ph)DDEEDVSSK ddPTM_HeLa_Curcumin_4h_R1 6 EMLASDDEEDVSSK 14 0 E7ETM8;Q0ZGT2-4;E7EUA0;Q0ZGT2-2;Q0ZGT2;Q0ZGT2-3 E7ETM8 NEXN Nexilin 1 0 EMLAS(1)DDEEDVSSK;EMLAS(1)DDEEDVSSK;EMLAS(1)DDEEDVSSK;EMLAS(1)DDEEDVSSK;EMLAS(1)DDEEDVSSK;EMLAS(1)DDEEDVSSK ;;;;; 176.56 1.62E-06 404237200 21218.7 17608.99 22234.6 18926 24477.9 23108.8 21119.4 20504.5 18016.5 15951.6 TRUE FALSE FALSE 19539.21751 19131.03263 23058.63384 18847.68923 24186.01703 18315.77439 21711.95352 26756.22766 16040.13503 16505.91691 1.183770499 1.15904089 1.396991997 1.141874718 1.465293758 1.109649012 1.315404266 1.62100826 0.971780914 1 14.01069566 -1.000000004 0.071467671 0.668323361 2.655176074 0.562427443 0.130970642 123.7319369 0.658226376 3.201176133 24.78651971 0.099999999 1.000000004 1.986852713 EMLAS(ph)DDEEDVSSKVEK ddPTM_HeLa_Curcumin_4h_R1 3 EMLASDDEEDVSSKVEK 17 1 E7ETM8;Q0ZGT2-4;E7EUA0;Q0ZGT2-2;Q0ZGT2;Q0ZGT2-3 E7ETM8 NEXN Nexilin 1 0 EMLAS(1)DDEEDVSSKVEK;EMLAS(1)DDEEDVSSKVEK;EMLAS(1)DDEEDVSSKVEK ;; 133.35 0.00015184 346201000 10501.8 9183.6 9338.4 9983.9 9876.7 12137.5 9777.7 11946.2 10688.2 9959.2 TRUE FALSE FALSE 9670.571449 9977.389463 9684.489319 9942.589267 9758.926803 9620.045682 10052.03595 15588.54139 9515.731201 10305.28146 0.93840925 0.968182141 0.939759807 0.964805212 0.946983044 0.93350635 0.975425658 1.512674976 0.923383921 1 13.33109629 -4.261615776 6.44770648 0.963452551 1.523964568 0.981333053 0.023071429 0.012448097 3.036645204 0.003637293 0.030349449 5.48E-05 4.261615776 0.560512016 EMLMEDVGS(ph)EEEQEEEDEAPFQEK ddPTM_HeLa_Curcumin_4h_R1 7 EMLMEDVGSEEEQEEEDEAPFQEK 24 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 EMLMEDVGS(1)EEEQEEEDEAPFQEK;EMLMEDVGS(1)EEEQEEEDEAPFQEK;EMLMEDVGS(1)EEEQEEEDEAPFQEK;EMLMEDVGS(1)EEEQEEEDEAPFQEK;EMLMEDVGS(1)EEEQEEEDEAPFQEK;EMLMEDVGS(1)EEEQEEEDEAPFQEK;EMLMEDVGS(1)EEEQEEEDEAPFQEK ;;;;;; 164.39 7.19E-10 52720200 27705.9 23973.7 25953.9 24314.1 28655.4 30046.7 26825.5 29318.7 23806.3 24031.2 TRUE FALSE FALSE 25512.94878 26045.8798 26915.77437 24213.4947 28313.70307 23814.67572 27578.15133 38257.83666 21194.80845 24866.28241 1.026005752 1.047437625 1.082420521 0.973748078 1.138638362 0.957709533 1.109058076 1.538542675 0.852351313 1 14.60190322 -4.273506536 3.266101704 1.02337166 1.603521558 0.820403199 0.073700877 0.05986533 1.029042768 0.00633993 0.086045544 5.33E-05 4.273506536 0.580149898 EMLQQSK ddPTM_HeLa_Curcumin_4h_R1 1 EMLQQSK 7 0 P08238;Q58FF7;P07900;P07900-2 P08238;P07900 HSP90AB1;HSP90AB3P;HSP90AA1 Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Heat shock protein HSP 90-alpha 0 0 145.63 0.0022302 8330700 6833.7 6543.4 5913 4937.4 5762.4 6217.1 5295.7 5079.9 5491.3 6512.5 FALSE FALSE TRUE 6292.805434 7108.982339 6132.140982 4916.970347 5693.687144 4927.603379 5444.283089 6628.738125 4888.918129 6738.80889 0.933815684 1.054931584 0.909974015 0.729649769 0.844910018 0.731227649 0.807899909 0.983666139 0.725486983 1 12.7182779 -6.515572853 22.27566723 0.974723416 0.815786052 0.145117016 0.10701785 47.12040662 143670.0933 0.011040028 0.016019605 3.05E-07 6.515572853 -0.158937365 EMLQQSK(ac)ILK ddPTM_HeLa_Curcumin_4h_R1 3 EMLQQSKILK 10 1 P08238;Q58FF7;P07900;P07900-2 P08238;P07900 HSP90AB1;HSP90AB3P;HSP90AA1 Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Heat shock protein HSP 90-alpha 0 1 ;; EMLQQSK(1)ILK;EMLQQSK(1)ILK;EMLQQSK(1)ILK 151.22 2.79E-06 13624200 4921.03 3945.71 3961.2 4171.61 4111.94 5651.75 3989.42 4109.9 4714.87 4136.62 FALSE TRUE FALSE 4531.525283 4286.759591 4108.005557 4154.348983 4062.907801 4479.513342 4101.352388 5362.98959 4197.660557 4280.367237 1.058676752 1.001493412 0.959732034 0.970559009 0.94919608 1.046525472 0.958177689 1.252927446 0.980677667 1 12.06351886 -4.253718048 24.77264755 1.010678977 1.25292758 0.790386067 0.039279755 334.1149025 1071925.116 0.006057971 0.087375554 5.58E-05 4.253718048 0.242248603 EMLWGSSTQLASDGS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 EMLWGSSTQLASDGSPK 17 0 A0A0J9YW64;A6NIW2;Q5JSL3 A0A0J9YW64 DOCK11 Dedicator of cytokinesis protein 11 1 0 EMLWGSSTQLAS(0.121)DGS(0.879)PK;EMLWGSSTQLAS(0.038)DGS(0.962)PK ; 203.89 1.25E-10 24559000 2515.8 2402.7 2336.22 2133.36 2472.2 2398.6 2125.52 1853.64 2409.4 2282.28 TRUE FALSE FALSE 2316.671775 2610.378682 2422.802368 2124.532722 2442.72063 1901.103322 2185.156371 2418.806303 2145.094848 2361.58906 0.980980059 1.105348397 1.025920389 0.899619988 1.034354652 0.805010217 0.92529069 1.024228281 0.908326891 1 11.20554223 -6.268174081 24.81584427 1.003563541 0.93500928 0.162762273 0.075185678 613.3628375 2260100.073 0.010358719 0.016045294 5.39E-07 6.268174081 -0.068554261 EMNPALGIDCLHK ddPTM_HeLa_Curcumin_4h_R1 2 EMNPALGIDCLHK 13 0 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 0 ; ; 115.91 0.00021919 7361100 4021 3169.9 3571.9 3185.3 3187.7 4943.1 3531 2942.34 4135 3651.6 FALSE FALSE TRUE 3702.733607 3443.892031 3704.277756 3172.120073 3149.688759 3917.84534 3630.070357 3839.445921 3681.400845 3778.492828 0.979949884 0.911445962 0.980358552 0.83951994 0.833583363 1.036880449 0.960719134 1.016131589 0.974304045 1 11.88359517 -7.430512621 4.910157149 0.991421871 0.938016075 0.095056923 0.063160392 0.358222609 13.8639759 0.01122533 0.012675635 3.71E-08 7.430512621 -0.053405796 VLSS(ph)TSEEDEPGVVK ddPTM_HeLa_Curcumin_4h_R1 1 VLSSTSEEDEPGVVK 15 0 Q8NI08-2;Q8NI08;Q8NI08-7;Q8NI08-4;Q8NI08-3 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 0 VLS(0.185)S(0.404)T(0.404)S(0.006)EEDEPGVVK 206.67 1.36E-09 16882000 2166.2 1669.7 1835.1 2163.9 1739.6 2268.9 3277.7 5585.5 1583.1 1595.2 TRUE FALSE FALSE 1994.742984 1814.021428 1903.11042 2154.946355 1718.856406 1798.304564 3369.663441 7288.493238 1409.437891 1650.633081 1.208471469 1.098985261 1.152957881 1.305527182 1.041331611 1.089463543 2.041436997 4.415574436 0.853877162 1 10.68880374 -4.266939252 2.113123531 1.112011669 5.311321113 0.985064535 0.12366778 0.048313661 0.237916183 0.015682009 0.382752644 5.41E-05 4.266939252 4.199309443 up EMQENDASMR ddPTM_HeLa_Curcumin_4h_R1 1 EMQENDASMR 10 0 P31930 P31930 UQCRC1 "Cytochrome b-c1 complex subunit 1, mitochondrial" 0 0 142.36 0.0071185 4836500 933.69 1023.9 942.72 1031.5 1035.7 1046.9 912.98 722.31 1237.8 887.91 FALSE FALSE TRUE 859.7874513 1112.401354 977.6580325 1027.231926 1023.349954 829.761139 938.5957616 942.5389939 1102.016437 918.7648064 0.935807995 1.210757471 1.064100438 1.118057548 1.11383234 0.903126821 1.021584365 1.02587625 1.199454343 1 9.843551785 EMQPTHPIR ddPTM_HeLa_Curcumin_4h_R1 6 EMQPTHPIR 9 0 P27348;P31946-2;P31946;P63104;E7EX29;B0AZS6;P63104-2;B7Z2E6;H0YB80 P27348;P31946-2;P63104 YWHAQ;YWHAB;YWHAZ "14-3-3 protein theta;14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed;14-3-3 protein zeta/delta" 0 0 ;;;;; ;;;;; 144.77 3.04E-06 50768900 13453.51 11617.37 11607.44 11410.52 10875.22 11900.42 9968.4 10288.73 12417.8 10907.47 FALSE FALSE TRUE 12388.65049 12621.5237 12037.62194 11363.30629 10745.5401 9432.138747 10248.08648 13425.71641 11055.59841 11286.50377 1.097651739 1.11828463 1.066550119 1.006804811 0.952069864 0.835700669 0.907994777 1.189537228 0.979541462 1 13.46231103 -5.995060082 3.484767384 1.054994405 0.957781963 0.138864113 0.092670194 0.304855409 7.898130398 0.013947892 0.025401531 1.01E-06 5.995060082 -0.097212441 EMWTEVPK ddPTM_HeLa_Curcumin_4h_R1 1 EMWTEVPK 8 0 P62316;K7EJB5;P62316-2 P62316 SNRPD2 Small nuclear ribonucleoprotein Sm D2 0 0 100.15 0.013281 1302000 1718.7 1430.3 1363.4 1533.7 1818.2 1906.9 1495.1 1793.6 1688.1 1413.4 FALSE FALSE TRUE 1582.663081 1553.928759 1413.928803 1527.353956 1796.519153 1511.387445 1537.048482 2340.460383 1502.919653 1462.515545 1.082151289 1.062504097 0.96677865 1.044333485 1.228376108 1.033416329 1.050962151 1.600297783 1.027626447 1 10.51423624 -4.261449301 9.933503436 1.049507421 1.601690403 0.860583893 0.065793656 0.019787627 61.62913789 0.009392723 0.072847118 5.48E-05 4.261449301 0.552182983 ENAEVDGDDDAEEMEAK ddPTM_HeLa_Curcumin_4h_R1 3 ENAEVDGDDDAEEMEAK 17 0 P05198 P05198 EIF2S1 Eukaryotic translation initiation factor 2 subunit 1 0 0 ;; ;; 289.61 6.98E-79 223342000 7551 6248.2 6870.9 7051.4 8558.5 7211.73 6716.3 6334.99 6178.85 5867.35 FALSE FALSE TRUE 6953.330382 6788.266567 7125.541598 7022.223175 8456.445477 5715.935905 6904.741302 8266.499288 5501.045614 6071.239976 1.145289992 1.118102166 1.173655073 1.156637393 1.39286958 0.941477512 1.137286836 1.361583354 0.906082717 1 12.56777548 -13.52287873 0.147319263 0.330009154 1.237954099 0.365320473 0.120359047 69.07471884 0.697558531 13.27921114 0.28262996 3.00E-14 13.52287873 0.907944945 ENARS(ph)PSSVTGNALWK ddPTM_HeLa_Curcumin_4h_R1 2 ENARSPSSVTGNALWK 16 1 Q9NYB0;A0A590UJT3 Q9NYB0 TERF2IP Telomeric repeat-binding factor 2-interacting protein 1 1 0 ENARS(0.998)PS(0.001)SVT(0.001)GNALWK;ENARS(0.993)PS(0.003)S(0.001)VT(0.003)GNALWK ; 113.52 0.0015333 0 3214.3 2630.6 2740.7 3106.3 2999.7 3737.7 2845.2 3225.3 3067 2888.75 TRUE FALSE FALSE 2959.884763 2857.977342 2842.272753 3093.446954 2963.930537 2962.458887 2925.028655 4208.679123 2730.557773 2989.133847 0.990214863 0.956122237 0.950868344 1.034897436 0.991568357 0.991076024 0.978553924 1.407992863 0.913494648 1 11.54551178 -4.260405394 24.99975703 0.990960978 1.407992995 0.937416154 0.033149936 10.12435917 244753.0233 0.00307748 0.025242564 5.49E-05 4.260405394 0.417032017 ENAS(ph)PAPGTTAEEAMSR ddPTM_HeLa_Curcumin_4h_R1 3 ENASPAPGTTAEEAMSR 17 0 P46379-3;P46379;P46379-2;P46379-5;A0A0G2JK23;A0A024RCR6;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 0 ENAS(0.994)PAPGT(0.001)T(0.005)AEEAMSR;ENAS(0.965)PAPGT(0.032)T(0.003)AEEAMSR;ENAS(0.999)PAPGT(0.001)TAEEAMSR ;; 154.31 0.00018436 106890000 10613.8 10212.8 10700.4 9518.6 11361.1 11317.5 8095.2 7681.6 9540.1 9095.5 TRUE FALSE FALSE 9773.70653 11095.54892 11096.96624 9479.214555 11225.6263 8970.122925 8322.329525 10023.68448 8493.574898 9411.567948 1.038478029 1.178926719 1.179077312 1.007187602 1.19274773 0.953095486 0.884265998 1.065038741 0.902461199 1 13.20021938 -3.902524445 20.58069257 1.037723338 3.835570384 0.005933571 0.107384742 4844.269279 1087062.207 0.013650252 39956.71782 0.000125163 3.902524445 2.797847046 ENASPAPGTTAEEAMS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 ENASPAPGTTAEEAMSR 17 0 P46379-3;P46379;P46379-2;P46379-5;A0A0G2JK23;A0A024RCR6;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 0 ENAS(0.003)PAPGT(0.004)T(0.004)AEEAMS(0.988)R 72.152 0.020041 17307000 3304 3257.5 3048.5 2859.7 3358.3 3358.5 2704.5 2421.4 2999.5 2540.8 TRUE FALSE FALSE 3042.484914 3539.063785 3161.480092 2847.867319 3318.254466 2661.909242 2780.380991 3159.673713 2670.462354 2629.092611 1.157237634 1.346116059 1.202498565 1.083213009 1.262129167 1.012482113 1.057543953 1.201811492 1.015735369 1 11.36034925 -8.937160392 0.990480516 1.008743973 1.161445708 0.307313909 0.09356169 0.501101025 0.955443939 0.046661058 0.018501118 1.16E-09 8.937160392 0.152701735 ENDEEMKAAK(ac)EK ddPTM_HeLa_Curcumin_4h_R1 4 ENDEEMKAAKEK 12 2 O95696-2;O95696;J3KQ61 O95696-2 BRD1 Bromodomain-containing protein 1 0 1 ;;; ENDEEMK(0.011)AAK(0.989)EK;ENDEEMK(0.002)AAK(0.998)EK;ENDEEMKAAK(1)EK;ENDEEMKAAK(1)EK 121.21 0.00022575 100972600 22074.7 17728.7 18476.7 20586.1 16970.9 23914.2 18189.2 14236 26022.1 22150.8 FALSE TRUE FALSE 20327.4642 19261.08983 19161.46276 20500.92017 16768.5331 18954.12535 18699.54 18576.49087 23167.54073 22920.53865 0.886866775 0.840341936 0.835995307 0.894434484 0.731594198 0.826949385 0.815842083 0.810473573 1.010776452 1 14.48435333 -8.243497914 0.348878201 1.027579998 0.794982117 0.805032257 0.036116412 0.481120013 0.138943122 0.045235895 0.020302707 5.71E-09 8.243497914 -0.23259788 ENDFAQSGQDAVPES(ph)PSKLSSK ddPTM_HeLa_Curcumin_4h_R1 2 ENDFAQSGQDAVPESPSKLSSK 22 1 O60285;F8VZ96 O60285 NUAK1 NUAK family SNF1-like kinase 1 1 0 ENDFAQS(0.005)GQDAVPES(0.82)PS(0.053)KLS(0.061)S(0.061)K;ENDFAQSGQDAVPES(0.998)PS(0.001)KLSS(0.001)K ; 108.5 0.0001436 16347000 4343.2 3302.2 3734.1 4762.9 3842.4 5034.8 3628.6 2878.78 4700.1 3903.1 TRUE FALSE FALSE 3999.431137 3587.627454 3872.489031 4743.192382 3796.58189 3990.525726 3730.40875 3756.50677 4184.510789 4038.732434 0.990268903 0.888305307 0.958837728 1.174426001 0.940042935 0.988063901 0.923658304 0.930120237 1.036095076 1 11.97968686 -4.836821756 2.280657752 0.994519893 0.923558432 0.132904152 0.070637458 0.50319519 5.05669818 0.009672514 0.044718931 1.46E-05 4.836821756 -0.070961461 TFS(ph)DGLATR ddPTM_HeLa_Curcumin_4h_R1 2 TFSDGLATR 9 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 0 T(0.078)FS(0.911)DGLAT(0.011)R;T(0.032)FS(0.95)DGLAT(0.019)R ; 111.5 0.0086668 45786000 5417.8 3988.3 5029.2 5070.5 4066.6 4568.7 4892.7 7449.5 4581.1 4122.8 TRUE FALSE FALSE 4988.975413 4333.03088 5215.586576 5049.519615 4018.108451 3621.10012 5029.975994 9720.818257 4078.564791 4266.066993 1.169455478 1.015696867 1.222574935 1.18364752 0.941876548 0.84881464 1.17906634 2.278637038 0.956047994 1 12.05869091 -4.266740123 4.409084468 1.070617221 2.358339978 0.910261873 0.115433965 0.041412833 1.958703361 0.016387424 0.164594969 5.41E-05 4.266740123 1.287722757 up ENGDLS(ph)PFSGTSLR ddPTM_HeLa_Curcumin_4h_R1 1 ENGDLSPFSGTSLR 14 0 V9GY71;V9GYH5;P19174 V9GY71 PLCG1 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1" 1 0 ENGDLS(0.998)PFS(0.001)GT(0.001)SLR 109.48 0.0030511 3184600 693.8 814.48 691.76 742.28 966.81 739.68 680.02 764.04 897.11 683.47 TRUE FALSE FALSE 638.8849979 884.8800219 717.3972341 739.208642 955.2814222 586.2620301 699.099531 996.9922788 798.6992775 707.2205316 0.903374505 1.25120805 1.014389716 1.045230743 1.350754651 0.82896636 0.988517018 1.409733222 1.129349675 1 9.466016349 -7.283816186 24.92760477 0.954371292 1.111317618 0.051970432 0.176015942 998.6925324 1112533.714 0.027321632 0.031255031 5.20E-08 7.283816186 0.156946326 ENGEEGCHQNGLALPVVEEGEVLS(ph)HSLEAEHR ddPTM_HeLa_Curcumin_4h_R1 1 ENGEEGCHQNGLALPVVEEGEVLSHSLEAEHR 32 0 Q9HC44 Q9HC44 GPBP1L1 Vasculin-like protein 1 1 0 ENGEEGCHQNGLALPVVEEGEVLS(0.549)HS(0.451)LEAEHR 70.605 1.16E-05 2932600 886.03 499.93 814.15 609.04 636.63 899.92 470.07 479.43 852.94 706.6 TRUE FALSE FALSE 815.8997906 543.1417216 844.3231152 606.5199539 629.038603 713.2664478 483.2588991 625.606 759.374616 731.1542974 1.115906442 0.742855131 1.154781033 0.829537563 0.860336327 0.975534782 0.660953373 0.855641555 1.03859694 1 9.514032084 -5.894059135 0.623971121 1.047898096 0.774498202 0.27902261 0.129137761 0.7486409 0.511193326 0.026700124 0.1020245 1.28E-06 5.894059135 -0.273399894 ENIKPNET(ph)SPSFSK ddPTM_HeLa_Curcumin_4h_R1 1 ENIKPNETSPSFSK 14 1 H0YH87;A0A2R8Y7P6;A0A2R8YDM9;A0A5F9ZHH4;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A2R8Y5A6;A0A5F9ZHX3;A0A5F9ZHW5;Q99700-2;Q99700-5;Q99700-4;Q99700;F8W0B5;F8WB06 H0YH87;F8WB06 ATXN2 Ataxin-2 1 0 ENIKPNET(0.894)S(0.106)PS(0.001)FSK 167.92 1.26E-09 0 1812.7 1466.8 1634.5 1387.3 2048.4 2041.8 1451.8 1805.3 1350.3 1061.3 TRUE FALSE FALSE 1669.222882 1593.583656 1695.076008 1381.55972 2023.974168 1618.307664 1492.533601 2355.727659 1202.175468 1098.180096 1.519990108 1.451113221 1.543531898 1.258044764 1.843025725 1.47362684 1.359097298 2.14511961 1.094697921 1 10.10089895 -11.33837749 0.169595938 1.86E-13 1.759939295 0.505942709 0.2247247 16.69551514 0.367874606 6.5953515 0.421931908 4.59E-12 11.33837749 1.759939295 ENILEEFSK ddPTM_HeLa_Curcumin_4h_R1 1 ENILEEFSK 9 0 O43390;B4DT28;O43390-4;O43390-3;O43390-2 O43390 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 0 96.143 0.0082133 0 53.722 116.74 142.59 172.95 154.7 0 0 54.374 119.32 236.89 FALSE FALSE TRUE 49.46984701 126.8304854 147.8745108 172.2343787 152.8553035 0 0 70.95238229 106.2308945 245.1219099 0.20181732 0.517417988 0.60326925 0.702647833 0.623588906 0 0 0.289457529 0.433379842 1 7.937355633 -13.52287875 0.275448109 5.855634182 0.293513577 0.038164288 0.296741803 31.74622395 0.4274612 84.70813906 0.13154538 3.00E-14 13.52287875 -5.562120605 ENMT(ph)SQRGMLK ddPTM_HeLa_Curcumin_4h_R1 1 ENMTSQRGMLK 11 1 K7EJC8;E9PCW1;G5E9T8;O95249-2;O95249 K7EJC8 GOSR1 Golgi SNAP receptor complex member 1 1 0 ENMT(0.985)S(0.015)QRGMLK 61.213 0.0093591 0 3862.9 4768 4709.4 4103.5 3657.6 4372.6 4079.6 4428.6 5035.5 6469 TRUE FALSE FALSE 3557.147389 5180.124674 4883.934507 4086.520804 3613.985509 3465.673471 4194.062596 5778.859753 4483.118248 6693.797268 0.531409489 0.77386937 0.729620918 0.610493662 0.539900652 0.517744015 0.626559549 0.863315622 0.669742161 1 12.70860914 -9.411879956 0.99727303 1.012555887 0.636132216 0.036032124 0.146522068 0.32334366 0.543523854 0.091159503 0.020193798 3.87E-10 9.411879956 -0.376423671 ENPEDVLS(ph)PTSVATYLSSK ddPTM_HeLa_Curcumin_4h_R1 1 ENPEDVLSPTSVATYLSSK 19 0 Q5JTU8;B1AMJ5;A0A0A0MRG9;Q96SN8-4;Q96SN8-3;Q96SN8-2;Q96SN8 Q5JTU8 CDK5RAP2 CDK5 regulatory subunit-associated protein 2 1 0 ENPEDVLS(0.425)PT(0.258)S(0.258)VAT(0.054)YLS(0.003)S(0.001)K 83.948 0.003515 2589700 408 622.53 726.35 752.34 652.28 468.11 427.79 331.19 610.02 706.77 TRUE FALSE FALSE 375.7063695 676.3387193 753.26917 749.2270164 644.501987 371.0187093 439.7926361 432.1683064 543.1023322 731.3302049 0.513730141 0.924806216 1.029998713 1.024471588 0.881273579 0.507320369 0.601359869 0.590934579 0.742622592 1 9.514379138 -5.262078755 24.99136161 0.823232104 0.570020427 0.433352798 0.153565295 67.11571921 2623441.137 0.030895445 0.073234896 5.47E-06 5.262078755 -0.253211678 ENPPVEDS(ph)SDEDDKRNQGNLYDK ddPTM_HeLa_Curcumin_4h_R1 1 ENPPVEDSSDEDDKRNQGNLYDK 23 2 Q8TCJ2 Q8TCJ2 STT3B Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B 1 0 ENPPVEDS(0.453)S(0.453)DEDDKRNQGNLY(0.094)DK 66.282 0.001604 3964300 722.66 702.93 720.48 1104.6 947.86 1417.5 669.86 366.01 1304.8 1125.8 TRUE FALSE FALSE 665.4606985 763.688137 747.1816226 1100.029458 936.5573886 1123.494521 688.6544688 477.6047641 1161.666704 1164.921466 0.571249408 0.655570491 0.641400853 0.94429495 0.803966118 0.964437994 0.591159566 0.409988809 0.997206025 1 10.18601698 -9.475922286 1.21861178 0.999824836 0.697075613 0.357391531 0.160951635 0.470034048 1.249976495 0.118382953 0.029125659 3.34E-10 9.475922286 -0.302749224 ENPVLDVVS(ph)NPEQTAGEER ddPTM_HeLa_Curcumin_4h_R1 2 ENPVLDVVSNPEQTAGEER 19 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 ENPVLDVVS(1)NPEQTAGEER;ENPVLDVVS(1)NPEQTAGEER ; 184.6 1.49E-07 12499400 2915.15 2486.77 2571.02 2582.08 3407.5 3137.56 2444.36 1624.99 2451.08 2379.91 TRUE FALSE FALSE 2684.412801 2701.715318 2666.304263 2571.396037 3366.867788 2486.794688 2512.942163 2120.44197 2182.202656 2462.611695 1.09006743 1.097093514 1.082714042 1.044174379 1.367193941 1.009820059 1.020437842 0.86105413 0.886133474 1 11.26597345 -4.27582835 2.131848828 1.071262991 0.809767828 0.235599259 0.11496625 0.678511147 3.478512247 0.01446036 0.33414865 5.30E-05 4.27582835 -0.261495163 SQTPERPAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 SQTPERPAKK 10 2 A8CG34-2;A8CG34;C9JFL1;A6NF01;Q96HA1-2;Q96HA1-3;Q96HA1 A8CG34-2 POM121C;POM121B;POM121 Nuclear envelope pore membrane protein POM 121C;Putative nuclear envelope pore membrane protein POM 121B;Nuclear envelope pore membrane protein POM 121 0 1 ; SQTPERPAK(1)K;SQTPERPAK(1)K 94.82 0.0036165 3578500 2096.6 1868.51 1552.92 1924.56 1842.81 2510.5 2287.1 3971 2247.1 1867.57 FALSE TRUE FALSE 1930.651898 2030.015678 1610.472581 1916.596681 1820.835694 1989.794001 2351.269871 5181.73962 2000.598752 1932.467918 0.999060258 1.050478333 0.833376102 0.991787063 0.942233336 1.029664701 1.216718709 2.681410424 1.035255868 1 10.91622875 -4.240680062 2.891102947 0.989119874 3.025635621 0.986435596 0.059307703 0.033073826 0.371098093 0.008017423 0.160414417 5.75E-05 4.240680062 2.036515747 up LKPTNPAAQK(ac)ALTTPTHYK ddPTM_HeLa_Curcumin_4h_R1 2 LKPTNPAAQKALTTPTHYK 19 2 A0A3B3ITD8;P52948-6;P52948-2;P52948-5;P52948;P52948-4;P52948-3;H0YEN4;H0YCR0 A0A3B3ITD8 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 0 1 ; LKPTNPAAQK(1)ALTTPTHYK;LKPTNPAAQK(1)ALTTPTHYK 102.5 0.00049656 14166500 7118.9 5875.4 4995.5 5114.9 5517.3 8359 6752.8 10865.4 7145.9 5818.6 FALSE TRUE FALSE 6555.431553 6383.243396 5180.637624 5093.735899 5451.509801 6625.249175 6942.265394 14178.21044 6362.012648 6020.795917 1.088798166 1.060199263 0.860457271 0.846023677 0.905446701 1.100394245 1.153047785 2.354873116 1.056673027 1 12.5557385 -4.237266359 3.071580606 1.011634691 2.608858333 0.953359678 0.089896511 0.069226637 0.92352922 0.014291422 0.274861523 5.79E-05 4.237266359 1.597223641 up ENPVVVGEK(ac)IQKI ddPTM_HeLa_Curcumin_4h_R1 1 ENPVVVGEKIQKI 13 2 Q6FIF0-2;Q6FIF0 Q6FIF0-2 ZFAND6 AN1-type zinc finger protein 6 0 1 ENPVVVGEK(1)IQKI 168.82 3.33E-05 1304700 808.9 717.91 930.31 731.9 655.83 1608 910.22 1380.9 1235.2 781.55 FALSE TRUE FALSE 744.8747115 779.9629415 964.788107 728.8715917 648.0096556 1274.482674 935.7583235 1801.930053 1099.70165 808.7088043 0.921066653 0.964454619 1.192998149 0.901278171 0.801289231 1.575947569 1.157101689 2.228156839 1.359824011 1 9.659476508 -1.170458217 0.782895555 0.969904838 199.999999 0.684403114 0.2279418 96.98691941 0.462866134 0.027632688 34027.15969 0.067537003 1.170458217 199.0300942 ENPVYEK ddPTM_HeLa_Curcumin_4h_R1 2 ENPVYEK 7 0 P46777;A0A2R8Y6J3;A0A2R8Y4A2 P46777 RPL5 60S ribosomal protein L5 0 0 ; ; 110.31 0.013693 24811000 8270.1 7202.5 7547.3 8009.8 7497.1 8941 6826 6635.9 8835.4 7757.1 FALSE FALSE TRUE 7615.512858 7825.052006 7827.009577 7976.65757 7407.701979 7086.535814 7017.519189 8659.155362 7866.178725 8026.658648 0.948777467 0.974882868 0.975126752 0.993770624 0.922887381 0.882874945 0.87427652 1.078799503 0.980006634 1 12.97058383 -5.754077685 24.99012239 0.976236349 0.930976173 0.102347384 0.053934383 258.2610857 876689.0548 0.007592348 0.014940417 1.76E-06 5.754077685 -0.045260177 ENPYYDSR ddPTM_HeLa_Curcumin_4h_R1 2 ENPYYDSR 8 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 ; ; 127.46 0.0019175 11118400 6155.3 5451.9 5612.3 5602.4 6282.8 6075 4951.8 4322.8 6121.1 5950.5 FALSE FALSE TRUE 5668.10151 5923.137943 5820.296775 5579.218753 6207.881713 4814.976521 5090.734181 5640.80182 5449.630644 6157.279432 0.920552912 0.961973223 0.945270852 0.906117517 1.008218286 0.781997402 0.826783036 0.916119186 0.885071192 1 12.58807733 -1 0.098959849 1.045765038 0.484251435 0.10101001 0.063967273 99.17001458 0.701037223 0.471062271 7.59464383 0.1 1 -0.561513603 T(ph)QSLPVTEK ddPTM_HeLa_Curcumin_4h_R1 1 TQSLPVTEK 9 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 0 T(0.687)QS(0.108)LPVT(0.205)EK 128.88 0.011871 64853000 6707.3 4281 5693.8 6492.8 4725 5284 6767.3 13555 4583 4790.8 TRUE FALSE FALSE 6176.410127 4651.030564 5904.817237 6465.934514 4668.657461 4188.038837 6957.172225 17687.8571 4080.256366 4957.279943 1.245927242 0.938222295 1.191140566 1.304331123 0.941778055 0.84482597 1.403425327 3.568056939 0.82308371 1 12.27533302 -4.266701319 3.665659098 1.097508202 3.826243632 0.953699744 0.165930569 0.035211804 0.869975435 0.021069997 0.259243995 5.41E-05 4.266701319 2.72873543 up ENQEPLRS(ph)LEDENKEAFR ddPTM_HeLa_Curcumin_4h_R1 1 ENQEPLRSLEDENKEAFR 18 2 P48681 P48681 NES Nestin 1 0 ENQEPLRS(1)LEDENKEAFR 61.139 0.019282 3801400 1231.6 1027.4 1075.2 976.05 1124.3 1182.4 1147.5 1206.6 1228.7 1045.2 TRUE FALSE FALSE 1134.11756 1116.203878 1115.047858 972.0113637 1110.893457 937.1569116 1179.695762 1574.486785 1093.914684 1081.520622 1.048632395 1.032068973 1.031000089 0.898745104 1.02715883 0.866517838 1.090775097 1.455808381 1.011459848 1 10.07884546 -4.291328314 3.657833806 1.006978996 1.49214848 0.843109115 0.059800453 0.068459295 1.6662687 0.008209712 0.08560742 5.11E-05 4.291328314 0.485169484 RDS(ph)GDNSAPSGQER ddPTM_HeLa_Curcumin_4h_R1 1 RDSGDNSAPSGQER 14 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 0 RDS(1)GDNSAPSGQER 94.61 0.0035924 6559000 1233.4 1141.3 1177.1 1388.1 1363.6 1422.5 1428.5 1876.1 950.38 1159.6 TRUE FALSE FALSE 1135.775089 1239.948886 1220.724361 1382.35641 1347.339961 1127.457465 1468.579865 2448.114253 846.1256917 1199.896014 0.946561265 1.033380287 1.017358461 1.152063507 1.122880604 0.939629311 1.223922614 2.040272012 0.705165849 1 10.22869367 -4.266047429 2.616280003 1.002893114 2.248364937 0.879605613 0.116423812 0.075953865 0.671495502 0.010789926 0.205576816 5.42E-05 4.266047429 1.245471823 up ENQPENSQT(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 2 ENQPENSQTPTK 12 0 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 0 ENQPENS(0.001)QT(0.994)PT(0.005)K;ENQPENSQT(0.915)PT(0.085)K ; 212.03 1.90E-09 31071000 9187.5 7279.3 7985.7 7991.3 8850.2 10021.3 7812.4 2924.7 9023.7 7432.1 TRUE FALSE FALSE 8460.29968 7908.490256 8281.657067 7958.234118 8744.667145 7942.769417 8031.594918 3816.427566 8033.822686 7690.364922 1.100116804 1.028363457 1.076887398 1.034831793 1.137093914 1.032820874 1.044371106 0.496260919 1.044660789 1 12.90883634 -4.261243854 6.736741857 1.053248514 0.486573795 0.952389778 0.037510906 0.019757016 5.991835778 0.006125154 0.05067196 5.48E-05 4.261243854 -0.566674719 ENQPENSQT(ph)PTKK ddPTM_HeLa_Curcumin_4h_R1 4 ENQPENSQTPTKK 13 1 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 0 ENQPENSQT(0.73)PT(0.27)KK;ENQPENSQT(0.98)PT(0.02)KK;ENQPENS(0.001)QT(0.981)PT(0.018)KK;ENQPENS(0.186)QT(0.707)PT(0.107)KK ;;; 256.35 3.46E-35 462542200 14819.7 13113 12635.9 11812.6 12245.6 16662 12781.3 4968.35 15384 12010.9 TRUE FALSE FALSE 13646.70511 14246.42929 13104.19757 11763.72259 12099.57922 13206.11338 13139.90888 6483.177044 13696.41369 12428.27788 1.09803669 1.1462915 1.054385627 0.946528771 0.973552356 1.062585944 1.057259019 0.521647255 1.102036326 1 13.60133878 -4.260590247 24.97292011 1.044496909 0.521647089 0.881126305 0.058084565 18.54862627 545419.6044 0.008765238 0.071137628 5.49E-05 4.260590247 -0.52284982 ENQSEGKGS(ph)DSDSEGDNPEK ddPTM_HeLa_Curcumin_4h_R1 1 ENQSEGKGSDSDSEGDNPEK 20 1 I3L4J1;Q9UN37 I3L4J1 VPS4A Vacuolar protein sorting-associated protein 4A 1 0 ENQSEGKGS(0.77)DS(0.2)DS(0.029)EGDNPEK 97.049 0.00031881 50447000 4790.2 4002.5 4782.9 4358.8 5170 5122.4 4667.2 4003.4 4127.2 3707.8 TRUE FALSE FALSE 4411.050615 4348.458265 4960.158481 4340.764441 5108.351127 4059.956499 4798.149071 5224.018231 3674.456486 3836.645774 1.14971537 1.133401028 1.292837226 1.131395676 1.3314628 1.058204676 1.250610391 1.361610776 0.95772628 1 11.90562986 -13.52287869 0.086314086 0.231035227 1.422734915 0.579020016 0.085577263 85.03246172 0.558703813 12.10057029 1.137765018 3.00E-14 13.52287869 1.191699688 ENQSEGKGS(ph)DSDSEGDNPEKK ddPTM_HeLa_Curcumin_4h_R1 1 ENQSEGKGSDSDSEGDNPEKK 21 2 I3L4J1;Q9UN37 I3L4J1 VPS4A Vacuolar protein sorting-associated protein 4A 1 0 ENQS(0.008)EGKGS(0.567)DS(0.111)DS(0.314)EGDNPEKK 64.249 0.0018915 17425000 4521.7 3618 4264.3 4011.6 4331.6 5077.5 3416.1 3622.5 4432.6 3500.2 TRUE FALSE FALSE 4163.802674 3930.723799 4422.338709 3995.001062 4279.948499 4024.369265 3511.946572 4726.983574 3946.35487 3621.831689 1.149640025 1.085286158 1.2210227 1.103033328 1.181708281 1.111141988 0.969660347 1.30513618 1.08960195 1 11.82250379 -9.261409317 0.760920349 0.990033281 1.136706817 0.126958826 0.087968791 0.797873752 0.740652556 0.073501229 0.015520512 5.48E-10 9.261409317 0.146673536 ENQSEGKGSDS(ph)DSEGDNPEK ddPTM_HeLa_Curcumin_4h_R1 1 ENQSEGKGSDSDSEGDNPEK 20 1 I3L4J1;Q9UN37 I3L4J1 VPS4A Vacuolar protein sorting-associated protein 4A 1 0 ENQSEGKGS(0.006)DS(0.863)DS(0.131)EGDNPEK 96.379 0.00033578 47846000 2289.2 1922.4 2192 2001.7 2513.7 2355.2 1702.8 2079.5 1898.3 1628.3 TRUE FALSE FALSE 2108.007404 2088.56369 2273.237448 1993.417496 2483.725769 1866.704971 1750.575985 2713.529977 1690.061239 1684.883304 1.251129618 1.239589522 1.349195783 1.183119027 1.47412332 1.107913508 1.038989455 1.610515085 1.003073172 1 10.71843296 -9.063813753 0.555597632 0.964814116 1.280356174 0.335511248 0.158262852 1.096819845 0.532989573 0.177381586 0.037372582 8.63E-10 9.063813753 0.315542057 ENS(ph)PAVS(ph)PTTNSTAPFGLKPR ddPTM_HeLa_Curcumin_4h_R1 1 ENSPAVSPTTNSTAPFGLKPR 21 1 Q9Y2L9-2;Q9Y2L9;Q9Y2L9-3 Q9Y2L9-2 LRCH1 Leucine-rich repeat and calponin homology domain-containing protein 1 2 0 ENS(0.827)PAVS(0.989)PT(0.171)T(0.012)NS(0.001)TAPFGLKPR 86.604 0.00053492 9917000 3049.5 2415.1 2789.5 2598.3 2977.6 3502.1 3034.9 2783.3 3049.2 2823.6 TRUE FALSE FALSE 2808.128857 2623.850483 2892.881324 2587.548923 2942.094065 2775.724983 3120.051126 3631.915357 2714.710389 2921.71989 0.961121861 0.898049978 0.990129592 0.885625255 1.00697335 0.950031176 1.067881674 1.243074454 0.929148067 1 11.51260216 -4.345443635 2.219898691 0.968973494 1.287281813 0.818755209 0.041686852 0.157492489 1.009904201 0.005683381 0.091140329 4.51E-05 4.345443635 0.318308319 ENS(ph)PNSFPR ddPTM_HeLa_Curcumin_4h_R1 1 ENSPNSFPR 9 0 A0A075B785;A0A2R8Y566;Q9P260;Q9P260-2 A0A075B785 KIAA1468 LisH domain and HEAT repeat-containing protein KIAA1468 1 0 ENS(0.999)PNS(0.001)FPR 89.805 0.01969 20806000 2860.5 2917.9 3011.1 3014.4 2972 2620.5 2086 1521.8 2582.7 2502.4 TRUE FALSE FALSE 2634.088407 3170.110274 3122.694015 3001.927212 2936.560841 2076.978761 2144.527546 1985.789814 2299.384272 2589.358214 1.017274625 1.224284171 1.205972197 1.159332531 1.134088295 0.802121062 0.828208138 0.766904248 0.888013199 1 11.33837885 -5.250611865 24.15433648 1.059068533 0.801990801 0.62859869 0.100484785 267.3205464 596343.6356 0.015083416 0.038007171 5.62E-06 5.250611865 -0.257077732 ENS(ph)S(ph)AGT(ph)LPSDLGAS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 ENSSAGTLPSDLGASK 16 0 Q14CZ8-2 Q14CZ8-2 4 0 ENS(0.994)S(0.747)AGT(0.629)LPS(0.629)DLGAS(1)K 58.676 0.0096232 0 1063.1 714.58 1033 827.39 492.26 422.25 426.67 677.27 936.28 770.37 TRUE FALSE FALSE 978.9545132 776.3451111 1071.283889 823.9664794 486.390121 334.6705903 438.6412119 883.7665052 833.5724265 797.1403002 1.228083078 0.973912762 1.343908831 1.033653021 0.610168776 0.419839005 0.550268518 1.108671215 1.045703531 1 9.638689857 -5.820402936 5.048413437 1.116723421 0.644955736 0.540593124 0.195246207 0.11033905 5.670490691 0.02884484 0.053879604 1.51E-06 5.820402936 -0.471767685 ENS(ph)S(ph)S(ph)KS(ph)KK ddPTM_HeLa_Curcumin_4h_R1 1 ENSSSKSKK 9 2 O15014;E7ERY8;O15014-2 O15014 ZNF609 Zinc finger protein 609 4 0 ENS(1)S(1)S(1)KS(1)KK 49.813 0.0093326 0 221.36 362.43 431.22 349.16 474.3 430.96 359.52 279.23 281.71 369.8 TRUE FALSE FALSE 203.8391224 393.7568342 447.2013925 347.7152684 468.6442823 341.5740381 369.6071636 364.3659416 250.8071178 382.6505225 0.532703108 1.029024687 1.16869406 0.90870193 1.22473185 0.892652742 0.965913129 0.952215978 0.65544695 1 8.579883559 -7.174048427 24.9973509 0.779329526 1.022558359 0.430491452 0.150044709 76.10314295 21766.91604 0.03217996 0.039412241 6.70E-08 7.174048427 0.243228833 ENSFGS(ph)PLEFR ddPTM_HeLa_Curcumin_4h_R1 2 ENSFGSPLEFR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 ENS(0.012)FGS(0.988)PLEFR;ENS(0.001)FGS(0.999)PLEFR ; 150.9 0.00056738 131520200 4769.2 4539.1 4579.5 4283.9 5171.6 4920.5 3941.8 5022.5 4497.3 3583.2 TRUE FALSE FALSE 4391.712788 4931.439578 4749.220299 4266.174357 5109.932048 3899.932835 4052.396299 6553.837129 4003.957442 3707.715933 1.184479304 1.330047843 1.280901877 1.150620607 1.378188658 1.051842402 1.092962992 1.767621157 1.079898653 1 11.856315 -8.125962991 0.039962069 1.29E-13 2.280459352 0.269183032 0.182930467 93.64030249 1.996099114 60.49783823 52.71242804 7.48E-09 8.125962991 2.280459352 ENSLCGS(ph)APNSR ddPTM_HeLa_Curcumin_4h_R1 1 ENSLCGSAPNSR 12 0 Q2NKX8;B5MDQ0 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 0 ENSLCGS(0.903)APNS(0.096)R 97.823 0.010517 6821600 1775.1 1511 1832.4 1513.1 1291.6 1326.2 915.44 541.95 1282.4 1359.8 TRUE FALSE FALSE 1634.598962 1641.604107 1900.310356 1506.839193 1276.198514 1051.131171 941.1247826 707.1880602 1141.723928 1407.052949 1.161718159 1.166696753 1.350560658 1.070918614 0.907001058 0.747044503 0.668862379 0.502602308 0.811429257 1 10.4584609 -5.231084769 1.422445545 1.1080714 0.565434599 0.705171782 0.1340532 0.157079443 0.581479361 0.01758441 0.071319094 5.87E-06 5.231084769 -0.542636801 ENTEFTDHELQEWYK ddPTM_HeLa_Curcumin_4h_R1 2 ENTEFTDHELQEWYK 15 0 E9PC71;P37235 E9PC71 HPCAL1 Hippocalcin-like protein 1 0 0 ; ; 140.49 0.0004274 10979200 8226.4 6690 7344 7353.9 8387.6 8167.9 5812.4 5198.5 6680.9 5925.4 FALSE FALSE TRUE 7575.27176 7268.25379 7616.1751 7323.47151 8287.583348 6473.785469 5975.480301 6783.498719 5948.021985 6131.307209 1.235506802 1.185432982 1.242178028 1.194438847 1.351682939 1.055857299 0.974585043 1.106370711 0.970106664 1 12.58197898 -5.025967207 24.84096319 1.151665017 1.034163616 0.195143483 0.110873026 929.771531 889447.0375 0.017395972 0.044536453 9.42E-06 5.025967207 -0.1175014 ENTQTTIK ddPTM_HeLa_Curcumin_4h_R1 2 ENTQTTIK 8 0 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 0 ; ; 138.1 0.00087845 5757900 1443.2 1915.64 849.47 712.05 1026.73 1577.22 920.42 989.5 1074.57 1314.08 FALSE FALSE TRUE 1328.969197 2081.219386 880.9521055 709.1037258 1014.486915 1250.086793 946.244508 1291.193995 956.6923594 1359.744182 0.977367077 1.530596279 0.647880768 0.521497893 0.746086601 0.919354397 0.69589892 0.949585968 0.703582609 1 10.40911954 ENVEYIEREES(ph)DGEYDEFGR ddPTM_HeLa_Curcumin_4h_R1 6 ENVEYIEREESDGEYDEFGR 20 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 ENVEY(0.01)IEREES(0.982)DGEY(0.008)DEFGR;ENVEY(0.001)IEREES(0.997)DGEY(0.002)DEFGR;ENVEYIEREES(0.998)DGEY(0.002)DEFGR;ENVEYIEREES(0.997)DGEY(0.002)DEFGR;ENVEYIEREES(0.996)DGEY(0.004)DEFGR;ENVEY(0.077)IEREES(0.916)DGEY(0.007)DEFGR ;;;;; 96.777 0.00032572 2239722000 8289.46 7132.87 7437.99 7761.5 8042.98 9295.6 7609.26 6895.32 8661.2 7257.98 TRUE FALSE FALSE 7633.340494 7749.403499 7713.648453 7729.38497 7947.072717 7367.587777 7822.755356 8997.671326 7711.088029 7510.194265 1.01639721 1.031851271 1.027090403 1.029185757 1.058171392 0.981011611 1.041618243 1.198061063 1.026749476 1 12.87463451 -4.274839554 3.630223083 1.014578279 1.216146472 0.869358104 0.020275745 0.062874769 1.509114058 0.002863254 0.033540957 5.31E-05 4.274839554 0.201568193 ENVEYIEREESDGEY(ph)DEFGRK ddPTM_HeLa_Curcumin_4h_R1 1 ENVEYIEREESDGEYDEFGRK 21 2 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 ENVEY(0.005)IEREES(0.232)DGEY(0.762)DEFGRK 47.688 0.016145 25477000 2485.8 2022.1 1929.1 2294.5 2418.9 2741.2 2030.6 2013.8 2515 2287.5 TRUE FALSE FALSE 2289.046307 2196.881314 2000.594143 2285.005967 2390.056197 2172.64422 2087.573171 2627.79835 2239.110792 2366.990455 0.967070358 0.92813273 0.845205835 0.965363406 1.009744755 0.917893106 0.881952509 1.110185444 0.945973731 1 11.20883817 -8.035315488 1.392356551 0.991748147 0.947240273 0 0.070097292 0.739284083 2.95544882 0.015793961 0.013291585 9.22E-09 8.035315488 -0.044507874 EPAITSQNS(ph)PEAR ddPTM_HeLa_Curcumin_4h_R1 2 EPAITSQNSPEAR 13 0 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193;E5RIS7 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 1 0 EPAITSQNS(1)PEAR;EPAITSQNS(1)PEAR ; 205.28 5.70E-09 356890000 4173.1 3348.3 4171.7 3843 3921.2 4359.1 3572 2916.2 3758 3358.24 TRUE FALSE FALSE 3842.794732 3637.712132 4326.306872 3827.098684 3874.442251 3454.973523 3672.220706 3805.335955 3345.756802 3474.93859 1.105859753 1.046842135 1.245002396 1.101342825 1.114967114 0.994254555 1.056772835 1.095080059 0.962824728 1 11.76277177 -9.208155821 0.886147733 0.998450485 1.095045036 0.333922089 0.062330397 0.712337257 0.980796675 0.04537241 0.01191853 6.19E-10 9.208155821 0.096594551 EPAITSQNS(ph)PEAREESTSSGNVSNR ddPTM_HeLa_Curcumin_4h_R1 2 EPAITSQNSPEAREESTSSGNVSNR 25 1 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 1 0 EPAIT(0.003)S(0.01)QNS(0.959)PEAREES(0.013)T(0.013)S(0.001)S(0.001)GNVSNR;EPAIT(0.039)S(0.19)QNS(0.742)PEAREES(0.006)T(0.006)S(0.008)S(0.008)GNVSNR ; 84.025 4.61E-05 32502000 1147.9 954.56 1013.7 1132.58 929.43 1286.39 1049.38 799.29 1593.95 1456.34 TRUE FALSE FALSE 1057.042504 1037.067913 1051.268614 1127.893684 918.3471543 1019.578213 1078.822779 1042.989842 1419.097673 1506.947707 0.701446042 0.688191042 0.697614528 0.748462391 0.609408774 0.676585 0.71589928 0.692120793 0.94170333 1 10.55741364 -9.156112345 0.575757971 1.04350012 0.682839367 0.899378411 0.037231413 0.221833563 0.11127671 0.042403288 0.008159544 6.98E-10 9.156112345 -0.360660753 S(ph)ESVEGFLSPSR ddPTM_HeLa_Curcumin_4h_R1 4 SESVEGFLSPSR 12 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 0 S(0.976)ES(0.024)VEGFLSPSR;S(0.996)ES(0.004)VEGFLSPSR;S(0.945)ES(0.055)VEGFLSPSR;S(0.965)ES(0.035)VEGFLSPSR ;;; 188.96 6.46E-06 59288000 6962 5460.6 5030.73 5461.5 5501.69 7360.7 7473 9799.7 7251.3 5464.53 TRUE FALSE FALSE 6410.950354 5932.589932 5217.173279 5438.90176 5436.08594 5834.007848 7682.672267 12787.58342 6455.850532 5654.422011 1.133794107 1.049194758 0.922671366 0.961884654 0.961386669 1.031760247 1.358701606 2.261519107 1.141734826 1 12.46516385 -4.26577752 2.213341976 1.036793119 2.57531924 0.966377095 0.069539655 0.08811623 0.49033298 0.011324137 0.264152581 5.42E-05 4.26577752 1.53852612 up S(ph)ASDSGCDPASK ddPTM_HeLa_Curcumin_4h_R1 2 SASDSGCDPASK 12 0 Q7LBC6;H0Y9V5 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 0 S(0.854)AS(0.06)DS(0.086)GCDPASK;S(1)ASDSGCDPASK ; 135.04 0.001822 38592000 6012.4 5951.6 5954.9 4928.6 5432.6 6371.5 6622.9 10753.6 5580.2 6089 TRUE FALSE FALSE 5536.512196 6466.029784 6175.593832 4908.206759 5367.819793 5049.979078 6808.720749 14032.32314 4968.066021 6300.592297 0.878728846 1.02625745 0.980160839 0.779007199 0.851954791 0.801508627 1.080647728 2.227143493 0.788507776 1 12.62127174 -4.265754918 3.689668506 0.924521177 2.362535627 0.950700669 0.090625052 0.03864822 0.975160832 0.0122623 0.150827534 5.42E-05 4.265754918 1.43801445 up EPAPLLSAQYETLS(ph)DSDD ddPTM_HeLa_Curcumin_4h_R1 2 EPAPLLSAQYETLSDSDD 18 0 A0A088AWL3;O75376-2;O75376;E7EVK1 A0A088AWL3 NCOR1 Nuclear receptor corepressor 1 1 0 EPAPLLSAQYETLS(0.5)DS(0.5)DD;EPAPLLSAQYETLS(0.5)DS(0.5)DD ; 126.16 0.0002257 10080700 5471.5 4174.2 4365.6 4358 4636 5606.9 3253.4 1724.64 4338.7 4026.5 TRUE FALSE FALSE 5038.425001 4534.999248 4527.392976 4339.967751 4580.718728 4443.965737 3344.681648 2250.474797 3862.755465 4166.420575 1.209293424 1.088464106 1.086638493 1.041653782 1.09943743 1.066614773 0.802771009 0.540145853 0.927116069 1 12.02459276 -4.486018886 1.875514776 1.096034446 0.482716613 0.833274762 0.074059474 0.147399826 0.737624906 0.011172773 0.134245329 3.27E-05 4.486018886 -0.613317833 EPDATPPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 EPDATPPSPR 10 0 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 0 EPDATPPS(1)PR;EPDATPPS(1)PR ; 118.77 0.0047802 26357000 3856.7 4148.8 3950.2 3974.5 4610.4 4371.3 4132.3 3015.1 3903.5 3388.6 TRUE FALSE FALSE 3551.438125 4507.403785 4096.597887 3958.054572 4555.423991 3464.643105 4248.241216 3934.39011 3475.295816 3506.353598 1.012857952 1.285496074 1.168335643 1.128823566 1.299191272 0.988104311 1.2115838 1.122074543 0.991142427 1 11.77575578 -7.358821625 9.056583994 1.005770054 1.169416574 0.468956675 0.083144842 0.220526946 19.01967746 0.013022634 0.014871301 4.38E-08 7.358821625 0.16364652 EPEAAS(ph)SRGSPVR ddPTM_HeLa_Curcumin_4h_R1 1 EPEAASSRGSPVR 13 1 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 0 EPEAAS(0.803)S(0.162)RGS(0.035)PVR 74.783 0.012607 23920000 3550.9 2361.5 3609.9 3535.5 3247.7 4039 3361.2 2315.6 2854.9 3000.4 TRUE FALSE FALSE 3269.842518 2565.617537 3743.68607 3520.871038 3208.973299 3201.265871 3455.506226 3021.61578 2541.724613 3104.663677 1.053203457 0.826375352 1.205826608 1.134058759 1.03359772 1.031115188 1.11300501 0.973250598 0.818679534 1 11.60022128 EPEAASSRGS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 1 EPEAASSRGSPVR 13 1 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 0 EPEAAS(0.011)S(0.047)RGS(0.942)PVR 65.528 0.018505 154310000 2951.2 2716.8 2716.4 2957.8 2574 3388.5 2836.7 1460.6 3071.5 2744 TRUE FALSE FALSE 2717.609406 2951.628086 2817.072174 2945.561407 2543.306731 2685.686904 2916.290167 1905.930216 2734.564135 2839.353796 0.957122501 1.039542198 0.992152573 1.037405557 0.895734352 0.945879625 1.027096437 0.671254924 0.963093834 1 11.47134691 -4.25641597 24.92136622 0.982539194 0.671254789 0.826150392 0.043064424 149.2145094 740234.5069 0.005787721 0.064448769 5.54E-05 4.25641597 -0.311284404 EPEDEEEEEEEEEEDEDEDLEELEVLER ddPTM_HeLa_Curcumin_4h_R1 1 EPEDEEEEEEEEEEDEDEDLEELEVLER 28 0 Q9NQC3-5;Q9NQC3;Q9NQC3-2;Q9NQC3-4;F8W914 Q9NQC3-5 RTN4 Reticulon-4;Reticulon 0 0 144.73 4.35E-10 7590400 1863.2 1353.7 1803.6 2246.1 1660.4 2250.4 2249.8 1582.5 1981.5 1670 FALSE FALSE TRUE 1715.725754 1470.707796 1870.443003 2236.806233 1640.600814 1783.641673 2312.923333 2064.996965 1764.134407 1728.032376 0.992878246 0.851088103 1.082412013 1.294423799 0.94940398 1.032180703 1.338472222 1.194999002 1.020891988 1 10.75491453 -6.527738103 24.99210897 0.984727916 1.156266597 0.388795024 0.114648619 115.7049843 595078.7919 0.017886712 0.025347692 2.97E-07 6.527738103 0.17153868 EPEDEGEDDD ddPTM_HeLa_Curcumin_4h_R1 2 EPEDEGEDDD 10 0 P39687 P39687 ANP32A Acidic leucine-rich nuclear phosphoprotein 32 family member A 0 0 ; ; 161.9 0.0051449 51436000 15067.8 13842.1 14733.9 13419.2 16168.6 16535.4 13841.9 12812.8 13993.1 13672.3 FALSE FALSE TRUE 13875.16773 15038.54944 15279.9513 13363.67491 15975.80001 13105.77165 14230.26646 16719.36374 12458.09194 14147.41141 0.980756644 1.062989476 1.080052799 0.944602127 1.129238385 0.926372413 1.005856552 1.181796673 0.880591621 1 13.78825048 -7.26962815 24.1796817 0.990912859 1.041494137 0.17572424 0.080994004 673.8975496 1989872.323 0.011575648 0.013371706 5.37E-08 7.26962815 0.050581278 EPEPAAGPQAEESATVSAPAPMS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 2 EPEPAAGPQAEESATVSAPAPMSPTR 26 0 Q9BWG6-2;Q9BWG6 Q9BWG6-2 SCNM1 Sodium channel modifier 1 1 0 EPEPAAGPQAEESATVS(0.005)APAPMS(0.803)PT(0.191)R;EPEPAAGPQAEES(0.001)AT(0.003)VS(0.022)APAPMS(0.729)PT(0.244)R ; 108.44 9.79E-08 16172300 5643.4 4815.6 5057.5 5241.6 6102 7086 5460.1 4324.4 4887.2 4430.9 TRUE FALSE FALSE 5196.718935 5231.839006 5244.935399 5219.911648 6029.237635 5616.283724 5613.295711 5642.889653 4351.086387 4584.873445 1.133448719 1.141108706 1.143965141 1.138507248 1.315028148 1.224959378 1.224307667 1.230762358 0.949009049 1 12.1626662 -8.045996565 0.202369531 0.91134351 1.301173401 0.826552405 0.043344172 1.097329248 0.154107359 0.15849458 0.095440958 9.00E-09 8.045996565 0.389829891 EPEPAAGPQAEESATVSAPAPMS(ph)PTRR ddPTM_HeLa_Curcumin_4h_R1 2 EPEPAAGPQAEESATVSAPAPMSPTRR 27 1 Q9BWG6-2;Q9BWG6 Q9BWG6-2 SCNM1 Sodium channel modifier 1 1 0 EPEPAAGPQAEESATVSAPAPMS(0.885)PT(0.115)RR;EPEPAAGPQAEES(0.006)AT(0.021)VS(0.018)APAPMS(0.675)PT(0.28)RR ; 141.92 1.88E-08 10318900 2485.8 1978.11 2333.3 1971.56 2339.1 2961.7 2422.7 1816.02 1962.15 1927.69 TRUE FALSE FALSE 2289.046307 2149.089014 2419.774151 1963.402207 2311.20776 2347.410035 2490.674442 2369.716138 1746.907054 1994.677084 1.147577382 1.077411994 1.213115732 0.984320832 1.158687679 1.17683712 1.248660478 1.188019934 0.87578439 1 10.96193949 -13.52287875 0.090449136 0.500454892 1.287439297 0.526761158 0.077806286 95.96033254 0.656954386 9.421257848 0.79661291 3.00E-14 13.52287875 0.786984405 EPES(ph)PPASAPIPLFGADTIGQR ddPTM_HeLa_Curcumin_4h_R1 2 EPESPPASAPIPLFGADTIGQR 22 0 Q96AY4 Q96AY4 TTC28 Tetratricopeptide repeat protein 28 1 0 EPES(1)PPASAPIPLFGADTIGQR;EPES(1)PPASAPIPLFGADTIGQR ; 204.17 1.58E-17 22178500 5505.7 4387.2 4866.4 4965.3 5499.5 5932.9 4377.9 4966 5062.2 4557.3 TRUE FALSE FALSE 5069.918035 4766.410019 5046.753065 4944.754904 5433.922054 4702.349662 4500.732091 6480.110539 4506.889325 4715.665836 1.075122414 1.010760767 1.07021007 1.048580429 1.15231279 0.997176184 0.954421337 1.374166611 0.955727035 1 12.20324577 -4.252485369 24.96570212 1.038860473 1.374166787 0.761037674 0.057742608 402.5130708 1122269.064 0.007330775 0.119104997 5.59E-05 4.252485369 0.335306313 EPFPPS(ph)SPLQK ddPTM_HeLa_Curcumin_4h_R1 1 EPFPPSSPLQK 11 0 E7EPJ7;O75962-5;O75962-4;O75962 E7EPJ7 TRIO Triple functional domain protein 1 0 EPFPPS(0.5)S(0.5)PLQK 128.67 0.0030433 5256600 1784.7 1498.1 1704.1 1569 2163.5 2545.4 2162.3 1875.1 1837.1 1680 TRUE FALSE FALSE 1643.439112 1627.589089 1767.255445 1562.507894 2137.701676 2017.455347 2222.968318 2446.809358 1635.574726 1738.379875 0.945385491 0.936267793 1.016610622 0.898829949 1.229709171 1.16053768 1.278758659 1.407522828 0.940861517 1 10.76352766 -5.07095085 0.894766446 0.967808915 1.414725742 0.843341928 0.065878467 0.241558373 0.277053784 0.010191415 0.080099829 8.49E-06 5.07095085 0.446916827 EPFPPSS(ph)PLQK ddPTM_HeLa_Curcumin_4h_R1 2 EPFPPSSPLQK 11 0 E7EPJ7;O75962-5;O75962-4;O75962 E7EPJ7 TRIO Triple functional domain protein 1 0 EPFPPS(0.084)S(0.916)PLQK;EPFPPS(0.422)S(0.578)PLQK ; 150.51 0.00059673 20452600 6388.6 5795.7 5675.2 5781.4 6758.6 7094.6 8054.6 5460.8 5661.7 5627.4 TRUE FALSE FALSE 5882.935569 6296.654483 5885.527904 5757.478099 6678.008109 5623.099987 8280.590398 7125.772782 5040.625675 5822.951731 1.010301277 1.081350967 1.01074647 0.988755938 1.146842429 0.965678619 1.422060628 1.22373894 0.865647855 1 12.50753494 -4.76684544 24.99966263 1.017736455 1.322899812 0.699834747 0.082146549 35.25492851 163035.7395 0.008352761 0.026158967 1.71E-05 4.76684544 0.305163357 EPGEQASVPLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 EPGEQASVPLSPK 13 0 P42858 P42858 HTT Huntingtin 1 0 EPGEQASVPLS(1)PK 178.22 0.0001835 33327000 3364.7 3216.7 3124.5 3182.6 3501 2898.5 2572.6 1650.4 2994.3 3225.3 TRUE FALSE FALSE 3098.380445 3494.737215 3240.296719 3169.431244 3459.252862 2297.318427 2644.780232 2153.599362 2665.832781 3337.378935 0.928387368 1.047150259 0.97091064 0.949676769 1.036517857 0.688360079 0.792472262 0.645296625 0.79878037 1 11.70449979 -5.256972595 24.99991606 0.974836095 0.7170859 0.706807815 0.074250045 100.0717121 560083.6613 0.006926135 0.017012728 5.53E-06 5.256972595 -0.257750194 EPGFEAGPEAS(ph)DDDLWTR ddPTM_HeLa_Curcumin_4h_R1 2 EPGFEAGPEASDDDLWTR 18 0 H9KVB4;O15417-2;O15417;H7C177 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 0 EPGFEAGPEAS(1)DDDLWTR;EPGFEAGPEAS(1)DDDLWTR ; 231.38 9.91E-24 14625100 1208.64 1118.96 849.15 1093.31 1320.19 1300.27 1183.6 526.99 965.8 1114.3 TRUE FALSE FALSE 1112.974869 1215.677916 880.620246 1088.786173 1304.447596 1030.579345 1216.808631 687.666825 859.8541563 1153.021842 0.96526781 1.054340752 0.763749839 0.944289287 1.131329476 0.893807305 1.055321405 0.596403988 0.745739695 1 10.17120413 -4.254302125 24.93306767 0.978180858 0.596403804 0.423480582 0.120052246 408.9065993 1428425.189 0.012061848 0.163135187 5.57E-05 4.254302125 -0.381777054 EPGGRS(ph)PAFVQLAPLSSK ddPTM_HeLa_Curcumin_4h_R1 2 EPGGRSPAFVQLAPLSSK 18 1 P51610-2;P51610;A6NEM2;P51610-4 P51610-2 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 0 EPGGRS(1)PAFVQLAPLSSK;EPGGRS(1)PAFVQLAPLSSK ; 92.096 0.0010754 54120000 2301.35 1516.84 2072.59 2355.4 1676.76 2558.2 1586.09 1905.51 1885.99 2017.69 TRUE FALSE FALSE 2119.195719 1647.948891 2149.402009 2345.653979 1656.765732 2027.600483 1630.591417 2486.491227 1679.101616 2087.804577 1.015035479 0.789321428 1.029503447 1.123502652 0.793544449 0.971163923 0.781007684 1.190959755 0.804242712 1 11.02777096 EPGPIAPSTNS(ph)SPVLK ddPTM_HeLa_Curcumin_4h_R1 1 EPGPIAPSTNSSPVLK 16 0 Q14674-2;Q14674 Q14674-2 ESPL1 Separin 1 0 EPGPIAPS(0.1)T(0.1)NS(0.413)S(0.386)PVLK 127.32 0.00060008 0 3732.9 2706.6 3371.4 3980 3816 4304.5 3131.1 2581.4 3781.6 3294 TRUE FALSE FALSE 3437.437026 2940.546444 3496.34705 3963.531815 3770.496692 3411.698178 3218.950239 3368.456977 3366.767941 3408.466255 1.00849965 0.862718368 1.025783091 1.16284907 1.106215057 1.000948205 0.944398447 0.988261794 0.987766253 1 11.73490698 -6.535608922 24.99845975 0.991182157 1.042410601 0.171228618 0.070516879 436.6107478 857377.1928 0.011927036 0.016873845 2.91E-07 6.535608922 0.051228444 EPLPGLTREPVAES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 EPLPGLTREPVAESPK 16 1 A0A0G2JNN3;C9JMY0;A0A087WUE4;Q96PV6-1;Q96PV6 A0A0G2JNN3 LENG8 Leukocyte receptor cluster member 8 1 0 EPLPGLT(0.002)REPVAES(0.998)PK 63.727 0.0152 21388000 4622 3684.6 4252.4 4233.3 4147.5 2608.6 3210.9 2253.2 4297.2 4301.1 TRUE FALSE FALSE 4256.163823 4003.080406 4409.997685 4215.783726 4098.043771 2067.546955 3300.989212 2940.190308 3825.807911 4450.562905 0.956320338 0.899454854 0.990885373 0.947247307 0.920792237 0.464558529 0.741701507 0.660633356 0.859623376 1 12.1197721 -5.39182838 6.076367484 0.969713661 0.63578477 0.772052056 0.077936339 0.063300782 2.863596066 0.009415682 0.021251008 4.06E-06 5.39182838 -0.333928891 EPPGLIFNKVEVS(ph)EDEPASK ddPTM_HeLa_Curcumin_4h_R1 2 EPPGLIFNKVEVSEDEPASK 20 1 O75683 O75683 SURF6 Surfeit locus protein 6 1 0 EPPGLIFNKVEVS(0.906)EDEPAS(0.094)K;EPPGLIFNKVEVS(0.972)EDEPAS(0.028)K ; 74.519 0.0020129 37217000 2644.1 2321.4 2549.7 3123.3 2100.02 2403.7 1595.35 1307.49 3246.2 3004.8 TRUE FALSE FALSE 2434.816695 2522.051472 2644.194125 3110.376612 2074.978633 1905.145525 1640.111227 1706.137682 2890.099982 3109.216576 0.783096525 0.81115336 0.85043742 1.000373096 0.667363814 0.612741338 0.527499834 0.548735554 0.929526751 1 11.6023354 -3.719346386 0.268154192 0.948289832 5.15E-25 0.719051846 0.089118426 5.655425827 0.247434475 0.058503662 1.857474432 0.000190833 3.719346386 -0.948289832 EPPPLLEVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 EPPPLLEVSPR 11 0 Q9ULI4 Q9ULI4 KIF26A Kinesin-like protein KIF26A 1 0 EPPPLLEVS(1)PR 92.295 0.015792 2773000 66.599 67.463 191.56 194.66 166.17 224.08 146.99 142.98 137.63 0 TRUE FALSE FALSE 61.32761888 73.29420111 198.6593821 193.8545485 164.1885313 177.6032821 151.1141438 186.5739438 122.5323333 0 0 EPPSS(ph)PLQPQK ddPTM_HeLa_Curcumin_4h_R1 1 EPPSSPLQPQK 11 0 A0A087X183;H0Y4V9;Q92615 A0A087X183 LARP4B La-related protein 4B 1 0 EPPS(0.213)S(0.787)PLQPQK 93.839 0.01485 11469000 1910.8 2046.5 1961.1 2202.3 2857.7 3005.3 2666 1666.6 1660.8 1558.8 TRUE FALSE FALSE 1759.558164 2223.390341 2033.780091 2193.187466 2823.623794 2381.966903 2740.800785 2174.738668 1478.614395 1612.968184 1.090882127 1.378446496 1.260892875 1.359721467 1.750576249 1.476760005 1.699228052 1.348283673 0.916704006 1 10.65550227 -6.8062815 0.766654491 1.020356739 1.57150214 0.738617804 0.13331417 0.197747915 0.234848254 0.027150178 0.043517862 1.56E-07 6.8062815 0.5511454 EPQIQMT(ph)VT(ph)MCK ddPTM_HeLa_Curcumin_4h_R1 1 EPQIQMTVTMCK 12 0 Q96PS1 Q96PS1 FANCD2OS FANCD2 opposite strand protein 2 0 EPQIQMT(1)VT(1)MCK 43.897 0.009648 0 1954.9 1580.4 1918.2 1717.7 1775.3 2794.9 2023.1 1623.9 2142.5 1772.2 TRUE FALSE FALSE 1800.167602 1717.002734 1989.290179 1710.592613 1754.130707 2215.206235 2079.862741 2119.019634 1907.47311 1833.783818 0.981668387 0.936316875 1.084800814 0.932821304 0.956563522 1.207997482 1.134191894 1.155544952 1.040184285 1 10.84060786 -5.264266033 24.99814438 0.987605335 1.162739492 0.746883893 0.046808966 77.43301025 684799.6197 0.005803665 0.013527117 5.44E-06 5.264266033 0.175134157 EPS(ph)PALGPNLDGSGLLPR ddPTM_HeLa_Curcumin_4h_R1 2 EPSPALGPNLDGSGLLPR 18 0 Q9BRZ2 Q9BRZ2 TRIM56 E3 ubiquitin-protein ligase TRIM56 1 0 EPS(0.512)PALGPNLDGS(0.488)GLLPR;EPS(1)PALGPNLDGSGLLPR ; 178.52 8.73E-07 29646000 1190.06 930.37 1089.99 1178.54 1213.41 1215.08 1235.14 686.56 1098.37 721.15 TRUE FALSE FALSE 1095.865495 1010.787037 1130.385988 1173.663514 1198.940878 963.0587112 1269.794704 895.8889835 977.881559 746.2099088 1.468575373 1.354561264 1.514836475 1.572832925 1.60670726 1.290600272 1.701658862 1.200585751 1.310464452 1 9.543437707 -9.187638669 0.581017105 0.931754182 1.485619388 0.271996042 0.171340153 0.558118989 0.280969228 0.165519393 0.030788843 6.49E-10 9.187638669 0.553865206 EPSAPSIPTPAY(ph)QSSPAGGHAPTPPTPAPR ddPTM_HeLa_Curcumin_4h_R1 2 EPSAPSIPTPAYQSSPAGGHAPTPPTPAPR 30 0 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 1 0 EPSAPSIPT(0.064)PAY(0.733)QS(0.117)S(0.086)PAGGHAPTPPTPAPR;EPSAPSIPT(0.003)PAY(0.425)QS(0.187)S(0.385)PAGGHAPTPPTPAPR ; 96.312 2.86E-07 108616000 3760.3 3302 2981.3 3324.9 3868.7 6761.2 4838.3 2637.5 4079.3 2453 TRUE FALSE FALSE 3462.668287 3587.410167 3091.789601 3311.142445 3822.568279 5358.850906 4974.049676 3441.661608 3631.810996 2538.241567 1.364199662 1.413344661 1.218083275 1.30450249 1.505990733 2.111245428 1.959643928 1.355923586 1.430837412 1 11.30961366 -6.078677501 0.215899458 0.932101206 2.095670347 0.291583279 0.265202827 3.082562894 0.301337886 0.391372028 1.109756961 8.34E-07 6.078677501 1.163569141 EPSAPSIPTPAYQS(ph)SPAGGHAPT(ph)PPTPAPR ddPTM_HeLa_Curcumin_4h_R1 1 EPSAPSIPTPAYQSSPAGGHAPTPPTPAPR 30 0 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 2 0 EPSAPS(0.001)IPT(0.014)PAY(0.378)QS(0.57)S(0.57)PAGGHAPT(0.422)PPT(0.046)PAPR 53.798 0.0037863 7920200 915.38 756.4 698.41 854.12 870.61 1215.5 1050.9 564.1 738.43 705.28 TRUE FALSE FALSE 842.9267071 821.7798455 724.293689 850.5858778 860.2285444 963.3915985 1080.385426 736.0914932 657.4260765 729.7884275 1.155028876 1.126052174 0.992470779 1.165523932 1.178736894 1.320097116 1.480409095 1.00863684 0.900844754 1 9.511334464 -5.70030661 2.045406272 1.075181619 1.285974364 0.347983362 0.131740027 0.25690133 2.182968567 0.017986002 0.040998617 1.99E-06 5.70030661 0.210792745 EPSAT(ph)PPISNLTK ddPTM_HeLa_Curcumin_4h_R1 2 EPSATPPISNLTK 13 0 F5H1T5;F5H6A0;J3KP58;P30622-2;P30622-1;P30622 F5H1T5 CLIP1 CAP-Gly domain-containing linker protein 1 1 0 EPS(0.143)AT(0.855)PPIS(0.002)NLTK;EPS(0.176)AT(0.817)PPIS(0.007)NLTK ; 141.82 0.0026482 22516900 5897.7 5044.2 5043.4 5243 5352.9 6730.1 5856.6 2829 5498.6 4768.4 TRUE FALSE FALSE 5430.890822 5480.198171 5230.312841 5221.305855 5289.070164 5334.201396 6020.920434 3691.549077 4895.417337 4934.101545 1.100684851 1.110678027 1.060033482 1.058208026 1.071941896 1.081088694 1.220266826 0.748170471 0.992159827 1 12.26857169 -4.243137979 24.95657208 1.066682137 0.748170193 0.722573522 0.060853431 1719.699729 2345020.868 0.008603064 0.387444697 5.71E-05 4.243137979 -0.318511944 EPSDK(ac)AVK ddPTM_HeLa_Curcumin_4h_R1 1 EPSDKAVK 8 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2;Q68E03 A0A0R4J2E8 MATR3;DKFZp686L22104 Matrin-3 0 1 EPSDK(1)AVK 92.062 0.020312 4039800 1686.7 1650.6 1700.7 1848.2 1785.9 2027.2 1799.8 1273.3 1839.4 1469.4 FALSE TRUE FALSE 1553.195915 1793.270509 1763.729438 1840.552638 1764.604309 1606.735869 1850.297544 1661.523308 1637.622422 1520.461541 1.021529235 1.179425103 1.159996087 1.210522324 1.160571486 1.056742197 1.2169315 1.092775624 1.077056129 1 10.57029361 -7.296269321 6.9622231 1.009910089 1.155224127 0.530247775 0.050825187 0.086105636 13.70909876 0.007477965 0.008596976 5.06E-08 7.296269321 0.145314038 EPST(ph)ASGGGQLNR ddPTM_HeLa_Curcumin_4h_R1 1 EPSTASGGGQLNR 13 0 A0A075B785;A0A2R8Y566;Q9P260;Q9P260-2 A0A075B785 KIAA1468 LisH domain and HEAT repeat-containing protein KIAA1468 1 0 EPS(0.008)T(0.923)AS(0.069)GGGQLNR 103.13 0.015999 9485000 408.15 479.01 406.04 539.83 536.5 504.58 407.41 237.84 508.86 484.9 TRUE FALSE FALSE 375.8444968 520.41349 421.0881996 537.5963265 530.1025879 399.9244202 418.8408281 310.3563211 453.0393311 501.7502389 0.749066902 1.037196297 0.839238663 1.071442094 1.056506897 0.797058754 0.834759599 0.618547431 0.902918018 1 8.970825588 -4.19996316 1.516687233 0.909961011 0.481820486 0.44188937 0.106280712 1.212892656 2.268692657 0.018390102 0.807225044 6.31E-05 4.19996316 -0.428140525 EPTGVEENKTDSLFVLPSRDDAT(ph)PVRDEPMDAESITFK ddPTM_HeLa_Curcumin_4h_R1 1 EPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFK 38 3 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 0 EPT(0.002)GVEENKT(0.005)DS(0.032)LFVLPS(0.028)RDDAT(0.82)PVRDEPMDAES(0.083)IT(0.032)FK 46.033 0.0035496 13534000 699.83 783.06 817.36 687.46 685.43 997.21 868.13 704.35 742.94 755.87 TRUE FALSE FALSE 644.437717 850.7442172 847.6520806 684.6154727 677.2566949 790.3774051 892.4873913 919.1030726 661.4413407 782.1364262 0.823945408 1.087718445 1.083764996 0.875314651 0.86590609 1.010536498 1.141089152 1.175118613 0.84568538 1 9.611276465 -4.843590278 3.000255647 0.934896684 1.166903133 0.483276855 0.088887019 0.175745187 3.11665756 0.014191322 0.054933924 1.43E-05 4.843590278 0.232006449 EPTPSIAS(ph)DIS(ph)LPIATQELR ddPTM_HeLa_Curcumin_4h_R1 1 EPTPSIASDISLPIATQELR 20 0 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 2 0 EPT(0.021)PS(0.025)IAS(0.955)DIS(0.993)LPIAT(0.006)QELR 77.08 0.0084136 1075500 267.51 194.99 259.04 290.32 201.49 280.75 199.66 240.1 271.54 210.58 TRUE FALSE FALSE 246.3363012 211.8440667 268.6402503 289.1187328 199.0873633 222.5192853 205.2619222 313.3053847 241.7527414 217.8976393 1.13051386 0.972218274 1.232873615 1.326855737 0.913673796 1.02121017 0.942010767 1.437855801 1.109478479 1 7.767506756 -9.403820416 0.693167584 0.983519141 1.114407259 0.005121351 0.165631135 2.544282534 1.730331374 0.206267675 0.032676382 3.95E-10 9.403820416 0.130888117 EPTPSIAS(ph)DISLPIATQELR ddPTM_HeLa_Curcumin_4h_R1 3 EPTPSIASDISLPIATQELR 20 0 A0A499FIX8;H7BXI1;A0A087WXU3;A0FGR8-5;A0FGR8-2;A0FGR8;A0FGR8-6 A0A499FIX8 ESYT2 Extended synaptotagmin-2 1 0 EPTPS(0.012)IAS(0.687)DIS(0.301)LPIAT(0.001)QELR;EPTPS(0.003)IAS(0.992)DIS(0.004)LPIATQELR;EPT(0.002)PS(0.18)IAS(0.799)DIS(0.019)LPIATQELR ;; 218.88 8.31E-19 12082000 1441.07 1320.31 1483.95 1750.99 1830.67 1554.5 1147.53 1208.13 1681.46 1431.09 TRUE FALSE FALSE 1327.007789 1434.431713 1538.946492 1743.744867 1808.840456 1232.079177 1179.726603 1576.483275 1497.008045 1480.820271 0.896130216 0.968673742 1.039252719 1.177553348 1.22151249 0.832024791 0.796671025 1.064601361 1.010931626 1 10.53218083 -2.687528516 15.10741836 0.976045319 1.214342676 0 0.131850544 0 0 0.01822713 0 0.00205339 2.687528516 0.238297357 EPVAES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 EPVAESPK 8 0 A0A0G2JNN3;C9JMY0;A0A087WUE4;Q96PV6-1;Q96PV6 A0A0G2JNN3 LENG8 Leukocyte receptor cluster member 8 1 0 EPVAES(1)PK;EPVAES(1)PK ; 111.27 0.010926 54173000 9981.6 9222.4 10801.4 10297.4 11396.4 10146.8 10561 7263 10397.7 9501.8 TRUE FALSE FALSE 9191.545827 10019.54316 11201.70939 10254.79209 11260.50537 8042.239302 10857.31324 9477.455265 9257.098324 9831.986843 0.934861486 1.019076136 1.139312894 1.043003032 1.145292966 0.817966849 1.104284761 0.963941004 0.941528754 1 13.26326727 -7.018249229 22.93436019 0.969646904 1.037930861 0.121644694 0.091112094 421.6591597 529912.7802 0.014351613 0.017780065 9.59E-08 7.018249229 0.068283956 EPVRADS(ph)PVHMEQQSR ddPTM_HeLa_Curcumin_4h_R1 1 EPVRADSPVHMEQQSR 16 1 O95402 O95402 MED26 Mediator of RNA polymerase II transcription subunit 26 1 0 EPVRADS(1)PVHMEQQSR 56.46 0.018111 4322300 3039 2754.1 3008.6 2896.6 3292.5 3631.3 3031.7 2020 3325.4 2610 TRUE FALSE FALSE 2798.459943 2992.152132 3120.101363 2884.614637 3253.239088 2878.127447 3116.761343 2635.888701 2960.61194 2700.697306 1.036199035 1.107918361 1.155294729 1.068099942 1.204592266 1.0656979 1.154058004 0.976003011 1.096239824 1 11.39911624 -7.382657147 2.648066551 1.01452487 1.109712331 0.110582324 0.064509953 0.211712097 2.787326779 0.009810921 0.01112999 4.14E-08 7.382657147 0.095187461 EPVS(ph)PMELTGPEDGAASSGAGR ddPTM_HeLa_Curcumin_4h_R1 2 EPVSPMELTGPEDGAASSGAGR 22 0 A0A0C4DFL8;F5GX28;O94953;K7EQ54 A0A0C4DFL8 KDM4B Lysine-specific demethylase 4B 1 0 EPVS(1)PMELTGPEDGAASSGAGR;EPVS(0.999)PMELT(0.001)GPEDGAASSGAGR ; 136.46 2.56E-05 8097200 1069.82 989.13 901.33 1314.14 1280.62 1217.55 1164.23 1328.35 1113.56 1033.68 TRUE FALSE FALSE 985.1426181 1074.62599 934.7340827 1308.702437 1265.349443 965.0164054 1196.89516 1733.3578 991.405254 1069.600303 0.921038088 1.004698659 0.873909703 1.223543442 1.183011485 0.902221515 1.119011613 1.620565921 0.926893206 1 10.06285606 -4.282027703 2.98486454 0.989716487 1.709613644 0.732111328 0.11097778 0.137547516 1.821341886 0.015774113 0.229371621 5.22E-05 4.282027703 0.719897157 EQAAALGPASATPALSSS(ph)PPPPSTLYR ddPTM_HeLa_Curcumin_4h_R1 1 EQAAALGPASATPALSSSPPPPSTLYR 27 0 Q9P242 Q9P242 NYAP2 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 1 0 EQAAALGPASATPALS(0.009)S(0.107)S(0.884)PPPPSTLYR 131.36 1.26E-08 10385000 3496 3002.2 3163.5 3349.8 3389.9 4638.3 2988.6 1574.1 3121.7 2977.8 TRUE FALSE FALSE 3219.287911 3261.69679 3280.742093 3335.939415 3349.477657 3676.264296 3072.452073 2054.035844 2779.25732 3081.278328 1.044789716 1.058553121 1.064734095 1.082647869 1.087041578 1.193097119 0.997135521 0.66661808 0.901981913 1 11.58931329 -4.277475515 4.265366384 1.047006969 0.642601018 0.733459163 0.069485564 0.065859889 2.719091598 0.008254784 0.078355638 5.28E-05 4.277475515 -0.404405951 EQAEAEVASLNR ddPTM_HeLa_Curcumin_4h_R1 2 EQAEAEVASLNR 12 0 A0A087WWU8;P06753-2;P06753-5;P06753-3;P06753-6;P06753-4;D6R904;A0A494C0G0 A0A087WWU8 TPM3 Tropomyosin alpha-3 chain 0 0 ; ; 208.74 1.23E-20 10428400 3660.5 3389.8 3338.6 3290 3848.7 3927.2 3370 3310.4 3368.7 3303.5 FALSE FALSE TRUE 3370.767562 3682.799207 3462.331453 3276.386852 3802.806766 3112.654451 3464.55313 4319.725721 2999.162038 3418.296379 0.986095759 1.077378553 1.01288217 0.958485306 1.112485971 0.910586475 1.013532107 1.263707193 0.87738502 1 11.73906177 -4.264321129 5.744189834 1.000988036 1.271604042 0.597036543 0.066262229 0.053284217 7.542635991 0.006657004 0.05633278 5.44E-05 4.264321129 0.270616006 EQAEAEVASLNRR ddPTM_HeLa_Curcumin_4h_R1 1 EQAEAEVASLNRR 13 1 A0A087WWU8;P06753-2;P06753-5;P06753-3;P06753-6;P06753-4;D6R904;A0A494C0G0 A0A087WWU8 TPM3 Tropomyosin alpha-3 chain 0 0 115.12 0.00027688 6993000 1940.2 1792.4 1861.8 2094.3 1766.5 2443.8 1870.3 1679.3 2117.4 1801.7 FALSE FALSE TRUE 1786.631123 1947.327069 1930.799946 2085.634342 1745.435641 1936.928333 1922.775584 2191.310839 1885.126517 1864.308941 0.958334256 1.044530242 1.035665229 1.118717127 0.936237339 1.038952445 1.031361027 1.175401132 1.011166377 1 10.86442524 -7.205939614 7.210733724 0.980349645 1.050335142 0.189216882 0.059908297 0.284763771 32.25700746 0.00953843 0.011672811 6.22E-08 7.205939614 0.069985497 EQAEEERYFR ddPTM_HeLa_Curcumin_4h_R1 1 EQAEEERYFR 10 1 Q9UII2;A0A0B4J230;Q9UII2-3;Q9UII2-2 Q9UII2 ATPIF1 "ATPase inhibitor, mitochondrial" 0 0 92.611 0.015074 3932000 764.93 391.14 353.13 577.52 334.65 880.87 351.69 377.31 1316.4 984.6 FALSE FALSE TRUE 704.3849833 424.9483987 366.2173084 575.1303753 330.6595173 698.1676325 361.5574749 492.3500821 1171.994213 1018.814777 0.691376882 0.417100741 0.359454257 0.56450926 0.324553123 0.685274349 0.354880478 0.483257696 1.150350623 1 9.992676074 -8.006646035 0.755527903 0.959417588 0.449700273 0.766427315 0.129732595 0.185729517 0.232907117 0.038949063 0.027915109 9.85E-09 8.006646035 -0.509717315 down EQCCYNCGKPGHLAR ddPTM_HeLa_Curcumin_4h_R1 2 EQCCYNCGKPGHLAR 15 1 P62633-7;P62633-3;P62633-2;P62633-8;P62633-5;P62633;P62633-4;P62633-6 P62633-7 CNBP Cellular nucleic acid-binding protein 0 0 ; ; 98.337 0.0012756 4578600 4615.6 3405.6 3354.7 3840.3 4460.2 4740.1 3506.3 3322.1 3828.9 3837.6 FALSE FALSE TRUE 4250.27039 3699.964889 3479.028133 3824.409856 4407.015028 3756.949828 3604.677341 4334.992997 3408.879249 3970.956314 1.070339247 0.931756634 0.876118461 0.963095424 1.109812015 0.946107066 0.907760513 1.091674814 0.858452972 1 11.95527077 -7.263440606 24.9935577 1.033215755 0.972379549 0 0.090559921 280.9446318 3508720.92 0.012462843 0.014628517 5.45E-08 7.263440606 -0.060836206 EQDGFTGKEEVVEQGELNATEEVWIPGEGHPES(ph)PEPK ddPTM_HeLa_Curcumin_4h_R1 2 EQDGFTGKEEVVEQGELNATEEVWIPGEGHPESPEPK 37 1 P48681 P48681 NES Nestin 1 0 EQDGFTGKEEVVEQGELNATEEVWIPGEGHPES(1)PEPK;EQDGFTGKEEVVEQGELNAT(0.004)EEVWIPGEGHPES(0.996)PEPK ; 104.71 4.03E-15 19315100 4390.7 3408 3621.1 4143.9 3733.5 4130.8 3397.7 3673.3 4650.3 3959 TRUE FALSE FALSE 4043.171462 3702.572334 3755.301151 4126.75364 3688.980451 3274.025516 3493.030318 4793.27226 4140.173724 4096.574955 0.986963868 0.903821454 0.916692894 1.007366809 0.900503589 0.799210451 0.852670915 1.170068243 1.010642737 1 12.0002025 -7.349220484 5.990366122 0.994204469 0.928064766 0.082378548 0.094314171 0.41784774 23.06943845 0.015653048 0.017847409 4.47E-08 7.349220484 -0.066139702 EQDLMCIK ddPTM_HeLa_Curcumin_4h_R1 1 EQDLMCIK 8 0 A0A0C4DG80;Q9P2N7-2;Q9P2J3;Q9P2N7-3;Q9P2N7-4;Q9P2N7;Q9P2N7-5 A0A0C4DG80 KLHL13;KLHL9 Kelch-like protein 13;Kelch-like protein 9 0 0 101.64 0.011915 89030000 1232 603.88 741.9 787.82 1051.9 1005.9 683.15 473.42 629.96 566.57 FALSE FALSE TRUE 1134.4859 656.0766964 769.3954666 784.5602096 1039.35678 797.2650012 702.3173504 617.7635786 560.8549641 586.2582653 1.935129903 1.119091594 1.312383146 1.338250147 1.772865034 1.359921127 1.197965798 1.053739649 0.956668754 1 9.195392547 -4.672997533 2.900616435 1.431229367 1.080576586 0.040345129 0.300927628 0.477073646 7.664783549 0.051168587 0.254749627 2.12E-05 4.672997533 -0.35065278 EQDLPLAEAVRPKT(ph)PPVVIK ddPTM_HeLa_Curcumin_4h_R1 2 EQDLPLAEAVRPKTPPVVIK 20 2 Q96A49 Q96A49 SYAP1 Synapse-associated protein 1 1 0 EQDLPLAEAVRPKT(1)PPVVIK;EQDLPLAEAVRPKT(1)PPVVIK ; 72.644 0.0088536 3052700000 10651.6 7862.7 8348.9 9153.5 8250.2 10511.6 7883.8 4529.5 9415.5 8983.1 TRUE FALSE FALSE 9808.51462 8542.316752 8658.317578 9115.625242 8151.821753 8331.37567 8104.99821 5910.523699 8382.643206 9295.262056 1.055216578 0.918996872 0.931476437 0.980674368 0.87698676 0.896303474 0.871949404 0.635864128 0.901818922 1 13.18227982 -3.18932129 0.418437293 1.02095405 4.16E-16 0.661969883 0.061687247 3.567476763 0.217285237 0.012607547 2.212820415 0.000646664 3.18932129 -1.02095405 EQDNSESPNGRT(ph)SPLVSQNNEQGSTLR ddPTM_HeLa_Curcumin_4h_R1 1 EQDNSESPNGRTSPLVSQNNEQGSTLR 27 1 A0A1W2PNZ9;Q15652-3;Q15652;H7BXU7 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 0 EQDNS(0.004)ES(0.037)PNGRT(0.479)S(0.479)PLVS(0.001)QNNEQGSTLR 63.657 0.001438 12560000 739.83 758.73 860.94 703.69 753.27 961.62 706.87 504.71 755.56 851.84 TRUE FALSE FALSE 681.2716748 824.3112404 892.8471938 700.7783172 744.2877472 762.1691723 726.7028698 658.5937556 672.6769583 881.4413766 0.772906393 0.935185552 1.012939961 0.795036784 0.844398467 0.86468504 0.824448329 0.747178171 0.76315564 1 9.783720811 -9.5260938 1.24125715 1.00125336 0.845857143 0 0.103519479 0.427635018 1.164245174 0.057126865 0.013225045 2.98E-10 9.5260938 -0.155396217 EQDNSESPNGRTS(ph)PLVSQNNEQGSTLR ddPTM_HeLa_Curcumin_4h_R1 1 EQDNSESPNGRTSPLVSQNNEQGSTLR 27 1 A0A1W2PNZ9;Q15652-3;Q15652;H7BXU7 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 0 EQDNS(0.007)ES(0.198)PNGRT(0.198)S(0.596)PLVS(0.002)QNNEQGSTLR 62.696 0.00096264 13538000 1732.7 1197.4 1452.3 1779.4 1547 1753.1 1601.9 1038.8 1315.5 1466.6 TRUE FALSE FALSE 1595.554967 1300.89792 1506.123516 1772.037314 1528.553035 1389.487298 1646.845003 1355.525338 1171.192941 1517.564241 1.051392042 0.857227579 0.992461126 1.167685207 1.007241074 0.915603611 1.085189647 0.893224354 0.771758394 1 10.56754187 -5.506271573 24.83069823 1.020035866 0.974173926 0 0.115931612 1673.721648 2502509.588 0.011959124 0.026081854 3.12E-06 5.506271573 -0.045861939 EQDRVHS(ph)PCPTSGSEK ddPTM_HeLa_Curcumin_4h_R1 1 EQDRVHSPCPTSGSEK 16 1 X6RLP6;Q96LT9-2;Q96LT9 X6RLP6 RNPC3 RNA-binding protein 40 1 0 EQDRVHS(0.997)PCPT(0.002)SGSEK 84.993 0.0040218 16275000 1286.2 1194.4 1192.1 982.74 974.63 1393.6 1082.8 1044.1 1199.7 1402.8 TRUE FALSE FALSE 1184.395913 1297.638614 1236.280275 978.6736823 963.0081738 1104.551651 1113.180454 1362.441284 1068.095912 1451.547196 0.815954119 0.893969289 0.851698297 0.674227945 0.663435661 0.760947804 0.76689236 0.938613149 0.735832713 1 10.50337577 -8.906234161 0.416282893 1.040773018 0.768772678 0 0.114512383 1.153453803 0.324193888 0.1358606 0.030656549 1.24E-09 8.906234161 -0.272000341 S(ph)TTPTSSPFR ddPTM_HeLa_Curcumin_4h_R1 1 STTPTSSPFR 10 0 E7EPN9;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-2;A0A2R8Y7F4;A0A2R8YET2;H7C5N8;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 0 S(0.351)T(0.351)T(0.253)PT(0.012)S(0.026)S(0.006)PFR 97.597 0.014172 162420000 6371.8 4645.5 5184.9 5204.5 5420.3 4631.9 2975.5 1184 5869 4416.3 TRUE FALSE FALSE 5867.465307 5047.03632 5377.056955 5182.965158 5355.666463 3671.191728 3058.984522 1544.99615 5225.185384 4569.766096 1.283974974 1.104440843 1.17665912 1.134186094 1.171978248 0.803365347 0.669396301 0.33809086 1.143425128 1 12.15790461 -4.685650984 1.260765541 1.14275144 0.274844357 0.913574205 0.081786087 0.204375832 0.44357134 0.016903815 0.187738379 2.06E-05 4.685650984 -0.867907082 down EQEEERLR ddPTM_HeLa_Curcumin_4h_R1 1 EQEEERLR 8 1 A0A087X0T7 REV__A0A0A0MRX2 GOLGA6L10 0 0 99.013 0.013479 3495000 1875 1685.8 1734.9 1727.9 1874.4 1956.7 1604.3 1811 2308.7 1831 FALSE FALSE TRUE 1726.591772 1831.51304 1799.19692 1720.750408 1852.049004 1550.858363 1649.31234 2363.165563 2055.441386 1894.627114 0.911309544 0.966687865 0.949631148 0.908226424 0.977526919 0.818555985 0.870520816 1.247298503 1.084879115 1 10.88769822 -4.253123256 24.74992833 0.94162746 1.247298679 0.633714662 0.069387896 388.0500369 1154860.338 0.008181824 0.123730021 5.58E-05 4.253123256 0.305671219 EQEVNILK ddPTM_HeLa_Curcumin_4h_R1 2 EQEVNILK 8 0 P35579 P35579 MYH9 Myosin-9 0 0 ; ; 121.96 0.0025138 13139000 6442.6 5621.3 6090.5 6656.5 6571.6 7106.8 5743.9 5213.9 6437 5835.4 FALSE FALSE TRUE 5932.661412 6107.180124 6316.219288 6628.957167 6493.237962 5632.76957 5905.058375 6803.594108 5730.877205 6038.179716 0.982524816 1.011427353 1.046046919 1.097840323 1.075363482 0.932858881 0.977953399 1.12676244 0.949106763 1 12.55989798 -6.958679968 4.094248154 0.991875071 1.038647237 0.211404206 0.054355881 0.328523675 11.99246882 0.008842505 0.011587124 1.10E-07 6.958679968 0.046772166 EQEVNILK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EQEVNILKK 9 1 P35579 P35579 MYH9 Myosin-9 0 1 ; EQEVNILK(1)K;EQEVNILK(1)K 135.55 0.00010178 16611900 3281.1 4129.3 2433.94 3425.46 4420 7025.5 5595.6 4932.9 7640.4 3449.2 FALSE TRUE FALSE 3021.397473 4486.218292 2524.143958 3411.286354 4367.294387 5568.332106 5752.597476 6436.918502 6802.267235 3569.059443 0.846552858 1.256974944 0.707229453 0.955794211 1.223654146 1.560167936 1.611796488 1.803533565 1.905899115 1 11.80132821 -5.340368736 1.680934224 0.934968738 1.714701327 0.274729758 0.336049462 0.101453238 0.545637707 0.020186417 0.065139276 4.57E-06 5.340368736 0.779732589 EQEVNILKK ddPTM_HeLa_Curcumin_4h_R1 1 EQEVNILKK 9 1 P35579 P35579 MYH9 Myosin-9 0 0 79.489 0.015571 0 2835.7 2408.2 2037.4 2839.9 2117.9 3322.8 2115.8 2276.9 3452.1 2831 FALSE FALSE TRUE 2611.251353 2616.354077 2112.907836 2828.149246 2092.645426 2633.613824 2175.163654 2971.116328 3073.413267 2929.377039 0.891401591 0.893143505 0.721282309 0.965443918 0.71436534 0.899035457 0.742534547 1.014248521 1.049169576 1 11.51637818 -8.334812196 0.635847926 0.995130031 0.840979803 0.314166658 0.097885988 0.629633911 0.548711582 0.044381213 0.022202717 4.63E-09 8.334812196 -0.154150229 EQFEGLGST(ph)PDAK ddPTM_HeLa_Curcumin_4h_R1 2 EQFEGLGSTPDAK 13 0 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 0 EQFEGLGS(0.001)T(0.999)PDAK;EQFEGLGS(0.117)T(0.883)PDAK ; 161.49 0.00068275 39620000 12009.1 9414.7 10082.6 9784.7 11082.5 14945.6 11714.5 2626.9 11405.2 9225.8 TRUE FALSE FALSE 11058.56706 10228.46472 10456.27003 9744.213504 10950.34843 11845.71409 12043.17734 3427.829717 10154.07809 9546.395863 1.158402314 1.071447787 1.095310751 1.020721709 1.147066242 1.240857205 1.261541792 0.359070561 1.063655671 1 13.22074045 -4.253670013 24.97370038 1.098958031 0.359070197 0.879773203 0.083873065 272.7121948 876580.0428 0.013445563 0.194434022 5.58E-05 4.253670013 -0.739887834 EQFLDGDGWTSR ddPTM_HeLa_Curcumin_4h_R1 4 EQFLDGDGWTSR 12 0 P27797;K7EJB9 P27797 CALR Calreticulin 0 0 ;;; ;;; 293.71 1.16E-71 332487700 14128.5 10333.6 11338.3 11345.8 12146.4 15452.6 11787.9 10114.3 11609.7 10785.1 FALSE FALSE TRUE 13010.21432 11226.79034 11758.50737 11298.85409 12001.56211 12247.55657 12118.63675 13198.10351 10336.14496 11159.88142 1.1658022 1.005995486 1.053640888 1.01245288 1.075420218 1.097462967 1.085910888 1.182638328 0.926187704 1 13.44603408 -9.689764683 1.572053977 1.000105167 1.093165077 0.357806048 0.059575406 0.449651789 2.006313174 0.042869855 0.009555205 2.04E-10 9.689764683 0.09305991 EQGDGAEDEEWDD ddPTM_HeLa_Curcumin_4h_R1 1 EQGDGAEDEEWDD 13 0 H0YMP5;Q7Z6K5 H0YMP5 ARPIN Arpin 0 0 123.96 0.018248 15396000 4473.8 3359.6 3738.9 3590.7 4166.5 4722.5 3990 3676.3 3987.4 3809.2 FALSE FALSE TRUE 4119.694009 3649.988854 3877.466923 3575.842635 4116.817209 3743.000266 4101.948661 4797.186946 3549.992196 3941.569416 1.045191287 0.926024248 0.98373681 0.907212904 1.044461425 0.949621806 1.040689184 1.217075342 0.900654491 1 11.94455447 -4.286431614 3.516220645 1.001734431 1.237407709 0.600250416 0.056384013 0.128900092 2.791157576 0.006823739 0.077199525 5.17E-05 4.286431614 0.235673278 EQGK(ac)TISNDDDVQK ddPTM_HeLa_Curcumin_4h_R1 1 EQGKTISNDDDVQK 14 1 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 0 1 EQGK(1)TISNDDDVQK 320.48 9.40E-155 2668100 812.51 842.34 835.67 798.57 725.18 1248.8 713.4 410.65 566.5 678.04 FALSE TRUE FALSE 748.1989761 915.1481162 866.6406653 795.2657289 716.5327021 989.7848031 733.416084 535.8552946 504.3563673 701.6018395 1.066415357 1.304369608 1.235231461 1.133500062 1.021281105 1.410750011 1.045345155 0.76375982 0.718864089 1 9.45450872 -7.497825688 11.55517868 1.029241592 1.141410261 0.130837337 0.192726261 1.247492083 570.4334536 0.028640359 0.031336588 3.18E-08 7.497825688 0.112168669 EQGTGNSYTDTSGPKET(ph)SSATPGRDSK ddPTM_HeLa_Curcumin_4h_R1 1 EQGTGNSYTDTSGPKETSSATPGRDSK 27 2 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 0 EQGTGNS(0.001)Y(0.002)T(0.002)DT(0.005)S(0.012)GPKET(0.285)S(0.285)S(0.285)AT(0.119)PGRDS(0.004)K 49.141 0.0093839 12186000 1696.7 1566.3 1405 1996.6 1271.3 2312.3 880.04 782.71 3101.8 2233.4 TRUE FALSE FALSE 1562.404405 1701.683993 1457.070536 1988.338598 1256.140578 1832.702915 904.7315539 1021.354676 2761.5403 2311.010484 0.676069804 0.736337634 0.630490665 0.860376278 0.543546032 0.793030983 0.39148743 0.441951555 1.194949274 1 11.17430809 -13.52287875 0.059660321 2.437066203 1.68E-10 0.660232293 0.137336812 145.9737418 0.68393491 31.45803238 5.973716657 3.00E-14 13.52287875 -2.437066203 EQGVEEHETLLLR ddPTM_HeLa_Curcumin_4h_R1 2 EQGVEEHETLLLR 13 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 ; ; 165.51 0.00014264 7073500 5294.8 4210.3 3599.3 3832.1 7190.8 10774 5887.7 5294.6 6241.1 4716 FALSE FALSE TRUE 4875.710993 4574.219571 3732.693224 3816.243786 7105.054406 8539.350952 6052.893016 6908.899167 5556.466944 4879.880649 0.999145541 0.937363001 0.76491486 0.782036296 1.455989381 1.749909796 1.240377266 1.415792652 1.138648124 1 12.25263015 -5.747434237 24.7744333 0.961246678 1.469749815 0.735445608 0.154869158 83.31250914 147374.8503 0.021767126 0.043357293 1.79E-06 5.747434237 0.508503137 EQIS(ph)DIDDAVR ddPTM_HeLa_Curcumin_4h_R1 4 EQISDIDDAVR 11 0 P53999 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 1 0 EQIS(1)DIDDAVR;EQIS(1)DIDDAVR;EQIS(1)DIDDAVR;EQIS(1)DIDDAVR ;;; 166.64 0.00026147 148082000 5376 5104.47 5505.6 5112.72 5595.72 6290.1 6118.2 5577.92 5109.8 4501.59 TRUE FALSE FALSE 4950.483927 5545.677642 5709.642379 5091.564919 5528.994694 4985.462356 6289.860226 7278.60213 4549.267724 4658.019917 1.062787196 1.190565463 1.225765986 1.093074957 1.18698391 1.070296487 1.350329182 1.562595751 0.976652699 1 12.18550109 -1 0.419536387 1.042044769 10.2679731 0.756205506 0.083219556 24.09817322 0.275696328 0.020049407 188.4044317 0.1 1 9.225928335 EQISDIDDAVR ddPTM_HeLa_Curcumin_4h_R1 6 EQISDIDDAVR 11 0 P53999 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 0 0 ;;;;; ;;;;; 218.15 3.73E-10 295606600 29391.8 24059.8 26513.6 25619.6 28015.6 35443 29219.6 29181.5 25564 24298.8 FALSE FALSE TRUE 27065.40802 26139.4219 27496.21734 25513.59288 27681.53227 28091.72228 30039.42334 38078.80501 22759.69316 25143.18149 1.076451205 1.039622687 1.093585446 1.014732081 1.100955831 1.117269996 1.194734379 1.51447839 0.905203391 1 14.61787959 -1 0.772434867 1.03996478 99.84586775 0.888424872 0.051768864 63.65180786 0.234989346 0.005637652 10982.47797 0.1 1 98.80590297 EQIVPKPEEEVAQK ddPTM_HeLa_Curcumin_4h_R1 2 EQIVPKPEEEVAQK 14 1 A0A087WXM6;J3QQT2;J3KRX5;A0A0A6YYL6;P18621;P18621-3;J3QLC8;A0A0A0MRF8;P18621-2 A0A087WXM6 RPL17;RPL17-C18orf32 60S ribosomal protein L17 0 0 ; ; 166.62 3.07E-05 12155600 7964.2 7517.6 7793.1 8095.9 9131.1 9774.8 7988 7422.7 8041.7 7041.7 FALSE FALSE TRUE 7333.825166 8167.387846 8081.919142 8062.401311 9022.217596 7747.396295 8212.121781 9685.84706 7159.545629 7286.398551 1.006508924 1.120908744 1.109178847 1.10650018 1.238227299 1.063268258 1.127048119 1.329305142 0.98259045 1 12.83099019 -1 0.171599103 0.961051265 2.160545699 0.62101562 0.063429442 28.16408061 0.297468987 0.093964138 8.742113181 0.1 1 1.199494434 EQIVVDLSHPGVSEDDQVSR ddPTM_HeLa_Curcumin_4h_R1 1 EQIVVDLSHPGVSEDDQVSR 20 0 O60701;O60701-3;O60701-2 O60701 UGDH UDP-glucose 6-dehydrogenase 0 0 121.47 8.48E-05 7106600 2335 1839 1701 1848.9 2168.5 2837.3 1997.4 2252.7 2333.4 1904.6 FALSE FALSE TRUE 2150.182286 1997.954966 1764.040556 1841.249742 2142.642054 2248.811997 2053.441668 2939.53786 2077.431858 1970.784708 1.091028501 1.013786517 0.895095517 0.934272391 1.087202496 1.141074409 1.041941141 1.491557067 1.054114054 1 10.94455447 -1.885562097 1.245581833 1.028068187 199.9746958 0.789432047 0.0712904 234.9151168 1.087589785 0.01142779 132727.2496 0.013014812 1.885562097 198.9466276 EQLAALK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EQLAALKK 8 1 Q9UII2 Q9UII2 ATPIF1 "ATPase inhibitor, mitochondrial" 0 1 ; EQLAALK(1)K;EQLAALK(1)K 122.13 0.00084064 9553700 7777.2 6716 5700.8 6581.8 11242.8 14394.6 10556.8 11261.5 12862.7 7053.5 FALSE TRUE FALSE 7161.626414 7296.501114 5912.076663 6554.566256 11108.73695 11408.9977 10852.9954 14695.07951 11451.69399 7298.6086 0.98123174 0.999711248 0.810027909 0.898056961 1.522034892 1.563174342 1.486995123 2.013408351 1.569024265 1 12.83340574 -5.678717624 4.319880453 0.970525444 1.648900626 0.603036791 0.237071916 0.059865858 2.079190383 0.020144143 0.04104273 2.10E-06 5.678717624 0.678375182 EQLAIAEFAR ddPTM_HeLa_Curcumin_4h_R1 1 EQLAIAEFAR 10 0 P17987;E7EQR6;F5H282 P17987 TCP1 T-complex protein 1 subunit alpha 0 0 105.46 0.0067281 1914000 1138.6 956.11 1169.3 1097.6 1149.6 1359.6 1220.5 1138 1084.2 909.76 FALSE FALSE TRUE 1048.478609 1038.751888 1212.635287 1093.058422 1135.891771 1077.603634 1254.743945 1484.970961 965.2659725 941.3740923 1.113774659 1.103442188 1.288154514 1.161130767 1.206631646 1.144713502 1.332885572 1.577450424 1.025379794 1 9.878624339 -1 0.273042179 1.033373873 4.409613579 0.778949132 0.075744706 16.69507787 0.212081693 0.036281308 27.01538151 0.1 1 3.376239706 EQLART(ph)LALKPT(ph)SLELFRTK ddPTM_HeLa_Curcumin_4h_R1 1 EQLARTLALKPTSLELFRTK 20 3 F8W9E7;Q96BJ8-2;Q96BJ8;Q96BJ8-3 F8W9E7 ELMO3 Engulfment and cell motility protein 3 2 0 EQLART(1)LALKPT(0.333)S(0.333)LELFRT(0.333)K 60.949 0.0048355 0 1412.4 1011.2 1027.1 1421 1109.2 1390.5 1163.3 1113.3 1320.5 1363.6 TRUE FALSE FALSE 1300.60705 1098.603622 1065.16523 1415.120279 1095.973514 1102.094626 1195.939067 1452.740045 1175.644454 1410.984999 0.921772415 0.778607585 0.754908968 1.002930775 0.776743563 0.781081746 0.847591625 1.029592835 0.83320833 1 10.46248693 -7.770383322 1.706573359 0.975665142 0.850328028 0 0.101565853 0.31388996 1.905355495 0.018898945 0.018267585 1.70E-08 7.770383322 -0.125337113 EQLDT(ph)SNESAEPK ddPTM_HeLa_Curcumin_4h_R1 1 EQLDTSNESAEPK 13 0 Q96DX7 Q96DX7 TRIM44 Tripartite motif-containing protein 44 1 0 EQLDT(0.558)S(0.441)NES(0.001)AEPK 202.32 2.29E-08 12932000 3679 3075.4 3363.9 3505.8 3431.8 4228 2550.3 1995.6 2969.9 2442.8 TRUE FALSE FALSE 3387.803268 3341.223872 3488.569093 3491.293929 3390.878026 3351.065141 2621.854554 2604.049253 2644.1094 2527.687118 1.340277934 1.321850259 1.380142767 1.381220762 1.341494365 1.325743648 1.037254388 1.03021028 1.046058818 1 11.30360218 -9.311959994 1.024313281 0.999217595 1.278685917 0.3828644 0.124332866 0.46145712 0.863184685 0.093483653 0.024594623 4.88E-10 9.311959994 0.279468321 EQLDTS(ph)NESAEPK ddPTM_HeLa_Curcumin_4h_R1 1 EQLDTSNESAEPK 13 0 Q96DX7 Q96DX7 TRIM44 Tripartite motif-containing protein 44 1 0 EQLDT(0.026)S(0.855)NES(0.119)AEPK 191.63 7.11E-06 11241000 4401.9 3934.1 3833.9 3514.3 4378.6 5118.7 3437.2 2430.6 3350.6 3343.9 TRUE FALSE FALSE 4053.48497 4274.146074 3975.987707 3499.758758 4326.388055 4057.02392 3533.638581 3171.678751 2983.047563 3460.100276 1.171493496 1.235266534 1.149096092 1.011461657 1.250364934 1.172516285 1.021253229 0.916643593 0.862127489 1 11.75659813 -4.490061635 3.863126342 1.110460863 0.928091345 0.214487807 0.11333769 0.227248936 6.955023501 0.013768762 0.082011865 3.24E-05 4.490061635 -0.182369518 EQLEEEEEAKHNLEK ddPTM_HeLa_Curcumin_4h_R1 4 EQLEEEEEAKHNLEK 15 1 P35579 P35579 MYH9 Myosin-9 0 0 ;;; ;;; 154.69 0.00033357 101076200 16162 12503.1 14690.8 13415.9 14774.5 15439.2 12653.2 12355.2 15074.3 13001.3 FALSE FALSE TRUE 14882.76065 13583.81225 15235.25397 13360.38856 14598.32374 12236.93588 13008.21474 16122.2436 13420.687 13453.09421 1.106270455 1.009716578 1.132472109 0.993108972 1.085127593 0.909600104 0.966931067 1.198404126 0.997591097 1 13.71565041 EQLQLLEEQHR ddPTM_HeLa_Curcumin_4h_R1 2 EQLQLLEEQHR 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 126.12 0.0027161 8876700 7751.7 6101.6 6936.7 6720.9 6672.8 7647.1 6758.9 5738 7162.2 7129 FALSE FALSE TRUE 7138.144765 6628.995116 7193.780204 6693.090697 6593.231218 6061.005259 6948.536543 7487.489785 6376.524579 7376.732219 0.967656755 0.898635726 0.975198772 0.907324612 0.893787523 0.821638238 0.941953203 1.015014449 0.864410472 1 12.84876615 -7.53568193 0.834420357 0.993420435 0.914995736 0 0.063961432 0.493917058 0.719963284 0.013186595 0.01332262 2.91E-08 7.53568193 -0.078424699 EQLRQEQALLEEIER ddPTM_HeLa_Curcumin_4h_R1 2 EQLRQEQALLEEIER 15 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 188.39 3.24E-06 27854100 2970.4 2465.66 2572.2 2998.9 2846.1 3526.6 2397.4 2296.43 3470.6 2750.6 FALSE FALSE TRUE 2735.289706 2678.780664 2667.527995 2986.491346 2812.162116 2795.143407 2464.664592 2996.600936 3089.883863 2846.183145 0.961037841 0.941183517 0.937229918 1.049296969 0.988046789 0.982067304 0.865954321 1.05284895 1.085623695 1 11.47481278 -6.366635545 0.003216695 1.944716177 2.23E-08 0.026656431 0.060845669 73739.57363 102.3034438 30693.20734 31154.62694 4.30E-07 6.366635545 -1.944716155 EQLSAQELMES(ph)GLQIQKSPEPEVLSTQEDLFDQSNK ddPTM_HeLa_Curcumin_4h_R1 1 EQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNK 36 1 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 EQLSAQELMES(0.471)GLQIQKS(0.471)PEPEVLS(0.046)T(0.011)QEDLFDQSNK 92.48 1.93E-11 5991500 1209.6 884.28 839.88 948.96 1013.9 1095 940.32 684.4 1284.1 1074.1 TRUE FALSE FALSE 1113.858884 960.7132229 871.0066916 945.033455 1001.809905 867.8846568 966.7028485 893.0704094 1143.237443 1111.424895 1.002189971 0.86439779 0.783684706 0.850289983 0.901374361 0.780875668 0.869786931 0.803536445 1.028623209 1 10.11819475 -7.208700454 4.107076408 1.001432358 0.834502061 0.827761299 0.036497172 0.058748602 2.081248926 0.005578494 0.006778069 6.18E-08 7.208700454 -0.166930298 EQLSAQELMESGLQIQKS(ph)PEPEVLSTQEDLFDQSNK ddPTM_HeLa_Curcumin_4h_R1 1 EQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNK 36 1 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 EQLSAQELMES(0.063)GLQIQKS(0.809)PEPEVLS(0.095)T(0.033)QEDLFDQSNK 106.77 7.75E-15 5959900 1996.5 1418 1724.7 1952.9 1592 2032.7 1320.2 1513.2 1929.8 1687.6 TRUE FALSE FALSE 1838.474918 1540.565602 1788.618899 1944.819417 1573.01644 1611.095107 1357.241259 1974.567714 1718.105768 1746.243974 1.052816757 0.882216703 1.024266326 1.11371575 0.900799924 0.922605965 0.777234613 1.13075134 0.98388644 1 10.77003942 -5.72696346 24.98994102 1.019120482 0.921001089 0.119588037 0.097741763 222.335984 161159.6685 0.013037613 0.026074184 1.88E-06 5.72696346 -0.098119393 ETPS(ph)QENGPTAK ddPTM_HeLa_Curcumin_4h_R1 3 ETPSQENGPTAK 12 0 O15355 O15355 PPM1G Protein phosphatase 1G 1 0 ET(0.001)PS(0.999)QENGPTAK;ET(0.002)PS(0.998)QENGPTAK;ETPS(0.999)QENGPT(0.001)AK ;; 172.09 0.00013467 49438000 5753.64 6190.4 5566.05 5499.36 5808.32 3550.33 6175.31 13506.7 5430.25 5503.2 TRUE FALSE FALSE 5298.233323 6725.470592 5772.332709 5476.605105 5739.059578 2813.951538 6348.572579 17624.83065 4834.565161 5694.43579 0.930422876 1.181060045 1.01367948 0.961746748 1.007836384 0.494158094 1.114872976 3.095096916 0.848998099 1 12.47533719 -4.265683404 4.799425238 0.957540275 3.207466977 0.935617619 0.16924631 0.027542124 1.808554422 0.021826711 0.205319497 5.42E-05 4.265683404 2.249926702 up EQMIDLQNLLTTQS(ph)PSVK ddPTM_HeLa_Curcumin_4h_R1 1 EQMIDLQNLLTTQSPSVK 18 0 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 0 EQMIDLQNLLTT(0.001)QS(0.999)PSVK 285.96 1.43E-136 0 4276.8 3764 4085.9 4318.5 4265.4 6231.3 5573.1 2724 4045.6 3096.4 TRUE FALSE FALSE 3938.286767 4089.343388 4237.327048 4300.631191 4214.537891 4938.858139 5729.466187 3554.53506 3601.807802 3203.99967 1.229178269 1.276324535 1.3225117 1.342269549 1.315398978 1.541466494 1.788223089 1.109405564 1.124159854 1 11.64565828 -7.43647658 0.304421859 0.959044926 1.531312635 0.400682348 0.166359141 0.831862733 0.255924207 0.170806619 0.165578642 3.66E-08 7.43647658 0.572267709 EQMMNSSISSGSGS(ph)LR ddPTM_HeLa_Curcumin_4h_R1 2 EQMMNSSISSGSGSLR 16 0 C9JUA9;A0A0C4DFT3;A0A590UKA8;A0A590UJC5;A0A590UJR5;A0A590UJ08;A0A590UJ81;A0A590UJ18;A0A590UJ68;A0A590UJ25;A0A590UJS9;A0A590UJX2;A0A590UK48;A0A590UJR4;A0A590UJD9;A0A590UK81;A0A590UJ29;A0A590UJ64;E7EQD7;A0A590UK02;A0A590UK70;A0A590UJL2;Q12959-7;Q12959;Q12959-4;Q12959-5;Q12959-6;Q12959-3;Q12959-9;Q12959-8;Q12959-2 C9JUA9 DLG1 Disks large homolog 1 1 0 EQMMNSSIS(0.01)S(0.161)GS(0.029)GS(0.799)LR;EQMMNSSISSGS(0.049)GS(0.951)LR ; 112.12 0.00063597 44560000 6224.6 4528.1 4512.1 5435.5 5565.3 6685.2 5111.5 3725.2 5982.8 4687.5 TRUE FALSE FALSE 5731.916342 4919.488787 4679.322395 5413.009341 5498.937432 5298.614162 5254.914933 4860.996331 5326.501808 4850.390276 1.181743327 1.014245969 0.96473111 1.115994597 1.133710304 1.09240986 1.083400435 1.00218664 1.098159427 1 12.24388512 -9.770462368 1.743337694 0.999891853 1.092429933 0 0.070519329 0.512909357 2.820513679 0.053145748 0.011308209 1.70E-10 9.770462368 0.092538081 EQMNEHHKRAYT(ph)YAPS(ph)Y(ph)EDFIK ddPTM_HeLa_Curcumin_4h_R1 1 EQMNEHHKRAYTYAPSYEDFIK 22 2 A0A494C0S0;Q9H3E2 A0A494C0S0 SNX25 Sorting nexin-25 3 0 EQMNEHHKRAY(0.466)T(0.523)Y(0.271)APS(0.8)Y(0.941)EDFIK 43.696 0.013398 21296000 889.87 555.9 476.31 714.15 694.52 695.02 535.97 737.99 706.99 500.07 TRUE FALSE FALSE 819.4358505 603.949519 493.9624676 711.1950365 686.2383026 550.8650175 551.0078757 962.9997537 629.4349658 517.4473953 1.583611896 1.167170855 0.954613884 1.374429639 1.326199163 1.06458168 1.064857763 1.861058269 1.216423102 1 9.015268393 -9.70141822 1.596815791 1.000351732 1.32337869 0.05028598 0.263502745 0.561393932 2.586295866 0.188166238 0.04171939 1.99E-10 9.70141822 0.323026958 EQNSALPTS(ph)SQDEELMEVVEK ddPTM_HeLa_Curcumin_4h_R1 2 EQNSALPTSSQDEELMEVVEK 21 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 EQNS(0.018)ALPT(0.113)S(0.434)S(0.434)QDEELMEVVEK;EQNSALPT(0.006)S(0.497)S(0.497)QDEELMEVVEK ; 74.819 0.0012434 8293400 3670.1 3440 3516.7 3791.19 4594 4877 4687 4433.1 3563.1 3540.76 TRUE FALSE FALSE 3379.607712 3737.338272 3647.031996 3775.50306 4539.21955 3865.455225 4818.504606 5784.731783 3172.236844 3663.801146 0.92243208 1.020071265 0.995423018 1.030487985 1.238937205 1.055039581 1.315165429 1.578888032 0.865832156 1 11.83912549 -1.000000025 0.464220083 0.964617393 16.50835907 0.871044153 0.073192726 17.84124274 0.186712962 0.01397916 267.2554029 0.099999994 1.000000025 15.54374167 EQNSALPTSS(ph)QDEELMEVVEK ddPTM_HeLa_Curcumin_4h_R1 1 EQNSALPTSSQDEELMEVVEK 21 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 EQNS(0.002)ALPT(0.021)S(0.129)S(0.848)QDEELMEVVEK 69.857 0.0015338 8167400 4373 3427 3815.4 3599.8 4647.4 4684 4189.1 4386.5 3306.5 2686.9 TRUE FALSE FALSE 4026.872436 3723.21461 3956.80208 3584.904981 4591.98279 3712.4856 4306.634872 5723.923657 2943.785222 2780.269575 1.448374817 1.339155974 1.423172097 1.289409133 1.651632213 1.335296992 1.548999029 2.058765707 1.058812875 1 11.44100906 -1 0.047396869 2.28E-14 4.061041729 0.662243634 0.166069373 239.3348866 0.867339557 18.46013049 73.02730142 0.1 1 4.061041729 EQPGEEYS(ph)EEEESVLK ddPTM_HeLa_Curcumin_4h_R1 2 EQPGEEYSEEEESVLK 16 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 0 EQPGEEY(0.003)S(0.997)EEEES(0.001)VLK;EQPGEEYS(0.994)EEEES(0.006)VLK ; 157.73 0.00028767 36110000 4813.7 3713.9 4229.9 4917 4968.2 5119 4061.2 2296.5 4996.3 4629.1 TRUE FALSE FALSE 4432.690566 4034.912967 4386.663815 4896.654757 4908.95746 4057.261697 4175.146342 2996.692278 4448.21839 4789.96088 0.925412686 0.842368668 0.915803683 1.022274478 1.024842913 0.847034412 0.871645186 0.625619364 0.92865443 1 12.22579816 -3.837560029 1.122103165 0.957025192 0.127450165 0.715250512 0.059533245 1.543746037 0.822791371 0.009593153 1.898704714 0.000145358 3.837560029 -0.829575026 EQPPAETPTDAAVLTSPPAPAPPVT(ph)PSKPMAGTTDREEATR ddPTM_HeLa_Curcumin_4h_R1 1 EQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATR 41 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 EQPPAET(0.001)PT(0.002)DAAVLT(0.163)S(0.163)PPAPAPPVT(0.425)PS(0.163)KPMAGT(0.039)T(0.039)DREEAT(0.004)R 46.759 0.0024257 30794000 1319.4 1360.8 1587.9 1890 1543.3 1934.1 492.97 738.11 1573.9 1427 TRUE FALSE FALSE 1214.968098 1478.421488 1646.748971 1882.179681 1524.897155 1532.945858 506.8014114 963.1563412 1401.247108 1476.588144 0.822821247 1.001241609 1.115239194 1.274681561 1.032716646 1.038167525 0.343224625 0.65228503 0.948976269 1 10.52805176 -4.768196372 24.99999854 0.975371468 0.497754792 0.693613804 0.137617152 71.14194328 263220.3196 0.022354148 0.069319056 1.71E-05 4.768196372 -0.477616676 EQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEAT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 EQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATR 41 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 EQPPAETPTDAAVLT(0.006)S(0.006)PPAPAPPVT(0.197)PS(0.197)KPMAGT(0.197)T(0.178)DREEAT(0.218)R 49.806 0.0014261 11447000 1603.9 1111.5 1351.7 1350.7 1566.8 1727.7 1436.2 954 1450.4 1347.7 TRUE FALSE FALSE 1476.949623 1207.573107 1401.795191 1345.111161 1548.116933 1369.355545 1476.495907 1244.870208 1291.294749 1394.532475 1.0591002 0.865934017 1.005207994 0.964560658 1.110133297 0.981945971 1.058774846 0.892679253 0.925969651 1 10.44556582 EQQEAIEHIDEVQNEIDR ddPTM_HeLa_Curcumin_4h_R1 2 EQQEAIEHIDEVQNEIDR 18 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 0 ; ; 209.19 1.40E-12 11664100 25351.4 22884.9 22313.2 23906 25052.8 32786 26511.6 30471 25522.9 22268.7 FALSE FALSE TRUE 23344.80994 24862.96878 23140.14682 23807.08331 24754.06172 25985.81403 27255.44414 39761.46763 22723.10173 23042.53567 1.013118099 1.079003159 1.004236129 1.03317984 1.07427681 1.127732399 1.182831809 1.725568236 0.986137205 1 14.49201186 -1.287871855 0.902333645 1.015232288 199.9999636 0.973108142 0.034363311 49.73354304 0.18588365 0.005143957 20271.05071 0.051538069 1.287871855 198.9847313 EQQSNIAVFQGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EQQSNIAVFQGKK 13 1 Q8NEF9 Q8NEF9 SRFBP1 Serum response factor-binding protein 1 0 1 ; EQQSNIAVFQGK(1)K;EQQSNIAVFQGK(1)K 299.29 7.99E-115 14875200 7967.9 6475.9 6588.4 6628.3 5953 9577 7121.1 8420 7362.6 6733.5 FALSE TRUE FALSE 7337.232307 7035.64794 6832.5719 6600.873851 5882.014363 7590.622245 7320.898901 10987.21924 6554.9412 6967.488624 1.053066995 1.00978248 0.980636248 0.947382078 0.844208678 1.089434466 1.050722763 1.576926757 0.940789652 1 12.76642303 -4.225808843 3.096373383 1.007024402 1.692694126 0.873654777 0.066778213 0.113190157 1.499351863 0.009317069 0.196211707 5.95E-05 4.225808843 0.685669723 EQQSWVIS(ph)PPQPSPQK ddPTM_HeLa_Curcumin_4h_R1 1 EQQSWVISPPQPSPQK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 0 EQQS(0.01)WVIS(0.989)PPQPSPQK 148.52 0.00035688 9713400 1908.5 1412.5 1783.9 1773.8 1687.6 1866.8 761.28 1261.6 1934.3 1590.8 TRUE FALSE FALSE 1757.440211 1534.590206 1850.012903 1766.460486 1667.476472 1479.604637 782.6394679 1646.256032 1722.112129 1646.080182 1.067651643 0.932269414 1.123889908 1.073131495 1.012998328 0.89886547 0.475456467 1.00010683 1.046189699 1 10.6848189 -4.995263655 24.94813374 1.03121763 0.725126411 0.470388675 0.126863339 69.86407211 367989.2333 0.015429347 0.046045739 1.01E-05 4.995263655 -0.30609122 EQQSWVISPPQPS(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 1 EQQSWVISPPQPSPQK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 0 EQQSWVIS(0.038)PPQPS(0.962)PQK 188.96 4.72E-07 8412100 6979.1 6863 6998.6 6727.3 6872.6 8296 6344.5 4076.2 7988 6311.7 TRUE FALSE FALSE 6426.696871 7456.207139 7257.974273 6699.464215 6790.648734 6575.316085 6522.509595 5319.014615 7111.736385 6531.031105 0.984024845 1.141658494 1.111306034 1.025789666 1.0397514 1.006780703 0.998695227 0.814421878 1.088914793 1 12.67309506 -4.248287895 3.424806013 1.017754441 0.785440858 0.570536714 0.055946846 0.209032524 4.020861675 0.008238501 0.12805664 5.65E-05 4.248287895 -0.232313583 SSRS(ph)SPELTR ddPTM_HeLa_Curcumin_4h_R1 1 SSRSSPELTR 10 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.009)S(0.009)RS(0.811)S(0.143)PELT(0.028)R 69.846 0.019411 218370000 544.01 321.59 371.53 449.8 243.63 460.91 210.99 43.422 439.31 402.12 TRUE FALSE FALSE 500.9510345 349.3868066 385.2992286 447.9388468 240.7248714 365.3120705 216.9098115 56.66116791 391.1187921 416.0936401 1.203938215 0.839683122 0.925991632 1.07653375 0.57853533 0.877956391 0.521300473 0.136174078 0.939977819 1 8.700764427 -4.684692323 0.618794308 1.078983526 4.56E-14 0.718475421 0.158213361 0.813834424 0.288613395 0.029153236 0.560980164 2.07E-05 4.684692323 -1.078983526 down EQSEVSVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 EQSEVSVSPR 10 0 Q7L4I2;E9PI52 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 0 EQSEVSVS(1)PR;EQSEVSVS(1)PR;EQSEVS(0.01)VS(0.99)PR ;; 176.32 0.00038192 1383912000 8405.07 6931.2 6493.23 7087.78 7507.2 9095.5 6623.58 7270.7 7823.6 6774.9 TRUE FALSE FALSE 7739.799841 7530.302043 6733.874816 7058.452644 7417.681543 7208.990773 6809.419828 9487.50296 6965.370654 7010.327271 1.10405685 1.074172682 0.960564972 1.006864925 1.05810774 1.028338692 0.971341218 1.353360919 0.993587087 1 12.77526608 -4.253935592 24.99119336 1.038320716 1.35336107 0.820586351 0.045922792 332.1141156 1106071.717 0.007256517 0.102764387 5.57E-05 4.253935592 0.315040354 EQSIVEK(ac)FRSR ddPTM_HeLa_Curcumin_4h_R1 1 EQSIVEKFRSR 11 2 Q86U44;H0YFV6 Q86U44 METTL3 N6-adenosine-methyltransferase 70 kDa subunit 0 1 EQSIVEK(1)FRSR 69.216 0.01898 1567200 315.25 189.76 209.51 410.73 242.06 385.83 276.49 198.18 312.19 254.4 FALSE TRUE FALSE 290.2976298 206.1620088 217.2746249 409.0305081 239.1735926 305.8045088 284.2475653 258.6041697 277.9435381 263.2403811 1.102785328 0.78317015 0.825384859 1.553828886 0.908574861 1.161693003 1.079802286 0.982387917 1.055854489 1 8.040237005 EQSQLTATQTR ddPTM_HeLa_Curcumin_4h_R1 2 EQSQLTATQTR 11 0 Q6P2Q9 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 0 ; ; 139.86 7.97E-05 1175370 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 EQSSDLTPSGDVS(ph)PVKPLSR ddPTM_HeLa_Curcumin_4h_R1 2 EQSSDLTPSGDVSPVKPLSR 20 1 Q8WYQ5-3;Q8WYQ5 Q8WYQ5-3 DGCR8 Microprocessor complex subunit DGCR8 1 0 EQSSDLTPS(0.001)GDVS(0.521)PVKPLS(0.478)R;EQSSDLTPS(0.005)GDVS(0.99)PVKPLS(0.005)R ; 132.94 4.18E-05 219959000 7284.3 5663.1 6846.7 6406 7228.2 8343.6 5813.2 4449.6 6407.3 5489.3 TRUE FALSE FALSE 6707.739969 6152.59313 7100.444725 6379.493669 7142.008436 6613.043308 5976.302747 5806.262557 5704.43522 5680.052766 1.180929165 1.083192953 1.250066684 1.12313986 1.25738417 1.164257372 1.052156202 1.022219827 1.004292646 1 12.47168862 -9.350763365 0.965424363 0.995994619 1.146897739 0.364422766 0.073237064 0.533776921 0.852085954 0.058052805 0.013632015 4.46E-10 9.350763365 0.15090312 EQSSEAAETGVS(ph)ENEENPVR ddPTM_HeLa_Curcumin_4h_R1 1 EQSSEAAETGVSENEENPVR 20 0 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 0 EQSSEAAET(0.099)GVS(0.901)ENEENPVR 159.06 1.57E-11 0 1004.9 909.72 1008.4 1070.3 921.66 1088.9 702.66 756.79 1069.5 972.58 TRUE FALSE FALSE 925.3611046 988.3521432 1045.772191 1065.871382 910.6698065 863.0498656 722.3747485 987.5317872 952.1785258 1006.377083 0.919497394 0.982089279 1.039145475 1.059117304 0.90489919 0.857581001 0.717797296 0.981274121 0.946144882 1 9.974955259 -5.466121414 3.789445531 0.975540231 0.840770039 0.422564967 0.07166596 0.174163028 4.9973066 0.010407871 0.023826319 3.42E-06 5.466121414 -0.134770192 KSS(ph)ADTEFSDECTTAER ddPTM_HeLa_Curcumin_4h_R1 1 KSSADTEFSDECTTAER 17 1 Q9H6S0 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 1 0 KS(0.182)S(0.818)ADTEFSDECTTAER 88.57 0.0023472 27017000 800.74 683.68 531.93 650.73 863 876.34 894.92 1387.1 962.01 865.68 TRUE FALSE FALSE 737.3605841 742.7742528 551.6437937 648.0374517 852.7092886 694.5772056 920.0290466 1810.020405 856.4799098 895.7623156 0.823165444 0.829209088 0.615837242 0.723447996 0.951936997 0.775403468 1.027090592 2.020648082 0.956146396 1 9.806972164 -4.265234552 3.400549277 0.868542744 2.164360434 0.905444824 0.113980108 0.075143075 1.453247834 0.018337133 0.25041918 5.43E-05 4.265234552 1.295817691 up EQTLS(ph)PTITSGLHNIAR ddPTM_HeLa_Curcumin_4h_R1 1 EQTLSPTITSGLHNIAR 17 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0Y8W8 D6REX3 SEC31A Protein transport protein Sec31A 1 0 EQT(0.105)LS(0.556)PT(0.337)IT(0.002)SGLHNIAR 92.427 0.0017063 7960000 2372.9 2026 1964 2191.2 3183.9 4329 2516.1 2116.6 3042.2 2441 TRUE FALSE FALSE 2185.082461 2201.118412 2036.787568 2182.133395 3145.934072 3431.116602 2586.694994 2761.941596 2708.478271 2525.824568 0.865096685 0.871445484 0.806385207 0.863929119 1.245507749 1.358414454 1.02409923 1.093481167 1.072314485 1 11.30253872 -5.763185002 24.99999961 0.914059376 1.181930125 0.590759383 0.108937246 24.81397801 355382.4172 0.016104244 0.030329099 1.73E-06 5.763185002 0.267870749 EQTLSPT(ph)ITSGLHNIAR ddPTM_HeLa_Curcumin_4h_R1 2 EQTLSPTITSGLHNIAR 17 0 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;H7BXG7;O94979-7;O94979-6;O94979-10;O94979-4;H0Y8W8 D6REX3 SEC31A Protein transport protein Sec31A 1 0 EQT(0.017)LS(0.432)PT(0.523)IT(0.029)SGLHNIAR;EQT(0.003)LS(0.082)PT(0.862)IT(0.052)SGLHNIAR ; 196.31 2.54E-07 44255700 3768.7 3282.3 3371.1 2863.8 4216.6 6760.6 3758.2 3258.6 4598.8 2948.1 TRUE FALSE FALSE 3470.403418 3566.007386 3496.035932 2851.950354 4166.319799 5358.375352 3863.644977 4252.132139 4094.323146 3050.546256 1.137633436 1.168973386 1.146036034 0.93489825 1.365761883 1.756529783 1.266542007 1.393892039 1.34216065 1 11.57485189 -5.618171213 5.788938117 1.074519742 1.468652007 0.501199077 0.156531321 0.093248135 4.663153026 0.019180323 0.038773059 2.41E-06 5.618171213 0.394132265 EQVANS(ph)AFVER ddPTM_HeLa_Curcumin_4h_R1 2 EQVANSAFVER 11 0 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 1 0 EQVANS(1)AFVER;EQVANS(1)AFVER ; 124.16 0.0036572 34411000 3578.4 3255.1 3532.7 3738.4 3576.6 3958 2913.4 2475.2 4312.4 3048.1 TRUE FALSE FALSE 3295.165864 3536.45634 3663.62497 3722.931491 3533.951381 3137.066184 2995.142163 3229.877086 3839.340509 3154.021248 1.044750686 1.121253175 1.161572698 1.180376161 1.120458964 0.994624303 0.949626501 1.024050516 1.217284288 1 11.62297666 -5.037769412 19.65035702 1.058051598 0.983160317 0.117466713 0.080788311 62.20128502 32362.30542 0.011335059 0.028928426 9.17E-06 5.037769412 -0.074891281 EQVANSAFVER ddPTM_HeLa_Curcumin_4h_R1 3 EQVANSAFVER 11 0 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 0 ;; ;; 211.46 5.20E-23 66089200 7420.2 6067.5 5748.1 6289.3 6226.9 6377.9 5531.1 6047.5 6239 5681.3 FALSE FALSE TRUE 6832.88334 6591.947664 5961.129643 6263.276543 6152.648284 5055.051646 5686.28778 7891.354911 5554.597309 5878.724752 1.16230707 1.121322726 1.014017477 1.065414151 1.04659574 0.859889153 0.967265524 1.342358291 0.944864327 1 12.52128752 -6.748593889 24.80109209 1.082137389 1.037535714 0 0.128210188 755.7407261 1459123.976 0.019903635 0.028043021 1.78E-07 6.748593889 -0.044601675 EQVEPTPEDEDDDIELR ddPTM_HeLa_Curcumin_4h_R1 2 EQVEPTPEDEDDDIELR 17 0 A0A087WZG9;B4DSP0;A0A087WXK2;A0A087WUL4;A0A087WX23;Q86TG7-2;Q86TG7 A0A087WZG9 PEG10 Retrotransposon-derived protein PEG10 0 0 ; ; 207.08 6.92E-10 29521000 6909.6 6267 6708 7065.3 6762.3 7818.8 6183.1 4709.9 6585.9 6223.3 FALSE FALSE TRUE 6362.697869 6808.691555 6956.604381 7036.065661 6681.663989 6197.092744 6356.581145 6145.926828 5863.443247 6439.559212 0.988064192 1.05732261 1.080292013 1.092631565 1.037596483 0.96234735 0.987114325 0.954401788 0.910534876 1 12.65274622 -5.24978604 24.07573196 1.015748647 0.969870466 0.195921175 0.049960151 646.1155329 1334863.733 0.006609984 0.016669493 5.63E-06 5.24978604 -0.045878181 EQWIQDAEECDR ddPTM_HeLa_Curcumin_4h_R1 2 EQWIQDAEECDR 12 0 O94906-2;O94906 O94906-2 PRPF6 Pre-mRNA-processing factor 6 0 0 ; ; 247.13 5.84E-26 31786000 4986.1 3957.4 4522.4 5698 5462 4112.4 3826.6 3066.9 5132.2 4949.8 FALSE FALSE TRUE 4591.444924 4299.460022 4690.004122 5674.423186 5396.869217 3259.441884 3933.964097 4001.983692 4569.2105 5121.805182 0.896450521 0.83944232 0.91569358 1.107895163 1.05370451 0.63638537 0.768081557 0.781361951 0.892109391 1 12.32243666 -5.261313076 24.99999996 0.956718215 0.732556817 0.610947071 0.08382732 6.256440604 1238194.626 0.012761831 0.030396271 5.48E-06 5.261313076 -0.224161398 EQYVPPRS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 EQYVPPRSPK 10 1 X6RLN4;Q71RC2-2;Q71RC2-6;Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4 X6RLN4 LARP4 La-related protein 4 1 0 EQYVPPRS(1)PK 76.728 0.015665 31019000 6294 5588.6 5716 5729.3 6811 6431.7 5595.6 5653.2 5698.7 5441.1 TRUE FALSE FALSE 5795.823259 6071.653682 5927.839988 5705.593675 6729.783273 5097.69292 5752.597476 7376.834656 5073.566867 5630.17782 1.029420996 1.078412419 1.052869053 1.013394933 1.195305635 0.905423076 1.02174348 1.310231203 0.901137944 1 12.45896477 -4.260880497 24.79769505 1.026273811 1.3102313 0.541633462 0.079465711 20.10558583 891832.3138 0.008884801 0.070338407 5.48E-05 4.260880497 0.283957489 ERALS(ph)PGLEESGLGLLAR ddPTM_HeLa_Curcumin_4h_R1 1 ERALSPGLEESGLGLLAR 18 1 H9KVB4;O15417-2;O15417 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 0 ERALS(0.999)PGLEES(0.001)GLGLLAR 55.634 0.015993 1879800 747.76 562.79 896.22 861.64 786.78 1158.7 710.73 625 1080.6 973.06 TRUE FALSE FALSE 688.574007 611.4350599 929.4347016 858.074762 777.3981624 918.3725588 730.671171 815.5596229 962.0608835 1006.873763 0.683873225 0.607260893 0.923089603 0.852216826 0.772090992 0.912102979 0.725682998 0.809991931 0.955493051 1 9.975667101 -9.475040344 1.244204894 0.99871936 0.777593254 0.397750453 0.093709619 0.358033534 1.000614707 0.066275455 0.016671192 3.35E-10 9.475040344 -0.221126106 ERAS(ph)SPPDRIDIFGR ddPTM_HeLa_Curcumin_4h_R1 1 ERASSPPDRIDIFGR 15 2 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 1 0 ERAS(0.5)S(0.5)PPDRIDIFGR 50.659 0.018253 7739900 171.18 138.55 131.84 228.07 194.51 249.17 244.92 54.732 261.54 237.67 TRUE FALSE FALSE 157.6309224 150.5256446 136.7261064 227.1263068 192.1905953 197.4893333 251.791796 71.41953484 232.8497163 245.9290148 0.640961061 0.612069482 0.555957606 0.923544166 0.781488087 0.803033889 1.023839323 0.290407112 0.946816774 1 7.942098145 -9.344912509 1.076195756 0.999487106 0.715040779 0.233502016 0.193667091 0.584774719 1.215447366 0.124463355 0.032825363 4.52E-10 9.344912509 -0.284446328 ERDFTSLENTVEER ddPTM_HeLa_Curcumin_4h_R1 1 ERDFTSLENTVEER 14 1 Q07065 Q07065 CKAP4 Cytoskeleton-associated protein 4 0 0 94.532 0.0066389 3241800 339.39 515.36 318.55 229.94 400.16 511.46 294.42 241.37 593.68 392.84 FALSE FALSE TRUE 312.5269234 559.905422 330.3557432 228.9885692 395.3883534 405.3774307 302.6806328 314.9626019 528.5547893 406.4911608 0.768840638 1.377411063 0.812700927 0.563329763 0.972686227 0.997260137 0.744617994 0.774832597 1.300286059 1 8.667080171 ERDHS(ph)PTPSVFNSDEER ddPTM_HeLa_Curcumin_4h_R1 3 ERDHSPTPSVFNSDEER 17 1 Q6UN15-5;Q6UN15;Q6UN15-3 Q6UN15-5 FIP1L1 Pre-mRNA 3-end-processing factor FIP1 1 0 ERDHS(0.99)PT(0.01)PS(0.001)VFNSDEER;ERDHS(0.774)PT(0.124)PS(0.102)VFNSDEER;ERDHS(0.866)PT(0.117)PS(0.017)VFNSDEER ;; 81.788 0.0032141 72686000 6011.6 5325.7 5524.2 5331.4 6628.7 7220.4 4766.9 3284 6219.6 5431.5 TRUE FALSE FALSE 5535.775517 5786.029777 5728.931712 5309.340079 6549.657082 5722.807649 4900.646385 4285.276482 5537.325441 5620.244221 0.984970635 1.029497927 1.019338571 0.944681382 1.165368768 1.018248927 0.871963244 0.762471578 0.98524641 1 12.45641711 -4.562879738 3.119326045 1.007396585 0.773540235 0.688536512 0.055942458 0.110254116 2.052479562 0.007765196 0.044409345 2.74E-05 4.562879738 -0.23385635 ERDS(ph)ELSDTDSGCCLGQSESDK ddPTM_HeLa_Curcumin_4h_R1 2 ERDSELSDTDSGCCLGQSESDK 22 1 A0A087WVR3;A0A087WTW0;Q96T88;Q96T88-2 A0A087WVR3 UHRF1 E3 ubiquitin-protein ligase UHRF1 1 0 ERDS(0.409)ELS(0.409)DT(0.04)DS(0.142)GCCLGQSESDK;ERDS(0.482)ELS(0.365)DT(0.133)DS(0.021)GCCLGQSESDK ; 85.814 0.00024633 67946000 8430.5 7068.1 7501.2 7952 8875.2 9084.3 6070.5 3586.1 7556.3 6470.1 TRUE FALSE FALSE 7763.217029 7679.035069 7779.201071 7919.096731 8769.369037 7200.113779 6240.821892 4679.485382 6727.392795 6694.935493 1.15956562 1.146991644 1.161953103 1.182848847 1.309851162 1.075456782 0.932170579 0.698958995 1.004848038 1 12.70885444 -4.448502866 2.212381248 1.112904473 0.670542947 0.710132283 0.08655197 0.218120386 1.594808235 0.014430833 0.160478625 3.56E-05 4.448502866 -0.442361526 SSQLDSGVPS(ph)SPGGR ddPTM_HeLa_Curcumin_4h_R1 1 SSQLDSGVPSSPGGR 15 0 I3L4X5;Q70CQ4 I3L4X5 USP31 Ubiquitin carboxyl-terminal hydrolase 31 1 0 SSQLDS(0.004)GVPS(0.928)S(0.068)PGGR 160.93 0.00030084 9431200 2302.4 1888.6 2118.6 2649.7 2148.9 2257.7 1507.3 824.66 2829.6 2143.1 TRUE FALSE FALSE 2120.162611 2051.842169 2197.11718 2638.736243 2123.275771 1789.42757 1549.590781 1076.095038 2519.199959 2217.572565 0.956073611 0.92526495 0.990775776 1.189921036 0.957477471 0.806930785 0.698777936 0.485258095 1.136016922 1 11.1147656 -4.683107734 1.435050231 0.990207006 0.465281561 0.807575813 0.085971178 0.180658441 0.550365451 0.011182884 0.108483969 2.07E-05 4.683107734 -0.524925446 down ERDSASFNPELLTHILDGS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 1 ERDSASFNPELLTHILDGSPEK 22 1 I3L2U4;K7ELT1;I3L0T4;Q15067-2;Q15067 I3L2U4 ACOX1 Peroxisomal acyl-coenzyme A oxidase 1 1 0 ERDSASFNPELLT(0.013)HILDGS(0.987)PEK 91.541 0.0003753 0 598.35 457.22 687.45 676.19 563.67 491.65 352.94 489.65 703.95 585.96 TRUE FALSE FALSE 550.9899661 496.7400595 712.9275017 673.3921049 556.9486034 389.676248 362.8425465 638.9420309 626.7284462 606.3220664 0.908741404 0.819267658 1.175823117 1.110617842 0.918568916 0.642688547 0.598432032 1.053799732 1.033656007 1 9.243940518 -5.433314118 6.190188038 0.973868293 0.750373149 0.335372956 0.147918337 0.211817409 12.01079464 0.020661559 0.046493737 3.69E-06 5.433314118 -0.223495144 ERDTSPDKGELVS(ph)DEEEDT ddPTM_HeLa_Curcumin_4h_R1 1 ERDTSPDKGELVSDEEEDT 19 2 Q9UPU7 Q9UPU7 TBC1D2B TBC1 domain family member 2B 1 0 ERDTSPDKGELVS(0.931)DEEEDT(0.069) 58.755 0.017856 47741000 3789.5 3319.1 2838.3 3137.1 3141.1 3554 2456.3 1749.3 3559.5 3333.9 TRUE FALSE FALSE 3489.557076 3605.988214 2943.489895 3124.119511 3103.644434 2816.860338 2525.217167 2282.653517 3169.031755 3449.752777 1.011538305 1.045288879 0.853246619 0.905606782 0.899671552 0.81653977 0.731999459 0.661686116 0.918625757 1 11.75227726 -4.392161292 0.440854265 1.01222292 0.427161688 0.814788172 0.050127531 0.963032778 0.135732307 0.0101167 0.287686302 4.05E-05 4.392161292 -0.585061232 ERDVIMR ddPTM_HeLa_Curcumin_4h_R1 1 ERDVIMR 7 1 P60842;J3KT12;P60842-2;J3KSZ0;E7EQG2;Q14240;Q14240-2;J3QL52 P60842 EIF4A1;EIF4A2 "Eukaryotic initiation factor 4A-I;Eukaryotic initiation factor 4A-II;Eukaryotic initiation factor 4A-II, N-terminally processed" 0 0 101.33 0.016322 2758900 1603.9 1488.9 1778.7 1754.7 1304.2 1480.7 1440.3 1405.6 1588.1 1592.1 FALSE FALSE TRUE 1476.949623 1617.593882 1844.620187 1747.439516 1288.648267 1173.586129 1480.710942 1834.160969 1413.889403 1647.425356 0.896519904 0.981892063 1.119698795 1.060709373 0.782219517 0.712375905 0.898803054 1.113349969 0.858241861 1 10.68599738 -5.760482747 24.99997677 0.973455202 0.866530318 0.161874088 0.119080999 38.31426751 1001224.797 0.017801153 0.034031226 1.74E-06 5.760482747 -0.106924884 EREAANEAGDS(ph)S(ph)QDEAEDDVK ddPTM_HeLa_Curcumin_4h_R1 1 EREAANEAGDSSQDEAEDDVK 21 1 A0A0C4DH01;Q9NVU0-3;Q9NVU0-2;Q9NVU0-5;Q9NVU0-4;Q9NVU0 A0A0C4DH01 POLR3E DNA-directed RNA polymerase III subunit RPC5 2 0 EREAANEAGDS(1)S(1)QDEAEDDVK 86.189 0.00055569 15202000 2638.1 2099.3 1716.2 2280.1 1990.6 2207.9 1695.7 1468.7 2335.6 1955.7 TRUE FALSE FALSE 2429.291601 2280.754138 1779.803882 2270.66555 1966.863395 1749.956652 1743.276778 1916.499869 2079.390523 2023.660429 1.200444287 1.127043898 0.879497299 1.122058581 0.971933515 0.864748169 0.861447283 0.947046175 1.027539252 1 10.98275151 -5.710075468 1.051304955 1.091342659 0.880294141 0.381663723 0.088817541 0.411992098 0.873918495 0.017124575 0.054265372 1.95E-06 5.710075468 -0.211048518 EREAELGAR ddPTM_HeLa_Curcumin_4h_R1 1 EREAELGAR 9 1 P11940;P11940-2;E7EQV3;A0A087WTT1;E7ERJ7;H0YAR2;Q9H361;H0YBN4;Q4VXU2-2;Q4VXU2 P11940 PABPC1;PABPC3;PABPC1L Polyadenylate-binding protein 1;Polyadenylate-binding protein;Polyadenylate-binding protein 3;Polyadenylate-binding protein 1-like 0 0 83.948 0.016478 597070 361.31 317.56 377.73 502.35 205.91 454.64 328.43 247.24 550.01 300.85 FALSE FALSE TRUE 332.7119322 345.0084714 391.7290061 500.2714088 203.4546577 360.3425392 337.6448619 322.6223378 489.6752791 311.3045151 1.068766806 1.10826684 1.25834669 1.607016232 0.653555114 1.157524294 1.0846128 1.036356115 1.572978403 1 8.282182691 -1.001036345 8.761998458 1.07537748 0.00045905 0 0.275103892 0 0 0.028326329 0 0.099761657 1.001036345 -1.07491843 ERECS(ph)PS(ph)SPLPPLPEDEEGSEVTNSK ddPTM_HeLa_Curcumin_4h_R1 1 ERECSPSSPLPPLPEDEEGSEVTNSK 26 1 Q96GY3 Q96GY3 LIN37 Protein lin-37 homolog 2 0 ERECS(0.77)PS(0.717)S(0.513)PLPPLPEDEEGSEVTNSK 65.495 0.0008533 19257000 3192.4 2792 2715 3604.6 3062.1 3451.4 2727.9 2028.9 3359.6 2548.3 TRUE FALSE FALSE 2939.718171 3033.328039 2815.620288 3589.68512 3025.586457 2735.540735 2804.437532 2647.50227 2991.060285 2636.853235 1.114858473 1.150359071 1.067795602 1.361351884 1.147423155 1.037426239 1.063554655 1.004038539 1.134329452 1 11.36460156 -3.088107411 10.86284469 1.084237665 1.108876969 0 0.102479696 0 0 0.014464502 0 0.00081638 3.088107411 0.024639304 ERECS(ph)PSS(ph)PLPPLPEDEEGSEVTNSK ddPTM_HeLa_Curcumin_4h_R1 1 ERECSPSSPLPPLPEDEEGSEVTNSK 26 1 Q96GY3 Q96GY3 LIN37 Protein lin-37 homolog 2 0 ERECS(0.919)PS(0.506)S(0.576)PLPPLPEDEEGSEVTNSK 91.779 8.57E-06 16679000 692.99 429.68 411 676.57 479.97 683.57 308.19 376.45 559.38 337.07 TRUE FALSE FALSE 638.1391103 466.8196246 426.2320216 673.7705326 474.2466712 541.7898766 316.8369819 491.227872 498.0174135 348.7831574 1.829615613 1.338423644 1.222054484 1.931774853 1.359717811 1.553371673 0.908406771 1.408404797 1.427871166 1 8.446186564 -4.778875668 24.99120467 1.428590698 1.15840556 0.146835602 0.281745651 411.1580103 589309.4066 0.049446909 0.148832727 1.66E-05 4.778875668 -0.270185137 ERECS(ph)PSSPLPPLPEDEEGSEVTNSK ddPTM_HeLa_Curcumin_4h_R1 1 ERECSPSSPLPPLPEDEEGSEVTNSK 26 1 Q96GY3 Q96GY3 LIN37 Protein lin-37 homolog 1 0 ERECS(0.902)PS(0.096)S(0.002)PLPPLPEDEEGSEVTNSK 58.626 0.0021675 4017100 426.38 432.42 349.57 502.37 362.79 477.25 425.97 222.56 310.1 503.73 TRUE FALSE FALSE 392.6315731 469.796458 362.5253717 500.2913261 358.4639662 378.2629703 437.9215718 290.4175195 276.0828058 521.23458 0.753272304 0.901314832 0.695512895 0.959819907 0.687720999 0.725705824 0.840162162 0.557172395 0.529670932 1 9.025788989 -13.52287875 0.175695526 1.967670851 0.705598926 0 0.179584329 38.06546448 0.430772104 12.66612499 0.142977043 3.00E-14 13.52287875 -1.262071924 ERECSPS(ph)SPLPPLPEDEEGSEVTNSK ddPTM_HeLa_Curcumin_4h_R1 2 ERECSPSSPLPPLPEDEEGSEVTNSK 26 1 Q96GY3 Q96GY3 LIN37 Protein lin-37 homolog 1 0 ERECS(0.123)PS(0.533)S(0.345)PLPPLPEDEEGSEVTNSK;ERECS(0.224)PS(0.388)S(0.388)PLPPLPEDEEGSEVTNSK ; 124.39 1.16E-08 110948000 4618 3187.3 3762 3753.3 3466.3 4386.9 3214.5 2208.51 4327.4 4163.4 TRUE FALSE FALSE 4252.480427 3462.79601 3901.423029 3737.769839 3424.966636 3477.007489 3304.690219 2881.874532 3852.695047 4308.07784 0.987094613 0.803791421 0.905606438 0.867618919 0.795010388 0.807090219 0.767091576 0.668946718 0.894295598 1 12.0728286 -5.098291211 0.284217239 1.023383829 0.548879882 0.656247572 0.056636114 1.441845849 0.129358503 0.027108687 0.229083681 7.97E-06 5.098291211 -0.474503947 EREDES(ph)EDESDILEESPCGR ddPTM_HeLa_Curcumin_4h_R1 2 EREDESEDESDILEESPCGR 20 1 Q9NSY0 Q9NSY0 NRBP2 Nuclear receptor-binding protein 2 1 0 EREDES(0.912)EDES(0.088)DILEESPCGR;EREDES(0.97)EDES(0.029)DILEESPCGR ; 93.392 0.00041143 52982000 1909.09 1675.68 1550.91 1963.07 2036.6 2158.32 1828.41 1149.6 2230.29 1980.32 TRUE FALSE FALSE 1757.983512 1820.518313 1608.388089 1954.947336 2012.314875 1710.660103 1879.710264 1500.107748 1985.632767 2049.135973 0.857914524 0.888432167 0.784910377 0.954034951 0.982030915 0.8348202 0.917318464 0.732068427 0.969009765 1 11.0008 -9.258521733 0.825262995 1.006189888 0.872829296 0.290813734 0.071298185 0.671776109 0.761978405 0.058393688 0.013378796 5.51E-10 9.258521733 -0.133360592 EREDS(ph)GDAEAHAFK ddPTM_HeLa_Curcumin_4h_R1 1 EREDSGDAEAHAFK 14 1 Q9NPI1;Q9NPI1-2 Q9NPI1 BRD7 Bromodomain-containing protein 7 1 0 EREDS(1)GDAEAHAFK 69.612 0.014702 13352000 3155.5 2935.7 2689.9 3386.8 3469.4 3581.2 2412.5 2696.4 3655.4 3594.4 TRUE FALSE FALSE 2905.738845 3189.448827 2789.59006 3372.786319 3428.029671 2838.418752 2480.188257 3518.519947 3254.411765 3719.305132 0.781258526 0.857538899 0.750029901 0.906832378 0.921685516 0.763158346 0.666841834 0.946015404 0.875005317 1 11.8608174 -9.341922667 0.917872453 1.007108506 0.818737194 0.144762492 0.090835672 0.505360754 0.715655072 0.066948349 0.015140038 4.55E-10 9.341922667 -0.188371311 EREEFYR ddPTM_HeLa_Curcumin_4h_R1 1 EREEFYR 7 1 G3V2V6;H0YJH8;G3V2S6;Q9Y5K8 G3V2V6 ATP6V1D V-type proton ATPase subunit D 0 0 116.88 0.011781 6121000 1815 1210.2 1309.6 1531 1383.7 1478.8 1329.9 1202.8 1186 1214.9 FALSE FALSE TRUE 1671.340835 1314.804295 1358.134928 1524.665128 1367.200281 1172.08021 1367.213415 1569.528183 1055.898767 1257.117685 1.329502286 1.045887996 1.080356235 1.212826091 1.087567455 0.9323552 1.087577903 1.248513327 0.839936293 1 10.295904 -5.554051938 23.00044747 1.147497842 1.076069958 0 0.148019848 213.2463758 157338.0458 0.020966845 0.041934355 2.79E-06 5.554051938 -0.071427883 EREES(ph)EDELEEANGNNPIDIEVDQNK ddPTM_HeLa_Curcumin_4h_R1 3 EREESEDELEEANGNNPIDIEVDQNK 26 1 Q9UKL0 Q9UKL0 RCOR1 REST corepressor 1 1 0 EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK;EREES(1)EDELEEANGNNPIDIEVDQNK ;; 159.89 8.95E-10 370447200 8404.6 7806.5 8969.2 8622.5 9974.4 10668.1 8390.4 7220.8 8974.6 6976.6 TRUE FALSE FALSE 7739.367042 8481.259075 9301.606442 8586.82238 9855.461794 8455.415806 8625.812042 9422.38868 7990.108833 7219.036331 1.072077586 1.174846432 1.288483118 1.18946934 1.365204626 1.171266554 1.194870291 1.305214193 1.106811002 1 12.81759055 -7.254429316 1.564396754 1.025968682 1.250163625 0.644849225 0.062814929 0.127022237 0.591146391 0.010737322 0.012775511 5.57E-08 7.254429316 0.224194944 EREES(ph)EDELEEANGNNPIDIEVDQNKESK ddPTM_HeLa_Curcumin_4h_R1 2 EREESEDELEEANGNNPIDIEVDQNKESK 29 2 Q9UKL0 Q9UKL0 RCOR1 REST corepressor 1 1 0 EREES(1)EDELEEANGNNPIDIEVDQNKESK;EREES(1)EDELEEANGNNPIDIEVDQNKESK ; 141.19 3.34E-13 188674000 8626.7 6155.5 7172.3 8007.3 6835.3 9213.1 6741.2 5603.8 8090.9 7259.4 TRUE FALSE FALSE 7943.887592 6687.553992 7438.111747 7974.167914 6753.793512 7302.199207 6930.339929 7312.372823 7203.348512 7511.66361 1.057540381 0.890289334 0.990208313 1.061571488 0.899107556 0.972114779 0.922610528 0.973469155 0.958955151 1 12.87491674 -6.547066046 0.716206447 1.023794503 0.94871101 0 0.057143728 0.75712351 0.779883955 0.012301956 0.024313824 2.84E-07 6.547066046 -0.075083493 EREES(ph)EDELEEANGNNPIDIEVDQNKESKK ddPTM_HeLa_Curcumin_4h_R1 1 EREESEDELEEANGNNPIDIEVDQNKESKK 30 3 Q9UKL0 Q9UKL0 RCOR1 REST corepressor 1 1 0 EREES(1)EDELEEANGNNPIDIEVDQNKESKK 77.894 7.73E-06 53533000 3763.3 2139.8 2414.4 2366.3 2075.7 3620 2106.6 2141.9 3613.1 2870.1 TRUE FALSE FALSE 3465.430834 2324.754777 2503.879788 2356.508878 2050.948633 2869.171194 2165.705526 2794.95545 3216.75197 2969.835761 1.166876256 0.782789004 0.843103791 0.793481211 0.690593285 0.966104332 0.729234106 0.941114484 1.083141368 1 11.53616743 -7.254269764 24.99294173 1.078802677 0.817760661 0.650377544 0.08813112 259.2089465 903590.4449 0.015616448 0.018909088 5.57E-08 7.254269764 -0.261042016 EREKEIS(ph)DDEAEEEK ddPTM_HeLa_Curcumin_4h_R1 1 EREKEISDDEAEEEK 15 2 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 1 0 EREKEIS(1)DDEAEEEK 50.024 0.018555 19399000 7337.2 6208.6 6984 7001.4 7581.9 7173.1 6369 7774.1 6322.4 6115.7 TRUE FALSE FALSE 6756.452878 6745.243719 7242.833184 6972.430062 7491.490794 5685.318203 6547.696999 10144.3873 5628.848538 6328.22012 1.067670332 1.065899035 1.144529275 1.101799547 1.183822726 0.89840715 1.034682245 1.603039577 0.889483683 1 12.62758407 -4.260581061 24.90783025 1.048332389 1.60303976 0.776094003 0.090213963 20.49098576 594528.4831 0.010614914 0.085985335 5.49E-05 4.260581061 0.554707371 ERELEEAR ddPTM_HeLa_Curcumin_4h_R1 3 ERELEEAR 8 1 Q9Y490;Q9Y4G6;H0YMT1;A0A1B0GVU7 Q9Y490;Q9Y4G6 TLN1;TLN2 Talin-1;Talin-2 0 0 ;; ;; 153.04 0.0013985 24515700 6000.65 5297.41 5415.35 5444.38 5123.29 6848.7 5020.45 5267.4 6762.3 5629.32 FALSE FALSE TRUE 5525.692221 5755.294516 5616.047635 5421.852598 5062.198113 5428.202419 5161.310315 6873.406012 6020.492608 5824.938451 0.948626714 0.988043833 0.964138537 0.930799981 0.869056069 0.93189009 0.886071219 1.179996333 1.033571884 1 12.50802709 -9.364514877 0.700835946 1.005793094 0.954410587 0.05179447 0.08145632 2.947669128 2.109260493 0.093539388 0.015844049 4.32E-10 9.364514877 -0.051382508 ERENMDTDDERQYQDFLEDLEEDEAIRK ddPTM_HeLa_Curcumin_4h_R1 2 ERENMDTDDERQYQDFLEDLEEDEAIRK 28 3 C9JA08;Q96D46 C9JA08 NMD3 60S ribosomal export protein NMD3 0 0 ; ; 60.517 0.00063 9762100 2028.35 1885.86 1804.53 1972.27 1745.82 2270.62 1832.74 1693.01 2092.17 1945.95 FALSE FALSE TRUE 1867.803957 2048.865335 1871.407469 1964.109269 1725.002237 1799.667817 1884.161752 2209.200955 1862.664185 2013.571618 0.927607412 1.017527918 0.929397024 0.975435516 0.856687799 0.893768963 0.935731183 1.097155391 0.925054847 1 10.97554107 EREQQIEEHRR ddPTM_HeLa_Curcumin_4h_R1 1 EREQQIEEHRR 11 2 Q16643-3;Q16643;Q16643-2;D6R9W4 Q16643-3 DBN1 Drebrin 0 0 81.017 0.01036 3136300 482.19 385.85 559.96 420.59 568.42 634.29 419.33 313.88 656.08 473.73 FALSE FALSE TRUE 444.0241527 419.2011547 580.7126102 418.84971 561.6419627 502.7311041 431.0952712 409.5805671 584.1096654 490.1920822 0.905816656 0.855177327 1.184663382 0.854460374 1.145758944 1.025579813 0.879441523 0.835551168 1.191593432 1 8.937203371 -4.605873151 5.563864146 0.973800715 0.845790554 0.140696448 0.125682692 0.238917807 11.82466934 0.014058451 0.055487277 2.48E-05 4.605873151 -0.128010161 ERESSANNSVS(ph)PSESLR ddPTM_HeLa_Curcumin_4h_R1 4 ERESSANNSVSPSESLR 17 1 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 0 ERESSANNS(0.012)VS(0.987)PSESLR;ERESSANNS(0.001)VS(0.781)PS(0.2)ES(0.018)LR;ERESSANNS(0.002)VS(0.993)PS(0.005)ESLR;ERESSANNS(0.001)VS(0.999)PSESLR ;;; 136.67 0.00015396 210775000 7652.9 6201.11 6360.6 6926.4 6263.9 6600.2 5076.69 4668.33 7463.1 6659.8 TRUE FALSE FALSE 7047.16489 6737.106317 6596.329431 6897.740392 6189.207084 5231.24412 5219.128258 6091.682327 6644.416602 6891.227554 1.022628383 0.977635155 0.957206736 1.000945091 0.898128386 0.759116439 0.757358282 0.883976371 0.964184762 1 12.75054528 -5.556262798 2.889114964 1.00340116 0.796608027 0.811995921 0.039789271 0.067587195 1.143993062 0.005555664 0.012581125 2.78E-06 5.556262798 -0.206793132 EREVDEDS(ph)EPER ddPTM_HeLa_Curcumin_4h_R1 1 EREVDEDSEPER 12 1 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 0 EREVDEDS(1)EPER 78.508 0.011408 11908000 3853.2 3492.7 4032.3 3944.6 4299.7 4445.4 3671.4 3235.6 4151.2 3568.9 TRUE FALSE FALSE 3548.215154 3794.593425 4181.740585 3928.27829 4248.428886 3523.37393 3774.409603 4222.119545 3695.823746 3692.919009 0.96081586 1.027532262 1.132367261 1.063732587 1.150425686 0.954089142 1.022066716 1.143301419 1.000786569 1 11.85054591 -7.000023337 24.99997728 0.982163622 1.072840093 0.337489356 0.056930796 0.681313474 730468.7238 0.009095576 0.011887125 1.00E-07 7.000023337 0.09067647 ERGVGQADWT(ph)PDLGLR ddPTM_HeLa_Curcumin_4h_R1 1 ERGVGQADWTPDLGLR 16 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 ERGVGQADWT(1)PDLGLR 75.319 0.014658 5570700 1796.1 1334.4 1806.8 1704.9 1565.5 2515.8 1817 1272.1 1846.6 1444.9 TRUE FALSE FALSE 1653.93679 1449.73959 1873.761597 1697.845576 1546.832435 1993.994721 1867.98013 1659.957434 1644.0326 1495.110167 1.106230715 0.969654024 1.253259886 1.135598976 1.034594285 1.333677454 1.249392968 1.110257605 1.099606327 1 10.54603608 -6.732804083 0.245247767 0.982642966 1.26321135 0.226568307 0.098147984 2.146101547 0.383332992 0.128031558 0.224212381 1.85E-07 6.732804083 0.280568384 ERLDDWDR ddPTM_HeLa_Curcumin_4h_R1 1 ERLDDWDR 8 1 H0YIQ2;P49750-3;P49750-1;P49750 H0YIQ2 YLPM1 YLP motif-containing protein 1 0 0 101.25 0.012348 4773500 1605.1 1416.9 1515.9 1708.4 1719.8 1660.6 1419.8 839.33 1637 1206.6 FALSE FALSE TRUE 1478.054641 1539.370522 1572.080588 1701.331093 1699.292508 1316.172841 1459.635767 1095.237853 1457.425196 1248.52926 1.183836606 1.232947093 1.259145971 1.362668179 1.36103539 1.054178611 1.169084148 0.877222415 1.167313608 1 10.28601392 -8.8930155 0.853814022 1.006035823 1.196618371 0.028411582 0.144076874 0.695705846 0.970935784 0.076823376 0.028160079 1.28E-09 8.8930155 0.190582548 ERLELCDER ddPTM_HeLa_Curcumin_4h_R1 2 ERLELCDER 9 1 P07919 P07919 UQCRH "Cytochrome b-c1 complex subunit 6, mitochondrial" 0 0 ; ; 139.15 0.0021391 10548000 10793 7758.1 9662.3 10332.4 10216.8 14320.5 8903.9 8683.4 11481.9 8747.6 FALSE FALSE TRUE 9938.722661 8428.675595 10020.39334 10289.64727 10094.97133 11350.26687 9153.71947 11330.92869 10222.3643 9051.578449 1.09800989 0.931182958 1.107032701 1.136779328 1.115271926 1.253954428 1.011284333 1.251817984 1.129346042 1 13.14395368 -6.532611463 24.85605609 1.037998627 1.146582346 0.300690607 0.081721773 169.8746632 433835.8165 0.011647928 0.016484696 2.93E-07 6.532611463 0.108583719 ERLGS(ph)FGSITR ddPTM_HeLa_Curcumin_4h_R1 3 ERLGSFGSITR 11 1 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 0 ERLGS(0.946)FGS(0.054)ITR;ERLGS(0.997)FGS(0.003)ITR;ERLGS(0.997)FGS(0.003)ITR ;; 80.746 0.011876 94966000 4705.4 3825 4280.7 3947.3 3850 5893.3 5242 1867.38 5309.8 4107.7 TRUE FALSE FALSE 4332.962625 4155.615956 4439.346508 3930.967118 3804.091265 4670.963149 5389.076412 2436.735566 4727.328224 4250.442269 1.019414534 0.977690248 1.044443431 0.924837198 0.894987162 1.098935794 1.267886039 0.573289886 1.112196784 1 12.05339725 -6.277739738 23.35773762 1.008944376 0.974534275 0.035896216 0.168645573 1959.339689 2807651.013 0.023517116 0.036003309 5.28E-07 6.277739738 -0.034410101 LQELNAHIVVS(ph)DPEDITDCPR ddPTM_HeLa_Curcumin_4h_R1 1 LQELNAHIVVSDPEDITDCPR 21 0 Q16513-3;Q16513-2;Q16513;B1AL79 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 0 LQELNAHIVVS(0.996)DPEDIT(0.004)DCPR 105.52 3.09E-05 25742000 3079.8 2362.2 2982.6 3257 2937.2 3129.1 1462 625.81 3389.7 2977.3 TRUE FALSE FALSE 2836.03058 2566.378042 3093.13778 3243.523397 2902.175808 2480.089388 1503.019785 816.6165881 3017.858391 3080.760953 0.920561713 0.833033812 1.004017458 1.052831896 0.942032132 0.805024935 0.487872902 0.265069767 0.979582135 1 11.58907103 -4.68190363 1.722026376 0.961434244 0.237007084 0.946955752 0.055885229 0.078714322 0.38303127 0.009022084 0.071739352 2.08E-05 4.68190363 -0.724427159 down ERPLQQVS(ph)PVASVPWR ddPTM_HeLa_Curcumin_4h_R1 2 ERPLQQVSPVASVPWR 16 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 ERPLQQVS(0.859)PVAS(0.141)VPWR;ERPLQQVS(1)PVASVPWR ; 146.86 0.0025337 9064100 2533.93 1869.38 1957.62 2180.2 2211.15 2902.96 2595.02 3139.4 2764.99 2196.19 TRUE FALSE FALSE 2333.366767 2030.960877 2030.171119 2171.17891 2184.78348 2300.853373 2667.829277 4096.588608 2461.677515 2272.507439 1.026780695 0.893709232 0.893361705 0.955411134 0.961397724 1.012473417 1.173958435 1.802673354 1.083242885 1 11.1500693 -4.215269903 2.071967686 0.987331344 2.096665249 0.952193619 0.055486903 0.12237886 0.514883378 0.008015675 0.264232492 6.09E-05 4.215269903 1.109333905 ERPSGPES(ph)PVQGPR ddPTM_HeLa_Curcumin_4h_R1 2 ERPSGPESPVQGPR 14 1 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 1 0 ERPS(0.006)GPES(0.994)PVQGPR;ERPS(0.005)GPES(0.995)PVQGPR ; 106.87 0.0015073 55679000 4545.5 4585.1 4177.2 4376.5 3743.9 4188.9 3601.4 2669.6 4325.7 4959.7 TRUE FALSE FALSE 4185.718879 4981.415613 4332.010707 4358.391203 3699.256438 3320.074921 3702.445591 3483.548751 3851.181532 5132.049206 0.815603809 0.970648451 0.844109348 0.849249691 0.720814686 0.646929674 0.721436105 0.678783194 0.750417889 1 12.32531929 -2.308363191 0.104415671 1.110394557 5.18E-12 0.333986036 0.091882554 34.10471675 0.338683538 0.535096958 5.421270128 0.004916282 2.308363191 -1.110394557 ERPSS(ph)AIYPSDSFR ddPTM_HeLa_Curcumin_4h_R1 1 ERPSSAIYPSDSFR 14 1 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 0 ERPS(0.096)S(0.904)AIYPSDSFR 184 0.00070247 23500000 1847.2 1495.5 1833.4 1845.4 2048.3 3476.9 2625.9 970.38 2238.4 1612 TRUE FALSE FALSE 1700.992171 1624.764356 1901.347417 1837.764224 2023.87536 2755.751747 2699.575687 1266.244395 1992.85312 1668.01688 1.019769159 0.974069493 1.139884997 1.101765963 1.213342254 1.652112626 1.618434273 0.759131643 1.194743977 1 10.70391817 -5.716285898 2.559539512 1.019115187 1.37504989 0.183246304 0.239138799 0.239543518 3.196554405 0.032672522 0.069900569 1.92E-06 5.716285898 0.355934703 ERQAQAQES(ph)EEEEESR ddPTM_HeLa_Curcumin_4h_R1 1 ERQAQAQESEEEEESR 16 1 H0YLQ7;Q9NVM6 H0YLQ7 DNAJC17 DnaJ homolog subfamily C member 17 1 0 ERQAQAQES(0.986)EEEEES(0.014)R 78.554 0.0059509 12281000 1178.4 961.21 768.57 1348.4 1102.8 1267.2 1062.5 806.11 1422.2 1293.5 TRUE FALSE FALSE 1085.128397 1044.292709 797.0538803 1342.820678 1089.64983 1004.368436 1092.31089 1051.889228 1266.188218 1338.449029 0.81073569 0.780225983 0.595505591 1.003266205 0.814113804 0.750397224 0.816101971 0.785901596 0.946011533 1 10.38634648 -8.924854767 0.748755866 1.001539674 0.793984354 0.357938862 0.094450767 0.524687946 0.541607202 0.061492732 0.019406609 1.19E-09 8.924854767 -0.207555321 ERQDNPK(ac)LDSMR ddPTM_HeLa_Curcumin_4h_R1 3 ERQDNPKLDSMR 12 2 Q6IN85-4;Q6IN85-2;Q6IN85;G3V5Z3 Q6IN85-4 SMEK1 Serine/threonine-protein phosphatase 4 regulatory subunit 3A 0 1 ;; ERQDNPK(1)LDSMR;ERQDNPK(1)LDSMR;ERQDNPK(1)LDSMR 108.32 0.00088697 11274500 3246.72 3727.69 3629.3 3764.95 3261.36 3429.21 2884.03 4440.16 3188.41 4010.32 FALSE TRUE FALSE 2989.738686 4049.894913 3763.805051 3749.371634 3222.470412 2717.953191 2964.94812 5793.944344 2838.6494 4149.678321 0.720474807 0.975953941 0.907011281 0.90353308 0.776559088 0.654979249 0.714500713 1.396239394 0.684064927 1 12.01878379 -9.698924008 1.590639893 0.999843466 0.844643174 0 0.222954074 0.860138238 3.930617982 0.138115111 0.030640279 2.00E-10 9.698924008 -0.155200292 ERQEAEEAKEALLQASR ddPTM_HeLa_Curcumin_4h_R1 2 ERQEAEEAKEALLQASR 17 2 P26038 P26038 MSN Moesin 0 0 ; ; 89.466 0.0017519 27965000 4145.9 3160.7 3400.5 3853.3 3350.6 5193.9 3516.5 3748.3 5740.1 3977.7 FALSE FALSE TRUE 3817.74764 3433.896824 3526.525521 3837.356066 3310.646283 4116.626593 3615.163526 4891.139415 5110.425391 4115.924779 0.927555251 0.834295331 0.856800284 0.93231929 0.804350531 1.000170512 0.878335665 1.18834519 1.24162264 1 12.0070009 -4.253649475 24.82946742 0.934045755 1.188345326 0.280280228 0.117988378 555.2032474 1769602.735 0.010262993 0.147557573 5.58E-05 4.253649475 0.254299571 ERQTNPSAMEVEEDDPVPEIR ddPTM_HeLa_Curcumin_4h_R1 1 ERQTNPSAMEVEEDDPVPEIR 21 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 128.05 9.96E-05 3905100 718.79 623.1 937.79 683.14 840.45 825.81 771.36 698.23 913.35 835.94 FALSE FALSE TRUE 661.897013 676.9579875 972.5453224 680.3133477 830.4281827 654.5276972 793.0022856 911.1171127 813.1577901 864.9888528 0.76520872 0.782620476 1.124344342 0.786499555 0.960044953 0.75668917 0.916777463 1.053328155 0.940078924 1 9.75653773 -4.295583697 4.340197951 0.885406318 1.061033731 0.153002488 0.114197236 0.282493261 11.54653577 0.016825646 0.139430401 5.06E-05 4.295583697 0.175627413 AKSPTPES(ph)STIASYVTLR ddPTM_HeLa_Curcumin_4h_R1 1 AKSPTPESSTIASYVTLR 18 1 A0JP02;B4DJX4;Q9HAU0-8;Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;Q9HAU0-5;H0YGJ6 A0JP02 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 0 AKS(0.007)PT(0.051)PES(0.736)S(0.193)T(0.012)IASYVTLR 164.93 0.00017248 130880000 1381 1391.2 1285 1079.6 1265.4 1556.6 673.9 380.36 1506.4 1084.5 TRUE FALSE FALSE 1271.692393 1511.449129 1332.62323 1075.132901 1250.310931 1233.743614 692.8078203 496.330013 1341.151689 1122.186294 1.133227521 1.346878978 1.187524065 0.958069892 1.114174124 1.099410695 0.617373268 0.442288429 1.195123925 1 10.13209648 -4.680692723 3.58931764 1.092542836 0.476307699 0.831452986 0.108040383 0.072323708 1.772551593 0.016356003 0.071384123 2.09E-05 4.680692723 -0.616235137 down ERS(ph)PALKS(ph)PLQSVVVR ddPTM_HeLa_Curcumin_4h_R1 1 ERSPALKSPLQSVVVR 16 2 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 2 0 ERS(1)PALKS(0.983)PLQS(0.017)VVVR 95.409 0.01037 25089000 1786.3 1309.9 1464.7 1821.5 1679.5 2107.7 1744.4 1588.2 2016.9 1698.2 TRUE FALSE FALSE 1644.91247 1423.121919 1518.98307 1813.963116 1659.473059 1670.539261 1793.343169 2072.434869 1795.651116 1757.212324 0.936092041 0.809874766 0.864427736 1.032295922 0.944378227 0.950675817 1.020561457 1.179387853 1.021874871 1 10.77907281 -4.269461703 2.009402987 0.951602006 1.244490615 0.547129367 0.06471657 0.458591809 1.985226745 0.00960738 0.244299915 5.38E-05 4.269461703 0.292888609 ERS(ph)PS(ph)PLRGNVVPS(ph)PLPTR ddPTM_HeLa_Curcumin_4h_R1 2 ERSPSPLRGNVVPSPLPTR 19 2 H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9;Q9Y2V2 H3BTK3 CARHSP1 Calcium-regulated heat stable protein 1 3 0 ERS(1)PS(1)PLRGNVVPS(0.999)PLPT(0.002)R;ERS(1)PS(1)PLRGNVVPS(0.975)PLPT(0.025)R ; 72.167 0.0065742 18097800 4320.1 3685.1 4950.4 3939.9 4577.1 4883.4 3567.6 3017.9 4428.9 4142.7 TRUE FALSE FALSE 3978.159526 4003.623624 5133.866179 3923.597738 4522.521072 3870.527793 3667.697254 3938.043817 3943.060751 4286.658517 0.928032758 0.933973072 1.197638244 0.915304478 1.055022474 0.902924219 0.855607518 0.918674488 0.919844848 1 12.06563778 -5.071494497 9.125029678 0.981830679 0.885166646 0.232317068 0.082286261 0.458891017 56.00503943 0.011114244 0.028462588 8.48E-06 5.071494497 -0.096664033 ERS(ph)PSPSFR ddPTM_HeLa_Curcumin_4h_R1 1 ERSPSPSFR 9 1 C9JEJ2;P49585 C9JEJ2 PCYT1A Choline-phosphate cytidylyltransferase A 1 0 ERS(0.977)PS(0.02)PS(0.003)FR 69.346 0.020254 20228000 364.85 419.66 573.13 324.28 463.94 519.67 392.02 552.11 457.63 262.33 TRUE FALSE FALSE 335.9717375 455.9335404 594.370702 322.9382153 458.4078185 411.8845841 403.0190261 720.4457974 407.4291339 271.445948 1.237711375 1.67964762 2.189646618 1.189696209 1.688762798 1.51737238 1.484711889 2.654104078 1.500958614 1 8.084521138 -1 0.100926338 0.555131746 4.944658281 0.244508873 0.404013225 81.34727716 0.584528802 2.929225425 49.69606401 0.1 1 4.389526534 ERS(ph)RT(ph)GSESS(ph)QTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 1 ERSRTGSESSQTGTSTTSSR 20 2 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 3 0 ERS(0.997)RT(0.995)GS(0.06)ES(0.091)S(0.671)QT(0.017)GT(0.029)S(0.011)T(0.021)T(0.008)S(0.048)S(0.052)R 72.122 0.012646 8218600 4288.1 3929.2 4076.6 4169.5 2705.6 3910.7 3565.7 2357.3 4566.1 6403.2 TRUE FALSE FALSE 3948.69236 4268.82254 4227.682382 4152.247714 2673.337487 3099.576737 3665.743945 3076.029918 4065.210254 6625.710723 0.595965101 0.644281454 0.638072285 0.626687142 0.403479355 0.467810453 0.553260488 0.464256598 0.613550821 1 12.6938595 -13.52287875 0.161493753 2.830993722 0.409101195 0.21476184 0.137571773 13.40344193 0.143976003 7.694299139 0.118786959 3.00E-14 13.52287875 -2.421892527 ERSDS(ph)GGSSSEPFDR ddPTM_HeLa_Curcumin_4h_R1 1 ERSDSGGSSSEPFDR 15 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 0 ERS(0.007)DS(0.993)GGS(0.001)SSEPFDR 152.59 0.00018172 58431000 938.43 683.62 705.99 826.94 782.33 1022.5 802.74 215.85 1225.8 837.97 TRUE FALSE FALSE 864.1522753 742.7090666 732.1546105 823.5183414 773.0012257 810.421974 825.2627239 281.6616713 1091.332807 867.0893951 0.996612668 0.856554204 0.844381923 0.949750217 0.891489655 0.934646391 0.951761985 0.324835793 1.258616254 1 9.76003693 -4.261209009 6.690860034 0.962079604 0.313435344 0.752239249 0.110200249 0.027759922 8.128542957 0.00975857 0.08094223 5.48E-05 4.261209009 -0.648644259 ERSDTFINLR ddPTM_HeLa_Curcumin_4h_R1 1 ERSDTFINLR 10 1 P17655;P17655-2 P17655 CAPN2 Calpain-2 catalytic subunit 0 0 96.113 0.01307 2789300 848.98 685.37 855.03 683.69 780.68 892.98 815.46 581.77 998.05 975.62 FALSE FALSE TRUE 781.7823372 744.6103289 886.718164 680.8610719 771.3709009 707.765882 838.3396129 759.1489949 888.566412 1009.522722 0.774407866 0.737586497 0.878353844 0.674438581 0.76409464 0.7010896 0.830431643 0.751988022 0.880184658 1 9.979457668 -9.174559981 0.544094377 1.039437123 0.756594086 0.50006502 0.066019627 0.494296305 0.215037439 0.07196145 0.013049614 6.69E-10 9.174559981 -0.282843037 DSAIPVES(ph)DTDDEGAPR ddPTM_HeLa_Curcumin_4h_R1 3 DSAIPVESDTDDEGAPR 17 0 C9JA08;Q96D46 C9JA08 NMD3 60S ribosomal export protein NMD3 1 0 DSAIPVES(0.868)DT(0.132)DDEGAPR;DSAIPVES(0.84)DT(0.16)DDEGAPR;DSAIPVES(0.5)DT(0.5)DDEGAPR ;; 244.54 1.24E-30 241690000 14230.03 11407.11 12752.86 13503.7 12965.66 15493.28 15315.1 21939.7 15259 13194.5 TRUE FALSE FALSE 13103.70811 12393.08976 13225.49221 13447.82527 12811.05297 12279.79908 15744.80049 28629.01353 13585.12588 13653.00789 0.959767123 0.90771864 0.96868707 0.984971617 0.93833191 0.899420785 1.153211117 2.096901559 0.995028054 1 13.73693121 -4.264767173 3.056204588 0.967833292 2.271361344 0.989423619 0.035180569 0.026440617 0.367236291 0.005267893 0.082800233 5.44E-05 4.264767173 1.303528052 up ERTDVIQGDDVADATSEVEVS(ph)STSETTPK ddPTM_HeLa_Curcumin_4h_R1 1 ERTDVIQGDDVADATSEVEVSSTSETTPK 29 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 ERTDVIQGDDVADATSEVEVS(0.194)S(0.194)T(0.152)S(0.152)ET(0.156)T(0.152)PK 72.035 0.00038136 0 507.66 440.98 533.47 547.98 521.12 779.29 610.63 934.78 671.46 535.15 TRUE FALSE FALSE 467.4781753 479.0963462 553.2408675 545.712604 514.9059844 617.6564696 627.7626344 1219.790119 597.8025179 553.7464227 0.844209834 0.865190865 0.999087028 0.985491882 0.9298588 1.115413923 1.133664451 2.202795483 1.079560054 1 9.113081663 ERTDVIQGDDVADATSEVEVSST(ph)SETTPK ddPTM_HeLa_Curcumin_4h_R1 1 ERTDVIQGDDVADATSEVEVSSTSETTPK 29 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 ERTDVIQGDDVADAT(0.001)S(0.002)EVEVS(0.076)S(0.076)T(0.212)S(0.212)ET(0.212)T(0.212)PK 61.522 0.0038811 0 638.11 599.51 572.11 691.16 722.84 641.59 697.1 993.03 679.58 671.44 TRUE FALSE FALSE 587.6029202 651.328973 593.3128999 688.3001631 714.2206051 508.5170018 716.6587499 1295.800276 605.0317742 694.77249 0.845748686 0.937470873 0.853967174 0.99068425 1.027992063 0.731918735 1.031501333 1.865071364 0.870834385 1 9.44039682 -4.270585666 4.035805451 0.921303552 1.94021217 0.918465553 0.084964238 0.043880751 1.504658151 0.012034234 0.128226771 5.36E-05 4.270585666 1.018908618 VTFS(ph)VSPIEATEK ddPTM_HeLa_Curcumin_4h_R1 1 VTFSVSPIEATEK 13 0 Q9ULD2-2;Q9ULD2;H0YC63;Q9ULD2-5 Q9ULD2-2 MTUS1 Microtubule-associated tumor suppressor 1 1 0 VT(0.086)FS(0.906)VS(0.009)PIEATEK 167.73 0.00018658 6739400 2549.7 2358.2 2488.9 2399 2423.9 2865.4 1431.6 830.66 2912.8 2500 TRUE FALSE FALSE 2347.888555 2562.0323 2581.140823 2389.073574 2394.996576 2271.08374 1471.766843 1083.92441 2593.273127 2586.874814 0.907615839 0.990396708 0.997783429 0.923536601 0.925826237 0.877925645 0.568936245 0.419009225 1.002473376 1 11.33699452 -4.680672315 1.910989813 0.957906642 0.399573754 0.968325312 0.034049217 0.056268103 0.354176543 0.005810955 0.041420753 2.09E-05 4.680672315 -0.558332887 down ES(ph)HTPVSIQEEIVGDFK ddPTM_HeLa_Curcumin_4h_R1 1 ESHTPVSIQEEIVGDFK 17 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;A0A0A0MR81;F5H176 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 0 ES(0.58)HT(0.419)PVS(0.001)IQEEIVGDFK 102.72 0.00078849 2124500 2267.2 2233.9 2456.7 2652.9 2954.7 2910.9 2277.9 1587.6 2575.6 2400.3 TRUE FALSE FALSE 2087.748728 2426.988362 2547.747463 2641.923003 2919.467132 2307.146527 2341.811743 2071.651932 2293.063124 2483.710246 0.840576605 0.977162439 1.025782885 1.063700167 1.175445943 0.928911305 0.942868335 0.834095658 0.923240997 1 11.27828116 -10.04799503 2.673902921 1.001085948 0.947835859 0 0.101310419 1.106026338 14.39660657 0.096863366 0.016677605 8.95E-11 10.04799503 -0.053250089 ES(ph)LCDSPHQNLSR ddPTM_HeLa_Curcumin_4h_R1 1 ESLCDSPHQNLSR 13 0 O15042-2;O15042;E7ET15;U3KPT1;C9JDJ7;C9J5L1;E7EW00;H0Y8D9 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 1 0 ES(0.538)LCDS(0.462)PHQNLSR 177.21 0.00020053 7856400 1305.1 991.16 1081.3 1182.9 1338.5 1408.9 1269.1 654.09 1384.7 909.61 TRUE FALSE FALSE 1201.799958 1076.831454 1121.373929 1178.005473 1322.539262 1116.678258 1304.70753 853.5190299 1232.801874 941.2188798 1.27685492 1.144081868 1.191406115 1.25157442 1.40513465 1.18641719 1.38618929 0.906823108 1.309792973 1 9.878386449 -9.373449455 0.839769061 0.982941882 1.231495633 0 0.162799652 0.694899074 0.776737752 0.11786164 0.023296954 4.23E-10 9.373449455 0.248553751 ES(ph)PEGSYTDDANQEVR ddPTM_HeLa_Curcumin_4h_R1 2 ESPEGSYTDDANQEVR 16 0 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 0 ES(1)PEGSYTDDANQEVR;ES(0.998)PEGS(0.002)YTDDANQEVR ; 252.37 4.58E-40 29669000 2667.67 2757.67 2609.63 2541.29 2415.97 2667.23 2021.47 1722.33 2522.27 2195.9 TRUE FALSE FALSE 2456.521105 2996.030707 2706.345183 2530.774815 2387.161136 2114.016432 2078.187008 2247.460488 2245.583291 2272.207362 1.081116603 1.318555145 1.19106435 1.113795712 1.050591234 0.930380065 0.914611511 0.989108884 0.988282729 1 11.14987879 -5.347420396 4.201477573 1.079981888 0.94153399 0.363632277 0.094089308 0.248421825 7.974704108 0.015629254 0.036735083 4.49E-06 5.347420396 -0.138447898 ES(ph)PS(ph)S(ph)KT(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 ESPSSKTGK 9 1 A0A1B0GU80;Q96N23-2;Q96N23 A0A1B0GU80 CFAP54 Cilia- and flagella-associated protein 54 4 0 ES(1)PS(1)S(1)KT(1)GK 72.006 0.0071552 0 3334.7 4590.8 3984.1 3275.2 2559.3 4110.5 4008.5 3167.4 3739.4 5590.6 TRUE FALSE FALSE 3070.754976 4987.608296 4131.754251 3261.64809 2528.782019 3257.935965 4120.967722 4133.125679 3329.197176 5784.872934 0.530824966 0.862181132 0.714234227 0.563823636 0.437137003 0.563181941 0.712369618 0.714471299 0.575500484 1 12.49806956 -9.431343614 0.896850443 1.026295994 0.628041293 0 0.173773292 0.416961196 0.532566814 0.11939097 0.023050216 3.70E-10 9.431343614 -0.398254701 ES(ph)RSPQQSAALPR ddPTM_HeLa_Curcumin_4h_R1 1 ESRSPQQSAALPR 13 1 A0A0A6YYG7;Q6IBW4-2;Q6IBW4;Q6IBW4-4;E5RJN3 A0A0A6YYG7 NCAPH2 Condensin-2 complex subunit H2 1 0 ES(0.864)RS(0.136)PQQSAALPR 123.95 0.00093664 120380000 636.7 471.92 644.77 668.04 755.66 791.58 528.11 510.74 743.94 551.81 TRUE FALSE FALSE 586.3045232 512.710662 668.6657434 665.2758275 746.649248 627.3973851 542.9273453 666.4622748 662.3316432 570.9853564 1.026829351 0.897940124 1.171073366 1.165136408 1.307650432 1.09879768 0.950860366 1.167214303 1.159980087 1 9.157309936 -6.739460431 24.99701208 1.004418704 1.141120141 0.250410406 0.10194902 205.5891445 233819.3729 0.01448446 0.020474562 1.82E-07 6.739460431 0.136701437 ES(ph)SPIPS(ph)PTSDRK ddPTM_HeLa_Curcumin_4h_R1 1 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 2 0 ES(0.5)S(0.5)PIPS(0.975)PT(0.021)S(0.004)DRK 97.073 0.0034968 93758000 6447.3 5553.5 6098.3 5749.7 6408.2 6534 4934.6 4919.4 6106.2 5396.9 TRUE FALSE FALSE 5936.989402 6033.519794 6324.308363 5725.909265 6331.7864 5178.774747 5073.051595 6419.302414 5436.365137 5584.441873 1.063130307 1.0804159 1.132487096 1.025332414 1.133826181 0.927357624 0.908425893 1.149497579 0.973484058 1 12.44719739 -3.946378617 19.4867043 1.034148736 2.428951459 0.192321746 0.073973813 74.86585937 88646.83748 0.009815706 9705.477912 0.000113141 3.946378617 1.394802723 QVVSVVQDEEVGLPFEASPESPPPAS(ph)PDGVTEIR ddPTM_HeLa_Curcumin_4h_R1 1 QVVSVVQDEEVGLPFEASPESPPPASPDGVTEIR 34 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 0 QVVSVVQDEEVGLPFEAS(0.013)PES(0.086)PPPAS(0.843)PDGVT(0.058)EIR 66.548 9.47E-06 1968200 1480 1206.1 1450 1288.3 1260.2 1772.5 2302.6 3794.2 1555.5 1477 TRUE FALSE FALSE 1362.856438 1310.34991 1503.738276 1282.969356 1245.172938 1404.86352 2367.204759 4951.034114 1384.865542 1528.32564 0.891731711 0.857376122 0.983912221 0.839460729 0.814730124 0.919217399 1.548887683 3.239515182 0.906132506 1 10.57773626 -4.26462547 2.159943017 0.923574255 3.856604422 0.991706771 0.064549072 0.047529857 0.247106193 0.011091345 0.267473845 5.44E-05 4.26462547 2.933030166 up ES(ph)SPLYS(ph)PTFSDSTSAVK ddPTM_HeLa_Curcumin_4h_R1 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 ES(0.74)S(0.26)PLY(0.002)S(0.753)PT(0.15)FS(0.023)DS(0.057)T(0.013)S(0.003)AVK 129.32 0.00016435 0 2727 3179 2222.5 2966.9 2646.1 2736.9 1820.7 3084.9 2655.1 2210.2 TRUE FALSE FALSE 2511.155072 3453.778595 2304.867805 2954.623754 2614.546986 2169.236089 1871.783942 4025.471809 2363.842173 2287.004285 1.098010655 1.51017583 1.007810882 1.291918766 1.143219102 0.948505476 0.818443566 1.760150532 1.033597614 1 11.15924335 -7.638222744 3.84544755 1.038537414 1.18561835 0.075377441 0.259882137 0.447670158 13.84843899 0.044979244 0.046997505 2.30E-08 7.638222744 0.147080936 ES(ph)SPLYS(ph)PTFSDSTSAVKEK ddPTM_HeLa_Curcumin_4h_R1 1 ESSPLYSPTFSDSTSAVKEK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 ES(0.51)S(0.451)PLY(0.19)S(0.776)PT(0.072)FS(0.001)DSTSAVKEK 82.482 0.0012317 0 1937.1 1063.7 1245.6 1428.9 981.91 1945.8 1303.8 1360.6 2672.9 1849.9 TRUE FALSE FALSE 1783.776491 1155.641488 1291.763032 1422.98759 970.2013646 1542.219146 1340.381119 1775.440677 2379.689557 1914.183887 0.931873109 0.603725429 0.674837481 0.74339127 0.506848569 0.805679724 0.70023634 0.927518348 1.24318754 1 10.90251371 -7.375873325 5.342372171 0.970263659 0.705003668 0.555206592 0.136923213 0.116221532 4.688489176 0.017772508 0.020217085 4.21E-08 7.375873325 -0.265259991 ES(ph)SPSHGLLK ddPTM_HeLa_Curcumin_4h_R1 1 ESSPSHGLLK 10 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 0 ES(0.497)S(0.497)PS(0.005)HGLLK 111.94 0.0032002 12346000 9847.2 8045.7 7183.8 7565.4 11553 13498 7279.1 3056.9 10427 8019.1 TRUE FALSE FALSE 9067.783729 8741.134457 7450.037948 7534.096379 11415.23802 10698.36265 7483.331955 3988.934738 9283.184187 8297.763128 1.092798576 1.053432633 0.897836903 0.907967155 1.375700637 1.289306827 0.90184931 0.480724103 1.118757434 1 13.01850676 -4.334251444 3.476995017 1.062785232 0.449748029 0.611812872 0.145745845 0.136467793 2.720000898 0.020843392 0.191962269 4.63E-05 4.334251444 -0.613037203 MPTQSEEEKLSPSPTT(ph)EDPR ddPTM_HeLa_Curcumin_4h_R1 1 MPTQSEEEKLSPSPTTEDPR 20 1 F6RRE2;E7EV10;Q9BTC8;E7EQY4;Q9BTC8-2 F6RRE2 MTA3 Metastasis-associated protein MTA3 1 0 MPTQSEEEKLS(0.019)PS(0.262)PT(0.262)T(0.457)EDPR 88.637 0.0011505 22392000 1535.3 1365.4 1389.9 1665.8 1245.9 2747.7 2709.6 3506.5 1402.6 1843.6 TRUE FALSE FALSE 1413.779385 1483.419092 1441.410917 1658.907361 1231.043456 2177.796047 2785.624083 4575.615708 1248.738289 1907.664963 0.741104655 0.777609864 0.755589134 0.869601001 0.645314287 1.141603001 1.460227104 2.398542615 0.654589938 1 10.8975921 -4.264217646 1.388066124 0.844674138 3.04543677 0.940522974 0.124507085 0.225435408 0.377962527 0.019497346 0.690866689 5.44E-05 4.264217646 2.200762631 up ESADPLGAWLQDAR ddPTM_HeLa_Curcumin_4h_R1 2 ESADPLGAWLQDAR 14 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 222.2 2.17E-13 14654200 3857.6 3048.7 3260.4 3383.2 3483.5 3937.5 3432.2 3484.6 3979.7 3622.6 FALSE FALSE TRUE 3552.266889 3312.216043 3381.233292 3369.201215 3441.961538 3120.818115 3528.498295 4547.038499 3543.136867 3748.48508 0.947654002 0.883614573 0.902026611 0.89881676 0.918227354 0.832554498 0.941313149 1.213033639 0.945218346 1 11.87209194 -4.261122658 24.4089949 0.943711175 1.213033746 0.754283819 0.048540648 9.020853351 694767.8524 0.008430481 0.065751205 5.48E-05 4.261122658 0.269322571 ESAPQVLLPEEEKIIVEET(ph)KSNGQTVIEEK ddPTM_HeLa_Curcumin_4h_R1 1 ESAPQVLLPEEEKIIVEETKSNGQTVIEEK 30 2 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5 B1ALK7 ARHGEF7 Rho guanine nucleotide exchange factor 7 1 0 ESAPQVLLPEEEKIIVEET(0.417)KS(0.417)NGQT(0.166)VIEEK 49.888 0.006225 2467700 1424.3 1359.5 1167.2 1181.6 1399 2573.4 1296.7 737.67 1647.4 1475 TRUE FALSE FALSE 1311.565152 1477.009122 1210.457459 1176.710852 1382.317839 2039.647832 1333.081912 962.5821872 1466.684342 1526.25614 0.85933489 0.967733451 0.793089329 0.77097862 0.90569191 1.336373219 0.873432628 0.630681942 0.960968676 1 10.57578138 -9.455038197 1.152168063 1.00079438 0.897833119 0.037845635 0.172916207 1.519276562 3.562409226 0.126317355 0.030328856 3.51E-10 9.455038197 -0.102961261 ESAS(ph)PTIPNLDLLEAHTK ddPTM_HeLa_Curcumin_4h_R1 2 ESASPTIPNLDLLEAHTK 18 0 O75151 O75151 PHF2 Lysine-specific demethylase PHF2 1 0 ES(0.046)AS(0.864)PT(0.09)IPNLDLLEAHTK;ES(0.164)AS(0.762)PT(0.074)IPNLDLLEAHTK ; 163.92 9.37E-06 42929300 9824.4 6846.9 8884.2 9294.2 8743.9 10133.4 8921.2 8111.9 10402.8 8663.1 TRUE FALSE FALSE 9046.788373 7438.715527 9213.456267 9255.743063 8639.634703 8031.618613 9171.504862 10585.18097 9261.638867 8964.14208 1.009219655 0.829830168 1.027812387 1.032529715 0.963799394 0.895971811 1.023132474 1.180835921 1.033187424 1 13.1299498 -4.295171046 3.928231174 0.98628286 1.193142132 0.480721349 0.063374201 0.143476466 4.310600644 0.008478663 0.079004964 5.07E-05 4.295171046 0.206859271 ESASSSSSVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 ESASSSSSVKK 11 1 Q9NPF5 Q9NPF5 DMAP1 DNA methyltransferase 1-associated protein 1 0 1 ; ESASSSSSVK(1)K;ESASSSSSVK(1)K 282.13 3.69E-97 23038000 4443.9 4028.1 4581 3538.4 3123.6 5594.9 3777.7 2948.9 3744.7 3895.8 FALSE TRUE FALSE 4092.160626 4376.271015 4750.77589 3523.759038 3086.35311 4434.454672 3883.692095 3848.006035 3333.915779 4031.17876 1.015127552 1.085605793 1.178507869 0.874126217 0.765620503 1.100039204 0.963413514 0.954561002 0.827032483 1 11.97698604 ESAWS(ph)PPPIEIR ddPTM_HeLa_Curcumin_4h_R1 2 ESAWSPPPIEIR 12 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 0 ES(0.03)AWS(0.97)PPPIEIR;ES(0.311)AWS(0.689)PPPIEIR ; 102.33 0.0079955 10932000 4425 3891.3 4434.1 4584.5 4706.8 6735.9 5062.2 2412.4 5229.2 3802 TRUE FALSE FALSE 4074.756581 4227.646633 4598.431647 4565.530554 4650.674484 5338.798411 5204.231708 3147.929655 4655.569843 3934.119217 1.035748119 1.074610707 1.168859252 1.160496239 1.182138676 1.35705049 1.32284545 0.800161226 1.183383011 1 11.94182496 -6.917192931 1.449591507 1.013952302 1.187156755 0.031660178 0.150649471 0.416430457 1.739416194 0.024519286 0.0336792 1.21E-07 6.917192931 0.173204453 ESCDSALR ddPTM_HeLa_Curcumin_4h_R1 1 ESCDSALR 8 0 P52907 P52907 CAPZA1 F-actin-capping protein subunit alpha-1 0 0 122.18 0.00249 2380900 2741.5 2452.4 2614.3 2509.1 2854.8 3262.3 2047 2537 2780.8 2564.8 FALSE FALSE TRUE 2524.507382 2664.374528 2711.188258 2498.718009 2820.758375 2585.662206 2104.433311 3310.519621 2475.753197 2653.926609 0.951234813 1.003936778 1.021576199 0.941517373 1.062862238 0.974277961 0.792950831 1.247404359 0.932864228 1 11.37391276 -7.20109747 24.88830361 0.976971852 0.997183149 0.024638849 0.107720644 1438.776298 593430.4685 0.016161808 0.019794084 6.29E-08 7.20109747 0.020211297 DGASS(ph)SPESASR ddPTM_HeLa_Curcumin_4h_R1 2 DGASSSPESASR 12 0 A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-2;Q14135;Q14135-4;G5E9M9;Q14135-5;Q14135-6 A0A075B6E4 VGLL4 Transcription cofactor vestigial-like protein 4 1 0 DGAS(0.144)S(0.428)S(0.428)PESASR;DGAS(0.003)S(0.499)S(0.499)PESASR ; 155.88 0.00032931 70854000 5894.1 5281.3 5687.1 5754 5434.6 5672.8 3355.5 1768.79 6058.1 5582.3 TRUE FALSE FALSE 5427.575766 5737.792039 5897.868929 5730.191473 5369.795944 4496.197334 3449.646299 2308.085928 5393.541587 5776.284509 0.939630961 0.993336119 1.021048897 0.992020297 0.929628022 0.778389175 0.597208516 0.399579682 0.933738907 1 12.49592609 -4.680342057 1.223058423 0.979037181 0.331112123 0.979907074 0.027815214 0.081987862 0.163450075 0.004763492 0.055299185 2.09E-05 4.680342057 -0.647925058 down FTPVASKFSPGAPGGS(ph)GSQPNQK ddPTM_HeLa_Curcumin_4h_R1 1 FTPVASKFSPGAPGGSGSQPNQK 23 1 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 0 FTPVAS(0.001)KFS(0.047)PGAPGGS(0.615)GS(0.337)QPNQK 126.04 2.44E-06 626090000 3930.7 2976.2 3338.1 3570.4 2888.1 3270.8 2057.2 1103.4 3777.3 3239.4 TRUE FALSE FALSE 3619.580947 3233.449466 3461.812922 3555.626631 2853.661294 2592.39921 2114.919495 1439.821581 3362.93964 3351.968909 1.079837268 0.964641843 1.032769998 1.060757641 0.851338831 0.773395959 0.630948423 0.429545029 1.003272922 1 11.71079305 -4.68011612 0.825510311 1.037122836 0.2871353 0.951296155 0.044673098 0.21746038 0.155511312 0.007781795 0.129660483 2.09E-05 4.68011612 -0.749987537 down AADRLPNLSS(ph)PSAEGPPGPPSGPAPR ddPTM_HeLa_Curcumin_4h_R1 1 AADRLPNLSSPSAEGPPGPPSGPAPR 26 1 O60784-3;O60784-4;O60784;O60784-2 O60784-3 TOM1 Target of Myb protein 1 1 0 AADRLPNLS(0.083)S(0.846)PS(0.071)AEGPPGPPSGPAPR 85.274 2.65E-05 96684000 902.22 554.44 857.36 779.49 721.2 810.98 893.98 1747.5 865.23 770.83 TRUE FALSE FALSE 830.808335 602.3633231 889.1345158 776.2646769 712.600161 642.7736064 919.0626728 2280.304705 770.3164337 797.6162851 1.041614057 0.755204394 1.114739672 0.973230727 0.893412251 0.805868208 1.15226167 2.858899383 0.965773202 1 9.639551056 -4.263906427 4.159185118 0.983691647 3.008033419 0.966084953 0.106761816 0.026646072 1.017048277 0.01462647 0.159883949 5.45E-05 4.263906427 2.024341772 up ESDQTLAALLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 9 ESDQTLAALLSPK 13 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 0 ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQTLAALLS(1)PK;ESDQT(0.001)LAALLS(0.999)PK ;;;;;;;; 192.4 6.51E-06 1037865400 25147.29 24346.33 25951.25 25022.36 27220.78 28358.22 26619.71 19173.32 24614.99 22086.65 TRUE FALSE FALSE 23156.85546 26450.71828 26913.02615 24918.8241 26896.18998 22476.40551 27366.58742 25019.177 21914.78718 22854.15944 1.01324468 1.15736999 1.1775986 1.090340871 1.176861921 0.983471108 1.197444495 1.094731883 0.958897099 1 14.48016914 -7.274945941 21.8672233 1.006254402 1.125352824 0.507757899 0.060191123 85.51943068 138456.1511 0.009131618 0.010486662 5.31E-08 7.274945941 0.119098422 ESDQTLAALLSPKES(ph)SGGEK ddPTM_HeLa_Curcumin_4h_R1 1 ESDQTLAALLSPKESSGGEK 20 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 0 ESDQTLAALLS(0.015)PKES(0.905)S(0.08)GGEK 64.5 0.0045945 4082800 1852.1 1561.6 1475.3 1773.5 1161.2 2245.6 1086.7 947.52 2803.3 2062.3 TRUE FALSE FALSE 1705.504331 1696.577746 1529.975916 1766.161727 1147.353448 1779.837247 1117.189877 1236.414486 2495.785004 2133.964771 0.799218597 0.795035498 0.716963999 0.827643338 0.537662788 0.834051841 0.523527798 0.579397796 1.169553048 1 11.05932064 -6.130927152 0.077183493 1.445884714 6.67E-16 0.705183064 0.105093877 13.81479491 0.404137365 2.96187125 4.544920789 7.40E-07 6.130927152 -1.445884714 ESDSAEGDEAES(ph)PEQQVR ddPTM_HeLa_Curcumin_4h_R1 1 ESDSAEGDEAESPEQQVR 18 0 Q8TEH3;Q8TEH3-7;Q8TEH3-6 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 0 ESDSAEGDEAES(1)PEQQVR 217.65 4.84E-17 3266800 735.73 617.57 701.2 787.38 605.43 893.66 641.45 602.11 561.9 677.18 TRUE FALSE FALSE 677.4961942 670.949999 727.1870888 784.1220302 598.2106427 708.3048424 659.4473606 785.6905672 500.2609758 700.7119546 0.966868325 0.95752612 1.037783192 1.119036182 0.853718334 1.010835962 0.941110475 1.121274672 0.713932412 1 9.4526777 ESDTKNEVNGTSEDIKSEGDTQS(ph)N ddPTM_HeLa_Curcumin_4h_R1 4 ESDTKNEVNGTSEDIKSEGDTQSN 24 2 O95232 O95232 LUC7L3 Luc7-like protein 3 1 0 ESDTKNEVNGTSEDIKS(0.013)EGDT(0.101)QS(0.886)N;ESDTKNEVNGTSEDIKSEGDT(0.014)QS(0.986)N;ESDTKNEVNGTSEDIKS(0.002)EGDT(0.022)QS(0.976)N;ESDTKNEVNGTSEDIKS(0.003)EGDT(0.044)QS(0.953)N ;;; 103.57 3.45E-06 397672000 8753.9 7355 8348.4 8212.8 8310.5 10226.2 8795.8 8635.1 8365.3 7311.8 TRUE FALSE FALSE 8061.019578 7990.733427 8657.799048 8178.81761 8211.402715 8105.170847 9042.586475 11267.90224 7447.647519 7565.884506 1.065443118 1.056153239 1.144320805 1.081012749 1.085319596 1.071278691 1.195179026 1.489304024 0.984372351 1 12.88529304 -1.000000029 0.823654959 1.044377169 133.9369313 0.902938544 0.042659949 120.8228786 0.357395898 0.007318861 30041.51871 0.099999993 1.000000029 132.8925541 ESDVPLKTEEFEVTK ddPTM_HeLa_Curcumin_4h_R1 1 ESDVPLKTEEFEVTK 15 1 M0QXF7;M0QYN0;Q969H8 M0QXF7 MYDGF Myeloid-derived growth factor 0 0 86.214 0.0054294 0 1197.1 985.77 1315.1 1213.3 1348.6 1290.9 1129 1171 1213.4 1048.7 FALSE FALSE TRUE 1102.348272 1070.975566 1363.838763 1208.279686 1332.518826 1023.152789 1160.676701 1528.032509 1080.293056 1085.142247 1.015856009 0.986944863 1.256829477 1.11347585 1.22796696 0.942874348 1.069607883 1.408140282 0.995531285 1 10.08366846 -6.783167016 24.99518651 1.006156048 1.155027713 0.336188773 0.115929217 222.6768829 256163.7432 0.017864202 0.023489603 1.65E-07 6.783167016 0.148871665 ESEAVEWQQK ddPTM_HeLa_Curcumin_4h_R1 4 ESEAVEWQQK 10 0 P26038 P26038 MSN Moesin 0 0 ;;; ;;; 193.82 2.78E-20 22991000 9600.6 7179.56 6958.74 7876.5 7724.3 10323.1 7159.65 8157.38 9423 7232.25 FALSE FALSE TRUE 8840.702379 7800.129175 7216.637026 7843.90913 7632.192767 8181.972695 7360.53051 10644.52761 8389.320475 7483.570149 1.181348234 1.042300536 0.964330778 1.048150679 1.019859855 1.093324781 0.983558698 1.422386294 1.121031848 1 12.86951098 -4.253267881 24.57080905 1.06478018 1.422386521 0.748337926 0.064226445 398.7129049 1198851.194 0.011066088 0.165008888 5.58E-05 4.253267881 0.357606341 ESEDDPES(ph)EPDDHEK ddPTM_HeLa_Curcumin_4h_R1 3 ESEDDPESEPDDHEK 15 0 P16383-3;P16383-4;P16383 P16383-3 GCFC2 GC-rich sequence DNA-binding factor 2 1 0 ESEDDPES(1)EPDDHEK;ESEDDPES(1)EPDDHEK;ESEDDPES(1)EPDDHEK ;; 157.83 0.00016231 91166900 17835.3 15578.6 15658.9 16718.4 16479.9 20738 18035.5 21598.9 18685.7 16244.1 TRUE FALSE FALSE 16423.61719 16925.14477 16239.23261 16649.22369 16283.38796 16436.70503 18541.52759 28184.30518 16635.92546 16808.58127 0.97709717 1.006934761 0.966127501 0.990519273 0.968754453 0.977875811 1.103098905 1.676780731 0.989728115 1 14.03691034 -4.250346653 2.759351644 0.986860652 1.817972028 0.9958194 0.01339034 0.021917441 0.219044943 0.002113207 0.041657083 5.62E-05 4.250346653 0.831111376 ESEDKPEIEDVGS(ph)DEEEEK ddPTM_HeLa_Curcumin_4h_R1 2 ESEDKPEIEDVGSDEEEEK 19 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 0 ESEDKPEIEDVGS(1)DEEEEK;ESEDKPEIEDVGS(1)DEEEEK ; 145.14 6.06E-05 376130000 17639.8 14689 19050.4 15148.3 21217.1 16452.2 17053.5 16068.6 12336.4 12467.2 TRUE FALSE FALSE 16243.59122 15958.65171 19756.42458 15085.62035 20964.09994 13039.82827 17531.97531 20967.84217 10983.12778 12900.43427 1.259150729 1.237063138 1.531454226 1.169388567 1.625069319 1.010805372 1.359022103 1.625359405 0.851376593 1 13.65513201 -9.975524986 0.205972332 0.646482335 1.447394351 0.458734639 0.188317001 8.799572293 0.415236469 1.864129116 0.239494207 1.06E-10 9.975524986 0.800912017 ESEDKPEIEDVGS(ph)DEEEEKK ddPTM_HeLa_Curcumin_4h_R1 2 ESEDKPEIEDVGSDEEEEKK 20 2 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 0 ESEDKPEIEDVGS(1)DEEEEKK;ESEDKPEIEDVGS(1)DEEEEKK ; 147.08 4.44E-05 110511000 4824.5 4277.6 5232.6 4039.4 6105.8 4528.5 4522.7 4258 3659.5 3718.1 TRUE FALSE FALSE 4442.635734 4647.336683 5426.524759 4022.686033 6032.992323 3589.238053 4649.59479 5556.244599 3258.062006 3847.303698 1.154740068 1.207946408 1.41047476 1.045585779 1.5681092 0.932922986 1.20853334 1.444191838 0.846842948 1 11.909632 -8.11463736 0.656249365 1.012354644 1.258482669 0.312498621 0.185080095 0.678428982 0.651547338 0.071015801 0.043841301 7.68E-09 8.11463736 0.246128024 ESEDKPEIEDVGS(ph)DEEEEKKDGDK ddPTM_HeLa_Curcumin_4h_R1 2 ESEDKPEIEDVGSDEEEEKKDGDK 24 3 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 1 0 ES(0.001)EDKPEIEDVGS(0.999)DEEEEKKDGDK;ESEDKPEIEDVGS(1)DEEEEKKDGDK ; 58.082 0.0035638 944153000 2658.5 2870.9 2937.7 2988.2 3648 2823.08 3016.16 3062.3 2790.75 2712.71 TRUE FALSE FALSE 2448.07692 3119.047804 3046.573746 2975.83562 3604.499983 2237.541385 3100.785332 3995.981173 2484.611707 2806.976471 0.872140164 1.111177039 1.085357778 1.060156952 1.284121909 0.797135782 1.104670938 1.423589123 0.885155873 1 11.45480126 -7.245430357 22.8959464 0.939621749 1.112695108 0.263127449 0.155035493 304.8884997 436047.9124 0.02517367 0.030759608 5.68E-08 7.245430357 0.173073358 ESEDS(ph)ETQPFDTHLEAYGPCLS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 2 ESEDSETQPFDTHLEAYGPCLSPPR 25 0 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 2 0 ES(0.158)EDS(0.756)ET(0.085)QPFDT(0.003)HLEAY(0.012)GPCLS(0.985)PPR;ES(0.04)EDS(0.826)ET(0.134)QPFDT(0.001)HLEAY(0.008)GPCLS(0.992)PPR ; 113.28 6.73E-06 0 1582.7 1446.77 1463.39 1636.55 1205.05 1769.6 1411.61 1371.83 1871.3 1306.8 TRUE FALSE FALSE 1457.427625 1571.822352 1517.624521 1629.77839 1190.680566 1402.565012 1451.215977 1790.094652 1666.023072 1352.211203 1.077810642 1.162408911 1.122328019 1.205269108 0.880543338 1.037238125 1.073216946 1.323827704 1.232073117 1 10.40110479 -13.52287875 0.143682256 0.61472355 1.140703971 0 0.131195888 118.2185559 1.173021067 12.77578583 0.295684228 3.00E-14 13.52287875 0.525980421 ESEDSETQPFDTHLEAYGPCLS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 3 ESEDSETQPFDTHLEAYGPCLSPPR 25 0 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 ESEDSETQPFDTHLEAYGPCLS(1)PPR;ESEDSETQPFDTHLEAYGPCLS(1)PPR;ESEDSETQPFDTHLEAYGPCLS(0.999)PPR ;; 166.91 4.21E-12 300849000 5828.1 3829.11 4812.16 5777.7 5205.9 6217.7 4124.22 1893.02 7716.6 5138.21 TRUE FALSE FALSE 5366.799735 4160.081206 4990.502883 5753.793408 5143.823043 4928.078932 4239.934513 2470.193084 6870.108286 5316.762415 1.009411239 0.782446324 0.938635676 1.082198706 0.967472804 0.926894705 0.797465484 0.464604752 1.292160106 1 12.37633228 -4.150618844 1.351615463 0.986345269 0.137817795 0.650055869 0.121637225 0.51288508 0.672431625 0.011229407 0.635717475 7.07E-05 4.150618844 -0.848527474 ESEEGNPVRGSEEDS(ph)PKKESK ddPTM_HeLa_Curcumin_4h_R1 1 ESEEGNPVRGSEEDSPKKESK 21 3 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 ESEEGNPVRGS(0.003)EEDS(0.702)PKKES(0.295)K 50.226 0.015566 60866000 6270 4843.2 4884 5713.8 4341.2 6045.4 4509 4881.7 6301.9 5483.8 TRUE FALSE FALSE 5773.722884 5261.824627 5065.005336 5690.15781 4289.434025 4791.515894 4635.510405 6370.107857 5610.597337 5674.361642 1.017510559 0.927298075 0.89261236 1.002783779 0.755932437 0.844414966 0.81692192 1.122612244 0.988762735 1 12.47024238 -7.129983653 3.318024772 1.008388003 0.897022091 0.16305382 0.095841018 0.276002252 5.678858425 0.015478336 0.019198239 7.41E-08 7.129983653 -0.111365913 ESEITDEDIDGILER ddPTM_HeLa_Curcumin_4h_R1 3 ESEITDEDIDGILER 15 0 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 0 0 ;; ;; 246.63 1.45E-28 39439700 6332.6 4608.93 6150.1 5794.6 6117.4 7393.6 5860.3 4787.15 6783.6 6157.8 FALSE FALSE TRUE 5831.368028 5007.305372 6378.028116 5770.623481 6044.454 5860.084017 6024.724246 6246.729998 6039.456052 6371.783092 0.915186211 0.78585622 1.000980106 0.905652844 0.948628337 0.919692954 0.945531911 0.980373925 0.94784395 1 12.63748144 -9.15873416 1.074713648 0.997151242 0.924385167 0.080797149 0.056583183 0.579198897 1.265650206 0.028903795 0.009661406 6.94E-10 9.15873416 -0.072766075 ESEKQQDS(ph)QPEEVMDVLEMVENVK ddPTM_HeLa_Curcumin_4h_R1 5 ESEKQQDSQPEEVMDVLEMVENVK 24 1 Q9H307 Q9H307 PNN Pinin 1 0 ES(0.026)EKQQDS(0.974)QPEEVMDVLEMVENVK;ES(0.03)EKQQDS(0.97)QPEEVMDVLEMVENVK;ES(0.069)EKQQDS(0.931)QPEEVMDVLEMVENVK;ES(0.142)EKQQDS(0.858)QPEEVMDVLEMVENVK;ES(0.085)EKQQDS(0.915)QPEEVMDVLEMVENVK ;;;; 62.099 0.001318 71902000 8305.76 7045.32 7467.22 7888.49 8077.69 9283.06 7889.21 9746.39 8728.42 7470.11 TRUE FALSE FALSE 7648.350332 7654.286067 7743.961742 7855.849519 7981.368822 7357.648714 8110.56 12718.01944 7770.934163 7729.695766 0.989476244 0.990244157 1.001845606 1.016320662 1.032559245 0.951867827 1.049272862 1.645345409 1.005335061 1 12.91619592 -4.262464029 4.254026994 0.996944844 1.694833713 0.989556016 0.01982258 0.012906887 0.534318974 0.002511816 0.027209128 5.46E-05 4.262464029 0.697888869 ESELTDEDITTILER ddPTM_HeLa_Curcumin_4h_R1 2 ESELTDEDITTILER 15 0 A0A0A0MRP6;B7ZLQ5;P28370-2;P28370 A0A0A0MRP6 SMARCA1 Probable global transcription activator SNF2L1 0 0 ; ; 160.86 0.0025722 1407900 1443.47 1184.55 954.76 1317.61 1426.35 1338.07 950.01 1122.92 1149.56 969.5 FALSE FALSE TRUE 1329.217826 1286.937224 990.1442455 1312.158079 1409.341708 1060.539199 976.6647238 1465.293139 1023.456144 1003.190053 1.324991035 1.282844881 0.986995677 1.307985536 1.40486013 1.057166781 0.973559019 1.46063364 1.020201647 1 9.970379233 -9.494249782 1.238589018 0.999957811 1.225787741 0.223033592 0.160161518 0.578332581 1.587259777 0.11030118 0.026810104 3.20E-10 9.494249782 0.22582993 DSAIPVESDT(ph)DDEGAPR ddPTM_HeLa_Curcumin_4h_R1 1 DSAIPVESDTDDEGAPR 17 0 C9JA08;Q96D46 C9JA08 NMD3 60S ribosomal export protein NMD3 1 0 DSAIPVES(0.495)DT(0.505)DDEGAPR 278.88 3.42E-65 123990000 4283.6 3159.4 4065.4 3856.3 3637.2 4592.5 4384.9 6122.6 4349.8 3802.9 TRUE FALSE FALSE 3944.54854 3432.484458 4216.0673 3840.343652 3593.828766 3639.963732 4507.928493 7989.352555 3872.637823 3935.050492 1.002413704 0.872284731 1.071413774 0.975932497 0.91328657 0.92501068 1.145583393 2.030304966 0.984139296 1 11.94216643 -4.263881375 3.157307728 0.985287896 2.183206356 0.9706409 0.055081618 0.038965752 0.596703895 0.00755904 0.1146173 5.45E-05 4.263881375 1.197918459 up ESEPQAAAEPAEAK ddPTM_HeLa_Curcumin_4h_R1 2 ESEPQAAAEPAEAK 14 0 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 0 0 ; ; 234.49 2.66E-37 6946100 4949.1 4087.5 4716 5736.4 5474.4 7229.2 6336.2 5662.4 6008.1 4833.1 FALSE FALSE TRUE 4557.373513 4440.805286 4890.779109 5712.664297 5409.121355 5729.78243 6513.976719 7388.839694 5349.026462 5001.049865 0.911283358 0.887974607 0.977950478 1.142293009 1.081597165 1.145715917 1.302521849 1.477457712 1.069580709 1 12.28801527 -4.061825115 0.559121115 0.952282318 1.94731669 0.861365876 0.063852707 1.012974906 0.18326107 0.011745489 0.685468898 8.67E-05 4.061825115 0.995034372 ESEQES(ph)EEEILAQKK ddPTM_HeLa_Curcumin_4h_R1 2 ESEQESEEEILAQKK 15 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 0 ES(0.217)EQES(0.783)EEEILAQKK;ES(0.001)EQES(0.999)EEEILAQKK ; 168.05 0.00031653 112694700 4282.6 3538.3 3671.6 3652.2 3909.3 4622.1 3640.47 4209.7 3771.2 3862.2 TRUE FALSE FALSE 3943.627691 3844.134886 3807.672726 3637.088164 3862.684151 3663.424358 3742.61179 5493.218151 3357.508795 3996.411163 0.986792282 0.961896744 0.952773018 0.910088581 0.966538225 0.916678542 0.936493178 1.374537786 0.840130972 1 11.9644893 -4.258234263 24.99997011 0.973394015 1.374537934 0.851536483 0.052760541 64.0556832 499611.6812 0.005371581 0.051169717 5.52E-05 4.258234263 0.401143918 ESES(ph)ESDETPPAAPQLIK ddPTM_HeLa_Curcumin_4h_R1 3 ESESESDETPPAAPQLIK 18 0 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 0 ES(0.044)ES(0.845)ES(0.11)DETPPAAPQLIK;ES(0.001)ES(0.996)ES(0.003)DETPPAAPQLIK;ES(0.024)ES(0.973)ES(0.003)DETPPAAPQLIK ;; 276.1 5.25E-67 20270800 5514.3 5294.9 6151.9 5547.4 6122.5 6011.1 4254.5 2925.48 5918.1 5077.4 TRUE FALSE FALSE 5077.837336 5752.567562 6379.894826 5524.446329 6049.493186 4764.330101 4373.86982 3817.445385 5268.899236 5253.839272 0.96650032 1.094926446 1.214330035 1.051506535 1.151442378 0.906828293 0.832509255 0.726601098 1.002866468 1 12.35915635 -4.812970378 2.412763547 1.02478402 0.755029593 0.648751238 0.082308015 0.177333301 2.004551709 0.013510476 0.06203145 1.54E-05 4.812970378 -0.269754427 ESESCDCLQGFQLTHSLGGGTGSGMGTLLISK ddPTM_HeLa_Curcumin_4h_R1 3 ESESCDCLQGFQLTHSLGGGTGSGMGTLLISK 32 0 Q9BVA1;Q13885 Q9BVA1 TUBB2B;TUBB2A Tubulin beta-2B chain;Tubulin beta-2A chain 0 0 ;; ;; 74.404 1.94E-05 35235000 1547.56 1560.21 1641.61 1472.48 1659.01 3191.55 1767.65 1868.06 2135.94 1961.19 FALSE FALSE TRUE 1425.068993 1695.0676 1702.449511 1466.387268 1639.227389 2529.586554 1817.245502 2437.622895 1901.632726 2029.341207 0.702232325 0.835279742 0.838917332 0.722592762 0.807763319 1.246506278 0.895485439 1.201189276 0.937068995 1 10.98679574 -5.279809704 24.93679796 0.839435208 1.092502847 0.531694784 0.119648034 558.9482671 758743.6006 0.019809115 0.04436751 5.25E-06 5.279809704 0.253067639 ESFDGSVR ddPTM_HeLa_Curcumin_4h_R1 1 ESFDGSVR 8 0 P19338;H7BY16 P19338 NCL Nucleolin 0 0 100.19 0.013245 2249600 2938 2592.4 2533.8 2822.8 3231.2 3416.1 2654 2547.4 2524.9 2366.9 FALSE FALSE TRUE 2705.4542 2816.475504 2627.704857 2811.120002 3192.67005 2707.562353 2728.464097 3324.090533 2247.924787 2449.149599 1.104650447 1.149981 1.072905003 1.147794321 1.30358311 1.105511217 1.114045503 1.357242749 0.917838905 1 11.25806518 -1.000000011 0.056857005 0.718244786 1.999271316 0.582847536 0.078861463 197.7618027 0.851674791 4.149624394 21.4370498 0.099999997 1.000000011 1.28102653 ESGADGASTS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 ESGADGASTSPR 12 0 O75528;O75528-2 O75528 TADA3 Transcriptional adapter 3 1 0 ESGADGAS(0.007)T(0.21)S(0.783)PR 114.87 0.00328 0 3366.8 3953.7 3587.4 3328.5 3715.8 3935 2702.8 2304 3467 3347.6 TRUE FALSE FALSE 3100.314227 4295.440211 3720.3522 3314.727549 3671.491512 3118.836643 2778.633294 3006.478994 3086.678774 3463.928851 0.895028264 1.240048626 1.074026737 0.956927146 1.059921168 0.900375492 0.802162346 0.867939015 0.891091852 1 11.75819358 -5.023185925 5.692783535 0.987910045 0.837670852 0.341925531 0.098745485 0.171692505 18.25317361 0.014850108 0.041097046 9.48E-06 5.023185925 -0.150239193 KLS(ph)GDQITLPTTVDYSSVPK ddPTM_HeLa_Curcumin_4h_R1 2 KLSGDQITLPTTVDYSSVPK 20 1 E9PJ38;E9PND3;E9PN10;O00559;O00559-2 E9PJ38 EBAG9 Receptor-binding cancer antigen expressed on SiSo cells 1 0 KLS(1)GDQITLPTTVDYSSVPK;KLS(1)GDQITLPTTVDYSSVPK ; 112.55 9.27E-05 278580000 10918.7 9242.9 9878.9 11898.3 8058.6 9874.2 4294.8 2581.7 13169.8 12412.7 TRUE FALSE FALSE 10054.47337 10041.81509 10245.02072 11849.06799 7962.506458 7826.179615 4415.300529 3368.848445 11725.10589 12844.0404 0.782812344 0.781826807 0.797647812 0.922534313 0.619937824 0.609323809 0.343762585 0.262288839 0.912882981 1 13.64881149 -4.678748548 0.572601661 0.899927593 4.72E-14 0.884884108 0.078912468 0.697395483 0.20572715 0.01913215 0.37783071 2.10E-05 4.678748548 -0.899927593 down ESGS(ph)PYSVLVDTK ddPTM_HeLa_Curcumin_4h_R1 1 ESGSPYSVLVDTK 13 0 Q9Y2D9;D6RF85 Q9Y2D9 ZNF652 Zinc finger protein 652 1 0 ES(0.018)GS(0.667)PYS(0.316)VLVDTK 135.04 0.0013149 7361100 5704.9 4347.6 4621.8 5346.8 5419.8 5952.6 5300 2212.7 6457.5 4685.1 TRUE FALSE FALSE 5253.351145 4723.387171 4793.087974 5324.676358 5355.172425 4717.96366 5448.703736 2887.342044 5749.128406 4847.906876 1.08363285 0.974314749 0.988692253 1.098345429 1.104635993 0.973196017 1.123929125 0.595585294 1.185899101 1 12.24314627 -4.254840965 24.95593014 1.040565275 0.595585088 0.789852386 0.071157563 199.6328848 755013.022 0.007546346 0.09723489 5.56E-05 4.254840965 -0.444980187 ESGVVAVS(ph)PEKSESPQKEDGLSSQLK ddPTM_HeLa_Curcumin_4h_R1 1 ESGVVAVSPEKSESPQKEDGLSSQLK 26 2 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 0 ESGVVAVS(0.376)PEKS(0.306)ES(0.306)PQKEDGLS(0.009)S(0.003)QLK 50.945 0.0050884 13236000 1595.1 1494.6 1637.7 1822.9 1928.4 2013.9 1683.3 971.1 1745.5 1714 TRUE FALSE FALSE 1468.846152 1623.786564 1698.394603 1815.357323 1905.405089 1596.194439 1730.528868 1267.18392 1554.023017 1773.561372 0.828190202 0.915551381 0.957618174 1.023566115 1.074338401 0.899993913 0.97573667 0.71448552 0.876216093 1 10.79243354 -4.2554919 24.38734087 0.938648427 0.71448538 0.497661033 0.070177385 386.4032277 1584360.45 0.011751062 0.140391724 5.55E-05 4.2554919 -0.224163047 ESGVVAVSPEKS(ph)ESPQKEDGLSSQLK ddPTM_HeLa_Curcumin_4h_R1 1 ESGVVAVSPEKSESPQKEDGLSSQLK 26 2 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 0 ESGVVAVS(0.308)PEKS(0.344)ES(0.344)PQKEDGLS(0.002)S(0.002)QLK 52.79 0.0032925 17138000 1572.8 1314.6 1424.2 1455.5 1622.9 2091.3 1656.5 1008.8 1686.1 1617.6 TRUE FALSE FALSE 1448.31122 1428.228166 1476.982105 1449.477527 1603.547977 1657.540806 1702.976932 1316.378476 1501.139048 1673.81148 0.865277385 0.853278989 0.882406485 0.865974182 0.958021854 0.990279268 1.017424574 0.786455639 0.896838782 1 10.70892133 -4.235515864 23.43415704 0.930451827 0.786455199 0.332167948 0.058770362 3733.899928 3375221.642 0.009798386 0.88668986 5.81E-05 4.235515864 -0.143996628 ESIES(ph)EIRR ddPTM_HeLa_Curcumin_4h_R1 2 ESIESEIRR 9 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 1 0 ESIES(1)EIRR;ESIES(1)EIRR ; 99.343 0.0063344 7768000 1502.51 1572.88 1607.31 1816.01 1616.19 2027.27 1659.8 1274.31 1823.09 1687.44 TRUE FALSE FALSE 1383.584748 1708.832739 1666.878323 1808.495832 1596.91799 1606.79135 1706.369521 1662.841253 1623.101588 1746.078414 0.79239554 0.978668956 0.95464116 1.035747202 0.91457404 0.920228632 0.977258242 0.952329082 0.9295697 1 10.76990263 ESIESEIRR ddPTM_HeLa_Curcumin_4h_R1 6 ESIESEIRR 9 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 ;;;;; ;;;;; 177.7 0.00012498 175070700 18855 15354.7 15766.8 15413.3 15939.8 20934.6 15961.3 15723.8 19515.9 17545.8 FALSE FALSE TRUE 17362.60685 16681.89185 16351.13148 15349.52385 15749.7283 16592.52798 16409.13112 20517.91424 17375.0546 18155.51524 0.956326858 0.918833293 0.900615117 0.845446887 0.867490021 0.913911159 0.903809718 1.130120184 0.957012476 1 14.14812025 -7.800972561 1.195029565 0.988541961 0.918632559 0.062382631 0.074051761 0.582636838 1.740584842 0.017118257 0.015732755 1.58E-08 7.800972561 -0.069909402 ESKKEDLVFIFWAPESAPLK ddPTM_HeLa_Curcumin_4h_R1 1 ESKKEDLVFIFWAPESAPLK 20 2 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;Q9Y281;Q9Y281-3 P23528;Q9Y281 CFL1;CFL2 Cofilin-1;Cofilin-2 0 0 88.264 0.00056348 25441000 3215.1 2540.1 2546.2 2938.4 1511.5 3926.4 2834.9 2392.6 3948.5 3790.1 FALSE FALSE TRUE 2960.621442 2759.654926 2640.564412 2926.241679 1493.47635 3112.02038 2914.439664 3122.092726 3515.359429 3921.805693 0.754912832 0.703669468 0.673303223 0.746146522 0.380813448 0.793517228 0.74313719 0.79608552 0.896362468 1 11.93730234 -8.642323727 0.596856752 1.006844451 0.682345777 0.423881546 0.115695574 0.504458985 0.35138084 0.080168012 0.028520056 2.28E-09 8.642323727 -0.324498675 ESLCDS(ph)PHQNLSR ddPTM_HeLa_Curcumin_4h_R1 3 ESLCDSPHQNLSR 13 0 O15042-2;O15042;E7ET15;U3KPT1;C9JDJ7;C9J5L1;E7EW00;H0Y8D9 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 1 0 ES(0.008)LCDS(0.992)PHQNLSR;ES(0.203)LCDS(0.797)PHQNLSR;ES(0.218)LCDS(0.766)PHQNLS(0.016)R ;; 120.54 0.0016819 15128600 6331.8 6124.1 6242.3 5633.4 8411.5 9244.5 8175.1 3350.82 6326.1 5504.2 TRUE FALSE FALSE 5830.631349 6653.439916 6473.645129 5610.090483 8311.198356 7327.086493 8404.471304 4372.469593 5632.142657 5695.47054 1.02373128 1.16819846 1.13663043 0.98500913 1.459264568 1.286476059 1.475641256 0.767709983 0.988881009 1 12.47559932 -6.719813444 0.881822628 1.00689589 1.239854604 0.141616781 0.197463576 0.633878103 0.985946593 0.037860467 0.062161515 1.91E-07 6.719813444 0.232958714 ESLPPAAEPS(ph)PVSK ddPTM_HeLa_Curcumin_4h_R1 2 ESLPPAAEPSPVSK 14 0 Q9NWT1 Q9NWT1 PAK1IP1 p21-activated protein kinase-interacting protein 1 1 0 ESLPPAAEPS(0.9)PVS(0.1)K;ESLPPAAEPS(0.943)PVS(0.056)K ; 130.95 0.0010608 104572000 16015.9 14067.6 15359.3 15629.6 17139.3 17764.5 14663.7 7817.3 14747.9 12205.7 TRUE FALSE FALSE 14748.22462 15283.54066 15928.52917 15564.92886 16934.92504 14079.94245 15075.12396 10200.75878 13130.09227 12629.84717 1.167727877 1.210112875 1.261181466 1.232392495 1.340865398 1.114814951 1.193610956 0.807670801 1.039608167 1 13.62454956 -8.923491703 0.854657604 1.00463636 1.176704108 0.153286874 0.134225048 0.735673662 1.020981632 0.074199295 0.026363295 1.19E-09 8.923491703 0.172067748 ESLPPAAEPS(ph)PVSKEQSK ddPTM_HeLa_Curcumin_4h_R1 2 ESLPPAAEPSPVSKEQSK 18 1 Q9NWT1 Q9NWT1 PAK1IP1 p21-activated protein kinase-interacting protein 1 1 0 ESLPPAAEPS(0.999)PVS(0.001)KEQSK;ESLPPAAEPS(1)PVSKEQSK ; 131.35 0.00010405 51089000 13349.4 11471.8 10139 12271.6 8698.3 13333.4 8390.4 6051.1 16079.6 11016.6 TRUE FALSE FALSE 12292.7809 12463.37127 10514.76026 12220.82337 8594.578454 10567.90254 8625.812042 7896.052534 14315.70811 11399.42603 1.078368408 1.093333229 0.922393832 1.072056026 0.753948351 0.927055671 0.756688277 0.692671062 1.255827098 1 13.47667356 -5.215835086 0.735819136 1.04127997 0.677418713 0.633510217 0.103268854 0.435050968 0.33023966 0.013197733 0.100629201 6.08E-06 5.215835086 -0.363861257 ESLPVSGEESQLT(ph)PEKSPK ddPTM_HeLa_Curcumin_4h_R1 1 ESLPVSGEESQLTPEKSPK 19 1 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 0 ESLPVS(0.001)GEES(0.127)QLT(0.853)PEKS(0.02)PK 87.287 0.0021926 13622000 2064.6 1889.8 2020 2090.3 1643.8 2080.6 1151.6 859.12 2205.6 2025.7 TRUE FALSE FALSE 1901.184731 2053.145891 2094.862977 2081.650892 1624.198759 1649.060107 1183.910797 1121.061733 1963.651198 2096.092924 0.907013572 0.979510912 0.999413219 0.993110023 0.774869635 0.786730439 0.564817897 0.534833986 0.936814955 1 11.03348696 -5.008693678 1.100983677 0.962899056 0.493196099 0.913085427 0.049605606 0.147091314 0.27623773 0.008393169 0.058676559 9.80E-06 5.008693678 -0.469702957 ESLS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 2 ESLSPGK 7 0 E7ETM8;Q0ZGT2-4;E7EUA0;Q0ZGT2-2;Q0ZGT2;H7BXY5 E7ETM8 NEXN Nexilin 1 0 ESLS(1)PGK;ES(0.004)LS(0.996)PGK ; 134.77 0.0053501 140750000 13637 15805.1 15680.5 14270.8 19897.1 14248.4 11267.3 12439.6 12489.9 11941.3 TRUE FALSE FALSE 12557.61706 17171.22242 16261.63312 14211.75121 19659.84008 11293.12123 11583.43011 16232.37678 11119.78922 12356.25929 1.016296014 1.389678059 1.316064413 1.150166153 1.591083484 0.913959554 0.937454439 1.313696678 0.899931683 1 13.59295443 -7.374447547 9.500189695 1.007237905 1.220877903 0.266142521 0.193478027 0.424375633 33.13484608 0.03248065 0.037097179 4.22E-08 7.374447547 0.213639997 ESLT(ph)PGREENPSSVLAQER ddPTM_HeLa_Curcumin_4h_R1 2 ESLTPGREENPSSVLAQER 19 1 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;D6RDA9;Q3MSN4 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 0 ES(0.011)LT(0.989)PGREENPSSVLAQER;ES(0.164)LT(0.836)PGREENPSSVLAQER ; 83.792 0.0029099 35356000 3294.6 2766.6 2864 3127.2 3323.4 4295.1 3511.6 2218.8 3217.1 2785.2 TRUE FALSE FALSE 3033.828934 3005.732576 2970.142359 3114.260475 3283.770626 3404.247844 3610.126045 2895.301906 2864.192179 2881.985493 1.052687094 1.042938135 1.030588935 1.080595472 1.139412615 1.181216163 1.2526524 1.004620569 0.993826022 1 11.49284736 -5.92761825 2.102161301 1.027246996 1.157476537 0.470077511 0.059855108 0.189684919 1.692470026 0.008657045 0.017404863 1.18E-06 5.92761825 0.130229541 ESLTEAEVATEKEGEDGDQPT(ph)TPPKPLK ddPTM_HeLa_Curcumin_4h_R1 1 ESLTEAEVATEKEGEDGDQPTTPPKPLK 28 2 M0R0Q7;P18858-2;P18858;P18858-3;B4E135 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 ESLTEAEVAT(0.001)EKEGEDGDQPT(0.5)T(0.5)PPKPLK 62.781 0.00072678 8884400 2590.3 2141.8 2533.7 2409.3 2554.4 2616.2 1810.2 2132 1994.5 1896 TRUE FALSE FALSE 2385.275022 2326.927648 2627.601151 2399.330955 2523.940448 2073.570629 1860.98934 2782.036985 1775.70834 1961.885859 1.215807235 1.186066783 1.339324171 1.222971736 1.286486896 1.056927252 0.948571667 1.418042223 0.905102777 1 10.93802539 -9.151459422 0.84865855 0.996740648 1.202304248 0.364913573 0.130548781 0.690138405 0.876406802 0.090168049 0.024438937 7.06E-10 9.151459422 0.2055636 ESMEAS(ph)PEAMVK ddPTM_HeLa_Curcumin_4h_R1 6 ESMEASPEAMVK 12 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 0 ES(0.016)MEAS(0.984)PEAMVK;ESMEAS(1)PEAMVK;ESMEAS(1)PEAMVK;ESMEAS(1)PEAMVK;ES(0.119)MEAS(0.881)PEAMVK;ES(0.014)MEAS(0.986)PEAMVK ;;;;; 185.57 3.92E-05 173111000 24813.2 20963.2 23303.8 22593.3 24287.4 24502.1 17124 13892.7 22769.2 19029.7 TRUE FALSE FALSE 22849.20904 22775.1656 24167.45933 22499.81491 23997.78862 19420.08826 17604.45335 18128.52028 20271.47573 19690.98066 1.160389593 1.156629321 1.227336502 1.142645727 1.218719831 0.986242819 0.894036395 0.920650961 1.029480252 1 14.26524734 -5.03373802 5.797325555 1.108719788 0.913661888 0.621607592 0.071345067 0.11976302 11.87209429 0.012713076 0.034530369 9.25E-06 5.03373802 -0.1950579 ESNCYDPER ddPTM_HeLa_Curcumin_4h_R1 1 ESNCYDPER 9 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 96.948 0.013039 2346000 2534.8 2196.1 2638.8 2179.1 2001.8 2674 1805.1 1787.1 2338.4 2257 FALSE FALSE TRUE 2334.167905 2385.921098 2736.596249 2170.083462 1977.929842 2119.382258 1855.746248 2331.978563 2081.88337 2335.430582 0.999459339 1.021619361 1.171773749 0.929200584 0.846922986 0.90749101 0.794605612 0.998521892 0.89143449 1 11.18947285 -6.010777975 24.58575555 1.015066112 0.882552773 0.376193083 0.079643269 277.6878423 633439.2734 0.009856477 0.01705716 9.75E-07 6.010777975 -0.132513339 ESNPHCGSDGQTYGNK ddPTM_HeLa_Curcumin_4h_R1 2 ESNPHCGSDGQTYGNK 16 0 Q6UWN8 Q6UWN8 SPINK6 Serine protease inhibitor Kazal-type 6 0 0 ; ; 181.75 8.08E-08 2135700 1676.26 1605.65 1264.31 1438.94 2167.4 3096.1 1538.17 1381.52 2284.8 1800.96 FALSE FALSE TRUE 1543.582252 1744.435231 1311.166441 1432.986048 2141.555171 2453.93396 1581.32691 1802.739088 2034.163156 1863.543226 0.828305043 0.936085199 0.703587887 0.768957772 1.149184597 1.316810861 0.848559287 0.967371759 1.091556733 1 10.86383257 -5.752573666 24.99993656 0.891147007 1.072224977 0.253559166 0.153250081 215.3147142 607149.4759 0.022181144 0.043837671 1.77E-06 5.752573666 0.181077971 ESNVQEVR ddPTM_HeLa_Curcumin_4h_R1 2 ESNVQEVR 8 0 P67775;P62714;E7ESG8;P67775-2 P67775 PPP2CA;PPP2CB Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform;Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform;Serine/threonine-protein phosphatase 0 0 ; ; 117.81 0.0029627 4343600 3911.3 3428.1 3404.1 3133.6 3542.2 4510.8 3016.3 3112.9 3822.9 3222 FALSE FALSE TRUE 3601.716478 3724.409689 3530.258941 3120.633993 3499.961578 3575.209233 3100.92926 4062.00888 3403.537434 3333.96426 1.080310464 1.117111462 1.05887726 0.936013031 1.049789771 1.072359796 0.93010273 1.218372053 1.020868002 1 11.70302292 -9.499763282 1.300087853 1.000542705 1.054941013 0.052413892 0.078506295 1.037848871 3.188095921 0.048564724 0.012285983 3.16E-10 9.499763282 0.054398309 ESNYFGLS(ph)PEER ddPTM_HeLa_Curcumin_4h_R1 3 ESNYFGLSPEER 12 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 0 ESNYFGLS(1)PEER;ESNYFGLS(1)PEER;ESNYFGLS(1)PEER ;; 176.56 0.00014001 82076400 9698.4 8656.7 8208 8981.8 8436.6 9884.2 6867 4929.4 9724.6 7653.1 TRUE FALSE FALSE 8930.761406 9404.946574 8512.1957 8944.635691 8335.999055 7834.105502 7059.669538 6432.351368 8657.83571 7919.044655 1.127757425 1.187636512 1.074901844 1.12950944 1.052652109 0.989274066 0.891479951 0.812263555 1.093292952 1 12.95111068 -4.767942847 1.519850229 1.078095687 0.804073822 0.799000474 0.049041082 0.236430996 0.888814685 0.009611518 0.073000441 1.71E-05 4.767942847 -0.274021866 ESNYFGLS(ph)PEERR ddPTM_HeLa_Curcumin_4h_R1 2 ESNYFGLSPEERR 13 1 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 0 ESNYFGLS(1)PEERR;ESNYFGLS(1)PEERR ; 83.891 0.0085989 34612000 7487.3 5744.5 5233.3 5699.6 5414.2 7051.2 4267.3 4133.2 7980.9 6332.2 TRUE FALSE FALSE 6894.672304 6241.028983 5427.250702 5676.016565 5349.639201 5588.701637 4387.028953 5393.393653 7105.415237 6552.243479 1.05226131 0.952502605 0.828304186 0.866270703 0.816459159 0.852944744 0.669546083 0.823136941 1.084424787 1 12.67777325 -6.818133953 1.974172574 1.025211117 0.801186543 0.79125827 0.054853982 0.104186974 0.829551204 0.009077857 0.012744911 1.52E-07 6.818133953 -0.224024574 ESPFSTSAS(ph)PLLSGSQHFDVPPR ddPTM_HeLa_Curcumin_4h_R1 1 ESPFSTSASPLLSGSQHFDVPPR 23 0 O14980 O14980 XPO1 Exportin-1 1 0 ES(0.001)PFS(0.004)T(0.005)S(0.004)AS(0.986)PLLSGSQHFDVPPR 112.32 7.56E-05 0 425.82 211.3 197.15 307.06 359.2 613.81 316.08 327.29 303.49 352.57 TRUE FALSE FALSE 392.1158977 229.5638305 204.4565524 305.7894671 354.9167746 486.4988869 324.9483541 427.0792143 270.1979063 364.8217813 1.074814931 0.629249245 0.560428579 0.838188625 0.972849739 1.333524784 0.890704368 1.170651634 0.740629864 1 8.511048056 -5.491148357 24.22890189 0.948619662 1.115143472 0.178041454 0.206846368 839.6882756 641173.3332 0.032049208 0.071587936 3.23E-06 5.491148357 0.16652381 ESPRPLQLPGAEGPAIS(ph)DGEEGGGEPGAGGGAAGAAGAGR ddPTM_HeLa_Curcumin_4h_R1 4 ESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR 40 1 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 1 0 ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR ;;; 141.82 4.20E-25 507942000 3899.21 3132.25 3347.11 3381.68 3525.89 3272.73 2859.84 1913.75 3607.71 3215.03 TRUE FALSE FALSE 3590.583414 3402.987733 3471.156841 3367.687504 3483.846065 2593.928907 2940.079414 2497.243565 3211.953239 3326.752053 1.079305989 1.022915949 1.043407139 1.01230493 1.047221437 0.779718135 0.883768723 0.750655151 0.965492224 1 11.69989863 -5.26485431 24.99653573 1.036224699 0.812619468 0.840005071 0.043677682 71.4257879 522823.0152 0.005722738 0.013302792 5.43E-06 5.26485431 -0.22360523 ESPRPLQLPGAEGPAIS(ph)DGEEGGGEPGAGGGAAGAAGAGRR ddPTM_HeLa_Curcumin_4h_R1 3 ESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGRR 41 2 Q6PKG0;A0A0B4J210 Q6PKG0 LARP1 La-related protein 1 1 0 ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGRR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGRR;ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGRR ;; 51.152 0.00093138 291253000 1858.01 1140.12 1340.5 1786.7 1451.51 2078.17 1485.3 1172.97 2578.34 1815.82 TRUE FALSE FALSE 1710.946548 1238.666893 1390.180109 1779.307109 1434.201691 1647.134116 1526.973521 1530.603153 2295.502553 1878.91961 0.910601251 0.65924422 0.739882697 0.94698416 0.763311897 0.876638951 0.812686989 0.814618755 1.221714085 1 10.87568763 -7.527554668 4.241966927 0.963081566 0.805404655 0.462789178 0.110452882 0.13008328 5.254567251 0.013805423 0.014964632 2.97E-08 7.527554668 -0.157676911 ESPS(ph)PAPKPR ddPTM_HeLa_Curcumin_4h_R1 1 ESPSPAPKPR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 ES(0.001)PS(0.999)PAPKPR 95.358 0.0068448 29502000 1431.7 1065.5 1339.1 1332.4 1230.6 1425.8 1135.8 2969.8 1457.9 1387 TRUE FALSE FALSE 1318.379434 1157.597072 1388.728224 1326.886882 1215.925899 1130.073008 1167.667491 3875.278349 1297.972017 1435.198147 0.918604471 0.806576482 0.967621249 0.924532187 0.847218136 0.787398598 0.813593227 2.70016956 0.904385238 1 10.48703422 -4.259322367 24.99994592 0.921817434 2.70017017 0.981003399 0.075603314 20.67474279 244132.014 0.012333865 0.108637036 5.50E-05 4.259322367 1.778352736 ESPSSTT(ph)PPIEISSSR ddPTM_HeLa_Curcumin_4h_R1 1 ESPSSTTPPIEISSSR 16 0 Q9HC44 Q9HC44 GPBP1L1 Vasculin-like protein 1 1 0 ESPSS(0.004)T(0.031)T(0.729)PPIEIS(0.009)S(0.222)S(0.004)R 137.39 0.0012001 7136300 1720.3 1690.8 1562.8 1813.8 1766.6 2675.4 2201.2 1125.8 1923 1426.7 TRUE FALSE FALSE 1584.13644 1836.945218 1620.718743 1806.294976 1745.534449 2120.491882 2262.959748 1469.051237 1712.051711 1476.277719 1.073061267 1.244308706 1.097841363 1.223546866 1.182388941 1.436377353 1.532882139 0.995104931 1.159708427 1 10.52774843 -6.697807393 0.548744136 1.012186803 1.330206309 0.201898587 0.149319731 0.590198711 0.374426617 0.039309246 0.074538089 2.01E-07 6.697807393 0.318019506 ESPSVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 ESPSVKR 7 1 Q02078-3;Q02078-5;Q02078;Q02078-8;Q02078-7;Q02078-4;Q02078-6;Q02078-2;Q06413-5;A0A0D9SGI5;Q06413-6;A0A0D9SFD0;A0A0D9SGF3;A0A1B0GV32;A0A0R4J2G5;D8L7E9;Q06413-4;Q06413-3;Q06413-2;Q06413 Q02078-3;Q02078-8;Q06413-5 MEF2A;MEF2C Myocyte-specific enhancer factor 2A;Myocyte-specific enhancer factor 2C 0 1 ; ESPSVK(1)R;ESPSVK(1)R 110.81 0.0045046 27309000 4728 4649.6 5203.2 4083.2 4073.2 5875.3 3294.7 2049.35 3727.1 4021.7 FALSE TRUE FALSE 4353.773811 5051.490706 5396.035169 4066.3048 4024.62975 4656.696552 3387.140415 2674.187381 3318.246455 4161.453776 1.046214627 1.213876443 1.296670697 0.97713564 0.967121099 1.119007155 0.813932005 0.642608936 0.797376742 1 12.0228719 -4.570160027 3.429078696 1.053623192 0.663578629 0.509310023 0.131699283 0.119249239 2.748690541 0.015720927 0.082035658 2.69E-05 4.570160027 -0.390044563 ESQLAHIKDEPPPLS(ph)PAPLTPATPSSLDPFFSR ddPTM_HeLa_Curcumin_4h_R1 2 ESQLAHIKDEPPPLSPAPLTPATPSSLDPFFSR 33 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 ESQLAHIKDEPPPLS(0.987)PAPLT(0.012)PAT(0.001)PSSLDPFFSR;ESQLAHIKDEPPPLS(0.641)PAPLT(0.341)PAT(0.014)PS(0.002)S(0.002)LDPFFSR ; 84.221 4.07E-08 295090000 4449.5 4118.4 4296.9 4178.1 5094.2 7986.1 5848.4 4938.7 5749.5 4382.5 TRUE FALSE FALSE 4097.31738 4474.376145 4456.146894 4160.812129 5033.454992 6329.692838 6012.490364 6444.486895 5118.794235 4534.791549 0.903529376 0.986677358 0.982657493 0.917531067 1.109963917 1.395806791 1.325858157 1.421120866 1.128782697 1 12.14682052 -5.427798155 2.891412426 0.956361872 1.378383209 0.872169245 0.066707779 0.041377813 0.666024417 0.006629545 0.016156639 3.73E-06 5.427798155 0.422021338 ESRPGLVTVTSSQST(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 2 ESRPGLVTVTSSQSTPAK 18 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 0 ESRPGLVTVTSSQS(0.009)T(0.991)PAK;ESRPGLVTVTSSQS(0.046)T(0.954)PAK ; 166.34 1.30E-05 28280000 6325.2 5496.5 6304.7 5404.2 7287.3 8218.7 4761.8 1494.36 5754 4370.2 TRUE FALSE FALSE 5824.553746 5971.592968 6538.357728 5381.838852 7200.403707 6514.048976 4895.403292 1949.983485 5122.800596 4522.064125 1.288029887 1.32054584 1.445879038 1.190128823 1.59228253 1.440503451 1.082559459 0.431215355 1.132845633 1 12.14276573 -4.289123254 3.621032832 1.227641513 0.363423683 0.679000233 0.174012711 0.142350483 3.367111546 0.029575068 0.316603586 5.14E-05 4.289123254 -0.86421783 ESRQESDPEDDDVKKPALQS(ph)SVVATSK ddPTM_HeLa_Curcumin_4h_R1 2 ESRQESDPEDDDVKKPALQSSVVATSK 27 3 Q9H307 Q9H307 PNN Pinin 1 0 ESRQES(0.004)DPEDDDVKKPALQS(0.92)S(0.074)VVAT(0.001)SK;ES(0.215)RQES(0.211)DPEDDDVKKPALQS(0.283)S(0.283)VVAT(0.005)S(0.003)K ; 90.545 3.31E-06 385020000 10334.7 7547.3 6604 8407.4 6322.9 9934.4 7923.1 5493.8 10889.6 9603 TRUE FALSE FALSE 9516.69759 8199.654982 6848.750049 8372.612406 6247.503547 7873.893456 8145.400862 7168.83433 9695.038124 9936.703535 0.957731863 0.825188651 0.689237636 0.842594566 0.628729993 0.792404989 0.819728679 0.721449956 0.975679519 1 13.27855161 -7.185221303 2.617313113 0.982363162 0.752576193 0.745428432 0.059703971 0.09281893 1.22554078 0.009821183 0.011976305 6.53E-08 7.185221303 -0.229786969 ESRS(ph)PQQSAALPR ddPTM_HeLa_Curcumin_4h_R1 3 ESRSPQQSAALPR 13 1 A0A0A6YYG7;Q6IBW4-2;Q6IBW4;Q6IBW4-4;E5RJN3 A0A0A6YYG7 NCAPH2 Condensin-2 complex subunit H2 1 0 ES(0.008)RS(0.987)PQQS(0.005)AALPR;ES(0.174)RS(0.826)PQQSAALPR;ES(0.149)RS(0.851)PQQSAALPR ;; 142.12 0.00039353 160555900 3143.3 2398.26 2552.63 2944.97 3029.05 2985.52 2315.74 2059.05 3262.09 2636.74 TRUE FALSE FALSE 2894.504488 2605.554908 2647.232713 2932.784494 2992.930557 2366.289498 2380.713432 2686.844866 2904.246888 2728.366519 1.060892834 0.954987129 0.970262864 1.074923209 1.096967924 0.867291649 0.872578305 0.984781498 1.064463615 1 11.41382175 -5.251824335 24.988164 1.026685916 0.904653262 0.534398742 0.052673821 414.7471189 1077867.4 0.007527102 0.018934393 5.60E-06 5.251824335 -0.122032653 ESS(ph)LDGLGGTGK ddPTM_HeLa_Curcumin_4h_R1 1 ESSLDGLGGTGK 12 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 0 ES(0.002)S(0.998)LDGLGGTGK 129.37 0.00176 0 1684.4 1215.7 1477.7 1427.3 1925 3114.8 3773.5 1961.4 1690.1 1307.8 TRUE FALSE FALSE 1551.077963 1320.779691 1532.464862 1421.394211 1902.045632 2468.755369 3879.374254 2559.421831 1504.700258 1353.245953 1.146190727 0.976008602 1.132436316 1.050359107 1.405543189 1.824321266 2.866717795 1.891320514 1.111919275 1 10.40220836 -5.204826988 2.123171907 1.070574377 2.379090324 0.815290818 0.244534501 0.081032013 0.700432925 0.031168724 0.099863331 6.24E-06 5.204826988 1.308515946 ESS(ph)PEKEAEEGCPEK ddPTM_HeLa_Curcumin_4h_R1 2 ESSPEKEAEEGCPEK 15 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 ES(0.154)S(0.846)PEKEAEEGCPEK;ES(0.166)S(0.834)PEKEAEEGCPEK ; 127.3 0.0073937 23736100 4152.2 4084.9 4298.3 3819.1 4915.4 4456 4003.2 4123.9 3103.7 2989.1 TRUE FALSE FALSE 3823.548989 4437.980554 4457.598779 3803.297576 4856.787065 3531.775371 4115.519018 5381.258126 2763.231875 3092.971003 1.236205896 1.434860059 1.4412029 1.229658336 1.570265955 1.141871478 1.330603816 1.739834651 0.893390812 1 11.59477759 -11.99280002 0.106322068 1.12E-10 1.679438852 0.571709717 0.15961892 44.03207006 0.496634132 10.84068921 1.264358691 1.02E-12 11.99280002 1.679438851 ESS(ph)PEKEAEEGCPEKESEEGCPK ddPTM_HeLa_Curcumin_4h_R1 3 ESSPEKEAEEGCPEKESEEGCPK 23 2 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 ES(0.168)S(0.832)PEKEAEEGCPEKESEEGCPK;ES(0.102)S(0.877)PEKEAEEGCPEKES(0.02)EEGCPK;ES(0.209)S(0.79)PEKEAEEGCPEKES(0.001)EEGCPK ;; 71.091 0.00045934 402067000 4498.6 3510.66 4339 3967.09 4574.6 4840.2 3753.95 3165.91 4264.31 3406.26 TRUE FALSE FALSE 4142.531063 3814.105807 4499.807157 3950.675233 4520.050883 3836.28796 3859.275734 4131.181385 3796.525862 3524.627281 1.17531039 1.082130252 1.276676028 1.120877448 1.282419536 1.088423726 1.09494577 1.172090282 1.077142506 1 11.78325499 -9.250074415 0.726618042 0.986352043 1.163107725 0.299283848 0.071572732 0.599162171 0.499626853 0.064803867 0.013316856 5.62E-10 9.250074415 0.176755682 INFS(ph)DLDQR ddPTM_HeLa_Curcumin_4h_R1 3 INFSDLDQR 9 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 0 INFS(1)DLDQR;INFS(1)DLDQR;INFS(1)DLDQR ;; 132.86 0.0034691 35206700 11859.3 10993.1 10552.3 11106.5 11237.5 12134.8 4293.26 1149.44 11659.3 10833.8 TRUE FALSE FALSE 10920.62389 11943.29458 10943.37752 11060.54425 11103.50015 9617.905693 4413.717321 1499.898965 10380.30396 11210.27374 0.974162107 1.065388308 0.976191819 0.986643547 0.990475381 0.857954579 0.393720744 0.133796819 0.925963469 1 13.45253389 -4.677387941 2.012573753 0.993556194 0.118330138 0.986245132 0.03442914 0.023511798 0.1673906 0.004082497 0.0277651 2.10E-05 4.677387941 -0.875226056 down ESS(ph)PIPS(ph)PTSDRK ddPTM_HeLa_Curcumin_4h_R1 3 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 2 0 ES(0.025)S(0.975)PIPS(0.989)PT(0.006)S(0.005)DRK;ES(0.007)S(0.993)PIPS(0.958)PT(0.018)S(0.024)DRK;ES(0.057)S(0.943)PIPS(0.777)PT(0.046)S(0.176)DRK ;; 180.95 0.00021057 222731000 26585.9 23425.2 26087.8 25254.9 26068 30998 22336.4 19705.2 25501.2 23631.5 TRUE FALSE FALSE 24481.59796 25449.96991 27054.63682 25150.40192 25757.15613 24568.66538 22963.09927 25713.22477 22703.78216 24452.69287 1.001182082 1.040783935 1.106407256 1.028533015 1.053346405 1.00474273 0.939082636 1.051549819 0.928477787 1 14.57770573 -3.913845366 21.02594468 1.012329211 3.593693471 0.055988672 0.04933079 1780.974905 436637.7404 0.00591903 1004.588331 0.000121942 3.913845366 2.58136426 ESS(ph)PIPSPTSDR ddPTM_HeLa_Curcumin_4h_R1 1 ESSPIPSPTSDR 12 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 ES(0.028)S(0.971)PIPS(0.001)PTSDR 100.04 0.0092789 14371000 1224.4 1456 1273.6 1353.3 1363.4 1700.9 1234.9 1890.8 1537.3 1294.3 TRUE FALSE FALSE 1127.487448 1581.850152 1320.800736 1347.700403 1347.142345 1348.114167 1269.54797 2467.296216 1368.662036 1339.276829 0.84186288 1.181122617 0.986204426 1.006289644 1.005872958 1.00659859 0.94793544 1.842260064 1.0219411 1 10.38723848 -4.260868863 24.96229247 0.96236151 1.842260337 0.894450871 0.085964629 11.05612436 483623.9708 0.013464032 0.107219483 5.48E-05 4.260868863 0.879898826 TAMPSPGVS(ph)QNK ddPTM_HeLa_Curcumin_4h_R1 2 TAMPSPGVSQNK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 0 TAMPS(0.042)PGVS(0.958)QNK;T(0.009)AMPS(0.208)PGVS(0.783)QNK ; 128.36 0.003128 20822600 9458.2 7443.1 8132.4 8401.7 8730.9 8109.2 7963.9 12275.6 7378.5 6049.9 TRUE FALSE FALSE 8709.57349 8086.448398 8433.793898 8366.935992 8626.78972 6427.26051 8187.3456 16018.37393 6569.09701 6260.133575 1.391275983 1.291737357 1.347222675 1.336542726 1.37805202 1.026697024 1.307854777 2.558791077 1.049354128 1 12.61197773 -4.26383737 4.855994007 1.222113663 2.628382096 0.885475526 0.142894444 0.048304739 3.325851254 0.023981877 0.227861649 5.45E-05 4.26383737 1.406268433 up RASS(ph)PGYIDSPTYSR ddPTM_HeLa_Curcumin_4h_R1 1 RASSPGYIDSPTYSR 15 1 A0A0C4DGA7;O94929-2;O94929-3;O94929 A0A0C4DGA7 ABLIM3 Actin-binding LIM protein 3 1 0 RAS(0.01)S(0.981)PGY(0.002)IDS(0.001)PT(0.006)YSR 121.95 0.0018527 4176000 1665.1 1133.8 1377.3 1251.7 938.06 1482.3 993.41 554.24 1902.8 1656.4 TRUE FALSE FALSE 1533.305578 1231.80062 1428.34395 1246.520797 926.8742472 1174.854271 1021.282411 723.2252246 1694.067601 1713.959777 0.894598344 0.718687006 0.833359084 0.727275409 0.540779463 0.685461985 0.595861364 0.421961609 0.988394024 1 10.74311754 -4.676054549 0.211042905 1.055021988 0.071747884 0.868173608 0.065667724 2.553305096 0.119396053 0.077550466 0.670634794 2.11E-05 4.676054549 -0.983274104 down ESS(ph)PLSSR ddPTM_HeLa_Curcumin_4h_R1 1 ESSPLSSR 8 0 A0A0A0MS66;Q14693-6;Q14693;Q14693-2;Q14693-4;Q14693-3;Q14693-5;Q14693-7 A0A0A0MS66 LPIN1 Phosphatidate phosphatase LPIN1 1 0 ES(0.137)S(0.863)PLSSR 104.01 0.013044 10457000 4151 3283 3412.6 3505.3 3466.3 3962.3 2813.7 2046.7 3912.9 3590.1 TRUE FALSE FALSE 3822.44397 3566.767891 3539.073958 3490.795997 3424.966636 3140.474316 2892.644849 2670.729408 3483.66466 3714.855708 1.028961626 0.960136321 0.952681406 0.939685488 0.921964918 0.845382584 0.778669503 0.718932206 0.937765807 1 11.85909046 -4.494294384 0.49247179 1.014351504 0.546552566 0.902637204 0.028984816 0.447128585 0.084044921 0.004449522 0.11542778 3.20E-05 4.494294384 -0.467798938 ESS(ph)PLYS(ph)PTFSDSTSAVK ddPTM_HeLa_Curcumin_4h_R1 4 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 ES(0.008)S(0.992)PLYS(0.976)PT(0.01)FS(0.01)DS(0.003)T(0.001)SAVK;ES(0.07)S(0.93)PLYS(0.81)PT(0.146)FS(0.026)DS(0.003)T(0.012)S(0.002)AVK;ES(0.083)S(0.917)PLY(0.005)S(0.976)PT(0.01)FS(0.008)DS(0.001)TSAVK;ES(0.061)S(0.939)PLYS(0.869)PT(0.057)FS(0.074)DSTSAVK ;;; 199.05 2.87E-09 483074200 31247.9 26455.9 28625.9 32548 30720.4 27708.1 23639 37365.7 33756.7 27276.3 TRUE FALSE FALSE 28774.59574 28742.63011 29686.80104 32413.325 30354.07929 21961.12773 24302.24672 48758.32992 30053.67447 28224.14939 1.019502673 1.01837011 1.051822701 1.148425221 1.075464804 0.778097062 0.861044433 1.727539393 1.064821265 1 14.78464248 -4.254496382 24.98568313 1.003715015 1.727539731 0.820187609 0.101918408 252.6725074 909266.3557 0.014175574 0.189325477 5.57E-05 4.254496382 0.723824716 ESS(ph)PLYS(ph)PTFSDSTSAVKEK ddPTM_HeLa_Curcumin_4h_R1 1 ESSPLYSPTFSDSTSAVKEK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 ES(0.176)S(0.803)PLY(0.368)S(0.607)PT(0.039)FS(0.007)DSTSAVKEK 96.128 0.00057025 11614000 1904.3 1217.9 1066.8 1435.4 669.72 1561.9 852.28 1913.9 3116 2017.9 TRUE FALSE FALSE 1753.572646 1323.169849 1106.336546 1429.460695 661.7340264 1237.944334 876.192683 2497.439299 2774.182596 2088.021875 0.839824844 0.633695396 0.529849117 0.68460044 0.316919106 0.592879006 0.419628115 1.196079088 1.328617592 1 11.02792111 -7.494685808 1.344588449 0.949834251 0.596651108 0.361173226 0.251716655 0.317828137 1.142230311 0.04346631 0.046691681 3.20E-08 7.494685808 -0.353183143 ESS(ph)PLYSPTFSDSTSAVK ddPTM_HeLa_Curcumin_4h_R1 5 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 ES(0.013)S(0.986)PLYS(0.001)PTFSDSTSAVK;ES(0.006)S(0.994)PLYSPTFSDSTSAVK;ES(0.007)S(0.993)PLYSPTFSDSTSAVK;ES(0.005)S(0.995)PLYSPTFSDSTSAVK;ES(0.099)S(0.894)PLY(0.001)S(0.006)PTFSDSTSAVK ;;;; 322.68 6.58E-115 1633723000 12881.9 11295.8 11111.5 11421.1 11468 11857.6 7105.7 5719.7 13485 10384.4 TRUE FALSE FALSE 11862.28402 12272.15862 11523.30196 11373.84251 11331.25159 9398.200097 7305.066818 7463.6102 12005.72924 10745.25713 1.103955343 1.142100042 1.07240821 1.058498869 1.054535174 0.87463706 0.679841044 0.694595775 1.117304974 1 13.39141239 -5.001779825 2.287107443 1.060920581 0.678958262 0.936606129 0.040894346 0.065064902 0.662903631 0.007311887 0.027476029 9.96E-06 5.001779825 -0.381962319 ESS(ph)PSHGLLK ddPTM_HeLa_Curcumin_4h_R1 1 ESSPSHGLLK 10 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 0 ES(0.21)S(0.771)PS(0.02)HGLLK 92.112 0.008416 5793800 4350.3 3542.4 3603.6 3502.3 5131.3 6824.8 3242 1442.6 5102.5 4141.5 TRUE FALSE FALSE 4005.969165 3848.589271 3737.152586 3487.808411 5070.112599 5409.259549 3332.961795 1882.442099 4542.768516 4285.416817 0.934791022 0.898066498 0.872062799 0.813878453 1.183108392 1.262248173 0.777745068 0.439266979 1.060052898 1 12.06521982 -4.40521634 3.743593171 0.977550173 0.446596934 0.61817575 0.135069448 0.124887175 2.814590469 0.018833178 0.136484209 3.93E-05 4.40521634 -0.530953239 ESSAMAS(ph)PLPR ddPTM_HeLa_Curcumin_4h_R1 1 ESSAMASPLPR 11 0 Q9C0C2;E9PKK0;E9PKE7 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 ESSAMAS(1)PLPR 123.26 0.0037753 20169000 2819.4 2399.9 2906 2745.8 2149.3 2506.7 2018.5 912.68 2885.3 2152.4 TRUE FALSE FALSE 2596.241515 2607.336662 3013.698916 2734.438607 2123.671001 1986.782164 2075.133677 1190.951931 2568.789809 2227.19574 1.165699749 1.170681416 1.353136082 1.227749568 0.953517898 0.89205548 0.931724877 0.534731595 1.153374067 1 11.12101264 -3.979781495 0.871687984 1.112634557 1.07E-10 0.723328257 0.114878312 1.68179324 0.680675917 0.02116197 2.001972104 0.000104766 3.979781495 -1.112634557 ESSANNSVS(ph)PSESLR ddPTM_HeLa_Curcumin_4h_R1 4 ESSANNSVSPSESLR 15 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 0 ESSANNS(0.001)VS(0.367)PS(0.367)ES(0.265)LR;ESSANNS(0.059)VS(0.681)PS(0.259)ESLR;ESSANNS(0.012)VS(0.985)PS(0.003)ES(0.001)LR;ESS(0.003)ANNS(0.225)VS(0.772)PSESLR ;;; 273.54 1.23E-51 1186880000 9116.2 7063 7100.1 7994.7 8318.1 8179.7 6290.2 5130.79 8797.1 7661.5 TRUE FALSE FALSE 8394.643151 7673.494248 7363.235952 7961.62005 8218.91209 6483.138016 6466.686083 6695.144252 7832.080139 7927.736555 1.058895322 0.967930026 0.928794228 1.004274044 1.03672871 0.817779195 0.815703958 0.844521536 0.987933956 1 12.95269331 -5.258753161 24.98502195 1.014890292 0.82497179 0.814900755 0.036894511 74.02485924 688514.0937 0.006134829 0.014891201 5.51E-06 5.258753161 -0.189918502 ESSIIAPAPAEDVDT(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 4 ESSIIAPAPAEDVDTPPR 18 0 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 0 ESSIIAPAPAEDVDT(1)PPR;ESSIIAPAPAEDVDT(1)PPR;ESS(0.002)IIAPAPAEDVDT(0.998)PPR;ESSIIAPAPAEDVDT(1)PPR ;;; 229.96 3.55E-23 279650000 12150.9 10032 10898.2 10532.5 12918 13069.7 11293.8 9484.1 10800.5 9768.4 TRUE FALSE FALSE 11189.14344 10899.12138 11302.09688 10488.91931 12763.96129 10358.89689 11610.67363 12375.75843 9615.712172 10107.85117 1.106975484 1.078282732 1.118150306 1.037700212 1.262776931 1.024836705 1.148678728 1.22437086 0.951311214 1 13.30318871 -13.52287875 0.071050752 0.544522389 1.291039729 0.46646771 0.067974551 161.7875893 0.89188968 12.19087316 1.707761277 3.00E-14 13.52287875 0.74651734 ESSIIAPAPAEDVDT(ph)PPRK ddPTM_HeLa_Curcumin_4h_R1 2 ESSIIAPAPAEDVDTPPRK 19 1 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 0 ESSIIAPAPAEDVDT(1)PPRK;ESSIIAPAPAEDVDT(1)PPRK ; 131.86 8.60E-05 22795200 9045.5 7330.8 7627 8099.9 8173.5 9712.1 7420.1 7485.5 9030.8 7420.5 TRUE FALSE FALSE 8329.53913 7964.441687 7909.663329 8066.38476 8076.036351 7697.700982 7628.288036 9767.794491 8040.143834 7678.361823 1.084806802 1.03725793 1.030123809 1.050534599 1.051791585 1.002518657 0.993478585 1.27211959 1.047117083 1 12.90658283 -1.000733487 0.008127902 0.029481112 2.197892831 0.116086697 0.071958389 31879.55181 20.25894575 2398.136757 3043.114554 0.099831251 1.000733487 2.168411719 ESSIIAPAPAEDVDT(ph)PPRKK ddPTM_HeLa_Curcumin_4h_R1 2 ESSIIAPAPAEDVDTPPRKK 20 2 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 0 ESSIIAPAPAEDVDT(1)PPRKK;ESSIIAPAPAEDVDT(1)PPRKK ; 66.977 0.0033739 36253000 10951.6 8142.3 8582.4 9680.9 7225.7 12246.5 8737.3 8314.9 12824.7 10630.1 TRUE FALSE FALSE 10084.7693 8846.084131 8900.471294 9640.843001 7139.538247 9706.437853 8982.445123 10850.07473 11417.8625 10999.49518 0.916839285 0.804226374 0.809170889 0.876480497 0.649078719 0.882443939 0.816623397 0.986415699 1.038035138 1 13.42514969 -7.726451331 1.15118226 0.978441136 0.826638416 0.41526963 0.083812099 0.302994503 0.83570538 0.01852737 0.017590614 1.88E-08 7.726451331 -0.15180272 HSAS(ph)PVVFTSAR ddPTM_HeLa_Curcumin_4h_R1 1 HSASPVVFTSAR 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 HS(0.002)AS(0.998)PVVFTSAR 152.11 0.00020205 27143000 4533.2 3523.7 3435.4 3218 3477.8 4464.1 1608.7 675.86 4210.4 2963.5 TRUE FALSE FALSE 4174.392437 3828.272927 3562.718946 3204.684769 3436.329506 3538.195339 1653.835792 881.9266027 3748.529654 3066.481404 1.361297163 1.248425287 1.161826366 1.045069037 1.120609928 1.153829054 0.539326862 0.287602136 1.222420475 1 11.58236849 -4.671888457 3.086293649 1.167955406 0.321653256 0.904865933 0.098792192 0.073447103 1.337150101 0.020128763 0.096324908 2.13E-05 4.671888457 -0.846302151 down ESSPIPS(ph)PTSDR ddPTM_HeLa_Curcumin_4h_R1 1 ESSPIPSPTSDR 12 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 ESS(0.001)PIPS(0.654)PT(0.323)S(0.022)DR 124.51 0.0031037 29042000 5811.9 4833.4 4610.1 4763.4 4848 6395.1 3412 4668.6 6314.8 4784.1 TRUE FALSE FALSE 5351.881982 5251.177559 4780.954361 4743.690313 4790.190766 5068.684172 3507.731537 6092.034648 5622.082239 4950.347119 1.081112466 1.060769565 0.96578164 0.958254078 0.96764745 1.023904799 0.708582944 1.230627773 1.135694549 1 12.27331398 -6.751134355 23.56624725 1.041058326 0.964672029 0.100656721 0.12349435 189.9805919 434457.7796 0.017159844 0.024091116 1.77E-07 6.751134355 -0.076386297 ESSPIPS(ph)PTSDRK ddPTM_HeLa_Curcumin_4h_R1 1 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 ESS(0.001)PIPS(0.741)PT(0.129)S(0.129)DRK 164.92 0.00027819 13940000 2832.5 2729.9 2410.7 2297.1 2825.4 2953 1875.6 2421.6 3170.1 2393.4 TRUE FALSE FALSE 2608.304636 2965.860392 2500.042663 2287.595209 2791.70895 2340.514513 1928.224288 3159.934692 2822.347961 2476.570472 1.053192173 1.197567534 1.0094777 0.923694777 1.127247935 0.945062755 0.778586481 1.275931668 1.139619483 1 11.27412796 -6.539140843 24.98471802 1.041838245 0.996781979 0.026612243 0.136478547 851.0577102 1307541.472 0.019740496 0.027921445 2.89E-07 6.539140843 -0.045056267 ESSPLY(ph)SPTFSDSTSAVK ddPTM_HeLa_Curcumin_4h_R1 1 ESSPLYSPTFSDSTSAVK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 ES(0.034)S(0.16)PLY(0.798)S(0.007)PT(0.001)FSDSTSAVK 106.79 0.0057844 30060000 2530.5 1763.5 2368.2 1876.6 1854.3 2469.6 1350.8 926.24 2620.5 1937.1 TRUE FALSE FALSE 2330.208255 1915.929082 2455.967575 1868.835126 1832.188684 1957.377122 1388.699813 1208.646312 2333.037706 2004.414081 1.162538358 0.955854931 1.225279546 0.932359807 0.914076937 0.976533312 0.692820823 0.602992328 1.163949968 1 10.96896486 -4.416346529 0.729774708 1.075185792 0.345798225 0.750662807 0.094283919 0.850302514 0.362045464 0.015938103 0.484739778 3.83E-05 4.416346529 -0.729387567 NS(ph)SSPVSPASVPGQR ddPTM_HeLa_Curcumin_4h_R1 1 NSSSPVSPASVPGQR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 0 NS(0.461)S(0.461)S(0.072)PVS(0.005)PASVPGQR 110.22 0.0022071 21119000 4082.8 3398.4 3510 3714.4 3583.1 3623.7 2161 1100.4 4262.1 3396.7 TRUE FALSE FALSE 3759.642072 3692.142553 3640.083688 3699.030797 3540.373873 2872.103772 2221.631844 1435.906894 3794.558293 3514.735072 1.069680074 1.050475349 1.035663745 1.052435168 1.007294661 0.817160814 0.63209084 0.408539154 1.079614314 1 11.77920023 -4.670081871 1.241121336 1.038474781 0.335732966 0.98484965 0.026533139 0.074342551 0.152702423 0.004711925 0.05513588 2.14E-05 4.670081871 -0.702741815 down ESSRK(ac)GWESR ddPTM_HeLa_Curcumin_4h_R1 1 ESSRKGWESR 10 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 0 1 ESSRK(1)GWESR 67.334 0.019904 605020 1404.9 923.31 1018.7 1282.3 720.03 1377 1032.7 1151.3 1861 1699.4 FALSE TRUE FALSE 1293.700683 1003.116802 1056.453918 1276.994182 711.4441125 1091.394678 1061.674783 1502.32607 1656.852956 1758.454024 0.735703445 0.570453813 0.600785636 0.72620277 0.404584995 0.620655794 0.603754644 0.854344811 0.942221368 1 10.7800919 -8.386367921 0.662638105 0.988371996 0.615718444 0.586251088 0.112071189 0.320821562 0.299593654 0.055827707 0.027338216 4.11E-09 8.386367921 -0.372653552 ESSTSEGADQKMS(ph)S(ph)PEDDSDTKR ddPTM_HeLa_Curcumin_4h_R1 4 ESSTSEGADQKMSSPEDDSDTKR 23 2 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 2 0 ESSTS(0.001)EGADQKMS(0.999)S(0.999)PEDDSDTKR;ESSTSEGADQKMS(0.999)S(0.999)PEDDSDTKR;ESS(0.002)T(0.002)S(0.002)EGADQKMS(0.976)S(0.955)PEDDS(0.024)DT(0.04)KR;ES(0.043)S(0.374)T(0.22)S(0.255)EGADQKMS(0.549)S(0.549)PEDDS(0.007)DT(0.004)KR ;;; 92.133 0.00016513 187863000 23777.8 18395.1 21204.2 23647.9 22300.8 25641.2 22434.6 24408.7 24203.6 20878.5 TRUE FALSE FALSE 21895.76204 19985.09048 21990.04631 23550.05126 22034.87753 20322.92608 23064.0545 31850.80027 21548.52563 21604.02632 1.013503766 0.925063235 1.017867965 1.090076956 1.019943098 0.940700857 1.0675813 1.474299271 0.997431003 1 14.39901259 -4.270090031 3.651708329 1.00480642 1.522164495 0.915091973 0.043005038 0.050474249 1.233715782 0.005806344 0.069916196 5.37E-05 4.270090031 0.517358075 ESSTSEGADQKMS(ph)SPEDDSDTKR ddPTM_HeLa_Curcumin_4h_R1 1 ESSTSEGADQKMSSPEDDSDTKR 23 2 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 0 ESSTS(0.002)EGADQKMS(0.642)S(0.349)PEDDS(0.003)DT(0.003)KR 64.331 0.0011348 43481000 2683.4 1848.5 1769 2113.1 2401.5 2786.5 1929.5 1636.3 2939.4 2253.9 TRUE FALSE FALSE 2471.006058 2008.276103 1834.560696 2104.356552 2372.863681 2208.54849 1983.636577 2135.200337 2616.955174 2332.222857 1.059506835 0.861099572 0.786614663 0.902296513 1.017425789 0.946971462 0.850534747 0.915521572 1.122086239 1 11.18748994 -7.262877882 24.99890548 1.028100451 0.897893696 0.547895596 0.066042188 84.40512455 1466822.445 0.011002656 0.012950085 5.46E-08 7.262877882 -0.130206755 ASEIGEK(ac)YR ddPTM_HeLa_Curcumin_4h_R1 1 ASEIGEKYR 9 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 0 1 ASEIGEK(1)YR 91.867 0.0182 6366200 2270.1 1317.3 1538 1887.1 1590.6 1867.8 1029.5 269.17 2366.1 1915.2 FALSE TRUE FALSE 2090.41919 1431.161542 1594.999633 1879.29168 1571.633134 1480.397226 1058.384999 351.2386939 2106.54475 1981.753057 1.054833336 0.722169463 0.804842776 0.948297606 0.793051954 0.747013973 0.534065027 0.177236358 1.062970354 1 10.95256149 -4.5509901 0.612968079 1.000249117 4.38E-39 0.814850372 0.11064063 0.803803402 0.253864229 0.021671451 0.525782088 2.81E-05 4.5509901 -1.000249117 down EST(ph)PLASGPSSFQR ddPTM_HeLa_Curcumin_4h_R1 1 ESTPLASGPSSFQR 14 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 0 ES(0.116)T(0.878)PLAS(0.006)GPSSFQR 118.73 0.0054944 22710000 1226.2 1059.4 985.69 1249.1 1331.8 1982.3 2001.1 959.61 1332.2 1133.2 TRUE FALSE FALSE 1129.144976 1150.969815 1022.220539 1243.931555 1315.919155 1571.148635 2057.24548 1252.190671 1186.060993 1172.578616 0.962958868 0.981571555 0.871771432 1.060851305 1.122243863 1.339908995 1.754462731 1.067894856 1.011498058 1 10.19546894 -5.388541546 2.207925053 0.977697797 1.434720406 0.559795211 0.16097598 0.144655497 1.365115877 0.021061164 0.057134485 4.09E-06 5.388541546 0.457022609 LGS(ph)PLAVDEALR ddPTM_HeLa_Curcumin_4h_R1 3 LGSPLAVDEALR 12 0 Q7RTP6 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 0 LGS(1)PLAVDEALR;LGS(1)PLAVDEALR;LGS(1)PLAVDEALR ;; 178.22 0.00012142 26049500 6112.7 5172.18 5049.7 5829 5805.1 6204.7 5889.8 9060.4 6542.2 5282.6 TRUE FALSE FALSE 5628.873345 5619.240192 5236.846324 5804.881142 5735.877974 4917.775279 6055.051936 11822.87425 5824.537028 5466.169957 1.029765519 1.028003197 0.958046743 1.061964993 1.049341316 0.899674785 1.107732102 2.162917426 1.065560909 1 12.4163146 -4.263651767 4.269664326 1.010756535 2.248840444 0.980656652 0.048224443 0.016202392 0.680257525 0.005685422 0.060670021 5.45E-05 4.263651767 1.238083909 up ESTESSNT(ph)TIEDEDVKAR ddPTM_HeLa_Curcumin_4h_R1 1 ESTESSNTTIEDEDVKAR 18 1 H0Y9J2;D6R938;Q13557-8;Q13557-12;Q13557;E9PBG7;E9PF82;Q13557-10;Q13557-6;Q13557-11 H0Y9J2 CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 1 0 ES(0.016)T(0.016)ES(0.059)S(0.075)NT(0.712)T(0.122)IEDEDVKAR 69.72 0.011936 4425000 1053.2 1210.8 938.14 1057 1132.4 1781.2 1307.7 1007.3 1330.6 1112.2 TRUE FALSE FALSE 969.8381087 1315.456157 972.9082937 1052.626414 1118.89687 1411.759042 1344.390543 1314.421133 1184.636509 1150.848867 0.842715439 1.143031196 0.845383196 0.91465217 0.972236148 1.226711067 1.168172973 1.142131839 1.029358887 1 10.16848267 -5.343217008 5.002924125 0.935260773 1.17747013 0.542953332 0.088098021 0.111253741 4.870611831 0.012822073 0.029495745 4.54E-06 5.343217008 0.242209357 ESTESSNTT(ph)IEDEDVKAR ddPTM_HeLa_Curcumin_4h_R1 3 ESTESSNTTIEDEDVKAR 18 1 H0Y9J2;D6R938;Q13557-8;Q13557-12;Q13557;E9PBG7;E9PF82;Q13557-10;Q13557-6;Q13557-11 H0Y9J2 CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 1 0 ESTESSNT(0.163)T(0.837)IEDEDVKAR;ESTESSNT(0.002)T(0.998)IEDEDVKAR;ESTESSNT(0.012)T(0.988)IEDEDVKAR ;; 138.04 0.00016783 137001000 4630.45 4069.59 3981.13 3992.81 4297.51 5930.38 4534.94 4985.12 5077.63 3741.24 TRUE FALSE FALSE 4263.944996 4421.347226 4128.67418 3976.28881 4246.265 4700.352339 4662.178211 6505.060139 4520.626693 3871.247812 1.101439434 1.142098734 1.066497001 1.027133628 1.096872432 1.214169841 1.204308905 1.680352294 1.167744074 1 11.91858295 -1 0.815070814 1.056966029 172.3679372 0.88863479 0.061028934 104.4262676 0.320329859 0.009075862 33098.87592 0.1 1 171.3109712 ESTGAQVQVAGDMLPNSTER ddPTM_HeLa_Curcumin_4h_R1 1 ESTGAQVQVAGDMLPNSTER 20 0 Q15365;Q15366;Q15366-2;Q15366-3;Q15366-6;Q15366-5;H3BRU6;F8VZX2;Q15366-8;Q15366-4;P57721;E9PFP8;J3QT27;F8W0G4;P57721-4;P57721-5;P57721-3;P57721-2;Q15366-7;F8VXH9 Q15365;Q15366 PCBP1;PCBP2;PCBP3 Poly(rC)-binding protein 1;Poly(rC)-binding protein 2;Poly(rC)-binding protein 3 0 0 80.371 0.013976 8570700 975.25 846.58 907.64 876.15 730.38 1238.3 802.59 580.54 1173.1 1176.6 FALSE FALSE TRUE 898.0579334 919.7546029 941.2779368 872.5247234 721.6706955 981.4626215 825.1085153 757.5439735 1044.413865 1217.486762 0.737632606 0.755453473 0.773131968 0.716660542 0.592754449 0.806138228 0.677714568 0.622219474 0.857844124 1 10.24969037 -11.49322062 0.213328202 1.573761653 0.652051229 0.578347896 0.072667158 6.440239301 0.172598949 1.695502915 0.055682349 3.21E-12 11.49322062 -0.921710424 ESTLHLVLR ddPTM_HeLa_Curcumin_4h_R1 1 ESTLHLVLR 9 0 P62979;A0A2R8Y422;J3QTR3;J3QS39;F5H388;Q96C32;Q5PY61;J3QKN0;F5GXK7;F5H747;F5H265;B4DV12;M0R2S1;F5H2Z3;F5GYU3;F5H6Q2;M0R1M6;P62987;P0CG47;P0CG48 P62979 RPS27A;UBB;UBC;UBA52 Ubiquitin-40S ribosomal protein S27a;Ubiquitin;40S ribosomal protein S27a;Ubiquitin-60S ribosomal protein L40;Ubiquitin;60S ribosomal protein L40;Polyubiquitin-B;Ubiquitin;Polyubiquitin-C;Ubiquitin 0 0 90.601 0.005912 1992500 1394.4 1095.8 1273.7 1018.6 1981.6 2310.4 1480 1856.5 1359.8 1023.8 FALSE FALSE TRUE 1284.031769 1190.516069 1320.904442 1014.385303 1957.970714 1831.196996 1521.524817 2422.538304 1210.633342 1059.376974 1.212063128 1.123788886 1.246869127 0.957530065 1.848228499 1.728560316 1.436244939 2.28675756 1.142778607 1 10.04900034 -1 0.297655754 1.044102071 10.30079877 0.689275428 0.226667029 19.60058658 0.250733255 0.083095666 97.68865457 0.1 1 9.256696701 ESTNSMETR ddPTM_HeLa_Curcumin_4h_R1 1 ESTNSMETR 9 0 P61758-2;P61758 P61758-2 VBP1 Prefoldin subunit 3 0 0 110.41 0.0034885 708420 672.56 406.88 464.49 468.38 539.8 635.29 721.87 460.22 761.89 583.96 FALSE FALSE TRUE 619.3261663 442.0488942 481.704408 466.4419677 533.3632376 503.5236928 742.1237294 600.5389594 678.3125732 604.2525665 1.02494586 0.731563122 0.797190504 0.771932125 0.882682618 0.833300048 1.228168105 0.993854214 1.122564654 1 9.239007886 -4.763420934 24.99999539 0.940757129 1.111011145 0.244598624 0.133752788 61.72911245 778851.2743 0.020018671 0.064847896 1.72E-05 4.763420934 0.170254016 ESTQLS(ph)PADLTEGKPTDPSK ddPTM_HeLa_Curcumin_4h_R1 1 ESTQLSPADLTEGKPTDPSK 20 1 Q08J23-2;Q08J23;Q08J23-3 Q08J23-2 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 0 ES(0.113)T(0.091)QLS(0.641)PADLT(0.123)EGKPT(0.029)DPS(0.003)K 69.975 0.00285 103630000 2324.7 1947.6 2239.5 2067.8 2721.2 2471.9 2090 2267.4 1776.7 1949.6 TRUE FALSE FALSE 2140.697542 2115.941866 2322.49784 2059.243991 2688.751467 1959.200076 2148.639775 2958.719822 1581.800455 2017.348455 1.061144165 1.048872772 1.151262606 1.020767625 1.332814597 0.971175838 1.065081132 1.46663796 0.784098776 1 10.97824459 -4.262112134 6.827875947 1.056356495 1.473281156 0.478093902 0.130897735 0.055990422 18.33496978 0.013263109 0.10779776 5.47E-05 4.262112134 0.416924661 ESTQLS(ph)PADLTEGKPTDPSKLES(ph)PSFTGTGDTEIAHATEDLENNGSK ddPTM_HeLa_Curcumin_4h_R1 1 ESTQLSPADLTEGKPTDPSKLESPSFTGTGDTEIAHATEDLENNGSK 47 2 Q08J23-2;Q08J23;Q08J23-3 Q08J23-2 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 2 0 ES(0.011)T(0.024)QLS(0.525)PADLT(0.124)EGKPT(0.124)DPS(0.231)KLES(0.24)PS(0.24)FT(0.24)GT(0.118)GDT(0.118)EIAHAT(0.008)EDLENNGSK 43.333 0.0050929 8103100 1011.6 1007.9 1061.2 920.54 1611.8 2088.4 1485.7 953.49 1496.7 1052.8 TRUE FALSE FALSE 931.5307926 1095.018385 1100.529006 916.7310494 1592.580338 1655.242299 1527.384743 1244.204712 1332.515755 1089.384722 0.855098088 1.005171418 1.010229888 0.841512673 1.46190809 1.519428597 1.402061836 1.14211691 1.223181974 1 10.08929782 -5.759429116 24.9999984 0.937039757 1.392716966 0.643218568 0.139789508 17.2621935 214670.282 0.016316711 0.031375051 1.74E-06 5.759429116 0.455677209 ESTQLSPADLT(ph)EGKPTDPSK ddPTM_HeLa_Curcumin_4h_R1 1 ESTQLSPADLTEGKPTDPSK 20 1 Q08J23-2;Q08J23;Q08J23-3 Q08J23-2 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 0 ES(0.017)T(0.037)QLS(0.224)PADLT(0.689)EGKPT(0.032)DPS(0.001)K 77.554 0.0027223 53202000 4678.3 3752.6 4432.7 3968.6 5475.6 5539.4 4660.4 4330.4 3833.8 3522.2 TRUE FALSE FALSE 4308.007618 4076.958023 4596.979761 3952.178985 5410.307046 4390.465998 4791.158281 5650.719025 3413.241732 3644.596188 1.182026045 1.11863093 1.261313881 1.084394205 1.484473661 1.204650878 1.314592354 1.550437616 0.936521237 1 11.83154326 -1 0.13020222 0.933990982 2.658881128 0.664247952 0.108170341 37.25017236 0.32698083 0.334783054 11.84579549 0.1 1 1.724890146 ESVAS(ph)GDDRAEEDMDEAIEK ddPTM_HeLa_Curcumin_4h_R1 4 ESVASGDDRAEEDMDEAIEK 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 ES(0.033)VAS(0.967)GDDRAEEDMDEAIEK;ES(0.018)VAS(0.982)GDDRAEEDMDEAIEK;ES(0.068)VAS(0.932)GDDRAEEDMDEAIEK;ES(0.093)VAS(0.907)GDDRAEEDMDEAIEK ;;; 70.316 0.0027872 61475200 3219.14 2723.12 3306.79 2994.2 3662.33 3679.39 3049.92 2612.48 2799.41 2723.51 TRUE FALSE FALSE 2964.341672 2958.494359 3429.342546 2981.810794 3618.659107 2916.243039 3135.492547 3409.013126 2492.321727 2818.15177 1.051874389 1.049799514 1.216876459 1.058073176 1.284054019 1.03480695 1.112605992 1.209662717 0.884381655 1 11.46053359 -6.910784105 6.720466943 1.025829202 1.146963769 0.439579069 0.084064396 0.155787781 9.868229029 0.010759085 0.014174855 1.23E-07 6.910784105 0.121134567 ESVASMGADS(ph)GDDFASDGSSSR ddPTM_HeLa_Curcumin_4h_R1 1 ESVASMGADSGDDFASDGSSSR 22 0 Q5T165;Q92805 Q5T165 GOLGA1 Golgin subfamily A member 1 1 0 ESVASMGADS(0.995)GDDFAS(0.001)DGS(0.001)S(0.002)S(0.001)R 96.55 0.0005579 0 1146 914.55 942.38 1005.3 1042.8 1400.8 906.69 689.01 1054.8 769.48 TRUE FALSE FALSE 1055.292891 993.5996268 977.3054318 1001.140335 1030.365291 1110.25829 932.1292812 899.0859772 939.091079 796.2193727 1.325379571 1.247896825 1.22743237 1.257367466 1.294072119 1.394412555 1.170694049 1.129193798 1.179437616 1 9.637022164 -9.35712168 0.980496855 0.993453183 1.262389596 0.282708228 0.088784936 0.294254696 0.486463423 0.057539169 0.013596282 4.39E-10 9.35712168 0.268936414 LLEENETEAVTVPTPS(ph)PTPVR ddPTM_HeLa_Curcumin_4h_R1 2 LLEENETEAVTVPTPSPTPVR 21 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 0 LLEENETEAVTVPT(0.016)PS(0.737)PT(0.247)PVR;LLEENETEAVTVPT(0.081)PS(0.684)PT(0.235)PVR ; 152.03 1.39E-06 57733600 3763 3329.92 3053.46 3744.4 3526.9 3669.1 2138.36 1138.27 4010.4 3378.93 TRUE FALSE FALSE 3465.154579 3617.743447 3166.623914 3728.906665 3484.844021 2908.087301 2198.356626 1485.323283 3570.469154 3496.347566 0.991078408 1.03472077 0.90569483 1.066514869 0.996709839 0.831750061 0.628758035 0.424821404 1.021199719 1 11.77163289 -4.668996851 1.498864116 0.99824797 0.386755929 0.955386637 0.041781639 0.074184194 0.250214389 0.005608244 0.053555082 2.14E-05 4.668996851 -0.61149204 down ESVPEFPLS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 6 ESVPEFPLSPPK 12 0 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 1 0 ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK;ESVPEFPLS(1)PPK ;;;;; 197.38 1.84E-06 1278811000 39975.8 43711.1 42636.7 39355.4 48437.2 49714.4 39967.7 29335.65 36722 32719 TRUE FALSE FALSE 36811.67325 47489.29271 44216.85361 39192.55778 47859.61803 39403.07304 41089.08609 38279.95464 32693.68847 33855.98281 1.087301865 1.402685397 1.306027766 1.157625758 1.413623651 1.163843722 1.213643282 1.130670312 0.965669455 1 15.04712318 -7.450435199 6.147854349 1.037810602 1.254811661 0.56739226 0.095572469 0.129939181 8.505810462 0.016068601 0.018172067 3.54E-08 7.450435199 0.21700106 ESVPEFPLS(ph)PPKKK ddPTM_HeLa_Curcumin_4h_R1 1 ESVPEFPLSPPKKK 14 2 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 1 0 ESVPEFPLS(1)PPKKK 82.259 0.012303 403100000 1960.1 1510.6 1603.2 1611.5 1571.8 1970.8 1332.5 1116.7 2010.7 1580.2 TRUE FALSE FALSE 1804.956017 1641.169533 1662.616002 1604.83204 1553.057312 1562.033865 1369.886364 1457.176689 1790.131241 1635.111832 1.10387313 1.003704762 1.016820972 0.981481516 0.949817181 0.955307052 0.837793683 0.89117861 1.094806609 1 10.6751736 -5.480867846 0.791857568 1.046816914 0.856850729 0.767041583 0.037497448 0.348574849 0.359887279 0.007981701 0.040662253 3.30E-06 5.480867846 -0.189966185 ESVPEFPLSPPK ddPTM_HeLa_Curcumin_4h_R1 2 ESVPEFPLSPPK 12 0 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 0 0 ; ; 151.22 4.54E-17 748630 1947.94 1401.67 1553.25 1297.49 1647.16 2407.2 1688.57 1570.19 1785.32 1392.4 FALSE FALSE TRUE 1793.758494 1522.824109 1610.814811 1292.12133 1627.518693 1907.919585 1735.94673 2048.933703 1589.474863 1440.785796 1.244986242 1.056939979 1.118011307 0.896817093 1.129604898 1.324221539 1.204861079 1.422094601 1.103199981 1 10.49264015 -5.31071038 5.297104798 1.09711609 1.306221759 0.544605515 0.099021139 0.158483407 10.44975959 0.017078739 0.039556229 4.89E-06 5.31071038 0.209105669 ESVS(ph)PEDSEK ddPTM_HeLa_Curcumin_4h_R1 1 ESVSPEDSEK 10 0 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 0 ES(0.002)VS(0.975)PEDS(0.022)EK 151.13 0.00071048 179160000 6276.6 4248.3 5559.2 7324.6 7186.5 7526.8 6766.9 4396.2 6374.2 5342.9 TRUE FALSE FALSE 5779.800487 4615.504122 5765.228842 7294.292746 7100.805681 5965.656835 6956.761002 5736.581142 5674.966207 5528.565377 1.045443093 0.834846621 1.042807392 1.319382561 1.284384862 1.079060557 1.258330241 1.037625632 1.026480799 1 12.43268944 -6.437827826 7.714850575 1.004859789 1.196889413 0.523281898 0.098366298 0.192889346 15.68354686 0.014693182 0.022449917 3.65E-07 6.437827826 0.192029625 ESVSPEDS(ph)EK ddPTM_HeLa_Curcumin_4h_R1 1 ESVSPEDSEK 10 0 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 0 ES(0.001)VS(0.42)PEDS(0.579)EK 118.23 0.0048725 208100000 1995.2 1325.1 1976.3 2062.4 2208 2365.3 2117.5 1290.6 2040.4 1650.8 TRUE FALSE FALSE 1837.277815 1439.635739 2049.543417 2053.866335 2181.671042 1874.710118 2176.911351 1684.097999 1816.573225 1708.165177 1.075585569 0.842796563 1.199850836 1.202381575 1.277201451 1.097499318 1.274415016 0.985910509 1.063464616 1 10.73823177 -6.665024395 21.74633244 1.022122199 1.180157488 0.417529341 0.100482673 4.384025403 982.8964766 0.01465223 0.020721392 2.16E-07 6.665024395 0.158035289 ESVSTEDLS(ph)PPSPPLPK ddPTM_HeLa_Curcumin_4h_R1 1 ESVSTEDLSPPSPPLPK 17 0 Q13127-4;Q13127 Q13127-4 REST RE1-silencing transcription factor 1 0 ESVSTEDLS(0.846)PPS(0.154)PPLPK 148.18 0.00024654 24991000 4534 3361 4364.9 4550.2 3859.1 5418.3 4250.6 2878.6 5008.9 4152.2 TRUE FALSE FALSE 4175.129116 3651.509864 4526.667034 4531.372478 3813.082753 4294.483503 4369.860396 3756.271889 4459.436202 4296.488641 0.971753789 0.84988235 1.053573607 1.05466879 0.887488149 0.999533308 1.017077144 0.874265523 1.037925752 1 12.06894237 -5.302090127 0.005063063 1.929363996 3.71E-05 0.070682719 0.070146098 47089.856 55.54969053 10330.22164 10840.74776 4.99E-06 5.302090127 -1.929326874 ESVSTEDLSPPS(ph)PPLPK ddPTM_HeLa_Curcumin_4h_R1 1 ESVSTEDLSPPSPPLPK 17 0 Q13127-4;Q13127 Q13127-4 REST RE1-silencing transcription factor 1 0 ESVSTEDLS(0.019)PPS(0.981)PPLPK 174.4 2.85E-05 10901000 3986.3 3381.4 4156.5 3985.6 3237 4297.8 3198.2 1999.7 4283.9 3132.7 TRUE FALSE FALSE 3670.780149 3673.673149 4310.543546 3969.108643 3198.400889 3406.387834 3287.932884 2609.399325 3813.966888 3241.561092 1.132411219 1.133303691 1.329773965 1.224443572 0.986685365 1.050847952 1.014305389 0.804982307 1.176583374 1 11.66247305 -3.792717998 1.094201762 1.096791072 0.316346161 0.479633819 0.100420269 3.44734544 1.634842928 0.017207434 3.982906209 0.000161169 3.792717998 -0.780444911 AAS(ph)DSNPAGPLR ddPTM_HeLa_Curcumin_4h_R1 1 AASDSNPAGPLR 12 0 Q9BUU2-2;Q9BUU2 Q9BUU2-2 METTL22 Methyltransferase-like protein 22 1 0 AAS(0.968)DS(0.032)NPAGPLR 106.55 0.0066054 24897000 1735.7 1369.5 1310.6 1216.5 1611.5 1719.3 1686.2 2847.4 1845.4 1542.3 TRUE FALSE FALSE 1598.317513 1487.873478 1359.171989 1211.466445 1592.283915 1362.697799 1733.510234 3715.559152 1642.964237 1595.89481 1.001518085 0.932313 0.851667654 0.759114221 0.997737385 0.853876954 1.086230886 2.328198029 1.029494066 1 10.64014985 -4.263104893 4.052608601 0.959832751 2.445345507 0.959083424 0.086005218 0.033689226 1.17136135 0.012875241 0.145678495 5.46E-05 4.263104893 1.485512756 up RLAAQLGAPT(ph)SPIPDSAIVNTR ddPTM_HeLa_Curcumin_4h_R1 1 RLAAQLGAPTSPIPDSAIVNTR 22 1 Q9H8Y5;B8ZZS4 Q9H8Y5 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 0 RLAAQLGAPT(0.935)S(0.065)PIPDSAIVNTR 80.172 0.00057795 0 828.64 535.71 462.77 655.96 542.57 694.99 637.7 918.76 775.7 547.63 TRUE FALSE FALSE 763.0522696 582.0143853 479.9206633 653.2458113 536.1002071 550.8412398 655.5921457 1198.885695 690.6076507 566.6601017 1.346578429 1.027096108 0.846928629 1.152800081 0.946070149 0.972084038 1.156940719 2.115705148 1.218733503 1 9.146339816 -4.262938894 5.245076439 1.106593683 2.157700782 0.8280048 0.141899753 0.058250101 5.516765889 0.024207648 0.219837247 5.46E-05 4.262938894 1.051107099 up ESYS(ph)IYVYK ddPTM_HeLa_Curcumin_4h_R1 1 ESYSIYVYK 9 0 P33778;Q16778;P06899;Q8N257 P33778;Q16778;Q8N257 HIST1H2BB;HIST2H2BE;HIST1H2BJ;HIST3H2BB Histone H2B type 1-B;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 3-B 1 0 ES(0.197)YS(0.802)IYVY(0.001)K 123.79 0.002102 0 2499.9 1822.5 2271.5 2224.1 1812 2562.6 2101.6 1498 2431.4 1476.3 TRUE FALSE FALSE 2302.030277 1980.028779 2355.683788 2214.897264 1790.393083 2031.087874 2160.56524 1954.733304 2164.681503 1527.601315 1.506957512 1.296168548 1.542080231 1.449918406 1.172029027 1.329592907 1.414351519 1.279609598 1.417046111 1 10.57705235 -9.412412461 1.093395139 0.99606899 1.383834127 0 0.164885463 0.266060404 0.559667714 0.080107992 0.019463253 3.87E-10 9.412412461 0.387765137 ESYS(ph)VYVYK ddPTM_HeLa_Curcumin_4h_R1 2 ESYSVYVYK 9 0 P58876;P62807;P57053;O60814;Q5QNW6;Q5QNW6-2;Q93079;U3KQK0;Q99877;Q99879;Q99880 P58876;P62807;Q5QNW6;Q93079;U3KQK0;Q99879;Q99880 HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BF;HIST1H2BH;HIST1H2BN;HIST1H2BM;HIST1H2BL Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-F;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-M;Histone H2B type 1-L 1 0 ES(0.005)YS(0.995)VYVYK;ESYS(0.999)VYVYK ; 117.67 0.0068379 20331500 3484.7 2437 2921 4034.7 2876.7 3584.9 3123.4 2738.3 3175.4 2822.3 TRUE FALSE FALSE 3208.882318 2647.643421 3029.25483 4018.00548 2842.397231 2841.35133 3211.034198 3573.195064 2827.066564 2920.374715 1.098791296 0.906610856 1.037282926 1.375852715 0.973298809 0.972940669 1.099528147 1.223539927 0.968049254 1 11.51193778 -13.52286151 0.014301597 2.45E-07 1.934025844 0.121090933 0.125939194 11498.06952 13.2839059 1098.47192 732.8327961 3.00E-14 13.52286151 1.934025599 ESYSIYVYK ddPTM_HeLa_Curcumin_4h_R1 1 ESYSIYVYK 9 0 P33778;Q16778;P06899;Q8N257 P33778;Q16778;Q8N257 HIST1H2BB;HIST2H2BE;HIST1H2BJ;HIST3H2BB Histone H2B type 1-B;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 3-B 0 0 167.33 0.00608 33350000 1543.2 1262.8 1408.4 1356.5 1558.2 1957.2 1822.9 1781.3 1648 1481 FALSE FALSE TRUE 1421.054092 1371.950805 1460.596543 1350.887162 1539.619483 1551.254658 1874.045668 2324.41017 1467.218523 1532.46464 0.927299759 0.895257724 0.953102933 0.881512778 1.004668847 1.012261306 1.222896515 1.516778991 0.957424064 1 10.58163807 -4.344777585 1.403464038 0.953393099 1.698284815 0.959578106 0.036932535 0.167651362 0.325859957 0.00639895 0.167444917 4.52E-05 4.344777585 0.744891715 ESYSVYVYK ddPTM_HeLa_Curcumin_4h_R1 3 ESYSVYVYK 9 0 P58876;P62807;P57053;O60814;Q5QNW6;Q5QNW6-2;Q93079;U3KQK0;Q99877;Q99879;Q99880 P58876;P62807;Q5QNW6;Q93079;U3KQK0;Q99879;Q99880 HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BF;HIST1H2BH;HIST1H2BN;HIST1H2BM;HIST1H2BL Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-F;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-M;Histone H2B type 1-L 0 0 ;; ;; 170.24 1.93E-07 214430000 9410.9 7189.6 9986.2 8700.5 7573.6 10626.3 9003.9 7899.1 6395.5 5156.88 FALSE FALSE TRUE 8666.017335 7811.036988 10356.29736 8664.499636 7483.289766 8422.285597 9256.525201 10307.49923 5693.929651 5336.081196 1.624041505 1.463815242 1.940805804 1.623757083 1.402394284 1.578365337 1.734704713 1.931660866 1.067062033 1 12.3815649 -9.384199018 0.441531333 0.786868128 1.69212106 0.706995888 0.163055963 0.932715547 0.224432992 0.389460734 0.050366897 4.13E-10 9.384199018 0.905252932 ESYTEEIVS(ph)EAESHVS(ph)GISR ddPTM_HeLa_Curcumin_4h_R1 2 ESYTEEIVSEAESHVSGISR 20 0 E9PRB3;J3KP30;Q5QJE6 E9PRB3 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 2 0 ES(0.002)YT(0.033)EEIVS(0.965)EAES(0.089)HVS(0.868)GIS(0.044)R;ES(0.012)YT(0.276)EEIVS(0.712)EAESHVS(0.993)GIS(0.006)R ; 134.69 0.00022243 8658600 2072.1 2020.26 1998.8 2327.1 2383.61 2385.3 2363.5 1264.93 2195.3 1945.78 TRUE FALSE FALSE 1908.091099 2194.882272 2072.877286 2317.471077 2355.187008 1890.561892 2429.813449 1650.601334 1954.481082 2013.39571 0.947698005 1.090139539 1.029542914 1.151026132 1.16975863 0.938991716 1.206823595 0.8198097 0.970738674 1 10.97541503 -7.260123569 24.78888195 0.975301836 1.065939218 0.111465051 0.108565746 148.6755348 2800931.825 0.016511388 0.019632395 5.49E-08 7.260123569 0.090637383 ESYTEEIVS(ph)EAESHVSGISR ddPTM_HeLa_Curcumin_4h_R1 4 ESYTEEIVSEAESHVSGISR 20 0 E9PRB3;J3KP30;Q5QJE6 E9PRB3 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 0 ESYTEEIVS(1)EAESHVSGISR;ESYTEEIVS(1)EAESHVSGISR;ESYTEEIVS(1)EAESHVSGISR;ESYTEEIVS(0.998)EAES(0.002)HVSGISR ;;; 198.45 3.36E-11 15720900 5455.34 4648.57 4252.57 4648.44 7053.77 12936.2 6896.19 4509.1 6809.63 4824.81 TRUE FALSE FALSE 5023.544083 5050.371677 4410.173985 4629.205987 6969.6584 10253.0863 7089.678531 5883.903833 6062.630626 4992.471788 1.00622383 1.011597439 0.883364829 0.927237285 1.396033607 2.053709412 1.42007383 1.178555249 1.214354509 1 12.28553856 -5.649181468 4.71222925 0.989550652 1.56428673 0.564375268 0.21922347 0.101651092 3.763961406 0.029449145 0.060003825 2.24E-06 5.649181468 0.574736078 ESYTEEIVSEAESHVS(ph)GISR ddPTM_HeLa_Curcumin_4h_R1 1 ESYTEEIVSEAESHVSGISR 20 0 E9PRB3;J3KP30;Q5QJE6 E9PRB3 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 0 ESYTEEIVSEAES(0.001)HVS(0.952)GIS(0.047)R 195.31 8.00E-11 4375000 2288.8 1802.4 1390.4 1591.4 2010.5 2025.6 1715.1 847.43 1740.8 1612.5 TRUE FALSE FALSE 2107.639065 1958.191425 1441.929447 1584.815208 1986.526101 1605.467727 1763.22109 1105.807506 1549.838595 1668.534255 1.263167992 1.173599774 0.864189298 0.949824796 1.190581551 0.962202437 1.056748511 0.662741866 0.928862318 1 10.70436559 -6.774062302 24.99489209 1.131445588 0.964464661 0.148140353 0.154402764 267.9796396 530630.8391 0.025172742 0.033206898 1.68E-07 6.774062302 -0.166980927 ET(ph)RSSSESLIFSGNQGR ddPTM_HeLa_Curcumin_4h_R1 1 ETRSSSESLIFSGNQGR 17 1 Q8IZW8 Q8IZW8 TNS4 Tensin-4 1 0 ET(0.693)RS(0.077)S(0.211)S(0.018)ESLIFSGNQGR 84.859 0.0056662 10983000 1889.8 1788.6 1750.6 2181.1 1635.4 1766.1 1760.2 1039.1 1794.9 1964 TRUE FALSE FALSE 1740.220336 1943.198614 1815.478776 2172.075186 1615.898923 1399.790952 1809.586475 1355.916807 1598.003961 2032.248854 0.856302776 0.95618143 0.893334875 1.068803745 0.795128471 0.688789146 0.890435476 0.667200183 0.786322973 1 10.98886136 -5.586093442 9.593428207 0.937786034 0.759479973 0.444979307 0.091432119 0.211032642 30.31775867 0.01177784 0.023581346 2.59E-06 5.586093442 -0.178306061 ET(ph)SHGSPTVTK ddPTM_HeLa_Curcumin_4h_R1 1 ETSHGSPTVTK 11 0 Q8NI08-2;Q8NI08;Q8NI08-7 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 0 ET(0.993)S(0.005)HGS(0.002)PTVTK 184.36 0.00028942 7124300 2437 3059.8 2276.6 2038.8 2028.5 3535 2028.9 797.94 2542.5 2277.2 TRUE FALSE FALSE 2244.108878 3324.275478 2360.972799 2030.363986 2004.311462 2801.801152 2085.825473 1041.228233 2263.594111 2356.332531 0.952373593 1.41078368 1.001969276 0.861662757 0.850606371 1.189051679 0.885199965 0.441885099 0.960642898 1 11.20232743 -4.300542228 3.524589655 1.004565135 0.396615424 0.549646921 0.158033524 0.148624085 3.206464401 0.021475722 0.223751933 5.01E-05 4.300542228 -0.607949711 ET(ph)SPQVKGEEMPAGKDQEASR ddPTM_HeLa_Curcumin_4h_R1 1 ETSPQVKGEEMPAGKDQEASR 21 2 Q9GZR2;A0A0C4DG22 Q9GZR2 REXO4 RNA exonuclease 4 1 0 ET(0.516)S(0.483)PQVKGEEMPAGKDQEASR 47.807 0.017671 26196000 4751.9 3295.7 4018.9 4701.5 3226.1 5582.1 3421 2606.4 5737.3 4439.6 TRUE FALSE FALSE 4375.782101 3580.565623 4167.843969 4682.046439 3187.630865 4424.309537 3516.984053 3401.079362 5107.932544 4593.87577 0.952525127 0.779421517 0.907260923 1.01919309 0.693887041 0.963088633 0.76558101 0.740350748 1.111900452 1 12.16549613 -1 0.135128454 1.0491911 0.047277727 0.442427116 0.099071172 54.66210784 0.493002912 0.264574987 10.54849616 0.1 1 -1.001913373 ET(ph)T(ph)EVDLLT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 ETTEVDLLTK 10 0 C9JHK9;C9JZV3;Q9UG63;Q9UG63-2 C9JHK9 ABCF2 ATP-binding cassette sub-family F member 2 3 0 ET(1)T(1)EVDLLT(1)K 64.297 0.0080613 0 5744.8 9000.7 8390.9 7054.5 5059.6 7676.2 7461.5 5560.9 8318.3 12135 TRUE FALSE FALSE 5290.093018 9778.680402 8701.874135 7025.310348 4999.267575 6084.069591 7670.849608 7256.392811 7405.803301 12556.69035 0.421296765 0.778762567 0.693006986 0.559487425 0.39813577 0.484528122 0.61089741 0.57789056 0.589789435 1 13.61616863 -9.43106707 1.001969831 1.017048017 0.556452378 0.042855934 0.165937761 0.288314851 0.485782743 0.100457512 0.021708786 3.71E-10 9.43106707 -0.460595639 ET(ph)VNSPAIYK ddPTM_HeLa_Curcumin_4h_R1 2 ETVNSPAIYK 10 0 Q9Y3A2 Q9Y3A2 UTP11L Probable U3 small nucleolar RNA-associated protein 11 1 0 ET(0.919)VNS(0.08)PAIY(0.001)K;ET(0.987)VNS(0.013)PAIYK ; 160.22 0.0017785 72712000 6275.3 5459.8 5636.4 5983.9 5994.9 9229.4 6961.8 3446.9 7157.5 5716.8 TRUE FALSE FALSE 5778.603383 5931.720784 5845.289942 5959.140207 5923.414733 7315.118403 7157.129371 4497.843942 6372.340157 5915.458374 0.976864854 1.002749138 0.988138124 1.007384353 1.001345011 1.236610579 1.209902753 0.760354255 1.077235229 1 12.53027425 -5.484665435 24.92142286 0.991559944 1.089038438 0.031480997 0.12346407 829.110195 540716.835 0.015849305 0.035432739 3.28E-06 5.484665435 0.097478494 ETAPTSAYSS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 2 ETAPTSAYSSPAR 13 0 A0A6I8PRZ9;A0A6I8PIX2;A0A6I8PIU5;A0A6I8PIW1;O43301 A0A6I8PRZ9 HSPA12A Heat shock 70 kDa protein 12A 1 0 ETAPTS(0.001)AYS(0.23)S(0.768)PAR;ETAPTSAYS(0.003)S(0.997)PAR ; 169.09 0.00019141 122555000 5467.7 5424.6 5430.6 5347.3 5720 8557.6 6433.7 2719.3 5537.5 4145.4 TRUE FALSE FALSE 5034.925776 5893.478252 5631.862813 5325.174289 5651.792736 6782.657296 6614.212307 3548.402052 4930.050104 4289.452341 1.173792217 1.373946552 1.312956146 1.241457852 1.317602408 1.581240857 1.541971277 0.82723895 1.149342553 1 12.06657775 -7.882307354 0.73097524 1.02360383 1.339140242 0.164713955 0.199411799 0.519658144 0.613680467 0.063873145 0.049552935 1.31E-08 7.882307354 0.315536411 ETAVPGPLGIEDIS(ph)PNLSPDDKSFSR ddPTM_HeLa_Curcumin_4h_R1 2 ETAVPGPLGIEDISPNLSPDDKSFSR 26 1 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 ETAVPGPLGIEDIS(1)PNLSPDDKSFSR;ETAVPGPLGIEDIS(0.997)PNLS(0.002)PDDKSFSR ; 122.82 1.05E-08 49902000 7835.1 6072.7 5606.5 6513.4 5006 6356.4 3864 5387.9 8712.2 7684.8 TRUE FALSE FALSE 7214.943567 6597.597129 5814.281822 6486.449277 4946.30672 5038.010989 3972.413441 7030.645907 7756.493457 7951.846228 0.907329362 0.829693752 0.731186401 0.815716136 0.622032491 0.633564941 0.499558634 0.884152649 0.97543303 1 12.95707414 -6.882384169 0.658523121 0.979830344 0.645822895 0.606334781 0.097977832 0.28756519 0.259064447 0.02344683 0.036778551 1.31E-07 6.882384169 -0.33400745 ETAVPGPLGIEDISPNLS(ph)PDDK ddPTM_HeLa_Curcumin_4h_R1 1 ETAVPGPLGIEDISPNLSPDDK 22 0 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 ETAVPGPLGIEDIS(0.007)PNLS(0.993)PDDK 77.169 0.00055025 5090900 3944.4 3740.1 3721.4 4179.9 5089.4 4064.4 3427 2132.3 3925.9 2992.4 TRUE FALSE FALSE 3632.196578 4063.377578 3859.318358 4162.604681 5028.712229 3221.397625 3523.152397 2782.428454 3495.238592 3096.385677 1.17304398 1.312296982 1.24639459 1.344343087 1.624058742 1.040373507 1.137827378 0.898605259 1.128812414 1 11.59636947 -8.419016768 0.892962687 1.020539601 1.235294806 0.09262914 0.185813887 0.665998784 1.104108347 0.070009248 0.040229287 3.81E-09 8.419016768 0.214755205 ETAVPGPLGIEDISPNLS(ph)PDDKSFSR ddPTM_HeLa_Curcumin_4h_R1 2 ETAVPGPLGIEDISPNLSPDDKSFSR 26 1 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 ETAVPGPLGIEDIS(0.078)PNLS(0.919)PDDKS(0.003)FSR;ETAVPGPLGIEDISPNLS(0.996)PDDKS(0.003)FS(0.001)R ; 106.18 9.29E-08 348310000 13073.7 10359.1 10249.8 10756.9 10082.3 13787.9 9011.3 5890.2 13849.5 10054.2 TRUE FALSE FALSE 12038.90285 11254.49444 10629.6666 10712.3908 9962.075157 10928.13412 9264.132825 7686.094865 12330.2445 10403.5827 1.157188172 1.081790261 1.021731351 1.029682861 0.957561971 1.050420267 0.890475242 0.738793076 1.185192145 1 13.34479282 -3.467671821 0.670418423 1.070478891 3.55E-11 0.745423639 0.061865587 3.134069667 0.457122569 0.011453669 3.284805601 0.000340666 3.467671821 -1.070478891 ETCSTLAES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 ETCSTLAESPR 11 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 0 ETCSTLAES(1)PR;ETCSTLAES(1)PR;ETCSTLAES(1)PR ;; 199.12 6.50E-06 177270000 6812.4 4965.1 5948.2 6217.2 5722.7 6711.3 5323.6 2252.8 6175 5201.2 TRUE FALSE FALSE 6273.191352 5394.26112 6168.645525 6191.474874 5654.46054 5319.300728 5472.965888 2939.668349 5497.617949 5381.941313 1.165600104 1.002289101 1.146174803 1.150416646 1.05063586 0.988360968 1.016912963 0.546209663 1.021493478 1 12.39391094 -3.990159439 1.647895002 1.079765213 2.90E-15 0.849945754 0.064821204 0.673333649 0.988344515 0.010742378 1.429481134 0.000102292 3.990159439 -1.079765213 ETCSTLAES(ph)PRNGLQEK ddPTM_HeLa_Curcumin_4h_R1 1 ETCSTLAESPRNGLQEK 17 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 0 ETCS(0.002)T(0.003)LAES(0.994)PRNGLQEK 69.986 0.0085658 28294000 1535.3 1316.9 1139.1 1561.4 1044.2 1948.9 1227.8 665.74 2037.7 1992.8 TRUE FALSE FALSE 1413.779385 1430.726968 1181.316048 1554.939341 1031.748597 1544.676171 1262.248764 868.7210613 1814.169408 2062.049652 0.685618498 0.693837303 0.572884386 0.754074636 0.500350996 0.749097467 0.61213306 0.421290079 0.879789391 1 11.00986336 -13.52287875 0.15010936 2.44416536 0.495910247 0.635770087 0.098727223 23.71160354 0.24258515 10.00651154 0.199792766 3.00E-14 13.52287875 -1.948255113 ETDLQELFRPFGSISR ddPTM_HeLa_Curcumin_4h_R1 2 ETDLQELFRPFGSISR 16 1 K7ENA8;O75821;K7EP16 K7ENA8 EIF3G Eukaryotic translation initiation factor 3 subunit G 0 0 ; ; 106.76 0.0016152 37036000 2019.75 1401.21 1887.57 1876.34 2147.2 2258.89 1969.31 1801.53 1765.08 1715.05 FALSE FALSE TRUE 1859.884656 1522.324349 1957.525005 1868.576202 2121.596042 1790.370751 2024.563538 2350.808204 1571.45514 1774.64786 1.048030259 0.857817702 1.103049821 1.052927876 1.19550255 1.008859725 1.140825504 1.324661786 0.885502513 1 10.79331707 -1 0.522724173 1.017088406 11.74284827 0.544694453 0.089134937 57.1835666 0.516720231 0.01447501 684.4405191 0.1 1 10.72575987 SDLNGLPS(ph)PVEER ddPTM_HeLa_Curcumin_4h_R1 2 SDLNGLPSPVEER 13 0 E7EWN3;Q9C0A6 E7EWN3 SETD5 SET domain-containing protein 5 1 0 SDLNGLPS(1)PVEER;S(0.003)DLNGLPS(0.997)PVEER ; 99.392 0.0073533 27260400 3894.7 3064.8 3250.8 4040.6 3459.2 3935.2 2291.7 1332.78 3613.1 3471.2 TRUE FALSE FALSE 3586.430385 3329.707656 3371.277508 4023.881068 3417.951299 3118.995161 2355.998934 1739.138487 3216.75197 3591.823942 0.99849838 0.927024183 0.938597649 1.12028906 0.951592103 0.8683597 0.655933858 0.48419369 0.895576181 1 11.81050092 -4.667589247 1.523005793 0.996508507 0.447930195 0.883628199 0.059482206 0.104061736 0.365457565 0.007228916 0.06803673 2.15E-05 4.667589247 -0.548578312 down ETDSPSTPGK(ac)DQR ddPTM_HeLa_Curcumin_4h_R1 1 ETDSPSTPGKDQR 13 1 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 0 1 ETDSPSTPGK(1)DQR 137.89 0.00073009 613750 208.14 193.54 154.49 136.49 230.97 260.72 188.45 134.1 70.889 116.15 FALSE TRUE FALSE 191.6654994 210.2687352 160.2155353 135.9252405 228.2158336 206.6437331 193.7373998 174.9864727 63.11265406 120.1862039 1.594737942 1.749524725 1.333060952 1.130955436 1.898852167 1.719363175 1.611977029 1.455961392 0.52512395 1 6.909127489 -9.244401357 0.689893505 0.942110597 1.571048421 0.569923054 0.259124027 0.617289231 0.454837038 0.230958401 0.045660504 5.70E-10 9.244401357 0.628937824 ETDVS(ph)PFPPR ddPTM_HeLa_Curcumin_4h_R1 4 ETDVSPFPPR 10 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3 Q9H8V3-2 ECT2 Protein ECT2 1 0 ET(0.003)DVS(0.997)PFPPR;ET(0.003)DVS(0.997)PFPPR;ET(0.008)DVS(0.992)PFPPR;ET(0.409)DVS(0.591)PFPPR ;;; 121.61 0.0042881 28038500 9380.7 9052.5 9131 9454.9 8646.8 12420.2 14149.4 6379.03 10841.6 9146.2 TRUE FALSE FALSE 8638.207697 9834.957763 9469.402892 9415.778129 8543.692557 9844.110515 14546.39408 8323.966882 9652.303604 9464.029769 0.912740968 1.039193452 1.000567742 0.994901576 0.902754193 1.040160561 1.537019054 0.879537267 1.019893622 1 13.2082389 -4.983563235 24.97166504 0.967021572 1.228356155 0.248817906 0.153303142 176.520172 268175.9176 0.018241609 0.054705204 1.04E-05 4.983563235 0.261334583 VHGLPTT(ph)SPSGMNMAELAQQVVK ddPTM_HeLa_Curcumin_4h_R1 1 VHGLPTTSPSGMNMAELAQQVVK 23 0 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 0 VHGLPT(0.175)T(0.703)S(0.056)PS(0.065)GMNMAELAQQVVK 71.309 0.0018084 19828000 2877.2 2375.8 2487.4 2332.3 2300.6 3125.1 1392.6 776.71 3250.5 2235.2 TRUE FALSE FALSE 2649.466584 2581.153566 2579.585232 2322.649561 2273.166848 2476.919033 1431.672608 1013.525303 2893.928282 2312.873034 1.145530492 1.115994492 1.115316403 1.004227005 0.982832527 1.070927369 0.619001816 0.438210524 1.251226609 1 11.17547036 -4.666387415 3.134317564 1.06773201 0.462489847 0.88850904 0.079757705 0.049705025 0.930242961 0.009842418 0.046996161 2.16E-05 4.666387415 -0.605242162 down S(ph)LIAQDHR ddPTM_HeLa_Curcumin_4h_R1 2 SLIAQDHR 8 0 E9PB39;H0YAN8;O15013-7;O15013-4;O15013-5;O15013-6;O15013 E9PB39 ARHGEF10 Rho guanine nucleotide exchange factor 10 1 0 S(1)LIAQDHR;S(1)LIAQDHR ; 92.943 0.0090639 21901300 2220.86 1625.09 2094.1 2620.1 2301.09 2112.36 2472.7 5599.6 1916.41 1947.72 TRUE FALSE FALSE 2045.076588 1765.555538 2171.709188 2609.25872 2273.651005 1674.232725 2542.077307 7306.892263 1706.184618 2015.403125 1.014723339 0.876030962 1.077555731 1.294658467 1.128137084 0.830718532 1.261324484 3.625523932 0.846572379 1 10.97685272 -4.262872536 4.050859617 1.022587322 3.84916679 0.971392707 0.133878653 0.023151585 0.803614322 0.016792316 0.190488787 5.46E-05 4.262872536 2.826579467 up YYS(ph)DSDDELTVEQR ddPTM_HeLa_Curcumin_4h_R1 1 YYSDSDDELTVEQR 14 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 YYS(0.5)DS(0.5)DDELT(0.001)VEQR 171.11 4.54E-11 0 641.53 549.34 391 495.95 431.35 704.02 718.38 1147.7 736.7 678.46 TRUE FALSE FALSE 590.7522236 596.8225018 405.490804 493.8978903 426.206433 557.9983161 738.5358094 1497.628447 655.8858531 702.0364345 0.84148371 0.850130381 0.57759225 0.703521735 0.607100162 0.794828144 1.051990713 2.133263137 0.934261843 1 9.455402096 -4.262798464 3.071315183 0.848700575 2.332888897 0.894631588 0.1368011 0.103543413 1.455261145 0.02344938 0.371237999 5.46E-05 4.262798464 1.484188322 up ETEEQDS(ph)DSAEQGDPAGEGK ddPTM_HeLa_Curcumin_4h_R1 2 ETEEQDSDSAEQGDPAGEGK 20 0 H0Y626;O95361 H0Y626 TRIM16 Tripartite motif-containing protein 16 1 0 ET(0.029)EEQDS(0.659)DS(0.312)AEQGDPAGEGK;ET(0.005)EEQDS(0.825)DS(0.171)AEQGDPAGEGK ; 159.16 5.29E-06 40337000 14949.5 11670.7 15386.4 13569.7 18504.9 16034 14958.1 14735.3 11923.8 12541.2 TRUE FALSE FALSE 13766.2313 12679.4633 15956.63352 13513.55218 18284.24115 12708.36766 15377.78403 19228.02514 10615.78897 12977.00577 1.060817229 0.977071563 1.229608263 1.041345933 1.408972261 0.979298914 1.185002481 1.481699668 0.818046101 1 13.66366992 -1 0.274145079 1.011308293 3.652470838 0.446884737 0.146122651 32.99047646 0.419325981 0.055229785 41.98896487 0.1 1 2.641162545 ETEEQDS(ph)DSAEQGDPAGEGKEVLCDFCLDDTRR ddPTM_HeLa_Curcumin_4h_R1 2 ETEEQDSDSAEQGDPAGEGKEVLCDFCLDDTRR 33 2 H0Y626;O95361 H0Y626 TRIM16 Tripartite motif-containing protein 16 1 0 ET(0.016)EEQDS(0.653)DS(0.331)AEQGDPAGEGKEVLCDFCLDDTRR;ET(0.003)EEQDS(0.774)DS(0.223)AEQGDPAGEGKEVLCDFCLDDTRR ; 66.489 9.59E-06 215860000 6177.9 4801 5053.6 5477.2 5556.6 6053.5 4501.9 4948.5 6480.2 5244.3 TRUE FALSE FALSE 5688.912696 5215.977047 5240.890862 5454.536798 5490.341174 4797.935863 4628.211198 6457.27487 5769.338273 5426.539035 1.048350092 0.961197738 0.965788844 1.005159414 1.011757428 0.88416131 0.852884531 1.189943503 1.063170878 1 12.40581665 -7.251966117 23.94930731 1.022831988 0.974324223 0.068671086 0.086467067 818.3300814 2068813.283 0.013538001 0.016452723 5.60E-08 7.251966117 -0.048507765 ETEGDVTSVK ddPTM_HeLa_Curcumin_4h_R1 1 ETEGDVTSVK 10 0 P50990-2;P50990;P50990-3 P50990-2 CCT8 T-complex protein 1 subunit theta 0 0 130.66 0.0013653 4952800 1652.6 1655.7 1447.9 1704 1957.5 2000.2 1577 1540.6 1731.2 1474 FALSE FALSE TRUE 1521.794966 1798.81133 1501.560448 1696.9493 1934.158091 1585.335973 1621.246376 2010.321848 1541.291691 1525.22139 0.997753491 1.179377198 0.98448688 1.11259212 1.26811629 1.039413677 1.062958064 1.318052488 1.010536373 1 10.57480295 -6.523762354 0.524668613 0.990997249 1.177413545 0.311084041 0.094286349 0.773089961 0.435077433 0.026515503 0.059343544 2.99E-07 6.523762354 0.186416296 ETEGDVTSVK(ac)DAK ddPTM_HeLa_Curcumin_4h_R1 1 ETEGDVTSVKDAK 13 1 P50990-2;P50990;P50990-3 P50990-2 CCT8 T-complex protein 1 subunit theta 0 1 ETEGDVTSVK(1)DAK 184.87 5.65E-09 1222900 522.97 639.32 320.3 405.04 444.54 918.71 488.02 564.21 1190.1 555.97 FALSE TRUE FALSE 481.5763727 694.579972 332.1705998 403.3640518 439.2391508 728.15919 501.7125278 736.2350317 1059.549007 575.2899161 0.837102058 1.207356417 0.577396875 0.701149178 0.763509213 1.265725627 0.87210381 1.279763492 1.841765304 1 9.168145372 -5.265583092 24.96502833 0.890422589 1.112488258 0 0.357702983 403.3150298 2429899.056 0.027540058 0.063770886 5.43E-06 5.265583092 0.222065669 ETEIS(ph)LKDSTLDN ddPTM_HeLa_Curcumin_4h_R1 1 ETEISLKDSTLDN 13 1 O75475 O75475 PSIP1 PC4 and SFRS1-interacting protein 1 0 ETEIS(0.997)LKDS(0.002)T(0.002)LDN 139.78 0.0095823 7223300 3659.2 3311.2 3269.1 3934.5 4097.9 5732.5 5957.3 1978.3 3640.3 3202.3 TRUE FALSE FALSE 3369.570459 3597.405374 3390.255722 3918.220082 4049.035219 4543.514881 6124.445805 2581.474563 3240.968198 3313.579687 1.016897367 1.085655307 1.02313994 1.182473473 1.221951968 1.371180207 1.848286863 0.779059147 0.978086693 1 11.6941749 -5.85454137 1.514867077 1.014403208 1.373126418 0.230017976 0.243548445 0.342737184 1.582915259 0.034568794 0.079709346 1.40E-06 5.85454137 0.35872321 ETEK(ac)ILIK ddPTM_HeLa_Curcumin_4h_R1 1 ETEKILIK 8 1 H0YI89;E9PQI5;E9PQ80;E9PSI1;Q9BY43;Q9BY43-2 H0YI89 CHMP4A Charged multivesicular body protein 4a 0 1 ETEK(1)ILIK 95.099 0.017584 1153600 343.3 551.09 556.19 373.51 342.67 459.01 460.12 263.02 591.15 652.13 FALSE TRUE FALSE 316.1274428 598.723764 576.8028907 371.9645146 338.5838841 363.8061519 473.0297289 343.2135872 526.302324 674.791469 0.468481683 0.887272278 0.854786874 0.551228834 0.501760766 0.539138636 0.701001347 0.508621705 0.7799481 1 9.398297924 -9.483311997 1.121244306 1.00854769 0.618282364 0.28189664 0.153622235 0.36953515 0.801088632 0.116891647 0.026109479 3.29E-10 9.483311997 -0.390265325 ETENDDLTNVIQK ddPTM_HeLa_Curcumin_4h_R1 1 ETENDDLTNVIQK 13 0 O95373 O95373 IPO7 Importin-7 0 0 132.47 0.0015551 0 573.42 609.76 709.66 763.36 701.57 804.72 626.71 633.04 773.32 515.43 FALSE FALSE TRUE 528.0332019 662.4649374 735.9606239 760.2014186 693.204236 637.8120009 644.2937959 826.0509818 688.4887308 533.3411541 0.990047736 1.242103543 1.379905935 1.425356758 1.299738883 1.195879965 1.208033153 1.548822879 1.29089744 1 9.058914845 -7.160049403 3.375605654 0.994462974 1.331023506 0.338864211 0.134897196 0.095379724 2.049202857 0.016355583 0.020123961 6.92E-08 7.160049403 0.336560532 ETERAS(ph)PIKMDLAPSK ddPTM_HeLa_Curcumin_4h_R1 1 ETERASPIKMDLAPSK 16 2 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 ET(0.066)ERAS(0.934)PIKMDLAPSK 87.654 0.0053257 717740000 5255.8 5037.7 5528.4 5555.5 5268.7 6439.9 5115.5 2885.3 5567.4 4841.6 TRUE FALSE FALSE 4839.797884 5473.13634 5733.287367 5532.512813 5205.874194 5104.192147 5259.027162 3765.014688 4956.670149 5009.84524 0.966057364 1.09247613 1.144404087 1.104328088 1.039128744 1.0188323 1.049738447 0.751523152 0.989385882 1 12.29055032 -4.257385181 24.80492288 1.018915423 0.751523036 0.678435933 0.058168992 212.1409371 1297890.321 0.00981096 0.101208154 5.53E-05 4.257385181 -0.267392387 ETES(ph)APGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 ETESAPGSPR 10 0 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 2 0 ET(0.183)ES(0.817)APGS(1)PR;ET(0.387)ES(0.613)APGS(1)PR;ET(0.006)ES(0.994)APGS(1)PR ;; 152.96 0.0015637 778290000 48912 43621 46641 47040 44983 52057 43334 28227.7 47239 42204 TRUE FALSE FALSE 45040.56359 47391.40487 48369.55649 46845.36094 44446.6071 41259.7914 44549.83541 36834.19579 42056.99989 43670.58586 1.03137072 1.085201949 1.107600357 1.072698248 1.017769884 0.944795921 1.020133679 0.843455499 0.963050966 1 15.41437427 -3.334770947 1.02521611 1.030075171 9.34E-18 0.567924207 0.048305753 5.981624527 1.18353231 0.007359252 10.63536822 0.000462625 3.334770947 -1.030075171 TLEAEFNSPSPPT(ph)PEPGEGPR ddPTM_HeLa_Curcumin_4h_R1 1 TLEAEFNSPSPPTPEPGEGPR 21 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 0 TLEAEFNSPS(0.001)PPT(0.999)PEPGEGPR 91.079 0.00042205 6658200 1275.1 995.17 1293.2 975.82 1048.6 1288.8 1161.8 1703.4 1012.2 1013.1 TRUE FALSE FALSE 1174.17449 1081.18806 1341.12713 971.7823154 1036.09613 1021.488352 1194.396981 2222.758819 901.1641924 1048.30515 1.120069371 1.03136769 1.279328953 0.927003283 0.988353563 0.974418901 1.139360025 2.120335686 0.859639193 1 10.03384301 -4.262721113 4.274602792 1.05328503 2.200528082 0.896416881 0.110860599 0.039813071 1.677904132 0.01287204 0.138433775 5.46E-05 4.262721113 1.147243052 up ETESAPGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 5 ETESAPGSPR 10 0 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 0 ETESAPGS(1)PR;ETESAPGS(1)PR;ETESAPGS(1)PR;ETESAPGS(1)PR;ETESAPGS(1)PR ;;;; 151.13 0.00071048 1958703200 23328.5 19570.3 18607.6 19121.3 19740.8 22293.2 15712.8 13693.2 22621.4 16738.8 TRUE FALSE FALSE 21482.02461 21261.86953 19297.21402 19042.18113 19505.40385 17669.33902 16153.65888 17868.19364 20139.88902 17320.47205 1.240267848 1.227557163 1.114127488 1.099403126 1.126147359 1.020141886 0.93263387 1.031622787 1.162779453 1 14.08019063 -5.165930962 3.517750154 1.124598411 0.980827244 0.477284383 0.068447633 0.244998225 5.674221219 0.01405832 0.039059556 6.82E-06 5.165930962 -0.143771166 ETFAS(ph)DTNEALASLDESQEGHAEAK ddPTM_HeLa_Curcumin_4h_R1 1 ETFASDTNEALASLDESQEGHAEAK 25 0 Q9H814 Q9H814 PHAX Phosphorylated adapter RNA export protein 1 0 ET(0.033)FAS(0.934)DT(0.033)NEALASLDESQEGHAEAK 203.75 2.31E-22 9165700 1922.1 1595.1 1927.4 1489.9 2821.7 2744.6 2001.2 1785.7 1873 1239 TRUE FALSE FALSE 1769.963757 1732.973336 1998.83114 1483.735189 2788.05307 2175.339022 2057.348286 2330.15171 1667.536586 1282.055158 1.380567557 1.351715116 1.559083576 1.157309948 2.174674821 1.696759308 1.604726812 1.817512839 1.300674605 1 10.32424262 -7.164924619 0.199442175 0.804731391 2.034049329 0.453465199 0.239828582 1.46057719 0.258561514 0.610217224 0.720789896 6.84E-08 7.164924619 1.229317939 ETFASDT(ph)NEALASLDESQEGHAEAK ddPTM_HeLa_Curcumin_4h_R1 1 ETFASDTNEALASLDESQEGHAEAK 25 0 Q9H814 Q9H814 PHAX Phosphorylated adapter RNA export protein 1 0 ET(0.036)FAS(0.412)DT(0.552)NEALASLDESQEGHAEAK 181.22 1.82E-14 8352200 2868.9 2668.3 3264 2587.9 4105.2 4041.5 3563.9 2566.2 2712.9 2906.9 TRUE FALSE FALSE 2641.823538 2898.935962 3384.966711 2577.191956 4056.248171 3203.247343 3663.893442 3348.622567 2415.301657 3007.914559 0.878290751 0.963769384 1.125353345 0.856803578 1.348525064 1.064939605 1.218084281 1.113270507 0.802982136 1 11.55454787 -5.772968224 24.99991986 0.952836149 1.179820182 0.556209939 0.108117373 117.8613972 255578.775 0.014133084 0.02577701 1.69E-06 5.772968224 0.226984034 ETFASDTNEALAS(ph)LDESQEGHAEAK ddPTM_HeLa_Curcumin_4h_R1 2 ETFASDTNEALASLDESQEGHAEAK 25 0 Q9H814 Q9H814 PHAX Phosphorylated adapter RNA export protein 1 0 ETFASDTNEALAS(0.997)LDES(0.003)QEGHAEAK;ETFASDTNEALAS(1)LDESQEGHAEAK ; 113.75 5.87E-06 5210000 2061.65 1758.09 1813.22 1233.72 2303.2 2167.3 1874.2 1338.64 1939.29 1376.15 TRUE FALSE FALSE 1898.468227 1910.051466 1880.419528 1228.615194 2275.735844 1717.777549 1926.785008 1746.785174 1726.554739 1423.97111 1.333221028 1.34135549 1.320546123 0.862809073 1.598161527 1.206328933 1.353106811 1.226699869 1.212492814 1 10.47570416 -9.296806335 0.924722001 0.992579734 1.283017733 0.081373705 0.183903651 0.616912648 0.907754779 0.124235431 0.03018203 5.05E-10 9.296806335 0.290437999 ETFASDTNEALASLDES(ph)QEGHAEAK ddPTM_HeLa_Curcumin_4h_R1 2 ETFASDTNEALASLDESQEGHAEAK 25 0 Q9H814 Q9H814 PHAX Phosphorylated adapter RNA export protein 1 0 ETFASDTNEALASLDES(1)QEGHAEAK;ETFASDTNEALASLDES(1)QEGHAEAK ; 162.6 5.09E-10 81246000 8818.2 7561.9 8163.5 7406.7 9573.7 10834.8 7832.6 7471.7 7058.8 6131.7 TRUE FALSE FALSE 8120.230165 8215.516941 8466.046491 7376.053038 9459.53988 8587.540347 8052.361676 9749.786935 6284.4673 6344.776119 1.279829266 1.294847413 1.334333369 1.162539529 1.490917836 1.353482012 1.269132515 1.536663667 0.990494729 1 12.63135354 -12.76494389 0.140455395 9.06E-12 1.483512868 0.720123843 0.090755486 22.94923553 0.27413634 6.589016155 0.262485723 1.72E-13 12.76494389 1.483512868 ETFLTSPEELYR ddPTM_HeLa_Curcumin_4h_R1 2 ETFLTSPEELYR 12 0 G3V438;H0YJG7;O95433-2;O95433;H0YJ63 G3V438 AHSA1 Activator of 90 kDa heat shock protein ATPase homolog 1 0 0 ; ; 138.25 0.012005 9339500 1567.39 1656.76 1815.55 1895.25 1749.81 1971.29 1263.56 1762.95 2101.61 1551.77 FALSE FALSE TRUE 1443.329428 1799.962952 1882.83588 1887.407958 1728.944659 1562.422233 1299.012093 2300.465339 1871.068641 1605.693892 0.898882056 1.120987606 1.172599516 1.175446931 1.07675857 0.973051116 0.809003571 1.43269234 1.165271071 1 10.64898117 -7.254433945 24.59001596 0.95224986 1.095710721 0.001749109 0.165703675 588.9989821 2067467.015 0.024522103 0.029678528 5.57E-08 7.254433945 0.143460861 ETGEHLVHVK ddPTM_HeLa_Curcumin_4h_R1 3 ETGEHLVHVK 10 0 P21333-2;P21333;Q60FE5 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ;; ;; 111.46 0.0020337 33384100 17785.7 14397.2 16203.3 16264.6 19263.8 21034.8 15709.8 14588.6 18534.2 15797.5 FALSE FALSE TRUE 16377.94308 15641.62982 16803.80855 16197.30139 19034.09177 16671.94537 16150.57471 19036.59698 16501.04463 16346.46195 1.001925868 0.95688167 1.027978324 0.990875056 1.164416607 1.019911552 0.988016536 1.164569865 1.009456645 1 13.99669079 ETGEHLVHVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 ETGEHLVHVKK 11 1 P21333-2;P21333;Q60FE5 P21333-2;Q60FE5 FLNA Filamin-A 0 1 ; ETGEHLVHVK(1)K;ETGEHLVHVK(1)K 99.568 0.00093846 24658000 7437.2 8400.6 5618.1 6626 9759.2 15195.6 9875.6 10066.1 18386.8 8021.8 FALSE TRUE FALSE 6848.537772 9126.710432 5826.311728 6598.583368 9642.827914 12043.86127 10152.68276 13135.20755 16369.81404 8300.556953 0.825069668 1.099529885 0.701918168 0.794956701 1.161708542 1.450970259 1.223132714 1.58244894 1.972134416 1 13.01899243 -5.521481697 3.755174324 0.905584842 1.394222805 0.065378529 0.362594842 0.08620247 2.667033353 0.019564744 0.043296561 3.01E-06 5.521481697 0.488637964 ETGEHLVHVKK ddPTM_HeLa_Curcumin_4h_R1 3 ETGEHLVHVKK 11 1 P21333-2;P21333;Q60FE5 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ;; ;; 80.688 0.0036499 44671800 17279.8 14206.2 12972.8 14490.4 12716.2 19252.4 13807.4 14195.9 23128.7 18765 FALSE FALSE TRUE 15912.0856 15434.12063 13453.58338 14430.44256 12564.56762 15259.23522 14194.79848 18524.16456 20591.53948 19417.08235 0.81948901 0.794873315 0.692873581 0.743182848 0.647088342 0.785866535 0.731046932 0.954013802 1.060485767 1 14.24503881 -8.489734942 0.64862099 0.995152855 0.754789157 0.61268246 0.081091606 0.372023482 0.324257557 0.042933631 0.018831218 3.24E-09 8.489734942 -0.240363698 ETGTEHS(ph)PGVQPADVK ddPTM_HeLa_Curcumin_4h_R1 2 ETGTEHSPGVQPADVK 16 0 E9PJP1;E9PLK9;E9PNP3;K4DI89;Q9H7C9-3;Q9H7C9-2;Q9H7C9 E9PJP1 AAMDC Mth938 domain-containing protein 1 0 ET(0.001)GTEHS(0.999)PGVQPADVK;ET(0.039)GT(0.027)EHS(0.934)PGVQPADVK ; 107.18 0.00086974 20559600 6415.7 5764.3 5850.6 6628.5 6927.4 8445.4 6337.6 6668.9 6632.6 5837.6 TRUE FALSE FALSE 5907.890575 6262.540407 6067.428383 6601.073023 6844.795279 6693.728841 6515.415999 8702.21691 5905.020374 6040.456165 0.978053712 1.036766137 1.004465262 1.092810351 1.133158671 1.10814956 1.078629796 1.440655585 0.977578549 1 12.56044179 -1 0.527829009 0.997576802 15.8813494 0.819720635 0.055109161 31.43481037 0.280021387 0.010333424 528.3025045 0.1 1 14.88377259 ETGVPIAGR ddPTM_HeLa_Curcumin_4h_R1 1 ETGVPIAGR 9 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586 V9GZ78 MTHFD1 "C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed" 0 0 98.458 0.0060799 0 1674.8 1546.7 1311.6 1498.5 1428.9 1603.7 1266.9 1287.4 1639.6 1167.1 FALSE FALSE TRUE 1542.237813 1680.389856 1360.20905 1492.299604 1411.861301 1271.074543 1302.445804 1679.922334 1459.739982 1207.656638 1.27704992 1.39144671 1.126321014 1.235698589 1.169091657 1.052513192 1.078490163 1.391059578 1.208737596 1 10.23799461 -9.379288163 1.140584043 1.001680525 1.21227554 0.012614349 0.126809022 0.454242089 1.07004527 0.074158356 0.019718355 4.18E-10 9.379288163 0.210595015 ETHPDSLR ddPTM_HeLa_Curcumin_4h_R1 2 ETHPDSLR 8 0 P56597 P56597 NME5 Nucleoside diphosphate kinase homolog 5 0 0 ; ; 87.696 0.018911 22959900 11985.4 16316.6 9655.5 9534.7 8543.8 12288.4 8978.8 7573.7 9363.9 11260.7 FALSE FALSE TRUE 11036.74294 17726.9342 10013.34132 9495.247938 8441.920765 9739.647321 9230.720963 9882.886265 8336.703597 11652.00849 0.94719661 1.521362967 0.85936612 0.81490225 0.724503486 0.835877122 0.792199986 0.848170191 0.715473526 1 13.50829104 -6.541677306 24.99998455 1.023675139 0.80369024 0.268290922 0.189376246 231.551045 307935.9638 0.026056133 0.036852079 2.87E-07 6.541677306 -0.219984899 ETIEQEK ddPTM_HeLa_Curcumin_4h_R1 2 ETIEQEK 7 0 P63313;CON__P21752;P62328 P63313;P62328 TMSB10;TMSB4X Thymosin beta-10;Thymosin beta-4;Hematopoietic system regulatory peptide 0 0 ; ; 143.61 0.0028489 47039000 10230 14311.9 11284.2 8394.9 9883.1 10752.4 8925.7 8281.2 6606.1 8788.2 FALSE FALSE TRUE 9420.284705 15548.95686 11702.40238 8360.164128 9765.250487 8522.231035 9176.13112 10806.09976 5881.427358 9093.589296 1.035925903 1.709881143 1.286884859 0.91934701 1.073860955 0.937169115 1.009076925 1.18832063 0.646766328 1 13.15063413 ETIEQEK(ac)QAGES ddPTM_HeLa_Curcumin_4h_R1 1 ETIEQEKQAGES 12 1 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 1 ETIEQEK(1)QAGES 142.19 0.00010731 2977400 1075.4 1274.3 857.24 938.17 1758.9 2391 1327.7 1507.9 2072.2 953.67 FALSE TRUE FALSE 990.2809552 1384.444814 889.0100685 934.2881011 1737.926266 1895.079648 1364.951689 1967.651768 1844.884844 986.8099615 1.003517388 1.402949775 0.90089288 0.946776115 1.761155981 1.920409929 1.383196098 1.993952073 1.869544204 1 9.946628469 -5.758368518 24.99987525 1.02331273 1.748553584 0.365869683 0.332477347 26.93498624 219273.707 0.026850364 0.051920433 1.74E-06 5.758368518 0.725240854 ETIEQEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 ETIEQEKR 8 1 P63313 P63313 TMSB10 Thymosin beta-10 0 1 ; ETIEQEK(1)R;ETIEQEK(1)R 104.01 0.0033118 39664000 4665.7 10278.5 5202 3978 8507.1 11726.2 8125.4 8151.2 8685.1 4762.9 FALSE TRUE FALSE 4296.404922 11166.92774 5394.790696 3961.54009 8405.658389 9294.053938 8353.376856 10636.46336 7732.366259 4928.41042 0.871762811 2.265827475 1.094630973 0.803817002 1.705551622 1.885811681 1.694943429 2.158193504 1.568937162 1 12.26690669 -3.053342298 0.24834247 0.881203044 4.161525369 0.16763444 0.460438369 12.53699453 0.37569594 0.265977281 14.0059801 0.000884418 3.053342298 3.280322325 ETIEQEKQAGES ddPTM_HeLa_Curcumin_4h_R1 2 ETIEQEKQAGES 12 1 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 0 ; ; 155.11 0.00027148 24712000 12828.2 9928.9 9804.2 11129.3 8528.4 12006.9 9408.8 10787.9 13104.7 10451.6 FALSE FALSE TRUE 11812.83443 10787.10987 10167.55228 11083.24991 8426.7044 9516.533594 9672.785606 14077.08105 11667.1472 10814.79232 1.092284908 0.997440316 0.940152337 1.024823184 0.779183192 0.879955279 0.894403269 1.301650612 1.0788138 1 13.40071834 -7.003615505 5.708789643 1.043758818 0.956960783 0.07366113 0.130638239 0.318551142 37.77787722 0.020970617 0.026829753 9.92E-08 7.003615505 -0.086798035 ETIEQEKR ddPTM_HeLa_Curcumin_4h_R1 2 ETIEQEKR 8 1 P63313 P63313 TMSB10 Thymosin beta-10 0 0 ; ; 90.709 0.0065264 45028000 11850 15643.4 10966.3 8927.4 9248.5 12961.2 9367.7 9112.2 8500.9 10496.7 FALSE FALSE TRUE 10912.06 16995.54579 11372.72072 8890.460784 9138.217678 10272.90102 9630.53245 11890.46783 7568.372538 10861.45954 1.004658716 1.564757086 1.047071131 0.81853279 0.841343435 0.945812207 0.886670195 1.094739412 0.6968099 1 13.40693036 -6.353457414 9.113250479 1.056649801 0.913187286 0.106086154 0.210349128 0.644299823 59.54812768 0.028825606 0.044052478 4.43E-07 6.353457414 -0.143462516 ETIFELEDEVEQHR ddPTM_HeLa_Curcumin_4h_R1 2 ETIFELEDEVEQHR 14 0 F8WAN1;A0A494C1J1;Q69YQ0-2;Q69YQ0;C9J8U1 F8WAN1 SPECC1L-ADORA2A;SPECC1L Cytospin-A 0 0 ; ; 195.1 2.91E-06 4141000 2377.5 2691.1 2306.1 2553.8 2952.1 3262.6 2438.7 2295.3 2559.7 2065.63 FALSE FALSE TRUE 2189.318366 2923.706693 2391.566095 2543.233052 2916.898136 2585.899983 2507.123359 2995.126404 2278.907314 2137.410489 1.024285404 1.367873278 1.118908187 1.18986646 1.364687855 1.209828433 1.172972329 1.401287408 1.066200117 1 11.06164829 -7.321656091 9.019239308 1.011242014 1.251173849 0.574590919 0.090234085 0.194401294 27.99907331 0.014189545 0.016213408 4.77E-08 7.321656091 0.239931834 ETIFELEDQVEQHR ddPTM_HeLa_Curcumin_4h_R1 1 ETIFELEDQVEQHR 14 0 Q5M775-4;Q5M775;Q5M775-5;Q5M775-3;Q5M775-2;J3KSG2;J3KRN9;J3QQM0 Q5M775-4 SPECC1 Cytospin-B 0 0 133.48 0.00078088 2144300 1867.9 2134.8 1924.6 1998.2 2046 2387 2078.2 1044.5 1960.4 1718 FALSE FALSE TRUE 1720.053744 2319.3226 1995.927369 1989.931978 2021.602786 1891.909293 2136.508699 1362.963242 1745.349025 1777.700372 0.96757236 1.304675769 1.122758031 1.119385476 1.137201082 1.064245315 1.201838472 0.766700206 0.981801575 1 10.79579647 ETIHLPAS(ph)SPHPPPFP ddPTM_HeLa_Curcumin_4h_R1 1 ETIHLPASSPHPPPFP 16 0 Q5SZC3;Q5SZC6;Q9Y2T3-3 Q5SZC3 GDA 1 0 ETIHLPAS(0.5)S(0.5)PHPPPFP 75.143 0.0085716 1843500 1776.9 1508 1281 1489.9 1464 2022.5 1219.6 1196.1 1697.5 1530.3 TRUE FALSE FALSE 1636.25649 1638.3448 1328.474987 1483.735189 1446.542756 1603.010702 1253.818694 1560.785384 1511.288497 1583.477811 1.033330861 1.034649674 0.838960279 0.937010407 0.913522593 1.012335437 0.791813238 0.985669248 0.954410909 1 10.62888094 -6.782888244 24.99987447 1.017597626 0.913300684 0.328261185 0.06382284 160.0911761 186594.7996 0.008938944 0.011754055 1.65E-07 6.782888244 -0.104296942 ETLLNSATTSLNSK ddPTM_HeLa_Curcumin_4h_R1 1 ETLLNSATTSLNSK 14 0 P50991-2;P50991 P50991-2 CCT4 T-complex protein 1 subunit delta 0 0 168.31 5.38E-05 1635600 588.59 582.64 606.02 573.18 699.39 577.69 462.3 211.74 650.75 687.46 FALSE FALSE TRUE 542.0024804 633.0008054 628.4796343 570.808333 691.050231 457.8705821 475.2708938 276.2985513 579.3643531 711.3491838 0.7619359 0.889859467 0.883503698 0.802430573 0.971464151 0.643665014 0.668126013 0.3884148 0.814458449 1 9.474414107 -4.088681869 0.804382098 0.886811081 7.98E-12 0.756412278 0.08466042 1.295679 0.502590686 0.016367046 1.090812204 8.15E-05 4.088681869 -0.886811081 down ETLPAEQDLTTK ddPTM_HeLa_Curcumin_4h_R1 2 ETLPAEQDLTTK 12 0 P25786;P25786-2;F5GX11 P25786 PSMA1 Proteasome subunit alpha type-1 0 0 ; ; 158.06 1.70E-05 5327600 2124 1716.47 2041.77 2189.49 2115.94 3292 2376.9 2425.65 2305.85 1876.13 FALSE FALSE TRUE 1955.883159 1864.834018 2117.439792 2180.430471 2090.708797 2609.202092 2443.589417 3165.219519 2052.904024 1941.325378 1.007498888 0.960598383 1.090718648 1.123165903 1.076949192 1.34403131 1.258722234 1.63044256 1.0574755 1 10.92282623 -1 0.413515952 0.994723291 11.99474181 0.891518248 0.063939268 11.87044141 0.137207715 0.01273844 108.6117394 0.1 1 11.00001852 ETLVYLTHLDYVDTER ddPTM_HeLa_Curcumin_4h_R1 3 ETLVYLTHLDYVDTER 16 0 O14980 O14980 XPO1 Exportin-1 0 0 ;; ;; 197.47 1.04E-07 26499300 11914.9 10501.6 10685.8 10949.1 10535.7 12833.6 9860.8 8327.99 12211.8 12652.8 FALSE FALSE TRUE 10971.82309 11409.31151 11081.82515 10903.79553 10410.06866 10171.7667 10137.46751 10867.15581 10872.19609 13092.48386 0.838024565 0.8714398 0.846426489 0.83282864 0.79511793 0.776916497 0.774296735 0.83003011 0.830415085 1 13.67645121 -12.82936149 0.166978151 1.582473961 0.763180239 0.081645355 0.058437302 9.340790082 0.126414722 1.809262739 0.041050337 1.48E-13 12.82936149 -0.819293722 ETMQSLNDR ddPTM_HeLa_Curcumin_4h_R1 5 ETMQSLNDR 9 0 P05783;F8VZY9;CON__Q92764;C4AM86;CON__Q497I4;Q92764 P05783 KRT18;KRT35 "Keratin, type I cytoskeletal 18;Keratin, type I cuticular Ha5" 0 0 ;;;; ;;;; 158.76 0.00030202 463312800 10024.8 9653.7 10202.1 10375.3 12157.4 12869 9630.7 7182.56 9858.8 8705.5 FALSE FALSE TRUE 9231.326502 10488.12281 10580.1988 10332.36976 12012.43095 10199.82434 9900.911522 9372.48948 8777.314306 9008.015477 1.024790258 1.164310035 1.174531597 1.147019539 1.333526899 1.132305374 1.099122392 1.040461076 0.974389346 1 13.13699359 -7.290416843 4.799402303 1.010959177 1.16035755 0.49979415 0.071303517 0.127315197 7.639327332 0.012438434 0.014443204 5.12E-08 7.290416843 0.149398373 ETMVTSTTEPSR ddPTM_HeLa_Curcumin_4h_R1 1 ETMVTSTTEPSR 12 0 K7ELL7;P14314-2;P14314;A0A0C4DGP4 K7ELL7 PRKCSH Glucosidase 2 subunit beta 0 0 143.4 0.00010001 1675400 704.14 467.87 586.8 337.31 464.54 552.02 524.79 308.96 518.77 540.8 FALSE FALSE TRUE 648.406576 508.310598 608.5473242 335.9143006 459.0006639 437.5248295 539.514195 403.1604817 461.8622289 559.5927597 1.158711518 0.908358068 1.087482484 0.6002835 0.820240534 0.781862921 0.964119327 0.720453356 0.82535419 1 9.128233486 -6.286164069 24.73393607 1.062561083 0.790394531 0.367478097 0.128842318 344.1282681 344256.2013 0.016826307 0.025709966 5.17E-07 6.286164069 -0.272166552 VDLTLLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 VDLTLLSPK 9 0 E7EVA0;P27816-4;B5MEG9 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 VDLT(0.004)LLS(0.996)PK;VDLTLLS(1)PK ; 134.49 0.0032133 384660000 7862.3 6942.6 7403.2 7810.5 7379.3 7981.9 7442.5 12054.6 7765.5 6691.1 TRUE FALSE FALSE 7239.990659 7542.687408 7677.569105 7778.182221 7291.306667 6326.363965 7651.31652 15729.99205 6913.644078 6923.615227 1.04569512 1.089414585 1.108895982 1.123427857 1.053106856 0.913737081 1.105104237 2.271933308 0.998559835 1 12.75730984 -4.262679076 4.962990621 1.035929376 2.333188533 0.975464099 0.058271825 0.017893344 1.345329941 0.008389833 0.079409588 5.46E-05 4.262679076 1.297259157 up ETNLDSLPLVDT(ph)HSK ddPTM_HeLa_Curcumin_4h_R1 1 ETNLDSLPLVDTHSK 15 0 P08670 P08670 VIM Vimentin 1 0 ETNLDSLPLVDT(0.913)HS(0.087)K 92.897 0.0032594 0 2330.5 2022.9 1970.5 1856.2 2554.3 2935.6 2288.8 1570.6 2141.6 1987.8 TRUE FALSE FALSE 2146.038466 2197.750462 2043.528463 1848.519536 2523.841641 2326.723469 2353.017568 2049.46871 1906.671838 2056.875902 1.043348538 1.068489577 0.99351082 0.89870251 1.227026695 1.131192925 1.143976438 0.996398814 0.926974659 1 11.00623904 -5.756459865 24.9999998 1.01509131 1.126496689 0.431449203 0.072810437 97.4172694 489084.6904 0.009576334 0.018678098 1.75E-06 5.756459865 0.111405379 ETNLDSLPLVDT(ph)HSKR ddPTM_HeLa_Curcumin_4h_R1 1 ETNLDSLPLVDTHSKR 16 1 P08670 P08670 VIM Vimentin 1 0 ETNLDSLPLVDT(0.609)HS(0.391)KR 79.029 0.0069553 15628000 3825.3 3212 3164 3846.4 3510.8 4043.1 3331.5 2889.4 4090.1 3646.2 TRUE FALSE FALSE 3522.523469 3489.630968 3281.260623 3830.484616 3468.936003 3204.515485 3424.972924 3770.364759 3641.426263 3772.905179 0.933636893 0.92491881 0.869690721 1.0152613 0.919433656 0.849349595 0.907781341 0.999326667 0.96515181 1 11.88146013 -8.908976049 0.617867035 1.004504164 0.923322172 0.152253747 0.048965686 0.969467133 0.650665816 0.041268032 0.011271131 1.23E-09 8.908976049 -0.081181992 ETNLDSLPLVDTHS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 ETNLDSLPLVDTHSK 15 0 P08670 P08670 VIM Vimentin 1 0 ETNLDSLPLVDT(0.267)HS(0.733)K 77.357 0.0067803 0 1459.3 1247.1 1559 1713.1 1534.3 1649.4 1559.6 1257 1867.8 1560.8 TRUE FALSE FALSE 1343.794865 1354.893767 1616.777911 1706.011646 1516.004475 1307.295847 1603.358179 1640.253513 1662.907013 1615.037684 0.832051709 0.838923934 1.001077515 1.056329312 0.938680558 0.809452225 0.992768277 1.015613153 1.02963976 1 10.65735211 -6.730522453 24.99885224 0.9123425 0.965408781 0.051703095 0.084335091 454.2251656 367276.99 0.014701423 0.020789722 1.86E-07 6.730522453 0.05306628 ETNLDSLPLVDTHS(ph)KR ddPTM_HeLa_Curcumin_4h_R1 1 ETNLDSLPLVDTHSKR 16 1 P08670 P08670 VIM Vimentin 1 0 ETNLDSLPLVDT(0.175)HS(0.825)KR 98.76 0.0015142 15707000 2798.9 2032.6 1701 2408.8 2120.2 3319.1 2404.2 1886.6 2456.1 1963.7 TRUE FALSE FALSE 2577.364112 2208.288887 1764.040556 2398.833024 2094.918 2630.681246 2471.655381 2461.815655 2186.671975 2031.938429 1.268426284 1.086789273 0.868156501 1.180563835 1.030994822 1.294665827 1.216402695 1.211560164 1.076150706 1 10.98864097 -9.649000232 1.492425612 1.000208573 1.15821034 0.091425034 0.121524457 0.582712462 2.338928899 0.090364552 0.020541539 2.24E-10 9.649000232 0.158001767 ETNLDSLPLVDTHSK ddPTM_HeLa_Curcumin_4h_R1 4 ETNLDSLPLVDTHSK 15 0 P08670 P08670 VIM Vimentin 0 0 ;;; ;;; 220.25 2.86E-27 88400000 16995.7 15974.6 17063.9 15524.8 19293.8 21723.1 18276.5 16682.1 17086.3 14826.7 FALSE FALSE TRUE 15650.47241 17355.37324 17696.30314 15460.56249 19063.73404 17217.48419 18789.2894 21768.3955 15211.97564 15341.92672 1.020111274 1.131238179 1.153460283 1.007732782 1.242590607 1.122250452 1.224702069 1.418882771 0.991529676 1 13.90519206 -1 0.278291296 0.997985815 3.84281588 0.74749595 0.065284807 15.87520219 0.202169279 0.027022308 22.20867397 0.1 1 2.844830065 ETNLDSLPLVDTHSK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 ETNLDSLPLVDTHSKR 16 1 P08670 P08670 VIM Vimentin 0 1 ETNLDSLPLVDTHSK(1)R 146.86 0.00071659 32868000 2019.9 2011.5 1298.5 1368.7 2372 3896.4 2819.2 2607.8 3951.3 1774.4 FALSE TRUE FALSE 1860.022784 2185.365097 1346.623552 1363.036682 2343.715449 3088.242719 2898.299165 3402.906215 3517.852276 1836.060268 1.013051051 1.19024693 0.733431018 0.742370338 1.276491567 1.681994198 1.578542499 1.853373919 1.915978651 1 10.8423977 -5.421674686 3.22896353 0.982524328 1.694657682 0.372365076 0.3291374 0.074501026 1.466307885 0.021306145 0.050907949 3.79E-06 5.421674686 0.712133354 ETNLDSLPLVDTHSKR ddPTM_HeLa_Curcumin_4h_R1 4 ETNLDSLPLVDTHSKR 16 1 P08670 P08670 VIM Vimentin 0 0 ;;; ;;; 101.53 0.00072805 142056000 30277.2 22317.6 24146.4 24764 22248.4 35851.6 26342 26573.7 34878.1 28711.9 FALSE FALSE TRUE 27880.72767 24246.6339 25041.28683 24661.53313 21983.10236 28415.57403 27081.08562 34675.8988 31052.05969 29709.63639 0.938440555 0.816120183 0.842867496 0.830085323 0.73993172 0.956443009 0.911525314 1.167159986 1.045184777 1 14.85864333 -4.259797375 24.43520897 0.922804945 1.1671601 0.420449448 0.090691952 92.01291296 1369099.558 0.013709055 0.116330265 5.50E-05 4.259797375 0.244355154 ETPAAQS(ph)PTRGPSDTK ddPTM_HeLa_Curcumin_4h_R1 2 ETPAAQSPTRGPSDTK 16 1 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 0 ETPAAQS(0.739)PT(0.26)RGPS(0.001)DTK;ETPAAQS(0.971)PT(0.027)RGPS(0.002)DTK ; 180.78 1.10E-16 54553000 3644.94 3438.24 3266.16 3317.42 3852.04 4796.87 4937.65 1002.33 4600.25 3200.68 TRUE FALSE FALSE 3356.439153 3735.426145 3387.206763 3303.693395 3806.106939 3801.94509 5076.18717 1307.935803 4095.614084 3311.903392 1.01344718 1.127878958 1.022737188 0.997521064 1.149220399 1.147963766 1.532709916 0.394919673 1.236634527 1 11.69344487 -7.409065645 7.956290276 1.005904423 1.075685685 0 0.27346987 1.272994237 81.1569188 0.040824042 0.046560784 3.90E-08 7.409065645 0.069781261 ETPAATEAPS(ph)STPK ddPTM_HeLa_Curcumin_4h_R1 1 ETPAATEAPSSTPK 14 0 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 1 0 ETPAAT(0.004)EAPS(0.36)S(0.318)T(0.318)PK 93.478 0.0081598 14069000 3250.8 6694.6 3304 4468 3196.1 4752.8 4126.9 3736.4 5060.5 4108.4 TRUE FALSE FALSE 2993.49575 7273.251393 3426.449146 4449.5126 3157.988595 3767.015705 4242.689707 4875.61116 4505.375811 4251.166594 0.704158655 1.710883644 0.806002087 1.046656841 0.742852232 0.886113405 0.998005986 1.146887813 1.059797519 1 12.05364308 ETPAATEAPSS(ph)TPK ddPTM_HeLa_Curcumin_4h_R1 3 ETPAATEAPSSTPK 14 0 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 1 0 ETPAAT(0.035)EAPS(0.411)S(0.541)T(0.013)PK;ETPAATEAPSS(0.5)T(0.5)PK;ETPAATEAPSS(0.5)T(0.5)PK ;; 222.81 2.02E-14 87959000 13366.1 13881.9 11408.8 15026.2 12953.5 22602.6 21861 13824 17135.7 13637.1 TRUE FALSE FALSE 12308.15908 15081.78958 11831.62016 14964.02557 12799.03797 17914.56598 22474.36082 18038.87396 15255.95658 14110.98821 0.872239343 1.068797547 0.838468574 1.060451993 0.907026339 1.269547229 1.592685111 1.278356533 1.081140198 1 13.7845314 -5.111679516 3.6423592 0.948024141 1.437068911 0.746940241 0.109476055 0.067730709 1.62066905 0.013421419 0.037983119 7.73E-06 5.111679516 0.48904477 ETPAATEAPSST(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 ETPAATEAPSSTPK 14 0 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 1 0 ETPAATEAPS(0.006)S(0.073)T(0.921)PK;ETPAATEAPS(0.003)S(0.027)T(0.97)PK;ETPAATEAPSS(0.068)T(0.932)PK;ETPAATEAPSS(0.019)T(0.981)PK ;;; 223.58 3.96E-14 2740939100 15096.3 11883.6 11698 16049.8 14101.4 25735.1 23858.9 14073.9 18417.7 11812.6 TRUE FALSE FALSE 13901.41193 12910.76543 12131.53817 15983.39018 13933.25001 20397.35017 24528.31652 18364.96732 16397.32439 12223.08697 1.137307781 1.056260621 0.992510174 1.307639406 1.139912532 1.668756036 2.006720281 1.502481932 1.341504354 1 13.57732107 -5.253633746 3.116237382 1.078557015 1.77683753 0.723972564 0.163792045 0.071899311 1.426335384 0.019465224 0.052225879 5.58E-06 5.253633746 0.698280515 ETPAATEAPSSTPK ddPTM_HeLa_Curcumin_4h_R1 2 ETPAATEAPSSTPK 14 0 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 0 0 ; ; 312.69 3.09E-154 13948600 5953.4 4416.8 5039.2 5645.3 5204 8110.9 6968.6 6293 8160.9 5013.7 FALSE FALSE TRUE 5482.182108 4798.568511 5225.957185 5621.941244 5141.945699 6428.607911 7164.120161 8211.706731 7265.669688 5187.925702 1.056719472 0.924949351 1.007330769 1.083658781 0.991137112 1.23914803 1.380921889 1.582849717 1.400496095 1 12.3409421 -4.702050573 1.286302906 1.017685502 1.631710585 0.617285691 0.129829578 0.113451462 0.263241568 0.007071099 0.074083821 1.99E-05 4.702050573 0.614025083 ETPHS(ph)PGVEDAPIAK ddPTM_HeLa_Curcumin_4h_R1 6 ETPHSPGVEDAPIAK 15 0 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 ET(0.25)PHS(0.75)PGVEDAPIAK;ET(0.002)PHS(0.998)PGVEDAPIAK;ET(0.001)PHS(0.999)PGVEDAPIAK;ET(0.001)PHS(0.999)PGVEDAPIAK;ET(0.272)PHS(0.728)PGVEDAPIAK;ET(0.001)PHS(0.999)PGVEDAPIAK ;;;;; 143.43 0.00023961 5513785100 37367.2 49048.6 32267.4 39279.6 35096.8 44865.4 40026.3 54459.5 41800.9 35290.2 TRUE FALSE FALSE 34409.54669 53288.14243 33463.25823 39117.07142 34678.29358 35559.8103 41149.33025 71063.95085 37215.44585 36516.53182 0.942300514 1.459288157 0.916386539 1.071215405 0.949660109 0.973800318 1.126868522 1.946076128 1.019139661 1 15.15626213 -4.25975239 3.379358894 1.008861422 2.070330362 0.761658727 0.149978354 0.105883427 1.992992442 0.020197542 0.289912511 5.50E-05 4.25975239 1.06146894 ETPPNGNLS(ph)PAPR ddPTM_HeLa_Curcumin_4h_R1 3 ETPPNGNLSPAPR 13 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 0 ETPPNGNLS(1)PAPR;ETPPNGNLS(1)PAPR;ETPPNGNLS(1)PAPR ;; 141.06 0.00094671 97924000 6311.5 5510.11 5261.11 5282.74 4856.44 5770.5 5313.46 2744.44 6708.6 4861.69 TRUE FALSE FALSE 5811.938115 5986.379356 5456.091365 5260.881422 4798.530125 4573.633253 5462.541387 3581.207122 5972.683364 5030.633366 1.15530942 1.189985221 1.084573446 1.045769198 0.953862024 0.909156546 1.085855595 0.711879969 1.187262702 1 12.29652433 -5.77189915 2.158826061 1.086452071 0.919070468 0.466099036 0.101987696 0.266355397 2.531308682 0.015558697 0.033605321 1.69E-06 5.77189915 -0.167381602 T(ph)QTPPVSPAPQPT(ph)EER ddPTM_HeLa_Curcumin_4h_R1 2 TQTPPVSPAPQPTEER 16 0 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 2 0 T(0.862)QT(0.138)PPVS(0.051)PAPQPT(0.949)EER;T(0.345)QT(0.655)PPVS(0.333)PAPQPT(0.667)EER ; 176.48 8.26E-05 300050000 9166.2 8442.3 8595.1 7359.5 9041.8 8569.7 9041.1 19150.3 7688.4 8047.5 TRUE FALSE FALSE 8440.685598 9172.014794 8913.641967 7329.048339 8933.98244 6792.24762 9294.768933 24989.13831 6845.001755 8327.150026 1.013634385 1.101459054 1.070431293 0.880138861 1.072873962 0.815674943 1.116200489 3.000923273 0.82201014 1 13.0236071 -4.262612215 4.914983395 1.002152365 3.102995669 0.972857152 0.101016524 0.013915151 1.005570364 0.010395803 0.099185019 5.46E-05 4.262612215 2.100843305 up AKTQTPPVS(ph)PAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_HeLa_Curcumin_4h_R1 1 AKTQTPPVSPAPQPTEERLPSSPVYEDAASFK 32 2 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 2 0 AKT(0.003)QT(0.019)PPVS(0.95)PAPQPT(0.14)EERLPS(0.427)S(0.427)PVY(0.033)EDAAS(0.001)FK 56.252 0.00064838 82908000 6014.4 4916.6 4947.9 5047.4 4316.8 6612.8 6405.8 9624.8 7792.2 5933.1 TRUE FALSE FALSE 5538.353894 5341.568996 5131.273527 5026.515196 4265.324979 5241.230738 6585.529508 12559.35721 6937.415155 6139.274783 0.902118587 0.870065144 0.835811021 0.818747389 0.694760396 0.853721477 1.072688508 2.045739547 1.130005644 1 12.58385253 -4.26252246 3.199901492 0.905585526 2.210085165 0.907920734 0.10989581 0.068506581 1.091058239 0.014731017 0.221712442 5.46E-05 4.26252246 1.304499639 up ETPSQENGPTAK ddPTM_HeLa_Curcumin_4h_R1 1 ETPSQENGPTAK 12 0 O15355 O15355 PPM1G Protein phosphatase 1G 0 0 145.23 2.01E-16 0 203.24 254.56 351.81 369.7 235.54 358.66 181.38 194.09 198.05 219.18 FALSE FALSE TRUE 187.1533395 276.5630321 364.8483881 368.1702794 232.7313393 284.2698731 186.4690346 253.2671475 176.3244105 226.7964887 0.825203867 1.219432601 1.608703866 1.623350879 1.026168177 1.253413907 0.822186603 1.11671547 0.777456527 1 7.825254494 -7.226321688 9.508052748 0.917480449 1.244200468 0.336784869 0.235396873 0.498615461 131.6807678 0.04181214 0.051065117 5.94E-08 7.226321688 0.326720019 ETPSSANGPSR ddPTM_HeLa_Curcumin_4h_R1 1 ETPSSANGPSR 11 0 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 0 0 99.53 0.010967 571610 0 0 0 60.774 0 178.97 0 0 0 0 FALSE FALSE TRUE 0 0 0 60.52253329 0 141.8496046 0 0 0 0 0 ETQS(ph)PEQVK ddPTM_HeLa_Curcumin_4h_R1 6 ETQSPEQVK 9 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 ETQS(1)PEQVK;ET(0.046)QS(0.954)PEQVK;ETQS(1)PEQVK;ET(0.004)QS(0.996)PEQVK;ET(0.002)QS(0.998)PEQVK;ETQS(1)PEQVK ;;;;; 161.93 0.00059877 5156138000 37553.5 33200 36041.7 32689 39788 43419.6 37380.1 34548.3 33631.4 29374.5 TRUE FALSE FALSE 34581.10085 36069.66006 37377.43711 32553.74158 39313.55409 34413.88552 38428.885 45081.91763 29942.11956 30395.26169 1.137713542 1.186686939 1.229712627 1.071013697 1.293410614 1.132212181 1.264305121 1.483188995 0.985091685 1 14.89155882 -1 0.133447438 0.953916376 2.33239355 0.667350837 0.081712562 36.58176094 0.326956074 0.249971639 9.569797507 0.1 1 1.378477174 ETQS(ph)PEQVKSEK ddPTM_HeLa_Curcumin_4h_R1 2 ETQSPEQVKSEK 12 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 ET(0.385)QS(0.615)PEQVKSEK;ETQS(1)PEQVKSEK ; 183.28 0.00061992 1882496000 7892.1 5697.2 5851.9 6573.3 5870.3 8415.7 5977.2 6772 9143 7374.2 TRUE FALSE FALSE 7267.431957 6189.640582 6068.776562 6546.101426 5800.300507 6670.188956 6144.904145 8836.751626 8140.035775 7630.452901 0.952424719 0.811176042 0.79533635 0.857891597 0.760151538 0.874153742 0.805313161 1.158090056 1.066782782 1 12.89755297 -7.425701516 4.302540523 0.979840843 0.857135687 0.251144162 0.108195678 0.245138678 7.594024354 0.017384794 0.019587852 3.75E-08 7.425701516 -0.122705156 ETQST(ph)PQSAPQVR ddPTM_HeLa_Curcumin_4h_R1 1 ETQSTPQSAPQVR 13 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 0 ETQS(0.089)T(0.838)PQS(0.073)APQVR 173.33 0.00059855 10691000 3211.5 2194.9 2768.2 3248.2 2758 4655.7 3770 1215.8 3470.1 2068.2 TRUE FALSE FALSE 2957.306386 2384.617376 2870.791927 3234.759809 2725.112651 3690.055339 3875.776054 1586.491823 3089.438712 2140.069796 1.381873802 1.114270843 1.341447803 1.511520706 1.273375596 1.724268688 1.811051238 0.741327141 1.443615866 1 11.06344213 -9.97408065 0.302136513 0.704007825 1.438694367 0 0.317149991 6.96438535 0.585538693 1.840808624 0.144034085 1.06E-10 9.97408065 0.734686542 ETQTHENMSQLS(ph)EEEQNKDYQDCSK ddPTM_HeLa_Curcumin_4h_R1 1 ETQTHENMSQLSEEEQNKDYQDCSK 25 1 A0A087X0M4;Q9BWU0 A0A087X0M4 SLC4A1AP Kanadaptin 1 0 ETQT(0.001)HENMS(0.172)QLS(0.736)EEEQNKDY(0.053)QDCS(0.038)K 49.613 0.007908 10030000 1693.7 1383.6 1440.3 1445.9 1553.8 1927.5 1451.3 767.28 1763.5 1451 TRUE FALSE FALSE 1559.641858 1503.192219 1493.678785 1439.917249 1535.27195 1527.714773 1492.019572 1001.22014 1570.048462 1501.422142 1.03877638 1.001178933 0.994842652 0.959035576 1.022545164 1.017511818 0.993737557 0.666847858 1.045707545 1 10.55211395 -4.26099513 4.85002454 1.011658527 0.648137301 0.951566916 0.023122866 0.026685503 1.824894716 0.003319659 0.032578599 5.48E-05 4.26099513 -0.363521225 ETS(ph)PESSLIQDEIAVK ddPTM_HeLa_Curcumin_4h_R1 4 ETSPESSLIQDEIAVK 16 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 ET(0.047)S(0.952)PESSLIQDEIAVK;ET(0.019)S(0.98)PES(0.001)SLIQDEIAVK;ET(0.003)S(0.997)PESSLIQDEIAVK;ET(0.231)S(0.769)PESSLIQDEIAVK ;;; 205.12 2.19E-10 276659000 21266.7 17071.4 18277.2 17822 18938.5 22161.3 17155.2 18561.3 18881.8 17267.4 TRUE FALSE FALSE 19583.41825 18546.97575 18954.56911 17748.25729 18712.67076 17564.79657 17636.52874 24220.55492 16810.51378 17867.44086 1.096039349 1.038032021 1.060844094 0.993329566 1.047305593 0.983061688 0.987076374 1.355569335 0.940846197 1 14.12504539 -4.256032446 24.98868265 1.036337153 1.35556947 0.820714996 0.046734989 175.6966724 811974.4652 0.006149919 0.070554894 5.55E-05 4.256032446 0.319232317 ETS(ph)RSRGGGGAVS(ph)ER ddPTM_HeLa_Curcumin_4h_R1 2 ETSRSRGGGGAVSER 15 2 Q8N7J2-2;Q8N7J2 Q8N7J2-2 AMER2 APC membrane recruitment protein 2 2 0 ET(0.001)S(0.998)RS(0.003)RGGGGAVS(0.998)ER;ETS(0.999)RS(0.001)RGGGGAVS(0.999)ER ; 105.46 0.006851 1223530000 7765.7 11979.8 11314.7 9121.4 6522.7 8872.4 10262.1 6917.8 9289.8 14579.9 TRUE FALSE FALSE 7151.036651 13015.28053 11734.03274 9083.658064 6444.921063 7032.164227 10550.02691 9027.005374 8270.732182 15086.55044 0.474000778 0.862707521 0.77778103 0.602103052 0.427196468 0.466121414 0.699300145 0.598347874 0.548218906 1 13.88097535 -9.454207957 1.020419072 1.015747045 0.604667845 0 0.190941539 0.381829299 0.665436702 0.120838834 0.02565663 3.51E-10 9.454207957 -0.4110792 DQHLNNSSSS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 2 DQHLNNSSSSPQR 13 0 A0A5H1ZRS1;A0A4W8VX11;E9PGW9;E7EV93 A0A5H1ZRS1 PCM1 1 0 DQHLNNSSS(0.008)S(0.992)PQR;DQHLNNSSS(0.002)S(0.998)PQR ; 258.41 2.17E-36 16682700 6666.5 5022.5 4862 4671.9 6722.6 7103 1890.35 334.64 7046.8 4714.7 TRUE FALSE FALSE 6138.839491 5456.62252 5042.189997 4652.568916 6642.437386 5629.757733 1943.388133 436.6701955 6273.78367 4878.535474 1.258336549 1.118496022 1.03354583 0.953681477 1.361563818 1.1539852 0.398354823 0.08950846 1.285997346 1 12.2522324 -4.664351936 3.650381787 1.125648706 0.15084615 0.8901242 0.128347584 0.053311537 1.32142363 0.019151828 0.084315204 2.17E-05 4.664351936 -0.974802556 down ETSFGSSENIT(ph)MTSLSK ddPTM_HeLa_Curcumin_4h_R1 1 ETSFGSSENITMTSLSK 17 0 Q9UMZ2-6;Q9UMZ2-9;Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;A0A087WZS7 Q9UMZ2-6 SYNRG Synergin gamma 1 0 ETSFGSS(0.009)ENIT(0.882)MT(0.107)S(0.002)LSK 137.01 0.0093529 7823800 1803.9 1372.4 1550.3 1522.1 1646.4 1907.3 1834.3 709 1534.5 1790 TRUE FALSE FALSE 1661.119412 1491.024141 1607.755482 1515.801954 1626.767755 1511.70448 1885.765521 925.1708362 1366.169189 1852.202367 0.896834731 0.805000667 0.868023662 0.818378154 0.878288347 0.816165937 1.018120674 0.499497708 0.737591752 1 10.85502602 -1.000019805 0.053388276 1.30167052 3.80E-08 0 0.141338977 339.0468848 1.376048274 7.632742944 35.76929367 0.09999544 1.000019805 -1.301670482 ETSHGS(ph)PTVTK ddPTM_HeLa_Curcumin_4h_R1 2 ETSHGSPTVTK 11 0 Q8NI08-2;Q8NI08;Q8NI08-7 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 0 ET(0.001)S(0.001)HGS(0.989)PT(0.008)VT(0.001)K;ET(0.16)S(0.195)HGS(0.634)PT(0.011)VTK ; 84.753 0.010851 55728000 11410.2 14134.7 10705.3 9594.4 10593.3 16516.1 10666.3 3228.9 10732.5 11015.9 TRUE FALSE FALSE 10507.07063 15356.44049 11102.04784 9554.700915 10466.98182 13090.47469 10965.56767 4213.376746 9555.171601 11398.70171 0.921777839 1.347209611 0.973974767 0.838227121 0.918260876 1.148418041 0.962001459 0.369636548 0.838268414 1 13.47658189 -4.263690844 5.643413875 0.990464263 0.349587363 0.627367199 0.14453897 0.065316389 8.529605641 0.018671176 0.160784609 5.45E-05 4.263690844 -0.640876899 ETSSLES(ph)FVR ddPTM_HeLa_Curcumin_4h_R1 1 ETSSLESFVR 10 0 A0A087X2H1;Q9ULT8;H0YJP0 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 0 ETSSLES(1)FVR 199.33 1.68E-05 3692700 1940.2 1790 1601 2120.5 1894.7 1972 1456.1 1350.2 1934.1 1794.2 TRUE FALSE FALSE 1786.631123 1944.719624 1660.334468 2111.725933 1872.10694 1562.984971 1496.954247 1761.869764 1721.934069 1856.548316 0.962340224 1.047492062 0.894312555 1.137447334 1.008380403 0.841876808 0.806310417 0.949002915 0.927492193 1 10.85840715 -5.262238918 24.97414909 0.993543714 0.859788079 0.416848833 0.070854594 46.08493144 1439521.78 0.009089076 0.021522559 5.47E-06 5.262238918 -0.133755635 ETSVSKEDT(ph)DHEEK ddPTM_HeLa_Curcumin_4h_R1 1 ETSVSKEDTDHEEK 14 1 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 1 0 ETSVS(0.001)KEDT(0.999)DHEEK 78.021 0.017288 14715000 2435.9 1963.6 2832.8 2206.2 3300.4 2823.6 2244.7 2141.9 1793.1 2018.8 TRUE FALSE FALSE 2243.095945 2133.324834 2937.78606 2197.071329 3261.044886 2237.953531 2307.680241 2794.95545 1596.401416 2088.95315 1.073789494 1.02124111 1.40634368 1.051757111 1.561090485 1.071327776 1.104706556 1.337969428 0.764211211 1 11.02856442 -6.791830841 24.9919345 1.034798298 1.244930346 0.379980096 0.172602631 167.9550479 138114.5951 0.022376414 0.029410261 1.61E-07 6.791830841 0.210132048 ETSVSKEDT(ph)DHEEKASNEDVTK ddPTM_HeLa_Curcumin_4h_R1 1 ETSVSKEDTDHEEKASNEDVTK 22 2 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 1 0 ET(0.001)S(0.001)VS(0.008)KEDT(0.811)DHEEKAS(0.177)NEDVT(0.002)K 53.188 0.0082464 37459000 3372.4 2834 2596.5 2678.2 3200.9 3339.7 2606.3 2652 2887.5 2603.3 TRUE FALSE FALSE 3105.470981 3078.958332 2692.728574 2667.118318 3162.731358 2647.008574 2679.425764 3460.582592 2570.748474 2693.764481 1.152836858 1.142994628 0.999615443 0.990108206 1.174093496 0.982642912 0.994677071 1.284664126 0.95433305 1 11.395408 -9.626654621 1.468692984 1.000382507 1.092108931 0.16879003 0.096472609 0.734142244 2.863541101 0.064835716 0.015076902 2.36E-10 9.626654621 0.091726425 ETSVSKEDTDHEEKAS(ph)NEDVTK ddPTM_HeLa_Curcumin_4h_R1 1 ETSVSKEDTDHEEKASNEDVTK 22 2 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 1 0 ETSVSKEDT(0.14)DHEEKAS(0.858)NEDVT(0.001)K 73.294 0.00054079 30269000 1916.6 1498.9 1574.4 1783.2 2190.8 2199.1 1881.4 2114 2035 1743.4 TRUE FALSE FALSE 1764.899088 1628.458237 1632.748649 1775.821591 2164.676141 1742.981871 1934.18702 2758.548868 1811.765591 1803.98302 0.978334645 0.902701533 0.905079832 0.984389305 1.199942636 0.966185297 1.072175846 1.529143477 1.004314104 1 10.81697004 -4.252327017 2.955304669 0.990675946 1.626443746 0.809841845 0.077533162 0.127811097 1.569874058 0.010831959 0.19383199 5.59E-05 4.252327017 0.6357678 ETT(ph)MY(ph)RSRWES(ph)SNK ddPTM_HeLa_Curcumin_4h_R1 1 ETTMYRSRWESSNK 14 2 P40222 P40222 TXLNA Alpha-taxilin 3 0 ET(0.46)T(0.545)MY(0.68)RS(0.374)RWES(0.511)S(0.43)NK 52.372 0.0093475 0 160.13 240.78 172.4 170.61 114.04 197.94 192.64 185.58 222.69 0 TRUE FALSE FALSE 147.4555415 261.5919503 178.7892957 169.904061 112.6801475 156.8850128 198.0449599 242.1624877 198.2614641 0 0 ETTDTDTADQVIASFK ddPTM_HeLa_Curcumin_4h_R1 1 ETTDTDTADQVIASFK 16 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 0 145 0.0031797 6184400 3214.4 2194.4 2601.8 2782.2 2826.8 3589.8 3394.5 2786.9 3041.4 2419.2 FALSE FALSE TRUE 2959.976848 2384.074158 2698.224997 2770.687994 2793.092256 2845.235015 3489.740534 3636.612981 2707.766029 2503.26702 1.18244551 0.952385079 1.077881415 1.106828785 1.115778794 1.136608677 1.394074426 1.452746731 1.081692847 1 11.28959647 -4.760550572 2.494201747 1.080512331 1.455256501 0.843443988 0.059602563 0.103595771 1.245347341 0.01093206 0.052939722 1.74E-05 4.760550572 0.374744171 ETTKAEIIT(ph)GDT(ph)GELS(ph)GTTIISENS(ph)TTAGIT(ph)AATGK ddPTM_HeLa_Curcumin_4h_R1 1 ETTKAEIITGDTGELSGTTIISENSTTAGITAATGK 36 1 Q7Z5P9-2;Q7Z5P9 Q7Z5P9-2 MUC19 Mucin-19 5 0 ET(0.148)T(0.148)KAEIIT(0.667)GDT(0.476)GELS(0.476)GT(0.476)T(0.476)IIS(0.337)ENS(0.36)T(0.36)T(0.076)AGIT(0.499)AAT(0.499)GK 40.112 0.0085202 3047500 1808.7 1634.1 1613 1517.7 1821.3 2258.6 1816.1 1032.3 1653.8 1588.1 TRUE FALSE FALSE 1665.539486 1775.344323 1672.779199 1511.42016 1799.582187 1790.1409 1867.054878 1347.043518 1472.382278 1643.286357 1.013541845 1.080362114 1.017947476 0.919754584 1.095111743 1.089366374 1.13617135 0.819725371 0.895998602 1 10.68236819 ETTSGTSTEPVKNS(ph)SPAPPQPAPGK ddPTM_HeLa_Curcumin_4h_R1 1 ETTSGTSTEPVKNSSPAPPQPAPGK 25 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 0 ETTSGTSTEPVKNS(0.5)S(0.5)PAPPQPAPGK 100.64 1.71E-06 22459000 2933.9 2643 2485.5 2764 3049.6 3022.1 2496.3 2038 2777.5 2590 TRUE FALSE FALSE 2701.678719 2871.449143 2577.614816 2752.5633 3013.235512 2395.282394 2566.33946 2659.376818 2472.815199 2680.002307 1.008088206 1.071435325 0.961795745 1.027074974 1.124340641 0.893761318 0.957588526 0.992303929 0.922691444 1 11.38801853 -5.220070449 24.99947852 1.014612261 0.948855017 0.235937921 0.056496921 497.2541505 300492.6704 0.006570037 0.01675021 6.02E-06 5.220070449 -0.065757244 ETTSGTSTEPVKNSS(ph)PAPPQPAPGK ddPTM_HeLa_Curcumin_4h_R1 1 ETTSGTSTEPVKNSSPAPPQPAPGK 25 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 0 ETTSGTSTEPVKNS(0.278)S(0.722)PAPPQPAPGK 121.46 1.45E-08 61192000 8120.3 6731.8 6896.9 7186.9 7371 8801.2 6689.1 5694.5 6720.4 6559.2 TRUE FALSE FALSE 7477.569686 7313.666796 7152.505181 7157.162512 7283.105639 6975.73191 6876.778143 7430.726836 5983.188934 6787.131712 1.101727505 1.077578439 1.053833266 1.054519467 1.07307563 1.027787909 1.013208294 1.09482579 0.881548965 1 12.7285863 ETVEEQASTTER ddPTM_HeLa_Curcumin_4h_R1 2 ETVEEQASTTER 12 0 A0A669KAX4;K4DI93;Q13620-1;Q13620;Q13620-3 A0A669KAX4 CUL4B Cullin-4B 0 0 ; ; 211.63 5.41E-21 1486790 308.83 136.57 404.45 347.93 65.871 435.59 116.79 196.528 534.01 365.61 FALSE FALSE TRUE 284.3857796 148.3745023 419.4392728 346.4903578 65.08553135 345.2437239 120.0668131 256.4484825 475.430439 378.3149203 0.75171706 0.392198389 1.10870402 0.91587812 0.172040614 0.912582892 0.317372661 0.67787039 1.256705495 1 8.563443865 -13.52287871 0.059564387 2.445082526 0.029906053 0.299707626 0.284560271 324.4277954 1.51774934 69.20885943 13.17642717 3.00E-14 13.52287871 -2.415176472 ETVFT(ph)KSPYQEFTDHLVK ddPTM_HeLa_Curcumin_4h_R1 1 ETVFTKSPYQEFTDHLVK 18 1 P15880;H0YEN5;E9PQD7 P15880 RPS2 40S ribosomal protein S2 1 0 ET(0.027)VFT(0.781)KS(0.18)PY(0.01)QEFT(0.002)DHLVK 74.047 0.0088307 50524000 2034.4 1702.1 1527.1 2159.4 1779 3120.8 1905.2 1819 2497.1 1967.8 TRUE FALSE FALSE 1873.375093 1849.22194 1583.695669 2150.464975 1757.786587 2473.510901 1958.654784 2373.604726 2223.174377 2036.180904 0.920043543 0.908181555 0.777777489 1.056126679 0.863276236 1.21477954 0.961925721 1.165714069 1.091835393 1 10.99165003 -5.269351018 24.9964109 0.944595296 1.098918373 0.349259747 0.10498132 455.4690591 1439031.672 0.012829418 0.029185386 5.38E-06 5.269351018 0.154323077 ETVNS(ph)PAIYK ddPTM_HeLa_Curcumin_4h_R1 1 ETVNSPAIYK 10 0 Q9Y3A2 Q9Y3A2 UTP11L Probable U3 small nucleolar RNA-associated protein 11 1 0 ET(0.022)VNS(0.978)PAIYK 105.66 0.0094754 18955000 1983.6 1524.9 1830 2254.8 1600 2402.5 2158.9 782.2 2255 1935.4 TRUE FALSE FALSE 1826.595967 1656.705561 1897.82141 2245.470235 1580.921045 1904.194418 2219.472924 1020.689179 2007.632142 2002.655006 0.912087185 0.827254598 0.947652693 1.121246659 0.789412575 0.950834973 1.108265236 0.509668004 1.002485269 1 10.9676982 -4.248776294 24.65828443 0.954799516 0.509667664 0.645136596 0.100541087 791.707334 1541625.406 0.013140727 0.311171107 5.64E-05 4.248776294 -0.445131852 ETVQTTEDQILKR ddPTM_HeLa_Curcumin_4h_R1 1 ETVQTTEDQILKR 13 1 P18206;P18206-2 P18206 VCL Vinculin 0 0 84.297 0.0085481 3869100 1344.1 1356 1459.1 1404 1349.2 1799.1 1268.3 1367.7 1649.2 1178.8 FALSE FALSE TRUE 1237.713067 1473.206598 1513.17553 1398.19062 1333.111671 1425.94638 1303.885085 1784.705434 1468.286886 1219.763212 1.014715852 1.207780808 1.240548587 1.146280365 1.092926609 1.169035404 1.06896574 1.463157288 1.203747474 1 10.2523854 -1 0.142642699 0.936364204 2.176990773 0.078520519 0.122311059 49.47163743 0.463643655 0.264326438 12.61378759 0.1 1 1.240626569 ETVQTTQS(ph)PTPVEK ddPTM_HeLa_Curcumin_4h_R1 3 ETVQTTQSPTPVEK 14 0 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 0 ETVQTTQS(0.926)PT(0.074)PVEK;ETVQT(0.005)TQS(0.985)PT(0.011)PVEK;ETVQT(0.093)T(0.093)QS(0.649)PT(0.166)PVEK ;; 256.35 1.00E-38 51045600 8151 7283.7 8492.7 7679.9 10172.4 11186.6 9790.4 8074.3 6682.4 5845.1 TRUE FALSE FALSE 7505.839749 7913.270572 8807.446933 7648.122609 10051.10077 8866.373061 10065.09227 10536.1169 5949.357439 6048.21679 1.241000449 1.308364241 1.456205563 1.26452521 1.661828787 1.46594829 1.664142114 1.742020378 0.983654794 1 12.56229414 -1.000000008 0.104144011 0.725027954 3.782403009 0.881724571 0.087253295 23.38026822 0.172401275 0.557676815 10.27977782 0.099999998 1.000000008 3.057375055 ETVSEAPPLLFS(ph)DEEEKEAQLGVK ddPTM_HeLa_Curcumin_4h_R1 4 ETVSEAPPLLFSDEEEKEAQLGVK 24 1 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q641Q2;F8W7U3;E7ESD2;Q641Q2-2 A0A0A0MR88;Q641Q2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 0 ETVSEAPPLLFS(1)DEEEKEAQLGVK;ETVSEAPPLLFS(1)DEEEKEAQLGVK;ETVSEAPPLLFS(1)DEEEKEAQLGVK;ETVSEAPPLLFS(1)DEEEKEAQLGVK ;;; 154.72 5.99E-08 106388000 19662.4 16541.9 19945.4 19257.5 19843.9 23479.8 17409.9 9277.5 20686.5 17263.4 TRUE FALSE FALSE 18106.10029 17971.70813 20684.59407 19177.81757 19607.27445 18609.82481 17898.37494 12106.16704 18417.24271 17863.30187 1.013592024 1.006068658 1.15793789 1.073587499 1.097628792 1.041790871 1.001963415 0.677711609 1.031009992 1 14.12471115 -4.260870905 4.139436933 1.030396112 0.648353778 0.831196087 0.049587666 0.07822958 2.928841891 0.007840587 0.088621147 5.48E-05 4.260870905 -0.382042334 ETVSEESNVLCLSK ddPTM_HeLa_Curcumin_4h_R1 2 ETVSEESNVLCLSK 14 0 P13639 P13639 EEF2 Elongation factor 2 0 0 ; ; 305.3 3.68E-235 5547500 3406.4 3052.79 3101.4 3147.8 3035.1 4188.3 3048.7 2763.6 3641.9 3656.5 FALSE FALSE TRUE 3136.779846 3316.659565 3216.340612 3134.775238 2998.908415 3319.599368 3134.238317 3606.208918 3242.392682 3783.563103 0.829054455 0.876596868 0.850082455 0.828524635 0.79261488 0.877373861 0.828382726 0.953125089 0.856968047 1 11.88552979 -9.294843553 0.827741221 1.008474236 0.850265182 0 0.059894639 0.335407662 0.37663417 0.035049443 0.00765686 5.07E-10 9.294843553 -0.158209055 ETVVEVPQVTWEDIGGLEDVKR ddPTM_HeLa_Curcumin_4h_R1 2 ETVVEVPQVTWEDIGGLEDVKR 22 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 ; ; 208.62 1.14E-17 34955000 4998.4 3822.2 4129.3 3806.9 4272.3 5996 4363 4448.8 5076.7 4611.1 FALSE FALSE TRUE 4602.771366 4152.573937 4282.335491 3791.148056 4221.355613 4752.362011 4485.414038 5805.21864 4519.798711 4771.335382 0.964671522 0.870316925 0.897512991 0.794567506 0.884732528 0.996023467 0.940075195 1.216686352 0.947281704 1 12.22017738 -4.260217425 24.47268109 0.949282108 1.216686464 0.629291327 0.064885639 48.21287795 965423.9105 0.010575551 0.087733824 5.49E-05 4.260217425 0.267404356 ETYYLSDS(ph)PLLGPPVGEPR ddPTM_HeLa_Curcumin_4h_R1 2 ETYYLSDSPLLGPPVGEPR 19 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 0 ETYYLS(0.02)DS(0.98)PLLGPPVGEPR;ET(0.005)Y(0.083)Y(0.012)LS(0.227)DS(0.673)PLLGPPVGEPR ; 143.69 0.00015978 16439200 3494 2587.7 2660.1 3056.6 2807.7 5612.5 4817.2 2026.86 3116.5 2564.21 TRUE FALSE FALSE 3217.446213 2811.369257 2758.685646 3043.952599 2774.220011 4448.404234 4952.357667 2644.840283 2774.627747 2653.316107 1.21261323 1.059568157 1.039712396 1.147225765 1.045567094 1.676545144 1.866478576 0.996805574 1.045720764 1 11.37358085 -5.267511137 24.96332777 1.095187777 1.548596652 0.461286523 0.213706819 281.6455355 1157955.156 0.028732348 0.06583493 5.40E-06 5.267511137 0.453408875 RTDALTS(ph)SPGR ddPTM_HeLa_Curcumin_4h_R1 1 RTDALTSSPGR 11 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 0 RTDALT(0.005)S(0.498)S(0.498)PGR 90.229 0.0080722 475590000 1614.2 1349.3 1290.2 1257.6 1619.4 1470.2 1317.9 1898.5 1168.2 1032.2 TRUE FALSE FALSE 1486.434367 1465.92748 1338.015947 1252.396384 1600.089713 1165.263947 1354.876727 2477.34391 1040.051383 1068.068873 1.39170273 1.372502763 1.252743134 1.172580173 1.498114731 1.091000755 1.268529363 2.319460826 0.973768086 1 10.06078897 -4.26248011 5.478097365 1.221947519 2.359395432 0.806598517 0.16099561 0.051012537 5.828613463 0.024375093 0.216712636 5.46E-05 4.26248011 1.137447913 up EVAATEEDVTRLPS(ph)PTSPFSSLSQDQAATSK ddPTM_HeLa_Curcumin_4h_R1 3 EVAATEEDVTRLPSPTSPFSSLSQDQAATSK 31 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 EVAATEEDVTRLPS(0.564)PT(0.17)S(0.234)PFS(0.022)S(0.007)LS(0.002)QDQAATSK;EVAAT(0.003)EEDVT(0.01)RLPS(0.667)PT(0.077)S(0.077)PFS(0.043)S(0.054)LS(0.068)QDQAATSK;EVAAT(0.001)EEDVT(0.004)RLPS(0.536)PT(0.078)S(0.294)PFS(0.041)S(0.016)LS(0.03)QDQAATSK ;; 93.494 2.22E-08 371409000 8727.3 7912.2 8251 8330.2 8518.9 8987.9 7548.8 6971.6 9722 7882.9 TRUE FALSE FALSE 8036.524996 8596.095312 8556.789318 8295.73184 8417.317681 7123.708225 7760.599011 9097.208747 8655.520923 8156.830188 0.985250987 1.05385243 1.049033647 1.017028876 1.031934892 0.873342715 0.951423388 1.115287255 1.06113781 1 12.9937929 -4.247877441 24.16017183 0.99482597 1.115287383 0.270128613 0.054268144 1316.588246 2345397.482 0.007029402 0.178031296 5.65E-05 4.247877441 0.120461413 EVAATEEDVTRLPSPTS(ph)PFSSLSQDQAATSK ddPTM_HeLa_Curcumin_4h_R1 1 EVAATEEDVTRLPSPTSPFSSLSQDQAATSK 31 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 EVAATEEDVTRLPS(0.278)PT(0.278)S(0.402)PFS(0.032)S(0.009)LS(0.001)QDQAATSK 110.33 3.14E-11 439090000 3151.1 2698.9 2748 2748.9 2962.1 2975.4 2301.2 2564.3 2944.5 2470.9 TRUE FALSE FALSE 2901.68711 2932.18089 2849.843297 2737.52578 2926.778892 2358.2685 2365.765479 3346.143265 2621.495717 2556.763591 1.134906301 1.146833012 1.114629177 1.07069961 1.144720185 0.922364707 0.925296921 1.308741753 1.025317994 1 11.32010305 -4.23820693 23.80138563 1.063353186 1.308742284 0.467055066 0.081111104 2653.634297 2718539.124 0.01226983 0.861813177 5.78E-05 4.23820693 0.245389098 EVADIFNAPS(ph)DDEEFVGFR ddPTM_HeLa_Curcumin_4h_R1 4 EVADIFNAPSDDEEFVGFR 19 0 Q96GN5-5;Q96GN5-2;Q96GN5 Q96GN5-5 CDCA7L Cell division cycle-associated 7-like protein 1 0 EVADIFNAPS(1)DDEEFVGFR;EVADIFNAPS(1)DDEEFVGFR;EVADIFNAPS(1)DDEEFVGFR;EVADIFNAPS(1)DDEEFVGFR ;;; 235.02 1.67E-25 43699400 14091.4 12150 13652.1 12210.4 15426.6 14175.4 11067.5 7086.72 11083.5 11349.4 TRUE FALSE FALSE 12976.05082 13200.19186 14158.05884 12159.8766 15242.64787 11235.26225 11378.02426 9247.428305 9867.66778 11743.79081 1.104928642 1.124014561 1.205578256 1.03543028 1.297932509 0.956698091 0.968854474 0.787431287 0.840245534 1 13.51961055 -4.458726495 1.689025269 1.080526061 0.756452598 0.356267939 0.119520597 0.449503184 1.653658423 0.014014629 0.207128905 3.48E-05 4.458726495 -0.324073463 EVAEAATGEDASSPPPKT(ph)EAASDPQHPAASEGAAAAAASPPLLR ddPTM_HeLa_Curcumin_4h_R1 1 EVAEAATGEDASSPPPKTEAASDPQHPAASEGAAAAAASPPLLR 44 1 Q99536-3;Q99536;K7ERT7 Q99536-3 VAT1 Synaptic vesicle membrane protein VAT-1 homolog 1 0 EVAEAAT(0.001)GEDAS(0.058)S(0.058)PPPKT(0.824)EAAS(0.058)DPQHPAASEGAAAAAASPPLLR 103.92 1.75E-23 25730000 1440.9 1324.5 1254.1 1606.9 2090.5 3434.4 3022.9 1273.9 1649 1561.3 TRUE FALSE FALSE 1326.851245 1438.983878 1300.578049 1600.251074 2065.572153 2722.066726 3107.714438 1662.306246 1468.108826 1615.555059 0.821297447 0.890705563 0.805034803 0.990527104 1.27855262 1.684911146 1.923620258 1.028938158 0.90873339 1 10.6578142 -5.609081656 2.644207744 0.904410453 1.578819562 0.644642901 0.216039206 0.117777077 1.660808553 0.030306806 0.067960307 2.46E-06 5.609081656 0.674409109 EVAENQQNQSSDPEEEKGSQPPPAAES(ph)QSSLRR ddPTM_HeLa_Curcumin_4h_R1 2 EVAENQQNQSSDPEEEKGSQPPPAAESQSSLRR 33 2 O43491;O43491-4;E9PHY5;E9PK52;O43491-3;O43491-2;E9PII3;A0A2R8Y5B3;E9PJP4;E9PQD2;E9PIG0;E9PRG1;E9PQN0 O43491 EPB41L2 Band 4.1-like protein 2 1 0 EVAENQQNQSSDPEEEKGS(0.001)QPPPAAES(0.645)QS(0.177)S(0.177)LRR;EVAENQQNQSSDPEEEKGS(0.005)QPPPAAES(0.332)QS(0.332)S(0.332)LRR ; 82.339 4.05E-08 48720000 4236.6 3169.5 3555.7 3989.8 3795.8 6199.6 6599.4 3862.1 3241 3221.6 TRUE FALSE FALSE 3901.26864 3443.457457 3687.47737 3973.291265 3750.537564 4913.733076 6784.561403 5039.636511 2885.470409 3333.55036 1.170304396 1.032969982 1.10617119 1.191909776 1.125088017 1.474023952 2.035235911 1.511792523 0.865584766 1 11.70284381 -5.098272667 3.056294376 1.090679989 1.775657591 0.781238079 0.150740337 0.071347019 1.269790429 0.018034884 0.054311488 7.97E-06 5.098272667 0.684977602 EVANSTANLVK ddPTM_HeLa_Curcumin_4h_R1 1 EVANSTANLVK 11 0 Q9Y490;Q9Y4G6;H0YMT1;A0A1B0GVU7 Q9Y490;Q9Y4G6 TLN1;TLN2 Talin-1;Talin-2 0 0 127.42 8.15E-08 0 560.01 721.54 660.43 472.26 864.92 896.16 632.91 348.27 708.79 601.68 FALSE FALSE TRUE 515.6846176 783.9067025 684.9061168 470.3059133 854.6063939 710.2863142 650.6677512 454.4559198 631.0375103 622.5883352 0.828291486 1.259109203 1.100094682 0.755404312 1.37266689 1.140860299 1.045101096 0.729946088 1.013571046 1 9.282134737 -7.294376647 24.99092005 0.918915431 1.062449129 0.058259685 0.192706677 1080.257417 819634.9564 0.03249792 0.037163995 5.08E-08 7.294376647 0.143533698 AAS(ph)PYS(ph)QRPASPTAIR ddPTM_HeLa_Curcumin_4h_R1 1 AASPYSQRPASPTAIR 16 1 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 2 0 AAS(0.995)PY(0.005)S(0.683)QRPAS(0.286)PT(0.032)AIR 98.421 0.01325 8476100 2515.2 2511.2 2300.5 2290.3 2465.1 2625.7 1195.4 547.73 2983.3 2012.7 TRUE FALSE FALSE 2316.119266 2728.256938 2385.758554 2280.823345 2435.705293 2081.100222 1228.939707 714.7303556 2656.039454 2082.641175 1.112106729 1.309998559 1.145544697 1.095159057 1.169527099 0.999260097 0.590087107 0.343184589 1.275322646 1 11.02419858 -4.664274778 2.381159986 1.091808719 0.355223877 0.879952689 0.10058154 0.078936323 0.825378436 0.014186681 0.08409418 2.17E-05 4.664274778 -0.736584842 down EVCFACVDGK ddPTM_HeLa_Curcumin_4h_R1 1 EVCFACVDGK 10 0 A0A087WVQ6;Q00610-2;Q00610;J3KS13 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 114.97 0.0038622 2553000 646.16 365.77 352.79 649.76 440.42 318.87 590.85 425.55 559.76 483.01 FALSE FALSE TRUE 595.0157542 397.385529 365.8647077 647.0714653 435.1682791 252.7327676 607.4276608 555.298236 498.3557285 499.7945615 1.190520666 0.795097745 0.73203019 1.294674883 0.870694306 0.505673305 1.215354683 1.111052978 0.997121151 1 8.965191393 -7.269170683 24.92342426 1.089968089 0.930467755 0.061027997 0.226929453 1048.738205 3380813.51 0.039015151 0.045049376 5.38E-08 7.269170683 -0.159500335 EVDAT(ph)SPAPSTSSTVK ddPTM_HeLa_Curcumin_4h_R1 1 EVDATSPAPSTSSTVK 16 0 X6RHM1;Q16666-3;Q16666-2;Q16666;H3BM18;Q16666-6 X6RHM1 IFI16 Gamma-interferon-inducible protein 16 1 0 EVDAT(0.744)S(0.256)PAPSTSSTVK 264.92 2.61E-51 56362000 5060 3328.1 4501.3 5027.5 5134.9 6311.8 5038.9 2406.4 5225.8 3852.6 TRUE FALSE FALSE 4659.495661 3615.766134 4668.122138 5006.697537 5073.669671 5002.661531 5180.277972 3140.100282 4652.542814 3986.477563 1.168825257 0.907007772 1.170989191 1.25592016 1.272719987 1.254907735 1.299462468 0.787687936 1.167081149 1 11.96089883 -6.549525573 24.99265154 1.067568435 1.193304788 0.106247308 0.155021872 330.3750588 309864.7329 0.023603072 0.033380276 2.82E-07 6.549525573 0.125736353 EVDATS(ph)PAPSTSSTVK ddPTM_HeLa_Curcumin_4h_R1 3 EVDATSPAPSTSSTVK 16 0 X6RHM1;Q16666-3;Q16666-2;Q16666;H3BM18;Q16666-6 X6RHM1 IFI16 Gamma-interferon-inducible protein 16 1 0 EVDAT(0.003)S(0.997)PAPSTSSTVK;EVDAT(0.003)S(0.997)PAPSTSSTVK;EVDAT(0.018)S(0.982)PAPSTSSTVK ;; 225.6 1.18E-21 239613000 17691.8 12780 15599.6 16966.3 18084.6 23521.9 19281.6 9230.9 18437 14259.6 TRUE FALSE FALSE 16291.47536 13884.64625 16177.7349 16896.09795 17868.95296 18643.19279 19822.5898 12045.35892 16414.50723 14755.12004 1.104123539 0.941005306 1.096414997 1.145100677 1.211034062 1.263506684 1.343438057 0.81635113 1.112461788 1 13.84892804 -6.32084215 2.964719339 1.041943324 1.177617066 0.127128199 0.13736353 0.341607352 5.938778598 0.020203598 0.032792157 4.78E-07 6.32084215 0.135673742 EVDDLEQWIAER ddPTM_HeLa_Curcumin_4h_R1 3 EVDDLEQWIAER 12 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 ;; ;; 226.33 6.76E-18 38080200 5687.88 4671.76 4833.2 4817.32 4975.58 6403.1 4420.74 4668.13 5808.83 4673.36 FALSE FALSE TRUE 5237.678296 5075.566117 5012.322644 4797.387206 4916.249458 5075.024882 4544.774067 6091.421348 5171.615882 4835.758912 1.083114024 1.049590397 1.036512104 0.992065008 1.016644863 1.049478474 0.939826437 1.259661918 1.069452794 1 12.23952661 -1.87905024 0.005306515 2.37E-08 2.156790606 0.034908475 0.079032915 104921.3272 50.33267404 9562.461441 10937.96181 0.013211428 1.87905024 2.156790582 EVDDLGPEVGDIK ddPTM_HeLa_Curcumin_4h_R1 1 EVDDLGPEVGDIK 13 0 O43143 O43143 DHX15 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 0 0 134.98 0.01124 6096500 2407.6 1987.1 2112.2 2216.6 2459.4 3169.7 1946.6 2335.3 2668.6 2365.9 FALSE FALSE TRUE 2217.03592 2158.85607 2190.47999 2207.428297 2430.073261 2512.26849 2001.216357 3047.32222 2375.861257 2448.114849 0.905609441 0.881844277 0.894761939 0.901684942 0.992630416 1.026205323 0.817451991 1.24476277 0.970486028 1 11.25745553 -4.246017225 24.74220502 0.942363893 1.244763025 0.694754828 0.061811095 1187.427264 1904989.104 0.008898346 0.288076704 5.68E-05 4.246017225 0.302399132 EVDEDS(ph)EPER ddPTM_HeLa_Curcumin_4h_R1 1 EVDEDSEPER 10 0 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 0 EVDEDS(1)EPER 114.71 0.0055788 24361000 803.37 767.17 1072.2 1053 812.08 1253.2 1026.2 547.71 750.93 963.4 TRUE FALSE FALSE 739.7824168 833.4807564 1111.936675 1048.642965 802.3964764 993.2721935 1054.99241 714.7042577 668.5548577 996.8780783 0.742099192 0.836090967 1.115418926 1.051926999 0.80490934 0.996382823 1.058296328 0.716942496 0.67064857 1 9.961273258 EVDEDS(ph)EPEREVR ddPTM_HeLa_Curcumin_4h_R1 3 EVDEDSEPEREVR 13 1 F8WC91;B9A018;Q53GS9-3;Q53GS9 F8WC91 USP39 U4/U6.U5 tri-snRNP-associated protein 2 1 0 EVDEDS(1)EPEREVR;EVDEDS(1)EPEREVR;EVDEDS(1)EPEREVR ;; 174.95 0.0019241 165545000 7802.4 6237.9 6201.4 7804.5 6523.4 8326.8 6738.2 4718 7761.6 7810.5 TRUE FALSE FALSE 7184.831807 6777.07628 6431.229339 7772.207047 6445.612716 6599.727818 6927.255757 6156.496481 6910.171899 8081.914294 0.889001237 0.838548398 0.795755697 0.961678974 0.797535396 0.816604529 0.857130564 0.761762159 0.855016726 1 12.98048134 -13.52287859 0.108794262 1.570453353 0.736014763 0.098062574 0.067664786 46.1309008 0.369423397 5.778327596 0.308014912 3.00E-14 13.52287859 -0.83443859 EVDEQMLNVQNK ddPTM_HeLa_Curcumin_4h_R1 5 EVDEQMLNVQNK 12 0 Q5JP53;P07437;Q5ST81;P68371;Q9BVA1;Q13885 Q5JP53;P68371;Q9BVA1 TUBB;TUBB4B;TUBB2B;TUBB2A Tubulin beta chain;Tubulin beta-4B chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 0 ;;;; ;;;; 305.7 9.94E-134 50901900 17812.4 13862.39 16484.85 15206.36 16672.31 17920.57 14607.67 15356.47 17298.35 14528.63 FALSE FALSE TRUE 16402.52974 15060.59322 17095.79304 15143.44011 16473.50359 14203.64178 15017.52191 20038.58701 15400.76428 15033.49881 1.091065357 1.001802269 1.137179924 1.007313088 1.095786403 0.944799474 0.998937246 1.332929032 1.024429807 1 13.87589319 -1.001631499 0.012425351 0.283351828 1.9817327 0.109735771 0.099230167 15548.14068 15.08030872 858.3440129 1235.472477 0.099625038 1.001631499 1.698380871 EVDGLLTSEPMGS(ph)PVSSK ddPTM_HeLa_Curcumin_4h_R1 5 EVDGLLTSEPMGSPVSSK 18 0 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3;H3BUF6 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 0 EVDGLLTSEPMGS(0.998)PVS(0.001)SK;EVDGLLTSEPMGS(0.999)PVSSK;EVDGLLTS(0.001)EPMGS(0.915)PVS(0.078)S(0.005)K;EVDGLLTSEPMGS(0.955)PVS(0.044)S(0.001)K;EVDGLLTSEPMGS(1)PVSSK ;;;; 200.33 3.29E-10 1009976000 31347 27452.9 29320.6 28805 31352.3 35978.6 29361.5 25107.4 30545.3 25843.1 TRUE FALSE FALSE 28865.85187 29825.80635 30407.24723 28685.81254 30978.4443 28516.2328 30185.30467 32762.53068 27194.55701 26741.1458 1.079454564 1.115352594 1.137095899 1.072721893 1.158456131 1.066380364 1.128796234 1.225173032 1.016955564 1 14.70677366 -13.52287874 0.04927121 0.434400706 1.404894849 0.640115812 0.038280843 188.9816262 0.738133843 14.30173993 3.60088948 3.00E-14 13.52287874 0.970494143 EVDPLVYNMSHEDPGNVS(ph)YSEIGGLSEQIR ddPTM_HeLa_Curcumin_4h_R1 1 EVDPLVYNMSHEDPGNVSYSEIGGLSEQIR 30 0 A0A087X2I1;P62333;H0YJS8;H0YJC0 A0A087X2I1 PSMC6 26S protease regulatory subunit 10B 1 0 EVDPLVY(0.002)NMS(0.005)HEDPGNVS(0.924)Y(0.01)S(0.058)EIGGLS(0.001)EQIR 65.663 0.0002149 4992900 1439.9 998.7 1119.4 1186.5 1287.7 1736.9 1282.8 1248.6 1501.2 1362 TRUE FALSE FALSE 1325.930396 1085.023178 1160.885949 1181.590577 1272.345019 1376.647361 1318.791916 1629.292392 1336.522116 1409.329399 0.940823626 0.769886145 0.82371513 0.838406251 0.90280173 0.976810221 0.935758466 1.156076354 0.948339059 1 10.46079313 -4.26056734 6.635470538 0.933005237 1.160251374 0.473786076 0.074241676 0.103007785 28.74885342 0.012362245 0.103847782 5.49E-05 4.26056734 0.227246137 EVDSKPVSQK(ac)PPPPSEK ddPTM_HeLa_Curcumin_4h_R1 1 EVDSKPVSQKPPPPSEK 17 2 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 0 1 EVDSKPVSQK(1)PPPPSEK 153.92 3.09E-24 0 2518 2852.4 2290.5 2631 3061.1 3480 3332.9 3615.9 2988.8 2433.2 FALSE TRUE FALSE 2318.697643 3098.948746 2375.387945 2620.113619 3024.598382 2758.208772 3426.412204 4718.371264 2660.936118 2517.753519 0.920939093 1.23083881 0.943455317 1.04065533 1.201308372 1.095503889 1.360900572 1.874040183 1.056869188 1 11.29792134 -1.000000019 0.627085601 0.983287549 68.64586449 0.86660221 0.097598799 39.80770673 0.258582252 0.016343808 3727.777056 0.099999996 1.000000019 67.66257694 EVDVNLPK ddPTM_HeLa_Curcumin_4h_R1 2 EVDVNLPK 8 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 103.56 0.010159 6191600 7149.9 6214.6 6020.3 6417.5 6147.9 7363 5807.6 5762 7915.2 6350.7 FALSE FALSE TRUE 6583.97787 6751.762332 6243.417614 6390.946085 6074.590308 5835.830802 5970.545626 7518.807275 7046.922363 6571.386352 1.001916113 1.027448695 0.950091393 0.972541522 0.924400116 0.888066915 0.908567128 1.144173675 1.07236464 1 12.68198205 -6.7473911 24.86226676 1.002920903 0.957140808 0.117401675 0.069931622 391.4343805 692748.1892 0.009941021 0.01401929 1.79E-07 6.7473911 -0.045780095 EVDYSDS(ph)LTEK ddPTM_HeLa_Curcumin_4h_R1 1 EVDYSDSLTEK 11 0 P51532;P51532-4;P51532-3;P51532-2;P51532-5;A0A0A0MT49;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8Y440;A0A2R8Y4C5;A0A2R8Y6N0;A0A2R8YG32;A0A2R8Y7F3;A0A2R8YF80;A0A2R8YF58;A0A2R8Y526;A0A2R8Y7Y7;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;K7EP28 P51532 SMARCA4 Transcription activator BRG1 1 0 EVDYS(0.029)DS(0.941)LT(0.03)EK 278.38 7.48E-56 56387000 4101.3 2992.6 3484.9 4156.4 4068.3 5819.4 4979.3 1803.2 3498.4 3677.2 TRUE FALSE FALSE 3776.677777 3251.267009 3614.05346 4139.201918 4019.78818 4612.390842 5119.005757 2352.987379 3114.634273 3804.982426 0.992561162 0.854476222 0.949821328 1.087837329 1.05645381 1.212197673 1.345342812 0.618396385 0.818567321 1 11.89367408 -6.250261427 22.44493691 0.980306133 1.087482158 0.081038672 0.186147897 377.0303392 757058.7886 0.025028823 0.041190155 5.62E-07 6.250261427 0.107176026 EVDYSDSLT(ph)EK ddPTM_HeLa_Curcumin_4h_R1 1 EVDYSDSLTEK 11 0 P51532;P51532-4;P51532-3;P51532-2;P51532-5;A0A0A0MT49;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8Y440;A0A2R8Y4C5;A0A2R8Y6N0;A0A2R8YG32;A0A2R8Y7F3;A0A2R8YF80;A0A2R8YF58;A0A2R8Y526;A0A2R8Y7Y7;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;K7EP28 P51532 SMARCA4 Transcription activator BRG1 1 0 EVDYS(0.007)DS(0.142)LT(0.852)EK 187.62 0.00016886 49996000 2447.6 2278.5 2646.4 2900.8 2980.3 3967.6 3725.3 1415.8 2541.5 2784.9 TRUE FALSE FALSE 2253.869877 2475.443387 2744.477912 2888.797258 2944.761869 3144.675036 3829.821892 1847.470902 2262.703809 2881.675068 0.782138799 0.859029325 0.95238979 1.002471545 1.021892406 1.091266351 1.329026279 0.641110069 0.785204353 1 11.49269195 -6.275691001 2.045177338 0.891981636 1.045756921 0.147523423 0.168471247 0.480374479 3.920894741 0.02630622 0.045562005 5.30E-07 6.275691001 0.153775284 EVEDKES(ph)EGEEEDEDEDLSK ddPTM_HeLa_Curcumin_4h_R1 14 EVEDKESEGEEEDEDEDLSK 20 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(0.936)EGEEEDEDEDLS(0.064)K;EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(0.999)EGEEEDEDEDLS(0.001)K;EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(1)EGEEEDEDEDLSK;EVEDKES(1)EGEEEDEDEDLSK ;;;;;;;;;;;;; 112.82 8.41E-05 7091436800 42237.18 44353.36 41900.59 43229.89 43831.33 44467.9 40360.82 43154.22 42840.84 39112.28 TRUE FALSE FALSE 38894.06263 48187.0668 43453.46272 43051.01617 43308.67002 35244.75628 41493.23598 56311.74302 38141.30703 40471.42882 0.961025192 1.190644072 1.073682447 1.06373848 1.070104794 0.870855251 1.025247618 1.391394983 0.942425512 1 15.30461616 -4.264321594 5.775251662 1.007066932 1.40273012 0.632855282 0.083824856 0.063690945 9.241470412 0.011728615 0.098965548 5.44E-05 4.264321594 0.395663188 EVEDKES(ph)EGEEEDEDEDLSKYK ddPTM_HeLa_Curcumin_4h_R1 1 EVEDKESEGEEEDEDEDLSKYK 22 2 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 EVEDKES(1)EGEEEDEDEDLSKYK 89.557 0.00026765 28970000 1947.3 1366.7 1553.4 1817.5 1359.9 1901.3 1470.6 1456.4 1428.5 1584.7 TRUE FALSE FALSE 1793.16915 1484.831458 1610.970371 1809.979667 1343.684081 1506.948948 1511.861078 1900.449656 1271.797124 1639.768207 1.093550383 0.905513018 0.982437861 1.103802146 0.819435378 0.919001199 0.921996823 1.158974572 0.775595672 1 10.67927618 -7.267806268 24.73822148 1.044176568 0.968467554 0 0.127321995 701.5643102 2725888.888 0.01613317 0.018682618 5.40E-08 7.267806268 -0.075709014 EVEEDEYK ddPTM_HeLa_Curcumin_4h_R1 1 EVEEDEYK 8 0 P14625 P14625 HSP90B1 Endoplasmin 0 0 152.59 6.25E-15 0 2949.8 2388.3 2723.4 2533.4 2099.5 3338.1 2882.2 1413.7 2539.8 2065.6 FALSE FALSE TRUE 2716.320217 2594.73401 2824.3316 2522.917462 2074.464834 2645.740432 2963.066775 1844.730622 2261.190294 2137.379446 1.27086476 1.213979116 1.321399251 1.180378836 0.970564603 1.237843115 1.386308257 0.863080547 1.057926471 1 11.06162734 -9.449329827 1.190173344 1.000307335 1.196004282 0.13165342 0.149693998 0.609714506 1.548616064 0.097143192 0.024309018 3.55E-10 9.449329827 0.195696947 EVEEELATSGGQS(ph)PTGEQIPQFQQR ddPTM_HeLa_Curcumin_4h_R1 1 EVEEELATSGGQSPTGEQIPQFQQR 25 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 1 0 EVEEELAT(0.001)S(0.041)GGQS(0.922)PT(0.035)GEQIPQFQQR 116.72 1.01E-08 8755400 1236.7 745.68 1116.9 810.89 1032.3 1113.2 1437.5 1516.6 1203.6 1180.8 TRUE FALSE FALSE 1138.81389 810.1332565 1158.293297 807.534752 1019.990497 882.3097717 1477.832381 1979.004358 1071.568091 1221.832712 0.932053855 0.663047607 0.947996632 0.660920881 0.834803723 0.722119946 1.209521047 1.619701567 0.877017026 1 10.25483106 -4.447422274 3.186729347 0.899864912 1.615000237 0.773877304 0.130661233 0.112964871 1.985956547 0.020373035 0.15472267 3.57E-05 4.447422274 0.715135325 EVEELEQLTQQLMQDMEHPQR ddPTM_HeLa_Curcumin_4h_R1 1 EVEELEQLTQQLMQDMEHPQR 21 0 Q15942;Q15942-2;H0Y2Y8;C9JJK5 Q15942 ZYX Zyxin 0 0 83.948 0.00032472 1725600 475.1 506.66 574.94 650.74 710.45 755.01 745.8 617.89 758.28 705.12 FALSE FALSE TRUE 437.4953337 550.4534328 596.2477822 648.0474103 701.9783478 598.4124153 766.7251408 806.2818166 675.0985811 729.6228675 0.599618451 0.754435555 0.817199966 0.888195038 0.962111221 0.820166749 1.050851303 1.105066538 0.92527059 1 9.511007136 -4.393254915 0.74781162 0.807243456 1.267958079 0.391795332 0.111251054 2.250704448 0.994409182 0.026199949 0.832739258 4.04E-05 4.393254915 0.460714622 EVEETDEMDQVELVDFDPNQER ddPTM_HeLa_Curcumin_4h_R1 4 EVEETDEMDQVELVDFDPNQER 22 0 P31689 P31689 DNAJA1 DnaJ homolog subfamily A member 1 0 0 ;;; ;;; 169.77 8.14E-09 27261300 10722.2 8658.8 8803.1 8946 9619.1 12148.8 8949.6 8269.87 10575.9 9313.9 FALSE FALSE TRUE 9873.526556 9407.228089 9129.35063 8908.983822 9504.398515 9629.001935 9200.701689 10791.31529 9415.75023 9637.557332 1.024484339 0.976100869 0.947268101 0.92440268 0.986183344 0.999112286 0.954671539 1.11971477 0.976985133 1 13.23445182 -7.252750537 23.99723122 1.011562049 0.982076873 0 0.051060961 780.7815903 2156398.036 0.008009343 0.009735434 5.59E-08 7.252750537 -0.029485176 EVEKVK(ac)LDQK ddPTM_HeLa_Curcumin_4h_R1 2 EVEKVKLDQK 10 2 M0QXN5;P37198 M0QXN5 NUP62 Nuclear pore glycoprotein p62 0 1 ; EVEK(0.223)VK(0.777)LDQK;EVEK(0.227)VK(0.773)LDQK 93.598 0.0014501 0 2285.98 1750.72 2093.76 2337.25 1995.14 3031.6 2685.85 1780.44 2052.68 2013.86 FALSE TRUE FALSE 2105.042271 1902.044436 2171.356587 2327.579079 1971.349259 2402.811987 2761.207722 2323.28796 1827.50614 2083.841485 1.010173896 0.912758696 1.041997006 1.116965516 0.946016898 1.153068505 1.325056508 1.114906281 0.876989038 1 11.02502982 -5.084412261 4.802654494 1.006337221 1.224754068 0.589095874 0.080754688 0.090183271 3.596350383 0.008983615 0.02421828 8.23E-06 5.084412261 0.218416847 EVELVS(ph)E ddPTM_HeLa_Curcumin_4h_R1 1 EVELVSE 7 0 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 0 EVELVS(1)E 90.37 0.015363 932040000 6538.5 7766.5 7763.9 7773.2 6046.6 6210.9 5500.8 5199.5 7779.3 7716.7 TRUE FALSE FALSE 6020.970826 8437.801653 8051.636964 7741.036558 5974.498244 4922.689329 5655.137643 6784.803614 6925.930253 7984.854751 0.754048886 1.056725754 1.00836361 0.969464918 0.748228794 0.616503303 0.708233001 0.849709084 0.867383374 1 12.96305045 -5.67356228 6.056189691 0.911113953 0.717497688 0.51298496 0.098310411 0.180789169 10.0394683 0.017972639 0.036151679 2.12E-06 5.67356228 -0.193616265 EVESPYEVHDYIR ddPTM_HeLa_Curcumin_4h_R1 2 EVESPYEVHDYIR 13 0 Q6Y7W6-4;Q6Y7W6-5;Q6Y7W6;I1E4Y6;Q6Y7W6-3 Q6Y7W6-4 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 0 0 ; ; 141.73 0.00073227 11218500 7810.4 6741.6 7412.7 6460.7 8253.5 9610 6959.4 5474.8 8366.8 7100 FALSE FALSE TRUE 7192.198599 7324.313864 7687.421183 6433.967335 8155.082403 7616.777673 7154.662034 7144.041317 7448.982973 7346.724472 0.978966698 0.996949578 1.046373961 0.875759988 1.110029706 1.036758314 0.973857406 0.972411766 1.013918924 1 12.84288545 -5.73143098 24.99985383 0.987957684 1.020698951 0.102202734 0.054539148 428.2816249 356797.316 0.007407351 0.01481319 1.86E-06 5.73143098 0.032741267 EVESRLS(ph)PGESAYQK ddPTM_HeLa_Curcumin_4h_R1 1 EVESRLSPGESAYQK 15 1 A0A0G2JHC2;Q6NYC8;Q6NYC8-2 A0A0G2JHC2 PPP1R18 Phostensin 1 0 EVESRLS(1)PGESAYQK 156.17 0.0035012 24966000 1891.4 1249.1 1276.2 1734.5 1304 1720.7 1393.8 2288.6 1842.4 1612.9 TRUE FALSE FALSE 1741.693694 1357.066638 1323.497095 1727.323099 1288.450652 1363.807424 1432.906277 2986.383605 1640.293329 1668.948155 1.043587657 0.813126899 0.793012707 1.034977086 0.772013587 0.817165842 0.858568478 1.789380692 0.982830608 1 10.70472342 -4.257416644 24.97596742 0.954691125 1.789381021 0.845577947 0.111757497 134.7749707 836744.0337 0.017997606 0.183797805 5.53E-05 4.257416644 0.834689896 EVEVEVESMDK ddPTM_HeLa_Curcumin_4h_R1 1 EVEVEVESMDK 11 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 0 155.11 0.0037544 8140800 1320.9 1272.8 1327.4 1332.5 1415.3 1574.5 1306.2 1279.9 1912.1 1273.7 FALSE FALSE TRUE 1216.349371 1382.815161 1376.594612 1326.986468 1398.423472 1247.930952 1342.848457 1670.135618 1702.347414 1317.96098 0.922902415 1.049207967 1.044488139 1.006848069 1.061050739 0.94686487 1.018883318 1.267211733 1.291652363 1 10.36409194 -4.267921644 3.729766244 0.9838096 1.295343269 0.161311412 0.107058647 0.103210989 2.703290446 0.007342915 0.087626536 5.40E-05 4.267921644 0.311533669 EVFEDAAEIR ddPTM_HeLa_Curcumin_4h_R1 5 EVFEDAAEIR 10 0 P19338;H7BY16 P19338 NCL Nucleolin 0 0 ;;;; ;;;; 166.07 6.87E-09 300917200 25590.3 22208.3 22347.9 23885 23033.5 29350.6 24805.1 23154.2 25279.9 22144 FALSE FALSE TRUE 23564.80075 24127.88649 23176.13283 23786.1702 22758.84056 23262.95471 25501.06435 30213.80899 22506.75822 22913.50235 1.028424219 1.052998626 1.011461822 1.03808531 0.99325019 1.015250936 1.112927389 1.318602828 0.982248714 1 14.48391037 -4.300727857 2.099558468 1.016572255 1.387445443 0.953209438 0.020457569 0.084018293 0.432320801 0.002725614 0.056870154 5.00E-05 4.300727857 0.370873188 EVFEFRPELVNDDDEEADDTR ddPTM_HeLa_Curcumin_4h_R1 3 EVFEFRPELVNDDDEEADDTR 21 1 Q8WU90;Q8WU90-2 Q8WU90 ZC3H15 Zinc finger CCCH domain-containing protein 15 0 0 ;; ;; 251.74 1.17E-47 71823000 6642.7 6619.8 7396.8 7461.4 7078.8 7877.3 6633.9 5535.9 7494.3 5911.3 FALSE FALSE TRUE 6116.923286 7191.986015 7670.931915 7430.526704 6994.389933 6243.459185 6820.02938 7223.770426 6672.19404 6116.717235 1.000033686 1.175791808 1.254092942 1.214789963 1.143487538 1.020720583 1.114981961 1.180988126 1.090812896 1 12.57854187 -7.265881577 24.60035969 1.000015903 1.156255069 0.425069278 0.065170671 162.2269071 898391.4521 0.010925718 0.012730998 5.42E-08 7.265881577 0.156239166 EVFLVMPTGGGK ddPTM_HeLa_Curcumin_4h_R1 1 EVFLVMPTGGGK 12 0 P46063;F5H2L2;F8WA66;F8WD97 P46063 RECQL ATP-dependent DNA helicase Q1 0 0 129.89 2.04E-10 0 572.35 418.66 465.02 487 621.31 748.69 400.21 409.98 716.19 503.56 FALSE FALSE TRUE 527.0478936 454.8471049 482.2540503 484.984923 613.901284 593.4032545 411.4388155 534.9810147 637.6257488 521.0586725 1.011494331 0.872928768 0.925527346 0.930768354 1.178180724 1.138841527 0.789620895 1.026719337 1.223711997 1 9.025302023 EVFSSCSSEVVLS(ph)GDDEEYQR ddPTM_HeLa_Curcumin_4h_R1 1 EVFSSCSSEVVLSGDDEEYQR 21 0 Q09666;E9PKR9;E9PLK4 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 EVFSSCS(0.004)S(0.026)EVVLS(0.97)GDDEEYQR 93.166 0.00017941 7736600 1363.3 1138.7 1081.3 1212.2 963.84 1270.4 1108 920.57 1495.2 1264.5 TRUE FALSE FALSE 1255.393366 1237.124154 1121.373929 1207.184238 952.3468375 1006.90472 1139.087498 1201.247555 1331.180301 1308.441281 0.959457168 0.945494591 0.857030381 0.922612467 0.727848358 0.76954521 0.870568297 0.918075249 1.017378709 1 10.35363347 -6.769303127 1.106764486 0.98459532 0.828641808 0.588900407 0.057194992 0.243444679 0.595158388 0.010989176 0.016739444 1.70E-07 6.769303127 -0.155953512 EVGEHVVSVR ddPTM_HeLa_Curcumin_4h_R1 1 EVGEHVVSVR 10 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 0 0 72.096 0.019926 2207700 1031.2 861.07 680.66 739.82 990.99 1120.7 775.61 898.98 1073.1 897.09 FALSE FALSE TRUE 949.5794319 935.4970539 705.8858584 736.7588209 979.1730915 888.2541871 797.3715292 1173.074864 955.3836148 928.2638107 1.022962891 1.007792228 0.760436689 0.793695512 1.054843548 0.956898434 0.858992368 1.263730041 1.029215621 1 9.858391064 -4.247035538 24.44951435 0.971416248 1.263730317 0.450584185 0.102002511 1515.991094 2573231.972 0.01492762 0.419468138 5.66E-05 4.247035538 0.292314069 EVGLLKDMS(ph)PLSETEMALGK ddPTM_HeLa_Curcumin_4h_R1 1 EVGLLKDMSPLSETEMALGK 20 1 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 EVGLLKDMS(0.995)PLS(0.005)ET(0.001)EMALGK 69.148 0.0048448 0 1623.5 1072.6 1030.6 1696.4 953.48 1629.5 1544.5 2435.6 1914.4 1581.5 TRUE FALSE FALSE 1494.998262 1165.310765 1068.794943 1689.380746 942.1103737 1291.523332 1587.834513 3178.203228 1704.39511 1636.457007 0.913557921 0.712093724 0.653115198 1.03234044 0.575701268 0.789219225 0.970287949 1.942124488 1.04151536 1 10.67635999 -4.263461217 4.38309656 0.887228261 2.015705757 0.809110274 0.158297895 0.068439607 3.166434955 0.02287449 0.238422458 5.45E-05 4.263461217 1.128477496 EVGS(ph)PPLDPTER ddPTM_HeLa_Curcumin_4h_R1 2 EVGSPPLDPTER 12 0 A0A1B0GV79;A0A1B0GW21;A0A1B0GTE6;A0A0D9SFK7;A0A1B0GUH6;A0A1B0GUA3;Q96EK5 A0A1B0GV79 KIF1BP;KIAA1279 KIF1-binding protein 1 0 EVGS(0.999)PPLDPT(0.001)ER;EVGS(1)PPLDPTER ; 126.83 0.0028668 11592200 4763.8 4105.1 4139.6 4785.3 4418.1 5018 4238.8 8067.7 4555.7 4174.4 TRUE FALSE FALSE 4386.740203 4459.926552 4293.017218 4765.499697 4365.417043 3977.210235 4357.72932 10527.50459 4055.951108 4319.460089 1.015576047 1.032519449 0.9938782 1.103262815 1.010639513 0.920765594 1.008859725 2.437226962 0.938994926 1 12.07663528 -4.261431401 24.98283502 1.009186825 2.437227363 0.987993645 0.047435969 0.039872174 122570.8398 0.005645884 0.043420415 5.48E-05 4.261431401 1.428040537 EVGSIIGK ddPTM_HeLa_Curcumin_4h_R1 2 EVGSIIGK 8 0 Q15365;H3BSP4;C9K0A2;F8WC71;F8VTZ0;C9IZV9;C9J7A9;C9JSA6;C9J5V4;C9JTY5;C9JZY3;C9J0A4;P57723-2;P57723;Q15366;Q15366-2;Q15366-3;Q15366-6;Q15366-5;H3BRU6;F8VZX2;Q15366-8;Q15366-4;P57721;E9PFP8;J3QT27;F8W0G4;P57721-4;P57721-5;P57721-3;P57721-2;Q15366-7;F8W1G6 Q15365;Q15366 PCBP1;PCBP2;PCBP4;PCBP3 Poly(rC)-binding protein 1;Poly(rC)-binding protein 4;Poly(rC)-binding protein 2;Poly(rC)-binding protein 3 0 0 ; ; 159.04 5.16E-06 23952000 11411.6 9690.9 10055 10649.9 10775.5 12338.2 9325.3 8193.2 12202.1 10136.2 FALSE FALSE TRUE 10508.35982 10528.53821 10427.64715 10605.83354 10647.0092 9779.11824 9586.94282 10691.26896 10863.56016 10488.4322 1.001899962 1.003823834 0.994204563 1.011193412 1.015119229 0.932371784 0.914049177 1.019339093 1.035765876 1 13.35651142 -5.2654555 24.99930897 1.002239313 0.951132933 0.420550207 0.027967057 214.8476666 1337374.913 0.003338172 0.007756684 5.43E-06 5.2654555 -0.051106379 EVGVYEALKDDSWLK ddPTM_HeLa_Curcumin_4h_R1 2 EVGVYEALKDDSWLK 15 1 B8ZZ51;B9A041;A0A5K1VW95;P40925-2;P40925;P40925-3 B8ZZ51 MDH1 "Malate dehydrogenase, cytoplasmic" 0 0 ; ; 145.61 0.00041923 37485000 4525.8 3712 4167.4 4502.1 4702 5240.4 4413.7 3741.6 3832.6 4052.2 FALSE FALSE TRUE 4167.578154 4032.84874 4321.84751 4483.471503 4645.931721 4153.481969 4537.536543 4882.396616 3412.173369 4193.013648 0.993933839 0.961801959 1.030725839 1.06927186 1.108017314 0.990572013 1.082165937 1.164412288 0.813775879 1 12.03377181 -6.40166369 3.02369745 0.994424182 1.07956 0.397639777 0.070643272 0.169509056 2.965411228 0.006380905 0.010053978 3.97E-07 6.40166369 0.085135818 EVIEIEDAS(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 2 EVIEIEDASPTK 12 0 P46100-5;P46100-3;P46100-4;P46100;P46100-2 P46100-5 ATRX Transcriptional regulator ATRX 1 0 EVIEIEDAS(0.978)PT(0.022)K;EVIEIEDAS(0.983)PT(0.017)K ; 192.4 4.57E-06 26071000 8865.3 7799.4 9318.6 8578.7 10011.2 9410.2 7910.9 4209.1 7672.9 7002.7 TRUE FALSE FALSE 8163.60215 8473.545383 9663.955513 8543.203612 9891.822979 7458.418445 8132.858563 5492.435214 6831.202067 7246.043304 1.126628949 1.169403083 1.333687243 1.179016362 1.3651344 1.029309118 1.122386138 0.757990945 0.942749274 1 12.82297771 -2.790692406 8.833149945 1.099200961 0.720094648 0 0.17144101 0 0 0.02195144 0 0.001619226 2.790692406 -0.379106313 EVIEIEDAS(ph)PTKCPITTK ddPTM_HeLa_Curcumin_4h_R1 1 EVIEIEDASPTKCPITTK 18 1 P46100-5;P46100-3;P46100-4;P46100;P46100-2 P46100-5 ATRX Transcriptional regulator ATRX 1 0 EVIEIEDAS(0.854)PT(0.14)KCPIT(0.005)T(0.001)K 71.535 0.0056778 6392200 1608 1243.3 1465 1322.4 1580.5 1689.5 992.71 599.72 1630.3 1389.8 TRUE FALSE FALSE 1480.725103 1350.765312 1519.294189 1316.928259 1561.65357 1339.078655 1020.562771 782.5718672 1451.460169 1438.095447 1.029643134 0.939273756 1.056462693 0.915744683 1.085917888 0.931147274 0.709662751 0.544172412 1.009293349 1 10.48994372 -4.651553902 2.124290662 1.00905286 0.543867992 0.908918159 0.048523049 0.064600892 0.514840844 0.006204928 0.042161199 2.23E-05 4.651553902 -0.465184868 EVLDEDT(ph)DEEKETLK ddPTM_HeLa_Curcumin_4h_R1 1 EVLDEDTDEEKETLK 15 1 Q9Y3P9 Q9Y3P9 RABGAP1 Rab GTPase-activating protein 1 1 0 EVLDEDT(1)DEEKETLK 92.633 0.0053111 402900000 5252.3 4114.5 5629.3 4898.2 5251.5 4843.3 4068.8 3654.4 4494.8 4301.2 TRUE FALSE FALSE 4836.574913 4470.139046 5837.92681 4877.932546 5188.879292 3838.744985 4182.959577 4768.609737 4001.731685 4450.66638 1.086708034 1.004375225 1.311697241 1.096000493 1.165865704 0.862510163 0.939850175 1.071437248 0.899130904 1 12.11980565 -5.261146666 24.99999981 1.071281414 0.956124298 0.193402938 0.113628249 33.36749868 2849692.153 0.014947231 0.035656383 5.48E-06 5.261146666 -0.115157116 EVLPALENNKEQIQK ddPTM_HeLa_Curcumin_4h_R1 1 EVLPALENNKEQIQK 15 1 Q9UHV9 Q9UHV9 PFDN2 Prefoldin subunit 2 0 0 73.156 0.010079 0 387.9 329.49 324.91 415.78 349.88 367.43 222.04 289.52 460.67 369.7 FALSE FALSE TRUE 357.1973057 357.9696474 336.9514504 414.0596125 345.7079095 291.2208762 228.2698448 377.7933152 410.1356535 382.5470475 0.933734316 0.935753262 0.880810485 1.082375659 0.903700373 0.761268132 0.596710513 0.98757347 1.072118204 1 8.579493378 -5.371267898 4.034419317 0.965740797 0.763664962 0.407038166 0.1067585 0.150132133 4.23792244 0.013386545 0.031401874 4.25E-06 5.371267898 -0.202075835 EVLT(ph)PTSTSDNETR ddPTM_HeLa_Curcumin_4h_R1 2 EVLTPTSTSDNETR 14 0 H7C150;H7C183;Q70CQ2-3;Q70CQ2-2;Q70CQ2 H7C150 USP34 Ubiquitin carboxyl-terminal hydrolase 34 1 0 EVLT(0.995)PT(0.003)S(0.001)TSDNETR;EVLT(0.974)PT(0.009)S(0.015)T(0.002)SDNETR ; 137.46 0.0024584 16001500 3636.7 2925.8 3004.2 2588.4 3069.7 3549.5 1959.98 1924.48 3702 3063.4 TRUE FALSE FALSE 3348.851358 3178.693115 3115.538295 2577.689887 3033.095832 2813.293689 2014.971764 2511.245093 3295.899862 3169.852922 1.056469003 1.002788834 0.982865253 0.813189113 0.956856961 0.887515528 0.635667273 0.792227638 1.039764287 1 11.63020019 -5.294561266 0.618984072 1.027700581 0.673560928 0.692738236 0.070347361 0.532852931 0.275155429 0.013687228 0.106288982 5.08E-06 5.294561266 -0.354139652 EVMESAVGNSSGSGQNEES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 EVMESAVGNSSGSGQNEESPR 21 0 Q9NVF7 Q9NVF7 FBXO28 F-box only protein 28 1 0 EVMESAVGNS(0.038)S(0.038)GS(0.065)GQNEES(0.859)PR;EVMESAVGNSSGSGQNEES(1)PR;EVMESAVGNSSGSGQNEES(1)PR;EVMESAVGNSSGSGQNEES(1)PR ;;; 212.24 1.89E-18 93703000 11656.8 10288.9 10918.2 10456.5 11622.3 13091.8 9129.5 8058.1 10619.3 9520.6 TRUE FALSE FALSE 10734.15198 11178.22667 11322.8381 10413.23377 11483.71166 10376.41311 9385.649199 10514.9776 9454.389358 9851.440141 1.089602315 1.134679449 1.149358666 1.057026549 1.16568862 1.053288956 0.952718492 1.067354361 0.959696169 1 13.26611893 -3.867211843 19.07349013 1.06018129 3.514053795 0 0.071291465 7108.829931 1197228.375 0.009683071 131757.3981 0.000135765 3.867211843 2.453872505 EVNS(ph)QEEEEEELLRK ddPTM_HeLa_Curcumin_4h_R1 3 EVNSQEEEEEELLRK 15 1 Q96RL1-2;Q96RL1;Q96RL1-3;D6RC40;D6RCQ3;Q96RL1-5 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 0 EVNS(1)QEEEEEELLRK;EVNS(1)QEEEEEELLRK;EVNS(1)QEEEEEELLRK ;; 140.32 0.00025171 65150000 4554.4 3924.9 3771.93 4197.1 4028.6 4445.8 3665.08 3374.77 4385.3 3800.7 TRUE FALSE FALSE 4193.914434 4264.150867 3911.721044 4179.733512 3980.561576 3523.690966 3767.912281 4403.721837 3904.243561 3932.774042 1.066401067 1.084260327 0.994646782 1.062795235 1.012151101 0.895981037 0.958080032 1.119749518 0.992745456 1 11.94133158 -5.518575809 24.84789881 1.035483596 0.982303664 0.085516836 0.059803016 248.2495864 1433551.103 0.008493532 0.017330074 3.03E-06 5.518575809 -0.053179932 EVPAVPETLK ddPTM_HeLa_Curcumin_4h_R1 2 EVPAVPETLK 10 0 P18124 P18124 RPL7 60S ribosomal protein L7 0 0 ; ; 140.83 2.23E-05 10816200 13328.9 11334.2 12329.7 11826.2 13011.2 14383.1 11494.3 10813.9 13000.7 11037.9 FALSE FALSE TRUE 12273.9035 12313.87774 12786.64953 11777.26632 12856.04994 11399.88293 11816.79912 14111.00833 11574.55574 11421.4662 1.074634664 1.078134587 1.119527852 1.031151877 1.125604166 0.998110289 1.03461315 1.235481336 1.013403667 1 13.47946024 -13.52287875 0.168627234 0.659090433 1.105361164 0.229192185 0.061480707 66.31157192 0.732026171 7.405465736 0.09758696 3.00E-14 13.52287875 0.446270731 EVPAVPETLK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EVPAVPETLKK 11 1 P18124 P18124 RPL7 60S ribosomal protein L7 0 1 ; EVPAVPETLK(1)K;EVPAVPETLK(1)K 140.07 2.09E-05 11167200 7000.5 10094.7 7211.1 7023.9 13506.7 17376.3 12985 11449.2 17696.7 7754.4 FALSE TRUE FALSE 6446.403038 10967.24089 7478.34971 6994.836963 13345.64142 13772.25951 13349.32415 14940.00837 15755.41628 8023.864823 0.803403744 1.366827723 0.932013422 0.871754088 1.663243551 1.716412204 1.663702523 1.861946668 1.963569506 1 12.97008159 -5.737061506 7.018928969 0.942935503 1.72514628 0.284743804 0.357070813 0.048468846 8.794442145 0.023718884 0.046770433 1.83E-06 5.737061506 0.782210776 EVPSKEEPS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 2 EVPSKEEPSPVK 12 1 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 EVPS(0.018)KEEPS(0.982)PVK;EVPS(0.001)KEEPS(0.999)PVK ; 65.565 0.018813 50117000 12237 11567.9 12886 12259 15217.5 12835.1 11339.4 10029.4 10860.3 9158.3 TRUE FALSE FALSE 11268.42854 12567.77773 13363.5665 12208.27551 15036.04125 10172.95558 11657.55305 13087.31789 9668.952261 9476.550243 1.189085506 1.326197552 1.410172072 1.288261571 1.586657683 1.07348722 1.230147337 1.381021316 1.02030296 1 13.21014625 -8.003959298 0.843159706 1.031044478 1.32649455 0.486640955 0.126952268 0.324614702 0.499025221 0.039925018 0.029918884 9.91E-09 8.003959298 0.295450072 EVPSKEEPS(ph)PVKAEVAEK ddPTM_HeLa_Curcumin_4h_R1 4 EVPSKEEPSPVKAEVAEK 18 2 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 EVPSKEEPS(1)PVKAEVAEK;EVPS(0.032)KEEPS(0.968)PVKAEVAEK;EVPS(0.062)KEEPS(0.938)PVKAEVAEK;EVPSKEEPS(1)PVKAEVAEK ;;; 95.122 0.0015099 1835835200 21006.1 16816.8 18584.3 19663.6 19406.9 21423.7 17779.8 16098.4 20522.6 17657.5 TRUE FALSE FALSE 19343.44502 18270.36926 19273.05051 19582.23723 19175.48539 16980.18313 18278.65334 21006.72805 18271.32213 18271.09681 1.05869096 0.99996018 1.05483818 1.071760357 1.049498319 0.929346678 1.000413578 1.149724522 1.000012332 1 14.15727562 -4.254516149 24.62645488 1.024654881 1.149724594 0.480723791 0.040499199 480.2531281 1708241.288 0.005885953 0.076895263 5.57E-05 4.254516149 0.125069713 EVPWS(ph)PSAEK ddPTM_HeLa_Curcumin_4h_R1 1 EVPWSPSAEK 10 0 Q5JSZ5;Q5JSZ5-5;Q5JT00 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 EVPWS(0.999)PS(0.001)AEK 166.11 0.00055611 74936000 3590.4 2653.1 3358.7 3229.5 3035.9 3854.9 3163.1 2442.3 3727.3 2968.7 TRUE FALSE FALSE 3306.216051 2882.422142 3483.176377 3216.137185 2999.698875 3055.350286 3251.848073 3186.946027 3318.424515 3071.862104 1.076290517 0.938330577 1.133897375 1.046966653 0.976508311 0.994624818 1.058591813 1.037463896 1.080264804 1 11.58489774 EVQAEQPSSSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 EVQAEQPSSSSPR 13 0 A0A1W2PP04;Q9Y388 A0A1W2PP04 RBMX2 "RNA-binding motif protein, X-linked 2" 1 0 EVQAEQPS(0.001)S(0.004)S(0.176)S(0.818)PR;EVQAEQPSSS(0.008)S(0.992)PR ; 230.57 1.61E-19 30989000 5765.9 4980.8 5524.8 5547.9 6532.8 8140.8 5474.6 4321 7085.4 5054 TRUE FALSE FALSE 5309.522931 5411.318158 5729.553948 5524.94426 6454.900627 6452.306314 5628.202542 5638.453009 6308.149347 5229.626124 1.015277728 1.034742834 1.095595328 1.05647022 1.234294857 1.233798777 1.076215089 1.078175165 1.206233332 1 12.35249209 -6.51573444 1.305179449 1.006881126 1.148955108 0.008795188 0.084197073 0.240694128 0.818949193 0.010062966 0.017009996 3.05E-07 6.51573444 0.142073982 EVQCPEANIDT(ph)ALCKESPGLWGASILK ddPTM_HeLa_Curcumin_4h_R1 1 EVQCPEANIDTALCKESPGLWGASILK 27 1 Q8IVF2;Q8IVF2-3;Q8IVF2-2 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 EVQCPEANIDT(0.819)ALCKES(0.166)PGLWGAS(0.015)ILK 63.085 0.0016553 9391200 446.49 315.2 515.89 472.9 513.18 878.99 727.07 424.03 719.55 253.6 TRUE FALSE FALSE 411.1498454 342.4444835 535.0093372 470.9432651 507.0606637 696.6775657 747.4696274 553.314795 640.6171652 262.4125811 1.56680691 1.304985005 2.038809782 1.794667249 1.932303175 2.654893918 2.848451946 2.10856809 2.441259342 1 8.03569308 -5.956351878 0.303100648 1.012986433 3.006001468 0.154497944 0.509034526 0.955241195 0.149415389 0.17688353 0.67702412 1.11E-06 5.956351878 1.993015035 EVQDKDKPLK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 EVQDKDKPLKK 11 3 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 0 1 EVQDKDK(0.012)PLK(0.987)K 66.595 0.018593 8953600 3085.9 2666.9 3021.1 2496.9 2282.8 3198.1 1317.8 737.03 2637.3 3136.3 FALSE TRUE FALSE 2841.647759 2897.414953 3133.064624 2486.568489 2255.579101 2534.77801 1354.773921 961.7470541 2347.994788 3245.286192 0.875623163 0.892807223 0.965420132 0.766209309 0.695032416 0.781064553 0.417458998 0.296352 0.723509315 1 11.66413 -4.49955708 0.582919614 0.944728444 1.32E-18 0.789380364 0.09903425 0.631224952 0.171579202 0.01423237 0.378714982 3.17E-05 4.49955708 -0.944728444 down EVQDKDYPLT(ph)PPPS(ph)PTVDEPK ddPTM_HeLa_Curcumin_4h_R1 2 EVQDKDYPLTPPPSPTVDEPK 21 1 Q5THJ4-2;Q5THJ4;H3BLS7 Q5THJ4-2 VPS13D Vacuolar protein sorting-associated protein 13D 2 0 EVQDKDYPLT(1)PPPS(0.626)PT(0.374)VDEPK;EVQDKDYPLT(1)PPPS(0.868)PT(0.132)VDEPK ; 107.29 8.66E-05 25824000 7816.8 5869.2 6629.9 7290.9 6456.8 6767.7 5810.5 6290.3 7377.7 6942.1 TRUE FALSE FALSE 7198.092032 6376.507495 6875.609926 7260.732188 6379.806877 5364.002732 5973.526992 8208.183513 6568.384768 7183.337458 1.002054 0.887680348 0.957160925 1.010774202 0.888139658 0.74672849 0.831581006 1.142669902 0.914391786 1 12.81043858 -6.895709137 0.805803741 1.003257697 0.902850258 0 0.105131554 0.856036843 1.118429907 0.022574646 0.033741373 1.27E-07 6.895709137 -0.100407439 EVQQGEEFER ddPTM_HeLa_Curcumin_4h_R1 1 EVQQGEEFER 10 0 P00568;Q5T9B7;H0YID2 P00568 AK1 Adenylate kinase isoenzyme 1 0 0 94.692 0.016245 1413200 291.23 152.36 353.62 316.05 261.31 350.43 206.06 436.32 446.51 454.91 FALSE FALSE TRUE 268.1788382 165.5293195 366.7254683 314.7422688 258.1940489 277.7468678 211.841489 569.3519594 397.5289701 470.7180886 0.569722823 0.351652769 0.779076643 0.668642817 0.548510999 0.590049277 0.450038981 1.209539156 0.844516027 1 8.878719483 -9.239673448 0.992613725 0.998271302 0.628819487 0.181542901 0.224094648 0.525640682 0.936220502 0.134975981 0.03795514 5.76E-10 9.239673448 -0.369451815 EVQQGEEFERR ddPTM_HeLa_Curcumin_4h_R1 1 EVQQGEEFERR 11 1 P00568;Q5T9B7;H0YID2 P00568 AK1 Adenylate kinase isoenzyme 1 0 0 103.14 0.013547 46689000 2306.3 1967.7 2073.5 2043.9 1946.7 2296.3 1798.7 2126.7 2435.7 2284.5 FALSE FALSE TRUE 2123.753921 2137.77922 2150.345734 2035.442883 1923.486874 1820.021495 1849.166681 2775.12104 2168.509804 2363.886205 0.89841631 0.904349463 0.909665503 0.861057897 0.813696899 0.769927711 0.782257063 1.17396558 0.91734949 1 11.20694487 -8.731018802 0.527432508 1.008351133 0.87231527 0.033875763 0.10994863 1.493499344 0.766480396 0.096971476 0.029007383 1.86E-09 8.731018802 -0.136035862 GGQNSTAASTK(ac)YDVFR ddPTM_HeLa_Curcumin_4h_R1 2 GGQNSTAASTKYDVFR 16 1 Q9UMZ2-6;Q9UMZ2-9;Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2 Q9UMZ2-6 SYNRG Synergin gamma 0 1 ; GGQNSTAASTK(1)YDVFR;GGQNSTAASTK(1)YDVFR 344.71 1.43E-203 11992500 1151.31 809.62 1404.57 1051.39 1150.63 1583.84 1623.5 4038.6 1434.5 1095.57 FALSE TRUE FALSE 1060.182599 879.5999452 1456.6246 1047.039627 1136.909489 1255.33373 1669.051041 5269.950549 1277.138939 1133.640976 0.935201374 0.775906979 1.284908212 0.923607781 1.002883199 1.107346821 1.472292442 4.648694481 1.126581489 1 10.1467481 -4.234778926 2.819042977 0.98543935 5.455832864 0.984775639 0.13446004 0.035536533 0.365075577 0.017411861 0.37449701 5.82E-05 4.234778926 4.470393513 up EVQSK(ac)IEK ddPTM_HeLa_Curcumin_4h_R1 1 EVQSKIEK 8 1 Q01995;E9PJ32 Q01995 TAGLN Transgelin 0 1 EVQSK(1)IEK 109.44 0.0066934 12103000 4093.2 3926.8 3391.9 3094 4574.7 5744.1 3219 4461.5 4150.3 3128.9 FALSE TRUE FALSE 3769.218901 4266.215095 3517.606798 3081.197848 4520.14969 4552.708911 3309.316477 5821.790812 3695.022474 3237.629042 1.164191095 1.317697315 1.086476169 0.95168341 1.396129585 1.406186086 1.022141954 1.798164872 1.141274193 1 11.66072198 -1 0.649802707 1.101527243 51.66182271 0.476199097 0.176611201 131.1470356 0.785416954 0.029886325 9558.274389 0.1 1 50.56029546 EVQTNDLKEVVNK ddPTM_HeLa_Curcumin_4h_R1 1 EVQTNDLKEVVNK 13 1 P61247;H0Y9Y4;D6RAT0;D6R9B6;D6RG13;D6RB09;E9PFI5 P61247 RPS3A 40S ribosomal protein S3a 0 0 111.94 0.00083559 4314800 1742.5 964.49 1643.6 1594.3 908.54 2061.8 1121.6 1120.6 2419.7 2031.2 FALSE FALSE TRUE 1604.579286 1047.856218 1704.513262 1587.703209 897.7062539 1634.159439 1153.069077 1462.265781 2154.264964 2101.784049 0.763436799 0.498555605 0.810984013 0.755407393 0.427116313 0.777510629 0.548614439 0.695725987 1.024969699 1 11.03739873 -8.431277811 0.510072359 1.017559013 0.631403503 0.574854229 0.121960718 0.509544414 0.278152002 0.088730367 0.035758344 3.70E-09 8.431277811 -0.386155511 EVRS(ph)PTKAPHLQLIEGK ddPTM_HeLa_Curcumin_4h_R1 2 EVRSPTKAPHLQLIEGK 17 2 O43491;O43491-4;E9PHY5;E9PK52;O43491-3;O43491-2;E9PII3;A0A2R8Y5B3;H0Y5B0 O43491 EPB41L2 Band 4.1-like protein 2 1 0 EVRS(0.878)PT(0.122)KAPHLQLIEGK;EVRS(0.82)PT(0.18)KAPHLQLIEGK ; 50.053 0.015894 209440000 7388.9 5352.7 5988.6 6930.8 5941.8 8043.6 6531.1 4441.6 7896.4 6478.9 TRUE FALSE FALSE 6804.060768 5815.363537 6210.542784 6902.122186 5870.947916 6375.26669 6714.345088 5795.823393 7030.184676 6704.041293 1.014919281 0.867441485 0.926387907 1.029546491 0.87573266 0.950958744 1.001536953 0.864526804 1.048648773 1 12.71081532 -7.30520611 24.97988555 1.007045227 0.935867508 0.363503447 0.053512753 394.1389395 224954.1001 0.008315954 0.009509672 4.95E-08 7.30520611 -0.071177719 EVS(ph)DSEAGGGPQGER ddPTM_HeLa_Curcumin_4h_R1 1 EVSDSEAGGGPQGER 15 0 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 0 EVS(0.782)DS(0.218)EAGGGPQGER 131.61 0.00069257 17220000 525.71 530.68 612.43 430.29 646.85 526.14 474.39 406.83 421.03 313.53 TRUE FALSE FALSE 484.0994988 576.5496145 635.1271945 428.509574 639.1367362 417.0126332 487.7001066 530.8705942 374.8440624 324.4251442 1.492176262 1.7771422 1.957700277 1.320827259 1.970059188 1.285389375 1.503274686 1.636342323 1.15541002 1 8.341741828 -8.603639842 0.787922462 1.02918799 1.623608791 0.474743773 0.225935923 0.342759365 0.431317597 0.104729401 0.047567363 2.49E-09 8.603639842 0.594420801 EVS(ph)DSEAGGGPQGERK ddPTM_HeLa_Curcumin_4h_R1 2 EVSDSEAGGGPQGERK 16 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 0 EVS(0.999)DS(0.001)EAGGGPQGERK;EVS(0.994)DS(0.006)EAGGGPQGERK ; 94.281 0.0020592 33157000 4152 4882.5 4163.4 3751.8 4636 4464.6 4478.1 3272.2 3930 4145.8 TRUE FALSE FALSE 3823.364819 5304.521544 4317.699266 3736.276046 4580.718728 3538.591634 4603.743434 4269.878717 3498.888832 4289.866241 0.891255019 1.236523762 1.006488087 0.870953973 1.067799896 0.824872253 1.073167128 0.995340758 0.815617233 1 12.06671695 QEVGPPLPPLLAPLIAT(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 2 QEVGPPLPPLLAPLIATPPR 20 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 0 QEVGPPLPPLLAPLIAT(1)PPR;QEVGPPLPPLLAPLIAT(1)PPR ; 127.8 0.0002071 68593000 1178.22 986.98 1158.85 939.37 1016.91 1321.7 570.97 314.79 916.73 884.61 TRUE FALSE FALSE 1084.962644 1072.290153 1201.798 935.4831358 1004.784012 1047.564521 586.9898815 410.7680219 816.1670125 915.3501317 1.18529796 1.171453541 1.312938032 1.021994867 1.097704559 1.144441329 0.641273608 0.44875508 0.891644612 1 9.838179886 -4.662270816 3.664477693 1.111077716 0.485517622 0.804041705 0.111649651 0.063153951 1.572823019 0.01458764 0.06423445 2.18E-05 4.662270816 -0.625560094 down EVS(ph)PEVVR ddPTM_HeLa_Curcumin_4h_R1 5 EVSPEVVR 8 0 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 0 EVS(1)PEVVR;EVS(1)PEVVR;EVS(1)PEVVR;EVS(1)PEVVR;EVS(1)PEVVR ;;;; 166.34 0.00040151 1477386200 24701.7 20727.3 20106.2 21446.1 21167.6 24632.1 20822.3 18372.2 24184.8 20573 TRUE FALSE FALSE 22746.53438 22518.87545 20851.35346 21357.36172 20915.1902 19523.1248 21406.5177 23973.7992 21531.78795 21287.91022 1.068518899 1.057824616 0.979492738 1.003262486 0.98249147 0.91709917 1.005571589 1.126169688 1.011456161 1 14.37774671 -6.757340712 24.97212886 1.03517035 0.997758462 0.079694546 0.052036605 196.2067127 1195423.941 0.008725413 0.012092713 1.75E-07 6.757340712 -0.037411889 EVS(ph)PGSRDILDGVR ddPTM_HeLa_Curcumin_4h_R1 3 EVSPGSRDILDGVR 14 1 Q96RL1-2;Q96RL1;Q96RL1-3;Q96RL1-4 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 0 EVS(0.91)PGS(0.09)RDILDGVR;EVS(0.986)PGS(0.014)RDILDGVR;EVS(0.98)PGS(0.02)RDILDGVR ;; 73.597 0.012109 65831000 12685.6 9711.1 9469 11072.5 7867.4 12790.9 7440.3 4949.58 14495.2 11861.7 TRUE FALSE FALSE 11681.52137 10550.48421 9819.92947 11026.68493 7773.586393 10137.92316 7649.054793 6458.684157 12905.11283 12273.89319 0.951737252 0.859587422 0.800066394 0.898385276 0.633343168 0.82597453 0.623197112 0.526213163 1.051427825 1 13.58330531 -3.662018635 0.254295083 1.018929489 2.85E-16 0.818514863 0.070162614 3.558574744 0.141385069 0.039710399 1.19618861 0.000217762 3.662018635 -1.018929489 EVS(ph)PLLPK ddPTM_HeLa_Curcumin_4h_R1 2 EVSPLLPK 8 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 0 EVS(1)PLLPK;EVS(1)PLLPK ; 116.52 0.0093622 70111000 23668.3 14868 22959.4 22784 24971.5 23999.3 17940.7 8515.5 21898.2 18706.7 TRUE FALSE FALSE 21794.92908 16153.12367 23810.29556 22689.72584 24673.73117 19021.57465 18444.06776 11111.83675 19496.02225 19356.75643 1.125959773 0.834495372 1.230076725 1.172186359 1.274683145 0.98268399 0.95284909 0.574054687 1.007194688 1 14.2405496 -4.195974667 1.786791581 1.07679296 0.351956064 0.607460002 0.122601377 0.558572688 1.548143871 0.017583379 0.717361887 6.37E-05 4.195974667 -0.724836895 EVS(ph)PLLPKLPEEPEAESK ddPTM_HeLa_Curcumin_4h_R1 1 EVSPLLPKLPEEPEAESK 18 1 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 0 EVS(0.999)PLLPKLPEEPEAES(0.001)K 72.99 0.0051202 21604000 2999.7 1777.3 2348.7 2569.8 2408.8 2962.2 1981.6 1262.7 4002.8 3029.4 TRUE FALSE FALSE 2762.27058 1930.921893 2435.744888 2559.166849 2380.076633 2347.806329 2037.198363 1647.691417 3563.702855 3134.671425 0.8811994 0.61598861 0.777033557 0.81640673 0.759274677 0.74898004 0.649892154 0.525634491 1.136866476 1 11.61409851 -4.060051893 0.100059776 1.230161054 7.07E-15 0.740790165 0.087595275 21.795038 0.33445856 0.943985476 4.03932793 8.71E-05 4.060051893 -1.230161054 EVS(ph)PPGAR ddPTM_HeLa_Curcumin_4h_R1 1 EVSPPGAR 8 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 EVS(1)PPGAR 106.68 0.012264 267320000 1166.3 881.77 1079.9 950.38 970.05 1277.9 1170.1 835.1 1198.3 1111.4 TRUE FALSE FALSE 1073.986124 957.9862697 1119.922044 946.4475794 958.4827873 1012.849135 1202.929857 1089.718146 1066.849488 1150.021067 0.93388387 0.833016279 0.973827416 0.822982819 0.833448025 0.880722244 1.0460068 0.947563637 0.927678212 1 10.16744457 -8.374592968 0.93929275 0.991198901 0.906921614 0.063993251 0.06989893 0.591446672 1.08535922 0.024181964 0.014756228 4.22E-09 8.374592968 -0.084277288 EVS(ph)TYIKK ddPTM_HeLa_Curcumin_4h_R1 2 EVSTYIKK 8 1 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 1 0 EVS(0.994)T(0.006)YIKK;EVS(0.887)T(0.113)YIKK ; 111.65 0.0070051 16363000 2760 1925.12 2279.89 2796.7 3238.3 2986 2185.7 1829.32 2930 2372 TRUE FALSE FALSE 2541.543088 2091.518795 2364.384729 2785.127996 3199.685388 2366.669941 2247.024859 2387.071247 2608.58633 2454.426823 1.035493527 0.852141435 0.963314411 1.134736619 1.303638535 0.964245468 0.91549882 0.972557513 1.062808761 1 11.26117044 EVSKPVGGAEGVEVPRS(ph)PVLLCK ddPTM_HeLa_Curcumin_4h_R1 2 EVSKPVGGAEGVEVPRSPVLLCK 23 2 Q8TED9-3;Q8TED9-2;Q8TED9 Q8TED9-3 AFAP1L1 Actin filament-associated protein 1-like 1 1 0 EVSKPVGGAEGVEVPRS(1)PVLLCK;EVSKPVGGAEGVEVPRS(1)PVLLCK ; 107.91 5.47E-06 69347000 4885.6 3899.3 4104.2 4286.9 4343.2 5442.1 3671.2 1884.36 5392.3 4036.9 TRUE FALSE FALSE 4498.899605 4236.338117 4256.305262 4269.161944 4291.410177 4313.347115 3774.203991 2458.892689 4800.778181 4177.181975 1.077017863 1.014161735 1.018941786 1.022019622 1.027345757 1.032597369 0.903528746 0.588648688 1.149286339 1 12.02831428 -4.257263452 1.997921755 1.032977522 0.452899874 0.915050812 0.04191549 0.106704706 0.444609302 0.004167819 0.113267172 5.53E-05 4.257263452 -0.580077648 EVSPDPS(ph)TTGAASPASSSAGGSAAR ddPTM_HeLa_Curcumin_4h_R1 1 EVSPDPSTTGAASPASSSAGGSAAR 25 0 P23769-2;P23769 P23769-2 GATA2 Endothelial transcription factor GATA-2 1 0 EVSPDPS(0.969)T(0.026)T(0.001)GAAS(0.001)PAS(0.002)S(0.001)S(0.001)AGGSAAR 149.6 3.45E-08 4933200 978.6 563.26 1156.9 1292.1 1345.4 1418.4 1044.4 504.2 1310.8 1182 TRUE FALSE FALSE 901.1427774 611.9456846 1199.775732 1286.753633 1329.356984 1124.207851 1073.703053 657.9282589 1167.008519 1223.074412 0.736784916 0.500333977 0.980950725 1.052064878 1.086897879 0.919165539 0.877872223 0.53792987 0.954159868 1 10.25629646 -4.261746332 6.798203931 0.884422464 0.532177824 0.303059805 0.163452783 0.12754993 40.7132844 0.025167477 0.205998451 5.47E-05 4.261746332 -0.352244639 QFSSCS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 QFSSCSPR 8 0 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6;V9GXZ1;Q9Y2H9 Q6P0Q8 MAST2;MAST1 Microtubule-associated serine/threonine-protein kinase 2;Microtubule-associated serine/threonine-protein kinase 1 1 0 QFSSCS(1)PR 91.701 0.01991 20174000 3709.8 2817.6 3185.9 2997.2 3144.5 3392.7 1909.3 1119.2 3082.8 2911.7 TRUE FALSE FALSE 3416.165415 3061.140789 3303.972257 2984.798381 3107.003891 2689.015776 1962.869819 1460.438928 2744.624553 3012.881358 1.133853282 1.0160177 1.096615453 0.99067903 1.03124004 0.892506361 0.65149257 0.484731642 0.910963369 1 11.55692815 -4.661151596 1.240199697 1.060447405 0.398761212 0.895586773 0.06234836 0.137358142 0.279360089 0.008051449 0.096251333 2.18E-05 4.661151596 -0.661686194 down EVSSLEGS(ph)PPPCLGQEEAVCTK ddPTM_HeLa_Curcumin_4h_R1 1 EVSSLEGSPPPCLGQEEAVCTK 22 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 EVSS(0.001)LEGS(0.999)PPPCLGQEEAVCTK 192.12 2.34E-13 36083000 5422.6 4877.9 4597.2 5067.6 4618.5 5670.9 4603.2 4206.8 5119.6 5269.1 TRUE FALSE FALSE 4993.395488 5299.52394 4767.576276 5046.631614 4563.427404 4494.691416 4732.353403 5489.433954 4557.992689 5452.200833 0.915849515 0.971997199 0.874431523 0.925613668 0.836988134 0.824381118 0.867971219 1.006829008 0.835991342 1 12.41262299 -8.622199345 0.377329445 1.01691962 0.883374217 0 0.072937514 1.434164281 0.388619336 0.078877992 0.024039004 2.39E-09 8.622199345 -0.133545404 EVSTAPAGTDMPAAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EVSTAPAGTDMPAAKK 16 1 H0YEL4;E9PJK2;A0A5F9ZI63;O75530-3;O75530;O75530-2 H0YEL4 EED Polycomb protein EED 0 1 ; EVSTAPAGTDMPAAK(1)K;EVSTAPAGTDMPAAK(1)K 287.29 3.43E-112 8087800 4334.1 4727 4805.4 4686.7 4631.9 5911.4 4689.8 5200.7 4798.7 4042.4 FALSE TRUE FALSE 3991.051412 5135.580817 4983.492351 4667.307677 4576.667618 4685.309005 4821.383166 6786.369489 4272.294616 4182.873099 0.954141165 1.227763954 1.191404146 1.115813836 1.094144505 1.120117415 1.152648682 1.622418211 1.021378013 1 12.03027851 -1 0.670080809 1.019281536 58.01193533 0.701610993 0.096723779 95.18390472 0.528835881 0.018729465 8096.668457 0.1 1 56.9926538 EVSTYIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EVSTYIKK 8 1 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 1 ; EVSTYIK(1)K;EVSTYIK(1)K 190.26 8.34E-22 141504000 10008.8 9561.6 8302.6 8353.6 12193.4 14849 13256.8 12829.7 15442.4 7918.7 FALSE TRUE FALSE 9216.592919 10388.0621 8610.30166 8319.035017 12048.00167 11769.15002 13628.75013 16741.41647 13748.40735 8193.874236 1.124815033 1.267783932 1.050821798 1.015274921 1.470366926 1.436335203 1.663285247 2.043162488 1.677888501 1 13.00033003 -1 0.38970067 1.043018306 16.77200468 0.534269932 0.224622047 12.49717167 0.149802801 0.026207129 151.3981018 0.1 1 15.72898638 EVSTYIKK ddPTM_HeLa_Curcumin_4h_R1 2 EVSTYIKK 8 1 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 0 ; ; 84.568 0.0098855 69323000 14067.5 9204.8 10469.9 11059.3 10142.8 12792.8 8990.9 10797.9 13002.5 10827.3 FALSE FALSE TRUE 12954.04253 10000.4219 10857.9237 11013.53955 10021.85373 10139.42908 9243.160456 14090.13 11576.15828 11203.54787 1.156244672 0.892612056 0.969150472 0.983040344 0.894525007 0.905019481 0.825020838 1.257648931 1.033258251 1 13.45166805 -7.254823709 24.97724428 1.073782206 0.952223367 0.135980966 0.115628007 632.8058394 2389138.68 0.019211684 0.023230545 5.56E-08 7.254823709 -0.121558839 EVTPEGLQMVK ddPTM_HeLa_Curcumin_4h_R1 2 EVTPEGLQMVK 11 0 E9PBS1;P22234;P22234-2;D6RF62 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 0 0 ; ; 174.41 4.34E-34 1955200 2691.7 1783.12 2079.3 2294 2362.4 2518.6 2176.8 2029.03 2294.91 1851.68 FALSE FALSE TRUE 2478.649105 1937.244947 2156.360687 2284.508036 2334.229923 1996.21397 2237.875149 2647.671906 2043.164115 1916.025742 1.293640816 1.011074593 1.12543409 1.192315941 1.218266473 1.041851331 1.167977601 1.381856124 1.066355253 1 10.90390123 -9.588998165 1.369450472 0.999702476 1.185499355 0.228487024 0.104764328 0.441749992 1.482042622 0.075544516 0.01743361 2.58E-10 9.588998165 0.185796879 EVVEEAENGR ddPTM_HeLa_Curcumin_4h_R1 4 EVVEEAENGR 10 0 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA "Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1" 0 0 ;;; ;;; 209.6 9.94E-27 175737000 12343.9 10853.4 11583.5 11658.3 13673.7 15638.2 12833.7 11240.7 11510.4 10518.2 FALSE FALSE TRUE 11366.86729 11791.51953 12012.7947 11610.06104 13510.65006 12394.66104 13193.77908 14667.93768 10247.73792 10883.70667 1.044393021 1.083410266 1.10374113 1.066737776 1.241364773 1.138827186 1.212250521 1.347696895 0.941566897 1 13.40988236 -1 0.227357842 0.992846474 2.83298644 0.840490374 0.04585032 11.59662677 0.140471645 0.026216397 7.992768915 0.1 1 1.840139966 EVVKPVPIT(ph)SPAVSK ddPTM_HeLa_Curcumin_4h_R1 1 EVVKPVPITSPAVSK 15 1 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 0 EVVKPVPIT(0.703)S(0.277)PAVS(0.02)K 185.86 0.00019696 275210000 2775.7 2341.4 2594 2906.8 2429.7 4097.1 4045.7 1411.3 2684.7 2273.3 TRUE FALSE FALSE 2556.000416 2543.780183 2690.135922 2894.772432 2400.727414 3247.315276 4159.211454 1841.598873 2390.195127 2352.297006 1.086597657 1.081402636 1.143620859 1.230615192 1.02058856 1.380486932 1.768148938 0.782893856 1.016111112 1 11.19985451 -6.102816224 0.738370461 1.035708622 1.320840052 0.126469529 0.236892254 0.876235562 0.91447615 0.043892504 0.123749566 7.89E-07 6.102816224 0.28513143 EVVKPVPITS(ph)PAVSK ddPTM_HeLa_Curcumin_4h_R1 2 EVVKPVPITSPAVSK 15 1 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 0 EVVKPVPIT(0.084)S(0.916)PAVSK;EVVKPVPIT(0.057)S(0.77)PAVS(0.174)K ; 158.14 0.00078893 238613300 6418.08 5323.94 5758.85 6228.6 5537.47 9218 7674.4 3616.78 6651.2 5386.84 TRUE FALSE FALSE 5910.082196 5784.117651 5972.278047 6202.827704 5471.439287 7306.082892 7889.723009 4719.519572 5921.58 5574.032289 1.060288475 1.037690015 1.071446618 1.112807996 0.981594473 1.31073566 1.415442646 0.846697566 1.06235122 1 12.44450564 -5.269888098 24.96463855 1.036879893 1.213407028 0.174073328 0.140478128 585.3424938 1729597.041 0.018305876 0.041541969 5.37E-06 5.269888098 0.176527135 EVVKPVPITSPAVSK ddPTM_HeLa_Curcumin_4h_R1 2 EVVKPVPITSPAVSK 15 1 Q96HC4;A0A0D9SFR4 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 0 0 ; ; 161.08 0.0005467 6738700 6128.2 5112.8 5273.1 5959.7 5012.4 6242.4 4837.4 5367.3 6610.8 4940.3 FALSE FALSE TRUE 5643.146504 5554.72765 5468.525725 5935.040341 4952.630404 4947.655874 4973.124425 7003.765062 5885.611779 5111.975057 1.103907284 1.086610867 1.069748123 1.161007296 0.968829141 0.967856028 0.972838163 1.370070273 1.151338125 1 12.31966508 -9.394710728 1.087903653 0.99942438 1.079697191 0 0.122338749 1.246048029 2.608110471 0.076886525 0.019080995 4.03E-10 9.394710728 0.08027281 EVVSFS(ph)PDPLPVR ddPTM_HeLa_Curcumin_4h_R1 1 EVVSFSPDPLPVR 13 0 J3QLG5;F8W925;Q8NFI3-2;Q8NFI3-3;Q8NFI3 J3QLG5 ENGASE Cytosolic endo-beta-N-acetylglucosaminidase 1 0 EVVS(0.112)FS(0.888)PDPLPVR 99.844 0.0071216 2250600 1151.1 1191.1 1114.5 1372.6 1227.7 1451.3 1198.3 1007.7 1290.3 1220.8 TRUE FALSE FALSE 1059.98922 1294.053377 1155.80435 1366.920545 1213.060479 1150.28402 1231.921073 1314.943091 1148.757318 1263.222709 0.839115077 1.024406359 0.914964829 1.082089908 0.960290272 0.910594792 0.975220809 1.040943202 0.909386215 1 10.3028933 -7.228450005 24.99636894 0.924026535 0.983411193 0.210095094 0.062058915 1048.66172 794582.2633 0.012525979 0.015340571 5.91E-08 7.228450005 0.059384657 EVWYFGLHYVDNK ddPTM_HeLa_Curcumin_4h_R1 2 EVWYFGLHYVDNK 13 0 E7EQR4;P15311 E7EQR4 EZR Ezrin 0 0 ; ; 107.53 0.0036541 20837700 2926.95 2455.87 2352.97 2297.47 2612.51 9454 4850.9 4886.9 2971.5 2651.89 FALSE FALSE TRUE 2695.278819 2668.14446 2440.173138 2287.963678 2581.357525 7493.133831 4987.003198 6376.893313 2645.533884 2744.04298 0.982229083 0.972340623 0.889261996 0.833792945 0.940713226 2.730691132 1.817392524 2.323904312 0.964100746 1 11.42208736 -5.274584891 24.99733663 0.966996997 2.243335629 0.894281888 0.212431044 148.6994075 282764.8027 0.027000401 0.060714525 5.31E-06 5.274584891 1.276338632 EVYELLDS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 4 EVYELLDSPGK 11 0 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 0 EVYELLDS(1)PGK;EVY(0.011)ELLDS(0.989)PGK;EVYELLDS(1)PGK;EVYELLDS(1)PGK ;;; 184.98 9.20E-05 357511200 20943.5 18564.1 20140.1 20068 24512.2 34494.1 32701.5 12014.9 18512 15524.5 TRUE FALSE FALSE 19285.79988 20168.69808 20886.50982 19984.96393 24219.90802 27339.63483 33619.01608 15678.1877 16481.27991 16063.97522 1.200562103 1.255523481 1.300208045 1.244085829 1.507715724 1.701922124 2.092820464 0.975984306 1.025977673 1 13.97154133 -6.380031146 0.578239256 1.061368998 1.647155161 0.350884474 0.268307169 0.625092547 0.411706242 0.064166028 0.158583631 4.17E-07 6.380031146 0.585786163 EVYELLDS(ph)PGKVLLQSK ddPTM_HeLa_Curcumin_4h_R1 2 EVYELLDSPGKVLLQSK 17 1 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 0 EVYELLDS(1)PGKVLLQSK;EVYELLDS(1)PGKVLLQSK ; 116.21 0.00035086 396540000 14230.6 11148.3 10677.1 11873 9653 22358.2 19379.7 7900 14475.1 11962.2 TRUE FALSE FALSE 13104.23299 12111.90938 11072.80272 11823.87267 9537.89428 17720.85729 19923.44222 10308.67363 12887.21774 12377.88556 1.058681059 0.978511986 0.894563346 0.955241718 0.770559255 1.43165464 1.609599808 0.832829936 1.041148562 1 13.59547727 -5.248784465 24.98301831 0.993869325 1.323185306 0.355934596 0.20054371 604.8899588 1194156.15 0.026181592 0.066259656 5.64E-06 5.248784465 0.32931598 EVYQQQQYGS(ph)GGR ddPTM_HeLa_Curcumin_4h_R1 2 EVYQQQQYGSGGR 13 0 Q99729-3;Q99729-4;D6R9P3;D6RD18;D6RBZ0;Q99729-2;Q99729 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 0 EVYQQQQYGS(1)GGR;EVYQQQQYGS(1)GGR ; 230.57 1.61E-19 123687000 1689.11 1637.17 1562.96 1748.92 1887.91 3557.2 3791.9 1375.11 1777.24 1587.43 TRUE FALSE FALSE 1555.415161 1778.67968 1620.884673 1741.683432 1865.397906 2819.396622 3898.290509 1794.374709 1582.281218 1642.593074 0.946926652 1.082848642 0.986784066 1.060325567 1.135642135 1.71643036 2.373253954 1.092403674 0.963282534 1 10.68175941 -5.299130005 3.477881337 0.993430147 1.804808597 0.549677835 0.291344652 0.10828821 2.715464634 0.037015855 0.093123131 5.02E-06 5.299130005 0.811378449 EVYQQQQYGSGGR ddPTM_HeLa_Curcumin_4h_R1 3 EVYQQQQYGSGGR 13 0 Q99729-3;Q99729-4;D6R9P3;D6RD18;D6RBZ0;Q99729-2;Q99729 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 0 0 ;; ;; 227.48 1.68E-37 6733000 2102.99 1753.88 2185.82 1853.26 2174.84 2370.05 1872.54 2090.94 2265.38 2144.11 FALSE FALSE TRUE 1936.536122 1905.477572 2266.828412 1845.591701 2148.906453 1878.474914 1925.078433 2728.45798 2016.873482 2218.617663 0.872857074 0.85885802 1.021730084 0.831865595 0.968578989 0.846687082 0.867692737 1.229800892 0.909067621 1 11.11544535 -4.254990712 24.95581808 0.92375641 1.229801032 0.68388051 0.0647812 362.8105552 1404008.279 0.009708362 0.124132298 5.56E-05 4.254990712 0.306044622 EWNGVVSESDS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 1 EWNGVVSESDSPVK 14 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;M0QY71;M0R1G7;F5GZ28 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 EWNGVVSESDS(1)PVK 170.09 0.00020337 27569000 2549 2422.5 2969.8 2490.8 3428.4 3369.7 3546.1 1706.2 2434.1 1914.9 TRUE FALSE FALSE 2347.24396 2631.890106 3079.863401 2480.49373 3387.518569 2670.786236 3645.594022 2226.412526 2167.08532 1981.442632 1.184613635 1.328269647 1.55435406 1.251862501 1.70962233 1.347899854 1.83986857 1.12363209 1.09369067 1 10.95233548 -7.364949949 0.74510115 1.03712065 1.506227668 0.41344076 0.200816004 0.329361519 0.384194674 0.047868526 0.053276768 4.32E-08 7.364949949 0.469107018 EWNGVVSESDS(ph)PVKRPGR ddPTM_HeLa_Curcumin_4h_R1 1 EWNGVVSESDSPVKRPGR 18 2 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;M0QY71;M0R1G7;F5GZ28 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 EWNGVVS(0.029)ES(0.071)DS(0.9)PVKRPGR 72.167 0.0089779 42356000 2166.1 1533 1729.5 2276.1 1833.7 2860.1 2160.5 1236 2129.6 2051.1 TRUE FALSE FALSE 1994.650899 1665.505689 1793.596791 2266.682101 1811.834325 2266.88302 2221.117815 1612.85071 1895.988208 2122.375572 0.939819948 0.784736552 0.845089255 1.067992928 0.853682236 1.068087595 1.046524397 0.759927098 0.893333033 1 11.05146426 -8.613150606 1.208795818 0.99150555 0.927693908 0 0.111516884 0.966387885 2.840409544 0.034215101 0.020083171 2.44E-09 8.613150606 -0.063811643 EWQHEEFYR ddPTM_HeLa_Curcumin_4h_R1 2 EWQHEEFYR 9 0 I3L0K7;Q12931-2;Q12931;I3L239 I3L0K7 TRAP1 "Heat shock protein 75 kDa, mitochondrial" 0 0 ; ; 160.75 0.0005683 19075000 6486.3 5219.2 6544.5 6027.8 7279.2 10142.2 6416.1 5485.5 7300.3 5217.2 FALSE FALSE TRUE 5972.902511 5670.324392 6787.044927 6002.858561 7192.400294 8038.593394 6596.118498 7158.003698 6499.475354 5398.497312 1.106400942 1.05035236 1.257210023 1.111949903 1.332296726 1.489042771 1.221843435 1.325925213 1.203941575 1 12.39834217 -6.389647307 0.67466187 1.035213126 1.353659482 0.483473678 0.101282738 0.314099956 0.282899457 0.01933732 0.044468054 4.08E-07 6.389647307 0.318446356 EWSLESSPAQNWT(ph)PPQPR ddPTM_HeLa_Curcumin_4h_R1 2 EWSLESSPAQNWTPPQPR 18 0 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;E5RHT6;E5RHC5;F8W1U7;Q8N6T3-3 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 0 EWSLESS(0.001)PAQNWT(0.999)PPQPR;EWSLESSPAQNWT(1)PPQPR ; 150.9 0.00024812 24774000 4856.8 4795.6 4539.3 4967.4 4718.6 5479.2 4157.3 3150.98 5906.7 4855 TRUE FALSE FALSE 4472.379155 5210.110295 4707.530451 4946.846215 4662.333777 4342.752157 4273.942649 4111.699297 5258.749788 5023.710889 0.890254088 1.037103928 0.937062374 0.984699622 0.928065703 0.864451051 0.850754103 0.818458583 1.046785913 1 12.29453773 -5.215318301 2.088642469 0.955927088 0.834575956 0.60066658 0.047843898 0.199764081 1.669647968 0.007059483 0.022590482 6.09E-06 5.215318301 -0.121351133 EWTDGLFTHVLR ddPTM_HeLa_Curcumin_4h_R1 1 EWTDGLFTHVLR 12 0 Q14204;A0A2R8YFZ7 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 0 140.45 0.00038511 0 5706.8 4517.8 5643.1 3951 4375.3 14079 9108.2 6173 5427.5 5297.5 FALSE FALSE TRUE 5255.100758 4908.298501 5852.23825 3934.651809 4323.127405 11158.8567 9363.751579 8055.119283 4832.116829 5481.587731 0.958682232 0.895415479 1.067617365 0.717794187 0.788663361 2.035697912 1.708218866 1.469486521 0.88151774 1 12.42037811 -5.267721207 25 0.948953423 1.734842885 0.845795767 0.162775827 134.6189949 535748.5045 0.022664671 0.051871335 5.40E-06 5.267721207 0.785889462 EWVESMGGK ddPTM_HeLa_Curcumin_4h_R1 2 EWVESMGGK 9 0 P50502;Q3KNR6;Q8NFI4 P50502 ST13;ST13P5 Hsc70-interacting protein;Putative protein FAM10A5 0 0 ; ; 172.21 1.21E-21 2146100 3025.1 2383.4 2836.2 2718 2630.4 3238 2593.4 2429.4 2811.9 2632.8 FALSE FALSE TRUE 2785.660143 2589.410476 2941.312067 2706.753636 2599.034198 2566.4023 2666.163824 3170.112876 2503.441605 2724.289604 1.022527171 0.950490165 1.079662038 0.993563104 0.954022727 0.942044596 0.978663876 1.163647533 0.918933729 1 11.41166436 EWYGWHFPELGK ddPTM_HeLa_Curcumin_4h_R1 1 EWYGWHFPELGK 12 0 Q9Y2X3;H7BZ72 Q9Y2X3 NOP58 Nucleolar protein 58 0 0 90.697 0.011577 5209200 5284.8 3982.7 4716.8 4304 5313.3 6674.6 4637.8 3320.1 4193.5 4721.3 FALSE FALSE TRUE 4866.502504 4326.946841 4891.608757 4286.191188 5249.942368 5290.212722 4767.924186 4332.383206 3733.483542 4885.364824 0.996139015 0.885695746 1.00127809 0.877353349 1.074626473 1.082869532 0.975960723 0.886808532 0.76421796 1 12.25425059 -7.481768532 24.99520483 0.998296695 0.973132162 0 0.101098868 1608.175637 977784.2794 0.011886011 0.01344472 3.30E-08 7.481768532 -0.025164533 EWYQETHEK ddPTM_HeLa_Curcumin_4h_R1 1 EWYQETHEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 0 160.53 0.00058543 14489000 4241.3 4245.8 3829.8 4868 4159.7 5210.7 4130.6 3505.1 4016.8 4239.8 FALSE FALSE TRUE 3905.59663 4612.788033 3971.735757 4847.857506 4110.098294 4129.942083 4246.493519 4573.788855 3576.16709 4387.132734 0.890238993 1.051435713 0.9053147 1.105017286 0.936852961 0.941376141 0.967942795 1.042546267 0.815149052 1 12.09906264 -7.265516092 24.98006114 0.948168416 0.988767748 0.161537946 0.075105953 731.3523535 4481361.121 0.011145756 0.012985157 5.43E-08 7.265516092 0.040599332 EY(ph)ADY(ph)ES(ph)LVEIISQKV ddPTM_HeLa_Curcumin_4h_R1 1 EYADYESLVEIISQKV 16 1 X6RKB4;Q9UGC7-3;Q9UGC7 X6RKB4 MTRF1L "Peptide chain release factor 1-like, mitochondrial" 3 0 EY(1)ADY(1)ES(0.999)LVEIIS(0.001)QKV 76.522 0.0036353 0 2604.9 2507.6 2007.1 2003.6 2545.2 3469.9 2261.6 2028.3 2843.5 2340.8 TRUE FALSE FALSE 2398.719416 2724.34577 2081.484892 1995.309634 2514.850152 2750.203626 2325.054409 2646.719333 2531.575164 2422.142626 0.99032955 1.124766866 0.859356864 0.823778754 1.038275007 1.135442478 0.959916392 1.092718201 1.045180056 1 11.2420681 -5.540985234 24.99134313 0.981916343 1.0581555 0.167330154 0.090362311 358.4118275 494693.9217 0.012838591 0.025681219 2.88E-06 5.540985234 0.076239158 EY(ph)VVY(ph)DLK ddPTM_HeLa_Curcumin_4h_R1 1 EYVVYDLK 8 0 Q401N2 Q401N2 ZACN Zinc-activated ligand-gated ion channel 2 0 EY(1)VVY(1)DLK 62.464 0.0070986 0 3062.7 2953.7 3140 3185.7 2752.1 3454.9 2559.3 1816.7 4045.9 2955.9 TRUE FALSE FALSE 2820.284063 3209.004667 3256.371162 3172.518417 2719.283005 2738.314795 2631.10707 2370.603467 3602.074892 3058.617305 0.92207811 1.049168414 1.064654658 1.037239413 0.889056307 0.895278658 0.860227615 0.775057234 1.177680806 1 11.57866389 -4.922319144 1.19242466 0.980582098 0.785091008 0.499280381 0.080112742 0.377165145 0.830559642 0.009166696 0.067833023 1.20E-05 4.922319144 -0.19549109 EYAENIGDGRS(ph)PEFR ddPTM_HeLa_Curcumin_4h_R1 2 EYAENIGDGRSPEFR 15 1 A0A087WUB9;Q8WYA6-3;Q8WYA6-2;Q8WYA6-4;Q8WYA6 A0A087WUB9 CTNNBL1 Beta-catenin-like protein 1 1 0 EYAENIGDGRS(1)PEFR;EYAENIGDGRS(1)PEFR ; 100.69 0.0016288 43889000 3472.2 3737.7 3738.3 3786.4 3930.5 4224.4 3854.8 3541.7 3243.2 2638 TRUE FALSE FALSE 3197.371706 4060.770133 3876.844687 3770.73288 3883.631355 3348.211821 3962.955313 4621.548026 2887.429074 2729.670304 1.171339887 1.487641247 1.420261151 1.381387662 1.42274741 1.22659935 1.451807315 1.693079204 1.057794075 1 11.41451099 -7.550722427 1.437890783 1.053281776 1.432329497 0.672776818 0.115792635 0.160938165 0.669412489 0.024831647 0.026109527 2.81E-08 7.550722427 0.37904772 EYFNSS(ph)T(ph)NLT(ph)DSCMDLAR ddPTM_HeLa_Curcumin_4h_R1 1 EYFNSSTNLTDSCMDLAR 18 0 C9JCM7;H0Y5G7;A2RRP1-2;A2RRP1 C9JCM7 NBAS Neuroblastoma-amplified sequence 3 0 EY(0.075)FNS(0.26)S(0.928)T(0.818)NLT(0.874)DS(0.045)CMDLAR 44.567 0.019022 31851000 1105.2 1104.1 736.48 986.17 1172 909.99 736.55 911.52 901.32 900.97 TRUE FALSE FALSE 1017.722254 1199.533484 763.7745967 982.0894898 1158.024665 721.2478163 757.2156107 1189.438252 802.447451 932.2786404 1.091650296 1.286668419 0.819255707 1.053429144 1.242144371 0.773639752 0.812220272 1.275839862 0.860737784 1 9.864617403 -5.256070681 24.96329773 1.057952913 0.939732019 0.051463417 0.185320358 849.6880897 3950852.432 0.023323391 0.05754249 5.55E-06 5.256070681 -0.118220894 EYFSWEGAFQHVGK ddPTM_HeLa_Curcumin_4h_R1 2 EYFSWEGAFQHVGK 14 0 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 0 ; ; 185.2 4.46E-05 204360000 7114.2 5433.9 6511.4 5506.9 6502.9 9462.5 6691.3 7329.4 6264.6 6010.3 FALSE FALSE TRUE 6551.103563 5903.582103 6752.718212 5484.113907 6425.357165 7499.870836 6879.039869 9564.10032 5577.389053 6219.157478 1.053374768 0.949257536 1.08579309 0.881809783 1.033155566 1.205930363 1.106104789 1.537845014 0.896807819 1 12.60250343 -1.000004478 0.860197279 1.016305202 196.110415 0.789320331 0.0827703 201.0399519 0.505996158 0.010868256 76840.15405 0.099998969 1.000004478 195.0941098 EYGS(ph)PLKAYT(ph)PVVVTQWYR ddPTM_HeLa_Curcumin_4h_R1 2 EYGSPLKAYTPVVVTQWYR 19 1 Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;Q9UQ88-5;Q9UQ88-10 Q5QPR4 CDK11A Cyclin-dependent kinase 11A 2 0 EY(0.068)GS(0.936)PLKAY(0.001)T(0.985)PVVVT(0.01)QWYR;EY(0.043)GS(0.977)PLKAY(0.005)T(0.962)PVVVT(0.013)QWYR ; 78.531 0.0075943 74187000 6186.2 4962.1 5255.1 4916.9 4261.8 14309.9 8941 2580.6 6455.6 5939.6 TRUE FALSE FALSE 5696.555742 5391.001813 5449.858629 4896.555171 4210.980818 11341.86543 9191.860397 3367.41306 5747.436831 6146.000658 0.926871971 0.877156075 0.886732516 0.79670593 0.685157886 1.845405828 1.495584024 0.54790314 0.935150702 1 12.58543221 -5.294543553 24.99974165 0.92272207 1.316226891 0.266848439 0.313744002 621.2390279 469148.787 0.042674712 0.095428923 5.08E-06 5.294543553 0.39350482 EYGS(ph)TSSIDK ddPTM_HeLa_Curcumin_4h_R1 1 EYGSTSSIDK 10 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 EYGS(0.928)T(0.069)S(0.003)SIDK 177.57 0.00035698 27203000 2870.9 2502.4 3085.1 2726.1 3121.4 3227.2 2952.9 2955.6 2487.9 2440.3 TRUE FALSE FALSE 2643.665236 2718.696306 3199.43652 2714.820121 3084.179344 2557.842342 3035.750427 3856.748834 2214.983594 2525.100243 1.046954568 1.076668664 1.26705327 1.075133602 1.221408675 1.012966653 1.202229668 1.527364644 0.877186401 1 11.30212495 -1 0.760797322 1.051408301 89.52930901 0.622696994 0.105949249 168.0933175 0.650838604 0.015499941 25547.17732 0.1 1 88.47790071 EYGS(ph)TSSIDR ddPTM_HeLa_Curcumin_4h_R1 2 EYGSTSSIDR 10 0 Q9P2F8 Q9P2F8 SIPA1L2 Signal-induced proliferation-associated 1-like protein 2 1 0 EYGS(0.951)T(0.047)S(0.002)SIDR;EYGS(0.698)T(0.204)S(0.098)SIDR ; 139.76 0.0015533 25789000 4731.7 4514 4586.1 4940.3 4745 5876.3 4291.6 2712.77 4615 4943.1 TRUE FALSE FALSE 4357.180952 4904.170046 4756.0649 4919.858348 4688.418974 4657.48914 4412.010746 3539.881085 4108.746046 5114.872357 0.851865041 0.958805949 0.929850164 0.961873143 0.916624824 0.910577785 0.862584721 0.692076134 0.803293955 1 12.32048252 -4.008205591 1.34824228 0.932415012 0.455418353 0.597820379 0.054407207 1.113119222 1.130735926 0.007920789 0.850169213 9.81E-05 4.008205591 -0.476996659 EYGSQEGKHDYDDS(ph)SEEQSAEDSYEASPGSETQR ddPTM_HeLa_Curcumin_4h_R1 1 EYGSQEGKHDYDDSSEEQSAEDSYEASPGSETQR 34 1 P98175-5;P98175-2;P98175 P98175-5 RBM10 RNA-binding protein 10 1 0 EY(0.003)GS(0.003)QEGKHDY(0.011)DDS(0.326)S(0.326)EEQS(0.326)AEDS(0.004)Y(0.001)EASPGSETQR 64 8.89E-05 10180000 1242.9 789.66 954.51 889.8 1085.1 1440.8 1101.3 853.04 981.07 695.32 TRUE FALSE FALSE 1144.523153 857.9146917 989.8849803 886.1182434 1072.160891 1141.961839 1132.199514 1113.127969 873.4490755 719.4823182 1.590759251 1.192405525 1.375829475 1.23160531 1.490183795 1.58719931 1.573630769 1.547123454 1.213996582 1 9.490815422 -9.440373505 0.970980808 0.977266239 1.454581514 0.429798522 0.149905639 0.364951714 0.566050488 0.13046674 0.026909503 3.63E-10 9.440373505 0.477315275 EYGST(ph)SSIDK ddPTM_HeLa_Curcumin_4h_R1 1 EYGSTSSIDK 10 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 EYGS(0.142)T(0.523)S(0.069)S(0.266)IDK 181.4 0.00081243 61613000 3789.4 3244 3433.4 3044.9 4110 4080.4 3775.2 3539.1 3273.1 3171.2 TRUE FALSE FALSE 3489.464991 3524.396905 3560.644824 3032.301011 4060.990934 3234.079044 3881.121952 4618.155298 2914.049119 3281.398964 1.06340772 1.074053153 1.085099637 0.92408788 1.237579148 0.985579346 1.182764423 1.407373912 0.888050844 1 11.6800953 -1.000001265 0.829765377 1.036895967 117.806919 0.606572822 0.09285238 238.595123 0.686410333 0.011602671 52539.07901 0.099999709 1.000001265 116.7700231 EYIPGQPPLS(ph)QSSDSSPTRNSEPAGLETPEAK ddPTM_HeLa_Curcumin_4h_R1 1 EYIPGQPPLSQSSDSSPTRNSEPAGLETPEAK 32 1 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 0 EYIPGQPPLS(0.244)QS(0.203)S(0.203)DS(0.049)S(0.049)PT(0.049)RNS(0.203)EPAGLET(0.002)PEAK 52.669 0.0018246 18305000 12492 8272.5 8295 10703 8072.5 11792 7541.8 8165 14208 11834 TRUE FALSE FALSE 11503.24502 8987.538038 8602.419997 10658.71382 7976.24071 9346.206277 7753.40261 10654.47091 12649.41795 12245.23062 0.939406155 0.733962333 0.702511881 0.870437981 0.651375295 0.763252777 0.633177345 0.870091487 1.033007735 1 13.57993232 -7.325400436 3.663634138 0.974205464 0.741392726 0.677412564 0.077219748 0.09454954 2.469349822 0.012193658 0.014039216 4.73E-08 7.325400436 -0.232812738 EYIPGQPPLSQS(ph)SDS(ph)SPTR ddPTM_HeLa_Curcumin_4h_R1 2 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 2 0 EYIPGQPPLS(0.265)QS(0.706)S(0.047)DS(0.524)S(0.408)PT(0.052)R;EYIPGQPPLS(0.03)QS(0.969)S(0.068)DS(0.713)S(0.217)PT(0.002)R ; 164.58 2.38E-05 217800000 8016.6 7223.6 8092.6 8300.5 8955.1 7482.4 6864.8 4684.4 7466.4 6994.4 TRUE FALSE FALSE 7382.077651 7847.975796 8392.518875 8266.15473 8848.316281 5930.465896 7057.407812 6112.651996 6647.3546 7237.454879 1.019982546 1.084355748 1.159595329 1.142135581 1.222572911 0.819413177 0.975122875 0.844585852 0.918465774 1 12.82126673 -5.234818269 24.99622233 1.049456768 0.889248858 0.469495309 0.093073375 621.4257537 583494.8513 0.013333584 0.03398392 5.82E-06 5.234818269 -0.160207911 EYIPGQPPLSQSS(ph)DSSPTR ddPTM_HeLa_Curcumin_4h_R1 1 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 0 EYIPGQPPLS(0.001)QS(0.008)S(0.401)DS(0.113)S(0.324)PT(0.152)R 155.24 3.30E-05 801720000 5192.9 5153.6 5171.2 5098.5 5818.1 5723.9 4774.7 4257.9 4817.6 4524.8 TRUE FALSE FALSE 4781.876485 5599.05422 5362.849221 5077.403758 5748.722957 4536.698618 4908.665232 5556.114109 4289.121333 4682.036463 1.021324059 1.195858739 1.145409538 1.084443446 1.227825328 0.968958412 1.048403888 1.186687492 0.916080293 1 12.19292045 -7.407705392 7.753465041 1.00936031 1.117141726 0.399612738 0.077869009 0.237144911 14.56958708 0.012095817 0.013792758 3.91E-08 7.407705392 0.107781415 EYIPGQPPLSQSSDS(ph)SPTR ddPTM_HeLa_Curcumin_4h_R1 2 EYIPGQPPLSQSSDSSPTR 19 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 0 EYIPGQPPLS(0.003)QS(0.081)S(0.025)DS(0.621)S(0.266)PT(0.003)R;EYIPGQPPLSQS(0.001)S(0.014)DS(0.633)S(0.325)PT(0.028)R ; 183.71 1.83E-07 21044900 4674.7 4332.9 4670.4 4800.6 4623.7 4392.7 3197.8 3577.3 4099 3686.7 TRUE FALSE FALSE 4304.692562 4707.416569 4843.489133 4780.736389 4568.565397 3481.604504 3287.521662 4668.002302 3649.349955 3814.812551 1.128415225 1.233983717 1.269653245 1.253203487 1.197585815 0.91265415 0.861778034 1.223651815 0.956626284 1 11.89739645 -3.94338185 20.36418513 1.087912239 3.154297376 0.072976076 0.142187655 636.6388472 273203.9974 0.020346972 11129.87025 0.000113925 3.94338185 2.066385138 EYIPGQPPLSQSSDS(ph)SPTRNSEPAGLETPEAK ddPTM_HeLa_Curcumin_4h_R1 1 EYIPGQPPLSQSSDSSPTRNSEPAGLETPEAK 32 1 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 0 EYIPGQPPLS(0.164)QS(0.146)S(0.13)DS(0.201)S(0.201)PT(0.074)RNS(0.074)EPAGLET(0.011)PEAK 50.58 0.0036977 18043000 4656.6 3315.1 3824.5 4419.2 3116.1 4467.1 3204.7 3561.7 5669 4980.6 TRUE FALSE FALSE 4288.025196 3601.642472 3966.239334 4400.914521 3078.942543 3540.573105 3294.615257 4647.645934 5047.124883 5153.675479 0.832032442 0.698849294 0.769594312 0.853937067 0.597426546 0.686999622 0.639274877 0.901811911 0.979325319 1 12.33138598 -8.186833802 0.508316152 1.00492084 0.714145942 0.55256641 0.089013634 0.448812016 0.264438093 0.05589656 0.028670589 6.50E-09 8.186833802 -0.290774897 EYPS(ph)PPPS(ph)PLR ddPTM_HeLa_Curcumin_4h_R1 2 EYPSPPPSPLR 11 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 2 0 EYPS(1)PPPS(1)PLR;EY(0.001)PS(0.999)PPPS(1)PLR ; 118.76 0.010407 36191000 9926.7 9185.6 8686.5 8769.2 9809.5 10199.6 8134.8 4145.5 9319.3 8410.3 TRUE FALSE FALSE 9140.99122 9979.562334 9008.429331 8732.915374 9692.528119 8084.087987 8363.040594 5409.443866 8296.996106 8702.557299 1.050379895 1.146739055 1.035147374 1.003488409 1.113756312 0.928932463 0.960986559 0.621592445 0.953397469 1 13.08722369 -3.858572663 1.296411245 1.036496953 8.25E-12 0.803247894 0.060616577 0.978508982 0.696283519 0.00802652 1.730075741 0.000138493 3.858572663 -1.036496953 EYPS(ph)PPPS(ph)PLRR ddPTM_HeLa_Curcumin_4h_R1 2 EYPSPPPSPLRR 12 1 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 2 0 EY(0.078)PS(0.922)PPPS(1)PLRR;EY(0.019)PS(0.981)PPPS(1)PLRR ; 85.493 0.0079553 29556900 6036 5282.1 5704.2 5967.9 5992.3 6136.8 5138.6 2772.99 5319.6 5183 TRUE FALSE FALSE 5558.244231 5738.661187 5915.60267 5943.206411 5920.845736 4863.958504 5282.775286 3618.461886 4736.053189 5363.108864 1.036384748 1.070025117 1.103017451 1.108164418 1.103995068 0.906928915 0.98502108 0.674694842 0.883079816 1 12.38885382 -3.7729305 1.23951011 1.036957245 1.03E-19 0.671135636 0.073903579 1.528062388 0.856767865 0.008841814 2.723534105 0.000168682 3.7729305 -1.036957245 S(ph)STPPLHVHVDENTPVHVHIK ddPTM_HeLa_Curcumin_4h_R1 1 SSTPPLHVHVDENTPVHVHIK 21 0 Q5BJF6-9;Q5BJF6-3;Q5BJF6-4 Q5BJF6-9 1 0 S(0.333)S(0.333)T(0.333)PPLHVHVDENT(0.001)PVHVHIK 51.535 0.0070069 6921400 2567 2290.9 2346.9 2540.2 2258.3 2427.1 1185.5 504.36 2786.4 2389.5 TRUE FALSE FALSE 2363.819241 2488.915188 2433.878179 2529.689325 2231.371247 1923.692101 1218.761939 658.1370422 2480.738891 2472.534947 0.95603067 1.006624877 0.984365532 1.023115701 0.902462976 0.778024231 0.492920005 0.266179066 1.00331803 1 11.2717752 -4.657654617 1.258224827 0.984618651 0.168917801 0.990647718 0.023793373 0.053848385 0.113426037 0.003960753 0.0470143 2.20E-05 4.657654617 -0.815700851 down EYQAAYGK ddPTM_HeLa_Curcumin_4h_R1 2 EYQAAYGK 8 0 P12429;D6RA82;D6RFG5;D6RCA8;D6RAZ8 P12429 ANXA3 Annexin A3;Annexin 0 0 ; ; 101.72 0.011843 6421700 4634.3 3894.2 4512.8 4608.3 4705.7 5722.7 3954.5 4241.6 4460.5 4642.7 FALSE FALSE TRUE 4267.490265 4230.797296 4680.048338 4589.232076 4649.587601 4535.747512 4065.452627 5534.844314 3971.19431 4804.033479 0.888314014 0.880676064 0.974191449 0.95528728 0.967850791 0.944154018 0.84625818 1.152124426 0.826637518 1 12.23003049 EYQDLLNVK ddPTM_HeLa_Curcumin_4h_R1 1 EYQDLLNVK 9 0 P08670;B0YJC4;B0YJC5;P17661;E7EMV2;E7ESP9;Q16352;P07197-2;P07196;P07197;P12036-2;P12036 P08670;P12036-2 VIM;DES;NEFM;INA;NEFL;NEFH Vimentin;Desmin;Alpha-internexin;Neurofilament medium polypeptide;Neurofilament light polypeptide;Neurofilament heavy polypeptide 0 0 166.33 1.33E-11 15984000 5660.4 4449.2 4480.3 4861.2 5329.6 6401.6 4698.7 4905.4 5221 5052.6 FALSE FALSE TRUE 5212.373367 4833.769023 4646.343859 4841.085642 5266.048001 5073.835999 4830.532876 6401.033878 4648.269362 5228.177474 0.996977129 0.924561006 0.888711962 0.925960465 1.007243543 0.970478914 0.923942024 1.224333701 0.889080255 1 12.3520924 -4.253957303 24.95130208 0.976420632 1.224333822 0.708544312 0.050273972 379.4139507 1265241.862 0.00670537 0.094305263 5.57E-05 4.253957303 0.24791319 EYTINIHK ddPTM_HeLa_Curcumin_4h_R1 2 EYTINIHK 8 0 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2;B8ZZK4 H7C2W9 RPL31 60S ribosomal protein L31 0 0 ; ; 122.18 0.00070716 11901100 9241.8 7754.5 9509.1 8961.6 10815.2 11879.8 8970.9 7885 9109.7 8566.4 FALSE FALSE TRUE 8510.301778 8424.764427 9861.515611 8924.519274 10686.2358 9415.795567 9222.59931 10289.1002 8110.388701 8864.081762 0.960088366 0.950438483 1.112525344 1.006818248 1.205566024 1.062241507 1.040446101 1.160763233 0.914972235 1 13.11375547 -6.758469393 24.9993221 0.978322649 1.09455243 0.573850742 0.058560141 45.09927366 379611.3896 0.008298516 0.011444971 1.74E-07 6.758469393 0.116229781 EYTINIHK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 EYTINIHKR 9 1 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2;B8ZZK4 H7C2W9 RPL31 60S ribosomal protein L31 0 1 ; EYTINIHK(1)R;EYTINIHK(1)R 109.44 0.00081538 17290600 5361.6 5893.5 4125.4 4314.7 7473.9 11586.6 8379.4 7539.4 12854.6 5022.3 FALSE TRUE FALSE 4937.223702 6402.907879 4278.290953 4296.846915 7384.778624 9183.408552 8614.503412 9838.128353 11444.48254 5196.824551 0.950046255 1.232080825 0.823250989 0.826821624 1.421017499 1.767119221 1.657647536 1.893103809 2.202206834 1 12.34341464 -5.537683507 3.329322708 0.975615106 1.753856958 0.225087 0.406745724 0.052144229 1.205747421 0.017538231 0.039101683 2.90E-06 5.537683507 0.778241852 EYTINIHKR ddPTM_HeLa_Curcumin_4h_R1 2 EYTINIHKR 9 1 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2;B8ZZK4 H7C2W9 RPL31 60S ribosomal protein L31 0 0 ; ; 91.853 0.0015899 19748400 21363.1 17818.6 17380.1 19961.7 16434.3 24309.5 17417.8 18750.5 24765.2 20201 FALSE FALSE TRUE 19672.18809 19358.76039 18024.2218 19879.10377 16238.33171 19267.43568 17906.49659 24467.44113 22048.51952 20902.98325 0.941118684 0.926124284 0.862279876 0.951017543 0.776842784 0.921755304 0.856647895 1.170523884 1.054802526 1 14.35142124 -8.293729441 0.82253435 0.992801133 0.915212213 0.121975727 0.09818876 0.939796442 1.351724072 0.033759701 0.020347093 5.08E-09 8.293729441 -0.07758892 EYVEPELHINDLWR ddPTM_HeLa_Curcumin_4h_R1 1 EYVEPELHINDLWR 14 0 Q7KZ85;Q7KZ85-3 Q7KZ85 SUPT6H Transcription elongation factor SPT6 0 0 91.207 0.0073069 6418500 1564.3 1146.1 1571.9 1328.5 1465.1 1993.8 1702.2 1465.8 1647.1 1340 FALSE FALSE TRUE 1440.484004 1245.163777 1630.155997 1323.003019 1447.629639 1580.263405 1749.959151 1912.715672 1466.417251 1386.5649 1.038886823 0.898020552 1.175679549 0.954158741 1.044040304 1.139696674 1.262082395 1.379463501 1.057590056 1 10.43729943 -4.698784364 1.290594774 1.016338654 1.415896799 0.757894821 0.068205985 0.223840021 0.522554708 0.009076857 0.095448163 2.00E-05 4.698784364 0.399558144 EYVSNDAAQS(ph)DDEEK ddPTM_HeLa_Curcumin_4h_R1 1 EYVSNDAAQSDDEEK 15 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 EYVSNDAAQS(1)DDEEK 168.64 1.10E-10 0 1046.8 986.7 1114.4 942.08 1263.5 1317.2 910.87 1216.9 1364 1067.4 TRUE FALSE FALSE 963.9446754 1071.985951 1155.700644 938.1819226 1248.433588 1043.997872 936.4265607 1587.927208 1214.372613 1104.492071 0.872749295 0.970569169 1.046363913 0.849423864 1.130323722 0.945228943 0.847834571 1.437699057 1.099485134 1 10.10916735 -4.253976756 24.85256463 0.950343824 1.437699309 0.669143157 0.09668021 316.7145033 1054717.315 0.011672933 0.163581495 5.57E-05 4.253976756 0.487355485 EYVSNDAAQS(ph)DDEEKLQSQPTDTDGGR ddPTM_HeLa_Curcumin_4h_R1 4 EYVSNDAAQSDDEEKLQSQPTDTDGGR 27 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 EYVS(0.001)NDAAQS(0.996)DDEEKLQS(0.003)QPTDTDGGR;EY(0.01)VS(0.01)NDAAQS(0.979)DDEEKLQSQPTDTDGGR;EYVS(0.001)NDAAQS(0.99)DDEEKLQS(0.008)QPTDTDGGR;EYVS(0.001)NDAAQS(0.881)DDEEKLQS(0.117)QPT(0.001)DTDGGR ;;; 137.86 1.94E-08 679166000 4409.8 3736.68 4109.76 4451.54 4457.4 4933.83 4210.5 4426.58 4136.38 4077.17 TRUE FALSE FALSE 4060.759677 4059.661969 4262.071321 4433.120707 4404.248416 3910.498042 4328.635298 5776.223865 3682.629463 4218.851354 0.962527318 0.962267126 1.010244487 1.050788552 1.043944915 0.926910601 1.026022236 1.369146097 0.872898605 1 12.04263454 -4.266959392 4.193863454 0.988456244 1.397770657 0.837432399 0.051133727 0.04491412 1.767260983 0.005177691 0.054579358 5.41E-05 4.266959392 0.409314413 EYWMDPEGEMKPGRK ddPTM_HeLa_Curcumin_4h_R1 1 EYWMDPEGEMKPGRK 15 2 P53999 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 0 0 67.019 0.013083 54906000 6251.2 4969.2 4621.8 5537.9 5384.8 6907.5 5326.4 4679.3 6579.9 5427.9 FALSE FALSE TRUE 5756.410924 5398.715506 4793.087974 5514.985637 5320.589777 5474.806636 5475.844449 6105.997029 5858.101432 5616.519121 1.024907207 0.96122089 0.853391197 0.981922347 0.947310899 0.974768628 0.974953406 1.087149691 1.043012817 1 12.45546057 -7.253679485 23.9012448 1.011761737 0.964403753 0.160312571 0.054319471 472.1590457 1454295.448 0.008876323 0.010760689 5.58E-08 7.253679485 -0.047357984 EYWNDPELDEGER ddPTM_HeLa_Curcumin_4h_R1 2 EYWNDPELDEGER 13 0 H0YFD2;F8WFC1;A0A494C108;Q8N9T8 H0YFD2 KRI1 Protein KRI1 homolog 0 0 ; ; 145.81 0.0062845 15195400 2151.4 1909.35 1701.61 2120.6 1754.65 2425.7 1816.3 1564.23 1929.28 1985.56 FALSE FALSE TRUE 1981.11442 2074.385706 1764.673163 2111.825519 1733.726945 1922.582477 1867.26049 2041.156526 1717.642811 2054.558062 0.964253314 1.009650564 0.858906446 1.02787337 0.84384422 0.93576449 0.908838024 0.993477169 0.836015707 1 11.00461239 -7.245878589 0.707467267 0.990946946 0.927859477 0 0.074281208 0.747509709 0.787024776 0.013753376 0.016547227 5.68E-08 7.245878589 -0.063087469 FAAATGATPIAGR ddPTM_HeLa_Curcumin_4h_R1 1 FAAATGATPIAGR 13 0 C9J9K3;A0A0C4DG17;P08865;F8WD59 C9J9K3 RPSA 40S ribosomal protein SA 0 0 160.77 6.06E-05 13493000 1884.5 1713.1 1730.6 1580.6 1588.7 2642.4 1635.5 1622.2 2168.3 1364.6 FALSE FALSE TRUE 1735.339836 1861.172731 1794.737558 1574.059896 1569.75579 2094.336454 1681.387728 2116.801312 1930.442915 1412.019748 1.22897703 1.318092564 1.271042817 1.114757706 1.111709515 1.48322037 1.190767856 1.499130104 1.367150082 1 10.46354455 -13.52287875 0.109246326 0.069574797 1.449853642 0 0.163936038 68.60430616 0.55126897 14.27695359 0.752581742 3.00E-14 13.52287875 1.380278845 FAAYFQQGDMESNGK ddPTM_HeLa_Curcumin_4h_R1 2 FAAYFQQGDMESNGK 15 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;CON__Q3ZBD7 P06744-2 GPI Glucose-6-phosphate isomerase 0 0 ; ; 123.75 0.005448 49633000 6742.3 5300.8 5493.9 5998 5382.3 7615.1 5801.4 6138.6 6901.5 6641.7 FALSE FALSE TRUE 6208.639841 5758.977532 5697.508767 5973.181865 5318.119588 6035.64242 5964.17167 8010.230881 6144.422717 6872.498581 0.903403583 0.83797435 0.829030185 0.869142684 0.773826218 0.878231163 0.867831634 1.165548568 0.89405951 1 12.74661899 -8.627484361 0.888372845 0.991804756 0.881862223 0.005939649 0.103513753 0.709785347 1.133106808 0.04122423 0.020003794 2.36E-09 8.627484361 -0.109942533 FADEHVPGS(ph)PFTVK ddPTM_HeLa_Curcumin_4h_R1 1 FADEHVPGSPFTVK 14 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-5;O75369-4;A0A0C4DGA1 O75369-8 FLNB Filamin-B 1 0 FADEHVPGS(0.999)PFT(0.001)VK 155.98 7.73E-07 0 2820.2 2529.1 2119.8 2519.8 2341.7 5273.2 4295.9 1882.2 2979.3 1908 TRUE FALSE FALSE 2596.978194 2747.704135 2198.361653 2509.373735 2313.776757 4179.478879 4416.431392 2456.074115 2652.478244 1974.302858 1.315389979 1.391733859 1.11348755 1.271017628 1.171946213 2.116939082 2.236957402 1.244020949 1.343501192 1 10.9471276 -5.271844699 24.54254844 1.178804103 1.903070967 0.532405575 0.269717289 259.6539939 612434.2968 0.037501357 0.084740675 5.35E-06 5.271844699 0.724266864 FADLSEAANR ddPTM_HeLa_Curcumin_4h_R1 4 FADLSEAANR 10 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 0 ;;; ;;; 228.31 5.33E-15 146820000 13054.2 10012.1 11273.8 11023.7 11669.1 13768.7 11443.6 10460.4 12062.3 10960.7 FALSE FALSE TRUE 12020.9463 10877.50131 11691.61695 10978.08685 11529.9536 10912.91641 11764.67662 13649.72781 10739.09587 11341.58351 1.059900171 0.959081358 1.030862836 0.967950096 1.0166088 0.962203947 1.037304589 1.203511643 0.946877996 1 13.46933446 -4.27306772 4.205250685 1.014975905 1.216597963 0.700894544 0.039125846 0.084868099 3.357413534 0.005043505 0.05032737 5.33E-05 4.27306772 0.201622058 FADQHVPGS(ph)PFSVK ddPTM_HeLa_Curcumin_4h_R1 2 FADQHVPGSPFSVK 14 0 P21333-2;P21333;Q60FE5 P21333-2;Q60FE5 FLNA Filamin-A 1 0 FADQHVPGS(0.992)PFS(0.008)VK;FADQHVPGS(0.991)PFS(0.009)VK ; 91.475 0.0042698 96169000 10040.3 8500.2 9849.8 10169.7 9035 11689.7 9088.4 7910.9 11172.3 9151.6 TRUE FALSE FALSE 9245.599661 9234.919412 10214.84225 10127.62048 8927.263526 9265.12445 9343.396044 10322.89699 9946.726642 9469.617419 0.976343526 0.975215682 1.078696404 1.069485707 0.942726948 0.978405361 0.986670911 1.09010708 1.050383157 1 13.20909043 FAEAFEAIPR ddPTM_HeLa_Curcumin_4h_R1 2 FAEAFEAIPR 10 0 P50990-2;P50990;P50990-3 P50990-2 CCT8 T-complex protein 1 subunit theta 0 0 ; ; 108.98 0.005668 2525910 1004.8 898.53 983.75 952.07 1143.67 1291.97 955.22 855.8 848.16 873.06 FALSE FALSE TRUE 925.2690197 976.1949294 1020.20864 948.1305866 1130.032482 1024.000858 982.0209024 1116.72948 755.11897 903.39877 1.024208855 1.080580317 1.129300453 1.049515029 1.250867856 1.133498177 1.087029267 1.236142352 0.83586451 1 9.819219139 -6.783161498 0.746708784 1.004451936 1.164990253 0.547702938 0.076352125 0.297150784 0.335534634 0.011652128 0.019098725 1.65E-07 6.783161498 0.160538317 FAGDK(ac)GYLTK ddPTM_HeLa_Curcumin_4h_R1 1 FAGDKGYLTK 10 1 P60903 P60903 S100A10 Protein S100-A10 0 1 FAGDK(1)GYLTK 156.48 1.11E-08 9341100 1686.9 1940.4 1601.9 1551.5 2446.8 5011.5 3384.2 3687.1 4363.8 1456.1 FALSE TRUE FALSE 1553.380085 2108.11953 1661.267823 1545.080304 2417.623508 3972.058409 3479.151544 4811.279817 3885.102058 1506.699367 1.030982105 1.399164011 1.102587457 1.025473521 1.604582548 2.636264737 2.309121263 3.193258007 2.578551597 1 10.55717587 -5.354768325 1.779771758 1.048036801 2.782201978 0.523290931 0.535745669 0.068753995 0.416986657 0.032072741 0.098852336 4.42E-06 5.354768325 1.734165176 FAIQDIS(ph)VEETSAK ddPTM_HeLa_Curcumin_4h_R1 3 FAIQDISVEETSAK 14 0 O43707;G3V2E8;P12814-4;P12814-3;P12814;P12814-2;H9KV75;G3V2N5;A0A494C1A0;P35609-2;P35609;G3V5M4;G3V2W4;G3V2X9;A0A087WSZ2;Q08043;A0A494C166;A0A494C033 O43707;P12814-4 ACTN4;ACTN1;ACTN2;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 1 0 FAIQDIS(1)VEETSAK;FAIQDIS(0.995)VEET(0.004)S(0.001)AK;FAIQDIS(0.999)VEET(0.001)SAK ;; 173.19 0.00019508 158109000 16092.9 13249.5 16284.4 15889.3 19964.4 21496.5 17800.2 16110.4 13494.8 13716 TRUE FALSE FALSE 14819.12998 14394.72774 16887.91419 15823.55429 19726.33757 17037.88358 18299.62571 21022.3868 12014.4542 14192.62998 1.044142629 1.014239627 1.189907312 1.114913466 1.389900082 1.200474021 1.289375241 1.48121855 0.846527685 1 13.79285433 -4.991972216 0.363464348 0.995347199 1.591831156 0.759080493 0.089943088 1.205651615 0.16092732 0.025254775 0.290913886 1.02E-05 4.991972216 0.596483957 FAIQDISVEET(ph)SAK ddPTM_HeLa_Curcumin_4h_R1 1 FAIQDISVEETSAK 14 0 O43707;G3V2E8;P12814-4;P12814-3;P12814;P12814-2;H9KV75;G3V2N5;A0A494C1A0;P35609-2;P35609;G3V5M4;G3V2W4;G3V2X9;A0A087WSZ2;Q08043;A0A494C166;A0A494C033 O43707;P12814-4 ACTN4;ACTN1;ACTN2;ACTN3 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2;Alpha-actinin-3 1 0 FAIQDIS(0.253)VEET(0.689)S(0.058)AK 222.55 6.49E-14 68217000 7024.8 6111.6 7353.5 6486.9 8258.3 8906.8 7238 6464.1 5317.9 5271.9 TRUE FALSE FALSE 6468.779667 6639.859471 7626.027179 6460.058927 8159.825166 7059.42928 7441.0788 8434.974333 4734.539675 5455.098133 1.185822786 1.217184239 1.397963335 1.184224146 1.495816385 1.294097578 1.364059568 1.546255288 0.867911 1 12.41338943 -1.000040402 0.048331235 0.242047305 3.17743985 0.776059653 0.094971792 145.0509794 0.535567076 7.969871996 32.37501835 0.099990698 1.000040402 2.935392545 FAMEPEEFDSDTLR ddPTM_HeLa_Curcumin_4h_R1 1 FAMEPEEFDSDTLR 14 0 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 0 190.36 5.74E-05 4842500 2532.2 1914.1 2224.1 2255.7 2269.9 2328.1 1491.5 1310 1609.7 1998.2 FALSE FALSE TRUE 2331.773698 2079.546275 2306.527103 2246.366511 2242.832925 1845.225817 1533.347476 1709.41297 1433.119937 2067.637301 1.127747936 1.005759702 1.115537576 1.086441278 1.08473228 0.89243206 0.741594029 0.826747016 0.693119599 1 11.01376742 -5.083014097 3.286498615 1.065026258 0.786414405 0.309489425 0.125680384 0.073300601 1.511646341 0.007889876 0.02344596 8.26E-06 5.083014097 -0.278611854 FAQSAPGS(ph)PLSSQPVLITVQR ddPTM_HeLa_Curcumin_4h_R1 2 FAQSAPGSPLSSQPVLITVQR 21 0 Q01167-2;Q01167 Q01167-2 FOXK2 Forkhead box protein K2 1 0 FAQS(0.001)APGS(0.992)PLS(0.008)SQPVLITVQR;FAQSAPGS(0.513)PLS(0.136)S(0.351)QPVLITVQR ; 267.93 1.21E-59 135997000 6884.3 5609.9 5898.1 5745.7 5427.7 9537.1 8107.6 4640.9 6785.2 5499.3 TRUE FALSE FALSE 6339.400391 6094.794759 6116.688774 5721.925816 5362.978222 7558.997955 8335.077436 6055.889046 6040.880536 5690.400266 1.114051753 1.071066089 1.074913625 1.005540129 0.942460631 1.328377197 1.464761185 1.064229011 1.061591497 1 12.47431442 -5.249932775 24.63606241 1.047815246 1.303686365 0.547280596 0.102430289 330.2554405 707086.742 0.0139304 0.035173392 5.62E-06 5.249932775 0.255871119 FARS(ph)DDEQSSADKER ddPTM_HeLa_Curcumin_4h_R1 1 FARSDDEQSSADKER 15 2 A6NGV6;P27540-3;P27540-4;P27540 A6NGV6 ARNT Aryl hydrocarbon receptor nuclear translocator 1 0 FARS(1)DDEQSSADKER 69.805 0.0086685 40627000 3324 2750.7 2851.9 3351.6 2703.7 3081.3 2393.4 1340.4 3926.4 3200.6 TRUE FALSE FALSE 3060.901893 2988.458251 2957.593923 3337.731967 2671.460143 2442.203647 2460.552362 1749.08179 3495.683743 3311.820612 0.924235413 0.902361149 0.893041704 1.007823901 0.806643975 0.737420269 0.74296064 0.52813301 1.055517238 1 11.69340881 -3.682904733 0.454410617 0.968866821 9.78E-15 0.855405747 0.057467355 1.805132738 0.172155096 0.011657647 1.053590449 0.000207537 3.682904733 -0.968866821 FAS(ph)DDEHDEHDENGATGPVK ddPTM_HeLa_Curcumin_4h_R1 4 FASDDEHDEHDENGATGPVK 20 0 P05455 P05455 SSB Lupus La protein 1 0 FAS(1)DDEHDEHDENGATGPVK;FAS(1)DDEHDEHDENGATGPVK;FAS(1)DDEHDEHDENGATGPVK;FAS(1)DDEHDEHDENGATGPVK ;;; 180.64 6.50E-08 1146820000 23181.1 21028.4 22931.5 22559.3 26511.3 24857.8 21925.3 18666.3 20008.5 19706.7 TRUE FALSE FALSE 21346.29147 22846.0012 23781.36156 22465.95559 26195.17006 19702.01207 22540.46491 24357.56894 17813.61761 20391.50636 1.046822687 1.12036849 1.166238587 1.101731044 1.284611818 0.966187182 1.105384983 1.194495812 0.873580269 1 14.31568073 -7.399094377 1.856491806 1.017143351 1.133823849 0.384592179 0.088708188 0.28296028 1.872581923 0.013981398 0.015746751 3.99E-08 7.399094377 0.116680498 FAS(ph)DDEHDEHDENGATGPVKR ddPTM_HeLa_Curcumin_4h_R1 2 FASDDEHDEHDENGATGPVKR 21 1 P05455 P05455 SSB Lupus La protein 1 0 FAS(1)DDEHDEHDENGATGPVKR;FAS(1)DDEHDEHDENGATGPVKR ; 80.314 0.0003054 63337000 8365.4 6610.8 7018.3 7823.2 8373.3 8503.1 6848.3 6199.1 8915.6 7207.7 TRUE FALSE FALSE 7703.269763 7182.208095 7278.404372 7790.829671 8273.453866 6739.46121 7040.444867 8089.177053 7937.580986 7458.167039 1.032863668 0.962999093 0.975897206 1.044603806 1.109314638 0.903635059 0.943991309 1.084606581 1.064280398 1 12.86460539 -5.240895409 24.98472306 1.016413283 0.974069039 0.111104102 0.059021553 1481.847002 1802156.077 0.007810167 0.019889195 5.74E-06 5.240895409 -0.042344244 SRT(ph)AS(ph)GSSVTSLDGTR ddPTM_HeLa_Curcumin_4h_R1 2 SRTASGSSVTSLDGTR 16 1 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 2 0 S(0.294)RT(0.706)AS(0.578)GS(0.248)S(0.165)VT(0.005)S(0.003)LDGTR;S(0.128)RT(0.896)AS(0.883)GS(0.053)S(0.038)VT(0.003)S(0.001)LDGTR ; 165.24 0.00088847 188322000 11899.3 10402.7 9373.8 9944 10417.1 12731 13006.7 20412.3 11785.1 11039.5 TRUE FALSE FALSE 10957.45785 11301.86303 9721.201274 9902.854363 10292.88289 10090.44709 13371.633 26635.9163 10492.30401 11423.1218 0.959234966 0.989384796 0.851010909 0.866913138 0.901056915 0.883335332 1.170576067 2.331754556 0.918514588 1 13.47966936 -4.262412375 3.075486254 0.953289421 2.546219275 0.982448618 0.056182063 0.037397928 0.527455081 0.009093489 0.144100021 5.46E-05 4.262412375 1.592929854 up FCLDNGAK ddPTM_HeLa_Curcumin_4h_R1 1 FCLDNGAK 8 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 0 117.04 0.0030467 18210000 6435.5 4986.7 5910.6 5775 5563.4 8139.2 6172.8 6750.2 6018.8 5306.6 FALSE FALSE TRUE 5926.123384 5417.728128 6129.652035 5751.10458 5497.060089 6451.038172 6345.992155 8808.304906 5358.552698 5491.003955 1.079242236 0.986655295 1.116308071 1.047368501 1.001102919 1.174837648 1.155707081 1.604133776 0.975878499 1 12.42285424 FDAGELITQR ddPTM_HeLa_Curcumin_4h_R1 2 FDAGELITQR 10 0 P35232;C9JZ20;E7ESE2;E9PCW0;C9JW96 P35232 PHB Prohibitin 0 0 ; ; 102.06 0.008944 5267200 2315.9 2068.21 2268.28 2164.6 2399.2 3100.9 2055.6 1849.7 2791.1 2273.3 FALSE FALSE TRUE 2132.594071 2246.976857 2352.344452 2155.643459 2370.591107 2457.738386 2113.274604 2413.665015 2484.923313 2352.297006 0.906600683 0.955226679 1.00002017 0.916399355 1.007777122 1.044824858 0.89838766 1.026088546 1.056381616 1 11.19985451 -5.734259483 24.96313113 0.956020771 0.991031932 0 0.055624874 414.1898386 380406.6964 0.007320335 0.014637991 1.84E-06 5.734259483 0.035011162 FDASFFGVHPK ddPTM_HeLa_Curcumin_4h_R1 1 FDASFFGVHPK 11 0 P49327;A0A0U1RQF0;A0A0U1RRG3 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 0 109.79 0.0013248 1353200 3015.4 2417 3912.4 2734.7 2618 3156.4 2030.6 1685.4 1987.8 1438.2 FALSE FALSE TRUE 2776.727908 2625.91471 4057.396986 2723.384536 2586.78206 2501.72706 2087.573171 2199.270701 1769.743313 1488.177343 1.865858207 1.764517329 2.726420346 1.830013438 1.738221639 1.681067832 1.402771774 1.477828373 1.189201893 1 10.53933074 -9.117828757 0.884691609 1.001092338 1.817957966 0.406336761 0.343026141 0.458940492 0.650397828 0.238808722 0.070196565 7.62E-10 9.117828757 0.816865628 FDDAVVQSDMK ddPTM_HeLa_Curcumin_4h_R1 1 FDDAVVQSDMK 11 0 P11142;E9PKE3;E9PNE6;P11142-2;E9PN89;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 123.8 0.0016067 1337200 598.58 632.02 571.72 666.22 651.82 603.01 681.38 535.37 641.85 714.72 FALSE FALSE TRUE 551.2017614 686.6489926 592.9084461 663.4633582 644.0474722 477.9389287 700.497689 698.6018485 571.4406608 739.5564668 0.745313963 0.928460535 0.801708149 0.897109806 0.870856386 0.64625076 0.947186213 0.94462273 0.77268023 1 9.530516494 -9.562102279 1.333893238 1.00006844 0.834681837 0 0.114661031 0.435822117 1.388742474 0.064756773 0.015215942 2.74E-10 9.562102279 -0.165386603 FDDDKVSIVTPEDILR ddPTM_HeLa_Curcumin_4h_R1 2 FDDDKVSIVTPEDILR 16 1 A6NJA2;P54578-2;P54578-3;P54578 A6NJA2 USP14 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 14 0 0 ; ; 123.72 0.00061122 17905200 2086.83 2129.11 1921.12 1658.84 2290.02 2390.49 2126.05 2110.9 2300.46 2170.6 FALSE FALSE TRUE 1921.655203 2313.140781 1992.318397 1651.97616 2262.713007 1894.675428 2185.701241 2754.503693 2048.105293 2246.028188 0.85557929 1.029880566 0.887040691 0.735509985 1.007428588 0.843567074 0.97314061 1.226388746 0.911878713 1 11.13316032 -4.284191874 3.602303283 0.920556532 1.25425831 0.553898529 0.084664838 0.157065838 3.66934276 0.012218728 0.135751703 5.20E-05 4.284191874 0.333701778 FDDGAGGDNEVQR ddPTM_HeLa_Curcumin_4h_R1 1 FDDGAGGDNEVQR 13 0 P35998;P35998-2 P35998 PSMC2 26S protease regulatory subunit 7 0 0 114.71 0.0052063 0 2617.5 2538 2602.8 2946.2 2983.8 3117.7 2342.1 1499.7 2766.6 2224.4 FALSE FALSE TRUE 2410.322113 2757.373411 2699.262058 2934.009405 2948.220134 2471.053876 2407.813023 1956.951626 2463.110902 2301.697734 1.047193155 1.197973726 1.172726556 1.274715338 1.280889358 1.073578793 1.046103051 0.850220946 1.070127873 1 11.16848267 -7.443589424 4.982880269 1.020176161 1.135946568 0.099461312 0.119203858 0.315354451 13.39462722 0.021747774 0.024499042 3.60E-08 7.443589424 0.115770407 DAQNS(ph)SDSSFEKNVEITEQLANGR ddPTM_HeLa_Curcumin_4h_R1 1 DAQNSSDSSFEKNVEITEQLANGR 24 1 Q6PL18 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 0 DAQNS(0.25)S(0.25)DS(0.25)S(0.25)FEKNVEITEQLANGR 47.991 0.013915 4092400 535.29 562.28 614.9 562.28 667.93 728.76 326.07 151.64 594.71 670.59 TRUE FALSE FALSE 492.9212317 610.8809777 637.6887349 559.9534343 659.965371 577.6069612 335.2186466 197.8743379 529.4718009 693.8929526 0.710370713 0.88036775 0.919001602 0.806973802 0.951105453 0.832415085 0.483098503 0.28516551 0.763045364 1 9.438569304 -4.648320628 2.728626731 0.868242164 0.304309324 0.846837435 0.082636895 0.097747699 1.36906699 0.01551152 0.084162472 2.25E-05 4.648320628 -0.563932841 down FDHS(ph)PTPSASSR ddPTM_HeLa_Curcumin_4h_R1 1 FDHSPTPSASSR 12 0 O15516 O15516 CLOCK Circadian locomoter output cycles protein kaput 1 0 FDHS(0.999)PT(0.001)PSASSR 82.483 0.010539 4552100 1352 1175.2 1089.9 1292.5 1189.9 1432.1 1196.5 1089.5 1500.3 1181.6 TRUE FALSE FALSE 1244.987773 1276.779051 1130.292653 1287.151977 1175.71122 1135.066317 1230.07057 1421.683535 1335.720844 1222.660512 1.018261211 1.044262932 0.924453388 1.052746829 0.961600713 0.928357713 1.006060601 1.162778646 1.092470748 1 10.25580816 -4.263864808 6.242430398 0.999737797 1.166422665 0.468343278 0.050949628 0.063734206 13.36586978 0.005508102 0.045065911 5.45E-05 4.263864808 0.166684867 FDIYDPFHPTDEAYS(ph)PPPAPEQK ddPTM_HeLa_Curcumin_4h_R1 4 FDIYDPFHPTDEAYSPPPAPEQK 23 0 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 1 0 FDIYDPFHPTDEAY(0.007)S(0.993)PPPAPEQK;FDIYDPFHPTDEAY(0.441)S(0.559)PPPAPEQK;FDIYDPFHPTDEAY(0.15)S(0.85)PPPAPEQK;FDIYDPFHPT(0.003)DEAY(0.383)S(0.614)PPPAPEQK ;;; 150.22 1.43E-06 728182000 31831.9 27951.1 26794.1 27587.4 30282 41295.7 28092.5 20060.5 33567.1 28157.6 TRUE FALSE FALSE 29312.37153 30367.06854 27787.11292 27473.25065 29920.90693 32730.50632 28880.69994 26176.8541 29884.87311 29136.0745 1.006050816 1.042249824 0.953701327 0.942929036 1.026936794 1.123367059 0.991235107 0.898434485 1.025700051 1 14.8305189 FDLLWLIQDRPDRDNDLR ddPTM_HeLa_Curcumin_4h_R1 1 FDLLWLIQDRPDRDNDLR 18 2 P33993;P33993-3 P33993 MCM7 DNA replication licensing factor MCM7 0 0 75.574 0.0036406 33461000 2501.8 1596.8 1841.2 2164.2 1980.8 2604.8 2013.2 1921 2476.4 2211.5 FALSE FALSE TRUE 2303.77989 1734.820277 1909.436492 2155.245114 1957.180254 2064.535118 2069.684974 2506.704057 2204.745116 2288.34946 1.006743039 0.758109855 0.834416476 0.941833907 0.855280318 0.902193985 0.904444452 1.095420127 0.96346522 1 11.16009167 -7.404616336 21.66761622 1.003199368 0.895642555 0.198894183 0.082499615 6.577325658 1184.099067 0.013587892 0.015538223 3.94E-08 7.404616336 -0.107556813 FDLQYPEEMWRNTVVQKGRK ddPTM_HeLa_Curcumin_4h_R1 1 FDLQYPEEMWRNTVVQKGRK 20 3 B4E159 B4E159 ZNF721 0 0 56.039 0.0090545 0 530.43 651.46 592.8 546.63 624.79 590.01 622.7 374.5 647.32 612.41 FALSE FALSE TRUE 488.4459058 707.7692996 614.7696895 544.3681899 617.3397873 467.6352752 640.1712861 488.683326 576.3106155 633.6912019 0.770794836 1.116899363 0.9701408 0.859043314 0.974196557 0.737954502 1.010225934 0.771169498 0.90945024 1 9.307636175 FDQLFDDES(ph)DPFEVLK ddPTM_HeLa_Curcumin_4h_R1 1 FDQLFDDESDPFEVLK 16 0 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 0 FDQLFDDES(1)DPFEVLK 107.57 0.0026951 0 64.248 0 131.14 64.285 129.64 219.1 168.33 67.49 183.93 136.4 TRUE FALSE FALSE 59.16270301 0 136.0001638 64.0190057 128.0941277 173.6561902 173.0528868 88.06739031 163.7533392 141.1398898 0.419177761 0 0.963584171 0.453585487 0.907568568 1.23038349 1.226108983 0.623972361 1.160220115 1 7.140981979 -5.552478448 8.098269078 0.662097041 1.050636699 0.179785202 0.352029131 0.260021349 60.69485579 0.051692662 0.104318079 2.80E-06 5.552478448 0.388539658 FDQLLAEEK ddPTM_HeLa_Curcumin_4h_R1 1 FDQLLAEEK 9 0 P35579;P35579-2;P35580;P35580-5;P35580-2;P35580-3;P35580-4;P35749-4;P35749-3;P35749;P35749-2;Q7Z406;Q7Z406-6;Q7Z406-2;A0A0C4DFM8;A1L2Z2 P35579;P35580;P35749-4;Q7Z406 MYH9;MYH10;MYH11;MYH14 Myosin-9;Myosin-10;Myosin-11;Myosin-14 0 0 115.78 0.0017347 726050 437.11 396.1 401.19 382.49 297.46 355.1 198.18 377.83 355.28 311.16 FALSE FALSE TRUE 402.5122823 430.337119 416.0584543 380.9073577 293.9129838 281.4482572 203.7403974 493.0286277 316.3066729 321.9727868 1.250143797 1.336563637 1.29221621 1.183042087 0.912850389 0.874136786 0.632787632 1.531274219 0.982401885 1 8.330794947 -5.764185719 24.9999806 1.157642383 0.954290806 0.121286311 0.236495474 106.0869521 965724.9497 0.033840452 0.063392643 1.72E-06 5.764185719 -0.203351577 FDREVDIGIPDATGR ddPTM_HeLa_Curcumin_4h_R1 1 FDREVDIGIPDATGR 15 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 98.676 0.0038076 8219000 4003.2 3439.6 3483.4 3846.1 3839.5 5102.5 3431.7 3950.4 4493.6 3571.7 FALSE FALSE TRUE 3686.342496 3736.903697 3612.497868 3830.185857 3793.71647 4044.183983 3527.984266 5154.858775 4000.663322 3695.816309 0.997436611 1.01111727 0.977456011 1.036357204 1.026489455 1.094260008 0.95458864 1.394782192 1.082484352 1 11.85167734 -4.256748517 24.99998353 1.00667241 1.394782349 0.87145243 0.042905529 91.89586353 489742.952 0.004659991 0.050134247 5.54E-05 4.256748517 0.388109939 FDSPDLLLEAGDPATS(ph)PCR ddPTM_HeLa_Curcumin_4h_R1 2 FDSPDLLLEAGDPATSPCR 19 0 A0A096LNM2;Q969U6-2;Q969U6 A0A096LNM2 FBXW5 F-box/WD repeat-containing protein 5 1 0 FDSPDLLLEAGDPAT(0.052)S(0.948)PCR;FDSPDLLLEAGDPAT(0.348)S(0.652)PCR ; 122.97 0.00010909 23484200 3405.6 2581.97 2873.1 2883.79 2816.3 3271 1979.77 1763.98 3208.8 2745.5 TRUE FALSE FALSE 3136.043166 2805.143982 2979.579613 2871.857641 2782.717462 2592.557728 2035.317018 2301.809382 2856.802668 2840.905921 1.103888426 0.987411783 1.048813194 1.010895018 0.97951764 0.912581339 0.71643239 0.810237807 1.005595661 1 11.47213534 -5.103525635 1.551751951 1.042814104 0.754452059 0.835986699 0.044351937 0.121100492 0.53266608 0.00736182 0.032267887 7.88E-06 5.103525635 -0.288362045 FDSSLLS(ph)SDDETK ddPTM_HeLa_Curcumin_4h_R1 2 FDSSLLSSDDETK 13 0 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 0 FDSSLLS(0.5)S(0.5)DDETK;FDSSLLS(0.844)S(0.156)DDETK ; 248.36 1.05E-27 61876000 10349.9 8569.9 8939.1 9500.2 9365.4 11484.7 9341.3 9250 10441 8218.5 TRUE FALSE FALSE 9530.694494 9310.643969 9270.39091 9460.89069 9253.723722 9102.643761 9603.391737 12070.28242 9295.648422 8504.092263 1.120718614 1.094842775 1.090109399 1.112510353 1.088149497 1.070383937 1.129267115 1.41934989 1.093079442 1 13.05394153 -4.237212795 2.594298013 1.07012111 1.504766287 0.897992557 0.033474066 0.165603487 1.347551557 0.006928469 0.160251724 5.79E-05 4.237212795 0.434645177 FDTFSSLVPEDS(ph)PHVGHR ddPTM_HeLa_Curcumin_4h_R1 2 FDTFSSLVPEDSPHVGHR 18 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 FDTFSSLVPEDS(1)PHVGHR;FDTFSSLVPEDS(1)PHVGHR ; 103.92 0.00051523 6225700 2785.1 2652.8 2300.3 2684.1 2622.9 5171.1 4549.6 1429.85 2968.6 2034.53 TRUE FALSE FALSE 2564.656396 2882.096211 2385.551142 2672.993905 2591.623631 4098.55557 4677.249531 1865.804683 2642.952007 2105.229766 1.218231111 1.369017415 1.133154765 1.269692244 1.23104075 1.946844775 2.221728767 0.886271282 1.255422116 1 11.03976198 -5.370834645 5.366486382 1.144861293 1.735763199 0.283216102 0.333090102 0.164314248 6.775254754 0.044807441 0.101953172 4.26E-06 5.370834645 0.590901906 FDVPGDENAEMDAR ddPTM_HeLa_Curcumin_4h_R1 1 FDVPGDENAEMDAR 14 0 P46940;H0YLE8 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 0 112.83 0.0020306 0 1070.9 816.38 847.96 953.04 985.4 785.33 765.74 701.63 956.54 673.49 FALSE FALSE TRUE 986.137135 886.9442495 879.3861435 949.096573 973.6497486 622.4437055 787.2246035 915.5537571 851.6099551 696.8937274 1.415046651 1.272710909 1.261865488 1.361895703 1.397128013 0.893168759 1.129619299 1.313763808 1.222008352 1 9.444794859 -3.655257983 5.435541702 1.210348057 9.060044259 0.030056761 0.160569268 6386.397063 1656.61663 0.027166086 608975.8969 0.000221178 3.655257983 7.849696202 FDVSSTSVFK ddPTM_HeLa_Curcumin_4h_R1 1 FDVSSTSVFK 10 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 0 0 112.84 0.0045032 765380 369.27 258.11 389.84 389.51 379.58 327.6 234.33 245.6 402.76 298.55 FALSE FALSE TRUE 340.0418898 280.4198783 404.2878133 387.8983108 375.0537564 259.6520672 240.9046691 320.4823094 358.5782357 308.9245903 1.100727817 0.907729223 1.30869418 1.255640771 1.214062487 0.840503072 0.779817071 1.037412752 1.160730634 1 8.271110903 -5.243975049 24.71807354 1.08352971 0.875301552 0.385073916 0.133456781 669.9069788 948147.98 0.019666506 0.050010478 5.70E-06 5.243975049 -0.208228158 FEALNLS(ph)FK ddPTM_HeLa_Curcumin_4h_R1 1 FEALNLSFK 9 0 P14859-6;P14859-2;P14859;P14859-3;P14859-5;P14859-4;A0A0C4DG88;A0A0A0MT46;Q9UKI9;Q9UKI9-2;H0YLC5;Q9UKI9-3;P09086;U3KQ96;P09086-3;U3KQN1;H0YNW1;H0YLL6;P09086-4;B5ME60;P09086-5;H0YKT2;P09086-2 P14859-6 POU2F1;POU2F3;POU2F2 "POU domain, class 2, transcription factor 1;POU domain protein;POU domain, class 2, transcription factor 3;POU domain, class 2, transcription factor 2" 1 0 FEALNLS(1)FK 100.38 0.01291 7657100 1135.7 1240.2 1107.7 1358.2 1452.7 2358.4 2191.9 1165.4 1628.2 1207.7 TRUE FALSE FALSE 1045.808147 1347.397362 1148.752336 1352.580128 1435.377501 1869.241255 2253.398815 1520.725095 1449.590534 1249.667485 0.836869134 1.078204705 0.9192464 1.082352021 1.148607544 1.495790902 1.803198724 1.216903787 1.159980996 1 10.28732855 -5.480840989 1.821757393 0.938826279 1.545814115 0.624120799 0.165481015 0.125049535 0.812217791 0.021744809 0.059868592 3.30E-06 5.480840989 0.606987836 FEDENFILK ddPTM_HeLa_Curcumin_4h_R1 4 FEDENFILK 9 0 P62937;F8WE65;C9J5S7;P62937-2 P62937 PPIA "Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase" 0 0 ;;; ;;; 209.19 2.00E-27 230824400 11312.6 9340.5 10978.5 9786.8 11638.1 12467.8 11783.6 10937.5 9456.34 7700.57 FALSE FALSE TRUE 10417.19577 10147.8512 11385.37287 9746.304815 11499.32326 9881.837739 12114.2161 14272.2934 8419.003161 7968.164234 1.307352041 1.273549453 1.428857706 1.223155614 1.443158414 1.240164917 1.52032711 1.791164562 1.056580024 1 12.96003167 -1 0.055196008 0.342915661 3.34170832 0.696980861 0.12038785 154.7261446 0.648016364 7.800596706 38.46304358 0.1 1 2.998792658 FEDLHDMTSFTHLKK ddPTM_HeLa_Curcumin_4h_R1 1 FEDLHDMTSFTHLKK 15 1 Q53TS8;Q53TS8-4 Q53TS8 ALS2CR11 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein 0 0 40.552 0.019921 49276000 4208.7 3101.6 3799.7 3844.9 3141.9 3540.3 3592.6 1033.8 4634.4 3987.3 FALSE FALSE TRUE 3875.576954 3369.688484 3940.520225 3828.990823 3104.434895 2806.001873 3693.398687 1349.000861 4126.017915 4125.858378 0.939338339 0.816724224 0.955078886 0.928047081 0.752433702 0.680101355 0.895183099 0.326962474 1.000038667 1 12.01047859 -3.859540866 0.452572541 0.970685706 3.65E-21 0.661398242 0.113578421 2.833130113 0.30146962 0.023810229 1.590421127 0.000138184 3.859540866 -0.970685706 FEDPRDAEDAIYGR ddPTM_HeLa_Curcumin_4h_R1 1 FEDPRDAEDAIYGR 14 1 Q13242;H0YIB4;S4R3G0 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 0 0 107.93 0.0028343 17619000 1133.4 702.86 671.12 794.19 695.59 1508.2 1088.8 1302 1316 930.38 FALSE FALSE TRUE 1043.690194 763.6120865 695.9922976 790.9038522 687.2955436 1195.382319 1119.348798 1698.973806 1171.638092 962.7106357 1.084116198 0.793189623 0.722950668 0.821538501 0.713917057 1.241683923 1.162705341 1.764781382 1.217019994 1 9.910958419 -4.060903867 1.343529518 0.967452841 2.40892113 0.66771636 0.175783966 0.990370167 1.098275108 0.026207366 2.198709062 8.69E-05 4.060903867 1.44146829 FEDYLNAESR ddPTM_HeLa_Curcumin_4h_R1 1 FEDYLNAESR 10 0 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;A0A0U1RRH9;A0A0U1RRE1;A0A5F9ZGZ7 G3V1Q4 7-Sep Septin-7 0 0 173.24 0.0037034 15422000 4297.4 3276.9 3711.8 3637.1 4397.2 3819.4 3373.2 3502.6 3662.5 3069.4 FALSE FALSE TRUE 3957.256255 3560.140634 3849.362573 3622.050644 4344.766262 3027.213386 3467.842913 4570.526616 3260.732913 3176.061422 1.24596339 1.120929403 1.211992485 1.140422102 1.367972997 0.953134397 1.09186897 1.439054857 1.026659274 1 11.6330231 -9.401478391 1.009401477 0.994554462 1.191542564 0.237607105 0.13066428 0.663104504 1.153858672 0.097890877 0.022302106 3.97E-10 9.401478391 0.196988102 FEEESKEPVADEEEEDS(ph)DDDVEPITEFR ddPTM_HeLa_Curcumin_4h_R1 12 FEEESKEPVADEEEEDSDDDVEPITEFR 28 1 P54105;E9PJF4 P54105 CLNS1A Methylosome subunit pICln 1 0 FEEESKEPVADEEEEDS(0.991)DDDVEPIT(0.009)EFR;FEEESKEPVADEEEEDS(1)DDDVEPITEFR;FEEESKEPVADEEEEDS(1)DDDVEPITEFR;FEEESKEPVADEEEEDS(1)DDDVEPITEFR;FEEESKEPVADEEEEDS(1)DDDVEPITEFR;FEEESKEPVADEEEEDS(1)DDDVEPITEFR;FEEESKEPVADEEEEDS(0.999)DDDVEPITEFR;FEEESKEPVADEEEEDS(0.997)DDDVEPIT(0.003)EFR;FEEESKEPVADEEEEDS(1)DDDVEPITEFR;FEEESKEPVADEEEEDS(1)DDDVEPITEFR;FEEESKEPVADEEEEDS(1)DDDVEPITEFR;FEEESKEPVADEEEEDS(1)DDDVEPITEFR ;;;;;;;;;;; 143.06 7.95E-11 3709291000 36991.86 25122.27 30429.77 30696.83 35179.85 41257.6 30140.51 31246.82 35078.06 26853.43 TRUE FALSE FALSE 34063.91525 27293.72708 31557.52404 30569.81465 34760.35327 32700.30869 30986.17159 40773.83158 31230.08458 27786.58469 1.225912275 0.982262749 1.13571079 1.100164521 1.250976097 1.176837998 1.115148621 1.467392701 1.123926705 1 14.7621009 -1 0.021367524 3.54E-09 2.698605249 0.30748219 0.109145794 2259.041688 3.756193539 173.0742372 323.480768 0.1 1 2.698605246 FEEESKEPVADEEEEDSDDDVEPITEFR ddPTM_HeLa_Curcumin_4h_R1 2 FEEESKEPVADEEEEDSDDDVEPITEFR 28 1 P54105;E9PJF4 P54105 CLNS1A Methylosome subunit pICln 0 0 ; ; 201.29 3.16E-24 32484000 5053.4 3620.6 4230.8 5025.7 4830.9 5824.5 3722.8 4150.4 5133.5 4170.7 FALSE FALSE TRUE 4653.418058 3933.548531 4387.59717 5004.904985 4773.294673 4616.433044 3827.251749 5415.837854 4570.367893 4315.631515 1.078270478 0.911465337 1.016675579 1.159715552 1.106047784 1.069700466 0.886834693 1.25493519 1.059026443 1 12.07535597 FEELNADLFR ddPTM_HeLa_Curcumin_4h_R1 4 FEELNADLFR 10 0 P11142;E9PKE3;E9PNE6;P11142-2;E9PN89;A8K7Q2;P54652 P11142;P54652 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 0 ;;; ;;; 201.61 1.04E-05 135588300 13112.9 10167.3 11575.5 11500.7 13049.2 15001.1 10967.3 10627.9 12620.9 10816.8 FALSE FALSE TRUE 12075.00013 11046.11611 12004.49821 11453.11315 12893.59681 11889.70276 11275.01292 13868.29779 11236.41885 11192.68299 1.078829815 0.986905116 1.072530886 1.023267893 1.151966586 1.062274592 1.007355692 1.23905035 1.00390754 1 13.45026829 FEETTADGR ddPTM_HeLa_Curcumin_4h_R1 1 FEETTADGR 9 0 I6L8B7;Q01469 I6L8B7 FABP5 "Fatty acid-binding protein, epidermal" 0 0 89.296 0.019439 0 1515.6 1449.3 1605 1833.4 1856.6 2467.4 1582.5 1432.3 1658.4 1520.9 FALSE FALSE TRUE 1395.638661 1574.571034 1664.482712 1825.813877 1834.461258 1955.633427 1626.900691 1869.001677 1476.477669 1573.751162 0.886822958 1.000520967 1.057653047 1.160166817 1.165661575 1.242657336 1.033772511 1.187609402 0.938190042 1 10.61999173 -6.606961123 2.040436683 0.947027541 1.156468045 0.743892334 0.056119356 0.130364187 1.101142434 0.010388865 0.015772297 2.47E-07 6.606961123 0.209440503 FEEVEEEPEVIPGPPS(ph)ESPGMLTK ddPTM_HeLa_Curcumin_4h_R1 1 FEEVEEEPEVIPGPPSESPGMLTK 24 0 O43395 O43395 PRPF3 U4/U6 small nuclear ribonucleoprotein Prp3 1 0 FEEVEEEPEVIPGPPS(0.481)ES(0.481)PGMLT(0.038)K 47.554 0.020246 8097900 3273.7 2703.6 2804.6 3620.3 3588.4 6061.2 4915.9 2901.7 4034.3 3023 TRUE FALSE FALSE 3014.583191 2937.287137 2908.540943 3605.320158 3545.610674 4804.038796 5053.826924 3786.414972 3591.747383 3128.049025 0.963726325 0.939015697 0.929825882 1.152577894 1.133489483 1.535793959 1.615648247 1.210471748 1.14823884 1 11.61104741 -5.550305107 1.88764342 0.979510952 1.46923869 0.692854653 0.12615176 0.108388237 0.766835052 0.015978435 0.041196553 2.82E-06 5.550305107 0.489727738 FEGLS(ph)PLQR ddPTM_HeLa_Curcumin_4h_R1 1 FEGLSPLQR 9 0 Q9Y3E2 Q9Y3E2 BOLA1 BolA-like protein 1 1 0 FEGLS(1)PLQR 95.483 0.015778 5238700 3141.4 2526.5 2439 2832 2913.4 4260.8 3789.7 1742.1 3091.7 2499.9 TRUE FALSE FALSE 2892.754875 2744.879402 2529.391486 2820.281934 2878.659608 3377.062051 3896.028783 2273.25827 2752.548245 2586.771339 1.118287818 1.061121778 0.977817965 1.090271062 1.112838837 1.305512397 1.506135747 0.878801399 1.064086417 1 11.33693682 -5.445904208 3.667798615 1.054175496 1.256252478 0.215296815 0.149050613 0.231040462 5.915261115 0.020083279 0.04657243 3.58E-06 5.445904208 0.202076982 FEIGEGENLDLPYGLER ddPTM_HeLa_Curcumin_4h_R1 3 FEIGEGENLDLPYGLER 17 0 Q02790 Q02790 FKBP4 "Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed" 0 0 ;; ;; 247.11 5.24E-30 19970000 4612.7 3773.79 3822.3 4304.2 4016.7 5162.2 4317.9 4073.8 4137.8 3642.2 FALSE FALSE TRUE 4247.599928 4099.979592 3963.9578 4286.390361 3968.803476 4091.50153 4439.048653 5315.882867 3683.893692 3768.766179 1.127053186 1.087883779 1.051791916 1.137345794 1.053077662 1.08563422 1.177851966 1.410510128 0.977480034 1 11.87987658 -4.203794317 1.640042769 1.067825524 1.570096819 0.834341686 0.046994239 0.370546077 0.843946673 0.007423008 0.306825658 6.25E-05 4.203794317 0.502271295 FEK(ac)EAAEMGK ddPTM_HeLa_Curcumin_4h_R1 2 FEKEAAEMGK 10 1 A0A2U3TZH3;Q05639;A0A2R8Y488;A0A2R8Y660;A0A2R8YDN5;Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A6PW80;Q5JR01 A0A2U3TZH3;Q5VTE0 EEF1A2;EEF1A1P5;EEF1A1 Elongation factor 1-alpha 2;Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 1 ; FEK(1)EAAEMGK;FEK(1)EAAEMGK 158.41 8.57E-09 10661000 3514.4 3923.1 2934.7 3627.8 4939.2 6549.4 4791.6 4522.1 6720 3485.7 FALSE TRUE FALSE 3236.231532 4262.195283 3043.462564 3612.789125 4880.303266 5190.980613 4926.0394 5900.867473 5982.832813 3606.827816 0.897251462 1.1817019 0.843805892 1.001652785 1.353073536 1.439209432 1.365753968 1.63602694 1.658751989 1 11.81651484 -5.700166388 3.028882609 0.961422521 1.462748959 0.249860999 0.243847918 0.070942269 1.319386806 0.014980676 0.031379862 1.99E-06 5.700166388 0.501326439 FEKEAAEMGK ddPTM_HeLa_Curcumin_4h_R1 2 FEKEAAEMGK 10 1 A0A2U3TZH3;Q05639;A0A2R8Y488;A0A2R8Y660;A0A2R8YDN5;Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A6PW80;Q5JR01 A0A2U3TZH3;Q5VTE0 EEF1A2;EEF1A1P5;EEF1A1 Elongation factor 1-alpha 2;Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 0 ; ; 115.91 1.66E-06 5480500 7337.9 6022.9 5979.7 6400.3 5540.4 7452.8 5311.2 5030.1 8108.2 6971.1 FALSE FALSE TRUE 6757.097472 6543.492638 6201.312942 6373.817254 5474.334349 5907.00527 5460.217978 6563.754334 7218.750746 7213.345206 0.936749494 0.907137043 0.85970001 0.883614616 0.758917561 0.818899568 0.756960581 0.909945961 1.00074938 1 12.81645275 -7.002707018 0.634321476 0.986416976 0.807003455 0.70312617 0.044826362 0.251094334 0.214073234 0.011532403 0.016630012 9.94E-08 7.002707018 -0.179413521 SGTAETEPVEQDSS(ph)QPS(ph)LPLVR ddPTM_HeLa_Curcumin_4h_R1 1 SGTAETEPVEQDSSQPSLPLVR 22 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0;H7C3N7 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 SGTAETEPVEQDS(0.522)S(0.583)QPS(0.895)LPLVR 72.474 0.0043079 3234900 1035.7 844.33 819.31 1064.3 1061.4 1101.7 618.63 346.31 910.17 893.35 TRUE FALSE FALSE 953.7232521 917.3101229 849.6743493 1059.896209 1048.743498 873.1950013 635.9870928 451.8983248 810.3266281 924.393846 1.031728258 0.992336899 0.919169197 1.146585098 1.134520208 0.944613603 0.688004464 0.48885908 0.876603227 1 9.852363845 -4.644813106 2.333451606 1.023890073 0.499085911 0.825033578 0.079762902 0.078079118 0.771973551 0.009519558 0.059757545 2.27E-05 4.644813106 -0.524804162 down FEPES(ph)PGFESR ddPTM_HeLa_Curcumin_4h_R1 4 FEPESPGFESR 11 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 0 FEPES(1)PGFESR;FEPES(1)PGFESR;FEPES(1)PGFESR;FEPES(1)PGFESR ;;; 151.7 0.00050801 256544000 11471.4 9133.7 10667.6 11524.7 11324.5 13457.7 10788.5 9172.4 12386.7 10484.9 TRUE FALSE FALSE 10563.42659 9923.176329 11062.95064 11477.01385 11189.46273 10666.42132 11091.19627 11969.02254 11027.91 10849.24949 0.973655052 0.91464173 1.019697321 1.057862468 1.031358228 0.983148311 1.022300785 1.103212028 1.016467545 1 13.40530763 -6.538524537 24.99923797 0.98104893 1.035400638 0.384518774 0.037549139 207.7150658 331891.4042 0.005781879 0.008178305 2.89E-07 6.538524537 0.054351708 FEPYANPTK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 FEPYANPTKR 10 1 A0A087X0X3;P52272-2;P52272;M0R2T0;M0QYQ7;M0R0N3;M0R019;M0R0Y6 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 1 FEPYANPTK(1)R 77.533 0.016507 2602400 793.74 777.36 647.03 772.06 1227.2 1101.2 1148.8 682.3 1380.9 841.22 FALSE TRUE FALSE 730.9146414 844.5515346 671.009501 768.8654203 1212.566442 872.7987069 1181.032236 890.3301291 1229.418725 870.4523324 0.839695196 0.970244439 0.770874494 0.883294112 1.393030263 1.002695581 1.356802885 1.022836169 1.412390638 1 9.765621485 -5.786508036 24.99525958 0.911018116 1.191828125 0.163675394 0.205018103 126.0326828 125663.3925 0.01827261 0.033131345 1.63E-06 5.786508036 0.280810009 FES(ph)PATGILS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 FESPATGILSPR 12 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 2 0 FES(1)PAT(0.004)GILS(0.996)PR 115.12 0.0097024 4106800 4285.1 3926 4076.4 3815.2 4186 6354.4 5271.9 2935.5 4562.2 3264.8 TRUE FALSE FALSE 3945.929813 4265.345946 4227.47497 3799.413713 4136.084684 5036.425811 5419.815325 3830.520437 4061.738074 3378.251557 1.168039072 1.262589797 1.251379567 1.124668678 1.224327027 1.490838005 1.604325561 1.133876614 1.202319604 1 11.72206105 -6.759540497 0.216684462 0.933847513 1.518215411 0.239109386 0.147236581 1.989891775 0.306667853 0.260809243 0.429992715 1.74E-07 6.759540497 0.584367898 FES(ph)PESQASAEQPEM ddPTM_HeLa_Curcumin_4h_R1 1 FESPESQASAEQPEM 15 0 O75436 O75436 VPS26A Vacuolar protein sorting-associated protein 26A 1 0 FES(0.583)PES(0.377)QAS(0.039)AEQPEM 134.4 0.0006405 5689500 1370.9 1273.7 1309.1 1184.3 1418.7 1795.4 1227.5 751.12 1640.3 1231.1 TRUE FALSE FALSE 1262.391818 1383.792953 1357.616398 1179.39968 1401.782929 1423.013802 1261.940346 980.1330303 1460.363194 1273.880633 0.990981247 1.08628149 1.065732818 0.925832177 1.100403674 1.117069971 0.99062684 0.769407278 1.146389352 1 10.31501438 -4.272816458 4.591070591 1.017176878 0.75593976 0.552508714 0.070829609 0.092269014 5.040874512 0.00829421 0.075870433 5.34E-05 4.272816458 -0.261237118 FES(ph)PEVAER ddPTM_HeLa_Curcumin_4h_R1 2 FESPEVAER 9 0 A0A087X0X3;P52272-2;P52272 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 1 0 FES(1)PEVAER;FES(1)PEVAER ; 133.89 0.0033071 67349000 5295.3 4399.7 4898.5 4921.1 5283.6 5522.1 6008.5 5095.7 4929.6 4302.6 TRUE FALSE FALSE 4876.171417 4779.990463 5080.042719 4900.737792 5220.596521 4376.754213 6177.082339 6649.355472 4388.835213 4452.11503 1.0952483 1.07364487 1.141040311 1.100766211 1.17261043 0.98307303 1.387448954 1.49352733 0.985786572 1 12.12027515 -4.664109114 4.876227538 1.064754127 1.466414934 0.85073842 0.062668747 0.052979582 2.049501518 0.009037843 0.036058303 2.17E-05 4.664109114 0.401660807 FESLEPEMNNQASR ddPTM_HeLa_Curcumin_4h_R1 1 FESLEPEMNNQASR 14 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 155.33 0.0020679 7035000 2309.2 2062.1 2289 1928.8 2297.5 2112.4 2080.1 1460.4 2319.4 1949.2 FALSE FALSE TRUE 2126.424383 2240.338735 2373.832354 1920.819137 2270.103813 1674.264428 2138.462008 1905.669237 2064.967623 2016.934555 1.054285266 1.110764219 1.176950609 0.952345792 1.125521801 0.830103498 1.060253543 0.944834443 1.023814887 1 10.97794856 -5.281329197 24.99143002 1.044498894 0.956582762 0.285355584 0.081472622 933.0391188 1172356.245 0.011316234 0.025335079 5.23E-06 5.281329197 -0.087916132 FESPATGILS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 FESPATGILSPR 12 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 FESPATGILS(1)PR;FESPATGILS(1)PR;FESPATGILS(1)PR;FESPATGILS(1)PR ;;; 157.03 0.00029957 112078000 5820.5 5604.9 5324.3 5293.1 5501.8 5854.7 3564.77 3598.27 5705.1 5384.1 TRUE FALSE FALSE 5359.801283 6089.362581 5521.623242 5271.198555 5436.194628 4640.369224 3664.787852 4695.365959 5079.264803 5571.197074 0.962055589 1.09300793 0.991101763 0.946151874 0.975767785 0.832921392 0.657809768 0.842793011 0.911700795 1 12.44377164 -5.149392516 3.049879997 0.988477994 0.748419653 0.709603579 0.061273866 0.085492073 1.510866904 0.00757807 0.022056969 7.09E-06 5.149392516 -0.240058341 FFDANYDGK ddPTM_HeLa_Curcumin_4h_R1 1 FFDANYDGK 9 0 C9JB30;Q9UPY8;Q9UPY8-2;Q15691 C9JB30;Q9UPY8-2;Q15691 MAPRE3;MAPRE1 Microtubule-associated protein RP/EB family member 3;Microtubule-associated protein RP/EB family member 1 0 0 93.111 0.011007 0 512.54 455.04 568.21 261.4 735.26 767.69 392.6 429.07 531.85 469.23 FALSE FALSE TRUE 471.9719182 494.37163 589.2683624 260.3183961 726.4925047 608.4624404 403.6152994 559.8914678 473.5073856 485.5357076 0.97206428 1.018198296 1.21364578 0.536146759 1.496269983 1.253177533 0.831278304 1.153141693 0.9752267 1 8.923433589 -5.737164661 24.99995855 0.979853398 1.163289532 0.201559601 0.219723372 347.0030399 357368.3201 0.02995771 0.059892203 1.83E-06 5.737164661 0.183436134 FFEHFIEGGR ddPTM_HeLa_Curcumin_4h_R1 2 FFEHFIEGGR 10 0 J3KR44;F5GYJ8;Q96FW1;F5GYN4;F5H6Q1;F5H3F0;Q96FW1-2 J3KR44 OTUB1 Ubiquitin thioesterase OTUB1 0 0 ; ; 102.95 0.008493 67125000 13675.3 10482.5 11981 12418.1 12302.7 14530.9 11263.5 10617.9 12809 12617.5 FALSE FALSE TRUE 12592.88557 11388.56059 12425.0264 12366.71719 12155.99834 11517.02754 11579.5235 13855.24883 11403.88475 13055.95719 0.964531776 0.872288445 0.951674873 0.947208773 0.931069102 0.882128164 0.886914941 1.061220455 0.873462174 1 13.67242061 -7.713126094 2.198963465 0.987800786 0.930476241 0 0.062586381 0.31774555 3.214854222 0.009655661 0.009676795 1.94E-08 7.713126094 -0.057324545 FFEVILIDPFHK ddPTM_HeLa_Curcumin_4h_R1 1 FFEVILIDPFHK 12 0 P61313;A0A2R8YEM3;E7EQV9;E7ENU7 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 0 0 113.77 0.0035597 4239600 3095.6 2315.5 2474.7 2195.1 2669.8 5806.5 4458.7 4074.8 2517.2 3189.9 FALSE FALSE TRUE 2850.579994 2515.641502 2566.414559 2186.017258 2637.964379 4602.166447 4583.799122 5317.187762 2241.069458 3300.748788 0.86361616 0.762142673 0.777524957 0.662279197 0.799201802 1.394279524 1.38871493 1.610903496 0.678957898 1 11.68857763 -5.19920852 4.93794248 0.879788156 1.470442045 0.846895023 0.127482779 0.071471176 3.561141116 0.01938423 0.050606965 6.32E-06 5.19920852 0.590653889 FFFT(ph)Y(ph)LLPHS(ph)APPSLR ddPTM_HeLa_Curcumin_4h_R1 1 FFFTYLLPHSAPPSLR 16 0 Q504Y2 Q504Y2 PKDCC Extracellular tyrosine-protein kinase PKDCC 3 0 FFFT(1)Y(1)LLPHS(0.794)APPS(0.206)LR 65.472 0.018268 2946200 1287.7 971.39 1118 1301.6 953.28 1117.6 950.5 706.25 1209.6 1285.4 TRUE FALSE FALSE 1185.777186 1055.352623 1159.434063 1296.214324 941.9127586 885.7971621 977.1684719 921.5823738 1076.909906 1330.067554 0.891516512 0.793457911 0.871710658 0.974547736 0.708169112 0.665979077 0.734675821 0.692883885 0.809665571 1 10.37728381 -2.283658166 0.131018814 1.074627768 6.61E-17 0.364076572 0.0888798 23.80990629 0.290847553 0.263560999 4.552177211 0.005204054 2.283658166 -1.074627768 FFGVIPSGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 FFGVIPSGKK 10 1 P35251-2;P35251;E0CX09;D6RAD2 P35251-2 RFC1 Replication factor C subunit 1 0 1 ; FFGVIPSGK(1)K;FFGVIPSGK(1)K 91.867 0.0064178 2120180 3254.8 1268.35 2666.45 1729.64 2890.8 4563.7 2412.1 1636.46 2133.31 2513.1 FALSE TRUE FALSE 2997.179146 1377.980522 2765.270983 1722.483208 2856.329098 3617.137177 2479.777034 2135.409121 1899.29123 2600.430038 1.152570576 0.529904863 1.063389879 0.662383984 1.098406439 1.39097654 0.953602673 0.821175378 0.730375823 1 11.34453451 -4.518079287 24.975464 1.028967573 0.854282097 0 0.250374553 388.253368 2020367.163 0.031970375 0.126831218 3.03E-05 4.518079287 -0.174685476 FFMGNQVLK ddPTM_HeLa_Curcumin_4h_R1 1 FFMGNQVLK 9 0 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 0 103.92 0.0010489 0 82.874 0 147.29 64.698 0 0 160.58 0 0 0 FALSE FALSE TRUE 76.31443545 0 152.748697 64.43029682 0 0 165.0854426 0 0 0 0 FFPNDDPEAVS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 FFPNDDPEAVSSPR 14 0 F5H7T0;F6RJM5;Q96S38-2;Q96S38;A0A087X1U5 F5H7T0 RPS6KC1 Ribosomal protein S6 kinase delta-1 1 0 FFPNDDPEAVS(0.67)S(0.33)PR;FFPNDDPEAVS(0.77)S(0.23)PR ; 139.64 0.00077728 14171800 4580.7 3976 4017.8 3595.4 4082.9 6018.1 4925.4 4495.9 4689.6 3824.3 TRUE FALSE FALSE 4218.132761 4319.667723 4166.703202 3580.523187 4034.214084 4769.878222 5063.593468 5866.679213 4175.162613 3957.19414 1.065940313 1.091598635 1.052943842 0.904813628 1.019463271 1.205368767 1.279591875 1.482535101 1.055081572 1 11.95026213 -4.661975182 1.396277686 1.028004072 1.50592302 0.873626241 0.055899162 0.169844056 0.472852057 0.008797937 0.092376227 2.18E-05 4.661975182 0.477918948 FGDPVVQSDMK ddPTM_HeLa_Curcumin_4h_R1 2 FGDPVVQSDMK 11 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 0 ; ; 116.23 0.0025953 4813900 4715.4 3882.9 4374.2 5153.3 4789.4 6016.7 4516.4 4339.8 5117.3 4087.5 FALSE FALSE TRUE 4342.171114 4218.520574 4536.3117 5131.97701 4732.289533 4768.768598 4643.118029 5662.985042 4555.944993 4229.540321 1.026629559 0.997394576 1.072530667 1.213365194 1.118866159 1.127490989 1.097783134 1.338912651 1.077172612 1 12.04628516 -6.479130296 3.960820771 1.012190038 1.168063662 0.536842348 0.067283031 0.116526887 3.846590967 0.009420788 0.014305837 3.32E-07 6.479130296 0.155873624 FGECSNKECPFLHIDPES(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 FGECSNKECPFLHIDPESK 19 1 O95639;C9K0K2;B7Z7B0;H7C016;O95639-3;O95639-2 O95639 CPSF4 Cleavage and polyadenylation specificity factor subunit 4 1 0 FGECSNKECPFLHIDPES(1)K 50.387 0.018726 12617000 864.83 663.64 546.32 610.92 537.87 1016.4 660.42 745.54 748.19 741.6 TRUE FALSE FALSE 796.3777929 721.0020845 566.5670998 608.3921749 531.4562515 805.5871828 678.9496078 972.851714 666.1154289 767.3705448 1.037800836 0.939574876 0.738322709 0.792827115 0.692567958 1.049802065 0.884774132 1.267773073 0.868049254 1 9.583779579 -7.070144875 5.540730379 1.01706162 0.891145997 0.000585154 0.162060073 0.351135074 20.17592067 0.02544974 0.031477238 8.51E-08 7.070144875 -0.125915623 FGESEEVEMEVES(ph)DEEDDKQEK ddPTM_HeLa_Curcumin_4h_R1 18 FGESEEVEMEVESDEEDDKQEK 22 1 Q15459;Q15459-2;H7C1L2 Q15459 SF3A1 Splicing factor 3A subunit 1 1 0 FGESEEVEMEVES(1)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK;FGES(0.009)EEVEMEVES(0.991)DEEDDKQEK;FGES(0.003)EEVEMEVES(0.997)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK;FGES(0.06)EEVEMEVES(0.94)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK;FGES(0.001)EEVEMEVES(0.999)DEEDDKQEK;FGESEEVEMEVES(1)DEEDDKQEK ;;;;;;;;;;;;;;;;; 112.61 7.62E-06 3548391100 49130.68 44853.71 49931.32 45396.94 58217.64 54698.92 48937.17 50932.13 45513.21 43321.42 TRUE FALSE FALSE 45241.93484 48730.66483 51781.81864 45209.09949 57523.43267 43353.74741 50310.21528 66461.10197 40520.52473 44826.83612 1.009260049 1.087086867 1.155152206 1.008527556 1.283236508 0.96713824 1.122323582 1.482618621 0.903934523 1 15.45207506 -1.580429008 1.092975122 1.034591623 199.9997041 0.602813988 0.102852032 323.3283697 1.124758074 0.014218327 160350.8354 0.02627671 1.580429008 198.9651125 FGESTTGFNFS(ph)FK ddPTM_HeLa_Curcumin_4h_R1 1 FGESTTGFNFSFK 13 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 FGESTTGFNFS(1)FK 103.83 0.005369 26128000 691.04 677.07 885.61 767.84 753.93 1288.2 1204.7 261.94 909.46 985.12 TRUE FALSE FALSE 636.3434548 735.5929138 918.4314857 764.6628815 744.9398772 1021.012799 1238.50064 341.8043002 809.6945134 1019.352847 0.624262204 0.72162737 0.900994674 0.750145432 0.730796877 1.001628437 1.214987179 0.335315 0.794322119 1 9.993437808 -4.225973294 23.75272804 0.838374197 0.335312837 0.465735724 0.167124232 8063.987147 5400514.029 0.026719665 7.018794939 5.94E-05 4.225973294 -0.50306136 FGEVVDCTLK ddPTM_HeLa_Curcumin_4h_R1 4 FGEVVDCTLK 10 0 Q14103-3;D6RAF8;Q14103;D6RD83;H0YA96;H0Y8G5;D6RF44;Q14103-4;Q14103-2;D6RBQ9 Q14103-3;Q14103-4 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 0 ;;; ;;; 178.22 1.23E-15 24683800 18338.3 15453.6 16637.6 15586.3 17901 21842.9 17484 17524.9 17680.5 15484.5 FALSE FALSE TRUE 16886.8042 16789.34032 17254.20409 15521.80802 17687.54227 17312.43632 17974.55398 22868.16134 15740.99338 16022.58522 1.053937549 1.047854643 1.076867675 0.968745543 1.103913134 1.080502059 1.121826081 1.427245418 0.982425318 1 13.96781932 -1.075490435 0.923380572 1.030650181 200 0.898536444 0.039338654 172.0022424 0.378737819 0.005726459 72141.49831 0.084044552 1.075490435 198.9693498 LGT(ph)SAEGAHLR ddPTM_HeLa_Curcumin_4h_R1 1 LGTSAEGAHLR 11 0 Q15042-4;Q15042;Q15042-3 Q15042-4 RAB3GAP1 Rab3 GTPase-activating protein catalytic subunit 1 0 LGT(0.812)S(0.188)AEGAHLR 140.91 0.0012484 9361900 3902.6 2988.2 3484.7 3119 3173.4 3080.4 1609.4 731.69 4067.1 3279.8 TRUE FALSE FALSE 3593.705092 3246.486693 3613.846047 3106.094404 3135.559278 2441.490317 1654.555433 954.7789127 3620.949305 3393.772806 1.058911512 0.956601069 1.064846192 0.915233453 0.923915494 0.719402994 0.48752687 0.281332596 1.066939219 1 11.72867427 -4.643525719 0.882752486 1.025293557 0.08065489 0.976860384 0.038848257 0.124817144 0.102742666 0.005837837 0.09957272 2.27E-05 4.643525719 -0.944638666 down FGFAIGSQTTK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 FGFAIGSQTTKK 12 1 Q8WW12;Q8WW12-2 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 0 1 ; FGFAIGSQTTK(1)K;FGFAIGSQTTK(1)K 171.62 4.94E-34 1304200 1749.15 1779.29 1622.41 1496.85 1785.57 2533.9 1404.51 1771.67 1978.76 1651.2 FALSE TRUE FALSE 1610.702932 1933.083899 1682.537942 1490.656431 1764.278244 2008.340577 1443.916771 2311.844027 1761.694979 1708.579077 0.942714887 1.131398555 0.984758601 0.872453872 1.032599701 1.175444909 0.845098006 1.353079912 1.031087763 1 10.73858131 -4.246704887 24.42229082 0.988179744 1.353080268 0.53409352 0.097712566 1047.023405 1735393.048 0.012536284 0.366441176 5.67E-05 4.246704887 0.364900524 FGFGFGGTGK ddPTM_HeLa_Curcumin_4h_R1 1 FGFGFGGTGK 10 0 F1T0B3;A0A087X2G1;Q92499-3;Q92499-2;Q92499 F1T0B3 DDX1 ATP-dependent RNA helicase DDX1 0 0 103.83 0.0072186 728200 156.19 76.444 212.78 244.24 144.87 66.85 190.05 0 157.01 0 FALSE FALSE TRUE 143.8273967 83.05147873 220.665814 243.2293996 143.1425199 52.98455645 195.3822915 0 139.7863958 0 0 FGGKYCT(ph)GER ddPTM_HeLa_Curcumin_4h_R1 2 FGGKYCTGER 10 1 P58397-3;P58397 P58397-3 ADAMTS12 A disintegrin and metalloproteinase with thrombospondin motifs 12 1 0 FGGKYCT(1)GER;FGGKYCT(1)GER ; 99.5 0.010569 115363000 4804.9 3846.3 3518.8 4498.7 3423.2 4706.6 3794 4110.2 4488.4 4302.2 TRUE FALSE FALSE 4424.587095 4178.757033 3649.209823 4480.085571 3382.380576 3730.398106 3900.449429 5363.381059 3996.033749 4451.70113 0.993909287 0.938687686 0.819733786 1.006376089 0.759795071 0.837971373 0.87617055 1.204793606 0.897641965 1 12.12014102 -7.157576918 3.944945154 0.997207018 0.907072415 0.00072288 0.119883259 0.384067865 10.6910915 0.018593743 0.022886674 6.96E-08 7.157576918 -0.090134603 FGGS(ph)GSQVDSAR ddPTM_HeLa_Curcumin_4h_R1 2 FGGSGSQVDSAR 12 0 Q13200;Q13200-2;Q13200-3 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 1 0 FGGS(0.998)GS(0.002)QVDSAR;FGGS(0.674)GS(0.307)QVDS(0.019)AR ; 136.33 0.0016559 73816000 2635.37 2444.7 2849.7 2654.86 2715.63 2998.8 2372.26 2463.5 3121.2 2789.72 TRUE FALSE FALSE 2426.777684 2656.008975 2955.312389 2643.874893 2683.247886 2376.815077 2438.819231 3214.609809 2778.812169 2886.662562 0.840686305 0.920096796 1.023781729 0.915893297 0.929532922 0.823378218 0.844857748 1.113607753 0.962638379 1 11.49518676 -5.461061365 24.9977254 0.930019993 0.911941765 0 0.087203155 1637.977659 662362.042 0.013456016 0.03008855 3.46E-06 5.461061365 -0.018078228 FGHEFLEFEFRPDGK ddPTM_HeLa_Curcumin_4h_R1 1 FGHEFLEFEFRPDGK 15 1 F5H6N1;P61326;Q96A72;P61326-2 F5H6N1 MAGOHB;MAGOH Protein mago nashi homolog;Protein mago nashi homolog 2 0 0 89.189 0.0038523 25090000 9157.3 8175.7 8766.4 8823.9 9061 11557 9384.2 8772.7 8985.2 9108.3 FALSE FALSE TRUE 8432.490042 8882.371078 9091.290496 8787.38904 8952.953493 9159.947926 9647.495396 11447.45585 7999.54604 9424.812747 0.89471168 0.942445364 0.964612321 0.932367494 0.949934363 0.971897073 1.023627276 1.214608306 0.848775064 1 13.20224824 -4.084065278 1.474855763 0.948366889 1.416539211 0.81281208 0.040215463 0.552823244 0.783284267 0.005601855 0.42639969 8.24E-05 4.084065278 0.468172323 FGHVDQENSPSFMFQGS(ph)SNTEFK ddPTM_HeLa_Curcumin_4h_R1 1 FGHVDQENSPSFMFQGSSNTEFK 23 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 FGHVDQENS(0.055)PS(0.055)FMFQGS(0.738)S(0.076)NT(0.076)EFK 50.232 0.016077 3785700 829.14 742.51 578.25 607.21 707.49 1708.6 859.51 567.09 929.1 716.45 TRUE FALSE FALSE 763.5126941 806.6892558 599.6804537 604.6975259 699.0536438 1354.2171 883.6255373 739.9931304 827.1800545 741.3465842 1.029899794 1.088140518 0.808907017 0.815674529 0.94295119 1.826699049 1.191919618 0.998174331 1.115780489 1 9.534004359 AAIAQLNGK(ac)EVK ddPTM_HeLa_Curcumin_4h_R1 1 AAIAQLNGKEVK 12 1 Q96PK6;Q96PK6-2 Q96PK6 RBM14 RNA-binding protein 14 0 1 AAIAQLNGK(1)EVK 158.56 1.56E-05 2691800 2081.7 1981.4 1564.6 1661.9 1463.9 2219.4 1990.6 2394.9 1809.7 1371.9 FALSE TRUE FALSE 1916.931248 2152.663387 1622.585452 1655.023498 1446.443949 1759.071422 2046.450879 3125.093985 1611.180438 1419.573423 1.350357239 1.516415673 1.143009179 1.165859737 1.018928592 1.239154942 1.441595655 2.201431736 1.134975065 1 10.47124175 -4.233544422 2.031068125 1.1849217 2.542108839 0.816513192 0.143360515 0.297377709 1.234330108 0.025170262 0.762208275 5.84E-05 4.233544422 1.357187139 up FGQAATMEGIGAIGGT(ph)PPAFNR ddPTM_HeLa_Curcumin_4h_R1 10 FGQAATMEGIGAIGGTPPAFNR 22 0 Q15233;Q15233-2 Q15233 NONO Non-POU domain-containing octamer-binding protein 1 0 FGQAAT(0.12)MEGIGAIGGT(0.88)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAAT(0.011)MEGIGAIGGT(0.989)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR;FGQAATMEGIGAIGGT(1)PPAFNR ;;;;;;;;; 184.78 5.96E-09 1280950800 14024.06 11145.16 11604.51 11460.69 12053.87 21520.4 19616.21 11017.09 14766.45 10731.53 TRUE FALSE FALSE 12914.04085 12108.49797 12034.58335 11413.2687 11910.13547 17056.82646 20166.58806 14376.15002 13146.60738 11104.44987 1.162960886 1.090418536 1.08376223 1.027810368 1.072555202 1.536035252 1.816081688 1.294629648 1.183904429 1 13.4388503 -5.243739692 5.589168216 1.075679349 1.580529548 0.727129054 0.128728241 0.058401479 6.394656585 0.016892122 0.042246986 5.71E-06 5.243739692 0.504850199 FGQGGAGPVGGQGPR ddPTM_HeLa_Curcumin_4h_R1 2 FGQGGAGPVGGQGPR 15 0 P23246 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 0 ; ; 234.67 7.21E-37 8643300 1424.11 1352.23 1128.05 1382.84 1459.18 1568.2 1473.92 1090.72 1539.33 1187.88 FALSE FALSE TRUE 1311.390191 1469.110736 1169.856525 1377.118174 1441.780232 1242.937643 1515.274228 1423.275507 1370.46935 1229.158742 1.066900593 1.19521644 0.951753818 1.120374552 1.172981311 1.011210026 1.232773422 1.157926522 1.114965304 1 10.26345553 -1.000000029 0.084728381 0.908075842 1.627525622 0.083796426 0.083945668 137.0576559 0.848484215 1.042502352 11.55306882 0.099999993 1.000000029 0.71944978 FGRS(ph)STTQSSETSK ddPTM_HeLa_Curcumin_4h_R1 1 FGRSSTTQSSETSK 14 1 A0A087X0H7;Q8NEL9-2;Q8NEL9-4;Q8NEL9;A0A669KAW5;A0A669KB51;A0A6E1W401;Q8NEL9-3 A0A087X0H7 DDHD1 Phospholipase DDHD1 1 0 FGRS(0.612)S(0.177)T(0.177)T(0.034)QSSETSK 66.059 0.017027 7233000 1260.7 1296.7 1062.1 1054.7 1109.4 1482.3 962.19 1189.1 1343.3 1072.5 TRUE FALSE FALSE 1160.914265 1408.78097 1101.46236 1050.335931 1096.17113 1174.854271 989.1864618 1551.651116 1195.943351 1109.769295 1.046086128 1.269435887 0.992514719 0.946445298 0.987746854 1.058647303 0.891344234 1.398174488 1.077650423 1 10.11604408 -4.248068829 24.44926301 1.025379055 1.398174822 0.571948956 0.095481845 880.6579679 1610325.382 0.012615229 0.317692751 5.65E-05 4.248068829 0.372795767 FGS(ph)NINLEADES ddPTM_HeLa_Curcumin_4h_R1 3 FGSNINLEADES 12 0 Q9NQP4 Q9NQP4 PFDN4 Prefoldin subunit 4 1 0 FGS(1)NINLEADES;FGS(1)NINLEADES;FGS(1)NINLEADES ;; 112.08 0.00496 11803200 9364.8 7433.8 8038.5 8481.6 8515.2 11015.3 9360.2 11181.4 9906.7 8134.3 TRUE FALSE FALSE 8623.566198 8076.344548 8336.413881 8446.505387 8413.661801 8730.602612 9622.82202 14590.55739 8819.959795 8416.96632 1.024545646 0.959531527 0.990429754 1.003509467 0.999607398 1.037262391 1.143264884 1.733469855 1.047878708 1 13.03908463 -4.192071056 2.13826173 1.005843774 2.019529672 0.988243175 0.023662901 0.055847963 0.241922137 0.003108993 0.115123784 6.43E-05 4.192071056 1.013685899 FGST(ph)GSTPPVS(ph)PT(ph)PSER ddPTM_HeLa_Curcumin_4h_R1 1 FGSTGSTPPVSPTPSER 17 0 E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;W0Z7M9;B0QY83;A0A499FIJ6;Q969V6 E7ER32 MKL1;mkl1 MKL/myocardin-like protein 1 3 0 FGS(0.43)T(0.519)GS(0.132)T(0.446)PPVS(0.684)PT(0.769)PS(0.021)ER 72.207 0.01567 5360700 2062.5 1651.7 1551.7 1784.6 1607.4 2094.1 1545.5 1600 1856.6 1771.3 TRUE FALSE FALSE 1899.250949 1794.465588 1609.207367 1777.215798 1588.232805 1659.760055 1588.86257 2087.832635 1652.935625 1832.852543 1.036226813 0.979056168 0.877979722 0.969644724 0.866536051 0.905561149 0.86687965 1.139116533 0.901837756 1 10.83987501 -6.989051594 9.476885088 1.016626423 0.930907905 0 0.08389043 0.202100757 147.0279343 0.011397752 0.014830457 1.03E-07 6.989051594 -0.085718518 FGSTGST(ph)PPVS(ph)PTPSER ddPTM_HeLa_Curcumin_4h_R1 2 FGSTGSTPPVSPTPSER 17 0 E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;W0Z7M9;B0QY83;A0A499FIJ6;Q969V6 E7ER32 MKL1;mkl1 MKL/myocardin-like protein 1 2 0 FGS(0.006)T(0.003)GS(0.072)T(0.92)PPVS(0.997)PT(0.003)PSER;FGS(0.076)T(0.522)GS(0.05)T(0.353)PPVS(0.548)PT(0.43)PS(0.021)ER ; 173.19 0.00017709 154857000 17141.8 14938.1 14712.7 14048.1 13893 14973.5 12667.2 7848.2 17343.9 14171.6 TRUE FALSE FALSE 15785.00844 16229.2828 15257.9656 13989.97268 13727.33505 11867.82731 13022.60754 10241.08005 15441.31756 14664.06205 1.076441739 1.106738552 1.040500617 0.954031198 0.936120906 0.809313768 0.888062769 0.698379482 1.053004107 1 13.83999717 -5.377676178 0.965042255 1.043808528 0.762572976 0.832148923 0.049944907 0.218183981 0.347665205 0.00876616 0.042348803 4.19E-06 5.377676178 -0.281235552 FGSTGST(ph)PPVSPTPSER ddPTM_HeLa_Curcumin_4h_R1 2 FGSTGSTPPVSPTPSER 17 0 E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;W0Z7M9;B0QY83;A0A499FIJ6;Q969V6 E7ER32 MKL1;mkl1 MKL/myocardin-like protein 1 1 0 FGST(0.001)GS(0.006)T(0.97)PPVS(0.022)PTPSER;FGS(0.001)T(0.1)GS(0.133)T(0.69)PPVS(0.075)PT(0.002)PSER ; 150.76 0.00061935 84937000 7270.1 5294.3 6215 6524.5 6452.3 10591 10966.2 2054.89 7806.2 5337.2 TRUE FALSE FALSE 6694.663914 5751.915701 6445.333367 6497.503348 6375.360537 8394.307215 11273.88206 2681.416501 6949.87939 5522.667303 1.212215683 1.041510449 1.16706892 1.176515439 1.154398805 1.519973367 2.041383527 0.485529248 1.25842804 1 12.4311495 -5.365685462 5.438539481 1.110346976 1.416619354 0.048391612 0.364066982 0.331243349 14.21127508 0.046944348 0.106779848 4.31E-06 5.365685462 0.306272378 FGT(ph)FGGLGSK ddPTM_HeLa_Curcumin_4h_R1 1 FGTFGGLGSK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 FGT(1)FGGLGSK 127.52 0.0094815 144090000 3126.5 3148.9 3736.5 4251.1 3291.8 6722.3 6915.6 6111.1 4070.2 5585.3 TRUE FALSE FALSE 2879.034226 3421.076885 3874.977977 4233.510075 3252.547435 5328.019204 7109.633124 7974.346258 3623.709243 5779.388759 0.498155488 0.591944413 0.670482319 0.732518654 0.562783985 0.921900122 1.230170425 1.379790596 0.627005622 1 12.4967012 -4.807478761 2.550862911 0.723692895 1.350926718 0.767078669 0.137641775 0.153474412 1.952404632 0.028618771 0.127426343 1.56E-05 4.807478761 0.627233823 LGAGEGGEAS(ph)VSPEK ddPTM_HeLa_Curcumin_4h_R1 1 LGAGEGGEASVSPEK 15 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 LGAGEGGEAS(0.877)VS(0.123)PEK 112.62 0.001953 575640000 8203.5 6327.3 7219.4 7181.4 8510.6 7816.5 7004 10526 6412.5 5693.7 TRUE FALSE FALSE 7554.184319 6874.203618 7486.957315 7151.68527 8409.116653 6195.26979 7200.51339 13735.32894 5709.064793 5891.555651 1.282205374 1.166789219 1.270794635 1.213887417 1.42731685 1.051550754 1.222175231 2.331358602 0.969025013 1 12.52443291 -4.262384357 5.320590539 1.16943126 2.377930886 0.873061504 0.132024712 0.03988993 4.014240195 0.019355482 0.175338447 5.47E-05 4.262384357 1.208499625 up FGVVVVGVGR ddPTM_HeLa_Curcumin_4h_R1 2 FGVVVVGVGR 10 0 P53004;C9J1E1 P53004 BLVRA Biliverdin reductase A 0 0 ; ; 120.62 1.60E-05 1567800 3742.2 3026.52 3345.82 2844.95 2740.41 4716.9 3891.93 5988.68 3360.89 2659.83 FALSE FALSE TRUE 3446.000921 3288.118903 3469.819032 2833.178351 2707.732401 3738.56177 4001.127081 7814.600964 2992.208776 2752.258895 1.252062779 1.194698257 1.260716802 1.029401106 0.983821837 1.358361227 1.453761159 2.839340797 1.087182889 1 11.42640047 -3.98494178 1.538375804 1.127292399 4.663744009 0.952973444 0.112659427 0.376594307 0.476574936 0.01884716 2.46142476 0.000103528 3.98494178 3.53645161 up FGYVDFESAEDLEK ddPTM_HeLa_Curcumin_4h_R1 2 FGYVDFESAEDLEK 14 0 P19338 P19338 NCL Nucleolin 0 0 ; ; 303.33 7.16E-91 64670000 11406.4 9393.5 10209.9 10373.9 10649.7 13898.1 10789.7 10679.6 12630.9 10691.9 FALSE FALSE TRUE 10503.5714 10205.43228 10588.28788 10330.97555 10522.70928 11015.4774 11092.42994 13935.76088 11245.32187 11063.44273 0.949394475 0.922446343 0.957051809 0.93379392 0.951124306 0.99566452 1.00262009 1.259622454 1.016439651 1 13.43351277 -4.169358398 2.296780523 0.966485303 1.381195596 0.903272372 0.028653152 0.192937938 0.948682295 0.004233259 0.175241724 6.77E-05 4.169358398 0.414710293 FHALS(ph)SPQSPFPSTPTSR ddPTM_HeLa_Curcumin_4h_R1 1 FHALSSPQSPFPSTPTSR 18 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 FHALS(0.499)S(0.499)PQS(0.001)PFPSTPTSR 70.917 0.0063923 14025000 3248.6 2341.6 2705.6 2603.4 3244.7 4337.7 2382.2 4041.9 3802.4 2982.5 TRUE FALSE FALSE 2991.469882 2543.99747 2805.871916 2592.627821 3206.009072 3438.012124 2449.038121 5274.256703 3385.286233 3086.141653 0.969323582 0.824329456 0.909184422 0.840087109 1.038840543 1.114016306 0.793559854 1.709013162 1.096931578 1 11.59158857 -4.253427935 24.91905508 0.962238922 1.709013544 0.818358382 0.106644235 265.0176052 824299.472 0.013143956 0.192947328 5.58E-05 4.253427935 0.746774622 FHDFDHR ddPTM_HeLa_Curcumin_4h_R1 1 FHDFDHR 7 0 Q15424-2;Q15424;Q15424-4;Q15424-3;K7EII0;Q14151 Q15424-2;Q14151 SAFB;SAFB2 Scaffold attachment factor B1;Scaffold attachment factor B2 0 0 127.12 0.0066578 23369000 1856.5 1372.9 1536.8 1875 1584.3 1919.3 1786.9 1594 1797.1 1452 FALSE FALSE TRUE 1709.556066 1491.567358 1593.75516 1867.241747 1565.408257 1521.215545 1837.035605 2080.003262 1599.962626 1502.456892 1.137840344 0.992752182 1.060765982 1.242792227 1.041898949 1.012485319 1.222687729 1.384401292 1.064897525 1 10.55310788 -4.494821217 3.132361296 1.069315423 1.377104093 0.661342819 0.071389274 0.132628711 2.410603671 0.011027124 0.074940073 3.20E-05 4.494821217 0.30778867 FHDTS(ph)SPLMVTPPSAEAHWAVR ddPTM_HeLa_Curcumin_4h_R1 2 FHDTSSPLMVTPPSAEAHWAVR 22 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 0 FHDT(0.267)S(0.363)S(0.363)PLMVT(0.007)PPS(0.001)AEAHWAVR;FHDT(0.173)S(0.614)S(0.213)PLMVTPPSAEAHWAVR ; 92.416 0.00031308 7429100 2347.15 2327.35 2252.74 2570.51 3120.05 3600.82 2626.28 2111.83 3299.64 2878.09 TRUE FALSE FALSE 2161.370601 2528.515764 2336.228526 2559.873911 3082.845442 2853.969342 2699.966349 2755.717245 2937.677747 2978.103413 0.725754046 0.849035582 0.78446857 0.859565151 1.035170716 0.958317743 0.906605975 0.925326244 0.986425701 1 11.54017814 -5.857607451 12.71638847 0.857778449 0.952918655 0.208886898 0.083282677 0.831137994 104.8251232 0.016118925 0.029224983 1.39E-06 5.857607451 0.095140206 FHDTSS(ph)PLMVTPPSAEAHWAVR ddPTM_HeLa_Curcumin_4h_R1 1 FHDTSSPLMVTPPSAEAHWAVR 22 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 0 FHDT(0.067)S(0.214)S(0.704)PLMVT(0.015)PPSAEAHWAVR 72.383 0.0013347 11607000 2528.6 2738.2 2158.4 2235.3 3879.7 5280.8 3205.2 2843.9 4020.9 2998.1 TRUE FALSE FALSE 2328.458642 2974.877807 2238.392203 2226.050921 3833.437111 4185.502553 3295.129286 3710.992018 3579.81733 3102.283752 0.750562756 0.958931563 0.721530454 0.717552326 1.235682297 1.34916819 1.062162442 1.196212956 1.153929691 1 11.59911493 -5.74905373 24.99953276 0.862179889 1.210072116 0.548871267 0.144465926 115.069751 232258.4235 0.019213894 0.038211084 1.78E-06 5.74905373 0.347892227 FHINWEDNTEKLEDAESS(ph)NPNLQSLLSTDALPSASK ddPTM_HeLa_Curcumin_4h_R1 1 FHINWEDNTEKLEDAESSNPNLQSLLSTDALPSASK 36 1 Q9Y294 Q9Y294 ASF1A Histone chaperone ASF1A 1 0 FHINWEDNT(0.003)EKLEDAES(0.215)S(0.636)NPNLQS(0.096)LLS(0.025)T(0.025)DALPSASK 48.088 0.0042439 25020000 582.37 741.63 580.72 769.11 740.21 1109 1303 1222.6 1240.4 841.8 TRUE FALSE FALSE 536.2748 805.7331926 602.2419941 765.9276266 731.3834792 878.980899 1339.558673 1595.365112 1104.331223 871.0524873 0.615663014 0.925011069 0.691395757 0.879312829 0.839654889 1.009102106 1.537862175 1.83153729 1.26781249 1 9.766615844 -4.685938242 1.803803566 0.816979729 1.872789699 0.762531263 0.176087674 0.116640262 0.639254937 0.021062047 0.157853835 2.06E-05 4.685938242 1.055809969 FHLGLFTDR ddPTM_HeLa_Curcumin_4h_R1 1 FHLGLFTDR 9 0 Q8TEQ6 Q8TEQ6 GEMIN5 Gem-associated protein 5 0 0 74.162 0.018518 2130200 1382.4 945.51 1363.1 1099 1507 1595.8 1458.6 1100.3 1184.4 1252.9 FALSE FALSE TRUE 1272.981581 1027.235671 1413.617685 1094.452629 1489.030009 1264.813092 1499.52439 1435.776405 1054.474283 1296.438182 0.981906889 0.79235222 1.090385724 0.844199627 1.148554578 0.975606172 1.156649358 1.107477722 0.813362564 1 10.3403377 -5.106297506 1.168758862 0.976295228 1.13282893 0.267669872 0.111142061 0.600251551 1.363702439 0.01379814 0.078457916 7.83E-06 5.106297506 0.156533702 FHPEPYGLEDDQR ddPTM_HeLa_Curcumin_4h_R1 1 FHPEPYGLEDDQR 13 0 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12 O60716 CTNND1 Catenin delta-1 0 0 110.15 0.0032062 6993200 4600.2 4822.9 5043.2 5247.6 4605.3 4425.3 3014.2 2588.4 5108.9 4920 FALSE FALSE TRUE 4236.089316 5239.769986 5230.105428 5225.886822 4550.384805 3507.442897 3098.77034 3377.591244 4548.466452 5090.969634 0.832079077 1.029228293 1.02732992 1.026501275 0.893814957 0.688953804 0.608679792 0.663447533 0.893438142 1 12.31372475 -5.256491447 3.20250313 0.943932641 0.638689784 0.826104914 0.064285428 0.099741365 2.110839922 0.012033848 0.031997328 5.54E-06 5.256491447 -0.305242857 FHPEPYGLEDDQRS(ph)MGYDDLDYGMMSDYGTAR ddPTM_HeLa_Curcumin_4h_R1 1 FHPEPYGLEDDQRSMGYDDLDYGMMSDYGTAR 32 1 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12 O60716 CTNND1 Catenin delta-1 1 0 FHPEPY(0.029)GLEDDQRS(0.497)MGY(0.446)DDLDY(0.023)GMMS(0.003)DY(0.001)GT(0.001)AR 41.418 0.010594 4683100 810.94 823.26 607.29 967.24 859.74 1236.5 1089.3 865.97 1378.3 945.22 TRUE FALSE FALSE 746.7532433 894.418926 629.7967016 963.2378172 849.488162 980.0359618 1119.862826 1130.000267 1227.103938 978.0663246 0.763499596 0.914476762 0.643920239 0.984838955 0.868538401 1.002013807 1.144976366 1.155341144 1.254622419 1 9.93378849 -4.953273262 1.935181122 0.874161265 1.166005754 0.225783672 0.155013269 0.23330497 1.656965992 0.016711681 0.074435919 1.11E-05 4.953273262 0.291844489 FHQLDIDDLQSIR ddPTM_HeLa_Curcumin_4h_R1 2 FHQLDIDDLQSIR 13 0 P16152;E9PQ63;A8MTM1;P16152-2;O75828 P16152 CBR1;CBR3 Carbonyl reductase [NADPH] 1;Carbonyl reductase [NADPH] 3 0 0 ; ; 223.36 2.68E-14 175022000 8699 6900.9 7294.1 7333.2 7590.2 11857.9 8014.7 8414.3 8051.5 7267.7 FALSE FALSE TRUE 8010.464971 7497.383046 7564.425763 7302.857161 7499.691822 9398.437874 8239.570912 10979.78134 7168.270594 7520.252034 1.065185706 0.996959013 1.005873969 0.971092076 0.997266021 1.249750385 1.0956509 1.460028372 0.953195526 1 12.8765653 -1.000000188 0.740522158 1.022276422 71.45090172 0.785915276 0.069753832 108.3981785 0.456262392 0.01045429 12733.07518 0.099999957 1.000000188 70.42862529 FHS(ph)PSTTWSPNKDTPQEK ddPTM_HeLa_Curcumin_4h_R1 1 FHSPSTTWSPNKDTPQEK 18 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 0 FHS(0.434)PS(0.434)T(0.093)T(0.036)WS(0.003)PNKDT(0.001)PQEK 50.077 0.018777 44802000 4297.8 3650.3 3436.8 3773.7 4664.3 6026.2 3625.1 4855.1 4645.2 4175.4 TRUE FALSE FALSE 3957.624595 3965.815667 3564.170831 3758.085429 4608.681269 4776.298191 3726.81055 6335.39764 4135.633182 4320.494839 0.916011879 0.917907743 0.82494505 0.869827547 1.066702181 1.105497951 0.862588821 1.466359266 0.957212851 1 12.07698084 -4.255177417 24.88052367 0.953591702 1.46635951 0.769727701 0.085187945 249.9872259 993239.7034 0.012196653 0.152049633 5.56E-05 4.255177417 0.512767808 FHSEDYIDFLQR ddPTM_HeLa_Curcumin_4h_R1 1 FHSEDYIDFLQR 12 0 O15379;O15379-2 O15379 HDAC3 Histone deacetylase 3 0 0 89.44 0.012508 4642500 1471.7 1400.7 1343.5 1473.4 1413.1 2240.8 1356.5 990.91 1619.3 1439.2 FALSE FALSE TRUE 1355.213392 1521.770267 1393.291292 1467.303461 1396.249705 1776.032821 1394.559739 1293.033897 1441.666841 1489.212093 0.910020405 1.021862684 0.935589563 0.985288441 0.937576126 1.192598979 0.936441321 0.868267122 0.968073553 1 10.54033352 FHSPS(ph)TTWSPNKDTPQEK ddPTM_HeLa_Curcumin_4h_R1 2 FHSPSTTWSPNKDTPQEK 18 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 0 FHS(0.005)PS(0.835)T(0.128)T(0.032)WSPNKDTPQEK;FHS(0.081)PS(0.729)T(0.095)T(0.095)WSPNKDTPQEK ; 92.977 0.0010285 91359000 6409.2 6198.8 5760.9 5855.8 7474.5 9520.6 5495.2 6962.6 8105.9 6639.4 TRUE FALSE FALSE 5901.905057 6734.596651 5974.404022 5831.570251 7385.371469 7545.920241 5649.380522 9085.464688 7216.70305 6870.118656 0.859068868 0.980273702 0.869621665 0.848831082 1.074999114 1.098368255 0.822311929 1.322461102 1.050448094 1 12.7461193 -4.250249683 24.77635905 0.940309179 1.322461354 0.557178678 0.097109788 800.9708514 1773481.782 0.013070971 0.266850951 5.62E-05 4.250249683 0.382152175 FHSPST(ph)T(ph)WSPNKDTPQEK ddPTM_HeLa_Curcumin_4h_R1 1 FHSPSTTWSPNKDTPQEK 18 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 2 0 FHS(0.395)PS(0.33)T(0.622)T(0.622)WS(0.032)PNKDTPQEK 84.195 0.0030299 32852000 3675 2862.5 3083.3 3000.4 3485.4 4021.2 3058.4 1643.7 3255.1 3103.2 TRUE FALSE FALSE 3384.119872 3109.921745 3197.56981 2987.98514 3443.838881 3187.157792 3144.210473 2144.856563 2898.023674 3211.035969 1.053902823 0.968510404 0.995806288 0.930536179 1.072500873 0.992563715 0.979188805 0.667964042 0.902519842 1 11.64882311 -4.242914681 3.216798937 1.014241863 0.610040276 0.760349559 0.052538753 0.096527651 1.504576846 0.005693549 0.099337317 5.72E-05 4.242914681 -0.404201587 FHVEEEGK ddPTM_HeLa_Curcumin_4h_R1 4 FHVEEEGK 8 0 P00558;P00558-2;P07205 P00558 PGK1;PGK2 Phosphoglycerate kinase 1;Phosphoglycerate kinase 2 0 0 ;;; ;;; 139.97 0.00043856 95000400 34105.7 29495.2 32900.3 32475.8 37953.4 37913.7 33319.7 29357 29650 26495.7 FALSE FALSE TRUE 31406.19786 32044.63366 34119.61406 32341.42374 37500.83049 30049.97124 34254.56111 38307.81416 26397.46918 27416.4236 1.145524971 1.16881159 1.244495437 1.179636856 1.367823573 1.096057301 1.249417561 1.397257889 0.96283416 1 14.74275277 -13.17018761 0.053968243 5.38E-12 1.717261408 0.669531363 0.076989788 152.8862207 0.694406253 22.13480024 5.346441257 6.76E-14 13.17018761 1.717261408 FHVEEEGK(ac)GK ddPTM_HeLa_Curcumin_4h_R1 2 FHVEEEGKGK 10 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 1 ; FHVEEEGK(1)GK;FHVEEEGK(1)GK 123.51 0.0030505 33626000 16094.4 15412.8 13493.5 13489 19195.4 23033 19950.7 16783.9 21248.2 12915.3 FALSE TRUE FALSE 14820.51126 16745.01375 13993.58098 13433.18609 18966.50739 18255.69616 20510.46295 21901.23385 18917.32562 13364.10571 1.1089789 1.252984233 1.047101937 1.005169098 1.419212613 1.366024525 1.534742645 1.638810281 1.415532474 1 13.70607568 -4.163021819 0.42741272 1.038277391 2.188686498 0.510007556 0.15286936 1.601736109 0.185700554 0.024538791 0.951436169 6.87E-05 4.163021819 1.150409107 FICVTPTTCSNTIDLPMS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 FICVTPTTCSNTIDLPMSPR 20 0 G8JLH9;P40763-2;P40763 G8JLH9 STAT3 Signal transducer and activator of transcription;Signal transducer and activator of transcription 3 1 0 FICVTPTTCSNTIDLPMS(1)PR 126.16 3.62E-05 16490000 826.82 821.87 717.62 744.77 762.79 1302.3 891.55 925.61 924.89 859.12 TRUE FALSE FALSE 761.3763245 892.9087806 744.2156285 741.6883391 753.6942274 1032.1883 916.5644935 1207.824228 823.431881 888.9743561 0.856466015 1.004425802 0.837162088 0.834319161 0.847824487 1.161100197 1.031035921 1.358671619 0.926271805 1 9.795997992 -3.961608225 0.962850134 0.920284742 1.794875835 0.69871323 0.08794437 1.488642466 0.71682809 0.014461872 1.547265435 0.000109243 3.961608225 0.874591093 FIDTTSK ddPTM_HeLa_Curcumin_4h_R1 1 FIDTTSK 7 0 G5E9G0;P39023;Q92901 G5E9G0 RPL3;RPL3L 60S ribosomal protein L3;60S ribosomal protein L3-like 0 0 147.69 0.0016003 10227000 7068.9 4813.1 6482.7 6614.6 5772.8 6919.7 5720.1 5509 6383.5 5217.5 FALSE FALSE TRUE 6509.389106 5229.122917 6722.954565 6587.230538 5703.96313 5484.476219 5880.590611 7188.66874 5683.246021 5398.807737 1.205708635 0.968569946 1.245266528 1.220126898 1.056522738 1.015868037 1.089238754 1.331528939 1.052685389 1 12.39842512 -9.516273104 1.21123891 0.998372164 1.141452904 0.150851445 0.107253178 0.640760392 1.651395621 0.077735332 0.017830047 3.05E-10 9.516273104 0.14308074 FIHQQPQSSS(ph)PVYGSSAK ddPTM_HeLa_Curcumin_4h_R1 2 FIHQQPQSSSPVYGSSAK 18 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-3;A0A1B0GU60;F5H836 A0A1B0GTU4 PXN Paxillin 1 0 FIHQQPQSS(0.071)S(0.929)PVYGSSAK;FIHQQPQS(0.003)S(0.198)S(0.798)PVYGS(0.001)SAK ; 121.47 0.00015729 681230000 8116.4 6707.6 7050.2 6640.3 7567.6 8085.6 4672.1 5172.3 8807.9 6259.1 TRUE FALSE FALSE 7473.978376 7287.375056 7311.486614 6612.824198 7477.361313 6408.555417 4803.186552 6749.31046 7841.695406 6476.603259 1.153996636 1.125184725 1.128907596 1.021032775 1.154518968 0.989493282 0.741621242 1.042106516 1.210772853 1 12.66102166 -4.998110885 24.99583461 1.082963133 0.885287184 0.464256148 0.09292219 39.89043336 527774.093 0.012031634 0.035741579 1.00E-05 4.998110885 -0.197675949 FIIHAPPGEFNEVFNDVR ddPTM_HeLa_Curcumin_4h_R1 2 FIIHAPPGEFNEVFNDVR 18 0 C9JUG7;F8W9N7;P47755-2;P47755;A0A0D9SET8 C9JUG7 CAPZA2 F-actin-capping protein subunit alpha-2 0 0 ; ; 99.747 0.0012192 34932000 6106.1 5022.9 5522.7 5255.3 4803.7 9522.1 5901.5 5874.2 6366.3 6033.5 FALSE FALSE TRUE 5622.795742 5457.057094 5727.37612 5233.554961 4746.419015 7547.109124 6067.080207 7665.216539 5667.932818 6243.163676 0.900632441 0.87408522 0.917383624 0.838285721 0.760258622 1.208859725 0.971795795 1.227777604 0.907862281 1 12.60806157 -5.247695588 24.99941865 0.923291884 1.119709515 0.589324447 0.091870955 542.1577464 986161.7218 0.013506973 0.034238066 5.65E-06 5.247695588 0.196417632 FIIPNVVK ddPTM_HeLa_Curcumin_4h_R1 1 FIIPNVVK 8 0 P00338;P00338-3;P00338-5;P00338-2;F5GYU2;F5GXY2 P00338 LDHA L-lactate dehydrogenase A chain 0 0 114.19 0.0041771 4742400 7341.8 4790.2 6202.8 4899.4 5720.7 7639.6 5406.1 5478.9 5377 4998 FALSE FALSE TRUE 6760.688783 5204.243543 6432.681225 4879.127581 5652.484389 6055.060844 5557.780616 7149.391388 4787.156553 5171.680128 1.307251921 1.006296487 1.24382813 0.943431817 1.092968677 1.170811167 1.074656684 1.382411752 0.925648229 1 12.33641733 -9.711392175 1.616545628 1.000140553 1.16820254 0.234256178 0.129977733 0.525479968 2.481450858 0.092614707 0.020414404 1.94E-10 9.711392175 0.168061987 FIIPQIVK ddPTM_HeLa_Curcumin_4h_R1 1 FIIPQIVK 8 0 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;C9J7H8 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain;L-lactate dehydrogenase 0 0 93.262 0.019579 764620 1992.6 2300.4 2337.1 2428.3 2392.8 2691.2 2420.1 2443.2 2221.9 1858.3 FALSE FALSE TRUE 1834.883607 2499.236326 2423.714982 2418.252338 2364.267423 2133.014784 2488.001493 3188.120433 1978.163129 1922.875787 0.954239281 1.29973883 1.260463624 1.257622752 1.229547659 1.109283709 1.293896106 1.657996036 1.028752425 1 10.90904986 -1 0.206744481 0.938834459 3.780464359 0.576659163 0.125743138 25.58500362 0.298079712 0.120370147 23.99031181 0.1 1 2.841629901 FINDQYEK ddPTM_HeLa_Curcumin_4h_R1 1 FINDQYEK 8 0 Q9UHD8;Q9UHD8-5;Q9UHD8-2;Q9UHD8-7;Q9UHD8-3;Q9UHD8-8;Q9UHD8-9;Q9UHD8-4;K7EL40;K7EK18;K7EQD7;K7EIE4;K7ELJ9;K7ER52 Q9UHD8 9-Sep Septin-9 0 0 102.07 0.011527 1556300 779.06 669.95 592.21 534.65 820.19 876.37 741.17 729.76 862.86 774.88 FALSE FALSE TRUE 717.3965789 727.8574928 614.1578236 532.43776 810.4097699 694.6009833 761.9652354 952.2604646 768.2064168 801.8070223 0.894724739 0.907771412 0.76596713 0.664047265 1.0107292 0.866294462 0.950310005 1.187642959 0.9580939 1 9.647111243 -4.272055318 3.671502091 0.912290929 1.214835661 0.421341685 0.102494246 0.226505849 5.638743393 0.015575847 0.183571087 5.34E-05 4.272055318 0.302544733 FIPCS(ph)PFSDYVYK ddPTM_HeLa_Curcumin_4h_R1 2 FIPCSPFSDYVYK 13 0 Q14195-2;Q14195 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 1 0 FIPCS(0.999)PFS(0.001)DYVYK;FIPCS(0.89)PFS(0.11)DYVYK ; 120.87 0.0023922 0 2940.8 2196.43 2383.4 2752.6 2579.9 3901.3 2836.9 2603.2 2420 2359.7 TRUE FALSE FALSE 2708.032577 2386.279622 2471.730901 2741.210471 2549.136377 3092.126403 2916.495779 3396.903696 2154.532055 2441.699399 1.109076972 0.977302785 1.012299426 1.122665006 1.044000903 1.266382915 1.194453248 1.391204707 0.882390377 1 11.25366988 -4.250217499 0.658027774 1.042200599 1.588087903 0.714303817 0.076573737 1.135069813 0.333226016 0.010767791 0.465316096 5.62E-05 4.250217499 0.545887304 FIPHENGVHTIDVK ddPTM_HeLa_Curcumin_4h_R1 1 FIPHENGVHTIDVK 14 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3 O75369-8 FLNB Filamin-B 0 0 64.374 0.012246 23529000 3422.3 2642.9 2969.3 3331.5 2773.8 3831.5 2982.8 2241.9 4076.5 3316.1 FALSE FALSE TRUE 3151.421344 2871.340499 3079.34487 3317.715136 2740.724247 3036.80371 3066.48934 2925.44499 3629.318149 3431.334228 0.918424477 0.836800005 0.897419099 0.96688778 0.798734272 0.885021251 0.893672588 0.852567775 1.057698816 1 11.74455394 -8.485361247 0.454025397 1.011867887 0.870547282 0.605205591 0.046725911 0.65357977 0.275482883 0.040622192 0.014768891 3.27E-09 8.485361247 -0.141320606 FIQELSGS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 FIQELSGSSPK 11 0 I3L254;Q01664 I3L254 TFAP4 Transcription factor AP-4 1 0 FIQELSGS(0.724)S(0.276)PK 130.69 0.0027423 432850000 8746.3 6662.9 7177 7703.6 7381.8 8164.4 6660.7 5096.3 9095.6 8113.3 TRUE FALSE FALSE 8054.021126 7238.811387 7442.985934 7671.724544 7293.776856 6471.011408 6847.581316 6650.13841 8097.835436 8395.236571 0.959356066 0.862252222 0.886572507 0.913818745 0.868799443 0.7707956 0.815650787 0.792132342 0.964575014 1 13.03535526 -6.060422301 0.316672119 1.009226888 0.736193308 0.810748466 0.031715343 0.65140557 0.116539808 0.018436238 0.064959847 8.70E-07 6.060422301 -0.27303358 FIQELSGSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 FIQELSGSSPK 11 0 I3L254;Q01664 I3L254 TFAP4 Transcription factor AP-4 1 0 FIQELS(0.001)GS(0.233)S(0.766)PK 97.957 0.012337 427980000 6218.6 5050.8 5488.2 5611.5 5399.9 6234.2 5005.5 3718.8 5914.6 5509.2 TRUE FALSE FALSE 5726.391248 5487.368646 5691.59752 5588.2811 5335.509719 4941.156646 5145.940858 4852.645001 5265.783178 5700.64429 1.0045165 0.962587449 0.998413027 0.980289388 0.935948543 0.866771613 0.902694607 0.851245009 0.923717199 1 12.47690927 -5.56601095 1.663452772 0.998651965 0.872721801 0.696106204 0.029249519 0.071896372 0.394031166 0.002497895 0.006739996 2.72E-06 5.56601095 -0.125930164 FIQELSGSS(ph)PKR ddPTM_HeLa_Curcumin_4h_R1 1 FIQELSGSSPKR 12 1 I3L254;Q01664 I3L254 TFAP4 Transcription factor AP-4 1 0 FIQELS(0.001)GS(0.152)S(0.848)PKR 85.976 0.0088927 58695000 1297.3 1427.7 1085.6 1223 1418.5 1938.5 1506.4 802.33 1423.3 1427.8 TRUE FALSE FALSE 1194.617336 1551.104026 1125.833291 1217.93955 1401.585314 1536.433249 1548.66553 1046.956724 1267.167551 1477.415944 0.808585653 1.049876328 0.762028659 0.824371468 0.948673473 1.039946303 1.048225814 0.708640466 0.857691807 1 10.52886034 -4.235270948 23.36187416 0.919980064 0.70863979 0.286849186 0.102623883 3853.174225 3439791.919 0.015297053 1.39821075 5.82E-05 4.235270948 -0.211340275 FIQENVFVAANHNGS(ph)PLSIK ddPTM_HeLa_Curcumin_4h_R1 2 FIQENVFVAANHNGSPLSIK 20 0 E9PFD2;P11172-4;P11172-2;P11172-3;P11172 E9PFD2 UMPS Uridine 5-monophosphate synthase;Orotate phosphoribosyltransferase;Orotidine 5-phosphate decarboxylase 1 0 FIQENVFVAANHNGS(0.986)PLS(0.014)IK;FIQENVFVAANHNGS(0.996)PLS(0.004)IK ; 140.07 3.29E-05 275520000 5001.8 3948.7 4148.1 4150 4838.3 7399.5 4684.4 3101.2 4666 4077.6 TRUE FALSE FALSE 4605.902252 4290.008033 4301.832235 4132.8284 4780.606432 5864.76029 4815.831657 4046.741604 4154.151474 4219.296296 1.091628065 1.01675913 1.019561541 0.97950656 1.133034065 1.389985409 1.141382666 0.959103443 0.984560264 1 12.04278669 -5.577713557 7.337648317 1.036609672 1.177574403 0.29840899 0.102575225 0.211538768 23.56666321 0.014842403 0.029861966 2.64E-06 5.577713557 0.140964731 FIQESEEK ddPTM_HeLa_Curcumin_4h_R1 1 FIQESEEK 8 0 Q13129 Q13129 RLF Zinc finger protein Rlf 0 0 161.68 0.0066514 38349000 3692.2 2873.3 3243 3203.1 3699.9 3838.3 3314.4 3064.3 4092.3 3762.1 FALSE FALSE TRUE 3399.958474 3121.655249 3363.188433 3189.846421 3655.781109 3042.193313 3407.393144 3998.590964 3643.384928 3892.832695 0.873389313 0.801898128 0.863943739 0.819415236 0.939105632 0.781485759 0.875299149 1.027167432 0.935921272 1 11.92660463 -8.962095725 0.855579121 0.997455072 0.868612721 0.210675393 0.069443015 0.496076029 0.682987216 0.038016794 0.012969502 1.09E-09 8.962095725 -0.128842351 FITHAPPGEFNEVFNDVR ddPTM_HeLa_Curcumin_4h_R1 2 FITHAPPGEFNEVFNDVR 18 0 P52907 P52907 CAPZA1 F-actin-capping protein subunit alpha-1 0 0 ; ; 115.87 0.00036802 54061000 2844.3 2079.51 2331.3 2103.7 2035.24 4654.5 3211.3 2735.7 3104.1 2474.5 FALSE FALSE TRUE 2619.170654 2259.253578 2417.700029 2094.995447 2010.971092 3689.104233 3301.400435 3569.802336 2763.587996 2560.488691 1.022918267 0.882352492 0.944233824 0.818201406 0.785385657 1.440781303 1.289363412 1.394187894 1.079320524 1 11.32220347 -5.251741237 24.99926497 0.968227627 1.366236148 0.81247238 0.096166121 243.883895 628667.0483 0.014333977 0.03603582 5.60E-06 5.251741237 0.398008521 FITIFGTR ddPTM_HeLa_Curcumin_4h_R1 2 FITIFGTR 8 0 P08758;D6RBE9;D6RBL5 P08758 ANXA5 Annexin A5;Annexin 0 0 ; ; 108.09 0.0075642 15657600 2673.4 1441.27 2172.9 1820.16 2578.4 2979.3 2415.5 1938.45 1819.35 1962.99 FALSE FALSE TRUE 2461.797569 1565.846957 2253.429585 1812.62866 2547.654264 2361.359596 2483.272429 2529.474481 1619.771857 2031.203756 1.211989472 0.770896052 1.109405976 0.892391349 1.254258346 1.16254196 1.222561952 1.245308096 0.7974443 1 10.98811925 -5.716045668 24.99996061 1.062795374 1.217079804 0.314490702 0.14772011 148.6869409 81886.47494 0.01943454 0.038868947 1.92E-06 5.716045668 0.154284429 FK(ac)MPEMNIK ddPTM_HeLa_Curcumin_4h_R1 1 FKMPEMNIK 9 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 1 FK(1)MPEMNIK 99.653 0.0022056 0 666.56 490.36 602.1 724.83 842.14 387.3 395.57 449.69 680.55 520.16 FALSE TRUE FALSE 613.8010726 532.7445334 624.4143557 721.8308455 832.0980305 306.9696142 406.6686296 586.7984109 605.8953677 538.2355213 1.140394954 0.989798169 1.160113614 1.341105923 1.54597383 0.570325819 0.755558884 1.090226096 1.125706765 1 9.072093796 -5.236032215 24.99686386 1.117867378 0.800389176 0.401751963 0.201172379 710.7198793 699241.4952 0.02956807 0.075355051 5.81E-06 5.236032215 -0.317478202 FKDDDGDEEDENGVGDAELR ddPTM_HeLa_Curcumin_4h_R1 2 FKDDDGDEEDENGVGDAELR 20 1 Q6NZY4 Q6NZY4 ZCCHC8 Zinc finger CCHC domain-containing protein 8 0 0 ; ; 182.47 4.16E-16 14147000 4662.7 4085.2 4310.6 4627.3 4717.2 4828.9 4130.6 4755.4 4809.9 4339.7 FALSE FALSE TRUE 4293.642375 4438.306485 4470.354628 4608.153459 4660.950471 3827.331707 4246.493519 6205.299569 4282.266004 4490.504252 0.956160407 0.988375968 0.995512837 1.026199554 1.037957033 0.852316687 0.945660728 1.381871438 0.953626979 1 12.13266174 -4.258694889 24.9615099 0.977488628 1.381871586 0.858983538 0.049683658 66.65082663 606163.4234 0.006864981 0.063446038 5.51E-05 4.258694889 0.404382958 FKGPGDTSNFDDYEEEEIR ddPTM_HeLa_Curcumin_4h_R1 1 FKGPGDTSNFDDYEEEEIR 19 1 K7ERP6;P17612-2;P17612 K7ERP6 PRKACA cAMP-dependent protein kinase catalytic subunit alpha 0 0 106.16 0.00054935 8289100 1347.4 1137.3 1469.2 1446.5 1203.7 1427.7 1152.1 746.2 1226.2 1445.5 FALSE FALSE TRUE 1240.751868 1235.603144 1523.649844 1440.514766 1189.346664 1131.578927 1184.424825 973.7129449 1091.688928 1495.731017 0.829528741 0.826086462 1.018665674 0.963084104 0.795160794 0.756539052 0.791870204 0.650994687 0.72986982 1 10.54663504 -2.58600732 0.306252869 0.939662462 4.57E-35 0.294465374 0.096494257 12.85539371 0.389448213 0.033108941 5.565889186 0.002594136 2.58600732 -0.939662462 FKIPGS(ph)PPESMGR ddPTM_HeLa_Curcumin_4h_R1 1 FKIPGSPPESMGR 13 1 V9GYJ7;V9GYF8;Q5SX90;Q5SX86;Q5SX87;P50395;P50395-2 V9GYJ7 GDI2 Rab GDP dissociation inhibitor beta 1 0 FKIPGS(0.984)PPES(0.016)MGR 74.783 0.012607 59834000 5223.4 4128.2 4507.6 4487.6 4443.7 5785.2 4418.8 4308.5 5587.3 5035.4 TRUE FALSE FALSE 4809.962378 4485.023213 4674.655621 4469.0315 4390.71178 4585.284307 4542.779635 5622.141816 4974.387169 5210.379775 0.923150055 0.86078624 0.897181362 0.857717037 0.842685556 0.880028809 0.871871117 1.079027261 0.954707216 1 12.34717282 -8.417473372 0.826276039 0.992272338 0.893909242 0.167689614 0.064892174 0.521458483 0.744565025 0.024845458 0.013643847 3.82E-09 8.417473372 -0.098363095 S(ph)NSRLEDQVIGVALQASK ddPTM_HeLa_Curcumin_4h_R1 1 SNSRLEDQVIGVALQASK 18 1 A0A3B3IRW6;Q2KHR3-2;Q2KHR3 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 0 S(0.5)NS(0.5)RLEDQVIGVALQASK 83.727 0.0022239 14392000 1829.7 1355.1 1637.3 1856.6 1376.3 1592.3 1702.2 3977.9 1568.7 1443.2 TRUE FALSE FALSE 1684.877314 1472.228806 1697.979778 1848.917881 1359.888521 1262.039031 1749.959151 5190.743398 1396.617535 1493.351093 1.128252641 0.98585578 1.137026508 1.238099929 0.910628805 0.845105372 1.17183371 3.475902903 0.935223834 1 10.54433767 -4.262298842 5.120705959 1.050839155 3.585725385 0.976148905 0.114411308 0.016137026 1.380402458 0.015468003 0.14381529 5.47E-05 4.262298842 2.53488623 up AKT(ph)QTPPVS(ph)PAPQPTEER ddPTM_HeLa_Curcumin_4h_R1 2 AKTQTPPVSPAPQPTEER 18 1 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 2 0 AKT(0.979)QT(0.021)PPVS(1)PAPQPTEER;AKT(0.924)QT(0.352)PPVS(0.725)PAPQPTEER ; 104.45 0.0016542 232143000 7627.5 6894.5 6520.2 6685.5 6688.6 7628.7 7399.2 14360 7599.7 6709.2 TRUE FALSE FALSE 7023.775326 7490.429859 6761.844348 6657.837172 6608.842813 6046.421627 7606.801638 18738.29789 6766.031924 6942.344201 1.01172963 1.078948211 0.974000158 0.959018594 0.951961272 0.87094812 1.095710817 2.699131209 0.974603351 1 12.76120718 -4.262253548 4.777507186 0.993786335 2.794221961 0.990020932 0.051553886 0.01181684 0.76178529 0.007200461 0.070500584 5.47E-05 4.262253548 1.800435626 up FKVQGEAVSNIQENTQTPT(ph)VQEESEEEEVDETGVEVK ddPTM_HeLa_Curcumin_4h_R1 1 FKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVK 37 1 F8VZJ2;F8W0W4;H0YHX9;Q13765;E9PAV3-2;E9PAV3 F8VZJ2 NACA "Nascent polypeptide-associated complex subunit alpha;Nascent polypeptide-associated complex subunit alpha, muscle-specific form" 1 0 FKVQGEAVSNIQENT(0.016)QT(0.083)PT(0.451)VQEES(0.451)EEEEVDETGVEVK 118.93 3.02E-19 2953300 712.87 489.4 816.61 745.52 590.46 528.49 726.09 450.9 753.15 613.76 TRUE FALSE FALSE 656.4455873 531.7015553 846.874285 742.4352358 583.4191501 418.8752167 746.4621312 588.3773343 670.5313293 635.0881143 1.033629149 0.837209111 1.333475255 1.16902713 0.918642842 0.659554489 1.175367818 0.926449923 1.055808342 1 9.31081296 -5.62790944 22.19098408 1.037660858 0.919564099 0.14699889 0.167271695 8.390165179 1741.470596 0.023820612 0.047641243 2.36E-06 5.62790944 -0.118096759 FLADEDREPGS(ph)SASSDTEEDSLPANK ddPTM_HeLa_Curcumin_4h_R1 1 FLADEDREPGSSASSDTEEDSLPANK 26 1 Q8N344 Q8N344 MIER2 Mesoderm induction early response protein 2 1 0 FLADEDREPGS(0.462)S(0.462)AS(0.025)S(0.035)DT(0.012)EEDS(0.004)LPANK 63.398 0.0010173 3788400 713.94 761.33 911 882.27 786.1 530.36 565.85 291.2 913.77 792.31 TRUE FALSE FALSE 657.4308957 827.1359728 944.7624614 878.6194005 776.7262709 420.3573576 581.7262281 379.9855395 813.5317171 819.8427135 0.801898809 1.008895925 1.152370383 1.071692638 0.947408885 0.512729272 0.709558332 0.463485902 0.992302186 1 9.679203346 -5.267553281 24.39824914 0.946312336 0.576687876 0.755307991 0.110684555 167.0149984 666495.2557 0.018817388 0.043123412 5.40E-06 5.267553281 -0.369624459 FLALVTMNQS(ph)GWGT(ph)S(ph)GRR ddPTM_HeLa_Curcumin_4h_R1 1 FLALVTMNQSGWGTSGRR 18 1 G3V1S7;M0R2V0;Q92839 G3V1S7 HAS1 Hyaluronan synthase 1 3 0 FLALVT(0.231)MNQS(0.772)GWGT(0.999)S(0.999)GRR 51.798 0.0081801 0 0 0 143.39 0 60.742 114.62 122.11 238.04 168.53 113.33 TRUE FALSE FALSE 0 0 148.7041595 0 60.01769132 90.84651997 125.536078 310.6173002 150.0426806 117.2682091 0 0 1.26806882 0 0.511798481 0.774690095 1.070503924 2.648776703 1.279483006 1 6.873668147 -3.981697361 1.34850893 0.495400651 4.94439166 0.624665169 0.472699952 1.1646654 1.126794394 0.069315377 8.451605212 0.000104304 3.981697361 4.448991009 FLAVGLVDNTVR ddPTM_HeLa_Curcumin_4h_R1 2 FLAVGLVDNTVR 12 0 Q15393 Q15393 SF3B3 Splicing factor 3B subunit 3 0 0 ; ; 121.6 2.07E-06 771730 590.705 309.54 486.75 582.415 441.8 936.06 491.076 764.52 756.017 693.62 FALSE FALSE TRUE 543.9500759 336.2952583 504.7893832 580.005121 436.5318235 741.9106044 504.8542709 997.6186286 673.0838266 717.7232434 0.757882765 0.468558405 0.703320379 0.808118068 0.608217482 1.033700122 0.703410786 1.38997676 0.937804137 1 9.487283833 -1.44107013 14.83654413 0.845517516 1.423924634 0 0.247413139 0 0 0.031662131 0 0.036218451 1.44107013 0.578407118 FLCADYAEQDELDYHR ddPTM_HeLa_Curcumin_4h_R1 1 FLCADYAEQDELDYHR 16 0 S4R3H4;E7EQT4;Q9UKV3;G3V3B0;Q9UKV3-3;Q9UKV3-2;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 0 0 156.96 0.0002352 7335600 6921.5 5850.1 5928.4 6015.4 5960.1 7788.3 5873 6279.3 6645.8 6039.8 FALSE FALSE TRUE 6373.655971 6355.756576 6148.111719 5990.509869 5889.0297 6172.918788 6037.780574 8193.829664 5916.772367 6249.6826 1.019836747 1.016972698 0.983747834 0.958530257 0.942292605 0.987717166 0.966093954 1.311079328 0.946731657 1 12.60956721 -4.258024478 24.99631043 0.996873091 1.311079446 0.913369172 0.030179347 69.3011562 507245.3827 0.004196175 0.040832656 5.52E-05 4.258024478 0.314206355 FLDDLGNAK ddPTM_HeLa_Curcumin_4h_R1 1 FLDDLGNAK 9 0 O95816-2;O95816 O95816-2 BAG2 BAG family molecular chaperone regulator 2 0 0 96.668 0.013341 1141000 1249.2 909.64 1032.1 1349.7 1026.7 1075.4 1183.2 1197.6 1296.9 1094.7 FALSE FALSE TRUE 1150.324502 988.2652283 1070.350534 1344.115299 1014.457273 852.3499177 1216.397408 1562.742727 1154.633315 1132.740744 1.015523198 0.872454914 0.944921016 1.186604531 0.895577632 0.752466902 1.07385332 1.379612004 1.01932708 1 10.14560199 -4.311697325 3.904471671 0.982839911 1.399597207 0.561819739 0.109673238 0.122560244 3.439077785 0.014937887 0.129495539 4.88E-05 4.311697325 0.416757296 FLDELDAVQMD ddPTM_HeLa_Curcumin_4h_R1 1 FLDELDAVQMD 11 0 A0A2R8YEY5;E7EQB9;O15160 A0A2R8YEY5 POLR1C DNA-directed RNA polymerases I and III subunit RPAC1 0 0 104.17 0.0060902 0 2252.6 1617.3 1687.4 1641.4 1890.6 2356.8 1874.1 2179.5 1925.9 1865.2 FALSE FALSE TRUE 2074.304333 1757.092205 1749.936528 1634.608322 1868.05583 1867.973113 1926.682202 2844.019517 1714.633588 1930.015561 1.074760419 0.910403129 0.906695554 0.846940488 0.967896771 0.967853913 0.998272885 1.473573361 0.888404023 1 10.91439676 -4.26148374 8.734609752 0.995577342 1.476058639 0.801146732 0.075205071 0.032021796 42.54493363 0.011528468 0.090308707 5.48E-05 4.26148374 0.480481298 FLDGIYVSEK ddPTM_HeLa_Curcumin_4h_R1 2 FLDGIYVSEK 10 0 H0Y9R4;H0Y9V9;D6RAN4;A0A2R8Y5Y7;P32969 H0Y9R4 RPL9 60S ribosomal protein L9 0 0 ; ; 135.55 1.95E-11 1889000 2216.15 1758.7 2181.5 2175.7 2281.65 2597.17 1720.07 1413.77 1663.2 1371.93 FALSE FALSE TRUE 2040.739389 1910.714191 2262.348309 2166.69753 2254.442814 2058.487666 1768.330535 1844.821965 1480.751121 1419.604465 1.437540835 1.345948282 1.593646938 1.526268466 1.588078136 1.450043104 1.245650164 1.299532377 1.043073023 1 10.4712733 -9.086428533 0.698321182 0.975001544 1.445226625 0.69136445 0.11039312 0.390118462 0.320534631 0.105569872 0.025883753 8.20E-10 9.086428533 0.47022508 FLEESVSMS(ph)PEER ddPTM_HeLa_Curcumin_4h_R1 2 FLEESVSMSPEER 13 0 A0A087WTB8;Q5TBK7;P15374 A0A087WTB8 UCHL3 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase isozyme L3 1 0 FLEES(0.034)VS(0.034)MS(0.933)PEER;FLEESVSMS(1)PEER ; 249.28 3.04E-28 55018000 3218.6 2926.1 2914.4 3156.1 3023.5 3886 2762.6 3101.4 3221.8 2792.9 TRUE FALSE FALSE 2963.844414 3179.019046 3022.410228 3143.040894 2987.446737 3079.999796 2840.111121 4047.002583 2868.376601 2889.953067 1.025568355 1.100024454 1.045833672 1.087575065 1.033735382 1.065761182 0.982753372 1.400369656 0.992533973 1 11.49683035 -4.257089384 24.99765384 1.02900349 1.400369803 0.891033865 0.038017746 103.9947061 597592.9335 0.005501138 0.05811019 5.53E-05 4.257089384 0.371366313 FLEMCNDLLAR ddPTM_HeLa_Curcumin_4h_R1 2 FLEMCNDLLAR 11 0 P34932;A0A087WYC1;A0A087WTS8 P34932 HSPA4 Heat shock 70 kDa protein 4 0 0 ; ; 162.64 0.001584 24949000 2111.6 1551.52 1744.08 1734.68 1675.37 3895.1 2591.95 2578.2 2363.9 1940.55 FALSE FALSE TRUE 1944.464632 1685.626475 1808.717139 1727.502354 1655.392307 3087.212353 2664.673141 3364.281311 2104.586084 2007.983968 0.968366612 0.839462118 0.900762739 0.860316806 0.824405141 1.537468626 1.327039052 1.675452277 1.048109008 1 10.97153204 -5.256250488 24.99774798 0.948191942 1.494691929 0.866510288 0.106208809 114.1961864 550143.4031 0.014612581 0.03605375 5.54E-06 5.256250488 0.546499987 FLESAAADFS(ph)DEDEDDDVDGR ddPTM_HeLa_Curcumin_4h_R1 1 FLESAAADFSDEDEDDDVDGR 21 0 O43815-2;O43815 O43815-2 STRN Striatin 1 0 FLESAAADFS(1)DEDEDDDVDGR 169.41 7.54E-09 1920500 1185.5 1108.9 1167.1 1377.6 1184.5 1124.5 1097.9 1096.7 1255.3 1080.4 TRUE FALSE FALSE 1091.666424 1204.748375 1210.353753 1371.899856 1170.375611 891.2660243 1128.704119 1431.078781 1117.596731 1117.94382 0.976494887 1.077646617 1.082660623 1.227163505 1.046900203 0.797236863 1.009625081 1.280099014 0.999689529 1 10.12663197 -7.260883938 24.25656951 0.988900363 1.066445462 0.08500867 0.1217965 68.84190486 3006338.993 0.020961731 0.024867046 5.48E-08 7.260883938 0.077545099 FLESAAADFS(ph)DEDEDDDVDGREK ddPTM_HeLa_Curcumin_4h_R1 8 FLESAAADFSDEDEDDDVDGREK 23 1 O43815-2;O43815 O43815-2 STRN Striatin 1 0 FLES(0.004)AAADFS(0.996)DEDEDDDVDGREK;FLESAAADFS(1)DEDEDDDVDGREK;FLESAAADFS(1)DEDEDDDVDGREK;FLES(0.106)AAADFS(0.894)DEDEDDDVDGREK;FLES(0.005)AAADFS(0.995)DEDEDDDVDGREK;FLESAAADFS(1)DEDEDDDVDGREK;FLES(0.001)AAADFS(0.999)DEDEDDDVDGREK;FLES(0.038)AAADFS(0.962)DEDEDDDVDGREK ;;;;;;; 152.4 4.49E-07 562974200 12418.41 10806.95 10996.51 11674.26 10718.78 13345.98 9833.74 8748.94 13488.8 11699.38 TRUE FALSE FALSE 11435.47974 11741.0546 11404.05033 11625.95501 10590.96555 10577.87331 10109.64828 11416.45153 12009.11239 12105.93258 0.944617828 0.969859573 0.942021629 0.960351871 0.87485747 0.873775997 0.835098676 0.943046019 0.992002252 1 13.5634266 -5.792927617 4.861836416 0.96980835 0.877343704 0.66606185 0.029951395 0.088843299 5.025743288 0.004707021 0.008942573 1.61E-06 5.792927617 -0.092464646 FLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL ddPTM_HeLa_Curcumin_4h_R1 6 FLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL 40 2 P07237;H7BZ94;H0Y3Z3 P07237 P4HB Protein disulfide-isomerase 0 0 ;;;;; ;;;;; 142.18 3.58E-25 80772300 35419.6 24744.9 30318 33368.1 29918.4 37098.5 26978.1 19650.8 34483.2 29570 FALSE FALSE TRUE 32616.10129 26883.73889 31441.61175 33230.03164 29561.64262 29403.85291 27735.03288 25642.23846 30700.47923 30597.5553 1.065970826 0.878623754 1.027585748 1.086035512 0.96614394 0.960987001 0.906446041 0.838048603 1.003363796 1 14.90112877 -4.565875962 0.979372462 1.022114175 0.791909358 0.488998677 0.054342049 0.760785257 0.762792826 0.008781561 0.163846317 2.72E-05 4.565875962 -0.230204817 FLET(ph)DS(ph)EEEQEEVNEKK ddPTM_HeLa_Curcumin_4h_R1 1 FLETDSEEEQEEVNEKK 17 1 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101 Q76FK4-2 NOL8 Nucleolar protein 8 2 0 FLET(1)DS(1)EEEQEEVNEKK 80.142 0.0069994 14718000 3649.6 3257.5 3019.5 3187.2 3426.9 4161.6 3190.7 1597.7 3269.4 3142.8 TRUE FALSE FALSE 3360.730309 3539.063785 3131.405326 3174.012211 3386.036456 3298.437249 3280.222455 2084.831375 2910.755 3252.012066 1.03343107 1.088268959 0.962913194 0.976014894 1.041212759 1.014275834 1.008674749 0.64108968 0.895062792 1 11.66711689 -4.261325591 6.422479375 1.016244629 0.633219149 0.819212034 0.050519113 0.023084611 5.513018707 0.004558398 0.038254187 5.48E-05 4.261325591 -0.383025481 FLGDIEVWDQAEK ddPTM_HeLa_Curcumin_4h_R1 1 FLGDIEVWDQAEK 13 0 P26639;P26639-2 P26639 TARS "Threonine--tRNA ligase, cytoplasmic" 0 0 193.23 4.99E-05 9876700 1600.5 858 904.35 1303.1 1321.6 2427.6 1627.9 1491 1725.9 1282.9 FALSE FALSE TRUE 1473.818736 932.1616968 937.8660065 1297.708117 1305.840783 1924.088395 1673.574493 1945.599036 1536.573088 1327.48068 1.110237429 0.702203589 0.706500683 0.977572132 0.983698523 1.449428549 1.260714765 1.465632658 1.157510698 1 10.37447515 -5.267343333 24.56180611 0.990009124 1.378804276 0.632808288 0.15247528 212.3995359 883633.3022 0.023607252 0.054145476 5.40E-06 5.267343333 0.388795152 FLGSDEEDKDSLQELS(ph)TEQK ddPTM_HeLa_Curcumin_4h_R1 2 FLGSDEEDKDSLQELSTEQK 20 1 Q99567;J3KMX1 Q99567 NUP88 Nuclear pore complex protein Nup88 1 0 FLGSDEEDKDSLQELS(0.755)T(0.245)EQK;FLGSDEEDKDSLQELS(0.738)T(0.262)EQK ; 104.3 0.00015911 48348000 4305 3072.2 3467.2 3867.1 3712.6 4616.7 3392 2439.8 4103.8 3312.9 TRUE FALSE FALSE 3964.254707 3337.747279 3595.697482 3851.098965 3668.32967 3659.144379 3487.170391 3183.683789 3653.623407 3428.023028 1.156425927 0.973665361 1.048912873 1.123416889 1.07010065 1.067421178 1.017254074 0.928722988 1.065810637 1 11.74316109 -4.337409998 1.974208232 1.069557243 0.899759198 0.399073391 0.049968251 0.607536835 2.822435761 0.009188508 0.175643031 4.60E-05 4.337409998 -0.169798045 FLIATGERPR ddPTM_HeLa_Curcumin_4h_R1 4 FLIATGERPR 10 1 E2QRB9;E9PIR7;F8W809;A0A087WSW9;A0A182DWI3;A0A087WSY9;Q16881-7;Q16881-5;Q16881-2;Q16881-4;Q16881-3;Q16881-6;Q16881;E9PKD3 E2QRB9 TXNRD1 "Thioredoxin reductase 1, cytoplasmic" 0 0 ;;; ;;; 146.79 5.33E-06 85034400 11622.2 9201.8 9613.1 10297.3 10421.5 14184.1 11031.8 11245.3 11285.5 10111 FALSE FALSE TRUE 10702.29061 9997.16259 9969.369943 10254.6925 10297.23042 11242.15777 11341.32262 14673.9402 10047.50888 10462.3565 1.022933085 0.955536412 0.95287997 0.980151317 0.984217124 1.074534 1.084012251 1.402546377 0.960348549 1 13.35292021 -3.614073823 1.176848969 0.999299362 2.557018989 0.937659959 0.031993467 1.051411258 0.403855988 0.004851659 2.919541218 0.000243179 3.614073823 1.557719628 FLIPNASQAESK ddPTM_HeLa_Curcumin_4h_R1 2 FLIPNASQAESK 12 0 P63104;E7EX29;E7ESK7;B0AZS6;P63104-2 P63104 YWHAZ 14-3-3 protein zeta/delta 0 0 ; ; 234.67 1.05E-38 14858800 13969.3 11218.3 11074.8 10672.4 11600.4 12269.1 10844.4 11304.9 12236.9 10656.6 FALSE FALSE TRUE 12863.61516 12187.95986 11485.24183 10628.24044 11462.07281 9724.350359 11148.66468 14751.71197 10894.54269 11026.91606 1.166565076 1.105291797 1.041564275 0.963845229 1.039463142 0.881873981 1.01104104 1.337791264 0.987995431 1 13.42874174 -6.641308234 6.704392679 1.08276135 1.032167481 0 0.120223659 0.689251625 38.07020455 0.01942687 0.02751177 2.28E-07 6.641308234 -0.050593869 FLIVAHDDGR ddPTM_HeLa_Curcumin_4h_R1 4 FLIVAHDDGR 10 0 Q16658 Q16658 FSCN1 Fascin 0 0 ;;; ;;; 111.61 0.0013846 248575000 26715.5 17897 22624.3 18604.3 21288.9 35839 26163 25073.5 21928.8 20795.3 FALSE FALSE TRUE 24600.93998 19443.93693 23462.77646 18527.32034 21035.04377 28405.58741 26897.06337 32718.29473 19523.2655 21517.93513 1.143276055 0.903615371 1.09038234 0.861017576 0.977558657 1.320088905 1.249983477 1.520512751 0.907301997 1 14.39325202 -5.188762547 4.942382709 1.037228427 1.360190717 0.696767797 0.111156032 0.107063575 4.91677986 0.015572065 0.040806316 6.47E-06 5.188762547 0.32296229 DTYSDRS(ph)GS(ph)SSPDSEITELK ddPTM_HeLa_Curcumin_4h_R1 1 DTYSDRSGSSSPDSEITELK 20 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 2 0 DT(0.148)Y(0.181)S(0.146)DRS(0.683)GS(0.387)S(0.153)S(0.184)PDS(0.099)EIT(0.02)ELK 80.859 0.0018917 7087000 2379.6 2396.8 1780.1 2213.7 2183.9 2373.1 2122.1 3168.9 1933.2 1655.8 TRUE FALSE FALSE 2191.252149 2603.968712 1846.072072 2204.540296 2157.858419 1880.89231 2181.640415 4135.083022 1721.132797 1713.338927 1.278936768 1.519821135 1.077470454 1.28669247 1.259446327 1.097793484 1.273326824 2.413464702 1.004548936 1 10.74259485 -4.262184935 4.288027419 1.176593566 2.506244578 0.855734815 0.14974486 0.060045597 2.55911075 0.02252049 0.242723029 5.47E-05 4.262184935 1.329651012 up FLLSLPEHR ddPTM_HeLa_Curcumin_4h_R1 1 FLLSLPEHR 9 0 Q15008;Q15008-4;C9J7B7 Q15008 PSMD6 26S proteasome non-ATPase regulatory subunit 6 0 0 96.665 0.012042 6234000 4116.6 3472.6 3683.7 3430.3 4192.8 5588.6 4090.2 3756.1 4552.9 4031.7 FALSE FALSE TRUE 3790.766766 3772.75607 3820.221163 3416.106328 4142.803598 4429.461363 4204.960004 4901.317599 4053.458261 4171.801275 0.908664271 0.904347025 0.915724626 0.818856437 0.993049123 1.061762311 1.0079483 1.174868426 0.971632634 1 12.02645472 -5.354581417 3.332001265 0.938608243 1.076448887 0.573474878 0.060847682 0.171963726 3.621350664 0.009640075 0.023619079 4.42E-06 5.354581417 0.137840645 FLMECRNS(ph)PVTK ddPTM_HeLa_Curcumin_4h_R1 1 FLMECRNSPVTK 12 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 0 FLMECRNS(0.921)PVT(0.079)K 146.67 0.0073789 262630000 2464 1890.3 1795 2096.2 1766.9 2451.7 1607.3 1258 2099.3 1702.5 TRUE FALSE FALSE 2268.9718 2053.689109 1861.524279 2087.52648 1745.830872 1943.189784 1652.396512 1641.558409 1869.012042 1761.661748 1.287972451 1.165768123 1.056686552 1.184975766 0.991013668 1.103043638 0.937976041 0.931823836 1.06093695 1 10.78272123 -4.858381832 0.882930607 1.137784519 0.88668945 0.373986376 0.086265592 1.066486986 1.035070734 0.018723169 0.211153194 1.39E-05 4.858381832 -0.251095069 FLMPEAYPS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 FLMPEAYPSSPR 12 0 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 FLMPEAYPS(0.5)S(0.5)PR;FLMPEAYPS(0.5)S(0.5)PR ; 130.69 0.0023832 38016000 4247.9 3047.9 3206.8 3733.4 3611.4 4031.8 3295.1 2071.39 3552.3 2963.8 TRUE FALSE FALSE 3911.674233 3311.346895 3325.646829 3717.95218 3568.336414 3195.559232 3387.551638 2702.947275 3162.621577 3066.791829 1.275493888 1.079742962 1.084405794 1.212326231 1.163540472 1.041987657 1.104591321 0.881359879 1.031247556 1 11.58251453 -3.532756428 1.188352131 1.131415767 9.33E-18 0.397217522 0.082331464 6.824657246 2.257506353 0.015755764 14.58189587 0.000293254 3.532756428 -1.131415767 FLMPEAYPS(ph)SPRK ddPTM_HeLa_Curcumin_4h_R1 1 FLMPEAYPSSPRK 13 1 O43166-3;O43166-2;O43166 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 FLMPEAY(0.001)PS(0.5)S(0.5)PRK 69.045 0.017382 26943000 1476.8 1024.3 1227.3 1058.8 1004.9 1580.6 1106.9 666.97 1422.9 1050.6 TRUE FALSE FALSE 1359.909722 1112.835928 1272.784818 1054.418966 992.9172238 1252.765743 1137.956635 870.3260826 1266.81143 1087.108272 1.2509423 1.023666139 1.170798577 0.969930037 0.913356332 1.152383599 1.046773964 0.800588226 1.165303827 1 10.08627992 -6.250717646 24.11928367 1.116455038 0.986756123 0.308886451 0.108148761 567.5473674 1276735.226 0.018934812 0.031174564 5.61E-07 6.250717646 -0.129698915 FLNAENAQK ddPTM_HeLa_Curcumin_4h_R1 2 FLNAENAQK 9 0 P43487-2;P43487;F6WQW2;C9JXG8;C9JGV6 P43487-2 RANBP1 Ran-specific GTPase-activating protein 0 0 ; ; 136.57 0.0002432 8193400 5278.9 4302.4 5315.9 5167.8 5537.8 6285.1 4893.6 4327.2 5808.9 4975.2 FALSE FALSE TRUE 4861.069495 4674.280285 5512.91193 5146.417013 5471.765352 4981.499412 5030.901246 5646.54336 5171.678203 5148.08783 0.944247584 0.907964363 1.070865943 0.999675449 1.062873349 0.96764072 0.977236872 1.096823432 1.004582356 1 12.32982095 -6.752997282 24.99999312 0.968008739 1.024216977 0.316103259 0.046350223 197.5575442 585034.5846 0.007304858 0.010233118 1.77E-07 6.752997282 0.056208239 FLPISS(ph)TPQPER ddPTM_HeLa_Curcumin_4h_R1 1 FLPISSTPQPER 12 0 J3KNG6;Q08AE8-4;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8 J3KNG6 SPIRE1 Protein spire homolog 1 1 0 FLPIS(0.086)S(0.457)T(0.457)PQPER 96.067 0.011499 5382000 1177.6 1067.1 959.98 1084.5 1092.6 1557 1413.8 1120.8 1397.5 1102 TRUE FALSE FALSE 1084.391717 1159.335369 995.5577033 1080.012626 1079.571459 1234.060649 1453.467423 1462.52676 1244.197746 1140.294418 0.950975205 1.016698276 0.87307075 0.947134888 0.946747999 1.082229843 1.274642233 1.282586968 1.091119738 1 10.15519065 -4.896899638 2.662245669 0.967641039 1.288274405 0.830159182 0.054226023 0.055942115 0.783173937 0.005770187 0.022433897 1.27E-05 4.896899638 0.320633365 FLPISS(ph)TPQPERR ddPTM_HeLa_Curcumin_4h_R1 1 FLPISSTPQPERR 13 1 J3KNG6;Q08AE8-4;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8 J3KNG6 SPIRE1 Protein spire homolog 1 1 0 FLPIS(0.184)S(0.525)T(0.291)PQPERR 94.532 0.0046148 25689000 1835.4 1360.8 1550.6 1827.4 1358.4 1930.7 1564.8 477.64 1881.2 1926.9 TRUE FALSE FALSE 1690.126153 1478.421488 1608.0666 1819.838703 1342.201967 1530.251057 1608.704077 623.2702372 1674.837067 1993.859632 0.847665566 0.741487247 0.806509433 0.912721575 0.673167733 0.767481839 0.806829152 0.312594842 0.83999748 1 10.96134813 -3.359920395 0.216553495 0.987317124 2.88E-28 0.49426537 0.124461141 10.44897006 0.300956506 0.105901169 2.953038102 0.000436596 3.359920395 -0.987317124 FLPISST(ph)PQPER ddPTM_HeLa_Curcumin_4h_R1 3 FLPISSTPQPER 12 0 J3KNG6;Q08AE8-4;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8 J3KNG6 SPIRE1 Protein spire homolog 1 1 0 FLPIS(0.027)S(0.182)T(0.791)PQPER;FLPIS(0.095)S(0.172)T(0.733)PQPER;FLPIS(0.037)S(0.256)T(0.706)PQPER ;; 138.89 0.0038433 76303900 8600.8 7481.1 8110.3 8814.3 8531.2 10581.4 7332.2 3307.08 9180 7815.6 TRUE FALSE FALSE 7920.037604 8127.732949 8410.874853 8777.828762 8429.471012 8386.698363 7537.921798 4315.393468 8172.976967 8087.191518 0.979331031 1.005013042 1.040024195 1.085398898 1.042323654 1.037034716 0.932081524 0.533608417 1.01060757 1 12.98142306 -4.265367469 3.126278615 1.007472248 0.46380745 0.954100833 0.032033313 0.062666274 0.933121807 0.005459461 0.082977098 5.43E-05 4.265367469 -0.543664798 FLPISST(ph)PQPERR ddPTM_HeLa_Curcumin_4h_R1 1 FLPISSTPQPERR 13 1 J3KNG6;Q08AE8-4;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8 J3KNG6 SPIRE1 Protein spire homolog 1 1 0 FLPIS(0.066)S(0.404)T(0.53)PQPERR 77.324 0.013184 27181000 1999.4 1948.4 1719.2 2069.6 1546.4 2033.2 1841.3 896.6 2221.2 1872.3 TRUE FALSE FALSE 1841.14538 2116.811014 1782.915064 2061.036544 1527.96019 1611.491401 1892.961922 1169.969213 1977.539917 1937.362286 0.950336132 1.092625282 0.920279639 1.063836412 0.788680672 0.83179662 0.977082055 0.603898002 1.020738316 1 10.91987805 -3.375420445 0.598189072 0.983073236 9.20E-17 0.550049167 0.093889987 5.074017211 0.576125436 0.0155752 4.399687812 0.000421288 3.375420445 -0.983073236 FLPLNIRNS(ph)PFTR ddPTM_HeLa_Curcumin_4h_R1 2 FLPLNIRNSPFTR 13 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;H3BSK8 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 0 FLPLNIRNS(0.982)PFT(0.018)R;FLPLNIRNS(0.992)PFT(0.008)R ; 77.387 0.010971 144941000 4457.7 3687.8 4483.7 3860.5 3380.8 5771.3 7004.5 5932.7 4488.8 3634.1 TRUE FALSE FALSE 4104.868341 4006.556999 4649.869866 3844.526274 3340.486168 4574.267324 7201.027418 7741.552919 3996.38987 3760.384705 1.091608616 1.065464657 1.236541001 1.022375788 0.888336282 1.216435999 1.914970936 2.058713011 1.06276091 1 11.87666455 -4.776209623 3.34554801 1.049827005 2.034399316 0.952389549 0.082699606 0.032918003 0.752007417 0.012066159 0.048034034 1.67E-05 4.776209623 0.984572311 FLPS(ph)PVVIK ddPTM_HeLa_Curcumin_4h_R1 2 FLPSPVVIK 9 0 Q13618;H7C399;A0A087WTG3;Q13618-3;Q13618-2 Q13618 CUL3 Cullin-3 1 0 FLPS(1)PVVIK;FLPS(1)PVVIK ; 124.67 0.0050262 36016000 8226.1 6995.7 7396.7 8075 8288.5 8601.1 6699.8 3313.4 8138.1 7159 TRUE FALSE FALSE 7574.995505 7600.377136 7670.828209 8041.58779 8189.665051 6817.134906 6887.778356 4323.640407 7245.370791 7407.774717 1.022573687 1.026000037 1.035510461 1.085560522 1.105549961 0.920267579 0.929803972 0.583662513 0.978076557 1 12.85482451 -3.926535019 1.355589264 1.023303582 0.030172722 0.892108526 0.046010632 0.630642855 0.554766449 0.006631929 1.067439097 0.000118431 3.926535019 -0.99313086 FLPSELRDEH ddPTM_HeLa_Curcumin_4h_R1 2 FLPSELRDEH 10 1 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 ; ; 128.91 0.0026514 34466000 5815.9 3960.6 3956.8 5225.1 4721.8 6542.7 4849.3 4724.7 5765.7 5137.3 FALSE FALSE TRUE 5355.565378 4302.936616 4103.442489 5203.479921 4665.495619 5185.670269 4985.358307 6165.23928 5133.217135 5315.820793 1.00747666 0.809458555 0.771930178 0.978866693 0.877662322 0.975516382 0.937834156 1.159790655 0.965649019 1 12.37607675 -4.257339156 23.63446211 0.960030312 1.15979083 0.355807729 0.083549748 196.6238455 1133273.092 0.013164512 0.133594965 5.53E-05 4.257339156 0.199760517 FLQDYFDGNLKR ddPTM_HeLa_Curcumin_4h_R1 1 FLQDYFDGNLKR 12 1 P30101 P30101 PDIA3 Protein disulfide-isomerase A3 0 0 136.93 0.0023129 21595000 2947.2 2211.5 2207.2 2532.6 1746.6 2578.2 1770.8 1457.7 2588.8 2331.2 FALSE FALSE TRUE 2713.92601 2402.652206 2289.000774 2522.120772 1725.772936 2043.452258 1820.483882 1902.14602 2304.815117 2412.209026 1.125079121 0.996038146 0.948923061 1.045564768 0.715432583 0.847129015 0.754695742 0.788549416 0.95547902 1 11.23613921 -5.770008228 24.99926192 1.045165923 0.779946071 0.770873157 0.061264479 59.72921677 174257.908 0.009749362 0.01787585 1.70E-06 5.770008228 -0.265219852 FLQEEAEK ddPTM_HeLa_Curcumin_4h_R1 2 FLQEEAEK 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 141.48 0.00059532 8518000 4926.7 3534.1 4082.6 4310.5 4007.4 4785.9 3767.5 3262.3 4182.7 4403.8 FALSE FALSE TRUE 4536.746496 3839.571856 4233.904747 4292.664293 3959.614372 3793.250392 3873.20591 4256.960252 3723.868275 4556.831722 0.995592283 0.842596806 0.929133443 0.942028268 0.868940223 0.832431528 0.849977824 0.93419299 0.817205572 1 12.15381538 -7.276866638 23.92536765 0.997918587 0.885400561 0 0.068066508 197.316112 306007.0135 0.006447695 0.007389591 5.29E-08 7.276866638 -0.112518026 FLQEHGSDS(ph)FLAEHK ddPTM_HeLa_Curcumin_4h_R1 1 FLQEHGSDSFLAEHK 15 0 Q00688 Q00688 FKBP3 Peptidyl-prolyl cis-trans isomerase FKBP3 1 0 FLQEHGSDS(1)FLAEHK 153.25 0.00019214 8324800 2056.5 1635.3 1401.3 1244 2473 3606.6 2085.2 1347.6 2466.7 1797.1 TRUE FALSE FALSE 1893.725855 1776.648045 1453.233411 1238.852658 2443.51109 2858.550505 2143.7051 1758.477036 2196.109181 1859.549091 1.01837906 0.955418738 0.781497739 0.666211322 1.314034193 1.537227771 1.152809092 0.945647009 1.180990161 1 10.86073712 -5.721276723 24.99913335 0.964106458 1.252799611 0.372186946 0.190374793 132.5942717 82532.29116 0.027133381 0.054266191 1.90E-06 5.721276723 0.288693153 FLSHS(ph)TDSLNK ddPTM_HeLa_Curcumin_4h_R1 4 FLSHSTDSLNK 11 0 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2;A0A087WY36 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 FLSHS(0.977)T(0.023)DSLNK;FLS(0.075)HS(0.884)T(0.041)DSLNK;FLS(0.306)HS(0.664)T(0.029)DSLNK;FLS(0.001)HS(0.819)T(0.021)DS(0.158)LNK ;;; 202.65 3.27E-07 86022600 23382.7 18950.7 16503.3 15963 26160.6 35883.7 17656.7 6046.41 27825.1 18171.4 TRUE FALSE FALSE 21531.93462 20588.71407 17114.92682 15896.94934 25848.65193 28441.01613 18152.09948 7889.932575 24772.75614 18802.8548 1.145141781 1.094978092 0.910230228 0.845454028 1.374719542 1.512590319 0.965390611 0.419613546 1.317499731 1 14.1986641 -4.296776707 4.155209779 1.094033701 0.384601294 0.523135146 0.203655036 0.122766398 4.3582942 0.027549124 0.238073069 5.05E-05 4.296776707 -0.709432408 TS(ph)TSDLSR ddPTM_HeLa_Curcumin_4h_R1 1 TSTSDLSR 8 0 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 0 T(0.023)S(0.924)T(0.041)S(0.012)DLSR 122.96 0.0073495 13452000 3806.6 3384.2 3933.2 3855.7 4122.3 3913.6 2222.5 1007.3 4046.2 3709.5 TRUE FALSE FALSE 3505.303593 3676.715168 4078.967852 3839.746135 4073.144265 3101.875245 2284.857368 1314.421133 3602.341983 3838.404849 0.913218832 0.957875814 1.06267265 1.000349438 1.06115546 0.808115706 0.595262214 0.342439421 0.938499748 1 11.90629117 -4.640888145 1.740543371 0.97501573 0.322731633 0.940539202 0.053391963 0.088842992 0.430019149 0.008704481 0.075125705 2.29E-05 4.640888145 -0.652284097 down FLVHNVK ddPTM_HeLa_Curcumin_4h_R1 4 FLVHNVK 7 0 D3YTB1;F8W727;P62910 D3YTB1 RPL32 60S ribosomal protein L32 0 0 ;;; ;;; 113.25 0.011389 35440700 33653.1 26251 29941.9 26917.7 28634.2 41858.7 31826.6 29122.6 30578.1 28070.8 FALSE FALSE TRUE 30989.42162 28520.01947 31051.57315 26806.32169 28292.75587 33176.73378 32719.56874 38001.94668 27223.75893 29046.25821 1.066898924 0.981882735 1.069038667 0.922883818 0.97405854 1.142203362 1.126464156 1.308325031 0.937255282 1 14.8260647 -4.321149794 1.217436858 1.021362294 1.408031537 0.72657238 0.058091894 0.533818531 0.703903916 0.008017503 0.251889056 4.77E-05 4.321149794 0.386669242 FLVTVIK ddPTM_HeLa_Curcumin_4h_R1 2 FLVTVIK 7 0 O14980 O14980 XPO1 Exportin-1 0 0 ; ; 121.29 0.0094017 3395600 7697.5 6041.7 6800.6 6211.8 6525.6 7360.5 6575.8 4392.3 6374.7 6641.6 FALSE FALSE TRUE 7088.234753 6563.917627 7052.636218 6186.097218 6447.786482 5833.84933 6760.29925 5731.49205 5675.411359 6872.395106 1.031406758 0.955113541 1.026226826 0.900137015 0.938215336 0.848881538 0.983688968 0.833987564 0.82582728 1 12.74659727 -6.25777024 24.82959815 1.010555825 0.904750946 0.034046886 0.073137858 143.1035258 968399.5699 0.006038324 0.009766883 5.52E-07 6.25777024 -0.105804879 FMERDPDELR ddPTM_HeLa_Curcumin_4h_R1 1 FMERDPDELR 10 1 A0A087WTB8;Q5TBK7;P15374 A0A087WTB8 UCHL3 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase isozyme L3 0 0 145.46 0.00097497 22168000 8101.1 6085.4 6427.4 7139.9 7067.5 7576.5 5807.8 6069.9 8255 6967.4 FALSE FALSE TRUE 7459.889387 6611.39486 6665.605098 7110.356986 6983.224678 6005.048495 5970.751237 7920.584568 7349.447153 7209.516631 1.034728092 0.917037188 0.924556449 0.986246006 0.968612049 0.83293358 0.828176359 1.098629072 1.019409141 1 12.81568682 -7.259702756 24.91893437 1.016399377 0.931119097 0.203720123 0.07321011 160.2954844 2300090.646 0.011934016 0.014217658 5.50E-08 7.259702756 -0.08528028 FMET(ph)T(ph)MNK ddPTM_HeLa_Curcumin_4h_R1 1 FMETTMNK 8 0 Q6ZN66-2;Q6ZN66 Q6ZN66-2 GBP6 Guanylate-binding protein 6 2 0 FMET(1)T(1)MNK 57.047 0.0076253 0 1004.4 758.1 759.36 865.35 940.6 936.74 621.34 720.57 1400.4 831.96 TRUE FALSE FALSE 924.9006802 823.626786 787.5025496 861.769411 929.3839593 742.4495648 638.7731281 940.2684759 1246.779624 860.8705481 1.074378351 0.956737093 0.914774645 1.001044132 1.079586195 0.862440429 0.742008342 1.092229811 1.448277707 1 9.749652501 -5.759498475 0.733809044 1.028821643 0.897509754 0.118476453 0.166108353 1.034558195 0.984211816 0.01884615 0.074571014 1.74E-06 5.759498475 -0.131311889 FMQASEDLLK ddPTM_HeLa_Curcumin_4h_R1 1 FMQASEDLLK 10 0 Q32Q12;P22392-2;J3KPD9;E7ERL0;E5RHP0;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 0 150.61 0.0039188 17663000 1189.9 1105.6 1195.5 925.07 1033.5 2118.6 1627.3 1227 1187.7 782.85 FALSE FALSE TRUE 1095.718159 1201.163138 1239.806282 921.2423055 1021.176188 1679.178478 1672.957658 1601.106652 1057.412281 810.0539792 1.352648327 1.482818637 1.530523043 1.137260391 1.260627333 2.072921708 2.065242195 1.97654316 1.305360271 1 9.661874237 -1 0.199063437 1.016070773 6.431600667 0.632969934 0.224333164 22.17129517 0.253758846 0.22241347 37.6858215 0.1 1 5.415529894 FMQASEDLLKEHYVDLK ddPTM_HeLa_Curcumin_4h_R1 3 FMQASEDLLKEHYVDLK 17 1 Q32Q12;P22392-2;J3KPD9;E7ERL0;E5RHP0;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 0 ;; ;; 113.67 0.0004347 27346800 15260 12935.5 13901 12781.5 11167.1 35978.6 22923.9 19348 17618.6 15459.4 FALSE FALSE TRUE 14052.1549 14053.58698 14416.18329 12728.61354 11033.93963 28516.2328 23567.08294 25247.11613 15685.88366 15996.613 0.878445637 0.878535161 0.901202229 0.795706787 0.689767242 1.782641913 1.473254553 1.57827886 0.980575304 1 13.96547885 -5.259800363 24.99999455 0.907367303 1.597578074 0.900102124 0.112045273 34.32293844 523523.0252 0.016636948 0.04010268 5.50E-06 5.259800363 0.69021077 FMS(ph)SPVLSDLPR ddPTM_HeLa_Curcumin_4h_R1 2 FMSSPVLSDLPR 12 0 E9PJV4;E9PLJ6;E9PL62;E9PP25;E9PS02;E9PP62;E9PIU0;Q6MZQ0-4;Q6MZQ0 E9PJV4 PRR5L Proline-rich protein 5-like 1 0 FMS(0.971)S(0.029)PVLSDLPR;FMS(0.956)S(0.044)PVLSDLPR ; 114.76 0.0041632 18144000 2347.69 1875.4 1693.64 2046.68 1878.19 3380.9 2076.76 2480.8 2387.79 1997 TRUE FALSE FALSE 2161.867859 2037.501219 1756.407788 2038.21138 1855.793811 2679.663229 2135.028296 3237.1845 2125.855411 2066.395601 1.046202314 0.986017013 0.849986221 0.986360685 0.89808254 1.296781327 1.033213725 1.566585071 1.02877465 1 11.01290076 -1.290537741 0.945469928 1.002806403 199.9999999 0.703833292 0.108644884 251.1255767 0.790178668 0.015619643 107571.2844 0.051222676 1.290537741 198.9971935 FNAHGDANTIVCNSK ddPTM_HeLa_Curcumin_4h_R1 2 FNAHGDANTIVCNSK 15 0 P09382 P09382 LGALS1 Galectin-1 0 0 ; ; 194.67 1.20E-12 52619000 17214.9 13447.9 15961.4 14347.6 15590.9 22049 16417.5 15704.3 17218.2 14614.2 FALSE FALSE TRUE 15852.3225 14610.27655 16552.94353 14288.23343 15404.9887 17475.78886 16878.13086 20492.46878 15329.40654 15122.04236 1.048292428 0.966157626 1.094623539 0.944861355 1.018710855 1.15565004 1.116127733 1.355138961 1.01371271 1 13.88436538 -2.68257427 0.742449541 1.01813687 4.506187258 0.809318679 0.049590415 6.740535084 0.405681586 0.007651301 32.8216681 0.002076949 2.68257427 3.488050387 FNDEHIPDSPFVVPVASLSDDAR ddPTM_HeLa_Curcumin_4h_R1 2 FNDEHIPDSPFVVPVASLSDDAR 23 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 0 0 ; ; 95.344 9.71E-05 17085900 3590.4 3196.4 2930.5 3080.4 3511 4520.8 3261.1 3309.6 3603.8 2883.6 FALSE FALSE TRUE 3306.216051 3472.682573 3039.106908 3067.654121 3469.133618 3583.13512 3352.597689 4318.681804 3208.472156 2983.804885 1.108053703 1.163843719 1.018534061 1.028101447 1.162654313 1.200861068 1.123598163 1.447374064 1.075295564 1 11.54293748 -1 0.5802085 1.05690523 20.47859948 0.728546442 0.064044712 57.16439352 0.434804311 0.012413828 1403.685929 0.1 1 19.42169425 RSS(ph)TSSEPTPTVK ddPTM_HeLa_Curcumin_4h_R1 1 RSSTSSEPTPTVK 13 1 F8WAN1;A0A494C1J1;Q69YQ0-2;Q69YQ0 F8WAN1 SPECC1L-ADORA2A;SPECC1L Cytospin-A 1 0 RS(0.05)S(0.821)T(0.102)S(0.026)S(0.001)EPTPTVK 128.71 0.0027389 15639000 4060.1 3406.4 3712 3826.1 3771.3 4033.1 3902.5 8024.7 4868.9 3753.6 TRUE FALSE FALSE 3738.738801 3700.834037 3849.569985 3810.268612 3726.329711 3196.589598 4011.993647 10471.39409 4334.793851 3884.037321 0.962590854 0.95283174 0.9911259 0.981007209 0.959395959 0.823006921 1.032944155 2.696007588 1.116053604 1 11.92334135 -4.262021536 5.620490439 0.968842811 2.754079502 0.983323452 0.067083566 0.008691818 1.112012879 0.006729236 0.059320823 5.47E-05 4.262021536 1.785236691 up FNDEHIPESPYLVPVIAPSDDAR ddPTM_HeLa_Curcumin_4h_R1 2 FNDEHIPESPYLVPVIAPSDDAR 23 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3 O75369-8 FLNB Filamin-B 0 0 ; ; 103.35 2.23E-05 80265000 8960.8 8432.1 8524.9 8476.6 8976.8 11208.9 9145 8894.4 10340.6 8888.1 FALSE FALSE TRUE 8251.543225 9160.933151 8840.840293 8441.526075 8869.757523 8884.04779 9401.584087 11606.26162 9206.262051 9196.960813 0.89720326 0.996082656 0.961278456 0.917860394 0.964422672 0.965976475 1.02224901 1.261967062 1.001011338 1 13.16694148 -4.171275432 1.900267605 0.953104899 1.409628353 0.878008727 0.033201219 0.296794146 0.909537128 0.00569575 0.256903246 6.74E-05 4.171275432 0.456523454 FNDEHIPESPYLVPVIAPSDDARR ddPTM_HeLa_Curcumin_4h_R1 1 FNDEHIPESPYLVPVIAPSDDARR 24 1 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3 O75369-8 FLNB Filamin-B 0 0 89.756 1.92E-05 5936500 3006.4 2464.4 2596.6 2812.1 2661.9 3818.1 2615.8 2636.5 3592.1 3064.3 FALSE FALSE TRUE 2768.440268 2677.411755 2692.83228 2800.464275 2630.158581 3026.183021 2689.192308 3440.356713 3198.055617 3170.784197 0.873109015 0.844400498 0.849263814 0.883208727 0.829497821 0.954395769 0.848115842 1.085017617 1.008600844 1 11.63062398 -9.230900542 0.992967107 0.999249387 0.890124194 0.258651984 0.072157911 0.57805681 1.033427919 0.043683582 0.012428687 5.88E-10 9.230900542 -0.109125193 FNDFDHR ddPTM_HeLa_Curcumin_4h_R1 1 FNDFDHR 7 0 Q9NWH9;Q9NWH9-3;H7C3F4;H0YMM0 Q9NWH9 SLTM SAFB-like transcription modulator 0 0 118.74 0.010133 9017200 8239.2 6727.5 7511.6 7836.4 7779.7 9759.4 8198.2 6527.4 8339 6944.4 FALSE FALSE TRUE 7587.058626 7308.995123 7789.986504 7803.975053 7686.932159 7735.190429 8428.219428 8517.574212 7424.232563 7185.717383 1.055852634 1.01715594 1.084093082 1.086039798 1.069751529 1.076467389 1.172912735 1.185347789 1.033192953 1 12.81091648 -1 0.242012741 1.010613068 2.103281548 0.834195992 0.023387137 13.50225558 0.166968742 0.014698859 6.009557107 0.1 1 1.09266848 FNDS(ph)EGDDTEET(ph)EDYR ddPTM_HeLa_Curcumin_4h_R1 1 FNDSEGDDTEETEDYR 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 0 FNDS(1)EGDDT(0.318)EET(0.682)EDYR 183.71 4.23E-05 66361000 2326.9 1677 1875.4 1850.5 1888.2 2310.8 1979.1 2263 1671.3 1456.6 TRUE FALSE FALSE 2142.72341 1821.952407 1944.903974 1842.843121 1865.684448 1831.514032 2034.62822 2952.978282 1487.962571 1507.216742 1.421642522 1.208819115 1.290394354 1.222679573 1.237834212 1.21516301 1.349924111 1.959226036 0.987225347 1 10.55767118 -1 0.034117168 7.13E-12 3.364779439 0.448033633 0.191442798 869.22876 2.291521327 68.2802615 184.6967065 0.1 1 3.364779439 FNDS(ph)EGDDTEETEDY(ph)RQFR ddPTM_HeLa_Curcumin_4h_R1 1 FNDSEGDDTEETEDYRQFR 19 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 0 FNDS(0.968)EGDDT(0.043)EET(0.082)EDY(0.907)RQFR 101.89 0.0017018 23875000 1904.5 1067.2 1258.5 1517 1226 2112.1 1599.5 1915.5 2052.1 1622.1 TRUE FALSE FALSE 1753.756815 1159.444013 1305.141117 1510.723056 1211.380751 1674.026652 1644.377665 2499.527132 1826.989764 1678.467854 1.044855766 0.690775227 0.777578858 0.900060762 0.721718172 0.997354014 0.979689698 1.489171881 1.088486598 1 10.71292919 -4.256631815 4.358422399 0.950250486 1.530470042 0.609101044 0.135895823 0.129656122 5.828033926 0.020709523 0.232771545 5.54E-05 4.256631815 0.580219557 FNDS(ph)EGDDTEETEDYR ddPTM_HeLa_Curcumin_4h_R1 3 FNDSEGDDTEETEDYR 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 FNDS(1)EGDDTEETEDYR;FNDS(0.511)EGDDT(0.457)EET(0.032)EDYR;FNDS(0.958)EGDDT(0.025)EET(0.016)EDYR ;; 231.86 5.55E-22 65789000 6149.97 5913.45 6273 5953.44 6551.59 6761.28 5793.17 5510.29 6645.69 6086.33 TRUE FALSE FALSE 5663.193385 6424.582268 6505.482898 5928.806243 6473.466568 5358.914313 5955.710759 7190.352055 5916.674434 6297.829514 0.899229389 1.020126419 1.032972214 0.94140469 1.027888506 0.850914478 0.94567672 1.14171907 0.939478343 1 12.62063899 -7.237798237 24.81742328 0.95241387 0.987729338 0.073141618 0.075043418 2056.753059 2159089.66 0.012959571 0.015866263 5.78E-08 7.237798237 0.035315468 FNDS(ph)EGDDTEETEDYRQFR ddPTM_HeLa_Curcumin_4h_R1 4 FNDSEGDDTEETEDYRQFR 19 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 FNDS(0.999)EGDDT(0.001)EETEDYRQFR;FNDS(0.999)EGDDT(0.001)EETEDYRQFR;FNDS(0.997)EGDDT(0.002)EETEDYRQFR;FNDS(1)EGDDTEETEDYRQFR ;;; 157.7 1.17E-05 952873600 3917.82 2725.81 2555.93 3210.9 2710.13 3251.26 2586.31 2467.86 4475.9 3300.42 TRUE FALSE FALSE 3607.720413 2961.41687 2650.655014 3197.614147 2677.81347 2576.912027 2658.874898 3220.299153 3984.904968 3415.109349 1.056399677 0.867151405 0.776155239 0.936313839 0.78410768 0.754562084 0.778562156 0.942956381 1.166845498 1 11.73771606 -7.165225583 4.507053791 1.026536285 0.825945136 0.660283747 0.076923341 0.09397622 3.271816243 0.010486925 0.012887139 6.84E-08 7.165225583 -0.200591149 FNDSEGDDT(ph)EET(ph)EDYR ddPTM_HeLa_Curcumin_4h_R1 1 FNDSEGDDTEETEDYR 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 0 FNDS(0.05)EGDDT(0.994)EET(0.955)EDY(0.001)R 123.63 0.0025807 35283000 2186.7 2306.6 2182.8 2327.4 2437.3 2540.2 2140.3 2426.1 2180.8 2122.7 TRUE FALSE FALSE 2013.620388 2505.972226 2263.696488 2317.769835 2408.236789 2013.333886 2200.351058 3165.806722 1941.571696 2196.463667 0.916755609 1.140912214 1.030609576 1.055227942 1.096415491 0.916625172 1.001769841 1.441319868 0.883953477 1 11.10096692 -4.262110693 6.51338503 0.990789926 1.450140946 0.732965732 0.078687092 0.044347398 11.41253775 0.010871921 0.089725716 5.47E-05 4.262110693 0.45935102 FNDSEGDDT(ph)EETEDYR ddPTM_HeLa_Curcumin_4h_R1 2 FNDSEGDDTEETEDYR 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 FNDSEGDDT(1)EETEDYR;FNDSEGDDT(0.924)EET(0.076)EDYR ; 369.44 1.12E-195 1765610000 2814.51 2433.16 2286.86 2524.66 2893.12 2681.57 2579.9 2655.83 2369.2 1867.78 TRUE FALSE FALSE 2591.738564 2643.471508 2371.613043 2514.213626 2858.621434 2125.382154 2652.285051 3465.580341 2109.304687 1932.685216 1.341003978 1.367771371 1.227107769 1.300891426 1.479093134 1.099704254 1.372331629 1.793142677 1.091385534 1 10.91639096 -12.72466747 0.130997267 2.02E-22 1.543678428 0.442317236 0.161069214 45.01133111 0.511534957 12.45992303 0.615304702 1.89E-13 12.72466747 1.543678428 FNEEHIPDSPFVVPVAS(ph)PSGDARR ddPTM_HeLa_Curcumin_4h_R1 2 FNEEHIPDSPFVVPVASPSGDARR 24 1 P21333-2;P21333;H0Y5C6;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 FNEEHIPDSPFVVPVAS(0.776)PS(0.224)GDARR;FNEEHIPDSPFVVPVAS(0.609)PS(0.391)GDARR ; 65.817 0.0015243 18041200 5207.2 4105.4 3886.7 5256.8 4231.4 4967.5 3493.1 4015.1 5486.1 5270 TRUE FALSE FALSE 4795.044625 4460.252483 4030.744521 5235.048754 4180.943319 3937.184505 3591.106985 5239.285507 4884.288556 5453.132108 0.879319358 0.817924891 0.739161356 0.960007689 0.766704939 0.72200424 0.658540251 0.960784629 0.895684986 1 12.41286939 -8.080587428 0.421672166 1.012965764 0.775604731 0.230182911 0.096957258 0.750995022 0.325880918 0.073443953 0.039484126 8.31E-09 8.080587428 -0.237361033 FNEEHIPDSPFVVPVASPS(ph)GDAR ddPTM_HeLa_Curcumin_4h_R1 2 FNEEHIPDSPFVVPVASPSGDAR 23 0 P21333-2;P21333;H0Y5C6;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 FNEEHIPDS(0.201)PFVVPVAS(0.319)PS(0.479)GDAR;FNEEHIPDS(0.001)PFVVPVAS(0.42)PS(0.579)GDAR ; 103.64 1.30E-05 424780000 5592.1 4517.1 4132.7 5326.5 4556.7 6325.4 4704.6 3740.1 5590.8 5000 TRUE FALSE FALSE 5149.479384 4907.537996 4285.861497 5304.460354 4502.364329 5013.440738 4836.598414 4880.439273 4977.503227 5173.749628 0.995308964 0.948545707 0.828385949 1.025264216 0.870232356 0.96901495 0.934834262 0.943307973 0.962068825 1 12.33699452 -7.19801744 4.44888448 0.997890361 0.929449821 0.186552993 0.051100762 0.191188151 7.651416118 0.007538449 0.009202469 6.34E-08 7.19801744 -0.06844054 FNEEHIPDSPFVVPVASPSGDAR ddPTM_HeLa_Curcumin_4h_R1 3 FNEEHIPDSPFVVPVASPSGDAR 23 0 P21333-2;P21333;H0Y5C6;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ;; ;; 98.887 6.22E-05 68505000 5260.62 4975.81 5605.18 6024.7 5905.46 7593.9 5329.64 4874.87 6647.2 5855.1 FALSE FALSE TRUE 4844.236376 5405.896845 5812.912902 5999.771388 5835.041246 6018.839539 5479.175354 6361.195422 5918.01879 6058.564289 0.79956837 0.892273579 0.959453861 0.990295902 0.963106269 0.993443207 0.904368608 1.049950965 0.976802178 1 12.56476024 -6.668548664 4.773299056 0.901781685 0.975566919 0.173047571 0.060961242 0.304038938 11.97104335 0.012751447 0.018092134 2.15E-07 6.668548664 0.073785234 FNFESFPES(ph)PGEK ddPTM_HeLa_Curcumin_4h_R1 1 FNFESFPESPGEK 13 0 H0YBR0;Q96Q05-3;Q96Q05;Q96Q05-2 H0YBR0 TRAPPC9 Trafficking protein particle complex subunit 9 1 0 FNFESFPES(1)PGEK 109.83 0.0042197 0 1600.1 1232.5 1609.3 1488.4 1678.9 1745.6 1818.2 1675.2 1390.4 1476.4 TRUE FALSE FALSE 1473.450397 1339.031808 1668.942074 1482.241395 1658.880214 1383.542883 1869.213799 2185.960768 1237.876599 1527.70479 0.964486337 0.876499057 1.092450639 0.97024072 1.08586438 0.905634971 1.223543849 1.430879043 0.810285211 1 10.57715007 -4.531851449 3.237014409 0.985441296 1.41416333 0.752885544 0.086229283 0.065885902 1.339447508 0.008500273 0.05086661 2.94E-05 4.531851449 0.428722034 FNGGHS(ph)PTHSPEK ddPTM_HeLa_Curcumin_4h_R1 1 FNGGHSPTHSPEK 13 0 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 0 FNGGHS(0.52)PT(0.48)HSPEK 118.55 0.0012478 81492000 4577.7 3443.7 3773.5 3438.9 4421.1 4390.5 3143.4 5950.1 4995.9 3989.2 TRUE FALSE FALSE 4215.370215 3741.358083 3913.34923 3424.670743 4368.38127 3479.860809 3231.595344 7764.258099 4447.862269 4127.824403 1.021208705 0.9063753 0.948041595 0.829655142 1.058276914 0.843025398 0.782881012 1.88095649 1.077531851 1 12.01116588 -4.254301852 24.99989526 0.96786495 1.880956914 0.890351612 0.098569417 198.6060028 695619.8199 0.013447363 0.182892089 5.57E-05 4.254301852 0.913091964 FNHDGEEEEEDDDYGSR ddPTM_HeLa_Curcumin_4h_R1 2 FNHDGEEEEEDDDYGSR 17 0 Q6PJT7;Q6PJT7-5;H0YJA2;Q6PJT7-9;Q6PJT7-2;Q6PJT7-3;Q6PJT7-11;Q6PJT7-4;G3V256;Q6PJT7-10;G3V5I6 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 0 0 ; ; 193.3 1.18E-07 25219000 3910.2 3437.2 4305.8 4533.9 4023.5 4885.4 3657.3 3050.3 4087.1 3741 FALSE FALSE TRUE 3600.703544 3734.296252 4465.376736 4515.139923 3975.52239 3872.11297 3759.913995 3980.322428 3638.755355 3870.999472 0.930174124 0.964685291 1.153546201 1.166401586 1.027001533 1.000287651 0.971303154 1.028241532 0.940004095 1 11.9184904 -6.890153852 22.1339253 0.965913863 1.055158321 0.388264488 0.060603609 3.952109818 778.262081 0.011073425 0.014553346 1.29E-07 6.890153852 0.089244458 FNLTYVSHDGDDK ddPTM_HeLa_Curcumin_4h_R1 2 FNLTYVSHDGDDK 13 0 P26639;P26639-2 P26639 TARS "Threonine--tRNA ligase, cytoplasmic" 0 0 ; ; 148.85 0.00048182 66944000 12739.5 8066.7 11897.2 11028.1 13401.9 16083.3 10409.3 10849.3 10680.8 8049.7 FALSE FALSE TRUE 11731.15513 8763.949603 12338.1207 10982.46864 13242.0911 12747.44228 10701.35694 14157.20163 9509.142962 8329.426476 1.408398906 1.052167233 1.481268937 1.318514387 1.589796264 1.530410566 1.28476516 1.699661035 1.141632379 1 13.02400145 -12.15784752 0.136966832 1.92E-12 1.629338411 0.516128724 0.154421812 27.74108109 0.382702509 8.372745967 0.514661037 6.95E-13 12.15784752 1.629338411 FNNY(ph)GILSES(ph)PLTS(ph)QR ddPTM_HeLa_Curcumin_4h_R1 1 FNNYGILSESPLTSQR 16 0 A8MTZ0-4 A8MTZ0-4 3 0 FNNY(1)GILS(0.163)ES(0.612)PLT(0.442)S(0.783)QR 50.87 0.009637 0 172.83 0 274.84 68.074 146.25 177.37 150.22 216.46 58.712 0 TRUE FALSE FALSE 159.1503231 0 285.0258122 67.79232783 144.5060643 140.5814626 154.4347689 282.4576575 52.27144049 0 0 FNPFVTSDR ddPTM_HeLa_Curcumin_4h_R1 2 FNPFVTSDR 9 0 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;Q9UNX3;P61254;J3QRC4;E5RHH1;J3KSS0 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 0 0 ; ; 108.98 0.0039553 9578400 3941.9 3366.6 3518 3906.8 3759.2 4056.7 3694.2 3338.9 3760.5 3325.2 FALSE FALSE TRUE 3629.894456 3657.593903 3648.380175 3890.634697 3714.373995 3215.294692 3797.84931 4356.91524 3347.982558 3440.750452 1.054971729 1.063022138 1.060344313 1.130751779 1.079524379 0.934474829 1.103785166 1.266268885 0.973038471 1 11.74850755 -4.34126026 3.508783483 1.037569947 1.276775359 0.622498315 0.053692133 0.119113449 2.403739543 0.00726397 0.064651626 4.56E-05 4.34126026 0.239205413 FNRDVDETISWIK ddPTM_HeLa_Curcumin_4h_R1 2 FNRDVDETISWIK 13 1 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 ; ; 98.253 0.006845 18367600 4494.1 3419.3 3881.1 3451.5 4789.3 4416.6 3764.2 3923.6 3337.1 3818.1 FALSE FALSE TRUE 4138.387243 3714.849056 4024.93698 3437.218608 4732.190725 3500.547375 3869.813321 5119.887578 2971.028479 3950.778691 1.047486475 0.940282751 1.01877055 0.870010415 1.19778684 0.886039854 0.979506478 1.295918597 0.75201086 1 11.94792132 -4.258035738 24.76233393 1.007413959 1.295918721 0.367193913 0.119230517 169.9952276 1236692.09 0.010864426 0.105230947 5.52E-05 4.258035738 0.288504763 GNDT(ph)PLALESTNTEK ddPTM_HeLa_Curcumin_4h_R1 2 GNDTPLALESTNTEK 15 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 GNDT(1)PLALESTNTEK;GNDT(1)PLALESTNTEK ; 186.17 5.35E-05 9825700 2769.7 2253.1 2795.6 2857.4 2974.2 3023.6 3080.2 4488.6 2823.1 2391.2 TRUE FALSE FALSE 2550.475322 2447.847924 2899.207395 2845.576836 2938.734608 2396.471277 3166.622122 5857.153477 2513.412993 2474.294022 1.030789106 0.989311659 1.171731156 1.150056061 1.187706304 0.968547495 1.279808339 2.367201887 1.015810155 1 11.27280123 -4.26201312 2.865645731 1.044150729 2.601681022 0.96078074 0.078471789 0.057286899 0.653894604 0.011864045 0.206411078 5.47E-05 4.26201312 1.557530293 up FNVS(ph)TGNTRAALAT(ph)LER ddPTM_HeLa_Curcumin_4h_R1 2 FNVSTGNTRAALATLER 17 1 C9JVJ9;Q8N434-2;Q8N434 C9JVJ9 SVOPL Putative transporter SVOPL 2 0 FNVS(0.999)T(0.001)GNTRAALAT(1)LER;FNVS(0.999)T(0.001)GNTRAALAT(1)LER ; 112.57 0.0042912 2190935000 6132 5012.3 5187.3 5480.2 4815.5 5891.1 4439.9 3831.4 6151.1 5316.5 TRUE FALSE FALSE 5646.64573 5445.540878 5379.545901 5457.524384 4758.078308 4669.219454 4564.471645 4999.576222 5476.339719 5501.247979 1.026429957 0.989873734 0.977877369 0.992052059 0.864908894 0.848756404 0.829715668 0.908807645 0.995472253 1 12.42554322 -5.779701181 4.112921038 1.00751456 0.857963103 0.890333064 0.022886867 0.045368731 1.719993828 0.003516385 0.006847846 1.66E-06 5.779701181 -0.149551457 FNVWDTAGQEK ddPTM_HeLa_Curcumin_4h_R1 2 FNVWDTAGQEK 11 0 F5H018;B5MDF5;J3KQE5;P62826;H0YFC6 F5H018 RAN GTP-binding nuclear protein Ran 0 0 ; ; 215.5 2.00E-30 5015400 3290.3 2323.86 2791.73 2642.15 2727.11 3227.9 3083.84 2290.97 2045.35 1523.44 FALSE FALSE TRUE 3029.869283 2524.724103 2895.19397 2631.217483 2694.590994 2558.397154 3170.364251 2989.476207 1820.980222 1576.379427 1.922043153 1.60159671 1.836609842 1.669152387 1.709354327 1.622957716 2.011168249 1.896419197 1.155166194 1 10.62239911 -9.342462263 0.829893904 0.945807472 1.787664211 0.809481397 0.136204773 0.225694098 0.248995815 0.127612062 0.0261027 4.55E-10 9.342462263 0.841856739 FNYSGS(ph)GGR ddPTM_HeLa_Curcumin_4h_R1 2 FNYSGSGGR 9 0 Q12906;Q12906-7 Q12906 ILF3 Interleukin enhancer-binding factor 3 1 0 FNYS(0.023)GS(0.977)GGR;FNYS(0.002)GS(0.998)GGR ; 105.13 0.010722 29008000 3532.1 2962.59 3224.7 3702.4 4263.7 6494.9 6047 3001.8 3954.9 3747 TRUE FALSE FALSE 3252.530558 3218.663079 3344.210219 3687.08045 4212.858162 5147.784527 6216.662545 3917.035001 3521.057365 3877.207971 0.838884729 0.830149711 0.862530523 0.950962775 1.086570077 1.327703999 1.603386404 1.01027209 0.908142506 1 11.92080241 -5.475862572 2.451644159 0.91049505 1.344017276 0.629564328 0.142229075 0.135320087 1.600274733 0.020508517 0.050699044 3.34E-06 5.475862572 0.433522226 FPEAEALS(ph)PEQAAHYLR ddPTM_HeLa_Curcumin_4h_R1 1 FPEAEALSPEQAAHYLR 17 0 Q2NKX8 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 0 FPEAEALS(1)PEQAAHYLR 91.964 0.0017475 5488600 1845.3 1917.3 1588.1 1575.8 2020.9 1528.8 1212.5 848.63 1734.9 1540.6 TRUE FALSE FALSE 1699.242558 2083.022869 1646.956383 1569.279757 1996.802087 1211.709647 1246.519487 1107.37338 1544.585811 1594.135735 1.065933421 1.306678486 1.033134348 0.984407866 1.252592262 0.760104438 0.781940621 0.694654386 0.968917374 1 10.63855876 -5.195938572 10.2937292 1.062304871 0.748564243 0.66825867 0.109365331 0.313808463 48.21890691 0.015105071 0.038557462 6.37E-06 5.195938572 -0.313740628 FPEFCSSPS(ph)PPVEVK ddPTM_HeLa_Curcumin_4h_R1 2 FPEFCSSPSPPVEVK 15 0 Q68E01-4;Q68E01-3;Q68E01-2;Q68E01 Q68E01-4 INTS3 Integrator complex subunit 3 1 0 FPEFCS(0.001)S(0.004)PS(0.995)PPVEVK;FPEFCS(0.175)S(0.023)PS(0.802)PPVEVK ; 146.2 0.00048051 50553000 4102 3118.8 3773.8 3792.5 3525.4 4539.4 3481.4 2576.7 3566.2 3452.8 TRUE FALSE FALSE 3777.322372 3388.375175 3913.660348 3776.80764 3483.361908 3597.87727 3579.078714 3362.323968 3174.996782 3572.784543 1.057248856 0.948384974 1.095409001 1.057104786 0.974971165 1.007023297 1.001761699 0.941093404 0.888661699 1 11.8028332 -2.52562691 0.715235459 1.026493594 4.75E-12 0 0.059054332 27.86020241 1.342185915 0.006696205 39.34538495 0.002981076 2.52562691 -1.026493594 FPKFS(ph)MPK ddPTM_HeLa_Curcumin_4h_R1 1 FPKFSMPK 8 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 FPKFS(1)MPK 97.602 0.0063851 0 1083.6 871.85 941.99 904.89 542.41 1163.7 595.29 692.93 1057.2 934.28 TRUE FALSE FALSE 997.8319166 947.2088291 976.9009781 901.1458049 535.942115 922.3355024 611.9922353 904.2011671 941.227805 966.7461605 1.032155034 0.979790629 1.01050412 0.932143143 0.554377288 0.954061718 0.633043357 0.935303603 0.973603872 1 9.916993319 -5.987203549 24.99175487 1.010263329 0.768998913 0.477287712 0.11371411 124.7759106 243688.5375 0.014382526 0.026059424 1.03E-06 5.987203549 -0.241264416 FPPEDFRHS(ph)PEDFR ddPTM_HeLa_Curcumin_4h_R1 1 FPPEDFRHSPEDFR 14 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 0 FPPEDFRHS(1)PEDFR 107.63 0.0014562 27813000 2968.2 2894 2451.4 2969.9 3299 3615.9 3110.4 2212 3130.9 2422.3 TRUE FALSE FALSE 2733.263838 3144.144465 2542.25104 2957.611341 3259.66158 2865.92158 3197.669453 2886.428617 2787.448103 2506.474745 1.0904813 1.254408995 1.014273551 1.179988487 1.300496479 1.143407324 1.275763683 1.151588949 1.112099018 1 11.29144398 -7.547417179 0.390453326 0.991038482 1.227091436 0.271819845 0.083679989 0.606070239 0.259205369 0.050695348 0.045056711 2.84E-08 7.547417179 0.236052954 FPS(ph)MCARLDT(ph)IIS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 FPSMCARLDTIISK 14 1 Q5TH74-2 Q5TH74-2 3 0 FPS(1)MCARLDT(1)IIS(1)K 58.63 0.0092434 0 2547.5 1991.8 2076.9 2178.4 2303.6 3134.1 2041.9 2003.1 2656 2171.8 TRUE FALSE FALSE 2345.862687 2163.962317 2153.871741 2169.386358 2276.131075 2484.052331 2099.190219 2613.835969 2364.643445 2247.269888 1.043872255 0.962929432 0.958439283 0.965343045 1.012842777 1.105364489 0.93410686 1.16311618 1.052229399 1 11.13395768 -4.241810475 24.16356601 1.010194956 1.163116404 0.47538796 0.049782546 1959.653044 2412313.657 0.006570216 0.320445185 5.73E-05 4.241810475 0.152921448 FPSGNQGGAGPSQGSGGGTGGSVYTEDNDDDLYG ddPTM_HeLa_Curcumin_4h_R1 2 FPSGNQGGAGPSQGSGGGTGGSVYTEDNDDDLYG 34 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 ; ; 95.963 7.16E-11 30467000 8029.4 6939 6248.3 7649 6759.5 9337.4 6706.5 6376.8 8181.5 7537.4 FALSE FALSE TRUE 7393.864517 7538.77624 6479.867495 7617.350465 6678.897377 7400.717986 6894.66634 8321.056965 7284.009919 7799.324089 0.948013499 0.966593535 0.830824238 0.976668026 0.856343101 0.948892225 0.884008186 1.066894627 0.933928355 1 12.92913339 -8.357407559 0.755367811 0.9950741 0.927828821 0.003395477 0.066198911 0.782834798 0.948604851 0.024706957 0.013474707 4.39E-09 8.357407559 -0.067245279 FPSSQELEDASCCS(ph)LK ddPTM_HeLa_Curcumin_4h_R1 1 FPSSQELEDASCCSLK 16 0 Q9Y4I5-3;Q9Y4I5-2;Q9Y4I5 Q9Y4I5-3 MTL5 Tesmin 1 0 FPSSQELEDASCCS(1)LK 77.204 0.015335 14663000 919.9 897.13 1147.9 938.54 767.65 870.88 929.84 643.61 1298.2 859.86 TRUE FALSE FALSE 847.0889443 974.6739197 1190.442184 934.6565702 758.4962751 690.2496712 955.9288079 839.8437262 1155.790708 889.740071 0.952063386 1.09545917 1.337966247 1.05048272 0.85249198 0.775788001 1.074391094 0.943920313 1.29902063 1 9.797240118 -2.75901084 11.11611595 0.995550293 0.151306159 0 0.173751509 0 0 0.019685887 0 0.001741763 2.75901084 -0.844244133 FQDGDLTLYQS(ph)NTILR ddPTM_HeLa_Curcumin_4h_R1 1 FQDGDLTLYQSNTILR 16 0 P09211;A8MX94;A0A087X2E9 P09211 GSTP1 Glutathione S-transferase P 1 0 FQDGDLT(0.002)LYQS(0.977)NT(0.021)ILR 137.73 3.21E-05 0 552.38 370.71 529.61 318.31 516.72 632.63 554.33 350.74 410.16 374.4 TRUE FALSE FALSE 508.6585401 402.7525205 549.2378125 316.9929176 510.5584515 501.4154068 569.8830079 457.6790114 365.1664742 387.4103721 1.312970888 1.039601801 1.417715818 0.818235495 1.317875019 1.294274606 1.471006067 1.181380377 0.942583112 1 8.597718769 -12.23158926 0.336921696 1.56E-08 1.255333835 0.251850959 0.179422586 25.66532768 0.760667828 17.22489188 0.061237309 5.87E-13 12.23158926 1.255333819 FQDGDLTLYQSNTILR ddPTM_HeLa_Curcumin_4h_R1 1 FQDGDLTLYQSNTILR 16 0 P09211;A8MX94;A0A087X2E9 P09211 GSTP1 Glutathione S-transferase P 0 0 167.03 0.0015291 26785000 1187.9 1156.1 1077.1 1045.8 1268.4 1573.6 1279.5 1035 1325 1379.7 FALSE FALSE TRUE 1093.876462 1256.028133 1117.018274 1041.472757 1253.275158 1247.217622 1315.399326 1350.566735 1179.650815 1427.644472 0.766210694 0.879790562 0.78242048 0.729504283 0.877862229 0.8736192 0.921377382 0.946010552 0.826291726 1 10.47942103 -3.072649527 13.57049126 0.873251886 44.1324395 0 0.081434579 0 0 0.013715831 0 0.000845961 3.072649527 43.25918761 FQELLAS(ph)PAYR ddPTM_HeLa_Curcumin_4h_R1 2 FQELLASPAYR 11 0 Q9NSI2-2;Q9NSI2 Q9NSI2-2 FAM207A Protein FAM207A 1 0 FQELLAS(1)PAYR;FQELLAS(0.997)PAY(0.003)R ; 121.45 0.0040106 22149800 2434.16 2097.77 2690.01 2856.61 2032.15 4972.9 4161.3 2300.45 2980.55 1849.95 TRUE FALSE FALSE 2241.493667 2279.091891 2789.704137 2844.790105 2007.917938 3941.464484 4278.054878 3001.846615 2653.591122 1914.235625 1.170960167 1.190601544 1.457346264 1.486123269 1.048939803 2.059027861 2.234863265 1.568169862 1.38624059 1 10.90255271 -5.544011871 0.527447151 1.057341664 2.11112244 0.460358512 0.285813192 0.723590045 0.289061549 0.060790996 0.374232716 2.86E-06 5.544011871 1.053780776 FQESEERPK ddPTM_HeLa_Curcumin_4h_R1 1 FQESEERPK 9 1 P34932 P34932 HSPA4 Heat shock 70 kDa protein 4 0 0 104.05 0.0026641 3840000 2551.5 2377.8 2020.8 2306.8 2914.7 2686.3 2295.6 2300 2615.7 2261.1 FALSE FALSE TRUE 2349.546083 2583.326437 2095.692626 2297.255073 2879.944106 2129.131099 2360.008358 3001.259412 2328.764254 2339.673057 1.004219831 1.104139926 0.895720289 0.981870123 1.230917327 0.910012231 1.008691514 1.28276872 0.995337467 1 11.19209123 -4.261280762 23.79286086 1.009877847 1.282768873 0.440850399 0.090485208 4.267489844 638918.6551 0.011389856 0.088402564 5.48E-05 4.261280762 0.272891026 FQETEFLS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 3 FQETEFLSPPR 11 0 P42166 P42166 TMPO "Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin" 1 0 FQETEFLS(1)PPR;FQET(0.001)EFLS(0.999)PPR;FQETEFLS(1)PPR ;; 149.82 0.00064798 112856000 4681 4064.3 4039.9 4865.3 4578.3 7326.5 5830.8 3076.42 5301.7 4234.1 TRUE FALSE FALSE 4310.493911 4415.599982 4189.622248 4845.168678 4523.706763 5806.901313 5994.396555 4014.406296 4720.116774 4381.23466 0.983853695 1.007843753 0.956265202 1.105891159 1.032518711 1.325402943 1.368198013 0.916272833 1.077348542 1 12.09712177 -5.39641281 5.518165132 1.000172752 1.218825126 0.307092716 0.120371959 0.156840516 6.405488068 0.015581931 0.035314399 4.01E-06 5.39641281 0.218652373 FQFDGDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 FQFDGDKK 8 1 P52209-2;P52209;K7ELN9 P52209-2 PGD "6-phosphogluconate dehydrogenase, decarboxylating" 0 1 ; FQFDGDK(1)K;FQFDGDK(1)K 104.01 0.0033118 12499900 5942.3 7484.1 5877 5767.4 12271.3 14123 11331.7 9778.1 14872.1 6129.3 FALSE TRUE FALSE 5471.960685 8130.992255 6094.80679 5743.536027 12124.97276 11193.7306 11649.637 12759.39768 13240.66784 6342.292719 0.862773279 1.282027276 0.960978476 0.905593022 1.911764925 1.764934401 1.836817933 2.011795772 2.087678451 1 12.63078875 -5.760850618 24.99999965 0.962889989 1.869835236 0.38282187 0.37625659 2.955503446 125486.1212 0.018865601 0.035990847 1.73E-06 5.760850618 0.906945247 FQGENTK(ac)SAAAR ddPTM_HeLa_Curcumin_4h_R1 1 FQGENTKSAAAR 12 1 M0R2F5;Q96CT7 M0R2F5 CCDC124 Coiled-coil domain-containing protein 124 0 1 FQGENTK(1)SAAAR 106.67 0.00017696 0 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 FQPGETLTEILETPATSEQEAEHQR ddPTM_HeLa_Curcumin_4h_R1 2 FQPGETLTEILETPATSEQEAEHQR 25 0 P46940;H0YLE8 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 0 ; ; 161.46 1.54E-09 3077600 992.3 635.96 943.35 796.22 1042.25 916.57 710.51 914.72 1054.86 810.87 FALSE FALSE TRUE 913.7584079 690.9295486 978.3113809 792.9254526 1029.821849 726.4630501 730.4449984 1193.613917 939.1444971 839.0476721 1.089042301 0.823468763 1.165978303 0.945030275 1.22736989 0.865818563 0.870564358 1.422581764 1.119298138 1 9.712608972 FQPPQVPDQAPAEAPTEKTEVS(ph)PVPR ddPTM_HeLa_Curcumin_4h_R1 4 FQPPQVPDQAPAEAPTEKTEVSPVPR 26 1 E9PPY3;O43159 E9PPY3 RRP8 Ribosomal RNA-processing protein 8 1 0 FQPPQVPDQAPAEAPT(0.045)EKT(0.21)EVS(0.745)PVPR;FQPPQVPDQAPAEAPT(0.214)EKT(0.141)EVS(0.645)PVPR;FQPPQVPDQAPAEAPT(0.162)EKT(0.202)EVS(0.636)PVPR;FQPPQVPDQAPAEAPT(0.005)EKT(0.003)EVS(0.992)PVPR ;;; 110.4 5.12E-08 79908000 13234.5 10123.5 10243.5 11123.3 8985.4 13402.4 8110.9 5727.13 14300.1 11899.7 TRUE FALSE FALSE 12186.97536 10998.53023 10623.13312 11077.27473 8878.254974 10622.59116 8338.470025 7473.305573 12731.41481 12313.21369 0.989747735 0.893229867 0.862742529 0.899624989 0.721034752 0.862698515 0.677196891 0.6069338 1.033963604 1 13.58791973 -3.302646765 0.271419539 1.02074849 7.46E-15 0.855716787 0.051787237 3.484083452 0.129120665 0.025554353 1.302032616 0.000498142 3.302646765 -1.02074849 FQPSSVLS(ph)PYER ddPTM_HeLa_Curcumin_4h_R1 1 FQPSSVLSPYER 12 0 J3QLM6;Q7Z6J9 J3QLM6 TSEN54 tRNA-splicing endonuclease subunit Sen54 1 0 FQPSSVLS(0.999)PYER 108.36 0.0051522 0 1149.3 1067.2 769.35 1034.7 967.09 1631.9 1320.3 1271.1 1075.9 1082.8 TRUE FALSE FALSE 1058.331692 1159.444013 797.8627878 1030.418686 955.5580834 1293.425545 1357.344065 1658.652539 957.8764618 1120.427219 0.944578705 1.034823139 0.712105859 0.919665881 0.852851543 1.154403894 1.21145224 1.480375084 0.854920735 1 10.12983322 -4.584597126 1.451501284 0.947951363 1.519617793 0.763512653 0.101181408 0.254985534 0.730000189 0.014477703 0.176412576 2.60E-05 4.584597126 0.57166643 FQSPQIQATIS(ph)PPLQPK ddPTM_HeLa_Curcumin_4h_R1 2 FQSPQIQATISPPLQPK 17 0 A0A087WYN9;Q7Z478 A0A087WYN9 DHX29 ATP-dependent RNA helicase DHX29 1 0 FQSPQIQAT(0.012)IS(0.988)PPLQPK;FQSPQIQAT(0.04)IS(0.96)PPLQPK ; 187.04 1.62E-06 211590000 4521.6 3646.3 3937.7 4208.1 3461.8 4362.1 2905.7 1862.35 4159.1 4108.2 TRUE FALSE FALSE 4163.710589 3961.469924 4083.634626 4190.687997 3420.520296 3457.351289 2987.226122 2430.171942 3702.857136 4250.959644 0.979475445 0.931900149 0.960638295 0.985821637 0.804646617 0.813310776 0.702718062 0.571676079 0.871063817 1 12.05357285 -3.864868993 0.482216558 0.994254495 0.085429714 0.854650973 0.050892159 0.857532409 0.102293575 0.006665988 0.480055262 0.000136499 3.864868993 -0.908824781 FQSQADQDQQASGLQS(ph)PPSR ddPTM_HeLa_Curcumin_4h_R1 4 FQSQADQDQQASGLQSPPSR 20 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 0 FQSQADQDQQAS(0.001)GLQS(0.995)PPS(0.005)R;FQSQADQDQQAS(0.001)GLQS(0.999)PPSR;FQSQADQDQQASGLQS(0.999)PPS(0.001)R;FQSQADQDQQASGLQS(1)PPSR ;;; 248.33 8.29E-50 44732000 3440.67 3659.66 3364.31 3341.84 4315.45 4577.82 3677.92 3114.9 3397.76 2798.34 TRUE FALSE FALSE 3168.337339 3975.984703 3488.994288 3328.012352 4263.991077 3628.328529 3781.112537 4064.618671 3025.034229 2895.582107 1.094197029 1.373121036 1.204937094 1.149341386 1.472585104 1.25305669 1.305821212 1.403731105 1.04470677 1 11.49963769 -7.32608117 0.556444131 1.00258646 1.343747741 0.604719228 0.09505931 0.321408372 0.229109847 0.032717802 0.036799966 4.72E-08 7.32608117 0.341161281 FRDQDLAS(ph)CDRDR ddPTM_HeLa_Curcumin_4h_R1 1 FRDQDLASCDRDR 13 2 Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q96HJ9-2 LUC7L2 Putative RNA-binding protein Luc7-like 2 1 0 FRDQDLAS(1)CDRDR 81.992 0.014571 16238000 1878.2 2106.6 2002.9 1976.4 2009.2 2546.3 2174.8 2800.5 2221.9 2029.2 TRUE FALSE FALSE 1729.538488 2288.685117 2077.129236 1968.22218 1985.241602 2018.168677 2235.819035 3654.359558 1978.163129 2099.714549 0.823701721 1.089998218 0.989243627 0.937376074 0.945481662 0.961163354 1.064820471 1.74040779 0.942110503 1 11.0359775 -4.224583919 2.537565217 0.938514486 1.958781165 0.925150365 0.065832793 0.132607814 0.984335679 0.011643357 0.300598933 5.96E-05 4.224583919 1.020266679 FRELAEEAAR ddPTM_HeLa_Curcumin_4h_R1 1 FRELAEEAAR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 113.67 0.0051968 10744000 3003.2 1885.9 2579.9 2260.8 2311.3 3147.9 2495.6 2125.6 2452.8 2521.1 FALSE FALSE TRUE 2765.493551 2048.908793 2675.513364 2251.445409 2283.739257 2494.990056 2565.619819 2773.685655 2183.733977 2608.708037 1.060100828 0.785411308 1.025608587 0.863049976 0.875429226 0.956408314 0.983482928 1.06324112 0.83709405 1 11.34911977 FRIDELEPR ddPTM_HeLa_Curcumin_4h_R1 2 FRIDELEPR 9 1 F5H6X6;Q14697;Q14697-2 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 0 ; ; 125.68 0.004108 29952000 6287.2 4632.6 5777.1 5660.1 5469.4 6091.1 4418.1 3347.4 4980.4 5142.6 FALSE FALSE TRUE 5789.561486 5033.021302 5991.204408 5636.680006 5404.180977 4827.737199 4542.059995 4368.00685 4434.06258 5321.304967 1.087996558 0.94582463 1.125890067 1.059266485 1.015574377 0.907246856 0.853561302 0.820852569 0.833266014 1 12.37756437 -5.112605501 1.959295392 1.042885352 0.832311068 0.399427881 0.080513214 0.128768052 0.939994436 0.007246666 0.026534247 7.72E-06 5.112605501 -0.210574284 FS(ph)EINPDMKK ddPTM_HeLa_Curcumin_4h_R1 1 FSEINPDMKK 10 1 P48960-2;P48960-3;P48960 P48960-2 CD97 CD97 antigen;CD97 antigen subunit alpha;CD97 antigen subunit beta 1 0 FS(1)EINPDMKK 99.442 0.020394 23906000 1638.5 1176.9 1069.7 1131.3 1502.1 1706 1253.4 1150.5 1336.6 1373.8 TRUE FALSE FALSE 1508.810996 1278.625992 1109.344023 1126.61898 1484.188439 1352.156369 1288.567031 1501.282154 1189.978324 1421.539448 1.06139228 0.899465712 0.780382159 0.792534447 1.044071229 0.951191591 0.906458862 1.056096021 0.837105383 1 10.47323842 -7.255917231 24.57923448 1.028990799 0.914047626 0 0.104917124 365.1395003 1625247.03 0.014990842 0.018080416 5.55E-08 7.255917231 -0.114943174 FS(ph)GGFGAR ddPTM_HeLa_Curcumin_4h_R1 1 FSGGFGAR 8 0 A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8Y5G6;A0A2R8YFR4;A0A0D9SFB3;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;A0A0D9SF53;A0A2R8YF78;F6S8Q4;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;O15523-2;O15523;A0A0J9YVQ7;A0A087WVZ1 A0A2R8YCW1 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 1 0 FS(1)GGFGAR 91.265 0.020166 40506000 1704.6 1467.9 1318.3 1685.4 1779.5 2863.9 2366 815.58 1474.9 1151.6 TRUE FALSE FALSE 1569.679111 1594.778735 1367.157358 1678.426261 1758.280625 2269.894857 2432.383592 1064.246588 1313.10716 1191.618014 1.317267021 1.338330502 1.147311757 1.408527096 1.475540487 1.904884644 2.041244395 0.893110523 1.101953096 1 10.21870612 -5.92399054 1.836580211 1.16870331 1.650453978 0.278604193 0.298884919 0.295981535 2.01091102 0.046046691 0.095747271 1.19E-06 5.92399054 0.481750668 FS(ph)PGAPGGSGSQPNQK ddPTM_HeLa_Curcumin_4h_R1 4 FSPGAPGGSGSQPNQK 16 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 0 FS(1)PGAPGGSGSQPNQK;FS(1)PGAPGGSGSQPNQK;FS(0.641)PGAPGGS(0.344)GS(0.015)QPNQK;FS(1)PGAPGGSGSQPNQK ;;; 270.51 3.53E-52 216019000 17046.2 15346.8 16555.6 16505.8 18940.1 15594.5 10191.3 5629.2 14378.7 11655.5 TRUE FALSE FALSE 15696.97528 16673.30901 17169.1651 16437.50337 18714.25168 12360.02491 10477.24045 7345.517166 12801.39258 12060.52776 1.301516451 1.38246927 1.423583233 1.36291742 1.551694259 1.02483284 0.868721557 0.609054373 1.061428889 1 13.55800542 -4.700812146 2.268492324 1.226332302 0.648349975 0.62144383 0.171344141 0.215514309 2.054411119 0.029818952 0.172492448 1.99E-05 4.700812146 -0.577982327 FS(ph)SKNQLK ddPTM_HeLa_Curcumin_4h_R1 1 FSSKNQLK 8 1 H7C5R8;Q460N5-5;Q460N5-3;Q460N5-4;Q460N5-1;Q460N5 H7C5R8 PARP14 Poly [ADP-ribose] polymerase 14 1 0 FS(0.5)S(0.5)KNQLK 107.29 0.0052834 5074700 1507.1 1281.7 1420.2 1471.2 1468.2 1576.8 1114.2 1121.5 1540.2 1293.2 TRUE FALSE FALSE 1387.811445 1392.484437 1472.833861 1465.112564 1450.692674 1249.753906 1145.461453 1463.440187 1371.243913 1338.138604 1.037120849 1.040613007 1.100658674 1.094888497 1.084112415 0.933949519 0.856011066 1.093638718 1.024739821 1 10.38601184 -5.247873725 24.8639166 1.035868332 0.950680891 0.274131213 0.064126734 777.0387885 1424199.14 0.009079728 0.023009832 5.65E-06 5.247873725 -0.08518744 FS(ph)SPHLLEALK ddPTM_HeLa_Curcumin_4h_R1 1 FSSPHLLEALK 11 0 Q96H22-5;Q96H22-4;Q96H22;Q96H22-3 Q96H22-5 CENPN Centromere protein N 1 0 FS(0.5)S(0.5)PHLLEALK 101.64 0.010087 10619000 1662.1 1715 1658.1 1880.4 1940.4 1550.2 1855.5 1363.7 2097.5 1685 TRUE FALSE FALSE 1530.543031 1863.236958 1719.550645 1872.619403 1917.261997 1228.671046 1907.560336 1779.485852 1867.409498 1743.553625 0.877829629 1.068643334 0.9862333 1.074024553 1.099628925 0.70469358 1.094064621 1.020608616 1.071036458 1 10.76781502 -7.261568172 24.99992631 0.942308438 1.003935989 0 0.118563855 27.86346354 5408606.578 0.018967564 0.022441961 5.48E-08 7.261568172 0.061627551 FS(ph)SPIVK ddPTM_HeLa_Curcumin_4h_R1 1 FSSPIVK 7 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 0 FS(0.5)S(0.5)PIVK 101.25 0.018973 123150000 9575.9 7565.6 8696.8 8890.2 8645.4 12704 8979.4 7331.1 10411 6974.1 TRUE FALSE FALSE 8817.957411 8219.536752 9019.111058 8853.414708 8542.309251 10069.0472 9231.337797 9566.318642 9268.939347 7216.449456 1.221924641 1.139000114 1.249798965 1.22683804 1.183727442 1.39529103 1.279207712 1.325626778 1.284418245 1 12.81707348 -13.52287875 0.109172692 0.120342003 1.424004306 0.01252598 0.102132811 32.62195425 0.261988269 6.407416329 0.338369579 3.00E-14 13.52287875 1.303662303 FS(ph)SPTEELDYR ddPTM_HeLa_Curcumin_4h_R1 1 FSSPTEELDYR 11 0 H0Y911;Q4VXL4;D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-2;O95359-6;O95359-1;O95359-5;O95359-3;O95359;E9PGB3 H0Y911 TACC2 Transforming acidic coiled-coil-containing protein 2 1 0 FS(0.5)S(0.5)PTEELDYR 213.63 7.20E-11 51772000 5929.5 5101.5 5249.1 6447.5 5946 3335.8 4064.8 8403.1 6783.2 4965.8 TRUE FALSE FALSE 5460.173818 5542.450928 5443.636264 6420.821953 5875.097833 2643.917478 4178.847348 10965.16651 6039.099931 5138.36118 1.062629431 1.078641756 1.059410982 1.249585564 1.143379694 0.514544888 0.813264619 2.133981268 1.175296893 1 12.32709259 -4.255192248 24.96406194 1.012489583 2.133981775 0.741064239 0.199183399 265.3807482 1060454.001 0.027087409 0.337899233 5.56E-05 4.255192248 1.121492192 FSAS(ph)SGGGGSR ddPTM_HeLa_Curcumin_4h_R1 2 FSASSGGGGSR 11 0 H0Y3P2;D3DQV9;P78344-2;P78344;H0YCH5;H0YEC5;H0YD77;H0YD99;H0YEN8;H0YDC0;H0YCF8 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 0 FS(0.001)AS(0.636)S(0.363)GGGGSR;FSAS(0.5)S(0.5)GGGGSR ; 196.67 1.59E-05 82089000 6139.1 5114.7 5488.9 6164.7 6326.7 8211.4 9153.9 6390.8 6270.8 5500.5 TRUE FALSE FALSE 5653.183757 5556.791877 5692.323463 6139.192105 6251.258235 6508.263078 9410.733798 8339.3255 5582.908929 5691.641966 0.993243038 0.976307349 1.000119736 1.078632869 1.098322465 1.143477246 1.65343039 1.465187999 0.980896016 1 12.4746292 -4.888974492 3.726509326 1.010152145 1.559839927 0.923365792 0.061133167 0.039151055 1.022904379 0.008719228 0.029634702 1.29E-05 4.888974492 0.549687782 FSASS(ph)GGGGSR ddPTM_HeLa_Curcumin_4h_R1 1 FSASSGGGGSR 11 0 H0Y3P2;D3DQV9;P78344-2;P78344;H0YCH5;H0YEC5;H0YD77;H0YD99;H0YEN8;H0YDC0;H0YCF8 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 0 FSAS(0.126)S(0.874)GGGGSR 196.67 1.59E-05 147630000 2690.3 1816.4 2166.5 2691.4 2662.2 3455.4 4093.1 2778.8 2673 2767.4 TRUE FALSE FALSE 2477.359916 1973.401522 2246.792396 2680.2637 2630.455004 2738.71109 4207.94137 3626.043328 2379.778588 2863.566944 0.865130784 0.689141047 0.78461319 0.935987792 0.918593857 0.956398486 1.469475466 1.266268049 0.831053939 1 11.48359762 -4.817417329 6.376025666 0.90511274 1.366932231 0.792494736 0.100387828 0.066540823 5.565651978 0.015616342 0.048597232 1.52E-05 4.817417329 0.461819491 FSCPPNFTAKPPAS(ph)ESPR ddPTM_HeLa_Curcumin_4h_R1 1 FSCPPNFTAKPPASESPR 18 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 0 FSCPPNFTAKPPAS(0.5)ES(0.5)PR 128.8 9.33E-05 51795000 1025 781.28 860.19 1120.8 1084.8 1261.6 893.11 925.73 1019.5 853.87 TRUE FALSE FALSE 943.8701684 848.8103619 892.0693981 1116.162427 1071.864469 999.9299388 918.1682629 1207.980815 907.6634007 883.5419189 1.068280008 0.960690538 1.009651471 1.263281801 1.213145008 1.131728917 1.03919038 1.367202608 1.027300891 1 9.787154774 -6.274236171 24.61483855 1.025017193 1.190428358 0.557444808 0.08382609 394.2046676 758257.924 0.012543475 0.019241236 5.32E-07 6.274236171 0.165411165 FSCPPNFTAKPPASES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 FSCPPNFTAKPPASESPR 18 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 0 FSCPPNFTAKPPAS(0.069)ES(0.931)PR 98.135 0.00075358 53217000 1537.6 1190.7 1114.5 1327.7 1495 1926.5 1276 969.13 1362.6 1408.1 TRUE FALSE FALSE 1415.897338 1293.618802 1155.80435 1322.206329 1477.173101 1526.922184 1311.801126 1264.613276 1213.126189 1457.03137 0.971768602 0.887845539 0.793259757 0.907465931 1.013823814 1.047967954 0.900324559 0.867938262 0.832601284 1 10.50881622 -7.442628082 4.726575569 0.987970983 0.920062863 0 0.083587158 0.321263898 12.36993407 0.012959406 0.014581265 3.61E-08 7.442628082 -0.06790812 FSEGVLQS(ph)PSQDQEK ddPTM_HeLa_Curcumin_4h_R1 4 FSEGVLQSPSQDQEK 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 FSEGVLQS(0.989)PS(0.011)QDQEK;FS(0.036)EGVLQS(0.947)PS(0.017)QDQEK;FSEGVLQS(0.989)PS(0.011)QDQEK;FSEGVLQS(1)PSQDQEK ;;; 203.52 2.05E-09 112087000 16741 12618.2 14146.8 14248.6 13425.3 21613.9 15569.1 7071.4 16195.2 13471 TRUE FALSE FALSE 15415.93218 13708.86098 14671.09285 14189.64307 13265.21207 17130.9335 16005.92704 9227.437307 14418.62708 13939.11625 1.105947602 0.983481358 1.052512411 1.017972934 0.951653737 1.228982756 1.148274163 0.661981516 1.034400375 1 13.76685148 -4.252953386 24.81924346 1.054838202 0.661981298 0.694128725 0.078865083 442.2506963 1293432.386 0.011263843 0.172349892 5.59E-05 4.252953386 -0.392856905 FSELTAEK ddPTM_HeLa_Curcumin_4h_R1 1 FSELTAEK 8 0 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 0 160.11 4.23E-06 4892400 3227 2192.9 2986.3 2854.5 2523.6 3078.9 2433.3 2504.2 3029.7 3389.8 FALSE FALSE TRUE 2971.579545 2382.444505 3096.974905 2842.688835 2493.507718 2440.301434 2501.571849 3267.719052 2697.34949 3507.595298 0.847184265 0.679224455 0.882933931 0.810438091 0.710888089 0.695719211 0.713187137 0.931612337 0.769002482 1 11.77626659 -8.378618008 0.562991593 1.002994672 0.764169908 0 0.106539957 0.46497317 0.315138328 0.05053168 0.022591369 4.18E-09 8.378618008 -0.238824764 FSFSPEPTLEDIRR ddPTM_HeLa_Curcumin_4h_R1 1 FSFSPEPTLEDIRR 14 1 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 0 0 96.23 0.010192 12119000 1989.2 1512.3 1715 1739.7 1579.1 1557.9 1144.8 1166 1961.6 1691.2 FALSE FALSE TRUE 1831.752721 1643.016473 1778.559409 1732.501582 1560.270264 1234.773979 1176.920007 1521.508032 1746.417388 1749.969074 1.046734338 0.938883148 1.016337623 0.9900184 0.891598764 0.7055976 0.672537603 0.869448526 0.997970429 1 10.77311371 -5.531712587 2.61788241 1.013714516 0.742149035 0.798533414 0.055546356 0.079118829 1.086547453 0.007969877 0.018719435 2.94E-06 5.531712587 -0.271565481 FSGDLDDQTCR ddPTM_HeLa_Curcumin_4h_R1 2 FSGDLDDQTCR 11 0 P05455 P05455 SSB Lupus La protein 0 0 ; ; 150.15 0.0013494 28418000 5805.5 4964.5 6171 5594.3 6617.6 6837.8 5322.7 5846.3 5013.1 5297.9 FALSE FALSE TRUE 5345.988549 5393.609259 6399.702689 5571.152269 6538.689442 5419.563202 5472.040637 7628.809957 4463.175472 5482.001631 0.975189157 0.983875895 1.167402551 1.016262425 1.192755837 0.988610286 0.998182964 1.391610304 0.814150701 1 12.42048704 -4.25979842 24.72227996 1.015726358 1.391610451 0.563176818 0.099461665 55.8700809 841633.5519 0.010860526 0.092744712 5.50E-05 4.25979842 0.375884093 FSGEEGEIEDDES(ph)GTENREEK ddPTM_HeLa_Curcumin_4h_R1 2 FSGEEGEIEDDESGTENREEK 21 1 Q9Y2W1 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 FSGEEGEIEDDES(0.793)GT(0.207)ENREEK;FSGEEGEIEDDES(0.829)GT(0.171)ENREEK ; 61.096 0.0045971 29951600 1982.88 2186.39 1909.42 1738.2 2534.3 2497.3 1850.07 1654.06 1853.62 2309 TRUE FALSE FALSE 1825.932956 2375.371809 1980.184785 1731.007789 2504.080128 1979.33183 1901.977985 2158.37528 1650.282524 2389.237578 0.764232478 0.994196572 0.828793588 0.724502161 1.048066609 0.828436589 0.796060636 0.903374072 0.690715121 1 11.2223346 -9.579845161 1.355241292 1.000230059 0.849614759 0 0.134588301 0.481299291 1.581115841 0.066140354 0.015335474 2.63E-10 9.579845161 -0.150615299 FSGEEGEIEDDES(ph)GTENREEKDNIQPTTE ddPTM_HeLa_Curcumin_4h_R1 2 FSGEEGEIEDDESGTENREEKDNIQPTTE 29 2 Q9Y2W1 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 FS(0.001)GEEGEIEDDES(0.492)GT(0.492)ENREEKDNIQPT(0.011)T(0.003)E;FSGEEGEIEDDES(0.5)GT(0.5)ENREEKDNIQPTTE ; 83.826 4.16E-06 16359200 2282.47 2231.3 2287.58 2566.6 3002.9 2639.9 2587.9 2216.1 2629.6 2227.3 TRUE FALSE FALSE 2101.810091 2424.16363 2372.359727 2555.980089 2967.092379 2092.354982 2660.509509 2891.778688 2341.139459 2304.698509 0.91196748 1.051835466 1.029357948 1.109030131 1.287410204 0.907864944 1.154385052 1.254731878 1.015811591 1 11.17036232 -6.608867171 1.568815261 0.960334611 1.138220451 0.324301113 0.101032659 0.286254133 1.422721414 0.016877068 0.0264402 2.46E-07 6.608867171 0.17788584 FSGFSAKPNNSGEAPS(ph)SPTPK ddPTM_HeLa_Curcumin_4h_R1 2 FSGFSAKPNNSGEAPSSPTPK 21 1 K7ENR9;K7ERZ5;P49916-4;P49916-3;P49916-2;P49916 K7ENR9 LIG3 DNA ligase 3 1 0 FSGFSAKPNNSGEAPS(0.838)S(0.132)PT(0.03)PK;FSGFSAKPNNS(0.008)GEAPS(0.484)S(0.484)PT(0.024)PK ; 112.58 1.14E-05 114542000 5001.3 4059.1 4758.6 4928.8 4904.1 5412 4560.8 2985.75 4943.6 4077.3 TRUE FALSE FALSE 4605.441828 4409.950517 4934.957902 4908.405932 4845.62181 4289.490194 4688.763773 3896.09143 4401.299448 4218.985872 1.091599253 1.045263163 1.169702401 1.163408952 1.148527622 1.016711201 1.111348536 0.923466337 1.043212654 1 12.04268054 -3.207971004 13.8863976 1.063109878 1.085348635 0 0.076293572 0 0 0.010525104 0 0.000619482 3.207971004 0.022238756 FSGWYDADLS(ph)PAGHEEAK ddPTM_HeLa_Curcumin_4h_R1 1 FSGWYDADLSPAGHEEAK 18 0 P18669 P18669 PGAM1 Phosphoglycerate mutase 1 1 0 FSGWYDADLS(1)PAGHEEAK 114.76 0.00023456 8467700 2483.3 2371 2518.1 2691.9 2421.2 3643.5 2159.1 1905.7 3273.9 2290.3 TRUE FALSE FALSE 2286.744185 2575.938675 2611.423001 2680.761631 2392.328771 2887.797029 2219.678535 2486.739157 2914.761361 2369.887755 0.964916663 1.086945434 1.101918433 1.131176625 1.009469232 1.21853747 0.936617581 1.049306725 1.229915364 1 11.21060301 -7.258253874 24.79755491 0.983432868 1.076908996 0 0.104924941 232.6166926 1810803.147 0.011138932 0.013332924 5.52E-08 7.258253874 0.093476128 FSK(ac)SATSPEGK ddPTM_HeLa_Curcumin_4h_R1 2 FSKSATSPEGK 11 1 P13639 P13639 EEF2 Elongation factor 2 0 1 ; FSK(1)SATSPEGK;FSK(1)SATSPEGK 116.74 0.0024849 6997800 4592.8 3889.6 4031.8 4028.5 3927.1 4904.6 3936.1 3751.7 4440.6 3865.7 FALSE TRUE FALSE 4229.275034 4225.799692 4181.222055 4011.831134 3880.271897 3887.330674 4046.536373 4895.576059 3953.47729 4000.032787 1.057310092 1.056441264 1.045296946 1.002949563 0.970060023 0.971824703 1.011625801 1.223883983 0.988361221 1 11.96579611 -4.259849498 24.91892793 1.020879149 1.223884053 0.797938164 0.031745045 52.06982501 816032.9078 0.005047342 0.043050962 5.50E-05 4.259849498 0.203004904 FSMPGFK ddPTM_HeLa_Curcumin_4h_R1 2 FSMPGFK 7 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 114.19 0.011148 14287000 12388.7 10404.4 12801.8 10775.7 13082.6 13763 11952.1 12084.5 11655.1 9354 FALSE FALSE TRUE 11408.12132 11303.70997 13276.24597 10731.11301 12926.59854 10908.39866 12287.44376 15769.00842 10376.56469 9679.050804 1.178640505 1.16785315 1.371647514 1.10869477 1.335523369 1.1270112 1.269488507 1.62918955 1.072064286 1 13.24064986 -1 0.096418092 0.850296307 2.452162922 0.504074574 0.122302737 77.29317289 0.534607019 1.089849889 16.44571105 0.1 1 1.601866615 FSNS(ph)MESLSSR ddPTM_HeLa_Curcumin_4h_R1 1 FSNSMESLSSR 11 0 Q9H792 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 0 FS(0.005)NS(0.974)MES(0.019)LS(0.002)SR 146.84 0.00087056 14616000 1419.7 877.95 1178.8 1149.3 1312.4 1307.8 1167.4 499.86 1374.3 1229.8 TRUE FALSE FALSE 1307.329247 953.8360859 1222.487365 1144.544501 1296.750487 1036.547538 1200.154102 652.2650129 1223.542728 1272.535458 1.027342097 0.749555605 0.960670571 0.899420518 1.019028962 0.814552971 0.943120362 0.512571189 0.96149991 1 10.31349014 -3.933238995 1.362228791 0.976441064 2.85E-35 0.604662456 0.095040959 1.33156746 1.19770267 0.014181889 2.216339521 0.000116617 3.933238995 -0.976441064 FSPDGELYASGSEDGTLR ddPTM_HeLa_Curcumin_4h_R1 2 FSPDGELYASGSEDGTLR 18 0 Q9Y3F4-2;Q9Y3F4;H0YH33 Q9Y3F4-2 STRAP Serine-threonine kinase receptor-associated protein 0 0 ; ; 151.3 0.00066019 7493100 2279 2147.45 2333.5 2429.1 2739.2 2928.6 2160.48 2236.6 2506.9 2090.29 FALSE FALSE TRUE 2098.614745 2333.066009 2419.981563 2419.049028 2706.536829 2321.175348 2221.097254 2918.529044 2231.899342 2162.927422 0.970265911 1.078661256 1.118845477 1.118414332 1.251330397 1.073163771 1.026894029 1.349342107 1.031888227 1 11.07876954 -6.936264805 1.849158917 0.985510658 1.153601001 0.392510067 0.086694584 0.219375352 1.503324366 0.014101073 0.018966493 1.16E-07 6.936264805 0.168090342 FSPGAPGGSGSQPNQK ddPTM_HeLa_Curcumin_4h_R1 2 FSPGAPGGSGSQPNQK 16 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 0 0 ; ; 223.36 6.84E-27 3780700 1650.67 1432.82 1854.44 2007.33 1460.02 2545.6 1703.49 1781.43 2162.93 1634.67 FALSE FALSE TRUE 1520.017728 1556.666576 1923.167178 1999.0242 1442.610215 2017.613865 1751.285345 2324.579806 1925.66199 1691.474661 0.898634643 0.920301446 1.136976641 1.181823321 0.852871313 1.192813532 1.035360083 1.37429183 1.138451574 1 10.72406585 -1 0.4564119 0.961321519 9.448829293 0.316929069 0.126501229 50.42846958 0.536849827 0.023878605 403.7714944 0.1 1 8.487507773 FSPPS(ph)PLPQAVFSTSSR ddPTM_HeLa_Curcumin_4h_R1 2 FSPPSPLPQAVFSTSSR 17 0 A0A1X7SBS4;Q99594 A0A1X7SBS4 TEAD3 Transcriptional enhancer factor TEF-5 1 0 FS(0.006)PPS(0.994)PLPQAVFSTSSR;FS(0.014)PPS(0.986)PLPQAVFSTSSR ; 166.36 0.00010082 48084000 2155.04 1459.49 1646.08 1892.17 1847.45 2193.72 1798.42 2289.87 1987.35 1829.49 TRUE FALSE FALSE 1984.46631 1585.641812 1707.085173 1884.340702 1825.420365 1738.717744 1848.878825 2988.040822 1769.342677 1893.064641 1.048282381 0.837605741 0.901757465 0.995391632 0.964267318 0.918467181 0.976659109 1.578414575 0.934644617 1 10.88650796 -4.260781279 24.9361809 0.987816954 1.578414762 0.890030135 0.064920944 14.14840312 535977.6963 0.01012004 0.081088466 5.49E-05 4.260781279 0.590597808 FSPVTPK(ac)FTPVASK ddPTM_HeLa_Curcumin_4h_R1 2 FSPVTPKFTPVASK 14 1 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 0 1 ; FSPVTPK(1)FTPVASK;FSPVTPK(1)FTPVASK 152.74 1.90E-17 0 400.28 408.4 381.09 67.838 122.815 451.41 386.6 479.68 394.82 190.61 FALSE TRUE FALSE 368.5974156 443.7002762 395.2135306 67.55730433 121.3505113 357.7824776 397.4469555 625.9322238 351.5092338 197.2336833 1.86883604 2.249617148 2.003783147 0.342524173 0.615262613 1.814002921 2.015106897 3.17355643 1.782196772 1 7.623762144 -9.298707102 1.040802411 1.002581995 1.716003749 0 0.792009606 1.028302116 2.007142531 0.531521525 0.14462428 5.03E-10 9.298707102 0.713421754 FSQMLQDK(ac)PLR ddPTM_HeLa_Curcumin_4h_R1 1 FSQMLQDKPLR 11 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 0 1 FSQMLQDK(1)PLR 79.659 0.018323 0 482.26 294.28 371.16 242.32 661.36 432.61 338.67 428.31 498.25 289.96 FALSE TRUE FALSE 444.0886121 319.7162519 384.9155161 241.317344 653.4737139 342.8818095 348.1721687 558.8997473 443.5932216 300.0360884 1.480117323 1.065592655 1.282897395 0.804294394 2.177983713 1.142801892 1.160434302 1.862775076 1.47846622 1 8.228992229 -11.91369267 0.286363462 7.80E-13 1.410262239 0 0.402922574 31.57337747 0.963036543 18.58301684 0.173414759 1.22E-12 11.91369267 1.410262239 FSQT(ph)LQRS(ph)IS(ph)FR ddPTM_HeLa_Curcumin_4h_R1 1 FSQTLQRSISFR 12 1 C9J609;C9JNF2;H7C4P0;C9J586;E7EU49;E9PG37;Q9NR81;Q9NR81-3;Q9NR81-2 C9J609 ARHGEF3 Rho guanine nucleotide exchange factor 3 3 0 FS(0.148)QT(0.852)LQRS(1)IS(1)FR 80.411 0.020017 2745600 2884.9 2481.3 2714.8 2761.6 2674.4 3238.9 2312.6 1278.3 2848.6 2562.8 TRUE FALSE FALSE 2656.557121 2695.772516 2815.412876 2750.173231 2642.509527 2567.11563 2377.485332 1668.047785 2536.115707 2651.857109 1.001772347 1.016560246 1.061675935 1.037074442 0.996475081 0.968044478 0.896535987 0.629011186 0.956354586 1 11.37278733 -4.026662636 1.345478464 1.009176306 0.276327089 0.94903538 0.026489161 0.294683243 0.308298419 0.003467203 0.340807763 9.40E-05 4.026662636 -0.732849217 FSS(ph)KNQLK ddPTM_HeLa_Curcumin_4h_R1 1 FSSKNQLK 8 1 H7C5R8;Q460N5-5;Q460N5-3;Q460N5-4;Q460N5-1;Q460N5 H7C5R8 PARP14 Poly [ADP-ribose] polymerase 14 1 0 FS(0.046)S(0.954)KNQLK 111.01 0.0048092 3997800 2625.2 2524.9 2188.1 2510.5 2892.6 3143.2 2020 1063.6 2900.7 3061.9 TRUE FALSE FALSE 2417.41265 2743.141105 2269.192911 2500.112216 2858.107634 2491.264889 2076.675763 1387.886744 2582.500467 3168.300797 0.762999729 0.865808293 0.716217637 0.789101912 0.902094787 0.78630946 0.655454105 0.43805397 0.815105835 1 11.6294936 -3.234150712 0.087593701 1.181194051 3.38E-25 0.444182662 0.107611783 57.36046956 0.603821884 1.750713841 8.742199996 0.000583243 3.234150712 -1.181194051 FSS(ph)PIVK ddPTM_HeLa_Curcumin_4h_R1 1 FSSPIVK 7 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 0 FS(0.071)S(0.929)PIVK 112.41 0.015343 119130000 6523.4 4947.6 5303.4 5571.2 5864.7 8128.5 6664.8 4912.8 6936.2 4549.4 TRUE FALSE FALSE 6007.066007 5375.248498 5499.948669 5548.147851 5794.767283 6442.557473 6851.796351 6410.690104 6175.316214 4707.491311 1.276065235 1.141849903 1.168339633 1.178578458 1.230967175 1.368575542 1.455509081 1.361806041 1.311806184 1 12.20074272 -1 0.031286221 1.02E-11 3.101173352 0.239166041 0.110201103 502.8521128 1.217865286 38.03066178 94.79919685 0.1 1 3.101173352 STS(ph)FGVPNANSIK ddPTM_HeLa_Curcumin_4h_R1 2 STSFGVPNANSIK 13 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6;H7BZZ8;B5MCI0;P53814-2;A0A096LNK9 A0A087WVP4 SMTN Smoothelin 1 0 STS(1)FGVPNANSIK;S(0.045)T(0.045)S(0.91)FGVPNANSIK ; 187.74 2.21E-05 59044000 5035.8 3807.3 4556.3 5086.4 5064.2 5248.4 4775.7 8072.8 4550 4743.1 TRUE FALSE FALSE 4637.211116 4136.386047 4725.160486 5065.353825 5003.812723 4159.822678 4909.693289 10534.15956 4050.876384 4907.922372 0.944841985 0.842797773 0.962761863 1.032077005 1.01953787 0.847573039 1.000360828 2.146358226 0.825374991 1 12.26089671 -4.262008783 5.907786629 0.962600202 2.179828458 0.958651926 0.074982535 0.015143888 2.432052883 0.008586098 0.073833424 5.47E-05 4.262008783 1.217228255 up FSS(ph)SGGGGGGGRFSSSSGYGGGSSR ddPTM_HeLa_Curcumin_4h_R1 1 FSSSGGGGGGGRFSSSSGYGGGSSR 25 1 P35527 P35527 KRT9 "Keratin, type I cytoskeletal 9" 1 0 FS(0.004)S(0.834)S(0.162)GGGGGGGRFSSSSGYGGGSSR 89.483 0.00032878 44369000 2264 1877.4 1451.4 1928.3 1963.7 2364.2 1522.2 1219.8 2255.9 2133.3 TRUE FALSE FALSE 2084.802011 2039.67409 1505.190161 1920.321206 1940.28416 1873.83827 1564.908835 1591.711405 2008.433414 2207.432016 0.944446758 0.924003129 0.681873847 0.869934472 0.878977992 0.848877001 0.708927307 0.721069276 0.909850632 1 11.10815329 -1.65678949 0.121646097 1.089209094 0.016949992 0.460878097 0.075771411 36.51955143 0.356179703 0.324618566 6.544454307 0.022039945 1.65678949 -1.072259102 FSSSIENSDS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 1 FSSSIENSDSPVR 13 0 O95425-3;A0A6I8PIX7;O95425-2;O95425;O95425-4 O95425-3 SVIL Supervillin 1 0 FSSSIENS(0.002)DS(0.998)PVR 109.55 0.0041446 90621000 4480.9 3671.6 4681.7 4342.7 4477.8 6439.4 6473.7 6464.9 5837.1 5278.9 TRUE FALSE FALSE 4126.232037 3988.956744 4855.20792 4324.731058 4424.40516 5103.795853 6655.334599 8436.018249 5196.784734 5462.341382 0.755396221 0.730265003 0.888851059 0.79173577 0.809983275 0.934360469 1.218403269 1.544396012 0.951384099 1 12.41530377 -4.501622411 1.837564481 0.858451645 1.608569748 0.884220119 0.080599019 0.165610209 0.800774906 0.015379966 0.180566523 3.15E-05 4.501622411 0.750118104 FSSSTEQSS(ph)ASR ddPTM_HeLa_Curcumin_4h_R1 2 FSSSTEQSSASR 12 0 A0A3B3ITC6;I3L0M7;I3L2W9;I3L2N2;Q92997-2;Q92997;O14641 A0A3B3ITC6 DVL2;DVL3 Segment polarity protein dishevelled homolog DVL-3;Segment polarity protein dishevelled homolog DVL-2 1 0 FSSSTEQS(0.004)S(0.995)AS(0.001)R;FSSSTEQS(0.086)S(0.914)ASR ; 120.59 0.0034289 7231400 4522.5 4166.9 4098.3 3693.2 4162 7203 6900.8 3016.3 4613.4 3647.8 TRUE FALSE FALSE 4164.539353 4527.068269 4250.186603 3677.918517 4112.370868 5709.016605 7094.417875 3935.955985 4107.321562 3774.560778 1.103317604 1.199362928 1.126008257 0.974396422 1.089496529 1.512498259 1.879534677 1.042758672 1.088158809 1 11.88209306 -5.268261577 6.223217174 1.063482155 1.520195374 0.448855408 0.198450795 0.082184564 15.44873126 0.025652704 0.061257418 5.39E-06 5.268261577 0.456713219 GSDALSET(ph)SSVSHIEDLEK ddPTM_HeLa_Curcumin_4h_R1 1 GSDALSETSSVSHIEDLEK 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 0 GS(0.001)DALS(0.369)ET(0.578)S(0.042)S(0.01)VS(0.001)HIEDLEK 104.23 0.00067308 17418000 3973.9 3095 2972.4 2567.1 4842 4106.4 1600.8 528.51 3227.9 2836.5 TRUE FALSE FALSE 3659.361622 3362.518009 3082.559759 2556.47802 4784.262312 3254.686351 1645.71414 689.650266 2873.807446 2935.068164 1.246772278 1.145635406 1.050251506 0.871011465 1.630034481 1.108896342 0.560707298 0.23496908 0.979128008 1 11.51917829 -4.637650936 3.18715006 1.13595641 0.286501358 0.702103114 0.195711372 0.09827771 1.882709269 0.027280399 0.134044482 2.30E-05 4.637650936 -0.849455053 down AS(ph)DPGLPAEEPKEK ddPTM_HeLa_Curcumin_4h_R1 2 ASDPGLPAEEPKEK 14 1 P27708;F8VPD4 P27708 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 0 AS(1)DPGLPAEEPKEK;AS(1)DPGLPAEEPKEK ; 186.29 0.00038234 203989000 13435.5 11799.4 13045.9 13303.6 13737.8 12832.8 7933.3 3867.3 13268.7 11093.3 TRUE FALSE FALSE 12372.066 12819.28756 13529.39253 13248.55323 13573.98571 10171.13262 8155.887047 5046.421967 11813.15681 11478.79135 1.077819574 1.116780258 1.178642604 1.154176675 1.182527436 0.886080452 0.710517928 0.439630081 1.029128978 1 13.48668312 -4.635408751 1.739730172 1.07133558 0.424941471 0.901409666 0.07127561 0.127870621 0.615324855 0.01228605 0.107482139 2.32E-05 4.635408751 -0.646394109 down FSTLTDDPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 FSTLTDDPSPR 11 0 Q14C86-4;Q14C86-5;Q14C86-2;Q14C86;Q14C86-6 Q14C86-4 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 0 FSTLT(0.022)DDPS(0.978)PR;FSTLT(0.001)DDPS(0.999)PR;FSTLTDDPS(1)PR;FSTLT(0.001)DDPS(0.999)PR ;;; 151.55 0.0005194 62017800 11154.4 10412.1 10530.1 11813 11403.2 16535.5 14413.1 9301.8 10947.6 9762.1 TRUE FALSE FALSE 10271.51747 11312.07553 10920.35477 11764.12094 11267.22429 13105.85091 14817.4928 12137.876 9746.67567 10101.33225 1.0168478 1.119859762 1.081080644 1.16461083 1.115419631 1.297437861 1.466885004 1.201611401 0.964890118 1 13.30225796 -5.686539883 0.623312818 1.005921599 1.375171497 0.710849015 0.077154328 0.368109066 0.232522389 0.014809661 0.070964817 2.06E-06 5.686539883 0.369249898 FSTPEQAAK ddPTM_HeLa_Curcumin_4h_R1 1 FSTPEQAAK 9 0 P14866;M0QXS5;A0A3B3ITJ4;P14866-2;M0QYT0 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 0 134.77 0.00034729 3778800 3586.7 2532.4 2546.6 3003.2 3114.2 3917.1 2868.4 2661.4 3199.1 2788.1 FALSE FALSE TRUE 3302.80891 2751.289372 2640.979236 2990.773554 3077.065199 3104.649305 2948.879584 3472.848608 2848.166734 2884.986267 1.144826562 0.953657701 0.91542177 1.036668212 1.066578803 1.076140064 1.022146836 1.203766079 0.987237536 1 11.49434874 -4.255372025 23.74690614 1.047786413 1.203766222 0.352857514 0.066094781 358.9412475 1404767.921 0.010695456 0.127462898 5.55E-05 4.255372025 0.15597981 FSTYSQS(ph)PPDTPSLR ddPTM_HeLa_Curcumin_4h_R1 3 FSTYSQSPPDTPSLR 15 0 H3BMG9;H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4 H3BMG9 FAM65A Protein FAM65A 1 0 FSTYS(0.001)QS(0.999)PPDTPSLR;FST(0.026)YS(0.088)QS(0.825)PPDT(0.059)PS(0.001)LR;FSTYS(0.001)QS(0.604)PPDT(0.382)PS(0.012)LR ;; 240.5 5.16E-29 161408000 4773.5 4634.6 4690.1 4427.4 5308.9 6448.9 4213 3175.67 5303.6 4622.4 TRUE FALSE FALSE 4395.672438 5035.194173 4863.919232 4409.080592 5245.594835 5111.325446 4331.205441 4143.917164 4721.808349 4783.028056 0.919014563 1.05272102 1.016912127 0.92181784 1.096710028 1.068637981 0.905536282 0.866379439 0.987200638 1 12.22370854 -4.541230773 23.27042242 0.984051653 0.876168592 0.368630038 0.058399497 86.05939136 109123.8448 0.009022378 0.03377701 2.88E-05 4.541230773 -0.107883061 FSTYTS(ph)DKDENKLSEASGGR ddPTM_HeLa_Curcumin_4h_R1 2 FSTYTSDKDENKLSEASGGR 20 2 Q8WU90 Q8WU90 ZC3H15 Zinc finger CCCH domain-containing protein 15 1 0 FS(0.028)T(0.024)Y(0.058)T(0.07)S(0.818)DKDENKLS(0.002)EASGGR;FS(0.005)T(0.017)Y(0.011)T(0.203)S(0.763)DKDENKLS(0.001)EASGGR ; 80.002 0.0019694 32381000 2960.95 3110.63 2528.96 3132.95 3154.33 3716.95 2845.21 2758.05 3489.19 3519.35 TRUE FALSE FALSE 2726.587683 3379.498997 2622.685482 3119.986683 3116.716675 2946.012671 2925.038935 3598.966748 3106.434587 3641.647151 0.748723742 0.928013851 0.720192093 0.856751507 0.855853559 0.808978067 0.803218657 0.988279918 0.853030087 1 11.83037543 -9.506752199 1.234916411 1.000717445 0.826878302 0.033929467 0.087016128 0.347467363 0.942100129 0.051303447 0.012188946 3.11E-10 9.506752199 -0.173839144 FSVCVLGDQQHCDEAK ddPTM_HeLa_Curcumin_4h_R1 1 FSVCVLGDQQHCDEAK 16 0 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 0 94.007 0.004284 0 1373.7 1101.3 1296.2 1312.7 1305.2 1433.8 986.15 891.45 1673 1237.3 FALSE FALSE TRUE 1264.970195 1196.491465 1344.238312 1307.268395 1289.636342 1136.413718 1013.818715 1163.249001 1489.476086 1280.296083 0.988029419 0.934542783 1.049943314 1.021067246 1.00729539 0.887617898 0.791862701 0.908578115 1.163384084 1 10.32226177 -5.15524077 4.023069612 0.996701627 0.848379186 0.540765174 0.065101365 0.081149992 2.296995107 0.005059604 0.013754846 6.99E-06 5.15524077 -0.148322441 FT(ph)DKDQQPS(ph)GSEGEDDDAEAALKK ddPTM_HeLa_Curcumin_4h_R1 1 FTDKDQQPSGSEGEDDDAEAALKK 24 2 H3BNW0;Q9NXG2 H3BNW0 THUMPD1 THUMP domain-containing protein 1 2 0 FT(0.837)DKDQQPS(0.962)GS(0.201)EGEDDDAEAALKK 45.659 0.013972 71848000 3700.6 3065.9 2959.5 3038.9 2971.5 3639.7 3078.1 2763.7 3247.5 2711.6 TRUE FALSE FALSE 3407.693605 3330.902735 3069.181673 3026.325837 2936.066803 2884.785192 3164.463202 3606.339407 2891.257375 2805.827898 1.214505568 1.187137221 1.093859561 1.078585696 1.046417282 1.028140462 1.127817998 1.28530314 1.030447155 1 11.45421081 -9.574412271 1.381305869 1.000607956 1.136785395 0.278123629 0.075198023 0.455884286 1.570574496 0.056802923 0.013553373 2.66E-10 9.574412271 0.136177438 FT(ph)GSFDDDPDPHRDPYGEEVDR ddPTM_HeLa_Curcumin_4h_R1 1 FTGSFDDDPDPHRDPYGEEVDR 22 1 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;X6RGP5;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 FT(0.605)GS(0.395)FDDDPDPHRDPYGEEVDR 91.481 0.00010218 4822800 1027.1 842.86 924.38 823.25 1021.8 1710.7 1682.3 730.62 839.97 1008.6 TRUE FALSE FALSE 945.8039512 915.7130627 958.638336 819.8436096 1009.615702 1355.881536 1729.50081 953.3826746 747.8273925 1043.648775 0.906247364 0.877414974 0.918544973 0.785555092 0.967390301 1.299174175 1.65716748 0.913509121 0.716550827 1 10.02742056 -5.264371089 5.11195155 0.932673647 1.330266571 0.478641669 0.189189514 0.100683073 8.556804752 0.022896531 0.055958387 5.44E-06 5.264371089 0.397592924 FT(ph)NKPYLTSHRRIHTGEK ddPTM_HeLa_Curcumin_4h_R1 1 FTNKPYLTSHRRIHTGEK 18 3 C9JZE3;C9JYJ8;Q9BWE0;Q9BWE0-4 C9JZE3 REPIN1 Replication initiator 1 1 0 FT(0.957)NKPY(0.004)LT(0.014)S(0.026)HRRIHTGEK 55.011 0.011482 663630000 3081.7 6381.7 5690.6 4581.5 3115.3 3826.9 4711.5 4091 6153.3 11248 TRUE FALSE FALSE 2837.780193 6933.305712 5901.498642 4562.542967 3078.152082 3033.157802 4843.69201 5338.327067 5478.298385 11638.86716 0.243819278 0.595702796 0.507050949 0.392009197 0.264471794 0.26060593 0.416165245 0.458663802 0.47069 1 13.50666302 -9.388001174 0.88171545 1.039108925 0.382043507 0.150112865 0.194168375 0.239982026 0.30065384 0.110732943 0.02246879 4.09E-10 9.388001174 -0.657065418 FT(ph)S(ph)SRMS(ph)S(ph)FNR ddPTM_HeLa_Curcumin_4h_R1 2 FTSSRMSSFNR 11 1 Q8NI51-11;Q8NI51-6 Q8NI51-11 4 0 FT(0.998)S(0.949)S(0.053)RMS(1)S(1)FNR;FT(0.997)S(0.956)S(0.047)RMS(1)S(1)FNR ; 80.17 0.004907 0 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 FT(ph)SPADLDASGAGPGPK ddPTM_HeLa_Curcumin_4h_R1 1 FTSPADLDASGAGPGPK 17 0 P52735-3;P52735-2;P52735 P52735-3 VAV2 Guanine nucleotide exchange factor VAV2 1 0 FT(0.562)S(0.438)PADLDAS(0.001)GAGPGPK 95.57 0.008749 5575700 1818.8 1742.7 1842.9 1694.1 2239.8 2445.3 1985.7 1557.2 1870.2 1712.6 TRUE FALSE FALSE 1674.840061 1893.331223 1911.199495 1687.090263 2213.091848 1938.117216 2041.413398 2031.983112 1665.043739 1772.112723 0.945109213 1.06840338 1.078486414 0.95202198 1.248843722 1.093676035 1.151965883 1.14664439 0.939581167 1 10.79125466 -6.204773026 0.876580026 0.976663611 1.154482596 0.523679747 0.06764692 0.321402628 0.486008206 0.01205638 0.028395248 6.24E-07 6.204773026 0.177818985 FT(ph)VYPIMPAAGPK ddPTM_HeLa_Curcumin_4h_R1 1 FTVYPIMPAAGPK 13 0 A0A3B3IRP6;A0A0J9YVP0;O95714 A0A3B3IRP6 HERC2 E3 ubiquitin-protein ligase HERC2 1 0 FT(1)VYPIMPAAGPK 92.247 0.0042821 0 1083 841.42 970.42 1085.9 858.22 1513.4 1196.1 1294.3 1318.8 915.63 TRUE FALSE FALSE 997.2794072 914.1485955 1006.384619 1081.406834 847.986287 1199.50378 1229.659347 1688.926112 1174.130939 947.4480743 1.052595318 0.964853505 1.062205567 1.141389025 0.895021384 1.266036433 1.297864633 1.782605461 1.239256241 1 9.887903067 -3.657600615 0.887932399 1.023044816 3.301987258 0.812368588 0.104182509 1.07821105 0.298942309 0.011120414 3.086780614 0.000219988 3.657600615 2.278942442 FTDEEVDELYR ddPTM_HeLa_Curcumin_4h_R1 5 FTDEEVDELYR 11 0 J3QRS3;P19105;O14950 J3QRS3 MYL12A;MYL12B Myosin regulatory light chain 12A;Myosin regulatory light chain 12B 0 0 ;;;; ;;;; 275.01 9.07E-55 1087931100 14317.4 12593.9 14671.1 14390.1 15122.3 17818.5 15651.8 15095.3 13846.7 11713 FALSE FALSE TRUE 13184.16268 13682.4606 15214.82387 14330.55758 14941.97645 14122.74224 16090.94738 19697.78748 12327.75165 12120.02588 1.087799879 1.128913481 1.255345824 1.182386715 1.232833708 1.165240271 1.327633088 1.62522652 1.017139054 1 13.56510516 -1 0.274788014 1.021595942 4.795591481 0.825776079 0.071544724 14.11117919 0.179417096 0.033455169 25.74477983 0.1 1 3.773995539 FTDEEVDEMYR ddPTM_HeLa_Curcumin_4h_R1 4 FTDEEVDEMYR 11 0 P24844;P24844-2 P24844 MYL9 Myosin regulatory light polypeptide 9 0 0 ;;; ;;; 250.75 8.14E-32 91728000 7527.4 7366.3 7943.5 7569.4 8390.1 9622.9 8053.9 7881.6 7193.3 6730.7 FALSE FALSE TRUE 6931.598347 8003.010148 8237.893098 7538.079828 8290.053537 7627.002068 8279.870758 10284.66356 6404.212987 6964.591324 0.995262755 1.14909975 1.182825052 1.082343454 1.190314428 1.095111215 1.188852349 1.476707402 0.919538949 1 12.76582298 -1 0.288040769 0.993635583 4.140831245 0.712978448 0.078236832 19.02836903 0.243091418 0.031307202 30.84875182 0.1 1 3.147195663 FTDFDEVRQEIEAETDR ddPTM_HeLa_Curcumin_4h_R1 2 FTDFDEVRQEIEAETDR 17 1 P50570-3;P50570-2;P50570-5;P50570-4;P50570 P50570-3 DNM2 Dynamin-2 0 0 ; ; 125.33 0.00036349 3522010 2732.2 2459.31 2116.44 2642.6 2641 2653.64 2234.8 2049.96 2229.95 2128.12 FALSE FALSE TRUE 2515.943487 2671.881798 2194.877128 2631.665621 2609.5078 2103.245151 2297.502473 2674.983367 1985.330064 2202.072012 1.14253461 1.213348966 0.996732676 1.195086086 1.185023826 0.955120968 1.043336667 1.214757443 0.901573633 1 11.10464593 -9.317380878 1.05839987 1.000435101 1.115596911 0.305755008 0.093531536 0.677079121 1.36608327 0.057290682 0.015445103 4.82E-10 9.317380878 0.11516181 FTDKDQQPS(ph)GS(ph)EGEDDDAEAALKK ddPTM_HeLa_Curcumin_4h_R1 3 FTDKDQQPSGSEGEDDDAEAALKK 24 2 H3BNW0;Q9NXG2 H3BNW0 THUMPD1 THUMP domain-containing protein 1 2 0 FT(0.024)DKDQQPS(0.981)GS(0.995)EGEDDDAEAALKK;FT(0.016)DKDQQPS(0.986)GS(0.998)EGEDDDAEAALKK;FTDKDQQPS(1)GS(1)EGEDDDAEAALKK ;; 115.85 4.85E-05 555750000 13135.8 11323.6 11709.8 11673.8 10953.8 13679.3 11592.8 10032.1 13020.7 11147.3 TRUE FALSE FALSE 12096.08757 12302.36153 12143.77549 11625.49691 10823.18309 10842.05898 11918.06277 13090.84111 11592.36179 11534.66785 1.048672379 1.066555335 1.052806691 1.007874441 0.938317707 0.939954156 1.033238488 1.134912707 1.005001786 1 13.49368884 -6.030466506 23.38312857 1.029596208 1.003665888 0.033415161 0.054935654 874.3118046 671036.4457 0.008732763 0.01449877 9.32E-07 6.030466506 -0.02593032 FTEYETQVK ddPTM_HeLa_Curcumin_4h_R1 1 FTEYETQVK 9 0 K7EJM5;A0A087WX29;A0A0A0N0M3;K7EN94;B1AKP7;G3V162;A0A087X260;A0A087WYY0;Q13148;A0A087WW61;A0A087WX67;A0A087WXV3;A0A087WXQ5;A0A087WV68;Q13148-4 K7EJM5 TARDBP;TDP43 TAR DNA-binding protein 43 0 0 105.52 0.0050835 2817300 776.94 913.74 701.24 625.16 1141.6 1069.6 1009.8 878.16 1069.6 709.97 FALSE FALSE TRUE 715.4443792 992.7196141 727.2285713 622.5732536 1127.987166 847.7529031 1038.13227 1145.906941 952.267556 734.6414047 0.973868849 1.351298209 0.989909589 0.847451899 1.535425527 1.153968314 1.413114295 1.559818075 1.29623453 1 9.520896399 -2.579133152 0.326485587 0.978732085 3.229691614 0.286869134 0.203334349 10.76908509 0.345462865 0.057486756 12.0986254 0.002635523 2.579133152 2.25095953 FTGS(ph)FDDDPDPHRDPYGEEVDR ddPTM_HeLa_Curcumin_4h_R1 1 FTGSFDDDPDPHRDPYGEEVDR 22 1 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;X6RGP5;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 FT(0.25)GS(0.75)FDDDPDPHRDPYGEEVDR 101.92 2.80E-05 4438100 513.73 714.49 797.42 505.1 725.66 1539.9 1574.3 640.49 469.11 639.65 TRUE FALSE FALSE 473.0677284 776.2473319 826.9730867 503.01003 717.0069784 1220.507382 1618.470621 835.7724525 417.6498067 661.8777899 0.714735765 1.172795558 1.249434713 0.759974179 1.083292096 1.844007157 2.445271084 1.262729261 0.631007435 1 9.37042105 -5.293864607 3.877307584 0.914352003 1.923359072 0.624046599 0.323077112 0.093494408 3.090255206 0.042841305 0.105736517 5.08E-06 5.293864607 1.009007069 FTGS(ph)FDDDPDPHRDPYGEEVDRR ddPTM_HeLa_Curcumin_4h_R1 1 FTGSFDDDPDPHRDPYGEEVDRR 23 2 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;X6RGP5;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 FT(0.217)GS(0.783)FDDDPDPHRDPYGEEVDRR 51.966 0.0056257 16457000 1479.2 1010.7 1415.9 1562.7 1535 3083.6 2315.2 1711.2 1859.5 1470.5 TRUE FALSE FALSE 1362.119759 1098.060404 1468.3745 1556.233961 1516.696128 2444.026601 2380.158281 2232.937003 1655.517502 1521.599766 0.895189254 0.721648642 0.965020193 1.022761699 0.996777314 1.606221725 1.564247271 1.467492999 1.088011144 1 10.57137321 -5.298350345 5.496406266 0.939635463 1.549092152 0.884837708 0.097543432 0.040619778 3.404493327 0.013469764 0.031338784 5.03E-06 5.298350345 0.609456689 FTGSFDDDPDPHRDPY(ph)GEEVDRR ddPTM_HeLa_Curcumin_4h_R1 1 FTGSFDDDPDPHRDPYGEEVDRR 23 2 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;X6RGP5;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 FT(0.133)GS(0.416)FDDDPDPHRDPY(0.451)GEEVDRR 44.054 0.018997 85955000 1148 963.89 1142.5 1066.3 1193.5 2297.1 2002.5 925.48 1173.1 1164.7 TRUE FALSE FALSE 1057.134589 1047.204357 1184.842055 1061.887933 1179.268292 1820.655566 2058.684761 1207.654592 1044.413865 1205.173238 0.877164008 0.868924337 0.983130074 0.881108126 0.978505209 1.510700295 1.708206501 1.002058918 0.866608909 1 10.23502483 -5.294124929 6.99844245 0.935140487 1.437228788 0.626778393 0.170791652 0.088209283 15.06863899 0.022307053 0.05098681 5.08E-06 5.294124929 0.502088301 FTGSFDDDPDPHRDPYGEEVDRR ddPTM_HeLa_Curcumin_4h_R1 1 FTGSFDDDPDPHRDPYGEEVDRR 23 2 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;X6RGP5;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 0 0 45.424 0.015079 35017000 4449.9 3574.6 3736.1 3637.9 3737.4 3851.3 1998.8 1238.2 4379.3 3551.7 FALSE FALSE TRUE 4097.685719 3883.572496 3874.563153 3622.847334 3692.833946 3052.496967 2054.880949 1615.72148 3898.901746 3675.121311 1.114979717 1.056719539 1.054268098 0.985776258 1.004819606 0.830584002 0.559132822 0.439637591 1.060890626 1 11.84357616 -4.804416192 1.303197673 1.053166319 0.380573453 0.978047021 0.032481967 0.0839668 0.217309282 0.006910272 0.057648348 1.57E-05 4.804416192 -0.672592866 down FTPPAESGSPS(ph)KETLPPPAAPPKPGK ddPTM_HeLa_Curcumin_4h_R1 2 FTPPAESGSPSKETLPPPAAPPKPGK 26 2 C9K0J5;Q70E73 C9K0J5 RAPH1 Ras-associated and pleckstrin homology domains-containing protein 1 1 0 FT(0.015)PPAES(0.072)GS(0.072)PS(0.421)KET(0.421)LPPPAAPPKPGK;FT(0.001)PPAES(0.138)GS(0.138)PS(0.559)KET(0.163)LPPPAAPPKPGK ; 84.166 2.05E-05 126478000 5320.6 4420.7 4670.5 5123.4 5112.4 6558 4902.5 2793.7 5879.3 4545.1 TRUE FALSE FALSE 4899.468896 4802.80561 4843.592839 5102.200728 5051.437969 5197.796876 5040.050956 3645.486269 5234.355499 4703.041887 1.041765949 1.021212595 1.029885116 1.084872483 1.074078881 1.105198933 1.07165768 0.775133702 1.112972333 1 12.19937847 -4.256831136 24.9861033 1.037129204 0.775133596 0.801478869 0.041144234 160.4388695 869875.2652 0.005678145 0.060793128 5.54E-05 4.256831136 -0.261995608 FTPVASKFS(ph)PGAPGGSGSQPNQK ddPTM_HeLa_Curcumin_4h_R1 1 FTPVASKFSPGAPGGSGSQPNQK 23 1 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 0 FTPVAS(0.002)KFS(0.997)PGAPGGSGSQPNQK 113.68 3.14E-06 648590000 4736.9 3245.2 3995.1 4029.5 3450.7 3695.8 1945.5 1380.8 4148.6 3429.1 TRUE FALSE FALSE 4361.969367 3525.700628 4143.16192 4012.826997 3409.552656 2929.24942 2000.085494 1801.799564 3693.508959 3548.26097 1.229325972 0.993641859 1.167659864 1.130927807 0.960908086 0.825545089 0.563680493 0.507797927 1.040934979 1 11.79289641 -4.998223317 1.350194859 1.107815551 0.475017201 0.897672799 0.073682768 0.136651623 0.424156812 0.014086575 0.081057707 1.00E-05 4.998223317 -0.63279835 YRSDS(ph)QDEVEK ddPTM_HeLa_Curcumin_4h_R1 1 YRSDSQDEVEK 11 1 H7C5V5;H0YF01;H0YBZ4;Q15390-2;Q15390 H7C5V5 MTFR1 Mitochondrial fission regulator 1 1 0 YRSDS(1)QDEVEK 128.73 0.0012541 0 1296.3 1097.7 1006.9 1313 1391.3 1401.8 670.03 310.61 1485 1069.7 TRUE FALSE FALSE 1193.696487 1192.580297 1044.2166 1307.567154 1374.709656 1111.050878 688.8292385 405.3135591 1322.099215 1106.871995 1.078441312 1.077432894 0.943394181 1.181317406 1.241977087 1.003775399 0.622320595 0.366179252 1.19444635 1 10.11227268 -4.634595309 2.68377424 1.05921499 0.390546592 0.872455731 0.093164913 0.069819741 0.939216713 0.012726929 0.071752558 2.32E-05 4.634595309 -0.668668397 down FTQAGSEVSALLGR ddPTM_HeLa_Curcumin_4h_R1 1 FTQAGSEVSALLGR 14 0 P06576;H0YH81;F8W0P7 P06576 ATP5B "ATP synthase subunit beta, mitochondrial;ATP synthase subunit beta" 0 0 130.15 1.40E-09 0 451.78 559.94 471.91 655.24 480.7 159.52 364.84 379.46 516.04 464.3 FALSE FALSE TRUE 416.0211363 608.3387186 489.3993997 652.5287905 474.9679665 126.4337538 375.0764285 495.1556072 459.4317031 480.4343904 0.865927054 1.266226421 1.018660216 1.358205831 0.988621914 0.263165494 0.780702706 1.030641472 0.956283963 1 8.908195615 -5.470017523 24.99815532 1.002953892 0.688001405 0.337099607 0.228737297 333.8087907 157858.2133 0.033378743 0.074636622 3.39E-06 5.470017523 -0.314952487 FTS(ph)PADLDASGAGPGPK ddPTM_HeLa_Curcumin_4h_R1 1 FTSPADLDASGAGPGPK 17 0 P52735-3;P52735-2;P52735 P52735-3 VAV2 Guanine nucleotide exchange factor VAV2 1 0 FT(0.101)S(0.899)PADLDASGAGPGPK 182.7 5.74E-06 12831000 2125.1 1811.5 2169.1 1966.4 2005.8 2506.3 1940.8 1684 1973.5 1820.6 TRUE FALSE FALSE 1956.896093 1968.077988 2249.488754 1958.263558 1981.882145 1986.465128 1995.253625 2197.443848 1757.011987 1883.865714 1.038766233 1.044701845 1.194081264 1.039492116 1.052029415 1.054462169 1.059127309 1.16645461 0.932663074 1 10.87948042 -7.349954139 1.944234959 1.01525887 1.086818305 0.375506089 0.056042157 0.303577054 2.179632548 0.009204955 0.010561918 4.47E-08 7.349954139 0.071559435 FVADGIFK ddPTM_HeLa_Curcumin_4h_R1 2 FVADGIFK 8 0 E9PL09;P23396;P23396-2;E9PPU1;E9PQ96;E9PJH4;F2Z2S8;E9PK82;H0YCJ7;E9PQX2 E9PL09 RPS3 40S ribosomal protein S3 0 0 ; ; 117.02 9.64E-05 2035000 6022 4222.3 5798.6 4984.6 5098.5 6032.5 5323.7 4894.7 5128.4 4345.6 FALSE FALSE TRUE 5545.352346 4587.256798 6013.501217 4963.975046 5037.703717 4781.2915 5473.068694 6387.071498 4565.827351 4496.609277 1.233229753 1.020159083 1.337341283 1.103937376 1.12033388 1.06331042 1.217154606 1.420419499 1.015393393 1 12.13462181 -9.428038379 0.894438357 0.986941759 1.185351095 0.280835387 0.116139751 0.762232522 0.968759959 0.108462737 0.02099232 3.73E-10 9.428038379 0.198409336 FVEK(ac)MTIFVK ddPTM_HeLa_Curcumin_4h_R1 1 FVEKMTIFVK 10 1 H9KV28 H9KV28 DIAPH1 0 1 FVEK(1)MTIFVK 45.368 0.017162 3925800 3797.5 3532 4008.4 3946.4 4014.4 4868 3071.8 4305.5 3491.7 2949.7 FALSE TRUE FALSE 3496.923868 3837.290342 4156.95483 3930.070842 3966.530902 3858.321926 3157.986441 5618.22713 3108.669246 3052.201855 1.145705308 1.257220369 1.361952789 1.28761826 1.299563754 1.264110996 1.03465845 1.840712835 1.018500543 1 11.57563466 -1.000000002 0.080121926 0.713063029 2.676632867 0.405693696 0.178966222 132.8580279 0.783031987 2.965034595 29.03916326 0.099999999 1.000000002 1.963569837 FVEWLK ddPTM_HeLa_Curcumin_4h_R1 1 FVEWLK 6 0 Q7L1Q6-2;Q7L1Q6;Q7L1Q6-4;Q7L1Q6-3;H0Y503 Q7L1Q6-2 BZW1 Basic leucine zipper and W2 domain-containing protein 1 0 0 102.98 0.014545 0 296.04 407.06 187.9 360.02 359.92 412.7 209.47 57.514 314.17 300.1 FALSE FALSE TRUE 272.6081216 442.2444526 194.8637393 358.5303326 355.6281891 327.1013679 215.3471644 75.04975384 279.706337 310.5284527 0.87788452 1.42416725 0.627522978 1.154581262 1.14523544 1.053370038 0.693486096 0.241683985 0.900743022 1 8.278581654 -4.403369447 2.567126183 0.988289852 0.19096503 0.591128203 0.200436702 0.192011668 1.92821992 0.026321524 0.284063878 3.95E-05 4.403369447 -0.797324822 FVEWLQNAEEES(ph)ESEGEEN ddPTM_HeLa_Curcumin_4h_R1 1 FVEWLQNAEEESESEGEEN 19 0 E9PFD4;B5MCE7;B5MCH7;Q9Y6E2 E9PFD4 BZW2 Basic leucine zipper and W2 domain-containing protein 2 1 0 FVEWLQNAEEES(0.897)ES(0.103)EGEEN 123.08 0.00019172 1129300 1264.9 915.66 962.34 1017.5 1038.7 979.08 945.71 778.27 1112.1 1083.6 TRUE FALSE FALSE 1164.78183 994.8055703 998.005167 1013.289855 1026.314181 776.0077715 972.2440774 1015.56094 990.1054123 1121.255019 1.038819724 0.887225076 0.890078662 0.903710429 0.915326276 0.69208856 0.867103434 0.905735914 0.883033204 1 10.13089873 -7.172610979 4.07284718 1.018388548 0.861119899 0.253738007 0.074504422 0.122875271 3.737757357 0.010564345 0.012964198 6.72E-08 7.172610979 -0.157268648 FVFSLVDAMNGK ddPTM_HeLa_Curcumin_4h_R1 1 FVFSLVDAMNGK 12 0 P40926;P40926-2;G3XAL0 P40926 MDH2 "Malate dehydrogenase, mitochondrial;Malate dehydrogenase" 0 0 101.66 0.012152 349520 80.935 0 0 167.94 150.98 0 0 132 0 0 FALSE FALSE TRUE 74.52890935 0 0 167.2451088 149.1796621 0 0 172.2461923 0 0 0 FVGQSEGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 FVGQSEGKK 9 1 Q9NWH9;Q9NWH9-3;H7C3F4;H0YMM0 Q9NWH9 SLTM SAFB-like transcription modulator 0 1 ; FVGQSEGK(1)K;FVGQSEGK(1)K 126.24 0.00029555 8935600 5448 4971 5875.4 4934 4904.3 7157.6 5234.1 5330.1 5327.6 5262 FALSE TRUE FALSE 5016.785051 5400.67109 6093.147493 4913.584415 4845.819426 5673.033077 5380.954759 6955.222953 4743.175609 5444.854108 0.921380987 0.991885362 1.119065336 0.902427194 0.8899815 1.04190727 0.988264268 1.277393813 0.871129972 1 12.41067768 -3.953423864 1.79551233 0.969349933 1.654963809 0.618434019 0.072431752 1.157302133 1.828024074 0.009532603 1.756170707 0.000111321 3.953423864 0.685613876 SAT(ph)TTGSPGTEK ddPTM_HeLa_Curcumin_4h_R1 1 SATTTGSPGTEK 12 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 0 S(0.026)AT(0.456)T(0.456)T(0.059)GS(0.002)PGTEK 234.63 5.77E-19 10041000 4374.2 4947.6 4895.1 3904 3816.4 3640 2505.6 864.51 3793.5 5210.5 TRUE FALSE FALSE 4027.977454 5375.248498 5076.516712 3887.846282 3770.891923 2885.022969 2575.900393 1128.095119 3377.362541 5391.564487 0.747088802 0.996973793 0.941566539 0.721097984 0.699405883 0.535099409 0.477764923 0.209233354 0.626416052 1 12.39648825 -4.634028564 0.606257227 0.898978865 9.13E-22 0.747754495 0.11904817 0.745763598 0.243459959 0.020241653 0.426334036 2.32E-05 4.634028564 -0.898978865 down FVIATSTK ddPTM_HeLa_Curcumin_4h_R1 2 FVIATSTK 8 0 Q02878 Q02878 RPL6 60S ribosomal protein L6 0 0 ; ; 113.5 0.0045584 5744400 10348.7 7293.9 9270.1 8396 9525 11143.6 8659.3 8696.2 9182 8346.8 FALSE FALSE TRUE 9529.589475 7924.352215 9613.658061 8361.259577 9411.420596 8832.291746 8902.256653 11347.63135 8174.757572 8636.850679 1.103363926 0.91750483 1.113097635 0.968091251 1.089681985 1.022628742 1.030729485 1.313862167 0.9464975 1 13.07628963 -4.26026046 24.79740228 1.039945946 1.313862265 0.633731217 0.065356506 40.73693058 856739.5694 0.007953786 0.06557071 5.49E-05 4.26026046 0.273916319 FVINYDYPNSSEDYIHR ddPTM_HeLa_Curcumin_4h_R1 3 FVINYDYPNSSEDYIHR 17 0 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 0 ;; ;; 130.02 0.00027336 59066000 8889.7 7200.5 7902.9 7142.1 8262.3 11687.6 9039 7829 9650.2 8019 FALSE FALSE TRUE 8186.070865 7822.879135 8195.788426 7112.547883 8163.777469 9263.460014 9292.610013 10216.02606 8591.597204 8297.659653 0.986551776 0.942781394 0.987722896 0.857175177 0.983865067 1.116394309 1.119907348 1.231193672 1.035424151 1 13.01848877 -5.015612318 2.010383461 0.978042919 1.186604325 0.742286321 0.050786491 0.131261052 1.014523709 0.007208542 0.028898569 9.65E-06 5.015612318 0.208561406 FVINYDYPNSSEDYVHR ddPTM_HeLa_Curcumin_4h_R1 2 FVINYDYPNSSEDYVHR 17 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 0 ; ; 121.45 0.00046609 16381700 6660.1 4608.7 5420.3 5483.8 6633 8802.5 6123.2 5798.6 7268.1 5731.4 FALSE FALSE TRUE 6132.946057 5007.055492 5621.181086 5461.109489 6553.905807 6976.762275 6295.000512 7566.566447 6470.807614 5930.565723 1.034124963 0.844279572 0.947832188 0.920841239 1.105106344 1.176407547 1.061450257 1.275859134 1.091094495 1 12.53395402 -5.583980309 5.478145955 0.990730103 1.157601732 0.55563206 0.079953111 0.121369099 7.251882053 0.011110872 0.0226509 2.61E-06 5.583980309 0.166871629 FVNVVPTFGK ddPTM_HeLa_Curcumin_4h_R1 2 FVNVVPTFGK 10 0 E9PR30;P62861 E9PR30 FAU 40S ribosomal protein S30 0 0 ; ; 152.28 8.51E-07 3471300 3430.8 3053.4 2910.9 3094.9 3257.4 3289.5 2863 2397.4 3066.3 2554.6 FALSE FALSE TRUE 3159.24856 3317.32229 3018.780515 3082.094124 3218.557632 2607.22062 2943.328075 3128.356224 2729.934562 2643.37216 1.195158445 1.254958473 1.142018729 1.165970562 1.217595343 0.986323704 1.11347472 1.18347173 1.03274696 1 11.36816384 -9.322562935 1.070394748 1.000858515 1.157285683 0.397595467 0.069028252 0.408415345 0.844715433 0.047227052 0.012780524 4.76E-10 9.322562935 0.156427167 FVNVVPTFGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 FVNVVPTFGKK 11 1 E9PR30;P62861 E9PR30 FAU 40S ribosomal protein S30 0 1 ; FVNVVPTFGK(1)K;FVNVVPTFGK(1)K 179.57 4.44E-12 95708000 16011.7 11209.7 14840.1 12664.4 12944.7 16811 14044.7 13968.5 13294.6 13666.4 FALSE TRUE FALSE 14744.35705 12178.61652 15390.08716 12611.99807 12790.34291 13324.2091 14438.75648 18227.43135 11836.21564 14141.30638 1.042644622 0.861208731 1.088307314 0.891855231 0.904466855 0.942219109 1.021034132 1.28894961 0.836995913 1 13.78762778 -4.267251699 4.249311726 0.992132494 1.31043533 0.54735116 0.085645297 0.108629329 4.482557548 0.009991501 0.103629177 5.40E-05 4.267251699 0.318302836 FVS(ph)EGDGGR ddPTM_HeLa_Curcumin_4h_R1 3 FVSEGDGGR 9 0 Q53EL6;Q53EL6-2 Q53EL6 PDCD4 Programmed cell death protein 4 1 0 FVS(1)EGDGGR;FVS(1)EGDGGR;FVS(1)EGDGGR ;; 92.239 0.01768 153030700 9379.9 7400.8 8222.3 8268.2 8026.7 7616.8 3836.49 6311.9 9244.5 7808.3 TRUE FALSE FALSE 8637.471017 8040.492175 8527.025671 8233.988379 7930.986845 6036.989821 3944.131584 8236.369254 8230.401479 8079.637844 1.069041854 0.995155022 1.055372262 1.019103645 0.981601775 0.747185695 0.488156977 1.019398321 1.018659702 1 12.98007491 -5.293213454 3.877281555 1.029963239 0.721417112 0.503844218 0.12168099 0.111273968 3.684107811 0.01559547 0.038513167 5.09E-06 5.293213454 -0.308546127 FVSEAELDER ddPTM_HeLa_Curcumin_4h_R1 1 FVSEAELDER 10 0 Q9GZU8;H3BQQ6;H3BTI2;H3BTP8;H3BSY6;H3BP64;H3BUL4;H3BMX9;H3BPH9;H3BPF9;H3BN22;Q6P4H7;H3BSF0 Q9GZU8 FAM192A;NIP30 Protein FAM192A 0 0 160.82 0.0051974 5020900 2691.2 2120.1 2502.4 2896.6 2713 3338.9 2487.8 2424 2877.4 2330.5 FALSE FALSE TRUE 2478.18868 2303.351997 2595.141145 2884.614637 2680.649247 2646.374503 2557.600972 3163.066441 2561.756419 2411.484702 1.027660959 0.955159282 1.076159075 1.196198605 1.11161777 1.097404641 1.06059183 1.311667637 1.06231502 1 11.23570594 -6.521312971 6.19150826 1.009189885 1.144075741 0.492115323 0.068699762 0.092750418 15.32567234 0.009736302 0.014263315 3.01E-07 6.521312971 0.134885856 FVTPVPGPQGK(ac)EGK ddPTM_HeLa_Curcumin_4h_R1 1 FVTPVPGPQGKEGK 14 1 O15014;E7ERY8;O15014-2 O15014 ZNF609 Zinc finger protein 609 0 1 FVTPVPGPQGK(1)EGK 135.6 3.02E-10 0 244.04 241.4 199.22 0 142.05 270.51 262.96 146.52 81.704 0 FALSE TRUE FALSE 224.7239765 262.2655403 206.6032685 0 140.3561465 214.4031767 270.3379499 191.1932735 72.74127561 0 0 FVYS(ph)LLWPR ddPTM_HeLa_Curcumin_4h_R1 1 FVYSLLWPR 9 0 C9JFR9;Q9UNU6 C9JFR9 CYP8B1 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase 1 0 FVY(0.334)S(0.666)LLWPR 96.19 0.015364 14120000 2307.5 1511.2 1706.5 1807.3 1740.3 2407.5 1803.6 1576.6 2134.2 1635.4 TRUE FALSE FALSE 2124.85894 1641.821394 1769.744391 1799.821871 1719.548059 1908.157362 1854.204162 2057.298082 1900.0836 1692.230028 1.25565609 0.970211713 1.045806044 1.063579916 1.016143214 1.12759928 1.095716381 1.215731932 1.122828202 1 10.72470997 -9.81800888 1.857235433 0.999591706 1.122055425 0 0.092029349 0.508739311 3.177880481 0.073765216 0.015219189 1.52E-10 9.81800888 0.122463719 FVYTCNECK(ac)HHVETR ddPTM_HeLa_Curcumin_4h_R1 2 FVYTCNECKHHVETR 15 1 A0A669KB12;Q09472;Q92793;Q92793-2 A0A669KB12;Q92793 EP300;CREBBP Histone acetyltransferase p300;CREB-binding protein 0 1 ; FVYTCNECK(1)HHVETR;FVYTCNECK(1)HHVETR 142.39 8.92E-05 161113000 8844.3 7612.6 7097.6 7907.9 8049.2 9012.6 7082.9 7544.9 7416.4 6746.6 FALSE TRUE FALSE 8144.264323 8270.599223 7360.6433 7875.179205 7953.218547 7143.285167 7281.627111 9845.305278 6602.839475 6981.043848 1.166625579 1.184722429 1.054375744 1.128080467 1.139259217 1.023240266 1.043057066 1.410291282 0.945824094 1 12.76922706 -9.334314585 0.989948665 0.997683292 1.135985314 0.28385215 0.105120464 0.725736963 1.239998096 0.072558387 0.017888127 4.63E-10 9.334314585 0.138302022 FWAWDPEEER ddPTM_HeLa_Curcumin_4h_R1 2 FWAWDPEEER 10 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 0 0 ; ; 199.89 8.99E-05 21447500 10182.5 7673.6 7643.6 8413.8 8028.1 11202.6 8739.9 7897.7 9043.2 8473.9 FALSE FALSE TRUE 9376.54438 8336.871791 7926.87854 8378.985925 7932.370151 8879.054481 8985.118072 10305.67237 8051.183585 8768.367394 1.069360345 0.950789516 0.904031296 0.955592478 0.904657594 1.012623454 1.024719616 1.17532397 0.918207829 1 13.09809253 -4.245471171 3.017376877 1.002821518 1.206875073 0.445628291 0.060022126 0.344225381 4.436453631 0.009312828 0.171103457 5.68E-05 4.245471171 0.204053555 FWAWDPEEERR ddPTM_HeLa_Curcumin_4h_R1 2 FWAWDPEEERR 11 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 0 0 ; ; 149.33 0.0010034 36460000 4730.2 3837.8 4339.6 4200.4 4616.8 5285.3 4214.8 4145.1 5065.3 4576.2 FALSE FALSE TRUE 4355.799679 4169.522331 4500.429394 4183.019858 4561.747675 4189.069202 4333.055944 5408.921908 4509.649263 4735.222609 0.919872208 0.880533541 0.950415591 0.883383993 0.963364989 0.884661514 0.915069111 1.14227405 0.952362673 1 12.20921654 -4.256575281 24.71579554 0.942539092 1.142274147 0.713307376 0.039819888 227.7001001 1156959.167 0.006689587 0.072797674 5.54E-05 4.256575281 0.199735055 FWEGDFHR ddPTM_HeLa_Curcumin_4h_R1 4 FWEGDFHR 8 0 B4DKY1;P49589-2;P49589;P49589-3 B4DKY1 CARS "Cysteine--tRNA ligase, cytoplasmic" 0 0 ;;; ;;; 148.99 0.0016388 42152400 20498.3 14570.8 17148.4 16842.6 18652.7 21634.9 16367.5 14851.3 18236.6 18756.3 FALSE FALSE TRUE 18875.83793 15830.23503 17783.93479 16772.90978 18430.27873 17147.57786 16826.728 19379.393 16236.09061 19408.08003 0.972576262 0.81565178 0.916316027 0.864223033 0.949618855 0.88352778 0.866996013 0.998521903 0.836563461 1 14.24436978 -7.473208479 13.72800689 0.98790887 0.898331502 0 0.067263646 1.653870002 456.8134628 0.007500035 0.008519858 3.36E-08 7.473208479 -0.089577369 LSS(ph)GFDDIDLPSAVK ddPTM_HeLa_Curcumin_4h_R1 2 LSSGFDDIDLPSAVK 15 0 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 0 LS(0.006)S(0.994)GFDDIDLPSAVK;LS(0.005)S(0.995)GFDDIDLPSAVK ; 186.29 1.77E-05 69045000 9420.8 5146.5 8642.7 7983.3 6633.3 8291.2 12947.4 27720 5816.3 6825.8 TRUE FALSE FALSE 8675.133739 5591.340528 8963.006065 7950.26722 6554.20223 6571.511659 13310.6692 36171.70039 5178.266442 7062.996042 1.228251253 0.791638632 1.269009074 1.125622494 0.927963458 0.930414178 1.884564159 5.121296993 0.733154374 1 12.78606457 -4.261988593 2.664674533 1.079052313 5.929010703 0.978561442 0.18241091 0.038325367 0.354324369 0.021510687 0.410472616 5.47E-05 4.261988593 4.84995839 up FWEVISDEHGIDPTGTYHGDSDLQLDR ddPTM_HeLa_Curcumin_4h_R1 6 FWEVISDEHGIDPTGTYHGDSDLQLDR 27 0 Q5JP53;P07437 Q5JP53 TUBB Tubulin beta chain 0 0 ;;;;; ;;;;; 176.22 6.03E-15 311161300 9424.79 8499.71 9002.52 7247.7 10756.61 18078.23 9804.21 9405.2 11631.48 8717.81 FALSE FALSE TRUE 8678.807927 9234.387058 9336.161311 7217.710938 10628.34445 14328.60131 10079.28975 12272.80218 10355.53574 9020.753249 0.962093485 1.02368248 1.034964715 0.800122865 1.178210307 1.588404085 1.11734458 1.36050747 1.147967964 1 13.13903219 -5.527288791 20.54084654 0.978619218 1.340227379 0.59470543 0.133474866 5.414743706 25220.71091 0.015912334 0.032013098 2.97E-06 5.527288791 0.36160816 FWEVISDEHGIDPTGTYHGDSDLQLER ddPTM_HeLa_Curcumin_4h_R1 2 FWEVISDEHGIDPTGTYHGDSDLQLER 27 0 P04350;M0QYM7;M0R0X0;M0QY85;M0QY37;M0QX14;M0R2D3;M0QZL7;M0R278;P68371 P04350;P68371 TUBB4A;TUBB4B Tubulin beta-4A chain;Tubulin beta-4B chain 0 0 ; ; 135.8 1.13E-08 7472800 1103.49 907.17 877.54 872.72 1061.37 2030.68 988.46 873.27 1493.27 889.28 FALSE FALSE TRUE 1016.147602 985.5817325 910.0624044 869.1089159 1048.713856 1609.494078 1016.193527 1139.526003 1329.462017 920.1824138 1.104289309 1.071072124 0.98900217 0.944496333 1.139680394 1.749103279 1.104339218 1.238369682 1.444780945 1 9.845776074 -5.50931345 24.9890557 1.040703398 1.355713296 0.243511213 0.203357765 417.949064 769916.4354 0.021560971 0.046343881 3.10E-06 5.50931345 0.315009898 FY(ph)DGQLVLTS(ph)DIWLCLKCGFQGCGK ddPTM_HeLa_Curcumin_4h_R1 1 FYDGQLVLTSDIWLCLKCGFQGCGK 25 1 H0Y8J5;D6RBV3;D6RC01;E2QRF0;Q70EL2-2;Q70EL2 H0Y8J5 USP45 Ubiquitinyl hydrolase 1;Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 45 2 0 FY(0.985)DGQLVLT(0.219)S(0.796)DIWLCLKCGFQGCGK 44.5 0.0095131 0 1026.7 718.54 683.22 773.12 985.81 920.68 758.85 834.5 723.06 779.14 TRUE FALSE FALSE 945.4356116 780.6473958 708.5407342 769.9210343 974.0548596 729.7205898 780.1412887 1088.935208 643.742127 806.215057 1.172684141 0.968286798 0.878848302 0.954982207 1.208182421 0.905119029 0.967659041 1.350675851 0.798474453 1 9.655020917 -4.252206112 24.14354322 1.044549445 1.350676115 0.337777885 0.131293543 638.9554683 1670709.411 0.01636419 0.266185662 5.59E-05 4.252206112 0.30612667 FY(ph)S(ph)LPAEET(ph)PVS(ph)LPK ddPTM_HeLa_Curcumin_4h_R1 1 FYSLPAEETPVSLPK 15 0 H3BS47;A0A087WX34;H3BV03;Q68CZ1-2;Q68CZ1 H3BS47 RPGRIP1L Protein fantom 4 0 FY(1)S(1)LPAEET(1)PVS(1)LPK 52.372 0.018949 43482000 1505.8 1064.5 1016.7 1348.1 1195.3 1420.2 1321 1098.2 1266.7 1108.8 TRUE FALSE FALSE 1386.614341 1156.510637 1054.379796 1342.521919 1181.046828 1125.634511 1358.063705 1433.036125 1127.746179 1147.330717 1.208556801 1.00800111 0.918985067 1.170126363 1.029386567 0.981089841 1.183672401 1.249017483 0.982930346 1 10.16406559 -4.568793921 7.233065752 1.075098872 1.233383537 0.339896983 0.090024892 0.188588831 23.8927039 0.014247843 0.054754172 2.70E-05 4.568793921 0.158284665 FY(ph)VINY(ph)LELGK ddPTM_HeLa_Curcumin_4h_R1 1 FYVINYLELGK 11 0 C9JH62;Q9NRM2 C9JH62 ZNF277 Zinc finger protein 277 2 0 FY(1)VINY(1)LELGK 54.259 0.018298 3116900 2538.1 2153.5 2019.9 2013.9 2445.2 2724.4 2231 1520.1 2501.3 2146.1 TRUE FALSE FALSE 2337.206707 2339.638944 2094.759271 2005.567015 2416.042587 2159.32873 2293.595856 1983.571492 2226.913648 2220.676815 1.052474944 1.053570213 0.943297672 0.903133226 1.087975779 0.97237415 1.032836404 0.893228352 1.002808528 1 11.11678373 -6.766840658 24.99963679 1.02763149 0.977038923 0.183542861 0.056335194 184.5552973 854207.0797 0.008888084 0.011869658 1.71E-07 6.766840658 -0.050592567 FYCDYCDTYLTHDS(ph)PSVR ddPTM_HeLa_Curcumin_4h_R1 1 FYCDYCDTYLTHDSPSVR 18 0 A0A0A0MRR7;P09234 A0A0A0MRR7 SNRPC U1 small nuclear ribonucleoprotein C 1 0 FYCDYCDTY(0.001)LT(0.021)HDS(0.88)PS(0.098)VR 118.08 0.00019395 13736000 1418.2 1306.9 1333.9 1544.6 1368.4 2362.2 1693.3 710.32 1199.2 1068.8 TRUE FALSE FALSE 1305.947974 1419.862613 1383.335507 1538.208854 1352.082724 1872.253093 1740.809441 926.8932981 1067.65076 1105.94072 1.180848077 1.283850559 1.250822473 1.39086013 1.222563469 1.692905468 1.574053119 0.838103961 0.965377927 1 10.11105834 -7.650117052 0.563639524 1.018212173 1.374926877 0.27453007 0.21545186 0.671475378 0.50185218 0.083940365 0.072392058 2.24E-08 7.650117052 0.356714704 FYDPS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 1 FYDPSPPR 8 0 Q3V6T2;Q3V6T2-3;Q3V6T2-2;Q3V6T2-4;Q3V6T2-5;A0A2U3TZV9;A0A2R8Y7B1;A0A2R8Y7D4;H7C2C6;A0A2R8Y820;A0A2R8Y885;A0A2R8YCU9;A0A2R8YDS8;H0Y470;H0Y7U8;A0A2R8Y5D7;H0Y7K3;A0A2R8Y4X4;A0A2R8Y4W8;A0A2R8YG73;A0A2R8Y802 Q3V6T2 CCDC88A Girdin 1 0 FYDPS(1)PPR 101.46 0.014198 14153000 9189.3 7270.8 7660.4 7799.8 7931.4 9524.6 6965.5 3870.3 8770.2 7218.1 TRUE FALSE FALSE 8461.957208 7899.255554 7944.301163 7767.526494 7836.823235 7549.090596 7160.933183 5050.336653 7808.131002 7468.928438 1.132954651 1.057615643 1.06364671 1.039978701 1.049256704 1.010732752 0.958763127 0.676179548 1.045415158 1 12.86668556 -3.788962843 1.162687898 1.061707936 4.42E-20 0.924293348 0.032286354 1.111547653 0.579153403 0.00726837 1.870899258 0.000162569 3.788962843 -1.061707936 FYDS(ph)NTVK ddPTM_HeLa_Curcumin_4h_R1 2 FYDSNTVK 8 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 0 FYDS(0.935)NT(0.065)VK;FYDS(0.817)NT(0.183)VK ; 130.01 0.003483 16339000 6444 5154.4 5927.2 7044.2 6056.2 8257.5 6878.4 4499.4 6654.4 6198.8 TRUE FALSE FALSE 5933.9506 5599.923368 6146.867246 7015.052967 5983.98377 6544.801419 7071.389392 5871.246347 5924.428968 6414.207839 0.925126025 0.873049878 0.95832056 1.093674097 0.932926391 1.020360048 1.102457165 0.915350187 0.923641565 1 12.64705539 -6.474435989 24.99805703 0.95482826 1.015102114 0.240435761 0.064123651 540.8835264 279113.7777 0.009900769 0.015123469 3.35E-07 6.474435989 0.060273855 FYEAFSK ddPTM_HeLa_Curcumin_4h_R1 1 FYEAFSK 7 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 0 126.67 0.0088512 16167000 5262.8 3555.6 4836 4413.2 4684.5 6835.9 5400.4 4876.7 4685.3 4742.3 FALSE FALSE TRUE 4846.243827 3862.930221 5015.226414 4394.939348 4628.640397 5418.057284 5551.92069 6363.58338 4171.334312 4907.094572 0.987599435 0.787213322 1.022035818 0.895629641 0.943254777 1.104127341 1.131406906 1.296812867 0.850061936 1 12.26065336 -4.589419485 1.341565228 0.97037955 1.326033537 0.67294482 0.08061125 0.3432767 0.802406596 0.010711783 0.140380204 2.57E-05 4.589419485 0.355653988 FYEEFDAHGR ddPTM_HeLa_Curcumin_4h_R1 1 FYEEFDAHGR 10 0 K7EIT8;A8MX75;P18074-2;P18074 K7EIT8 ERCC2 TFIIH basal transcription factor complex helicase XPD subunit 0 0 123.96 0.0013206 0 1674.5 1716.5 1753.5 1607.3 1585.7 2271.2 1415 995.95 2021.4 1683.1 FALSE FALSE TRUE 1541.961558 1864.866611 1818.486253 1600.649418 1566.791563 1800.127518 1454.701092 1299.61057 1799.657477 1741.5876 0.885376973 1.070785421 1.044154341 0.919074882 0.899634083 1.033612962 0.835272996 0.746221764 1.03334307 1 10.76618733 -4.567669149 4.895113834 0.960054015 0.764183449 0.577252252 0.06571193 0.103834955 5.506040063 0.009607419 0.040805827 2.71E-05 4.567669149 -0.195870566 FYEEVHDLER ddPTM_HeLa_Curcumin_4h_R1 6 FYEEVHDLER 10 0 F8VRJ2;F5H4R6;H0YHC3;F8W020;F8W118;F8VXI6;F8VUX1;F8VY35;P55209;F8VV59;B7Z9C2;H0YIV4;F8W0J6;P55209-3;P55209-2;F8W543;H0YH88;F8VVB5;C9J6D1;Q99733;Q99733-2;E9PNJ7;A8MXH2;E9PKT8;C9JZI7;E9PS34;E9PNW0;E9PJJ2 F8VRJ2;C9J6D1 NAP1L1;NAP1L4 Nucleosome assembly protein 1-like 1;Nucleosome assembly protein 1-like 4 0 0 ;;;;; ;;;;; 193.83 6.27E-05 845688200 55481.7 44077.7 48308.8 46883.9 51674.1 63305.8 49948.4 50308.7 50767.4 45762 FALSE FALSE TRUE 51090.2649 47887.57998 50099.16662 46689.90684 51057.92011 50175.46348 51349.81767 65647.59104 45198.34323 47352.22609 1.078941142 1.011305781 1.0580108 0.986012923 1.078258074 1.059622062 1.084422464 1.386367579 0.954513588 1 15.53114463 -4.177258719 2.308713805 1.03779682 1.524456638 0.875460265 0.040148904 0.183130816 0.932287765 0.004987022 0.194374931 6.65E-05 4.177258719 0.486659818 FYEEVHDLERK ddPTM_HeLa_Curcumin_4h_R1 3 FYEEVHDLERK 11 1 F8VRJ2;F5H4R6;H0YHC3;F8W020;F8W118;F8VXI6;F8VUX1;F8VY35;P55209;F8VV59;B7Z9C2;H0YIV4;F8W0J6;P55209-3;P55209-2;F8W543;H0YH88;F8VVB5;C9J6D1;Q99733;Q99733-2;E9PNJ7;A8MXH2;E9PKT8;C9JZI7;E9PS34;E9PNW0;E9PJJ2 F8VRJ2;C9J6D1 NAP1L1;NAP1L4 Nucleosome assembly protein 1-like 1;Nucleosome assembly protein 1-like 4 0 0 ;; ;; 99.973 0.0032191 44002600 17329.5 11874.88 11699.74 13581.26 9995.8 16952.38 12237.86 13943.9 20206.1 16986.2 FALSE FALSE TRUE 15957.85179 12901.29171 12133.34266 13525.06434 9876.606613 13436.2653 12581.22142 18195.33092 17989.54138 17576.46919 0.90790998 0.734009293 0.690317408 0.769498367 0.561922108 0.764446212 0.715799134 1.035209673 1.023501432 1 14.10135767 -7.429527532 2.23136934 0.964980436 0.741907706 0.448906374 0.113841366 0.198257767 1.897019893 0.020462809 0.022831785 3.72E-08 7.429527532 -0.22307273 FYEQFSK ddPTM_HeLa_Curcumin_4h_R1 2 FYEQFSK 7 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 ; ; 116.37 0.0099057 21987000 9518.9 7959.6 8556.2 7875.9 8005.9 12340 9599.4 9136.1 8850.8 7317.5 FALSE FALSE TRUE 8765.469021 8647.592357 8873.300299 7843.311613 7910.434871 9780.5449 9868.733329 11921.65483 7879.889384 7571.78258 1.157649329 1.142081441 1.17189053 1.035860648 1.04472557 1.291709686 1.30335667 1.574484569 1.040691449 1 12.88641727 -4.111553609 0.870903671 1.08216119 1.948782193 0.837182091 0.067042702 0.925118863 0.435303561 0.012664681 0.811394561 7.73E-05 4.111553609 0.866621003 FYEQMNGPVAGASR ddPTM_HeLa_Curcumin_4h_R1 1 FYEQMNGPVAGASR 14 0 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;P29692-4;E9PQZ1;E9PL12;E9PPR1;E9PK06;E9PIZ1;E9PK72;E9PKK3;E9PMW7;E9PN91;H0YCK7 P29692;E9PMW7 EEF1D Elongation factor 1-delta 0 0 208.33 1.34E-08 11452000 595.68 416.05 460.5 291.42 644.65 547.81 438.5 532.25 453.53 433.81 FALSE FALSE TRUE 548.5312994 452.0115081 477.5665351 290.2141813 636.9629698 434.1880309 450.8031298 694.5305748 403.7788937 448.8848652 1.221986621 1.006965356 1.063895382 0.646522536 1.418989632 0.967259234 1.0042734 1.547235446 0.899515499 1 8.810201644 -4.256187526 24.43153618 1.073718463 1.547235724 0.370814575 0.194982498 338.5667721 1574935.565 0.024927318 0.281149915 5.54E-05 4.256187526 0.47351726 FYGDEEK(ac)DK ddPTM_HeLa_Curcumin_4h_R1 1 FYGDEEKDK 9 1 P27797;K7EJB9 P27797 CALR Calreticulin 0 1 FYGDEEK(1)DK 157.96 3.91E-08 6239400 2575.4 3485.4 2503.6 2831.8 6145.9 6418.1 5735 4246.6 5333.8 2113.1 FALSE TRUE FALSE 2371.554372 3786.662445 2596.385618 2820.082762 6072.614157 5086.913713 5895.908665 5541.368791 4748.695485 2186.530068 1.08462006 1.731813571 1.18744565 1.289752564 2.777283627 2.326477824 2.69646814 2.534320873 2.17179519 1 11.09442747 -5.809922968 5.799655823 1.121278036 2.573970239 0.632270236 0.404131784 0.043279105 3.286233421 0.036681402 0.068026933 1.55E-06 5.809922968 1.452692203 FYHDWNDKEIEVLNK ddPTM_HeLa_Curcumin_4h_R1 2 FYHDWNDKEIEVLNK 15 1 J3KQ32;Q9NTK5-2;Q9NTK5;C9JCJ9;Q9NTK5-3 J3KQ32 OLA1 Obg-like ATPase 1 0 0 ; ; 85.271 0.0053261 45357000 8581.7 6545.7 7988.4 7053.1 7453.6 11584.3 7778.1 7863.6 8986.6 7381.6 FALSE FALSE TRUE 7902.44939 7111.481141 8284.457131 7023.916141 7364.720688 9181.585598 7996.332552 10261.17544 8000.792463 7638.110051 1.034607951 0.931052459 1.084621336 0.919588235 0.964207198 1.202075584 1.046899364 1.343418119 1.047483266 1 12.89899999 -1.000000542 0.793966316 1.008078738 78.80441549 0.636752354 0.074095847 205.0975209 0.689998694 0.010724993 28702.41275 0.099999875 1.000000542 77.79633675 RNS(ph)SSPVSPAS(ph)VPGQR ddPTM_HeLa_Curcumin_4h_R1 1 RNSSSPVSPASVPGQR 16 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 2 0 RNS(0.602)S(0.271)S(0.123)PVS(0.195)PAS(0.809)VPGQR 113.14 0.0021334 18288000 5117.1 4410.3 5093.9 4676.6 5208.7 5014 2818.1 1276.5 5035 5061.7 TRUE FALSE FALSE 4712.076135 4791.50668 5282.684415 4657.249468 5146.589654 3974.039881 2897.168301 1665.698974 4482.673097 5237.593698 0.899664313 0.914829778 1.008609052 0.889196401 0.982624837 0.75875299 0.55314873 0.318027527 0.855864994 1 12.35468843 -4.633324216 1.377866053 0.951868624 0.250889472 0.936987217 0.052818447 0.103238229 0.270368536 0.00726195 0.08285431 2.33E-05 4.633324216 -0.700979152 down GAAAHPDSEEQQQR ddPTM_HeLa_Curcumin_4h_R1 3 GAAAHPDSEEQQQR 14 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 ;; ;; 136.27 0.00013964 3240750 1490.89 934.29 926.82 1195.25 1214.66 1298.74 1169.63 1125.07 1427.57 1012.64 FALSE FALSE TRUE 1372.884483 1015.045864 961.1687645 1190.304372 1200.175973 1029.366684 1202.44667 1468.098664 1270.969143 1047.829165 1.310217858 0.968713125 0.917295297 1.13597179 1.145392792 0.982380257 1.147559841 1.401085896 1.21295454 1 10.03318781 -4.277934395 4.354738114 1.109470543 1.418337671 0.379942822 0.117526582 0.199793033 8.86915946 0.019896164 0.184079216 5.27E-05 4.277934395 0.308867127 GAADACTTEK(ac)SNK ddPTM_HeLa_Curcumin_4h_R1 2 GAADACTTEKSNK 13 1 Q9Y3Y4-2;Q9Y3Y4 Q9Y3Y4-2 PYGO1 Pygopus homolog 1 0 1 ; GAADACTTEK(1)SNK;GAADACTTEK(1)SNK 237.53 1.26E-38 2084280 850.17 714.88 471.22 881.23 761.37 916.38 486.13 637.15 632.9 805.77 FALSE TRUE FALSE 782.8781474 776.6710418 488.6838277 877.5837038 752.29116 726.3124583 499.7694994 831.4141019 563.4724534 833.7704475 0.938961257 0.931516635 0.586113155 1.052548344 0.902276115 0.871118016 0.599408987 0.997173868 0.675812455 1 9.703506427 -6.983175886 24.99920068 0.969284749 0.832037372 0 0.168801523 304.4909009 452446.1862 0.021467148 0.028209648 1.04E-07 6.983175886 -0.137247376 GAADEVEVEPPEPPGPVAS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 GAADEVEVEPPEPPGPVASR 20 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 0 GAADEVEVEPPEPPGPVAS(1)R;GAADEVEVEPPEPPGPVAS(1)R ; 257.83 5.01E-44 5385200 1853.16 2007.86 2239 1899 2449.01 2662.9 2278.65 2356.47 1963.83 1986.43 TRUE FALSE FALSE 1706.480431 2181.410472 2321.97931 1891.142441 2419.807155 2110.584523 2342.582786 3074.946855 1748.402762 2055.458295 0.830218952 1.061276931 1.129665007 0.920058775 1.177259184 1.026819434 1.139688795 1.495990876 0.850614565 1 11.00524438 -1 0.480553634 0.938624656 15.26111194 0.68777328 0.102404753 38.23307403 0.385279482 0.022330792 551.0244707 0.1 1 14.32248728 GAAEEAELEDS(ph)DDEEKPVK ddPTM_HeLa_Curcumin_4h_R1 2 GAAEEAELEDSDDEEKPVK 19 1 Q9UBB9;F6XM96 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 1 0 GAAEEAELEDS(1)DDEEKPVK;GAAEEAELEDS(1)DDEEKPVK ; 77.469 0.0024037 25335000 4017.1 3791 4009.2 4036.3 4674.3 4272 4049.6 3154.7 3451.7 3775.6 TRUE FALSE FALSE 3699.142296 4118.677148 4157.784479 4019.59886 4618.562025 3385.939045 4163.220877 4116.553508 3073.057146 3906.801819 0.946846671 1.054232423 1.064242486 1.028871964 1.182184876 0.866677964 1.065634007 1.053688848 0.786591511 1 11.93177236 -7.251694991 23.91558456 0.974899817 1.044392657 0.223067004 0.094188943 490.889633 1204785.438 0.01162876 0.014137882 5.60E-08 7.251694991 0.06949284 GAAEEAELEDS(ph)DDEEKPVKQDDFPK ddPTM_HeLa_Curcumin_4h_R1 1 GAAEEAELEDSDDEEKPVKQDDFPK 25 2 Q9UBB9;F6XM96 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 1 0 GAAEEAELEDS(1)DDEEKPVKQDDFPK 56.021 0.0021889 116280000 2862 2574.7 3282.5 3186.5 3279.3 3218.1 2851.5 2208.1 2656.9 2853.3 TRUE FALSE FALSE 2635.46968 2797.245595 3404.152338 3173.315107 3240.196489 2550.629785 2931.505416 2881.339525 2365.444717 2952.451963 0.892637616 0.947431366 1.152991609 1.074806685 1.097459512 0.863902213 0.992905372 0.975914109 0.801179747 1 11.52769787 -10.17561818 3.576266223 1.000890334 0.973982878 0 0.107963884 1.613474902 38.22269284 0.092508029 0.014050809 6.67E-11 10.17561818 -0.026907456 GAAEEAELEDS(ph)DDEEKPVKQDDFPKDFGPR ddPTM_HeLa_Curcumin_4h_R1 1 GAAEEAELEDSDDEEKPVKQDDFPKDFGPR 30 3 Q9UBB9;F6XM96 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 1 0 GAAEEAELEDS(1)DDEEKPVKQDDFPKDFGPR 87.196 6.15E-07 15889000 3059.5 2121.3 2667.1 2848.7 2390.7 3455.7 2589.3 2073.5 3335.1 2878.8 TRUE FALSE FALSE 2817.337347 2304.65572 2765.945072 2836.912834 2362.192464 2738.948866 2661.948789 2705.700605 2969.247874 2978.838086 0.945783982 0.773676062 0.928531526 0.9523555 0.792991225 0.919468862 0.893619832 0.908307376 0.996780553 1 11.54053399 -7.492355897 8.686262876 0.976252849 0.882607124 0.419332302 0.054775938 0.205830606 52.7223641 0.009340248 0.010333475 3.22E-08 7.492355897 -0.093645725 GAAIPAK(ac)GAK ddPTM_HeLa_Curcumin_4h_R1 2 GAAIPAKGAK 10 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 ; GAAIPAK(1)GAK;GAAIPAK(1)GAK 138.54 0.00028331 17033600 18740.9 11122.8 15949.7 14423.2 16841.5 19386.4 16936 14862.2 15494 14415.7 FALSE TRUE FALSE 17257.53799 12084.20527 16540.80991 14363.52062 16640.67611 15365.44211 17411.17858 19393.61636 13794.34696 14916.6445 1.15693164 0.810115524 1.108882759 0.962919014 1.11557771 1.030087035 1.167231583 1.300132638 0.924762064 1 13.86463542 -4.436620522 2.235622287 1.051501116 1.321681268 0.414374546 0.102280003 0.347121448 2.568096019 0.013869678 0.158309076 3.66E-05 4.436620522 0.270180151 GAANASGSS(ph)PDAPAK ddPTM_HeLa_Curcumin_4h_R1 4 GAANASGSSPDAPAK 15 0 E7EPJ7;O75962-5;O75962-4;O75962 E7EPJ7 TRIO Triple functional domain protein 1 0 GAANASGS(0.209)S(0.791)PDAPAK;GAANASGS(0.111)S(0.889)PDAPAK;GAANASGS(0.18)S(0.82)PDAPAK;GAANASGS(0.103)S(0.896)PDAPAK ;;; 245.04 2.60E-29 109519000 22197.7 20772.2 22670.2 20909.6 25745.6 21176.1 17748.4 10217 18033.6 17207.5 TRUE FALSE FALSE 20440.72862 22567.65641 23510.37755 20823.08162 25438.60054 16783.93816 18246.37234 13332.11627 16055.3592 17805.45934 1.148003442 1.267457131 1.320402754 1.169477362 1.428696673 0.942628765 1.024762798 0.748765646 0.901709913 1 14.12003203 -4.298594354 1.542519858 1.13104364 0.635320232 0.382520174 0.156109528 0.89428759 2.058397839 0.022796177 0.654456477 5.03E-05 4.298594354 -0.495723408 GAANASGSS(ph)PDAPAKDAR ddPTM_HeLa_Curcumin_4h_R1 3 GAANASGSSPDAPAKDAR 18 1 E7EPJ7;O75962-5;O75962-4;O75962 E7EPJ7 TRIO Triple functional domain protein 1 0 GAANASGS(0.015)S(0.985)PDAPAKDAR;GAANASGS(0.064)S(0.936)PDAPAKDAR;GAANAS(0.002)GS(0.152)S(0.846)PDAPAKDAR ;; 149.24 0.00013333 76388500 11390.7 8996 9926.4 10923.5 9144.4 10971.9 7282.2 5138.3 11591.1 10908.5 TRUE FALSE FALSE 10489.11408 9773.574155 10294.28112 10878.30145 9035.359002 8696.204261 7486.518933 6704.944016 10319.58533 11287.56956 0.929262408 0.865870558 0.912001566 0.963741698 0.80046984 0.770423094 0.663253404 0.594011313 0.914243343 1 13.46244726 -3.521645964 0.367054269 0.97789048 2.72E-15 0.883174035 0.043015144 1.956856932 0.121665077 0.01214925 0.945106137 0.000300853 3.521645964 -0.97789048 GAAPGSQTGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 GAAPGSQTGKK 11 1 H0YM74;Q92610 H0YM74 ZNF592 Zinc finger protein 592 0 1 ; GAAPGSQTGK(1)K;GAAPGSQTGK(1)K 113.93 0.0011154 1576790 889.53 1021.99 1174.69 1014.91 841.84 726.2 487.47 586.32 849.84 1095.25 FALSE TRUE FALSE 819.1227619 1110.326262 1218.225045 1010.710571 831.8016078 575.577934 501.1470962 765.0862689 756.6146782 1133.309856 0.722770351 0.979719938 1.074926719 0.89182192 0.733957799 0.507873404 0.442197775 0.675090104 0.667615016 1 10.14632664 -5.493379263 2.930629015 0.893474104 0.532881341 0.598807632 0.127293452 0.140043709 2.405374141 0.019785321 0.046365408 3.21E-06 5.493379263 -0.360592763 GAAPIAK ddPTM_HeLa_Curcumin_4h_R1 1 GAAPIAK 7 0 A0A087WZE6 A0A087WZE6 GCNT7 0 0 113.82 0.011388 6762100 6326.5 5723.9 5375.1 4953.8 5583.6 6369.7 5421.7 5741.6 5576.2 6383 FALSE FALSE TRUE 5825.750849 6218.648411 5574.305934 4933.302488 5517.019217 5048.552419 5573.81831 7492.187409 4964.504811 6604.808775 0.882046861 0.941533453 0.843976885 0.746925862 0.835303399 0.764375259 0.843903056 1.134353418 0.751650045 1 12.68930108 -8.761630582 0.590812455 1.004912739 0.859400552 0 0.12750538 1.12910411 0.732401104 0.082216007 0.025587254 1.73E-09 8.761630582 -0.145512187 GAAPNVVYTYTGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GAAPNVVYTYTGKR 14 1 F8WJN3;Q16630-3;Q16630;Q16630-2;F8W084;A0A3B3ISW1 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 0 1 ; GAAPNVVYTYTGK(1)R;GAAPNVVYTYTGK(1)R 171.62 1.14E-05 5246300 410.89 301.52 404.65 332.38 356.28 508.4 287.69 251.112 437.9 430.06 FALSE TRUE FALSE 378.3676229 327.5820453 419.646685 331.0046996 352.0315937 402.9521092 295.7618071 327.6748928 389.8634656 445.004553 0.850255622 0.736131896 0.94301661 0.743823175 0.791074139 0.905501093 0.664626474 0.73634054 0.876088712 1 8.797676287 -13.52287873 0.094003916 1.720903023 0.621849048 0.315881509 0.084145893 69.49239102 0.491945688 9.887248477 0.763576679 3.00E-14 13.52287873 -1.099053975 GAAQENGAPECS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 GAAQENGAPECSPR 14 0 Q6IE81;Q6IE81-2;Q6IE81-3 Q6IE81 JADE1 Protein Jade-1 1 0 GAAQENGAPECS(1)PR;GAAQENGAPECS(1)PR ; 109.07 0.0044647 2987000 3211.7 3677.3 2797.6 3346.2 2485.8 3353.5 2462 1687.21 3027 3748.1 TRUE FALSE FALSE 2957.490556 3995.149426 2901.281517 3332.354311 2456.158459 2657.946298 2531.077094 2201.632562 2694.945673 3878.346196 0.762564868 1.030116762 0.748071825 0.859220436 0.633300467 0.685329819 0.652617628 0.567673037 0.694869807 1 11.92122587 -3.079672733 0.127878866 1.06601147 6.09E-16 0.314526118 0.121351894 23.96748604 0.355366367 0.422218968 4.413160867 0.000832391 3.079672733 -1.06601147 GAAS(ph)PVPPPLVR ddPTM_HeLa_Curcumin_4h_R1 2 GAASPVPPPLVR 12 0 Q4G0W2 Q4G0W2 DUSP28 Dual specificity phosphatase 28 1 0 GAAS(1)PVPPPLVR;GAAS(1)PVPPPLVR ; 99.752 0.0094383 9827300 4506.3 3594.9 3887.2 3890 3521.9 3367.7 2471.89 1393.78 4095.7 3545.1 TRUE FALSE FALSE 4149.6216 3905.627137 4031.263052 3873.904211 3479.903643 2669.201058 2541.244581 1818.737106 3646.411957 3668.291961 1.131213558 1.064699097 1.098948256 1.056051223 0.948644132 0.727641389 0.69275963 0.495799442 0.99403537 1 11.84089275 -5.056985292 1.164719853 1.068984191 0.519986725 0.933739242 0.051312136 0.117998165 0.260696896 0.009026735 0.055290811 8.77E-06 5.056985292 -0.548997466 GAASAMDLRQT(ph)SKS(ph)T(ph)MKIK ddPTM_HeLa_Curcumin_4h_R1 1 GAASAMDLRQTSKSTMKIK 19 3 F8W771 F8W771 PMFBP1 3 0 GAAS(0.029)AMDLRQT(0.952)S(0.163)KS(0.861)T(0.996)MKIK 55.864 0.013592 15224000 1589.6 1326.3 1816 1426.7 1473 1577.5 1121.1 685.78 1612.2 1331.3 TRUE FALSE FALSE 1463.781483 1440.939462 1883.302558 1420.796693 1455.435437 1250.308718 1152.555049 894.8711651 1435.345694 1377.562576 1.062588015 1.046006539 1.367126685 1.031384504 1.056529455 0.9076239 0.836662573 0.64960473 1.041945911 1 10.42790214 -4.616525145 1.290137648 1.059635068 0.609211132 0.65848914 0.102016559 0.409791643 0.887521059 0.016024657 0.204458412 2.42E-05 4.616525145 -0.450423936 S(ph)LDYLNLDK ddPTM_HeLa_Curcumin_4h_R1 1 SLDYLNLDK 9 0 Q96GV9 Q96GV9 C5orf30 UNC119-binding protein C5orf30 1 0 S(1)LDYLNLDK 147.24 0.0018882 14491000 3485.9 3027.7 3260 3285.5 3068.4 3096.1 1784.9 773.67 3402.5 3016.8 TRUE FALSE FALSE 3209.987337 3289.400897 3380.818468 3271.905472 3031.811334 2453.93396 1834.97949 1009.558421 3029.254263 3121.633575 1.028303694 1.053743438 1.083028609 1.048138865 0.971225886 0.786105704 0.587826677 0.323407087 0.97040674 1 11.60808549 -4.632559073 1.192280761 1.026144622 0.22319982 0.978988218 0.034188115 0.085455183 0.152540293 0.005385205 0.071716443 2.33E-05 4.632559073 -0.802944803 down GAASTLVPGVSET(ph)S(ph)ASPGSPSVR ddPTM_HeLa_Curcumin_4h_R1 1 GAASTLVPGVSETSASPGSPSVR 23 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 2 0 GAAS(0.001)TLVPGVS(0.295)ET(0.697)S(0.502)AS(0.502)PGS(0.003)PSVR 122.52 2.34E-05 3056500 1673.4 1327.3 1421.2 1402.7 1580.2 1701.6 1700.3 981.6 1593.7 1369.6 TRUE FALSE FALSE 1540.948624 1442.025898 1473.870922 1396.895999 1561.357147 1348.668979 1748.005842 1280.885321 1418.875097 1417.193498 1.087324085 1.017522236 1.039992721 0.98567768 1.101724746 0.951647733 1.233427788 0.903818232 1.00118657 1 10.46882104 -5.754758229 24.98643895 1.036644301 1.054066477 0.001660046 0.086976368 936.8921721 3503796.072 0.011505071 0.022552619 1.76E-06 5.754758229 0.017422176 VVPS(ph)PLQFCAATPK ddPTM_HeLa_Curcumin_4h_R1 1 VVPSPLQFCAATPK 14 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 0 VVPS(1)PLQFCAATPK 88.768 0.011099 61728000 6249.3 4192.6 5279.3 5176.6 4746.7 4719.1 2728.1 723.1 6338.4 5445.8 TRUE FALSE FALSE 5754.661311 4554.989662 5474.955502 5155.180601 4690.098703 3740.305465 2804.643144 943.5698613 5643.093378 5635.041145 1.021227914 0.808332991 0.971591043 0.914843471 0.832309575 0.663758324 0.497714759 0.167446845 1.001428957 1 12.46021043 -4.630464588 0.778547979 0.994562626 1.04E-23 0.942883314 0.062405959 0.261398573 0.15517277 0.010510534 0.200817103 2.34E-05 4.630464588 -0.994562626 down GACAGSEDAVK ddPTM_HeLa_Curcumin_4h_R1 1 GACAGSEDAVK 11 0 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 154.56 2.43E-07 2125900 1170.4 1093.4 1141 1135.2 1142.5 1369.4 1011.6 979.72 1403.6 1220.5 FALSE FALSE TRUE 1077.761605 1187.908624 1183.286464 1130.502843 1128.876434 1085.371004 1039.982773 1278.432118 1249.628592 1262.912284 0.853393873 0.940610555 0.936950633 0.895155473 0.893867648 0.859419152 0.823479814 1.012288925 0.989481698 1 10.30253872 -9.476219907 1.155793973 1.001324584 0.895060784 0.341671882 0.05078556 0.420689614 0.985067746 0.036521145 0.008511356 3.34E-10 9.476219907 -0.106263799 GADAGSSGGTGPTEGY(ph)SPPAASTR ddPTM_HeLa_Curcumin_4h_R1 1 GADAGSSGGTGPTEGYSPPAASTR 24 0 J3KT76;J3KSI9;Q969W3;Q969W3-2 J3KT76 FAM104A Protein FAM104A 1 0 GADAGSSGGTGPT(0.002)EGY(0.59)S(0.408)PPAASTR 123.72 5.45E-06 16892000 1095.8 982.88 957.88 1114.1 1103.6 1097 914.59 776.72 1023 1122.1 TRUE FALSE FALSE 1009.066274 1067.835768 993.3798754 1109.490149 1090.440291 869.4698343 940.2509339 1013.538352 910.7794594 1161.092891 0.86906593 0.919681599 0.855555901 0.95555675 0.939149915 0.748837445 0.8097982 0.872917542 0.784415671 1 10.18126768 -13.52287875 0.135535967 1.462425108 0.810340358 0 0.085806086 53.42153012 0.508128435 6.67948787 0.186909562 3.00E-14 13.52287875 -0.65208475 GADAGSSGGTGPTEGYS(ph)PPAASTR ddPTM_HeLa_Curcumin_4h_R1 2 GADAGSSGGTGPTEGYSPPAASTR 24 0 J3KT76;J3KSI9;Q969W3;Q969W3-2 J3KT76 FAM104A Protein FAM104A 1 0 GADAGSSGGTGPT(0.035)EGY(0.003)S(0.961)PPAASTR;GADAGSSGGTGPT(0.006)EGYS(0.994)PPAASTR ; 184.68 1.93E-11 44205000 3760.7 3483.5 3832.2 3936.2 4096.7 4393.3 3848.7 4430.7 4549.3 3797.4 TRUE FALSE FALSE 3463.036627 3784.598218 3974.224703 3919.913047 4047.849528 3482.080057 3956.684164 5781.600034 4050.253172 3929.359367 0.881323469 0.963159096 1.011417977 0.997595964 1.030155084 0.886169915 1.006954008 1.471384898 1.030766798 1 11.9400784 -4.266057492 4.102473273 0.955584603 1.512846047 0.883317539 0.053452026 0.053748808 1.954179955 0.008054288 0.087599702 5.42E-05 4.266057492 0.557261444 GADDDRPSWR ddPTM_HeLa_Curcumin_4h_R1 1 GADDDRPSWR 10 1 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 89.029 0.017891 38901000 3841.7 3474.6 3030.1 3920.6 3941.4 4124.2 2952.9 3218.8 3866.8 3339.1 FALSE FALSE TRUE 3537.625391 3774.928941 3142.398172 3904.377596 3894.401379 3268.794431 3035.750427 4200.197302 3442.621714 3455.133476 1.023875175 1.092556617 0.909486766 1.130022218 1.127134858 0.94606893 0.878620304 1.215639665 0.99637879 1 11.75452573 -8.385011262 0.784966235 1.001986634 1.035426782 0.024913542 0.100860454 2.522871137 3.278228533 0.040152803 0.021923681 4.12E-09 8.385011262 0.033440148 GADEDDEKEWGDDEEEQPSK ddPTM_HeLa_Curcumin_4h_R1 1 GADEDDEKEWGDDEEEQPSK 20 1 A0A499FI31;Q15020-4;Q15020 A0A499FI31 SART3 Squamous cell carcinoma antigen recognized by T-cells 3 0 0 114.99 0.00012826 9647600 1528.5 1175.7 1447 1430.8 1305.7 2102.3 1168.3 1313.7 1506.5 1488.2 FALSE FALSE TRUE 1407.517612 1277.322269 1500.627093 1424.879729 1290.13038 1666.259282 1201.079354 1714.241082 1341.240719 1539.914839 0.91402302 0.829475914 0.974487066 0.925297745 0.837793329 1.082046383 0.77996479 1.113205119 0.870983697 1 10.58863485 -9.231549787 1.066354831 0.998308556 0.926597987 0 0.107630441 1.03480109 2.181911662 0.052529266 0.015964422 5.87E-10 9.231549787 -0.071710569 GADFLVTEVENGGSLGSK ddPTM_HeLa_Curcumin_4h_R1 2 GADFLVTEVENGGSLGSK 18 0 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BQ34 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 186.69 5.37E-08 11681310 4351.53 3436.51 3936.24 3753.24 4014.58 4722.89 3537.86 3908.72 3916.22 3387.34 FALSE FALSE TRUE 4007.101809 3733.546612 4082.120517 3737.710087 3966.708756 3743.309376 3637.12283 5100.470734 3486.620464 3505.049813 1.143236765 1.065190742 1.164639801 1.066378593 1.13171252 1.067976085 1.037680782 1.455177817 0.994742058 1 11.77521923 -1 0.017411093 3.12E-10 2.520341328 0.302067268 0.105650231 4070.261146 5.523264144 309.2775893 515.0362043 0.1 1 2.520341327 GADILRGS(ph)PSYTQASLGLLTPVSGTQEQTK ddPTM_HeLa_Curcumin_4h_R1 1 GADILRGSPSYTQASLGLLTPVSGTQEQTK 30 1 Q9UHF7;Q9UHF7-3;Q9UHF7-2;E5RFF3;H0YC29;E5RJ97 Q9UHF7 TRPS1 Zinc finger transcription factor Trps1 1 0 GADILRGS(0.239)PS(0.239)Y(0.207)T(0.239)QAS(0.077)LGLLTPVSGTQEQTK 71.295 0.00041377 0 744.49 535.17 613.17 692.5 626.93 680.12 677.1 277.61 805.86 772.04 TRUE FALSE FALSE 685.5628309 581.4277101 635.8946196 689.6346185 619.4542692 539.0554455 696.0976037 362.252011 717.4591742 798.8683325 0.858167489 0.727814192 0.795994276 0.863264433 0.775414726 0.674773831 0.871354609 0.453456466 0.898094398 1 9.641813931 -3.207185353 0.087544294 1.218069163 1.12E-11 0.485328368 0.102224263 47.51797023 0.49639977 1.477932586 7.451723793 0.000620604 3.207185353 -1.218069163 GADNDGS(ph)GS(ph)ESGYTTPK ddPTM_HeLa_Curcumin_4h_R1 3 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 2 0 GADNDGS(0.996)GS(0.516)ES(0.485)GY(0.001)T(0.002)T(0.001)PK;GADNDGS(0.785)GS(0.975)ES(0.228)GY(0.007)T(0.004)T(0.001)PK;GADNDGS(0.866)GS(0.969)ES(0.164)GY(0.001)TTPK ;; 127.88 0.00080993 234140000 21716 19421.8 20202.7 22014.3 21192 26701.3 21355 12310.2 24744.4 21413.3 TRUE FALSE FALSE 19997.15569 21100.53385 20951.42983 21923.21066 20939.29924 21163.14939 21954.16383 16063.52331 22030.00123 22157.41058 0.902504181 0.952301433 0.945572126 0.989430176 0.945024653 0.955127375 0.990827143 0.72497295 0.994249809 1 14.43550167 -1.00013472 0.011697957 1.737967734 8.35E-06 0.207567972 0.068751456 12957.71925 11.83462693 740.0751234 1042.787281 0.099968984 1.00013472 -1.737959388 GADNDGS(ph)GSES(ph)GYTTPK ddPTM_HeLa_Curcumin_4h_R1 1 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 2 0 GADNDGS(0.876)GS(0.256)ES(0.782)GY(0.008)T(0.061)T(0.016)PK 89.353 0.010989 139180000 5685.2 4955.4 5327.9 5636 5423.8 7035.9 5746.6 3077 6027.4 5540.9 TRUE FALSE FALSE 5235.210421 5383.722695 5525.356661 5612.679725 5359.124727 5576.575029 5907.83413 4015.163135 5366.2093 5733.445863 0.913100175 0.93900297 0.963706084 0.978936552 0.934712711 0.972639345 1.030415961 0.700305406 0.935948368 1 12.48518676 -4.252006364 24.93934846 0.961384028 0.700305264 0.850946722 0.03299598 406.8221229 1075548.447 0.005377504 0.092330632 5.60E-05 4.252006364 -0.261078764 GADNDGS(ph)GSESGY(ph)TTPKK ddPTM_HeLa_Curcumin_4h_R1 1 GADNDGSGSESGYTTPKK 18 1 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 2 0 GADNDGS(0.671)GS(0.294)ES(0.041)GY(0.563)T(0.109)T(0.322)PKK 62.792 0.011295 16537000 3183.7 2801.2 3020.4 2890.9 3348 3165.2 3195.5 2678 3355.7 3365.9 TRUE FALSE FALSE 2931.706786 3043.323246 3132.338681 2878.938222 3308.077287 2508.701841 3285.15713 3494.509872 2987.588106 3482.864774 0.841751539 0.873798853 0.899356962 0.826600631 0.949815023 0.720298376 0.943234189 1.00334354 0.857796182 1 11.76605874 -9.382972749 1.054085492 1.001521186 0.876756469 0 0.085580969 0.547513798 1.067153822 0.051635396 0.012632084 4.14E-10 9.382972749 -0.124764717 GADNDGS(ph)GSESGYTTPK ddPTM_HeLa_Curcumin_4h_R1 2 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 GADNDGS(0.972)GS(0.028)ESGYTTPK;GADNDGS(0.909)GS(0.091)ESGYTTPK ; 255.22 1.58E-40 477385000 5399.1 4828.9 4279.1 5337 4902.5 5577.1 3939.7 3065.7 5765.4 5476.6 TRUE FALSE FALSE 4971.755538 5246.288599 4437.68721 5314.916908 4844.040889 4420.346593 4050.237379 4000.417817 5132.950044 5666.911442 0.877330727 0.925775646 0.783087446 0.937886001 0.854793822 0.78002747 0.7147169 0.705925592 0.905775588 1 12.46834694 -1.511135381 0.14456239 1.026583059 3.87E-17 0.68626256 0.052621018 21.86560522 0.236989948 0.126463819 4.568602771 0.03082227 1.511135381 -1.026583059 GADNDGSGS(ph)ESGYTTPK ddPTM_HeLa_Curcumin_4h_R1 2 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 GADNDGS(0.008)GS(0.972)ES(0.02)GYTTPK;GADNDGS(0.008)GS(0.966)ES(0.026)GYTTPK ; 214.46 2.06E-15 499454000 14022.6 11305.5 12589.7 12383.1 12163.1 13483.6 11319.7 7060.2 14294.2 12014 TRUE FALSE FALSE 12912.69641 12282.69704 13056.28536 12331.86201 12018.06298 10686.94937 11637.30032 9212.822479 12726.16202 12431.48561 1.038709035 0.988031313 1.05025946 0.991986188 0.966743908 0.85966792 0.936115014 0.741087813 1.023704039 1 13.60171109 -3.085905895 0.523678803 1.02004245 2.74E-11 0.829921576 0.036981691 3.261748713 0.241674869 0.006954238 2.700260039 0.000820529 3.085905895 -1.02004245 GADNDGSGS(ph)ESGYTTPKK ddPTM_HeLa_Curcumin_4h_R1 1 GADNDGSGSESGYTTPKK 18 1 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 GADNDGS(0.075)GS(0.904)ES(0.021)GYTTPKK 103.24 0.00052847 18523000 1258.3 1154.5 1253.7 1382.4 1110.7 1184.4 1310.7 899.48 1590.8 1840.9 TRUE FALSE FALSE 1158.704227 1254.289836 1300.163225 1376.679995 1097.455628 938.7420891 1347.474714 1173.727311 1416.29322 1904.871138 0.608284836 0.658464402 0.682546551 0.722715552 0.576131165 0.492811335 0.707383658 0.616171503 0.743511302 1 10.89547769 -9.344097097 0.6170558 1.062903953 0.625861669 0.369552019 0.101842874 0.379314416 0.201200517 0.094538196 0.014894853 4.53E-10 9.344097097 -0.437042284 TLSPT(ph)PASATAPTSQGIPT(ph)SDEESTPK ddPTM_HeLa_Curcumin_4h_R1 1 TLSPTPASATAPTSQGIPTSDEESTPK 27 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 2 0 T(0.251)LS(0.291)PT(0.457)PAS(0.001)ATAPTSQGIPT(0.504)S(0.434)DEES(0.058)T(0.003)PK 94.869 6.39E-06 4792500 1896.1 1541.1 1558 1445.9 1876.5 1821 934.14 414.64 2026.4 1461.3 TRUE FALSE FALSE 1746.021684 1674.305817 1615.740851 1439.917249 1854.123963 1443.304073 960.3494543 541.0618272 1804.10899 1512.080066 1.1547151 1.107286482 1.06855509 0.952275796 1.22620753 0.954515641 0.635118124 0.357826176 1.193130595 1 10.56231882 -4.628863842 2.085992367 1.077490071 0.353558818 0.897689694 0.082559332 0.08338725 0.626625782 0.011743935 0.085476464 2.35E-05 4.628863842 -0.723931253 down GADNDGSGSES(ph)GYTT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 2 0 GADNDGS(0.009)GS(0.195)ES(0.795)GY(0.006)T(0.309)T(0.685)PK;GADNDGS(0.013)GS(0.224)ES(0.755)GY(0.006)T(0.288)T(0.713)PK;GADNDGS(0.001)GS(0.186)ES(0.81)GYT(0.023)T(0.979)PK ;; 144.25 0.0013354 207065000 18415.1 15018.6 16155.1 16083.2 16222 21582.2 17880.6 10662 18197.9 14724.9 TRUE FALSE FALSE 16957.5254 16316.74086 16753.82222 16016.65198 16028.56324 17105.80844 18382.28151 13912.79472 16201.6359 15236.58918 1.112947603 1.070891961 1.09957826 1.051196681 1.051978435 1.122679639 1.206456465 0.913117401 1.063337451 1 13.89525236 -9.415916692 1.084184286 0.998861563 1.085524082 0.028973973 0.072642876 0.707815464 1.45668283 0.047560788 0.011397358 3.84E-10 9.415916692 0.086662518 GADNDGSGSES(ph)GYTTPK ddPTM_HeLa_Curcumin_4h_R1 1 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 GADNDGSGS(0.012)ES(0.987)GYTTPK 170 6.80E-05 11862000 3405.6 2639 2958 2752.8 3320.4 3128.5 2681.7 1598.3 2884.2 2873.8 TRUE FALSE FALSE 3136.043166 2867.103401 3067.626082 2741.409643 3280.806399 2479.613835 2756.941285 2085.614312 2567.810476 2973.664336 1.054605635 0.96416511 1.031597966 0.92189613 1.103287402 0.833858013 0.927119195 0.701361713 0.863517259 1 11.53802609 -3.41883494 0.661771974 1.021174472 5.97E-15 0.477192848 0.081461207 3.142035617 0.427606142 0.009899279 3.143094752 0.000381211 3.41883494 -1.021174472 GADNDGSGSESGYT(ph)TPKK ddPTM_HeLa_Curcumin_4h_R1 3 GADNDGSGSESGYTTPKK 18 1 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 GADNDGSGSES(0.008)GY(0.01)T(0.491)T(0.491)PKK;GADNDGSGS(0.001)ES(0.005)GY(0.012)T(0.491)T(0.491)PKK;GADNDGS(0.11)GS(0.038)ES(0.018)GY(0.011)T(0.722)T(0.1)PKK ;; 101 0.00055113 14060700 6806.4 5355.5 5580.5 5909.2 6100.6 7343.4 5734.9 8035 7562.6 6784.4 TRUE FALSE FALSE 6267.666258 5818.405556 5787.318239 5884.749296 6027.854329 5820.296063 5895.805859 10484.83451 6733.001701 7020.157395 0.892809934 0.828814118 0.824385824 0.838264581 0.858649456 0.829083414 0.839839555 1.493532683 0.959095548 1 12.77728766 -4.257566594 24.98295017 0.905114781 1.493532912 0.891185113 0.064091427 119.2837924 769455.7799 0.011683006 0.118277645 5.53E-05 4.257566594 0.588418131 GADNDGSGSESGYTT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 GADNDGSGSESGYT(0.11)T(0.889)PK;GADNDGSGSESGY(0.015)T(0.262)T(0.722)PK ; 172.42 0.00013427 257930000 7731.9 5882.7 6386.5 6879.8 6654.5 8073.5 5814 9546.1 7925.7 6007.6 TRUE FALSE FALSE 7119.911956 6391.174375 6623.189308 6851.333211 6575.149434 6398.965093 5977.125192 12456.66195 7056.270539 6216.363653 1.145349975 1.028121058 1.065444314 1.102144854 1.057716344 1.029374318 0.961514726 2.003850264 1.135112251 1 12.60185519 -4.257778836 24.99985999 1.060534116 2.003850622 0.964043138 0.054781323 51.1048005 349007.6557 0.008578012 0.084964817 5.52E-05 4.257778836 0.943316505 GADNDGSGSESGYTT(ph)PKK ddPTM_HeLa_Curcumin_4h_R1 1 GADNDGSGSESGYTTPKK 18 1 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 GADNDGS(0.002)GS(0.004)ES(0.033)GY(0.01)T(0.246)T(0.706)PKK 73.672 0.0058181 17375000 4465.1 3782.1 3832.4 4151.4 3900.1 5045.5 4549.8 5339 4885.7 4092.3 TRUE FALSE FALSE 4111.682623 4109.007871 3974.432115 4134.222607 3853.593855 3999.006425 4677.455143 6966.836522 4349.750933 4234.50712 0.970994382 0.970362726 0.938581989 0.976317311 0.91004543 0.944385335 1.104604387 1.645253231 1.027215402 1 12.04797834 -4.26580944 2.753111719 0.973377797 1.769138875 0.975751284 0.03196932 0.04446055 0.45459633 0.004443856 0.07944727 5.42E-05 4.26580944 0.795761079 GADS(ph)GEEKEEGINR ddPTM_HeLa_Curcumin_4h_R1 2 GADSGEEKEEGINR 14 1 Q9BVG4 Q9BVG4 PBDC1 Protein PBDC1 1 0 GADS(1)GEEKEEGINR;GADS(1)GEEKEEGINR ; 214.89 8.37E-13 83076000 6112.3 5464.2 5926.1 6394.9 7707.4 7245.7 5782.1 6074.4 5554 5833.5 TRUE FALSE FALSE 5628.505005 5936.5011 6145.726479 6368.439598 7615.494289 5742.860144 5944.330164 7926.456597 4944.740095 6036.213691 0.932456221 0.983480938 1.018142629 1.055038792 1.261634309 0.951401067 0.984777953 1.313150429 0.819179099 1 12.55942816 -6.343107826 2.304877597 0.968939365 1.107870152 0.339305302 0.11489598 0.302990156 3.146546918 0.016127657 0.026714725 4.54E-07 6.343107826 0.138930786 GADS(ph)GEEKEEGINREDK ddPTM_HeLa_Curcumin_4h_R1 1 GADSGEEKEEGINREDK 17 2 Q9BVG4 Q9BVG4 PBDC1 Protein PBDC1 1 0 GADS(1)GEEKEEGINREDK 79.676 0.006926 60115000 1928.6 1760 2271.4 1749.5 2033.8 2225.9 1782.6 1731.8 1597.4 1435 TRUE FALSE FALSE 1775.949275 1912.126558 2355.580082 1742.261033 2009.548263 1764.223249 1832.614958 2259.817848 1422.169216 1484.866143 1.196033247 1.287743388 1.58639221 1.173345517 1.353353144 1.188136222 1.234195397 1.521900043 0.957776041 1 10.53611717 -8.067350589 0.812544138 1.028640163 1.32812743 0.519668451 0.131490721 0.335700111 0.48074738 0.042699612 0.030181927 8.56E-09 8.067350589 0.299487267 SEEPAGQILS(ph)HLSSELK ddPTM_HeLa_Curcumin_4h_R1 2 SEEPAGQILSHLSSELK 17 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 SEEPAGQILS(0.968)HLS(0.03)S(0.002)ELK;SEEPAGQILS(0.671)HLS(0.249)S(0.08)ELK ; 114.75 0.0004118 7379700 4326.1 3402 3022.8 3101.3 4314 4160.5 3768.7 6729.3 3308.9 3351.8 TRUE FALSE FALSE 3983.68462 3696.053721 3134.827627 3088.467642 4262.558368 3297.565402 3874.439579 8781.032592 2945.921948 3468.274801 1.148606973 1.065674992 0.903857914 0.890491042 1.229014024 0.950779737 1.117108592 2.5318157 0.849391158 1 11.7600025 -4.261950293 5.257386698 1.050860321 2.593878075 0.935440717 0.119199547 0.023985707 2.29217478 0.014515246 0.133183627 5.47E-05 4.261950293 1.543017754 up GAEAANVTGPGGVPVQGSK ddPTM_HeLa_Curcumin_4h_R1 2 GAEAANVTGPGGVPVQGSK 19 0 H0Y449;P67809 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 0 ; ; 326.09 1.98E-178 8867800 7540.3 7030.7 6759.8 6862.6 7699.3 8199.7 6710.9 6269 6828.6 5867.2 FALSE FALSE TRUE 6943.477299 7638.40238 7010.324135 6834.20438 7607.490876 6498.98979 6899.189793 8180.389241 6079.519664 6071.084763 1.143696319 1.25816105 1.15470701 1.125697408 1.253069455 1.070482466 1.136401494 1.347434529 1.001389356 1 12.5677386 -8.711003639 0.594425617 0.992427327 1.187107454 0.486380441 0.076196847 0.584385813 0.392516011 0.056466979 0.018636597 1.95E-09 8.711003639 0.194680128 GAEAFGDS(ph)EEDGEDVFEVEK ddPTM_HeLa_Curcumin_4h_R1 2 GAEAFGDSEEDGEDVFEVEK 20 0 Q99549-2;Q99549 Q99549-2 MPHOSPH8 M-phase phosphoprotein 8 1 0 GAEAFGDS(1)EEDGEDVFEVEK;GAEAFGDS(1)EEDGEDVFEVEK ; 188.32 1.53E-09 7103200 6342.9 3981.7 5139.6 5758.2 5700.8 7281.1 4947 3812.8 6282 5804.5 TRUE FALSE FALSE 5840.852772 4325.860406 5330.078097 5734.374094 5632.821683 5770.917785 5085.799506 4975.305168 5592.880317 6006.205943 0.972469614 0.720231781 0.887428461 0.954741504 0.93783359 0.960825826 0.84675743 0.828360735 0.931183574 1 12.55223823 -7.491888134 24.86579866 0.987854312 0.881743789 0.253035834 0.069483833 302.7416685 242911.9234 0.012032022 0.013150337 3.22E-08 7.491888134 -0.106110522 GAEDDELEEEADWIYR ddPTM_HeLa_Curcumin_4h_R1 4 GAEDDELEEEADWIYR 16 0 Q7KZ85;Q7KZ85-3 Q7KZ85 SUPT6H Transcription elongation factor SPT6 0 0 ;;; ;;; 213.99 3.72E-14 33905700 4514.39 3655.84 4022.49 4056.41 4735.94 5477.66 4502.08 3992.73 4719.13 3745.44 FALSE FALSE TRUE 4157.071268 3971.834519 4171.567018 4039.62565 4679.467009 4341.53157 4628.396248 5210.094997 4201.453246 3875.593761 1.072628228 1.02483252 1.076368493 1.042324325 1.207419378 1.120223593 1.194241846 1.344334654 1.084079887 1 11.92020164 -1 0.330070405 1.022758312 4.165623156 0.79881145 0.044470238 14.01423414 0.177887983 0.012981564 27.24085654 0.1 1 3.142864844 GAEETSWS(ph)GEER ddPTM_HeLa_Curcumin_4h_R1 2 GAEETSWSGEER 12 0 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 1 0 GAEETSWS(1)GEER;GAEETS(0.001)WS(0.999)GEER ; 185.57 3.92E-05 297260000 3286.1 2450.5 2664.5 2957.2 2380.2 3223.2 2617.8 1587.89 3268.5 2846.2 TRUE FALSE FALSE 3026.001718 2662.310301 2763.248714 2944.96389 2351.81767 2554.671987 2691.248423 2072.030351 2909.953727 2945.105238 1.027468112 0.903977986 0.938251265 0.999952006 0.798551318 0.867429779 0.913803822 0.70355053 0.98806443 1 11.52410347 -2.257649392 0.268162166 1.023453485 3.03E-11 0.618982098 0.059724784 10.97568267 0.252130386 0.029056908 4.574728972 0.005525233 2.257649392 -1.023453485 GAEQLAEGGR ddPTM_HeLa_Curcumin_4h_R1 2 GAEQLAEGGR 10 0 Q08J23-2;Q08J23;Q08J23-3 Q08J23-2 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 0 0 ; ; 151.22 2.84E-06 7613500 3269 2266.7 2389.6 2983.9 2411.9 3125.3 2821.1 2154.7 2978.2 2997.6 FALSE FALSE TRUE 3010.255201 2462.623448 2478.160678 2971.553412 2383.139668 2477.077551 2900.252473 2811.658111 2651.498911 3101.766377 0.970497076 0.793942273 0.798951429 0.958019738 0.768316945 0.798602232 0.935032533 0.906469982 0.854835145 1 11.59887431 -7.367488457 5.902029836 0.987002301 0.851643462 0.169533322 0.074084388 0.138189506 6.531375398 0.010569211 0.012037499 4.29E-08 7.367488457 -0.13535884 DS(ph)GRLSPDLSVCGQPR ddPTM_HeLa_Curcumin_4h_R1 1 DSGRLSPDLSVCGQPR 16 1 Q8TF76-2;Q8TF76 Q8TF76-2 GSG2 Serine/threonine-protein kinase haspin 1 0 DS(0.55)GRLS(0.45)PDLSVCGQPR 67.644 0.012394 28066000 1917.5 1291 1351.5 1589.8 1689.5 1861.8 998.9 529.01 1809.7 1511.8 TRUE FALSE FALSE 1765.727852 1402.588287 1401.587779 1583.221829 1669.353816 1475.641693 1026.926446 690.3027137 1611.180438 1564.334937 1.128740278 0.896603569 0.895963994 1.012073432 1.067133244 0.943302906 0.656462002 0.44127552 1.029945953 1 10.61133372 -4.624376142 1.909840942 1.034190985 0.420303346 0.86986724 0.071316292 0.120364191 0.725873155 0.012491121 0.101094659 2.37E-05 4.624376142 -0.613887639 down GAGAGHPGAGGAQPPDS(ph)PAGVR ddPTM_HeLa_Curcumin_4h_R1 2 GAGAGHPGAGGAQPPDSPAGVR 22 0 A0A3B3ITC2;Q13884-2;Q13884 A0A3B3ITC2 SNTB1 Beta-1-syntrophin 1 0 GAGAGHPGAGGAQPPDS(1)PAGVR;GAGAGHPGAGGAQPPDS(1)PAGVR ; 165.34 7.87E-09 11583600 6234.1 5537.4 5305.6 5699.4 6196.3 7903.3 5125.3 2381.22 6231.8 5413.9 TRUE FALSE FALSE 5740.664407 6016.028182 5502.230203 5675.817393 6122.413169 6264.066491 5269.102124 3107.243016 5548.187131 5602.032622 1.024746694 1.073900955 0.982184606 1.013171071 1.092891381 1.118177439 0.940569697 0.554663499 0.990388223 1 12.45173467 -4.284898043 3.422084561 1.026033514 0.506484562 0.912187877 0.044619963 0.057472475 1.145768286 0.006318217 0.074838736 5.19E-05 4.284898043 -0.519548951 MRRNS(ph)S(ph)LS(ph)FQMER ddPTM_HeLa_Curcumin_4h_R1 1 MRRNSSLSFQMER 13 2 F8WDW6;Q9ULM2 F8WDW6 ZNF490 Zinc finger protein 490 3 0 MRRNS(1)S(1)LS(1)FQMER 84.169 0.0082424 16541000 1758.3 1302.3 1573.5 1705.7 1379.4 1388.8 778.39 242.62 1699 1431.3 TRUE FALSE FALSE 1619.1287 1414.865009 1631.815294 1698.642265 1362.951556 1100.747225 800.2295285 316.5937211 1512.623951 1481.037568 1.093239452 0.955320134 1.10180547 1.146927196 0.920268051 0.743227078 0.540316833 0.213764815 1.021327199 1 10.53239252 -4.62223963 1.085871174 1.049398601 0.072102166 0.951116946 0.061951651 0.158264279 0.218708541 0.010194015 0.152437716 2.39E-05 4.62223963 -0.977296436 down GAGATSGS(ph)PPAGR ddPTM_HeLa_Curcumin_4h_R1 1 GAGATSGSPPAGR 13 0 B4DEE8;P16455 B4DEE8 MGMT Methylated-DNA--protein-cysteine methyltransferase 1 0 GAGATS(0.001)GS(0.998)PPAGR 122.52 0.0022743 38014000 12689 11483 11468 11822 14829 15271 12657 4069.5 11274 9954.4 TRUE FALSE FALSE 11684.65226 12475.53935 11893.01417 11773.0837 14652.17386 12103.62246 13012.12136 5310.271816 10037.27041 10300.31466 1.134397603 1.211180412 1.154626297 1.142982917 1.422497695 1.175073079 1.263274161 0.515544621 0.974462503 1 13.33040079 -4.253487831 24.70550243 1.12724035 0.515544269 0.70193385 0.12473823 406.446134 1262795.637 0.018897374 0.273388598 5.58E-05 4.253487831 -0.611696081 KKPAPLPPSS(ph)SPGPPSQDSR ddPTM_HeLa_Curcumin_4h_R1 2 KKPAPLPPSSSPGPPSQDSR 20 2 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 0 KKPAPLPPS(0.134)S(0.429)S(0.429)PGPPS(0.007)QDS(0.002)R;KKPAPLPPS(0.002)S(0.499)S(0.499)PGPPSQDSR ; 66.853 0.002277 64513000 9081.8 7841.4 7688.6 7923.8 6302.2 7092.6 4027.6 1962.4 9582.6 8601 TRUE FALSE FALSE 8362.965947 8519.175675 7973.54628 7891.013415 6227.050381 5621.51481 4140.603616 2560.726726 8531.412754 8899.88411 0.939671331 0.957223214 0.895915742 0.886642266 0.699677693 0.631639102 0.465242419 0.287725851 0.958598185 1 13.11957083 -4.619465251 0.56617697 0.979099186 4.55E-18 0.98689472 0.026386563 0.194622191 0.053792423 0.00528977 0.11510847 2.40E-05 4.619465251 -0.979099186 down GAGDGS(ph)DEEVDGK ddPTM_HeLa_Curcumin_4h_R1 4 GAGDGSDEEVDGK 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 1 0 GAGDGS(1)DEEVDGK;GAGDGS(1)DEEVDGK;GAGDGS(1)DEEVDGK;GAGDGS(1)DEEVDGK ;;; 217.19 1.47E-13 801368000 12961 11897.1 13463.2 13284.6 14807.5 14350.2 12626.7 10359.7 11396.9 10456.4 TRUE FALSE FALSE 11935.12317 12925.43231 13962.15804 13229.63185 14630.93023 11373.80676 12980.97122 13518.32484 10146.68858 10819.75912 1.103085849 1.194613685 1.290431504 1.22272887 1.352241771 1.051207022 1.199746785 1.249410887 0.937792466 1 13.40138076 -7.614965043 1.15308456 1.028623264 1.225252421 0.597780825 0.079901985 0.227024762 0.61823028 0.017180101 0.017256496 2.43E-08 7.614965043 0.196629157 GAGDGS(ph)DEEVDGKADGAEAK ddPTM_HeLa_Curcumin_4h_R1 2 GAGDGSDEEVDGKADGAEAK 20 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 0 GAGDGS(1)DEEVDGKADGAEAK;GAGDGS(1)DEEVDGKADGAEAK ; 106.47 0.00014004 49559000 3509.8 3282.4 3652.5 3998 4125.3 3858.6 3560.1 3068.2 3163.2 2722 TRUE FALSE FALSE 3231.995626 3566.11603 3787.864863 3981.457335 4076.108492 3058.282865 3659.986824 4003.680056 2816.204874 2816.589297 1.147485588 1.266111475 1.344841034 1.413573977 1.447178861 1.085810724 1.2994393 1.421463917 0.999863515 1 11.4597335 -7.57365728 0.976682266 1.037128557 1.332872809 0.636906091 0.098777649 0.234537083 0.460633378 0.024913689 0.025115038 2.67E-08 7.57365728 0.295744252 GAGDGS(ph)DEEVDGKADGAEAKPAE ddPTM_HeLa_Curcumin_4h_R1 6 GAGDGSDEEVDGKADGAEAKPAE 23 2 P35579;P35579-2 P35579 MYH9 Myosin-9 1 0 GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE;GAGDGS(1)DEEVDGKADGAEAKPAE ;;;;; 70.718 0.0011773 6957140000 18606.3 17120.4 15731.1 18158.2 17046.6 18735.4 15073.9 14154.7 20649.3 16379.7 TRUE FALSE FALSE 17133.59172 18600.21109 16314.1084 18083.06618 16843.33043 14849.46685 15496.83306 18470.40287 18384.12345 16948.89336 1.01089737 1.097429236 0.962547115 1.06691722 0.993771692 0.876131942 0.914327133 1.089770434 1.084679871 1 14.04890346 -5.509987469 24.44964108 1.013949974 0.952076605 0.166381008 0.066162991 594.0832247 1126738.097 0.00837892 0.017959819 3.09E-06 5.509987469 -0.061873369 AELPGSS(ph)SPLLAQPR ddPTM_HeLa_Curcumin_4h_R1 1 AELPGSSSPLLAQPR 15 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 0 AELPGS(0.029)S(0.485)S(0.485)PLLAQPR 84.31 0.012316 24432000 2409.9 1985.8 2163.6 2309 2311 2139.7 1213.2 458.17 2565.8 1913.7 TRUE FALSE FALSE 2219.153872 2157.443703 2243.784919 2299.44597 2283.442834 1695.902101 1247.239127 597.8639238 2284.338159 1980.200933 1.120671057 1.089507468 1.133109718 1.161218507 1.153136935 0.856429301 0.629854833 0.301920837 1.153589074 1 10.95143111 -4.618519393 1.585382462 1.079879539 0.255801587 0.945883123 0.063376837 0.105720716 0.394440713 0.010766193 0.108995552 2.41E-05 4.618519393 -0.824077952 down KASS(ph)PSPLTIGTPESQR ddPTM_HeLa_Curcumin_4h_R1 1 KASSPSPLTIGTPESQR 17 1 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 0 KAS(0.03)S(0.484)PS(0.484)PLT(0.002)IGTPESQR 120.15 0.000299 65743000 1807.4 1094.9 1386.6 1596.1 1493 1133.4 721.41 389.02 1513.4 1591.4 TRUE FALSE FALSE 1664.342383 1189.538277 1437.988616 1589.495761 1475.19695 898.3200639 741.650823 507.6304072 1347.383806 1646.701032 1.010713148 0.722376591 0.873254214 0.965260682 0.895849897 0.545527116 0.450385837 0.308271142 0.818232199 1 10.68536293 -4.615741958 0.63135282 0.98978324 6.47E-12 0.779948616 0.109469993 0.604523376 0.214121483 0.018322536 0.394568334 2.42E-05 4.615741958 -0.98978324 down GAGPQLLEELDNAPGS(ph)DAAELELAPARTPPDSVKDASAAEPAAAER ddPTM_HeLa_Curcumin_4h_R1 1 GAGPQLLEELDNAPGSDAAELELAPARTPPDSVKDASAAEPAAAER 46 2 Q9UHR6 Q9UHR6 ZNHIT2 Zinc finger HIT domain-containing protein 2 1 0 GAGPQLLEELDNAPGS(0.542)DAAELELAPART(0.444)PPDS(0.013)VKDAS(0.001)AAEPAAAER 65.938 2.59E-07 6822300 1999 1435.2 1242.8 1891.1 1520.2 2578.9 1644.9 1324.1 1997.7 1635.6 TRUE FALSE FALSE 1840.777041 1559.252293 1288.859261 1883.275129 1502.072608 2044.00707 1691.051467 1727.811995 1778.557308 1692.436978 1.087648795 0.921305971 0.761540476 1.112759384 0.887520556 1.207730093 0.999181351 1.020901822 1.050885398 1 10.7248864 -1.99440568 8.012202378 1.01875869 1.171595489 0 0.119977388 0 0 0.015230143 0 0.010129647 1.99440568 0.1528368 GAGPQLLEELDNAPGSDAAELELAPART(ph)PPDSVKDASAAEPAAAER ddPTM_HeLa_Curcumin_4h_R1 1 GAGPQLLEELDNAPGSDAAELELAPARTPPDSVKDASAAEPAAAER 46 2 Q9UHR6 Q9UHR6 ZNHIT2 Zinc finger HIT domain-containing protein 2 1 0 GAGPQLLEELDNAPGS(0.195)DAAELELAPART(0.646)PPDS(0.143)VKDAS(0.017)AAEPAAAER 61.555 7.76E-06 25232000 3679 2740.8 3266.1 2941.1 3061.5 4987.1 3470.9 2171.5 3460.4 3228.3 TRUE FALSE FALSE 3387.803268 2977.702539 3387.144539 2928.930507 3024.993612 3952.719244 3568.284113 2833.580354 3080.802777 3340.483185 1.01416564 0.891398751 1.013968445 0.876798459 0.905555707 1.183277695 1.068194005 0.848254638 0.922262621 1 11.70584108 -4.243020008 23.35739914 0.999059327 0.848254313 0.162836867 0.089636245 1940.200577 2460249.936 0.01177326 0.47531217 5.71E-05 4.243020008 -0.150805014 GAGSIAGASAS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 GAGSIAGASASPK 13 0 P15924-2;P15924-3;P15924 P15924-2 DSP Desmoplakin 1 0 GAGS(0.003)IAGAS(0.006)AS(0.992)PK;GAGSIAGASAS(1)PK ; 143.94 0.00081996 11684300 3963.9 3854.6 4052.3 4417.4 4568.1 4569.4 3112.5 2053.41 4061 4012.6 TRUE FALSE FALSE 3650.153132 4187.774448 4202.481803 4399.121969 4513.628391 3621.654932 3199.828373 2679.485256 3615.51846 4152.037551 0.879123343 1.008607075 1.012149276 1.059509196 1.087087565 0.872259677 0.770664603 0.64534225 0.870781734 1 12.01960378 -4.709245953 2.216859165 0.969245585 0.661604 0.723607056 0.06939471 0.153147643 1.390642192 0.011063012 0.064341654 1.95E-05 4.709245953 -0.307641585 GAGTDDHTLIR ddPTM_HeLa_Curcumin_4h_R1 2 GAGTDDHTLIR 11 0 P08758;D6RBE9;D6RBL5 P08758 ANXA5 Annexin A5;Annexin 0 0 ; ; 131.83 0.00020841 18586300 12816.8 9316 10570.4 10854.3 10685.2 11611.5 10499.5 9785.5 10912.2 10493.1 FALSE FALSE TRUE 11802.33676 10121.23353 10962.14832 10809.38778 10557.78597 9203.144011 10794.08771 12769.0539 9715.158961 10857.73444 1.086998104 0.932168085 1.009616544 0.995547261 0.972374672 0.847611816 0.99413812 1.17603299 0.894768518 1 13.40643548 -7.265527664 24.97272542 1.041082437 0.984682957 0 0.091839826 650.1825114 3971536.944 0.013887938 0.016186606 5.43E-08 7.265527664 -0.056399479 GAGTGGLGLAVEGPSEAK ddPTM_HeLa_Curcumin_4h_R1 2 GAGTGGLGLAVEGPSEAK 18 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 380.78 4.82E-291 19927300 8628.3 7015.5 7693.6 7618.9 7378.5 9648.3 6936.3 6883 8581.2 7850.2 FALSE FALSE TRUE 7945.36095 7621.88856 7978.731584 7587.375011 7290.516207 7647.133821 7130.91391 8981.595015 7639.863829 8122.993866 0.978132088 0.938310269 0.982240257 0.934061399 0.897515907 0.941418146 0.877867696 1.105700086 0.940523156 1 12.98779584 -7.580096798 0.969317801 0.994736408 0.946906172 0 0.060887839 0.765850923 1.484166557 0.013165345 0.013212927 2.63E-08 7.580096798 -0.047830236 GAGTGGLGLTVEGPCEAK ddPTM_HeLa_Curcumin_4h_R1 1 GAGTGGLGLTVEGPCEAK 18 0 Q14315-2;Q14315;O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 Q14315-2;O75369-8 FLNC;FLNB Filamin-C;Filamin-B 0 0 205.26 1.45E-18 2321900 1212.7 867.03 1098 847.1 1005.8 1527.3 1285.8 1511 1280.2 1135.8 FALSE FALSE TRUE 1116.713515 941.9722098 1138.692846 843.5949247 993.8064919 1210.520764 1321.876087 1971.696944 1139.765263 1175.268965 0.950176979 0.801495009 0.968878512 0.717788821 0.845599196 1.029994665 1.124743464 1.677655926 0.969790998 1 10.19877525 -4.159825606 1.689566936 0.936079253 2.076149516 0.862098432 0.092628585 0.373425771 0.83930284 0.014659262 0.74278514 6.92E-05 4.159825606 1.140070262 GAGTNEDALIEILTTR ddPTM_HeLa_Curcumin_4h_R1 2 GAGTNEDALIEILTTR 16 0 P12429;D6RA82;D6RFG5;D6RCA8 P12429 ANXA3 Annexin A3;Annexin 0 0 ; ; 222.55 8.73E-15 4678000 1015.68 1031.15 1091.32 1249.56 1142.64 1689.25 1115.14 1107.76 1032.65 1212.71 FALSE FALSE TRUE 935.2878563 1120.278011 1131.765279 1244.389652 1129.014764 1338.880508 1146.427827 1445.510925 919.3708786 1254.851582 0.745337432 0.89275738 0.901911664 0.991662814 0.89971976 1.066963239 0.913596351 1.151937763 0.732653082 1 10.29330102 -3.250470343 0.521644742 0.883491068 1.663805073 0.427870303 0.093598624 9.319417608 0.789835044 0.020847651 5.645434739 0.000561733 3.250470343 0.780314005 GAIILAK ddPTM_HeLa_Curcumin_4h_R1 2 GAIILAK 7 0 P15880;H0YEN5;E9PMM9;I3L404;E9PPT0;E9PM36 P15880 RPS2 40S ribosomal protein S2 0 0 ; ; 126.05 0.0089149 6214300 7429.3 6520.9 7179.5 6973.5 7468.1 8716.8 7190.4 6538 8056.5 6621.4 FALSE FALSE TRUE 6841.263066 7084.537539 7445.578586 6944.645505 7379.047785 6908.837421 7392.143272 8531.406103 7172.722106 6851.493157 0.998506881 1.034013663 1.086708899 1.013595919 1.07699849 1.008369601 1.078909823 1.24518932 1.046884517 1 12.74220272 -1 0.842925748 1.011224326 79.312231 0.754356216 0.034584165 198.5766151 0.53908265 0.005492939 29815.97235 0.1 1 78.30100668 GAILSEEELAAMS(ph)PTAAAVAK ddPTM_HeLa_Curcumin_4h_R1 1 GAILSEEELAAMSPTAAAVAK 21 0 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 0 GAILSEEELAAMS(0.825)PT(0.175)AAAVAK 99.891 0.00010411 13592000 4953.9 3551.4 4139.9 4267 4412.7 6766 6834 5335 5175.4 3654.1 TRUE FALSE FALSE 4561.793588 3858.367191 4293.328336 4249.344285 4360.081435 5362.655331 7025.743647 6961.616941 4607.671568 3781.079703 1.206479087 1.020440587 1.135476814 1.123844145 1.153131321 1.418286773 1.858131592 1.841171699 1.218612653 1 11.88458255 -4.956204229 1.997869735 1.098981563 1.884796976 0.942865456 0.070967769 0.059450174 0.453079129 0.011872622 0.051442962 1.11E-05 4.956204229 0.785815413 TSS(ph)KES(ph)SPIPSPTSDR ddPTM_HeLa_Curcumin_4h_R1 1 TSSKESSPIPSPTSDR 16 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 2 0 T(0.109)S(0.157)S(0.734)KES(0.579)S(0.396)PIPS(0.024)PT(0.001)SDR 138.98 0.0016073 24149000 4580.7 3609.1 3913.1 4273.3 3517.5 4832.4 4426.1 6260 4702.4 3821.9 TRUE FALSE FALSE 4218.132761 3921.054522 4058.122928 4255.618217 3475.55611 3830.105768 4550.284454 8168.645183 4186.558485 3954.710741 1.066609681 0.991489588 1.026149115 1.076088366 0.878839525 0.968492013 1.150598553 2.065548081 1.058625715 1 11.94935646 -4.261635403 3.431460416 1.018269078 2.197897191 0.970000933 0.055416626 0.03602896 0.714051737 0.007959081 0.110476776 5.47E-05 4.261635403 1.179628113 up GAK(ac)LTPEEEEILNK ddPTM_HeLa_Curcumin_4h_R1 1 GAKLTPEEEEILNK 14 1 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 1 GAK(1)LTPEEEEILNK 283.47 5.11E-94 3637000 1333 1285.7 1401.7 1190.5 1264.7 1431.6 1212.3 1183.3 1299.1 1098.6 FALSE TRUE FALSE 1227.491643 1396.830179 1453.648235 1185.574026 1249.619279 1134.670023 1246.313875 1544.082723 1156.59198 1136.776268 1.079800553 1.228764373 1.278746114 1.04292644 1.099265804 0.998147177 1.096358105 1.358299576 1.017431497 1 10.15073263 -7.819658788 1.733298302 1.024471403 1.145695456 0.228181371 0.104737195 0.381108487 2.381621818 0.022724001 0.021551277 1.51E-08 7.819658788 0.121224053 GAKEEHGGLIRS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 GAKEEHGGLIRSPR 14 2 P26368;P26368-2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 1 0 GAKEEHGGLIRS(1)PR 54.811 0.017298 293620000 10256 8249 8074.7 9149.9 8079.7 11356 8246.9 5054.6 12037 10019 TRUE FALSE FALSE 9444.226778 8962.006803 8373.955485 9112.040138 7983.354855 9000.637592 8478.285819 6595.724271 10716.57122 10367.1595 0.910975352 0.864461167 0.807738656 0.878933148 0.77006193 0.868187432 0.817802197 0.636213253 1.033703707 1 13.33973304 -1.086931069 0.098428296 1.11399179 1.47E-18 0.763248334 0.052288631 43.46238227 0.311455394 0.428641324 6.56090582 0.081859471 1.086931069 -1.11399179 GALALEEK ddPTM_HeLa_Curcumin_4h_R1 2 GALALEEK 8 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ; ; 147.52 0.00028129 15806700 11544 8442.9 10129.5 10019.5 10686.9 12569.5 9864.4 8624.5 10804.4 10447.5 FALSE FALSE TRUE 10630.28022 9172.666655 10504.90818 9978.041964 10559.4657 9962.444013 10141.16852 11254.07035 9619.184351 10810.54985 0.983324657 0.848492147 0.971727463 0.922991162 0.976774155 0.921548317 0.938080732 1.041026637 0.889796031 1 13.40015228 -7.49736926 24.62160915 0.992643276 0.943745019 0 0.056566723 253.8312006 244999.606 0.007600643 0.008194328 3.18E-08 7.49736926 -0.048898257 GALFKT(ph)PFGPT(ph)HVNR ddPTM_HeLa_Curcumin_4h_R1 1 GALFKTPFGPTHVNR 15 1 Q9H1X1;Q9H1X1-2 Q9H1X1 RSPH9 Radial spoke head protein 9 homolog 2 0 GALFKT(1)PFGPT(1)HVNR 71.558 0.016772 24397000 1038.2 747.44 1034 673.93 754.28 1027.1 878.58 730.1 1410.9 945.22 TRUE FALSE FALSE 956.0253745 812.0453831 1072.32095 671.1414562 745.2857036 814.0678822 903.2305902 952.704129 1256.1278 978.0663246 0.977464769 0.830255947 1.096368337 0.686192173 0.761999146 0.832323802 0.923486033 0.974069043 1.284297157 1 9.93378849 -7.342905344 5.74148862 0.990023331 0.869889577 0.255957187 0.141488419 0.262781202 14.41926682 0.018302276 0.020878282 4.54E-08 7.342905344 -0.120133754 GALHTVS(ph)HEDIR ddPTM_HeLa_Curcumin_4h_R1 2 GALHTVSHEDIR 12 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2;H0YD72 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 0 GALHT(0.38)VS(0.62)HEDIR;GALHT(0.26)VS(0.74)HEDIR ; 84.173 0.0097774 404240000 8982.2 8063.9 8902.2 8175 9659.7 9960.8 7520.8 5108.6 9522.9 7764.9 TRUE FALSE FALSE 8271.249392 8760.907584 9232.123363 8141.174016 9544.514386 7894.817799 7731.813407 6666.188623 8478.261695 8034.729697 1.029437169 1.090379878 1.149027249 1.013248027 1.187907341 0.982586608 0.962299131 0.829671797 1.055201857 1 12.97203377 -4.390179588 1.843778969 1.040482596 0.796804656 0.550778727 0.064121607 0.430389392 1.811537673 0.009748407 0.164543845 4.07E-05 4.390179588 -0.24367794 GALHTVS(ph)HEDIRDIR ddPTM_HeLa_Curcumin_4h_R1 2 GALHTVSHEDIRDIR 15 1 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2;H0YD72 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 0 GALHT(0.013)VS(0.987)HEDIRDIR;GALHT(0.168)VS(0.832)HEDIRDIR ; 73.833 0.0090237 39314000 3913.1 3254.9 2800.6 3594.1 2788.4 4675.7 2892 2298 5803.1 4078.3 TRUE FALSE FALSE 3603.374006 3536.239052 2904.3927 3579.228567 2755.150151 3705.907114 2973.141737 2998.649621 5166.514449 4220.020621 0.853875924 0.837967245 0.688241352 0.848154283 0.652875992 0.87817275 0.704532514 0.710577007 1.224286541 1 12.04303433 -8.107564961 0.380370674 1.024494864 0.728125792 0.623906061 0.100422797 0.53067445 0.190397229 0.064344929 0.033163753 7.81E-09 8.107564961 -0.296369072 GALLGCLCLALLCLGGADK ddPTM_HeLa_Curcumin_4h_R1 1 GALLGCLCLALLCLGGADK 19 0 J3QQ64;A0A087WWI1;D6RHI9;A0A087WZM2;O00584-2;O00584 J3QQ64 RNASET2 Ribonuclease T2 0 0 59.261 0.019086 22333000 2022.8 1834.8 1704.8 1827.4 1688.9 2817.1 1775 1803.6 2365.2 1891.1 FALSE FALSE TRUE 1862.693246 1993.391936 1767.981388 1819.838703 1668.760971 2232.801705 1824.801723 2353.509337 2105.743477 1956.815584 0.951900251 1.018691773 0.903499237 0.930000107 0.852794195 1.14103839 0.932536381 1.202724138 1.076107271 1 10.93429208 -1.827764659 1.354547183 0.969280949 199.9999999 0.382582396 0.082361974 839.4173653 2.186625801 0.010132466 518421.165 0.014867411 1.827764659 199.030719 GALPPS(ph)PALPRPSR ddPTM_HeLa_Curcumin_4h_R1 3 GALPPSPALPRPSR 14 1 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 0 GALPPS(0.999)PALPRPS(0.001)R;GALPPS(0.991)PALPRPS(0.009)R;GALPPS(1)PALPRPSR ;; 84.195 0.0066762 85389000 6444.6 5640.7 5732 6098.1 5418.8 4886.6 3439.72 4777.5 5564.8 6322.5 TRUE FALSE FALSE 5934.50311 6128.256974 5944.432962 6072.867678 5354.184349 3873.064077 3536.229286 6234.137757 4954.355362 6542.206404 0.907110345 0.936726327 0.908628159 0.928259872 0.818406516 0.592011905 0.540525484 0.952910589 0.757291204 1 12.67556156 -5.567023166 3.126124736 0.948006622 0.680564817 0.346769449 0.120656218 0.132134564 2.635947487 0.014795708 0.032786326 2.71E-06 5.567023166 -0.267441806 GALQNIIPAS(ph)TGAAK ddPTM_HeLa_Curcumin_4h_R1 2 GALQNIIPASTGAAK 15 0 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 0 GALQNIIPAS(0.915)T(0.085)GAAK;GALQNIIPAS(0.5)T(0.5)GAAK ; 212.35 1.31E-10 441220000 9481.2 6531.3 8802.2 9256.9 8326.8 11451.5 9076.9 8111.2 10021.9 7703.9 TRUE FALSE FALSE 8730.753015 7095.836469 9128.417275 9218.597401 8227.508348 9076.329815 9331.573385 10584.26754 8922.522644 7971.609952 1.095230834 0.890138443 1.145115896 1.156428558 1.032101219 1.138581776 1.17060085 1.327745287 1.119287408 1 12.96065541 -1 0.445789573 1.037487494 7.19048481 0.541893967 0.074771612 39.31182325 0.427921521 0.015492267 221.4935207 0.1 1 6.152997316 GALQNIIPASTGAAK ddPTM_HeLa_Curcumin_4h_R1 2 GALQNIIPASTGAAK 15 0 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 ; ; 247.88 1.33E-48 177693000 7136.3 5749.9 6113 6225.7 6230.2 8413.8 7023 6378.8 6886.6 6456.3 FALSE FALSE TRUE 6571.454325 6246.895735 6339.553158 6199.939703 6155.908934 6668.683037 7220.046479 8323.666756 6131.157209 6680.655944 0.983654057 0.935072213 0.948941722 0.928043557 0.921452771 0.998207825 1.080739158 1.245935553 0.917747787 1 12.70577405 -4.363560316 1.910127652 0.975064541 1.296164264 0.873743108 0.034090467 0.176392102 0.782741047 0.005172967 0.092594488 4.33E-05 4.363560316 0.321099722 GANDFMCDEMER ddPTM_HeLa_Curcumin_4h_R1 6 GANDFMCDEMER 12 0 P17987;E7EQR6;F5H282;E7ERF2;F5GZ03 P17987 TCP1 T-complex protein 1 subunit alpha 0 0 ;;;;; ;;;;; 310.77 1.36E-88 111121000 11262.2 9742.9 10462.3 8724.66 9869 11447.3 9662.7 8823.4 9600.7 9443.3 FALSE FALSE TRUE 10370.78499 10585.03286 10850.04204 8688.559669 9751.318621 9073.000942 9933.809356 11513.61404 8547.52723 9771.453972 1.061334886 1.083260781 1.110381533 0.889177772 0.99793937 0.928521075 1.016615274 1.178290772 0.874744665 1 13.25435753 GANPVEIRR ddPTM_HeLa_Curcumin_4h_R1 2 GANPVEIRR 9 1 P10809;E7EXB4;E7ESH4;P10809-2 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 ; ; 109.44 0.012049 5666600 5510.5 4482.1 4057.7 4713.5 3612.6 6189 4032.2 3600.4 5546.9 4328.5 FALSE FALSE TRUE 5074.33811 4869.512752 4208.081932 4693.996786 3569.522104 4905.331636 4145.33268 4698.145386 4938.418948 4478.915053 1.132939127 1.087208106 0.939531534 1.048020945 0.796961332 1.095205329 0.925521612 1.048947196 1.102592679 1 12.12893359 -6.766607474 24.99847517 1.066363219 0.97401241 0.264444268 0.084410369 150.8891837 729863.3933 0.013694684 0.018301748 1.71E-07 6.766607474 -0.092350809 GAPANVS(ph)SSDLTGR ddPTM_HeLa_Curcumin_4h_R1 1 GAPANVSSSDLTGR 14 0 H0Y5S9;H0Y682;P49674 H0Y5S9 CSNK1E Casein kinase I isoform epsilon 1 0 GAPANVS(0.416)S(0.416)S(0.14)DLT(0.028)GR 80.719 0.018444 17045000 803.14 680.91 508.37 567.28 599.43 1154.4 816.73 464.38 590.79 696.6 TRUE FALSE FALSE 739.5706215 739.7648263 527.2106394 564.9327457 592.2821888 914.9644272 839.6452457 605.9673243 525.9818151 720.8067981 1.026031696 1.026301123 0.731417407 0.783750579 0.8216934 1.26936154 1.164868655 0.840679258 0.729712617 1 9.493468807 KDTETENPPVENTLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 KDTETENPPVENTLSPK 17 1 Q96RS0 Q96RS0 TGS1 Trimethylguanosine synthase 1 0 KDTETENPPVENT(0.317)LS(0.683)PK 83.723 0.0034227 0 2050.9 1555.4 1534 1785.3 1872.9 2060.9 2268.3 5382.2 2004.5 2004.1 TRUE FALSE FALSE 1888.569101 1689.841845 1590.851389 1777.912902 1850.566891 1633.446109 2331.942393 7023.208003 1784.611365 2073.742326 0.91070577 0.814875515 0.767140338 0.857345139 0.892380344 0.787680363 1.124509233 3.386731281 0.860575271 1 11.01802093 -4.261612903 4.091063995 0.912794202 3.597044446 0.989325948 0.078058551 0.018833077 0.676441193 0.013070575 0.148468094 5.48E-05 4.261612903 2.684250244 up GAPLVVICQGK ddPTM_HeLa_Curcumin_4h_R1 1 GAPLVVICQGK 11 0 Q14195-2;Q14195 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 0 0 139.97 7.05E-05 1229800 464.84 382.56 379.6 652.8 471.86 491.09 453.66 498.06 530.9 470.83 FALSE FALSE TRUE 428.0474235 415.6267817 393.6683099 650.0988866 466.2333777 389.2323983 466.3884786 649.9162012 472.6615982 487.1913075 0.878602342 0.853107959 0.808036399 1.334381128 0.956982135 0.798931328 0.957300493 1.334006152 0.970176584 1 8.928344582 VS(ph)PPAPGSAPET(ph)PEDK ddPTM_HeLa_Curcumin_4h_R1 1 VSPPAPGSAPETPEDK 16 0 M0R0P8;Q13459-2;Q13459;M0R300 M0R0P8 MYO9B Unconventional myosin-IXb 2 0 VS(0.666)PPAPGS(0.334)APET(1)PEDK 114.58 0.0057697 11653000 1797.2 1450.8 1816.5 1979.2 1849.4 2026.8 1874.8 4443.9 1860 1814.8 TRUE FALSE FALSE 1654.949724 1576.200687 1883.821088 1971.010595 1827.347113 1606.418833 1927.401842 5798.824653 1655.962653 1877.864165 0.881293628 0.839358201 1.00317218 1.049602326 0.973098666 0.855449965 1.026379798 3.087989409 0.881833034 1 10.87487699 -4.261586417 5.451949497 0.94424817 3.168312995 0.989170845 0.067303471 0.010858427 1.213134283 0.009955965 0.089762879 5.48E-05 4.261586417 2.224064825 up GAPSQDDESGGIEDS(ph)PDR ddPTM_HeLa_Curcumin_4h_R1 2 GAPSQDDESGGIEDSPDR 18 0 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 GAPSQDDESGGIEDS(1)PDR;GAPSQDDESGGIEDS(1)PDR ; 293.22 1.58E-81 20697600 1953.85 1962.69 1842.83 1942.63 2122.27 2812.56 2145.2 2227.73 1883.9 1652.23 TRUE FALSE FALSE 1799.200711 2132.336178 1911.126901 1934.591912 2096.963316 2229.203352 2205.388538 2906.954622 1677.240883 1709.64487 1.052382716 1.247239246 1.117850224 1.131575303 1.226549065 1.303898483 1.289968799 1.700326585 0.981046364 1 10.73948096 -1 0.32382643 1.018037133 7.000272557 0.853052338 0.07599912 12.55347835 0.159806118 0.024080747 45.27598983 0.1 1 5.982235424 NLVSPAYCTQES(ph)REEIPGGEAR ddPTM_HeLa_Curcumin_4h_R1 1 NLVSPAYCTQESREEIPGGEAR 22 1 Q9NUQ3 Q9NUQ3 TXLNG Gamma-taxilin 1 0 NLVS(0.007)PAY(0.054)CT(0.115)QES(0.823)REEIPGGEAR 48.872 0.01493 110150000 925.98 568.74 999.03 1021.4 886.14 747.81 993.12 5254.8 595.68 592.17 TRUE FALSE FALSE 852.6877059 617.8993513 1036.054931 1017.173717 875.5733593 592.7057764 1020.984274 6856.96433 530.3353943 612.7478634 1.391580056 1.00840719 1.690834016 1.660020015 1.428929273 0.967291462 1.666238816 11.19051528 0.865503457 1 9.259149738 -4.261401637 5.275033718 1.253149835 11.60583829 0.991416694 0.276386813 0.009422457 0.912662428 0.038192681 0.35204023 5.48E-05 4.261401637 10.35268845 up GAPSS(ph)PATGVLPSPQGK ddPTM_HeLa_Curcumin_4h_R1 3 GAPSSPATGVLPSPQGK 17 0 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 1 0 GAPS(0.001)S(0.584)PAT(0.412)GVLPS(0.003)PQGK;GAPS(0.003)S(0.993)PAT(0.004)GVLPSPQGK;GAPS(0.002)S(0.986)PAT(0.013)GVLPSPQGK ;; 233.4 1.98E-22 72228000 10235.6 8440.8 9839.1 9917.4 9364.7 11570.1 10994.6 14577.1 10731.6 9835.3 TRUE FALSE FALSE 9425.441459 9170.385141 10203.7457 9876.364427 9253.032069 9170.330838 11303.07889 19021.59069 9554.370329 10177.07594 0.926144357 0.901082511 1.002620572 0.970452071 0.909203402 0.901077175 1.110641106 1.869062469 0.938812915 1 13.31303549 -4.265560537 3.014010564 0.955879392 2.012931793 0.981381308 0.03804517 0.038478771 0.513186617 0.006078266 0.096761454 5.43E-05 4.265560537 1.0570524 GAPVIVPELGKPRQS(ph)PLTYEDHGAPFAGHLPR ddPTM_HeLa_Curcumin_4h_R1 2 GAPVIVPELGKPRQSPLTYEDHGAPFAGHLPR 32 2 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 GAPVIVPELGKPRQS(0.647)PLT(0.303)Y(0.05)EDHGAPFAGHLPR;GAPVIVPELGKPRQS(0.876)PLT(0.11)Y(0.013)EDHGAPFAGHLPR ; 67.388 1.78E-05 93937000 2901.01 2310.67 2504.21 2296.94 2393.55 4175 3561 1477.75 3662.9 2406.01 TRUE FALSE FALSE 2671.391997 2510.394019 2597.018226 2287.435871 2365.00848 3309.057938 3660.912076 1928.309172 3261.089034 2489.618668 1.073012518 1.008344792 1.043138959 0.918789652 0.949948082 1.329142483 1.470471009 0.774539971 1.309874912 1 11.28170907 -5.268463502 24.9784958 1.020099291 1.219293142 0.096036863 0.19390465 567.114228 2016718.027 0.022414651 0.051121107 5.39E-06 5.268463502 0.19919385 GAPVNIS(ph)SSDLTGR ddPTM_HeLa_Curcumin_4h_R1 2 GAPVNISSSDLTGR 14 0 H7BYT1;P48730-2;P48730;J3KRM8 H7BYT1 CSNK1D Casein kinase I isoform delta 1 0 GAPVNIS(0.748)S(0.229)S(0.022)DLT(0.002)GR;GAPVNIS(0.544)S(0.34)S(0.109)DLT(0.006)GR ; 144.15 0.00066195 81622000 2955.8 2427.2 1949.65 2294.2 2089.01 3737.6 2622.6 1110.17 2780.3 2644.2 TRUE FALSE FALSE 2721.845311 2636.996353 2021.905744 2284.707208 2064.09992 2962.379629 2696.183098 1448.655722 2475.308046 2736.085753 0.994795323 0.963784249 0.738977476 0.835027632 0.754398841 1.082707158 0.985416153 0.529462836 0.904689498 1 11.41789773 -6.92047178 7.338876251 0.996612127 0.838226232 0.184705583 0.142183231 0.254180692 19.97135377 0.02171207 0.02858108 1.20E-07 6.92047178 -0.158385894 GAQASSGS(ph)PALPR ddPTM_HeLa_Curcumin_4h_R1 3 GAQASSGSPALPR 13 0 P42684-2;P42684-3;P42684-4;P42684-10;P42684-6;P42684;P42684-7;P42684-5 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 0 GAQASS(0.003)GS(0.996)PALPR;GAQAS(0.009)S(0.028)GS(0.963)PALPR;GAQAS(0.019)S(0.034)GS(0.947)PALPR ;; 139.6 0.0010108 263714000 10959.2 8162.3 10414.1 10193.5 10300.2 8943 7079.6 3639.57 10733.6 9435.2 TRUE FALSE FALSE 10091.76776 8867.812841 10800.05571 10151.322 10177.37684 7088.120992 7278.234522 4749.258138 9556.150934 9763.072498 1.033667194 0.908301443 1.106214843 1.039767143 1.042435857 0.726013352 0.745486067 0.48645118 0.978805692 1 13.25311953 -4.807928233 1.286637032 1.019559826 0.500575979 0.84652408 0.072365541 0.159298954 0.399672305 0.009958332 0.083659297 1.56E-05 4.807928233 -0.518983847 SWDSS(ph)SPVDRPEPEAAS(ph)PTTR ddPTM_HeLa_Curcumin_4h_R1 1 SWDSSSPVDRPEPEAASPTTR 21 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 2 0 S(0.004)WDS(0.084)S(0.658)S(0.255)PVDRPEPEAAS(0.744)PT(0.24)T(0.016)R 102.28 7.13E-05 93269000 2919.5 2435 2765.7 2733.9 2835.4 3034.9 1326.9 460.96 2923.2 2287 TRUE FALSE FALSE 2688.418494 2645.47055 2868.199275 2722.587846 2801.589707 2405.42753 1364.129243 601.504582 2602.532273 2366.47308 1.136044402 1.117895899 1.212014326 1.150483337 1.183867136 1.016460973 0.576439789 0.254177657 1.099751481 1 11.2085228 -4.613617585 2.292963834 1.095954626 0.255970363 0.956237246 0.061820416 0.064718497 0.603356875 0.011826339 0.080714048 2.43E-05 4.613617585 -0.839984264 down GARPPAAGPGGDEDEDEEDTAPESALDT(ph)SLDK ddPTM_HeLa_Curcumin_4h_R1 1 GARPPAAGPGGDEDEDEEDTAPESALDTSLDK 32 1 Q27J81-2;A0A0A0MQU1;Q27J81 Q27J81-2 INF2 Inverted formin-2 1 0 GARPPAAGPGGDEDEDEEDTAPES(0.004)ALDT(0.523)S(0.472)LDK 81.569 9.02E-07 15121000 897.12 983.55 994.39 849.44 1150 940.27 834.62 449.8 910.31 811.61 TRUE FALSE FALSE 826.1120054 1068.563679 1031.242968 845.9252424 1136.287001 745.247403 858.0371909 586.9419494 810.4512705 839.8133871 0.983685207 1.272382289 1.227942998 1.007277635 1.353023206 0.887396432 1.021699825 0.698895681 0.965037332 1 9.713924975 -3.901168614 1.555783364 1.050750648 0.198259862 0.367426023 0.146376788 2.746604481 2.942911644 0.021696415 4.689448511 0.000125554 3.901168614 -0.852490787 GARPPAAGPGGDEDEDEEDTAPESALDTS(ph)LDK ddPTM_HeLa_Curcumin_4h_R1 1 GARPPAAGPGGDEDEDEEDTAPESALDTSLDK 32 1 Q27J81-2;A0A0A0MQU1;Q27J81 Q27J81-2 INF2 Inverted formin-2 1 0 GARPPAAGPGGDEDEDEEDTAPES(0.002)ALDT(0.302)S(0.695)LDK 73.487 1.29E-05 12824000 528.5 520.88 397.15 350.05 588.07 602.16 413.93 421.85 444.3 515.05 TRUE FALSE FALSE 486.6686673 565.9025462 411.8687284 348.6015859 581.0576493 477.2652283 425.5437618 550.470123 395.5614016 532.9479492 0.913163599 1.061834551 0.772812296 0.654100624 1.090270917 0.895519401 0.798471525 1.032877833 0.742213948 1 9.057850828 -8.462317454 0.566640182 0.998701158 0.889367634 0 0.151207731 1.685176316 1.125499023 0.085602924 0.035367208 3.45E-09 8.462317454 -0.109333523 GAS(ph)PDMAPILEPVDR ddPTM_HeLa_Curcumin_4h_R1 5 GASPDMAPILEPVDR 15 0 E9PDC2;A0A088AWP5;Q8WUY3-4;Q8WUY3;Q8WUY3-2;Q8WUY3-3;H7BZH9 E9PDC2 PRUNE2 Protein prune homolog 2 1 0 GAS(1)PDMAPILEPVDR;GAS(1)PDMAPILEPVDR;GAS(1)PDMAPILEPVDR;GAS(1)PDMAPILEPVDR;GAS(1)PDMAPILEPVDR ;;;; 196.97 9.75E-07 84937600 10278.8 9095.6 9144.9 11064.9 9550.8 10453.4 7758.14 6963.81 10334.1 10092.6 TRUE FALSE FALSE 9465.222134 9881.783135 9483.818039 11019.11638 9436.912948 8285.247006 7975.812528 9087.043612 9200.475085 10443.3171 0.906342501 0.946230306 0.908123152 1.055135669 0.903631754 0.793353963 0.763724059 0.87013001 0.880991643 1 13.35029241 -5.408226493 4.200074413 0.956898959 0.805589932 0.572813242 0.053676543 0.112383132 3.327617242 0.007548173 0.017445877 3.91E-06 5.408226493 -0.151309027 GAS(ph)PDMAPILEPVDRR ddPTM_HeLa_Curcumin_4h_R1 1 GASPDMAPILEPVDRR 16 1 E9PDC2;A0A088AWP5;Q8WUY3-4;Q8WUY3;Q8WUY3-2;Q8WUY3-3;H7BZH9 E9PDC2 PRUNE2 Protein prune homolog 2 1 0 GAS(1)PDMAPILEPVDRR 158.45 0.00013176 20799000 2156.2 1864.5 2137.3 1982 2052.8 2367.4 1677.5 1245.1 2684.9 2103.9 TRUE FALSE FALSE 1985.534495 2025.659072 2216.510218 1973.799009 2028.321701 1876.374554 1724.566135 1624.725258 2390.373187 2177.010368 0.912046412 0.930477457 1.01814408 0.906655769 0.931700524 0.86190428 0.79217176 0.746310299 1.098007259 1 11.08813256 -4.802266562 0.969633972 0.958595369 0.709947738 0.697485665 0.054473361 0.337693117 0.401811399 0.006279041 0.071749728 1.58E-05 4.802266562 -0.248647631 GAS(ph)PLGPGSAAGSGAAASGGLGLGLGGR ddPTM_HeLa_Curcumin_4h_R1 1 GASPLGPGSAAGSGAAASGGLGLGLGGR 28 0 B4E1M0;E9PPE2;A0A6I8PS01;Q6P1R3-3;Q6P1R3 B4E1M0 MSANTD2 Myb/SANT-like DNA-binding domain-containing protein 2 1 0 GAS(1)PLGPGSAAGSGAAASGGLGLGLGGR 229.89 4.18E-73 0 465.58 323.3 301.64 298.96 259.93 127.11 154.16 142.54 497.33 306.53 TRUE FALSE FALSE 428.7288517 351.2446114 312.8190437 297.7229827 256.8305045 100.7459532 158.4853147 185.9997898 442.7741433 317.1818947 1.35168135 1.107391744 0.986244956 0.938650622 0.809726245 0.317628323 0.499666965 0.586413641 1.395962855 1 8.309166612 -5.767416302 1.285557263 1.159374044 0.464053493 0.816073842 0.143387801 0.151835316 0.498682533 0.025553957 0.067758738 1.71E-06 5.767416302 -0.695320551 SIS(ph)LSQSAENVPASK ddPTM_HeLa_Curcumin_4h_R1 1 SISLSQSAENVPASK 15 0 H0YFN7;Q4ADV7-2;Q4ADV7-3;Q4ADV7 H0YFN7 RIC1 RAB6A-GEF complex partner protein 1 1 0 SIS(0.99)LS(0.009)QSAENVPASK 231.21 5.92E-21 13613000 3209.3 2607.9 3173.6 3498.3 3119.6 3506.9 3921.7 8965.1 2658.6 3385.7 TRUE FALSE FALSE 2955.280519 2833.315255 3291.216408 3483.824962 3082.400807 2779.529409 4031.732347 11698.51772 2366.958231 3503.352823 0.843557777 0.808743909 0.939447602 0.994425951 0.8798431 0.793391231 1.150821099 3.339234816 0.675626564 1 11.77452057 -4.26139757 3.84769664 0.912494485 3.578604721 0.981354255 0.101440429 0.018337972 0.531222147 0.01130541 0.137426601 5.48E-05 4.26139757 2.666110235 up GASAATGIPLES(ph)DEDSNDNDNDIENENCMHTN ddPTM_HeLa_Curcumin_4h_R1 1 GASAATGIPLESDEDSNDNDNDIENENCMHTN 32 0 Q9Y4E8;Q9Y4E8-2;Q9Y4E8-3 Q9Y4E8;Q9Y4E8-2 USP15 Ubiquitin carboxyl-terminal hydrolase 15 1 0 GASAAT(0.019)GIPLES(0.762)DEDS(0.219)NDNDNDIENENCMHTN 119.46 1.10E-13 12074000 7174.5 5350.7 5691.9 6458.6 5765.9 7792.3 4261.1 3676.8 7065.7 5924.1 TRUE FALSE FALSE 6606.630755 5813.190666 5902.846821 6431.876025 5697.145408 6176.089143 4380.654998 4797.839394 6290.610388 6129.962034 1.077760469 0.94832409 0.96294998 1.04925218 0.929393262 1.00752486 0.714630037 0.782686641 1.026207072 1 12.58166242 -4.767185746 24.98209013 1.017534679 0.748658306 0.811375167 0.047927423 37.75998904 164163.3374 0.007593635 0.023717234 1.71E-05 4.767185746 -0.268876372 GASAATGIPLESDEDS(ph)NDNDNDIENENCMHTN ddPTM_HeLa_Curcumin_4h_R1 1 GASAATGIPLESDEDSNDNDNDIENENCMHTN 32 0 Q9Y4E8;Q9Y4E8-2;Q9Y4E8-3 Q9Y4E8;Q9Y4E8-2 USP15 Ubiquitin carboxyl-terminal hydrolase 15 1 0 GASAATGIPLES(0.451)DEDS(0.549)NDNDNDIENENCMHTN 98.225 4.72E-09 9516100 4389.7 3652.5 3656.6 3960.6 3819.8 4278.5 2783.9 2111.3 4017 3534.9 TRUE FALSE FALSE 4042.250613 3968.205825 3792.116813 3944.212087 3774.25138 3391.090871 2862.008742 2755.025651 3576.34515 3657.737512 1.105123208 1.084879878 1.036738366 1.078320157 1.031854081 0.927100663 0.782453288 0.753204855 0.977747894 1 11.83673583 -4.933324891 1.843784818 1.054720799 0.747121357 0.900347756 0.036792842 0.085772655 0.545500091 0.006062109 0.028832429 1.17E-05 4.933324891 -0.307599442 GASDEEIK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GASDEEIKR 9 1 P25685 P25685 DNAJB1 DnaJ homolog subfamily B member 1 0 1 ; GASDEEIK(1)R;GASDEEIK(1)R 116.05 0.0005573 2268600 1645.4 1809.43 1408.12 1549.29 2355.07 2698.8 2138.92 2152.4 2141.27 1514.36 FALSE TRUE FALSE 1515.164854 1965.829067 1460.306166 1542.879448 2326.987328 2139.038458 2198.932339 2808.656852 1906.378038 1566.983897 0.966930711 1.254530484 0.931921616 0.984617296 1.485010364 1.365067288 1.403289684 1.792396754 1.216590701 1 10.61377464 -3.869408717 0.429675114 0.977341582 2.573973758 0.665099733 0.153169759 2.208731305 0.216303115 0.031598778 1.931425581 0.00013508 3.869408717 1.596632176 GASDEEIKR ddPTM_HeLa_Curcumin_4h_R1 1 GASDEEIKR 9 1 P25685 P25685 DNAJB1 DnaJ homolog subfamily B member 1 0 0 74.301 0.018535 1330000 1787 1710 1599.6 1506.8 1793.4 1700.6 1502 1689 1583.4 1510.4 FALSE FALSE TRUE 1645.557064 1857.80478 1658.882583 1500.565261 1772.014876 1347.87639 1544.142078 2203.968325 1409.704981 1562.886288 1.05289622 1.188701184 1.061422444 0.960124401 1.133809216 0.862427677 0.988006671 1.410191095 0.901988195 1 10.6099971 -4.257681331 24.97584363 1.029034859 1.410191243 0.607281316 0.094479163 174.9922382 1162941.24 0.011487664 0.115765719 5.52E-05 4.257681331 0.381156384 GASGTVLLAGSSLMAS(ph)PYK ddPTM_HeLa_Curcumin_4h_R1 1 GASGTVLLAGSSLMASPYK 19 0 Q9NPG3;Q9NPG3-2 Q9NPG3 UBN1 Ubinuclein-1 1 0 GASGTVLLAGS(0.039)S(0.039)LMAS(0.923)PYK 123.19 0.00063699 0 861.59 603.79 497.4 667.04 832.62 904.08 625.34 320.81 946.14 691.75 TRUE FALSE FALSE 793.3942424 655.9789172 515.8340816 664.2799652 822.6915503 716.5636169 642.8853574 418.6234922 842.3508091 715.788261 1.108420305 0.916442687 0.720651776 0.928039759 1.149350437 1.00108322 0.898150183 0.584842634 1.176815624 1 9.483389073 -7.174530323 6.477074002 1.051040837 0.894927416 0.276109547 0.150188794 0.309141529 19.32409531 0.025122441 0.030814524 6.69E-08 7.174530323 -0.156113421 GASQAGMTGY(ph)GRPR ddPTM_HeLa_Curcumin_4h_R1 1 GASQAGMTGYGRPR 14 1 Q01995;H0YCU9 Q01995 TAGLN Transgelin 1 0 GASQAGMT(0.019)GY(0.981)GRPR 68.262 0.011759 702270 151.94 186.51 121.48 160.8 0 173.44 169.53 103.18 334.56 138.17 TRUE FALSE FALSE 139.9137887 202.6310933 125.9821557 160.1346522 0 137.4665889 174.2865555 134.639107 297.859605 142.9713972 0.978613844 1.417284137 0.881170347 1.120046774 0 0.961497136 1.219030932 0.941720579 2.083351012 1 7.159582741 GASQAGMTGYGMPR ddPTM_HeLa_Curcumin_4h_R1 4 GASQAGMTGYGMPR 14 0 P37802;P37802-2;C9J5W6;Q9UI15 P37802 TAGLN2;TAGLN3 Transgelin-2;Transgelin-3 0 0 ;;; ;;; 153.75 0.00091654 15056400 3603.73 3254.08 3204.51 3047.39 3462.55 3892.37 3289.1 3121.36 3794.79 3266.15 FALSE FALSE TRUE 3318.490968 3535.348175 3323.27196 3034.780708 3421.261353 3085.048586 3381.383294 4073.048295 3378.511031 3379.648469 0.981904183 1.046069793 0.983318824 0.897957505 1.012312785 0.912831205 1.000513315 1.205169216 0.999663445 1 11.72265748 -4.266847056 5.024398162 0.984345848 1.21510835 0.71849867 0.042054814 0.062379584 4.926259194 0.005525786 0.049529064 5.41E-05 4.266847056 0.230762501 GASQAGMTGYGRPR ddPTM_HeLa_Curcumin_4h_R1 2 GASQAGMTGYGRPR 14 1 Q01995;H0YCU9 Q01995 TAGLN Transgelin 0 0 ; ; 171.36 1.69E-05 7579000 3571.1 2769 3031.5 3182.8 3081.9 3687.7 2780.7 2966.3 3997.1 3485.3 FALSE FALSE TRUE 3288.443667 3008.340022 3143.850057 3169.630417 3045.150355 2922.829451 2858.718958 3870.711215 3558.62813 3606.413916 0.911832015 0.834163824 0.871738555 0.87888703 0.844370731 0.810453131 0.792676333 1.073285348 0.986749778 1 11.81634927 -8.272267286 0.739734572 0.991909519 0.865449663 0.280492127 0.07390004 0.502830108 0.592854433 0.028896131 0.016688822 5.34E-09 8.272267286 -0.126459857 GASSPYGAPGT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 GASSPYGAPGTPR 13 0 Q5UIP0-2;Q5UIP0;H7BZN3 Q5UIP0-2 RIF1 Telomere-associated protein RIF1 1 0 GASSPYGAPGT(1)PR 142.39 0.0013144 0 1686.7 1585.3 1399.2 1647.2 1571.7 2193.8 2017 1157.7 1613.6 1808.5 TRUE FALSE FALSE 1553.195915 1722.326268 1451.055583 1640.384323 1552.958504 1738.781151 2073.591592 1510.677401 1436.592117 1871.34524 0.829988974 0.920367996 0.77540774 0.876580274 0.829862107 0.929161073 1.108075382 0.807268145 0.767678826 1 10.86986003 -3.960964079 16.49738304 0.911369255 0.348673986 0.034421819 0.100277189 27359529.4 310390135.2 0.013602629 463824682.7 0.000109405 3.960964079 -0.562695269 GASTFK(ac)EEPQTVPEAR ddPTM_HeLa_Curcumin_4h_R1 2 GASTFKEEPQTVPEAR 16 1 P17275 P17275 JUNB Transcription factor jun-B 0 1 ; GASTFK(1)EEPQTVPEAR;GASTFK(1)EEPQTVPEAR 298.78 6.05E-113 9633600 2747.1 2296.01 3238.2 2259.53 2461.7 2854.6 1657.32 1384.74 2276.96 2506.1 FALSE TRUE FALSE 2529.664136 2494.466874 3358.210541 2250.180664 2432.345835 2262.523782 1703.819939 1806.940851 2027.183185 2593.186788 0.97550402 0.961931044 1.295012976 0.867727953 0.937975562 0.872487779 0.657037104 0.6968032 0.781734349 1 11.34051041 -5.006558938 1.387281777 1.002948759 0.651886847 0.455931899 0.126238022 0.253107066 0.841029961 0.015146889 0.083803807 9.85E-06 5.006558938 -0.351061912 GAT(ph)ENS(ph)VY(ph)LGMYRGQLYLQS(ph)SVR ddPTM_HeLa_Curcumin_4h_R1 1 GATENSVYLGMYRGQLYLQSSVR 23 1 Q9NZJ5 Q9NZJ5 EIF2AK3 Eukaryotic translation initiation factor 2-alpha kinase 3 4 0 GAT(0.994)ENS(0.993)VY(0.874)LGMY(0.116)RGQLY(0.024)LQS(0.5)S(0.5)VR 53.553 0.0065362 0 1097.8 1112.8 1202.1 1284.5 1014 1296.9 1073.4 1469.8 1084.8 1119.2 TRUE FALSE FALSE 1010.907972 1208.985473 1246.650883 1279.185079 1001.908712 1027.908321 1103.516715 1917.935254 965.800154 1158.092117 0.872908085 1.043945862 1.076469536 1.104562462 0.865137322 0.887587702 0.952874732 1.656116319 0.833957973 1 10.1775343 -4.261179957 24.72118022 0.95802968 1.656116558 0.843626219 0.089944464 5.074260426 483225.4458 0.012590938 0.098277667 5.48E-05 4.261179957 0.698086878 GATGGREGRGTQPVPDPQS(ph)S(ph)KPVMEK ddPTM_HeLa_Curcumin_4h_R1 1 GATGGREGRGTQPVPDPQSSKPVMEK 26 3 E9PB28 E9PB28 HES4 2 0 GAT(0.003)GGREGRGT(0.003)QPVPDPQS(0.995)S(0.999)KPVMEK 51.234 0.0061949 13160000 824.06 642 635.21 750.44 1085 1331.9 1009.9 492.96 982.89 836.39 TRUE FALSE FALSE 758.8347815 697.4916193 658.7514414 747.3348781 1072.062084 1055.648926 1038.235076 643.2612347 875.0694261 865.4544902 0.87680495 0.805925242 0.761162428 0.863517246 1.238727277 1.219762493 1.199641446 0.743264079 1.011109695 1 9.757314148 -5.77506265 24.96917603 0.909195646 1.115970714 0.318666239 0.150365951 214.6260234 393373.5711 0.0224685 0.040888083 1.68E-06 5.77506265 0.206775068 GATPGK(ac)ALVATPGK ddPTM_HeLa_Curcumin_4h_R1 2 GATPGKALVATPGK 14 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 ; GATPGK(1)ALVATPGK;GATPGK(1)ALVATPGK 215.02 6.19E-27 95999000 9643.4 7324.7 8379.4 8701.7 7606.3 11087 10751.1 10883 9025.8 7786.3 FALSE TRUE FALSE 8880.114714 7957.81443 8689.947935 8665.694671 7515.59984 8787.431224 11052.74693 14201.1766 8035.692321 8056.873345 1.102178765 0.987705042 1.078575716 1.075565458 0.932818417 1.09067511 1.37184072 1.762616339 0.997371062 1 12.97600436 -4.433246353 1.936557338 1.040929321 1.851479243 0.953299263 0.051105187 0.086072808 0.437588704 0.007980054 0.109356819 3.69E-05 4.433246353 0.810549922 GATPGK(ac)ALVATPGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 GATPGKALVATPGKK 15 2 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 2 ; GATPGK(1)ALVATPGK(1)K;GATPGK(1)ALVATPGK(1)K 201.48 5.61E-18 5363500 3917.7 2902.1 2874.3 2920.5 2802.8 4563.5 3488.2 3638.4 3910.4 3080.2 FALSE TRUE FALSE 3607.609911 3152.944592 2980.824086 2908.415745 2769.378441 3616.978659 3586.069504 4747.731411 3481.438903 3187.236721 1.131892679 0.989240797 0.935237746 0.912519527 0.868896377 1.134832137 1.125134346 1.489607402 1.092306348 1 11.63809046 -4.105617767 1.632114418 1.027500478 1.799272047 0.739897936 0.085708566 0.718063222 1.332055648 0.014400759 0.980677585 7.84E-05 4.105617767 0.771771569 GATQQILDEAER ddPTM_HeLa_Curcumin_4h_R1 4 GATQQILDEAER 12 0 F5GWF6;P78371;F8VQ14;P78371-2 F5GWF6 CCT2 T-complex protein 1 subunit beta 0 0 ;;; ;;; 184.03 1.24E-09 33081600 7939.6 6533.2 7116.9 6870.4 7493.6 9416.8 6553.2 6955.9 8163.9 6772.8 FALSE FALSE TRUE 7311.172282 7097.900697 7380.658575 6841.972105 7404.243714 7463.649531 6737.065155 9076.721889 7268.340595 7008.154296 1.043237916 1.012805997 1.053152979 0.97628731 1.056518364 1.064995035 0.96131804 1.295165818 1.037126223 1 12.77481882 -4.253594868 24.99043694 1.021954589 1.295165951 0.858162281 0.033213899 242.0859298 771200.5005 0.004320084 0.062780435 5.58E-05 4.253594868 0.273211362 GAVECCPNCR ddPTM_HeLa_Curcumin_4h_R1 1 GAVECCPNCR 10 0 P31689;P31689-2 P31689 DNAJA1 DnaJ homolog subfamily A member 1 0 0 123.92 0.0023497 1108900 316.32 302.07 421.07 292.67 259.85 447.92 381.52 175.03 271.68 163.63 FALSE FALSE TRUE 291.2829382 328.1795848 436.6752246 291.4590091 256.7514585 355.0163429 392.2244244 228.3958413 241.8773837 169.3161303 1.720349607 1.938265328 2.579052709 1.721389501 1.516402826 2.096766222 2.316521312 1.34893138 1.428554877 1 7.403575611 -8.561535993 0.710148339 1.02773689 1.945419188 0.349014419 0.364789316 0.398582111 0.409835357 0.182255333 0.079664864 2.74E-09 8.561535993 0.917682298 GAVEK(ac)GEELSCEER ddPTM_HeLa_Curcumin_4h_R1 2 GAVEKGEELSCEER 14 1 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 1 ; GAVEK(1)GEELSCEER;GAVEK(1)GEELSCEER 246.25 7.60E-49 5137100 667.66 715.37 578.64 493.24 807.33 1322.11 822.74 863.84 1514.57 501.04 FALSE TRUE FALSE 614.8140065 777.2033952 600.0849074 491.1991036 797.703117 1047.889483 845.8238701 1127.220839 1348.42546 518.4511027 1.185866909 1.499087168 1.157457095 0.947435739 1.538627487 2.021192505 1.631443864 2.174208587 2.600872972 1 9.018064119 -1.000000209 0.272026121 1.025372833 9.353955677 0 0.53693218 18.46611773 0.234451015 0.100405973 73.34178724 0.099999952 1.000000209 8.328582844 GAVEKGEELSCEER ddPTM_HeLa_Curcumin_4h_R1 1 GAVEKGEELSCEER 14 1 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 0 108.68 0.0027349 13746000 1169 968.38 1128.6 1308 1102.4 1485.7 1058.5 1103 1341.1 1025.3 FALSE FALSE TRUE 1076.472416 1052.082452 1170.426909 1302.587843 1089.2546 1177.549073 1088.198661 1439.299622 1193.984685 1060.929099 1.014650666 0.991661416 1.103209357 1.227780296 1.026698769 1.109922495 1.025703473 1.356640726 1.125414212 1 10.05111253 -1 0.306160274 1.00356492 3.154921465 0.305576253 0.092355175 33.97029201 0.434438965 0.029792277 40.86805994 0.1 1 2.151356545 GAVQTAGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 GAVQTAGKK 9 1 P46087-2;F5H5X6;P46087-3 P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 0 1 GAVQTAGK(1)K 122.28 0.00039729 1956400 1863.8 1717 2138.3 1698.4 1547.8 2282.8 1551.8 1345.6 1955.6 1756.3 FALSE TRUE FALSE 1716.278263 1865.409829 2217.547279 1691.372471 1529.343496 1809.321548 1595.339332 1755.867246 1741.075573 1817.331294 0.944394822 1.02645557 1.220221809 0.930690225 0.841532582 0.995592578 0.877847279 0.966178952 0.958039725 1 10.82760573 -6.029132877 24.99428774 0.998184918 0.918069724 0.253647996 0.083909467 963.4614188 826591.9441 0.013083036 0.021720281 9.35E-07 6.029132877 -0.080115195 GAVSAEQVIAGFNR ddPTM_HeLa_Curcumin_4h_R1 2 GAVSAEQVIAGFNR 14 0 Q9UHV9 Q9UHV9 PFDN2 Prefoldin subunit 2 0 0 ; ; 167.84 5.66E-05 3720700 2319 2632.5 1572.34 2116.4 2684.4 1231.01 1154.91 1199.36 2895.2 1730.99 FALSE FALSE TRUE 2135.448703 2860.04157 1630.612304 2107.642898 2652.390283 975.6846497 1187.313666 1565.039343 2577.603803 1791.141774 1.192227625 1.596770067 0.9103759 1.176703558 1.48083771 0.544727762 0.662880897 0.873766313 1.439084187 1 10.80666382 -5.246153952 24.89487046 1.146884784 0.690700564 0.520387304 0.231377125 514.6377989 838171.7861 0.030598254 0.077690985 5.67E-06 5.246153952 -0.45618422 GAVY(ph)QAPSPPPAPVGLGSMAVFR ddPTM_HeLa_Curcumin_4h_R1 1 GAVYQAPSPPPAPVGLGSMAVFR 23 0 Q13057-2;K7EPT0;K7ESK6 Q13057-2 COASY Bifunctional coenzyme A synthase;Phosphopantetheine adenylyltransferase;Dephospho-CoA kinase 1 0 GAVY(0.726)QAPS(0.272)PPPAPVGLGS(0.002)MAVFR 93.243 0.00091408 10957000 3422.8 2699.7 2796.8 2793.3 2740.1 4060.4 2805.2 1854 3184.2 3134.1 TRUE FALSE FALSE 3151.881768 2933.050038 2900.451868 2781.742065 2707.426097 3218.22727 2883.906362 2419.276065 2834.901226 3243.009742 0.971900185 0.90442221 0.894370384 0.857765559 0.834849819 0.992358188 0.889268486 0.745997162 0.874157481 1 11.66311764 -7.184703124 1.358147853 0.990777716 0.871086407 0.145142344 0.068041685 0.262756667 0.929064039 0.011007425 0.013496215 6.54E-08 7.184703124 -0.119691309 GCALQCAILS(ph)PAFK ddPTM_HeLa_Curcumin_4h_R1 1 GCALQCAILSPAFK 14 0 A0A0A0MSM0;Q92598-2;Q92598-3;Q92598;Q92598-4;D6RJ96;E9PDE8;O95757;P34932;A0A087WYC1;A0A087WTS8 A0A0A0MSM0;D6RJ96;P34932 HSPH1;HSPA4L;HSPA4 Heat shock protein 105 kDa;Heat shock 70 kDa protein 4L;Heat shock 70 kDa protein 4 1 0 GCALQCAILS(1)PAFK 111.12 0.0028021 17755000 1805.8 1516.5 1548.7 1774.8 1369.5 2078.1 1745.3 1429.2 1875.4 1547.3 TRUE FALSE FALSE 1662.869025 1647.579503 1606.096184 1767.456348 1353.169607 1647.078635 1794.268421 1864.956501 1669.673312 1601.06856 1.038599512 1.029049938 1.003140168 1.103922963 0.84516656 1.028737105 1.120669324 1.164819888 1.042849353 1 10.64481937 -4.709969585 3.739174079 1.012295565 1.152995825 0.423877516 0.062266216 0.149873427 4.186857279 0.008131655 0.03381695 1.95E-05 4.709969585 0.14070026 S(ph)IGSAVDQGNESIVAK ddPTM_HeLa_Curcumin_4h_R1 2 SIGSAVDQGNESIVAK 16 0 Q9H0H5;F8VRD2;F8W1E5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 0 S(0.995)IGS(0.004)AVDQGNESIVAK;S(0.788)IGS(0.212)AVDQGNESIVAK ; 153.2 0.0003288 97042000 5822 3688.9 4601.5 5352.8 4377 5751.8 2730.8 1366.84 5887.7 4125.5 TRUE FALSE FALSE 5361.182557 4007.752079 4772.035638 5330.651532 4324.807134 4558.811844 2807.418898 1783.583224 5241.83404 4268.860818 1.255881319 0.938834094 1.117870983 1.248729289 1.013105678 1.067922342 0.657650605 0.417812456 1.227923388 1 12.05963541 -4.612162854 2.021823446 1.113428311 0.391678403 0.83683615 0.103581018 0.127092348 0.873965798 0.016580549 0.129735414 2.44E-05 4.612162854 -0.721749908 down GCDVVVIPAGVPR ddPTM_HeLa_Curcumin_4h_R1 1 GCDVVVIPAGVPR 13 0 P40926;P40926-2 P40926 MDH2 "Malate dehydrogenase, mitochondrial" 0 0 109.83 0.0022612 5571600 2545.1 2152.6 2416.4 2544 3003.1 2748.2 2289.3 2176.2 3329.4 2165.2 FALSE FALSE TRUE 2343.652649 2338.661152 2505.95391 2533.473602 2967.289994 2178.192341 2353.531597 2839.713362 2964.17315 2240.440539 1.046067775 1.043839866 1.118509448 1.130792609 1.32442256 0.97221609 1.050477152 1.267479905 1.323031385 1 11.12956672 -6.783956539 2.000611678 1.021412863 1.143077083 0 0.133535214 0.328414948 2.691603544 0.015567605 0.022124854 1.64E-07 6.783956539 0.121664221 GCES(ph)PDPDSSYALTPR ddPTM_HeLa_Curcumin_4h_R1 1 GCESPDPDSSYALTPR 16 0 Q06413-5;A0A0D9SGI5;Q06413-6;A0A0D9SFD0;D6RC63;D6R942;A0A0D9SET2;D6RB91 Q06413-5 MEF2C Myocyte-specific enhancer factor 2C 1 0 GCES(0.991)PDPDS(0.004)S(0.004)YALTPR 135.86 0.00042499 7309600 1780.1 1236.3 1478.5 1447.6 1535.4 2107.9 1385.6 357.56 1959.2 1963.7 TRUE FALSE FALSE 1639.203207 1343.160263 1533.294511 1441.610215 1517.091358 1670.697779 1424.476207 466.578398 1744.280662 2031.938429 0.806718936 0.661024096 0.754596935 0.709475343 0.746622701 0.822218703 0.701042997 0.229622311 0.858431849 1 10.98864097 -4.206569007 0.124489336 1.137302874 1.08E-15 0.483835624 0.136514331 20.40402577 0.416626519 0.757647758 4.090556893 6.21E-05 4.206569007 -1.137302874 GCEVVVSGK ddPTM_HeLa_Curcumin_4h_R1 1 GCEVVVSGK 9 0 E9PL09;P23396;P23396-2;H0YEU2;E9PSF4;E9PJN9 E9PL09 RPS3 40S ribosomal protein S3 0 0 162.97 1.13E-08 7466800 4984.9 4306.5 4430.7 4779.5 4618.9 4590.8 4315.1 4004.1 4790.9 4528.7 FALSE FALSE TRUE 4590.339905 4678.734671 4594.90564 4759.723695 4563.822634 3638.616331 4436.170093 5224.931657 4265.350256 4686.071988 0.979570932 0.998434229 0.980545252 1.015717152 0.97391219 0.776474698 0.946671349 1.114991761 0.910218679 1 12.1941634 -5.508941229 24.95586779 0.991699515 0.934289316 0.019431095 0.080817009 1125.15083 2014641.389 0.010593344 0.022816119 3.10E-06 5.508941229 -0.057410199 GCGVVK(ac)FESPEVAER ddPTM_HeLa_Curcumin_4h_R1 1 GCGVVKFESPEVAER 15 1 A0A087X0X3;P52272-2;P52272 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 1 GCGVVK(1)FESPEVAER 173.68 6.60E-05 2951600 596.17 438.02 434.63 614.7 541.11 769.61 381.27 441.02 541.3 432.23 FALSE TRUE FALSE 548.9825154 475.880497 450.7377701 612.1565343 534.6576167 609.9842107 391.9674101 575.4849678 481.9207443 447.2499603 1.227462413 1.064014621 1.007798346 1.368712328 1.19543357 1.36385526 0.876394511 1.286718879 1.077519926 1 8.804937544 -9.453960934 0.962831955 0.990198428 1.174001904 0.107698992 0.149491694 0.926309546 1.396735277 0.127710044 0.02555948 3.52E-10 9.453960934 0.183803476 GCITIIGGGDTATCCAK ddPTM_HeLa_Curcumin_4h_R1 1 GCITIIGGGDTATCCAK 17 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 0 187.63 5.04E-08 3911900 3055.4 2497.3 2683.3 2882.3 3055.5 6247.1 2955.6 2400.6 3364.3 2948.6 FALSE FALSE TRUE 2813.561866 2713.155484 2782.745458 2870.373806 3019.065158 4951.381041 3038.526181 3132.531889 2995.244707 3051.063631 0.922157715 0.889249066 0.912057497 0.940778087 0.989512355 1.622837686 0.995890794 1.026701593 0.981705094 1 11.57509655 -5.492346881 24.99965382 0.951133757 1.21204427 0.368389574 0.161074982 546.928526 447827.6615 0.021818415 0.04872765 3.22E-06 5.492346881 0.260910513 GCLDEETSR ddPTM_HeLa_Curcumin_4h_R1 1 GCLDEETSR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 189.82 0.0082483 16452000 3441.8 2902.6 3710.9 3488.4 3114 3869.6 3177.8 2788.5 3476 3568.4 FALSE FALSE TRUE 3169.377898 3153.48781 3848.429218 3473.965925 3076.867584 3067.001341 3266.960515 3638.700813 3094.691497 3692.401634 0.858351342 0.854047886 1.042256396 0.940841834 0.833297103 0.830625063 0.884779295 0.985456398 0.83812429 1 11.85034377 -5.794501803 24.7351636 0.934543072 0.879848382 0.04724782 0.072989732 305.2009605 228330.7417 0.011559308 0.020954112 1.61E-06 5.794501803 -0.05469469 GCLLYGPPGTGK ddPTM_HeLa_Curcumin_4h_R1 1 GCLLYGPPGTGK 12 0 A0A087X2I1;P62333;H0YJS8;H0YJC0 A0A087X2I1 PSMC6 26S protease regulatory subunit 10B 0 0 136.99 0.00023203 1786300 1222.1 976.22 1211.4 1282.1 1548.3 1573.3 1100.9 1055.4 1415.6 1251.6 FALSE FALSE TRUE 1125.369495 1060.600107 1256.29555 1276.79501 1529.837534 1246.979845 1131.788291 1377.186602 1260.312222 1295.093007 0.868948786 0.818937405 0.970042725 0.985871287 1.181256887 0.962849648 0.873905029 1.063388185 0.97314418 1 10.33883999 -6.372722573 3.680812015 0.926559952 1.012280297 0.210253157 0.087447337 0.363740445 8.969280583 0.014956829 0.02340403 4.24E-07 6.372722573 0.085720345 GCLTTPNS(ph)PSMHSR ddPTM_HeLa_Curcumin_4h_R1 1 GCLTTPNSPSMHSR 14 0 O75128-3;O75128;O75128-7;A0A0J9YWK3;A0A3B3IU00;O75128-5;O75128-4 O75128-3 COBL Protein cordon-bleu 1 0 GCLTT(0.003)PNS(0.989)PS(0.008)MHSR 73.735 0.01299 5026800 3040.3 2552.8 2334.2 2573.2 3259.1 3486.1 2568.7 1606.7 2966.1 2317.9 TRUE FALSE FALSE 2799.657047 2773.452657 2420.707505 2562.55278 3220.237361 2763.043564 2640.770809 2096.575434 2640.726251 2398.446852 1.167279168 1.156353602 1.009281278 1.068421749 1.342634446 1.152013671 1.101033699 0.874138792 1.101015121 1 11.22788476 -9.462824701 1.190424961 0.999777613 1.119971047 0.003266492 0.11789344 0.812107548 2.052932044 0.080026588 0.019622461 3.44E-10 9.462824701 0.120193434 GCSFLPDPYQK ddPTM_HeLa_Curcumin_4h_R1 1 GCSFLPDPYQK 11 0 Q5BJH1;C9JIZ6;P07602;P07602-2;P07602-3 Q5BJH1 PSAP Prosaposin;Saposin-A;Saposin-B-Val;Saposin-B;Saposin-C;Saposin-D 0 0 105.2 0.00617 1685700 3477.9 2969 2741.5 3303.4 2679 3783.9 3416.7 3365.4 3913.4 2699.7 FALSE FALSE TRUE 3202.620545 3225.62713 2843.102402 3289.731406 2647.054675 2999.076487 3512.563406 4391.494968 3484.109811 2793.514374 1.146448565 1.154684279 1.017751127 1.177631816 0.947571525 1.073585486 1.257399439 1.572032351 1.247213848 1 11.44786553 -4.363813871 2.202325395 1.072140024 1.643368321 0.724626917 0.088715673 0.161797185 1.043821102 0.010933304 0.164589038 4.33E-05 4.363813871 0.571228296 GCT(ph)PSGEGADSEPR ddPTM_HeLa_Curcumin_4h_R1 1 GCTPSGEGADSEPR 14 0 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 1 0 GCT(0.74)PS(0.26)GEGADSEPR 119.88 0.0052166 4719800 3226.1 2887 2727.6 2750.8 2807.6 3803.7 3057 3903.3 3483.5 2902 TRUE FALSE FALSE 2970.750781 3136.539416 2828.687255 2739.417918 2774.121204 3014.769743 3142.771193 5093.398201 3101.368765 3002.844284 0.989312299 1.044522832 0.942002644 0.912274384 0.923831188 1.003971388 1.046598123 1.696191251 1.032810386 1 11.55211395 -4.255043624 3.736059862 0.984834381 1.775981915 0.963220665 0.041661382 0.035397047 0.919220499 0.005844841 0.077708606 5.56E-05 4.255043624 0.791147535 GCTIVKPFNLSQGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 GCTIVKPFNLSQGKK 15 2 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 0 1 ; GCTIVKPFNLSQGK(1)K;GCTIVKPFNLSQGK(1)K 208.79 2.40E-19 15611600 6766.6 6530.9 6303.2 5176.8 5419.7 9180.4 5867 2858.4 6343.5 6821.3 FALSE TRUE FALSE 6231.01647 7095.401895 6536.802137 5155.379773 5355.073617 7276.281556 6031.61223 3729.913002 5647.633921 7058.339667 0.882787846 1.005250842 0.926110452 0.730395534 0.758687435 1.030877217 0.854536975 0.528440565 0.800136319 1 12.78511314 -6.376647685 6.12064495 0.948342551 0.797805996 0.215340396 0.1297971 0.253777611 12.00486514 0.01896165 0.029063121 4.20E-07 6.376647685 -0.150536556 GCTPSGEGADSEPR ddPTM_HeLa_Curcumin_4h_R1 1 GCTPSGEGADSEPR 14 0 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 0 0 141.1 0.001005 250640 0 121.92 119.95 119.94 0 0 54.763 0 0 0 FALSE FALSE TRUE 0 132.4582215 124.3954525 119.4437201 0 0 56.29950239 0 0 0 0 GCWEVS(ph)PTER ddPTM_HeLa_Curcumin_4h_R1 1 GCWEVSPTER 10 0 Q8IZT6-2;Q8IZT6 Q8IZT6-2 ASPM Abnormal spindle-like microcephaly-associated protein 1 0 GCWEVS(0.948)PT(0.052)ER 139.31 0.0016032 5887800 1707.3 1336.6 1673.6 1928.4 1667.6 2250.3 1631.7 1134.4 2081.2 1818.6 TRUE FALSE FALSE 1572.165403 1452.129748 1735.625088 1920.420792 1647.714959 1783.562414 1677.481111 1480.273338 1852.897567 1881.796215 0.835459967 0.771672159 0.922323615 1.020525377 0.875607543 0.947797854 0.891425489 0.786627865 0.984643051 1 10.87789469 -9.446831244 1.218239096 0.999089192 0.881344534 0.286143844 0.069927312 0.505895883 1.359098016 0.048797305 0.012543895 3.57E-10 9.446831244 -0.117744657 GDAAS(ph)SPAPAASVGSSQGGAR ddPTM_HeLa_Curcumin_4h_R1 1 GDAASSPAPAASVGSSQGGAR 21 0 F8WCC1;E7EXA6;A0A0D9SF58;Q8WVB6;Q8WVB6-2 F8WCC1 CHTF18 Chromosome transmission fidelity protein 18 homolog 1 0 GDAAS(0.708)S(0.292)PAPAASVGSSQGGAR 197.94 2.38E-13 95728000 3921.8 2838.6 3292.1 3531.5 3163.8 3663 2997.1 1395 3774.4 3322 TRUE FALSE FALSE 3611.385392 3083.955935 3414.108122 3516.887589 3126.073751 2903.252509 3081.19056 1820.329078 3360.357763 3437.439253 1.050603407 0.897166672 0.993212642 1.023112652 0.909419344 0.844597474 0.896362185 0.529559636 0.977575898 1 11.7471185 -3.781223857 0.714588032 1.011964051 1.66E-22 0.808209601 0.062161294 1.450106938 0.324626231 0.010027803 1.386554385 0.000165492 3.781223857 -1.011964051 GDAASS(ph)PAPAASVGSSQGGAR ddPTM_HeLa_Curcumin_4h_R1 1 GDAASSPAPAASVGSSQGGAR 21 0 F8WCC1;E7EXA6;A0A0D9SF58;Q8WVB6;Q8WVB6-2 F8WCC1 CHTF18 Chromosome transmission fidelity protein 18 homolog 1 0 GDAAS(0.077)S(0.923)PAPAASVGSSQGGAR 332.37 5.49E-139 96203000 3176.5 2327.6 2672.9 3385.2 2698.1 3259.8 2590.5 1277 3885.7 2686.7 TRUE FALSE FALSE 2925.076673 2528.787372 2771.960025 3371.192939 2665.92692 2583.680734 2663.182458 1666.351421 3459.448432 2780.062625 1.052162152 0.909615255 0.997085461 1.212632014 0.958944916 0.929360623 0.957957722 0.599393484 1.244377879 1 11.44090167 -3.872963664 1.325119227 1.02185734 1.99E-16 0.605458925 0.105637651 1.314704479 0.999571005 0.011268 2.322335531 0.000133979 3.872963664 -1.02185734 GDADMY(ph)DLPKKEDALLYQS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 GDADMYDLPKKEDALLYQSK 20 2 Q5HY57;P50402 Q5HY57 EMD Emerin 2 0 GDADMY(1)DLPKKEDALLY(0.037)QS(0.963)K 51.31 0.013644 14618000 714.81 617 792.98 931.88 745.5 733.84 1011.6 974.77 797.82 1060.9 TRUE FALSE FALSE 658.2320342 670.3307307 822.3685364 928.0241275 736.6103994 581.6333119 1039.982773 1271.972886 710.301142 1097.766196 0.599610406 0.610631602 0.74912904 0.845375027 0.671008455 0.529833506 0.947362724 1.158691979 0.64704228 1 10.1003551 -4.525345491 24.78944241 0.764901032 1.105859761 0.487440001 0.139237523 50.50970934 507606.985 0.025071875 0.095036836 2.98E-05 4.525345491 0.340958729 GDAEKPEEELEEDDDEELDETLSER ddPTM_HeLa_Curcumin_4h_R1 1 GDAEKPEEELEEDDDEELDETLSER 25 1 Q9NS69 Q9NS69 TOMM22 Mitochondrial import receptor subunit TOM22 homolog 0 0 168.86 6.10E-12 24722000 2506.8 1880.9 2340.2 2545.4 2506.1 3369.3 2343.7 1465.5 2448.9 2725.3 FALSE FALSE TRUE 2308.384135 2043.476615 2426.929871 2534.867809 2476.216394 2670.4692 2409.457914 1912.324204 2180.261797 2820.003972 0.818574781 0.724636077 0.860612217 0.898888028 0.878089683 0.94697356 0.854416497 0.678128195 0.773141392 1 11.46148148 -9.199896272 0.955170662 0.999481765 0.838340877 0 0.102378621 0.469716409 0.77466688 0.051084589 0.014576294 6.31E-10 9.199896272 -0.161140887 GDAPVDKVELSEDSPNS(ph)EQDLEK ddPTM_HeLa_Curcumin_4h_R1 2 GDAPVDKVELSEDSPNSEQDLEK 23 1 Q5T5P2;Q5T5P2-3;Q5T5P2-7;Q5T5P2-8;Q5T5P2-6;Q5T5P2-9;Q5T5P2-2;Q5T5P2-4 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 0 GDAPVDKVELS(0.002)EDS(0.315)PNS(0.683)EQDLEK;GDAPVDKVELS(0.001)EDS(0.392)PNS(0.607)EQDLEK ; 84.107 0.00017855 18220400 5189.4 3964.6 4931.6 4241 4765.4 5927.8 3974.5 3291.9 5647 4651.3 TRUE FALSE FALSE 4778.653514 4307.282358 5114.369434 4223.451866 4708.575717 4698.30746 4086.013773 4295.585156 5027.538228 4812.932329 0.992877769 0.894939314 1.062630655 0.877521556 0.978317457 0.976183985 0.848965557 0.892508945 1.044589428 1 12.23270042 -1 0.255611025 1.00264721 0.112608383 0.361734327 0.055802442 34.93149835 0.438254526 0.025549656 13.63203057 0.1 1 -0.890038827 GDAVRDVDIIDHHDNTYTVK ddPTM_HeLa_Curcumin_4h_R1 1 GDAVRDVDIIDHHDNTYTVK 20 1 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 100.77 0.00012098 11355000 5640.1 3430.2 2839 3803.9 1728 4887.3 2653.4 3304.1 8277.1 6342.4 FALSE FALSE TRUE 5193.680134 3726.691203 2944.215837 3788.16047 1707.394729 3873.618889 2727.847263 4311.50488 7369.122838 6562.797928 0.791381998 0.567850975 0.448622047 0.577217295 0.260162624 0.590238939 0.415653094 0.656961395 1.12286298 1 12.6800953 -7.497847187 0.966639763 0.947447625 0.475674644 0.760025031 0.122832206 0.153128741 0.291548539 0.025070127 0.026308754 3.18E-08 7.497847187 -0.471772981 GDDALEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GDDALEKR 8 1 Q9Y617 Q9Y617 PSAT1 Phosphoserine aminotransferase 0 1 ; GDDALEK(1)R;GDDALEK(1)R 92.439 0.006852 6549600 6094.1 5978.1 6033.6 6304.2 6397.2 7085.1 6553.4 6527.4 6748.3 5910.8 FALSE TRUE FALSE 5611.745555 6494.820326 6257.210524 6278.114891 6320.917568 5615.570394 6737.270766 8517.574212 6008.028373 6116.19986 0.917521612 1.061904528 1.023055274 1.026473143 1.03347139 0.918146974 1.101545228 1.392625226 0.982313939 1 12.57841984 -4.325191981 2.693381642 0.979553189 1.443720227 0.859458314 0.047947123 0.108950349 1.133701535 0.00773925 0.104646396 4.73E-05 4.325191981 0.464167038 GDDDEES(ph)DEEAVK ddPTM_HeLa_Curcumin_4h_R1 2 GDDDEESDEEAVK 13 0 O43395 O43395 PRPF3 U4/U6 small nuclear ribonucleoprotein Prp3 1 0 GDDDEES(1)DEEAVK;GDDDEES(1)DEEAVK ; 206.45 4.83E-09 19347800 3754.9 3477.4 4008.2 4019.5 4685.9 4395.9 4017 3244.12 3242.75 3540.6 TRUE FALSE FALSE 3457.695703 3777.970961 4156.747418 4002.868374 4630.023703 3484.140788 4129.706209 4233.237254 2887.028438 3663.635586 0.943788109 1.031208173 1.13459631 1.092594577 1.26377845 0.951006372 1.127215333 1.155474434 0.788022818 1 11.83906029 -6.939090584 3.685431793 0.97371659 1.118374791 0.465479764 0.093716025 0.148746985 4.141920352 0.011600266 0.015304825 1.15E-07 6.939090584 0.144658201 GDDDEES(ph)DEEAVKK ddPTM_HeLa_Curcumin_4h_R1 4 GDDDEESDEEAVKK 14 1 O43395 O43395 PRPF3 U4/U6 small nuclear ribonucleoprotein Prp3 1 0 GDDDEES(1)DEEAVKK;GDDDEES(1)DEEAVKK;GDDDEES(1)DEEAVKK;GDDDEES(1)DEEAVKK ;;; 185.66 7.76E-05 332645500 10105 9923.3 10243.2 11365.6 13028.9 12215.3 11359.1 8914 9890.3 9747.7 TRUE FALSE FALSE 9305.178587 10781.02583 10622.822 11318.57216 12873.53888 9681.709085 11677.80577 11631.83756 8805.358834 10086.43185 0.922544139 1.068864193 1.053179376 1.122158195 1.276322397 0.959874535 1.157773725 1.153216295 0.872990465 1 13.30012828 -6.831657226 1.745158546 0.964277677 1.129728022 0.501190764 0.082517479 0.219868149 1.35975678 0.013323692 0.018754222 1.47E-07 6.831657226 0.165450345 GDDGIFDDNFIEER ddPTM_HeLa_Curcumin_4h_R1 4 GDDGIFDDNFIEER 14 0 O60493-4;O60493;O60493-2 O60493-4 SNX3 Sorting nexin-3 0 0 ;;; ;;; 322.7 3.46E-108 139991000 9414.3 8136.5 9346.3 8200.4 9943.4 12207.1 9269.8 8743.2 8265.2 8067.2 FALSE FALSE TRUE 8669.148221 8839.782804 9692.6821 8166.468918 9824.831449 9675.209858 9529.88564 11408.96143 7358.528239 8347.5346 1.038527977 1.058969292 1.161143088 0.978309083 1.176974031 1.159049986 1.141640747 1.366746229 0.881521143 1 13.02713445 -1 0.315776061 1.011389965 3.929989464 0.678694286 0.072569505 17.95439807 0.229191807 0.018739871 30.54527702 0.1 1 2.9185995 GDDLLPAGTEDYIHIR ddPTM_HeLa_Curcumin_4h_R1 1 GDDLLPAGTEDYIHIR 16 0 K7EM18;P41567;O60739 K7EM18 EIF1;EIF1B Eukaryotic translation initiation factor 1;Eukaryotic translation initiation factor 1b 0 0 86.539 0.0064975 2667000 3265.2 3007.6 3070.9 3442.7 3866.3 2717.2 2287.6 1935.9 3198.5 3299 FALSE FALSE TRUE 3006.755975 3267.563542 3184.710255 3428.45502 3820.196898 2153.622091 2351.783899 2526.146998 2847.632552 3413.640004 0.880806403 0.957208006 0.932936763 1.004339947 1.119097764 0.63088729 0.688937292 0.740015642 0.834192401 1 11.73709521 -5.247112805 24.99045541 0.957495144 0.686845777 0.732602282 0.076004752 304.9815147 531991.2827 0.010386486 0.026345227 5.66E-06 5.247112805 -0.270649367 GDDS(ph)DEEDLCISNK ddPTM_HeLa_Curcumin_4h_R1 1 GDDSDEEDLCISNK 14 0 H3BRG5;Q9Y3M8-5;Q9Y3M8-3;Q9Y3M8-4;Q9Y3M8-2;Q9Y3M8 H3BRG5 STARD13 StAR-related lipid transfer protein 13 1 0 GDDS(1)DEEDLCISNK 146.77 0.00059506 2133200 1074.4 925.19 1033.3 1075.9 1554.6 904.06 594 785.26 1053.7 985.15 TRUE FALSE FALSE 989.3601063 1005.159301 1071.595007 1071.448211 1536.06241 716.5477651 610.6660413 1024.682159 938.1117462 1019.383889 0.970547128 0.986045897 1.051218308 1.051074303 1.506853725 0.702922395 0.599054044 1.005197522 0.920273271 1 9.993481742 GDDWNDREWDR ddPTM_HeLa_Curcumin_4h_R1 1 GDDWNDREWDR 11 1 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9 Q9BXP5-5;C9JUL9 SRRT Serrate RNA effector molecule homolog 0 0 85.963 0.01871 25522000 1912.6 1391.3 1636.8 1675.7 1646.1 1875 1464.9 1433.5 1803.6 1796.1 FALSE FALSE TRUE 1761.215692 1511.557772 1697.461248 1668.766397 1626.471333 1486.103864 1506.001151 1870.567551 1605.749592 1858.514341 0.947647082 0.813315097 0.913343099 0.897903428 0.875145968 0.799619261 0.810325279 1.0064854 0.863996342 1 10.85993411 -7.490534705 3.60127557 0.978636975 0.870890787 0.074055534 0.068595287 0.16265446 4.225939806 0.010289061 0.011318043 3.23E-08 7.490534705 -0.107746188 GDEASEEGQNGSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 GDEASEEGQNGSSPK 15 0 E7EV99;E7ENY0;P35611-5;P35611-2;P35611-6;P35611-4;P35611;P35611-3;H0Y9H2 E7EV99 ADD1 Alpha-adducin 1 0 GDEASEEGQNGS(0.002)S(0.998)PK;GDEASEEGQNGS(0.022)S(0.978)PK;GDEASEEGQNGS(0.343)S(0.657)PK;GDEASEEGQNGS(0.016)S(0.984)PK ;;; 239.87 5.51E-29 250923500 18378 17255.5 17878.5 18251.9 19114.6 18032.6 15745.7 11581.6 15479.6 15091.5 TRUE FALSE FALSE 16923.36191 18746.98853 18541.09294 18176.37847 18886.67088 14292.43549 16187.48196 15112.77652 13781.52661 15615.9285 1.083724346 1.20050425 1.187319277 1.163963992 1.209449113 0.915247242 1.036600671 0.967779567 0.882530079 1 13.93073073 -5.237713437 24.97070848 1.083510311 0.979548322 0.244130737 0.100842676 1022.672315 1076324.033 0.013731912 0.034986333 5.78E-06 5.237713437 -0.103961989 GDEELDS(ph)LIK ddPTM_HeLa_Curcumin_4h_R1 1 GDEELDSLIK 10 0 A0A494C189;P0C0S5;Q71UI9-4;C9J0D1;Q71UI9-2;Q71UI9;C9J386;Q71UI9-3 A0A494C189;C9J0D1 H2AFZ;H2AFV Histone H2A.Z;Histone H2A.V;Histone H2A 1 0 GDEELDS(1)LIK 92.247 0.017723 1785100 1479.2 1126.2 1213.3 1366.7 1476.1 1543.2 1373.4 974.52 1448.4 1403.7 TRUE FALSE FALSE 1362.119759 1223.54371 1258.265965 1361.044958 1458.498472 1223.122925 1411.933908 1271.646662 1289.514144 1452.478471 0.937789982 0.842383371 0.866288892 0.937050005 1.00414464 0.842093669 0.972085946 0.875501212 0.887802587 1 10.50430106 -8.316518895 1.047063361 0.989911747 0.91039032 0 0.060841659 0.40980748 0.929345353 0.01578131 0.010534622 4.82E-09 8.316518895 -0.079521427 GDEELDSLIK ddPTM_HeLa_Curcumin_4h_R1 3 GDEELDSLIK 10 0 A0A494C189;P0C0S5;Q71UI9-4;C9J0D1;Q71UI9-2;Q71UI9;C9J386;Q71UI9-3 A0A494C189;C9J0D1 H2AFZ;H2AFV Histone H2A.Z;Histone H2A.V;Histone H2A 0 0 ;; ;; 211.52 5.48E-27 23644600 10584.5 8340.7 9802.2 10356.1 12042.6 14110.8 11677.3 9012.9 10763.1 8600.8 FALSE FALSE TRUE 9746.725656 9061.632943 10165.47815 10313.2492 11898.99986 11184.06102 12004.93361 11760.89172 9582.414858 8899.67716 1.095177441 1.018197939 1.14222999 1.158834081 1.337014776 1.256681655 1.348917876 1.321496444 1.076714884 1 13.11953729 -6.090516382 1.063924358 1.04116137 1.32916138 0.885444888 0.042436617 0.117330674 0.261907087 0.007857962 0.018225788 8.12E-07 6.090516382 0.28800001 GDEGIFEESFIEER ddPTM_HeLa_Curcumin_4h_R1 3 GDEGIFEESFIEER 14 0 A0A087X0R6;Q9UMY4-3;Q9UMY4;Q9UMY4-1 A0A087X0R6 SNX12 Sorting nexin-12 0 0 ;; ;; 234.79 5.58E-20 24786300 4015.35 3203.68 4056.35 3440.35 3695.42 5042.1 3847 3665.87 4088.38 3186.59 FALSE FALSE TRUE 3697.530811 3480.591824 4206.681899 3426.114743 3651.35453 3996.311624 3954.936466 4783.576887 3639.894943 3297.323765 1.121373294 1.05558085 1.275786728 1.039059245 1.107369124 1.211986419 1.199438317 1.450745279 1.103893703 1 11.68707984 -1 0.37357843 1.055059308 5.791794078 0.635649119 0.076498853 26.35730168 0.322478294 0.020589918 90.9848678 0.1 1 4.736734769 GDFCIQVGR ddPTM_HeLa_Curcumin_4h_R1 2 GDFCIQVGR 9 0 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;O60361;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase;Nucleoside diphosphate kinase A 0 0 ; ; 134.48 0.00036389 18573200 3892.1 3999.4 4114.4 3657.8 3958.4 6136.5 4675.9 4180.4 4447.4 3890.6 FALSE FALSE TRUE 3584.036178 4345.090315 4266.883283 3642.664993 3911.198665 4863.720727 4807.093169 5454.984716 3959.531347 4025.79806 0.890267252 1.079311543 1.059885076 0.90483053 0.971533745 1.208138276 1.194072106 1.355007041 0.983539484 1 11.97505909 -5.130905763 2.165110619 0.96239426 1.280152042 0.761102671 0.068648373 0.118441302 1.064382198 0.010994242 0.03732735 7.40E-06 5.130905763 0.317757782 GDFGPTLGLLRPAPEPEAEGSAVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 GDFGPTLGLLRPAPEPEAEGSAVKR 25 2 Q14814-4;Q14814;Q14814-6;Q14814-3;Q14814-5;Q14814-2 Q14814-4 MEF2D Myocyte-specific enhancer factor 2D 0 1 GDFGPTLGLLRPAPEPEAEGSAVK(1)R 99.414 1.07E-07 2430900 509.91 382.73 483.4 484.19 542.56 681.05 391.15 251.78 379.82 281.89 FALSE TRUE FALSE 469.5500854 415.8114758 501.3152292 482.1865501 536.0903264 539.792553 402.1246163 328.5465629 338.1546963 291.6856565 1.609781198 1.425546531 1.718683172 1.653103398 1.837904314 1.850596836 1.378623211 1.126372023 1.159312049 1 8.188270634 -9.183282289 0.680561068 0.948066197 1.597920508 0.452860467 0.214457515 0.589844983 0.434358284 0.223174272 0.047289119 6.56E-10 9.183282289 0.649854311 GDGPVQGIINFEQK ddPTM_HeLa_Curcumin_4h_R1 1 GDGPVQGIINFEQK 14 0 P00441 P00441 SOD1 Superoxide dismutase [Cu-Zn] 0 0 204.13 6.83E-19 925420 563.74 419.35 516.49 505.73 378.74 434.37 393.71 386.52 315.84 333.78 FALSE FALSE TRUE 519.1193841 455.5967454 535.6315738 503.6374233 374.2237729 344.2767656 404.756443 504.3681687 281.1931422 345.3788302 1.503043438 1.319121804 1.55085236 1.45821741 1.083516823 0.996809114 1.171920244 1.46033319 0.814158592 1 8.432035846 -3.319240913 14.33649738 1.261836446 1.208079319 0 0.245368121 0 0 0.032448323 0 0.000479467 3.319240913 -0.053757127 GDGVVLVAPPLR ddPTM_HeLa_Curcumin_4h_R1 2 GDGVVLVAPPLR 12 0 P62310 P62310 LSM3 U6 snRNA-associated Sm-like protein LSm3 0 0 ; ; 122.96 0.0008816 3072500 2017.35 1791.76 2195.3 2056.5 1981.12 2753.1 2133.7 2439.68 2064.91 2329.7 FALSE FALSE TRUE 1857.674619 1946.63175 2276.659749 2047.990748 1957.496438 2182.076026 2193.565879 3183.527201 1838.394539 2410.656902 0.770609296 0.807510911 0.944414673 0.849557126 0.812017851 0.905179009 0.909945284 1.320605682 0.762611443 1 11.23521062 -4.255757856 4.056031787 0.879903772 1.361318432 0.770503496 0.074644675 0.107958311 3.731284339 0.012587679 0.152657762 5.55E-05 4.255757856 0.48141466 GDLAFGAPGPRPPS(ph)PFDDPADDPEHK ddPTM_HeLa_Curcumin_4h_R1 2 GDLAFGAPGPRPPSPFDDPADDPEHK 26 1 Q7Z3Z5;Q93074-3;Q93074;Q93074-2 Q7Z3Z5 TNRC11;MED12 Mediator of RNA polymerase II transcription subunit 12 1 0 GDLAFGAPGPRPPS(1)PFDDPADDPEHK;GDLAFGAPGPRPPS(1)PFDDPADDPEHK ; 69.913 0.00022598 40762500 6082 6727 7089.3 6489.2 6833.1 7033.9 5809.4 4445 5708.1 6545.2 TRUE FALSE FALSE 5600.603282 7308.451905 7352.035694 6462.34941 6751.619745 5574.989852 5972.396129 5800.260038 5081.935711 6772.645213 0.826944732 1.079113356 1.085548624 0.954183957 0.996895531 0.823162838 0.881840985 0.85642461 0.750362015 1 12.72550371 -5.255937968 24.77009379 0.949059145 0.856612628 0.182870366 0.098285761 584.5160058 2631768.199 0.013693193 0.03384385 5.55E-06 5.255937968 -0.092446517 GDLGIEIPAEK ddPTM_HeLa_Curcumin_4h_R1 3 GDLGIEIPAEK 11 0 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BR70;P30613-2;P30613 P14618;P14618-2;P30613-2 PKM;PKLR Pyruvate kinase PKM;Pyruvate kinase;Pyruvate kinase PKLR 0 0 ;; ;; 169.65 1.94E-08 80540000 24283.9 20169.1 20324.5 20360.7 20367.1 29250.4 21900.9 20490.6 22300.8 18936.7 FALSE FALSE TRUE 22361.80369 21912.42713 21077.74385 20276.45282 20124.23563 23183.53732 22515.38031 26738.08961 19854.45803 19594.74892 1.141214097 1.118280577 1.075683283 1.034790132 1.027021868 1.183150518 1.149051739 1.364553827 1.013254016 1 14.25817947 -3.172798723 0.857564921 1.068766539 2.864075939 0.755844203 0.051324664 5.427890892 0.716413253 0.009808547 14.25650212 0.00067174 3.172798723 1.7953094 GDLPFVVPR ddPTM_HeLa_Curcumin_4h_R1 1 GDLPFVVPR 9 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 107.29 0.0045044 1803600 1194.2 1179.7 1086.6 1360.1 1000.4 1426.2 1107.5 1058.6 1584.9 1065.9 FALSE FALSE TRUE 1099.67781 1281.668011 1126.870352 1354.472267 988.4708834 1130.390043 1138.573469 1381.362267 1411.040435 1102.939946 0.997042327 1.16204696 1.021696926 1.228056225 0.896214601 1.024888116 1.032307764 1.25243652 1.279344756 1 10.10713852 -4.260774577 5.127828195 1.022552686 1.263026134 0.053925891 0.120316127 0.131784298 11.31610375 0.011795612 0.111570755 5.49E-05 4.260774577 0.240473448 GDLS(ph)DVEEEEEEEMDVDEATGAVK ddPTM_HeLa_Curcumin_4h_R1 2 GDLSDVEEEEEEEMDVDEATGAVK 24 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 0 GDLS(1)DVEEEEEEEMDVDEATGAVK;GDLS(1)DVEEEEEEEMDVDEATGAVK ; 126.99 5.74E-07 5804600 3551.3 2850.5 3007.3 3410.3 3561.6 3945.5 2886.5 2426 3990.4 3182.2 TRUE FALSE FALSE 3270.210858 3096.884518 3118.753183 3396.189082 3519.130246 3127.158825 2967.487421 3165.676232 3552.663103 3292.781213 0.993145504 0.940507224 0.94714862 1.031404415 1.068740988 0.949701369 0.90121002 0.961398899 1.078924737 1 11.68509094 -5.014771937 24.80834595 0.995880101 0.929842256 0.318976206 0.045550069 480.6233051 807174.7277 0.005303755 0.014110342 9.67E-06 5.014771937 -0.066037846 GDLS(ph)DVEEEEEEEMDVDEATGAVKK ddPTM_HeLa_Curcumin_4h_R1 7 GDLSDVEEEEEEEMDVDEATGAVKK 25 1 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 0 GDLS(1)DVEEEEEEEMDVDEATGAVKK;GDLS(1)DVEEEEEEEMDVDEATGAVKK;GDLS(1)DVEEEEEEEMDVDEATGAVKK;GDLS(1)DVEEEEEEEMDVDEATGAVKK;GDLS(1)DVEEEEEEEMDVDEATGAVKK;GDLS(0.999)DVEEEEEEEMDVDEAT(0.001)GAVKK;GDLS(1)DVEEEEEEEMDVDEATGAVKK ;;;;;; 209.29 9.12E-23 485436500 18629.12 13947.51 16286.34 16776.71 16036.58 19471.67 15521.21 13139.85 18264.92 16401.43 TRUE FALSE FALSE 17154.60549 15153.07062 16889.92609 16707.29242 15845.35426 15433.02615 15956.69338 17146.12978 16261.30397 16971.37847 1.010796237 0.892860332 0.995200603 0.984439328 0.933651576 0.909356077 0.940211981 1.010296824 0.95816047 1 14.05081613 -7.370930682 21.69066236 1.005099386 0.95229051 0.133585055 0.037908036 7.855363787 1545.619058 0.005811576 0.006645729 4.26E-08 7.370930682 -0.052808876 GDMEQNDSDNRR ddPTM_HeLa_Curcumin_4h_R1 2 GDMEQNDSDNRR 12 1 Q9UN86-2;Q9UN86 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 0 0 ; ; 194.48 3.37E-06 26701000 4982 4859.9 4428.3 4168 4436.1 5906.1 3662.7 3502.6 4297.2 4988.4 FALSE FALSE TRUE 4587.669443 5279.968101 4592.416694 4150.75392 4383.202405 4681.108285 3765.465504 4570.526616 3825.807911 5161.746529 0.888782395 1.022903405 0.889702094 0.804137494 0.849170408 0.906884571 0.729494461 0.885461266 0.741184769 1 12.33364358 -6.52851162 9.530330865 0.951918256 0.835195115 0.094995737 0.087031445 0.090333827 102.3396677 0.009517822 0.01368575 2.96E-07 6.52851162 -0.116723141 GDMS(ph)DEDDENEFFDAPEIITMPENLGHK ddPTM_HeLa_Curcumin_4h_R1 5 GDMSDEDDENEFFDAPEIITMPENLGHK 28 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 0 GDMS(1)DEDDENEFFDAPEIITMPENLGHK;GDMS(1)DEDDENEFFDAPEIITMPENLGHK;GDMS(1)DEDDENEFFDAPEIITMPENLGHK;GDMS(1)DEDDENEFFDAPEIITMPENLGHK;GDMS(0.999)DEDDENEFFDAPEIIT(0.001)MPENLGHK ;;;; 106.39 9.81E-10 116283100 14684.66 13034.6 14895.57 14249.97 15645.66 13218.5 9593.66 7326.86 12098.91 12794.62 TRUE FALSE FALSE 13522.35367 14161.25274 15447.61293 14191.0074 15459.09572 10476.8341 9862.83228 9560.785885 10771.68984 13239.23209 1.021385045 1.069643061 1.16680581 1.071890522 1.167673141 0.791347566 0.744970117 0.722155622 0.81361893 1 13.69253182 -5.134830227 5.580267721 1.040488937 0.74217935 0.67067403 0.094015093 0.076299196 3.147464243 0.00996088 0.026045853 7.33E-06 5.134830227 -0.298309587 GDMS(ph)DEDDENEFFDAPEIITMPENLGHKR ddPTM_HeLa_Curcumin_4h_R1 1 GDMSDEDDENEFFDAPEIITMPENLGHKR 29 1 P22059 P22059 OSBP Oxysterol-binding protein 1 1 0 GDMS(1)DEDDENEFFDAPEIITMPENLGHKR 66.409 7.18E-05 53299000 1095.2 968.6 977.04 1065.1 830.41 895 679.05 504.45 1441 1047.4 TRUE FALSE FALSE 1008.513764 1052.321468 1013.249962 1060.692898 820.5079031 709.3669113 698.1023154 658.2544828 1282.925905 1083.797072 0.930537451 0.970958028 0.934907455 0.978682196 0.757067835 0.654520048 0.644126408 0.607359532 1.183732581 1 10.08187894 -5.577020462 2.390084173 0.965798164 0.634271786 0.834174218 0.073327263 0.039855975 0.457313099 0.004693273 0.010987298 2.65E-06 5.577020462 -0.331526378 GDPESPWWEGR ddPTM_HeLa_Curcumin_4h_R1 2 GDPESPWWEGR 11 0 P52735-3;P52735-2;P52735 P52735-3 VAV2 Guanine nucleotide exchange factor VAV2 0 0 ; ; 169.65 0.0020722 9374600 2345.3 2030.03 2275.74 2118.05 2154.93 2348.05 1705.71 1463.86 2416.49 2258.6 FALSE FALSE TRUE 2159.66703 2205.496748 2360.080926 2109.28607 2129.233867 1861.037962 1753.567632 1910.184175 2151.407093 2337.086182 0.924085319 0.943695087 1.009839066 0.902528151 0.911063479 0.796306947 0.750322194 0.817335788 0.92055103 1 11.19049522 -5.432873483 1.616537653 0.963305506 0.776545145 0.806079959 0.035512874 0.120517966 0.60722033 0.005767525 0.017571013 3.69E-06 5.432873483 -0.18676036 GDPEWS(ph)SETDALVGSR ddPTM_HeLa_Curcumin_4h_R1 1 GDPEWSSETDALVGSR 16 0 Q7Z7N9 Q7Z7N9 TMEM179B Transmembrane protein 179B 1 0 GDPEWS(0.935)S(0.057)ET(0.008)DALVGSR 152.94 0.00033116 2552600 451.88 484.4 689.47 730.01 467.84 600.42 515.81 321.36 782.18 867.79 TRUE FALSE FALSE 416.1132212 526.2693776 715.0223647 726.989412 462.2613136 475.8861239 530.2822404 419.3411846 696.3768109 897.9456379 0.463405805 0.586081557 0.796286918 0.809614058 0.514798774 0.529972087 0.590550494 0.467000637 0.775522238 1 9.810484296 -9.414601599 1.067656758 1.006961001 0.591552521 0.405012076 0.1321774 0.298227714 0.591650208 0.095449519 0.022565732 3.85E-10 9.414601599 -0.41540848 GDPGPQGIS(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 GDPGPQGISGK 11 0 P12107-4;P12107-3;P12107;P12107-2 P12107-4 COL11A1 Collagen alpha-1(XI) chain 1 0 GDPGPQGIS(1)GK 87.568 0.020014 40696000 2991 3344.5 3712.2 2942.6 2344.6 3529.7 2902.2 2036.5 3378.7 3959.1 TRUE FALSE FALSE 2754.259194 3633.583677 3849.777398 2930.424301 2316.642176 2797.600432 2983.627921 2657.419475 3008.065063 4096.67843 0.672315204 0.886958481 0.93973141 0.715317141 0.565492805 0.682894808 0.728304155 0.64867661 0.734269266 1 12.00023894 -6.073025308 6.073641059 0.851146127 0.660560544 0.473747708 0.095547214 0.205161657 13.42952694 0.019546158 0.032814218 8.45E-07 6.073025308 -0.190585582 GDPGS(ph)SPAGPR ddPTM_HeLa_Curcumin_4h_R1 1 GDPGSSPAGPR 11 0 H3BRW8;Q9P1Z2-4;Q9P1Z2-2;Q9P1Z2-3;Q9P1Z2 H3BRW8 CALCOCO1 Calcium-binding and coiled-coil domain-containing protein 1 1 0 GDPGS(0.5)S(0.5)PAGPR 91.123 0.016507 27016000 3967.2 3278.2 3102.7 3048.9 3106.2 3415.7 2304.6 1669 3735.5 3117.6 TRUE FALSE FALSE 3653.191934 3561.553001 3217.688791 3036.28446 3069.160594 2707.245317 2369.260873 2177.870417 3325.724996 3225.936368 1.132443891 1.104036966 0.997443354 0.941210276 0.951401467 0.83921225 0.734441292 0.67511264 1.030933229 1 11.65550227 -5.068519639 0.759760905 1.064907923 0.618341176 0.909409725 0.042758204 0.310236231 0.234662044 0.010169299 0.09329055 8.54E-06 5.068519639 -0.446566746 GDPPRLS(ph)PDPVAGSAVSQELR ddPTM_HeLa_Curcumin_4h_R1 1 GDPPRLSPDPVAGSAVSQELR 21 1 Q9BUR4;E9PMG4;E9PMR3 Q9BUR4 WRAP53 Telomerase Cajal body protein 1 1 0 GDPPRLS(0.999)PDPVAGSAVSQELR 54.511 0.0082549 107180000 1899.1 1598.3 2004.5 1924 2019.6 1632.3 1004.8 1056.3 1758.5 1733.5 TRUE FALSE FALSE 1748.784231 1736.44993 2078.788533 1916.038998 1995.517589 1293.74258 1032.991984 1378.361007 1565.59695 1793.738996 0.974937956 0.968061649 1.158913609 1.068181604 1.112490498 0.721254644 0.575887566 0.768428969 0.872812016 1 10.80875427 -5.169344476 5.511914278 1.012577597 0.668930787 0.75166454 0.08786607 0.07399859 3.49333909 0.011117913 0.028996457 6.77E-06 5.169344476 -0.34364681 GDQCCYS(ph)HSPPTPR ddPTM_HeLa_Curcumin_4h_R1 1 GDQCCYSHSPPTPR 14 0 Q9NXH9-2;Q9NXH9 Q9NXH9-2 TRMT1 tRNA (guanine(26)-N(2))-dimethyltransferase 1 0 GDQCCYS(0.44)HS(0.44)PPT(0.119)PR 73.918 0.012862 67982000 1347.6 1389.7 1404.4 1242.6 875.23 1366.2 1300.5 807.13 1305.6 1794.7 TRUE FALSE FALSE 1240.936038 1509.819476 1456.448299 1237.45845 864.7934539 1082.83472 1336.98853 1053.220221 1162.378946 1857.065691 0.668224093 0.813013499 0.784273979 0.666351468 0.465677363 0.583089077 0.719946815 0.567142146 0.625922363 1 10.85880913 -13.52287875 0.16484539 2.396297487 0.552989965 0 0.146017975 25.75649744 0.280325231 11.5463245 0.165432133 3.00E-14 13.52287875 -1.843307522 GDQCCYSHS(ph)PPTPR ddPTM_HeLa_Curcumin_4h_R1 2 GDQCCYSHSPPTPR 14 0 Q9NXH9-2;Q9NXH9 Q9NXH9-2 TRMT1 tRNA (guanine(26)-N(2))-dimethyltransferase 1 0 GDQCCYS(0.002)HS(0.992)PPT(0.006)PR;GDQCCYS(0.012)HS(0.97)PPT(0.018)PR ; 89.507 0.0049259 64070700 1877.35 1947.57 1906.55 2158.5 1661.64 2496.55 1289.32 1045.88 2253.32 1991.48 TRUE FALSE FALSE 1728.755767 2115.909273 1977.20842 2149.568699 1641.826028 1978.737388 1325.494849 1364.763997 2006.136434 2060.683782 0.838923362 1.026799595 0.959491426 1.043133701 0.796738463 0.960233397 0.643230592 0.66228696 0.973529491 1 11.00890742 -4.759330872 24.99988646 0.933678105 0.652758665 0.713298278 0.074781614 23.92427715 283640.8725 0.011476397 0.039089214 1.74E-05 4.759330872 -0.28091944 GDQCCYSHSPPT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 GDQCCYSHSPPTPR 14 0 Q9NXH9-2;Q9NXH9 Q9NXH9-2 TRMT1 tRNA (guanine(26)-N(2))-dimethyltransferase 1 0 GDQCCYSHS(0.004)PPT(0.996)PR;GDQCCYSHSPPT(1)PR;GDQCCYSHS(0.003)PPT(0.997)PR;GDQCCYSHSPPT(1)PR ;;; 105.5 0.0034727 28284700 3934.78 4066.85 4616.76 4309.33 3939.31 6339.7 6101.5 6340.14 4926.61 4728.4 TRUE FALSE FALSE 3623.338011 4418.370392 4787.861187 4291.499134 3892.336301 5024.774757 6272.691669 8273.2195 4386.173209 4892.711548 0.740558272 0.903051478 0.978570091 0.877120814 0.795537661 1.026991824 1.282048125 1.690927294 0.896470835 1 12.25641852 -4.440463486 1.518158036 0.879288351 1.847579293 0.918937759 0.075263315 0.20606948 0.559951785 0.015214833 0.26794797 3.63E-05 4.440463486 0.968290942 GDQPAASGDS(ph)DDDEPPPLPR ddPTM_HeLa_Curcumin_4h_R1 2 GDQPAASGDSDDDEPPPLPR 20 0 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 0 GDQPAAS(0.012)GDS(0.988)DDDEPPPLPR;GDQPAAS(0.499)GDS(0.501)DDDEPPPLPR ; 260.15 1.29E-104 0 1350.34 1360.6 1190.56 1340.78 1585.79 1670.86 1102.63 1066.43 1536.14 1097.09 TRUE FALSE FALSE 1243.459164 1478.204201 1234.683201 1335.232208 1566.88049 1324.304802 1133.56683 1391.579598 1367.629285 1135.213796 1.095352407 1.302137277 1.087621737 1.176194486 1.380251452 1.166568629 0.998549202 1.225830414 1.204732792 1 10.14874831 -7.859068801 1.219981236 1.023683546 1.185416945 0.001518907 0.116658635 0.350943196 1.093962853 0.024553517 0.021989597 1.38E-08 7.859068801 0.161733398 GDQVLNFS(ph)DAEDLIDDSK ddPTM_HeLa_Curcumin_4h_R1 1 GDQVLNFSDAEDLIDDSK 18 0 F8W126;Q96EZ8-3;Q96EZ8;Q96EZ8-2;Q96EZ8-4 F8W126 MCRS1 Microspherule protein 1 1 0 GDQVLNFS(1)DAEDLIDDSK 118.37 0.00019084 3928200 2477.8 2122.5 2119.4 2870.6 2959.5 2743.7 2466.5 1213.9 2955.8 2230 TRUE FALSE FALSE 2281.679515 2305.959442 2197.946828 2858.722218 2924.209895 2174.625692 2535.703352 1584.012522 2631.556135 2307.492334 0.988813476 0.999335689 0.952526167 1.238886984 1.267267437 0.942419466 1.098900011 0.686464912 1.140439817 1 11.17211014 -4.254027905 24.5634667 1.02828476 0.686464703 0.463101501 0.116335537 518.7857378 1719330.166 0.01592089 0.221235396 5.57E-05 4.254027905 -0.341820057 GDRS(ph)PEPGQTWTR ddPTM_HeLa_Curcumin_4h_R1 3 GDRSPEPGQTWTR 13 1 Q09666;E9PKR9;E9PLK4;E9PJZ0;E9PJC6;Q09666-2 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GDRS(0.999)PEPGQT(0.001)WTR;GDRS(1)PEPGQTWTR;GDRS(1)PEPGQTWTR ;; 90.259 0.0053334 228279000 3460.07 3117.68 2959.77 3437.71 3219.22 3138.93 2312.31 3875.65 4378.09 3336.44 TRUE FALSE FALSE 3186.201808 3387.158367 3069.46168 3423.485667 3180.832904 2487.880535 2377.187195 5057.317844 3897.82448 3452.381042 0.92289981 0.981107915 0.889085429 0.991630305 0.921344679 0.720627447 0.688564549 1.464878234 1.129024993 1 11.75337599 -9.363657234 0.640864137 1.011157434 0.929135381 0.024940446 0.203376993 5.404236316 3.105425536 0.259645289 0.040938179 4.33E-10 9.363657234 -0.082022054 GDRSEDFGVNEDLADSDAR ddPTM_HeLa_Curcumin_4h_R1 3 GDRSEDFGVNEDLADSDAR 19 1 P04083 P04083 ANXA1 Annexin A1 0 0 ;; ;; 346.89 1.65E-154 371517000 7256 6168.7 5572.3 6385.1 5773.1 7783.9 5216.4 5534.9 7994.3 6481.4 FALSE FALSE TRUE 6681.679944 6701.894941 5778.81434 6358.680148 5704.259553 6169.431397 5362.758145 7222.46553 7117.345291 6706.628168 0.996280065 0.999294246 0.861657184 0.948118785 0.850540601 0.919900618 0.799620616 1.076914561 1.061240479 1 12.7113719 -6.778095822 24.53663162 0.998273114 0.9040199 0.327521716 0.071844422 158.3169876 233216.364 0.009802878 0.012904133 1.67E-07 6.778095822 -0.094253214 GDS(ph)ES(ph)EEDEDLEVPVPSR ddPTM_HeLa_Curcumin_4h_R1 2 GDSESEEDEDLEVPVPSR 18 0 P13861-2;P13861 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 2 0 GDS(0.722)ES(0.951)EEDEDLEVPVPS(0.327)R;GDS(1)ES(1)EEDEDLEVPVPSR ; 222.11 4.72E-17 58359000 4906.6 3824.99 4510.6 4311.8 5339.7 5118.1 4189.7 3358.7 3878.6 3692.3 TRUE FALSE FALSE 4518.237433 4155.605092 4677.766804 4293.958914 5276.027565 4056.548367 4307.251706 4382.752168 3453.127284 3820.60715 1.182596706 1.08768186 1.224351685 1.123894383 1.380939562 1.061754901 1.127373618 1.147134996 0.90381637 1 11.89958621 -9.31311672 0.658524521 0.977160765 1.170811518 0.460003344 0.089734992 0.878913068 0.556124155 0.100239392 0.017336968 4.86E-10 9.31311672 0.193650753 GDS(ph)ES(ph)EEDEQDSEEVR ddPTM_HeLa_Curcumin_4h_R1 1 GDSESEEDEQDSEEVR 16 0 Q9NZ63 Q9NZ63 C9orf78 Uncharacterized protein C9orf78 2 0 GDS(0.958)ES(0.715)EEDEQDS(0.327)EEVR 114.06 0.0031516 6192500 1867.9 1582.3 1465.9 1408.8 1988.3 1919.9 1564.8 1718.8 1387.9 1312.3 TRUE FALSE FALSE 1720.053744 1719.066961 1520.227544 1402.970759 1964.590821 1521.691098 1608.704077 2242.854208 1235.650842 1357.902327 1.266699165 1.265972469 1.119541158 1.033189745 1.446783603 1.120618963 1.18469793 1.651705106 0.90997034 1 10.407164 -1.000045596 0.02794257 6.68E-08 2.976698934 0.396666623 0.162689262 1336.021896 2.895589267 102.1051411 231.033158 0.099989502 1.000045596 2.976698867 GDS(ph)ESEEDEQDS(ph)EEVR ddPTM_HeLa_Curcumin_4h_R1 1 GDSESEEDEQDSEEVR 16 0 Q9NZ63 Q9NZ63 C9orf78 Uncharacterized protein C9orf78 2 0 GDS(0.999)ES(0.262)EEDEQDS(0.739)EEVR 154.52 0.00075622 9874900 3481.6 2809.4 2847 3124 3465.6 3872.8 2839.5 2926.7 3313.6 2959.4 TRUE FALSE FALSE 3206.027686 3052.232018 2952.512324 3111.073716 3424.274983 3069.537625 2919.168728 3819.037357 2950.10637 3062.23893 1.046955434 0.996732158 0.96416785 1.015947412 1.118225933 1.00238345 0.953279217 1.247138922 0.963382165 1 11.58037114 -4.251260764 24.90532992 1.018247711 1.247139055 0.697572495 0.046934435 578.2348645 1414812.847 0.006098208 0.112372121 5.61E-05 4.251260764 0.228891344 GDS(ph)ETDLEALFNAVMNPK ddPTM_HeLa_Curcumin_4h_R1 2 GDSETDLEALFNAVMNPK 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 0 GDS(0.998)ET(0.002)DLEALFNAVMNPK;GDS(0.998)ET(0.002)DLEALFNAVMNPK ; 403.05 1.54E-276 282540000 3574 2813.5 3254.4 3023.9 3164.6 2990 2823.7 1722.34 3191.5 2869.1 TRUE FALSE FALSE 3291.114129 3056.686403 3375.010927 3011.387903 3126.864212 2369.840296 2902.925422 2247.473537 2841.400435 2968.801011 1.108566764 1.029602992 1.136826252 1.014344812 1.053241426 0.798248278 0.977810709 0.75703071 0.957086859 1 11.53566468 -5.272711897 24.59220558 1.054558126 0.857707982 0.607330034 0.072456785 254.6675084 555584.6475 0.009384213 0.021166188 5.34E-06 5.272711897 -0.196850144 GDS(ph)LILEHQWELEK ddPTM_HeLa_Curcumin_4h_R1 2 GDSLILEHQWELEK 14 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4;A0A0U1RQL3 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 0 GDS(1)LILEHQWELEK;GDS(1)LILEHQWELEK ; 126.07 0.00060643 21684200 6314.1 5471.6 6736.5 6527.4 7041.7 7960.2 6429.8 6096.6 5903.2 5766.1 TRUE FALSE FALSE 5814.332322 5944.540723 6986.160616 6500.391348 6957.732327 6309.16479 6610.202883 7955.425275 5255.633729 5966.471546 0.974500972 0.996324323 1.170903198 1.089486692 1.166138525 1.0574365 1.107891462 1.333355102 0.880861274 1 12.54266229 -6.769363508 23.87662534 0.988249733 1.145299441 0.583077857 0.077854767 54.86576551 165318.9054 0.010687675 0.014197774 1.70E-07 6.769363508 0.157049708 GDS(ph)LKEPTSIAESSR ddPTM_HeLa_Curcumin_4h_R1 1 GDSLKEPTSIAESSR 15 1 Q9C0B5;Q9C0B5-2;H0YEF4 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5;Palmitoyltransferase 1 0 GDS(1)LKEPTSIAESSR 107.73 0.0028297 0 1363.3 1029.5 1133.1 1792 1447.8 2119 1250 770.95 2225.3 1173.9 TRUE FALSE FALSE 1255.393366 1118.485393 1175.093683 1784.585179 1430.535931 1679.495514 1285.071636 1006.009106 1981.190157 1214.692938 1.033506763 0.920796819 0.967399782 1.469165683 1.177693462 1.382650267 1.057939497 0.828200342 1.631021385 1 10.24637595 GDS(ph)PKIDLAGSSLSGILDK ddPTM_HeLa_Curcumin_4h_R1 1 GDSPKIDLAGSSLSGILDK 19 1 Q5JPT2;Q96B97-2;Q96B97;Q96B97-3 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 0 GDS(0.982)PKIDLAGS(0.01)S(0.005)LS(0.003)GILDK 50.432 0.018668 15990000 905.36 819.02 870.85 694.2 1018.4 1231.1 1253.3 870.76 873.45 928.19 TRUE FALSE FALSE 833.6998007 889.8124393 903.1244671 691.3275843 1006.256245 975.7559826 1288.464225 1136.250716 777.6347203 960.4445334 0.868035344 0.926458956 0.940319233 0.719799593 1.047698446 1.015942044 1.341529032 1.183046679 0.809661249 1 9.907558489 -4.975578039 2.378409487 0.924701913 1.263582972 0.664547387 0.098907622 0.131146346 1.455099751 0.013398055 0.050701961 1.06E-05 4.975578039 0.33888106 GDS(ph)PKIDLAGSSLSGILDKDLSDR ddPTM_HeLa_Curcumin_4h_R1 1 GDSPKIDLAGSSLSGILDKDLSDR 24 2 Q5JPT2;Q96B97-2;Q96B97;Q96B97-3 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 0 GDS(1)PKIDLAGSSLSGILDKDLSDR 65.416 0.00055859 28235000 2295.4 1878.8 2037.6 1876.4 1936.6 4328.6 4236.2 2321.8 2297.4 1773.7 TRUE FALSE FALSE 2113.716668 2041.1951 2113.115248 1868.635954 1913.50731 3430.799567 4355.056371 3029.706132 2045.380968 1835.335943 1.151678349 1.112164292 1.15135066 1.018143823 1.042592402 1.869303317 2.372893305 1.650763798 1.114445002 1 10.84182845 -5.208081077 4.457169312 1.075753554 2.030135913 0.847332553 0.171403564 0.050377555 2.144007798 0.02197736 0.057630803 6.19E-06 5.208081077 0.954382359 GDSIEEILADS(ph)EDEEDNEEEERSR ddPTM_HeLa_Curcumin_4h_R1 1 GDSIEEILADSEDEEDNEEEERSR 24 1 Q5JTH9-2;Q5JTH9-3;Q5JTH9 Q5JTH9-2 RRP12 RRP12-like protein 1 0 GDSIEEILADS(0.996)EDEEDNEEEERS(0.004)R 70.761 0.0013404 0 1144 667.5 885.38 982.69 790.99 1074.3 904.79 688.77 1470 1333.2 TRUE FALSE FALSE 1053.451193 725.1957257 918.1929617 978.6238892 781.5579609 851.4780701 930.1759723 898.7728023 1308.744678 1379.528601 0.763631281 0.525683719 0.665584578 0.709390069 0.566539875 0.617223934 0.674270886 0.65150719 0.948689775 1 10.42995965 -8.271053712 0.675843374 0.985454978 0.62846774 0.824055176 0.061322686 0.182083774 0.180765319 0.029288564 0.016075102 5.36E-09 8.271053712 -0.356987238 GDSK(ac)NAK(ac)K(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 GDSKNAKKK 9 3 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 0 3 GDSK(1)NAK(1)K(1)K 139.43 2.46E-05 12868000 4741.1 3660.4 4340.3 3879.9 4358.6 4613.4 3084.2 1415.4 3862.1 3096.1 FALSE TRUE FALSE 4365.836932 3976.788666 4501.155336 3863.846002 4306.626542 3656.528836 3170.734351 1846.948944 3438.437292 3203.689245 1.362752939 1.241315359 1.404991244 1.206061421 1.344270999 1.141349412 0.989713455 0.576506897 1.073274288 1 11.6455185 -4.297160346 1.775098013 1.211227181 0.394656606 0.731279091 0.120461572 0.42798449 1.407823996 0.022468947 0.57097806 5.04E-05 4.297160346 -0.816570575 GDTGGEDTAAPGR ddPTM_HeLa_Curcumin_4h_R1 1 GDTGGEDTAAPGR 13 0 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 0 0 192.44 2.76E-13 1333400 743.44 514.41 838.04 659.6 657.87 889.68 749.18 557.92 713.3 622.87 FALSE FALSE TRUE 684.5959395 558.8733082 869.0984996 656.87075 650.0253299 705.1503392 770.1999745 728.0272397 635.0527746 644.5146861 1.06218827 0.86712269 1.348454144 1.019171113 1.008550067 1.094079552 1.195007641 1.129574322 0.985319324 1 9.332069422 -1.000000009 0.132534442 0.977325379 1.576691127 0.157736663 0.114969563 117.4971761 1.044910838 0.354021654 13.25690114 0.099999998 1.000000009 0.599365748 GDTPGHAT(ph)PGHGGATSSAR ddPTM_HeLa_Curcumin_4h_R1 2 GDTPGHATPGHGGATSSAR 19 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 GDT(0.016)PGHAT(0.981)PGHGGAT(0.001)S(0.001)S(0.001)AR;GDT(0.001)PGHAT(0.998)PGHGGATS(0.001)SAR ; 110.4 0.00045531 7389500 1296.72 1048.94 1127.65 1097.02 2418.04 3115.2 1862.97 1122.56 1700.91 986.4 TRUE FALSE FALSE 1194.083244 1139.6057 1169.441701 1092.480822 2389.206452 2469.072404 1915.239924 1464.823376 1514.324428 1020.677327 1.169892984 1.11651907 1.145750641 1.070348869 2.340804866 2.419052858 1.876440158 1.435148345 1.483646584 1 9.995311134 -5.772229645 24.99401418 1.089962403 2.036416541 0.68178829 0.282816326 74.88482204 173459.5181 0.038654344 0.070573306 1.69E-06 5.772229645 0.946454138 GDTVSAS(ph)PCSAPLAR ddPTM_HeLa_Curcumin_4h_R1 3 GDTVSASPCSAPLAR 15 0 Q15477 Q15477 SKIV2L Helicase SKI2W 1 0 GDTVS(0.015)AS(0.906)PCS(0.08)APLAR;GDTVS(0.001)AS(0.986)PCS(0.013)APLAR;GDTVS(0.002)AS(0.623)PCS(0.375)APLAR ;; 245.4 2.40E-29 284207000 7502.2 6426.6 6965.2 7572.3 7586.6 8529 6260.9 4590.9 7155.7 6059.5 TRUE FALSE FALSE 6908.392954 6982.086668 7223.336439 7540.967829 7496.13475 6759.989258 6436.564004 5990.644276 6370.737613 6270.067174 1.101805254 1.113558511 1.152034937 1.202693308 1.195542973 1.078136656 1.026554234 0.955435422 1.016055719 1 12.61426518 -3.086644729 13.78028477 1.074576302 1.099346955 0 0.080503043 0 0 0.011980518 0 0.000819135 3.086644729 0.024770653 GDVDVSLPK ddPTM_HeLa_Curcumin_4h_R1 2 GDVDVSLPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 130.75 0.00057954 5776100 9041.9 7825.4 8794.6 9066.6 8811.3 10368.6 8429 8882.2 9000.7 7208.6 FALSE FALSE TRUE 8326.224074 8501.792707 9120.535613 9029.084812 8706.231002 8218.035482 8665.495055 11590.34189 8013.345729 7459.098313 1.116250748 1.139788263 1.222739697 1.210479395 1.167196173 1.101746503 1.16173493 1.553852946 1.074304881 1 12.86478553 -1 0.17844702 1.000463617 2.50090564 0.520982243 0.097419606 33.86326293 0.365872434 0.12760766 13.82654281 0.1 1 1.500442024 GDVEGSQS(ph)QDEGEGSGESER ddPTM_HeLa_Curcumin_4h_R1 2 GDVEGSQSQDEGEGSGESER 20 0 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1 0 GDVEGS(0.001)QS(0.999)QDEGEGSGESER;GDVEGS(0.001)QS(0.999)QDEGEGSGESER ; 206.8 6.73E-14 12113000 2417.93 1891.19 2132.1 2055.89 2036.58 2625.3 2016.69 1649.03 2202.5 2181.1 TRUE FALSE FALSE 2226.548289 2054.656037 2211.117502 2047.383272 2012.295114 2080.783187 2073.272894 2151.811656 1960.89126 2256.893063 0.986554625 0.910391401 0.979717443 0.907168933 0.891621826 0.921968002 0.918640288 0.953439794 0.868845446 1 11.14012235 -7.243579873 1.085338041 0.997016824 0.920962141 0 0.047561412 0.203368859 0.467470142 0.005064451 0.006071041 5.71E-08 7.243579873 -0.076054683 GDVTAEEAAGAS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 8 GDVTAEEAAGASPAK 15 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 0 GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK;GDVTAEEAAGAS(1)PAK ;;;;;;; 207.55 1.17E-09 1435751000 32616.6 29255.4 30958.2 31416.3 33607.6 36975.5 29749.2 22046.3 31535 26630.5 TRUE FALSE FALSE 30034.96169 31784.10642 32105.53813 31286.30767 33206.85132 29306.3645 30583.88249 28768.11538 28075.6894 27555.90789 1.089964512 1.153440726 1.165105438 1.13537568 1.205071938 1.063523823 1.10988477 1.043990838 1.018862797 1 14.75007404 -8.389651057 0.841376631 1.009815299 1.125618475 0.488362533 0.045584437 0.326843361 0.485088605 0.018191099 0.010322345 4.08E-09 8.389651057 0.115803176 GDVTAEEAAGAS(ph)PAKANGQENGHVK ddPTM_HeLa_Curcumin_4h_R1 2 GDVTAEEAAGASPAKANGQENGHVK 25 1 P49006 P49006 MARCKSL1 MARCKS-related protein 1 0 GDVTAEEAAGAS(1)PAKANGQENGHVK;GDVTAEEAAGAS(1)PAKANGQENGHVK ; 97.509 3.86E-06 124076000 8012.5 5705.5 6047.4 6901.2 5494.2 7576.3 4936.9 3301.3 8624.3 7755.9 TRUE FALSE FALSE 7378.30217 6198.657997 6271.521964 6872.644663 5428.685253 6004.889978 5075.416127 4307.851173 7678.235867 8025.416948 0.919366834 0.772378312 0.781457463 0.856359826 0.676436538 0.748234019 0.63241775 0.536775996 0.956739808 1 12.97036063 -3.575881241 0.18752293 1.050172715 2.34E-12 0.8654321 0.051485305 4.597421376 0.120864929 0.0700484 1.183334081 0.000265533 3.575881241 -1.050172715 GDYDAFFEAR ddPTM_HeLa_Curcumin_4h_R1 2 GDYDAFFEAR 10 0 O75368 O75368 SH3BGRL SH3 domain-binding glutamic acid-rich-like protein 0 0 ; ; 154.85 0.005489 53726200 7492 6155 6930.6 6830 7477.8 8617.6 6957.8 7309.3 6706.5 6134.7 FALSE FALSE TRUE 6899.000294 6687.010774 7187.454133 6801.73927 7388.632119 6830.21262 7153.017142 9537.871922 5970.813729 6347.880368 1.08681952 1.053424196 1.132260489 1.071497709 1.163952641 1.075983198 1.12683553 1.502528619 0.940599599 1 12.63205922 -1.56607521 1.088602054 1.057628712 199.9977923 0.825610434 0.059740453 191.3137694 0.652686491 0.008306084 94498.58983 0.027159689 1.56607521 198.9401636 GDYPLEAVR ddPTM_HeLa_Curcumin_4h_R1 2 GDYPLEAVR 9 0 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BR70 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 136.27 0.00026045 34707000 8299.3 5621.6 7703.9 6513.5 7524.4 8877 6849.6 7024 6145.3 6025.6 FALSE FALSE TRUE 7642.401648 6107.506055 7989.413311 6486.548863 7434.676444 7035.810136 7041.781341 9165.585265 5471.175965 6234.989151 1.225728139 0.979553598 1.281383675 1.040346455 1.19241209 1.128439836 1.129397529 1.470024252 0.877495667 1 12.60617133 -13.52287875 0.028864925 6.47E-11 1.897142636 0.357194131 0.12998875 1393.608147 3.23204739 158.8787908 70.37457389 3.00E-14 13.52287875 1.897142636 GEAAAERPGEAAVAS(ph)SPSK ddPTM_HeLa_Curcumin_4h_R1 1 GEAAAERPGEAAVASSPSK 19 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 GEAAAERPGEAAVAS(0.97)S(0.03)PSK 123.54 0.0017684 218520000 4623.3 3926.7 4983.6 4039 5623.3 4843.3 4987.9 2681.3 3980.2 3211.5 TRUE FALSE FALSE 4257.360927 4266.106451 5168.2966 4022.287688 5556.24582 3838.744985 5127.84705 3498.816027 3543.582018 3323.099386 1.281141619 1.283773356 1.555263927 1.210402465 1.672007116 1.15517008 1.543091691 1.052877335 1.066348492 1 11.69831373 -8.585437282 0.623638266 0.999458441 1.368662306 0.313878651 0.184232886 0.582659051 0.454641599 0.105137883 0.040870458 2.60E-09 8.585437282 0.369203865 GEAAAERPGEAAVASSPS(ph)K ddPTM_HeLa_Curcumin_4h_R1 3 GEAAAERPGEAAVASSPSK 19 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 GEAAAERPGEAAVAS(0.08)S(0.2)PS(0.72)K;GEAAAERPGEAAVAS(0.013)S(0.031)PS(0.956)K;GEAAAERPGEAAVAS(0.006)S(0.02)PS(0.975)K ;; 123.17 8.32E-05 4134483000 13612.6 13302.1 14177.8 13404.7 17375.4 16311.9 13824.1 8000.8 12250.3 10278.1 TRUE FALSE FALSE 12535.14835 14451.87425 14703.24174 13349.2349 17168.2097 12928.62807 14211.96704 10440.20709 10906.47274 10635.26321 1.178640161 1.358863807 1.382499093 1.255186133 1.614272197 1.215637809 1.336306094 0.981659493 1.02550097 1 13.37656812 -7.958387241 0.967152522 1.035576903 1.315649094 0.354312851 0.152136522 0.350749911 0.698479498 0.041207753 0.033242633 1.10E-08 7.958387241 0.280072191 GEAAAERPGEAAVASSPSK ddPTM_HeLa_Curcumin_4h_R1 1 GEAAAERPGEAAVASSPSK 19 1 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 0 0 116.73 1.24E-05 6851500 2784.2 2815.9 2598.3 2650.5 2790.1 3782.6 2569.3 2035.2 2671.2 2474 FALSE FALSE TRUE 2563.827632 3059.293849 2694.595284 2639.532933 2756.82988 2998.046121 2641.387643 2655.723111 2378.176043 2559.971316 1.00150639 1.19505005 1.052588077 1.031079105 1.076898738 1.171124888 1.031803609 1.037403464 0.928985426 1 11.32191193 -7.444066968 24.99987311 1.000662428 1.083853486 0.404093924 0.058135041 87.93137146 27892.32499 0.008872801 0.010146391 3.60E-08 7.444066968 0.083191057 GEAEQS(ph)EEEADEEDKAEDAR ddPTM_HeLa_Curcumin_4h_R1 1 GEAEQSEEEADEEDKAEDAR 20 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 GEAEQS(1)EEEADEEDKAEDAR 73.994 0.0021096 12456000 1895.7 1706.5 2263.2 1815.2 2611.7 1946.6 1556.6 1529.2 1525.2 1470.6 TRUE FALSE FALSE 1745.653345 1854.002256 2347.076183 1807.689183 2580.557183 1542.853217 1600.274007 1995.44604 1357.889376 1521.703241 1.147170682 1.218373075 1.542400726 1.187938052 1.695834716 1.013898884 1.051633435 1.31132404 0.89234835 1 10.57147132 -7.685183038 1.261900619 1.042416629 1.289478254 0.289370719 0.201204553 0.431617445 1.420222265 0.043657867 0.042751562 2.06E-08 7.685183038 0.247061625 GEAERGS(ph)GGS(ph)S(ph)GDELREDDEPVK ddPTM_HeLa_Curcumin_4h_R1 1 GEAERGSGGSSGDELREDDEPVK 23 2 Q7Z4V5-2;Q7Z4V5;Q7Z4V5-4;Q7Z4V5-3;A0A087WT54 Q7Z4V5-2 HDGFRP2 Hepatoma-derived growth factor-related protein 2 3 0 GEAERGS(1)GGS(1)S(1)GDELREDDEPVK 50.916 0.019551 42430000 3511.5 3525.4 4076.2 4191 4427.9 4072.6 3726.7 3871.3 3019.8 2995.3 TRUE FALSE FALSE 3233.56107 3830.119867 4227.267558 4173.658752 4375.100184 3227.896852 3831.261172 5051.641549 2688.535495 3099.386452 1.043290703 1.235767119 1.363904638 1.346608052 1.411602023 1.041463174 1.236135355 1.629884374 0.867441197 1 11.59776694 -7.180369216 2.631534151 1.017670259 1.3236962 0.550951373 0.146462665 0.168591132 2.250101371 0.023790027 0.029061484 6.60E-08 7.180369216 0.306025941 GEAGT(ph)PVAAGTTAAAIPR ddPTM_HeLa_Curcumin_4h_R1 1 GEAGTPVAAGTTAAAIPR 18 0 A0A0C4DGH3;Q9Y6R0;M0QXQ4 A0A0C4DGH3 NUMBL Numb-like protein 1 0 GEAGT(1)PVAAGTTAAAIPR 140.75 0.00084732 4883400 941.22 1052.9 934.95 1005.9 1249.7 1318.5 1153.4 635.58 838.67 768.6 TRUE FALSE FALSE 866.7214438 1143.907984 969.6000695 1001.737852 1234.798144 1045.028237 1185.7613 829.3654161 746.6699992 795.3087928 1.089792357 1.438319298 1.219149189 1.259558377 1.552602153 1.313990549 1.490944537 1.042821887 0.938842882 1 9.635371311 -7.387190234 4.694902271 1.038650456 1.337535916 0.519322047 0.141367386 0.130885194 4.395766532 0.02256691 0.025614577 4.10E-08 7.387190234 0.29888546 GEAGVPAEFSIWTR ddPTM_HeLa_Curcumin_4h_R1 2 GEAGVPAEFSIWTR 14 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3 O75369-8 FLNB Filamin-B 0 0 ; ; 213.63 8.38E-13 59835000 2578.18 2126.22 2085.33 1931.93 2192.43 2985.7 2160.35 2152.35 2835.82 2380.66 FALSE FALSE TRUE 2374.114333 2310.000983 2162.614164 1923.936186 2166.286704 2366.432164 2220.963607 2808.591607 2524.737641 2463.387758 0.963759897 0.937733402 0.877902457 0.781012319 0.879393306 0.960641359 0.901589122 1.140133784 1.02490468 1 11.26642802 -7.436973818 1.815044832 0.986603309 0.916148151 0.119776211 0.086848352 0.552843845 3.535559832 0.016599186 0.018422339 3.66E-08 7.436973818 -0.070455157 GEAHLAVNDFELAR ddPTM_HeLa_Curcumin_4h_R1 1 GEAHLAVNDFELAR 14 0 Q02790 Q02790 FKBP4 "Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed" 0 0 86.738 0.010338 5396900 3598.6 3373.5 3704.8 3426.5 3712.9 4497.5 3184.1 3099.4 3544.7 3224.9 FALSE FALSE TRUE 3313.767013 3665.090308 3842.103147 3412.322051 3668.626092 3564.667803 3273.437276 4044.392792 3155.855278 3336.965035 0.993048167 1.09833045 1.151376507 1.022582501 1.099390031 1.068236486 0.980962414 1.211997354 0.945726205 1 11.70432085 -7.26519248 24.16705523 0.996717187 1.085429815 0.391094517 0.062058662 164.4202733 1058737.756 0.009311229 0.010867214 5.43E-08 7.26519248 0.088712628 GEATVSFDDPPSAK ddPTM_HeLa_Curcumin_4h_R1 2 GEATVSFDDPPSAK 14 0 Q92804-2;Q92804;A0A075B7D9;H3BPE7;P35637-2;P35637 Q92804-2;H3BPE7 TAF15;FUS TATA-binding protein-associated factor 2N;RNA-binding protein FUS 0 0 ; ; 231.17 4.96E-37 5805700 6102.6 5360.6 5271.1 5633 5506.5 6294.9 4873.8 5486.9 5938.2 5438.3 FALSE FALSE TRUE 5619.572771 5823.946378 5466.451603 5609.692139 5440.838584 4989.266782 5010.545711 7159.830551 5286.794317 5627.28052 0.998630289 1.03494865 0.97141978 0.996874444 0.966868199 0.886621302 0.89040269 1.272342924 0.93949365 1 12.45822217 GEAVLRPGLDAEPELS(ph)PEEQR ddPTM_HeLa_Curcumin_4h_R1 1 GEAVLRPGLDAEPELSPEEQR 21 1 C9JQV0;Q9BRJ6 C9JQV0 C7orf50 Uncharacterized protein C7orf50 1 0 GEAVLRPGLDAEPELS(1)PEEQR 87.419 0.00029645 62609000 1256.7 1112.6 1008.8 1317.9 1633.1 1733.7 1214.2 887.04 1276.4 1102 TRUE FALSE FALSE 1157.230869 1208.768186 1046.187015 1312.446879 1613.626349 1374.111077 1248.267184 1157.494413 1136.382113 1140.294418 1.0148527 1.060049201 0.917470961 1.150971941 1.415096245 1.205049376 1.094688498 1.015083819 0.99656904 1 10.15519065 -6.109793096 6.486006065 1.006292618 1.190160335 0.438913268 0.100865692 0.178235935 9.223916564 0.015450678 0.025793066 7.77E-07 6.109793096 0.183867716 GECSGPATVNNSSDT(ph)ESIPSPHTEAAK ddPTM_HeLa_Curcumin_4h_R1 1 GECSGPATVNNSSDTESIPSPHTEAAK 27 0 Q9Y618;A0A384DVL6;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 GECSGPAT(0.001)VNNS(0.032)S(0.143)DT(0.676)ES(0.143)IPS(0.004)PHTEAAK 84.674 3.42E-05 7244900 1094.1 884.83 899.97 847.28 1267.3 1331.9 934.5 380.1 888.99 1014.6 TRUE FALSE FALSE 1007.500831 961.3107625 933.3236799 843.7741799 1252.188275 1055.648926 960.7195549 495.9907402 791.4700211 1049.857274 0.959655046 0.915658524 0.889000536 0.803703704 1.192722388 1.005516609 0.915095393 0.472436351 0.753883447 1 10.0359775 -4.264095477 3.680596308 0.972937994 0.419290331 0.575621861 0.117179059 0.107054887 2.675499964 0.012873282 0.160959726 5.44E-05 4.264095477 -0.553647663 GEDLTEEEDGGIIRR ddPTM_HeLa_Curcumin_4h_R1 2 GEDLTEEEDGGIIRR 15 1 Q02790 Q02790 FKBP4 "Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed" 0 0 ; ; 119.39 0.0020068 9675500 3081.3 2380.1 3292.4 3060 3692.3 3566 2704.3 2658.4 3032 2778.3 FALSE FALSE TRUE 2837.411854 2585.825238 3414.41924 3047.338531 3648.271734 2826.371403 2780.17538 3468.933922 2699.397186 2874.845718 0.986978827 0.899465742 1.187687819 1.06000072 1.269032182 0.983138464 0.967069419 1.206650465 0.938971148 1 11.48926882 -6.760263192 24.99974972 0.986600405 1.104544448 0.37624041 0.094899075 30.89618095 656684.4961 0.014321935 0.019614952 1.74E-07 6.760263192 0.117944043 GEDVPS(ph)EEEEEEENGFEDR ddPTM_HeLa_Curcumin_4h_R1 2 GEDVPSEEEEEEENGFEDR 19 0 Q9ULX3 Q9ULX3 NOB1 RNA-binding protein NOB1 1 0 GEDVPS(1)EEEEEEENGFEDR;GEDVPS(1)EEEEEEENGFEDR ; 214.63 3.04E-18 33802000 10923.5 10423.8 11728.1 9217.5 14515.3 12537.9 10354.6 9718.2 9410.9 9383 TRUE FALSE FALSE 10058.89345 11324.78682 12162.7537 9179.360427 14342.21453 9937.398209 10645.12221 12681.23444 8378.547815 9709.058552 1.036031804 1.166414515 1.252722253 0.945442895 1.477199303 1.023518208 1.096411372 1.306124005 0.862961921 1 13.24511569 -7.287822175 3.728047082 1.015546005 1.177812865 0.290723887 0.148221629 0.242844214 7.229220957 0.022263306 0.026011503 5.15E-08 7.287822175 0.16226686 GEEGS(ph)DDDETENGPKPK ddPTM_HeLa_Curcumin_4h_R1 4 GEEGSDDDETENGPKPK 17 1 Q6PD62 Q6PD62 CTR9 RNA polymerase-associated protein CTR9 homolog 1 0 GEEGS(1)DDDETENGPKPK;GEEGS(1)DDDETENGPKPK;GEEGS(1)DDDETENGPKPK;GEEGS(0.987)DDDET(0.013)ENGPKPK ;;; 268.13 2.76E-51 215634600 11968.1 10695.2 11401.4 11287.4 12650.5 12815.2 10298.5 8579.4 10721.9 10138.5 TRUE FALSE FALSE 11020.81226 11619.64543 11823.94591 11240.69573 12499.65105 10157.18306 10587.44819 11195.21957 9545.734395 10490.81212 1.050520411 1.10760209 1.12707632 1.071480034 1.19148555 0.968197976 1.009211496 1.067145178 0.909913769 1 13.35683874 -8.223437478 1.083301332 1.009296716 1.075220633 0.27802133 0.066096784 0.556876414 1.356901374 0.017349355 0.012416026 5.98E-09 8.223437478 0.065923917 GEELSCEER ddPTM_HeLa_Curcumin_4h_R1 1 GEELSCEER 9 0 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 0 112.84 0.0026941 1344100 514.55 586.1 582.13 467.77 500.62 475.15 491.2 418.19 321.98 354.18 FALSE FALSE TRUE 473.8228245 636.7598724 603.7042499 465.8344917 494.6504335 376.598534 504.98175 545.6942059 286.6595996 366.4877286 1.292875007 1.737465739 1.647270025 1.271078007 1.34970531 1.027588387 1.377895385 1.488983568 0.782180622 1 8.517621082 -8.428757845 1.059787847 1.04341213 1.394280414 0.458883623 0.206677283 0.37607017 0.86511926 0.06661527 0.041598522 3.73E-09 8.428757845 0.350868283 GEES(ph)S(ph)EEEEKGYK ddPTM_HeLa_Curcumin_4h_R1 1 GEESSEEEEKGYK 13 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 2 0 GEES(0.999)S(0.997)EEEEKGY(0.003)K 105.65 0.019885 8780300 5991 4648.6 5425.1 5283.6 6676 5815.4 5156.2 4284 4825.6 4492.9 TRUE FALSE FALSE 5516.806028 5050.40427 5626.158978 5261.737863 6596.39306 4609.220487 5300.869095 5590.171879 4296.243753 4649.027941 1.186657964 1.086335538 1.210179644 1.131793125 1.418875762 0.991437467 1.140210204 1.202438865 0.92411657 1 12.18271338 -9.359946186 0.632934661 0.971786629 1.173837 0.372487042 0.105933295 1.167613976 0.652382383 0.137049629 0.021518254 4.37E-10 9.359946186 0.202050371 GEFSAS(ph)PMLK ddPTM_HeLa_Curcumin_4h_R1 2 GEFSASPMLK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 GEFS(0.005)AS(0.995)PMLK;GEFS(0.01)AS(0.99)PMLK ; 152.7 0.00065662 73292000 3940.7 3574.4 3620.4 3809.2 3409.8 3536 3600.1 2562.5 4074.1 3705 TRUE FALSE FALSE 3628.789437 3883.355209 3754.575209 3793.43854 3369.140362 2802.593741 3701.109117 3343.794454 3627.181423 3833.748474 0.946538215 1.012939486 0.979348341 0.989485504 0.878811008 0.731032242 0.965402175 0.872199748 0.946118778 1 11.90453997 -5.706701629 5.457863297 0.97867792 0.858042597 0.509981662 0.056454605 0.121045322 7.538425995 0.007955377 0.015949988 1.96E-06 5.706701629 -0.120635323 GEGDAPFSEPGT(ph)TSTQRPSSPETATK ddPTM_HeLa_Curcumin_4h_R1 1 GEGDAPFSEPGTTSTQRPSSPETATK 26 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 GEGDAPFS(0.08)EPGT(0.302)T(0.256)S(0.256)T(0.066)QRPS(0.018)S(0.018)PET(0.003)ATK 62.442 0.0023368 190630000 2412.2 2431.5 2663.6 2379.4 3009.2 3344.8 2257.6 2121.8 2539.1 1959.6 TRUE FALSE FALSE 2221.271825 2641.668025 2762.315359 2369.554673 2973.317255 2651.050776 2320.94218 2768.727052 2260.567083 2027.695954 1.095465925 1.302792966 1.362292682 1.168594665 1.46635261 1.307420262 1.144620413 1.36545474 1.114845191 1 10.98562563 -7.381041778 2.523030331 1.037746851 1.301558549 0.565704596 0.092788983 0.128074792 1.536751289 0.016117556 0.018295075 4.16E-08 7.381041778 0.263811698 GEGDAPFSEPGTTSTQRPS(ph)SPETATK ddPTM_HeLa_Curcumin_4h_R1 3 GEGDAPFSEPGTTSTQRPSSPETATK 26 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 GEGDAPFSEPGT(0.005)T(0.092)S(0.068)T(0.068)QRPS(0.378)S(0.378)PET(0.01)AT(0.001)K;GEGDAPFS(0.001)EPGT(0.005)T(0.004)S(0.004)T(0.004)QRPS(0.456)S(0.456)PET(0.067)AT(0.003)K;GEGDAPFSEPGT(0.026)T(0.032)S(0.032)T(0.129)QRPS(0.427)S(0.337)PET(0.014)AT(0.004)K ;; 82.885 3.58E-05 1096870000 8654.8 6959.9 7194.1 8019.3 8573.7 8995.7 7443.8 6156.1 6997.4 6161.8 TRUE FALSE FALSE 7969.763447 7561.482743 7460.719675 7986.118261 8471.464227 7129.890418 7652.652994 8033.066551 6229.802727 6375.922091 1.249978173 1.185943403 1.170139717 1.252543263 1.328664953 1.118252437 1.200242551 1.259906636 0.97708263 1 12.63841829 -9.322023677 0.763378585 0.980282581 1.221802288 0.733896961 0.055618443 0.368134346 0.333621536 0.056905618 0.011068896 4.76E-10 9.322023677 0.241519706 STT(ph)SVSEEDVSSR ddPTM_HeLa_Curcumin_4h_R1 2 STTSVSEEDVSSR 13 0 Q96IZ0 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 1 0 STT(0.483)S(0.483)VS(0.034)EEDVSSR;STT(0.76)S(0.222)VS(0.018)EEDVSSR ; 240.18 2.24E-26 193320000 4708.5 3794.1 4149.1 4597.5 4871.5 5092 4478.5 13507.1 4577.4 3755.7 TRUE FALSE FALSE 4335.817257 4122.045098 4302.869296 4578.476763 4813.410544 4035.861801 4604.154657 17625.35261 4075.270672 3886.210295 1.115692906 1.060685034 1.107214733 1.178134073 1.238587256 1.03850834 1.184741511 4.535357397 1.048649034 1 11.92414826 -4.2613361 5.803216469 1.081840313 4.64050133 0.995690476 0.0676582 0.006898244 1.018165125 0.01103324 0.096562365 5.48E-05 4.2613361 3.558661017 up GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPS(ph)PVAPAPVPSRR ddPTM_HeLa_Curcumin_4h_R1 1 GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPSPVAPAPVPSRR 43 2 Q9UK76;Q9UK76-3 Q9UK76;Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 1 0 GEGDIHENVDTDLPGS(0.001)LGQS(0.001)EEKPVPAAPVPS(0.962)PVAPAPVPS(0.035)RR 55.598 2.49E-05 9979000 1136 1125.3 922.67 1028.5 1035.4 1369.1 1143.8 1596.2 978.4 1119 TRUE FALSE FALSE 1046.084401 1222.565918 956.8649619 1024.24434 1023.053531 1085.133227 1175.89195 2082.874032 871.0719678 1157.885167 0.903443995 1.05586111 0.826390206 0.884581968 0.883553534 0.93716826 1.015551441 1.798860623 0.752295645 1 10.17727647 -4.258428272 3.891404075 0.941265695 1.883788682 0.90485723 0.085750681 0.04215902 1.265282278 0.009162127 0.112999543 5.52E-05 4.258428272 0.942522987 GQLTNIVSPT(ph)AATTPR ddPTM_HeLa_Curcumin_4h_R1 1 GQLTNIVSPTAATTPR 16 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 GQLT(0.175)NIVS(0.235)PT(0.586)AAT(0.004)TPR 171.15 0.00031783 16918000 2370.4 2110.7 1904.2 2073 1991.7 2691.8 2159.9 3715.9 2274.9 2099.7 TRUE FALSE FALSE 2182.780339 2293.139503 1974.771327 2064.422475 1967.950278 2133.490337 2220.500981 4848.860804 2025.349162 2172.664419 1.004655997 1.055450388 0.908916863 0.950180091 0.905777377 0.981969566 1.022017465 2.231757819 0.932196037 1 11.08524964 -4.261304106 5.935177809 0.988109119 2.266749719 0.984376463 0.047543767 0.010888526 1.782383339 0.006453194 0.055913222 5.48E-05 4.261304106 1.2786406 up GEGEPCGGGGAGR ddPTM_HeLa_Curcumin_4h_R1 1 GEGEPCGGGGAGR 13 0 Q16270-2;Q16270 Q16270-2 IGFBP7 Insulin-like growth factor-binding protein 7 0 0 105.98 0.0032054 217500 159.29 0 0 0 78.517 0 0 0 159.03 71.415 FALSE FALSE TRUE 146.6820284 0 0 0 77.58073606 0 0 0 141.5848069 73.89666593 1.984961386 0 0 0 1.049854348 0 0 0 1.915983693 1 6.207437369 -7.251614367 24.94161999 1.465120656 0.161516013 0.735012361 0.404415513 311.1137996 789788.992 0.078515617 0.095530405 5.60E-08 7.251614367 -1.303604643 GEGERPAQNEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GEGERPAQNEKR 12 2 A0A087X0X3;P52272-2;P52272;M0R2T0;M0QYQ7;M0R0N3;M0R019;M0R0Y6 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 1 ; GEGERPAQNEK(1)R;GEGERPAQNEK(1)R 110.64 0.00071313 6522000 2196.71 2110.04 2016.86 1870.18 1954.42 2981.4 1503.21 803.68 2036.4 1901.56 FALSE TRUE FALSE 2022.838086 2292.422455 2091.606606 1862.441691 1931.114818 2363.024033 1545.386027 1048.718332 1813.012015 1967.639068 1.028053426 1.165062481 1.06300319 0.946536243 0.981437525 1.200943847 0.78540117 0.532983081 0.92141493 1 10.94224989 -4.516784843 4.174779439 1.030853941 0.569992359 0.776814707 0.086059384 0.060642663 2.435797312 0.010819894 0.0569194 3.04E-05 4.516784843 -0.460861582 GEGPDVDVNLPK ddPTM_HeLa_Curcumin_4h_R1 2 GEGPDVDVNLPK 12 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 166.86 1.71E-06 11607800 6810.5 5621.7 6273.3 6215 8115.8 7804.9 6583.2 6359.7 6716.9 5371.3 FALSE FALSE TRUE 6271.441739 6107.614698 6505.794017 6189.283977 8019.024386 6186.075761 6767.906874 8298.743254 5980.072875 5557.952275 1.128372722 1.098896571 1.170537942 1.113590702 1.442801951 1.113013472 1.217697911 1.493129635 1.075948943 1 12.44033773 -1 0.145619551 0.959995075 2.451971836 0.526339257 0.104307486 38.24438607 0.363575708 0.234842445 12.02476926 0.1 1 1.491976761 SQSS(ph)DT(ph)EQQSPTSGGGK ddPTM_HeLa_Curcumin_4h_R1 2 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 0 SQS(0.206)S(0.795)DT(0.712)EQQS(0.287)PTSGGGK;S(0.004)QS(0.163)S(0.861)DT(0.97)EQQS(0.001)PTSGGGK ; 187.75 4.21E-06 45200000 5115.89 4737.64 4370.29 5369.45 5841.6 9633.2 11666.3 14443.5 6169.4 5280.41 TRUE FALSE FALSE 4710.961908 5147.140491 4532.256792 5347.232639 5771.942735 7635.165731 11993.62498 18847.25666 5492.632255 5463.903854 0.862197073 0.942026183 0.829490583 0.978646913 1.056377068 1.397382885 2.195065158 3.449412208 1.005257853 1 12.41571638 -4.261291062 1.110952213 0.924900669 4.734743253 0.995321432 0.054118417 0.084887854 0.082905972 0.009459702 0.377961226 5.48E-05 4.261291062 3.809842584 up GEGQLGPAER ddPTM_HeLa_Curcumin_4h_R1 1 GEGQLGPAER 10 0 P13639 P13639 EEF2 Elongation factor 2 0 0 119.22 0.0030599 7496100 1187.5 977.62 1188.2 1275.1 1143.9 994.98 895.13 1043.8 1102.5 1033.4 FALSE FALSE TRUE 1093.508122 1062.121117 1232.235737 1269.823974 1130.25974 788.6099323 920.2449387 1362.049815 981.5585083 1069.310573 1.022629112 0.99327655 1.152364681 1.187516523 1.056998563 0.737493813 0.860596502 1.27376447 0.917935849 1 10.06246522 -4.238349198 23.61699916 1.008328572 1.273765099 0.302638808 0.126123358 3062.374859 3132142.157 0.017583714 1.180741834 5.78E-05 4.238349198 0.265436528 GEIIGVK ddPTM_HeLa_Curcumin_4h_R1 2 GEIIGVK 7 0 Q15181;Q5SQT6 Q15181 PPA1 Inorganic pyrophosphatase 0 0 ; ; 119.57 0.0095785 16413700 7384.1 5116.2 6898.5 6712.9 6422.8 7983.9 6532 6219.3 7214.9 6444.7 FALSE FALSE TRUE 6799.640693 5558.421531 7154.164479 6685.123798 6346.212305 6327.949143 6715.27034 8115.53594 6423.443521 6668.652845 1.019642325 0.833514903 1.072805054 1.002469907 0.951648324 0.948909666 1.006990542 1.216967824 0.963229556 1 12.70317963 -4.264430963 5.037807693 0.993128428 1.227311864 0.570962858 0.061027635 0.090524962 7.24099075 0.007990783 0.073360377 5.44E-05 4.264430963 0.234183436 GEIKDSS(ph)PSS(ph)SPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 GEIKDSSPSSSPSPK 15 1 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 3 0 GEIKDS(0.372)S(0.602)PS(0.116)S(0.887)S(0.033)PS(0.99)PK 120.59 0.0062488 11293000 3101.3 2457.4 3488 3280.7 3234.5 3555 2628.2 2338.8 3883.2 3184.6 TRUE FALSE FALSE 2855.828833 2669.806706 3617.268348 3267.125333 3195.9307 2817.652927 2701.940219 3051.889353 3457.222675 3295.264613 0.866646284 0.810194937 1.09771711 0.991460692 0.969855558 0.855061204 0.819946358 0.92614394 1.049148727 1 11.6861786 -5.253261473 23.97853042 0.944359437 0.862340076 0.199341902 0.083919256 517.2748722 1516697.51 0.012176139 0.030428717 5.58E-06 5.253261473 -0.082019361 GEIKDSSPS(ph)SSPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 GEIKDSSPSSSPSPK 15 1 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 2 0 GEIKDS(0.052)S(0.073)PS(0.771)S(0.103)S(0.002)PS(0.998)PK 165.45 0.00094991 12314000 10008 7932.8 9622.5 10485 9241.5 10185 6331.2 4098.1 11462 8161.8 TRUE FALSE FALSE 9215.85624 8618.475884 9979.118315 10441.61585 9131.301148 8072.516191 6508.836432 5347.591825 10204.64728 8445.421942 1.091225081 1.020490858 1.181600917 1.236364023 1.081213137 0.95584522 0.770694049 0.633194157 1.208305203 1 13.04395379 -4.729461005 1.975343946 1.069581726 0.637790769 0.792736241 0.083133821 0.135100537 0.947303588 0.012068488 0.075380184 1.86E-05 4.729461005 -0.431790957 GEK(ac)GDPGLIGPK ddPTM_HeLa_Curcumin_4h_R1 1 GEKGDPGLIGPK 12 1 Q15848 Q15848 ADIPOQ Adiponectin 0 1 GEK(1)GDPGLIGPK 95.523 0.013984 1162400000 2178.7 1583.9 1951.4 3374.2 1597.9 3756.8 2514.8 1261.2 3064.2 1296.7 FALSE TRUE FALSE 2006.253596 1720.805258 2023.720601 3360.238454 1578.846086 2977.597332 2585.35852 1645.734074 2728.064926 1341.760228 1.495240024 1.282498334 1.508258001 2.504350914 1.176697634 2.219172449 1.926840925 1.226548559 2.033198532 1 10.38991117 -8.034556092 0.432533402 0.983879132 1.80946185 0 0.508619315 0.86976407 0.400458988 0.293707465 0.166121865 9.24E-09 8.034556092 0.825582718 GELIPIS(ph)PSTEVGGSGIGTPPSVLKR ddPTM_HeLa_Curcumin_4h_R1 1 GELIPISPSTEVGGSGIGTPPSVLKR 26 1 P10244-2;P10244 P10244-2 MYBL2 Myb-related protein B 1 0 GELIPIS(0.453)PS(0.453)T(0.094)EVGGSGIGTPPSVLKR 105.57 1.06E-07 17529000 2665.8 1889.8 2243.5 2317.7 1921.5 2709.6 2393.6 1626.8 3086 1950.8 TRUE FALSE FALSE 2454.799117 2053.145891 2326.646084 2308.109972 1898.587367 2147.598417 2460.757974 2122.803831 2747.473521 2018.590155 1.216095853 1.017118748 1.152609448 1.143426746 0.940551188 1.063910082 1.219047843 1.051626962 1.361085367 1 10.97913231 GELIPISPST(ph)EVGGSGIGTPPSVLKR ddPTM_HeLa_Curcumin_4h_R1 1 GELIPISPSTEVGGSGIGTPPSVLKR 26 1 P10244-2;P10244 P10244-2 MYBL2 Myb-related protein B 1 0 GELIPIS(0.058)PS(0.243)T(0.699)EVGGSGIGTPPSVLKR 85.913 2.87E-05 18461000 1858.6 1179.1 1245.5 1317.2 1252 2187.7 1885 2712.6 1829.4 1758 TRUE FALSE FALSE 1711.489849 1281.01615 1291.659326 1311.749775 1237.070718 1733.94636 1937.888027 3539.659253 1628.719397 1819.090369 0.940849272 0.704206988 0.710057811 0.72110204 0.680049072 0.953194184 1.065306078 1.945840247 0.89534826 1 10.8290015 -4.223762733 2.481319591 0.894138064 2.241385047 0.87016466 0.127521235 0.201358281 1.4016197 0.022387028 0.594157562 5.97E-05 4.223762733 1.347246982 GELS(ph)PSFLNPPLPPSIDDR ddPTM_HeLa_Curcumin_4h_R1 1 GELSPSFLNPPLPPSIDDR 19 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 GELS(0.743)PS(0.257)FLNPPLPPSIDDR 174.19 2.14E-06 2522500 740.88 590.6 638.89 744.52 601.03 411.1 407.22 530.96 729.32 532.85 TRUE FALSE FALSE 682.2385662 641.6488323 662.5678254 741.4393735 593.8631098 325.8332259 418.6454972 692.8472598 649.3154207 551.3664978 1.237359486 1.163742873 1.201683142 1.344730549 1.077075071 0.590955793 0.759287151 1.256600215 1.177647578 1 9.106867799 -5.501312758 24.30446485 1.143803444 0.85398723 0.377337135 0.177467684 474.2070499 534421.6491 0.026443772 0.058570664 3.15E-06 5.501312758 -0.289816213 GELS(ph)PSFLNPPLPPSIDDRDLSTEEVR ddPTM_HeLa_Curcumin_4h_R1 1 GELSPSFLNPPLPPSIDDRDLSTEEVR 27 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 GELS(0.533)PS(0.057)FLNPPLPPS(0.409)IDDRDLSTEEVR 67.033 0.00024534 7196500 857.98 652.53 559.84 591.54 689.08 782.03 517.72 916.39 781.97 667.59 TRUE FALSE FALSE 790.0699777 708.9317856 580.5881629 589.0923642 680.8631711 619.8281627 532.2458298 1195.793092 696.1898474 690.7887028 1.143721625 1.026264302 0.840471421 0.852782279 0.985631595 0.897276056 0.770490061 1.731054789 1.007818809 1 9.432100679 -4.249775257 24.96586714 1.005136035 1.731055229 0.792256148 0.117083317 746.9938189 1598835.28 0.019345807 0.419640325 5.63E-05 4.249775257 0.725919194 GELSPS(ph)FLNPPLPPSIDDRDLSTEEVR ddPTM_HeLa_Curcumin_4h_R1 1 GELSPSFLNPPLPPSIDDRDLSTEEVR 27 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 GELS(0.096)PS(0.564)FLNPPLPPS(0.339)IDDRDLS(0.002)TEEVR 58.802 0.0017523 13215000 1330.9 1217 1308.4 1292.4 1333.1 1375.4 867.74 937.06 1256.2 1312.5 TRUE FALSE FALSE 1225.557861 1322.192057 1356.890455 1287.052391 1317.203653 1090.126536 892.086449 1222.76528 1118.398003 1358.109277 0.902400036 0.973553512 0.999102559 0.947679552 0.969880462 0.802679544 0.656859108 0.900343809 0.823496328 1 10.40738385 -5.203424902 4.713261353 0.958451283 0.769012004 0.480735302 0.074462062 0.099203624 4.632577979 0.008646989 0.022616889 6.26E-06 5.203424902 -0.189439278 LQS(ph)EPESIR ddPTM_HeLa_Curcumin_4h_R1 2 LQSEPESIR 9 0 P09496-2;P09496-4;P09496-3;P09496;F8WF69 P09496-2 CLTA Clathrin light chain A 1 0 LQS(1)EPESIR;LQS(0.981)EPES(0.019)IR ; 117.09 0.0069885 12188400 2006.56 1977.99 1666.83 2238 2128.64 2479.1 2186.25 9000.5 1804.47 1985.66 TRUE FALSE FALSE 1847.738659 2148.958642 1728.604186 2228.739749 2103.257358 1964.906715 2247.590291 11744.71102 1606.524156 2054.661537 0.899291015 1.045894228 0.841308486 1.084723546 1.023651497 0.956316493 1.09389807 5.716129301 0.781892359 1 11.00468504 -4.261287351 5.958119462 0.966728596 5.847965891 0.99611664 0.088943125 0.004184899 0.697403195 0.009516133 0.082328525 5.48E-05 4.261287351 4.881237295 up GEPNVS(ph)YICSR ddPTM_HeLa_Curcumin_4h_R1 1 GEPNVSYICSR 11 0 P49841;P49841-2;A0A3B3ITW1;A8MT37;P49840 P49841 GSK3B;GSK3A Glycogen synthase kinase-3 beta;Glycogen synthase kinase-3 alpha 1 0 GEPNVS(0.653)Y(0.347)ICSR 147.3 0.00083625 910750000 2415 1960.9 2380.3 2333.8 2096.2 2310.5 1866.6 1563.7 2827.8 2121.9 TRUE FALSE FALSE 2223.850202 2130.391458 2468.516012 2324.143354 2071.204184 1831.276255 1918.971772 2040.464932 2517.597415 2195.635867 1.012850188 0.970284504 1.124282969 1.058528597 0.943327723 0.834052806 0.873993635 0.929327564 1.146637041 1 11.1004231 -5.535149427 5.179672217 1.016130009 0.8794092 0.591486206 0.061273874 0.082607767 6.545539765 0.006777712 0.014293313 2.92E-06 5.535149427 -0.136720809 GEPNVSY(ph)ICSR ddPTM_HeLa_Curcumin_4h_R1 1 GEPNVSYICSR 11 0 P49841;P49841-2;A0A3B3ITW1;A8MT37;P49840 P49841 GSK3B;GSK3A Glycogen synthase kinase-3 beta;Glycogen synthase kinase-3 alpha 1 0 GEPNVS(0.007)Y(0.993)ICSR 160.91 0.0020718 949170000 4886.6 4668.4 4777.4 4614.2 4476.1 5654.3 4322.6 3240 5034.6 4480.1 TRUE FALSE FALSE 4499.820454 5071.915694 4954.454647 4595.107663 4422.725431 4481.534443 4443.880522 4227.861085 4482.316976 4635.783142 0.970671042 1.094079585 1.068741677 0.991225759 0.954040622 0.966726507 0.958604056 0.912005794 0.96689531 1 12.17859736 -5.788100801 4.270394692 1.0023096 0.949359669 0.371735406 0.041122488 0.241789697 9.916646431 0.006784415 0.013095458 1.63E-06 5.788100801 -0.052949931 GEQVSQNGLPAEQGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 GEQVSQNGLPAEQGSPR 17 0 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR;GEQVSQNGLPAEQGS(1)PR ;;; 299.93 5.30E-95 239245000 13100.2 12507.9 14700.2 14883.3 15265.8 14326.4 12048.2 10902 14335.6 14288.3 TRUE FALSE FALSE 12063.30535 13589.02714 15245.00234 14821.71685 15083.76531 11354.94315 12386.24007 14225.96961 12763.02055 14784.81736 0.815925219 0.919120393 1.03112551 1.002495769 1.020219928 0.768013758 0.83776754 0.962201241 0.863251823 1 13.8518288 -5.26133072 24.99995645 0.933813084 0.854171523 0.20632614 0.080304959 16.21947307 3731079.559 0.013750359 0.032734177 5.48E-06 5.26133072 -0.079641561 GERINSS(ph)WEK ddPTM_HeLa_Curcumin_4h_R1 1 GERINSSWEK 10 1 A0A096LP21;A0A087WTW5;Q9UKL3 A0A096LP21 CASP8AP2 CASP8-associated protein 2 1 0 GERINS(0.001)S(0.999)WEK 68.557 0.020113 8913200 169.9 0 243.34 250.63 108.8 156.95 150.24 94.925 232.33 212.06 TRUE FALSE FALSE 156.4522357 0 252.3583945 249.5929595 107.5026311 124.3968008 154.45533 123.8671955 206.8439803 219.4290692 0.712996853 0 1.150068199 1.137465334 0.489919733 0.566911218 0.703896392 0.564497657 0.942646209 1 7.777610852 -8.783553417 0.990003184 0.977453894 0.675283587 0.130926282 0.310031798 0.773777587 1.506734667 0.133706221 0.061219234 1.65E-09 8.783553417 -0.302170307 GES(ph)ENAGTNQETR ddPTM_HeLa_Curcumin_4h_R1 2 GESENAGTNQETR 13 0 Q08170 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 1 0 GES(1)ENAGTNQETR;GES(0.997)ENAGT(0.001)NQET(0.002)R ; 176.43 0.00020719 42943000 2322 2094.21 2624.7 2300.4 2741.4 2418.8 1918.71 1520.91 2076.31 1652.42 TRUE FALSE FALSE 2138.21125 2275.224181 2721.973691 2290.881554 2708.710595 1917.113615 1972.543839 1984.628458 1848.543988 1709.841472 1.250531868 1.330663818 1.591945064 1.339821025 1.584188148 1.121223017 1.153641359 1.160709042 1.081120103 1 10.73964686 -8.510994401 0.846447824 1.023471022 1.325236259 0.330678987 0.156675647 0.453401962 0.669253222 0.068759197 0.03556639 3.08E-09 8.510994401 0.301765238 GES(ph)LDNLDSPR ddPTM_HeLa_Curcumin_4h_R1 1 GESLDNLDSPR 11 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 GES(1)LDNLDSPR 164.93 0.00027186 7817500 1889.7 2169.9 1785.1 1768.8 1936.7 1968 2059.5 2478.9 2392.9 1947.3 TRUE FALSE FALSE 1740.128251 2357.456487 1851.257376 1761.481174 1913.606117 1559.814616 2117.284027 3234.705199 2130.404857 2014.96853 0.863600709 1.169971864 0.918752501 0.874197859 0.949695287 0.774113636 1.050777715 1.605337826 1.057289394 1 10.97654159 -4.283775303 3.615921386 0.937128344 1.665902079 0.774270728 0.105042926 0.080028113 1.892257486 0.013670326 0.151531067 5.20E-05 4.283775303 0.728773735 GESAADS(ph)DGWDSAPSDLR ddPTM_HeLa_Curcumin_4h_R1 2 GESAADSDGWDSAPSDLR 18 0 I3L4Q4;Q9BUL5-4;Q9BUL5;A0A087WVQ2;I3L0Y2;Q9BUL5-2 I3L4Q4 PHF23 PHD finger protein 23 1 0 GES(0.035)AADS(0.87)DGWDS(0.094)APSDLR;GES(0.001)AADS(0.988)DGWDS(0.011)APSDLR ; 227 1.71E-23 10260200 2420.07 2476.2 2627.2 2449.8 2959.71 4581.4 3439 2642.6 2538.9 2575.56 TRUE FALSE FALSE 2228.518906 2690.231694 2724.566343 2439.663377 2924.417391 3631.165997 3535.489084 3448.316575 2260.389022 2665.060518 0.836198237 1.00944488 1.022328133 0.915425132 1.097317442 1.362507895 1.32660743 1.293898038 0.848156733 1 11.37995258 -5.472308545 2.881655403 0.935986075 1.328146055 0.884618144 0.062714845 0.072749219 1.191838303 0.010973816 0.026119076 3.37E-06 5.472308545 0.39215998 GESDEPAPQVQPES(ph)PETVSPK ddPTM_HeLa_Curcumin_4h_R1 1 GESDEPAPQVQPESPETVSPK 21 0 A0A1B0GTL5 A0A1B0GTL5 1 0 GESDEPAPQVQPES(0.99)PET(0.009)VS(0.001)PK 113.52 9.84E-06 6173200 5068.8 4495.4 4818.3 5057.5 4971.8 5463.2 4194.2 4849.4 4703.2 4678.1 TRUE FALSE FALSE 4667.599131 4883.962345 4996.870437 5036.573405 4912.514532 4330.070737 4311.877964 6327.959736 4187.270727 4840.663627 0.964247775 1.00894479 1.03226971 1.040471678 1.014843193 0.894520064 0.890761742 1.307250457 0.865019974 1 12.24098913 -7.07687415 6.589793445 0.983186765 1.017586834 0.067310496 0.114231601 0.949406396 67.91088599 0.016989378 0.020905061 8.38E-08 7.07687415 0.034400069 GESEDDFWWCIDR ddPTM_HeLa_Curcumin_4h_R1 1 GESEDDFWWCIDR 13 0 Q96HN2-2;Q96HN2;H0Y8B3;O43865-2;Q96HN2-4;Q96HN2-3;O43865 Q96HN2-2 AHCYL2;AHCYL1 Putative adenosylhomocysteinase 3;Adenosylhomocysteinase;Putative adenosylhomocysteinase 2 0 0 210.91 1.29E-08 18005000 2015.5 1851 2144.9 2324.5 1768.1 2488.1 1986.1 1904.6 1960.8 1986.7 FALSE FALSE TRUE 1855.971048 2010.992192 2224.391881 2314.881835 1747.016562 1972.040013 2041.824621 2485.303772 1745.705146 2055.737677 0.902824844 0.978233855 1.082040722 1.126058962 0.849824655 0.959285825 0.993232086 1.208959587 0.849186725 1 11.00544047 -6.987559283 23.50198189 0.953396868 1.026953424 0.197536884 0.099329014 192.3028246 363279.1514 0.015698272 0.020621342 1.03E-07 6.987559283 0.073556556 GESENAGTNQET(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 GESENAGTNQETR 13 0 Q08170 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 1 0 GES(0.038)ENAGT(0.086)NQET(0.875)R;GES(0.077)ENAGT(0.11)NQET(0.813)R ; 185.66 0.00016652 23677000 3419.3 2763.6 3057 3038.1 3538.3 3506.3 2517.4 1960.4 2811.8 2999.1 TRUE FALSE FALSE 3148.658797 3002.47327 3170.295109 3025.529147 3496.108083 2779.053856 2588.031469 2558.116935 2503.352575 3103.318502 1.014610262 0.967504066 1.021582254 0.974933493 1.126570825 0.895510356 0.833956124 0.824316593 0.806669561 1 11.59959606 -5.038591466 6.881288764 1.009803148 0.837096817 0.395629297 0.076392866 0.064009065 9.164712002 0.005325083 0.014077724 9.15E-06 5.038591466 -0.172706331 GESENAGTNQETR ddPTM_HeLa_Curcumin_4h_R1 2 GESENAGTNQETR 13 0 Q08170 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 0 0 ; ; 170.04 6.50E-06 1083320 0 0 0 0 76.509 0 0 0 61.111 0 FALSE FALSE TRUE 0 0 0 0 75.59668014 0 0 0 54.40727619 0 0 GESLDNLDS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 GESLDNLDSPR 11 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 GESLDNLDS(1)PR;GESLDNLDS(1)PR;GESLDNLDS(1)PR ;; 170 0.00024108 64560700 6653.2 6461.47 5500.6 6353.9 6338.1 9011.2 8065.5 4082.97 6711.7 6125.1 TRUE FALSE FALSE 6126.5922 7019.970675 5704.457075 6327.609245 6262.522297 7142.175543 8291.796223 5327.848757 5975.443302 6337.946769 0.966652517 1.107609598 0.90004812 0.998368948 0.988099542 1.126891058 1.308277984 0.840626934 0.942804274 1 12.62979983 -5.265408818 23.10371684 0.98823366 1.1135666 0.138206675 0.117211005 131.5136444 765474.1958 0.014737039 0.034183394 5.43E-06 5.265408818 0.12533294 GESS(ph)SPSPSAEK ddPTM_HeLa_Curcumin_4h_R1 1 GESSSPSPSAEK 12 0 E9PHV5;P28290-3;P28290;P28290-2 E9PHV5 SSFA2 Sperm-specific antigen 2 1 0 GES(0.004)S(0.582)S(0.368)PS(0.046)PSAEK 121.21 0.0034419 7842100 3475.4 3764.5 3696.2 3616.1 3548.3 3173.8 1917.6 1255.7 3067.7 2749.2 TRUE FALSE FALSE 3200.318423 4089.886606 3833.184424 3601.137536 3505.98884 2515.518104 1971.402695 1638.557149 2731.180985 2844.734495 1.124997228 1.437704156 1.347466496 1.26589583 1.232448528 0.884271663 0.693000594 0.575996513 0.960082914 1 11.47407829 -4.925133223 2.505004329 1.137043094 0.614895343 0.693223456 0.148046619 0.154067319 1.90693067 0.02486834 0.096815258 1.19E-05 4.925133223 -0.522147752 GESSS(ph)PSPSAEK ddPTM_HeLa_Curcumin_4h_R1 1 GESSSPSPSAEK 12 0 E9PHV5;P28290-3;P28290;P28290-2 E9PHV5 SSFA2 Sperm-specific antigen 2 1 0 GESS(0.051)S(0.941)PS(0.003)PS(0.003)AEK 107.17 0.0064223 8169400 11331 10103 10736 9599 10353 8736.4 4928.7 3612.4 8194.7 7771 TRUE FALSE FALSE 10434.13939 10976.2583 11133.8856 9559.281881 10229.54724 6924.37216 5066.986057 4713.804131 7295.761912 8041.041672 1.297610412 1.365029402 1.384632248 1.188811384 1.272166922 0.86112875 0.630140505 0.586218095 0.907315521 1 12.97316669 -5.011962498 2.766690499 1.190823009 0.605119415 0.737310449 0.144153984 0.111612674 1.700367908 0.022444046 0.075899066 9.73E-06 5.011962498 -0.585703594 GEVAPDAK ddPTM_HeLa_Curcumin_4h_R1 1 GEVAPDAK 8 0 P09382;F8WEI7 P09382 LGALS1 Galectin-1 0 0 98.392 0.010491 0 2491 5609.7 2020.3 2407.8 1800.2 2428.5 1764.7 2086.7 1884.7 2646.5 FALSE FALSE TRUE 2293.834722 6094.577472 2095.174095 2397.837162 1778.733791 1924.801725 1814.212733 2722.925224 1677.953125 2738.465678 0.837635009 2.225544589 0.765090507 0.87561337 0.649536638 0.702875972 0.662492412 0.994325124 0.612734766 1 11.41915208 GEVDGEPELDISPCQQWGEAS(ph)SPISR ddPTM_HeLa_Curcumin_4h_R1 1 GEVDGEPELDISPCQQWGEASSPISR 26 0 Q16600 Q16600 ZNF239 Zinc finger protein 239 1 0 GEVDGEPELDISPCQQWGEAS(0.497)S(0.497)PIS(0.006)R 71.143 0.00076612 0 808.1 526.68 646.04 697.42 687.27 1116.5 759.53 595.97 635.36 590.9 TRUE FALSE FALSE 744.1380323 572.2038724 669.9828107 694.5342608 679.0747541 884.9253145 780.8403676 777.6785095 565.6625976 611.433731 1.217037914 0.935839558 1.095757033 1.135910935 1.110626908 1.447295544 1.277064591 1.271893371 0.925141301 1 9.256052333 -5.347091822 7.485904656 1.093949625 1.326059372 0.597062042 0.099722803 0.162057012 12.48809644 0.014470969 0.032507473 4.50E-06 5.347091822 0.232109747 GEVLGLSSS(ph)LGK ddPTM_HeLa_Curcumin_4h_R1 2 GEVLGLSSSLGK 12 0 F1LLU8;Q9NQG7-2;Q9NQG7-3;Q9NQG7;Q9NQG7-4 F1LLU8 HPS4 Hermansky-Pudlak syndrome 4 protein 1 0 GEVLGLS(0.001)S(0.156)S(0.842)LGK;GEVLGLS(0.004)S(0.146)S(0.85)LGK ; 147.71 2.90E-05 0 5969.6 5126.1 5300 5329.4 5614.9 6790.1 4141.4 3567.3 6141.2 5203 TRUE FALSE FALSE 5497.099861 5569.177243 5496.422662 5307.348355 5547.945985 5381.75672 4257.596538 4654.953348 5467.525725 5383.803863 1.021043857 1.034431674 1.020918073 0.98579898 1.030488132 0.999619759 0.790815685 0.864621644 1.015550689 1 12.39441014 -4.772407378 21.66023032 1.01186074 0.827718701 0.921066375 0.021748108 6.098281314 12043.97794 0.002805717 0.008578082 1.69E-05 4.772407378 -0.184142038 GEVPGGSAHYGGPS(ph)PEKK ddPTM_HeLa_Curcumin_4h_R1 1 GEVPGGSAHYGGPSPEKK 18 1 J3KS37;O94762-4;O94762 J3KS37 RECQL5 ATP-dependent DNA helicase Q5 1 0 GEVPGGS(0.102)AHY(0.047)GGPS(0.852)PEKK 86.959 0.0018464 5833500 2357.9 1898.7 1811.9 1615.9 3223.3 4540.1 2046.2 998.76 3551.3 1799.7 TRUE FALSE FALSE 2171.269727 2062.815168 1879.050608 1609.213834 3184.864253 3598.432083 2103.610865 1303.277326 3161.731275 1862.239441 1.165945517 1.107706733 1.009027393 0.864128317 1.710233487 1.932314397 1.129613528 0.699844122 1.697811358 1 10.86282287 -5.774729165 24.99909239 1.063465445 1.391281823 0.057708317 0.374510889 291.8334576 548960.8232 0.048109775 0.087569801 1.68E-06 5.774729165 0.327816378 GEVQVSDKER ddPTM_HeLa_Curcumin_4h_R1 3 GEVQVSDKER 10 1 Q9Y3A5;A0A087X020 Q9Y3A5 SBDS Ribosome maturation protein SBDS 0 0 ;; ;; 123.96 0.0011221 7150000 4566 3212.29 3428.6 3622.82 4312 5481 4167.46 3559.22 4740.3 4522.2 FALSE FALSE TRUE 4204.596282 3489.946034 3555.666932 3607.829731 4260.582216 4344.178816 4284.387711 4644.409793 4220.30095 4679.346113 0.898543553 0.74581917 0.759864059 0.771011514 0.910508031 0.928373049 0.915595386 0.992533931 0.90189972 1 12.19209123 -8.386393593 1.128610762 0.983147825 0.861905286 0.12217572 0.082044902 0.430531566 1.120719429 0.026299186 0.017340738 4.11E-09 8.386393593 -0.121242539 GEWFLLGSPGS(ph) ddPTM_HeLa_Curcumin_4h_R1 1 GEWFLLGSPGS 11 0 H0Y7V3;H0Y746;Q96T76-5;Q96T76-9;Q96T76;Q96T76-8 H0Y7V3 MMS19 MMS19 nucleotide excision repair protein homolog 1 0 GEWFLLGS(0.144)PGS(0.856) 101.3 0.0103 2109400 1182.8 944.77 945.91 897.12 844.62 1043.6 843.96 789.52 1330.7 1079.5 TRUE FALSE FALSE 1089.180132 1026.431709 980.9662567 893.4079551 834.5484581 827.1455962 867.6392462 1030.241013 1184.725539 1117.012545 0.975083169 0.918907951 0.878205228 0.799819088 0.747125412 0.740498037 0.776749778 0.922318212 1.060619726 1 10.12542967 -6.730020015 1.360622644 0.989781785 0.788876418 0.751464838 0.053121462 0.13506866 0.504203768 0.008600756 0.012977817 1.86E-07 6.730020015 -0.200905367 GEYDVTMPK ddPTM_HeLa_Curcumin_4h_R1 2 GEYDVTMPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 131.22 0.00055208 4329900 5103.3 4641.5 4592.8 5408.3 5015.5 4063.2 3588.8 3152.7 5141.3 4545.2 FALSE FALSE TRUE 4699.36842 5042.690578 4763.013208 5385.921888 4955.693438 3220.446518 3689.492069 4113.943717 4577.312253 4703.145362 0.999196933 1.072195348 1.012729321 1.145174447 1.053697697 0.684743139 0.784473323 0.874721787 0.973244903 1 12.19941021 -5.270934517 24.999608 1.020519895 0.781628805 0.76911659 0.063672971 237.0982059 624252.5883 0.009255112 0.020953262 5.36E-06 5.270934517 -0.238891089 GEYQESLRS(ph)LEEEGQELPQSADVQR ddPTM_HeLa_Curcumin_4h_R1 2 GEYQESLRSLEEEGQELPQSADVQR 25 1 P48681 P48681 NES Nestin 1 0 GEY(0.001)QES(0.041)LRS(0.957)LEEEGQELPQSADVQR;GEY(0.006)QES(0.046)LRS(0.948)LEEEGQELPQSADVQR ; 118.08 1.08E-08 16642700 1031.22 655.49 751.58 858.89 850.7 842.73 790.53 851.9 692.71 689.32 TRUE FALSE FALSE 949.5978489 712.1476348 779.434216 855.3361408 840.5559581 667.9382985 812.7101442 1111.640388 616.7214461 713.2738187 1.331323012 0.998421106 1.092755959 1.199169405 1.178447794 0.93644023 1.139408349 1.558504405 0.864634913 1 9.478312209 -4.262115654 7.904346772 1.13325726 1.562096981 0.482203862 0.139318512 0.065692355 48.38011048 0.019311592 0.151620695 5.47E-05 4.262115654 0.428839721 GFAFVTFDDHDSVDK ddPTM_HeLa_Curcumin_4h_R1 3 GFAFVTFDDHDSVDK 15 0 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8VZ49;A0A2R8Y4L2;H0YH80;Q32P51 F8W6I7 HNRNPA1;HNRNPA1L2 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;Heterogeneous nuclear ribonucleoprotein A1-like 2" 0 0 ;; ;; 110.55 0.0017338 19699570 4835.2 3946.4 4008.1 3627.95 5925 11108.8 5484.7 4800.85 5799.3 4135.09 FALSE FALSE TRUE 4452.488818 4287.509231 4156.643712 3612.938504 5854.348245 8804.709658 5638.585921 6264.607065 5163.131299 4278.78407 1.040596755 1.002039168 0.971454424 0.844384396 1.368227083 2.057759755 1.317800999 1.464109187 1.206681902 1 12.06298516 -5.568647808 5.722898947 1.005175173 1.604599472 0.663760633 0.194367391 0.072937637 5.630410057 0.025149259 0.051353296 2.70E-06 5.568647808 0.5994243 GFAFVTFDDHDTVDK ddPTM_HeLa_Curcumin_4h_R1 2 GFAFVTFDDHDTVDK 15 0 P51991;P51991-2 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 0 ; ; 201.08 3.11E-31 25749000 5009.3 4357.1 3946.8 3849 5874.3 8860.4 6289.1 4900.8 5436.5 4216.9 FALSE FALSE TRUE 4612.808619 4733.708309 4093.07188 3833.073858 5804.252809 7022.653163 6465.55522 6395.031359 4840.129551 4363.436961 1.057150283 1.084857728 0.938038504 0.878452901 1.330202054 1.609431562 1.481757449 1.465594992 1.109247044 1 12.09124924 -5.577347866 4.638897754 1.016492639 1.51059472 0.906902489 0.07400161 0.039672266 1.791280177 0.010341073 0.02146304 2.65E-06 5.577347866 0.494102081 GFAFVTFES(ph)PADAK ddPTM_HeLa_Curcumin_4h_R1 2 GFAFVTFESPADAK 14 0 P38159;Q96E39;H0Y6E7;H3BT71;A0A1B0GUK8;H3BR27;P38159-3;O75526;Q8N7X1 P38159 RBMX;RBMXL1;RBMXL2;RBMXL3 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1;RNA-binding motif protein, X-linked-like-2;RNA-binding motif protein, X-linked-like-3" 1 0 GFAFVTFES(1)PADAK;GFAFVT(0.001)FES(0.999)PADAK ; 146.59 0.00059976 58509000 11208 9489.3 9855.8 10551.7 11639.9 15501.3 13453.9 9739.2 10723 9606.6 TRUE FALSE FALSE 10320.87497 10309.51281 10221.06462 10508.03986 11501.10179 12286.15564 13831.38022 12708.63725 9546.713728 9940.428635 1.038272629 1.037129603 1.028231779 1.057101283 1.157002602 1.235978457 1.391426943 1.278479803 0.960392562 1 13.27909235 -5.38946911 1.343775698 1.020278271 1.340166738 0.921912833 0.037426518 0.07026617 0.237709629 0.004765933 0.017109028 4.08E-06 5.38946911 0.319888466 GFAYVQFEDVRDAEDALHNLDR ddPTM_HeLa_Curcumin_4h_R1 1 GFAYVQFEDVRDAEDALHNLDR 22 1 Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3;O75494-2;O75494 Q5JRI1 SRSF10 Serine/arginine-rich splicing factor 10 0 0 95.429 9.84E-05 3825300 671.97 721.43 641.84 488.58 466.54 1386 959.71 854.57 811.25 640.58 FALSE FALSE TRUE 618.7828654 783.7871946 665.627155 486.5583854 460.9768152 1098.527977 986.6368797 1115.124459 722.2579046 662.8401073 0.933532625 1.182467968 1.004204706 0.734050912 0.695457034 1.657304627 1.488499065 1.682343067 1.089641222 1 9.37251709 -5.25037356 24.92148511 0.95332409 1.597293995 0.811092173 0.146114906 220.2301598 495982.2256 0.020333116 0.051296432 5.62E-06 5.25037356 0.643969904 GFCFLEYEDHK ddPTM_HeLa_Curcumin_4h_R1 4 GFCFLEYEDHK 11 0 O60506-4;O60506-3;O60506-2;O60506;B7Z645;O60506-5;O43390;B4DT28;O43390-4;O43390-3;O43390-2 O60506-4;O43390 SYNCRIP;HNRNPR Heterogeneous nuclear ribonucleoprotein Q;Heterogeneous nuclear ribonucleoprotein R 0 0 ;;; ;;; 138.25 0.00070359 290376600 15527.2 11251.5 14491.8 13369.1 13054.8 16147.5 13257.2 10823.1 14844.2 11386.4 FALSE FALSE TRUE 14298.20574 12224.02952 15028.87886 13313.78221 12899.13004 12798.32648 13629.16135 14123.01337 13215.8284 11782.07655 1.213555664 1.037510618 1.275571313 1.13000303 1.094809559 1.086253889 1.156770735 1.198686268 1.121689232 1 13.52430621 -9.477336603 1.16471867 0.998338508 1.152399361 0.105282446 0.074636113 0.373435868 0.890417293 0.047157426 0.011057467 3.33E-10 9.477336603 0.154060853 GFDQTINLILDESHER ddPTM_HeLa_Curcumin_4h_R1 2 GFDQTINLILDESHER 16 0 F2Z2Y6;C9JIZ0;C9JNV3;O95777 F2Z2Y6 LSM8 U6 snRNA-associated Sm-like protein LSm8 0 0 ; ; 135.09 0.00034362 9212700 5648.5 4227.5 4258.3 4730.6 4532.3 7166.8 4941.9 5302.6 5672.2 5010.3 FALSE FALSE TRUE 5201.415265 4592.906263 4416.116344 4711.026031 4478.255283 5680.324894 5080.556414 6919.33833 5049.973851 5184.407552 1.003280551 0.885907641 0.851807328 0.908691299 0.863793064 1.095655547 0.979968562 1.33464398 0.974069612 1 12.33996342 -3.297450659 1.376986386 0.969519786 4.738909077 0.70043514 0.074049801 7.680572065 1.602285527 0.011829115 74.5080361 0.000504138 3.297450659 3.769389291 SLS(ph)EQPVMDTATATEQAK ddPTM_HeLa_Curcumin_4h_R1 4 SLSEQPVMDTATATEQAK 18 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 0 S(0.016)LS(0.855)EQPVMDT(0.128)ATATEQAK;S(0.006)LS(0.993)EQPVMDTATATEQAK;S(0.082)LS(0.817)EQPVMDT(0.03)AT(0.067)AT(0.003)EQAK;S(0.041)LS(0.959)EQPVMDTATATEQAK ;;; 185.28 3.14E-07 199719000 7174.8 5066.87 6678.5 7539.8 5891.9 6804.1 9037.7 72911 4916.4 5984.5 TRUE FALSE FALSE 6606.907009 5504.827665 6926.011085 7508.602305 5821.642941 5392.852962 9291.273538 95141.22826 4377.08322 6192.46093 1.066927524 0.888956382 1.118458584 1.21253931 0.940117831 0.870873958 1.500416982 15.36404175 0.706840668 1 12.59629715 -4.261285162 5.63414466 1.030345605 15.84754578 0.998910102 0.142088925 0.002209041 0.285208765 0.014095769 0.125297973 5.48E-05 4.261285162 14.81720018 up LPS(ph)GSGAAS(ph)PTGSAVDIR ddPTM_HeLa_Curcumin_4h_R1 4 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 LPS(0.998)GS(0.002)GAAS(0.906)PT(0.038)GS(0.056)AVDIR;LPS(0.993)GS(0.007)GAAS(0.958)PT(0.034)GS(0.008)AVDIR;LPS(0.885)GS(0.115)GAAS(0.985)PT(0.012)GS(0.003)AVDIR;LPS(1)GSGAAS(0.987)PT(0.008)GS(0.005)AVDIR ;;; 183.71 1.01E-06 648294000 4897.49 4273.81 4369.79 5013.06 5124.93 6487.5 7629.7 83262 1281.3 5689.83 TRUE FALSE FALSE 4509.848499 4643.219093 4531.738261 4992.317286 5063.818557 5141.919371 7843.768848 108648.2005 1140.744596 5887.551169 0.765997334 0.788650316 0.769715308 0.847944611 0.860089095 0.873354511 1.332263385 18.45388641 0.19375536 1 12.52345198 -4.261279056 5.992863545 0.872596787 18.93189033 0.998191436 0.225183281 0.00181463 0.310715239 0.015386568 0.13279032 5.48E-05 4.261279056 18.05929354 up GFENVIHDKLPLQES(ph)EEEEREER ddPTM_HeLa_Curcumin_4h_R1 2 GFENVIHDKLPLQESEEEEREER 23 2 P23497;E9PHV6;P23497-7;P23497-6;P23497-2;P23497-3;P23497-4;P23497-5;C9JBL0 P23497 SP100 Nuclear autoantigen Sp-100 1 0 GFENVIHDKLPLQES(1)EEEEREER;GFENVIHDKLPLQES(1)EEEEREER ; 54.049 0.003679 21990400 8672.5 7332 7102.8 7871.8 7307.9 10733.3 7925.5 5734 9136.5 7428.7 TRUE FALSE FALSE 7986.062474 7965.745409 7366.036016 7839.228577 7220.758065 8507.092591 8147.8682 7482.270204 8134.248808 7686.846772 1.038925675 1.036282581 0.958264973 1.019823708 0.939365422 1.10670771 1.059975363 0.973386152 1.058203585 1 12.9081762 GFFDPNTHENLTYLQLLER ddPTM_HeLa_Curcumin_4h_R1 2 GFFDPNTHENLTYLQLLER 19 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4;A0A075B730;P58107 Q15149;Q15149-3;Q15149-4;A0A075B730 PLEC;EPPK1 Plectin;Epiplakin 0 0 ; ; 185.71 8.50E-08 62482000 3156.9 2766.43 2678.32 2636.96 2871.1 5937.6 4388.6 3193.6 3046.2 2860.5 FALSE FALSE TRUE 2907.028034 3005.547882 2777.580895 2626.048958 2836.864008 4706.074829 4511.732305 4167.313938 2712.039481 2959.902162 0.982136528 1.015421361 0.938402941 0.887208027 0.958431682 1.589942698 1.524284269 1.407922867 0.91625984 1 11.53133377 -5.265397937 24.99907981 0.979190029 1.509073391 0.950062153 0.057682329 47.63488062 300824.813 0.007920288 0.018344406 5.43E-06 5.265397937 0.529883363 GFFDPNTHENLTYR ddPTM_HeLa_Curcumin_4h_R1 2 GFFDPNTHENLTYR 14 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 149.57 0.00041793 56146000 4906.9 4253.3 4940.1 5192 4685 5933.1 4949.8 4063 4772.6 4680.9 FALSE FALSE TRUE 4518.513687 4620.9363 5123.184452 5170.51688 4629.134435 4702.50818 5088.678066 5301.789996 4249.05772 4843.560927 0.932890854 0.954036993 1.057730981 1.067503219 0.955729577 0.970878296 1.050606804 1.094605823 0.877259063 1 12.24185237 -6.77083515 24.99295813 0.966353655 1.028903728 0.401659338 0.051158102 195.0092435 518727.6224 0.007831817 0.010369728 1.69E-07 6.77083515 0.062550073 GFFDPNTHENLTYVQLLR ddPTM_HeLa_Curcumin_4h_R1 2 GFFDPNTHENLTYVQLLR 18 0 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 0 0 ; ; 77.027 0.0065244 22075000 3045.5 2257.3 2999.3 2520.2 2495 7558 4554.4 2701.9 3556.3 3038.9 FALSE FALSE TRUE 2804.445461 2452.410954 3110.456696 2509.77208 2465.248755 5990.385604 4682.184206 3525.696872 3166.182787 3144.501549 0.891856918 0.779904514 0.989173212 0.798146238 0.783987133 1.90503503 1.489006806 1.121225993 1.006894968 1 11.61861563 -5.278632247 24.99994615 0.916813103 1.503481057 0.673910458 0.19466287 337.5665218 490851.018 0.026824685 0.060115667 5.26E-06 5.278632247 0.586667955 GFGDGYNGYGGGPGGGNFGGS(ph)PGYGGGR ddPTM_HeLa_Curcumin_4h_R1 4 GFGDGYNGYGGGPGGGNFGGSPGYGGGR 28 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 0 GFGDGYNGYGGGPGGGNFGGS(1)PGYGGGR;GFGDGYNGY(0.026)GGGPGGGNFGGS(0.948)PGY(0.026)GGGR;GFGDGYNGYGGGPGGGNFGGS(0.999)PGY(0.001)GGGR;GFGDGYNGY(0.007)GGGPGGGNFGGS(0.993)PGYGGGR ;;; 126.76 1.32E-10 299466000 17484.4 14465.7 15297.4 15858.3 14875.1 21994.7 16277.3 7958.9 16898.5 13697.1 TRUE FALSE FALSE 16100.49129 15716.05065 15864.3351 15792.68256 14697.72415 17432.75129 16733.99723 10385.53197 15044.77683 14173.07321 1.135991542 1.108866822 1.119329229 1.114273688 1.037017444 1.229990916 1.180689395 0.732764999 1.061504207 1 13.790865 -2.008037176 16.11328933 1.075105927 0.379872356 0 0.129594695 0 0 0.016169894 0 0.009816639 2.008037176 -0.695233571 GFGFGQGAGALVHS(ph)E ddPTM_HeLa_Curcumin_4h_R1 4 GFGFGQGAGALVHSE 15 0 E9PP21;P21291 E9PP21 CSRP1 Cysteine and glycine-rich protein 1 1 0 GFGFGQGAGALVHS(1)E;GFGFGQGAGALVHS(1)E;GFGFGQGAGALVHS(1)E;GFGFGQGAGALVHS(1)E ;;; 144.51 0.00049678 1568429000 28643.1 24701.8 25229 27814.3 25214.3 29921.5 20640.6 12723.1 31267 26903.7 TRUE FALSE FALSE 26375.96841 26836.91352 26164.00893 27699.2118 24913.63594 23715.44362 21219.71968 16602.31462 27837.08833 27838.60157 0.94746025 0.964018018 0.939846381 0.994992932 0.894931302 0.851890622 0.762240863 0.596377464 0.999945642 1 14.76479912 -3.686505297 0.635029522 0.975868084 2.20E-16 0.964901532 0.022962096 0.781590567 0.130193955 0.004380581 0.655823361 0.000205823 3.686505297 -0.975868084 GFGFGQGAGALVHSE ddPTM_HeLa_Curcumin_4h_R1 1 GFGFGQGAGALVHSE 15 0 E9PP21;P21291 E9PP21 CSRP1 Cysteine and glycine-rich protein 1 0 0 93.442 0.013654 6998400 2882.4 2280.2 2380.5 2402.1 2515.4 3144.5 2430.7 2873.6 2984 2580.9 FALSE FALSE TRUE 2654.254999 2477.290328 2468.723424 2392.160747 2485.405498 2492.295254 2498.8989 3749.747412 2656.662666 2670.586083 0.993884831 0.927620474 0.9244126 0.895743733 0.930659196 0.933239063 0.935711796 1.404091572 0.994786381 1 11.38294067 -4.258768508 24.98082673 0.969062708 1.404091729 0.923355491 0.038977145 61.0807781 571259.1328 0.006866338 0.063235334 5.51E-05 4.258768508 0.435029021 GFGFVDFNSEEDAK ddPTM_HeLa_Curcumin_4h_R1 4 GFGFVDFNSEEDAK 14 0 P19338;H7BY16 P19338 NCL Nucleolin 0 0 ;;; ;;; 200.93 1.40E-13 93080880 5959.52 4516.33 5335.38 5695.32 5312.53 5945.27 4723.69 4628.52 5864.82 5122.5 FALSE FALSE TRUE 5487.817704 4906.701441 5533.113876 5671.754275 5249.181549 4712.153985 4856.224028 6039.734441 5221.463919 5300.506494 1.035338361 0.92570426 1.043883992 1.070040058 0.990316974 0.8890007 0.91618113 1.139463643 0.985087732 1 12.37191451 -5.526009154 24.99095632 1.015698414 0.9691196 0.02003588 0.071870845 179.3121775 1431500.348 0.009845899 0.019771249 2.98E-06 5.526009154 -0.046578814 GFGFVEFEDPRDADDAVYELDGK ddPTM_HeLa_Curcumin_4h_R1 2 GFGFVEFEDPRDADDAVYELDGK 23 1 G3V5K8;B4DJK0;B4DUA4;Q13243-2;Q13243 G3V5K8 SRSF5 Serine/arginine-rich splicing factor 5 0 0 ; ; 101.48 3.96E-05 24243000 5593.5 4733.9 5111.2 4490 5009.4 7427.1 5955.8 5585.2 5737.4 4850 FALSE FALSE TRUE 5150.768573 5143.077222 5300.625568 4471.42157 4949.666177 5886.635739 6122.903719 7288.101769 5108.021574 5018.537139 1.026348601 1.024816013 1.056209294 0.890981066 0.986276686 1.172978415 1.220057469 1.452236293 1.017830781 1 12.29305118 -4.494578502 1.251963576 1.006877919 1.534183376 0.882581933 0.051725126 0.231011433 0.406109926 0.007709598 0.139739894 3.20E-05 4.494578502 0.527305456 GFGFVTFDDHDPVDK ddPTM_HeLa_Curcumin_4h_R1 3 GFGFVTFDDHDPVDK 15 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 ;; ;; 153.14 0.00032584 578788400 10820.6 8714.5 9939.4 8216.5 8993.3 13783.6 11495.5 10374.9 8324.9 7086.08 FALSE FALSE TRUE 9964.138092 9467.742549 10307.76291 8182.5023 8886.060771 10924.72599 11818.03279 13538.15925 7411.679298 7332.320753 1.358933744 1.291234095 1.405798144 1.115949858 1.211902898 1.489941092 1.611772478 1.84636757 1.010823114 1 12.84005418 -1 0.304978833 1.138671208 7.167470203 0.753006786 0.126711792 22.66793217 0.289928218 0.056615953 76.0253772 0.1 1 6.028798995 GFGFVTFDDHDPVDKIVLQK ddPTM_HeLa_Curcumin_4h_R1 2 GFGFVTFDDHDPVDKIVLQK 20 1 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 ; ; 118.71 5.72E-05 63352000 9318.7 6303.1 7361.6 5779.8 4643.3 16785.7 10168.4 11181.2 11350.1 9601.8 FALSE FALSE TRUE 8581.115062 6847.911878 7634.427372 5755.884719 4587.93168 13304.15661 10453.69794 14590.29641 10105.02243 9935.461835 0.863685574 0.689239412 0.768401862 0.579327344 0.461773369 1.339057693 1.052160243 1.468507116 1.017066201 1 13.27837132 -5.227913407 24.97990668 0.847683327 1.26313364 0.566213082 0.199231297 461.2955193 343706.6227 0.030540418 0.077858216 5.92E-06 5.227913407 0.415450313 GFGFVTYATVEEVDAAMNARPHK ddPTM_HeLa_Curcumin_4h_R1 1 GFGFVTYATVEEVDAAMNARPHK 23 1 F8W6I7;P09651-2;P09651;P09651-3;F8VZ49;A0A2R8Y4L2;F8VYN5;F8W646 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 0 0 132.14 4.58E-06 22102000 3078.3 2480 2451 3038.4 2107.6 4039.7 2806.6 3041.6 3325.4 2921.6 FALSE FALSE TRUE 2834.649307 2694.360149 2541.836216 3025.827906 2082.468247 3201.820683 2885.345642 3968.969838 2960.61194 3023.125383 0.937655224 0.891249885 0.840797484 1.00089395 0.688846139 1.059109457 0.954424735 1.312869741 0.979321584 1 11.5618251 -4.048095956 2.06866596 0.941647978 1.611525962 0.566306973 0.099994244 0.925893776 2.517992579 0.01366249 1.421839666 8.95E-05 4.048095956 0.669877984 VVQPQEEIATK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VVQPQEEIATKK 12 1 E9PIM3;F8WAA7;Q96HW7-2;Q96HW7 E9PIM3 INTS4 Integrator complex subunit 4 0 1 ; VVQPQEEIATK(1)K;VVQPQEEIATK(1)K 223.08 1.94E-29 31153000 7545.7 6745.1 7179.1 6781.1 6403.5 9698.5 9407.1 11943.3 7250.7 7076.6 FALSE TRUE FALSE 6948.449883 7328.116388 7445.163761 6753.041605 6327.142445 7686.921775 9671.037908 15584.75719 6455.31635 7322.511323 0.948916236 1.000765457 1.016750051 0.922230271 0.86406728 1.049765775 1.320726931 2.128335007 0.881571372 1 12.8381228 -4.231237194 1.772758778 0.969534999 2.577524189 0.978088625 0.053196912 0.088199852 0.256792404 0.007072032 0.243044751 5.87E-05 4.231237194 1.60798919 up GFGGPYCVPVVPLPS(ph)ILK ddPTM_HeLa_Curcumin_4h_R1 1 GFGGPYCVPVVPLPSILK 18 0 J3KQ66;P78509-3;P78509-2;P78509 J3KQ66 RELN Reelin 1 0 GFGGPYCVPVVPLPS(1)ILK 54.74 0.018043 33509000 1904.9 1467.4 1326.9 1539.7 1377.4 1982.7 1770.3 1387.9 1813 1429 TRUE FALSE FALSE 1754.125155 1594.235517 1376.076081 1533.329129 1360.975405 1571.46567 1819.969853 1811.064321 1614.118436 1478.657644 1.186295667 1.078164053 0.930625211 1.036973728 0.920412788 1.062765054 1.230825716 1.224803002 1.091610653 1 10.53007235 -4.762559219 22.93582781 1.060827131 1.227814459 0.479529091 0.076124958 8.612723937 176470.1004 0.013526476 0.044294743 1.73E-05 4.762559219 0.166987328 GFGLEGVPEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 GFGLEGVPEKR 11 1 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 0 1 GFGLEGVPEK(1)R 136.63 0.00011532 7157800 2880.9 3251.8 3279.5 2867.7 2615.1 3810 2073.6 1797.6 2789.2 2508.6 FALSE TRUE FALSE 2652.873725 3532.871102 3401.041155 2855.834217 2583.91664 3019.763052 2131.779635 2345.679965 2483.231738 2595.773663 1.021997319 1.361008917 1.310222537 1.100186144 0.995432182 1.163338351 0.821250198 0.903653503 0.956644169 1 11.34194888 -4.752648642 24.98569274 1.070595821 0.862451781 0.322885429 0.134392276 206.4055637 586647.576 0.020576576 0.074690433 1.77E-05 4.752648642 -0.20814404 GFGS(ph)EEGSR ddPTM_HeLa_Curcumin_4h_R1 1 GFGSEEGSR 9 0 Q9Y5S9 Q9Y5S9 RBM8A RNA-binding protein 8A 1 0 GFGS(0.999)EEGS(0.001)R 97.597 0.014539 220740000 2832.1 2457.2 2540.3 2563.5 2616.2 2825.8 2400.1 2152.6 2784.6 2328.2 TRUE FALSE FALSE 2607.936297 2669.589419 2634.445753 2552.892916 2585.003524 2239.697227 2467.440346 2808.917831 2479.136347 2409.104777 1.082533363 1.108125078 1.093537225 1.059685299 1.073014154 0.92968029 1.024214625 1.16595918 1.029069541 1 11.23428143 -4.255724422 24.23949912 1.043573543 1.165959261 0.349183175 0.049762374 401.5902488 1703229.991 0.007670142 0.089340472 5.55E-05 4.255724422 0.122385718 GFGSEEGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 GFGSEEGSR 9 0 Q9Y5S9 Q9Y5S9 RBM8A RNA-binding protein 8A 1 0 GFGS(0.323)EEGS(0.677)R;GFGS(0.499)EEGS(0.501)R ; 122.96 0.0054681 73126000 4357.4 4222.8 4223.1 4055.6 4038.2 5083.6 4451 4171.1 4318.1 4234.9 TRUE FALSE FALSE 4012.507192 4587.800016 4379.611801 4038.819002 3990.047102 4029.204056 4575.883081 5442.849189 3844.415233 4382.06246 0.915666362 1.046949937 0.999440752 0.921670797 0.910540901 0.919476638 1.044230456 1.242074762 0.877307265 1 12.09739433 -4.333884832 2.791034904 0.960098388 1.271620562 0.753499171 0.050643068 0.131854126 1.518852091 0.00690334 0.08567223 4.64E-05 4.333884832 0.311522174 GFGSEEGSR ddPTM_HeLa_Curcumin_4h_R1 2 GFGSEEGSR 9 0 Q9Y5S9 Q9Y5S9 RBM8A RNA-binding protein 8A 0 0 ; ; 125.81 0.00090966 5188000 3185.3 2464.8 2704.4 2572.2 2815.9 3593.6 2783 2613.9 3375.2 2426 FALSE FALSE TRUE 2933.180144 2677.846329 2804.627443 2561.556918 2782.322232 2848.246852 2861.08349 3410.866077 3004.949004 2510.303319 1.168456465 1.066742138 1.117246438 1.020417293 1.108360974 1.134622589 1.13973617 1.358746591 1.197046182 1 11.29364598 -1.000000003 0.017027267 4.98E-10 2.525683981 0.099913947 0.090970732 3453.600759 4.58323357 264.4711636 435.5362339 0.099999999 1.000000003 2.52568398 GFIYVHK(ac)PPVHIR ddPTM_HeLa_Curcumin_4h_R1 2 GFIYVHKPPVHIR 13 1 Q08945 Q08945 SSRP1 FACT complex subunit SSRP1 0 1 ; GFIYVHK(1)PPVHIR;GFIYVHK(1)PPVHIR 143.24 6.20E-05 5101800 2687.5 3100.9 2411.64 2599.3 3713.1 6778.6 4546.3 4045.8 4617.2 2906.8 FALSE TRUE FALSE 2474.781539 3368.927979 2501.0175 2588.544785 3668.823708 5372.641949 4673.856942 5279.345795 4110.704712 3007.811084 0.822784899 1.1200597 0.831507508 0.860607503 1.21976534 1.786229853 1.553906416 1.755211896 1.366676496 1 11.55449824 -5.463268192 3.256135313 0.921767358 1.68251564 0.753342684 0.174532042 0.050512319 1.053258323 0.015754887 0.036845146 3.44E-06 5.463268192 0.760748282 GFIYVHKPPVHIR ddPTM_HeLa_Curcumin_4h_R1 2 GFIYVHKPPVHIR 13 1 Q08945 Q08945 SSRP1 FACT complex subunit SSRP1 0 0 ; ; 47.288 0.01487 8736700 4138.6 3203.4 3920.2 3475 3651.9 6936.8 4975.8 4438.2 4064.8 3708.7 FALSE FALSE TRUE 3811.025443 3480.287622 4065.486061 3460.621371 3608.353478 5498.029486 5115.407556 5791.386749 3618.90161 3837.577049 0.993081154 0.906897133 1.059388778 0.90177248 0.940268673 1.432682501 1.332978463 1.509125856 0.943017316 1 11.90598 -5.259280352 24.99891929 0.984009619 1.41573392 0.920807457 0.061790544 34.57665416 400352.0595 0.00796477 0.019263349 5.50E-06 5.259280352 0.431724301 GFKDQIYDIFQK ddPTM_HeLa_Curcumin_4h_R1 2 GFKDQIYDIFQK 12 1 P60842;J3KT12;P60842-2;J3KSZ0;J3KTB5;J3QS69;J3KTN0;J3QL43;J3QR64 P60842 EIF4A1 Eukaryotic initiation factor 4A-I 0 0 ; ; 176.05 0.00012334 21514000 10123.9 7286.3 8446.1 7895.1 7723.4 9790.5 8013.8 7744.4 8668.5 7924.4 FALSE FALSE TRUE 9322.582632 7916.095305 8759.119896 7862.432168 7631.303499 7759.839938 8238.64566 10105.63191 7717.587238 8199.77231 1.13693189 0.965404283 1.068215014 0.958859816 0.93067261 0.946348221 1.004740784 1.232428356 0.94119531 1 13.00136813 -7.241432885 24.83202425 1.064662288 1.008801685 0 0.096221433 1617.710778 2007900.964 0.015723555 0.019244899 5.74E-08 7.241432885 -0.055860603 GFNGCDS(ph)PEPDGEDSLEQSPLLEDK ddPTM_HeLa_Curcumin_4h_R1 2 GFNGCDSPEPDGEDSLEQSPLLEDK 25 0 Q14814-4;Q14814;Q05BX2 Q14814-4 MEF2D Myocyte-specific enhancer factor 2D 1 0 GFNGCDS(0.999)PEPDGEDS(0.001)LEQSPLLEDK;GFNGCDS(0.938)PEPDGEDS(0.059)LEQS(0.002)PLLEDK ; 118.44 1.21E-08 11821500 6289 4995.2 5878.1 5737 6811.9 8640.5 5304.6 3895.7 6225.9 5688.1 TRUE FALSE FALSE 5791.219014 5426.96283 6095.947557 5713.261814 6730.672541 6848.362901 5453.432799 5083.480996 5542.934346 5885.761052 0.98393716 0.922049465 1.035711016 0.97069211 1.143551782 1.163547558 0.926546754 0.863691365 0.941753207 1 12.52301326 GFRS(ph)EVDMFVAQAVLQFLCLKNK ddPTM_HeLa_Curcumin_4h_R1 1 GFRSEVDMFVAQAVLQFLCLKNK 23 2 Q7L5D6-2;Q7L5D6 Q7L5D6-2 GET4 Golgi to ER traffic protein 4 homolog 1 0 GFRS(1)EVDMFVAQAVLQFLCLKNK 42.172 0.015228 16238000 2235.2 2489.1 2526.4 2385.8 2194.5 3180.6 2380.1 2267.4 2674.5 2761.8 TRUE FALSE FALSE 2058.281561 2704.246713 2620.030606 2375.928192 2168.332021 2520.907707 2446.8792 2958.719822 2381.114041 2857.772344 0.720239863 0.946277865 0.91680872 0.831391694 0.758749039 0.882123348 0.856219077 1.035323835 0.833206342 1 11.48067528 -9.693316111 1.580809894 0.999795205 0.843498679 0 0.101172763 0.422651073 1.907900582 0.067955747 0.015135185 2.03E-10 9.693316111 -0.156296527 PIPQTPES(ph)AGNK ddPTM_HeLa_Curcumin_4h_R1 1 PIPQTPESAGNK 12 0 A0A3B3ITD8;P52948-6;P52948-2;P52948-5;P52948;P52948-4;P52948-3 A0A3B3ITD8 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 0 PIPQT(0.189)PES(0.811)AGNK 139.19 0.0012874 8448400 3388.1 2581.1 3501.9 3039.1 3870 3235.2 3444.6 6269.9 2467.8 2228.3 TRUE FALSE FALSE 3119.92831 2804.198783 3631.683495 3026.525009 3823.852778 2564.183052 3541.246205 8181.563647 2197.088514 2305.733259 1.353117624 1.216185251 1.575066622 1.312608472 1.65841073 1.112090066 1.535843832 3.548356522 0.95288061 1 11.17100991 -4.261253638 3.431713088 1.246050107 3.840430172 0.908756801 0.214823862 0.065068922 1.289232425 0.031538921 0.439051233 5.48E-05 4.261253638 2.594380065 up TVIRLPS(ph)GSGAASPT(ph)GSAVDIR ddPTM_HeLa_Curcumin_4h_R1 1 TVIRLPSGSGAASPTGSAVDIR 22 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 T(0.235)VIRLPS(0.579)GS(0.232)GAAS(0.471)PT(0.4)GS(0.083)AVDIR 80.016 0.0036527 7943600 755.82 449.61 576.15 613.65 313.64 788.07 1046.9 10208 0 738.87 TRUE FALSE FALSE 695.9960495 488.472285 597.5026258 611.1108789 309.9000478 624.6153986 1076.273196 13320.37221 0 764.5456775 0.910339395 0.638905299 0.781513314 0.79931245 0.405338827 0.816975907 1.407729097 17.42259828 0 1 9.578458887 -4.261205107 5.628169789 0.870161632 17.98365068 0.995777382 0.325795185 0.003906157 0.501827689 0.02871028 0.255618425 5.48E-05 4.261205107 17.11348905 up GFS(ph)LEELR ddPTM_HeLa_Curcumin_4h_R1 2 GFSLEELR 8 0 P26373;P26373-2;J3QSB4 P26373 RPL13 60S ribosomal protein L13 1 0 GFS(1)LEELR;GFS(1)LEELR ; 109.44 0.011459 7603700 5989.1 5244 4361.3 4579.2 5052.2 8180.5 6786.9 4795.1 6481.6 4341.9 TRUE FALSE FALSE 5515.056415 5697.267993 4522.933615 4560.252484 4991.955815 6483.772087 6977.322148 6257.103916 5770.584696 4492.780702 1.227537416 1.268093943 1.006711414 1.015017822 1.111106049 1.443153476 1.553007505 1.392701832 1.284412723 1 12.13339293 -5.24435061 5.168344988 1.107015036 1.476449492 0.665205703 0.107280845 0.079685675 6.646150698 0.016150063 0.040540257 5.70E-06 5.24435061 0.369434455 GFS(ph)LGS(ph)T(ph)VKS(ph)HT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 GFSLGSTVKSHTK 13 1 F6SPX6;F6X827;Q9H0R5-4;Q9H0R5 F6SPX6 GBP3 Guanylate-binding protein 3 5 0 GFS(1)LGS(1)T(1)VKS(1)HT(1)K 54.09 0.014599 28310000 1823.8 2208.9 1893.1 1972.7 1956 2225 1491.5 1621.9 1942 1848.3 TRUE FALSE FALSE 1679.444306 2399.827473 1963.259951 1964.53749 1932.675978 1763.509919 1533.347476 2116.409844 1728.967459 1912.528287 0.878127825 1.254793191 1.026525968 1.027193952 1.010534584 0.922083051 0.801738456 1.106603159 0.904021901 1 10.90126537 -3.957476198 20.25816589 0.969102894 2.10602885 0.089350098 0.115626927 415.8442254 180346.9924 0.016059361 37034.944 0.000110287 3.957476198 1.136925955 GFS(ph)VVADTPELQR ddPTM_HeLa_Curcumin_4h_R1 2 GFSVVADTPELQR 13 0 C9J9W2;Q14847;Q14847-2;Q14847-3 C9J9W2 LASP1 LIM and SH3 domain protein 1 1 0 GFS(0.807)VVADT(0.193)PELQR;GFS(0.844)VVADT(0.156)PELQR ; 193 6.04E-06 668830000 16205.7 12834.4 13726.5 14938.2 14331.3 22794.1 19720.2 5020.6 14872.2 11097.3 TRUE FALSE FALSE 14923.00174 13943.74835 14235.21617 14876.38969 14160.40861 18066.34672 20273.49574 6551.357828 13240.75687 11482.93035 1.299581317 1.214302266 1.23968497 1.295522069 1.233170295 1.57332198 1.765533285 0.570530137 1.153081702 1 13.48720323 -9.511475313 0.436333981 0.887905987 1.315455034 0.047950914 0.2939633 3.798986339 0.825919219 0.75161843 0.082716378 3.08E-10 9.511475313 0.427549046 NKPRS(ph)PVVELSK ddPTM_HeLa_Curcumin_4h_R1 1 NKPRSPVVELSK 12 2 P25098 P25098 ADRBK1 Beta-adrenergic receptor kinase 1 1 0 NKPRS(1)PVVELSK 55.414 0.01697 68095000 3273.3 2888.7 2971.9 3123 3200 3852.2 3429.2 6935.6 3641.6 3363.5 TRUE FALSE FALSE 3014.214851 3138.386356 3082.041228 3110.077853 3161.84209 3053.210297 3525.414123 9050.232512 3242.125591 3480.381375 0.866058781 0.901736338 0.885546984 0.893602602 0.908475753 0.877263141 1.012939027 2.600356552 0.931543197 1 11.76502969 -4.261167706 4.798725313 0.921552784 2.694093892 0.994546802 0.037395774 0.01271914 0.833749777 0.007599388 0.075042386 5.48E-05 4.261167706 1.772541108 up GFSLEELR ddPTM_HeLa_Curcumin_4h_R1 1 GFSLEELR 8 0 P26373;P26373-2;J3QSB4 P26373 RPL13 60S ribosomal protein L13 0 0 152.47 0.014285 6327800 6838.9 2531.1 5525.9 3351.2 5179 6181.8 5736.9 4273.9 4320.3 4232.4 FALSE FALSE TRUE 6297.593849 2749.877006 5730.694715 3337.333622 5117.243808 4899.624997 5897.861974 5576.992435 3846.373899 4379.475585 1.437978983 0.627900979 1.308534459 0.762039554 1.168460403 1.118769794 1.34670507 1.273438412 0.878272712 1 12.09654241 -13.52238172 0.012002365 0.419593916 1.78253062 0 0.258608799 59227.96248 57.46128196 3863.643143 2750.678706 3.00E-14 13.52238172 1.362936704 GFSQYGVSGS(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 2 GFSQYGVSGSPTK 13 0 Q9NXC5 Q9NXC5 MIOS WD repeat-containing protein mio 1 0 GFS(0.002)QYGVS(0.091)GS(0.88)PT(0.027)K;GFS(0.001)QYGVS(0.397)GS(0.552)PT(0.05)K ; 186.29 4.67E-05 314260000 10526.5 8026 9845.8 9273.7 9030.6 10591.6 9183 6711 10095.8 8985.5 TRUE FALSE FALSE 9693.316417 8719.731677 10210.69401 9235.327887 8922.915993 8394.782768 9440.650265 8757.153006 8988.315998 9297.745456 1.042544826 0.93783291 1.098190315 0.993286806 0.959685984 0.902883695 1.015369835 0.941857684 0.966719947 1 13.18266521 -5.887105746 4.282407538 1.019395252 0.955747256 0.202973682 0.048189776 0.199251139 6.522669585 0.006377626 0.01189382 1.30E-06 5.887105746 -0.063647996 GFSVVADT(ph)PELQR ddPTM_HeLa_Curcumin_4h_R1 2 GFSVVADTPELQR 13 0 C9J9W2;Q14847;Q14847-2;Q14847-3 C9J9W2 LASP1 LIM and SH3 domain protein 1 1 0 GFS(0.001)VVADT(0.999)PELQR;GFS(0.013)VVADT(0.987)PELQR ; 211.83 2.41E-09 663930000 11070.7 9836.5 10207.7 11185.5 10554.2 16275.3 14192.4 3711.5 11350.8 8069 TRUE FALSE FALSE 10194.44241 10686.72323 10586.00634 11139.21736 10428.34806 12899.61932 14590.60055 4843.119264 10105.64564 8349.397149 1.220979459 1.279939502 1.267876728 1.334134329 1.248994134 1.544976133 1.747503477 0.580056162 1.210344347 1 13.02745632 -8.375325022 0.522745807 0.993363318 1.327761711 0.031467872 0.287956599 1.245846347 0.729469126 0.186891421 0.080639759 4.21E-09 8.375325022 0.334398393 GFSVVADTPELQR ddPTM_HeLa_Curcumin_4h_R1 2 GFSVVADTPELQR 13 0 C9J9W2;Q14847;Q14847-2;Q14847-3 C9J9W2 LASP1 LIM and SH3 domain protein 1 0 0 ; ; 134.2 0.00092448 3168100 2136.7 1846.47 2065.49 2265.75 1814.61 2630 1835.89 2182.34 2205.2 1984.86 FALSE FALSE TRUE 1967.57794 2006.070639 2142.038876 2256.374927 1792.971961 2084.508354 1887.400132 2847.72542 1963.295077 2053.833737 0.958002542 0.976744418 1.042946582 1.098616157 0.87298788 1.014935297 0.918964422 1.386541358 0.95591724 1 11.00410368 -4.255799246 24.99346081 0.983764338 1.386541531 0.803958925 0.059906242 185.1038141 820237.2501 0.007691492 0.090502408 5.55E-05 4.255799246 0.402777193 GFTECEMTKS(ph)SPLK ddPTM_HeLa_Curcumin_4h_R1 1 GFTECEMTKSSPLK 14 1 Q9NQW6 Q9NQW6 ANLN Actin-binding protein anillin 1 0 GFT(0.001)ECEMT(0.006)KS(0.833)S(0.16)PLK 69.229 0.014951 490790000 5871.6 4986.1 4373.3 5795.8 5769 7536.1 6879.7 2604.2 6926.4 5697 TRUE FALSE FALSE 5406.856664 5417.076266 4535.378345 5771.818515 5700.208443 5973.027911 7072.725866 3398.208592 6166.591249 5894.970326 0.917198284 0.918931897 0.769364067 0.979109002 0.966961346 1.013241387 1.199789901 0.576458982 1.046076724 1 12.52526884 -9.228725302 1.036531614 0.998748794 0.928933231 0.060252665 0.153946292 1.791307127 3.541160688 0.087684992 0.026050413 5.91E-10 9.228725302 -0.069815562 GFTECEMTKSS(ph)PLK ddPTM_HeLa_Curcumin_4h_R1 1 GFTECEMTKSSPLK 14 1 Q9NQW6 Q9NQW6 ANLN Actin-binding protein anillin 1 0 GFTECEMTKS(0.062)S(0.938)PLK 164.81 0.0020774 96910000 3239.6 2702.4 2420 2953.1 2961 3636.3 3079.4 984.56 2959.1 2598.1 TRUE FALSE FALSE 2983.182242 2935.983414 2509.687329 2940.880855 2925.692009 2882.09039 3165.799676 1284.747812 2634.494133 2688.383782 1.10965639 1.092099809 0.933530155 1.093921513 1.088271708 1.072053183 1.177584725 0.477888544 0.97995463 1 11.39252339 -4.254343717 24.95717845 1.060434579 0.477888268 0.870688423 0.067390669 203.9507962 717326.3973 0.009135902 0.123175165 5.57E-05 4.254343717 -0.582546311 GFTIPEAFR ddPTM_HeLa_Curcumin_4h_R1 2 GFTIPEAFR 9 0 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 0 0 ; ; 130.27 0.00060706 4588800 2578.9 1687.82 2209.7 2055.86 2262.9 3040.2 2352.1 2753.9 2314.5 2098.04 FALSE FALSE TRUE 2374.777344 1833.70764 2291.593426 2047.353396 2235.916395 2409.62825 2418.093596 3593.551433 2060.605141 2170.946734 1.093890194 0.844658052 1.055573308 0.943069383 1.02992688 1.109943516 1.113842895 1.655292309 0.949173514 1 11.08410861 -3.81339084 1.460483999 1.024100134 2.850482502 0.866523019 0.076106669 0.97750669 0.771039353 0.010823994 3.58328928 0.000153677 3.81339084 1.826382368 GFVK(ac)VVK ddPTM_HeLa_Curcumin_4h_R1 2 GFVKVVK 7 1 P46777;A0A2R8Y4A2;R4GNJ2 P46777 RPL5 60S ribosomal protein L5 0 1 ; GFVK(1)VVK;GFVK(1)VVK 122.78 0.0090865 11748700 11970.8 10237.2 10073.1 10519 10440.9 12228.4 10163.8 9650.1 12298.6 9572.5 FALSE TRUE FALSE 11023.29855 11122.05795 10446.41795 10475.47517 10316.39909 9692.091998 10448.96887 12592.37107 10949.47435 9905.143662 1.112886287 1.122856804 1.054645778 1.057579327 1.04151938 0.978490805 1.054903314 1.271296156 1.105433169 1 13.27396218 -9.435473796 1.174169722 1.000135606 1.082752118 0 0.079447849 0.744188508 1.839936921 0.049481873 0.012473473 3.67E-10 9.435473796 0.082616512 GGAAGGALPT(ph)SPGPALGAK ddPTM_HeLa_Curcumin_4h_R1 2 GGAAGGALPTSPGPALGAK 19 0 Q9UPR0 Q9UPR0 PLCL2 Inactive phospholipase C-like protein 2 1 0 GGAAGGALPT(0.5)S(0.5)PGPALGAK;GGAAGGALPT(0.881)S(0.119)PGPALGAK ; 142.57 0.00051048 26973000 8322.7 6955.3 7145.9 7421.6 6610.7 7489.3 4227.1 2896.5 7896.5 7064 TRUE FALSE FALSE 7663.949513 7556.48514 7410.73334 7390.891386 6531.87172 5935.934758 4345.701049 3779.629516 7030.273706 7309.473474 1.048495427 1.03379336 1.013853237 1.011138683 0.893617268 0.812087872 0.594529971 0.517086426 0.961803026 1 12.83555177 -4.88037884 1.049191872 1.025045613 0.449365403 0.973470815 0.029385758 0.069518182 0.107261654 0.00382443 0.034901721 1.32E-05 4.88037884 -0.575680209 GGAEQFMEETER ddPTM_HeLa_Curcumin_4h_R1 6 GGAEQFMEETER 12 0 Q99832-3;Q99832;Q99832-2;Q99832-4 Q99832-3 CCT7 T-complex protein 1 subunit eta 0 0 ;;;;; ;;;;; 222.3 5.25E-13 152232300 12677.6 11350.6 11346.7 12452.3 12547.9 13484.9 9847 9865.4 13620.9 11534.18 FALSE FALSE TRUE 11674.15458 12331.69529 11767.21868 12400.77568 12398.27449 10687.97973 10123.28032 12873.31505 12126.72135 11934.9919 0.978145162 1.033238681 0.985942746 1.039026737 1.038817168 0.895516296 0.848201692 1.078619504 1.016064481 1 13.54290997 -5.259554652 24.96579904 0.999151867 0.931521418 0.210461053 0.059248769 185.7509979 2460499.132 0.007782627 0.018814131 5.50E-06 5.259554652 -0.067630449 GGAGAWLGGPAAS(ph)LSPPKGSSASQGGSK ddPTM_HeLa_Curcumin_4h_R1 1 GGAGAWLGGPAASLSPPKGSSASQGGSK 28 1 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 0 GGAGAWLGGPAAS(0.526)LS(0.453)PPKGS(0.011)S(0.005)AS(0.004)QGGS(0.001)K 50.891 0.006295 36092000 1492.1 1025.4 1397.3 1229.9 1189 1521.3 885.54 805.45 1573.5 1419.9 TRUE FALSE FALSE 1373.998711 1114.031007 1449.085167 1224.811 1174.821952 1205.765231 910.3858691 1051.027997 1400.890987 1469.241419 0.93517559 0.758235503 0.986281184 0.833634952 0.799611239 0.820671957 0.61962987 0.715354184 0.9534791 1 10.52085576 -2.618722115 0.192523193 1.025147708 9.34E-11 0.646341022 0.070794796 10.89884623 0.212128549 0.076943714 2.962844781 0.002405902 2.618722115 -1.025147708 GGAGAWLGGPAASLS(ph)PPKGSSASQGGSK ddPTM_HeLa_Curcumin_4h_R1 1 GGAGAWLGGPAASLSPPKGSSASQGGSK 28 1 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 0 GGAGAWLGGPAAS(0.183)LS(0.808)PPKGS(0.006)S(0.002)ASQGGSK 97.825 5.96E-08 46062000 2891.8 2372.2 2671.6 2540 2406.3 3000.5 2385.2 1420.7 3142.3 3117.5 TRUE FALSE FALSE 2662.910979 2577.242398 2770.611846 2529.490153 2377.606444 2378.162477 2452.122293 1853.86489 2797.597552 3225.832893 0.825495637 0.798938595 0.858882632 0.78413552 0.737051956 0.737224325 0.76015168 0.574693405 0.867248132 1 11.65545599 -6.707285931 0.052889546 1.611278197 1.96E-15 0.688575129 0.058217395 12.9235686 0.395594326 5.481938011 6.429955049 1.96E-07 6.707285931 -1.611278197 GGAGGGPGGAGGGS(ph)GQR ddPTM_HeLa_Curcumin_4h_R1 1 GGAGGGPGGAGGGSGQR 17 0 Q6VY07-2;Q6VY07 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 0 GGAGGGPGGAGGGS(1)GQR 96.673 0.0028097 1128800 200.15 164.99 277.41 367.33 358.25 311.61 180.21 157.57 404.85 198.97 TRUE FALSE FALSE 184.3079163 179.2510004 287.6910586 365.8100858 353.9781027 246.9785734 185.2662076 205.6123676 360.4389679 205.8841927 0.89520188 0.870639936 1.397344084 1.776775968 1.71930685 1.199599494 0.899856396 0.998679719 1.750687914 1 7.685689257 -6.759769512 24.99957505 0.943138829 1.344101225 0 0.3648691 41.6463855 623480.9614 0.046332131 0.06358068 1.74E-07 6.759769512 0.400962396 GGAGVGSMTK ddPTM_HeLa_Curcumin_4h_R1 2 GGAGVGSMTK 10 0 P39019 P39019 RPS19 40S ribosomal protein S19 0 0 ; ; 109.44 0.00042976 6010900 5621.6 3725.6 5374.8 5040.5 5729.2 6269.8 5290.3 4995.1 5396 4723.9 FALSE FALSE TRUE 5176.644428 4047.624263 5573.994816 5019.643747 5660.883032 4969.372805 5438.73158 6518.082995 4804.0723 4888.055173 1.059039688 0.828064357 1.140329767 1.026920435 1.158105388 1.016635989 1.112657568 1.33347165 0.982818755 1 12.25504485 -1.000000068 0.781733411 1.024391413 67.68667564 0.545152753 0.08520907 239.253992 0.848047526 0.012691643 28214.80893 0.099999984 1.000000068 66.66228422 GGALPPAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GGALPPAKR 9 1 E7ETY2;Q13428-6;Q13428-7;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 0 1 ; GGALPPAK(1)R;GGALPPAK(1)R 111.65 0.0010392 9673800 3149.6 2618.6 2816 3261.6 3025.9 3379.3 3533.6 2472.1 3248.4 2855.6 FALSE TRUE FALSE 2900.305837 2844.940116 2920.363437 3248.104363 2989.818119 2678.395087 3632.743306 3225.83191 2892.058647 2954.831887 0.981546818 0.962809467 0.988334886 1.099251831 1.011840346 0.906445845 1.2294247 1.091714193 0.978755732 1 11.52886034 -4.757639176 24.9999999 0.993502256 1.160569455 0.605097593 0.054728043 44.04884743 289766.6365 0.007064787 0.024562363 1.75E-05 4.757639176 0.167067199 GGAPDPSPGATATPGAPAQPS(ph)SPDAR ddPTM_HeLa_Curcumin_4h_R1 1 GGAPDPSPGATATPGAPAQPSSPDAR 26 0 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 0 GGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR 167.17 2.69E-12 22634000 2643.5 2036.9 2481.8 2677.4 2701.1 2297 2208.8 1969.6 2350 1965.7 TRUE FALSE FALSE 2434.264186 2212.96056 2573.777691 2666.321628 2668.891147 1820.576307 2270.772983 2570.121973 2092.210879 2034.007929 1.196782053 1.087980302 1.265372497 1.310870814 1.312134092 0.895068442 1.116403211 1.263575199 1.028614908 1 10.99010959 -9.243202343 0.775591447 0.988897158 1.179808216 0.235364615 0.119804329 0.935535352 0.918410426 0.112609452 0.024822156 5.71E-10 9.243202343 0.190911058 GGAPDPSPGATATPGAPAQPSS(ph)PDARR ddPTM_HeLa_Curcumin_4h_R1 1 GGAPDPSPGATATPGAPAQPSSPDARR 27 1 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 0 GGAPDPSPGATAT(0.004)PGAPAQPS(0.247)S(0.749)PDARR 112.91 1.41E-08 20699000 2213.6 1239.6 1781.3 1973.6 1829.3 1889.9 1956 1659.2 2530.1 1541.1 TRUE FALSE FALSE 2038.391224 1346.7455 1847.316545 1965.433766 1807.486792 1497.913436 2010.880096 2165.082442 2252.55436 1594.65311 1.278266233 0.844538221 1.158444136 1.23251493 1.133467072 0.939334973 1.261014124 1.357713742 1.412567 1 10.63902691 -4.535758799 24.25166621 1.112120731 1.333538921 0.186544204 0.157980813 136.7195752 257428.136 0.019585457 0.073382176 2.91E-05 4.535758799 0.22141819 ELST(ph)SPCNPIVR ddPTM_HeLa_Curcumin_4h_R1 1 ELSTSPCNPIVR 12 0 H3BSS6;Q9H2Y7;H3BNX5 H3BSS6 ZNF106 Zinc finger protein 106 1 0 ELS(0.058)T(0.884)S(0.058)PCNPIVR 223.22 1.98E-13 50323000 4867.5 3689 3799.1 3864 3899.9 3861.7 2232.7 612.6 5079.2 4476.3 TRUE FALSE FALSE 4482.232239 4007.860722 3939.897988 3848.011792 3853.39624 3060.73989 2295.343553 799.3789199 4522.024468 4631.851092 0.967697827 0.865282722 0.850609812 0.830771913 0.831934396 0.660802739 0.495556422 0.172583035 0.976288827 1 12.17737316 -4.611263108 0.669119375 0.972307543 2.49E-28 0.94981418 0.054945262 0.331873378 0.134365815 0.010457149 0.222987145 2.45E-05 4.611263108 -0.972307543 down TSS(ph)EASMDAAYLDK ddPTM_HeLa_Curcumin_4h_R1 1 TSSEASMDAAYLDK 14 0 Q5W0B1 Q5W0B1 RNF219 RING finger protein 219 1 0 T(0.009)S(0.051)S(0.94)EASMDAAYLDK 172.09 0.00019802 15310000 4272.9 3790.7 4079 3492.4 4147.6 3401.4 2080.7 677.97 4332.3 3102.8 TRUE FALSE FALSE 3934.695456 4118.351217 4230.171328 3477.949374 4098.142579 2695.911298 2139.078842 884.679932 3857.057529 3210.622069 1.225524329 1.282726876 1.317555052 1.083263399 1.27643257 0.839685033 0.666250588 0.275547826 1.201342745 1 11.64863714 -4.610898969 1.442185362 1.146633102 0.207167246 0.873914586 0.113105085 0.203734399 0.588891811 0.01985013 0.227718179 2.45E-05 4.610898969 -0.939465857 down GGDAKS(ph)PVLQEK ddPTM_HeLa_Curcumin_4h_R1 1 GGDAKSPVLQEK 12 1 A6NFI3 A6NFI3 ZNF316 Zinc finger protein 316 1 0 GGDAKS(1)PVLQEK 67.648 0.017573 63321000 7533.2 6417.7 6465.7 7300 7225.3 8019.9 5731.9 3841.9 8867.8 6840.5 TRUE FALSE FALSE 6936.939271 6972.417391 6705.32453 7269.794534 7139.143016 6356.482337 5892.721687 5013.277624 7895.024526 7078.206866 0.980041895 0.985054199 0.947319661 1.02706726 1.008608981 0.898035683 0.832516172 0.708269442 1.115398953 1 12.78916821 -4.589776942 1.384903691 0.990581468 0.677804528 0.81653341 0.046193271 0.122564516 0.311689949 0.00355291 0.044960868 2.57E-05 4.589776942 -0.31277694 GGDDYS(ph)EDEGDSSVSR ddPTM_HeLa_Curcumin_4h_R1 4 GGDDYSEDEGDSSVSR 16 0 A6NDA1;Q99871-3;Q99871;Q99871-2 A6NDA1 HAUS7 HAUS augmin-like complex subunit 7 1 0 GGDDYS(1)EDEGDSSVSR;GGDDYS(1)EDEGDSSVSR;GGDDYS(1)EDEGDSSVSR;GGDDYS(0.81)EDEGDS(0.051)S(0.139)VSR ;;; 287.43 2.07E-79 54165600 8132.7 6451.3 6811.5 6575.4 6609.2 7972.6 4948.68 4357.82 7213 6661.1 TRUE FALSE FALSE 7488.988213 7008.921626 7063.940182 6548.192737 6530.389607 6318.99289 5087.526642 5686.499257 6421.751946 6892.572729 1.086530169 1.016880329 1.024862625 0.950036074 0.94745313 0.916782911 0.738117223 0.82501839 0.931691576 1 12.75082687 -5.229145967 0.849564492 1.039613202 0.756444274 0.701447262 0.052632067 0.257965958 0.282366973 0.007601265 0.050077462 5.90E-06 5.229145967 -0.283168928 GGDGYDGGYGGFDDYGGYNNYGYGNDGFDDR ddPTM_HeLa_Curcumin_4h_R1 2 GGDGYDGGYGGFDDYGGYNNYGYGNDGFDDR 31 0 P31942;P31942-3;P31942-4;P31942-5 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 0 ; ; 137.42 2.80E-12 15474300 4000.3 3360.8 3453.3 3275.1 3056.2 4441.9 3887.5 3132.9 3393.8 3587.4 FALSE FALSE TRUE 3683.672034 3651.292577 3581.282336 3261.548504 3019.756811 3520.599869 3996.572787 4088.106788 3021.508631 3712.061883 0.992352 0.983629231 0.964769028 0.878635272 0.81349851 0.948421654 1.076644979 1.101303512 0.813970436 1 11.85800505 -4.705977449 5.976571672 0.969122872 1.092597546 0.317905132 0.076710221 0.174250907 12.8151263 0.009657945 0.036744605 1.97E-05 4.705977449 0.123474675 RPS(ph)QNAISFFNVGHSK ddPTM_HeLa_Curcumin_4h_R1 2 RPSQNAISFFNVGHSK 16 1 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 0 RPS(0.999)QNAIS(0.001)FFNVGHSK;RPS(0.998)QNAIS(0.002)FFNVGHSK ; 73.675 0.0094396 42896000 2351.35 1914.81 1767.01 2003.56 1953.89 2540.3 2246.01 3786.1 2162.92 2132.06 TRUE FALSE FALSE 2165.238166 2080.317644 1832.496945 1995.2698 1930.591138 2013.413145 2309.026996 4940.464461 1925.653087 2206.148926 0.98145603 0.942963378 0.830631569 0.904413014 0.875095564 0.912637003 1.046632423 2.239406598 0.872857251 1 11.10731447 -4.26116705 4.407827125 0.957842252 2.329910433 0.976126027 0.061463695 0.023435018 1.105765333 0.009422678 0.099969202 5.48E-05 4.26116705 1.372068181 up GGDQQSGYGK(ac)VSR ddPTM_HeLa_Curcumin_4h_R1 2 GGDQQSGYGKVSR 13 1 Q14103-3;H0YA96;Q14103-4 Q14103-3;Q14103-4 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 1 ; GGDQQSGYGK(1)VSR;GGDQQSGYGK(1)VSR 193.49 2.41E-13 3466800 901.89 942.32 944.8 792.65 833.93 1204.39 533.48 267.01 907.57 618.77 FALSE TRUE FALSE 830.5044548 1023.769942 979.8151191 789.3702243 823.9859294 954.5859377 548.448013 348.4201198 808.0118416 640.2722114 1.29711151 1.598960448 1.530310236 1.2328666 1.286930644 1.4909064 0.856585688 0.544174983 1.261981743 1 9.322541586 -4.552791781 4.928353997 1.239210636 0.605890823 0.639200225 0.186289177 0.105873263 6.393363105 0.0325072 0.141590454 2.80E-05 4.552791781 -0.633319814 GGDSIGET(ph)PT(ph)PGASK ddPTM_HeLa_Curcumin_4h_R1 2 GGDSIGETPTPGASK 15 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 2 0 GGDS(0.001)IGET(0.998)PT(0.866)PGAS(0.135)K;GGDSIGET(1)PT(0.982)PGAS(0.018)K ; 140.27 0.001941 75012000 16324.2 15315.9 16006.7 16133 16782.5 24463 18527.1 6862.3 17213.8 16347.5 TRUE FALSE FALSE 15032.12234 16639.73815 16599.92238 16066.24592 16582.37965 19389.09805 19046.92056 8954.58368 15325.48921 16915.57441 0.888655743 0.983693355 0.981339562 0.949790148 0.980302486 1.146227588 1.125999041 0.529369176 0.905998746 1 14.04606455 -4.506508731 0.003173477 1.892736089 0.000125316 0.00656422 0.159983595 613936.7104 334.1178861 97565.91101 101729.3613 3.12E-05 4.506508731 -1.892610773 GGDSIGET(ph)PTPGASKR ddPTM_HeLa_Curcumin_4h_R1 1 GGDSIGETPTPGASKR 16 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 GGDS(0.007)IGET(0.796)PT(0.197)PGASKR 88.781 0.0034565 24087000 3532.2 3379.8 3851.6 3899.9 3762.1 5481.9 3846.4 1817.6 3966.1 3208.1 TRUE FALSE FALSE 3252.622643 3671.934852 3994.343684 3883.763247 3717.239415 4344.892146 3954.319632 2371.777873 3531.028753 3319.581236 0.979829205 1.106143995 1.20326734 1.169955778 1.11979167 1.308867546 1.191210382 0.714481046 1.063697045 1 11.69678554 -7.192664907 4.595094354 0.99039641 1.133666203 0.076492222 0.148962694 0.286687674 11.8570384 0.023644313 0.028913959 6.42E-08 7.192664907 0.143269794 GGDSIGETPT(ph)PGASKR ddPTM_HeLa_Curcumin_4h_R1 1 GGDSIGETPTPGASKR 16 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 GGDS(0.001)IGET(0.196)PT(0.803)PGASKR 112.44 0.00075548 12857000 2528.6 2392.8 2943 2872.3 2435.4 3858.7 3147.5 1671 2963.1 3026.3 TRUE FALSE FALSE 2328.458642 2599.62297 3052.070169 2860.415184 2406.359446 3058.362123 3235.810379 2180.480208 2638.055343 3131.4637 0.74356878 0.830162256 0.974646511 0.913443507 0.768445582 0.97665578 1.033322015 0.696313423 0.84243523 1 11.61262144 GGDSIGETPTPGASK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GGDSIGETPTPGASKR 16 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 0 1 ; GGDSIGETPTPGASK(1)R;GGDSIGETPTPGASK(1)R 284.92 3.71E-94 7814300 1818.94 1947.74 1653.72 1850.86 2098.59 2475.6 1896.52 1486.2 2081.2 1492.49 FALSE TRUE FALSE 1674.96898 2116.093967 1715.008318 1843.201632 2073.565685 1962.132654 1949.731247 1939.335538 1852.897567 1544.353916 1.084575862 1.3702131 1.110502133 1.193509863 1.342675188 1.270520075 1.262489917 1.255758488 1.199788175 1 10.59278769 -7.437739845 5.065952236 1.036228467 1.253572193 0.388984213 0.08629634 0.096649219 4.081476947 0.012408509 0.014002959 3.65E-08 7.437739845 0.217343726 GGDVS(ph)PSPYSSSSWR ddPTM_HeLa_Curcumin_4h_R1 2 GGDVSPSPYSSSSWR 15 0 Q14004-2;Q14004;A0A2R8Y7W5;A0A2R8Y4Z0;A0A2R8YFE7 Q14004-2 CDK13 Cyclin-dependent kinase 13 1 0 GGDVS(0.863)PS(0.136)PYSSSSWR;GGDVS(0.994)PS(0.006)PYSSSSWR ; 194.77 1.55E-06 304852000 8458.4 6566.6 7871.7 7963 7566.9 9491.7 6788.5 5446.7 8491.9 6654.6 TRUE FALSE FALSE 7788.908715 7134.187644 8163.432127 7930.051216 7476.66966 7523.014426 6978.96704 7107.373756 7560.359816 6885.846855 1.131147538 1.036065395 1.185537857 1.151645017 1.08580249 1.092532928 1.013523418 1.032171337 1.097956428 1 12.74941838 -4.759422181 24.99366548 1.079901028 1.022847362 0.187247978 0.05285125 90.14394693 1116815.293 0.009278058 0.031537581 1.74E-05 4.759422181 -0.057053666 GGEFDEFVNDDT(ph)DDDLPISK ddPTM_HeLa_Curcumin_4h_R1 2 GGEFDEFVNDDTDDDLPISK 20 0 Q6PD62 Q6PD62 CTR9 RNA polymerase-associated protein CTR9 homolog 1 0 GGEFDEFVNDDT(0.999)DDDLPIS(0.001)K;GGEFDEFVNDDT(0.998)DDDLPIS(0.002)K ; 121.38 0.00010152 47658800 6987.1 5809.4 6685.9 6923.1 6638 7830.1 5864.1 5102.2 6774.3 5805.9 TRUE FALSE FALSE 6434.063662 6311.53865 6933.685336 6894.454047 6558.846185 6206.048997 6028.630864 6657.837292 6031.176238 6007.654593 1.070977627 1.050582811 1.154141808 1.147611591 1.091748216 1.033023604 1.003491591 1.108225713 1.003915279 1 12.55258615 -8.746533242 0.746795385 1.001902324 1.082757993 0.34210065 0.044678651 0.648547203 0.704587842 0.027980578 0.01063623 1.79E-09 8.746533242 0.08085567 GGEIQPVSVK ddPTM_HeLa_Curcumin_4h_R1 2 GGEIQPVSVK 10 0 P61604;B8ZZL8;B8ZZ54 P61604 HSPE1 "10 kDa heat shock protein, mitochondrial" 0 0 ; ; 148.32 8.25E-06 18422000 8269.7 6755.4 8097.7 7777 8569.3 12600.5 8573.6 8959.5 7813.4 7239.6 FALSE FALSE TRUE 7615.144519 7339.306675 8397.807885 7744.820835 8467.116694 9987.014263 8814.152141 11691.21031 6956.289568 7491.175561 1.016548665 0.979726962 1.121026709 1.033859208 1.130278769 1.333170499 1.176604669 1.560664306 0.928597856 1 12.87097642 -1 0.393265604 0.999504479 9.107280906 0.835081292 0.073897542 15.16275073 0.180850406 0.015640092 95.81670746 0.1 1 8.107776427 GGEIQPVSVK(ac)VGDK ddPTM_HeLa_Curcumin_4h_R1 2 GGEIQPVSVKVGDK 14 1 P61604;B8ZZL8;B8ZZ54 P61604 HSPE1 "10 kDa heat shock protein, mitochondrial" 0 1 ; GGEIQPVSVK(1)VGDK;GGEIQPVSVK(1)VGDK 221.86 2.38E-27 6895100 3245.1 2981.8 3296.4 3466.2 3449.7 5831.6 4279.8 3821.8 3425.5 2505 FALSE TRUE FALSE 2988.246911 3239.533505 3418.567484 3451.857783 3408.564581 4622.060424 4399.87967 4987.049227 3049.73122 2592.048564 1.152851437 1.249796609 1.318867066 1.331710305 1.315007993 1.783168915 1.697452637 1.923979858 1.176571791 1 11.33987703 -1.103964785 0.218592644 0.972996 6.061451603 0.891639178 0.094356963 7.483601908 0.092987631 0.05809429 13.40636229 0.078710961 1.103964785 5.088455603 GGELVYTDSEAR ddPTM_HeLa_Curcumin_4h_R1 2 GGELVYTDSEAR 12 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 208.6 1.27E-20 6857700 3919.5 3450.1 4307.3 3952.2 5265.4 4422.6 3942.5 3551.3 4085 3412.1 FALSE FALSE TRUE 3609.267439 3748.311271 4466.932327 3935.846844 5202.613544 3505.302907 4053.115939 4634.075022 3636.88572 3530.670221 1.022261274 1.061642984 1.26517971 1.114759124 1.473548425 0.992815156 1.147973525 1.312519927 1.030083665 1 11.78572636 -6.897907787 4.560207214 1.011819782 1.210967634 0.375718247 0.120007088 0.159318008 5.78756515 0.018231064 0.024172359 1.27E-07 6.897907787 0.199147852 GGET(ph)PEGLATSVVHYGAGAK ddPTM_HeLa_Curcumin_4h_R1 1 GGETPEGLATSVVHYGAGAK 20 0 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 0 GGET(0.994)PEGLAT(0.003)S(0.003)VVHYGAGAK 110.16 0.00023365 11180000 4238.1 3407.7 2918 2982.4 4364.1 7902.1 4393.5 1464.3 5169.6 3404.3 TRUE FALSE FALSE 3902.649913 3702.246404 3026.143647 2970.059619 4312.060958 6263.115385 4516.769785 1910.758329 4602.507814 3522.599172 1.107889295 1.050998488 0.859065565 0.843144359 1.224113431 1.77798128 1.282226437 0.542428541 1.306565859 1 11.78242461 -5.60021255 10.37646987 1.02337463 1.257485682 0.067450413 0.305118461 0.634688051 80.77177351 0.041709386 0.083462383 2.51E-06 5.60021255 0.234111053 DSAIPVES(ph)DT(ph)DDEGAPR ddPTM_HeLa_Curcumin_4h_R1 2 DSAIPVESDTDDEGAPR 17 0 C9JA08;Q96D46 C9JA08 NMD3 60S ribosomal export protein NMD3 2 0 DSAIPVES(1)DT(1)DDEGAPR;DSAIPVES(1)DT(1)DDEGAPR ; 160.03 0.00066439 59320000 7212 6309.1 6735.2 6805.5 6658.2 8398 7884.3 12307.9 7382.8 7517.3 TRUE FALSE FALSE 6641.16259 6854.430491 6984.812437 6777.340644 6578.805314 6656.160135 8105.512238 16060.52205 6572.925311 7778.525615 0.85378167 0.881199193 0.897960974 0.871288594 0.845765077 0.85570974 1.042037095 2.064725739 0.845009149 1 12.92528101 -4.26114312 3.580592022 0.909784349 2.198796477 0.980014625 0.050261438 0.03511923 0.798645235 0.009152055 0.121136847 5.48E-05 4.26114312 1.289012128 up GGFDGEYQDDSLDLLR ddPTM_HeLa_Curcumin_4h_R1 1 GGFDGEYQDDSLDLLR 16 0 Q5F1R6;Q5F1R6-3;Q5F1R6-2 Q5F1R6 DNAJC21 DnaJ homolog subfamily C member 21 0 0 148.85 0.0030272 5374200 918.36 789.52 958.05 973.07 1150.4 1335.2 999.71 1025.1 923.86 845.23 FALSE FALSE TRUE 845.670837 857.7625908 993.5561758 969.0436942 1136.682231 1058.264469 1027.759172 1337.648271 822.5148694 874.6016796 0.966921122 0.980746562 1.136009911 1.107982887 1.299657041 1.209995926 1.175116851 1.529437117 0.940445106 1 9.772482309 -1 0.279031022 0.964414839 4.716910216 0.794893417 0.078282285 15.51285274 0.197615363 0.034474535 28.72857169 0.1 1 3.752495378 S(ph)LTNSHLEK ddPTM_HeLa_Curcumin_4h_R1 2 SLTNSHLEK 9 0 F8VX12;F8VX04;Q9H2H9 F8VX12 SLC38A1 Sodium-coupled neutral amino acid transporter 1 1 0 S(0.897)LT(0.024)NS(0.079)HLEK;S(0.866)LT(0.107)NS(0.027)HLEK ; 90.793 0.0087544 27767000 8781.5 7395.1 8338.1 10896.6 7217.5 11472.1 4288.2 1637.37 12150.7 8122.3 TRUE FALSE FALSE 8086.435009 8034.299492 8647.117321 10851.51276 7131.436026 9092.657143 4408.515351 2136.596575 10817.79861 8404.54932 0.962149748 0.955946498 1.028861512 1.29114749 0.848520932 1.081873257 0.524539173 0.254219054 1.287136073 1 13.03695474 -4.610012683 3.420109469 1.001365604 0.292726734 0.775370712 0.144123605 0.061349628 1.355162119 0.014985181 0.07301687 2.45E-05 4.610012683 -0.708638871 down GGGDVLEPVS(ph)SDSLSTK ddPTM_HeLa_Curcumin_4h_R1 1 GGGDVLEPVSSDSLSTK 17 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 GGGDVLEPVS(0.743)S(0.191)DS(0.049)LS(0.013)T(0.003)K 107.98 0.001311 3612000 1341.4 1137.8 1299.8 1532 1315.7 1759.2 714.03 658.96 1385.8 1103.4 TRUE FALSE FALSE 1235.226775 1236.146362 1347.971731 1525.66099 1300.011137 1394.32209 734.0637601 859.8738705 1233.781207 1141.743068 1.081878059 1.082683484 1.180626158 1.336255969 1.138619689 1.221222295 0.642932531 0.753123794 1.080611954 1 10.15702232 -4.754702145 24.99610792 1.090896666 0.69802801 0.741841874 0.10104593 73.01155334 270875.7378 0.016601793 0.059397832 1.76E-05 4.754702145 -0.392868657 GGGDVLEPVSSDSLS(ph)TK ddPTM_HeLa_Curcumin_4h_R1 1 GGGDVLEPVSSDSLSTK 17 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 GGGDVLEPVS(0.001)SDS(0.01)LS(0.92)T(0.069)K 112.57 0.0019928 0 1446.1 1424.2 1377.5 1532.7 1860.5 1990.5 1637.6 1786.7 1419.7 1527.7 TRUE FALSE FALSE 1331.639659 1547.301502 1428.551362 1526.358094 1838.314753 1577.647862 1683.546649 2331.456605 1263.962462 1580.787461 0.842390069 0.978816912 0.903696036 0.965568194 1.162910763 0.998013902 1.065005062 1.474870381 0.799577738 1 10.62642769 -1.000000002 0.675989183 0.93413531 55.18643884 0.758305674 0.089111239 85.91943437 0.466823544 0.014900729 7026.303718 0.1 1.000000002 54.25230353 GGGESLQEAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 GGGESLQEASPR 12 0 P98175-5 P98175-5 RBM10 RNA-binding protein 10 1 0 GGGESLQEAS(1)PR;GGGESLQEAS(1)PR ; 154.23 0.00037227 59705000 6527.4 6442.9 5945 6885.1 5957.9 8290.7 6815 4778.5 7511.1 6444.4 TRUE FALSE FALSE 6010.749402 6999.795567 6165.32693 6856.611281 5886.855934 6571.115365 7006.210558 6235.442652 6687.151122 6668.34242 0.901385835 1.049705478 0.924566638 1.028233232 0.882806485 0.985419607 1.050667485 0.935081353 1.002820596 1 12.70311247 -5.011826893 24.86088384 0.958363185 0.999166702 0 0.058130909 1037.317273 2180523.104 0.008023978 0.021802927 9.73E-06 5.011826893 0.040803517 GGGGGGQGAEGPPGT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 GGGGGGQGAEGPPGTPR 17 0 Q8TER5;Q8TER5-4;Q8TER5-3;G3V485;G3V3N2;G3V5C1 Q8TER5 ARHGEF40 Rho guanine nucleotide exchange factor 40 1 0 GGGGGGQGAEGPPGT(1)PR 127.2 0.00099559 11529000 2356.8 4219.6 2782.1 3143.6 2127.1 2263 2093.1 1096 4045.9 4805.4 TRUE FALSE FALSE 2170.256793 4584.323422 2885.207073 3130.592616 2101.735722 1793.628291 2151.826753 1430.165355 3602.074892 4972.387292 0.436461737 0.921956226 0.580245846 0.62959549 0.42268142 0.360717737 0.432755259 0.287621472 0.724415594 1 12.27972295 -13.52287875 0.158327206 2.874755509 0.333559302 0.474410135 0.164882464 33.31068336 0.353228032 19.57617597 0.324453155 3.00E-14 13.52287875 -2.541196206 GGGGGQDNGLEGLGNDS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 GGGGGQDNGLEGLGNDSR 18 0 P08621;P08621-2;P08621-4 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 1 0 GGGGGQDNGLEGLGNDS(1)R;GGGGGQDNGLEGLGNDS(1)R ; 225.83 1.90E-23 137704000 5260.5 5385.6 5376.7 4608.8 5988.8 5921.1 7755 4761 4462.1 5276.3 TRUE FALSE FALSE 4844.125874 5851.107266 5575.965232 4589.730007 5917.387471 4692.997115 7972.584428 6212.606983 3972.618794 5459.651032 0.887259249 1.071699864 1.021304329 0.840663621 1.083839871 0.85957822 1.460273629 1.137912835 0.727632365 1 12.41459303 -4.767949368 24.99999968 0.957489848 1.299093254 0.552027576 0.129556142 59.44270833 228278.9893 0.013717357 0.042612426 1.71E-05 4.767949368 0.341603406 GGGGNFGPGPGS(ph)NFR ddPTM_HeLa_Curcumin_4h_R1 1 GGGGNFGPGPGSNFR 15 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 0 GGGGNFGPGPGS(1)NFR 153.14 0.0004082 10994000 1291.2 1226.3 1379 1260.6 1142.3 1663.2 1458.1 947.97 1510.1 1254.5 TRUE FALSE FALSE 1189.000158 1332.295908 1430.106953 1255.383971 1128.678819 1318.233572 1499.010362 1237.001689 1344.445808 1298.093782 0.915958596 1.026347962 1.101697715 0.967098055 0.869489427 1.015514896 1.15477817 0.952937073 1.035707764 1 10.3421789 -7.236661871 24.21473217 0.960313777 1.014314163 0.000568199 0.079818308 1002.781519 980005.8016 0.01345647 0.016475893 5.80E-08 7.236661871 0.054000386 GGGGNFGPGPGSNFR ddPTM_HeLa_Curcumin_4h_R1 3 GGGGNFGPGPGSNFR 15 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 ;; ;; 290.28 5.73E-112 56876000 4427.2 3656.63 3653.72 4056.9 3808.5 5324.6 4079.3 4174.63 4771.5 4331.1 FALSE FALSE TRUE 4076.782448 3972.692804 3789.130077 4040.113623 3763.086125 4220.217939 4193.754179 5447.455469 4248.078388 4481.605403 0.909670103 0.88644413 0.845484985 0.901488029 0.839673685 0.941675485 0.935770511 1.215514303 0.947892107 1 12.12979991 -4.26117257 6.46802987 0.930475848 1.221348653 0.769347191 0.048931525 0.057096306 14.10485609 0.008613039 0.072270487 5.48E-05 4.26117257 0.290872805 GGGGRS(ph)KSGS(ph)Y(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 GGGGRSKSGSYR 12 2 O14917-2;O14917 O14917-2 PCDH17 Protocadherin-17 3 0 GGGGRS(0.501)KS(0.501)GS(0.998)Y(1)R 69.229 0.020244 53105000 408.91 359.32 384.26 379.65 229.01 393.94 309.05 382.27 517.78 302.67 TRUE FALSE FALSE 376.544342 390.3780197 398.5010136 378.0791089 226.2792053 312.2324034 317.7211112 498.8223632 460.9808294 313.18776 1.202295843 1.2464664 1.272402899 1.207196312 0.722503349 0.996949572 1.014474867 1.59272624 1.471899251 1 8.29088402 GGGPVTLQDYRLPDS(ph)DDDEDEETAIQR ddPTM_HeLa_Curcumin_4h_R1 4 GGGPVTLQDYRLPDSDDDEDEETAIQR 27 1 Q96K21-3 Q96K21-3 ZFYVE19 Abscission/NoCut checkpoint regulator 1 0 GGGPVTLQDY(0.034)RLPDS(0.966)DDDEDEETAIQR;GGGPVTLQDYRLPDS(0.998)DDDEDEET(0.002)AIQR;GGGPVTLQDY(0.001)RLPDS(0.999)DDDEDEETAIQR;GGGPVT(0.039)LQDY(0.118)RLPDS(0.842)DDDEDEET(0.002)AIQR ;;; 123.31 4.61E-09 115114000 2824.2 2288.84 2250.2 2558.74 2171.78 3277.4 2336.52 2218.87 3313.89 2885.67 TRUE FALSE FALSE 2600.66159 2486.677131 2333.594391 2548.152612 2145.882942 2597.630296 2402.076463 2895.393249 2950.364558 2985.946818 0.87096715 0.83279351 0.781525772 0.853381781 0.718660804 0.869951963 0.804460565 0.969673415 0.988083425 1 11.54397275 -8.526039192 0.681400637 0.995595711 0.8278351 0.504715997 0.061937461 0.390639008 0.372641592 0.032071815 0.014067026 2.98E-09 8.526039192 -0.167760611 GGGQIIPTAR ddPTM_HeLa_Curcumin_4h_R1 2 GGGQIIPTAR 10 0 P13639;K7EJ74;Q15029-3;Q15029;Q15029-2;K7EP67 P13639;Q15029-3 EEF2;EFTUD2 Elongation factor 2;116 kDa U5 small nuclear ribonucleoprotein component 0 0 ; ; 130.66 0.0013653 29552000 7367.6 5661.5 5857.5 6234.6 6049.6 6774.7 5685 5874 6238.1 5992.2 FALSE FALSE TRUE 6784.446686 6150.854833 6074.584103 6208.802877 5977.462471 5369.550853 5844.5058 7664.955559 5553.796037 6200.428504 1.094189971 0.992004799 0.979703919 1.001350612 0.964040222 0.865996737 0.94259708 1.236197717 0.895711649 1 12.59815221 -7.106069701 10.72634729 1.044468764 0.988141685 0 0.102922586 1.047782157 100.1693016 0.015320576 0.018769431 7.83E-08 7.106069701 -0.056327079 GGGS(ph)CSGSAGGGGSGSLPSQR ddPTM_HeLa_Curcumin_4h_R1 1 GGGSCSGSAGGGGSGSLPSQR 21 0 O15234 O15234 CASC3 Protein CASC3 1 0 GGGS(0.997)CS(0.002)GSAGGGGSGSLPSQR 265.42 2.38E-105 0 484.01 483.3 358.54 415.66 421.03 634.89 390.2 243.01 294.95 426.29 TRUE FALSE FALSE 445.7000978 525.0742985 371.8278078 413.9401091 416.0094922 503.2066573 401.1479618 317.1026303 262.5947229 441.1035458 1.010420574 1.190365173 0.842949034 0.938419364 0.943110742 1.140790325 0.909419037 0.718884791 0.595313108 1 8.784973547 -4.371613286 3.515645444 1.005286956 0.712618807 0.109438066 0.160264058 0.160038349 3.164947969 0.012247721 0.100405339 4.25E-05 4.371613286 -0.292668148 GGGS(ph)GGGEES(ph)EGEEVDED ddPTM_HeLa_Curcumin_4h_R1 2 GGGSGGGEESEGEEVDED 18 0 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 2 0 GGGS(1)GGGEES(1)EGEEVDED;GGGS(1)GGGEES(1)EGEEVDED ; 92.38 0.0021801 3127200 1667.41 1298.49 1200.3 1412.56 1342.23 1653.46 1454.46 1728.19 1204.11 1171.45 TRUE FALSE FALSE 1535.432739 1410.72569 1244.784174 1406.715201 1326.224784 1310.513758 1495.268233 2255.107175 1072.022146 1212.1578 1.266693774 1.163813564 1.026915946 1.160505011 1.094102421 1.081141216 1.233559057 1.860407263 0.884391574 1 10.24336181 -4.262959374 3.165212688 1.122195675 1.968729419 0.830581805 0.103661405 0.103303674 1.591955624 0.014153217 0.215324446 5.46E-05 4.262959374 0.846533744 GGGSCSGSAGGGGSGS(ph)LPSQR ddPTM_HeLa_Curcumin_4h_R1 3 GGGSCSGSAGGGGSGSLPSQR 21 0 O15234 O15234 CASC3 Protein CASC3 1 0 GGGSCSGSAGGGGS(0.017)GS(0.983)LPSQR;GGGSCSGSAGGGGS(0.003)GS(0.992)LPS(0.005)QR;GGGSCSGSAGGGGS(0.3)GS(0.699)LPS(0.001)QR ;; 216.65 3.84E-23 14306600 435.619 426.51 417.59 372.178 496.3 657.42 558.4 54.343 493.85 374.191 TRUE FALSE FALSE 401.1392965 463.3756239 433.0662527 370.6380261 490.3819466 521.0636813 574.0672011 70.91193054 439.6758906 387.1941094 1.03601601 1.196752772 1.118473247 0.95724087 1.266501568 1.345742791 1.482634129 0.183143103 1.135543852 1 8.596913194 -7.476181479 11.81805776 1.015866726 1.109116353 0 0.335128708 5.093017353 1284.367119 0.053079848 0.060039727 3.34E-08 7.476181479 0.093249626 GGGSGGGEES(ph)EGEEVDED ddPTM_HeLa_Curcumin_4h_R1 2 GGGSGGGEESEGEEVDED 18 0 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 0 GGGSGGGEES(1)EGEEVDED;GGGSGGGEES(1)EGEEVDED ; 214.48 6.88E-17 40116000 12314.2 9748 9678.9 10549.7 10961 14217.8 11671.1 13503.9 11929.6 9835.5 TRUE FALSE FALSE 11339.51808 10590.57368 10037.60855 10506.04814 10830.29723 11268.86801 11998.55965 17621.17695 10620.95273 10177.28289 1.114198966 1.040609148 0.986275871 1.032303833 1.064163918 1.107257028 1.178955108 1.731422535 1.043594134 1 13.31306483 -4.025803191 1.62641605 1.048907171 2.359322065 0.967834726 0.037266378 0.307175062 0.476147271 0.007110422 0.758145066 9.42E-05 4.025803191 1.310414895 GGGSGNPTTTIES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 GGGSGNPTTTIESPK 15 0 G3V0E6;O00592-2;O00592 G3V0E6 PODXL Podocalyxin 1 0 GGGSGNPTT(0.001)T(0.003)IES(0.995)PK 176.17 8.52E-05 14097000 3180.5 2820.6 3152.3 3004.2 3530.3 3338.2 2663.9 1873.6 3530.7 2818.5 TRUE FALSE FALSE 2928.760069 3064.400096 3269.127011 2991.769416 3488.203478 2645.819691 2738.641864 2444.852015 3143.391043 2916.442665 1.004223434 1.050732158 1.120929635 1.025828298 1.196047335 0.907207854 0.939035043 0.838299358 1.077816849 1 11.509994 -5.043527417 24.99938894 1.02884037 0.897280501 0.532110603 0.067812682 310.3673507 178255.1101 0.009692256 0.024712276 9.05E-06 5.043527417 -0.131559869 GGGT(ph)PDANSLAPPGK ddPTM_HeLa_Curcumin_4h_R1 1 GGGTPDANSLAPPGK 15 0 Q9BRQ0;Q5T171 Q9BRQ0 PYGO2 Pygopus homolog 2 1 0 GGGT(0.93)PDANS(0.07)LAPPGK 174.59 0.00031206 72255000 6984.9 5084.9 5572.8 5539.4 5719.7 7556.6 5684.2 3181.2 6393.5 5366.4 TRUE FALSE FALSE 6432.037795 5524.416098 5779.33287 5516.479431 5651.496313 5989.27598 5843.683354 4151.133236 5692.149046 5552.882001 1.158324235 0.994873671 1.040780782 0.993444383 1.017759123 1.078588736 1.052369446 0.74756374 1.025080138 1 12.43902102 -4.261640486 6.59235901 1.058681336 0.741704978 0.745770739 0.050219747 0.053839517 14.67661618 0.009164117 0.075860479 5.47E-05 4.261640486 -0.316976358 GGGTPDANS(ph)LAPPGK ddPTM_HeLa_Curcumin_4h_R1 1 GGGTPDANSLAPPGK 15 0 Q9BRQ0;Q5T171 Q9BRQ0 PYGO2 Pygopus homolog 2 1 0 GGGT(0.211)PDANS(0.789)LAPPGK 107.45 0.0024985 169460000 9290.6 7215.8 8215.1 8607.4 9043.3 10579 8912.3 5032.9 10038 8100.9 TRUE FALSE FALSE 8555.239207 7839.501599 8519.558833 8571.784859 8935.464554 8384.79615 9162.355152 6567.408041 8936.856514 8382.405672 1.020618608 0.935232904 1.016362029 1.022592463 1.065978539 1.000285178 1.093046019 0.783475329 1.066144597 1 13.03314863 -4.248905111 24.97841413 1.013534624 0.783475184 0.734870821 0.042977151 712.3838784 1419621.109 0.00516495 0.122401869 5.64E-05 4.248905111 -0.230059439 GGGTSSGGSSTNS(ph)LTGSRPPK ddPTM_HeLa_Curcumin_4h_R1 1 GGGTSSGGSSTNSLTGSRPPK 21 1 Q5T9C2-3;Q5T9C2-2;Q5T9C2 Q5T9C2-3 FAM102A Protein FAM102A 1 0 GGGTSSGGSS(0.002)T(0.017)NS(0.907)LT(0.061)GS(0.012)RPPK 79.94 0.00052102 6379700 1261.9 1134.2 1305.8 1355.5 1099.2 1745.2 963.44 1314.5 1389.1 1324.7 TRUE FALSE FALSE 1162.019283 1232.235194 1354.194097 1349.8913 1086.092758 1383.225848 990.4715334 1715.284999 1236.719205 1370.733226 0.847735548 0.898960622 0.9879341 0.984795053 0.792344372 1.009113824 0.722585193 1.251363114 0.902231872 1 10.4207321 -4.237394382 24.4430473 0.918659792 1.251363644 0.558327259 0.091684237 3179.721953 3232295.457 0.012527731 1.022156733 5.79E-05 4.237394382 0.332703852 GGIDNPAIT(ph)SDQELDDK ddPTM_HeLa_Curcumin_4h_R1 1 GGIDNPAITSDQELDDK 17 0 Q13017-2;Q13017;H0YK04;A0A0A0MSK6 Q13017-2 ARHGAP5 Rho GTPase-activating protein 5 1 0 GGIDNPAIT(0.718)S(0.282)DQELDDK 199.33 8.03E-08 18281000 4694.6 3134.9 4221.3 3906.9 3852.4 3951.1 3359.5 2169.4 4369.4 3751.7 TRUE FALSE FALSE 4323.017456 3405.866787 4377.745091 3890.734283 3806.462646 3131.597322 3453.758528 2830.840073 3890.087752 3882.071296 1.113585281 0.877332364 1.127682816 1.002231537 0.980523632 0.806682073 0.88966901 0.729208677 1.002064995 1 11.9226109 -5.344603211 1.485767123 1.045002661 0.795719894 0.598896375 0.076348712 0.202005962 0.839169949 0.011519787 0.040157412 4.52E-06 5.344603211 -0.249282767 GGIDNPAITS(ph)DQELDDK ddPTM_HeLa_Curcumin_4h_R1 1 GGIDNPAITSDQELDDK 17 0 Q13017-2;Q13017;H0YK04;A0A0A0MSK6 Q13017-2 ARHGAP5 Rho GTPase-activating protein 5 1 0 GGIDNPAIT(0.207)S(0.793)DQELDDK 226.79 5.24E-22 18367000 5183.1 4295.2 4422.7 4568.1 4920.5 5338.1 4419.7 2298.3 4959.6 5062.9 TRUE FALSE FALSE 4772.852166 4666.457949 4586.609153 4549.198413 4861.826251 4230.917887 4543.704887 2999.04109 4415.544288 5238.835398 0.911052133 0.89074338 0.875501672 0.868360631 0.928035695 0.80760657 0.867312015 0.572463317 0.842848449 1 12.35503042 -3.005302419 0.383187801 0.959374285 1.57E-60 0.588256685 0.068430804 5.430982961 0.264007689 0.015826897 2.95214467 0.000987865 3.005302419 -0.959374285 GGIDNPAITS(ph)DQELDDKK ddPTM_HeLa_Curcumin_4h_R1 1 GGIDNPAITSDQELDDKK 18 1 Q13017-2;Q13017;H0YK04;A0A0A0MSK6 Q13017-2 ARHGAP5 Rho GTPase-activating protein 5 1 0 GGIDNPAIT(0.161)S(0.839)DQELDDKK 108.69 0.00038855 135780000 4405 4091 4395.1 4399.7 4299.7 4730.9 3590.7 2013.2 5154 4269.9 TRUE FALSE FALSE 4056.339602 4444.607811 4557.986272 4381.495207 4248.428886 3749.658012 3691.445378 2627.015412 4588.619095 4418.278707 0.918081423 1.005959131 1.03162036 0.991674699 0.961557468 0.848669416 0.835494006 0.594578927 1.038553563 1 12.10926871 -3.829163797 0.901673333 0.972062968 0.0710314 0.889520778 0.042725341 1.049803626 0.375452452 0.007091198 1.118694725 0.000148196 3.829163797 -0.901031568 GGIY(ph)S(ph)HT(ph)PVSLGR ddPTM_HeLa_Curcumin_4h_R1 1 GGIYSHTPVSLGR 13 0 F6SDV2;Q9GZM7-3;Q9GZM7 F6SDV2 TINAGL1 Tubulointerstitial nephritis antigen-like 3 0 GGIY(1)S(0.999)HT(0.566)PVS(0.435)LGR 72.705 0.018272 10838000 1132.2 1766.6 963.7 904.95 958.74 1144.9 876.41 681.2 1075.8 1101.4 TRUE FALSE FALSE 1042.585175 1919.297032 999.4155698 901.2055567 947.3076517 907.4348343 900.9997059 888.8947441 957.7874315 1139.673568 0.91481035 1.684076113 0.876931428 0.790757619 0.831209636 0.796223462 0.790576996 0.779955567 0.840405058 1 10.15440494 -6.534931037 24.99992968 1.025710008 0.802593332 0.283846736 0.219636063 285.2877512 591767.3202 0.034534843 0.048859444 2.92E-07 6.534931037 -0.223116676 GGK(ac)GLGK(ac)GGAK ddPTM_HeLa_Curcumin_4h_R1 2 GGKGLGKGGAK 11 2 P62805 P62805 HIST1H4A Histone H4 0 2 ; GGK(1)GLGK(1)GGAK;GGK(1)GLGK(1)GGAK 140.16 6.52E-05 250420000 10290.6 8919.6 10920.2 17365.9 10266.7 25241.1 17808.7 9178.5 13386 9871.1 FALSE TRUE FALSE 9476.088151 9690.570479 11324.91222 17294.04451 10144.27631 20005.81133 18308.36419 11976.9824 11917.58929 10214.11999 0.927743962 0.948742573 1.108750654 1.693150709 0.993162046 1.958642678 1.792456346 1.172590728 1.166775924 1 13.31827729 -6.4129523 4.19673616 0.965522161 1.530834514 0.44701723 0.272404611 0.13812353 4.1462111 0.039040408 0.06021607 3.86E-07 6.4129523 0.565312353 GGK(ac)GLGK(ac)GGAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GGKGLGKGGAKR 12 3 P62805 P62805 HIST1H4A Histone H4 0 3 ; GGK(1)GLGK(1)GGAK(1)R;GGK(1)GLGK(1)GGAK(1)R 205.18 8.77E-28 2067740000 11438.3 7443.7 10880.2 17589.8 9696.3 23769.7 15289.3 5842 15736.3 9583.2 FALSE TRUE FALSE 10532.94649 8087.10026 11283.42978 17517.01807 9580.677955 18839.59628 15718.27661 7623.198907 14010.06726 9916.215487 1.062194191 0.815543013 1.137876622 1.766502361 0.966162743 1.899877661 1.585108415 0.768760917 1.412844172 1 13.27557391 -6.508443664 23.9110622 1.012370082 1.415738244 0.15981755 0.347644407 367.2998028 608415.63 0.046136577 0.068830796 3.10E-07 6.508443664 0.403368162 GGK(ac)GLGK(ac)GGAKR ddPTM_HeLa_Curcumin_4h_R1 1 GGKGLGKGGAKR 12 3 P62805 P62805 HIST1H4A Histone H4 0 2 GGK(1)GLGK(0.999)GGAK(0.001)R 97.163 0.0033046 19245000 5389.5 3478.2 3593.8 6735.7 2889.3 11312 6078.9 3740.9 9542.4 5562.8 FALSE TRUE FALSE 4962.915388 3778.840109 3726.989389 6707.829458 2854.846985 8965.763687 6249.457573 4881.483189 8495.622594 5756.106886 0.862200005 0.656492345 0.647484396 1.165341365 0.495968376 1.557608965 1.085709091 0.848052909 1.475932043 1 12.49087767 -5.26337111 24.99983861 0.882399577 1.155982175 0.129363674 0.310352374 202.5705089 2621623.498 0.033905877 0.079623432 5.45E-06 5.26337111 0.273582597 GGKDPLSS(ph)PGGPGSR ddPTM_HeLa_Curcumin_4h_R1 2 GGKDPLSSPGGPGSR 15 1 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 0 GGKDPLS(0.295)S(0.705)PGGPGSR;GGKDPLS(0.014)S(0.986)PGGPGSR ; 172.26 0.0013455 19509400 6671.5 5659.5 6097.5 6014 6806.8 9022.9 7460.5 4040.8 6654.5 5606.8 TRUE FALSE FALSE 6143.443735 6148.681962 6323.478714 5989.115662 6725.633356 7151.448831 7669.821551 5272.821318 5924.517999 5801.635883 1.058915771 1.059818659 1.089947532 1.032314985 1.159264989 1.232660749 1.322010155 0.908850784 1.021180598 1 12.50224404 -5.732884615 5.385247494 1.036438082 1.174639654 0.219485712 0.100657775 0.168194652 12.91404604 0.01374916 0.027236399 1.85E-06 5.732884615 0.138201573 GGLASLAK ddPTM_HeLa_Curcumin_4h_R1 1 GGLASLAK 8 0 F8VWT8;F8VS45;Q92994-9;Q92994-3;Q92994-7;Q92994-8;Q92994-5;Q92994 F8VWT8 BRF1 Transcription factor IIIB 90 kDa subunit 0 0 105.39 0.0090622 4486500 3805.4 2958 3688.1 3890.1 4057.3 3637.1 3342.7 2516.3 3927.8 4159.9 FALSE FALSE TRUE 3504.198575 3213.676339 3824.78423 3874.003797 4008.919347 2882.724461 3436.487166 3283.508286 3496.930167 4304.456215 0.81408624 0.746592875 0.88856386 0.899998421 0.931341648 0.669707001 0.798355702 0.76281605 0.812397662 1 12.07161528 -13.52287875 0.210673699 1.948976196 0.783848682 0 0.095298902 33.06913041 0.411303617 12.87514513 0.069602262 3.00E-14 13.52287875 -1.165127514 GGLLTSEEDSGFST(ph)SPKDNSLPK ddPTM_HeLa_Curcumin_4h_R1 1 GGLLTSEEDSGFSTSPKDNSLPK 23 1 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 0 GGLLTSEEDSGFS(0.037)T(0.48)S(0.48)PKDNS(0.003)LPK 108.45 1.45E-05 102440000 3545.1 2388.5 2740.8 2891.4 2728.3 3682.1 2439.4 1425.5 3661.7 2509.7 TRUE FALSE FALSE 3264.501594 2594.951297 2842.376459 2879.436153 2695.766804 2918.390954 2507.842999 1860.128388 3260.020671 2596.911888 1.257070603 0.99924503 1.094521717 1.108792395 1.038066334 1.123792828 0.965701998 0.716284752 1.255345122 1 11.34258135 -4.296083945 1.877474397 1.10740046 0.607939871 0.663800854 0.085860093 0.403744832 1.533918604 0.014212077 0.342771706 5.06E-05 4.296083945 -0.499460589 GGLLTSEEDSGFSTS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 GGLLTSEEDSGFSTSPK 17 0 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 0 GGLLTSEEDSGFST(0.018)S(0.982)PK 210.07 3.98E-11 18996000 3958.1 2778.7 3728.4 3390.4 4811.8 4233.4 3771.2 2029.3 3498 2810.8 TRUE FALSE FALSE 3644.812208 3018.878446 3866.577784 3376.371423 4754.422428 3355.34512 3877.009722 2648.024228 3114.278152 2908.475091 1.253169477 1.037959189 1.329417534 1.160873419 1.634678751 1.153644097 1.333004272 0.91045106 1.070759781 1 11.50604723 -9.43607764 0.511553375 0.934833305 1.248034913 0.140842495 0.184299343 2.212211336 0.713812013 0.355248135 0.044429463 3.66E-10 9.43607764 0.313201608 GGLLTSEEDSGFSTS(ph)PKDNSLPK ddPTM_HeLa_Curcumin_4h_R1 1 GGLLTSEEDSGFSTSPKDNSLPK 23 1 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 1 0 GGLLTSEEDSGFS(0.008)T(0.298)S(0.693)PKDNSLPK 110.6 5.85E-06 91349000 3807.5 2203.7 2860.4 3354 2882.5 3881.8 3122.3 1480.1 4079.6 3182.8 TRUE FALSE FALSE 3506.132357 2394.178009 2966.40894 3340.122037 2848.12807 3076.670923 3209.903335 1931.375676 3632.078087 3293.402063 1.064592871 0.726961957 0.900712662 1.014185931 0.864798168 0.934192323 0.974646664 0.586437866 1.102834703 1 11.68536293 -2.740301716 0.35066357 1.015556114 1.19E-38 0.359851197 0.119919785 14.21425399 0.535303587 0.036139801 7.678402124 0.001818437 2.740301716 -1.015556114 GLIVYCVTS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 GLIVYCVTSPK 11 0 E9PCH4;Q8TEU7;Q8TEU7-4;A0A5F9ZHG7 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 0 GLIVYCVT(0.3)S(0.7)PK 100.02 0.01108 48245000 3363.5 2383.7 3202.4 3028.9 3088.8 3554.3 1691.3 775.01 3287.9 3201.6 TRUE FALSE FALSE 3097.275426 2589.736406 3321.083761 3016.367214 3051.968077 2817.098115 1738.753326 1011.306981 2927.225596 3312.855362 0.934926246 0.781723355 1.002483779 0.910503745 0.921250023 0.850353489 0.524850359 0.305267472 0.883595955 1 11.6938595 -4.609615521 1.618594076 0.95132745 0.245763432 0.908939501 0.064376687 0.106144257 0.414419249 0.009417552 0.095231044 2.46E-05 4.609615521 -0.705564019 down GGLS(ph)PANDTGAK ddPTM_HeLa_Curcumin_4h_R1 4 GGLSPANDTGAK 12 0 P30419;B7Z8J4;K7EN42 P30419 NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1 0 GGLS(1)PANDTGAK;GGLS(1)PANDTGAK;GGLS(1)PANDTGAK;GGLS(1)PANDTGAK ;;; 195.94 2.63E-06 4814272000 28930.1 24874.5 24588.8 25969.3 26166.2 27593.4 21546.8 20124.8 26992.3 22767.1 TRUE FALSE FALSE 26640.25206 27024.54094 25500.08256 25861.84592 25854.18515 21870.2178 22151.34522 26260.75888 24031.31222 23558.25503 1.130824504 1.147136785 1.082426628 1.097782747 1.097457563 0.928346254 0.940279541 1.11471579 1.020080315 1 14.52394506 -5.27849072 24.79086765 1.076088432 0.989030424 0.284643913 0.06308229 780.2974001 1134470.895 0.010241048 0.022954184 5.27E-06 5.27849072 -0.087058008 GGLS(ph)PANDTGAKK ddPTM_HeLa_Curcumin_4h_R1 1 GGLSPANDTGAKK 13 1 P30419;B7Z8J4;K7EN42 P30419 NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1 0 GGLS(0.997)PANDT(0.003)GAKK 127.32 0.00047476 0 1332.2 908.78 1034.2 1024.3 1081.8 975.43 925.55 762.83 1335.6 1082.9 TRUE FALSE FALSE 1226.754964 987.3308938 1072.528362 1020.061718 1068.900242 773.1148226 951.518442 995.4133554 1189.088022 1120.530694 1.094798179 0.881127932 0.957161073 0.910338042 0.953923214 0.689954168 0.849167673 0.888340998 1.061182909 1 10.12996645 -6.379797174 0.85190171 1.041543366 0.826621999 0.535496994 0.07441775 0.320622104 0.462275058 0.015315397 0.032080724 4.17E-07 6.379797174 -0.214921367 GGLSPANDTGAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 GGLSPANDTGAKK 13 1 P30419;B7Z8J4;K7EN42 P30419 NMT1 Glycylpeptide N-tetradecanoyltransferase 1 0 1 ; GGLSPANDTGAK(1)K;GGLSPANDTGAK(1)K 184.87 1.94E-09 8038000 6043.4 6587.8 5847.7 6127.8 6368.6 6623.2 6256.5 6381.3 6942.4 5956.9 FALSE TRUE FALSE 5565.058513 7157.220077 6064.420906 6102.444787 6292.658604 5249.473661 6432.040551 8326.928994 6180.836089 6163.901832 0.902846714 1.161150887 0.983860722 0.990029523 1.020888842 0.851647837 1.043501459 1.350918496 1.002747328 1 12.58962817 -4.292375691 3.634570466 0.971360109 1.381805754 0.652017947 0.077767399 0.108403214 2.584635513 0.010906864 0.114000683 5.10E-05 4.292375691 0.410445645 GGLTSPIFCSTK(ac)PK ddPTM_HeLa_Curcumin_4h_R1 2 GGLTSPIFCSTKPK 14 1 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 0 1 ; GGLTSPIFCSTK(1)PK;GGLTSPIFCSTK(1)PK 201.6 9.97E-15 2076800 820.1 697.73 517 767.79 743.72 653.93 622.72 312.98 705.67 385.99 FALSE TRUE FALSE 755.1882196 758.0386722 536.1604748 764.6130884 734.8516247 518.2975467 640.1918472 408.4061612 628.2597665 399.4031238 1.890791971 1.897928752 1.34240431 1.914389355 1.839874505 1.297680253 1.602871408 1.022541229 1.572996627 1 8.641701806 -9.459116697 1.207190819 1.001618861 1.638193261 0.014941871 0.33560534 0.380551326 0.996020081 0.199150439 0.049802607 3.47E-10 9.459116697 0.636574401 GGLVS(ph)DAYGEDDFSR ddPTM_HeLa_Curcumin_4h_R1 2 GGLVSDAYGEDDFSR 15 0 J3QQJ0;Q9UHR5-2;Q9UHR5;J3KS14;F5H478;J3KRU5;X6R3T8;J3QLH3 J3QQJ0 SAP30BP SAP30-binding protein 1 0 GGLVS(1)DAYGEDDFSR;GGLVS(1)DAYGEDDFSR ; 209.53 7.42E-10 38464000 3669.7 3389.3 3119.7 3941.9 3262.7 4443.4 3198.8 4415 3858.4 3754.6 TRUE FALSE FALSE 3379.239373 3682.25599 3235.318826 3925.589462 3223.794433 3521.788753 3288.549719 5761.113176 3435.143173 3885.072071 0.869800949 0.947796057 0.83275645 1.010428994 0.829790124 0.906492515 0.846457841 1.482884505 0.884190334 1 11.92372565 -4.256749228 24.99900895 0.92174745 1.482884732 0.879425787 0.064071982 129.9899422 692836.2069 0.009480677 0.102737212 5.54E-05 4.256749228 0.561137282 GGLWDDDDAPRPSQFEEDLALMEEMEAEHR ddPTM_HeLa_Curcumin_4h_R1 1 GGLWDDDDAPRPSQFEEDLALMEEMEAEHR 30 1 M0R2J2;A0A2R8Y7K6;M0QZR8;A0A087WYJ2;M0R2B7;P28340 M0R2J2 POLD1 DNA polymerase;DNA polymerase delta catalytic subunit 0 0 81.974 1.80E-06 5356700 956.86 697.83 949.23 997.28 695.22 869.24 752.75 707.75 1185.2 1090.4 FALSE FALSE TRUE 881.1235213 758.1473157 984.4092988 993.1535196 686.9299556 688.9498256 773.8701391 923.5397169 1055.186525 1128.291319 0.780936188 0.671942878 0.872477952 0.880227919 0.608823222 0.610613424 0.685877952 0.818529489 0.935207519 1 10.1399239 -9.872151911 0.254605359 1.216086842 0.686982017 0.486292759 0.093638291 4.37998041 0.294790367 0.723748555 0.076913274 1.34E-10 9.872151911 -0.529104826 GGNFGFGDSR ddPTM_HeLa_Curcumin_4h_R1 1 GGNFGFGDSR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 142.36 0.01159 56615000 2220.8 1940.9 2219.8 2455.7 2184.2 2557.8 2307.5 2056.7 2469 2087 FALSE FALSE TRUE 2045.021337 2108.662748 2302.067741 2445.538964 2158.154842 2027.283448 2372.24224 2683.778362 2198.156877 2159.523095 0.94697822 0.976448343 1.066007465 1.132443997 0.99936641 0.938764421 1.098502834 1.242764372 1.01788996 1 11.07649703 -6.752469668 5.979755339 0.974222217 1.073251675 0.256894808 0.077296261 0.166712287 21.19281796 0.012576428 0.017346964 1.77E-07 6.752469668 0.099029458 GGNGGGK(ac)PPSGPNR ddPTM_HeLa_Curcumin_4h_R1 1 GGNGGGKPPSGPNR 14 1 Q8N3U4;Q8N3U4-2;B1AMS9;B1AMT0;B1AMT1;B1AMT2;B1AMT3;B1AMT4 Q8N3U4 STAG2 Cohesin subunit SA-2 0 1 GGNGGGK(1)PPSGPNR 126.83 1.66E-06 0 150.83 137.33 65.182 54.731 0 164.44 89.368 0 0 0 FALSE TRUE FALSE 138.8916463 149.2001933 67.59770226 54.50453762 0 130.3332904 91.87542556 0 0 0 0 GGNIGDGGGAADR ddPTM_HeLa_Curcumin_4h_R1 2 GGNIGDGGGAADR 13 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 ; ; 155.88 0.00011839 15115600 10780 9108.9 9444.2 8605.4 10190.7 11987.7 9240.4 9181.2 11275.1 10182.8 FALSE FALSE TRUE 9926.751625 9896.232728 9794.21036 8569.793135 10069.18256 9501.315891 9499.660755 11980.50561 10038.24974 10536.65154 0.942116344 0.939219892 0.929537275 0.81333174 0.955634009 0.901739595 0.901582511 1.137031586 0.952698274 1 13.36312884 -8.751443117 0.788443446 0.997710521 0.933167963 0.016504932 0.077705629 1.129488159 1.37574069 0.039434848 0.015596124 1.77E-09 8.751443117 -0.064542558 GGNLPPVS(ph)PNDS(ph)GAK ddPTM_HeLa_Curcumin_4h_R1 2 GGNLPPVSPNDSGAK 15 0 Q9UK61-3;Q9UK61;Q9UK61-2;A0A087X0F1;Q9UK61-4 Q9UK61-3 FAM208A Protein FAM208A 2 0 GGNLPPVS(1)PNDS(1)GAK;GGNLPPVS(1)PNDS(1)GAK ; 111.34 0.0014438 0 4074.5 3714.7 3831.6 3921.5 3968.9 4396.6 4577.7 4307.2 4022.8 3438.6 TRUE FALSE FALSE 3751.999026 4035.782116 3973.602467 3905.273872 3921.57346 3484.6956 4706.137942 5620.445452 3581.508905 3558.091094 1.054497742 1.13425486 1.116779296 1.097575573 1.102156565 0.979372227 1.322658082 1.579623822 1.006581566 1 11.79688773 -4.511753382 2.869467717 1.048587221 1.573694538 0.899311352 0.055047059 0.065932639 0.983277966 0.008669655 0.060745841 3.08E-05 4.511753382 0.525107317 GGNLPPVS(ph)PNDSGAK ddPTM_HeLa_Curcumin_4h_R1 2 GGNLPPVSPNDSGAK 15 0 Q9UK61-3;Q9UK61;Q9UK61-2;A0A087X0F1;Q9UK61-4 Q9UK61-3 FAM208A Protein FAM208A 1 0 GGNLPPVS(1)PNDSGAK;GGNLPPVS(1)PNDSGAK ; 193.31 1.93E-06 57073900 14375.4 12253.4 12805.4 13530.4 12551.2 13378.3 11235.3 10070 14482.2 12145.6 TRUE FALSE FALSE 13237.57192 13312.5293 13279.97939 13474.41479 12401.53514 10603.48978 11550.53228 13140.29664 12893.53889 12567.6587 1.053304537 1.059268844 1.05667887 1.072149962 0.986781662 0.843712423 0.919067947 1.04556441 1.025930064 1 13.61742829 -5.519915102 23.9256682 1.033973089 0.931216362 0.480429752 0.050085394 45.57866935 367956.9369 0.007445016 0.015138144 3.02E-06 5.519915102 -0.102756727 GGNRFEPYANPTK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 GGNRFEPYANPTKR 14 2 A0A087X0X3;P52272-2;P52272;M0R2T0;M0QYQ7;M0R0N3;M0R019;M0R0Y6 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 1 GGNRFEPYANPTK(1)R 62.287 0.019612 3704500 366.06 344.96 265.84 267.18 480.61 807.89 517.17 511.3 1116.1 269.08 FALSE TRUE FALSE 337.0859647 374.7768053 275.6922643 266.07448 474.8790396 640.3245072 531.6803983 667.1930163 993.6666223 278.43051 1.21066461 1.346033541 0.990165425 0.955622572 1.705556764 2.299764158 1.909562276 2.396264031 3.568813714 1 8.121173498 -5.5538474 3.504397641 1.105082245 2.163794998 0 0.795960734 0.051256842 1.32257861 0.024364443 0.053322176 2.79E-06 5.5538474 1.058712753 GGNVFAALIQDQS(ph)EEEEEEEKHPPKPAKPEK ddPTM_HeLa_Curcumin_4h_R1 1 GGNVFAALIQDQSEEEEEEEKHPPKPAKPEK 31 3 Q5STZ8;Q8NE71;Q8NE71-2;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 0 GGNVFAALIQDQS(1)EEEEEEEKHPPKPAKPEK 46.847 0.0060137 288230000 5153.4 3297 3957.8 4867.8 4485.8 5542.5 4233.2 3305.1 5019.2 4797.9 TRUE FALSE FALSE 4745.502952 3581.977989 4104.47955 4847.658333 4432.309765 4392.923023 4351.972199 4312.809775 4468.606317 4964.626668 0.955863002 0.721499969 0.826744854 0.976439651 0.89277806 0.884844585 0.876596065 0.868707773 0.900089094 1 12.27746952 -7.492853997 18.51321748 0.980529434 0.867056977 0.251846359 0.065343648 12.74731476 7860.830354 0.010932135 0.011982716 3.21E-08 7.492853997 -0.113472458 T(ph)LSPTPASATAPTSQGIPTS(ph)DEESTPKK ddPTM_HeLa_Curcumin_4h_R1 1 TLSPTPASATAPTSQGIPTSDEESTPKK 28 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 2 0 T(0.51)LS(0.343)PT(0.135)PAS(0.007)AT(0.002)APT(0.001)S(0.001)QGIPT(0.155)S(0.842)DEES(0.001)T(0.001)PKK 92.405 2.10E-07 7539700 2321.1 2132.6 2699.3 2203.3 1896.2 2316.8 1272.7 644.7 2688.2 2367.5 TRUE FALSE FALSE 2137.382486 2316.932441 2799.338433 2194.183328 1873.589053 1836.269564 1308.408537 841.2660622 2393.311186 2449.770449 0.872482761 0.945775325 1.142694179 0.895668951 0.764801884 0.749568012 0.534094342 0.343406078 0.976953243 1 11.25843086 -4.608093281 0.874317851 0.952999087 0.177216316 0.880979878 0.07731938 0.391985713 0.305577153 0.013936473 0.257954467 2.47E-05 4.608093281 -0.77578277 down GGPASVPSS(ph)SPGTSVK ddPTM_HeLa_Curcumin_4h_R1 2 GGPASVPSSSPGTSVK 16 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 0 GGPASVPS(0.056)S(0.601)S(0.256)PGT(0.069)S(0.019)VK;GGPASVPS(0.031)S(0.803)S(0.16)PGT(0.005)S(0.001)VK ; 207.64 1.49E-10 73186000 13915.5 11920.3 12550.4 13265.2 13860.4 20876.2 16839.7 6320.5 13708.5 10293.4 TRUE FALSE FALSE 12814.07349 12950.63762 13015.52886 13210.31212 13695.12378 16546.2408 17312.17666 8247.591354 12204.71185 10651.09488 1.203075705 1.21589731 1.221989758 1.240277386 1.285794928 1.553477927 1.625389394 0.774342116 1.145864531 1 13.37871412 -8.149069028 0.392225352 0.977840733 1.335795031 0.104397944 0.218416175 1.380953173 0.513598493 0.203828933 0.101143811 7.09E-09 8.149069028 0.357954298 GGPASVPSSS(ph)PGTSVK ddPTM_HeLa_Curcumin_4h_R1 1 GGPASVPSSSPGTSVK 16 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 0 GGPASVPS(0.006)S(0.234)S(0.759)PGT(0.001)SVK 191.06 3.88E-07 14949000 7660.2 6339.4 6371.6 7159.5 7589.4 10672 8926.7 3135.3 6780.1 5408.2 TRUE FALSE FALSE 7053.887087 6887.349488 6607.737101 7129.875886 7498.901362 8458.506902 9177.159177 4091.238537 6036.339993 5596.134547 1.260492761 1.230733362 1.18076809 1.274071562 1.340014486 1.511490982 1.639910388 0.731082947 1.078662413 1 12.45021493 -9.225580288 0.367664451 0.899047346 1.321759638 0.135979631 0.225610212 3.259396762 0.59053718 0.557733693 0.088402577 5.95E-10 9.225580288 0.422712291 GGPEGVAAQAVASAAS(ph)AGPADAEMEEIFDDASPGKQK ddPTM_HeLa_Curcumin_4h_R1 1 GGPEGVAAQAVASAASAGPADAEMEEIFDDASPGKQK 37 1 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 1 0 GGPEGVAAQAVAS(0.131)AAS(0.507)AGPADAEMEEIFDDAS(0.362)PGKQK 61.228 8.53E-05 13625000 1335.3 991.92 1524.4 1450.8 1554.2 1540.3 1200.5 910.8 1424.7 1148.6 TRUE FALSE FALSE 1229.609596 1077.657145 1580.895605 1444.796974 1535.66718 1220.824417 1234.182799 1188.498727 1268.413974 1188.513765 1.034577497 0.906726684 1.330144969 1.215633354 1.292090362 1.027185762 1.038425331 0.999987348 1.067226996 1 10.2149429 -6.783517245 24.99994248 1.008564392 1.14926084 0.302468882 0.110252636 241.5846123 273558.1414 0.018334399 0.02410671 1.65E-07 6.783517245 0.140696448 GGPEGVAAQAVASAASAGPADAEMEEIFDDAS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 2 GGPEGVAAQAVASAASAGPADAEMEEIFDDASPGK 35 0 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 1 0 GGPEGVAAQAVASAASAGPADAEMEEIFDDAS(1)PGK;GGPEGVAAQAVASAAS(0.002)AGPADAEMEEIFDDAS(0.998)PGK ; 139.88 9.01E-18 4973000 4023.49 3747.62 5222.6 4883.83 6466 4950.1 4390.45 3058.41 4153.25 3761.17 TRUE FALSE FALSE 3705.026521 4071.547574 5416.15415 4863.622006 6388.897173 3923.393461 4513.634211 3990.90513 3697.648866 3891.870378 0.951991244 1.046167313 1.391658412 1.249687562 1.64160071 1.008099726 1.159759646 1.02544657 0.950095586 1 11.92624795 -6.925479647 6.454337407 0.978378803 1.248821305 0.360590306 0.171059868 0.173024898 11.94280519 0.027394507 0.036082281 1.19E-07 6.925479647 0.270442503 GGPEGVAAQAVASAASAGPADAEMEEIFDDAS(ph)PGKQK ddPTM_HeLa_Curcumin_4h_R1 1 GGPEGVAAQAVASAASAGPADAEMEEIFDDASPGKQK 37 1 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 1 0 GGPEGVAAQAVAS(0.002)AAS(0.006)AGPADAEMEEIFDDAS(0.993)PGKQK 64.614 2.85E-05 14702000 1912.2 1243.4 1532.4 1958.5 1660.4 1917.7 1575.8 1060.2 1714.1 1705.3 TRUE FALSE FALSE 1760.847352 1350.873956 1589.192092 1950.396246 1640.600814 1519.947403 1620.012707 1383.450099 1526.067518 1764.559048 0.997896531 0.765558941 0.900617122 1.105316508 0.929751156 0.8613752 0.918083591 0.784020292 0.864843554 1 10.78509199 -1.000000024 0.229929744 1.004044216 5.46E-11 0.010780946 0.097236592 50.85743586 0.618529866 0.060458774 19.41647096 0.099999995 1.000000024 -1.004044216 GGPGAAPGGAS(ph)PASSSSAAS(ph)SPSSGR ddPTM_HeLa_Curcumin_4h_R1 1 GGPGAAPGGASPASSSSAASSPSSGR 26 0 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 2 0 GGPGAAPGGAS(0.547)PAS(0.44)S(0.023)S(0.007)S(0.035)AAS(0.837)S(0.071)PS(0.034)S(0.005)GR 141.69 1.97E-07 3721200 1571.9 1207.6 1109.1 1573.4 1427.9 1873.9 1741.4 462.17 1299.4 904.56 TRUE FALSE FALSE 1447.482456 1311.979563 1150.204222 1566.889688 1410.873225 1485.232017 1790.258997 603.0835054 1156.859071 935.9933927 1.546466532 1.401697462 1.228859339 1.674039261 1.50735383 1.586797544 1.912683371 0.644324533 1.235969271 1 9.870354535 -9.345273201 0.817989639 0.965392647 1.468190697 0.112689033 0.324427123 0.839185428 0.89181705 0.281637873 0.056572546 4.52E-10 9.345273201 0.50279805 GGPGAAPGGAS(ph)PASSSSAASS(ph)PSSGR ddPTM_HeLa_Curcumin_4h_R1 1 GGPGAAPGGASPASSSSAASSPSSGR 26 0 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 2 0 GGPGAAPGGAS(0.998)PAS(0.001)S(0.001)SSAAS(0.175)S(0.386)PS(0.35)S(0.089)GR 136.96 1.91E-07 4127500 3434 2941.6 3160.5 3401.7 3749.3 4448.6 3719.3 920.78 3350.4 2072.7 TRUE FALSE FALSE 3162.195276 3195.858796 3277.63091 3387.624667 3704.592046 3525.910214 3823.653548 1201.521583 2982.869502 2144.726171 1.474405134 1.490101086 1.528228151 1.579513839 1.727303045 1.643990856 1.78281666 0.56022144 1.3907927 1 11.06657775 -8.983797972 0.684397541 0.979190572 1.509583993 0.042212156 0.344303687 0.835594954 0.685908823 0.246374101 0.067150115 1.04E-09 8.983797972 0.530393421 GGPGAAPGGASPAS(ph)SSSAASSPSSGR ddPTM_HeLa_Curcumin_4h_R1 1 GGPGAAPGGASPASSSSAASSPSSGR 26 0 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 1 0 GGPGAAPGGAS(0.226)PAS(0.36)S(0.36)S(0.02)SAAS(0.032)S(0.002)PSSGR 253.58 5.83E-54 29511000 5468.1 4411.2 4781 5321.4 5626.2 6448.2 4888.5 1593 5578.3 4795.2 TRUE FALSE FALSE 5035.294115 4792.484472 4958.188066 5299.381457 5559.11124 5110.770634 5025.658153 2078.698367 4966.374446 4961.832843 1.014805269 0.965869795 0.999265437 1.068029018 1.12037455 1.030016688 1.012863253 0.418937605 1.000915308 1 12.27665742 -4.261457421 8.118711322 1.017474094 0.414425705 0.951148127 0.041088763 0.014677555 12.46364559 0.006095903 0.048233777 5.48E-05 4.261457421 -0.60304839 GGPGAAPGGASPAS(ph)SSSAASSPSSGRAPGAAPSAAAK ddPTM_HeLa_Curcumin_4h_R1 1 GGPGAAPGGASPASSSSAASSPSSGRAPGAAPSAAAK 37 1 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 1 0 GGPGAAPGGAS(0.021)PAS(0.164)S(0.164)S(0.164)S(0.164)AAS(0.159)S(0.146)PS(0.013)S(0.005)GRAPGAAPS(0.001)AAAK 50.972 0.0024008 4760900 1929.6 961.38 1161.4 1444.1 1319.4 1696.4 1566.1 508.59 2179.2 1569.7 TRUE FALSE FALSE 1776.870124 1044.477403 1204.442506 1438.124697 1303.667017 1344.547518 1610.040551 663.6567497 1940.147212 1624.246958 1.093965493 0.643053323 0.741539025 0.885410122 0.802628572 0.827797467 0.991253542 0.4085935 1.194490285 1 10.66555529 -7.272415823 24.98273304 1.044372599 0.774979052 0.488148501 0.155643404 476.6197499 1084799.635 0.023762867 0.027312136 5.34E-08 7.272415823 -0.269393547 GGPGAAPGGASPASSSSAASS(ph)PSSGR ddPTM_HeLa_Curcumin_4h_R1 1 GGPGAAPGGASPASSSSAASSPSSGR 26 0 Q9BXK1 Q9BXK1 KLF16 Krueppel-like factor 16 1 0 GGPGAAPGGASPASSSSAAS(0.098)S(0.872)PS(0.027)S(0.003)GR 351.68 9.93E-188 28726000 1852.1 1196.8 1655.4 1616.1 1687.7 1751.6 1664.1 570.65 1307.8 1118.5 TRUE FALSE FALSE 1705.504331 1300.246059 1716.75058 1609.413006 1667.57528 1388.298415 1710.790167 744.6385581 1164.337612 1157.367792 1.47360618 1.123451049 1.483323272 1.390580434 1.440834359 1.199530888 1.478173299 0.643389736 1.006022131 1 10.17663169 -1.408621229 16.7289527 1.248728963 0.016522062 0 0.268439671 0 0 0.034852237 0 0.039028222 1.408621229 -1.232206902 GGPGK(ac)MDKGEHR ddPTM_HeLa_Curcumin_4h_R1 1 GGPGKMDKGEHR 12 2 H7BY36;A0A0D9SFL3;B0QYK0;C9JGE3;Q01844-2;Q01844-6;Q01844-3;Q01844;Q01844-5 H7BY36 EWSR1 RNA-binding protein EWS 0 1 GGPGK(0.986)MDK(0.014)GEHR 69.721 0.014264 967610 1872.7 1487.1 1588.6 1504.2 1149.6 1913.7 879.56 997.25 1795.3 1445.9 FALSE TRUE FALSE 1724.473819 1615.638298 1647.474913 1497.976019 1135.891771 1516.777048 904.2380864 1301.306934 1598.360082 1496.144917 1.152611488 1.079867517 1.101146616 1.00122388 0.759212398 1.013790195 0.604378677 0.869773321 1.068319026 1 10.54703421 -5.899319216 4.133536979 1.075899785 0.811766564 0.609351379 0.101550738 0.116627007 3.67678918 0.015322539 0.028579848 1.26E-06 5.899319216 -0.264133221 GGPGSAVS(ph)PYPTFNPSSDVAALHK ddPTM_HeLa_Curcumin_4h_R1 3 GGPGSAVSPYPTFNPSSDVAALHK 24 0 P04083;Q5T3N1;Q5T3N0 P04083 ANXA1 Annexin A1;Annexin 1 0 GGPGS(0.002)AVS(0.998)PYPTFNPSSDVAALHK;GGPGS(0.384)AVS(0.485)PY(0.124)PT(0.006)FNPSSDVAALHK;GGPGS(0.004)AVS(0.968)PY(0.017)PT(0.01)FNPSSDVAALHK ;; 173.18 2.08E-10 229213000 7184.9 6034.6 5897.63 6379.24 6975.03 11412.4 6995 8720.11 8037.1 6395.41 TRUE FALSE FALSE 6616.207584 6556.203934 6116.201356 6352.844395 6891.857323 9045.339596 7191.260874 11378.8314 7155.450238 6617.650021 0.999782032 0.990714818 0.924225569 0.959984945 1.041435751 1.366850705 1.086678934 1.719467086 1.081267552 1 12.69210328 -1.000000001 0.677043014 0.9921287 74.05099724 0.781759875 0.108406779 69.8542011 0.378036433 0.016080319 7706.229927 0.1 1.000000001 73.05886854 GGPGSTLSFVGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 GGPGSTLSFVGKR 13 1 Q9BQ61 Q9BQ61 C19orf43 Uncharacterized protein C19orf43 0 1 GGPGSTLSFVGK(1)R 165.63 3.54E-06 2793800 358.27 357.69 210.14 278.65 277.9 393.1 219.08 359.28 307.66 322.02 FALSE TRUE FALSE 329.9125515 388.6071298 217.9279733 277.4970201 274.586224 311.5666288 225.2267952 468.8228181 273.9104677 333.210171 0.990103485 1.166252304 0.654025574 0.832798769 0.824063153 0.935045374 0.675930133 1.406988318 0.822035134 1 8.380288629 -6.779333387 24.99871966 1.008015455 0.875199517 0.054792804 0.209626483 422.2453216 589893.692 0.029538463 0.038865551 1.66E-07 6.779333387 -0.132815938 GGPPFAFVEFEDPRDAEDAVYGR ddPTM_HeLa_Curcumin_4h_R1 2 GGPPFAFVEFEDPRDAEDAVYGR 23 1 J3KTL2;Q07955;Q07955-3;Q07955-2 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 0 ; ; 111.63 9.76E-06 91026000 743.26 550.83 830.78 620.08 676.54 1354.05 859.48 696.72 749.79 706.74 FALSE FALSE TRUE 684.4301867 598.4412907 861.5694376 617.5142733 668.4727024 1073.204767 883.5946956 909.1467207 667.5399129 731.2991624 0.935909983 0.818326236 1.178135409 0.844407193 0.914089249 1.467531787 1.208253395 1.243193986 0.912813726 1 9.514317899 -5.274980096 24.96023286 0.96061774 1.296519093 0.682549939 0.112941152 309.268719 570089.146 0.014938144 0.03357602 5.31E-06 5.274980096 0.335901352 GGPPSQGGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GGPPSQGGKR 10 1 Q15050 Q15050 RRS1 Ribosome biogenesis regulatory protein homolog 0 1 ; GGPPSQGGK(1)R;GGPPSQGGK(1)R 96.143 0.0049902 460200 0 0 0 0 0 74.212 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 58.81959466 0 0 0 0 0 GGPS(ph)PGDVEAIK ddPTM_HeLa_Curcumin_4h_R1 2 GGPSPGDVEAIK 12 0 P09661;H0YLR3;H0YMA0 P09661 SNRPA1 U2 small nuclear ribonucleoprotein A 1 0 GGPS(1)PGDVEAIK;GGPS(1)PGDVEAIK ; 142.38 0.0010547 21083900 5305.2 4255 4773 5088.7 5243.4 6126.5 4678.6 4993.4 4730 4525.6 TRUE FALSE FALSE 4885.287822 4622.78324 4949.891579 5067.644308 5180.87588 4855.79484 4809.868924 6515.864673 4211.130834 4682.864263 1.043226442 0.987170027 1.05702222 1.08216767 1.106347651 1.036928377 1.027121149 1.391427192 0.899263911 1 12.19317551 -4.260935943 24.8806874 1.032299716 1.391427309 0.801874834 0.054338968 9.128380026 451002.6492 0.005414195 0.042844016 5.48E-05 4.260935943 0.359127593 GGQGDPAVPAQQPADPS(ph)TPERQSSPSGS(ph)EQLVR ddPTM_HeLa_Curcumin_4h_R1 1 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-3;H0Y704;O15231-2;H7BZT5;O15231-4;O15231-7;O15231;O15231-8;O15231-6;O15231-9;O15231-5 O15231-3 ZNF185 Zinc finger protein 185 2 0 GGQGDPAVPAQQPADPS(0.412)T(0.412)PERQS(0.182)S(0.182)PS(0.136)GS(0.677)EQLVR 74.973 7.00E-06 54847000 3399.2 2777.5 2755.7 3034.8 2640.2 3540.6 2700.9 2134.9 4165.3 3208 TRUE FALSE FALSE 3130.149733 3017.574724 2857.828666 3022.242802 2608.717339 2806.239649 2776.679985 2785.821182 3708.377011 3319.477761 0.942964514 0.909051044 0.860927191 0.910457313 0.785881855 0.845385886 0.836480972 0.839234778 1.117156757 1 11.69674057 -7.064298931 0.524348562 0.993239276 0.823671666 0.725980803 0.048041653 0.201483228 0.126094671 0.008833131 0.012343724 8.62E-08 7.064298931 -0.16956761 GGQGDPAVPAQQPADPS(ph)TPERQSSPSGSEQLVR ddPTM_HeLa_Curcumin_4h_R1 1 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-3;H0Y704;O15231-2;H7BZT5;O15231-4;O15231-7;O15231;O15231-8;O15231-6;O15231-9;O15231-5 O15231-3 ZNF185 Zinc finger protein 185 1 0 GGQGDPAVPAQQPADPS(0.758)T(0.24)PERQS(0.001)SPSGSEQLVR 111.31 1.40E-14 27270000 1746.8 1288.9 1067.9 1493.6 873.03 2121.1 1119.1 1186.3 2186.8 1944.6 TRUE FALSE FALSE 1608.538937 1400.306773 1107.477313 1487.419879 862.6196874 1681.15995 1150.498934 1547.997409 1946.913511 2012.174705 0.799403219 0.695917094 0.550388249 0.739210107 0.428700194 0.835494028 0.571768908 0.769315609 0.967566835 1 10.97453986 -7.967566286 0.72645794 0.973543127 0.643845267 0.5592452 0.114186111 0.28140183 0.328641951 0.037445305 0.027199746 1.08E-08 7.967566286 -0.32969786 GGQGDPAVPAQQPADPST(ph)PER ddPTM_HeLa_Curcumin_4h_R1 2 GGQGDPAVPAQQPADPSTPER 21 0 O15231-3;H0Y704;O15231-2;H7BZT5;O15231-4;O15231-7;O15231;O15231-8;O15231-6;O15231-9;O15231-5 O15231-3 ZNF185 Zinc finger protein 185 1 0 GGQGDPAVPAQQPADPS(0.005)T(0.995)PER;GGQGDPAVPAQQPADPS(0.069)T(0.931)PER ; 232.6 4.81E-29 288750000 8826.8 10372 7805 8343.2 9006.9 10091.9 8130.8 6891.2 8755.1 8602.2 TRUE FALSE FALSE 8128.149466 11268.50946 8094.260166 8308.678049 8899.4986 7998.726181 8358.928365 8992.295157 7794.687434 8901.12581 0.91315971 1.26596452 0.909352405 0.933441255 0.999817191 0.898619607 0.939086644 1.010242451 0.875696805 1 13.1197721 GGQGDPAVPAQQPADPST(ph)PERQSSPSGS(ph)EQLVR ddPTM_HeLa_Curcumin_4h_R1 1 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-3;H0Y704;O15231-2;H7BZT5;O15231-4;O15231-7;O15231;O15231-8;O15231-6;O15231-9;O15231-5 O15231-3 ZNF185 Zinc finger protein 185 2 0 GGQGDPAVPAQQPADPS(0.38)T(0.417)PERQS(0.245)S(0.242)PS(0.17)GS(0.547)EQLVR 70.811 3.29E-05 57781000 1954.9 1740.3 1595.3 2071.8 1819.4 2194.3 1884.2 1362.2 2485.6 1790.2 TRUE FALSE FALSE 1800.167602 1890.723777 1654.423221 2063.227441 1797.704843 1739.177445 1937.065581 1777.528509 2212.935899 1852.409317 0.971797964 1.020683582 0.893119683 1.113807527 0.970468474 0.93887319 1.045700625 0.959576533 1.194625766 1 10.8551872 GGQGDPAVPAQQPADPST(ph)PERQSSPSGSEQLVR ddPTM_HeLa_Curcumin_4h_R1 1 GGQGDPAVPAQQPADPSTPERQSSPSGSEQLVR 33 1 O15231-3;H0Y704;O15231-2;H7BZT5;O15231-4;O15231-7;O15231;O15231-8;O15231-6;O15231-9;O15231-5 O15231-3 ZNF185 Zinc finger protein 185 1 0 GGQGDPAVPAQQPADPS(0.28)T(0.696)PERQS(0.014)S(0.006)PS(0.002)GS(0.002)EQLVR 87.704 4.02E-08 19676000 1897.4 1212.8 1036.3 1704.4 1080.7 1872.7 1342.1 1044.4 2155.7 1546.3 TRUE FALSE FALSE 1747.218788 1317.629028 1074.70619 1697.347644 1067.813358 1484.28091 1379.755714 1362.832752 1919.225103 1600.03381 1.091988667 0.823500741 0.671677175 1.060819861 0.667369247 0.927655966 0.862329099 0.851752472 1.199490343 1 10.64388668 -7.255582714 24.87616122 1.043439094 0.837890957 0.479161755 0.120021742 288.7832002 1226605.876 0.0171186 0.020660321 5.55E-08 7.255582714 -0.205548137 GGQGDPAVPTQQPADPST(ph)PEQQNS(ph)PSGSEQFVR ddPTM_HeLa_Curcumin_4h_R1 2 GGQGDPAVPTQQPADPSTPEQQNSPSGSEQFVR 33 0 O15231-3;H0Y704;O15231-2;H7BZT5;O15231-4;O15231-7;O15231;O15231-8;O15231-6;O15231-9;O15231-5 O15231-3 ZNF185 Zinc finger protein 185 2 0 GGQGDPAVPT(0.005)QQPADPS(0.454)T(0.542)PEQQNS(0.886)PS(0.105)GS(0.009)EQFVR;GGQGDPAVPT(0.004)QQPADPS(0.133)T(0.863)PEQQNS(0.828)PS(0.154)GS(0.018)EQFVR ; 128.47 1.01E-17 38512000 8064.3 6557.9 6730.6 6611.5 7738.7 8744.9 6252.9 4561.3 6984.1 6331.2 TRUE FALSE FALSE 7426.002146 7124.735655 6980.041957 6584.143365 7646.421057 6931.109165 6428.339545 5952.019372 6217.961703 6551.208729 1.133531605 1.087545207 1.065458642 1.005027261 1.167177138 1.057989365 0.981244807 0.908537587 0.949131979 1 12.6775454 -4.569755974 2.644023941 1.069430077 0.912649922 0.370660162 0.061332809 0.217479175 2.761624977 0.008437991 0.055188601 2.69E-05 4.569755974 -0.156780156 FGNPGEK(ac)LVK ddPTM_HeLa_Curcumin_4h_R1 2 FGNPGEKLVK 10 1 P17844-2;P17844;J3KTA4;J3QRQ7;J3QR02;J3KRX8;J3KTQ4;X6RLV5;J3QKN9 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 1 ; FGNPGEK(1)LVK;FGNPGEK(1)LVK 160.53 5.79E-09 67687000 9439 7714.4 8664.9 7450.4 7399.3 10742.8 9947.3 12300.2 9119.8 7321.7 FALSE TRUE FALSE 8691.89319 8381.198361 8986.028816 7419.572219 7311.06818 8514.622184 10226.39447 16050.47436 8119.380757 7576.12853 1.147273724 1.106264014 1.186097725 0.979335579 0.965013747 1.123875097 1.349817974 2.118558878 1.071705783 1 12.88724509 -4.228461194 1.935326246 1.069487291 2.497512144 0.95543539 0.068206024 0.14288382 0.517724541 0.011514511 0.373773169 5.91E-05 4.228461194 1.428024853 up GGREGFES(ph)DTDSEFTFK ddPTM_HeLa_Curcumin_4h_R1 2 GGREGFESDTDSEFTFK 17 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;E9PMP7 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 GGREGFES(0.932)DT(0.066)DS(0.002)EFTFK;GGREGFES(0.874)DT(0.027)DS(0.094)EFT(0.005)FK ; 88.983 0.0020963 54331000 9979.1 7210.1 7805.8 8826.4 8186.5 9871.1 6983.8 3942.7 10576.7 8962.6 TRUE FALSE FALSE 9189.243705 7833.308916 8095.089815 8789.878695 8088.881334 7823.72259 7179.746632 5144.81108 9416.462472 9274.049683 0.990855561 0.844648151 0.872875399 0.947792927 0.872205952 0.843614479 0.774175994 0.554753452 1.015356052 1 13.17898374 -3.431272252 0.402464529 0.992111508 2.16E-26 0.832836417 0.053084362 2.774286753 0.186961927 0.014116141 1.527732427 0.000370448 3.431272252 -0.992111508 GGRS(ph)PDEVTLTSIVPTR ddPTM_HeLa_Curcumin_4h_R1 2 GGRSPDEVTLTSIVPTR 17 1 A0A0C4DGG1;Q9UKS6;H0YDM6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 0 GGRS(1)PDEVTLTSIVPTR;GGRS(1)PDEVTLTSIVPTR ; 90.453 0.0017649 35331000 2228.27 2270.17 2069.36 1773.84 1863.17 3207.2 2626.4 2047.32 2512.31 2863.3 TRUE FALSE FALSE 2051.900078 2466.393379 2146.052302 1766.50032 1840.952915 2541.990567 2700.089715 2671.538443 2236.715878 2962.799462 0.692554493 0.832453702 0.724332622 0.596226759 0.621355896 0.857969161 0.911330568 0.901693982 0.754933267 1 11.53274526 -9.385030559 1.031442841 1.004410435 0.759657355 0 0.128444157 0.472878622 0.873727122 0.08685683 0.020727779 4.12E-10 9.385030559 -0.244753081 GGRSPDEVTLT(ph)SIVPTR ddPTM_HeLa_Curcumin_4h_R1 1 GGRSPDEVTLTSIVPTR 17 1 A0A0C4DGG1;Q9UKS6;H0YDM6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 0 GGRS(0.008)PDEVT(0.259)LT(0.558)S(0.173)IVPT(0.002)R 144.08 0.0028667 37159000 1066.9 913.42 1054.7 981.56 1289.8 1495.4 1072.5 1034.9 1102.7 1036.9 TRUE FALSE FALSE 982.4537392 992.3719547 1093.78811 977.4985648 1274.419977 1185.237183 1102.591464 1350.436246 981.7365688 1072.932198 0.915671784 0.924915812 1.019438239 0.911053435 1.187791717 1.104671093 1.027643187 1.258640806 0.915003363 1 10.06734319 -5.762866555 25 0.958180592 1.133468202 0.68069587 0.065686848 18.09112585 316913.4512 0.009353613 0.017645555 1.73E-06 5.762866555 0.17528761 GGS(ph)DGYGSGR ddPTM_HeLa_Curcumin_4h_R1 2 GGSDGYGSGR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 0 GGS(1)DGYGSGR;GGS(0.995)DGYGS(0.005)GR ; 102.05 0.011218 15939800 6064.3 10628.8 6530.2 5637.5 5099.5 4833.9 4539.2 3454.7 4894.3 7134.3 TRUE FALSE FALSE 5584.304256 11547.50611 6772.214957 5614.173519 5038.691793 3831.294651 4666.557735 4508.022127 4357.407535 7382.216394 0.756453612 1.564232948 0.917368795 0.760499722 0.682544581 0.518989751 0.632135051 0.610659711 0.590257357 1 12.84983831 -5.955877778 2.375725189 0.944479146 0.600810404 0.33320123 0.236942172 0.268467567 3.057847754 0.03477646 0.067465177 1.11E-06 5.955877778 -0.343668742 GGS(ph)PDLWK ddPTM_HeLa_Curcumin_4h_R1 4 GGSPDLWK 8 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 GGS(1)PDLWK;GGS(1)PDLWK;GGS(1)PDLWK;GGS(1)PDLWK ;;; 114.86 0.0098759 695510000 26280.8 21909.8 24227 24183 23907.1 26147.2 21845.6 13075.8 27391.4 23408.9 TRUE FALSE FALSE 24200.64695 23803.58548 25124.87393 24082.93715 23622.02345 20723.97598 22458.52874 17062.55123 24386.63195 24222.35753 0.999103696 0.982711342 1.037259643 0.994244145 0.975215704 0.855572211 0.927181787 0.704413317 1.006781933 1 14.56405167 -3.361018982 0.66807931 1.00166168 1.39E-19 0.85635625 0.035781722 2.071483728 0.268503652 0.005523204 2.093285237 0.000435493 3.361018982 -1.00166168 GGS(ph)PQMDDIK ddPTM_HeLa_Curcumin_4h_R1 1 GGSPQMDDIK 10 0 A0A3B3ITG6;A0A3B3IUB1;Q13144 A0A3B3ITG6 EIF2B5 Translation initiation factor eIF-2B subunit epsilon 1 0 GGS(1)PQMDDIK 90.697 0.018751 41853000 2792 2831.9 3386.8 2675.2 3668.6 2373.2 2246.7 2327 2272.5 2793.3 TRUE FALSE FALSE 2571.010254 3076.676817 3512.317787 2664.130731 3624.854341 1880.971569 2309.736355 3036.491588 2023.212436 2890.366967 0.889509977 1.064458891 1.215180573 0.921727504 1.254115613 0.65077258 0.799115262 1.050555733 0.699984624 1 11.49703696 -5.241773622 24.99851647 0.991903752 0.830044645 0.166761773 0.175009618 1070.080297 1360251.653 0.021135662 0.053802626 5.73E-06 5.241773622 -0.161859107 VDDSTGTVIS(ph)DVEEDAGELSR ddPTM_HeLa_Curcumin_4h_R1 2 VDDSTGTVISDVEEDAGELSR 21 0 Q9Y2D8-2;Q9Y2D8-3;Q9Y2D8;S4R403 Q9Y2D8-2 SSX2IP Afadin- and alpha-actinin-binding protein 1 0 VDDST(0.003)GT(0.012)VIS(0.972)DVEEDAGELS(0.013)R;VDDST(0.006)GTVIS(0.994)DVEEDAGELSR ; 209.23 9.96E-18 23474000 1226.44 1355.56 1476.36 1436.94 1584.28 1661.97 757.46 322.055 1293.62 1347.71 TRUE FALSE FALSE 1129.36598 1472.728566 1531.0752 1430.994323 1565.388496 1317.258688 778.712289 420.2480869 1151.713122 1394.542822 0.809846755 1.056065502 1.097904758 1.026138674 1.122510167 0.944581025 0.558399697 0.30135187 0.825871464 1 10.44557652 -4.607318545 2.825295678 0.958584206 0.325117168 0.832054576 0.102289058 0.096360941 1.43828184 0.017181116 0.097550161 2.47E-05 4.607318545 -0.633467038 down GGS(ph)SKDLLDNQSQEEQR ddPTM_HeLa_Curcumin_4h_R1 1 GGSSKDLLDNQSQEEQR 17 1 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 0 GGS(0.829)S(0.171)KDLLDNQSQEEQR 54.768 0.019396 13692000 2137.1 2044 1829.2 1860.4 3037.3 2400.8 1654.5 1152.3 2279.6 2097.4 TRUE FALSE FALSE 1967.94628 2220.674252 1896.991761 1852.702158 3001.082181 1902.847017 1700.920817 1503.630965 2029.533583 2170.284494 0.906768806 1.023218043 0.874075158 0.853667878 1.38280589 0.876773079 0.783731728 0.692826664 0.935146332 1 11.08366846 -4.810642025 3.659164129 0.975017669 0.72880037 0.330243442 0.143751563 0.195879273 5.295566502 0.019489647 0.071317624 1.55E-05 4.810642025 -0.246217298 GGS(ph)SKDLLDNQSQEEQRR ddPTM_HeLa_Curcumin_4h_R1 1 GGSSKDLLDNQSQEEQRR 18 2 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 0 GGS(0.5)S(0.5)KDLLDNQSQEEQRR 100.01 0.00108 48927000 1437.4 1185 1370 1177.1 1189.7 1919.6 1745.4 1080.1 1422.6 1313 TRUE FALSE FALSE 1323.628273 1287.42612 1420.773405 1172.229472 1175.513605 1521.453322 1794.371226 1409.417518 1266.544339 1358.626652 0.974239885 0.947593747 1.045742333 0.862804708 0.865221952 1.119846515 1.320724294 1.037383976 0.932223976 1 10.40793335 -5.049354195 7.169740679 0.972718771 1.189324871 0.560263515 0.085074083 0.121616951 15.27769981 0.011092998 0.028938345 8.93E-06 5.049354195 0.216606099 GSVSSVS(ph)PKPPSSFK ddPTM_HeLa_Curcumin_4h_R1 1 GSVSSVSPKPPSSFK 15 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 0 GSVS(0.063)S(0.214)VS(0.723)PKPPSSFK 180.56 0.00053023 20012000 1981.2 1350.2 1633.3 1877.5 1722.4 1624.7 977.08 109 1793.1 1919.8 TRUE FALSE FALSE 1824.385929 1466.905272 1693.831535 1869.731402 1701.861505 1287.718906 1004.494235 142.2335982 1596.401416 1986.512907 0.918386144 0.738432288 0.852665759 0.941212814 0.856708003 0.648230828 0.505657039 0.071599635 0.803619957 1 10.95602245 -4.598721496 1.084610351 0.934070725 1.13E-18 0.877024712 0.091443479 0.237041615 0.31944707 0.013908168 0.220050149 2.52E-05 4.598721496 -0.934070725 down QLVYVEQAGSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 QLVYVEQAGSSPK 13 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 0 QLVYVEQAGS(0.079)S(0.921)PK;QLVYVEQAGS(0.081)S(0.919)PK ; 227.91 2.23E-19 60295000 8489 7059.6 8449.7 8108.9 7855 6623.4 4749.5 1582.42 9506.9 7540 TRUE FALSE FALSE 7817.086692 7669.800367 8762.853315 8075.34752 7761.334255 5249.632179 4882.758187 2064.892573 8464.016855 7802.014439 1.001931841 0.983053855 1.123152666 1.035033655 0.994785938 0.672855994 0.625833011 0.264661465 1.084850191 1 12.92963095 -4.596784554 1.078924732 1.014365635 0.149520095 0.930503537 0.067946824 0.181076783 0.240252439 0.009716574 0.155187107 2.53E-05 4.596784554 -0.864845541 down GGSDGTPRGSPS(ph)PASVSSGR ddPTM_HeLa_Curcumin_4h_R1 1 GGSDGTPRGSPSPASVSSGR 20 1 Q96II5;P10398 Q96II5 ARAF Serine/threonine-protein kinase A-Raf 1 0 GGSDGT(0.008)PRGS(0.054)PS(0.938)PAS(0.001)VSSGR 180.39 1.36E-06 4995500 1025.7 1091 938.99 880.91 1000.2 1371.8 983.7 167.54 1440.8 1067.2 TRUE FALSE FALSE 944.5147627 1185.301179 973.7897954 877.2650278 988.2732683 1087.273217 1011.299975 218.6221747 1282.747845 1104.285121 0.855317839 1.073365163 0.881828232 0.794418952 0.894943932 0.984594645 0.915796071 0.197976203 1.161609281 1 10.108897 -4.261642356 6.946147126 0.92804411 0.186868038 0.820876137 0.105083101 0.0265501 9.471416049 0.011301432 0.092086048 5.47E-05 4.261642356 -0.741176073 GGSFWSSIPAS(ph)PASRPGSFTFPGDSDSLQR ddPTM_HeLa_Curcumin_4h_R1 1 GGSFWSSIPASPASRPGSFTFPGDSDSLQR 30 1 E7EPJ7;O75962-5;O75962-4;O75962 E7EPJ7 TRIO Triple functional domain protein 1 0 GGSFWS(0.002)S(0.008)IPAS(0.691)PAS(0.208)RPGS(0.036)FT(0.016)FPGDS(0.026)DS(0.014)LQR 59.011 0.00090802 15510000 622.86 529.32 649.91 321.16 441.84 4680.2 3105.8 3338.6 742.87 829.49 TRUE FALSE FALSE 573.5599738 575.0720622 673.9962363 319.831125 436.5713466 3709.473763 3192.940389 4356.523771 661.3790196 858.3147158 0.668239707 0.670001401 0.785255366 0.372626869 0.508637844 4.321810747 3.720011239 5.075671768 0.770555377 1 9.745362923 -5.259045498 24.98807379 0.766649258 4.307249497 0.958639005 0.350884152 28.3879927 296320.2033 0.048962405 0.118626538 5.51E-06 5.259045498 3.54060024 GGSGS(ph)GPTIEEVD ddPTM_HeLa_Curcumin_4h_R1 2 GGSGSGPTIEEVD 13 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 1 0 GGS(0.056)GS(0.944)GPTIEEVD;GGS(0.08)GS(0.92)GPTIEEVD ; 134.3 0.0013643 23177000 4146.8 3894.3 4117.2 4511.4 4734 5553.5 4221.6 4093 4572.8 3751.7 TRUE FALSE FALSE 3818.576404 4230.905939 4269.787054 4492.733022 4677.550142 4401.641499 4340.046734 5340.936858 4071.175281 3882.071296 0.983644069 1.089857866 1.099873425 1.157303068 1.204910932 1.133838398 1.117971929 1.375795665 1.048712136 1 11.9226109 -6.520379444 0.774678586 0.988148425 1.213531868 0.591618126 0.068112636 0.262508269 0.315149513 0.013189075 0.025851988 3.02E-07 6.520379444 0.225383442 GGSGS(ph)VLQDEEVLASLER ddPTM_HeLa_Curcumin_4h_R1 2 GGSGSVLQDEEVLASLER 18 0 A0A0D9SG79;Q9NZ09-2;Q9NZ09;Q9NZ09-3;Q9NZ09-4 A0A0D9SG79 UBAP1 Ubiquitin-associated protein 1 1 0 GGS(0.069)GS(0.931)VLQDEEVLASLER;GGS(0.004)GS(0.89)VLQDEEVLAS(0.106)LER ; 145.9 1.13E-06 2507000 2033.58 1319.93 1711.91 1728.43 1729.19 2279.4 1643.74 1710.21 2023.34 1816.08 TRUE FALSE FALSE 1872.619997 1434.018868 1775.354891 1721.278215 1708.570539 1806.626746 1689.858921 2231.645156 1801.384664 1879.188645 0.99650453 0.763105328 0.944745433 0.915968825 0.909206504 0.961386581 0.899249219 1.187557812 0.958597036 1 10.87589419 -3.160147835 13.55214763 0.96991254 0.954815719 0 0.102065491 0 0 0.013007614 0 0.000691596 3.160147835 -0.015096821 GGSGSVLQDEEVLAS(ph)LER ddPTM_HeLa_Curcumin_4h_R1 1 GGSGSVLQDEEVLASLER 18 0 A0A0D9SG79;Q9NZ09-2;Q9NZ09;Q9NZ09-3;Q9NZ09-4 A0A0D9SG79 UBAP1 Ubiquitin-associated protein 1 1 0 GGS(0.003)GS(0.001)VLQDEEVLAS(0.996)LER 70.02 0.014315 2391900 511.92 271.41 490.5 472.16 465.54 489.88 345.35 702.89 478.26 439.86 TRUE FALSE FALSE 471.4009918 294.869471 508.6783615 470.206327 459.9887396 388.2733659 355.0395915 917.1979253 425.7960745 455.1451023 1.03571584 0.647858166 1.117618006 1.03309104 1.010641963 0.853076006 0.780058029 2.015176964 0.935517206 1 8.830182746 -4.254757075 24.99171158 0.97720333 2.015177437 0.843164399 0.138701541 220.1828151 823458.5872 0.018705 0.242601505 5.56E-05 4.254757075 1.037974107 GGSISVQVNSIKFDS(ph)E ddPTM_HeLa_Curcumin_4h_R1 6 GGSISVQVNSIKFDSE 16 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 0 GGSISVQVNS(0.052)IKFDS(0.948)E;GGSISVQVNSIKFDS(1)E;GGSISVQVNS(0.001)IKFDS(0.999)E;GGSISVQVNS(0.011)IKFDS(0.989)E;GGSISVQVNS(0.023)IKFDS(0.977)E;GGSISVQVNS(0.004)IKFDS(0.996)E ;;;;; 146.76 0.0026686 1212301900 24664.1 20521 21061 21868.5 19739.1 26360.3 21030.47 20089.3 26179 21958.4 TRUE FALSE FALSE 22711.91046 22294.7438 21841.53919 21778.01394 19503.72412 20892.87664 21620.52839 26214.43509 23307.2292 22721.45277 0.999580031 0.981219996 0.961273886 0.958478059 0.858383675 0.919522042 0.95154692 1.153730589 1.025780765 1 14.47176746 -6.965503903 2.396422598 0.999853822 0.95869345 0.051958442 0.070968471 0.664726473 7.696915096 0.011891465 0.015688879 1.08E-07 6.965503903 -0.041160372 GGSPYNQFDIIPGDT(ph)LGGHTGPAGDSWLPAKSPPTNK ddPTM_HeLa_Curcumin_4h_R1 1 GGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKSPPTNK 37 1 H0Y720;Q9UPQ9-1;Q9UPQ9;Q9UPQ9-2 H0Y720 TNRC6B Trinucleotide repeat-containing gene 6B protein 1 0 GGSPYNQFDIIPGDT(0.461)LGGHT(0.254)GPAGDS(0.058)WLPAKS(0.21)PPT(0.017)NK 66.01 5.30E-06 13480000 864.52 564.05 651.41 534.42 956.92 2105.5 783.47 738.66 1027.8 582.99 TRUE FALSE FALSE 796.0923298 612.8039686 675.5518276 532.2087116 945.509354 1668.795566 805.4520596 963.8740336 915.0529114 603.2488591 1.31967482 1.015839416 1.119855956 0.882237411 1.567362026 2.766346825 1.335190357 1.597804984 1.516874666 1 9.236609472 -5.534952726 10.83249404 1.127711647 1.89714367 0.449118359 0.379257717 0.189741483 164.2923814 0.050845921 0.102869985 2.92E-06 5.534952726 0.769432023 GGSS(ph)KDLLDNQSQEEQR ddPTM_HeLa_Curcumin_4h_R1 1 GGSSKDLLDNQSQEEQR 17 1 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 0 GGS(0.179)S(0.821)KDLLDNQSQEEQR 68.576 0.0092511 7144300 2231.8 2100.3 1994 1788.2 2044.4 2562.7 1825.1 1553.8 2524.5 2367.6 TRUE FALSE FALSE 2055.150675 2281.840573 2067.899394 1780.800902 2020.021865 2031.167132 1876.307394 2027.546467 2247.568666 2449.873924 0.838880179 0.931411429 0.844084005 0.726894917 0.824541151 0.829090474 0.765879165 0.827612575 0.917422176 1 11.25849179 -10.83996341 0.205819362 1.261628066 0.775320077 0.533564086 0.051854056 6.838781396 0.225681616 0.884377045 0.055429346 1.45E-11 10.83996341 -0.48630799 GGTADK(ac)GASANQEKG ddPTM_HeLa_Curcumin_4h_R1 1 GGTADKGASANQEKG 15 2 P55198 P55198 MLLT6 Protein AF-17 0 1 GGTADK(1)GASANQEKG 146.96 0.010537 352630 0 149.2 79.56 70.378 132.67 0 74.009 80.315 0 0 FALSE TRUE FALSE 0 162.0961832 82.50856359 70.08679448 131.0879969 0 76.08549335 104.8026738 0 0 0 GGTLGGGTLGPPSPPGAPS(ph)PPEPGGEIELVFRPHPLLVEK ddPTM_HeLa_Curcumin_4h_R1 1 GGTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEK 40 1 Q06587;Q06587-2 Q06587 RING1 E3 ubiquitin-protein ligase RING1 1 0 GGT(0.001)LGGGT(0.024)LGPPS(0.064)PPGAPS(0.91)PPEPGGEIELVFRPHPLLVEK 53.648 0.00024756 17445000 1026 871.54 1011.1 934.32 1139.4 1296.7 1040.7 901.2 961.12 772.68 TRUE FALSE FALSE 944.7910174 946.8720341 1048.572255 930.4540314 1125.813399 1027.749803 1069.899241 1175.971731 855.6875406 799.5305725 1.181682164 1.184284963 1.311484878 1.16375041 1.408092996 1.285441531 1.338159262 1.470827723 1.070237424 1 9.64300939 -1.000000001 0.051674751 0.416350669 2.831967985 0.793088607 0.063855451 102.5252216 0.40343893 4.399639008 19.64581868 0.1 1.000000001 2.415617316 GGTPAFLPSS(ph)LSPQSSLPASR ddPTM_HeLa_Curcumin_4h_R1 2 GGTPAFLPSSLSPQSSLPASR 21 0 E5RGS7;H0YBP7;B3KPU0;A0A087WVI1;Q96JY6;Q96JY6-3;Q96JY6-5 E5RGS7 PDLIM2 PDZ and LIM domain protein 2 1 0 GGTPAFLPS(0.175)S(0.491)LS(0.334)PQSSLPASR;GGTPAFLPS(0.418)S(0.444)LS(0.128)PQS(0.005)S(0.004)LPAS(0.002)R ; 204.94 2.15E-17 117417000 3732.5 3144.5 3038.3 3551.3 3755.6 5809.9 4398 3617.3 4356 3246.1 TRUE FALSE FALSE 3437.068686 3416.296568 3150.902071 3536.605662 3710.816923 4604.861249 4521.396043 4720.198118 3878.157698 3358.901733 1.023271581 1.017087381 0.938075097 1.052905367 1.104770909 1.370942533 1.346093575 1.405280205 1.154590996 1 11.71377387 -5.372661658 2.242768284 1.007847835 1.382570806 0.882037694 0.055838008 0.036978695 0.359668881 0.004441986 0.012114479 4.24E-06 5.372661658 0.37472297 LEPNS(ph)PMHGGTLLEDVVGGR ddPTM_HeLa_Curcumin_4h_R1 3 LEPNSPMHGGTLLEDVVGGR 20 0 Q5VY60;Q7Z4H7-3;Q7Z4H7 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 0 LEPNS(1)PMHGGTLLEDVVGGR;LEPNS(1)PMHGGTLLEDVVGGR;LEPNS(0.991)PMHGGT(0.009)LLEDVVGGR ;; 96.045 0.00047734 23234500 4109 3795.75 4303.5 3756.17 4730.9 4774.6 4175.4 7475.2 4049.04 3755.11 TRUE FALSE FALSE 3783.768314 4123.837716 4462.991496 3740.627964 4674.487107 3784.294139 4292.550486 9754.354068 3604.870442 3885.599793 0.973792597 1.061313037 1.148597831 0.962689974 1.203028453 0.973927924 1.104733044 2.510385677 0.927751347 1 11.9239216 -4.261123247 4.67890022 1.017456029 2.600021446 0.965942687 0.082922599 0.021195062 1.257233513 0.010848744 0.109358851 5.48E-05 4.261123247 1.582565417 up GGTVS(ph)PPPGTSR ddPTM_HeLa_Curcumin_4h_R1 2 GGTVSPPPGTSR 12 0 Q16584;Q16584-2;E9PID4 Q16584 MAP3K11 Mitogen-activated protein kinase kinase kinase 11 1 0 GGTVS(0.941)PPPGT(0.058)S(0.001)R;GGT(0.001)VS(0.999)PPPGT(0.001)SR ; 108.32 0.0051731 13281000 9474.1 7296.2 7706.4 7448.3 7418.6 7950.5 6169.6 4649 8987.3 8254.8 TRUE FALSE FALSE 8724.214988 7926.851017 7992.005963 7417.480908 7330.13804 6301.476679 6342.702371 6066.458699 8001.415675 8541.653686 1.021373063 0.928022993 0.935650901 0.868389328 0.858163806 0.737734976 0.742561406 0.710220634 0.936752527 1 13.06029969 -5.762010474 0.645672066 1.012106833 0.689751968 0.903398089 0.032775501 0.125275294 0.088488905 0.00488595 0.021055463 1.73E-06 5.762010474 -0.322354864 GGVLLK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 GGVLLKR 7 1 M4PM71 M4PM71 SLC12A5 0 1 GGVLLK(1)R 69.432 0.019987 0 4051.7 3602.8 3630.1 3144.6 3488.4 4635.6 4416.4 4293.6 3871.6 3753.9 FALSE TRUE FALSE 3731.00367 3914.209978 3764.634699 3131.588478 3446.803108 3674.124306 4540.312298 5602.698875 3446.895166 3884.347746 0.960522568 1.007687837 0.969180657 0.806207035 0.887356986 0.945879346 1.168873797 1.442378294 0.887380686 1 11.92345665 -4.430141964 2.364910247 0.960746626 1.476059769 0.861680754 0.063560251 0.11499089 0.973013269 0.009475136 0.103333932 3.71E-05 4.430141964 0.515313143 GGVTGS(ph)PEASISGSK ddPTM_HeLa_Curcumin_4h_R1 5 GGVTGSPEASISGSK 15 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GGVT(0.002)GS(0.996)PEAS(0.002)ISGSK;GGVT(0.257)GS(0.731)PEAS(0.013)ISGSK;GGVT(0.005)GS(0.846)PEAS(0.148)IS(0.001)GSK;GGVT(0.003)GS(0.942)PEAS(0.054)ISGSK;GGVTGS(0.985)PEAS(0.014)ISGSK ;;;; 166.9 0.00021723 2516627700 28606.6 24698.8 27201.5 26459.7 30372.7 35212.6 31639.6 15459.2 27366.1 21904.3 TRUE FALSE FALSE 26342.35742 26833.65422 28209.61152 26350.21677 30010.52539 27909.10983 32527.32202 20172.63891 24364.1073 22665.47279 1.162224043 1.183900043 1.244607239 1.162570797 1.324063507 1.231349113 1.435104501 0.890016242 1.074943705 1 14.46820864 -8.471636078 0.520985541 0.992108668 1.231907205 0.195192551 0.133055048 0.840462663 0.471325248 0.092006803 0.03595429 3.38E-09 8.471636078 0.239798537 GGVTGS(ph)PEASISGSKGDLK ddPTM_HeLa_Curcumin_4h_R1 1 GGVTGSPEASISGSKGDLK 19 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GGVT(0.006)GS(0.994)PEASISGSKGDLK 102.15 0.00035939 142140000 2783.6 1936.9 1832.8 2241.1 1812.3 3291.7 2023.3 1413.7 3522.5 2218.2 TRUE FALSE FALSE 2563.275123 2104.317005 1900.72518 2231.826922 1790.689506 2608.964315 2080.068353 1844.730622 3136.090563 2295.282285 1.116758117 0.916800961 0.828100837 0.972354005 0.780160906 1.136663813 0.906236399 0.803705337 1.366320205 1 11.16445588 -7.239525016 20.31910487 1.05513574 0.909829932 0.34597023 0.139231301 65.18522876 60439.36316 0.016408987 0.020074091 5.76E-08 7.239525016 -0.145305808 GGVTGSPEASISGS(ph)KGDLK ddPTM_HeLa_Curcumin_4h_R1 3 GGVTGSPEASISGSKGDLK 19 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GGVTGS(0.001)PEAS(0.004)IS(0.296)GS(0.699)KGDLK;GGVTGSPEASIS(0.298)GS(0.702)KGDLK;GGVTGSPEAS(0.048)IS(0.086)GS(0.866)KGDLK ;; 164.69 9.62E-16 277959000 5961.5 5228.2 5412.3 5511.9 5918.5 7300.9 8895.5 1965.67 7665.9 5330.7 TRUE FALSE FALSE 5489.640984 5680.102312 5612.884599 5489.093218 5847.925753 5786.611042 9145.083789 2564.993734 6824.969949 5515.941428 0.995231921 1.029761172 1.017575091 0.995132615 1.06018634 1.049070429 1.657937073 0.465014679 1.237317335 1 12.42939142 -5.433610721 2.844268345 1.002390932 1.115301987 0 0.278900245 0.811487619 12.68875449 0.034525247 0.084194775 3.68E-06 5.433610721 0.112911055 GGVVGIK ddPTM_HeLa_Curcumin_4h_R1 2 GGVVGIK 7 0 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7;H3BR04;H3BMQ8;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 ; ; 103.41 0.018325 30097000 14012.8 11099.7 12634.5 11852.9 13894.9 16057.8 13391.6 12328.6 12938.9 11653.1 FALSE FALSE TRUE 12903.67209 12059.10861 13102.74568 11803.85584 13729.21239 12727.23127 13767.33225 16087.53339 11519.53504 12058.04436 1.070129758 1.000088261 1.086639367 0.97891959 1.138593621 1.055497135 1.141754985 1.334174341 0.955340244 1 13.55770832 -1.000000002 0.728041557 1.033567538 46.89303156 0.779180479 0.049505326 93.74386359 0.415511742 0.00692051 7037.502947 0.1 1.000000002 45.85946403 GHAVGDIPGVR ddPTM_HeLa_Curcumin_4h_R1 2 GHAVGDIPGVR 11 0 D6RD47;P62266 D6RD47 RPS23 40S ribosomal protein S23 0 0 ; ; 89.171 0.0068828 5254000 4606 3231.4 3486.22 3691.1 3581 4397.3 3394.4 3377.84 4239.7 4329.5 FALSE FALSE TRUE 4241.43024 3510.707817 3615.42238 3675.827206 3538.298914 3485.250412 3489.637728 4407.727866 3774.615517 4479.949803 0.94675843 0.783648918 0.807022967 0.820506338 0.789807714 0.777966398 0.778945721 0.983878851 0.842557547 1 12.12926685 -7.381880343 3.828819793 0.977505526 0.815456497 0.264853223 0.072106086 0.110736985 2.795957308 0.009980844 0.011322955 4.15E-08 7.381880343 -0.162049029 GHCPPAPAK(ac)PMHPENK ddPTM_HeLa_Curcumin_4h_R1 4 GHCPPAPAKPMHPENK 16 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;E9PNR0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 0 1 ;;; GHCPPAPAK(1)PMHPENK;GHCPPAPAK(1)PMHPENK;GHCPPAPAK(1)PMHPENK;GHCPPAPAK(1)PMHPENK 67.095 0.0066969 37550900 26413.7 21384.1 23201.1 23119.1 24211.6 27678.6 20808.9 13884.7 27325.7 23980.8 FALSE TRUE FALSE 24323.02777 23232.44632 24060.95318 23023.43929 23922.89248 21937.74636 21392.74173 18118.08111 24328.13908 24814.13102 0.980208727 0.936258711 0.969647221 0.927835808 0.964083428 0.884082797 0.862119319 0.730151747 0.980414711 1 14.59887431 -2.935785555 0.466379324 0.988926437 2.05E-16 0.921052388 0.02157678 2.322325518 0.134117243 0.00446506 1.672789403 0.00115935 2.935785555 -0.988926437 GHCPPAPAK(ac)PMHPENK(ac)LTNHGK ddPTM_HeLa_Curcumin_4h_R1 2 GHCPPAPAKPMHPENKLTNHGK 22 2 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;E9PNR0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 0 2 ; GHCPPAPAK(1)PMHPENK(1)LTNHGK;GHCPPAPAK(1)PMHPENK(1)LTNHGK 43.116 0.010591 27314000 8163.1 7017 7533.8 7405.7 8596.3 9692.2 6921.1 4757.5 9987.6 7680.6 FALSE TRUE FALSE 7516.982021 7623.518213 7813.009255 7375.057176 8493.794737 7681.928466 7115.287439 6208.039849 8891.985268 7947.500278 0.945829727 0.959234721 0.983077569 0.92797193 1.068737897 0.966584234 0.895286214 0.781131127 1.11884051 1 12.95628545 -4.420944798 2.249987362 0.976486227 0.764359817 0.56667012 0.057546169 0.172185126 1.269190119 0.005252077 0.062662223 3.79E-05 4.420944798 -0.21212641 GHLDAELDAYMAQTDPETND ddPTM_HeLa_Curcumin_4h_R1 1 GHLDAELDAYMAQTDPETND 20 0 X6R700;Q9Y3Y2-4;Q9Y3Y2;Q9Y3Y2-3 X6R700 CHTOP Chromatin target of PRMT1 protein 0 0 92.781 0.0051098 4914500 1304.8 1350.7 1225.4 1365.9 1718.6 1804.8 1292.3 975.11 1472.7 1378.8 FALSE FALSE TRUE 1201.523703 1467.448489 1270.814402 1360.248268 1698.106817 1430.464136 1328.55846 1272.41655 1311.148495 1426.713197 0.842162044 1.028551844 0.890728707 0.953413952 1.190222969 1.002629077 0.931202194 0.891851672 0.918999345 1 10.47847963 -5.985198343 24.99793367 0.930205482 1.007824094 0.11709042 0.087519014 401.8851531 678724.2049 0.014409056 0.026112117 1.03E-06 5.985198343 0.077618613 GHLENNPALEK ddPTM_HeLa_Curcumin_4h_R1 2 GHLENNPALEK 11 0 F8VWS0;P05388-2;Q8NHW5;P05388;G3V210;F8VU65;F8VS58;F8VQY6;F8VPE8;F8VRK7;F8VZS0;F8VWV4;F8VW21 F8VWS0 RPLP0;RPLP0P6 60S acidic ribosomal protein P0;60S acidic ribosomal protein P0-like 0 0 ; ; 126.66 0.00035027 21723000 16108.1 12040.7 12940.5 13373.4 12955 15319.2 13605.6 12784.1 14339.2 13539.5 FALSE FALSE TRUE 14833.12689 13081.44446 13420.08631 13318.06441 12800.52009 12141.82524 13987.33652 16681.91324 12766.22563 14009.99662 1.058753067 0.933722171 0.957893616 0.950611537 0.913670462 0.866654402 0.998382576 1.190715008 0.911222607 1 13.77416899 -7.262290639 24.97967315 1.027744503 0.966236997 0 0.089879516 134.5312878 3947704.56 0.014088553 0.016619304 5.47E-08 7.262290639 -0.061507506 GHLLYVALSPGQHR ddPTM_HeLa_Curcumin_4h_R1 2 GHLLYVALSPGQHR 14 0 O15067 O15067 PFAS Phosphoribosylformylglycinamidine synthase 0 0 ; ; 152.67 0.00017858 10552200 2895.7 2428.4 3209.8 2062.56 2983.3 6339.8 3630.1 3409.6 3090.4 2800.6 FALSE FALSE TRUE 2666.502289 2638.300075 3328.758012 2054.025673 2947.726096 5024.854016 3731.950836 4449.171344 2751.390852 2897.920642 0.920143309 0.91041143 1.148671211 0.708792934 1.017186618 1.73395156 1.287802979 1.535297855 0.949436231 1 11.50080237 -5.35788813 6.535598052 0.953713931 1.493908818 0.766599549 0.143754134 0.078662572 4.501078878 0.018559214 0.041840401 4.39E-06 5.35788813 0.540194887 GHLS(ph)EGLVTK ddPTM_HeLa_Curcumin_4h_R1 3 GHLSEGLVTK 10 0 Q16659 Q16659 MAPK6 Mitogen-activated protein kinase 6 1 0 GHLS(1)EGLVTK;GHLS(1)EGLVTK;GHLS(1)EGLVTK ;; 138.76 0.00021781 19267000 3537.08 2862.42 3427.34 3428.14 3360.95 5490.6 4626.11 2442.45 4084.94 3758.03 TRUE FALSE FALSE 3257.116386 3109.83483 3554.360235 3413.955265 3320.872866 4351.787668 4755.906196 3187.141761 3636.832302 3888.621263 0.837601856 0.799726849 0.914041249 0.877934629 0.853997508 1.11910813 1.223031474 0.819607142 0.935249811 1 11.92504301 -5.261090352 24.99580485 0.903954554 1.070827175 0.319094553 0.108329781 29.02882652 2078806.621 0.015943208 0.038060643 5.48E-06 5.261090352 0.166872621 GHPHSASS(ph)PSER ddPTM_HeLa_Curcumin_4h_R1 1 GHPHSASSPSER 12 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 0 GHPHSAS(0.177)S(0.739)PS(0.084)ER 126.09 0.0013906 481120 196.09 382.66 0 111.61 157.11 221.02 119.28 0 210.39 124.47 TRUE FALSE FALSE 180.5692696 415.7354253 0 111.1481874 155.2365659 175.1779606 122.6266758 0 187.3107434 128.7953232 1.401986229 3.227876718 0 0.862983101 1.205296605 1.36012672 0.952105035 0 1.454328765 1 7.008936398 GHQQLYWSHPR ddPTM_HeLa_Curcumin_4h_R1 1 GHQQLYWSHPR 11 0 A0A2R8Y851;P62273;P62273-2 A0A2R8Y851 RPS29 40S ribosomal protein S29 0 0 132.32 0.00072772 14899000 1829.1 1053.8 1435.3 1417.1 1697.9 2657 1804.3 1943.2 1714.7 1533.7 FALSE FALSE TRUE 1684.324805 1144.885776 1488.493481 1411.236416 1677.653651 2105.908249 1854.923802 2535.672735 1526.6017 1586.995961 1.06132898 0.721416944 0.937931486 0.889250162 1.057125344 1.3269777 1.168827047 1.597781467 0.961944288 1 10.63208274 -4.16561765 0.845095101 0.989826507 1.951128239 0.715811995 0.124194201 1.227749845 0.574393082 0.02076435 1.13805986 6.83E-05 4.16561765 0.961301732 GHTAS(ph)ESDEQQWPEEK ddPTM_HeLa_Curcumin_4h_R1 4 GHTASESDEQQWPEEK 16 0 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 GHT(0.023)AS(0.974)ES(0.003)DEQQWPEEK;GHT(0.001)AS(0.951)ES(0.048)DEQQWPEEK;GHT(0.1)AS(0.503)ES(0.397)DEQQWPEEK;GHT(0.084)AS(0.675)ES(0.242)DEQQWPEEK ;;; 279.19 2.29E-65 44636000 15117.6 12830.2 13459 14490.6 17160.4 16701.5 12848.3 13991.9 16320.4 14488.2 TRUE FALSE FALSE 13921.02601 13939.18532 13957.80238 14430.64174 16955.77344 13237.42064 13208.78872 18257.9659 14530.09295 14991.66387 0.928584454 0.929795748 0.931037575 0.962577727 1.131013447 0.882985421 0.881075565 1.217874551 0.969211495 1 13.87187289 -5.953644524 24.99855001 0.959139463 1.012281156 0.11415939 0.097290135 287.7016161 155150.1722 0.013855976 0.025116081 1.11E-06 5.953644524 0.053141693 GHTDTEGRPPS(ph)PPPTST(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 1 GHTDTEGRPPSPPPTSTPEK 20 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 2 0 GHT(0.002)DT(0.018)EGRPPS(0.979)PPPT(0.292)S(0.188)T(0.521)PEK 69.639 0.010382 40390000 3785.9 3044.1 3331.4 3357.2 3438.2 3877.9 2376.7 2102 4093.5 3266.3 TRUE FALSE FALSE 3486.24202 3307.21844 3454.864615 3343.308796 3397.201711 3073.579827 2443.383805 2742.890124 3644.453291 3379.803682 1.031492462 0.978523829 1.022208666 0.989202069 1.005147645 0.909395964 0.722936607 0.811553091 1.078303249 1 11.72272373 -4.984617375 3.02174057 1.010205832 0.767246394 0.891075891 0.034353099 0.041520927 0.770612114 0.003676013 0.012341242 1.04E-05 4.984617375 -0.242959438 GHTDTEGRPPS(ph)PPPTSTPEK ddPTM_HeLa_Curcumin_4h_R1 2 GHTDTEGRPPSPPPTSTPEK 20 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 0 GHT(0.003)DT(0.003)EGRPPS(0.993)PPPTSTPEK;GHT(0.017)DT(0.004)EGRPPS(0.979)PPPTSTPEK ; 79.236 0.0010753 95275000 6814.4 5743.9 5934.9 6629.9 6422.2 7545.4 6166.6 5231.9 7249.6 5834.5 TRUE FALSE FALSE 6275.033049 6240.377122 6154.852615 6602.46723 6345.619459 5980.398986 6339.618199 6827.082225 6454.337018 6037.248441 1.039386255 1.033645904 1.019479764 1.09362192 1.051078073 0.990583549 1.050084034 1.130826782 1.069085873 1 12.55967546 GHYEVT(ph)GSDDETGK ddPTM_HeLa_Curcumin_4h_R1 1 GHYEVTGSDDETGK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GHY(0.001)EVT(0.936)GS(0.06)DDET(0.003)GK 170.26 0.00058822 3302300 1009.3 841.68 1064 938.58 1118.9 989.28 827.8 531.01 710.21 708.41 TRUE FALSE FALSE 929.41284 914.4310687 1103.432776 934.6964047 1105.557848 784.0921765 851.0258401 692.9125045 632.3017399 733.0271948 1.267910449 1.247472229 1.505309467 1.275118319 1.508208503 1.069663148 1.160974444 0.945275304 0.862589743 1 9.517722912 -9.093771286 0.889483646 1.001881 1.255885191 0.331706873 0.170594661 0.66254142 0.958239604 0.10640673 0.032360628 8.06E-10 9.093771286 0.254004191 GHYEVT(ph)GSDDETGKLQGSGVSLASK ddPTM_HeLa_Curcumin_4h_R1 1 GHYEVTGSDDETGKLQGSGVSLASK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GHY(0.009)EVT(0.344)GS(0.308)DDET(0.338)GKLQGSGVS(0.001)LASK 65.901 0.00097216 9151400 868.01 642.02 760.66 983.46 1194.3 1093.9 908.09 411.18 954.73 927.01 TRUE FALSE FALSE 799.3060926 697.513348 788.8507287 979.3907031 1180.058753 867.0128092 933.5685614 536.5468892 849.9985076 959.2235285 0.833284494 0.727164553 0.822384674 1.021024479 1.230222902 0.903869415 0.973254443 0.55935543 0.886131837 1 9.905723236 -9.523741259 1.345752605 0.998687609 0.888843261 0.000675213 0.171833191 1.172775043 3.873059127 0.11351079 0.028629024 2.99E-10 9.523741259 -0.109844348 GHYEVTGS(ph)DDETGK ddPTM_HeLa_Curcumin_4h_R1 8 GHYEVTGSDDETGK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GHYEVTGS(0.994)DDET(0.005)GK;GHYEVT(0.135)GS(0.857)DDET(0.009)GK;GHYEVTGS(1)DDETGK;GHYEVT(0.257)GS(0.371)DDET(0.371)GK;GHYEVTGS(1)DDETGK;GHYEVTGS(1)DDETGK;GHYEVT(0.001)GS(0.999)DDETGK;GHYEVT(0.371)GS(0.616)DDET(0.014)GK ;;;;;;; 233.97 8.60E-21 745650800 39839.9 33711.8 40424.9 37287.2 47758.8 41454 35324.1 16334.1 33492.9 27983 TRUE FALSE FALSE 36686.52988 36625.69778 41923.08236 37132.91545 47189.3075 32855.97312 36315.19918 21314.2919 29818.81267 28955.40717 1.267001001 1.264900112 1.447849865 1.282417313 1.6297235 1.134709415 1.254176775 0.736107483 1.029818455 1 14.82154516 -9.020827741 0.843598776 1.002055892 1.26783651 0.15730173 0.215819168 0.831145943 1.089372044 0.133705695 0.042171634 9.53E-10 9.020827741 0.265780618 GHYEVTGS(ph)DDETGKLQGSGVSLASK ddPTM_HeLa_Curcumin_4h_R1 4 GHYEVTGSDDETGKLQGSGVSLASK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GHYEVT(0.025)GS(0.943)DDET(0.031)GKLQGS(0.001)GVSLASK;GHY(0.022)EVT(0.174)GS(0.792)DDET(0.013)GKLQGSGVSLASK;GHY(0.001)EVT(0.031)GS(0.73)DDET(0.239)GKLQGSGVSLASK;GHY(0.008)EVT(0.136)GS(0.588)DDET(0.257)GKLQGS(0.009)GVS(0.001)LASK ;;; 101.73 9.60E-07 657319000 14163.7 11059.7 12261.4 12211.1 14732.4 15916.8 12358.9 5792.17 12846.1 10507.2 TRUE FALSE FALSE 13042.6282 12015.65119 12715.81827 12160.5737 14556.72575 12615.47626 12705.65747 7558.175969 11436.91497 10872.32442 1.199617276 1.105159368 1.169558393 1.118488856 1.3388789 1.160329271 1.168623836 0.695175721 1.051929149 1 13.40837279 -4.258062958 24.34033795 1.127810697 0.695175482 0.700597438 0.087673021 118.1593842 851741.4901 0.014473481 0.139931832 5.52E-05 4.258062958 -0.432635215 GHYEVTGSDDET(ph)GKLQGSGVSLASK ddPTM_HeLa_Curcumin_4h_R1 3 GHYEVTGSDDETGKLQGSGVSLASK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GHY(0.005)EVT(0.02)GS(0.44)DDET(0.534)GKLQGSGVSLASK;GHY(0.008)EVT(0.131)GS(0.131)DDET(0.577)GKLQGS(0.145)GVS(0.009)LASK;GHY(0.004)EVT(0.062)GS(0.053)DDET(0.879)GKLQGS(0.001)GVS(0.001)LASK ;; 93.407 1.25E-05 98666400 5050.27 4143.73 4788.14 4373.83 5140.16 5456.22 4346.82 2035.19 5146.61 4128.25 TRUE FALSE FALSE 4650.5358 4501.895557 4965.59268 4355.73225 5078.866949 4324.538468 4468.78007 2655.710062 4582.039759 4271.70638 1.088683394 1.053886938 1.162437733 1.019670329 1.188955068 1.012367912 1.046134653 0.621697707 1.072648574 1 12.06059677 -4.259930182 5.494874262 1.058612093 0.605343132 0.834007109 0.059991599 0.046421819 5.344184627 0.008571228 0.078605696 5.50E-05 4.259930182 -0.453268961 STSLSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 STSLSSPR 8 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 0 STSLS(0.017)S(0.982)PR;STSLS(0.028)S(0.972)PR ; 93.598 0.0188 122904000 18630.1 15850.1 16579.5 16836.7 16448 18608.7 10057.9 5840.7 18964.8 17204.3 TRUE FALSE FALSE 17155.50793 17220.11202 17193.95085 16767.0342 16251.86834 14749.04586 10340.0976 7621.502543 16884.40889 17802.14814 0.963676282 0.967305287 0.965835736 0.941854548 0.912916139 0.828498097 0.580834263 0.428122633 0.948447836 1 14.11976372 -4.596471698 1.074898693 0.979020336 0.294520003 0.988580142 0.019572142 0.071579597 0.094020444 0.003019896 0.048432399 2.53E-05 4.596471698 -0.684500333 down LRLDT(ph)GSPEPETR ddPTM_HeLa_Curcumin_4h_R1 1 LRLDTGSPEPETR 13 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 0 LRLDT(0.833)GS(0.167)PEPETR 169.4 0.0018476 39980000 1466.9 1172.1 1208.6 1342.9 1249.2 1184.7 685.43 164.33 1571.1 1382 TRUE FALSE FALSE 1350.793317 1273.411101 1253.391779 1337.343436 1234.304106 938.9798657 704.6613211 214.4334605 1398.754261 1430.024397 0.944594596 0.890482081 0.876482794 0.935189245 0.863134999 0.656618074 0.492761748 0.149950911 0.978133145 1 10.48182405 -4.596163219 0.926257096 0.96134347 1.75E-22 0.972368661 0.042766928 0.159847843 0.142834659 0.007506104 0.136554155 2.53E-05 4.596163219 -0.96134347 down GHYTEGAELVDSVLDVVR ddPTM_HeLa_Curcumin_4h_R1 3 GHYTEGAELVDSVLDVVR 18 0 Q5JP53;P07437;Q5ST81;P68371;Q9BVA1;Q13885;A0A0B4J269;Q13509;Q13509-2;G3V2A3 Q5JP53;P68371;Q9BVA1;A0A0B4J269 TUBB;TUBB4B;TUBB2B;TUBB2A;TUBB3 Tubulin beta chain;Tubulin beta-4B chain;Tubulin beta-2B chain;Tubulin beta-2A chain;Tubulin beta-3 chain 0 0 ;; ;; 180.1 5.88E-07 39114210 4083.65 3345.53 4012.05 3159.41 4940.06 7173.94 4735.82 4738.5 4309.55 2995.14 FALSE FALSE TRUE 3760.424793 3634.702706 4160.740102 3146.337199 4881.153011 5685.983977 4868.694363 6183.246837 3836.803147 3099.220892 1.2133452 1.172779493 1.342511633 1.015202629 1.574961315 1.834649473 1.570941386 1.995097172 1.237989572 1 11.59768987 -1 0.239574559 1.014198479 6.865505589 0.734872774 0.164994971 15.26692257 0.188213981 0.092144897 35.89516074 0.1 1 5.851307111 GHYTEGAELVDSVLDVVRK ddPTM_HeLa_Curcumin_4h_R1 2 GHYTEGAELVDSVLDVVRK 19 1 Q5JP53;P07437;Q5ST81;P68371;Q9BVA1;Q13885;A0A0B4J269;Q13509;Q13509-2;G3V2A3 Q5JP53;P68371;Q9BVA1;A0A0B4J269 TUBB;TUBB4B;TUBB2B;TUBB2A;TUBB3 Tubulin beta chain;Tubulin beta-4B chain;Tubulin beta-2B chain;Tubulin beta-2A chain;Tubulin beta-3 chain 0 0 ; ; 166.3 2.48E-06 51723000 15193.6 11792.3 10756.1 10964 13281.3 30009 14785.7 14318.1 22615 15454.7 FALSE FALSE TRUE 13991.01053 12811.57387 11154.73053 10918.63387 13122.92917 23784.79513 15200.54695 18683.62278 20134.19108 15991.74967 0.874889291 0.801136469 0.697530336 0.682766683 0.820606215 1.487316623 0.950524318 1.168328867 1.259036159 1 13.96504017 -5.304304811 24.99927726 0.883376129 1.176903865 0.362139633 0.196966313 349.450929 203800.5107 0.024251045 0.054227283 4.96E-06 5.304304811 0.293527736 GHYTIGK ddPTM_HeLa_Curcumin_4h_R1 3 GHYTIGK 7 0 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;A0A1W2PQM2;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;P68363;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2 Q9BQE3;P68363;P68366-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 0 ;; ;; 114.72 0.011733 37186000 27954.3 34013.4 22765.1 16090.1 35159 53189 28020.8 26705.2 27956.4 25017.9 FALSE FALSE TRUE 25741.68766 36953.36674 23608.79463 16023.52343 34739.75189 42157.00184 28806.98823 34847.49254 24889.65286 25887.27016 0.99437629 1.427472518 0.911984712 0.618973083 1.341962736 1.628483868 1.112785862 1.346124652 0.961463017 1 14.65995522 -5.57198158 24.99864069 1.001488911 1.362119059 0.412282318 0.21698372 82.722918 42114.61288 0.030634877 0.061269765 2.68E-06 5.57198158 0.360630147 IQQHVGEEAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 IQQHVGEEASPR 12 0 Q8TER5;Q8TER5-4;Q8TER5-3;Q8TER5-2 Q8TER5 ARHGEF40 Rho guanine nucleotide exchange factor 40 1 0 IQQHVGEEAS(1)PR 139.74 0.00070656 0 1130.7 927.93 952.8 1058.1 974.69 921.62 512.11 172.11 956.75 1103.7 TRUE FALSE FALSE 1041.203902 1008.136134 988.1116062 1053.721863 963.0674583 730.4656232 526.4784283 224.5855467 851.7969187 1142.053493 0.911694512 0.882739855 0.865206063 0.922655435 0.843277013 0.639607188 0.460992792 0.196650637 0.745846779 1 10.15741451 -4.595703724 0.850661822 0.948820166 1.67E-16 0.901258243 0.074352518 0.188976531 0.136017828 0.007724107 0.149617844 2.54E-05 4.595703724 -0.948820166 down GIASTSDPPTANIKPTPVVS(ph)TPSK ddPTM_HeLa_Curcumin_4h_R1 1 GIASTSDPPTANIKPTPVVSTPSK 24 1 P12270 P12270 TPR Nucleoprotein TPR 1 0 GIASTSDPPTANIKPT(0.011)PVVS(0.486)T(0.486)PS(0.016)K 102.27 3.13E-06 82594000 8289.3 7004.1 7876.5 8315.8 9621.3 12702 15780 4612.4 8680.8 7359.3 TRUE FALSE FALSE 7633.193158 7609.503194 8168.410019 8281.391423 9506.572281 10067.46202 16222.74433 6018.699527 7728.537958 7615.035127 1.002384497 0.999273551 1.072668725 1.087505348 1.248395066 1.322050634 2.130357124 0.790370553 1.014905096 1 12.89463498 -5.534109394 1.812270006 1.008233517 1.488513164 0.242695027 0.304213514 0.290508818 1.886022736 0.040567156 0.107657318 2.92E-06 5.534109394 0.480279647 GIASTSDPPTANIKPTPVVST(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 GIASTSDPPTANIKPTPVVSTPSK 24 1 P12270 P12270 TPR Nucleoprotein TPR 1 0 GIASTSDPPT(0.001)ANIKPT(0.014)PVVS(0.395)T(0.464)PS(0.126)K 74.905 0.00048736 83184000 3922.2 3467.5 3366.4 3914.3 5014.8 5175.2 6209 1718.8 3634.7 2911.5 TRUE FALSE FALSE 3611.753731 3767.215249 3491.161745 3898.103664 4955.001785 4101.805183 6383.207829 2242.854208 3235.982504 3012.674408 1.198852993 1.250455489 1.158824776 1.29390141 1.64471865 1.361516257 2.118784497 0.744472818 1.074122877 1 11.55682905 -6.724473772 0.584762132 1.054888444 1.509225528 0.167881969 0.325457166 0.821147347 0.586968986 0.080994199 0.147853813 1.89E-07 6.724473772 0.454337084 GIAYIEFK ddPTM_HeLa_Curcumin_4h_R1 2 GIAYIEFK 8 0 P19338;H7BY16 P19338 NCL Nucleolin 0 0 ; ; 136.11 0.0010706 3807500 4912.1 2201.53 4550 3608.6 3289.2 6758.1 5504.5 4366.8 4044.8 4037.3 FALSE FALSE TRUE 4523.302102 2391.820443 4718.627003 3593.668569 3249.978438 5356.393881 5658.941455 5698.217218 3601.09556 4177.595874 1.082752434 0.572535141 1.129507771 0.86022408 0.777954244 1.282171383 1.354592839 1.363994362 0.862001895 1 12.02845722 -5.106722176 6.159475551 0.982500252 1.349687169 0.564056905 0.164921735 0.144634142 7.097241231 0.023088525 0.060037589 7.82E-06 5.106722176 0.367186917 GIDPFSLDALSK ddPTM_HeLa_Curcumin_4h_R1 1 GIDPFSLDALSK 12 0 P40227;P40227-2 P40227 CCT6A T-complex protein 1 subunit zeta 0 0 99.53 0.009987 401070 207.15 0 64.637 0 175.1 167.24 154.51 0 68.978 222.67 FALSE FALSE TRUE 190.7538589 0 67.03250408 0 173.0120469 132.5525388 158.8451348 0 61.41128597 230.4077659 0.82789683 0 0.290929882 0 0.750895032 0.575295448 0.689408771 0 0.266533056 1 7.848045534 -7.421525701 6.322124499 0.925090604 0.355409575 0.105669542 0.337591874 0.148621887 7.825731995 0.046380052 0.052715465 3.79E-08 7.421525701 -0.569681028 GIDRMLRDQKR ddPTM_HeLa_Curcumin_4h_R1 1 GIDRMLRDQKR 11 3 P38405-2 P38405-2 0 0 57.785 0.014103 11300000 4307.9 3666.3 4724.7 4052.7 3722.2 4477.1 3803.8 4287.4 5277.7 4810.7 FALSE FALSE TRUE 3966.925169 3983.198635 4899.801538 4035.931001 3677.815196 3548.498993 3910.524391 5594.608523 4698.749514 4977.871467 0.796911932 0.800181094 0.984316604 0.81077445 0.738832897 0.712854684 0.785581632 1.123895737 0.943927449 1 12.28131326 -9.347073784 0.951393446 1.005111524 0.833778048 0.14858642 0.117677102 0.742851702 1.14603335 0.091049618 0.021182665 4.50E-10 9.347073784 -0.171333477 GIEPTGNMVK ddPTM_HeLa_Curcumin_4h_R1 1 GIEPTGNMVK 10 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 105.4 0.0067474 3143500 1745.9 1106.8 1237.8 1412.5 1597 1598.7 1504.9 1434.9 1600.6 1447.8 FALSE FALSE TRUE 1607.710173 1202.46686 1283.673957 1406.655449 1577.956818 1267.111599 1547.123444 1872.394405 1425.018185 1498.110942 1.073158287 0.802655415 0.856861745 0.93895279 1.053297705 0.845806251 1.032716203 1.249836946 0.95121005 1 10.54892875 -4.288718142 4.198634078 0.989035783 1.264631284 0.437670254 0.0940131 0.166649824 6.307340314 0.014484859 0.12954026 5.14E-05 4.288718142 0.275595502 GIETRRR ddPTM_HeLa_Curcumin_4h_R1 1 GIETRRR 7 2 Q5TCS8-1 Q5TCS8-1 AK9 Adenylate kinase 9 0 0 38.806 0.0192 1324900 618.94 408.27 386.54 602.84 422.65 423.81 356.01 562.25 557.43 419.73 FALSE FALSE TRUE 569.9502459 443.5590396 400.8655124 600.3456078 417.6101748 335.9070287 365.9986824 733.6774367 496.2813236 434.3155863 1.31229517 1.021282804 0.922982101 1.382279676 0.961536238 0.773416933 0.84270216 1.689272639 1.14267445 1 8.762599917 GIFPVLCK ddPTM_HeLa_Curcumin_4h_R1 2 GIFPVLCK 8 0 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BR70 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 122.15 0.0024923 3164800 4206.6 3830.9 3968.9 2894 4421.3 5671.2 4109.7 3398.6 3166.2 2883.4 FALSE FALSE TRUE 3873.643171 4162.025926 4115.990925 2882.025395 4368.578885 4494.929192 4225.007121 4434.817495 2818.875781 2983.597935 1.298312727 1.394968765 1.379539407 0.965956358 1.464198253 1.506546555 1.416077908 1.48639917 0.944790767 1 11.54283742 -12.54844122 0.113127061 1.57E-15 1.605401102 0.587832854 0.137529085 45.5135212 0.473736607 11.27407436 0.880391524 2.83E-13 12.54844122 1.605401102 GIFPVLCKDPVQEAWAEDVDLR ddPTM_HeLa_Curcumin_4h_R1 2 GIFPVLCKDPVQEAWAEDVDLR 22 1 P14618;P14618-3;B4DNK4;P14618-2;H3BR70 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 221.81 3.04E-23 1044900000 3984.1 2882.86 3407.42 2740.41 2801.42 6477.6 4049.5 4272.8 3662 3574.7 FALSE FALSE TRUE 3668.754281 3132.041573 3533.701983 2729.07091 2768.014896 5134.072742 4163.118071 5575.55705 3260.287762 3698.920559 0.991844573 0.846744752 0.9553333 0.737801979 0.748330453 1.387992162 1.125495399 1.507347066 0.881416 1 11.8528886 -5.248708457 24.87083525 0.947263726 1.318799956 0.69525662 0.134322978 374.8235696 732244.9105 0.019391099 0.049074877 5.64E-06 5.248708457 0.37153623 AAS(ph)YTEEDENHTAK ddPTM_HeLa_Curcumin_4h_R1 1 AASYTEEDENHTAK 14 0 Q14126 Q14126 DSG2 Desmoglein-2 1 0 AAS(0.967)YT(0.033)EEDENHTAK 109.1 0.0014686 23167000 5438.3 5246.4 5760.8 7677.2 5909.1 7989.1 3392.2 1654.4 7811.5 5464.3 TRUE FALSE FALSE 5007.852817 5699.875438 5974.300316 7645.433781 5838.637842 6332.070604 3487.376002 2158.818944 6954.597993 5654.184018 0.885689748 1.008080993 1.056615826 1.35217279 1.032622536 1.119891143 0.616777946 0.381809106 1.229991449 1 12.46510312 -4.595542156 4.032722433 1.00132063 0.424142504 0.708391946 0.145672838 0.088417354 2.723611106 0.020293679 0.091093948 2.54E-05 4.595542156 -0.577178126 down GIGTDEFTLNR ddPTM_HeLa_Curcumin_4h_R1 1 GIGTDEFTLNR 11 0 P12429;D6RA82 P12429 ANXA3 Annexin A3;Annexin 0 0 128.86 7.41E-11 0 6735.6 5130.7 5497.2 5490.6 5462.7 5819.9 5277.7 4763.3 5840.1 5257 FALSE FALSE TRUE 6202.470153 5574.174846 5700.931068 5467.881352 5397.56087 4612.787136 5425.778058 6215.608242 5199.455641 5439.680359 1.140226952 1.024724704 1.048026849 1.005184311 0.992256992 0.847988638 0.99744428 1.142642183 0.95583845 1 12.40930616 -6.317802025 1.901841621 1.064831511 0.98592801 0 0.081851594 0.50018402 3.532928281 0.01361126 0.023434674 4.81E-07 6.317802025 -0.078903502 GIGTPPNTT(ph)PIKNGSPEIK ddPTM_HeLa_Curcumin_4h_R1 1 GIGTPPNTTPIKNGSPEIK 19 1 O96028-5;O96028-3;O96028;D6RIS1;D6R9V2;O96028-7;O96028-6 O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 0 GIGT(0.001)PPNT(0.163)T(0.674)PIKNGS(0.163)PEIK 88.427 0.0019587 60054000 2346.8 1736.4 1690 1994.5 1900.9 2644.5 1326 1034 2287.9 2011.6 TRUE FALSE FALSE 2161.048304 1886.486679 1752.632887 1986.247287 1878.233009 2096.00089 1363.203991 1349.26184 2036.923094 2081.50295 1.038215345 0.906309875 0.842003556 0.954237075 0.90234463 1.006965131 0.654913312 0.648215195 0.978582852 1 11.02340989 -3.531153945 0.483983844 1.006966219 1.57E-14 0.638709566 0.079757073 3.345619687 0.317107621 0.016978218 2.24610845 0.000294338 3.531153945 -1.006966219 GIGTPPNTTPIKNGS(ph)PEIK ddPTM_HeLa_Curcumin_4h_R1 1 GIGTPPNTTPIKNGSPEIK 19 1 O96028-5;O96028-3;O96028;D6RIS1;D6R9V2;O96028-7;O96028-6 O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 0 GIGTPPNT(0.025)T(0.017)PIKNGS(0.958)PEIK 63.536 0.0074332 58816000 2877.4 2034.4 2606.1 2593.4 2346.9 2953.5 1665.6 1922.4 3961.8 3059.6 TRUE FALSE FALSE 2649.650754 2210.244471 2702.684359 2582.669198 2318.91475 2340.910807 1712.332253 2508.53091 3527.200452 3165.920872 0.836928925 0.698136359 0.853680325 0.815771872 0.732461373 0.739409133 0.540863882 0.792354266 1.114115164 1 11.62840948 -9.705670945 0.106541479 1.419053455 0.490385874 0.687596042 0.084295002 14.447161 0.340620367 2.405888401 0.815310328 1.97E-10 9.705670945 -0.92866758 GIITDS(ph)FGR ddPTM_HeLa_Curcumin_4h_R1 2 GIITDSFGR 9 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;C9JUH3;Q9BSQ5-3 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 0 GIITDS(1)FGR;GIITDS(1)FGR ; 114.89 0.0075697 44915500 5661.3 5382.7 5391 4954.6 5166.2 7266.2 5446.4 5181.5 5938.8 5742.4 TRUE FALSE FALSE 5213.202131 5847.956603 5590.795202 4934.099178 5104.596439 5759.108213 5599.211326 6761.315497 5287.328498 5941.947973 0.877355735 0.984181725 0.940902752 0.83038411 0.859077943 0.969228987 0.942319144 1.137895439 0.88983083 1 12.53672026 -4.245933838 3.854439438 0.931916321 1.161445296 0.58513631 0.054074886 0.187569979 5.304695102 0.008736207 0.123049784 5.68E-05 4.245933838 0.229528975 GIK(ac)VQSVDK ddPTM_HeLa_Curcumin_4h_R1 1 GIKVQSVDK 9 1 A0A494C1K8;A0A494C139;A0A0A0MTC7;A0A0A0MQS9;Q16363-2;Q16363 A0A494C1K8 LAMA4 Laminin subunit alpha-4 0 1 GIK(1)VQSVDK 101.25 0.0082411 1256300 1032.7 904.33 1241.6 1247.7 1121.1 356.44 438.37 523.97 1105.5 875.4 FALSE TRUE FALSE 950.9607053 982.4962556 1287.614788 1242.537348 1107.731615 282.5103261 450.6694824 683.7260409 984.2294158 905.8200848 1.049833981 1.084648345 1.421490658 1.371726426 1.222904673 0.311883486 0.497526484 0.754814397 1.086561705 1 9.823080719 -5.266394612 24.96910079 1.097638224 0.519019951 0.736634553 0.175149346 187.904509 946841.1308 0.028597213 0.065864851 5.42E-06 5.266394612 -0.578618272 GILAADES(ph)TGSIAK ddPTM_HeLa_Curcumin_4h_R1 3 GILAADESTGSIAK 14 0 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 0 GILAADES(0.493)T(0.493)GS(0.014)IAK;GILAADES(0.795)T(0.205)GSIAK;GILAADES(0.594)T(0.405)GS(0.001)IAK ;; 212.83 6.49E-11 50737400 10253.5 9409.1 10003.1 10095.5 10572.7 13245.7 10018.9 8539.2 11450.1 9855.4 TRUE FALSE FALSE 9441.924656 10222.38068 10373.82369 10053.7275 10446.62746 10498.39251 10300.00337 11142.76277 10194.05268 10197.87442 0.925871831 1.002403075 1.017253524 0.985865003 1.024392636 1.029468699 1.010014729 1.092655422 0.999625242 1 13.31598086 -4.82911318 0.505365938 0.967891404 1.10075897 0.452372868 0.029022125 1.750998574 0.427712877 0.007805277 0.123577891 1.48E-05 4.82911318 0.132867567 GILAADESTGS(ph)IAK ddPTM_HeLa_Curcumin_4h_R1 5 GILAADESTGSIAK 14 0 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 0 GILAADESTGS(1)IAK;GILAADES(0.008)T(0.283)GS(0.71)IAK;GILAADES(0.005)T(0.047)GS(0.949)IAK;GILAADES(0.007)T(0.054)GS(0.939)IAK;GILAADES(0.264)T(0.264)GS(0.471)IAK ;;;; 225.86 2.88E-20 53415000 14726.7 15011.29 12978.2 16342.4 14047.09 13327.9 11262.5 9398.42 17259.8 14301.1 TRUE FALSE FALSE 13561.06616 16308.79902 13459.18351 16274.77948 13879.58763 10563.5433 11578.49544 12263.95499 15366.44312 14798.06216 0.916408244 1.102090182 0.90952338 1.099791263 0.937932783 0.713846393 0.782433221 0.828754121 1.038409148 1 13.85312064 -5.375819438 5.430277481 0.977276108 0.776907671 0.674769746 0.070869235 0.10622888 4.363480141 0.009779972 0.022223989 4.21E-06 5.375819438 -0.200368437 GILAADESTGS(ph)IAKR ddPTM_HeLa_Curcumin_4h_R1 2 GILAADESTGSIAKR 15 1 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 0 GILAADESTGS(1)IAKR;GILAADES(0.097)T(0.097)GS(0.806)IAKR ; 228.03 1.41E-20 31883000 6167.1 5078.8 4993.6 4914.6 5088.2 6865.9 5783.5 4965.4 6651.8 6044 TRUE FALSE FALSE 5678.967528 5517.788841 5178.667209 4894.264687 5027.526538 5441.834945 5945.769445 6479.327602 5922.114182 6254.02855 0.908049505 0.882277527 0.828053017 0.782577925 0.803886087 0.870132732 0.950710314 1.036024628 0.94692791 1 12.61057009 -8.411722409 0.828244264 0.990288839 0.875115763 0.201225815 0.070793216 0.543384466 0.780079057 0.03026084 0.016718029 3.88E-09 8.411722409 -0.115173076 GILAADESTGSIAK ddPTM_HeLa_Curcumin_4h_R1 2 GILAADESTGSIAK 14 0 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 ; ; 277.1 1.39E-93 67440000 10904.4 8769.8 9710.1 9676.4 10775.5 12314.5 10101.5 8617.6 10349.4 8208.4 FALSE FALSE TRUE 10041.30523 9527.822435 10069.96485 9636.361621 10647.0092 9760.333887 10384.9209 11245.06657 9214.096713 8493.641289 1.182214423 1.121759456 1.185588666 1.134538332 1.253527061 1.149134223 1.22267006 1.323939426 1.084822916 1 13.05216747 -13.52287875 0.123176712 0.3225189 1.299679013 0.628010301 0.052409966 32.10713245 0.284015756 5.391247327 0.202372651 3.00E-14 13.52287875 0.977160113 GILAADESTGSIAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GILAADESTGSIAKR 15 1 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 1 ; GILAADESTGSIAK(1)R;GILAADESTGSIAK(1)R 290.28 1.93E-112 94556000 7977.1 6976.9 6881.2 6155.4 8010.4 9864.7 8469.2 8530.9 10116.8 6703 FALSE TRUE FALSE 7345.704118 7579.952148 7136.223325 6129.930586 7914.881212 7818.650022 8706.822958 11131.93214 9007.012351 6935.928751 1.0590801 1.092853231 1.02887783 0.883793765 1.141142231 1.127267927 1.255321857 1.604966334 1.298602202 1 12.75987336 -3.781423803 0.936928001 1.027030734 2.53169237 0.692408881 0.105277414 0.972350511 0.348747797 0.009442831 1.842362046 0.000165415 3.781423803 1.504661636 GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK ddPTM_HeLa_Curcumin_4h_R1 4 GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK 38 0 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 ;;; ;;; 63.261 3.46E-05 23321600 3102.48 4431.98 5967.24 5147.65 6584.6 3947.82 2860.85 2319.85 1678.04 0 FALSE FALSE TRUE 2856.915434 4815.060603 6188.391164 5126.350388 6506.082946 3128.997631 2941.117751 3027.161586 1493.96321 0 0 GILHLS(ph)PDVYQEMEASR ddPTM_HeLa_Curcumin_4h_R1 1 GILHLSPDVYQEMEASR 17 0 H0YBY0;E7EPX0;E7EVJ4;Q9NUL3-4;Q9NUL3-6;Q9NUL3-8;Q9NUL3-3;Q9NUL3-7;Q9NUL3-2;Q9NUL3;E5RJ67;E5RJN7 H0YBY0 STAU2 Double-stranded RNA-binding protein Staufen homolog 2 1 0 GILHLS(1)PDVYQEMEASR 62.237 0.018737 20888000 5017.6 3979.3 3705 4391.8 4261 7015.7 5305.5 3034.5 5127.3 4042.3 TRUE FALSE FALSE 4620.451665 4323.252961 3842.310559 4373.627895 4210.190358 5560.564737 5454.358051 3959.705081 4564.848018 4182.769624 1.104639289 1.0335862 0.918604395 1.04562964 1.00655564 1.3293978 1.304006326 0.946670612 1.09134579 1 12.03024283 -5.283788896 24.94085823 1.036431824 1.204423069 0.326657263 0.10762691 620.9350992 692929.3547 0.014952682 0.033457707 5.20E-06 5.283788896 0.167991245 GILLFGPPGTGK ddPTM_HeLa_Curcumin_4h_R1 2 GILLFGPPGTGK 12 0 I3L4J1;Q9UN37;Q6PIW4-2;Q6PIW4;O75351 I3L4J1;O75351 VPS4A;FIGNL1;VPS4B Vacuolar protein sorting-associated protein 4A;Fidgetin-like protein 1;Vacuolar protein sorting-associated protein 4B 0 0 ; ; 102.06 0.003346 345230 375.65 461.14 487.55 328.01 491.23 644.99 479.21 376.01 600.1 431.7 FALSE FALSE TRUE 345.9169061 500.9988868 505.6190319 326.6527815 485.3724031 511.2118035 492.6553429 490.6537181 534.2705314 446.7015429 0.77438037 1.121551727 1.131894528 0.7312551 1.086569793 1.144414681 1.102873609 1.09839271 1.196034668 1 8.803167427 -5.566161383 0.785894318 0.911813464 1.142199659 0 0.159086654 0.890326861 0.933003585 0.026379353 0.122414023 2.72E-06 5.566161383 0.230386195 GILLQLFGGTRK ddPTM_HeLa_Curcumin_4h_R1 1 GILLQLFGGTRK 12 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;A0A3B3IU45;E5RG31;A0A3B3IRR8 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 0 0 141.89 9.35E-17 0 959.99 637.09 775.78 561.08 763.41 2171.8 1506.2 1092.6 965.41 997.24 FALSE FALSE TRUE 884.0057785 692.1572208 804.5310892 558.7583996 754.3068343 1721.344199 1548.459918 1425.72871 859.5069383 1031.894016 0.856682726 0.670763867 0.779664459 0.541488167 0.730992547 1.668140499 1.500599766 1.381661962 0.832941102 1 10.01107909 -5.262846394 24.99994792 0.857325624 1.515180663 0.835451013 0.147965385 46.58841637 827796.0217 0.025473764 0.060006087 5.46E-06 5.262846394 0.65785504 GILSLPHQAS(ph)PVSR ddPTM_HeLa_Curcumin_4h_R1 2 GILSLPHQASPVSR 14 0 O75925;O75925-2 O75925 PIAS1 E3 SUMO-protein ligase PIAS1 1 0 GILS(0.001)LPHQAS(0.966)PVS(0.033)R;GILSLPHQAS(0.995)PVS(0.005)R ; 120.59 0.00082242 129298000 8557.2 6660.9 7170.9 6689.5 7573.8 9948.4 7113.6 3321.1 8401.6 6958.5 TRUE FALSE FALSE 7879.88859 7236.638516 7436.659862 6661.820621 7483.487382 7884.989698 7313.188471 4333.688102 7479.9655 7200.307357 1.094382253 1.005045779 1.032825336 0.925213368 1.03932888 1.09509071 1.015677263 0.601875432 1.038839751 1 12.81384278 -4.262843593 5.337472794 1.036230847 0.58475993 0.88325642 0.04636611 0.039600755 4.041762269 0.007253177 0.065212668 5.46E-05 4.262843593 -0.451470917 GINGVSPK ddPTM_HeLa_Curcumin_4h_R1 2 GINGVSPK 8 0 P18124;A8MUD9;C9JZ88;C9JIJ5 P18124 RPL7 60S ribosomal protein L7 0 0 ; ; 114.5 0.0040038 13276000 8691.5 7010.5 7522 7179.1 8536.3 8574.5 6690.2 7560.1 8412.6 6714.4 FALSE FALSE TRUE 8003.558604 7616.456382 7800.771937 7149.394786 8434.510198 6796.052045 6877.909006 9865.139688 7489.758827 6947.7249 1.151968266 1.096251865 1.122780773 1.029026752 1.213995994 0.978169421 0.989951258 1.41990937 1.078016032 1 12.76232492 -9.401675028 1.034096632 0.997408182 1.117581907 0.056542275 0.123017891 0.944386883 1.743234137 0.085878709 0.020044084 3.97E-10 9.401675028 0.120173725 GINSSNVENQLQATQAAR ddPTM_HeLa_Curcumin_4h_R1 1 GINSSNVENQLQATQAAR 18 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 0 0 353.45 6.92E-231 1755300 80.247 209.38 227.72 212.2 60.218 212.81 309.8 155.99 197.62 376.38 FALSE FALSE TRUE 73.89536527 227.4778742 236.1595035 211.3219726 59.49993968 168.6708071 318.4921542 203.5506329 175.9415804 389.459177 0.189738411 0.584086568 0.606378069 0.542603654 0.152775806 0.433089826 0.817780587 0.522649471 0.451758723 1 8.605328303 -9.526274179 1.277187915 1.000639804 0.454043612 0 0.248816364 0.306904351 0.894705576 0.145621445 0.034702741 2.98E-10 9.526274179 -0.546596192 GIPGLDVEDDEEGGGGAP ddPTM_HeLa_Curcumin_4h_R1 2 GIPGLDVEDDEEGGGGAP 18 0 Q9ULX6;Q9ULX6-2 Q9ULX6 AKAP8L A-kinase anchor protein 8-like 0 0 ; ; 194.54 3.79E-08 13471900 7626.7 6385.6 6986.2 6648.3 6882.9 8075.4 5899.1 4835.4 7793.7 6724.7 FALSE FALSE TRUE 7023.038647 6937.54281 7245.114718 6620.791096 6800.825913 6400.471011 6064.612869 6309.691201 6938.750609 6958.382824 1.009291789 0.997005049 1.041206686 0.951484169 0.977357252 0.919821627 0.871554932 0.90677552 0.997178624 1 12.76453634 -5.350672027 1.229984073 1.005391298 0.88431129 0.826144531 0.021057733 0.130400304 0.359949631 0.002978046 0.011949016 4.46E-06 5.350672027 -0.121080008 GIPHLVTHDAR ddPTM_HeLa_Curcumin_4h_R1 4 GIPHLVTHDAR 11 0 C9JEH7;Q8TD47;P62701;P22090 C9JEH7 RPS4Y1;RPS4Y2;RPS4X "40S ribosomal protein S4, Y isoform 2;40S ribosomal protein S4, X isoform;40S ribosomal protein S4, Y isoform 1" 0 0 ;;; ;;; 153.1 7.91E-05 46084900 22480.1 16240.9 18438.5 16850.3 19615.3 25142.9 18816.5 18154.1 19713.2 19126.6 FALSE FALSE TRUE 20700.77636 17644.69103 19121.84703 16780.57792 19381.40036 19927.97912 19344.44035 23689.20152 17550.71128 19791.24793 1.045956093 0.891540094 0.966176923 0.847878718 0.979291474 1.00690867 0.977423982 1.196953401 0.886791543 1 14.27257496 -4.258877029 24.34563905 0.992111084 1.196953508 0.466696549 0.068002081 116.0092991 1102138.343 0.009269338 0.084452971 5.51E-05 4.258877029 0.204842424 GIPLATGDTS(ph)PEPELLPGAPLPPPK ddPTM_HeLa_Curcumin_4h_R1 2 GIPLATGDTSPEPELLPGAPLPPPK 25 0 K7ENA8;O75821;K7EL60;K7ER90;K7EL20 K7ENA8 EIF3G Eukaryotic translation initiation factor 3 subunit G 1 0 GIPLAT(0.007)GDT(0.186)S(0.807)PEPELLPGAPLPPPK;GIPLAT(0.01)GDT(0.174)S(0.816)PEPELLPGAPLPPPK ; 122.51 1.69E-08 219480000 10432.5 9130.6 9994.4 9504.2 10711.4 10783.3 10292.2 12622.5 9522.6 8547.1 TRUE FALSE FALSE 9606.756617 9919.808379 10364.80126 9464.874139 10583.67355 8546.722027 10580.97143 16471.04214 8477.994604 8844.111089 1.086232016 1.12162865 1.171943811 1.070189423 1.196691611 0.966374341 1.196386084 1.862373955 0.95860336 1 13.11050143 -4.273166459 3.289790476 1.065933911 1.961600924 0.904770621 0.076508621 0.062117047 1.091454228 0.010282517 0.138536765 5.33E-05 4.273166459 0.895667013 S(ph)LLSAEEAAK ddPTM_HeLa_Curcumin_4h_R1 1 SLLSAEEAAK 10 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 1 0 S(0.789)LLS(0.211)AEEAAK 100.82 0.012033 2014300 1316.4 1258.6 1220.4 1192.4 1439.7 1646.3 1411.5 7440.2 1340.1 1029.7 TRUE FALSE FALSE 1212.205551 1367.387776 1265.629098 1187.466165 1422.532518 1304.838822 1451.102891 9708.68273 1193.094383 1065.481998 1.137706271 1.283351364 1.187846533 1.114487309 1.335107041 1.224646521 1.361921547 9.112010099 1.11976963 1 10.0572905 -4.261106784 5.754323808 1.127115837 9.363284665 0.998275134 0.098723837 0.004938908 0.70089002 0.018001765 0.158692403 5.48E-05 4.261106784 8.236168828 up GIRDDIEEEDDQEAYFR ddPTM_HeLa_Curcumin_4h_R1 1 GIRDDIEEEDDQEAYFR 17 1 Q86XP3;J3KRE3;A0A0A0MSJ0;Q86XP3-2 Q86XP3 DDX42 ATP-dependent RNA helicase DDX42 0 0 144.15 1.64E-06 0 1607.5 1382 1368.7 1520.2 1655.8 2021.8 1312.1 1866.3 1646.2 1765.6 FALSE FALSE TRUE 1480.264679 1501.453922 1419.425226 1513.909815 1636.055666 1602.45589 1348.913995 2435.326279 1465.615979 1826.954469 0.810236218 0.821834341 0.776935195 0.828652187 0.89550982 0.877118679 0.738340237 1.332997795 0.80221812 1 10.83522496 -4.250500981 24.84919738 0.876657892 1.332998079 0.775437909 0.077400635 677.8935148 1539966.702 0.013190328 0.262297744 5.62E-05 4.250500981 0.456340187 GIS(ph)HVIVDEIHER ddPTM_HeLa_Curcumin_4h_R1 2 GISHVIVDEIHER 13 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 1 0 GIS(1)HVIVDEIHER;GIS(1)HVIVDEIHER ; 135.86 0.00059555 7296500 707.06 832.14 895.76 615.31 758.52 760.81 459.97 275.69 693.32 876.28 TRUE FALSE FALSE 651.0954549 904.0664737 928.9576536 612.7640103 749.4751444 603.0094299 472.8755203 359.7466119 617.2645306 906.7306648 0.718069301 0.997061761 1.024513331 0.675794957 0.826568653 0.665036988 0.521517071 0.396751346 0.680758415 1 9.824530266 -4.602163059 0.757038841 0.882853512 0.223162646 0.626611967 0.122254391 0.890696116 0.482461355 0.021824648 0.447937115 2.50E-05 4.602163059 -0.659690866 GIS(ph)PIVFDR ddPTM_HeLa_Curcumin_4h_R1 3 GISPIVFDR 9 0 J3QR07;Q96MU7-2;Q96MU7 J3QR07 YTHDC1 YTH domain-containing protein 1 1 0 GIS(1)PIVFDR;GIS(1)PIVFDR;GIS(1)PIVFDR ;; 126.71 0.0044982 176266000 10860.3 9838 10773.1 10026.6 11463.1 13278.2 11519.7 8818.4 10638.5 9918.1 TRUE FALSE FALSE 10000.6958 10688.35288 11172.36056 9985.112586 11326.41002 10524.15164 11842.91178 11507.08957 9471.483166 10262.75324 0.974465191 1.041470319 1.088631901 0.972946767 1.10364244 1.025470593 1.153970236 1.121247807 0.922898851 1 13.3251302 -4.512062039 0.38159578 0.986667966 1.234019004 0.552503218 0.047453403 2.452941304 0.279758706 0.012507517 0.26837856 3.08E-05 4.512062039 0.247351039 GISAGAVQTAGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 GISAGAVQTAGKK 13 1 P46087;P46087-4;F5GWB7;F5H709 P46087 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 0 1 ; GISAGAVQTAGK(1)K;GISAGAVQTAGK(1)K 223.31 9.77E-29 7650200 4280.7 4801.3 4102.7 4374 3851.9 5313.6 3231.7 2892.3 3930.5 4119.4 FALSE TRUE FALSE 3941.878078 5216.302978 4254.749671 4355.901547 3805.968608 4211.499463 3322.372804 3774.148955 3499.333984 4262.548843 0.924770184 1.223752072 0.998170303 1.021900677 0.89288563 0.988023743 0.779433369 0.885420694 0.820948712 1 12.05750065 -4.969006458 1.652705979 0.988797214 0.831964563 0.222107649 0.104382766 0.417436026 2.078043375 0.013571576 0.067352106 1.07E-05 4.969006458 -0.156832651 GISHVIVDEIHER ddPTM_HeLa_Curcumin_4h_R1 4 GISHVIVDEIHER 13 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 0 ;;; ;;; 199.4 3.02E-07 35095200 13275.4 12343.3 11797.9 12138.1 12356 14351.1 12197 10142.7 12690.6 12518.5 FALSE FALSE TRUE 12224.63808 13410.19985 12235.14055 12087.87576 12208.66277 11374.52009 12539.21499 13235.16254 11298.47293 12953.51694 0.943731199 1.035255515 0.944541981 0.93317327 0.94249792 0.878102846 0.968016258 1.02174279 0.872232073 1 13.66105623 GISQEQMQEFR ddPTM_HeLa_Curcumin_4h_R1 3 GISQEQMQEFR 11 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 0 ;; ;; 180.09 0.0008071 64814400 4012.3 2743.17 3546.03 3002.18 3635.74 4853.2 3922.78 4074.06 4030.22 3114.08 FALSE FALSE TRUE 3694.722221 2980.277391 3677.448991 2989.757775 3592.386175 3846.591613 4032.842649 5316.222139 3588.114949 3222.294048 1.146612372 0.924893057 1.141251834 0.927835179 1.114853617 1.193743201 1.251543959 1.649825267 1.113528094 1 11.65387244 -3.515865657 0.911501656 1.056256976 3.284904279 0.837284364 0.07936498 2.012028553 0.473355181 0.012645694 6.181853156 0.000304884 3.515865657 2.228647303 ELVSSSSS(ph)GSDSDSEVDKK ddPTM_HeLa_Curcumin_4h_R1 1 ELVSSSSSGSDSDSEVDKK 19 1 P53999;D6RC37;D6R970 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 1 0 ELVS(0.004)S(0.019)S(0.007)S(0.071)S(0.782)GS(0.072)DS(0.044)DSEVDKK 109.12 0.00024699 170640000 5399.9 3847.4 5112.3 5053.6 5119.8 5803.1 2731.4 1218.6 5654.6 3957.7 TRUE FALSE FALSE 4972.492217 4179.952112 5301.766335 5032.689542 5058.749729 4599.471646 2808.035733 1590.14553 5034.304527 4095.22978 1.214215681 1.020688053 1.294619989 1.228915058 1.235278605 1.123129078 0.685684536 0.388292139 1.229309415 1 11.99972869 -4.594816673 2.699675793 1.132504559 0.407048217 0.874237617 0.098018362 0.085684412 1.152775391 0.016336044 0.099074954 2.54E-05 4.594816673 -0.725456342 down GISS(ph)LPR ddPTM_HeLa_Curcumin_4h_R1 1 GISSLPR 7 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 GIS(0.193)S(0.807)LPR 90.15 0.015466 9250600 9536.1 9094.8 7412.2 7943.2 7520.9 10367 9789.5 8437.5 9597.2 8883.3 TRUE FALSE FALSE 8781.307623 9880.913986 7686.902652 7910.333143 7431.21818 8216.76734 10064.16702 11010.05491 8544.411171 9191.994014 0.955321295 1.074947827 0.836260624 0.8605677 0.808444628 0.893904775 1.094883984 1.197787432 0.929549253 1 13.16616214 -4.573904385 4.192990176 0.950232547 1.179374905 0.554488191 0.079752515 0.130130628 4.669031591 0.012350519 0.056010549 2.67E-05 4.573904385 0.229142358 GITGVEDK ddPTM_HeLa_Curcumin_4h_R1 2 GITGVEDK 8 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 0 0 ; ; 111.74 0.0055361 16664200 12734.5 9859.9 11558.9 11080.9 13116.5 14333.2 11484.1 11237.3 11582.6 10949.9 FALSE FALSE TRUE 11726.55089 10712.14582 11987.283 11035.05017 12960.0943 11360.33275 11806.31294 14663.50104 10312.01776 11330.40821 1.03496279 0.945433353 1.057974504 0.973932269 1.143832955 1.002641082 1.042002434 1.294172352 0.910118821 1 13.46791222 -4.261901228 4.225881133 1.020037331 1.315594442 0.655922005 0.061214891 0.079029113 3.191890203 0.006408101 0.070251604 5.47E-05 4.261901228 0.295557112 GIVEFASK(ac)PAAR ddPTM_HeLa_Curcumin_4h_R1 2 GIVEFASKPAAR 12 1 P23246;P23246-2 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 1 ; GIVEFASK(1)PAAR;GIVEFASK(1)PAAR 127.83 0.00052655 22347000 2174.63 2752.6 1850.82 1773.62 3113.2 4807.2 3405 3079 4391.2 2071.3 FALSE TRUE FALSE 2002.505741 2990.522479 1919.413017 1766.28123 3076.077123 3810.132532 3500.535136 4017.772926 3909.496346 2143.277521 0.934319388 1.395303431 0.895550389 0.824102905 1.435221101 1.777713103 1.633262656 1.874592948 1.824073788 1 11.06560295 -5.553696605 3.683778729 0.989277661 1.739226701 0.394279521 0.306402537 0.064789416 1.876022217 0.022544563 0.048950835 2.79E-06 5.553696605 0.74994904 GIVEFASKPAAR ddPTM_HeLa_Curcumin_4h_R1 2 GIVEFASKPAAR 12 1 P23246;P23246-2 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 0 ; ; 147.62 3.24E-05 11179900 6558 4769 5283.4 5918.9 5102.3 7086.8 5484.3 6203.6 7176.8 5876.3 FALSE FALSE TRUE 6038.92738 5181.21111 5479.207452 5894.40916 5041.458405 5616.917795 5638.174698 8095.049082 6389.522995 6080.500988 0.993162799 0.852102667 0.901111185 0.969395313 0.829118919 0.923759047 0.92725496 1.331312847 1.0508218 1 12.56997448 -4.258427045 24.93608589 0.959344061 1.331312988 0.748220971 0.067388574 115.1706731 953331.3722 0.009922701 0.093907797 5.52E-05 4.258427045 0.371968927 GIVEFSGK(ac)PAAR ddPTM_HeLa_Curcumin_4h_R1 2 GIVEFSGKPAAR 12 1 Q15233;Q15233-2;C9IZL7;H7C367 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 1 ; GIVEFSGK(1)PAAR;GIVEFSGK(1)PAAR 145.28 8.41E-05 113330000 5931.2 7188.5 6789 5602.1 5055 14609.1 9864.3 7116 7628.8 8601 FALSE TRUE FALSE 5461.739261 7809.841909 7040.606312 5578.919995 4994.722427 11579.00798 10141.06571 9285.635642 6791.939726 8899.88411 0.61368656 0.877521753 0.791089662 0.626853106 0.561212075 1.301029074 1.139460423 1.043343433 0.763149232 1 13.11957083 -5.253501024 24.99991485 0.786766391 1.159095926 0.641712912 0.139504299 405.3331745 1276494.259 0.025335044 0.063334684 5.58E-06 5.253501024 0.372329535 GIVEFSGKPAAR ddPTM_HeLa_Curcumin_4h_R1 1 GIVEFSGKPAAR 12 1 Q15233;Q15233-2;C9IZL7;H7C367 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 0 112.94 3.23E-05 0 1921.1 1685.8 1740.9 1871.8 1678.4 2722.1 1809.7 1247.1 1954.1 1839.9 FALSE FALSE TRUE 1769.042908 1831.51304 1805.419285 1864.054988 1658.386176 2157.505776 1860.475311 1627.335049 1739.740119 1903.836388 0.929199021 0.962011784 0.948305903 0.979104612 0.871075995 1.13324117 0.977224368 0.854766228 0.913807578 1 10.89469379 GIVPLAK ddPTM_HeLa_Curcumin_4h_R1 1 GIVPLAK 7 0 H7BZJ3;P30101 H7BZJ3;P30101 PDIA3 Protein disulfide-isomerase A3 0 0 106.84 0.015974 2367000 6165.1 4253.9 6649.1 5520.1 5758.9 6641.3 5463.3 3919 5346.6 5120.9 FALSE FALSE TRUE 5677.12583 4621.588161 6895.521495 5497.259289 5690.228879 5263.819517 5616.585494 5113.885059 4760.091357 5298.850894 1.071388107 0.872186867 1.301323935 1.037443664 1.073860917 0.993388873 1.059962925 0.965093218 0.898325213 1 12.37146382 -4.252863827 22.45648817 1.042961528 0.965093057 0.02846181 0.111004622 663.8901289 1738326.302 0.01284582 0.184048105 5.59E-05 4.252863827 -0.077868471 GIWHNDNK ddPTM_HeLa_Curcumin_4h_R1 2 GIWHNDNK 8 0 P12277;H0YJG0;P06732 P12277 CKB;CKM "Creatine kinase B-type;Creatine kinase M-type;Creatine kinase M-type, N-terminally processed" 0 0 ; ; 138.54 0.0026619 51316000 15329.6 13010.6 13936.2 12889.9 13793.6 15556.4 12660.6 13300.4 14668.4 13884 FALSE FALSE TRUE 14116.24598 14135.17829 14452.68783 12836.56501 13629.12033 12329.82728 13015.82236 17355.63073 13059.31322 14366.46797 0.982582916 0.983900728 1.006001466 0.893508762 0.948675789 0.858236507 0.905986245 1.208065251 0.909013492 1 13.81041779 GIWKPET(ph)PQDSSGLAPFK ddPTM_HeLa_Curcumin_4h_R1 1 GIWKPETPQDSSGLAPFK 18 1 A0A0A0MR88;A0A096LPC5;Q641Q2;F8W7U3 A0A0A0MR88;Q641Q2 FAM21C;FAM21A WASH complex subunit FAM21A 1 0 GIWKPET(0.998)PQDS(0.001)S(0.001)GLAPFK 73.294 0.0093717 13200000 1302.4 740.18 1078.5 957.33 1343.8 2165.3 2088.9 995.56 1222.9 785.98 TRUE FALSE FALSE 1199.313666 804.157861 1118.470159 953.3688221 1327.776063 1716.192372 2147.508912 1299.101661 1088.75093 813.2927465 1.47463957 0.988768023 1.375236855 1.172233278 1.632593022 2.11017789 2.640511576 1.597335851 1.338694995 1 9.667630937 -5.459381285 2.570929375 1.218914877 2.174340275 0.674156257 0.276733712 0.121044731 1.56694841 0.04140846 0.102041344 3.47E-06 5.459381285 0.955425399 GIYAYGFEKPSAIQQR ddPTM_HeLa_Curcumin_4h_R1 2 GIYAYGFEKPSAIQQR 16 1 I3L3H2;P38919;J3KT04;J3KS93;J3QQP0;E9PBH4;F8WE11;E7EMV8;J3KSN7;P60842;J3KT12;P60842-2;J3KTB5;J3QS69;J3QL43;E7EQG2;Q14240;Q14240-2;J3QR64;J3QKZ9;J3QLN6;J3KS25 I3L3H2;P60842 EIF4A3;EIF4A1;EIF4A2 "Eukaryotic initiation factor 4A-III;Eukaryotic initiation factor 4A-III, N-terminally processed;Eukaryotic initiation factor 4A-I;Eukaryotic initiation factor 4A-II;Eukaryotic initiation factor 4A-II, N-terminally processed" 0 0 ; ; 136.24 0.00074803 8815400 1233.38 648.69 1004.12 1151.44 1343.37 1198.4 1017.46 729.53 1185.72 629.38 FALSE FALSE TRUE 1135.756672 704.7598731 1041.333571 1146.675646 1327.35119 949.8383312 1046.007189 951.9603387 1055.649483 651.2509082 1.743961747 1.082163363 1.598974462 1.760727904 2.038156375 1.458482928 1.606150834 1.461741284 1.620956638 1 9.347069669 -9.531532679 0.704054562 0.885547816 1.614317647 0 0.303682584 0.789125408 0.514302636 0.370715014 0.048878452 2.94E-10 9.531532679 0.728769831 GK(ac)FEDMAK ddPTM_HeLa_Curcumin_4h_R1 2 GKFEDMAK 8 1 P23497;Q5T7C4;P09429;B2RPK0 P23497;Q5T7C4 SP100;HMGB1;HMGB1P1 Nuclear autoantigen Sp-100;High mobility group protein B1;Putative high mobility group protein B1-like 1 0 1 ; GK(1)FEDMAK;GK(1)FEDMAK 101.65 0.011702 11122200 7921.2 6616.3 6588.7 6193.1 10109.3 12527 11041 10346.5 11594.8 6193.3 FALSE TRUE FALSE 7294.228662 7188.18349 6832.883018 6167.474593 9988.7532 9928.758992 11350.78074 13501.10022 10322.87945 6408.516714 1.138208573 1.121661035 1.066219115 0.962387221 1.55866851 1.549306873 1.771202487 2.106743389 1.610806355 1 12.64577476 -4.853623061 0.777195139 1.057538797 2.266118198 0.678546062 0.20729596 0.277963517 0.193927468 0.019160023 0.243348086 1.40E-05 4.853623061 1.208579401 GK(ac)GEHFPYEQEIK ddPTM_HeLa_Curcumin_4h_R1 1 GKGEHFPYEQEIK 13 1 A0A590UJZ8;H7BY35;Q92736;Q92736-2 A0A590UJZ8 RYR2 Ryanodine receptor 2 0 1 GK(1)GEHFPYEQEIK 115.7 0.00080882 4003400 612.99 1178.3 814.55 610.17 819.87 2166.3 1256 868.89 1249.4 1369.5 FALSE TRUE FALSE 564.4711947 1280.147002 844.7379396 607.6452782 810.0935857 1716.984961 1291.23998 1133.810561 1112.343946 1417.090023 0.398331218 0.903363217 0.596107464 0.428797937 0.571659932 1.211627302 0.911191215 0.800097766 0.784949388 1 10.4687157 -5.278869826 24.85842868 0.684577234 0.967994039 0.317839554 0.203995932 913.4237038 1302678.058 0.037691555 0.084465641 5.26E-06 5.278869826 0.283416806 GK(ac)HGFSDNQK ddPTM_HeLa_Curcumin_4h_R1 1 GKHGFSDNQK 10 1 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 0 1 GK(1)HGFSDNQK 129 0.0020135 2969000 1526.1 1220.5 1269.7 1113.5 1134.8 2113.1 1202.8 1550.2 1556.2 1361.8 FALSE TRUE FALSE 1405.307575 1325.994582 1316.756199 1108.892632 1121.268251 1674.81924 1236.547331 2022.848844 1385.488753 1409.122449 0.997292731 0.94100735 0.934451225 0.786938447 0.795720948 1.188554793 0.877530077 1.435538016 0.983228076 1 10.46058127 -4.254390777 24.6448002 0.969509173 1.435538282 0.630215946 0.111313438 350.6980594 1226145.647 0.015156737 0.202335547 5.57E-05 4.254390777 0.466029109 GK(ac)LDDYQER ddPTM_HeLa_Curcumin_4h_R1 1 GKLDDYQER 9 1 Q14444-2;Q14444;E9PLA9 Q14444-2 CAPRIN1 Caprin-1 0 1 GK(1)LDDYQER 123.79 0.0010449 2843200 1085.9 1262.9 984.66 1085.7 1552.4 2329.6 1823.1 1979.4 2074.1 924.17 FALSE TRUE FALSE 999.9498692 1372.059449 1021.152366 1081.207661 1533.888644 1846.4147 1874.251279 2582.909948 1846.576419 956.2848387 1.045661113 1.434781137 1.067832851 1.130633486 1.604008117 1.930820845 1.959929932 2.700983895 1.930989957 1 9.901296593 -2.343611626 0.377798395 0.99680118 9.632618377 0.609448239 0.328022575 3.649987357 0.114879347 0.038534272 19.60916772 0.004533028 2.343611626 8.635817198 GK(ac)QGGK(ac)AR ddPTM_HeLa_Curcumin_4h_R1 1 GKQGGKAR 8 2 Q93077;Q7L7L0;P04908;A0A3B3IS11;Q96QV6;Q8IUE6;A0A0U1RR32;A0A0U1RRH7;Q99878;Q96KK5;Q16777;Q6FI13;P20671;P0C0S8 Q93077;A0A0U1RR32 HIST1H2AC;HIST3H2A;HIST1H2AB;HIST1H2AA;HIST2H2AB;HIST1H2AJ;HIST1H2AH;HIST2H2AC;HIST2H2AA3;HIST1H2AD;HIST1H2AG Histone H2A type 1-C;Histone H2A type 3;Histone H2A type 1-B/E;Histone H2A type 1-A;Histone H2A type 2-B;Histone H2A type 1-J;Histone H2A type 1-H;Histone H2A type 2-C;Histone H2A type 2-A;Histone H2A type 1-D;Histone H2A type 1 0 2 GK(1)QGGK(1)AR 132.08 0.0025622 26644000 8958.3 6177.9 7110.3 3605.5 5068.5 6123.8 3638.5 2074.6 3830.6 6159.3 FALSE TRUE FALSE 8249.241102 6711.890148 7373.813973 3590.581396 5008.061448 4853.654851 3740.586517 2707.13599 3410.392764 6373.335217 1.294336611 1.053120528 1.156978838 0.563375576 0.785783468 0.761556498 0.586911937 0.424759706 0.535103309 1 12.63783283 -6.265282045 24.9133946 1.135942681 0.638967407 0.361401575 0.224225541 120.7312264 782744.2975 0.02235763 0.034955617 5.43E-07 6.265282045 -0.496975275 GK(ac)VGRPTASK ddPTM_HeLa_Curcumin_4h_R1 1 GKVGRPTASK 10 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 0 1 GK(1)VGRPTASK 75.566 0.01271 20837000 5890.5 4054.4 5516.1 4693.3 5254.8 6349.3 6115.2 6122.2 5915.1 4936.6 FALSE TRUE FALSE 5424.260709 4404.84427 5720.531518 4673.880368 5192.139942 5032.383609 6286.776054 7988.830597 5266.228329 5108.146483 1.061884331 0.862317532 1.119884001 0.914985579 1.01644304 0.985168226 1.230735273 1.563939214 1.030947007 1 12.31858418 -4.382420369 2.243172389 1.0125961 1.631688405 0.860405032 0.070423198 0.116604997 0.810122443 0.009320161 0.127800325 4.15E-05 4.382420369 0.619092305 GKAS(ph)PFEEDQNR ddPTM_HeLa_Curcumin_4h_R1 1 GKASPFEEDQNR 12 1 C9JW01;A0A0A0MR59;Q8TB72-2;Q8TB72-4;Q8TB72-3;Q8TB72;A0A0C4DG68 C9JW01 PUM2 Pumilio homolog 2 1 0 GKAS(1)PFEEDQNR 72.289 0.01493 67231000 4157.1 3702.5 3915.7 3836.4 4876.7 4279.7 3244.7 2897.9 4344.3 3553 TRUE FALSE FALSE 3828.061148 4022.527602 4060.819287 3820.525993 4818.548538 3392.041978 3335.737549 3781.45637 3867.741159 3676.466486 1.041233794 1.094128729 1.104544079 1.03918423 1.310646665 0.922636448 0.907321626 1.02855728 1.052026769 1 11.84410412 GKDETDSPTVHLGLDS(ph)DS(ph)ESELVIDLGEDHSGR ddPTM_HeLa_Curcumin_4h_R1 1 GKDETDSPTVHLGLDSDSESELVIDLGEDHSGR 33 1 Q9ULU4-9;Q9ULU4-11;Q9ULU4-23;Q9ULU4-21;Q9ULU4;Q9ULU4-5;H7C4X9;A0A087WYS3;A0A087WVZ6;Q9ULU4-10;Q9ULU4-13;Q9ULU4-20;Q9ULU4-12;Q9ULU4-7;Q9ULU4-19;Q9ULU4-16;Q9ULU4-22;Q9ULU4-18;Q9ULU4-14;Q9ULU4-15;Q9ULU4-6;Q9ULU4-3;Q9ULU4-4;Q9ULU4-8;Q9ULU4-17;Q9ULU4-2 Q9ULU4-9 ZMYND8 Protein kinase C-binding protein 1 2 0 GKDET(0.001)DS(0.004)PT(0.003)VHLGLDS(0.634)DS(0.847)ES(0.511)ELVIDLGEDHSGR 65.141 5.89E-05 5327600 1044.6 939.88 796.3 915.47 1112 1593 973.26 903.33 1178.1 860.91 TRUE FALSE FALSE 961.9188077 1021.119039 825.8115785 911.6820277 1098.740126 1262.593843 1000.567056 1178.751159 1048.865377 890.8265584 1.079804816 1.146260211 0.927017241 1.023411369 1.233393993 1.41732847 1.123189522 1.323210615 1.177406946 1 9.79900076 -5.701761412 4.938911867 1.037390479 1.27851915 0.541357459 0.096452226 0.095101046 4.653309027 0.01214625 0.024448391 1.99E-06 5.701761412 0.241128671 GKELSDQATAS(ph)PIVAR ddPTM_HeLa_Curcumin_4h_R1 4 GKELSDQATASPIVAR 16 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 GKELSDQAT(0.201)AS(0.799)PIVAR;GKELSDQAT(0.004)AS(0.996)PIVAR;GKELSDQAT(0.022)AS(0.978)PIVAR;GKELSDQAT(0.214)AS(0.786)PIVAR ;;; 159.14 0.00016654 102655300 22445.7 16897.4 17675.1 19387.2 18428.3 25280.6 19001.3 12361.4 23519.6 19133.1 TRUE FALSE FALSE 20669.09916 18357.93596 18330.15475 19306.9809 18208.55456 20037.11859 19534.42534 16130.33396 20939.55872 19797.9738 1.044000733 0.927263373 0.925860138 0.975199841 0.919718085 1.012079256 0.986688109 0.814746707 1.057661705 1 14.27306517 -7.257867065 24.97711342 1.020778124 0.942469689 0.40654119 0.052479852 257.0392587 1797184.455 0.008363636 0.010030558 5.52E-08 7.257867065 -0.078308435 GKEMVDY(ph)MANY(ph)MEGIEGR ddPTM_HeLa_Curcumin_4h_R1 1 GKEMVDYMANYMEGIEGR 18 1 F8WER1;A0A087WV24;P20711-2;P20711-3;P20711;C9JMP0;A0A087WU57;P20711-4 F8WER1 DDC Aromatic-L-amino-acid decarboxylase 2 0 GKEMVDY(1)MANY(1)MEGIEGR 60.541 0.0060343 0 1468.5 911.66 1269.4 1173.8 980.03 1400.2 1103.5 767.21 1257 1184.2 TRUE FALSE FALSE 1352.266675 990.4598281 1316.445081 1168.943127 968.3437823 1109.782736 1134.46124 1001.128797 1119.110245 1225.350862 1.10357508 0.808307122 1.074341335 0.953966054 0.790258376 0.905685686 0.925825635 0.81701399 0.913297799 1 10.25897919 -6.406005156 0.891736777 1.042653174 0.866195387 0.118620844 0.095934802 0.420715429 0.665654329 0.017131077 0.034576414 3.93E-07 6.406005156 -0.176457786 GKFGHEFLEFEFRPDGK ddPTM_HeLa_Curcumin_4h_R1 1 GKFGHEFLEFEFRPDGK 17 2 F5H6N1;P61326;Q96A72;P61326-2 F5H6N1 MAGOHB;MAGOH Protein mago nashi homolog;Protein mago nashi homolog 2 0 0 48.351 0.02026 22280000 7450.7 5168 6385.7 6613.6 5173 8250.6 6636.8 6389.2 8123.7 6558.7 FALSE FALSE TRUE 6860.969233 5614.698892 6622.359659 6586.234676 5111.315354 6539.332557 6823.010746 8337.237668 7232.550434 6786.614337 1.01095611 0.827319575 0.975797258 0.970474282 0.753146576 0.963563307 1.00536297 1.228482606 1.065708183 1 12.72847632 -4.263407208 3.245165217 0.968039026 1.264677225 0.463276853 0.088595818 0.246101326 4.099125754 0.012428506 0.182560934 5.45E-05 4.263407208 0.296638199 GKGDK(ac)AQIEK ddPTM_HeLa_Curcumin_4h_R1 2 GKGDKAQIEK 10 2 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 1 ; GK(0.001)GDK(0.999)AQIEK;GK(0.001)GDK(0.999)AQIEK 96.334 0.0032799 7401000 6250.5 5363.9 6310.8 6728.5 8067.5 9470.3 7122.3 6092.4 6875.5 5036.4 FALSE TRUE FALSE 5755.76633 5827.531615 6544.6838 6700.65925 7971.300332 7506.053028 7322.132569 7949.944714 6121.274852 5211.414525 1.104453753 1.118224541 1.255836351 1.285765931 1.529584778 1.44031011 1.40501826 1.525486924 1.174589897 1 12.3474593 -6.436582317 0.78401301 1.035206135 1.48817405 0.85199227 0.067829049 0.113027359 0.138340562 0.011084473 0.023032491 3.66E-07 6.436582317 0.452967916 GKGFSVVADT(ph)PELQR ddPTM_HeLa_Curcumin_4h_R1 1 GKGFSVVADTPELQR 15 1 C9J9W2;Q14847;Q14847-2;Q14847-3 C9J9W2 LASP1 LIM and SH3 domain protein 1 1 0 GKGFSVVADT(1)PELQR 80.733 0.01247 161540000 6017 4859.3 4612.7 5607 4574.3 9348.8 7229.7 2209.9 7340.2 4559.1 TRUE FALSE FALSE 5540.748101 5279.316239 4783.65072 5583.79972 4519.75446 7409.753497 7432.545924 2883.688337 6534.998424 4717.528386 1.174502334 1.119085209 1.014016309 1.183628219 0.958076792 1.570685514 1.575516948 0.611271009 1.385258951 1 12.20381548 -5.299450586 24.99650308 1.08234984 1.284794311 0.03146728 0.275433254 842.3434511 553931.1308 0.034473307 0.077085856 5.02E-06 5.299450586 0.202444471 GKGGEIQPVSVK(ac)VGDK ddPTM_HeLa_Curcumin_4h_R1 2 GKGGEIQPVSVKVGDK 16 2 P61604;B8ZZL8 P61604 HSPE1 "10 kDa heat shock protein, mitochondrial" 0 1 ; GKGGEIQPVSVK(1)VGDK;GKGGEIQPVSVK(1)VGDK 146.67 0.00051675 13231000 13158.1 9967.6 11238.4 12323.1 12251 20521 15238.7 14674.8 13746.1 10089.1 FALSE TRUE FALSE 12116.6225 10829.15493 11654.90499 12272.11028 12104.91483 16264.71328 15666.25691 19149.07897 12238.18722 10439.69547 1.16062988 1.037305634 1.116402774 1.175523779 1.159508422 1.557968173 1.500643093 1.83425647 1.17227435 1 13.34979201 -4.35478631 0.596952663 1.065345742 2.254607876 0.896466914 0.081893685 0.651539546 0.168092908 0.015032287 0.519677759 4.42E-05 4.35478631 1.189262134 GKGGVTGS(ph)PEASIS(ph)GSKGDLK ddPTM_HeLa_Curcumin_4h_R1 1 GKGGVTGSPEASISGSKGDLK 21 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 GKGGVT(0.419)GS(0.557)PEAS(0.095)IS(0.806)GS(0.123)KGDLK 61.526 0.0073449 32378000 4459.2 4213.4 4212.3 4111.8 4369.3 7047.8 7539.8 849.03 5413.1 3824.3 TRUE FALSE FALSE 4106.249615 4577.587521 4368.411544 4094.786461 4317.198951 5586.006835 7751.346496 1107.895339 4819.296473 3957.19414 1.03766696 1.156776079 1.103916409 1.034770172 1.090974766 1.411607982 1.958798639 0.279969923 1.217856972 1 11.95026213 -5.418828984 5.715111043 1.038911831 1.289398731 0 0.391650627 0.44072412 20.17884407 0.049652606 0.112160205 3.81E-06 5.418828984 0.250486899 GKGGVTGS(ph)PEASISGSK ddPTM_HeLa_Curcumin_4h_R1 3 GKGGVTGSPEASISGSK 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GKGGVT(0.005)GS(0.995)PEASISGSK;GKGGVTGS(0.992)PEAS(0.007)IS(0.001)GSK;GKGGVT(0.001)GS(0.992)PEAS(0.001)IS(0.003)GS(0.003)K ;; 160.47 0.00053763 2913118000 16109.3 13262.1 14421.5 16524.8 15972.7 19743.3 17439.8 8346.8 16544 12109.2 TRUE FALSE FALSE 14834.23191 14408.41683 14955.97348 16456.42476 15782.23598 15648.31703 17929.11385 10891.7009 14729.16459 12529.9938 1.183897785 1.149914123 1.193613797 1.313362562 1.259556568 1.248868697 1.430895668 0.869250302 1.17551252 1 13.61309808 -8.771688686 0.488177571 0.977134001 1.233410481 0.042342027 0.145754149 1.155422009 0.491304524 0.137537318 0.037816617 1.69E-09 8.771688686 0.25627648 GKGGVTGS(ph)PEASISGSKGDLK ddPTM_HeLa_Curcumin_4h_R1 1 GKGGVTGSPEASISGSKGDLK 21 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GKGGVT(0.076)GS(0.913)PEAS(0.009)IS(0.001)GS(0.001)KGDLK 59.55 0.0090112 221710000 1808 1647.5 1538.3 1748.4 1188 2287.2 1658.8 880.24 3050.3 2186 TRUE FALSE FALSE 1664.894892 1789.902559 1595.310751 1741.165584 1173.833876 1812.808938 1705.341464 1148.621124 2715.689721 2261.963337 0.736039734 0.79130485 0.705277015 0.769758535 0.518944696 0.801431618 0.753920913 0.507798294 1.200589628 1 11.14335983 -13.52287875 0.155453475 2.177460095 0.602204708 0.677940232 0.110102201 29.03779213 0.304203202 10.34170432 0.182874179 3.00E-14 13.52287875 -1.575255386 GKGGVTGSPEASISGS(ph)KGDLK ddPTM_HeLa_Curcumin_4h_R1 2 GKGGVTGSPEASISGSKGDLK 21 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GKGGVTGSPEASIS(0.065)GS(0.935)KGDLK;GKGGVTGSPEASIS(0.224)GS(0.775)KGDLK ; 137.58 2.94E-05 115045000 4651 4539.7 4088.2 5057.1 3834.8 5386 5528.4 1385.15 5704.1 3906.6 TRUE FALSE FALSE 4282.868442 4932.091439 4239.712288 5036.17506 3789.072515 4268.882887 5683.512025 1807.475859 5078.374501 4042.354059 1.059498594 1.220103773 1.048822598 1.245852042 0.937343058 1.056038839 1.405990653 0.447134475 1.256291366 1 11.98097997 -4.240640308 24.9035003 1.072026461 0.447133833 0.637532221 0.148965197 2387.398216 2858476.868 0.018212015 1.097932958 5.75E-05 4.240640308 -0.624892628 GKGS(ph)PRPQAPK ddPTM_HeLa_Curcumin_4h_R1 2 GKGSPRPQAPK 11 2 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 0 GKGS(1)PRPQAPK;GKGS(1)PRPQAPK ; 50.108 0.019328 2841900000 16603.9 17614.6 15346.3 14768.7 16885.6 23769 17580.7 15277.3 19158.1 19179.4 TRUE FALSE FALSE 15289.68379 19137.12753 15915.04738 14707.59103 16684.25025 18839.04147 18073.96713 19935.27844 17056.50436 19845.88272 0.770420949 0.964287041 0.801931947 0.741090293 0.840690761 0.949266996 0.910716211 1.004504497 0.859448007 1 14.27655211 -4.395313192 1.40540509 0.875418547 1.02795498 0.223261816 0.079775167 1.677612102 3.512250575 0.015180022 0.334128422 4.02E-05 4.395313192 0.152536433 GKGTNSSDS(ph)EELSAGESITK ddPTM_HeLa_Curcumin_4h_R1 1 GKGTNSSDSEELSAGESITK 20 1 H7C5R6;Q4LE39-2;Q4LE39 H7C5R6 ARID4B AT-rich interactive domain-containing protein 4B 1 0 GKGT(0.034)NS(0.121)S(0.35)DS(0.476)EELS(0.011)AGES(0.007)IT(0.001)K 49.851 0.016956 15100000 2796.5 2342.9 2573.2 2934.6 2785.5 3212.8 2028.4 1771.9 3054.7 2301.8 TRUE FALSE FALSE 2575.154074 2545.409836 2668.565056 2922.457403 2752.284732 2546.429064 2085.311445 2312.144153 2719.607052 2381.787379 1.08118554 1.06869734 1.120404399 1.227001801 1.155554336 1.069125266 0.875523761 0.9707601 1.141834522 1 11.21782891 -4.773568916 24.79487826 1.070631211 0.923141947 0.471050372 0.069894304 145.7741272 297990.1444 0.011320225 0.034339615 1.68E-05 4.773568916 -0.147489263 GKHSLDS(ph)DEEEDDDDGGSSK ddPTM_HeLa_Curcumin_4h_R1 2 GKHSLDSDEEEDDDDGGSSK 20 1 O95400 O95400 CD2BP2 CD2 antigen cytoplasmic tail-binding protein 2 1 0 GKHS(0.192)LDS(0.808)DEEEDDDDGGSSK;GKHS(0.225)LDS(0.775)DEEEDDDDGGSSK ; 93.92 0.00039806 21743000 11547.9 9476.6 10110.2 10386.6 12611.5 12789.3 10751.9 9994.4 9442.5 8908.5 TRUE FALSE FALSE 10633.87153 10295.71508 10484.89291 10343.623 12461.1161 10136.65501 11053.56938 13041.64655 8406.681374 9218.069712 1.153589836 1.116905751 1.137428251 1.122102927 1.351814044 1.099650505 1.199119742 1.414791487 0.911978498 1 13.17024896 -1.000000006 0.067640222 0.772082422 2.095258496 0.607491692 0.087930676 137.1593891 0.693962497 2.509749144 17.49460871 0.099999999 1.000000006 1.323176075 GKIEVLDS(ph)PASK ddPTM_HeLa_Curcumin_4h_R1 2 GKIEVLDSPASK 12 1 Q8N5I9 Q8N5I9 C12orf45 Uncharacterized protein C12orf45 1 0 GKIEVLDS(0.999)PAS(0.001)K;GKIEVLDS(0.818)PAS(0.182)K ; 153.79 0.0036653 328215000 7854.1 6173.9 6989.1 6365.8 6504.8 8128.2 7625.7 3042.51 8173 6724.7 TRUE FALSE FALSE 7232.439697 6707.544406 7248.122194 6339.460006 6427.234508 6442.319696 7839.656618 3970.157293 7276.442348 6958.382824 1.039385139 0.963951621 1.041638895 0.911053641 0.923667851 0.925835767 1.126649225 0.570557469 1.045708828 1 12.76453634 -4.251138527 24.92266253 1.002557854 0.570557218 0.795496969 0.064903148 448.6460276 1085466.35 0.008662422 0.162246042 5.61E-05 4.251138527 -0.432000636 GKLEAIITPPPAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 GKLEAIITPPPAKK 14 2 O75367-2;O75367-3;O75367;D6RCF2 O75367-2 H2AFY Core histone macro-H2A.1;Histone H2A 0 1 ; GKLEAIITPPPAK(1)K;GKLEAIITPPPAK(1)K 90.229 0.003963 7773200 8631.1 4914.6 7990.9 8262.6 8916.1 9846.1 7848.1 6545.8 9981.8 5690.9 FALSE TRUE FALSE 7947.939328 5339.396125 8287.049784 8228.411551 8809.781331 7803.907872 8068.296564 8541.584287 8886.821513 5888.658351 1.349702912 0.906725404 1.407289961 1.397332136 1.496059171 1.325243783 1.370141734 1.450514494 1.509141978 1 12.52372326 -12.82098784 0.140741573 7.41E-19 1.497050051 0 0.209017751 38.97087829 0.459303627 11.34039456 0.433923079 1.51E-13 12.82098784 1.497050051 GKLPIVNEDDELVAIIAR ddPTM_HeLa_Curcumin_4h_R1 1 GKLPIVNEDDELVAIIAR 18 1 P12268;H0Y4R1;E7ETK5 P12268 IMPDH2 Inosine-5-monophosphate dehydrogenase 2 0 0 73.735 0.0095371 9455700 1663.9 1002 1307.6 1319.5 1245.8 895.77 874.59 1104.6 1538.5 1310.1 FALSE FALSE TRUE 1532.200559 1088.608415 1356.060806 1314.040259 1230.944649 709.9772046 899.1286416 1441.387455 1369.730399 1355.625877 1.130253254 0.803030123 1.000320832 0.969323676 0.908026816 0.523726506 0.663257213 1.063263456 1.010404435 1 10.40474337 -5.584436427 3.298346185 1.030823794 0.738054765 0.293061106 0.151183181 0.176841197 3.903002755 0.022464983 0.048835565 2.60E-06 5.584436427 -0.292769029 GKLS(ph)AEENPDDSEVPSSSGINSTK ddPTM_HeLa_Curcumin_4h_R1 2 GKLSAEENPDDSEVPSSSGINSTK 24 1 A0A494C1S7;Q9Y5Q9-2;Q9Y5Q9 A0A494C1S7 GTF3C3 General transcription factor 3C polypeptide 3 1 0 GKLS(0.777)AEENPDDS(0.217)EVPS(0.004)S(0.001)SGINSTK;GKLS(0.569)AEENPDDS(0.431)EVPSSSGINSTK ; 79.731 0.00011395 310780000 10901.5 8473.6 9490.2 9626.4 9290.9 11676 7811.4 4963.4 10991.6 10602.9 TRUE FALSE FALSE 10038.63477 9206.020226 9841.91516 9586.568507 9180.112086 9254.265984 8030.566861 6476.717811 9785.84898 10971.34999 0.914986286 0.839096395 0.897055984 0.873782034 0.836734959 0.843493827 0.731957951 0.590330071 0.891945749 1 13.42145343 -2.872414784 0.269367914 0.982017907 1.30E-20 0.80037806 0.047349737 4.727835445 0.14366264 0.022086115 1.769225399 0.001341483 2.872414784 -0.982017907 GKPASGAGAGAGAGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GKPASGAGAGAGAGKR 16 2 O43818 O43818 RRP9 U3 small nucleolar RNA-interacting protein 2 0 1 ; GKPASGAGAGAGAGK(1)R;GKPASGAGAGAGAGK(1)R 109.14 0.00064088 11138700 3164.1 2926.1 3309.1 3031.9 3451.2 3833.3 3259.1 3102.9 3688.2 2598.3 FALSE TRUE FALSE 2913.658146 3179.019046 3431.738157 3019.354801 3410.046694 3038.23037 3350.541575 4048.959926 3283.613687 2688.590732 1.08371204 1.182410922 1.276407791 1.123025072 1.268339824 1.130045691 1.246207366 1.505978533 1.221314069 1 11.39263444 -1 0.146534917 0.945705269 2.511538525 0.333433169 0.106835056 30.27296945 0.28903108 0.192397233 10.06629216 0.1 1 1.565833256 LSS(ph)DDGDSSTMR ddPTM_HeLa_Curcumin_4h_R1 1 LSSDDGDSSTMR 12 0 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 1 0 LS(0.002)S(0.998)DDGDSSTMR 168.98 2.33E-09 0 500.29 430.31 332.1 824.71 577.82 550.12 656.45 3199.5 568.01 473.86 TRUE FALSE FALSE 460.6915186 467.504079 344.4079181 821.2975685 570.9298739 436.0189109 674.8682203 4175.012821 505.7007241 490.3265997 0.939560527 0.953454451 0.702405128 1.675001048 1.164386909 0.889241806 1.376364694 8.514758986 1.031354865 1 8.937599218 -4.261065983 4.970789243 1.01293572 8.892997427 0.988433759 0.241448413 0.01165077 0.880251016 0.032683983 0.314750647 5.48E-05 4.261065983 7.880061706 up GKPSPWQS(ph)S(ph)TS(ph)TGES(ph)SKEAQK ddPTM_HeLa_Curcumin_4h_R1 1 GKPSPWQSSTSTGESSKEAQK 21 2 Q5VVP1 Q5VVP1 SPATA31A6 Spermatogenesis-associated protein 31A6 4 0 GKPS(0.102)PWQS(0.581)S(0.589)T(0.594)S(0.561)T(0.573)GES(0.623)S(0.376)KEAQK 42.58 0.018689 10043000 1056.7 1038.1 990.87 1021.6 1255.7 1318.5 950.08 890.36 1189.7 768.28 TRUE FALSE FALSE 973.06108 1127.828738 1027.592514 1017.37289 1240.726598 1045.028237 976.7366878 1161.826665 1059.192886 794.9776728 1.224010577 1.418692344 1.292605502 1.279750268 1.560706219 1.314537846 1.228634113 1.461458233 1.332355515 1 9.634770532 -8.200372189 0.56881143 1.00286396 1.373502565 0.096227826 0.137582426 0.325065993 0.235755309 0.052307278 0.02786813 6.30E-09 8.200372189 0.370638605 GKSEEELEAS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 GKSEEELEASK 11 1 Q7RTP6;J3QR21;A0A5F9ZHV5 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 0 GKSEEELEAS(1)K 148.28 0.0072918 9776000 1208 1160.6 1335.2 1079.6 1010.1 1353.2 1538.3 1540.2 1368.6 1021.8 TRUE FALSE FALSE 1112.385525 1260.917092 1384.683687 1075.132901 998.0552172 1072.531066 1581.460558 2009.79989 1218.468004 1057.307474 1.052092748 1.192573706 1.309631986 1.016859265 0.943959295 1.014398453 1.495743288 1.900866058 1.152425415 1 10.04617927 -4.521366741 2.611247464 1.050034697 1.901939855 0.84549963 0.110326088 0.085386052 1.019876088 0.016340912 0.122252466 3.01E-05 4.521366741 0.851905158 GKT(ph)SGTEPADFALPSSR ddPTM_HeLa_Curcumin_4h_R1 1 GKTSGTEPADFALPSSR 17 1 A6NNK5;Q12888;Q12888-3;Q12888-2;M0R142 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 GKT(0.755)S(0.232)GT(0.012)EPADFALPSSR 122.08 0.0053501 5989300 1084.7 793.27 1043.2 935.53 988.54 1541.1 1269 995.69 1495.1 1058.4 TRUE FALSE FALSE 998.8448504 861.8367241 1081.86191 931.6590247 976.7523061 1221.458488 1304.604725 1299.271297 1331.091271 1095.179321 0.912037719 0.78693663 0.987839972 0.850690847 0.891865183 1.115304557 1.191224761 1.186354848 1.215409426 1 10.0969514 -5.115232257 3.854904013 0.934697726 1.183098663 0.455343437 0.108555973 0.098275976 2.560514093 0.010132262 0.028221185 7.67E-06 5.115232257 0.248400938 GKT(ph)T(ph)QVVS(ph)ADSTIQMLFY(ph)MEK ddPTM_HeLa_Curcumin_4h_R1 1 GKTTQVVSADSTIQMLFYMEK 21 1 Q96RY7 Q96RY7 IFT140 Intraflagellar transport protein 140 homolog 4 0 GKT(0.997)T(0.997)QVVS(0.534)ADS(0.362)T(0.111)IQMLFY(0.999)MEK 54.656 0.0052655 77115000 890.38 729.41 847.54 1004.3 985.09 1179.3 1047.4 492.82 984.63 1056.3 TRUE FALSE FALSE 819.9054835 792.4569502 878.950578 1000.144473 973.3434451 934.6998865 1076.787225 643.0785493 876.6185524 1093.006346 0.750137898 0.725025022 0.804158714 0.91503995 0.890519482 0.85516419 0.985161 0.588357562 0.802025126 1 10.09408606 -9.434727147 1.185633882 0.99923441 0.817188275 0 0.120775807 0.474403816 1.200614739 0.069701101 0.01776055 3.68E-10 9.434727147 -0.182046135 GLAAEDS(ph)GGDSK ddPTM_HeLa_Curcumin_4h_R1 1 GLAAEDSGGDSK 12 0 P41227;P41227-2 P41227 NAA10 N-alpha-acetyltransferase 10 1 0 GLAAEDS(0.992)GGDS(0.008)K 147.73 0.00070269 37817000 3293.6 3034.4 3376.5 3174.9 4073.5 3646.3 3254.2 3261.2 2985.2 2611.3 TRUE FALSE FALSE 3032.908085 3296.680015 3501.63606 3161.763105 4024.926173 2890.016278 3345.504094 4255.524867 2657.731029 2702.042481 1.122450186 1.220069647 1.295921913 1.170138193 1.489586563 1.069567299 1.23813897 1.574928928 0.983600757 1 11.39983464 -1 0.075341951 0.701417053 2.532391869 0.511371927 0.12956106 121.0107548 0.67515004 2.714701553 23.36194733 0.1 1 1.830974815 GLAAEDS(ph)GGDSKDLSEVSETTESTDVK ddPTM_HeLa_Curcumin_4h_R1 1 GLAAEDSGGDSKDLSEVSETTESTDVK 27 1 P41227;P41227-2 P41227 NAA10 N-alpha-acetyltransferase 10 1 0 GLAAEDS(0.874)GGDS(0.109)KDLS(0.017)EVSETTESTDVK 117.62 3.35E-09 31688000 1530 1449.5 1715.9 1228.2 2027.3 1724.4 1652.7 1457.5 1510.5 1230.1 TRUE FALSE FALSE 1408.898886 1574.788321 1779.492763 1223.118034 2003.125772 1366.740002 1699.070314 1901.88504 1344.801929 1272.845883 1.106888826 1.237218379 1.398042596 0.960931759 1.573737872 1.073767076 1.334859417 1.494198996 1.056531625 1 10.31384203 -1.000000035 0.087450117 0.764387 2.548462402 0.330960251 0.167986289 110.3024287 0.701892519 1.993539093 23.75356923 0.099999992 1.000000035 1.784075402 GLAEVQQDGEAEEGAT(ph)SDGEK ddPTM_HeLa_Curcumin_4h_R1 1 GLAEVQQDGEAEEGATSDGEK 21 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 GLAEVQQDGEAEEGAT(0.83)S(0.17)DGEK 133.98 3.05E-05 13167000 2083.8 1824.4 1862.1 2109.3 2311.2 2019.2 2060.6 1732.9 2066.3 1724.8 TRUE FALSE FALSE 1918.865031 1982.093007 1931.111064 2100.572275 2283.640449 1600.395159 2118.41489 2261.253233 1839.63206 1784.736672 1.075153025 1.110580086 1.08201456 1.17696482 1.279539153 0.896712207 1.186962157 1.266995445 1.030758256 1 10.80149551 -1.000136489 0.027614219 0.353577149 2.181192355 0.24243098 0.099110799 1378.345359 2.952749189 65.0026556 145.6871632 0.099968577 1.000136489 1.827615206 GLAEVQQDGEAEEGAT(ph)SDGEKKR ddPTM_HeLa_Curcumin_4h_R1 3 GLAEVQQDGEAEEGATSDGEKKR 23 2 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 GLAEVQQDGEAEEGAT(0.5)S(0.5)DGEKKR;GLAEVQQDGEAEEGAT(0.56)S(0.44)DGEKKR;GLAEVQQDGEAEEGAT(0.713)S(0.287)DGEKKR ;; 65.744 0.0011318 287911000 9461.3 7617.3 7782.1 7711.8 6828 10074.4 8077.2 7339 9106.5 8708.4 TRUE FALSE FALSE 8712.428121 8275.70547 8070.511472 7679.890615 6746.58056 7984.855878 8303.824493 9576.627315 8107.539733 9011.016252 0.9668641 0.918398684 0.895627224 0.852277967 0.748703628 0.886121571 0.921519201 1.062768843 0.899736446 1 13.13747411 -7.238403998 1.633752306 0.987640288 0.88665102 0.067296538 0.077763599 0.369795028 1.874227528 0.01426517 0.017076546 5.78E-08 7.238403998 -0.100989268 GLAEVQQDGEAEEGATS(ph)DGEK ddPTM_HeLa_Curcumin_4h_R1 1 GLAEVQQDGEAEEGATSDGEK 21 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 GLAEVQQDGEAEEGAT(0.291)S(0.709)DGEK 56.442 0.0077626 12647000 1434.7 1401.2 1575.1 1306.5 1542.4 1824.1 1604.2 1481.2 1789.6 1460.3 TRUE FALSE FALSE 1321.141981 1522.313484 1633.474592 1301.094049 1524.007887 1445.761098 1649.209535 1932.811061 1593.285357 1511.045316 0.874323203 1.007457201 1.081022901 0.861055612 1.008578546 0.956795327 1.091436184 1.279121837 1.054425926 1 10.56133121 -4.310518242 1.606327095 0.952667482 1.382356135 0.609663174 0.070768377 0.412088254 1.071764109 0.010103816 0.267132731 4.89E-05 4.310518242 0.429688654 GLAEVQQDGEAEEGATS(ph)DGEKKR ddPTM_HeLa_Curcumin_4h_R1 1 GLAEVQQDGEAEEGATSDGEKKR 23 2 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 GLAEVQQDGEAEEGAT(0.267)S(0.733)DGEKKR 61.538 0.0046661 105300000 4298.4 3416.7 3682 3775.7 3279.8 4876.3 4001.7 3623.8 4610.6 4417.6 TRUE FALSE FALSE 3958.177104 3712.024323 3818.458159 3760.077154 3240.690527 3864.900413 4113.976932 4728.679938 4104.828715 4571.111271 0.865911344 0.812061685 0.835345703 0.822573972 0.708950261 0.845505651 0.899994922 1.034470538 0.897993611 1 12.15832922 -8.797898908 0.777678092 0.996576949 0.846549744 0.135592437 0.082606637 0.558251138 0.652167188 0.045881109 0.017126852 1.59E-09 8.797898908 -0.150027204 GLAGPPAS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 3 GLAGPPASPGK 11 0 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 1 0 GLAGPPAS(1)PGK;GLAGPPAS(1)PGK;GLAGPPAS(1)PGK ;; 110.38 0.0065741 464231000 24916.3 20075.5 23194.7 22698.1 25587.3 23466.5 17086.5 12033.5 24353.3 18121.5 TRUE FALSE FALSE 22944.14856 21810.73677 24054.31599 22604.18128 25282.18816 18599.28338 17565.9012 15702.45875 21681.80392 18751.22078 1.223608257 1.163163563 1.282813331 1.205477848 1.348295584 0.9918972 0.936787072 0.837409945 1.156287592 1 14.1946969 -5.028951597 8.082215276 1.148518992 0.905481236 0.611165129 0.097361859 0.177819314 45.17878735 0.017702767 0.04678991 9.36E-06 5.028951597 -0.243037757 GLAGPPAS(ph)PGKAQPPKPER ddPTM_HeLa_Curcumin_4h_R1 1 GLAGPPASPGKAQPPKPER 19 2 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 1 0 GLAGPPAS(1)PGKAQPPKPER 41.256 0.020043 65227000 2128.9 1776 1256.3 2058.4 1284.6 1871.8 1139.3 1105.9 2684 2154.1 TRUE FALSE FALSE 1960.395319 1929.509526 1302.859583 2049.882886 1269.281984 1483.56758 1171.265692 1443.083819 2389.571915 2228.954815 0.879513261 0.865656636 0.584515924 0.919661032 0.569451644 0.665588899 0.52547754 0.647426233 1.072059379 1 11.12215166 -6.546215238 0.365044286 1.003320207 0.529304975 0.690336788 0.103799423 0.582458897 0.171938792 0.047123956 0.107032137 2.84E-07 6.546215238 -0.474015232 GLALALFGGEPK ddPTM_HeLa_Curcumin_4h_R1 2 GLALALFGGEPK 12 0 P49736;H0Y8E6 P49736 MCM2 DNA replication licensing factor MCM2 0 0 ; ; 147.4 6.93E-05 1155540 950.22 569.588 574.95 550.13 595.81 1648.16 1145.8 1071.28 785.525 927.83 FALSE FALSE TRUE 875.0090843 618.8206487 596.2581528 547.8537078 588.7053549 1306.313037 1177.948064 1397.90834 699.3548728 960.0720234 0.911399419 0.644556485 0.621055648 0.570638134 0.613188741 1.360640666 1.226937183 1.456045282 0.728440008 1 9.906998829 -5.243940603 24.61077575 0.857495325 1.335780743 0.689940688 0.17607285 424.0051986 596331.5664 0.03022624 0.076851438 5.70E-06 5.243940603 0.478285418 GLANPEPAPEPKLS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 GLANPEPAPEPKLSR 15 1 O15027-4;A0A3F2YNZ0 O15027-4 SEC16A Protein transport protein Sec16A 1 0 GLANPEPAPEPKLS(1)R 140.49 0.005115 4668400 1711.7 1134 1548 1738.1 1486.1 1733.6 782.18 653.54 1707.3 1493.9 TRUE FALSE FALSE 1576.217139 1232.017907 1605.370242 1730.908203 1468.379228 1374.031818 804.1258657 852.8013375 1520.013461 1545.812914 1.019668761 0.797003244 1.03852816 1.119739774 0.949907466 0.888873295 0.520196111 0.551684702 0.983310107 1 10.59415001 -4.85375221 3.008717759 0.999291057 0.523743218 0.832657789 0.079303121 0.06707433 1.194242262 0.011155112 0.042651554 1.40E-05 4.85375221 -0.475547838 GLAPEVADR ddPTM_HeLa_Curcumin_4h_R1 1 GLAPEVADR 9 0 B4E1C5;B4DDD8;B3KWE1;P12081-3;P12081-2;P12081-4;P12081;E7ETE2;D6RJE6;B4DQ67;D6RB22;A0A2R8Y6I1;A0A2R8Y3N3;A0A2R8Y5P7;P49590-2;P49590 B4E1C5 HARS;HARS2 "Histidine--tRNA ligase, cytoplasmic;Probable histidine--tRNA ligase, mitochondrial" 0 0 136.27 0.00026045 3834600 1772.5 1514.6 1882.6 1767 2155 2865 2031.7 1852.6 2354.2 1938.1 FALSE FALSE TRUE 1632.204755 1645.515275 1952.370812 1759.688622 2129.303032 2270.766705 2088.704034 2417.449212 2095.95015 2005.448831 0.813885016 0.820522194 0.973533098 0.877453763 1.061758844 1.132298501 1.041514499 1.205440485 1.045127713 1 10.96970944 -5.645861153 3.987789495 0.905355792 1.115525608 0.573742872 0.079900515 0.123712651 3.629182901 0.012402107 0.025635481 2.26E-06 5.645861153 0.210169816 GLDDDRGPWR ddPTM_HeLa_Curcumin_4h_R1 2 GLDDDRGPWR 10 1 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 ; ; 112.11 0.0057772 40104000 7441.5 6786.8 6524.4 7154.3 7256.3 8286.8 6190.1 6757.1 7299.1 6858.8 FALSE FALSE TRUE 6852.497423 7373.420751 6766.200003 7124.697402 7169.773362 6568.024269 6363.777546 8817.308684 6498.406991 7097.142789 0.965529034 1.038928054 0.953369575 1.003882494 1.010233776 0.925446262 0.896667537 1.242374424 0.915637065 1 12.79302262 -4.249988845 24.93411332 0.979949432 1.242374584 0.765992085 0.045085951 560.2256651 1219897.107 0.005481734 0.115922377 5.62E-05 4.249988845 0.262425153 GLDDSTGGT(ph)PLTPAAR ddPTM_HeLa_Curcumin_4h_R1 2 GLDDSTGGTPLTPAAR 16 0 I3L533;I3L2R9;Q9NXR1;Q9NXR1-1;I3L2R3;I3L2T8;I3L522 I3L533 NDE1 Nuclear distribution protein nudE homolog 1 1 0 GLDDS(0.099)T(0.099)GGT(0.456)PLT(0.345)PAAR;GLDDS(0.109)T(0.158)GGT(0.574)PLT(0.158)PAAR ; 121.42 0.0024678 17533900 5341.7 4029 4636.4 4309.9 4989.8 6915.7 5152 3213.3 5489.8 4816.7 TRUE FALSE FALSE 4918.898808 4377.248807 4808.229063 4292.066776 4930.299894 5481.305864 5296.551254 4193.020378 4887.582675 4984.079966 0.986922128 0.878246103 0.964717479 0.861155279 0.989209629 1.099762825 1.062693875 0.841282725 0.980638896 1 12.2831115 -3.20933133 13.50884854 0.979868717 0.9726889 0 0.081014284 0 0 0.010422871 0 0.000617545 3.20933133 -0.007179817 GLDDTEEPS(ph)PPEDK ddPTM_HeLa_Curcumin_4h_R1 2 GLDDTEEPSPPEDK 14 0 O94806;O94806-2 O94806 PRKD3 Serine/threonine-protein kinase D3 1 0 GLDDTEEPS(1)PPEDK;GLDDTEEPS(1)PPEDK ; 272.74 8.03E-51 29531000 10968.3 9008.6 10319.7 10734.5 9080.2 11437.1 11121.1 11327.8 10565.5 9910.8 TRUE FALSE FALSE 10100.14748 9787.263242 10702.15716 10690.08348 8971.924545 9064.916537 11433.12814 14781.59407 9406.491084 10255.19956 0.984880637 0.954370823 1.043583511 1.042406188 0.874865915 0.883933704 1.114861594 1.441375566 0.917241154 1 13.32406795 -4.334112334 3.040407998 0.983046013 1.479446324 0.852473576 0.059918468 0.081257152 1.165366914 0.007950566 0.08761545 4.63E-05 4.334112334 0.496400311 GLDEDETNFLDEVSR ddPTM_HeLa_Curcumin_4h_R1 2 GLDEDETNFLDEVSR 15 0 Q9GZU8;H3BQQ6;H3BTI2;H3BTP8;H3BSY6;H3BP64;H3BUL4;H3BMX9;H3BU93 Q9GZU8 FAM192A Protein FAM192A 0 0 ; ; 257.2 2.68E-38 15494800 3463.6 2470.6 2776.2 3151.6 2490.8 3636.1 2783.74 2664.7 3133.1 2825 FALSE FALSE TRUE 3189.452405 2684.147655 2879.088414 3138.559514 2461.098837 2881.931873 2861.844252 3477.154763 2789.406769 2923.16854 1.091094257 0.91823226 0.98492043 1.073684077 0.841928477 0.985893161 0.979021296 1.189515663 0.954240828 1 11.5133173 -7.280382607 24.92464396 1.043016729 0.991732051 0 0.092716196 1739.119593 2288250.311 0.015055902 0.017233973 5.24E-08 7.280382607 -0.051284678 GLDEEATPGT(ph)PGDPARPPASK ddPTM_HeLa_Curcumin_4h_R1 2 GLDEEATPGTPGDPARPPASK 21 1 Q7Z7A3 Q7Z7A3 CTU1 Cytoplasmic tRNA 2-thiolation protein 1 1 0 GLDEEAT(0.009)PGT(0.972)PGDPARPPAS(0.019)K;GLDEEATPGT(1)PGDPARPPASK ; 103.94 6.07E-05 27797400 4027.9 3054.2 3633 3320.7 3801.6 5916.1 4863.6 3401.4 3463.6 2802.4 TRUE FALSE FALSE 3709.087465 3318.191439 3767.642176 3306.959823 3756.268403 4689.034172 5000.059526 4438.471202 3083.651746 2899.783191 1.279091304 1.144289493 1.299284094 1.140416233 1.29536181 1.617029227 1.724287368 1.530621743 1.06340769 1 11.50172932 -1 0.1780051 1.002871745 3.957977468 0.747306303 0.115615914 22.59676462 0.243801803 0.168812919 18.1131852 0.1 1 2.955105723 GLDIESYDS(ph)LERPLR ddPTM_HeLa_Curcumin_4h_R1 1 GLDIESYDSLERPLR 15 1 Q9H792 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 0 GLDIES(0.007)YDS(0.993)LERPLR 74.793 0.0098163 1713200 992.04 946.52 815.15 1045.6 1218.1 1105.6 1011.1 599.85 1180.5 767.57 TRUE FALSE FALSE 913.5189872 1028.332971 845.3601761 1041.273584 1203.574953 876.2860973 1039.468745 782.7415036 1051.002103 794.2430004 1.150175685 1.294733439 1.064359618 1.311026454 1.515373699 1.103297224 1.308754052 0.98551892 1.323275248 1 9.63343666 -8.197489681 0.663538798 1.011137009 1.238673643 0 0.17294771 0.621145919 0.602502739 0.061983628 0.035870776 6.35E-09 8.197489681 0.227536633 LQLS(ph)DEESVFEEALMSPDTR ddPTM_HeLa_Curcumin_4h_R1 1 LQLSDEESVFEEALMSPDTR 20 0 G5E9V3;E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;A0A1W2PQ63;E9PGF6 G5E9V3 PHLDB2 Pleckstrin homology-like domain family B member 2 1 0 LQLS(0.947)DEES(0.053)VFEEALMSPDTR 65.387 0.0055962 10195000 346.39 292.3 218.79 302.22 269.76 410.98 147.41 55.118 402.94 236.85 TRUE FALSE FALSE 318.972866 317.5651095 226.8985499 300.9694937 266.5432882 325.7381153 151.5459279 71.92322447 358.7384901 245.0805199 1.301502323 1.295758266 0.92581226 1.228043314 1.087574354 1.329106514 0.618351585 0.293467733 1.463757667 1 7.937112006 -4.594582171 4.095068174 1.152260705 0.352626281 0.775211272 0.163020633 0.064342661 2.045098907 0.020718438 0.092339507 2.54E-05 4.594582171 -0.799634424 down GLDIPEVDWIVQYDPPDDPKEYIHR ddPTM_HeLa_Curcumin_4h_R1 1 GLDIPEVDWIVQYDPPDDPKEYIHR 25 1 H7C452;Q9NVP1 H7C452 DDX18 ATP-dependent RNA helicase DDX18 0 0 97.689 3.95E-06 7585000 1489.1 954.92 1434 1594.9 1249.8 1985.8 1226.8 1049.9 1644.3 1526.7 FALSE FALSE TRUE 1371.236164 1037.45903 1487.145301 1588.300726 1234.896951 1573.922695 1261.220706 1370.009677 1463.924404 1579.752711 0.868006843 0.656722424 0.94137854 1.005410983 0.781702695 0.996309539 0.798365907 0.867230464 0.926679469 1 10.62548303 -8.97196514 0.989985808 0.993513848 0.866640058 0.118362166 0.101090956 0.615516469 1.165240722 0.048327281 0.01848981 1.07E-09 8.97196514 -0.126873791 GLDNTEFQGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GLDNTEFQGKR 11 1 E9PB51;Q9BWF3;Q9BQ04 E9PB51 RBM4;RBM4B RNA-binding protein 4;RNA-binding protein 4B 0 1 ; GLDNTEFQGK(1)R;GLDNTEFQGK(1)R 100.69 0.0032993 4900400 1336.12 1293.26 1491.98 1548.93 1408.22 1386.31 1295.67 985.48 1994.85 1440.32 FALSE TRUE FALSE 1230.364692 1405.043632 1547.274091 1542.520938 1391.427896 1098.773679 1332.023013 1285.948315 1776.019946 1490.371013 0.825542554 0.942747557 1.038180479 1.034991237 0.933611755 0.737248423 0.89375263 0.862837712 1.191662969 1 10.5414558 -5.463803738 24.31523072 0.937141118 0.837177234 0.221798918 0.107166639 237.2485992 97650.63276 0.012880929 0.028802562 3.44E-06 5.463803738 -0.099963884 GLDS(ph)GAETEEEKDTWEEK ddPTM_HeLa_Curcumin_4h_R1 1 GLDSGAETEEEKDTWEEK 18 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 GLDS(0.998)GAET(0.002)EEEKDTWEEK 110.61 0.00031639 19063000 2368.5 1548.4 1533.2 1661.5 1936.7 1609.2 1375.9 1369.8 1849.5 2141.1 TRUE FALSE FALSE 2181.030726 1682.236796 1590.021741 1654.625153 1913.606117 1275.433781 1414.504051 1787.445714 1646.614477 2215.503066 0.984440401 0.759302401 0.717679775 0.746839478 0.863734358 0.575685857 0.638457275 0.806789998 0.743223741 1 11.11341861 -7.228886339 3.659169869 0.993976406 0.722437629 0.28251185 0.109245138 0.086257576 2.4496065 0.012842275 0.01544468 5.90E-08 7.228886339 -0.271538777 GLDSSSTAPS(ph)ALGER ddPTM_HeLa_Curcumin_4h_R1 1 GLDSSSTAPSALGER 15 0 J3KTM2;O15534-4;O15534;J3QL46 J3KTM2 PER1 Period circadian protein homolog 1 1 0 GLDSSS(0.002)T(0.008)APS(0.99)ALGER 113.43 0.0018676 14867000 2810.5 1984.2 2317.6 2531.1 1935.1 3124.9 1937.9 1509.9 2969.3 2685.7 TRUE FALSE FALSE 2588.045959 2155.705407 2403.492295 2520.626979 1912.025196 2476.760515 1992.272258 1970.261559 2643.575219 2779.027875 0.931277438 0.775704852 0.864868005 0.907017523 0.688019438 0.8912327 0.716895385 0.708975098 0.951258979 1 11.44036459 -4.932165638 0.155928161 1.076184222 0.467295052 0.572270204 0.069668138 7.32407184 0.256639191 0.203739211 0.973245497 1.17E-05 4.932165638 -0.608889171 GLDVEDVK ddPTM_HeLa_Curcumin_4h_R1 2 GLDVEDVK 8 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;P17844-2;P17844;J3KTA4 A0A1X7SBZ2;P17844-2 DDX17;DDX5 Probable ATP-dependent RNA helicase DDX17;Probable ATP-dependent RNA helicase DDX5 0 0 ; ; 109.21 0.0069383 16988300 18360.8 13987.7 15346.1 16031.1 16288.2 20551 15636.5 14667.8 17203.5 15158 FALSE FALSE TRUE 16907.52331 15196.73446 15914.83997 15964.76756 16093.97385 16288.49094 16075.21811 19139.9447 15316.31909 15684.73937 1.077960105 0.968886642 1.014670349 1.017853544 1.026091252 1.03849293 1.024895456 1.220290898 0.976510908 1 13.93707394 -4.260686346 24.95414325 1.02903245 1.220290959 0.781659171 0.031716453 23.294029 771771.7953 0.00469849 0.037539749 5.49E-05 4.260686346 0.191258509 GLEELVK ddPTM_HeLa_Curcumin_4h_R1 1 GLEELVK 7 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 111.04 0.013217 7913400 4239.4 3420.3 3497.2 4708.3 4144.6 4273.8 3219 3590.6 4217.9 3929.3 FALSE FALSE TRUE 3903.847017 3715.935491 3626.809308 4688.818302 4095.178352 3387.365704 3309.316477 4685.357411 3755.206923 4065.842883 0.96015688 0.913939766 0.892019051 1.153221715 1.007215102 0.833127546 0.813931225 1.152370504 0.923598632 1 11.98933875 -6.490158861 0.005246399 1.930755468 8.82E-08 0 0.112681709 33803.27709 84.52557602 15386.56006 15717.31621 3.23E-07 6.490158861 -1.93075538 GLEGERPAR ddPTM_HeLa_Curcumin_4h_R1 1 GLEGERPAR 9 1 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6;A0A2R8Y6L3 P46783 RPS10;RPS10-NUDT3 40S ribosomal protein S10 0 0 88.177 0.018808 6396700 1383.8 1152 1234.3 1449.7 1482.9 1865.5 1370.9 1388.1 1642.7 1287.7 FALSE FALSE TRUE 1274.27077 1251.573747 1280.044244 1443.701526 1465.217386 1478.574271 1409.363764 1811.3253 1462.49992 1332.447479 0.95633846 0.939304375 0.960671444 1.083496009 1.099643632 1.109667957 1.057725566 1.359397146 1.097604178 1 10.37986295 -1 0.484998836 0.977380041 10.74247221 0.682652542 0.065215755 29.34569922 0.292566332 0.011031765 291.6772174 0.1 1 9.765092164 GLEGNANS(ph)PAHLR ddPTM_HeLa_Curcumin_4h_R1 2 GLEGNANSPAHLR 13 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 GLEGNANS(1)PAHLR;GLEGNANS(1)PAHLR ; 119.96 0.0011861 43184000 8121.3 6667.6 7651.2 7543.2 8391.3 9803.1 8187.3 4223.1 7637.8 5753.4 TRUE FALSE FALSE 7478.490535 7243.917634 7934.760203 7511.988237 8291.239228 7769.826556 8417.013603 5510.703749 6799.952449 5953.330222 1.256186077 1.216784113 1.332827158 1.261812793 1.392706085 1.305122724 1.413832811 0.92565061 1.142209855 1 12.53948121 -9.015285138 0.59595316 0.975033734 1.281892227 0.214820032 0.134767391 0.750635948 0.440217616 0.121325039 0.02846178 9.65E-10 9.015285138 0.306858493 GLEKES(ph)HNSR ddPTM_HeLa_Curcumin_4h_R1 2 GLEKESHNSR 10 1 P23229-9 P23229-9 ITGA6 Integrin alpha-6;Integrin alpha-6 heavy chain;Integrin alpha-6 light chain;Processed integrin alpha-6 1 0 GLEKES(1)HNSR;GLEKES(0.999)HNS(0.001)R ; 85.676 0.010863 33169000 7236.8 5410.2 5941.8 5990.9 7225 5552.7 4101.8 5034 6821 6325.9 TRUE FALSE FALSE 6663.999644 5877.833581 6162.008335 5966.111243 7138.846594 4401.007428 4216.885469 6568.843426 6072.753365 6545.724554 1.01806906 0.89796531 0.941379107 0.911451619 1.090612129 0.6723484 0.644219816 1.003531904 0.927743493 1 12.67633718 -5.259910357 24.99615868 0.992312762 0.760452015 0.404613076 0.106277311 79.73710741 1303509.92 0.013930421 0.03353658 5.50E-06 5.259910357 -0.231860747 GLEPS(ph)PAAVAALPPEVR ddPTM_HeLa_Curcumin_4h_R1 3 GLEPSPAAVAALPPEVR 17 0 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 1 0 GLEPS(1)PAAVAALPPEVR;GLEPS(1)PAAVAALPPEVR;GLEPS(1)PAAVAALPPEVR ;; 170.79 6.09E-05 16652700 5724.5 4962.01 4809.58 5081.43 4952.71 8404.5 7046.2 3564.99 5826 5089.49 TRUE FALSE FALSE 5271.399785 5390.904034 4987.827266 5060.404389 4893.652168 6661.311962 7243.897408 4651.93904 5186.902376 5266.349399 1.000958992 1.023651039 0.947112865 0.960894161 0.92923044 1.264882266 1.37550642 0.883332777 0.984914213 1 12.36258753 -5.262882276 24.99936306 0.990992027 1.194667084 0.355752394 0.119369969 92.98801225 1611110.337 0.01537568 0.036185551 5.46E-06 5.262882276 0.203675058 GLESTTLADKDGEIYCK ddPTM_HeLa_Curcumin_4h_R1 2 GLESTTLADKDGEIYCK 17 1 E9PP21;P21291;E9PND2 E9PP21 CSRP1 Cysteine and glycine-rich protein 1 0 0 ; ; 140.03 3.76E-06 5072100 4488.4 3986.9 3660.4 4164.1 3673.7 4692.6 3219.8 3829.1 4279 3640.5 FALSE FALSE TRUE 4133.138404 4331.509871 3796.057644 4146.870058 3629.893527 3719.301863 3310.138922 4996.574963 3809.604406 3767.007104 1.097194215 1.149854447 1.007711836 1.100839458 0.963601455 0.987336036 0.878718524 1.326404444 1.011307996 1 11.87920304 -5.779569465 24.9552865 1.05588081 1.023873948 0.000670776 0.117282298 1039.227927 1430450.19 0.016324345 0.029629273 1.66E-06 5.779569465 -0.032006861 GLEYLYLNVHDEDRDDQTR ddPTM_HeLa_Curcumin_4h_R1 3 GLEYLYLNVHDEDRDDQTR 19 1 Q9Y6G9;C9JGM7;C9JLW1 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 0 0 ;; ;; 107.63 0.00026882 58367300 12439.5 10601.5 9747.2 10609.4 10431 13391.6 10503.6 9540.1 12160.2 10946.9 FALSE FALSE TRUE 11454.90045 11517.84642 10108.43981 10565.50111 10306.61714 10614.03121 10798.30275 12448.83257 10826.25648 11327.30396 1.011264506 1.016821519 0.892395917 0.932746323 0.90989146 0.937030669 0.953298577 1.099011081 0.955766396 1 13.4675169 -6.804510622 24.99993396 1.006330664 0.950276636 0.108678609 0.055069242 160.4320264 93119.35203 0.008314541 0.010927488 1.57E-07 6.804510622 -0.056054028 GLEYLYLSVHDEDRDDHTR ddPTM_HeLa_Curcumin_4h_R1 1 GLEYLYLSVHDEDRDDHTR 19 1 O43237 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 0 0 61.127 0.0049209 3431200 1789.3 1935.4 1409.4 1365.5 2271 3849.5 2086.6 1579.5 2331 1672.2 FALSE FALSE TRUE 1647.675017 2102.687352 1461.633604 1359.849923 2243.919808 3051.070307 2145.14438 2061.082279 2075.295132 1730.308826 0.952243318 1.215209286 0.844724122 0.785900125 1.296831973 1.763309683 1.23974654 1.191164403 1.199378458 1 10.75681384 -5.609064407 6.372637017 0.974526292 1.405680714 0.480730289 0.190858584 0.112269564 6.750195627 0.025051353 0.050483961 2.46E-06 5.609064407 0.431154422 GLFDDEDEESDLFTEAPQDR ddPTM_HeLa_Curcumin_4h_R1 3 GLFDDEDEESDLFTEAPQDR 20 0 Q641Q2;F8W7U3;E7ESD2;Q641Q2-2;A0A087WYF6 Q641Q2 FAM21A WASH complex subunit FAM21A 0 0 ;; ;; 334.72 1.60E-134 26012600 6280.1 4853.9 5006.2 5591.1 5766.2 7002.9 5462.5 5472.6 6354.1 5913.9 FALSE FALSE TRUE 5783.023458 5273.449487 5191.734176 5567.96551 5697.441831 5550.419601 5615.763048 7141.170547 5657.071127 6119.407585 0.945029952 0.861758171 0.848404703 0.909886363 0.931044673 0.907019107 0.917697174 1.166970895 0.924447514 1 12.57917628 -4.2573897 24.62361754 0.943268044 1.166971004 0.690133165 0.0473818 191.8663229 1166562.859 0.008377755 0.085322968 5.53E-05 4.2573897 0.22370296 GLFDDEDEESDLFTEASQDR ddPTM_HeLa_Curcumin_4h_R1 2 GLFDDEDEESDLFTEASQDR 20 0 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1-5 A0A0A0MR88 FAM21C WASH complex subunit FAM21C 0 0 ; ; 302.2 1.06E-97 13046400 2834.47 2810.87 2477 2662.7 2372.36 3653.8 2873.6 2036.55 3735.8 3004.2 FALSE FALSE TRUE 2610.118709 3053.829078 2568.799799 2651.682453 2344.071156 2895.960693 2954.225482 2657.48472 3325.992087 3108.595726 0.839645595 0.98238219 0.82635377 0.85301618 0.754061114 0.931597721 0.950340843 0.854882704 1.069933944 1 11.60204729 -9.421481064 0.899754037 1.008491331 0.872422286 0.459594906 0.0671411 0.613568564 0.794347554 0.059909597 0.011783809 3.79E-10 9.421481064 -0.136069045 GLFDEEMNEILTDPSDDTK ddPTM_HeLa_Curcumin_4h_R1 1 GLFDEEMNEILTDPSDDTK 19 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 103.99 0.0027538 5522800 3763.8 3643.7 4008.6 3715.2 4448.3 5145.6 4278.9 3585.2 4308 4242.2 FALSE FALSE TRUE 3465.891258 3958.645192 4157.162242 3699.827487 4395.256928 4078.344557 4398.954418 4678.310976 3835.423178 4389.616134 0.78956591 0.901820358 0.947044597 0.842859005 1.001285031 0.929089112 1.002127358 1.065767674 0.873749107 1 12.09987907 -4.340143135 0.793151922 0.900147872 1.1487532 0.443856491 0.060076881 2.254689385 1.08863025 0.013583512 0.48081037 4.57E-05 4.340143135 0.248605328 GLFDEYGSK ddPTM_HeLa_Curcumin_4h_R1 2 GLFDEYGSK 9 0 P14625;Q58FF3 P14625;Q58FF3 HSP90B1;HSP90B2P Endoplasmin;Putative endoplasmin-like protein 0 0 ; ; 141.48 1.51E-05 6997300 7478.1 5914.8 7464.4 7114.7 6918.2 8619.8 5929.5 4374.7 6834.4 6071.8 FALSE FALSE TRUE 6886.200494 6426.048956 7741.03723 7085.261257 6835.704983 6831.956315 6095.865812 5708.525891 6084.683419 6282.794598 1.096041003 1.022801057 1.232100956 1.127724478 1.088003893 1.087407237 0.97024751 0.908596613 0.968467666 1 12.6171907 -4.598773412 3.536115476 1.069135356 0.917928595 0.392943031 0.06986563 0.188914283 4.499308252 0.010122787 0.049045263 2.52E-05 4.598773412 -0.151206761 GLFEEAAK ddPTM_HeLa_Curcumin_4h_R1 1 GLFEEAAK 8 0 H3BVG0;Q8N1F7;Q8N1F7-2;H3BVE2 H3BVG0 NUP93 Nuclear pore complex protein Nup93 0 0 98.523 0.014768 1470100 1519 949.84 1236.5 1152.9 1086.3 1276.1 1120.1 1126.7 997.48 1205.3 FALSE FALSE TRUE 1398.769547 1031.939937 1282.325778 1148.129605 1073.346582 1011.422475 1151.526991 1470.225643 888.0589396 1247.184085 1.121542171 0.827415896 1.028176829 0.920577498 0.860616003 0.810964867 0.923301544 1.178836116 0.712051212 1 10.28445871 -7.272478044 24.95743586 1.057394913 0.930511652 0 0.150940751 767.7273749 1735759.522 0.01825254 0.020980434 5.34E-08 7.272478044 -0.126883261 GLFIIDDK ddPTM_HeLa_Curcumin_4h_R1 2 GLFIIDDK 8 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5;H7C3T4;Q13162 A0A0A0MSI0;Q13162 PRDX1;PRDX4 Peroxiredoxin-1;Peroxiredoxin-4 0 0 ; ; 107.66 0.0077991 71566000 3187.3 2551.5 3849.2 3264.7 2224 2696.7 2646.2 2116.4 2125.1 1106.62 FALSE FALSE TRUE 2935.021842 2772.040291 3991.854738 3251.191536 2197.480253 2137.374022 2720.44525 2761.680617 1891.981847 1145.074963 2.563170044 2.420837396 3.486107782 2.839282704 1.919071086 1.866579998 2.375779175 2.411790239 1.652277718 1 10.16122633 -9.131643067 0.838726616 0.977373564 2.485630959 0.471709604 0.472199988 0.362295915 0.450848555 0.343388965 0.094350982 7.39E-10 9.131643067 1.508257395 GLFIIDDKGILR ddPTM_HeLa_Curcumin_4h_R1 1 GLFIIDDKGILR 12 1 A0A0A0MSI0;Q06830;A0A0A0MRQ5;H7C3T4;Q13162 A0A0A0MSI0;Q13162 PRDX1;PRDX4 Peroxiredoxin-1;Peroxiredoxin-4 0 0 100.82 0.0076243 7269000 4488.8 2736.6 2938.3 3331.4 2352.8 3588.3 2481.2 2873.6 4599.9 4537.4 FALSE FALSE TRUE 4133.506743 2973.13951 3047.195983 3317.61555 2324.744397 2844.046132 2550.815794 3749.747412 4095.302478 4695.074312 0.880392187 0.633246529 0.649019756 0.706616196 0.495145389 0.605751037 0.543296149 0.798655604 0.872255092 1 12.19693228 -7.394833414 1.298792645 0.963519474 0.616336225 0.675760187 0.088406967 0.13160052 0.433163082 0.01679499 0.018825513 4.03E-08 7.394833414 -0.347183249 GLFIIDGK ddPTM_HeLa_Curcumin_4h_R1 2 GLFIIDGK 8 0 P32119 P32119 PRDX2 Peroxiredoxin-2 0 0 ; ; 114.6 0.0039457 12264100 16287.7 13185.8 15168.5 15079.8 14317.1 16394.6 13330.9 12627.7 12857.2 12502.3 FALSE FALSE TRUE 14998.51136 14325.5218 15730.65795 15017.40378 14146.37793 12994.17515 13704.92918 16477.8276 11446.79733 12936.75399 1.159372078 1.107350561 1.215966382 1.160832446 1.093502894 1.004438606 1.059379283 1.273721956 0.884827626 1 13.65918805 -9.326313963 0.984808881 0.997893496 1.130649772 0.428908874 0.082043912 0.569868905 0.964667466 0.054399655 0.013494606 4.72E-10 9.326313963 0.132756275 GLFITIHDR ddPTM_HeLa_Curcumin_4h_R1 2 GLFITIHDR 9 0 P48163;P48163-2 P48163 ME1 NADP-dependent malic enzyme 0 0 ; ; 92.062 0.0052018 2063500 1598.78 1182.65 1465.79 1127.64 1649.41 1767.75 1520.49 1779.49 1374.72 1412.44 FALSE FALSE TRUE 1472.234876 1284.872996 1520.113467 1122.974124 1629.741863 1401.098723 1563.150857 2322.048309 1223.916655 1461.522185 1.007329818 0.87913342 1.040089218 0.768359274 1.115098956 0.958657171 1.069536182 1.58878759 0.837425985 1 10.51325601 -4.258258704 3.199737301 0.986238372 1.678849859 0.775900168 0.101069853 0.100834454 1.594875379 0.01121283 0.174164173 5.52E-05 4.258258704 0.692611486 GLFQDEDS(ph)CSDCSYR ddPTM_HeLa_Curcumin_4h_R1 2 GLFQDEDSCSDCSYR 15 0 Q8NEM2 Q8NEM2 SHCBP1 SHC SH2 domain-binding protein 1 1 0 GLFQDEDS(0.939)CS(0.06)DCS(0.001)YR;GLFQDEDS(0.977)CS(0.009)DCS(0.015)YR ; 150.92 0.00043513 90893000 3909.8 4005.4 3338.48 4061 3243.32 4634.2 3360.15 2189.42 3876.4 3863.96 TRUE FALSE FALSE 3600.335204 4351.608928 3462.207006 4044.196658 3204.645527 3673.014682 3454.426766 2856.964079 3451.168618 3998.232322 0.900481741 1.08838321 0.865934425 1.011496164 0.801515587 0.918659644 0.863988505 0.714556796 0.863173608 1 11.96514659 -2.878831278 0.477910576 0.961833442 6.99E-13 0.417255148 0.078628011 9.0324359 0.511373773 0.014594692 6.600352894 0.001321809 2.878831278 -0.961833442 GLFQDEDSCS(ph)DCSYR ddPTM_HeLa_Curcumin_4h_R1 2 GLFQDEDSCSDCSYR 15 0 Q8NEM2 Q8NEM2 SHCBP1 SHC SH2 domain-binding protein 1 1 0 GLFQDEDS(0.029)CS(0.955)DCS(0.015)YR;GLFQDEDS(0.481)CS(0.519)DCSYR ; 233.48 3.76E-21 17607300 4057.9 3479.9 3746.6 3679.9 3560.2 4435.9 3138.5 2369.28 4437.9 3859.8 TRUE FALSE FALSE 3736.712933 3780.68705 3885.452292 3664.673549 3517.74694 3515.844337 3226.557863 3091.662565 3951.073473 3993.927763 0.935598527 0.946608771 0.972839902 0.9175613 0.880773802 0.880297428 0.807865854 0.774090757 0.989270139 1 11.96359252 -1.961708017 0.274686073 0.985569767 7.72E-15 0.937012671 0.017926902 5.82681668 0.118811725 0.010279935 2.496541252 0.010921744 1.961708017 -0.985569767 GLFS(ph)DEEDSEDLFSSQSASK ddPTM_HeLa_Curcumin_4h_R1 4 GLFSDEEDSEDLFSSQSASK 20 0 Q641Q2;F8W7U3;E7ESD2;Q641Q2-2;A0A087WYF6 Q641Q2 FAM21A WASH complex subunit FAM21A 1 0 GLFS(1)DEEDSEDLFSSQSASK;GLFS(1)DEEDSEDLFSSQSASK;GLFS(1)DEEDSEDLFSSQSASK;GLFS(1)DEEDSEDLFSSQSASK ;;; 175.02 3.18E-07 44000400 10828.7 8306.6 9079.3 10177.7 9909.9 11619.4 8729.6 6988 12027.1 9298.9 TRUE FALSE FALSE 9971.596969 9024.585491 9415.786845 10135.58737 9791.730915 9209.405462 8974.529081 9118.609031 10707.75722 9622.036083 1.036329201 0.937908091 0.978564907 1.053372414 1.017636063 0.957116081 0.932705823 0.947679779 1.112836943 1 13.23212649 -5.161169099 4.072769076 1.011261759 0.941354856 0.361988881 0.044159444 0.15792213 4.616324131 0.004668024 0.012637249 6.90E-06 5.161169099 -0.069906903 GLFS(ph)DEEDSEDLFSSQSASNLK ddPTM_HeLa_Curcumin_4h_R1 3 GLFSDEEDSEDLFSSQSASNLK 22 0 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1-5 A0A0A0MR88 FAM21C WASH complex subunit FAM21C 1 0 GLFS(0.995)DEEDS(0.005)EDLFSSQSASNLK;GLFS(1)DEEDSEDLFSSQSASNLK;GLFS(0.999)DEEDS(0.001)EDLFSSQSASNLK ;; 181.81 1.91E-10 28422400 6714.8 5063.9 5740.5 6001.6 6029 8113.5 5973.4 4313.2 7073.6 6097.7 TRUE FALSE FALSE 6183.316495 5501.600952 5953.24798 5976.766969 5957.108113 6430.668642 6140.997527 5628.274824 6297.643777 6309.594621 0.979986333 0.871942063 0.943523053 0.947250549 0.944134841 1.019188875 0.973279251 0.892018452 0.998105925 1 12.6233316 -7.496723201 19.03182166 0.991171064 0.944761312 0.27502656 0.03817244 19.84574333 14442.16645 0.00679246 0.007372092 3.19E-08 7.496723201 -0.046409752 GLGDCLVK ddPTM_HeLa_Curcumin_4h_R1 1 GLGDCLVK 8 0 P12236;P05141 P12236 SLC25A6;SLC25A5 "ADP/ATP translocase 3;ADP/ATP translocase 3, N-terminally processed;ADP/ATP translocase 2;ADP/ATP translocase 2, N-terminally processed" 0 0 94.662 0.018299 1192500 2777.1 2646.8 2405.1 3173.7 2716 4541.7 3334.6 3566.5 4105.7 3053.6 FALSE FALSE TRUE 2557.289605 2875.577598 2494.235122 3160.56807 2683.613474 3599.700224 3428.159901 4653.909432 3655.314982 3159.712373 0.80934253 0.910075747 0.789386763 1.000270815 0.849322077 1.139249337 1.084959483 1.472890214 1.156850545 1 11.62557752 -3.396293663 0.776732995 0.900741111 3.108879335 0.647191483 0.116065128 2.828111203 0.461953013 0.015014744 7.453999896 0.000401519 3.396293663 2.208138224 GLGHPPS(ph)SPLLKK ddPTM_HeLa_Curcumin_4h_R1 1 GLGHPPSSPLLKK 13 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 0 GLGHPPS(0.916)S(0.084)PLLKK 109.07 0.0019906 41133000 3802.2 3074.9 3015.6 3212.4 3262.4 5010.2 4574.5 3458.9 4116 3594.8 TRUE FALSE FALSE 3501.251858 3340.680655 3127.360789 3199.10794 3223.498011 3971.028043 4702.848158 4513.502687 3664.485098 3719.719032 0.941267829 0.898100267 0.840751885 0.860040211 0.866597176 1.067561289 1.264301986 1.213398821 0.985151047 1 11.86097794 -4.949223199 3.687828208 0.941396338 1.236802776 0.838089796 0.056385421 0.080755348 2.270669135 0.009829861 0.032128726 1.12E-05 4.949223199 0.295406438 GLGHPPSS(ph)PLLK ddPTM_HeLa_Curcumin_4h_R1 2 GLGHPPSSPLLK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 0 GLGHPPS(0.207)S(0.793)PLLK;GLGHPPS(0.233)S(0.767)PLLK ; 124.6 0.0023951 99778000 9445.5 8414.5 7521.3 8743.8 8467.8 12960.4 11223.2 11023.5 10484.8 7966.9 TRUE FALSE FALSE 8697.878708 9141.811886 7800.045994 8707.620472 8366.827016 10272.26695 11538.09279 14384.5144 9334.643672 8243.749182 1.055087742 1.108938625 0.946177015 1.056269457 1.014929837 1.24606738 1.399617156 1.74489957 1.132329898 1 13.0090849 -4.381240549 1.084619877 1.02572892 2.004149229 0.934361724 0.058610312 0.189731712 0.202782776 0.007192926 0.20158329 4.16E-05 4.381240549 0.978420309 GLGK(ac)GGAK ddPTM_HeLa_Curcumin_4h_R1 2 GLGKGGAK 8 1 P62805;Q99525 P62805 HIST1H4A;HIST1H4G Histone H4;Histone H4-like protein type G 0 1 ; GLGK(1)GGAK;GLGK(1)GGAK 101.28 0.012027 31946000 10601.2 8184.4 10584.2 9409.1 9973.7 15213.6 11088.5 4557.5 9136 9590.6 FALSE TRUE FALSE 9762.103834 8891.823067 10976.45976 9370.167637 9854.770142 12058.12787 11399.61347 5947.06077 8133.803657 9923.872636 0.983699025 0.896003344 1.106066166 0.944204746 0.993036741 1.215062739 1.148706144 0.599268147 0.819619916 1 13.2766875 -4.249504165 24.82946133 1.012836596 0.599267872 0.550346816 0.11186892 846.2388401 1760441.131 0.01309992 0.288302242 5.63E-05 4.249504165 -0.413568725 GLGK(ac)GGAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GLGKGGAKR 9 2 P62805 P62805 HIST1H4A Histone H4 0 2 ; GLGK(1)GGAK(1)R;GLGK(1)GGAK(1)R 148.99 1.53E-07 2357600000 13185 7322 12306.5 16697.9 10807.3 25444.1 17002.4 7686.3 14888.2 12160.8 FALSE TRUE FALSE 12141.39334 7954.881054 12762.58972 16628.80851 10678.43001 20166.70685 17479.44158 10029.81749 13255.00171 12583.38689 0.964874834 0.632173287 1.014241223 1.321489091 0.848613342 1.602645378 1.389088783 0.797068196 1.053373135 1 13.61923266 -6.431329432 6.551335834 0.950636581 1.204772565 0.215738968 0.247761995 0.302228313 18.27637251 0.036417324 0.055682912 3.70E-07 6.431329432 0.254135984 NASLSQS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 NASLSQSPR 9 0 C9J1X0;A4D1P6-3;A4D1P6-2;A4D1P6 C9J1X0 WDR91 WD repeat-containing protein 91 1 0 NASLSQS(1)PR;NASLSQS(1)PR;NASLS(0.006)QS(0.994)PR ;; 140.78 0.0023334 136946800 8235 7281.7 7466 7391.7 7384.5 7622 4907.1 2684.87 9311.4 7297.6 TRUE FALSE FALSE 7583.19106 7911.097701 7742.696528 7361.115104 7296.44466 6041.111282 5044.780019 3503.474503 8289.962716 7551.191057 1.004237743 1.047662235 1.025360962 0.974828348 0.966264077 0.800020982 0.668077391 0.463963165 1.097835117 1 12.8824885 -4.592581429 1.018186095 1.008488232 0.344299839 0.966250046 0.034914543 0.08929547 0.101481803 0.003328062 0.05650808 2.56E-05 4.592581429 -0.664188393 down GLGLDDALEPR ddPTM_HeLa_Curcumin_4h_R1 1 GLGLDDALEPR 11 0 Q9Y230;M0R0Z0;A0A1W2PS48;X6R2L4 Q9Y230 RUVBL2 RuvB-like 2 0 0 91.265 0.019715 1672200 761.09 824.66 582.12 750.37 763.2 1006.6 770.06 700.06 975.97 709.31 FALSE FALSE TRUE 700.8489234 895.9399358 603.6938793 747.2651678 754.0993385 797.8198133 791.6658111 913.5050713 868.9085328 733.9584697 0.954889074 1.220695683 0.822517764 1.018130042 1.027441428 1.087009478 1.078624805 1.24462774 1.183866075 1 9.519554622 -1 0.566396822 0.986721958 13.70241498 0.165053253 0.111928765 92.07289445 0.731572141 0.015672892 1438.664838 0.1 1 12.71569302 GLGLGANLTEAQALT(ph)PTGPSR ddPTM_HeLa_Curcumin_4h_R1 2 GLGLGANLTEAQALTPTGPSR 21 0 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 1 0 GLGLGANLT(0.04)EAQALT(0.881)PT(0.079)GPSR;GLGLGANLT(0.24)EAQALT(0.76)PTGPSR ; 178.1 2.71E-09 42579000 5160.1 4640.5 4387.8 4936.8 5385.8 7388.4 7281.9 6781.2 4968.8 4313.2 TRUE FALSE FALSE 4751.67264 5041.604142 4550.415728 4916.37283 5321.577853 5855.962556 7486.210516 8848.756663 4423.735071 4463.083379 1.064661409 1.129623562 1.019567716 1.101564191 1.192354568 1.312088988 1.677362908 1.982655468 0.991183605 1 12.12382504 -4.347731818 0.820314056 1.03620061 2.491798629 0.982867374 0.040975077 0.180916763 0.095157879 0.006714712 0.231709171 4.49E-05 4.347731818 1.45559802 GLGLSK(ac)AYVGQK ddPTM_HeLa_Curcumin_4h_R1 2 GLGLSKAYVGQK 12 1 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 1 ; GLGLSK(1)AYVGQK;GLGLSK(1)AYVGQK 171.92 8.58E-07 7725800 3187.9 2385.6 2567.4 2473.3 2736.3 3482.8 2847.5 2638.1 2862.6 2891.5 FALSE TRUE FALSE 2935.574351 2591.800634 2662.550103 2463.06614 2703.67141 2760.428021 2927.393186 3442.444546 2548.579942 2991.97941 0.981147912 0.866249489 0.889895864 0.823222958 0.903639711 0.922609297 0.978413547 1.150557565 0.851803971 1 11.54688453 -4.270982473 3.770728095 0.952774707 1.169087812 0.4533677 0.066945456 0.200035285 5.438588074 0.010281753 0.11823144 5.36E-05 4.270982473 0.216313105 GLGPPS(ph)PPAPPR ddPTM_HeLa_Curcumin_4h_R1 1 GLGPPSPPAPPR 12 0 Q13425;A0A140TA73;Q13425-2 Q13425 SNTB2 Beta-2-syntrophin 1 0 GLGPPS(1)PPAPPR 109.16 0.0058298 255520000 1961.3 1986.6 1740.5 1968.8 1910.6 2065.1 1517.3 1096.7 1737.6 1661.7 TRUE FALSE FALSE 1806.061035 2158.312852 1805.004461 1960.653627 1887.817343 1636.774982 1559.871354 1431.078781 1546.989627 1719.443951 1.050375055 1.255238852 1.049760569 1.140283535 1.097923164 0.951921102 0.907195232 0.832291614 0.899703434 1 10.74772637 -4.905239574 2.26064815 1.057009433 0.856801039 0.455403807 0.088902197 0.213291543 2.120527037 0.011932059 0.050647692 1.24E-05 4.905239574 -0.200208394 GLGPS(ph)PAGDGPSGSGK ddPTM_HeLa_Curcumin_4h_R1 2 GLGPSPAGDGPSGSGK 16 0 Q92934;F5GYS3;A8MXU7 Q92934 BAD Bcl2-associated agonist of cell death 1 0 GLGPS(0.814)PAGDGPS(0.185)GS(0.001)GK;GLGPS(0.617)PAGDGPS(0.375)GS(0.008)GK ; 119.04 0.00099815 26005000 7073.9 6137 6354 6412.6 5711.8 7975.6 6515 5764 7603.8 6597.1 TRUE FALSE FALSE 6513.993351 6667.454934 6589.48483 6386.06636 5643.690515 6321.370656 6697.793366 7521.417066 6769.682164 6826.348734 0.954242686 0.976723457 0.965301523 0.935502508 0.826750981 0.926025157 0.98116777 1.101821392 0.991698846 1 12.7368984 -9.05286839 0.656315745 1.002956888 0.952765323 0.047233645 0.063757904 2.197992135 1.584912756 0.061250482 0.014828682 8.85E-10 9.05286839 -0.050191565 GLGTDEDS(ph)LIEIICSR ddPTM_HeLa_Curcumin_4h_R1 1 GLGTDEDSLIEIICSR 16 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YNP5;H0YN28;H0YKS4;H0YL33;H0YMM1;H0YNA0;H0YN52;H0YLE2;P07355-2 P07355;P07355-2 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 1 0 GLGTDEDS(1)LIEIICSR 295.71 5.32E-80 23066000 1586.8 1848.1 1532.2 1463.5 1503.4 1887 1563.5 1781.1 2014.3 1460.3 TRUE FALSE FALSE 1461.203106 2007.841529 1588.98468 1457.444425 1485.472937 1495.614929 1607.367602 2324.149191 1793.33633 1511.045316 0.967014748 1.328776515 1.051579766 0.964527277 0.983076365 0.98978827 1.063745465 1.538106876 1.186818364 1 10.56133121 -4.261036347 3.840780791 1.012486282 1.59035781 0.57800642 0.117432069 0.111254011 3.201787352 0.014777542 0.180568319 5.48E-05 4.261036347 0.577871528 GLGTDEDSLIEIICSR ddPTM_HeLa_Curcumin_4h_R1 2 GLGTDEDSLIEIICSR 16 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YNP5;H0YN28;H0YKS4;H0YL33;H0YMM1;H0YNA0;H0YN52;H0YLE2;P07355-2 P07355;P07355-2 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 0 ; ; 246.63 1.26E-29 18110800 2896.2 2020.39 2428.9 3022.4 2381.2 4083.9 2946.7 3039.3 3147.3 2421.1 FALSE FALSE TRUE 2666.962714 2195.023509 2518.917171 3009.89411 2352.805745 3236.853105 3029.376471 3965.968579 2802.049064 2505.233045 1.064556736 0.876175378 1.005462217 1.201442762 0.939156439 1.292036728 1.209219429 1.583073713 1.118478407 1 11.2907291 -1.000007507 0.584365962 1.018342523 32.6453401 0.727124781 0.101906447 47.82861946 0.358976574 0.016026904 1928.637431 0.099998271 1.000007507 31.62699758 GLGTDEDTLIEILAS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 GLGTDEDTLIEILASR 16 0 P04083;Q5T3N1 P04083 ANXA1 Annexin A1;Annexin 1 0 GLGTDEDTLIEILAS(1)R;GLGTDEDTLIEILAS(1)R ; 156.72 0.00029688 22326000 1082.69 1003.98 1139.57 1257.72 1350.7 1543.91 1082.98 1075.46 1542.93 933.54 TRUE FALSE FALSE 996.9939441 1090.759558 1181.803467 1252.515888 1334.593785 1223.685663 1113.365504 1403.362803 1373.674439 965.9804455 1.032105721 1.129173538 1.223423799 1.296626545 1.381595032 1.266780987 1.152575613 1.452785933 1.422052015 1 9.915850174 -6.86327188 1.464561184 1.01195769 1.303813457 0.007795527 0.148825396 0.126670081 0.544576468 0.012498695 0.017578062 1.37E-07 6.86327188 0.291855766 GLGTDEES(ph)ILTLLTSR ddPTM_HeLa_Curcumin_4h_R1 2 GLGTDEESILTLLTSR 16 0 P08758;E9PHT9 P08758 ANXA5 Annexin A5;Annexin 1 0 GLGT(0.001)DEES(0.97)ILT(0.029)LLTSR;GLGT(0.181)DEES(0.714)ILT(0.105)LLTSR ; 196.97 1.50E-07 6242800 1141.36 982.16 848.01 1152.11 988.34 929.45 779.84 821.9 1181.35 1018.95 TRUE FALSE FALSE 1051.020152 1067.053534 879.4379966 1147.342874 976.554691 736.6715929 801.7202116 1072.493526 1051.758861 1054.358437 0.996833823 1.01204059 0.834097747 1.088190538 0.926207499 0.698691799 0.760386775 1.017200118 0.997534448 1 10.04214969 -5.513917584 24.08519478 0.992130642 0.817843489 0.364407629 0.095892136 181.3118652 487316.3236 0.012786933 0.026722862 3.06E-06 5.513917584 -0.174287152 GLHVVEVTYDDVPIPNS(ph)PFK ddPTM_HeLa_Curcumin_4h_R1 1 GLHVVEVTYDDVPIPNSPFK 20 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 1 0 GLHVVEVTYDDVPIPNS(1)PFK 153.14 4.91E-11 0 1647.8 1762.1 1341.4 1429.9 1544 2466.7 1822.4 1044.1 1434.5 1258.3 TRUE FALSE FALSE 1517.374891 1914.408072 1391.113464 1423.983453 1525.588808 1955.078615 1873.531639 1362.441284 1277.138939 1302.025831 1.165395382 1.470330332 1.068422324 1.09366759 1.171703949 1.501566687 1.438935845 1.046401116 0.980886023 1 10.34654236 -8.80975571 0.27974624 0.896610987 1.306590719 0.277035392 0.161985255 3.421877041 0.477303388 0.492155428 0.133856058 1.55E-09 8.80975571 0.409979732 TGVLLPSSPEAEVPGKLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 TGVLLPSSPEAEVPGKLSPK 20 1 O60285 O60285 NUAK1 NUAK family SNF1-like kinase 1 1 0 TGVLLPS(0.001)S(0.001)PEAEVPGKLS(0.998)PK 85.937 0.00079503 35993000 1553.6 1365.2 1144.9 1442.1 1256 1434.5 781.94 210.89 1472.6 1655.1 TRUE FALSE FALSE 1430.630921 1483.201805 1187.331001 1436.132972 1241.02302 1136.96853 803.8791319 275.1893902 1311.059464 1712.614602 0.835349015 0.866045287 0.693285576 0.838561677 0.724636482 0.663878802 0.469387059 0.160683781 0.765530939 1 10.74198482 -4.592390507 0.548691148 0.919695908 1.77E-41 0.82706594 0.093484272 0.759739954 0.192228565 0.018200229 0.41382685 2.56E-05 4.592390507 -0.919695908 down GLK(ac)EFPIK ddPTM_HeLa_Curcumin_4h_R1 1 GLKEFPIK 8 1 Q9UM07 Q9UM07 PADI4 Protein-arginine deiminase type-4 0 1 GLK(1)EFPIK 79.713 0.018931 0 404.74 226.51 604.36 400.28 528.46 450.26 269.42 143.97 393.95 523.43 FALSE TRUE FALSE 372.7044019 246.0885151 626.7581132 398.6237474 522.1584596 356.8710005 276.9792001 187.8657902 350.7346706 541.6191535 0.688130025 0.454357113 1.157193406 0.735985323 0.964069413 0.658896566 0.511391073 0.346859577 0.647566963 1 9.081134948 -4.781035057 1.99578696 0.83977682 0.367803497 0.375489705 0.192367859 0.267850732 1.967811898 0.028075707 0.158136025 1.66E-05 4.781035057 -0.471973323 GLKEGMNPS(ph)YDEYADSDEDQHDAYLER ddPTM_HeLa_Curcumin_4h_R1 1 GLKEGMNPSYDEYADSDEDQHDAYLER 27 1 Q08945 Q08945 SSRP1 FACT complex subunit SSRP1 1 0 GLKEGMNPS(0.519)Y(0.436)DEY(0.028)ADS(0.017)DEDQHDAYLER 86.18 6.60E-05 9467500 1431.9 902.3 878.96 892.06 599.92 1297.5 735.69 941.69 1669.3 1132.6 TRUE FALSE FALSE 1318.563604 980.2907914 911.5350308 888.3688921 592.7663458 1028.383874 756.3314814 1228.806946 1486.181966 1171.957766 1.125094814 0.836455733 0.777788294 0.758021251 0.505791559 0.877492265 0.645357285 1.048507875 1.268119048 1 10.19470486 -7.108753099 3.903160075 1.058712685 0.758296889 0.520687774 0.150989874 0.137032297 3.707816101 0.021961351 0.027279583 7.78E-08 7.108753099 -0.300415796 GLKEGMNPSYDEYADS(ph)DEDQHDAYLER ddPTM_HeLa_Curcumin_4h_R1 5 GLKEGMNPSYDEYADSDEDQHDAYLER 27 1 Q08945 Q08945 SSRP1 FACT complex subunit SSRP1 1 0 GLKEGMNPSYDEY(0.003)ADS(0.997)DEDQHDAYLER;GLKEGMNPSYDEY(0.001)ADS(0.996)DEDQHDAY(0.002)LER;GLKEGMNPSY(0.001)DEY(0.015)ADS(0.984)DEDQHDAYLER;GLKEGMNPS(0.002)Y(0.004)DEY(0.133)ADS(0.861)DEDQHDAYLER;GLKEGMNPSYDEY(0.002)ADS(0.998)DEDQHDAYLER ;;;; 143.84 1.24E-08 217011000 13120.3 8759.6 9228.2 10737.8 8117.86 16589.7 9126.6 10289.4 14595.5 12523.4 TRUE FALSE FALSE 12081.81441 9516.740792 9570.20521 10693.36983 8021.059821 13148.80922 9382.667833 13426.59069 12994.41017 12958.58722 0.932340402 0.734396476 0.738522267 0.825195652 0.618976412 1.014679223 0.724050213 1.036115316 1.002764418 1 13.66162082 -7.44166793 4.424201673 0.971360913 0.807816991 0.278922145 0.122586648 0.206159118 7.038328212 0.019854118 0.022304627 3.62E-08 7.44166793 -0.163543923 GLKPSCTIIPLMK(ac)K ddPTM_HeLa_Curcumin_4h_R1 5 GLKPSCTIIPLMKK 14 2 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 1 ;;;; GLKPSCTIIPLMK(1)K;GLKPSCTIIPLMK(1)K;GLKPSCTIIPLMK(1)K;GLKPSCTIIPLMK(1)K;GLKPSCTIIPLMK(1)K 155.39 0.00017811 12242580 16186.66 11999.59 14192.79 14419.73 13239.9 16582.3 11430.32 11797.53 15161.04 14468.09 FALSE TRUE FALSE 14905.46878 13036.78109 14718.78728 14360.06498 13082.02284 13142.94406 11751.02402 15394.54259 13497.91184 14970.85505 0.995632429 0.870810722 0.983162767 0.95920139 0.87383271 0.877902031 0.784926711 1.028300824 0.90161262 1 13.869869 -6.744099156 0.649327398 1.001903379 0.885731143 0.000300349 0.073278488 0.589700773 0.511764955 0.015585687 0.027257693 1.80E-07 6.744099156 -0.116172236 S(ph)QCRNSPSNLSSSSDTGSVGGTYR ddPTM_HeLa_Curcumin_4h_R1 1 SQCRNSPSNLSSSSDTGSVGGTYR 24 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 S(0.685)QCRNS(0.31)PS(0.005)NLSSSSDTGSVGGTYR 86.761 5.44E-05 13698000 290.49 384.3 158.6 332.14 313.34 293.81 126.09 0 368.69 271.43 TRUE FALSE FALSE 267.49741 417.5171796 164.4778555 330.7656927 309.6036251 232.8704941 129.627746 0 328.2456294 280.8621723 0.952415228 1.486555403 0.585617686 1.177679749 1.102332944 0.829127298 0.461535083 0 1.168707152 1 8.133718519 -4.591600668 1.907558422 1.008281669 6.85E-15 0.70562011 0.220230594 0.174839483 1.02210783 0.028056041 0.246318208 2.56E-05 4.591600668 -1.008281669 down GLLAQGLRPESPPPAGPLLNGAPAGES(ph)PQPK ddPTM_HeLa_Curcumin_4h_R1 2 GLLAQGLRPESPPPAGPLLNGAPAGESPQPK 31 1 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 0 GLLAQGLRPES(0.286)PPPAGPLLNGAPAGES(0.714)PQPK;GLLAQGLRPES(0.004)PPPAGPLLNGAPAGES(0.996)PQPK ; 101.76 2.65E-09 2691700000 4100.5 3459 3594.2 4037 3843.1 4420.3 2722.8 3134.9 4323.3 3837.9 TRUE FALSE FALSE 3775.941098 3757.980547 3727.404214 4020.295964 3797.273543 3503.479953 2799.19444 4090.716579 3849.044806 3971.266739 0.95081528 0.946292655 0.938593265 1.012345991 0.956186978 0.88220716 0.704861855 1.030078523 0.969223439 1 11.95538355 -5.234302389 4.062518588 0.972897059 0.85253047 0.239356036 0.0764531 0.17846555 6.777446797 0.009806762 0.025463742 5.83E-06 5.234302389 -0.120366589 GLLASDLNTDGDMRVT(ph)PEPGAGPTQGLLR ddPTM_HeLa_Curcumin_4h_R1 2 GLLASDLNTDGDMRVTPEPGAGPTQGLLR 29 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9;V9GYX5;C9JVY3;V9GY85;H7C3H1 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 0 GLLAS(0.005)DLNT(0.011)DGDMRVT(0.984)PEPGAGPTQGLLR;GLLAS(0.025)DLNT(0.022)DGDMRVT(0.938)PEPGAGPT(0.014)QGLLR ; 67.335 0.00015762 99236000 3994.56 3331.9 3103.96 3301.79 2727.55 2721.31 2328.52 2125.93 4257.64 3391.21 TRUE FALSE FALSE 3678.386361 3619.894589 3218.995488 3288.128068 2695.025748 2156.879631 2393.852004 2774.11627 3790.587544 3509.054295 1.048255755 1.031586942 0.917339892 0.937041092 0.768020532 0.61466123 0.682192922 0.790559518 1.080230519 1 11.77686656 -5.869270359 1.555267679 1.020100281 0.689716368 0.872105812 0.05540406 0.088217089 0.429654856 0.008372792 0.018934633 1.35E-06 5.869270359 -0.330383913 GLLDDLRNDLDR ddPTM_HeLa_Curcumin_4h_R1 2 GLLDDLRNDLDR 12 1 Q07065 Q07065 CKAP4 Cytoskeleton-associated protein 4 0 0 ; ; 133.42 0.0017514 4994200 2414.18 2217.27 2208.37 2724.9 2190.1 2741.8 1176.6 796.06 3175.8 2338.9 FALSE FALSE TRUE 2223.095106 2408.920939 2290.214135 2713.625086 2163.984488 2173.119774 1209.612229 1038.775029 2827.422685 2420.176601 0.918567308 0.995349239 0.94630042 1.121250856 0.894143215 0.897917851 0.499803291 0.429214558 1.168271226 1 11.24089661 -4.766782857 2.876994749 0.969453431 0.429625648 0.859518561 0.085688439 0.048338121 0.792167039 0.008474977 0.036999962 1.71E-05 4.766782857 -0.539827782 down GLLDVTCK ddPTM_HeLa_Curcumin_4h_R1 2 GLLDVTCK 8 0 E5RJR5;P63208;E7ERH2;F8W8N3;P63208-2 E5RJR5 SKP1 S-phase kinase-associated protein 1 0 0 ; ; 129.47 0.0017143 8215800 10161.4 8370.3 8812.9 7845.4 9067.7 12167.9 8772.8 8655.8 9473 8715.4 FALSE FALSE TRUE 9357.114468 9093.791435 9139.513827 7812.937814 8959.5736 9644.14038 9018.941157 11294.91357 8433.8356 9018.259501 1.03757432 1.008375445 1.013445424 0.866346529 0.993492547 1.069401516 1.000075586 1.252449386 0.935195489 1 13.13863331 -4.260302157 24.80937592 1.008013504 1.252449472 0.659413535 0.055119913 39.61896258 864191.6313 0.00707658 0.058445419 5.49E-05 4.260302157 0.244435968 GLLEFEHQR ddPTM_HeLa_Curcumin_4h_R1 2 GLLEFEHQR 9 0 F5H6X6;Q14697;Q14697-2;E9PKU7;E9PNH1 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 0 ; ; 179.37 0.0011507 15144900 24292.7 16160.9 23864.9 21684.9 22662.4 24509.5 17035.4 10324.4 21497.1 20999.9 FALSE FALSE TRUE 22369.90716 17557.77618 24749.35419 21595.17363 22392.16568 19425.95342 17513.36748 13472.26203 19138.92191 21729.64496 1.029464918 0.808010265 1.13896726 0.993811619 1.030489257 0.893983931 0.805966573 0.619994577 0.880774718 1 14.40737698 -4.470570995 1.26446025 1.007891776 0.534022245 0.616760994 0.087930721 0.374666014 0.657181772 0.010783893 0.207357558 3.38E-05 4.470570995 -0.473869531 GLLLYGPPGTGK ddPTM_HeLa_Curcumin_4h_R1 2 GLLLYGPPGTGK 12 0 K7EM02;K7EIJ8;Q8IYT4-2;Q8IYT4 K7EM02 KATNAL2 Katanin p60 ATPase-containing subunit A-like 2 0 0 ; ; 188.04 3.18E-10 10692300 6906.6 5783.2 5976.2 5775.4 5170.7 7493.4 5453.5 5630.8 6407.1 5621.1 FALSE FALSE TRUE 6359.935322 6283.074039 6197.683229 5751.502925 5109.04278 5939.184372 5606.510533 7347.604999 5704.25716 5816.432807 1.093442585 1.080228079 1.065547121 0.988836821 0.878380779 1.021104269 0.96390876 1.263249356 0.980714013 1 12.50591891 -6.26835293 24.05229472 1.049989094 1.011657432 0.002714412 0.097104955 1030.009467 3583412.298 0.014476478 0.022460212 5.39E-07 6.26835293 -0.038331662 QQTST(ph)PVLTQPGR ddPTM_HeLa_Curcumin_4h_R1 1 QQTSTPVLTQPGR 13 0 Q5T5U3;A0A087WW76;A0A452Q6Z5;E7ESW5;A0A1B0GV73;Q5T5U3-3 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 0 QQT(0.001)S(0.091)T(0.903)PVLT(0.005)QPGR 100.18 0.020141 11095000 2499 2155.6 2262.2 2980.6 2527.8 2796.4 1377.1 549.3 3145.2 2374.5 TRUE FALSE FALSE 2301.201513 2341.920459 2346.039122 2968.267067 2497.657636 2216.395118 1415.73772 716.7790413 2800.179429 2457.013698 0.936584731 0.953157266 0.954833554 1.208079169 1.016542007 0.902068686 0.576202616 0.291727735 1.139667813 1 11.26269019 -4.588233934 2.019247508 0.988108215 0.271311017 0.88005383 0.088833149 0.093284717 0.626962749 0.011571556 0.096103131 2.58E-05 4.588233934 -0.716797198 down GLLPGLLPAPADKLT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 GLLPGLLPAPADKLTPK 17 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 0 GLLPGLLPAPADKLT(1)PK;GLLPGLLPAPADKLT(1)PK ; 153.06 0.00015758 72679000 8131.8 7121.5 6904.3 8081.4 6122.6 11531 9771.6 5468.2 7703.2 5450.2 TRUE FALSE FALSE 7488.159449 7737.050727 7160.179432 8047.961308 6049.591994 9139.340619 10045.7648 7135.429008 6858.178232 5639.594044 1.327783417 1.371916253 1.269626745 1.42704621 1.072699905 1.620567109 1.781292185 1.265238056 1.216076579 1 12.4613756 -12.00129942 0.106036731 2.82E-12 1.718003143 0.283525306 0.188307957 49.50084725 0.555632519 12.4362501 1.452274653 9.97E-13 12.00129942 1.718003143 SSEMS(ph)PVPMR ddPTM_HeLa_Curcumin_4h_R1 2 SSEMSPVPMR 10 0 E9PCH4;Q8TEU7;Q8TEU7-4;A0A5F9ZHG7;B7Z7Y1;Q8TEU7-2;Q8TEU7-5;Q8TEU7-3;D6RE77 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 0 S(0.013)SEMS(0.987)PVPMR;S(0.111)S(0.001)EMS(0.887)PVPMR ; 107.06 0.0088744 102243000 8436.4 7121.3 7305 7265.7 7383 7381.2 3764.1 1253.76 8026.4 6128.1 TRUE FALSE FALSE 7768.650038 7736.83344 7575.729726 7235.636459 7294.962547 5850.255917 3869.710515 1636.025652 7145.924001 6341.051019 1.225136025 1.220118466 1.194711997 1.141078417 1.150434293 0.922600354 0.610263268 0.258005439 1.126930532 1 12.63050627 -4.582367583 1.485237531 1.130702744 0.162960391 0.952386086 0.065529656 0.143965513 0.436830534 0.014323937 0.171153667 2.62E-05 4.582367583 -0.967742353 down DSLITPHVS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 DSLITPHVSR 10 0 P49792;J3KNE0;J3KQ37;A6NKT7;Q99666;O14715;F8VYC4;P0DJD0;P0DJD1;A0A1W2PNU4;A0A286YES2;Q7Z3J3;H7BZ48 P49792 RANBP2;RGPD3;RGPD8;RGPD5;RGPD1;RGPD2;RGPD4;RGPD6 E3 SUMO-protein ligase RanBP2;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4 1 0 DSLIT(0.006)PHVS(0.994)R 81.278 0.014284 10662000 11580 10877 10368 9173.5 11637 11215 6815.3 3516.3 10950 10253 TRUE FALSE FALSE 10663.43078 11817.15941 10752.2472 9135.542488 11498.23638 8888.882581 7006.518976 4588.403683 9748.812396 10609.29099 1.005103055 1.113850061 1.013474625 0.861088879 1.08378933 0.837839455 0.660413498 0.432489192 0.918893865 1 13.37304062 -4.581429719 1.352137426 1.007735298 0.352241927 0.869000099 0.071897793 0.161068838 0.381230985 0.009230826 0.122464399 2.62E-05 4.581429719 -0.65549337 down ADGGTGDSSPSPGSSLPS(ph)PLSDPR ddPTM_HeLa_Curcumin_4h_R1 2 ADGGTGDSSPSPGSSLPSPLSDPR 24 0 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 0 ADGGTGDSSPSPGS(0.002)S(0.002)LPS(0.983)PLS(0.014)DPR;ADGGTGDSSPSPGS(0.003)S(0.096)LPS(0.854)PLS(0.046)DPR ; 214.86 9.01E-24 17093000 2182.92 2122.59 2238.1 2384.14 2386.61 2806.2 2204.2 5014.3 2811.21 2004.54 TRUE FALSE FALSE 2010.139579 2306.057222 2321.045955 2374.27506 2358.151234 2224.162488 2266.04392 6543.136987 2502.827296 2074.197616 0.969116714 1.111782794 1.119009075 1.144671579 1.136898055 1.072300185 1.092491816 3.154538862 1.20664843 1 11.01833764 -4.261063365 5.790885365 1.032090839 3.219923494 0.980665607 0.086403939 0.012304146 1.796862551 0.012011045 0.105618666 5.48E-05 4.261063365 2.187832655 up GLLSGQTS(ph)PTNAK ddPTM_HeLa_Curcumin_4h_R1 1 GLLSGQTSPTNAK 13 0 G3V1P3;Q969J3 G3V1P3 LOH12CR1 Loss of heterozygosity 12 chromosomal region 1 protein 1 0 GLLSGQT(0.175)S(0.592)PT(0.233)NAK 137.09 0.0011777 32786000 2133 2257.6 1672 1517.4 1947.1 2692.6 2269.6 2381.2 1828.1 1558.7 TRUE FALSE FALSE 1964.170799 2452.736884 1733.965791 1511.121401 1923.882104 2134.124408 2333.278868 3107.216918 1627.562004 1612.864709 1.217814977 1.520733184 1.075084464 0.936917643 1.19283539 1.323188731 1.446667445 1.926520495 1.00911254 1 10.65540971 -3.953096121 0.976309135 1.126299646 2.805347045 0.706178177 0.155810042 1.418787274 0.694068206 0.025910277 2.881672982 0.000111405 3.953096121 1.679047399 GLLSQGS(ph)PLSWEETKR ddPTM_HeLa_Curcumin_4h_R1 2 GLLSQGSPLSWEETKR 16 1 A0A0C4DGB2;E1CEI4;P48506;D6RGF8 A0A0C4DGB2 GCLC Glutamate--cysteine ligase catalytic subunit 1 0 GLLS(0.015)QGS(0.812)PLS(0.169)WEET(0.003)KR;GLLS(0.289)QGS(0.709)PLS(0.002)WEETKR ; 89.913 0.0028117 24306000 2238.3 1699.56 2108.8 2129.62 2317.6 2432.02 1759.28 1612.82 2439.3 2041.9 TRUE FALSE FALSE 2061.136193 1846.462393 2186.953983 2120.808197 2289.964134 1927.591637 1808.640662 2104.561393 2171.714893 2112.855873 0.975521435 0.873917818 1.035070121 1.00376378 1.083824109 0.912315725 0.856017055 0.99607428 1.027857565 1 11.04497864 GLLT(ph)DSPAATVLAEAR ddPTM_HeLa_Curcumin_4h_R1 1 GLLTDSPAATVLAEAR 16 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 0 GLLT(0.766)DS(0.234)PAATVLAEAR 222.55 2.97E-15 24712000 3757.2 2779.8 3097.2 2999.3 3020 5679.9 5805.7 1926.4 3799.1 2378.7 TRUE FALSE FALSE 3459.813655 3020.073525 3211.984957 2986.889691 2983.988472 4501.824714 5968.592317 2513.750492 3382.348235 2461.359648 1.405651408 1.226994002 1.304963685 1.21351209 1.212333384 1.828999154 2.424916782 1.021285327 1.374178795 1 11.26523976 -1 0.093305587 0.723449894 3.629146866 0.12066711 0.380625107 140.3010524 0.943850582 3.767671694 52.40338028 0.1 1 2.905696973 GLLTDS(ph)PAATVLAEAR ddPTM_HeLa_Curcumin_4h_R1 1 GLLTDSPAATVLAEAR 16 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 0 GLLT(0.017)DS(0.929)PAAT(0.054)VLAEAR 94.339 0.0043784 10329000 2521.3 2345.8 2180.4 2135.9 2525.7 3768.1 3657.2 1667.8 3080 2384.2 TRUE FALSE FALSE 2321.736445 2548.560499 2261.207542 2127.062212 2495.582677 2986.553585 3759.811189 2176.304542 2742.131706 2467.050773 0.941097958 1.033039339 0.916563034 0.86218826 1.011565187 1.210576458 1.524010463 0.882148258 1.111501934 1 11.26857169 -5.283415893 4.291456344 0.964616605 1.240532442 0.287491111 0.158283338 0.142761036 6.424748821 0.019344191 0.047318531 5.21E-06 5.283415893 0.275915837 GLLYDS(ph)DEEDEERPAR ddPTM_HeLa_Curcumin_4h_R1 14 GLLYDSDEEDEERPAR 16 1 P49736 P49736 MCM2 DNA replication licensing factor MCM2 1 0 GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR;GLLYDS(1)DEEDEERPAR ;;;;;;;;;;;;; 255.39 2.98E-39 12308573700 36439.72 31657.47 33182.27 33929.82 33829.32 40298.06 31066.77 28941.67 37624.04 33361.42 TRUE FALSE FALSE 33555.47771 34393.80064 34412.03412 33789.4274 33425.92745 31939.7881 31938.41995 37765.85195 33496.77694 34520.72686 0.972038562 0.996323188 0.996851377 0.978815641 0.968285737 0.925235098 0.925195465 1.094005121 0.970338112 1 15.07517522 -6.002790608 5.245650818 0.988029386 0.970828472 0 0.044944123 0.582582544 50.35288381 0.006361346 0.011246458 9.94E-07 6.002790608 -0.017200913 GLLYDS(ph)DEEDEERPARK ddPTM_HeLa_Curcumin_4h_R1 4 GLLYDSDEEDEERPARK 17 2 P49736 P49736 MCM2 DNA replication licensing factor MCM2 1 0 GLLYDS(1)DEEDEERPARK;GLLYDS(1)DEEDEERPARK;GLLYDS(1)DEEDEERPARK;GLLYDS(1)DEEDEERPARK ;;; 99.663 0.0016213 632865000 15867.1 12313.8 13587.5 13547.2 12724.8 16446.8 13009.7 13356.7 16316.5 14007.1 TRUE FALSE FALSE 14611.20229 13378.15 14091.0647 13491.14528 12573.06507 13035.54829 13374.71717 17429.09634 14526.62077 14493.84568 1.008096996 0.923022798 0.972210206 0.930818885 0.867476124 0.899385061 0.922785951 1.202517036 1.002261311 1 13.82315282 -7.280761893 23.01875834 1.003823588 0.95182017 0.045298269 0.086762137 600.6145493 715505.2603 0.014252167 0.016316201 5.24E-08 7.280761893 -0.052003418 GLMAGGRPEGQYS(ph)EDEDTDTDEYK ddPTM_HeLa_Curcumin_4h_R1 1 GLMAGGRPEGQYSEDEDTDTDEYK 24 1 H0YE35;H0YC88;Q9NPQ8-2;Q9NPQ8-4;Q9NPQ8;Q9NPQ8-3 H0YE35 RIC8A Synembryn-A 1 0 GLMAGGRPEGQY(0.164)S(0.826)EDEDT(0.007)DT(0.003)DEYK 72.927 0.00033687 7030600 639.76 572.31 659.04 647.24 567.81 642.99 467.82 448.83 683.37 612.82 TRUE FALSE FALSE 589.1223209 621.7779262 683.4646022 644.5618924 561.0392366 509.626626 480.9457701 585.6762008 608.4060207 634.1154494 0.929045841 0.980543727 1.077823609 1.01647404 0.88475882 0.803681138 0.758451431 0.92361131 0.959456234 1 9.308601716 -5.565328351 4.246262644 0.979057426 0.823729782 0.65513141 0.05414582 0.108117895 4.249643259 0.008533071 0.018017938 2.72E-06 5.565328351 -0.155327644 GLMDHT(ph)ESGKICQRWDHQTPHRHK ddPTM_HeLa_Curcumin_4h_R1 1 GLMDHTESGKICQRWDHQTPHRHK 24 3 P14210-5;P14210-2;P14210-4;P14210-3;P14210 P14210-5 HGF Hepatocyte growth factor;Hepatocyte growth factor alpha chain;Hepatocyte growth factor beta chain 1 0 GLMDHT(0.804)ES(0.196)GKICQRWDHQTPHRHK 42.123 0.015156 42295000 299.57 282.2 316.16 255.66 401.8 296.25 252.57 282.46 272.62 237.43 TRUE FALSE FALSE 275.8587184 306.5921105 327.8771677 254.6021467 397.0087974 234.8044106 259.6564344 368.5807537 242.7142681 245.6806748 1.122834422 1.247929292 1.334566375 1.036313283 1.615954522 0.955730078 1.056885873 1.500243167 0.987925763 1 7.94064057 -7.821548646 0.949885116 1.02586002 1.24123101 0.205730502 0.195141474 0.576277707 1.104398776 0.04911481 0.042785376 1.51E-08 7.821548646 0.21537099 GLNGCES(ph)PDADDYFEHS(ph)PLSEDR ddPTM_HeLa_Curcumin_4h_R1 2 GLNGCESPDADDYFEHSPLSEDR 23 0 Q02078-8;Q02078-7;Q02078-4;Q02078-6;Q02078-2 Q02078-8 MEF2A Myocyte-specific enhancer factor 2A 2 0 GLNGCES(0.921)PDADDY(0.077)FEHS(0.982)PLS(0.02)EDR;GLNGCES(1)PDADDY(0.001)FEHS(0.834)PLS(0.166)EDR ; 99.515 0.00015047 7503400 2788.1 2685.5 2184.07 2871.6 2852.7 2727.9 2164.54 2706 2693.3 2549.5 TRUE FALSE FALSE 2567.418943 2917.622654 2265.013556 2859.71808 2818.683416 2162.10279 2225.271167 3531.046943 2397.851728 2638.094935 0.973209458 1.105958173 0.858579244 1.084008783 1.068454125 0.819569744 0.843514438 1.338483652 0.90893307 1 11.36528077 -4.247225546 24.47452853 0.979909899 1.338483983 0.556856113 0.099541386 1048.824461 1805910.708 0.012756163 0.354337195 5.66E-05 4.247225546 0.358574084 GLNGCES(ph)PDADDYFEHSPLSEDR ddPTM_HeLa_Curcumin_4h_R1 1 GLNGCESPDADDYFEHSPLSEDR 23 0 Q02078-8;Q02078-7;Q02078-4;Q02078-6;Q02078-2 Q02078-8 MEF2A Myocyte-specific enhancer factor 2A 1 0 GLNGCES(0.989)PDADDY(0.011)FEHSPLSEDR 117.66 2.19E-06 11053000 1087.4 1121.1 1012.9 1002.5 1158.7 1314.2 1193.2 695.94 797.12 874.76 TRUE FALSE FALSE 1001.331143 1218.002888 1050.438965 998.3519206 1144.883259 1041.620106 1226.677981 908.1289023 709.6779303 905.1578449 1.106250306 1.345624849 1.16050363 1.102958922 1.264843768 1.150760734 1.355208915 1.003282364 0.784037761 1 9.822025587 -7.863252829 1.457206604 1.029363808 1.198632939 0.380106133 0.129522821 0.275966995 1.220492984 0.021645154 0.01981938 1.37E-08 7.863252829 0.169269131 GLNGCESPDADDY(ph)FEHSPLSEDR ddPTM_HeLa_Curcumin_4h_R1 1 GLNGCESPDADDYFEHSPLSEDR 23 0 Q02078-8;Q02078-7;Q02078-4;Q02078-6;Q02078-2 Q02078-8 MEF2A Myocyte-specific enhancer factor 2A 1 0 GLNGCESPDADDY(0.602)FEHS(0.37)PLS(0.028)EDR 124.76 2.56E-05 10129000 989.75 856.69 1078.8 1206.1 1159.8 2050.5 1139.5 694.19 1034.3 1201.4 TRUE FALSE FALSE 911.4102431 930.7384663 1118.781277 1201.109478 1145.970142 1625.203186 1171.471303 905.8453353 920.8398777 1243.148561 0.733146683 0.748694481 0.899957827 0.96618338 0.921828797 1.307328213 0.942342163 0.72867022 0.740731966 1 10.279783 -6.244629458 2.712650219 0.860104098 0.991613079 0.170217093 0.15459087 0.489865309 7.164549688 0.026537543 0.044898053 5.69E-07 6.244629458 0.131508981 GLNGGITPLNSIS(ph)PLKK ddPTM_HeLa_Curcumin_4h_R1 1 GLNGGITPLNSISPLKK 17 1 E5RJM0;B7ZLQ8;Q17RY0-2;Q17RY0;H0YBG1 E5RJM0 CPEB4 Cytoplasmic polyadenylation element-binding protein 4 1 0 GLNGGITPLNS(0.131)IS(0.869)PLKK 55.621 0.020074 17975000 1732.6 1155.5 1178.2 1127.9 1226.1 1661.2 938.31 546.48 1494.8 1063.4 TRUE FALSE FALSE 1595.462882 1255.376271 1221.865128 1123.233049 1211.479558 1316.648394 964.6364533 713.0992363 1330.82418 1100.353071 1.449955404 1.140884962 1.110430062 1.020793306 1.100991664 1.196569019 0.876660845 0.648064022 1.209451961 1 10.1037508 -3.915400762 0.842638592 1.193443128 7.28E-13 0.619360414 0.12490876 2.530383381 0.88845905 0.028618766 3.210345228 0.000121506 3.915400762 -1.193443128 TLTEPSVDFNHS(ph)DDFTPISTVQK ddPTM_HeLa_Curcumin_4h_R1 2 TLTEPSVDFNHSDDFTPISTVQK 23 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 0 T(0.003)LT(0.013)EPS(0.273)VDFNHS(0.71)DDFT(0.001)PISTVQK;TLTEPS(0.028)VDFNHS(0.971)DDFT(0.001)PISTVQK ; 113.17 3.88E-06 111032000 6301.8 4985 6301.8 5539.2 5994.5 6767.7 2693.2 578.36 6627.5 5779.4 TRUE FALSE FALSE 5803.00588 5415.881187 6535.350252 5516.280258 5923.019503 5364.002732 2768.763944 754.6993016 5900.479831 5980.23372 0.970364396 0.905630355 1.092825224 0.922418841 0.990432779 0.896955367 0.462985909 0.126198964 0.986663751 1 12.54598615 -4.579748286 1.916007646 0.984475386 0.080928568 0.970300698 0.049242077 0.046389731 0.271262614 0.006569772 0.059149149 2.63E-05 4.579748286 -0.903546818 down SEPSGEINIDS(ph)SGETVGSGER ddPTM_HeLa_Curcumin_4h_R1 2 SEPSGEINIDSSGETVGSGER 21 0 P42695;E9PKK4;G3V1A9 P42695 NCAPD3 Condensin-2 complex subunit D3 1 0 SEPSGEINIDS(0.676)S(0.324)GETVGSGER;SEPS(0.01)GEINIDS(0.489)S(0.489)GET(0.012)VGSGER ; 162.37 4.28E-07 14393000 2808.1 2346.5 2486.7 2979.1 3009.3 3053.2 1968.33 1071.91 3398.6 3096.9 TRUE FALSE FALSE 2585.835922 2549.321004 2578.85929 2966.773274 2973.416063 2419.931903 2023.556042 1398.730425 3025.782083 3204.517044 0.806934676 0.795539849 0.804757551 0.925809797 0.927882742 0.75516275 0.631469895 0.436487123 0.944224057 1 11.64589123 -4.575775053 1.386372247 0.893112643 0.379855524 0.824009329 0.067062675 0.285765666 0.718245344 0.013220191 0.173302393 2.66E-05 4.575775053 -0.513257119 down GLNPDGT(ph)PALST(ph)LGGFSPASKPS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 GLNPDGTPALSTLGGFSPASKPSSPR 26 1 Q9UK58-6;Q9UK58 Q9UK58-6 CCNL1 Cyclin-L1 3 0 GLNPDGT(0.679)PALS(0.468)T(0.751)LGGFS(0.141)PAS(0.301)KPS(0.495)S(0.165)PR 51.19 0.0080272 0 2018.6 1785.4 1850.8 1944.8 1584.7 1379.2 841.23 1016.8 1669.3 2052.1 TRUE FALSE FALSE 1858.82568 1939.72202 1919.392276 1936.752933 1565.803488 1093.138373 864.8326497 1326.817639 1486.181966 2123.410322 0.875396366 0.913493732 0.903919632 0.912095469 0.737400337 0.514803174 0.407284754 0.624852213 0.699903335 1 11.05216747 -5.496396077 2.188845521 0.934031786 0.49952261 0.742243199 0.094331731 0.069526257 0.657088997 0.0098855 0.024997086 3.19E-06 5.496396077 -0.434509176 GLNPDGTPALSTLGGFS(ph)PAS(ph)KPSSPR ddPTM_HeLa_Curcumin_4h_R1 1 GLNPDGTPALSTLGGFSPASKPSSPR 26 1 Q9UK58-6;Q9UK58 Q9UK58-6 CCNL1 Cyclin-L1 2 0 GLNPDGT(0.008)PALS(0.071)T(0.015)LGGFS(0.843)PAS(0.528)KPS(0.204)S(0.331)PR 89.392 1.74E-05 220020000 2349.1 1605.3 1562.9 1764.7 1640.6 2015.7 1288.9 1081.4 1955.7 1652.7 TRUE FALSE FALSE 2163.166256 1744.054979 1620.822449 1757.398139 1621.036917 1597.621098 1325.063065 1411.113882 1741.164603 1710.131202 1.264912455 1.019836944 0.947776666 1.027639363 0.947902076 0.934209666 0.774831231 0.825149486 1.018146795 1 10.7398913 -5.604675397 0.722011763 1.11697463 0.78772246 0.529304085 0.085955993 0.540406444 0.469172491 0.021328065 0.101299163 2.48E-06 5.604675397 -0.32925217 GLNPDGTPALSTLGGFS(ph)PASKPSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 GLNPDGTPALSTLGGFSPASKPSSPR 26 1 Q9UK58-6;Q9UK58 Q9UK58-6 CCNL1 Cyclin-L1 2 0 GLNPDGT(0.001)PALS(0.229)T(0.014)LGGFS(0.756)PAS(0.036)KPS(0.279)S(0.686)PR 100.07 2.31E-06 181330000 2253.1 2009.8 1877.3 2393.4 2155.8 2708.4 1493.3 1036.8 2075.9 1930.7 TRUE FALSE FALSE 2074.764758 2183.518157 1946.874389 2383.496745 2130.093493 2146.64731 1535.197979 1352.915547 1848.178964 1997.791681 1.03852908 1.092965887 0.974513213 1.193065707 1.066224028 1.074510085 0.768447478 0.677205516 0.925110952 1 10.96419044 -4.677700407 4.394348752 1.039796575 0.699809105 0.775593864 0.069914559 0.061960408 2.146832519 0.008662158 0.03523989 2.10E-05 4.677700407 -0.33998747 SDS(ph)VSASER ddPTM_HeLa_Curcumin_4h_R1 2 SDSVSASER 9 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 S(0.078)DS(0.921)VS(0.002)ASER;S(0.06)DS(0.924)VS(0.015)ASER ; 163.84 0.00041497 358990000 4304.2 4016.8 4742 4729.3 3451.4 4743.7 5181 11990.9 3992.9 4332.5 TRUE FALSE FALSE 3963.518028 4363.994293 4917.742691 4709.73141 3410.244309 3759.803147 5326.364916 15646.87021 3554.88886 4483.054053 0.88411114 0.973442266 1.096962614 1.050563155 0.760696674 0.838670046 1.188110795 3.490225642 0.792961409 1 12.13026618 -4.261056359 3.885909896 0.946664213 3.736267784 0.981272938 0.105629381 0.02129344 0.637977398 0.013947446 0.168210427 5.48E-05 4.261056359 2.789603571 up GLNSSFETS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 GLNSSFETSPK 11 0 M0QZ79;M0QXD7;M0R025;M0QYG0;M0QYA8;Q8IV63-2;Q8IV63 M0QZ79 VRK3 Inactive serine/threonine-protein kinase VRK3 1 0 GLNSS(0.001)FET(0.086)S(0.913)PK 113.24 0.0055193 11636000 4129 3395.5 2958.5 3582.2 3685.7 3822.7 2634.8 2799.2 4052.7 3207.8 TRUE FALSE FALSE 3802.185293 3688.99189 3068.144613 3567.377806 3641.750435 3029.828929 2708.725397 3652.663194 3608.128949 3319.270811 1.145488124 1.111386235 0.924342962 1.07474744 1.097153755 0.912799558 0.816060379 1.100441453 1.087024577 1 11.69665062 -5.257486285 24.83738021 1.064464501 0.930396447 0.279060753 0.087485526 291.1557958 1829328.961 0.012948753 0.031660388 5.53E-06 5.257486285 -0.134068054 GLNTS(ph)QES(ph)DDDILDESSSPEGTQK ddPTM_HeLa_Curcumin_4h_R1 1 GLNTSQESDDDILDESSSPEGTQK 24 0 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 2 0 GLNT(0.21)S(0.809)QES(0.975)DDDILDES(0.003)S(0.001)S(0.001)PEGTQK 85.274 0.00032855 5470400 1197.2 1107.5 1148.5 1209.3 1108.3 1521 958.61 1121.1 1225.2 1206.3 TRUE FALSE FALSE 1102.440357 1203.227365 1191.06442 1204.296237 1095.084246 1205.527455 985.5060166 1462.918229 1090.798625 1248.218835 0.883210801 0.963955463 0.954211222 0.964811781 0.877317515 0.96579816 0.78952984 1.17200461 0.873884126 1 10.28565517 -9.658245238 1.515625237 0.999848888 0.931967085 0 0.101047193 0.872848535 3.619908698 0.058781144 0.013356001 2.20E-10 9.658245238 -0.067881803 TQSLPVT(ph)EK ddPTM_HeLa_Curcumin_4h_R1 1 TQSLPVTEK 9 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 0 T(0.019)QS(0.031)LPVT(0.95)EK 133.91 0.0095786 32686000 3545.6 2735.3 3445.7 3223.6 2750.9 3394.7 3647.7 7856.6 2617.4 2638.8 TRUE FALSE FALSE 3264.962019 2971.727144 3573.400673 3210.261597 2718.097314 2690.600954 3750.044645 10252.04117 2330.277768 2730.498104 1.195738614 1.088346167 1.308699196 1.175705485 0.995458415 0.985388325 1.373392144 3.754641382 0.853425888 1 11.41494844 -4.261045611 3.772445125 1.103781091 4.029166967 0.976073618 0.1249918 0.023834259 0.645174363 0.015511928 0.193385593 5.48E-05 4.261045611 2.925385876 up GLNYLT(ph)IMAPGNLWHMR ddPTM_HeLa_Curcumin_4h_R1 1 GLNYLTIMAPGNLWHMR 17 0 C9JE25;Q99551 C9JE25 MTERF1 "Transcription termination factor 1, mitochondrial" 1 0 GLNY(0.345)LT(0.655)IMAPGNLWHMR 62.633 0.0071202 0 999.47 623 802.88 901 612.6 755.18 595.62 620.31 777.73 766.43 TRUE FALSE FALSE 920.3608949 676.849344 832.6354391 897.2719007 605.2951451 598.5471554 612.3314942 809.4396634 692.4149648 793.0633855 1.160513664 0.85346185 1.049897719 1.131399983 0.763236781 0.754728016 0.772109147 1.020649394 0.873089059 1 9.631292367 -5.759168391 24.99772698 1.060351757 0.81850049 0.31100649 0.121177572 36.87989734 405942.9427 0.016403792 0.031591633 1.74E-06 5.759168391 -0.241851268 GLPLEGSAK(ac)GK ddPTM_HeLa_Curcumin_4h_R1 2 GLPLEGSAKGK 11 1 Q15291 Q15291 RBBP5 Retinoblastoma-binding protein 5 0 1 ; GLPLEGSAK(1)GK;GLPLEGSAK(1)GK 146.11 1.51E-05 5781700 2250.7 2030.88 2156.38 2250.32 2055.11 2644.9 2336.91 2584.7 2585.3 2068.6 FALSE TRUE FALSE 2072.55472 2206.420218 2236.29734 2241.008772 2030.604155 2096.317926 2402.477405 3372.763132 2301.699058 2140.483696 0.968264661 1.030804496 1.044762613 1.04696372 0.948666023 0.979366453 1.122399301 1.575701388 1.075317258 1 11.06372113 -4.262809641 2.494356742 0.993893456 1.703752119 0.943760094 0.040975932 0.068004494 0.522461653 0.004953267 0.102063886 5.46E-05 4.262809641 0.709858663 GLPLGSAVSS(ph)PVLFS(ph)PVGR ddPTM_HeLa_Curcumin_4h_R1 2 GLPLGSAVSSPVLFSPVGR 19 0 Q8WUM0 Q8WUM0 NUP133 Nuclear pore complex protein Nup133 2 0 GLPLGSAVS(0.129)S(0.871)PVLFS(1)PVGR;GLPLGS(0.011)AVS(0.438)S(0.552)PVLFS(0.999)PVGR ; 145.82 0.00030737 23232800 2963.4 3168.9 3196.5 3220 3189 4386.4 3178.6 2258.64 3679.1 3238.8 TRUE FALSE FALSE 2728.843763 3442.805596 3314.965102 3206.676493 3150.973258 3476.611195 3267.782961 2947.288939 3275.511935 3351.348059 0.814252568 1.027289776 0.989143784 0.956831829 0.940210686 1.03737694 0.975065229 0.879433854 0.977371457 1 11.71052581 -7.229657276 24.99835029 0.912285903 0.973641714 0.063149911 0.062448699 1090.733748 857922.5323 0.013052476 0.01598534 5.89E-08 7.229657276 0.061355811 SVS(ph)PESNDSISEELNHFKPIVCSPCTPPK ddPTM_HeLa_Curcumin_4h_R1 1 SVSPESNDSISEELNHFKPIVCSPCTPPK 29 1 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 0 S(0.185)VS(0.523)PES(0.205)NDS(0.073)IS(0.011)EELNHFKPIVCS(0.002)PCTPPK 47.577 0.0085478 12659000 1106.6 1120.8 1236.5 1196.2 1105 1479.7 747.43 389.88 1493.6 1285.9 TRUE FALSE FALSE 1019.011442 1217.676958 1282.325778 1191.250441 1091.823597 1172.79354 768.4008742 508.7526172 1329.755817 1330.584929 0.765837204 0.915144108 0.963730875 0.895283281 0.820559119 0.881412013 0.57749104 0.382352608 0.999376881 1 10.37784488 -4.574859049 2.107604617 0.891951993 0.362556019 0.85431763 0.072117564 0.135650231 1.002260189 0.012964043 0.106159024 2.66E-05 4.574859049 -0.529395974 down SSS(ph)SPTEATEK ddPTM_HeLa_Curcumin_4h_R1 1 SSSSPTEATEK 11 0 E7EME3;Q9UBG0 E7EME3 MRC2 C-type mannose receptor 2 1 0 S(0.014)S(0.008)S(0.564)S(0.414)PTEATEK 91.961 0.015996 5039400 2620.3 2534.6 2306.8 2634 2278 2620.5 1464.4 1006.3 2972.2 2744.7 TRUE FALSE FALSE 2412.90049 2753.67953 2392.292037 2623.101206 2250.836338 2076.978761 1505.487123 1313.116238 2646.157096 2840.078121 0.849589479 0.969578798 0.842333181 0.923601779 0.792526206 0.731310433 0.530086518 0.462352154 0.931719827 1 11.4717149 -4.573670628 0.683039789 0.932445688 0.240733123 0.921003531 0.048450552 0.493091042 0.203822807 0.010661221 0.241874194 2.67E-05 4.573670628 -0.691712566 down GRLDSSEMDHS(ph)ENEDYTMSSPLPGK ddPTM_HeLa_Curcumin_4h_R1 1 GRLDSSEMDHSENEDYTMSSPLPGK 25 1 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 GRLDS(0.011)S(0.011)EMDHS(0.586)ENEDY(0.167)T(0.192)MS(0.027)S(0.006)PLPGK 45.243 0.011698 18977000 3828.6 3911.7 4347.7 4079.9 4112.1 4948.5 2647.7 1385.1 4810.9 4188.4 TRUE FALSE FALSE 3525.56227 4249.809918 4508.829587 4063.018455 4063.065893 3922.125319 2721.987336 1807.410614 4283.156306 4333.946588 0.81347617 0.980586593 1.040351904 0.93748697 0.937497916 0.90497777 0.62806204 0.417035738 0.988280824 1 12.08146566 -4.571140867 2.219267834 0.9295248 0.406635939 0.890832377 0.061734168 0.114114362 0.954277103 0.011572835 0.090380941 2.68E-05 4.571140867 -0.522888861 down GLPSPYNMSS(ph)APGSR ddPTM_HeLa_Curcumin_4h_R1 2 GLPSPYNMSSAPGSR 15 0 P15924-2;P15924-3;P15924 P15924-2 DSP Desmoplakin 1 0 GLPSPY(0.001)NMS(0.227)S(0.772)APGSR;GLPSPY(0.001)NMS(0.193)S(0.806)APGS(0.001)R ; 86.498 0.012283 72423000 5745.6 4413.1 5564.5 5427.1 5385.7 5567.7 3538.5 2643.6 6510.6 5960.5 TRUE FALSE FALSE 5290.829697 4794.5487 5770.725265 5404.644098 5321.479045 4412.896259 3637.780787 3449.62147 5796.403469 6167.626931 0.857838802 0.777373332 0.935647588 0.876292318 0.862808193 0.715493383 0.589818552 0.559310981 0.939810973 1 12.59049979 -3.620056681 0.361654602 0.946668955 2.87E-23 0.825531139 0.058998584 3.114638784 0.200052282 0.021455305 1.410748463 0.000239852 3.620056681 -0.946668955 GLPSPYNMSSAPGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 GLPSPYNMSSAPGSR 15 0 P15924-2;P15924-3;P15924 P15924-2 DSP Desmoplakin 1 0 GLPSPYNMSSAPGS(1)R 109.07 0.0034474 0 454.62 312.56 594.61 455.93 427.43 524.17 291.08 399.19 577.75 512.51 TRUE FALSE FALSE 418.6363473 339.5762937 616.6467697 454.0434825 422.3331764 415.4512334 299.2469214 520.9011934 514.3722705 530.3196844 0.78940375 0.640323759 1.162783106 0.856169393 0.796374694 0.783397723 0.564276474 0.982239975 0.969928678 1 9.050718489 -9.283054133 0.876202125 1.007104287 0.816317887 0.144556165 0.157131458 0.968154742 1.25695347 0.12461867 0.029263462 5.21E-10 9.283054133 -0.1907864 GLPSTAS(ph)GR ddPTM_HeLa_Curcumin_4h_R1 2 GLPSTASGR 9 0 H7BYT1;P48730-2;P48730 H7BYT1 CSNK1D Casein kinase I isoform delta 1 0 GLPSTAS(1)GR;GLPSTAS(1)GR ; 147.3 0.0018842 84673000 5822.8 6312.9 5288.8 5963.9 6397.3 8030 6538.6 2608.24 7104.5 5645.4 TRUE FALSE FALSE 5361.919236 6858.558946 5484.807581 5939.222962 6321.016376 6364.487483 6722.055518 3403.480369 6325.154125 5841.57723 0.917888958 1.174093687 0.938925801 1.016715645 1.082073578 1.089515251 1.150726123 0.582630381 1.082781906 1 12.51214223 -4.248618067 24.86916153 1.002991257 0.582630094 0.681049336 0.090968513 972.1884973 1885693.867 0.013174974 0.321018212 5.64E-05 4.248618067 -0.420361163 GLPWSCSADEVQR ddPTM_HeLa_Curcumin_4h_R1 2 GLPWSCSADEVQR 13 0 P31943;G8JLB6;E9PCY7;D6RBM0;D6RIH9;D6RAM1;E5RGV0;D6R9T0;D6RFM3;D6RIT2;D6RIU0;D6RDU3;D6RJ04;E7EN40;D6RDL0;D6RF17;D6R9D3;E7EQJ0 P31943;E7EQJ0 HNRNPH1 "Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed" 0 0 ; ; 233.54 7.44E-38 7850400 1382.43 1243.67 1085.93 1426.29 1577.77 1483.72 1198.88 1274.02 1505.87 1314.75 FALSE FALSE TRUE 1273.009207 1351.167293 1126.175521 1420.38839 1558.956123 1175.979747 1232.517346 1662.462833 1340.679829 1360.437465 0.935735188 0.993185889 0.82780396 1.044067388 1.145922664 0.864412939 0.905971335 1.222006065 0.985476998 1 10.40985493 GLQPGEEELPDIS(ph)PPIVIPDDSKDR ddPTM_HeLa_Curcumin_4h_R1 2 GLQPGEEELPDISPPIVIPDDSKDR 25 1 Q92995;Q92995-2 Q92995 USP13 Ubiquitin carboxyl-terminal hydrolase 13 1 0 GLQPGEEELPDIS(1)PPIVIPDDSKDR;GLQPGEEELPDIS(1)PPIVIPDDSKDR ; 102.21 6.29E-07 22107800 2483.5 1737.02 1947.61 1840.35 1935.11 2417.28 1974.21 1985.91 2026.59 2241 TRUE FALSE FALSE 2286.928354 1887.160269 2019.79014 1832.735119 1912.035077 1915.90888 2029.601019 2591.404817 1804.278147 2318.874583 0.986223391 0.813825932 0.871021725 0.79035543 0.824553036 0.826223589 0.875252605 1.11752694 0.778083541 1 11.17920908 -7.309471113 9.654651343 0.993564199 0.867087998 0 0.110241511 0.475912518 93.69641853 0.014480577 0.016558813 4.90E-08 7.309471113 -0.126476202 GLQPS(ph)TPPPKPPR ddPTM_HeLa_Curcumin_4h_R1 1 GLQPSTPPPKPPR 13 1 A0A1B0GTL5 A0A1B0GTL5 1 0 GLQPS(0.998)T(0.002)PPPKPPR 106.29 0.002117 86414000 5838.9 5089.8 5252.5 5047.8 5366 5692 4686.2 3590.9 5892.4 4798 TRUE FALSE FALSE 5376.744904 5529.739632 5447.162271 5026.913541 5302.013955 4511.415038 4817.68216 4685.74888 5246.018462 4964.730143 1.08298835 1.113804673 1.097171873 1.012525031 1.067935981 0.908692901 0.970381475 0.943807366 1.056657323 1 12.27749959 -5.267104679 24.98465227 1.04983855 0.943902669 0.684566098 0.036908098 263.4037987 1161645.104 0.006567493 0.015062658 5.41E-06 5.267104679 -0.105935881 GLQT(ph)PVKDAGGGTGR ddPTM_HeLa_Curcumin_4h_R1 2 GLQTPVKDAGGGTGR 15 1 O15061;H0YL34;A0A075B7B1;O15061-2 O15061 SYNM Synemin 1 0 GLQT(0.995)PVKDAGGGT(0.005)GR;GLQT(1)PVKDAGGGTGR ; 142.57 0.0049469 33068000 4923.6 3606.8 3622.6 3704.4 3804.8 5665.8 4728 3320 4099.8 3697.3 TRUE FALSE FALSE 4533.891865 3918.55572 3756.856743 3689.072174 3759.430245 4490.649213 4860.654955 4332.252717 3650.062197 3825.7809 1.185089262 1.024249904 0.981984291 0.964266452 0.982656964 1.173786302 1.270500084 1.132383905 0.954069847 1 11.90153854 -5.091630161 6.39014748 1.060998988 1.20642418 0.449738069 0.079549155 0.212278737 12.2681334 0.01333241 0.034633025 8.10E-06 5.091630161 0.145425192 GLQTSQDAR ddPTM_HeLa_Curcumin_4h_R1 1 GLQTSQDAR 9 0 P27797 P27797 CALR Calreticulin 0 0 93.429 0.016841 2972900 873.5 1036.5 831.81 832.93 1058.8 1339.2 895.48 721.68 796.82 1031.4 FALSE FALSE TRUE 804.3615533 1126.090441 862.6376103 829.4835564 1046.174502 1061.434824 920.6047587 941.7169098 709.4108395 1067.241073 0.753683093 1.055141589 0.808287492 0.777222295 0.980260719 0.994559571 0.862602445 0.882384433 0.664714709 1 10.05967038 GLQVDLQS(ph)DGAAAEDIVASEQSLGQK ddPTM_HeLa_Curcumin_4h_R1 2 GLQVDLQSDGAAAEDIVASEQSLGQK 26 0 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;A0A3B3IU45 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 0 GLQVDLQS(1)DGAAAEDIVASEQSLGQK;GLQVDLQS(1)DGAAAEDIVASEQSLGQK ; 132.26 2.78E-08 12659300 7094.7 5471.3 6140.1 6374.7 6290 7627.2 4987.8 3774.6 7097.2 6277.4 TRUE FALSE FALSE 6533.147009 5944.214792 6367.657507 6348.32318 6214.995858 6045.232744 5127.744244 4925.458164 6318.654916 6495.539183 1.005789793 0.915122613 0.980312385 0.97733583 0.956809848 0.93067451 0.789425496 0.758283189 0.972768347 1 12.66523357 -4.748312956 1.241495198 0.992458711 0.720084786 0.878010262 0.028677514 0.159353195 0.349214339 0.004491659 0.044248235 1.79E-05 4.748312956 -0.272373925 S(ph)VSPTFLNPSDENLK ddPTM_HeLa_Curcumin_4h_R1 1 SVSPTFLNPSDENLK 15 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 0 S(0.867)VS(0.133)PT(0.001)FLNPSDENLK 287.03 2.66E-77 52246000 6503.2 5374.4 5959.1 5408.2 5138.3 5355.9 3415.7 1785.5 6140.7 5818.1 TRUE FALSE FALSE 5988.464858 5838.939188 6179.949488 5385.822301 5077.029128 4245.025967 3511.535349 2329.890731 5467.080573 6020.278542 0.994715579 0.969878577 1.026522186 0.894613474 0.8433213 0.705121189 0.583284532 0.387007132 0.908110901 1 12.55561452 -4.56971112 0.678508559 1.001255133 0.154075364 0.964243283 0.037693979 0.149902043 0.060810387 0.003914812 0.089676999 2.69E-05 4.56971112 -0.847179769 down GLS(ph)ASLPDLDSENWIEVK ddPTM_HeLa_Curcumin_4h_R1 1 GLSASLPDLDSENWIEVK 18 0 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50;H0YBW1;H0YC73 Q6PKG0 LARP1 La-related protein 1 1 0 GLS(0.5)AS(0.5)LPDLDSENWIEVK 75.611 0.0044483 5428900 65.129 49.944 182.75 108.41 0 0 107.49 138.06 60.648 155.62 TRUE FALSE FALSE 59.97397093 54.26093681 189.5228758 107.9614281 0 0 110.5058801 180.1538584 53.99506613 161.0277834 0.372444864 0.336966303 1.176957614 0.670452178 0 0 0.686253501 1.118775 0.335315217 1 7.331165819 -5.965813868 24.99603952 0.705003591 0.42323686 0.043296398 0.400460943 368.6353647 269535.3464 0.063372164 0.114871423 1.08E-06 5.965813868 -0.281766731 GLS(ph)DHVSLDGQELGTR ddPTM_HeLa_Curcumin_4h_R1 1 GLSDHVSLDGQELGTR 16 0 Q7L8J4;Q7L8J4-2 Q7L8J4 SH3BP5L SH3 domain-binding protein 5-like 1 0 GLS(0.909)DHVS(0.091)LDGQELGTR 107.5 0.00085858 78142000 4435.4 3618.1 3147.4 3071.4 4913.1 7133.8 4429.6 4065.6 5502.3 3897.2 TRUE FALSE FALSE 4084.33341 3930.832442 3264.045413 3058.691361 4854.514491 5654.169466 4553.882654 5305.182724 4898.711456 4032.62741 1.012821914 0.97475716 0.809409122 0.758485982 1.203809328 1.402105598 1.129259461 1.315564813 1.214769171 1 11.9775044 -5.577947814 9.605965627 0.971893672 1.272989383 0.561693762 0.131361935 0.177634554 29.55702789 0.016287175 0.032617286 2.64E-06 5.577947814 0.301095711 GLS(ph)EDTTEETLK ddPTM_HeLa_Curcumin_4h_R1 1 GLSEDTTEETLK 12 0 P19338;H7BY16 P19338 NCL Nucleolin 1 0 GLS(0.999)EDT(0.001)TEETLK 134.56 0.0018838 3902700 1962.1 1575 1884.9 1669.6 2485.1 3486.4 2195.5 2188.5 1903.6 1909.3 TRUE FALSE FALSE 1806.797715 1711.135982 1954.756052 1662.691638 2455.466806 2763.28134 2257.099821 2855.763575 1694.779843 1975.648033 0.914534211 0.866113778 0.989425252 0.841593042 1.242866525 1.398670864 1.142460491 1.445481952 0.857834905 1 10.94811023 -5.658959056 5.508012198 0.946369844 1.310933185 0.811568369 0.092945316 0.064658402 2.954715484 0.012145051 0.024526458 2.19E-06 5.658959056 0.364563341 LLS(ph)SNEDDANILSS(ph)PTDR ddPTM_HeLa_Curcumin_4h_R1 1 LLSSNEDDANILSSPTDR 18 0 H0YEG1;F5GY88;A0A0B4J1W0;O75448-2;O75448 H0YEG1 MED24 Mediator of RNA polymerase II transcription subunit 24 2 0 LLS(0.894)S(0.106)NEDDANILS(0.253)S(0.62)PT(0.128)DR 93.551 0.0054485 4802100 520.54 353.43 475.67 470.4 327.16 651.37 609.34 3005.5 371.65 567.5 TRUE FALSE FALSE 479.3387097 383.9789143 493.2987486 468.4536094 323.2588307 516.2685195 626.4364404 3921.863114 330.8809248 587.2205828 0.816283904 0.653892124 0.840056979 0.797747257 0.550489612 0.879173065 1.066782158 6.678688094 0.563469562 1 9.197758727 -4.261026807 5.410912882 0.855149845 6.904217725 0.99219431 0.156555241 0.008528455 0.920911343 0.020875134 0.190379901 5.48E-05 4.261026807 6.04906788 up GLS(ph)EDVSISK ddPTM_HeLa_Curcumin_4h_R1 1 GLSEDVSISK 10 0 Q15029-3;Q15029;Q15029-2;K7EP67 Q15029-3 EFTUD2 116 kDa U5 small nuclear ribonucleoprotein component 1 0 GLS(0.689)EDVS(0.311)ISK 110.08 0.0075734 6392500 4361.5 3512.7 3401.1 4045.5 4410.2 2076.6 2550.5 2431.4 4582.3 3877.2 TRUE FALSE FALSE 4016.282673 3816.322136 3527.147758 4028.760793 4357.611245 1645.889752 2622.060166 3172.722667 4079.633154 4011.932411 1.001084331 0.951242879 0.879164302 1.004194583 1.086162676 0.410248624 0.653565389 0.790821565 1.016874846 1 11.97008159 -5.272886763 24.9999602 0.992623331 0.621747206 0.747846335 0.099253808 244.2880484 533501.1286 0.01354494 0.030532623 5.33E-06 5.272886763 -0.370876125 GLS(ph)PADVAQEHLK ddPTM_HeLa_Curcumin_4h_R1 1 GLSPADVAQEHLK 13 0 P10070 P10070 GLI2 Zinc finger protein GLI2 1 0 GLS(1)PADVAQEHLK 124.68 0.00098066 26004000 5000.9 4385.7 4831.9 4864.7 5138.2 7638.7 7207.6 5471.4 5260.2 4085.4 TRUE FALSE FALSE 4605.073488 4764.780366 5010.974465 4844.57116 5076.930321 6054.347514 7409.825858 7139.604673 4683.16922 4227.367346 1.08934784 1.127127116 1.185365277 1.146001935 1.200967388 1.432179184 1.752822798 1.688900937 1.107821686 1 12.04554377 -5.01866767 0.872656224 1.054123098 1.856900696 0.930227755 0.065471495 0.166065086 0.173376807 0.011358282 0.099151845 9.58E-06 5.01866767 0.802777598 GLS(ph)PAMS(ph)PALQR ddPTM_HeLa_Curcumin_4h_R1 4 GLSPAMSPALQR 12 0 Q96DF8 Q96DF8 DGCR14 Protein DGCR14 2 0 GLS(1)PAMS(1)PALQR;GLS(1)PAMS(1)PALQR;GLS(1)PAMS(1)PALQR;GLS(1)PAMS(1)PALQR ;;; 186.16 7.80E-05 19256000 15088.6 13526 13578.9 14325.9 14635.8 18104.8 13615.4 8440.3 16025.8 11852.3 TRUE FALSE FALSE 13894.32139 14695.12717 14082.14598 14266.62322 14461.27764 14349.6604 13997.41148 11013.70862 14267.80983 12264.16654 1.132920149 1.198216537 1.148235058 1.163277029 1.179148831 1.170047744 1.141325946 0.898039714 1.163373784 1 13.58216157 -8.98963496 0.868909181 1.002553258 1.13536674 0 0.094249728 0.580252407 0.820700299 0.046510245 0.015606937 1.02E-09 8.98963496 0.132813482 GLS(ph)SSEKDNIER ddPTM_HeLa_Curcumin_4h_R1 1 GLSSSEKDNIER 12 1 Q8IYH5-2;Q8IYH5;Q8IYH5-4 Q8IYH5-2 ZZZ3 ZZ-type zinc finger-containing protein 3 1 0 GLS(0.476)S(0.476)S(0.049)EKDNIER 167.22 0.0011884 5778300 1911.3 1530.4 1423.2 1602 1580.3 1799.6 1230.2 2360.7 2116.5 1763.7 TRUE FALSE FALSE 1760.018588 1662.680957 1475.945044 1595.371348 1561.455955 1426.342674 1264.716101 3080.466563 1884.325245 1824.988444 0.964399854 0.911063827 0.808742132 0.874181617 0.855597722 0.781562579 0.692999512 1.687937572 1.032513522 1 10.83367161 -4.250586177 24.78793554 0.922713124 1.687938064 0.835471197 0.106039583 483.6084322 1104503.518 0.016466572 0.324768151 5.62E-05 4.250586177 0.765224939 ESEPAPAS(ph)VTALTDAR ddPTM_HeLa_Curcumin_4h_R1 1 ESEPAPASVTALTDAR 16 0 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 0 ESEPAPAS(0.997)VT(0.003)ALTDAR 220.27 1.92E-15 6682400 327.87 382.47 313.86 188.32 331.09 644.75 447.8 4076.6 447.56 335.37 TRUE FALSE FALSE 301.9187435 415.5290025 325.4919277 187.5407817 327.141968 511.0215822 460.3640628 5319.536574 398.4637877 347.0240825 0.870022453 1.197406818 0.937951987 0.540425841 0.942706816 1.472582474 1.326605518 15.32901272 1.148230938 1 8.438891975 -4.261023431 5.978785488 0.969914226 15.72439932 0.997100609 0.231065481 0.004821001 0.815577779 0.033144339 0.287370721 5.48E-05 4.261023431 14.75448509 up GLSAS(ph)LPDLDSENWIEVK ddPTM_HeLa_Curcumin_4h_R1 4 GLSASLPDLDSENWIEVK 18 0 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50;H0YBW1;H0YC73 Q6PKG0 LARP1 La-related protein 1 1 0 GLS(0.071)AS(0.928)LPDLDSENWIEVK;GLS(0.028)AS(0.972)LPDLDSENWIEVK;GLS(0.011)AS(0.926)LPDLDS(0.063)ENWIEVK;GLSAS(0.935)LPDLDS(0.065)ENWIEVK ;;; 208.43 2.78E-14 32942600 20773.9 17679.14 19558.7 20343 18476.5 22302 18014.84 16525.11 24168.3 20550.1 TRUE FALSE FALSE 19129.62389 19207.24608 20283.56263 20258.82606 18256.1798 17676.3138 18520.28793 21563.53997 21517.09796 21264.21445 0.899615828 0.903266196 0.953882528 0.952719232 0.858540053 0.831270483 0.870960363 1.014076491 1.011892445 1 14.37613994 -9.481435843 0.552418477 1.024724736 0.904341392 0.358409354 0.05049307 1.54689083 0.579118083 0.101251502 0.012292428 3.30E-10 9.481435843 -0.120383344 GLSAS(ph)LPDLDSENWIEVKK ddPTM_HeLa_Curcumin_4h_R1 1 GLSASLPDLDSENWIEVKK 19 1 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50;H0YBW1;H0YC73 Q6PKG0 LARP1 La-related protein 1 1 0 GLS(0.033)AS(0.913)LPDLDS(0.054)ENWIEVKK 107.21 0.00028019 101060000 2699.8 1783.3 1491.7 2277.6 1716.8 2761.6 2148.8 1625.3 3032.8 2522.1 TRUE FALSE FALSE 2486.107981 1937.440506 1546.983714 2268.175895 1696.328281 2188.81303 2209.089545 2120.846488 2700.109428 2609.742787 0.952625674 0.742387532 0.592772484 0.869118561 0.649998264 0.838708336 0.846477881 0.812664949 1.034626646 1 11.34969191 -7.313950013 4.973343758 0.978928274 0.763502057 0.606431324 0.085140879 0.105514708 5.773094162 0.01420454 0.01631654 4.85E-08 7.313950013 -0.215426217 GLSASLPDLDS(ph)ENWIEVKK ddPTM_HeLa_Curcumin_4h_R1 1 GLSASLPDLDSENWIEVKK 19 1 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50;H0YBW1;H0YC73 Q6PKG0 LARP1 La-related protein 1 1 0 GLS(0.017)AS(0.131)LPDLDS(0.852)ENWIEVKK 61.52 0.0094963 117680000 1900.7 1157.1 1230.6 1290.4 1091.3 1583.6 1386.4 1247.2 1977.9 1768.9 TRUE FALSE FALSE 1750.257589 1257.114568 1276.207119 1285.060667 1078.28696 1255.143509 1425.298653 1627.465539 1760.929318 1830.369143 0.956232023 0.68680931 0.697240293 0.702077322 0.589109013 0.685732446 0.778694646 0.889146074 0.962062393 1 10.83791892 -7.297191107 5.625726399 0.980279107 0.712856933 0.716560889 0.073246963 0.073466754 6.613180752 0.013187012 0.015208474 5.04E-08 7.297191107 -0.267422174 GLSAST(ph)MDLSSSS ddPTM_HeLa_Curcumin_4h_R1 1 GLSASTMDLSSSS 13 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 0 GLS(0.002)AS(0.086)T(0.912)MDLSSSS 131.12 0.0045735 8065900 2463.2 2048.4 2410.2 2276.7 2185 3519.1 2578.8 2143.6 2463.7 2653.7 TRUE FALSE FALSE 2268.235121 2225.454569 2499.524132 2267.279619 2158.945302 2789.198992 2651.154188 2797.173772 2193.438274 2745.915877 0.826039552 0.810459849 0.91026974 0.82569158 0.78623869 1.015762724 0.965489952 1.018666957 0.798800244 1 11.42307171 -5.21925038 24.97475152 0.892559831 0.996524926 0.41097459 0.070293911 556.1636021 329233.1791 0.012081431 0.030801386 6.04E-06 5.21925038 0.103965095 GLSDHVS(ph)LDGQELGTR ddPTM_HeLa_Curcumin_4h_R1 1 GLSDHVSLDGQELGTR 16 0 Q7L8J4;Q7L8J4-2 Q7L8J4 SH3BP5L SH3 domain-binding protein 5-like 1 0 GLS(0.001)DHVS(0.999)LDGQELGTR 88.282 0.0032815 25392000 5098.5 4596.4 3836.6 3555.9 5861.3 9796.6 5455.4 4434.7 6839 4480.5 TRUE FALSE FALSE 4694.948345 4993.692335 3978.787771 3541.186628 5791.407826 7764.67473 5608.463842 5786.819615 6088.77881 4636.197042 1.012672305 1.077109599 0.858200748 0.763812797 1.249172064 1.674793944 1.209712139 1.248182414 1.313313208 1 12.17872617 -5.557281145 9.314525825 0.985258785 1.377595622 0.478724154 0.17761855 0.150213649 38.55935302 0.020521282 0.041200652 2.77E-06 5.557281145 0.392336836 GLSEDTTEETLK ddPTM_HeLa_Curcumin_4h_R1 2 GLSEDTTEETLK 12 0 P19338;H7BY16 P19338 NCL Nucleolin 0 0 ; ; 212.28 3.87E-21 8542500 3543.3 3681 3743.9 3749.8 3727.2 3907.1 4134.9 2865.8 3510.2 3557.1 FALSE FALSE TRUE 3262.844066 3999.169238 3882.652227 3734.284321 3682.755574 3096.723418 4250.914165 3739.569227 3125.139842 3680.70896 0.886471629 1.08652145 1.054865318 1.014555718 1.000556038 0.841338843 1.154917221 1.015991557 0.84905921 1 11.84576796 -7.26354861 24.99888954 0.946389381 1.022018137 0.24085708 0.084874508 272.1066434 3225040.955 0.014138033 0.016605225 5.45E-08 7.26354861 0.075628755 GLSEDTTEETLKESFDGSVR ddPTM_HeLa_Curcumin_4h_R1 2 GLSEDTTEETLKESFDGSVR 20 1 P19338;H7BY16 P19338 NCL Nucleolin 0 0 ; ; 163 5.29E-06 65100000 2927.3 2405.7 2715 2672.3 2698 3295.3 2782.7 2976.4 3235.4 2629.5 FALSE FALSE TRUE 2695.601116 2613.637988 2815.620288 2661.242731 2665.828112 2611.817634 2860.775073 3883.890658 2880.484715 2720.874929 0.990711145 0.960587332 1.034821652 0.978083447 0.979768707 0.959918299 1.051417337 1.427441819 1.058661199 1 11.40985493 -4.264754265 3.389367043 0.991659801 1.48239745 0.949451664 0.029712858 0.029832909 0.570635688 0.002731597 0.037594305 5.44E-05 4.264754265 0.490737649 GLSTS(ph)LPDLDSEPWIEVK ddPTM_HeLa_Curcumin_4h_R1 1 GLSTSLPDLDSEPWIEVK 18 0 H0Y9K3;D6R9W6;D6RJB0;A0A3B3ISF0;Q659C4-9;Q659C4-2;Q659C4;Q659C4-4 H0Y9K3 LARP1B La-related protein 1B 1 0 GLS(0.027)T(0.146)S(0.827)LPDLDSEPWIEVK 136.26 0.00028508 979010 673.81 526.75 640.82 677.51 702.79 549.24 439.84 493.18 459.87 620.7 TRUE FALSE FALSE 620.4772275 572.2799228 664.5693529 674.7066431 694.4096883 435.3214328 452.1807266 643.5483117 409.4234115 642.2692788 0.966070226 0.891028019 1.034720755 1.050504306 1.08118154 0.677786479 0.704036051 1.001991428 0.637463794 1 9.32703448 -5.264436966 24.99993841 0.991111943 0.785547792 0.159012722 0.146436382 155.7989389 1299372.648 0.012917446 0.030101074 5.44E-06 5.264436966 -0.205564151 GLTLAPGLS(ph)PARPLFGSDFEK ddPTM_HeLa_Curcumin_4h_R1 2 GLTLAPGLSPARPLFGSDFEK 21 1 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 0 GLTLAPGLS(1)PARPLFGSDFEK;GLT(0.001)LAPGLS(0.999)PARPLFGSDFEK ; 93.712 0.00015861 65364000 5305.7 3368.6 5181.9 4330 4774.5 5991.4 3929.6 1996.27 4273.3 3205.5 TRUE FALSE FALSE 4885.748246 3659.766774 5373.945772 4312.083607 4717.567206 4748.716103 4039.854 2604.923533 3804.529681 3316.890886 1.472990344 1.103372676 1.620175627 1.300037823 1.42228592 1.431676912 1.217964093 0.785350988 1.147016833 1 11.69561584 -2.93012536 11.04995841 1.253934991 1.259069584 0 0.237407983 0 0 0.033927329 0 0.001174558 2.93012536 0.005134594 GLTPSQIGVILR ddPTM_HeLa_Curcumin_4h_R1 2 GLTPSQIGVILR 12 0 P62277;J3KMX5 P62277 RPS13 40S ribosomal protein S13 0 0 ; ; 128.01 0.00052295 3899500 2114.47 1883.03 1953.29 2214 1915.7 2051.23 1904.18 1682.3 2181.37 1601.22 FALSE FALSE TRUE 1947.107468 2045.790723 2025.680646 2204.839055 1892.856529 1625.781776 1957.606166 2195.225526 1942.079169 1656.862276 1.175177621 1.234737946 1.222600499 1.330731641 1.142434441 0.98124135 1.181514115 1.324929391 1.172142789 1 10.69423797 -8.858843888 0.761005419 1.001487799 1.195943892 0.071256561 0.106367109 0.565077984 0.618348498 0.061068061 0.021004363 1.38E-09 8.858843888 0.194456094 GLTSVINQK ddPTM_HeLa_Curcumin_4h_R1 2 GLTSVINQK 9 0 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 0 ; ; 157.91 4.01E-08 52075000 9179.1 7907.6 9207.7 9028.5 8543.7 10917.8 7455.9 8259.6 9627.6 9497.6 FALSE FALSE TRUE 8452.564549 8591.097708 9548.945462 8991.142459 8441.821958 8653.325211 7665.092487 10777.91402 8571.476367 9827.640893 0.86008073 0.874177008 0.971641675 0.914883089 0.85898763 0.880508894 0.779952439 1.09669392 0.872180461 1 13.26262943 -9.431231391 1.129839344 1.000705028 0.896164633 0 0.088500892 0.632921422 1.429694156 0.052447907 0.012802877 3.70E-10 9.431231391 -0.104540395 GLTTTGNSS(ph)LNSTSNTK ddPTM_HeLa_Curcumin_4h_R1 1 GLTTTGNSSLNSTSNTK 17 0 Q96KR1 Q96KR1 ZFR Zinc finger RNA-binding protein 1 0 GLTTTGNS(0.026)S(0.701)LNS(0.21)T(0.063)S(0.001)NTK 172.42 4.61E-18 0 539.84 540.97 587.14 611.44 872.76 921.75 842.53 494.03 718.07 606.69 TRUE FALSE FALSE 497.1110944 587.7290363 608.8999249 608.9100233 862.352907 730.5686597 866.1691242 644.6574728 639.2995175 627.7724323 0.791865123 0.936213516 0.969937343 0.969953429 1.373671195 1.163747597 1.379750176 1.026896754 1.018361885 1 9.294097866 -5.88351443 5.74563073 0.909653005 1.23989046 0.602823069 0.112942973 0.097437098 4.557379995 0.017001726 0.031181687 1.31E-06 5.88351443 0.330237456 GLVAAYS(ph)GDS(ph)DNEEELVER ddPTM_HeLa_Curcumin_4h_R1 3 GLVAAYSGDSDNEEELVER 19 0 P52756 P52756 RBM5 RNA-binding protein 5 2 0 GLVAAY(0.006)S(0.995)GDS(1)DNEEELVER;GLVAAY(0.148)S(0.853)GDS(0.999)DNEEELVER;GLVAAY(0.366)S(0.77)GDS(0.865)DNEEELVER ;; 142.91 6.22E-07 3024400 4997 3776.01 3797 4803.74 4660.86 4159.6 3135.51 3119.93 4258.32 4243.22 TRUE FALSE FALSE 4601.482177 4102.391479 3937.72016 4783.863397 4605.282289 3296.852072 3223.483972 4071.182295 3791.19295 4390.671579 1.048013292 0.934342595 0.896837782 1.089551635 1.048878789 0.750876492 0.734166497 0.927234529 0.863465391 1 12.10022591 -5.2631579 24.99917249 1.01334238 0.797099899 0.451190217 0.08588389 68.49523376 996402.7267 0.010168289 0.023896133 5.46E-06 5.2631579 -0.216242481 GLVAAYSGDS(ph)DNEEELVER ddPTM_HeLa_Curcumin_4h_R1 4 GLVAAYSGDSDNEEELVER 19 0 P52756 P52756 RBM5 RNA-binding protein 5 1 0 GLVAAYS(0.001)GDS(0.999)DNEEELVER;GLVAAY(0.002)S(0.057)GDS(0.941)DNEEELVER;GLVAAYSGDS(1)DNEEELVER;GLVAAYS(0.314)GDS(0.686)DNEEELVER ;;; 274.68 1.57E-68 462050200 9488.27 8460.53 8718.01 8618.97 9855.5 9546.87 8740.43 6396.35 8337.3 7859.42 TRUE FALSE FALSE 8737.263418 9191.820514 9041.10712 8583.306986 9737.979599 7566.741547 8985.662942 8346.56767 7422.719049 8132.53426 1.074359251 1.13025291 1.111720754 1.055428322 1.197410215 0.930428487 1.104903177 1.026318169 0.912719063 1 12.98948928 -8.879387201 0.912421276 1.003628591 1.079664935 0.264206423 0.07259895 0.703938727 1.137674848 0.031320755 0.012309431 1.32E-09 8.879387201 0.076036344 GLVAAYSGDS(ph)DNEEELVERLESEEEK ddPTM_HeLa_Curcumin_4h_R1 1 GLVAAYSGDSDNEEELVERLESEEEK 26 1 P52756 P52756 RBM5 RNA-binding protein 5 1 0 GLVAAY(0.044)S(0.231)GDS(0.725)DNEEELVERLESEEEK 77.53 7.43E-05 3840100 536.5 397.73 553.98 337.51 433.07 607.14 586.2 332.31 599.06 649.94 TRUE FALSE FALSE 494.0354589 432.1080089 574.5109861 336.113473 427.9059231 481.2123201 602.6471943 433.6297892 533.3446168 672.5253666 0.734597509 0.642515555 0.854259207 0.499778134 0.636267336 0.715530364 0.896095856 0.64477834 0.793047583 1 9.393444875 -8.915612539 0.641304221 1.014412367 0.698860338 0.22082987 0.123412298 0.524956781 0.382381904 0.088292667 0.02465218 1.21E-09 8.915612539 -0.315552029 EVAATEEDVTRLPS(ph)PT(ph)SPFSSLSQDQAATSK ddPTM_HeLa_Curcumin_4h_R1 2 EVAATEEDVTRLPSPTSPFSSLSQDQAATSK 31 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424 Q8WWI1-3 LMO7 LIM domain only protein 7 2 0 EVAATEEDVT(0.007)RLPS(0.801)PT(0.525)S(0.525)PFS(0.088)S(0.035)LS(0.019)QDQAATSK;EVAAT(0.003)EEDVT(0.003)RLPS(0.629)PT(0.629)S(0.629)PFS(0.065)S(0.025)LS(0.015)QDQAAT(0.002)S(0.001)K ; 91.249 9.81E-08 43192400 5226.3 4156.3 4644.1 4437.4 4276.4 5394.7 5380.6 11577.3 5401.6 4589.9 TRUE FALSE FALSE 4812.63284 4515.552052 4816.214431 4419.039215 4225.406723 4275.778409 5531.565155 15107.16547 4809.057994 4749.398683 1.01331414 0.950762897 1.014068254 0.930441833 0.889671936 0.900277844 1.164687474 3.180858564 1.012561445 1 12.21352915 -4.26101592 4.120769677 0.9843829 3.36547501 0.994711764 0.048183412 0.012071986 0.444739175 0.007490468 0.084933959 5.48E-05 4.26101592 2.38109211 up GLVAAYSGES(ph)DS(ph)EEEQERGGPEREEK ddPTM_HeLa_Curcumin_4h_R1 1 GLVAAYSGESDSEEEQERGGPEREEK 26 2 P98175-5;P98175-2;P98175;P98175-4;P98175-3 P98175-5 RBM10 RNA-binding protein 10 2 0 GLVAAY(0.136)S(0.381)GES(0.864)DS(0.619)EEEQERGGPEREEK 62.823 0.0019478 14735000 5815.3 3944.6 3862.4 4430.9 3673.4 6063.9 5193.1 7153.1 6288.2 5442 TRUE FALSE FALSE 5355.012869 4285.553647 4005.543942 4412.56611 3629.597104 4806.178786 5338.804409 9334.047261 5598.400192 5631.109095 0.950969477 0.761049657 0.711324159 0.783605154 0.644561674 0.853504826 0.948091099 1.65758594 0.994191392 1 12.45920339 -4.262068251 4.57277713 0.897850413 1.705634808 0.785649654 0.124599896 0.08298482 4.506273393 0.021069993 0.214352532 5.47E-05 4.262068251 0.807784394 GLVAAYSGES(ph)DSEEEQER ddPTM_HeLa_Curcumin_4h_R1 1 GLVAAYSGESDSEEEQER 18 0 P98175-5;P98175-2;P98175;P98175-4;P98175-3 P98175-5 RBM10 RNA-binding protein 10 1 0 GLVAAYS(0.394)GES(0.597)DS(0.009)EEEQER 178.14 9.07E-07 5345800 641.52 521.26 432.08 529.24 612.13 694.69 706.33 1076.8 652.14 734.78 TRUE FALSE FALSE 590.7430151 566.3153917 448.0932649 527.0501451 604.8307495 550.6034632 726.1477188 1405.111363 580.6018736 760.3135503 0.776972888 0.744844534 0.589353254 0.693201042 0.795501736 0.724179469 0.955063498 1.84806829 0.763634784 1 9.570450693 -4.266669293 3.672767315 0.829419081 1.95409392 0.884889087 0.115034319 0.083976614 2.088123569 0.020782605 0.255174109 5.41E-05 4.266669293 1.124674839 SISLSQS(ph)AENVPASK ddPTM_HeLa_Curcumin_4h_R1 1 SISLSQSAENVPASK 15 0 H0YFN7;Q4ADV7-2;Q4ADV7-3;Q4ADV7 H0YFN7 RIC1 RAB6A-GEF complex partner protein 1 1 0 S(0.113)IS(0.213)LS(0.155)QS(0.297)AENVPAS(0.223)K 102.63 0.0030601 12513000 2211.5 1728.3 2155.4 2712.2 2184 2697.5 2451.9 5733.4 1808.8 2352.9 TRUE FALSE FALSE 2036.457441 1877.686551 2235.28102 2700.977635 2157.957226 2138.008093 2520.693715 7481.487267 1610.379165 2434.6631 0.836443219 0.771230546 0.918106912 1.109384553 0.886347366 0.87815357 1.035335737 3.072904529 0.661438195 1 11.24950644 -4.260994083 4.792836853 0.919274035 3.193852273 0.968020639 0.11864234 0.017669285 1.152363008 0.013495603 0.133652288 5.48E-05 4.260994083 2.274578238 up GLVGEIIK ddPTM_HeLa_Curcumin_4h_R1 1 GLVGEIIK 8 0 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;E5RHP0;F6XY72;C9K028;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 0 113.5 0.0045584 6301800 4521.4 2867.5 3990.3 3942.7 3863.2 4205.2 3918.5 3838.8 3538.1 3288.4 FALSE FALSE TRUE 4163.526419 3115.353923 4138.184028 3926.386152 3817.133863 3332.994118 4028.442564 5009.232448 3149.979282 3402.671655 1.223605108 0.915561135 1.216157316 1.153912734 1.121804937 0.979522697 1.183905758 1.472146876 0.925737068 1 11.73245223 -1.000005835 0.017626215 1.65E-06 2.584309821 0.266130659 0.138897157 5315.410048 7.301086492 412.7659887 691.7258153 0.099998656 1.000005835 2.584308171 GLVGEIIK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GLVGEIIKR 9 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;E5RHP0;F6XY72;C9K028;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 1 ; GLVGEIIK(1)R;GLVGEIIK(1)R 130.75 0.00019531 51585000 5507 7740.8 4975.1 5700.8 10803.8 14196.1 11178.8 10561.1 14108.7 6074.3 FALSE TRUE FALSE 5071.115139 8409.88026 5159.481583 5677.2116 10674.97174 11251.66884 11492.44704 13781.13077 12561.01091 6285.381473 0.806811036 1.33800634 0.820870078 0.903240579 1.698380884 1.790133007 1.828440659 2.192568714 1.998448457 1 12.61778459 -5.674342305 3.429640928 0.932861678 1.906956929 0.421528312 0.379888982 0.060777017 1.411384292 0.026482491 0.05515371 2.12E-06 5.674342305 0.974095252 GLVGEIIKR ddPTM_HeLa_Curcumin_4h_R1 3 GLVGEIIKR 9 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;E5RHP0;F6XY72;C9K028;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 0 ;; ;; 124.08 0.0075881 83071000 18788.2 14704.4 14975.8 15690.7 16474.8 20902.1 16682.2 15980.9 19548.8 17306.1 FALSE FALSE TRUE 17301.09414 15975.38281 15530.81632 15625.77604 16278.34877 16566.76884 17150.25763 20853.40284 17404.34555 17907.48569 0.966137539 0.892106413 0.867280678 0.872583472 0.90902481 0.925130928 0.95771444 1.164507581 0.971903362 1 14.12827517 -4.26204743 6.254468732 0.951963382 1.169378945 0.667409894 0.04746137 0.07705257 16.22679153 0.008452521 0.070884107 5.47E-05 4.26204743 0.217415562 GLVGPELHDR ddPTM_HeLa_Curcumin_4h_R1 3 GLVGPELHDR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ;; ;; 140.16 1.91E-05 21052700 10657.5 8628.1 9678.4 10053.7 10095 11534.5 9251.3 7841.9 11337.7 10691.4 FALSE FALSE TRUE 9813.947629 9373.874518 10037.09002 10012.10045 9974.623718 9142.114679 9510.866579 10232.85921 10093.98268 11062.92535 0.8871024 0.847323309 0.907272688 0.905013831 0.901626233 0.826374073 0.859706296 0.924968657 0.912415329 1 13.43344531 -9.077924675 0.625634712 1.011057086 0.878976824 0.252241545 0.039403893 0.418831477 0.266466501 0.030189521 0.006814256 8.36E-10 9.077924675 -0.132080262 GLVLDHGAR ddPTM_HeLa_Curcumin_4h_R1 3 GLVLDHGAR 9 0 P40227;P40227-2 P40227 CCT6A T-complex protein 1 subunit zeta 0 0 ;; ;; 154.12 0.0010783 20853000 11721.4 8019.4 10263.6 8850.8 9962.4 15771.7 11074.9 12786.1 11670 10671 FALSE FALSE TRUE 10793.63882 8712.561202 10643.97804 8814.177735 9843.604887 12500.47164 11385.63189 16684.52303 10389.8302 11041.81646 0.97752384 0.789051443 0.96396984 0.798254324 0.891484198 1.132102828 1.031137579 1.511030644 0.940952989 1 13.4306899 -3.237035278 1.132293712 0.955811425 5.5717073 0.775261942 0.092620445 5.2106563 0.901682755 0.014404327 49.17321275 0.000579382 3.237035278 4.615895875 GLVPEDDTK(ac)EK ddPTM_HeLa_Curcumin_4h_R1 1 GLVPEDDTKEK 11 1 Q15459;Q15459-2;H7C1L2 Q15459 SF3A1 Splicing factor 3A subunit 1 0 1 GLVPEDDTK(1)EK 108.43 0.0050196 1981600 1195.5 1418.4 938.43 1019.8 1886 2230.8 1922.9 2020.5 2549.3 1267.3 FALSE TRUE FALSE 1100.874914 1541.000176 973.2090413 1015.580338 1863.510682 1768.106934 1976.851399 2636.541149 2269.648168 1311.338581 0.839504709 1.175135238 0.742149324 0.774460809 1.421075159 1.34832221 1.507506473 2.010572393 1.730787305 1 10.35682451 -4.449441814 0.727682784 0.920077345 2.422377013 0.425241395 0.306577034 0.700639722 0.304687405 0.028619645 0.812776134 3.55E-05 4.449441814 1.502299668 GLVSDGTS(ph)PGER ddPTM_HeLa_Curcumin_4h_R1 2 GLVSDGTSPGER 12 0 Q9NRF2-3;Q9NRF2-2;Q9NRF2 Q9NRF2-3 SH2B1 SH2B adapter protein 1 1 0 GLVSDGT(0.036)S(0.964)PGER;GLVSDGT(0.232)S(0.768)PGER ; 133.88 0.001972 42282000 10011.9 8566 9250.4 9053.1 9356.9 13115.9 10861 4647.5 10194.2 8049.5 TRUE FALSE FALSE 9219.44755 9306.406871 9593.227961 9015.640671 9245.325079 10395.51449 11165.73043 6064.501356 9075.921765 8329.219526 1.106880125 1.117320397 1.151755928 1.08241122 1.109986962 1.248077861 1.340549423 0.728099594 1.089648524 1 13.0239656 -8.8366715 0.601960574 0.993601507 1.126982413 0.008553166 0.151525134 1.722765571 1.126704687 0.117513933 0.034138362 1.46E-09 8.8366715 0.133380906 GLVYETSVLDPDEGIR ddPTM_HeLa_Curcumin_4h_R1 2 GLVYETSVLDPDEGIR 16 0 F8W642;F8VZK9;F8VX07;F8VRP1;F8VX68;F8VPF9;F8VPA1;F8VTT8;F8W1S4;F8W4S1;H0YH82;A0A0C4DGI3;B4DJV2;O75390 F8W642 CS "Citrate synthase;Citrate synthase, mitochondrial" 0 0 ; ; 185.3 5.48E-05 6827800 2556 1608.51 2121.7 2352 2671.7 3386.5 2481.7 2061.71 2983.9 1969.7 FALSE FALSE TRUE 2353.689903 1747.542437 2200.332068 2342.268047 2639.841722 2684.101726 2551.329823 2690.315888 2656.573635 2038.146928 1.154818561 0.8574173 1.079574803 1.149214522 1.295216594 1.3169324 1.25178896 1.319981327 1.303425969 1 10.99304234 -5.941941419 2.602928568 1.056230882 1.296049805 0.466019122 0.108292932 0.138852254 1.906684348 0.013208448 0.025426675 1.14E-06 5.941941419 0.239818923 GLWHEEMK ddPTM_HeLa_Curcumin_4h_R1 1 GLWHEEMK 8 0 E9PL69;P23921 E9PL69 RRM1 Ribonucleoside-diphosphate reductase large subunit 0 0 96.19 0.013795 13700000 5763.4 4643.8 5125 5145.3 5287.9 5798.6 4644.6 4617 4765.6 5442.9 FALSE FALSE TRUE 5307.220808 5045.18938 5314.937008 5124.010112 5224.845246 4595.904996 4774.914976 6024.702046 4242.825603 5632.04037 0.942326486 0.895801352 0.94369654 0.90979641 0.927700248 0.816028419 0.847812633 1.069719258 0.753337214 1 12.45944196 -8.222326343 0.563902661 0.999230103 0.906745162 0 0.099351659 0.862714862 0.612426078 0.034839402 0.018106677 5.99E-09 8.222326343 -0.092484941 GLWSTDS(ph)AEEDKETK ddPTM_HeLa_Curcumin_4h_R1 1 GLWSTDSAEEDKETK 15 1 Q99549-2;Q99549;A0A0A0MT47 Q99549-2 MPHOSPH8 M-phase phosphoprotein 8 1 0 GLWSTDS(1)AEEDKETK 218.21 2.20E-13 21013000 1916.1 1134.8 1775.7 1904.9 1939.4 1872.5 2104.1 1099.9 2062.2 1934.3 TRUE FALSE FALSE 1764.438663 1232.887055 1841.509004 1897.018029 1916.273922 1484.122393 2163.135383 1435.254447 1835.981819 2001.516781 0.881550772 0.615976377 0.92005674 0.947790219 0.95741087 0.741498851 1.080748062 0.717083394 0.917295242 1 10.966878 -8.743265508 1.064795895 0.988197031 0.865226737 0.074432131 0.130385847 0.677233207 1.535609094 0.047454552 0.023610112 1.81E-09 8.743265508 -0.122970294 GLYDGPVCEVSVT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 GLYDGPVCEVSVTPK 15 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 0 GLYDGPVCEVS(0.019)VT(0.981)PK;GLYDGPVCEVS(0.011)VT(0.989)PK ; 171.08 4.98E-06 10315000 3828.6 3207 3325.1 3909 3814.2 4703.8 3630.7 3158.7 4275.5 3847.5 TRUE FALSE FALSE 3525.56227 3484.19879 3448.331131 3892.825594 3768.718156 3728.178857 3732.56767 4121.773089 3806.488347 3981.200339 0.88555259 0.875162889 0.866153632 0.977801985 0.946628613 0.936445931 0.937548315 1.035309138 0.95611575 1 11.95898776 GLYDGPVCEVSVTPK ddPTM_HeLa_Curcumin_4h_R1 1 GLYDGPVCEVSVTPK 15 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 0 0 140.91 1.72E-15 0 70.848 0 0 67.981 159.51 220.28 0 0 0 0 FALSE FALSE TRUE 65.24030604 0 0 67.69971263 157.6079474 174.5914449 0 0 0 0 0 GMDDDRGPR ddPTM_HeLa_Curcumin_4h_R1 2 GMDDDRGPR 9 1 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 ; ; 104.06 0.0095455 26902000 6989.3 6328.2 6203.3 6811.5 6249.1 6606.4 5252.6 5116.4 6710.1 6177.9 FALSE FALSE TRUE 6436.08953 6875.18141 6433.199755 6783.315818 6174.583564 5236.158171 5399.973819 6676.366807 5974.018818 6392.581565 1.006806009 1.075493733 1.006353957 1.061123077 0.965898284 0.819099157 0.844725056 1.044392901 0.934523675 1 12.64218295 -5.515458478 22.67749652 1.013205803 0.89619779 0.364391979 0.065714884 67.05514337 204929.3184 0.008321014 0.017260682 3.05E-06 5.515458478 -0.117008012 LTLTNLISLNEREEALT(ph)T(ph)NVWIEMQWCDYR ddPTM_HeLa_Curcumin_4h_R1 1 LTLTNLISLNEREEALTTNVWIEMQWCDYR 30 1 P07510-2;P07510 P07510-2 CHRNG Acetylcholine receptor subunit gamma 2 0 LTLT(0.002)NLIS(0.006)LNEREEALT(0.994)T(0.994)NVWIEMQWCDY(0.005)R 55.985 0.0014258 11632000 4057.5 3161.7 3030.7 3311.5 2699.6 3005 1980.9 700.53 3918.2 3488.3 TRUE FALSE FALSE 3736.344594 3434.98326 3143.020408 3297.79789 2667.409033 2381.729127 2036.478723 914.1183722 3488.383263 3609.518165 1.035136664 0.951645927 0.870758994 0.913639367 0.738993104 0.659846832 0.564196834 0.253252188 0.966440146 1 11.81759055 -4.569638965 0.543887805 1.017521656 5.43E-18 0.954486166 0.049648943 0.370226824 0.090495699 0.00944037 0.222547621 2.69E-05 4.569638965 -1.017521656 down GMFTKK(ac)LGNTNK(ac)NK ddPTM_HeLa_Curcumin_4h_R1 3 GMFTKKLGNTNKNK 14 3 A0A3B3ISZ1;Q8NB66 A0A3B3ISZ1 UNC13C Protein unc-13 homolog C 0 2 ;; GMFTK(0.028)K(0.972)LGNTNK(1)NK;GMFTK(0.124)K(0.876)LGNTNK(1)NK;GMFTK(0.001)K(0.999)LGNTNK(1)NK 144.17 0.00015975 7422000 3938.19 4063.98 3560.79 3321.9 3340.15 5017.1 2755.48 1472.29 3735.28 3771.6 FALSE TRUE FALSE 3626.478106 4415.252322 3692.75601 3308.154858 3300.320893 3976.496906 2832.791353 1921.184443 3325.529129 3902.662819 0.929231726 1.131343528 0.946214465 0.847666071 0.845658732 1.0189189 0.725861158 0.492275283 0.852117973 1 11.93024311 -4.484464676 2.535047527 0.96229089 0.47892626 0.726065305 0.087698312 0.119807152 1.284028083 0.011612259 0.099285851 3.28E-05 4.484464676 -0.48336463 GMGPGT(ph)PAGYGR ddPTM_HeLa_Curcumin_4h_R1 1 GMGPGTPAGYGR 12 0 P23246 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 1 0 GMGPGT(1)PAGYGR 118.77 0.010702 20644000 1030.3 709.03 890.52 1003 1113.4 1532.9 1291.3 515.94 1159.9 824.76 TRUE FALSE FALSE 948.7506678 770.3153938 923.5234546 998.8498518 1100.123432 1214.959261 1327.530403 673.2477309 1032.661872 853.4203486 1.111703827 0.902621311 1.082143701 1.170407822 1.289075699 1.423635214 1.55554107 0.788881742 1.210027243 1 9.7371127 -6.039532377 2.426926189 1.042060928 1.296018646 0.178838893 0.199103807 0.286325908 3.350951384 0.027807257 0.0518133 9.13E-07 6.039532377 0.253957718 GMKVHLTQHSGK ddPTM_HeLa_Curcumin_4h_R1 1 GMKVHLTQHSGK 12 1 Q6IV72 Q6IV72 ZNF425 Zinc finger protein 425 0 0 41.164 0.017808 7092300 12278 9492.2 11583 12164 9368.9 8974.6 8469.3 9738 11105 10812 FALSE FALSE TRUE 11306.18334 10312.66347 12012.27617 12113.66859 9257.181987 7113.166795 8706.925764 12707.07137 9886.809283 11187.7162 1.010589038 0.921784508 1.073702261 1.082765095 0.827441618 0.635801505 0.778257654 1.13580566 0.883720065 1 13.44962794 -5.7457669 24.60032784 1.0087676 0.824712656 0.237440613 0.129463152 171.9173629 269848.3168 0.017225891 0.034352051 1.80E-06 5.7457669 -0.184054944 GMLS(ph)S(ph)VDIDIY(ph)LLEK ddPTM_HeLa_Curcumin_4h_R1 1 GMLSSVDIDIYLLEK 15 0 Q9Y2K3 Q9Y2K3 MYH15 Myosin-15 3 0 GMLS(1)S(1)VDIDIY(1)LLEK 67.275 0.0074783 0 928.32 964.83 1157.7 954.82 879.94 1100.4 838.01 493.48 758.75 838.86 TRUE FALSE FALSE 854.8424924 1048.225606 1200.60538 950.8692078 869.4472902 872.1646359 861.5223052 643.9397803 675.5170233 868.0103226 0.984829869 1.207618825 1.383169473 1.09545841 1.001655473 1.004786018 0.992525415 0.741857284 0.778236163 1 9.761568389 -3.784527006 1.349426923 1.046292392 0.142396561 0.284621334 0.149290404 4.12827831 2.704258985 0.020755763 7.000872842 0.000164238 3.784527006 -0.903895831 GMYDGPVFDLT(ph)TTPKGGT(ph)PAGSAR ddPTM_HeLa_Curcumin_4h_R1 1 GMYDGPVFDLTTTPKGGTPAGSAR 24 1 Q14195-2;Q14195;H0YBT4 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 2 0 GMY(0.071)DGPVFDLT(0.337)T(0.362)T(0.362)PKGGT(0.862)PAGS(0.006)AR 49.433 0.008825 38907000 2020.5 1561.6 1379.9 1673.2 1306.4 2288.4 1933.7 1285.1 2122.3 2069.8 TRUE FALSE FALSE 1860.575293 1696.577746 1431.040308 1666.276742 1290.822033 1813.760044 1987.954418 1676.921074 1889.489 2141.725396 0.868727287 0.792154657 0.668171704 0.778006716 0.602701932 0.846868627 0.92820229 0.782976696 0.88222748 1 11.0645578 -7.945582763 0.931083221 0.974213345 0.770958692 0.341255683 0.090745405 0.3107001 0.57567942 0.026144131 0.02102274 1.13E-08 7.945582763 -0.203254652 GMYDGPVFDLTT(ph)TPK ddPTM_HeLa_Curcumin_4h_R1 1 GMYDGPVFDLTTTPK 15 0 Q14195-2;Q14195;H0YBT4 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 1 0 GMYDGPVFDLT(0.002)T(0.608)T(0.39)PK 149.32 0.001306 653240000 7004.3 5932.6 5855.8 6179.9 6489.4 7542.7 7016.8 5088.3 6796.9 5798.9 TRUE FALSE FALSE 6449.902264 6445.387509 6072.821099 6154.329211 6412.018143 5978.258996 7213.672523 6639.699246 6051.297075 6000.411343 1.074910018 1.07415761 1.012067465 1.025651219 1.068596431 0.996308195 1.202196335 1.10654068 1.008480374 1 12.55084569 -4.763618071 24.99999964 1.036771352 1.154368515 0.645545038 0.036005373 25.87941734 296978.202 0.005313822 0.017161481 1.72E-05 4.763618071 0.117597163 GMYDGPVFDLTTT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 GMYDGPVFDLTTTPK 15 0 Q14195-2;Q14195;H0YBT4 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 1 0 GMYDGPVFDLT(0.002)T(0.031)T(0.968)PK 162.67 0.00080297 666810000 7164.3 5943.2 6515.1 6294.4 6202.8 8518.3 7791.4 5699.5 6783.2 6579.5 TRUE FALSE FALSE 6597.238095 6456.903726 6756.555337 6268.355441 6128.835661 6751.508559 8010.005715 7437.251313 6039.099931 6808.137135 0.969022504 0.948409763 0.992423508 0.920715214 0.900222122 0.991682222 1.176534132 1.092406214 0.887041464 1 12.73304438 -4.824831795 6.535894993 0.972135822 1.133915096 0.710018408 0.045366782 0.068490856 5.417605476 0.005452511 0.016854886 1.50E-05 4.824831795 0.161779274 GNAEGS(ph)S(ph)DEEGKLVIDEPAK ddPTM_HeLa_Curcumin_4h_R1 2 GNAEGSSDEEGKLVIDEPAK 20 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 2 0 GNAEGS(1)S(1)DEEGKLVIDEPAK;GNAEGS(1)S(1)DEEGKLVIDEPAK ; 68.525 0.0051956 262850000 14065.9 13732.4 14012.7 13750.7 18735.4 14784.5 15060.6 14005.4 11658.5 12281.9 TRUE FALSE FALSE 12952.56917 14919.36747 14532.02299 13693.80325 18511.99259 11718.02804 15483.1599 18275.58199 10379.59172 12708.69511 1.019189544 1.173949594 1.143470896 1.077514499 1.456639917 0.922048089 1.218312326 1.438037645 0.816731508 1 13.63352829 -1.000000001 0.17165613 0.955230723 2.486090194 0.406228941 0.151135251 46.29742605 0.489089722 0.19696558 18.34844955 0.1 1.000000001 1.530859471 GNAEGS(ph)S(ph)DEEGKLVIDEPAKEK ddPTM_HeLa_Curcumin_4h_R1 1 GNAEGSSDEEGKLVIDEPAKEK 22 2 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 2 0 GNAEGS(1)S(1)DEEGKLVIDEPAKEK 64.377 0.0056761 0 2262.5 2050 2805.1 2344.5 2525.9 2546 2640 2400.4 2478.6 2359.9 TRUE FALSE FALSE 2083.420738 2227.192865 2909.059474 2334.79908 2495.780292 2017.930901 2714.071295 3132.27091 2206.703781 2441.906349 0.853194365 0.912071368 1.191306732 0.956137847 1.022062248 0.826375222 1.111455931 1.282715412 0.903680758 1 11.25379216 S(ph)VSSNVASVSPIPAGSKK ddPTM_HeLa_Curcumin_4h_R1 2 SVSSNVASVSPIPAGSKK 18 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 0 S(0.49)VS(0.41)S(0.1)NVASVSPIPAGSKK;S(0.4)VS(0.328)S(0.269)NVAS(0.003)VSPIPAGSKK ; 81.48 0.0027583 31986000 1504.41 930.05 1699.98 1691.82 1556.85 1856.23 2177.8 13941.5 1354.57 1643.67 TRUE FALSE FALSE 1385.334361 1010.439378 1762.982754 1684.819697 1538.285581 1471.226974 2238.903207 18192.19917 1205.97706 1700.78741 0.814525292 0.594100927 1.036568559 0.990611576 0.904454943 0.865026966 1.316392157 10.69633927 0.709069842 1 10.73198711 -4.260992515 5.178665321 0.904297351 11.13254001 0.997935104 0.133617303 0.0047714 0.427155831 0.018488489 0.173292301 5.48E-05 4.260992515 10.22824266 up GNAEGSS(ph)DEEGKLVIDEPAK ddPTM_HeLa_Curcumin_4h_R1 2 GNAEGSSDEEGKLVIDEPAK 20 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 0 GNAEGS(0.391)S(0.609)DEEGKLVIDEPAK;GNAEGS(0.218)S(0.782)DEEGKLVIDEPAK ; 65.881 0.0037245 68203000 3517.5 3073.7 3854.5 3246.6 4433.9 3520 3180.4 3644 2930.36 2829.41 TRUE FALSE FALSE 3239.086163 3339.376932 3997.351161 3233.166429 4381.028638 2789.912321 3269.633464 4755.038825 2608.906839 2927.731787 1.106346619 1.140602068 1.365340629 1.104324667 1.496390024 0.952926198 1.116780396 1.624137445 0.891101723 1 11.51556768 -1.000000008 0.073478674 0.73477954 2.312786729 0.334563826 0.185271794 208.1822123 1.13563083 4.144669865 33.90374893 0.099999998 1.000000008 1.578007189 GNAEGSS(ph)DEEGKLVIDEPAKEK ddPTM_HeLa_Curcumin_4h_R1 3 GNAEGSSDEEGKLVIDEPAKEK 22 2 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 0 GNAEGS(0.034)S(0.966)DEEGKLVIDEPAKEK;GNAEGS(0.193)S(0.807)DEEGKLVIDEPAKEK;GNAEGS(0.031)S(0.969)DEEGKLVIDEPAKEK ;; 81.665 0.00056117 127599000 8154.4 7229.2 8381.6 7648.4 8414.9 8722.4 8354.9 7822.5 7110.3 6983.1 TRUE FALSE FALSE 7508.970636 7854.059835 8692.229469 7616.752947 8314.557813 6913.275918 8589.316008 10207.54424 6330.317879 7225.762205 1.039194264 1.086952437 1.202949837 1.054110657 1.150682458 0.956753865 1.188707262 1.412659862 0.876076142 1 12.81893406 -4.403289396 2.929271439 1.045692383 1.42681675 0.618840986 0.088465615 0.129954266 1.783469884 0.010449536 0.096729715 3.95E-05 4.403289396 0.381124367 GNAMVEEGHFAAEDVK ddPTM_HeLa_Curcumin_4h_R1 1 GNAMVEEGHFAAEDVK 16 0 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 95.067 0.0026198 0 2176.3 1476 1903 1964 2097.3 2220.8 1934.4 2128.2 2160.1 1770.9 FALSE FALSE TRUE 2004.043559 1603.578863 1973.526854 1955.873488 2072.291067 1760.181046 1988.674058 2777.078383 1923.142434 1832.438643 1.093648383 0.875106443 1.07699478 1.06736097 1.130892472 0.960567522 1.085260926 1.515509615 1.049498951 1 10.83954918 -4.266944504 4.19667573 1.038234162 1.551341364 0.811048046 0.069538417 0.065840259 2.596939972 0.009525145 0.100350089 5.41E-05 4.266944504 0.513107202 GNDPLTSS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 2 GNDPLTSSPGR 11 0 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 0 GNDPLT(0.001)S(0.005)S(0.994)PGR;GNDPLT(0.001)S(0.008)S(0.991)PGR ; 113.95 0.0052588 6858100000 16019 12912.1 14067.8 13936.3 15552.2 17726.3 14747.6 14357.8 15288.8 13306.5 TRUE FALSE FALSE 14751.07925 14028.16439 14589.16504 13878.63528 15366.75017 14049.66556 15161.37796 18735.42712 13611.65689 13768.89988 1.071333176 1.018829718 1.059573762 1.007969801 1.116047782 1.020391294 1.101132123 1.360706177 0.988579843 1 13.74912567 -4.256481083 2.6500128 1.038443071 1.428254666 0.876850217 0.036464002 0.115755988 1.042407385 0.005022077 0.099870571 5.54E-05 4.256481083 0.389811595 GNDS(ph)DGEGESDDPEK ddPTM_HeLa_Curcumin_4h_R1 1 GNDSDGEGESDDPEK 15 0 O75351;K7EKZ3 O75351 VPS4B Vacuolar protein sorting-associated protein 4B 1 0 GNDS(0.665)DGEGES(0.335)DDPEK 176.17 2.10E-15 0 3526.9 3388.2 3710.3 3315.3 4307.4 3574.6 3444.7 2898.2 2517.7 2613.3 TRUE FALSE FALSE 3247.742143 3681.06091 3847.806982 3301.582167 4256.037068 2833.187666 3541.349011 3781.847838 2241.514609 2704.11198 1.201038332 1.361282719 1.422946612 1.220948759 1.573913025 1.047733114 1.309616257 1.398554448 0.828928175 1 11.40093918 -8.123111924 0.792049583 1.02625307 1.330091307 0.525605421 0.146912955 0.3411446 0.464369786 0.044853055 0.030113255 7.53E-09 8.123111924 0.303838238 GNDS(ph)DGEGESDDPEKKK ddPTM_HeLa_Curcumin_4h_R1 1 GNDSDGEGESDDPEKKK 17 2 O75351;K7EKZ3 O75351 VPS4B Vacuolar protein sorting-associated protein 4B 1 0 GNDS(0.583)DGEGES(0.417)DDPEKKK 71.527 0.012911 43918000 2767.3 2320.4 2733.2 2189.9 2812.8 2806.5 2504.6 2253.7 2400.7 2813.4 TRUE FALSE FALSE 2548.265285 2520.965036 2834.494796 2180.838774 2779.259197 2224.400264 2574.872335 2940.842755 2137.349216 2911.165441 0.875341968 0.865964195 0.973663247 0.749129109 0.954689541 0.764092701 0.884481624 1.010194307 0.734190227 1 11.50738111 -9.209442656 0.69133344 1.010844905 0.879243626 0 0.114458485 0.965638236 0.728594512 0.075046286 0.015576347 6.17E-10 9.209442656 -0.131601279 GNDSDGEGES(ph)DDPEK ddPTM_HeLa_Curcumin_4h_R1 1 GNDSDGEGESDDPEK 15 0 O75351;K7EKZ3 O75351 VPS4B Vacuolar protein sorting-associated protein 4B 1 0 GNDS(0.014)DGEGES(0.986)DDPEK 181.97 4.62E-05 12968000 4612.7 3874.1 5402.1 4212 6336.4 5092.3 4945 4138.3 3528.7 3553.3 TRUE FALSE FALSE 4247.599928 4208.959941 5602.306578 4194.57186 6260.842568 4036.099578 5083.743391 5400.04862 3141.610438 3676.776911 1.155250925 1.144741725 1.523700435 1.140828492 1.702807301 1.097727623 1.382662999 1.468690854 0.854446847 1 11.84422593 -7.328812644 0.729000952 1.033618616 1.386913516 0.462377693 0.182485373 0.400431994 0.447857755 0.042993076 0.048951054 4.69E-08 7.328812644 0.3532949 RGGIPAS(ph)PIDPFQSR ddPTM_HeLa_Curcumin_4h_R1 2 RGGIPASPIDPFQSR 15 1 Q96LD4-2;Q96LD4 Q96LD4-2 TRIM47 Tripartite motif-containing protein 47 1 0 RGGIPAS(0.997)PIDPFQS(0.003)R;RGGIPAS(1)PIDPFQSR ; 83.776 0.0059762 31002000 4974.1 4660.3 4791.6 4777.7 3922.6 5894.7 7023.3 11898 6246.8 5124.6 TRUE FALSE FALSE 4580.394736 5063.115566 4969.180911 4757.931143 3875.825557 4672.072773 7220.354896 15525.64543 5561.541669 5302.679469 0.863788725 0.954822104 0.93710754 0.897269234 0.730918318 0.881077727 1.36164272 2.927886839 1.048817245 1 12.37250583 -4.260989398 2.465732374 0.915951052 3.383320563 0.981183436 0.083602712 0.049637503 0.367975105 0.01219189 0.257470333 5.48E-05 4.260989398 2.467369511 up GNDT(ph)PLALESTNTEKETSLEETK ddPTM_HeLa_Curcumin_4h_R1 1 GNDTPLALESTNTEKETSLEETK 23 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 GNDT(0.239)PLALES(0.151)T(0.151)NT(0.211)EKET(0.186)S(0.06)LEET(0.001)K 56.29 0.0092253 10769000 1120 769.67 1174.4 1002.8 908.17 1669.8 1435.9 1634.9 917.73 1216.9 TRUE FALSE FALSE 1031.350818 836.1968452 1217.924297 998.6506793 897.3406659 1323.464657 1476.187489 2133.373484 817.057315 1259.187184 0.819060765 0.66407668 0.967230537 0.793091521 0.712634847 1.051046797 1.172333635 1.694246503 0.648876772 1 10.29827705 -4.259302862 1.473213057 0.878158051 2.019577088 0.803507758 0.132005487 0.379588357 0.731085144 0.018225836 0.63345299 5.50E-05 4.259302862 1.141419038 GNDVAFHFNPR ddPTM_HeLa_Curcumin_4h_R1 2 GNDVAFHFNPR 11 0 G3V3R6;P17931 G3V3R6 LGALS3 Galectin;Galectin-3 0 0 ; ; 96.604 0.0052209 16464200 6235.1 4274.8 5307.9 4892.7 5446.2 8193.3 5973 5498.7 5993.9 5092.5 FALSE FALSE TRUE 5741.585256 4644.294664 5504.615443 4872.455304 5381.257622 6493.917222 6140.586304 7175.228317 5336.384166 5269.463996 1.089595689 0.881359977 1.044625307 0.924658619 1.02121537 1.2323677 1.165315165 1.361661892 1.012699616 1 12.3634405 -5.247362631 5.23217233 1.020483352 1.246898311 0.712420844 0.073666173 0.085286692 7.572679967 0.010818223 0.027026981 5.66E-06 5.247362631 0.226414958 GNFNYIEFTR ddPTM_HeLa_Curcumin_4h_R1 2 GNFNYIEFTR 10 0 J3QRS3;P19105;O14950 J3QRS3 MYL12A;MYL12B Myosin regulatory light chain 12A;Myosin regulatory light chain 12B 0 0 ; ; 143.4 0.010936 71627000 2768.9 1831.96 2303.57 2104.67 2266.4 4635.4 3596.7 3306.6 2421 2387.5 FALSE FALSE TRUE 2549.738643 1990.306459 2388.942331 2095.961433 2239.37466 3673.965788 3697.613722 4314.767118 2155.422357 2470.465447 1.032088365 0.805640274 0.967000908 0.848407508 0.906458604 1.487155302 1.49672756 1.74654016 0.872476221 1 11.27056716 -5.171995942 3.9543499 0.976383207 1.594936431 0.898045526 0.100675628 0.056247889 1.614275349 0.014632101 0.039642751 6.73E-06 5.171995942 0.618553224 GNHECASINR ddPTM_HeLa_Curcumin_4h_R1 3 GNHECASINR 10 0 C9JP48;A0A087WYY5;E7ETD8;E9PMD7;F8VR82;F8VYE8;F8W0W8;P62136-3;P36873;P62140;P62136;P36873-2;P62136-2 C9JP48 PPP1CB;PPP1CC;PPP1CA Serine/threonine-protein phosphatase;Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;Serine/threonine-protein phosphatase PP1-gamma catalytic subunit;Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0 0 ;; ;; 119.53 0.00085592 2476860 1556.43 1329.52 1559.64 1548.41 1514.97 1753.2 1106.45 1355.9 1666.47 1380.07 FALSE FALSE TRUE 1433.236923 1444.437785 1617.44163 1542.00309 1496.904972 1389.566557 1137.494009 1769.307668 1483.66241 1428.02733 1.003648105 1.011491695 1.132640529 1.07981343 1.04823272 0.973067201 0.796549187 1.23898726 1.038959395 1 10.47980787 -4.203429296 22.81824308 1.007271605 1.238992502 0.406145308 0.08325822 22533.27269 8862513.454 0.011155405 28.19835024 6.26E-05 4.203429296 0.231720897 GNIET(ph)TSEDGQVFSPK ddPTM_HeLa_Curcumin_4h_R1 1 GNIETTSEDGQVFSPK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 0 GNIET(0.407)T(0.407)S(0.185)EDGQVFSPK 150.92 0.0010022 29289000 4354.3 3697.4 4021.7 4712.4 3556.2 4839.4 3836.7 4617.1 4379.6 4332.1 TRUE FALSE FALSE 4009.65256 4016.986781 4170.74774 4692.901337 3513.794638 3835.653889 3944.347476 6024.832535 3899.168837 4482.640153 0.894484595 0.896120733 0.930422161 1.046905658 0.783867212 0.855668481 0.879916152 1.344036624 0.869837574 1 12.13013298 -4.257193861 24.79839811 0.929873467 1.344036807 0.756367639 0.07343735 155.7570696 909749.9312 0.010705447 0.111142635 5.53E-05 4.257193861 0.41416334 GNIETTS(ph)EDGQVFSPK ddPTM_HeLa_Curcumin_4h_R1 1 GNIETTSEDGQVFSPK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 0 GNIET(0.071)T(0.223)S(0.707)EDGQVFSPK 117.13 0.0011165 13464000 4680.4 3727.7 3882.6 4260.1 4136 4557.5 4547.9 4889.7 5200.5 4051.9 TRUE FALSE FALSE 4309.941401 4049.905778 4026.492571 4242.472835 4086.680901 3612.223126 4675.501834 6380.547021 4630.018161 4192.703223 1.027962432 0.965941437 0.960357163 1.011870531 0.974712658 0.86154992 1.115152107 1.521821765 1.104303814 1 12.033665 -4.304687455 3.302137318 0.995115715 1.569829518 0.878732959 0.059337056 0.056372943 1.00799096 0.006889087 0.076877786 4.96E-05 4.304687455 0.574713803 GNIETTSEDGQVFS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 GNIETTSEDGQVFSPK 16 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 0 GNIETTSEDGQVFS(1)PK;GNIETTS(0.001)EDGQVFS(0.999)PK;GNIETTS(0.001)EDGQVFS(0.999)PK ;; 181.94 9.06E-17 0 5754.8 5920.15 5481.1 6153.2 5408.36 6292.2 5597 4307.3 6140.9 5580.04 TRUE FALSE FALSE 5299.301508 6431.861386 5684.234388 6127.739689 5343.868839 4987.126792 5754.036756 5620.575942 5467.258634 5773.945975 0.917795478 1.113945543 0.98446269 1.061274164 0.925514174 0.863729383 0.996551887 0.97343757 0.946884273 1 12.49534189 GNIWS(ph)AEK ddPTM_HeLa_Curcumin_4h_R1 1 GNIWSAEK 8 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 0 GNIWS(1)AEK 91.549 0.019999 58469000 5797.9 5693.3 5489.3 5814.6 7477.5 9886.5 9701.6 2890.3 5252.1 3578.3 TRUE FALSE FALSE 5338.990097 6185.403483 5692.738287 5790.540726 7388.335696 7835.928456 9973.800785 3771.539165 4675.95777 3702.645659 1.441939248 1.670536166 1.537478552 1.563892757 1.995420674 2.116305253 2.693695726 1.018606562 1.262869365 1 11.85434078 -7.293943056 0.389748511 0.998322546 2.050702048 0.320647681 0.408546362 0.719367309 0.301829765 0.234223421 0.264194832 5.08E-08 7.293943056 1.052379501 GNIWS(ph)AEKGGNSK ddPTM_HeLa_Curcumin_4h_R1 1 GNIWSAEKGGNSK 13 1 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 0 GNIWS(1)AEKGGNSK 105.53 0.0021886 69607000 2789.3 2183.8 2069.8 2560.3 1867.2 5322.9 3767.1 1138.9 3574.7 2305.7 TRUE FALSE FALSE 2568.523962 2372.557941 2146.508609 2549.706157 1844.93486 4218.870539 3872.794687 1486.145367 3182.564353 2385.822903 1.076577795 0.994440089 0.899693186 1.068690452 0.773290782 1.76830834 1.62325321 0.622906824 1.333948278 1 11.22027124 -5.278840428 24.92271873 1.010568614 1.366665909 0.177915089 0.310097913 773.4716402 1107806.757 0.038831049 0.087018228 5.26E-06 5.278840428 0.356097295 GNIWSAEK(ac)GGNSK ddPTM_HeLa_Curcumin_4h_R1 2 GNIWSAEKGGNSK 13 1 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 0 1 ; GNIWSAEK(1)GGNSK;GNIWSAEK(1)GGNSK 197.38 1.26E-13 9715600 5493.3 4864.5 5192.9 5193.3 4507.7 6887.4 6523.6 6323.4 5732.6 4756.3 FALSE TRUE FALSE 5058.499508 5284.965704 5385.353442 5171.811501 4453.948622 5458.875603 6706.634659 8251.375551 5103.748122 4921.581071 1.027820011 1.073834938 1.094232395 1.050843505 0.904983288 1.109171123 1.362699214 1.676570076 1.037013929 1 12.26490614 -4.51130555 1.868023284 1.020167944 1.729294845 0.942578267 0.05086123 0.081864327 0.417732825 0.007559016 0.084597739 3.08E-05 4.51130555 0.709126901 GNKHDDGTQS(ph)DSENAGAHR ddPTM_HeLa_Curcumin_4h_R1 3 GNKHDDGTQSDSENAGAHR 19 1 H0Y2V6;Q5SW79;Q5SW79-3;Q5SW79-2 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 0 GNKHDDGT(0.001)QS(0.996)DS(0.003)ENAGAHR;GNKHDDGT(0.001)QS(0.985)DS(0.014)ENAGAHR;GNKHDDGT(0.031)QS(0.963)DS(0.005)ENAGAHR ;; 95.624 0.00052909 21573300 4397.2 4316.2 5395.8 4352.3 5906.3 6515.8 3858.42 2034.37 4232.3 4895.7 TRUE FALSE FALSE 4049.15698 4689.273095 5595.773095 4334.291336 5835.87123 5164.349632 3966.676881 2654.640048 3768.027279 5065.825211 0.799308466 0.925668159 1.104612351 0.855594332 1.152008012 1.019448839 0.783026795 0.524029144 0.743813125 1 12.30658158 -4.400106339 2.998473302 0.938834816 0.510208354 0.533159703 0.12241319 0.182432526 2.629489905 0.016974011 0.154443556 3.98E-05 4.400106339 -0.428626462 GNKS(ph)PS(ph)PPDGS(ph)PAATPEIR ddPTM_HeLa_Curcumin_4h_R1 1 GNKSPSPPDGSPAATPEIR 19 1 O00499-6;O00499-2;O00499;O00499-9;O00499-7;O00499-4;O00499-11;O00499-3;O00499-5;O00499-10;O00499-8 O00499-6 BIN1 Myc box-dependent-interacting protein 1 3 0 GNKS(1)PS(1)PPDGS(0.985)PAAT(0.015)PEIR 57.648 0.01774 6986200 4997.7 4869.2 4573 4010.8 3774.9 3346.4 2520.1 2689.8 5199.6 4965.9 TRUE FALSE FALSE 4602.126771 5290.071951 4742.479403 3994.204372 3729.886783 2652.318918 2590.807223 3509.907638 4629.216889 5138.464655 0.89562293 1.029504396 0.922937048 0.777314751 0.72587573 0.516169536 0.504198705 0.683065443 0.900894956 1 12.32712164 -5.831924275 1.46392871 0.956115027 0.563266786 0.863216091 0.065604461 0.099244094 0.427549792 0.010639109 0.025252427 1.47E-06 5.831924275 -0.392848241 GNKS(ph)PSPPDGS(ph)PAATPEIR ddPTM_HeLa_Curcumin_4h_R1 5 GNKSPSPPDGSPAATPEIR 19 1 O00499-6;O00499-2;O00499;O00499-9;O00499-7;O00499-4;O00499-11;O00499-3;O00499-5;O00499-10;O00499-8 O00499-6 BIN1 Myc box-dependent-interacting protein 1 2 0 GNKS(0.997)PS(0.034)PPDGS(0.951)PAAT(0.018)PEIR;GNKS(0.513)PS(0.487)PPDGS(0.985)PAAT(0.015)PEIR;GNKS(0.747)PS(0.339)PPDGS(0.91)PAAT(0.004)PEIR;GNKS(0.998)PS(0.003)PPDGS(0.997)PAAT(0.003)PEIR;GNKS(0.941)PS(0.061)PPDGS(0.575)PAAT(0.423)PEIR ;;;; 114.71 0.00023272 340545000 19382.8 16411.1 17343.7 18203.9 17400.8 20697.7 15358 13205.2 21157.6 18820.7 TRUE FALSE FALSE 17848.63093 17829.60236 17986.47278 18128.57709 17193.30682 16404.76371 15788.90415 17231.40469 18836.66421 19474.71792 0.916502668 0.915525577 0.923580657 0.930877518 0.882852676 0.84236207 0.810738528 0.884808949 0.967236819 1 14.24931481 -1 0.029794685 1.486913002 0.050818803 0.736849136 0.027048995 390.8573278 0.902298792 14.00669173 33.44024153 0.1 1 -1.436094199 GNKS(ph)PSPPDGSPAATPEIR ddPTM_HeLa_Curcumin_4h_R1 1 GNKSPSPPDGSPAATPEIR 19 1 O00499-6;O00499-2;O00499;O00499-9;O00499-7;O00499-4;O00499-11;O00499-3;O00499-5;O00499-10;O00499-8 O00499-6 BIN1 Myc box-dependent-interacting protein 1 1 0 GNKS(0.722)PS(0.277)PPDGSPAATPEIR 74.308 0.0032923 34711000 2274.2 1530.6 1837.3 2474.2 2268.1 614.78 969.39 1611 2371.4 1735.5 TRUE FALSE FALSE 2094.19467 1662.898244 1905.391954 2463.962416 2241.054389 487.267698 996.5884744 2102.186484 2111.263353 1795.808496 1.166157012 0.925988627 1.061021795 1.372063013 1.247936177 0.271336114 0.554952533 1.170607272 1.175661747 1 10.81041779 -5.281831073 24.99733214 1.099440936 0.654563966 0.442977183 0.238991922 549.6090399 673742.1495 0.03344476 0.074867742 5.23E-06 5.281831073 -0.444876971 GNKSPS(ph)PPDGSPAATPEIR ddPTM_HeLa_Curcumin_4h_R1 2 GNKSPSPPDGSPAATPEIR 19 1 O00499-6;O00499-2;O00499;O00499-9;O00499-7;O00499-4;O00499-11;O00499-3;O00499-5;O00499-10;O00499-8 O00499-6 BIN1 Myc box-dependent-interacting protein 1 1 0 GNKS(0.11)PS(0.89)PPDGS(0.001)PAATPEIR;GNKS(0.378)PS(0.583)PPDGS(0.039)PAAT(0.001)PEIR ; 186.17 8.50E-07 25104200 3102.9 2383.79 2722.34 2621.54 2876.73 3007.1 2287.18 2271.5 3116.4 2645.22 TRUE FALSE FALSE 2857.302191 2589.834186 2823.232315 2610.692762 2842.426874 2383.393563 2351.352115 2964.069893 2774.538717 2737.141198 1.043900181 0.946182165 1.031452932 0.953802735 1.038465562 0.87076018 0.859054007 1.082907194 1.013662985 1 11.41845414 -5.276155092 24.72431488 1.012141371 0.929721811 0.170038228 0.064741364 657.5105312 1104702.797 0.008695597 0.019523526 5.29E-06 5.276155092 -0.082419561 GNPTVEVDLFTS(ph)K ddPTM_HeLa_Curcumin_4h_R1 2 GNPTVEVDLFTSK 13 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798 P06733 ENO1 Alpha-enolase;Enolase 1 0 GNPTVEVDLFT(0.077)S(0.923)K;GNPTVEVDLFT(0.068)S(0.932)K ; 206.66 4.67E-09 26344500 5851.8 5175.6 5623.1 6599.5 6478.2 7575.9 5829.8 5494.7 6802.8 5683.4 TRUE FALSE FALSE 5388.623855 5622.955802 5831.497033 6572.193018 6400.951696 6004.572942 5993.368498 7170.008736 6056.54986 5880.897727 0.916292734 0.956139022 0.991599804 1.11754928 1.088431051 1.021029989 1.019124762 1.219203099 1.029868252 1 12.52182069 -6.412783004 4.274662636 0.959516861 1.084323541 0.463780835 0.060155011 0.145924259 4.495052003 0.009144166 0.014095764 3.87E-07 6.412783004 0.12480668 GNPTVEVDLFTSK ddPTM_HeLa_Curcumin_4h_R1 1 GNPTVEVDLFTSK 13 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8YEG5;A0A2R8Y798 P06733 ENO1 Alpha-enolase;Enolase 0 0 205.8 1.06E-19 1416800 489.93 385.33 517.06 430.02 556.27 600.3 454.3 491.7 311.45 396.63 FALSE FALSE TRUE 451.1515235 418.6362082 536.2226985 428.2406912 549.6368436 475.7910132 467.0464353 641.6170665 277.2847142 410.412863 1.099262631 1.020036763 1.306544572 1.043438766 1.339229086 1.159298492 1.137991709 1.563345412 0.675623839 1 8.680932138 -1 0.224948379 1.010687299 3.163828271 0.476758673 0.162930156 28.33921804 0.341929688 0.077606783 22.53089281 0.1 1 2.153140972 GNRGS(ph)GGGGGGGGQGSTNYGK ddPTM_HeLa_Curcumin_4h_R1 2 GNRGSGGGGGGGGQGSTNYGK 21 1 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 0 GNRGS(1)GGGGGGGGQGSTNYGK;GNRGS(1)GGGGGGGGQGSTNYGK ; 146.6 0.00020082 9258800 1960.33 1443.67 1684.37 1430.98 1599.45 2568.21 2353.85 1309.37 2062.87 1476.28 TRUE FALSE FALSE 1805.167812 1568.454402 1746.794234 1425.058984 1580.377603 2035.534296 2419.892696 1708.590885 1836.578322 1527.58062 1.181716885 1.026757201 1.143503793 0.932886268 1.034562486 1.332521681 1.584134195 1.118494738 1.202279145 1 10.57703281 -5.212643228 5.788516534 1.072823326 1.373047467 0.468518277 0.131304028 0.123857083 10.04963701 0.017489913 0.044965727 6.13E-06 5.212643228 0.300224141 GNS(ph)PPSSGEACR ddPTM_HeLa_Curcumin_4h_R1 2 GNSPPSSGEACR 12 0 P41227;P41227-2 P41227 NAA10 N-alpha-acetyltransferase 10 1 0 GNS(0.996)PPS(0.002)S(0.002)GEACR;GNS(0.624)PPS(0.188)S(0.188)GEACR ; 113.37 0.0045779 43313200 5050.4 6032.7 7290.9 6571.3 5807.1 6335.5 4483 4675.2 6120.6 6821.6 TRUE FALSE FALSE 4650.655511 6554.139707 7561.107168 6544.109702 5737.854125 5021.445884 4608.780915 6100.646958 5449.185493 7058.650092 0.658859052 0.928525939 1.071183168 0.927104987 0.81288264 0.711388979 0.652926672 0.864279555 0.771986913 1 12.78517659 -5.470926091 4.643146614 0.867688309 0.735814305 0.22589682 0.119595457 0.352037338 16.18034578 0.022481688 0.050554263 3.38E-06 5.470926091 -0.131874004 GNS(ph)PPSSGEACREEK ddPTM_HeLa_Curcumin_4h_R1 2 GNSPPSSGEACREEK 15 1 P41227;P41227-2 P41227 NAA10 N-alpha-acetyltransferase 10 1 0 GNS(0.541)PPS(0.362)S(0.098)GEACREEK;GNS(0.999)PPS(0.001)SGEACREEK ; 118.15 0.00063932 84371000 7725 6322.7 6768.7 7668.2 6179.9 8627.3 6172.3 7373.6 9103.1 7308.5 TRUE FALSE FALSE 7113.558099 6869.206015 7019.553976 7636.47102 6106.208729 6837.90073 6345.478126 9621.776696 8104.512705 7562.469831 0.940639534 0.908328386 0.928209187 1.00978532 0.80743578 0.904188828 0.839074835 1.272306126 1.071675377 1 12.88464177 -9.035205814 0.900368597 0.998849774 0.941408524 0.047219451 0.122883639 1.861431045 2.816425523 0.066327331 0.02183493 9.22E-10 9.035205814 -0.05744125 GNS(ph)RPGTPSAEGGSTSSTLR ddPTM_HeLa_Curcumin_4h_R1 1 GNSRPGTPSAEGGSTSSTLR 20 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 0 GNS(0.989)RPGT(0.011)PSAEGGSTSSTLR 65.374 0.0040436 27414000 372.03 199.68 302.12 375.43 341.17 292.99 254.34 429.62 189.42 195.94 TRUE FALSE FALSE 342.5834329 216.9394494 313.316833 373.8765701 337.1017706 232.2205713 261.4760959 560.6091603 168.6410999 202.7489004 1.689693173 1.069990757 1.545344179 1.844037474 1.662656468 1.145360448 1.289654816 2.76504168 0.831773191 1 7.66355028 -11.37655736 0.153467465 3.36E-45 1.865314854 0.327503225 0.436421712 39.41939484 0.770261115 15.02369857 1.162593253 4.20E-12 11.37655736 1.865314854 GNSPPS(ph)SGEACREEK ddPTM_HeLa_Curcumin_4h_R1 1 GNSPPSSGEACREEK 15 1 P41227;P41227-2 P41227 NAA10 N-alpha-acetyltransferase 10 1 0 GNS(0.145)PPS(0.809)S(0.046)GEACREEK 73.415 0.010707 293410000 4608.1 3479 4238.5 4124 3907.9 4831.6 3143.6 4377.8 4724.2 4179.1 TRUE FALSE FALSE 4243.364023 3779.709258 4395.582539 4106.935981 3861.300845 3829.471697 3231.800955 5712.571067 4205.967079 4324.323414 0.981278137 0.87405795 1.016478676 0.949729145 0.892926008 0.885565516 0.747354128 1.321032337 0.972630092 1 12.07825871 -7.494972204 20.10721067 0.991740693 0.943172161 0.003700382 0.14056787 113.0896815 81488.80841 0.022348158 0.024321026 3.20E-08 7.494972204 -0.048568532 GNSRPGT(ph)PSAEGGSTSSTLR ddPTM_HeLa_Curcumin_4h_R1 2 GNSRPGTPSAEGGSTSSTLR 20 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 0 GNS(0.012)RPGT(0.726)PS(0.259)AEGGS(0.001)TSSTLR;GNSRPGT(0.999)PS(0.001)AEGGSTSSTLR ; 163.04 5.82E-05 140903000 4250.7 3513.4 3830.5 4183.4 3862.6 4420.9 3079.7 2875.2 3644.4 3212.5 TRUE FALSE FALSE 3914.25261 3817.082641 3972.4617 4166.090199 3816.541018 3503.955506 3166.108093 3751.835244 3244.618438 3324.134136 1.17752547 1.148293807 1.195036523 1.253285827 1.14813087 1.054095702 0.952460991 1.128665418 0.976079275 1 11.69876288 -3.929930587 20.92362695 1.102086114 1.906198288 0.007412369 0.096144451 3073.123379 1428211.129 0.01426085 64045.16629 0.000117509 3.929930587 0.804112174 GNVFS(ph)SPT(ph)AAGTPNKETAGLK ddPTM_HeLa_Curcumin_4h_R1 1 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 2 0 GNVFS(0.706)S(0.295)PT(0.646)AAGT(0.339)PNKET(0.014)AGLK 88.244 0.00096859 14724000 3561.1 2924 2884.2 3356.1 3009.9 5756.4 5798.2 2324 3695.5 2368 TRUE FALSE FALSE 3279.235177 3176.737531 2991.090989 3342.213347 2974.008908 4562.457752 5960.881887 3032.576902 3290.112896 2450.287824 1.338306115 1.296475255 1.220710057 1.364008471 1.213738598 1.862008907 2.432727221 1.237641094 1.342745478 1 11.25873551 -5.25467593 5.624915225 1.19636548 1.908474262 0.452791504 0.290553598 0.090355979 11.01481585 0.039350472 0.096806044 5.56E-06 5.25467593 0.712108781 GNVFSS(ph)PT(ph)AAGTPNKETAGLK ddPTM_HeLa_Curcumin_4h_R1 1 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 2 0 GNVFS(0.19)S(0.73)PT(0.716)AAGT(0.239)PNKET(0.125)AGLK 74.408 0.0034393 507390000 6169.6 4878.7 5665.2 6059.4 5760.2 10080 10826 3847.3 5972.7 3986.5 TRUE FALSE FALSE 5681.26965 5300.393089 5875.157296 6034.327808 5691.513377 7989.294375 11129.74842 5020.324059 5317.509753 4125.030578 1.377267281 1.284934254 1.424269999 1.462856503 1.379750591 1.936784279 2.698100829 1.217039235 1.289083718 1 12.0101891 -5.750344904 0.35052939 1.070252922 2.203820265 0.319205094 0.376592266 1.816193682 0.333245516 0.158510947 0.786170871 1.78E-06 5.750344904 1.133567343 GNVFSS(ph)PTAAGT(ph)PNK ddPTM_HeLa_Curcumin_4h_R1 1 GNVFSSPTAAGTPNK 15 0 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 2 0 GNVFS(0.065)S(0.593)PT(0.348)AAGT(0.995)PNK 116 0.0073142 11705000 1713.3 1636.6 1612.7 1740.2 1993.9 2987.9 2846 1458.2 1824.3 1221.9 TRUE FALSE FALSE 1577.690497 1778.060411 1672.468081 1732.999513 1970.124045 2368.175859 2925.8511 1902.798467 1624.178854 1264.360934 1.247816549 1.406291798 1.322777409 1.37065253 1.558197499 1.873022011 2.31409483 1.504948797 1.284584813 1 10.30419265 -5.803072954 0.425030707 1.055624495 2.11061223 0.582701883 0.225711297 0.721880912 0.20132745 0.067004211 0.322326834 1.57E-06 5.803072954 1.054987735 GNVFSS(ph)PTAAGTPNK ddPTM_HeLa_Curcumin_4h_R1 3 GNVFSSPTAAGTPNK 15 0 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 1 0 GNVFS(0.075)S(0.887)PT(0.038)AAGTPNK;GNVFS(0.028)S(0.936)PT(0.035)AAGTPNK;GNVFS(0.028)S(0.87)PT(0.102)AAGTPNK ;; 191.63 2.36E-06 44344000 9537.3 8465.8 8769.3 8516 10005.9 13328.7 11012.3 6039.6 8156.4 6134.7 TRUE FALSE FALSE 8782.412641 9197.546029 9094.297972 8480.763048 9886.586178 10564.17737 11321.2755 7881.046237 7261.663326 6347.880368 1.383518928 1.448916094 1.432651128 1.335999193 1.557462587 1.664205492 1.783473355 1.241524065 1.143950879 1 12.63205922 -9.139069784 0.267239965 0.748724351 1.602634212 0.556991891 0.148851898 1.989484624 0.211917453 0.562272064 0.114874685 7.26E-10 9.139069784 0.853909861 GNVFSS(ph)PTAAGTPNKETAGLK ddPTM_HeLa_Curcumin_4h_R1 1 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 1 0 GNVFS(0.284)S(0.602)PT(0.114)AAGTPNKETAGLK 70.679 0.0013371 148590000 2247.1 1567 1782.7 2174.5 1816.5 3105.6 2409.9 1464.5 2675 1654.3 TRUE FALSE FALSE 2069.239664 1702.444498 1848.76843 2165.502495 1794.839424 2461.463553 2477.515308 1911.019308 2381.559193 1711.786802 1.208818564 0.994542367 1.080022599 1.265053856 1.048518088 1.437949837 1.44732703 1.116388622 1.391270916 1 10.74128731 -5.26720406 24.94063843 1.101206992 1.345232352 0.232881322 0.147918069 304.7811655 1318624.692 0.017605565 0.040407576 5.41E-06 5.26720406 0.24402536 GNVFSSPT(ph)AAGTPNKETAGLK ddPTM_HeLa_Curcumin_4h_R1 1 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 1 0 GNVFS(0.159)S(0.255)PT(0.585)AAGTPNKETAGLK 117.27 1.05E-05 143990000 2649.9 2099 2264.6 2241.1 1584.4 3644.4 2620 1871.9 2761.5 1887.2 TRUE FALSE FALSE 2440.157619 2280.428207 2348.528068 2231.826922 1565.507065 2888.510359 2693.510149 2442.633693 2458.570359 1952.78006 1.249581389 1.167785484 1.202658772 1.142897231 0.801681202 1.479178541 1.379320797 1.250849363 1.259010377 1 10.93131375 -13.52287875 0.203509996 1.20E-11 1.254529952 0 0.183276125 67.63899043 0.828026416 27.0848671 0.169588086 3.00E-14 13.52287875 1.254529952 GNVFSSPTAAGT(ph)PNKET(ph)AGLK ddPTM_HeLa_Curcumin_4h_R1 1 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 2 0 GNVFS(0.106)S(0.376)PT(0.331)AAGT(0.572)PNKET(0.615)AGLK 69.256 0.0020833 490950000 6274.2 4380 4606.9 4932.2 4557.2 8333.6 8438.7 3475 5432.6 3455.9 TRUE FALSE FALSE 5777.590449 4758.587683 4777.635767 4911.791863 4502.858366 6605.117421 8675.46721 4534.511503 4836.657372 3575.992268 1.615660778 1.330704131 1.336030788 1.373546556 1.259191304 1.847072624 2.426030752 1.268042871 1.352535747 1 11.8041279 -10.36806438 0.095057453 1.78E-13 2.197178882 0.213763145 0.336804877 52.51141959 0.848568446 17.52396152 4.998321134 4.28E-11 10.36806438 2.197178882 GNVFSSPTAAGTPNKETAGLK ddPTM_HeLa_Curcumin_4h_R1 2 GNVFSSPTAAGTPNKETAGLK 21 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 0 0 ; ; 243.61 5.81E-50 6309900 2205.2 2196.4 2063 2293.6 2115.7 2625 2270.63 1939.84 2643.6 1849.91 FALSE FALSE TRUE 2030.656093 2386.247029 2139.456595 2284.109691 2090.471659 2080.54541 2334.337767 2531.288286 2353.603694 1914.194235 1.060841192 1.246606528 1.117679991 1.193248652 1.092089623 1.086904021 1.219488453 1.32237797 1.229553225 1 10.90252151 -1 0.08751714 0.859974961 1.928884423 0 0.100193629 85.34128786 0.543415009 0.923139453 11.01912806 0.1 1 1.068909462 GNVGVVLFNFGK ddPTM_HeLa_Curcumin_4h_R1 1 GNVGVVLFNFGK 12 0 P33316;A0A0C4DGL3;H0YKC5;H0YKI0;H0YMP1;H0YNW5;H0YMM5;P33316-2;H0YNJ9 P33316;H0YNW5;P33316-2 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 0 0 182.65 1.56E-09 382480 0 0 0 0 147.31 386.57 317.4 347.74 46.414 100.28 FALSE FALSE TRUE 0 0 0 0 145.5534245 306.3910245 326.3053898 453.7643252 41.32250032 103.7647225 0 0 0 0 1.402725521 2.952747494 3.14466595 4.373011502 0.398232649 1 6.697172236 -5.225718353 1.691250706 0.392572156 3.841534367 0.924301717 0.419468875 0.094607914 0.508436133 0.07988363 0.286428083 5.95E-06 5.225718353 3.44896221 GNVVPS(ph)PLPTRR ddPTM_HeLa_Curcumin_4h_R1 2 GNVVPSPLPTRR 12 1 H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9;Q9Y2V2 H3BTK3 CARHSP1 Calcium-regulated heat stable protein 1 1 0 GNVVPS(0.631)PLPT(0.369)RR;GNVVPS(0.999)PLPT(0.001)RR ; 111.66 0.0080108 148840000 7768.1 7198.4 7359.6 7454.9 7551.4 9336.8 7726.7 4185.82 7956.6 6836.4 TRUE FALSE FALSE 7153.246688 7820.597621 7632.35325 7424.053599 7461.354487 7400.242433 7943.490407 5462.057249 7083.780886 7073.964391 1.011207619 1.105546648 1.078935775 1.049489818 1.0547628 1.046123789 1.122919196 0.772135248 1.001387694 1 12.78830324 -4.24861534 24.80942808 1.031832167 0.772135063 0.775506916 0.043996376 795.1985134 1538364.223 0.006915776 0.167886448 5.64E-05 4.24861534 -0.259697103 GPAADPS(ph)SPGTSGVGPAAGAGDSR ddPTM_HeLa_Curcumin_4h_R1 2 GPAADPSSPGTSGVGPAAGAGDSR 24 0 A0A0U1RRM4 A0A0U1RRM4 1 0 GPAADPS(0.61)S(0.384)PGT(0.005)S(0.001)GVGPAAGAGDSR;GPAADPS(0.869)S(0.117)PGT(0.011)S(0.003)GVGPAAGAGDSR ; 281.16 1.77E-74 57405000 5686.9 4806.9 4587.9 4760.3 4998.7 5977.2 5197.3 5880.5 5601.5 4594.8 TRUE FALSE FALSE 5236.775864 5222.387017 4757.93161 4740.60314 4939.093767 4737.461343 5343.12225 7673.43738 4987.029464 4754.468958 1.101442855 1.098416472 1.000728294 0.997083624 1.038831847 0.996422815 1.123810524 1.613942051 1.048914087 1 12.2150685 -4.265986649 3.352885357 1.042213258 1.686872191 0.953293143 0.03818597 0.056269691 1.041569835 0.006678956 0.092342681 5.42E-05 4.265986649 0.644658934 GPAADPSS(ph)PGTSGVGPAAGAGDSR ddPTM_HeLa_Curcumin_4h_R1 2 GPAADPSSPGTSGVGPAAGAGDSR 24 0 A0A0U1RRM4 A0A0U1RRM4 1 0 GPAADPS(0.012)S(0.976)PGT(0.009)S(0.003)GVGPAAGAGDSR;GPAADPS(0.104)S(0.88)PGT(0.013)S(0.004)GVGPAAGAGDSR ; 236.66 1.47E-31 69136000 5475.3 4742.2 4263.6 4262.7 4427.8 5772.9 5319.2 5957.8 5225.6 4566 TRUE FALSE FALSE 5041.924227 5152.094637 4421.612767 4245.062077 4375.001377 4575.535466 5468.442436 7774.305794 4652.364754 4724.66816 1.067148857 1.090466984 0.935856788 0.898488938 0.92599125 0.968435308 1.157423601 1.645471286 0.984696617 1 12.20599729 -4.284344599 2.676520947 1.009571282 1.753375998 0.911633127 0.06162873 0.104383156 1.014579906 0.010075581 0.167802425 5.20E-05 4.284344599 0.743804716 VDINT(ph)PDVDVHGPDWHLK ddPTM_HeLa_Curcumin_4h_R1 2 VDINTPDVDVHGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VDINT(1)PDVDVHGPDWHLK;VDINT(1)PDVDVHGPDWHLK ; 83.245 0.003021 684920000 12605.7 10187.3 12455.7 13737.3 11323.6 13189.5 12039.8 24197.9 11280.1 9236.9 TRUE FALSE FALSE 11607.94554 11067.84482 12917.3192 13680.45869 11188.57347 10453.84902 12377.60438 31575.72832 10042.70125 9557.881587 1.214489365 1.157980952 1.351483494 1.431327493 1.17061227 1.093741215 1.295015456 3.303632508 1.050724594 1 13.22247518 -4.26094694 4.477869984 1.154158122 3.449560434 0.962023244 0.125677683 0.030089091 1.506535746 0.020740822 0.217442357 5.48E-05 4.26094694 2.295402312 up DADS(ph)QNPDAPEGK ddPTM_HeLa_Curcumin_4h_R1 2 DADSQNPDAPEGK 13 0 A0A3B3ISK1;A0A3B3ITV3;A0A3B3ISC6;A0A3B3IT15;A0A3B3IS84;P53621;P53621-2;A0A3B3IU89 A0A3B3ISK1 COPA Coatomer subunit alpha;Xenin;Proxenin 1 0 DADS(1)QNPDAPEGK;DADS(1)QNPDAPEGK ; 210.08 2.13E-09 16570700 1391.45 1022.02 1320.91 1604.79 1424.15 2158.03 2883.5 33427 500.64 1191.93 TRUE FALSE FALSE 1281.315264 1110.358855 1369.864087 1598.149804 1407.167941 1710.430252 2964.403249 43618.73842 445.7210445 1233.349479 1.038890668 0.900279178 1.110686071 1.295780176 1.140932044 1.386817185 2.403538738 35.36608169 0.361390711 1 10.26836594 -4.26089253 5.300564381 1.088138787 36.78730746 0.9993225 0.267230584 0.002360376 0.233170035 0.033015198 0.305327927 5.48E-05 4.26089253 35.69916867 up GPAGEAGAS(ph)PPVR ddPTM_HeLa_Curcumin_4h_R1 1 GPAGEAGASPPVR 13 0 Q13425;A0A140TA73;Q13425-2 Q13425 SNTB2 Beta-2-syntrophin 1 0 GPAGEAGAS(1)PPVR 103.11 0.0055243 47371000 2653.5 5366.1 3338.5 4995.2 1868.9 1887.2 2250.4 1918.1 5322.7 6240.1 TRUE FALSE FALSE 2443.472675 5829.921773 3462.227747 4974.531186 1846.614588 1495.773447 2313.540167 2502.91986 4738.813127 6456.943011 0.378425622 0.902891936 0.536202308 0.770415842 0.285988987 0.2316535 0.358302708 0.387632329 0.733909703 1 12.65663558 -13.52287875 0.1933179 3.390469509 0.34956384 0.391829361 0.20223536 32.82286983 0.391689787 29.77814172 0.230572208 3.00E-14 13.52287875 -3.040905669 GPAPAPQQCS(ph)EPETK ddPTM_HeLa_Curcumin_4h_R1 2 GPAPAPQQCSEPETK 15 0 Q3YEC7-2;Q3YEC7;G3V154 Q3YEC7-2 RABL6 Rab-like protein 6 1 0 GPAPAPQQCS(0.909)EPET(0.091)K;GPAPAPQQCS(0.918)EPET(0.082)K ; 182.57 4.23E-05 31738000 6516.2 5625.3 5899 6092.5 6215.6 7186.4 4953.3 2515.6 6451.4 4904.1 TRUE FALSE FALSE 6000.435894 6111.525866 6117.622129 6067.290849 6141.48303 5695.859633 5092.276267 3282.59486 5743.697561 5074.51711 1.182464413 1.204356145 1.205557494 1.195639056 1.210259596 1.122443675 1.003499674 0.646878272 1.131870764 1 12.30905483 -4.271863741 2.329971016 1.12338915 0.537437326 0.836176668 0.067162631 0.244802743 1.58444753 0.013517061 0.287545364 5.35E-05 4.271863741 -0.585951824 GPAS(ph)DSETEDAS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 GPASDSETEDASR 13 0 Q96ST2-3;Q96ST2 Q96ST2-3 IWS1 Protein IWS1 homolog 2 0 GPAS(1)DSETEDAS(1)R 168.93 0.00045549 3170900 3343.2 3133.4 3594.9 3643.4 4164.7 3998.8 3299.6 3212.1 3103.3 3108.5 TRUE FALSE FALSE 3078.582192 3404.237134 3728.130156 3628.324576 4115.038673 3169.403804 3392.177896 4191.454503 2762.875754 3216.520144 0.957115782 1.058360272 1.15905699 1.128027935 1.27934491 0.985351766 1.054611115 1.303102209 0.858964232 1 11.65128501 -6.984032204 3.302844485 0.980056035 1.144148421 0.478116979 0.096509949 0.170281202 3.894512162 0.014340331 0.018660884 1.04E-07 6.984032204 0.164092386 GPAS(ph)TPTYS(ph)PAPTQPAPR ddPTM_HeLa_Curcumin_4h_R1 1 GPASTPTYSPAPTQPAPR 18 0 Q6P1N0;Q6P1N0-2;K7EJY5 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 2 0 GPAS(0.678)T(0.321)PT(0.028)Y(0.004)S(0.969)PAPTQPAPR 172.42 1.63E-05 12594000 1378.8 1345.2 1168.8 1056.3 1326.8 3096.2 3182.4 1076.1 1530 1041.7 TRUE FALSE FALSE 1269.666525 1461.473094 1212.116756 1051.92931 1310.978777 2454.013219 3271.689579 1404.197936 1362.162828 1077.898997 1.177908624 1.355853468 1.124517936 0.975907124 1.216235268 2.276663421 3.035246889 1.302717545 1.263720285 1 10.07400628 -5.278559188 5.249753667 1.106446921 2.294809979 0.577231747 0.407004465 0.075609786 6.689234032 0.051792551 0.123769224 5.27E-06 5.278559188 1.188363057 GPASQFYITPS(ph)TSLSPR ddPTM_HeLa_Curcumin_4h_R1 1 GPASQFYITPSTSLSPR 17 0 H0YIQ2;P49750-3;P49750-1;P49750 H0YIQ2 YLPM1 YLP motif-containing protein 1 1 0 GPASQFYIT(0.01)PS(0.597)T(0.143)S(0.25)LSPR 154.48 0.00018328 53869000 1818.1 1695.7 1671 1626.4 1593.8 2361.8 1859.1 1556.7 1966.9 1626.6 TRUE FALSE FALSE 1674.195467 1842.268752 1732.92873 1619.670388 1574.794976 1871.936057 1911.261342 2031.330664 1751.135991 1683.124229 0.994695126 1.094553046 1.029590508 0.962299966 0.935637993 1.112179377 1.135543835 1.206881007 1.040408046 1 10.71692595 -5.031801001 3.499545265 1.001191213 1.167245453 0.689573736 0.044782526 0.092328739 2.338991374 0.006246419 0.019022587 9.29E-06 5.031801001 0.16605424 GPASQFYITPSTS(ph)LSPR ddPTM_HeLa_Curcumin_4h_R1 1 GPASQFYITPSTSLSPR 17 0 H0YIQ2;P49750-3;P49750-1;P49750 H0YIQ2 YLPM1 YLP motif-containing protein 1 1 0 GPASQFYIT(0.001)PS(0.015)T(0.282)S(0.693)LS(0.01)PR 150.69 0.00021457 43827000 2309.9 1656.4 1566.6 1823.2 1578.1 2454.9 1876.7 1210.3 1853.7 1727.5 TRUE FALSE FALSE 2127.068978 1799.571835 1624.659574 1815.656081 1559.282188 1945.726068 1929.355151 1579.314898 1650.353748 1787.530496 1.189948357 1.006736298 0.908884955 1.015734325 0.872310817 1.088499509 1.079341111 0.883517737 0.923259072 1 10.80375214 -7.020294863 24.22365526 1.090152815 0.979848846 0 0.097371264 575.2143486 686566.8644 0.015887162 0.019595786 9.54E-08 7.020294863 -0.110303969 GPAST(ph)PTYS(ph)PAPTQPAPR ddPTM_HeLa_Curcumin_4h_R1 1 GPASTPTYSPAPTQPAPR 18 0 Q6P1N0;Q6P1N0-2;K7EJY5 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 2 0 GPAS(0.079)T(0.921)PT(0.178)Y(0.001)S(0.821)PAPTQPAPR 171.87 3.44E-05 13372000 2896 2325.4 2057.4 2686.1 2610.9 5197.5 5718.5 2268.1 2625.1 1914.7 TRUE FALSE FALSE 2666.778544 2526.397214 2133.649054 2674.98563 2579.766723 4119.479912 5878.945719 2959.633249 2337.133098 1981.235682 1.346017825 1.275162383 1.076928441 1.350160233 1.302099869 2.079247789 2.967312658 1.493831993 1.179634063 1 10.95218479 -5.242680064 3.571844231 1.186325664 2.290876889 0.616673933 0.347795335 0.098903859 2.718561853 0.046161329 0.121386774 5.72E-06 5.242680064 1.104551225 GPASTPT(ph)YSPAPTQPAPR ddPTM_HeLa_Curcumin_4h_R1 1 GPASTPTYSPAPTQPAPR 18 0 Q6P1N0;Q6P1N0-2;K7EJY5 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 1 0 GPAS(0.073)T(0.073)PT(0.427)YS(0.427)PAPTQPAPR 317.03 2.45E-179 0 1037.9 945.7 1024 1103.3 1205.6 1757.7 1174.8 669.07 1224 928.69 TRUE FALSE FALSE 955.7491198 1027.442094 1061.950341 1098.734837 1191.224007 1393.133207 1207.761726 873.066363 1089.730262 960.9619084 0.994575447 1.069180875 1.105090984 1.143369812 1.239616261 1.449727814 1.256825807 0.908533788 1.133999436 1 9.908335435 -6.502009035 1.31567443 0.998089796 1.227377788 0.201674476 0.132263044 0.319441918 1.103263599 0.021571005 0.036655018 3.15E-07 6.502009035 0.229287992 GPASTPTYS(ph)PAPTQPAPR ddPTM_HeLa_Curcumin_4h_R1 1 GPASTPTYSPAPTQPAPR 18 0 Q6P1N0;Q6P1N0-2;K7EJY5 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 1 0 GPASTPT(0.002)YS(0.997)PAPT(0.001)QPAPR 186.96 1.41E-07 27268000 1657.1 1367.1 1439.5 1761.2 1502.8 2731.6 1540.5 801.59 1859.1 1226.2 TRUE FALSE FALSE 1525.938786 1485.266032 1492.849136 1753.912621 1484.880092 2165.035369 1583.722284 1045.991101 1655.161381 1268.810359 1.202653159 1.170597341 1.176573888 1.382328422 1.170293166 1.706350641 1.248194636 0.824387265 1.304498635 1 10.30926074 -8.586613279 0.481342174 0.982154525 1.27201553 0 0.225941595 1.489962102 0.674575482 0.195695911 0.065358606 2.59E-09 8.586613279 0.289861005 GPDEAMEDGEEGS(ph)DDEAEWVVTK ddPTM_HeLa_Curcumin_4h_R1 9 GPDEAMEDGEEGSDDEAEWVVTK 23 0 Q9NZN4-2;Q9NZN4 Q9NZN4-2 EHD2 EH domain-containing protein 2 1 0 GPDEAMEDGEEGS(0.999)DDEAEWVVT(0.001)K;GPDEAMEDGEEGS(0.999)DDEAEWVVT(0.001)K;GPDEAMEDGEEGS(0.998)DDEAEWVVT(0.002)K;GPDEAMEDGEEGS(1)DDEAEWVVTK;GPDEAMEDGEEGS(0.996)DDEAEWVVT(0.004)K;GPDEAMEDGEEGS(1)DDEAEWVVTK;GPDEAMEDGEEGS(1)DDEAEWVVTK;GPDEAMEDGEEGS(1)DDEAEWVVTK;GPDEAMEDGEEGS(1)DDEAEWVVTK ;;;;;;;; 124.28 2.55E-06 325218400 39954.3 33070.73 37980.8 36889.6 45056.7 46770.4 36803.12 35180.81 35206.06 29019.1 TRUE FALSE FALSE 36791.875 35929.21654 39388.40186 36736.96061 44519.42828 37069.69183 37835.7165 45907.27702 31344.0433 30027.51157 1.225272195 1.196543259 1.311743791 1.223443392 1.482621302 1.234524271 1.260035032 1.528840541 1.043844184 1 14.8739973 -12.92002094 0.086014807 2.82E-12 1.625882115 0.670431253 0.089892153 54.92522044 0.407513134 10.71865295 1.281450532 1.20E-13 12.92002094 1.625882115 GPDEAMEDGEEGS(ph)DDEAEWVVTKDK ddPTM_HeLa_Curcumin_4h_R1 3 GPDEAMEDGEEGSDDEAEWVVTKDK 25 1 Q9NZN4-2;Q9NZN4 Q9NZN4-2 EHD2 EH domain-containing protein 2 1 0 GPDEAMEDGEEGS(1)DDEAEWVVTKDK;GPDEAMEDGEEGS(0.999)DDEAEWVVT(0.001)KDK;GPDEAMEDGEEGS(1)DDEAEWVVTKDK ;; 112.8 4.19E-08 108383000 10239.7 6533.4 5586.8 8242.3 4114.6 9459 5351.97 6211.9 13593.9 10869.7 TRUE FALSE FALSE 9429.21694 7098.117984 5793.851723 8208.195547 4065.536082 7497.096775 5502.131874 8105.879714 12102.68318 11247.42127 0.838344783 0.631088479 0.51512712 0.729784664 0.36146384 0.666561392 0.489190521 0.720687838 1.076040711 1 13.45730665 -7.467134907 1.081168354 0.955667408 0.568276545 0.700695587 0.116167275 0.166512694 0.390037111 0.022868194 0.024590144 3.41E-08 7.467134907 -0.387390863 T(ph)SPSVTPTPAR ddPTM_HeLa_Curcumin_4h_R1 2 TSPSVTPTPAR 11 0 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 0 T(0.5)S(0.5)PSVTPTPAR;T(0.923)S(0.077)PSVTPTPAR ; 163.12 0.00085201 54158000 6144.8 5547 5726.3 6009.7 5859.3 6176.4 3676.6 1811.64 6991.6 5616.3 TRUE FALSE FALSE 5658.432596 6026.457963 5938.521715 5984.833454 5789.431674 4895.345018 3779.755501 2364.000696 6224.638972 5811.466007 0.973666987 1.036994444 1.021862936 1.029831964 0.996208473 0.842359744 0.650396216 0.40678216 1.071096168 1 12.50468643 -4.569231244 1.374575009 0.998641205 0.325896644 0.97332613 0.033200235 0.072546862 0.177048462 0.004274969 0.057538165 2.70E-05 4.569231244 -0.67274456 down GSPTDAEGS(ph)PGLSR ddPTM_HeLa_Curcumin_4h_R1 2 GSPTDAEGSPGLSR 14 0 Q8TER5;Q8TER5-4;Q8TER5-3;G3V485;G3V3N2;G3V5C1 Q8TER5 ARHGEF40 Rho guanine nucleotide exchange factor 40 1 0 GSPTDAEGS(1)PGLSR;GSPT(0.001)DAEGS(0.999)PGLSR ; 204.23 4.84E-09 154836000 6665.2 4449.2 5007.1 5054.4 5169.4 5296.4 2833.8 370.64 5901.1 5000.4 TRUE FALSE FALSE 6137.642387 4833.769023 5192.667531 5033.486232 5107.758281 4197.866937 2913.308801 483.6464298 5253.764094 5174.163528 1.186209588 0.93421265 1.003576231 0.972811587 0.987165994 0.811313155 0.563049232 0.093473356 1.015384239 1 12.33710994 -4.566914891 1.168149397 1.063484365 7.00E-27 0.933466765 0.076655691 0.200561332 0.31814594 0.014161815 0.226027459 2.71E-05 4.566914891 -1.063484365 down GPEENYSRPEAPNEFYDGDHDNDKES(ph)DVEI ddPTM_HeLa_Curcumin_4h_R1 2 GPEENYSRPEAPNEFYDGDHDNDKESDVEI 30 2 O15379;O15379-2 O15379 HDAC3 Histone deacetylase 3 1 0 GPEENYSRPEAPNEFY(0.001)DGDHDNDKES(0.999)DVEI;GPEENYSRPEAPNEFY(0.009)DGDHDNDKES(0.99)DVEI ; 47.331 0.0061946 59556000 6317.7 6587.3 7152.4 6721.8 9015.7 7956.4 6440 4243.5 6466.9 6334.6 TRUE FALSE FALSE 5817.647379 7156.67686 7417.474236 6693.986973 8908.193666 6306.152953 6620.689068 5537.323615 5757.497249 6554.726878 0.887549929 1.091834487 1.131622167 1.021245751 1.359048795 0.96207715 1.010063301 0.844783271 0.878373326 1 12.67831995 -7.250900918 24.45540403 0.946898577 1.067157001 0.184895397 0.129175338 730.7224903 1695704.26 0.021461864 0.026133302 5.61E-08 7.250900918 0.120258424 SDK(ac)PDMAEIEKFDK(ac)SK ddPTM_HeLa_Curcumin_4h_R1 2 SDKPDMAEIEKFDKSK 16 3 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 2 ; SDK(1)PDMAEIEK(0.107)FDK(0.893)SK;SDK(1)PDMAEIEK(0.003)FDK(0.997)SK 107.51 0.00095113 26292000 10117.9 8029.2 7799.4 8211.4 7158.5 12415.1 10032.4 18053.5 10218.2 8006.3 FALSE TRUE FALSE 9317.057539 8723.208271 8088.452625 8177.423403 7073.139563 9840.068313 10313.88214 23557.92904 9097.289025 8284.518329 1.124634791 1.052952981 0.976333482 0.987072884 0.853778009 1.187765893 1.244958576 2.843608778 1.098107176 1 13.0162021 -4.221728281 2.786618995 1.04176268 3.28421949 0.973730487 0.088520927 0.059483035 0.571481905 0.013137475 0.316313965 6.00E-05 4.221728281 2.24245681 up GPETEGEDAS(ph)PSALVVGPPETK ddPTM_HeLa_Curcumin_4h_R1 1 GPETEGEDASPSALVVGPPETK 22 0 A0A1B0GTL5 A0A1B0GTL5 1 0 GPET(0.01)EGEDAS(0.987)PS(0.003)ALVVGPPETK 112.26 8.86E-06 2323900 1899 1925.3 1941 2001 2254.5 2217.2 1664.2 1748.1 1894.7 1541.2 TRUE FALSE FALSE 1748.692146 2091.714353 2012.935167 1992.720392 2227.61656 1757.327727 1710.892973 2281.087643 1686.85615 1594.756585 1.096526054 1.311619825 1.262220947 1.249545172 1.396837975 1.101941038 1.072823896 1.430367282 1.057751488 1 10.63912052 -7.472654952 2.798815682 1.03800211 1.252118803 0.444525668 0.107304981 0.175800778 2.672841838 0.019576587 0.0215794 3.37E-08 7.472654952 0.214116692 GPGDLMGPQGLS(ph)PEEMAR ddPTM_HeLa_Curcumin_4h_R1 3 GPGDLMGPQGLSPEEMAR 18 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 0 GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR;GPGDLMGPQGLS(1)PEEMAR ;; 160.47 3.34E-05 35064000 6148.9 5326 5450.92 6069.5 6391.5 7549.4 5366.9 4004.04 5513.5 5320.05 TRUE FALSE FALSE 5662.208077 5786.355708 5652.93589 6044.386017 6315.285537 5983.569341 5517.48077 5224.853364 4908.682844 5504.921342 1.028572022 1.051124139 1.026887677 1.0979968 1.147207225 1.086949108 1.002281491 0.949124073 0.891689915 1 12.42650623 -7.663323997 0.976840319 1.007139335 1.057001321 0.196146502 0.062995847 0.741402969 1.475420666 0.013791501 0.013229948 2.17E-08 7.663323997 0.049861986 GPGEPDS(ph)PTPLHPPT(ph)PPILSTDR ddPTM_HeLa_Curcumin_4h_R1 1 GPGEPDSPTPLHPPTPPILSTDR 23 0 Q03164-2;Q03164;Q03164-3 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 2 0 GPGEPDS(0.777)PT(0.224)PLHPPT(0.937)PPILS(0.033)T(0.03)DR 61.911 0.0062242 2919200 425.86 331.91 376.67 328.83 463.83 580.56 597.95 435.1 566.3 393.89 TRUE FALSE FALSE 392.1527316 360.5988214 390.6297216 327.4693886 458.2991302 460.1453117 614.7268677 567.759987 504.1783068 407.5776482 0.962154655 0.884736499 0.958417919 0.803452766 1.124446182 1.128975825 1.508244798 1.393010607 1.237011669 1 8.670931125 -5.000608438 1.853765032 0.963434832 1.463717029 0.682853901 0.120264588 0.096253951 0.623222184 0.011606188 0.050225637 9.99E-06 5.000608438 0.500282197 GPGGS(ph)QGSQGPSPQGAR ddPTM_HeLa_Curcumin_4h_R1 1 GPGGSQGSQGPSPQGAR 17 0 Q96MG7 Q96MG7 NDNL2 Melanoma-associated antigen G1 1 0 GPGGS(0.999)QGS(0.001)QGPSPQGAR 115.53 0.0016502 0 324.56 238.42 305.16 294.7 345.87 216.48 405.59 348.64 375.88 349.16 TRUE FALSE FALSE 298.8707335 259.0279624 316.469498 293.4806095 341.7457261 171.5796078 416.9697638 454.9387311 334.6469044 361.293284 0.827224714 0.716946519 0.875935181 0.812305743 0.945895596 0.47490395 1.154103279 1.259195095 0.926247232 1 8.497026627 -4.545272979 24.9963598 0.868070589 1.232922547 0.516779401 0.144843127 125.1950626 139742.1415 0.020548383 0.07689517 2.85E-05 4.545272979 0.364851958 GPGGSQGS(ph)QGPSPQGAR ddPTM_HeLa_Curcumin_4h_R1 1 GPGGSQGSQGPSPQGAR 17 0 Q96MG7 Q96MG7 NDNL2 Melanoma-associated antigen G1 1 0 GPGGS(0.005)QGS(0.988)QGPS(0.007)PQGAR 71.402 0.01802 597840 0 183.58 168.96 157.2 176.29 179.56 288.63 194.15 143.63 140.15 TRUE FALSE FALSE 0 199.4478372 175.2218062 156.5495481 174.1878569 142.3172319 296.728181 253.3454412 127.8741483 145.0202021 0 1.375310711 1.20825791 1.079501654 1.201128218 0.981361424 2.046116174 1.746966544 0.881767826 1 7.180110079 -5.324695068 0.542761226 0.579389264 2.065161945 0.386853625 0.404344385 1.153941262 0.441199898 0.11105829 0.885107446 4.73E-06 5.324695068 1.485772681 GPGGSQGSQGPS(ph)PQGAR ddPTM_HeLa_Curcumin_4h_R1 4 GPGGSQGSQGPSPQGAR 17 0 Q96MG7 Q96MG7 NDNL2 Melanoma-associated antigen G1 1 0 GPGGSQGSQGPS(1)PQGAR;GPGGSQGSQGPS(1)PQGAR;GPGGSQGS(0.008)QGPS(0.992)PQGAR;GPGGSQGSQGPS(1)PQGAR ;;; 238.05 2.81E-30 66631000 4001.46 3295.14 3612.85 3734.01 3725.6 4298.53 2991.52 1969.81 3895.3 3711.22 TRUE FALSE FALSE 3684.740219 3579.957219 3746.745399 3718.559656 3681.174653 3406.966424 3075.454 2570.396001 3467.995336 3840.184619 0.959521634 0.932235706 0.97566804 0.968328355 0.958593146 0.887188185 0.800860976 0.669341778 0.903080367 1 11.90695996 -4.276626132 0.912696535 0.977017339 0.498197169 0.908064728 0.028974155 0.290149853 0.182016146 0.003395429 0.137122657 5.29E-05 4.276626132 -0.47882017 GPGKMSHS(ph)S(ph)S(ph)GPAS(ph)VS(ph)QLSSWK ddPTM_HeLa_Curcumin_4h_R1 1 GPGKMSHSSSGPASVSQLSSWK 22 1 P0C7V6;Q3ZLR7 P0C7V6 SUPT20HL2;SUPT20HL1 Putative transcription factor SPT20 homolog-like 2;Transcription factor SPT20 homolog-like 1 5 0 GPGKMS(0.205)HS(0.86)S(0.964)S(0.964)GPAS(0.974)VS(0.742)QLS(0.146)S(0.146)WK 43.955 0.0094687 0 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 GPGPGQGS(ph)PGGGPGPR ddPTM_HeLa_Curcumin_4h_R1 2 GPGPGQGSPGGGPGPR 16 0 H0YDS2;Q8IYL2 H0YDS2 TRMT44 Probable tRNA (uracil-O(2)-)-methyltransferase 1 0 GPGPGQGS(1)PGGGPGPR;GPGPGQGS(1)PGGGPGPR ; 86.367 0.0082582 13195000 3268.4 2697.8 3273 3034.1 3050.5 2996.1 1856.61 1529.24 3264.4 2689.2 TRUE FALSE FALSE 3009.702691 2930.985811 3394.300259 3021.545698 3014.12478 2374.675087 1908.70148 1995.498236 2906.303487 2782.6495 1.081596044 1.05330758 1.219808768 1.085852062 1.083185209 0.853386345 0.685929536 0.717121663 1.0444375 1 11.44224348 -5.049037033 2.868784311 1.060720574 0.70265348 0.87910532 0.057255487 0.076104204 1.231920289 0.009650903 0.031012061 8.93E-06 5.049037033 -0.358067094 GPGQPS(ph)SPQRLDR ddPTM_HeLa_Curcumin_4h_R1 1 GPGQPSSPQRLDR 13 1 O95400 O95400 CD2BP2 CD2 antigen cytoplasmic tail-binding protein 2 1 0 GPGQPS(0.5)S(0.5)PQRLDR 67.136 0.017412 57286000 3067.8 2517.9 2619.2 2461.1 2825.7 3617.3 2309.3 2015.1 3218.1 2549.1 TRUE FALSE FALSE 2824.980393 2735.536056 2716.269856 2450.91662 2792.005373 2867.031205 2374.092743 2629.494714 2865.082481 2637.681035 1.0710091 1.037098883 1.029794664 0.929193707 1.058507581 1.086951442 0.90006817 0.996896394 1.08621264 1 11.3650544 -6.489163737 24.93614199 1.034675108 0.995968373 0.159098659 0.055704714 1148.744752 849628.4721 0.008642282 0.013197136 3.24E-07 6.489163737 -0.038706736 GPGQPSS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 2 GPGQPSSPQR 10 0 O95400 O95400 CD2BP2 CD2 antigen cytoplasmic tail-binding protein 2 1 0 GPGQPS(0.005)S(0.995)PQR;GPGQPS(0.001)S(0.999)PQR ; 104.07 0.01016 63244000 12306.5 10344.7 11297.5 10834 15068.4 15961.9 12314.2 11344.9 10490.1 9989.5 TRUE FALSE FALSE 11332.42754 11238.84977 11716.19529 10789.17178 14888.71917 12651.22201 12659.70331 14803.90778 9339.362275 10336.63438 1.096336305 1.087283284 1.133463259 1.043779956 1.440383651 1.223920818 1.224741327 1.432178719 0.903520617 1 13.3354789 -1 0.176100444 0.974377762 2.72981095 0.660432928 0.096789465 25.84154177 0.277098685 0.117977539 12.13548533 0.1 1 1.755433189 GPGQVPTATSALSLELQEVEPLGLPQAS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 GPGQVPTATSALSLELQEVEPLGLPQASPSR 31 0 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 0 GPGQVPTATSALSLELQEVEPLGLPQAS(0.568)PS(0.432)R 72.838 3.30E-05 2603200 1534.1 1208.2 1106.7 1064.9 1070.1 905.28 552.62 647.85 1347.8 1308.3 TRUE FALSE FALSE 1412.674366 1312.631424 1147.715276 1060.493726 1057.339756 717.5147234 568.1250299 845.3764827 1199.949712 1353.763328 1.043516498 0.969616622 0.847796104 0.783367155 0.781037375 0.530014892 0.419663481 0.624464015 0.886380719 1 10.40275983 -5.82348667 0.809082676 1.021775766 0.484849306 0.834299821 0.079924413 0.141624459 0.171380525 0.012256081 0.04228815 1.50E-06 5.82348667 -0.53692646 GPHHLDNSS(ph)PGPGSEAR ddPTM_HeLa_Curcumin_4h_R1 3 GPHHLDNSSPGPGSEAR 17 0 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3;H3BUF6 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 0 GPHHLDNS(0.037)S(0.911)PGPGS(0.052)EAR;GPHHLDNS(0.184)S(0.812)PGPGS(0.004)EAR;GPHHLDNS(0.203)S(0.796)PGPGS(0.001)EAR ;; 165.49 5.13E-05 32966000 6015 6421.8 6091.9 6235.5 6877.2 11771.8 9424.3 3189.76 6753.1 5063.6 TRUE FALSE FALSE 5538.906403 6976.871777 6317.671173 6209.699153 6795.193882 9330.195984 9688.720494 4162.30314 6012.301825 5239.559723 1.057132029 1.331575962 1.205763749 1.18515667 1.296901694 1.780721373 1.84914783 0.794399408 1.147482259 1 12.35522987 -6.5490792 0.689291563 1.013855179 1.480867903 0.168226459 0.284227374 0.622143253 0.594662232 0.061710696 0.12346977 2.82E-07 6.5490792 0.467012724 GPKPEPPGS(ph)GSPAPPR ddPTM_HeLa_Curcumin_4h_R1 1 GPKPEPPGSGSPAPPR 16 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 0 GPKPEPPGS(0.5)GS(0.5)PAPPR 86.189 0.0036633 43659000 3378 3713.3 2500.4 3569.7 3005.2 3649.3 2712.2 1848.8 3067.6 2651.8 TRUE FALSE FALSE 3110.627736 4034.261106 2593.067024 3554.929527 2969.364953 2892.394044 2788.297032 2412.490609 2731.091955 2743.949853 1.133631408 1.470238642 0.945012541 1.29555193 1.082149861 1.054098726 1.016161804 0.879203607 0.995314092 1 11.4220384 -4.309351692 1.400428256 1.104471478 0.802404759 0.205869594 0.148577169 1.554700946 2.853474155 0.021556203 0.641352752 4.91E-05 4.309351692 -0.302066719 GPKPEPPGSGS(ph)PAPPR ddPTM_HeLa_Curcumin_4h_R1 1 GPKPEPPGSGSPAPPR 16 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 0 GPKPEPPGS(0.139)GS(0.861)PAPPR 111.58 0.014411 32297000 2699.1 2322.6 2194.8 2531.1 2822.2 2986.7 2574 1715.5 2464.9 2343.8 TRUE FALSE FALSE 2485.463387 2523.355195 2276.141219 2520.626979 2788.547108 2367.224753 2646.219512 2238.548053 2194.506637 2425.246876 1.024829023 1.040452921 0.93851939 1.039327998 1.149799279 0.976075787 1.091113461 0.923018632 0.904859072 1 11.2439159 -9.082352989 0.404755555 0.993593442 1.02898608 0.058461668 0.070705587 7.911679576 1.893400766 0.119974386 0.022136719 8.27E-10 9.082352989 0.035392638 GPKS(ph)DDDGFEIVPIEDPAK ddPTM_HeLa_Curcumin_4h_R1 1 GPKSDDDGFEIVPIEDPAK 19 1 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 0 GPKS(1)DDDGFEIVPIEDPAK 84.156 0.0015138 9029300 5861.5 5882.5 6125 6229.2 6004.5 6741.4 5717.6 3509.9 5655.8 5817.1 TRUE FALSE FALSE 5397.55609 6390.957088 6351.997888 6203.425221 5932.900259 5343.157649 5878.020468 4580.052352 5035.37289 6019.243792 0.896716644 1.061754152 1.055281711 1.030598765 0.985655419 0.887679222 0.976538029 0.76090162 0.836545763 1 12.55536653 -3.61166559 1.458312467 0.971630795 5.47E-13 0.426923595 0.071773575 4.942572288 2.402863644 0.009866107 11.16069313 0.000244531 3.61166559 -0.971630795 GPKVDIDT(ph)PDINIEGSEGK ddPTM_HeLa_Curcumin_4h_R1 2 GPKVDIDTPDINIEGSEGK 19 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GPKVDIDT(1)PDINIEGSEGK;GPKVDIDT(1)PDINIEGSEGK ; 103.25 0.00060983 28283000 9175.9 5005.2 6583.1 8518.3 4708.8 8170 7845.2 10064.5 8814.3 6867.7 TRUE FALSE FALSE 8449.617833 5437.827185 6827.075477 8483.053532 4652.650635 6475.449905 8065.315198 13133.11972 7847.393342 7106.352064 1.189023251 0.765206556 0.960700429 1.193728295 0.654717159 0.911219969 1.134944501 1.848081773 1.104278717 1 12.79489345 -4.27117167 3.707652885 1.025402836 1.928113448 0.6991838 0.16880964 0.119616852 3.074928459 0.02487667 0.291584522 5.36E-05 4.27117167 0.902710612 GPLATGGIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 GPLATGGIKK 10 1 Q9Y2S6;A0A024R1R8 Q9Y2S6 TMA7;hCG_2014768 Translation machinery-associated protein 7 0 1 ; GPLATGGIK(1)K;GPLATGGIK(1)K 83.647 0.011458 20118600 7458.1 5964.1 6333.4 5886.8 7684.6 10605.9 8483.3 9185.4 8519.8 6466.6 FALSE TRUE FALSE 6867.783515 6479.610228 6568.121375 5862.441981 7592.966164 8406.116787 8721.318566 11985.98618 7585.199255 6691.313869 1.026372944 0.968361424 0.981589192 0.876127185 1.134749664 1.256272976 1.303379088 1.791275437 1.133588919 1 12.7080738 -3.542999655 0.763776721 0.99910397 3.51597498 0.90168955 0.07811109 1.172074411 0.22422639 0.010803126 3.27016314 0.000286418 3.542999655 2.51687101 GPLPVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GPLPVKR 7 1 P38159;P38159-2;H3BUY5;Q96E39;H0Y6E7;H3BT71;A0A1B0GUK8 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 0 1 ; GPLPVK(1)R;GPLPVK(1)R 101.33 0.0068186 257540000 9748.3 7133.1 8031.8 6317.5 7459.8 10916.8 7338.5 7169.6 8969.6 7937.3 FALSE TRUE FALSE 8976.711769 7749.65338 8329.465573 6291.359859 7370.846757 8652.532622 7544.398559 9355.578035 7985.657321 8213.120584 1.092972114 0.943569901 1.014165747 0.766013331 0.897447771 1.053501228 0.918578813 1.139101507 0.972304892 1 13.00371476 -7.245259461 23.97449017 1.043903499 0.955647755 0.056651307 0.098480954 672.6822158 996742.2839 0.016086232 0.019664597 5.69E-08 7.245259461 -0.088255744 DLLSDLQDISDS(ph)ERK ddPTM_HeLa_Curcumin_4h_R1 1 DLLSDLQDISDSERK 15 1 Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;J3KS35;E7ESP2;P21127-5;P21127-10;A0A0D9SEI3;A0A0D9SER5;A0A0D9SEN2;P21127-6;P21127-9;P21127-8;P21127-3;P21127-2;P21127;Q9UQ88-9 Q5QPR4;A0A0D9SEI3 CDK11A;CDK11B Cyclin-dependent kinase 11A;Cyclin-dependent kinase 11B 1 0 DLLSDLQDIS(0.015)DS(0.985)ERK 122.19 0.00054304 7222600 4795 3875.4 4209.8 4197 3448 4153.6 2606.9 1396.4 4983.9 3997.6 TRUE FALSE FALSE 4415.47069 4210.372308 4365.818891 4179.633926 3406.884852 3292.096539 2680.042598 1822.155932 4437.178639 4136.516302 1.067437033 1.017854639 1.055433745 1.010423656 0.823612094 0.795862097 0.647898473 0.440504956 1.072684915 1 12.01420055 -4.562492515 0.728178004 1.036549226 0.236262841 0.961908368 0.03947096 0.274241753 0.130963315 0.007262168 0.164173896 2.74E-05 4.562492515 -0.800286385 down GPPAS(ph)SPAPAPK ddPTM_HeLa_Curcumin_4h_R1 1 GPPASSPAPAPK 12 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 0 GPPAS(0.523)S(0.477)PAPAPK 113.63 0.0045006 3350100 3313.1 2626.3 2991.6 3066.3 3151.6 2221 1373.8 1039.3 3034.5 2467.4 TRUE FALSE FALSE 3050.864639 2853.305669 3102.471328 3053.612463 3114.019228 1760.339564 1412.345131 1356.177786 2701.622942 2553.141966 1.194945161 1.117566397 1.215158173 1.196021413 1.219681189 0.689479703 0.553179239 0.531179936 1.058156177 1 11.31805805 -5.134574011 3.991462546 1.120534157 0.556727926 0.924890988 0.072457856 0.058232795 1.58839038 0.013747698 0.037704078 7.34E-06 5.134574011 -0.56380623 GPPASS(ph)PAPAPK ddPTM_HeLa_Curcumin_4h_R1 5 GPPASSPAPAPK 12 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 0 GPPAS(0.039)S(0.961)PAPAPK;GPPAS(0.047)S(0.953)PAPAPK;GPPAS(0.17)S(0.83)PAPAPK;GPPAS(0.043)S(0.957)PAPAPK;GPPAS(0.131)S(0.869)PAPAPK ;;;; 160.72 0.00020338 1838222400 35713.4 30181.3 31219 32798.3 31757.8 21865.5 13518.5 10680.7 32577.5 26780.8 TRUE FALSE FALSE 32886.64671 32790.03709 32376.0036 32662.58933 31379.10898 17330.34883 13897.79273 13937.19626 29003.82975 27711.43081 1.186753832 1.183267559 1.168326667 1.178668455 1.132352537 0.625386287 0.50151841 0.502940334 1.046637756 1 14.75819358 -5.190883668 3.771934635 1.113864295 0.514994158 0.950169286 0.061613279 0.049360738 1.372469868 0.012344501 0.033403328 6.44E-06 5.190883668 -0.598870137 GPPASS(ph)PAPAPKFS(ph)PVTPK ddPTM_HeLa_Curcumin_4h_R1 2 GPPASSPAPAPKFSPVTPK 19 1 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 2 0 GPPAS(0.129)S(0.871)PAPAPKFS(0.882)PVT(0.119)PK;GPPAS(0.257)S(0.729)PAPAPKFS(0.958)PVT(0.056)PK ; 70.569 0.0072399 214070000 8610.8 6474.3 6714.5 7206.1 7184.5 8280.5 6464.4 5062.3 8981.8 6346.5 TRUE FALSE FALSE 7929.246094 7033.909643 6963.345277 7176.283068 7098.82953 6563.03096 6645.773666 6605.771966 7996.519011 6567.040403 1.207430685 1.071092792 1.060347561 1.092772791 1.080978507 0.99938946 1.011989155 1.005897872 1.217674709 1 12.68102762 -5.324577834 4.20994813 1.09424865 1.005995812 0.338163655 0.062256489 0.269074733 9.578968708 0.011048248 0.026241767 4.74E-06 5.324577834 -0.088252837 GPPASSPAPAPK ddPTM_HeLa_Curcumin_4h_R1 2 GPPASSPAPAPK 12 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 0 0 ; ; 117.71 0.0012547 3904900 3401.6 2520.4 2759.6 2666 2881.2 3796.7 3045.7 3337.1 3361 2930.3 FALSE FALSE TRUE 3132.359771 2738.252145 2861.873204 2654.968798 2846.843572 3009.221622 3131.154145 4354.566428 2992.306709 3032.127707 1.033056676 0.903079425 0.943849824 0.875612459 0.938893031 0.992445541 1.032659059 1.436142158 0.986866979 1 11.5661148 -4.254121124 3.492274497 0.986427847 1.494762009 0.884305581 0.050716971 0.091695151 1.900899358 0.008558287 0.123712281 5.57E-05 4.254121124 0.508334161 GPPASSPAPAPKFS(ph)PVTPK ddPTM_HeLa_Curcumin_4h_R1 2 GPPASSPAPAPKFSPVTPK 19 1 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 0 GPPAS(0.001)SPAPAPKFS(0.918)PVT(0.081)PK;GPPASSPAPAPKFS(0.987)PVT(0.013)PK ; 100.14 0.00043715 1410310000 6114.7 4416.4 4899.6 5748.4 4542.5 4953.9 2648.7 2741.3 7095.6 5142.7 TRUE FALSE FALSE 5630.715043 4798.133937 5081.183486 5724.614644 4488.333654 3926.405298 2723.015393 3577.109751 6317.230432 5321.408442 1.05812495 0.901666164 0.954856884 1.07577058 0.843448441 0.737850767 0.511709526 0.672211086 1.187135042 1 12.37759243 -5.30754676 1.803278108 1.014821796 0.5940903 0.803496844 0.086773045 0.087525245 0.542363748 0.009841486 0.031376925 4.93E-06 5.30754676 -0.420731496 APS(ph)VPAAEPEYPK ddPTM_HeLa_Curcumin_4h_R1 1 APSVPAAEPEYPK 13 0 F8VPP1;G3V213;F8VZG5;A0A5F9ZHP2;F8VY04;A0A5K1VW67;F8W1A4;P54819-3;P54819-5;P54819-2;P54819 F8VPP1 AK2 "Adenylate kinase 2, mitochondrial;Adenylate kinase 2, mitochondrial;Adenylate kinase 2, mitochondrial, N-terminally processed" 1 0 APS(1)VPAAEPEYPK 82.202 0.019977 8423800 2745.4 2366.2 2548.9 2515.8 2852.6 3578.6 1678.4 803.77 3013.7 2472 TRUE FALSE FALSE 2528.098693 2570.723784 2643.364476 2505.390286 2818.584608 2836.358021 1725.491387 1048.835773 2683.10465 2557.901816 0.988348606 1.00501269 1.033411236 0.979470858 1.101912744 1.108861178 0.674572955 0.410037542 1.048947474 1 11.32074517 -4.557436607 3.52121826 1.010258865 0.443451622 0.939002451 0.051695185 0.038644915 0.959295585 0.007532158 0.039618343 2.77E-05 4.557436607 -0.566807243 down GPPDFS(ph)S(ph)DEEREPTPVLGSGAAAAGR ddPTM_HeLa_Curcumin_4h_R1 2 GPPDFSSDEEREPTPVLGSGAAAAGR 26 1 G5E972;P42167;P42167-3;P42167-2;P42166 G5E972;P42166 TMPO "Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin" 2 0 GPPDFS(0.998)S(0.998)DEEREPT(0.003)PVLGS(0.001)GAAAAGR;GPPDFS(0.969)S(0.975)DEEREPT(0.044)PVLGS(0.012)GAAAAGR ; 54.263 0.0053651 260926000 5268.1 4343.2 4714.8 5213.9 4629.9 5878.9 3674 2246.36 5792 5012.4 TRUE FALSE FALSE 4851.124326 4718.606855 4889.534636 5192.326263 4574.691466 4659.549871 3777.082552 2931.264823 5156.632091 5186.580527 0.93532228 0.909772215 0.94272799 1.001107808 0.882024571 0.898385718 0.728241378 0.565163272 0.994225784 1 12.34056798 -4.179319712 0.912767391 0.963955478 0.282982511 0.929176535 0.034919118 0.447881251 0.252111616 0.005900034 0.313085777 6.62E-05 4.179319712 -0.680972967 GPPDFS(ph)SDEEREPT(ph)PVLGSGAAAAGR ddPTM_HeLa_Curcumin_4h_R1 1 GPPDFSSDEEREPTPVLGSGAAAAGR 26 1 G5E972;P42167;P42167-3;P42167-2;P42166 G5E972;P42166 TMPO "Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin" 2 0 GPPDFS(0.478)S(0.525)DEEREPT(0.899)PVLGS(0.098)GAAAAGR 58.251 0.008049 17916000 2958.7 3563.2 3580.4 4295.3 3197.1 3814.6 2084.1 990.13 5001.3 2850.8 TRUE FALSE FALSE 2724.515773 3871.187131 3713.092774 4277.527187 3158.976671 3023.408961 2142.574237 1292.016079 4452.669903 2949.865088 0.923606908 1.312326841 1.258733082 1.450075532 1.070888524 1.024931267 0.726329569 0.437991583 1.50944866 1 11.52643326 -4.527643024 2.184345188 1.056666563 0.416091589 0.500393063 0.221024061 0.259665466 2.00825818 0.029017254 0.258634193 2.97E-05 4.527643024 -0.640574974 GPPDFS(ph)SDEEREPTPVLGSGAAAAGR ddPTM_HeLa_Curcumin_4h_R1 2 GPPDFSSDEEREPTPVLGSGAAAAGR 26 1 G5E972;P42167;P42167-3;P42167-2;P42166 G5E972;P42166 TMPO "Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin" 1 0 GPPDFS(0.55)S(0.448)DEEREPT(0.002)PVLGSGAAAAGR;GPPDFS(0.557)S(0.443)DEEREPTPVLGSGAAAAGR ; 91.378 5.32E-06 807090000 1245.08 1000.17 1063.08 1187.97 1096 919.42 712.86 711.44 1223.43 976.27 TRUE FALSE FALSE 1146.530604 1086.620238 1102.47868 1183.054495 1082.930916 728.721928 732.860933 928.3547809 1089.22279 1010.19531 1.134959342 1.075653616 1.091352008 1.171114619 1.072001528 0.721367364 0.725464597 0.91898544 1.078229902 1 9.980418533 -5.269463837 24.59287938 1.076879886 0.782291678 0.81057595 0.066352673 162.9598012 499430.2119 0.010801561 0.024564626 5.38E-06 5.269463837 -0.294588209 GPPDFSSDEEREPT(ph)PVLGSGAAAAGR ddPTM_HeLa_Curcumin_4h_R1 2 GPPDFSSDEEREPTPVLGSGAAAAGR 26 1 G5E972;P42167;P42167-3;P42167-2;P42166 G5E972;P42166 TMPO "Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin" 1 0 GPPDFS(0.001)S(0.001)DEEREPT(0.966)PVLGS(0.032)GAAAAGR;GPPDFS(0.011)S(0.01)DEEREPT(0.978)PVLGS(0.001)GAAAAGR ; 80.453 8.47E-05 272210000 3377.5 3169.7 3270.9 4396.3 4179.4 5836.8 3300 774.57 5734.4 3664.6 TRUE FALSE FALSE 3110.167311 3443.674744 3392.122431 4378.109275 4129.563385 4626.181886 3392.589119 1010.732827 5105.350667 3791.944577 0.820203789 0.908155347 0.894560129 1.154581557 1.089035797 1.220002506 0.894683203 0.266547363 1.346367428 1 11.88872216 -4.270330421 4.727837376 0.960204202 0.23077821 0.61791167 0.173148508 0.07639528 4.698313604 0.019846635 0.180710854 5.37E-05 4.270330421 -0.729425993 GPPLREGEELVMDEEAYVLYHR ddPTM_HeLa_Curcumin_4h_R1 1 GPPLREGEELVMDEEAYVLYHR 22 1 Q9BQ67 Q9BQ67 GRWD1 Glutamate-rich WD repeat-containing protein 1 0 0 118.52 2.51E-06 2203000 496.85 408.58 347.94 466.13 325.91 597.19 380.69 322.67 559.2 508.17 FALSE FALSE TRUE 457.5237982 443.8958346 360.8349625 464.2012776 322.0237361 473.3260623 391.3711368 421.0505976 497.857159 525.8288697 0.870100188 0.84418308 0.686221285 0.882799147 0.61241167 0.900152292 0.744293742 0.800736935 0.946804536 1 9.038449542 -7.979486885 0.607846928 0.989845511 0.769973691 0.456361976 0.083504443 0.373033229 0.315605748 0.033050448 0.022105476 1.05E-08 7.979486885 -0.21987182 GPPNS(ph)PDLK ddPTM_HeLa_Curcumin_4h_R1 1 GPPNSPDLK 9 0 A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-1;M0QZS0;A0A590UK10;Q6ZSZ5-2;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 A0A3B3IPE9 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 0 GPPNS(1)PDLK 101.35 0.012339 25642000 3608 3017.8 3181 3129.6 3690.7 3731.6 2935.3 3030.4 3722.9 3393.7 TRUE FALSE FALSE 3322.422993 3278.645185 3298.890658 3116.650544 3646.690813 2957.624096 3017.656618 3954.35501 3314.507184 3511.630822 0.946119669 0.933653152 0.939418414 0.887522266 1.03846076 0.842236626 0.859331966 1.126073671 0.943865501 1 11.77792547 -8.893333464 0.727336286 1.000517021 0.940314336 0 0.08125963 1.512045263 1.478512013 0.050447509 0.016070358 1.28E-09 8.893333464 -0.060202685 GPPPSYGGSSR ddPTM_HeLa_Curcumin_4h_R1 1 GPPPSYGGSSR 11 0 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 0 0 112.11 0.0039056 1737600 140.77 214.26 119.05 215.79 212.01 179.15 150.49 123.35 155.26 0 FALSE FALSE TRUE 129.627906 232.7796797 123.4620977 214.8971182 209.4819192 141.9922706 154.7123444 160.9588472 138.2283664 0 0 GPPQEEEEEEDEEEEATKEDAEAPGIR ddPTM_HeLa_Curcumin_4h_R1 3 GPPQEEEEEEDEEEEATKEDAEAPGIR 27 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 0 0 ;; ;; 177.24 8.28E-15 72495000 3520.86 2815.08 3486.78 3189.72 4139.64 3907.87 3010.8 2731.46 3307.16 2568.14 FALSE FALSE TRUE 3242.180216 3058.402971 3616.003134 3176.521784 4090.277497 3097.333711 3095.274945 3564.26958 2944.372822 2657.382674 1.220065235 1.150907997 1.360738583 1.195357302 1.539212827 1.165558029 1.164783294 1.341270723 1.107997298 1 11.37579028 -8.762155175 0.457528596 0.965581211 1.288266646 0.358545324 0.11565813 0.894361788 0.332617299 0.130106177 0.035240494 1.73E-09 8.762155175 0.322685435 FSS(ph)PTEELDYR ddPTM_HeLa_Curcumin_4h_R1 2 FSSPTEELDYR 11 0 H0Y911;Q4VXL4;D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-2;O95359-6;O95359-1;O95359-5;O95359-3;O95359;E9PGB3 H0Y911 TACC2 Transforming acidic coiled-coil-containing protein 2 1 0 FS(0.062)S(0.914)PT(0.024)EELDYR;FS(0.02)S(0.839)PT(0.142)EELDYR ; 159.94 0.00035223 9527200 3607.2 3421.6 3560.5 3246.2 3818 4463.4 3638 7795.1 3847.5 3383.6 TRUE FALSE FALSE 3321.686314 3717.347858 3692.455262 3232.768085 3772.472844 3537.640527 3740.072489 10171.79011 3425.438876 3501.179848 0.948733415 1.061741475 1.054631702 0.923336768 1.077486164 1.010413826 1.068232039 2.905246387 0.978367015 1 11.77362546 -4.260868679 5.27282933 0.993739585 2.98585929 0.992944101 0.047851259 0.00907569 0.876661936 0.00702654 0.06521129 5.48E-05 4.260868679 1.992119704 up GPPS(ph)PPAPVMHS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 GPPSPPAPVMHSPSR 15 0 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 2 0 GPPS(1)PPAPVMHS(0.753)PS(0.247)R;GPPS(1)PPAPVMHS(0.941)PS(0.059)R ; 89.877 0.0093755 122722000 5198.8 4310.3 4921.7 4327.1 4711.2 6154.4 4240 3358.8 5401.1 4689.3 TRUE FALSE FALSE 4787.309494 4682.863126 5104.102532 4309.195607 4655.022017 4877.908066 4358.962989 4382.882658 4808.612843 4852.252826 0.986615839 0.965090504 1.051903665 0.888081426 0.959352734 1.005287284 0.898337977 0.903267578 0.991006243 1 12.24443901 -1 0.302769893 0.997580571 0.105837236 0.340379505 0.041210621 37.54065649 0.48022398 0.014294112 18.44224161 0.1 1 -0.891743336 GPPS(ph)PPAPVMHSPSRK ddPTM_HeLa_Curcumin_4h_R1 1 GPPSPPAPVMHSPSRK 16 1 G3V3A4;Q13573;G3V4X8 G3V3A4 SNW1 SNW domain-containing protein 1 1 0 GPPS(1)PPAPVMHSPSRK 98.882 0.0014992 8361700 2427.6 1567.5 1659.2 2023.2 1944.7 3301.6 1808.9 3934 2032.7 1660.1 TRUE FALSE FALSE 2235.452898 1702.987715 1720.691412 2014.828534 1921.510723 2616.810943 1859.652866 5133.45849 1809.717896 1717.788351 1.301355255 0.9913839 1.001689999 1.172920129 1.118595734 1.523360512 1.082585561 2.988411515 1.053516223 1 10.74633658 -4.260191248 24.90240181 1.148399191 2.988412143 0.925742606 0.157167128 20.01998807 399383.6224 0.023276123 0.193154017 5.49E-05 4.260191248 1.840012953 GPPVT(ph)PSSEKR ddPTM_HeLa_Curcumin_4h_R1 2 GPPVTPSSEKR 11 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 0 GPPVT(1)PSSEKR;GPPVT(0.963)PS(0.032)S(0.005)EKR ; 145.23 0.0099046 26936000 14654 12133.9 11906.5 13074.1 12880.2 13362.7 9629.9 7967.8 13611 12858 TRUE FALSE FALSE 13494.12044 13182.70025 12347.76536 13020.00284 12726.61203 10591.12539 9900.089076 10397.14554 12117.90735 13304.81454 1.014228375 0.990821797 0.928067454 0.978593335 0.956541858 0.796037055 0.744098239 0.781457382 0.910791151 1 13.69966078 -5.281922542 2.328830188 0.997399112 0.759422034 0.846339049 0.037131794 0.054416899 0.57174297 0.004160631 0.011982292 5.22E-06 5.281922542 -0.237977078 GPQGPSGPPGVPGS(ph)PGSSRPGLR ddPTM_HeLa_Curcumin_4h_R1 1 GPQGPSGPPGVPGSPGSSRPGLR 23 1 Q01955-5;Q01955-4;Q01955-3;Q01955-2;Q01955 Q01955-5 COL4A3 Collagen alpha-3(IV) chain;Tumstatin 1 0 GPQGPSGPPGVPGS(0.99)PGS(0.008)S(0.002)RPGLR 67.899 0.00087691 8818500 1223.1 802.27 895.41 947.49 1063.1 1194.7 1179.7 863.03 1001.7 1092.5 TRUE FALSE FALSE 1126.290344 871.614644 928.5946823 943.5695374 1050.423227 946.905753 1212.799207 1126.163874 891.8160161 1130.464294 0.996307757 0.771023595 0.821427698 0.834674339 0.929196289 0.83762553 1.07283283 0.996195882 0.788893573 1 10.14269971 -7.455255549 24.99746776 0.998371542 0.894714794 0 0.107066167 195.9526137 72435.56077 0.015100206 0.017267185 3.51E-08 7.455255549 -0.103656749 GPQPPTVS(ph)PIR ddPTM_HeLa_Curcumin_4h_R1 2 GPQPPTVSPIR 11 0 P46087;P46087-4;P46087-2 P46087;P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 0 GPQPPT(0.012)VS(0.988)PIR;GPQPPT(0.001)VS(0.999)PIR ; 124.81 0.0035728 370400000 4526.4 4200.2 4355.6 4764.8 4938 5773.3 3899 1980.62 4381.8 3888.5 TRUE FALSE FALSE 4168.130664 4563.246572 4517.022368 4745.08452 4879.117575 4575.852501 4008.395446 2584.50192 3901.127503 4023.625086 1.035914275 1.134113262 1.122625064 1.17930583 1.212617347 1.13724624 0.996214946 0.642331695 0.969555418 1 11.97428017 -4.27907285 3.506164676 1.065332444 0.599057703 0.740441259 0.079072933 0.129187398 2.776085284 0.013004619 0.154776546 5.26E-05 4.27907285 -0.466274741 GPRIS(ph)APNVDFNLEGPK ddPTM_HeLa_Curcumin_4h_R1 2 GPRISAPNVDFNLEGPK 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GPRIS(1)APNVDFNLEGPK;GPRIS(1)APNVDFNLEGPK ; 160.47 0.00077555 154158000 5851.9 4788.5 3966.81 5173.63 4578.29 9112.8 8042.5 3978.08 8395.6 6425.5 TRUE FALSE FALSE 5388.71594 5202.396603 4113.823468 5152.22289 4523.696882 7222.702558 8268.150905 5190.978279 7474.623685 6648.785647 0.810481226 0.782458163 0.618733057 0.774911866 0.680379414 1.086319058 1.243558049 0.780740808 1.124208853 1 12.69887515 -5.230713302 24.50399006 0.852581001 1.057541241 0.221103074 0.174534616 622.0112484 496051.5652 0.02382356 0.060730111 5.88E-06 5.230713302 0.20496024 GPRT(ph)PS(ph)PPPPIPEDIALGK ddPTM_HeLa_Curcumin_4h_R1 1 GPRTPSPPPPIPEDIALGK 19 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 2 0 GPRT(1)PS(1)PPPPIPEDIALGK 107.07 0.00093972 9235900 5652.9 4329.8 5231.3 5156.5 5192.8 5163.6 4855.6 3909.7 5697.7 4410.9 TRUE FALSE FALSE 5205.467 4704.048619 5425.17658 5135.163769 5130.879252 4092.611154 4991.835068 5101.749532 5072.676565 4564.178447 1.140504707 1.030645202 1.188642522 1.125101446 1.124162719 0.896680794 1.093698488 1.117780471 1.111410657 1 12.15613948 -4.527298294 24.97709542 1.07040887 1.111760054 0.018619004 0.079505202 346.6696461 1959229.318 0.011817812 0.044603246 2.97E-05 4.527298294 0.041351184 AGSST(ph)PGDAPPAVAEVQGR ddPTM_HeLa_Curcumin_4h_R1 3 AGSSTPGDAPPAVAEVQGR 19 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 AGS(0.005)S(0.039)T(0.956)PGDAPPAVAEVQGR;AGS(0.037)S(0.151)T(0.812)PGDAPPAVAEVQGR;AGS(0.007)S(0.078)T(0.915)PGDAPPAVAEVQGR ;; 297.55 2.10E-83 134335000 6998.09 6089.98 6484.46 6265.74 6543.83 8327.95 6834.14 13156.8 8243.5 6488.42 TRUE FALSE FALSE 6444.183792 6616.370735 6724.779792 6239.814028 6465.799101 6600.639295 7025.887575 17168.24775 7339.208674 6713.892112 0.959828321 0.985474688 1.001621664 0.929388486 0.963047811 0.98313157 1.046470134 2.557122972 1.093137714 1 12.71293364 -4.260836546 5.118307332 0.978565042 2.630196192 0.992223153 0.04148631 0.005405577 0.460632573 0.003316217 0.031382237 5.48E-05 4.260836546 1.65163115 up GPS(ph)PAPASS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 GPSPAPASSPK 11 0 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 2 0 GPS(1)PAPAS(0.404)S(0.596)PK;GPS(1)PAPAS(0.083)S(0.917)PK ; 120.6 0.0098357 94343200 17871.2 17162.3 18918.1 17484 20489.4 17805.3 15956.9 6488.5 15922.8 14481.9 TRUE FALSE FALSE 16456.67566 18645.73274 19619.22143 17411.65584 20245.07729 14112.28007 16404.60767 8466.813781 14176.10868 14985.14495 1.098199298 1.244281107 1.309244688 1.161927756 1.351009774 0.941751323 1.094724657 0.565013806 0.946010781 1 13.87124542 -4.259160793 5.991421435 1.101891482 0.549888413 0.595611039 0.137592109 0.079094657 13.37376333 0.019710802 0.175397473 5.51E-05 4.259160793 -0.552003069 GPS(ph)PAPASS(ph)PKR ddPTM_HeLa_Curcumin_4h_R1 2 GPSPAPASSPKR 12 1 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 2 0 GPS(1)PAPAS(0.054)S(0.946)PKR;GPS(0.97)PAPAS(0.06)S(0.969)PKR ; 95.195 0.0055766 90832000 12184.7 11492.1 12903.9 11784.6 14097.6 13454.1 10922.7 4426.5 11556.5 10551.4 TRUE FALSE FALSE 11220.26814 12485.42592 13382.12989 11735.83845 13929.49533 10663.568 11229.16157 5776.119473 10288.78086 10918.06036 1.027679621 1.143557143 1.225687479 1.074901407 1.275821425 0.976690698 1.028494182 0.529042639 0.942363434 1 13.41442896 -4.248576474 3.896613068 1.057857035 0.471485838 0.713229419 0.1037628 0.119002822 3.51843515 0.014782483 0.20050777 5.64E-05 4.248576474 -0.586371197 GPS(ph)PEGSSSTESSPEHPPK ddPTM_HeLa_Curcumin_4h_R1 1 GPSPEGSSSTESSPEHPPK 19 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 GPS(0.418)PEGS(0.124)S(0.124)S(0.124)T(0.124)ES(0.043)S(0.043)PEHPPK 72.585 0.00336 0 2101 1620.8 1692.8 1386.9 2839.6 3774.4 1621 784.01 2442 1561.7 TRUE FALSE FALSE 1934.703633 1760.89473 1755.536657 1381.161375 2805.739625 2991.546894 1666.480897 1023.05104 2174.11871 1615.968959 1.197240592 1.089683512 1.086367809 0.854695486 1.736258366 1.851240321 1.031257988 0.633088299 1.345396332 1 10.65818377 -5.792643764 24.99975578 1.079554697 1.33128928 0.087459696 0.339619578 339.5394963 272025.1477 0.050281031 0.091148489 1.61E-06 5.792643764 0.251734583 GPS(ph)PSPVGSPASVAQSR ddPTM_HeLa_Curcumin_4h_R1 4 GPSPSPVGSPASVAQSR 17 0 O14497;O14497-2;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497 ARID1A AT-rich interactive domain-containing protein 1A 1 0 GPS(0.799)PS(0.2)PVGS(0.002)PASVAQSR;GPS(1)PSPVGSPASVAQSR;GPS(0.968)PS(0.032)PVGSPASVAQSR;GPS(0.962)PS(0.038)PVGSPASVAQSR ;;; 249.89 2.85E-40 261691000 6319.3 6114.5 5950.9 6524.4 6855.5 7313.1 5905.2 3057.11 6462.4 6328 TRUE FALSE FALSE 5819.120737 6643.010134 6171.445589 6497.403762 6773.75264 5796.280624 6070.884019 3989.208766 5753.490888 6547.897529 0.888700642 1.014525671 0.942507967 0.992288553 1.034492768 0.885212482 0.927150126 0.609235063 0.8786776 1 12.67681603 -3.965917163 1.752813828 0.95778718 0.204854763 0.784436266 0.05387051 0.802928114 1.252500779 0.007849193 1.290589685 0.000108164 3.965917163 -0.752932417 GPS(ph)PSS(ph)PTPPAAAAPAEQAPR ddPTM_HeLa_Curcumin_4h_R1 2 GPSPSSPTPPAAAAPAEQAPR 21 0 Q86VQ1 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 2 0 GPS(1)PS(0.001)S(0.941)PT(0.058)PPAAAAPAEQAPR;GPS(0.956)PS(0.044)S(0.999)PT(0.001)PPAAAAPAEQAPR ; 181.64 1.47E-09 79429000 3332.55 3610.05 3446.98 3482.45 3815.1 3759.9 2199.09 1465.88 4381.29 3873.6 TRUE FALSE FALSE 3068.775151 3922.086636 3574.728111 3468.040545 3769.607424 2980.054357 2260.790547 1912.820064 3900.673448 4008.207312 0.765622861 0.978513917 0.891852101 0.865234823 0.940472169 0.74348808 0.564040323 0.477225831 0.973171581 1 11.96874141 -4.847504778 2.099124031 0.895337478 0.486224051 0.844206743 0.067739173 0.126105248 1.058360299 0.012888548 0.062511963 1.42E-05 4.847504778 -0.409113427 GPS(ph)SVEDIK ddPTM_HeLa_Curcumin_4h_R1 2 GPSSVEDIK 9 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 0 GPS(0.5)S(0.5)VEDIK;GPS(0.5)S(0.5)VEDIK ; 126.03 0.0046748 82056000 9756.8 9393.3 9257.7 9868.9 11379.4 12139 10210.8 8880.3 10282 8455.6 TRUE FALSE FALSE 8984.538985 10205.215 9600.798506 9828.065107 11243.70809 9621.234565 10497.28757 11587.86259 9154.090324 8749.431471 1.026871176 1.166386071 1.097305412 1.123280426 1.285078708 1.099641114 1.199767962 1.324413207 1.046249731 1 13.09497356 -5.85018059 0.310348466 0.981999701 1.329038492 0.614274405 0.063381457 1.218064972 0.187604864 0.035307981 0.15130222 1.41E-06 5.85018059 0.347038791 GPS(ph)TPNVK ddPTM_HeLa_Curcumin_4h_R1 1 GPSTPNVK 8 0 Q9Y4E8-2;Q9Y4E8-3 Q9Y4E8-2 USP15 Ubiquitin carboxyl-terminal hydrolase 15 1 0 GPS(0.556)T(0.444)PNVK 99.013 0.01563 42343000 10184 9273.5 9962.3 9990.5 10291 12808 8706.4 8967.3 12269 9854.4 TRUE FALSE FALSE 9377.925654 10075.06002 10331.5116 9949.161958 10168.28655 10151.47642 8950.678152 11701.38849 10923.1214 10196.83967 0.919689429 0.988057118 1.013207223 0.975710346 0.997199807 0.995551245 0.877789437 1.147550503 1.07122616 1 13.31583446 -7.026167743 23.35308586 0.961643862 0.994522545 0 0.072797709 778.7400086 694976.7189 0.010284441 0.012626551 9.42E-08 7.026167743 0.032878683 GPS(ph)TPYTK ddPTM_HeLa_Curcumin_4h_R1 1 GPSTPYTK 8 0 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 0 GPS(0.901)T(0.091)PYT(0.008)K 93.598 0.0188 17962000 10618 12035 8907.2 11521 10199 14536 12212 4840 14978 10298 TRUE FALSE FALSE 9777.574096 13075.25177 9237.308668 11473.32915 10077.38359 11521.06975 12554.63585 6315.693719 13334.95087 10655.85473 0.917577645 1.227048613 0.86687637 1.076715988 0.945713304 1.081196209 1.178191348 0.592697055 1.251420107 1 13.3793587 -4.24444501 24.5745944 0.997352891 0.592696646 0.45956322 0.137623731 1602.461345 2317183.453 0.014942284 0.561064906 5.70E-05 4.24444501 -0.404656245 NNSFT(ph)APSTVGK ddPTM_HeLa_Curcumin_4h_R1 1 NNSFTAPSTVGK 12 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 0 NNS(0.102)FT(0.896)APS(0.002)TVGK 158.31 0.00077176 18134000 3166 2434.4 3430.6 3054.4 3339 3189.7 4022.5 20881 2585.7 2415.5 TRUE FALSE FALSE 2915.407759 2644.818689 3557.741054 3041.761702 3299.184606 2528.120265 4135.360524 27247.52078 2302.055179 2499.438445 1.166425108 1.058165162 1.423416152 1.216978041 1.319970337 1.011475305 1.65451585 10.90145702 0.921028955 1 11.28738828 -4.260816756 4.78182265 1.1316924 11.45503587 0.997513414 0.145558706 0.00600082 0.387719153 0.020686493 0.205640197 5.49E-05 4.260816756 10.32334347 up NPS(ph)SSVPPPSAGSVK ddPTM_HeLa_Curcumin_4h_R1 2 NPSSSVPPPSAGSVK 15 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 NPS(0.938)S(0.06)S(0.002)VPPPSAGSVK;NPS(0.497)S(0.497)S(0.005)VPPPSAGSVK ; 133.28 0.00066142 23852400 2798 1682.18 3548.4 4219.2 3022.8 3426.2 5303.1 41737 0 2991.5 TRUE FALSE FALSE 2576.535348 1827.580144 3679.906825 4201.742068 2986.755084 2715.567499 5451.890713 54462.41917 0 3095.454402 0.832360944 0.59040771 1.188809896 1.357391039 0.964884213 0.877275885 1.761256993 17.59432125 0 1 11.59593549 -4.260807841 4.935113081 0.956103461 18.45434734 0.994868424 0.359026774 0.004913824 0.360394386 0.030179172 0.293015943 5.49E-05 4.260807841 17.49824388 up GPSASDK(ac)PSQETLTR ddPTM_HeLa_Curcumin_4h_R1 1 GPSASDKPSQETLTR 15 1 Q9BVI0;Q5JWZ0;Q5JXL1 Q9BVI0 PHF20 PHD finger protein 20 0 1 GPSASDK(1)PSQETLTR 82.543 0.0067114 0 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 SVS(ph)KESVASMGADSGDDFASDGSSSR ddPTM_HeLa_Curcumin_4h_R1 2 SVSKESVASMGADSGDDFASDGSSSR 26 1 Q5T165;Q92805 Q5T165 GOLGA1 Golgin subfamily A member 1 1 0 S(0.2)VS(0.484)KES(0.257)VAS(0.052)MGADS(0.006)GDDFASDGSSSR;S(0.032)VS(0.719)KES(0.162)VAS(0.087)MGADSGDDFASDGSSSR ; 65.06 0.0032638 30491000 3067.5 3078.3 2890.3 2777 3277.8 4030.3 2952.4 8483.7 3310.1 2385.3 TRUE FALSE FALSE 2824.704138 3344.374535 2997.417061 2765.50951 3238.714376 3194.370349 3035.236398 11070.34108 2946.990311 2468.188997 1.14444402 1.354991266 1.214419586 1.120460999 1.312182486 1.294216266 1.229742293 4.485208016 1.193988918 1 11.26923716 -4.260806589 5.763865876 1.137653253 4.590448993 0.986624495 0.114294882 0.012990808 1.855531963 0.019802393 0.175137038 5.49E-05 4.260806589 3.452795741 up GPSPAAAS(ph)PEGSPLR ddPTM_HeLa_Curcumin_4h_R1 2 GPSPAAASPEGSPLR 15 0 Q9P107;Q9P107-2 Q9P107 GMIP GEM-interacting protein 1 0 GPS(0.001)PAAAS(0.997)PEGS(0.002)PLR;GPSPAAAS(1)PEGSPLR ; 153.2 0.00040729 26296000 2620.3 1970.51 2438.68 2547.79 2591.54 3209.9 2387.7 1527.68 2414.7 2585.6 TRUE FALSE FALSE 2412.90049 2140.832104 2529.059626 2537.24792 2560.637578 2544.130557 2454.692436 1993.462599 2149.813451 2675.449408 0.901867359 0.800176635 0.94528404 0.948344571 0.957086899 0.950917087 0.917487892 0.745094485 0.803533584 1 11.38556553 -9.024803669 0.886940859 0.99839268 0.901649103 0 0.09012529 0.673997195 0.988623448 0.040114375 0.013182149 9.44E-10 9.024803669 -0.096743577 SQS(ph)ADAPGPTER ddPTM_HeLa_Curcumin_4h_R1 1 SQSADAPGPTER 12 0 M0R1B8;M0R2U7;Q9NSC5-5;Q9NSC5-2;Q9NSC5 M0R1B8 HOMER3 Homer protein homolog 3 1 0 S(0.011)QS(0.989)ADAPGPTER 133.23 0.0020554 19356000 1570 1032.4 1365.5 1625 1368.4 1804.8 2705.7 25019 0 1225 TRUE FALSE FALSE 1445.732843 1121.636056 1416.106631 1618.276181 1352.082724 1430.464136 2781.61466 32647.17793 0 1267.568659 1.140555845 0.884872033 1.117183374 1.276677338 1.066674152 1.12851018 2.194448909 25.75574719 0 1 10.30784818 -4.260803722 5.055018633 1.091986584 26.94218819 0.997660457 0.358733264 0.00238925 0.193342742 0.022499312 0.214797215 5.49E-05 4.260803722 25.85020161 up TGMTNMT(ph)QSLERMKQS(ph)WK ddPTM_HeLa_Curcumin_4h_R1 1 TGMTNMTQSLERMKQSWK 18 2 O14756 O14756 HSD17B6 17-beta-hydroxysteroid dehydrogenase type 6 2 0 T(0.007)GMT(0.072)NMT(0.859)QS(0.062)LERMKQS(0.998)WK 53.777 0.018443 7732000 1730.5 1388.3 1338.4 1401.4 1394.4 2094.4 1778.8 4069 2118.1 1851.9 TRUE FALSE FALSE 1593.529099 1508.298466 1388.002281 1395.601378 1377.772691 1659.997831 1828.708341 5309.619369 1885.749729 1916.253387 0.831585796 0.787108049 0.724331287 0.728296888 0.718992958 0.866272614 0.954314473 2.770833651 0.984081616 1 10.90407263 -4.26076749 4.986160694 0.865508617 2.866400262 0.971061483 0.099848799 0.023925249 1.829825665 0.017066239 0.164561418 5.49E-05 4.26076749 2.000891645 up QGPSPVS(ph)PNALDR ddPTM_HeLa_Curcumin_4h_R1 2 QGPSPVSPNALDR 13 0 H0Y3A3;A0A3B3ITG3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-2;Q5VWQ8-5;Q5VWQ8 H0Y3A3 DAB2IP Disabled homolog 2-interacting protein 1 0 QGPS(0.008)PVS(0.992)PNALDR;QGPS(0.07)PVS(0.93)PNALDR ; 154.81 0.0004 77545000 1993.72 1578.83 1672.96 1534.45 1532.64 2351.5 1869.49 3394.5 2020.71 1889.44 TRUE FALSE FALSE 1835.914958 1715.29703 1734.961369 1528.100852 1514.364269 1863.772393 1921.942858 4429.467424 1799.043169 1955.097899 0.939039911 0.877345851 0.887403833 0.781598125 0.774572092 0.953288525 0.983041749 2.265598784 0.920180605 1 10.93302514 -4.260723255 5.230157754 0.930473528 2.323484024 0.967153908 0.075292983 0.023729299 2.213787911 0.012667817 0.11837655 5.49E-05 4.260723255 1.393010496 up S(ph)SDEENGPPSS(ph)PDLDR ddPTM_HeLa_Curcumin_4h_R1 2 SSDEENGPPSSPDLDR 16 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 2 0 S(0.999)S(0.001)DEENGPPSS(1)PDLDR;S(0.774)S(0.226)DEENGPPS(0.014)S(0.986)PDLDR ; 351.47 5.16E-172 147455000 5138.5 4427 4635.7 4221.1 4434 5582.8 4293.3 6076.6 4931.9 3508.9 TRUE FALSE FALSE 4731.782303 4809.650154 4807.50312 4203.634207 4381.127446 4424.864349 4413.758443 7929.327367 4390.882909 3630.834014 1.303221873 1.324668144 1.32407681 1.15775995 1.206644928 1.218690894 1.215632118 2.183885944 1.209331766 1 11.82608526 -4.260690946 5.478122859 1.182588595 2.221317252 0.90088033 0.095559867 0.04388154 4.996026438 0.018691453 0.170003538 5.49E-05 4.260690946 1.038728657 up GPSPSS(ph)PTPPAAAAPAEQAPR ddPTM_HeLa_Curcumin_4h_R1 2 GPSPSSPTPPAAAAPAEQAPR 21 0 Q86VQ1 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 0 GPS(0.041)PS(0.007)S(0.868)PT(0.084)PPAAAAPAEQAPR;GPS(0.327)PS(0.197)S(0.473)PT(0.003)PPAAAAPAEQAPR ; 266.99 1.40E-59 83855000 3084.9 2320.2 2750.7 3037.3 2650.8 3311.1 2985.9 3372.4 3368.6 2685.2 TRUE FALSE FALSE 2840.72691 2520.747749 2852.643362 3024.732457 2619.190941 2624.340536 3069.676318 4400.629235 2999.073008 2778.5105 1.022392001 0.907229881 1.026680792 1.088616529 0.942660084 0.944513449 1.104792052 1.583808748 1.079381563 1 11.44009598 -4.274206771 3.131316004 1.001932612 1.663232322 0.907476232 0.055519132 0.060832255 0.920473898 0.006783635 0.096968106 5.32E-05 4.274206771 0.66129971 GPSQATS(ph)PIR ddPTM_HeLa_Curcumin_4h_R1 1 GPSQATSPIR 10 0 Q7RTP6;J3QR21;J3QLA3 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 0 GPSQAT(0.118)S(0.882)PIR 92.943 0.01726 38121000 6035.7 5309.6 5650.7 5193.2 6622.4 6427.2 5542.9 4766.4 6110.7 4849 TRUE FALSE FALSE 5557.967976 5768.538165 5860.119913 5171.711914 6543.432205 5094.126271 5698.418856 6219.653418 5440.371498 5017.502389 1.10771606 1.149683192 1.16793565 1.03073432 1.304121393 1.015271319 1.13570825 1.239591521 1.084278806 1 12.29275368 -8.905182418 0.362246253 0.960382274 1.158424856 0.17031143 0.084602868 1.899810244 0.40298992 0.150967369 0.03414147 1.24E-09 8.905182418 0.198042582 GPSQEEEDNHS(ph)DEEDR ddPTM_HeLa_Curcumin_4h_R1 2 GPSQEEEDNHSDEEDR 16 0 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 0 GPSQEEEDNHS(1)DEEDR;GPSQEEEDNHS(1)DEEDR ; 137.99 0.00019358 1746100 839.24 597.41 685.79 641.3 900.66 642.88 581.53 462.97 403.15 528.65 TRUE FALSE FALSE 772.8132684 649.0474584 711.2059807 638.6464705 889.9202177 509.5394412 597.8461667 604.1274217 358.9254536 547.0205482 1.412768261 1.186513853 1.300144909 1.167499964 1.626849706 0.931481355 1.092913545 1.104396213 0.656146199 1 9.095451217 GPSQEEEDNHSDEEDRAS(ph)EPK ddPTM_HeLa_Curcumin_4h_R1 1 GPSQEEEDNHSDEEDRASEPK 21 1 E7ERS3;Q86VM9;H3BPD0 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 0 GPS(0.001)QEEEDNHS(0.072)DEEDRAS(0.928)EPK 87.356 0.00029837 8141600 1731.1 1677.4 1699.3 1579.5 1558.6 2022.3 1713 2266.7 1723.1 1674.1 TRUE FALSE FALSE 1594.081608 1822.386982 1762.277553 1572.964448 1540.014713 1602.852184 1761.06217 2957.806395 1534.080241 1732.27485 0.920224414 1.052019534 1.017319828 0.908033992 0.889012914 0.925287453 1.016618217 1.707469455 0.885587088 1 10.75845214 -4.261623802 4.324509066 0.960960822 1.762600961 0.945072646 0.054424707 0.032968841 1.449220942 0.007527895 0.080925182 5.47E-05 4.261623802 0.801640139 GPSS(ph)VEDIK ddPTM_HeLa_Curcumin_4h_R1 1 GPSSVEDIK 9 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 0 GPS(0.209)S(0.791)VEDIK 135.8 0.0030082 195870000 4911.3 4955.2 5316.2 4902.2 5589.2 6339.2 6125.5 3991.8 4805.3 4466.6 TRUE FALSE FALSE 4522.565423 5383.505408 5513.223049 4881.915995 5522.55244 5024.378462 6297.365044 5208.881444 4278.170612 4621.814018 0.978526052 1.164803557 1.192869948 1.056277033 1.194888505 1.087100962 1.362531037 1.127020997 0.925647505 1 12.17424349 -7.257441993 21.2545346 0.989859512 1.171159422 0.5655161 0.080165053 22.56665338 119987.9322 0.012252326 0.014684033 5.53E-08 7.257441993 0.18129991 GPSSVEDIK ddPTM_HeLa_Curcumin_4h_R1 1 GPSSVEDIK 9 0 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 0 0 106.68 0.0047041 41595000 6484.2 4924.7 5183.3 5523.1 5243.9 6060 5026.7 4877.8 6040.4 4996.4 FALSE FALSE TRUE 5970.968728 5350.369124 5375.397658 5500.246876 5181.369917 4803.08769 5167.735673 6365.018765 5377.783232 5170.024528 1.154920774 1.034882735 1.039723821 1.063872491 1.002194456 0.929026093 0.999557284 1.231138988 1.040185245 1 12.33595541 GPSSVEDIK(ac)AK ddPTM_HeLa_Curcumin_4h_R1 1 GPSSVEDIKAK 11 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 0 1 GPSSVEDIK(1)AK 117.14 0.0024337 3467300 1920.1 1773.1 1657.6 1685.8 1731.8 2814.4 2300.5 2839.4 3230.3 1696.3 FALSE TRUE FALSE 1768.122059 1926.358863 1719.032114 1678.824606 1711.149416 2230.661715 2365.045839 3705.119989 2875.944172 1755.246299 1.007335586 1.097486355 0.979368033 0.956460986 0.974877097 1.270853963 1.347415369 2.110883237 1.638484681 1 10.77745777 -3.543156681 0.953716645 1.002888761 5.131011369 0.654169428 0.210424026 0.754092409 0.196015204 0.009115429 4.474462018 0.000286314 3.543156681 4.128122608 GPSTPKSPGASNFS(ph)TLPK ddPTM_HeLa_Curcumin_4h_R1 1 GPSTPKSPGASNFSTLPK 18 1 Q9Y4E8 Q9Y4E8 USP15 Ubiquitin carboxyl-terminal hydrolase 15 1 0 GPS(0.003)T(0.007)PKS(0.268)PGAS(0.085)NFS(0.487)T(0.15)LPK 55.337 0.016226 94427000 1354.6 795.63 846.13 963.48 572.76 918.73 842.86 1394.4 1295.4 940.99 TRUE FALSE FALSE 1247.381981 864.4007119 877.4883221 959.493375 565.9302111 728.1750418 866.5083832 1819.546141 1153.297861 973.6893325 1.281088268 0.887758223 0.901199482 0.985420445 0.581222565 0.747851514 0.889922847 1.868713234 1.184461843 1 9.927317726 -7.242933648 24.06419001 1.132736136 0.94968776 0.049670029 0.327788067 1166.7687 1517224.632 0.054408101 0.066560378 5.72E-08 7.242933648 -0.183048376 GPSWDPFRDWYPHSR ddPTM_HeLa_Curcumin_4h_R1 2 GPSWDPFRDWYPHSR 15 1 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 0 0 ; ; 101.45 0.0015996 146649000 15334.7 10899.2 11319 11798 11889.6 31581 14858.6 11064.9 15859.9 11286.7 FALSE FALSE TRUE 14120.94231 11841.27828 11738.4921 11749.183 11747.82429 25030.74461 15275.49233 14438.53707 14120.10865 11678.91198 1.209097417 1.013902519 1.005101512 1.006016915 1.005900575 2.14324285 1.307955086 1.236291282 1.209026035 1 13.51161826 GPTPAT(ph)PESFSK ddPTM_HeLa_Curcumin_4h_R1 1 GPTPATPESFSK 12 0 P49454 P49454 CENPF Centromere protein F 1 0 GPT(0.331)PAT(0.522)PES(0.147)FSK 120.84 0.010088 8217900 2313.7 1948.6 2271.1 2346 2589.5 3258 3119.8 1113.1 2555.3 2036.3 TRUE FALSE FALSE 2130.568204 2117.028301 2355.268964 2336.292874 2558.621904 2582.254075 3207.333191 1452.479066 2274.989983 2107.061273 1.011156263 1.004730298 1.117798041 1.10879209 1.214308258 1.22552396 1.522183162 0.689338789 1.079698067 1 11.04101655 -6.447376975 1.483541263 1.004121895 1.188416645 0.075898219 0.193078098 0.512076696 2.235002377 0.029247411 0.049792948 3.57E-07 6.447376975 0.184294749 GPTSTSIDNIDGT(ph)PVRDER ddPTM_HeLa_Curcumin_4h_R1 4 GPTSTSIDNIDGTPVRDER 19 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 GPTSTSIDNIDGT(1)PVRDER;GPTSTSIDNIDGT(1)PVRDER;GPTSTSIDNIDGT(1)PVRDER;GPTSTSIDNIDGT(1)PVRDER ;;; 258.68 8.31E-43 137964000 9582.8 7365.1 8122.9 8043.8 7780.8 9416 7856.3 6588.7 9434 6668.4 TRUE FALSE FALSE 8824.311268 8001.706426 8423.94182 8010.516887 7688.019042 7463.01546 8076.726634 8597.564299 8399.113803 6900.126404 1.278862263 1.159646354 1.220838768 1.160923209 1.114185247 1.08157663 1.170518649 1.246000986 1.217240571 1 12.75240708 -9.532912651 1.299530958 1.000229747 1.186190995 0 0.08629076 0.277586997 0.841141792 0.045230734 0.010854156 2.93E-10 9.532912651 0.185961249 GPTTGEGALDLSDVHS(ph)PPKS(ph)PEGK ddPTM_HeLa_Curcumin_4h_R1 2 GPTTGEGALDLSDVHSPPKSPEGK 24 1 O95684;O95684-2 O95684 FGFR1OP FGFR1 oncogene partner 2 0 GPTTGEGALDLS(0.067)DVHS(0.943)PPKS(0.99)PEGK;GPT(0.001)T(0.001)GEGALDLS(0.125)DVHS(0.903)PPKS(0.97)PEGK ; 65.438 0.00075891 48230300 5413.6 4962.1 5180.1 5111.6 6167.5 6420.9 5306.8 6391.2 6532.4 5586.3 TRUE FALSE FALSE 4985.107848 5391.001813 5372.079063 5090.449554 6093.956591 5089.132962 5455.694525 8339.847459 5815.812063 5780.423509 0.862412216 0.93263094 0.929357348 0.880636089 1.054240503 0.880408322 0.943822631 1.442774469 1.006122139 1 12.49695948 -4.261766041 6.792366842 0.934106075 1.451245383 0.865231155 0.059050562 0.029682907 9.434243428 0.008593097 0.070331655 5.47E-05 4.261766041 0.517139307 GPTTGEGALDLSDVHS(ph)PPKSPEGK ddPTM_HeLa_Curcumin_4h_R1 2 GPTTGEGALDLSDVHSPPKSPEGK 24 1 O95684;O95684-2 O95684 FGFR1OP FGFR1 oncogene partner 1 0 GPTTGEGALDLS(0.022)DVHS(0.779)PPKS(0.199)PEGK;GPTTGEGALDLS(0.062)DVHS(0.786)PPKS(0.151)PEGK ; 102.07 2.98E-06 27595000 7820.4 7589.4 7019.8 7190.3 8478.2 7238 6538.5 7367.4 8493.2 7799.9 TRUE FALSE FALSE 7201.407088 8245.393918 7279.959963 7160.548444 8377.103002 5736.757211 6721.952713 9613.686345 7561.517209 8070.945944 0.89226308 1.021614316 0.901995877 0.887200645 1.037933231 0.710791182 0.832858101 1.191147408 0.936881161 1 12.97852206 GPVEGYEENEEFLR ddPTM_HeLa_Curcumin_4h_R1 2 GPVEGYEENEEFLR 14 0 F5GYQ2;Q9UI30-2;Q9UI30;F5GX77 F5GYQ2 TRMT112 Multifunctional methyltransferase subunit TRM112-like protein 0 0 ; ; 202 5.18E-08 50291000 2682.14 1902.42 2144.19 1874.33 2239.83 3846.7 2370.88 2123.98 2287.63 1973.42 FALSE FALSE TRUE 2469.845789 2066.856708 2223.655568 1866.574519 2213.12149 3048.851059 2437.400512 2771.571724 2036.682712 2041.996198 1.209525165 1.012174611 1.088961659 0.914093043 1.083802944 1.493073817 1.193636166 1.357285448 0.997397896 1 10.99576446 -5.292167868 22.04305728 1.078534128 1.332562138 0.633502628 0.103521 91.30319436 65496.19233 0.016148518 0.036117505 5.10E-06 5.292167868 0.25402801 GPVGTVS(ph)EAQLAR ddPTM_HeLa_Curcumin_4h_R1 1 GPVGTVSEAQLAR 13 0 Q9NZM1-8;Q9NZM1-7;Q9NZM1-5;Q9NZM1-2;Q9NZM1-6;Q9NZM1-3;Q9NZM1 Q9NZM1-8 MYOF Myoferlin 1 0 GPVGT(0.046)VS(0.954)EAQLAR 98.582 0.0084682 0 2585.8 2158.9 2789.5 2717.3 2268.5 3006.5 2573.1 2240.9 2536.3 2296 TRUE FALSE FALSE 2381.131201 2345.505696 2892.881324 2706.056533 2241.449619 2382.91801 2645.294261 2924.140094 2258.074236 2375.785829 1.002249939 0.987254687 1.217652403 1.139015352 0.943456094 1.00300203 1.1134397 1.230809637 0.950453617 1 11.21418907 -4.448606209 2.697851068 1.021552088 1.236357912 0.364261131 0.081379477 0.265566222 3.177233956 0.0116368 0.103403897 3.56E-05 4.448606209 0.214805824 GPVSGS(ph)PDSMNASR ddPTM_HeLa_Curcumin_4h_R1 3 GPVSGSPDSMNASR 14 0 A0A499FJS7;O14920-4;O14920-2;O14920 A0A499FJS7 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 1 0 GPVS(0.001)GS(0.513)PDS(0.478)MNAS(0.009)R;GPVSGS(0.652)PDS(0.341)MNAS(0.007)R;GPVS(0.003)GS(0.641)PDS(0.356)MNASR ;; 209.22 2.07E-09 59437000 10179 8446.3 8898.7 8952.4 9548.8 10445.4 7884.8 7224.6 8686 7974.3 TRUE FALSE FALSE 9373.321409 9176.360536 9228.49365 8915.357341 9434.936797 8278.906296 8106.026267 9427.347282 7733.167531 8251.406331 1.135966529 1.112096553 1.118414641 1.080465194 1.143433788 1.003332761 0.982381177 1.142514003 0.937193882 1 13.01042431 -3.930263748 19.64128663 1.070167855 2.83748217 0.093561396 0.069762599 443.0923557 152357.7765 0.009114677 7500.921241 0.000117418 3.930263748 1.767314315 GPVSGSPDS(ph)MNASR ddPTM_HeLa_Curcumin_4h_R1 1 GPVSGSPDSMNASR 14 0 A0A499FJS7;O14920-4;O14920-2;O14920 A0A499FJS7 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta 1 0 GPVSGS(0.32)PDS(0.679)MNASR 117.48 0.0023317 13216000 4689.9 3619.6 4026 3981.3 4261.5 4081.9 3691.3 3310 3752.8 3451.2 TRUE FALSE FALSE 4318.689466 3932.462095 4175.207102 3964.826436 4210.684396 3235.267928 3794.867943 4319.203763 3341.127229 3571.128943 1.209334509 1.101181771 1.169156076 1.110244547 1.179090552 0.905951025 1.062652176 1.209478524 0.935594117 1 11.80216451 -4.249523039 22.96733089 1.09697456 1.209478743 0.108384341 0.098938108 1089.461478 2099679.918 0.013801952 0.274326299 5.63E-05 4.249523039 0.112504182 NPQNSSQS(ph)ADGLR ddPTM_HeLa_Curcumin_4h_R1 2 NPQNSSQSADGLR 13 0 P0DN76;Q01081 P0DN76 U2AF1 Splicing factor U2AF 35 kDa subunit 1 0 NPQNS(0.008)S(0.003)QS(0.989)ADGLR;NPQNS(0.07)S(0.222)QS(0.709)ADGLR ; 160.63 0.00025677 13903400 2253.31 1938.04 1747.03 1865.07 1907.69 2809.69 2089.13 4065.3 2190.97 2036.81 TRUE FALSE FALSE 2074.958136 2105.555542 1811.776469 1857.352835 1884.942043 2226.928622 2147.745365 5304.791256 1950.626073 2107.588996 0.984517446 0.999035175 0.859644111 0.881268994 0.894359406 1.056623766 1.019053226 2.516995138 0.92552489 1 11.04137784 -4.260644542 5.634560063 0.97391564 2.569551688 0.982662684 0.062127419 0.013334615 1.718922181 0.009076717 0.081369021 5.49E-05 4.260644542 1.595636048 up GQAAVQQLQAEGLSPR ddPTM_HeLa_Curcumin_4h_R1 1 GQAAVQQLQAEGLSPR 16 0 P16152;E9PQ63;A8MTM1;P16152-2;O75828 P16152 CBR1;CBR3 Carbonyl reductase [NADPH] 1;Carbonyl reductase [NADPH] 3 0 0 237.21 3.17E-37 2885000 582.68 578.01 463.28 517.19 668.82 780.95 652.18 475.26 750 517.45 FALSE FALSE TRUE 536.5602632 627.9706088 480.4495643 515.0500048 660.8447583 618.9721669 670.4784155 620.1645862 667.7268764 535.431349 1.00210842 1.172831232 0.897313101 0.96193472 1.234228738 1.156025265 1.252221068 1.15825229 1.247082147 1 9.0645578 -5.759875486 24.99999741 1.004256934 1.200744909 0.296032699 0.104023426 18.70455573 298996.8748 0.00976867 0.018738781 1.74E-06 5.759875486 0.196487975 GQDGIGSK(ac)AEK ddPTM_HeLa_Curcumin_4h_R1 1 GQDGIGSKAEK 11 1 P09874 P09874 PARP1 Poly [ADP-ribose] polymerase 1 0 1 GQDGIGSK(1)AEK 103.75 0.0065522 4093700 3385.9 2745.8 2624.9 2940.2 2793 3836.8 2768.3 2188.9 3139.7 2358.9 FALSE TRUE FALSE 3117.902442 2983.134717 2722.181103 2928.034231 2759.695299 3041.00443 2845.971048 2856.285534 2795.282765 2440.871599 1.277372576 1.222159624 1.115249612 1.199585522 1.130618792 1.245868251 1.165965079 1.170190818 1.145198611 1 11.25318069 -9.469528211 1.198222438 0.999624977 1.19765731 0.255145511 0.063937623 0.224686797 0.57538678 0.036686433 0.008961894 3.39E-10 9.469528211 0.198032333 GQDVVQEWQETSPT(ph)REEPAGEQK ddPTM_HeLa_Curcumin_4h_R1 1 GQDVVQEWQETSPTREEPAGEQK 23 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 GQDVVQEWQET(0.068)S(0.184)PT(0.748)REEPAGEQK 71.202 0.0012821 34849000 3094.8 2642.2 3219.6 2818.8 2852.2 3295 3049.3 3414.9 3030.6 2872.2 TRUE FALSE FALSE 2849.843314 2870.579995 3338.921208 2807.136552 2818.189378 2611.579858 3134.855151 4456.08729 2698.150762 2972.008736 0.958894663 0.965871991 1.123456054 0.944525 0.948243975 0.878725498 1.054793384 1.499352016 0.90785425 1 11.53722264 -4.275700695 3.691685942 0.978628682 1.548216447 0.864471663 0.062850818 0.059615254 1.510976165 0.00796047 0.090734062 5.30E-05 4.275700695 0.569587764 GQEADLEAGGEEVPEANGS(ph)AGKR ddPTM_HeLa_Curcumin_4h_R1 1 GQEADLEAGGEEVPEANGSAGKR 23 1 Q9NX58 Q9NX58 LYAR Cell growth-regulating nucleolar protein 1 0 GQEADLEAGGEEVPEANGS(1)AGKR 99.873 3.08E-05 4578400 1469.7 1759.9 1758.6 1605 1771.3 2522.5 2098.4 942.79 1719.6 1470.7 TRUE FALSE FALSE 1353.371694 1912.017914 1823.775263 1598.358935 1750.178404 1999.305066 2157.275456 1230.242331 1530.964182 1521.806716 0.889319045 1.256413114 1.198427661 1.05030351 1.150066159 1.313770695 1.417575198 0.808409056 1.006017497 1 10.57156942 -7.263923362 24.96328139 0.947733991 1.181347671 0.26138234 0.156857002 180.2644702 1811597.721 0.025352513 0.029708968 5.45E-08 7.263923362 0.233613679 GQEEISGALPVAS(ph)PASSR ddPTM_HeLa_Curcumin_4h_R1 4 GQEEISGALPVASPASSR 18 0 Q9UBK8;Q9UBK8-1;H0Y9D5;H0Y8S9 Q9UBK8 MTRR Methionine synthase reductase 1 0 GQEEISGALPVAS(1)PASSR;GQEEISGALPVAS(0.999)PAS(0.001)SR;GQEEISGALPVAS(0.468)PAS(0.468)S(0.063)R;GQEEISGALPVAS(1)PASSR ;;; 261.94 1.91E-53 215239000 8971.2 7311.4 7974 8501.1 8481.8 12402.9 10954.5 7469.14 8907.7 7256.3 TRUE FALSE FALSE 8261.120054 7943.364837 8269.523455 8465.924701 8380.660075 9830.398731 11261.85379 9746.446402 7930.547596 7508.455885 1.100242204 1.057922555 1.101361396 1.127518738 1.116162924 1.309243722 1.499889453 1.298062684 1.056215515 1 12.87430053 -5.252965933 2.075049298 1.058690736 1.405345459 0.843651908 0.057734182 0.090199009 0.744944957 0.009164896 0.028459565 5.59E-06 5.252965933 0.346654723 GQESFK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 GQESFKK 7 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 0 1 ; GQESFK(1)K;GQESFK(1)K 111.74 0.0042985 28296000 5174.4 4932.5 4838.9 5068.1 5616.6 6741.3 5973.6 5797.5 5021.1 4422 FALSE TRUE FALSE 4764.84078 5358.843321 5018.233891 5047.129545 5549.625713 5343.07839 6141.203139 7565.131062 4470.297892 4575.664171 1.041344076 1.171161851 1.096722509 1.103037582 1.212856868 1.167716465 1.342144639 1.653340538 0.976972462 1 12.15976545 -1 0.430415519 1.025460388 13.07497729 0.917366879 0.054331744 12.92044608 0.144939395 0.012181345 136.3308842 0.1 1 12.0495169 GQESS(ph)S(ph)DQEQVDVESIDFSKENK ddPTM_HeLa_Curcumin_4h_R1 1 GQESSSDQEQVDVESIDFSKENK 23 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 2 0 GQES(0.238)S(0.822)S(0.94)DQEQVDVESIDFSKENK 112.75 6.60E-06 5764000 1714.7 1312.8 1452.9 1400.2 1300.9 1949.9 1475.1 1210.5 2079.5 1691.6 TRUE FALSE FALSE 1578.979686 1426.272582 1506.745752 1394.406343 1285.387617 1545.46876 1516.487336 1579.575878 1851.384053 1750.382974 0.902076694 0.814834584 0.860809191 0.796629289 0.734346504 0.882931783 0.866374593 0.9024173 1.057702274 1 10.77345489 -8.052153072 0.788074968 0.986220984 0.833854405 0.648990856 0.052961391 0.269567662 0.364923359 0.017280462 0.012190851 8.87E-09 8.052153072 -0.15236658 GQFSTDELVAEVEKR ddPTM_HeLa_Curcumin_4h_R1 2 GQFSTDELVAEVEKR 15 1 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 0 ; ; 205.12 2.49E-09 20769300 24157.9 19699.7 20737.2 22322.7 22188.2 29211.5 21821.8 22033 24809.4 23104 FALSE FALSE TRUE 22245.77672 21402.45429 21505.73887 22230.33458 21923.62021 23152.70562 22434.06098 28750.76027 22087.87089 23906.86228 0.930518462 0.895243133 0.899563423 0.929872533 0.917042979 0.968454385 0.938394203 1.20261538 0.92391342 1 14.54513717 -4.259823851 24.91282193 0.95008701 1.202615468 0.849603776 0.033308245 48.57509677 748995.9977 0.005853172 0.049615584 5.50E-05 4.259823851 0.252528458 GQGESDPLDHEPAVS(ph)PLLPR ddPTM_HeLa_Curcumin_4h_R1 4 GQGESDPLDHEPAVSPLLPR 20 0 P00519;P00519-2 P00519 ABL1 Tyrosine-protein kinase ABL1 1 0 GQGESDPLDHEPAVS(1)PLLPR;GQGESDPLDHEPAVS(1)PLLPR;GQGESDPLDHEPAVS(1)PLLPR;GQGESDPLDHEPAVS(1)PLLPR ;;; 131.75 4.25E-05 184608500 9576 8343 7400.11 7968.4 10545.9 13334.1 6900.24 3685.46 11814.7 9749.9 TRUE FALSE FALSE 8818.049495 9064.131744 7674.364586 7935.428872 10420.14703 10568.45735 7093.842163 4809.139788 10518.65697 10088.7083 0.874051388 0.898443237 0.76068852 0.786565399 1.032852445 1.04755307 0.703146721 0.476685384 1.04261682 1 13.30045385 -4.513015781 3.795098335 0.924555411 0.503783772 0.678465295 0.099258897 0.098221959 2.993741998 0.014331744 0.080610926 3.07E-05 4.513015781 -0.420771639 GQGGAGAGDDEEED ddPTM_HeLa_Curcumin_4h_R1 2 GQGGAGAGDDEEED 14 0 P46781 P46781 RPS9 40S ribosomal protein S9 0 0 ; ; 175.93 0.0015997 43650000 17924.2 17798.1 16927.6 16080.9 15497.1 18721.9 13266.2 13298.2 17209.8 17387 FALSE FALSE TRUE 16505.48066 19336.48846 17554.95175 16014.3615 15312.3072 14838.7669 13638.41387 17352.75996 15321.928 17991.19696 0.917419819 1.074774986 0.975752297 0.890122071 0.851099971 0.824779304 0.758060395 0.964513923 0.851634721 1 14.13500355 -6.06147763 2.877508805 0.971256017 0.841861842 0.360261223 0.071634919 0.177502812 2.902680964 0.009618249 0.017351614 8.68E-07 6.06147763 -0.129394175 GQHEPSKPPPAGETVTGGFGAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 GQHEPSKPPPAGETVTGGFGAKK 23 2 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 0 1 ; GQHEPSKPPPAGETVTGGFGAK(1)K;GQHEPSKPPPAGETVTGGFGAK(1)K 104.03 6.13E-06 11505300 7097.5 5850 5961.6 5336.7 6813 9482.5 6838.8 5153.9 7325.1 5524.2 FALSE TRUE FALSE 6535.725386 6355.647933 6182.54214 5314.618149 6731.759425 7515.72261 7030.678322 6725.300384 6521.554856 5716.165539 1.143375807 1.111872616 1.081589065 0.929752316 1.177670482 1.314818922 1.229964086 1.176540522 1.14089678 1 12.48083198 -1 0.114387427 0.965656996 1.804349039 0.22372729 0.091797401 88.57966411 0.704328669 0.494201843 11.8211263 0.1 1 0.838692043 GQKS(ph)PGALETPSAAGSQGNTASQGK ddPTM_HeLa_Curcumin_4h_R1 1 GQKSPGALETPSAAGSQGNTASQGK 25 1 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 GQKS(0.444)PGALET(0.415)PS(0.121)AAGS(0.017)QGNT(0.002)AS(0.001)QGK 59.646 0.0022753 14510000 1673.2 1330.6 1155.1 1448 1268.1 1486 1073.3 1912.3 1836.9 1662 TRUE FALSE FALSE 1540.764454 1445.611135 1197.909022 1442.00856 1252.978736 1177.786849 1103.413909 2495.351467 1635.396666 1719.754376 0.895921229 0.84059163 0.696558205 0.838496811 0.728580054 0.684857597 0.64161134 1.450992945 0.950947815 1 10.74798681 -7.917716615 1.024419913 0.977067097 0.818451974 0.047212468 0.218258737 0.820674466 1.823788534 0.05452791 0.045729524 1.21E-08 7.917716615 -0.158615123 GQKSPGALET(ph)PSAAGSQGNTASQGK ddPTM_HeLa_Curcumin_4h_R1 2 GQKSPGALETPSAAGSQGNTASQGK 25 1 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 GQKSPGALET(0.944)PS(0.056)AAGSQGNTASQGK;GQKS(0.183)PGALET(0.816)PS(0.001)AAGSQGNTASQGK ; 164.91 8.86E-12 141226000 12303.5 8923.9 9277.6 10613.5 7920.9 10006.8 7696.6 11986.4 12136.9 9326.1 TRUE FALSE FALSE 11329.66499 9695.242152 9621.436017 10569.58415 7826.448441 7931.27688 7912.545882 15640.99818 10805.51244 9650.181281 1.174036493 1.004669433 0.997021272 1.095273119 0.811015691 0.821878538 0.819937538 1.620798379 1.119721187 1 13.23634033 -7.059381739 24.60347744 1.082561251 1.001981814 0.013819607 0.225892037 739.5759543 306425.151 0.03641743 0.044602144 8.72E-08 7.059381739 -0.080579437 GQLTNIVSPT(ph)AATT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 GQLTNIVSPTAATTPR 16 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 2 0 GQLT(0.119)NIVS(0.408)PT(0.472)AAT(0.054)T(0.947)PR 99.238 0.011219 4740200 2142 1186.6 1326.9 1754.1 1555.1 2771.1 2447.2 1114.2 1903.6 1355.9 TRUE FALSE FALSE 1972.45844 1289.164417 1376.076081 1746.841999 1536.556448 2196.342623 2515.861846 1453.914451 1694.779843 1403.017424 1.405868812 0.918851323 0.980797571 1.245060802 1.095179876 1.565442157 1.793179331 1.036276832 1.207953525 1 10.45431721 -5.262022797 24.99379652 1.15711571 1.49778744 0.322800333 0.222126523 49.78178052 2132728.274 0.033786874 0.080042042 5.47E-06 5.262022797 0.34067173 RGFSDS(ph)GGGPPAK ddPTM_HeLa_Curcumin_4h_R1 1 RGFSDSGGGPPAK 13 1 Q9H307;G3V5F0;G3V579 Q9H307 PNN Pinin 1 0 RGFS(0.271)DS(0.729)GGGPPAK 165.78 0.00028303 180050000 1704.4 1114.8 1518.9 1718.9 1582.1 1749.6 3024.2 25798 0 1217.8 TRUE FALSE FALSE 1569.494942 1211.158345 1575.19177 1711.787647 1563.234491 1386.713238 3109.050913 33663.69144 0 1260.118459 1.245513809 0.961146419 1.250034676 1.358433911 1.240545664 1.100462601 2.467268763 26.71470384 0 1 10.29934365 -4.26063618 4.825658123 1.157963229 28.12854139 0.997494604 0.384465779 0.002914767 0.195257862 0.02658389 0.262954741 5.49E-05 4.26063618 26.97057816 up GQPDEELKPK ddPTM_HeLa_Curcumin_4h_R1 1 GQPDEELKPK 10 1 P54577 P54577 YARS "Tyrosine--tRNA ligase, cytoplasmic;Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed" 0 0 82.494 0.017301 2852500 3145.1 2749.9 2680.1 3022.4 3075.5 3525.2 2792.6 2464.3 3477.6 2901.8 FALSE FALSE TRUE 2896.162016 2987.589103 2779.426864 3009.89411 3038.826671 2794.033783 2870.95284 3215.653726 3096.115981 3002.637334 0.964539401 0.994988329 0.925661861 1.002416801 1.012052517 0.930526558 0.956143723 1.070943097 1.03113218 1 11.55201452 HVS(ph)PVTPPR ddPTM_HeLa_Curcumin_4h_R1 2 HVSPVTPPR 9 0 Q13443 Q13443 ADAM9 Disintegrin and metalloproteinase domain-containing protein 9 1 0 HVS(0.997)PVT(0.003)PPR;HVS(0.998)PVT(0.002)PPR ; 90.913 0.008721 21069900 3664.1 3389.1 3475.9 4672 3165.4 4125.6 1750.54 330.73 5273 4066.3 TRUE FALSE FALSE 3374.082619 3682.038702 3604.719912 4652.668502 3127.654672 3269.904055 1799.655441 431.5680545 4694.565092 4207.603622 0.801901253 0.875091628 0.856715659 1.105776332 0.743333962 0.777141658 0.427715061 0.10256861 1.115733684 1 12.03878309 -4.556863723 1.394708391 0.906463209 4.35E-19 0.851960971 0.113293003 0.191745635 0.47981787 0.01519038 0.208048488 2.77E-05 4.556863723 -0.906463209 down GQPSSSNAGNK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 GQPSSSNAGNKR 12 1 Q9H0H5;F8VRD2;F8W1E5;F8VQZ5;F8W1T4;F8VZ66;F8VV37;F8VV47;F8VWY4;F8VVE5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 0 1 ; GQPSSSNAGNK(1)R;GQPSSSNAGNK(1)R 111.5 0.00097408 445860 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 GQQPPPAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 GQQPPPAKR 9 1 Q9HCJ5 Q9HCJ5 ZSWIM6 Zinc finger SWIM domain-containing protein 6 0 1 GQQPPPAK(1)R 85.212 0.010728 346620 337.71 512.91 317.73 232.46 315.33 412.18 313.13 177.19 312.16 262.85 FALSE TRUE FALSE 310.9798972 557.2436549 329.5053533 231.4981421 311.5698957 326.6892218 321.9155851 231.2144153 277.916829 271.9840179 1.143375627 2.048810291 1.211487924 0.851146122 1.145544867 1.201133891 1.183582725 0.850102947 1.021813087 1 8.087378069 -4.257100711 22.96178955 1.149400035 0.850102555 0.084294804 0.307285524 315.9447517 1671876.389 0.043453039 0.443056111 5.53E-05 4.257100711 -0.29929748 GQS(ph)PAGDGSPEPPTPR ddPTM_HeLa_Curcumin_4h_R1 1 GQSPAGDGSPEPPTPR 16 0 A0A0A0MRW6;Q9H6R4-3;Q9H6R4-2;Q9H6R4-4;Q9H6R4 A0A0A0MRW6 NOL6 Nucleolar protein 6 1 0 GQS(0.979)PAGDGS(0.021)PEPPTPR 149.99 1.87E-07 0 725.68 753.83 649.7 557.25 766.98 1019.7 558.18 399.24 773.73 769.88 TRUE FALSE FALSE 668.2416623 818.9877062 673.7784535 554.9442472 757.8342644 808.2027256 573.8410285 520.9664381 688.8537548 796.6332727 0.838832227 1.028061135 0.845782466 0.696611937 0.951296274 1.014522935 0.720332741 0.65396018 0.864706231 1 9.637771927 -1 0.174991493 0.973425416 3.90E-13 0.247489237 0.112893094 63.20549986 0.675284141 0.162679948 16.32611547 0.1 1 -0.973425416 VHGLPT(ph)TSPSGMNMAELAQQVVK ddPTM_HeLa_Curcumin_4h_R1 3 VHGLPTTSPSGMNMAELAQQVVK 23 0 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 0 VHGLPT(0.419)T(0.372)S(0.105)PS(0.105)GMNMAELAQQVVK;VHGLPT(0.472)T(0.375)S(0.077)PS(0.077)GMNMAELAQQVVK;VHGLPT(0.368)T(0.132)S(0.368)PS(0.132)GMNMAELAQQVVK ;; 105.38 2.27E-05 154753000 9958.3 7823.8 9097.5 7552.2 7764.3 9172.5 4112.9 1999.23 8950.7 7580.8 TRUE FALSE FALSE 9170.090047 8500.05441 9434.661353 7520.950997 7671.715794 7270.020105 4228.296905 2608.786024 7968.830604 7844.232236 1.169023274 1.083605655 1.202751406 0.958787396 0.978007224 0.926798173 0.539032601 0.332573787 1.015884074 1 12.93741653 -4.556766866 1.088842124 1.084951586 0.129459901 0.919920197 0.073762664 0.228626129 0.298764796 0.012677732 0.221319546 2.77E-05 4.556766866 -0.955491685 down GQSEEPAGK(ac)TK ddPTM_HeLa_Curcumin_4h_R1 2 GQSEEPAGKTK 11 1 O75152;E9PBY7;E9PQ61;A0A1B0GTU1;A0A494C0C4 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 0 1 ; GQSEEPAGK(1)TK;GQSEEPAGK(1)TK 172.11 5.07E-09 4383500 2576.8 2237 2489.4 2792.1 2330.1 3443.4 3744.9 3272.2 2887.6 2543.2 FALSE TRUE FALSE 2372.843561 2430.356312 2581.659354 2780.54703 2302.315079 2729.200025 3849.971815 4269.878717 2570.837504 2631.576011 0.901681559 0.923536429 0.981031649 1.056609051 0.874880706 1.037097167 1.462990922 1.622555723 0.976919342 1 11.36171135 -4.724421201 2.91939893 0.955050542 1.599617286 0.955944359 0.05004429 0.037743406 0.63044238 0.007778646 0.035765466 1.89E-05 4.724421201 0.644566743 GQSPPS(ph)KDGSGDYQSR ddPTM_HeLa_Curcumin_4h_R1 1 GQSPPSKDGSGDYQSR 16 1 Q8N4C8;Q8N4C8-2;Q8N4C8-3;Q8N4C8-4;Q8N4C8-5 Q8N4C8 MINK1 Misshapen-like kinase 1 1 0 GQS(0.469)PPS(0.526)KDGS(0.005)GDYQSR 85.976 0.003727 15310000 3765.7 2762.9 3034.1 3467.6 3020.5 3759.6 2365.7 1668.8 3396 3007.1 TRUE FALSE FALSE 3467.640871 3001.712765 3146.546415 3453.25199 2984.48251 2979.816581 2432.075175 2177.609438 3023.467296 3111.596501 1.114424981 0.964685737 1.011232148 1.109800705 0.959148305 0.957648776 0.781616503 0.699836703 0.971677174 1 11.60343927 -4.689593607 1.172377477 1.047338988 0.641879989 0.802604225 0.054431294 0.249642339 0.448464705 0.008596251 0.102167713 2.04E-05 4.689593607 -0.405458999 NVFEVGPGDSPT(ph)FPR ddPTM_HeLa_Curcumin_4h_R1 1 NVFEVGPGDSPTFPR 15 0 Q16584;Q16584-2 Q16584 MAP3K11 Mitogen-activated protein kinase kinase kinase 11 1 0 NVFEVGPGDS(0.266)PT(0.734)FPR 156 0.001069 6049500 2675.4 1851.4 2141.8 2787.4 2483.3 2369.5 1448.7 545.17 2728.7 2390.1 TRUE FALSE FALSE 2463.639267 2011.426766 2221.176992 2775.866477 2453.688269 1878.03899 1489.346623 711.3898233 2429.368437 2473.155797 0.99615207 0.813303702 0.898114464 1.122398549 0.992128467 0.759369463 0.602204934 0.287644565 0.982294945 1 11.27213741 -4.554080569 1.295989135 0.986000452 0.182878187 0.877814623 0.081608583 0.203964659 0.419392069 0.012567043 0.18722124 2.79E-05 4.554080569 -0.803122265 down VGS(ph)PLTLTDAQTR ddPTM_HeLa_Curcumin_4h_R1 2 VGSPLTLTDAQTR 13 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 0 VGS(0.998)PLT(0.001)LT(0.001)DAQTR;VGS(0.995)PLT(0.002)LT(0.002)DAQTR ; 160.46 0.00026085 73884000 3459.9 2803.7 3027.1 3456.7 3127.2 2944.1 1645.81 420.03 4785.8 3211.7 TRUE FALSE FALSE 3186.045264 3046.039335 3139.286989 3442.397091 3089.910182 2333.460473 1691.986999 548.0952134 4260.809713 3323.306336 0.958697436 0.916568931 0.94462763 1.035835022 0.929769895 0.70215028 0.509127606 0.164924674 1.282099597 1 11.69840357 -4.547905444 1.121213099 0.977870201 4.38E-17 0.876843518 0.104244988 0.110737443 0.154775465 0.006462879 0.112401925 2.83E-05 4.547905444 -0.977870201 down SGGLQTPECLS(ph)REGS(ph)PIPHDPEFGSK ddPTM_HeLa_Curcumin_4h_R1 1 SGGLQTPECLSREGSPIPHDPEFGSK 26 1 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 2 0 S(0.02)GGLQT(0.228)PECLS(0.868)REGS(0.879)PIPHDPEFGS(0.004)K 49.626 0.01598 40527000 4516.5 3828.6 3927.2 4633 4211.7 5402.1 2738 1318.9 5726.3 3888 TRUE FALSE FALSE 4159.014259 4159.527124 4072.745487 4613.829874 4161.478228 4281.643566 2814.820911 1721.026539 5098.139216 4023.107711 1.033781484 1.033908964 1.012338167 1.146832301 1.034393938 1.064262723 0.699663323 0.42778535 1.267214199 1 11.97409465 -4.541504178 2.682239813 1.031071351 0.433166216 0.851429934 0.087090825 0.046878079 0.606467423 0.006765431 0.046750904 2.87E-05 4.541504178 -0.597905135 down GQSTDSLPQT(ph)ICR ddPTM_HeLa_Curcumin_4h_R1 1 GQSTDSLPQTICR 13 0 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 0 GQST(0.001)DS(0.149)LPQT(0.85)ICR 141.59 0.0026776 8819600 1016.2 1183.1 1123.4 1135.9 1071 1312.3 1045.9 378.14 1319.4 1085.2 TRUE FALSE FALSE 935.7666977 1285.361892 1165.034192 1131.199947 1058.229024 1040.114187 1075.245139 493.4331453 1174.665121 1122.910619 0.833340323 1.144669816 1.037512846 1.007382001 0.94239827 0.926266231 0.957551848 0.439423349 1.0460896 1 10.13302738 -4.2610421 24.70371008 0.951761639 0.439423172 0.778620615 0.085837048 11.08314756 688878.3718 0.013256276 0.104005484 5.48E-05 4.2610421 -0.512338466 SSS(ph)PELVTHLK ddPTM_HeLa_Curcumin_4h_R1 2 SSSPELVTHLK 11 0 E9PNR6;H0YE29;Q07960 E9PNR6 ARHGAP1 Rho GTPase-activating protein 1 1 0 SS(0.019)S(0.981)PELVTHLK;SS(0.065)S(0.934)PELVTHLK ; 199.12 6.50E-06 315790000 8281.8 6924.8 6886.4 6588.7 7382.2 9187.6 8737 29348 7385 7009.2 TRUE FALSE FALSE 7626.286791 7523.348856 7141.616042 6561.437705 7294.172086 7281.988194 8982.136706 38296.0701 6574.883976 7252.769178 1.0515 1.037307085 0.984674387 0.904680343 1.005708566 1.00402867 1.238442378 5.280199763 0.906534293 1 12.82431622 -4.26059067 4.783883665 1.014602585 5.522304266 0.9983494 0.052110455 0.004561359 0.295136828 0.006854184 0.068286345 5.49E-05 4.26059067 4.507701681 up GFS(ph)DSGGGPPAK ddPTM_HeLa_Curcumin_4h_R1 2 GFSDSGGGPPAK 12 0 Q9H307;G3V5F0;G3V579 Q9H307 PNN Pinin 1 0 GFS(0.5)DS(0.5)GGGPPAK;GFS(0.911)DS(0.089)GGGPPAK ; 144.28 0.00092981 108056000 2958.6 1980.13 2704.4 2938.4 2825.7 3431.8 5026.7 39765 0 2462.43 TRUE FALSE FALSE 2724.423688 2151.283614 2804.627443 2926.241679 2792.005373 2720.005996 5167.735673 51889.16544 0 2547.999259 1.069240377 0.844303077 1.100717527 1.148446833 1.095763809 1.067506588 2.028154308 20.36467054 0 1 11.31514914 -4.260584862 4.839396022 1.052055645 21.42502153 0.996538783 0.342157863 0.002693047 0.182456646 0.018626635 0.183957002 5.49E-05 4.260584862 20.37296588 up GQVIIISDS(ph)DDDDDER ddPTM_HeLa_Curcumin_4h_R1 2 GQVIIISDSDDDDDER 16 0 Q7Z333-3;Q7Z333;Q7Z333-4 Q7Z333-3 SETX Probable helicase senataxin 1 0 GQVIIIS(0.026)DS(0.974)DDDDDER;GQVIIIS(0.005)DS(0.995)DDDDDER ; 222.11 1.20E-15 9451800 3851.8 3220.8 3539.7 3334 3845.5 3725.4 2644.4 1494.88 3232.5 3182.1 TRUE FALSE FALSE 3546.925966 3499.1916 3670.884396 3320.204791 3799.644924 2952.710046 2718.594747 1950.66203 2877.902837 3292.677738 1.07721625 1.062719124 1.114862944 1.008360081 1.153968055 0.89675039 0.825648595 0.592424217 0.874031128 1 11.6850456 -4.505888536 1.419209981 1.049436948 0.526295543 0.76188265 0.077829051 0.196785829 0.486545454 0.008246878 0.127794378 3.12E-05 4.505888536 -0.523141405 GQVLNSDELQELYEGLR ddPTM_HeLa_Curcumin_4h_R1 1 GQVLNSDELQELYEGLR 17 0 F2Z2Y4;O00764-2;O00764 F2Z2Y4 PDXK Pyridoxal kinase 0 0 242.41 2.62E-70 0 1060.5 1216.2 1014.6 916.57 1103.6 1503.8 1098.4 1186.9 1059.8 744.4 FALSE FALSE TRUE 976.560306 1321.322909 1052.201969 912.7774762 1090.440291 1191.894929 1129.218148 1548.780346 943.5425915 770.2678446 1.267819127 1.715407073 1.366020892 1.185013087 1.415663783 1.547377236 1.466007124 2.010703623 1.224953889 1 9.58921639 -1.000000001 0.08364606 0.596235273 3.667418157 0.48145951 0.197245094 86.52789449 0.529678989 2.857693477 30.76582086 0.1 1.000000001 3.071182884 SKGDS(ph)DIS(ph)DEEAAQQSK ddPTM_HeLa_Curcumin_4h_R1 1 SKGDSDISDEEAAQQSK 17 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 2 0 S(0.252)KGDS(0.771)DIS(0.976)DEEAAQQS(0.001)K 66.308 0.017257 17396000 4879 4178.3 4433.3 5245 4837.3 4883.5 2747.7 1221 5539.6 3311.2 TRUE FALSE FALSE 4492.822002 4539.453634 4597.601998 5223.29758 4779.618357 3870.607052 2824.793067 1593.277279 4931.919739 3426.263954 1.311288932 1.324898985 1.341870346 1.524487795 1.394994204 1.129687352 0.824452846 0.465018837 1.439445357 1 11.74242058 -4.539458536 2.127136222 1.223036589 0.442819988 0.738710063 0.159118748 0.207506743 1.519053532 0.027731324 0.246592641 2.89E-05 4.539458536 -0.780216601 down SS(ph)TPPLHVHVDENTPVHVHIK ddPTM_HeLa_Curcumin_4h_R1 1 SSTPPLHVHVDENTPVHVHIK 21 0 Q5BJF6-9;Q5BJF6-3;Q5BJF6-4 Q5BJF6-9 1 0 S(0.09)S(0.455)T(0.455)PPLHVHVDENTPVHVHIK 77.13 0.00039849 7648600 4441.6 3202.7 3929.9 3540.4 3703.5 3344.4 1973.2 761.86 4786.3 3747.7 TRUE FALSE FALSE 4090.042673 3479.527117 4075.545551 3525.750763 3659.338181 2650.733741 2028.562681 994.1476068 4261.254865 3877.932296 1.054696772 0.897263503 1.050958408 0.909183166 0.943631271 0.683543068 0.523104203 0.256360228 1.098847153 1 11.9210719 -4.539069147 0.816856753 1.019136004 5.45E-24 0.951962185 0.056626647 0.210361476 0.130382487 0.007882935 0.176589364 2.89E-05 4.539069147 -1.019136004 down GQVSESEDS(ph)ITK ddPTM_HeLa_Curcumin_4h_R1 3 GQVSESEDSITK 12 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 0 GQVSES(0.061)EDS(0.936)IT(0.003)K;GQVS(0.006)ES(0.067)EDS(0.847)IT(0.08)K;GQVSES(0.099)EDS(0.822)IT(0.078)K ;; 157.35 0.00029117 105773000 5900.8 5837.5 6426.3 6387.5 6798.9 6614.2 5669.6 3216.32 5285.4 5194.6 TRUE FALSE FALSE 5433.745454 6342.067489 6664.464331 6361.070217 6717.827558 5242.340363 5828.673717 4196.961162 4705.604843 5375.111963 1.010908329 1.179894955 1.239874514 1.183430273 1.249802349 0.975298821 1.084381824 0.780813719 0.87544313 1 12.39207909 -3.165922879 12.55312552 1.049836282 1.074752581 0 0.149799182 0 0 0.019072082 0 0.00068246 3.165922879 0.0249163 GRAEGEWEDQEALDY(ph)FSDKESGK ddPTM_HeLa_Curcumin_4h_R1 2 GRAEGEWEDQEALDYFSDKESGK 23 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 GRAEGEWEDQEALDY(0.759)FS(0.24)DKES(0.001)GK;GRAEGEWEDQEALDY(0.772)FS(0.227)DKES(0.001)GK ; 91.64 0.00017465 312346000 4538.1 3265.9 3419.5 3260.3 3781.5 4221.6 3559.9 3497 3612.9 3072 TRUE FALSE FALSE 4178.904596 3548.189843 3546.229678 3246.809742 3736.408082 3345.992573 3659.781213 4563.219202 3216.573909 3178.751771 1.31463697 1.116221114 1.115604468 1.021410282 1.175432481 1.052612099 1.151326519 1.435538076 1.011898424 1 11.63424465 -4.264857114 5.267653503 1.133567596 1.447586075 0.511674571 0.093256152 0.129683828 12.51283588 0.016553133 0.146599064 5.43E-05 4.264857114 0.314018479 GRAEGEWEDQEALDY(ph)FSDKESGKQK ddPTM_HeLa_Curcumin_4h_R1 1 GRAEGEWEDQEALDYFSDKESGKQK 25 3 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 GRAEGEWEDQEALDY(0.817)FS(0.131)DKES(0.051)GKQK 48.255 0.0082492 16832000 1610 1144.6 1235.9 1352.4 858.47 1537.8 1482 1029.9 2042.1 1667.3 TRUE FALSE FALSE 1482.566801 1243.534124 1281.703541 1346.804127 848.2333059 1218.842945 1523.580931 1343.911769 1818.086739 1725.238551 0.859340177 0.720789669 0.742913808 0.78064806 0.491661461 0.706477921 0.883113196 0.778971562 1.053817594 1 10.75258014 -7.804161345 0.817393241 0.974594908 0.721569491 0.572798759 0.098906388 0.3093267 0.446622525 0.029855842 0.02532213 1.57E-08 7.804161345 -0.253025417 GRAEGEWEDQEALDYFS(ph)DK ddPTM_HeLa_Curcumin_4h_R1 1 GRAEGEWEDQEALDYFSDK 19 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 GRAEGEWEDQEALDY(0.008)FS(0.992)DK 82.56 0.0016886 4985300 886.26 637.39 819.61 667.95 950.18 999.28 645.73 704.24 925.07 753.23 TRUE FALSE FALSE 816.1115858 692.4831514 849.9854676 665.1861999 938.8497241 792.0180638 663.8474459 918.9595341 823.5921354 779.4046864 1.047096072 0.888477018 1.090557296 0.853454196 1.20457285 1.016183348 0.851736534 1.179053129 1.056693846 1 9.606228796 -5.767775849 24.99996328 1.006754795 1.044468384 0.069910382 0.114180843 539.9287054 2130243.293 0.015458306 0.028523807 1.71E-06 5.767775849 0.037713589 GRAEGEWEDQEALDYFS(ph)DKESGK ddPTM_HeLa_Curcumin_4h_R1 2 GRAEGEWEDQEALDYFSDKESGK 23 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 GRAEGEWEDQEALDY(0.394)FS(0.521)DKES(0.084)GK;GRAEGEWEDQEALDY(0.323)FS(0.569)DKES(0.108)GK ; 98 2.58E-05 72018000 6379.9 4883.5 5126.1 6144.9 5707.5 6500.2 6410.3 5500 6327.9 6035.4 TRUE FALSE FALSE 5874.924183 5305.60798 5316.077775 6119.474032 5639.44179 5151.985248 6590.155766 7176.924681 5633.745202 6245.129701 0.940720924 0.849559294 0.851235768 0.979879414 0.903014358 0.824960488 1.055247222 1.149203463 0.902102193 1 12.60851582 -4.546117822 8.447479332 0.941686242 1.126307652 0.587894638 0.062247409 0.109032369 34.57628589 0.009751084 0.03764277 2.84E-05 4.546117822 0.18462141 GRAS(ph)PGGVSTSSSDGK ddPTM_HeLa_Curcumin_4h_R1 3 GRASPGGVSTSSSDGK 16 1 P54259 P54259 ATN1 Atrophin-1 1 0 GRAS(0.999)PGGVSTSSSDGK;GRAS(1)PGGVSTSSSDGK;GRAS(1)PGGVSTSSSDGK ;; 133.93 0.00019183 103917400 10085.9 9725.9 9715.4 10659.9 10019.5 10611 9514.17 5212.91 9882 8480.62 TRUE FALSE FALSE 9287.590372 10566.56346 10075.46127 10615.79216 9900.024006 8410.158989 9781.112004 6802.302262 8797.969324 8775.320914 1.058376151 1.204122739 1.148158725 1.209732643 1.128166605 0.958387627 1.114615876 0.775162792 1.002580921 1 13.09923617 -4.255578631 24.71147405 1.066481529 0.775162643 0.537990656 0.08515409 388.3424921 1637364.676 0.013047994 0.155635195 5.55E-05 4.255578631 -0.291318886 GRAS(ph)PGGVSTSSSDGKAEK ddPTM_HeLa_Curcumin_4h_R1 2 GRASPGGVSTSSSDGKAEK 19 2 P54259 P54259 ATN1 Atrophin-1 1 0 GRAS(0.999)PGGVS(0.001)TSSSDGKAEK;GRAS(0.996)PGGVS(0.001)T(0.001)S(0.001)S(0.001)S(0.001)DGKAEK ; 96.341 0.00096489 20197100 4257.3 3238.5 3858.1 3861.2 2908.7 3796.7 3145.5 2005.43 4793.3 3712.2 TRUE FALSE FALSE 3920.330213 3518.42151 4001.08458 3845.223377 2874.015652 3009.221622 3233.754264 2616.876375 4267.486982 3841.198674 1.020600741 0.915969677 1.041623962 1.001047773 0.74820802 0.78340692 0.841860716 0.681265563 1.110977938 1 11.90734087 -5.765280268 24.96242047 1.004256915 0.77067793 0.813290187 0.058825455 24.03914324 156234.8429 0.006597026 0.01229339 1.72E-06 5.765280268 -0.233578985 GRAS(ph)S(ph)HSSQTQGGGSVTK ddPTM_HeLa_Curcumin_4h_R1 2 GRASSHSSQTQGGGSVTK 18 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 GRAS(0.994)S(0.935)HS(0.052)S(0.018)QT(0.001)QGGGSVTK;GRAS(0.994)S(0.973)HS(0.027)S(0.005)QTQGGGSVTK ; 79.013 0.0049263 20138100 6786.2 4713.5 4756.6 5292 5535.7 10981.6 6017 4354.07 10792.7 7476.1 TRUE FALSE FALSE 6249.065109 5120.913937 4932.88378 5270.103106 5469.690393 8703.892372 6185.820826 5681.605899 9608.767812 7735.893919 0.807801293 0.661967963 0.637661766 0.68125328 0.707053438 1.125130782 0.79962586 0.734447235 1.242101807 1 12.9173523 -8.682905017 0.915588526 0.984258805 0.771950176 0.394325965 0.155241833 0.523956228 0.881701724 0.060306598 0.028511347 2.08E-09 8.682905017 -0.212308629 GRAS(ph)SHS(ph)SQTQGGGSVTK ddPTM_HeLa_Curcumin_4h_R1 1 GRASSHSSQTQGGGSVTK 18 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 GRAS(0.84)S(0.44)HS(0.508)S(0.202)QT(0.009)QGGGSVTK 74.703 0.0074398 10562000 5821.1 4248.1 3554.4 4621.3 4332.6 9271.3 5098.8 2791.4 8235.7 5734.4 TRUE FALSE FALSE 5360.353793 4615.286835 3686.129191 4602.178285 4280.936575 7348.327871 5241.858605 3642.48501 7332.264315 5933.669973 0.903379159 0.777813201 0.621222482 0.77560402 0.72146523 1.238411962 0.883409193 0.613867139 1.235704774 1 12.53470897 -7.732048181 1.718900533 0.969143623 0.815088248 0.232456679 0.18669775 0.490010051 3.015907737 0.035867331 0.035239635 1.85E-08 7.732048181 -0.154055375 GRAS(ph)SHSS(ph)QTQGGGSVTK ddPTM_HeLa_Curcumin_4h_R1 1 GRASSHSSQTQGGGSVTK 18 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 GRAS(0.958)S(0.447)HS(0.063)S(0.531)QT(0.002)QGGGSVTK 97.059 0.0013516 12853000 5531.6 3415.8 3095 3745.1 3534.6 8465.1 4444.4 2504.7 9071.7 5310.5 TRUE FALSE FALSE 5093.768023 3711.046531 3209.703423 3729.603769 3492.452204 6709.342839 4569.097903 3268.3715 8076.557206 5495.03948 0.926975692 0.675344835 0.584109256 0.678721924 0.635564534 1.220981735 0.831495009 0.594785809 1.469790569 1 12.42391413 -7.406380645 4.703435055 0.968658815 0.754853114 0.295853927 0.23597488 0.25649733 8.679869288 0.031699839 0.035896584 3.92E-08 7.406380645 -0.213805701 GRAS(ph)SHSSQTQGGGS(ph)VTK ddPTM_HeLa_Curcumin_4h_R1 1 GRASSHSSQTQGGGSVTK 18 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 GRAS(0.735)S(0.265)HS(0.001)SQT(0.001)QGGGS(0.979)VT(0.019)K 72.755 0.0086844 3204200 1373.5 1329.9 1060.3 1574.7 1507.1 4037.7 2920.4 566.05 1882 1054.8 TRUE FALSE FALSE 1264.786026 1444.85063 1099.595651 1568.184309 1489.128817 3200.235506 3002.338564 738.6360392 1675.549309 1091.454221 1.15880813 1.323784912 1.007459249 1.436784317 1.364352977 2.932084042 2.750769116 0.676744864 1.535153079 1 10.09203591 -5.450784624 6.861467271 1.125014439 2.185167232 0.295390406 0.590772617 0.180288448 14.53308586 0.077181937 0.172996466 3.54E-06 5.450784624 1.060152793 GRASPGGVS(ph)TSSSDGKAEK ddPTM_HeLa_Curcumin_4h_R1 1 GRASPGGVSTSSSDGKAEK 19 2 P54259 P54259 ATN1 Atrophin-1 1 0 GRAS(0.028)PGGVS(0.462)T(0.462)S(0.042)S(0.004)S(0.001)DGKAEK 84.707 0.0024007 6652700 3188.1 2921.8 2804 2664.9 2418.1 3077.3 2381 1537.2 4198.8 2828.1 TRUE FALSE FALSE 2935.758521 3174.347373 2907.918707 2653.87335 2389.265737 2439.033292 2447.804452 2005.885204 3738.202145 2926.376264 1.003206101 1.084736577 0.993692692 0.906880425 0.816458829 0.833465375 0.836462652 0.685450203 1.27741678 1 11.51489956 -5.937539361 1.769798522 1.009253277 0.790485781 0.626133755 0.0963602 0.10186286 0.641086599 0.007045813 0.014694444 1.15E-06 5.937539361 -0.218767496 GRASS(ph)HSSQTQGGGS(ph)VTK ddPTM_HeLa_Curcumin_4h_R1 1 GRASSHSSQTQGGGSVTK 18 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 GRAS(0.461)S(0.538)HS(0.002)SQT(0.005)QGGGS(0.809)VT(0.186)K 70.316 0.010242 3324000 1468.2 1493.5 1340.3 1558.8 1583 3869.1 3427.2 474.05 2056.8 1337.1 TRUE FALSE FALSE 1351.990421 1622.591485 1389.972697 1552.350099 1564.123759 3066.605046 3523.358008 618.5856627 1831.174186 1383.564125 0.977179442 1.172762039 1.00463193 1.121993603 1.130503263 2.216453137 2.546580923 0.447095766 1.323519562 1 10.4341738 -5.388693582 6.088951115 1.018312401 1.813883351 0.224107377 0.519592478 0.187211445 8.497750793 0.066391388 0.149853832 4.09E-06 5.388693582 0.795570951 GRDS(ph)PYQSR ddPTM_HeLa_Curcumin_4h_R1 1 GRDSPYQSR 9 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 0 GRDS(1)PYQSR 69.216 0.020328 717540000 344.64 294.47 438.4 304.62 316.55 447.69 331.84 294.01 351.83 322.63 TRUE FALSE FALSE 317.3613803 319.9226747 454.6474897 303.3595632 312.775348 354.8340475 341.1505373 383.6522955 313.2351292 333.8413685 0.950635273 0.958307462 1.36186684 0.908693744 0.936898112 1.062882198 1.021894137 1.149205376 0.938275357 1 8.383018929 GRDVESVQT(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 GRDVESVQTPSK 12 1 P46013 P46013 MKI67 Antigen KI-67 1 0 GRDVESVQT(0.647)PS(0.353)K 97.073 0.0089544 22578000 3353 2884.8 2806 4993.8 3769.1 7508 6961.5 1755.1 4843.8 3059.7 TRUE FALSE FALSE 3087.606512 3134.149258 2909.992828 4973.136979 3724.155944 5950.756167 7156.820954 2290.221911 4312.447259 3166.024347 0.975231449 0.98993214 0.919131538 1.570782923 1.176287841 1.879567405 2.260507238 0.723374699 1.362101736 1 11.62845663 -6.035778463 1.530518965 0.980970302 1.62777652 0.218538482 0.40684165 0.302475419 1.404628269 0.057315949 0.11844933 9.21E-07 6.035778463 0.646806218 GRDWNVDLIPK ddPTM_HeLa_Curcumin_4h_R1 3 GRDWNVDLIPK 11 1 V9GYJ7;V9GYF8;Q5SX90;Q5SX86;Q5SX87;P50395;P50395-2;G5E9U5;P31150 V9GYJ7 GDI2;GDI1 Rab GDP dissociation inhibitor beta;Rab GDP dissociation inhibitor alpha 0 0 ;; ;; 107.34 0.0066343 93780000 18953 14017.2 15483.1 15788.5 15191 20412.1 15784.5 16421.2 17711 16271.5 FALSE FALSE TRUE 17452.85005 15228.78431 16056.91731 15723.17137 15009.85725 16178.40037 16227.37059 21427.94829 15768.14761 16836.93341 1.036581284 0.904486817 0.953672317 0.933850065 0.89148403 0.96088759 0.96379609 1.272675241 0.93652135 1 14.03934178 -4.258805289 24.91499368 0.985456242 1.272675348 0.764918955 0.050351702 106.203188 1004480.192 0.008251732 0.076199637 5.51E-05 4.258805289 0.287219106 GREDVSNFDDEFTSEAPILT(ph)PPREPR ddPTM_HeLa_Curcumin_4h_R1 5 GREDVSNFDDEFTSEAPILTPPREPR 26 2 Q16513-3;Q16513-2;Q16513;Q16513-4;Q16513-5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 0 GREDVSNFDDEFT(0.001)S(0.001)EAPILT(0.999)PPREPR;GREDVSNFDDEFT(0.001)SEAPILT(0.998)PPREPR;GREDVSNFDDEFT(0.035)S(0.035)EAPILT(0.93)PPREPR;GREDVSNFDDEFTSEAPILT(1)PPREPR;GREDVSNFDDEFTSEAPILT(1)PPREPR ;;;; 136.1 1.68E-07 139273700 4182.2 3338.25 3540.65 4117.79 3814.1 4693.6 3154.63 3598.34 4550.22 3952.75 TRUE FALSE FALSE 3851.174457 3626.793455 3671.869604 4100.751676 3768.619349 3720.094452 3243.140428 4695.457301 4051.07225 4090.107768 0.941582637 0.886723202 0.897743974 1.002602354 0.921398545 0.90953458 0.792922977 1.148003321 0.990456115 1 11.99792314 -8.723202619 0.866222392 0.996379892 0.931110706 0.060811397 0.086699481 1.051843498 1.56984797 0.037439657 0.016390318 1.89E-09 8.723202619 -0.065269186 GREEYEGPNK(ac)KPR ddPTM_HeLa_Curcumin_4h_R1 1 GREEYEGPNKKPR 13 3 P23246 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 1 GREEYEGPNK(0.852)K(0.148)PR 103.21 0.00085586 42810000 3206.6 3024.9 2775.4 2997.1 2800.7 4332.9 3109.8 3669.1 3827.7 2709.4 FALSE TRUE FALSE 2952.794226 3286.358877 2878.258765 2984.698794 2767.303482 3434.207698 3197.052618 4787.7917 3407.810886 2803.551448 1.053233472 1.172212794 1.026647386 1.064613527 0.987070697 1.224949055 1.140358106 1.707759529 1.215533565 1 11.45303983 -1.464687042 0.976921244 1.039339464 200 0.799935271 0.089642304 111.79595 0.456712132 0.010277987 49367.56041 0.034301488 1.464687042 198.9606605 GREEYEGPNKK(ac)PR ddPTM_HeLa_Curcumin_4h_R1 1 GREEYEGPNKKPR 13 3 P23246 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 1 GREEYEGPNK(0.069)K(0.931)PR 78.548 0.0080386 38683000 2491.4 2141.3 2037.7 2495.4 2674.1 3370.5 2418.6 2452.4 2699.5 2211.1 FALSE TRUE FALSE 2294.203061 2326.384431 2113.218955 2485.074696 2642.213104 2671.420307 2486.459407 3200.125471 2403.371604 2287.93556 1.002739369 1.016805049 0.923635696 1.086164636 1.154845945 1.16761169 1.086769859 1.39869563 1.050454237 1 11.1598307 -1 0.427179247 0.99615759 7.946552224 0.741180217 0.063510345 23.68476161 0.267285593 0.013435771 142.7688047 0.1 1 6.950394634 GRGFGS(ph)EEGSR ddPTM_HeLa_Curcumin_4h_R1 1 GRGFGSEEGSR 11 1 Q9Y5S9 Q9Y5S9 RBM8A RNA-binding protein 8A 1 0 GRGFGS(0.993)EEGS(0.007)R 73.415 0.015665 21746000 1351.2 1072 1100.5 1091.3 1021.5 1598.1 1091.7 1241.7 1658.7 1257 TRUE FALSE FALSE 1244.251094 1164.658903 1141.285498 1086.78449 1009.31928 1266.636046 1122.330164 1620.288614 1476.74476 1300.680656 0.95661536 0.895422637 0.877452503 0.83555059 0.77599315 0.973825542 0.862879107 1.245723619 1.135363052 1 10.34505108 -4.252705889 24.49937675 0.937344858 1.245723828 0.498736982 0.095981893 522.7606436 1466416.391 0.011895145 0.185818057 5.59E-05 4.252705889 0.30837897 GRGGLGPS(ph)WAS(ph)ANS(ph)GS(ph)GGSR ddPTM_HeLa_Curcumin_4h_R1 1 GRGGLGPSWASANSGSGGSR 20 1 Q69YN4 Q69YN4 KIAA1429 Protein virilizer homolog 4 0 GRGGLGPS(0.999)WAS(0.999)ANS(0.996)GS(0.991)GGS(0.014)R 42.797 0.0095795 0 388.43 145.91 126.34 354.7 276.49 375 172.11 167.23 252.49 282.68 TRUE FALSE FALSE 357.6853556 158.5218102 131.0222715 353.2323454 273.1930373 297.2207729 176.9389434 218.2176572 224.7924787 292.503109 1.222842919 0.541949146 0.447934629 1.207619114 0.933983363 1.016128594 0.604913035 0.746035343 0.768513126 1 8.192308149 -7.278165289 24.72060547 1.10523138 0.796394926 0.088344182 0.244943426 685.8408235 1013658.59 0.040103267 0.045928517 5.27E-08 7.278165289 -0.308836454 GSLGIS(ph)QEEQ ddPTM_HeLa_Curcumin_4h_R1 2 GSLGISQEEQ 10 0 H3BRR0;Q9NZD8-2;Q9NZD8 H3BRR0 SPG21 Maspardin 1 0 GS(0.001)LGIS(0.999)QEEQ;GS(0.001)LGIS(0.999)QEEQ ; 100.69 0.012121 56614000 14510.6 12096.9 12231.2 13356.1 11935 12134.1 7232.3 1973.73 12219.9 13345.3 TRUE FALSE FALSE 13362.0707 13142.50213 12684.49903 13300.836 11792.68292 9617.350881 7435.218873 2575.511191 10879.40754 13809.04818 0.96763155 0.95173121 0.918564326 0.96319716 0.853982314 0.696452844 0.538430946 0.186508958 0.787846302 1 13.75332626 -4.532737276 0.893135039 0.97896514 3.77E-18 0.920142876 0.068556291 0.12718196 0.097866232 0.005112193 0.110030535 2.93E-05 4.532737276 -0.97896514 down TGS(ph)NISGASSDISLDEQYK ddPTM_HeLa_Curcumin_4h_R1 1 TGSNISGASSDISLDEQYK 19 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 0 T(0.144)GS(0.851)NIS(0.004)GASSDISLDEQYK 208.98 9.48E-14 8640700 3812.2 3043.1 3900.8 3701.9 4242.8 3110.5 2323.7 730.84 3203.3 3430.7 TRUE FALSE FALSE 3510.460347 3306.132004 4045.367079 3686.582519 4192.207381 2465.347237 2388.896768 953.6697516 2851.906004 3549.91657 0.98888531 0.931326678 1.139566804 1.038498355 1.180931241 0.694480332 0.672944482 0.26864568 0.803372684 1 11.7935694 -4.532573826 1.343234238 1.012895784 0.177349434 0.782447543 0.120568911 0.219373302 0.484066619 0.014234417 0.216655763 2.93E-05 4.532573826 -0.83554635 down GRLS(ph)PVPVPR ddPTM_HeLa_Curcumin_4h_R1 1 GRLSPVPVPR 10 1 Q9UKM9-2;Q9UKM9;Q5QPM0;Q5QPM1;Q5QPL9 Q9UKM9-2 RALY RNA-binding protein Raly 1 0 GRLS(1)PVPVPR 72.496 0.017969 83734000 2230.7 1585.5 1311.2 1558.1 1301.6 1584.7 1435.2 605.53 1993 1422.3 TRUE FALSE FALSE 2054.137741 1722.543555 1359.794225 1551.652995 1286.07927 1256.015357 1475.467849 790.1533095 1774.372886 1471.724819 1.395734933 1.170425023 0.923945977 1.054309185 0.873858519 0.853430846 1.002543295 0.536889301 1.20564175 1 10.52329223 -5.990842499 0.952582461 1.185403644 0.794019498 0.540192458 0.14987456 0.407673849 0.721551092 0.03280334 0.087184296 1.02E-06 5.990842499 -0.391384146 GRLT(ph)PS(ph)PDIIVLS(ph)DNEASSPR ddPTM_HeLa_Curcumin_4h_R1 1 GRLTPSPDIIVLSDNEASSPR 21 1 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 3 0 GRLT(1)PS(1)PDIIVLS(0.79)DNEAS(0.115)S(0.095)PR 89.879 0.00041976 3672600 1482 1215.8 1345.1 1260.3 1119.5 1577.5 1332.5 890.57 1581.8 1103.5 TRUE FALSE FALSE 1364.698136 1320.888335 1394.950589 1255.085213 1106.150694 1250.308718 1369.886364 1162.100693 1408.280497 1141.846543 1.195167726 1.156800222 1.221662051 1.099171531 0.968738488 1.094988399 1.199711443 1.017738067 1.233336044 1 10.15715306 -3.998106586 15.23581485 1.104759326 0.924853126 0.065876052 0.089274263 1025363.351 28782630.98 0.013318673 3331516.92 0.000100437 3.998106586 -0.1799062 GRLT(ph)PS(ph)PDIIVLSDNEASSPR ddPTM_HeLa_Curcumin_4h_R1 1 GRLTPSPDIIVLSDNEASSPR 21 1 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 2 0 GRLT(1)PS(1)PDIIVLSDNEASSPR 107.49 8.48E-05 16451000 3700.7 3094 3420.6 3263 3468.1 4650.7 3851.2 2744.3 3907.9 2892.5 TRUE FALSE FALSE 3407.78569 3361.431573 3547.370445 3249.498571 3426.745173 3686.092396 3959.254307 3581.024437 3479.213147 2993.01416 1.138579876 1.123092439 1.185216727 1.085694353 1.144914454 1.231565305 1.3228318 1.196460907 1.1624446 1 11.54738339 -1.466196997 0.024440883 6.52E-07 2.690622342 0.296793308 0.068521557 642.2228068 1.317095857 51.88684107 100.6492647 0.034182436 1.466196997 2.690621691 S(ph)GSTSPLGFAR ddPTM_HeLa_Curcumin_4h_R1 1 SGSTSPLGFAR 11 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 0 S(0.437)GS(0.153)T(0.093)S(0.317)PLGFAR 118.23 0.0044293 9508200 2623.5 1697.8 2266.9 2509 1873.6 1907 1186.1 706.55 2578.1 2524.4 TRUE FALSE FALSE 2415.847207 1844.550267 2350.913308 2498.618423 1851.258544 1511.466704 1219.378774 921.9738424 2295.28888 2612.122712 0.924859768 0.706149929 0.900001098 0.956547107 0.708718061 0.578635413 0.466815272 0.352959621 0.878706375 1 11.35100696 -4.531920421 0.470611966 0.967830195 4.72E-17 0.83407309 0.085982787 0.928039944 0.162368038 0.019696641 0.473764102 2.94E-05 4.531920421 -0.967830195 down GRLT(ph)PSPDIIVLSDNEAS(ph)S(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 GRLTPSPDIIVLSDNEASSPR 21 1 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 3 0 GRLT(0.901)PS(0.102)PDIIVLS(0.448)DNEAS(0.826)S(0.722)PR 67.606 0.0030999 19671000 1955.4 1703.5 1659 2008.2 1780.2 2142.3 1555.7 1284.7 2010.1 1721.5 TRUE FALSE FALSE 1800.628027 1850.742949 1720.483999 1999.890601 1758.972278 1697.962831 1599.348755 1676.399116 1789.597059 1781.321997 1.010838035 1.038971591 0.965846715 1.122700222 0.987453296 0.953203763 0.897843713 0.941098307 1.004645461 1 10.79873261 -5.196464892 2.993020473 1.013197361 0.921488568 0.502938026 0.040826549 0.162798238 2.858077598 0.005519321 0.015643093 6.36E-06 5.196464892 -0.091708793 GRLT(ph)PSPDIIVLSDNEASSPR ddPTM_HeLa_Curcumin_4h_R1 2 GRLTPSPDIIVLSDNEASSPR 21 1 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 0 GRLT(0.634)PS(0.119)PDIIVLS(0.122)DNEAS(0.122)S(0.003)PR;GRLT(0.982)PS(0.018)PDIIVLSDNEASSPR ; 115.38 0.00011753 42113000 5684.7 5037.7 5315 5886.7 5401.7 6805.2 5408.8 2329.53 5955.4 5183.5 TRUE FALSE FALSE 5234.749997 5473.13634 5511.978576 5862.342395 5337.288255 5393.72481 5560.556371 3039.792973 5302.10752 5363.626239 0.975972181 1.020417176 1.027658962 1.092981154 0.995089519 1.005611608 1.036715857 0.566742133 0.988530387 1 12.38899299 -4.258841392 24.99738611 1.004078011 0.566741978 0.942876615 0.033050682 43.49290568 418456.6012 0.005050567 0.046153869 5.51E-05 4.258841392 -0.437336033 GRNDS(ph)GEENVPLDLTR ddPTM_HeLa_Curcumin_4h_R1 3 GRNDSGEENVPLDLTR 16 1 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 0 GRNDS(1)GEENVPLDLTR;GRNDS(1)GEENVPLDLTR;GRNDS(1)GEENVPLDLTR ;; 144.57 0.00016402 83578700 7034.4 5525.9 6890.9 6693.4 7882.7 10778 9955.2 10507.45 7689.8 7128.8 TRUE FALSE FALSE 6477.619817 6003.534173 7146.282816 6665.704484 7788.703951 8542.521307 10234.51612 13711.12313 6846.248179 7376.525269 0.878139718 0.81387021 0.96878714 0.90363745 1.055877078 1.158068467 1.387444053 1.858750921 0.928112889 1 12.84872568 -4.023422675 0.867541351 0.929147252 2.736223476 0.967391107 0.053866981 0.455738949 0.192308573 0.010407881 0.86113252 9.47E-05 4.023422675 1.807076224 GRNDS(ph)GEENVPLDLTREPSDNLR ddPTM_HeLa_Curcumin_4h_R1 1 GRNDSGEENVPLDLTREPSDNLR 23 2 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 0 GRNDS(1)GEENVPLDLTREPSDNLR 50.945 0.0069712 45959000 721.55 801.9 533.09 664.49 724.64 890.77 461.72 353.53 809.96 861.69 TRUE FALSE FALSE 664.4385561 871.2126628 552.8467844 661.7405164 715.9991413 706.014261 474.6746205 461.3196695 721.1094144 891.6336634 0.745192318 0.977097096 0.620038035 0.742166367 0.803019413 0.791821002 0.532365073 0.517387004 0.808750773 1 9.800307276 -5.500642654 0.073584317 1.383737183 1.81E-16 0.439953975 0.116029936 32.86098274 0.63731242 4.278021855 7.929338838 3.16E-06 5.500642654 -1.383737183 GRNKGS(ph)AALGGALALAERS(ph)S(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 GRNKGSAALGGALALAERSSR 21 3 H7BZ50;H7C173;A0A494C0V9;Q6NZ67 H7BZ50 MZT2B Mitotic-spindle organizing protein 2B 3 0 GRNKGS(1)AALGGALALAERS(1)S(1)R 47.726 0.015985 22137000 4895.3 4458.9 4972.1 4560.5 4916 5316.7 4015.6 3654.2 5177.3 4566.2 TRUE FALSE FALSE 4507.83184 4844.307448 5156.3704 4541.629859 4857.379911 4213.956488 4128.266929 4768.348758 4609.363143 4724.87511 0.954063702 1.025277353 1.091324168 0.961216911 1.028044085 0.891866217 0.873730381 1.009201015 0.975552377 1 12.20606048 -5.257358536 24.96788756 0.991702935 0.919812321 0.319074117 0.050934245 345.3042878 2112666.05 0.007342559 0.018020866 5.53E-06 5.257358536 -0.071890614 GRPSGK(ac)GIVEFSGKPAAR ddPTM_HeLa_Curcumin_4h_R1 1 GRPSGKGIVEFSGKPAAR 18 3 Q15233;Q15233-2;C9IZL7;H7C367 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 1 GRPSGK(1)GIVEFSGKPAAR 70.167 0.0049611 7472400 4617.7 3078.2 3257 3114.8 2837.6 3082 2434.4 1967.6 3641.2 4248.1 FALSE TRUE FALSE 4252.204172 3344.265892 3377.707285 3101.911783 2803.763473 2442.758459 2502.702712 2567.512182 3241.76947 4395.721159 0.967350753 0.760800281 0.768407996 0.705666186 0.637839247 0.555712788 0.569349743 0.584093506 0.737482964 1 12.10188416 -6.646620294 0.699653536 1.000060973 0.561834189 0.630885519 0.089756135 0.084767869 0.084017466 0.008321835 0.01535459 2.26E-07 6.646620294 -0.438226785 GRPYDYNGPR ddPTM_HeLa_Curcumin_4h_R1 1 GRPYDYNGPR 10 1 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 0 88.056 0.018917 1676900 919.83 475.15 738.01 379.2 613.67 856.81 445.25 429.02 757.68 700.82 FALSE FALSE TRUE 847.0244849 516.2198488 765.3612998 377.6309709 606.3523861 679.0979478 457.7425167 559.826223 674.5643996 725.1734428 1.168030205 0.711857079 1.055418269 0.520745726 0.836148086 0.936462793 0.631217981 0.771989417 0.930211119 1 9.502182282 -7.259437444 24.9895723 1.079347598 0.783519647 0.351779514 0.152972868 112.2450825 1401123.225 0.02416477 0.028810798 5.50E-08 7.259437444 -0.295827952 GRS(ph)IDQDYER ddPTM_HeLa_Curcumin_4h_R1 1 GRSIDQDYER 10 1 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;A0A3B3IRI3;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISZ5;Q9UDY2-5;A0A3B3IRV6;A0A3B3ISF1 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 GRS(1)IDQDYER 80.916 0.013409 182850000 1573.5 1229.6 1574.5 1422.7 1270.7 1502.8 1191 1696.2 1556.3 1553.6 TRUE FALSE FALSE 1448.955815 1335.881145 1632.852355 1416.813244 1255.547732 1191.10234 1224.416255 2213.363572 1385.577784 1607.587484 0.90132315 0.830985037 1.015716016 0.88132886 0.781013627 0.740925363 0.761648288 1.376823092 0.861898837 1 10.65068154 -8.991293049 0.742968331 1.002208757 0.895804079 0 0.179798809 1.990473701 1.969446514 0.12170073 0.035367266 1.02E-09 8.991293049 -0.106404678 GRS(ph)PDELPSAGGDGGK ddPTM_HeLa_Curcumin_4h_R1 2 GRSPDELPSAGGDGGK 16 1 B4E2I7;A0A2R8Y5N1;A0A140T8Z0;A0A0G2JH68;O60610-2;O60610-3;O60610 B4E2I7 DIAPH1 Protein diaphanous homolog 1 1 0 GRS(0.999)PDELPS(0.001)AGGDGGK;GRS(1)PDELPSAGGDGGK ; 139.46 0.003813 6975400 4396.3 3955.6 3404.36 3901.4 3692.8 4317 3426.6 2951.8 4517.3 3688.8 TRUE FALSE FALSE 4048.328216 4297.504438 3530.528576 3885.257041 3648.765772 3421.605537 3522.741174 3851.790232 4021.763492 3816.985525 1.060608742 1.125889635 0.924952047 1.017886239 0.955928637 0.896415644 0.92291185 1.009118375 1.053649134 1 11.898218 -6.272943967 1.537037249 1.034451158 0.944889386 0.398841942 0.053122743 0.32742675 1.514069139 0.00894318 0.016391149 5.33E-07 6.272943967 -0.089561772 GRS(ph)PQPPAEEDEDDFDDTLVAIDTYNCDLHFK ddPTM_HeLa_Curcumin_4h_R1 1 GRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFK 32 1 M0R3F1;A0A0A0MRA5;B7Z4B8;Q9BUJ2-3;Q9BUJ2-4;Q9BUJ2-2;Q9BUJ2;M0R0K8;M0QYI8;M0QYZ0 M0R3F1 HNRNPUL1 Heterogeneous nuclear ribonucleoprotein U-like protein 1 1 0 GRS(0.999)PQPPAEEDEDDFDDT(0.001)LVAIDTYNCDLHFK 68.326 2.24E-05 13552000 768.8 461.32 737.06 687.18 921.01 864.32 594.04 400.45 706.32 677.54 TRUE FALSE FALSE 707.9486688 501.1944452 764.376092 684.3366312 910.0275573 685.0502891 610.7071636 522.5453616 628.8384631 701.0844646 1.009790838 0.71488454 1.090276751 0.976111533 1.298028416 0.977129467 0.871089283 0.745338669 0.896951074 1 9.453444456 -4.564116818 2.750448626 1.007617095 0.755419807 0.247382467 0.138226206 0.278868597 3.874218726 0.018172231 0.115970427 2.73E-05 4.564116818 -0.252197287 GRS(ph)TDEY(ph)S(ph)EADEEEEEEEGKPSR ddPTM_HeLa_Curcumin_4h_R1 1 GRSTDEYSEADEEEEEEEGKPSR 23 2 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 3 0 GRS(0.791)T(0.348)DEY(0.924)S(0.937)EADEEEEEEEGKPSR 71.297 0.0006266 35843000 1679.9 1646.1 1931.5 1815.1 2099.9 2226.1 1880.3 2019.7 2062.5 1908.3 TRUE FALSE FALSE 1546.934142 1788.381549 2003.083089 1807.589597 2074.860064 1764.381767 1933.056157 2635.497232 1836.24891 1974.613283 0.78341119 0.905686984 1.014417915 0.915414483 1.050767804 0.893532816 0.978954297 1.334690319 0.929928369 1 10.94735442 -4.257736508 3.077236975 0.916618998 1.402189301 0.721065946 0.072936971 0.183649377 2.574355234 0.013254485 0.216985302 5.52E-05 4.257736508 0.485570303 GRS(ph)VSLTTFYRT(ph)ARNIMSMCFSK ddPTM_HeLa_Curcumin_4h_R1 1 GRSVSLTTFYRTARNIMSMCFSK 23 3 Q92833-2;Q92833-3;Q92833 Q92833-2 JARID2 Protein Jumonji 2 0 GRS(0.288)VS(0.224)LT(0.224)T(0.224)FY(0.059)RT(0.959)ARNIMS(0.016)MCFS(0.007)K 45.347 0.0075668 0 805.25 913.9 998.23 962.71 952.49 1058.9 770.08 849.42 1054 953.3 TRUE FALSE FALSE 741.5136128 992.8934437 1035.225282 958.7265611 941.1321788 839.2722037 791.6863722 1108.404248 938.378837 986.427104 0.751716584 1.006555314 1.049469624 0.971918307 0.954081832 0.850820299 0.802579703 1.123655507 0.951290605 1 9.946068631 GRSECDSS(ph)PEPK ddPTM_HeLa_Curcumin_4h_R1 3 GRSECDSSPEPK 12 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 GRSECDS(0.1)S(0.9)PEPK;GRSECDS(0.012)S(0.988)PEPK;GRSECDS(0.063)S(0.937)PEPK ;; 112.62 0.0020981 269594000 22865 20967.2 19860.4 20128 20019.4 24723.3 17327.1 17720.1 23774.7 20601.7 TRUE FALSE FALSE 21055.21112 22779.51134 20596.44389 20044.71567 19780.68173 19595.40889 17813.25179 23122.87692 21166.67489 21317.60754 0.987691094 1.068577292 0.966170517 0.940289178 0.927903457 0.919212386 0.835612146 1.084684427 0.992919813 1 14.37975791 -6.524880085 24.95156235 1.000450462 0.935614617 0.217918604 0.061183028 71.05883139 885916.4338 0.008823273 0.012526225 2.99E-07 6.524880085 -0.064835845 GRSQS(ph)DLSSSSSR ddPTM_HeLa_Curcumin_4h_R1 1 GRSQSDLSSSSSR 13 1 J3KP75 J3KP75 PHACTR2 Phosphatase and actin regulator 1 0 GRS(0.003)QS(0.997)DLSSSSSR 82.837 0.0084651 2965900 420.19 430.78 333.64 592.45 445.6 464.28 334.87 393.8 595.36 457.45 TRUE FALSE FALSE 386.9315181 468.0147037 346.0049919 589.9985989 440.286511 367.9830945 344.2655509 513.8678072 530.0504975 473.3463535 0.817438468 0.988736261 0.730976355 1.246441627 0.930157184 0.777407688 0.72730158 1.08560635 1.119794192 1 8.886752398 -4.658012767 0.008936801 1.776934054 8.66E-07 0.007734204 0.167822119 28658.69283 46.20892249 4342.733593 4855.503844 2.20E-05 4.658012767 -1.776933188 GRT(ph)SSTNEDEDLNPEQK ddPTM_HeLa_Curcumin_4h_R1 1 GRTSSTNEDEDLNPEQK 17 1 Q99081;Q99081-3;B4DGI9;F5GY10;Q99081-4;Q99081-2;B4DZP2 Q99081 TCF12 Transcription factor 12 1 0 GRT(0.313)S(0.313)S(0.187)T(0.187)NEDEDLNPEQK 105.95 0.0011814 73568000 10949 8325.5 9771.3 9780.2 9262.7 11957 9657.1 7747.5 12069 9912.8 TRUE FALSE FALSE 10082.3751 9045.119122 10133.43297 9739.732124 9152.248352 9476.983417 9928.052235 10109.67708 10745.0609 10257.26906 0.982949266 0.881825276 0.987926992 0.949544373 0.892269501 0.923928519 0.967904047 0.985610987 1.047555722 1 13.32435905 -7.490059192 19.54419048 0.992477992 0.941191966 0.390187753 0.037744516 26.73331378 15920.81841 0.005756462 0.006355165 3.24E-08 7.490059192 -0.051286026 GRTSS(ph)TNEDEDLNPEQK ddPTM_HeLa_Curcumin_4h_R1 1 GRTSSTNEDEDLNPEQK 17 1 Q99081;Q99081-3;B4DGI9;F5GY10;Q99081-4;Q99081-2;B4DZP2 Q99081 TCF12 Transcription factor 12 1 0 GRT(0.102)S(0.102)S(0.6)T(0.195)NEDEDLNPEQK 145.73 0.00012142 74355000 8932.6 7007.6 7582 7360 8171.2 9736.9 7380.9 6150.9 9651.3 7091.3 TRUE FALSE FALSE 8225.575284 7613.305719 7862.99559 7329.54627 8073.763777 7717.357183 7587.988189 8026.281095 8592.576536 7337.722147 1.120998468 1.037557101 1.071585355 0.998885775 1.100309281 1.05173745 1.034106776 1.093838242 1.17101416 1 12.84111656 -9.662484203 1.523873544 1.000154016 1.070143632 0 0.063199465 0.374470558 1.57030353 0.026117086 0.005922571 2.18E-10 9.662484203 0.069989616 GRVSIQKT(ph)FY(ph)NEK ddPTM_HeLa_Curcumin_4h_R1 1 GRVSIQKTFYNEK 13 2 A0A0J9YVW2 A0A0J9YVW2 2 0 GRVS(0.001)IQKT(0.999)FY(1)NEK 71.558 0.0077342 0 983.38 821.44 638.39 1091.2 800.27 1087.5 1072.8 886.4 1029.6 870.52 TRUE FALSE FALSE 905.5444353 892.4416133 662.049295 1086.684904 790.7273029 861.9402413 1102.899881 1156.65928 916.6554559 900.7705052 1.00529983 0.990753592 0.734981098 1.206394856 0.877834363 0.956892168 1.224396086 1.284077657 1.017634848 1 9.815015778 -4.705109319 5.185498278 0.985758923 1.265450017 0.497559921 0.11256764 0.112691453 6.145272303 0.014122883 0.054589119 1.97E-05 4.705109319 0.279691094 GS(ph)DSLIK ddPTM_HeLa_Curcumin_4h_R1 1 GSDSLIK 7 0 Q99623-2;Q99623 Q99623-2 PHB2 Prohibitin-2 1 0 GS(1)DSLIK 117.81 0.013179 5977600 3036.7 3065.7 2787.9 3065.2 3997.9 3174.1 2820.2 2281 2670.4 2827.1 TRUE FALSE FALSE 2796.341991 3330.685448 2891.222026 3052.517015 3950.227654 2515.755881 2899.327222 2976.4664 2377.463801 2925.341515 0.955902747 1.138562944 0.98833658 1.043473728 1.350347518 0.859987071 0.991107263 1.017476553 0.812713247 1 11.51438934 -7.302168359 24.78651976 0.979176293 1.053889567 0.138404126 0.13077214 914.5758264 556583.3003 0.019949296 0.02281306 4.99E-08 7.302168359 0.074713274 GS(ph)FSQADVHR ddPTM_HeLa_Curcumin_4h_R1 1 GSFSQADVHR 10 0 Q2TAM5;E9PKH5;A0A087X0W8;Q04206-2;Q04206-3;Q04206-4;Q04206 Q2TAM5 RELA Transcription factor p65 1 0 GS(0.953)FS(0.047)QADVHR 87.831 0.010496 4227000 2720.3 1853.4 1982.8 2098.5 2314 2981.7 2443.7 1893.3 2315.5 2253.5 TRUE FALSE FALSE 2504.985385 2013.599637 2056.284312 2089.816963 2286.407061 2363.261809 2512.263645 2470.558454 2061.495443 2331.808957 1.074266988 0.863535424 0.881840815 0.896221346 0.980529324 1.013488606 1.077388281 1.059502944 0.884075617 1 11.18723388 -4.858777902 4.472133931 0.997035733 1.068362963 0.071796399 0.0777668 0.379988289 13.19873213 0.012103689 0.039634677 1.38E-05 4.858777902 0.071327231 GS(ph)GDTSSLIDPDTSLSELR ddPTM_HeLa_Curcumin_4h_R1 1 GSGDTSSLIDPDTSLSELR 19 0 C9JSU1;Q9Y608-4;Q9Y608;Q9Y608-2;Q9Y608-5 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 0 GS(0.999)GDT(0.001)SSLIDPDTSLSELR 116.06 0.00029155 4455000 1558.1 1252.6 1212 1460.9 1872.2 1292.5 1502.9 1429.5 1363.5 1292.6 TRUE FALSE FALSE 1434.774741 1360.869163 1256.917786 1454.855183 1849.875238 1024.420931 1545.067329 1865.347969 1213.927461 1337.517754 1.072714539 1.017458765 0.939739142 1.087727754 1.383065931 0.765912024 1.155175193 1.394634175 0.90759727 1 10.38534233 -5.998192662 24.99843291 1.026638714 1.155515164 0.194706189 0.168934085 97.79990737 1352684.071 0.023249631 0.04192585 1.00E-06 5.998192662 0.12887645 GS(ph)GGLFSPSTAHVPDGALGQR ddPTM_HeLa_Curcumin_4h_R1 1 GSGGLFSPSTAHVPDGALGQR 21 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 GS(1)GGLFSPSTAHVPDGALGQR 90.762 0.00021453 7300000 2462.6 2291.1 2017.9 1753.3 2634 3505.3 2351.6 1829.6 2625.4 1782.5 TRUE FALSE FALSE 2267.682611 2489.132475 2092.685149 1746.045309 2602.59127 2778.261267 2417.579567 2387.436618 2337.400188 1844.441742 1.229468277 1.349531632 1.134589996 0.946652458 1.411045527 1.506288436 1.31073783 1.294395243 1.267267019 1 10.84896851 -13.52287875 0.088487359 0.038094597 1.538196451 0.070679279 0.160007154 118.4692133 0.795632506 21.7173011 1.930972816 3.00E-14 13.52287875 1.500101854 GS(ph)GS(ph)EQEGEDEEGGER ddPTM_HeLa_Curcumin_4h_R1 2 GSGSEQEGEDEEGGER 16 0 Q6PD62 Q6PD62 CTR9 RNA polymerase-associated protein CTR9 homolog 2 0 GS(1)GS(1)EQEGEDEEGGER;GS(1)GS(1)EQEGEDEEGGER ; 154.88 0.00074835 5376700 1657.01 1345.77 1598.59 1671.71 1573.85 1792.77 1758.64 1122.39 1599.76 1249.74 TRUE FALSE FALSE 1525.85591 1462.092362 1657.835152 1664.792907 1555.082867 1420.929293 1807.982705 1464.601544 1424.27033 1293.168372 1.179935995 1.130627994 1.281994818 1.287375212 1.20253704 1.098796819 1.398103097 1.132568331 1.101380424 1 10.33669441 -8.84483737 0.429053916 0.961654906 1.237205533 0.342484344 0.08877263 0.941564711 0.291994685 0.113896718 0.027661587 1.43E-09 8.84483737 0.275550628 SRTS(ph)VQT(ph)EDDQLIAGQSAR ddPTM_HeLa_Curcumin_4h_R1 2 SRTSVQTEDDQLIAGQSAR 19 1 G3XAM7;P35221-3;P35221;P35221-2;A0A0A0MTJ6;A0A0A0MRI5;P26232-4;P26232-6;P26232-3;P26232-2;P26232-5;P26232 G3XAM7 CTNNA1;CTNNA2 Catenin alpha-1;Catenin alpha-2 2 0 S(0.024)RT(0.121)S(0.855)VQT(1)EDDQLIAGQSAR;S(0.022)RT(0.203)S(0.775)VQT(0.995)EDDQLIAGQS(0.005)AR ; 133.95 0.00076039 11871300 4433.9 4443.8 4587.8 5251 4712.4 6151.4 3117.7 1490.3 5473.5 4830.6 TRUE FALSE FALSE 4082.952136 4827.902271 4757.827904 5229.272753 4656.207708 4875.530299 3205.174271 1944.68561 4873.070744 4998.46299 0.816841526 0.965877367 0.951858184 1.046176147 0.931527895 0.975405902 0.64123197 0.389056719 0.974913839 1 12.28726882 -4.530475921 2.757356498 0.932587209 0.394901431 0.894527112 0.062990879 0.087436531 1.200449395 0.011555275 0.07997976 2.95E-05 4.530475921 -0.537685778 down GS(ph)KSPDLLMYQGPPDTAEIIK ddPTM_HeLa_Curcumin_4h_R1 2 GSKSPDLLMYQGPPDTAEIIK 21 1 P82909 P82909 MRPS36 "28S ribosomal protein S36, mitochondrial" 1 0 GS(0.634)KS(0.366)PDLLMYQGPPDTAEIIK;GS(0.584)KS(0.415)PDLLMY(0.001)QGPPDTAEIIK ; 148.72 5.97E-06 60545000 3417.5 3349.6 3592.7 4019 3426.4 4878.8 3054.15 2630.8 4290.1 3521.7 TRUE FALSE FALSE 3147.001269 3639.124498 3725.848622 4002.370443 3385.542418 3866.881885 3139.841229 3432.918809 3819.486763 3644.078813 0.863593086 0.998640448 1.022439089 1.098321592 0.929053018 1.061141123 0.861628244 0.942053942 1.048135059 1 11.83133845 -4.698350331 24.99999988 0.962893571 0.901841372 0.060870919 0.074632402 134.9196081 53460.90446 0.011354 0.042482764 2.00E-05 4.698350331 -0.061052198 GS(ph)LAS(ph)LDSLR ddPTM_HeLa_Curcumin_4h_R1 1 GSLASLDSLR 10 0 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12;O60716-25;O60716-26;O60716-27;O60716-29;O60716-32;O60716-28;O60716-31;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 2 0 GS(0.999)LAS(0.949)LDS(0.053)LR 110.64 0.017501 8743400 3539.4 3484.4 3717 3085.6 3920 4516.8 2871.7 4055.5 4359.6 3116.9 TRUE FALSE FALSE 3259.252755 3785.57601 3854.75529 3072.832605 3873.25656 3579.964765 2952.272173 5292.003281 3881.362787 3225.212043 1.010554566 1.173744845 1.195194374 0.952753668 1.200930825 1.109993612 0.915373046 1.640823366 1.203444219 1 11.6551783 -4.254031266 24.95246345 1.041109509 1.640823657 0.677800377 0.11145167 320.4788978 1079430.016 0.013963886 0.193660456 5.57E-05 4.254031266 0.599714148 GS(ph)LASLDSLR ddPTM_HeLa_Curcumin_4h_R1 2 GSLASLDSLR 10 0 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12;O60716-25;O60716-26;O60716-27;O60716-29;O60716-32;O60716-28;O60716-31;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 0 GS(0.791)LAS(0.209)LDSLR;GS(0.768)LAS(0.232)LDSLR ; 160.72 0.00061062 6488460 3003.6 3060.61 2823.7 2235.55 2967.9 3923.9 2702.5 2904.87 3253.8 2689.4 TRUE FALSE FALSE 2765.861891 3325.155491 2928.348806 2226.299886 2932.509731 3110.038909 2778.324877 3790.551491 2896.866281 2782.85645 0.993893124 1.194871367 1.052281661 0.800005292 1.05377686 1.117570728 0.998371611 1.362108164 1.040968635 1 11.44235078 GS(ph)LCMS(ph)S(ph)GIKTPK ddPTM_HeLa_Curcumin_4h_R1 1 GSLCMSSGIKTPK 13 1 P08F94-2;P08F94 P08F94-2 PKHD1 Fibrocystin 3 0 GS(0.999)LCMS(0.998)S(0.985)GIKT(0.018)PK 40.857 0.019018 16372000 3742.9 2882 3763.2 3571.4 4373.4 4210.8 3488.2 2199.4 3755.3 2696.5 TRUE FALSE FALSE 3446.645516 3131.107238 3902.667502 3556.622493 4321.250061 3337.432615 3586.069504 2869.986935 3343.352985 2790.203174 1.235266861 1.122178939 1.3987037 1.274682262 1.548722366 1.196125302 1.285235977 1.028594248 1.198247144 1 11.44615446 -8.798269794 0.563321864 0.98381377 1.282107469 0.116618902 0.146317427 0.799970414 0.459387591 0.118091453 0.034166324 1.59E-09 8.798269794 0.298293699 GS(ph)LDESSLGFGYPK ddPTM_HeLa_Curcumin_4h_R1 1 GSLDESSLGFGYPK 14 0 Q2KJU6;Q9BUZ4 Q2KJU6 TRAF4 TNF receptor-associated factor 4 1 0 GS(0.961)LDES(0.015)S(0.024)LGFGYPK 155.14 0.00039905 40748000 2214 2548 2594.1 2228.4 2567.3 3650.4 2251.6 1077.6 2506.9 2554.6 TRUE FALSE FALSE 2038.759564 2768.237766 2690.239628 2219.179471 2536.686624 2893.265892 2314.773836 1406.155279 2231.899342 2643.37216 0.771272239 1.047237241 1.017730181 0.83952593 0.959640365 1.094535963 0.875689724 0.531955092 0.844337916 1 11.36816384 -4.276144203 4.451967406 0.92359824 0.509694042 0.604342017 0.098713444 0.115891699 5.598704419 0.015937451 0.146153126 5.29E-05 4.276144203 -0.413904198 GS(ph)PATSPHLGR ddPTM_HeLa_Curcumin_4h_R1 2 GSPATSPHLGR 11 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 0 GS(0.999)PAT(0.001)SPHLGR;GS(0.999)PAT(0.001)SPHLGR ; 93.649 0.0070712 14278700 2464.52 2794.8 1995.49 2103.55 4322.1 4103.6 2710.1 879.61 2582.3 1721.91 TRUE FALSE FALSE 2269.450641 3036.370059 2069.444615 2094.846067 4270.56178 3252.467103 2786.138112 1147.79904 2299.028151 1781.746244 1.273722702 1.704154039 1.16146989 1.175726383 2.396840624 1.825437889 1.563712072 0.644198939 1.290322995 1 10.79907617 -7.83077141 0.675347531 1.033638098 1.54782443 0.071541114 0.447853779 0.819594745 0.838806526 0.159807518 0.125466627 1.48E-08 7.83077141 0.514186332 GS(ph)PDGSLQTGKPSAPK ddPTM_HeLa_Curcumin_4h_R1 1 GSPDGSLQTGKPSAPK 16 1 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 "Proline-, glutamic acid- and leucine-rich protein 1" 1 0 GS(0.991)PDGS(0.009)LQTGKPSAPK 115.56 0.011597 11227000 2563.4 1988.9 2362.9 2501.6 2668.5 2579.9 2158.9 1977.2 2527 1753.1 TRUE FALSE FALSE 2360.504185 2160.811654 2450.471153 2491.249042 2636.67988 2044.799659 2219.472924 2580.039178 2249.794422 1814.020095 1.301255809 1.191172942 1.350851162 1.373330455 1.453500922 1.12721996 1.22351066 1.422277066 1.240225744 1 10.82497472 -9.241480252 0.548900378 0.945202776 1.312085263 0.170751276 0.121347095 0.750730623 0.320606214 0.143861234 0.024076704 5.73E-10 9.241480252 0.366882488 GS(ph)PEEELPLPAFEK ddPTM_HeLa_Curcumin_4h_R1 2 GSPEEELPLPAFEK 14 0 Q5JTD0-4;Q5JTD0-2;Q5JTD0 Q5JTD0-4 TJAP1 Tight junction-associated protein 1 1 0 GS(1)PEEELPLPAFEK;GS(1)PEEELPLPAFEK ; 229.23 2.04E-20 118224000 8029.9 6464.9 7599.8 6476.7 7741.7 8399.8 7453.1 9516.2 6702 6366.5 TRUE FALSE FALSE 7394.324942 7023.697149 7881.455273 6449.901132 7649.385284 6657.586795 7662.213927 12417.64557 5966.807368 6587.735401 1.12243806 1.066177787 1.196383096 0.979077139 1.161155514 1.010603248 1.163102866 1.884964228 0.905744843 1 12.68556689 -4.263082258 3.645572636 1.068842082 1.974423146 0.896243554 0.084070844 0.049431554 1.195562084 0.00948461 0.12094296 5.46E-05 4.263082258 0.905581063 GS(ph)PETNHLIR ddPTM_HeLa_Curcumin_4h_R1 2 GSPETNHLIR 10 0 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 0 GS(1)PETNHLIR;GS(1)PETNHLIR ; 145.14 0.00054555 52657000 3229.8 3189.7 3276.5 3256.7 2876.1 4621.7 4549.4 1517.54 3840.5 2989.9 TRUE FALSE FALSE 2974.157922 3465.403455 3397.929972 3243.224638 2841.804386 3663.107323 4677.04392 1980.23096 3419.206758 3093.798802 0.96132881 1.12011274 1.098303474 1.048298498 0.918548544 1.184016013 1.511747925 0.640064557 1.10518071 1 11.59516366 -7.264910297 24.01686997 0.981738604 1.089391912 0 0.209074317 401.3774884 2777310.145 0.032261223 0.037701186 5.43E-08 7.264910297 0.107653308 GS(ph)PGGYLGAK ddPTM_HeLa_Curcumin_4h_R1 1 GSPGGYLGAK 10 0 O60551 O60551 NMT2 Glycylpeptide N-tetradecanoyltransferase 2 1 0 GS(1)PGGYLGAK 115.91 0.0052741 10307000 2639.8 2197.7 2656.5 2355.1 3064.3 2223.9 2264.1 1461.7 2337.6 2163.8 TRUE FALSE FALSE 2430.857044 2387.659395 2754.952227 2345.35522 3027.760224 1762.638071 2327.624552 1907.365601 2081.171128 2238.991889 1.085692653 1.066399305 1.230443147 1.04750501 1.352287268 0.787246296 1.039585969 0.851885891 0.92951258 1 11.12863359 -5.20616462 24.99998621 1.076476153 0.907574152 0.346192696 0.127772335 291.7236304 131941.8094 0.016504637 0.042078703 6.22E-06 5.20616462 -0.168902001 GS(ph)PHYFS(ph)PFRPY ddPTM_HeLa_Curcumin_4h_R1 1 GSPHYFSPFRPY 12 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 2 0 GS(1)PHY(0.012)FS(0.988)PFRPY 102.29 0.0058411 236340000 1084.1 1218.5 1087.1 1167.3 1228.2 1223 1093.3 533.25 1206.5 1080.6 TRUE FALSE FALSE 998.2923411 1323.82171 1127.388882 1162.470022 1213.554517 969.3360139 1123.975056 695.8354702 1074.149969 1118.15077 0.892806559 1.183938469 1.008261956 1.039636204 1.085322794 0.866909938 1.005208856 0.622309164 0.960648597 1 10.12689902 -4.258992016 24.65564504 0.980373704 0.622309009 0.616145143 0.088699389 104.9020689 1056740.748 0.012938276 0.116848699 5.51E-05 4.258992016 -0.358064695 GS(ph)PHYFSPFRPY ddPTM_HeLa_Curcumin_4h_R1 3 GSPHYFSPFRPY 12 1 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 0 GS(1)PHYFSPFRPY;GS(1)PHYFSPFRPY;GS(1)PHYFSPFRPY ;; 106.29 0.002921 441921500 3138.64 1812.78 2134.32 2249.87 2649.96 3623.61 2598.58 2294.44 2544.97 2137.63 TRUE FALSE FALSE 2890.213332 1969.468626 2213.419777 2240.560634 2618.360958 2872.032439 2671.489161 2994.004194 2265.793158 2211.912483 1.306658086 0.890391749 1.000681443 1.012951756 1.18375432 1.298438551 1.207773445 1.35358167 1.024359316 1 11.11107859 -5.483328516 4.701401499 1.106287028 1.275729394 0.419265367 0.116661432 0.252748723 12.96231893 0.021481738 0.047916414 3.29E-06 5.483328516 0.169442367 VDIEAPDVS(ph)LEGPEGK ddPTM_HeLa_Curcumin_4h_R1 2 VDIEAPDVSLEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VDIEAPDVS(1)LEGPEGK;VDIEAPDVS(1)LEGPEGK ; 172.42 8.82E-05 14873400 6680 4701.3 5375.1 6187.3 5497.4 7969.7 5708.6 10332.7 6009.1 4999 TRUE FALSE FALSE 6151.270951 5107.659423 5574.305934 6161.698592 5431.847095 6316.694383 5868.767952 13483.09266 5349.916764 5172.714878 1.189176496 0.987423344 1.077636418 1.191192389 1.050095979 1.221156498 1.134562428 2.60657952 1.034257037 1 12.33670596 -4.26055878 5.828897899 1.097104165 2.652399747 0.971198791 0.077942161 0.017508582 2.62928985 0.01216026 0.107342402 5.49E-05 4.26055878 1.555295582 up GS(ph)PNTASAEATLPR ddPTM_HeLa_Curcumin_4h_R1 2 GSPNTASAEATLPR 14 0 Q6PJG6-3;Q6PJG6 Q6PJG6-3 BRAT1 BRCA1-associated ATM activator 1 1 0 GS(0.954)PNT(0.012)ASAEAT(0.033)LPR;GS(0.96)PNT(0.036)AS(0.004)AEATLPR ; 130.47 0.0010766 174238000 970.72 789.97 1033.17 1059.92 912.76 1071.5 828.79 581.1 943.04 1295.48 TRUE FALSE FALSE 893.8864877 858.2514868 1071.460189 1055.534332 901.8759331 849.2588217 852.0436168 758.2747149 839.5908714 1340.497834 0.666831729 0.640248321 0.799300202 0.787419648 0.672791787 0.633539869 0.635617302 0.565666498 0.62632766 1 10.38855317 -13.52287875 0.218176202 2.732045119 0.626334534 0 0.136257064 17.16352649 0.216681036 12.65350927 0.058770733 3.00E-14 13.52287875 -2.105710585 GS(ph)PQQIDHAK ddPTM_HeLa_Curcumin_4h_R1 2 GSPQQIDHAK 10 0 A0A087WTP3;Q92945;M0R3J3 A0A087WTP3 KHSRP Far upstream element-binding protein 2 1 0 GS(1)PQQIDHAK;GS(1)PQQIDHAK ; 135.04 0.0010426 67308000 11120.9 9373.3 9137.8 9633.1 10871.1 14442.2 10274 8646 9406 8906.6 TRUE FALSE FALSE 10240.66903 10183.48629 9476.454906 9593.240785 10741.46923 11446.72492 10562.26079 11282.1256 8374.185333 9216.103687 1.111171204 1.104966549 1.028249597 1.040921534 1.165510892 1.242035171 1.146065751 1.224175203 0.90864704 1 13.16994123 -1 0.128193432 0.975861838 1.776502191 0.630093048 0.060002893 45.71379933 0.396676014 0.196687068 6.626570819 0.1 1 0.800640352 GS(ph)PSGGS(ph)TAEASDTLSIR ddPTM_HeLa_Curcumin_4h_R1 2 GSPSGGSTAEASDTLSIR 18 0 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 2 0 GS(0.998)PS(0.005)GGS(0.608)T(0.361)AEAS(0.022)DT(0.004)LSIR;GS(1)PS(0.001)GGS(0.567)T(0.402)AEAS(0.001)DT(0.03)LSIR ; 139.78 0.0007447 9811300 3543.1 2495.2 3369.7 3198.9 3768 3856.4 2960.5 2905.1 3459.1 2766.5 TRUE FALSE FALSE 3262.659896 2710.87397 3494.584046 3185.663799 3723.069061 3056.539169 3043.563662 3790.851617 3079.645384 2862.635669 1.139739832 0.946985325 1.220757529 1.112842907 1.300573839 1.067736004 1.06320329 1.324252212 1.075807661 1 11.48312835 -13.52287874 0.095979619 0.50791327 1.266870137 0.213981222 0.103730997 132.6581567 0.956073539 13.30137273 0.977030764 3.00E-14 13.52287874 0.758956867 GS(ph)PSGGSTAEASDTLSIR ddPTM_HeLa_Curcumin_4h_R1 3 GSPSGGSTAEASDTLSIR 18 0 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 1 0 GS(0.933)PS(0.024)GGS(0.024)T(0.018)AEASDTLSIR;GS(0.995)PS(0.005)GGSTAEASDTLSIR;GS(0.818)PS(0.182)GGSTAEASDTLSIR ;; 214.54 6.83E-17 30877300 3316.09 2778.89 3042.96 2782.1 3014.16 3296.45 3574.77 4316.8 3298.43 2931.8 TRUE FALSE FALSE 3053.617977 3019.084869 3155.734774 2770.588407 2978.218111 2612.729111 3675.068425 5632.972448 2936.600481 3033.679832 1.006572264 0.995189023 1.040233297 0.91327647 0.981718004 0.861240888 1.211422638 1.85681178 0.967999474 1 11.56685312 -4.307649391 2.870612681 0.990031581 1.96398663 0.959835582 0.054481154 0.045160386 0.54861767 0.007187699 0.09631526 4.92E-05 4.307649391 0.973955049 GS(ph)PSPAAPGPPAGPLPR ddPTM_HeLa_Curcumin_4h_R1 1 GSPSPAAPGPPAGPLPR 17 0 Q6F5E8-2;Q6F5E8 Q6F5E8-2 RLTPR Leucine-rich repeat-containing protein 16C 1 0 GS(0.817)PS(0.183)PAAPGPPAGPLPR 83.856 0.0074372 4002800 665.65 701.27 762.24 617.86 430.82 727.54 409.78 558.95 697.3 528.96 TRUE FALSE FALSE 612.9631001 761.884654 790.4892849 615.303459 425.6827529 576.6400029 421.2773239 729.3712819 620.8079346 547.3413206 1.119891879 1.391973574 1.444234621 1.124167747 0.77772815 1.053529089 0.769679372 1.332571203 1.134224498 1 9.096296964 GS(ph)PSPASVSSGR ddPTM_HeLa_Curcumin_4h_R1 2 GSPSPASVSSGR 12 0 Q96II5;P10398 Q96II5 ARAF Serine/threonine-protein kinase A-Raf 1 0 GS(0.769)PS(0.221)PAS(0.001)VS(0.008)SGR;GS(0.997)PS(0.003)PASVSSGR ; 163.71 0.00012549 67238000 2822.5 2709.1 2826.6 2766.6 3436.4 2832.5 2237.39 843.29 2658.3 2245.7 TRUE FALSE FALSE 2599.096147 2943.262532 2931.356283 2755.152542 3395.423174 2245.007571 2300.165142 1100.405239 2366.691141 2323.737908 1.118497976 1.266606928 1.261483179 1.185655462 1.46119025 0.966119098 0.989855669 0.473549635 1.018484543 1 11.18223164 -4.146156648 1.771168323 1.120924794 0.118471978 0.669440676 0.143669891 0.661799808 1.618155864 0.022672085 1.215567872 7.14E-05 4.146156648 -1.002452816 GS(ph)PTGGAQLLK ddPTM_HeLa_Curcumin_4h_R1 2 GSPTGGAQLLK 11 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 0 GS(0.999)PT(0.001)GGAQLLK;GS(0.999)PT(0.001)GGAQLLK ; 145.81 0.00094784 149208000 7324.6 6871.4 7386.1 6529.4 7755.1 8241.3 6658.1 2258.44 6660.2 5448.4 TRUE FALSE FALSE 6744.850181 7465.333198 7659.835363 6502.383073 7662.625498 6531.961481 6844.908367 2947.027959 5929.592723 5637.731494 1.196376626 1.324173243 1.358673319 1.153368705 1.359168223 1.158615214 1.214124577 0.52273294 1.051769267 1 12.46089905 -4.258424203 24.58122316 1.159885801 0.522732643 0.729817112 0.121569121 112.3999963 916279.5626 0.020251243 0.19051692 5.52E-05 4.258424203 -0.637153159 LVNTTIT(ph)PEPEPKPQPNSR ddPTM_HeLa_Curcumin_4h_R1 1 LVNTTITPEPEPKPQPNSR 19 1 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 LVNTT(0.006)IT(0.994)PEPEPKPQPNSR 212.06 1.73E-14 62472000 1844.7 1829.3 1583.4 1692.6 1321.2 1544 982.1 507.95 2643.6 1999.1 TRUE FALSE FALSE 1698.690048 1987.416541 1642.082197 1685.59647 1305.445553 1223.756996 1009.655083 662.8216167 2353.603694 2068.568576 0.821191073 0.96076899 0.793825361 0.814861295 0.631086428 0.591596048 0.4880936 0.320425257 1.13779341 1 11.01441707 -4.529586068 0.401873692 0.944600763 1.90E-19 0.882218726 0.081251137 0.906374765 0.115249949 0.018033567 0.395015955 2.95E-05 4.529586068 -0.944600763 down GS(ph)PTSAYPER ddPTM_HeLa_Curcumin_4h_R1 1 GSPTSAYPER 10 0 J3KPS2;A0A494C1T9;Q6ZRV2 J3KPS2 FAM83H Protein FAM83H 1 0 GS(0.999)PT(0.001)SAYPER 116.84 0.0051144 64721000 1238 1206.6 1324 1660.1 1692.7 1560.6 1530.5 1015.8 1421.9 1292.6 TRUE FALSE FALSE 1140.010994 1310.893127 1373.068605 1653.230946 1672.515658 1236.913968 1573.441711 1325.512744 1265.921127 1337.517754 0.852333354 0.980094002 1.026579723 1.236044113 1.250462398 0.924783215 1.176389402 0.991024411 0.946470523 1 10.38534233 -6.659401994 2.975404235 0.930931417 1.11647438 0.383206847 0.101282336 0.19743828 3.529348422 0.017181939 0.024827947 2.19E-07 6.659401994 0.185542962 GS(ph)PVFLPR ddPTM_HeLa_Curcumin_4h_R1 2 GSPVFLPR 8 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 0 GS(1)PVFLPR;GS(1)PVFLPR ; 101.46 0.014198 21772400 3960.8 3846.5 3999.8 4371.8 4449.3 5575.9 4682 2675.49 4362.8 4716.2 TRUE FALSE FALSE 3647.298501 4178.97432 4148.036107 4353.71065 4396.245003 4419.395487 4813.364319 3491.234585 3884.211755 4880.087599 0.747383818 0.856331825 0.849992141 0.892137807 0.900853707 0.905597573 0.986327442 0.715404081 0.795930744 1 12.25269133 -9.627589078 1.464718304 0.999505411 0.847775279 0 0.096800122 0.382312406 1.481098522 0.055837754 0.012927153 2.36E-10 9.627589078 -0.151730131 GS(ph)S(ph)NFNAHKVIHT(ph)AEKPY(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 GSSNFNAHKVIHTAEKPYK 19 2 A6NN14 A6NN14 ZNF729 Zinc finger protein 729 4 0 GS(1)S(1)NFNAHKVIHT(1)AEKPY(1)K 42.059 0.019553 2792000 142.77 175.23 66.137 120.67 163.34 143.19 129.39 0 171.5 199.86 TRUE FALSE FALSE 131.4696038 190.3761004 68.5880954 120.1706995 161.3922772 113.4907799 133.0203352 0 152.6868791 206.8051201 0.635717354 0.920557964 0.331655693 0.581081839 0.78040755 0.548781287 0.64321587 0 0.738312857 1 7.692128094 -9.53319796 0.090350936 1.765684464 3.59E-17 0.349116448 0.220846459 30.60884123 0.648067434 9.343661413 3.942539293 2.93E-10 9.53319796 -1.765684464 GS(ph)SAAASPGSPPPGR ddPTM_HeLa_Curcumin_4h_R1 1 GSSAAASPGSPPPGR 15 0 Q86UX6 Q86UX6 STK32C Serine/threonine-protein kinase 32C 1 0 GS(0.69)S(0.014)AAAS(0.022)PGS(0.274)PPPGR 83.087 0.013312 11386000 3037.8 3003.8 2517.5 3252.2 2774.1 3141.3 2144.4 1808.7 3027.6 3117.2 TRUE FALSE FALSE 2797.354925 3263.435087 2610.800765 3238.743258 2741.020669 2489.75897 2204.566093 2360.164304 2695.479855 3225.522468 0.867256375 1.011753947 0.809419494 1.004098806 0.849791219 0.771893234 0.683475658 0.731715351 0.835672323 1 11.65531715 -2.658377368 0.289347994 0.962983182 4.78E-13 0.485828272 0.079188448 9.680477818 0.287423318 0.031103587 3.969766546 0.002195951 2.658377368 -0.962983182 GS(ph)SGSPAHAESYSSGGGGQQK ddPTM_HeLa_Curcumin_4h_R1 2 GSSGSPAHAESYSSGGGGQQK 21 0 P15408 P15408 FOSL2 Fos-related antigen 2 1 0 GS(0.361)S(0.361)GS(0.277)PAHAESYSSGGGGQQK;GS(0.333)S(0.333)GS(0.333)PAHAESYSSGGGGQQK ; 151.3 2.22E-06 41721000 13466.5 9845.9 7740.8 7848.6 16079.4 28841.5 13053.2 6623.1 15788.6 8667.2 TRUE FALSE FALSE 12400.61232 10696.93572 8027.680858 7816.124573 15887.66366 22859.44779 13419.43766 8642.452701 14056.63008 8968.384555 1.38270301 1.192738297 0.895108903 0.871519784 1.771519002 2.548892462 1.49630489 0.963657685 1.567353629 1 13.13063243 -5.74640841 24.71283496 1.14280422 1.741880195 0.289945983 0.41397021 190.4015411 313042.2614 0.059349022 0.118307605 1.79E-06 5.74640841 0.599075975 GS(ph)SPLPTATTPKPLIPTEASIR ddPTM_HeLa_Curcumin_4h_R1 1 GSSPLPTATTPKPLIPTEASIR 22 1 Q9BUK6-2;Q9BUK6;A0A3B3IUD2;Q9BUK6-7;Q9BUK6-3 Q9BUK6-2 MSTO1 Protein misato homolog 1 1 0 GS(0.391)S(0.354)PLPT(0.104)AT(0.128)T(0.023)PKPLIPTEASIR 65.581 0.0016459 44098000 977.63 819.82 965.27 1060.1 1013.3 1784.5 971.21 861.31 1005.8 909.37 TRUE FALSE FALSE 900.2495539 890.6815878 1001.043755 1055.713587 1001.217059 1414.374585 998.4595387 1123.919454 895.4662564 940.9705398 0.956724484 0.946556295 1.06384176 1.121941169 1.064025936 1.503101877 1.061095429 1.194425762 0.951641118 1 9.878005745 -6.04129044 1.367927664 0.977779362 1.225229692 0.482504379 0.113792655 0.257748326 0.95527331 0.017408493 0.037294036 9.09E-07 6.04129044 0.24745033 GS(ph)YGDLGGPIITTQVTIPK ddPTM_HeLa_Curcumin_4h_R1 2 GSYGDLGGPIITTQVTIPK 19 0 P61978-3;P61978;P61978-2;Q5T6W2;S4R359 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 0 GS(1)YGDLGGPIITTQVTIPK;GS(1)YGDLGGPIITTQVTIPK ; 296.45 1.49E-83 116167000 4760.6 4849.2 4666.9 4179.9 5215.8 18704.2 11846.2 6225.4 3970.5 3796.4 TRUE FALSE FALSE 4383.793487 5268.34324 4839.859419 4162.604681 5153.604992 14824.73808 12178.57249 8123.495802 3534.946084 3928.324617 1.115944815 1.34111708 1.232041618 1.059638672 1.311909145 3.773806781 3.100195039 2.067928848 0.899860991 1 11.93969844 -5.355244378 6.283680871 1.100246393 2.985843614 0.814838127 0.40309768 0.064602852 3.591720749 0.054453629 0.122983481 4.41E-06 5.355244378 1.885597221 GSALDDAVNPLHENGDDS(ph)LSPR ddPTM_HeLa_Curcumin_4h_R1 1 GSALDDAVNPLHENGDDSLSPR 22 0 Q9BVI0 Q9BVI0 PHF20 PHD finger protein 20 1 0 GSALDDAVNPLHENGDDS(0.5)LS(0.5)PR 120.38 4.38E-06 11116000 849.81 804.69 780.01 650.57 816.36 1236.9 941.69 994.91 924.79 693.6 TRUE FALSE FALSE 782.5466418 874.243818 808.9178568 647.8781137 806.6254402 980.3529973 968.111287 1298.253479 823.3428507 717.7025484 1.090349538 1.218114412 1.127093472 0.902711179 1.123899368 1.365960034 1.348903232 1.808901866 1.147192319 1 9.487242233 -1 0.577570499 1.048477212 42.37196718 0.825406588 0.100049936 37.22629716 0.285556573 0.017799796 1934.507123 0.1 1 41.32348997 GSALGTPAAAEPVT(ph)PTSK ddPTM_HeLa_Curcumin_4h_R1 1 GSALGTPAAAEPVTPTSK 18 0 P00519;P00519-2 P00519 ABL1 Tyrosine-protein kinase ABL1 1 0 GSALGTPAAAEPVT(0.889)PT(0.11)S(0.001)K 186.17 6.08E-07 8726100 4213.5 4247.4 4367.4 4112.4 4360 5474.7 4974.6 4553.9 4622.1 4201.6 TRUE FALSE FALSE 3879.997029 4614.52633 4529.259686 4095.383978 4308.009848 4339.185507 5114.173888 5942.363146 4115.067194 4347.605287 0.892444639 1.061394958 1.041782634 0.941986153 0.990892586 0.998063352 1.176319732 1.366812936 0.946513522 1 12.08600525 -4.432655315 1.545562059 0.964755016 1.449987693 0.863063703 0.048491062 0.228663906 0.644288751 0.008543395 0.151422229 3.69E-05 4.432655315 0.485232677 GSALGTPAAAEPVTPT(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 GSALGTPAAAEPVTPTSK 18 0 P00519;P00519-2 P00519 ABL1 Tyrosine-protein kinase ABL1 1 0 GSALGTPAAAEPVT(0.351)PT(0.635)S(0.014)K 111.34 0.0019822 12232000 2783.3 2619.8 2676 3035.5 2966.8 3724.3 3345.5 3039.6 3468.4 2613.9 TRUE FALSE FALSE 2562.998868 2846.243838 2775.174914 3022.939905 2931.422848 2951.838198 3439.365726 3966.360047 3087.925198 2704.73283 0.947597796 1.052319773 1.026044008 1.117648247 1.083812351 1.091360361 1.271610152 1.466451696 1.141674757 1 11.40127038 -1 0.441968656 0.979309343 11.63365429 0.798235901 0.06402219 13.25401047 0.145392441 0.009505083 127.9029152 0.1 1 10.65434495 GSAPHSESDLPEQEEEILGS(ph)DDDEQEDPNDYCK ddPTM_HeLa_Curcumin_4h_R1 2 GSAPHSESDLPEQEEEILGSDDDEQEDPNDYCK 33 0 D6RBM8;H3BLV9;Q96SB4-4;Q96SB4;Q96SB4-3 D6RBM8 SRPK1 SRSF protein kinase 1 1 0 GSAPHSESDLPEQEEEILGS(1)DDDEQEDPNDYCK;GSAPHSESDLPEQEEEILGS(1)DDDEQEDPNDYCK ; 132.16 5.72E-18 53119000 8655 6584.5 6639.4 6312.7 7579.9 10400.1 6799.5 6060.3 8529.6 6772.5 TRUE FALSE FALSE 7969.947617 7153.63484 6885.462005 6286.57972 7489.514643 8243.002027 6990.27567 7908.057572 7593.92422 7007.843871 1.137289552 1.020803969 0.982536445 0.897077594 1.068733091 1.176253664 0.997493066 1.128458013 1.08363205 1 12.77475492 -4.228203483 21.93016708 1.050755175 1.128458768 0.092192803 0.076956335 6002.180741 3960085.537 0.011781453 1.835210565 5.91E-05 4.228203483 0.077703593 GSAPPGPVPEGSIR ddPTM_HeLa_Curcumin_4h_R1 2 GSAPPGPVPEGSIR 14 0 P78417;P78417-2 P78417 GSTO1 Glutathione S-transferase omega-1 0 0 ; ; 158.06 0.00059268 8813800 856.66 521.08 512.21 658.17 757.06 813.09 771.5 724.93 793.06 725.54 FALSE FALSE TRUE 788.8544571 566.1198333 531.1929532 655.4466669 748.032554 644.4459686 793.1462136 945.9578198 706.0633021 750.752461 1.050751743 0.7540699 0.707547402 0.873052971 0.996377092 0.858400075 1.05646835 1.260012946 0.940474176 1 9.552193489 -4.358396772 3.257070982 0.960803974 1.274193726 0.41172974 0.117281053 0.266047258 4.497035575 0.019308957 0.179023687 4.38E-05 4.358396772 0.313389752 GSASYS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 2 GSASYSPPR 9 0 A0A087WTY1;P0DPB5 A0A087WTY1 POLR1D 1 0 GSAS(0.013)YS(0.987)PPR;GSAS(0.012)YS(0.988)PPR ; 96.143 0.015391 295570000 5334 4302.9 4497.1 4710.4 5274.7 5938 4619.6 3278.3 5801.3 4528.3 TRUE FALSE FALSE 4911.808272 4674.823503 4663.766482 4690.909613 5211.802648 4706.391865 4749.213543 4277.838579 5164.911904 4685.658088 1.048264338 0.997687713 0.995327955 1.001120766 1.112288295 1.004424945 1.013563827 0.912964305 1.102281005 1 12.19403597 -4.219272327 2.906930557 1.023180457 0.887201309 0.405476789 0.04200309 0.344458229 3.714422021 0.004845442 0.114466415 6.04E-05 4.219272327 -0.135979148 GSAVHQLSEELR ddPTM_HeLa_Curcumin_4h_R1 1 GSAVHQLSEELR 12 0 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 0 0 137.01 0.0005692 0 2316 1881.1 1550.8 1778 2422.6 3531.2 1877.8 884.18 2773.6 1956.4 FALSE FALSE TRUE 2132.686156 2043.693902 1608.274012 1770.643107 2393.712077 2798.789315 1930.486014 1153.762412 2469.343019 2024.384754 1.053498428 1.009538279 0.794450763 0.874657401 1.182439293 1.38253823 0.953616159 0.569932375 1.219799257 1 10.9832678 -4.289999186 4.46728698 1.031605647 0.548832592 0.44132273 0.163037994 0.127192569 5.877315248 0.02158972 0.179144585 5.13E-05 4.289999186 -0.482773055 GSDALS(ph)ETS(ph)S(ph)VSHIEDLEK ddPTM_HeLa_Curcumin_4h_R1 1 GSDALSETSSVSHIEDLEK 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 3 0 GS(0.094)DALS(0.742)ET(0.501)S(0.787)S(0.768)VS(0.107)HIEDLEK 47.05 0.018723 4143400 2593.7 1973.7 2247.6 2181.7 2536.3 2004.4 1081.5 3671.2 2247.2 2011.4 TRUE FALSE FALSE 2388.405908 2144.297833 2330.898033 2172.672703 2506.056279 1588.664846 1111.843979 4790.53198 2000.687782 2081.296 1.147557055 1.030270482 1.119926254 1.043903752 1.204084512 0.763305578 0.534207522 2.301706235 0.961270181 1 11.02326644 -4.24702809 24.94592573 1.031743535 2.301707135 0.804578884 0.194065903 844.930668 1462549.957 0.026912979 0.782810797 5.66E-05 4.24702809 1.2699636 GSDALS(ph)ETSSVSHIEDLEK ddPTM_HeLa_Curcumin_4h_R1 1 GSDALSETSSVSHIEDLEK 19 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 0 GS(0.022)DALS(0.413)ET(0.413)S(0.121)S(0.03)VS(0.001)HIEDLEK 84.327 0.0016158 30556000 4772.6 3989.9 3656.8 3214.7 6220.5 5433.4 2135.6 801.22 5214 3738.4 TRUE FALSE FALSE 4394.843674 4334.769177 3792.324225 3201.398423 6146.3246 4306.451593 2195.519188 1045.50829 4642.037245 3868.309122 1.136114911 1.120585 0.980357077 0.827596328 1.588891789 1.113264596 0.5675656 0.270275269 1.200017139 1 11.91748737 -4.625928466 3.480916819 1.086899103 0.321509342 0.692544219 0.190350482 0.096468959 2.182053243 0.025978034 0.122420115 2.37E-05 4.625928466 -0.765389761 GSDALS(ph)ETSSVSHIEDLEKVER ddPTM_HeLa_Curcumin_4h_R1 1 GSDALSETSSVSHIEDLEKVER 22 1 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 0 GS(0.015)DALS(0.774)ET(0.203)S(0.008)SVSHIEDLEKVER 103.94 1.89E-05 8455100 3468.6 2456.9 2089.8 2602 2565.9 3478.2 1697.5 743.64 5171.9 3063.9 TRUE FALSE FALSE 3194.05665 2669.263488 2167.249826 2591.233613 2535.303318 2756.782113 1745.127281 970.3724127 4604.555509 3170.370297 1.007471163 0.841940606 0.683595171 0.817328378 0.799686813 0.86954578 0.550449038 0.306075418 1.452371514 1 11.63043564 -4.246546434 0.376694643 1.007450806 9.10E-19 0.614976293 0.178174788 2.289063505 0.221030619 0.034898038 1.044952816 5.67E-05 4.246546434 -1.007450806 GSDALSET(ph)S(ph)SVSHIEDLEKVER ddPTM_HeLa_Curcumin_4h_R1 1 GSDALSETSSVSHIEDLEKVER 22 1 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 2 0 GS(0.017)DALS(0.213)ET(0.571)S(0.571)S(0.571)VS(0.057)HIEDLEKVER 49.655 0.012715 4780000 2939.6 2078.5 2081 3207.1 2552.3 2714.8 1676.4 570.92 3527.9 3436 TRUE FALSE FALSE 2706.927558 2258.156278 2158.123691 3193.82987 2521.865489 2151.719878 1723.435272 744.9908798 3140.898196 3555.400744 0.761356526 0.635134107 0.606998717 0.898303764 0.709305553 0.605197566 0.484737276 0.209537808 0.883416082 1 11.79579647 -4.752156655 0.195755631 1.025465534 2.59E-23 0.67076024 0.12456865 5.698276211 0.248205602 0.201620302 1.476153698 1.77E-05 4.752156655 -1.025465534 S(ph)PGPPALKHPATK ddPTM_HeLa_Curcumin_4h_R1 1 SPGPPALKHPATK 13 1 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 0 S(1)PGPPALKHPATK 92.264 0.004813 61246000 3238.3 2406.4 2178.5 2558.4 2049.2 2302.1 1561.7 514.18 3151 2475.8 TRUE FALSE FALSE 2981.985138 2614.398493 2259.237126 2547.814019 2024.764628 1824.61851 1605.517099 670.951115 2805.343183 2561.833866 1.164004106 1.020518359 0.881882762 0.994527418 0.790357507 0.712231396 0.626706173 0.261902664 1.095052736 1 11.3229612 -4.529196049 0.580183266 1.073245153 3.17E-16 0.913386607 0.075041929 0.636906942 0.174897012 0.016987852 0.429535432 2.96E-05 4.529196049 -1.073245153 down GSDALSET(ph)SSVSHIEDLEKVER ddPTM_HeLa_Curcumin_4h_R1 2 GSDALSETSSVSHIEDLEKVER 22 1 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 0 GS(0.008)DALS(0.112)ET(0.468)S(0.194)S(0.194)VS(0.023)HIEDLEKVER;GS(0.001)DALS(0.123)ET(0.676)S(0.154)S(0.046)VSHIEDLEKVER ; 102.46 5.12E-05 10595900 4231.93 4007.01 3614.5 4510.65 3724.48 6462.38 3556.18 1660.1 6083.76 4830.13 TRUE FALSE FALSE 3896.968275 4353.35809 3748.45655 4491.986125 3680.068009 5122.009542 3655.95684 2166.256848 5416.386749 4997.976658 0.779709179 0.871024094 0.749994809 0.898760925 0.736311564 1.024816619 0.731487378 0.433426764 1.083715895 1 12.28712845 -13.52287873 0.033375227 2.18712695 3.78E-10 0.406666749 0.138288628 906.7412366 2.425687728 126.4257974 49.37438241 3.00E-14 13.52287873 -2.187126949 GSDASWKNDQEPPPEALDFS(ph)DDEKEK ddPTM_HeLa_Curcumin_4h_R1 3 GSDASWKNDQEPPPEALDFSDDEKEK 26 2 Q96HR8-2;Q96HR8 Q96HR8-2 NAF1 H/ACA ribonucleoprotein complex non-core subunit NAF1 1 0 GSDASWKNDQEPPPEALDFS(1)DDEKEK;GSDASWKNDQEPPPEALDFS(1)DDEKEK;GSDASWKNDQEPPPEALDFS(1)DDEKEK ;; 99.641 1.05E-06 65623800 12092.2 9042.7 9855.8 11050.1 8553.7 12420.2 9522.4 9123 13905.3 11648.1 TRUE FALSE FALSE 11135.08961 9824.310695 10221.06462 11004.37761 8451.702714 9844.110515 9789.572916 11904.5607 12379.92338 12052.87061 0.923853742 0.815101316 0.848019111 0.913008857 0.70121907 0.816744063 0.812219199 0.987695055 1.027134845 1 13.55708917 -7.721618169 0.893934202 0.984409796 0.833974203 0.446726894 0.072974318 0.333743609 0.565344663 0.018790765 0.01715242 1.90E-08 7.721618169 -0.150435593 GSDASWKNDQEPPPEALDFS(ph)DDEKEKEAK ddPTM_HeLa_Curcumin_4h_R1 1 GSDASWKNDQEPPPEALDFSDDEKEKEAK 29 3 Q96HR8-2;Q96HR8 Q96HR8-2 NAF1 H/ACA ribonucleoprotein complex non-core subunit NAF1 1 0 GSDASWKNDQEPPPEALDFS(1)DDEKEKEAK 59.687 0.0011366 7481900 2729.3 2162.5 1951.9 2511.6 1591.1 2471.9 1697 1931.8 3123.6 2464.3 TRUE FALSE FALSE 2513.273025 2349.416864 2024.239131 2501.207665 1572.127172 1959.200076 1744.613253 2520.796927 2780.948895 2549.934242 0.985622682 0.921363706 0.793839738 0.980891046 0.616536358 0.768333569 0.684179703 0.988573307 1.090596318 1 11.31624433 -6.728786769 1.031283201 0.997148576 0.776500431 0.430089393 0.112264906 0.316961293 0.673036513 0.019354025 0.030541724 1.87E-07 6.728786769 -0.220648144 GGASS(ph)SCCEEEQTQGR ddPTM_HeLa_Curcumin_4h_R1 2 GGASSSCCEEEQTQGR 16 0 Q9UJK0 Q9UJK0 TSR3 Ribosome biogenesis protein TSR3 homolog 1 0 GGAS(0.005)S(0.971)S(0.024)CCEEEQTQGR;GGAS(0.001)S(0.954)S(0.045)CCEEEQTQGR ; 203.05 2.77E-10 15012000 3840.2 3893.4 3997.4 4083.6 3729.6 4943.2 2672.1 1404.64 5392.8 4002.8 TRUE FALSE FALSE 3536.244118 4229.928147 4145.54716 4066.703145 3685.126956 3917.924599 2747.071934 1832.90827 4801.223332 4141.897002 0.853774035 1.021253823 1.000881277 0.981845551 0.889719603 0.945925163 0.66324004 0.442528694 1.159184627 1 12.01607596 -4.529018604 2.165807337 0.944177729 0.419773728 0.806171275 0.085626675 0.104786291 0.794378352 0.009484403 0.085030393 2.96E-05 4.529018604 -0.524404001 down GSDDAPYS(ph)PTAR ddPTM_HeLa_Curcumin_4h_R1 1 GSDDAPYSPTAR 12 0 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 0 GSDDAPYS(0.597)PT(0.403)AR 166.62 0.00012315 19638000 4190.2 3854.2 3666.8 4514.2 4033.1 4336.1 3101.2 1772 4714.3 3520.7 TRUE FALSE FALSE 3858.541249 4187.339874 3802.694834 4495.521437 3985.007917 3436.743982 3188.211326 2312.274643 4197.153085 3643.044063 1.059153055 1.14940687 1.043823453 1.23400139 1.093867614 0.943371511 0.875150361 0.634709491 1.152100554 1 11.83092873 -4.40264392 1.452172417 1.057178279 0.54048387 0.775957218 0.076795269 0.35242365 0.810849677 0.01163009 0.242292107 3.96E-05 4.40264392 -0.516694408 GSDDAPYSPT(ph)AR ddPTM_HeLa_Curcumin_4h_R1 1 GSDDAPYSPTAR 12 0 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 0 GSDDAPYS(0.014)PT(0.986)AR 119.17 0.010583 17615000 3874.8 4283.5 3651.3 3771.3 3527.3 3364.4 2710.3 1355.7 3731.8 3260.6 TRUE FALSE FALSE 3568.105491 4653.746653 3786.62039 3755.69536 3485.239251 2666.585515 2786.343724 1769.046689 3322.430877 3373.905607 1.057559371 1.379335167 1.122325527 1.113159583 1.032998447 0.790355696 0.82585112 0.524332004 0.984743281 1 11.7202039 -4.654450497 1.090291543 1.070752277 0.483104643 0.704576949 0.118330694 0.470009149 0.675956978 0.019484186 0.26956172 2.22E-05 4.654450497 -0.587647634 GSDFDCELR ddPTM_HeLa_Curcumin_4h_R1 3 GSDFDCELR 9 0 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 0 ;; ;; 185.72 0.0010418 268846000 13616.5 10889.2 11624.7 12516.4 11571.8 14640.5 11781.3 11189.8 13263.3 11812.4 FALSE FALSE TRUE 12538.73966 11830.41393 12055.52161 12464.61045 11433.81384 11603.89527 12111.85157 14601.51851 11808.34917 12222.88002 1.02584167 0.967890866 0.986307776 1.01977688 0.935443514 0.949358518 0.990916343 1.194605403 0.966085665 1 13.57729664 -4.26020401 24.90989312 0.997883487 1.194605469 0.799674072 0.031003356 37.43548085 754751.9561 0.004635278 0.038633431 5.49E-05 4.26020401 0.196721982 GSDIDNPTLTVMDIS(ph)PPS(ph)RSPR ddPTM_HeLa_Curcumin_4h_R1 2 GSDIDNPTLTVMDISPPSRSPR 22 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 2 0 GSDIDNPTLTVMDIS(0.996)PPS(0.584)RS(0.42)PR;GSDIDNPTLT(0.001)VMDIS(0.989)PPS(0.665)RS(0.345)PR ; 79.67 0.0015689 26323200 6427.5 5461.7 5326.5 5642.6 5533.1 6189.7 3854.2 3778.5 7106.2 6215.9 TRUE FALSE FALSE 5918.756593 5933.785011 5523.904776 5619.252416 5467.121396 4905.886448 3962.338479 4930.547256 6326.667639 6431.902062 0.920218706 0.922555249 0.858829118 0.873653293 0.850000722 0.762742716 0.616044592 0.766576855 0.983638678 1 12.65102972 -4.866543511 0.305487802 0.992778047 0.512042996 0.812027938 0.047534514 1.514192472 0.137565694 0.022587955 0.259511393 1.36E-05 4.866543511 -0.48073505 GSDIDNPTLTVMDIS(ph)PPSR ddPTM_HeLa_Curcumin_4h_R1 4 GSDIDNPTLTVMDISPPSR 19 0 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 0 GSDIDNPTLT(0.001)VMDIS(0.909)PPS(0.089)R;GSDIDNPT(0.001)LT(0.482)VMDIS(0.509)PPS(0.008)R;GSDIDNPTLT(0.002)VMDIS(0.996)PPS(0.002)R;GSDIDNPTLTVMDIS(0.997)PPS(0.003)R ;;; 133.95 4.48E-05 16736200 4774.9 4475.15 4447.46 4327.13 4629.77 7587.1 6752.3 6460.4 5063.3 4484.1 TRUE FALSE FALSE 4396.961627 4861.962025 4612.28678 4309.225483 4574.563017 6013.449936 6941.751365 8430.14622 4507.868658 4639.922141 0.947636941 1.047854226 0.994044003 0.928727972 0.985913745 1.296023888 1.496092209 1.816872345 0.97153972 1 12.17988488 -4.681133851 1.276623156 0.975712134 1.892756951 0.972825426 0.046384438 0.080688163 0.180312376 0.007142809 0.079081491 2.08E-05 4.681133851 0.917044818 GSDIDNPTLTVMDIS(ph)PPSRS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 GSDIDNPTLTVMDISPPSRSPR 22 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 2 0 GSDIDNPTLTVMDIS(1)PPS(0.37)RS(0.63)PR 114.03 8.81E-06 16322000 3835.6 3160.3 2923.2 2845.7 2932.4 3315 1854.3 1585 3403.8 3188.1 TRUE FALSE FALSE 3532.008213 3433.46225 3031.536364 2833.925247 2897.433045 2627.431632 1906.326667 2068.259204 3030.411656 3298.886238 1.070666873 1.040794378 0.918957534 0.859055161 0.878306445 0.796460212 0.577869781 0.626956813 0.918616599 1 11.68776331 -5.163426014 0.63769433 1.035351512 0.507949812 0.845487469 0.061033959 0.301828751 0.155932019 0.010301877 0.09379641 6.86E-06 5.163426014 -0.5274017 QLS(ph)GQSTSSDTTYK ddPTM_HeLa_Curcumin_4h_R1 1 QLSGQSTSSDTTYK 14 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 0 QLS(0.694)GQS(0.149)T(0.149)S(0.006)S(0.002)DTTYK 156.29 7.06E-07 0 2904 2506.5 2491.1 2515.1 2623.2 2888 1604.5 736.86 2846.9 2266 TRUE FALSE FALSE 2674.145336 2723.150691 2583.422357 2504.693183 2591.920053 2288.996246 1649.517952 961.5252219 2534.602193 2344.743331 1.140485315 1.161385408 1.101793242 1.068216358 1.10541739 0.976224653 0.703496169 0.410076962 1.08097213 1 11.19521429 -4.525164297 1.626905836 1.08112447 0.330865995 0.962598658 0.043614931 0.114385939 0.413954511 0.009096402 0.114762675 2.98E-05 4.525164297 -0.750258475 down GSDS(ph)DSEGDNPEK ddPTM_HeLa_Curcumin_4h_R1 1 GSDSDSEGDNPEK 13 0 I3L4J1;Q9UN37 I3L4J1 VPS4A Vacuolar protein sorting-associated protein 4A 1 0 GSDS(0.994)DS(0.006)EGDNPEK 269.88 5.77E-47 58167000 4401.7 4308.2 5264.6 4152 5027.2 4711.7 3265.2 2689.4 3612.4 3367.8 TRUE FALSE FALSE 4053.3008 4680.581611 5459.710707 4134.820124 4967.253923 3734.440308 3356.812724 3509.38568 3216.128758 3484.830799 1.163127002 1.343130235 1.566707545 1.186519622 1.425393142 1.07162744 0.963264192 1.007046219 0.922893805 1 11.76687289 -3.036785419 14.00162278 1.143499894 1.135012568 0 0.206442763 0 0 0.02847466 0 0.000918786 3.036785419 -0.008487327 GSDS(ph)DSEGDNPEKK ddPTM_HeLa_Curcumin_4h_R1 2 GSDSDSEGDNPEKK 14 1 I3L4J1;Q9UN37 I3L4J1 VPS4A Vacuolar protein sorting-associated protein 4A 1 0 GS(0.047)DS(0.82)DS(0.133)EGDNPEKK;GS(0.171)DS(0.824)DS(0.004)EGDNPEKK ; 152.07 0.00072661 44762000 4359 4546.1 4437.4 2935.98 3801.46 3844.4 2915.93 2839.19 3300.74 3878.56 TRUE FALSE FALSE 4013.98055 4939.044627 4601.853948 2923.831693 3756.130072 3047.028105 2997.743148 3704.845961 2938.65708 4013.339671 1.000159687 1.230657017 1.146639538 0.728528341 0.935911331 0.759225073 0.746944788 0.923132918 0.732222369 1 11.97058755 -6.257149504 24.99850547 1.031032297 0.817961585 0.356090007 0.136339064 236.9521999 1380796.376 0.015681241 0.025424907 5.53E-07 6.257149504 -0.213070712 GSDSDS(ph)EGDNPEK ddPTM_HeLa_Curcumin_4h_R1 1 GSDSDSEGDNPEK 13 0 I3L4J1;Q9UN37 I3L4J1 VPS4A Vacuolar protein sorting-associated protein 4A 1 0 GSDS(0.364)DS(0.636)EGDNPEK 210.07 2.14E-09 44274000 2994.1 3235.8 3475.1 3028.4 3605.3 2961.5 2658 1734 2626.5 2455.1 TRUE FALSE FALSE 2757.113826 3515.488134 3603.890263 3015.869283 3562.309152 2347.251517 2732.576326 2262.688618 2338.379521 2540.414542 1.085300757 1.383824598 1.418622907 1.187156361 1.402255062 0.923963974 1.075641901 0.890676927 0.920471633 1 11.31084822 -3.117476194 14.06165174 1.10583245 1.105398902 0 0.198961717 0 0 0.026901798 0 0.000762999 3.117476194 -0.000433548 GSDYSWSYQT(ph)PPS(ph)SPSSSSSR ddPTM_HeLa_Curcumin_4h_R1 1 GSDYSWSYQTPPSSPSSSSSR 21 0 Q765P7;A0A087WXN9;H3BPV0 Q765P7 MTSS1L MTSS1-like protein 2 0 GS(0.002)DYS(0.015)WS(0.13)Y(0.054)QT(0.796)PPS(0.393)S(0.385)PS(0.152)S(0.031)S(0.013)S(0.015)S(0.014)R 54.875 0.018732 5919800 642.33 622.8 657.12 750.33 710.31 745.13 797.03 457.88 832.22 873.71 TRUE FALSE FALSE 591.4889027 676.6320569 681.4734453 747.2253333 701.8400172 590.5816387 819.3925167 597.4855042 740.9275481 904.0713575 0.65425024 0.748427711 0.753782807 0.826511455 0.776310422 0.653246709 0.906336109 0.660883125 0.819545429 1 9.820292837 -9.43534302 1.135212137 1.001684343 0.744468174 0.256215454 0.092827985 0.262693672 0.599198611 0.053756856 0.013103478 3.67E-10 9.43534302 -0.257216168 SGDET(ph)PGSEVPGDK ddPTM_HeLa_Curcumin_4h_R1 1 SGDETPGSEVPGDK 14 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 0 SGDET(0.999)PGS(0.001)EVPGDK 202.32 1.71E-08 78676000 5639.8 5064.2 5177.6 5093 6477.8 5967.4 6331.1 9966.9 4357.3 4707.7 TRUE FALSE FALSE 5193.403879 5501.926882 5369.486411 5071.926515 6400.556466 4729.693974 6508.733627 13005.76193 3879.315091 4871.292225 1.066124478 1.129459418 1.102271464 1.041187078 1.313933998 0.970932097 1.336141074 2.669879229 0.796362631 1 12.25008882 -4.260533242 2.91401586 1.061956432 2.949770819 0.937610921 0.124562746 0.050317481 0.601858545 0.012935754 0.222479811 5.49E-05 4.260533242 1.887814387 up GSEGDCS(ph)PEDKNSVTAK ddPTM_HeLa_Curcumin_4h_R1 1 GSEGDCSPEDKNSVTAK 17 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 0 GSEGDCS(0.952)PEDKNS(0.048)VTAK 153.48 0.0018127 24340000 5208 3648 4498.7 4844.1 4579.8 5387.6 3394.4 3202 4980.4 4608.2 TRUE FALSE FALSE 4795.781305 3963.316865 4665.425779 4824.056398 4525.188876 4270.151029 3489.637728 4178.27506 4434.06258 4768.334607 1.005756034 0.831174234 0.978418287 1.011685797 0.949008249 0.895522521 0.731835749 0.876254584 0.929897531 1 12.21926976 -5.11830108 2.528560162 0.98620647 0.804456174 0.431077737 0.064140399 0.149298672 1.837830049 0.008864526 0.02827025 7.62E-06 5.11830108 -0.181750296 GSEGSQS(ph)PGSSVDDAEDDPSR ddPTM_HeLa_Curcumin_4h_R1 2 GSEGSQSPGSSVDDAEDDPSR 21 0 Q8IX07 Q8IX07 ZFPM1 Zinc finger protein ZFPM1 1 0 GS(0.024)EGS(0.033)QS(0.943)PGSSVDDAEDDPSR;GS(0.009)EGS(0.093)QS(0.768)PGS(0.109)S(0.02)VDDAEDDPSR ; 105.96 0.0009322 0 975.22 868.64 772.52 709.62 969.75 887.92 828.36 587.62 855.8 724.21 TRUE FALSE FALSE 898.030308 943.721371 801.1502708 706.6837805 958.1863646 703.7553831 851.6015522 766.7826329 761.9208811 749.3762436 1.198370399 1.259342525 1.069089496 0.943029335 1.278645237 0.939121555 1.136413863 1.023227837 1.016740106 1 9.549546432 -6.570493491 24.99985282 1.111360109 1.066379263 0.047619774 0.115783016 404.4871658 212372.2899 0.01926269 0.027241562 2.69E-07 6.570493491 -0.044980846 S(ph)STVAPAQPDGAESEWTDVETR ddPTM_HeLa_Curcumin_4h_R1 2 SSTVAPAQPDGAESEWTDVETR 22 0 Q02241-2;A0A2U3TZL8;H7BYN4;Q02241-3;Q02241 Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 0 S(0.82)S(0.17)T(0.01)VAPAQPDGAESEWTDVETR;S(0.456)S(0.088)T(0.456)VAPAQPDGAESEWTDVETR ; 139.69 9.29E-06 12241600 6310.1 4272 5137.8 5745.2 5349.2 6628.3 3604.2 1796.44 6914.2 5010.5 TRUE FALSE FALSE 5810.648927 4641.252644 5328.211388 5721.427885 5285.414284 5253.515864 3705.324152 2344.166286 6155.729558 5184.614502 1.1207485 0.89519725 1.027696733 1.103539691 1.019442098 1.013289582 0.714676887 0.452138975 1.18730709 1 12.34002101 -4.522755096 1.934240975 1.045796301 0.407602297 0.870303046 0.074899239 0.107125185 0.605652348 0.009685698 0.100681702 3.00E-05 4.522755096 -0.638194005 down GSES(ph)PEMGPEVTPAPR ddPTM_HeLa_Curcumin_4h_R1 1 GSESPEMGPEVTPAPR 16 0 A0A0A0MSQ2;F8W689;P48382-2;P48382;H0Y4B4 A0A0A0MSQ2 RFX5 DNA-binding protein RFX5 1 0 GS(0.009)ES(0.99)PEMGPEVTPAPR 81.632 0.013414 12416000 2576 2452.9 2211.1 2653 2705.3 2615.2 2536.8 2475.4 2624.3 2183.3 TRUE FALSE FALSE 2372.106882 2664.917746 2293.045311 2642.022589 2673.041064 2072.778041 2607.975781 3230.138065 2336.420856 2259.169512 1.049990657 1.179600615 1.014994802 1.16946629 1.183196325 0.917495579 1.154395793 1.429790039 1.034194576 1 11.14157681 -4.329827075 3.323278634 1.050360188 1.455202854 0.613183348 0.084684419 0.128396888 2.302370232 0.011906515 0.118194511 4.68E-05 4.329827075 0.404842666 NCPS(ph)PVLIDCPHPNCNKK ddPTM_HeLa_Curcumin_4h_R1 1 NCPSPVLIDCPHPNCNKK 18 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 0 NCPS(1)PVLIDCPHPNCNKK 63.936 0.010162 26308000 1988.5 1717.9 2277.7 2181.4 1863 1941.7 1059.5 265.44 2064 2103.7 TRUE FALSE FALSE 1831.108127 1866.387621 2362.113566 2172.373945 1840.784942 1538.969533 1089.226719 346.3714341 1837.584364 2176.803418 0.841191313 0.857398333 1.085129482 0.997965148 0.845636738 0.706985996 0.500379 0.159119299 0.844166427 1 11.08799541 -4.522747425 1.154044893 0.934859437 7.25E-13 0.910242229 0.077897314 0.240501294 0.352938293 0.013306503 0.240662595 3.00E-05 4.522747425 -0.934859437 down GSET(ph)PGATPGSK ddPTM_HeLa_Curcumin_4h_R1 4 GSETPGATPGSK 12 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 GS(0.007)ET(0.993)PGATPGSK;GSET(1)PGATPGSK;GS(0.002)ET(0.998)PGATPGSK;GS(0.138)ET(0.862)PGATPGSK ;;; 221.09 4.12E-13 1109755000 42025.6 35153.7 38831.5 40889.7 41865.1 49031 35225.2 18236.2 40864.8 35354.4 TRUE FALSE FALSE 38699.22941 38192.22919 40270.62955 40720.50926 41365.88603 38861.41791 36213.52431 23796.33343 36382.03368 36582.96277 1.057848421 1.043989505 1.100802847 1.113100366 1.130741823 1.062281865 0.989901352 0.65047584 0.994507577 1 15.1588843 -4.26044939 3.117456955 1.049437265 0.589032341 0.887263646 0.043706231 0.100168513 1.467601997 0.007142081 0.112795211 5.49E-05 4.26044939 -0.460404924 GSETDS(ph)AQDQPVK ddPTM_HeLa_Curcumin_4h_R1 2 GSETDSAQDQPVK 13 0 P30419;B7Z8J4;K7EN42 P30419 NMT1 Glycylpeptide N-tetradecanoyltransferase 1 1 0 GS(0.053)ET(0.147)DS(0.8)AQDQPVK;GSET(0.041)DS(0.959)AQDQPVK ; 166.79 0.00018325 45102000 7431 6843 6790.7 6872.5 7546.5 8532.4 6588.3 4222.36 7419 6421.5 TRUE FALSE FALSE 6842.828509 7434.478428 7042.369316 6844.063416 7456.512916 6762.68406 6773.149966 5509.738127 6605.154261 6644.646647 1.029825794 1.118867387 1.059856105 1.030011644 1.122183513 1.017764287 1.019339376 0.829199568 0.994056511 1 12.69797677 -4.253407845 3.892698412 1.033849515 0.807909543 0.68482806 0.043282687 0.12842183 3.826027146 0.006415589 0.082972255 5.58E-05 4.253407845 -0.225939972 GSETPGATPGSK ddPTM_HeLa_Curcumin_4h_R1 2 GSETPGATPGSK 12 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 0 0 ; ; 157.38 1.85E-05 1919150 2151.56 1704.2 2084.32 2008.24 1993.76 2248.9 1604.88 1769.95 1849.58 1989.41 FALSE FALSE TRUE 1981.261756 1851.503454 2161.566733 1999.930435 1969.985714 1782.45279 1649.908613 2309.599607 1646.685701 2058.541849 0.962458818 0.899424733 1.050047505 0.971527703 0.956981134 0.86588125 0.801493841 1.121959025 0.799928212 1 11.00740706 -5.491654375 7.342523956 0.979361911 0.915884098 0 0.101198277 0.377786091 71.56539956 0.011069371 0.024317007 3.22E-06 5.491654375 -0.063477813 GSFS(ph)DTGLGDGK ddPTM_HeLa_Curcumin_4h_R1 3 GSFSDTGLGDGK 12 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 GS(0.165)FS(0.666)DT(0.169)GLGDGK;GS(0.026)FS(0.487)DT(0.487)GLGDGK;GSFS(0.953)DT(0.047)GLGDGK ;; 139.19 0.0012874 392135000 9243.8 8466.5 8072.7 8658.7 8337.7 10360.7 7167.3 8499.2 9325.8 9146.9 TRUE FALSE FALSE 8512.143476 9198.306534 8371.881363 8622.872594 8238.278373 8211.774031 7368.395148 11090.56695 8302.783072 9464.754094 0.899351784 0.971848443 0.884532369 0.911050885 0.870416525 0.867616205 0.778508884 1.171775499 0.877231779 1 13.20834931 -9.407685373 0.644615633 1.015563588 0.90910112 0 0.104175966 2.052779154 1.164714852 0.129637058 0.019273381 3.91E-10 9.407685373 -0.106462468 GSFSDT(ph)GLGDGK ddPTM_HeLa_Curcumin_4h_R1 1 GSFSDTGLGDGK 12 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 GSFS(0.327)DT(0.673)GLGDGK 120.84 0.010088 171660000 2026.6 1851.2 2133.4 2033.8 1955.3 2381.9 2035 1908.9 2236 2138.2 TRUE FALSE FALSE 1866.192472 2011.209479 2212.465681 2025.384674 1931.984325 1887.86709 2092.096623 2490.914823 1990.716394 2212.502291 0.84347595 0.909020292 0.999983453 0.915427154 0.87321235 0.853272378 0.945579416 1.125836042 0.899757891 1 11.11146323 -4.275403065 4.214110696 0.919668259 1.139656985 0.608518892 0.050880024 0.139524552 5.541867885 0.009204891 0.089954537 5.30E-05 4.275403065 0.219988725 GSGDISSDSIDHS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 2 GSGDISSDSIDHSPAK 16 0 Q5JSS2;H0Y306;Q9H5I1-3;Q9H5I1-2;Q9H5I1 Q5JSS2 SUV39H2 Histone-lysine N-methyltransferase SUV39H2 1 0 GSGDISSDSIDHS(1)PAK;GSGDISSDSIDHS(1)PAK ; 100.27 0.0013417 64620000 5021.7 4023.5 4609 4168.2 5915.4 8543.5 5033.2 3987.1 6373.6 4286 TRUE FALSE FALSE 4624.227146 4371.273412 4779.813594 4150.953093 5844.862718 6771.481795 5174.418046 5202.748436 5674.432026 4434.938181 1.042681309 0.985644722 1.077763297 0.935966393 1.317913008 1.526849196 1.16673961 1.173127612 1.279483906 1 12.11469828 -5.753174938 24.99971073 1.01728739 1.303391287 0.443884163 0.129131361 83.46633656 252481.3439 0.014202775 0.028027828 1.77E-06 5.753174938 0.286103897 GSGEKPVSAPGDDT(ph)ES(ph)LHSQGEEEFDMPQPPHGHVLHR ddPTM_HeLa_Curcumin_4h_R1 1 GSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHR 38 1 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 GS(0.001)GEKPVS(0.005)APGDDT(0.665)ES(0.665)LHS(0.665)QGEEEFDMPQPPHGHVLHR 63.848 3.26E-05 12919000 962.92 999.08 956.28 892.18 965.05 1329.9 800.07 701.64 1155.2 1020.6 TRUE FALSE FALSE 886.7038659 1085.436023 991.720578 888.4883956 953.542409 1054.063749 822.5178109 915.566806 1028.47745 1056.065774 0.839629394 1.027811004 0.939070844 0.841319184 0.902919527 0.998104261 0.778850931 0.866960021 0.97387632 1 10.04448398 -9.557025834 1.282350067 1.000905831 0.894473289 0.189688048 0.071431474 0.563149129 1.636124088 0.052992435 0.012056342 2.77E-10 9.557025834 -0.106432542 GSGFTVTGGTEELPEEEGGGGS(ph)GGRR ddPTM_HeLa_Curcumin_4h_R1 1 GSGFTVTGGTEELPEEEGGGGSGGRR 26 1 Q7Z3Z5;Q93074-3;Q93074;Q93074-2 Q7Z3Z5 TNRC11;MED12 Mediator of RNA polymerase II transcription subunit 12 1 0 GSGFTVTGGTEELPEEEGGGGS(1)GGRR 66.474 0.0019586 0 675.83 530.38 708.07 855.32 967.56 881.67 877.58 1011.3 789.88 1060.8 TRUE FALSE FALSE 622.3373424 576.2236839 734.3116971 851.7809125 956.0224789 698.8017035 902.2025329 1319.640715 703.2321402 1097.662721 0.566965909 0.524955137 0.668977531 0.775995118 0.870961964 0.63662698 0.821930558 1.20222787 0.640663226 1 10.10021911 -4.278062432 3.89405456 0.757764584 1.237845916 0.500448839 0.141115592 0.205912342 6.214314467 0.025974219 0.272536594 5.27E-05 4.278062432 0.480081332 GSGGFGS(ph)TGKN ddPTM_HeLa_Curcumin_4h_R1 1 GSGGFGSTGKN 11 1 P33316;A0A0C4DGL3;H0YNW5;P33316-2 P33316;H0YNW5;P33316-2 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 1 0 GSGGFGS(0.835)T(0.165)GKN 124.12 0.0057688 18673000 4840.7 5947.4 5116.1 4693.6 6355.7 7822.2 6038 3196.2 5000.1 5267.1 TRUE FALSE FALSE 4457.553487 6461.466755 5305.707167 4674.179127 6279.912429 6199.787546 6207.41003 4170.706667 4451.60154 5450.131333 0.817880013 1.185561661 0.973500792 0.857626879 1.152249743 1.137548284 1.138946871 0.765248837 0.816787939 1 12.41207528 -7.27869326 24.92770012 0.9139989 1.034304695 0.188243743 0.138487245 1176.650565 1699972.302 0.023944095 0.027418053 5.26E-08 7.27869326 0.120305795 GSGGFGSTGK(ac)N ddPTM_HeLa_Curcumin_4h_R1 2 GSGGFGSTGKN 11 1 P33316;A0A0C4DGL3;H0YNW5;P33316-2 P33316;H0YNW5;P33316-2 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 0 1 ; GSGGFGSTGK(1)N;GSGGFGSTGK(1)N 115.91 0.00089587 18995400 14993.7 14124.3 14428.8 13347.5 13707.5 17907.8 13153.2 15010 14603.6 13582.7 FALSE TRUE FALSE 13806.93282 15345.14156 14963.54402 13292.27158 13544.04702 14193.52042 13522.24339 19586.4799 13001.62162 14054.69781 0.982371375 1.09181583 1.064664941 0.945752926 0.963666896 1.00987731 0.962115555 1.393589543 0.92507301 1 13.77876481 -4.258290067 24.98720183 0.997869048 1.39358969 0.856101597 0.049132541 71.97269431 571015.6978 0.006081756 0.058033911 5.52E-05 4.258290067 0.395720641 GSGGGGGGGGQGSTNYGK ddPTM_HeLa_Curcumin_4h_R1 1 GSGGGGGGGGQGSTNYGK 18 0 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 0 0 212.39 2.52E-19 490950 0 0 0 0 0 139.07 0 0 0 147.74 FALSE FALSE TRUE 0 0 0 0 0 110.2253144 0 0 0 152.873954 0 0 0 0 0 0.72102089 0 0 0 1 7.256198817 -9.214336428 0.852006603 1.026448455 0.092374578 0 0.372610777 0.28298613 0.353702806 0.172034009 0.043150338 6.10E-10 9.214336428 -0.934073877 GSGGGGGGGGQGSTNYGK(ac)SQR ddPTM_HeLa_Curcumin_4h_R1 2 GSGGGGGGGGQGSTNYGKSQR 21 1 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 0 1 ; GSGGGGGGGGQGSTNYGK(1)SQR;GSGGGGGGGGQGSTNYGK(1)SQR 375.8 2.30E-292 6479100 487.25 536.97 292.71 271.7 382.7 473.15 387.47 459.66 486.71 247.38 FALSE TRUE FALSE 448.6836484 583.3832941 303.5580901 270.5757774 378.1365524 375.0133565 398.3413654 599.808218 433.3191307 255.9764366 1.75283184 2.279050767 1.185882944 1.057033925 1.477231879 1.465030772 1.556164195 2.343216532 1.692808668 1 7.999867202 -9.299738035 1.056854764 1.004375747 1.617879529 0 0.443733261 0.586122382 1.185616161 0.261956656 0.072235487 5.01E-10 9.299738035 0.613503782 GSGGGGGGGGQGSTNYGKS(ph)QR ddPTM_HeLa_Curcumin_4h_R1 1 GSGGGGGGGGQGSTNYGKSQR 21 1 Q99729-3;Q99729-4 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 1 0 GSGGGGGGGGQGSTNYGKS(1)QR 114.71 6.23E-06 1628400 353.33 313.89 313.98 340.67 210.29 519.48 394.72 605.97 525.09 402.08 TRUE FALSE FALSE 325.3635577 341.0212529 325.616375 339.2603978 207.7824291 411.7339923 405.7947809 790.7274635 467.4889407 416.0522501 0.782025713 0.819659677 0.782633371 0.815427384 0.499414266 0.989620876 0.975345719 1.900548461 1.123630363 1 8.700620911 -4.189989776 2.444649877 0.852290955 2.265339025 0.794967378 0.158753882 0.227411492 1.393114225 0.021041949 0.720580123 6.46E-05 4.189989776 1.413048071 GSGGGGGPQVPHQS(ph)PPKR ddPTM_HeLa_Curcumin_4h_R1 2 GSGGGGGPQVPHQSPPKR 18 1 Q9NYF3;D6RHW3 Q9NYF3 FAM53C Protein FAM53C 1 0 GSGGGGGPQVPHQS(1)PPKR;GSGGGGGPQVPHQS(1)PPKR ; 76.807 0.0039214 7340400 5807 4601.4 5624.3 4825.8 5088.2 6889.7 5344.4 4055 5815.1 4787.5 TRUE FALSE FALSE 5347.369822 4999.124513 5832.741506 4805.832118 5027.526538 5460.698557 5494.34948 5291.350833 5177.198079 4953.865269 1.079433843 1.009136148 1.17741222 0.970117647 1.014869454 1.102310673 1.109103535 1.068125705 1.045082536 1 12.27433892 -9.389449278 0.78922851 0.993421707 1.067243116 0.062655844 0.057192577 1.182016993 1.121011493 0.057950951 0.01053472 4.08E-10 9.389449278 0.073821408 GSGIFDEST(ph)PVQTR ddPTM_HeLa_Curcumin_4h_R1 1 GSGIFDESTPVQTR 14 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2;H3BMV3;H3BMT0;H3BTV5 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 0 GSGIFDES(0.029)T(0.971)PVQTR 177.93 0.00047073 25795000 4295.1 3537.2 3810.3 4249.3 4024.2 8433.4 7762.5 2717.8 4386.4 3150.9 TRUE FALSE FALSE 3955.138303 3842.939807 3951.51307 4231.717523 3976.214043 6684.217776 7980.294858 3546.444709 3905.222894 3260.39354 1.213086167 1.178673605 1.211974267 1.297916178 1.219550338 2.050126064 2.447647733 1.087735166 1.19777654 1 11.6708304 -5.312437633 5.757967841 1.137292207 1.920141248 0.467623315 0.324668325 0.108433698 8.491091912 0.04320974 0.099121536 4.87E-06 5.312437633 0.782849041 GSGS(ph)PTHSLSQK ddPTM_HeLa_Curcumin_4h_R1 2 GSGSPTHSLSQK 12 0 I3L2R2;I3L419;I3L156;Q9BSJ6-2;Q9BSJ6 I3L2R2 FAM64A Protein FAM64A 1 0 GSGS(0.992)PT(0.001)HS(0.007)LSQK;GSGS(0.857)PT(0.082)HS(0.05)LS(0.011)QK ; 188.96 6.46E-06 100991000 6106.3 4664.9 4440 4740.6 5694.4 9852 7356 3462.67 7674.3 5147.6 TRUE FALSE FALSE 5622.979912 5068.11317 4604.550306 4720.984653 5626.497999 7808.584145 7562.389562 4518.422143 6832.44849 5326.478717 1.055665518 0.951494118 0.864464227 0.886323762 1.056326008 1.465993682 1.419772793 0.848294414 1.282732712 1 12.37896638 -5.498439449 22.19903218 0.997348669 1.262023174 0.240946944 0.188308199 152.281842 138321.4731 0.022807068 0.050663046 3.17E-06 5.498439449 0.264674505 PLPPAAIES(ph)PAVAAPAYSR ddPTM_HeLa_Curcumin_4h_R1 1 PLPPAAIESPAVAAPAYSR 19 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 0 PLPPAAIES(0.99)PAVAAPAYS(0.01)R 102.5 0.0017822 0 930.47 891.66 975.12 1107.5 1069 1452.3 1154.8 4837.1 1176.8 981.28 TRUE FALSE FALSE 856.8223177 968.7311172 1011.258805 1102.917458 1056.252873 1151.076609 1187.20058 6311.909523 1047.707984 1015.379407 0.84384449 0.954058267 0.995941811 1.08621216 1.040254378 1.13364187 1.16921869 6.216306417 1.031838914 1 9.987803191 -4.260493779 5.22500035 0.9677471 6.445313113 0.997179462 0.082787298 0.007276404 0.675702526 0.015207277 0.142598893 5.49E-05 4.260493779 5.477566013 up SETIQDTDTQSLVGSPS(ph)TR ddPTM_HeLa_Curcumin_4h_R1 1 SETIQDTDTQSLVGSPSTR 19 0 E9PMR6;Q9NZN5-2;Q9NZN5 E9PMR6 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 0 SETIQDTDTQSLVGS(0.179)PS(0.643)T(0.179)R 186.89 6.17E-08 7338300 1403.6 1009.9 1039.8 735.7 1264 1308.6 1137 1622.1 938.99 875.76 TRUE FALSE FALSE 1292.503579 1097.191256 1078.335903 732.6558683 1248.927626 1037.181609 1168.90116 2116.670823 835.9851462 906.1925948 1.426301193 1.210770494 1.189963269 0.808499068 1.378214336 1.144548758 1.289903677 2.335784727 0.922524804 1 9.823673891 -4.260420102 3.949613152 1.187180917 2.443451527 0.785213653 0.185652475 0.089754438 2.843552142 0.027125129 0.323282841 5.49E-05 4.260420102 1.25627061 up GSGTAEVELK ddPTM_HeLa_Curcumin_4h_R1 2 GSGTAEVELK 10 0 P14618;P14618-3;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 167.12 2.57E-12 27019000 6149.5 4852.1 5523.3 5340.4 5836.6 6465.9 5268.7 5161.3 6163.6 5216.7 FALSE FALSE TRUE 5662.760586 5271.493903 5727.998357 5318.30284 5767.002357 5124.799454 5416.525542 6734.95661 5487.468501 5397.979937 1.049051803 0.976567895 1.061137393 0.98523946 1.068363059 0.94939209 1.003435657 1.247680927 1.016578158 1 12.3982039 -4.25928951 24.90539447 1.017600649 1.24768101 0.787999688 0.036546222 60.10659664 696258.3185 0.00482819 0.042487283 5.50E-05 4.25928951 0.230080362 GSGTAEVELK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 GSGTAEVELKK 11 1 P14618;P14618-3;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 1 ; GSGTAEVELK(1)K;GSGTAEVELK(1)K 219.5 4.20E-31 88100000 4253.9 5986.6 3758.2 3619.6 8010.5 10310.4 7952.7 7217 10146.5 4744 FALSE TRUE FALSE 3917.199326 6504.055028 3897.482198 3604.623054 7914.980019 8171.906818 8175.831358 9417.430077 9033.454335 4908.853647 0.797986579 1.324964135 0.793969932 0.734310557 1.612388673 1.664728143 1.665527625 1.918458107 1.840237046 1 12.26117044 -5.690664935 5.785740475 0.917908614 1.720803121 0.415041392 0.337291788 0.059762631 3.569807319 0.025248404 0.050743879 2.04E-06 5.690664935 0.802894507 GSGTAEVELKK ddPTM_HeLa_Curcumin_4h_R1 2 GSGTAEVELKK 11 1 P14618;P14618-3;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 92.611 0.0051658 159629000 14188.8 11129.3 12011.7 12083.9 12322.4 14960.7 12901.2 12179.3 14225.8 12761.5 FALSE FALSE TRUE 13065.74151 12091.2671 12456.86417 12033.90002 12175.46343 11857.68218 13263.17295 15892.7125 12665.26533 13204.96118 0.989457018 0.915660935 0.943347277 0.911316577 0.922037049 0.897971756 1.004408326 1.203541025 0.959129312 1 13.68879244 -4.281050818 3.907135508 0.968708593 1.221551865 0.781962299 0.039483174 0.10033601 3.051173457 0.006807011 0.069659509 5.24E-05 4.281050818 0.252843272 GSGTAS(ph)DDEFENLR ddPTM_HeLa_Curcumin_4h_R1 4 GSGTASDDEFENLR 14 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 GSGT(0.002)AS(0.998)DDEFENLR;GSGT(0.002)AS(0.998)DDEFENLR;GSGT(0.001)AS(0.999)DDEFENLR;GSGT(0.002)AS(0.998)DDEFENLR ;;; 172.09 0.00019802 760528000 7962.1 6522 7389.4 7596.1 7579.5 7998.3 5717.98 4996.4 8016.7 7413.2 TRUE FALSE FALSE 7331.891383 7085.732619 7663.257664 7564.669351 7489.119413 6339.362421 5878.41113 6519.779359 7137.288067 7670.808148 0.955817333 0.923727003 0.999015686 0.986163284 0.976314264 0.826426929 0.766335309 0.849946868 0.930447996 1 12.90516286 -5.233228839 4.679608156 0.976573055 0.806389367 0.828297263 0.031789072 0.050069919 2.829184247 0.004233562 0.01084016 5.84E-06 5.233228839 -0.170183688 S(ph)FSSPENFQR ddPTM_HeLa_Curcumin_4h_R1 1 SFSSPENFQR 10 0 G3V1T9;J3KPD3;Q9Y580;I3L521;F5GXV8;F5GY08 G3V1T9 RBM7 RNA-binding protein 7 1 0 S(0.406)FS(0.406)S(0.188)PENFQR 156.01 0.00063761 73862000 969.22 670.4 1092.1 1168.7 1038.3 1309 1701.8 12882 0 845.85 TRUE FALSE FALSE 892.5052143 728.3463888 1132.574187 1163.864229 1025.918951 1037.498645 1749.547928 16809.6625 0 875.2432245 1.019722506 0.832164555 1.294010802 1.329760913 1.172152976 1.185383235 1.998927702 19.20570423 0 1 9.773540178 -4.260417663 4.80525823 1.074435242 20.22396922 0.995426032 0.368877594 0.004230182 0.278543856 0.027145075 0.27004137 5.49E-05 4.260417663 19.14953398 up GSIS(ph)TPNSPVK ddPTM_HeLa_Curcumin_4h_R1 1 GSISTPNSPVK 11 0 Q96AY4;A0A087WW06 Q96AY4 TTC28 Tetratricopeptide repeat protein 28 1 0 GS(0.018)IS(0.764)T(0.091)PNS(0.128)PVK 126.5 0.003353 8489000 4696.2 2947.4 3590.7 3291.3 3830.5 4172.6 2788.3 2409.1 3756.4 3697.3 TRUE FALSE FALSE 4324.490815 3202.160123 3723.774501 3277.681473 3784.823789 3307.155725 2866.532194 3143.6235 3344.332318 3825.7809 1.130355064 0.836995167 0.973337104 0.856735281 0.989294444 0.864439395 0.749267213 0.821694598 0.874156781 1 11.90153854 -6.037745873 0.591554134 1.056724896 0.789542696 0.14424342 0.097950302 0.557021019 0.352855044 0.020738185 0.070385645 9.17E-07 6.037745873 -0.2671822 MSSLS(ph)QS(ph)MRK ddPTM_HeLa_Curcumin_4h_R1 1 MSSLSQSMRK 10 1 F5H2B9;H0YNH8;Q9BZF9-2;Q9BZF9 F5H2B9 UACA Uveal autoantigen with coiled-coil domains and ankyrin repeats 2 0 MS(0.006)S(0.026)LS(0.968)QS(1)MRK 68.016 0.019109 17735000 9989.3 7537.4 8255.9 8097.4 7791.8 9897 4183.7 1180 9664.6 7382.2 TRUE FALSE FALSE 9198.636364 8188.89927 8561.870917 8063.895104 7698.887874 7844.250638 4301.083362 1539.776568 8604.41756 7638.730901 1.20421003 1.072023531 1.12084992 1.055659011 1.007875258 1.026904958 0.563062558 0.20157492 1.126419777 1 12.89911725 -4.52175114 1.664257088 1.092724265 0.088878773 0.960117615 0.058943321 0.106126789 0.405945761 0.011651497 0.144649075 3.01E-05 4.52175114 -1.003845492 down GSISTPNS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 1 GSISTPNSPVK 11 0 Q96AY4;A0A087WW06 Q96AY4 TTC28 Tetratricopeptide repeat protein 28 1 0 GS(0.005)IS(0.145)T(0.412)PNS(0.438)PVK 120.84 0.0040901 7211100 4291.2 2919.1 3579.8 3285.5 3273.5 3362.4 2543.8 2457.3 3633 3152.5 TRUE FALSE FALSE 3951.546992 3171.413997 3712.470537 3271.905472 3234.46565 2665.000338 2615.172182 3206.519458 3234.468989 3262.04914 1.211369548 0.972215273 1.13807928 1.003021515 0.991544122 0.816971242 0.801696133 0.982977055 0.991545145 1 11.6715628 -5.674554486 1.754389534 1.092822442 0.862597061 0.44528191 0.087163278 0.217687232 1.351444801 0.014902504 0.036395281 2.12E-06 5.674554486 -0.23022538 GSK(ac)K(ac)AVTK ddPTM_HeLa_Curcumin_4h_R1 2 GSKKAVTK 8 2 P58876;P62807;P57053;O60814;Q16778;P06899;Q5QNW6;Q5QNW6-2;Q8N257;Q93079;U3KQK0;Q99877;Q99880 P58876;P62807;Q16778;Q5QNW6;Q8N257;Q93079;U3KQK0;Q99880 HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST2H2BF;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BL Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 2-F;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-L 0 2 ; GSK(1)K(1)AVTK;GSK(1)K(1)AVTK 112.36 0.010961 36788000 12490.9 9194.6 11299.2 11074.7 12064.8 12935.7 11379.8 4975.3 11854.4 8864.3 FALSE TRUE FALSE 11502.23208 9989.340254 11717.95829 11028.87583 11920.93514 10252.69 11699.08656 6492.246067 10554.00198 9172.333765 1.254013687 1.089072913 1.277532915 1.202406727 1.299662163 1.117784227 1.275475453 0.707807438 1.150634315 1 13.16307314 -4.251731973 24.51271955 1.155741808 0.70780712 0.682258393 0.095856354 586.6584398 1481364.346 0.016487586 0.28404525 5.60E-05 4.251731973 -0.447934688 GSK(ac)K(ac)AVTK(ac)AQK ddPTM_HeLa_Curcumin_4h_R1 2 GSKKAVTKAQK 11 3 P58876;P62807;P57053;O60814;Q16778;P06899;Q8N257;Q93079;U3KQK0;Q99877;Q99880 P58876;P62807;Q16778;Q8N257;Q93079;U3KQK0;Q99880 HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BL Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-L 0 3 ; GSK(1)K(1)AVTK(1)AQK;GSK(1)K(1)AVTK(1)AQK 167.71 3.19E-09 85444000 11215 8093.3 11502.8 10024.7 12243.9 12972.8 12587.1 7613.6 9501.9 8220.7 FALSE TRUE FALSE 10327.32092 8792.848789 11929.10389 9983.220448 12097.89949 10282.09505 12940.26015 9934.951591 8459.565343 8506.368713 1.214069277 1.033678305 1.402373244 1.173617178 1.422216682 1.20875257 1.521243739 1.167942741 0.994497844 1 13.05432768 -8.630764985 0.211269569 0.855055573 1.393235889 0.45551207 0.128552492 3.206116946 0.319679633 0.545174851 0.203350115 2.34E-09 8.630764985 0.538180316 GSK(ac)K(ac)AVTK(ac)VQK ddPTM_HeLa_Curcumin_4h_R1 2 GSKKAVTKVQK 11 3 Q5QNW6;Q5QNW6-2 Q5QNW6 HIST2H2BF Histone H2B type 2-F 0 3 ; GSK(1)K(1)AVTK(1)VQK;GSK(1)K(1)AVTK(1)VQK 137.59 0.00016195 14524200 5827.4 4727 5187.6 5692.3 6439.1 7395.5 6557 3500 5564.2 4639.2 FALSE TRUE FALSE 5366.155141 5135.580817 5379.857019 5668.746771 6362.317938 5861.589936 6740.971773 4567.133888 4953.821181 4800.411855 1.117853072 1.069820876 1.120707386 1.180887587 1.325369183 1.221059799 1.40424863 0.951404593 1.031957534 1 12.22894247 -6.372661856 1.78335639 1.057188501 1.238378574 0.314983589 0.112575504 0.286968765 1.790178089 0.017500524 0.029763308 4.24E-07 6.372661856 0.181190073 GSLAEAVGS(ph)PPPAATPTPTPPTR ddPTM_HeLa_Curcumin_4h_R1 1 GSLAEAVGSPPPAATPTPTPPTR 23 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 0 GSLAEAVGS(1)PPPAATPTPTPPTR 119.66 4.87E-06 31474000 3659.7 2962.3 3375 3009.6 3275.3 4008.5 2323.7 3484.9 4153.4 3091.1 TRUE FALSE FALSE 3370.030883 3218.348012 3500.080469 2997.147073 3236.244187 3177.091915 2388.896768 4547.429967 3697.782411 3198.515495 1.053623435 1.006200538 1.094282793 0.937043162 1.011795688 0.993302024 0.746876722 1.421731417 1.156093324 1 11.64318676 -6.264822594 24.18912056 1.028928911 1.004678978 0 0.163570972 1363.391948 9747838.736 0.021715584 0.034052529 5.43E-07 6.264822594 -0.024249933 GSLAEAVGS(ph)PPPAATPTPTPPTRK ddPTM_HeLa_Curcumin_4h_R1 2 GSLAEAVGSPPPAATPTPTPPTRK 24 1 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 0 GS(0.002)LAEAVGS(0.806)PPPAAT(0.124)PT(0.06)PT(0.004)PPT(0.004)RK;GSLAEAVGS(1)PPPAATPTPTPPTRK ; 144 8.47E-07 18126000 5269.4 3524 4581.7 4276.3 4192 5647.6 3281.4 3494.6 5266.6 4149.4 TRUE FALSE FALSE 4852.32143 3828.598857 4751.501832 4258.605804 4142.013138 4476.224098 3373.467253 4560.087453 4688.867156 4293.591341 1.130131176 0.891700805 1.106649761 0.991851684 0.964696639 1.042536129 0.785698262 1.062068346 1.092061816 1 12.06796917 -5.783482366 0.928685426 1.053333533 0.938563153 0.130255853 0.093705699 0.767836749 1.254565333 0.015962402 0.051721272 1.65E-06 5.783482366 -0.11477038 GSLAEAVGSPPPAAT(ph)PTPTPPTR ddPTM_HeLa_Curcumin_4h_R1 1 GSLAEAVGSPPPAATPTPTPPTR 23 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 0 GSLAEAVGSPPPAAT(0.888)PT(0.094)PT(0.016)PPT(0.002)R 135.36 3.69E-05 7359500 2942.2 2340.2 3065 2798.8 2312.1 2139.9 1152.7 1222.2 2842.7 2086.9 TRUE FALSE FALSE 2709.321765 2542.47646 3178.591596 2787.219307 2284.529718 1696.060618 1185.04166 1594.843154 2530.862922 2159.41962 1.254652751 1.177388793 1.471965693 1.29072612 1.057936909 0.785424289 0.548777852 0.738551757 1.17201071 1 11.0764279 -5.232023791 2.706855085 1.167657724 0.647491968 0.771404356 0.129161249 0.126972925 1.831039567 0.023181837 0.065847209 5.86E-06 5.232023791 -0.520165756 GSLAS(ph)LDSLR ddPTM_HeLa_Curcumin_4h_R1 1 GSLASLDSLR 10 0 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12;O60716-25;O60716-26;O60716-27;O60716-29;O60716-32;O60716-28;O60716-31;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 0 GS(0.004)LAS(0.996)LDSLR 147.28 0.00099567 120690000 6065.7 4686.7 4986.5 4743.3 5324.4 6512 4110.1 2826.1 6656.4 4244.7 TRUE FALSE FALSE 5585.593445 5091.797464 5171.304077 4723.673481 5260.910007 5161.337795 4225.418344 3687.76488 5926.209573 4392.203009 1.271706575 1.159280993 1.177382754 1.075467931 1.19778389 1.175113669 0.962027105 0.839616218 1.349256754 1 12.10072902 -4.583081277 3.442622214 1.140181574 0.856222194 0.559107228 0.096095142 0.148514519 3.408149984 0.014449271 0.073286114 2.61E-05 4.583081277 -0.28395938 GSLAS(ph)LDSLRK ddPTM_HeLa_Curcumin_4h_R1 1 GSLASLDSLRK 11 1 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12;O60716-25;O60716-26;O60716-27;O60716-29;O60716-32;O60716-28;O60716-31;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 0 GSLAS(0.999)LDS(0.001)LRK 110.64 0.010206 253710000 3942.5 3235.1 3673.8 3205.7 3475.9 4191.2 3158.6 2022.7 4468.2 3430.7 TRUE FALSE FALSE 3630.446965 3514.727629 3809.95426 3192.435663 3434.452163 3321.897875 3247.221815 2639.411919 3978.049639 3549.91657 1.022685152 0.990087389 1.073251775 0.899298786 0.967474051 0.935767872 0.914731868 0.743513789 1.120603699 1 11.7935694 -3.147663484 0.586867062 1.010011587 9.14E-16 0.708324541 0.053421319 3.43428925 0.30618766 0.006837453 3.184342943 0.000711765 3.147663484 -1.010011587 GSLASLDS(ph)LRK ddPTM_HeLa_Curcumin_4h_R1 1 GSLASLDSLRK 11 1 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12;O60716-25;O60716-26;O60716-27;O60716-29;O60716-32;O60716-28;O60716-31;O60716-30;E9PKY0 O60716 CTNND1 Catenin delta-1 1 0 GSLAS(0.001)LDS(0.999)LRK 123.26 0.0059468 24079000 2331.8 1575.3 1950.1 2375.9 2337.5 3383.9 3938.7 1614 2471.7 1940.5 TRUE FALSE FALSE 2147.235569 1711.461913 2022.372421 2366.069155 2309.626839 2682.040996 4049.209322 2106.10117 2200.560694 2007.932231 1.069376514 0.852350436 1.007191573 1.178361062 1.15025139 1.335722867 2.016606567 1.048890564 1.095933747 1 10.97149486 -5.266489988 2.288813184 1.027975391 1.550302685 0.410914855 0.234181784 0.183615247 1.860556302 0.030314703 0.089036474 5.41E-06 5.266489988 0.522327295 GSLDES(ph)SLGFGYPK ddPTM_HeLa_Curcumin_4h_R1 1 GSLDESSLGFGYPK 14 0 Q2KJU6;Q9BUZ4 Q2KJU6 TRAF4 TNF receptor-associated factor 4 1 0 GS(0.044)LDES(0.607)S(0.349)LGFGYPK 161.25 0.00027543 46433000 3669.9 4050.3 4600.5 3420.4 4394.2 6446.6 4695.6 1814.9 3696.6 3516.1 TRUE FALSE FALSE 3379.423543 4400.389884 4770.998577 3406.247291 4341.802035 5109.502492 4827.345898 2368.254655 3291.092228 3638.284213 0.928850894 1.209468427 1.311332017 0.93622353 1.193365273 1.404371454 1.326819351 0.650926238 0.904572605 1 11.82904253 -7.26280535 24.75564077 0.966401809 1.164216559 0.161913379 0.207476246 138.8722366 2516782.619 0.033400757 0.039306163 5.46E-08 7.26280535 0.19781475 EASQTS(ph)SSPAPK ddPTM_HeLa_Curcumin_4h_R1 1 EASQTSSSPAPK 12 0 Q5T8J1;P30281-4;P30281-2;P30281-3;P30281 Q5T8J1 CCND3 G1/S-specific cyclin-D3 1 0 EAS(0.019)QT(0.203)S(0.591)S(0.149)S(0.038)PAPK 113.35 0.0034311 0 3690.8 3482.4 3243.4 3268.6 3276 3835.1 2100.2 1171.6 3293.6 3301.2 TRUE FALSE FALSE 3398.669285 3783.403139 3363.603257 3255.075399 3236.93584 3039.65703 2159.12596 1528.815447 2932.30032 3415.916454 0.99495094 1.1075807 0.984685458 0.95291423 0.947603925 0.889851104 0.632078093 0.447556451 0.858422728 1 11.73805697 -4.518173698 1.150695584 1.003439549 0.301294966 0.897072572 0.059957301 0.141934147 0.205714294 0.005811772 0.106659825 3.03E-05 4.518173698 -0.702144583 down GSLGS(ph)QGAKDEPEEELQK ddPTM_HeLa_Curcumin_4h_R1 2 GSLGSQGAKDEPEEELQK 18 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 GS(0.019)LGS(0.981)QGAKDEPEEELQK;GS(0.019)LGS(0.981)QGAKDEPEEELQK ; 66.76 0.0075071 61554000 4849.4 3639.6 4015.4 4642.5 4457.6 5523.6 5352.5 2994.9 4744.4 4161 TRUE FALSE FALSE 4465.564873 3954.190806 4164.214256 4623.290565 4404.446031 4377.943096 5502.676744 3908.031223 4223.95119 4305.59444 1.037154088 0.918384409 0.967163609 1.073786821 1.022958872 1.016803407 1.278029508 0.907663571 0.981037868 1 12.07199672 -4.951295911 24.99998473 1.011383844 1.106489067 0.124536887 0.092360551 140.6105461 72174.36808 0.011269957 0.033809862 1.12E-05 4.951295911 0.095105223 GSLLPTS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 GSLLPTSPR 9 0 Q9H0E9-4;Q9H0E9-2;H7C128;H7C179;H7C127;Q9H0E9-3 Q9H0E9-4;Q9H0E9-3 BRD8 Bromodomain-containing protein 8 1 0 GSLLPT(0.267)S(0.733)PR 91.265 0.018251 62296000 7968.1 6564.2 7134.4 7336 6868.3 6989.3 5279.5 6005.6 8113.3 7145.5 TRUE FALSE FALSE 7337.416477 7131.580198 7398.80714 7305.645576 6786.400008 5539.640394 5427.628561 7836.679794 7223.291288 7393.805593 0.992373465 0.964534448 1.000676451 0.988076503 0.917849397 0.749227218 0.734077802 1.059898004 0.976938222 1 12.8521014 -5.553981285 3.947126576 0.993126356 0.835192615 0.354320476 0.083483317 0.146137789 4.985809792 0.01121856 0.024101679 2.79E-06 5.553981285 -0.157933741 GSLLTILGSPS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 2 GSLLTILGSPSPER 14 0 Q96A19 Q96A19 CCDC102A Coiled-coil domain-containing protein 102A 1 0 GSLLTILGS(0.074)PS(0.926)PER;GSLLTILGS(0.001)PS(0.999)PER ; 130.61 0.001072 26979000 2729.5 2358.8 2538.9 2419.3 2274.16 2924 2263.7 1698.68 3073.8 2589 TRUE FALSE FALSE 2513.457195 2562.684161 2632.993867 2409.289578 2247.042127 2317.52944 2327.21333 2216.599712 2736.61183 2678.967557 0.938218601 0.956593951 0.982839027 0.899335108 0.838771683 0.865083055 0.86869784 0.827408195 1.021517346 1 11.38746139 -6.062665925 3.249224602 0.969564551 0.852802782 0.853890018 0.025231367 0.076863363 1.6012474 0.004002888 0.007114223 8.66E-07 6.062665925 -0.116761768 GSLPQLVS(ph)PIVSR ddPTM_HeLa_Curcumin_4h_R1 2 GSLPQLVSPIVSR 13 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 0 GSLPQLVS(0.999)PIVS(0.001)R;GSLPQLVS(0.908)PIVS(0.092)R ; 115.58 0.0029142 176362000 2789.6 2849.3 2627.3 3020.7 2819.7 3218.5 2202.8 1590.11 2801.1 2016.34 TRUE FALSE FALSE 2568.800216 3095.580796 2724.670049 3008.201144 2786.076919 2550.94682 2264.604639 2074.927219 2493.826338 2086.407665 1.231207237 1.483689333 1.305914513 1.441808902 1.335346378 1.222650234 1.085408512 0.994497506 1.195272803 1 11.02680536 -8.718919428 0.956348128 1.01958067 1.268119407 0.119427276 0.150320904 0.467833982 0.85578056 0.064394858 0.030438341 1.91E-09 8.718919428 0.248538737 LLHMDS(ph)DDEIPIR ddPTM_HeLa_Curcumin_4h_R1 3 LLHMDSDDEIPIR 13 0 Q1MSJ5-2;Q1MSJ5-1;Q1MSJ5 Q1MSJ5-2 CSPP1 Centrosome and spindle pole-associated protein 1 1 0 LLHMDS(1)DDEIPIR;LLHMDS(1)DDEIPIR;LLHMDS(1)DDEIPIR ;; 136.14 0.00075266 16037900 10167.3 8057.3 8720.3 9408.7 8980.4 10606.8 5688.7 2560.91 9736 7949.6 TRUE FALSE FALSE 9362.547477 8753.737109 9043.481989 9369.769292 8873.314595 8406.830117 5848.309612 3341.71967 8667.985158 8225.848008 1.138186296 1.064174429 1.099398139 1.139064238 1.078711227 1.022001635 0.710967381 0.406246221 1.053749735 1 13.0059487 -4.514998891 1.879212869 1.076447765 0.350024641 0.967431246 0.039940948 0.084969718 0.442175666 0.008187272 0.090015336 3.05E-05 4.514998891 -0.726423124 down GSLVGLVDYPDDEEEDEEEESS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 GSLVGLVDYPDDEEEDEEEESSPR 24 0 Q5MIZ7-5;Q5MIZ7-3;Q5MIZ7-2;Q5MIZ7 Q5MIZ7-5 SMEK2 Serine/threonine-protein phosphatase 4 regulatory subunit 3B 1 0 GSLVGLVDYPDDEEEDEEEES(0.116)S(0.884)PR 146.36 6.03E-07 6137400 6661.2 5818.2 6471.8 5676.5 6944 8316.2 6669.4 4918.8 6382.7 5930.9 TRUE FALSE FALSE 6133.958991 6321.099283 6711.650601 5653.012147 6861.197335 6591.326377 6856.525414 6418.519477 5682.533779 6136.998334 0.999504751 1.029998533 1.093637351 0.921136334 1.11800541 1.074030987 1.117244138 1.045872775 0.925946769 1 12.58331748 -5.822198288 0.723241705 1.001181466 1.094426827 0.309570992 0.056380769 0.684038577 0.641009947 0.009134823 0.034204258 1.51E-06 5.822198288 0.093245361 GSNEEQVNGS(ph)PLER ddPTM_HeLa_Curcumin_4h_R1 2 GSNEEQVNGSPLER 14 0 Q9UHF7;Q9UHF7-3;Q9UHF7-2;E5RFF3;H0YAV4 Q9UHF7 TRPS1 Zinc finger transcription factor Trps1 1 0 GSNEEQVNGS(1)PLER;GSNEEQVNGS(1)PLER ; 177.04 0.00017533 17290200 1962.66 1602.81 1665 1665.84 1853.45 2341.99 2007.66 981.21 1870.58 1722.94 TRUE FALSE FALSE 1807.31339 1741.349754 1726.706365 1658.947195 1831.348819 1856.234874 2063.989536 1280.376412 1665.382054 1782.812037 1.013743094 0.976743324 0.968529676 0.93052277 1.027224846 1.041183723 1.157715729 0.718178016 0.934132157 1 10.79993889 GSNMDFREPTEEER ddPTM_HeLa_Curcumin_4h_R1 3 GSNMDFREPTEEER 14 1 Q15056;Q15056-2 Q15056 EIF4H Eukaryotic translation initiation factor 4H 0 0 ;; ;; 103.11 0.0034657 68207000 11372.3 9421 9432.2 9998.4 9384.6 12229.9 9873 9648.1 12193.4 10503.8 FALSE FALSE TRUE 10472.17046 10235.30926 9781.765629 9957.02927 9272.694774 9693.280881 10150.00981 12589.76128 10855.81453 10868.80627 0.963506957 0.941714206 0.899985278 0.916110659 0.853147489 0.891844113 0.933866108 1.158338916 0.998804676 1 13.40790588 -7.841667549 1.13744885 0.990867202 0.934419861 0.066992314 0.0778047 0.797887934 2.167672923 0.01890584 0.016884916 1.44E-08 7.841667549 -0.056447341 GSNRSS(ph)LMDTADGVPVSSR ddPTM_HeLa_Curcumin_4h_R1 1 GSNRSSLMDTADGVPVSSR 19 1 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 1 0 GS(0.074)NRS(0.084)S(0.808)LMDT(0.034)ADGVPVSSR 152.09 0.00039332 5858700 1062.9 1200.3 982.54 1527.5 1632.1 2043.4 1472.3 578.74 1606 1329.5 TRUE FALSE FALSE 978.7703434 1304.048584 1018.953797 1521.17961 1612.638273 1619.575806 1513.608776 755.1951618 1429.825818 1375.700026 0.71147076 0.947916376 0.740680219 1.105749495 1.172231041 1.177273952 1.100246236 0.548953367 1.039344182 1 10.42595021 -6.250479872 24.84605819 0.859549541 1.042395197 0.090304528 0.195400455 952.6315441 2159689.597 0.029806097 0.04911419 5.62E-07 6.250479872 0.182845656 GSPALLPS(ph)TPTMPLFPHVLDLLAPLDSSR ddPTM_HeLa_Curcumin_4h_R1 1 GSPALLPSTPTMPLFPHVLDLLAPLDSSR 29 0 Q9UGR2 Q9UGR2 ZC3H7B Zinc finger CCCH domain-containing protein 7B 1 0 GS(0.219)PALLPS(0.26)T(0.26)PT(0.26)MPLFPHVLDLLAPLDSSR 92.412 8.42E-08 25936000 843.84 570.11 640.8 249.29 484.91 2950.6 1306.8 975.71 830.74 643.89 TRUE FALSE FALSE 777.0491736 619.387768 664.5486117 248.258504 479.127765 2338.6123 1343.465291 1273.199487 739.6099004 666.2651296 1.166276215 0.92964158 0.997423671 0.372612182 0.71912478 3.510032562 2.016412433 1.910950207 1.11008346 1 9.379952579 -5.283412162 24.99219054 0.98748181 2.432859926 0.710891088 0.458998912 318.311239 362051.7424 0.064129848 0.14350643 5.21E-06 5.283412162 1.445378116 SESGGLGVSMVEYVLSS(ph)SPGDSCLRK ddPTM_HeLa_Curcumin_4h_R1 1 SESGGLGVSMVEYVLSSSPGDSCLRK 26 1 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;H0YEH2 Q5T1Z4 PUM1 Pumilio homolog 1 1 0 SESGGLGVSMVEYVLS(0.19)S(0.694)S(0.115)PGDS(0.001)CLRK 129.37 2.00E-08 51407000 3242.7 2356.6 2243.9 2883.9 2305.6 2910.4 1119.4 859.26 3456.9 2922.8 TRUE FALSE FALSE 2986.036873 2560.294003 2327.060908 2871.967186 2278.107226 2306.750233 1150.807351 1121.244418 3077.686719 3024.367082 0.987326205 0.846555307 0.769437322 0.949609326 0.7532509 0.762721644 0.380511796 0.370736881 1.017630015 1 11.56241754 -4.510320976 0.521274664 0.988959419 2.91E-15 0.860822777 0.084177068 0.772746246 0.165607404 0.017129499 0.441086396 3.09E-05 4.510320976 -0.988959419 down GSPDGS(ph)LQTGKPSAPK ddPTM_HeLa_Curcumin_4h_R1 1 GSPDGSLQTGKPSAPK 16 1 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 "Proline-, glutamic acid- and leucine-rich protein 1" 1 0 GS(0.165)PDGS(0.822)LQT(0.007)GKPS(0.005)APK 62.69 0.01602 59636000 3187.1 2528.3 2535.6 2915.5 3074.7 2991.2 2757.4 2195.7 2884.6 2776.3 TRUE FALSE FALSE 2934.837672 2746.834986 2629.571567 2903.436434 3038.036211 2370.791402 2834.765223 2865.158822 2568.166597 2872.776218 1.021603302 0.956160445 0.915341595 1.010672678 1.057526232 0.825261427 0.98676855 0.99734842 0.893966812 1 11.4882299 -7.258099134 24.25931727 1.01020156 0.963184942 0 0.069270851 302.6646673 2198173.244 0.009589668 0.01147983 5.52E-08 7.258099134 -0.047016617 GSPLVVISQGK ddPTM_HeLa_Curcumin_4h_R1 1 GSPLVVISQGK 11 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 0 0 119.53 0.0021648 696600 676.01 568.85 588.44 598.69 506.45 762.44 473.15 557.77 551.74 609.38 FALSE FALSE TRUE 622.5030952 618.0188593 610.248104 596.2127794 500.4109145 604.3013495 486.4253156 727.8315053 491.2155024 630.5559096 0.987229024 0.980117464 0.967793807 0.945535154 0.793602767 0.958362836 0.771422975 1.154269581 0.779019743 1 9.300480486 -6.261408317 2.792526731 0.991851522 0.908786326 0 0.118831164 0.389788207 6.076256167 0.013586504 0.022754518 5.48E-07 6.261408317 -0.083065197 GSPNANEPPLVFVGK ddPTM_HeLa_Curcumin_4h_R1 1 GSPNANEPPLVFVGK 15 0 H0Y9Q1;P28838-2;P28838 H0Y9Q1 LAP3 Cytosol aminopeptidase 0 0 128.31 0.0014687 771390 187.81 357.84 326.05 427.58 186.05 483.72 225.28 251.37 208.26 211.15 FALSE FALSE TRUE 172.9446403 388.7700951 338.1336998 425.8107873 183.8314753 383.3910194 231.6007505 328.0115558 185.414399 218.4874468 0.791554128 1.779370398 1.547611567 1.948902756 0.841382322 1.754750788 1.060018568 1.501283303 0.84862724 1 7.771406582 -7.273459665 24.75500749 0.901567215 1.478947122 0.438502029 0.316066212 439.3260171 904762.0063 0.051050471 0.058620954 5.33E-08 7.273459665 0.577379908 GSPS(ph)PEKPDVEK ddPTM_HeLa_Curcumin_4h_R1 1 GSPSPEKPDVEK 12 1 Q7Z3Z5;Q93074-3;Q93074;Q93074-2 Q7Z3Z5 TNRC11;MED12 Mediator of RNA polymerase II transcription subunit 12 1 0 GSPS(1)PEKPDVEK 107.37 0.0045076 0 1580.2 1278.8 1338.4 1903.8 1439 1672.7 1695.7 1288.5 1789.2 1624.4 TRUE FALSE FALSE 1455.125503 1389.333774 1388.002281 1895.92258 1421.840865 1325.763165 1743.276778 1681.357718 1592.929236 1680.847779 0.865709269 0.826567278 0.825775123 1.127956144 0.845906978 0.788746715 1.037141376 1.000303382 0.947693929 1 10.71497336 GSPSS(ph)PAGSTPAIPK ddPTM_HeLa_Curcumin_4h_R1 4 GSPSSPAGSTPAIPK 15 0 Q9HCE3 Q9HCE3 ZNF532 Zinc finger protein 532 1 0 GS(0.033)PS(0.167)S(0.561)PAGS(0.12)T(0.12)PAIPK;GS(0.03)PS(0.136)S(0.455)PAGS(0.292)T(0.087)PAIPK;GS(0.001)PS(0.229)S(0.769)PAGSTPAIPK;GS(0.037)PS(0.278)S(0.614)PAGS(0.036)T(0.036)PAIPK ;;; 143.46 0.00050686 46379300 16746.5 14462.2 14259.5 15258.6 14776.2 15992.6 14439.1 6771 16740.2 13947.7 TRUE FALSE FALSE 15420.99685 15712.24813 14787.96961 15195.46396 14600.00347 12675.55449 14844.22229 8835.44673 14903.84194 14432.38154 1.068499805 1.088680207 1.024638212 1.052872938 1.011614294 0.878271854 1.028535883 0.612196033 1.032666847 1 13.81702176 -3.867329671 1.477526078 1.031405437 4.18E-34 0.812556853 0.057941126 1.023234925 0.928471617 0.008361318 2.056838252 0.000135728 3.867329671 -1.031405437 GSPSVAASS(ph)PPAIPK ddPTM_HeLa_Curcumin_4h_R1 1 GSPSVAASSPPAIPK 15 0 H0YM74;Q92610 H0YM74 ZNF592 Zinc finger protein 592 1 0 GSPSVAAS(0.11)S(0.89)PPAIPK 120.87 0.0012577 9483500 4677.1 3460.9 3895.2 3971 3710.7 4505.9 2907.6 2371.7 4880.6 3854.1 TRUE FALSE FALSE 4306.9026 3760.044775 4039.559539 3954.569054 3666.452326 3571.325548 2989.179431 3094.820412 4345.210391 3988.029688 1.079957507 0.942832694 1.01292113 0.991609733 0.919364351 0.895511274 0.749537908 0.776027426 1.0895632 1 11.96146043 -5.084516196 0.777615133 1.032338302 0.709865201 0.850451151 0.042147658 0.295760904 0.239495808 0.007388539 0.064873375 8.23E-06 5.084516196 -0.322473101 KFELLPTPPLS(ph)PSRR ddPTM_HeLa_Curcumin_4h_R1 1 KFELLPTPPLSPSRR 15 2 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1 H0YBT0 MYC Myc proto-oncogene protein 1 0 KFELLPTPPLS(0.901)PS(0.098)RR 86.189 0.0077877 75851000 5781.8 4205.1 4950 4767.4 4838.9 5872 2679.4 897.35 5494.5 4728.4 TRUE FALSE FALSE 5324.164429 4568.570106 5133.451354 4747.673762 4781.199278 4654.081009 2754.576753 1170.947884 4891.767097 4892.711548 1.088182775 0.933750143 1.04920376 0.970356359 0.977208493 0.951227344 0.562995943 0.239324937 0.999806968 1 12.25641852 -4.50886519 1.571354741 1.028103494 0.120046948 0.965880617 0.046626297 0.085431736 0.276918741 0.007454055 0.102532753 3.10E-05 4.50886519 -0.908056546 down GSPVSEIGWETPPPES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 GSPVSEIGWETPPPESPR 18 0 A0A3B3ITC2;Q13884-2;Q13884 A0A3B3ITC2 SNTB1 Beta-1-syntrophin 1 0 GSPVSEIGWETPPPES(1)PR 208.59 2.04E-12 8743800 887.7 680.14 586.52 705.28 896.09 983.41 779.38 643.68 910.45 789.65 TRUE FALSE FALSE 817.4376083 738.928271 608.2569472 702.3617382 885.404712 779.4396807 801.2473052 839.9350689 810.5759128 817.0902787 1.000425081 0.904341038 0.744418289 0.859588905 1.083606959 0.953921128 0.980610498 1.02795871 0.992027361 1 9.674351678 -3.098534901 16.32833438 0.971835545 0.950076111 0 0.093237502 0 0 0.013094673 0 0.000797012 3.098534901 -0.021759434 GSPVSSPQNS(ph)PGTQR ddPTM_HeLa_Curcumin_4h_R1 2 GSPVSSPQNSPGTQR 15 0 A0A2R8YE75;A0A2R8Y6F3;Q9P2P5 A0A2R8YE75 HECW2 E3 ubiquitin-protein ligase HECW2 1 0 GSPVS(0.003)S(0.078)PQNS(0.86)PGT(0.059)QR;GSPVSS(0.006)PQNS(0.893)PGT(0.102)QR ; 145.79 0.00048442 3901800 1257.37 1005.85 987.79 1077.72 1010.24 886.11 824.78 733.25 1214.4 1203.88 TRUE FALSE FALSE 1157.847838 1092.791192 1024.398366 1073.26068 998.1935478 702.3207975 847.921107 956.8145495 1081.183358 1245.71474 0.929464668 0.877240316 0.822337838 0.861562158 0.801301867 0.563789425 0.680670365 0.768084794 0.867922104 1 10.28275802 -6.272002614 0.530834525 0.984053664 0.655022144 0.624326955 0.072447625 0.340123436 0.183176369 0.017257357 0.048705894 5.35E-07 6.272002614 -0.32903152 GSQEDDPAATQRPPS(ph)NGGAK ddPTM_HeLa_Curcumin_4h_R1 1 GSQEDDPAATQRPPSNGGAK 20 1 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 0 GSQEDDPAAT(0.019)QRPPS(0.981)NGGAK 75.43 0.0018449 5278300 1796.7 1690.2 1750.5 1842.4 2115.4 2002.3 1987.1 957.48 1654.8 1341.7 TRUE FALSE FALSE 1654.489299 1836.293357 1815.37507 1834.776637 2090.175237 1587.000409 2042.852678 1249.411244 1473.27258 1388.323975 1.191717012 1.322669196 1.307601902 1.321576714 1.50553853 1.143105239 1.471452424 0.899942136 1.061187883 1 10.43912855 -8.221270718 0.775008015 1.021932423 1.294651674 0.259465309 0.162367673 0.461910184 0.598482298 0.056438184 0.03481683 6.01E-09 8.221270718 0.272719251 GSQPPPAAESQS(ph)SLRR ddPTM_HeLa_Curcumin_4h_R1 1 GSQPPPAAESQSSLRR 16 1 O43491;O43491-4;E9PHY5;E9PK52;O43491-3;O43491-2;E9PII3;A0A2R8Y5B3;E9PJP4;E9PQD2;E9PIG0;E9PRG1;E9PQN0 O43491 EPB41L2 Band 4.1-like protein 2 1 0 GSQPPPAAES(0.028)QS(0.891)S(0.081)LRR 84.113 0.0045943 6018500 7621 7251.2 7558.1 7405.3 8226 8718.6 7532.2 4868.7 7117 7564.1 TRUE FALSE FALSE 7017.789808 7877.961417 7838.209835 7374.658831 8127.910323 6910.264081 7743.53326 6353.144217 6336.282906 7826.951912 0.89661849 1.006517161 1.001438353 0.942213382 1.038451547 0.88288061 0.989342128 0.811700939 0.809546676 1 12.93423487 -4.254297862 24.50166719 0.959886057 0.811700847 0.273753407 0.067377487 489.5928574 1679676.355 0.007170785 0.096296967 5.57E-05 4.254297862 -0.148185211 GSS(ph)FEMTDDDSAIR ddPTM_HeLa_Curcumin_4h_R1 1 GSSFEMTDDDSAIR 14 0 H7BXY3;Q7L2E3-3;Q7L2E3;Q7L2E3-2 H7BXY3 DHX30 Putative ATP-dependent RNA helicase DHX30 1 0 GS(0.015)S(0.985)FEMTDDDSAIR 193.11 4.95E-06 10505000 1628.6 1250.2 1344.2 1392.8 1250.7 1520 1569.7 968.79 1716.9 1702.7 TRUE FALSE FALSE 1499.694592 1358.261717 1394.017234 1387.036963 1235.786219 1204.734866 1613.741557 1264.169611 1528.560365 1761.868698 0.851195434 0.770921079 0.791215166 0.787253309 0.701406535 0.683782434 0.915926118 0.717516358 0.867579047 1 10.7828907 -8.222013494 0.544250982 1.000051651 0.758404714 0.423664913 0.072415733 0.347649782 0.230751215 0.036555852 0.018680507 6.00E-09 8.222013494 -0.241646937 GSS(ph)FQSGRDDTWR ddPTM_HeLa_Curcumin_4h_R1 2 GSSFQSGRDDTWR 13 1 Q96KP1 Q96KP1 EXOC2 Exocyst complex component 2 1 0 GS(0.162)S(0.745)FQS(0.092)GRDDT(0.001)WR;GS(0.046)S(0.91)FQS(0.044)GRDDTWR ; 65.956 0.01818 161597000 4100.1 2699.6 3159 3285.6 3183.3 3232.8 2596.4 1483.41 3786.7 3428.7 TRUE FALSE FALSE 3775.572759 2932.941395 3276.075319 3272.005058 3145.341227 2562.280839 2669.247996 1935.69488 3371.308484 3547.84707 1.064187008 0.826682024 0.923398121 0.922250873 0.886549269 0.72220724 0.752357118 0.545597046 0.950240644 1 11.79272811 -3.685976485 0.361155409 1.033046463 5.70E-16 0.79096607 0.066027979 2.486732505 0.165228319 0.020285327 1.214663767 0.000206074 3.685976485 -1.033046463 GSS(ph)GSPAHAESYSSGGGGQQK ddPTM_HeLa_Curcumin_4h_R1 2 GSSGSPAHAESYSSGGGGQQK 21 0 P15408 P15408 FOSL2 Fos-related antigen 2 1 0 GS(0.112)S(0.444)GS(0.444)PAHAESYSSGGGGQQK;GS(0.156)S(0.73)GS(0.114)PAHAESYSSGGGGQQK ; 123.58 6.99E-06 19622300 9574.7 6227.4 6592 6994.6 11378.3 19610.1 8894.7 4314.2 11688.4 6987.5 TRUE FALSE FALSE 8816.852392 6765.668707 6836.305319 6965.658199 11242.6212 15542.74421 9144.261343 5629.57972 10406.21176 7230.315105 1.219428512 0.935736356 0.945505862 0.963396214 1.554928249 2.149663463 1.264711318 0.778607798 1.439247337 1 12.81984281 -5.759091754 24.99971469 1.070101466 1.475579134 0.195856761 0.346318628 67.63291384 720202.6736 0.048841169 0.094088051 1.74E-06 5.759091754 0.405477668 GSS(ph)LKIEER ddPTM_HeLa_Curcumin_4h_R1 1 GSSLKIEER 9 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1;C9J813 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 1 0 GS(0.004)S(0.996)LKIEER 163.46 0.0043087 18293000 4254.6 3114.7 3104.2 3421.5 3058.4 4337.3 3722.7 3377.3 3931.5 3334.7 TRUE FALSE FALSE 3917.843921 3383.920789 3219.244383 3407.34274 3021.930578 3437.695089 3827.148943 4407.023223 3500.224286 3450.580577 1.135415862 0.980681573 0.932957313 0.987469402 0.875774528 0.996265704 1.109131886 1.277183107 1.01438706 1 11.75262341 -4.358743221 2.830514207 1.027695988 1.296611901 0.577689605 0.070649327 0.255850629 3.114243325 0.012625226 0.13997197 4.38E-05 4.358743221 0.268915912 GSS(ph)LSGTDDGAQEVVKDILEDVVTSAIK ddPTM_HeLa_Curcumin_4h_R1 1 GSSLSGTDDGAQEVVKDILEDVVTSAIK 28 1 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 0 GS(0.058)S(0.626)LS(0.206)GT(0.111)DDGAQEVVKDILEDVVTSAIK 96.382 7.63E-08 4184500 1347.7 920.82 1276.4 1527.6 1261.3 1368.6 1118.7 586.9 1701.2 1344.6 TRUE FALSE FALSE 1241.028123 1000.411578 1323.704507 1521.279196 1246.259821 1084.736933 1150.087711 765.8431082 1514.582616 1391.32475 0.891975883 0.719035278 0.951398663 1.093403388 0.895736111 0.779643238 0.826613421 0.550441662 1.088590292 1 10.44224348 -3.781707784 0.86286296 0.937705019 5.95E-18 0.550406465 0.107362096 2.622762314 0.816824577 0.016212705 2.835584679 0.000165307 3.781707784 -0.937705019 GSS(ph)PGPRPVEGTPASR ddPTM_HeLa_Curcumin_4h_R1 1 GSSPGPRPVEGTPASR 16 1 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 0 GS(0.043)S(0.957)PGPRPVEGTPASR 70.334 0.010793 940110000 4459.7 3893 3249.2 3938 3750.9 4809.8 3350.5 2090.9 4269 3901 TRUE FALSE FALSE 4106.710039 4229.493573 3369.61821 3921.705599 3706.172967 3812.193262 3444.506013 2728.405785 3800.701381 4036.55946 1.017378805 1.047796673 0.834774823 0.971546595 0.918151461 0.944416477 0.853327208 0.675923596 0.941569527 1 11.97891043 -3.240916469 0.514816585 1.003445986 4.21E-19 0.674118229 0.059109846 3.764350329 0.311195728 0.010821595 2.893874566 0.000574227 3.240916469 -1.003445986 GSS(ph)PLGPAGLGAEEPAAGPQLPSWLQPER ddPTM_HeLa_Curcumin_4h_R1 1 GSSPLGPAGLGAEEPAAGPQLPSWLQPER 29 0 O43482;H0YKL4 O43482 OIP5 Protein Mis18-beta;Protein yippee-like 1 0 GS(0.458)S(0.542)PLGPAGLGAEEPAAGPQLPSWLQPER 81.455 3.65E-06 6714700 1011.9 1075.4 1119.2 1206.8 1041 1292.2 1012.4 779.92 1194.4 1117.9 TRUE FALSE FALSE 931.8070472 1168.352784 1160.678537 1201.806581 1028.586755 1024.183154 1040.805219 1017.714018 1063.377308 1156.746942 0.805540965 1.010033173 1.003398837 1.038953757 0.889206375 0.885399491 0.899769156 0.879806966 0.919282576 1 10.17585757 GSS(ph)PLPTATTPKPLIPTEASIR ddPTM_HeLa_Curcumin_4h_R1 1 GSSPLPTATTPKPLIPTEASIR 22 1 Q9BUK6-2;Q9BUK6;A0A3B3IUD2;Q9BUK6-7;Q9BUK6-3 Q9BUK6-2 MSTO1 Protein misato homolog 1 1 0 GS(0.286)S(0.707)PLPT(0.006)AT(0.001)TPKPLIPTEASIR 87.808 0.00020141 46139000 1043.7 893.02 1109.6 1130.2 738.21 1874 1636.5 884.02 1200.7 890.42 TRUE FALSE FALSE 961.0900437 970.2086696 1150.722752 1125.523532 729.4073279 1485.311276 1682.415786 1153.553628 1068.986214 921.3620287 1.043118789 1.053015687 1.248936592 1.221586626 0.791662023 1.612082145 1.826009465 1.252009083 1.160223865 1 9.847624332 -5.245706042 24.66109964 1.043178461 1.589631243 0.604312671 0.179848456 288.7157656 452544.2392 0.023156067 0.058806926 5.68E-06 5.245706042 0.546452782 GSS(ph)PT(ph)PPCSPVQPSK ddPTM_HeLa_Curcumin_4h_R1 1 GSSPTPPCSPVQPSK 15 0 H0YBY0;E7EPX0;E7EVJ4;Q9NUL3-4;Q9NUL3-6;Q9NUL3-8;Q9NUL3-3;Q9NUL3-7;Q9NUL3-2;Q9NUL3 H0YBY0 STAU2 Double-stranded RNA-binding protein Staufen homolog 2 2 0 GS(0.259)S(0.729)PT(0.825)PPCS(0.183)PVQPS(0.003)K 111.81 0.0091806 6841500 4857.3 4075.4 3673.9 4268.6 4018.5 4442.7 2867.7 3520.9 4200.7 3920.9 TRUE FALSE FALSE 4472.83958 4427.659416 3810.057966 4250.937664 3970.582012 3521.23394 2948.159944 4594.406202 3739.89372 4057.150983 1.102458252 1.091322318 0.939096914 1.047764227 0.97866262 0.867908036 0.726657686 1.132421796 0.921802944 1 11.98625128 -5.502143906 3.244245586 1.043822476 0.891969065 0.130568523 0.109303755 0.226075786 4.869463969 0.014351173 0.03285162 3.15E-06 5.502143906 -0.151853411 GSS(ph)TPTKGIENK ddPTM_HeLa_Curcumin_4h_R1 1 GSSTPTKGIENK 12 1 O60271-3;O60271;A0A087X2D8;O60271-5;O60271-9;O60271-4;O60271-2;H0YBE9 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 GS(0.039)S(0.889)T(0.072)PTKGIENK 187.78 0.00013904 20998000 4028.1 2937.6 3238 3673.2 2881.6 3931.7 2702.7 2644.5 4145.3 3295.9 TRUE FALSE FALSE 3709.271635 3191.513054 3358.003128 3658.001272 2847.238802 3116.221101 2778.530488 3450.795876 3690.570961 3410.43228 1.087625066 0.935808951 0.984626831 1.072591675 0.834861557 0.913731998 0.814715045 1.011835331 1.082141693 1 11.7357389 -5.764616266 24.99999859 1.030766031 0.889562769 0.492365478 0.066214182 49.48190174 389394.0852 0.009582446 0.017911382 1.72E-06 5.764616266 -0.141203262 GSS(ph)YSSIPK ddPTM_HeLa_Curcumin_4h_R1 3 GSSYSSIPK 9 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 0 GS(0.003)S(0.617)YS(0.095)S(0.286)IPK;GS(0.003)S(0.888)YS(0.032)S(0.076)IPK;GS(0.001)S(0.997)YS(0.001)S(0.001)IPK ;; 134.23 0.0032545 45792000 18942.8 15713.4 18398.5 18785.1 18479.6 22790.7 19431.8 25385.6 19142 18219.9 TRUE FALSE FALSE 17443.45739 17071.59628 19080.36459 18707.37223 18259.24284 18063.65192 19977.00401 33125.55258 17042.17049 18853.04017 0.925233131 0.905508933 1.012057707 0.992273504 0.968503895 0.958129392 1.059617114 1.757040365 0.903948135 1 14.20250957 -4.254799073 3.323980416 0.965537729 1.870170202 0.977099365 0.03644802 0.03441204 0.609598845 0.005246508 0.079910167 5.56E-05 4.254799073 0.904632473 GSSAAASPGS(ph)PPPGR ddPTM_HeLa_Curcumin_4h_R1 4 GSSAAASPGSPPPGR 15 0 Q86UX6 Q86UX6 STK32C Serine/threonine-protein kinase 32C 1 0 GSSAAASPGS(1)PPPGR;GSSAAAS(0.005)PGS(0.995)PPPGR;GSSAAAS(0.011)PGS(0.989)PPPGR;GSSAAAS(0.084)PGS(0.916)PPPGR ;;; 158.14 0.00033931 91506300 5732.46 5564.39 5683.9 6073.35 5473.49 5574.44 4533.01 3190.59 6588.77 5780.88 TRUE FALSE FALSE 5278.729742 6045.351077 5894.550334 6048.220087 5408.222207 4418.238307 4660.194061 4163.386203 5865.998415 5981.76515 0.882470242 1.010629961 0.985419886 1.011109586 0.904118111 0.738617815 0.779066704 0.696012983 0.980646727 1 12.54635555 -5.342990174 3.511610415 0.956369279 0.73984533 0.857862696 0.043146703 0.087091495 2.054977558 0.007907846 0.019269068 4.54E-06 5.342990174 -0.216523949 GSSANASKWS(ph)PPQNYK ddPTM_HeLa_Curcumin_4h_R1 1 GSSANASKWSPPQNYK 16 1 H3BRF9;Q96K21-2;Q96K21;H3BRM1;Q96K21-3 H3BRF9;Q96K21-3 ZFYVE19 Abscission/NoCut checkpoint regulator 1 0 GSSANAS(0.003)KWS(0.996)PPQNYK 73.11 0.0091408 109660000 2984.2 2284.6 2303.7 2596.9 1929.3 3311.8 2092.5 2061 3385.1 2680.4 TRUE FALSE FALSE 2747.997421 2482.070644 2389.077149 2586.154716 1906.294358 2624.895348 2151.209918 2689.389412 3013.762999 2773.5437 0.9907893 0.894909514 0.861380748 0.932436981 0.687313619 0.9464049 0.77561782 0.969658207 1.086610966 1 11.43751474 -7.145415172 2.142299947 0.997168134 0.856284906 0.42265957 0.083664728 0.211915577 1.868685118 0.0125204 0.015498991 7.15E-08 7.145415172 -0.140883229 TPADRGPS(ph)PAPAPAASPQPGSR ddPTM_HeLa_Curcumin_4h_R1 1 TPADRGPSPAPAPAASPQPGSR 22 1 Q8IX07 Q8IX07 ZFPM1 Zinc finger protein ZFPM1 1 0 T(0.005)PADRGPS(0.993)PAPAPAAS(0.002)PQPGSR 65.836 0.0015246 9757200 979.47 900.16 861.07 807.06 633.35 810.55 562.12 162.11 1039.2 906.38 TRUE FALSE FALSE 901.943916 977.9658194 892.9820117 803.7205996 625.7977149 642.4327932 577.8915743 211.5365927 925.20236 937.8766375 0.961687156 1.042744621 0.95213163 0.856957693 0.667249497 0.684986455 0.616170135 0.225548419 0.9864862 1 9.873254362 -4.508741546 0.561558124 0.992822894 1.04E-17 0.914934053 0.070293743 0.580110692 0.14607632 0.013538536 0.353870994 3.10E-05 4.508741546 -0.992822894 down GSSDGRGS(ph)DS(ph)ESDLPHR ddPTM_HeLa_Curcumin_4h_R1 1 GSSDGRGSDSESDLPHR 17 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 2 0 GS(0.064)S(0.035)DGRGS(0.888)DS(0.651)ES(0.362)DLPHR 75.319 0.0099572 13254000 4042.4 3238.9 3399.2 3333.3 4368.9 5715.8 4006.5 3701.6 4684.8 3846.4 TRUE FALSE FALSE 3722.439774 3518.856084 3525.177342 3319.507688 4316.803721 4530.27865 4118.911607 4830.2008 4170.889161 3980.062114 0.935271779 0.884120896 0.885709128 0.834034141 1.084607124 1.138243203 1.034886263 1.213599351 1.047945746 1 11.95857523 -5.603233474 7.738602566 0.946298503 1.118184707 0.6252176 0.070679625 0.126831329 10.54567975 0.010041083 0.020143853 2.49E-06 5.603233474 0.171886203 GSSDGRGS(ph)DSESDLPHR ddPTM_HeLa_Curcumin_4h_R1 1 GSSDGRGSDSESDLPHR 17 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 GSSDGRGS(0.965)DS(0.031)ES(0.003)DLPHR 105.39 0.00064648 19857000 4281.9 3185 3443.5 3347.3 4937.1 5603.2 3696.1 3869.3 4613.2 3710.9 TRUE FALSE FALSE 3942.983097 3460.297208 3571.119139 3333.44976 4878.228307 4441.033159 3799.802618 5049.031758 4107.143502 3839.853499 1.026857691 0.901153445 0.930014424 0.868118995 1.270420423 1.156563176 0.989569685 1.314902186 1.069609427 1 11.90683555 -5.758254976 24.99999258 0.987759728 1.167178511 0.527601536 0.098825991 58.02015491 455494.91 0.013832341 0.026763804 1.74E-06 5.758254976 0.179418783 WNS(ph)IEER ddPTM_HeLa_Curcumin_4h_R1 2 WNSIEER 7 0 Q9UNE7;H3BS86;H3BTA3;Q9UNE7-2;H3BUD0 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 0 WNS(1)IEER;WNS(1)IEER ; 131.52 0.0066094 31105000 3135.2 2825.7 2753.5 2959.8 3245.9 4807.7 4303.3 29189 3571.2 2574.4 TRUE FALSE FALSE 2887.045612 3069.940917 2855.547132 2947.553132 3207.194762 3810.528826 4424.039016 38088.59173 3179.448295 2663.860208 1.083782701 1.152440698 1.071958327 1.106496926 1.203965115 1.430453751 1.660762454 14.29826971 1.193549228 1 11.37930266 -4.260405663 5.068360524 1.10065579 14.93152683 0.999069746 0.119878305 0.004534269 0.37069472 0.022828956 0.218590436 5.49E-05 4.260405663 13.83087104 up GSSEQAES(ph)DNMDVPPEDDSKEGAGEQK ddPTM_HeLa_Curcumin_4h_R1 1 GSSEQAESDNMDVPPEDDSKEGAGEQK 27 1 Q12906;Q12906-7;Q12906-5;Q12906-4;Q12906-2;Q12906-6;Q12906-3;K7EKJ9;K7ER69;K7EM82;K7EJ09 Q12906 ILF3 Interleukin enhancer-binding factor 3 1 0 GS(0.023)S(0.023)EQAES(0.952)DNMDVPPEDDS(0.003)KEGAGEQK 71.903 0.00015266 10908000 1356.6 1181.3 1715.5 1239 1621.8 1735.6 1633.3 1452.8 1268.9 1049.6 TRUE FALSE FALSE 1249.223679 1283.406308 1779.077939 1233.873346 1602.461094 1375.616996 1679.126002 1895.752032 1129.704845 1086.073522 1.150220177 1.181693764 1.638082416 1.13608639 1.475462813 1.266596568 1.546051873 1.745509852 1.040173452 1 10.08490605 -1 0.136267865 0.875147935 3.563187761 0.621093876 0.153616746 33.77778525 0.306491868 0.431042346 17.66343218 0.1 1 2.688039826 GSSES(ph)PFDLTTK ddPTM_HeLa_Curcumin_4h_R1 1 GSSESPFDLTTK 12 0 H9KVD4;E7EUL6;A0A0C3SFZ7;Q03112-8;Q03112-5;Q03112-6;Q03112-1;Q03112-4;Q03112;Q03112-3 H9KVD4 MECOM MDS1 and EVI1 complex locus protein EVI1 1 0 GSSES(0.999)PFDLT(0.001)TK 159.66 0.00023112 7705700 1877.3 1381.8 1434.3 1734.6 1837.7 2705.1 2351.9 680.91 2109.2 1361.5 TRUE FALSE FALSE 1728.709724 1501.236635 1487.45642 1727.422685 1815.786628 2144.031767 2417.887984 888.5163245 1877.826037 1408.812024 1.227069116 1.065604644 1.055823201 1.226155552 1.288877861 1.521872139 1.716260185 0.630684797 1.332914545 1 10.46026341 -5.951248247 2.737679724 1.103047633 1.337762468 0.046845548 0.276078156 0.402906402 6.133192843 0.038610508 0.073527213 1.12E-06 5.951248247 0.234714835 GSSGDSDS(ph)PGSSSLSLTR ddPTM_HeLa_Curcumin_4h_R1 2 GSSGDSDSPGSSSLSLTR 18 0 H0Y507;Q5TCZ1-2;Q5TCZ1-3;Q5TCZ1 H0Y507 SH3PXD2A SH3 and PX domain-containing protein 2A 1 0 GSSGDSDS(1)PGSSSLSLTR;GSSGDSDS(0.653)PGS(0.329)S(0.016)S(0.002)LSLTR ; 237.34 1.23E-25 32654000 5266 3975.9 3727 4847.9 4659.2 5608.1 4023.4 1909.18 5389.8 4439.3 TRUE FALSE FALSE 4849.190543 4319.55908 3865.125899 4827.840674 4603.642083 4444.916844 4136.285776 2491.280193 4798.552425 4593.565345 1.055648539 0.94034998 0.841421773 1.051000761 1.002193664 0.967639842 0.900452147 0.542341298 1.044624832 1 12.16539864 -4.035235631 1.545220458 1.006181274 0.128053952 0.821101003 0.0618734 0.603241314 0.857234538 0.009540572 0.944394921 9.22E-05 4.035235631 -0.878127322 NMTVEQLLTGSPT(ph)SPTVEPEKPTR ddPTM_HeLa_Curcumin_4h_R1 2 NMTVEQLLTGSPTSPTVEPEKPTR 24 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 0 NMTVEQLLT(0.017)GS(0.028)PT(0.593)S(0.246)PT(0.115)VEPEKPTR;NMTVEQLLT(0.001)GS(0.164)PT(0.413)S(0.413)PT(0.008)VEPEKPTR ; 107.7 1.86E-06 47693000 2578.25 2350.9 2246.51 2486.09 2053.01 2950.03 2880.51 9060.73 2800.18 2375.2 TRUE FALSE FALSE 2374.178792 2554.101321 2329.767637 2475.803218 2028.529197 2338.160524 2961.329358 11823.30487 2493.00726 2457.738023 0.966001571 1.039208124 0.947931641 1.007350334 0.825364289 0.951346524 1.204900331 4.810644892 1.014350283 1 11.26311543 -4.260396887 4.568911906 0.975985095 5.058798669 0.997611266 0.056115335 0.006355507 0.343469612 0.008013744 0.083044117 5.49E-05 4.260396887 4.082813574 up LLS(ph)SNEDDANILSSPTDR ddPTM_HeLa_Curcumin_4h_R1 3 LLSSNEDDANILSSPTDR 18 0 H0YEG1;F5GY88;A0A0B4J1W0;O75448-2;O75448 H0YEG1 MED24 Mediator of RNA polymerase II transcription subunit 24 1 0 LLS(0.5)S(0.5)NEDDANILSSPTDR;LLS(0.5)S(0.5)NEDDANILSSPTDR;LLS(0.769)S(0.231)NEDDANILSSPTDR ;; 278.32 4.11E-67 55166300 2838.75 2003.48 2539.79 2595.74 2345.17 2806.75 3901.67 9987.5 2048.22 2880.09 TRUE FALSE FALSE 2614.059942 2176.651884 2633.916852 2584.999516 2317.205379 2224.598411 4011.140359 13032.64277 1823.53539 2980.172913 0.877150427 0.730377715 0.883813432 0.867399171 0.777540581 0.746466221 1.345942157 4.37311631 0.611889123 1 11.54118032 -4.260350103 3.352872892 0.895669341 4.839091379 0.985916528 0.126657884 0.021571344 0.396348248 0.015120425 0.218129977 5.49E-05 4.260350103 3.943422038 up GSSPSIRPIQGS(ph)QGSSSPVEKEVVEATDSR ddPTM_HeLa_Curcumin_4h_R1 1 GSSPSIRPIQGSQGSSSPVEKEVVEATDSR 30 2 Q92560;F8W6N3;H0Y8E8 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 0 GS(0.001)S(0.002)PS(0.004)IRPIQGS(0.382)QGS(0.382)S(0.114)S(0.114)PVEKEVVEAT(0.001)DSR 46.63 0.0067492 13671000 1914.2 1540.6 1506.2 1756.8 1463 2476.6 1797 1890.6 2031.6 1725.2 TRUE FALSE FALSE 1762.68905 1673.762599 1562.021097 1749.530827 1445.554681 1962.925243 1847.418984 2467.035237 1808.738563 1785.150572 0.987417576 0.937603038 0.875008037 0.980046644 0.809766248 1.099585253 1.034881322 1.381975995 1.013213446 1 10.80183005 -3.86844779 1.39871043 0.971214827 2.009808565 0.746158465 0.073366594 1.23139072 1.019540337 0.010377793 2.348676426 0.000135379 3.86844779 1.038593738 GSSPT(ph)PPCS(ph)PVQPSK ddPTM_HeLa_Curcumin_4h_R1 2 GSSPTPPCSPVQPSK 15 0 H0YBY0;E7EPX0;E7EVJ4;Q9NUL3-4;Q9NUL3-6;Q9NUL3-8;Q9NUL3-3;Q9NUL3-7;Q9NUL3-2;Q9NUL3 H0YBY0 STAU2 Double-stranded RNA-binding protein Staufen homolog 2 2 0 GS(0.006)S(0.12)PT(0.876)PPCS(0.996)PVQPS(0.002)K;GS(0.002)S(0.036)PT(0.962)PPCS(1)PVQPSK ; 148.18 0.0020778 31516200 8873.6 7379 8270 8540.6 8574.4 11806.4 8693.9 9501.7 8745 7535.8 TRUE FALSE FALSE 8171.245197 8016.80788 8576.493475 8505.26126 8472.15588 9357.619554 8937.827436 12398.72459 7785.695379 7797.668489 1.04790877 1.028103194 1.099879212 1.090744146 1.086498598 1.200053525 1.14621793 1.590055362 0.998464527 1 12.92882711 -1 0.681934848 1.032341698 59.23978049 0.90664691 0.050434129 46.98230999 0.249622733 0.008091436 4162.923221 0.1 1 58.20743879 GSSS(ph)DSTAGVKE ddPTM_HeLa_Curcumin_4h_R1 1 GSSSDSTAGVKE 12 1 Q86TU7 Q86TU7 SETD3 Histone-lysine N-methyltransferase setd3 1 0 GS(0.006)S(0.024)S(0.97)DSTAGVKE 109 0.0092585 9491300 2814.8 2589.2 2462 2592.1 2710.8 3456.3 2250.1 1930.6 2690.8 2359.5 TRUE FALSE FALSE 2592.00561 2812.998911 2553.243886 2581.374577 2678.47548 2739.424419 2313.23175 2519.231053 2395.625972 2441.492449 1.061648014 1.152163674 1.045771772 1.057293697 1.097064822 1.122028626 0.947466272 1.031840608 0.981213754 1 11.2535476 -1.028004136 21.5602933 1.045192843 0.004324924 0 0.060265428 0 0 0.007949388 0 0.093755308 1.028004136 -1.04086792 GSSS(ph)SSPEHSASSDSTK ddPTM_HeLa_Curcumin_4h_R1 1 GSSSSSPEHSASSDSTK 17 0 Q9P275;A0A075B784 Q9P275 USP36 Ubiquitin carboxyl-terminal hydrolase 36;Ubiquitin carboxyl-terminal hydrolase 1 0 GS(0.144)S(0.048)S(0.269)S(0.269)S(0.269)PEHSASSDSTK 66.308 0.011191 25811000 2401.1 2710.3 1769.5 1917.5 3904.7 5715.7 2379.7 1370.3 3301 1825.2 TRUE FALSE FALSE 2211.050401 2944.566255 1835.079227 1909.565893 3858.139003 4530.199391 2446.467977 1788.098162 2938.888559 1888.625564 1.170719302 1.559105368 0.971647986 1.011087602 2.042828963 2.398675247 1.295369513 0.94677219 1.55609911 1 10.88312099 -5.777160048 25 1.108942117 1.696070211 0.198360453 0.422209764 213.1690409 338994.628 0.060599591 0.11011283 1.67E-06 5.777160048 0.587128093 GSSSQAPASK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 GSSSQAPASKK 11 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 0 1 ; GSSSQAPASK(1)K;GSSSQAPASK(1)K 187.31 9.53E-13 5968600 3880 5110.5 3825.2 2493.71 2534.98 4500.9 2515.65 2270.38 2600.16 3764.5 FALSE TRUE FALSE 3572.893906 5552.228848 3966.965277 2483.391689 2504.752019 3567.362604 2586.232368 2962.60841 2314.928953 3895.316095 0.917228235 1.425360282 1.018393676 0.637532777 0.643016371 0.915808247 0.66393389 0.760556612 0.594285264 1 11.92752469 -6.271599937 24.24340704 1.006062064 0.726961234 0.301797508 0.202301728 345.4652022 824290.0802 0.025011686 0.038491894 5.35E-07 6.271599937 -0.27910083 GSSSSS(ph)PEHSASSDSTK ddPTM_HeLa_Curcumin_4h_R1 1 GSSSSSPEHSASSDSTK 17 0 Q9P275;A0A075B784 Q9P275 USP36 Ubiquitin carboxyl-terminal hydrolase 36;Ubiquitin carboxyl-terminal hydrolase 1 0 GSSSS(0.002)S(0.998)PEHSASSDSTK 284.53 2.87E-66 5740400 2156.8 2056.2 1557 1374.7 3338.6 4871.7 1818.5 793.72 2399.7 1439.3 TRUE FALSE FALSE 1986.087004 2233.928766 1614.70379 1369.011856 3298.789376 3861.254505 1869.522216 1035.721574 2136.458914 1489.315568 1.333556868 1.499970063 1.084191843 0.919222148 2.214970048 2.592636905 1.255289514 0.695434599 1.434523992 1 10.54043376 -5.777749534 24.96900263 1.168715371 1.723065841 0.171021287 0.507777298 283.9603728 434710.8805 0.077038992 0.139942066 1.67E-06 5.777749534 0.55435047 GSTDNLMDDIER ddPTM_HeLa_Curcumin_4h_R1 4 GSTDNLMDDIER 12 0 P50990-2;P50990;P50990-3 P50990-2 CCT8 T-complex protein 1 subunit theta 0 0 ;;; ;;; 255.19 8.73E-52 41530600 9208.3 7341.85 8141.91 7095.39 7664.02 9672.8 7742.96 7544.01 9067.68 7790.05 FALSE FALSE TRUE 8479.453338 7976.446799 8443.656347 7066.031156 7572.631567 7666.552245 7960.206618 9844.143921 8072.97819 8060.753658 1.051942994 0.98954107 1.047502095 0.876596837 0.939444609 0.951096209 0.987526348 1.221243613 1.00151655 1 12.97669902 -4.259108653 24.46409108 1.001904602 1.221243718 0.638330704 0.052087545 91.61555476 961541.1443 0.008160731 0.073169067 5.51E-05 4.259108653 0.219339116 GSTDS(ph)LDSLSSR ddPTM_HeLa_Curcumin_4h_R1 1 GSTDSLDSLSSR 12 0 Q9ULJ8;Q9ULJ8-4;Q9ULJ8-5;Q9ULJ8-3 Q9ULJ8 PPP1R9A Neurabin-1 1 0 GS(0.002)T(0.006)DS(0.99)LDS(0.003)LSSR 109.6 0.0056986 9063900 2715.8 2741.3 2378.4 2830.4 2115.5 2335.5 1702.3 1224.6 2802.8 2041.1 TRUE FALSE FALSE 2500.841564 2978.245757 2466.545596 2818.688555 2090.274044 1851.090973 1750.061956 1597.974903 2495.339852 2112.028073 1.18409485 1.410135497 1.167856445 1.334588584 0.989699934 0.876451879 0.828616806 0.756606848 1.181489907 1 11.0444133 -5.362823856 2.805815685 1.138389626 0.812511107 0.654878408 0.121241959 0.176196606 2.670783376 0.021176798 0.053958951 4.34E-06 5.362823856 -0.325878519 GSTEGSESYEEDPYLVVNPNYLLED ddPTM_HeLa_Curcumin_4h_R1 2 GSTEGSESYEEDPYLVVNPNYLLED 25 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 0 0 ; ; 87.208 5.11E-05 5798300 3344.1 2983.9 3275.4 3532.8 3448.2 4230.1 3420.9 2995 3404.3 3038.3 FALSE FALSE TRUE 3079.410956 3241.81502 3396.789205 3518.18221 3407.082467 3352.729577 3516.881247 3908.161713 3030.856807 3143.880699 0.979493579 1.031150775 1.080444689 1.119057161 1.083718752 1.066430281 1.118643353 1.24310115 0.964049561 1 11.61833076 -1 0.249835765 0.980253408 2.452875752 0.798641508 0.035004855 16.44775447 0.205200408 0.021596395 10.29799015 0.1 1 1.472622344 T(ph)TSREEVDEAASTLTR ddPTM_HeLa_Curcumin_4h_R1 1 TTSREEVDEAASTLTR 16 1 D6RAU6;D6REP2;D6RAJ6;Q9UKT5-2;Q9UKT5 D6RAU6 FBXO4 F-box only protein 4 1 0 T(0.333)T(0.333)S(0.333)REEVDEAASTLTR 74.726 0.015319 26436000 467.58 311.93 371.99 373.29 447.4 630.4 865.72 5928.9 262.79 595.74 TRUE FALSE FALSE 430.5705496 338.8918393 385.7762766 371.7454249 442.0650472 499.6479339 890.0097732 7736.594317 233.9625945 616.4419207 0.698477075 0.549754694 0.62581123 0.603050202 0.717123597 0.810535295 1.443785284 12.55040265 0.379537125 1 9.267821164 -4.260339414 4.676862966 0.793692503 13.26412658 0.997177367 0.18851643 0.006672738 0.394784899 0.026679174 0.271349919 5.49E-05 4.260339414 12.47043408 up GSTIYTGYPLS(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 1 GSTIYTGYPLSPTK 14 0 H3BLW0;Q5SQL3;J3KP92;Q86Z02-4;Q86Z02-3;Q86Z02 H3BLW0 HIPK1 Homeodomain-interacting protein kinase 1 1 0 GSTIYTGYPLS(0.753)PT(0.247)K 101.3 0.004735 15629000 2595.2 1755.5 2038.9 1924.9 2253.3 3523.9 2944.1 574.47 2380.3 1628.7 TRUE FALSE FALSE 2389.787182 1907.237598 2114.463428 1916.935274 2226.430869 2793.003417 3026.703522 749.6232585 2119.187045 1685.297204 1.418021211 1.131692139 1.254653139 1.137446422 1.321090941 1.65727648 1.795946445 0.444801817 1.257455979 1 10.71878732 -5.605842348 6.38274462 1.198037799 1.371252151 0.008945478 0.349728046 0.554696318 34.37629135 0.049856714 0.100489346 2.48E-06 5.605842348 0.173214352 GSTIYTGYPLSPT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 GSTIYTGYPLSPTK 14 0 H3BLW0;Q5SQL3;J3KP92;Q86Z02-4;Q86Z02-3;Q86Z02 H3BLW0 HIPK1 Homeodomain-interacting protein kinase 1 1 0 GSTIYTGYPLS(0.222)PT(0.777)K 122.64 0.0080178 0 1718.8 1170.1 1162.7 1646.3 1391.5 2345.1 1779.5 418.93 1476.7 1195.8 TRUE FALSE FALSE 1582.755166 1271.23823 1205.790685 1639.488047 1374.907271 1858.699825 1829.427981 546.6598285 1314.709705 1237.353961 1.279145027 1.027384459 0.974491312 1.32499519 1.111167309 1.502156928 1.478500121 0.441797453 1.062517069 1 10.27304255 -6.25358922 24.31996471 1.11494596 1.203759721 0.012607683 0.289602886 1729.127443 5356867.229 0.042620409 0.069750835 5.58E-07 6.25358922 0.08881376 GSTPY(ph)SQDSAYSSSTTSTSFKPR ddPTM_HeLa_Curcumin_4h_R1 1 GSTPYSQDSAYSSSTTSTSFKPR 23 1 O15047 O15047 SETD1A Histone-lysine N-methyltransferase SETD1A 1 0 GS(0.042)T(0.042)PY(0.695)S(0.166)QDS(0.051)AY(0.003)S(0.001)SSTTSTSFKPR 50.055 0.0068872 0 609.65 404.7 705.45 584.37 750.59 837.52 659.23 813.86 677.05 707.84 TRUE FALSE FALSE 561.3955592 439.6804647 731.5945976 581.9520318 741.6397045 663.8089112 677.7262196 1062.002167 602.7793089 732.4373873 0.766475837 0.60029768 0.998849335 0.794541679 1.012563964 0.906301238 0.925302601 1.44995625 0.822977253 1 9.516561625 -4.251249157 3.653546827 0.878132775 1.519685697 0.672869231 0.121678332 0.148505499 3.55199113 0.018536828 0.261448838 5.61E-05 4.251249157 0.641552921 GSTSSSPYVAASHT(ph)PPINGSDSILGTR ddPTM_HeLa_Curcumin_4h_R1 3 GSTSSSPYVAASHTPPINGSDSILGTR 27 0 Q99081;Q99081-3;B4DGI9;F5GY10;Q99081-4;Q99081-2 Q99081 TCF12 Transcription factor 12 1 0 GSTSSSPYVAAS(0.005)HT(0.995)PPINGSDSILGTR;GSTSSSPYVAAS(0.162)HT(0.837)PPINGSDSILGTR;GSTSSSPYVAAS(0.041)HT(0.958)PPINGSDSILGTR ;; 89.239 1.27E-05 21722400 3324.4 2533.01 3101.23 3141.64 3117.12 4595.6 3749.33 3624.57 4244.19 2856.3 TRUE FALSE FALSE 3061.270232 2751.952098 3216.164312 3128.640726 3079.95038 3642.420757 3854.526109 4729.684708 3778.612975 2955.556212 1.035767893 0.931111405 1.088175653 1.058562416 1.042088243 1.232397727 1.304162679 1.600268906 1.27847779 1 11.52921394 -3.553234505 0.657267261 1.01159246 2.744107907 0.749982016 0.094421229 0.936556441 0.144861152 0.006852157 1.511063268 0.000279747 3.553234505 1.732515446 GSVFLESDS(ph)SPPSSSDAGLR ddPTM_HeLa_Curcumin_4h_R1 1 GSVFLESDSSPPSSSDAGLR 20 0 Q8TBP0 Q8TBP0 TBC1D16 TBC1 domain family member 16 1 0 GSVFLES(0.008)DS(0.495)S(0.495)PPS(0.002)SSDAGLR 127.49 7.00E-05 9443500 2329.3 2061.1 1660.6 1983.1 2292 2636 1812.2 1412.3 2010.8 1632.9 TRUE FALSE FALSE 2144.933447 2239.2523 1722.143297 1974.894458 2264.669397 2089.263886 1863.045455 1842.903769 1790.220271 1689.643153 1.269459437 1.325281196 1.019234916 1.168823401 1.340324075 1.236511912 1.102626582 1.090705907 1.059525656 1 10.72250287 -9.415768021 1.146520128 1.000123807 1.201316227 0.295902364 0.09975674 0.442038063 1.040382095 0.070315651 0.017824747 3.84E-10 9.415768021 0.201192421 GSVGAVPSGT(ph)SPGGVATTAAAGSR ddPTM_HeLa_Curcumin_4h_R1 1 GSVGAVPSGTSPGGVATTAAAGSR 24 0 Q6ZNB6-2;Q6ZNB6 Q6ZNB6-2 NFXL1 NF-X1-type zinc finger protein NFXL1 1 0 GSVGAVPS(0.001)GT(0.97)S(0.029)PGGVATTAAAGSR 137.87 1.70E-06 0 993.33 505.93 1067.6 1192.6 1092.8 1701.5 828.17 532.62 1896.2 780.69 TRUE FALSE FALSE 914.7068823 549.6603348 1107.166195 1187.665337 1079.769074 1348.58972 851.4062213 695.0133861 1688.191604 807.8189194 1.132316736 0.680425181 1.370562348 1.470212332 1.336647419 1.669420817 1.053956773 0.860357896 2.089814392 1 9.657888125 GSVLPNSDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 GSVLPNSDKK 10 1 H0YF61;P22307-6;P22307-2;P22307-4;P22307-7;P22307-8;P22307 H0YF61 SCP2 Non-specific lipid-transfer protein 0 1 ; GSVLPNSDK(1)K;GSVLPNSDK(1)K 146.11 4.18E-06 8049400 8622.3 7872 7386.6 6859.7 10076.8 12285.8 10031.3 8934.8 11269.5 7260.5 FALSE TRUE FALSE 7939.835857 8552.420603 7660.353894 6831.316379 9956.640741 9737.58659 10312.75128 11658.97939 10033.26404 7512.801835 1.056840847 1.138379634 1.019640084 0.909290106 1.325289946 1.296132496 1.372690443 1.551881661 1.335488978 1 12.87513533 -5.223375959 1.109643762 1.028656139 1.500066239 0.550954146 0.13033046 0.187630278 0.393009568 0.013390345 0.068555147 5.98E-06 5.223375959 0.471410101 GSVPLSS(ph)SPPATHFPDETEITNPVPK ddPTM_HeLa_Curcumin_4h_R1 1 GSVPLSSSPPATHFPDETEITNPVPK 26 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 GS(0.002)VPLS(0.083)S(0.306)S(0.306)PPAT(0.263)HFPDET(0.034)EIT(0.007)NPVPK 59.614 0.0020853 13032000 933.25 631.59 1046.1 1148.8 1064.9 1115.9 1165.2 554 892.17 783.77 TRUE FALSE FALSE 859.3822777 686.1818253 1084.869386 1144.04657 1052.201763 884.4497612 1197.892376 722.9120497 794.3011831 811.0059492 1.059649783 0.846087289 1.337683635 1.410651267 1.297403261 1.090558907 1.477045116 0.891377 0.979402412 1 9.663568687 -6.747456383 24.99968311 1.01529894 1.263173477 0.394586532 0.165639656 184.5132806 329883.6112 0.023790302 0.033548767 1.79E-07 6.747456383 0.247874537 GSVPLSSSPPAT(ph)HFPDETEITNPVPK ddPTM_HeLa_Curcumin_4h_R1 2 GSVPLSSSPPATHFPDETEITNPVPK 26 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 GSVPLS(0.001)S(0.002)S(0.012)PPAT(0.474)HFPDET(0.474)EIT(0.036)NPVPK;GS(0.002)VPLS(0.042)S(0.217)S(0.237)PPAT(0.471)HFPDET(0.014)EIT(0.017)NPVPK ; 71.634 0.00047613 683370000 4981.5 3128.5 5061.7 5918.5 5473 6084.4 5228.7 2569.2 5252.6 3708.3 TRUE FALSE FALSE 4587.209019 3398.9136 5249.291055 5894.010815 5407.73805 4822.426855 5375.40325 3352.537253 4676.402921 3837.163149 1.19546885 0.885788138 1.368013517 1.536033415 1.409306261 1.256768781 1.400879515 0.873702035 1.218713602 1 11.90582439 -6.736683578 24.99766545 1.079395064 1.324413631 0.270935687 0.185505946 216.63641 218752.4297 0.028435766 0.040204248 1.83E-07 6.736683578 0.245018567 S(ph)KSPVGNPQLIQFSR ddPTM_HeLa_Curcumin_4h_R1 2 SKSPVGNPQLIQFSR 15 1 G8JLP4;Q9Y4F3-3;Q9Y4F3-4;Q9Y4F3-5;Q9Y4F3 G8JLP4 KIAA0430 Meiosis arrest female protein 1 1 0 S(0.988)KS(0.012)PVGNPQLIQFSR;S(0.99)KS(0.01)PVGNPQLIQFSR ; 121.92 0.00051524 83879000 3172.8 2879.81 2477.19 2732.9 2291.59 2916.6 1525.14 929.91 3250.6 2685.8 TRUE FALSE FALSE 2921.669532 3128.727944 2568.996841 2721.591984 2264.264286 2311.664283 1567.931324 1213.435278 2894.017313 2779.13135 1.051288753 1.125793476 0.924388421 0.979295917 0.814738132 0.83179382 0.564180359 0.436623939 1.041338803 1 11.44041831 -4.508117753 0.685100444 1.030516865 0.157730043 0.9280431 0.056576033 0.392339879 0.155292983 0.009648011 0.247688092 3.10E-05 4.508117753 -0.872786822 down NSGSDGSPS(ph)PLLAR ddPTM_HeLa_Curcumin_4h_R1 2 NSGSDGSPSPLLAR 14 0 H7C1V4;Q9HCH0-2;Q9HCH0 H7C1V4 NCKAP5L Nck-associated protein 5-like 1 0 NSGSDGS(0.005)PS(0.995)PLLAR;NSGSDGS(0.015)PS(0.985)PLLAR ; 133.9 0.00096451 127306000 6581.5 5809.5 5558.3 6298.9 6237.6 5494.6 3241.83 734.95 7202.5 5572.3 TRUE FALSE FALSE 6060.56733 6311.647293 5764.295488 6272.836821 6163.220694 4354.958023 3332.787025 959.0328717 6412.40377 5765.93701 1.051098428 1.094643816 0.999715307 1.087912825 1.068901842 0.7552906 0.578013083 0.166327324 1.112118249 1 12.49333936 -4.507803998 1.242039219 1.03689773 7.68E-14 0.961523026 0.057244006 0.120222391 0.210146185 0.008031187 0.14137093 3.11E-05 4.507803998 -1.03689773 down VRTAS(ph)EGDGGAAAGAAAAGAR ddPTM_HeLa_Curcumin_4h_R1 2 VRTASEGDGGAAAGAAAAGAR 21 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 VRT(0.074)AS(0.926)EGDGGAAAGAAAAGAR;VRT(0.036)AS(0.964)EGDGGAAAGAAAAGAR ; 97.94 0.00010145 33697000 4092.6 2928.7 2747.6 3737.9 2310.8 4126.9 1936.97 555.89 5049.1 3690 TRUE FALSE FALSE 3768.666392 3181.843778 2849.428473 3722.43356 2283.245219 3270.93442 1991.316165 725.378302 4495.226362 3818.227225 0.987019936 0.833330127 0.746270011 0.974911481 0.597985684 0.856663113 0.521528984 0.189977772 1.177307189 1 11.89868725 -4.505252361 0.51733523 0.985133716 2.51E-25 0.741213765 0.138785669 1.142527995 0.240105256 0.024939358 0.646158467 3.12E-05 4.505252361 -0.985133716 down STT(ph)PTSSPFR ddPTM_HeLa_Curcumin_4h_R1 1 STTPTSSPFR 10 0 E7EPN9;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-2;A0A2R8Y7F4;A0A2R8YET2;H7C5N8;A0A2R8Y424 E7EPN9 PRRC2C Protein PRRC2C 1 0 S(0.117)T(0.071)T(0.786)PT(0.007)S(0.016)S(0.004)PFR 114.89 0.015944 334660000 12136 8600 10415 9905.4 10169 9967.9 5315.3 1550.1 11262 8798 TRUE FALSE FALSE 11175.42279 9343.345679 10800.98906 9864.414079 10047.74132 7900.445179 5464.433013 2022.718354 10026.58678 9103.729845 1.227565293 1.026320622 1.186435587 1.083557426 1.103695023 0.867825091 0.600241122 0.222185674 1.1013713 1 13.15224203 -4.504437221 1.219059712 1.110865809 0.025923219 0.94974946 0.065883046 0.198198562 0.328753648 0.013336116 0.241084763 3.13E-05 4.504437221 -1.084942589 down GSYGS(ph)DAEEEEYR ddPTM_HeLa_Curcumin_4h_R1 2 GSYGSDAEEEEYR 13 0 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 GS(0.001)YGS(0.999)DAEEEEYR;GSYGS(1)DAEEEEYR ; 209.11 2.85E-09 272590000 4093.6 2975.5 3300.7 3402 3909.9 3835 3402.9 3442.3 3087 3266.2 TRUE FALSE FALSE 3769.58724 3232.688961 3423.026846 3387.923425 3863.276996 3039.577771 3498.376216 4491.841424 2748.363823 3379.700207 1.115361425 0.956501691 1.012819669 1.002433121 1.143082747 0.899363134 1.03511436 1.32906505 0.813197519 1 11.72267956 -4.261163264 23.66094002 1.037310831 1.329065217 0.467958542 0.09812199 5.580406858 477634.3483 0.009820117 0.0768111 5.48E-05 4.261163264 0.291754386 GSYGS(ph)DAEEEEYRQQLSEHSK ddPTM_HeLa_Curcumin_4h_R1 2 GSYGSDAEEEEYRQQLSEHSK 21 1 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 GS(0.003)YGS(0.997)DAEEEEYRQQLSEHSK;GS(0.003)YGS(0.996)DAEEEEYRQQLSEHSK ; 113.89 8.21E-06 107800000 3967.3 2948.4 2573.09 2625.3 4666.5 7851 4047.1 2755.8 4572.7 2688.8 TRUE FALSE FALSE 3653.284019 3203.246558 2668.450979 2614.437204 4610.855035 6222.614101 4160.650734 3596.030734 4071.08625 2782.2356 1.313075003 1.151321102 0.959103168 0.939689365 1.657248234 2.236551822 1.495434367 1.292496845 1.463242815 1 11.44202888 -5.722996938 9.679646908 1.122894737 1.699475712 0.482410245 0.269394622 0.230162111 55.31156696 0.038203369 0.076193938 1.89E-06 5.722996938 0.576580975 GSYSLS(ph)VR ddPTM_HeLa_Curcumin_4h_R1 1 GSYSLSVR 8 0 H0Y3C5;J3KPD6;Q9H6Q3-4;Q9H6Q3-2;Q9H6Q3-3;Q9H6Q3;P08631-3;P08631-2;P08631-4;P08631 H0Y3C5 HCK;SLA2 Non-specific protein-tyrosine kinase;Src-like-adapter 2;Tyrosine-protein kinase HCK 1 0 GSY(0.001)S(0.001)LS(0.999)VR 71.342 0.019985 23985000 7353 9535 7173.6 5322 5890.9 7718.8 5559.7 5715.6 6055.9 7440.6 TRUE FALSE FALSE 6771.002291 10359.16291 7439.459927 5299.978974 5820.654865 6117.833871 5715.690219 7458.260129 5391.582921 7699.160296 0.879446853 1.345492562 0.966269001 0.688384028 0.756011648 0.794610534 0.742378389 0.968710852 0.700281942 1 12.91048539 -6.329386411 8.697445465 0.979990889 0.785867072 0.248184786 0.163792342 0.36969476 44.83011813 0.022165487 0.033894822 4.68E-07 6.329386411 -0.194123817 GT(ph)FSDQELDAQSLDDEDDNMHHAVYPAVNR ddPTM_HeLa_Curcumin_4h_R1 1 GTFSDQELDAQSLDDEDDNMHHAVYPAVNR 30 0 Q9P270;D6RIF6 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 0 GT(0.547)FS(0.452)DQELDAQS(0.001)LDDEDDNMHHAVYPAVNR 85.407 1.81E-06 6891100 886.74 671.84 875.5 1061.9 1164.1 1541.2 1517.9 1106.7 1029.9 862.58 TRUE FALSE FALSE 816.5535933 729.9108559 907.9468002 1057.506139 1150.218868 1221.537747 1560.488189 1444.127735 916.9225467 892.5545908 0.914850029 0.817777269 1.017245118 1.184808358 1.288681812 1.368586033 1.748339211 1.617971327 1.027301362 1 9.8017966 -5.371954645 0.918399396 0.947526316 1.725721171 0.910459414 0.086855043 0.138955032 0.196284885 0.014396807 0.073311739 4.25E-06 5.371954645 0.778194854 GT(ph)PPLTPSDSPQTR ddPTM_HeLa_Curcumin_4h_R1 2 GTPPLTPSDSPQTR 14 0 Q6NZY4;Q6NZY4-2 Q6NZY4 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 0 GT(1)PPLTPSDSPQTR;GT(1)PPLTPSDSPQTR ; 130.19 0.0031483 35827000 896.95 656.06 837.96 768.31 861.44 981.29 607.4 1659.8 750.58 646.81 TRUE FALSE FALSE 825.955461 712.7669031 869.0155347 765.1309368 851.1678906 777.7593926 624.4420093 2165.865379 668.2432519 669.2865994 1.234083369 1.064965149 1.29842064 1.14320373 1.271753971 1.162072262 0.932996432 3.236080599 0.998441105 1 9.386480318 -4.258187734 24.99996824 1.129569204 3.236081378 0.966872173 0.11734154 39.13640557 300882.1875 0.016882638 0.161649856 5.52E-05 4.258187734 2.106512174 GT(ph)PSQS(ph)PVVGR ddPTM_HeLa_Curcumin_4h_R1 1 GTPSQSPVVGR 11 0 C9J2I0;B8ZZY2;P52594-2;P52594-3;P52594;P52594-4 C9J2I0 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 2 0 GT(1)PS(0.171)QS(0.829)PVVGR 122.1 0.017677 32423000 6514.2 5261.9 6564.5 5808.8 7780.6 6198.3 5838.8 1296 5289.2 5153 TRUE FALSE FALSE 5998.594196 5716.715189 6807.786145 5784.764725 7687.821427 4912.702711 6002.621014 1691.144434 4708.987993 5332.066366 1.125003663 1.072138791 1.276763205 1.084901111 1.441809028 0.921350631 1.125758871 0.317164926 0.883145045 1 12.38047902 -4.260148086 24.8874589 1.0969199 0.317164658 0.698857298 0.154786563 39.81464377 767265.8668 0.018945344 0.158063939 5.49E-05 4.260148086 -0.779755242 GT(ph)SPRPPEGGLGYSQLGDDDLK ddPTM_HeLa_Curcumin_4h_R1 1 GTSPRPPEGGLGYSQLGDDDLK 22 1 Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;P21127-5;P21127-10;Q9UQ88-5;Q9UQ88-10;Q9UQ88-8;P21127-12;P21127-4;A0A0D9SEI3;A0A0D9SER5;A0A0D9SEN2;P21127-6;P21127-9;P21127-8;P21127-3;P21127-2;P21127 Q5QPR4;A0A0D9SEI3 CDK11A;CDK11B Cyclin-dependent kinase 11A;Cyclin-dependent kinase 11B 1 0 GT(0.534)S(0.464)PRPPEGGLGYS(0.002)QLGDDDLK 64.502 0.004045 32302000 3048.5 2580.2 3306.9 3046 3720.7 3450.5 2473.8 1621.2 2680 2284.7 TRUE FALSE FALSE 2807.208008 2803.220991 3429.456623 3033.396459 3676.333083 2734.827405 2543.20817 2115.496417 2386.010705 2364.093155 1.187435445 1.185748956 1.450643608 1.283112069 1.555071159 1.156818799 1.075764787 0.894844779 1.009271018 1 11.20707117 -8.5440522 0.823790559 1.015829957 1.237522049 0.198531001 0.174265685 0.712306304 0.991273285 0.080012302 0.039529751 2.86E-09 8.5440522 0.221692091 GTDDS(ph)PKDSQEDLQER ddPTM_HeLa_Curcumin_4h_R1 4 GTDDSPKDSQEDLQER 16 1 Q969E4;Q5H9L2;Q6IPX3-2;Q6IPX3 Q969E4 TCEAL3;TCEAL5;TCEAL6 Transcription elongation factor A protein-like 3;Transcription elongation factor A protein-like 5;Transcription elongation factor A protein-like 6 1 0 GT(0.001)DDS(0.986)PKDS(0.012)QEDLQER;GT(0.008)DDS(0.981)PKDS(0.01)QEDLQER;GT(0.005)DDS(0.866)PKDS(0.129)QEDLQER;GT(0.006)DDS(0.759)PKDS(0.235)QEDLQER ;;; 119.96 0.0089931 167647000 12718 10674.9 10778.8 12068.1 10716 12926.7 12427.6 13012.9 14387.8 12113.5 TRUE FALSE FALSE 11711.35688 11597.59079 11178.27181 12018.1654 10588.2187 10245.55671 12776.28501 16980.47331 12809.49434 12534.44322 0.934334032 0.925257754 0.891804415 0.958811268 0.844729878 0.817392247 1.019294179 1.354705032 1.021943624 1 13.61361029 -4.291874211 3.636912712 0.941442294 1.388439928 0.809507165 0.06204038 0.083616808 1.998714962 0.00915666 0.095901388 5.11E-05 4.291874211 0.446997634 GTDTQTPAVLS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 GTDTQTPAVLSPSK 14 0 P46087;P46087-4;P46087-2 P46087;P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 0 GTDTQTPAVLS(0.921)PS(0.079)K;GTDTQTPAVLS(0.999)PSK ; 226.06 2.83E-20 483780000 10490.6 9772.9 11559.9 11662.8 12978.3 13118.6 12124.2 6194.2 9552 8101.4 TRUE FALSE FALSE 9660.25794 10617.62593 11988.32006 11614.54242 12823.54225 10397.65448 12464.37242 8082.783065 8504.169498 8382.923047 1.152373449 1.266578003 1.430088287 1.385500303 1.529722052 1.24033758 1.486876636 0.964196262 1.014463505 1 13.03323767 -7.511812317 1.179442275 1.045258155 1.352366302 0.417963645 0.151552688 0.273189667 0.762724292 0.031181354 0.03299333 3.08E-08 7.511812317 0.307108147 GTDTQTPAVLS(ph)PSKTQATLKPK ddPTM_HeLa_Curcumin_4h_R1 2 GTDTQTPAVLSPSKTQATLKPK 22 2 P46087;P46087-4;P46087-2 P46087;P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 0 GTDTQT(0.003)PAVLS(0.751)PS(0.183)KT(0.048)QAT(0.015)LKPK;GTDT(0.001)QT(0.001)PAVLS(0.494)PS(0.494)KT(0.01)QAT(0.001)LKPK ; 73.722 0.0012882 560140000 6353.7 5437.7 5545.7 5880.6 5536.6 7729.5 6014.3 3616.1 7033.7 5914.7 TRUE FALSE FALSE 5850.797941 5907.710558 5751.22852 5856.267635 5470.579661 6126.314571 6183.045071 4718.632244 6262.120707 6120.235385 0.955975967 0.965275057 0.93970708 0.956869674 0.893851187 1.000993293 1.010262626 0.770988687 1.023182985 1 12.57937142 GTDVNVFNTILTTR ddPTM_HeLa_Curcumin_4h_R1 1 GTDVNVFNTILTTR 14 0 P04083 P04083 ANXA1 Annexin A1 0 0 156.52 0.0007087 791210 579.17 546.02 889.55 725.21 635.5 1222.1 933.17 668.29 863.2 585.81 FALSE FALSE TRUE 533.3280834 593.2155358 922.5175055 722.2092732 627.9220776 968.6226841 959.3522387 872.0485446 768.5091196 606.1668539 0.879837094 0.978634071 1.521887084 1.191436431 1.035889827 1.597947294 1.582653741 1.438627894 1.267817788 1 9.243571155 -5.9597844 0.594674629 0.936591621 1.570257717 0.361426963 0.205911993 0.502756067 0.314491266 0.041917689 0.153618047 1.10E-06 5.9597844 0.633666096 GTEAPAVVT(ph)EEEDDDEETAPPVIAPRPDHTK ddPTM_HeLa_Curcumin_4h_R1 2 GTEAPAVVTEEEDDDEETAPPVIAPRPDHTK 31 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 0 GTEAPAVVT(1)EEEDDDEETAPPVIAPRPDHTK;GTEAPAVVT(1)EEEDDDEETAPPVIAPRPDHTK ; 110.06 2.61E-11 181766000 9283 7453.1 8400.2 8009.4 8413.5 9724.6 6502.3 4194.9 9420 7797.7 TRUE FALSE FALSE 8548.240755 8097.312754 8711.518802 7976.259225 8313.174508 7707.608341 6684.737038 5473.905699 8386.649568 8068.669495 1.059436226 1.003549936 1.079672281 0.988547025 1.030303015 0.955251463 0.828480711 0.678414911 1.039409233 1 12.97811508 -4.47206993 1.282667263 1.029209432 0.595483184 0.949520235 0.026199808 0.157206485 0.286672363 0.004253925 0.080376752 3.37E-05 4.47206993 -0.433726248 GTEDITSPHGIPLDLLDR ddPTM_HeLa_Curcumin_4h_R1 2 GTEDITSPHGIPLDLLDR 18 0 Q9Y265;Q9Y265-2;E7ETR0;H7C4G5;J3QLR1 Q9Y265 RUVBL1 RuvB-like 1 0 0 ; ; 211.49 5.43E-13 7849200 4224.1 4141.3 3520.3 3514.7 4585.9 7721.8 4846.6 4113.4 5301.4 3643.8 FALSE FALSE TRUE 3889.758028 4499.255519 3650.765415 3500.157103 4531.216138 6120.211637 4982.582552 5367.556724 4719.849683 3770.421779 1.031650636 1.193302973 0.968264462 0.928319776 1.201779643 1.623216711 1.321492089 1.423595831 1.251809469 1 11.8805102 -5.502105326 5.252306477 1.021769111 1.441270112 0.676956944 0.119510675 0.054978251 4.433340894 0.013039133 0.028472473 3.15E-06 5.502105326 0.419501001 GTEFVVFS(ph)IDGS(ph)FAASVS(ph)IMGSDPK ddPTM_HeLa_Curcumin_4h_R1 1 GTEFVVFSIDGSFAASVSIMGSDPK 25 0 Q9BZ72-3;Q9BZ72-2;Q9BZ72 Q9BZ72-3 PITPNM2 Membrane-associated phosphatidylinositol transfer protein 2 3 0 GT(0.131)EFVVFS(0.909)IDGS(0.879)FAAS(0.266)VS(0.805)IMGS(0.01)DPK 43.841 0.015676 13525000 3449.5 2734.2 3007.4 2936.2 2492.9 3630.1 2767.7 2585.4 3656.4 2963 TRUE FALSE FALSE 3176.468435 2970.532065 3118.85689 2924.050782 2463.173796 2877.17634 2845.354213 3373.676558 3255.302068 3065.964029 1.036042303 0.968873749 1.017251624 0.953713336 0.80339292 0.938424689 0.92804553 1.100364038 1.061754814 1 11.58212506 -6.192806998 4.957821886 1.013109618 0.934545509 0.201171567 0.070673696 0.252556114 12.08637477 0.010253933 0.017135916 6.41E-07 6.192806998 -0.078564109 GTENGVNGTLTSNVADS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 GTENGVNGTLTSNVADSPR 19 0 G3XAN4;Q15629-2;Q15629 G3XAN4 TRAM1 Translocating chain-associated membrane protein 1 1 0 GTENGVNGTLTSNVADS(1)PR;GTENGVNGTLTSNVADS(1)PR ; 139.43 0.00013851 15250000 2629.84 2519.78 2416.52 3761.3 2667.26 4578.2 1660.51 952.2 4581.7 3340.1 TRUE FALSE FALSE 2421.685389 2737.578555 2506.078357 3745.736737 2635.454667 3628.629713 1707.099442 1242.521397 4079.098973 3456.168226 0.700685045 0.792084869 0.725103118 1.083783107 0.762536571 1.049899622 0.493928342 0.359508367 1.180237392 1 11.75495773 -4.626248093 5.705189411 0.860491504 0.392478857 0.574602304 0.163711323 0.096616669 4.436186641 0.020200202 0.078877401 2.36E-05 4.626248093 -0.468012647 GTENTFPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 GTENTFPSPK 10 0 J3QSD2;J3QRZ1;A6NIZ0;Q9GZM8-3;Q9GZM8;Q9GZM8-2 J3QSD2 NDEL1 Nuclear distribution protein nudE-like 1 1 0 GT(0.007)ENT(0.044)FPS(0.95)PK 97.957 0.013932 23811000 6003.5 5497.6 5411 5111 5577.6 6573.6 5522.7 3503.3 6055.2 5261.2 TRUE FALSE FALSE 5528.31664 5972.788047 5611.53642 5089.852036 5511.090763 5210.16126 5677.652098 4571.440043 5390.959709 5444.026308 1.015483087 1.097126962 1.030769526 0.934942586 1.012318907 0.957041896 1.042914155 0.839716743 0.990252325 1 12.41045832 -6.273133367 24.70918308 1.017261637 0.96517099 0.257013484 0.05707635 845.2284299 1785949.501 0.008204808 0.012604429 5.33E-07 6.273133367 -0.052090647 GTEPS(ph)PGGT(ph)PQPSRPVS(ph)PAGPPEGVPEEAQPPR ddPTM_HeLa_Curcumin_4h_R1 1 GTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPR 33 1 I3L1Q2;Q8WUZ0;Q8WUZ0-2 I3L1Q2 BCL7C B-cell CLL/lymphoma 7 protein family member C 3 0 GT(0.399)EPS(0.653)PGGT(0.843)PQPS(0.424)RPVS(0.681)PAGPPEGVPEEAQPPR 47.983 0.011999 6818800 737.78 705.46 593.33 615.94 417.18 755.44 633.85 891.35 698.55 733.92 TRUE FALSE FALSE 679.3839345 766.4368189 615.3193317 613.3914035 412.205401 598.7532284 651.6341251 1163.118512 621.9208127 759.4236654 0.89460464 1.009234837 0.810245137 0.807706464 0.542787142 0.78843109 0.858064022 1.531580546 0.818937888 1 9.568761147 -4.259590619 24.83063325 0.891844899 1.531580783 0.69558075 0.133497439 76.48158592 1027129.831 0.02095267 0.181010824 5.50E-05 4.259590619 0.639735884 GTEPSPGGT(ph)PQPSRPVS(ph)PAGPPEGVPEEAQPPR ddPTM_HeLa_Curcumin_4h_R1 1 GTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPR 33 1 I3L1Q2;Q8WUZ0;Q8WUZ0-2 I3L1Q2 BCL7C B-cell CLL/lymphoma 7 protein family member C 2 0 GT(0.021)EPS(0.273)PGGT(0.697)PQPS(0.145)RPVS(0.864)PAGPPEGVPEEAQPPR 55.344 0.0019555 46836000 1345.2 1234.3 1121.6 1301.2 1361.8 1267.4 1059.1 1034.3 1344.1 1068.4 TRUE FALSE FALSE 1238.726001 1340.987392 1163.167483 1295.815979 1345.561424 1004.526953 1088.815496 1349.653309 1196.655593 1105.52682 1.120484802 1.212984947 1.052138638 1.172125321 1.217122371 0.908640962 0.984883836 1.220823669 1.082430178 1 10.11051831 -3.36328014 14.05753192 1.078480247 1.09003255 0 0.106105083 0 0 0.01429581 0 0.000433231 3.36328014 0.011552303 GTEPSPGGTPQPS(ph)RPVS(ph)PAGPPEGVPEEAQPPR ddPTM_HeLa_Curcumin_4h_R1 1 GTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPR 33 1 I3L1Q2;Q8WUZ0;Q8WUZ0-2 I3L1Q2 BCL7C B-cell CLL/lymphoma 7 protein family member C 2 0 GT(0.136)EPS(0.228)PGGT(0.371)PQPS(0.548)RPVS(0.718)PAGPPEGVPEEAQPPR 50.704 0.0048205 0 553.6 682.89 706.62 603.34 662.82 761.04 499.81 423.12 745.34 643.04 TRUE FALSE FALSE 509.7819758 741.9159687 732.8079588 600.8435389 654.9163044 603.1917253 513.8333234 552.1273402 663.5780667 665.3855921 0.766145197 1.115016582 1.101328264 0.903000525 0.984265833 0.906529586 0.772233919 0.829785536 0.997283492 1 9.378046817 -4.844269437 5.621611059 0.927833857 0.801656198 0.22762771 0.103407969 0.291187769 14.85487904 0.017720303 0.055583071 1.43E-05 4.844269437 -0.126177659 GTEVQVDDIK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 GTEVQVDDIKR 11 1 Q9Y230;Q9Y230-2 Q9Y230 RUVBL2 RuvB-like 2 0 1 GTEVQVDDIK(1)R 93.561 0.0057443 2465600 736.28 734.45 556.96 669.91 999.1 1063.5 1095.7 818.98 1284.7 662.63 FALSE TRUE FALSE 678.0026611 797.9325854 577.6014276 667.1380899 987.186385 842.9181119 1126.442393 1068.683232 1143.771624 685.6563432 0.988837437 1.163750023 0.842406598 0.972991932 1.439768471 1.22935946 1.642867311 1.558628083 1.668141242 1 9.421341856 -5.340343163 1.148912075 0.993450824 1.596920233 0.262091824 0.249245251 0.180155511 0.425254045 0.018809152 0.080985182 4.57E-06 5.340343163 0.603469409 GTFHDDRDDGVDYWAK ddPTM_HeLa_Curcumin_4h_R1 1 GTFHDDRDDGVDYWAK 16 1 E9PK91;Q9NYF8-3;H0YF63 E9PK91 BCLAF1 Bcl-2-associated transcription factor 1 0 0 141.06 0.00033761 9044300 1892.6 1984.1 1962.6 2095.2 1960.4 2794.8 1998.7 1976.7 2511.6 1935.6 FALSE FALSE TRUE 1742.798713 2155.596763 2035.335682 2086.530618 1937.02351 2215.126976 2054.778143 2579.38673 2236.083764 2002.861956 0.870154185 1.07625828 1.016213662 1.041774552 0.967127817 1.105980854 1.025921001 1.28785048 1.116444275 1 10.96784727 -1 0.45441567 0.951975097 7.869182839 0.351350115 0.08381701 40.31747647 0.431044903 0.015966404 261.6392519 0.1 1 6.917207742 GTGIVSAPVPK ddPTM_HeLa_Curcumin_4h_R1 2 GTGIVSAPVPK 11 0 P15880;H0YEN5;E9PQD7;E9PMM9;I3L404;E9PM36 P15880 RPS2 40S ribosomal protein S2 0 0 ; ; 109.83 0.0046517 5556500 8836.7 6410.9 7807.6 6670 7860.9 9735.1 6486.7 7145.2 8200.6 7811.6 FALSE FALSE TRUE 8137.265871 6965.02963 8096.956524 6642.401307 7767.163902 7715.930523 6668.699344 9323.738588 7301.014697 8083.052519 1.006707039 0.861683085 1.001720143 0.821768916 0.960919638 0.954581268 0.825022395 1.153492269 0.903249692 1 12.98068451 -7.375440614 22.35200033 1.003168941 0.934628072 0 0.096731839 14.77040635 2865.303656 0.013870819 0.015861777 4.21E-08 7.375440614 -0.068540869 GTGQS(ph)DDS(ph)DIWDDTALIK ddPTM_HeLa_Curcumin_4h_R1 1 GTGQSDDSDIWDDTALIK 18 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 2 0 GT(0.007)GQS(0.993)DDS(0.994)DIWDDT(0.006)ALIK 93.348 0.0019937 0 964.93 871.58 865.14 759.09 925.53 1041.7 953.15 748.73 1181.5 884.81 TRUE FALSE FALSE 888.5547723 946.9154915 897.2028495 755.9490867 914.4936592 825.6396776 979.8928237 977.0143303 1051.892406 915.5570816 0.970507236 1.034250633 0.979952935 0.82567117 0.998838497 0.901789407 1.070269504 1.067125524 1.148909693 1 9.838506025 -4.728071372 24.80669637 0.973738418 1.068697762 0.152202684 0.079259679 159.4965799 118571.7821 0.007747629 0.028985058 1.87E-05 4.728071372 0.094959344 GTGQSDDS(ph)DIWDDT(ph)ALIK ddPTM_HeLa_Curcumin_4h_R1 3 GTGQSDDSDIWDDTALIK 18 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 2 0 GTGQSDDS(1)DIWDDT(1)ALIK;GT(0.002)GQS(0.031)DDS(0.992)DIWDDT(0.975)ALIK;GTGQS(0.022)DDS(0.978)DIWDDT(0.999)ALIK ;; 158.45 3.81E-10 11908700 3920.01 3526.33 4215.91 4489.65 3764.83 4686.05 3286.3 2563.46 4189.66 3818.37 TRUE FALSE FALSE 3609.737072 3831.130252 4372.155333 4471.073018 3719.936861 3714.110407 3378.504733 3345.047153 3730.06478 3951.058073 0.91361276 0.969646657 1.106578352 1.131614098 0.94150397 0.940029313 0.855088604 0.846620599 0.944067313 1 11.94802334 -4.892594776 2.164768388 0.982528621 0.843846077 0.422270967 0.067728531 0.30813151 2.786123123 0.011363042 0.050527522 1.28E-05 4.892594776 -0.138682544 GTGQSDDS(ph)DIWDDTALIK ddPTM_HeLa_Curcumin_4h_R1 1 GTGQSDDSDIWDDTALIK 18 0 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 1 0 GTGQS(0.001)DDS(0.78)DIWDDT(0.219)ALIK 202.81 4.74E-12 89281000 3663.6 2758.8 2718.7 2391.9 2927.2 3349.5 2196.9 1144.9 3008.3 2729.8 TRUE FALSE FALSE 3373.622194 2997.258379 2819.457414 2382.002952 2892.295052 2654.775943 2258.539101 1493.97474 2678.297016 2824.660347 1.194346144 1.061103995 0.998158032 0.843288275 1.023944367 0.939856697 0.799579002 0.528904207 0.948183742 1 11.46386168 -3.884124768 0.587625994 1.08110644 1.05E-12 0.712555593 0.091479228 2.016361215 0.348488695 0.018714104 1.631528517 0.00013058 3.884124768 -1.08110644 STS(ph)PTFNK ddPTM_HeLa_Curcumin_4h_R1 4 STSPTFNK 8 0 Q9BX63 Q9BX63 BRIP1 Fanconi anemia group J protein 1 0 S(0.042)T(0.068)S(0.884)PT(0.006)FNK;S(0.061)T(0.061)S(0.873)PT(0.005)FNK;S(0.037)T(0.066)S(0.896)PT(0.001)FNK;S(0.073)T(0.073)S(0.843)PT(0.012)FNK ;;; 128.86 0.0056252 134228000 33628.8 27276.6 29569.4 31559.4 28946.5 30413.6 20775.8 11490.6 35310.6 30339.4 TRUE FALSE FALSE 30967.045 29634.26776 30665.26798 31428.81556 28601.33189 24105.47653 21358.71303 14994.03104 31437.11552 31393.69189 0.986409789 0.943956125 0.976797125 1.001118813 0.911053469 0.767844592 0.68035047 0.477612862 1.001383196 1 14.93818708 -4.499720907 0.830031258 0.992194265 0.298376697 0.978618526 0.024625594 0.165812946 0.103268508 0.004015732 0.0971534 3.16E-05 4.499720907 -0.693817567 down GTHDLWDSR ddPTM_HeLa_Curcumin_4h_R1 1 GTHDLWDSR 9 0 E9PGM4;Q04446 E9PGM4 GBE1 "1,4-alpha-glucan-branching enzyme" 0 0 117.53 0.0054886 5831600 2259.4 1860.1 2105.1 2183.2 2432.6 2604.1 2101 1481.5 2460.9 2107.4 FALSE FALSE TRUE 2080.566106 2020.878756 2183.116858 2174.166497 2403.592834 2063.980306 2159.948405 1933.20253 2190.945427 2180.631993 0.95411152 0.926739937 1.001139516 0.997035036 1.102245973 0.94650556 0.990514866 0.886533141 1.004729562 1 11.0905306 -4.259029328 24.09942506 0.984003602 0.886533086 0.311933717 0.045553628 134.2920728 1342711.295 0.006308194 0.05658068 5.51E-05 4.259029328 -0.097470516 GTHDRDPSEK(ac)PPR ddPTM_HeLa_Curcumin_4h_R1 2 GTHDRDPSEKPPR 13 2 Q969S3 Q969S3 ZNF622 Zinc finger protein 622 0 1 ; GTHDRDPSEK(1)PPR;GTHDRDPSEK(1)PPR 72.29 0.010302 833290 493.33 607.53 583.81 713.63 966.84 1136.3 900.81 907.63 1187.02 344.21 FALSE TRUE FALSE 454.2824099 660.0421861 605.4465122 710.6771881 955.3110645 900.6185713 926.0843042 1184.362209 1056.806876 356.1712719 1.27546056 1.853159528 1.699874639 1.995324284 2.682167653 2.528610931 2.60010949 3.325260352 2.967131151 1 8.476427346 -5.671853864 0.36927213 0.970903741 3.58063995 0.174545888 0.64639753 0.386020006 0.075395906 0.072701309 0.396949856 2.13E-06 5.671853864 2.609736208 GTIQVITQGTSLK ddPTM_HeLa_Curcumin_4h_R1 1 GTIQVITQGTSLK 13 0 A0A286YF22;A0A2C9F2M7;O43175 A0A286YF22 PHGDH D-3-phosphoglycerate dehydrogenase 0 0 158.86 8.32E-05 1357900 1182.6 1078.9 855.26 864.4 988.79 1416.4 924.98 897.39 1138 1174.7 FALSE FALSE TRUE 1088.995962 1172.155309 886.956688 860.8233418 976.999325 1122.622674 950.9324493 1171.00008 1013.164247 1215.520738 0.895908995 0.964323579 0.729692765 0.708193053 0.803770182 0.923573444 0.782325155 0.963373181 0.833522799 1 10.24735879 -7.845204843 0.756937303 0.981133028 0.82633972 0.044717507 0.095972994 0.464247301 0.583475084 0.027634725 0.022278044 1.43E-08 7.845204843 -0.154793308 GTLDEEDEEADS(ph)DTDDIDHR ddPTM_HeLa_Curcumin_4h_R1 4 GTLDEEDEEADSDTDDIDHR 20 0 Q9HCN4-3;Q9HCN4-2;Q9HCN4-4;Q9HCN4;Q9HCN4-5 Q9HCN4-3 GPN1 GPN-loop GTPase 1 1 0 GTLDEEDEEADS(0.885)DT(0.115)DDIDHR;GTLDEEDEEADS(0.684)DT(0.316)DDIDHR;GTLDEEDEEADS(0.99)DT(0.01)DDIDHR;GTLDEEDEEADS(0.978)DT(0.022)DDIDHR ;;; 138 3.94E-05 877080000 19827.2 16784.3 19653.8 18226.7 21176.3 21714.5 19660 16585.7 16969.4 16563 TRUE FALSE FALSE 18257.8562 18235.0601 20382.18712 18151.28274 20923.78645 17210.66793 20211.60669 21642.60358 15107.89928 17138.56302 1.065308461 1.063978356 1.189258813 1.059090119 1.220860024 1.004207174 1.179305795 1.262801529 0.881514936 1 14.06495853 -1.000000017 0.106216513 0.931550445 1.744302332 0.512630427 0.078336217 69.92451309 0.523965964 0.429280083 8.345007084 0.099999996 1.000000017 0.812751887 GTLDPVEK ddPTM_HeLa_Curcumin_4h_R1 2 GTLDPVEK 8 0 P11142;E9PKE3;E9PNE6;P11142-2;E9PN89;A8K7Q2 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 ; ; 125.96 0.0020799 72662000 14022.5 11375.5 12946.1 13136 13255.6 14866 11565.3 11427.5 13981.8 12873.9 FALSE FALSE TRUE 12912.60433 12358.74753 13425.89385 13081.64671 13097.53563 11782.62403 11889.79119 14911.69214 12448.03152 13321.26707 0.969322532 0.927745647 1.007854117 0.982012195 0.983204943 0.884497245 0.892542063 1.119389925 0.934448011 1 13.70144369 -8.915347508 0.758239382 1.000198883 0.966057073 0 0.0659163 2.043665205 2.177472626 0.039437826 0.012719083 1.22E-09 8.915347508 -0.034141809 GTLS(ph)DSEIETNSATSTIFGK ddPTM_HeLa_Curcumin_4h_R1 1 GTLSDSEIETNSATSTIFGK 20 0 A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-4;Q8WXG6-7;Q8WXG6-3;Q8WXG6-2;Q8WXG6;F8W8U2 A0A0A0MRB5 MADD MAP kinase-activating death domain protein 1 0 GT(0.176)LS(0.815)DS(0.009)EIETNSATSTIFGK 164.19 2.23E-06 17685000 5726 5085.4 4646.4 5305.7 5083.6 5866.3 3997.2 3147.2 5876.3 4873.5 TRUE FALSE FALSE 5272.781058 5524.959316 4818.599671 5283.746419 5022.98139 4649.563253 4109.350674 4106.766792 5231.684592 5042.853762 1.045594678 1.095601732 0.95553032 1.047769114 0.9960593 0.922010328 0.814885949 0.814373564 1.037445232 1 12.30002467 -5.004633357 1.802785032 1.024505083 0.804118201 0.856732077 0.03476772 0.099524283 0.605917947 0.005144027 0.022626546 9.89E-06 5.004633357 -0.220386881 GTNESLER ddPTM_HeLa_Curcumin_4h_R1 2 GTNESLER 8 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 0 ; ; 143.37 0.00049685 23229000 10721.2 11046.4 10931.2 9205 11772.2 13141.6 10131.4 9484 9074 9047.8 FALSE FALSE TRUE 9872.605707 12001.20159 11336.31989 9166.912149 11631.8242 10415.88402 10415.65982 12375.62794 8078.604902 9362.210377 1.054516541 1.281876941 1.210859341 0.979139731 1.242422861 1.112545393 1.112521445 1.321870311 0.86289504 1 13.19263347 -7.450080787 7.246872633 1.023791796 1.171028984 0.426007986 0.105768324 0.214083157 18.45105321 0.015360884 0.017438171 3.55E-08 7.450080787 0.147237188 GTNSS(ph)DSEELSAGESITK ddPTM_HeLa_Curcumin_4h_R1 2 GTNSSDSEELSAGESITK 18 0 H7C5R6;Q4LE39-2;Q4LE39 H7C5R6 ARID4B AT-rich interactive domain-containing protein 4B 1 0 GTNS(0.027)S(0.972)DS(0.001)EELSAGESITK;GTNS(0.038)S(0.514)DS(0.447)EELSAGESITK ; 327.62 3.33E-132 31822000 5840.7 4637.4 4609.1 4809.6 5209.7 5943.5 3367.2 2804.1 5539.9 4345.4 TRUE FALSE FALSE 5378.402432 5038.236192 4779.917301 4789.69915 5147.57773 4710.751103 3461.67457 3659.057182 4932.18683 4496.402327 1.196156847 1.120503866 1.063053738 1.065229221 1.144821427 1.047671174 0.769876519 0.813774417 1.096918485 1 12.13455541 -4.815317547 4.794343402 1.095196379 0.789872427 0.848139928 0.051017301 0.070914705 3.353638196 0.010488869 0.034709229 1.53E-05 4.815317547 -0.305323952 GTPAGTT(ph)PGASQAPK ddPTM_HeLa_Curcumin_4h_R1 1 GTPAGTTPGASQAPK 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 GTPAGT(0.093)T(0.762)PGAS(0.144)QAPK 138.31 0.0016455 7190600 1980.5 1700.6 1841.3 1951.2 1817.8 2666 2192.3 1431 2473.1 1341.9 TRUE FALSE FALSE 1823.741335 1847.592286 1909.540198 1943.126451 1796.123922 2113.041548 2253.810038 1867.305312 2201.807117 1388.530925 1.313432277 1.330609389 1.375223384 1.399411721 1.293542614 1.521782129 1.623161571 1.344806427 1.585709816 1 10.43934359 -11.30569841 0.145125939 0.211965639 1.602122758 0 0.203302946 10.5941944 0.199460238 2.858914011 0.259917021 4.95E-12 11.30569841 1.390157119 GTPGS(ph)PSGTQEPR ddPTM_HeLa_Curcumin_4h_R1 4 GTPGSPSGTQEPR 13 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 0 GTPGS(0.961)PS(0.039)GTQEPR;GT(0.003)PGS(0.956)PS(0.04)GT(0.001)QEPR;GT(0.002)PGS(0.836)PS(0.123)GT(0.039)QEPR;GT(0.001)PGS(0.943)PS(0.051)GT(0.004)QEPR ;;; 172.85 0.00020477 88408000 5747.6 4795.79 5428.8 6054.7 4977.9 5846.3 5228.5 4547.24 5835.9 5441.2 TRUE FALSE FALSE 5292.671395 5210.316718 5629.996104 6029.647256 4918.541794 4633.711479 5375.197638 5933.672543 5195.716371 5630.281295 0.940036762 0.925409663 0.999949347 1.070931795 0.873587222 0.822998219 0.954694332 1.053885629 0.922816481 1 12.45899129 -5.714698971 24.99985794 0.975727404 0.920942154 0.111126086 0.06891572 207.3569463 110906.9771 0.010099596 0.020199144 1.93E-06 5.714698971 -0.05478525 GTPKPPGPPAQPPGPPNAS(ph)SNPDLRR ddPTM_HeLa_Curcumin_4h_R1 1 GTPKPPGPPAQPPGPPNASSNPDLRR 26 2 Q8N4C8;Q8N4C8-4 Q8N4C8 MINK1 Misshapen-like kinase 1 1 0 GTPKPPGPPAQPPGPPNAS(0.5)S(0.5)NPDLRR 51.232 0.0048096 18216000 1141.6 982.84 998.31 949.91 860.31 1250.2 982.12 748.91 1262.7 878.12 TRUE FALSE FALSE 1051.241155 1067.79231 1035.308247 945.9795241 850.0513651 990.8944273 1009.675644 977.2492114 1124.184969 908.6346046 1.156945982 1.175161396 1.139410982 1.041100041 0.935526075 1.090531246 1.111200959 1.075513971 1.237224472 1 9.82755644 GTPLISPLIK ddPTM_HeLa_Curcumin_4h_R1 2 GTPLISPLIK 10 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 0 ; ; 120.99 2.70E-07 0 1766.6 1455.22 1766.74 1747.47 1650.85 1753.13 1256.59 1134.03 1873.62 1559.31 FALSE FALSE TRUE 1626.771746 1581.002732 1832.216939 1740.239432 1631.164692 1389.511076 1291.846533 1479.790527 1668.088574 1613.495906 1.008227997 0.979861632 1.135557228 1.078552121 1.010950623 0.861180416 0.800650642 0.917133115 1.033835021 1 10.6559742 -5.26027849 5.597121024 1.018621444 0.852545356 0.704533737 0.051318343 0.073918683 8.977747009 0.007604942 0.018549835 5.49E-06 5.26027849 -0.166076088 GTPPLTPSDS(ph)PQTR ddPTM_HeLa_Curcumin_4h_R1 2 GTPPLTPSDSPQTR 14 0 Q6NZY4;Q6NZY4-2 Q6NZY4 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 0 GTPPLTPS(0.014)DS(0.934)PQT(0.051)R;GTPPLT(0.003)PS(0.258)DS(0.627)PQT(0.111)R ; 187.08 2.20E-06 14026000 2857.5 1950.1 2314.7 2625.5 2518.8 3041.8 2211.07 1610.9 2740 2604.26 TRUE FALSE FALSE 2631.32586 2118.657955 2400.484818 2614.636377 2488.764955 2410.896392 2273.106673 2102.055994 2439.428855 2694.757841 0.976460972 0.786214599 0.890797971 0.970267657 0.923557923 0.894661611 0.843529106 0.780053763 0.905249747 1 11.39593992 -1 0.128407698 1.047361048 0.273079135 0.193305925 0.064715893 52.6630368 0.457546013 0.218407009 7.396939216 0.1 1 -0.774281913 GTPSQS(ph)PVVGR ddPTM_HeLa_Curcumin_4h_R1 4 GTPSQSPVVGR 11 0 C9J2I0;B8ZZY2;P52594-2;P52594-3;P52594;P52594-4 C9J2I0 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 1 0 GTPS(0.016)QS(0.984)PVVGR;GTPS(0.002)QS(0.998)PVVGR;GT(0.004)PS(0.385)QS(0.611)PVVGR;GT(0.004)PS(0.149)QS(0.846)PVVGR ;;; 135.04 0.00209 1842051000 13788.9 10819.5 9902.7 10667.5 10657.9 12921.6 9740.4 4947.76 12881.3 10547.9 TRUE FALSE FALSE 12697.49402 11754.68937 10269.70277 10623.36071 10530.8115 10241.5145 10013.68941 6456.309247 11468.25362 10914.43874 1.163366648 1.076985235 0.940928161 0.973330921 0.9648514 0.938345502 0.917471768 0.591538365 1.050741489 1 13.41395032 -3.63903708 0.596173031 1.067518656 3.51E-16 0.779997422 0.066903094 2.632955295 0.378499737 0.015078044 2.289504188 0.000229595 3.63903708 -1.067518656 GTQGATAGAS(ph)SELDASK ddPTM_HeLa_Curcumin_4h_R1 2 GTQGATAGASSELDASK 17 0 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 0 GTQGAT(0.027)AGAS(0.726)S(0.241)ELDAS(0.005)K;GTQGAT(0.2)AGAS(0.4)S(0.4)ELDASK ; 121.51 0.00058114 15691100 4010.71 3707.06 3975.59 4667.9 4298.81 4168.9 3136.59 3470.2 4400 4445.38 TRUE FALSE FALSE 3693.258071 4027.481748 4122.928863 4648.585467 4247.549498 3304.223147 3224.594274 4528.248005 3917.331008 4599.856624 0.802907215 0.875566801 0.89631682 1.010593557 0.923409107 0.718331769 0.701020605 0.984432424 0.851620241 1 12.16737318 -9.455869179 1.138119769 1.001613478 0.856379353 0 0.106242129 0.631867352 1.437909484 0.073811982 0.017480609 3.50E-10 9.455869179 -0.145234125 GTQS(ph)TEGS(ph)PVSK ddPTM_HeLa_Curcumin_4h_R1 2 GTQSTEGSPVSK 12 0 A0A087WXK8;Q9H4H8-2;Q9H4H8 A0A087WXK8 FAM83D Protein FAM83D 2 0 GT(0.26)QS(0.606)T(0.477)EGS(0.625)PVS(0.032)K;GT(0.006)QS(0.498)T(0.495)EGS(0.827)PVS(0.174)K ; 118.52 0.0088707 230500000 12596.4 10543.4 12493.6 11554 11877.7 13646.9 11310.1 5740.9 11815.8 10655.6 TRUE FALSE FALSE 11599.38165 11454.72452 12956.62381 11506.19261 11736.06619 10816.37911 11627.43097 7491.273982 10519.6363 11025.88131 1.052014014 1.038894234 1.175110038 1.043562169 1.064410713 0.980999052 1.054557966 0.679426322 0.954085756 1 13.42860636 -4.259884731 24.95182569 1.038530519 0.6794262 0.787096268 0.056314541 41.36952379 663908.5146 0.007196087 0.06096579 5.50E-05 4.259884731 -0.359104319 GTQSIPNDS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 2 GTQSIPNDSPAR 12 0 Q9NQ92;H9KV77;J3QRX6 Q9NQ92 COPRS Coordinator of PRMT5 and differentiation stimulator 1 0 GTQSIPNDS(1)PAR;GTQSIPNDS(1)PAR ; 186.69 2.67E-05 210820000 8692.4 7443.4 8374.9 8372.4 10334.3 10488.8 7544.5 5116.7 7650.1 6898.2 TRUE FALSE FALSE 8004.387368 8086.774329 8685.281161 8337.757227 10211.07022 8313.304647 7756.178365 6676.758276 6810.90317 7137.911937 1.121390603 1.132932768 1.216781776 1.168094718 1.430540235 1.164668985 1.086617268 0.935393759 0.954187055 1 12.80128639 -8.341269287 0.731412835 1.010714834 1.171274929 0.262462872 0.117550878 0.706142366 0.806252947 0.052735162 0.028578737 4.56E-09 8.341269287 0.160560096 GTQSTEGS(ph)PVSK ddPTM_HeLa_Curcumin_4h_R1 1 GTQSTEGSPVSK 12 0 A0A087WXK8;Q9H4H8-2;Q9H4H8 A0A087WXK8 FAM83D Protein FAM83D 1 0 GTQS(0.004)T(0.002)EGS(0.981)PVS(0.014)K 145.86 0.00082619 22558000 5668 4904 5088.5 4094.6 4277.3 5971.3 3451.2 1870.4 5579.5 4546.4 TRUE FALSE FALSE 5219.371819 5327.879908 5277.084286 4077.65763 4226.295991 4732.78507 3548.031384 2440.67635 4967.442809 4704.387062 1.109469045 1.132534343 1.121736842 0.866777664 0.898373356 1.006036495 0.754196314 0.518808575 1.055917114 1 12.19979105 -3.966553822 0.71658302 1.055477405 3.25E-14 0.81261258 0.079681809 1.343845377 0.364397962 0.01466727 1.260287707 0.000108006 3.966553822 -1.055477405 GTSGS(ph)LADVFANTR ddPTM_HeLa_Curcumin_4h_R1 1 GTSGSLADVFANTR 14 0 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 1 0 GTSGS(1)LADVFANTR 121.99 0.001885 0 1045.1 971.15 868.96 898.22 1285.5 1568.7 1168.7 1385.9 1185.6 1010.7 TRUE FALSE FALSE 962.3792322 1055.091879 901.164422 894.5034036 1270.171252 1243.333937 1201.490577 1808.45453 1055.542646 1045.82175 0.920213442 1.008863966 0.861680704 0.855311533 1.214519828 1.188858367 1.148848336 1.729218703 1.009294984 1 10.03042126 -1 0.657117624 0.956914147 70.36058651 0.832058165 0.099915515 58.85028584 0.343210066 0.016733451 5962.953841 0.1 1 69.40367236 GTSISTK(ac)PPLTK ddPTM_HeLa_Curcumin_4h_R1 2 GTSISTKPPLTK 12 1 C9JW34;C9JGY5;F8WE44;C9JXZ7;C9JTT7;C9J8M3;C9JZI1;P35249-2;P35249 C9JW34 RFC4 Replication factor C subunit 4 0 1 ; GTSISTK(1)PPLTK;GTSISTK(1)PPLTK 213.63 6.06E-22 15403500 20806.8 15952.3 18131 18812.6 19045.5 23743 19514.3 21113.8 21270.8 18699.7 FALSE TRUE FALSE 19159.91982 17331.14573 18802.95081 18734.75845 18818.39485 18818.43416 20061.81874 27551.30042 18937.44646 19349.51318 0.990201647 0.89568898 0.971753172 0.96822893 0.972551334 0.972553365 1.036812583 1.423875638 0.978704026 1 14.24000965 -4.256776999 3.315885848 0.98193998 1.48628698 0.956303792 0.028915446 0.052142481 0.919770237 0.004471598 0.067240404 5.54E-05 4.256776999 0.504347 GTSS(ph)PDYR ddPTM_HeLa_Curcumin_4h_R1 2 GTSSPDYR 8 0 Q66K14;Q66K14-2;G3V133 Q66K14 TBC1D9B TBC1 domain family member 9B 1 0 GT(0.001)S(0.068)S(0.931)PDYR;GT(0.002)S(0.18)S(0.819)PDYR ; 126.24 0.006325 125758000 21853.1 22471.7 22684 20082.4 22072.3 22826.7 15052 13028 19847.6 20810.8 TRUE FALSE FALSE 20123.40408 24414.05362 23524.68899 19999.30435 21809.10224 18092.18511 15474.31861 17000.17723 17670.36794 21533.97375 0.934495616 1.133745861 1.092445327 0.928732643 1.012776485 0.840169368 0.718600236 0.789458435 0.820580917 1 14.39432695 -5.090858863 3.29578284 0.990016613 0.755615165 0.570097202 0.083985745 0.111844866 2.29967486 0.010128929 0.029901429 8.11E-06 5.090858863 -0.234401449 AKLDPEPEKAAESPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 AKLDPEPEKAAESPSPR 17 2 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 AKLDPEPEKAAES(0.05)PS(0.95)PR 93.776 0.0024236 6739200 6473.7 5250.1 5367.7 6327 4545.1 5274.8 3140.9 1698.1 8160.9 6458 TRUE FALSE FALSE 5961.299814 5703.89525 5566.631684 6300.82055 4490.902651 4180.747021 3229.025201 2215.842873 7265.669688 6682.415019 0.892087635 0.853567944 0.833026932 0.942895724 0.672047851 0.625634147 0.48321231 0.331593124 1.087282018 1 12.70615387 -4.498853595 0.484395812 0.957341162 4.27E-19 0.910852437 0.067702405 0.63027761 0.114761349 0.012818917 0.328062922 3.17E-05 4.498853595 -0.957341162 down GTTATSAQANSTPTSVASVVTSAES(ph)PASR ddPTM_HeLa_Curcumin_4h_R1 1 GTTATSAQANSTPTSVASVVTSAESPASR 29 0 Q86YP4-2;Q86YP4;Q86YP4-3 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 0 GTTATSAQANSTPTSVAS(0.001)VVT(0.017)S(0.059)AES(0.762)PAS(0.16)R 102.55 2.07E-09 13770000 3169.7 2973.5 2776.4 2681.7 3086.8 3886.1 3324 1692.9 3580.1 2870.1 TRUE FALSE FALSE 2918.8149 3230.51609 2879.295826 2670.603836 3049.991926 3080.079055 3417.262494 2209.057417 3187.371987 2969.835761 0.982820309 1.087776008 0.969513488 0.899242938 1.0269901 1.037121007 1.150657063 0.743831509 1.073248571 1 11.53616743 GTTATSAQANSTPTSVASVVTSAESPAS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 GTTATSAQANSTPTSVASVVTSAESPASR 29 0 Q86YP4-2;Q86YP4;Q86YP4-3 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 0 GTTATSAQANSTPTSVASVVT(0.005)S(0.013)AES(0.196)PAS(0.786)R 115.3 5.31E-13 15058000 2957.3 2152.3 2309.9 2617.5 2550.1 3305.7 2564.7 1294.8 2922.5 2877.1 TRUE FALSE FALSE 2723.226584 2338.335222 2395.506926 2606.669479 2519.691723 2620.060557 2636.658579 1689.578559 2601.909062 2977.079011 0.914731042 0.785446141 0.804650101 0.875579543 0.846363739 0.880077602 0.885652873 0.567528962 0.87398052 1 11.5396818 -1.000000002 0.07208357 1.199698364 0.021133785 0.281655086 0.091160836 136.0638246 0.729479109 2.068019443 16.28450554 0.1 1.000000002 -1.178564579 GTTAVLTEK ddPTM_HeLa_Curcumin_4h_R1 1 GTTAVLTEK 9 0 Q99436 Q99436 PSMB7 Proteasome subunit beta type-7 0 0 120.99 0.0012774 3981100 712.52 816.52 657.88 635.3 667.6 1044.4 708.43 771.31 893.8 766.93 FALSE FALSE TRUE 656.1232902 887.0963505 682.2616115 632.6712969 659.639306 827.7796672 728.3066392 1006.478868 795.7523762 793.5807604 0.826788303 1.117840042 0.859725494 0.797236184 0.831218874 1.043094425 0.917747349 1.268275289 1.002736477 1 9.632233239 GTVEPQLEAR ddPTM_HeLa_Curcumin_4h_R1 2 GTVEPQLEAR 10 0 P21333-2;P21333;F8WE98;A0A669KBC6;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 110.39 0.0052431 8987200 2099.6 1322.47 2082.4 1697.14 2349.4 2546.6 2149.5 2177.9 1472.73 1395.42 FALSE FALSE TRUE 1933.414445 1436.778414 2159.575576 1690.117684 2321.384939 2018.406454 2209.809185 2841.931684 1311.175204 1443.910741 1.33901244 0.99506041 1.495643404 1.170513963 1.607706677 1.397874811 1.530433372 1.968218397 0.9080722 1 10.49576585 -1 0.213058057 1.059216072 4.970549259 0.695923643 0.172627044 22.21246959 0.262234849 0.131220201 29.83715722 0.1 1 3.911333186 GTVGEPTYDAEFQHFLR ddPTM_HeLa_Curcumin_4h_R1 1 GTVGEPTYDAEFQHFLR 17 0 Q14204;A0A2R8Y706;A0A2R8Y542;A0A2R8Y5T0 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 0 85.988 0.0050596 4631200 1606.6 1447.2 1830.3 1939 1389.1 2111.8 1772.9 1576.8 1629.9 1881.1 FALSE FALSE TRUE 1479.435915 1572.289519 1898.132528 1930.976932 1372.53589 1673.788875 1822.642802 2057.559061 1451.104048 1946.468085 0.760061738 0.807765373 0.975167557 0.992041404 0.705141739 0.859910773 0.936384633 1.057073104 0.745506211 1 10.92664297 -4.35978783 2.853605966 0.878519608 1.070340677 0.249570221 0.102155038 0.443962008 5.516530472 0.015886087 0.173630277 4.37E-05 4.35978783 0.191821069 GTVPDDAVEALADS(ph)LGKK ddPTM_HeLa_Curcumin_4h_R1 2 GTVPDDAVEALADSLGKK 18 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E7EVY3;E9PCH5;P20810-3;E7EQ12;E7EQA0;H0Y7F0;A0A0A0MR45;H0Y9H6;H0YD33 P20810-6 CAST Calpastatin 1 0 GTVPDDAVEALADS(1)LGKK;GTVPDDAVEALADS(1)LGKK ; 152.63 3.02E-05 48231000 6773.4 5693.5 5575 6178.2 5785.3 8336.4 7188.3 7034.5 6795.3 5602.8 TRUE FALSE FALSE 6237.278243 6185.62077 5781.614404 6152.636245 5716.314076 6607.336669 7389.984352 9179.286667 6049.872591 5797.496883 1.07585711 1.066946804 0.997260459 1.061257362 0.985996921 1.139687835 1.274685351 1.583318948 1.04353184 1 12.50121442 -4.296968611 1.328733488 1.034687716 1.797241966 0.962583412 0.03352498 0.179871811 0.284487736 0.005615029 0.18128222 5.05E-05 4.296968611 0.76255425 GTVTDFPGFDER ddPTM_HeLa_Curcumin_4h_R1 3 GTVTDFPGFDER 12 0 P08758;D6RBE9;E9PHT9;D6RCN3 P08758 ANXA5 Annexin A5;Annexin 0 0 ;; ;; 247.22 9.52E-39 105185400 17705.8 11624.5 15883 14183.3 14709.2 18987.3 14419.8 15749.2 14526.1 14242.9 FALSE FALSE TRUE 16304.36725 12629.26998 16471.63795 14124.61326 14533.8024 15049.11995 14824.38078 20551.05858 12932.62317 14737.83971 1.106292887 0.856928168 1.117642631 0.958391022 0.986155548 1.021121158 1.005872032 1.394441721 0.877511455 1 13.84723745 -4.25930909 24.88422634 1.028197367 1.394441856 0.643774194 0.086094586 76.92432545 898496.7771 0.010036458 0.087993343 5.50E-05 4.25930909 0.366244489 GTVTDFPGFDERADAETLR ddPTM_HeLa_Curcumin_4h_R1 1 GTVTDFPGFDERADAETLR 19 1 P08758;D6RBE9;E9PHT9;D6RCN3 P08758 ANXA5 Annexin A5;Annexin 0 0 74.726 0.0062628 3351800 1531.1 1131.1 1096.3 1390.4 923.77 1632.9 1076.2 1018.6 1899.2 1415.1 FALSE FALSE TRUE 1409.911819 1228.867244 1136.929842 1384.646893 912.7546461 1294.218133 1106.395276 1329.166451 1690.862512 1464.27462 0.962873904 0.839232769 0.776445775 0.945619677 0.623349359 0.883862983 0.755592742 0.907730308 1.154744123 1 10.51597044 -7.262010151 2.817107839 0.984727205 0.812088118 0.480523435 0.100731965 0.161954375 2.509272524 0.013567158 0.016066653 5.47E-08 7.262010151 -0.172639087 GTYVPSS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 4 GTYVPSSPTR 10 0 Q9Y4P8-4;Q9Y4P8 Q9Y4P8-4 WIPI2 WD repeat domain phosphoinositide-interacting protein 2 1 0 GTYVPS(0.003)S(0.964)PT(0.034)R;GTYVPS(0.003)S(0.958)PT(0.039)R;GTYVPS(0.004)S(0.854)PT(0.142)R;GTYVPS(0.003)S(0.967)PT(0.029)R ;;; 131.42 0.0027192 642420000 26772.8 21727.8 23277.6 24029 24107.3 28829.3 21411.4 24837.7 25919.7 24751.2 TRUE FALSE FALSE 24653.70463 23605.85421 24140.28833 23929.57436 23819.83619 22849.77821 22012.14626 32410.60039 23076.37376 25611.30236 0.962610346 0.921696753 0.942563873 0.934336491 0.930051735 0.892175567 0.859470009 1.26548037 0.90102305 1 14.644493 -8.606271916 0.97522582 0.996008081 0.954175771 0 0.109973743 1.698262935 3.272907206 0.037771273 0.019839646 2.48E-09 8.606271916 -0.04183231 GVAGPGPIGREPDPDS(ph)DWEPEER ddPTM_HeLa_Curcumin_4h_R1 2 GVAGPGPIGREPDPDSDWEPEER 23 1 Q9NPE2-3;Q9NPE2 Q9NPE2-3 NGRN Neugrin 1 0 GVAGPGPIGREPDPDS(1)DWEPEER;GVAGPGPIGREPDPDS(1)DWEPEER ; 107.58 8.52E-06 51762000 3862.2 3183.1 3419.7 3913.7 3823 5457.7 3529.6 2929.8 4528.8 3266.6 TRUE FALSE FALSE 3556.502795 3458.23298 3546.43709 3897.506146 3777.413222 4325.711499 3628.631077 3823.082533 4032.00197 3380.114107 1.052184241 1.023111313 1.049206322 1.1530694 1.117540149 1.279753098 1.073523249 1.131051323 1.192859721 1 11.72285623 -6.325014139 3.074014886 1.025333227 1.153349875 0.186556222 0.073259857 0.138372965 2.584093786 0.007870636 0.01270643 4.73E-07 6.325014139 0.128016649 GVAINFVK ddPTM_HeLa_Curcumin_4h_R1 1 GVAINFVK 8 0 I3L3H2;P38919 I3L3H2 EIF4A3 "Eukaryotic initiation factor 4A-III;Eukaryotic initiation factor 4A-III, N-terminally processed" 0 0 111.28 0.002052 0 455.76 694.79 598.29 632.48 528.98 814.81 677.71 695.04 386 435.18 FALSE FALSE TRUE 419.6861151 754.8445517 620.4631537 629.8629653 522.672259 645.8092212 696.7247186 906.9544964 343.6567657 450.3024726 0.932009351 1.676305589 1.37788085 1.398755289 1.160713722 1.434167611 1.54723716 2.014100636 0.763168729 1 8.814750589 -1 0.19921159 0.89296859 5.495933871 0.626666139 0.217766259 25.97622264 0.29741438 0.221003103 37.56520426 0.1 1 4.60296528 GVAPADS(ph)PEAPR ddPTM_HeLa_Curcumin_4h_R1 4 GVAPADSPEAPR 12 0 Q9P2G1 Q9P2G1 ANKIB1 Ankyrin repeat and IBR domain-containing protein 1 1 0 GVAPADS(1)PEAPR;GVAPADS(1)PEAPR;GVAPADS(1)PEAPR;GVAPADS(1)PEAPR ;;; 187.74 1.50E-05 157438200 9810.8 7377 8933.1 8256 8836.2 9584.3 6694.5 3995.46 8876.9 8828.9 TRUE FALSE FALSE 9034.264828 8014.635009 9264.168544 8221.83886 8730.834086 7596.408143 6882.329653 5213.657361 7903.126279 9135.703618 0.988896445 0.877287108 1.014061854 0.899967775 0.95568272 0.831507726 0.753344235 0.570690292 0.865081291 1 13.15730013 -3.736838228 0.594463734 0.988963425 3.41E-20 0.802904996 0.056934228 1.087594617 0.169477859 0.006990733 0.849232648 0.0001833 3.736838228 -0.988963425 GVAPADS(ph)PEAPRR ddPTM_HeLa_Curcumin_4h_R1 3 GVAPADSPEAPRR 13 1 Q9P2G1 Q9P2G1 ANKIB1 Ankyrin repeat and IBR domain-containing protein 1 1 0 GVAPADS(1)PEAPRR;GVAPADS(1)PEAPRR;GVAPADS(1)PEAPRR ;; 167.22 0.00029107 91584700 9023.3 7597.7 7612 8105.2 7477.6 9909 5821.4 3782.18 8500.2 8177.3 TRUE FALSE FALSE 8309.096284 8254.411333 7894.107416 8071.66283 7388.434504 7853.761703 5984.732817 4935.349271 7567.749326 8461.460566 0.981993146 0.97553032 0.932948556 0.953932571 0.873186662 0.928180382 0.707293117 0.58327392 0.894378608 1 13.046691 -3.761755845 0.62416851 0.988423747 9.74E-13 0.876370801 0.044828813 0.831601771 0.144126378 0.005537579 0.678163964 0.000173079 3.761755845 -0.988423747 GVDEATIIDILTKR ddPTM_HeLa_Curcumin_4h_R1 2 GVDEATIIDILTKR 14 1 P04083;Q5T3N1;Q5T3N0 P04083 ANXA1 Annexin A1;Annexin 0 0 ; ; 219.97 6.50E-14 62314000 5960.5 5189.7 5089.6 5046.3 4193 6520.7 4694.8 5370.9 7194 5732.9 FALSE FALSE TRUE 5488.720136 5638.274543 5278.225053 5025.419748 4143.001214 5168.233317 4826.523453 7008.462685 6404.836199 5932.117848 0.925254736 0.9504657 0.889770768 0.847154402 0.698401704 0.871229036 0.813625686 1.181443603 1.079687957 1 12.53433154 -7.774942849 0.719945023 0.986155184 0.874405212 0.159361091 0.119510521 0.888847191 1.016944178 0.036872611 0.030790312 1.68E-08 7.774942849 -0.111749972 GVDEVTIVNILTNR ddPTM_HeLa_Curcumin_4h_R1 3 GVDEVTIVNILTNR 14 0 H0YMW4;P07355;H0YN42;H0YMU9;H0YMD0;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;P07355-2 H0YMW4;P07355;P07355-2 ANXA2 Annexin;Annexin A2 0 0 ;; ;; 168.98 0.0017578 4786400 1331.06 905.79 1538.391 1246.19 1065.05 781.06 630.78 523.85 456.26 197.928 FALSE FALSE TRUE 1225.705196 984.0824515 1595.405124 1241.033596 1052.349974 619.0593516 648.4779891 683.5694535 406.2094195 204.8059833 5.98471381 4.804949718 7.789836499 6.059557324 5.138277493 3.022662433 3.166303927 3.337643962 1.983386486 1 7.678114053 -1.472521047 19.51309186 4.010395783 3.331729265 0 1.989888254 0 0 0.326191373 0 0.033688289 1.472521047 -0.678666518 GVDFES(ph)SEDDDDDPFMNT(ph)SSLRR ddPTM_HeLa_Curcumin_4h_R1 3 GVDFESSEDDDDDPFMNTSSLRR 23 1 F8W7U8;P49959-2;P49959;P49959-3 F8W7U8 MRE11A Double-strand break repair protein MRE11A 2 0 GVDFES(0.95)S(0.051)EDDDDDPFMNT(0.376)S(0.331)S(0.292)LRR;GVDFES(0.75)S(0.25)EDDDDDPFMNT(0.393)S(0.33)S(0.277)LRR;GVDFES(0.68)S(0.32)EDDDDDPFMNT(0.386)S(0.33)S(0.284)LRR ;; 80.944 0.00026241 42897000 4358.72 3355.95 3231.31 3582.46 3486.32 4272.85 3268.4 3583.39 4487.8 3710.64 TRUE FALSE FALSE 4013.722713 3646.023364 3351.065191 3567.63673 3444.747911 3386.612745 3360.102508 4675.949115 3995.499568 3839.584464 1.04535341 0.949588008 0.872767671 0.929172613 0.897166853 0.882025849 0.875121394 1.217826866 1.040607286 1 11.90673447 -7.169378344 5.654013255 1.021317774 0.934885542 0.125139595 0.096551404 0.318012375 15.6751043 0.015225516 0.01868931 6.77E-08 7.169378344 -0.086432232 GVDFES(ph)SEDDDDDPFMNTS(ph)SLRR ddPTM_HeLa_Curcumin_4h_R1 1 GVDFESSEDDDDDPFMNTSSLRR 23 1 F8W7U8;P49959-2;P49959;P49959-3 F8W7U8 MRE11A Double-strand break repair protein MRE11A 2 0 GVDFES(0.709)S(0.291)EDDDDDPFMNT(0.181)S(0.442)S(0.377)LRR 73.603 0.0005101 18749000 1212.4 851.95 807.62 769.95 722.87 1450.4 685.52 793.3 1497.2 942.63 TRUE FALSE FALSE 1116.437261 925.5887618 837.5511077 766.7641509 714.2502474 1149.570691 704.7538462 1035.173518 1332.960906 975.3863223 1.14461033 0.948945808 0.858686541 0.78611329 0.732274209 1.178579876 0.722538168 1.061295914 1.366597906 1 9.929829932 -7.050893339 5.036960963 1.067983059 0.884583554 0.313513557 0.166520087 0.199433019 11.24297518 0.022142312 0.02762658 8.89E-08 7.050893339 -0.183399505 GVDFESS(ph)EDDDDDPFMNT(ph)SSLRR ddPTM_HeLa_Curcumin_4h_R1 1 GVDFESSEDDDDDPFMNTSSLRR 23 1 F8W7U8;P49959-2;P49959;P49959-3 F8W7U8 MRE11A Double-strand break repair protein MRE11A 2 0 GVDFES(0.262)S(0.738)EDDDDDPFMNT(0.376)S(0.331)S(0.292)LRR 52.192 0.0098829 3280500 844.04 728.58 715.09 736.55 691.27 1065.2 701.24 860.87 1043.3 807.64 TRUE FALSE FALSE 777.2333434 791.5552087 741.5918645 733.5023513 683.0270567 844.2655127 720.9149071 1123.3453 928.8526002 835.7054299 0.930032659 0.947170116 0.887384284 0.877704422 0.817305994 1.010242943 0.862642363 1.344188107 1.111459334 1 9.706850699 -4.254521968 24.89640116 0.941462432 1.344188304 0.692458728 0.081139717 275.5743964 991790.7348 0.009132619 0.121378928 5.57E-05 4.254521968 0.402725872 GVDLLLEGVQGES(ph)SPTRR ddPTM_HeLa_Curcumin_4h_R1 2 GVDLLLEGVQGESSPTRR 18 1 F5H7T0;F6RJM5;Q96S38-2;Q96S38 F5H7T0 RPS6KC1 Ribosomal protein S6 kinase delta-1 1 0 GVDLLLEGVQGES(0.801)S(0.197)PT(0.002)RR;GVDLLLEGVQGES(0.928)S(0.071)PT(0.001)RR ; 80.41 0.0029363 8452400 3983.5 3465.6 3721.5 3551 3383.6 4278.7 3329.7 3071.6 4505.9 3469.5 TRUE FALSE FALSE 3668.201772 3765.151022 3859.422064 3536.306903 3343.25278 3391.249389 3423.122421 4008.1167 4011.614043 3590.064867 1.021764761 1.048769635 1.075028504 0.985025907 0.931251357 0.944620645 0.953498766 1.116446875 1.117421047 1 11.8097942 -6.028207835 24.78029359 1.018956179 0.978240591 0.120823643 0.060948279 1045.925139 918833.1188 0.007814019 0.012977192 9.37E-07 6.028207835 -0.040715587 GVDPNSRNS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 GVDPNSRNSSR 11 1 Q9UK76;J3KT51;Q9UK76-2;F2Z3M5 Q9UK76 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 1 0 GVDPNS(0.035)RNS(0.813)S(0.152)R 71.031 0.016963 15374000 581.67 773.47 441.08 461.81 390.6 890.28 853.71 248.98 382.31 664.62 TRUE FALSE FALSE 535.6302057 840.3253003 457.4268128 459.8991526 385.9423501 705.6258925 877.662805 324.8928558 340.3715495 687.7154955 0.778854351 1.221908341 0.665139605 0.668734608 0.561194786 1.026043323 1.276200421 0.472423346 0.494930755 1 9.425668042 -9.543712682 0.954325617 1.013993908 0.839547583 0 0.299660089 1.953312228 2.73398579 0.263400367 0.045012577 2.86E-10 9.543712682 -0.174446325 GVEEEEEDGEMRE ddPTM_HeLa_Curcumin_4h_R1 10 GVEEEEEDGEMRE 13 1 P62306 P62306 SNRPF Small nuclear ribonucleoprotein F 0 0 ;;;;;;;;; ;;;;;;;;; 257.92 1.52E-35 82978430 14127.64 11001.45 12524.38 13022.6 11932.83 16951.06 12472.29 11633.25 13350.8 11763.28 FALSE FALSE TRUE 13009.42239 11952.36632 12988.54454 12968.71593 11790.5388 13435.21908 12822.22889 15180.17437 11886.25064 12172.0531 1.068794416 0.981951542 1.067079188 1.06545016 0.968656536 1.103775917 1.053415458 1.247133433 0.976519782 1 13.57128491 GVEFPMADLDALS(ph)PIHT(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 1 GVEFPMADLDALSPIHTPQR 20 0 Q6ZVM7-2;Q6ZVM7-5;Q6ZVM7 Q6ZVM7-2 TOM1L2 TOM1-like protein 2 2 0 GVEFPMADLDALS(1)PIHT(1)PQR 63.559 0.0065732 3843600 1674.5 1598 1527 1522.2 1627.7 2929.9 3061.3 1486.8 1618.8 1212.2 TRUE FALSE FALSE 1541.961558 1736.123999 1583.591963 1515.90154 1608.290741 2322.205713 3147.191839 1940.118476 1441.22169 1254.32386 1.229316931 1.384111437 1.26250645 1.208540783 1.282197359 1.851360552 2.509074363 1.546744456 1.14900285 1 10.29269418 -5.241193529 3.138647302 1.156020309 2.057505768 0.67579886 0.238820118 0.095413316 1.916910858 0.033344595 0.090229999 5.74E-06 5.241193529 0.901485459 GVEGLIDIENPNR ddPTM_HeLa_Curcumin_4h_R1 1 GVEGLIDIENPNR 13 0 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 0 0 112.13 0.0016988 542480 338.5 195.5 175.7 204.52 282.62 257.5 221.5 213.5 364.13 315.01 FALSE FALSE TRUE 311.7073678 212.3981489 182.2115966 203.6737504 279.2499411 204.0915974 227.7146939 278.5951672 324.18585 325.9565741 0.956284955 0.651614865 0.559005742 0.624849341 0.856709032 0.626131251 0.698604391 0.854700256 0.994567608 1 8.348535962 -7.293889592 6.75392546 0.979906779 0.6914968 0.676768795 0.091076161 0.08535756 13.32394833 0.015627321 0.017993071 5.08E-08 7.293889592 -0.288409979 GVEICIATPGR ddPTM_HeLa_Curcumin_4h_R1 1 GVEICIATPGR 11 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2;P17844-2;P17844;J3KTA4;J3KRZ1;J3QSF1 A0A1X7SBZ2;P17844-2 DDX17;DDX5 Probable ATP-dependent RNA helicase DDX17;Probable ATP-dependent RNA helicase DDX5 0 0 94.409 0.016182 2637900 848.21 697.06 757.63 1011.5 997.74 1039.4 927.06 917.32 988.5 877.35 FALSE FALSE TRUE 781.0732835 757.3107604 785.7084343 1007.314681 985.8426021 823.8167235 953.0708085 1197.006645 880.0640231 907.8378472 0.860366514 0.83419166 0.865472217 1.109575553 1.085923665 0.907449195 1.049824935 1.318524722 0.969406625 1 9.826290824 -6.256123332 24.88370878 0.918631375 1.08094956 0.439635466 0.105312396 381.3993993 1785277.793 0.017031229 0.027692002 5.54E-07 6.256123332 0.162318185 GVEPSPS(ph)PIKPGDIK ddPTM_HeLa_Curcumin_4h_R1 2 GVEPSPSPIKPGDIK 15 1 Q92890-3;Q92890;Q92890-1;C9JNP9 Q92890-3 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 0 GVEPS(0.166)PS(0.834)PIKPGDIK;GVEPS(0.087)PS(0.913)PIKPGDIK ; 137.27 0.0056069 139879000 5380.6 4852.7 4571.3 5144.8 5961.2 6134.6 5317.7 2281.98 4735 4041.9 TRUE FALSE FALSE 4954.719832 5272.145765 4740.716399 5123.512181 5890.116583 4862.214809 5466.90035 2977.745197 4215.582346 4182.355724 1.184672027 1.260568472 1.13350387 1.225030227 1.40832511 1.162554103 1.307134235 0.711977984 1.007944475 1 12.03010006 -9.008537876 0.813923192 1.000000266 1.188685693 0.12768518 0.173349631 0.946872873 1.14815671 0.106469979 0.032960287 9.81E-10 9.008537876 0.188685428 GVEPSPS(ph)PIKPGDIKR ddPTM_HeLa_Curcumin_4h_R1 2 GVEPSPSPIKPGDIKR 16 2 Q92890-3;Q92890;Q92890-1 Q92890-3 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 0 GVEPS(0.036)PS(0.964)PIKPGDIKR;GVEPS(0.016)PS(0.984)PIKPGDIKR ; 102.84 0.0015679 490200000 7534.8 6480.8 6042.6 7496.5 6705 8554 5961 2846 7639 6218.5 TRUE FALSE FALSE 6938.412629 7040.971474 6266.544072 7465.481469 6625.047254 6779.803977 6128.249617 3713.732299 6801.020812 6434.592412 1.078298699 1.094237369 0.973883608 1.160210467 1.029598587 1.053649329 0.952391266 0.577151133 1.056946637 1 12.65163305 -4.248087529 2.491911508 1.046471118 0.463710221 0.894054241 0.049295818 0.128046605 0.952597661 0.007097405 0.160000766 5.65E-05 4.248087529 -0.582760897 S(ph)PLSPTETFSWPDVR ddPTM_HeLa_Curcumin_4h_R1 3 SPLSPTETFSWPDVR 15 0 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 0 S(0.999)PLSPTETFSWPDVR;S(0.885)PLS(0.112)PT(0.003)ETFSWPDVR;S(1)PLSPTETFSWPDVR ;; 230.23 6.86E-21 55961000 2299.65 1792 2249.35 2132.07 2528.35 2404.71 1281.18 364.73 2301.32 2196.73 TRUE FALSE FALSE 2117.630276 1946.892495 2332.71289 2123.248059 2498.201078 1905.946039 1317.126463 475.934498 2048.870954 2273.066204 0.931618389 0.856504967 1.026240628 0.934089845 1.099044574 0.838491213 0.57944923 0.209379954 0.901368799 1 11.15042399 -4.498097403 1.731546641 0.96840023 0.127842495 0.925010138 0.067866004 0.099896876 0.412083329 0.009304026 0.118304971 3.18E-05 4.498097403 -0.840557735 down GVGDDQLGEESEERDDHLLPM ddPTM_HeLa_Curcumin_4h_R1 1 GVGDDQLGEESEERDDHLLPM 21 1 H0YF90;F5GX30;P20645 H0YF90 M6PR Cation-dependent mannose-6-phosphate receptor 0 0 88.264 0.00053476 4192600 2496.3 2319.9 2313.4 2623 2365.3 1992.8 797.39 344.35 3277.7 2640.6 FALSE FALSE TRUE 2298.715221 2520.421819 2399.136639 2612.146721 2337.095342 1579.470817 819.7626173 449.3407298 2918.14451 2732.360653 0.841292755 0.922433799 0.878045377 0.956003637 0.855339261 0.578060885 0.300019917 0.164451471 1.0679939 1 11.41593221 -4.928430999 1.547577791 0.922789276 0.152767909 0.954533203 0.062024651 0.064497554 0.272417744 0.009142159 0.051234891 1.18E-05 4.928430999 -0.770021368 down GVGQADWT(ph)PDLGLR ddPTM_HeLa_Curcumin_4h_R1 2 GVGQADWTPDLGLR 14 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 GVGQADWT(1)PDLGLR;GVGQADWT(1)PDLGLR ; 165.89 0.00062207 25481700 4617.1 3941.6 4425.1 4863.4 3839.2 7193.4 5948.1 2196.47 4914 3983.2 TRUE FALSE FALSE 4251.651663 4282.294341 4589.098099 4843.276539 3793.420047 5701.407754 6114.987678 2866.163592 4374.946494 4121.615904 1.031549703 1.038984331 1.113422067 1.175091676 0.920372042 1.383294292 1.483638413 0.695398033 1.061463901 1 12.00899435 -6.527407732 0.857839723 1.010727397 1.171512807 0.035498522 0.207910779 1.028366286 1.512027008 0.039049606 0.073466553 2.97E-07 6.527407732 0.16078541 GVGS(ph)PEPGPTAPYLGR ddPTM_HeLa_Curcumin_4h_R1 1 GVGSPEPGPTAPYLGR 16 0 Q9C0B5;Q9C0B5-2 Q9C0B5 ZDHHC5 Palmitoyltransferase ZDHHC5 1 0 GVGS(0.999)PEPGPT(0.001)APY(0.001)LGR 97.223 0.0036296 2799600 1819.7 1655.6 1680 1975 1665.7 2657.1 1627.7 968.81 2411.5 1585 TRUE FALSE FALSE 1675.668825 1798.702687 1742.262278 1966.827973 1645.837615 2105.987508 1673.368881 1264.195709 2146.964483 1640.078632 1.021700297 1.096717347 1.062304114 1.199227851 1.003511407 1.284077158 1.020297959 0.770814084 1.30906192 1 10.67954927 -7.40999901 4.624060725 1.009281705 1.072207078 0 0.158104873 0.587432606 19.53987885 0.021367962 0.024177401 3.89E-08 7.40999901 0.062925372 GVGSGPHPPDTQQPS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 GVGSGPHPPDTQQPSPSK 18 0 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 0 GVGSGPHPPDTQQPS(0.96)PS(0.04)K;GVGSGPHPPDT(0.297)QQPS(0.558)PS(0.145)K ; 242.09 6.05E-32 41160000 6561 5242.65 5891.2 5254.7 7238.6 8661.8 5547.2 2301.83 7777.8 5641.6 TRUE FALSE FALSE 6041.689927 5695.801305 6109.533054 5232.957444 7152.284423 6865.245041 5702.839502 3003.647371 6924.594799 5837.64518 1.034953263 0.975701868 1.046574923 0.896415812 1.225200265 1.17602986 0.976907525 0.51453065 1.186196589 1 12.51117081 -4.271096628 4.361582998 1.032218941 0.481207232 0.714479584 0.102391515 0.072414385 3.277535278 0.01240653 0.121128287 5.36E-05 4.271096628 -0.551011709 GVHIHQAGGS(ph)PPASSTSSSSLTNDVAK ddPTM_HeLa_Curcumin_4h_R1 1 GVHIHQAGGSPPASSTSSSSLTNDVAK 27 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 0 GVHIHQAGGS(0.982)PPAS(0.001)S(0.001)T(0.014)S(0.001)SSSLTNDVAK 128.51 8.89E-09 14244000 4783.3 4165.1 4691.2 4569 6234.7 6664.7 5295.3 3993.7 5442.5 4974.8 TRUE FALSE FALSE 4404.696758 4525.112685 4865.059999 4550.094689 6160.355275 5282.366093 5443.871866 5211.360745 4845.471366 5147.67393 0.855667398 0.879059697 0.945098712 0.883912763 1.196726008 1.026165636 1.057540151 1.01237196 0.941293375 1 12.32970496 -5.785935032 24.99997433 0.923966346 1.068722727 0.6143712 0.060257803 143.1804466 146127.924 0.010567205 0.019161011 1.64E-06 5.785935032 0.144756382 GVHIHQAGGSPPASSTS(ph)SSSLTNDVAK ddPTM_HeLa_Curcumin_4h_R1 1 GVHIHQAGGSPPASSTSSSSLTNDVAK 27 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 0 GVHIHQAGGS(0.003)PPAS(0.108)S(0.108)T(0.108)S(0.416)S(0.041)S(0.041)S(0.158)LT(0.019)NDVAK 69.876 0.00015718 12479000 2801.1 2549.9 2419.7 2089.9 3151.9 3808.4 2099.7 1887.8 3073.2 2202.8 TRUE FALSE FALSE 2579.389979 2770.301994 2509.376211 2081.252548 3114.315651 3018.49491 2158.611931 2463.38153 2736.077649 2279.347136 1.131635431 1.215392754 1.100918842 0.913091523 1.366319154 1.324280476 0.947030795 1.080739959 1.200377777 1 11.15440494 -9.036372654 0.733848939 0.995273081 1.137113183 0 0.149253885 1.306698957 1.233763212 0.107415699 0.029271193 9.20E-10 9.036372654 0.141840102 GVIS(ph)TPVIR ddPTM_HeLa_Curcumin_4h_R1 1 GVISTPVIR 9 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;A0A494C0Y9;A0A0C4DG79 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 0 GVIS(0.871)T(0.129)PVIR 123.21 0.0054044 10701000 4882.8 4542 4355.4 4981.7 4810 8512.7 8329.7 2976.9 4946.6 3777.6 TRUE FALSE FALSE 4496.321228 4934.590241 4516.814955 4961.087045 4752.643892 6747.070062 8563.408964 3884.543106 4403.970356 3908.871319 1.150286326 1.262407953 1.155529202 1.269186586 1.215860923 1.726091629 2.190762567 0.993776154 1.126660357 1 11.93253638 -5.350762945 3.69607333 1.112002651 1.693261268 0.352216065 0.283501527 0.152473019 3.890177279 0.038045041 0.091351295 4.46E-06 5.350762945 0.581258617 GVIST(ph)PVIR ddPTM_HeLa_Curcumin_4h_R1 1 GVISTPVIR 9 0 Q9NZB2-4;Q9NZB2;Q9NZB2-6;A0A494C0Y9;A0A0C4DG79 Q9NZB2-4 FAM120A Constitutive coactivator of PPAR-gamma-like protein 1 1 0 GVIS(0.063)T(0.937)PVIR 139.98 0.0069245 17374000 2455.7 2347.5 2304.8 2667.9 1961 4893.7 5181.4 1624.2 2779.5 1877.4 TRUE FALSE FALSE 2261.328754 2550.40744 2390.217916 2656.860937 1937.616356 3878.691457 5326.776139 2119.411103 2474.595804 1942.63951 1.164049605 1.312856774 1.230397046 1.367655153 0.997414263 1.996608962 2.742030166 1.090995572 1.273831707 1 10.92380249 -5.254998533 23.67574221 1.12670714 2.023093614 0.423362366 0.393147389 136.7664301 502731.3892 0.049907011 0.123767147 5.56E-06 5.254998533 0.896386474 GVITVK(ac)DGK ddPTM_HeLa_Curcumin_4h_R1 2 GVITVKDGK 9 1 P10809;E7EXB4 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 1 ; GVITVK(1)DGK;GVITVK(1)DGK 123.86 0.0010399 5530900 3932.2 4127.2 3838 4311.8 4335 6509.5 4563.7 4035.2 4691.2 3165.4 FALSE TRUE FALSE 3620.962221 4483.936778 3980.239656 4293.958914 4283.307956 5159.356323 4691.745139 5265.513904 4176.587097 3275.397414 1.105503169 1.368974879 1.215192892 1.310973409 1.307721603 1.575184831 1.432420115 1.607595427 1.275139035 1 11.67745425 -5.478616108 0.259280746 0.95838571 1.82701439 0.581874451 0.116483447 1.205308738 0.112041033 0.061060349 0.331396353 3.32E-06 5.478616108 0.868628681 GVLEGDDVLFYDES(ph)PPPRPK ddPTM_HeLa_Curcumin_4h_R1 1 GVLEGDDVLFYDESPPPRPK 20 1 Q5T670;Q7L590-2;Q7L590 Q5T670 MCM10 Protein MCM10 homolog 1 0 GVLEGDDVLFY(0.004)DES(0.996)PPPRPK 60.761 0.0069486 6621700 966.66 729.59 837.51 994.18 1056 1664.4 1477.1 629.98 1161.9 1108.2 TRUE FALSE FALSE 890.147841 792.6525086 868.5488573 990.0663466 1043.40789 1319.184678 1518.543451 822.0580019 1034.442477 1146.709868 0.776262476 0.69124068 0.757426863 0.863397425 0.90991446 1.150408413 1.324261257 0.716884039 0.90209608 1 10.1632847 -5.38965878 4.703157928 0.862508589 1.088491206 0.272665342 0.163168885 0.238488754 8.084227512 0.024513439 0.056226596 4.08E-06 5.38965878 0.225982618 GVLFYGPPGCGK ddPTM_HeLa_Curcumin_4h_R1 2 GVLFYGPPGCGK 12 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 ; ; 174.16 5.04E-07 8555000 6580.1 5179.4 5582.7 5560.8 5643.7 6976.8 5606.8 5023 6398.7 5623.2 FALSE FALSE TRUE 6059.278142 5627.084257 5789.599773 5537.790883 5576.402564 5529.733035 5764.111718 6554.489577 5696.778619 5818.605781 1.041362548 0.967084636 0.995014956 0.951738456 0.958374355 0.950353614 0.990634515 1.126470812 0.979062482 1 12.50645779 -7.259510001 24.94938116 1.019532314 0.987120382 0 0.050813911 338.2780834 4374336.402 0.008334382 0.009918209 5.50E-08 7.259510001 -0.032411932 GVLLFGPPGTGK ddPTM_HeLa_Curcumin_4h_R1 2 GVLLFGPPGTGK 12 0 P35998;P35998-2 P35998 PSMC2 26S protease regulatory subunit 7 0 0 ; ; 137.46 0.00021729 1053380 1523.04 1194.35 1712.75 1124.3 1685.39 1893.01 1333.73 1503.5 1264.03 987.15 FALSE FALSE TRUE 1402.489777 1297.584292 1776.226022 1119.647945 1665.292825 1500.378387 1371.150874 1961.910229 1125.369071 1021.453389 1.373033554 1.270331379 1.738920288 1.096132194 1.630317 1.468866229 1.342352856 1.920704606 1.101733161 1 9.996407657 -11.21425253 0.105189888 1.21E-13 1.875825956 0.462257881 0.20813836 36.983762 0.510028163 10.39339843 1.77652191 6.11E-12 11.21425253 1.875825956 GVLLYGPPGTGK ddPTM_HeLa_Curcumin_4h_R1 1 GVLLYGPPGTGK 12 0 P62195;J3QQM1;P62195-2;J3QRR3;J3QRW1;J3QLH6;J3KRP2;J3QSA9;Q8NB90-3;Q8NB90-2;Q8NB90 P62195;Q8NB90-3 PSMC5;SPATA5 26S protease regulatory subunit 8;Spermatogenesis-associated protein 5 0 0 140.45 5.42E-12 0 2622.1 2277.9 2585.9 2173.9 2608.8 2835.4 2381.7 1822.4 2462 2478.8 FALSE FALSE TRUE 2414.558018 2474.791526 2681.735729 2164.904978 2577.691764 2247.306078 2448.524092 2378.041371 2191.92476 2564.938115 0.941370867 0.964854283 1.045536231 0.844037899 1.004972303 0.876163859 0.954613321 0.927134014 0.854572181 1 11.3247083 -6.269636459 24.9993628 0.97592503 0.92536187 0.069667611 0.06139954 722.8830099 2204639.425 0.007083932 0.010934216 5.37E-07 6.269636459 -0.05056316 GVLMYGPPGTGK ddPTM_HeLa_Curcumin_4h_R1 1 GVLMYGPPGTGK 12 0 E9PM69;P17980;E9PMD8;E9PKD5;E9PN50;R4GNH3 E9PM69;E9PN50 PSMC3 26S protease regulatory subunit 6A 0 0 105.86 0.0047772 1183600 766.04 697.8 795.1 755.67 706.61 940.47 900.25 654.75 910.34 544.75 FALSE FALSE TRUE 705.4071257 758.1147227 824.5671054 752.5432378 698.1841373 745.4059207 925.5085921 854.3802609 810.4779796 563.680022 1.251431838 1.344938073 1.46282833 1.335053946 1.238617851 1.322391945 1.641904194 1.515718542 1.43783343 1 9.138732626 -9.833510574 0.067901678 4.40E-13 2.122919349 0 0.167100201 33.65775971 0.463100266 10.29028307 4.851296508 1.47E-10 9.833510574 2.122919349 GVNTFS(ph)PEGR ddPTM_HeLa_Curcumin_4h_R1 2 GVNTFSPEGR 10 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 0 GVNT(0.001)FS(0.999)PEGR;GVNT(0.002)FS(0.998)PEGR ; 168.85 0.00050946 463970000 7666.5 6034.8 6406.5 6678 6478.8 10456.4 7919.1 3942.5 7442 6120.6 TRUE FALSE FALSE 7059.688435 6556.421221 6643.930526 6650.368205 6401.544541 8287.624772 8141.288633 5144.550101 6625.631219 6333.290394 1.114695205 1.035231422 1.049048774 1.050065257 1.010777044 1.308581204 1.285475342 0.812302892 1.046159391 1 12.62873952 GVNTGAVGS(ph)YIYDRDPEGK ddPTM_HeLa_Curcumin_4h_R1 1 GVNTGAVGSYIYDRDPEGK 19 1 H0YFA4;P52943;P52943-2;H0YHD8 H0YFA4 CRIP2 Cysteine-rich protein 2 1 0 GVNT(0.234)GAVGS(0.754)Y(0.007)IY(0.004)DRDPEGK 54.656 0.013706 8656100 1689.7 1860.7 1902.9 1610.1 1915.8 3133 2423.9 2978 2204.5 1974.3 TRUE FALSE FALSE 1555.958462 2021.530617 1973.423148 1603.437833 1892.955336 2483.180484 2491.90811 3885.978491 1962.671865 2042.906778 0.761639483 0.989536399 0.965987861 0.784880568 0.92659898 1.215513361 1.219785522 1.902181016 0.960725123 1 10.99640766 -2.82833202 0.760031295 0.890021079 9.703327628 0.900677802 0.098009427 4.42873369 0.329884951 0.018317712 54.20441685 0.0014848 2.82833202 8.81330655 GVPAGNS(ph)DTEGGQPGR ddPTM_HeLa_Curcumin_4h_R1 3 GVPAGNSDTEGGQPGR 16 0 S4R3H4;E7EQT4;Q9UKV3;G3V3B0;Q9UKV3-3;Q9UKV3-2;Q9UKV3-5;G3V3T3 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 GVPAGNS(0.653)DT(0.347)EGGQPGR;GVPAGNS(0.999)DT(0.001)EGGQPGR;GVPAGNS(0.936)DT(0.064)EGGQPGR ;; 238.45 5.50E-30 164057600 1748.3 1531.51 1929.65 1634.23 1437.43 1804.52 1441.75 972.97 1920.48 1937.98 TRUE FALSE FALSE 1609.92021 1663.8869 2001.164526 1627.467989 1420.289586 1430.242211 1482.201625 1269.624074 1709.808149 2005.324661 0.802822726 0.829734423 0.997925456 0.811573318 0.708259173 0.713222272 0.739132996 0.633126445 0.852634081 1 10.96962011 -2.584204652 0.075813585 1.216665493 3.89E-15 0.531068373 0.077983608 71.03431632 0.552166291 1.907420628 9.690326656 0.002604926 2.584204652 -1.216665493 GVPAGNS(ph)DTEGGQPGRK ddPTM_HeLa_Curcumin_4h_R1 2 GVPAGNSDTEGGQPGRK 17 1 S4R3H4;E7EQT4;Q9UKV3;G3V3B0;Q9UKV3-3;Q9UKV3-2;Q9UKV3-5;G3V3T3 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 GVPAGNS(1)DTEGGQPGRK;GVPAGNS(1)DTEGGQPGRK ; 270.74 2.57E-52 35483500 4700.39 4195.52 4405.09 4388.94 3736.29 4145.97 3454.11 2227.84 4626.35 4875.98 TRUE FALSE FALSE 4328.349172 4558.162054 4568.346511 4370.779729 3691.737182 3286.049087 3551.02303 2907.09816 4118.85098 5045.419942 0.857876891 0.903425702 0.905444257 0.866286608 0.731700676 0.651293475 0.703811193 0.576185569 0.816354442 1 12.30075864 -3.221731088 0.232738986 0.986993162 1.11E-14 0.735491383 0.06422312 4.736590854 0.140862242 0.03870573 1.459661832 0.000600163 3.221731088 -0.986993162 GVPAGNSDT(ph)EGGQPGR ddPTM_HeLa_Curcumin_4h_R1 1 GVPAGNSDTEGGQPGR 16 0 S4R3H4;E7EQT4;Q9UKV3;G3V3B0;Q9UKV3-3;Q9UKV3-2;Q9UKV3-5;G3V3T3 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 GVPAGNS(0.326)DT(0.674)EGGQPGR 132.56 0.0013004 154930000 647.79 427.97 533.29 346.37 463.71 412.02 469.54 164.67 471.22 541.42 TRUE FALSE FALSE 596.516738 464.9618198 553.0541965 344.9368127 458.1805611 326.5624076 482.7140287 214.877125 419.5283449 560.2343047 1.064762962 0.829941715 0.987183741 0.615700984 0.817837389 0.582903269 0.86162883 0.383548674 0.748844441 1 9.129886516 -6.32945285 0.838550813 1.032266914 0.627842911 0.340865185 0.163615083 0.274271097 0.381971595 0.023915417 0.0523534 4.68E-07 6.32945285 -0.404424003 GVPPPEDLRS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 GVPPPEDLRSPSR 13 1 A0A1B0GUN5;Q5VTI5;Q9Y2H5 A0A1B0GUN5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 0 GVPPPEDLRS(0.824)PS(0.176)R 65.511 0.018518 7501600 6925.6 6131.7 6214.5 6723.2 6737.2 7827.7 6417.3 5003.5 6783.3 6177.6 TRUE FALSE FALSE 6377.431452 6661.696826 6444.814837 6695.38118 6656.86329 6204.146784 6597.352167 6529.044117 6039.188961 6392.27114 0.997678495 1.042148664 1.008219879 1.047418208 1.04139251 0.970570029 1.032082655 1.021396617 0.944764205 1 12.64211289 -7.297954543 24.1621565 0.99890373 1.022668039 0.278170714 0.026999382 418.310701 276795.9028 0.003436574 0.003929897 5.04E-08 7.297954543 0.023764309 GVPTGFILPIR ddPTM_HeLa_Curcumin_4h_R1 1 GVPTGFILPIR 11 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586;A0A494C1T2 V9GZ78 MTHFD1 "C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed" 0 0 93.649 0.016956 766370 0 130.26 118.35 0 0 163.23 173.61 128.06 135.58 0 FALSE FALSE TRUE 0 141.519094 122.7361551 0 0 129.374258 178.4810294 167.1049045 120.7072132 0 0 GVPVISVK(ac)TSGSK ddPTM_HeLa_Curcumin_4h_R1 1 GVPVISVKTSGSK 13 1 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 0 1 GVPVISVK(1)TSGSK 140.63 0.00051817 2929200 2952.8 2697.4 2476.2 2608.5 2778.7 2973.7 2719.2 2623.6 2915.8 2582.6 FALSE TRUE FALSE 2719.082764 2930.551237 2567.97015 2597.706718 2745.565817 2356.921099 2795.493434 3423.523562 2595.944035 2672.345158 1.01748936 1.09662153 0.960942542 0.97207006 1.027399402 0.881967321 1.046082474 1.281093332 0.971410458 1 11.38389064 -4.284546226 4.100784736 1.00234593 1.299034368 0.724207344 0.053058702 0.077211791 2.737770927 0.006824709 0.064400535 5.19E-05 4.284546226 0.296688438 GVQGGEK(ac)ALEICGAQR ddPTM_HeLa_Curcumin_4h_R1 2 GVQGGEKALEICGAQR 16 1 Q9H0U9 Q9H0U9 TSPYL1 Testis-specific Y-encoded-like protein 1 0 1 ; GVQGGEK(1)ALEICGAQR;GVQGGEK(1)ALEICGAQR 144.88 0.0017721 5356200 1078.42 980.59 1004.01 866.46 829.58 1456.89 937.58 1240.29 888.85 1061.56 FALSE TRUE FALSE 993.0619191 1065.34783 1041.219494 862.8748181 819.6878003 1154.714591 963.8859714 1618.448711 791.3453788 1098.449131 0.904058177 0.969865422 0.947899602 0.78553917 0.746222813 1.051222636 0.877497141 1.473394321 0.720420597 1 10.10125234 -4.257934291 24.93489213 0.93180895 1.473394533 0.699624735 0.111740254 123.6658098 879706.4088 0.012927753 0.127291767 5.52E-05 4.257934291 0.541585583 GVQKPAGPS(ph)TSPDGNSR ddPTM_HeLa_Curcumin_4h_R1 1 GVQKPAGPSTSPDGNSR 17 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 0 GVQKPAGPS(0.42)T(0.42)S(0.158)PDGNS(0.002)R 70.02 0.0085493 14022000 1116.6 1180.4 1334.5 1054 1400.2 1320.7 1094.4 958.48 1323.1 1206.4 TRUE FALSE FALSE 1028.219932 1282.428516 1383.957744 1049.638827 1383.50353 1046.771933 1125.105919 1250.71614 1177.95924 1248.32231 0.823681451 1.027321635 1.108654177 0.840839596 1.108290317 0.838542998 0.901294409 1.001917637 0.943633892 1 10.28577476 -9.93486468 2.196385653 1.000796801 0.929228023 0 0.104885162 0.861189595 7.534378928 0.084936717 0.016057716 1.16E-10 9.93486468 -0.071568779 GVQKPAGPST(ph)SPDGNSR ddPTM_HeLa_Curcumin_4h_R1 1 GVQKPAGPSTSPDGNSR 17 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 0 GVQKPAGPS(0.076)T(0.846)S(0.076)PDGNS(0.002)R 77.668 0.0090502 12383000 2333 1808 2042.8 1882.7 2012.4 2473.7 1608.8 906.48 2553.5 2215.6 TRUE FALSE FALSE 2148.340588 1964.275464 2118.507965 1874.909886 1988.403444 1960.626736 1653.938598 1182.861579 2273.387439 2292.591935 0.937079362 0.856792451 0.924066744 0.817812301 0.867316775 0.855200922 0.721427382 0.515949464 0.991623238 1 11.16276387 -3.528182347 0.401971762 0.971740762 9.72E-32 0.863017056 0.050359649 2.382891788 0.17008917 0.013582259 1.260746117 0.000296359 3.528182347 -0.971740762 GVQVETIS(ph)PGDGR ddPTM_HeLa_Curcumin_4h_R1 1 GVQVETISPGDGR 13 0 Q1JUQ3;A0A087WTS4;A0A087WV48;A0A087WZM5;P62942 Q1JUQ3 FKBP12-Exin;FKBP1A Peptidyl-prolyl cis-trans isomerase;Peptidyl-prolyl cis-trans isomerase FKBP1A 1 0 GVQVET(0.014)IS(0.986)PGDGR 83.869 0.018368 21262000 1616.5 1607.3 1502.3 1337.7 1440.6 1778.8 1628.4 1561.8 1693.2 1768 TRUE FALSE FALSE 1488.552319 1746.22785 1557.97656 1332.164952 1423.421786 1409.856829 1674.088521 2037.98563 1507.460196 1829.437868 0.813666507 0.954516073 0.851614907 0.72818267 0.778065115 0.770650293 0.915083562 1.113995542 0.824001854 1 10.8371847 -9.414122656 0.986930331 1.005470573 0.855207231 0 0.118528568 0.800155697 1.309432238 0.089738819 0.019602174 3.85E-10 9.414122656 -0.150263342 GVS(ph)GDRDENSFSLNSSISSSAR ddPTM_HeLa_Curcumin_4h_R1 2 GVSGDRDENSFSLNSSISSSAR 22 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 GVS(0.996)GDRDENS(0.004)FSLNSSISSSAR;GVS(0.997)GDRDENS(0.003)FSLNSSISSSAR ; 88.951 0.00017567 19187400 511.19 385.56 524.82 456.842 432.12 418.11 448.35 434.06 404.74 181.18 TRUE FALSE FALSE 470.7287721 418.8860884 544.2702909 454.9517089 426.9672512 331.3892729 460.9294943 566.4028958 360.3410346 187.4759915 2.510874957 2.234345235 2.903146619 2.426719844 2.27745029 1.767635793 2.458605449 3.021202295 1.922064963 1 7.550562043 -9.203602726 0.726405066 0.894838476 2.4437741 0.392992168 0.431531223 0.345350601 0.294724763 0.323265103 0.070693029 6.26E-10 9.203602726 1.548935625 GVS(ph)MPNMLEPK ddPTM_HeLa_Curcumin_4h_R1 2 GVSMPNMLEPK 11 0 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 GVS(1)MPNMLEPK;GVS(1)MPNMLEPK ; 156.52 0.00041495 149605000 6195.1 5211.8 5933.3 5763.2 5146.1 7349.2 6632.4 7630 6490.9 6704.7 TRUE FALSE FALSE 5704.751298 5662.284769 6153.193317 5739.353405 5084.736119 5824.893077 6818.487294 9956.351876 5778.864509 6937.687826 0.822284231 0.816163095 0.886922772 0.827271787 0.732915093 0.839601496 0.982818406 1.435110966 0.832966927 1 12.76023921 -4.274058933 3.047083944 0.881981484 1.514804463 0.854294189 0.071889144 0.130426895 1.818447349 0.013179613 0.195631165 5.32E-05 4.274058933 0.632822979 GVS(ph)QEKEAQISSAIVSSVQSK ddPTM_HeLa_Curcumin_4h_R1 2 GVSQEKEAQISSAIVSSVQSK 21 1 Q12872-2;Q12872 Q12872-2 SFSWAP "Splicing factor, suppressor of white-apricot homolog" 1 0 GVS(1)QEKEAQISSAIVSSVQSK;GVS(0.92)QEKEAQIS(0.052)S(0.017)AIVS(0.01)S(0.001)VQSK ; 99.378 8.20E-05 109019000 6405.3 4960.3 5107.8 5752.5 5085.3 6468.6 5141.7 2874.9 5669.5 5309.9 TRUE FALSE FALSE 5898.313746 5389.046229 5297.099561 5728.697679 5024.661119 5126.939444 5285.962264 3751.443776 5047.570034 5494.41863 1.073510073 0.98082192 0.964087362 1.042639461 0.914502781 0.933117731 0.962060342 0.682773561 0.91867227 1 12.42375112 -3.410380136 0.678291526 1.025084873 3.31E-26 0.640148542 0.060432816 2.958304159 0.412549251 0.008927718 3.066002646 0.000388705 3.410380136 -1.025084873 GVS(ph)SESSGDREK ddPTM_HeLa_Curcumin_4h_R1 2 GVSSESSGDREK 12 1 E9PPJ0;Q13435;H0YCG1;E9PJ04 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 0 GVS(0.969)S(0.031)ESSGDREK;GVS(0.848)S(0.151)ESSGDREK ; 96.135 0.0050104 62880000 5277.3 5382.8 4835 4973 6202 7284.5 6156.6 8577.4 6062.1 6601.8 TRUE FALSE FALSE 4859.596136 5848.065247 5014.189353 4952.423044 6128.045201 5773.612587 6329.337626 11192.60977 5397.102797 6831.212059 0.711381245 0.85608018 0.734011667 0.724969888 0.897065579 0.845181285 0.926532154 1.638451519 0.790065182 1 12.73792586 -4.2544763 3.482342786 0.843237765 1.742406626 0.888961114 0.085948566 0.09908845 2.036556814 0.016317199 0.235928896 5.57E-05 4.2544763 0.899168861 GVSAVAGPHDIGAS(ph)PGDKK ddPTM_HeLa_Curcumin_4h_R1 1 GVSAVAGPHDIGASPGDKK 19 1 C9JGP4;Q8IYB7-4;Q8IYB7-5;Q8IYB7-3;Q8IYB7-2;Q8IYB7 C9JGP4 DIS3L2 DIS3-like exonuclease 2 1 0 GVSAVAGPHDIGAS(1)PGDKK 158.52 1.15E-05 49892000 1573.2 1603.9 1384.6 1363.9 1569.5 2330.4 1906.5 524.75 1458.3 1337.5 TRUE FALSE FALSE 1448.67956 1742.533969 1435.914494 1358.256543 1550.784738 1847.048771 1959.991259 684.7438593 1298.328138 1383.978025 1.046750406 1.259076327 1.037526946 0.981414819 1.120526995 1.334594002 1.416201141 0.494764979 0.938113261 1 10.43460532 -7.49811083 15.89744601 1.020619436 1.111728479 0.026715385 0.239692586 13.26264541 8515.194582 0.03911452 0.04250563 3.18E-08 7.49811083 0.091109043 GPEDSWLLLSAPGPT(ph)PASPRPASPCGK ddPTM_HeLa_Curcumin_4h_R1 1 GPEDSWLLLSAPGPTPASPRPASPCGK 27 1 Q14934-2;Q14934-9;Q14934-3;Q14934-4;Q14934-5;Q14934-6;Q14934-7;Q14934;Q14934-8;Q14934-10;Q14934-18;Q14934-11;Q14934-12;Q14934-13;Q14934-14;Q14934-15;Q14934-16;Q14934-17 Q14934-2 NFATC4 "Nuclear factor of activated T-cells, cytoplasmic 4" 1 0 GPEDSWLLLSAPGPT(0.857)PAS(0.037)PRPAS(0.105)PCGK 117.04 5.88E-09 17584000 1728.9 1351.1 1513.3 1384.9 1614.8 1864.9 948.92 382.91 1579.1 1233.6 TRUE FALSE FALSE 1592.055741 1467.883064 1569.384229 1379.169651 1595.544565 1478.098718 975.5441413 499.6574963 1405.876681 1276.467508 1.247235617 1.149957249 1.229474483 1.080458094 1.249968804 1.157960315 0.764253015 0.391437693 1.101380702 1 10.3179411 -4.497972959 2.46048359 1.139247147 0.374199985 0.90546651 0.078540729 0.098877628 0.998478204 0.014918057 0.12669001 3.18E-05 4.497972959 -0.765047163 down SMS(ph)ENAVR ddPTM_HeLa_Curcumin_4h_R1 2 SMSENAVR 8 0 Q9GZY8-5;C9JHF5;A0A0A0MS29;Q9GZY8-4;Q9GZY8-3;Q9GZY8-2;Q9GZY8;H7C433 Q9GZY8-5 MFF Mitochondrial fission factor 1 0 S(0.028)MS(0.972)ENAVR;S(0.094)MS(0.906)ENAVR ; 110.84 0.0085531 401283000 8086.8 6997.1 6640.2 7888.7 8741.1 12624 5420.4 2197.41 10045.3 7647 TRUE FALSE FALSE 7446.721247 7601.898146 6886.291653 7856.05865 8636.868091 10005.6401 5572.481836 2867.390193 8943.355722 7912.732681 0.941106132 0.96071717 0.87027983 0.992837616 1.091515212 1.264498689 0.704242398 0.36237673 1.130248687 1 12.9499603 -4.4979518 4.466142226 0.989782683 0.414394857 0.77113794 0.113681957 0.067050781 3.152189693 0.014892075 0.080748837 3.18E-05 4.4979518 -0.575387826 down GVSNESVPDS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 1 GVSNESVPDSPAR 13 0 Q86XJ1;G3V1N3 Q86XJ1 GAS2L3 GAS2-like protein 3 1 0 GVSNES(0.001)VPDS(0.999)PAR 106.76 0.0053793 0 1426.3 1246.1 1296.1 1347.8 1715.5 2217.1 1862.1 905.37 1588.6 1322.9 TRUE FALSE FALSE 1313.40685 1353.807331 1344.134606 1342.223161 1695.043783 1757.248468 1914.345514 1181.413145 1414.334554 1368.870677 0.959482055 0.988995787 0.981929578 0.980533212 1.238278978 1.283721317 1.398485297 0.8630568 1.03321269 1 10.41877044 -5.76458272 24.72525306 0.981166195 1.216631008 0.372159166 0.129093569 45.82599137 360468.7123 0.017113661 0.031997064 1.72E-06 5.76458272 0.235464814 GVSS(ph)PVETR ddPTM_HeLa_Curcumin_4h_R1 1 GVSSPVETR 9 0 A8MVZ6;Q96G01-4;Q96G01-3;Q96G01 A8MVZ6 BICD1 Protein bicaudal D homolog 1 1 0 GVS(0.131)S(0.869)PVETR 106.2 0.010378 25090000 2048.3 1805.1 1746.1 1734.7 1462.7 2327.5 1413.8 1219.6 2209.9 1999.5 TRUE FALSE FALSE 1886.174894 1961.124801 1810.812002 1727.522271 1445.258258 1844.750264 1453.467423 1591.450426 1967.479499 2068.982476 0.911643726 0.947869217 0.875218627 0.834962254 0.698535766 0.891621986 0.702503496 0.769194734 0.95094063 1 11.01470571 -6.275871413 0.351935102 0.99451777 0.704282216 0.668701013 0.057330049 0.720741118 0.174729978 0.027356367 0.080309415 5.30E-07 6.275871413 -0.290235553 GVSSESSGDREK(ac)DSTR ddPTM_HeLa_Curcumin_4h_R1 1 GVSSESSGDREKDSTR 16 2 E9PPJ0;Q13435;H0YCG1 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 0 1 GVSSESSGDREK(1)DSTR 67.326 0.01076 606290 182.44 135.03 169.15 161.29 94.499 413.32 189.98 139.41 290.79 276.59 FALSE TRUE FALSE 167.9996815 146.7013915 175.4188478 160.6226247 93.37216114 327.5927729 195.3103275 181.9154672 258.8910645 286.2014819 0.586997944 0.512580824 0.612920823 0.561222198 0.326246253 1.144622909 0.682422488 0.635620284 0.904576254 1 8.160887332 -9.213003076 0.93712812 1.001393766 0.633777955 0.29143466 0.197108618 0.538020512 0.844561226 0.13333924 0.036735401 6.12E-10 9.213003076 -0.367615811 GVTFNVTTVDTK ddPTM_HeLa_Curcumin_4h_R1 2 GVTFNVTTVDTK 12 0 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 0 0 ; ; 187.58 4.25E-10 4077100 2017.63 1870.79 2084.41 1883.37 2001.93 2691.9 2320.5 2369.76 2399.4 1872.9 FALSE FALSE TRUE 1857.932457 2032.492752 2161.660068 1875.577114 1978.058292 2133.569596 2385.606985 3092.288915 2136.191823 1937.983136 0.958693821 1.048766996 1.115417378 0.96779847 1.020678795 1.100922684 1.230974068 1.5956222 1.102275755 1 10.9203403 -2.323555478 0.747565615 0.99156456 12.55305734 0.898079262 0.056877491 6.663037377 0.235186973 0.0078863 116.3977887 0.004747276 2.323555478 11.56149278 GVTIPYRPKPSSS(ph)PVIFAGGQDR ddPTM_HeLa_Curcumin_4h_R1 1 GVTIPYRPKPSSSPVIFAGGQDR 23 2 Q15366;Q15366-2;Q15366-3;Q15366-6;H3BSS4 Q15366 PCBP2 Poly(rC)-binding protein 2 1 0 GVTIPY(0.001)RPKPS(0.009)S(0.198)S(0.793)PVIFAGGQDR 83.251 0.00031661 813750000 1561.2 1652.3 1822.9 1817.1 1605.8 1880.5 1654.8 781.42 1749.9 2083.5 TRUE FALSE FALSE 1437.629373 1795.117449 1890.458278 1809.581322 1586.651884 1490.463102 1701.229234 1019.671361 1557.940348 2155.90147 0.666834451 0.832652825 0.876876009 0.839361792 0.735957513 0.691341011 0.789103425 0.472967515 0.722639865 1 11.07407553 -13.5228787 0.291488969 3.174789641 0.717770574 0 0.139435923 32.89877301 0.445070565 41.87911317 0.048696876 3.00E-14 13.5228787 -2.457019067 GVTMVS(ph)PSTAGGPAQK ddPTM_HeLa_Curcumin_4h_R1 1 GVTMVSPSTAGGPAQK 16 0 Q7Z6J0 Q7Z6J0 SH3RF1 E3 ubiquitin-protein ligase SH3RF1 1 0 GVT(0.228)MVS(0.662)PS(0.096)T(0.015)AGGPAQK 120.21 0.0010801 3201700 1766.8 1832.1 1761 1677.2 1926.1 2669.2 2648.6 2259.9 1739.8 1453.2 TRUE FALSE FALSE 1626.955916 1990.45856 1826.264209 1670.260191 1903.132515 2115.577832 2722.912588 2948.933107 1548.948293 1503.698592 1.081969435 1.323708469 1.21451481 1.110767942 1.265634301 1.406916149 1.810810093 1.961119817 1.030092268 1 10.5542997 -1 0.355490158 1.027515647 13.53003154 0.908254142 0.093871315 10.59369244 0.132060015 0.027770298 90.40895458 0.1 1 12.50251589 GVTQFGNK(ac)YIQQTK ddPTM_HeLa_Curcumin_4h_R1 2 GVTQFGNKYIQQTK 14 1 O43809 O43809 NUDT21 Cleavage and polyadenylation specificity factor subunit 5 0 1 ; GVTQFGNK(1)YIQQTK;GVTQFGNK(1)YIQQTK 338.77 1.55E-203 7608400 1556.92 1811.03 1728.78 1876.13 1695.7 2857.4 2337.9 1339.55 2000.4 1739.53 FALSE TRUE FALSE 1433.688139 1967.567363 1792.850108 1868.367071 1675.479885 2264.74303 2403.495182 1747.972628 1780.961125 1799.978538 0.796502908 1.093106013 0.996039714 1.037994083 0.930833257 1.258205574 1.335291022 0.971107484 0.989434644 1 10.81376399 -5.753087002 0.906620474 0.916728446 1.195057754 0.251810171 0.12820132 0.487402618 0.75047934 0.023547776 0.079969344 1.77E-06 5.753087002 0.278329308 GVTQFGNK(ac)YIQQTKPLTLER ddPTM_HeLa_Curcumin_4h_R1 1 GVTQFGNKYIQQTKPLTLER 20 2 O43809 O43809 NUDT21 Cleavage and polyadenylation specificity factor subunit 5 0 1 GVTQFGNK(1)YIQQTKPLTLER 225.69 4.44E-29 12937000 2099.5 2100.1 1817.1 1742.2 1460.7 4741.1 2928.3 2574.1 2429.6 2197 FALSE TRUE FALSE 1933.32236 2281.623286 1884.443324 1734.991238 1443.282107 3757.742417 3010.460217 3358.93124 2163.078959 2273.345586 0.850430472 1.003641197 0.828929546 0.763188513 0.634871405 1.652956963 1.324242225 1.477527772 0.95149588 1 11.1506013 -5.256735304 24.9997041 0.896065378 1.468842324 0.823526074 0.131452955 133.0677159 707181.7975 0.019474122 0.047923145 5.54E-06 5.256735304 0.572776946 GVVDSDDLPLNVSR ddPTM_HeLa_Curcumin_4h_R1 2 GVVDSDDLPLNVSR 14 0 P14625 P14625 HSP90B1 Endoplasmin 0 0 ; ; 299.42 1.09E-90 53580000 5618.2 4596.8 5664.1 4910.7 4845.5 6726.2 5109.1 3429.1 5737.7 5394 FALSE FALSE TRUE 5173.513542 4994.126909 5874.016529 4890.380825 4787.720577 5331.1103 5252.447596 4474.616804 5108.288665 5581.441099 0.926913578 0.894773737 1.052419335 0.876186049 0.857792906 0.955149433 0.941055814 0.801695606 0.915227551 1 12.44642195 -1.000066004 0.017719694 1.665337711 1.01E-05 0.127744643 0.063385265 3292.557469 4.546398218 164.5293154 276.4753609 0.099984803 1.000066004 -1.665327604 GVVDSEDLPLNISR ddPTM_HeLa_Curcumin_4h_R1 5 GVVDSEDLPLNISR 14 0 P08238;P07900;P07900-2 P08238;P07900 HSP90AB1;HSP90AA1 Heat shock protein HSP 90-beta;Heat shock protein HSP 90-alpha 0 0 ;;;; ;;;; 282.05 2.02E-62 164408000 17458.1 14847.5 14682.3 16068.9 15137.7 17710.2 15414.4 15221.5 17398.8 15881.5 FALSE FALSE TRUE 16076.27296 16130.85174 15226.43895 16002.41115 14957.19281 14036.90488 15846.88658 19862.46528 15490.19517 16433.38094 0.978269354 0.981590568 0.926555467 0.973774734 0.910171368 0.854170236 0.964310791 1.208665785 0.942605494 1 14.00434171 -8.004589036 1.003019973 0.995422828 0.965550986 0 0.0890292 1.872254 3.993011191 0.024069997 0.019091926 9.89E-09 8.004589036 -0.029871842 GVVEVTHDLQK ddPTM_HeLa_Curcumin_4h_R1 2 GVVEVTHDLQK 11 0 P50454;E9PKH2 P50454 SERPINH1 Serpin H1 0 0 ; ; 136.02 0.00011134 11833200 11983.9 9800 11635.3 11317.5 10100.6 11246.1 8475.3 6430.1 11520.1 12025.6 FALSE FALSE TRUE 11035.36167 10647.06833 12066.51445 11270.67118 9980.156942 8913.53209 8713.094108 8390.607889 10256.37385 12443.4887 0.886838244 0.855633704 0.9697051 0.905748496 0.802038494 0.716320985 0.700213125 0.674297063 0.824236201 1 13.6031034 -2.774966419 0.240791896 0.984764825 8.55E-17 0.636779048 0.063993615 6.494370569 0.167979281 0.033821279 2.161748766 0.001678934 2.774966419 -0.984764825 QGLAETASPVAVS(ph)LR ddPTM_HeLa_Curcumin_4h_R1 2 QGLAETASPVAVSLR 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 0 QGLAET(0.007)AS(0.002)PVAVS(0.991)LR;QGLAET(0.013)AS(0.405)PVAVS(0.583)LR ; 137.27 0.00058694 33866000 3534.6 2755.5 2911.5 2950.3 2771.9 2945.5 1599.84 526.26 3433.5 2808.6 TRUE FALSE FALSE 3254.83268 2993.673142 3019.402751 2938.09244 2738.846903 2334.570097 1644.727205 686.7142514 3056.85364 2906.198641 1.11996222 1.030099285 1.03895264 1.010974404 0.942415589 0.803307133 0.565937642 0.23629295 1.051839195 1 11.5049176 -4.493393315 0.952704725 1.054212294 7.83E-18 0.986160361 0.030884822 0.163903649 0.142893734 0.007185986 0.162586707 3.21E-05 4.493393315 -1.054212294 down GVVIPTWNIS(ph)PIKK ddPTM_HeLa_Curcumin_4h_R1 1 GVVIPTWNISPIKK 14 1 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9;A4PB68 A0A087WUE6 GON4L GON-4-like protein 1 0 GVVIPTWNIS(1)PIKK 94.569 0.0036007 22921000 5286.9 4640.3 4564.8 4758.9 4626 5603.6 4691.8 2041.1 5530.2 4631.2 TRUE FALSE FALSE 4868.436286 5041.386855 4733.975504 4739.208933 4570.837971 4441.350194 4823.439281 2663.421994 4923.550896 4792.133855 1.015922433 1.052012946 0.987863788 0.988955876 0.953821014 0.926800112 1.006532669 0.5557904 1.027423491 1 12.22645249 -4.260854112 24.99830048 0.99906695 0.555790265 0.938240848 0.033831234 8.277381447 353462.1557 0.004855254 0.038604501 5.48E-05 4.260854112 -0.443276685 GVVPLAGTDGETTTQGLDGLSER ddPTM_HeLa_Curcumin_4h_R1 2 GVVPLAGTDGETTTQGLDGLSER 23 0 P09972;K7EKH5;C9J8F3;J3KSV6;J3QKP5;A8MVZ9 P09972 ALDOC Fructose-bisphosphate aldolase C;Fructose-bisphosphate aldolase 0 0 ; ; 233.28 4.33E-29 31061000 7059.4 6575 6428.1 6924.1 6508.8 8223.3 6544.4 6687.5 7535.8 6135.2 FALSE FALSE TRUE 6500.641041 7143.313702 6666.331041 6895.449909 6431.186811 6517.694884 6728.018251 8726.487965 6709.141594 6348.397743 1.023981374 1.12521521 1.050080872 1.08617169 1.013040939 1.026667696 1.059797845 1.374596917 1.056824393 1 12.6321768 -4.258309972 3.845490722 1.02899544 1.409808168 0.861627832 0.038576985 0.068561468 1.974778121 0.005888646 0.073640676 5.52E-05 4.258309972 0.380812728 GVVPLAGTNGETTTQGLDGLSER ddPTM_HeLa_Curcumin_4h_R1 2 GVVPLAGTNGETTTQGLDGLSER 23 0 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7;H3BR04;H3BMQ8;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 ; ; 245.18 2.82E-51 7398400 1057.7 1079.47 1339.3 1132.73 1454.36 1204.8 1012.5 1005.4 1246.72 1118.477 FALSE FALSE TRUE 973.9819289 1172.774577 1388.935636 1128.043063 1437.017707 954.9108991 1040.908025 1311.941832 1109.957935 1157.343992 0.841566496 1.013332755 1.200106144 0.97468261 1.241651329 0.825088224 0.899393812 1.133579852 0.959056203 1 10.17660202 -7.021256362 23.83418056 0.9253034 1.040740015 0.13519374 0.12607969 613.1776046 687538.5649 0.021534335 0.026531909 9.52E-08 7.021256362 0.115436614 GVVQELQQAISK ddPTM_HeLa_Curcumin_4h_R1 1 GVVQELQQAISK 12 0 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;E9PL12;E9PPR1;E9PIZ1;E9PMW7;E9PN91;H0YCK7 P29692;E9PMW7 EEF1D Elongation factor 1-delta 0 0 197.07 4.43E-57 0 627.31 715.97 754.68 530.64 599.27 972.92 559.31 559.07 776.59 550.95 FALSE FALSE TRUE 577.6577516 777.8552565 782.6491047 528.4443523 592.1240966 771.1254249 575.0027333 729.5278694 691.4000199 570.0954715 1.013264936 1.364429811 1.372838663 0.926940098 1.038640239 1.352625066 1.008607789 1.27965912 1.212779358 1 9.155059731 -7.4681171 24.80145029 1.005852084 1.182448977 0.048126925 0.163344609 297.4924184 134734.4709 0.025174834 0.028771304 3.40E-08 7.4681171 0.176596893 GVVQLFNAVQK(ac)HQK ddPTM_HeLa_Curcumin_4h_R1 1 GVVQLFNAVQKHQK 14 1 Q9Y3B9 Q9Y3B9 RRP15 RRP15-like protein 0 1 GVVQLFNAVQK(1)HQK 150.49 0.0012605 1628100 711.86 673.46 660.23 537 382.43 1052.1 659.25 442.51 604.42 699.02 FALSE TRUE FALSE 655.5155298 731.6708815 684.6987046 534.7780363 377.869772 833.8826004 677.7467807 577.4292619 538.1166382 723.310893 0.906270784 1.011557946 0.946617438 0.739347411 0.522416814 1.152868854 0.937006185 0.798314069 0.743963133 1 9.498472068 -6.417534369 8.975858284 0.95964303 0.836927707 0.047832532 0.16536609 0.569007293 44.67398222 0.02355909 0.03599711 3.82E-07 6.417534369 -0.122715324 GVVVVIK ddPTM_HeLa_Curcumin_4h_R1 2 GVVVVIK 7 0 H0YMF4;H0YKD8;P46779-4;P46779-5;P46779;P46779-2;P46779-3 H0YMF4 RPL28 60S ribosomal protein L28 0 0 ; ; 110.24 0.01374 38995000 11871.7 10434.1 9737.9 10337.7 9717.2 11873.2 9170.7 9106.8 10869.3 9886.7 FALSE FALSE TRUE 10932.04242 11335.97711 10098.79514 10294.92534 9601.328737 9410.564481 9428.00516 11883.4214 9676.964984 10230.26209 1.06859847 1.108082766 0.98714921 1.006320781 0.938522264 0.919875209 0.921580022 1.16159501 0.945915647 1 13.32055549 -6.55967727 24.97568857 1.039386988 0.980856303 0.055924865 0.076288996 255.9114219 173689.7862 0.011125053 0.015733216 2.76E-07 6.55967727 -0.058530685 GVVVVIKR ddPTM_HeLa_Curcumin_4h_R1 1 GVVVVIKR 8 1 H0YMF4;H0YKD8;P46779-4;P46779-5;P46779;P46779-2;P46779-3 H0YMF4 RPL28 60S ribosomal protein L28 0 0 118.69 2.68E-05 0 3042.5 2539.7 2604.8 2922.7 2359.3 4428.7 3259 4158 4693.5 5132 FALSE FALSE TRUE 2801.682915 2759.220351 2701.336179 2910.606642 2331.166888 3510.137698 3350.438769 5425.755059 4178.634793 5310.336618 0.527590455 0.519594246 0.508693963 0.548102098 0.438986651 0.661000978 0.630927757 1.021734675 0.786886989 1 12.3745876 -9.258140806 0.954067112 1.003589887 0.59363193 0.293739243 0.16483638 0.381836618 0.61519711 0.108160499 0.028567884 5.52E-10 9.258140806 -0.409957957 GWAFGSNS(ph)LPIAGSVGMGVAR ddPTM_HeLa_Curcumin_4h_R1 3 GWAFGSNSLPIAGSVGMGVAR 21 0 A0A087WZT0;M0QZ22;Q5PRF9 A0A087WZT0 SAMD4B Protein Smaug homolog 2 1 0 GWAFGS(0.035)NS(0.516)LPIAGS(0.45)VGMGVAR;GWAFGS(0.093)NS(0.907)LPIAGSVGMGVAR;GWAFGS(0.004)NS(0.995)LPIAGSVGMGVAR ;; 150.69 1.78E-10 10883000 4674.9 3766.69 4084.1 4165.4 3949.11 6440.8 3989.42 2617.06 5114.65 4430.12 TRUE FALSE FALSE 4304.876732 4092.2659 4235.460339 4148.164678 3902.019442 5104.905477 4101.352388 3414.989547 4553.585691 4584.06634 0.939095644 0.892715244 0.923952671 0.904909391 0.851213563 1.113619459 0.894697433 0.744969486 0.99335074 1 12.16241221 -4.885050235 0.016698492 1.796348496 8.31E-07 0.189579464 0.083623053 2077.526147 6.810599181 332.483871 402.4088483 1.30E-05 4.885050235 -1.796347665 GWAFGSNSLPIAGS(ph)VGMGVAR ddPTM_HeLa_Curcumin_4h_R1 1 GWAFGSNSLPIAGSVGMGVAR 21 0 A0A087WZT0;M0QZ22;Q5PRF9 A0A087WZT0 SAMD4B Protein Smaug homolog 2 1 0 GWAFGS(0.002)NS(0.126)LPIAGS(0.873)VGMGVAR 66.708 0.0046241 11027000 837.61 592.88 796.57 665.03 630.89 1285.3 685.41 398.12 803.3 954.08 TRUE FALSE FALSE 771.3122847 644.1259054 826.0915849 662.2782821 623.3670488 1018.714292 704.6407599 519.5049553 715.1799998 987.234209 0.781286019 0.65245501 0.836773663 0.670842112 0.631427723 1.031887147 0.713752374 0.526222603 0.724427895 1 9.947248576 -8.835215763 0.553818114 1.022142514 0.726919562 0 0.153936765 0.831854786 0.45188818 0.12142001 0.033338418 1.46E-09 8.835215763 -0.295222952 GWAWDGK(ac)SVVNDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 GWAWDGKSVVNDKK 14 2 P47869 P47869 GABRA2 Gamma-aminobutyric acid receptor subunit alpha-2 0 2 GWAWDGK(1)SVVNDK(1)K 70.622 0.0085645 7166200 1423.4 1503.7 882.13 1338.8 1602.5 4129 2278.2 2138.1 4769.8 1566 FALSE TRUE FALSE 1310.736388 1633.673128 914.8225138 1333.2604 1583.391234 3272.598857 2342.120161 2789.996847 4246.564873 1620.418383 0.808887631 1.008179828 0.564559452 0.822787753 0.977149636 2.019601166 1.4453799 1.721775608 2.620659526 1 10.66215064 -5.352819695 6.187603803 0.883169483 1.697735264 0.111800878 0.577139477 0.067898037 3.777370736 0.024953825 0.056410366 4.44E-06 5.352819695 0.814565781 GWDAEGS(ph)PFR ddPTM_HeLa_Curcumin_4h_R1 3 GWDAEGSPFR 10 0 Q8IVD9 Q8IVD9 NUDCD3 NudC domain-containing protein 3 1 0 GWDAEGS(1)PFR;GWDAEGS(1)PFR;GWDAEGS(1)PFR ;; 119.34 0.0046816 11693800 8953.1 8090.8 8441.9 9850.7 9678.2 14895 13413.4 6573.5 8474.6 7106 TRUE FALSE FALSE 8244.452688 8790.1327 8754.76424 9809.940413 9562.793786 11805.6091 13789.7439 8577.729889 7544.957582 7352.932971 1.121246817 1.195459381 1.190649265 1.334153385 1.300541406 1.605564629 1.875407264 1.166572567 1.026115376 1 12.84410412 -6.106757245 0.677830472 1.044966222 1.587529038 0.53959015 0.174304082 0.387728342 0.336734809 0.034513413 0.101826549 7.82E-07 6.106757245 0.542562816 GWDS(ph)SHEDDLPVYLAR ddPTM_HeLa_Curcumin_4h_R1 1 GWDSSHEDDLPVYLAR 16 0 Q14195-2 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 1 0 GWDS(0.802)S(0.198)HEDDLPVYLAR 104.16 0.00097783 5475700 4351.6 4066.3 4671.2 4029.7 5287.4 4811.5 3718.1 3255.5 4099.2 3902.3 TRUE FALSE FALSE 4007.166268 4417.772853 4844.318781 4013.026169 5224.351208 3813.540663 3822.419879 4248.086964 3649.528016 4037.904635 0.992387545 1.094075579 1.199711043 0.993838768 1.293827289 0.944435545 0.946634511 1.052052326 0.903817288 1 11.97939112 -7.268557176 23.49886439 0.996405226 1.075083552 0.164847823 0.106321368 399.7663822 1319797.205 0.017025854 0.019711242 5.39E-08 7.268557176 0.078678326 GWDSS(ph)HEDDLPVYLAR ddPTM_HeLa_Curcumin_4h_R1 2 GWDSSHEDDLPVYLAR 16 0 Q14195-2 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 1 0 GWDS(0.464)S(0.536)HEDDLPVYLAR;GWDS(0.41)S(0.59)HEDDLPVYLAR ; 134.08 0.00020681 8652700 5034 4652.7 5543.6 4921.7 5930.3 5209.4 3603.5 2786.88 4174.6 3696.1 TRUE FALSE FALSE 4635.553588 5054.858656 5749.050693 4901.335309 5859.585046 4128.911718 3704.604512 3636.586883 3716.656824 3824.5392 1.212055452 1.3216909 1.50320088 1.281549241 1.532102232 1.079584102 0.968640748 0.950856219 0.971792059 1 11.90107022 -2.97432081 13.73189585 1.162763534 1.166049799 0 0.211323345 0 0 0.029889003 0 0.001060912 2.97432081 0.003286265 GWDSSHEDDLPVYLAR ddPTM_HeLa_Curcumin_4h_R1 1 GWDSSHEDDLPVYLAR 16 0 Q14195-2 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 0 0 199.38 4.29E-08 4532200 1731.4 1901.1 1663 1503.1 2684.9 2915.2 2016.1 2018.6 1830.1 1590.2 FALSE FALSE TRUE 1594.357863 2065.422613 1724.632243 1496.88057 2652.884321 2310.554659 2072.66634 2634.061848 1629.342609 1645.459332 0.968943949 1.255225561 1.048115994 0.909703778 1.61224545 1.404200404 1.259627813 1.600806411 0.990205335 1 10.68427465 -5.766538747 24.99999993 1.007988916 1.449604905 0.740505695 0.127187911 46.38175825 227391.1377 0.018435177 0.034166932 1.71E-06 5.766538747 0.44161599 SQSLPHSAT(ph)VTLGGTSDPSTLSSSALSER ddPTM_HeLa_Curcumin_4h_R1 1 SQSLPHSATVTLGGTSDPSTLSSSALSER 29 0 F8WDP1;A0A0A0MRY0;Q8WUA7-3;Q8WUA7-4;Q8WUA7 F8WDP1 TBC1D22A TBC1 domain family member 22A 1 0 S(0.001)QS(0.005)LPHS(0.226)AT(0.602)VT(0.161)LGGT(0.004)S(0.002)DPSTLSSSALSER 77.03 4.13E-05 6517900 1544.8 940.51 1468.2 1538.4 1434.9 2156.7 1665.4 6276.6 1643.5 1426.1 TRUE FALSE FALSE 1422.52745 1021.803494 1522.612784 1532.034508 1417.789755 1709.376109 1712.126642 8190.306446 1463.212162 1475.656869 0.963996089 0.692439764 1.031820348 1.038205114 0.960785522 1.158383189 1.160247127 5.550278401 0.991566666 1 10.52714158 -4.260326567 5.174799921 0.982261916 5.756158288 0.993503983 0.110473761 0.008756877 0.780524823 0.015688184 0.148317775 5.49E-05 4.260326567 4.773896372 up GWLRDPSAS(ph)PGDAGEQAIR ddPTM_HeLa_Curcumin_4h_R1 1 GWLRDPSASPGDAGEQAIR 19 1 P18206;P18206-2 P18206 VCL Vinculin 1 0 GWLRDPS(0.046)AS(0.954)PGDAGEQAIR 100.14 0.00043715 12713000 1199.6 906.02 1308.6 870.03 1439.9 1615.4 1168.9 1338.1 950.8 724.3 TRUE FALSE FALSE 1104.650394 984.3323317 1357.097867 866.4300464 1422.730133 1280.347831 1201.696188 1746.08053 846.4996188 749.4693711 1.473909991 1.313372327 1.810744934 1.156057979 1.898316579 1.7083391 1.603395995 2.329755688 1.129465261 1 9.54972571 -1 0.084999857 0.509846379 4.563118339 0.618959451 0.240740163 74.71996465 0.463864818 3.188363001 35.59043747 0.1 1 4.05327196 GWQDVTATSAYK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 GWQDVTATSAYKK 13 1 H0YC42;P55327-2;P55327;P55327-3;P55327-4;P55327-7;P55327-5;P55327-6 H0YC42 TPD52 Tumor protein D52 0 1 GWQDVTATSAYK(1)K 180.18 3.01E-44 0 135.16 212.91 132.41 169.09 256.84 427.06 258.37 276.84 294.13 295.84 FALSE TRUE FALSE 124.4619434 231.3129917 137.3172311 168.3903504 253.7773507 338.482942 265.6191668 361.2472416 261.8646749 306.120418 0.406578379 0.755627453 0.448572598 0.550078794 0.829011513 1.10571828 0.867695035 1.180082152 0.85543028 1 8.257955464 -5.478797102 4.586999896 0.682834522 1.028595812 0.45931112 0.184435844 0.208946746 9.788127121 0.035481994 0.07948084 3.32E-06 5.478797102 0.34576129 VDTNAPDLS(ph)LEGPEGK ddPTM_HeLa_Curcumin_4h_R1 2 VDTNAPDLSLEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VDT(0.001)NAPDLS(0.999)LEGPEGK;VDTNAPDLS(1)LEGPEGK ; 140.32 0.00039496 16858300 2965.1 2261 2226.8 2819 2836.5 3559.6 2872.2 5383 3119.2 2779.1 TRUE FALSE FALSE 2730.409206 2456.430765 2309.327167 2807.335725 2802.67659 2821.298835 2952.786202 7024.25192 2777.031564 2875.673518 0.949485117 0.854210587 0.803056102 0.9762359 0.974615711 0.981091496 1.026815521 2.442645827 0.965697791 1 11.48968418 -4.260307307 4.890465448 0.956039392 2.522097505 0.981852197 0.061030597 0.017730742 1.25254967 0.009554327 0.09392402 5.49E-05 4.260307307 1.566058113 up GYADS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 3 GYADSPSK 8 0 Q01518-2;Q01518;Q5T0R7;Q5T0R6;Q5T0R5;Q5T0R4;Q5T0R3;Q5T0R2;Q5T0R1;Q5T0R9;Q5T0R8;Q5T0S3 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1;Adenylyl cyclase-associated protein 1 0 GYADS(0.988)PS(0.012)K;GYADS(0.993)PS(0.007)K;GYADS(0.964)PS(0.036)K ;; 114.51 0.0099767 1141100000 23035 32513.1 25500.7 20527.3 23514.8 27006.8 18244.8 7880.6 18564.5 20735.2 TRUE FALSE FALSE 21211.75544 35323.38749 26445.77837 20442.36347 23234.40137 21405.28525 18756.69998 10283.35866 16528.0208 21455.74666 0.988628165 1.646336902 1.232573203 0.952768682 1.082898756 0.997648117 0.87420402 0.479282256 0.770330721 1 14.38907649 -4.083000663 1.344182133 1.065316454 0.023774511 0.419383019 0.218296716 1.504630407 1.7363796 0.031330772 2.379673738 8.26E-05 4.083000663 -1.041541943 GYAFIEYEHER ddPTM_HeLa_Curcumin_4h_R1 2 GYAFIEYEHER 11 0 P08621;P08621-2;M0QYR1;P08621-3 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 0 0 ; ; 178.46 0.0001397 79024000 11695.6 8333.7 8950.5 8651.5 9879.3 12340.8 9966.7 9275.1 10422.6 8961.9 FALSE FALSE TRUE 10769.88092 9054.027894 9282.213404 8615.702385 9761.4958 9781.178971 10246.33878 12103.03529 9279.266856 9273.325358 1.161382838 0.976351799 1.000958453 0.92908445 1.052642437 1.054764995 1.104926052 1.305145115 1.000640708 1 13.17887106 -4.236396379 2.316074257 1.051816988 1.377297451 0.620417803 0.063789645 0.441911661 2.619997046 0.011322668 0.296934688 5.80E-05 4.236396379 0.325480463 GYAFNHSADFETVR ddPTM_HeLa_Curcumin_4h_R1 1 GYAFNHSADFETVR 14 0 P61160;F5H6T1;P61160-2 P61160 ACTR2 Actin-related protein 2 0 0 77.633 0.017315 7766500 3143.8 2076 2414 2668.1 2584.6 3535.6 3129 2499.5 2904.5 2599.4 FALSE FALSE TRUE 2894.964913 2255.44019 2503.464964 2657.060109 2553.780333 2802.276706 3216.791319 3261.586044 2585.883617 2689.728957 1.076303583 0.838538093 0.930749902 0.987854223 0.949456386 1.041843528 1.195953708 1.2126077 0.961391894 1 11.39324508 -4.794946055 3.783042077 1.004542916 1.210389742 0.64501541 0.065927611 0.125235094 3.734997803 0.010690302 0.039346908 1.60E-05 4.794946055 0.205846825 GYALVPIIVNSST(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 GYALVPIIVNSSTPK 15 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 0 GYALVPIIVNS(0.062)S(0.211)T(0.728)PK 93.243 0.018199 24305000 1494.1 1535.3 1495.1 1328 1565.8 2416.9 1797.4 821.3 2031.8 1276.1 TRUE FALSE FALSE 1375.840408 1668.004491 1550.509721 1322.505088 1547.128858 1915.607696 1847.830207 1071.710589 1808.916623 1320.44438 1.041952565 1.263214503 1.174233269 1.001560617 1.171672871 1.450729561 1.399400258 0.811628725 1.369930192 1 10.36680782 -7.373397577 5.564917349 1.018369166 1.192581302 0 0.205166089 0.293214104 12.53961202 0.029273732 0.033316046 4.23E-08 7.373397577 0.174212136 GYAYVEFENPDEAEK ddPTM_HeLa_Curcumin_4h_R1 2 GYAYVEFENPDEAEK 15 0 H3BPG5;H3BV80;H3BMS0;H3BMM9;H3BTC0;Q15287-3;Q15287-2;Q15287 H3BPG5 RNPS1 RNA-binding protein with serine-rich domain 1 0 0 ; ; 154.15 0.003359 15405500 3972 2814.8 3572.7 3541.9 3479.9 4594.2 4037.8 3517.5 3820 3342.7 FALSE FALSE TRUE 3657.612009 3058.098769 3705.107405 3527.244556 3438.404465 3641.311133 4151.089801 4589.969557 3400.955557 3458.858576 1.057462145 0.884135244 1.071193668 1.019771256 0.994086456 1.052749354 1.20013285 1.327018569 0.983259501 1 11.75608031 -4.57810013 1.985659211 1.017221533 1.339297377 0.821384167 0.049556013 0.129810969 0.829197811 0.006916976 0.060056207 2.64E-05 4.57810013 0.322075844 GYDDRDYYSR ddPTM_HeLa_Curcumin_4h_R1 5 GYDDRDYYSR 10 1 P62995;H7C2L4;P62995-3;H7BXF3 P62995 TRA2B Transformer-2 protein homolog beta 0 0 ;;;; ;;;; 96.665 0.012754 1115878900 28041.9 20171.5 21181.7 22988.4 23074.6 28360.7 23054.2 24150.6 25702.2 22915.2 FALSE FALSE TRUE 25822.35403 21915.03458 21966.71244 22893.28009 22799.45047 22478.37113 23701.0388 31514.00676 22882.73296 23711.50149 1.089022306 0.924236476 0.926415918 0.965492636 0.961535501 0.947994421 0.99955875 1.32905994 0.965047826 1 14.5332994 -4.26047447 24.81183396 1.00839629 1.329060052 0.773939141 0.054787721 33.83479125 869885.9318 0.009503212 0.077502171 5.49E-05 4.26047447 0.320663762 GYDRYEDYDYR ddPTM_HeLa_Curcumin_4h_R1 3 GYDRYEDYDYR 11 1 Q13595;Q13595-4;Q13595-3 Q13595 TRA2A Transformer-2 protein homolog alpha 0 0 ;; ;; 110.93 0.0054933 198638000 8864.6 6581.5 6996.2 7157.8 6684.4 9302.9 7183.5 7362.6 9428.6 8130.9 FALSE FALSE TRUE 8162.957556 7150.375533 7255.485326 7128.18292 6604.692896 7373.373675 7385.049677 9607.422847 8394.306169 8413.44817 0.970227354 0.849874557 0.862367626 0.847236802 0.785016174 0.876379521 0.877767299 1.141912644 0.997724833 1 13.03848148 -7.380158348 4.859447421 0.987107899 0.883665853 0.199004377 0.089338216 0.253633636 8.993912302 0.01517563 0.01724377 4.17E-08 7.380158348 -0.103442045 GYDS(ph)EDDTWEPEQHLVNCEEYIHDFNR ddPTM_HeLa_Curcumin_4h_R1 2 GYDSEDDTWEPEQHLVNCEEYIHDFNR 27 0 Q9Y232-2;Q9Y232 Q9Y232-2 CDYL Chromodomain Y-like protein 1 0 GYDS(0.998)EDDT(0.002)WEPEQHLVNCEEYIHDFNR;GY(0.004)DS(0.99)EDDT(0.006)WEPEQHLVNCEEYIHDFNR ; 112.9 1.08E-08 24127000 2581.3 2380.32 2513.1 1878.99 2455.8 2674.5 2526.9 1968.31 2624.6 2092.69 TRUE FALSE FALSE 2376.987381 2586.064254 2606.237697 1871.215237 2426.516189 2119.778552 2597.798013 2568.438658 2336.687946 2165.410822 1.097707353 1.194260335 1.203576555 0.864138675 1.12058006 0.978926738 1.199679057 1.186120727 1.079096827 1 11.08042504 -8.936497041 0.934790154 1.004244947 1.101586624 0.038219165 0.106325962 0.910232866 1.532229918 0.053336293 0.020184041 1.16E-09 8.936497041 0.097341677 GYEEWLLNEIR ddPTM_HeLa_Curcumin_4h_R1 4 GYEEWLLNEIR 11 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75;A0A494C1A0;P35609-2;P35609;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2 0 0 ;;; ;;; 206.49 1.75E-06 121305000 8581.4 4434.01 9073.6 5779.03 8518.1 13892.9 11353.6 10969.3 5239.47 5636.37 FALSE FALSE TRUE 7902.173135 4817.266067 9409.875598 5755.117905 8416.527221 11011.35593 11672.15146 14313.78907 4664.71325 5832.233438 1.354913725 0.82597278 1.613425748 0.986777701 1.44310534 1.88801701 2.001317606 2.454255171 0.799815937 1 12.50983275 -4.84999572 0.903356948 1.155704503 2.597827989 0.784642841 0.244136006 0.339522168 0.347591371 0.035076938 0.392993497 1.41E-05 4.84999572 1.442123486 up GYEEWLLNEIRR ddPTM_HeLa_Curcumin_4h_R1 1 GYEEWLLNEIRR 12 1 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75;A0A494C1A0;P35609-2;P35609;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2 0 0 124.39 0.0045672 39160000 2540.4 1378.3 1984.8 1614 1734.8 5373.3 3829.4 4031.6 1735.2 1525.2 FALSE FALSE TRUE 2339.324659 1497.43411 2058.358434 1607.321696 1714.113643 4258.81701 3936.842658 5260.816281 1544.852901 1578.200586 1.482273343 0.948823694 1.304243866 1.018452096 1.086119 2.698527074 2.494513493 3.333426895 0.978869806 1 10.62406487 -5.23607354 5.85493637 1.191980579 2.822811636 0.904009434 0.256858423 0.042366271 4.953205879 0.0378802 0.095492527 5.81E-06 5.23607354 1.630831056 up GYEK(ac)GQPDEELKPK ddPTM_HeLa_Curcumin_4h_R1 1 GYEKGQPDEELKPK 14 2 P54577 P54577 YARS "Tyrosine--tRNA ligase, cytoplasmic;Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed" 0 1 GYEK(1)GQPDEELKPK 81.632 0.0066398 2126800 904.77 672.18 1010.8 1077.2 1003.7 1307.6 779.37 751.02 1019.6 921.89 FALSE TRUE FALSE 833.1564998 730.280244 1048.261137 1072.742832 991.731533 1036.38902 801.2370246 980.0025407 907.7524309 953.9256089 0.87339777 0.765552615 1.098891913 1.124556068 1.039631942 1.086446376 0.839936592 1.027336442 0.951596668 1 9.897732953 -6.714479515 24.99993792 0.925444661 1.033680368 0.329207111 0.093501075 148.1830013 78887.46924 0.016214716 0.022931031 1.93E-07 6.714479515 0.108235708 GYFDEEMNR ddPTM_HeLa_Curcumin_4h_R1 6 GYFDEEMNR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4;A0A075B730;P58107 Q15149;Q15149-3;Q15149-4;A0A075B730 PLEC;EPPK1 Plectin;Epiplakin 0 0 ;;;;; ;;;;; 194.9 0.0008641 293902900 24388.6 17786.2 21004.6 21207.8 21887.4 26019.6 18878.8 13379.3 23103.4 20209.8 FALSE FALSE TRUE 22458.21658 19323.55987 21783.04895 21120.04774 21626.40705 20622.84166 19408.48832 17458.58698 20569.01482 20912.08905 1.073934628 0.924037758 1.041648632 1.009944425 1.034158137 0.986168413 0.928098971 0.83485619 0.983594455 1 14.35204957 -4.341837651 1.193943929 1.026386504 0.761534905 0.634491348 0.03999798 0.586508148 0.75744238 0.006214947 0.184863296 4.55E-05 4.341837651 -0.264851599 GYFEYIEENK ddPTM_HeLa_Curcumin_4h_R1 2 GYFEYIEENK 10 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 0 ; ; 168.83 1.09E-09 7399800 2789.3 2873.6 2891 3063.5 3495.5 3717 3260.3 2964.5 2642.4 2563.4 FALSE FALSE TRUE 2568.523962 3121.981179 2998.143003 3050.824049 3453.818445 2946.052301 3351.775243 3868.362403 2352.535331 2652.477959 0.968348843 1.177005512 1.130317782 1.15017885 1.30211014 1.110679277 1.263639244 1.458395682 0.886919841 1 11.37312505 -1 0.210714214 0.949084133 3.292865056 0.751612836 0.080092087 18.33026222 0.215372302 0.067135534 14.53892752 0.1 1 2.343780923 GYFEYIEENKYSR ddPTM_HeLa_Curcumin_4h_R1 2 GYFEYIEENKYSR 13 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 0 ; ; 163.71 0.00015593 226080000 5541.3 4206.7 4475.7 4726.6 4564 7266.4 5160.2 4315 6014.6 5142.9 FALSE FALSE TRUE 5102.700258 4570.308403 4641.573379 4707.042582 4509.577281 5759.266731 5304.981324 5630.623636 5354.813428 5321.615392 0.95886303 0.85881975 0.872211356 0.884513862 0.847407591 1.082240317 0.996874245 1.058066625 1.006238338 1 12.37764853 -5.235818989 24.95456348 0.9473834 1.040841781 0.426791979 0.061441012 808.8556835 787833.9951 0.010087745 0.02570874 5.81E-06 5.235818989 0.093458381 GYGFVDFDS(ph)PAAAQK ddPTM_HeLa_Curcumin_4h_R1 2 GYGFVDFDSPAAAQK 15 0 E7EPF2;C9J9B2;E7ETU5;F6Y5H0;C9JIJ9;A0A1B0GUW5;P29558-2;P29558;Q6XE24-3;Q6XE24-4;Q6XE24-5;Q6XE24-2;Q6XE24 E7EPF2 RBMS1;RBMS3 "RNA-binding motif, single-stranded-interacting protein 1;RNA-binding motif, single-stranded-interacting protein 3" 1 0 GYGFVDFDS(1)PAAAQK;GYGFVDFDS(1)PAAAQK ; 210.08 1.86E-41 30005000 10040.1 8475.1 8568.6 9367.4 10154.1 12995.1 10387.8 7375.6 10574.3 8951.4 TRUE FALSE FALSE 9245.415491 9207.64988 8886.159854 9328.640181 10033.01899 10299.76978 10679.25371 9624.386487 9414.325746 9262.460484 0.998159777 0.994082501 0.959373578 1.007144937 1.083191557 1.111990685 1.152960785 1.039074499 1.01639578 1 13.17717977 -5.722990287 3.42420075 0.995395159 1.105302008 0.744378829 0.029159808 0.078029903 1.888144419 0.003897439 0.007961092 1.89E-06 5.722990287 0.109906849 GYGFVDFDS(ph)PSAAQK ddPTM_HeLa_Curcumin_4h_R1 2 GYGFVDFDSPSAAQK 15 0 Q15434;F8W1T6 Q15434 RBMS2 "RNA-binding motif, single-stranded-interacting protein 2" 1 0 GYGFVDFDS(0.998)PS(0.002)AAQK;GY(0.015)GFVDFDS(0.927)PS(0.058)AAQK ; 184.99 2.63E-05 120438000 11649.5 9299.9 10154.3 10128.2 11195.6 14419.1 12060.3 9205.8 10583.3 9889.4 TRUE FALSE FALSE 10727.42978 10103.74192 10530.62729 10086.29219 11062.09978 11428.41612 12398.67956 12012.60604 9422.338468 10233.05591 1.04831146 0.98736311 1.029079424 0.985657879 1.081016255 1.116813611 1.211630198 1.173902121 0.920774649 1 13.32094942 -5.194453305 1.737288011 1.018848429 1.193634355 0.78723701 0.039761665 0.090698181 0.514674704 0.003926119 0.014273361 6.39E-06 5.194453305 0.174785926 GYGFVHFETQEAAER ddPTM_HeLa_Curcumin_4h_R1 4 GYGFVHFETQEAAER 15 0 P11940;P11940-2;E7EQV3;A0A087WTT1;E7ERJ7;H0YAR2;H0YBN4;E5RGH3 P11940 PABPC1 Polyadenylate-binding protein 1;Polyadenylate-binding protein 0 0 ;;; ;;; 145.61 0.00038806 65393700 11302 9018.4 9377 9730.7 9051.5 13864.5 10423.4 9166 11077.7 10164.5 FALSE FALSE TRUE 10407.43477 9797.910311 9724.519869 9690.436942 8943.566774 10988.84641 10715.85255 11960.6712 9862.504025 10517.71562 0.989514753 0.931562581 0.924584788 0.921344263 0.85033358 1.044794023 1.0188384 1.13719287 0.937704002 1 13.36053377 -4.295913918 1.603136767 0.971831023 1.185799479 0.522787362 0.052688116 0.717824863 1.814050851 0.00831881 0.233591634 5.06E-05 4.295913918 0.213968456 GYGK(ac)INK ddPTM_HeLa_Curcumin_4h_R1 2 GYGKINK 7 1 P18124;A8MUD9 P18124 RPL7 60S ribosomal protein L7 0 1 ; GYGK(1)INK;GYGK(1)INK 110.61 0.013257 11523300 11549.8 10338.8 12481.9 12983.1 15614.3 15699.7 14547.3 9561.6 10521.4 7998.5 FALSE TRUE FALSE 10635.62114 11232.4398 12944.49019 12929.37937 15428.10967 12443.40525 14955.45809 12476.88782 9367.228743 8276.44728 1.285046685 1.357157174 1.564015302 1.56218954 1.864098103 1.503471819 1.806990074 1.507517344 1.131793441 1 13.0147959 -7.333773706 0.552528643 1.037112238 1.695189719 0.781667866 0.120909438 0.203714338 0.14372694 0.040173535 0.044880909 4.64E-08 7.333773706 0.65807748 GYGYGQGAGTLS(ph)TDKGESLGIK ddPTM_HeLa_Curcumin_4h_R1 1 GYGYGQGAGTLSTDKGESLGIK 22 1 E9PP21;P21291;E9PND2;E9PS42 E9PP21 CSRP1 Cysteine and glycine-rich protein 1 1 0 GY(0.003)GY(0.036)GQGAGT(0.14)LS(0.59)T(0.175)DKGES(0.056)LGIK 48.374 0.015692 13402000 990.18 567.44 690.16 902.2 716.92 1328.1 1090.2 1008.5 872.93 684.09 TRUE FALSE FALSE 911.8062082 616.4869851 715.7379367 898.4669355 708.3711972 1052.637089 1120.788078 1315.987007 777.171763 707.8620766 1.288112809 0.87091399 1.011126264 1.269268358 1.000719237 1.487065241 1.583342455 1.859100877 1.097914112 1 9.467324475 -4.843888891 1.493616732 1.1092449 1.840273331 0.793960807 0.135307722 0.193642027 0.726027774 0.022618845 0.151455509 1.43E-05 4.843888891 0.731028431 GYIFLEYAS(ph)PAHAVDAVK ddPTM_HeLa_Curcumin_4h_R1 2 GYIFLEYASPAHAVDAVK 18 0 P55884-2;P55884;C9JZG1 P55884-2 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 0 GYIFLEY(0.001)AS(0.999)PAHAVDAVK;GYIFLEYAS(1)PAHAVDAVK ; 138.28 0.00014384 72313000 5282.6 3942.1 4408.3 4301.2 3922.8 4764 4271 2984.3 5252.4 4657.1 TRUE FALSE FALSE 4864.476636 4282.837558 4571.675476 4283.402774 3876.023172 3775.892699 4390.832765 3894.199332 4676.224861 4818.933878 1.009450795 0.88875209 0.948690227 0.888869381 0.804332093 0.78355354 0.911162692 0.808103915 0.97038577 1 12.23449829 -6.621745291 0.930315374 1.005732728 0.830157977 0.685225196 0.043754083 0.182968561 0.31656905 0.008178266 0.014102115 2.39E-07 6.621745291 -0.175574751 GYISPYFINTSK ddPTM_HeLa_Curcumin_4h_R1 2 GYISPYFINTSK 12 0 P10809;E7ESH4 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 ; ; 222.18 7.46E-29 5767600 1717.33 1631.34 2021.34 1535.78 1820.19 4549.9 2981.1 2638.6 1801.56 1085.04 FALSE FALSE TRUE 1581.401518 1772.34576 2096.252639 1529.425349 1798.485423 3606.199452 3064.741643 3443.096993 1603.933375 1122.745059 1.408513451 1.578582552 1.867078035 1.362219621 1.601864473 3.211948628 2.729686154 3.066677484 1.428581994 1 10.13281466 -4.396340359 0.361903833 1.094559521 4.723082443 0.768596946 0.357415606 1.739029416 0.169159355 0.114676401 2.703410346 4.01E-05 4.396340359 3.628522922 up GYIWNYGAIPQTWEDPGHNDK ddPTM_HeLa_Curcumin_4h_R1 2 GYIWNYGAIPQTWEDPGHNDK 21 0 Q15181;Q5SQT6 Q15181 PPA1 Inorganic pyrophosphatase 0 0 ; ; 109.77 3.33E-05 49538000 2754.1 2295 2718.6 1666.75 2340.9 6882.4 4745.6 4182.9 2688.1 2493 FALSE FALSE TRUE 2536.110079 2493.369574 2819.353708 1659.85343 2312.986296 5454.912659 4878.748764 5458.246954 2393.222155 2579.631564 0.983128798 0.966560345 1.09292883 0.64344593 0.89663436 2.114609208 1.891257973 2.115901755 0.927737972 1 11.33294931 -5.262102719 24.99999638 0.965345409 2.025656526 0.941042443 0.127149851 9.606775222 362070.6898 0.017780903 0.042110394 5.47E-06 5.262102719 1.060311117 GYLDK(ac)LEPSK ddPTM_HeLa_Curcumin_4h_R1 1 GYLDKLEPSK 10 1 P25705;P25705-2;P25705-3 P25705 ATP5A1 "ATP synthase subunit alpha, mitochondrial" 0 1 GYLDK(1)LEPSK 143.4 1.72E-05 2214700 1365.5 1389.9 1337.8 1175.2 2437.3 4287.1 2471.4 1953.9 2899.4 1333 FALSE TRUE FALSE 1257.419234 1510.036763 1387.380045 1170.337334 2408.236789 3397.907134 2540.740833 2549.635115 2581.343074 1379.321651 0.911621472 1.094767679 1.005842288 0.848487612 1.745957361 2.46346248 1.842022005 1.848470307 1.871458389 1 10.42974321 -5.650127216 4.335848762 0.966129666 2.040543022 0.595715585 0.335288399 0.045982027 1.524901446 0.024313394 0.049829873 2.24E-06 5.650127216 1.074413356 GYLGPEQLPDCLK ddPTM_HeLa_Curcumin_4h_R1 1 GYLGPEQLPDCLK 13 0 P40926;P40926-2 P40926 MDH2 "Malate dehydrogenase, mitochondrial" 0 0 162.36 7.67E-24 0 282.87 347.08 317.24 460.78 286.03 433.07 434.49 246.21 321.96 232.05 FALSE FALSE TRUE 260.480541 377.0800486 328.9971935 458.8734145 282.6192791 343.2464003 446.68062 321.2782956 286.6417935 240.1137202 1.084821562 1.570422749 1.370172405 1.911067031 1.177022616 1.429515981 1.860287782 1.338025563 1.193775155 1 7.907574032 -7.302488766 4.932581924 1.037474489 1.528287337 0.440767842 0.21915847 0.10909535 6.458278222 0.034390015 0.039676685 4.98E-08 7.302488766 0.490812848 GYNVNDEK ddPTM_HeLa_Curcumin_4h_R1 2 GYNVNDEK 8 0 P80723;P80723-2;U3KQP0 P80723 BASP1 Brain acid soluble protein 1 0 0 ; ; 146.81 0.00031815 8704800 7053.3 5519.4 5806.3 6896.6 6347.8 9248.8 7329.6 6781.4 8085.3 6436.7 FALSE FALSE TRUE 6495.023862 5996.472342 6021.486586 6868.063697 6272.106631 7330.494625 7535.248849 8849.017642 7198.362818 6660.374846 0.975173922 0.90032055 0.904076231 1.031182757 0.94170475 1.100612923 1.13135507 1.328606549 1.080774429 1 12.70138766 -4.252137331 1.027465931 0.97465226 1.509654428 0.789017001 0.056349725 0.511513909 0.410971263 0.007146416 0.301202517 5.60E-05 4.252137331 0.535002168 GYQSLSDS(ph)PPGSR ddPTM_HeLa_Curcumin_4h_R1 2 GYQSLSDSPPGSR 13 0 Q9NPR2 Q9NPR2 SEMA4B Semaphorin-4B 1 0 GYQSLS(0.15)DS(0.85)PPGSR;GYQSLS(0.384)DS(0.574)PPGS(0.042)R ; 153.14 0.00044122 13293700 3696.2 2476.8 2965.6 2821 3346.4 4447.6 2317.5 1267.52 3725.3 3357.5 TRUE FALSE FALSE 3403.64187 2690.883556 3075.507745 2809.327449 3306.496366 3525.117625 2382.522813 1653.981013 3316.64391 3474.172875 0.979698476 0.774539337 0.885248908 0.808632026 0.951736279 1.01466385 0.685781306 0.476079076 0.954657131 1 11.76245383 -4.554602199 3.200135121 0.952758225 0.495698814 0.745003581 0.08190443 0.093366802 1.848013577 0.01310755 0.074800138 2.79E-05 4.554602199 -0.457059412 GYRDDRS(ph)PAREPGDVSAR ddPTM_HeLa_Curcumin_4h_R1 2 GYRDDRSPAREPGDVSAR 18 3 A0A1W2PR91;A0A1W2PQT1;C9J366;P0DPB3-2;P0DPB3;B3KU38-2;B3KU38 A0A1W2PR91 IQCJ-SCHIP1 1 0 GY(0.001)RDDRS(0.998)PAREPGDVS(0.001)AR;GY(0.001)RDDRS(0.999)PAREPGDVSAR ; 58.461 0.015137 51529000 1035.71 940.47 963.55 974.45 1088 1132.85 853.51 567.75 1132.06 1183.81 TRUE FALSE FALSE 953.7324606 1021.760036 999.2600106 970.4179841 1075.026311 897.8841401 877.4571935 740.8543614 1007.87585 1224.947309 0.7785906 0.834125703 0.815757546 0.792212021 0.877610247 0.732998173 0.716322398 0.604805085 0.822791187 1 10.25850398 -13.52287875 0.088149895 1.761897431 0.554726267 0.432785365 0.074558793 63.08831293 0.422278076 9.273562939 0.831726305 3.00E-14 13.52287875 -1.207171165 GYS(ph)FTTTAER ddPTM_HeLa_Curcumin_4h_R1 1 GYSFTTTAER 10 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 1 0 GYS(0.598)FT(0.306)T(0.088)T(0.008)AER 126.03 0.003523 17055000 1872.9 1611.2 1533.4 1579.4 1941.3 2052.3 1635.9 1478.7 1735.9 1809.9 TRUE FALSE FALSE 1724.657989 1750.464949 1590.229153 1572.864861 1918.151265 1626.629846 1681.798951 1929.548823 1545.476113 1872.79389 0.920901119 0.934681044 0.849121284 0.839849419 1.024219096 0.868557856 0.898016039 1.030304954 0.82522488 1 10.87097642 -8.957833669 0.786651456 0.999860852 0.916998437 0 0.081817884 0.807953242 0.922066792 0.038801628 0.012335494 1.10E-09 8.957833669 -0.082862415 GYSDEIYVVPDDS(ph)QNRIK ddPTM_HeLa_Curcumin_4h_R1 1 GYSDEIYVVPDDSQNRIK 18 1 Q13017-2;Q13017;A0A0A0MSK6 Q13017-2 ARHGAP5 Rho GTPase-activating protein 5 1 0 GYSDEIYVVPDDS(1)QNRIK 98.562 0.00061043 0 1946.7 1496.1 1542 1859.6 1464.2 2588.2 2279.5 934.76 2315.5 1373.4 TRUE FALSE FALSE 1792.616641 1625.416218 1599.147876 1851.905468 1446.740371 2051.378145 2343.456635 1219.764021 2061.495443 1421.125548 1.261406245 1.143752725 1.125268544 1.303125871 1.018024321 1.443488331 1.6490145 0.858308418 1.450607546 1 10.4728183 -13.09599117 0.211147207 5.24E-09 1.285493101 0 0.251725062 55.3691986 0.809231916 22.96561248 0.182436256 8.02E-14 13.09599117 1.285493096 GYSFSLTTFS(ph)PSGK ddPTM_HeLa_Curcumin_4h_R1 1 GYSFSLTTFSPSGK 14 0 H3BT36;A0A024RA52;P25787 H3BT36 PSMA2 Proteasome subunit alpha type;Proteasome subunit alpha type-2 1 0 GYSFSLT(0.002)T(0.016)FS(0.973)PS(0.01)GK 101.72 0.0045517 19064000 1499.4 1171.4 1147.3 1328.6 1253.7 1824.5 1422.9 1136.9 1394.3 1406.4 TRUE FALSE FALSE 1380.720908 1272.650596 1189.819947 1323.102605 1238.750446 1446.078134 1462.822744 1483.535576 1241.348778 1455.272295 0.94877152 0.87451029 0.81759266 0.909178722 0.851215577 0.993682171 1.005188341 1.019421301 0.853001038 1 10.50707341 -5.021427467 24.43319702 0.942251083 1.009087467 0.199176491 0.064011559 812.6150949 926607.6471 0.010168388 0.026248177 9.52E-06 5.021427467 0.066836384 GYSFTT(ph)TAER ddPTM_HeLa_Curcumin_4h_R1 2 GYSFTTTAER 10 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 1 0 GYS(0.047)FT(0.157)T(0.781)T(0.015)AER;GYS(0.046)FT(0.03)T(0.92)T(0.004)AER ; 146.11 0.0031386 93163000 2460.46 1629.29 2278.9 2306.3 2361.53 2753.07 1996.65 2176.25 2149.67 2097.14 TRUE FALSE FALSE 2265.711995 1770.118568 2363.358039 2296.757142 2333.370297 2182.052249 2052.670625 2839.778607 1913.856579 2170.015459 1.044099472 0.815717031 1.089097328 1.058405889 1.075278191 1.005546868 0.945924425 1.308644413 0.881955274 1 11.0834896 GYSFTTTAER ddPTM_HeLa_Curcumin_4h_R1 6 GYSFTTTAER 10 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 0 0 ;;;;; ;;;;; 218.58 7.11E-13 1035253000 16405.2 10953.94 13352.8 12926.2 14621 17903.7 14892 14574.5 14118.7 12874.88 FALSE FALSE TRUE 15106.71111 11900.74976 13847.66651 12872.71481 14446.65412 14190.2708 15309.82944 19018.19796 12569.91393 13322.28112 1.133943277 0.8932967 1.039436594 0.966254554 1.084397934 1.065153233 1.14918979 1.427548164 0.943525648 1 13.70155351 -4.105339119 1.550197512 1.043759815 1.693968982 0.750608848 0.071020243 0.656355399 1.083008549 0.010562532 0.722807268 7.85E-05 4.105339119 0.650209166 GYSSLDQSPDEKPLVALDT(ph)DSDDDFDMSR ddPTM_HeLa_Curcumin_4h_R1 1 GYSSLDQSPDEKPLVALDTDSDDDFDMSR 29 1 A0A0A0MRW1;A0A0A0MRW0;Q8IW50-3;Q8IW50-2;Q8IW50-4;Q5T586;A0A0A0MRW2;Q5T593;A0A0A0MRW3;Q8IW50-5;Q8IW50-6;Q8IW50 A0A0A0MRW1 FAM219A Protein FAM219A 1 0 GYSSLDQS(0.001)PDEKPLVALDT(0.498)DS(0.498)DDDFDMS(0.003)R 59.628 0.001336 12723000 2755.2 2206.6 2059.7 2282.4 2395.9 2570.8 1329.8 1154.9 2825.2 2210.1 TRUE FALSE FALSE 2537.123013 2397.328672 2136.034294 2272.956034 2367.330457 2037.587101 1367.110609 1507.023693 2515.282628 2286.90081 1.109415415 1.048287123 0.934030144 0.993902325 1.035169714 0.890981844 0.59780057 0.658980786 1.099865205 1 11.15917808 -4.928062993 2.780048167 1.037806307 0.622283327 0.901676745 0.052465621 0.061872963 0.951565646 0.008651963 0.031842997 1.18E-05 4.928062993 -0.415522981 GYT(ph)SDSEVYTDHGR ddPTM_HeLa_Curcumin_4h_R1 1 GYTSDSEVYTDHGR 14 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 0 GYT(0.599)S(0.4)DS(0.001)EVYTDHGR 160.04 0.000285 11029000 2353 2337.1 2330 2482 3007.6 2471.3 1803.4 1628.1 2254.4 2447.1 TRUE FALSE FALSE 2166.757567 2539.10851 2416.35185 2471.730142 2971.736334 1958.724523 1853.99855 2124.500195 2007.09796 2532.136543 0.855703289 1.002753393 0.954273914 0.976144098 1.173608249 0.773546169 0.732187431 0.839014863 0.792649972 1 11.30613949 -5.113927743 19.37613231 0.955624451 0.776432346 0.425215152 0.097244626 2.771946424 462.3883748 0.012882686 0.032844891 7.69E-06 5.113927743 -0.179192105 GYT(ph)SDSEVYTDHGRPGK ddPTM_HeLa_Curcumin_4h_R1 1 GYTSDSEVYTDHGRPGK 17 1 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 0 GYT(0.878)S(0.122)DSEVYTDHGRPGK 143.67 0.00010437 363250000 8883.5 7509.5 8347.8 8968.8 7694.1 8146.8 5839.5 4149.4 9068.3 9061.4 TRUE FALSE FALSE 8180.361601 8158.587718 8657.176811 8931.689482 7602.352883 6457.061847 6003.340654 5414.532959 8073.530178 9376.282976 0.872452508 0.870130279 0.923305838 0.952583183 0.810806681 0.68865902 0.640268715 0.577471155 0.861058716 1 13.1948004 -5.27725014 1.433481436 0.933476274 0.596014561 0.881972365 0.045584767 0.117582063 0.446603738 0.008467179 0.032458099 5.28E-06 5.27725014 -0.337461713 GYTS(ph)DDDTWEPEIHLEDCK ddPTM_HeLa_Curcumin_4h_R1 3 GYTSDDDTWEPEIHLEDCK 19 0 Q99549-2;Q99549 Q99549-2 MPHOSPH8 M-phase phosphoprotein 8 1 0 GYT(0.413)S(0.584)DDDT(0.003)WEPEIHLEDCK;GYT(0.162)S(0.837)DDDT(0.001)WEPEIHLEDCK;GYT(0.078)S(0.902)DDDT(0.02)WEPEIHLEDCK ;; 201.48 1.07E-30 15095400 7182.4 4881.9 6933.5 7088.2 8223.4 9792.8 6936.7 5844.7 6103.3 5940.7 TRUE FALSE FALSE 6613.905461 5303.869683 7190.461609 7058.870907 8125.341326 7761.662892 7131.325133 7626.722124 5433.78326 6147.138883 1.07593233 0.862819237 1.169724932 1.14831811 1.321808646 1.262646418 1.160104769 1.240694617 0.883953228 1 12.58569937 -6.540364975 24.99618368 1.023518637 1.223166039 0.680178639 0.08353345 111.8922645 159946.9803 0.01141365 0.01614321 2.88E-07 6.540364975 0.199647403 GYTS(ph)DSEVYTDHGRPGK ddPTM_HeLa_Curcumin_4h_R1 2 GYTSDSEVYTDHGRPGK 17 1 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 0 GYT(0.426)S(0.574)DSEVYTDHGRPGK;GY(0.001)T(0.206)S(0.696)DS(0.042)EVY(0.007)T(0.048)DHGRPGK ; 110.26 0.00050837 222478000 5189.9 4275.8 4641.8 5123.3 4418.5 4765.2 3501.8 2477 5421.3 4924.4 TRUE FALSE FALSE 4779.113939 4645.381099 4813.829191 5102.101142 4365.812273 3776.843805 3600.051083 3232.225897 4826.596953 5095.522533 0.937904583 0.911659416 0.944717477 1.001291057 0.856793831 0.741208341 0.706512641 0.634326681 0.947223159 1 12.31501438 -5.273036988 1.559485923 0.965678831 0.662331996 0.929327532 0.032670356 0.08022867 0.364969594 0.0056379 0.020385001 5.33E-06 5.273036988 -0.303346835 SDTSISDFLS(ph)EEDDIVPSKK ddPTM_HeLa_Curcumin_4h_R1 1 SDTSISDFLSEEDDIVPSKK 20 1 Q4AC94;Q4AC94-2;Q4AC94-4;Q4AC94-1;Q4AC94-3 Q4AC94 C2CD3 C2 domain-containing protein 3 1 0 SDT(0.001)S(0.001)IS(0.003)DFLS(0.996)EEDDIVPSKK 95.153 0.00039329 5054400 2242.1 1740.4 1566.7 1781.8 2037.9 2124.9 1173.1 484.89 1882.3 1416.5 TRUE FALSE FALSE 2064.635419 1890.832421 1624.76328 1774.427384 2013.599373 1684.171787 1206.014029 632.7307288 1675.816399 1465.72327 1.408612022 1.290033706 1.108506165 1.210615551 1.373792322 1.149038036 0.822811546 0.431684986 1.143337514 1 10.51739703 -4.492866113 2.077403395 1.211763556 0.382600908 0.822982809 0.115683273 0.18767536 1.231938251 0.02323993 0.242540832 3.21E-05 4.492866113 -0.829162648 down GYY(ph)SPYS(ph)VSGSGSTAGSR ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 GY(0.013)Y(0.771)S(0.219)PY(0.003)S(0.99)VS(0.003)GS(0.001)GSTAGSR 165.24 0.0017729 83486000 5394.8 4678 4518.4 3758.1 5006.5 5801.7 6959.4 6460.1 5186.9 4483.9 TRUE FALSE FALSE 4967.795887 5082.345475 4685.855879 3742.549978 4946.800757 4598.362021 7154.662034 8429.754751 4617.910047 4639.715191 1.070711387 1.095400314 1.009944724 0.806633559 1.066186297 0.991087132 1.542047677 1.816869011 0.995300327 1 12.17982053 -4.628519881 3.107838189 1.019552356 1.782896887 0.921240532 0.080499987 0.048110133 0.876972583 0.011652886 0.059082076 2.35E-05 4.628519881 0.763344531 GYYS(ph)PGIVSTR ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPGIVSTR 11 0 Q12789-3;Q12789 Q12789-3 GTF3C1 General transcription factor 3C polypeptide 1 1 0 GYY(0.001)S(0.994)PGIVS(0.005)TR 120.55 0.0041275 35663000 3220.1 2366.7 3130.5 2785.5 2796.1 3415.9 2651.8 1349 2809.5 3099.6 TRUE FALSE FALSE 2965.225687 2571.267002 3246.519084 2773.974339 2762.758334 2707.403835 2726.202371 1760.30389 2501.304879 3207.310869 0.924520824 0.801689361 1.012224638 0.864891011 0.861393998 0.844135148 0.8499963 0.548841058 0.779876034 1 11.64714848 -3.446683316 0.526224964 0.955572869 1.67E-49 0.480197249 0.089088721 3.497692308 0.352333578 0.013595786 2.496502552 0.000357533 3.446683316 -0.955572869 TTHLAGALS(ph)PGGGQSAPAFPESGPSLR ddPTM_HeLa_Curcumin_4h_R1 2 TTHLAGALSPGGGQSAPAFPESGPSLR 27 0 A0A2R8Y4Z8 A0A2R8Y4Z8 1 0 TTHLAGALS(1)PGGGQSAPAFPESGPSLR;TTHLAGALS(0.998)PGGGQS(0.002)APAFPESGPSLR ; 99.603 8.68E-07 34435000 2995.8 2597.6 2317 2219.7 2843.2 3699.6 2769.8 6623.1 3252.7 2416.4 TRUE FALSE FALSE 2758.679269 2822.124969 2402.870058 2210.51547 2809.296697 2932.261257 2847.513133 8642.452701 2895.886948 2500.36972 1.103308541 1.128683069 0.961005902 0.884075444 1.123552519 1.17273107 1.138836833 3.45646991 1.158183498 1 11.28792572 -4.260296542 5.279831984 1.052467655 3.558259942 0.984842036 0.088679929 0.012808694 1.242728949 0.012405188 0.115859989 5.49E-05 4.260296542 2.505792286 up S(ph)VKEDSNLTLQEK ddPTM_HeLa_Curcumin_4h_R1 1 SVKEDSNLTLQEK 13 1 P46940;H0YLE8 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 1 0 S(0.999)VKEDS(0.001)NLTLQEK 109.99 0.0032419 0 1153 766.93 822.4 1023.5 932.46 1493.2 1702.5 1964.4 798.36 679.42 TRUE FALSE FALSE 1061.738833 833.2200118 852.8788675 1019.265028 921.3410235 1183.493488 1750.267568 2563.336517 710.7819054 703.0297944 1.510233054 1.185184495 1.213147543 1.449817684 1.310529128 1.683418679 2.489606531 3.646127856 1.011026718 1 9.457442022 -4.260200708 1.097467184 1.246391354 4.894040412 0.963019533 0.150231785 0.277016186 0.262472786 0.029047887 1.169810452 5.49E-05 4.260200708 3.647649058 up GYYS(ph)PYSVS(ph)GSGSTAGSR ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 GY(0.041)Y(0.082)S(0.879)PYS(0.047)VS(0.502)GS(0.425)GS(0.025)TAGSR 160.43 8.01E-05 138190000 10427 7630.5 8110.3 8351.6 8733.5 10708 11956 11480 10186 8255.1 TRUE FALSE FALSE 9601.691947 8290.046419 8410.874853 8317.043292 8629.358717 8487.040096 12291.45318 14980.19915 9068.621284 8541.964111 1.124061378 0.970508224 0.984653499 0.973668724 1.010231207 0.993570095 1.438949289 1.753718344 1.061655278 1 13.06035212 -4.554861237 2.783514123 1.034638286 1.739741347 0.953074075 0.053503424 0.053181171 0.757015277 0.009706379 0.062615758 2.79E-05 4.554861237 0.705103061 GYYS(ph)PYSVSGSGS(ph)TAGSR ddPTM_HeLa_Curcumin_4h_R1 6 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 GYYS(1)PYSVSGSGS(0.563)T(0.416)AGS(0.02)R;GY(0.011)Y(0.017)S(0.803)PY(0.04)S(0.071)VS(0.194)GS(0.22)GS(0.566)T(0.076)AGS(0.002)R;GY(0.004)Y(0.001)S(0.993)PYS(0.001)VS(0.001)GS(0.004)GS(0.91)T(0.085)AGSR;GYY(0.001)S(0.994)PYS(0.005)VS(0.001)GS(0.029)GS(0.866)T(0.103)AGS(0.001)R;GY(0.111)Y(0.035)S(0.854)PYSVS(0.007)GS(0.143)GS(0.76)T(0.09)AGSR;GYY(0.003)S(0.987)PY(0.001)S(0.007)VS(0.005)GS(0.002)GS(0.974)T(0.021)AGSR ;;;;; 217.67 1.15E-16 391419100 20488.7 17505.4 19655.4 20956.8 22474.7 31720 31391.8 24983.1 22303.3 20219.9 TRUE FALSE FALSE 18866.99778 19018.48877 20383.84641 20870.08631 22206.70388 25140.91444 32272.56942 32600.33218 19856.68379 20922.54002 0.901754651 0.908995215 0.974252954 0.997492957 1.061377054 1.201618657 1.542478561 1.558144095 0.949057035 1 14.35277039 -4.936794001 1.35175384 0.95234402 1.623090046 0.971444368 0.039683697 0.069762783 0.212302324 0.007173265 0.045405016 1.16E-05 4.936794001 0.670746026 IISIFSGT(ph)EK ddPTM_HeLa_Curcumin_4h_R1 1 IISIFSGTEK 10 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 0 IIS(0.001)IFS(0.143)GT(0.856)EK 177.44 0.0010423 45924000 1848.7 1404.3 1954.7 2159.9 1637.7 3036.3 3232.3 24813 0 1735 TRUE FALSE FALSE 1702.373444 1525.681435 2027.142902 2150.962906 1618.171497 2406.537154 3322.989639 32378.36947 0 1795.291121 0.948243672 0.849823974 1.129144392 1.19811371 0.901342116 1.340471819 1.850947515 18.03516382 0 1 10.81000209 -4.260196323 4.843703549 1.022427183 18.97156349 0.995262509 0.352552048 0.004264326 0.289784214 0.02591048 0.256859946 5.49E-05 4.260196323 17.94913631 up GYYS(ph)PYSVSGSGSTAGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 GYY(0.001)S(0.603)PY(0.011)S(0.169)VS(0.076)GS(0.015)GS(0.135)T(0.023)AGS(0.968)R 113.81 0.00131 148520000 3184.9 2453.4 3728.8 3131.2 3374 4621.3 4331.9 4960.5 3156 3538.2 TRUE FALSE FALSE 2932.811804 2665.460964 3866.992608 3118.243924 3333.767254 3662.790287 4453.441455 6472.933615 2809.794696 3661.152187 0.801062522 0.728038833 1.056222853 0.851711091 0.910578715 1.000447428 1.216404353 1.76800452 0.767461868 1 11.83808203 -4.101425193 1.272667816 0.896802845 2.418359904 0.888352257 0.096635786 0.482464994 0.509547302 0.015011374 1.049572562 7.92E-05 4.101425193 1.521557059 GYYS(ph)PYSVSGSGSTAGSR ddPTM_HeLa_Curcumin_4h_R1 3 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 GY(0.001)YS(0.954)PYS(0.044)VS(0.001)GSGSTAGSR;GYYS(0.984)PYS(0.016)VSGSGSTAGSR;GYYS(0.999)PYS(0.001)VSGSGSTAGSR ;; 243.01 5.31E-32 566730000 6101.01 5007.24 5338.36 5124.44 5673.19 6511.2 5642.25 2290.68 5841.11 4960.67 TRUE FALSE FALSE 5618.108621 5440.043514 5536.204318 5103.236425 5605.540915 5160.703724 5800.55635 2989.097787 5200.354847 5133.052913 1.094496534 1.059806631 1.078540278 0.994191276 1.092048145 1.005386816 1.130040241 0.582323587 1.013111483 1 12.32560142 -4.255450417 24.99992552 1.050182517 0.582323384 0.908352385 0.044749012 142.8971079 596483.0866 0.006346221 0.076959371 5.55E-05 4.255450417 -0.467859133 GYYSPYS(ph)VSGSGSTAGSR ddPTM_HeLa_Curcumin_4h_R1 2 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 GYY(0.001)S(0.09)PY(0.008)S(0.875)VS(0.024)GS(0.001)GS(0.001)T(0.001)AGSR;GYYS(0.277)PYS(0.425)VS(0.273)GS(0.019)GS(0.003)T(0.001)AGSR ; 174.18 4.17E-06 811230000 7668.5 6560.2 6018.4 6737.5 6640.6 8656.2 7056.8 3414.6 7719.6 6186.3 TRUE FALSE FALSE 7061.530133 7127.234456 6241.447198 6709.62201 6561.415182 6860.806545 7254.794816 4455.695821 6872.779193 6401.273465 1.103144581 1.113408839 0.975032114 1.048169875 1.025017165 1.07178776 1.13333618 0.69606397 1.073658114 1 12.64414323 -4.253504006 24.9973611 1.053171234 0.696063797 0.837612858 0.048030395 328.1383322 1033650.772 0.007422259 0.109838342 5.58E-05 4.253504006 -0.357107437 STS(ph)VPENPK ddPTM_HeLa_Curcumin_4h_R1 2 STSVPENPK 9 0 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;D6RDA9;Q3MSN4;P04150-9;P04150-8;P04150-13;P04150-12;P04150-11 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 0 ST(0.018)S(0.982)VPENPK;ST(0.006)S(0.994)VPENPK ; 130.41 0.003854 192144000 8881.2 5767.3 9943 10379.3 8571.8 9827.2 15097.1 101490 0 6791.8 TRUE FALSE FALSE 8178.243649 6265.799713 10311.49633 10336.35321 8469.586883 7788.927945 15520.68399 132433.8338 0 7027.814544 1.163696566 0.891571579 1.467240813 1.470777742 1.205152303 1.108300154 2.20846522 18.8442414 0 1 12.77886041 -4.260195393 4.538823873 1.144381152 20.01334101 0.99430582 0.402088702 0.005302006 0.279291147 0.030502109 0.318553916 5.49E-05 4.260195393 18.86895986 up GYYSPYSVS(ph)GSGS(ph)TAGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 3 0 GYYS(0.014)PY(0.005)S(0.223)VS(0.488)GS(0.278)GS(0.639)T(0.352)AGS(1)R 85.046 0.011805 3977300 2903 2689 3546.8 3026.8 3714.5 4467.2 4667.3 5050 2806.5 3472.8 TRUE FALSE FALSE 2673.224487 2921.425178 3678.247528 3014.275904 3670.207014 3540.652364 4798.251877 6589.721753 2498.633972 3593.479542 0.743909755 0.812979494 1.023589389 0.838818162 1.02135186 0.985299157 1.335266229 1.833799713 0.69532439 1 11.81116576 -3.987151125 0.984097821 0.880570275 2.834398831 0.894816495 0.103568857 0.711921545 0.370378644 0.01678225 1.667905177 0.000103003 3.987151125 1.953828556 GYYSPYSVS(ph)GSGST(ph)AGSR ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 GYYS(0.067)PYS(0.213)VS(0.717)GS(0.004)GS(0.213)T(0.783)AGS(0.003)R 174.35 1.77E-05 91276000 3185.9 2642 2842.6 3104.7 2816.3 4139.9 3619.7 4265.2 3281.7 3475.1 TRUE FALSE FALSE 2933.732653 2870.362707 2947.949257 3091.853574 2782.717462 3281.238074 3721.25904 5565.639845 2921.70572 3595.859466 0.815864102 0.79824107 0.819817705 0.859837155 0.773867135 0.912504536 1.034873324 1.547791258 0.81251944 1 11.81212092 -4.230883539 2.145966165 0.882399839 1.760841684 0.902439597 0.068640456 0.216229293 1.031920834 0.012799602 0.37382859 5.88E-05 4.230883539 0.878441845 GYYSPYSVS(ph)GSGSTAGSR ddPTM_HeLa_Curcumin_4h_R1 2 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 GYYS(0.012)PYS(0.308)VS(0.68)GSGSTAGSR;GYYSPYS(0.048)VS(0.943)GS(0.009)GSTAGSR ; 264 1.59E-53 419930000 11034.8 7979 9574.5 8408 8692.6 9026.2 7592.1 7825.5 10628.8 7750 TRUE FALSE FALSE 10161.38394 8668.669206 9929.339393 8373.209924 8588.946422 7154.064374 7805.113893 10211.45893 9462.847232 8019.311923 1.267114191 1.080974189 1.238178473 1.044130719 1.07103284 0.892104515 0.973289725 1.273358491 1.180007378 1 12.96926274 -6.047631227 24.57600863 1.13323473 1.038119549 0.149531636 0.115564345 589.1464631 303977.8012 0.020206947 0.033510172 8.96E-07 6.047631227 -0.095115182 GYYSPYSVSGS(ph)GSTAGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 GY(0.007)Y(0.272)S(0.025)PY(0.007)S(0.031)VS(0.076)GS(0.437)GS(0.144)T(0.087)AGS(0.914)R 108.25 0.0020359 262050000 7217.7 5951.5 7616.8 8199.3 7920.8 11459 9810.8 11409 7248.4 8784.8 TRUE FALSE FALSE 6646.411429 6465.921141 7899.085308 8165.373469 7826.349633 9082.27423 10086.06464 14887.55158 6453.268655 9090.071146 0.731172652 0.71131689 0.868979481 0.898273879 0.860977819 0.99914226 1.109569384 1.637781635 0.709924989 1 13.15007587 -3.602367679 0.986164296 0.856885841 3.573512967 0.876089504 0.091995252 1.834025165 0.546739918 0.017275026 7.244518787 0.000249823 3.602367679 2.716627127 GYYSPYSVSGS(ph)GSTAGS(ph)RTGSR ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPYSVSGSGSTAGSRTGSR 22 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 GYYS(0.001)PY(0.001)S(0.018)VS(0.035)GS(0.452)GS(0.076)T(0.418)AGS(0.398)RT(0.165)GS(0.436)R 52.866 0.014685 66691000 3132.5 2212.9 2500.4 2677.8 1848.4 3610.4 2631.1 3120 3676.4 2769.4 TRUE FALSE FALSE 2884.55932 2404.173216 2593.067024 2666.719973 1826.359037 2861.562342 2704.921585 4071.273637 3273.108118 2865.636444 1.006603376 0.838966583 0.904883461 0.930585587 0.637331034 0.998578291 0.943916522 1.420722313 1.142192383 1 11.48463987 -4.260740146 24.66686398 0.953199831 1.420722487 0.56983778 0.125926159 26.44544576 932679.7826 0.016414984 0.13136231 5.49E-05 4.260740146 0.467522656 GYYSPYSVSGSGS(ph)TAGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 GYYS(0.001)PYSVS(0.001)GS(0.002)GS(0.642)T(0.355)AGS(1)R;GY(0.003)Y(0.003)S(0.209)PYS(0.113)VS(0.061)GS(0.012)GS(0.545)T(0.056)AGS(0.998)R ; 134.82 0.00064756 17444400 3933.4 3294.2 3823.4 4608.4 4285 5872.7 5145.1 5086.8 3941.8 3985.4 TRUE FALSE FALSE 3622.067239 3578.935969 3965.098567 4589.331662 4233.904174 4654.635821 5289.457659 6637.741903 3509.394402 4123.892353 0.878312751 0.867853878 0.961494197 1.112864078 1.026676695 1.128699642 1.28263718 1.609581758 0.850990788 1 12.00979096 -2.467754607 0.557018123 0.938125182 6.392047365 0.921568059 0.061722689 4.603268162 0.199273794 0.01252564 25.25101847 0.003406006 2.467754607 5.453922183 GYYSPYSVSGSGS(ph)TAGSR ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 GYYSPYSVSGS(0.026)GS(0.886)T(0.088)AGSR 210.02 1.37E-12 6543800 1289.3 1125.9 1430.5 1672.6 1664.2 2078 1600.9 1716.4 1398.1 1498.1 TRUE FALSE FALSE 1187.250545 1223.217779 1483.515588 1665.679224 1644.355502 1646.999376 1645.816945 2239.722459 1244.731928 1550.158863 0.765889595 0.789091885 0.957008745 1.074521627 1.060765797 1.062471347 1.061708567 1.444834147 0.802970558 1 10.59820036 -1 0.478594997 0.889412903 15.11080576 0.743303523 0.095427735 40.54284305 0.410472796 0.024118988 577.2469526 0.1 1 14.22139286 GYYSPYSVSGSGSTAGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 5 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 GYYSPYSVSGSGS(0.075)T(0.041)AGS(0.884)R;GYYSPYSVSGSGS(0.001)T(0.001)AGS(0.999)R;GYYSPYSVS(0.006)GS(0.076)GS(0.326)T(0.223)AGS(0.368)R;GYYSPYSVSGSGST(0.001)AGS(0.999)R;GYYSPYSVSGS(0.003)GS(0.21)T(0.019)AGS(0.768)R ;;;; 311.7 2.04E-113 1761204000 10332.18 7661.11 9309.46 9067.88 10010.6 12336.5 9021.59 9454.86 10533.43 8096.72 TRUE FALSE FALSE 9514.377051 8323.302211 9654.476777 9030.359515 9891.230133 9777.770839 9274.711535 12337.60329 9377.939082 8378.080417 1.135627325 0.993461724 1.1523495 1.077855435 1.180608163 1.167065766 1.107021068 1.472605021 1.119342214 1 13.03240402 -1 0.800375635 1.071954288 94.14322135 0.719669868 0.066893835 198.2971482 0.650388406 0.011472687 33486.82308 0.1 1 93.07126706 GYYSPYSVSGSGSTAGSR ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPYSVSGSGSTAGSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 185.2 8.31E-08 1413700 195.32 0 55.611 82.299 137.15 151.28 135.84 82.807 160.59 0 FALSE FALSE TRUE 179.8602159 0 57.67199258 81.95846854 135.5145758 119.9028227 139.6513048 108.0544731 142.9736788 0 0 QIDSS(ph)PVGGETDETTVSQNYR ddPTM_HeLa_Curcumin_4h_R1 2 QIDSSPVGGETDETTVSQNYR 21 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 QIDS(0.015)S(0.985)PVGGETDETTVSQNYR;QIDS(0.093)S(0.907)PVGGETDETTVSQNYR ; 332.57 5.11E-139 18733500 48904 41381 40697 44501 41444 47397 26908 13186.2 48124 39640 TRUE FALSE FALSE 45033.1968 44957.78925 42205.26662 44316.86665 40949.80737 37566.32793 27662.96606 17206.61168 42844.9176 41017.48705 1.097902383 1.096063959 1.028957883 1.080438365 0.99834998 0.915861274 0.674418841 0.419494536 1.044552475 1 15.32395149 -4.492454437 1.227767003 1.052521121 0.268504411 0.978882002 0.03036848 0.130439577 0.217435838 0.006240042 0.115843618 3.22E-05 4.492454437 -0.78401671 down HADNS(ph)SDTEMEDMIAEETLEEMDSELLK ddPTM_HeLa_Curcumin_4h_R1 1 HADNSSDTEMEDMIAEETLEEMDSELLK 28 0 E7EX82;Q8NDX5-2;Q8NDX5;Q8NDX5-7 E7EX82 PHC3 Polyhomeotic-like protein 3 1 0 HADNS(0.373)S(0.373)DT(0.254)EMEDMIAEETLEEMDSELLK 69.284 0.00018149 12465000 1009.5 735.89 767.73 858.17 891.96 894.26 944.33 429.63 1109.5 780.71 TRUE FALSE FALSE 929.5970098 799.4970525 796.1827492 854.6191199 881.3239596 708.7803956 970.8253583 560.6222092 987.7906258 807.8396144 1.150719763 0.989672997 0.985570322 1.057906922 1.090964028 0.877377617 1.201755077 0.69397712 1.222755864 1 9.657925084 -4.246203216 24.48682421 1.05540314 0.69397677 0.541661278 0.101853628 1131.124742 1817850.186 0.012220164 0.375843091 5.67E-05 4.246203216 -0.36142637 HAEATLGS(ph)GNLR ddPTM_HeLa_Curcumin_4h_R1 2 HAEATLGSGNLR 12 0 Q9H8S9-2;Q9H8S9;D6RCK3;Q7L9L4;Q7L9L4-2 Q9H8S9-2 MOB1A;MOB1B MOB kinase activator 1A;MOB kinase activator 1B 1 0 HAEAT(0.089)LGS(0.911)GNLR;HAEAT(0.062)LGS(0.938)GNLR ; 92.773 0.006304 30205000 4660.2 4669.1 4352 5052 4733.6 5752 4171.8 3254.5 5453.7 4672.3 TRUE FALSE FALSE 4291.340253 5072.676199 4513.288948 5031.096163 4677.154912 4558.970362 4288.84948 4246.782068 4855.442754 4834.662077 0.887619483 1.049230767 0.933527282 1.040630365 0.967421267 0.942976011 0.887104292 0.878403082 1.004298269 1 12.23919934 -4.806979654 3.135915431 0.96090243 0.879296298 0.345338206 0.048731419 0.269152469 5.279916553 0.007841953 0.030960791 1.56E-05 4.806979654 -0.081606132 HAEELAAQK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 HAEELAAQKR 10 1 O60563 O60563 CCNT1 Cyclin-T1 0 1 ; HAEELAAQK(1)R;HAEELAAQK(1)R 96.171 0.0031673 5410800 2620.52 2670.59 3186.4 2941.5 2240.77 2985.9 1345.29 1207.93 2847.43 2528.67 FALSE TRUE FALSE 2413.103077 2901.4239 3304.490787 2929.328852 2214.050281 2366.590682 1383.035217 1576.222296 2535.074053 2616.541094 0.922249256 1.108877635 1.262923328 1.11954246 0.846174473 0.904472965 0.528573856 0.602406857 0.968864605 1 11.3534452 -4.909990933 1.901878508 1.00418158 0.544361134 0.70902665 0.115848615 0.173923945 1.182624316 0.018723217 0.0897518 1.23E-05 4.909990933 -0.459820446 HAELSGS(ph)PLK ddPTM_HeLa_Curcumin_4h_R1 1 HAELSGSPLK 10 0 F6RRE2;E7EV10;Q9BTC8 F6RRE2 MTA3 Metastasis-associated protein MTA3 1 0 HAELS(0.006)GS(0.994)PLK 115.57 0.0014369 0 3883.1 2516.2 3128.3 3091.6 3287.5 3927.3 3181.6 2423.8 3591.7 2741.9 TRUE FALSE FALSE 3575.748538 2733.689116 3244.23755 3078.807778 3248.29871 3112.73371 3270.867133 3162.805462 3197.699496 2837.180821 1.260317464 0.963523049 1.143472255 1.085164455 1.144903661 1.097122075 1.152858186 1.114770493 1.127069333 1 11.47024238 -4.766865332 24.83877184 1.112952399 1.133814335 0.011526271 0.0779125 820.5023416 3756131.466 0.014295326 0.044790913 1.71E-05 4.766865332 0.020861936 HAEMVHTGLK(ac)LER ddPTM_HeLa_Curcumin_4h_R1 1 HAEMVHTGLKLER 13 1 Q01518-2;Q01518;Q5T0R7;Q5T0R6;Q5T0R5;Q5T0R4;Q5T0R3;Q5T0R2;Q5T0R1;Q5T0R9 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1;Adenylyl cyclase-associated protein 0 1 HAEMVHTGLK(1)LER 102.87 0.00065537 2879400 3135.2 3489.5 2848.9 5517.1 2996.4 2644.1 2381 1535.4 3004.2 2992 FALSE TRUE FALSE 2887.045612 3791.116831 2954.48274 5494.271702 2960.669887 2095.683855 2447.804452 2003.536392 2674.646776 3095.971777 0.932516773 1.224532103 0.95429899 1.77465174 0.956297441 0.67690664 0.79064172 0.647142977 0.863911873 1 11.5961766 -5.353354341 5.281206152 1.049317247 0.714800985 0.333062406 0.251326872 0.230923446 10.2415043 0.036275337 0.082840673 4.43E-06 5.353354341 -0.334516262 HALIIYDDLSK ddPTM_HeLa_Curcumin_4h_R1 1 HALIIYDDLSK 11 0 P25705;P25705-2;P25705-3 P25705 ATP5A1 "ATP synthase subunit alpha, mitochondrial" 0 0 79.693 0.012693 1419400 2053.9 1435.7 1978.5 1576.3 1949.7 3868.8 2393.3 1969.6 2212.9 1871.3 FALSE FALSE TRUE 1891.331648 1559.795511 2051.82495 1569.777688 1926.451101 3066.36727 2460.449557 2570.121973 1970.150406 1936.327536 0.976762254 0.805543216 1.059647664 0.810698427 0.994899399 1.583599475 1.270678391 1.327317784 1.017467536 1 10.91910729 -5.333572535 8.037460337 0.966215039 1.380896619 0.773712479 0.109244077 0.103210187 10.55015437 0.014477706 0.032494692 4.64E-06 5.333572535 0.414681581 HALIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 HALIKK 6 1 I3L0K7;Q12931-2;Q12931;I3L253 I3L0K7 TRAP1 "Heat shock protein 75 kDa, mitochondrial" 0 1 ; HALIK(1)K;HALIK(1)K 88.627 0.011428 14500900 15473.5 13504.5 15266.7 14200.4 15974.9 22741 16266.8 13951.9 16125 12989.2 FALSE TRUE FALSE 14248.75615 14671.76881 15832.49733 14141.64251 15784.40975 18024.26026 16723.20263 18205.77008 14356.12784 13440.57373 1.060130053 1.091602866 1.177962909 1.052160629 1.174385117 1.341033546 1.244232795 1.354538165 1.068118678 1 13.7143071 -4.145309142 0.28075901 0.997702344 1.668425857 0.783255646 0.054777471 2.501921151 0.141285356 0.026503567 0.584986324 7.16E-05 4.145309142 0.670723513 SPGAGSLGS(ph)PASQR ddPTM_HeLa_Curcumin_4h_R1 3 SPGAGSLGSPASQR 14 0 E9PC47;P53667-4;P53667-2;P53667 E9PC47 LIMK1 LIM domain kinase 1 1 0 SPGAGSLGS(0.999)PASQR;SPGAGSLGS(1)PASQR;SPGAGSLGS(1)PASQR ;; 247.11 3.79E-29 105813000 4884.3 3512.6 4362 3860.7 4579.4 4592.1 2484.76 838.77 4194.3 3667.1 TRUE FALSE FALSE 4497.702501 3816.213492 4523.659557 3844.725446 4524.793646 3639.646696 2554.475678 1094.507112 3734.195784 3794.531452 1.185311693 1.005714023 1.192152342 1.013227982 1.192451216 0.959182113 0.673199237 0.288443284 0.98409931 1 11.88970604 -4.489849641 1.649481152 1.092308372 0.183361901 0.904311678 0.081720326 0.134701483 0.484508288 0.012222997 0.168462758 3.24E-05 4.489849641 -0.908946471 down RAS(ph)PNLFSEAQYQEAPVEK ddPTM_HeLa_Curcumin_4h_R1 1 RASPNLFSEAQYQEAPVEK 19 1 Q9HC77;F6VUX8;Q9HC77-2 Q9HC77 CENPJ Centromere protein J 1 0 RAS(0.731)PNLFS(0.06)EAQY(0.208)QEAPVEK 57.238 0.012739 3325500 2321.5 1546.6 1990.1 2375.3 1912.9 1868.7 1267.3 463.56 2165.6 1692.6 TRUE FALSE FALSE 2137.750825 1680.281212 2063.854857 2365.471638 1890.089917 1481.110555 1302.857027 604.89731 1928.039098 1751.417724 1.220583072 0.959383469 1.178390985 1.350603917 1.079177109 0.845663793 0.743887086 0.345375807 1.100844802 1 10.7743075 -4.483921647 1.211942828 1.117747686 0.187779114 0.825258251 0.1134323 0.356177682 0.568522685 0.019403173 0.373221378 3.28E-05 4.483921647 -0.929968572 down HAPTYTIPLS(ph)PVLSPTLPAEAPTAQVPPSLPR ddPTM_HeLa_Curcumin_4h_R1 1 HAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPR 32 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 0 HAPT(0.002)YT(0.006)IPLS(0.702)PVLS(0.209)PT(0.08)LPAEAPTAQVPPSLPR 68.96 2.63E-05 40442000 960.18 801.93 800.81 798.73 889.07 941.47 518.75 422.83 1197.4 933.5 TRUE FALSE FALSE 884.1807398 871.2452559 830.4887231 795.4250669 878.4684209 746.1985094 533.3047289 551.7489205 1066.048216 965.9390555 0.915358722 0.901967107 0.859773418 0.823473347 0.909444976 0.772510962 0.552110121 0.571204692 1.10363921 1 9.915788357 -3.747873039 0.381617429 0.971180817 1.47E-14 0.833443208 0.067033653 1.950732064 0.146190215 0.015472663 0.939228072 0.000178701 3.747873039 -0.971180817 HAPTYTIPLSPVLS(ph)PTLPAEAPTAQVPPSLPR ddPTM_HeLa_Curcumin_4h_R1 1 HAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPR 32 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 0 HAPT(0.009)Y(0.005)T(0.008)IPLS(0.393)PVLS(0.473)PT(0.112)LPAEAPTAQVPPSLPR 52.669 0.0022808 35047000 1627.4 1270.3 1166.5 1202.4 1303.6 1229.8 892.79 486.55 1586 1176.1 TRUE FALSE FALSE 1498.589573 1380.099072 1209.731516 1197.424787 1288.055421 974.7256173 917.8392846 634.8968552 1412.019768 1216.969387 1.231411068 1.13404584 0.994052544 0.983939941 1.058412344 0.800945059 0.754200799 0.521703226 1.160275503 1 10.24907716 -4.448389539 0.687128366 1.107865479 0.263936404 0.867062738 0.074426693 0.797543821 0.303195209 0.01719929 0.496040387 3.56E-05 4.448389539 -0.843929075 SVGKVEPSS(ph)QSPGRS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SVGKVEPSSQSPGRSPR 17 2 X6RM00;G8JLD3;X6RLX0;Q8IUD2-5;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 2 0 SVGKVEPS(0.192)S(0.803)QS(0.005)PGRS(1)PR 227.09 1.29E-21 7050500 4039.5 3114.3 2209 3309.3 2273.6 3373.2 2441 654.17 5179.6 3622.2 TRUE FALSE FALSE 3719.769313 3383.486215 2290.867483 3295.606993 2246.488805 2673.560296 2509.48789 853.6234216 4611.410839 3748.07118 0.992448951 0.90272731 0.611212374 0.879280791 0.599371969 0.713316308 0.669541151 0.227750056 1.230342386 1 11.87193264 -4.482855532 0.321338707 1.026692957 8.28E-17 0.722101615 0.139865332 2.304910198 0.189843533 0.048877371 0.904637407 3.29E-05 4.482855532 -1.026692957 down EATQPEPIY(ph)AESTKR ddPTM_HeLa_Curcumin_4h_R1 2 EATQPEPIYAESTKR 15 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 0 EATQPEPIY(0.999)AESTKR;EATQPEPIY(1)AESTKR ; 160.63 0.00025701 94012000 4048.3 3205.4 3362 3108.5 3416.1 4038.1 2176.14 439.04 3939.5 4047.1 TRUE FALSE FALSE 3727.872783 3482.460493 3486.598678 3095.637851 3375.365239 3200.552541 2237.196632 572.9012749 3507.346706 4187.736424 0.890188017 0.831585406 0.832573573 0.739215065 0.806011863 0.764267905 0.53422575 0.136804521 0.837528046 1 12.03195493 -4.481357028 0.843789618 0.921584567 4.02E-68 0.865608402 0.084211868 0.474004812 0.302295307 0.015039518 0.375920064 3.30E-05 4.481357028 -0.921584567 down HAS(ph)APSHVQPSDSEKNR ddPTM_HeLa_Curcumin_4h_R1 2 HASAPSHVQPSDSEKNR 17 1 A0A3B3IRT3;O60343-2;O60343-3;O60343 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 1 0 HAS(0.725)APS(0.275)HVQPSDSEKNR;HAS(0.858)APS(0.142)HVQPSDSEKNR ; 69.261 0.0077111 8293800 4925.2 3088.7 2529.8 2780 2472.7 5969.5 2319.4 709.46 6803.2 5003.6 TRUE FALSE FALSE 4535.365223 3355.673465 2623.556613 2768.497097 2443.214667 4731.35841 2384.476122 925.771088 6056.905981 5177.474728 0.875980176 0.648129376 0.506725141 0.534719577 0.471893113 0.913835153 0.460548095 0.178807457 1.169857179 1 12.33803289 -7.242143363 1.561259014 0.955991399 0.522098192 0.603988974 0.181308675 0.198907463 0.922052722 0.032405588 0.038745084 5.73E-08 7.242143363 -0.433893207 HAS(ph)PILPITEFSDIPR ddPTM_HeLa_Curcumin_4h_R1 3 HASPILPITEFSDIPR 16 0 G5E972;P42167;H0YJH7 G5E972 TMPO "Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin" 1 0 HAS(1)PILPITEFSDIPR;HAS(1)PILPITEFSDIPR;HAS(0.999)PILPITEFSDIPR ;; 103.99 0.00098393 27148300 2097.81 2046.54 2179.18 2773.03 1913.16 2478.13 1267.01 702.63 3799.89 2020.16 TRUE FALSE FALSE 1931.766125 2223.433798 2259.942328 2761.555937 1890.346817 1964.137904 1302.558891 916.8586525 3383.051574 2090.36041 0.92413065 1.0636605 1.081125684 1.321090815 0.904316216 0.939616869 0.623126464 0.438612714 1.618405878 1 11.02953599 -4.644997837 1.970275008 1.003765617 0.421742195 0.480565479 0.224601474 0.164262185 1.086896026 0.017529959 0.130766383 2.26E-05 4.644997837 -0.582023422 RAS(ph)PPDPSPSPSAASASER ddPTM_HeLa_Curcumin_4h_R1 2 RASPPDPSPSPSAASASER 19 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 0 RAS(0.997)PPDPS(0.003)PSPSAASASER;RAS(1)PPDPSPSPSAASASER ; 130.95 7.39E-05 117471000 5488 4997.7 4652.8 4873.1 4457.4 4882.2 2648.1 887.55 5961.4 4751.1 TRUE FALSE FALSE 5053.619009 5429.678919 4825.236861 4852.936403 4404.248416 3869.576686 2722.398559 1158.159909 5307.449335 4916.200371 1.027952204 1.10444622 0.981497192 0.987131532 0.895864302 0.787107195 0.5537607 0.23558029 1.079583608 1 12.263328 -4.480078618 0.946301404 1.018882352 5.38E-19 0.977530755 0.03899365 0.13429851 0.113621841 0.005483457 0.128719558 3.31E-05 4.480078618 -1.018882352 down HASSS(ph)PES(ph)PKPAPAPGSHR ddPTM_HeLa_Curcumin_4h_R1 1 HASSSPESPKPAPAPGSHR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 HAS(0.277)S(0.331)S(0.396)PES(0.994)PKPAPAPGS(0.001)HR 62.325 0.0075511 4496900 1098.8 676.73 709.2 947.18 1066.9 1025.3 973.15 838.6 975.05 881.16 TRUE FALSE FALSE 1011.828821 735.2235257 735.4835759 943.2608201 1054.177914 812.6412225 1000.45397 1094.28528 868.0894545 911.7802444 1.109728826 0.806360447 0.806645659 1.034526495 1.156175428 0.891268732 1.097253396 1.200163402 0.952081886 1 9.83254234 -4.524049782 24.96865952 1.014694468 1.17443595 0.225714236 0.116688109 41.25117307 879592.6417 0.017225951 0.065553821 2.99E-05 4.524049782 0.159741483 HASSSPES(ph)PKPAPAPGSHR ddPTM_HeLa_Curcumin_4h_R1 1 HASSSPESPKPAPAPGSHR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 HAS(0.096)S(0.09)S(0.084)PES(0.729)PKPAPAPGS(0.001)HR 50.851 0.01568 6685300 2081.4 2073.1 1990.4 2279.6 2371.1 3160.7 1795.6 1691.5 2772.8 2069.8 TRUE FALSE FALSE 1916.654994 2252.289526 2064.165975 2270.167619 2342.826181 2505.135192 1845.979703 2207.230563 2468.630777 2141.725396 0.894911643 1.051623859 0.963786477 1.059971378 1.093896624 1.169680855 0.861912413 1.030585232 1.152636459 1 11.0645578 -7.244311373 24.08028631 0.950374941 1.03244686 0 0.101971987 668.7978277 940263.6978 0.013976956 0.017092885 5.70E-08 7.244311373 0.082071919 HCAPS(ph)PDRS(ph)PELSSSR ddPTM_HeLa_Curcumin_4h_R1 1 HCAPSPDRSPELSSSR 16 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 2 0 HCAPS(1)PDRS(0.962)PELS(0.016)S(0.012)S(0.01)R 94.188 0.0032189 203710000 2512.2 2221.5 2322.7 2424 2430.7 2544.6 2104.3 1717 2881.5 2352.9 TRUE FALSE FALSE 2313.356719 2413.516561 2408.781305 2413.97013 2401.71549 2016.821276 2163.340995 2240.505396 2565.406659 2434.6631 0.950175291 0.991314388 0.989369455 0.991500685 0.986467282 0.82837797 0.888558665 0.920252743 1.053700883 1 11.24950644 -5.278399742 24.87504346 0.979832603 0.880012681 0.69742061 0.033917829 272.8938143 400241.4491 0.003954801 0.008865599 5.27E-06 5.278399742 -0.099819922 HCAPS(ph)PDRSPELS(ph)SSR ddPTM_HeLa_Curcumin_4h_R1 1 HCAPSPDRSPELSSSR 16 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 2 0 HCAPS(0.999)PDRS(0.093)PELS(0.503)S(0.36)S(0.045)R 119.51 0.0038711 22047000 2396.9 2368.8 2035.5 1951 2161.4 2786.6 1836.8 1793.3 2650.5 2314.7 TRUE FALSE FALSE 2207.182836 2573.548517 2110.937421 1942.927279 2135.626717 2208.627749 1888.335665 2340.068915 2359.746781 2395.135653 0.921527277 1.07448967 0.881343576 0.811197177 0.891651675 0.922130547 0.788404474 0.977008927 0.98522469 1 11.22589165 -6.564681485 24.99949347 0.970637981 0.873295195 0.437093503 0.062300019 113.6764166 67982.04906 0.009563057 0.013524212 2.72E-07 6.564681485 -0.097342786 HCAPS(ph)PDRSPELSSSR ddPTM_HeLa_Curcumin_4h_R1 2 HCAPSPDRSPELSSSR 16 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 0 HCAPS(0.886)PDRS(0.008)PELS(0.035)S(0.035)S(0.035)R;HCAPS(0.998)PDRS(0.001)PELSSSR ; 76.068 0.0073804 17298000 2252.9 1880.93 1787.23 2223.02 1553.1 2292.74 2067.45 2165.21 2232.4 2157.6 TRUE FALSE FALSE 2074.580588 2043.509208 1853.466316 2213.821732 1534.580297 1817.199879 2125.457083 2825.372562 1987.511305 2232.576439 0.929231605 0.91531433 0.830191649 0.991599523 0.687358457 0.813947441 0.952019848 1.265521087 0.890232142 1 11.12449386 -8.568404784 0.846549679 0.993917925 0.911321756 0 0.145105966 1.436536381 2.101920439 0.060886476 0.03003002 2.70E-09 8.568404784 -0.082596169 HCQENK(ac)CPVPFCLNIK ddPTM_HeLa_Curcumin_4h_R1 2 HCQENKCPVPFCLNIK 16 1 A0A669KB12;Q09472;Q92793;Q92793-2 A0A669KB12;Q92793 EP300;CREBBP Histone acetyltransferase p300;CREB-binding protein 0 1 ; HCQENK(1)CPVPFCLNIK;HCQENK(1)CPVPFCLNIK 170.74 0.00022707 7149000 4692.8 3779.2 3913.7 4080.7 3652.4 5860.4 3444.99 2852.58 5132 4641 FALSE TRUE FALSE 4321.359928 4105.857208 4058.745165 4063.815145 3608.847515 4644.88698 3541.647148 3722.31851 4569.03244 4802.274405 0.899856935 0.854981799 0.845171438 0.846227184 0.751487152 0.967226482 0.737493706 0.775115747 0.951430938 1 12.22950213 -8.871631687 0.126781461 1.195433862 0.6887744 0.510087893 0.060771557 7.783156863 0.340462812 0.939235474 0.419083875 1.34E-09 8.871631687 -0.506659462 HDADGQATLLNLLLR ddPTM_HeLa_Curcumin_4h_R1 1 HDADGQATLLNLLLR 15 0 O43242;O43242-2 O43242 PSMD3 26S proteasome non-ATPase regulatory subunit 3 0 0 110.22 0.0017618 4421400 2203.1 1697.6 1676.9 1655 1690.8 3182.2 1951.8 2208 1945.5 2041.9 FALSE FALSE TRUE 2028.72231 1844.33298 1739.047389 1648.152049 1670.638314 2522.175849 2006.562255 2881.209036 1732.083517 2112.855873 0.96018017 0.872909981 0.823079043 0.78005891 0.790701503 1.1937283 0.949691969 1.363656212 0.819783091 1 11.04497864 HDGGS(ph)PSIK ddPTM_HeLa_Curcumin_4h_R1 1 HDGGSPSIK 9 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 0 HDGGS(0.998)PS(0.002)IK 83.226 0.013353 14010000 8268.7 14881 6752 5874.6 5280.6 7770.4 6345.1 2361.2 5181.6 7336.7 TRUE FALSE FALSE 7614.22367 16167.24733 7002.23506 5850.292462 5217.632294 6158.73145 6523.126429 3081.11901 4613.191444 7591.649779 1.002973516 2.129609216 0.922360128 0.770622017 0.687285695 0.811250733 0.859250179 0.405856316 0.607666525 1 12.89019772 -6.387653361 4.736906517 1.103158675 0.722190469 0.242255528 0.382451833 0.288187621 9.944791711 0.055923324 0.086180327 4.10E-07 6.387653361 -0.380968206 HDS(ph)PDLAPNVTYSLPR ddPTM_HeLa_Curcumin_4h_R1 4 HDSPDLAPNVTYSLPR 16 0 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 0 HDS(1)PDLAPNVTYSLPR;HDS(1)PDLAPNVTYSLPR;HDS(1)PDLAPNVTYSLPR;HDS(1)PDLAPNVTYSLPR ;;; 99.711 0.0029837 67980300 8569.9 7297.4 8344.2 7904.8 8627.6 10821.6 8327.6 5574.3 10176.3 8152.4 TRUE FALSE FALSE 7891.583372 7928.154739 8653.443392 7872.092032 8524.721505 8577.078175 8561.250043 7273.878409 9059.98535 8435.695293 0.935498865 0.939834177 1.025812703 0.933188286 1.010553512 1.016760075 1.014883746 0.862273726 1.074005762 1 13.04229127 -4.248837051 24.12267215 0.97647043 0.862273607 0.371659007 0.046536187 904.8598375 1731981.725 0.005310059 0.121978311 5.64E-05 4.248837051 -0.114196823 HDS(ph)PEDVK ddPTM_HeLa_Curcumin_4h_R1 1 HDSPEDVK 8 0 P31948;P31948-2;P31948-3;H0YGI8 P31948 STIP1 Stress-induced-phosphoprotein 1 1 0 HDS(1)PEDVK 90.149 0.0099456 70876000 8399.9 14771 7203.5 6887.2 6124.2 7417.4 5691.7 4943.9 5228.5 6499.1 TRUE FALSE FALSE 7735.039051 16047.73942 7470.468047 6858.702591 6051.172915 5878.947629 5851.393784 6451.272351 4654.946631 6724.943241 1.150201388 2.386301095 1.110859643 1.019890034 0.899810258 0.874200334 0.870103074 0.9593051 0.692191215 1 12.71530638 -6.102881307 3.21891581 1.193996652 0.901790706 0.13921117 0.41528244 0.49392605 9.733210003 0.063560053 0.111424199 7.89E-07 6.102881307 -0.292205946 QSPGTSMTPSSGSFPSAYDQQS(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 QSPGTSMTPSSGSFPSAYDQQSSK 24 0 P46020-3;P46020-2 P46020-3 1 0 QSPGTSMTPSSGSFPS(0.042)AY(0.038)DQQS(0.46)S(0.46)K 51.966 0.0082922 70594000 344.46 493.18 384.32 545.86 400.4 429.96 636.65 2489.9 533.9 458.16 TRUE FALSE FALSE 317.1956275 535.8082816 398.5632373 543.601376 395.6254915 340.7814494 654.5126855 3249.059048 475.3325058 474.0810259 0.669074716 1.130204021 0.840707001 1.146642338 0.834510284 0.718825329 1.380592451 6.853383431 1.002639802 1 8.888989843 -4.260188219 4.031287776 0.878161979 7.388021163 0.992368505 0.155235016 0.014643912 0.498443937 0.023737275 0.277462404 5.49E-05 4.260188219 6.509859185 up HDSIPAADTFEDLS(ph)DVEGGGSEPTQR ddPTM_HeLa_Curcumin_4h_R1 3 HDSIPAADTFEDLSDVEGGGSEPTQR 26 0 O95671;O95671-2;O95671-3 O95671 ASMTL N-acetylserotonin O-methyltransferase-like protein 1 0 HDSIPAADTFEDLS(0.997)DVEGGGS(0.003)EPT(0.001)QR;HDSIPAADT(0.006)FEDLS(0.992)DVEGGGS(0.002)EPTQR;HDSIPAADT(0.003)FEDLS(0.991)DVEGGGS(0.003)EPT(0.002)QR ;; 97.352 2.83E-06 13557400 5548.4 4691.4 5265.5 5680 5214.5 6952.5 4660.9 3874.3 5893.9 4864.9 TRUE FALSE FALSE 5109.238285 5096.903712 5460.644062 5656.497665 5152.320493 5510.473129 4791.67231 5055.556235 5247.353916 5033.954913 1.014955115 1.01250484 1.084762211 1.123668718 1.023513437 1.094660803 0.951870327 1.004291123 1.042391918 1 12.29747658 -1.891225759 15.04883837 1.022593543 0.415177293 0 0.050670498 0 0 0.006911321 0 0.012846187 1.891225759 -0.60741625 HDYWLLAGIVLHGYAR ddPTM_HeLa_Curcumin_4h_R1 1 HDYWLLAGIVLHGYAR 16 0 Q12873-2;Q12873;Q12873-3;I3L229;H7C3H7;H7C0J3 Q12873-2 CHD3 Chromodomain-helicase-DNA-binding protein 3 0 0 48.112 0.018554 4764900 2896.9 2037.1 1752.8 2556.1 1225 2780 2301.4 2270.3 3441 2707.6 FALSE FALSE TRUE 2667.607308 2213.177847 1817.76031 2545.523535 1210.392675 2203.396663 2365.97109 2962.504019 3063.530909 2801.688898 0.952142584 0.789944183 0.648808763 0.90856752 0.432022512 0.786453008 0.844480303 1.05739935 1.093458632 1 11.45208105 -7.281294063 3.676365568 0.979293947 0.76874383 0.307722017 0.158193572 0.221846487 6.438147504 0.026192733 0.030703408 5.23E-08 7.281294063 -0.210550116 HEAMITDLEER ddPTM_HeLa_Curcumin_4h_R1 2 HEAMITDLEER 11 0 P35579 P35579 MYH9 Myosin-9 0 0 ; ; 168.85 0.00019805 54273000 18792.2 16047.5 17352.6 17147.7 18989.1 19356.2 16687 14527.5 17936.8 16926.3 FALSE FALSE TRUE 17304.77754 17434.57439 17995.70262 17076.74736 18762.66738 15341.50593 17155.19231 18956.86787 15969.17792 17514.48767 0.988026477 0.995437305 1.027475252 0.975006959 1.071265557 0.875932327 0.97948582 1.082353548 0.911769629 1 14.09626117 -4.256470291 23.7469136 0.991723393 1.082353627 0.227015874 0.052849302 258.9810705 1237563.356 0.005844339 0.063043145 5.54E-05 4.256470291 0.090630233 HEAPS(ph)SPISGQPCGDDQNAS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 HEAPSSPISGQPCGDDQNASPSK 23 0 A0A088AWL3;O75376-2;O75376;E7EVU5;E7EW50;J3KS51;O75376-3 A0A088AWL3 NCOR1 Nuclear receptor corepressor 1 2 0 HEAPS(0.498)S(0.498)PIS(0.005)GQPCGDDQNAS(0.827)PS(0.173)K 120.8 1.07E-05 14022000 3763.9 3408.3 3010.6 3429.3 4301.3 3687.6 3202.9 1310.2 3028.9 2587 TRUE FALSE FALSE 3465.983343 3702.898265 3122.175484 3415.110465 4250.009807 2922.750192 3292.764754 1709.673949 2696.637248 2676.898057 1.294775994 1.383279522 1.166340823 1.27577158 1.58766218 1.091842173 1.230067295 0.638677272 1.007373904 1 11.38634648 -4.259551167 24.42998076 1.200262587 0.638677013 0.51294824 0.170092089 86.62650354 1120660.577 0.025524214 0.220816307 5.50E-05 4.259551167 -0.561585574 HEAPS(ph)SPISGQPCGDDQNASPSK ddPTM_HeLa_Curcumin_4h_R1 1 HEAPSSPISGQPCGDDQNASPSK 23 0 A0A088AWL3;O75376-2;O75376;E7EVU5;E7EW50;J3KS51;O75376-3 A0A088AWL3 NCOR1 Nuclear receptor corepressor 1 1 0 HEAPS(0.512)S(0.487)PISGQPCGDDQNASPSK 135.84 6.22E-06 34577000 7247 6309.5 6359.3 6239 7711.7 9474.7 6738.7 2952.2 7227 6020.2 TRUE FALSE FALSE 6673.392303 6854.865065 6594.981252 6213.184671 7619.743014 7509.540418 6927.769786 3852.31219 6434.216181 6229.401502 1.071273428 1.100405081 1.058686176 0.997396727 1.223190223 1.205499504 1.112108408 0.618408075 1.032878709 1 12.60487785 -4.257811749 24.75378602 1.065999299 0.618407878 0.771217644 0.07597342 129.7404922 885262.618 0.011898689 0.118063341 5.52E-05 4.257811749 -0.447591421 HEAPSS(ph)PISGQPCGDDQNASPSK ddPTM_HeLa_Curcumin_4h_R1 1 HEAPSSPISGQPCGDDQNASPSK 23 0 A0A088AWL3;O75376-2;O75376;E7EVU5;E7EW50;J3KS51;O75376-3 A0A088AWL3 NCOR1 Nuclear receptor corepressor 1 1 0 HEAPS(0.23)S(0.767)PIS(0.002)GQPCGDDQNASPSK 102.06 1.83E-05 27213000 10403 8289.2 8596.2 8777.7 10898 13258 9801.5 4204.8 10294 7614.5 TRUE FALSE FALSE 9579.591573 9005.681512 8914.782734 8741.380203 10768.04847 10508.14135 10076.50371 5486.824163 9164.773954 7879.103308 1.215822562 1.142983048 1.131446357 1.109438455 1.366659129 1.333672239 1.278889655 0.696376726 1.163174742 1 12.94381574 -9.36434533 0.923367509 0.992366645 1.176219701 0 0.183213793 1.101211785 1.565836298 0.143970561 0.031694066 4.32E-10 9.36434533 0.183853056 HECQANGPEDLNR ddPTM_HeLa_Curcumin_4h_R1 4 HECQANGPEDLNR 13 0 P60981;P60981-2 P60981 DSTN Destrin 0 0 ;;; ;;; 137.62 0.00021732 32116300 5382.62 4896.8 4994.19 5246.67 5812.71 6427.43 5382 4164.34 5465.13 5669.08 FALSE FALSE TRUE 4956.579947 5320.057572 5179.279075 5224.96067 5743.39723 5094.308566 5533.004435 5434.028096 4865.618912 5866.080108 0.844956062 0.90691867 0.882919936 0.89070735 0.979086055 0.868434879 0.943220061 0.926347407 0.82944979 1 12.51818106 -9.55391402 1.338868041 0.99972641 0.898827047 0 0.063870443 0.302072604 0.974367548 0.027286105 0.006523333 2.79E-10 9.55391402 -0.100899362 TGS(ph)TSSKEDDYESDAATIVQK ddPTM_HeLa_Curcumin_4h_R1 1 TGSTSSKEDDYESDAATIVQK 21 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 0 T(0.151)GS(0.485)T(0.157)S(0.098)S(0.098)KEDDY(0.011)ESDAATIVQK 65.278 0.0022743 65040000 1673.7 1362 1790.6 1612.1 2014.9 2137.3 2260 3923.3 1677.1 2178 TRUE FALSE FALSE 1541.224879 1479.725211 1856.961211 1605.429557 1990.873633 1693.999888 2323.409518 5119.496109 1493.126326 2253.685338 0.683868707 0.656580218 0.823966496 0.712357458 0.883385804 0.751657678 1.03093785 2.271610869 0.66252653 1 11.13807038 -4.260182009 3.161092275 0.819696423 2.490125738 0.941467306 0.111167904 0.071334771 1.090180888 0.018919165 0.294153513 5.49E-05 4.260182009 1.670429315 up HEDEQALLDQNSQT(ph)PPPSPFSVQAFNK ddPTM_HeLa_Curcumin_4h_R1 2 HEDEQALLDQNSQTPPPSPFSVQAFNK 27 0 A0A499FJI4;O75592-2;O75592;A0A087WY34 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 0 HEDEQALLDQNS(0.083)QT(0.917)PPPSPFSVQAFNK;HEDEQALLDQNS(0.19)QT(0.81)PPPSPFSVQAFNK ; 103.59 1.28E-07 44184000 4094.3 3712.1 4081.5 3602.2 3668.7 5467 4285.3 2339.48 5174.5 4741.8 TRUE FALSE FALSE 3770.231835 4032.957383 4232.76398 3587.295051 3624.953149 4333.082574 4405.533985 3052.776682 4606.870296 4906.577197 0.768403652 0.821949237 0.862671433 0.73111966 0.738794684 0.883117171 0.897883353 0.622180506 0.938917317 1 12.26050124 -9.329713573 0.748840947 1.020069831 0.793830456 0.433468751 0.080463627 0.56435488 0.485561271 0.081070354 0.0153202 4.68E-10 9.329713573 -0.226239375 HEDGTQS(ph)DSEDPLAK ddPTM_HeLa_Curcumin_4h_R1 2 HEDGTQSDSEDPLAK 15 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 0 HEDGTQS(1)DSEDPLAK;HEDGTQS(0.997)DS(0.002)EDPLAK ; 173.34 5.93E-05 27033000 11300.2 10089.7 10674.2 10414.2 11527.4 13255 9978.9 4463.9 11580.8 9841.1 TRUE FALSE FALSE 10405.77725 10961.80871 11069.79524 10371.1088 11389.94328 10505.76359 10258.88108 5824.922561 10310.41521 10183.07749 1.021869592 1.076473072 1.08707758 1.018465077 1.118516803 1.031688465 1.007444074 0.57201986 1.012504837 1 13.31388601 -4.260795084 4.910879899 1.029926795 0.548000625 0.930874915 0.038316243 0.035416507 2.546170001 0.00594384 0.057925763 5.49E-05 4.260795084 -0.48192617 HEDLVPPAGS(ph)PELS(ph)PPQPLFRPR ddPTM_HeLa_Curcumin_4h_R1 1 HEDLVPPAGSPELSPPQPLFRPR 23 1 A0A0A0MQV9;Q9UPS6-2;Q9UPS6 A0A0A0MQV9 SETD1B Histone-lysine N-methyltransferase;Histone-lysine N-methyltransferase SETD1B 2 0 HEDLVPPAGS(1)PELS(1)PPQPLFRPR 73.76 0.00089271 5820200 2168.4 1811.1 1861.7 1538.1 1780.6 1670.9 1624.2 1239.7 1998.3 1683 TRUE FALSE FALSE 1996.768852 1967.643414 1930.69624 1531.73575 1759.367508 1324.336505 1669.770681 1617.678823 1779.09149 1741.484125 1.146590327 1.129865835 1.108649922 0.879557688 1.010269048 0.7604643 0.958820501 0.928908165 1.021595009 1 10.76610161 -6.261227015 24.99999778 1.079182706 0.907978493 0.584516489 0.073226792 11.98689359 1411092.071 0.012310157 0.019611719 5.48E-07 6.261227015 -0.171204212 HEEAPGHRPTTNPNASK ddPTM_HeLa_Curcumin_4h_R1 1 HEEAPGHRPTTNPNASK 17 1 E9PP21;P21291;E9PND2;E9PS42 E9PP21 CSRP1 Cysteine and glycine-rich protein 1 0 0 45.438 0.015353 6937600 1253.6 1157.7 1221.6 1294 1747.3 1744.1 1209.1 1214.4 1533.5 1312.2 FALSE FALSE TRUE 1154.376237 1257.766429 1266.873571 1288.645771 1726.464589 1382.354 1243.024092 1584.66497 1365.278887 1357.798852 0.850182069 0.92632751 0.933034793 0.949069716 1.271517195 1.018084525 0.915469983 1.167083745 1.005508941 1 10.40705406 -5.968311922 24.99968558 0.92803899 1.079413056 0.357476913 0.096176004 169.684221 133868.3133 0.014610933 0.026484422 1.08E-06 5.968311922 0.151374066 HEEEEWT(ph)DDDLVESL ddPTM_HeLa_Curcumin_4h_R1 1 HEEEEWTDDDLVESL 15 0 D6RHI7;P51946 D6RHI7 CCNH Cyclin-H 1 0 HEEEEWT(1)DDDLVESL 94.122 0.017326 39819000 2439.3 2071.6 2150.4 2300.5 2345.3 2960 1920.6 1994.8 2440.2 1982.1 TRUE FALSE FALSE 2246.226831 2250.659873 2230.095716 2290.981141 2317.333829 2346.062634 1974.486867 2603.005337 2172.516165 2050.977827 1.095198008 1.097359437 1.087332923 1.11701897 1.129867811 1.143875181 0.962705126 1.269153329 1.059258728 1 11.00209618 -13.52286328 0.166724833 0.550604621 1.138999497 0.177269828 0.071578231 53.9099612 0.590940651 7.825038112 0.107541574 3.00E-14 13.52286328 0.588394876 HEEEFDLFMR ddPTM_HeLa_Curcumin_4h_R1 1 HEEEFDLFMR 10 0 P51532;P51532-4;P51532-3;P51532-2;P51532-5;A0A0A0MT49;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8Y440;A0A2R8Y4C5;A0A2R8Y6N0;A0A2R8YG32;A0A2R8Y7F3;A0A2R8YF80;A0A2R8YF58;A0A2R8Y526;A0A2R8Y7Y7;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5 P51532 SMARCA4 Transcription activator BRG1 0 0 200.71 1.11E-06 2389300 1100.4 831.66 1036.9 1042.5 967.99 1051.5 1046.2 661.34 1272 1087.1 FALSE FALSE TRUE 1013.302179 903.5449846 1075.328426 1038.186411 956.4473515 833.4070472 1075.553556 862.9795216 1132.464782 1124.876644 0.900811822 0.803239172 0.95595231 0.922933565 0.850268655 0.740887502 0.956152447 0.767177029 1.006745751 1 10.13555109 -13.52287874 0.099499022 1.481105413 0.758463325 0.441231933 0.067723243 86.45013069 0.642500607 8.554090288 0.574924598 3.00E-14 13.52287874 -0.722642088 HEEQPAPGYDTHGR ddPTM_HeLa_Curcumin_4h_R1 2 HEEQPAPGYDTHGR 14 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 0 0 ; ; 85.536 0.004343 2952070 1445.99 1202.49 1535.83 1342.558 1278.9 1768.09 1031.7 1125.31 1206.89 1399.31 FALSE FALSE TRUE 1331.538366 1306.427877 1592.749211 1337.002851 1263.649953 1401.368204 1060.646725 1468.411839 1074.497186 1447.935918 0.919611392 0.902269127 1.100013606 0.923385375 0.872725054 0.967838553 0.73252325 1.014141455 0.742088909 1 10.49978204 -6.005323031 24.76810209 0.96707655 0.891134808 0 0.110607071 298.3151538 1388075.317 0.011877515 0.021083935 9.88E-07 6.005323031 -0.075941742 HEERQDEHGYISR ddPTM_HeLa_Curcumin_4h_R1 5 HEERQDEHGYISR 13 1 P04792 P04792 HSPB1 Heat shock protein beta-1 0 0 ;;;; ;;;; 116.71 0.0012977 38028350 5539.85 3942.31 3707.63 4563.81 3507.88 6118.34 4049.47 3815.82 7509.1 6069.08 FALSE FALSE TRUE 5101.365027 4283.06571 3845.038029 4544.926163 3466.050822 4849.327316 4163.08723 4979.245952 6685.370517 6279.980078 0.812321849 0.682018996 0.612269144 0.723716653 0.551920672 0.772188328 0.662914082 0.792876074 1.064552822 1 12.61654427 -8.04204463 0.769104012 0.974556911 0.679057708 0.742354715 0.077928322 0.201066576 0.260268437 0.024835699 0.017469993 9.08E-09 8.04204463 -0.295499203 HEHPPNPPVS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 1 HEHPPNPPVSPGK 13 0 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 0 HEHPPNPPVS(1)PGK 82.349 0.0093718 4571000 3128.1 2761.5 2762.4 3043.8 3148.2 2983.8 2859.9 2029.1 2831.3 2486.9 TRUE FALSE FALSE 2880.507584 3000.191755 2864.776974 3031.205562 3110.659771 2364.926246 2940.141097 2647.763249 2520.713474 2573.31959 1.11937421 1.165883852 1.113261246 1.177935914 1.208812066 0.919017698 1.142547979 1.028929038 0.9795571 1 11.32941493 -9.126030995 0.932880324 1.001355575 1.111231423 0.26072516 0.079193776 0.669780723 1.070414668 0.047830792 0.014627594 7.48E-10 9.126030995 0.109875848 HELIEFR ddPTM_HeLa_Curcumin_4h_R1 2 HELIEFR 7 0 A0A087WVQ6;Q00610-2;Q00610;J3KS13;K7EJJ5;J3KRF5 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 ; ; 187.63 0.00095796 21114000 12012.9 10134.6 11099.7 10425.7 12023.6 10627.8 9237.6 7520 8895.4 9124.4 FALSE FALSE TRUE 11062.06629 11010.58967 11511.06465 10382.56122 11880.22642 8423.47448 9496.782194 9812.813382 7919.596875 9441.472221 1.171646331 1.166194149 1.2192023 1.099676086 1.258302322 0.892178072 1.005858194 1.039330854 0.83880953 1 13.20479612 -5.245049519 24.98807011 1.111631371 0.981795967 0.199663619 0.117736849 865.2158315 1319110.871 0.013788639 0.03505376 5.69E-06 5.245049519 -0.129835404 HELLQPFNVLYEK ddPTM_HeLa_Curcumin_4h_R1 2 HELLQPFNVLYEK 13 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 0 ; ; 108.66 0.0034606 24717000 7765.8 6318.6 7410 6723.3 6770.4 10834 7834.2 8029.8 8010 7042.3 FALSE FALSE TRUE 7151.128736 6864.751629 7684.621118 6695.480766 6689.667402 8586.906276 8054.006567 10478.04906 7131.32304 7287.019401 0.981351681 0.942052059 1.054563011 0.918822964 0.918025194 1.178383891 1.105253894 1.437906019 0.978633739 1 12.83111312 -3.526260952 0.896196518 0.984242238 2.615275662 0.827927378 0.062716627 1.871170344 0.437196863 0.009081315 4.104949292 0.000297673 3.526260952 1.631033423 HELQANCYEEVK(ac)DR ddPTM_HeLa_Curcumin_4h_R1 2 HELQANCYEEVKDR 14 1 P23528;G3V1A4;E9PP50;E9PK25 P23528 CFL1 Cofilin-1 0 1 ; HELQANCYEEVK(1)DR;HELQANCYEEVK(1)DR 177.88 1.19E-07 55784000 3581.7 4821.2 3620 3712.2 7414.9 7609.3 6018.3 4624.7 6737.8 3492.3 FALSE TRUE FALSE 3298.204666 5237.923045 3754.160384 3696.8399 7326.48216 6031.045406 6187.157301 6034.74974 5998.680197 3613.657165 0.912705471 1.449479795 1.03888117 1.023018989 2.027442512 1.668958933 1.71215946 1.669984026 1.660002574 1 11.81924393 -5.775293592 24.89859921 1.0093999 1.758339472 0.477490858 0.267916351 67.4585275 121235.5301 0.026337857 0.047919641 1.68E-06 5.775293592 0.748939572 HELQANCYEEVKDR ddPTM_HeLa_Curcumin_4h_R1 2 HELQANCYEEVKDR 14 1 P23528;G3V1A4;E9PP50;E9PK25 P23528 CFL1 Cofilin-1 0 0 ; ; 72.705 0.0067851 105379000 30573.4 26272.7 28986.3 29176 30498.1 33531.4 28524.4 23204.9 26907.6 24910.9 FALSE FALSE TRUE 28153.48313 28543.59512 30060.55778 29055.27744 30134.43008 26576.60966 29324.71789 30279.96719 23955.9036 25776.55192 1.092212923 1.107347298 1.166197786 1.127197987 1.169063658 1.031038199 1.137650916 1.174709763 0.929368042 1 14.65377167 -8.468035236 0.552412227 0.997136938 1.132609746 0.645101808 0.046318464 0.439819268 0.278346507 0.027564397 0.011157824 3.40E-09 8.468035236 0.135472808 HEQNIDCGGGYVK ddPTM_HeLa_Curcumin_4h_R1 2 HEQNIDCGGGYVK 13 0 P27797 P27797 CALR Calreticulin 0 0 ; ; 106.13 0.00089956 22132000 7361.4 6579 8027.7 7290.6 8030.7 11805.8 8380.9 7458.1 8273.2 7548.7 FALSE FALSE TRUE 6778.737422 7147.659445 8325.213624 7260.433429 7934.939148 9357.144001 8616.045498 9732.040357 7365.650659 7811.016763 0.867843154 0.91507414 1.065829696 0.929511951 1.015865077 1.197941867 1.103063245 1.245937712 0.942982314 1 12.93129464 -5.410842951 2.995844588 0.944527024 1.176088948 0.740721057 0.060184678 0.113706191 1.943906816 0.010149116 0.024754715 3.88E-06 5.410842951 0.231561924 HERPAGPGT(ph)PPPDSGPLAK ddPTM_HeLa_Curcumin_4h_R1 1 HERPAGPGTPPPDSGPLAK 19 1 H0YME5;Q9P2K8-2;Q9P2K8 H0YME5 EIF2AK4 Eukaryotic translation initiation factor 2-alpha kinase 4 1 0 HERPAGPGT(0.989)PPPDS(0.011)GPLAK 52.273 0.012823 19428000 3266.6 2827 3236.7 2955 2998 3034.2 2628.1 2342.1 2670.9 2550 TRUE FALSE FALSE 3008.045163 3071.353283 3356.654949 2942.772993 2962.250808 2404.872718 2701.837413 3056.195508 2377.908952 2638.61231 1.140010282 1.164003242 1.27212889 1.115272972 1.122654812 0.911415712 1.023961498 1.158258641 0.901196793 1 11.36556368 -4.220308766 21.35193893 1.082232876 1.158260053 0.045482743 0.109964116 9844.313556 5109715.612 0.014598785 4.62577295 6.02E-05 4.220308766 0.076027177 HFDPEFTEEPVPNSIGKS(ph)PDSVLVTASVK ddPTM_HeLa_Curcumin_4h_R1 1 HFDPEFTEEPVPNSIGKSPDSVLVTASVK 29 1 E9PR89;O00141-4;O00141;O00141-3;O00141-5;O00141-2 E9PR89 SGK1 Serine/threonine-protein kinase Sgk1 1 0 HFDPEFTEEPVPNS(0.203)IGKS(0.739)PDS(0.056)VLVT(0.002)ASVK 104.38 1.50E-10 27530000 1750.4 1239.3 1712.3 1647.4 1430 2155.2 837.34 746.96 1695.9 1667.3 TRUE FALSE FALSE 1611.853993 1346.41957 1775.759344 1640.583495 1412.948184 1708.187226 860.8335068 974.7046654 1509.864013 1725.238551 0.93427891 0.780425159 1.029283367 0.950931391 0.818987138 0.990116541 0.498964915 0.564968053 0.875162459 1 10.75258014 -4.76070527 24.9999996 0.948319266 0.53196635 0.789431451 0.079763697 5.243234728 178520.2273 0.010751644 0.035989557 1.73E-05 4.76070527 -0.416352916 HFFHEDEEPFNPDYVEVDR ddPTM_HeLa_Curcumin_4h_R1 1 HFFHEDEEPFNPDYVEVDR 19 0 Q9HCK8-2;Q9HCK8;A0A2R8Y840;A0A2R8Y4P3 Q9HCK8-2 CHD8 Chromodomain-helicase-DNA-binding protein 8 0 0 75.143 0.0020377 4785300 811.78 525.5 526.82 633.99 696.6 795.58 749.23 303.23 662.57 604.29 FALSE FALSE TRUE 747.5267564 570.9218784 546.3444126 631.3667174 688.2935 630.56774 770.2513774 395.6834311 589.8877287 625.2890325 1.195489954 0.913052762 0.873746994 1.009719801 1.100760551 1.008442028 1.23183254 0.63280085 0.943384096 1 9.288379403 -7.250286045 24.91270099 1.092314702 0.982137252 0.019851526 0.160554188 1261.337827 2817394.698 0.025567237 0.031151826 5.62E-08 7.250286045 -0.11017745 HFFHHADEDDEEEDDS(ph)PPER ddPTM_HeLa_Curcumin_4h_R1 2 HFFHHADEDDEEEDDSPPER 20 0 A0A087WZV0;O43314-2;O43314;D6RFG4 A0A087WZV0 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 1 0 HFFHHADEDDEEEDDS(1)PPER;HFFHHADEDDEEEDDS(1)PPER ; 81.884 0.00087645 33645000 3618.3 3323.5 3313.3 4209.9 3943.7 3639.6 3366.7 2928.8 3820.5 3986.4 TRUE FALSE FALSE 3331.907737 3610.768531 3436.093813 4192.480549 3896.673953 2884.705933 3461.160541 3821.777637 3401.400708 4124.927103 0.807749483 0.875353295 0.83300716 1.016376882 0.944664925 0.699335009 0.83908405 0.926507922 0.824596562 1 12.01015291 -9.463765353 1.176504319 1.000680217 0.861837044 0 0.097130318 0.526066785 1.292434384 0.059672701 0.014438157 3.44E-10 9.463765353 -0.138843172 HFFLYGEFPGDER ddPTM_HeLa_Curcumin_4h_R1 1 HFFLYGEFPGDER 13 0 F5H8D7;P18887 F5H8D7 XRCC1 DNA repair protein XRCC1 0 0 88.101 0.011401 11826000 1367.6 1482.6 1458.1 1577.4 1113.3 2435.5 1532.5 1493.3 1697.9 1347.6 FALSE FALSE TRUE 1259.353017 1610.749338 1512.138469 1570.873137 1100.024625 1930.349846 1575.497825 1948.600296 1511.644618 1394.429 0.903131688 1.155131841 1.0844141 1.126535046 0.788871018 1.384329964 1.129851592 1.39741808 1.08405994 1 10.44545876 -1 0.351998081 0.960729201 6.006771821 0.332999618 0.146027936 35.15354956 0.439565486 0.038964783 119.5114209 0.1 1 5.04604262 HFGAEYR ddPTM_HeLa_Curcumin_4h_R1 1 HFGAEYR 7 0 P04818;P04818-2 P04818 TYMS Thymidylate synthase 0 0 128.86 0.0060973 5607200 234.76 260.16 386.61 256.02 266.92 403.08 205.21 284.13 306.67 254.87 FALSE FALSE TRUE 216.1784983 282.6470711 400.9381067 254.9606571 263.7371533 319.4766644 210.9676403 370.759929 273.0290683 263.7267135 0.819706489 1.071742287 1.520278706 0.966760832 1.000039586 1.211392885 0.799947937 1.405848972 1.035272706 1 8.042899903 -7.015414024 24.51079122 0.916485749 1.136790342 0.151737768 0.204094639 622.5155486 989900.7033 0.03209622 0.040010816 9.65E-08 7.015414024 0.220304593 HFHPLFEYFDYESR ddPTM_HeLa_Curcumin_4h_R1 1 HFHPLFEYFDYESR 14 0 Q96QK1 Q96QK1 VPS35 Vacuolar protein sorting-associated protein 35 0 0 81.239 0.0052353 10818000 2201.5 2320.5 2280.6 2253.7 2233.2 3116.8 2109.1 1881.4 2480 2646.3 FALSE FALSE TRUE 2027.248952 2521.07368 2365.121042 2244.374787 2206.570549 2470.340546 2168.27567 2455.030199 2207.950205 2738.258728 0.740342368 0.920684979 0.863731764 0.819635765 0.805829824 0.902157463 0.791844703 0.896566191 0.806333668 1 11.41904305 -9.559585011 1.327444646 1.000149325 0.830932016 0 0.079672565 0.269160958 0.848701418 0.040796429 0.009578229 2.76E-10 9.559585011 -0.16921731 HFIDVGAGVIDEDYR ddPTM_HeLa_Curcumin_4h_R1 2 HFIDVGAGVIDEDYR 15 0 P33316;A0A0C4DGL3;H0YKC5;H0YKI0;H0YMP1;H0YNW5;H0YMM5;P33316-2;H0YNJ9 P33316;H0YNW5;P33316-2 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 0 0 ; ; 119 0.0011165 44700300 7072.8 6158.7 6234.5 6144.2 7466.1 11053 8756.1 7379.9 6429.2 6272.6 FALSE FALSE TRUE 6512.980417 6691.030585 6465.556054 6118.776928 7377.071634 8760.483207 9001.7726 9629.997537 5723.932845 6490.572383 1.003452397 1.030884518 0.996145744 0.942717617 1.1365826 1.349724291 1.386899655 1.483690031 0.88188414 1 12.66413 -5.299350294 2.001435213 0.999601515 1.43403765 0.937855261 0.049603565 0.036680944 0.281750685 0.004610359 0.014004117 5.02E-06 5.299350294 0.434436135 HFKDEDEDEDVAS(ph)PDGLGR ddPTM_HeLa_Curcumin_4h_R1 3 HFKDEDEDEDVASPDGLGR 19 1 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 0 HFKDEDEDEDVAS(1)PDGLGR;HFKDEDEDEDVAS(1)PDGLGR;HFKDEDEDEDVAS(1)PDGLGR ;; 180.03 1.41E-07 105137600 5010.3 3636.1 4835.4 4705.2 4998.1 5601.7 4538 3086.9 4821.8 4204.3 TRUE FALSE FALSE 4613.729468 3950.388282 5014.604178 4685.731129 4938.500922 4439.844276 4665.324067 4028.0816 4292.860604 4350.399112 1.06053016 0.908051924 1.152676812 1.077080748 1.135183415 1.02056022 1.0723899 0.925910818 0.98677397 1 12.08693205 -4.251454469 23.97958878 1.041348751 0.925910705 0.214791707 0.068334085 951.4363243 2284869.421 0.008989381 0.156056532 5.60E-05 4.251454469 -0.115438046 HFS(ph)QEPR ddPTM_HeLa_Curcumin_4h_R1 1 HFSQEPR 7 0 Q9Y4G2 Q9Y4G2 PLEKHM1 Pleckstrin homology domain-containing family M member 1 1 0 HFS(1)QEPR 72.607 0.008845 0 340.31 260.83 305.69 438.56 290.58 352.64 251.02 287.27 303.78 266.2 TRUE FALSE FALSE 313.3741044 283.374983 317.0191403 436.7453549 287.1150233 279.4984889 258.0629456 374.8573006 270.456094 275.4504302 1.137678762 1.028769433 1.150911763 1.585567881 1.04234734 1.014696142 0.936876176 1.360888419 0.981868476 1 8.105648906 -8.853080977 0.604799926 0.993110449 1.156670864 0.122003967 0.179835605 1.843588625 1.209503608 0.154997519 0.044365564 1.40E-09 8.853080977 0.163560415 HFSGLEEAVYR ddPTM_HeLa_Curcumin_4h_R1 2 HFSGLEEAVYR 11 0 P50990-2;P50990;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 0 0 ; ; 143 0.00092426 8664600 5188.9 3737.3 4607.5 4796.2 4843.4 6124.3 4477.8 4489.8 5000.3 5143.5 FALSE FALSE TRUE 4778.19309 4060.335559 4778.258003 4776.354595 4785.645618 4854.051145 4603.435017 5858.719352 4451.7796 5322.236242 0.897779218 0.762900287 0.897791414 0.897433781 0.89917948 0.912032259 0.864943758 1.100800319 0.836449078 1 12.37781683 -9.004190727 1.027480378 0.994733504 0.899550856 0 0.092248554 0.61557211 1.255748983 0.0370727 0.014141229 9.90E-10 9.004190727 -0.095182648 HFSQS(ph)EETGNEVFGALNEEQPLPR ddPTM_HeLa_Curcumin_4h_R1 2 HFSQSEETGNEVFGALNEEQPLPR 24 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 0 HFS(0.425)QS(0.575)EETGNEVFGALNEEQPLPR;HFS(0.014)QS(0.9)EET(0.086)GNEVFGALNEEQPLPR ; 188.54 2.77E-14 45355000 2903.15 2767.03 2729.2 2993.57 2573.92 1882.35 1713.21 1929.51 2868.37 2599.2 TRUE FALSE FALSE 2673.362614 3006.199744 2830.346553 2981.183401 2543.227685 1491.929392 1761.278062 2517.808717 2553.716987 2689.522007 0.993991723 1.117744988 1.052360437 1.10844358 0.945605828 0.554719161 0.654866574 0.936154718 0.94950589 1 11.39313408 -5.433342048 6.002398766 1.019058025 0.711293772 0.665156862 0.10159257 0.101967027 5.533112441 0.013908484 0.031324197 3.69E-06 5.433342048 -0.307764253 HFVGMLPEKDCR ddPTM_HeLa_Curcumin_4h_R1 1 HFVGMLPEKDCR 12 1 P60981;F6RFD5;P60981-2 P60981 DSTN Destrin 0 0 72.096 0.015888 10893000 3422.1 2483.7 3111.8 2644 2616.8 3761.1 2349 2190.7 3320.4 3277.8 FALSE FALSE TRUE 3151.237174 2698.379961 3227.126045 2633.059829 2585.596369 2981.005464 2414.906618 2858.634345 2956.160427 3391.703306 0.929101661 0.795582549 0.951476516 0.77632375 0.762329761 0.878911035 0.712004088 0.842831488 0.871585796 1 11.72779426 -7.257965446 0.498967522 0.996484957 0.783206188 0.305979658 0.072379901 0.368157976 0.219652549 0.022741514 0.026931446 5.52E-08 7.257965446 -0.213278769 ATPELGSSENSAS(ph)SPPR ddPTM_HeLa_Curcumin_4h_R1 1 ATPELGSSENSASSPPR 17 0 Q9BX63 Q9BX63 BRIP1 Fanconi anemia group J protein 1 0 ATPELGSSENSAS(0.757)S(0.243)PPR 263.07 5.34E-52 62293000 3592.4 2991.1 3352.1 3501.5 3052.3 3454 2144.5 1059.8 3130.8 3051 TRUE FALSE FALSE 3308.057749 3249.637356 3476.331775 3487.011721 3015.903316 2737.601465 2204.668898 1382.928141 2787.359073 3157.022023 1.047841201 1.029336296 1.101142707 1.104525624 0.955300056 0.867146775 0.698338143 0.438048304 0.882907706 1 11.62434861 -4.478458803 1.120915713 1.034730308 0.281098948 0.901558469 0.061787883 0.176945472 0.229551679 0.006826206 0.142411593 3.32E-05 4.478458803 -0.75363136 down HGDPGDAAQQEAK ddPTM_HeLa_Curcumin_4h_R1 2 HGDPGDAAQQEAK 13 0 O14737;O14737-2;Q3HM38;X6R2P6;K7ESJ4 O14737 PDCD5 Programmed cell death protein 5 0 0 ; ; 136.93 0.00023335 5218100 7000.9 6292.5 6342.2 7080.2 6398.5 7296.6 5491.7 5467.3 6951.3 6001.6 FALSE FALSE TRUE 6446.771378 6836.395661 6577.247511 7050.904008 6322.202066 5783.20291 5645.782322 7134.254602 6188.759781 6210.155153 1.0381015 1.100841363 1.059111624 1.135382907 1.01804253 0.931249344 0.909120977 1.148804567 0.996554777 1 12.6004136 -4.201172585 21.8619565 1.023195025 1.148809558 0.254957422 0.065473994 21541.15855 7812711.88 0.009365575 23.62265253 6.29E-05 4.201172585 0.125614533 HGEIDYEAIVK ddPTM_HeLa_Curcumin_4h_R1 1 HGEIDYEAIVK 11 0 A0A087X2I1;P62333 A0A087X2I1 PSMC6 26S protease regulatory subunit 10B 0 0 94.692 0.0045138 1443600 2467.6 2013.5 2062.5 2419.2 2272.7 2686.3 2171.7 1606.1 2511.5 2221.3 FALSE FALSE TRUE 2272.286856 2187.537968 2138.938064 2409.189991 2245.599537 2129.131099 2232.632057 2095.792496 2235.994733 2298.49001 0.98859984 0.951728291 0.930584016 1.048162046 0.976989035 0.926317317 0.971347297 0.91181275 0.97281029 1 11.16647068 -1 0.281377664 0.995831062 0.449792857 0.212547505 0.033846922 44.70945605 0.570055135 0.01399476 12.18514381 0.1 1 -0.546038205 HGESAWNLENR ddPTM_HeLa_Curcumin_4h_R1 4 HGESAWNLENR 11 0 P18669 P18669 PGAM1 Phosphoglycerate mutase 1 0 0 ;;; ;;; 185.99 6.31E-05 57728900 16647.2 15529.2 12076.6 13166.4 15542.4 25779.7 17873.9 14446.2 19504.9 15005.7 FALSE FALSE TRUE 15329.55655 16871.47485 12524.16942 13111.92093 15357.06703 20432.69962 18375.39353 18850.77988 17365.26127 15527.14696 0.98727452 1.086579196 0.806598241 0.844451396 0.989046286 1.315933937 1.183436569 1.214053034 1.118380686 1 13.92250515 -5.27704038 22.24702652 0.974780644 1.232370656 0.617416133 0.094392505 82.33176359 117405.4625 0.012318514 0.02767657 5.28E-06 5.27704038 0.257590012 AATEALGEKSPDSAT(ph)VSGYDIMK ddPTM_HeLa_Curcumin_4h_R1 1 AATEALGEKSPDSATVSGYDIMK 23 1 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;H0Y7E2;K7EL39;J3QRL2;H7C3G6 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 AATEALGEKS(0.039)PDS(0.122)AT(0.534)VS(0.164)GY(0.141)DIMK 61.616 0.0035803 128870000 3393 2514.6 3016.5 2901.1 2942.2 3665.2 3496.1 6485.5 3454.5 3087.9 TRUE FALSE FALSE 3124.44047 2731.950819 3128.294144 2889.096017 2907.116187 2904.996205 3594.191157 8462.899094 3075.549993 3195.204295 0.977853114 0.855016007 0.979059195 0.904197588 0.909837343 0.909173854 1.124870532 2.64862535 0.962551909 1 11.64169246 -4.260145465 3.828437074 0.963713779 2.818885612 0.991100198 0.048296247 0.018216839 0.517984437 0.007670734 0.094811578 5.49E-05 4.260145465 1.855171833 up HGGPGPGGPEPELSPIT(ph)EGSEAR ddPTM_HeLa_Curcumin_4h_R1 1 HGGPGPGGPEPELSPITEGSEAR 23 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 0 HGGPGPGGPEPELS(0.08)PIT(0.916)EGS(0.003)EAR 132.51 2.97E-05 5660300 470.72 552.87 408.42 563.16 547.18 688.91 731.76 685.96 555.84 447.4 TRUE FALSE FALSE 433.4620153 600.6576193 423.5564045 560.8297931 540.6552359 546.0223004 752.2912162 895.1060462 494.8657426 462.9471167 0.936310001 1.297464867 0.914913149 1.211433818 1.167855283 1.179448539 1.625004647 1.933495239 1.068946592 1 8.854703591 -1 0.465700911 0.981340757 26.39094464 0.841855447 0.121045698 18.56896116 0.193681768 0.023331778 456.5282245 0.1 1 25.40960389 HGGS(ph)PQPLAT(ph)TPLSQEPVNPPS(ph)EASPTR ddPTM_HeLa_Curcumin_4h_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 0 HGGS(0.997)PQPLAT(0.435)T(0.435)PLS(0.138)QEPVNPPS(0.749)EAS(0.238)PT(0.008)R 94.633 1.11E-07 11903000 769.93 703.45 533.67 636.23 789.97 759.67 743.28 519.12 582.84 646.09 TRUE FALSE FALSE 708.9892281 764.2530835 553.4482797 633.5974488 780.5501237 602.1058788 764.1344364 677.3972983 518.9039102 668.5415794 1.060501321 1.143164624 0.827844216 0.947730804 1.167541628 0.900625926 1.142987153 1.013246325 0.77617298 1 9.38487348 -4.699761175 25 1.02028313 1.078115804 0.010387758 0.127841561 175.6190307 71179.70502 0.013207088 0.049416387 2.00E-05 4.699761175 0.057832674 HGGS(ph)PQPLAT(ph)TPLSQEPVNPPSEAS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 2 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 0 HGGS(1)PQPLAT(0.711)T(0.289)PLSQEPVNPPS(0.088)EAS(0.761)PT(0.15)R;HGGS(0.999)PQPLAT(0.488)T(0.488)PLS(0.025)QEPVNPPS(0.195)EAS(0.723)PT(0.081)R ; 114.71 9.89E-11 52090000 2146.97 2293.3 2128.3 2172 2605.6 2847.6 2163.08 2018.26 2264.4 1966.43 TRUE FALSE FALSE 1977.035059 2491.522633 2207.17667 2163.01284 2574.529922 2256.975661 2223.770203 2633.618183 2016.000985 2034.763296 0.971629016 1.224477873 1.084733873 1.06302922 1.265272441 1.109207968 1.092888891 1.294311819 0.990779119 1 10.99064526 -7.273386791 24.73132322 0.986602586 1.154496102 0.530666882 0.074978565 351.8324259 728297.0348 0.012047897 0.013833829 5.33E-08 7.273386791 0.167893516 HGGS(ph)PQPLATT(ph)PLSQEPVNPPS(ph)EASPTR ddPTM_HeLa_Curcumin_4h_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 0 HGGS(0.994)PQPLAT(0.425)T(0.562)PLS(0.259)QEPVNPPS(0.581)EAS(0.174)PT(0.004)R 74.052 7.52E-05 14616000 832.01 763.95 890.04 741.92 1091.3 1076.7 1044.1 724.05 775.46 605.72 TRUE FALSE FALSE 766.1555306 829.9824339 923.0256654 738.8501316 1078.28696 853.3802831 1073.394636 944.8095119 690.3939781 626.7687249 1.222389536 1.324224392 1.472673458 1.178824185 1.7203905 1.361555306 1.712584871 1.507429255 1.101513127 1 9.291789382 -6.872809828 0.265702738 0.936555693 1.714785824 0.631292895 0.140853284 0.782288283 0.169426884 0.147166663 0.233125803 1.34E-07 6.872809828 0.778230132 HGGS(ph)PQPLATTPLSQEPVNPPS(ph)EAS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 0 HGGS(0.997)PQPLAT(0.002)T(0.001)PLSQEPVNPPS(0.961)EAS(0.851)PT(0.188)R 80.323 4.31E-06 9429700 684.25 701.96 754.25 695 667.55 717.23 684.15 871.1 673.97 702.71 TRUE FALSE FALSE 630.0908905 762.6342945 782.2031685 692.1242742 659.5899022 568.4684132 703.3454077 1136.69438 600.0371772 727.1291202 0.866546082 1.048829257 1.075741772 0.951858831 0.907115234 0.781798442 0.967290937 1.563263454 0.825214065 1 9.506067764 -4.263352114 5.848506009 0.94202058 1.581070281 0.817635629 0.088898354 0.041348789 6.3546455 0.012372122 0.105016292 5.45E-05 4.263352114 0.639049701 HGGS(ph)PQPLATTPLSQEPVNPPS(ph)EASPTR ddPTM_HeLa_Curcumin_4h_R1 2 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 HGGS(0.999)PQPLATTPLSQEPVNPPS(0.446)EAS(0.432)PT(0.122)R;HGGS(1)PQPLATTPLSQEPVNPPS(0.435)EAS(0.283)PT(0.283)R ; 116.35 2.61E-10 208517000 4393.3 3861.8 5122.5 4273.3 5784.1 4723.6 4140.8 2780.6 4332.3 3901.1 TRUE FALSE FALSE 4045.565669 4195.596784 5312.344356 4255.618217 5715.128385 3743.872114 4256.979704 3628.39214 3857.057529 4036.662935 1.002205469 1.039372584 1.316023766 1.054241656 1.415805203 0.927467112 1.054578936 0.89885933 0.955506464 1 11.97894741 -6.987246807 24.97310066 1.002080799 1.117017378 0.123024783 0.149135109 367.8601071 720335.0246 0.023002406 0.030220272 1.03E-07 6.987246807 0.114936579 HGGS(ph)PQPLATTPLSQEPVNPPSEAS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 HGGS(1)PQPLATTPLSQEPVNPPS(0.034)EAS(0.774)PT(0.191)R 146.8 3.28E-10 23192000 2386.5 2317.9 2259 1933 2658 2809.4 2582.1 1655.7 2157.1 2253.6 TRUE FALSE FALSE 2197.606007 2518.248948 2342.720527 1925.001758 2626.305086 2226.698772 2654.546777 2160.515308 1920.471527 2331.912432 0.94240503 1.079907167 1.004634863 0.82550345 1.126245158 0.954880956 1.138356115 0.926499331 0.823560739 1 11.1872979 HGGS(ph)PQPLATTPLSQEPVNPPSEASPT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 HGGS(0.999)PQPLAT(0.001)TPLSQEPVNPPS(0.073)EAS(0.26)PT(0.667)R 138.9 8.85E-10 179680000 1824 1477.4 1323.9 1069.6 1929.9 1793.3 1486.1 968.44 1065.9 1158.7 TRUE FALSE FALSE 1679.628475 1605.099873 1372.964899 1065.174279 1906.887203 1421.349365 1527.795966 1263.712898 948.9734368 1198.964739 1.400898976 1.33873818 1.145125335 0.888411681 1.590444774 1.18548054 1.274262634 1.054003389 0.791494033 1 10.22757351 -9.570063851 1.371419793 1.001023637 1.256918617 0.284402391 0.195683711 0.536880748 1.821554386 0.125100653 0.029845786 2.69E-10 9.570063851 0.25589498 HGGS(ph)PQPLATTPLSQEPVNPPSEASPTR ddPTM_HeLa_Curcumin_4h_R1 2 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 HGGS(0.996)PQPLAT(0.004)TPLSQEPVNPPSEASPTR;HGGS(0.988)PQPLAT(0.008)T(0.003)PLS(0.001)QEPVNPPSEASPTR ; 124.07 7.31E-11 37418000 5785.1 5236.1 4876.8 5499.6 5152.3 5941.2 4335.5 2939.6 6443.9 4993.3 TRUE FALSE FALSE 5327.203231 5688.685152 5057.538498 5476.844112 5090.862188 4708.928149 4457.142462 3835.870508 5737.020292 5166.816803 1.031041632 1.101003842 0.978849975 1.060003542 0.985299534 0.911378965 0.862647667 0.742404977 1.110358759 1 12.33506002 -4.58751869 1.037756172 1.022631301 0.688376089 0.831306129 0.044231219 0.279803931 0.332512772 0.005354282 0.090496123 2.59E-05 4.58751869 -0.334255212 HGGSPQPLATTPLSQEPVNPPSEAS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 HGGSPQPLATTPLSQEPVNPPSEASPTR 28 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 HGGSPQPLAT(0.003)T(0.006)PLS(0.181)QEPVNPPS(0.228)EAS(0.41)PT(0.172)R 67.447 0.00016867 22082000 1302.8 1173.8 1093.4 1110.2 1876.5 2071.9 1663.7 1050.9 1427 1293.3 TRUE FALSE FALSE 1199.682005 1275.258042 1133.922366 1105.606287 1854.123963 1642.164585 1710.378944 1371.314572 1270.46167 1338.242079 0.896461129 0.952935244 0.847322307 0.826163147 1.385492201 1.227105776 1.278078885 1.024713386 0.94935116 1 10.3861234 -5.766805575 24.99999934 0.933662912 1.232239678 0.716690274 0.097002207 56.10626674 261388.9384 0.014479315 0.02681119 1.71E-06 5.766805575 0.298576766 HGGVCAPAAVAT(ph)SPPGAIPK ddPTM_HeLa_Curcumin_4h_R1 2 HGGVCAPAAVATSPPGAIPK 20 0 A0A494BZT8;Q9Y6A5;E7EMT0 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 0 HGGVCAPAAVAT(0.588)S(0.412)PPGAIPK;HGGVCAPAAVAT(0.896)S(0.104)PPGAIPK ; 95.957 0.00075299 322230000 6689.2 5660.6 5421.8 5731.3 5705.6 7951.5 6054.7 4451.8 6296.9 5124.7 TRUE FALSE FALSE 6159.742762 6149.877041 5622.736678 5707.585399 5637.564446 6302.269268 6224.578587 5809.133326 5606.145824 5302.782944 1.161605675 1.159745195 1.060336947 1.076337738 1.063133171 1.188483356 1.17383243 1.095487669 1.05720824 1 12.37253398 -9.389621747 1.068170274 0.998663168 1.124976606 0.359443435 0.047926178 0.365687343 0.733949918 0.035191305 0.008639521 4.08E-10 9.389621747 0.126313438 HGIVEDWDLMER ddPTM_HeLa_Curcumin_4h_R1 1 HGIVEDWDLMER 12 0 B4DXW1;P61158;F8WDR7 B4DXW1 ACTR3 Actin-related protein 3 0 0 117.2 0.014782 28828000 3922.6 3319.5 3636.2 3274.7 3642 4747.7 3566.7 3386.2 3471.1 3530.5 FALSE FALSE TRUE 3612.122071 3606.422789 3770.960771 3261.150159 3598.571529 3762.973502 3666.772003 4418.636792 3090.329014 3653.184612 0.988759796 0.98719971 1.032239312 0.892686931 0.985050555 1.030052927 1.003719328 1.209530112 0.845927415 1 11.83493895 -4.003997743 1.909961761 0.990117962 1.427991034 0.581558039 0.058421329 0.689608507 1.405628206 0.004933673 0.674508998 9.91E-05 4.003997743 0.437873072 HGLLLPAS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 1 HGLLLPASPVR 11 0 Q96E09 Q96E09 FAM122A Protein FAM122A 1 0 HGLLLPAS(1)PVR 83.243 0.011599 28537000 8614.5 3128.5 6534 5292.2 7370.9 8278.5 8228.3 4908.8 6162.8 6187.7 TRUE FALSE FALSE 7932.653235 3398.9136 6776.155788 5270.302279 7283.006832 6561.445782 8459.163953 6405.470523 5486.756259 6402.722114 1.238950105 0.530854461 1.058324204 0.823134627 1.13748601 1.024790029 1.321182429 1.000429256 0.856941182 1 12.64446968 GGSDGTPRGS(ph)PSPASVSSGR ddPTM_HeLa_Curcumin_4h_R1 1 GGSDGTPRGSPSPASVSSGR 20 1 Q96II5;P10398 Q96II5 ARAF Serine/threonine-protein kinase A-Raf 1 0 GGS(0.002)DGT(0.077)PRGS(0.92)PS(0.002)PASVSSGR 76.068 0.0017275 30185000 1816 1441 1334.9 1910.5 1078.5 1325.9 1070.5 401.48 1925.5 1749.1 TRUE FALSE FALSE 1672.261684 1565.553619 1384.372568 1902.594857 1065.639592 1050.893394 1100.535349 523.8894038 1714.277467 1809.881095 0.923962181 0.865003576 0.764896972 1.051226438 0.588789835 0.58064223 0.608070526 0.289460675 0.947176846 1 10.8216792 -4.47588064 0.434560876 0.976484145 4.15E-13 0.783030035 0.106353177 1.288753647 0.185421887 0.025078869 0.625933511 3.34E-05 4.47588064 -0.976484145 down EGVVGAVEK(ac)TK ddPTM_HeLa_Curcumin_4h_R1 2 EGVVGAVEKTK 11 1 F8W754;O76070 F8W754 SNCG Gamma-synuclein 0 1 ; EGVVGAVEK(1)TK;EGVVGAVEK(1)TK 154.15 2.47E-07 9324600 6082.2 5442.7 5360.4 4411.1 4938.3 7602.8 6271.2 10707.6 5437 5113.3 FALSE TRUE FALSE 5600.787452 5913.142736 5559.061139 4392.848037 4879.413998 6025.893579 6447.152994 13972.29795 4840.574703 5290.986794 1.058552529 1.117587884 1.050666228 0.830251181 0.92221247 1.138897868 1.218516176 2.640773544 0.914871817 1 12.3693211 -4.21680786 2.673448435 1.021033944 3.073300707 0.965362931 0.092364447 0.069076785 0.581984685 0.01264128 0.328746259 6.07E-05 4.21680786 2.052266763 up HGLTSGSAS(ph)PPPPALPLYPDPVR ddPTM_HeLa_Curcumin_4h_R1 2 HGLTSGSASPPPPALPLYPDPVR 23 0 H0YM74;Q92610 H0YM74 ZNF592 Zinc finger protein 592 1 0 HGLT(0.021)S(0.061)GS(0.253)AS(0.665)PPPPALPLYPDPVR;HGLT(0.008)S(0.026)GS(0.081)AS(0.885)PPPPALPLYPDPVR ; 80.68 0.00024981 38545000 1219.68 1181.34 854.16 1024.19 1266.35 2017.41 1190.1 906.87 1408.77 1156.35 TRUE FALSE FALSE 1123.141041 1283.449766 885.815921 1019.952173 1251.249603 1598.976425 1223.491003 1183.370488 1254.231456 1196.533076 0.938662761 1.07264044 0.740318791 0.852422882 1.045729222 1.336341182 1.02253003 0.988999395 1.048221299 1 10.22464456 -5.526778456 24.81306203 0.952063737 1.120684351 0.285379393 0.124301962 97.39445802 619701.2575 0.017538748 0.035200909 2.97E-06 5.526778456 0.168620613 HGNPEEEEWLTAER ddPTM_HeLa_Curcumin_4h_R1 1 HGNPEEEEWLTAER 14 0 Q93008;Q93008-3 Q93008 USP9X Probable ubiquitin carboxyl-terminal hydrolase FAF-X 0 0 165.78 0.00017151 3244100 2044.8 1904.8 2450.3 2239.7 2286.4 2143.4 1552.2 1964.9 2491.4 2070.3 FALSE FALSE TRUE 1882.951922 2069.442424 2541.110274 2230.432715 2259.136173 1698.834679 1595.750554 2563.988965 2218.099653 2142.242771 0.878962902 0.966016762 1.18619155 1.04116711 1.054565899 0.79301688 0.744897159 1.196871335 1.035410031 1 11.06490627 -4.211707198 22.47893146 0.953664287 1.19687552 0.228479404 0.124844049 14923.94679 6744967.348 0.017749527 17.20093951 6.14E-05 4.211707198 0.243211233 HGS(ph)GADS(ph)DYENTQSGDPLLGLEGK ddPTM_HeLa_Curcumin_4h_R1 4 HGSGADSDYENTQSGDPLLGLEGK 24 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 2 0 HGS(0.981)GADS(0.561)DY(0.455)ENT(0.002)QS(0.001)GDPLLGLEGK;HGS(0.952)GADS(0.57)DY(0.36)ENT(0.071)QS(0.046)GDPLLGLEGK;HGS(0.795)GADS(0.596)DY(0.353)ENT(0.119)QS(0.137)GDPLLGLEGK;HGS(0.933)GADS(0.698)DY(0.318)ENT(0.008)QS(0.043)GDPLLGLEGK ;;; 108.23 6.71E-06 61711600 15818.1 13549.5 13391.6 15398.4 16730.5 18149.3 13306.2 6414.48 15137.3 14394.8 TRUE FALSE FALSE 14566.08069 14720.6584 13887.90448 15334.6855 16530.99971 14384.9306 13679.53616 8370.225423 13476.77606 14895.01823 0.977916272 0.988294085 0.932385866 1.02951774 1.109834138 0.965754481 0.918396738 0.561947981 0.904784127 1 13.86254227 -4.218894057 2.346199839 0.995293995 0.428121382 0.854343126 0.052546733 0.151823882 0.896147116 0.006308283 0.182369703 6.04E-05 4.218894057 -0.567172613 S(ph)KGDSDIS(ph)DEEAAQQSK ddPTM_HeLa_Curcumin_4h_R1 1 SKGDSDISDEEAAQQSK 17 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 2 0 S(0.97)KGDS(0.044)DIS(0.88)DEEAAQQS(0.106)K 67.979 0.015903 64860000 5893.1 5305.6 5661.6 5582.2 5244.3 5164.3 3341.2 1371.9 6490.2 3910.4 TRUE FALSE FALSE 5426.654917 5764.192423 5871.423876 5559.102335 5181.765148 4093.165966 3434.94508 1790.185995 5778.241298 4046.286109 1.341144637 1.424563728 1.451064932 1.37387772 1.280622528 1.011585898 0.848913049 0.442426943 1.42803577 1 11.98238262 -4.475104797 1.432974175 1.228846967 0.310549493 0.764118236 0.151961311 0.406203272 0.992344093 0.028182275 0.473345143 3.35E-05 4.475104797 -0.918297473 down HGS(ph)GADSDYENTQSGDPLLGLEGK ddPTM_HeLa_Curcumin_4h_R1 1 HGSGADSDYENTQSGDPLLGLEGK 24 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 0 HGS(0.727)GADS(0.268)DY(0.004)ENT(0.001)QS(0.001)GDPLLGLEGK 63.893 0.0014475 29208000 2184.8 2216.7 2217.4 1938.4 2812.7 3884.6 2259.9 2292.8 2669.9 2270.4 TRUE FALSE FALSE 2011.870775 2408.301671 2299.578795 1930.379414 2779.16039 3078.890172 2323.306712 2991.864165 2377.01865 2349.296231 0.856371686 1.025116219 0.978837306 0.821684123 1.182975715 1.310558511 0.988937317 1.273515075 1.011800308 1 11.19801292 -5.744169998 24.99869576 0.935324105 1.183389799 0.575100059 0.100618856 128.7850824 186424.7795 0.01425719 0.028459967 1.80E-06 5.744169998 0.248065693 VAAAAGS(ph)GPSPPGS(ph)PGHDR ddPTM_HeLa_Curcumin_4h_R1 1 VAAAAGSGPSPPGSPGHDR 19 0 Q9BTU6 Q9BTU6 PI4K2A Phosphatidylinositol 4-kinase type 2-alpha 2 0 VAAAAGS(0.597)GPS(0.403)PPGS(1)PGHDR 147.49 0.00024925 6265100 1189.2 1198.1 1463.4 1585.4 1446.7 1273.4 897.53 311.58 1262.5 1479.3 TRUE FALSE FALSE 1095.073565 1301.658425 1517.634891 1578.840035 1429.449047 1009.282486 922.7122762 406.5793077 1124.006909 1530.705565 0.715404445 0.850364992 0.991461014 1.031445936 0.933849775 0.65935769 0.602801935 0.26561562 0.73430641 1 10.57998109 -4.474099829 1.301314455 0.886147798 0.151099053 0.757751563 0.110248177 0.416888765 0.791166985 0.019669903 0.364508936 3.36E-05 4.474099829 -0.735048746 down HGS(ph)RVLDAIWS(ph)GAALRAR ddPTM_HeLa_Curcumin_4h_R1 1 HGSRVLDAIWSGAALRAR 18 2 A0A3B3ISH6;Q86U38 A0A3B3ISH6 NOP9 Nucleolar protein 9 2 0 HGS(1)RVLDAIWS(1)GAALRAR 63.062 0.01713 3426000 705.02 543.32 800.2 809.61 676.39 843.95 912.95 754.71 838.64 642.3 TRUE FALSE FALSE 649.2169231 590.2821598 829.8561159 806.2600483 668.324491 668.9052567 938.5649199 984.8176047 746.6432902 664.6198772 0.976824415 0.888150024 1.24861766 1.213114558 1.005574034 1.006447865 1.412183042 1.481775732 1.123414023 1 9.376385631 -1 0.454101725 0.992857928 13.47005618 0.552199021 0.125848665 35.86416101 0.383689446 0.02572556 419.4480009 0.1 1 12.47719825 HGS(ph)YEDAVHSGALND ddPTM_HeLa_Curcumin_4h_R1 3 HGSYEDAVHSGALND 15 0 P17987;E7EQR6;F5H282 P17987 TCP1 T-complex protein 1 subunit alpha 1 0 HGS(0.998)Y(0.002)EDAVHSGALND;HGS(1)YEDAVHSGALND;HGS(0.998)YEDAVHS(0.002)GALND ;; 113.43 0.0018676 48113000 8452.6 8899.1 7108.1 8091.9 9530.6 9790.9 7642.8 7714.6 8393.3 7921.2 TRUE FALSE FALSE 7783.567791 9668.29855 7371.532439 8058.417862 9416.95382 7760.156974 7857.236398 10066.74603 7472.575989 8196.46111 0.949625416 1.179569868 0.899355507 0.983158189 1.148904837 0.946769206 0.958613271 1.228182003 0.911683212 1 13.00078543 -4.256169443 24.54664381 0.993335461 1.228182131 0.374199694 0.089340371 326.4217797 1520364.221 0.011149539 0.126321206 5.54E-05 4.256169443 0.23484667 HGSGADS(ph)DY(ph)ENTQSGDPLLGLEGKR ddPTM_HeLa_Curcumin_4h_R1 1 HGSGADSDYENTQSGDPLLGLEGKR 25 1 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 2 0 HGS(0.299)GADS(0.711)DY(0.988)ENT(0.001)QSGDPLLGLEGKR 109.28 1.03E-07 15674000 3465.6 2437.7 2240.1 3349.9 2393.3 3359.2 2529.7 1056.5 3948.7 2984.1 TRUE FALSE FALSE 3191.294103 2648.403926 2323.120077 3336.039001 2364.761461 2662.464054 2600.676574 1378.621986 3515.537489 3087.797253 1.03351802 0.857700072 0.752355121 1.080394446 0.765840911 0.862253521 0.842243308 0.446474258 1.138526011 1 11.59236231 -3.642088547 0.432836653 1.004890542 3.01E-27 0.58014547 0.123695635 4.10473973 0.35253448 0.02672545 2.379607607 0.000227988 3.642088547 -1.004890542 HGTDLWIDNMSSAVPNHS(ph)PEKK ddPTM_HeLa_Curcumin_4h_R1 3 HGTDLWIDNMSSAVPNHSPEKK 22 1 Q8N6H7;H0YF45;E9PJT7;E9PK28;E9PN48;E9PIY6 Q8N6H7 ARFGAP2 ADP-ribosylation factor GTPase-activating protein 2 1 0 HGTDLWIDNMS(0.023)S(0.023)AVPNHS(0.955)PEKK;HGTDLWIDNMS(0.118)S(0.118)AVPNHS(0.763)PEKK;HGTDLWIDNMS(0.067)S(0.067)AVPNHS(0.866)PEKK ;; 82.586 0.00024154 176252000 8856.6 7616.8 5399 5613.5 12524.3 19490.2 9876.5 9333.9 12761.3 7249.3 TRUE FALSE FALSE 8155.590765 8275.162252 5599.091689 5590.272824 12374.9559 15447.71282 10153.60801 12179.76314 11361.41732 7501.212635 1.087236312 1.1031766 0.746424873 0.745249215 1.649727385 2.059362075 1.353595545 1.623705891 1.514610753 1 12.87290812 -5.745168895 24.23687932 1.00425851 1.67658118 0.594343769 0.257889432 68.29618864 101734.6022 0.029534388 0.058910306 1.80E-06 5.745168895 0.67232267 HGVESTLER ddPTM_HeLa_Curcumin_4h_R1 1 HGVESTLER 9 0 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 0 106.18 0.008289 821400 544.66 529.22 386.16 653.3 650.19 651.09 485.63 437.01 693.48 488.12 FALSE FALSE TRUE 501.5495863 574.9634186 400.4714293 650.5968177 642.4369089 516.0465947 499.2554708 570.2523373 617.406979 505.0821337 0.993005994 1.13835628 0.792883776 1.288101032 1.271945424 1.021708273 0.98846393 1.129028923 1.222389267 1 8.9803742 -6.249027108 24.9952818 0.995595094 1.132214449 0.11464497 0.137711916 857.3671443 1726527.655 0.017481075 0.028856311 5.64E-07 6.249027108 0.136619355 HGYIGEFEIIDDHR ddPTM_HeLa_Curcumin_4h_R1 4 HGYIGEFEIIDDHR 14 0 I3L3P7;I3L246;H3BN98;P62244 I3L3P7 RPS15A 40S ribosomal protein S15a 0 0 ;;; ;;; 124.3 0.00041694 283188200 15673.7 15051.6 14316.7 14912.7 14617.8 15087.4 11919.7 9516.4 15101.6 14179.2 FALSE FALSE TRUE 14433.11011 16352.59324 14847.2895 14850.9952 14443.49228 11958.10317 12254.1347 12417.90655 13444.99226 14671.92614 0.983722925 1.11454986 1.011952306 1.012204877 0.984430547 0.815032945 0.835209677 0.846371937 0.916375405 1 13.84077066 -5.30867624 5.118785378 1.004729712 0.832157827 0.744400699 0.046012214 0.062917082 3.90058574 0.005600803 0.013042701 4.91E-06 5.30867624 -0.172571885 HHEDNLLR ddPTM_HeLa_Curcumin_4h_R1 2 HHEDNLLR 8 0 O75643 O75643 SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 0 0 ; ; 157.33 1.04E-08 9680700 1368.33 1161.62 983.27 1353.18 1383.1 1852.15 1097.65 1156.08 1453.74 1270.98 FALSE FALSE TRUE 1260.025237 1262.025257 1019.710851 1347.5809 1366.607436 1467.993212 1128.447105 1508.56347 1294.268359 1315.14646 0.958087388 0.959608146 0.775359157 1.024662226 1.039129464 1.116220327 0.858039115 1.147068798 0.984124885 1 10.36100776 -6.036449654 24.99240502 0.961089233 1.032464171 0.204921285 0.093364552 920.6012647 631227.0037 0.013507459 0.022404424 9.19E-07 6.036449654 0.071374938 HHGDVMDLQFFDQER ddPTM_HeLa_Curcumin_4h_R1 1 HHGDVMDLQFFDQER 15 0 B4E301;F5H0E3;B4DVD1;Q8NFH3-2;Q8NFH3 B4E301 NUP43 Nucleoporin Nup43 0 0 85.837 0.0038604 4682200 1035.9 1115 1160.6 1100.6 983.24 1383.2 885.75 923.76 1214.5 1071 FALSE FALSE TRUE 953.9074219 1211.375632 1203.612857 1096.046009 971.5155052 1096.308728 910.6017611 1205.410172 1081.272389 1108.21717 0.860758566 1.09308506 1.086080318 0.98901735 0.876647223 0.989254415 0.821681693 1.087702125 0.97568637 1 10.11402491 -4.184065324 21.08480382 0.951583961 1.087719924 0.134120779 0.0863693 42832.11933 11666678.15 0.012856313 125.7527527 6.55E-05 4.184065324 0.136135963 HHYEQQQEDLAR ddPTM_HeLa_Curcumin_4h_R1 1 HHYEQQQEDLAR 12 0 F5GWX5;A0A2R8YER1;Q14839-2;Q14839;A0A2R8YFD8;A0A0C4DGG9;A0A2U3TZM0;A0A2R8Y521;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8Y212;A0A2R8Y8C1;A0A2R8YDJ9;A0A2R8YD40;A0A2R8Y5Z7;A0A2R8YE38;A0A2R8Y4X2;A0A2R8YDW2;A0A2R8Y5M9;A0A2R8Y7I0;K7EMY3;Q8TDI0;Q12873-2;Q12873;Q12873-3;A0A5F9ZHX5 F5GWX5;Q12873-2 CHD4;CHD5;CHD3 Chromodomain-helicase-DNA-binding protein 4;Chromodomain-helicase-DNA-binding protein 5;Chromodomain-helicase-DNA-binding protein 3 0 0 81.676 0.018419 1608200 1474.5 1177.1 1370.1 1552.5 1336.7 1624.3 1470.8 908.39 1625.8 1491.4 FALSE FALSE TRUE 1357.791769 1278.843279 1420.877111 1546.076166 1320.760726 1287.40187 1512.06669 1185.353929 1447.453808 1543.226039 0.879839852 0.828681766 0.920718725 1.001846863 0.855843987 0.834227675 0.979808953 0.768101302 0.937940244 1 10.59173368 -9.188359157 0.81006385 1.004330813 0.887352946 0.171832005 0.069169909 0.691466352 0.773876237 0.051112303 0.012635835 6.48E-10 9.188359157 -0.116977867 HIADLAGNSEVILPVPAFNVINGGSHAGNK ddPTM_HeLa_Curcumin_4h_R1 1 HIADLAGNSEVILPVPAFNVINGGSHAGNK 30 0 P06733;A0A2R8Y6G6;K7EM90;P06733-2;A0A2R8YEM5 P06733 ENO1 Alpha-enolase;Enolase 0 0 76.691 0.00041238 568520 671.4 732.4 430.16 458.15 744.18 884.31 729.76 655.04 453.44 235.62 FALSE FALSE TRUE 618.2579815 795.7053925 446.102108 456.2542967 735.3061395 700.8941378 750.2351016 854.7586806 403.6987665 243.8077775 2.535841916 3.263658776 1.829728783 1.871368918 3.01592569 2.874781703 3.0771582 3.505871262 1.655807582 1 7.929600338 -9.425513417 0.248168765 5.41E-26 3.138474094 0.567298837 0.514995444 3.008141196 0.243292116 2.922498053 0.486003632 3.75E-10 9.425513417 3.138474094 HIAEEADR ddPTM_HeLa_Curcumin_4h_R1 4 HIAEEADR 8 0 P67936;A0A2R8Y5V9;A0A2R8YGX3;A0A2R8YH90;A0A2R8YE05;P67936-2;K7ENT6;A0A2R8YEU4;A0A2R8YHD2;A0A5F9UN72;A0A087WWU8;P06753-2;P06753-5;P06753-3;P06753-6;P06753-4;P06753-7;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 P67936;A0A087WWU8;J3KN67 TPM4;TPM3 Tropomyosin alpha-4 chain;Tropomyosin alpha-3 chain 0 0 ;;; ;;; 176.09 0.00043856 82118700 5399.4 9635.2 4080.38 4361.62 3724.43 5932.1 4255.56 3946.68 3860.77 5095.73 FALSE FALSE TRUE 4972.031793 10468.02375 4231.602472 4343.572772 3680.018605 4701.715591 4374.95956 5150.004564 3437.25319 5272.806238 0.942957425 1.985285118 0.802533278 0.823768706 0.697924111 0.891691327 0.829721284 0.976710376 0.651883084 1 12.36435527 HIAEEADRK(ac)YEEVAR ddPTM_HeLa_Curcumin_4h_R1 1 HIAEEADRKYEEVAR 15 2 P67936;A0A2R8Y5V9;A0A2R8YGX3;A0A2R8YH90;A0A2R8YE05;P67936-2;K7ENT6;A0A2R8YEU4;A0A2R8YHD2;A0A5F9UN72;A0A087WWU8;P06753-2;P06753-5;P06753-3;P06753-6;P06753-4;P06753-7;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 P67936;A0A087WWU8;J3KN67 TPM4;TPM3 Tropomyosin alpha-4 chain;Tropomyosin alpha-3 chain 0 1 HIAEEADRK(1)YEEVAR 76.073 0.0064606 3841000 426.65 636.86 360.56 607.33 788.19 1039.7 835.92 885.89 1342.5 921.65 FALSE TRUE FALSE 392.8802023 691.9073406 373.9226708 604.8170294 778.791349 824.0545002 859.3736654 1155.993783 1195.231109 953.6772689 0.411963476 0.725515185 0.392085125 0.634194658 0.816619389 0.864081096 0.901115811 1.212143584 1.253286775 1 9.89735732 -4.237007816 0.970366853 0.688964702 1.482788641 0.221396888 0.245723553 1.980112918 1.368451454 0.037175443 1.660108372 5.79E-05 4.237007816 0.793823938 HIAFT(ph)PESQR ddPTM_HeLa_Curcumin_4h_R1 1 HIAFTPESQR 10 0 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5;Q5H9R7-3 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 1 0 HIAFT(1)PESQR 91.858 0.017083 5464300 1792.8 1792.3 1722.6 1683.6 1983.4 2085.1 1535.3 1419.2 1638.2 1301.9 TRUE FALSE FALSE 1650.897988 1947.218426 1786.441071 1676.633709 1959.74925 1652.626756 1578.376386 1851.907547 1458.493559 1347.140928 1.225482764 1.445445228 1.326098134 1.24458672 1.45474702 1.226766051 1.171649048 1.374694739 1.082658487 1 10.39568507 -8.446971808 0.793037388 1.018806569 1.312172045 0.572319138 0.09225436 0.275683965 0.361824816 0.039392408 0.020576353 3.57E-09 8.446971808 0.293365477 HIDFSLR ddPTM_HeLa_Curcumin_4h_R1 2 HIDFSLR 7 0 P46781 P46781 RPS9 40S ribosomal protein S9 0 0 ; ; 162.31 0.0046442 30957000 2299.7 1562.56 1818.26 1685.47 1967.42 2355.9 1727.72 1737.66 1663.54 1833.02 FALSE FALSE TRUE 2117.676318 1697.620724 1885.646315 1678.495972 1943.959801 1867.259784 1776.195173 2267.464535 1481.053824 1896.717309 1.116495489 0.895030965 0.994163077 0.884947886 1.024907503 0.984469206 0.936457513 1.195467835 0.780851114 1 10.88928896 -7.275317271 24.86017646 1.055011756 0.983510655 0 0.121853116 1126.057025 2017159.99 0.014721257 0.016881137 5.30E-08 7.275317271 -0.0715011 HIDLVEGDEGR ddPTM_HeLa_Curcumin_4h_R1 2 HIDLVEGDEGR 11 0 P19367-4;P19367-2;P19367;P19367-3 P19367-4 HK1 Hexokinase-1 0 0 ; ; 108.98 0.0056582 19461900 10593.2 8488.5 9201.1 10262.3 8260.3 7131.4 4362.8 3441.8 10720.7 9355.8 FALSE FALSE TRUE 9754.737042 9222.208116 9542.10086 10219.83732 8161.801317 5652.267253 4485.208426 4491.188976 9544.666032 9680.913354 1.007625695 0.952617566 0.985661219 1.055668711 0.843081744 0.583856817 0.463304263 0.46392203 0.985926191 1 13.24092745 -5.288390801 2.037371155 1.001533162 0.463699083 0.982092939 0.030042455 0.02663939 0.212151809 0.004186979 0.012724979 5.15E-06 5.288390801 -0.537834079 down HIEDTGSTPS(ph)IGENDLK ddPTM_HeLa_Curcumin_4h_R1 2 HIEDTGSTPSIGENDLK 17 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 0 HIEDTGST(0.008)PS(0.992)IGENDLK;HIEDTGST(0.009)PS(0.991)IGENDLK ; 176.08 1.34E-05 68284600 3677.9 3141.7 3077.3 3405.5 3839.2 4730.1 3123.2 1427.43 4261.1 3544.9 TRUE FALSE FALSE 3386.790334 3413.254549 3191.347445 3391.408943 3793.420047 3749.023941 3210.828586 1862.646836 3793.667991 3668.085011 0.923312934 0.930527656 0.870030939 0.924572068 1.034169065 1.022065718 0.875341923 0.507798165 1.03423666 1 11.84081136 -4.281868166 3.223248437 0.95926259 0.453510177 0.868229922 0.053453589 0.080480697 1.337412445 0.007547271 0.09882481 5.23E-05 4.281868166 -0.505752414 HIEPELAGRDS(ph)PIR ddPTM_HeLa_Curcumin_4h_R1 2 HIEPELAGRDSPIR 14 1 P86791;P86790 P86791 CCZ1;CCZ1B Vacuolar fusion protein CCZ1 homolog;Vacuolar fusion protein CCZ1 homolog B 1 0 HIEPELAGRDS(1)PIR;HIEPELAGRDS(1)PIR ; 137.81 0.00036557 49693000 2985.05 3222.2 3331.5 3101.9 3151.3 2991.5 2218.21 1587.97 2627.49 2759.7 TRUE FALSE FALSE 2748.780143 3500.71261 3454.968321 3089.06516 3113.722806 2371.029179 2280.447003 2072.134743 2339.260921 2855.59937 0.962593063 1.225911676 1.209892521 1.081757193 1.090392034 0.830308763 0.798587865 0.725639165 0.819183862 1 11.47957787 -5.126938711 4.061970661 1.031888799 0.771808163 0.539628736 0.113968016 0.14535064 4.059292469 0.015948258 0.043704287 7.47E-06 5.126938711 -0.260080636 HIFSEDTSDFSGMSETK ddPTM_HeLa_Curcumin_4h_R1 1 HIFSEDTSDFSGMSETK 17 0 P36952 P36952 SERPINB5 Serpin B5 0 0 103.77 0.00072796 0 1523.1 1081.4 1205.3 1229.1 1239.8 2278.4 1401 1187.7 1532 1405.2 FALSE FALSE TRUE 1402.545028 1174.871397 1249.969478 1224.01431 1225.016195 1805.834157 1440.308289 1549.824263 1363.943433 1454.030595 0.964591139 0.808010094 0.859658306 0.841807809 0.842496849 1.241950591 0.990562574 1.065881466 0.938043145 1 10.50584191 -5.275035112 24.97443816 0.940923769 1.088574662 0.472477579 0.090269567 694.076417 1274970.291 0.014568343 0.032738623 5.31E-06 5.275035112 0.147650893 HIILVLSGK ddPTM_HeLa_Curcumin_4h_R1 1 HIILVLSGK 9 0 H3BRK5;H3BMW1;H3BNF0;H3BNS4;Q9Y5Y2 H3BRK5 NUBP2 Cytosolic Fe-S cluster assembly factor NUBP2 0 0 88.948 0.0077765 0 1680.5 810 1113 952.53 1135.9 3835.9 2415 2026.1 1293.1 1451.6 FALSE FALSE TRUE 1547.486652 880.0127907 1154.248759 948.5886832 1122.355134 3040.2911 2482.7584 2643.848563 1151.250165 1502.042992 1.030254567 0.585877232 0.768452544 0.631532312 0.747219048 2.024103915 1.652920997 1.760168369 0.766456201 1 10.55271039 -5.263696551 24.99838627 0.917878603 1.796450105 0.852555982 0.189661908 66.16410029 732778.4192 0.030646869 0.071763976 5.45E-06 5.263696551 0.878571502 HIISATSLST(ph)SPTELGSR ddPTM_HeLa_Curcumin_4h_R1 1 HIISATSLSTSPTELGSR 18 0 Q5JSZ5;Q5JSZ5-5;A0A1W2PQP5 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 HIISATSLS(0.002)T(0.989)S(0.009)PTELGSR 295.22 2.88E-81 34228000 1887.5 1845.3 1402 1248.4 1583.1 2883.3 1620.7 1116.2 2551.1 1205.6 TRUE FALSE FALSE 1738.102383 2004.79951 1453.959353 1243.234452 1564.222566 2285.271079 1666.17248 1456.524242 2271.250713 1247.49451 1.393274575 1.607060787 1.165503609 0.996585108 1.253891343 1.831888685 1.33561508 1.16755964 1.820649866 1 10.28481775 -9.226744262 0.918787913 0.995656159 1.348762962 0 0.339072884 0.700595013 1.044081056 0.166510813 0.04420649 5.93E-10 9.226744262 0.353106804 HIISATSLSTS(ph)PTELGSR ddPTM_HeLa_Curcumin_4h_R1 3 HIISATSLSTSPTELGSR 18 0 Q5JSZ5;Q5JSZ5-5;A0A1W2PQP5 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 HIISATSLS(0.001)T(0.169)S(0.804)PT(0.025)ELGSR;HIISATS(0.001)LS(0.002)T(0.053)S(0.944)PTELGSR;HIISATSLST(0.073)S(0.916)PT(0.011)ELGSR ;; 285.79 2.84E-68 69703000 7957.6 6036.4 5810.8 5233.4 7356.1 10863.5 5921.5 4808.8 8497.1 5917.4 TRUE FALSE FALSE 7327.747563 6558.159518 6026.15336 5211.745577 7268.383312 8610.287643 6087.641353 6274.980983 7564.989389 6123.02921 1.196752018 1.071064549 0.984178444 0.851171111 1.187056776 1.406213714 0.994220531 1.024816438 1.235497844 1 12.58002985 -9.719601046 1.634740621 1.000084154 1.106627793 0 0.160728274 0.962934408 4.652580687 0.108579187 0.023842874 1.91E-10 9.719601046 0.106543639 HIKEEPLS(ph)EEEPCTSTAIAS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 1 HIKEEPLSEEEPCTSTAIASPEK 23 1 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 2 0 HIKEEPLS(0.952)EEEPCT(0.04)S(0.039)T(0.065)AIAS(0.905)PEK 55.314 0.0048431 289770000 7750 6429.8 7586.6 7788 7955 8155.6 6317.3 4768.9 7147.3 6872.2 TRUE FALSE FALSE 7136.579322 6985.563261 7867.76607 7755.77532 7860.141821 6464.036627 6494.546436 6222.915657 6363.259072 7111.008438 1.003595957 0.982359017 1.106420578 1.090671652 1.105348403 0.909018275 0.913308779 0.875110149 0.894846227 1 12.79583845 -5.137639106 7.764358767 1.021068244 0.898571122 0.469371506 0.061807475 0.167816195 9.900886087 0.007577361 0.019448043 7.28E-06 5.137639106 -0.122497122 HIKEEPLS(ph)EEEPCTSTAIASPEKK ddPTM_HeLa_Curcumin_4h_R1 2 HIKEEPLSEEEPCTSTAIASPEKK 24 2 Q9Y2X3 Q9Y2X3 NOP58 Nucleolar protein 58 1 0 HIKEEPLS(0.903)EEEPCT(0.093)S(0.003)T(0.001)AIASPEKK;HIKEEPLS(0.963)EEEPCT(0.036)STAIASPEKK ; 83.359 5.53E-05 153049000 4653.1 3955.5 4110.2 4212 4313.8 4963.4 3691.5 3329.1 4992.1 4579 TRUE FALSE FALSE 4284.802225 4297.395795 4262.527628 4194.57186 4262.360752 3933.934891 3795.073555 4344.127265 4444.47912 4738.119909 0.904325409 0.906983335 0.899624262 0.885281914 0.899589043 0.830273392 0.800966127 0.916846207 0.938025885 1 12.21009899 -11.07785319 0.140978365 1.223317253 0.813166507 0.494677623 0.036697866 12.88377182 0.252796397 1.002706327 0.11092916 8.36E-12 11.07785319 -0.410150746 HIPGYQQAS(ph)S(ph)S(ph)Y(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 HIPGYQQASSSYK 13 0 H7C002;A5D8W1-4;A5D8W1-3;A5D8W1-2;A5D8W1 H7C002 CFAP69 Cilia- and flagella-associated protein 69 4 0 HIPGY(0.044)QQAS(0.986)S(0.986)S(0.986)Y(0.998)K 44.309 0.019296 5827600 0 67.222 0 0 144.3 189.97 0 0 113.65 0 TRUE FALSE FALSE 0 73.03237014 0 0 142.5793167 150.5680806 0 0 101.1828793 0 0 HIVSNDS(ph)SDSDDESHEPKGTENEDAGSDYQSDNQASWIHR ddPTM_HeLa_Curcumin_4h_R1 1 HIVSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHR 40 1 P47712 P47712 PLA2G4A Cytosolic phospholipase A2;Phospholipase A2;Lysophospholipase 1 0 HIVS(0.034)NDS(0.254)S(0.225)DS(0.199)DDES(0.127)HEPKGT(0.014)ENEDAGS(0.005)DY(0.136)QS(0.006)DNQAS(0.001)WIHR 43.359 0.0037457 15102000 1714.6 1685 1426.6 1342.7 1738.6 1976.4 1483 1265.4 2192.2 2193.4 TRUE FALSE FALSE 1578.887601 1830.643892 1479.471051 1337.144263 1717.868331 1566.472361 1524.608989 1651.214635 1951.721145 2269.620487 0.695661504 0.806585904 0.651858344 0.589148834 0.756896733 0.690191321 0.671746223 0.727528961 0.85993282 1 11.14823536 -9.297990469 0.530995365 1.064472297 0.686431462 0.617328024 0.06950528 0.460615357 0.176122617 0.089820489 0.013717067 5.04E-10 9.297990469 -0.378040835 HIVSNDSS(ph)DSDDES(ph)HEPK ddPTM_HeLa_Curcumin_4h_R1 1 HIVSNDSSDSDDESHEPK 18 0 P47712 P47712 PLA2G4A Cytosolic phospholipase A2;Phospholipase A2;Lysophospholipase 2 0 HIVS(0.002)NDS(0.342)S(0.656)DS(0.022)DDES(0.978)HEPK 102.29 0.0026121 17117000 3557.7 2769.9 2933.2 2832.5 3600.8 3381.6 2851.8 2368 3089.3 2722.3 TRUE FALSE FALSE 3276.104291 3009.317814 3041.906972 2820.779866 3557.862812 2680.218042 2931.813833 3089.992299 2750.411519 2816.899722 1.163017719 1.068308463 1.079877622 1.001377452 1.263042054 0.951477974 1.040794534 1.096947923 0.976396674 1 11.45989249 HIVSNDSS(ph)DSDDESHEPK ddPTM_HeLa_Curcumin_4h_R1 1 HIVSNDSSDSDDESHEPK 18 0 P47712 P47712 PLA2G4A Cytosolic phospholipase A2;Phospholipase A2;Lysophospholipase 1 0 HIVS(0.099)NDS(0.192)S(0.657)DS(0.051)DDESHEPK 140.88 0.00013684 76569000 6198.8 4876.6 5111.7 4664.1 5564.8 5067.8 3729.4 3368.9 4591.6 4603.6 TRUE FALSE FALSE 5708.158439 5298.111574 5301.144099 4644.80119 5498.443394 4016.681154 3834.036927 4396.062101 4087.912968 4763.574757 1.198293032 1.112213378 1.112849985 0.975066295 1.154268312 0.84320733 0.804865489 0.922849399 0.858160767 1 12.21782891 -5.253524598 24.41063499 1.09293458 0.851763184 0.434060843 0.100301991 216.923949 669029.8492 0.012112309 0.030254071 5.58E-06 5.253524598 -0.241171396 HIVSNDSSDS(ph)DDESHEPK ddPTM_HeLa_Curcumin_4h_R1 1 HIVSNDSSDSDDESHEPK 18 0 P47712 P47712 PLA2G4A Cytosolic phospholipase A2;Phospholipase A2;Lysophospholipase 1 0 HIVS(0.001)NDS(0.019)S(0.163)DS(0.798)DDES(0.019)HEPK 140.4 0.00014145 59870000 7853 6478.4 6434.6 6856 9332.4 7731.1 5245.8 4783.1 6946.6 6048.9 TRUE FALSE FALSE 7231.426764 7038.364029 6673.071936 6827.631689 9221.117225 6127.582713 5392.98303 6241.445171 6184.57536 6259.098825 1.155346315 1.124501182 1.066139411 1.090833022 1.473234004 0.978988012 0.861622924 0.997179522 0.988093579 1 12.61173924 -5.015743522 24.98893277 1.10729726 0.927127214 0.282842144 0.131681352 702.2060071 1114582.311 0.018721567 0.04942098 9.64E-06 5.015743522 -0.180170046 HIVSNDSSDS(ph)DDESHEPKGTENEDAGSDYQSDNQASWIHR ddPTM_HeLa_Curcumin_4h_R1 1 HIVSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHR 40 1 P47712 P47712 PLA2G4A Cytosolic phospholipase A2;Phospholipase A2;Lysophospholipase 1 0 HIVS(0.004)NDS(0.093)S(0.078)DS(0.227)DDES(0.227)HEPKGT(0.067)ENEDAGS(0.227)DY(0.074)QS(0.002)DNQASWIHR 56.313 7.54E-05 15924000 1778.6 1999.7 1672.3 1767.9 1993.7 2693.9 1644.5 1278.7 2756.4 2533.2 TRUE FALSE FALSE 1637.821933 2172.545158 1734.276909 1760.584898 1969.92643 2135.154773 1690.640244 1668.569744 2454.029816 2621.228511 0.624829894 0.828827074 0.661627516 0.671664027 0.751527927 0.814562624 0.644980106 0.636560199 0.936213613 1 11.35602741 -9.391648774 0.965014921 1.011353465 0.702389242 0.685457887 0.071067651 0.259020415 0.405360674 0.058624726 0.012952652 4.06E-10 9.391648774 -0.308964223 HIYYITGETK ddPTM_HeLa_Curcumin_4h_R1 4 HIYYITGETK 10 0 P07900;P07900-2;Q58FG0 P07900 HSP90AA1;HSP90AA5P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A5 0 0 ;;; ;;; 142.98 5.18E-06 142088000 28820.6 24689.6 25263.7 27578.3 25708.9 31191.2 24098.9 24750 28431.6 24393 FALSE FALSE TRUE 26539.4191 26823.65901 26199.99495 27464.1883 25402.33816 24721.79352 24775.05028 32296.16107 25312.72461 25240.65493 1.051455248 1.062716442 1.038007731 1.088093331 1.006405667 0.979443425 0.981553384 1.27952944 1.002855301 1 14.62346172 -4.255254412 24.98371358 1.026158683 1.279529553 0.833960258 0.034266813 220.8220662 891969.2624 0.005124018 0.063517222 5.56E-05 4.255254412 0.25337087 HK(ac)LDVTSVEDYK ddPTM_HeLa_Curcumin_4h_R1 1 HKLDVTSVEDYK 12 1 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 1 HK(1)LDVTSVEDYK 129.37 0.00059593 5452200 4066.5 5875.8 4626.6 4062.6 7952.4 12129 8897.5 6644.3 9674.6 4361.9 FALSE TRUE FALSE 3744.632234 6383.67797 4798.065866 4045.790038 7857.572824 9613.308678 9147.139904 8670.116483 8613.320585 4513.4757 0.829656009 1.414359663 1.063053439 0.896380153 1.740913953 2.129912581 2.026628814 1.920940104 1.908356477 1 12.14002312 -5.654744972 3.734660894 0.968545824 2.016332077 0.508177381 0.339070004 0.05408606 1.436053902 0.026298555 0.05459917 2.21E-06 5.654744972 1.047786252 HKAEEVEDETVELDVS(ph)DEEMAR ddPTM_HeLa_Curcumin_4h_R1 6 HKAEEVEDETVELDVSDEEMAR 22 1 H3BSB3;H3BNT4;Q99547 H3BSB3 MPHOSPH6 M-phase phosphoprotein 6 1 0 HKAEEVEDETVELDVS(1)DEEMAR;HKAEEVEDETVELDVS(1)DEEMAR;HKAEEVEDETVELDVS(1)DEEMAR;HKAEEVEDETVELDVS(1)DEEMAR;HKAEEVEDETVELDVS(1)DEEMAR;HKAEEVEDETVELDVS(1)DEEMAR ;;;;; 155.39 5.41E-07 51543300 27441.6 26168.3 22357.2 26357.9 26397.8 34349.3 28704.9 21343.26 31414 27959.2 TRUE FALSE FALSE 25269.5684 28430.17125 23185.7775 26248.83799 26083.02348 27224.86798 29510.28224 27850.72172 27967.96279 28930.78012 0.873449257 0.982696323 0.801422478 0.907297967 0.901566545 0.9410347 1.020030643 0.962667498 0.966719967 1 14.82031761 -4.905877777 6.227574614 0.926591266 0.990609998 0.198450059 0.055946958 0.309269129 16.9549276 0.009010563 0.027655638 1.24E-05 4.905877777 0.064018731 HKELAPYDENWFYTR ddPTM_HeLa_Curcumin_4h_R1 2 HKELAPYDENWFYTR 15 1 P39019;M0R2L9;M0QYF7;M0R140 P39019 RPS19 40S ribosomal protein S19 0 0 ; ; 100.43 0.001762 283720000 13825.6 9379.2 12048.4 10296.7 9819.3 27250.4 19430.4 17159.8 14618.3 12939.5 FALSE FALSE TRUE 12731.28917 10189.89626 12494.9243 10254.09498 9702.211261 21598.35986 19975.56473 22391.74403 13014.70906 13389.14666 0.950866362 0.761056437 0.933212894 0.765851271 0.724632533 1.613124451 1.491922169 1.672380219 0.972034245 1 13.7087764 -5.252192235 24.91295055 0.925576433 1.582420333 0.900108749 0.10889353 163.5821754 440709.3416 0.017110888 0.04296569 5.60E-06 5.252192235 0.6568439 HKSGS(ph)MEEDVDTSPGGDYYTSPS(ph)SPTSSSR ddPTM_HeLa_Curcumin_4h_R1 1 HKSGSMEEDVDTSPGGDYYTSPSSPTSSSR 30 1 A0A286YEX4;P08651-4;P08651-5;P08651-3;P08651-6;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 2 0 HKS(0.408)GS(0.515)MEEDVDT(0.049)S(0.026)PGGDY(0.007)Y(0.003)T(0.017)S(0.031)PS(0.604)S(0.241)PT(0.058)S(0.026)S(0.012)S(0.002)R 62.406 0.00087292 10995000 1379.3 1028.6 1095.9 1217.2 1306.2 1726.3 1122.6 928.8 1337.6 1498.8 TRUE FALSE FALSE 1270.12695 1117.507601 1136.515018 1212.163549 1290.624418 1368.245921 1154.097135 1211.986844 1190.868627 1550.883188 0.818970093 0.72056207 0.732817937 0.781595647 0.832186736 0.882236606 0.744154778 0.781481709 0.767864811 1 10.59887431 -8.754337898 0.7549316 0.995828816 0.785407014 0 0.083715468 0.263452568 0.292285017 0.029728755 0.011313041 1.76E-09 8.754337898 -0.210421802 HLAAVEER ddPTM_HeLa_Curcumin_4h_R1 1 HLAAVEER 8 0 Q92922;F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 Q92922;F8VXC8 SMARCC1;SMARCC2 SWI/SNF complex subunit SMARCC1;SWI/SNF complex subunit SMARCC2 0 0 115.49 0.0077284 2533200 1094.4 689.97 943.13 751.32 914.55 1035.3 831.11 903.79 920.49 891.1 FALSE FALSE TRUE 1007.777085 749.6079324 978.0832275 748.2112369 903.6445886 820.5671098 854.4287098 1179.35141 819.51455 922.0656587 1.092955882 0.812965894 1.060752256 0.811451148 0.980021954 0.889922645 0.926646277 1.279031921 0.888781121 1 9.848725676 HLAESESLLT(ph)SPPK ddPTM_HeLa_Curcumin_4h_R1 2 HLAESESLLTSPPK 14 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 0 HLAESESLLT(0.584)S(0.416)PPK;HLAESESLLT(0.576)S(0.424)PPK ; 116.58 0.0019712 30780000 6150.6 5825.7 5852.8 5414.6 7754.8 8019.2 5048.8 2894.1 6850.7 5239.9 TRUE FALSE FALSE 5663.77352 6329.247549 6069.709917 5392.19582 7662.329075 6355.927525 5190.45574 3776.497767 6099.19535 5421.986135 1.044593877 1.167330087 1.119462456 0.994505645 1.413195992 1.172250789 0.957297863 0.696515571 1.12490058 1 12.40460571 -4.352382586 3.223371325 1.072993512 0.67638261 0.500367175 0.123768873 0.206948147 3.419330791 0.018539917 0.177353831 4.44E-05 4.352382586 -0.396610902 HLAESESLLTS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 2 HLAESESLLTSPPK 14 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 0 HLAESESLLT(0.252)S(0.748)PPK;HLAESESLLT(0.145)S(0.855)PPK ; 110.35 0.0013791 14547200 6233.9 5748.7 5631.9 6129.7 7914.5 7536.9 5547.6 3193 6986.9 5120.7 TRUE FALSE FALSE 5740.480237 6245.592012 5840.623168 6104.336926 7820.124757 5973.661982 5703.250725 4166.531001 6220.45455 5298.643944 1.083386674 1.178715173 1.102286402 1.152056449 1.475872853 1.127394489 1.07636044 0.786339117 1.173971042 1 12.37140747 -8.038621821 0.97695093 1.015987231 1.139072331 0 0.164864174 0.861812289 1.746533981 0.045952014 0.035432026 9.15E-09 8.038621821 0.123085101 HLAGLGLTEAIDK ddPTM_HeLa_Curcumin_4h_R1 1 HLAGLGLTEAIDK 13 0 P50454;E9PKH2 P50454 SERPINH1 Serpin H1 0 0 71.085 0.01801 1356100 1540.2 1313.5 1388.8 1632.8 1439.3 1712.8 1209 773.95 1452.8 1390.5 FALSE FALSE TRUE 1418.291545 1427.033087 1440.27015 1626.043906 1422.137288 1357.545973 1242.921286 1009.923792 1293.431475 1438.819772 0.985732593 0.991808088 1.001008033 1.13012341 0.988405439 0.943513566 0.863847794 0.701911255 0.898953087 1 10.49067017 -4.394224585 1.422920633 1.003286474 0.626645313 0.751103329 0.053188257 0.279690157 0.603610622 0.006356872 0.1388301 4.03E-05 4.394224585 -0.376641161 HLAGLGLTEAIDKNK ddPTM_HeLa_Curcumin_4h_R1 1 HLAGLGLTEAIDKNK 15 1 P50454;E9PKH2 P50454 SERPINH1 Serpin H1 0 0 68.676 0.007289 2633500 4075.4 2987.3 3771.2 3125.6 3385.4 4205.9 2335.3 2424.6 4198 3368.6 FALSE FALSE TRUE 3752.82779 3245.508901 3910.963989 3112.667095 3345.031316 3333.54893 2400.822233 3163.849379 3737.489903 3485.658599 1.076648123 0.931103494 1.122015791 0.892992531 0.959655463 0.956361283 0.68877148 0.907676208 1.07224784 1 11.76721556 -5.338221585 0.934534325 1.032402677 0.797539003 0.474400216 0.084450657 0.412240517 0.599006889 0.012812261 0.066916393 4.59E-06 5.338221585 -0.234863673 HLAPPPLLS(ph)PLLPSIKPTVR ddPTM_HeLa_Curcumin_4h_R1 2 HLAPPPLLSPLLPSIKPTVR 20 1 Q14676;Q14676-3;Q14676-2;H0Y6Z8 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 HLAPPPLLS(1)PLLPSIKPTVR;HLAPPPLLS(1)PLLPSIKPTVR ; 114.06 6.32E-05 38145000 15004.4 11552.5 12403.2 14658.8 13392.4 26240.3 22277.7 8737.6 15001.7 10716.2 TRUE FALSE FALSE 13816.78591 12551.04662 12862.8735 14598.14577 13232.70438 20797.76599 22902.7523 11401.65402 13356.05104 11088.58715 1.246036643 1.131888711 1.160010137 1.316501874 1.193362526 1.875601076 2.065434666 1.028233251 1.204486276 1 13.43678794 -5.32980768 6.434626362 1.141791169 1.696116188 0.405327801 0.261247186 0.142377437 10.91076024 0.0357779 0.080962167 4.68E-06 5.32980768 0.554325019 HLAQAS(ph)QELQ ddPTM_HeLa_Curcumin_4h_R1 1 HLAQASQELQ 10 0 A0A669KBG0;Q8NBP7 A0A669KBG0 PCSK9 Proprotein convertase subtilisin/kexin type 9 1 0 HLAQAS(1)QELQ 96.015 0.015222 10955000 2832.6 2726.3 2890.8 3139 2964.5 3236.5 2364.7 1496.8 3023.2 3184.5 TRUE FALSE FALSE 2608.396721 2961.949224 2997.935591 3126.01165 2929.150274 2565.213417 2431.047118 1953.16743 2691.562524 3295.161138 0.791583966 0.898878416 0.909799389 0.948667309 0.888924745 0.7784789 0.737762742 0.592738063 0.816822732 1 11.6861333 -4.553886419 1.107119691 0.903778766 0.534386813 0.725228339 0.058901841 0.551891412 0.750937853 0.01207569 0.209227086 2.79E-05 4.553886419 -0.369391953 HLDGEEDGS(ph)SDQSQASGTTGGR ddPTM_HeLa_Curcumin_4h_R1 1 HLDGEEDGSSDQSQASGTTGGR 22 0 Q5H909;Q9UNF1-2;Q9UNF1;Q5H907 Q5H909 MAGED2 Melanoma-associated antigen D2 1 0 HLDGEEDGS(0.5)S(0.5)DQSQASGTTGGR 147.26 5.96E-06 16748000 1666.1 1438.8 1335 1256.1 1581.3 1639.5 1229.1 750.58 1586 1279.8 TRUE FALSE FALSE 1534.226427 1563.163461 1384.476274 1250.902591 1562.44403 1299.449219 1263.585238 979.4283868 1412.019768 1324.272955 1.158542445 1.180393706 1.045461413 0.94459574 1.179850441 0.981254819 0.954172804 0.739597062 1.066260368 1 10.3709848 -3.918605886 1.023268211 1.079267668 0.330212628 0.652171323 0.075424956 1.763858251 0.900244554 0.013059875 1.703804684 0.000120613 3.918605886 -0.74905504 HLDGEEDGSS(ph)DQSQASGTTGGR ddPTM_HeLa_Curcumin_4h_R1 1 HLDGEEDGSSDQSQASGTTGGR 22 0 Q5H909;Q9UNF1-2;Q9UNF1;Q5H907 Q5H909 MAGED2 Melanoma-associated antigen D2 1 0 HLDGEEDGS(0.192)S(0.808)DQSQASGTTGGR 167.72 6.23E-09 16282000 2490.6 2040.5 1810.7 1982.6 2309.4 2187.4 1772 1234.1 2215.6 1965.6 TRUE FALSE FALSE 2293.466382 2216.871728 1877.806135 1974.396527 2281.861913 1733.708583 1821.717551 1610.371409 1972.554223 2033.904454 1.127617562 1.089958638 0.923251892 0.970742024 1.121912049 0.852404143 0.895675088 0.791763549 0.969836228 1 10.99003619 -4.633580221 0.707334867 1.056514018 0.708293376 0.491451546 0.07691568 1.09940522 0.517119822 0.013728479 0.274626081 2.32E-05 4.633580221 -0.348220642 HLDKEVGRPMCMTSVQMSNK ddPTM_HeLa_Curcumin_4h_R1 1 HLDKEVGRPMCMTSVQMSNK 20 2 O94915;A0A669KB90;A0A6E1XQM6;F2Z2S2 O94915 FRYL Protein furry homolog-like 0 0 47.68 0.017319 20427000 1251.2 1450.4 1477.6 1464.3 1445 2235.6 1982.8 1407.5 1699.6 1379.6 FALSE FALSE TRUE 1152.1662 1575.766113 1532.361156 1458.241115 1427.769319 1771.91136 2038.432032 1836.640271 1513.158132 1427.540997 0.807098501 1.103832476 1.073427074 1.021505594 1.00015994 1.241233256 1.427932392 1.286576199 1.059975255 1 10.47931646 -5.205658165 0.73230692 0.924418076 1.439147985 0.605974703 0.104376907 0.474749881 0.354120539 0.020005455 0.155309133 6.23E-06 5.205658165 0.514729909 HLDRS(ph)PESDRPR ddPTM_HeLa_Curcumin_4h_R1 1 HLDRSPESDRPR 12 2 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 0 HLDRS(0.926)PES(0.074)DRPR 46.73 0.020457 138930000 936.8 751.29 933.89 744.05 607.34 842.13 666.76 493.54 942.85 785.94 TRUE FALSE FALSE 862.6512915 816.2281599 968.5007849 740.9713182 600.0978672 667.4627452 685.4674911 644.018074 839.4217139 813.2513565 1.060743747 1.003660373 1.190899686 0.911122142 0.73789962 0.820733639 0.842872853 0.791905318 1.032179912 1 9.667557513 -6.008904906 8.433826983 1.038812353 0.805495975 0.818795211 0.057260386 0.046633262 28.73828372 0.00844795 0.014676191 9.80E-07 6.008904906 -0.233316379 HLDRSPES(ph)DRPR ddPTM_HeLa_Curcumin_4h_R1 1 HLDRSPESDRPR 12 2 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 0 HLDRS(0.366)PES(0.634)DRPR 49.189 0.019489 17062000 649.48 534.3 570.66 448.46 636.44 800.37 641.16 513.24 629.1 670.97 TRUE FALSE FALSE 598.0729727 580.4825112 591.8091616 446.6043913 628.8508687 634.36424 659.149224 669.7245133 560.0893039 694.2861576 0.861421427 0.836085388 0.852399483 0.643256943 0.905751702 0.913692766 0.94939128 0.964623169 0.806712474 1 9.439386598 -4.806531302 2.679341912 0.895588012 0.961264144 0.032573582 0.094435786 0.756816166 10.68139349 0.015468231 0.066801995 1.56E-05 4.806531302 0.065676132 HLEFSHDQYR ddPTM_HeLa_Curcumin_4h_R1 1 HLEFSHDQYR 10 0 Q9NR45 Q9NR45 NANS Sialic acid synthase 0 0 167.93 0.00015296 8551400 1598.2 935.36 1217.2 1188.4 1618.2 2037.9 1448.4 1320.6 1551.8 1240.9 FALSE FALSE TRUE 1471.700784 1016.208351 1262.310503 1183.482716 1598.904022 1615.216568 1489.038206 1723.244861 1381.571422 1284.021183 1.146165502 0.791426469 0.98309165 0.921700305 1.24523181 1.257936076 1.159667945 1.342068872 1.075972454 1 10.32645329 -5.741699528 24.81755386 1.031128181 1.245165696 0.598391137 0.102379506 159.4980663 200524.7467 0.016628898 0.03321961 1.81E-06 5.741699528 0.214037515 HLEINPDHPIVETLR ddPTM_HeLa_Curcumin_4h_R1 4 HLEINPDHPIVETLR 15 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 0 ;;; ;;; 168.93 5.49E-05 205473000 14163.5 11922.6 11898.9 11827.1 12261.8 15369.4 11986.6 11855.6 13750.2 12167.7 FALSE FALSE TRUE 13042.44403 12953.13642 12339.8837 11778.16259 12115.58604 12181.61319 12322.91174 15470.31786 12241.83746 12590.52667 1.035893444 1.028800205 0.980092734 0.93547815 0.962277938 0.967522131 0.978744739 1.228726825 0.972305431 1 13.62005101 -4.257935214 24.68435538 1.001316679 1.228726928 0.826202248 0.032794879 105.7488108 744884.5873 0.005346438 0.052754169 5.52E-05 4.257935214 0.227410249 HLEINPDHSIIETLR ddPTM_HeLa_Curcumin_4h_R1 6 HLEINPDHSIIETLR 15 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 ;;;;; ;;;;; 139.77 0.000158 190743700 11153.5 9973.2 10398 10403.9 9795 13497.4 10735.6 11536.1 11476.1 9901.9 FALSE FALSE TRUE 10270.68871 10835.23897 10783.35903 10360.85142 9678.201022 10697.88709 11036.81204 15053.40378 10217.20054 10245.99029 1.002410545 1.057510174 1.052446735 1.011210349 0.944584247 1.044104747 1.077183535 1.469199498 0.997190145 1 13.32277181 -4.193345825 2.315483349 1.007688651 1.635982262 0.948236058 0.031714457 0.116759408 0.624773101 0.004545947 0.157796322 6.41E-05 4.193345825 0.628293611 HLEPEPEEEIIAEDYDDDPVDYEATR ddPTM_HeLa_Curcumin_4h_R1 1 HLEPEPEEEIIAEDYDDDPVDYEATR 26 0 O60828-5;O60828-4;O60828-2;O60828;A0A5H1ZRR1;O60828-10;O60828-9;O60828-8;O60828-7;O60828-6;O60828-3 O60828-5 PQBP1 Polyglutamine-binding protein 1 0 0 140.41 7.38E-08 18352000 1796.2 1625.3 1815.4 1422.2 1863.6 2176.4 1596.4 1613.2 1575.8 1516.7 FALSE FALSE TRUE 1654.028875 1765.78369 1882.680321 1416.315313 1841.377787 1724.990107 1641.190688 2105.057254 1402.938682 1569.405212 1.05392085 1.125129238 1.199613909 0.902453555 1.173296592 1.099136216 1.045740561 1.341308948 0.893930179 1 10.61600218 -1.861758357 1.3258533 1.048562899 199.9999999 0.425405104 0.09824373 641.8675305 2.127307559 0.012287068 387294.6204 0.013748067 1.861758357 198.951437 HLFSS(ph)TENLAAGSWKEPAEGGGLSSDR ddPTM_HeLa_Curcumin_4h_R1 2 HLFSSTENLAAGSWKEPAEGGGLSSDR 27 1 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 1 0 HLFS(0.18)S(0.41)T(0.41)ENLAAGSWKEPAEGGGLSSDR;HLFS(0.107)S(0.447)T(0.447)ENLAAGSWKEPAEGGGLSSDR ; 67.827 0.00019905 121443000 3707.8 3130 3032.5 3467.1 3745.7 5046.5 2698 1395.47 4301 3066.9 TRUE FALSE FALSE 3414.323718 3400.543253 3144.887118 3452.754059 3701.034974 3999.799014 2773.698619 1820.942379 3829.191061 3173.474547 1.075894471 1.071552081 0.990991757 1.088004333 1.166240636 1.260384779 0.874025797 0.573800846 1.20662416 1 11.63184756 -4.413613162 3.523380324 1.061298084 0.577454278 0.751544071 0.092569377 0.092832855 1.896017202 0.012083916 0.090780086 3.86E-05 4.413613162 -0.483843806 HLGVCISVANNR ddPTM_HeLa_Curcumin_4h_R1 1 HLGVCISVANNR 12 0 O43390;B4DT28;O43390-4;O43390-3;O43390-2 O43390 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 0 79.036 0.013663 3288200 1173.5 909.88 1154 1073.1 1456.8 2159.9 1565.4 1330.3 1648.7 1314.5 FALSE FALSE TRUE 1080.616237 988.5259729 1196.768255 1068.659797 1439.428611 1711.912393 1609.320911 1735.902346 1467.841735 1360.178777 0.794466327 0.726761797 0.879860997 0.785675982 1.058264278 1.258593666 1.183168667 1.276231018 1.079153534 1 10.40958057 -5.50901081 3.645598533 0.877010601 1.230208809 0.723674776 0.100218902 0.094055992 2.679591998 0.014994364 0.033600807 3.10E-06 5.50901081 0.353198208 HLIPAANTGESK ddPTM_HeLa_Curcumin_4h_R1 2 HLIPAANTGESK 12 0 P62258;P62258-2 P62258 YWHAE 14-3-3 protein epsilon 0 0 ; ; 141.08 3.34E-05 14263700 14534.1 12945.7 14037.9 12983.1 16302.7 14492 13117 12974.1 12321.5 11257.3 FALSE FALSE TRUE 13383.71065 14064.66862 14558.15692 12929.37937 16108.30095 11486.19584 13485.02772 16929.84336 10969.86228 11648.49034 1.148965253 1.207424157 1.249789157 1.109961806 1.382865975 0.986067337 1.157663124 1.453393777 0.941741115 1 13.50785537 -13.52287874 0.119401512 0.260715412 1.318462304 0.395677813 0.123414671 78.74641801 0.679774159 13.82540639 0.568480191 3.00E-14 13.52287874 1.057746892 HLIVLINK ddPTM_HeLa_Curcumin_4h_R1 2 HLIVLINK 8 0 H3BR35;P15170;P15170-2;P15170-3;Q8IYD1 H3BR35 GSPT1;GSPT2 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A;Eukaryotic peptide chain release factor GTP-binding subunit ERF3B 0 0 ; ; 128.38 3.96E-07 0 19416 13113.7 16040.5 13830 16276.9 22485 17614 16421.3 16379 15828.6 FALSE FALSE TRUE 17879.20311 14247.18979 16634.97504 13772.77512 16082.8086 17821.35754 18108.20143 21428.07878 14582.26468 16378.64267 1.091616898 0.869863888 1.015650404 0.840898443 0.981937815 1.08808513 1.105598418 1.308293929 0.890321925 1 13.99952818 -4.205162519 1.423120617 1.011447304 1.453513162 0.569682123 0.086406439 0.85941234 1.392191172 0.01263972 0.559382598 6.24E-05 4.205162519 0.442065857 HLLAPGPQDIY(ph)DVPPVR ddPTM_HeLa_Curcumin_4h_R1 1 HLLAPGPQDIYDVPPVR 17 0 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4;H3BN62 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 0 HLLAPGPQDIY(1)DVPPVR 102.15 0.0083363 4904800 3097.6 2056.9 2883.7 2974.8 2927.7 4205.3 2579.6 1767.1 2582.1 2835.7 TRUE FALSE FALSE 2852.421691 2234.689271 2990.572459 2962.491066 2892.78909 3333.073377 2651.976633 2305.880655 2298.85009 2934.240364 0.972115893 0.761590393 1.019198187 1.009627944 0.985873252 1.13592377 0.903803474 0.785852681 0.783456638 1 11.51877134 -2.384836671 0.008051732 1.852012594 7.24E-06 0 0.124256084 45544.03629 36.5185326 3827.733321 4604.98873 0.004122525 2.384836671 -1.852005349 HLLIGVSSDR ddPTM_HeLa_Curcumin_4h_R1 2 HLLIGVSSDR 10 0 P36542-2;P36542 P36542-2 ATP5C1 "ATP synthase subunit gamma, mitochondrial" 0 0 ; ; 90.15 0.0062354 5296200 3180.5 2352.8 2563.2 2279.6 3901.4 5293.5 3246.1 2212.7 3980 2623.2 FALSE FALSE TRUE 2928.760069 2556.165548 2658.194447 2270.167619 3854.878353 4195.56843 3337.17683 2887.342044 3543.403957 2714.356005 1.078988925 0.941720815 0.979309436 0.836355885 1.420181563 1.545695709 1.229454362 1.063730048 1.30543081 1 11.40639424 -5.752166373 24.99963404 1.012812274 1.325166821 0.435075387 0.162065862 116.0851279 312958.1883 0.020062785 0.039691664 1.77E-06 5.752166373 0.312354547 HLLNS(ph)PTDPFNR ddPTM_HeLa_Curcumin_4h_R1 2 HLLNSPTDPFNR 12 0 O95155-2;O95155;O95155-4;O95155-3 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 0 HLLNS(0.99)PT(0.01)DPFNR;HLLNS(1)PTDPFNR ; 119.77 0.0016956 17666100 5682.6 4734.7 4993.4 5545.2 4963.8 6462.9 4682.6 3962 5528.4 5334.4 TRUE FALSE FALSE 5232.816214 5143.946371 5178.459797 5522.255432 4904.609927 5122.421688 4813.981153 5169.995561 4921.948351 5519.770003 0.948013452 0.931913172 0.938165864 1.000450278 0.888553314 0.92801361 0.872134374 0.936632425 0.891694463 1 12.43039244 HLLQEARS(ph)PDPGIVPQEAPVGNSLSELSEENFDGK ddPTM_HeLa_Curcumin_4h_R1 1 HLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGK 35 1 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;X6RGP5;A0A0C4DH09;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 HLLQEARS(0.981)PDPGIVPQEAPVGNS(0.012)LS(0.005)ELS(0.002)EENFDGK 49.342 0.0037102 12123000 915.78 495.23 810.6 837.14 644.7 750.76 561.97 315.91 1139.1 716.88 TRUE FALSE FALSE 843.2950467 538.0354745 840.6415491 833.6761365 637.0123736 595.0439132 577.7373657 412.2295047 1014.14358 741.7915266 1.136835642 0.725318981 1.133258495 1.123868508 0.858748517 0.802171354 0.778840611 0.555721507 1.367154441 1 9.534869978 -4.504665773 0.684745752 1.050840226 0.376880125 0.5371898 0.158178434 1.152604444 0.454435064 0.021749409 0.562174294 3.13E-05 4.504665773 -0.673960101 SEENIS(ph)PDTIR ddPTM_HeLa_Curcumin_4h_R1 1 SEENISPDTIR 11 0 E9PML3;Q8N157-3;Q8N157-2;Q8N157 E9PML3 AHI1 Jouberin 1 0 SEENIS(0.998)PDT(0.002)IR 117.95 0.0037247 0 1167.1 1134.5 1102.2 1260 1140.1 1208.1 813.36 422.03 1697.6 1213.6 TRUE FALSE FALSE 1074.722803 1232.561125 1143.048502 1254.786454 1126.505052 957.5264419 836.1806926 550.7050042 1511.377527 1255.77251 0.855826032 0.98151625 0.910235327 0.999214781 0.897061405 0.762499923 0.665869563 0.438538828 1.203544046 1 10.29435942 -4.474058216 1.050339642 0.93819588 0.299166485 0.770288172 0.095760601 0.315685617 0.345273571 0.009271373 0.205747136 3.36E-05 4.474058216 -0.639029395 down GGFDS(ph)PFYR ddPTM_HeLa_Curcumin_4h_R1 3 GGFDSPFYR 9 0 A0A2R8YEH9;A0A2R8Y6S1;A0A2R8YFV7;A0A2R8Y5N2;A0A2R8Y5S3;Q92574-2;Q92574 A0A2R8YEH9 TSC1 Hamartin 1 0 GGFDS(1)PFYR;GGFDS(1)PFYR;GGFDS(1)PFYR ;; 120.63 0.0060719 89941000 9791.8 8323 7920.5 9307.2 9059.1 8637 5884.9 2618.29 8623.8 7936.7 TRUE FALSE FALSE 9016.768698 9042.403033 8214.040698 9268.689272 8951.076149 6845.588841 6050.014456 3416.594568 7677.790716 8212.499734 1.097932297 1.101053677 1.000187636 1.128607558 1.089933204 0.833557268 0.736683671 0.416023705 0.934890833 1 13.0036057 -4.473648573 1.208965525 1.057022734 0.273294733 0.897754676 0.067303401 0.205132472 0.321531682 0.00915608 0.181661482 3.36E-05 4.473648573 -0.783728001 down HLPS(ph)PPLTQEVDLHSIAGPPVPPR ddPTM_HeLa_Curcumin_4h_R1 1 HLPSPPLTQEVDLHSIAGPPVPPR 24 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 0 HLPS(0.987)PPLT(0.013)QEVDLHSIAGPPVPPR 73.383 0.00026236 16873000 1681.5 1170.7 1550.1 1292.9 1336.6 1584.6 1075.6 1217.6 1465.6 1587.4 TRUE FALSE FALSE 1548.407501 1271.890091 1607.54807 1287.550322 1320.661918 1255.936098 1105.778441 1588.840635 1304.827347 1642.562032 0.942678249 0.774333064 0.978683324 0.783867091 0.804025597 0.764620193 0.673203459 0.967294144 0.79438543 1 10.68173214 -7.135517447 0.597961006 0.992865764 0.786005013 0 0.107652133 0.442908231 0.346690867 0.024822077 0.032510834 7.32E-08 7.135517447 -0.206860751 HLPS(ph)PPTLDSIITEYLR ddPTM_HeLa_Curcumin_4h_R1 2 HLPSPPTLDSIITEYLR 17 0 Q9Y4B6-3;Q9Y4B6-2;Q9Y4B6 Q9Y4B6-3 VPRBP Protein VPRBP 1 0 HLPS(0.915)PPT(0.008)LDS(0.052)IIT(0.025)EYLR;HLPS(0.509)PPT(0.051)LDS(0.417)IIT(0.024)EYLR ; 120.59 0.00061983 214853000 1735.8 1511.33 1596.25 1506.03 1576.82 2262.5 1347.08 1279.49 1942.68 1763.87 TRUE FALSE FALSE 1598.409598 1641.962631 1655.408429 1499.798447 1558.017451 1793.231996 1384.875439 1669.600611 1729.572864 1825.164351 0.875762009 0.899624535 0.906991432 0.821733367 0.853631318 0.982504395 0.758767526 0.91476727 0.94762582 1 10.83381067 -9.525659348 0.43654736 1.048098645 0.868125206 0.289406255 0.058404407 1.747826249 0.377150533 0.145812413 0.015757723 2.98E-10 9.525659348 -0.179973439 HLQLAIR ddPTM_HeLa_Curcumin_4h_R1 2 HLQLAIR 7 0 Q93077;Q7L7L0;P04908;A0A3B3IS11;Q96QV6;A0A0U1RR32;A0A0U1RRH7;Q99878;Q96KK5;Q16777;Q6FI13;P20671;P0C0S8;Q9BTM1;Q9BTM1-2;H0YFX9;P16104;A0A494C189;P0C0S5;Q71UI9-4;C9J0D1;Q71UI9-2;Q71UI9;C9J386;Q71UI9-3 Q93077;A0A0U1RR32;P16104;A0A494C189;C9J0D1 HIST1H2AC;HIST3H2A;HIST1H2AB;HIST1H2AA;HIST1H2AJ;HIST1H2AH;HIST2H2AC;HIST2H2AA3;HIST1H2AD;HIST1H2AG;H2AFJ;H2AFX;H2AFZ;H2AFV Histone H2A type 1-C;Histone H2A type 3;Histone H2A type 1-B/E;Histone H2A type 1-A;Histone H2A type 1-J;Histone H2A type 1-H;Histone H2A type 2-C;Histone H2A type 2-A;Histone H2A type 1-D;Histone H2A type 1;Histone H2A.J;Histone H2A;Histone H2AX;Histone H2A.Z;Histone H2A.V 0 0 ; ; 148.07 0.00042148 58124000 6454.6 2788.5 3968.4 3505.1 3388.8 6752.7 4182.3 4169.1 4767.8 4362.6 FALSE FALSE TRUE 5943.711599 3029.525515 4115.472395 3490.596825 3348.390773 5352.113901 4299.644082 5440.239398 4244.784268 4514.200025 1.316669967 0.671110163 0.911672582 0.773248151 0.741746213 1.185617357 0.952470883 1.205139198 0.940318162 1 12.14025463 -7.27410006 24.98495307 1.14953859 0.918760331 0.111087605 0.190346658 841.8980236 1661422.434 0.033945415 0.038952839 5.32E-08 7.27410006 -0.230778258 HLQQGSES(ph)PMMIGELR ddPTM_HeLa_Curcumin_4h_R1 1 HLQQGSESPMMIGELR 16 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 0 HLQQGS(0.137)ES(0.863)PMMIGELR 91.845 0.0021784 8147400 755.19 658.86 685.74 722.28 767.93 960.85 731.1 577.84 884.18 773.18 TRUE FALSE FALSE 695.4159146 715.8089226 711.1541276 719.2913967 758.7729363 761.558879 751.6126983 754.020756 787.1876661 800.0479474 0.869217797 0.89470753 0.888889385 0.899060361 0.948409328 0.951891548 0.939459567 0.942469459 0.983925612 1 9.643942654 -3.25541548 13.90253571 0.930671869 42.18781448 0 0.040544728 0 0 0.006954744 0 0.000555373 3.25541548 41.25714261 HLS(ph)MVPGSYIK ddPTM_HeLa_Curcumin_4h_R1 1 HLSMVPGSYIK 11 0 Q8WTQ4 Q8WTQ4 C16orf78 Uncharacterized protein C16orf78 1 0 HLS(0.978)MVPGS(0.022)YIK 98.249 0.014178 5939400 5089.8 3939.2 3852 5572.3 5310.7 662.66 1742.7 1642.8 4703.4 4677.9 TRUE FALSE FALSE 4686.936959 4279.686895 3994.758509 5549.243299 5247.373371 525.2168463 1791.595472 2143.682157 4187.448787 4840.456677 0.968284043 0.884149406 0.825285459 1.146429701 1.084065765 0.108505639 0.37012943 0.44286775 0.865093744 1 12.24092745 -5.266864757 24.99999183 0.982784013 0.313463779 0.860761531 0.121611866 101.125558 465984.7084 0.016274408 0.037391515 5.41E-06 5.266864757 -0.669320235 NAS(ph)AS(ph)FQELEDK ddPTM_HeLa_Curcumin_4h_R1 1 NASASFQELEDK 12 0 F2Z3H0;F2Z3N9;H7C3L7;Q99543-2;Q99543 F2Z3H0 DNAJC2 "DnaJ homolog subfamily C member 2;DnaJ homolog subfamily C member 2, N-terminally processed" 2 0 NAS(1)AS(1)FQELEDK 112.62 0.011456 3959700 3479.1 3288.3 3488.3 3695.6 4308.8 4422.3 2520 1177.2 3008.8 3446.1 TRUE FALSE FALSE 3203.725564 3572.526 3617.579467 3680.308586 4257.420374 3505.06513 2590.704418 1536.122861 2678.742168 3565.851718 0.898446098 1.001871721 1.014506422 1.032098045 1.193942068 0.982953136 0.72653173 0.430787083 0.751220852 1 11.800031 -4.473546455 2.469466392 0.983823526 0.413760645 0.732948319 0.105465183 0.118433987 1.175512716 0.012730459 0.115592013 3.36E-05 4.473546455 -0.570062881 down HLTASEAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 HLTASEAKK 9 1 P39748-2;P39748 P39748-2 FEN1 Flap endonuclease 1 0 1 HLTASEAK(1)K 83.647 0.0075074 1666900 1060.6 941.36 947.01 792.56 1929.1 3892.7 1918.5 1228.8 1601.3 1066.5 FALSE TRUE FALSE 976.6523909 1022.726964 982.1070237 789.2805967 1906.096742 3085.31014 1972.327947 1603.455463 1425.641396 1103.560796 0.885000985 0.926751809 0.889943742 0.71521261 1.727224046 2.795777226 1.787239955 1.452983351 1.291855783 1 10.1079504 -5.640248331 4.973352553 0.925221603 2.028925113 0.66965169 0.343421781 0.081279371 3.209433983 0.045779629 0.093077275 2.29E-06 5.640248331 1.103703509 HLTGEFEK ddPTM_HeLa_Curcumin_4h_R1 3 HLTGEFEK 8 0 F5H018;B5MDF5;J3KQE5;P62826;H0YFC6 F5H018 RAN GTP-binding nuclear protein Ran 0 0 ;; ;; 133.23 0.0036641 25452200 17786.4 15365.8 14783.9 13704.5 24344.6 30270.6 18995.9 16790.4 21973.4 15747.9 FALSE FALSE TRUE 16378.58767 16693.95128 15331.80434 13647.79441 24054.30654 23992.13634 19528.87383 21909.71567 19562.97299 16295.13835 1.005121118 1.024474351 0.940882121 0.837537805 1.47616461 1.472349349 1.198447869 1.344555363 1.200540466 1 13.99215398 -5.757504406 24.9999869 0.988879568 1.367524943 0.72761594 0.111161353 31.7910849 201974.7625 0.01311374 0.025463839 1.75E-06 5.757504406 0.378645375 HLTGEFEKK ddPTM_HeLa_Curcumin_4h_R1 1 HLTGEFEKK 9 1 F5H018;B5MDF5;J3KQE5;P62826;H0YFC6 F5H018 RAN GTP-binding nuclear protein Ran 0 0 31.53 0.019435 5100300 4327.3 3721.4 2955.2 3092.7 5635 8466.5 5102.8 4564 6726.1 3596.1 FALSE FALSE TRUE 3984.789639 4043.061234 3064.722312 3079.903227 5567.806305 6710.452463 5245.970835 5955.54259 5988.263658 3721.064207 1.070873658 1.086533585 0.823614466 0.82769419 1.496294069 1.803369168 1.409803901 1.600494444 1.609287914 1 11.86149957 -5.667068966 5.903696699 1.008878951 1.59321735 0.537391131 0.227684609 0.061510692 3.170922281 0.018485375 0.037224403 2.15E-06 5.667068966 0.584338398 HLTT(ph)EAQAAET(ph)T(ph)TST(ph)TS(ph)SLAPPPTTK ddPTM_HeLa_Curcumin_4h_R1 1 HLTTEAQAAETTTSTTSSLAPPPTTK 26 0 P26992 P26992 CNTFR Ciliary neurotrophic factor receptor subunit alpha 5 0 HLT(0.161)T(0.707)EAQAAET(0.608)T(0.613)T(0.613)S(0.293)T(0.489)T(0.489)S(0.501)S(0.501)LAPPPT(0.013)T(0.014)K 44.632 0.0093298 8261500 1862.8 1279.3 1375.8 1659.3 1935.8 2403.8 1633.5 1143.2 1626.1 1472.2 TRUE FALSE FALSE 1715.357414 1389.876992 1426.788358 1652.434256 1912.716849 1905.224784 1679.331614 1491.756417 1447.720898 1523.35884 1.126036341 0.912376621 0.936606872 1.084730802 1.255591787 1.250673665 1.102387415 0.979254774 0.950347915 1 10.57304011 -5.993156639 24.62087158 1.03802867 1.153569179 0.318378667 0.097876065 173.9055314 625664.7323 0.015457187 0.027967477 1.02E-06 5.993156639 0.11554051 HLTVEELFGTS(ph)LPK ddPTM_HeLa_Curcumin_4h_R1 1 HLTVEELFGTSLPK 14 0 Q9NPI6-2;Q9NPI6;A0A087WT55 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 0 HLTVEELFGT(0.316)S(0.684)LPK 76.158 0.011287 5433600 2584.3 2133 2065.5 1837.6 2679.1 3138.5 2179.4 1347.1 2478 2088.9 TRUE FALSE FALSE 2379.749928 2317.367016 2142.049247 1829.996498 2647.153482 2487.539722 2240.548098 1757.824589 2206.1696 2161.48912 1.100977056 1.072115975 0.991006259 0.846636923 1.22468971 1.150845359 1.036576163 0.813247022 1.020671157 1 11.07780986 -6.77089706 24.92169256 1.050848371 1.020352383 0.020024601 0.118083732 980.6552881 2584092.956 0.019658186 0.026026357 1.69E-07 6.77089706 -0.030495988 HLVYESDQNK(ac)DGK ddPTM_HeLa_Curcumin_4h_R1 3 HLVYESDQNKDGK 13 1 O43852-2;O43852;O43852-4;O43852-3;O43852-9;O43852-5;H0Y875;O43852-15 O43852-2 CALU Calumenin 0 1 ;; HLVYESDQNK(1)DGK;HLVYESDQNK(1)DGK;HLVYESDQNK(1)DGK 120.59 0.001312 7634000 2234.65 3953.66 2551.99 2525.35 5396.06 6352.2 3953.91 3234.07 7913.68 2660.12 FALSE TRUE FALSE 2057.775095 4295.396753 2646.568994 2514.900771 5331.715509 5034.682116 4064.846073 4220.123055 7045.569103 2752.558972 0.747586197 1.560510346 0.961494021 0.913659179 1.93700319 1.829091463 1.476751675 1.533163539 2.55964329 1 11.42655776 -5.771995872 24.94312915 0.943448826 1.688133763 0 0.564457816 90.59202308 214053.2267 0.038100311 0.069589594 1.69E-06 5.771995872 0.744684937 HMCAGRTAAGGSFQRRALWVLAFCTSFGLLLS(ph)WS(ph)SNR ddPTM_HeLa_Curcumin_4h_R1 1 HMCAGRTAAGGSFQRRALWVLAFCTSFGLLLSWSSNR 37 3 Q16515-2 Q16515-2 2 0 HMCAGRT(0.007)AAGGS(0.006)FQRRALWVLAFCT(0.016)S(0.016)FGLLLS(0.858)WS(0.858)S(0.24)NR 40.545 0.012528 54444000 6139.6 3970.3 4292.1 4641.1 3787.7 6241.5 5336.7 5236.8 7068.2 5576 TRUE FALSE FALSE 5653.644182 4313.475041 4451.169002 4621.896358 3742.534151 4946.942544 5486.433439 6833.476213 6292.836144 5769.765585 0.979874156 0.747599704 0.771464444 0.801054443 0.648645789 0.85739056 0.950893647 1.184359418 1.090657159 1 12.49429699 -7.372017706 7.667067352 0.991069681 0.842976415 0.233199264 0.138624768 0.33855065 21.16737514 0.023882216 0.027244835 4.25E-08 7.372017706 -0.148093266 GYVLGETSNLPS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 2 GYVLGETSNLPSPGK 15 0 B1AKT1;Q9H040 B1AKT1 SPRTN SprT-like domain-containing protein Spartan 1 0 GYVLGET(0.005)SNLPS(0.995)PGK;GYVLGETSNLPS(1)PGK ; 171.46 0.00015227 36117000 4143.8 3279.6 3117.7 3444.1 3742.2 4243.8 2368.92 1056.26 3887.4 2963.9 TRUE FALSE FALSE 3815.813857 3563.07401 3233.244705 3429.849227 3697.576709 3363.588043 2435.38552 1378.308812 3460.961946 3066.895304 1.244194366 1.161785342 1.054240326 1.118345717 1.205641648 1.096740419 0.794088248 0.449415019 1.128490412 1 11.5825632 -4.473217512 2.092898359 1.123892274 0.398619569 0.912449754 0.066824767 0.131235168 0.858048636 0.013755571 0.151079046 3.36E-05 4.473217512 -0.725272705 down HMDPPPAPVQDRS(ph)PSPR ddPTM_HeLa_Curcumin_4h_R1 6 HMDPPPAPVQDRSPSPR 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 HMDPPPAPVQDRS(0.928)PS(0.072)PR;HMDPPPAPVQDRS(0.505)PS(0.495)PR;HMDPPPAPVQDRS(0.741)PS(0.259)PR;HMDPPPAPVQDRS(0.77)PS(0.23)PR;HMDPPPAPVQDRS(0.879)PS(0.121)PR;HMDPPPAPVQDRS(0.5)PS(0.5)PR ;;;;; 96.247 0.00095661 56420200 13890.9 12002 12894.6 13801.9 12448.4 10929.22 8824.32 6276.98 14462.3 12486.4 TRUE FALSE FALSE 12791.42061 13039.3994 13372.48522 13744.79139 12299.96096 8662.376574 9071.90667 8190.802306 12875.82187 12920.30147 0.990024934 1.009217891 1.034997926 1.063813521 0.951987149 0.670446939 0.702143575 0.633948234 0.996557387 1 13.65735211 -5.304647062 3.978902714 1.003973155 0.668639515 0.969265788 0.027689341 0.026802588 0.914013809 0.00412859 0.01004657 4.96E-06 5.304647062 -0.33533364 HMGIGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 4 HMGIGKR 7 1 J3QR09;J3KTE4;P84098 J3QR09 RPL19 Ribosomal protein L19;60S ribosomal protein L19 0 1 ;;; HMGIGK(1)R;HMGIGK(1)R;HMGIGK(1)R;HMGIGK(1)R 89.903 0.01012 12453200 2215.75 1653.12 2037.85 2066.41 1447.74 1779.27 1301.163 1511.56 1826.923 1780.32 FALSE TRUE FALSE 2040.371049 1796.008327 2113.374514 2057.859743 1430.476646 1410.229345 1337.670132 1972.427686 1626.514118 1842.185987 1.107581462 0.974933225 1.147210177 1.117074908 0.776510437 0.765519527 0.726131965 1.070699538 0.882926115 1 10.84720301 -5.759414294 24.99991275 1.057838852 0.822016825 0.4240746 0.114491676 29.64733302 365990.3267 0.014394626 0.027680906 1.74E-06 5.759414294 -0.235822027 HNDDEQYAWESSAGGSFTVR ddPTM_HeLa_Curcumin_4h_R1 3 HNDDEQYAWESSAGGSFTVR 20 0 P08238;P07900;P07900-2;Q14568 P08238;P07900 HSP90AB1;HSP90AA1;HSP90AA2P Heat shock protein HSP 90-beta;Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2 0 0 ;; ;; 127.07 5.65E-05 13883200 5699 4648.5 4163.8 4920.3 5158.49 5185.7 5067.78 4298.11 5234.7 4506.5 FALSE FALSE TRUE 5247.918136 5050.295627 4318.114091 4899.941102 5096.978376 4110.127365 5209.968268 5608.583953 4660.466507 4663.10054 1.125413894 1.083033828 0.926017797 1.050790362 1.093044924 0.881415129 1.11727556 1.202758531 0.999435133 1 12.18707382 -4.525362429 24.9989286 1.043309203 1.181387847 0.354352569 0.074211271 60.64389642 610410.2511 0.010854561 0.041146747 2.98E-05 4.525362429 0.138078644 HNGPNDASDGTVR ddPTM_HeLa_Curcumin_4h_R1 2 HNGPNDASDGTVR 13 0 P31942;P31942-2 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 0 ; ; 129.76 0.00023398 3600500 864.35 663.6 757.06 778.17 719.79 1342.55 803.71 848.74 1028.9 755.25 FALSE FALSE TRUE 795.9357854 720.9586271 785.1173096 774.9501387 711.2069744 1064.089996 826.2599395 1107.516919 916.0322442 781.4948813 1.018478565 0.922537875 1.004635255 0.991625355 0.910059671 1.361608402 1.05728132 1.417177445 1.172153863 1 9.610092614 -5.264122199 24.99914311 0.99496129 1.256548285 0.566082758 0.110036592 101.3474697 944385.943 0.011838552 0.027625434 5.44E-06 5.264122199 0.261586995 HNGS(ph)LSPGLEAR ddPTM_HeLa_Curcumin_4h_R1 1 HNGSLSPGLEAR 12 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 HNGS(0.691)LS(0.309)PGLEAR 65.467 0.020403 90689000 3318.7 3295.5 3042.5 3264.4 3717.5 3836.3 3623.7 4554.7 3862.9 3065.8 TRUE FALSE FALSE 3056.021393 3580.348336 3155.257726 3250.892778 3673.17124 3040.608136 3725.371269 5943.407063 3439.149534 3172.336322 0.963334616 1.128615623 0.994616398 1.024762966 1.157875732 0.958475971 1.174330491 1.873511021 1.084106219 1 11.63133001 -4.260232912 2.714667721 1.007881432 2.043685314 0.926127253 0.06986807 0.076609575 0.744626241 0.009426308 0.177672563 5.49E-05 4.260232912 1.035803882 HNGVGGS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 2 HNGVGGSPPK 10 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 0 HNGVGGS(1)PPK;HNGVGGS(1)PPK ; 88.163 0.010304 55347000 8680.8 8029.7 8695.2 8509 8202 9086 6886.5 6187.9 8354.3 7704.2 TRUE FALSE FALSE 7993.70552 8723.751488 9017.451761 8473.792013 8104.196507 7201.46118 7079.716656 8074.562224 7437.854191 7971.920377 1.002732735 1.094309912 1.13115176 1.062954923 1.016592756 0.903353375 0.888081707 1.012875423 0.933006583 1 12.96071159 -5.304567413 8.15323341 1.024159297 0.930157868 0.353859732 0.060505592 0.270718236 47.83090748 0.008644696 0.019490149 4.96E-06 5.304567413 -0.094001429 HNIQTHTNY(ph)LAMLCMIS(ph)SHV ddPTM_HeLa_Curcumin_4h_R1 1 HNIQTHTNYLAMLCMISSHV 20 0 Q8WUE3 Q8WUE3 CCNE2 2 0 HNIQT(0.005)HT(0.036)NY(0.959)LAMLCMIS(0.5)S(0.5)HV 47.942 0.012686 28437000 2373.6 4012.6 3430.8 3115.1 2154.3 3042.9 2709 1795.9 3467.9 5072.6 TRUE FALSE FALSE 2185.727055 4359.431264 3557.948466 3102.210542 2128.61138 2411.768239 2785.007249 2343.461643 3087.480046 5248.872472 0.416418396 0.830546234 0.67785005 0.591024179 0.405536883 0.459483108 0.530591525 0.446469533 0.588217767 1 12.35779183 -9.455821943 0.869431618 1.040610233 0.53853464 0.071474935 0.177363597 0.392305606 0.45692571 0.140587364 0.025319432 3.50E-10 9.455821943 -0.502075593 HNIVFGDYTWTEFDEPFLTR ddPTM_HeLa_Curcumin_4h_R1 2 HNIVFGDYTWTEFDEPFLTR 20 0 Q15645;H0YAL2;Q15645-2 Q15645 TRIP13 Pachytene checkpoint protein 2 homolog 0 0 ; ; 115.46 0.00011524 38625000 1847.06 1381.01 1745.44 1587.86 1610.32 3208.8 2268.9 1990.82 2180.2 1644.03 FALSE FALSE TRUE 1700.863252 1500.378351 1810.127542 1581.289856 1591.117986 2543.258709 2332.559228 2597.811853 1941.037515 1701.15992 0.999825608 0.881973725 1.064054896 0.929536275 0.935313586 1.495014478 1.371158114 1.527082682 1.141008257 1 10.73230305 -5.2605937 24.99994151 0.98663579 1.455092418 0.884493949 0.078004476 12.60131023 372511.7003 0.007999268 0.019168472 5.49E-06 5.2605937 0.468456627 HNKPEVEVR ddPTM_HeLa_Curcumin_4h_R1 2 HNKPEVEVR 9 1 H7C0A3;F8WCF6;P59998;P59998-3;F8WDD7;A0A0A6YYG9;P59998-2;F8WE39 H7C0A3 ARPC4-TTLL3;ARPC4 Actin-related protein 2/3 complex subunit 4 0 0 ; ; 59.35 0.018028 5350600 10519.7 8076.9 9746.8 9519.4 9845.2 10693.1 8516.8 7059.7 9621.1 10685.2 FALSE FALSE TRUE 9687.054645 8775.031246 10108.02498 9480.011245 9727.80242 8475.230524 8755.758486 9212.170031 8565.689401 11056.5099 0.876140367 0.793652909 0.914214799 0.85741444 0.879825777 0.766537596 0.791909794 0.833189687 0.7747191 1 13.43260844 -13.52287875 0.124420628 1.586484564 0.755045952 0 0.082236796 32.16276135 0.2867368 4.647429513 0.169316079 3.00E-14 13.52287875 -0.831438612 HNMSGGEFQGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 4 HNMSGGEFQGKR 12 1 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 0 1 ;;; HNMSGGEFQGK(1)R;HNMSGGEFQGK(1)R;HNMSGGEFQGK(1)R;HNMSGGEFQGK(1)R 145.81 1.75E-05 7839380 3463.49 2819.18 3455.41 2870.94 2859.84 4664.44 2375.66 2786.75 3302.96 3109.95 FALSE TRUE FALSE 3189.351112 3062.857357 3583.470534 2859.060811 2825.738276 3696.982565 2442.314626 3636.417246 2940.633552 3218.020531 0.991090977 0.951783038 1.113563602 0.888453254 0.878098275 1.14883747 0.758949361 1.130016795 0.913801986 1 11.65195782 HNPT(ph)GAVLFMGQINKP ddPTM_HeLa_Curcumin_4h_R1 1 HNPTGAVLFMGQINKP 16 1 P07093-2;P07093;P07093-3 P07093-2 SERPINE2 Glia-derived nexin 1 0 HNPT(1)GAVLFMGQINKP 67.115 0.015308 5460000 2137 1445.7 1768.8 1649.4 2178.7 2679.7 1486.6 1536.5 1966.5 2033.9 TRUE FALSE FALSE 1967.854195 1570.659866 1834.353284 1642.57522 2152.720425 2123.900014 1528.309995 2004.971777 1750.77987 2104.577874 0.935035106 0.746306367 0.871601525 0.780477283 1.022875158 1.009181005 0.726183628 0.952671698 0.831891227 1 11.03931518 -7.662814014 2.847051686 0.975838564 0.873371036 0 0.107804012 0.303074635 5.180969889 0.018372834 0.018907245 2.17E-08 7.662814014 -0.102467528 HNS(ph)SDGFFNNGPLR ddPTM_HeLa_Curcumin_4h_R1 1 HNSSDGFFNNGPLR 14 0 Q9HC44 Q9HC44 GPBP1L1 Vasculin-like protein 1 1 0 HNS(0.902)S(0.098)DGFFNNGPLR 106.87 0.0016291 9287600 3010.5 2651.4 2590.3 2750.4 3343 3054.9 2292.8 2244.1 3289.2 3019.8 TRUE FALSE FALSE 2772.215748 2880.575202 2686.298797 2739.019574 3303.136908 2421.279304 2357.129797 2928.315759 2928.382989 3124.737825 0.887183471 0.921861405 0.859687739 0.876559803 1.057092496 0.774874386 0.754344822 0.937139665 0.937161181 1 11.60951943 -13.52287875 0.143153239 1.440805354 0.832583643 0.14734833 0.081092183 73.63168605 0.728695169 9.160983939 0.214633829 3.00E-14 13.52287875 -0.608221711 DT(ph)GKTPVEPEVAIHR ddPTM_HeLa_Curcumin_4h_R1 1 DTGKTPVEPEVAIHR 15 1 P60866;P60866-2;E5RIP1;E5RJX2 P60866 RPS20 40S ribosomal protein S20 1 0 DT(0.5)GKT(0.5)PVEPEVAIHR 96.096 0.00182 15090000 6045.8 4987.3 5446.8 5373.2 5434 7894 6002.7 16077 6796.3 5288.5 TRUE FALSE FALSE 5567.268551 5418.379989 5648.663199 5350.967122 5369.203099 6256.695416 6171.119607 20978.80329 6050.762894 5472.274981 1.017359064 0.990151264 1.032233069 0.97783228 0.981164711 1.143344484 1.127706416 3.83365298 1.105712508 1 12.41792501 -4.260121823 5.110056451 1.015383178 3.966064585 0.995971174 0.05329481 0.00632339 0.534536512 0.006853078 0.06548582 5.49E-05 4.260121823 2.950681407 up HNS(ph)WSSSSR ddPTM_HeLa_Curcumin_4h_R1 3 HNSWSSSSR 9 0 H3BQ37;H3BPW9;Q96F86 H3BQ37 EDC3 Enhancer of mRNA-decapping protein 3 1 0 HNS(0.999)WS(0.001)SSSR;HNS(0.976)WS(0.024)SSSR;HNS(0.998)WS(0.001)SSSR ;; 124.39 0.0050996 82255000 6932.79 6729.96 4729.95 4851.34 10050.9 15486 6775.4 5043.55 9277.9 6199.7 TRUE FALSE FALSE 6384.052356 7311.667754 4905.246108 4831.266441 9931.049582 12274.02904 6965.499489 6581.305177 8260.137582 6415.139114 0.995154157 1.139752019 0.764635968 0.753103924 1.548064571 1.913291173 1.085790872 1.025902176 1.287600695 1 12.64726484 -5.754784771 24.99998258 0.974784133 1.408444916 0.342622246 0.272806168 125.00824 469625.5521 0.037698479 0.074027339 1.76E-06 5.754784771 0.433660783 HNST(ph)TSSTSSGGYR ddPTM_HeLa_Curcumin_4h_R1 1 HNSTTSSTSSGGYR 14 0 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0 A0A0A0MRT6 ABI1 Abl interactor 1 1 0 HNS(0.226)T(0.696)T(0.074)S(0.001)S(0.003)TSSGGYR 109.67 0.0087608 3304100 253.13 73.383 196.42 185.62 448.83 537.09 343.43 206.41 214.21 166.71 TRUE FALSE FALSE 233.0944934 79.72589953 203.699498 184.8519536 443.4779954 425.6914797 353.0657215 269.3434588 190.7116989 172.5031601 1.351247671 0.462170661 1.180845023 1.071585897 2.570839834 2.467731487 2.046720311 1.561382752 1.105554813 1 7.430478981 -5.773640988 24.99939009 1.106443208 2.175319621 0.729556909 0.335930911 93.75965427 192100.4997 0.051787833 0.094374191 1.68E-06 5.773640988 1.068876413 HNYYESFS(ph)LSPAAVADNVER ddPTM_HeLa_Curcumin_4h_R1 1 HNYYESFSLSPAAVADNVER 20 0 B2WTI3;B2WTI4;K7EJU9;Q6NYC1-2;Q6NYC1;Q6NYC1-3 B2WTI3 JMJD6 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 1 0 HNYYESFS(0.717)LS(0.283)PAAVADNVER 72.271 0.0026232 3291200 696.94 795.9 751.85 924.25 1053.8 1089.6 664.02 681.9 1120.2 827.8 TRUE FALSE FALSE 641.7764636 864.6940495 779.7142224 920.4256984 1041.234123 863.6046777 682.6506141 889.8081709 997.3168626 856.5659884 0.749243459 1.009489124 0.910279223 1.07455317 1.215591253 1.008217335 0.796962083 1.038808665 1.164319943 1 9.742420583 -6.792412596 2.126134922 0.88368426 1.01726351 0 0.147592036 0.442361835 4.09857061 0.023786298 0.033563557 1.61E-07 6.792412596 0.13357925 HPDVEVDGFSELR ddPTM_HeLa_Curcumin_4h_R1 2 HPDVEVDGFSELR 13 0 P09874;Q5VX84;Q5VX85 P09874 PARP1 Poly [ADP-ribose] polymerase 1 0 0 ; ; 201.38 6.86E-09 43752000 4886.1 3620.2 3382.8 4484.9 4864.3 3346 3235 2963.7 4182.3 3556 FALSE FALSE TRUE 4499.360029 3933.113957 3508.169544 4466.342672 4806.296399 2652.001883 3325.765393 3867.318487 3723.512154 3679.570735 1.222794818 1.068905652 0.953418156 1.213821664 1.306211171 0.720736758 0.903846028 1.051024363 1.011941996 1 11.84532175 -5.258122207 24.99806664 1.112952348 0.89306676 0.379699599 0.128337846 250.361318 1886698.016 0.019366183 0.0472266 5.52E-06 5.258122207 -0.219885588 KFELLPTPPLS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 KFELLPTPPLSPSR 14 1 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1;P04198 H0YBT0 MYC;MYCN Myc proto-oncogene protein;N-myc proto-oncogene protein 1 0 KFELLPT(0.002)PPLS(0.897)PS(0.101)R;KFELLPT(0.002)PPLS(0.867)PS(0.131)R ; 92.474 0.0040305 41176000 9861.6 7801.9 8696 8567.9 9802.7 11188.6 5926 2332.3 8781.9 8461.4 TRUE FALSE FALSE 9081.043954 8476.261471 9018.28141 8532.4483 9685.809205 8867.958238 6092.267611 3043.407533 7818.547541 8755.43302 1.037189587 0.968114478 1.030021175 0.974531846 1.106262727 1.012852045 0.695827105 0.347602172 0.892993816 1 13.09596282 -4.470228408 2.21710892 1.019340268 0.305742893 0.931190746 0.056116589 0.050410991 0.380433815 0.005681069 0.05886543 3.39E-05 4.470228408 -0.713597375 down HPHDIIDDINSGAVECPAS ddPTM_HeLa_Curcumin_4h_R1 1 HPHDIIDDINSGAVECPAS 19 0 P30050;P30050-2 P30050 RPL12 60S ribosomal protein L12 0 0 112.5 0.0003204 18038000 1569.9 1320.6 1582.9 1342.6 1564.7 2209.7 1528 1083.5 1656 1819.3 FALSE FALSE TRUE 1445.640758 1434.74678 1641.563666 1337.044677 1546.041974 1751.383312 1570.871568 1413.854162 1474.340943 1882.52054 0.767928279 0.762141368 0.872003058 0.710241747 0.821261677 0.93033955 0.834451224 0.751043153 0.783173895 1 10.87844989 -9.309815053 0.973275582 1.002993747 0.807124994 0 0.08944696 0.3265637 0.540918908 0.045476662 0.011412073 4.90E-10 9.309815053 -0.195868753 HPPDDDLSQDS(ph)PEQEASKSPR ddPTM_HeLa_Curcumin_4h_R1 1 HPPDDDLSQDSPEQEASKSPR 21 1 Q9P0K8-2;Q9P0K8 Q9P0K8-2 FOXJ2 Forkhead box protein J2 1 0 HPPDDDLSQDS(0.403)PEQEAS(0.298)KS(0.298)PR 63.894 0.0026311 18906000 2634.7 2270.7 2529.3 2750.3 2385.7 2784.8 1728.5 1254.5 3230 2289.3 TRUE FALSE FALSE 2426.160715 2466.96919 2623.038083 2738.919987 2357.252086 2207.201089 1776.997058 1636.991275 2875.677081 2368.853005 1.024192177 1.04141928 1.107303019 1.156222012 0.995102727 0.931759415 0.750150834 0.691048061 1.213953367 1 11.20997296 -4.826357648 1.987288692 1.031656167 0.688490982 0.769322535 0.075294137 0.102842866 0.759207238 0.008138413 0.042676291 1.49E-05 4.826357648 -0.343165185 HPPDDDLSQDSPEQEAS(ph)KSPR ddPTM_HeLa_Curcumin_4h_R1 1 HPPDDDLSQDSPEQEASKSPR 21 1 Q9P0K8-2;Q9P0K8 Q9P0K8-2 FOXJ2 Forkhead box protein J2 1 0 HPPDDDLS(0.017)QDS(0.001)PEQEAS(0.491)KS(0.491)PR 67.418 0.0016626 11386000 1223.8 1061.9 1161.5 1223 1402.8 1857.3 1039.8 1049.5 1568 1513.5 TRUE FALSE FALSE 1126.934939 1153.685904 1204.546212 1217.93955 1386.072526 1472.075044 1068.97399 1369.487719 1395.994323 1566.094012 0.719583199 0.736664527 0.769140423 0.777692489 0.885050652 0.939965949 0.68257332 0.874460733 0.891386029 1 10.6129551 -9.420713849 1.151223638 0.999900523 0.791450069 0.30817461 0.082671677 0.329548045 0.781758238 0.054520492 0.013775885 3.80E-10 9.420713849 -0.208450454 HPPLYQAGLTPPLS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 2 HPPLYQAGLTPPLSPPK 17 0 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 1 0 HPPLYQAGLTPPLS(1)PPK;HPPLYQAGLTPPLS(1)PPK ; 76.118 0.0060368 170689000 3290.6 2691.06 3389.78 3379.5 3432.7 3856.5 2851.7 1553.71 3540.1 3281.1 TRUE FALSE FALSE 3030.145538 2923.663235 3515.408229 3365.516524 3391.767294 3056.618428 2931.711027 2027.429027 3151.759887 3395.117981 0.892500807 0.861137448 1.035430359 0.99128117 0.999013087 0.900298147 0.86350785 0.59716011 0.928321167 1 11.72924599 -4.100170299 1.547344436 0.953331339 0.347266496 0.809272832 0.05193488 0.592894811 0.964355448 0.008681497 0.610001438 7.94E-05 4.100170299 -0.606064843 HPQGEQMYR ddPTM_HeLa_Curcumin_4h_R1 1 HPQGEQMYR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 106.68 0.0081589 1278000 250 269.65 455.3 397.62 345.6 51.551 125.31 170.72 302.49 310.49 FALSE FALSE TRUE 230.2122362 292.9573445 472.1738185 395.9747538 341.4789457 40.8587415 128.8258613 222.7717421 269.3076038 321.2795044 0.716548155 0.911845731 1.469666792 1.232493042 1.062871864 0.127175064 0.400977528 0.693389211 0.838234622 1 8.327685139 -5.272595734 24.94599889 0.95274048 0.406560288 0.568242104 0.243056721 469.6968197 1050258.514 0.039850689 0.089877549 5.34E-06 5.272595734 -0.546180193 HPS(ph)SPSALR ddPTM_HeLa_Curcumin_4h_R1 2 HPSSPSALR 9 0 O60504-2;O60504;H0YAZ3;H0YB51 O60504-2 SORBS3 Vinexin 1 0 HPS(0.918)S(0.081)PS(0.001)ALR;HPS(0.943)S(0.057)PSALR ; 108.9 0.0044907 48390000 547.37 560.55 484.77 342.45 668.74 856.5 511.79 504.01 679.92 422.11 TRUE FALSE FALSE 504.0450869 609.0014442 502.7360026 341.0330326 660.7657123 678.8522453 526.14945 657.6803288 605.3344771 436.7782911 1.154006729 1.394303372 1.151009592 0.780792085 1.512817202 1.554226158 1.204614471 1.505753244 1.385907884 1 8.770757342 -1.000000001 0.129081644 0.918611027 2.720476043 0.050849497 0.232189662 74.77686404 0.652205082 0.714243098 24.59135496 0.1 1.000000001 1.801865016 HPWDDISYVLPEHMS(ph)M ddPTM_HeLa_Curcumin_4h_R1 1 HPWDDISYVLPEHMSM 16 0 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 1 0 HPWDDISY(0.001)VLPEHMS(0.999)M 53.519 0.0091335 0 1475.9 1436.5 1596.9 1961.6 1914.8 1664.9 1561.5 1655.8 1971.5 2014.5 TRUE FALSE FALSE 1359.080958 1560.664659 1656.082519 1953.483419 1891.967261 1319.580973 1605.311487 2160.645798 1755.231382 2084.503725 0.651992578 0.748698427 0.794473283 0.937145564 0.907634387 0.633043231 0.770116872 1.036527674 0.842038017 1 11.02548823 -9.60703325 1.432237412 0.999167539 0.785611009 0.03289526 0.128634119 0.436950528 1.618770282 0.088066314 0.020641536 2.47E-10 9.60703325 -0.21355653 HQEGEIFDTEK(ac)EK ddPTM_HeLa_Curcumin_4h_R1 2 HQEGEIFDTEKEK 13 1 Q02878 Q02878 RPL6 60S ribosomal protein L6 0 1 ; HQEGEIFDTEK(1)EK;HQEGEIFDTEK(1)EK 150.22 0.00029457 8593300 3817.7 5215.2 3859.5 3502.4 7783.6 8612.4 6984.8 6233.9 7821.6 3355.8 FALSE TRUE FALSE 3515.525017 5665.97865 4002.536465 3487.907997 7690.785654 6826.091158 7180.774689 8134.587413 6963.590049 3472.4138 1.012415345 1.631711822 1.152666904 1.004462082 2.214824067 1.965805791 2.067949013 2.342631921 2.005403287 1 11.76172317 -5.762092042 24.99999987 1.070299484 2.129099215 0.51989865 0.359494629 4.733507917 181327.3224 0.032000088 0.060624699 1.73E-06 5.762092042 1.05879973 HQGVMVGMGQK ddPTM_HeLa_Curcumin_4h_R1 22 HQGVMVGMGQK 11 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;C9JZR7;C9JTX5;Q562R1;P63261;I3L3I0;I3L1U9;K7EM38;I3L3R2;J3KT65;P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P60709;P63261;P68133 ACTB;ACTBL2;ACTG1;ACTA1;ACTC1;ACTG2;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle" 0 0 ;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;; 161.17 2.73E-08 1839888300 167530 116473.38 140906.3 133791.1 143259.1 177607.2 143059.5 137070.7 149683.3 139947.7 FALSE FALSE TRUE 154269.8237 126540.82 146128.4114 133237.5079 141550.8288 140769.4647 147073.3645 178862.9254 133263.4165 144810.8722 1.065319347 0.873835079 1.009098345 0.920079452 0.977487579 0.972091823 1.015623774 1.235148458 0.920258365 1 17.1438104 -4.26307604 5.171729108 1.003507526 1.245207241 0.596562886 0.060198739 0.090011231 8.0316805 0.00842828 0.077134775 5.46E-05 4.26307604 0.241699715 PAETPVATS(ph)PTATDSTSGDSSR ddPTM_HeLa_Curcumin_4h_R1 1 PAETPVATSPTATDSTSGDSSR 22 0 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 0 PAETPVAT(0.011)S(0.775)PT(0.013)AT(0.134)DS(0.01)T(0.015)S(0.02)GDS(0.011)S(0.011)R 127.01 0.00010055 0 760.72 766.59 744.53 692.49 838.6 869.6 749.12 1535.9 806.76 583.01 TRUE FALSE FALSE 700.5082093 832.8506237 772.1229368 689.6246599 828.6002427 689.2351576 770.138291 2004.18884 718.2604464 603.2695541 1.161186081 1.38056134 1.279897073 1.143145142 1.373515764 1.142499489 1.276607258 3.322211151 1.190612789 1 9.236658964 -4.26009764 4.522036303 1.145024133 3.467643288 0.963672733 0.122212432 0.029375389 1.525430527 0.02065543 0.216631234 5.49E-05 4.26009764 2.322619156 up HQPTAIIAK ddPTM_HeLa_Curcumin_4h_R1 1 HQPTAIIAK 9 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 0 0 88.496 0.0071342 7365900 4457.1 3118.8 4741.3 3526.6 4574.7 5612.7 4465.3 3791.3 3948.9 4084.6 FALSE FALSE TRUE 4104.315832 3388.375175 4917.016749 3512.007864 4520.14969 4448.562752 4590.5843 4947.249917 3515.71555 4226.539546 0.971081848 0.801690162 1.163367028 0.830941678 1.069468212 1.05253073 1.086133053 1.170520201 0.831818917 1 12.04526123 -4.709656643 1.000750882 0.976393944 1.19117244 0.312956279 0.107354775 0.938282483 1.129135762 0.013640083 0.181771634 1.95E-05 4.709656643 0.214778497 HQQQLLAS(ph)PGSSTVDNK ddPTM_HeLa_Curcumin_4h_R1 2 HQQQLLASPGSSTVDNK 17 0 F2Z2X4;Q9C0E2 F2Z2X4 XPO4 Exportin-4 1 0 HQQQLLAS(1)PGSSTVDNK;HQQQLLAS(0.997)PGS(0.003)STVDNK ; 245.04 1.12E-30 46808300 8079.7 7090.5 7561.2 7756 7148 8548.8 6487.5 4447.8 8213.1 7659.8 TRUE FALSE FALSE 7440.183219 7703.371225 7841.424724 7723.907727 7062.764769 6775.682515 6669.52179 5803.913745 7312.143478 7925.97748 0.938708599 0.971914347 0.989332198 0.974505384 0.891090693 0.854870271 0.841476248 0.732264728 0.922554158 1 12.95237315 -4.006102393 0.552898793 0.975883367 0.509796118 0.869047503 0.028728286 1.137039219 0.193003967 0.005617498 0.361595682 9.86E-05 4.006102393 -0.466087249 HRATGEGGAS(ph)DLPEDPDEDAIPIT ddPTM_HeLa_Curcumin_4h_R1 1 HRATGEGGASDLPEDPDEDAIPIT 24 1 O15541 O15541 RNF113A RING finger protein 113A 1 0 HRAT(0.206)GEGGAS(0.794)DLPEDPDEDAIPIT 77.907 0.00014387 10872000 1861.8 1348.8 1717.6 1657.8 1736.5 2400.7 1315.4 1462.9 2427.5 1724.5 TRUE FALSE FALSE 1714.436565 1465.384262 1781.255767 1650.940463 1715.793372 1902.767759 1352.306584 1908.931476 2161.209323 1784.426247 0.960777487 0.821207525 0.99822325 0.925194003 0.961537847 1.066319083 0.757838317 1.069773256 1.211150826 1 10.80124456 -8.198542155 1.471659878 0.990948578 0.941450522 0.09992269 0.115370325 0.816173613 3.583427026 0.020705558 0.016316359 6.33E-09 8.198542155 -0.049498056 HRDLLHNEDR ddPTM_HeLa_Curcumin_4h_R1 1 HRDLLHNEDR 10 1 Q8N684-2;Q8N684;Q8N684-3;F5H669 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 0 0 72.434 0.019018 712390 229.54 64.699 131.9 217 174.05 186.34 169.79 249.2 314.72 283.94 FALSE FALSE TRUE 211.3716668 70.29129327 136.78833 216.1021115 171.9745674 147.6909835 174.5538504 325.1799328 280.1960034 293.8068939 0.719423782 0.239243172 0.465572227 0.735524305 0.585331968 0.502680456 0.594110806 1.106781153 0.953674026 1 8.198724437 -8.337464795 1.090803481 0.953262847 0.602936587 0.30781624 0.212285356 0.37752865 0.923985987 0.065050962 0.043594262 4.60E-09 8.337464795 -0.350326261 HRDYETATLSDIK ddPTM_HeLa_Curcumin_4h_R1 2 HRDYETATLSDIK 13 1 O43707;O43707-2 O43707 ACTN4 Alpha-actinin-4 0 0 ; ; 115.33 0.0013567 25745000 8558.7 5516.7 7448.4 6844 8559.8 11232.7 8407.2 7945 7352.5 6904.5 FALSE FALSE TRUE 7881.269864 5993.538966 7724.444256 6815.681341 8457.729976 8902.911401 8643.083405 10367.39393 6545.949145 7144.430861 1.103134738 0.838910626 1.081183989 0.953985205 1.183821376 1.246133047 1.209765141 1.451115439 0.916231016 1 12.80260337 -4.630322386 0.803726388 1.029456927 1.517364289 0.697425762 0.094846296 0.714132031 0.458825525 0.014715712 0.275675116 2.34E-05 4.630322386 0.487907362 HREDS(ph)DVEMVEDDSRK ddPTM_HeLa_Curcumin_4h_R1 2 HREDSDVEMVEDDSRK 16 2 H0Y4N0;H0Y806;E7EUC9;A0A087WX20;A0A669KB03;A0A669KBB4;A0A669KBK2;H0Y818;A0A669KAW3;P40692-2;P40692-3;P40692 H0Y4N0 MLH1 DNA mismatch repair protein Mlh1 1 0 HREDS(1)DVEMVEDDSRK;HREDS(1)DVEMVEDDSRK ; 75.743 0.0050343 40986000 4221 3443.4 3622.7 4163.8 4214.9 4417.9 3451.8 3709.3 3708 3946.8 TRUE FALSE FALSE 3886.903396 3741.032153 3756.960449 4146.571299 4164.64007 3501.57774 3548.648218 4840.248494 3301.241677 4083.951006 0.951750741 0.916032574 0.919932791 1.015333262 1.019757598 0.857399546 0.868925267 1.185187699 0.808345074 1 11.99574984 -9.261438277 1.101938496 0.999002422 0.959857642 0 0.107508702 1.769938095 3.990712358 0.050204278 0.015141587 5.48E-10 9.261438277 -0.039144781 HRGS(ph)ADYSMEAK ddPTM_HeLa_Curcumin_4h_R1 1 HRGSADYSMEAK 12 1 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 0 HRGS(1)ADYSMEAK 99.055 0.0042963 11425000 9293.9 8200.2 7779.8 7974.6 9127.1 12192 9178.8 5399.3 11100 7772.1 TRUE FALSE FALSE 8558.278008 8908.988749 8068.126232 7941.603218 9018.265294 9663.241768 9436.332425 7045.521715 9882.357771 8042.179896 1.064173908 1.107782823 1.003226281 0.987493854 1.121370749 1.201569959 1.173355054 0.876071141 1.228815806 1 12.97337089 -5.746250949 24.80619896 1.032534338 1.106573282 0 0.107689502 339.1765111 553949.6353 0.012451693 0.024823059 1.79E-06 5.746250949 0.074038943 HRHS(ph)PTGPPGFPR ddPTM_HeLa_Curcumin_4h_R1 2 HRHSPTGPPGFPR 13 1 P98175-5;P98175-2;P98175 P98175-5 RBM10 RNA-binding protein 10 1 0 HRHS(1)PTGPPGFPR;HRHS(1)PTGPPGFPR ; 76.156 0.010154 24561000 6677.6 5541.7 4826.5 5747.9 6642.4 7521.4 5330.4 4772.4 6689.1 5871.8 TRUE FALSE FALSE 6149.060914 6020.699855 5005.374336 5724.116713 6563.193718 5961.376856 5479.956678 6227.482791 5955.322465 6075.844613 1.012050391 0.990923935 0.823815396 0.942110452 1.080210923 0.98116019 0.901925086 1.024957547 0.980163721 1 12.56886926 -6.985604451 24.99738591 1.005469252 0.957611881 0.067927621 0.064866704 417.0761061 724236.612 0.010464238 0.013749105 1.03E-07 6.985604451 -0.04785737 EGVK(ac)TENNDHINLK ddPTM_HeLa_Curcumin_4h_R1 1 EGVKTENNDHINLK 14 1 P61956-2;P61956 P61956-2 SUMO2 Small ubiquitin-related modifier 2 0 1 EGVK(1)TENNDHINLK 158.93 0.00066762 16743000 2827.7 2538.9 2855.1 3048.7 2743.7 4828.3 6516.1 9193.8 2878.6 2504.7 FALSE TRUE FALSE 2603.884561 2758.351203 2960.912518 3036.085287 2710.983169 3826.856154 6698.924229 11996.9473 2562.824782 2591.738139 1.004686593 1.064286226 1.142442778 1.171447548 1.046009676 1.476559725 2.584722634 4.628919534 0.988844029 1 11.33970424 -4.213194996 1.269180415 1.023876569 6.56410724 0.996460988 0.065797012 0.064876442 0.081133839 0.010677245 0.480053623 6.12E-05 4.213194996 5.540230672 up HRPDLIDFDK ddPTM_HeLa_Curcumin_4h_R1 2 HRPDLIDFDK 10 1 A0A087WUZ3;Q01082;Q01082-2;F8W6C1;P11277-3;P11277;P11277-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1;SPTB "Spectrin beta chain, non-erythrocytic 1;Spectrin beta chain, erythrocytic" 0 0 ; ; 83.862 0.012501 28545000 9764.4 7761.9 8859.9 8685.7 8817.8 10946.9 8961.6 7585.6 9350.6 9166.1 FALSE FALSE TRUE 8991.537437 8432.80405 9188.255688 8649.760875 8712.653494 8676.389543 9213.038377 9898.41452 8324.862574 9484.621293 0.948012278 0.889102874 0.968753038 0.911977464 0.918608474 0.914785027 0.971365972 1.043627807 0.87772219 1 13.21137445 -8.84701293 0.924175026 0.997063029 0.943319697 0 0.055552118 0.644008845 1.076163494 0.020046896 0.008217618 1.42E-09 8.84701293 -0.053743332 HRPS(ph)AGGPDSAGR ddPTM_HeLa_Curcumin_4h_R1 1 HRPSAGGPDSAGR 13 1 Q01970-2;Q01970 Q01970-2 PLCB3 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3" 1 0 HRPS(1)AGGPDSAGR 63.374 0.020145 4269100 356.35 209.39 197.13 305.55 419.59 548.1 263.91 196.17 275.3 317.85 TRUE FALSE FALSE 328.1445215 227.4887386 204.4358112 304.2857151 414.5866633 434.4178816 271.3146043 255.9813299 245.1002788 328.8952638 0.997717382 0.691675325 0.621583324 0.92517512 1.260543124 1.320839578 0.824927064 0.778306525 0.745222889 1 8.361484423 HRPS(ph)PPATPPPK ddPTM_HeLa_Curcumin_4h_R1 1 HRPSPPATPPPK 12 1 A9Z1X7;Q8IYB3;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 HRPS(1)PPATPPPK 82.925 0.0095668 18372000 4043 3326.8 3530.2 4033.1 4366.9 4449.4 3135.8 7186.1 5300.9 4179.1 TRUE FALSE FALSE 3722.992284 3614.353768 3661.032317 4016.412101 4314.82757 3526.544285 3223.782108 9377.108809 4719.404532 4324.323414 0.860942147 0.835819485 0.846613902 0.928795494 0.997804086 0.815513538 0.74549977 2.168456869 1.091362528 1 12.07825871 -4.256960566 24.99996802 0.907194061 2.168457372 0.937187025 0.098316705 72.25740502 403313.8106 0.012556453 0.13378805 5.53E-05 4.256960566 1.261263311 HRPSAGGPDS(ph)AGR ddPTM_HeLa_Curcumin_4h_R1 2 HRPSAGGPDSAGR 13 1 Q01970-2;Q01970 Q01970-2 PLCB3 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3" 1 0 HRPSAGGPDS(1)AGR;HRPSAGGPDS(1)AGR ; 72.428 0.014087 2970500 611.88 455.4 340.77 404.4 590.75 877.28 577.97 312.401 539.94 391.95 TRUE FALSE FALSE 563.4490523 494.7627468 353.399236 402.7267 583.7056921 695.322239 594.1862827 407.6506268 480.7099329 405.5702333 1.38927615 1.219918786 0.87136384 0.992988802 1.439222221 1.714431144 1.465063838 1.005129552 1.185269266 1 8.66380796 -9.481717054 1.132302815 0.994564313 1.279233126 0.047007631 0.248772533 0.870794948 1.934984268 0.201520498 0.045586393 3.30E-10 9.481717054 0.284668813 HRS(ph)NSFSDER ddPTM_HeLa_Curcumin_4h_R1 1 HRSNSFSDER 10 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 HRS(0.999)NS(0.001)FSDER 89.356 0.0088947 11446000 4042.2 2842.8 3410.6 3030 3351.2 6114.5 2968.9 3112.7 4462.5 2879.1 TRUE FALSE FALSE 3722.255605 3088.518965 3536.999836 3017.462663 3311.239129 4846.283775 3052.199344 4061.747901 3972.974915 2979.148511 1.249436069 1.036711985 1.187251936 1.012860773 1.111471656 1.626734538 1.024520709 1.36339222 1.333594113 1 11.54068433 -13.52287875 0.156107344 0.264054188 1.275174365 0 0.1992527 88.77564448 0.932629632 20.39957479 0.35543923 3.00E-14 13.52287875 1.011120177 HRSNS(ph)FSDER ddPTM_HeLa_Curcumin_4h_R1 1 HRSNSFSDER 10 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 HRS(0.099)NS(0.895)FS(0.006)DER 69.846 0.019411 19008000 2610.4 2079 2312.4 2054.7 2670.6 4258.7 1987.6 2270.9 2893 1993.6 TRUE FALSE FALSE 2403.784086 2258.699496 2398.099578 2046.198196 2638.754839 3375.397615 2043.366707 2963.286956 2575.645138 2062.877452 1.165257822 1.094926649 1.162502201 0.991914568 1.27916219 1.636256973 0.990541976 1.436482305 1.248569146 1 11.0104424 -1.000000002 0.104863592 0.899887012 2.231085934 0.123991378 0.186179964 113.5885997 0.842307839 1.166508006 21.90364563 0.099999999 1.000000002 1.331198922 HS(ph)ASPVVFTSAR ddPTM_HeLa_Curcumin_4h_R1 1 HSASPVVFTSAR 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 HS(0.614)AS(0.373)PVVFT(0.013)SAR 127.52 0.002791 9649800 1190.2 830.76 1376.1 1236.2 1017.3 1598 856.38 865.93 1305.9 1195.7 TRUE FALSE FALSE 1095.994414 902.5671926 1427.099477 1231.084932 1005.169362 1266.556787 880.407718 1129.948071 1162.646037 1237.250486 0.88583066 0.729494312 1.153444264 0.995016729 0.812421877 1.023686635 0.711584055 0.913273491 0.939701419 1 10.27292189 -13.52287875 0.271645791 1.721476463 0.892990247 0.027020567 0.128630093 96.49310497 1.296819917 37.6329168 0.062652917 3.00E-14 13.52287875 -0.828486216 HS(ph)FNSFR ddPTM_HeLa_Curcumin_4h_R1 1 HSFNSFR 7 0 P51828 P51828 ADCY7 Adenylate cyclase type 7 1 0 HS(0.999)FNS(0.001)FR 103.83 0.017736 14606000 329.89 1310.8 241.3 198.04 302.51 270.58 228.78 215.16 370.17 314.07 TRUE FALSE FALSE 303.7788584 1424.099711 250.2427903 197.220563 298.9027658 214.4586579 235.1989511 280.7612935 329.5632771 324.9839091 0.93475046 4.382062223 0.77001594 0.606862547 0.919746355 0.659905466 0.723724912 0.863923676 1.014091061 1 8.344224478 HS(ph)LEEGLDMVNR ddPTM_HeLa_Curcumin_4h_R1 2 HSLEEGLDMVNR 12 0 Q7Z309;Q7Z309-2;Q7Z309-5 Q7Z309 FAM122B Protein FAM122B 1 0 HS(1)LEEGLDMVNR;HS(1)LEEGLDMVNR ; 146.59 0.00036766 26214000 7184.8 6019.2 6018.8 5912.2 5971.4 7361.6 6412.9 8481.8 6829.1 5776 TRUE FALSE FALSE 6616.115499 6539.472827 6241.862023 5887.736883 5900.194955 5834.721178 6592.828715 11067.86177 6079.964816 5976.71557 1.106981823 1.09415828 1.044363238 0.985112444 0.987196879 0.97624207 1.103085572 1.851830097 1.017275248 1 12.54513717 -4.262841722 4.377958088 1.040871739 1.908996943 0.968425172 0.044379025 0.030126247 1.38734754 0.007689453 0.080727179 5.46E-05 4.262841722 0.868125204 HS(ph)PIAPSSPS(ph)PQVLAQK ddPTM_HeLa_Curcumin_4h_R1 1 HSPIAPSSPSPQVLAQK 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 2 0 HS(0.999)PIAPS(0.123)S(0.383)PS(0.496)PQVLAQK 100.53 0.0044638 7562900 4336.4 3731.9 4582.2 3343.8 4465.9 4319.3 3895.5 1477.6 4134.6 4050.9 TRUE FALSE FALSE 3993.169364 4054.468807 4752.020363 3329.964242 4412.647059 3423.428491 4004.797246 1928.113438 3681.044724 4191.668473 0.952644368 0.967268483 1.133682302 0.794424526 1.052718527 0.816722151 0.955418414 0.459987103 0.878181265 1 12.0333089 -4.018050122 1.845735218 0.972815311 1.46E-16 0.672772677 0.100791486 0.701025127 1.38494422 0.012082768 1.454476975 9.59E-05 4.018050122 -0.972815311 HS(ph)PPMVR ddPTM_HeLa_Curcumin_4h_R1 1 HSPPMVR 7 0 C9K0K7;I3L0S1;E7EPA1;O60256-4;O60256-3;O60256-2;O60256;I3L4G9 C9K0K7 PRPSAP2 Phosphoribosyl pyrophosphate synthase-associated protein 2 1 0 HS(1)PPMVR 78.149 0.016598 9628300 1337.6 1194.5 1226.8 992.35 1468.6 1513.8 1006.7 716.92 1266.2 945.42 TRUE FALSE FALSE 1231.727549 1297.747257 1272.266287 988.2439186 1451.087904 1199.820816 1034.945293 935.5056077 1127.301028 978.2732746 1.259083306 1.326569263 1.30052238 1.010192085 1.483315493 1.226467948 1.057930662 0.956282495 1.152337549 1 9.934093719 -9.307324442 1.062284659 1.001469579 1.211133066 0.06147769 0.157197596 0.645009479 1.317189263 0.09902416 0.027160987 4.93E-10 9.307324442 0.209663487 HS(ph)PVS(ph)PS(ph)TKT(ph)ER ddPTM_HeLa_Curcumin_4h_R1 1 HSPVSPSTKTER 12 1 A0A5F9ZI30;A0A5F9ZGY4;A0A5F9ZHS1;A0A5F9ZGX3;A0A5F9ZHE4;D6RHE1;A0A5F9ZHR8;A0A5F9ZHD2;A0A5F9ZGY3;I6L894;A0A5F9ZI40;A0A5F9ZHN5;A0A5F9ZH19;A0A5F9ZHT8;A0A5F9ZI46;A0A5F9ZI65;A0A5F9ZGZ5;A0A5F9ZHT4;A0A5F9ZHF7;A0A5F9ZH30;Q01484 A0A5F9ZI30 ANK2 Ankyrin-2 4 0 HS(1)PVS(0.994)PS(0.561)T(0.561)KT(0.884)ER 57.414 0.020252 64792000 4475.9 4283.1 3912.8 4440.3 4246 5320.4 3357.5 2814.2 4984.2 4425.6 TRUE FALSE FALSE 4121.627792 4653.312079 4057.81181 4421.927215 4195.369223 4216.889067 3451.702414 3672.236625 4437.44573 4579.389271 0.900038749 1.016142504 0.886103271 0.965615053 0.916141646 0.920840928 0.753747325 0.801905321 0.969003827 1 12.16093949 -4.839860306 4.555206175 0.949307011 0.777537483 0.734238469 0.040846138 0.082476713 3.119931377 0.006481546 0.021343985 1.45E-05 4.839860306 -0.171769528 HS(ph)S(ph)ISPVRLPLNSSLGAELSR ddPTM_HeLa_Curcumin_4h_R1 2 HSSISPVRLPLNSSLGAELSR 21 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 2 0 HS(0.697)S(0.651)IS(0.651)PVRLPLNSSLGAELSR;HS(0.663)S(0.663)IS(0.664)PVRLPLNS(0.007)S(0.003)LGAELSR ; 72.145 0.0010847 22909600 1900.21 1529.93 1588.56 1819.64 1583.03 2332.5 1648.98 1525.06 1922.94 1762.19 TRUE FALSE FALSE 1749.806373 1662.170332 1647.433431 1812.110812 1564.153401 1848.713207 1695.245941 1990.043773 1711.998293 1823.425971 0.959625672 0.911564472 0.903482487 0.993794561 0.857810202 1.013867981 0.929703738 1.091376236 0.938891033 1 10.83243591 -2.999950042 22.21818085 0.968566946 0.961744794 0 0.064017228 0 0 0.007809964 0 0.001000115 2.999950042 -0.006822152 HS(ph)SPAPAQPK ddPTM_HeLa_Curcumin_4h_R1 1 HSSPAPAQPK 10 0 I3L4X5;Q70CQ4 I3L4X5 USP31 Ubiquitin carboxyl-terminal hydrolase 31 1 0 HS(0.5)S(0.5)PAPAQPK 83.182 0.013183 1962600 1722.8 2533 1470.5 1293.8 913.5 1474.7 749.69 439.83 1149.1 1760.7 TRUE FALSE FALSE 1586.438562 2751.941233 1524.998024 1288.446598 902.6071091 1168.830597 770.7242837 573.9321423 1023.046605 1821.884194 0.870768058 1.510491854 0.837044434 0.707205542 0.495425073 0.641550435 0.423036923 0.315021198 0.561532181 1 10.83121554 -6.057294296 2.081489174 0.98389256 0.472286238 0.496700187 0.232186232 0.169901976 1.455912679 0.030565336 0.057975939 8.76E-07 6.057294296 -0.511606322 HS(ph)SPSGTVAAR ddPTM_HeLa_Curcumin_4h_R1 1 HSSPSGTVAAR 11 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 HS(0.5)S(0.5)PSGTVAAR 69.229 0.019394 4312900 1157 831.82 828.19 889.01 1121.5 1033.4 693.4 529.44 1203.1 1037.5 TRUE FALSE FALSE 1065.422229 903.7188143 858.88345 885.3315122 1108.126845 819.0611912 712.8549378 690.8638188 1071.12294 1073.553048 0.992426254 0.841801731 0.800038202 0.824674211 1.03220502 0.762944312 0.664014637 0.64353021 0.997736388 1 10.06817777 -3.115925639 0.269066556 1.014801053 2.61E-14 0.63900666 0.081823152 7.341197058 0.248008292 0.045146035 2.757741696 0.000765728 3.115925639 -1.014801053 VKEEPPS(ph)PPQSPR ddPTM_HeLa_Curcumin_4h_R1 1 VKEEPPSPPQSPR 13 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 0 VKEEPPS(0.99)PPQS(0.01)PR 66.826 0.017607 47757000 3411.1 2802.5 2936.7 3189.1 2797.6 3639 1930.4 1017.1 3009.4 2929.8 TRUE FALSE FALSE 3141.107836 3044.735612 3045.536685 3175.904349 2764.240447 2884.23038 1984.561829 1327.209108 2679.276349 3031.610332 1.036118594 1.004329475 1.004593715 1.047596492 0.911805986 0.951385589 0.654622993 0.437790139 0.883779924 1 11.56586861 -4.470042876 1.282042377 1.015167408 0.288842745 0.915445574 0.054288869 0.106346024 0.193213079 0.004791496 0.091109208 3.39E-05 4.470042876 -0.726324663 down HSAGS(ph)GAEESNSSSTVQK ddPTM_HeLa_Curcumin_4h_R1 2 HSAGSGAEESNSSSTVQK 18 0 Q8IYL3 Q8IYL3 C1orf174 UPF0688 protein C1orf174 1 0 HS(0.033)AGS(0.967)GAEESNSSSTVQK;HS(0.266)AGS(0.734)GAEESNSSSTVQK ; 153.76 2.83E-05 30359000 11326.8 9828.1 8704.4 8674.5 12338 16248.2 11223.1 6006.6 12526.9 9929.1 TRUE FALSE FALSE 10430.27183 10677.59717 9026.992721 8638.607217 12190.87741 12878.14017 11537.98998 7837.984689 11152.73041 10274.13549 1.01519703 1.039269648 0.878613362 0.840811106 1.186559923 1.253452437 1.123013221 0.762885082 1.085515217 1 13.32672938 -5.740431191 24.99888308 0.988906461 1.096728353 0.113687161 0.138403475 399.0760168 474881.8 0.01944983 0.038866943 1.82E-06 5.740431191 0.107821892 HSAIS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 HSAISPK 7 0 A0A0C4DGZ1;Q8N5P1 A0A0C4DGZ1 ZC3H8 Zinc finger CCCH domain-containing protein 8 1 0 HSAIS(1)PK 83.998 0.014421 4750900 4903.6 10773 3344.1 4043.7 2080.3 3370.3 2782 1628 2565.2 3091.9 TRUE FALSE FALSE 4515.474886 11704.17012 3468.035288 4026.968241 2055.493781 2671.261789 2860.055433 2124.369706 2283.803978 3199.343295 1.411375545 3.65830392 1.083983483 1.258685883 0.642473655 0.834940656 0.89395078 0.6640018 0.713835237 1 11.64356009 -5.923074149 3.133611807 1.410491571 0.774166954 0.184747464 0.766341676 0.424802865 8.438541269 0.118608863 0.224973291 1.19E-06 5.923074149 -0.636324617 LDTGS(ph)PEPETR ddPTM_HeLa_Curcumin_4h_R1 2 LDTGSPEPETR 11 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 0 LDT(0.235)GS(0.764)PEPET(0.001)R;LDT(0.03)GS(0.97)PEPETR ; 158.01 0.00038754 265950000 13448.7 10295.9 12579.5 12123.5 12810.9 12268.8 6733.5 1749.91 12888.1 11545.2 TRUE FALSE FALSE 12384.2212 11185.83172 13045.70734 12073.33617 12658.13838 9724.112582 6922.423888 2283.449503 11474.30767 11946.39484 1.036649246 0.936335344 1.092020439 1.010625911 1.059578103 0.813978837 0.579457148 0.191141305 0.960482876 1 13.54428769 -4.469076651 1.322106515 1.020404195 0.012814633 0.964662857 0.050111573 0.099807905 0.196190144 0.006544202 0.121229593 3.40E-05 4.469076651 -1.007589562 down HSCSGS(ph)SPPR ddPTM_HeLa_Curcumin_4h_R1 2 HSCSGSSPPR 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 HSCSGS(0.5)S(0.5)PPR;HSCSGS(0.607)S(0.393)PPR ; 136.27 0.00096016 18236600 0 63.561 0 110.36 0 0 0 0 0 0 TRUE FALSE FALSE 0 69.05492962 0 109.9033596 0 0 0 0 0 0 0 HSCSPMGDGDPEAMEES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 HSCSPMGDGDPEAMEESPR 19 0 Q9P275;A0A075B784 Q9P275 USP36 Ubiquitin carboxyl-terminal hydrolase 36;Ubiquitin carboxyl-terminal hydrolase 1 0 HSCSPMGDGDPEAMEES(1)PR;HSCSPMGDGDPEAMEES(1)PR ; 109.68 0.00023909 23448000 2320.7 2281.53 2504.35 2493.94 2451.06 3422.9 2416.58 1666.27 2846.18 2463.62 TRUE FALSE FALSE 2137.014146 2478.735287 2597.163414 2483.620737 2421.83271 2712.951956 2484.382731 2174.308052 2533.961175 2549.230612 0.838297695 0.972346431 1.018802851 0.974262872 0.95002496 1.064223826 0.974561783 0.85292717 0.994010178 1 11.31584617 -7.039593037 24.97269431 0.922676443 0.977443087 0.003686727 0.066108333 921.0121982 580912.4533 0.012700836 0.015556594 9.13E-08 7.039593037 0.054766644 HSDSGTSEASLS(ph)PPSS(ph)PPSRPR ddPTM_HeLa_Curcumin_4h_R1 2 HSDSGTSEASLSPPSSPPSRPR 22 1 A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4 A0A1B0GV47 KIF21A Kinesin-like protein KIF21A 2 0 HSDSGTSEAS(0.153)LS(0.844)PPS(0.025)S(0.974)PPS(0.003)RPR;HSDSGTSEAS(0.075)LS(0.919)PPS(0.152)S(0.495)PPS(0.358)RPR ; 93.229 0.00028163 0 2842.4 3197.9 2732.6 2527.1 3404.1 3976.3 2727.48 2185.3 3384.2 2754.3 TRUE FALSE FALSE 2617.421041 3474.312226 2833.87256 2516.64353 3363.508331 3151.570558 2804.005748 2851.58791 3012.961727 2850.01172 0.918389571 1.219051908 0.99433716 0.883029186 1.180173508 1.105809683 0.98385762 1.000553047 1.057175206 1 11.47675214 HSEAATAQREEWK ddPTM_HeLa_Curcumin_4h_R1 1 HSEAATAQREEWK 13 1 Q14103-3;D6RAF8;Q14103;D6RD83;H0Y8G5 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 0 109.16 0.0036468 3898800 5288.4 4242.6 4580.2 4576.6 4748 5607.2 4808.7 4135.2 5825.6 4852.2 FALSE FALSE TRUE 4869.81756 4609.311439 4749.946241 4557.663242 4691.383201 4444.203514 4943.61918 5396.003444 5186.546255 5020.813589 0.969925984 0.918040743 0.946051104 0.907753925 0.934387051 0.885156048 0.98462512 1.074726904 1.033009126 1 12.29370545 -7.926643694 1.345119657 0.992210169 0.947047371 0.168868162 0.051127911 0.570647544 2.150443518 0.011818404 0.010401767 1.18E-08 7.926643694 -0.045162798 HSGNITFDEIVNIAR ddPTM_HeLa_Curcumin_4h_R1 4 HSGNITFDEIVNIAR 15 0 P30050;P30050-2 P30050 RPL12 60S ribosomal protein L12 0 0 ;;; ;;; 141.06 0.00042299 39899300 2626.43 2448.04 3173.37 3122.4 2419.71 3723.7 2594.09 2478.04 2467.61 2193.23 FALSE FALSE TRUE 2418.545294 2659.637669 3290.977884 3109.480336 2390.856539 2951.362645 2666.873184 3233.582989 2196.919357 2269.444579 1.065699209 1.171933298 1.450124808 1.370150373 1.053498535 1.300477955 1.175121529 1.424834525 0.968042743 1 11.14812354 -7.147405228 3.073500892 1.029657461 1.283968562 0.552737634 0.113264352 0.151779359 2.730334031 0.018896131 0.023338446 7.12E-08 7.147405228 0.254311101 HSGPNSADSANDGFVR ddPTM_HeLa_Curcumin_4h_R1 2 HSGPNSADSANDGFVR 16 0 P52597 P52597 HNRNPF "Heterogeneous nuclear ribonucleoprotein F;Heterogeneous nuclear ribonucleoprotein F, N-terminally processed" 0 0 ; ; 125.33 0.00023612 3931200 1208.22 971.72 926.68 1031.4 1495.04 2646.4 1386.19 1073.62 1706.7 1163.71 FALSE FALSE TRUE 1112.588112 1055.711147 961.023576 1027.13234 1477.212624 2097.506809 1425.082761 1400.961796 1519.47928 1204.148836 0.923962287 0.876728122 0.79809368 0.852994505 1.226769134 1.74189996 1.183477256 1.163445709 1.26186999 1 10.23379801 -5.617149172 5.079417194 0.936084029 1.365794016 0.495124541 0.189092658 0.10438899 4.440190008 0.023244147 0.047339157 2.41E-06 5.617149172 0.429709987 HSHGPLQADVFVELLS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 HSHGPLQADVFVELLSPR 18 0 Q9NRL2;Q9NRL2-2 Q9NRL2 BAZ1A Bromodomain adjacent to zinc finger domain protein 1A 1 0 HSHGPLQADVFVELLS(1)PR 91.565 0.0012538 0 553.97 402.85 549.1 482.4 620.58 585.16 664.91 468.27 676.35 608.14 TRUE FALSE FALSE 510.12269 437.6705589 569.450129 480.4039566 613.1799888 463.7912199 683.5655851 611.0433674 602.1560971 629.2728197 0.810654257 0.695517978 0.904933617 0.763427152 0.974426305 0.737027256 1.08627858 0.971030924 0.956907844 1 9.29754182 -4.7399026 24.99978146 0.877787098 1.028654779 0.288579845 0.104179473 279.2223587 324114.7173 0.015645257 0.058431117 1.82E-05 4.7399026 0.150867681 HSLDS(ph)DEEEDDDDGGSSK ddPTM_HeLa_Curcumin_4h_R1 4 HSLDSDEEEDDDDGGSSK 18 0 O95400 O95400 CD2BP2 CD2 antigen cytoplasmic tail-binding protein 2 1 0 HS(0.002)LDS(0.998)DEEEDDDDGGSSK;HSLDS(1)DEEEDDDDGGSSK;HSLDS(1)DEEEDDDDGGSSK;HS(0.002)LDS(0.998)DEEEDDDDGGSSK ;;; 230.29 2.65E-57 27114500 8000.26 8086.01 7149.52 8120.55 9909.5 9279.74 8615.38 8981.77 7502.49 7275.83 TRUE FALSE FALSE 7367.030979 8784.928674 7414.487501 8086.949316 9791.335685 7355.01732 8857.104376 11720.27033 6679.485617 7528.664551 0.978530911 1.166864138 0.984834355 1.074154554 1.300540835 0.976935188 1.176450925 1.556752894 0.887207229 1 12.87817826 -1 0.651870023 1.012737646 46.88246259 0.646388353 0.112391064 87.84954473 0.522184367 0.017674084 5829.685824 0.1 1 45.86972495 HSLDS(ph)DEEEDDDDGGSSKYDILASEDVEGQEAATLPSEGGVR ddPTM_HeLa_Curcumin_4h_R1 1 HSLDSDEEEDDDDGGSSKYDILASEDVEGQEAATLPSEGGVR 42 1 O95400 O95400 CD2BP2 CD2 antigen cytoplasmic tail-binding protein 2 1 0 HS(0.051)LDS(0.887)DEEEDDDDGGS(0.016)S(0.016)KY(0.015)DILAS(0.016)EDVEGQEAATLPSEGGVR 48.13 0.002096 237990000 379.28 170.36 186.24 367.88 216.88 326.64 259 264.39 403.31 359.19 TRUE FALSE FALSE 349.2595878 185.0851593 193.1422182 366.35781 214.2938476 258.891182 266.2668429 345.0012939 359.067902 371.6718258 0.939698851 0.497980063 0.519657948 0.985702398 0.576567372 0.696558534 0.716403086 0.928241718 0.966088568 1 8.53788552 -7.418547672 7.925256641 0.973551987 0.70237514 0.400405968 0.149439455 0.202935394 13.85622344 0.024914625 0.02840779 3.81E-08 7.418547672 -0.271176848 HSLEEDEGSDFITENR ddPTM_HeLa_Curcumin_4h_R1 2 HSLEEDEGSDFITENR 16 0 Q9NUQ3 Q9NUQ3 TXLNG Gamma-taxilin 0 0 ; ; 233.62 3.03E-22 10897200 4005.9 3529.7 3236.2 3433.2 3578.1 4757 3346.1 3461.9 3745.5 3496 FALSE FALSE TRUE 3688.828788 3834.79154 3356.136419 3418.994328 3535.433494 3770.344578 3439.98256 4517.417373 3334.628021 3617.48574 1.019721722 1.060070949 0.927753877 0.945130009 0.97731788 1.042255547 0.950931892 1.248772683 0.921808201 1 11.82077161 -4.254426179 24.93817875 1.000298328 1.248772802 0.724682782 0.048106781 288.563225 1026072.919 0.005669036 0.075728342 5.57E-05 4.254426179 0.248474474 FGEYNSNMS(ph)PEEK ddPTM_HeLa_Curcumin_4h_R1 1 FGEYNSNMSPEEK 13 0 E9PFK5;P78316-2;P78316 E9PFK5 NOP14 Nucleolar protein 14 1 0 FGEYNS(0.091)NMS(0.909)PEEK 123.72 0.0021637 40582000 2880.1 2320.9 2773.7 2923.4 2822.3 3165.8 1865.9 883.74 2548.5 2459.4 TRUE FALSE FALSE 2652.137046 2521.508254 2876.495762 2911.303745 2788.645916 2509.177394 1918.252132 1153.188258 2268.935926 2544.863967 1.042152775 0.990822412 1.130314154 1.143991892 1.095793705 0.985977021 0.753773937 0.453143379 0.891574542 1 11.31337283 -4.467442402 1.892519478 1.04097096 0.391519962 0.875070359 0.070169629 0.112272288 0.56209097 0.008747475 0.110181461 3.41E-05 4.467442402 -0.649450998 down HSLSGSS(ph)PGMK ddPTM_HeLa_Curcumin_4h_R1 2 HSLSGSSPGMK 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 HSLS(0.006)GS(0.302)S(0.692)PGMK;HSLSGS(0.249)S(0.751)PGMK ; 118.23 0.0051649 84166000 16142.3 13918.3 12349 12653.2 19069.1 21846.4 15122.1 11079 15041.5 11216.5 TRUE FALSE FALSE 14864.61992 15121.33583 12806.6648 12600.84441 18841.71344 17315.21038 15546.38543 14456.9361 13391.48508 11606.27254 1.280740209 1.302858931 1.103426165 1.085692617 1.623407806 1.491883834 1.339481334 1.245614046 1.15381446 1 13.50261709 -5.780728203 24.99999118 1.144490438 1.423751921 0.533723312 0.12373022 166.5366095 215845.6075 0.022396849 0.040641317 1.66E-06 5.780728203 0.279261483 HSNVVILTTSNITEK ddPTM_HeLa_Curcumin_4h_R1 1 HSNVVILTTSNITEK 15 0 Q15645 Q15645 TRIP13 Pachytene checkpoint protein 2 homolog 0 0 89.507 0.0069326 0 4643.5 4790.9 3891.7 4983.4 4238.6 1378 1875.9 2439.8 5159.6 4887.3 FALSE FALSE TRUE 4275.962075 5205.004048 4035.929825 4962.780011 4188.057463 1092.187267 1928.532705 3183.683789 4593.604789 5057.133311 0.84553082 1.029240031 0.798066726 0.981342533 0.828148519 0.215969641 0.381348995 0.62954318 0.908341645 1 12.30410409 -5.390712264 5.281014572 0.925611133 0.409191542 0.80484902 0.114417331 0.069495878 2.697312546 0.016403237 0.037288492 4.07E-06 5.390712264 -0.516419591 HSPEEDFRQS(ph)PQEHFR ddPTM_HeLa_Curcumin_4h_R1 1 HSPEEDFRQSPQEHFR 16 1 Q8IXT5 Q8IXT5 RBM12B RNA-binding protein 12B 1 0 HSPEEDFRQS(1)PQEHFR 61.649 0.014563 8924600 1565.7 1736.9 1896.9 1662.2 1625.6 2046.9 1412.5 1032.9 2067.9 2020.3 TRUE FALSE FALSE 1441.773193 1887.029897 1967.200783 1655.322257 1606.215782 1622.349867 1452.130948 1347.826455 1841.056544 2090.505275 0.689676898 0.902666891 0.941016895 0.791828787 0.768338545 0.776056337 0.694631564 0.64473717 0.880675388 1 11.02963597 -13.52287874 0.329933889 3.462352641 0.757917541 0.288748462 0.094348354 35.08004322 0.470631192 58.13545541 0.034636598 3.00E-14 13.52287874 -2.704435099 HSPIAPSS(ph)PSPQVLAQK ddPTM_HeLa_Curcumin_4h_R1 2 HSPIAPSSPSPQVLAQK 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 HSPIAPS(0.336)S(0.633)PS(0.031)PQVLAQK;HSPIAPS(0.126)S(0.831)PS(0.043)PQVLAQK ; 109.5 0.00057284 53261000 12430.3 8964.4 9396.7 10566.1 10717.4 14511.2 12008 5176.1 13237.4 9090 TRUE FALSE FALSE 11446.42864 9739.242791 9744.949968 10522.38028 10589.602 11501.41355 12344.91216 6754.269062 11785.29034 9405.876823 1.216944348 1.035442306 1.036049073 1.118702751 1.12584953 1.222790151 1.312467981 0.718090316 1.252970941 1 13.19934672 -6.054436928 24.6301982 1.09368841 1.119838249 0 0.162849076 1997.667365 903849.3919 0.023624101 0.039176369 8.82E-07 6.054436928 0.026149839 HSPQQPS(ph)NGSLR ddPTM_HeLa_Curcumin_4h_R1 1 HSPQQPSNGSLR 12 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 0 HSPQQPS(0.912)NGS(0.088)LR 73.834 0.015186 26998000 1536.1 1395 1119 1422.8 1608.8 2638.3 2159.7 1657.9 1603.1 1256.1 TRUE FALSE FALSE 1414.516064 1515.577584 1160.471124 1416.912831 1589.616111 2091.08684 2220.295369 2163.386078 1427.243941 1299.749382 1.088299086 1.166053707 0.892842221 1.090143108 1.223017401 1.608838496 1.708248837 1.664464018 1.098091648 1 10.34401775 -5.343920949 2.135805554 1.043198673 1.69312941 0.939312783 0.068933005 0.05114092 0.449899612 0.010219814 0.029054383 4.53E-06 5.343920949 0.649930737 HSPQQPSNGS(ph)LR ddPTM_HeLa_Curcumin_4h_R1 1 HSPQQPSNGSLR 12 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 0 HSPQQPS(0.007)NGS(0.993)LR 108.06 0.0029084 23211000 3020.4 2809 2714.5 2314.6 3088.1 5166 3603.6 2971.1 2888 2474.7 TRUE FALSE FALSE 2781.332153 3051.797443 2815.101758 2305.022798 3051.276424 4094.513367 3704.707317 3876.974713 2571.193625 2560.695641 1.086162724 1.191784527 1.099350393 0.900154927 1.191581059 1.598984784 1.446758161 1.514031832 1.004099661 1 11.32232007 -5.416393259 4.255949737 1.050011712 1.509670119 0.872173952 0.080748861 0.057919286 1.773034973 0.011878363 0.027364661 3.83E-06 5.416393259 0.459658406 HSQAVEELAEQLEQTKR ddPTM_HeLa_Curcumin_4h_R1 2 HSQAVEELAEQLEQTKR 17 1 P35579 P35579 MYH9 Myosin-9 0 0 ; ; 99.991 0.00064209 21418300 4473.4 3970.2 4342.9 4533.3 4482.6 4689.2 4195.4 3271.2 4848.7 4699.3 FALSE FALSE TRUE 4119.32567 4313.366397 4503.851694 4514.542406 4429.147923 3716.607062 4313.111633 4268.573821 4316.809741 4862.600325 0.847144613 0.887049338 0.926222883 0.928421442 0.910859957 0.764325014 0.886996945 0.877837687 0.887757466 1 12.2475123 -9.381590463 0.944726903 1.005116575 0.877145602 0.043226107 0.056273111 0.426200311 0.635951126 0.03943357 0.008657613 4.15E-10 9.381590463 -0.127970973 HSQPAT(ph)PTPLQSR ddPTM_HeLa_Curcumin_4h_R1 4 HSQPATPTPLQSR 13 0 Q9NR12-2;Q9NR12 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 0 HSQPAT(0.998)PT(0.002)PLQSR;HSQPAT(0.992)PT(0.008)PLQSR;HSQPAT(0.999)PT(0.001)PLQSR;HSQPAT(0.998)PT(0.002)PLQSR ;;; 130.64 0.0015291 119331000 15619.4 13168.1 12894.7 14538.3 13025 22505.2 20272.2 12280 16744.2 12715 TRUE FALSE FALSE 14383.10801 14306.29189 13372.58893 14478.14437 12869.68538 17837.36783 20840.98337 16024.11547 14907.40315 13156.8453 1.093203399 1.087364908 1.016397823 1.100426739 0.978174105 1.355748086 1.584041075 1.217929914 1.133053008 1 13.68352599 -5.187192931 5.264799776 1.046819884 1.41397096 0.71150058 0.095278998 0.071926229 3.648412603 0.011839498 0.030883153 6.50E-06 5.187192931 0.367151076 HSQPS(ph)PEPHS(ph)PTEPPAWGSSIVK ddPTM_HeLa_Curcumin_4h_R1 1 HSQPSPEPHSPTEPPAWGSSIVK 23 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 2 0 HS(0.145)QPS(0.852)PEPHS(0.817)PT(0.179)EPPAWGS(0.003)S(0.003)IVK 46.464 0.017262 13211000 4454.7 3798.6 3605.5 3574.5 4292.8 4227 3377.6 4108.9 4769.8 3926.5 TRUE FALSE FALSE 4102.105794 4126.934058 3739.123002 3559.709666 4241.611164 3350.272552 3472.366366 5361.684695 4246.564873 4062.945583 1.00963838 1.015749282 0.920298568 0.876140129 1.043974397 0.824592031 0.854642597 1.319654567 1.045193638 1 11.98831033 -6.788331343 24.64583326 1.005518473 0.95987525 0.017186066 0.132737858 634.5514266 581548.9361 0.019863434 0.026110014 1.63E-07 6.788331343 -0.045643222 SSIT(ph)EPEGPNGPNIQK ddPTM_HeLa_Curcumin_4h_R1 1 SSITEPEGPNGPNIQK 16 0 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 0 S(0.053)S(0.053)IT(0.894)EPEGPNGPNIQK 153.81 0.00093724 11661000 2202.5 1412.5 2116.8 2089.6 2166.9 2545.7 1327.8 556.91 2070.3 1669.5 TRUE FALSE FALSE 2028.169801 1534.590206 2195.25047 2080.953789 2141.061133 2017.693124 1365.054494 726.7092953 1843.19327 1727.515001 1.174038894 0.888322362 1.270756242 1.204593759 1.239387867 1.1679743 0.790183873 0.42066743 1.066962237 1 10.75448252 -4.467211164 2.679517784 1.107792659 0.40778321 0.794436998 0.113131258 0.118039875 1.420867256 0.01732577 0.146927521 3.41E-05 4.467211164 -0.700009449 down HSS(ph)PSGTVAAR ddPTM_HeLa_Curcumin_4h_R1 1 HSSPSGTVAAR 11 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 HS(0.167)S(0.833)PSGTVAAR 74.987 0.016006 2550000 365.71 373.97 361.47 253.18 327.81 585.22 326.55 306.73 591.43 300.82 TRUE FALSE FALSE 336.7636676 406.2943004 374.8663962 252.1324082 323.9010798 463.8387752 335.7121141 400.250565 526.5516087 311.2734726 1.081890033 1.305264779 1.204299207 0.810002877 1.040567566 1.490132684 1.078511803 1.285848619 1.691604505 1 8.282038822 -1.000000003 0.097965693 0.906271601 1.877458927 0 0.274313239 181.095553 1.269416714 1.511113354 23.7411746 0.099999999 1.000000003 0.971187326 HSS(ph)YPAGTEDDEGMGEEPSPFR ddPTM_HeLa_Curcumin_4h_R1 4 HSSYPAGTEDDEGMGEEPSPFR 22 0 Q92934 Q92934 BAD Bcl2-associated agonist of cell death 1 0 HS(0.19)S(0.81)YPAGTEDDEGMGEEPSPFR;HS(0.216)S(0.784)YPAGTEDDEGMGEEPSPFR;HS(0.104)S(0.527)Y(0.368)PAGTEDDEGMGEEPSPFR;HS(0.173)S(0.827)YPAGTEDDEGMGEEPSPFR ;;; 180.05 2.41E-10 105122000 9393 7313.99 8226 8170.7 8045.1 9981.3 7423.72 5719.44 9512.9 8374.2 TRUE FALSE FALSE 8649.534139 7946.178705 8530.862796 8136.891808 7949.167437 7911.065868 7632.009603 7463.270927 8469.35867 8665.202827 0.998191769 0.917021663 0.984496609 0.939030738 0.917366575 0.912969497 0.880765258 0.861292122 0.97739878 1 13.0810178 -4.993973851 0.340042173 1.006405306 0.798100213 0.783589438 0.021733977 1.087249513 0.127825628 0.007928008 0.087079825 1.01E-05 4.993973851 -0.208305093 HSTPSNSSNPSGPPS(ph)PNSPHR ddPTM_HeLa_Curcumin_4h_R1 2 HSTPSNSSNPSGPPSPNSPHR 21 0 Q9Y5S2 Q9Y5S2 CDC42BPB Serine/threonine-protein kinase MRCK beta 1 0 HSTPSNSSNPS(0.001)GPPS(0.927)PNS(0.071)PHR;HSTPSNSSNPSGPPS(0.929)PNS(0.071)PHR ; 121.84 5.08E-06 2327100 626.31 681.8 376.59 445.14 1029.51 2565.7 432.22 634.4 883.81 913.57 TRUE FALSE FALSE 576.7369026 740.731754 390.5467567 443.2981286 1017.233766 2033.544899 444.3469299 827.8256396 786.8582542 945.3164895 0.610099273 0.783580697 0.413138627 0.468941496 1.076077459 2.151178913 0.470050967 0.875712683 0.832375467 1 9.884653611 -5.547504203 19.53551484 0.754408888 1.182343119 0.208386172 0.42732332 25.54067894 20261.12432 0.06306975 0.126163617 2.83E-06 5.547504203 0.427934231 HSTSGT(ph)DEGEDGDEPDDGSNDVVDLLPR ddPTM_HeLa_Curcumin_4h_R1 2 HSTSGTDEGEDGDEPDDGSNDVVDLLPR 28 0 Q14008-2;Q14008;Q14008-3 Q14008-2 CKAP5 Cytoskeleton-associated protein 5 1 0 HS(0.014)T(0.054)S(0.213)GT(0.719)DEGEDGDEPDDGSNDVVDLLPR;HS(0.008)T(0.035)S(0.098)GT(0.85)DEGEDGDEPDDGS(0.009)NDVVDLLPR ; 111.9 8.58E-10 32966000 1085.36 1103.6 783.53 962.28 1151.3 1236.81 1073.01 686.89 1089.5 958.13 TRUE FALSE FALSE 999.4526107 1198.990266 812.5683111 958.2983403 1137.571499 980.2816643 1103.115773 896.3195989 969.9845758 991.4249462 1.008097098 1.209360599 0.819596394 0.966586875 1.147410607 0.988760337 1.112656865 0.904072066 0.978374187 1 9.95335975 HSVGVVIGR ddPTM_HeLa_Curcumin_4h_R1 1 HSVGVVIGR 9 0 A0A087WTP3;Q92945;M0R0I5 A0A087WTP3 KHSRP Far upstream element-binding protein 2 0 0 107.69 0.0012423 2917200 1430.5 1074.3 1229.3 1442.1 1403.5 1427 1143.8 987.37 1598.4 1215.5 FALSE FALSE TRUE 1317.274416 1167.157705 1274.858939 1436.132972 1386.764179 1131.024114 1175.89195 1288.414568 1423.059519 1257.738535 1.047335658 0.927981192 1.013612054 1.141837459 1.102585427 0.899252176 0.934925596 1.024389833 1.131443046 1 10.29661632 -5.251285281 24.97733694 1.028721557 0.951062847 0.257156288 0.069765839 798.1188042 1963230.098 0.009093836 0.022871688 5.61E-06 5.251285281 -0.07765871 HSVTAAT(ph)PPPS(ph)PTSGESGDLLSNLLQSPSSAK ddPTM_HeLa_Curcumin_4h_R1 2 HSVTAATPPPSPTSGESGDLLSNLLQSPSSAK 32 0 Q96QU8-2;Q96QU8 Q96QU8-2 XPO6 Exportin-6 2 0 HS(0.01)VT(0.046)AAT(0.884)PPPS(0.28)PT(0.262)S(0.246)GES(0.233)GDLLS(0.036)NLLQS(0.002)PSSAK;HS(0.003)VT(0.024)AAT(0.875)PPPS(0.456)PT(0.371)S(0.113)GES(0.098)GDLLS(0.058)NLLQS(0.001)PSSAK ; 67.714 6.38E-05 75722600 3259.7 2448.83 2783.4 3398.1 3504.8 4205.2 2893.5 2857.5 3223.1 3168.7 TRUE FALSE FALSE 3001.691305 2660.495953 2886.555253 3384.039563 3463.007549 3332.994118 2974.683823 3728.738596 2869.533994 3278.812089 0.915481346 0.811420686 0.880366173 1.03209317 1.056177498 1.016524896 0.907244374 1.137222413 0.875174885 1 11.67895751 -6.235564927 24.05941023 0.940123759 1.023763006 0.382274008 0.074945536 588.5167713 547232.9918 0.011896543 0.01972265 5.81E-07 6.235564927 0.083639246 HSVTAATPPPS(ph)PT(ph)SGESGDLLSNLLQSPSSAK ddPTM_HeLa_Curcumin_4h_R1 1 HSVTAATPPPSPTSGESGDLLSNLLQSPSSAK 32 0 Q96QU8-2;Q96QU8 Q96QU8-2 XPO6 Exportin-6 2 0 HSVT(0.003)AAT(0.041)PPPS(0.58)PT(0.571)S(0.559)GES(0.198)GDLLS(0.048)NLLQSPSSAK 93.505 1.59E-08 62044000 2327.2 2232.8 2533 2735.2 2589.6 3358.7 2070.1 2182.9 2480.7 2043.9 TRUE FALSE FALSE 2142.999664 2425.793283 2626.875208 2723.882467 2558.720711 2662.06776 2128.181435 2848.456161 2208.573416 2114.925373 1.013274365 1.14698765 1.242065201 1.287933136 1.209839715 1.258705292 1.006267863 1.346835306 1.044279597 1 11.04639104 -7.13510425 2.796797001 1.005221862 1.218510943 0.543298776 0.083963852 0.132975395 1.999188989 0.013327533 0.016532589 7.33E-08 7.13510425 0.213289081 HTDDEMTGY(ph)VATR ddPTM_HeLa_Curcumin_4h_R1 4 HTDDEMTGYVATR 13 0 E7EX54;B4E0K5;Q16539-5;Q16539-3;Q16539-4;Q16539-2;Q16539 E7EX54 MAPK14 Mitogen-activated protein kinase 14 1 0 HTDDEMT(0.001)GY(0.994)VAT(0.005)R;HTDDEMT(0.019)GY(0.981)VATR;HTDDEMT(0.007)GY(0.989)VAT(0.004)R;HTDDEMT(0.002)GY(0.998)VATR ;;; 164.68 0.00079481 201402000 11271 8062.1 11478.5 11300.7 9821.6 10372.4 9085.3 46875.5 10456.2 8810.6 TRUE FALSE FALSE 10378.88846 8758.952 11903.90331 11253.9407 9704.483835 8221.047319 9340.209066 61167.62416 9309.18102 9116.767694 1.1384395 0.960751913 1.305715327 1.234422229 1.064465407 0.901750225 1.024508837 6.709354259 1.021105433 1 13.1543067 -4.261134863 24.99992136 1.07389758 6.709355943 0.995236271 0.116998368 1.158174758 95038.61648 0.016817793 0.131619535 5.48E-05 4.261134863 5.635458364 HTDSEPPDIDQLK ddPTM_HeLa_Curcumin_4h_R1 1 HTDSEPPDIDQLK 13 0 A0A1B0GVJ7 A0A1B0GVJ7 0 0 57.175 0.01657 16659000 7582.9 5904.3 5483.8 8630.4 5423.9 940.72 1907.5 1973.6 6365.6 6643.3 FALSE FALSE TRUE 6982.705464 6414.641383 5687.034452 8594.689692 5359.223535 745.6040679 1961.019316 2575.341555 5667.309606 6874.154181 1.01579122 0.933153551 0.827306793 1.250290504 0.779619339 0.108464845 0.28527427 0.374641227 0.824437372 1 12.74696649 -5.416235927 4.369657023 1.002268571 0.264210089 0.856793405 0.130915127 0.047606742 1.512840567 0.01577383 0.036249649 3.83E-06 5.416235927 -0.738058482 down HTENTFSRPGGR ddPTM_HeLa_Curcumin_4h_R1 2 HTENTFSRPGGR 12 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1;C9J813 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 0 0 ; ; 81.525 0.0058201 2061580 305.07 69.973 279.67 259.32 263.97 169.7 318.45 184.16 261.038 404.1 FALSE FALSE TRUE 280.9233876 76.02115433 290.0348162 258.2470026 260.8223302 134.5023071 327.3848499 240.3095362 232.4027845 418.1424449 0.671836574 0.181806835 0.693626824 0.61760533 0.623764302 0.321666238 0.782950533 0.574707349 0.555798119 1 8.707850686 -8.480277691 0.873301239 0.967242668 0.555667065 0.014688408 0.213626118 0.323310533 0.509489939 0.066406273 0.03592174 3.31E-09 8.480277691 -0.411575603 HTGMASIDSSAPETTSDS(ph)SPTLSR ddPTM_HeLa_Curcumin_4h_R1 2 HTGMASIDSSAPETTSDSSPTLSR 24 0 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2;H0YCW2;S4R3B3;H7C453;S4R3U7 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 0 HTGMASIDSSAPETT(0.01)S(0.119)DS(0.419)S(0.253)PT(0.045)LS(0.155)R;HTGMASIDSSAPETT(0.012)S(0.033)DS(0.406)S(0.252)PT(0.05)LS(0.247)R ; 153.23 7.50E-08 22039000 2519.34 2147.18 2013.32 1653.23 2986.1 3758.5 1484.69 1007.12 2912.81 2093.71 TRUE FALSE FALSE 2319.931581 2332.772672 2087.93541 1646.389372 2950.492708 2978.944733 1526.346406 1314.186252 2593.28203 2166.466267 1.070836697 1.076763902 0.963751637 0.759942307 1.36189183 1.375024748 0.704532736 0.606603607 1.197010113 1 11.08112806 -4.595147527 9.377876768 1.054346401 0.630942993 0.489491346 0.178049643 0.181275963 21.62014397 0.023924922 0.089905673 2.54E-05 4.595147527 -0.423403408 STGVSFWTQDSDENEQEQQS(ph)DTEEGSNKKETQTDSISR ddPTM_HeLa_Curcumin_4h_R1 1 STGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISR 38 2 O14974-5;O14974-4;O14974-3;O14974-2;O14974;H0YIM2;H0YIS3 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 STGVS(0.001)FWT(0.042)QDS(0.168)DENEQEQQS(0.609)DT(0.129)EEGS(0.03)NKKET(0.008)QT(0.009)DS(0.003)IS(0.001)R 52.777 0.00064204 11147000 1543.7 1211.5 1309.1 1400.8 1218.4 1577.5 1381.5 2285 1772.2 1093.6 TRUE FALSE FALSE 1421.514516 1316.216662 1357.616398 1395.003861 1203.871376 1250.308718 1420.261172 2981.685981 1577.794094 1131.602519 1.256195963 1.163143984 1.199729035 1.23276843 1.063864171 1.104900968 1.25508838 2.634923422 1.39430062 1 10.14415158 -4.260081044 4.11041199 1.135909153 2.762998792 0.939989025 0.109627889 0.034050332 1.241955182 0.014261502 0.16358105 5.49E-05 4.260081044 1.627089639 up HTGPNS(ph)PDTANDGFVRL ddPTM_HeLa_Curcumin_4h_R1 5 HTGPNSPDTANDGFVRL 17 1 E7EQJ0 E7EQJ0 HNRNPH1 1 0 HTGPNS(1)PDTANDGFVRL;HTGPNS(1)PDTANDGFVRL;HTGPNS(1)PDTANDGFVRL;HT(0.015)GPNS(0.983)PDT(0.002)ANDGFVRL;HTGPNS(1)PDTANDGFVRL ;;;; 173.03 1.91E-05 187992000 17790.2 13883.6 13369.9 20971.6 16196.2 2088.4 5736.56 9246.3 18931.6 14747.7 TRUE FALSE FALSE 16382.0869 15083.63652 13865.40026 20884.82508 16003.07089 1655.242299 5897.512434 12065.45431 16854.85084 15260.18148 1.073518485 0.988431005 0.908599958 1.368583008 1.048681558 0.108468061 0.386464109 0.790649464 1.104498716 1 13.8974845 -5.281240706 24.44081358 1.048689132 0.42432093 0.701258769 0.191594042 229.7192464 283542.6413 0.026089785 0.058418959 5.23E-06 5.281240706 -0.624368202 HTGPNSPDTANDGFVR ddPTM_HeLa_Curcumin_4h_R1 4 HTGPNSPDTANDGFVR 16 0 P31943;G8JLB6;E9PCY7;D6RBM0;D6RIH9;D6RAM1;E5RGV0;D6R9T0;D6RFM3;D6RIT2;D6RIU0;D6RDU3;D6RJ04;H0YAQ2;E5RGH4;P55795;E7EQJ0 P31943;P55795;E7EQJ0 HNRNPH1;HNRNPH2 "Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2" 0 0 ;;; ;;; 191.01 2.66E-12 32924000 6231.8 6000.2 5718.2 5521.98 8011.4 10462.5 6390.3 6365.3 7603.1 6004.8 FALSE FALSE TRUE 5738.546454 6518.830552 5930.121522 5499.13151 7915.869287 8292.459563 6569.594619 8306.050668 6769.058952 6213.466353 0.92356603 1.049145546 0.954398267 0.885034407 1.273986023 1.334594748 1.057315554 1.336782111 1.089417495 1 12.60118262 -5.755352753 24.99999656 0.964447227 1.242853307 0.665632732 0.092068833 55.56732645 228232.9257 0.01155274 0.022640641 1.76E-06 5.755352753 0.27840608 HTLGDS(ph)DNES ddPTM_HeLa_Curcumin_4h_R1 1 HTLGDSDNES 10 0 G3V1D1;G3V192;P02794 G3V1D1 FTH1 "Ferritin;Ferritin heavy chain;Ferritin heavy chain, N-terminally processed" 1 0 HT(0.001)LGDS(0.995)DNES(0.004) 97.597 0.014172 342380000 7396.1 6663.7 7626.9 6285.8 8801.7 9615.8 6776 5609.1 6880 6104.1 TRUE FALSE FALSE 6810.690881 7239.680535 7909.559623 6259.791025 8696.745476 7621.374688 6966.116323 7319.288769 6125.281213 6316.217021 1.078286395 1.146205159 1.252262169 0.991066489 1.376891492 1.206635976 1.102893758 1.158808943 0.969770543 1 12.62484503 -7.57774209 0.82690212 1.016086162 1.185171224 0.383224491 0.095582234 0.415665221 0.599195435 0.024326775 0.023917386 2.64E-08 7.57774209 0.169085062 HTNPSSSS(ph)PGTRT ddPTM_HeLa_Curcumin_4h_R1 2 HTNPSSSSPGTRT 13 1 Q8WUH2 Q8WUH2 TGFBRAP1 Transforming growth factor-beta receptor-associated protein 1 1 0 HTNPSSS(0.021)S(0.971)PGT(0.004)RT(0.004);HTNPS(0.004)S(0.008)S(0.18)S(0.769)PGT(0.017)RT(0.022) ; 118.5 0.0012396 5869000 1721.21 1704.3 1870.13 1422.37 2073.06 2856.78 1287.14 824.21 2344.87 2005.17 TRUE FALSE FALSE 1584.974412 1851.612098 1939.438663 1416.48461 2048.340113 2264.251625 1323.253684 1075.507835 2087.643628 2074.849508 0.763898493 0.892407903 0.934737028 0.682692699 0.987223461 1.091284749 0.637758873 0.518354623 1.006166288 1 11.01879098 -13.52287875 0.026508377 2.100289061 3.85E-10 0.234641593 0.157310737 2284.609262 4.871320958 279.4955395 132.2459753 3.00E-14 13.52287875 -2.10028906 HTPFYALPSSLERT(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 1 HTPFYALPSSLERTPTK 17 1 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 0 HTPFY(0.004)ALPS(0.074)S(0.074)LERT(0.615)PT(0.234)K 65.765 0.020105 22438000 1546.9 1095.8 1227.8 1464 1194.8 1561.6 1421.1 594.76 1587.6 1811.9 TRUE FALSE FALSE 1424.461233 1190.516069 1273.303348 1457.942356 1180.55279 1237.706557 1460.972241 776.0995861 1413.444252 1874.86339 0.759768013 0.634988168 0.6791446 0.777625913 0.629674032 0.660158262 0.77924197 0.413949939 0.753891862 1 10.87256976 -13.52287803 0.121553747 2.182977571 0.498372945 0.271608648 0.12100423 35.39924418 0.309909492 10.09651149 0.394105275 3.00E-14 13.52287803 -1.684604626 HTPPTIGGS(ph)LPYR ddPTM_HeLa_Curcumin_4h_R1 5 HTPPTIGGSLPYR 13 0 H7C3Q7;H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9;E9PEZ7 H7C3Q7 ABI2 Abl interactor 2 1 0 HTPPT(0.152)IGGS(0.848)LPYR;HTPPT(0.023)IGGS(0.977)LPYR;HT(0.002)PPT(0.011)IGGS(0.987)LPYR;HTPPT(0.002)IGGS(0.998)LPYR;HT(0.009)PPT(0.017)IGGS(0.973)LPYR ;;;; 104.16 0.0015771 92995000 9381.57 9465.42 8868.74 9787.78 8132.28 11483.69 8178.8 5432.28 11115.06 11197.48 TRUE FALSE FALSE 8639.008835 10283.56873 9197.423306 9747.28076 8035.307872 9101.843246 8408.275116 7088.557165 9895.765727 11586.5916 0.745603982 0.887540451 0.793798869 0.841255228 0.69350057 0.785549674 0.725690126 0.61178968 0.85407047 1 13.50016861 -13.52287875 0.159426579 1.919156107 0.681946681 0.467005192 0.075662271 27.64397964 0.294470196 7.977709504 0.128996955 3.00E-14 13.52287875 -1.237209427 HTVDDGLDIR ddPTM_HeLa_Curcumin_4h_R1 2 HTVDDGLDIR 10 0 A0A0C4DGH5;Q86VP6-2;Q86VP6 A0A0C4DGH5 CAND1 Cullin-associated NEDD8-dissociated protein 1 0 0 ; ; 135.8 0.0016763 10619200 3354.2 3068.1 3190.1 2872.2 3355.5 3623.9 2886.1 2348.8 3199.6 2987 FALSE FALSE TRUE 3088.711531 3333.292893 3308.327912 2860.315597 3315.487854 2872.26229 2967.076198 3064.938307 2848.611885 3090.798028 0.999324933 1.07845704 1.070379845 0.925429475 1.07269638 0.929294721 0.959970911 0.991633319 0.921642844 1 11.59376367 -5.234479346 24.90663433 1.009673149 0.960266782 0.148552684 0.054202086 904.6959279 835788.676 0.006312707 0.016091123 5.83E-06 5.234479346 -0.049406367 HTVLYIS(ph)PPPEDLLDNSR ddPTM_HeLa_Curcumin_4h_R1 2 HTVLYISPPPEDLLDNSR 18 0 O94916-2;O94916;O94916-4;O94916-5 O94916-2 NFAT5 Nuclear factor of activated T-cells 5 1 0 HTVLYIS(1)PPPEDLLDNSR;HTVLY(0.016)IS(0.984)PPPEDLLDNSR ; 147.28 7.53E-05 15346100 4637.6 3336.4 3723.9 4098.6 3505.4 4423.5 2856.1 2460.4 3747.9 3769.6 TRUE FALSE FALSE 4270.529066 3624.783549 3861.91101 4081.641079 3463.600394 3506.016237 2936.234479 3210.564634 3336.764747 3900.593319 1.094840891 0.929290303 0.990082968 1.046415441 0.887967576 0.898841779 0.752766115 0.823096481 0.855450562 1 11.92947787 -5.345947514 0.924870474 1.03670282 0.770790591 0.396010661 0.077843243 0.27228742 0.387084039 0.00951179 0.049685957 4.51E-06 5.345947514 -0.265912229 HVEEFS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 HVEEFSPR 8 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 1 0 HVEEFS(1)PR;HVEEFS(1)PR ; 121.83 0.0028898 4720900 2005.75 1808.7 1773.69 1806.55 1764.31 2338.1 1623.21 2093.03 2153.51 1881.94 TRUE FALSE FALSE 1846.992771 1965.035969 1839.424512 1799.074975 1743.271756 1853.151704 1668.752904 2731.185212 1917.275341 1947.337275 0.948470917 1.009088664 0.944584451 0.923864088 0.895207922 0.951633663 0.856940873 1.402522946 0.984562544 1 10.92728706 -4.253297256 24.99971403 0.959013571 1.402523164 0.898825626 0.045759656 245.9195287 755058.5242 0.006693416 0.100517051 5.58E-05 4.253297256 0.443509593 HVEEFSPR ddPTM_HeLa_Curcumin_4h_R1 4 HVEEFSPR 8 0 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 0 0 ;;; ;;; 123.98 0.0033635 17005000 4982.76 4483.45 4360.81 5158.4 4856.9 3088.35 2774.12 2621.52 4762.08 4508.03 FALSE FALSE TRUE 4588.369288 4870.97944 4522.425455 5137.055908 4798.98464 2447.791397 2851.954341 3420.80938 4239.691738 4664.683707 0.983639959 1.044225021 0.96950313 1.101265644 1.028791005 0.524749705 0.611392866 0.733342193 0.908891579 1 12.18756355 -5.268173133 24.99997648 1.004843611 0.621984711 0.873665097 0.066571559 106.5218968 395477.614 0.008261903 0.018871169 5.39E-06 5.268173133 -0.3828589 HVGNQQYNVTYVVK ddPTM_HeLa_Curcumin_4h_R1 2 HVGNQQYNVTYVVK 14 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;A0A0A0MT44 O75369-8 FLNB Filamin-B 0 0 ; ; 102.87 0.0011463 18273600 14500.9 11677.5 12564.3 12361.6 12301.3 18680.7 13393.5 14030.9 14794.4 13070.2 FALSE FALSE TRUE 13353.13846 12686.85107 13029.94401 12310.45097 12154.61503 14806.11225 13769.28556 18308.85682 13171.49133 13524.38848 0.987337689 0.938072068 0.963440531 0.910240858 0.898718271 1.094771292 1.018107812 1.353765965 0.97390661 1 13.72327574 -3.371987543 1.236355061 0.97810005 3.60643965 0.834762781 0.050912928 3.327420629 0.805462962 0.007631284 18.88470703 0.000424632 3.371987543 2.6283396 HVINFDLPSDIEEYVHR ddPTM_HeLa_Curcumin_4h_R1 1 HVINFDLPSDIEEYVHR 17 0 A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8Y5G6;A0A2R8YFR4;A0A0D9SFB3;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;A0A0D9SF53;A0A2R8YF78;F6S8Q4;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;O15523-2;O15523;A0A0J9YVQ7;A0A087WVZ1 A0A2R8YCW1 DDX3X;DDX3Y ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 0 0 149.6 6.65E-05 50239000 2720.1 2202.8 2620.1 2228.5 2365.6 3441.3 2412.4 2370.9 2634.7 2470.2 FALSE FALSE TRUE 2504.801215 2393.200217 2717.203211 2219.279057 2337.391765 2727.535589 2480.085451 3093.776496 2345.680002 2556.039266 0.979954122 0.93629243 1.063052218 0.868249204 0.914458473 1.067094557 0.970284567 1.210379096 0.917701083 1 11.31969428 -3.099197421 1.51393828 0.980616681 6.549985698 0.562218116 0.06242098 19.25590238 2.162746785 0.008080185 335.3943326 0.000795798 3.099197421 5.569369017 HVIPMNPNTDDLFK ddPTM_HeLa_Curcumin_4h_R1 1 HVIPMNPNTDDLFK 14 0 P13797;A0A0A0MSQ0;P13797-3;P13797-2;U3KQI3 P13797 PLS3 Plastin-3 0 0 78.287 0.0075213 2189500 2729.3 1761.7 1829.3 1970.8 2093.3 2234.6 2425.3 2379.2 1787.8 2048.4 FALSE FALSE TRUE 2513.273025 1913.973498 1897.095467 1962.645352 2068.338765 1771.118771 2493.347391 3104.607128 1591.682813 2119.581748 1.185740077 0.902995839 0.895032933 0.925958791 0.975824012 0.835598237 1.176339338 1.464726299 0.750941932 1 11.04956389 -4.374871241 3.492466206 1.028904091 1.473665093 0.518899857 0.137999059 0.159823557 3.118426259 0.018463954 0.151331011 4.22E-05 4.374871241 0.444761002 HVLEDS(ph)PAGK ddPTM_HeLa_Curcumin_4h_R1 1 HVLEDSPAGK 10 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970;B7ZB24;H0YGQ3;F5H8D6;F8WDQ8 F5H1U9 MPDZ Multiple PDZ domain protein 1 0 HVLEDS(1)PAGK 84.289 0.012543 7480700 4706.1 3593 3885.6 4743.9 4586 7763.4 6522.5 2673.3 5124.2 3065 TRUE FALSE FALSE 4333.607219 3903.56291 4029.603754 4724.270999 4531.314945 6153.183328 6705.503796 3488.376864 4562.08808 3171.508522 1.36641828 1.230822141 1.270563748 1.489597447 1.428756982 1.940144031 2.114294743 1.099910922 1.438459978 1 11.6309535 -6.754094717 0.270345518 0.975987529 1.846274776 0.181166223 0.299368369 1.588005121 0.329000736 0.295186266 0.52151903 1.76E-07 6.754094717 0.870287247 HVLS(ph)DLEDDEVRDLGSTGTSSVQR ddPTM_HeLa_Curcumin_4h_R1 1 HVLSDLEDDEVRDLGSTGTSSVQR 24 1 H0YDJ4;H9KV85;E9PN67;C9J066;Q8N4C6-4;Q8N4C6-9;Q8N4C6-2;Q8N4C6;Q8N4C6-5;Q8N4C6-10;Q8N4C6-7 H0YDJ4 NIN Ninein 1 0 HVLS(0.995)DLEDDEVRDLGS(0.001)T(0.003)GTSSVQR 51.773 0.0079759 1653500 451.01 456.83 431.21 386.7 403.65 585 378.85 374.58 609.27 400.12 TRUE FALSE FALSE 415.3120826 496.3163496 447.1910219 385.0999379 398.8367374 463.6644057 389.4795114 488.7877176 542.4346053 414.0241402 1.003110791 1.198761863 1.08010857 0.930138851 0.963317591 1.119897032 0.940716914 1.180577822 1.310152121 1 8.693571078 -1.211232738 0.00774085 3.04E-08 2.171000342 0 0.134602478 45762.25268 28.59702034 3591.864747 4474.290046 0.061484729 1.211232738 2.171000312 HVLTGSADNSCR ddPTM_HeLa_Curcumin_4h_R1 2 HVLTGSADNSCR 12 0 Q13347;Q5TFK1 Q13347 EIF3I Eukaryotic translation initiation factor 3 subunit I 0 0 ; ; 166.29 5.13E-07 2143280 806.18 747.4 789.42 837.53 857.12 1267.97 821.66 807.32 980.47 759.57 FALSE FALSE TRUE 742.3700023 812.0019257 818.6765996 834.0645228 846.8994038 1004.978729 844.7135682 1053.468152 872.914894 785.965001 0.944533155 1.033127333 1.041619663 1.061198045 1.077528138 1.278655828 1.074747053 1.340349952 1.1106282 1 9.61832126 -5.320994862 0.597945187 0.97347056 1.29736919 0.528604667 0.07958314 0.545974789 0.26283832 0.012678574 0.097032353 4.78E-06 5.320994862 0.323898629 HVLVTLGEK ddPTM_HeLa_Curcumin_4h_R1 2 HVLVTLGEK 9 0 P60660-2;F8W1R7;G8JLA2;G3V1V0;P60660;G3V1Y7;J3KND3;B7Z6Z4;F8VZU9;F8VPF3;F8W180;F8VXL3;H0YI43 P60660-2 MYL6 Myosin light polypeptide 6 0 0 ; ; 120.12 0.0003816 61156000 31597 20171.9 27481 24071 28666 33635 27710 25406 26203 26370 FALSE FALSE TRUE 29096.06411 21915.46915 28499.47003 23971.40058 28324.17667 26658.72186 28487.46802 33152.17245 23328.59646 27286.35554 1.066322839 0.803165858 1.044458649 0.878512359 1.038034436 0.976998259 1.044018795 1.214972531 0.854954647 1 14.7358921 -4.279100875 3.061867399 1.003265778 1.244021676 0.346160504 0.09234581 0.278947899 3.968193565 0.011099627 0.158613757 5.26E-05 4.279100875 0.240755899 AHT(ph)PLNTPDPSTK ddPTM_HeLa_Curcumin_4h_R1 1 AHTPLNTPDPSTK 13 0 Q9BYW2;H7C3H4;A0A1W2PPX9 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 0 AHT(1)PLNTPDPSTK 108.96 0.0040586 77840000 12164 9933.7 9244.1 9898.9 9444.9 8947.3 6290.9 1751.6 11731 9420.1 TRUE FALSE FALSE 11201.20656 10792.32476 9586.694478 9857.940975 9332.275736 7091.529123 6467.405723 2285.654777 10444.13865 9747.447774 1.149142506 1.107194931 0.983508165 1.011335603 0.957407103 0.727526763 0.663497345 0.234487512 1.071474184 1 13.2508088 -4.465992443 0.818063202 1.070276934 5.92E-18 0.945668639 0.061439048 0.34268794 0.199874754 0.011787742 0.309573961 3.42E-05 4.465992443 -1.070276934 down HVSMDQGTLAGILIGLAQLNCS(ph)ELKLKRLS(ph)YR ddPTM_HeLa_Curcumin_4h_R1 1 HVSMDQGTLAGILIGLAQLNCSELKLKRLSYR 32 3 Q96BY7 Q96BY7 ATG2B Autophagy-related protein 2 homolog B 2 0 HVSMDQGT(0.003)LAGILIGLAQLNCS(0.996)ELKLKRLS(0.552)Y(0.449)R 41.818 0.010589 19872000 2339.1 2037.9 2059.6 1947.6 2423.8 2867.6 2390.6 2054.5 2196.6 2033.8 TRUE FALSE FALSE 2153.957767 2214.046995 2135.930588 1939.541347 2394.897768 2272.827435 2457.673802 2680.907592 1955.638476 2104.474399 1.023513409 1.052066491 1.01494729 0.921627437 1.138002805 1.079997664 1.167832597 1.27390839 0.929276439 1 11.03924424 -4.255776736 0.764560136 1.010618774 1.434832152 0.739895296 0.052786943 0.860457935 0.353051265 0.007202269 0.31211977 5.55E-05 4.255776736 0.424213378 HVTLGPGQS(ph)PLSR ddPTM_HeLa_Curcumin_4h_R1 1 HVTLGPGQSPLSR 13 0 O15061 O15061 SYNM Synemin 1 0 HVTLGPGQS(0.986)PLS(0.014)R 84.403 0.008435 2969200 1009.1 792.86 915.3 660.73 979.06 1424.4 1143.3 845.02 1348 716.81 TRUE FALSE FALSE 929.2286702 861.3912855 949.2218232 657.9960743 967.3853489 1128.963384 1175.377921 1102.662708 1200.127773 741.7190941 1.25280403 1.161344358 1.279759185 0.887123009 1.304247601 1.522090226 1.584667201 1.486631147 1.618035429 1 9.534729099 -1 0.231989403 1.055968402 4.241078503 0.096400369 0.222473988 27.59581596 0.336662247 0.101041001 33.82414071 0.1 1 3.185110101 HVTLPS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 HVTLPSSPR 9 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;X6RE05;A0A0A0MSW0 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 0 HVTLPS(0.6)S(0.4)PR;HVTLPS(0.612)S(0.388)PR ; 116.74 0.0033454 92261000 10105.8 9650.5 8553.7 8333 11111.5 15777.3 8484 7909.1 12565.9 10755 TRUE FALSE FALSE 9305.915266 10484.64622 8870.707647 8298.520254 10979.00262 12504.91013 8722.038206 10320.54818 11187.45221 11128.73545 0.836205992 0.942123772 0.797099337 0.745684026 0.986545387 1.123659574 0.783740277 0.927378338 1.005276139 1 13.44200205 -3.855491318 19.27064877 0.911201556 10.78447672 0.001025448 0.114364574 7758.168047 1009731.541 0.015784653 81484.04387 0.000139479 3.855491318 9.873275167 HVTLPSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 HVTLPSSPR 9 0 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;X6RE05;A0A0A0MSW0 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 0 HVTLPS(0.327)S(0.673)PR;HVTLPS(0.227)S(0.773)PR ; 120.03 0.002942 31595000 5504.3 5754.9 4722.5 4602.5 6688.1 8747.6 5453.1 4164.5 7267.9 5634.6 TRUE FALSE FALSE 5068.628847 6252.327913 4897.520004 4583.456075 6608.348776 6933.249154 5606.09931 5434.236879 6470.629553 5830.401931 0.869344671 1.072366534 0.839996978 0.786130378 1.133429368 1.189154579 0.961528789 0.932051845 1.109808488 1 12.50937963 -5.740675794 24.99989796 0.93033433 1.057084056 0.16018052 0.117451248 278.047832 334775.0239 0.015859926 0.031691921 1.82E-06 5.740675794 0.126749726 HWDQDDDFEFTGSHLTVR ddPTM_HeLa_Curcumin_4h_R1 1 HWDQDDDFEFTGSHLTVR 18 0 R4GMQ1;O60341;O60341-2 R4GMQ1 KDM1A Lysine-specific histone demethylase 1A 0 0 48.555 0.01563 2171400 898.02 900.19 1053.6 916.22 915.39 1324.3 1009.2 983.22 1143.6 992.28 FALSE FALSE TRUE 826.9407694 977.9984124 1092.647343 912.4289244 904.4745721 1049.625252 1037.515436 1282.999252 1018.149941 1026.761656 0.805387272 0.952507728 1.064168433 0.888647252 0.880900223 1.022267676 1.010473492 1.249558984 0.991612742 1 10.00388561 -1.000004804 0.790811859 0.917777989 79.15751903 0.58247861 0.074231993 259.2985091 0.884512504 0.014204728 36338.22104 0.099998894 1.000004804 78.23974104 HWDQNER ddPTM_HeLa_Curcumin_4h_R1 2 HWDQNER 7 0 F5GZI0;F5GZS6;J3KPF3;P08195-2;P08195-3;P08195;P08195-4 F5GZI0 SLC3A2 4F2 cell-surface antigen heavy chain 0 0 ; ; 110.12 0.012757 19369100 2761.6 3121.2 3168.8 3583.4 2763.2 4503.1 2307.7 1655.53 4369.6 3226 FALSE FALSE TRUE 2543.016446 3390.98262 3286.238516 3568.57284 2730.250645 3569.1063 2372.447851 2160.293476 3890.265812 3338.10326 0.761814794 1.01584114 0.98446281 1.069042076 0.81790479 1.069201886 0.710717334 0.647161968 1.165412065 1 11.70481287 -4.615873046 7.043027853 0.91888805 0.66301341 0.419086885 0.12707015 0.147740639 9.25969954 0.016455455 0.062672223 2.42E-05 4.615873046 -0.255874641 HWELTAEGEEIAR ddPTM_HeLa_Curcumin_4h_R1 2 HWELTAEGEEIAR 13 0 K7ER00;Q9Y285-2;Q9Y285;K7EK06;K7ER16 K7ER00 FARSA Phenylalanine--tRNA ligase alpha subunit 0 0 ; ; 205.31 4.53E-09 7920600 3982 3208.7 3427.2 3209.9 3876.6 4481.2 3186.2 3182 4026.3 3285.6 FALSE FALSE TRUE 3666.820498 3486.04573 3554.215047 3196.618284 3830.374077 3551.748606 3275.596197 4152.177152 3584.624963 3399.774355 1.078548196 1.025375618 1.045426748 0.940244249 1.126655383 1.044701276 0.963474588 1.221309628 1.054371434 1 11.73122328 -1.000000003 0.006706762 1.62E-08 2.194682344 0.068448085 0.073975977 54976.9558 28.79518909 4268.815707 5197.311987 0.099999999 1.000000003 2.194682327 HWILPQDYDHAQAEAR ddPTM_HeLa_Curcumin_4h_R1 1 HWILPQDYDHAQAEAR 16 0 Q15293;Q15293-2 Q15293 RCN1 Reticulocalbin-1 0 0 69.261 0.0076187 11447000 1435.7 1154.3 1512.5 1122 1300.3 1119.4 950.35 566.56 1263.4 1310.9 FALSE FALSE TRUE 1322.06283 1254.072549 1568.554581 1117.357461 1284.794772 887.2238218 977.0142633 739.3015359 1124.808181 1356.453677 0.974646501 0.924522945 1.15636428 0.82373433 0.947171874 0.654076019 0.720271012 0.545025273 0.829227123 1 10.40562407 -5.21538655 1.133428415 0.991428766 0.58421866 0.665200508 0.099494739 0.187788426 0.412407436 0.01183285 0.059961003 6.09E-06 5.21538655 -0.407210106 HWPFMVVNDAGRPK ddPTM_HeLa_Curcumin_4h_R1 5 HWPFMVVNDAGRPK 14 1 P11142;E9PKE3;E9PNE6;P11142-2;E9PN89;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 ;;;; ;;;; 112.5 0.001197 66573400 20877.6 17517.8 19452.9 18720.3 18961.6 30183.1 22187.1 19400.3 22521.7 21140.5 FALSE FALSE TRUE 19225.11593 19031.96057 20173.84159 18642.84036 18735.4953 23922.78483 22809.61031 25315.36216 20051.12586 21875.1308 0.878857187 0.870027281 0.922227244 0.852239035 0.856474664 1.093606481 1.042718808 1.157266779 0.916617415 1 14.41700402 -5.247053432 24.21264285 0.922438993 1.092349537 0.747388617 0.051627876 287.1646139 483318.0888 0.009276382 0.023520815 5.66E-06 5.247053432 0.169910544 HWPFQVINDGDK(ac)PK ddPTM_HeLa_Curcumin_4h_R1 1 HWPFQVINDGDKPK 14 1 A0A0G2JIW1;P0DMV9;P0DMV8 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 1 HWPFQVINDGDK(1)PK 144.51 0.0012677 1097700 566.48 877.15 684.32 693.42 1277.7 1038.7 870.74 797.9 1215.3 596.89 FALSE TRUE FALSE 521.6425103 952.9669375 709.6815012 690.5508118 1262.464262 823.2619114 895.1706209 1041.176037 1081.984631 617.6318831 0.844584816 1.542936762 1.149036377 1.118062119 2.04403998 1.332932988 1.449359474 1.685755003 1.751827683 1 9.270603418 -6.675428931 0.894514764 0.927712127 1.568661818 0 0.368116905 0.317774958 0.508549651 0.051786196 0.087174702 2.11E-07 6.675428931 0.640949691 HWPFQVINDGDKPK ddPTM_HeLa_Curcumin_4h_R1 3 HWPFQVINDGDKPK 14 1 A0A0G2JIW1;P0DMV9;P0DMV8 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 0 ;; ;; 90.913 0.002322 29561600 19430.5 14137.9 16744.4 15418.5 15178.7 18615.2 15563.8 13719 15492.5 13302.1 FALSE FALSE TRUE 17892.55542 15359.91708 17364.96219 15354.70233 14997.70392 14754.19768 16000.47834 17901.85995 13793.01151 13764.34698 1.299920399 1.115920508 1.261589977 1.115541649 1.08960519 1.071914105 1.162458223 1.300596386 1.00208252 1 13.74864855 -9.596804954 1.404734207 1.000417061 1.187143551 0.428487061 0.080571905 0.357024594 1.268496249 0.062149393 0.014530149 2.53E-10 9.596804954 0.186726491 HWVAPGGPYSAETPGVPS(ph)PIAALK ddPTM_HeLa_Curcumin_4h_R1 2 HWVAPGGPYSAETPGVPSPIAALK 24 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 0 HWVAPGGPYSAET(0.001)PGVPS(0.999)PIAALK;HWVAPGGPYSAETPGVPS(1)PIAALK ; 142.23 4.65E-07 223000000 10226.1 7550.1 7635.7 8210.9 8828.9 13260.4 10194.1 6428.5 10375.8 8273.9 TRUE FALSE FALSE 9416.693394 8202.697001 7918.685759 8176.925471 8723.621134 10510.04356 10480.11901 8388.520057 9237.600699 8561.417409 1.099898877 0.958100348 0.924926958 0.955090154 1.018945896 1.227605554 1.224110274 0.979805055 1.078980297 1 13.06363395 -5.28426893 23.82857089 1.0232209 1.151867288 0.355815034 0.082855925 383.5766183 400361.6025 0.012569722 0.028129831 5.20E-06 5.28426893 0.128646388 HYDDFFER ddPTM_HeLa_Curcumin_4h_R1 1 HYDDFFER 8 0 Q9NRL2;Q9NRL2-2 Q9NRL2 BAZ1A Bromodomain adjacent to zinc finger domain protein 1A 0 0 166.52 0.00054051 3553500 1030.1 864.94 743.13 973.12 872.7 810.27 791.84 593.24 1023.4 852.96 FALSE FALSE TRUE 948.566498 939.7015595 770.6710515 969.0934873 862.2936225 642.2108684 814.0568993 774.1161451 911.1355804 882.6002965 1.074740743 1.064696628 0.873182407 1.097998144 0.976992219 0.727635002 0.922339254 0.877085752 1.032330925 1 9.785616422 -5.505889101 22.5279433 1.029316695 0.850678779 0.547507683 0.073655291 110.0588694 145934.9524 0.010226768 0.022312163 3.12E-06 5.505889101 -0.178637916 HYEDGYPGGSDNYGS(ph)LSR ddPTM_HeLa_Curcumin_4h_R1 2 HYEDGYPGGSDNYGSLSR 18 0 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12 O60716 CTNND1 Catenin delta-1 1 0 HYEDGYPGGSDNYGS(0.992)LS(0.008)R;HYEDGYPGGSDNYGS(0.999)LS(0.001)R ; 324.45 4.71E-132 87771000 6153.9 5871.8 5518.7 5665.2 6812.5 10360.7 8857.5 6560.5 7582.7 6044.2 TRUE FALSE FALSE 5666.812321 6379.332228 5723.227877 5641.758903 6731.265387 8211.774031 9106.017611 8560.766249 6750.896781 6254.2355 0.906075942 1.020001922 0.915096318 0.90207011 1.076273093 1.312994055 1.455976132 1.368794995 1.079411989 1 12.61061783 -5.286613841 2.338877411 0.953472563 1.410918556 0.905424192 0.059359234 0.048444671 0.513545411 0.007150108 0.020479096 5.17E-06 5.286613841 0.457445993 HYELYR ddPTM_HeLa_Curcumin_4h_R1 1 HYELYR 6 0 Q92599;B1AMS2;F8W8I8;A6NFQ9;D6RER5;A6NMH6;A0A087X142;D6RGI3;D6RDU5;H0Y961;Q92599-2;Q14141-4;Q92599-3;Q14141-2;Q9P0V9-3;Q14141;Q9NVA2-2;Q92599-4;Q9NVA2;E7EW69;E7EX04;B5ME97;Q9P0V9;Q9P0V9-2 Q92599;E7EW69 SEPT8;SEPT6;SEPT11;SEPT10 Septin-8;Septin-6;Septin-10;Septin-11 0 0 105.42 0.0060732 0 551.58 419.24 407.6 484.92 577.39 483.88 454.25 373.49 686.21 320.7 FALSE FALSE TRUE 507.921861 455.4772375 422.7060146 482.9135295 570.5050014 383.5178335 466.9950324 487.3653817 610.9344798 331.8443011 1.530602934 1.372563084 1.273808268 1.455241292 1.719194813 1.155716197 1.407271515 1.468656777 1.841027487 1 8.374362688 -9.372120551 0.963040091 0.985655013 1.426217041 0 0.296415194 0.355375168 0.558454745 0.113699444 0.02581138 4.25E-10 9.372120551 0.440562028 HYFQNTQGLIFVVDSNDRER ddPTM_HeLa_Curcumin_4h_R1 1 HYFQNTQGLIFVVDSNDRER 20 1 C9JPM4;P18085;C9JAK5;F5H0C7;F5H423;P84077;P61204;C9J1Z8;P84085 C9JPM4;F5H423 ARF4;ARF3;ARF1;ARF5 ADP-ribosylation factor 4;ADP-ribosylation factor 1;ADP-ribosylation factor 3;ADP-ribosylation factor 5 0 0 80.508 0.0012238 16067000 2462 2478.9 2313.3 2083.6 2322.5 4407.7 3057.5 2419.4 3580.5 3032.3 FALSE FALSE TRUE 2267.130102 2693.16507 2399.032933 2074.978615 2294.805704 3493.493335 3143.285221 3157.063922 3187.728108 3137.672199 0.722551611 0.858332196 0.764590047 0.66131147 0.731372036 1.113402903 1.001788913 1.00618029 1.015953199 1 11.61547892 -5.257100858 24.97711348 0.833403461 1.036590525 0.439095829 0.112599217 333.4204206 1919510.182 0.018801233 0.04614092 5.53E-06 5.257100858 0.203187064 HYGDQVDR ddPTM_HeLa_Curcumin_4h_R1 1 HYGDQVDR 8 0 E7ES68;G5E9D5;Q9BQ52-3;Q9BQ52-4;Q9BQ52;Q9BQ52-2 E7ES68 ELAC2 Zinc phosphodiesterase ELAC protein 2 0 0 143.73 0.0021026 3439200 389.74 354.81 514.21 411.75 647.23 565.5 369.97 494.21 604.95 697.14 FALSE FALSE TRUE 358.8916677 385.4781954 533.2670749 410.0462876 639.512205 448.2089255 380.3503625 644.8923539 538.5884985 721.3655631 0.497517051 0.534372883 0.739246649 0.568430638 0.886529989 0.621333965 0.527264375 0.893988273 0.746623524 1 9.494586742 -9.461856292 1.203793103 0.999587242 0.640416637 0.163790206 0.15515512 0.316581698 0.822195996 0.09352402 0.023225058 3.45E-10 9.461856292 -0.359170605 HYGIT(ph)SPISLAAPK ddPTM_HeLa_Curcumin_4h_R1 1 HYGITSPISLAAPK 14 0 G3XAH6;P51003;G3V457;G3V3I9;A0A0C4DGK1;P51003-2 G3XAH6 PAPOLA Poly(A) polymerase alpha 1 0 HYGIT(0.492)S(0.492)PIS(0.015)LAAPK 209.25 5.96E-09 27054000 3898.6 3274.4 3371.1 3137.2 3481.5 4804.8 3242.4 3443.2 3757.9 2989.4 TRUE FALSE FALSE 3590.021696 3557.424546 3496.035932 3124.219098 3439.985386 3808.230319 3333.373018 4493.015829 3345.667772 3093.281427 1.160586833 1.150048784 1.130202994 1.01000157 1.112082902 1.231129597 1.077617118 1.452507939 1.081591782 1 11.59492238 HYGITS(ph)PISLAAPK ddPTM_HeLa_Curcumin_4h_R1 1 HYGITSPISLAAPK 14 0 G3XAH6;P51003;G3V457;G3V3I9;A0A0C4DGK1;P51003-2 G3XAH6 PAPOLA Poly(A) polymerase alpha 1 0 HYGIT(0.025)S(0.938)PIS(0.037)LAAPK 112.5 0.002592 31439000 4067.5 3298 3455.2 3429.9 3763.8 5471.5 3688 4039.6 3943.4 3483.5 TRUE FALSE FALSE 3745.553083 3583.064424 3583.252752 3415.707983 3718.919143 4336.649223 3791.475354 5271.255444 3510.818886 3604.551366 1.039117688 0.994038942 0.994091189 0.94760974 1.031728713 1.203103738 1.051857768 1.462388772 0.973996076 1 11.81560399 -1 0.871214645 1.013098906 177.6512664 0.818752503 0.062433384 211.6596861 0.505551361 0.009023057 74238.11026 0.1 1 176.6381675 HYNGEAYEDDEHHPR ddPTM_HeLa_Curcumin_4h_R1 7 HYNGEAYEDDEHHPR 15 0 P31689 P31689 DNAJA1 DnaJ homolog subfamily A member 1 0 0 ;;;;;; ;;;;;; 94.717 0.0015257 186331900 12613.12 11249.92 11108.66 12317.85 11604.15 13250.95 9847.97 9097.43 13080.85 12078.72 FALSE FALSE TRUE 11614.77824 12222.31296 11520.35671 12266.882 11465.77809 10502.5536 10124.27753 11871.19453 11645.91348 12498.45462 0.929297149 0.977905935 0.921742492 0.9814719 0.917375663 0.840308176 0.810042348 0.949812988 0.931788276 1 13.6094621 -5.502225705 3.899332751 0.963818309 0.861933656 0.487412894 0.040966312 0.127567477 4.269818651 0.006086328 0.013592896 3.15E-06 5.502225705 -0.101884653 IAAPELHKGDS(ph)DS(ph)EEDEPTK ddPTM_HeLa_Curcumin_4h_R1 1 IAAPELHKGDSDSEEDEPTK 20 1 Q92733 Q92733 PRCC Proline-rich protein PRCC 2 0 IAAPELHKGDS(0.998)DS(0.999)EEDEPT(0.003)K 63.46 0.0087494 18852000 2532 2245 2241.9 2442.9 2627.6 2962.7 2288.2 2412.9 2347.3 2119 TRUE FALSE FALSE 2331.589528 2439.047796 2324.986786 2432.791927 2596.267586 2348.202623 2352.400734 3148.582102 2089.807063 2192.635092 1.063373261 1.112381994 1.060361934 1.109528866 1.184085576 1.070950033 1.072864674 1.435980895 0.95310299 1 11.09845002 -1.946238781 1.32188886 1.054354295 199.9999996 0.74939421 0.062500954 275.4469556 1.192634801 0.009320634 165403.3473 0.011317779 1.946238781 198.9456453 IAAPELHKGDS(ph)DS(ph)EEDEPTKK ddPTM_HeLa_Curcumin_4h_R1 1 IAAPELHKGDSDSEEDEPTKK 21 2 Q92733 Q92733 PRCC Proline-rich protein PRCC 2 0 IAAPELHKGDS(0.998)DS(0.997)EEDEPT(0.005)KK 57.616 0.0063637 33428000 2362.1 2568.5 2675.3 2088.2 2445.2 2489.8 2309.8 2467.7 2213.3 2517.1 TRUE FALSE FALSE 2175.137293 2790.509695 2774.448971 2079.559582 2416.042587 1973.387414 2374.606771 3220.09037 1970.506527 2604.569038 0.835123685 1.071390182 1.065223817 0.798427514 0.927617027 0.7576637 0.911708132 1.236323677 0.75655761 1 11.34682896 -9.833752497 1.896153517 1.000335948 0.922966125 0 0.157745898 1.107049208 7.207845158 0.103350546 0.021077393 1.47E-10 9.833752497 -0.077369823 IAAS(ph)FLK ddPTM_HeLa_Curcumin_4h_R1 1 IAASFLK 7 0 Q68EM7-5;I3L460 Q68EM7-5 ARHGAP17 Rho GTPase-activating protein 17 1 0 IAAS(1)FLK 111.69 0.015545 8291700 1361.8 866.66 1304.1 1267 1415.5 1462.8 1324.2 973.81 1063.7 1428.6 TRUE FALSE FALSE 1254.012093 941.5702286 1352.431093 1261.75749 1398.621087 1159.398791 1361.353488 1270.720186 947.0147712 1478.243744 0.848312126 0.636951946 0.914890456 0.85355172 0.946136991 0.784308268 0.920926264 0.859614791 0.640635061 1 10.52966846 -8.981032928 0.987426839 0.992814716 0.847686516 0 0.137833882 0.459506754 0.863589417 0.041405336 0.015660346 1.04E-09 8.981032928 -0.1451282 IAASS(ph)SFR ddPTM_HeLa_Curcumin_4h_R1 1 IAASSSFR 8 0 Q99961-3;Q99961-2;Q99961 Q99961-3 SH3GL1 Endophilin-A2 1 0 IAAS(0.087)S(0.604)S(0.309)FR 91.087 0.02027 118220000 6875.7 4197.8 5772.3 5850.5 6228.5 7215.8 5283.1 3519.4 5465.1 4598.5 TRUE FALSE FALSE 6331.48109 4560.639127 5986.226516 5826.292181 6154.229205 5719.161741 5431.329567 4592.448859 4865.592203 4758.297533 1.330618997 0.958460268 1.258060572 1.2244489 1.293367883 1.201934453 1.141443874 0.965145375 1.022548962 1 12.21622977 -4.273316529 3.727065251 1.169616459 0.94593359 0.184614696 0.12171552 0.368173406 9.630571187 0.019404112 0.222377955 5.33E-05 4.273316529 -0.223682869 IAASSS(ph)FR ddPTM_HeLa_Curcumin_4h_R1 2 IAASSSFR 8 0 Q99961-3;Q99961-2;Q99961 Q99961-3 SH3GL1 Endophilin-A2 1 0 IAAS(0.012)S(0.075)S(0.914)FR;IAASS(0.019)S(0.981)FR ; 173.24 0.00060619 861729000 23814.5 16186.5 20357.5 21233.3 21682.1 24169.8 22799.7 12501.8 19903.2 15693.2 TRUE FALSE FALSE 21929.5572 17585.58893 21111.96686 21145.44223 21423.55512 19156.71103 23439.39822 16313.54127 17719.86876 16238.53753 1.350463806 1.082953985 1.300115039 1.302176516 1.319303236 1.17970667 1.443442685 1.004618873 1.091223192 1 13.98713409 -9.445169947 1.063208706 0.993188777 1.261739815 0.278414586 0.12604426 0.422959805 0.819325241 0.088589667 0.019899773 3.59E-10 9.445169947 0.268551039 IAAYK(ac)SILQER ddPTM_HeLa_Curcumin_4h_R1 1 IAAYKSILQER 11 1 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 1 IAAYK(1)SILQER 163.9 3.52E-08 1465400 65.501 74.759 66.69 134.85 0 227.97 129.8 136.34 180.79 0 FALSE TRUE FALSE 60.31652673 81.22083484 69.16159007 134.2920264 0 180.6864522 133.4418387 177.9094384 160.9577893 0 0 IACDEEFS(ph)DS(ph)EDEGEGGR ddPTM_HeLa_Curcumin_4h_R1 1 IACDEEFSDSEDEGEGGR 18 0 Q92769-3;Q92769 Q92769-3 HDAC2 Histone deacetylase 2 2 0 IACDEEFS(1)DS(1)EDEGEGGR 107.63 0.0010694 0 966.28 919.32 1056.6 754.6 821.15 952.59 854.7 804.54 882.77 802.32 TRUE FALSE FALSE 889.7979184 998.7819244 1095.758525 751.4776651 811.3583226 755.0120961 878.6805817 1049.840542 785.9323396 830.2005603 1.071786699 1.20306101 1.319872062 0.905176052 0.977303993 0.909433373 1.058395554 1.264562556 0.946677679 1 9.697316095 -8.72508873 1.176899906 1.008622015 1.080943859 0.090448738 0.134736468 1.182469159 3.280649561 0.049296587 0.026367679 1.88E-09 8.72508873 0.072321844 IACDEEFS(ph)DS(ph)EDEGEGGRR ddPTM_HeLa_Curcumin_4h_R1 4 IACDEEFSDSEDEGEGGRR 19 1 Q92769-3;Q92769 Q92769-3 HDAC2 Histone deacetylase 2 2 0 IACDEEFS(1)DS(1)EDEGEGGRR;IACDEEFS(1)DS(1)EDEGEGGRR;IACDEEFS(1)DS(1)EDEGEGGRR;IACDEEFS(1)DS(1)EDEGEGGRR ;;; 88.427 0.0031173 164789000 7369.8 6293.4 6354.7 6423.2 6283.8 8137.2 5505.65 5507.02 7417.8 6308.5 TRUE FALSE FALSE 6786.472553 6837.373453 6590.210772 6396.6225 6208.869789 6449.452995 5660.123721 7186.085047 6604.085898 6527.719905 1.039639055 1.047436709 1.009573154 0.979916815 0.951154443 0.988010069 0.86709047 1.100856831 1.011698724 1 12.67236344 -6.270175144 3.309010859 1.021581681 0.969535395 0.137126231 0.054811899 0.32289107 7.405618075 0.007780431 0.012778597 5.37E-07 6.270175144 -0.052046287 IACEEEFS(ph)DS(ph)EEEGEGGRK ddPTM_HeLa_Curcumin_4h_R1 3 IACEEEFSDSEEEGEGGRK 19 1 Q13547 Q13547 HDAC1 Histone deacetylase 1 2 0 IACEEEFS(1)DS(1)EEEGEGGRK;IACEEEFS(1)DS(1)EEEGEGGRK;IACEEEFS(1)DS(1)EEEGEGGRK ;; 62.709 0.0075071 1077145000 28002.2 24580.1 23290.5 26477.6 24857.2 30188.3 22476.9 18832.7 28001.6 23164.4 TRUE FALSE FALSE 25785.79632 26704.69432 24153.66642 26368.04271 24560.79412 23926.90629 23107.54132 24574.70353 24929.89454 23969.36118 1.075781542 1.114117899 1.007689201 1.100072819 1.024674539 0.998228785 0.964044938 1.025254839 1.040073382 1 14.54890384 -5.366300307 3.839775091 1.045292506 0.992512073 0.316360981 0.037656569 0.272652364 7.196369007 0.006244213 0.014789988 4.30E-06 5.366300307 -0.052780433 IACEEEFS(ph)DSEEEGEGGRK ddPTM_HeLa_Curcumin_4h_R1 1 IACEEEFSDSEEEGEGGRK 19 1 Q13547 Q13547 HDAC1 Histone deacetylase 1 1 0 IACEEEFS(0.5)DS(0.5)EEEGEGGRK 64.318 0.0073772 53664000 2129.5 1629.3 1775.6 1999.9 1576.6 2296 1560.1 2667.5 2339.9 2108.4 TRUE FALSE FALSE 1960.947828 1770.129432 1841.405298 1991.624944 1557.800075 1819.783719 1603.872207 3480.80847 2083.218824 2181.666743 0.898830142 0.811365639 0.844036012 0.912891462 0.714041262 0.834125434 0.735159122 1.59548129 0.954874905 1 11.09121503 -4.253169904 24.88604683 0.897504319 1.59548166 0.843609919 0.093992333 340.7294461 1025362 0.015266181 0.230714921 5.58E-05 4.253169904 0.697977341 IACKS(ph)PPPESVDTPTSTK ddPTM_HeLa_Curcumin_4h_R1 2 IACKSPPPESVDTPTSTK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 IACKS(1)PPPESVDTPTSTK;IACKS(0.996)PPPES(0.001)VDT(0.003)PTSTK ; 99.603 0.00067535 89556000 7390.9 4270 5417.2 9299.4 6401.4 9097.1 7239.2 3759.8 9644.3 6705.4 TRUE FALSE FALSE 6805.902466 4639.079773 5617.966197 9260.921547 6325.067486 7210.258915 7442.312469 4906.145712 8586.344419 6938.412151 0.980902016 0.668608274 0.80969047 1.334732118 0.911601581 1.039179968 1.072624731 0.707099204 1.237508558 1 12.76038983 -8.213010085 0.006041663 1.949809795 1.86E-05 0.033445814 0.198974084 35529.71103 105.5373009 17227.0996 16828.0128 6.12E-09 8.213010085 -1.949791187 IACRS(ph)PQPDPVGT(ph)PTIFKPQSK ddPTM_HeLa_Curcumin_4h_R1 1 IACRSPQPDPVGTPTIFKPQSK 22 2 P46013;P46013-2 P46013 MKI67 Antigen KI-67 2 0 IACRS(0.999)PQPDPVGT(0.895)PT(0.048)IFKPQS(0.058)K 44.089 0.017693 20623000 1254.1 792.65 1141.7 1621.8 1345 2802.5 2461.8 791.82 1766.8 1234.4 TRUE FALSE FALSE 1154.836662 861.163134 1184.012406 1615.089421 1328.961753 2221.229909 2530.871482 1033.242273 1572.98646 1277.295308 0.904126598 0.674208328 0.926968414 1.264460467 1.040449883 1.739010466 1.981430188 0.808929827 1.231497877 1 10.3188764 -5.618351835 1.786820139 0.935376571 1.537706137 0.306684919 0.327271929 0.250302189 1.601685643 0.044634292 0.112344572 2.41E-06 5.618351835 0.602329566 IADDKYNDTFWK ddPTM_HeLa_Curcumin_4h_R1 1 IADDKYNDTFWK 12 1 P14625 P14625 HSP90B1 Endoplasmin 0 0 90.697 0.012507 55544000 2229.3 1947.2 2206.7 2494.3 2544.7 2061.8 1764.1 1616.4 2375.3 1871.8 FALSE FALSE TRUE 2052.848553 2115.507291 2288.482243 2483.979248 2514.356114 1634.159439 1813.595898 2109.232919 2114.735533 1936.844911 1.059893098 1.09224403 1.181551621 1.282487428 1.298171114 0.843722401 0.936366091 1.089004549 1.091845569 1 10.91949272 -3.876027064 19.48607801 1.05976212 8.708481522 0 0.137416805 5154.060952 801695.9973 0.019785429 18317.39974 0.000133037 3.876027064 7.648719403 IADGYEQAAR ddPTM_HeLa_Curcumin_4h_R1 1 IADGYEQAAR 10 0 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 0 146.79 1.11E-05 5086400 1935.7 1692.6 1528.6 1527.4 1537.6 2069.9 1629.7 1328.7 1849 1453.3 FALSE FALSE TRUE 1782.487302 1838.900802 1585.251261 1521.080024 1519.265124 1640.579407 1675.424996 1733.814513 1646.169326 1503.802067 1.185320423 1.222834336 1.054162177 1.011489515 1.010282641 1.090954351 1.11412601 1.152953937 1.094671541 1 10.55439897 -9.613467718 1.456319259 1.000671433 1.11312401 0.026382381 0.071879505 0.491309159 1.888485188 0.052618112 0.012408738 2.44E-10 9.613467718 0.112452577 SLS(ph)RPSSLIEQEK ddPTM_HeLa_Curcumin_4h_R1 1 SLSRPSSLIEQEK 13 1 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 S(0.12)LS(0.36)RPS(0.219)S(0.301)LIEQEK 65.298 0.01868 12325000 2238.2 1890.1 2068.6 2652.5 2016.2 2810.8 2631 9416.4 2280.3 2044.8 TRUE FALSE FALSE 2061.044108 2053.471822 2145.264136 2641.524658 1992.158132 2227.808396 2704.818779 12287.41701 2030.156795 2115.856648 0.974094398 0.970515571 1.01389862 1.248442167 0.941537383 1.052910838 1.278356349 5.807301277 0.95949638 1 11.04702617 -4.260066583 4.634838842 1.010802369 6.106914117 0.996627413 0.083162084 0.007507316 0.428655893 0.012054368 0.12387756 5.49E-05 4.260066583 5.096111748 up IADREDEYK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 IADREDEYKK 10 2 O75533;B4DGZ4;A0A494C1M2;O75533-2 O75533 SF3B1 Splicing factor 3B subunit 1 0 1 IADREDEYK(1)K 95.483 0.0034691 1994000 896.83 1161.6 993.8 818.41 1782.9 2509.2 1478.6 1274.1 2006.8 1030.9 FALSE TRUE FALSE 825.8449592 1262.003528 1030.631102 815.0236363 1761.640082 1988.763635 1520.085537 1662.567225 1786.659061 1066.723698 0.774188256 1.183065052 0.966165 0.764043808 1.651449279 1.864366226 1.425004 1.558573441 1.674903317 1 10.05897082 -5.755289406 24.9998682 0.913009163 1.627682231 0.439870602 0.284201803 44.52481157 180993.1981 0.023543832 0.046149399 1.76E-06 5.755289406 0.714673068 IAELEEEQSQGS(ph)TTNSDWMK ddPTM_HeLa_Curcumin_4h_R1 1 IAELEEEQSQGSTTNSDWMK 20 0 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 IAELEEEQS(0.006)QGS(0.39)T(0.273)T(0.193)NS(0.138)DWMK 73.138 0.0031439 4402900 1420.9 1599.5 1259.5 1180.1 1371.2 1769.1 1616.8 1173.6 1443 1320.1 TRUE FALSE FALSE 1308.434266 1737.753653 1306.178178 1175.217059 1354.849336 1402.168718 1662.163057 1531.425237 1284.70651 1365.973377 0.957876843 1.272172417 0.956225209 0.860351365 0.991856327 1.026497838 1.216834153 1.121123781 0.940506259 1 10.41571365 -4.870068655 5.196177506 0.992422618 1.167686145 0.301326128 0.102873055 0.173852029 7.180897741 0.014123021 0.044570534 1.35E-05 4.870068655 0.175263527 IAELEEEQSQGSTT(ph)NSDWMK ddPTM_HeLa_Curcumin_4h_R1 1 IAELEEEQSQGSTTNSDWMK 20 0 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 IAELEEEQSQGS(0.008)T(0.153)T(0.499)NS(0.34)DWMK 93.407 0.00089334 4214700 3276 2859.3 2995.8 3289.7 3308.8 4042.2 2720.4 2504.4 3770.1 3060.3 TRUE FALSE FALSE 3016.701143 3106.445151 3106.826983 3276.088093 3269.344721 3203.802155 2796.727102 3267.980031 3356.529462 3166.645197 0.952648925 0.98098933 0.98110991 1.034561149 1.032431648 1.011733856 0.883182968 1.032000691 1.059963859 1 11.62873952 -6.497696012 24.45311805 0.977446373 0.996237521 0 0.05002445 1764.777634 1713647.079 0.006830644 0.010405415 3.18E-07 6.497696012 0.018791148 IAEPS(ph)VCGR ddPTM_HeLa_Curcumin_4h_R1 1 IAEPSVCGR 9 0 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IU45 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 0 IAEPS(1)VCGR 90.149 0.019241 15811000 2938.1 2378.9 2640.9 2566.3 2821.4 3466.7 2196.8 1733.6 2828.4 2539.9 TRUE FALSE FALSE 2705.546285 2584.521516 2738.774077 2555.681331 2787.756648 2747.667342 2258.436296 2262.166659 2518.131596 2628.161336 1.02944452 0.983395304 1.0420875 0.972421782 1.060725082 1.045471336 0.859321787 0.860741169 0.958134328 1 11.35983813 -4.754982276 25 1.016088109 0.860031392 0.77992646 0.032100227 37.87446735 146634.5085 0.003539609 0.012628079 1.76E-05 4.754982276 -0.156056718 IAETDFEKR ddPTM_HeLa_Curcumin_4h_R1 2 IAETDFEKR 9 1 K7EJL5;K7EN19;A0A6I8PUD4;A0A6I8PS32;A0A6I8PIK4;A0A6I8PR89;A0A6I8PRZ0;K7ER44;A0A6I8PLE7;A0A6I8PU89;A0A6I8PUC2;K7EIH8;K7EPP7;K7EK03;K7ESP1;K7EJV7;A0A6I8PU73;Q99615-2;Q99615 K7EJL5 DNAJC7 DnaJ homolog subfamily C member 7 0 0 ; ; 114.89 0.011091 7557900 4513.7 3984.9 3885.5 4383.6 4160.3 5219.1 3751.1 3749.1 5484 4536.7 FALSE FALSE TRUE 4156.435882 4329.337 4029.500048 4365.461825 4110.69114 4136.599829 3856.34577 4892.183331 4882.41892 4694.349987 0.885412441 0.92224419 0.858372311 0.929939573 0.875667803 0.881186925 0.821486634 1.042142862 1.040062827 1 12.19670969 -9.271487187 0.785068893 1.00683878 0.896771619 0.388402825 0.057302925 0.664319945 0.662492642 0.046762633 0.010030048 5.35E-10 9.271487187 -0.110067161 IAGPGLGS(ph)GVR ddPTM_HeLa_Curcumin_4h_R1 1 IAGPGLGSGVR 11 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 1 0 IAGPGLGS(1)GVR 96.756 0.01307 13589000 1992.3 1410.2 1691.9 1530.3 1635.8 2955.5 2091.3 1335.4 1821.4 1675.9 TRUE FALSE FALSE 1834.607353 1532.091404 1754.603302 1523.968024 1616.294153 2342.495985 2149.97625 1742.557313 1621.596977 1734.1374 1.057936558 0.88348905 1.011801777 0.878804657 0.932045035 1.350813369 1.239795791 1.004855389 0.935102937 1 10.7600025 -5.276170792 24.95726573 0.998757212 1.202618955 0.518566866 0.101146331 501.6098495 849803.2476 0.014416153 0.032355287 5.29E-06 5.276170792 0.203861743 IAGS(ph)S(ph)PRLDY(ph)S(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 IAGSSPRLDYSR 12 1 P42695;E9PKK4;G3V1A9 P42695 NCAPD3 Condensin-2 complex subunit D3 4 0 IAGS(1)S(1)PRLDY(1)S(1)R 53.597 0.0095737 0 0 210.67 241.82 267.36 168.36 356.65 56.579 185.75 295.25 215.08 TRUE FALSE FALSE 0 228.8793761 250.7820619 266.2537352 166.352417 282.6767697 58.16645447 242.3843199 262.8618137 222.554014 0 1.028421694 1.12683684 1.196355574 0.747469857 1.270149051 0.26135882 1.08910334 1.181114683 1 7.798011711 IAHFLDR ddPTM_HeLa_Curcumin_4h_R1 1 IAHFLDR 7 0 P60228;H0YBR5;E5RIP5;E5RJ25;E5RII3;E5RHS5 P60228 EIF3E Eukaryotic translation initiation factor 3 subunit E 0 0 98.418 0.016508 9123600 9704 5833.8 8540.7 6451.6 9041.8 13383 9277.3 9958.5 8662.5 8997.1 FALSE FALSE TRUE 8935.91816 6338.047677 8857.225855 6424.904989 8933.98244 10607.21494 9537.596069 12994.80081 7712.245423 9309.748555 0.959845275 0.68079687 0.951392597 0.690126586 0.959637351 1.139366426 1.024474078 1.395827259 0.828405341 1 13.18452649 -3.544230405 0.977322237 0.936755221 2.638229728 0.56292524 0.131554308 4.193050804 1.12668919 0.020360385 10.55301032 0.000285607 3.544230405 1.701474507 IAILTCPFEPPKPK ddPTM_HeLa_Curcumin_4h_R1 2 IAILTCPFEPPKPK 14 1 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 0 ; ; 160.22 0.00020598 1476910 1885.83 1624.52 1682.93 1635.9 1383.24 2073.47 1473.77 1108.33 1853.02 1623.91 FALSE FALSE TRUE 1736.564566 1764.93627 1745.300866 1629.131079 1366.745766 1643.408949 1515.12002 1446.254715 1649.748342 1680.340752 1.033459769 1.050344264 1.038658894 0.969524234 0.813374171 0.978021242 0.90167427 0.860691329 0.981793925 1 10.71453811 -5.98480732 10.83333829 1.020178835 0.895190039 0.682104542 0.042539058 0.160605106 110.455403 0.005851901 0.010536849 1.04E-06 5.98480732 -0.124988795 IALEARPLLSQEDS(ph)EEEENELEAINR ddPTM_HeLa_Curcumin_4h_R1 2 IALEARPLLSQEDSEEEENELEAINR 26 1 Q9H1H9-3;Q9H1H9-4;Q9H1H9-2 Q9H1H9-3 KIF13A Kinesin-like protein KIF13A 1 0 IALEARPLLS(0.019)QEDS(0.981)EEEENELEAINR;IALEARPLLS(0.008)QEDS(0.992)EEEENELEAINR ; 67.758 0.00031427 13548400 867.36 603.53 586.9 763.15 568.27 795.24 677.99 503.38 808.27 562.53 TRUE FALSE FALSE 798.7075408 655.6964439 608.6510303 759.9922875 561.4937514 630.2982598 697.0125747 656.8582447 719.6048032 582.0778756 1.372166121 1.126475462 1.045652233 1.305653967 0.964636821 1.082841809 1.19745588 1.128471416 1.236268948 1 9.185068373 -5.762751961 24.99986432 1.173009633 1.100036845 0.114374278 0.117688193 98.43989378 1874989.266 0.022894571 0.043219978 1.73E-06 5.762751961 -0.072972788 IALEARPLLSQEDS(ph)EEEENELEAINRK ddPTM_HeLa_Curcumin_4h_R1 3 IALEARPLLSQEDSEEEENELEAINRK 27 2 Q9H1H9-3;Q9H1H9-4;Q9H1H9-2 Q9H1H9-3 KIF13A Kinesin-like protein KIF13A 1 0 IALEARPLLS(0.011)QEDS(0.989)EEEENELEAINRK;IALEARPLLS(0.022)QEDS(0.978)EEEENELEAINRK;IALEARPLLS(0.166)QEDS(0.834)EEEENELEAINRK ;; 73.672 7.91E-05 60539000 4763.03 3359.15 3615.61 4190.5 3283.08 4717.03 3204.28 3016.68 5690.6 4197.45 TRUE FALSE FALSE 4386.03115 3649.499958 3749.607687 4173.160821 3243.931415 3738.664806 3294.183473 3936.451845 5066.355417 4343.311075 1.009835831 0.840257558 0.863306271 0.96082476 0.746879825 0.860786792 0.758449813 0.9063251 1.166473073 1 12.08457957 -7.2616002 24.99360274 1.0046447 0.846182221 0.579996697 0.078164309 6.603289841 1026211.84 0.009351597 0.011060436 5.48E-08 7.2616002 -0.15846248 IALESEGRPEEQMESDNCSGGDDDWT(ph)HLSSK ddPTM_HeLa_Curcumin_4h_R1 1 IALESEGRPEEQMESDNCSGGDDDWTHLSSK 31 1 Q13501;Q13501-2 Q13501 SQSTM1 Sequestosome-1 1 0 IALESEGRPEEQMESDNCSGGDDDWT(0.792)HLS(0.17)S(0.038)K 80.813 1.19E-06 3089900 1013.1 901.95 931.81 1004.5 1510.9 1394.8 771.86 897.09 1215.6 942.63 TRUE FALSE FALSE 932.912066 979.910539 966.3436983 1000.343645 1492.883504 1105.502757 793.5163142 1170.608611 1082.251721 975.3863223 0.956453914 1.004638384 0.990729187 1.025587116 1.530556119 1.133399897 0.813540539 1.200148684 1.109562126 1 9.929829932 -5.980183024 24.99990447 0.983113593 1.158501168 0.160505759 0.166521394 295.7887661 373147.3608 0.02385618 0.043239478 1.05E-06 5.980183024 0.175387576 IALLEEENSRPHTNET(ph)SL ddPTM_HeLa_Curcumin_4h_R1 2 IALLEEENSRPHTNETSL 18 1 D6REY2;P23508;P23508-2 D6REY2 MCC Colorectal mutant cancer protein 1 0 IALLEEENSRPHTNET(0.5)S(0.5)L;IALLEEENSRPHT(0.017)NET(0.668)S(0.315)L ; 81.448 0.0048279 14919100 3827.5 3533.6 4030.8 3726.9 3339.6 5184.4 3524.7 3071.87 4944.4 4333.7 TRUE FALSE FALSE 3524.549336 3839.028639 4180.184994 3711.479075 3299.777451 4109.097 3623.593596 4008.469022 4402.01169 4484.295752 0.785976111 0.856105139 0.932183162 0.827661528 0.735851878 0.916330507 0.808063026 0.893890422 0.981650617 1 12.13066572 -9.429412188 1.091240187 1.002427667 0.83958449 0.508929514 0.057225105 0.332777736 0.691727846 0.04238273 0.010016549 3.72E-10 9.429412188 -0.162843177 IALLEEENSRPHTNETS(ph)L ddPTM_HeLa_Curcumin_4h_R1 1 IALLEEENSRPHTNETSL 18 1 D6REY2;P23508;P23508-2 D6REY2 MCC Colorectal mutant cancer protein 1 0 IALLEEENSRPHT(0.004)NET(0.447)S(0.55)L 71.98 0.0055071 8171200 1621.5 1354.9 1232.5 1359.3 1387.6 1793.7 1409.2 686.5 1877.8 1870.1 TRUE FALSE FALSE 1493.156564 1472.011519 1278.177534 1353.675577 1371.053776 1421.666401 1448.738359 895.8106897 1671.810038 1935.085836 0.77162291 0.760695723 0.660527564 0.69954291 0.708523493 0.734678728 0.748668784 0.462930725 0.863946191 1 10.91818185 -13.52287875 0.114051052 2.076264644 0.514532673 0.597947426 0.082720293 33.16166547 0.275972598 8.176013943 0.382964211 3.00E-14 13.52287875 -1.561731971 IALTDNALIAR ddPTM_HeLa_Curcumin_4h_R1 2 IALTDNALIAR 11 0 P18124;A8MUD9 P18124 RPL7 60S ribosomal protein L7 0 0 ; ; 121.9 0.0018552 13059700 4002.5 3474.4 3606.4 3703.9 3582.5 5156.5 3891.9 3636.9 4397.3 3375.9 FALSE FALSE TRUE 3685.697902 3774.711654 3740.056357 3688.574243 3539.781027 4086.983774 4001.096239 4745.774068 3914.927192 3493.212274 1.055102757 1.080584676 1.070663923 1.055926166 1.013331212 1.169978648 1.14539167 1.358570192 1.120724103 1 11.7703386 -1 0.567588119 1.030613412 17.1927951 0.782385705 0.045815761 32.13754493 0.254396272 0.006845733 639.8576677 0.1 1 16.16218168 IANLQTDLSDGLR ddPTM_HeLa_Curcumin_4h_R1 1 IANLQTDLSDGLR 13 0 P21333-2;P21333;F8WE98;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 206.1 1.02E-19 2124900 1107.7 787.83 1060.9 1307.8 1112.6 681.59 661.87 742.3 1082.7 1109 FALSE FALSE TRUE 1020.024376 855.9265147 1100.217887 1302.38867 1099.332972 540.2205509 680.4402909 968.6238529 963.9305188 1147.537667 0.888880954 0.745880975 0.958764072 1.134941978 0.957992929 0.470764983 0.592956824 0.84408894 0.839999022 1 10.16432579 -5.279834497 24.38135024 0.946772784 0.631638914 0.524154555 0.128892143 310.5002355 411544.5334 0.018289523 0.040974461 5.25E-06 5.279834497 -0.31513387 IANPVEGSSGR ddPTM_HeLa_Curcumin_4h_R1 1 IANPVEGSSGR 11 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 0 0 122.94 0.0017192 4532600 1974.5 1523.5 2021 1834.7 1607.8 1932.9 1607.4 1408.6 2256.1 1546.9 FALSE FALSE TRUE 1818.216242 1655.184551 2095.900038 1827.108498 1588.628035 1531.994752 1652.499318 1838.075656 2008.611474 1600.65466 1.135920375 1.034067243 1.309401766 1.141475762 0.992486434 0.957105108 1.032389659 1.148327432 1.254868726 1 10.64444637 -4.239112841 21.69602312 1.071364687 1.148327924 0 0.112560423 2510.62891 2439487.458 0.014371544 0.738579134 5.77E-05 4.239112841 0.076963237 IAQLEEELEEEQGNTELINDR ddPTM_HeLa_Curcumin_4h_R1 2 IAQLEEELEEEQGNTELINDR 21 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ; ; 214.52 1.33E-22 39608000 4116.6 3261.84 3652.49 4000.79 3845.5 4422.2 3106.53 3599.93 4431.7 3764.95 FALSE FALSE TRUE 3790.766766 3543.778915 3787.854492 3984.235791 3799.644924 3504.985872 3193.690871 4697.532085 3945.553598 3895.781732 0.97304393 0.909645139 0.972296384 1.022705086 0.975322845 0.899687434 0.819781777 1.205799608 1.012775835 1 11.92769713 -8.524092235 1.071189949 0.996385536 0.965231653 0.01329231 0.095004703 1.829793575 4.267331929 0.029852626 0.017570169 2.99E-09 8.524092235 -0.031153883 IAQLEEQLDNETKER ddPTM_HeLa_Curcumin_4h_R1 4 IAQLEEQLDNETKER 15 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ;;; ;;; 230.67 5.55E-21 47764400 11339.9 9124.5 8282 10094.1 7491.1 11337.1 8936.3 9198.4 12909 11613.5 FALSE FALSE TRUE 10442.33495 9913.181122 8588.938206 10052.33329 7401.773525 8985.657665 9187.028527 12002.94982 11492.915 12017.06826 0.868958611 0.82492509 0.714728253 0.836504634 0.615938377 0.747741252 0.764498323 0.998825134 0.956382601 1 13.55279735 -7.962380547 0.725503786 0.982004918 0.772266843 0.390541367 0.094021032 0.387691708 0.451726737 0.032744972 0.02386635 1.09E-08 7.962380547 -0.209738075 IAQLSES(ph)PVILT(ph)PNAK ddPTM_HeLa_Curcumin_4h_R1 1 IAQLSESPVILTPNAK 16 0 Q6P4F7-3;Q6P4F7;H3BQ41;H3BR51;Q6P4F7-2 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 2 0 IAQLS(0.107)ES(0.987)PVILT(0.906)PNAK 121.03 0.0039407 6464700 3600 3232.5 2899.6 3358.5 3743 5092.8 4095.5 1080.2 3449.8 2747.3 TRUE FALSE FALSE 3315.056201 3511.902896 3007.061727 3344.603417 3698.36717 4036.495872 4210.408708 1409.548007 3071.365571 2842.768471 1.166136545 1.23538126 1.0577934 1.176530362 1.300973754 1.419917209 1.481094486 0.495836373 1.080413549 1 11.47308089 -8.890207602 0.580905018 0.986160641 1.194943926 0.026393933 0.25665251 2.139070168 1.259252 0.227395067 0.060600004 1.29E-09 8.890207602 0.208783285 SVS(ph)SNVASVSPIPAGSK ddPTM_HeLa_Curcumin_4h_R1 2 SVSSNVASVSPIPAGSK 17 0 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 0 S(0.001)VS(0.99)S(0.009)NVAS(0.001)VSPIPAGSK;S(0.007)VS(0.496)S(0.496)NVASVSPIPAGSK ; 171.52 5.44E-05 29602000 2873.1 1838.5 3366.7 3016.1 3001.2 3164.1 5345 31485 0 3012 TRUE FALSE FALSE 2645.691103 1997.411748 3491.472864 3003.620177 2965.41265 2507.829993 5494.966315 41084.63156 0 3116.666776 0.848884816 0.640880752 1.120258634 0.963728365 0.951469266 0.804651307 1.763090734 13.18223426 0 1 11.6057882 -4.260061357 4.337345304 0.925518013 14.09687505 0.99266495 0.317561596 0.005272334 0.233968984 0.019602553 0.213476654 5.49E-05 4.260061357 13.17135704 up VTTEIQLPSQS(ph)PVEEQSPASLSSLR ddPTM_HeLa_Curcumin_4h_R1 3 VTTEIQLPSQSPVEEQSPASLSSLR 25 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 VTT(0.001)EIQLPS(0.374)QS(0.625)PVEEQSPASLSSLR;VTTEIQLPS(0.005)QS(0.995)PVEEQSPASLSSLR;VTTEIQLPS(0.043)QS(0.858)PVEEQS(0.096)PAS(0.002)LSSLR ;; 132.7 3.22E-08 160810000 12462.8 9727.6 10243.6 10836.3 10463.1 14541.2 12451.5 32020.5 13920.1 10762.8 TRUE FALSE FALSE 11476.35623 10568.4104 10623.23683 10791.46226 10338.33437 11525.19121 12800.85558 41783.40305 12393.09986 11136.8065 1.030488967 0.94896238 0.953885374 0.96899073 0.928303313 1.034873975 1.149418873 3.751829849 1.11280553 1 13.44304798 -4.260022002 4.666116798 0.999722428 3.920649652 0.996198531 0.050810768 0.006658807 0.390274784 0.006192368 0.063320245 5.50E-05 4.260022002 2.920927224 up IAS(ph)LEVENQSLR ddPTM_HeLa_Curcumin_4h_R1 2 IASLEVENQSLR 12 0 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;E9PL12;E9PPR1;E9PIZ1;E9PMW7;E9PN91;H0YCK7 P29692;E9PMW7 EEF1D Elongation factor 1-delta 1 0 IAS(1)LEVENQSLR;IAS(1)LEVENQSLR ; 143.58 0.00097616 9479900 526.28 578.05 626 552.07 782.15 985.69 610.83 1107.28 754.77 733.21 TRUE FALSE FALSE 484.6243827 628.0140663 649.2001107 549.7856806 772.8233721 781.246783 627.9682458 1444.884575 671.9736193 758.6889929 0.638765538 0.827762195 0.85568674 0.724652243 1.018630004 1.029732592 0.827701801 1.904449107 0.885703662 1 9.567364797 -2.413046742 1.428397828 0.8373799 200 0.841369663 0.132729467 90.37013023 1.248887176 0.023596719 58011.56072 0.003863254 2.413046742 199.1626201 IASDEEIQGTKDAVIQDLER ddPTM_HeLa_Curcumin_4h_R1 1 IASDEEIQGTKDAVIQDLER 20 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;Q8WX93-4;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 0 0 100.02 0.00048037 1091300 418.13 403.88 249.61 298.13 347.94 288.99 296.93 197.99 307.3 271.65 FALSE FALSE TRUE 385.0345693 438.7895875 258.8607662 296.8964171 343.7910427 229.0502164 305.2610567 258.3562396 273.5899588 281.0898173 1.369791951 1.561029822 0.920918334 1.056233271 1.223064735 0.814864866 1.08599116 0.919123439 0.973318641 1 8.134887382 IAT(ph)GSFLKR ddPTM_HeLa_Curcumin_4h_R1 1 IATGSFLKR 9 1 E9PBS1;P22234;P22234-2;D6RF62 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 0 IAT(0.762)GS(0.238)FLKR 73.841 0.0092127 0 2036.8 2109.3 2173.4 2276.1 1869.3 2650.3 2038.7 1948.7 2435.4 2590.4 TRUE FALSE FALSE 1875.585131 2291.618493 2253.948116 2266.682101 1847.009818 2100.597905 2095.900435 2542.849659 2168.242713 2680.416207 0.699736528 0.854948753 0.840894824 0.845645574 0.689075754 0.783683481 0.781930966 0.948677169 0.808920162 1 11.38824132 -9.504428432 1.232629137 1.000831862 0.792663495 0 0.092669696 0.304995249 0.824068387 0.053824959 0.012811206 3.13E-10 9.504428432 -0.208168367 ICDDELILIK ddPTM_HeLa_Curcumin_4h_R1 1 ICDDELILIK 10 0 P17987;E7EQR6;F5H282;E7ERF2;F5GZ03 P17987 TCP1 T-complex protein 1 subunit alpha 0 0 141.88 2.03E-05 389340 259.25 204.58 221.06 145.29 393.34 229.25 184.81 313.82 269.72 205.11 FALSE FALSE TRUE 238.7300889 222.2629836 229.2526781 144.6888285 388.6496774 181.7009658 189.9952712 409.5022734 240.1323908 212.2375572 1.124824899 1.047236816 1.080170169 0.681730559 1.831201237 0.856120699 0.895200989 1.929452443 1.131432127 1 7.729536166 -4.254415807 24.66508728 1.065304816 1.929452931 0.446694476 0.286207534 445.4656791 1564319.272 0.035453 0.472451711 5.57E-05 4.254415807 0.864148115 ICDQWDALGSLTHSR ddPTM_HeLa_Curcumin_4h_R1 1 ICDQWDALGSLTHSR 15 0 O43707;O43707-2;F5GXS2;O43707-3 O43707 ACTN4 Alpha-actinin-4 0 0 147.53 0.00037332 18963000 2305 1400.5 1607.5 1301.3 2618 5424.6 2713.7 2190.8 1465.5 1329 FALSE FALSE TRUE 2122.556818 1521.552979 1667.075364 1295.915565 2586.78206 4299.476812 2789.839118 2858.764835 1304.738317 1375.182651 1.543472655 1.106437009 1.212257414 0.942358867 1.881046171 3.126476915 2.028704417 2.078825553 0.948774561 1 10.42540753 -5.55097078 5.636735146 1.230462631 2.39613885 0.751260504 0.332107676 0.069359356 6.354561999 0.049542432 0.102253376 2.81E-06 5.55097078 1.165676219 up ICRDPQT(ph)PVLQTK ddPTM_HeLa_Curcumin_4h_R1 1 ICRDPQTPVLQTK 13 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 0 ICRDPQT(0.998)PVLQT(0.002)K 147.56 0.0063394 42585000 4010.3 2777.1 2819.4 3595.2 3020 5726.4 4618.9 1431.1 4053.2 3253.9 TRUE FALSE FALSE 3692.880523 3017.140149 2923.889444 3580.324015 2983.988472 4538.68009 4748.493903 1867.435802 3608.574101 3366.972783 1.096795478 0.896098764 0.868403053 1.063365892 0.886252627 1.348000231 1.4103155 0.554633471 1.071756243 1 11.71723634 -5.292098586 24.93056816 1.013702846 1.134916582 0.039516266 0.228493507 1486.374647 1208645.162 0.030506807 0.068222205 5.10E-06 5.292098586 0.121213736 ICT(ph)LPEK ddPTM_HeLa_Curcumin_4h_R1 1 ICTLPEK 7 0 G3V120;E7ER68;Q658Y4 G3V120 FAM91A1 Protein FAM91A1 1 0 ICT(1)LPEK 132.72 0.017811 98497000 6417.4 5489.3 5523.6 6398.2 6461.2 7960.4 6477.8 6886.9 7474.2 6129.3 TRUE FALSE FALSE 5909.456018 5963.770632 5728.309475 6371.725944 6384.15441 6309.323308 6659.549634 8986.684107 6654.29896 6342.292719 0.931753907 0.940317784 0.903192225 1.004640786 1.006600404 0.994801657 1.050022433 1.416945654 1.049194551 1 12.63078875 -3.722228319 1.331151958 0.964760258 2.490633167 0.904459116 0.042336185 0.88977791 0.500852177 0.005683716 2.618214432 0.000189571 3.722228319 1.525872909 ICTLPSPPS(ph)PLASLAPVADSSTR ddPTM_HeLa_Curcumin_4h_R1 2 ICTLPSPPSPLASLAPVADSSTR 23 0 Q9UER7-3;Q9UER7;Q9UER7-2 Q9UER7-3 DAXX Death domain-associated protein 6 1 0 ICTLPS(0.007)PPS(0.992)PLAS(0.001)LAPVADSSTR;ICTLPS(0.002)PPS(0.994)PLAS(0.001)LAPVADS(0.001)S(0.001)T(0.001)R ; 78.45 0.00028679 14779800 3974.4 3215 3907.1 3809 4133.8 5275.2 3477.4 2029.08 4203.5 3710.7 TRUE FALSE FALSE 3659.822046 3492.890274 4051.900563 3793.239367 4084.507135 4181.064056 3574.966485 2647.737151 3742.386567 3839.646549 0.953166392 0.909690574 1.055279571 0.987913684 1.063771647 1.088918994 0.931066555 0.689578355 0.974669548 1 11.9067578 -4.296565919 3.619171866 0.991345985 0.665944268 0.758630497 0.052756749 0.09596946 2.247527556 0.007704484 0.079118096 5.05E-05 4.296565919 -0.325401717 IDAGTMAEPSAS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 3 IDAGTMAEPSASPSK 15 0 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 0 IDAGTMAEPS(0.021)AS(0.753)PS(0.227)K;IDAGTMAEPS(0.009)AS(0.889)PS(0.102)K;IDAGTMAEPS(0.028)AS(0.958)PS(0.014)K ;; 146.27 0.00055951 48441000 13363.3 10892.9 11214.6 12025.8 12036.4 13957.5 11326.6 5023.8 11212.9 9712 TRUE FALSE FALSE 12305.5807 11834.43374 11630.22294 11976.04043 11892.87379 11062.55717 11644.39391 6555.533493 9982.872923 10049.49128 1.224497874 1.177615206 1.157294695 1.191706137 1.183430431 1.100807679 1.158704813 0.65232491 0.993370973 1 13.29483485 -4.25929295 24.94117738 1.129341549 0.65232474 0.78741722 0.074749598 76.16505573 884961.5899 0.012447507 0.109744178 5.50E-05 4.25929295 -0.477016809 IDASKNEEDEGHSNS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 IDASKNEEDEGHSNSSPR 18 1 Q14103-3;D6RAF8;Q14103;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 0 IDASKNEEDEGHS(0.007)NS(0.496)S(0.496)PR 55.707 0.013779 3260800000 4783.4 4011.9 3853 3348.6 4128.2 5091.5 3954.1 3643.4 4432 3674.3 TRUE FALSE FALSE 4404.788843 4358.670759 3995.795569 3334.74438 4078.973911 4035.465507 4065.041404 4754.255888 3945.820688 3801.981652 1.158550789 1.146420777 1.050977079 0.877106911 1.072854707 1.061411095 1.069190169 1.250467867 1.037832649 1 11.89253585 -4.261427808 6.211623338 1.064790567 1.25488233 0.377652748 0.07474722 0.1280939 26.01765147 0.012034254 0.102104755 5.48E-05 4.261427808 0.190091763 IDASKNEEDEGHSNSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 5 IDASKNEEDEGHSNSSPR 18 1 Q14103-3;D6RAF8;Q14103;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 0 IDASKNEEDEGHS(0.045)NS(0.336)S(0.618)PR;IDASKNEEDEGHS(0.005)NS(0.263)S(0.732)PR;IDASKNEEDEGHSNS(0.242)S(0.757)PR;IDASKNEEDEGHS(0.026)NS(0.071)S(0.904)PR;IDASKNEEDEGHS(0.15)NS(0.231)S(0.619)PR ;;;; 143.23 0.00010568 3878835100 17341.86 14563.14 14377.43 15243.94 17023.44 19141.61 16257.9 14790.93 16776.3 14063.88 TRUE FALSE FALSE 15969.23348 15821.91293 14910.2702 15180.86462 16820.4466 15171.42432 16714.05292 19300.61647 14935.98186 14552.59878 1.097345823 1.087222507 1.024577838 1.043172071 1.155837995 1.042523369 1.14852702 1.326265965 1.026344647 1 13.82898919 -1 0.78441854 1.050709401 63.3125224 0.783809612 0.042678868 165.0943311 0.578873551 0.007815532 18251.2119 0.1 1 62.261813 IDASKNEEDEGHSNSSPR ddPTM_HeLa_Curcumin_4h_R1 2 IDASKNEEDEGHSNSSPR 18 1 Q14103-3;D6RAF8;Q14103;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 0 ; ; 85.576 0.0026538 5238600 7979.2 7555.1 6247.8 6624.1 10651.5 14054.2 8888.5 8123.3 10028.6 7068.8 FALSE FALSE TRUE 7347.6379 8208.129179 6479.348964 6596.691229 10524.48782 11139.2005 9137.887388 10600.05677 8928.48767 7314.440274 1.004538642 1.122181448 0.885829773 0.901872321 1.438864414 1.522905387 1.249294142 1.449195889 1.22066588 1 12.83653175 -5.755825571 24.99977849 0.996236607 1.410927154 0.740214149 0.113277277 37.57638415 167335.8366 0.012436922 0.024330745 1.75E-06 5.755825571 0.414690546 IDASKNEEDEGK ddPTM_HeLa_Curcumin_4h_R1 1 IDASKNEEDEGK 12 1 Q14103-4;Q14103-2;D6RBQ9 Q14103-4 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 0 105.2 0.0023931 2532100 2347.6 2148.5 2153.1 2051.2 2824.8 3230.6 2085.7 2312.7 2137.9 1836.2 FALSE FALSE TRUE 2161.784983 2334.206766 2232.89578 2042.712678 2791.116105 2560.537144 2144.219129 3017.831584 1903.377719 1900.007813 1.137776891 1.228524825 1.175203473 1.075107515 1.469002435 1.347645586 1.128531743 1.588325881 1.001773627 1 10.89178964 -1.000000001 0.118840968 0.894313285 2.587152369 0.554743039 0.124469952 51.67557699 0.423336625 0.543117763 14.52445301 0.1 1.000000001 1.692839084 IDATSASVLASR ddPTM_HeLa_Curcumin_4h_R1 1 IDATSASVLASR 12 0 A0A499FI48;P13667 A0A499FI48 PDIA4 Protein disulfide-isomerase A4 0 0 93.096 0.0058735 0 1204.3 698.56 861.09 1023.4 918.36 458.83 367.72 309.87 1293.3 1064.4 FALSE FALSE TRUE 1108.978384 758.9404137 893.0027529 1019.165442 907.4091568 363.6634859 378.0372335 404.3479365 1151.428226 1101.387821 1.006891817 0.689076454 0.810797737 0.92534657 0.823877965 0.330186587 0.343237165 0.367125847 1.045433955 1 10.10510684 -5.24123745 0.643401815 0.99132696 0.167887896 0.792740621 0.124276267 0.414704796 0.228755875 0.024468146 0.199102849 5.74E-06 5.24123745 -0.823439064 down IDDDDDERENFEITDWDLQNEFNPNR ddPTM_HeLa_Curcumin_4h_R1 1 IDDDDDERENFEITDWDLQNEFNPNR 26 1 Q9UBB9;F6XM96;F6UKU9;F6SQZ1;F6UQ07 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 0 0 57.238 0.0049352 4777500 385.96 317.22 387.82 449.76 326.49 403.03 494.72 193.97 368.22 309.85 FALSE FALSE TRUE 355.4108587 344.6390833 402.1929504 447.8990123 322.59682 319.4370349 508.6005117 253.1105601 327.8271872 320.6172644 1.108520651 1.07492366 1.254433229 1.396989688 1.006174201 0.996318883 1.586316671 0.789447694 1.022487631 1 8.324708303 -7.997245437 0.749518704 1.016203193 1.176426098 0.066919448 0.210683693 1.039954142 1.285386452 0.068243544 0.049092891 1.01E-08 7.997245437 0.160222905 IDDRDS(ph)DEEGASDR ddPTM_HeLa_Curcumin_4h_R1 4 IDDRDSDEEGASDR 14 1 Q8TDD1-2;Q8TDD1 Q8TDD1-2 DDX54 ATP-dependent RNA helicase DDX54 1 0 IDDRDS(0.991)DEEGAS(0.009)DR;IDDRDS(0.997)DEEGAS(0.003)DR;IDDRDS(0.829)DEEGAS(0.171)DR;IDDRDS(1)DEEGASDR ;;; 222.51 2.17E-13 241407000 14894.3 12767.1 14204 14681.7 14594.1 17013.6 14219.4 10181.4 14635 12501.9 TRUE FALSE FALSE 13715.40044 13870.63123 14730.41274 14620.95102 14420.07489 13484.78758 14618.35809 13285.66199 13029.57711 12936.34009 1.060222624 1.072222215 1.138684715 1.130223147 1.114695098 1.042395877 1.13002271 1.027003147 1.007207372 1 13.65914189 -8.086116507 0.782591868 1.008461239 1.096935769 0.482774622 0.036279625 0.332537746 0.443641135 0.012534986 0.008600792 8.20E-09 8.086116507 0.088474531 IDEDGENTQIEDTEPMS(ph)PVLNSK ddPTM_HeLa_Curcumin_4h_R1 7 IDEDGENTQIEDTEPMSPVLNSK 23 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 IDEDGENTQIEDTEPMS(0.999)PVLNS(0.001)K;IDEDGENTQIEDTEPMS(0.997)PVLNS(0.003)K;IDEDGENTQIEDTEPMS(0.999)PVLNS(0.001)K;IDEDGENTQIEDTEPMS(1)PVLNSK;IDEDGENTQIEDT(0.001)EPMS(0.997)PVLNS(0.002)K;IDEDGENTQIEDTEPMS(1)PVLNSK;IDEDGENTQIEDTEPMS(1)PVLNSK ;;;;;; 221.42 9.87E-24 431230000 35995.9 29054 32675.3 32341.2 34516.8 37117.3 32923.5 28722.2 32182.3 29227 TRUE FALSE FALSE 33146.78653 31565.2983 33886.27536 32207.38068 34105.2097 29418.75358 33847.2448 37479.46656 28651.98221 30242.63607 1.096028351 1.043735018 1.120480215 1.06496605 1.127719476 0.972757583 1.119189634 1.239292318 0.947403597 1 14.88429628 -13.52281317 0.015997391 4.88E-07 1.923423728 0.395662546 0.063934597 3959.14492 5.114092857 384.9968947 244.8382442 3.00E-14 13.52281317 1.923423239 IDEMPEAAVK ddPTM_HeLa_Curcumin_4h_R1 2 IDEMPEAAVK 10 0 P51858 P51858 HDGF Hepatoma-derived growth factor 0 0 ; ; 159.37 7.44E-09 9209200 5155.1 4751 5285 5430.4 5420 6538.2 5071.9 4376.4 5534.5 4849.4 FALSE FALSE TRUE 4747.068395 5161.65527 5480.866749 5407.930444 5355.37004 5182.103619 5214.203864 5710.744214 4927.379197 5017.916289 0.946023832 1.028645153 1.092259502 1.077724325 1.067249777 1.032720221 1.039117347 1.138070841 0.981957233 1 12.29287269 -7.025213091 4.559297245 0.974739928 1.070496171 0.681345871 0.030133855 0.092973533 4.741284172 0.005488636 0.006956813 9.44E-08 7.025213091 0.095756243 IDENS(ph)DKEMEVEESPEK ddPTM_HeLa_Curcumin_4h_R1 2 IDENSDKEMEVEESPEK 17 1 Q8N3X1-2;Q8N3X1 Q8N3X1-2 FNBP4 Formin-binding protein 4 1 0 IDENS(1)DKEMEVEESPEK;IDENS(1)DKEMEVEESPEK ; 63.674 0.012381 46995000 4954.9 3766.4 4875.6 4042.1 5003.4 4402.8 4364.7 3622.2 3942.8 3666.4 TRUE FALSE FALSE 4562.714437 4091.950833 5056.294025 4025.374861 4943.737723 3489.60965 4487.161735 4726.592105 3510.284704 3793.807127 1.202674328 1.078586943 1.33277572 1.061038352 1.30310729 0.919817358 1.182759583 1.245870427 0.925267044 1 11.88943062 -9.354283675 0.951818043 0.994720363 1.1648632 0.305638005 0.118647204 0.697573486 1.073856596 0.08516487 0.019615416 4.42E-10 9.354283675 0.170142837 IDEPLEGSEDR ddPTM_HeLa_Curcumin_4h_R1 5 IDEPLEGSEDR 11 0 P61978-3;P61978;P61978-2;S4R359 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 0 ;;;; ;;;; 201.61 5.85E-08 288181000 10680.5 9508.1 10379.7 10772.6 11445.3 12461.6 11090.1 10110.7 8665.9 7988.5 FALSE FALSE TRUE 9835.127155 10329.9378 10764.38081 10728.02584 11308.82227 9876.923689 11401.25836 13193.40589 7715.272451 8266.09978 1.189814715 1.249674946 1.302232141 1.29783406 1.368096511 1.194871094 1.379279063 1.59608597 0.933363092 1 13.01299106 -1.000000001 0.058804469 0.48575172 2.894772661 0.806884174 0.079205751 102.3955663 0.455111543 3.918943581 21.37894035 0.1 1.000000001 2.409020941 IDFDSVSSIMAS(ph)SQ ddPTM_HeLa_Curcumin_4h_R1 1 IDFDSVSSIMASSQ 14 0 A0A087WVB9;K7ERF1;Q9UBQ5;K7EK53 A0A087WVB9 EIF3K Eukaryotic translation initiation factor 3 subunit K 1 0 IDFDSVSSIMAS(0.725)S(0.275)Q 133.98 0.0011217 3111100 1302 1104.1 1111.5 1188.5 1334.7 1997.5 1512 1262.7 1094.8 1298 TRUE FALSE FALSE 1198.945326 1199.533484 1152.693168 1183.582302 1318.784574 1583.195984 1554.422651 1647.691417 974.7031791 1343.105403 0.892666594 0.893104503 0.858229864 0.881228159 0.981892092 1.17875781 1.15733482 1.226777447 0.725708628 1 10.39135681 -5.31198069 3.439567471 0.931543999 1.188848073 0.743714513 0.077882863 0.077880029 1.86433151 0.008366863 0.020897061 4.88E-06 5.31198069 0.257304074 IDFDSVSSIMASS(ph)Q ddPTM_HeLa_Curcumin_4h_R1 2 IDFDSVSSIMASSQ 14 0 A0A087WVB9;K7ERF1;Q9UBQ5;K7EK53 A0A087WVB9 EIF3K Eukaryotic translation initiation factor 3 subunit K 1 0 IDFDSVSSIMAS(0.471)S(0.529)Q;IDFDSVSSIMAS(0.008)S(0.992)Q ; 175.21 0.00022119 17355500 8055.5 6926.8 6646.7 6816 7282.3 8883.2 7642.7 4980 7532.4 7310.5 TRUE FALSE FALSE 7417.898675 7525.521727 6893.032549 6787.797198 7195.463329 7040.724186 7857.133593 6498.379075 6706.114565 7564.539331 0.980614728 0.994842038 0.911229653 0.897317986 0.951209719 0.930753861 1.03867972 0.859058138 0.886519889 1 12.88503651 -6.774897197 24.97521896 0.990889786 0.93557766 0.003603934 0.054687111 215.3274229 399606.7988 0.006604028 0.00870688 1.68E-07 6.774897197 -0.055312126 IDFIPVSPAPS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 IDFIPVSPAPSPTR 14 0 Q96E09 Q96E09 FAM122A Protein FAM122A 1 0 IDFIPVSPAPS(0.915)PT(0.085)R 112.96 0.0037638 0 1099 856.09 871.89 959.93 673.14 1045 615.56 448.21 1066.5 834.41 TRUE FALSE FALSE 1012.01299 930.0866049 904.2030104 955.958064 665.1132451 828.2552204 632.8309569 584.8671657 949.5076183 863.4056854 1.172117589 1.077230114 1.047251629 1.107194544 0.770336884 0.959288588 0.732947405 0.677395546 1.099723611 1 9.753894783 -5.14478591 0.822597762 1.084773284 0.652490898 0.747378065 0.083552137 0.399477572 0.385860734 0.015621181 0.119360269 7.16E-06 5.14478591 -0.432282386 IDFSSIAVPGTSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 IDFSSIAVPGTSSPR 15 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 0 IDFSSIAVPGT(0.003)S(0.068)S(0.929)PR;IDFSSIAVPGT(0.034)S(0.317)S(0.648)PR ; 190.18 2.74E-06 474910000 5353.2 4340.2 4906.5 5098.9 4911.1 7063.9 6521.2 3834.9 5764.4 4356.1 TRUE FALSE FALSE 4929.488571 4715.347548 5088.339206 5077.802103 4852.53834 5598.767513 6704.167321 5004.143356 5132.059742 4507.474151 1.093625478 1.046117491 1.128867085 1.126529389 1.076553781 1.242107514 1.487344596 1.110187921 1.13856665 1 12.1381035 -5.201152925 3.532451744 1.059237808 1.311333759 0.441436018 0.096469224 0.123941931 3.090577977 0.012720428 0.03460524 6.29E-06 5.201152925 0.252095951 IDFT(ph)PVSPAPS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 IDFTPVSPAPSPTR 14 0 Q7Z309;Q7Z309-2;G1UD79;Q7Z309-5;Q7Z309-4;Q7Z309-3 Q7Z309 FAM122B;SPACIA2 Protein FAM122B 2 0 IDFT(0.5)PVS(0.5)PAPS(0.758)PT(0.242)R 136.57 0.0039491 7817800 3826.3 3501.2 3435.4 3978.6 4021.8 4645.2 4134.5 2729.4 3416.1 3757.2 TRUE FALSE FALSE 3523.444318 3803.828127 3562.718946 3962.137607 3973.842662 3681.733158 4250.502943 3561.581495 3041.362377 3887.76242 0.906291058 0.978410642 0.916393175 1.01913059 1.022141333 0.947005696 1.093303161 0.916100602 0.782291212 1 11.92472434 -6.244894709 24.74285505 0.954001389 1.003083019 0.154758882 0.074402788 1012.666015 1514460.61 0.007933865 0.013130803 5.69E-07 6.244894709 0.049081631 IDFYFDENPYFENK ddPTM_HeLa_Curcumin_4h_R1 1 IDFYFDENPYFENK 14 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 0 314.74 8.41E-107 117800000 2719.7 2166.7 2461.5 2454 2449.7 3304.3 2651.6 2783.6 2646.1 2170.6 FALSE FALSE TRUE 2504.432875 2353.979893 2552.725355 2443.845998 2420.488927 2618.950933 2725.99676 3632.306826 2355.82945 2246.028188 1.115049619 1.048063379 1.136550898 1.0880745 1.077675222 1.166036538 1.213696593 1.617213375 1.048886858 1 11.13316032 -1.000000026 0.829325369 1.062152124 171.27729 0.943794328 0.039398597 110.6258528 0.318578008 0.007928583 35490.08316 0.099999994 1.000000026 170.2151379 IDGATQSS(ph)PAEPK ddPTM_HeLa_Curcumin_4h_R1 4 IDGATQSSPAEPK 13 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 0 IDGATQS(0.064)S(0.936)PAEPK;IDGAT(0.002)QS(0.348)S(0.65)PAEPK;IDGATQS(0.226)S(0.774)PAEPK;IDGATQS(0.062)S(0.938)PAEPK ;;; 209.19 2.79E-09 1438360000 32080.9 27398.1 28321 29361 28552.9 32281 25540.5 23027.9 28555 22965.6 TRUE FALSE FALSE 29541.66291 29766.26968 29370.60117 29239.51196 28212.42532 25585.55672 26257.09769 30049.0007 25422.58794 23763.65289 1.243144859 1.252596552 1.235946397 1.230430023 1.187209115 1.076667667 1.104926831 1.264494177 1.069809766 1 14.536469 -9.318038182 1.02937606 0.999394379 1.198258953 0.51389778 0.062811249 0.314684534 0.594255212 0.045563099 0.011944288 4.81E-10 9.318038182 0.198864574 IDGATQSS(ph)PAEPKSEDADR ddPTM_HeLa_Curcumin_4h_R1 2 IDGATQSSPAEPKSEDADR 19 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 0 IDGAT(0.028)QS(0.245)S(0.727)PAEPKSEDADR;IDGATQS(0.097)S(0.903)PAEPKSEDADR ; 189.45 7.36E-09 134262000 6293 4805.2 4920.6 5499.6 3864.35 6279.4 4854.9 3798.3 6929.8 5872.7 TRUE FALSE FALSE 5794.90241 5220.540076 5102.961765 5476.844112 3818.27015 4976.981657 4991.115428 4956.384185 6169.618278 6076.775888 0.953614633 0.859097023 0.839748225 0.901274658 0.628338155 0.819016819 0.821342686 0.815627279 1.015278232 1 12.56909037 -7.037191883 0.885642867 0.988075139 0.786882255 0.635348378 0.064224339 0.237238881 0.370425582 0.013624982 0.01842042 9.18E-08 7.037191883 -0.201192883 IDHYLGK ddPTM_HeLa_Curcumin_4h_R1 1 IDHYLGK 7 0 P11413;P11413-3;P11413-2;E9PD92;E7EM57;E7EUI8 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 0 100.19 0.015657 25934000 10020 8152.2 9185.4 9704.8 10086 10682 8571.2 8242.8 9275.8 9418.1 FALSE FALSE TRUE 9226.906427 8856.839843 9525.819004 9664.644109 9965.731037 8466.432789 8811.684804 10755.99177 8258.267947 9745.378274 0.946798181 0.908824634 0.977470421 0.991715646 1.022611002 0.868763895 0.904191152 1.103701824 0.84740353 1 13.25050247 -9.404775987 1.196134297 0.999475283 0.960346082 0 0.079186461 1.254473301 3.275550115 0.039118874 0.010503935 3.94E-10 9.404775987 -0.039129201 IDIFPAKENGDLS(ph)PFSGTSLR ddPTM_HeLa_Curcumin_4h_R1 2 IDIFPAKENGDLSPFSGTSLR 21 1 V9GY71;V9GYH5;P19174 V9GY71 PLCG1 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1" 1 0 IDIFPAKENGDLS(0.853)PFS(0.124)GT(0.016)S(0.007)LR;IDIFPAKENGDLS(0.723)PFS(0.115)GT(0.047)S(0.115)LR ; 69.084 0.0014963 49709000 3421.1 2781.5 2528.72 2939.7 2842.9 4168.5 2597.1 3798.8 3799.9 3353.5 TRUE FALSE FALSE 3150.316325 3021.920466 2622.436588 2927.5363 2809.000274 3303.906111 2669.967636 4957.036632 3383.060477 3470.033875 0.907863277 0.87086195 0.755738037 0.843662167 0.809502263 0.952125031 0.769435611 1.42852687 0.974935865 1 11.76073403 -4.251779983 24.91161735 0.909623394 1.428527162 0.782700378 0.08570534 520.4373877 1342181.477 0.013499358 0.235730784 5.60E-05 4.251779983 0.518903768 IDIFPAKQENGDLS(ph)PFSGTSLR ddPTM_HeLa_Curcumin_4h_R1 2 IDIFPAKQENGDLSPFSGTSLR 22 1 P19174-2 P19174-2 PLCG1 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1" 1 0 IDIFPAKQENGDLS(0.852)PFS(0.122)GT(0.019)S(0.008)LR;IDIFPAKQENGDLS(0.825)PFS(0.134)GT(0.018)S(0.023)LR ; 57.648 0.0054229 91647000 4247.1 3107 2912.7 3670.5 3022.6 4772.5 3611.4 4992.4 4980.6 3736 TRUE FALSE FALSE 3910.937553 3375.555235 3020.647224 3655.312444 2986.557469 3782.629703 3712.726164 6514.559778 4434.240641 3865.825722 1.011669391 0.873178327 0.781371806 0.945545068 0.772553572 0.978479108 0.960396674 1.685166442 1.147035837 1 11.91656088 -4.261424429 9.540480241 0.958184488 1.687496903 0.813271484 0.106673919 0.023245983 54.72069269 0.013920165 0.108310532 5.48E-05 4.261424429 0.729312416 IDIIPNPQER ddPTM_HeLa_Curcumin_4h_R1 1 IDIIPNPQER 10 0 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 0 112.75 0.0045314 15889000 2150.9 1482.9 1807.8 1719.5 1866.1 2178.2 1518.8 1724.8 2022.8 1656.3 FALSE FALSE TRUE 1980.653995 1611.075268 1874.798658 1712.385165 1843.847976 1726.416767 1561.41344 2250.68358 1800.903901 1713.856302 1.155670982 0.940029375 1.093906564 0.999141622 1.075847476 1.007328774 0.911052717 1.313227706 1.050790489 1 10.74303044 -7.289191601 24.97353892 1.073511284 1.042649179 0.004430272 0.109818689 3277.178191 2949046.613 0.018604523 0.021277417 5.14E-08 7.289191601 -0.030862105 IDILDSALLRPGR ddPTM_HeLa_Curcumin_4h_R1 2 IDILDSALLRPGR 13 1 P62195;P62195-2 P62195 PSMC5 26S protease regulatory subunit 8 0 0 ; ; 173.76 0.00017934 11051400 4439.9 3553.5 3934.1 3786.1 3582.3 6367.9 4604.1 3966.3 4622 4343.6 FALSE FALSE TRUE 4088.47723 3860.648706 4079.901207 3770.434121 3539.583412 5047.125759 4733.278655 5175.606611 4114.978164 4494.539777 0.909654255 0.858964187 0.907746156 0.838892147 0.787529667 1.122946066 1.053117536 1.151532052 0.915550505 1 12.13395768 -5.232904593 24.78673675 0.926130294 1.103590495 0.683657075 0.065368633 401.7586037 348986.9533 0.011039624 0.028139931 5.85E-06 5.232904593 0.177460201 IDINMSGFNETDDLKR ddPTM_HeLa_Curcumin_4h_R1 1 IDINMSGFNETDDLKR 16 1 P13797;A0A0A0MSQ0;P13797-3;P13797-2;H7C4N2 P13797 PLS3 Plastin-3 0 0 100.23 0.00075609 0 537.67 432.63 485.96 499.54 613.49 629.93 266.01 637.52 619.22 310.91 FALSE FALSE TRUE 495.1128522 470.0246094 503.9701051 497.4730358 606.1745324 499.2754172 273.4735247 831.8969132 551.2931152 321.7140994 1.538984002 1.461000964 1.566515444 1.546320279 1.884202569 1.551922711 0.850051413 2.585826717 1.713611919 1 8.329635354 -11.16337604 0.206963997 4.45E-12 1.73549813 0 0.456346763 18.959388 0.556295981 8.924923387 0.420019787 6.86E-12 11.16337604 1.73549813 IDIS(ph)PSTFR ddPTM_HeLa_Curcumin_4h_R1 6 IDISPSTFR 9 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 IDIS(0.969)PS(0.031)TFR;IDIS(0.955)PS(0.032)T(0.013)FR;IDIS(0.988)PS(0.011)TFR;IDIS(0.952)PS(0.048)TFR;IDIS(0.998)PS(0.002)TFR;IDIS(0.976)PS(0.024)TFR ;;;;; 160.91 0.00069667 3162814000 17447.7 14932.2 16932.5 17073 16283.3 19914.8 16202.7 14728.1 17495.1 15968.2 TRUE FALSE FALSE 16066.69613 16222.87283 17560.03335 17002.35645 16089.13228 15784.24599 16657.30415 19218.62989 15575.9313 16523.09376 0.972378198 0.981830223 1.062756987 1.029005627 0.973736064 0.955283933 1.008122595 1.163137495 0.942676446 1 14.01219622 -4.268043594 4.387132171 0.991804556 1.174413848 0.707033764 0.033250146 0.077213135 3.581978813 0.004337148 0.043251613 5.39E-05 4.268043594 0.182609292 IDIS(ph)PSTLR ddPTM_HeLa_Curcumin_4h_R1 5 IDISPSTLR 9 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 IDIS(0.599)PS(0.4)T(0.001)LR;IDIS(0.961)PS(0.037)T(0.002)LR;IDIS(0.756)PS(0.243)T(0.001)LR;IDIS(0.982)PS(0.018)TLR;IDIS(0.636)PS(0.363)T(0.001)LR ;;;; 126.39 0.0045811 3070773000 14459.8 12382.5 12981.5 12970.5 14184.5 15516.6 13574.9 12110.3 14007.8 12256.6 TRUE FALSE FALSE 13315.29157 13452.78812 13462.60581 12916.83151 14015.3591 12298.28225 13955.77516 15802.67472 12471.17939 12682.51594 1.049893541 1.060734967 1.061509079 1.01847548 1.105092962 0.96970367 1.100394845 1.24602049 0.983336386 1 13.63055335 -4.354366429 3.083295331 1.031928491 1.259536241 0.734015852 0.039184566 0.105730092 1.576248183 0.005068042 0.051002688 4.42E-05 4.354366429 0.22760775 IDISPSTFR ddPTM_HeLa_Curcumin_4h_R1 1 IDISPSTFR 9 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 0 0 163.9 5.04E-11 0 1762.9 1679.4 1443.2 1559.6 1390.8 1419.2 1584.5 1127.2 1683.2 1419.3 FALSE FALSE TRUE 1623.364605 1824.559853 1496.686262 1553.146788 1374.215618 1124.841922 1628.956806 1470.878091 1498.557171 1468.620569 1.105366926 1.242362998 1.01911024 1.057554838 0.935718624 0.765917314 1.109174718 1.001537171 1.020384163 1 10.520246 -5.778202094 10.60688788 1.064924589 0.950857278 0.25066844 0.101753007 0.418321089 256.8023618 0.015626383 0.028795873 1.67E-06 5.778202094 -0.114067312 IDISPSTLR ddPTM_HeLa_Curcumin_4h_R1 1 IDISPSTLR 9 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 0 141.52 0.019446 3361200 2573.7 1875.6 2509.5 2379.3 1920.4 2457.1 2422.8 2104.1 2555.2 1952 FALSE FALSE TRUE 2369.988929 2037.718506 2602.504278 2369.455087 1897.500484 1947.469763 2490.777247 2745.630404 2274.900953 2019.831855 1.173359517 1.008855515 1.288475707 1.173095217 0.939434874 0.9641742 1.233160692 1.359336124 1.126282343 1 10.98001948 -9.408810704 0.926190381 0.992509036 1.137705441 0.016233762 0.135770317 1.140318109 1.5979317 0.119891644 0.02475795 3.90E-10 9.408810704 0.145196405 IDKLMIEMDGTENK ddPTM_HeLa_Curcumin_4h_R1 2 IDKLMIEMDGTENK 14 1 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879 P06733 ENO1 Alpha-enolase;Enolase 0 0 ; ; 134.06 0.00082719 32301000 2029.34 1947.05 2131.33 2160.37 1815.56 2625.03 2001.45 2797.5 2339.2 2209.13 FALSE FALSE TRUE 1868.715598 2115.344326 2210.318965 2151.430961 1793.910633 2080.569188 2057.6053 3650.444872 2082.595612 2285.897103 0.817497688 0.925389128 0.966937209 0.941175768 0.784773134 0.910176221 0.900130324 1.596941904 0.911062711 1 11.15854475 -4.260997016 24.79432529 0.908819246 1.596942137 0.920980617 0.060681606 7.823988075 438372.4112 0.010660309 0.083930107 5.48E-05 4.260997016 0.688122891 IDLPEVQIEHDPELEKES(ph)PGLK ddPTM_HeLa_Curcumin_4h_R1 2 IDLPEVQIEHDPELEKESPGLK 22 1 Q14966-3;Q14966;Q14966-5 Q14966-3 ZNF638 Zinc finger protein 638 1 0 IDLPEVQIEHDPELEKES(1)PGLK;IDLPEVQIEHDPELEKES(1)PGLK ; 81.967 0.00028788 22929000 9231.7 7847.2 8295.2 9931.5 8502.4 11291.9 9633.7 5765.4 10271.3 8361.4 TRUE FALSE FALSE 8501.001204 8525.477002 8602.627409 9890.406085 8401.014433 8949.832654 9903.995694 7523.243919 9144.564088 8651.958028 0.982552294 0.985381225 0.994298329 1.143140784 0.970995745 1.03442858 1.144711482 0.86954235 1.056935789 1 13.07881095 -6.47770834 24.99593671 0.990994315 1.038801581 0.017318948 0.077395848 797.2272778 441161.5595 0.010279443 0.015701595 3.33E-07 6.47770834 0.047807266 IDNDGDGFVTTEELK ddPTM_HeLa_Curcumin_4h_R1 1 IDNDGDGFVTTEELK 15 0 Q15293;Q15293-2 Q15293 RCN1 Reticulocalbin-1 0 0 163.99 0.0022044 4272500 1217.2 1078.9 1162.9 1236.2 1631.2 1623.7 1151.1 1013.9 1313 1241.2 FALSE FALSE TRUE 1120.857336 1172.155309 1205.998097 1231.084932 1611.749005 1286.926317 1183.396768 1323.033443 1168.967185 1284.331608 0.872716461 0.912657838 0.939008345 0.958541334 1.254932134 1.00202028 0.921410608 1.030133834 0.910175517 1 10.32680203 -5.97581807 24.99994092 0.936393484 1.047649671 0.330207475 0.084053149 249.4842031 257922.2814 0.013448779 0.024377212 1.06E-06 5.97581807 0.111256187 IDQLEGDHQLIQEALIFDNK ddPTM_HeLa_Curcumin_4h_R1 1 IDQLEGDHQLIQEALIFDNK 20 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8;H0YJW3;H0YJ11 P12814-4 ACTN1 Alpha-actinin-1 0 0 155.49 1.28E-05 16737000 3194 1577 3302.7 2218.7 3174.8 4625.1 3665 4136.4 2111.2 1662.5 FALSE FALSE TRUE 2941.19153 1713.308853 3425.100967 2209.519607 3136.942584 3665.802124 3767.830036 5397.569318 1879.606642 1720.271751 1.709724948 0.995952443 1.9910232 1.284401494 1.823515721 2.130943627 2.190252809 3.137625968 1.092621931 1 10.74842077 -1 0.329252355 1.25442492 19.34819 0.790800387 0.293136368 18.63483126 0.236636758 0.100479642 207.8456816 0.1 1 18.09376508 up IDREGK(ac)PR ddPTM_HeLa_Curcumin_4h_R1 1 IDREGKPR 8 2 P25398 P25398 RPS12 40S ribosomal protein S12 0 1 IDREGK(1)PR 98.523 0.0033136 881640 867.82 568.48 398.32 623.4 603.8 590.93 489.04 478.41 580.52 736.72 FALSE TRUE FALSE 799.1311313 617.6168781 413.0820896 620.820536 596.6000794 468.3644568 502.7611462 624.2750067 516.8384084 762.3209652 1.048286965 0.810179578 0.541874235 0.814382084 0.78261009 0.614392727 0.659513734 0.818913601 0.677980053 1 9.574254743 -7.123360088 4.04483067 1.022458338 0.705521667 0.187266854 0.137594382 0.080275924 2.258243124 0.013676697 0.016929774 7.53E-08 7.123360088 -0.316936671 IDRPEAISEER ddPTM_HeLa_Curcumin_4h_R1 1 IDRPEAISEER 11 1 D6RD69;Q9Y6B6;D6R9R5;Q9H029 D6RD69 SAR1B;DKFZp434B2017 GTP-binding protein SAR1b 0 0 98.182 0.01052 8329300 4494.5 4324.6 4463.4 3973.8 4812.4 5306.3 3941.9 4953.7 4585 3865.8 FALSE FALSE TRUE 4138.755582 4698.399154 4628.81753 3957.357469 4755.015273 4205.713566 4052.499105 6464.060326 4082.036971 4000.136262 1.03465365 1.174559776 1.157164963 0.989305666 1.188713324 1.051392575 1.013090265 1.615960033 1.02047448 1 11.96583343 -4.259270182 24.98864008 1.048459691 1.61596023 0.826470302 0.074478236 58.72335441 676431.7872 0.010956146 0.096905027 5.50E-05 4.259270182 0.567500538 IDS(ph)ATGAVS(ph)TDSVLDRETK ddPTM_HeLa_Curcumin_4h_R1 1 IDSATGAVSTDSVLDRETK 19 1 Q9NYQ6-2;Q9NYQ6 Q9NYQ6-2 CELSR1 Cadherin EGF LAG seven-pass G-type receptor 1 2 0 IDS(0.997)AT(0.046)GAVS(0.421)T(0.33)DS(0.206)VLDRETK 78.244 0.019961 8022200 17310 13685 14845 17803 16991 20304 14319 8243.6 20699 15780 TRUE FALSE FALSE 15939.89523 14867.87042 15395.16876 17729.3359 16788.39342 16092.72153 14720.7526 10757.03569 18428.37149 16328.35383 0.976209568 0.91055538 0.942848797 1.085800571 1.028174279 0.985569133 0.90154542 0.658794867 1.128611719 1 13.99509173 -4.269162077 2.205455041 0.989318682 0.575480727 0.737108402 0.062432602 0.187641681 1.04081856 0.006540555 0.150485854 5.38E-05 4.269162077 -0.413837954 IDS(ph)LSAQLSQLQK ddPTM_HeLa_Curcumin_4h_R1 2 IDSLSAQLSQLQK 13 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 IDS(0.998)LS(0.002)AQLSQLQK;IDS(0.975)LS(0.025)AQLSQLQK ; 197.47 2.55E-06 8383500 2524.4 2525.9 2205.59 2174.48 2629 3180.1 2773.4 2538.1 2912.2 2279.2 TRUE FALSE FALSE 2324.591076 2744.227541 2287.331106 2165.482578 2597.650892 2520.511413 2851.21414 3311.955006 2592.738946 2358.40203 0.985663617 1.163596158 0.969864797 0.918199081 1.101445326 1.068736959 1.208960179 1.40432164 1.099362582 1 11.20359396 -4.075206486 0.925360366 1.001780588 1.749569033 0.719337427 0.071456995 0.87294696 0.447775365 0.009769088 0.70917454 8.41E-05 4.075206486 0.747788445 IDS(ph)PGFKPASQQVYR ddPTM_HeLa_Curcumin_4h_R1 1 IDSPGFKPASQQVYR 15 1 A0A087X0K9;G5E9E7;Q07157-2 A0A087X0K9 TJP1 Tight junction protein ZO-1 1 0 IDS(0.998)PGFKPAS(0.002)QQVYR 75.911 0.0090931 293290000 2541.8 1901.6 1970.7 2299.9 1794.3 2803 2205.6 1100 2519.5 1757 TRUE FALSE FALSE 2340.613848 2065.965831 2043.735876 2290.383623 1772.904144 2221.626204 2267.4832 1435.384936 2243.117153 1818.055619 1.287426976 1.136360081 1.124132757 1.259798435 0.975164965 1.221979229 1.247202328 0.789516515 1.233800072 1 10.82818062 -4.251083203 24.34556427 1.14641724 0.789516226 0.53502033 0.103732907 755.9503567 1777056.52 0.016808128 0.308060706 5.61E-05 4.251083203 -0.356901013 IDSFSVQS(ph)LDSR ddPTM_HeLa_Curcumin_4h_R1 1 IDSFSVQSLDSR 12 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 0 IDSFS(0.002)VQS(0.998)LDS(0.001)R 122.52 0.0033077 4811600 1406 1081.7 1314.5 1345 1542.1 1962.9 1379.4 1214.6 1627.7 1109.6 TRUE FALSE FALSE 1294.713616 1175.197328 1363.216526 1339.434746 1523.711465 1555.772414 1418.102252 1584.925949 1449.145382 1148.158517 1.127643611 1.023549719 1.187306897 1.166593921 1.327091548 1.355015348 1.235110161 1.380406908 1.262147483 1 10.16510612 -5.94656076 0.359577966 1.018053145 1.418764938 0.420185353 0.094815803 0.721733243 0.153912656 0.027362937 0.111795524 1.13E-06 5.94656076 0.400711793 IDSIEDRYPR ddPTM_HeLa_Curcumin_4h_R1 2 IDSIEDRYPR 10 1 Q13158 Q13158 FADD FAS-associated death domain protein 0 0 ; ; 106.2 0.0079708 16541400 5748.7 4284.2 4773.9 5325.1 4386.7 6122.7 4564.7 4289 5333 4859.7 FALSE FALSE TRUE 5293.684329 4654.507158 4950.824934 5303.066147 4334.391468 4852.783003 4692.773197 5596.696356 4747.983243 5028.574213 1.052720732 0.925611706 0.984538504 1.054586434 0.861952371 0.96504154 0.933221426 1.112978773 0.94420069 1 12.29593369 -7.275972207 24.79284597 1.024895901 0.973582018 0 0.071051536 1135.786388 1937635.171 0.010933589 0.012533801 5.30E-08 7.275972207 -0.051313882 IDSIPHLNNS(ph)TPLVDPSVYGYGVQK ddPTM_HeLa_Curcumin_4h_R1 1 IDSIPHLNNSTPLVDPSVYGYGVQK 25 0 Q96I24 Q96I24 FUBP3 Far upstream element-binding protein 3 1 0 IDSIPHLNNS(0.499)T(0.499)PLVDPS(0.001)VYGYGVQK 91.583 4.10E-05 0 698.18 366.24 536.81 704.73 652.95 942.7 1165.9 607.54 826.56 525.38 TRUE FALSE FALSE 642.9183163 397.8961537 556.7046508 701.814014 645.1639977 747.1733936 1198.612016 792.7761492 735.888436 543.6369159 1.182624464 0.731915258 1.024037615 1.290960922 1.186755312 1.374397823 2.204802472 1.458282405 1.353639561 1 9.086499616 -5.005515589 3.673235499 1.080047749 1.834929492 0.584728643 0.237996426 0.093413664 2.740724038 0.029798355 0.092068912 9.87E-06 5.005515589 0.754881743 IDTIEIITDR ddPTM_HeLa_Curcumin_4h_R1 4 IDTIEIITDR 10 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 ;;; ;;; 174.86 0.001987 64051700 11330.8 9140 10755.2 9742.1 12153.4 13726.3 12201.6 10492.5 9761.6 8999.1 FALSE FALSE TRUE 10433.95522 9930.020873 11153.79717 9701.789772 12008.47864 10879.31065 12543.94406 13691.61495 8690.776902 9311.818055 1.120506776 1.066389057 1.197810901 1.041879224 1.289595498 1.16833368 1.347099351 1.470348203 0.933306133 1 13.18484715 -1 0.278664287 1.032178673 4.260717231 0.791957194 0.072227585 14.02206275 0.178598016 0.026947489 22.30229171 0.1 1 3.228538558 IDVDAPDIDIHGPDAK ddPTM_HeLa_Curcumin_4h_R1 2 IDVDAPDIDIHGPDAK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 142.57 0.00030691 16335700 6469.2 4653.4 4752.9 5410.7 5225.9 6565 4872.3 5049.3 6025.1 4418.1 FALSE FALSE TRUE 5957.155994 5055.619161 4929.046655 5388.311957 5163.584556 5203.344997 5009.003625 6588.808326 5364.161604 4571.628646 1.303070843 1.105868292 1.078181768 1.178641656 1.129484688 1.138181904 1.095671589 1.441238744 1.173358997 1 12.1584925 -9.596261255 1.39629159 1.000180756 1.18947293 0.020067945 0.117408004 0.427197897 1.49654763 0.075219204 0.017492962 2.53E-10 9.596261255 0.189292174 IDVPQDLEDDLTATPLSHAT(ph)VPQSPAR ddPTM_HeLa_Curcumin_4h_R1 1 IDVPQDLEDDLTATPLSHATVPQSPAR 27 0 E7EUC4;Q9NRH2 E7EUC4 SNRK SNF-related serine/threonine-protein kinase 1 0 IDVPQDLEDDLTATPLS(0.026)HAT(0.857)VPQS(0.118)PAR 138.82 4.47E-08 8904500 1271.2 1161.7 1069.7 793.41 2087.4 3026 1578.8 1247.8 1858.6 1310.5 TRUE FALSE FALSE 1170.583179 1262.112172 1109.344023 790.1270796 2062.509118 2398.37349 1623.096879 1628.248476 1654.71623 1356.039777 0.863236609 0.930733886 0.818076314 0.582672494 1.520979807 1.768660131 1.196938988 1.200737989 1.22025641 1 10.40518378 -5.745365344 24.99976051 0.901698266 1.430539405 0.588649617 0.212630738 119.2268402 185431.0651 0.028306621 0.056470968 1.80E-06 5.745365344 0.528841139 IDVPQDLEDDLTATPLSHATVPQS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 1 IDVPQDLEDDLTATPLSHATVPQSPAR 27 0 E7EUC4;Q9NRH2 E7EUC4 SNRK SNF-related serine/threonine-protein kinase 1 0 IDVPQDLEDDLTAT(0.001)PLSHAT(0.057)VPQS(0.943)PAR 117.94 3.74E-09 3904300 1233.4 903.74 823.61 643.7 1330.4 2300.7 1021.8 1048 1169.5 1026.5 TRUE FALSE FALSE 1135.775089 981.8552586 854.1337111 641.03654 1314.535849 1823.508886 1050.468958 1367.530376 1041.208776 1062.170799 1.069296096 0.924385475 0.804139704 0.603515499 1.237593663 1.716775577 0.988983089 1.287486323 0.980264923 1 10.05280006 -5.541527026 24.99897276 0.976261694 1.326924022 0.454668004 0.211715711 189.9668317 254659.6099 0.031203312 0.062413951 2.87E-06 5.541527026 0.350662327 IDVT(ph)APDVSIEEPEGK ddPTM_HeLa_Curcumin_4h_R1 1 IDVTAPDVSIEEPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 IDVT(0.607)APDVS(0.393)IEEPEGK 135.14 0.001247 9186800 5518.9 4321.7 4214.8 4946.6 4643 7822.6 5018.6 3442.8 5355.5 4059.3 TRUE FALSE FALSE 5082.073241 4695.248491 4371.004196 4926.13228 4587.635257 6200.104581 5159.408409 4492.493871 4768.015049 4200.360373 1.209913624 1.117820395 1.040625996 1.172788009 1.092200395 1.476088724 1.22832518 1.069549627 1.135144279 1 12.03629739 -13.52287875 0.214119763 0.057201482 1.2157378 0.076144199 0.12231081 51.35431029 0.643254229 20.31506924 0.102399573 3.00E-14 13.52287875 1.158536318 IDVTAPDVS(ph)IEEPEGK ddPTM_HeLa_Curcumin_4h_R1 3 IDVTAPDVSIEEPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 IDVTAPDVS(1)IEEPEGK;IDVT(0.002)APDVS(0.998)IEEPEGK;IDVTAPDVS(1)IEEPEGK ;; 211.45 4.20E-11 50499000 18028 15118.8 17415.4 17599.5 17670.2 27363.4 18653.9 11165.3 18365.7 14084.8 TRUE FALSE FALSE 16601.06478 16425.6017 18060.83004 17526.67793 17459.49441 21687.92239 19177.27823 14569.54857 16351.02866 14574.24575 1.139068536 1.127029281 1.239229141 1.202578729 1.197968986 1.488099128 1.315833324 0.999677707 1.121912512 1 13.8311336 -7.655802437 0.465978066 1.006249099 1.269763073 0.23483566 0.120697671 0.659829739 0.364776085 0.062475304 0.051460007 2.21E-08 7.655802437 0.263513974 IEANEALVK ddPTM_HeLa_Curcumin_4h_R1 2 IEANEALVK 9 0 P30049 P30049 ATP5D "ATP synthase subunit delta, mitochondrial" 0 0 ; ; 111.61 0.0030971 4117100 2918.8 2740.2 3091.5 2875.3 3634.5 4338.2 2944.6 2879.3 3349 2620 FALSE FALSE TRUE 2687.7739 2977.050678 3206.07371 2863.40277 3591.160961 3438.408418 3027.217551 3757.185315 2981.623079 2711.044805 0.99141626 1.09811932 1.182597095 1.056198985 1.324640948 1.268296419 1.116623947 1.385880937 1.099805903 1 11.40463324 -6.468977821 0.766670912 0.991184605 1.266335657 0.514566656 0.089201294 0.270056558 0.316691663 0.0161075 0.032948328 3.40E-07 6.468977821 0.275151052 IECDDK(ac)GDGSCDVR ddPTM_HeLa_Curcumin_4h_R1 2 IECDDKGDGSCDVR 14 1 P21333-2;P21333;Q60FE5;A0A087WWY3;Q14315-2;Q14315 P21333-2;Q60FE5;Q14315-2 FLNA;FLNC Filamin-A;Filamin-C 0 1 ; IECDDK(1)GDGSCDVR;IECDDK(1)GDGSCDVR 238.07 1.93E-38 9266900 2394.5 2228.3 2774.9 2291.7 5657.9 7688.3 5011.4 4683.9 5548.8 2201.5 FALSE TRUE FALSE 2204.972798 2420.904323 2877.740235 2282.217553 5590.433238 6093.659915 5152.006397 6111.999548 4940.110522 2278.001961 0.967941572 1.062731448 1.263273818 1.001850565 2.454095007 2.67500205 2.261633872 2.683052803 2.16861557 1 11.15355327 -5.754574503 7.138317777 1.014267279 2.516342638 0.702184479 0.389798477 0.016205994 4.382513675 0.019299337 0.037291509 1.76E-06 5.754574503 1.502075359 IECDDKGDGSCDVR ddPTM_HeLa_Curcumin_4h_R1 1 IECDDKGDGSCDVR 14 1 P21333-2;P21333;Q60FE5;A0A087WWY3;Q14315-2;Q14315 P21333-2;Q60FE5;Q14315-2 FLNA;FLNC Filamin-A;Filamin-C 0 0 106.26 0.003053 100290000 6400.7 3236.7 5303.3 5178 6327.2 7429.4 4923.9 5034.4 4506.2 4491.4 FALSE FALSE TRUE 5894.077841 3516.465926 5499.844963 5156.574808 6251.752272 5888.458693 5062.051382 6569.365384 4011.881134 4647.475816 1.268232063 0.756639962 1.183404752 1.109543118 1.345193073 1.267022988 1.089204459 1.413534066 0.863238733 1 12.18223164 -5.794454405 16.02161308 1.102433385 1.2643589 0.292527086 0.167585636 5.293621926 2568.478376 0.023797181 0.043168824 1.61E-06 5.794454405 0.161925515 IECEIK(ac)INHEGEVNR ddPTM_HeLa_Curcumin_4h_R1 2 IECEIKINHEGEVNR 15 1 E9PC52;Q16576;Q16576-2;Q5JP01 E9PC52 RBBP7 Histone-binding protein RBBP7 0 1 ; IECEIK(1)INHEGEVNR;IECEIK(1)INHEGEVNR 130.06 0.00084225 41676000 7698.9 6463.5 7245.7 7102.9 7311 9057 7147.2 6339.4 7588.4 7584.3 FALSE TRUE FALSE 7089.523941 7022.176139 7514.232016 7073.510082 7223.8211 7178.476107 7347.731196 8272.253877 6755.971505 7847.85386 0.903371045 0.894789361 0.95748878 0.901330505 0.920483642 0.91470563 0.936272684 1.054078481 0.860868669 1 12.93808246 -9.44181451 1.191360698 0.999744606 0.929725408 0 0.061394437 0.51438691 1.313302392 0.029219565 0.007402377 3.62E-10 9.44181451 -0.070019198 IEDDMDGGDWSFCDGR ddPTM_HeLa_Curcumin_4h_R1 2 IEDDMDGGDWSFCDGR 16 0 P23229-9;C9JXX7;P23229-7;P23229-4;P23229-2;P23229-5;P23229-3;P23229-6;P23229 P23229-9 ITGA6 Integrin alpha-6;Integrin alpha-6 heavy chain;Integrin alpha-6 light chain;Processed integrin alpha-6 0 0 ; ; 176.99 0.00018667 9576800 2219 1856.65 1829.37 2501.9 2082.77 2951.2 1921.76 1683.04 2885.4 1987.55 FALSE FALSE TRUE 2043.363809 2017.130553 1897.168061 2491.547801 2057.934328 2339.087853 1975.679413 2196.191148 2568.878839 2056.617215 0.993555725 0.980800189 0.922470185 1.211478628 1.000640427 1.137347211 0.96064518 1.067865781 1.249079712 1 11.00605758 IEDFLER ddPTM_HeLa_Curcumin_4h_R1 2 IEDFLER 7 0 P46781;B5MCT8;C9JM19 P46781 RPS9 40S ribosomal protein S9 0 0 ; ; 153.73 5.75E-05 6379300 7869.8 7504.7 6521.3 7303.7 7140.4 7201.3 6901.2 5782.1 7255.2 6511.9 FALSE FALSE TRUE 7246.897026 8153.372828 6762.985115 7273.479225 7055.255394 5707.669205 7094.829098 7545.035672 6459.322712 6738.18804 1.075496407 1.210024532 1.003680081 1.079441414 1.047055284 0.847062915 1.052928333 1.119742522 0.958614196 1 12.71814497 -5.482326557 24.97439003 1.051571564 1.000520687 0.052939752 0.089755477 1184.007814 729180.1691 0.012425092 0.027779735 3.29E-06 5.482326557 -0.051050877 IEDFLERR ddPTM_HeLa_Curcumin_4h_R1 5 IEDFLERR 8 1 P46781;B5MCT8;C9JM19 P46781 RPS9 40S ribosomal protein S9 0 0 ;;;; ;;;; 134.48 0.0036189 31120310 16530.8 14274.9 11675.2 14769.2 10291.22 15225.4 11655.54 11750.4 18395.9 16796.4 FALSE FALSE TRUE 15222.36974 15508.75875 12107.89318 14708.08896 10168.50392 12067.48041 11982.56308 15333.04287 16377.91579 17380.07365 0.875851854 0.892329864 0.696653733 0.846261602 0.585066791 0.694328497 0.689442595 0.882219672 0.942338688 1 14.08514658 -7.309696581 0.63585354 0.975718059 0.713989097 0.541069079 0.086387597 0.326081855 0.288244645 0.025310556 0.029043137 4.90E-08 7.309696581 -0.261728962 IEDHLLS(ph)SGKFMYLEGNADS(ph)AMS ddPTM_HeLa_Curcumin_4h_R1 1 IEDHLLSSGKFMYLEGNADSAMS 23 1 O14763-2;O14763 O14763-2 TNFRSF10B Tumor necrosis factor receptor superfamily member 10B 2 0 IEDHLLS(0.499)S(0.499)GKFMY(0.002)LEGNADS(0.573)AMS(0.426) 51.524 0.015982 41104000 1077.2 889.97 983.73 998.45 858.3 1051.2 704.05 722.6 1066 1016.6 TRUE FALSE FALSE 991.9384833 966.8950412 1020.187899 994.3186785 848.0653331 833.1692705 723.8037481 942.9174136 949.062467 1051.926774 0.94297294 0.91916573 0.969827866 0.945235641 0.80620187 0.79204113 0.688074271 0.896371721 0.902213434 1 10.03881857 -5.75883769 3.320357693 0.967143809 0.78338888 0.635322495 0.054889977 0.089535909 2.06100624 0.007419569 0.014951429 1.74E-06 5.75883769 -0.183754929 IEDS(ph)EPHIPLIDDTDAEDDAPTKR ddPTM_HeLa_Curcumin_4h_R1 2 IEDSEPHIPLIDDTDAEDDAPTKR 24 1 P20020-1;E7ERY9;P20020-4;P20020-6;P20020;A0A0U1RQU3;H0YHH6 P20020-1 ATP2B1 Plasma membrane calcium-transporting ATPase 1;Calcium-transporting ATPase 1 0 IEDS(1)EPHIPLIDDTDAEDDAPTKR;IEDS(1)EPHIPLIDDTDAEDDAPTKR ; 79.373 0.00025146 15275000 14622 12278.4 13923.7 20491 13963.7 15665 7842.9 6166.1 23906.5 15777.4 TRUE FALSE FALSE 13464.65327 13339.69018 14439.72457 20406.21367 13797.192 12415.90242 8062.950666 8046.115505 21284.01676 16325.66348 0.824753817 0.817099422 0.884480107 1.249946975 0.845122896 0.760514416 0.493881959 0.492850751 1.30371527 1 13.994854 -4.936256133 2.2292997 0.926686633 0.477727812 0.565501882 0.168139976 0.147493115 1.425479071 0.018542384 0.07640551 1.16E-05 4.936256133 -0.448958822 IEDSGENLETEPLESQDRELLDT(ph)SFEDLSKPK ddPTM_HeLa_Curcumin_4h_R1 1 IEDSGENLETEPLESQDRELLDTSFEDLSKPK 32 2 P78345 P78345 RPP38 Ribonuclease P protein subunit p38 1 0 IEDSGENLET(0.032)EPLES(0.026)QDRELLDT(0.449)S(0.449)FEDLS(0.044)KPK 52.669 0.0020925 59424000 3297.5 2542.9 2532.6 2972.6 2917.4 3779.5 2788 1363.8 3776.3 3097.5 TRUE FALSE FALSE 3036.499395 2762.696945 2626.460384 2960.300169 2882.61191 2995.589096 2866.223776 1779.616342 3362.049338 3205.137894 0.947384947 0.861958841 0.819453163 0.923610861 0.899372197 0.934620973 0.894259115 0.55523862 1.048956222 1 11.64617071 -4.237511735 2.899015016 0.944047963 0.474662282 0.758921016 0.062434442 0.168445049 1.891160064 0.009262068 0.189271599 5.79E-05 4.237511735 -0.469385681 IEDVGS(ph)DEEDDSGK ddPTM_HeLa_Curcumin_4h_R1 7 IEDVGSDEEDDSGK 14 0 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 0 IEDVGS(1)DEEDDSGK;IEDVGS(0.99)DEEDDS(0.01)GK;IEDVGS(1)DEEDDSGK;IEDVGS(1)DEEDDSGK;IEDVGS(0.878)DEEDDS(0.122)GK;IEDVGS(0.984)DEEDDS(0.016)GK;IEDVGS(1)DEEDDSGK ;;;;;; 293.8 3.12E-77 1589501100 20066.11 21685.5 23689.48 19213.19 29921.2 21662.72 20453.6 20809.7 16476.72 16285.14 TRUE FALSE FALSE 18477.85622 23559.89799 24567.43297 19133.69091 29564.40923 17169.62768 21027.47297 27154.48173 14669.26504 16851.0474 1.096540516 1.398126623 1.457917267 1.135460037 1.754455288 1.018905666 1.247843678 1.611441775 0.870525415 1 14.04055065 -7.352697112 3.776733896 1.041076188 1.365152568 0.409795664 0.209836212 0.184678303 4.781020453 0.033272315 0.037992091 4.44E-08 7.352697112 0.32407638 IEDVGS(ph)DEEDDSGKDK ddPTM_HeLa_Curcumin_4h_R1 15 IEDVGSDEEDDSGKDK 16 1 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 0 IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(0.984)DEEDDS(0.016)GKDK;IEDVGS(0.974)DEEDDS(0.026)GKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK;IEDVGS(1)DEEDDSGKDK ;;;;;;;;;;;;;; 257.16 2.17E-39 34331124800 35351 32138.33 34449.7 33295.3 40108.5 38379.9 31637.7 30233.34 30501.1 30113.7 TRUE FALSE FALSE 32552.93105 34916.22404 35726.43619 33157.53287 39630.23233 30419.47611 32525.36871 39451.34619 27155.20564 31160.14883 1.044697547 1.120540991 1.14654254 1.064100594 1.271824231 0.976230129 1.043813009 1.266083368 0.87147227 1 14.9274145 -7.445868853 1.763556704 1.015771132 1.122970978 0.318527375 0.098007887 0.353318922 2.140522768 0.01601212 0.017700722 3.58E-08 7.445868853 0.107199846 IEDVGS(ph)DEEDDSGKDKK ddPTM_HeLa_Curcumin_4h_R1 1 IEDVGSDEEDDSGKDKK 17 2 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 0 IEDVGS(0.997)DEEDDS(0.003)GKDKK 75.743 0.0095266 10613000000 3076.5 2707 3128.7 2560.8 3357.8 3274.2 2873.2 3030.7 2594.1 2475.3 TRUE FALSE FALSE 2832.991779 2940.981018 3244.652374 2550.204088 3317.760428 2595.094012 2953.814259 3954.746478 2309.53372 2561.316491 1.106068613 1.148230228 1.266790881 0.995661449 1.295334036 1.013187563 1.153240636 1.54402882 0.901697907 1 11.32266982 -4.272567689 3.510231507 1.08501791 1.594022665 0.572543777 0.11660459 0.135662887 2.920780191 0.014436197 0.179420896 5.34E-05 4.272567689 0.509004755 IEDVGSDEEDDS(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 IEDVGSDEEDDSGK 14 0 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 0 IEDVGS(0.007)DEEDDS(0.993)GK 160.63 0.00028808 419920000 5388.6 5290.6 6753.3 5049.5 7779.8 5700 5876.6 5733.9 3544.7 3623.1 TRUE FALSE FALSE 4962.086624 5747.89589 7003.583239 5028.606507 7687.030966 4517.755748 6041.48158 7482.139714 3155.855278 3749.002455 1.323575186 1.533180081 1.868119139 1.341318542 2.050420361 1.205055425 1.61149043 1.995768155 0.841785333 1 11.87229106 -7.757324246 0.665257905 1.03986517 1.678477771 0.544633132 0.263009126 0.359650423 0.35750831 0.084250516 0.069659082 1.75E-08 7.757324246 0.638612602 IEDVGSDEEDDS(ph)GKDK ddPTM_HeLa_Curcumin_4h_R1 1 IEDVGSDEEDDSGKDK 16 1 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 0 IEDVGS(0.323)DEEDDS(0.677)GKDK 65.808 0.013554 34277000 1810.7 1691.4 1993.1 1560.1 2177.8 2041.3 1597.4 1883.6 1794.1 1706.3 TRUE FALSE FALSE 1667.381184 1837.597079 2066.966039 1553.64472 2151.831157 1617.91137 1642.218745 2457.900969 1597.291719 1765.593798 0.944374174 1.04078134 1.170691719 0.879955923 1.218757769 0.916355377 0.930122629 1.392110106 0.904676784 1 10.78593775 -4.255625457 24.59291245 0.994921191 1.392110324 0.539637645 0.108358 272.1832298 1151292.665 0.013455845 0.160027622 5.55E-05 4.255625457 0.397189134 IEDVGSDEEDDS(ph)GKDKK ddPTM_HeLa_Curcumin_4h_R1 2 IEDVGSDEEDDSGKDKK 17 2 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 1 0 IEDVGS(0.051)DEEDDS(0.949)GKDKK;IEDVGS(0.141)DEEDDS(0.859)GKDKK ; 82.651 0.0058187 413441000 7815.9 10332.4 7720.8 7866.5 8634.7 7463.4 7446.1 7679.1 6373.7 6618.5 TRUE FALSE FALSE 7197.263268 11225.48662 8006.93964 7833.950507 8531.736842 5915.40671 7655.017526 10020.42224 5674.521056 6848.492382 1.050926666 1.639117924 1.169153617 1.14389417 1.245783213 0.863753127 1.117766816 1.46315739 0.828579597 1 12.74157071 -7.491929522 24.99740763 1.02246749 1.219938358 0.258446978 0.20476841 486.4280693 392887.4087 0.033879094 0.037020257 3.22E-08 7.491929522 0.197470868 IEDVGSDEEDDSGKDK ddPTM_HeLa_Curcumin_4h_R1 1 IEDVGSDEEDDSGKDK 16 1 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 0 96.734 0.0018602 0 832.23 997.84 976.07 1092.9 1261.5 1354.1 1004.4 748.16 907.57 698.05 FALSE FALSE TRUE 766.3581173 1084.088843 1012.244013 1088.377869 1246.457436 1073.244396 1032.580761 976.2705399 808.0118416 722.3071855 1.060986423 1.500869526 1.40140377 1.506807479 1.725661133 1.485855904 1.429559032 1.351600205 1.118654027 1 9.496468712 -7.282231595 4.959028122 1.02689959 1.491753239 0.79667054 0.098254169 0.053871814 3.7784957 0.016999203 0.019821058 5.22E-08 7.282231595 0.464853649 IEDVGSDEEDDSGKDKK ddPTM_HeLa_Curcumin_4h_R1 2 IEDVGSDEEDDSGKDKK 17 2 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 0 ; ; 120.9 0.00023388 50520000 9100.3 7622.6 9065.5 7131.5 9444.1 9624.2 8063.8 6983.4 8287 7856.8 FALSE FALSE TRUE 8380.001652 8281.463578 9401.475405 7101.991743 9331.485276 7628.032433 8290.048525 9112.606512 7377.936833 8129.823215 1.030772925 1.018652357 1.156418185 0.873572715 1.147809126 0.938277774 1.019708339 1.120886183 0.907515039 1 12.98900827 IEDVTPIPSDS(ph)TR ddPTM_HeLa_Curcumin_4h_R1 3 IEDVTPIPSDSTR 13 0 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 1 0 IEDVTPIPSDS(0.771)T(0.229)R;IEDVTPIPSDS(0.904)T(0.096)R;IEDVTPIPS(0.08)DS(0.793)T(0.127)R ;; 154.23 0.00041424 170263000 10003.1 7974.2 5910.9 6810 6611.7 8878 8671.4 5361.3 9341.5 6271.3 TRUE FALSE FALSE 9211.34408 8663.454316 6129.963154 6781.822024 6532.859796 7036.602724 8914.696146 6995.93569 8316.760821 6489.227208 1.419482441 1.335051777 0.944636851 1.045089316 1.00672385 1.084351418 1.373768534 1.078084565 1.281625771 1 12.66383096 -6.770470282 24.99961636 1.213895966 1.095813479 0.218716263 0.147767519 405.7916069 1123323.151 0.031515443 0.041750015 1.70E-07 6.770470282 -0.118082488 IEDVTPIPSDS(ph)TRR ddPTM_HeLa_Curcumin_4h_R1 3 IEDVTPIPSDSTRR 14 1 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 1 0 IEDVTPIPS(0.075)DS(0.741)T(0.183)RR;IEDVTPIPS(0.177)DS(0.646)T(0.177)RR;IEDVTPIPS(0.003)DS(0.967)T(0.03)RR ;; 137.27 0.00040029 47479500 15125.5 12116.3 7784.5 10441.1 10315.4 13825.5 12828.5 9000.7 14404 9906.1 TRUE FALSE FALSE 13928.30071 13163.57898 8073.000418 10397.89749 10192.39559 10957.93545 13188.43318 11744.972 12823.91724 10250.33624 1.358814032 1.284209481 0.787583961 1.014395748 0.99434744 1.069031805 1.286634202 1.14581334 1.251072837 1 13.32338361 IEDVTPIPSDSTR ddPTM_HeLa_Curcumin_4h_R1 2 IEDVTPIPSDSTR 13 0 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 0 0 ; ; 279.77 3.14E-94 14239800 4302.8 3105.4 3440.4 3648.9 4072.7 4198.9 3745.7 3123.2 3923.8 3792.1 FALSE FALSE TRUE 3962.22884 3373.816939 3567.90425 3633.801819 4024.135712 3328.000809 3850.794261 4075.449303 3493.368957 3923.875193 1.009774431 0.859817597 0.909280768 0.926074771 1.025551404 0.848141351 0.981375317 1.038628678 0.890285441 1 11.93806344 IEDVTPIPSDSTRR ddPTM_HeLa_Curcumin_4h_R1 2 IEDVTPIPSDSTRR 14 1 P62263;A0A2R8Y811 P62263 RPS14 40S ribosomal protein S14 0 0 ; ; 124.48 0.00076388 27946500 8201.9 6765.3 6928.6 6706.4 6727 8607 7352.7 5873.2 8185.1 8030.4 FALSE FALSE TRUE 7552.71096 7350.062386 7185.380011 6678.650694 6646.784919 6821.811179 7558.996973 7663.911643 7287.215008 8309.455802 0.908929675 0.884541968 0.864723296 0.803741045 0.799906164 0.820969669 0.909686164 0.922312101 0.876978611 1 13.02053828 -8.067805108 0.652194969 0.99134075 0.850521157 0.175073177 0.052866308 0.318205511 0.303568799 0.018718177 0.011982958 8.55E-09 8.067805108 -0.140819593 IEEAMDGS(ph)ETPQLFTVLPEKR ddPTM_HeLa_Curcumin_4h_R1 1 IEEAMDGSETPQLFTVLPEKR 21 1 E9PPJ0;Q13435 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 0 IEEAMDGS(0.54)ET(0.46)PQLFTVLPEKR 93.371 0.00023675 35966000 4717.5 3951.4 4386.3 5230.8 4062.4 6690.1 5602.9 5536.8 5479.8 4846 TRUE FALSE FALSE 4344.104897 4292.941409 4548.860137 5209.156336 4013.958533 5302.497847 5760.102295 7224.944832 4878.67965 5014.398139 0.866326282 0.856122966 0.907159745 1.038839795 0.800486603 1.057454494 1.148712594 1.440839884 0.972934241 1 12.29186083 -4.335880857 1.360490884 0.926945613 1.60862352 0.830626027 0.072250489 0.348075252 0.617566269 0.011292126 0.312489496 4.61E-05 4.335880857 0.681677906 IEEAMDGSET(ph)PQLFTVLPEKR ddPTM_HeLa_Curcumin_4h_R1 5 IEEAMDGSETPQLFTVLPEKR 21 1 E9PPJ0;Q13435 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 0 IEEAMDGS(0.036)ET(0.964)PQLFTVLPEKR;IEEAMDGS(0.001)ET(0.999)PQLFTVLPEKR;IEEAMDGS(0.178)ET(0.822)PQLFTVLPEKR;IEEAMDGS(0.011)ET(0.989)PQLFTVLPEKR;IEEAMDGS(0.008)ET(0.992)PQLFTVLPEKR ;;;; 151.85 1.57E-06 353979000 8706.4 8603.43 9087.2 9890.7 10199.5 13931.8 10803.5 10916.4 11107.3 9585.4 TRUE FALSE FALSE 8017.279253 9347.072153 9423.979626 9849.774904 10077.87762 11042.18764 11106.61713 14244.76011 9888.856979 9918.491937 0.808316355 0.942388441 0.950142389 0.993071827 1.016069549 1.113292999 1.119788896 1.436182052 0.997012151 1 13.27590507 -1.000000012 0.50647717 0.912392882 18.0597573 0.854136174 0.059919608 30.1867845 0.284998286 0.015078962 555.791262 0.099999997 1.000000012 17.14736441 IEEDFPHIR ddPTM_HeLa_Curcumin_4h_R1 1 IEEDFPHIR 9 0 Q9NTI5-2;Q9NTI5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 0 0 128.86 0.00070325 0 1865.6 1427.1 2073 2126.3 1964.1 2579.5 1950.3 1295.2 2262.6 2093.9 FALSE FALSE TRUE 1717.935791 1550.452165 2149.827204 2117.501934 1940.67939 2044.482623 2005.020169 1690.100518 2014.398441 2166.662869 0.792894832 0.715594561 0.992229679 0.977310298 0.89569975 0.943609018 0.925395546 0.78004776 0.929723987 1 11.08125897 -9.596376921 1.430880195 0.999147429 0.871283098 0.115508065 0.08800937 0.528242517 1.960964455 0.063308626 0.015094628 2.53E-10 9.596376921 -0.127864331 IEEDRCS(ph)NSADITGPSFIR ddPTM_HeLa_Curcumin_4h_R1 1 IEEDRCSNSADITGPSFIR 19 1 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 0 IEEDRCS(0.973)NS(0.027)ADITGPSFIR 92.428 0.00073568 21115000 908.77 872.08 813.79 1139.5 1063.2 968.94 805.56 542.03 1006 691.55 TRUE FALSE FALSE 836.8398956 947.4587093 843.9497733 1134.785051 1050.522034 767.9709218 828.1618455 707.2924518 895.6443169 715.581311 1.169454656 1.324040601 1.179390462 1.58582265 1.468068014 1.073212659 1.157327382 0.988416607 1.25163179 1 9.482971899 -8.191466381 0.918423374 1.026881394 1.258899694 0.011833311 0.182999237 0.546044266 0.976351317 0.057352003 0.039228393 6.43E-09 8.191466381 0.2320183 SIDAVIATASAPPSSS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 2 SIDAVIATASAPPSSSPGR 19 0 Q9NR48-2;Q9NR48 Q9NR48-2 ASH1L Histone-lysine N-methyltransferase ASH1L 1 0 SIDAVIATAS(0.003)APPS(0.044)S(0.044)S(0.909)PGR;SIDAVIATASAPPS(0.006)S(0.135)S(0.859)PGR ; 297.55 7.26E-84 14591000 9158.2 7993.5 8470.9 8582.2 8030.3 8477.9 4497.1 1280.48 9923.2 7427.6 TRUE FALSE FALSE 8433.318806 8684.422522 8784.839006 8546.68913 7934.543917 6719.487974 4623.276523 1670.892457 8834.649787 7685.708547 1.097272783 1.129944294 1.143009646 1.11202358 1.032376373 0.874283475 0.601542004 0.217402527 1.149490607 1 12.90796255 -4.465640254 1.280957733 1.067140694 0.019427237 0.968423588 0.051147139 0.13951834 0.251595552 0.008958398 0.172673735 3.42E-05 4.465640254 -1.047713457 down IEEEEQEPEPPEPFEYIDD ddPTM_HeLa_Curcumin_4h_R1 3 IEEEEQEPEPPEPFEYIDD 19 0 A0A087WW66;Q99460-2;Q99460 A0A087WW66 PSMD1 26S proteasome non-ATPase regulatory subunit 1 0 0 ;; ;; 168.31 5.90E-05 106137000 26974 21692.2 22271.2 23395.8 23819.6 28042.3 21732.5 19554.2 24676.1 21947.2 FALSE FALSE TRUE 24838.97944 23567.17711 23096.59026 23298.99438 23535.56683 22226.01088 22342.25546 25516.18556 21969.19357 22709.86357 1.093752913 1.037750713 1.017029019 1.025941627 1.036358794 0.978694161 0.983812844 1.123572825 0.967385537 1 14.47103142 -6.98072294 13.38408277 1.045401752 1.023989164 0 0.049268274 3.7674888 2607.650826 0.007924929 0.010396242 1.05E-07 6.98072294 -0.021412588 IEEELGS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 IEEELGSK 8 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 1 0 IEEELGS(1)K 115.7 0.0096178 6199100 2255.4 1858.1 2222.3 2480.8 2475.6 3134.1 2461 2172.1 2476.5 2231.6 TRUE FALSE FALSE 2076.88271 2018.705884 2304.660393 2470.535107 2446.080087 2484.052331 2530.049037 2834.363291 2204.834146 2309.147934 0.899415182 0.874221116 0.998056625 1.069890357 1.059299862 1.075744128 1.095663469 1.227449853 0.954825853 1 11.17314489 -5.178290573 0.667661146 0.947384428 1.212728081 0.754509728 0.048678472 0.597862351 0.348892034 0.011088084 0.095934827 6.63E-06 5.178290573 0.265343653 IEEELGSK ddPTM_HeLa_Curcumin_4h_R1 2 IEEELGSK 8 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 0 ; ; 122.19 0.0024887 117768000 8473.5 5713.8 7326 7496.8 6424.2 9296.2 8549 9251.4 7881.9 6829 FALSE FALSE TRUE 7802.813534 6207.675412 7597.508005 7465.780228 6347.595611 7368.06333 8788.861932 12072.10927 7017.27529 7066.307242 1.10422789 0.878489315 1.075173743 1.056532072 0.898290351 1.042703505 1.243770138 1.708404243 0.993061163 1 12.78674076 -4.304059999 2.113018391 1.028940843 1.858182102 0.899248515 0.071528874 0.143160399 0.75359598 0.010638307 0.216954856 4.97E-05 4.304059999 0.829241259 IEEELGSK(ac)AK ddPTM_HeLa_Curcumin_4h_R1 1 IEEELGSKAK 10 1 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 1 IEEELGSK(1)AK 194.94 2.34E-20 4265500 2216.3 1567.9 2220.1 2025.5 1927.7 2897.5 2087.9 2260.2 2466.6 1980.1 FALSE TRUE FALSE 2040.877516 1703.42229 2302.378859 2017.119018 1904.713437 2296.525838 2146.480855 2949.324575 2196.020151 2048.908328 0.996080444 0.831380432 1.12371004 0.984484757 0.929623552 1.120853387 1.047621714 1.439461461 1.0718001 1 11.00063972 -1.484462487 1.052903541 0.991708337 199.9999999 0.710528991 0.082371701 245.652975 0.786184609 0.010669304 117398.8299 0.032774609 1.484462487 199.0082916 IEEVLSPEGS(ph)PSKSPSK ddPTM_HeLa_Curcumin_4h_R1 1 IEEVLSPEGSPSKSPSK 17 1 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 0 IEEVLSPEGS(0.852)PS(0.029)KS(0.117)PS(0.002)K 174.52 0.00026148 20439000 1941.7 1587.6 1960.5 1702.4 2042.4 2043.1 1736.4 2032.5 1618.6 1604.4 TRUE FALSE FALSE 1788.012396 1724.82507 2033.157855 1695.35592 2018.045714 1619.33803 1785.118711 2652.199894 1441.04363 1660.152781 1.077016776 1.038955625 1.224681173 1.021204759 1.215578312 0.975415063 1.075273753 1.597563745 0.868018683 1 10.6971003 -4.262338816 6.038720447 1.058088934 1.611579224 0.724082607 0.100492603 0.04083841 7.27581675 0.010916191 0.092520264 5.47E-05 4.262338816 0.55349029 IEEVLSPEGS(ph)PSKSPSKK ddPTM_HeLa_Curcumin_4h_R1 1 IEEVLSPEGSPSKSPSKK 18 2 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 0 IEEVLS(0.008)PEGS(0.493)PS(0.102)KS(0.368)PS(0.03)KK 66.436 0.012605 17751000 1108.7 1220.7 1348.4 1133.3 1350.1 1205.6 845.92 1349.9 1098.7 845.76 TRUE FALSE FALSE 1020.945225 1326.211869 1398.37289 1128.610705 1334.000939 955.5449701 869.6542385 1761.478296 978.1753588 875.150097 1.166594426 1.515410754 1.597866349 1.289619585 1.524311023 1.091864097 0.993720096 2.012772782 1.117722962 1 9.773386665 -7.497076228 2.898502936 1.065708423 1.405865937 0.245280421 0.269471167 0.260156135 4.332148003 0.047517396 0.051963884 3.18E-08 7.497076228 0.340157514 IEEVLSPEGSPS(ph)KSPSKK ddPTM_HeLa_Curcumin_4h_R1 1 IEEVLSPEGSPSKSPSKK 18 2 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 0 IEEVLSPEGS(0.002)PS(0.407)KS(0.33)PS(0.26)KK 70.315 0.01015 32137000 1356.6 901.72 957.35 1394.3 1152.4 1230.7 1190.7 1033.2 1121.2 948.86 TRUE FALSE FALSE 1249.223679 979.6606588 992.8302332 1388.530756 1138.658383 975.4389472 1224.107837 1348.217924 998.2071651 981.8328144 1.272338488 0.997787652 1.011200908 1.414223212 1.159727365 0.993487825 1.24675792 1.373164457 1.016677331 1 9.939333574 -6.306780893 24.99673658 1.111973795 1.22011481 0.254253694 0.136875372 787.6406732 434224.0508 0.023902013 0.036511035 4.93E-07 6.306780893 0.108141015 IEEVLSPEGSPSKS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 IEEVLSPEGSPSKSPSK 17 1 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 0 IEEVLSPEGS(0.022)PS(0.01)KS(0.738)PS(0.23)K 132.25 0.0033027 26658000 2897.3 2545.1 2909 2941.9 3533.5 2733.6 3005.6 2770.4 2230.1 2558 TRUE FALSE FALSE 2667.975648 2765.087103 3016.810099 2929.727197 3491.36532 2166.620546 3089.929047 3615.082207 1985.463609 2646.89031 1.007966079 1.044654965 1.139756373 1.106856293 1.319044204 0.818553205 1.167380845 1.365784669 0.750111783 1 11.37008269 -1 0.295602444 1.002379289 3.219126304 0.301917402 0.154088931 47.39370773 0.606181675 0.049492088 56.04145557 0.1 1 2.216747015 IEEVPELPLVVEDK ddPTM_HeLa_Curcumin_4h_R1 2 IEEVPELPLVVEDK 14 0 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 0 ; ; 203.11 4.66E-08 3870700 2496.4 2069.47 2473.2 2440.5 3033 2864.1 2430.6 2433.4 2082.9 1870.68 FALSE FALSE TRUE 2298.807306 2248.345765 2564.858968 2430.401858 2996.833456 2270.053375 2498.796094 3175.332458 1854.411081 1935.685991 1.187593089 1.161524016 1.325038761 1.255576508 1.548202276 1.172738443 1.290909841 1.64041713 0.958012348 1 10.91862922 -1.000000009 0.068428015 0.596585287 2.837303897 0.642544609 0.121645942 115.0443218 0.588268469 3.520966857 25.08149099 0.099999998 1.000000009 2.240718609 IEEVPELPLVVEDKVEGYKK ddPTM_HeLa_Curcumin_4h_R1 1 IEEVPELPLVVEDKVEGYKK 20 2 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 0 93.738 0.00035496 12432000 4349 3429.1 3492.1 4001.4 3350.3 4597.6 3362.9 3459.5 3976.6 3174.2 FALSE FALSE TRUE 4004.772061 3725.496124 3621.520298 3984.843267 3310.349861 3644.005934 3457.253923 4514.285624 3540.376929 3284.503214 1.219293086 1.134264722 1.102608237 1.213225565 1.007869271 1.109454215 1.052595689 1.374419609 1.077903323 1 11.68145946 -9.506403427 1.249150942 0.999805571 1.150718339 0.157258566 0.09901988 0.505059956 1.40766827 0.064974051 0.015626714 3.12E-10 9.506403427 0.150912768 IEGEMQVPDVDIR ddPTM_HeLa_Curcumin_4h_R1 1 IEGEMQVPDVDIR 13 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 234.65 3.40E-19 13136000 1960.5 2091.4 1705.5 2064.3 2090.2 2616.2 1711.4 1647.6 2195.9 1798.7 FALSE FALSE TRUE 1805.324356 2272.171297 1768.70733 2055.758474 2065.27573 2073.570629 1759.417278 2149.945655 1955.015264 1861.204691 0.969976255 1.220806775 0.950302424 1.104531105 1.109644597 1.114101334 0.945311006 1.155136598 1.050403147 1 10.86202101 IEHAPS(ph)PSSGGTLK ddPTM_HeLa_Curcumin_4h_R1 1 IEHAPSPSSGGTLK 14 0 Q14004-2;Q14004;A0A2R8Y7W5;A0A2R8Y4Z0;A0A2R8Y7Y0;A0A2R8YCQ1;A0A2R8YD28 Q14004-2 CDK13 Cyclin-dependent kinase 13 1 0 IEHAPS(0.981)PS(0.016)S(0.003)GGTLK 75.239 0.011933 8011100 2543.1 2164.1 2214.5 2254.9 3024.1 2533 2073 1625.4 2797.9 1903.5 TRUE FALSE FALSE 2341.810952 2351.155161 2296.571318 2245.569821 2988.039583 2007.627247 2131.162801 2120.976978 2490.97737 1969.646483 1.188949881 1.193693986 1.165981478 1.140087747 1.517043595 1.019283036 1.082002694 1.076831297 1.264682465 1 10.943721 -9.176779557 0.824598811 0.994807866 1.176248011 0 0.150940203 0.850180588 0.997956003 0.097811844 0.024969589 6.66E-10 9.176779557 0.181440146 IEHSFWR ddPTM_HeLa_Curcumin_4h_R1 1 IEHSFWR 7 0 Q16531;Q16531-2 Q16531 DDB1 DNA damage-binding protein 1 0 0 162.31 0.0061282 7192600 5761.1 3268.3 4975.7 4004.7 5444.1 7195.3 5160.9 5422.8 4275.9 4503.4 FALSE FALSE TRUE 5305.102856 3550.797289 5160.103819 3988.129613 5379.182663 5702.913672 5305.700964 7076.186756 3806.844468 4659.892815 1.138460275 0.761991194 1.107343886 0.855841491 1.154357595 1.223829367 1.138588627 1.51852994 0.816938204 1 12.18608106 -1.000018006 0.74043756 1.036740464 79.35871237 0.546630835 0.143213475 190.9703482 0.804895017 0.020415893 24942.81053 0.099995854 1.000018006 78.32197191 IENHEGVR ddPTM_HeLa_Curcumin_4h_R1 4 IENHEGVR 8 0 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BQ34;H3BR70 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ;;; ;;; 126.31 0.00057991 105734200 24241.4 42679.9 16862 16575.4 13285.1 21375.4 14962.1 13007.2 14876.1 20159.2 FALSE FALSE TRUE 22322.66761 46368.96038 17486.92055 16506.81539 13126.68386 16941.90109 15381.89626 16973.0354 13244.22905 20859.7307 1.070132109 2.222893528 0.838309986 0.791324472 0.629283477 0.812182158 0.737396685 0.813674714 0.634918506 1 14.34843291 -6.546022299 24.99931405 1.142672806 0.758003445 0.247540945 0.383985326 278.5298196 300862.4992 0.057131552 0.080798756 2.84E-07 6.546022299 -0.384669361 IEPIPGES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 IEPIPGESPK 10 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 0 IEPIPGES(1)PK;IEPIPGES(1)PK;IEPIPGES(1)PK;IEPIPGES(1)PK ;;; 138.42 0.0017283 117712000 25104.8 21434.7 23989.8 24560.7 23333.6 23862.2 21199.7 21352.8 26338.9 22762.7 TRUE FALSE FALSE 23117.72859 23287.41996 24878.88309 24459.07433 23055.36206 18912.91074 21794.50653 27863.17042 23449.58857 23553.70213 0.981490233 0.988694679 1.056262109 1.038438637 0.978842389 0.802969768 0.925311291 1.182963522 0.995579737 1 14.52366622 -5.519328556 24.9522092 0.999584967 0.953404776 0.022950404 0.090167229 360.0808184 2530792.448 0.012639364 0.025696908 3.02E-06 5.519328556 -0.046180192 IEPIPGESPK ddPTM_HeLa_Curcumin_4h_R1 1 IEPIPGESPK 10 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 0 0 138.4 0.00030875 1901800 1497.4 1306.3 1223.7 1412 1320.6 1786.6 1513.5 1306.6 1687.7 1449.3 FALSE FALSE TRUE 1378.87921 1419.210751 1269.051398 1406.157518 1304.852708 1416.039021 1555.964737 1704.976325 1502.563532 1499.663067 0.919459337 0.946353072 0.846224346 0.937648962 0.870097248 0.94423811 1.037542879 1.136906257 1.001934078 1 10.55042269 -4.497705146 2.499414849 0.942501119 1.140014175 0.654621225 0.047055216 0.186916813 1.961583361 0.007447047 0.0622373 3.18E-05 4.497705146 0.197513056 IES(ph)DEEEDFENVGK ddPTM_HeLa_Curcumin_4h_R1 4 IESDEEEDFENVGK 14 0 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 0 IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK;IES(1)DEEEDFENVGK ;;; 274.38 6.62E-63 152147000 24136.5 20006.6 23093.1 20920 22951.5 25197.3 21412.5 19072.7 21969.9 20006.2 TRUE FALSE FALSE 22226.07056 21735.88136 23948.9506 20833.43858 22677.81835 19971.09595 22013.27712 24887.87843 19559.85694 20701.41396 1.073649877 1.049970857 1.156875112 1.006377565 1.095471952 0.964721346 1.063370703 1.202230847 0.944856084 1 14.33744169 -9.156182073 0.686249262 0.994204761 1.073355727 0.258042261 0.066611236 1.300988597 0.991124327 0.059812827 0.013223061 6.98E-10 9.156182073 0.079150966 IES(ph)DVQEPTEPEDDLDIMLGNK ddPTM_HeLa_Curcumin_4h_R1 2 IESDVQEPTEPEDDLDIMLGNK 22 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 0 IES(1)DVQEPTEPEDDLDIMLGNK;IES(1)DVQEPTEPEDDLDIMLGNK ; 133.98 5.90E-06 3819900 3089.98 2333.62 2575.51 2766.96 3655.47 4746.5 4468.2 2188.86 2742.09 2601.18 TRUE FALSE FALSE 2845.404822 2535.327714 2670.960666 2755.511053 3611.880908 3762.022396 4593.565666 2856.233338 2441.289587 2691.570811 1.05715399 0.941950962 0.992342707 1.023755734 1.341923048 1.397705154 1.706648641 1.061177111 0.907012952 1 11.39423267 -5.707588088 3.699486637 1.016354952 1.413674406 0.608462637 0.151948685 0.105167634 2.933660048 0.019678645 0.040166255 1.96E-06 5.707588088 0.397319454 IES(ph)PERTDVYVEQK ddPTM_HeLa_Curcumin_4h_R1 1 IESPERTDVYVEQK 14 1 A0A0C4DFQ2;Q8NCN2 A0A0C4DFQ2 ZBTB34 Zinc finger and BTB domain-containing protein 34 1 0 IES(0.583)PERT(0.416)DVYVEQK 63.546 0.019036 7562200 1406.6 1064.7 1449 1174.4 1341.6 1350.1 1078 532.59 1304.5 1186.9 TRUE FALSE FALSE 1295.266126 1156.727924 1502.701215 1169.540644 1325.602296 1070.074041 1108.245779 694.9742393 1161.399614 1228.144687 1.054652713 0.941849878 1.223553895 0.95228246 1.079353525 0.871293141 0.902373955 0.565873261 0.945653738 1 10.26226482 -3.886650674 1.001735225 1.031929391 4.64E-16 0.70617998 0.087568961 1.243859699 0.582692108 0.011434033 1.646625594 0.000129822 3.886650674 -1.031929391 IESDVQEPT(ph)EPEDDLDIMLGNK ddPTM_HeLa_Curcumin_4h_R1 5 IESDVQEPTEPEDDLDIMLGNK 22 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 0 IES(0.321)DVQEPT(0.679)EPEDDLDIMLGNK;IES(0.079)DVQEPT(0.921)EPEDDLDIMLGNK;IES(0.037)DVQEPT(0.963)EPEDDLDIMLGNK;IESDVQEPT(1)EPEDDLDIMLGNK;IES(0.001)DVQEPT(0.999)EPEDDLDIMLGNK ;;;; 128.19 1.42E-05 73842300 20262.2 16956.6 19442.3 21299.4 21325 32064.3 35728.2 23041.8 23364 19794.5 TRUE FALSE FALSE 18658.42549 18422.25295 20162.84874 21211.26873 21070.7133 25413.80274 36730.63713 30067.13875 20801.02765 20482.3574 0.910951075 0.89942054 0.984400787 1.035587277 1.028725009 1.240765516 1.793281721 1.467953037 1.01555828 1 14.32209415 -5.012329501 2.766991451 0.964153841 1.63096867 0.884326155 0.092353866 0.053863538 0.820691602 0.012333192 0.041689767 9.72E-06 5.012329501 0.666814829 IESDVQEPT(ph)EPEDDLDIMLGNKK ddPTM_HeLa_Curcumin_4h_R1 3 IESDVQEPTEPEDDLDIMLGNKK 23 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 0 IES(0.004)DVQEPT(0.996)EPEDDLDIMLGNKK;IES(0.002)DVQEPT(0.998)EPEDDLDIMLGNKK;IES(0.231)DVQEPT(0.769)EPEDDLDIMLGNKK ;; 86.997 0.00022815 88519000 7827 5872 6463.2 7198.2 7104.3 11466.6 12262.4 7140.4 8379 6710.3 TRUE FALSE FALSE 7207.484691 6379.549515 6702.731878 7168.415756 7019.585862 9088.297905 12606.44994 9317.47509 7459.844663 6943.482426 1.038021593 0.91878241 0.965327118 1.032394887 1.010960413 1.308896221 1.815580305 1.341902308 1.074366464 1 12.7614437 -5.06121592 3.487228824 1.007974904 1.581042543 0.798142772 0.11599532 0.061378892 1.4672776 0.014178686 0.042053594 8.69E-06 5.06121592 0.573067639 IESPKLER ddPTM_HeLa_Curcumin_4h_R1 1 IESPKLER 8 1 A0A0A0MSM0;Q92598-2;Q92598-3;Q92598;Q92598-4;Q5TBM3 A0A0A0MSM0 HSPH1 Heat shock protein 105 kDa 0 0 95.815 0.015093 8598500 7480.3 6472.5 6828.7 6821.3 7065.1 7793.3 5757.6 5118.2 8070.8 7198.6 FALSE FALSE TRUE 6888.226362 7031.954059 7081.777629 6793.075268 6980.853297 6176.881731 5919.14276 6678.715619 7185.453432 7448.750814 0.924749201 0.944044744 0.950733594 0.9119751 0.937184431 0.829250687 0.79464905 0.896622237 0.964652143 1 12.86278278 -1 0.118953298 1.033492162 0.390544825 0.598237046 0.03727365 43.3827794 0.355661796 0.172876062 4.636098207 0.1 1 -0.642947337 IET(ph)DEEESCDNAHGDANQPAR ddPTM_HeLa_Curcumin_4h_R1 1 IETDEEESCDNAHGDANQPAR 21 0 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 0 IET(0.857)DEEES(0.143)CDNAHGDANQPAR 182.62 5.03E-10 97899000 2673 2288.7 2651.6 2339.8 2648 2946.2 2481.7 2126.8 2646.3 2425.5 TRUE FALSE FALSE 2461.429229 2486.52503 2749.870629 2330.118528 2616.424329 2335.124909 2551.329823 2775.251529 2356.007511 2509.785944 0.980732733 0.990731913 1.095659427 0.928413251 1.042489036 0.930407995 1.016552758 1.105772202 0.938728466 1 11.29334861 -4.301182931 3.97972839 0.993653869 1.112031434 0.332005782 0.049384601 0.160994249 4.938699131 0.005653265 0.050244443 5.00E-05 4.301182931 0.118377565 IETIAASST(ph)PTPIR ddPTM_HeLa_Curcumin_4h_R1 1 IETIAASSTPTPIR 14 0 Q96P47;Q96P47-2;Q96P47-4;Q96P47-5;H7C5G0;H7C4U6;E7ESL9;Q96P47-3;Q96P47-6 Q96P47 AGAP3 "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3" 1 0 IETIAAS(0.003)S(0.019)T(0.976)PT(0.002)PIR 202.61 1.67E-08 8462700 1875.9 1635.3 1999.3 2227.5 2519.5 2009 1541.9 700.36 1843.7 1140.5 TRUE FALSE FALSE 1727.420536 1776.648045 2073.395817 2218.283195 2489.456608 1592.310754 1585.161564 913.8965399 1641.450723 1180.13229 1.463751607 1.505465159 1.75691813 1.87969028 2.109472496 1.349264627 1.343206671 0.774401775 1.390904 1 10.20473288 -8.694994369 0.778347719 1.021011021 1.552705857 0.082955026 0.358367363 0.668596899 0.803701334 0.188140339 0.077775251 2.02E-09 8.694994369 0.531694836 IETIEVMEDR ddPTM_HeLa_Curcumin_4h_R1 5 IETIEVMEDR 10 0 P51991;P51991-2 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 0 ;;;; ;;;; 169.65 7.56E-06 86943700 13354.2 10893.6 12519 11944.6 12673.75 14751.7 11906.9 11770.4 12994.1 10819.9 FALSE FALSE TRUE 12297.20098 11835.19424 12982.96515 11895.17641 12522.62381 11692.03113 12240.97557 15359.14078 11568.67974 11195.89072 1.098367364 1.057101622 1.159618781 1.062459139 1.11850179 1.04431451 1.093345396 1.371855189 1.033296951 1 13.45068169 -4.261731439 3.839145972 1.062464095 1.402432024 0.807135349 0.043585221 0.091628741 2.635045049 0.007192073 0.087385926 5.47E-05 4.261731439 0.339967928 ASS(ph)PAQCVTPVQTVV ddPTM_HeLa_Curcumin_4h_R1 1 ASSPAQCVTPVQTVV 15 0 Q13614;Q13614-2 Q13614 MTMR2 Myotubularin-related protein 2 1 0 AS(0.147)S(0.853)PAQCVTPVQTVV 162.7 0.00027647 38599000 2469.4 2407.3 2488.1 2495.8 2283.9 1946.4 1781.9 696.69 2572.4 2248.1 TRUE FALSE FALSE 2273.944384 2615.376285 2580.311175 2485.473041 2256.665984 1542.6947 1831.895318 909.1075738 2290.214156 2326.221308 0.977527107 1.124302437 1.109228587 1.068459408 0.970099438 0.66317624 0.787498297 0.390808721 0.984521184 1 11.18377264 -4.465466942 0.917420263 1.015670144 0.240898894 0.8279042 0.090696484 0.508831101 0.392844612 0.014687846 0.364044244 3.42E-05 4.465466942 -0.774771249 down IEVEK(ac)PFAIAK ddPTM_HeLa_Curcumin_4h_R1 1 IEVEKPFAIAK 11 1 P23284 P23284 PPIB Peptidyl-prolyl cis-trans isomerase B 0 1 IEVEK(1)PFAIAK 193.52 3.02E-16 824580 324.14 284.2 386.99 260.94 620.06 697.26 603.22 546.8 576.69 294.69 FALSE TRUE FALSE 298.483977 308.7649816 401.3321898 259.8602994 612.6661895 552.6404163 620.1447297 713.5168028 513.4285498 304.9304556 0.978859184 1.012575084 1.316143345 0.852195295 2.009199732 1.812349033 2.033725128 2.339932892 1.683756215 1 8.252336439 -5.755258665 24.99994471 1.010227589 2.030835574 0.723514543 0.267777466 30.5109934 123410.5641 0.022936367 0.044965291 1.76E-06 5.755258665 1.020607984 AVGPTAEADK(ac)SAAEK ddPTM_HeLa_Curcumin_4h_R1 2 AVGPTAEADKSAAEK 15 1 D6REL4;E7EQZ7;Q13123 D6REL4 IK Protein Red 0 1 ; AVGPTAEADK(1)SAAEK;AVGPTAEADK(1)SAAEK 257.02 1.32E-61 8606000 3425.1 3056.5 2563.2 2683.1 3026.3 4257.5 4727.2 7628.2 3708.9 3051.6 FALSE TRUE FALSE 3153.999721 3320.690241 2658.194447 2671.998043 2990.213349 3374.446508 4859.832509 9954.003064 3302.042949 3157.642873 0.998846243 1.051635785 0.841828716 0.846200204 0.946976422 1.068659961 1.539069713 3.152352392 1.045730338 1 11.6246323 -4.201729972 1.872447809 0.976923943 4.069830509 0.98808522 0.072104327 0.074722361 0.235609741 0.011002954 0.422331887 6.28E-05 4.201729972 3.092906566 up IEVIEIMTDR ddPTM_HeLa_Curcumin_4h_R1 3 IEVIEIMTDR 10 0 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8VZ49;A0A2R8Y4L2;H0YH80;Q32P51;F8VYN5 F8W6I7 HNRNPA1;HNRNPA1L2 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;Heterogeneous nuclear ribonucleoprotein A1-like 2" 0 0 ;; ;; 166.34 0.0047044 80654940 4070.15 3317.36 3765.861 3438.22 4106.9 4962.56 4001.78 3349.481 3673.8 3714.3 FALSE FALSE TRUE 3747.993333 3604.097817 3905.427121 3423.993557 4057.9279 3933.269116 4114.059177 4370.722338 3270.793331 3843.371649 0.975183686 0.937743769 1.016146103 0.890882764 1.055825008 1.023390261 1.070429704 1.137210433 0.851021871 1 11.90815677 -4.529454299 1.022517673 0.98160808 1.174116777 0.497424922 0.057648409 0.610181235 0.65970281 0.005841288 0.114952391 2.95E-05 4.529454299 0.192508697 IEVLDS(ph)PASK ddPTM_HeLa_Curcumin_4h_R1 3 IEVLDSPASK 10 0 Q8N5I9 Q8N5I9 C12orf45 Uncharacterized protein C12orf45 1 0 IEVLDS(0.936)PAS(0.064)K;IEVLDS(0.919)PAS(0.081)K;IEVLDS(0.998)PAS(0.002)K ;; 145.23 0.001148 100347000 18993.2 16686.2 18269.7 17496.6 18624.3 23432.7 18962.7 7803.1 18630.5 15454.8 TRUE FALSE FALSE 17489.86818 18128.48078 18946.79115 17424.20371 18402.21739 18572.49388 19494.74233 10182.22927 16586.78076 15991.85315 1.093673636 1.133607257 1.18477771 1.089567516 1.15072451 1.161372213 1.219042105 0.63671353 1.037201918 1 13.96504951 -1.334296331 14.79792037 1.068009864 0.003224141 0 0.15780402 0 0 0.019169043 0 0.046313081 1.334296331 -1.064785723 IEVLPVDTGAGGYSGNSGS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 IEVLPVDTGAGGYSGNSGSPK 21 0 X6RAB3;Q92738;Q92738-2 X6RAB3 USP6NL USP6 N-terminal-like protein 1 0 IEVLPVDTGAGGYSGNSGS(1)PK;IEVLPVDTGAGGYS(0.009)GNS(0.168)GS(0.823)PK ; 222.54 4.11E-23 32845000 22475 16735.3 19356 19782.3 19392.5 24415 16987.5 12769.7 24086 17606.8 TRUE FALSE FALSE 20696.08003 18181.82476 20073.35039 19700.44608 19161.2571 19351.05379 17464.12353 16663.12275 21443.82606 18218.63499 1.13598412 0.997979529 1.101803203 1.081334913 1.051739448 1.06215717 0.958585731 0.914619715 1.177027043 1 14.15312725 -4.665792427 3.020604493 1.06409243 0.920098502 0.5197528 0.0533207 0.163334707 2.840209213 0.007438217 0.036406753 2.16E-05 4.665792427 -0.143993928 IEWLESHQDADIEDFK ddPTM_HeLa_Curcumin_4h_R1 2 IEWLESHQDADIEDFK 16 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 0 ; ; 128.64 0.00038051 35667000 12571.5 11019.1 13836.3 13356.9 15159.7 14750.9 9842.2 6923.9 11285.4 10190 FALSE FALSE TRUE 11576.45251 11971.5419 14349.08545 13301.63269 14978.93048 11691.39706 10118.34564 9034.965236 10047.41985 10544.10174 1.097907891 1.135378072 1.360863713 1.261523553 1.42059806 1.108809204 0.959621397 0.856873867 0.952894813 1 13.36414858 -2.9125675 13.70330666 1.09875229 1.128157229 0 0.175816347 0 0 0.02454376 0 0.001223017 2.9125675 0.029404939 IEYAKPTR ddPTM_HeLa_Curcumin_4h_R1 1 IEYAKPTR 8 1 P14866;M0QXS5;A0A3B3ITJ4;P14866-2;B4DVF8;M0R1W6 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 0 82.426 0.01846 5117400 4261.2 3191.2 3848.5 3866.9 3938.2 4866.9 3813.8 3131.7 3954.2 3816.6 FALSE FALSE TRUE 3923.921524 3467.033108 3991.128795 3850.899792 3891.239537 3857.450079 3920.804964 4086.540913 3520.434153 3949.226566 0.993592406 0.877901799 1.010610237 0.975102271 0.985316864 0.976760896 0.992803248 1.034769934 0.891423699 1 11.94735442 -7.496805153 24.95713372 0.997173148 0.977567275 0 0.050780944 660.6379189 632357.1625 0.006508865 0.0070234 3.19E-08 7.496805153 -0.019605873 IEYNDQNDGSCDVK ddPTM_HeLa_Curcumin_4h_R1 1 IEYNDQNDGSCDVK 14 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 219.89 3.84E-13 10531000 1918.4 1489.4 2158.5 1845.7 1948.1 2372.8 1579 1670.8 1484.4 1666.4 FALSE FALSE TRUE 1766.556616 1618.137099 2238.495909 1838.062982 1924.87018 1880.654533 1623.30249 2180.219229 1321.565034 1724.307276 1.02450221 0.938427345 1.298200118 1.06597183 1.11631506 1.090672503 0.941422978 1.264402963 0.766432441 1 10.75180117 IFDFDDDGTLNREDLSR ddPTM_HeLa_Curcumin_4h_R1 1 IFDFDDDGTLNREDLSR 17 1 Q99828;Q99828-2 Q99828 CIB1 Calcium and integrin-binding protein 1 0 0 106.42 0.0012175 4754900 1033.1 1132.3 907.58 1068 991.41 918.31 656.08 619.55 1206.9 1155.7 FALSE FALSE TRUE 951.3290449 1230.170967 941.2157132 1063.580899 979.5880833 727.8421545 674.4878391 808.4479429 1074.50609 1195.860489 0.795518418 1.028691037 0.787061469 0.889385433 0.819149133 0.60863467 0.564018834 0.676038677 0.898521274 1 10.22383338 -5.387986269 2.656615762 0.900988119 0.606886692 0.735843863 0.075846298 0.12730236 1.73126249 0.013419113 0.034201848 4.09E-06 5.387986269 -0.294101427 IFDIDEAEEGVK ddPTM_HeLa_Curcumin_4h_R1 1 IFDIDEAEEGVK 12 0 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 0 0 155.26 0.0029434 3034400 1687 1258.6 1715.8 1435 2018.6 2165.2 1813.5 1726.5 1745.3 1523.1 FALSE FALSE TRUE 1553.47217 1367.387776 1779.389057 1429.06235 1994.529513 1716.113113 1864.381929 2252.901902 1553.844957 1576.027612 0.985688422 0.867616637 1.12903419 0.906749564 1.26554224 1.088885182 1.182962732 1.429481238 0.985924958 1 10.6220771 -1 0.447071969 0.98497047 10.60265682 0.659821184 0.095613526 30.82007162 0.334604802 0.018669907 272.4183764 0.1 1 9.617686347 IFDIDEAEEGVKDLK ddPTM_HeLa_Curcumin_4h_R1 2 IFDIDEAEEGVKDLK 15 1 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 0 0 ; ; 145.1 0.0004235 26401000 4157.8 2745.2 3076.9 3471.2 2944.3 4531.8 3296.2 3264.6 4216.3 3557.6 FALSE FALSE TRUE 3828.705743 2982.482856 3190.932621 3456.837094 2909.191145 3591.853596 3388.682501 4259.961512 3753.782439 3681.226335 1.040062575 0.810187308 0.866812396 0.939044976 0.790277717 0.97572202 0.920530875 1.157212604 1.019709764 1 11.84597074 -7.306613718 24.97345976 1.01891845 0.918144205 0.175377317 0.096102317 505.823526 279630.2569 0.015919438 0.018204626 4.94E-08 7.306613718 -0.100774245 IFDLGS(ph)DNEEVVAGPAPAHAK ddPTM_HeLa_Curcumin_4h_R1 2 IFDLGSDNEEVVAGPAPAHAK 21 0 A0A096LNM2;Q969U6-2;Q969U6 A0A096LNM2 FBXW5 F-box/WD repeat-containing protein 5 1 0 IFDLGS(1)DNEEVVAGPAPAHAK;IFDLGS(1)DNEEVVAGPAPAHAK ; 136.61 1.31E-05 30624000 7339.1 5732.4 6654.7 6538.4 6883.8 7489.1 3964.4 2867.5 6772.3 6310.1 TRUE FALSE FALSE 6758.202491 6227.883113 6901.329036 6511.345833 6801.715181 5935.77624 4075.630394 3741.78755 6029.395633 6529.375505 1.035045769 0.953825233 1.056966172 0.997238684 1.041709912 0.909087896 0.624199112 0.573069744 0.923426081 1 12.6727293 -4.813207605 2.729467342 1.014876823 0.574509696 0.940354235 0.039949856 0.02701886 0.396503126 0.003778682 0.015992427 1.54E-05 4.813207605 -0.440367127 IFFAGDTIPK ddPTM_HeLa_Curcumin_4h_R1 2 IFFAGDTIPK 10 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 168.27 2.28E-12 2870900 1654.9 1111.57 2320.44 1285.41 1854.61 2961.76 2244.2 2178.95 1317.82 862.87 FALSE FALSE TRUE 1523.912919 1207.649158 2406.437548 1280.091314 1832.494987 2347.45759 2307.166212 2843.301824 1173.258443 892.8546683 1.706787199 1.352570805 2.695217523 1.433706245 2.052400074 2.629159788 2.584033319 3.184506869 1.314053098 1 9.802281554 -1 0.145896203 0.785151209 8.967215282 0.716781339 0.37337062 24.93965478 0.237400854 0.836316837 43.10283211 0.1 1 8.182064073 up IFFDT(ph)DDDDDMPHSTSR ddPTM_HeLa_Curcumin_4h_R1 1 IFFDTDDDDDMPHSTSR 17 0 Q8NG27-3;Q8NG27 Q8NG27-3 PJA1 E3 ubiquitin-protein ligase Praja-1 1 0 IFFDT(1)DDDDDMPHSTSR 110.98 0.0010606 1143800 512.38 518.35 456.38 308.38 550.8 942.6 379.42 311.54 754.49 480.94 TRUE FALSE FALSE 471.8245823 563.1538643 473.2938443 307.1040053 544.2320697 747.0941347 390.065504 406.5271118 671.7243346 497.6526292 0.94810025 1.131620394 0.951052635 0.61710516 1.093598301 1.501236185 0.783810797 0.816889308 1.349785564 1 8.958995255 -4.322085659 0.004337045 1.137763356 0.82049407 0 0.252992094 2207764.331 1545.412099 54828.86782 58264.02072 4.76E-05 4.322085659 -0.317269285 IFIGTFK ddPTM_HeLa_Curcumin_4h_R1 2 IFIGTFK 7 0 P63162-2;J3KRY3;S4R3P3;J3QLE5;P14678-2;P63162;P14678;P14678-3 P63162-2 SNRPN;SNRPB Small nuclear ribonucleoprotein-associated protein N;Small nuclear ribonucleoprotein-associated proteins B and B 0 0 ; ; 110.63 0.013481 10717400 3895.5 2106.58 3593.1 2892.4 3260.8 4126.5 3575.1 3881.1 3214 2704.3 FALSE FALSE TRUE 3587.167064 2288.663388 3726.263447 2880.432015 3221.91709 3270.617385 3675.407684 5064.429524 2861.432241 2798.274224 1.281921205 0.817883883 1.331629122 1.029360164 1.151394335 1.168798025 1.313455148 1.809840323 1.022570346 1 11.45032163 -4.090313803 1.502711449 1.12018052 2.319823075 0.702380181 0.139964843 0.768329642 1.148312961 0.020805818 1.536658066 8.12E-05 4.090313803 1.199642555 IFRDGEEAGAYDGPR ddPTM_HeLa_Curcumin_4h_R1 3 IFRDGEEAGAYDGPR 15 1 H7BZJ3;P30101 H7BZJ3;P30101 PDIA3 Protein disulfide-isomerase A3 0 0 ;; ;; 155.57 0.00032311 82017000 11300.3 8085.1 8750.8 9939.1 8055.4 10968.9 7215.7 5829.1 11760.2 9945.9 FALSE FALSE TRUE 10405.86933 8783.940017 9075.112346 9897.974638 7959.344616 8693.826495 7418.153122 7606.365756 10470.13548 10291.51928 1.011111095 0.853512467 0.881804921 0.961760296 0.77338869 0.844756372 0.720802528 0.739090658 1.017355669 1 13.32916836 -5.599332311 0.42027694 1.014636864 0.666946918 0.768038548 0.051794683 0.653305921 0.160924787 0.016128785 0.096980062 2.52E-06 5.599332311 -0.347689947 IFREEQNGEDEDGGWR ddPTM_HeLa_Curcumin_4h_R1 3 IFREEQNGEDEDGGWR 16 1 Q6Y7W6-4;Q6Y7W6-5;Q6Y7W6;I1E4Y6;Q6Y7W6-3;E7ESB6;C9JHW1;C9JH78;C9IYH5 Q6Y7W6-4 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 0 0 ;; ;; 108.14 0.0015252 29164600 11898 9382.6 10733.5 11292.9 9819.2 10208.4 5145.5 2176.21 12630.9 11065.4 FALSE FALSE TRUE 10956.26075 10193.59014 11131.29295 11246.17297 9702.112453 8091.062768 5289.868882 2839.726411 11245.32187 11449.92183 0.956885201 0.890275959 0.972171961 0.982205219 0.847351851 0.706647861 0.462000436 0.248012734 0.982130886 1 13.48305013 -4.650982675 0.976907327 0.974506337 0.085328254 0.982866264 0.032021091 0.105825163 0.113826596 0.005521958 0.085237483 2.23E-05 4.650982675 -0.889178083 down IFSLS(ph)GTLETVR ddPTM_HeLa_Curcumin_4h_R1 1 IFSLSGTLETVR 12 0 B4DEM9;Q9Y2S7 B4DEM9 POLDIP2 Polymerase delta-interacting protein 2 1 0 IFS(0.001)LS(0.5)GT(0.5)LETVR 96.82 0.011078 13585000 1178.4 1247.3 1335.1 1176.4 1174.3 1959.7 1696.9 1635.3 1231.7 1233.8 TRUE FALSE FALSE 1085.128397 1355.111054 1384.57998 1171.532369 1160.297239 1553.23613 1744.510447 2133.895442 1096.585592 1276.674458 0.849964836 1.061438212 1.084520781 0.917643774 0.908843466 1.216626619 1.36644893 1.67144837 0.858939085 1 10.31817498 -4.586540046 1.199644713 0.945215751 1.787331072 0.887989641 0.082855178 0.224089734 0.388843431 0.013639493 0.201945155 2.59E-05 4.586540046 0.842115321 IFSLSGT(ph)LETVR ddPTM_HeLa_Curcumin_4h_R1 1 IFSLSGTLETVR 12 0 B4DEM9;Q9Y2S7 B4DEM9 POLDIP2 Polymerase delta-interacting protein 2 1 0 IFSLS(0.006)GT(0.99)LET(0.004)VR 148.89 0.0018161 19181000 1716.9 1270.1 1308.1 1657.6 1445.5 2771.5 1902.9 2012.5 1919.5 1441.4 TRUE FALSE FALSE 1581.005553 1379.881785 1356.579337 1650.74129 1428.263357 2196.659659 1956.290253 2626.101986 1708.935652 1491.488543 1.060018571 0.925170891 0.909547273 1.106774369 0.957609338 1.472796871 1.311636125 1.760725551 1.145792008 1 10.54253718 -4.528741435 0.898581947 1.009341378 1.918986137 0.787553143 0.120097658 0.441271413 0.343511775 0.016495015 0.356853642 2.96E-05 4.528741435 0.909644759 IFTSIGEDYDER ddPTM_HeLa_Curcumin_4h_R1 4 IFTSIGEDYDER 12 0 P35232;C9JZ20;E7ESE2;E9PCW0;C9JW96;P35232-2;D6RBK0 P35232 PHB Prohibitin 0 0 ;;; ;;; 292.68 1.40E-71 154386000 7403.5 6036.08 6705.2 7190.5 6326.78 7715.9 5273.7 4266.28 7949.6 6578.24 FALSE FALSE TRUE 6817.505163 6557.811859 6953.70061 7160.747616 6251.337281 6115.535364 5421.665829 5567.049132 7077.548769 6806.83335 1.001567809 0.963415956 1.021576444 1.051993967 0.91839141 0.898440589 0.796503389 0.817861823 1.039771125 1 12.73276807 -5.185003149 1.623299686 1.002023733 0.805385573 0.865912926 0.031413412 0.089947511 0.441012071 0.004087175 0.015740309 6.53E-06 5.185003149 -0.19663816 IFTT(ph)PLTPSQYYSGSK ddPTM_HeLa_Curcumin_4h_R1 1 IFTTPLTPSQYYSGSK 16 0 P49454 P49454 CENPF Centromere protein F 1 0 IFT(0.038)T(0.57)PLT(0.377)PS(0.012)QY(0.003)YSGSK 96.334 0.011191 27346000 1939.3 1459.8 1912.8 1728.9 1864.7 3212.4 3104.9 394.96 1963.3 1540.7 TRUE FALSE FALSE 1785.802359 1585.978607 1983.690051 1721.74627 1842.46467 2546.112029 3192.015138 515.3814858 1747.930902 1594.23921 1.120159602 0.994818467 1.244286327 1.079979879 1.155701515 1.597070259 2.002218436 0.323277387 1.096404411 1 10.6386524 -5.470650538 7.824478969 1.071771888 1.377968846 0.046960949 0.399242836 0.49796477 67.54318877 0.051582864 0.115024698 3.38E-06 5.470650538 0.306196957 IFTTPLT(ph)PSQYYSGSK ddPTM_HeLa_Curcumin_4h_R1 1 IFTTPLTPSQYYSGSK 16 0 P49454 P49454 CENPF Centromere protein F 1 0 IFTTPLT(0.715)PS(0.285)QYYSGSK 168.41 0.00045249 23683000 1809.9 1554.3 1229.9 1050.1 1364 2447.2 2112.8 441.47 1488.9 1210.9 TRUE FALSE FALSE 1666.644505 1688.646766 1275.481176 1045.754964 1347.735191 1939.623134 2172.079482 576.0721707 1325.571395 1252.978685 1.330145936 1.3477059 1.017959197 0.834615127 1.075624994 1.548009681 1.733532667 0.459762147 1.057936109 1 10.29114616 -9.592654407 1.4126956 1.000969341 1.206416884 0.015684491 0.343597344 1.202597063 4.337780232 0.230153836 0.05450327 2.55E-10 9.592654407 0.205447543 IFTTPLT(ph)PSQYYSGSKYEDLKEK ddPTM_HeLa_Curcumin_4h_R1 1 IFTTPLTPSQYYSGSKYEDLKEK 23 2 P49454 P49454 CENPF Centromere protein F 1 0 IFT(0.001)T(0.002)PLT(0.958)PS(0.032)QY(0.006)Y(0.001)SGSKYEDLKEK 70.837 0.00069986 11151000 855.23 577.44 753.19 756.6 710.77 1170.7 1012.7 296.05 1106.1 864.61 TRUE FALSE FALSE 787.5376431 627.3513406 781.103884 753.4693897 702.294532 927.8836235 1041.113636 386.3142822 984.7635973 894.6551331 0.880269518 0.701221417 0.87307819 0.842189758 0.784989105 1.037141116 1.163703865 0.431802454 1.100718658 1 9.805187857 -8.635863869 0.960544659 0.988316322 0.853927761 0.147582567 0.187316382 0.95929014 1.788162634 0.069161231 0.035139452 2.31E-09 8.635863869 -0.134388561 IFVGGIKEDTEEYNLR ddPTM_HeLa_Curcumin_4h_R1 2 IFVGGIKEDTEEYNLR 16 1 P51991;P51991-2 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 0 ; ; 101.61 0.0021481 49602000 2183.4 1703.31 1654.16 2286.8 1505.52 2682.8 2021.5 2761.7 1857.31 2084.35 FALSE FALSE TRUE 2010.581586 1850.536527 1715.464625 2277.337828 1487.567657 2126.357039 2078.217849 3603.729617 1653.56774 2156.781007 0.932214063 0.858008542 0.795381923 1.055896644 0.689716597 0.985893807 0.963573883 1.670883416 0.766683189 1 11.07466398 -4.259792963 5.120923681 0.935670289 1.705357658 0.795366939 0.116577795 0.049759021 4.240675978 0.014053739 0.134646758 5.50E-05 4.259792963 0.769687368 IFVGGLNPEATEEK ddPTM_HeLa_Curcumin_4h_R1 2 IFVGGLNPEATEEK 14 0 Q99729-3;D6R9P3;D6RD18;D6RBZ0;Q99729-2 Q99729-3 HNRNPAB Heterogeneous nuclear ribonucleoprotein A/B 0 0 ; ; 210.44 2.41E-19 3152300 3754.4 2649.2 3203.6 3092.1 3349 4801.7 3292 3141.2 2999.1 2620.28 FALSE FALSE TRUE 3457.235278 2878.185043 3322.328234 3079.305709 3309.065362 3805.773294 3384.36466 4098.93742 2670.106233 2711.334535 1.275104652 1.061538149 1.225347957 1.135715888 1.220456318 1.403653162 1.24822836 1.51177856 0.984794093 1 11.40478741 -1 0.029694709 1.55E-12 3.033649532 0.637290481 0.096526459 713.1919287 1.640991816 54.07254318 128.7217011 0.1 1 3.033649532 IFVGGLS(ph)PDTPEEK ddPTM_HeLa_Curcumin_4h_R1 2 IFVGGLSPDTPEEK 14 0 Q14103-3;D6RAF8;Q14103;H0YA96;H0Y8G5;D6RF44;Q14103-4;Q14103-2 Q14103-3;Q14103-4 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 0 IFVGGLS(0.822)PDT(0.178)PEEK;IFVGGLS(0.57)PDT(0.43)PEEK ; 159.66 0.00030777 72659000 12638 9891 10477.1 11313.6 11663.9 15337.8 12641.4 11205.6 13137.7 10800.6 TRUE FALSE FALSE 11637.68896 10745.93397 10865.39054 11266.78732 11524.81561 12156.56739 12996.08366 14622.13586 11696.52718 11175.92005 1.041318202 0.961525666 0.972214413 1.00813063 1.031218509 1.087746453 1.162864767 1.308360815 1.046582933 1 13.44810598 -4.332556025 1.074849563 1.010419105 1.43293489 0.931661319 0.025884952 0.301887132 0.297806964 0.004324283 0.140492192 4.65E-05 4.332556025 0.422515785 IFVGGLSPDTPEEK ddPTM_HeLa_Curcumin_4h_R1 2 IFVGGLSPDTPEEK 14 0 Q14103-3;D6RAF8;Q14103;H0YA96;H0Y8G5;D6RF44;Q14103-4;Q14103-2 Q14103-3;Q14103-4 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 0 0 ; ; 293.88 1.57E-112 6491100 4637.3 3490.41 3714.8 4003 3803.7 5068.9 3598 3659.2 3928.2 3500.6 FALSE FALSE TRUE 4270.252812 3792.105487 3852.473756 3986.436647 3758.343362 4017.553002 3698.950196 4774.873235 3497.286288 3622.245589 1.178896545 1.046893534 1.063559513 1.100542895 1.037572762 1.109133244 1.021175982 1.318208033 0.965502256 1 11.82266865 -9.601617813 1.404512099 1.000087434 1.111222207 0.262735951 0.083141374 0.534620351 1.894971973 0.055548849 0.012878709 2.50E-10 9.601617813 0.111134774 IFYPEIEEVQALDDTER ddPTM_HeLa_Curcumin_4h_R1 2 IFYPEIEEVQALDDTER 17 0 P33316;A0A0C4DGL3;H0YKC5;H0YNW5;P33316-2 P33316;H0YNW5;P33316-2 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 0 0 ; ; 206.45 7.66E-10 277162300 2340.93 2029.43 2296.41 1965.49 2440.8 3069.91 2256.51 2267.56 2321.24 2071.18 FALSE FALSE TRUE 2155.64292 2204.844886 2381.516975 1957.357323 2411.695054 2433.176061 2319.821598 2958.928605 2066.605779 2143.153351 1.00582766 1.028785404 1.111220984 0.913307171 1.125302141 1.135325225 1.082433787 1.380642502 0.964282737 1 11.06551937 -1 0.605956151 1.008513979 23.59074821 0.728672066 0.064199037 55.75461505 0.38959189 0.010067122 1674.821494 0.1 1 22.58223423 IFYPETTDIYDR ddPTM_HeLa_Curcumin_4h_R1 1 IFYPETTDIYDR 12 0 P46940;A0A0J9YXZ5 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 0 155.53 0.0028834 5121000 1080.8 1070.8 905.8 1320.1 1477.9 1269 1127 1048.4 1032 1171.4 FALSE FALSE TRUE 995.2535395 1163.355181 939.3697448 1314.637776 1460.277008 1005.795095 1158.620587 1368.052334 918.7921819 1212.106063 0.821094432 0.95978002 0.774989725 1.084589721 1.204743588 0.829791325 0.955873931 1.128657282 0.758013024 1 10.24330023 -6.234462524 24.96444138 0.907813373 1.0334098 0.318216452 0.121375614 915.6126034 847310.2359 0.018150516 0.030093846 5.83E-07 6.234462524 0.125596427 IFYPETTDIYDRK ddPTM_HeLa_Curcumin_4h_R1 2 IFYPETTDIYDRK 13 1 P46940;A0A0J9YXZ5 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 0 ; ; 138.63 0.0015752 74762000 4066 3280.8 3496 3262.1 2925.1 3857.5 2992.4 2387.5 3771 3617.4 FALSE FALSE TRUE 3744.17181 3564.377733 3625.564835 3248.602295 2890.220093 3057.411017 3076.35869 3115.437759 3357.330735 3743.104381 1.000285172 0.95225176 0.968598379 0.867889849 0.772145203 0.816811584 0.821873605 0.832313888 0.896937513 1 11.87001956 -6.229838819 2.035867085 0.996518402 0.811093269 0.768649605 0.037867997 0.051949419 0.420121509 0.003400545 0.006009341 5.89E-07 6.229838819 -0.185425133 IGAEVYHNLK ddPTM_HeLa_Curcumin_4h_R1 3 IGAEVYHNLK 10 0 P06733;A0A2R8Y6G6;K7EM90;P06733-2 P06733 ENO1 Alpha-enolase;Enolase 0 0 ;; ;; 128.86 0.00045748 69291000 19409.2 12594.5 16532.7 14296.5 17038.6 24310.1 20069.5 22609 15963 16370 FALSE FALSE TRUE 17872.94134 13683.11246 17145.41641 14237.34487 16835.42582 19267.91123 20632.59616 29502.38002 14211.89884 16938.85628 1.055144518 0.807794354 1.012194455 0.840513942 0.993893894 1.137497769 1.218063121 1.741698467 0.839011714 1 14.04804885 -3.968530981 1.216897447 0.994268205 2.555888292 0.857727982 0.097369688 0.687009468 0.529853423 0.013155334 1.5972302 0.000107515 3.968530981 1.561620087 IGDEDVGR ddPTM_HeLa_Curcumin_4h_R1 1 IGDEDVGR 8 0 P23284 P23284 PPIB Peptidyl-prolyl cis-trans isomerase B 0 0 110.81 0.0060534 8790800 9719.6 5647.1 8621.5 8011.8 8778.4 10465 8998.3 9253.4 7474.4 7007.3 FALSE FALSE TRUE 8950.283404 6135.210161 8941.020374 7978.649294 8673.723313 8294.441035 9250.76808 12074.71906 6654.47702 7250.803153 1.234385104 0.846142149 1.233107586 1.100381451 1.19624311 1.143934108 1.275826675 1.66529401 0.91775723 1 12.82392509 IGDEYAEDS(ph)S(ph)DEEDIR ddPTM_HeLa_Curcumin_4h_R1 2 IGDEYAEDSSDEEDIR 16 0 Q14137;Q14137-2;A0A075B729 Q14137 BOP1 Ribosome biogenesis protein BOP1 2 0 IGDEY(0.001)AEDS(0.999)S(1)DEEDIR;IGDEY(0.002)AEDS(0.998)S(1)DEEDIR ; 95.195 0.0099201 73321000 3509.59 3112.6 3511.5 3314 4516.3 4360.5 3473.1 2794.76 3323.88 3345.2 TRUE FALSE FALSE 3231.802248 3381.639275 3641.639279 3300.287546 4462.446072 3456.083147 3570.545839 3646.869459 2959.25868 3461.445451 0.933656848 0.976944263 1.052057394 0.953442021 1.289185728 0.998450848 1.031518737 1.053568375 0.854919923 1 11.7571589 -6.40385962 1.707842009 0.969014932 1.076054904 0.284161352 0.091237208 0.378321551 2.172805104 0.01340236 0.022661197 3.95E-07 6.40385962 0.107039973 IGDFGLATVK ddPTM_HeLa_Curcumin_4h_R1 1 IGDFGLATVK 10 0 H7C155;P04049;P04049-2;H7C4S5;H7C560;A0A2U3TZI2;A0A2R8Y8E0;P15056;A0A2R8Y492;Q96II5;P10398 H7C155;H7C560;Q96II5 RAF1;BRAF;ARAF RAF proto-oncogene serine/threonine-protein kinase;Serine/threonine-protein kinase B-raf;Serine/threonine-protein kinase A-Raf 0 0 95.815 0.015132 2228800 3855.5 3466.2 2807 3667.8 3153 40.438 1113.5 782.69 3364.2 2925.9 FALSE FALSE TRUE 3550.333107 3765.802883 2911.029889 3652.623615 3115.402534 32.05070297 1144.741813 1021.328578 2995.155677 3027.574807 1.172665692 1.243834793 0.96150552 1.206451978 1.029009267 0.010586263 0.378105212 0.337342144 0.989292046 1 11.56394689 -5.305725631 8.06961538 1.093780713 0.256157178 0.900991186 0.128194849 0.061677985 10.45487845 0.01788392 0.040318503 4.95E-06 5.305725631 -0.837623535 IGDS(ph)SQGDNNLQK ddPTM_HeLa_Curcumin_4h_R1 1 IGDSSQGDNNLQK 13 0 A0A0D9SG77;A0A1B0GVL3;Q05086-2;Q05086-3;Q05086 A0A0D9SG77 UBE3A Ubiquitin-protein ligase E3A 1 0 IGDS(0.675)S(0.325)QGDNNLQK 102.33 0.0070515 0 1368 1421.2 1646.6 1448 1672.8 1765.1 1292.6 1512.2 1677.4 1569.4 TRUE FALSE FALSE 1259.721356 1544.042195 1707.624444 1442.00856 1652.852953 1398.998363 1328.866877 1973.262819 1493.393417 1623.936533 0.775720806 0.950802056 1.051533979 0.887971008 1.017806373 0.861485861 0.818299761 1.215110799 0.919613166 1 10.66527953 -7.02555106 24.80825529 0.892467804 0.96435511 0.074320678 0.117053104 1530.748096 1486244.646 0.021082661 0.025878892 9.43E-08 7.02555106 0.071887307 IGEEQS(ph)AEDAEDGPPELLFIHGGHTAK ddPTM_HeLa_Curcumin_4h_R1 3 IGEEQSAEDAEDGPPELLFIHGGHTAK 27 0 E9PC52;Q16576;Q16576-2;Q5JNZ6 E9PC52 RBBP7 Histone-binding protein RBBP7 1 0 IGEEQS(1)AEDAEDGPPELLFIHGGHTAK;IGEEQS(1)AEDAEDGPPELLFIHGGHTAK;IGEEQS(1)AEDAEDGPPELLFIHGGHTAK ;; 103.31 4.95E-08 85865000 10924 7870.2 10057 8953.9 9859.1 13521.4 8946.1 8656.6 10694.9 9559.4 TRUE FALSE FALSE 10059.35387 8550.465019 10429.72127 8916.851134 9741.536672 10716.90922 9197.103489 11295.95749 9521.696227 9891.588438 1.016960414 0.86441779 1.054403075 0.90145796 0.984830367 1.083436628 0.929790351 1.14197609 0.962605378 1 13.2719865 -4.244818155 24.37710051 0.994147364 1.141976254 0.337991429 0.06542372 2078.155108 3047806.852 0.008148946 0.295709957 5.69E-05 4.244818155 0.14782889 IGEEQS(ph)PEDAEDGPPELLFIHGGHTAK ddPTM_HeLa_Curcumin_4h_R1 2 IGEEQSPEDAEDGPPELLFIHGGHTAK 27 0 Q09028-3;Q09028;Q09028-2;Q09028-4;H0YF10;H0YEU5;H0YCT5;H0YDK2 Q09028-3 RBBP4 Histone-binding protein RBBP4 1 0 IGEEQS(1)PEDAEDGPPELLFIHGGHTAK;IGEEQS(1)PEDAEDGPPELLFIHGGHTAK ; 95.444 1.44E-06 10052000 2964.1 2101.2 2692.08 2386.19 2414.66 3590.5 2689.25 2889.28 2999.2 2571.56 TRUE FALSE FALSE 2729.488357 2282.818365 2791.850853 2376.316578 2385.866757 2845.789827 2764.703117 3770.208171 2670.195264 2660.921519 1.02576808 0.857905184 1.049204508 0.893042715 0.896631765 1.069475295 1.039002127 1.416880635 1.003485163 1 11.37771024 -4.036821461 1.818105339 0.98950436 1.787316344 0.78577508 0.068530748 0.620257987 1.246117752 0.009732741 1.022124139 9.19E-05 4.036821461 0.797811984 IGEEQSAEDAEDGPPELLFIHGGHTAK ddPTM_HeLa_Curcumin_4h_R1 1 IGEEQSAEDAEDGPPELLFIHGGHTAK 27 0 E9PC52;Q16576;Q16576-2;Q5JNZ6 E9PC52 RBBP7 Histone-binding protein RBBP7 0 0 88.186 5.41E-06 6347600 1329.1 1179.9 1162.5 1080.1 1087.8 1752.1 1043.3 1205.2 1294.2 1153.3 FALSE FALSE TRUE 1223.900333 1281.885298 1205.583273 1075.630832 1074.828695 1388.69471 1072.57219 1572.659932 1152.229498 1193.377089 1.025577199 1.074166171 1.01022827 0.90133357 0.900661413 1.163667983 0.898770556 1.317823131 0.965520043 1 10.22083427 -4.248874505 24.76426923 1.005948849 1.317823354 0.589033495 0.080696585 906.1547369 1785916.595 0.010112555 0.2355945 5.64E-05 4.248874505 0.311874505 IGEEQSPEDAEDGPPELLFIHGGHTAK ddPTM_HeLa_Curcumin_4h_R1 1 IGEEQSPEDAEDGPPELLFIHGGHTAK 27 0 Q09028-3;Q09028;Q09028-2;Q09028-4;H0YF10;H0YEU5;H0YCT5;H0YDK2 Q09028-3 RBBP4 Histone-binding protein RBBP4 0 0 91.503 1.77E-06 4325400 1019.3 861.46 977.23 793.39 985.5 1641.4 1106 967.72 1032.5 1100.5 FALSE FALSE TRUE 938.6213294 935.9207638 1013.447003 790.1071624 973.7485562 1300.955138 1137.031383 1262.773373 919.2373332 1138.742293 0.824261411 0.821889878 0.889970461 0.693841941 0.8551088 1.142449126 0.998497544 1.108919359 0.807239126 1 10.15322557 -5.268467694 24.85757376 0.885093092 1.074809565 0.589443937 0.087190567 365.9215513 1294184.637 0.014792077 0.033738473 5.39E-06 5.268467694 0.189716472 IGEGT(ph)Y(ph)GVVYK ddPTM_HeLa_Curcumin_4h_R1 1 IGEGTYGVVYK 11 0 A0A087WZZ9;P06493;E5RIU6;A0A024QZP7;P06493-2;G3V317;K7ELV5;E7ESI2;P24941-2;G3V5T9;P24941;Q00526 A0A087WZZ9;G3V5T9 CDK1;CDC2;CDK2;CDK3 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 2 0 IGEGT(1)Y(1)GVVYK 134.99 0.010805 32359000 2818.7 2817.7 2612.1 3006.3 2587 4342.9 4304.4 4415.3 3233 4570.8 TRUE FALSE FALSE 2595.596921 3061.249433 2708.906724 2993.860727 2556.151715 3442.133585 4425.169879 5761.504644 2878.347989 4729.63496 0.548794345 0.647248563 0.572751755 0.63300038 0.540454335 0.727779969 0.935626093 1.218171105 0.608577197 1 12.20751312 -4.433470873 2.389075248 0.725686427 1.249015606 0.592825927 0.139251804 0.326777647 2.848293464 0.028022072 0.298754805 3.69E-05 4.433470873 0.523329179 IGEGT(ph)YGVVYK ddPTM_HeLa_Curcumin_4h_R1 1 IGEGTYGVVYK 11 0 A0A087WZZ9;P06493;E5RIU6;A0A024QZP7;P06493-2;G3V317;K7ELV5;E7ESI2;P24941-2;G3V5T9;P24941;Q00526 A0A087WZZ9;G3V5T9 CDK1;CDC2;CDK2;CDK3 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 1 0 IGEGT(1)YGVVYK 128.85 0.0087476 8190900 927.27 814.02 908.44 863.53 821.25 1038.2 972.59 1120.7 909.54 1176.1 TRUE FALSE FALSE 853.875601 884.3802616 942.1075855 859.9569417 811.4571301 822.8656171 999.8782578 1462.396271 809.7657376 1216.969387 0.701640986 0.726707073 0.774142386 0.706638105 0.666785162 0.676159668 0.821613319 1.201670548 0.665395322 1 10.24907716 -9.375815444 1.081939033 1.000929124 0.768120988 0 0.180074993 0.583322262 1.213891254 0.103273482 0.026201544 4.21E-10 9.375815444 -0.232808136 IGEGTY(ph)GTVFK ddPTM_HeLa_Curcumin_4h_R1 1 IGEGTYGTVFK 11 0 Q00535-2;Q00535 Q00535-2 CDK5 Cyclin-dependent-like kinase 5 1 0 IGEGT(0.205)Y(0.72)GT(0.075)VFK 142 0.0076382 6274100 1709.7 1543.7 1342.1 1490.4 1314.2 1769 1469.5 1156 1696.1 1650.1 TRUE FALSE FALSE 1574.375441 1677.130549 1391.839407 1484.23312 1298.529023 1402.089459 1510.730215 1508.459078 1510.042073 1707.440852 0.922067338 0.98224811 0.815161125 0.86927352 0.760511863 0.821164292 0.884792122 0.883461981 0.884389097 1 10.73761989 -6.762635702 24.99999605 0.963598915 0.838128925 0.553973064 0.046598458 14.916107 311709.7465 0.007275622 0.00986569 1.73E-07 6.762635702 -0.12546999 IGEGTY(ph)GVVYK ddPTM_HeLa_Curcumin_4h_R1 3 IGEGTYGVVYK 11 0 A0A087WZZ9;P06493;E5RIU6;A0A024QZP7;P06493-2;G3V317;K7ELV5;E7ESI2;P24941-2;G3V5T9;P24941;Q00526 A0A087WZZ9;G3V5T9 CDK1;CDC2;CDK2;CDK3 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 1 0 IGEGT(0.005)Y(0.995)GVVYK;IGEGT(0.106)Y(0.894)GVVYK;IGEGT(0.009)Y(0.988)GVVY(0.003)K ;; 163.16 0.0018164 3125149000 11179.9 8742.23 9828.5 9677.06 9665.89 10429.2 8982.6 7387.6 10051.9 9804.96 TRUE FALSE FALSE 10294.99912 9497.869407 10192.75286 9637.01889 9550.630575 8266.066359 9234.627581 9640.045232 8949.231719 10145.68163 1.014717344 0.93614897 1.004639533 0.949864114 0.941349327 0.814737408 0.910202776 0.950162402 0.882072989 1 13.30857817 -5.923935391 1.581191591 1.001551479 0.893858867 0.114351607 0.054478232 0.193824272 0.972332156 0.006128854 0.01333718 1.19E-06 5.923935391 -0.107692612 IGEGTYGVVYK ddPTM_HeLa_Curcumin_4h_R1 3 IGEGTYGVVYK 11 0 A0A087WZZ9;P06493;E5RIU6;A0A024QZP7;P06493-2;G3V317;K7ELV5;E7ESI2;P24941-2;G3V5T9;P24941;Q00526 A0A087WZZ9;G3V5T9 CDK1;CDC2;CDK2;CDK3 Cyclin-dependent kinase 1;Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 0 0 ;; ;; 186.78 0.00058745 90395100 8876.5 7315.4 7396.7 7276.2 7735.8 9493.3 7459.8 5923.4 8476.7 8178.8 FALSE FALSE TRUE 8173.915659 7947.710579 7670.828209 7246.093012 7643.555637 7524.282568 7669.101911 7729.417392 7546.827218 8463.012691 0.965839939 0.939111268 0.906394506 0.856207272 0.903171946 0.889078493 0.906190525 0.913317476 0.891742396 1 13.04695561 -7.167708377 1.233621005 0.988109872 0.893318201 0.227678094 0.034387019 0.111574226 0.327477761 0.003549333 0.004394526 6.80E-08 7.167708377 -0.09479167 IGEHMEEHGIK ddPTM_HeLa_Curcumin_4h_R1 5 IGEHMEEHGIK 11 0 E2QRB9;E9PIR7;F8W809;A0A087WSW9;A0A182DWI3;A0A087WSY9;Q16881-7;Q16881-5;Q16881-2;Q16881-4;Q16881-3;Q16881-6;Q16881 E2QRB9 TXNRD1 "Thioredoxin reductase 1, cytoplasmic" 0 0 ;;;; ;;;; 117.31 0.00044093 43753500 24273.7 19628.5 21707.3 21187.7 22501.2 25974.5 20155 19838.3 23483.7 21158.1 FALSE FALSE TRUE 22352.41103 21325.10008 22511.79163 21100.03091 22232.88789 20587.09591 20720.49506 25886.90635 20907.59686 21893.3424 1.020968412 0.974044972 1.028248279 0.963764716 1.015509075 0.940335904 0.946429041 1.182409971 0.954975101 1 14.4182046 -4.251247164 24.7454753 0.998405505 1.182410088 0.746298456 0.033834901 469.878605 1140783.227 0.004407187 0.08008908 5.61E-05 4.251247164 0.184004583 IGEHTPSALAIMENANVLAR ddPTM_HeLa_Curcumin_4h_R1 3 IGEHTPSALAIMENANVLAR 20 0 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BR04;H3BU78 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 ;; ;; 159.44 8.64E-06 49377500 5107.1 3751.5 4917.84 4900.2 3672.87 5703.8 4858.8 4304.08 3659.98 3184.48 FALSE FALSE TRUE 4702.867646 4075.762944 5100.099477 4879.924271 3629.073424 4520.767585 4995.124851 5616.374178 3258.489351 3295.140443 1.427213112 1.236901132 1.547763916 1.480945761 1.101341047 1.371949895 1.515906511 1.704441518 0.988877229 1 11.68612424 -11.8631625 0.231090714 1.57E-12 1.486688245 0.574338325 0.151867563 13.93679915 0.351967957 6.667323489 0.125086349 1.37E-12 11.8631625 1.486688245 IGEK(ac)SLFTK ddPTM_HeLa_Curcumin_4h_R1 2 IGEKSLFTK 9 1 A0A3B3IU56;F5GY90;A0A1W2PNU5;F5H226;A0A3B3IU34;F5H0P4;F5H345;A0A3B3IRR1;A0A3F2YNY7;P08397-4;P08397-3;P08397-2;P08397 A0A3B3IU56 HMBS Porphobilinogen deaminase 0 1 ; IGEK(1)SLFTK;IGEK(1)SLFTK 97.813 0.01189 4283000 2255.86 2125.23 2449.4 1922.08 2034.3 2972.2 1878.87 1481.62 2177.19 1608.64 FALSE TRUE FALSE 2077.306301 2308.925411 2540.176919 1914.126942 2010.042301 2355.732216 1931.586035 1933.359117 1938.357704 1664.54012 1.247976108 1.387125118 1.526053285 1.14994341 1.207566148 1.41524508 1.160432249 1.161497457 1.164500441 1 10.70090793 -8.766013505 0.861186897 1.013590522 1.284600512 0.249446628 0.128254555 0.406222245 0.594060187 0.060942792 0.02551993 1.71E-09 8.766013505 0.27100999 IGELGAPEVWGLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 IGELGAPEVWGLSPK 15 0 A0A494C050;Q8N5F7 A0A494C050 NKAP NF-kappa-B-activating protein 1 0 IGELGAPEVWGLS(1)PK;IGELGAPEVWGLS(1)PK ; 125.61 0.00090137 897650000 14612.9 13210.8 14409 13562 14568 15658.2 14943.9 10501.2 13777.7 11555.9 TRUE FALSE FALSE 13456.27355 14352.68269 14943.01022 13505.88404 14394.28611 12410.51282 15363.18561 13702.96754 12266.32078 11957.46666 1.125344851 1.200311327 1.249680274 1.129493765 1.203790612 1.037888138 1.284819439 1.145975809 1.025829394 1 13.54562415 -8.410987012 0.714197671 1.007686209 1.178821172 0.487278561 0.065677737 0.362275763 0.38991415 0.029451245 0.014809522 3.88E-09 8.410987012 0.171134962 IGEVSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 IGEVSSPK 8 0 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 0 IGEVS(0.095)S(0.905)PK 96.665 0.017005 52694000 10637 6809.4 9459.7 11460 11613 11595 10264 2247.7 10395 8837.8 TRUE FALSE FALSE 9795.070226 7397.974194 9810.284804 11412.58156 11474.52256 9190.066297 10551.98022 2933.013383 9254.694507 9144.912892 1.071094973 0.808971532 1.072758693 1.247970505 1.254743779 1.004937544 1.153863393 0.320726224 1.012004665 1 13.15875371 -4.256714977 24.91065716 1.054980468 0.320725911 0.76390335 0.124658977 176.2215821 929140.846 0.017542092 0.19049461 5.54E-05 4.256714977 -0.734254557 IGFAEK(ac)VAAK ddPTM_HeLa_Curcumin_4h_R1 1 IGFAEKVAAK 10 1 P07954-2;P07954 P07954-2 FH "Fumarate hydratase, mitochondrial" 0 1 IGFAEK(1)VAAK 117.53 0.0032583 658750 894.23 792.93 852.38 933.21 977.33 982.01 714.47 722 1238.5 1059.7 FALSE TRUE FALSE 823.4507519 861.467336 883.9699526 929.3486243 965.6759781 778.3300565 734.5161053 942.1344763 1102.639649 1096.524496 0.750964301 0.785634374 0.806156138 0.847540231 0.880669772 0.709815475 0.669858364 0.859200574 1.00557685 1 10.09872233 -9.314287004 0.844300295 1.012104779 0.784982494 0.646233761 0.063031336 0.382143266 0.44630773 0.058228996 0.012615934 4.85E-10 9.314287004 -0.227122285 IGFPS(ph)TSPAK ddPTM_HeLa_Curcumin_4h_R1 1 IGFPSTSPAK 10 0 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 0 IGFPS(0.627)T(0.23)S(0.143)PAK 105.17 0.0096883 60105000 5251.3 3039.5 4227.4 3813.1 4161 5189.2 4768.1 3078 4200.2 4289.6 TRUE FALSE FALSE 4835.654064 3302.220836 4384.071163 3797.322403 4111.382793 4112.901426 4901.880053 4016.468031 3739.448568 4438.663281 1.089439265 0.743967413 0.987700775 0.855510356 0.92626598 0.926608117 1.104359521 0.904882343 0.842471783 1 12.11590955 IGFPS(ph)TTPAK ddPTM_HeLa_Curcumin_4h_R1 1 IGFPSTTPAK 10 0 F5H1T5;F5H6A0;J3KP58;P30622-2;P30622-1;P30622;F5H0N7 F5H1T5 CLIP1 CAP-Gly domain-containing linker protein 1 1 0 IGFPS(0.462)T(0.327)T(0.211)PAK 91.549 0.018185 71364000 4725.6 3879.7 3809.7 4042.3 3930.3 6902.1 8030.7 3848.6 4946.9 3445.4 TRUE FALSE FALSE 4351.563774 4215.04398 3950.890833 4025.574034 3883.433739 5470.526657 8256.019828 5022.020423 4404.237447 3565.127394 1.220591382 1.182298279 1.108204672 1.129152928 1.089283302 1.534454748 2.315771336 1.408651044 1.235366078 1 11.79973791 -5.06807859 3.993765704 1.115410821 1.878321902 0.645492809 0.216179656 0.08313846 2.56621014 0.027553983 0.078144504 8.55E-06 5.06807859 0.762911081 IGGDAATTVNNS(ph)TPDFGFGGQKR ddPTM_HeLa_Curcumin_4h_R1 1 IGGDAATTVNNSTPDFGFGGQKR 23 1 A0A087WTP3;Q92945;M0R0I5 A0A087WTP3 KHSRP Far upstream element-binding protein 2 1 0 IGGDAATTVNNS(0.5)T(0.5)PDFGFGGQKR 89.803 9.77E-05 14169000 892.52 596.11 744.97 591.44 406.65 829.03 1036.6 883.16 799.92 855.2 TRUE FALSE FALSE 821.8761002 647.6350922 772.5792435 588.992778 401.8009643 657.0798329 1065.684206 1152.431418 712.1707773 884.9181363 0.928759471 0.731858763 0.873051655 0.665590131 0.45405439 0.742531773 1.204274342 1.302302858 0.804787187 1 9.789400188 -4.656816484 5.696836884 0.872585932 1.275199574 0.510311644 0.167561232 0.160814007 7.401851418 0.028140718 0.10929967 2.20E-05 4.656816484 0.402613642 IGGIGTVPVGR ddPTM_HeLa_Curcumin_4h_R1 2 IGGIGTVPVGR 11 0 A0A2U3TZH3;Q05639;Q5VTE0;P68104;A0A087WVQ9 A0A2U3TZH3;Q5VTE0 EEF1A2;EEF1A1P5;EEF1A1 Elongation factor 1-alpha 2;Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1 0 0 ; ; 137.14 0.00030145 245430000 2559.2 2188.99 2239.33 2280.33 2604.7 2742 2067.84 2399.6 2623.5 2391.4 FALSE FALSE TRUE 2356.63662 2378.196542 2322.32154 2270.894599 2573.640654 2173.278291 2125.858025 3131.226994 2335.708614 2474.500972 0.952368436 0.961081272 0.938500961 0.917718208 1.040064515 0.878269322 0.859105755 1.265397359 0.94391097 1 11.27292189 -4.249334863 24.99768592 0.961041437 1.265397544 0.765276421 0.052686035 745.3396576 1539214.243 0.007443101 0.169349024 5.63E-05 4.249334863 0.304356106 IGGNEGIDVPIPR ddPTM_HeLa_Curcumin_4h_R1 2 IGGNEGIDVPIPR 13 0 Q96AE4;E9PEB5;Q96AE4-2 Q96AE4 FUBP1 Far upstream element-binding protein 1 0 0 ; ; 165.63 1.05E-05 4415200 3791.7 2749.5 2996.5 3100.6 3055.5 3981.5 3075.5 3180.9 3405.9 3373.5 FALSE FALSE TRUE 3491.582944 2987.154528 3107.552926 3087.770539 3019.065158 3155.692019 3161.790253 4150.741767 3032.281291 3490.728874 1.000244668 0.855739485 0.89023039 0.884563268 0.864881023 0.904020946 0.905767926 1.189075954 0.86866709 1 11.76931259 -7.306905989 21.58644775 1.000115629 0.920473111 0 0.099698654 127.2030441 60392.36367 0.014867602 0.017001883 4.93E-08 7.306905989 -0.079642518 IGHPAPNFK ddPTM_HeLa_Curcumin_4h_R1 3 IGHPAPNFK 9 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 0 ;; ;; 98.629 0.011122 135736000 37174 28601.7 31288.7 32133.1 32692.9 36872 29373.9 27605.4 34082.3 31308.5 FALSE FALSE TRUE 34231.63867 31073.9035 32448.28675 32000.14175 32303.05852 29224.33157 30198.05258 36022.15938 30343.55696 32396.46804 1.056647244 0.959175656 1.001599517 0.987766373 0.997116676 0.902083879 0.932140273 1.111916254 0.936631639 1 14.98354891 -7.254968693 24.87593478 1.026750087 0.980619331 0 0.060589523 707.5453538 2720086.869 0.008950605 0.010811609 5.56E-08 7.254968693 -0.046130756 IGIEIIK ddPTM_HeLa_Curcumin_4h_R1 1 IGIEIIK 7 0 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 119.89 0.0095456 4760100 3261.8 3227.6 3914.9 3502.3 4033.1 5370.5 3986.1 4195.7 3226.2 2605.9 FALSE FALSE TRUE 3003.625088 3506.579362 4059.989638 3487.808411 3985.007917 4256.597762 4097.939238 5474.949615 2872.293932 2696.454831 1.113916337 1.300440609 1.505676858 1.293479264 1.477869338 1.578590419 1.519750745 2.030425117 1.065211217 1 11.39684815 -1 0.181854288 0.919088019 5.146114262 0.845989662 0.113385971 13.38533899 0.146161258 0.135086628 15.77818854 0.1 1 4.227026243 up IGIEIIK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 IGIEIIKR 8 1 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 1 ; IGIEIIK(1)R;IGIEIIK(1)R 93.162 0.0066291 5411400 1867.65 3838.3 2201.3 1950.66 2780.9 5546.6 5055.9 4481.8 3398.7 1711.07 FALSE TRUE FALSE 1719.823532 4170.065549 2282.882114 1942.588686 2747.739584 4396.172637 5197.754947 5848.280188 3025.871113 1770.529555 0.971361097 2.35526458 1.289378146 1.097179474 1.551930933 2.48297049 2.9357064 3.30312486 1.709020391 1 10.78996521 -3.00012698 0.365436532 0.976154823 9.203971712 0.656279522 0.469998671 4.549545862 0.20856176 0.122114745 20.06379067 0.000999708 3.00012698 8.227816889 IGIIGGTGLDDPEILEGR ddPTM_HeLa_Curcumin_4h_R1 2 IGIIGGTGLDDPEILEGR 18 0 F8WES2;F2Z2F3;J3QSB7;B4DUC8;Q13126-7;Q13126-4;Q13126;Q13126-6;Q13126-5;Q13126-3;Q13126-2 F8WES2 MTAP Purine nucleoside phosphorylase;S-methyl-5-thioadenosine phosphorylase 0 0 ; ; 118.61 0.0033943 5678800 2517.1 2300 2287.4 2751.4 2651.1 3277 2659.3 2525.24 3044.3 2640.2 FALSE FALSE TRUE 2317.868879 2498.801751 2372.173056 2740.015436 2619.487364 2597.313261 2733.912801 3295.174051 2710.347906 2731.946753 0.848431206 0.914659756 0.868308672 1.002953455 0.958835439 0.950718844 1.000719651 1.206163351 0.992093972 1 11.41571365 -1.00000365 0.89445409 0.926654379 136.1633854 0.706932548 0.050693121 408.7027172 0.884035299 0.009686162 112820.0278 0.09999916 1.00000365 135.236731 IGK(ac)TLPSEK ddPTM_HeLa_Curcumin_4h_R1 2 IGKTLPSEK 9 1 Q14966-3;Q14966;Q14966-5;A0A096LNS4 Q14966-3 ZNF638 Zinc finger protein 638 0 1 ; IGK(1)TLPSEK;IGK(1)TLPSEK 105.4 0.0050334 14270900 7580.8 6277.6 6321.4 6552.5 6495.8 5668.5 5953.4 4288.4 7473.9 6245.9 FALSE TRUE FALSE 6980.771681 6820.207772 6555.676645 6525.387491 6418.341828 4492.789203 6120.436381 5595.913419 6654.031869 6462.94456 1.080122476 1.055278706 1.014348272 1.009661684 0.993098698 0.69516134 0.947004314 0.865845802 1.029566602 1 12.6579759 -5.4694749 10.07876258 1.035070435 0.84637197 0.667794879 0.061761825 0.286762223 53.04003473 0.008767095 0.019575356 3.39E-06 5.4694749 -0.188698465 IGLFGGAGVGK ddPTM_HeLa_Curcumin_4h_R1 2 IGLFGGAGVGK 11 0 P06576;H0YH81;F8W079 P06576 ATP5B "ATP synthase subunit beta, mitochondrial;ATP synthase subunit beta" 0 0 ; ; 136.16 0.00038126 10138300 4940 4785.3 5313.6 5421.3 5987.3 8141.8 5966.2 5721.9 5895.7 4587.6 FALSE FALSE TRUE 4548.993787 5198.920009 5510.52669 5398.868097 5915.905358 6453.098903 6133.595515 7466.48097 5248.95646 4747.018759 0.95828435 1.095196854 1.16083946 1.137317624 1.246235934 1.359400338 1.292094223 1.572877915 1.105737459 1 12.21280604 -4.837403903 0.408385359 0.968444905 1.73073693 0.831974868 0.070797424 0.738078468 0.114675852 0.017060041 0.252902768 1.45E-05 4.837403903 0.762292026 IGPLGLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 IGPLGLSPK 9 0 P30050 P30050 RPL12 60S ribosomal protein L12 1 0 IGPLGLS(1)PK 96.756 0.015032 437740000 4219.1 4044.1 3585.8 4185.8 4055.9 5432.7 3043.5 3616 4406.3 3787.9 TRUE FALSE FALSE 3885.153783 4393.653984 3718.692902 4168.480269 4007.536041 4305.896781 3128.892419 4718.501754 3922.939914 3919.529243 0.991229697 1.120964716 0.948760086 1.063515542 1.02245341 1.098574985 0.798282708 1.203843998 1.000870174 1 11.93646467 IGPLGLSPK ddPTM_HeLa_Curcumin_4h_R1 2 IGPLGLSPK 9 0 P30050 P30050 RPL12 60S ribosomal protein L12 0 0 ; ; 113.41 0.0025081 5254200 6467.2 2867.9 4863.7 5467.6 5333.7 6164.5 5435.5 4141.3 4296.3 4469.4 FALSE FALSE TRUE 5955.314296 3115.788497 5043.953001 5444.97652 5270.099111 4885.913212 5588.005501 5403.963306 3825.006639 4624.711317 1.2877159 0.673726052 1.090652509 1.177365709 1.139552017 1.056479611 1.208292825 1.168497434 0.827080087 1 12.1751476 -6.283727418 21.05558563 1.094221529 1.14749373 0.018355302 0.175467425 454.2747962 429153.6439 0.027198224 0.041588869 5.20E-07 6.283727418 0.053272201 SKEFVSSDESS(ph)S(ph)GENK ddPTM_HeLa_Curcumin_4h_R1 1 SKEFVSSDESSSGENK 16 1 Q08945 Q08945 SSRP1 FACT complex subunit SSRP1 2 0 S(0.044)KEFVS(0.162)S(0.296)DES(0.182)S(0.606)S(0.709)GENK 71.316 0.017015 4767900 3233.1 3124.4 2718.6 2945.6 2937 3135 1982.6 1063.9 3483 2864.6 TRUE FALSE FALSE 2977.196723 3394.459214 2819.353708 2933.411888 2901.978193 2484.765661 2038.22642 1388.278212 3100.923614 2964.144637 1.004403323 1.145173273 0.951152542 0.989631832 0.97902719 0.838274094 0.687627181 0.468357109 1.046144502 1 11.53340013 -4.45863321 1.006105292 1.01150424 0.289723784 0.933096871 0.048616836 0.236946246 0.228719053 0.007137518 0.169912237 3.48E-05 4.45863321 -0.721780456 down IGTLHTS(ph)PDLK ddPTM_HeLa_Curcumin_4h_R1 1 IGTLHTSPDLK 11 0 Q9UPZ3-2;Q9UPZ3 Q9UPZ3-2 HPS5 Hermansky-Pudlak syndrome 5 protein 1 0 IGTLHT(0.105)S(0.895)PDLK 211.63 4.18E-08 36657000 4092.9 3444.9 3313 3800.3 3785.7 3461.2 2218.4 1483.1 4192.1 3869.3 TRUE FALSE FALSE 3768.942646 3742.661806 3435.782694 3784.575366 3740.558 2743.308104 2280.642333 1935.290363 3732.237118 4003.757887 0.941351289 0.934787245 0.858139476 0.9452558 0.934261787 0.685183316 0.569625436 0.48336848 0.932183519 1 11.96713902 -5.027086755 1.544566325 0.959840254 0.487888362 0.944963814 0.040400071 0.072818418 0.313195836 0.006848556 0.033276824 9.40E-06 5.027086755 -0.471951892 IGTLQDRPPS(ph)PFREPPGSER ddPTM_HeLa_Curcumin_4h_R1 1 IGTLQDRPPSPFREPPGSER 20 2 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 0 IGTLQDRPPS(0.848)PFREPPGS(0.152)ER 67.552 0.005445 29492000 720.99 423.83 816.01 670.84 745.99 639.99 435.64 339.92 897.85 505.14 TRUE FALSE FALSE 663.9228807 460.4639767 846.2520484 668.0642418 737.0945565 507.2488598 447.8628859 443.5600432 799.3581013 522.6935774 1.270195215 0.880944394 1.619021325 1.278118329 1.410184836 0.970451679 0.856836405 0.848604349 1.529305382 1 9.029821622 -5.032308785 9.151843726 1.177614469 0.867479463 0.330417173 0.226124673 0.361415985 99.89576223 0.029730387 0.077566538 9.28E-06 5.032308785 -0.310135006 IGTSGGIG ddPTM_HeLa_Curcumin_4h_R1 1 IGTSGGIG 8 0 C9JIP2 C9JIP2 UPP1 0 0 93.593 0.019277 6566600 3373.2 4075.9 3115.3 4254.9 3029.6 7873.7 4306.3 1301 4790.5 3241.5 FALSE FALSE TRUE 3106.207661 4428.202634 3230.755758 4237.294351 2993.473999 6240.605865 4427.123188 1697.668911 4264.994135 3354.141884 0.926081176 1.320219236 0.963213803 1.26330206 0.892470892 1.860567049 1.319897411 0.506141055 1.271560442 1 11.711728 -7.279938092 24.05465327 0.965093879 1.179880226 0 0.344924449 946.4604979 1230719.186 0.054163054 0.06200557 5.25E-08 7.279938092 0.214786347 KKPGDASSLPDAGLS(ph)PGSQVDSK ddPTM_HeLa_Curcumin_4h_R1 2 KKPGDASSLPDAGLSPGSQVDSK 23 2 M0R0P8;Q13459-2;Q13459;M0R300 M0R0P8 MYO9B Unconventional myosin-IXb 1 0 KKPGDASSLPDAGLS(0.846)PGS(0.152)QVDS(0.002)K;KKPGDASSLPDAGLS(0.954)PGS(0.046)QVDSK ; 114.73 7.03E-05 11804000 3195.4 2885.8 2956.5 3049.7 2765.6 3917.8 3466.7 9287.8 3635.9 3020.7 TRUE FALSE FALSE 2942.480718 3135.235693 3066.070491 3037.081149 2732.622026 3105.204117 3563.966272 12119.60746 3237.050867 3125.6691 0.941392266 1.003060654 0.980932528 0.971657924 0.874251861 0.993452607 1.140225071 3.877444181 1.035634535 1 11.60994934 -4.25995443 4.561796629 0.970986818 4.067354934 0.997734811 0.041291586 0.006227531 0.334362503 0.00591376 0.061656485 5.50E-05 4.25995443 3.096368116 up VTS(ph)PTTYVLDEDEPR ddPTM_HeLa_Curcumin_4h_R1 3 VTSPTTYVLDEDEPR 15 0 J3KNS1;Q9UPW5;Q9UPW5-2;Q9UPW5-3 J3KNS1 AGTPBP1 Cytosolic carboxypeptidase 1 1 0 VTS(0.991)PT(0.009)TYVLDEDEPR;VT(0.005)S(0.917)PT(0.075)T(0.003)YVLDEDEPR;VT(0.067)S(0.921)PT(0.009)T(0.003)YVLDEDEPR ;; 266.77 1.56E-50 27288600 4384.2 3269.4 3565.26 3426.23 3648.3 4819.5 4217 9407.4 4262.6 3640.68 TRUE FALSE FALSE 4037.185944 3551.992368 3697.391672 3412.053168 3604.796405 3819.881373 4335.317671 12275.67295 3795.003444 3767.193359 1.071669426 0.942874981 0.98147117 0.905728176 0.956891792 1.013986013 1.150808376 3.258572572 1.007382176 1 11.87927437 -4.259913385 4.455464492 1.010239691 3.415190302 0.994987909 0.048117953 0.011760072 0.57707788 0.008339727 0.088776559 5.50E-05 4.259913385 2.404950611 up IGVLDEGK ddPTM_HeLa_Curcumin_4h_R1 2 IGVLDEGK 8 0 P46781;B5MCT8;C9JM19 P46781 RPS9 40S ribosomal protein S9 0 0 ; ; 133.12 0.0013608 13804300 14917.7 14627.4 12581.9 13373.9 13837.4 13947.2 11311.7 11296.4 13631.9 13791 FALSE FALSE TRUE 13736.9483 15891.72728 13048.19628 13318.56235 13672.39804 11054.3935 11629.07586 14740.62036 12136.51468 14270.23622 0.962629356 1.113627485 0.914364421 0.933310573 0.958105937 0.774646847 0.814918245 1.032962603 0.850477489 1 13.8007216 -5.946046366 1.492415978 0.989774763 0.875519692 0.11955352 0.091326012 0.37997626 1.691959495 0.012319936 0.027016862 1.13E-06 5.946046366 -0.114255071 IHAESLLLDS(ph)PAVAK ddPTM_HeLa_Curcumin_4h_R1 2 IHAESLLLDSPAVAK 15 0 Q9H4L5-5;Q9H4L5;Q9H4L5-6;Q9H4L5-2 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 0 IHAESLLLDS(1)PAVAK;IHAESLLLDS(1)PAVAK ; 131.82 0.00032532 52964000 9907.8 7943.5 8266.7 8912.8 9436.5 11321.3 7041.2 5243 10114.8 8453.5 TRUE FALSE FALSE 9123.587175 8630.100744 8573.071174 8875.921195 9323.975901 8973.134763 7238.757122 6841.566564 9005.231746 8747.258496 1.043022472 0.986606346 0.980086638 1.014708917 1.065931218 1.025822521 0.827545811 0.782138377 1.029491897 1 13.09461521 -4.717229489 4.735433512 1.018817726 0.795404168 0.920264041 0.025216263 0.039280448 1.909425399 0.003926341 0.015216237 1.92E-05 4.717229489 -0.223413557 IHDENLR ddPTM_HeLa_Curcumin_4h_R1 2 IHDENLR 7 0 O95232;J3KPP4;D6RDI2 O95232 LUC7L3 Luc7-like protein 3 0 0 ; ; 211.23 2.38E-07 17724100 2055.18 1792.68 1842.71 2009.25 2044.8 2309.6 1644.97 1909.41 2128.8 1806.65 FALSE FALSE TRUE 1892.510334 1947.631271 1911.002454 2000.936256 2020.417096 1830.562925 1691.123431 2491.580319 1895.275966 1869.430953 1.012345672 1.041831081 1.022237516 1.070345098 1.08076583 0.979208632 0.904619359 1.332801468 1.01382507 1 10.86838347 -4.249345264 24.96760168 1.011893881 1.332801668 0.806964892 0.046781058 600.0444212 1238734.913 0.006449607 0.146785976 5.63E-05 4.249345264 0.320907787 IHEDIFDIIDR ddPTM_HeLa_Curcumin_4h_R1 1 IHEDIFDIIDR 11 0 K7EKE5;K7EIS0;Q9NRH3;P23258 K7EKE5 TUBG1;TUBG2 Tubulin gamma chain;Tubulin gamma-2 chain;Tubulin gamma-1 chain 0 0 120.03 0.0033485 4593600 1813 1898.5 2082.5 2129.7 2115.9 3569.8 2457.1 2222.8 2216.7 1949.5 FALSE FALSE TRUE 1669.499137 2062.59788 2159.679282 2120.887866 2090.669274 2829.38324 2526.039613 2900.521487 1973.533556 2017.24498 0.82761348 1.022482594 1.070608331 1.051378433 1.036398303 1.402597735 1.25222253 1.437862786 0.978331128 1 10.97817058 -5.372158311 0.746859768 0.925356647 1.441403308 0.781516687 0.086256288 0.332457103 0.283587409 0.017251335 0.105589044 4.24E-06 5.372158311 0.516046661 IHEGCEEPATHNALAK ddPTM_HeLa_Curcumin_4h_R1 2 IHEGCEEPATHNALAK 16 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 ; ; 90.861 0.0028667 14916700 10464.6 7991.9 9321.7 9624.6 8818.6 10096.7 7126.1 5670.9 9505.5 8991.3 FALSE FALSE TRUE 9636.315868 8682.684225 9667.170402 9584.775955 8713.443955 8002.530607 7326.039187 7399.931304 8462.770432 9303.747006 1.035745691 0.933245951 1.039062046 1.030205997 0.936552117 0.860140608 0.787428891 0.79537108 0.90960883 1 13.18359615 -5.262558708 1.710711916 1.01313015 0.789466922 0.755599489 0.044697099 0.082005859 0.453139058 0.004606875 0.015809456 5.46E-06 5.262558708 -0.223663228 IHFPLATYAPVISAEK ddPTM_HeLa_Curcumin_4h_R1 3 IHFPLATYAPVISAEK 16 0 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;A0A1W2PQM2;P0DPH7-2;F8VVB9;Q6PEY2;C9JDS9;P68363;P68363-2;P68366-2;P68366 Q9BQE3;P68363;P68366-2 TUBA1C;TUBA1B;TUBA3E;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 0 ;; ;; 144.88 0.00077689 31782400 10909.86 8689.93 10184.39 9560.91 9384.28 14412.55 10020.17 9261.12 9814.13 8606.7 FALSE FALSE TRUE 10046.33307 9441.048828 10561.83245 9521.349488 9272.37859 11423.22467 10301.309 12084.79286 8737.544493 8905.782184 1.128068581 1.060103271 1.185952254 1.069119959 1.041163864 1.282675057 1.156698961 1.356960299 0.981109162 1 13.12052661 -1 0.255737783 1.038742425 2.798529598 0.622760213 0.071118407 25.36519365 0.318270703 0.036617059 19.58498648 0.1 1 1.759787172 ALS(ph)PAELR ddPTM_HeLa_Curcumin_4h_R1 2 ALSPAELR 8 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 ALS(1)PAELR;ALS(1)PAELR ; 105.2 0.012699 56505000 9367 8066.4 7986.3 8819.6 7445.2 10849.1 5873.2 2881.7 10814.1 7830.8 TRUE FALSE FALSE 8625.592066 8763.623673 8282.279303 8783.106832 7356.420853 8598.874365 6037.986185 3760.317064 9627.820286 8102.919717 1.064504199 1.081538998 1.02213518 1.08394346 0.907872854 1.061206906 0.745161793 0.464069397 1.188191494 1 12.98422613 -4.457859858 2.044867239 1.032502166 0.407015693 0.871028827 0.072148942 0.086881271 0.525169884 0.007276533 0.08621125 3.48E-05 4.457859858 -0.625486473 down IHGVGFK ddPTM_HeLa_Curcumin_4h_R1 2 IHGVGFK 7 0 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2;B8ZZK4 H7C2W9 RPL31 60S ribosomal protein L31 0 0 ; ; 82.263 0.013554 8775300 19624.8 15051.1 17203.4 17371.5 18559.4 19934.5 15107.8 15447.1 17638.8 16467.4 FALSE FALSE TRUE 18071.47637 16352.05002 17840.97314 17299.62134 18338.09128 15799.85999 15531.68421 20156.84968 15703.86777 17039.64092 1.060555 0.959647571 1.047027529 1.015257388 1.076201744 0.92724137 0.911503023 1.182938641 0.921607905 1 14.05660731 -5.293240705 24.97296042 1.027044709 0.997655095 0 0.081962545 2001.723604 1571909.954 0.010054082 0.022483207 5.09E-06 5.293240705 -0.029389614 IHGVGFK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 IHGVGFKK 8 1 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2;B8ZZK4 H7C2W9 RPL31 60S ribosomal protein L31 0 1 IHGVGFK(1)K 86.794 0.0064771 5353600 6589.2 4949.1 4907.2 4506.4 5233.8 7162.4 4778.3 3763.8 7250 5263.3 FALSE TRUE FALSE 6067.657867 5376.878151 5089.065149 4487.753711 5171.390353 5676.837503 4912.366238 4911.365294 6454.693139 5446.199283 1.114108675 0.98727165 0.93442507 0.824015699 0.949541154 1.042348472 0.901980626 0.901796838 1.185173881 1 12.41103406 -6.969628466 3.815306959 1.053976588 0.92702904 0.521105127 0.070503116 0.156363628 4.955745148 0.011040018 0.014415848 1.07E-07 6.969628466 -0.126947548 IHLGSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 IHLGSSPK 8 0 Q9H410-4;Q9H410;Q5JW53 Q9H410-4 DSN1 Kinetochore-associated protein DSN1 homolog 1 0 IHLGS(0.203)S(0.797)PK 94.309 0.0086861 192120000 7711.7 5431.1 5679.3 5363.7 6678.1 8078.2 5915.5 4418.7 6671.9 5423.2 TRUE FALSE FALSE 7101.310808 5900.540083 5889.779854 5341.506431 6598.468019 6402.69026 6081.473009 5765.941289 5940.009262 5611.655796 1.265457303 1.051479331 1.049561853 0.951859242 1.175850455 1.140962755 1.083721673 1.027493756 1.058512759 1 12.45421081 IHLMQNGKR ddPTM_HeLa_Curcumin_4h_R1 1 IHLMQNGKR 9 1 J3KQA0;Q8N9I0;P21579 J3KQA0 SYT1;SYT2 Synaptotagmin-2;Synaptotagmin-1 0 0 32.841 0.019146 2434100 3074.8 2488.3 2790.7 4029.3 2360.5 2777.4 2381.8 1673 3292.3 3051.6 FALSE FALSE TRUE 2831.426335 2703.377564 2894.125797 4012.627824 2332.352579 2201.335932 2448.626898 2183.089998 2931.142927 3157.642873 0.896689857 0.856137845 0.91654627 1.27076683 0.738637228 0.697145314 0.775460366 0.691366974 0.928269296 1 11.6246323 -5.571692394 24.99999672 0.961057274 0.725261223 0.557562677 0.109591677 65.87941919 33740.04676 0.015769916 0.031539838 2.68E-06 5.571692394 -0.235796051 IHPMAYQLQLQAAS(ph)NFKSPVK ddPTM_HeLa_Curcumin_4h_R1 1 IHPMAYQLQLQAASNFKSPVK 21 1 Q5SRQ6;P67870 Q5SRQ6 CSNK2B Casein kinase II subunit beta 1 0 IHPMAYQLQLQAAS(0.552)NFKS(0.448)PVK 69.98 0.0014068 62239000 1103.5 808.75 807.82 735.77 839.84 3212.8 1803.2 1213.5 1243.2 1103.3 TRUE FALSE FALSE 1016.156811 878.6547463 837.7585198 732.7255787 829.8254565 2546.429064 1853.792939 1583.490564 1106.82407 1141.639593 0.890085467 0.769642847 0.733820485 0.641818647 0.726871652 2.23050171 1.623798746 1.387031926 0.969503929 1 10.15689156 -5.2761785 24.99989487 0.880447703 1.734779605 0.77564509 0.227070303 283.434572 480749.8891 0.033407679 0.074996799 5.29E-06 5.2761785 0.854331902 IHPMAYQLQLQAASNFKS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 2 IHPMAYQLQLQAASNFKSPVK 21 1 Q5SRQ6;P67870 Q5SRQ6 CSNK2B Casein kinase II subunit beta 1 0 IHPMAYQLQLQAAS(0.015)NFKS(0.985)PVK;IHPMAYQLQLQAAS(0.228)NFKS(0.772)PVK ; 66.401 0.0030734 189233000 3744.5 3873 3176.6 2982.3 2392.03 11896.3 5459.4 5522 4806.4 3996.5 TRUE FALSE FALSE 3448.118874 4207.764862 3294.32759 2969.960033 2363.506605 9428.873281 5612.576071 7205.63238 4279.149945 4135.378078 0.833809826 1.017504272 0.796620654 0.718183435 0.571533379 2.280051087 1.357209901 1.74243618 1.034766318 1 12.01380352 -5.270453379 24.9924846 0.881777121 1.749630153 0.747261923 0.24975247 228.3856138 633229.1257 0.033360266 0.075617605 5.36E-06 5.270453379 0.867853032 IHQDSES(ph)GDELSSSSTEQIR ddPTM_HeLa_Curcumin_4h_R1 2 IHQDSESGDELSSSSTEQIR 20 0 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 0 IHQDS(0.002)ES(0.998)GDELSSSSTEQIR;IHQDSES(1)GDELSSSSTEQIR ; 208.44 4.93E-14 29435500 5106.4 4913.3 4158.3 4591.8 5663.7 6811.4 3908.3 3204.8 6200.4 5111.5 TRUE FALSE FALSE 4702.223052 5337.983759 4312.410256 4572.800348 5596.164077 5398.63886 4017.956379 4181.928767 5520.231633 5289.124245 0.889036225 1.009237732 0.815335405 0.864566635 1.058051166 1.020705623 0.75966383 0.790665633 1.043694831 1 12.36881315 -1.000001855 0.019492523 1.62137828 8.29E-08 0.22997167 0.094521273 4393.111647 6.668198036 208.0472037 368.1783912 0.099999573 1.000001855 -1.621378197 IHRAS(ph)DPGLPAEEPK ddPTM_HeLa_Curcumin_4h_R1 2 IHRASDPGLPAEEPK 15 1 P27708;F8VPD4 P27708 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 0 IHRAS(1)DPGLPAEEPK;IHRAS(1)DPGLPAEEPK ; 113.23 0.00082567 321420000 10968.1 9266.9 10510 11248.8 12220 10413.9 5825.2 3622.4 8867 9209.3 TRUE FALSE FALSE 10099.96331 10067.88954 10899.50985 11202.25545 12074.28448 8253.939751 5988.639434 4726.853085 7894.312284 9529.32249 1.059882623 1.056516825 1.14378644 1.175556338 1.267066415 0.866162286 0.628443359 0.49603244 0.828423248 1 13.21815793 -4.838470814 2.765887826 1.065171488 0.533795138 0.764733426 0.113351417 0.079414593 1.197062919 0.013710418 0.055789764 1.45E-05 4.838470814 -0.531376349 TLLSESSSQSSKS(ph)PSLSSK ddPTM_HeLa_Curcumin_4h_R1 1 TLLSESSSQSSKSPSLSSK 19 1 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 0 TLLSES(0.001)S(0.001)S(0.001)QS(0.044)S(0.012)KS(0.47)PS(0.367)LS(0.084)S(0.02)K 80.41 0.0019243 287430000 3853.5 2721.3 3090.3 3347.3 2847.8 3058.4 2243.2 523.92 3824.9 3476.7 TRUE FALSE FALSE 3548.491409 2956.517046 3204.829237 3333.44976 2813.841845 2424.053365 2306.138155 683.6607962 3405.318039 3597.515066 0.986372911 0.821822005 0.890845258 0.926597859 0.78216263 0.673813263 0.641036413 0.190036952 0.94657506 1 11.81278501 -4.457658129 0.630182894 0.981003854 6.99E-25 0.885308993 0.0781536 0.579625447 0.182090795 0.013586013 0.389161167 3.49E-05 4.457658129 -0.981003854 down IHS(ph)PIIR ddPTM_HeLa_Curcumin_4h_R1 3 IHSPIIR 7 0 O60885 O60885 BRD4 Bromodomain-containing protein 4 1 0 IHS(1)PIIR;IHS(1)PIIR;IHS(1)PIIR ;; 90.601 0.011998 93589000 4525.8 3505.46 3905.3 4484 3860.3 4226.9 3013.87 3583.7 4293.9 4094.6 TRUE FALSE FALSE 4167.578154 3808.456342 4050.033853 4465.446396 3814.268444 3350.193293 3098.431081 4676.353633 3822.869913 4236.887045 0.983641553 0.898880782 0.955898472 1.053945113 0.900252568 0.790720465 0.731298958 1.103723933 0.902282707 1 12.04878895 -5.562889928 7.885492269 0.984960269 0.85827352 0.125027707 0.100506658 0.212553226 36.08710876 0.013044345 0.026257932 2.74E-06 5.562889928 -0.126686749 IHTDFEK ddPTM_HeLa_Curcumin_4h_R1 1 IHTDFEK 7 0 J3KQ32;Q9NTK5-2;Q9NTK5 J3KQ32 OLA1 Obg-like ATPase 1 0 0 133.81 0.00019027 0 6184.5 4769.6 5845.3 5194.1 5723.7 7061.5 4915.3 4821.1 6511.2 5387 FALSE FALSE TRUE 5694.990299 5181.862971 6061.93196 5172.60819 5655.448616 5596.8653 5053.210089 6291.031196 5796.93765 5574.197849 1.021669925 0.929615904 1.087498529 0.927955615 1.014576226 1.004066496 0.906535833 1.128598476 1.039959077 1 12.44454849 IHVFYIDYGNR ddPTM_HeLa_Curcumin_4h_R1 3 IHVFYIDYGNR 11 0 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 0 ;; ;; 106.62 0.0016199 18062500 5122.3 3007.05 4169.5 2651.16 3214.56 17778.5 10051.8 8545.8 4748.8 4204.2 FALSE FALSE TRUE 4716.86455 3266.966003 4324.025338 2640.190202 3176.228471 14091.0387 10333.82645 11151.37508 4227.868521 4350.295637 1.084262989 0.750975629 0.993961261 0.60689903 0.730117844 3.239099103 2.375430848 2.563360289 0.971857748 1 12.08689773 -5.267838578 24.99997809 0.963739037 2.690910178 0.915171087 0.256964997 100.752836 393615.2552 0.036694595 0.083941483 5.40E-06 5.267838578 1.727171141 IIALDGDTK ddPTM_HeLa_Curcumin_4h_R1 2 IIALDGDTK 9 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 0 ; ; 117.89 0.0015135 23093000 15100.2 10732.1 14276.7 12993.2 13716.7 18042.4 13167.4 13179.5 13723.7 10696.1 FALSE FALSE TRUE 13905.00324 11659.7349 14805.80706 12939.43758 13553.13731 14300.20286 13536.84181 17197.86888 12218.24445 11067.78868 1.256348819 1.053483694 1.337738503 1.169107756 1.224556929 1.292056008 1.223084592 1.553866755 1.103946308 1 13.43407938 -8.128188112 0.037192435 4.22E-17 2.305779292 0.514064361 0.10434008 66.1438727 1.308130832 42.92718711 37.74165118 7.44E-09 8.128188112 2.305779292 IIAPPERK ddPTM_HeLa_Curcumin_4h_R1 2 IIAPPERK 8 1 P60709;P63267-2;Q562R1;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 0 0 ; ; 78.77 0.013432 310690000 10527.3 7180.9 9080.8 8066.3 8918 8876 8316.2 9084.2 9054.6 9685.6 FALSE FALSE TRUE 9694.053097 7801.584999 9417.342436 8032.923788 8811.658675 7035.017547 8549.53019 11853.93076 8061.333033 10022.17388 0.967260518 0.778432413 0.939650674 0.801515109 0.879216304 0.70194527 0.853061451 1.182770415 0.804349748 1 13.29090785 -7.435284538 7.998099776 0.985655375 0.868637908 0 0.1332633 0.393627033 32.46588414 0.019735158 0.022485589 3.67E-08 7.435284538 -0.117017468 IIAPSRGS(ph)PLPVLSWANR ddPTM_HeLa_Curcumin_4h_R1 1 IIAPSRGSPLPVLSWANR 18 1 I3L1Q9;I3L413;C9J2U0;P24864-2;P24864-3;P24864 I3L1Q9 CCNE1 G1/S-specific cyclin-E1 1 0 IIAPS(0.079)RGS(0.921)PLPVLSWANR 55.621 0.016003 7088900 1289.2 1177.3 1433.3 1148.7 1283.7 1683.4 1392.7 965.18 1570 1702.2 TRUE FALSE FALSE 1187.15846 1279.060566 1486.419359 1143.946984 1268.392716 1334.243864 1431.775414 1259.458939 1397.774928 1761.351323 0.674004353 0.726181398 0.843908503 0.649471215 0.72012477 0.757511489 0.812884627 0.715052654 0.793580991 1 10.78246699 -9.351874255 0.974018703 1.006727693 0.735772713 0.253198945 0.082923785 0.225412399 0.367520351 0.044195824 0.010453685 4.45E-10 9.351874255 -0.27095498 IIDDSEITKEDDALWPPPDR ddPTM_HeLa_Curcumin_4h_R1 2 IIDDSEITKEDDALWPPPDR 20 1 F5H6N1;P61326;Q96A72;F5H3U9;F5H6P7 F5H6N1 MAGOHB;MAGOH Protein mago nashi homolog;Protein mago nashi homolog 2 0 0 ; ; 108.34 0.00024373 15089700 2511.8 2401.2 2615 2926.2 2189.26 3159.9 2263.6 2244.7 3495.8 2580.8 FALSE FALSE TRUE 2312.98838 2608.749028 2711.9142 2914.09216 2163.154504 2504.501121 2327.110524 2929.098697 3112.319486 2670.482608 0.866131228 0.976882988 1.015514646 1.091223044 0.810023813 0.937845883 0.871419464 1.096842454 1.165452071 1 11.38288477 -4.24342897 23.8292958 0.942176368 1.096842704 0.060868011 0.105007635 2350.374354 3109650.866 0.011449761 0.463484343 5.71E-05 4.24342897 0.154666336 IIDEVVNK ddPTM_HeLa_Curcumin_4h_R1 1 IIDEVVNK 8 0 O95816-2;O95816 O95816-2 BAG2 BAG family molecular chaperone regulator 2 0 0 109.86 0.0065783 2243000 3640.5 2967.4 3627.2 3639.7 3646.7 2877.6 2721.1 2463.4 3880.1 3177.1 FALSE FALSE TRUE 3352.350584 3223.888834 3761.627223 3624.639886 3603.215484 2280.753323 2797.446743 3214.47932 3454.462738 3287.503989 1.019725176 0.980649406 1.14421982 1.102550719 1.096033799 0.693764428 0.850933338 0.9777872 1.05078587 1 11.68277693 -5.277657543 24.99933512 1.0298622 0.84183881 0.57987301 0.081905371 465.7575074 717936.9311 0.011921594 0.026731719 5.28E-06 5.277657543 -0.18802339 YSEEGLS(ph)PSKR ddPTM_HeLa_Curcumin_4h_R1 1 YSEEGLSPSKR 11 1 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 0 YSEEGLS(0.895)PS(0.105)KR 109.39 0.010931 21009000 2351.6 2361.1 2624.5 2783.2 2569.1 2765.3 1776.6 868.97 2912.2 2689.4 TRUE FALSE FALSE 2165.468379 2565.182963 2721.766279 2771.683856 2538.46516 2191.745609 1826.446615 1133.914953 2592.738946 2782.85645 0.778145915 0.921780555 0.978047674 0.995985207 0.9121797 0.787588454 0.656320815 0.407464407 0.931682605 1 11.44235078 -4.457402475 1.36815537 0.909951399 0.303772903 0.870675279 0.063987185 0.335288496 0.710139579 0.013592765 0.252267035 3.49E-05 4.457402475 -0.606178496 down IIEDQQESLNK ddPTM_HeLa_Curcumin_4h_R1 1 IIEDQQESLNK 11 0 P05455 P05455 SSB Lupus La protein 0 0 215.56 1.99E-30 2673500 1104.4 1073.7 1167.7 1252.1 1058.8 1363.9 1107.9 903.69 1638.5 1162.2 FALSE FALSE TRUE 1016.985575 1166.505844 1210.975989 1246.919142 1046.174502 1081.011766 1138.984692 1179.220921 1458.760649 1202.586363 0.845665314 0.969997564 1.006976319 1.036864528 0.869937107 0.898905724 0.947112596 0.980570674 1.21301945 1 10.23192479 -4.318041955 4.186941686 0.936328696 0.9820562 0 0.105311155 0.675433094 22.16090776 0.010090114 0.07884524 4.81E-05 4.318041955 0.045727504 IIEEDDAYDFSTDYV ddPTM_HeLa_Curcumin_4h_R1 1 IIEEDDAYDFSTDYV 15 0 Q9BVP2-2;Q9BVP2 Q9BVP2-2 GNL3 Guanine nucleotide-binding protein-like 3 0 0 123.86 0.0087968 1594500 1868.3 1597.6 1532.6 1634 1613.6 2127.6 1648.8 1349.2 1798.7 1287.1 FALSE FALSE TRUE 1720.422084 1735.689425 1589.399504 1627.238941 1594.358874 1686.311777 1695.06089 1760.564869 1601.38711 1331.826629 1.291776306 1.303239766 1.193398202 1.221809885 1.197121937 1.266164634 1.272733893 1.321917456 1.202399077 1 10.37919058 -9.271673529 0.849198678 0.988700552 1.25741131 0.289609195 0.073875968 0.214206695 0.258969716 0.038161352 0.008828646 5.35E-10 9.271673529 0.268710758 IIELPFQNK ddPTM_HeLa_Curcumin_4h_R1 2 IIELPFQNK 9 0 P36952 P36952 SERPINB5 Serpin B5 0 0 ; ; 127.46 0.00078409 1584060 4041.1 2856.47 3401.56 2812.76 3358.42 6351.9 4006.06 4080.21 2966.45 3182.42 FALSE FALSE TRUE 3721.242671 3103.370539 3527.624806 2801.121544 3318.373035 5034.444339 4118.459262 5324.247246 2641.037857 3293.008858 1.130043322 0.94241184 1.07124668 0.850626787 1.007702432 1.528828059 1.250667532 1.616833563 0.80201359 1 11.68519068 -5.266362294 24.99341164 1.03501977 1.443965508 0.724176645 0.135511075 151.3880286 768591.7681 0.016107866 0.037098812 5.42E-06 5.266362294 0.408945738 IIEQLS(ph)PQAATSR ddPTM_HeLa_Curcumin_4h_R1 1 IIEQLSPQAATSR 13 0 Q03468;P0DP91;D6R9X7 Q03468 ERCC6 DNA excision repair protein ERCC-6 1 0 IIEQLS(0.99)PQAAT(0.005)S(0.005)R 160.79 0.00025282 15561000 1934.7 1486.7 1460 1675.2 1640.8 2327.8 1673.9 717.5 1939.9 1319.2 TRUE FALSE FALSE 1781.566454 1615.203723 1514.108884 1668.268466 1621.234532 1844.98804 1720.865129 936.262447 1727.097823 1365.042102 1.305136634 1.183262935 1.109203066 1.222137005 1.187680973 1.351597902 1.26066817 0.685885399 1.265234106 1 10.41472973 -4.255228112 24.80590219 1.174833192 0.685885157 0.69999046 0.100554698 367.6164996 1468102.048 0.018086615 0.223763766 5.56E-05 4.255228112 -0.488948035 IIETEDQIDK ddPTM_HeLa_Curcumin_4h_R1 1 IIETEDQIDK 10 0 G3V599;Q96PC5-2;Q96PC5 G3V599 MIA2 Melanoma inhibitory activity protein 2 0 0 161.02 0.0051877 11745000 1554.5 1208.3 1583.4 1345.6 1558.1 1732.6 1373.9 1208.7 1443.1 1157.1 FALSE FALSE TRUE 1431.459685 1312.740068 1642.082197 1340.032264 1539.520675 1373.23923 1412.447936 1577.227066 1284.79554 1197.309139 1.195563984 1.096408626 1.37147721 1.119203237 1.285817192 1.1469379 1.179685255 1.317309803 1.073069184 1 10.22557998 -9.330988432 0.407586218 0.927958516 1.227447269 0.411830605 0.084899023 1.429172911 0.29991951 0.18628743 0.025697818 4.67E-10 9.330988432 0.299488753 IIEVVDAIMTTAQSHQR ddPTM_HeLa_Curcumin_4h_R1 1 IIEVVDAIMTTAQSHQR 17 0 Q01813;Q01813-2;Q5VSR5 Q01813 PFKP "ATP-dependent 6-phosphofructokinase, platelet type" 0 0 109.1 0.0047509 3996600 1625.3 1716.2 1795.8 1557.3 1661.4 1943.6 1787.7 1659.5 1824.5 1648.7 FALSE FALSE TRUE 1496.65579 1864.540681 1862.353928 1550.856305 1641.58889 1540.475451 1837.858051 2165.473911 1624.356915 1705.992202 0.877293453 1.092936227 1.09165442 0.909064123 0.962248765 0.902979187 1.077295692 1.269334003 0.952147913 1 10.73639534 -4.3948643 2.806273352 0.959518618 1.285907371 0.611166667 0.071148222 0.176552301 2.175558759 0.011224481 0.111890186 4.03E-05 4.3948643 0.326388753 IIFEDDR ddPTM_HeLa_Curcumin_4h_R1 1 IIFEDDR 7 0 D6RC06;D6REP8;D6RE99;D6RD60;P49773 D6RC06 HINT1 Histidine triad nucleotide-binding protein 1 0 0 101.69 0.019901 8190600 6081.7 5612.6 6005.8 5815.8 5809.9 7628.5 5647.1 6009.4 6097.8 5424 FALSE FALSE TRUE 5600.327028 6097.728135 6228.380231 5791.735761 5740.620737 6046.263109 5805.542428 7841.638396 5428.886596 5612.483596 0.997834013 1.086458077 1.109736915 1.031938118 1.022830738 1.077288335 1.034398111 1.397177963 0.967287744 1 12.45442361 -4.25839928 5.095397773 1.022363307 1.415365484 0.858701865 0.043591843 0.046941667 3.904980702 0.006599378 0.064538485 5.52E-05 4.25839928 0.393002177 IIFVVGGPGSGK ddPTM_HeLa_Curcumin_4h_R1 2 IIFVVGGPGSGK 12 0 P00568;Q5T9B7 P00568 AK1 Adenylate kinase isoenzyme 1 0 0 ; ; 167.67 1.58E-06 7811600 5246.7 4404.7 4556.6 4449.3 4896 6125.6 4899.5 5695.1 4957.7 4940.9 FALSE FALSE TRUE 4831.418159 4785.422641 4725.471604 4430.889976 4837.618398 4855.08151 5036.966784 7431.509773 4413.852714 5112.595907 0.945002939 0.93600643 0.924280285 0.866661488 0.946215677 0.949631381 0.985207295 1.453568776 0.863329079 1 12.31984029 -4.260725838 4.655123269 0.95653077 1.483990696 0.921213167 0.045172081 0.035110747 2.040764492 0.005916435 0.060148382 5.49E-05 4.260725838 0.527459926 DRPGS(ph)PESPLLDAPFSR ddPTM_HeLa_Curcumin_4h_R1 4 DRPGSPESPLLDAPFSR 17 1 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 0 DRPGS(1)PESPLLDAPFSR;DRPGS(0.998)PES(0.002)PLLDAPFSR;DRPGS(1)PESPLLDAPFSR;DRPGS(0.997)PES(0.003)PLLDAPFSR ;;; 166.36 0.00015003 81709500 6242.4 5191.4 5523.5 5775.8 5473.1 5538.1 3772.6 2003.98 6371.4 5740.7 TRUE FALSE FALSE 5748.307453 5640.121484 5728.205769 5751.90127 5407.836857 4389.435633 3878.449003 2614.984277 5672.47336 5940.188898 0.967697754 0.949485207 0.964313739 0.968302754 0.910381294 0.738938729 0.652916779 0.440219044 0.954931477 1 12.53629309 -4.457169322 0.789416775 0.984072441 0.220965144 0.981571743 0.0237794 0.165711237 0.088001868 0.003827025 0.104040272 3.49E-05 4.457169322 -0.763107298 down IIGEDS(ph)PSRLDR ddPTM_HeLa_Curcumin_4h_R1 2 IIGEDSPSRLDR 12 1 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 IIGEDS(0.958)PS(0.042)RLDR;IIGEDS(0.986)PS(0.014)RLDR ; 87.363 0.0077165 378770000 7695.6 6578.7 6628 6297.9 5759.8 7197.9 6364.7 1790.36 7026 5359.7 TRUE FALSE FALSE 7086.48514 7147.333514 6873.639511 6271.840959 5691.118147 5704.974403 6543.276352 2336.232522 6255.265378 5545.949176 1.277776791 1.28874847 1.239398215 1.130886844 1.026175676 1.028674123 1.179829844 0.421250258 1.127898071 1 12.43721868 -4.259501975 24.92481689 1.139916757 0.421250004 0.827947516 0.098873931 64.50515337 829795.3984 0.017801076 0.155313081 5.50E-05 4.259501975 -0.718666753 IIGEDSPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 IIGEDSPSR 9 0 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 IIGEDS(0.332)PS(0.668)R 126.66 0.0045109 54311000 4191.8 2935.5 3051.7 2973.2 3625.7 3907.1 3152.5 1289.5 3500.2 2827.1 TRUE FALSE FALSE 3860.014607 3189.23154 3164.798687 2960.897686 3582.465896 3096.723418 3240.950665 1682.662614 3116.236817 2925.341515 1.319509051 1.09020828 1.081856143 1.012154537 1.224631681 1.058585263 1.107887968 0.575202111 1.065255732 1 11.51438934 -4.255230223 4.420231344 1.133731522 0.533257197 0.732946502 0.09510028 0.104517778 4.936840181 0.017415755 0.196397178 5.56E-05 4.255230223 -0.600474325 IIHDFPQFYPLGIVQHD ddPTM_HeLa_Curcumin_4h_R1 2 IIHDFPQFYPLGIVQHD 17 0 B5MC59;P35244 B5MC59 RPA3 Replication protein A 14 kDa subunit 0 0 ; ; 99.915 0.0017544 12681200 2893 2455.5 3022.2 2351.4 2556.89 4972.8 3373.5 3167.5 3427.2 2981.6 FALSE FALSE TRUE 2664.015997 2667.742479 3134.205391 2341.67053 2526.400757 3941.385225 3468.151331 4133.256169 3051.244734 3085.210378 0.863479527 0.86468738 1.015880607 0.758998656 0.818874711 1.277509389 1.124121504 1.339699943 0.988990818 1 11.59115315 -5.255633989 24.98909528 0.914567733 1.234811421 0.741963232 0.093078307 198.126824 852826.7446 0.01363606 0.033773593 5.55E-06 5.255633989 0.320243687 IIHEDGYSEEECR ddPTM_HeLa_Curcumin_4h_R1 1 IIHEDGYSEEECR 13 0 P04899-6;P04899-3;P04899-5;P04899-2;P04899;P04899-4 P04899-6 GNAI2 Guanine nucleotide-binding protein G(i) subunit alpha-2 0 0 116.98 0.0022233 4892000 4321.5 4011.5 3437.8 4295.9 4901.3 7224.7 4086.9 21573 7025 5380.6 FALSE FALSE TRUE 3979.448715 4358.236185 3565.207892 4278.124704 4842.855199 5726.215781 4201.567415 28150.50839 6254.375076 5567.57545 0.71475434 0.782788886 0.640351967 0.768399951 0.869831984 1.028493611 0.75464939 5.056152116 1.12335704 1 12.44283349 -4.260723345 24.99647127 0.841483161 5.056153421 0.986763659 0.146012831 4.330612846 151149.6261 0.019555709 0.157217728 5.49E-05 4.260723345 4.214670259 IIIEELSLVAAS(ph)PTLSPR ddPTM_HeLa_Curcumin_4h_R1 2 IIIEELSLVAASPTLSPR 18 0 Q16513-3;Q16513-2;Q16513;Q16513-4;B1AL79;H0Y5V5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 0 IIIEELSLVAAS(0.952)PT(0.048)LSPR;IIIEELS(0.009)LVAAS(0.715)PT(0.058)LS(0.218)PR ; 352.77 2.81E-174 448970000 4326.4 3715.6 3593.5 3372.4 3582.9 4758 3775.4 3532.9 3873.3 3124.6 TRUE FALSE FALSE 3983.960875 4036.759908 3726.678271 3358.445902 3540.176258 3771.137166 3881.327563 4610.064947 3448.408681 3233.179617 1.232211428 1.248541803 1.152635706 1.038743992 1.094951929 1.166386534 1.200467658 1.425861069 1.066568854 1 11.65873794 -9.338018605 0.995843009 0.996907186 1.188813148 0.288542748 0.099324121 0.537316759 0.929913795 0.074826105 0.018458675 4.59E-10 9.338018605 0.191905961 IIIEELSLVAASPT(ph)LSPR ddPTM_HeLa_Curcumin_4h_R1 1 IIIEELSLVAASPTLSPR 18 0 Q16513-3;Q16513-2;Q16513;Q16513-4;B1AL79;H0Y5V5 Q16513-3 PKN2 Serine/threonine-protein kinase N2 1 0 IIIEELSLVAAS(0.043)PT(0.954)LS(0.003)PR 268.17 2.70E-53 15410000 1569 1079.9 1423 963.88 1222 1938.9 1291.6 1794.8 1533.1 1371.6 TRUE FALSE FALSE 1444.811994 1173.241744 1475.737632 959.89172 1207.428448 1536.750284 1327.83882 2342.026258 1364.922766 1419.262998 1.018001594 0.826655627 1.039791521 0.676331111 0.850743273 1.08278049 0.935583343 1.65017073 0.961712359 1 10.47092624 -4.259812593 24.7893093 0.967266441 1.650170987 0.762165738 0.118859589 48.50436356 739042.3503 0.016725997 0.142493741 5.50E-05 4.259812593 0.682904546 IIILYDDDER ddPTM_HeLa_Curcumin_4h_R1 1 IIILYDDDER 10 0 Q9BYV8-5;Q9BYV8-2;Q9BYV8 Q9BYV8-5 CEP41 Centrosomal protein of 41 kDa 0 0 179.37 0.0027335 2032400 1175.5 1008.9 1260 973.36 1087.7 1267.6 1071.9 1135.5 1322.1 1186.2 FALSE FALSE TRUE 1082.457935 1096.10482 1306.696708 969.3324942 1074.729888 1004.685471 1101.974629 1481.708723 1177.068938 1227.420362 0.881896674 0.893015021 1.064587772 0.789731476 0.875600504 0.818534141 0.897797253 1.207173002 0.958977849 1 10.26141371 -9.481611163 1.210121214 1.000217133 0.916734241 0.017733197 0.117139619 1.134332741 2.959954084 0.078830943 0.019089067 3.30E-10 9.481611163 -0.083482892 IIIPEIQK ddPTM_HeLa_Curcumin_4h_R1 2 IIIPEIQK 8 0 P55060-4;P55060-3;P55060 P55060-4 CSE1L Exportin-2 0 0 ; ; 98.392 0.014888 1981240 5180.1 3996.6 5078.2 5243.5 4618.8 4745 3955.5 3776.7 4969 4911.1 FALSE FALSE TRUE 4770.089619 4342.048295 5266.402559 5221.803786 4563.723827 3760.833513 4066.480684 4928.198444 4423.913132 5081.760359 0.938668745 0.85443783 1.036334299 1.027558054 0.89805963 0.740065105 0.800211029 0.969781748 0.870547373 1 12.31111263 -5.52501937 11.9440059 0.969358103 0.830698651 0.303351041 0.078238183 0.090924741 411.8894304 0.010390586 0.021260454 2.99E-06 5.52501937 -0.138659451 IILDLISES(ph)PIK ddPTM_HeLa_Curcumin_4h_R1 1 IILDLISESPIK 12 0 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 0 IILDLISES(1)PIK 181.76 8.19E-05 224300000 625.92 466.23 461.88 540.54 604.08 775.51 607.19 551.49 545.71 446.78 TRUE FALSE FALSE 576.3777715 506.5288437 478.9976791 538.3033887 596.8767405 614.6604842 624.2261172 719.6367623 485.8469783 462.3055717 1.246746323 1.095658099 1.036106221 1.164388711 1.291087058 1.329554567 1.350245715 1.556625761 1.050921745 1 8.85270294 -1 0.29493481 1.081355057 4.868629588 0.816704967 0.071228077 20.93530835 0.267754022 0.037695342 42.16541646 0.1 1 3.787274531 IILDLISES(ph)PIKGR ddPTM_HeLa_Curcumin_4h_R1 3 IILDLISESPIKGR 14 1 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 0 IILDLIS(0.298)ES(0.702)PIKGR;IILDLIS(0.016)ES(0.984)PIKGR;IILDLIS(0.008)ES(0.992)PIKGR ;; 189.8 6.78E-05 1161489300 2008.21 1641.05 1925.77 1871.03 1846.31 2618.57 2279.45 2060.83 2330.05 1841.12 TRUE FALSE FALSE 1849.258059 1782.89505 1997.14073 1863.288174 1824.293959 2075.449065 2343.405232 2689.16758 2074.449344 1905.098783 0.970688804 0.935854385 1.048313478 0.978053312 0.957584969 1.089418083 1.230070195 1.411563329 1.088893323 1 10.89565009 -4.554594391 1.450616303 0.983875191 1.466857211 0.896755553 0.045136767 0.099032037 0.274159421 0.004448068 0.058747355 2.79E-05 4.554594391 0.48298202 IILLVK ddPTM_HeLa_Curcumin_4h_R1 1 IILLVK 6 0 P52209-2;P52209;K7EMN2;K7EM49;K7EPF6 P52209-2 PGD "6-phosphogluconate dehydrogenase, decarboxylating" 0 0 105.82 0.010853 0 2147 1360 1827.7 1717.2 2162.2 3021.4 2375.9 2006.4 1997.3 2136 FALSE FALSE TRUE 1977.062684 1477.55234 1895.43617 1710.094681 2136.417177 2394.727582 2442.56136 2618.142124 1778.201187 2210.225841 0.89450709 0.668507404 0.857575789 0.773719432 0.966605827 1.08347642 1.105118452 1.184558643 0.804533706 1 11.10997808 -5.23232127 2.572512011 0.905986071 1.137313476 0.58387569 0.099968484 0.210270787 2.720211506 0.016507794 0.047682142 5.86E-06 5.23232127 0.231327406 IINEPTAAAIAYGLDKK ddPTM_HeLa_Curcumin_4h_R1 1 IINEPTAAAIAYGLDKK 17 1 P11142;E9PKE3;P11142-2;E9PN89;E9PI65;P54652 P11142;P54652 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 0 109.87 0.0011614 0 2100.2 1611.6 1864.6 1966.5 1921.5 2677.3 2094 1620.9 1920.1 1791.9 FALSE FALSE TRUE 1933.966954 1750.899523 1933.703716 1958.363144 1898.587367 2121.997801 2152.752004 2115.104948 1709.469834 1854.168392 1.043037387 0.944304482 1.042895416 1.05619487 1.023956279 1.144447187 1.161033709 1.140729697 0.921960401 1 10.85655656 -5.257927421 4.612580261 1.019306534 1.151691526 0.6987846 0.042624046 0.064533391 3.804897233 0.004436123 0.011059259 5.52E-06 5.257927421 0.132384991 IIPELVGS(ph)PTQSTSSR ddPTM_HeLa_Curcumin_4h_R1 1 IIPELVGSPTQSTSSR 16 0 Q9NSI6-3;Q9NSI6-2;Q9NSI6;H7C409 Q9NSI6-3 BRWD1 Bromodomain and WD repeat-containing protein 1 1 0 IIPELVGS(0.916)PT(0.084)QSTSSR 193.3 2.98E-07 15159000 1938.9 1624.8 1964.4 1928 1933.3 1852.1 1632.9 690.49 2171 1704.7 TRUE FALSE FALSE 1785.434019 1765.240472 2037.202392 1920.022447 1910.24666 1467.953583 1678.714779 901.0172224 1932.846732 1763.938198 1.012186266 1.000738276 1.154917102 1.088486234 1.082944211 0.832202389 0.951685712 0.510798634 1.095756492 1 10.7845843 -3.967088794 1.276739696 1.0230486 4.81E-13 0.793649681 0.080048729 0.882668657 0.746296398 0.011181712 1.410324319 0.000107873 3.967088794 -1.0230486 IIPGFMCQGGDFTR ddPTM_HeLa_Curcumin_4h_R1 9 IIPGFMCQGGDFTR 14 0 P62937;F8WE65;C9J5S7;P0DN26;A0A0H2UH34;A0A0B4J2A2;A0A075B767;A0A075B759;Q9Y536;F5H284 P62937 PPIA;PPIAL4C;PPIAL4E;PPIAL4A;PPIAL4D "Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase;Peptidyl-prolyl cis-trans isomerase A-like 4A/B/C;Peptidyl-prolyl cis-trans isomerase A-like 4D" 0 0 ;;;;;;;; ;;;;;;;; 182.46 0.00050255 1587949620 6222.41 4797.765 5610.05 4569.7 5181.15 8335.39 6564.1 5799.71 6340.04 5799.51 FALSE FALSE TRUE 5729.899683 5212.462428 5817.963388 4550.791792 5119.36817 6606.536155 6748.27098 7568.01488 5644.553474 6001.042541 0.954817374 0.868592814 0.969492109 0.758333533 0.8530798 1.100898071 1.124516438 1.261116686 0.940595477 1 12.55099744 -4.899248247 2.361311387 0.94555574 1.210795088 0.669666336 0.080214263 0.16519898 1.801614048 0.012715245 0.052864383 1.26E-05 4.899248247 0.265239348 IIQLIEGK ddPTM_HeLa_Curcumin_4h_R1 1 IIQLIEGK 8 0 A6NF51;O95861-3;O95861-4;O95861;O95861-2 A6NF51 BPNT1 "3(2),5-bisphosphate nucleotidase 1" 0 0 99.139 0.0097493 0 311.06 373.7 223.66 273.34 297.86 514.91 358.93 288.83 297.63 129.04 FALSE FALSE TRUE 286.4392728 406.0009628 231.9490364 272.2089915 294.308214 408.1118618 369.0006098 376.8929374 264.9807336 133.5241304 2.145224776 3.040656109 1.737131975 2.038650173 2.204157504 3.056465229 2.763549994 2.822657869 1.984515704 1 7.060956678 -9.336205187 0.218642237 7.79E-18 2.92436564 0.363159439 0.492734531 3.216428039 0.224537615 2.696372671 0.548805473 4.61E-10 9.336205187 2.92436564 IIQLLDDYPK ddPTM_HeLa_Curcumin_4h_R1 1 IIQLLDDYPK 10 0 F8VWS0;P05388-2;Q8NHW5;P05388;G3V210;F8VU65;F8VS58;F8VQY6;F8VRK7;F8VZS0 F8VWS0 RPLP0;RPLP0P6 60S acidic ribosomal protein P0;60S acidic ribosomal protein P0-like 0 0 123.79 0.0023685 681000 1546.2 1224 1547 1474 1013.9 1602.3 1334.7 1076.7 948.64 291.13 FALSE FALSE TRUE 1423.816638 1329.797106 1604.333181 1467.900979 1001.809905 1269.964918 1372.14809 1404.980873 844.5765654 301.2467458 4.726413341 4.414311937 5.325644851 4.87275298 3.32554598 4.21569672 4.554897634 4.663887305 2.803603946 1 8.234801847 -9.187769091 0.772939869 0.822057389 4.522765262 0.64358909 0.72870524 0.202964164 0.202893823 0.465057285 0.110032491 6.49E-10 9.187769091 3.700707873 SQS(ph)LPGADSLLAKPIDK ddPTM_HeLa_Curcumin_4h_R1 2 SQSLPGADSLLAKPIDK 17 1 H0Y4W2;F2Z2U4;Q9Y4A5-2;Q9Y4A5 H0Y4W2 TRRAP Transformation/transcription domain-associated protein 1 0 S(0.029)QS(0.666)LPGADS(0.305)LLAKPIDK;S(0.052)QS(0.943)LPGADS(0.005)LLAKPIDK ; 100.47 0.00091535 57440000 2992 2288.1 3735.4 3986.3 3418.5 3158.9 6128 32034 0 3436.4 TRUE FALSE FALSE 2755.180043 2485.873168 3873.83721 3969.805747 3377.73662 2503.708532 6299.935187 41801.01913 0 3555.814644 0.774837926 0.699100886 1.089437329 1.116426514 0.949919205 0.704116717 1.771727668 11.75568001 0 1 11.79596441 -4.259892205 4.095916568 0.907621981 12.6925309 0.990538782 0.319374564 0.007511524 0.270473712 0.022610666 0.260748379 5.50E-05 4.259892205 11.78490892 up GGDPLEKQDQISGLS(ph)QSEVK ddPTM_HeLa_Curcumin_4h_R1 2 GGDPLEKQDQISGLSQSEVK 20 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 0 GGDPLEKQDQIS(0.206)GLS(0.588)QS(0.206)EVK;GGDPLEKQDQIS(0.003)GLS(0.966)QS(0.031)EVK ; 126.04 3.38E-05 5475200 1596.38 1414.39 1513.15 1775.84 1627.65 1951.85 1789.22 3516.2 1898.9 1654.91 TRUE FALSE FALSE 1470.024839 1536.643569 1569.22867 1768.492045 1608.241337 1547.014308 1839.420698 4588.273193 1690.595421 1712.417999 0.85844977 0.897353082 0.916381789 1.032745536 0.939163999 0.903409278 1.074165711 2.679411917 0.987256278 1 10.74181919 -4.259846503 4.091022327 0.935028213 2.830574064 0.990663028 0.050318741 0.017809069 0.638496465 0.008601211 0.099353893 5.50E-05 4.259846503 1.895545851 up IISIFSGTEK ddPTM_HeLa_Curcumin_4h_R1 1 IISIFSGTEK 10 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 0 0 137.95 0.00036914 405510 303.83 221.72 269.46 348.16 333.05 338.19 307.71 262.51 301.52 476.12 FALSE FALSE TRUE 279.7815349 240.8844888 279.4464246 346.7194062 329.0785963 268.0455818 316.3435144 342.5480906 268.4440104 492.6651346 0.567893921 0.48894162 0.567213722 0.703762824 0.667955926 0.544072562 0.642106559 0.695295986 0.544881283 1 8.944463567 -9.197308173 0.884821112 1.006068421 0.607688781 0 0.153595433 0.203759891 0.280729275 0.053280628 0.014174544 6.35E-10 9.197308173 -0.39837964 KAEEK(ac)LESYR ddPTM_HeLa_Curcumin_4h_R1 2 KAEEKLESYR 10 2 A0A6I8PRS5;Q8N954-2;Q8N954 A0A6I8PRS5 GPATCH11 G patch domain-containing protein 11 0 1 ; KAEEK(1)LESYR;KAEEK(1)LESYR 89.356 0.0052562 17209400 7286.1 5606.4 7277.5 7201.1 6406.1 9681.6 10525.9 15099.2 7773 6727.3 FALSE TRUE FALSE 6709.397497 6090.992234 7547.210552 7171.303756 6329.711441 7673.527026 10821.22842 19702.87657 6920.321347 6961.073174 0.963845276 0.875007643 1.084202157 1.030200887 0.909301092 1.102348278 1.554534503 2.830436641 0.994145755 1 12.76509403 -4.198942693 1.649396522 0.980494882 3.702160509 0.989062883 0.058716538 0.077881391 0.178239855 0.008354452 0.352244474 6.32E-05 4.198942693 2.721665626 up IISNASCTTNCLAPLAK ddPTM_HeLa_Curcumin_4h_R1 3 IISNASCTTNCLAPLAK 17 0 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 ;; ;; 334.6 1.29E-178 171868300 2799.72 2425.28 2419.07 2346.89 2638.14 4138.9 3094.78 2803.93 2923.81 2721.24 FALSE FALSE TRUE 2578.119208 2634.910396 2508.722862 2337.179191 2606.681904 3280.445485 3181.611198 3658.835349 2603.075358 2815.802887 0.915589376 0.935758113 0.890944062 0.830022301 0.925733088 1.165012473 1.129912613 1.29939328 0.924452265 1 11.45933063 -5.20537207 4.221246585 0.939873826 1.19893088 0.825293547 0.058662469 0.082499297 3.062588626 0.009523296 0.025159191 6.23E-06 5.20537207 0.259057054 IISPGSSTPS(ph)STRSPPPGR ddPTM_HeLa_Curcumin_4h_R1 1 IISPGSSTPSSTRSPPPGR 19 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 IISPGSST(0.001)PS(0.325)S(0.325)T(0.325)RS(0.024)PPPGR 79.326 0.002043 14548000 1210.3 1078.5 927.79 1071.4 802.8 1204.4 1060.1 982.87 842.28 1063.4 TRUE FALSE FALSE 1114.503478 1171.720734 962.1747136 1066.966831 793.2271343 954.5938636 1089.843553 1282.542538 749.8839913 1100.353071 1.012859879 1.064858876 0.874423618 0.969658611 0.720884192 0.867534148 0.990448958 1.165573644 0.681493978 1 10.1037508 -6.759341775 24.99933935 1.01065136 0.923367976 0 0.14940559 89.25873143 1063780.437 0.017234056 0.023690703 1.74E-07 6.759341775 -0.087283385 IISPGSSTPSSTRS(ph)PPPGR ddPTM_HeLa_Curcumin_4h_R1 2 IISPGSSTPSSTRSPPPGR 19 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 IISPGSST(0.001)PS(0.131)S(0.131)T(0.099)RS(0.638)PPPGR;IISPGSSTPS(0.005)S(0.008)T(0.008)RS(0.98)PPPGR ; 89.816 0.00089358 15913300 3956.2 3380.8 3562.6 3108 4110.6 3829.6 3447.5 3372.6 3448.9 3348.6 TRUE FALSE FALSE 3643.062595 3673.021287 3694.63309 3095.13992 4061.58378 3035.297792 3544.227572 4400.890214 3070.564299 3464.963601 1.051399961 1.060046139 1.066283377 0.893267658 1.172186565 0.875997021 1.022875845 1.270111528 0.886175052 1 11.75862448 -4.261779315 9.268857831 1.021050585 1.271042935 0.423677984 0.091287546 0.048043515 95.38312242 0.009852293 0.076246529 5.47E-05 4.261779315 0.249992349 IISSIEQK ddPTM_HeLa_Curcumin_4h_R1 2 IISSIEQK 8 0 P62258;P62258-2;B4DJF2;I3L3T1;K7EIT4 P62258 YWHAE 14-3-3 protein epsilon 0 0 ; ; 139.97 0.0006971 11153300 9846.2 8313.2 9309.4 9180 11085.8 8819.9 8349.5 9009 7803.8 7842.6 FALSE FALSE TRUE 9066.86288 9031.755965 9654.414553 9142.015592 10953.60908 6990.553319 8583.764498 11755.80263 6947.742664 8115.129766 1.117278853 1.112952747 1.189680859 1.126539668 1.349776207 0.861422247 1.057748273 1.448627806 0.856146835 1 12.98639845 -13.52287874 0.126298012 0.460954714 1.223816903 0.251761258 0.154705309 124.1221127 1.119433802 16.73712488 0.582960101 3.00E-14 13.52287874 0.76286219 IISVT(ph)PVKNIDPVK ddPTM_HeLa_Curcumin_4h_R1 1 IISVTPVKNIDPVK 14 1 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 1 0 IIS(0.004)VT(0.996)PVKNIDPVK 161.49 0.0025974 38255000 5581.9 4426.9 5366.2 5267.3 4903.7 7090.4 5586.9 2547.4 5977.9 5731 TRUE FALSE FALSE 5140.086725 4809.54151 5565.076093 5245.505308 4845.22658 5619.771115 5743.653378 3324.090533 5322.139326 5930.151823 0.866771523 0.811031767 0.938437372 0.884548232 0.817049331 0.94766058 0.968550814 0.560540545 0.897471007 1 12.53385333 -13.51211563 0.021959622 2.119010343 4.21E-07 0.176215369 0.107523482 2341.03817 4.150250631 272.2435666 146.5219594 3.08E-14 13.51211563 -2.119009922 IISVTPVK(ac)NIDPVK ddPTM_HeLa_Curcumin_4h_R1 1 IISVTPVKNIDPVK 14 1 Q29RF7 Q29RF7 PDS5A Sister chromatid cohesion protein PDS5 homolog A 0 1 IISVTPVK(1)NIDPVK 136.01 0.0013362 613820 196.09 338.79 153.49 149.75 224.35 356.68 187.13 210.13 132.08 197.17 FALSE TRUE FALSE 180.5692696 368.073498 159.1784744 149.1303742 221.6747728 282.7005474 192.3803642 274.1976697 117.5911544 204.0216428 0.885049581 1.804090453 0.780203866 0.730953697 1.086525771 1.385639991 0.942940962 1.34396364 0.57636608 1 7.672578393 -1.000000003 0.266080586 0.964245866 2.959237245 0.096227526 0.330555251 103.2262883 1.305833171 0.146089742 95.32022711 0.099999999 1.000000003 1.994991379 IITEGFEAAK ddPTM_HeLa_Curcumin_4h_R1 1 IITEGFEAAK 10 0 P40227;P40227-2 P40227 CCT6A T-complex protein 1 subunit zeta 0 0 118.18 3.71E-07 0 516.48 284.31 482.71 451.36 379.8 594.57 517.02 586.26 386.82 526.35 FALSE FALSE TRUE 475.600063 308.8844895 500.5996572 449.4923919 375.2711331 471.2494798 531.5261897 765.0079752 344.3868138 544.6406233 0.873236484 0.567134504 0.919137567 0.825300891 0.689025234 0.865248495 0.975920941 1.404610568 0.632319366 1 9.089160783 -4.266678912 2.893208873 0.881071084 1.492503649 0.566091385 0.147157381 0.232922761 2.756191593 0.019777569 0.329698233 5.41E-05 4.266678912 0.611432566 IIVEK(ac)PFGR ddPTM_HeLa_Curcumin_4h_R1 2 IIVEKPFGR 9 1 P11413;P11413-3;P11413-2;E9PD92;E7EM57;E7EUI8 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 1 ; IIVEK(1)PFGR;IIVEK(1)PFGR 131.22 0.00054234 20883900 3892 4330.8 3969.5 3373.8 7114.4 7690.4 5925.5 5717.8 7916.9 3626.2 FALSE TRUE FALSE 3583.944093 4705.135054 4116.613162 3359.84011 7029.565427 6095.324351 6091.753582 7461.130898 7048.435877 3752.21018 0.955155474 1.253963618 1.09711689 0.895429613 1.873446606 1.624462399 1.623510755 1.988462943 1.878475762 1 11.87352493 -5.761783624 25 1.005904338 1.755544454 0.414907184 0.308028686 2.202117905 159943.1145 0.019910301 0.037785625 1.73E-06 5.761783624 0.749640116 IIVEKPFGR ddPTM_HeLa_Curcumin_4h_R1 2 IIVEKPFGR 9 1 P11413;P11413-3;P11413-2;E9PD92;E7EM57;E7EUI8 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 0 ; ; 95.815 0.0068289 23896000 12893 7161.1 10982.7 8082.9 7541.4 8559 6558.6 6271.4 7342.7 7500.8 FALSE FALSE TRUE 11872.50545 7780.073575 11389.72852 8049.455101 7451.47373 6783.76692 6742.616664 8183.52099 6537.224181 7761.452242 1.529675771 1.002399207 1.467473891 1.037106826 0.96006179 0.874033198 0.868731322 1.054380126 0.842268171 1 12.9221109 -6.043150832 6.804671277 1.249295555 0.937278586 0.161738293 0.209289622 0.204618921 25.89207291 0.032579176 0.054920341 9.05E-07 6.043150832 -0.312016969 IIYDS(ph)DS(ph)ESEETLQVK ddPTM_HeLa_Curcumin_4h_R1 1 IIYDSDSESEETLQVK 16 0 P35251-2;P35251;E0CX09;D6RAD2 P35251-2 RFC1 Replication factor C subunit 1 2 0 IIY(0.21)DS(0.801)DS(0.852)ES(0.136)EETLQVK 86.573 0.01741 3271600 1569 1202 1289.5 2245.5 1391.9 2470.5 1611.9 1216.2 1716.2 1505.5 TRUE FALSE FALSE 1444.811994 1305.895524 1337.290004 2236.208716 1375.302502 1958.090452 1657.125576 1587.013781 1527.937154 1557.816013 0.927459971 0.838286109 0.85843899 1.435476781 0.882840137 1.256945901 1.063749225 1.018742758 0.980820033 1 10.60530914 IIYDS(ph)DSESEETLQVK ddPTM_HeLa_Curcumin_4h_R1 1 IIYDSDSESEETLQVK 16 0 P35251-2;P35251;E0CX09;D6RAD2 P35251-2 RFC1 Replication factor C subunit 1 1 0 IIYDS(0.844)DS(0.155)ES(0.002)EETLQVK 207.21 1.47E-32 0 2137.6 1057.3 1782.7 1945.3 1712.6 2113.1 1718.5 791.76 1973 1588.3 TRUE FALSE FALSE 1968.406704 1148.688301 1848.76843 1937.250864 1692.178364 1674.81924 1766.716485 1033.163979 1756.566836 1643.493307 1.197696818 0.698930927 1.124901709 1.178739734 1.029622911 1.019060579 1.07497638 0.628638994 1.068800724 1 10.68254987 -4.260750682 24.47894549 1.066474927 0.628638823 0.460026837 0.132826069 28.80484259 1023536.655 0.018833591 0.150965893 5.49E-05 4.260750682 -0.437836104 IIYIVHDEVKDK ddPTM_HeLa_Curcumin_4h_R1 1 IIYIVHDEVKDK 12 1 P25788-2;P25788;G3V4X5 P25788-2 PSMA3 Proteasome subunit alpha type-3 0 0 68.626 0.017975 13417000 8040.1 6620.5 7760.2 6207.8 7171.9 11442 9001.4 9416.8 7700 7029.9 FALSE FALSE TRUE 7403.717601 7192.74652 8047.799839 6182.113768 7086.379777 9068.800222 9253.955058 12287.93897 6855.329264 7274.188502 1.017806673 0.988803977 1.106350191 0.849869888 0.974181488 1.246709543 1.272163219 1.689252206 0.942418424 1 12.8285706 -4.172758624 1.046415447 1.001482975 2.114349091 0.881122903 0.079375854 0.470392082 0.356532866 0.011236739 0.606998092 6.72E-05 4.172758624 1.112866116 IK(ac)IIAPPERK ddPTM_HeLa_Curcumin_4h_R1 2 IKIIAPPERK 10 2 P60709;P63267-2;Q562R1;A0A2R8YFE2;P63261;P68133;P68032;P63267;P62736;A6NL76 P60709;P63261;P68133 ACTB;ACTG2;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 0 1 ; IK(1)IIAPPERK;IK(1)IIAPPERK 110.38 5.04E-05 0 5510.8 4677.1 5132.7 4751.9 4564 5326.6 5185.8 5859 6202.5 5132.5 FALSE TRUE FALSE 5074.614365 5081.367683 5322.922377 4732.237897 4509.577281 4221.803117 5331.299591 7645.382128 5522.101268 5310.853993 0.955517582 0.956789189 1.0022724 0.891050272 0.849124696 0.794938653 1.003849776 1.439576787 1.039776517 1 12.37472815 -4.271756198 4.444248106 0.951718132 1.469123415 0.811583845 0.071970342 0.062090226 3.009203346 0.010372062 0.098812675 5.35E-05 4.271756198 0.517405283 IKADQCHT(ph)MR ddPTM_HeLa_Curcumin_4h_R1 1 IKADQCHTMR 10 1 Q6P2S7-2;Q6P2S7 Q6P2S7-2 GNN Tetratricopeptide repeat protein GNN 1 0 IKADQCHT(1)MR 101.6 0.017375 8742000 1495 1506 1758.7 1528.8 1710.9 2748.9 1799.2 1993.9 1421.7 1556.8 TRUE FALSE FALSE 1376.669172 1636.171929 1823.878969 1522.474231 1690.498635 2178.747154 1849.68071 2601.830931 1265.743067 1610.898684 0.854596994 1.01568891 1.132212092 0.945108619 1.049413381 1.352504149 1.148229077 1.615142502 0.785737228 1 10.65365004 -1 0.417396895 0.935504542 12.61390188 0.757773453 0.113743267 22.96997367 0.263764083 0.024875377 225.8317861 0.1 1 11.67839734 IKDNGDLVLS(ph)SPSNVTLPQVK ddPTM_HeLa_Curcumin_4h_R1 1 IKDNGDLVLSSPSNVTLPQVK 21 1 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;P04150-9;P04150-8;P04150-13;P04150-12;P04150-11 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 0 IKDNGDLVLS(0.422)S(0.155)PS(0.302)NVT(0.12)LPQVK 94.955 0.0001418 62881000 6500.2 4803.3 5514.3 5788.9 5083.2 8927.2 8373.9 6367.7 6255.5 4743 TRUE FALSE FALSE 5985.702311 5218.475849 5718.664809 5764.947066 5022.58616 7075.59809 8608.849097 8309.182417 5569.2873 4907.818897 1.219625752 1.063298373 1.165215125 1.174645436 1.023384576 1.441699101 1.754108959 1.693049925 1.134778487 1 12.2608663 -5.017784301 3.059837494 1.108674594 1.721562204 0.926973968 0.069427432 0.057214182 1.082701807 0.012977428 0.041926881 9.60E-06 5.017784301 0.61288761 IKDNGDLVLSS(ph)PSNVTLPQVK ddPTM_HeLa_Curcumin_4h_R1 1 IKDNGDLVLSSPSNVTLPQVK 21 1 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;P04150-9;P04150-8;P04150-13;P04150-12;P04150-11 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 0 IKDNGDLVLS(0.281)S(0.47)PS(0.248)NVT(0.001)LPQVK 91.067 0.00019436 55129000 3792.2 3436.3 3618.1 3465.7 3282.6 5651 5356.5 4177.3 3858 3301.7 TRUE FALSE FALSE 3492.043368 3733.31846 3752.189969 3451.359852 3243.457139 4478.9189 5506.788974 5450.93954 3434.787052 3416.433829 1.022131129 1.092753042 1.098276787 1.010222947 0.949369226 1.310992434 1.611852958 1.595505668 1.005372041 1 11.73827547 -4.983222398 2.841428702 1.020503561 1.60747894 0.962342442 0.045895359 0.034492046 0.559456204 0.007045923 0.024265701 1.04E-05 4.983222398 0.586975379 IKDPDASKPEDWDER ddPTM_HeLa_Curcumin_4h_R1 2 IKDPDASKPEDWDER 15 2 P27797;K7EJB9 P27797 CALR Calreticulin 0 0 ; ; 122.1 0.0028583 61273000 7574.6 5819.1 6735.5 6982.4 7537.2 9060.2 6610.9 6129.4 6875.4 6251.8 FALSE FALSE TRUE 6975.062417 6322.077075 6985.123555 6953.508679 7447.323813 7181.012391 6796.384062 7998.225844 6121.185821 6469.049585 1.078220583 0.977280664 1.079775856 1.074888759 1.151223795 1.110056786 1.050600088 1.23638345 0.94622645 1 12.65933806 -1 0.178028487 1.004814353 1.696624752 0.552501836 0.054041844 36.90160572 0.398168971 0.064515666 6.925986924 0.1 1 0.691810399 IKEDEDDKTVLDLAVVLFETATLR ddPTM_HeLa_Curcumin_4h_R1 1 IKEDEDDKTVLDLAVVLFETATLR 24 2 P14625;H0YIV0 P14625 HSP90B1 Endoplasmin 0 0 104.81 1.67E-06 1427500 939.81 1241.3 756.05 1117.2 923.25 1462 883.63 1073.7 1101.1 1119.1 FALSE FALSE TRUE 865.4230468 1348.592441 784.0698781 1112.577322 912.2408467 1158.76472 908.4222796 1401.066187 980.3120848 1157.988642 0.747350203 1.164599023 0.677096346 0.960784314 0.787780479 1.000670195 0.784482893 1.209913584 0.846564508 1 10.17740539 -4.249872568 24.40692937 0.886157897 1.209913853 0.328392115 0.139186758 1161.844908 2451525.549 0.018836824 0.393838416 5.63E-05 4.249872568 0.323755957 IKEEPVS(ph)EEGEEDEEQEAEEEPMDTSPSGLHSK ddPTM_HeLa_Curcumin_4h_R1 1 IKEEPVSEEGEEDEEQEAEEEPMDTSPSGLHSK 33 1 A0A0C4DH01;Q9NVU0-3;Q9NVU0-2;Q9NVU0-5;Q9NVU0-4;Q9NVU0 A0A0C4DH01 POLR3E DNA-directed RNA polymerase III subunit RPC5 1 0 IKEEPVS(0.951)EEGEEDEEQEAEEEPMDT(0.037)S(0.01)PS(0.002)GLHS(0.001)K 40.43 0.012837 17729000 1595.2 1219.7 1114.4 1116.7 2724.1 3547.8 1776.1 1234.6 2077.3 1603.2 TRUE FALSE FALSE 1468.938237 1325.125433 1155.700644 1112.079391 2691.616887 2811.946288 1825.932586 1611.023857 1849.425387 1658.911081 0.885483408 0.798792321 0.696662201 0.670367089 1.622520289 1.695055462 1.100681409 0.971133339 1.114842989 1 10.69602084 -5.764765139 24.99981588 0.894408766 1.354564883 0.501455873 0.236108512 59.31744393 445895.2952 0.035768516 0.066809353 1.72E-06 5.764765139 0.460156117 IKEEVLS(ph)ESEAENQQAGAAALAPEIVIK ddPTM_HeLa_Curcumin_4h_R1 4 IKEEVLSESEAENQQAGAAALAPEIVIK 28 1 Q9UJX5;Q9UJX5-3 Q9UJX5 ANAPC4 Anaphase-promoting complex subunit 4 1 0 IKEEVLS(0.848)ES(0.152)EAENQQAGAAALAPEIVIK;IKEEVLS(0.915)ES(0.085)EAENQQAGAAALAPEIVIK;IKEEVLS(0.802)ES(0.198)EAENQQAGAAALAPEIVIK;IKEEVLS(0.726)ES(0.274)EAENQQAGAAALAPEIVIK ;;; 86.195 2.35E-06 390273000 8903.4 7078.9 7547.1 7463.2 7496.6 8952.4 7506.9 6093.79 8547.5 7429.2 TRUE FALSE FALSE 8198.686495 7690.768573 7826.802165 7432.319256 7407.207941 7095.571326 7717.52341 7951.758519 7609.860635 7687.364147 1.066514652 1.00044286 1.018138599 0.966822842 0.963556272 0.92301746 1.003923226 1.034393372 0.989918064 1 12.90827329 -6.520875911 2.099053418 1.030431185 0.976148281 0.154673354 0.034765395 0.301506272 2.659268756 0.006196139 0.009694757 3.01E-07 6.520875911 -0.054282904 IKGEHPGLSIGDVAK ddPTM_HeLa_Curcumin_4h_R1 2 IKGEHPGLSIGDVAK 15 1 Q5T7C4;P09429;B2RPK0 Q5T7C4 HMGB1;HMGB1P1 High mobility group protein B1;Putative high mobility group protein B1-like 1 0 0 ; ; 68.262 0.0074055 21049700 26075 21337.6 20896 21285.4 24817 31807 25169 21550.2 26462 22318 FALSE FALSE TRUE 24011.13624 23181.92707 21670.42414 21197.32665 24521.07348 25209.86966 25875.1744 28120.75678 23559.1848 23093.54884 1.039733495 1.003826966 0.93837566 0.917889528 1.061814867 1.091641213 1.120450329 1.217688843 1.020163032 1 14.49520227 -4.725903739 1.247256254 1.006104105 1.223821189 0.749789291 0.041765465 0.323327365 0.70497032 0.007071115 0.072692789 1.88E-05 4.725903739 0.217717084 IKGS(ph)SPGIQDTLEAEDGAFETDEAPEDR ddPTM_HeLa_Curcumin_4h_R1 3 IKGSSPGIQDTLEAEDGAFETDEAPEDR 28 1 Q9UNX4 Q9UNX4 WDR3 WD repeat-containing protein 3 1 0 IKGS(0.493)S(0.493)PGIQDT(0.014)LEAEDGAFETDEAPEDR;IKGS(0.374)S(0.374)PGIQDT(0.252)LEAEDGAFETDEAPEDR;IKGS(0.48)S(0.48)PGIQDT(0.04)LEAEDGAFETDEAPEDR ;; 126.59 1.21E-10 162094000 7494.2 5750.1 6869.6 8162.9 6361.5 9148.1 6242.9 4765 8608.8 7047.7 TRUE FALSE FALSE 6901.026162 6247.113022 7124.193419 8129.124083 6285.643267 7250.68094 6418.058972 6217.826565 7664.436178 7292.60705 0.946304403 0.856636451 0.976906252 1.114707542 0.861919918 0.994250875 0.880077444 0.85262054 1.050987133 1 12.83221894 -4.664010494 5.00715208 0.968824118 0.859626047 0.257195963 0.07376395 0.199855526 8.011646177 0.00933023 0.037011488 2.17E-05 4.664010494 -0.109198071 IKNENTEGS(ph)PQEDGVELEGLK ddPTM_HeLa_Curcumin_4h_R1 5 IKNENTEGSPQEDGVELEGLK 21 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 IKNENTEGS(1)PQEDGVELEGLK;IKNENT(0.149)EGS(0.851)PQEDGVELEGLK;IKNENTEGS(1)PQEDGVELEGLK;IKNENT(0.001)EGS(0.999)PQEDGVELEGLK;IKNENT(0.004)EGS(0.996)PQEDGVELEGLK ;;;; 135.43 1.56E-05 769257300 15315.7 8746.2 13901.6 16870.2 15429.9 18974.9 16031.1 11175.1 15399.7 13543.9 TRUE FALSE FALSE 14103.44618 9502.182556 14416.80553 16800.39558 15245.90852 15039.29185 16480.88952 14582.33655 13710.39144 14014.54952 1.00634317 0.67802269 1.028702743 1.19878242 1.087862903 1.073119891 1.175984251 1.040514112 0.978296978 1 13.77463775 -6.515422902 24.99762446 0.972737404 1.114662159 0.412467694 0.103700906 341.2201685 1144029.038 0.016543597 0.02398553 3.05E-07 6.515422902 0.141924755 IKPNLSSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 IKPNLSSSPR 10 1 A0A1P0AZG4;Q96JN0-3 A0A1P0AZG4 1 0 IKPNLSS(0.04)S(0.959)PR;IKPNLS(0.001)S(0.138)S(0.861)PR ; 75.652 0.016251 87462000 9453.5 6804.3 8498.5 10008.1 8793.7 9719.8 7066.7 4013.6 10723.5 8861.9 TRUE FALSE FALSE 8705.2455 7392.433373 8813.461886 9966.689134 8688.840871 7703.803915 7264.972583 5237.328164 9547.158879 9169.850365 0.94933343 0.806167285 0.961134755 1.086897685 0.947544455 0.840123187 0.792267299 0.571146524 1.041146638 1 13.16268248 -4.276872558 1.073764083 0.968152759 0.385847842 0.747888982 0.071964993 0.637850185 0.586177768 0.010884261 0.419152055 5.29E-05 4.276872558 -0.582304917 IKPVTENLVLSSHTGFCQS(ph)S(ph)GDEALSK ddPTM_HeLa_Curcumin_4h_R1 1 IKPVTENLVLSSHTGFCQSSGDEALSK 27 1 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6;A0A096LP59 P46100-5 ATRX Transcriptional regulator ATRX 2 0 IKPVTENLVLS(0.329)S(0.329)HT(0.503)GFCQS(0.349)S(0.349)GDEALS(0.142)K 47.96 0.0085738 0 1090.1 1286.4 807.05 1162.7 1312.8 1355.9 515.73 372.06 1221.9 922.38 TRUE FALSE FALSE 1003.817435 1397.590684 836.959983 1157.889055 1297.145717 1074.671056 530.1999958 485.4993812 1087.860627 954.4326363 1.051742571 1.464315689 0.876918864 1.213170015 1.359075191 1.125978948 0.555513271 0.50867852 1.139798227 1 9.898499566 -4.756891331 20.92336506 1.088629053 0.532093192 0.669200841 0.169982056 6.919962794 31823.67334 0.024289369 0.084414279 1.75E-05 4.756891331 -0.556535862 IKQHLENDPGS(ph)NEDTDIPK ddPTM_HeLa_Curcumin_4h_R1 1 IKQHLENDPGSNEDTDIPK 19 1 K7EML9;K7ER96;O43396 K7EML9 TXNL1 Thioredoxin-like protein 1 1 0 IKQHLENDPGS(0.908)NEDT(0.092)DIPK 63.436 0.008207 0 1957 1998.7 2338.3 2269.1 2265.3 2899.4 2077.6 1824.1 2756.9 2389.7 TRUE FALSE FALSE 1802.101385 2171.458722 2424.959455 2259.711065 2238.287777 2298.031757 2135.891864 2380.259693 2454.474967 2472.741897 0.728786691 0.87815826 0.980676333 0.913848335 0.905184556 0.929345582 0.86377469 0.96259933 0.992612682 1 11.27189594 -6.972456952 23.70378712 0.868324161 0.922386456 0 0.078181985 299.9355543 258125.5354 0.01676457 0.022032586 1.07E-07 6.972456952 0.054062295 IKTELNS(ph)SAESEQPLDK ddPTM_HeLa_Curcumin_4h_R1 2 IKTELNSSAESEQPLDK 17 1 Q9Y5B6-3;Q9Y5B6-4;Q9Y5B6-2;Q9Y5B6 Q9Y5B6-3 PAXBP1 PAX3- and PAX7-binding protein 1 1 0 IKT(0.006)ELNS(0.441)S(0.297)AES(0.255)EQPLDK;IKT(0.002)ELNS(0.838)S(0.151)AES(0.01)EQPLDK ; 69.272 0.0089132 19076600 4989.4 4836.8 4568 4825.2 4731 5955.6 4843.1 3442 5620.1 5055.9 TRUE FALSE FALSE 4594.483725 5254.87144 4737.294098 4805.234601 4674.585915 4720.341427 4978.984351 4491.449955 5003.589091 5231.592149 0.878219019 1.004449753 0.905516708 0.91850329 0.893530264 0.902276266 0.951714929 0.858524485 0.956418037 1 12.35303436 -9.49080435 1.121185724 1.002126483 0.912994083 0.266458625 0.040297208 0.402877236 0.87018926 0.029209166 0.006445805 3.23E-10 9.49080435 -0.0891324 IKTEPSS(ph)PLSDPSDIIR ddPTM_HeLa_Curcumin_4h_R1 2 IKTEPSSPLSDPSDIIR 17 1 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 0 IKT(0.002)EPS(0.078)S(0.873)PLS(0.042)DPS(0.004)DIIR;IKT(0.011)EPS(0.072)S(0.797)PLS(0.111)DPS(0.008)DIIR ; 61.127 0.014387 60541000 4039.3 2794.7 3325.9 4043.8 2834.2 3518.4 3338.9 2765.2 4179.1 3466.3 TRUE FALSE FALSE 3719.585143 3036.261415 3449.16078 4027.067827 2800.404016 2788.644179 3432.580548 3608.296751 3720.663186 3586.753667 1.0370339 0.846520753 0.961638601 1.122761193 0.78076285 0.777484165 0.957015972 1.00600629 1.037334462 1 11.80846295 -6.716197607 0.772887492 1.016131744 0.904516813 0.124464483 0.102462573 0.861223288 1.03647762 0.023189848 0.039487329 1.92E-07 6.716197607 -0.111614931 IKTEPSSPLS(ph)DPSDIIR ddPTM_HeLa_Curcumin_4h_R1 1 IKTEPSSPLSDPSDIIR 17 1 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 0 IKTEPS(0.01)S(0.329)PLS(0.433)DPS(0.229)DIIR 98.76 0.0010561 31325000 2932.8 2073.5 2328.6 2577 2384.3 3024.4 2453.9 1831.7 3682.4 2597.9 TRUE FALSE FALSE 2700.665785 2252.724101 2414.899964 2566.337057 2355.86878 2397.105348 2522.74983 2390.176898 3278.449933 2688.176832 1.004645882 0.838011873 0.898341186 0.954675685 0.876381625 0.891721601 0.938461265 0.889144222 1.219581203 1 11.39241233 -7.285536864 24.67380584 1.002193896 0.900761298 0.468554985 0.075066973 240.9840558 246746.7974 0.004961334 0.005675122 5.18E-08 7.285536864 -0.101432598 IKVDFVIPK ddPTM_HeLa_Curcumin_4h_R1 1 IKVDFVIPK 9 1 O75534-2;O75534;O75534-3;O75534-4;E9PLT0 O75534-2 CSDE1 Cold shock domain-containing protein E1 0 0 80.688 0.010177 0 3329.5 2602.7 2590.3 2555.7 2512.3 3493.9 2557.4 2369.5 2830.9 2667.8 FALSE FALSE TRUE 3065.966562 2827.665791 2686.298797 2545.125191 2482.342463 2769.225756 2629.153761 3091.949642 2520.357353 2760.505851 1.11065389 1.024328852 0.973118313 0.921977829 0.899234632 1.003158807 0.952417384 1.120066324 0.913005619 1 11.43071694 -6.878873174 4.107295706 1.052862705 0.972171865 0 0.075408934 0.246215334 7.604322248 0.011021186 0.0146949 1.32E-07 6.878873174 -0.08069084 IKWDEQTSNTKGDDDEES(ph)DEEAVK ddPTM_HeLa_Curcumin_4h_R1 1 IKWDEQTSNTKGDDDEESDEEAVK 24 2 O43395 O43395 PRPF3 U4/U6 small nuclear ribonucleoprotein Prp3 1 0 IKWDEQTS(0.001)NTKGDDDEES(0.999)DEEAVK 54.363 0.0029658 30572000 3195.8 2641.3 3159.4 2935.6 2636.9 3135.3 2975.9 2649.7 3416.4 2889.4 TRUE FALSE FALSE 2942.849058 2869.602203 3276.490143 2923.453265 2605.45669 2485.003438 3059.395745 3457.581332 3041.629467 2989.806435 0.984294175 0.959795313 1.095887046 0.977806868 0.871446612 0.831158636 1.023275523 1.156456583 1.01733324 1 11.54583637 -6.001809764 24.99914738 0.998213728 0.959418738 0.031430796 0.088696055 222.1866441 3069255.952 0.013292177 0.023836399 9.96E-07 6.001809764 -0.038794989 IKWDEQTSNTKGDDDEES(ph)DEEAVKK ddPTM_HeLa_Curcumin_4h_R1 1 IKWDEQTSNTKGDDDEESDEEAVKK 25 3 O43395 O43395 PRPF3 U4/U6 small nuclear ribonucleoprotein Prp3 1 0 IKWDEQT(0.018)S(0.036)NT(0.022)KGDDDEES(0.924)DEEAVKK 54.934 0.0039542 155460000 4943.6 3569.9 4153.1 4498.7 4236.8 4930.1 4162.3 3724.3 5237.3 4540.3 TRUE FALSE FALSE 4552.308844 3878.466249 4307.017539 4480.085571 4186.278927 3907.541686 4279.082936 4859.821925 4662.781293 4698.075087 0.968973198 0.825543691 0.916762176 0.953600249 0.891062584 0.831732489 0.910816208 1.034428321 0.992487605 1 12.19785406 -7.483790255 14.10292021 0.986319415 0.906794625 0.29410156 0.055951233 2.716594439 980.0150804 0.009548994 0.010711397 3.28E-08 7.483790255 -0.07952479 ILAT(ph)PPQEDAPSVDIANIR ddPTM_HeLa_Curcumin_4h_R1 2 ILATPPQEDAPSVDIANIR 19 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 1 0 ILAT(1)PPQEDAPSVDIANIR;ILAT(0.999)PPQEDAPS(0.001)VDIANIR ; 218.83 5.30E-18 62929000 6398.7 3958.4 5323 4933.5 5873.9 8293.5 5695.9 7805.9 5770.7 5090.7 TRUE FALSE FALSE 5892.236143 4300.546458 5520.275063 4913.086484 5803.857579 6573.334613 5855.711624 10185.88298 5137.668648 5267.601446 1.118580478 0.816414549 1.047967489 0.932698978 1.101802716 1.247880023 1.111646673 1.933685204 0.975333594 1 12.36293048 -1.903424702 1.119419941 1.03562291 200 0.858799328 0.109286968 91.74980733 0.660985973 0.016036391 46241.95145 0.01249037 1.903424702 198.9643771 ILATPPQEDAPSVDIANIR ddPTM_HeLa_Curcumin_4h_R1 1 ILATPPQEDAPSVDIANIR 19 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 0 0 141.54 0.0016285 2044800 1075 740.88 756.59 782.38 689.9 1039.1 723.04 777.44 992.37 744.46 FALSE FALSE TRUE 989.9126157 804.9183659 784.629891 779.1427189 681.6733931 823.5789469 743.3265564 1014.477877 883.5094938 770.3299296 1.285050181 1.044900808 1.018563424 1.011440279 0.884910954 1.069124949 0.964945704 1.316939454 1.146923493 1 9.589332669 -7.035838542 24.67631562 1.136205376 1.032985798 0.117006361 0.122468406 888.7908952 611967.9228 0.023622123 0.028937387 9.21E-08 7.035838542 -0.103219578 ILDDICVAK ddPTM_HeLa_Curcumin_4h_R1 2 ILDDICVAK 9 0 Q15046;Q15046-2 Q15046 KARS Lysine--tRNA ligase 0 0 ; ; 140.5 1.64E-05 1798720 2111.22 1694.4 1859.17 1935.46 1865.74 2285.59 1767.77 1581.45 2119.79 1960.74 FALSE FALSE TRUE 1944.114709 1840.856386 1928.072476 1927.451579 1843.492269 1811.53287 1817.368868 2063.626825 1887.25434 2028.875569 0.958222741 0.907328381 0.950315783 0.950009754 0.908627566 0.892875294 0.895751763 1.017128333 0.930197184 1 10.98646467 -8.101014263 0.65514983 0.996897613 0.927381729 0 0.040857154 0.501144903 0.480508744 0.014739792 0.009196891 7.92E-09 8.101014263 -0.069515884 ILDEIEEHNIK ddPTM_HeLa_Curcumin_4h_R1 3 ILDEIEEHNIK 11 0 B5MCX3;Q15019;Q15019-3;Q15019-2;H7C2Y0;C9J2Q4 B5MCX3 2-Sep Septin-2 0 0 ;; ;; 163.46 0.00022952 22942200 8806 7154.2 7436.9 8202.1 8352.1 10911.1 7896.3 7718.7 9476.1 8129.4 FALSE FALSE TRUE 8108.995808 7772.57717 7712.518056 8168.161883 8252.506662 8648.014867 8117.848926 10072.0961 8436.595538 8411.896045 0.963991443 0.923998243 0.91685846 0.971025063 0.981051908 1.028069631 0.965043895 1.197363358 1.002936258 1 13.03821531 ILDPEGLALGAVIAS(ph)SKK ddPTM_HeLa_Curcumin_4h_R1 1 ILDPEGLALGAVIASSKK 18 1 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 0 ILDPEGLALGAVIAS(0.818)S(0.182)KK 84.975 0.0021766 39862000 2617.4 2203.4 2370.6 2745 2432.5 5353.9 6463.2 2160.5 2494.6 2599.6 TRUE FALSE FALSE 2410.230028 2393.852078 2458.456521 2733.641917 2403.494026 4243.440789 6644.539997 2819.226504 2220.948621 2689.935907 0.896017642 0.88992904 0.913946134 1.016247975 0.893513492 1.577524869 2.470148073 1.048064564 0.82565113 1 11.39335608 -5.166535147 4.300464277 0.943992933 1.811377717 0.545412167 0.325808304 0.106238744 3.432312218 0.039692691 0.10636865 6.81E-06 5.166535147 0.867384784 ILDSVGIEADDDRLNK ddPTM_HeLa_Curcumin_4h_R1 4 ILDSVGIEADDDRLNK 16 1 P05387 P05387 RPLP2 60S acidic ribosomal protein P2 0 0 ;;; ;;; 212.39 1.34E-11 273528900 16401 13068.52 16153.6 14455.24 15070.94 18912.6 15185.45 16210.16 15864.37 13645.76 FALSE FALSE TRUE 15102.84354 14198.10464 16752.26663 14395.42805 14891.22888 14989.91357 15611.51286 21152.56316 14124.0883 14119.94914 1.069610336 1.005535111 1.186425422 1.019509908 1.054623408 1.061612433 1.105635204 1.498062277 1.000293143 1 13.78544727 -4.230460821 2.754127637 1.044809866 1.604453883 0.867229468 0.052266742 0.126640515 1.203128884 0.007258077 0.165284097 5.88E-05 4.230460821 0.559644017 SSS(ph)TRS(ph)IDTQTPSVQER ddPTM_HeLa_Curcumin_4h_R1 1 SSSTRSIDTQTPSVQER 17 1 Q86VQ1;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 2 0 S(0.013)S(0.017)S(0.769)T(0.201)RS(0.6)IDT(0.073)QT(0.275)PS(0.052)VQER 124.46 0.0018287 4883100 3426.9 2849.8 2909.5 2909.4 3212.7 3002.1 1681.4 740.88 3969.6 3375.4 TRUE FALSE FALSE 3155.657249 3096.124014 3017.328629 2897.361674 3174.390651 2379.430619 1728.575559 966.7709014 3534.144811 3492.694899 0.903502121 0.886457049 0.863896996 0.829549032 0.908865716 0.681259225 0.494911697 0.276797982 1.011867602 1 11.77012491 -4.456905241 0.768611302 0.943823396 1.09E-17 0.948164594 0.050846259 0.335520796 0.167122219 0.0092823 0.255035715 3.49E-05 4.456905241 -0.943823396 down ILEDNSIPQVK ddPTM_HeLa_Curcumin_4h_R1 1 ILEDNSIPQVK 11 0 P11177-3;P11177-2;P11177 P11177-3 PDHB "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial" 0 0 110.86 9.05E-05 0 1322.5 917.43 1037.3 1155.3 978.8 1423.2 1322.3 1133.5 1167.5 1020.5 FALSE FALSE TRUE 1217.82273 996.7285612 1075.743251 1150.519675 967.1284493 1128.012277 1359.400179 1479.098932 1039.428171 1055.962299 1.153282395 0.943905443 1.01873263 1.089546166 0.915874033 1.068231582 1.287356737 1.400711875 0.984342123 1 10.04434261 -4.665803427 3.1798408 1.049906887 1.381424421 0.76838872 0.070702964 0.103107682 1.984094561 0.011321271 0.053618247 2.16E-05 4.665803427 0.331517534 ILEDVVGVPEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 ILEDVVGVPEKK 12 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 0 1 ILEDVVGVPEK(1)K 149.31 1.84E-05 633840 626.72 876.33 845.87 453.11 494.28 805.43 617.99 470.2 908.02 733.67 FALSE TRUE FALSE 577.1144507 952.0760603 877.2186863 451.2351509 488.3860338 638.3747389 635.3291362 613.5618155 808.4124778 759.1649779 0.760196357 1.254109565 1.155504682 0.594383519 0.643320027 0.84089066 0.83687888 0.808206165 1.064870616 1 9.568269629 -6.248818861 24.98613203 0.935601976 0.749562642 0.393493069 0.160062799 982.3323623 1944823.575 0.027386214 0.045214297 5.64E-07 6.248818861 -0.186039334 ILEGDNGMDS(ph)DMEEEADDGSK ddPTM_HeLa_Curcumin_4h_R1 7 ILEGDNGMDSDMEEEADDGSK 21 0 Q9H8G2;A0A3B3ISJ3;Q9H8G2-2 Q9H8G2 CAAP1 Caspase activity and apoptosis inhibitor 1 1 0 ILEGDNGMDS(1)DMEEEADDGSK;ILEGDNGMDS(1)DMEEEADDGSK;ILEGDNGMDS(1)DMEEEADDGSK;ILEGDNGMDS(1)DMEEEADDGSK;ILEGDNGMDS(1)DMEEEADDGSK;ILEGDNGMDS(1)DMEEEADDGSK;ILEGDNGMDS(1)DMEEEADDGSK ;;;;;; 178.55 4.23E-10 108502500 36860.8 30413 34491.1 34331.4 35271.1 39110.7 33606.7 25411.3 36079 30228.1 TRUE FALSE FALSE 33943.22878 33041.7642 35769.37051 34189.34576 34850.51517 30998.69995 34549.61355 33159.08839 32121.22397 31278.52423 1.085192784 1.056372224 1.143576028 1.093061345 1.114199472 0.991053789 1.104579401 1.060123174 1.0269418 1 14.93288482 -9.14162877 0.773532078 0.996812264 1.082057303 0.312030654 0.039372759 0.583917592 0.597054381 0.03040108 0.007639934 7.22E-10 9.14162877 0.085245039 ILEGGPILPK ddPTM_HeLa_Curcumin_4h_R1 2 ILEGGPILPK 10 0 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 0 0 ; ; 107.15 0.00017579 0 514.55 269.19 258.682 351.41 246.47 719.36 578.64 368.8 523.85 479.06 FALSE FALSE TRUE 473.8228245 292.4575841 268.2689825 349.9559585 243.5310062 570.1566271 594.8750811 481.2454223 466.3849656 495.7072993 0.955852022 0.589980387 0.541184249 0.705972978 0.491279847 1.150188081 1.2000531 0.970825773 0.940847484 1 8.953344693 -7.489411319 23.35466588 0.980523178 0.806534402 0.090627713 0.229935721 365.565917 255107.683 0.043684785 0.04822239 3.24E-08 7.489411319 -0.173988776 ILEGPQQSLSGS(ph)PLQPIPAS(ph)PPPQIPPGLRPR ddPTM_HeLa_Curcumin_4h_R1 2 ILEGPQQSLSGSPLQPIPASPPPQIPPGLRPR 32 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 2 0 ILEGPQQS(0.025)LS(0.035)GS(0.94)PLQPIPAS(1)PPPQIPPGLRPR;ILEGPQQS(0.039)LS(0.049)GS(0.912)PLQPIPAS(1)PPPQIPPGLRPR ; 102.06 1.01E-09 20861000 858.61 519.08 498.18 626.93 554.36 1214.33 595.07 440.61 825.08 431.41 TRUE FALSE FALSE 790.6501125 563.9469622 516.642989 624.3359298 547.7496191 962.4642697 611.7660627 574.9499607 734.5707882 446.4014654 1.771163793 1.263317901 1.157350567 1.398597402 1.227033649 2.156050874 1.37043919 1.287966114 1.645538479 1 8.802197953 -9.578540853 1.361236311 0.999936404 1.491884834 0 0.347198793 0.465866406 1.547478197 0.209242102 0.048844086 2.64E-10 9.578540853 0.49194843 ILEGPQQSLSGS(ph)PLQPIPASPPPQIPPGLRPR ddPTM_HeLa_Curcumin_4h_R1 1 ILEGPQQSLSGSPLQPIPASPPPQIPPGLRPR 32 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 0 ILEGPQQS(0.027)LS(0.313)GS(0.659)PLQPIPASPPPQIPPGLRPR 82.904 4.12E-07 86559000 430.81 408.26 590.23 495.11 512.49 506.92 336.86 231.34 446.56 572.42 TRUE FALSE FALSE 396.7109339 443.5481752 612.104443 493.061366 506.3788915 401.7790778 346.311385 301.874501 397.5734852 592.3115524 0.669767342 0.748842688 1.033416351 0.832435842 0.85491983 0.678323893 0.584677749 0.509654927 0.671223588 1 9.210212414 -13.52287875 0.039330825 2.176954628 3.02E-12 0.130186394 0.15119509 637.4991571 2.002375674 95.52818946 31.62003639 3.00E-14 13.52287875 -2.176954628 ILEGPQQSLSGSPLQPIPAS(ph)PPPQIPPGLRPR ddPTM_HeLa_Curcumin_4h_R1 2 ILEGPQQSLSGSPLQPIPASPPPQIPPGLRPR 32 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 0 ILEGPQQSLSGSPLQPIPAS(1)PPPQIPPGLRPR;ILEGPQQSLSGSPLQPIPAS(1)PPPQIPPGLRPR ; 165.53 4.28E-17 136460000 934.25 731.04 813.77 859.2 653.173 1272.02 985.97 1271.44 1021.38 808.84 TRUE FALSE FALSE 860.3031267 794.2278401 843.9290321 855.6448581 645.3843386 1008.188713 1013.633665 1659.096203 909.3371694 836.9471298 1.02790618 0.948958198 1.008342107 1.022340394 0.771117214 1.20460263 1.211108359 1.982319007 1.086492966 1 9.70899268 -3.967540601 1.410431147 0.997670579 3.080086851 0.901116334 0.097209486 0.470619411 0.484127209 0.012506429 1.686937794 0.00010776 3.967540601 2.082416272 ILELDQFK ddPTM_HeLa_Curcumin_4h_R1 1 ILELDQFK 8 0 P12956;P12956-2;B1AHC9 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 0 123.92 0.0023015 403080 622.92 329.66 372.23 499.46 355.86 544.1 590.23 479.54 482.68 436.41 FALSE FALSE TRUE 573.6152247 358.1543415 386.0251712 497.3933669 351.6166019 431.2475267 606.7902653 625.7495385 429.7312116 451.575215 1.270254003 0.79312223 0.854841361 1.101462946 0.778644598 0.954984934 1.343719153 1.385703904 0.951627098 1 8.818822495 -4.727596986 10.34783451 1.050763915 1.36564996 0.438230974 0.158749758 0.430196567 126.3627627 0.026147772 0.097022828 1.87E-05 4.727596986 0.314886046 ILELT(ph)PEPDRPR ddPTM_HeLa_Curcumin_4h_R1 4 ILELTPEPDRPR 12 1 Q14004-2;Q14004;A0A2R8Y7W5;A0A2R8Y4Z0;A0A2R8YF61 Q14004-2 CDK13 Cyclin-dependent kinase 13 1 0 ILELT(1)PEPDRPR;ILELT(1)PEPDRPR;ILELT(1)PEPDRPR;ILELT(1)PEPDRPR ;;; 145.52 0.00069456 559058000 12479 9579.3 10247.3 10818.2 9712.8 11646.6 9400.6 8784.8 11226.6 9208.4 TRUE FALSE FALSE 11491.27398 10407.29201 10627.07395 10773.43715 9596.981204 9230.963876 9664.355536 11463.24508 9995.070068 9528.391215 1.206003587 1.092240209 1.115306216 1.130666963 1.007198486 0.968785146 1.014269389 1.203061967 1.048977717 1 13.21801693 -5.764259787 24.99932766 1.102713566 1.04021425 0.08982472 0.07651195 144.3717698 1279692.227 0.013837585 0.025911833 1.72E-06 5.764259787 -0.062499316 ILENEKDLEEAEEYKEAR ddPTM_HeLa_Curcumin_4h_R1 3 ILENEKDLEEAEEYKEAR 18 2 E5RIW3;E5RJD8;O75347;E5RHG6 E5RIW3 TBCA Tubulin-specific chaperone A 0 0 ;; ;; 102.15 0.00047548 69193000 7989.4 6529.8 7427.8 7533.8 7272.4 9464.4 7143.5 7568.6 9020.8 7735.2 FALSE FALSE TRUE 7357.03056 7094.206816 7703.080802 7502.627132 7185.68138 7501.376754 7343.927384 9876.231298 8031.240809 8003.997624 0.919169508 0.886332949 0.962404184 0.93735999 0.897761558 0.937203771 0.917532429 1.233912323 1.003403697 1 12.96650502 -4.257939926 24.97151692 0.946364969 1.233912433 0.845876941 0.037535922 107.6322414 768010.802 0.005862064 0.057707098 5.52E-05 4.257939926 0.287547464 SASSSSSSSS(ph)SSDSDVSVK ddPTM_HeLa_Curcumin_4h_R1 1 SASSSSSSSSSSDSDVSVK 19 0 Q7Z4V5-2;Q7Z4V5;Q7Z4V5-4;Q7Z4V5-3;A0A087WT54 Q7Z4V5-2 HDGFRP2 Hepatoma-derived growth factor-related protein 2 1 0 SASSSS(0.001)S(0.001)S(0.001)S(0.046)S(0.317)S(0.317)S(0.317)DSDVSVK 168.05 7.13E-06 4503300 2290 1753.7 2193.5 2165.6 2235.2 2180.7 1207.4 325.12 2081.5 1728 TRUE FALSE FALSE 2108.744084 1905.282014 2274.79304 2156.639321 2208.5467 1728.398238 1241.276394 424.2475913 1853.164658 1788.047871 1.179355496 1.065565438 1.272221553 1.206141824 1.235172019 0.966639801 0.694207585 0.237268587 1.036417809 1 10.80416965 -4.455383488 1.672291686 1.117197066 0.108952534 0.91001402 0.089236589 0.163048578 0.581854455 0.015409054 0.232794108 3.50E-05 4.455383488 -1.008244532 down ILEPDDFLDDLDDEDYEEDTPKR ddPTM_HeLa_Curcumin_4h_R1 1 ILEPDDFLDDLDDEDYEEDTPKR 23 1 J3KMZ8;Q92785 J3KMZ8 DPF2 Zinc finger protein ubi-d4 0 0 54.047 0.019519 5546200 1055.7 1086.5 1036.3 1205.7 1102.5 1534.5 909.24 1048.1 1280.5 1053.7 FALSE FALSE TRUE 972.140231 1180.412219 1074.70619 1200.711133 1089.353408 1216.227403 934.7508273 1367.660865 1140.032354 1090.315997 0.891613288 1.082633129 0.985683227 1.101250588 0.999117147 1.115481573 0.857321025 1.25437109 1.045598118 1 10.0905306 -7.253340734 24.78572545 0.948817386 1.047939496 0.078890326 0.104438981 651.7995586 1994818.559 0.015458509 0.018755338 5.58E-08 7.253340734 0.09912211 ILEQQNSSRT(ph)LEK ddPTM_HeLa_Curcumin_4h_R1 4 ILEQQNSSRTLEK 13 1 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;Q5JXL7 G3V1Q4 SEPT7;DKFZp586I031 Septin-7 1 0 ILEQQNS(0.133)S(0.076)RT(0.791)LEK;ILEQQNS(0.018)S(0.067)RT(0.914)LEK;ILEQQNS(0.072)S(0.153)RT(0.775)LEK;ILEQQNS(0.096)S(0.17)RT(0.734)LEK ;;; 186.42 0.00042748 149415000 8884.1 8020.8 7149.8 8219.1 7869.7 13149 11822.6 6388.8 10343.9 6696.4 TRUE FALSE FALSE 8180.914111 8714.082212 7414.777878 8185.091542 7775.858967 10421.74918 12154.31034 8336.71571 9209.200049 6929.099402 1.180660521 1.257606755 1.070092583 1.181263403 1.122203409 1.504055372 1.754096692 1.203145636 1.329061616 1 12.75845214 -5.262739846 6.093498224 1.108308066 1.515800423 0.442028511 0.157901494 0.072953493 12.76855333 0.020064513 0.048449829 5.46E-06 5.262739846 0.407492357 ILESITVSS(ph)LMATPQDPK ddPTM_HeLa_Curcumin_4h_R1 1 ILESITVSSLMATPQDPK 18 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 ILESIT(0.101)VS(0.104)S(0.735)LMAT(0.06)PQDPK 125.5 0.00028081 14570000 2530.5 2248.8 2219.1 2921 2821.9 4526 4839.8 919.09 3091 2383.7 TRUE FALSE FALSE 2330.208255 2443.176252 2301.341798 2908.913676 2788.250686 3587.256581 4975.591762 1199.31631 2751.925033 2466.533398 0.944730064 0.990530375 0.933026814 1.179353046 1.130432975 1.454371786 2.017240783 0.486235585 1.115705563 1 11.26826911 -5.758356514 1.788655776 0.974087909 1.370848051 0.108322152 0.35567509 0.401101145 2.604554117 0.049042073 0.112795549 1.74E-06 5.758356514 0.396760142 ILESITVSSLMAT(ph)PQDPK ddPTM_HeLa_Curcumin_4h_R1 1 ILESITVSSLMATPQDPK 18 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 ILESIT(0.004)VSS(0.004)LMAT(0.992)PQDPK 161.19 0.0008109 14221000 2536.4 2277.5 2694.3 2518.4 3037.4 4612.9 4567.7 1110.8 2854 2533.6 TRUE FALSE FALSE 2335.641264 2474.356952 2794.153128 2507.979528 3001.180989 3656.132542 4695.857369 1449.477807 2540.92334 2621.642411 0.890907644 0.943819394 1.065802535 0.956644399 1.144771299 1.394596199 1.791189122 0.552889212 0.969210495 1 11.3562552 -5.583257614 3.367745293 0.957095153 1.29887483 0.150402297 0.287720872 0.25507846 5.877895657 0.03830195 0.083012068 2.61E-06 5.583257614 0.341779677 ILGADTSVDLEETGR ddPTM_HeLa_Curcumin_4h_R1 2 ILGADTSVDLEETGR 15 0 P25705;P25705-2;P25705-3;K7ERX7;K7EK77;K7EQH4;K7EJP1;K7ESA0 P25705 ATP5A1 "ATP synthase subunit alpha, mitochondrial" 0 0 ; ; 242.97 3.21E-28 9136600 1231.7 1388.61 1038.16 1232.13 1122.44 1562.63 1266.67 1019.81 1314.6 974.28 FALSE FALSE TRUE 1134.209645 1508.635261 1076.635123 1227.031773 1109.055636 1238.522924 1302.209351 1330.745374 1170.391669 1008.136157 1.125056012 1.496459828 1.067946145 1.217129019 1.100105008 1.228527431 1.291699878 1.320005601 1.160946029 1 9.977474785 -7.765668444 2.168912673 1.041936897 1.235250357 0.208329685 0.121463843 0.221557701 2.171566661 0.022970831 0.022561185 1.72E-08 7.765668444 0.19331346 ILGPGLNK ddPTM_HeLa_Curcumin_4h_R1 1 ILGPGLNK 8 0 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 0 103.29 0.010412 7208500 8190.5 7422.6 7500.8 8260 7735.5 8704.9 6371.7 5468.3 8239.8 7867.3 FALSE FALSE TRUE 7542.213282 8064.17647 7778.786246 8225.822309 7643.259215 6899.405616 6550.472753 7135.559497 7335.914555 8140.688089 0.926483511 0.990601333 0.955544072 1.010457865 0.938895967 0.847521185 0.804658363 0.876530266 0.901141829 1 12.99093503 -5.313808028 3.537894178 0.968716791 0.837153641 0.701260351 0.035321792 0.086208671 2.188169545 0.004818527 0.01194025 4.86E-06 5.313808028 -0.131563149 AAS(ph)PVLLSSNSQK ddPTM_HeLa_Curcumin_4h_R1 1 AASPVLLSSNSQK 13 0 G3V1Z7;P41970 G3V1Z7 ELK3 ETS domain-containing protein Elk-3 1 0 AAS(1)PVLLSSNSQK 237.59 9.86E-27 17030000 2110.3 1617.3 1887.7 1672 1736.3 2879.1 1375.8 599.43 2080.2 1824.4 TRUE FALSE FALSE 1943.267528 1757.092205 1957.659823 1665.081707 1715.595757 2281.942206 1414.401245 782.1934476 1852.007264 1887.797764 1.029383319 0.930762944 1.037007173 0.882023349 0.908781538 1.20878531 0.749233457 0.41434176 0.981041137 1 10.8824885 -4.454598505 3.525453484 1.003464291 0.43139378 0.804384807 0.089048587 0.070766335 1.578805665 0.011465867 0.079087762 3.51E-05 4.454598505 -0.572070511 down ESS(ph)PIPSPTSDRK ddPTM_HeLa_Curcumin_4h_R1 1 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 ES(0.021)S(0.979)PIPSPTSDRK 116.79 0.0013139 14323000 2108.5 1459.7 1464.8 1566.7 1906.3 2603.7 1953.9 3922.7 2223.3 1913.7 TRUE FALSE FALSE 1941.61 1585.869964 1519.086777 1560.217411 1883.568618 2063.66327 2008.721175 5118.713172 1979.409552 1980.200933 0.980511608 0.800863154 0.767137694 0.787908633 0.951200753 1.042148419 1.014402701 2.58494635 0.999600354 1 10.95143111 -4.259825143 5.055635881 0.948782874 2.664682817 0.96273244 0.097854835 0.025264351 2.04188016 0.015609696 0.150769805 5.50E-05 4.259825143 1.715899943 up ILIANTGMDTDK(ac)IK ddPTM_HeLa_Curcumin_4h_R1 1 ILIANTGMDTDKIK 14 1 F5GWF6;P78371;F8VQ14;P78371-2 F5GWF6 CCT2 T-complex protein 1 subunit beta 0 1 ILIANTGMDTDK(1)IK 178.32 1.44E-43 0 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 ILISLATGHR ddPTM_HeLa_Curcumin_4h_R1 1 ILISLATGHR 10 0 E7EMC6;E5RK69;P08133-2;P08133 E7EMC6 ANXA6 Annexin;Annexin A6 0 0 134.23 0.00024928 1905000 745.78 687.46 1014.3 758.57 1290.8 1426.6 1034.4 1071.9 828.91 713.67 FALSE FALSE TRUE 686.7507261 746.8809791 1051.89085 755.4312383 1275.408053 1130.707079 1063.42248 1398.717376 737.9806468 738.4699794 0.929964312 1.011389765 1.424419245 1.022968109 1.72709533 1.531148334 1.440034815 1.894074796 0.99933737 1 9.528395463 -6.000535288 0.760265685 0.960442263 1.695411692 0.70249971 0.180997896 0.258921965 0.282844772 0.032271327 0.098119067 9.99E-07 6.000535288 0.734969428 ILIVTQT(ph)PHYMR ddPTM_HeLa_Curcumin_4h_R1 3 ILIVTQTPHYMR 12 0 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 0 ILIVT(0.371)QT(0.629)PHYMR;ILIVT(0.217)QT(0.783)PHYMR;ILIVT(0.001)QT(0.999)PHYMR ;; 182.37 0.00021757 171666000 11013 9612.13 9920.6 11296.5 10427.79 14033.3 12441.4 7366.45 10590.8 10216.4 TRUE FALSE FALSE 10141.30943 10442.95969 10288.26616 11249.75808 10303.44541 11122.63539 12790.4722 9612.446694 9429.015737 10571.41914 0.95931391 0.987848419 0.973215235 1.064167254 0.974651112 1.052142124 1.209910612 0.909286309 0.891934717 1 13.36788144 -5.773384143 1.141435055 0.980778979 1.064966084 0.166022389 0.0785151 0.599449063 1.531415631 0.011063373 0.031356409 1.69E-06 5.773384143 0.084187104 ILK(ac)CAGNEDIITLR ddPTM_HeLa_Curcumin_4h_R1 1 ILKCAGNEDIITLR 14 1 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 1 ILK(1)CAGNEDIITLR 128.68 0.0019071 747270 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 ILLDHEK(ac)EWK ddPTM_HeLa_Curcumin_4h_R1 1 ILLDHEKEWK 10 1 P54136-2;P54136 P54136-2 RARS "Arginine--tRNA ligase, cytoplasmic" 0 1 ILLDHEK(1)EWK 69.672 0.011515 0 489.81 510.85 321.33 587.38 481.07 1004.4 624.37 796.38 1017.4 387.58 FALSE TRUE FALSE 451.0410217 555.0055977 333.2387725 584.9495772 475.3335544 796.0761181 641.8881418 1039.192596 905.7937654 401.0483762 1.124654901 1.383886909 0.830919142 1.458551167 1.185227476 1.984987761 1.600525473 2.591190135 2.25856485 1 8.647632461 -1 0.40482224 1.043362801 25.7223646 0.321309294 0.447206377 18.00210697 0.211037604 0.048569331 359.537604 0.1 1 24.67900179 ILLDPNS(ph)EEVSEKDAK ddPTM_HeLa_Curcumin_4h_R1 1 ILLDPNSEEVSEKDAK 16 1 A0A0U1RQZ9;F6VDE0;P51531-2;P51531 A0A0U1RQZ9 SMARCA2 Probable global transcription activator SNF2L2 1 0 ILLDPNS(0.999)EEVS(0.001)EKDAK 67.648 0.012392 4143900 935.47 834.98 757.53 1048.1 1068.7 1180.6 818.19 870.72 888.15 793.97 TRUE FALSE FALSE 861.4265624 907.1519506 785.6047282 1043.76324 1055.95645 935.7302519 841.1462094 1136.19852 790.722167 821.5603984 1.048524934 1.104181692 0.956234903 1.270464402 1.285305928 1.138967085 1.02383977 1.382976251 0.962463829 1 9.682222831 -6.259888288 24.99947515 1.026338188 1.208487396 0.523339724 0.0976506 92.9518788 1498134.908 0.013988639 0.022411907 5.50E-07 6.259888288 0.182149208 ILLDPNSEEVS(ph)EK ddPTM_HeLa_Curcumin_4h_R1 1 ILLDPNSEEVSEK 13 0 A0A0U1RQZ9;F6VDE0;P51531-2;P51531 A0A0U1RQZ9 SMARCA2 Probable global transcription activator SNF2L2 1 0 ILLDPNS(0.003)EEVS(0.997)EK 98.353 0.0078861 3052800 4458.6 3563 3665.8 4094.5 3924.6 4606.5 4465.8 3583 4745.7 4206.9 TRUE FALSE FALSE 4105.697105 3870.969844 3801.657773 4077.558044 3877.801708 3651.059974 4591.098329 4675.440206 4225.108583 4353.089462 0.943168557 0.889246563 0.873324062 0.936704398 0.890815992 0.838728449 1.05467585 1.074051027 0.970599989 1 12.08782395 -4.603981484 10.89346726 0.943831354 1.069207319 0.530570549 0.050749855 0.288778881 36.56451619 0.008501236 0.031857283 2.49E-05 4.603981484 0.125375964 ILLLEAGPK ddPTM_HeLa_Curcumin_4h_R1 1 ILLLEAGPK 9 0 G3V2L5;G3V4A6;G3V434;Q9Y2Z9-3;Q9Y2Z9 G3V2L5 COQ6 "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial" 0 0 100.45 0.0042437 0 425.12 4656.2 564.04 1338.3 657.54 536.97 488.47 542.95 690.57 1247.1 FALSE FALSE TRUE 391.4713034 5058.66118 584.9438186 1332.762469 649.699265 425.5963691 502.1751536 708.4929556 614.8161987 1290.436632 0.303363446 3.920115916 0.453291393 1.032799625 0.503472428 0.329808034 0.389151347 0.549033512 0.476440441 1 10.33364358 -5.686730893 5.201366588 0.938521841 0.420521012 0.089910371 0.989112925 0.54295848 26.39873584 0.147123086 0.296695266 2.06E-06 5.686730893 -0.518000829 ILLLFGETELS(ph)PTATPR ddPTM_HeLa_Curcumin_4h_R1 1 ILLLFGETELSPTATPR 17 0 Q8NCF5;H3BSZ7;Q8NCF5-3;Q8NCF5-2 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 0 ILLLFGET(0.001)ELS(0.886)PT(0.105)AT(0.008)PR 162.46 0.00013188 70842000 1435.5 1101.4 1288.3 1119.7 1382.4 1706.6 1393.9 1250.2 1493.4 1093.5 TRUE FALSE FALSE 1321.87866 1196.600108 1336.045531 1115.066978 1365.915783 1352.631923 1433.009083 1631.380225 1329.577756 1131.499044 1.168254333 1.057535236 1.180774777 0.985477614 1.207173608 1.195433554 1.266469548 1.441786658 1.175058666 1 10.14401965 -1 0.426472965 1.072009126 8.154489621 0.671057631 0.072749947 29.22921376 0.330282861 0.017052626 179.1583367 0.1 1 7.082480495 ILLTEPPMNPTK ddPTM_HeLa_Curcumin_4h_R1 3 ILLTEPPMNPTK 12 0 P61160;F5H6T1;P61160-2 P61160 ACTR2 Actin-related protein 2 0 0 ;; ;; 151.22 4.01E-05 2270720 3673.9 3103.86 2762.9 3187.77 3564.67 4012.12 3083.11 2798.2 3487.02 3263 FALSE FALSE TRUE 3383.106938 3372.143828 2865.295504 3174.579852 3522.163638 3179.961086 3169.613769 3651.358299 3104.50263 3376.389007 1.001989679 0.998742687 0.848627187 0.940229294 1.043174714 0.941823078 0.938758467 1.081438866 0.919474214 1 11.72126542 -6.951050767 24.99992452 1.000910012 0.962229656 0 0.064617013 213.8977132 109243.7014 0.009275214 0.012190019 1.12E-07 6.951050767 -0.038680356 ILLVDS(ph)PGMGNADDEQQEEGTSSK ddPTM_HeLa_Curcumin_4h_R1 4 ILLVDSPGMGNADDEQQEEGTSSK 24 0 Q9UKN8 Q9UKN8 GTF3C4 General transcription factor 3C polypeptide 4 1 0 ILLVDS(1)PGMGNADDEQQEEGTSSK;ILLVDS(1)PGMGNADDEQQEEGTSSK;ILLVDS(1)PGMGNADDEQQEEGTSSK;ILLVDS(1)PGMGNADDEQQEEGTSSK ;;; 179.17 2.23E-11 68314000 19409.4 15810.1 17178.6 18228.4 17125.4 20896.8 16246.9 10928.9 19291.8 18060.9 TRUE FALSE FALSE 17873.12551 17176.6546 17815.25403 18152.97571 16921.19079 16562.56812 16702.74429 14261.0713 17175.53781 18688.51493 0.956369491 0.919102168 0.953272857 0.971343939 0.905432607 0.886243138 0.893743797 0.763092806 0.91904241 1 14.18986431 -2.046658043 0.326726015 0.984317758 4.48E-14 0.717431076 0.03277867 7.417128722 0.176860083 0.008903072 3.931058479 0.008981357 2.046658043 -0.984317758 ILMEHIHK ddPTM_HeLa_Curcumin_4h_R1 1 ILMEHIHK 8 0 J3QR09;J3KTE4;P84098 J3QR09 RPL19 Ribosomal protein L19;60S ribosomal protein L19 0 0 94.302 0.0053573 7939600 6219.4 4537.4 5399.3 5570.3 5499.5 6000.1 5657.7 5032.3 5878.3 5588.7 FALSE FALSE TRUE 5727.127927 4929.592638 5599.402808 5547.251575 5433.922054 4755.611625 5816.439835 6566.625104 5233.465197 5782.906909 0.990354508 0.852441984 0.968267844 0.959249675 0.939652348 0.822356593 1.005798628 1.135523225 0.904988664 1 12.49757916 -7.487523021 24.85549807 0.995744684 0.949571163 0 0.084943338 929.3090869 653321.4575 0.013715756 0.015237674 3.25E-08 7.487523021 -0.046173521 ILMSK(ac)PVLSGGTGR ddPTM_HeLa_Curcumin_4h_R1 2 ILMSKPVLSGGTGR 14 1 Q9ULU4-9;Q9ULU4-11;Q9ULU4-23;Q9ULU4-21;Q9ULU4;Q9ULU4-5;H7C4X9;A0A087WYS3;A0A087WVZ6;Q9ULU4-10;Q9ULU4-13;Q9ULU4-20;Q9ULU4-12;Q9ULU4-7;Q9ULU4-19;Q9ULU4-16;Q9ULU4-22;Q9ULU4-18;Q9ULU4-14;Q9ULU4-15;Q9ULU4-6;Q9ULU4-3;Q9ULU4-4;A0A087WV57;Q9ULU4-8;Q9ULU4-17 Q9ULU4-9 ZMYND8 Protein kinase C-binding protein 1 0 1 ; ILMSK(1)PVLSGGTGR;ILMSK(1)PVLSGGTGR 128.68 0.0019071 2069080 290.475 230.14 257.78 355.32 445.88 353.232 175.83 264.3 325.237 268.76 FALSE TRUE FALSE 267.4835972 250.0322761 267.3335536 353.84978 440.5631722 279.9677015 180.7633166 344.8838533 289.5593148 278.09939 0.961827343 0.899075241 0.96128781 1.272386034 1.584193235 1.006718143 0.649995372 1.240146026 1.041208018 1 8.11945677 -6.295671641 23.7885087 0.972569442 1.138956868 0.137172166 0.222251256 606.5356161 421489.4212 0.035438409 0.054135531 5.06E-07 6.295671641 0.166387425 ILMVGLDAAGK ddPTM_HeLa_Curcumin_4h_R1 3 ILMVGLDAAGK 11 0 C9JPM4;P18085;F5H0C7;F5H1V1;F5H6T5;F8WDB3;F5H423;P84077;P61204;C9J1Z8;P61204-2;P84085 C9JPM4;F5H423 ARF4;ARF3;ARF1;ARF5 ADP-ribosylation factor 4;ADP-ribosylation factor 1;ADP-ribosylation factor 3;ADP-ribosylation factor 5 0 0 ;; ;; 113.71 0.0033976 3411710 2993.57 3053.48 2887.02 2528.58 2960.32 4176.56 2981.31 2890.43 2654.03 2324.68 FALSE FALSE TRUE 2756.625776 3317.409205 2994.015501 2518.117406 2925.020117 3310.294376 3064.957535 3771.708801 2362.889549 2405.462457 1.145985782 1.379114937 1.244673552 1.046832969 1.215990758 1.376157157 1.274165608 1.567976582 0.98230157 1 11.23209857 -1 0.118561106 0.900575973 2.60211868 0.614166878 0.11017476 49.08231228 0.401358833 0.520766692 13.82981747 0.1 1 1.701542707 ILNPEEIEK ddPTM_HeLa_Curcumin_4h_R1 1 ILNPEEIEK 9 0 O14818;O14818-2;H0Y586 O14818 PSMA7 Proteasome subunit alpha type-7 0 0 128.27 0.00072278 3931000 3086.9 2302.2 2860 3014.8 3529.8 3590.2 3102.6 3152.6 3024.2 2791.9 FALSE FALSE TRUE 2842.568608 2501.19191 2965.994116 3002.325556 3487.70944 2845.55205 3189.650606 4113.813227 2692.452826 2888.918317 0.983956033 0.86578838 1.026679812 1.039255952 1.207271739 0.984988753 1.104098578 1.423997765 0.931993407 1 11.4963137 -1 0.742597946 0.993404834 70.31138738 0.704921714 0.08178522 138.6658989 0.578967758 0.012774812 16080.65438 0.1 1 69.31798255 ILPDILK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 ILPDILKK 8 1 C9JMA6;P0DN79;P35520;P35520-2 C9JMA6 CBS Cystathionine beta-synthase 0 1 ILPDILK(1)K 96.711 0.0023775 0 577.08 768.73 628.6 417.86 594.54 899.14 785.79 784.48 954.54 670.71 FALSE TRUE FALSE 531.4035091 835.1755958 651.896469 416.131006 587.4504988 712.6482286 807.8371526 1023.664341 849.8293501 694.0171226 0.765692217 1.203393358 0.939308913 0.599597607 0.846449576 1.026845312 1.164001761 1.474984273 1.224507757 1 9.438827447 -4.456983441 1.573678424 0.891891028 1.565345483 0.429856032 0.182080714 0.410814617 1.253033936 0.02343136 0.3767724 3.49E-05 4.456983441 0.673454456 ILPGSMIVSS(ph)DDTVDSTIDR ddPTM_HeLa_Curcumin_4h_R1 2 ILPGSMIVSSDDTVDSTIDR 20 0 Q9UK59-2;Q9UK59 Q9UK59-2 DBR1 Lariat debranching enzyme 1 0 ILPGSMIVS(0.255)S(0.734)DDT(0.011)VDSTIDR;ILPGSMIVS(0.311)S(0.678)DDT(0.011)VDSTIDR ; 137.91 0.00010309 16299000 2996.1 2726.9 3184.9 3418.8 3665.5 2913.7 1714.79 1105.8 3227.6 2456.4 TRUE FALSE FALSE 2758.955524 2962.601085 3302.935196 3404.653911 3621.791307 2309.365776 1762.902392 1442.95333 2873.540355 2541.759717 1.085450959 1.16557087 1.299467913 1.339486927 1.424914905 0.908569665 0.693575549 0.567698559 1.130531866 1 11.31161194 -4.862778239 3.181628889 1.117124911 0.615498032 0.699899861 0.143744948 0.134360924 2.658012175 0.024623223 0.090851416 1.37E-05 4.862778239 -0.501626879 ILPTS(ph)ETK ddPTM_HeLa_Curcumin_4h_R1 1 ILPTSETK 8 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 0 ILPT(0.189)S(0.808)ET(0.003)K 99.973 0.015068 25878000 10233 8636.1 9494.1 9825 10074 14049 14041 4287.9 8533.6 7564.6 TRUE FALSE FALSE 9423.047252 9382.566002 9845.959698 9784.346753 9953.87413 11135.07904 14434.95267 5595.260971 7597.48543 7827.469287 1.203843402 1.198671711 1.257872671 1.250001296 1.271659302 1.422564385 1.844140442 0.714823753 0.970618364 1 12.93433023 -8.005935041 0.364544794 0.974809237 1.358090712 0.16366835 0.258931818 1.609304992 0.560648722 0.249022221 0.141420373 9.86E-09 8.005935041 0.383281475 ILQDGGLQVVEK ddPTM_HeLa_Curcumin_4h_R1 2 ILQDGGLQVVEK 12 0 A0A286YF22;A0A2C9F2M7;O43175;A0A286YFL2;A0A286YFA2;A0A286YFM8;A0A286YER3;A0A286YFC8;A0A286YFB2;A0A286YF34;A0A286YFF3;A0A286YFK5 A0A286YF22 PHGDH D-3-phosphoglycerate dehydrogenase 0 0 ; ; 182.08 1.69E-09 1934170 1158.24 808.4 1153.7 1245.39 1060.25 1615.71 1174.36 1125.89 1313.28 1335.02 FALSE FALSE TRUE 1066.564082 878.2744938 1196.457137 1240.236906 1047.607211 1280.593533 1207.309381 1469.168678 1169.21647 1381.411846 0.772082623 0.635780341 0.866111827 0.897803874 0.7583598 0.927017918 0.873967734 1.063526915 0.846392387 1 10.43192778 -3.841673457 1.617562682 0.86218941 1.429274678 0.298471052 0.09750718 4.679171322 4.633512803 0.017380464 5.83204229 0.000143988 3.841673457 0.567085268 ILQVSFK ddPTM_HeLa_Curcumin_4h_R1 1 ILQVSFK 7 0 Q15717;Q15717-2 Q15717 ELAVL1 ELAV-like protein 1 0 0 113.5 0.011599 856490 1249.7 638.13 926.02 708.4 617.13 1756.6 1301.9 1084.3 869.56 954.76 FALSE FALSE TRUE 1150.784926 693.2871137 960.3391158 705.4688285 609.7711278 1392.261359 1338.42781 1414.898078 774.1714435 987.9378389 1.164835358 0.701751756 0.972064312 0.714082203 0.617216088 1.409260081 1.354769255 1.432173182 0.783623638 1 9.94827646 -5.214327738 24.98478234 0.987889924 1.394338013 0.573623568 0.192586664 295.8839251 156916.0602 0.029738078 0.075817274 6.10E-06 5.214327738 0.406448089 ILS(ph)DVTHSAVFGVPASK ddPTM_HeLa_Curcumin_4h_R1 1 ILSDVTHSAVFGVPASK 17 0 Q2M2I8-2;Q2M2I8;E9PG46 Q2M2I8-2 AAK1 AP2-associated protein kinase 1 1 0 ILS(0.758)DVT(0.241)HS(0.002)AVFGVPASK 108.25 0.0006112 269920000 8738.8 7272.3 8596.3 9062 9011.5 9093.4 7267.8 5692.8 9015 8764.7 TRUE FALSE FALSE 8047.114759 7900.885207 8914.88644 9024.503845 8904.043748 7207.326336 7471.714908 7428.508514 8026.077054 9069.272673 0.887294389 0.871170764 0.982977 0.995063681 0.981781458 0.794697281 0.823849406 0.819085365 0.884974721 1 13.14677114 -5.257686136 24.96013616 0.948336331 0.813674549 0.625905649 0.046216247 178.7570961 1188778.61 0.007719388 0.018883214 5.52E-06 5.257686136 -0.134661782 ILSDDVPIRDYR ddPTM_HeLa_Curcumin_4h_R1 2 ILSDDVPIRDYR 12 1 P54725-2;P54725-3;P54725;A0A494C0B4;K7ENJ0;K7ELW1 P54725-2 RAD23A UV excision repair protein RAD23 homolog A 0 0 ; ; 98.754 0.0086203 18538300 8286.1 6912.3 7605.7 7644.7 7483.6 9879.8 7974.4 7779.1 7842.1 7683.3 FALSE FALSE TRUE 7630.246442 7509.768411 7887.573933 7613.068257 7394.362958 7830.618112 8198.140202 10150.91178 6981.84125 7950.294103 0.959743922 0.944590013 0.992110962 0.957583224 0.930074141 0.984946973 1.031174457 1.276797015 0.878186537 1 12.95679252 -4.227772175 2.358257021 0.973701089 1.365392728 0.870189292 0.03672418 0.115011377 0.702677321 0.003494035 0.094932204 5.92E-05 4.227772175 0.391691638 ILSDVT(ph)HSAVFGVPASK ddPTM_HeLa_Curcumin_4h_R1 1 ILSDVTHSAVFGVPASK 17 0 Q2M2I8-2;Q2M2I8;E9PG46 Q2M2I8-2 AAK1 AP2-associated protein kinase 1 1 0 ILS(0.318)DVT(0.681)HSAVFGVPASK 118.05 0.00068953 306170000 12394 9874.1 10726 11434 12257 11687 9697.2 7596 11242 11309 TRUE FALSE FALSE 11413.00182 10727.57321 11123.515 11386.68914 12110.84328 9262.98446 9969.277333 9911.985432 10008.78073 11701.98691 0.975304614 0.916730918 0.950566351 0.973056048 1.034939056 0.791573648 0.85193031 0.847034398 0.855306095 1 13.51446589 -5.258403618 24.99996643 0.981186798 0.832354533 0.534843114 0.051520746 85.7256235 705958.7257 0.00488877 0.011903226 5.52E-06 5.258403618 -0.148832265 ILSEVT(ph)PDQSKPEN ddPTM_HeLa_Curcumin_4h_R1 2 ILSEVTPDQSKPEN 14 1 O43482 O43482 OIP5 Protein Mis18-beta 1 0 ILSEVT(0.795)PDQS(0.205)KPEN;ILSEVT(0.988)PDQS(0.012)KPEN ; 211.51 1.50E-40 2919000 3892.6 3239.8 3186.9 3647.9 3241.2 3573 2829.1 2036.89 3696.9 3530.3 TRUE FALSE FALSE 3584.496603 3519.833876 3305.009317 3632.805956 3202.550807 2831.919524 2908.476932 2657.928384 3291.359319 3652.977662 0.981253359 0.963551984 0.904743917 0.99447801 0.876695973 0.775235927 0.796193462 0.727605978 0.901007239 1 11.83485722 -5.265873488 0.719019067 0.990373632 0.704793548 0.784412598 0.042950271 0.232507875 0.171141137 0.005667661 0.041131448 5.42E-06 5.265873488 -0.285580084 ILSGVVTK ddPTM_HeLa_Curcumin_4h_R1 1 ILSGVVTK 8 0 P62280;M0QZC5 P62280 RPS11 40S ribosomal protein S11 0 0 101.54 0.012007 3788800 5454.4 4393.9 4626.5 4860.2 5052 5321.6 4821.1 4801.3 4890.4 4302.1 FALSE FALSE TRUE 5022.678485 4773.689137 4797.96216 4840.08978 4991.7582 4217.840173 4956.367091 6265.194268 4353.935355 4451.597655 1.128286713 1.072354132 1.077806786 1.087270269 1.121340828 0.947489082 1.113390624 1.407403533 0.978061292 1 12.12010749 -4.28005789 4.018350528 1.063163669 1.432208286 0.769360133 0.057836873 0.079273745 2.6510233 0.008233285 0.082037769 5.25E-05 4.28005789 0.369044616 ILSLSEEGS(ph)LER ddPTM_HeLa_Curcumin_4h_R1 2 ILSLSEEGSLER 12 0 A0A2R8YGD3;Q9Y4G8;A0A2R8Y661;H0Y8H7 A0A2R8YGD3 RAPGEF2 Rap guanine nucleotide exchange factor 2 1 0 ILS(0.001)LS(0.403)EEGS(0.595)LER;ILS(0.001)LS(0.078)EEGS(0.922)LER ; 187.78 1.46E-05 7329900 1869.78 1479.84 1998.33 1664.4 1605.63 2362.81 1548.86 691.94 1814.16 1447.81 TRUE FALSE FALSE 1721.78494 1607.750776 2072.389868 1657.513154 1586.483911 1872.736572 1592.316843 902.9093207 1615.151187 1498.12129 1.14929609 1.073177977 1.383325824 1.106394499 1.058982288 1.250056711 1.062875786 0.602694406 1.078117772 1 10.54893872 -4.268258745 4.655844491 1.107283112 0.574686223 0.683358478 0.106960194 0.087743899 5.100703262 0.015968248 0.150293372 5.39E-05 4.268258745 -0.532596889 ILSPS(ph)MASK ddPTM_HeLa_Curcumin_4h_R1 1 ILSPSMASK 9 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91;Q8IX09;C9JWI7 A0A494BZT8 TACC3;ERIC-1s Transforming acidic coiled-coil-containing protein 3 1 0 ILS(0.292)PS(0.707)MAS(0.001)K 101.3 0.012371 106660000 4367.5 3627.3 3602.6 3771.6 4054.5 6690.5 6023.8 4552.3 3629.3 3343.4 TRUE FALSE FALSE 4021.807766 3940.827649 3736.115525 3755.994119 4006.152736 5302.814883 6192.811616 5940.275314 3231.17487 3459.582901 1.162512326 1.139104846 1.079932359 1.08567831 1.157987205 1.532790233 1.790045735 1.717049565 0.933978159 1 11.7563824 -5.152342183 2.243533485 1.084280079 1.757386447 0.94725152 0.066385702 0.047788015 0.462007435 0.009712802 0.031753549 7.04E-06 5.152342183 0.673106368 ILTEAEIDAHLVALAERD ddPTM_HeLa_Curcumin_4h_R1 2 ILTEAEIDAHLVALAERD 18 1 G3V5Z7;P60900-2;P60900;P60900-3;H0YJC4 G3V5Z7 PSMA6 Proteasome subunit alpha type;Proteasome subunit alpha type-6 0 0 ; ; 126.14 0.00033138 14514800 4403.1 3402.9 3964.8 3589.5 3933.8 5465 4458.6 4277.5 4249.9 4114 FALSE FALSE TRUE 4054.589989 3697.031513 4111.738976 3574.6476 3886.892004 4331.497397 4583.696316 5581.690059 3783.696603 4256.961194 0.952461111 0.868467281 0.965885943 0.839718155 0.913067286 1.017509251 1.076753136 1.311191201 0.888825721 1 12.05560822 -4.243523677 1.530188013 0.95441736 1.458024012 0.816115348 0.05535069 0.401872581 0.828123406 0.008510104 0.30770177 5.71E-05 4.243523677 0.503606652 IMATPEQVGK ddPTM_HeLa_Curcumin_4h_R1 1 IMATPEQVGK 10 0 P12956;P12956-2;B1AHC9 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 0 111.65 0.0048619 2994600 3037.2 2190.5 2548.1 2111.1 2513.7 3016.6 2183.8 2109.3 2735.1 2834.4 FALSE FALSE TRUE 2796.802415 2379.837059 2642.534828 2102.364828 2483.725769 2390.923156 2245.071551 2752.41586 2435.066373 2932.895189 0.953597805 0.811429289 0.900998726 0.716822352 0.846851186 0.815209205 0.765479639 0.938463764 0.830260277 1 11.5181098 -7.353264604 1.646026019 0.984363142 0.820319224 0.147093809 0.077823974 0.165462123 0.857333341 0.010767921 0.012327414 4.43E-08 7.353264604 -0.164043917 IMATPEQVGK(ac)MK ddPTM_HeLa_Curcumin_4h_R1 7 IMATPEQVGKMK 12 1 P12956;P12956-2;B1AHC9 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 1 ;;;;;; IMATPEQVGK(1)MK;IMATPEQVGK(1)MK;IMATPEQVGK(1)MK;IMATPEQVGK(1)MK;IMATPEQVGK(1)MK;IMATPEQVGK(1)MK;IMATPEQVGK(1)MK 221.59 8.44E-29 75059100 20812.1 16222.6 18704.56 18124 18042.12 22595.3 19750.5 17641.79 20113.63 17212.53 FALSE TRUE FALSE 19164.80032 17624.80926 19397.76745 18049.00769 17826.9795 17908.78008 20304.64587 23020.69056 17907.21511 17810.66414 1.076029517 0.989564966 1.089109721 1.01338207 1.000916045 1.005508831 1.140027442 1.292522861 1.005420964 1 14.12045369 -4.419986313 2.576096018 1.031468016 1.307200615 0.860721134 0.033739793 0.106104864 1.096347657 0.005247823 0.053490818 3.80E-05 4.419986313 0.2757326 IMEET(ph)SGMEEEEEEESIAAVPGR ddPTM_HeLa_Curcumin_4h_R1 1 IMEETSGMEEEEEEESIAAVPGR 23 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 0 IMEET(0.548)S(0.452)GMEEEEEEESIAAVPGR 78.484 0.00057556 1918000 628.75 502.43 612.17 769.52 743.02 522.06 403.24 524.46 652.68 429.02 TRUE FALSE FALSE 578.983774 545.8578104 634.8575587 766.3359301 734.1599718 413.7788712 414.5538291 684.3654397 581.0826369 443.9284131 1.304227792 1.229607735 1.430089943 1.726260153 1.653780092 0.932084676 0.933830359 1.54161216 1.308955723 1 8.794183239 -8.836460432 0.712176126 0.999474051 1.342852251 0.029378356 0.269139896 0.968133071 0.921649286 0.180031682 0.059908951 1.46E-09 8.836460432 0.3433782 IMGPNYTPGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 IMGPNYTPGKK 11 1 P13639 P13639 EEF2 Elongation factor 2 0 1 IMGPNYTPGK(1)K 116.23 0.00087464 3282300 1083.4 1514.9 1314.6 1116.2 2275.7 2190.8 1701.4 1296.8 2122.1 1039.9 FALSE TRUE FALSE 997.6477468 1645.841206 1363.320232 1111.58146 2248.563764 1736.403385 1749.136705 1692.18835 1889.310939 1076.036448 0.927150515 1.529540388 1.266983322 1.033033279 2.089672491 1.613703131 1.625536671 1.572612484 1.75580571 1 10.07151123 -6.524303129 0.78719145 0.961824093 1.687197509 0.011390477 0.353519444 0.312913781 0.387851616 0.051121115 0.099332791 2.99E-07 6.524303129 0.725373417 IMIAMLDRK ddPTM_HeLa_Curcumin_4h_R1 1 IMIAMLDRK 9 1 C9JV47 C9JV47 GCA 0 0 69.825 0.019337 0 249.49 272.16 180.52 214.98 394.14 810.05 316.2 346.16 282.78 219.49 FALSE FALSE TRUE 229.7426032 295.6842977 187.21023 214.0904697 389.4401379 642.0364989 325.071721 451.7025905 251.7597415 227.1172612 1.011559412 1.301901477 0.824288868 0.942642882 1.714709555 2.826894335 1.431294651 1.988851874 1.108501134 1 7.827293546 -5.641477873 4.387629209 1.011996528 2.052548479 0.667455174 0.337565803 0.088370555 2.972093908 0.045440112 0.093197835 2.28E-06 5.641477873 1.040551951 IMK(ac)DILEK ddPTM_HeLa_Curcumin_4h_R1 1 IMKDILEK 8 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 1 IMK(1)DILEK 98.249 0.014754 1292800 657.23 956.1 736.37 846.01 1428.8 1308.2 1121 1314.2 1646.1 795.77 FALSE TRUE FALSE 605.209552 1038.741024 763.66052 842.5094348 1411.762493 1036.864574 1152.452243 1714.89353 1465.526948 823.4229483 0.734992331 1.261491468 0.927421954 1.023179444 1.714504674 1.259212627 1.39958723 2.082639953 1.779798524 1 9.685489846 -1.284955455 0.33206347 0.86961679 10.54707716 0.217335407 0.359245189 17.82125943 0.270704679 0.073086387 104.3030359 0.051885325 1.284955455 9.677460374 IMLFTNEDNPHGNDSAK ddPTM_HeLa_Curcumin_4h_R1 2 IMLFTNEDNPHGNDSAK 17 0 P12956;P12956-2;B1AHC9 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 0 ; ; 145.33 0.0005923 4117400 2249.4 1533.34 2013.59 2131.8 2108.22 2598.1 2320.6 1704.12 2573 1923.53 FALSE FALSE TRUE 2071.357616 1665.875077 2088.215417 2122.979176 2083.080853 2059.224773 2385.70979 2223.698343 2290.748337 1990.372524 1.040688409 0.836966476 1.04915808 1.066624037 1.046578381 1.034592644 1.198624761 1.11722721 1.150914369 1 10.95882276 -5.001018188 1.105520267 1.008768058 1.168519862 0.252609005 0.079759669 0.522822036 0.988363594 0.010122748 0.0713203 9.98E-06 5.001018188 0.159751805 IMNT(ph)FS(ph)VMPSPK ddPTM_HeLa_Curcumin_4h_R1 1 IMNTFSVMPSPK 12 0 Q9BVA1;Q13885;Q9BUF5;K7ESM5;K7ES63 Q9BVA1;Q9BUF5 TUBB2B;TUBB2A;TUBB6 Tubulin beta-2B chain;Tubulin beta-2A chain;Tubulin beta-6 chain 2 0 IMNT(1)FS(1)VMPSPK 65.809 0.0086711 0 1083.2 931.69 834.48 832.39 919.51 1317.1 1060.4 395.02 841.56 1023.4 TRUE FALSE FALSE 997.463577 1012.221132 865.4065629 828.9457907 908.5454438 1043.918613 1090.15197 515.4597796 749.2429735 1058.963074 0.941924796 0.95586065 0.817220717 0.782790081 0.857957625 0.985793215 1.029452298 0.486758974 0.707525118 1 10.04843657 -1.509312409 0.20912486 0.996117938 5.01E-34 0.012018307 0.157246192 46.06058384 0.65096585 0.111634794 14.70068458 0.03095192 1.509312409 -0.996117938 IMNTFSVVPSPK ddPTM_HeLa_Curcumin_4h_R1 3 IMNTFSVVPSPK 12 0 Q5JP53;P07437;Q5ST81;P04350;M0QYM7;M0R042;M0R2D3;P68371;A0A0B4J269;Q13509;Q13509-2;G3V2A3 Q5JP53;P04350;P68371;A0A0B4J269 TUBB;TUBB4A;TUBB4B;TUBB3 Tubulin beta chain;Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-3 chain 0 0 ;; ;; 157.68 1.78E-05 7339600 5705 3517.04 4822.13 4509.97 4883.63 7473.1 5964.1 5535 5242.4 4460.6 FALSE FALSE TRUE 5253.44323 3821.037266 5000.84238 4491.308939 4825.395902 5923.094821 6131.436594 7222.59602 4667.321836 4615.605518 1.138191557 0.827851785 1.083463992 0.973070363 1.045452408 1.283275791 1.328414348 1.564820909 1.011204666 1 12.17230421 -4.717650028 1.256313323 1.040378658 1.586988677 0.808165504 0.088474772 0.259070355 0.572000934 0.014196403 0.147421919 1.92E-05 4.717650028 0.546610019 IMNVIGEPIDER ddPTM_HeLa_Curcumin_4h_R1 2 IMNVIGEPIDER 12 0 P06576;H0YH81;F8W079 P06576 ATP5B "ATP synthase subunit beta, mitochondrial;ATP synthase subunit beta" 0 0 ; ; 115.29 0.0016209 2642750 974.85 788.52 873.75 1194.31 1208.92 1273.88 1027.4 1252.76 990.81 870.79 FALSE FALSE TRUE 897.6895938 856.6761552 906.1319436 1189.368262 1194.504419 1009.662928 1056.226079 1634.720757 882.1206219 901.0498877 0.996270691 0.950753301 1.005640149 1.319980478 1.32568067 1.120540541 1.172217092 1.81424001 0.978991989 1 9.815463175 -1 0.45868172 1.002473515 17.43264219 0.711482457 0.135338765 32.75920234 0.347031466 0.029155945 510.9401113 0.1 1 16.43016867 IMRSYNCTPVS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 IMRSYNCTPVSSPR 14 1 Q8N122-3;Q8N122;Q8N122-2 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 0 IMRSYNCT(0.001)PVS(0.997)S(0.002)PR 80.916 0.0091973 0 1039 976.16 1269.2 923.92 835.72 1007.9 1188 1248 980.98 1467 TRUE FALSE FALSE 956.7620537 1060.534921 1316.237669 920.0970638 825.7545848 798.8501786 1221.332083 1628.509455 873.3689483 1517.978141 0.630287109 0.698649666 0.867099224 0.606133276 0.543983186 0.526259343 0.804578175 1.072814826 0.575350148 1 10.5679353 -9.36536949 0.991288228 1.007120538 0.704199141 0 0.203748168 0.560197064 0.947746066 0.124347078 0.029351239 4.31E-10 9.36536949 -0.302921398 IMS(ph)QDAMMITDEVK ddPTM_HeLa_Curcumin_4h_R1 1 IMSQDAMMITDEVK 14 0 G5E9W6;Q5T5S1-3;Q5T5S1-4;Q5T5S1-2;Q5T5S1 G5E9W6 CCDC183 Coiled-coil domain-containing protein 183 1 0 IMS(1)QDAMMITDEVK 82.515 0.016804 9751500 1864.9 1492.1 1499.4 1881.8 1593.8 354.68 591.72 395.62 1969.6 1446.6 TRUE FALSE FALSE 1717.291197 1621.070475 1554.969083 1874.01361 1574.794976 281.1153699 608.3220707 516.2427168 1753.539808 1496.869242 1.147255317 1.082974003 1.038814239 1.251955453 1.052059145 0.187802222 0.406396266 0.344881638 1.171471601 1 10.54773249 -5.269206898 24.6930767 1.08272594 0.322363658 0.945417214 0.0872159 76.698901 243827.4925 0.012715341 0.028941197 5.38E-06 5.269206898 -0.760362282 IMS(ph)SPLSK ddPTM_HeLa_Curcumin_4h_R1 2 IMSSPLSK 8 0 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;Q9UNX3;P61254;J3QRC4;E5RHH1;J3KSS0 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 1 0 IMS(0.977)S(0.023)PLSK;IMS(0.499)S(0.499)PLS(0.002)K ; 140.17 0.0030285 104851000 8725.7 7313.3 6422.3 7423.5 7069.2 12638.2 7724.2 5412.9 8486.8 6426.1 TRUE FALSE FALSE 8035.051638 7945.429065 6660.316088 7392.783524 6984.904407 10016.89486 7940.920263 7063.268292 7555.819273 6649.406497 1.208386289 1.194908007 1.001640686 1.111795997 1.050455317 1.506434426 1.194229931 1.062240411 1.136314839 1 12.69900986 -9.388955837 0.864376036 0.987960022 1.171718209 0.035822733 0.13819803 0.998486527 1.18972549 0.127658094 0.025361437 4.08E-10 9.388955837 0.183758187 IMS(ph)Y(ph)ICSQQDT(ph)LS(ph)NK ddPTM_HeLa_Curcumin_4h_R1 1 IMSYICSQQDTLSNK 15 0 J3KMX3;P02771 J3KMX3 AFP Alpha-fetoprotein 4 0 IMS(0.634)Y(0.867)ICS(0.517)QQDT(0.993)LS(0.988)NK 42.059 0.019981 211820000 7860.7 7263.7 6726.3 7720.9 7680.2 7342.1 6437.7 6275.8 7969.9 7424.3 TRUE FALSE FALSE 7238.5173 7891.541862 6975.582595 7688.952962 7588.618631 5819.265697 6618.324536 8189.26253 7095.62191 7682.293872 0.942233846 1.027237697 0.908007779 1.00086681 0.987806345 0.757490639 0.861503692 1.065991833 0.923633231 1 12.90732144 SLPAPVAQRPDS(ph)PGGGLQAPGQK ddPTM_HeLa_Curcumin_4h_R1 1 SLPAPVAQRPDSPGGGLQAPGQK 23 1 Q5JVS0-2;Q5JVS0 Q5JVS0-2 HABP4 Intracellular hyaluronan-binding protein 4 1 0 SLPAPVAQRPDS(1)PGGGLQAPGQK 113.63 3.18E-06 112700000 2611.4 2552.5 2343.4 2489.8 2188.3 2402.7 1480.9 470.23 3112.7 2621.6 TRUE FALSE FALSE 2404.704934 2773.126726 2430.248465 2479.497867 2162.205952 1904.352936 1522.450068 613.6009623 2771.244598 2712.700405 0.886461671 1.022275339 0.895877945 0.914033066 0.797067729 0.702013732 0.56123045 0.226195625 1.021581518 1 11.40551401 -4.453827602 0.804141499 0.949597468 2.16E-19 0.951329577 0.052391802 0.300688338 0.166434145 0.008779594 0.238669529 3.52E-05 4.453827602 -0.949597468 down IMSSPLSK ddPTM_HeLa_Curcumin_4h_R1 1 IMSSPLSK 8 0 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;Q9UNX3;P61254;J3QRC4;E5RHH1;J3KSS0 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 0 0 95.909 0.017158 1621800 2205.5 1432.7 2022.9 2102 2001.3 2092.3 1894.9 1936.5 1941.2 1462.7 FALSE FALSE TRUE 2030.932348 1556.536204 2097.870454 2093.302481 1977.435805 1658.333395 1948.065794 2526.929935 1728.255217 1513.528716 1.341852537 1.028415376 1.386079056 1.383060961 1.306506962 1.095673559 1.287101971 1.669561937 1.141871441 1 10.56370033 -12.62147944 0.212327346 3.60E-13 1.365844585 0.279347049 0.163381235 28.83172012 0.504764243 12.26500998 0.147527076 2.39E-13 12.62147944 1.365844585 AVSPPHLDGPPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 AVSPPHLDGPPSPR 14 0 P29590;P29590-5;P29590-4;P29590-9;P29590-3;P29590-8;P29590-11;H3BVD2;P29590-12;H3BT57;P29590-13;H3BRN3;H3BUJ5;P29590-2 P29590;P29590-2 PML Protein PML 1 0 AVSPPHLDGPPS(1)PR;AVSPPHLDGPPS(1)PR;AVSPPHLDGPPS(1)PR ;; 110.34 0.0013798 102970000 14325.7 12015.7 12747.7 13697.5 15349.5 15770.5 8664.5 3010.65 15969.6 12384.9 TRUE FALSE FALSE 13191.80573 13054.28357 13220.14098 13640.82337 15166.46724 12499.52053 8907.602551 3928.583326 14217.77483 12815.27435 1.029381453 1.018650339 1.031592505 1.064419145 1.18346801 0.975361134 0.695077008 0.306554758 1.109439755 1 13.64557674 -4.452913429 2.026034972 1.031195058 0.238521247 0.943310531 0.057936119 0.080216843 0.47049395 0.008277703 0.100746783 3.52E-05 4.452913429 -0.792673811 down INAEK(ac)SSK ddPTM_HeLa_Curcumin_4h_R1 1 INAEKSSK 8 1 Q9C005 Q9C005 DPY30 Protein dpy-30 homolog 0 1 INAEK(1)SSK 134.25 0.0012293 8145900 3911 3964.7 4012.6 3459.8 3828.4 4918.5 3455.3 3307.6 4002.9 3412.7 FALSE TRUE FALSE 3601.440223 4307.391002 4161.310486 3445.484264 3782.74883 3898.347657 3552.246419 4316.072014 3563.791885 3531.291071 1.019865016 1.219777955 1.178410503 0.97570101 1.071208449 1.103944019 1.005934189 1.222236266 1.009203663 1 11.78598003 -7.486733633 24.30531316 1.008763909 1.10380281 0.261641983 0.077569824 338.2978758 227486.306 0.013115763 0.014617105 3.26E-08 7.486733633 0.095038901 INFDDNAEFR ddPTM_HeLa_Curcumin_4h_R1 1 INFDDNAEFR 10 0 E9PDQ8;Q96I99;Q96I99-2 E9PDQ8 SUCLG2 "Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial" 0 0 153.1 0.0055743 8682800 1205.1 909.47 1004.5 1071.7 1187.9 1997 1264.8 947.84 1452.3 880.75 FALSE FALSE TRUE 1109.715063 988.0805343 1041.727654 1067.265589 1173.735068 1582.799689 1300.286884 1236.832053 1292.986323 911.3559969 1.21765267 1.08418723 1.143052394 1.171074304 1.287899649 1.736752372 1.42676066 1.357133828 1.418750003 1 9.831870904 -5.58298976 3.240476005 1.11084584 1.501793147 0.4833413 0.144918982 0.105849286 2.256141783 0.017762124 0.038762875 2.61E-06 5.58298976 0.390947307 KQS(ph)AGPNSPTGGGGGGGSGGTR ddPTM_HeLa_Curcumin_4h_R1 1 KQSAGPNSPTGGGGGGGSGGTR 22 1 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 0 KQS(0.984)AGPNS(0.012)PT(0.004)GGGGGGGSGGTR 69.081 0.0012271 1369500 204.44 200.45 214.72 150.59 261.66 332.46 118.3 0 235.74 230.12 TRUE FALSE FALSE 188.2583583 217.7760048 222.6777121 149.9668985 258.5398754 263.5040484 121.6191796 0 209.8799118 238.1166529 0.790613995 0.914576961 0.93516228 0.629804328 1.08576982 1.106617472 0.510754616 0 0.881416353 1 7.89552471 -4.452779429 3.136144805 0.906741511 0.00565783 0.816428651 0.135780224 0.088367025 1.511903033 0.019895933 0.151137862 3.53E-05 4.452779429 -0.901083681 down INFVGGNK(ac)LQSTGNK ddPTM_HeLa_Curcumin_4h_R1 2 INFVGGNKLQSTGNK 15 1 Q96KR1 Q96KR1 ZFR Zinc finger RNA-binding protein 0 1 ; INFVGGNK(1)LQSTGNK;INFVGGNK(1)LQSTGNK 231.69 1.28E-36 24373400 5555.5 6547.5 6563.2 5725 5645.2 8148.6 6320.9 4721.9 5191.7 5043.1 FALSE TRUE FALSE 5115.776313 7113.436725 6806.437966 5701.311467 5577.884677 6458.488506 6498.247442 6161.585573 4622.183499 5218.34735 0.980344153 1.363158918 1.304328269 1.092551163 1.068898696 1.237650174 1.245269241 1.180754204 0.885756196 1 12.34937726 -7.289669167 24.44239423 0.990718051 1.208712677 0.628597364 0.089556487 279.1362056 241685.658 0.014921971 0.017064588 5.13E-08 7.289669167 0.217994626 INHEGEVNR ddPTM_HeLa_Curcumin_4h_R1 4 INHEGEVNR 9 0 E9PC52;Q16576;Q16576-2;Q5JP01;Q09028-3;Q09028;Q09028-2;Q09028-4 E9PC52;Q09028-3 RBBP7;RBBP4 Histone-binding protein RBBP7;Histone-binding protein RBBP4 0 0 ;;; ;;; 172.59 0.00038965 36384800 11881.9 12402.9 10903 9911.66 9725.9 14441.6 9886.2 9544.41 10795.2 12374.1 FALSE FALSE TRUE 10941.43508 13474.95141 11307.07477 9870.648177 9609.924995 11446.24937 10163.58016 12454.45667 9610.993568 12804.09905 0.854525963 1.052393562 0.883082419 0.770897518 0.75053504 0.893951954 0.793775503 0.972692934 0.750618496 1 13.64431812 -6.524678381 24.98801429 0.939860097 0.831890058 0.103578708 0.097387609 58.72009881 815325.7915 0.013151866 0.018674705 2.99E-07 6.524678381 -0.107970039 INHTVILDDPFDDPPDLLIPDRS(ph)PEPTR ddPTM_HeLa_Curcumin_4h_R1 6 INHTVILDDPFDDPPDLLIPDRSPEPTR 28 1 Q8WUA2 Q8WUA2 PPIL4 Peptidyl-prolyl cis-trans isomerase-like 4 1 0 INHT(0.001)VILDDPFDDPPDLLIPDRS(0.853)PEPT(0.146)R;INHTVILDDPFDDPPDLLIPDRS(0.768)PEPT(0.232)R;INHTVILDDPFDDPPDLLIPDRS(0.718)PEPT(0.282)R;INHT(0.002)VILDDPFDDPPDLLIPDRS(0.883)PEPT(0.116)R;INHTVILDDPFDDPPDLLIPDRS(0.973)PEPT(0.027)R;INHTVILDDPFDDPPDLLIPDRS(0.667)PEPT(0.333)R ;;;;; 85.191 2.85E-06 68337200 3599.45 3274.96 2908.79 3505.61 3468.65 3004.73 2568.77 2869.81 3723.22 3058.04 TRUE FALSE FALSE 3314.549734 3558.032949 3016.592316 3491.104715 3427.288614 2381.515128 2640.842773 3744.801858 3314.792081 3164.306662 1.047480566 1.124427348 0.953318574 1.103276353 1.08310887 0.752618308 0.834572326 1.183450992 1.047557154 1 11.62767371 -5.323802396 24.99999643 1.035155123 0.914646065 0.20098282 0.113167766 253.8855623 101776.8152 0.015266191 0.034136245 4.74E-06 5.323802396 -0.120509058 INHTVILDDPFDDPPDLLIPDRS(ph)PEPTREQLDSGR ddPTM_HeLa_Curcumin_4h_R1 3 INHTVILDDPFDDPPDLLIPDRSPEPTREQLDSGR 35 2 Q8WUA2 Q8WUA2 PPIL4 Peptidyl-prolyl cis-trans isomerase-like 4 1 0 INHTVILDDPFDDPPDLLIPDRS(0.777)PEPT(0.162)REQLDS(0.06)GR;INHTVILDDPFDDPPDLLIPDRS(0.984)PEPT(0.014)REQLDS(0.002)GR;INHTVILDDPFDDPPDLLIPDRS(0.829)PEPT(0.139)REQLDS(0.032)GR ;; 84.299 1.71E-08 90593800 2753.14 2238.42 2269.89 2710.02 2213.76 2881.45 2161.58 2512.73 3087.06 2608.23 TRUE FALSE FALSE 2535.226064 2431.899051 2354.01412 2698.806655 2187.362358 2283.804789 2222.228117 3278.84981 2748.417241 2698.865798 0.939367221 0.901081874 0.872223481 0.999978086 0.810474666 0.846209097 0.823393338 1.214899167 1.018360099 1 11.39813752 -8.380805728 0.800997842 0.993992194 0.914555807 0.07180606 0.111574402 1.123921515 1.519422815 0.042526052 0.023589853 4.16E-09 8.380805728 -0.079436387 INLIAPPR ddPTM_HeLa_Curcumin_4h_R1 2 INLIAPPR 8 0 P05198;H0YJS4;G3V4T5 P05198 EIF2S1 Eukaryotic translation initiation factor 2 subunit 1 0 0 ; ; 107.59 0.0078385 3639000 4237.7 3802.8 4566.6 4099.4 4006.4 3720.7 3527.3 3608.7 3942.2 3679.8 FALSE FALSE TRUE 3902.281573 4131.497087 4735.842213 4082.437769 3958.626297 2948.984879 3626.266545 4708.976018 3509.750523 3807.672776 1.024846882 1.085045205 1.243762921 1.072160873 1.039644562 0.77448485 0.952357715 1.236707116 0.921757391 1 11.89469379 -4.24980277 23.80744649 1.019411845 1.236707372 0.252865113 0.115004876 1026.942361 2100953 0.015861062 0.321253251 5.63E-05 4.24980277 0.217295526 INLVILGK ddPTM_HeLa_Curcumin_4h_R1 1 INLVILGK 8 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 0 0 101.64 0.0072594 0 191.51 135.92 56.829 244.7 206.08 193.48 66.739 183.31 177.4 177.54 FALSE FALSE TRUE 176.3517814 147.6683192 58.93513273 243.6874962 203.6226306 153.350067 68.61151672 239.2003751 157.9396638 183.7095018 0.959949157 0.80381427 0.320806121 1.32648281 1.108394659 0.834742164 0.373478323 1.302057721 0.859725068 1 7.521282437 -7.394397707 5.23811568 0.982575826 0.853189774 0.004575153 0.319759545 0.712874886 27.32119569 0.053142074 0.060352897 4.03E-08 7.394397707 -0.129386052 INLWHLEITDR ddPTM_HeLa_Curcumin_4h_R1 2 INLWHLEITDR 11 0 A0A590UJJ1;A0A590UJY3;P63151;Q66LE6;P63151-2 A0A590UJJ1 PPP2R2A;PPP2R2D Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform;Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform 0 0 ; ; 122.18 0.0031256 13623500 7844.4 6230.2 7276.9 6084.8 6877.1 9364 7845.5 8209.1 6136.6 6585.6 FALSE FALSE TRUE 7223.507463 6768.710727 7546.588315 6059.62271 6795.095074 7421.800846 8065.623615 10712.0168 5463.430333 6814.44911 1.060028088 0.993288029 1.107439236 0.889231486 0.997159853 1.089127048 1.183606112 1.571956387 0.80174204 1 12.73438132 -4.141025572 1.511914902 1.020732847 1.909375394 0.798770363 0.088299671 0.317371651 0.529572282 0.007905295 0.455585303 7.23E-05 4.141025572 0.888642546 INNFSADIK(ac)DSK ddPTM_HeLa_Curcumin_4h_R1 1 INNFSADIKDSK 12 1 P13797;P13797-3 P13797 PLS3 Plastin-3 0 1 INNFSADIK(1)DSK 132.79 0.00035725 1565700 487.41 831.07 619.51 577.82 1236.7 1361.9 1074.9 1326.8 1371.9 731.6 FALSE TRUE FALSE 448.8309842 902.9039876 642.4695856 575.4291339 1221.95316 1079.426588 1105.058801 1731.335212 1221.406002 757.0230455 0.592889459 1.192703436 0.848679032 0.760121026 1.614155827 1.425883392 1.459742616 2.287031052 1.613433051 1 9.56419341 -3.560906321 0.479912512 0.815026266 4.336013884 0.483028108 0.34519772 2.909910158 0.278161309 0.054529727 6.722273556 0.000274849 3.560906321 3.520987618 INPDEREEMK(ac)VSAK ddPTM_HeLa_Curcumin_4h_R1 2 INPDEREEMKVSAK 14 2 P48507-2;P48507 P48507-2 GCLM Glutamate--cysteine ligase regulatory subunit 0 1 ; INPDEREEMK(1)VSAK;INPDEREEMK(1)VSAK 118.51 0.00015302 4535200 2950.7 2240 2398.2 2324.07 2298.6 3072.1 2352.7 2417.5 3116.6 2508.4 FALSE TRUE FALSE 2717.148981 2433.615619 2487.079402 2314.453614 2271.190696 2434.91183 2418.71043 3154.584621 2774.716777 2595.566713 1.046842282 0.937604727 0.958202842 0.891694905 0.875026901 0.938104121 0.93186217 1.215374124 1.06902156 1 11.34183385 -7.257720168 24.55107626 1.022119966 0.955326935 0.11143835 0.090879859 428.2576169 2826992.248 0.014652846 0.017566148 5.52E-08 7.257720168 -0.066793032 INPPSSGGTSS(ph)SPIK ddPTM_HeLa_Curcumin_4h_R1 2 INPPSSGGTSSSPIK 15 0 P14859-6;P14859-2;P14859;P14859-3;P14859-5;P14859-4;A0A0C4DG88;A0A0A0MT46 P14859-6 POU2F1 "POU domain, class 2, transcription factor 1;POU domain protein" 1 0 INPPS(0.001)S(0.001)GGT(0.189)S(0.189)S(0.31)S(0.31)PIK;INPPSSGGT(0.09)S(0.09)S(0.61)S(0.211)PIK ; 125.28 0.00092598 115944000 7945.6 6865.7 7551.9 7398.9 8066.4 8363.6 7348.7 5006.75 7213.3 7002.6 TRUE FALSE FALSE 7316.697376 7459.140515 7831.780057 7368.285312 7970.213448 6628.895083 7554.884744 6533.285027 6422.019037 7245.939829 1.00976513 1.029423469 1.080850827 1.016884695 1.099955787 0.91484269 1.042636969 0.901647706 0.886292074 1 12.82295711 -4.252347717 24.30375454 1.014525219 0.901647618 0.204106513 0.062713039 709.3190109 1896084.983 0.006149621 0.100188716 5.59E-05 4.252347717 -0.1128776 INPYMS(ph)SPCHIEMILTEK ddPTM_HeLa_Curcumin_4h_R1 3 INPYMSSPCHIEMILTEK 18 0 A0A087WXM6;J3QQT2;J3KRX5;A0A0A6YYL6;P18621;P18621-3;J3QLC8;A0A0A0MRF8;P18621-2 A0A087WXM6 RPL17;RPL17-C18orf32 60S ribosomal protein L17 1 0 INPY(0.008)MS(0.61)S(0.382)PCHIEMILTEK;INPY(0.071)MS(0.527)S(0.401)PCHIEMILTEK;INPY(0.033)MS(0.484)S(0.484)PCHIEMILTEK ;; 95.591 0.00096101 170188000 9006.3 7464.7 8219.4 7777.3 9385.8 11914.4 8217.2 7733.5 8789.5 7308 TRUE FALSE FALSE 8293.441852 8109.915406 8524.018195 7745.119593 9273.880465 9443.219137 8447.752517 10091.40855 7825.31384 7561.952456 1.096732874 1.072463157 1.127224516 1.024222202 1.226387037 1.248780549 1.117139068 1.334497751 1.034827167 1 12.88454306 -1 0.168172583 0.990282779 2.141674707 0.643920682 0.061703753 27.27522136 0.284620952 0.091945128 7.9201761 0.1 1 1.151391928 AAGS(ph)PSPLPAPDPAPK ddPTM_HeLa_Curcumin_4h_R1 2 AAGSPSPLPAPDPAPK 16 0 J3KRF7;J3KRY8;Q9BZE9-3;Q9BZE9;Q9BZE9-2 J3KRF7 ASPSCR1 Tether containing UBX domain for GLUT4 1 0 AAGS(0.691)PS(0.309)PLPAPDPAPK;AAGS(0.929)PS(0.071)PLPAPDPAPK ; 130.95 0.00046012 33918400 6989.2 5697 5837.7 7079.2 6403.8 8163.3 7653.6 12968.6 7120.8 7268 TRUE FALSE FALSE 6435.997445 6189.423295 6054.050297 7049.908146 6327.438867 6470.139561 7868.339417 16922.66644 6339.666055 7520.562459 0.855786715 0.823000052 0.80499967 0.937417671 0.841351814 0.860326551 1.046243477 2.250186277 0.842977648 1 12.87662485 -4.259809953 3.662643421 0.904489574 2.400804747 0.977270089 0.062555912 0.034631201 0.847477742 0.010822331 0.141052578 5.50E-05 4.259809953 1.496315173 up INSITVDNCK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 INSITVDNCKK 11 1 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 0 1 ; INSITVDNCK(1)K;INSITVDNCK(1)K 205.56 6.01E-23 7772100 4208.5 4422.1 4606.5 3706.3 7761.4 8507.8 6492.2 6248.2 7462.3 4159.6 FALSE TRUE FALSE 3875.392784 4804.32662 4777.220942 3690.964313 7668.850374 6743.186377 6674.353659 8153.247417 6643.70436 4304.14579 0.90038604 1.116209082 1.109911507 0.85753701 1.781735737 1.566672391 1.550680201 1.894277707 1.543559322 1 12.07151123 -5.760863338 24.99998966 0.97258419 1.678389417 0.633232043 0.216974294 3.446731088 149574.1649 0.017493228 0.033372898 1.73E-06 5.760863338 0.705805227 INSS(ph)PNVNTTASGVEDLNIIQVTIPDDDNER ddPTM_HeLa_Curcumin_4h_R1 2 INSSPNVNTTASGVEDLNIIQVTIPDDDNER 31 0 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 0 INS(0.411)S(0.588)PNVNTTASGVEDLNIIQVTIPDDDNER;INS(0.277)S(0.721)PNVNT(0.003)TASGVEDLNIIQVTIPDDDNER ; 130.89 9.94E-13 15876400 2429.84 1775.04 2066.29 2005.44 2014.77 2590.84 1784.22 983 2283.61 2000.41 TRUE FALSE FALSE 2237.5156 1928.466548 2142.868525 1997.142021 1990.745184 2053.470579 1834.280411 1282.712175 2033.103696 2069.924099 1.080965047 0.931660513 1.035240146 0.964838287 0.961747914 0.992051148 0.886158296 0.61969044 0.982211714 1 11.01536215 -3.804936743 1.019927152 1.023430938 1.61E-19 0.85998776 0.044806937 1.074230168 0.460965857 0.007490436 1.498762649 0.000156698 3.804936743 -1.023430938 INSSGES(ph)GDESDEFLQSR ddPTM_HeLa_Curcumin_4h_R1 1 INSSGESGDESDEFLQSR 18 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 0 INSS(0.001)GES(0.826)GDES(0.173)DEFLQSR 254.8 5.52E-42 13504000 1204.8 994.33 1139 1247.7 1099.7 1527.2 623.02 539.48 1303.5 1160.6 TRUE FALSE FALSE 1109.438809 1080.275455 1181.212342 1242.537348 1086.586796 1210.441505 640.5002644 703.9649685 1160.509311 1200.930764 0.923815795 0.899531836 0.983580717 1.034645282 0.904787211 1.007919475 0.533336545 0.586182809 0.966341563 1 10.22993726 -4.759868136 24.99999999 0.963261134 0.559759534 0.93160679 0.043926263 7.00740494 111483.4344 0.00648159 0.021926093 1.74E-05 4.759868136 -0.4035016 INSSGESGDES(ph)DEFLQSR ddPTM_HeLa_Curcumin_4h_R1 2 INSSGESGDESDEFLQSR 18 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 0 INSSGES(0.002)GDES(0.998)DEFLQSR;INSSGES(0.001)GDES(0.997)DEFLQS(0.002)R ; 174.72 3.37E-06 15170000 2015.38 1486.02 1562.41 2054.36 1739.42 2261.13 1012.58 1192.22 1866.34 1431.23 TRUE FALSE FALSE 1855.860546 1614.464947 1620.314289 2045.859603 1718.678553 1792.14615 1040.99027 1555.72239 1661.607171 1480.965136 1.253142631 1.090143791 1.094093473 1.381436708 1.1605125 1.210120418 0.702913421 1.05047874 1.121975887 1 10.53232196 -4.776319969 24.99797214 1.144494198 0.876696023 0.446656358 0.126408239 160.6641764 269901.831 0.019405476 0.058558773 1.67E-05 4.776319969 -0.267798175 INVELSTK(ac)GQK ddPTM_HeLa_Curcumin_4h_R1 2 INVELSTKGQK 11 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 0 1 ; INVELSTK(1)GQK;INVELSTK(1)GQK 172.17 5.02E-09 11793000 9672.1 7779.8 8689.2 10350.2 9486.7 12724.6 11147.7 11791.6 9808.7 8427.6 FALSE TRUE FALSE 8906.543079 8452.251246 9011.229396 10307.37361 9373.577298 10085.37452 11460.47446 15386.80456 8732.71015 8720.458473 1.021338856 0.969243908 1.033343536 1.181976114 1.07489501 1.156518841 1.314205497 1.764449037 1.001404935 1 13.09018827 -1 0.641780662 1.012994093 64.17732145 0.955660042 0.047952897 26.12437325 0.161055497 0.008262321 2345.206587 0.1 1 63.16432736 INVYYNEATGGK ddPTM_HeLa_Curcumin_4h_R1 3 INVYYNEATGGK 12 0 P68371 P68371 TUBB4B Tubulin beta-4B chain 0 0 ;; ;; 224.42 3.22E-29 30341000 8139.3 6245.3 6296.6 7154.1 6327.3 8164.7 6417.7 5685 7000.2 6306.5 FALSE FALSE TRUE 7495.065816 6785.115903 6529.957535 7124.49823 6251.85108 6471.249185 6597.76339 7418.330329 6232.295574 6525.650406 1.148554604 1.039760864 1.000660031 1.091768297 0.9580426 0.991663479 1.011050697 1.136795548 0.955045886 1 12.67190599 -7.016886703 24.6430548 1.071414308 1.027620325 0 0.069109909 1269.916243 1853210.612 0.011740754 0.014561695 9.62E-08 7.016886703 -0.043793983 INVYYNESSSQK ddPTM_HeLa_Curcumin_4h_R1 1 INVYYNESSSQK 12 0 Q9BUF5;K7ESQ3;K7EQT3;K7EJ64;K7ERA8;K7EJZ4;K7EL29;K7EN98;K7EPE5 Q9BUF5 TUBB6 Tubulin beta-6 chain 0 0 140.78 0.00012006 1522500 1126 890.5 1011.6 729.28 952.02 1130 805.87 792.82 997.36 1037.1 FALSE FALSE TRUE 1036.875912 967.470852 1049.090786 726.2624326 940.6677833 895.6252623 828.4805433 1034.547168 887.9521033 1073.139148 0.966208263 0.901533463 0.97759064 0.676764457 0.876557141 0.834584466 0.772015954 0.964038233 0.827434266 1 10.06762144 -6.337173445 24.99067596 0.975696845 0.825279521 0.223964389 0.086619839 71.83988346 23705.31687 0.010461924 0.015980854 4.60E-07 6.337173445 -0.150417324 INYTEGR ddPTM_HeLa_Curcumin_4h_R1 2 INYTEGR 7 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YX90;A0A0J9YYH3;K7EPY4;K7EP41;K7ERC6;K7ERK8;A0A2R8YF08;K7ELR7 P06744-2 GPI Glucose-6-phosphate isomerase 0 0 ; ; 148.04 0.0014935 18647600 9344.8 6911 8914.2 7818.4 7481.6 9849.9 8364.9 7446.6 9708.1 7969 FALSE FALSE TRUE 8605.149219 7508.356045 9244.568094 7786.049532 7392.386806 7806.919709 8599.596581 9717.03406 8643.145718 8245.922157 1.043564207 0.910553835 1.121107854 0.944230298 0.896490006 0.946761267 1.042890827 1.178404777 1.048172121 1 13.00946513 -4.310289234 3.469801498 1.001887104 1.191571403 0.415158401 0.066434638 0.201800061 4.121648288 0.00908064 0.092182312 4.89E-05 4.310289234 0.189684299 IPCDS(ph)PQSDPVDT(ph)PTSTK ddPTM_HeLa_Curcumin_4h_R1 2 IPCDSPQSDPVDTPTSTK 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 2 0 IPCDS(0.936)PQS(0.065)DPVDT(0.87)PT(0.101)S(0.026)T(0.002)K;IPCDS(0.958)PQS(0.042)DPVDT(0.93)PT(0.065)S(0.005)TK ; 174.7 1.53E-05 16851000 6429.9 4518.3 5816 7586.9 6878.7 12024.3 9461.3 2521.94 8655.2 5171.9 TRUE FALSE FALSE 5920.96663 4908.841719 6031.546076 7555.507418 6796.675995 9530.324638 9726.758614 3290.867896 7705.746214 5351.62314 1.106387067 0.917262219 1.127049854 1.411816045 1.270021415 1.780828804 1.817534299 0.614928931 1.439889546 1 12.38576081 -6.319212758 3.270508375 1.04072693 1.423809271 0.106975655 0.337930666 0.261645445 5.589806969 0.04603628 0.074035202 4.79E-07 6.319212758 0.383082341 IPCKS(ph)PPPELTDTATSTK ddPTM_HeLa_Curcumin_4h_R1 1 IPCKSPPPELTDTATSTK 18 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 IPCKS(1)PPPELTDTATSTK 86.832 0.0017418 35956000 916.42 713.36 993.85 1324.6 1213.9 1870.2 1982.4 714.43 1322.7 597.56 TRUE FALSE FALSE 843.88439 775.0196597 1030.682955 1319.119156 1199.425035 1482.299439 2038.020809 932.2564182 1177.603119 618.3251655 1.364790626 1.253417624 1.666894723 2.133374525 1.93979657 2.397281432 3.296034065 1.507712236 1.904504595 1 9.272221914 -6.301753774 0.778592153 1.132478155 2.482335123 0.38850867 0.491233707 0.292586236 0.349641489 0.080107434 0.185462536 4.99E-07 6.301753774 1.349856968 IPCKS(ph)PPPELTDTATSTKR ddPTM_HeLa_Curcumin_4h_R1 1 IPCKSPPPELTDTATSTKR 19 2 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 IPCKS(0.999)PPPELT(0.001)DTATSTKR 46.154 0.016033 31848000 2420.6 1803.3 2083.8 2999.5 2553 5369.3 4449.3 1468.4 3882 2158.8 TRUE FALSE FALSE 2229.006956 1959.169217 2161.027461 2987.088864 2522.557142 4255.646656 4574.135383 1916.1084 3456.154312 2233.818139 0.997846206 0.87704956 0.967414233 1.337212198 1.129258062 1.905099874 2.047675817 0.857772782 1.547195921 1 11.12529602 -5.682894824 1.740172644 0.992225137 1.624567815 0.212721677 0.362817958 0.240147646 1.467540785 0.045006906 0.109670395 2.08E-06 5.682894824 0.632342678 IPCKS(ph)SPELEDTATSSK ddPTM_HeLa_Curcumin_4h_R1 1 IPCKSSPELEDTATSSK 17 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 IPCKS(0.5)S(0.5)PELEDTATSSK 67.994 0.0095342 60900000 1683.1 1279.8 1145.1 2299.1 1389.4 3236.8 3779 1095.4 2319.4 1672.3 TRUE FALSE FALSE 1549.880859 1390.420209 1187.538413 2289.586933 1372.832312 2565.451194 3885.028569 1429.382417 2064.967623 1730.412301 0.89567143 0.803519606 0.686274833 1.323145318 0.793355614 1.482566434 2.245146182 0.826035747 1.193338502 1 10.75690011 -5.176087019 5.404887929 0.937942195 1.606763932 0.324230803 0.366705743 0.151302041 7.302775172 0.044602418 0.116383631 6.67E-06 5.176087019 0.668821738 IPCKSS(ph)PELEDTATSSK ddPTM_HeLa_Curcumin_4h_R1 1 IPCKSSPELEDTATSSK 17 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 IPCKS(0.23)S(0.564)PELEDT(0.17)AT(0.017)S(0.017)S(0.002)K 60.307 0.015033 58125000 2301.8 1277.5 1927.5 2745.4 2325.7 4426 4585 1709.4 3606.6 2205.7 TRUE FALSE FALSE 2119.610101 1387.921408 1998.934846 2734.040262 2297.967546 3507.997709 4713.64276 2230.588191 3210.965003 2282.347911 0.928697194 0.608111235 0.875823899 1.197906879 1.00684367 1.537012693 2.0652604 0.977321722 1.40686921 1 11.15630301 -5.272598948 4.141768188 0.948636743 1.588979886 0.354408894 0.315851208 0.120976211 5.030028414 0.037104022 0.092351499 5.34E-06 5.272598948 0.640343143 IPDPDS(ph)DDVSEVDAR ddPTM_HeLa_Curcumin_4h_R1 2 IPDPDSDDVSEVDAR 15 0 P51532;P51532-4;P51532-3;P51532-2;P51532-5;A0A0A0MT49;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8Y440;A0A2R8Y4C5;A0A2R8Y6N0;A0A2R8YG32;A0A2R8Y7F3;A0A2R8YF80;A0A2R8YF58;A0A2R8Y526;A0A2R8Y7Y7;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8YGP5;A0A2R8Y7R0;A0A2R8Y583 P51532 SMARCA4 Transcription activator BRG1 1 0 IPDPDS(0.985)DDVS(0.015)EVDAR;IPDPDS(0.999)DDVS(0.001)EVDAR ; 154.46 0.00039004 12281900 1246.72 1441.32 1589.93 1030.66 1211.36 1830.25 1476.01 1234.09 1460.9 1368.24 TRUE FALSE FALSE 1148.040796 1565.901278 1648.854204 1026.395402 1196.915323 1450.635519 1517.422868 1610.35836 1300.642925 1415.786238 0.810885687 1.106029453 1.164620873 0.724964952 0.845406807 1.02461479 1.071788118 1.137430437 0.918671823 1 10.46738774 -4.932661181 3.007431493 0.925434035 1.107655901 0.213843955 0.125731604 0.300146474 5.43271832 0.019538487 0.069192811 1.17E-05 4.932661181 0.182221866 IPEISIQDMTAQVTS(ph)PSGK ddPTM_HeLa_Curcumin_4h_R1 2 IPEISIQDMTAQVTSPSGK 19 0 P21333-2;P21333;Q60FE5 P21333-2;Q60FE5 FLNA Filamin-A 1 0 IPEISIQDMTAQVT(0.106)S(0.884)PS(0.01)GK;IPEISIQDMTAQVT(0.033)S(0.648)PS(0.319)GK ; 207.16 1.38E-13 46586000 4510.5 3841.3 4326.7 4549.5 5967 6267.4 5685.6 5664.2 3729.9 3663 TRUE FALSE FALSE 4153.489166 4173.324855 4487.051308 4530.675374 5895.847422 4967.470592 5845.122634 7391.188505 3320.739302 3790.288977 1.095823878 1.10105717 1.183828287 1.195337717 1.555513961 1.310578328 1.542131133 1.950032979 0.876117711 1 11.88809213 -1 0.299456003 1.010480892 8.599861323 0.877269304 0.106165883 10.16168767 0.129996621 0.034458735 41.86153745 0.1 1 7.589380431 TTDLSIQS(ph)PSADLEVQAGQVDVK ddPTM_HeLa_Curcumin_4h_R1 1 TTDLSIQSPSADLEVQAGQVDVK 23 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 T(0.001)T(0.001)DLS(0.024)IQS(0.709)PS(0.265)ADLEVQAGQVDVK 81.765 0.00023181 5517500 1398.4 1502 1495.8 2296.8 2088.7 2088.6 2002.8 8049.8 1990.3 1406.8 TRUE FALSE FALSE 1287.715164 1631.826187 1551.235664 2287.29645 2063.793617 1655.400817 2058.993178 10504.14696 1771.969069 1455.686195 0.884610412 1.121001348 1.065638782 1.571284015 1.417746231 1.137196205 1.414448515 7.215941868 1.217274077 1 10.50748367 -4.259766017 4.557853708 1.059511046 7.620089741 0.986036151 0.214457347 0.017618861 0.942606646 0.03533272 0.369397107 5.50E-05 4.259766017 6.560578695 up IPEPS(ph)PVTR ddPTM_HeLa_Curcumin_4h_R1 1 IPEPSPVTR 9 0 A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YHT2;Q7Z4S6-3;H0YI78 A0A1B0GV47 KIF21A Kinesin-like protein KIF21A 1 0 IPEPS(0.979)PVT(0.021)R 94.465 0.016375 7002700 1055.2 1044.2 1004.2 1249.1 942.84 1133.7 732.95 561.46 1510.7 1232.4 TRUE FALSE FALSE 971.6798066 1134.455995 1041.416535 1243.931555 931.5972488 898.5578406 753.5146044 732.6465694 1344.97999 1275.225808 0.761966861 0.889611854 0.81665265 0.975459834 0.730535128 0.704626455 0.590887198 0.57452301 1.054699474 1 10.31653702 -3.05666642 0.228606336 0.946158952 3.77E-44 0.700822077 0.086987789 10.68976581 0.292032953 0.074615658 3.140716827 0.000877675 3.05666642 -0.946158952 IPESETESTAS(ph)APNS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 IPESETESTASAPNSPR 17 0 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 2 0 IPESETES(0.02)T(0.1)AS(0.89)APNS(0.99)PR 104.16 0.0012235 0 595.4 565.33 787.29 546.09 610.84 832.79 711.99 459.52 723.46 863.01 TRUE FALSE FALSE 548.2734617 614.1946061 816.46766 543.8304243 603.556132 660.0599665 731.9665232 599.6255326 644.098248 892.9995333 0.613968363 0.687788272 0.914297969 0.608992955 0.675875081 0.739149285 0.819671787 0.671473512 0.721275011 1 9.802515611 -9.427687359 1.113810007 1.002730091 0.711845535 0.007992265 0.121570239 0.2857889 0.624647077 0.065451505 0.015833405 3.74E-10 9.427687359 -0.290884556 IPEVPLHDT(ph)PER ddPTM_HeLa_Curcumin_4h_R1 2 IPEVPLHDTPER 12 0 Q96AY2;Q96AY2-2 Q96AY2 EME1 Crossover junction endonuclease EME1 1 0 IPEVPLHDT(1)PER;IPEVPLHDT(1)PER ; 118.55 0.0035286 14960100 2908.9 2362.06 2632.1 2140.33 2739.6 3746.3 2835.2 1576.33 3047.5 2663.7 TRUE FALSE FALSE 2678.657496 2566.225941 2729.647941 2131.473882 2706.932059 2969.27515 2914.748081 2056.94576 2713.196874 2756.263377 0.971843808 0.931052512 0.990343653 0.773320104 0.982102103 1.077282808 1.057499841 0.746280554 0.984375041 1 11.42849804 -7.752844915 1.237557943 0.992361318 0.944263396 0.042639196 0.101509271 1.143743064 3.648675576 0.02297811 0.021728735 1.77E-08 7.752844915 -0.048097922 IPGTPGAGGRLS(ph)PENNQVLTK ddPTM_HeLa_Curcumin_4h_R1 1 IPGTPGAGGRLSPENNQVLTK 21 1 Q16514-2;Q16514 Q16514-2 TAF12 Transcription initiation factor TFIID subunit 12 1 0 IPGTPGAGGRLS(0.997)PENNQVLT(0.002)K 65.278 0.0022743 200440000 1779 1302.1 1430.6 1495 1583 2199.5 1381.8 1057 2130.3 1877 TRUE FALSE FALSE 1638.190273 1414.647722 1483.619294 1488.814086 1564.123759 1743.298907 1420.569589 1379.274434 1896.61142 1942.22561 0.84346034 0.728364261 0.763875879 0.766550538 0.805325473 0.897577963 0.731413272 0.710151502 0.976514474 1 10.92349508 -8.435266718 0.653309869 0.995606257 0.774093265 0.714056285 0.052921422 0.288739263 0.259090842 0.030258555 0.014037025 3.67E-09 8.435266718 -0.221512993 IPMTPTSSFVSPPPPT(ph)ASPHSNR ddPTM_HeLa_Curcumin_4h_R1 2 IPMTPTSSFVSPPPPTASPHSNR 23 0 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 0 IPMTPTSSFVSPPPPT(0.471)AS(0.471)PHS(0.058)NR;IPMTPTSSFVS(0.138)PPPPT(0.695)AS(0.16)PHS(0.007)NR ; 103.57 2.62E-05 93333000 1619.95 1177.44 1462.54 1213.63 1646.37 1498.46 1661.92 1025.95 1510.66 1383.4 TRUE FALSE FALSE 1491.729248 1279.212667 1516.743019 1208.608321 1626.738113 1187.662505 1708.549002 1338.757432 1344.944377 1431.473047 1.042093843 0.893633778 1.05956799 0.844310917 1.136408482 0.829678566 1.193560023 0.935230625 0.939552708 1 10.48328479 IPNIEGMETESGNQEKVMEEES(ph)TEK ddPTM_HeLa_Curcumin_4h_R1 1 IPNIEGMETESGNQEKVMEEESTEK 25 1 Q4G0J3-3 Q4G0J3-3 LARP7 La-related protein 7 1 0 IPNIEGMET(0.018)ES(0.072)GNQEKVMEEES(0.455)T(0.455)EK 40.381 0.018248 8595600 771.77 704.86 568.66 686.39 653.58 905.23 624.7 288.83 817.83 600.59 TRUE FALSE FALSE 710.6835901 765.7849576 589.7350398 683.5499 645.7864854 717.475094 642.2274007 376.8929374 728.1160951 621.4604578 1.143570088 1.232234405 0.948950223 1.099908919 1.039143323 1.154498384 1.033416354 0.606463264 1.171620955 1 9.279518788 -4.266574225 4.273667381 1.077811723 0.572577896 0.758146711 0.08221848 0.077693561 3.274160662 0.011401654 0.118289954 5.41E-05 4.266574225 -0.505233827 IPNS(ph)YEVLFPESPAR ddPTM_HeLa_Curcumin_4h_R1 1 IPNSYEVLFPESPAR 15 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 0 IPNS(0.407)Y(0.282)EVLFPES(0.311)PAR 93.839 0.0060734 4208700 415.54 276.32 417.2 328.27 370.14 473.61 311.21 186.59 301.97 299.51 TRUE FALSE FALSE 382.6495705 300.2038695 432.661799 326.9117057 365.7263222 375.3779473 319.941715 243.480432 268.8446465 309.9179502 1.234680244 0.96865596 1.396052725 1.054833079 1.180074668 1.211217185 1.032343286 0.785628686 0.867470394 1 8.275742507 -4.331787302 3.092865439 1.129517334 0.757704683 0.311954295 0.144648717 0.231936792 3.471856194 0.017441201 0.189445576 4.66E-05 4.331787302 -0.371812651 IPNSYEVLFPES(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 1 IPNSYEVLFPESPAR 15 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 0 IPNSYEVLFPES(1)PAR 149.52 0.0004486 5244900 557.73 637.07 480.62 516.56 572.56 799.55 431.32 400.14 624.57 762.07 TRUE FALSE FALSE 513.585082 692.1354921 498.4322 514.4226116 565.732596 633.7143172 443.4216784 522.140844 556.0562336 788.5518758 0.651301579 0.877729815 0.632085492 0.65236369 0.717432313 0.803643155 0.562324042 0.662151546 0.705161259 1 9.623061857 -9.63919627 0.540302389 1.105169364 0.684482981 0 0.125665401 0.901127308 0.289530676 0.20814437 0.019930039 2.30E-10 9.63919627 -0.420686383 IPNYQLS(ph)PTKLPSINK ddPTM_HeLa_Curcumin_4h_R1 2 IPNYQLSPTKLPSINK 16 1 A0A0C4DG07;O60934 A0A0C4DG07 NBN Nibrin 1 0 IPNY(0.216)QLS(0.782)PT(0.001)KLPSINK;IPNY(0.062)QLS(0.933)PT(0.005)KLPSINK ; 85.231 0.0039503 524700000 7722.6 5769.8 6476.8 6211.9 6472.2 7468.8 6156 4242.6 6929.1 6069.4 TRUE FALSE FALSE 7111.348061 6268.515802 6716.835906 6186.196804 6395.023242 5919.686689 6328.720792 5536.149209 6168.995066 6280.311198 1.132324153 0.998121845 1.069506859 0.985014374 1.018265344 0.942578561 1.007708152 0.88150874 0.98227538 1 12.61662033 -5.287518829 0.71466426 1.059504712 0.914526953 0.318517296 0.05258997 0.837436988 0.614097449 0.010523286 0.074549739 5.16E-06 5.287518829 -0.144977759 IPQGTFSNLENLTLLDLQNNK ddPTM_HeLa_Curcumin_4h_R1 1 IPQGTFSNLENLTLLDLQNNK 21 0 O60938 O60938 KERA Keratocan 0 0 57.41 0.0089847 4141000 3138.7 2989.7 3284.5 2956.1 3403.9 2966.7 2546.5 2627.8 3159.3 2758.2 FALSE FALSE TRUE 2890.268583 3248.116346 3406.226459 2943.868441 3363.310716 2351.372978 2617.947936 3429.004123 2812.732694 2854.047245 1.012691219 1.138073784 1.193472346 1.031471517 1.178435543 0.82387318 0.917275613 1.201453175 0.985524223 1 11.4787935 -4.235393286 23.20130349 1.024026241 1.201453792 0.176854017 0.109206955 4068.971881 3624402.049 0.01506937 1.339226896 5.82E-05 4.235393286 0.177427551 IPS(ph)PLQPEMQGTPDDEPSEPEPSPSTLIYR ddPTM_HeLa_Curcumin_4h_R1 2 IPSPLQPEMQGTPDDEPSEPEPSPSTLIYR 30 0 Q96GY3;K7EMY4 Q96GY3 LIN37 Protein lin-37 homolog 1 0 IPS(0.8)PLQPEMQGT(0.191)PDDEPS(0.009)EPEPSPSTLIYR;IPS(0.902)PLQPEMQGT(0.098)PDDEPSEPEPSPSTLIYR ; 68.677 0.00011067 9320000 766.54 733.96 873.78 793.55 669.55 1087.79 794.86 419.41 816.79 594.92 TRUE FALSE FALSE 705.8675502 797.4002319 906.1630555 790.2665004 661.5660535 862.1700921 817.1616323 547.2861783 727.1901805 615.5934257 1.146645693 1.295335848 1.472015486 1.283747466 1.07468018 1.400551169 1.327437231 0.889038374 1.181283214 1 9.265834014 -7.919564013 1.227413103 1.036401656 1.256986278 0.100794243 0.164696625 0.387590812 1.222011471 0.037860531 0.032936417 1.20E-08 7.919564013 0.220584622 IPSAS(ph)PQTQR ddPTM_HeLa_Curcumin_4h_R1 1 IPSASPQTQR 10 0 Q13233 Q13233 MAP3K1 Mitogen-activated protein kinase kinase kinase 1 1 0 IPSAS(1)PQTQR 113.95 0.0059077 11864000 426.65 395.01 525.89 437.62 543.26 508.87 368.61 479.03 581.98 412.92 TRUE FALSE FALSE 392.8802023 429.1529043 545.379946 435.8092444 536.7819793 403.3246259 378.9522045 625.0840418 518.13825 427.2689393 0.919515008 1.004409319 1.276432467 1.019988125 1.256309387 0.943959621 0.886917278 1.462975621 1.21267474 1 8.739000632 -6.982208532 24.88678474 0.961991555 1.121990184 0.019009314 0.179336183 280.9979769 393059.8627 0.024319189 0.031958402 1.04E-07 6.982208532 0.159998629 AQS(ph)LLSTDR ddPTM_HeLa_Curcumin_4h_R1 1 AQSLLSTDR 9 0 J3QRY4;O00231;O00231-2 J3QRY4 PSMD11 26S proteasome non-ATPase regulatory subunit 11 1 0 AQS(0.995)LLS(0.005)TDR 134.49 0.00014359 0 709.84 675.24 687.62 795.63 813.33 845.67 1065 5830.4 724.81 514.49 TRUE FALSE FALSE 653.655415 733.6047368 713.1038021 792.3378939 803.631571 670.2685093 1094.881034 7608.06212 645.3001564 532.3684892 1.22782514 1.378001801 1.339492882 1.488326056 1.509540078 1.259031147 2.056622539 14.29097002 1.212130638 1 9.056281371 -4.259722881 4.404806681 1.219619836 15.2315843 0.998338911 0.158159361 0.00789034 0.370772298 0.031927514 0.344033349 5.50E-05 4.259722881 14.01196446 up IPSIVSS(ph)PLNSPLDR ddPTM_HeLa_Curcumin_4h_R1 1 IPSIVSSPLNSPLDR 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 0 IPSIVS(0.208)S(0.792)PLNSPLDR 164.7 0.0002487 31623000 591.2 382.46 416.12 391.89 477.61 689.68 534.96 592.71 651.37 400.55 TRUE FALSE FALSE 544.4058962 415.5181382 431.5417733 390.268463 471.9148127 546.6325937 549.9695378 773.4245505 579.9163406 414.4690827 1.313501824 1.002531083 1.041191711 0.941610555 1.13860076 1.318874233 1.326925363 1.866060903 1.399178768 1 8.695120678 -3.727098328 1.038785415 1.117914834 3.29016938 0.707815394 0.141889562 1.950467928 0.764719737 0.021902913 6.138300111 0.000187457 3.727098328 2.172254546 IPSLGWS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 IPSLGWSPSK 10 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 IPSLGWS(0.99)PS(0.01)K;IPS(0.001)LGWS(0.987)PS(0.012)K ; 140.63 0.0014889 321050000 7735.7 6019.8 6467 6383.6 7247.5 8646.8 5989.5 4909.9 7921.8 5938 TRUE FALSE FALSE 7123.411182 6540.124688 6706.672709 6357.186355 7161.078296 6853.35621 6157.54925 6406.905908 7052.798359 6144.345058 1.159344261 1.06441364 1.091519543 1.034640193 1.165474632 1.11539247 1.002148999 1.042732113 1.147851934 1 12.58504352 -4.754278191 24.98940692 1.082831539 1.022440549 0.204336313 0.05328566 270.0789026 942432.4198 0.009059434 0.03248364 1.76E-05 4.754278191 -0.06039099 IPSTENSSQEISVEERT(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 3 IPSTENSSQEISVEERTPTK 20 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 0 IPSTENSSQEISVEERT(0.989)PT(0.011)K;IPSTENSS(0.001)QEIS(0.01)VEERT(0.842)PT(0.147)K;IPST(0.002)ENS(0.005)S(0.016)QEIS(0.058)VEERT(0.66)PT(0.258)K ;; 135.86 8.94E-05 114705000 5543.5 5698.7 5445.5 6272.3 5603.8 5862.6 4399.1 2908.01 6728.7 6138.7 TRUE FALSE FALSE 5104.726126 6191.270235 5647.31502 6246.346885 5536.978345 4646.630675 4522.526906 3794.648862 5990.578444 6352.019368 0.803638312 0.974693224 0.889058218 0.983363954 0.871687888 0.731520231 0.711982544 0.597392521 0.943098265 1 12.6329996 -5.062520963 1.634149427 0.914829257 0.634881806 0.788529226 0.059166537 0.19298937 0.948397909 0.011774567 0.052042005 8.66E-06 5.062520963 -0.279947451 KPEENPASK(ac)FSSASK ddPTM_HeLa_Curcumin_4h_R1 2 KPEENPASKFSSASK 15 2 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 1 ; KPEENPASK(1)FSSASK;KPEENPASK(1)FSSASK 177.58 6.78E-08 19936500 8455.2 7386.5 7515 6970.3 6836.1 11925.8 9359.7 22052.3 8328.8 6260.3 FALSE TRUE FALSE 7785.961998 8024.956146 7793.512511 6941.458745 6754.583972 9452.254649 9622.307992 28775.94475 7415.151478 6477.844959 1.201937071 1.238831154 1.203102661 1.071569139 1.042720845 1.459166545 1.485418075 4.442209552 1.144694188 1 12.66129822 -4.193790897 2.541325195 1.128882289 5.525917599 0.981679028 0.133062868 0.065999851 0.453520457 0.020557909 0.665864835 6.40E-05 4.193790897 4.39703531 up IPVEGPLS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 IPVEGPLSPSR 11 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 0 IPVEGPLS(0.668)PS(0.332)R 91.202 0.016459 10701000 791.02 779.24 722.51 649.54 846.29 716.43 643.04 641.64 607.04 593.83 TRUE FALSE FALSE 728.4099323 846.5940334 749.2868562 646.8523756 836.1985445 567.8343422 661.0819717 837.2730823 540.4492307 614.4655483 1.185436571 1.377772986 1.219412314 1.052707312 1.36085505 0.924110951 1.075864991 1.362603786 0.879543584 1 9.263188314 -8.982123535 0.960782718 1.007775717 1.186690767 0.297273393 0.147326179 0.651542309 1.153437076 0.071958359 0.026571681 1.04E-09 8.982123535 0.17891505 IPVEGPLS(ph)PSRGDFPK ddPTM_HeLa_Curcumin_4h_R1 1 IPVEGPLSPSRGDFPK 16 1 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 0 IPVEGPLS(0.866)PS(0.134)RGDFPK 111.22 0.014667 21592000 1058.5 803.13 833.02 840.94 847.02 1369.4 806.3 828.7 979.15 937.28 TRUE FALSE FALSE 974.7186081 872.5489785 863.892454 837.4604131 836.9198397 1085.371004 828.922608 1081.366815 871.7396947 969.8504102 1.005019535 0.899673774 0.890748145 0.863494415 0.862937037 1.119111764 0.854691197 1.114983098 0.898839332 1 9.921618433 -7.286210504 22.85712954 1.002370348 0.938765418 0 0.098298903 455.8073745 420586.8846 0.014815825 0.016948798 5.17E-08 7.286210504 -0.06360493 IPVEGPLSPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 IPVEGPLSPSR 11 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 0 IPVEGPLS(0.498)PS(0.502)R 98 0.012311 4516300 1799.1 972.82 1220.8 1469 1541 1963.9 1201.2 1076.4 1456.9 1322.9 TRUE FALSE FALSE 1656.699337 1056.906226 1266.043922 1462.921667 1522.624581 1556.565002 1234.902439 1404.589405 1297.081715 1368.870677 1.210267241 0.77210086 0.924882053 1.068706995 1.112321717 1.137116186 0.902132291 1.026093574 0.947556067 1 10.41877044 IPYPGRS(ph)PQDLASTSR ddPTM_HeLa_Curcumin_4h_R1 1 IPYPGRSPQDLASTSR 16 1 C9J6K3;C9JM54;Q9HC52 C9J6K3;Q9HC52 CBX8 Chromobox protein homolog 8 1 0 IPYPGRS(0.997)PQDLAS(0.001)T(0.001)S(0.001)R 67.655 0.012387 8112500 5495.5 4479.9 4446.2 5236.2 4353.5 5007.5 4018.8 3385.5 4653.8 4268.3 TRUE FALSE FALSE 5060.525376 4867.122594 4610.980083 5214.533992 4301.587356 3968.888054 4131.556712 4417.723365 4143.289783 4416.623107 1.145790631 1.10200089 1.044005787 1.18066085 0.973953913 0.898625026 0.935456029 1.000249117 0.938112599 1 12.10872801 -5.562652476 13.1076054 1.07811062 0.942584057 0.404938851 0.069166646 0.798650039 262.4878968 0.009653568 0.019314198 2.74E-06 5.562652476 -0.135526563 IPYQS(ph)PVSSSESAPGTIMNGHGGGR ddPTM_HeLa_Curcumin_4h_R1 1 IPYQSPVSSSESAPGTIMNGHGGGR 25 0 Q5T6F2;H0YDN2 Q5T6F2 UBAP2 Ubiquitin-associated protein 2 1 0 IPY(0.032)QS(0.829)PVS(0.072)S(0.032)S(0.032)ES(0.003)APGTIMNGHGGGR 53.28 0.0067331 18706000 1648.5 1553.2 1350.6 1417.9 1673.3 2053.9 1064.2 788.52 1713.9 1260.7 TRUE FALSE FALSE 1518.019486 1687.451687 1400.654424 1412.033105 1653.34699 1627.897988 1094.058588 1028.936118 1525.889458 1304.509231 1.163670942 1.293552891 1.073702194 1.082424771 1.267409192 1.247900704 0.83867447 0.78875342 1.169703841 1 10.34929144 -4.67940973 7.071964248 1.116923883 0.805441704 0.655991909 0.096712315 0.126130011 9.00996387 0.015759961 0.059752168 2.09E-05 4.67940973 -0.311482179 T(ph)ASGSSVTSLDGTR ddPTM_HeLa_Curcumin_4h_R1 1 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 0 T(0.246)AS(0.246)GS(0.246)S(0.246)VT(0.018)SLDGTR 203.85 1.46E-08 269840000 1852.1 1336.3 1513.5 1225.1 1715.5 1982 1985.9 5149.9 1830.7 1667.3 TRUE FALSE FALSE 1705.504331 1451.803818 1569.591641 1220.030861 1695.043783 1570.910858 2041.619009 6720.080803 1629.87679 1725.238551 0.988561454 0.841509029 0.909782384 0.707166473 0.982498207 0.910547041 1.183383601 3.895160353 0.944725464 1 10.75258014 -4.259711379 4.112553592 0.953403478 4.147197212 0.989774819 0.090373764 0.016920858 0.618065578 0.013880014 0.159690472 5.50E-05 4.259711379 3.193793734 up IQALQQQADEAEDR ddPTM_HeLa_Curcumin_4h_R1 4 IQALQQQADEAEDR 14 0 P67936;A0A2R8Y5V9;A0A2R8YGX3;A0A590UK79;A0A590UJB9 P67936 TPM4 Tropomyosin alpha-4 chain 0 0 ;;; ;;; 194.48 5.65E-23 65198000 4856.16 4233.84 4734.94 4072.45 5314.57 5903.6 4734.73 4835.15 4607.6 4663.31 FALSE FALSE TRUE 4471.789812 4599.794264 4910.421042 4055.599281 5251.197224 4679.126813 4867.573781 6309.364977 4102.157808 4825.359675 0.926726734 0.953254177 1.017627985 0.840476059 1.088249908 0.96969493 1.008748385 1.30754294 0.850124775 1 12.23642077 -4.244097702 3.076132311 0.967764225 1.368493628 0.685348683 0.070731569 0.146395536 1.99422 0.007977689 0.144916834 5.70E-05 4.244097702 0.400729403 IQDPTEDAEAEDT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 IQDPTEDAEAEDTPR 15 0 O96028-5;O96028-3;O96028;H0Y9L4 O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 0 IQDPTEDAEAEDT(1)PR;IQDPTEDAEAEDT(1)PR ; 201.22 2.34E-30 90558000 5454.8 5214.3 4768.9 4611.7 5468.7 5927.9 5844.4 1327.7 4924.3 4464.6 TRUE FALSE FALSE 5023.046824 5665.000858 4945.639629 4592.618007 5403.489324 4698.386719 6008.378135 1732.509618 4384.11661 4619.744518 1.087299699 1.226258473 1.070543968 0.994128136 1.169651115 1.017023063 1.300586669 0.37502282 0.948995468 1 12.17359735 -4.249657795 24.9405226 1.073059559 0.375022387 0.799465159 0.107180892 546.2993251 1156443.9 0.013515092 0.297379432 5.63E-05 4.249657795 -0.698037172 IQDPTEDAEAEDT(ph)PRKR ddPTM_HeLa_Curcumin_4h_R1 2 IQDPTEDAEAEDTPRKR 17 2 O96028-5;O96028-3;O96028;H0Y9L4 O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 0 IQDPTEDAEAEDT(1)PRKR;IQDPTEDAEAEDT(1)PRKR ; 74.726 0.0062096 52956000 7897.3 6107.1 5684.3 7468.6 4878.6 8628.8 7241.6 2203.31 10118.7 7205.6 TRUE FALSE FALSE 7272.220372 6634.970511 5894.965158 7437.696912 4820.425881 6839.089613 7444.779806 2875.089076 9008.703926 7455.994064 0.975352221 0.889884093 0.790634369 0.997545981 0.646516861 0.917260603 0.998495941 0.385607747 1.208249879 1 12.864185 -3.100440384 0.320186123 0.993150248 1.17E-25 0.40590316 0.166655343 11.36365442 0.469781177 0.051449538 5.102836337 0.000793523 3.100440384 -0.993150248 IQEAGTEVVK ddPTM_HeLa_Curcumin_4h_R1 2 IQEAGTEVVK 10 0 P40926;P40926-2;G3XAL0 P40926 MDH2 "Malate dehydrogenase, mitochondrial;Malate dehydrogenase" 0 0 ; ; 141.91 2.03E-05 13343400 5734.9 4902.2 5352.4 6283 5790 7697.6 5745.4 5814.1 6406.6 5338.6 FALSE FALSE TRUE 5280.976614 5325.924324 5550.764652 6257.002611 5720.958032 6101.03099 5906.600461 7586.792325 5703.812009 5524.115953 0.955985837 0.964122471 1.004824066 1.132670397 1.035633227 1.104435722 1.069239044 1.373394836 1.032529378 1 12.43152789 -1 0.527609078 0.983753476 14.37092436 0.769421224 0.055384208 34.39668182 0.306595073 0.01019898 519.690669 0.1 1 13.38717088 IQEAGTEVVK(ac)AK ddPTM_HeLa_Curcumin_4h_R1 2 IQEAGTEVVKAK 12 1 P40926;P40926-2;G3XAL0 P40926 MDH2 "Malate dehydrogenase, mitochondrial;Malate dehydrogenase" 0 1 ; IQEAGTEVVK(1)AK;IQEAGTEVVK(1)AK 213.63 6.06E-22 11013500 3572.1 3231.4 3181.1 3225 3190.3 5062.4 3086.9 3126.5 3551 3163.4 FALSE TRUE FALSE 3289.364516 3510.707817 3298.994364 3211.655805 3152.257756 4012.401175 3173.510106 4079.755457 3161.464184 3273.327915 1.004899173 1.072519439 1.007841087 0.981159202 0.963013129 1.225786502 0.969505711 1.246363201 0.965825688 1 11.67654242 -1 0.624345763 1.006174637 16.07028373 0.412103275 0.077342569 125.0638901 0.820290564 0.011848872 2594.298906 0.1 1 15.06410909 IQEQES(ph)S(ph)GEEDSDLSPEEREK ddPTM_HeLa_Curcumin_4h_R1 1 IQEQESSGEEDSDLSPEEREK 21 1 E7EMN6;Q6NXS1;P41236 E7EMN6 PPP1R2;PPP1R2P3 Protein phosphatase inhibitor 2-like protein 3;Protein phosphatase inhibitor 2 2 0 IQEQES(0.82)S(0.834)GEEDS(0.27)DLS(0.076)PEEREK 62.617 0.0062543 29385000 2736.2 1844.5 2102.9 2583.6 1391.1 3043.3 2045.1 1817.5 3235 2548.8 TRUE FALSE FALSE 2519.626883 2003.930361 2180.835324 2572.909748 1374.512041 2412.085275 2102.480002 2371.647383 2880.128594 2637.37061 0.955355638 0.759821298 0.826897561 0.975558664 0.521167573 0.914579569 0.797187924 0.899246914 1.092045457 1 11.3648846 -7.36973543 4.962325126 0.980584991 0.812519651 0.361817763 0.120700445 0.19119049 7.170266573 0.018655575 0.021223256 4.27E-08 7.36973543 -0.16806534 IQEQES(ph)SGEEDS(ph)DLSPEER ddPTM_HeLa_Curcumin_4h_R1 2 IQEQESSGEEDSDLSPEER 19 0 E7EMN6;Q6NXS1;P41236 E7EMN6 PPP1R2;PPP1R2P3 Protein phosphatase inhibitor 2-like protein 3;Protein phosphatase inhibitor 2 2 0 IQEQES(0.72)S(0.305)GEEDS(0.966)DLS(0.009)PEER;IQEQES(0.932)S(0.202)GEEDS(0.865)DLSPEER ; 133.92 0.00042787 98235000 4099.2 2973.6 3994.2 3892.7 4295.8 4172 3902.1 2979.1 3803.5 3531.7 TRUE FALSE FALSE 3774.743995 3230.624734 4142.228566 3876.593039 4244.575391 3306.680172 4011.582424 3887.413876 3386.265566 3654.426312 1.032923822 0.884030613 1.13348258 1.060793872 1.161488843 0.904842481 1.097732471 1.063754894 0.926620289 1 11.83542923 -6.707722405 24.99998019 1.00611629 1.067779073 0.247020654 0.079113698 138.9857974 64683.65346 0.011172168 0.015799826 1.96E-07 6.707722405 0.061662783 IQEQES(ph)SGEEDSDLSPEER ddPTM_HeLa_Curcumin_4h_R1 1 IQEQESSGEEDSDLSPEER 19 0 E7EMN6;Q6NXS1;P41236 E7EMN6 PPP1R2;PPP1R2P3 Protein phosphatase inhibitor 2-like protein 3;Protein phosphatase inhibitor 2 1 0 IQEQES(0.5)S(0.5)GEEDSDLSPEER 303.34 2.36E-98 26472000 1332.2 936.39 1031.8 841.52 1044 1054 737.54 964.33 1017.7 775.9 TRUE FALSE FALSE 1226.754964 1017.327379 1070.039416 838.0380132 1031.550982 835.388519 758.2333874 1258.349778 906.0608562 802.8624672 1.527976477 1.267125343 1.332780469 1.043812667 1.284841457 1.040512607 0.944412547 1.567329187 1.128538066 1 9.649009061 -6.279759734 24.56184293 1.262964073 1.161805093 0.028789064 0.204407688 2021.047422 2709585.112 0.037577731 0.057468434 5.25E-07 6.279759734 -0.10115898 IQEQESS(ph)GEEDSDLSPEER ddPTM_HeLa_Curcumin_4h_R1 1 IQEQESSGEEDSDLSPEER 19 0 E7EMN6;Q6NXS1;P41236 E7EMN6 PPP1R2;PPP1R2P3 Protein phosphatase inhibitor 2-like protein 3;Protein phosphatase inhibitor 2 1 0 IQEQES(0.095)S(0.905)GEEDSDLSPEER 267.69 2.66E-55 21933000 1347.2 1709.5 1543.4 1560.7 1518.7 1537.4 960.45 1424.9 1470.3 1228.2 TRUE FALSE FALSE 1240.567698 1857.261563 1600.599762 1554.242237 1500.590494 1218.52591 987.3976421 1859.345451 1309.011769 1270.879859 0.976148682 1.46139822 1.259442229 1.222965512 1.180749293 0.958804958 0.776940193 1.46303794 1.030004339 1 10.31161194 IQEVADELQK ddPTM_HeLa_Curcumin_4h_R1 1 IQEVADELQK 10 0 C9JPM4;P18085;C9JAK5 C9JPM4 ARF4 ADP-ribosylation factor 4 0 0 128.01 0.0017294 1404800 843.09 584.44 606.49 723.03 704.97 797.69 526.05 763.21 843.03 660.41 FALSE FALSE TRUE 776.3585369 634.9563894 628.9670529 720.0382934 696.5636932 632.2401022 540.8095472 995.9092156 750.5517182 683.3591983 1.136091442 0.929169302 0.920404751 1.053674693 1.01932292 0.925194398 0.79139865 1.457372957 1.098326795 1 9.4165003 -7.260883569 24.54841234 1.0642654 0.999984944 0.023380682 0.168332789 127.1337331 5615097.226 0.02671849 0.031708751 5.48E-08 7.260883569 -0.064280456 IQFK(ac)PDDGTTPER ddPTM_HeLa_Curcumin_4h_R1 2 IQFKPDDGTTPER 13 1 Q96AE4;E9PEB5;Q96AE4-2 Q96AE4 FUBP1 Far upstream element-binding protein 1 0 1 ; IQFK(1)PDDGTTPER;IQFK(1)PDDGTTPER 164.13 2.05E-05 4341700 1266.32 1567.52 866.94 1175.27 2248.75 2977.9 2132.7 2364.24 2855.8 1327.97 FALSE TRUE FALSE 1166.089436 1703.009444 899.069559 1170.407044 2221.935125 2360.249972 2192.537822 3085.085892 2542.525885 1374.116859 0.848610093 1.239348337 0.65428901 0.85175219 1.616991387 1.717648654 1.595597789 2.24514085 1.850298152 1 10.42428898 -5.66817759 3.942375878 0.92462097 1.805763796 0.466871144 0.360324147 0.070375384 2.063814638 0.0295508 0.060788939 2.15E-06 5.66817759 0.881142825 IQFVEGPVEPGKPT(ph)SPEHVVYEGETVTR ddPTM_HeLa_Curcumin_4h_R1 2 IQFVEGPVEPGKPTSPEHVVYEGETVTR 28 1 Q9H7C4-2;Q9H7C4;C9JTN4;C9JSS1 Q9H7C4-2 SYNC Syncoilin 1 0 IQFVEGPVEPGKPT(0.877)S(0.102)PEHVVY(0.02)EGET(0.001)VTR;IQFVEGPVEPGKPT(0.497)S(0.497)PEHVVY(0.005)EGET(0.001)VT(0.001)R ; 66.437 0.00031818 35932000 3506.15 2804.74 3477.9 2996.09 3967.74 3629.47 3014.8 3239.47 3322.39 2546.47 TRUE FALSE FALSE 3228.634528 3047.169228 3606.794033 2983.692973 3920.427292 2876.677009 3099.387174 4227.16949 2957.932129 2634.959643 1.225307012 1.156438671 1.368823254 1.132348642 1.487850982 1.091734751 1.176256032 1.604263466 1.122572081 1 11.36356515 -13.52287874 0.108180722 0.051471625 1.456654623 0.291392633 0.152179249 81.63353366 0.650697055 17.11711988 0.926383398 3.00E-14 13.52287874 1.405182998 LRLDTGS(ph)PEPETR ddPTM_HeLa_Curcumin_4h_R1 3 LRLDTGSPEPETR 13 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 0 LRLDT(0.362)GS(0.625)PEPET(0.012)R;LRLDT(0.099)GS(0.9)PEPET(0.001)R;LRLDT(0.011)GS(0.988)PEPETR ;; 104.26 0.0023075 124833000 9308.8 7166.4 7659 8407.4 6814.6 8535.2 4523.3 1288.81 9453 7591.4 TRUE FALSE FALSE 8571.998657 7785.831683 7942.849278 8372.612406 6733.340346 6764.903308 4650.211624 1681.762236 8416.02955 7855.200585 1.091251403 0.991169048 1.011158046 1.065868696 0.857182483 0.861200581 0.591991455 0.21409539 1.071395881 1 12.9394324 -4.452499046 1.026011715 1.036618169 7.88E-19 0.960360137 0.052178011 0.190511034 0.191932425 0.008361313 0.199610986 3.53E-05 4.452499046 -1.036618169 down IQIVTAVDASGS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 IQIVTAVDASGSPK 14 0 C9JKS0;P49116;P49116-2;C9JMI6 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 0 IQIVT(0.001)AVDAS(0.202)GS(0.797)PK 97.352 0.0064643 29218000 2083.1 2124.2 2333.3 2231.9 1807.4 2187 1826.2 1163.2 2534.7 2076 TRUE FALSE FALSE 1918.220437 2307.806383 2419.774151 2222.664989 1785.847935 1733.391547 1877.438257 1517.854325 2256.649752 2148.140845 0.892967722 1.074327313 1.126450417 1.034692392 0.831345831 0.806926395 0.873982849 0.70658976 1.050512938 1 11.06887287 -5.673106104 6.083644192 0.978614687 0.806840368 0.631793357 0.078685839 0.147198132 8.196877446 0.012967538 0.026082132 2.12E-06 5.673106104 -0.171774319 IQKPNEVS(ph)SPPTTSAVIPPAVPQAQHLVAQPR ddPTM_HeLa_Curcumin_4h_R1 1 IQKPNEVSSPPTTSAVIPPAVPQAQHLVAQPR 32 1 Q86TC9;A0A087WX60;Q86TC9-2;Q86TC9-3 Q86TC9 MYPN Myopalladin 1 0 IQKPNEVS(0.475)S(0.475)PPT(0.015)T(0.015)S(0.02)AVIPPAVPQAQHLVAQPR 82.169 3.89E-07 30235000 919.25 863.97 657.02 1033.6 865.88 1154.3 962.48 698.58 1071.5 836.97 TRUE FALSE FALSE 846.4903925 938.647717 681.3697392 1029.323237 855.5549465 914.8851684 989.4845984 911.5738261 953.9591308 866.0546452 0.97740991 1.083820429 0.78675144 1.188519966 0.987876402 1.056382728 1.142519821 1.052559248 1.10149993 1 9.758314247 IQKPNEVSSPPTTS(ph)AVIPPAVPQAQHLVAQPR ddPTM_HeLa_Curcumin_4h_R1 1 IQKPNEVSSPPTTSAVIPPAVPQAQHLVAQPR 32 1 Q86TC9;A0A087WX60;Q86TC9-2;Q86TC9-3 Q86TC9 MYPN Myopalladin 1 0 IQKPNEVS(0.116)S(0.116)PPT(0.116)T(0.116)S(0.536)AVIPPAVPQAQHLVAQPR 75.103 7.68E-06 18714000 989.25 674.53 626.21 716.62 789.98 1242.3 818.72 572.81 1010.5 659.25 TRUE FALSE FALSE 910.9498186 732.8333676 649.4178935 713.6548163 780.5600045 984.6329764 841.6910797 747.4571321 899.6506781 682.1588884 1.335392434 1.074285449 0.952003858 1.046170956 1.144249555 1.44340709 1.233863685 1.095722924 1.318828639 1 9.413964001 -9.681846625 1.556122353 1.000224728 1.190255073 0 0.168848931 0.570259431 2.492262701 0.110087453 0.024633656 2.08E-10 9.681846625 0.190030345 IQNDAGVR ddPTM_HeLa_Curcumin_4h_R1 2 IQNDAGVR 8 0 Q96I24;Q96I24-2;A0A087WTP3;Q92945;M0R0I5;Q96AE4;E9PEB5;Q96AE4-2 Q96I24;A0A087WTP3;Q96AE4 FUBP3;KHSRP;FUBP1 Far upstream element-binding protein 3;Far upstream element-binding protein 2;Far upstream element-binding protein 1 0 0 ; ; 134.81 2.34E-08 2455300 6658.5 5543 5457.3 5057.9 5756.6 7056.4 5544.8 4517.4 5913.2 6109.1 FALSE FALSE TRUE 6131.472699 6022.112221 5659.552339 5036.97175 5687.956305 5592.823098 5700.372165 5894.734464 5264.536754 6321.39077 0.969956284 0.952656218 0.895301769 0.796813855 0.899795079 0.884745668 0.901759181 0.932505943 0.832813054 1 12.62602629 -6.899281894 2.479516453 0.985708233 0.881916292 0 0.058649666 0.128158883 1.60321587 0.005854287 0.007896325 1.26E-07 6.899281894 -0.103791942 IQNMQHLK(ac)KEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 IQNMQHLKKEKR 12 3 H3BU77 H3BU77 CCDC179 Coiled-coil domain-containing protein 179 0 2 IQNMQHLK(0.5)K(0.5)EK(1)R 49.081 0.016571 0 375.46 435.42 372.58 592.09 581.84 641.28 591.08 499.21 635.5 587.23 FALSE TRUE FALSE 345.7419448 473.0557646 386.3881426 589.6400885 574.901938 508.2712993 607.664114 651.4168309 565.7872399 607.6361988 0.568994977 0.778518076 0.635887301 0.970383413 0.946128521 0.836473041 1.000045941 1.072050731 0.931128266 1 9.247064008 -6.2283299 24.29458965 0.77871917 0.95877185 0.331847107 0.128983065 578.1809862 424248.9422 0.026238611 0.043509711 5.91E-07 6.2283299 0.18005268 IQPAGNTS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 IQPAGNTSPR 10 0 H0Y5S9;H0Y682;P49674 H0Y5S9 CSNK1E Casein kinase I isoform epsilon 1 0 IQPAGNT(0.08)S(0.92)PR;IQPAGNT(0.011)S(0.989)PR;IQPAGNT(0.023)S(0.977)PR;IQPAGNT(0.039)S(0.961)PR ;;; 118.23 0.0048725 1263040000 34740.8 28991.7 29567.8 31376.8 29045.5 32530.7 23530.2 11727 30941.3 28600.3 TRUE FALSE FALSE 31991.02902 31497.61336 30663.60868 31246.97112 28699.15138 25783.46612 24190.39408 15302.50832 27547.1168 29594.1583 1.080991346 1.064318608 1.036137212 1.055849293 0.969757311 0.871234987 0.817404362 0.51707868 0.930829542 1 14.8530248 -3.968758446 0.804189843 1.042927355 6.17E-19 0.913821422 0.047414504 0.561835579 0.191462015 0.006282803 0.582230951 0.000107459 3.968758446 -1.042927355 IQPEDMFVCDINEKDISGPS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 IQPEDMFVCDINEKDISGPSPSK 23 1 S4R3D6;Q96GX9-3;Q96GX9 S4R3D6 APIP Methylthioribulose-1-phosphate dehydratase 1 0 IQPEDMFVCDINEKDIS(0.006)GPS(0.855)PS(0.139)K;IQPEDMFVCDINEKDIS(0.01)GPS(0.784)PS(0.206)K ; 80.355 0.00023611 170752000 4019.3 2792.5 3147.7 3721.8 3008.2 3844.5 2954.9 3207.1 4242.4 3430.7 TRUE FALSE FALSE 3701.168164 3033.871257 3264.356531 3706.400178 2972.32918 3047.107364 3037.806541 4184.930026 3777.019334 3549.91657 1.042607084 0.854631707 0.919558662 1.044080926 0.837295503 0.858360275 0.855740264 1.178881234 1.063974113 1 11.7935694 -7.284492519 24.60943747 1.020120015 0.929256968 0.162914386 0.101430485 872.6341894 931542.2966 0.01637276 0.018730069 5.19E-08 7.284492519 -0.090863047 IQPEDMFVCDINEKDISGPS(ph)PSKK ddPTM_HeLa_Curcumin_4h_R1 2 IQPEDMFVCDINEKDISGPSPSKK 24 2 S4R3D6;Q96GX9-3;Q96GX9 S4R3D6 APIP Methylthioribulose-1-phosphate dehydratase 1 0 IQPEDMFVCDINEKDIS(0.006)GPS(0.909)PS(0.085)KK;IQPEDMFVCDINEKDIS(0.03)GPS(0.909)PS(0.061)KK ; 72.228 0.00060119 147548000 3992.5 2450.9 2964.4 2772.9 2774 3967.4 2394.4 2783.6 3781.8 3271.2 TRUE FALSE FALSE 3676.489412 2662.744875 3074.263272 2761.426475 2740.921862 3144.516518 2461.58042 3632.306826 3366.946002 3384.873957 1.08615253 0.786659979 0.908235672 0.815813679 0.80975596 0.928990727 0.727229566 1.073099581 0.994703509 1 11.7248864 -7.266663251 24.99571075 1.040683141 0.859206965 0.389753937 0.09266598 260.6235528 1247055.15 0.014307834 0.01661573 5.41E-08 7.266663251 -0.181476177 IQPEEKPVEVS(ph)PAVTK ddPTM_HeLa_Curcumin_4h_R1 2 IQPEEKPVEVSPAVTK 16 1 Q8N0X7 Q8N0X7 SPG20 Spartin 1 0 IQPEEKPVEVS(0.997)PAVT(0.003)K;IQPEEKPVEVS(0.997)PAVT(0.003)K ; 102.07 0.0010371 57116000 7360.2 5523.3 6367.7 7382.1 6965.8 12186 10903.7 4172 6847.9 5416.6 TRUE FALSE FALSE 6777.632404 6000.709441 6603.692564 7351.554826 6882.737385 9658.486235 11209.62848 5444.023594 6096.702503 5604.826447 1.20924929 1.070632516 1.178215352 1.311647184 1.228001875 1.72324448 1.999995643 0.971309932 1.087759373 1 12.45245399 -5.602392365 1.823488526 1.110202419 1.596584094 0.338329966 0.255729507 0.253153729 1.684325173 0.03679339 0.092840964 2.50E-06 5.602392365 0.486381676 IQPFDDDEDEDIWEDSDTR ddPTM_HeLa_Curcumin_4h_R1 1 IQPFDDDEDEDIWEDSDTR 19 0 T1ECW5;O75170-6;O75170-2;O75170-4;O75170-3;O75170-5;O75170;A0A0A0MSJ8 T1ECW5 PPP6R2 Serine/threonine-protein phosphatase 6 regulatory subunit 2 0 0 170.42 4.43E-05 9603700 2458.3 2099.9 1762.4 2217.7 2196 2361.4 1807.5 1744.6 2578.5 2109.4 FALSE FALSE TRUE 2263.722961 2281.405999 1827.716094 2208.523745 2169.814134 1871.619022 1858.213585 2276.520509 2295.645001 2182.701493 1.037119812 1.045221257 0.837364202 1.011830409 0.994095684 0.857478234 0.851336562 1.042982981 1.051744826 1 11.09189913 -6.798234933 24.99947698 1.020095525 0.931818251 0.341150449 0.067742164 157.6670124 107120.9002 0.010500277 0.013800267 1.59E-07 6.798234933 -0.088277274 IQPLEPDS(ph)PTGLSENPTPATEK ddPTM_HeLa_Curcumin_4h_R1 1 IQPLEPDSPTGLSENPTPATEK 22 0 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 0 IQPLEPDS(0.784)PT(0.215)GLSENPTPATEK 112.8 7.90E-06 6023000 4082.1 3782.5 3689.6 3888 4306.9 5578.5 4460.6 5029.8 4496.8 3506.1 TRUE FALSE FALSE 3758.997478 4109.442446 3826.339822 3871.912486 4255.54303 4421.456217 4585.752431 6563.362866 4003.51229 3627.936714 1.036125427 1.132721646 1.054687588 1.067249181 1.172992631 1.218724737 1.264011143 1.809117243 1.103523189 1 11.82493357 -1 0.638837271 1.030350926 62.82331409 0.932734423 0.057624052 28.62410424 0.178394068 0.009213788 2500.625281 0.1 1 61.79296316 IQPQPPDEDGDHS(ph)DKEDEQPQVVVLK ddPTM_HeLa_Curcumin_4h_R1 4 IQPQPPDEDGDHSDKEDEQPQVVVLK 26 1 Q96AT1 Q96AT1 KIAA1143 Uncharacterized protein KIAA1143 1 0 IQPQPPDEDGDHS(1)DKEDEQPQVVVLK;IQPQPPDEDGDHS(1)DKEDEQPQVVVLK;IQPQPPDEDGDHS(1)DKEDEQPQVVVLK;IQPQPPDEDGDHS(1)DKEDEQPQVVVLK ;;; 93.407 4.40E-06 608979000 17388.8 15279.8 17055.4 18031.4 17172.8 18206.3 16633.4 15949.8 19260.9 16982 TRUE FALSE FALSE 16012.45813 16600.51783 17687.48813 17956.79084 16968.02558 14430.10815 17100.08844 20812.8206 17148.02746 17572.12324 0.91124208 0.944707569 1.006565222 1.021890787 0.965621817 0.821193202 0.973137293 1.18442264 0.975865422 1 14.1010009 -6.772154494 24.62682843 0.955912004 0.98637891 0.037648917 0.085583438 653.3723398 1501660.015 0.014362091 0.018984678 1.69E-07 6.772154494 0.030466906 IQPQPPDEDGDHS(ph)DKEDEQPQVVVLKK ddPTM_HeLa_Curcumin_4h_R1 2 IQPQPPDEDGDHSDKEDEQPQVVVLKK 27 2 Q96AT1 Q96AT1 KIAA1143 Uncharacterized protein KIAA1143 1 0 IQPQPPDEDGDHS(1)DKEDEQPQVVVLKK;IQPQPPDEDGDHS(1)DKEDEQPQVVVLKK ; 50.158 0.0053392 103403000 3620 3075.5 2943.9 3544.4 2808.5 3361.3 3144.1 2972.6 3858.4 3647.8 TRUE FALSE FALSE 3333.47318 3341.332516 3053.003524 3529.734212 2775.010472 2664.12849 3232.314984 3878.932056 3435.143173 3774.560778 0.883142007 0.885224192 0.808836764 0.935137734 0.735187651 0.705811523 0.856342015 1.027651238 0.910077589 1 11.88209306 -8.497781966 0.519905534 1.005779979 0.836702066 0.143477919 0.091075635 0.902323402 0.498573972 0.069925719 0.026573725 3.18E-09 8.497781966 -0.169077913 IQQEIAVQNPLVSER ddPTM_HeLa_Curcumin_4h_R1 1 IQQEIAVQNPLVSER 15 0 J3KR44;F5GYJ8;Q96FW1;F5GYN4 J3KR44 OTUB1 Ubiquitin thioesterase OTUB1 0 0 89.26 0.018114 0 0 0 0 0 0 0 0 0 0 71.219 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 73.69385495 0 0 0 0 0 0 0 0 0 1 6.203472418 -9.157829429 0.677150941 1.083625666 2.50E-23 0 0.307667284 0.066591669 0.049088893 0.041658111 0.0090835 6.95E-10 9.157829429 -1.083625666 IQQFDDGGS(ph)DEEDIWEEK ddPTM_HeLa_Curcumin_4h_R1 1 IQQFDDGGSDEEDIWEEK 18 0 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5;Q5H9R7-3 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 1 0 IQQFDDGGS(1)DEEDIWEEK 156.36 2.34E-05 25509000 5920.4 4951.2 5551.8 5467 5735.5 6305.6 5207 4369 6305.1 5368.2 TRUE FALSE FALSE 5451.794093 5379.159666 5757.554592 5444.379003 5667.107908 4997.747481 5353.094406 5701.087988 5613.446305 5554.74455 0.981466212 0.968390106 1.036511137 0.980131301 1.020228357 0.899725889 0.963697675 1.026345665 1.010567858 1 12.43950485 IQQFDDGGS(ph)DEEDIWEEKHIAFTPESQR ddPTM_HeLa_Curcumin_4h_R1 3 IQQFDDGGSDEEDIWEEKHIAFTPESQR 28 1 H0YEN2;E9PQP7;H7BXH2;E9PKF6;Q5H9R7-4;Q5H9R7-6;Q5H9R7-2;Q5H9R7;Q5H9R7-5;Q5H9R7-3 H0YEN2 PPP6R3 Serine/threonine-protein phosphatase 6 regulatory subunit 3 1 0 IQQFDDGGS(1)DEEDIWEEKHIAFTPESQR;IQQFDDGGS(1)DEEDIWEEKHIAFTPESQR;IQQFDDGGS(1)DEEDIWEEKHIAFTPESQR ;; 65.349 0.00026538 38799700 4610.95 3622.13 3544.2 4331.26 2990.59 4584.4 2927.92 2929.92 5978.5 5307.7 TRUE FALSE FALSE 4245.988442 3935.210777 3675.55117 4313.338394 2954.929167 3633.543763 3010.069555 3823.23912 5322.673507 5492.14218 0.773102426 0.716516552 0.669238168 0.785365392 0.538028527 0.66158953 0.548068396 0.696128941 0.969143429 1 12.42315326 -8.408734707 0.291399254 1.092851366 0.584881696 0.809422809 0.063912531 0.639560877 0.122613647 0.122428509 0.048043804 3.90E-09 8.408734707 -0.507969669 AST(ph)PDWVSEGPQPGLRR ddPTM_HeLa_Curcumin_4h_R1 2 ASTPDWVSEGPQPGLRR 17 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 AS(0.017)T(0.983)PDWVSEGPQPGLRR;AS(0.075)T(0.921)PDWVS(0.004)EGPQPGLRR ; 119.17 0.006785 57735000 6369.6 5249.7 5584.5 5716 4590.9 5059.6 2964.33 2122.96 7663.2 6441.1 TRUE FALSE FALSE 5865.439439 5703.460676 5791.466483 5692.348707 4536.156516 4010.181927 3047.501122 2770.240731 6822.566132 6664.927746 0.880045465 0.855742312 0.868946627 0.854075081 0.680601004 0.601684231 0.457244435 0.415644526 1.023651927 1 12.70237352 -4.450342657 0.394952442 0.966229257 4.14E-15 0.959575761 0.040853708 0.673193229 0.079258773 0.012459025 0.298882573 3.55E-05 4.450342657 -0.966229257 down IQS(ph)GLGALSR ddPTM_HeLa_Curcumin_4h_R1 1 IQSGLGALSR 10 0 E9PIE3;Q969G5 E9PIE3 PRKCDBP Protein kinase C delta-binding protein 1 0 IQS(0.997)GLGALS(0.003)R 91.307 0.018346 5559800 1418.9 1437.1 1577.6 1443.7 1647.6 1719.3 1365.9 1484.9 1662.4 1576.4 TRUE FALSE FALSE 1306.592568 1561.31652 1636.067244 1437.726352 1627.953446 1362.697799 1404.223478 1937.639174 1480.038879 1631.179783 0.801010766 0.957170103 1.002996274 0.881402754 0.998022084 0.835406259 0.860863709 1.187875913 0.907342584 1 10.67170008 -4.254904025 24.73373256 0.91167958 1.187876059 0.584059923 0.068736171 431.0395432 1631263.802 0.011730335 0.148206223 5.56E-05 4.254904025 0.276196479 TAAILHGGS(ph)PDFVGNGK ddPTM_HeLa_Curcumin_4h_R1 2 TAAILHGGSPDFVGNGK 17 0 H0YME5;Q9P2K8-2;Q9P2K8;Q9P2K8-3 H0YME5 EIF2AK4 Eukaryotic translation initiation factor 2-alpha kinase 4 1 0 T(0.001)AAILHGGS(0.999)PDFVGNGK;T(0.001)AAILHGGS(0.999)PDFVGNGK ; 133.25 0.00034718 48822000 6393 5342.8 5763.5 6119.3 5986 6271.3 3907.4 1862.82 6476.4 5928.7 TRUE FALSE FALSE 5886.987304 5804.607825 5977.10038 6093.979958 5914.62086 4970.561688 4017.031128 2430.785243 5765.955123 6134.721884 0.959617635 0.946189238 0.974306659 0.993358798 0.964122086 0.810234234 0.654802484 0.396233976 0.939888594 1 12.58278223 -4.447386605 1.119650251 0.979916885 0.224694622 0.982845887 0.024310987 0.103022825 0.128717891 0.003699718 0.084118319 3.57E-05 4.447386605 -0.755222264 down IQVEQTRDEDLDTDS(ph)LD ddPTM_HeLa_Curcumin_4h_R1 1 IQVEQTRDEDLDTDSLD 17 1 V9GYT7 V9GYT7 PSIP1 1 0 IQVEQTRDEDLDT(0.001)DS(0.999)LD 232.26 2.43E-21 32447000 4332.9 3459.9 3140 3561.7 3227.9 4403.6 3892.8 3602.1 3939.5 3949.2 TRUE FALSE FALSE 3989.946393 3758.958339 3256.371162 3546.962629 3189.409401 3490.243721 4002.021491 4700.363708 3507.346706 4086.434406 0.976388214 0.91986264 0.796873469 0.867984721 0.780487115 0.854104917 0.979343137 1.150235937 0.858290225 1 11.99662686 -7.240432406 3.599808744 0.989541145 0.89607014 0 0.107168768 0.344498894 9.530926063 0.017624915 0.021079989 5.75E-08 7.240432406 -0.093471005 IQVEQTRDEDLDTDSLD ddPTM_HeLa_Curcumin_4h_R1 1 IQVEQTRDEDLDTDSLD 17 1 V9GYT7 V9GYT7 PSIP1 0 0 210.91 3.53E-10 15722000 3435.1 2647.8 3062.4 3375 3194.3 3643.6 2602.9 2443.9 3154.8 2945.3 FALSE FALSE TRUE 3163.20821 2876.664034 3175.895238 3361.035144 3156.210059 2887.876288 2675.930369 3189.03386 2808.726333 3047.648956 1.037917508 0.943896123 1.042080398 1.102828834 1.035621262 0.947575108 0.878031036 1.046391466 0.921604284 1 11.57348102 -5.255505159 23.95595234 1.022011546 0.949402376 0.122540601 0.062084341 271.1410311 1094565.12 0.00733059 0.018145443 5.55E-06 5.255505159 -0.07260917 IQVLQQQADDAEER ddPTM_HeLa_Curcumin_4h_R1 2 IQVLQQQADDAEER 14 0 A0A087WWU8;P06753-2;P06753-5;P06753-3;P06753-6;P06753-4;D6R904;Q5VU61 A0A087WWU8 TPM3 Tropomyosin alpha-3 chain 0 0 ; ; 267.93 3.08E-49 20228800 2850.21 2517.48 2456.57 2825.92 3256.96 3102.21 2630.47 2815.32 2282.2 2006.53 FALSE FALSE TRUE 2624.612871 2735.079754 2547.612645 2814.227092 3218.122879 2458.776677 2704.273909 3673.698108 2031.84837 2076.256768 1.264108039 1.317312866 1.227021958 1.355433073 1.549963824 1.184235358 1.302475662 1.769385253 0.978611317 1 11.01976916 -7.048282382 0.050360512 6.93E-13 2.541488818 0.609095417 0.139695799 22.7271766 0.879438059 21.09839455 22.71901036 8.95E-08 7.048282382 2.541488818 IQVTEET(ph)S(ph)LVLQTLGYT(ph)CT(ph)CRGIINVK ddPTM_HeLa_Curcumin_4h_R1 1 IQVTEETSLVLQTLGYTCTCRGIINVK 27 1 Q08462-2;Q08462 Q08462-2 ADCY2 Adenylate cyclase type 2 4 0 IQVT(0.11)EET(0.779)S(0.885)LVLQT(0.226)LGY(0.497)T(0.563)CT(0.94)CRGIINVK 65.194 0.0016326 0 1124.3 987.08 895.35 953.94 907.02 1304.3 976.99 1033.2 1145.4 1029.3 TRUE FALSE FALSE 1035.310469 1072.398797 928.5324586 949.992849 896.2043789 1033.773478 1004.40171 1348.217924 1019.752486 1065.068098 0.97206035 1.006882845 0.871805718 0.891955031 0.841452655 0.970617258 0.943039897 1.265851381 0.957452849 1 10.05672996 -4.259385088 24.86685415 0.960950998 1.265851494 0.746345698 0.055831568 76.69800163 928342.5556 0.00876768 0.076786883 5.50E-05 4.259385088 0.304900496 IQVWHEEHR ddPTM_HeLa_Curcumin_4h_R1 2 IQVWHEEHR 9 0 P26038 P26038 MSN Moesin 0 0 ; ; 100.02 0.0038226 47780000 4962.5 2567.5 3972 3250.7 4506 5293.8 3911.3 4308.4 3674.5 3352.7 FALSE FALSE TRUE 4569.712889 2789.423259 4119.205814 3237.249465 4452.268893 4195.806207 4021.040551 5622.011327 3271.416543 3469.206075 1.317221517 0.804052339 1.187362677 0.933138417 1.283368239 1.20944277 1.159066502 1.620546951 0.94298709 1 11.76038983 -1.724398103 1.144631028 1.122969984 199.998326 0.481189103 0.161712621 456.9033315 1.899182526 0.024707473 237019.4377 0.018862615 1.724398103 198.8753561 IRAEEEDLAAVPFLAS(ph)DNEEEEDEKGNSGSLIR ddPTM_HeLa_Curcumin_4h_R1 2 IRAEEEDLAAVPFLASDNEEEEDEKGNSGSLIR 33 2 A0A3B3IRP6;A0A0J9YVP0;O95714 A0A3B3IRP6 HERC2 E3 ubiquitin-protein ligase HERC2 1 0 IRAEEEDLAAVPFLAS(1)DNEEEEDEKGNSGSLIR;IRAEEEDLAAVPFLAS(1)DNEEEEDEKGNSGSLIR ; 99.093 1.85E-11 91935000 5362.3 4207.2 4508.8 4900.5 4313.8 4307.8 3406.1 2559.97 5087 4603.8 TRUE FALSE FALSE 4937.868297 4570.851621 4675.900094 4880.223029 4262.360752 3414.313721 3501.665999 3340.493068 4528.968827 4763.781707 1.03654378 0.959500645 0.981552133 1.024443043 0.894743087 0.716723379 0.73506013 0.70122715 0.950708724 1 12.21789159 -5.438780436 2.480992386 1.010530685 0.715038726 0.940319207 0.030632336 0.038791456 0.46512332 0.003991379 0.010061069 3.64E-06 5.438780436 -0.29549196 IRAENGTGS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 IRAENGTGSSPR 12 1 M0R102;Q9NQT4;M0R050 M0R102 EXOSC5 Exosome complex component RRP46 1 0 IRAENGTGS(0.723)S(0.277)PR 95.477 0.0051713 46842000 3876.5 3034.6 3499.2 3586.3 2999.1 3795.9 3354.8 2677.3 3779.8 3435.6 TRUE FALSE FALSE 3569.670935 3296.897302 3628.88343 3571.460841 2963.337691 3008.587551 3448.926659 3493.596445 3365.165397 3554.986844 1.004130561 0.927400704 1.02078674 1.004634053 0.833572056 0.846300615 0.970165801 0.982731188 0.946604177 1 11.79562851 -5.795710845 24.99968829 0.9975209 0.908198198 0.31958278 0.051910133 130.5379545 95221.96985 0.007455243 0.013514234 1.60E-06 5.795710845 -0.089322702 GFSDS(ph)GGGPPAK ddPTM_HeLa_Curcumin_4h_R1 1 GFSDSGGGPPAK 12 0 Q9H307;G3V5F0;G3V579 Q9H307 PNN Pinin 1 0 GFS(0.376)DS(0.624)GGGPPAK 140.63 0.0011703 13538000 1476.2 1197.9 1378.7 1713.8 1396.3 2069.1 2674.6 19524 0 1026.4 TRUE FALSE FALSE 1359.357212 1301.441138 1429.795835 1706.70875 1379.650034 1639.945336 2749.642078 25476.77772 0 1062.067324 1.279916237 1.225384784 1.346238419 1.606968515 1.299023145 1.544106762 2.588952712 23.98791221 0 1 10.0526595 -4.259657917 4.512352044 1.244518249 25.52400283 0.996016155 0.430868887 0.005360684 0.275952048 0.039093902 0.41270397 5.50E-05 4.259657917 24.27948458 up IRDGWQVEEADDWLR ddPTM_HeLa_Curcumin_4h_R1 2 IRDGWQVEEADDWLR 15 1 E9PK47;P06737-2;P06737 E9PK47 PYGL "Alpha-1,4 glucan phosphorylase;Glycogen phosphorylase, liver form" 0 0 ; ; 219.41 1.64E-14 13706400 2762.2 1772.46 2026.12 2277.9 1883.94 2982.1 2031.18 2432.3 2765.4 2390.52 FALSE FALSE TRUE 2543.568955 1925.663544 2101.20979 2268.474653 1861.475246 2363.578845 2088.169444 3173.897073 2462.042539 2473.590392 1.028290279 0.778489256 0.849457451 0.917077727 0.752539811 0.95552556 0.844185622 1.283113438 0.995331542 1 11.27239091 -7.340974426 24.99997993 1.013359426 0.902302707 0.089011093 0.138824782 158.1302217 49703.29944 0.022198026 0.025384405 4.56E-08 7.340974426 -0.111056719 IREEFPDR ddPTM_HeLa_Curcumin_4h_R1 1 IREEFPDR 8 1 P04350;M0QYM7;M0R042;Q9BUF5;K7ESM5;K7ES63 P04350;Q9BUF5 TUBB4A;TUBB6 Tubulin beta-4A chain;Tubulin beta-6 chain 0 0 90.601 0.017732 55462000 2191.1 1641.5 2206.2 2062.8 1987.3 2056.6 1853.2 1774.4 2398.3 2067.9 FALSE FALSE TRUE 2017.672123 1783.383946 2287.963713 2054.26468 1963.602745 1630.037977 1905.195804 2315.406392 2135.21249 2139.759371 0.942943468 0.8334507 1.069262153 0.960044717 0.917674563 0.761785647 0.89037853 1.082087277 0.99787505 1 11.06323285 -5.721574581 4.77801709 0.968112127 0.899265266 0.072799372 0.091361707 0.350931349 18.07676239 0.013127643 0.026249903 1.90E-06 5.721574581 -0.06884686 IREEYPDR ddPTM_HeLa_Curcumin_4h_R1 6 IREEYPDR 8 1 Q5JP53;P07437;Q5ST81;A0A075B736;Q5SQY0;A6NNZ2;CON__ENSEMBL:ENSBTAP00000025008;Q9H4B7;P68371;Q3ZCM7;Q9BVA1;Q13885 Q5JP53;P68371;Q9BVA1 TUBB;TUBB8;TUBB1;TUBB4B;TUBB2B;TUBB2A Tubulin beta chain;Tubulin beta-8 chain-like protein LOC260334;Tubulin beta-1 chain;Tubulin beta-4B chain;Tubulin beta-8 chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 0 ;;;;; ;;;;; 128.12 0.00088391 2200247000 30454.7 24474.5 28087.7 28439.3 28528.8 32174.2 23971.7 24541.3 29451.4 25569.4 FALSE FALSE TRUE 28044.17836 26589.96672 29128.65487 28321.62571 28188.61269 25500.90824 24644.28139 32023.8294 26220.6551 26457.93475 1.059953418 1.00499026 1.100942124 1.070439775 1.065412435 0.963828375 0.931451439 1.210367691 0.991031815 1 14.69141283 -4.240372685 24.42632357 1.02826613 1.210367939 0.553237688 0.050692007 2488.797936 2885642.394 0.007129153 0.42679998 5.75E-05 4.240372685 0.182101809 IRELESQISELQEDLESER ddPTM_HeLa_Curcumin_4h_R1 1 IRELESQISELQEDLESER 19 1 P35579 P35579 MYH9 Myosin-9 0 0 195.48 3.08E-10 8900100 979.22 640 825.47 861.82 808.21 990.83 823.53 723.51 872.86 632.56 FALSE FALSE TRUE 901.7137037 695.3187482 856.0626444 858.2540172 798.5726236 785.320689 846.6360354 944.1048684 777.1094418 654.5414129 1.377626665 1.062299091 1.30788156 1.311229512 1.220049042 1.199802906 1.293479708 1.442391344 1.187257867 1 9.354340664 -9.459429105 1.074141877 0.99242423 1.278693792 0.240612182 0.112416915 0.34522568 0.681197472 0.077893904 0.017290714 3.47E-10 9.459429105 0.286269563 IRETTDFK ddPTM_HeLa_Curcumin_4h_R1 1 IRETTDFK 8 1 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 99.139 0.013415 16010000 3184.2 2082 2796 2837.2 3309.2 5022.3 4182.3 3479.2 2822.7 2790.2 FALSE FALSE TRUE 2932.16721 2261.958803 2899.62222 2825.460418 3269.739951 3980.618367 4299.644082 4539.992064 2513.056872 2887.159242 1.015589015 0.783454812 1.004316692 0.97862992 1.132511121 1.378731837 1.489229973 1.572477194 0.870425446 1 11.49543497 -5.211819556 1.581712484 0.985421948 1.550169127 0.909124989 0.076400847 0.082060767 0.38160526 0.010572375 0.040321401 6.14E-06 5.211819556 0.564747179 IRKT(ph)IMQVS(ph)S(ph)GSR ddPTM_HeLa_Curcumin_4h_R1 1 IRKTIMQVSSGSR 13 2 K7EJ87 K7EJ87 POLR2E 3 0 IRKT(1)IMQVS(0.983)S(0.983)GS(0.033)R 64.588 0.018433 13215000 2200.5 1951.9 2277.9 2503.5 2306.5 159.72 849.81 508.51 2332.3 1997.8 TRUE FALSE FALSE 2026.328103 2120.613539 2362.320978 2493.14118 2278.996494 126.5922716 873.6533815 663.5523581 2076.452525 2067.223401 0.980217282 1.02582698 1.142750695 1.206033745 1.102443254 0.061237828 0.422621658 0.320987252 1.004464502 1 11.01347859 -5.26844253 24.98508342 1.027878597 0.283716179 0.91426988 0.111479408 112.5771429 401641.0252 0.016732971 0.038178758 5.39E-06 5.26844253 -0.744162418 GQSQLSNPTDDS(ph)WK ddPTM_HeLa_Curcumin_4h_R1 1 GQSQLSNPTDDSWK 14 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 1 0 GQSQLS(0.015)NPT(0.284)DDS(0.701)WK 152.11 0.00046048 30797000 5689.9 4609.2 4593.5 4801.5 4411.1 4204 3125.7 1231.7 4882.1 5258.7 TRUE FALSE FALSE 5239.538411 5007.59871 4763.739151 4781.632665 4358.500513 3332.043011 3213.39873 1607.23966 4346.545844 5441.439434 0.962895659 0.920270963 0.875455697 0.878744076 0.800983006 0.612345879 0.590542037 0.295370311 0.798786038 1 12.40977263 -4.44652774 0.5282715 0.985317563 1.71E-19 0.881986754 0.070372041 0.358330726 0.07577337 0.007286278 0.208787839 3.58E-05 4.44652774 -0.985317563 down IRT(ph)PSGEFLER ddPTM_HeLa_Curcumin_4h_R1 2 IRTPSGEFLER 11 1 B3KT28;B1ANM7;Q9UNN5-2;Q9UNN5 B3KT28 FAF1 FAS-associated factor 1 1 0 IRT(0.989)PS(0.011)GEFLER;IRT(0.755)PS(0.245)GEFLER ; 87.363 0.016563 11521600 2906.2 2336.33 2783.3 2938 2234.21 2674.6 2404.1 2728.3 3153.3 2320.7 TRUE FALSE FALSE 2676.171203 2538.271955 2886.451546 2925.843334 2207.568505 2119.857811 2471.552576 3560.14611 2807.390879 2401.344152 1.114447174 1.057021315 1.20201494 1.218418997 0.919305341 0.882779675 1.029237135 1.482563883 1.169091434 1 11.22962647 -9.250415295 0.851806507 0.996228681 1.101675104 0 0.16871132 1.872306918 2.302615753 0.130107273 0.031084299 5.62E-10 9.250415295 0.105446423 IRTPS(ph)GEFLER ddPTM_HeLa_Curcumin_4h_R1 1 IRTPSGEFLER 11 1 B3KT28;B1ANM7;Q9UNN5-2;Q9UNN5 B3KT28 FAF1 FAS-associated factor 1 1 0 IRT(0.183)PS(0.817)GEFLER 80.371 0.012049 21131000 1331 1218.1 1365 1402.6 1305 1497.8 1334.2 1301.1 1542.2 1284.4 TRUE FALSE FALSE 1225.649946 1323.387136 1415.588101 1396.796413 1289.438727 1187.139396 1371.634061 1697.7994 1373.024518 1329.032804 0.922211959 0.995752048 1.065126531 1.05098716 0.970208352 0.893235586 1.032054331 1.277469898 1.033100548 1 10.376161 -4.290675655 3.546439734 0.974819748 1.304199459 0.713426965 0.053140832 0.102564749 2.274073767 0.007850418 0.085610184 5.12E-05 4.290675655 0.329379711 IRVDVADQAQDKDRDDR ddPTM_HeLa_Curcumin_4h_R1 1 IRVDVADQAQDKDRDDR 17 3 E7EX17;P23588-2;P23588;F8VP89;F8W0K0;F8VSC7 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 0 60.968 0.0085875 110280000 2886.4 2541.8 2472.7 2852.8 2515.5 3194.1 2314.1 2434.6 2869.3 2703 FALSE FALSE TRUE 2657.938394 2761.501866 2564.340437 2840.995869 2485.504305 2531.607655 2379.027418 3176.898332 2554.544969 2796.929049 0.950305978 0.987333543 0.916841433 1.01575543 0.888654757 0.905138318 0.850585545 1.135852314 0.91333921 1 11.44962794 -9.331763904 0.457626091 1.013947511 0.947232594 0 0.080303409 4.758253506 1.276468976 0.149300381 0.020719748 4.66E-10 9.331763904 -0.066714916 IRVT(ph)T(ph)IAR ddPTM_HeLa_Curcumin_4h_R1 1 IRVTTIAR 8 1 Q5QPE1;F5H365;A0A2R8YFH5;Q15436-2;Q15436;Q15437 Q5QPE1 SEC23B;SEC23A Protein transport protein Sec23A;Protein transport protein Sec23B 2 0 IRVT(1)T(1)IAR 99.375 0.01376 16053000 4188.8 3534.8 3748 3745.3 3886.6 4994.6 3733.2 3536.3 3959.4 3679.2 TRUE FALSE FALSE 3857.25206 3840.332361 3886.904177 3729.802941 3840.254833 3958.663659 3837.943545 4614.501591 3525.063726 3807.051926 1.013186091 1.008741786 1.020974826 0.979708975 1.008721422 1.03982392 1.008114315 1.212093158 0.925930036 1 11.89445853 -4.261419517 24.00239661 1.008226269 1.21209324 0.818032017 0.029731529 0.140816782 167894.9692 0.001978985 0.015276592 5.48E-05 4.261419517 0.203866971 IS(ph)APNVDFNLEGPK ddPTM_HeLa_Curcumin_4h_R1 4 ISAPNVDFNLEGPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK;IS(1)APNVDFNLEGPK ;;; 222.51 2.27E-14 1837040000 18908.3 19537 17928.4 18748.6 20699.4 31735.1 30883.9 14224 24418.2 19094.4 TRUE FALSE FALSE 17411.6881 21225.69122 18592.84228 18671.02326 20452.57317 25152.88253 31750.41911 18560.83212 21739.58455 19757.92898 0.881250668 1.074287252 0.941031942 0.944988884 1.035157743 1.273052584 1.606971011 0.939411825 1.100296725 1 14.27014411 -5.322570163 3.383439955 0.954578432 1.310928107 0.358422512 0.164275892 0.141190258 3.205673075 0.020755303 0.051655832 4.76E-06 5.322570163 0.356349675 IS(ph)ASSATR ddPTM_HeLa_Curcumin_4h_R1 1 ISASSATR 8 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-3;A0A1B0GU60;A0A1B0GV30;P49023-4 A0A1B0GTU4;P49023-4 PXN Paxillin 1 0 IS(0.924)AS(0.076)SATR 120.31 0.0081791 610800000 3732.5 3180.6 3617.9 3775 3385.1 4795.2 4049.7 1062.7 3883.4 3567.1 TRUE FALSE FALSE 3437.068686 3455.516892 3751.982557 3759.38005 3344.734893 3800.621467 4163.323683 1386.712338 3457.400736 3691.056459 0.931188326 0.936186409 1.016506412 1.018510579 0.90617278 1.029683915 1.127949065 0.375695239 0.93669679 1 11.84981809 -4.252718067 24.98522597 0.979557958 0.37569493 0.895874124 0.062670657 255.0038635 730531.2655 0.008581632 0.136834936 5.59E-05 4.252718067 -0.603863028 IS(ph)DAELEAELEK ddPTM_HeLa_Curcumin_4h_R1 4 ISDAELEAELEK 12 0 Q8WUX9 Q8WUX9 CHMP7 Charged multivesicular body protein 7 1 0 IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK;IS(1)DAELEAELEK ;;; 225.86 8.28E-19 176647000 11348.9 9881.6 11386.9 11149.2 12947.3 12487.8 11473.9 3715.38 9018.4 8777.5 TRUE FALSE FALSE 10450.62259 10735.72147 11808.90853 11103.06756 12792.9119 9897.689513 11795.82675 4848.182258 8029.104083 9082.517472 1.150630607 1.182020459 1.300180106 1.222465864 1.408520484 1.089751772 1.298739781 0.533792781 0.884017466 1 13.14887652 -2.909413886 8.392535984 1.114367144 1.129718782 0 0.240090937 0 0 0.028518943 0 0.00123193 2.909413886 0.015351638 IS(ph)DAHLADTMIGK ddPTM_HeLa_Curcumin_4h_R1 2 ISDAHLADTMIGK 13 0 Q9Y657 Q9Y657 SPIN1 Spindlin-1 1 0 IS(1)DAHLADTMIGK;IS(1)DAHLADTMIGK ; 84.41 0.010818 72045000 18732.1 15564.7 16939.1 16408.6 18249.6 26562 18057.6 11650.1 18899.3 13987.7 TRUE FALSE FALSE 17249.43452 16910.04331 17566.87795 16340.70556 18031.98544 21052.74178 18564.24766 15202.16186 16826.09407 14473.77153 1.191771922 1.168323216 1.213704245 1.128987391 1.24583875 1.454544293 1.282613009 1.050324846 1.162523122 1 13.82115328 -9.327866243 0.301692133 0.889996882 1.260582163 0.139181089 0.110871602 2.960456203 0.349618221 0.389266647 0.060589048 4.70E-10 9.327866243 0.370585281 IS(ph)EDETERNGDDGTHDK ddPTM_HeLa_Curcumin_4h_R1 1 ISEDETERNGDDGTHDK 17 1 S4R3H4;E7EQT4;Q9UKV3;G3V3B0;Q9UKV3-3;Q9UKV3-2;Q9UKV3-5;G3V3T3 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 IS(0.998)EDET(0.002)ERNGDDGTHDK 70.453 0.008339 17804000 1169 1382.2 1339.6 1145.1 1526.5 1348.6 1033.8 1131.7 1366.4 1241.8 TRUE FALSE FALSE 1076.472416 1501.671209 1389.246754 1140.36188 1508.297484 1068.885158 1062.805646 1476.75012 1216.509339 1284.952458 0.83775272 1.168658965 1.08116588 0.887473986 1.17381579 0.83184802 0.827116707 1.149264404 0.946734902 1 10.32749927 IS(ph)FVEEDVHPK ddPTM_HeLa_Curcumin_4h_R1 4 ISFVEEDVHPK 11 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 0 IS(1)FVEEDVHPK;IS(1)FVEEDVHPK;IS(1)FVEEDVHPK;IS(1)FVEEDVHPK ;;; 110.15 0.0031461 36093800 21911.4 17926 21297.9 22679.3 23404.1 26584.9 27740.7 19692.2 24299.4 21655.3 TRUE FALSE FALSE 20177.08957 19475.44356 22087.21891 22585.45907 23125.02139 21070.89207 28519.02938 25696.26113 21633.81661 22407.82006 0.900448572 0.869136021 0.985692443 1.007927545 1.032006743 0.940336544 1.272726633 1.146754171 0.965458333 1 14.45171468 -4.76784654 24.99998517 0.957288111 1.209740424 0.764252638 0.054834786 49.73513584 194064.1012 0.008576841 0.026664806 1.71E-05 4.76784654 0.252452313 IS(ph)IPDVDLDLKGPK ddPTM_HeLa_Curcumin_4h_R1 1 ISIPDVDLDLKGPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 IS(1)IPDVDLDLKGPK 71.685 0.013353 19430000 5263.1 3801.6 4586.1 4768.9 4585.8 5793.4 4944.2 4316.7 5323 4312.1 TRUE FALSE FALSE 4846.520081 4130.193364 4756.0649 4749.167555 4531.11733 4591.783535 5082.920945 5632.841958 4739.080217 4461.945154 1.086189972 0.925648618 1.065917383 1.064371567 1.015502695 1.029099054 1.139171543 1.262418466 1.062110818 1 12.12345706 -4.446076828 2.246512468 1.034108436 1.279501944 0.735497983 0.043735475 0.176823812 1.340202169 0.006618954 0.07285274 3.58E-05 4.446076828 0.245393508 GIPNMLLS(ph)EEETES ddPTM_HeLa_Curcumin_4h_R1 1 GIPNMLLSEEETES 14 0 F5GYQ2;Q9UI30-2;Q9UI30 F5GYQ2 TRMT112 Multifunctional methyltransferase subunit TRM112-like protein 1 0 GIPNMLLS(0.986)EEET(0.013)ES 109.44 0.0030564 6645400 3075.8 2520.8 2269.5 2952.9 2670.4 3538 2696.3 4255.6 2719.9 2336.4 TRUE FALSE FALSE 2832.347184 2738.68672 2353.609666 2940.681682 2638.557224 2804.178919 2771.950921 5553.11285 2421.533775 2417.589726 1.171558248 1.132816991 0.973535601 1.2163692 1.091399916 1.159906864 1.146576233 2.296962462 1.001631397 1 11.23935372 -4.259645104 4.940820436 1.09492698 2.359848573 0.956528536 0.076668645 0.026033206 1.914712764 0.01142432 0.112349034 5.50E-05 4.259645104 1.264921594 up IS(ph)MPDFDLHLK ddPTM_HeLa_Curcumin_4h_R1 2 ISMPDFDLHLK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 IS(1)MPDFDLHLK;IS(1)MPDFDLHLK ; 142.38 0.00056868 14322200 11034.6 9420.4 10940.5 11075 11811.2 19151.6 16934.2 9833.1 11559.1 8478.6 TRUE FALSE FALSE 10161.19977 10234.6574 11345.96455 11029.17458 11670.35915 15179.34228 17409.32808 12831.16692 10291.09565 8773.230719 1.158205009 1.166577938 1.293248168 1.257139466 1.330223669 1.730188429 1.984369115 1.462536132 1.173010944 1 13.09889249 -5.645446347 0.794766678 1.076648874 1.803048478 0.712015841 0.151387413 0.262638735 0.290495607 0.026528615 0.111644251 2.26E-06 5.645446347 0.726399604 IS(ph)MPDLDLHLK ddPTM_HeLa_Curcumin_4h_R1 1 ISMPDLDLHLK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 IS(1)MPDLDLHLK 80.746 0.012836 4642500 4178.6 3441.4 3721.7 3332.8 4252.8 7355.8 5858.7 3444.7 5008.6 3832.6 TRUE FALSE FALSE 3847.859401 3738.859281 3859.629476 3319.009757 4202.088138 5830.124163 6023.079354 4494.973173 4459.169111 3965.782565 0.970264844 0.942779696 0.973232751 0.836911682 1.059586114 1.470106862 1.518761873 1.133439138 1.124410892 1 11.95338986 -5.368917666 4.726293363 0.971115182 1.386838729 0.704632076 0.115600614 0.073534657 2.601476516 0.014061388 0.032351945 4.28E-06 5.368917666 0.415723547 IS(ph)MPDVDLHLK ddPTM_HeLa_Curcumin_4h_R1 1 ISMPDVDLHLK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 IS(1)MPDVDLHLK 132.59 0.0010495 0 1837.4 1695 1683.9 1663.6 1799.1 1795.8 1790.6 1342.5 1494.9 1345.8 TRUE FALSE FALSE 1691.967851 1841.508247 1746.306815 1656.716464 1777.646908 1423.330837 1840.839417 1751.82207 1330.91321 1392.56645 1.214999723 1.32238447 1.254020457 1.189685752 1.276525733 1.022091863 1.321904184 1.257980953 0.955726896 1 10.44353046 -8.935167887 0.773050413 0.999634498 1.231730975 0.588575423 0.083684588 0.393693522 0.43522256 0.052284563 0.016782865 1.16E-09 8.935167887 0.232096477 IS(ph)MPDVDLHLKGPK ddPTM_HeLa_Curcumin_4h_R1 1 ISMPDVDLHLKGPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 IS(1)MPDVDLHLKGPK 86.548 0.0057378 11694000 1837.5 1250.8 1358.4 1788 1318.9 2107.2 1470.6 1559.9 1923.5 1518.2 TRUE FALSE FALSE 1692.059936 1358.913579 1408.743499 1780.60173 1303.172979 1670.142967 1511.861078 2035.506329 1712.496862 1570.957337 1.077088407 0.865022586 0.896742048 1.133450087 0.829540655 1.063137061 0.962382009 1.295710763 1.090097625 1 10.61742829 -4.255909568 24.53809262 1.007105117 1.295710924 0.456313515 0.098404921 323.9754993 1437557.225 0.012798168 0.14811565 5.55E-05 4.255909568 0.288605806 IS(ph)MSEVDLNVAAPK ddPTM_HeLa_Curcumin_4h_R1 1 ISMSEVDLNVAAPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 IS(0.987)MS(0.013)EVDLNVAAPK 268.18 3.46E-50 153420000 3117.2 2451.1 3267.5 3027 3049.5 4936.7 5235.2 2961.9 3101.1 2624.1 TRUE FALSE FALSE 2870.470331 2662.962162 3388.596424 3014.475076 3013.136704 3912.772772 5382.085622 3864.969675 2760.917089 2715.28728 1.057151614 0.980729436 1.247969764 1.110186424 1.109693522 1.441016132 1.982142244 1.423410961 1.016804781 1 11.40688913 -5.135326008 2.925189526 1.050148573 1.707042136 0.747272795 0.147998906 0.081685837 1.331596667 0.019303965 0.057478628 7.32E-06 5.135326008 0.656893563 IS(ph)PIQKPQGLDPVEILQER ddPTM_HeLa_Curcumin_4h_R1 2 ISPIQKPQGLDPVEILQER 19 1 A0A0U1RQZ9;F6VDE0;P51531-2;P51531;A0A0U1RRJ8 A0A0U1RQZ9 SMARCA2 Probable global transcription activator SNF2L2 1 0 IS(1)PIQKPQGLDPVEILQER;IS(1)PIQKPQGLDPVEILQER ; 93.342 0.0007003 234180000 2807.9 2200.6 2253.6 2419.2 2397 2764.5 2048.47 1581.81 2407.2 2004.07 TRUE FALSE FALSE 2585.651752 2390.810058 2337.120398 2409.189991 2368.417341 2191.111538 2105.944555 2064.096587 2143.136183 2073.711283 1.246871622 1.152913657 1.127023042 1.16177696 1.142115279 1.056613597 1.015543761 0.995363532 1.033478575 1 11.01799933 -5.010937557 2.670652379 1.127578856 1.004386332 0.353935024 0.064610299 0.321106765 4.537429787 0.013220325 0.045453239 9.75E-06 5.010937557 -0.123192525 IS(ph)PSSLSNNYNNMNNR ddPTM_HeLa_Curcumin_4h_R1 2 ISPSSLSNNYNNMNNR 16 0 Q9Y4E8 Q9Y4E8 USP15 Ubiquitin carboxyl-terminal hydrolase 15 1 0 IS(0.889)PS(0.095)S(0.002)LS(0.014)NNYNNMNNR;IS(0.541)PS(0.033)S(0.179)LS(0.242)NNY(0.004)NNMNNR ; 94.339 0.0051056 19773600 3557.8 3051.9 3066.5 3031.5 2885.5 4321.6 3023.9 2229.1 3588 3109.4 TRUE FALSE FALSE 3276.196376 3315.692637 3180.147188 3018.956456 2851.092297 3425.251446 3108.742496 2908.742328 3194.405377 3217.451419 1.018258227 1.030533862 0.988405658 0.938306773 0.886133752 1.064585288 0.966212723 0.90405167 0.992837175 1 11.65170265 -6.482585183 5.148103846 1.010528911 0.955629342 0.269719932 0.04546372 0.217351627 14.15000525 0.006913675 0.010451094 3.29E-07 6.482585183 -0.054899569 IS(ph)SLLEEQFQQGK ddPTM_HeLa_Curcumin_4h_R1 1 ISSLLEEQFQQGK 13 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 1 0 IS(0.655)S(0.345)LLEEQFQQGK 209.25 2.75E-09 16703000 4039.9 3634.4 3757.5 3832.8 4023.7 4591 3138.1 3301 4476.9 3992.2 TRUE FALSE FALSE 3720.137652 3948.541341 3896.756255 3816.940889 3975.720005 3638.774849 3226.14664 4307.459704 3985.795271 4130.928653 0.900557227 0.955848351 0.943312408 0.923990998 0.962427662 0.880861219 0.780973701 1.042733987 0.964866645 1 12.01225043 -9.466035977 0.776779092 1.010487466 0.918374192 0.103351749 0.064180424 1.194555074 1.039747266 0.074043226 0.011785423 3.42E-10 9.466035977 -0.092113274 IS(ph)SPTETER ddPTM_HeLa_Curcumin_4h_R1 1 ISSPTETER 9 0 P31949 P31949 S100A11 "Protein S100-A11;Protein S100-A11, N-terminally processed" 1 0 IS(0.659)S(0.34)PT(0.001)ETER 139.38 0.0024445 100520000 2110.8 2044.4 1944.9 2046.8 2105 2254.8 1954.4 2309.6 2146.2 1969.1 TRUE FALSE FALSE 1943.727953 2221.108826 2016.979705 2038.330884 2079.89925 1787.129063 2009.235204 3013.786408 1910.76723 2037.526078 0.953964699 1.090100809 0.989916019 1.000394992 1.020796382 0.877107332 0.986115086 1.479140041 0.937787864 1 10.99260281 -4.2615412 9.554675492 0.983996618 1.480708786 0.8886884 0.052569158 0.016593789 39.83796646 0.006861408 0.053242746 5.48E-05 4.2615412 0.496712168 IS(ph)TLKLTHNQDLGS(ph)SSPIS(ph)T(ph)PQFS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 ISTLKLTHNQDLGSSSPISTPQFSK 25 1 O94875-10 O94875-10 SORBS2 Sorbin and SH3 domain-containing protein 2 5 0 IS(0.767)T(0.182)LKLT(0.063)HNQDLGS(0.787)S(0.235)S(0.463)PIS(0.833)T(0.834)PQFS(0.834)K 43.611 0.013648 22024000 2688.9 3353.2 2686 2643.7 1723.1 2873.9 2892.8 2188.7 3974.9 4344.2 TRUE FALSE FALSE 2476.070728 3643.035666 2785.545523 2632.76107 1702.553158 2277.820744 2973.964182 2856.024554 3538.863415 4495.160627 0.550830311 0.810435036 0.619676526 0.585687874 0.378752463 0.50672733 0.661592417 0.635355395 0.787260725 1 12.13415695 -9.878946905 0.426973475 1.23450493 0.566856344 0.450920891 0.123168462 1.514064256 0.252217821 0.479326423 0.032572962 1.32E-10 9.878946905 -0.667648585 IS(ph)VGSDSDLVIWDPDAVK ddPTM_HeLa_Curcumin_4h_R1 2 ISVGSDSDLVIWDPDAVK 18 0 Q14195-2;Q14195;H0YBT4 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 1 0 IS(1)VGSDSDLVIWDPDAVK;IS(0.503)VGS(0.342)DS(0.155)DLVIWDPDAVK ; 200.33 2.82E-10 3541700 1509.93 1157.49 1099.29 1217.55 1562.64 1542.86 964.56 1273.54 999.81 820.1 TRUE FALSE FALSE 1390.417447 1257.538278 1140.030654 1212.512101 1544.006539 1222.853444 991.6229576 1661.836483 890.1333444 848.598414 1.638486974 1.48190034 1.343427746 1.428840875 1.819478464 1.441027257 1.168542082 1.958330885 1.048945331 1 9.728938172 -9.356939288 0.908045417 0.975641176 1.526449653 0.469471496 0.216436647 0.453475336 0.620903137 0.175823004 0.038482064 4.40E-10 9.356939288 0.550808477 IS(ph)VQPS(ph)S(ph)S(ph)LS(ph)AR ddPTM_HeLa_Curcumin_4h_R1 1 ISVQPSSSLSAR 12 0 F5H6W4;Q9H992;C9J159 F5H6W4 7-Mar E3 ubiquitin-protein ligase MARCH7 5 0 IS(1)VQPS(1)S(1)S(1)LS(1)AR 71.529 0.0080583 4643100 55.666 0 0 0 107.06 179.15 0 57.323 69.097 0 TRUE FALSE FALSE 51.25997736 0 0 0 105.7833794 141.9922706 0 74.80051882 61.51723197 0 0 IS(ph)WLS(ph)S(ph)LDWEAK ddPTM_HeLa_Curcumin_4h_R1 1 ISWLSSLDWEAK 12 0 K7EKE8;Q92692-2;Q92692 K7EKE8 PVRL2 Nectin-2 3 0 IS(1)WLS(1)S(1)LDWEAK 57.328 0.019769 9067700 2743.9 2279.2 2425.2 2331 2461.9 2854.7 2540.1 2107.3 2885.5 2294.8 TRUE FALSE FALSE 2526.71742 2476.203892 2515.080045 2321.35494 2432.54345 2262.603041 2611.36837 2749.806069 2568.967869 2374.544129 1.064085265 1.042812328 1.059184378 0.977600252 1.024425455 0.952857861 1.099734613 1.158035362 1.081878344 1 11.21343485 ISAAASDS(ph)GVESFDEGSSH ddPTM_HeLa_Curcumin_4h_R1 2 ISAAASDSGVESFDEGSSH 19 0 A0A2R8Y4W2;A0A2R8YE63;Q12929-2;Q12929 A0A2R8Y4W2 EPS8 Epidermal growth factor receptor kinase substrate 8 1 0 ISAAAS(0.032)DS(0.968)GVESFDEGSSH;ISAAAS(0.005)DS(0.995)GVES(0.001)FDEGSSH ; 177.39 2.84E-22 2925300 2211.3 1286.82 1696.94 1186.97 1789.84 2532.42 1737.99 739.17 1932.57 1144.89 TRUE FALSE FALSE 2036.273272 1398.046987 1759.830089 1182.058633 1768.497327 2007.167546 1786.753322 964.5395303 1720.571906 1184.674842 1.718845711 1.180110303 1.485496295 0.997791622 1.492812427 1.694277176 1.508222559 0.814180816 1.452357934 1 10.21027542 -9.652299782 1.502864727 1.000838355 1.421767523 0 0.311997133 0.484130825 1.972903432 0.200868095 0.0457241 2.23E-10 9.652299782 0.420929169 ISAAASDSGVES(ph)FDEGSSH ddPTM_HeLa_Curcumin_4h_R1 1 ISAAASDSGVESFDEGSSH 19 0 A0A2R8Y4W2;A0A2R8YE63;Q12929-2;Q12929 A0A2R8Y4W2 EPS8 Epidermal growth factor receptor kinase substrate 8 1 0 ISAAASDSGVES(1)FDEGSSH 262.24 4.92E-55 4063400 860.08 888.37 592.19 679.19 974.57 1239.2 927.85 367.49 992.83 871.72 TRUE FALSE FALSE 792.0037604 965.1567443 614.1370823 676.3796917 962.9488893 982.1759513 953.8829738 479.5360093 883.9190329 902.0122051 0.878041069 1.070004085 0.680852298 0.749856474 1.067556385 1.08887213 1.057505617 0.53162918 0.979941322 1 9.817003144 -9.402976493 0.846720216 1.007832513 0.900403122 0.044065574 0.180152229 2.391811339 2.685605283 0.177775227 0.033877942 3.95E-10 9.402976493 -0.107429391 ISAPELLLHS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 2 ISAPELLLHSPAR 13 0 Q5VUA4 Q5VUA4 ZNF318 Zinc finger protein 318 1 0 ISAPELLLHS(1)PAR;IS(0.003)APELLLHS(0.997)PAR ; 135.79 0.00059766 8248500 11061.7 9998.9 9449.2 10152.8 9565.1 10335 7418.2 4057 11179.1 9564.7 TRUE FALSE FALSE 10186.15477 10863.16036 9799.395664 10110.7904 9451.04243 8191.404501 7626.334727 5293.960624 9952.780699 9897.072613 1.029208855 1.097613485 0.990130723 1.021594041 0.95493312 0.827659331 0.770564694 0.534901665 1.005628744 1 13.27278615 -4.237964533 0.793150449 1.021985839 0.244329918 0.953022964 0.034455816 0.374938023 0.164159888 0.005721077 0.258960955 5.78E-05 4.237964533 -0.777655921 ISASS(ph)ATR ddPTM_HeLa_Curcumin_4h_R1 1 ISASSATR 8 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-3;A0A1B0GU60;A0A1B0GV30;P49023-4 A0A1B0GTU4;P49023-4 PXN Paxillin 1 0 IS(0.337)AS(0.055)S(0.608)ATR 109.44 0.011459 79071000 2686.2 2396.7 2447.8 2708 2562.1 3268.3 3003 819.48 2791.1 2558.4 TRUE FALSE FALSE 2473.584436 2603.860069 2538.517621 2696.795014 2531.548631 2590.417739 3087.256098 1069.33568 2484.923313 2647.30421 0.934378613 0.98358929 0.958906654 1.018694793 0.956274168 0.978511547 1.166188641 0.403933812 0.938661792 1 11.37030827 -4.249942241 24.99998206 0.981688112 0.403933471 0.883481447 0.064041641 404.4969515 879543.5915 0.008341029 0.178346756 5.62E-05 4.249942241 -0.577754641 ISDEDWDIIHR ddPTM_HeLa_Curcumin_4h_R1 2 ISDEDWDIIHR 11 0 E7ER27;A0A2R8YD50;P51659-3;P51659;P51659-2;A0A2R8YDT8;A0A2R8YF45 E7ER27 HSD17B4 Peroxisomal multifunctional enzyme type 2;(3R)-hydroxyacyl-CoA dehydrogenase;Enoyl-CoA hydratase 2 0 0 ; ; 172.17 0.00018193 42152000 17492 13819.1 16115.9 15026.4 15919.2 17350.9 12032.1 10152.8 16148.1 14625.2 FALSE FALSE TRUE 16107.48974 15013.56143 16713.16943 14964.22474 15729.37394 13752.12776 12369.68834 13248.34198 14376.69383 15133.42461 1.064365149 0.992079573 1.104387795 0.988819459 1.039379674 0.908725428 0.817375357 0.87543582 0.949996065 1 13.88545088 -5.118209833 3.108055111 1.031357353 0.847239451 0.719781819 0.044209001 0.076555077 1.394736982 0.005249748 0.015502888 7.62E-06 5.118209833 -0.184117902 ISDS(ph)ES(ph)EDPPR ddPTM_HeLa_Curcumin_4h_R1 1 ISDSESEDPPR 11 0 Q96ST2-3;Q96ST2;B8ZZB6 Q96ST2-3 IWS1 Protein IWS1 homolog 2 0 IS(0.324)DS(0.903)ES(0.773)EDPPR 122.69 0.0091867 15684000 2546.3 2517 2778.1 2310.5 3106.1 2808.7 2609.4 2464.3 2190.7 2380 TRUE FALSE FALSE 2344.757668 2734.558264 2881.05883 2300.939763 3069.061786 2226.143959 2682.612741 3215.653726 1950.385691 2462.704823 0.952106662 1.110388155 1.169875822 0.934314069 1.246215851 0.903942664 1.089295281 1.305740621 0.791968925 1 11.266028 -1.603726233 1.109967554 1.009554397 139.5760901 0.315126605 0.127360596 552.0966645 1.913223686 0.015883599 193708.4557 0.024904267 1.603726233 138.5665357 ISDSEGFK ddPTM_HeLa_Curcumin_4h_R1 1 ISDSEGFK 8 0 P23246;P23246-2 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 0 118.74 0.0028618 5651400 4803.8 4012.1 4957.3 4573.7 4841.1 5812.8 5176.7 4445.7 5517.9 4526.5 FALSE FALSE TRUE 4423.574161 4358.888046 5141.021899 4554.775241 4783.373044 4607.159756 5321.94427 5801.173465 4912.600175 4683.795538 0.9444422 0.930631581 1.09761877 0.972453901 1.021260003 0.983638103 1.136246069 1.23856249 1.048850262 1 12.19346238 -4.554618064 2.058592896 0.9816032 1.252021924 0.702974014 0.049592848 0.145424835 0.994981608 0.006588035 0.058374279 2.79E-05 4.554618064 0.270418725 ISDYFEYQGGNGSS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 2 ISDYFEYQGGNGSSPVR 17 0 C9JWT6;B3KRP1;Q9UKI8-4;Q9UKI8-5;Q9UKI8;Q9UKI8-2 C9JWT6 TLK1 Serine/threonine-protein kinase tousled-like 1 1 0 ISDYFEYQGGNGS(0.008)S(0.992)PVR;IS(0.012)DY(0.019)FEY(0.318)QGGNGS(0.108)S(0.543)PVR ; 276.62 1.54E-65 152773000 9090.2 7122 7383.6 8195 8210.7 9004.5 7367.7 5511 8732 7836.4 TRUE FALSE FALSE 8370.701078 7737.593945 7657.242711 8161.091261 8112.792765 7136.865198 7574.417833 7191.27853 7774.121446 8108.714317 1.032309285 0.954231909 0.944322665 1.00645934 1.000502971 0.88014757 0.93410836 0.886858046 0.958736631 1 12.98525747 -4.918430851 0.478448267 1.01329869 0.846781916 0.394414221 0.03756689 1.394750501 0.317798244 0.00837279 0.116690836 1.21E-05 4.918430851 -0.166516774 ISEENLLEEVEK ddPTM_HeLa_Curcumin_4h_R1 1 ISEENLLEEVEK 12 0 Q5VXJ5;A0A087WZC3;Q15431 Q5VXJ5 SYCP1 Synaptonemal complex protein 1 0 0 48.44 0.019836 5835700 1372.7 1033.3 1194.3 1062.7 1277.5 1350.3 1077.4 854.91 1508.8 1074.5 FALSE FALSE TRUE 1264.049347 1122.613848 1238.561809 1058.302829 1262.266647 1070.232559 1107.628944 1115.568123 1343.288415 1111.838795 1.136899839 1.0096912 1.113976068 0.951849165 1.135296459 0.962578895 0.996213614 1.003354199 1.208168325 1 10.11873191 -5.233269636 24.90051915 1.061002934 0.988265369 0.218989487 0.074137116 857.9467803 758377.4834 0.009064619 0.023105092 5.84E-06 5.233269636 -0.072737565 ISFPGS(ph)SESPLSSK ddPTM_HeLa_Curcumin_4h_R1 1 ISFPGSSESPLSSK 14 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 0 ISFPGS(0.551)S(0.325)ES(0.123)PLS(0.001)SK 186.29 4.00E-05 39429000 3581 2548.4 3062.1 3353.4 3022.6 2799.4 3154.7 1150.3 3629.7 2803.5 TRUE FALSE FALSE 3297.560071 2768.672341 3175.58412 3339.524519 2986.557469 2218.772884 3243.212392 1501.021175 3231.530991 2900.921416 1.136728507 0.954411355 1.094681194 1.15119441 1.029520294 0.764851082 1.117993881 0.517429106 1.113967091 1 11.5022955 -4.004973776 2.390901107 1.0483855 3.48E-22 0.644879845 0.114181685 0.976837042 3.073996618 0.015906363 2.827446089 9.89E-05 4.004973776 -1.0483855 VGPCSS(ph)PPAAR ddPTM_HeLa_Curcumin_4h_R1 2 VGPCSSPPAAR 11 0 Q8TDM6-4;Q8TDM6;A0A0A0MSL1;Q8TDM6-2;A0A0J9YYG8 Q8TDM6-4 DLG5 Disks large homolog 5 1 0 VGPCS(0.054)S(0.946)PPAAR;VGPCS(0.298)S(0.702)PPAAR ; 96.756 0.01307 54642000 4804.5 4291.9 4914.5 4645.6 4374 5116.7 2727.1 985.51 4960.4 4119.4 TRUE FALSE FALSE 4424.218755 4662.872712 5096.635693 4626.377738 4321.842907 4055.438743 2803.615086 1285.987462 4416.25653 4262.548843 1.03792799 1.093916547 1.195677957 1.085354774 1.013910471 0.951411677 0.657732073 0.301694481 1.036060041 1 12.05750065 -4.444713441 1.525379444 1.043746672 0.156695258 0.951418074 0.055113841 0.13999843 0.387324557 0.00965414 0.166891027 3.59E-05 4.444713441 -0.887051414 down ISGLIYEETR ddPTM_HeLa_Curcumin_4h_R1 1 ISGLIYEETR 10 0 P62805 P62805 HIST1H4A Histone H4 0 0 91.584 0.019324 3278500 1240.4 753.19 991.9 1233.4 778.97 1986.1 1239.8 984.03 1023.8 1074.3 FALSE FALSE TRUE 1142.221031 818.2923875 1028.660687 1228.296518 769.6812915 1574.160472 1274.585451 1284.056217 911.4917014 1111.631845 1.027517371 0.736118159 0.925360938 1.10494902 0.692388667 1.416080764 1.146589545 1.155109241 0.819958249 1 10.11846335 -5.247857757 24.99923591 0.973811363 1.229992797 0.469117874 0.151550237 600.1574495 1104687.174 0.019512922 0.049453322 5.65E-06 5.247857757 0.256181434 S(ph)LEGGGCPAR ddPTM_HeLa_Curcumin_4h_R1 2 SLEGGGCPAR 10 0 Q9Y613 Q9Y613 FHOD1 FH1/FH2 domain-containing protein 1 1 0 S(1)LEGGGCPAR;S(1)LEGGGCPAR ; 121.29 0.0043436 256450000 1671.54 1697.13 1575.42 1929.51 1733.72 1839.8 1263.72 667.43 1849.14 1703.65 TRUE FALSE FALSE 1539.235845 1843.822355 1633.806451 1921.526199 1713.046521 1458.204741 1299.176582 870.9263345 1646.293968 1762.851711 0.873151063 1.045931625 0.926797439 1.090010117 0.971747374 0.827185141 0.7369744 0.494044014 0.933881142 1 10.78369541 -4.444467998 1.34768555 0.958467449 0.39493854 0.849376686 0.06386711 0.303185399 0.607566796 0.010786249 0.21123349 3.59E-05 4.444467998 -0.563528909 down ISHSLYSGIEGLDES(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 ISHSLYSGIEGLDESPSR 18 0 F5GZI3;B1AP52;Q5VWV2;Q8TEW0-4;Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-3;Q8TEW0-7;Q8TEW0-6;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 F5GZI3;Q5VWV2 PARD3 Partitioning defective 3 homolog 1 0 ISHSLYSGIEGLDES(0.815)PS(0.185)R;ISHSLYSGIEGLDES(0.997)PS(0.003)R ; 211.45 6.99E-13 9624800 3124.38 2743.76 2462.14 2972.63 3100.93 3126.5 2393.83 1250.85 2900.63 2616.9 TRUE FALSE FALSE 2877.082026 2980.918388 2553.389074 2960.330045 3063.953435 2478.028657 2460.994427 1632.228407 2582.438146 2707.83708 1.062501894 1.1008485 0.942962593 1.093245257 1.131513213 0.915132109 0.908841394 0.602779399 0.95369037 1 11.40292522 -4.053969217 1.253413286 1.03812336 0.236787384 0.795023016 0.065677425 0.645550244 0.61019713 0.008820485 0.751150567 8.83E-05 4.053969217 -0.801335976 ISICSSDK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 ISICSSDKR 9 1 Q13547 Q13547 HDAC1 Histone deacetylase 1 0 1 ; ISICSSDK(1)R;ISICSSDK(1)R 117.81 0.00051209 11793400 8208.5 4460.7 7063.3 4400.4 5425.1 8940.1 3875.5 2816.6 5723.5 6148.7 FALSE TRUE FALSE 7558.788563 4846.263032 7325.072112 4382.192311 5360.409226 7085.822484 3984.2361 3675.368374 5095.646369 6362.366867 1.188046638 0.761707574 1.151312438 0.688767624 0.842518097 1.113708567 0.62621917 0.577673129 0.800904204 1 12.63534785 -3.718588892 0.384621044 1.078046832 1.40E-12 0.189682591 0.191234312 5.746690097 0.428827942 0.048466939 3.111721461 0.000191166 3.718588892 -1.078046832 ISINQT(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 2 ISINQTPGK 9 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424;H0YDG6 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 IS(0.001)INQT(0.999)PGK;ISINQT(1)PGK ; 144.7 0.0059823 540516000 22010.8 19608.5 20920.7 19730.6 19874.1 24582.6 18901.6 14689.4 19399.7 17259 TRUE FALSE FALSE 20268.62195 21303.37137 21696.03955 19648.96001 19637.11434 19483.89166 19431.92802 19168.13044 17271.60145 17858.74897 1.134940751 1.192881506 1.214868947 1.100242802 1.099579504 1.090999806 1.088090104 1.073318768 0.967122696 1 14.1243434 -9.125631728 0.968496661 1.002613201 1.124840619 0.587747918 0.046072615 0.366417772 0.638182343 0.029428683 0.00932001 7.49E-10 9.125631728 0.122227418 ISIVEPGY(ph)FRT(ph)GMTNMT(ph)QSLERMK ddPTM_HeLa_Curcumin_4h_R1 1 ISIVEPGYFRTGMTNMTQSLERMK 24 2 O14756 O14756 HSD17B6 17-beta-hydroxysteroid dehydrogenase type 6 3 0 IS(0.021)IVEPGY(0.97)FRT(0.503)GMT(0.505)NMT(0.5)QS(0.5)LERMK 44.105 0.0075626 0 201.12 222.95 226.55 275.54 334.2 375.83 265.85 354.48 244.25 372.86 TRUE FALSE FALSE 185.2011398 242.2208046 234.9461423 274.3998885 330.2148833 297.8786215 273.3090355 462.5593202 217.4563861 385.8168572 0.480023452 0.627812912 0.60895769 0.711217987 0.855885058 0.772072593 0.708390601 1.198909046 0.563625933 1 8.591772369 -4.259393138 23.87738422 0.734489642 1.198909352 0.504058076 0.144552227 89.91499655 1049055.056 0.027336978 0.238308567 5.50E-05 4.259393138 0.46441971 ISLEQPPNGS(ph)DTPNPEK ddPTM_HeLa_Curcumin_4h_R1 2 ISLEQPPNGSDTPNPEK 17 0 Q9UHI6;E9PJ60 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 1 0 ISLEQPPNGS(0.5)DT(0.5)PNPEK;ISLEQPPNGS(0.635)DT(0.365)PNPEK ; 197.94 5.51E-08 19130700 7390.7 5902.9 6712.7 5612.1 7020.7 7408 6879.6 3529.8 6169.1 6002.1 TRUE FALSE FALSE 6805.718296 6413.120373 6961.478567 5588.878617 6936.982738 5871.497295 7072.623061 4606.019771 5492.365164 6210.672528 1.095810199 1.032596767 1.120889652 0.899882998 1.116945501 0.945388324 1.138785378 0.741629791 0.884343063 1 12.60053379 -4.250034527 24.92768213 1.043395877 0.741629606 0.464721554 0.089866738 822.2872466 1797246.221 0.009396867 0.197563782 5.62E-05 4.250034527 -0.301766271 ISLSAPAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 ISLSAPAKK 9 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 0 1 ISLSAPAK(1)K 128.36 0.0002418 5080900 3675 3613 3457.8 2865.6 3382.3 4801.2 2407.5 2826.3 3424.2 2975.7 FALSE TRUE FALSE 3384.119872 3925.291621 3585.94911 2853.742906 3341.968282 3805.376999 2475.047971 3688.025859 3048.573827 3079.105354 1.099059462 1.274815627 1.164607475 0.926809115 1.085369904 1.235870996 0.803820489 1.197758906 0.990084286 1 11.58829552 -3.940986778 22.23044831 1.063645216 3.947972494 0.08075628 0.134858853 1815.747558 734424.5881 0.017344395 18844.65654 0.000114555 3.940986778 2.884327277 ISMPDFDLHLK ddPTM_HeLa_Curcumin_4h_R1 1 ISMPDFDLHLK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 89.356 0.014478 19006000 5585.3 5032 5378.4 5105.6 5834.4 6991.9 5671.3 5525.2 5706.5 4856.9 FALSE FALSE TRUE 5143.217611 5466.943658 5577.728235 5084.47438 5764.828591 5541.701125 5830.421414 7209.808045 5080.511227 5025.676913 1.023388033 1.08780245 1.109846162 1.011699412 1.147075049 1.102677554 1.160126589 1.434594418 1.010910831 1 12.29510221 -1 0.535419902 1.021019185 16.66542295 0.857532682 0.046052472 27.8746751 0.243026463 0.008728457 500.9845147 0.1 1 15.64440376 ISMPDIDLNLT(ph)GPK ddPTM_HeLa_Curcumin_4h_R1 1 ISMPDIDLNLTGPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 ISMPDIDLNLT(1)GPK 153.94 0.011228 29781000 3353.1 2388.4 3162.4 3237 3066 4842.9 4313.2 1812.8 2670.9 1930.6 TRUE FALSE FALSE 3087.698597 2594.842653 3279.601326 3223.606152 3029.439952 3838.427949 4434.216784 2365.514375 2377.908952 1997.688206 1.545635894 1.298922747 1.641698297 1.61366831 1.516472862 1.921434955 2.219674106 1.184125915 1.190330375 1 10.96411571 -10.69602608 0.172121884 0.060551209 1.887182932 0.391732333 0.271882215 13.02732305 0.365650407 5.377352848 0.530018744 2.01E-11 10.69602608 1.826631723 ISMPDLDLHLKS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 ISMPDLDLHLKSPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 ISMPDLDLHLKS(1)PK;ISMPDLDLHLKS(1)PK;ISMPDLDLHLKS(1)PK;ISMPDLDLHLKS(1)PK ;;; 81.494 0.0077537 1373503800 20103.1 15430.4 16660.9 18198.6 18047.3 19587.3 17714.3 26384.9 19859.7 16992.8 TRUE FALSE FALSE 18511.91842 16764.13502 17278.36761 18123.29902 17832.09773 15524.67319 18211.31558 34429.53455 17681.1406 17583.29854 1.05281261 0.953412409 0.982657923 1.030710989 1.014149746 0.882921549 1.03571668 1.958081669 1.005564488 1 14.10191812 -4.262142108 6.121324123 1.007716196 1.981648714 0.974467358 0.046734701 0.014338653 2.723333755 0.006851365 0.057886431 5.47E-05 4.262142108 0.973932518 ISMPDVDLHLK ddPTM_HeLa_Curcumin_4h_R1 4 ISMPDVDLHLK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ;;; ;;; 150.46 0.00047957 45503000 13392.7 11819.9 13101.5 13138.1 14816.8 16828.6 12770.2 13595.9 13850.5 11570 FALSE FALSE TRUE 12332.65366 12841.55949 13587.05312 13083.73802 14640.11934 13338.15866 13128.49744 17741.22732 12331.1348 11972.05664 1.03011989 1.072627693 1.134897163 1.092856342 1.222857507 1.114107548 1.096594999 1.481886351 1.029993022 1 13.54738339 -1 0.330352866 1.012162933 4.696444609 0.664045967 0.076748117 21.81071774 0.276812663 0.023594139 49.75584527 0.1 1 3.684281677 ISMPDVDLHLK(ac)GPK ddPTM_HeLa_Curcumin_4h_R1 1 ISMPDVDLHLKGPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 1 ISMPDVDLHLK(1)GPK 73.36 0.0099233 1605000 1548 1437.9 1281.8 1372.9 1871.7 2512.8 1972.5 1910.7 2959.8 1445.7 FALSE TRUE FALSE 1425.474167 1562.185669 1329.304636 1367.219304 1849.3812 1991.616955 2027.843041 2493.263634 2635.117345 1495.937967 0.952896576 1.044285059 0.888609464 0.913954544 1.236268642 1.331349961 1.355566264 1.666689187 1.761515118 1 10.54683464 -4.922760257 0.913880429 0.970223888 1.675733809 0.214707459 0.262532401 0.223477222 0.247549185 0.012755415 0.124459423 1.19E-05 4.922760257 0.705509921 ISMQDVDLS(ph)LGSPK ddPTM_HeLa_Curcumin_4h_R1 3 ISMQDVDLSLGSPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 ISMQDVDLS(0.996)LGS(0.003)PK;ISMQDVDLS(1)LGSPK;ISMQDVDLS(0.89)LGS(0.11)PK ;; 218.2 6.93E-14 241474000 13119.1 11553.3 11938.3 11481.2 11458.7 18410.1 18755.7 9336.9 14180.1 10387.7 TRUE FALSE FALSE 12080.70939 12551.91577 12380.7439 11433.69384 11322.06249 14591.63774 19281.93446 12183.67783 12624.57851 10748.6718 1.123925785 1.167764353 1.151839421 1.063730854 1.053345259 1.357529377 1.793889963 1.133505428 1.174524512 1 13.39187078 -5.145978323 4.184685277 1.075627051 1.485652063 0.458974825 0.159762804 0.116716004 3.440254414 0.020341611 0.055087866 7.15E-06 5.145978323 0.410025013 ISMQDVDLSLGS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 ISMQDVDLSLGSPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 ISMQDVDLS(0.083)LGS(0.917)PK;ISMQDVDLS(0.068)LGS(0.932)PK;ISMQDVDLS(0.226)LGS(0.774)PK;ISMQDVDLS(0.005)LGS(0.995)PK ;;; 193.47 5.49E-06 1056998000 13206.9 10366.9 10759.5 12542.5 11362 17328.9 17226.4 8156.4 13269.3 9254.6 TRUE FALSE FALSE 12161.55993 11262.96864 11158.25654 12490.60246 11226.51557 13734.6908 17709.72642 10643.24881 11813.69099 9576.196661 1.269978088 1.176142162 1.165207538 1.304338549 1.172335528 1.43425321 1.849348656 1.111427552 1.233651668 1 13.22523707 -1.000000265 0.045403373 0.25813145 3.099728444 0.180309468 0.200916316 414.3283435 1.440939712 23.06805505 86.22665123 0.099999939 1.000000265 2.841596994 ISMS(ph)EVDLNVAAPK ddPTM_HeLa_Curcumin_4h_R1 1 ISMSEVDLNVAAPK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 IS(0.25)MS(0.75)EVDLNVAAPK 207.08 3.26E-09 140980000 3200.3 2808 2185.1 3410.6 3174.8 4832.9 4760.7 2806.9 2767.7 2785.3 TRUE FALSE FALSE 2946.992878 3050.711008 2266.081728 3396.487841 3136.942584 3830.502062 4894.272429 3662.710889 2464.090234 2882.088968 1.022519746 1.058506882 0.786263628 1.178481261 1.0884267 1.329071415 1.698168406 1.270852819 0.854966749 1 11.49289916 -5.247087618 2.075655963 1.007699607 1.492681803 0.672942747 0.141674866 0.123329244 1.018924188 0.017504073 0.054626954 5.66E-06 5.247087618 0.484982195 ISNLS(ph)PEEEQGLWK ddPTM_HeLa_Curcumin_4h_R1 2 ISNLSPEEEQGLWK 14 0 F5GX09;Q5HYJ3-3;Q5HYJ3-2;Q5HYJ3 F5GX09 FAM76B Protein FAM76B 1 0 ISNLS(1)PEEEQGLWK;ISNLS(1)PEEEQGLWK ; 279.19 3.96E-63 212360000 15989.6 12791.4 13569.1 13929.4 13844.8 15898.1 13872.8 10940 15425.9 12112.5 TRUE FALSE FALSE 14724.00629 13897.03162 14071.98278 13871.76383 13679.7098 12600.65485 14262.03343 14275.55564 13733.71736 12533.40847 1.174780693 1.108799067 1.122757853 1.106783032 1.091459664 1.00536537 1.137921377 1.13900027 1.095768752 1 13.61349119 -9.538441373 1.311282339 1.000222265 1.115965138 0.091241042 0.050631162 0.317852223 0.981829427 0.032429507 0.007783944 2.89E-10 9.538441373 0.115742873 ISQQQEQLLMKS(ph)PTVPVPGSK ddPTM_HeLa_Curcumin_4h_R1 1 ISQQQEQLLMKSPTVPVPGSK 21 1 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 0 IS(0.001)QQQEQLLMKS(0.843)PT(0.154)VPVPGS(0.002)K 50.556 0.013666 15430000 1353.5 1169.1 1437.6 1394.5 1275.9 1770.5 1630.1 1739.1 1627.6 1271.1 TRUE FALSE FALSE 1246.369047 1270.151795 1490.878721 1388.729928 1260.685726 1403.278342 1675.836219 2269.343584 1449.056352 1315.27063 0.94761414 0.965696158 1.133514796 1.05585109 0.958499108 1.066912246 1.274137946 1.725381478 1.101717258 1 10.36114396 -4.1804648 1.356688994 0.989774559 2.145874479 0.914946387 0.064663701 0.261882468 0.36381379 0.008718135 0.435456681 6.60E-05 4.1804648 1.156099919 ISQRDPS(ph)PESNK ddPTM_HeLa_Curcumin_4h_R1 1 ISQRDPSPESNK 12 1 E7EX82;Q8NDX5-2;Q8NDX5;Q8NDX5-7;Q8NDX5-3 E7EX82 PHC3 Polyhomeotic-like protein 3 1 0 IS(0.001)QRDPS(0.986)PES(0.013)NK 154.72 0.0034355 26964000 4579.5 3906.3 3732.6 3964.3 4558.4 4300.9 3572.2 1568.9 4204.1 3627.4 TRUE FALSE FALSE 4217.027743 4243.943166 3870.93344 3947.896777 4504.044057 3408.844859 3672.426318 2047.250388 3742.920748 3753.45188 1.123506542 1.130677388 1.031299605 1.051804287 1.199973838 0.908189306 0.978413054 0.545431366 0.997194281 1 11.87400227 -3.972679529 1.37435597 1.067528655 1.14E-17 0.803917241 0.075590899 0.794068835 0.784165452 0.010983964 1.41736142 0.000106493 3.972679529 -1.067528655 ISQVCSLK(ac)TYK(ac)RK ddPTM_HeLa_Curcumin_4h_R1 1 ISQVCSLKTYKRK 13 3 H7BXQ9;A0A590UJ07;Q5T890 H7BXQ9 ERCC6L2 DNA excision repair protein ERCC-6-like 2 0 2 ISQVCSLK(1)TYK(1)RK 59.185 0.019218 0 436.63 511.98 448.48 378.53 600.68 1104.4 249.68 464.12 449.94 451.38 FALSE TRUE FALSE 402.0702748 556.2332699 465.1010633 376.9637432 593.5172833 875.3349908 256.6853488 605.6280515 400.5827077 467.0654214 0.860843591 1.190910833 0.995794255 0.807089812 1.270736938 1.874116453 0.549570439 1.296666428 0.857658669 1 8.867480831 -5.746736237 24.93059269 0.951318217 1.242639919 0.175971422 0.313421212 313.4386518 531462.1692 0.043054299 0.085813407 1.79E-06 5.746736237 0.291321702 ISREPEPAAGPQAEESATVSAPAPMS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 5 ISREPEPAAGPQAEESATVSAPAPMSPTR 29 1 Q9BWG6-2;Q9BWG6 Q9BWG6-2 SCNM1 Sodium channel modifier 1 1 0 ISREPEPAAGPQAEESATVSAPAPMS(0.726)PT(0.274)R;ISREPEPAAGPQAEES(0.007)AT(0.035)VS(0.114)APAPMS(0.664)PT(0.18)R;ISREPEPAAGPQAEESATVSAPAPMS(0.994)PT(0.006)R;ISREPEPAAGPQAEESATVSAPAPMS(0.961)PT(0.039)R;ISREPEPAAGPQAEESATVSAPAPMS(0.971)PT(0.029)R ;;;; 159.92 1.01E-13 376292000 10051.64 7578.01 8549.9 8367.84 8703.47 12603.5 8150.21 6203.97 10689.2 9069 TRUE FALSE FALSE 9256.042088 8233.019417 8866.766815 8333.216095 8599.686805 9989.392029 8378.882957 8095.531893 9516.621503 9384.147075 0.986348787 0.877332735 0.944866565 0.888009963 0.9164058 1.064496533 0.892876347 0.862681694 1.014116832 1 13.19600991 -7.401093849 7.383565203 0.994007434 0.924939581 0.310059166 0.053784612 0.264371441 14.95762264 0.009092894 0.010365333 3.97E-08 7.401093849 -0.069067853 ISREPEPAAGPQAEESATVSAPAPMSPT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 ISREPEPAAGPQAEESATVSAPAPMSPTR 29 1 Q9BWG6-2;Q9BWG6 Q9BWG6-2 SCNM1 Sodium channel modifier 1 1 0 ISREPEPAAGPQAEESATVSAPAPMS(0.388)PT(0.612)R 137.19 4.75E-12 95652000 1902.9 1563.3 1527.9 1754.1 1959.3 2749.3 1643.8 1452.1 2588.3 1860.4 TRUE FALSE FALSE 1752.283457 1698.424686 1584.525318 1746.841999 1935.936627 2179.064189 1689.920604 1894.838605 2304.369966 1925.048762 0.910254063 0.88227619 0.823109185 0.907427403 1.005655891 1.131952724 0.877858596 0.98430681 1.197044985 1 10.91067927 -5.748019615 24.74416944 0.936008268 1.000652405 0.027145503 0.110435005 350.2681151 645840.6997 0.011917296 0.023724771 1.79E-06 5.748019615 0.064644137 ISRPGDS(ph)DDSR ddPTM_HeLa_Curcumin_4h_R1 1 ISRPGDSDDSR 11 1 P14866;M0QXS5;A0A3B3ITJ4;P14866-2;B4DVF8;M0R1W6;M0QYL7 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 1 0 IS(0.001)RPGDS(0.831)DDS(0.168)R 65.565 0.019965 15054000 3194.4 2867.2 2938.1 2904.5 3177 4140 3139.3 3310.2 2905.6 2993.8 TRUE FALSE FALSE 2941.559869 3115.027992 3046.988571 2892.481949 3139.11635 3281.317333 3227.380309 4319.464742 2586.862949 3097.834327 0.949553643 1.005550221 0.983586677 0.933710987 1.013326091 1.059229444 1.041818241 1.394349822 0.835055292 1 11.59704428 -1.3801495 1.023085264 0.97799579 200 0.840568968 0.055142097 134.1107939 0.379151003 0.004980387 62315.01294 0.041672591 1.3801495 199.0220042 ISRPGDSDDS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 ISRPGDSDDSR 11 1 P14866;M0QXS5;A0A3B3ITJ4;P14866-2;B4DVF8;M0R1W6;M0QYL7 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 1 0 ISRPGDS(0.253)DDS(0.747)R 174.72 0.0020298 10889000 2799.4 2787.6 2369 2675.6 2817.3 3494.9 2830.3 2482.5 2412.5 2265.7 TRUE FALSE FALSE 2577.824536 3028.547723 2456.797224 2664.529076 2783.705538 2770.018344 2909.710601 3239.402822 2147.854786 2344.432906 1.099551422 1.291803964 1.047928144 1.136534583 1.187368395 1.181530227 1.241114895 1.381742601 0.9161511 1 11.19502328 -1 0.127740972 0.943254929 2.162823655 0.664610432 0.076569725 38.41097228 0.332430063 0.253500932 8.446619592 0.1 1 1.219568726 ISRPGDSDDSR ddPTM_HeLa_Curcumin_4h_R1 4 ISRPGDSDDSR 11 1 P14866;M0QXS5;A0A3B3ITJ4;P14866-2;B4DVF8;M0R1W6;M0QYL7 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 0 ;;; ;;; 101.3 0.0088817 88330600 13521 11398.4 12506.4 10977.9 12470 14711.7 12090 10877.2 12352.2 10801.6 FALSE FALSE TRUE 12450.79858 12383.62691 12969.89819 10932.47636 12321.30339 11660.32758 12429.21286 14193.60821 10997.19456 11176.9548 1.113970559 1.107960722 1.160414301 0.978126561 1.102384649 1.043247271 1.112039289 1.269899402 0.983916887 1 13.44823955 ISS(ph)KSPGHMVILDQTK ddPTM_HeLa_Curcumin_4h_R1 1 ISSKSPGHMVILDQTK 16 1 Q9NWH9;Q9NWH9-3 Q9NWH9 SLTM SAFB-like transcription modulator 1 0 IS(0.17)S(0.708)KS(0.121)PGHMVILDQTK 75.224 0.0078824 119560000 4728.5 2729.1 2729.1 3410.3 4590.8 7720.5 4364.6 1187.1 6079.5 3710.9 TRUE FALSE FALSE 4354.234236 2964.991243 2830.242847 3396.189082 4536.057708 6119.181272 4487.058929 1549.041325 5412.59406 3839.853499 1.133958428 0.772162595 0.737070528 0.884457983 1.181310097 1.593597588 1.168549511 0.403411569 1.409583481 1 11.90683555 -4.255526631 24.54914152 1.059854926 0.403411197 0.389272493 0.257012038 415.5137385 1725106.082 0.03402521 0.407270042 5.55E-05 4.255526631 -0.656443729 ISS(ph)LLEEQFQQGK ddPTM_HeLa_Curcumin_4h_R1 1 ISSLLEEQFQQGK 13 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 1 0 IS(0.004)S(0.996)LLEEQFQQGK 209.11 2.85E-09 18764000 2840.4 2372.7 2443.5 3066.8 2605.4 3462.1 2580.7 2195.9 3053.9 2712.6 TRUE FALSE FALSE 2615.579343 2577.785615 2534.05826 3054.110394 2574.332307 2744.021434 2653.107496 2865.419801 2718.89481 2806.862648 0.931851562 0.918386804 0.902808073 1.08808687 0.917156494 0.977611582 0.945221704 1.020862137 0.968659728 1 11.45474275 ISS(ph)PTETER ddPTM_HeLa_Curcumin_4h_R1 2 ISSPTETER 9 0 P31949 P31949 S100A11 "Protein S100-A11;Protein S100-A11, N-terminally processed" 1 0 IS(0.004)S(0.993)PT(0.003)ETER;IS(0.02)S(0.977)PT(0.003)ETER ; 134.84 0.0031576 107848000 7554.9 6057.4 6797.4 7427.9 7045.9 7992.8 6566.6 7372.4 7977.8 6349.9 TRUE FALSE FALSE 6956.921693 6580.974665 7049.317624 7397.165318 6961.882244 6335.003183 6750.841123 9620.210822 7102.655299 6570.558552 1.058802176 1.00158527 1.072864288 1.125804642 1.059557142 0.964149871 1.027437937 1.464138969 1.080981966 1 12.6818003 -4.260913532 24.98015116 1.033943293 1.464139101 0.885185064 0.045335034 10.00168375 474993.7794 0.006401755 0.050921308 5.48E-05 4.260913532 0.430195807 ISSIQSIVPALEIANAHR ddPTM_HeLa_Curcumin_4h_R1 3 ISSIQSIVPALEIANAHR 18 0 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 ;; ;; 105.02 0.00082223 15853580 3295.64 3089.78 2685.927 2446.85 3122.13 12375.22 6120.76 4874.1 3884.53 2766.26 FALSE FALSE TRUE 3034.786616 3356.846815 2785.469817 2436.725583 3084.900639 9808.459875 6292.492052 6360.190652 3458.406778 2862.387329 1.060229196 1.172743738 0.973128196 0.851291353 1.077736967 3.426671078 2.198337027 2.221988124 1.208224597 1 11.48300319 -5.287462482 22.34084993 1.025114827 2.573932049 0.825839387 0.329389383 49.25552705 42285.87557 0.042636776 0.09539274 5.16E-06 5.287462482 1.548817222 ISSKRY(ph)T(ph)WT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 ISSKRYTWTK 10 2 Q75NE6 Q75NE6 MIR17HG Putative microRNA 17 host gene protein 3 0 IS(0.001)S(0.003)KRY(0.999)T(0.999)WT(0.998)K 64.42 0.015095 4248100 1459.7 1021 1250.6 1182.1 1247.9 1785.6 1305.2 1426.3 1537.7 1266 TRUE FALSE FALSE 1344.163205 1109.250691 1296.948336 1177.208783 1233.019608 1415.246432 1341.820399 1861.172304 1369.018157 1309.993406 1.026083947 0.846760515 0.990041881 0.898637183 0.94124108 1.080346226 1.024295537 1.420749369 1.045057289 1 10.35534383 -3.746489035 1.504246779 0.987803438 2.471828934 0.796492397 0.066397232 1.573215171 1.107066914 0.00964376 5.106038103 0.000179271 3.746489035 1.484025496 NLS(ph)GSTLYPVSNIPR ddPTM_HeLa_Curcumin_4h_R1 2 NLSGSTLYPVSNIPR 15 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 0 NLS(0.934)GS(0.062)T(0.004)LYPVSNIPR;NLS(0.932)GS(0.065)T(0.003)LYPVSNIPR ; 120.63 0.0012761 110322000 2535.37 2238.96 2225.5 2199.13 1944.31 2056.98 1573.84 668.86 2438.44 2790.8 TRUE FALSE FALSE 2334.692789 2432.485726 2307.978988 2190.030583 1921.125373 1630.339161 1617.997715 872.7923349 2170.949233 2887.780092 0.808473192 0.842337591 0.799222556 0.758378586 0.665260273 0.564564859 0.56029118 0.302236426 0.751770967 1 11.49574517 -4.442713519 0.29413086 0.964426985 6.92E-24 0.811629968 0.07943418 1.447303292 0.100813889 0.028722479 0.495548839 3.61E-05 4.442713519 -0.964426985 down ISSPTETER ddPTM_HeLa_Curcumin_4h_R1 3 ISSPTETER 9 0 P31949 P31949 S100A11 "Protein S100-A11;Protein S100-A11, N-terminally processed" 0 0 ;; ;; 180.87 2.20E-16 81570000 6449.9 4588.39 5555.1 5741.1 6054.9 7276.1 5559.83 5486.3 6092.8 4998.9 FALSE FALSE TRUE 5939.383609 4984.989986 5760.976893 5717.344849 5982.699272 5766.954841 5715.823866 7159.047614 5424.435083 5172.611403 1.148236963 0.963727912 1.113746316 1.10531111 1.156611005 1.114902008 1.105017064 1.384029662 1.048684052 1 12.3366771 -1.21431068 1.011903816 1.073671955 200 0.696291374 0.059330678 545.1581863 1.086590943 0.010544081 250984.8749 0.061050513 1.21431068 198.926328 ISST(ph)PPSGSR ddPTM_HeLa_Curcumin_4h_R1 2 ISSTPPSGSR 10 0 Q3Y452 Q3Y452 TDRG1 Testis development-related protein 1 1 0 IS(0.008)S(0.224)T(0.767)PPSGS(0.001)R;IS(0.037)S(0.216)T(0.744)PPS(0.003)GSR ; 121.29 0.012592 2026280000 9647.3 7476.3 7357 8071.7 8566.5 9617.6 7908.6 7755.6 9330.1 7677.3 TRUE FALSE FALSE 8883.706025 8122.518058 7629.656892 8038.301444 8464.350082 7622.801347 8130.494031 10120.24674 8306.611373 7944.085604 1.118279242 1.022461044 0.960419773 1.011859872 1.065490795 0.959556798 1.023465058 1.273934754 1.045634676 1 12.95566545 -4.259282697 24.79820079 1.037976242 1.273934845 0.712937647 0.046908898 94.57696614 1087390.207 0.008163746 0.072238466 5.50E-05 4.259282697 0.235958603 ISTPS(ph)FSS(ph)Y(ph)Y(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 ISTPSFSSYYK 11 0 Q9Y5T4 Q9Y5T4 DNAJC15 DnaJ homolog subfamily C member 15 4 0 IST(0.068)PS(0.88)FS(0.549)S(0.903)Y(0.8)Y(0.8)K 58.246 0.0084126 0 663.9 357.27 663.82 689.66 771.02 529.73 933.6 745.29 776.41 470.17 TRUE FALSE FALSE 611.3516145 388.1508268 688.4217532 686.8063697 761.8260901 419.8580267 959.7943033 972.5254901 691.2397655 486.5083725 1.256610675 0.797829696 1.4150255 1.411705139 1.565905405 0.863002675 1.972821759 1.998990244 1.420817821 1 8.926320823 -1 0.406794042 1.100997248 17.68869156 0.447546069 0.291485295 35.69608241 0.417159223 0.063078128 482.2043879 0.1 1 16.58769431 ISTVVSSK ddPTM_HeLa_Curcumin_4h_R1 1 ISTVVSSK 8 0 H0YLA2;P37108 H0YLA2 SRP14 Signal recognition particle 14 kDa protein 0 0 136.27 0.0010556 2821100 2246.6 1811.2 1777.6 1917.6 1952.2 2271.6 2029 2049.5 2397 2157.2 FALSE FALSE TRUE 2068.779239 1967.752057 1843.47942 1909.665479 1928.92129 1800.444554 2085.928279 2674.383115 2134.055097 2232.162539 0.926804927 0.881545149 0.825871498 0.855522591 0.864149118 0.806592048 0.934487629 1.198113071 0.956048253 1 11.12422637 -8.421857297 0.955759593 0.990281792 0.901769104 0.052034936 0.104654714 0.835572117 1.577709718 0.036594924 0.021796692 3.79E-09 8.421857297 -0.088512688 ISVSS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 1 ISVSSPGR 8 0 O75864-2;O75864 O75864-2 PPP1R37 Protein phosphatase 1 regulatory subunit 37 1 0 IS(0.002)VS(0.084)S(0.915)PGR 93.143 0.019066 27523000 8363.3 6851.2 7051.6 6983.3 7219 8204.1 5417 3098.8 8023 6833.9 TRUE FALSE FALSE 7701.33598 7443.3872 7312.938499 6954.404955 7132.91814 6502.477181 5568.986441 4043.609855 7142.896973 7071.377516 1.089085678 1.05260781 1.034160386 0.983458306 1.008702777 0.919548867 0.787539122 0.571827744 1.010113936 1 12.78777557 -3.993949505 0.805479597 1.042623971 0.093283675 0.967513935 0.026598883 0.529284495 0.186005208 0.005728957 0.495193699 0.000101403 3.993949505 -0.949340296 ISVYYNEATGGK ddPTM_HeLa_Curcumin_4h_R1 2 ISVYYNEATGGK 12 0 Q5JP53;P07437 Q5JP53 TUBB Tubulin beta chain 0 0 ; ; 229.68 2.47E-38 16504300 5946.1 4381.5 4910.4 4965.4 4438.5 6076.8 4871 4335.4 5080.7 4874.3 FALSE FALSE TRUE 5475.459911 4760.217336 5092.383744 4944.85449 4385.573786 4816.40318 5007.66715 5657.243502 4523.359921 5043.681562 1.085607773 0.943798152 1.009656078 0.980405767 0.869518373 0.954937999 0.992859499 1.121649619 0.896836937 1 12.30026148 -7.255207416 24.92717692 1.040425893 0.977917469 0 0.077221578 664.9459246 2659710.756 0.01119886 0.013530228 5.56E-08 7.255207416 -0.062508424 ISYIPDEEVS(ph)SPSPPQR ddPTM_HeLa_Curcumin_4h_R1 2 ISYIPDEEVSSPSPPQR 17 0 F8W930;Q9Y6M1-5;Q9Y6M1-6;Q9Y6M1-3;Q9Y6M1-4;Q9Y6M1-1;Q9Y6M1 F8W930 IGF2BP2 Insulin-like growth factor 2 mRNA-binding protein 2 1 0 ISYIPDEEVS(0.5)S(0.5)PSPPQR;ISYIPDEEVS(0.333)S(0.333)PS(0.333)PPQR ; 169.94 6.86E-05 27250000 6220.8 4141.3 4705.3 4675.9 5679.2 6129.3 5418.9 5849.3 5089.2 4396.1 TRUE FALSE FALSE 5728.417116 4499.255519 4879.682557 4656.552365 5611.479249 4858.014089 5570.93975 7632.724643 4530.927493 4548.864148 1.259307143 0.989094282 1.072725498 1.02367365 1.233600096 1.067962008 1.224688091 1.677940777 0.996056894 1 12.15129063 -4.266380962 2.719772596 1.109793496 1.784699522 0.781229863 0.093987045 0.18328196 1.811190418 0.015221305 0.275453219 5.42E-05 4.266380962 0.674906026 ISYIPDEEVSS(ph)PSPPQR ddPTM_HeLa_Curcumin_4h_R1 1 ISYIPDEEVSSPSPPQR 17 0 F8W930;Q9Y6M1-5;Q9Y6M1-6;Q9Y6M1-3;Q9Y6M1-4;Q9Y6M1-1;Q9Y6M1 F8W930 IGF2BP2 Insulin-like growth factor 2 mRNA-binding protein 2 1 0 ISYIPDEEVS(0.023)S(0.975)PS(0.002)PPQR 305.9 2.39E-95 24386000 2770.1 2585.3 2661.5 3369.2 2945.6 3136.6 2693.9 2529.8 2346 2659.3 TRUE FALSE FALSE 2550.843662 2808.761812 2760.137531 3355.259143 2910.475644 2486.033803 2769.483584 3301.124374 2088.649669 2751.710477 0.927002925 1.020733044 1.003062479 1.219335817 1.057696901 0.903450354 1.00645893 1.199662683 0.759036856 1 11.42611297 -6.802446429 2.551310125 0.966406885 1.064011478 0.261935555 0.109873963 0.349443571 4.666509211 0.015111232 0.021026119 1.58E-07 6.802446429 0.097604593 ISYT(ph)PPES(ph)PVPSYASSTPLHVPVPR ddPTM_HeLa_Curcumin_4h_R1 2 ISYTPPESPVPSYASSTPLHVPVPR 25 0 P41212 P41212 ETV6 Transcription factor ETV6 2 0 IS(0.093)Y(0.135)T(0.854)PPES(0.887)PVPS(0.014)Y(0.015)AS(0.002)STPLHVPVPR;IS(0.091)Y(0.057)T(0.857)PPES(0.987)PVPS(0.005)Y(0.001)ASSTPLHVPVPR ; 72.514 0.00059582 49958000 1953.17 1627.69 1261.31 1547.22 2007.69 2601.34 1705.02 734.1 2628.61 1507.53 TRUE FALSE FALSE 1798.574534 1768.380271 1308.055258 1540.818014 1983.749608 2061.792761 1752.858272 957.9237106 2340.258059 1559.916555 1.152994067 1.133637735 0.838541814 0.98775669 1.271702388 1.321732726 1.123687204 0.614086508 1.500245671 1 10.60725314 -9.728668845 1.659426825 1.000111699 1.081917234 0 0.252264923 1.615529895 8.055532721 0.141405635 0.03100381 1.87E-10 9.728668845 0.081805535 ISYT(ph)PPESPVPSYASSTPLHVPVPR ddPTM_HeLa_Curcumin_4h_R1 1 ISYTPPESPVPSYASSTPLHVPVPR 25 0 P41212 P41212 ETV6 Transcription factor ETV6 1 0 IS(0.059)Y(0.005)T(0.928)PPES(0.008)PVPSYASSTPLHVPVPR 118.44 2.43E-08 19626000 1086.9 813.28 863.71 577.17 910.24 1533.2 943.03 342.19 1018 706.81 TRUE FALSE FALSE 1000.870718 883.5762993 895.7198524 574.7818235 899.3859825 1215.197037 969.4888838 446.5221558 906.3279469 731.3715949 1.368484537 1.20810858 1.224712388 0.785895744 1.229725066 1.661531629 1.325576343 0.610527068 1.239216772 1 9.514460786 -9.649188511 1.503566285 1.000656968 1.216732488 0 0.289572862 0.924083832 3.774937405 0.196444165 0.044987681 2.24E-10 9.649188511 0.216075519 IT(ph)KTES(ph)LVIPS(ph)T(ph)RS(ph)EGK ddPTM_HeLa_Curcumin_4h_R1 1 ITKTESLVIPSTRSEGK 17 2 F8VW41;Q86VP3-4;Q86VP3;Q86VP3-3;Q86VP3-2 F8VW41 PACS2 Phosphofurin acidic cluster sorting protein 2 5 0 IT(0.625)KT(0.625)ES(0.751)LVIPS(0.999)T(1)RS(1)EGK 47.217 0.0095392 0 948.53 1903.7 943.54 1046.3 1310.7 1816.9 1747 1721.7 970.65 641.24 TRUE FALSE FALSE 873.4528496 2068.247345 978.5084224 1041.970688 1295.070759 1440.054459 1796.016118 2246.638404 864.1721234 663.5230423 1.316386612 3.117069361 1.474716566 1.570360969 1.951809773 2.170315675 2.706787864 3.385923715 1.302399568 1 9.374002757 -1 0.175217879 0.831436918 10.49638951 0.539184139 0.530794148 28.94940566 0.309525682 0.737310182 74.36807083 0.1 1 9.664952592 IT(ph)LY(ph)DY(ph)QAMCR ddPTM_HeLa_Curcumin_4h_R1 1 ITLYDYQAMCR 11 0 Q8IZS8-2;Q8IZS8 Q8IZS8-2 CACNA2D3 Voltage-dependent calcium channel subunit alpha-2/delta-3;Voltage-dependent calcium channel subunit alpha-2-3;Voltage-dependent calcium channel subunit delta-3 3 0 IT(1)LY(1)DY(1)QAMCR 61.691 0.0095661 0 0 0 185.23 257.81 124.58 130.08 0 0 131.73 220.99 TRUE FALSE FALSE 0 0 192.0947867 256.7432505 123.0944649 103.0999417 0 0 117.2795486 228.6693861 0 0 0.840054675 1.122770542 0.538307585 0.450869019 0 0 0.512878224 1 7.837119422 -9.547987771 1.338080801 0.997273753 0.344402527 0.084548552 0.397833739 0.494829021 1.597654133 0.288175905 0.06952222 2.83E-10 9.547987771 -0.652871226 IT(ph)PPAAKPGS(ph)PQAK ddPTM_HeLa_Curcumin_4h_R1 1 ITPPAAKPGSPQAK 14 1 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3;A0A0A0MSW3;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 0 IT(1)PPAAKPGS(1)PQAK 127.49 0.0049744 5195200 2882.8 2523.3 2702.6 2704.7 3000 3143.4 2450.5 1746.5 2675.1 2373.6 TRUE FALSE FALSE 2654.623338 2741.402808 2802.760733 2693.508668 2964.226959 2491.423407 2519.254435 2278.99981 2381.648223 2456.082423 1.080836422 1.116168897 1.141150927 1.09666868 1.206892298 1.014389168 1.02572064 0.927900378 0.969693932 1 11.26214326 -4.328284144 1.845637622 1.066918033 0.898126416 0.315595751 0.066961781 0.785394359 3.012100056 0.010156618 0.217484969 4.70E-05 4.328284144 -0.168791617 IT(ph)PSYVAFTPEGER ddPTM_HeLa_Curcumin_4h_R1 1 ITPSYVAFTPEGER 14 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 1 0 IT(0.513)PS(0.486)YVAFTPEGER 128.96 0.0032644 3314700 555.17 626.54 523.01 635.68 658.36 675.33 506.26 293.51 633.71 497.48 TRUE FALSE FALSE 511.2277087 680.6953258 542.3932107 633.0497246 650.509487 535.2589455 520.4642931 382.9998478 564.1935985 514.767393 0.993123721 1.322335748 1.053666604 1.229778213 1.263695984 1.039807402 1.01106694 0.744025074 1.096016582 1 9.007776861 -4.244031289 2.706913255 1.061647809 0.67446124 0.408280863 0.121341961 0.461467149 4.304683672 0.019296941 0.406223923 5.70E-05 4.244031289 -0.387186569 IT(ph)TSKGIHFQDYDT(ph)TPFQAKTQ ddPTM_HeLa_Curcumin_4h_R1 1 ITTSKGIHFQDYDTTPFQAKTQ 22 2 P15428-3;P15428-5;P15428 P15428-3 HPGD 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 2 0 IT(0.717)T(0.141)S(0.141)KGIHFQDY(0.028)DT(0.483)T(0.483)PFQAKT(0.006)Q 49.34 0.0093153 0 1367.1 1201.3 1198.3 1130 739.56 1555.2 1119.3 983.46 1132.1 1071.4 TRUE FALSE FALSE 1258.892592 1305.135019 1242.710052 1125.324359 730.74123 1232.633989 1150.704546 1283.312427 1007.911462 1108.63107 1.135537896 1.177249181 1.120941029 1.015057569 0.659138328 1.111852286 1.037950835 1.157564911 0.909149571 1 10.11456363 -6.011958822 24.92504927 1.079293495 0.98271992 0.057985945 0.143084282 1055.462153 2199841.655 0.02065472 0.035538299 9.73E-07 6.011958822 -0.096573575 IT(ph)VNYPPY(ph)IS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 ITVNYPPYISK 11 0 Q14982-3;Q14982-2;Q14982;Q14982-4 Q14982-3 OPCML Opioid-binding protein/cell adhesion molecule 3 0 IT(0.999)VNY(0.052)PPY(0.962)IS(0.988)K 76.827 0.018133 34136000 2425.1 3397.8 4123.8 3402.2 2394.5 3253.5 3408.1 2417.5 3125.1 4807.5 TRUE FALSE FALSE 2233.150776 3691.490692 4276.631656 3388.122598 2365.947151 2578.687425 3503.722114 3154.584621 2782.284349 4974.560267 0.448914207 0.74207377 0.859700441 0.681089868 0.475609305 0.518374949 0.704328006 0.634143412 0.559302571 1 12.28035329 -9.503144749 1.218828301 1.002467656 0.618023258 0 0.17983403 0.302768571 0.796658773 0.098232722 0.023161055 3.14E-10 9.503144749 -0.384444398 ITAASK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 ITAASKK 7 1 P50914 P50914 RPL14 60S ribosomal protein L14 0 1 ; ITAASK(1)K;ITAASK(1)K 98.458 0.007706 5723400 8888.2 5942.4 6765.9 4730.8 5361.2 8042 4487.3 2667 5289.4 7599.5 FALSE TRUE FALSE 8184.689591 6456.034577 7016.650206 4711.225203 5297.271192 6373.998548 4613.201561 3480.156023 4709.166053 7863.582059 1.040834766 0.821004286 0.89229694 0.599119481 0.673646075 0.810571887 0.586653961 0.44256625 0.598857622 1 12.94097093 -6.552944637 0.941263534 1.022981309 0.609679562 0.210840595 0.165852516 0.183350719 0.324520014 0.018970362 0.034069743 2.80E-07 6.552944637 -0.413301747 ITADGAHFELR ddPTM_HeLa_Curcumin_4h_R1 1 ITADGAHFELR 11 0 J3QK89;Q8IWX8 J3QK89 CHERP Calcium homeostasis endoplasmic reticulum protein 0 0 110.64 0.0033578 0 2218.9 1787.8 2112.7 2317.9 2201.6 2679.4 2132.2 1673.1 2516 2353.7 FALSE FALSE TRUE 2043.271724 1942.329466 2190.998521 2308.309144 2175.347358 2123.662237 2192.023793 2183.220488 2240.001095 2435.4909 0.83895683 0.797510459 0.89961269 0.947779827 0.893186404 0.87196476 0.900033662 0.89641907 0.919732894 1 11.24999688 -9.397661337 1.145677282 0.999420601 0.878222508 0.275946119 0.044725137 0.300625325 0.711041547 0.028543527 0.00742442 4.00E-10 9.397661337 -0.121198093 ITAHSS(ph)PPLTK ddPTM_HeLa_Curcumin_4h_R1 2 ITAHSSPPLTK 11 0 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 0 ITAHS(0.095)S(0.905)PPLTK;ITAHS(0.225)S(0.775)PPLTK ; 155.88 0.00042657 61761000 7626.2 5587.5 5966.3 5908.6 6102 8142.4 6299.1 2273.8 7409.2 5649.3 TRUE FALSE FALSE 7022.578223 6070.458603 6187.416326 5884.151779 6029.237635 6453.574456 6475.835793 2967.071153 6596.429297 5845.612755 1.201341676 1.038464034 1.058471812 1.006592812 1.031412426 1.104003075 1.107811288 0.507572307 1.128441033 1 12.51313854 -4.259846155 24.78945848 1.081722683 0.507572092 0.892343504 0.059105396 37.36622327 581330.5267 0.01103361 0.093952672 5.50E-05 4.259846155 -0.57415059 ITDLYTDLRDGR ddPTM_HeLa_Curcumin_4h_R1 1 ITDLYTDLRDGR 12 1 A0A087WUZ3;Q01082;Q01082-2;F8W6C1;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 98.182 0.0088961 20231000 3452.2 2517.4 2384.3 2848.8 2226.6 3366.6 2463.6 2440.9 4138.3 3331.8 FALSE FALSE TRUE 3178.954727 2734.992839 2472.664255 2837.01242 2200.049249 2668.329211 2532.721986 3185.119173 3684.338844 3447.579802 0.922083 0.793308058 0.71721741 0.82289971 0.638143096 0.773971703 0.734637668 0.923871051 1.068673984 1 11.75136823 -7.366520611 1.773951821 0.97172796 0.761557364 0.640275091 0.077139084 0.151686 0.912005753 0.013092344 0.014921839 4.30E-08 7.366520611 -0.210170595 ITEAPAS(ph)EKEIVEVKEENIEDATEK ddPTM_HeLa_Curcumin_4h_R1 1 ITEAPASEKEIVEVKEENIEDATEK 25 2 Q5JSL0;Q5JSK6;P82970;Q5JSK9 Q5JSL0 HMGN5 High mobility group nucleosome-binding domain-containing protein 5 1 0 IT(0.012)EAPAS(0.985)EKEIVEVKEENIEDAT(0.003)EK 44.683 0.011937 10838000 2388.2 1637.5 1971.9 1752 1899.9 2046.8 2336.1 2073.6 1761.6 1437.3 TRUE FALSE FALSE 2199.17145 1779.038203 2044.980349 1744.750688 1877.244933 1622.270608 2401.644679 2705.831094 1568.356887 1487.246068 1.478687016 1.196196273 1.375011434 1.173141907 1.262228876 1.090788298 1.614826713 1.819356697 1.054537592 1 10.53842765 -11.60552209 0.358770412 4.98E-15 1.392652435 0.315930053 0.207316395 13.64028619 0.617630943 9.961131743 0.071942571 2.48E-12 11.60552209 1.392652435 ITEFCHR ddPTM_HeLa_Curcumin_4h_R1 3 ITEFCHR 7 0 P07237;H7BZ94;I3L398;H0Y3Z3 P07237 P4HB Protein disulfide-isomerase 0 0 ;; ;; 167.82 0.007705 23811600 10168.2 8129.8 9769.3 8158.9 9371.9 9855.2 6398.12 4039.23 8718.9 8785.8 FALSE FALSE TRUE 9363.376241 8832.503686 10131.35885 8125.140634 9260.146213 7811.120429 6577.634028 5270.772633 7762.458484 9091.105896 1.02994909 0.971554373 1.114425348 0.893746121 1.018594032 0.859204647 0.72352408 0.579772438 0.853851949 1 13.15024009 -4.599157424 1.054791867 1.01441955 0.481941598 0.769701478 0.072680288 0.221507756 0.277663658 0.007090527 0.114938903 2.52E-05 4.599157424 -0.532477952 ITEK(ac)LEK ddPTM_HeLa_Curcumin_4h_R1 2 ITEKLEK 7 1 P51532;P51532-4;P51532-3;P51532-2;P51532-5;A0A0A0MT49;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8Y440;A0A2R8Y4C5;A0A2R8YGP5 P51532 SMARCA4 Transcription activator BRG1 0 1 ; ITEK(1)LEK;ITEK(1)LEK 112.84 0.011818 28792000 15791 12855.9 15085.5 14939.6 14531.2 17647.1 16927.9 12755.1 16706.9 14076.9 FALSE TRUE FALSE 14541.12569 13967.10671 15644.5819 14877.78389 14357.92493 13986.89254 17402.85131 16644.07127 14874.19487 14566.07123 0.998287422 0.958879474 1.074042661 1.021399914 0.985710196 0.960237824 1.194752589 1.142660297 1.021153517 1 13.83032418 -4.758568278 24.99999935 1.000178855 1.168706494 0.797506608 0.033491544 20.40565456 177671.4929 0.00434038 0.01492088 1.74E-05 4.758568278 0.168527639 ITES(ph)EEVVSR ddPTM_HeLa_Curcumin_4h_R1 2 ITESEEVVSR 10 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 IT(0.027)ES(0.973)EEVVSR;IT(0.048)ES(0.952)EEVVSR ; 99.343 0.013013 10303200 2578.5 2374.2 2346.2 3062.7 2786 3196.9 2441 1518.5 3190 2806.1 TRUE FALSE FALSE 2374.409004 2579.415269 2433.152236 3050.027359 2752.77877 2533.826904 2509.48789 1981.48366 2840.064981 2903.611766 0.817743278 0.888347161 0.837974368 1.050425334 0.948053318 0.872646589 0.864264266 0.682420316 0.978114572 1 11.50363285 -9.484934533 1.211167262 1.000413614 0.871844797 0.222962441 0.088498981 0.596768892 1.558352197 0.064000029 0.015430973 3.27E-10 9.484934533 -0.128568817 ITES(ph)SLVEITEHK ddPTM_HeLa_Curcumin_4h_R1 2 ITESSLVEITEHK 13 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 0 IT(0.117)ES(0.517)S(0.366)LVEITEHK;IT(0.12)ES(0.875)S(0.006)LVEITEHK ; 165.86 6.73E-10 4507800 5355.3 5393.6 6187.5 6343.5 7457.3 8195.7 9083.2 3980 5239.2 4830.4 TRUE FALSE FALSE 4931.422354 5859.798751 6416.814193 6317.252278 7368.376568 6495.819435 9338.050146 5193.483678 4664.472868 4998.25604 0.986628599 1.172368663 1.283810621 1.263891291 1.474189499 1.299617183 1.868261664 1.039059151 0.933220073 1 12.28720909 -6.639645421 0.979339368 0.987745565 1.443718992 0.460168855 0.196579013 0.281587892 0.539816801 0.033729697 0.056762646 2.29E-07 6.639645421 0.455973428 ITESEEVVSR ddPTM_HeLa_Curcumin_4h_R1 4 ITESEEVVSR 10 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ;;; ;;; 218.58 2.59E-34 104012000 9109.4 7822.4 8177.7 7875.9 8687.5 10015.3 8162.3 7443 9404.4 8070.7 FALSE FALSE TRUE 8388.381378 8498.5334 8480.772756 7843.311613 8583.907236 7938.013884 8391.31217 9712.336437 8372.760849 8351.156224 1.004457485 1.017647518 1.015520789 0.939188707 1.027870513 0.950528726 1.00480843 1.162993025 1.002587022 1 13.02776024 -4.26348958 5.91291741 0.99812491 1.167526636 0.773165291 0.027157232 0.042007227 6.794622793 0.003392189 0.02858736 5.45E-05 4.26348958 0.169401726 ITITNDK ddPTM_HeLa_Curcumin_4h_R1 2 ITITNDK 7 0 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65;E9PM13;A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;Q53FA3;P34931;P17066;P54652 P11142;A0A0G2JIW1;P17066;P54652 HSPA8;HSPA1B;HSPA1A;HSPA1L;HSPA6;HSPA2 Heat shock cognate 71 kDa protein;Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 1-like;Heat shock 70 kDa protein 6;Heat shock-related 70 kDa protein 2 0 0 ; ; 107.29 0.015673 28021000 11209.9 7890.8 10569.5 9325.3 11590.2 11211.4 10304 9464.8 8163.8 8526.9 FALSE FALSE TRUE 10322.62459 8572.845591 10961.21497 9286.714379 11451.99443 8886.029261 10593.10251 12350.57395 7268.251565 8823.20914 1.169939919 0.971624434 1.242316123 1.052532501 1.297939814 1.007119872 1.200595196 1.399782523 0.823765078 1 13.10708777 -1 0.10221592 0.947657664 1.851044065 0.380432181 0.130586519 114.7244116 0.833059851 0.83325284 14.61557823 0.1 1 0.9033864 ITITNDK(ac)GR ddPTM_HeLa_Curcumin_4h_R1 1 ITITNDKGR 9 1 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65;E9PM13;A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;Q53FA3;P34931;P17066;P54652 P11142;A0A0G2JIW1;P17066;P54652 HSPA8;HSPA1B;HSPA1A;HSPA1L;HSPA6;HSPA2 Heat shock cognate 71 kDa protein;Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 1-like;Heat shock 70 kDa protein 6;Heat shock-related 70 kDa protein 2 0 1 ITITNDK(1)GR 114.89 0.0019884 11527000 2792.8 2474.9 2232.8 2144.7 3442.4 4925.8 3048.6 3144.6 4660.9 2532.3 FALSE TRUE FALSE 2571.746933 2688.819328 2315.549532 2135.8258 3401.351628 3904.133555 3134.135511 4103.374064 4149.610931 2620.297237 0.981471452 1.026150503 0.883697277 0.815108214 1.298078547 1.489958277 1.196099232 1.565995646 1.583641303 1 11.35551476 -5.624865144 5.647720093 0.974580441 1.394822426 0.340569465 0.220672064 0.066665511 3.142848054 0.01456141 0.029452565 2.37E-06 5.624865144 0.420241985 ITITNDKGR ddPTM_HeLa_Curcumin_4h_R1 2 ITITNDKGR 9 1 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65;E9PM13;A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;Q53FA3;P34931;P17066;P54652 P11142;A0A0G2JIW1;P17066;P54652 HSPA8;HSPA1B;HSPA1A;HSPA1L;HSPA6;HSPA2 Heat shock cognate 71 kDa protein;Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 1-like;Heat shock 70 kDa protein 6;Heat shock-related 70 kDa protein 2 0 0 ; ; 104.42 0.0026054 25215000 6923.6 6072.8 5079.9 5540.6 5399.8 4899.2 4202.9 3582.8 7060.4 7335.2 FALSE FALSE TRUE 6375.589754 6597.705772 5268.165563 5517.674465 5335.410912 3883.050695 4320.822062 4675.179227 6285.891784 7590.097654 0.839987843 0.869251764 0.694084029 0.72695698 0.702943645 0.5115943 0.569270945 0.615957718 0.82817008 1 12.88990273 -6.435324869 0.306923066 1.009253562 0.470111898 0.752200597 0.07079517 0.460846622 0.096232184 0.037735902 0.092280561 3.67E-07 6.435324869 -0.539141663 ITKPGS(ph)IDSNNQLFAPGGR ddPTM_HeLa_Curcumin_4h_R1 2 ITKPGSIDSNNQLFAPGGR 19 1 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 0 IT(0.27)KPGS(0.686)IDS(0.045)NNQLFAPGGR;IT(0.07)KPGS(0.927)IDS(0.003)NNQLFAPGGR ; 70.767 0.0042879 73876000 2157.91 1604.54 1535.4 1959.08 1504.46 4843.8 6530.8 2193.8 2105.41 1778.78 TRUE FALSE FALSE 1987.109146 1743.229288 1592.303275 1950.973846 1486.520297 3839.141279 6714.036671 2862.679521 1874.45179 1840.592473 1.079602995 0.947102259 0.865103655 1.059970567 0.807631412 2.085818201 3.64775841 1.555303286 1.01839588 1 10.84595452 -5.107581471 4.275666839 1.009031747 2.657600398 0.665539783 0.480826874 0.081857043 2.50809857 0.058391115 0.159474498 7.81E-06 5.107581471 1.648568652 ITKPGSIDSNNQLFAPGGR ddPTM_HeLa_Curcumin_4h_R1 1 ITKPGSIDSNNQLFAPGGR 19 1 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 0 0 119.04 1.13E-05 1891000 1131.2 920.69 1155.4 973.96 1029.7 1221.4 1148 840.49 1317.9 1395.8 FALSE FALSE TRUE 1041.664326 1000.270341 1198.22014 969.9300116 1017.4215 968.067872 1180.20979 1096.751532 1173.329667 1444.303946 0.721222378 0.692562216 0.829617716 0.671555329 0.70443725 0.67026603 0.817147799 0.759363384 0.812384173 1 10.49615867 -9.188112544 0.719406378 1.01953561 0.730262331 0.351333656 0.077608519 0.290549487 0.244088813 0.050348502 0.011138842 6.48E-10 9.188112544 -0.28927328 ITKPGSIDSNNQLFAPGGRLS(ph)WGK ddPTM_HeLa_Curcumin_4h_R1 3 ITKPGSIDSNNQLFAPGGRLSWGK 24 2 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 0 ITKPGSIDSNNQLFAPGGRLS(1)WGK;ITKPGSIDS(0.001)NNQLFAPGGRLS(0.999)WGK;ITKPGSIDSNNQLFAPGGRLS(1)WGK ;; 94.031 2.68E-05 349033000 5074 3955.1 4657.2 4434.6 3612.71 5787.8 4480.4 2222.91 5136 5063.3 TRUE FALSE FALSE 4672.387546 4296.96122 4829.799929 4416.2508 3569.630793 4587.345038 4606.107966 2900.665026 4572.59365 5239.249298 0.891804776 0.820148265 0.921849611 0.842916714 0.68132486 0.875572964 0.879154189 0.553641345 0.87275741 1 12.3551444 -1.350774412 0.105927896 1.095695429 1.25E-13 0.378575124 0.095272881 60.32220267 0.486927631 0.587974606 9.620296547 0.04458878 1.350774412 -1.095695429 ITLDNAYMEK ddPTM_HeLa_Curcumin_4h_R1 3 ITLDNAYMEK 10 0 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ;; ;; 149.33 6.36E-06 88254000 14023.07 10029.01 11953.4 11017.72 11870.15 16561.98 12500.5 11162.46 11808.49 10913.08 FALSE FALSE TRUE 12913.12921 10895.87294 12396.40352 10972.13159 11728.60621 13126.83866 12851.23039 14565.84267 10513.12819 11292.30872 1.143533137 0.964893292 1.097774054 0.971646443 1.038636696 1.162458359 1.138051634 1.289890582 0.930999006 1 13.46305286 -4.263411571 1.088692488 1.055845308 1.394166839 0.558620105 0.07077654 1.075500007 1.004008566 0.010453377 0.417864091 5.45E-05 4.263411571 0.338321531 ITLPVDFVTADKFDENAK ddPTM_HeLa_Curcumin_4h_R1 4 ITLPVDFVTADKFDENAK 18 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 0 ;;; ;;; 213.69 6.37E-17 144579240 12111.02 8288.04 10229.89 10562.59 8993.89 10807.47 9387.34 9859.6 9913.72 9225.966 FALSE FALSE TRUE 11152.41999 9004.421247 10609.01872 10518.8848 8886.643736 8565.878897 9650.723496 12865.74665 8826.209719 9546.567632 1.168212536 0.943210334 1.111291422 1.101849922 0.930873176 0.897273159 1.010910294 1.347682973 0.924542732 1 13.22076641 ITLQDVVSHSK ddPTM_HeLa_Curcumin_4h_R1 2 ITLQDVVSHSK 11 0 P46940;H0YLE8;A0A0J9YXZ5 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 0 ; ; 78.903 0.013382 3590200 4179.8 3952.2 4006.5 4354.1 3962.5 3988.4 3388.6 3097.9 3965.7 3892.8 FALSE FALSE TRUE 3848.964419 4293.810557 4154.984414 4336.083888 3915.249775 3161.160881 3483.674996 4042.435449 3530.672632 4028.07451 0.955534564 1.065970986 1.031506345 1.07646566 0.971990405 0.784782127 0.864848698 1.003565212 0.876516217 1 11.97587465 -5.50027522 24.38622002 0.99734769 0.881767418 0.338892941 0.072813689 430.3377924 464276.9481 0.009202131 0.02041905 3.16E-06 5.50027522 -0.115580273 ITMIAEPLEK ddPTM_HeLa_Curcumin_4h_R1 1 ITMIAEPLEK 10 0 Q15029-3;Q15029;Q15029-2;K7EP67 Q15029-3 EFTUD2 116 kDa U5 small nuclear ribonucleoprotein component 0 0 107.79 0.00016359 0 558.16 401.41 519.58 573.67 442.4 651.87 606.49 348.77 534.4 524.55 FALSE FALSE TRUE 513.981047 436.1060918 538.8360919 571.2963055 437.1246689 516.6648139 623.5064771 455.1083675 475.777657 542.7780735 0.946945118 0.803470356 0.992737397 1.052541238 0.805346955 0.95188962 1.148731881 0.838479647 0.876560201 1 9.084218631 -8.96226663 1.130055349 0.996031788 0.947185731 0 0.109809941 1.391132211 3.493990395 0.043034315 0.018393719 1.09E-09 8.96226663 -0.048846057 ITNYGIEK ddPTM_HeLa_Curcumin_4h_R1 1 ITNYGIEK 8 0 O60938 O60938 KERA Keratocan 0 0 97.602 0.01561 1015200000 2157.2 1346 1620.6 1977.4 1780.8 2245.5 1852.7 1979.5 2267.5 1919.7 FALSE FALSE TRUE 1986.455344 1462.342242 1680.660862 1969.218043 1759.565123 1779.757988 1904.681776 2583.040438 2018.760923 1986.409432 1.000023113 0.73617363 0.846079783 0.991345496 0.885801837 0.895967347 0.958856591 1.30035651 1.016286416 1 10.9559473 -4.261710202 7.781299348 0.954865513 1.303529756 0.606300065 0.087794986 0.058270388 38.85211743 0.013452885 0.106701895 5.47E-05 4.261710202 0.348664242 ITPGNYGNT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 ITPGNYGNTPR 11 0 Q5VYS8-4;Q5VYS8;Q5VYS8-5;Q5VYS8-3;Q5VYS8-2;Q5VYS8-6 Q5VYS8-4 ZCCHC6 Terminal uridylyltransferase 7 1 0 ITPGNYGNT(1)PR 111.72 0.017628 10779000 3213 2776.5 2795.2 2704.3 2901.2 3852.4 3183.1 1336.9 3459.8 3049.3 TRUE FALSE FALSE 2958.68766 3016.488288 2898.792571 2693.110323 2866.605085 3053.368815 3272.409219 1744.514656 3080.268596 3155.262948 0.937699237 0.956018036 0.918716639 0.8535296 0.908515433 0.967706611 1.037127261 0.55289042 0.97623198 1 11.62354452 -4.25442707 24.9671029 0.956798556 0.55289023 0.857367606 0.0486077 237.8707593 846909.5201 0.007459508 0.099852277 5.57E-05 4.25442707 -0.403908327 SST(ph)PLPTISSSAENTR ddPTM_HeLa_Curcumin_4h_R1 4 SSTPLPTISSSAENTR 16 0 G5E972;P42167;H0YJH7;P42167-3;P42167-2;P42166 G5E972;P42166 TMPO "Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin" 1 0 S(0.046)S(0.007)T(0.947)PLPTISSSAENTR;S(0.005)S(0.009)T(0.986)PLPTISSSAENTR;SS(0.093)T(0.906)PLPTISSSAENTR;SST(1)PLPTISSSAENTR ;;; 235.93 4.29E-22 3607830000 15885.2 13689 14583.4 15330.5 13680.3 13539.8 9258.1 2222.84 17145 14492.4 TRUE FALSE FALSE 14627.86966 14872.21616 15123.87363 15267.06645 13517.17136 10731.49286 9517.857369 2900.573683 15264.23639 14996.00982 0.975450792 0.991744893 1.008526522 1.01807525 0.901384536 0.715623221 0.63469266 0.193423032 1.01788653 1 13.87229106 -4.441665302 0.99667261 0.992285228 1.02E-18 0.965740336 0.046746937 0.170124504 0.157559326 0.006697314 0.16761645 3.62E-05 4.441665302 -0.992285228 down ITPLEIEVLEETVQTMDTS ddPTM_HeLa_Curcumin_4h_R1 2 ITPLEIEVLEETVQTMDTS 19 0 Q99436 Q99436 PSMB7 Proteasome subunit beta type-7 0 0 ; ; 130.15 0.00079527 51472000 3352.6 2692.22 2539.9 2245.98 2776.3 4978.7 3617.5 3403.1 3497.3 2974.5 FALSE FALSE TRUE 3087.238172 2924.923501 2634.030928 2236.68673 2743.194436 3946.061498 3718.997314 4440.689524 3113.65494 3077.863654 1.003045788 0.95030964 0.855798445 0.726701044 0.891265743 1.282078072 1.208304763 1.442783055 1.011628613 1 11.58771361 -5.251549193 22.64829571 0.958843422 1.300780408 0.747900587 0.102297698 90.213808 206584.6363 0.016136739 0.040485453 5.60E-06 5.251549193 0.341936986 ITPLSLQTQGSS(ph)HETLNIVEEK ddPTM_HeLa_Curcumin_4h_R1 3 ITPLSLQTQGSSHETLNIVEEK 22 0 O43491;Q6R5J7;E9PMV8 O43491 EPB41L2 Band 4.1-like protein 2 1 0 IT(0.004)PLS(0.039)LQT(0.047)QGS(0.233)S(0.628)HET(0.05)LNIVEEK;ITPLSLQT(0.005)QGS(0.366)S(0.628)HETLNIVEEK;ITPLSLQTQGS(0.039)S(0.941)HET(0.02)LNIVEEK ;; 107.87 1.66E-05 59010900 4666.2 3698.91 3038.73 3133.07 5723.5 8141.2 4156.3 2853.05 5858 3607.7 TRUE FALSE FALSE 4296.865346 4018.627298 3151.348007 3120.106186 5655.251001 6452.62335 4272.914592 3722.931811 5215.392056 3733.067306 1.151028094 1.076494734 0.844171227 0.835802285 1.514907323 1.728504423 1.144612256 0.997284942 1.397079567 1 11.86614581 -5.756149137 24.99986432 1.039762007 1.359217388 0.270910954 0.236749782 120.1968672 568002.5348 0.032174192 0.062857685 1.75E-06 5.756149137 0.31945538 ITPPAAKPGS(ph)PQAK ddPTM_HeLa_Curcumin_4h_R1 1 ITPPAAKPGSPQAK 14 1 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3;A0A0A0MSW3;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 0 ITPPAAKPGS(1)PQAK 159.18 0.0030327 358490000 3807.8 3140.5 3205.5 3469.9 3034.3 3619.7 2848.6 2329.4 3389.4 3032.1 TRUE FALSE FALSE 3506.408612 3411.950826 3324.29865 3455.542473 2998.117954 2868.933418 2928.524049 3039.623337 3017.5913 3137.465249 1.117592812 1.087486412 1.059549154 1.101380318 0.955586028 0.914411217 0.933404458 0.968814981 0.96179274 1 11.61538376 -5.679035148 6.171781469 1.062594295 0.93836251 0.586102538 0.045705362 0.109490965 6.514008399 0.006975279 0.014018951 2.09E-06 5.679035148 -0.124231785 ITPSYVAFTPEGER ddPTM_HeLa_Curcumin_4h_R1 2 ITPSYVAFTPEGER 14 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 0 ; ; 180.66 7.15E-08 11640100 595.87 352.17 456.04 480.72 491.41 574.13 474.1 157.47 509.26 583.27 FALSE FALSE TRUE 548.7062607 382.6100056 472.9412436 478.730908 485.5502567 455.0489662 487.40197 205.4818781 453.3954521 603.5385891 0.909148596 0.63394456 0.783613926 0.793206792 0.804505736 0.753968304 0.80757383 0.340461872 0.751228605 1 9.237302207 -3.384711245 0.155210546 1.074404702 4.79E-13 0.252984251 0.144033903 17.46710718 0.348051977 0.297662338 3.86373427 0.000412372 3.384711245 -1.074404702 ITQYWPDRETAPGDISPYTIPEEDR ddPTM_HeLa_Curcumin_4h_R1 1 ITQYWPDRETAPGDISPYTIPEEDR 25 1 E9PLB2 E9PLB2 IPO7 0 0 52.451 0.0064647 3399300 801.62 633.81 557.17 541.48 563.53 686.41 635.05 477.21 562.43 594.86 FALSE FALSE TRUE 738.1709311 688.5937122 577.8192103 539.2394992 556.8102728 544.0408286 652.8677939 622.7091322 500.7328361 615.5313407 1.199241829 1.118698053 0.938732396 0.87605531 0.90460101 0.88385561 1.060657274 1.011661131 0.813496898 1 9.265688505 -6.757936348 24.99731703 1.098561182 0.943266227 0.0063494 0.113815223 70.22186212 501094.3461 0.014823919 0.020489804 1.75E-07 6.757936348 -0.155294955 ITS(ph)EAEDLVANFFPK ddPTM_HeLa_Curcumin_4h_R1 1 ITSEAEDLVANFFPK 15 0 B7Z8D3;A0A087WTV2;K7ENH2;K9J957;P61289;P61289-3;P61289-2 B7Z8D3 PSME3 Proteasome activator complex subunit 3 1 0 IT(0.117)S(0.883)EAEDLVANFFPK 132.06 0.00068416 71593000 701.62 530.49 436.3 449.16 554.11 744.52 434.98 455.64 550.1 578.33 TRUE FALSE FALSE 646.0860367 576.3431918 452.4696618 447.3014949 547.5026002 590.0981595 447.1843681 594.5625385 489.7554063 598.4269245 1.079640655 0.963097027 0.756098436 0.747462182 0.91490302 0.986082236 0.747266458 0.993542426 0.818404698 1 9.225031276 -6.978777297 7.285103797 1.036862934 0.855922457 0.093450825 0.111277333 0.10734898 24.30728654 0.014160884 0.018475548 1.05E-07 6.978777297 -0.180940477 VQMT(ph)SPSSTGSPMFK ddPTM_HeLa_Curcumin_4h_R1 1 VQMTSPSSTGSPMFK 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 0 VQMT(0.405)S(0.405)PS(0.108)S(0.029)T(0.051)GS(0.002)PMFK 99.747 0.011736 23273000 1832.4 1599.9 1836.1 1411.2 1555.6 2038.1 2019.8 5722.4 2199.1 1557.2 TRUE FALSE FALSE 1687.363606 1738.188227 1904.147481 1405.360828 1537.050486 1615.375086 2076.470152 7467.133417 1957.864232 1611.312584 1.047198181 1.078740552 1.181736865 0.872183859 0.953912047 1.002521238 1.28868239 4.63419295 1.215074127 1 10.65402068 -4.259550366 4.196181815 1.024003128 4.928969847 0.991836518 0.097185994 0.010601302 0.416345801 0.010993854 0.124186748 5.50E-05 4.259550366 3.904966719 up ITS(ph)PVLMGEENNVVHNQK ddPTM_HeLa_Curcumin_4h_R1 1 ITSPVLMGEENNVVHNQK 18 0 E9PMR6;Q9NZN5-2;Q9NZN5 E9PMR6 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 0 IT(0.455)S(0.545)PVLMGEENNVVHNQK 61.962 0.0095354 0 1587.6 1454.1 1074.9 1685.6 1503 1569.7 1249.2 1316.7 1587.3 1248.7 TRUE FALSE FALSE 1461.939785 1579.785925 1114.73674 1678.625434 1485.077707 1244.126526 1284.24919 1718.155769 1413.177161 1292.092232 1.13145157 1.222657242 0.862737746 1.299152949 1.1493589 0.96287749 0.993929967 1.329747 1.093712296 1 10.33549334 -9.273254075 0.959846162 0.998739806 1.112219855 0.021128741 0.142379221 1.188487655 1.931546292 0.093972028 0.024463084 5.33E-10 9.273254075 0.113480049 ITSDEPLTKDDIPVFLR ddPTM_HeLa_Curcumin_4h_R1 1 ITSDEPLTKDDIPVFLR 17 1 Q9UBB4-2;Q9UBB4;B1AHE4;A0A1W2PQD2 Q9UBB4-2 ATXN10 Ataxin-10 0 0 68.751 0.018081 8757700 1256.6 1027 1443.6 1686.6 1272.1 1449.7 1445.6 1188 1423.3 1421.1 FALSE FALSE TRUE 1157.138784 1115.769304 1497.101086 1679.621296 1256.931038 1149.015879 1486.159645 1550.215731 1267.167551 1470.483119 0.786910621 0.758777363 1.018101511 1.142224126 0.854774204 0.78138665 1.0106608 1.054222052 0.861735531 1 10.52207451 ITSFPESEGYS(ph)YETSTK ddPTM_HeLa_Curcumin_4h_R1 1 ITSFPESEGYSYETSTK 17 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 ITSFPES(0.005)EGYS(0.989)YET(0.005)S(0.001)TK 195.23 4.54E-26 0 1249.4 1165.3 1235.6 1450.7 1158.6 2065.9 1635.7 1217.5 1457.7 1139.7 TRUE FALSE FALSE 1150.508672 1266.02334 1281.392423 1444.697388 1144.784452 1637.409053 1681.59334 1588.710145 1297.793957 1179.30449 0.975582372 1.073533892 1.086566221 1.225041878 0.970728477 1.388453166 1.42591956 1.347158566 1.100474023 1 10.20372055 -5.257840541 0.614398003 0.989756909 1.493144796 0.64587134 0.09850523 0.499436686 0.248286159 0.017338738 0.141974275 5.52E-06 5.257840541 0.503387887 ITSGPFEPDLYK ddPTM_HeLa_Curcumin_4h_R1 2 ITSGPFEPDLYK 12 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 0 ; ; 146.11 1.78E-16 0 465.19 357.71 749.01 596.19 686.84 649.29 435.92 402.81 331.52 504.19 FALSE FALSE TRUE 428.3697206 388.6288585 776.7689695 593.7231237 678.6498816 514.619935 448.150742 525.6249147 295.1530854 521.710565 0.821086919 0.744912763 1.488888709 1.138031628 1.300816827 0.986408882 0.85900262 1.007502914 0.565741055 1 9.027105839 LEPVSPPS(ph)PPHTDPELELVPPR ddPTM_HeLa_Curcumin_4h_R1 1 LEPVSPPSPPHTDPELELVPPR 22 0 Q9Y618;C9J0Q5;Q9Y618-4;C9JE98;Q9Y618-5;C9JQE8;H7C1Y3;H0YGK8;C9J330 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 LEPVS(0.004)PPS(0.982)PPHT(0.014)DPELELVPPR 65.149 0.0020011 20850000 2341.9 1787 1847.9 2159.5 1647.7 2008.2 1173.2 452.39 2225 2043.3 TRUE FALSE FALSE 2156.536144 1941.460317 1916.3848 2150.564561 1628.052254 1591.676683 1206.116834 590.3216285 1980.923067 2114.304523 1.019974238 0.918250089 0.906390153 1.017149866 0.770017865 0.752813356 0.57045559 0.279203692 0.936914737 1 11.04596747 -4.439477279 0.692737821 1.00226148 1.31E-15 0.932540044 0.058292316 0.353931928 0.136125095 0.009000457 0.26384075 3.64E-05 4.439477279 -1.00226148 down ITSPLMEPS(ph)SIEK ddPTM_HeLa_Curcumin_4h_R1 1 ITSPLMEPSSIEK 13 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 0 ITSPLMEPS(0.5)S(0.5)IEK 89.46 0.012971 9104200 1126.2 1091.1 1143.8 1104 1164.8 1178.2 1303.9 1020.9 1042.9 1097.6 TRUE FALSE FALSE 1037.060082 1185.409822 1186.190234 1099.431941 1150.910521 933.8280389 1340.483925 1332.16771 928.4964792 1135.741518 0.913112768 1.043732049 1.044419188 0.968030069 1.013356034 0.822218809 1.18027201 1.172949733 0.817524467 1 10.14941882 -4.73279555 24.99399231 0.967514924 1.176611253 0.560546004 0.078405861 100.1772024 87411.02851 0.008790708 0.03287993 1.85E-05 4.73279555 0.209096329 ITSPLMEPSSIEK ddPTM_HeLa_Curcumin_4h_R1 1 ITSPLMEPSSIEK 13 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 0 0 152.67 0.00015734 1237300 603.3 585.84 595.23 645.16 644.72 1097.7 795.28 734.37 956.08 758.82 FALSE FALSE TRUE 555.5481684 636.4773991 617.2897474 642.4904989 637.0321351 870.0246464 817.5934164 958.2760324 851.200416 785.1889385 0.707534379 0.810604134 0.786167147 0.81826229 0.811310633 1.108044961 1.041269657 1.220440056 1.084070819 1 9.616896039 -5.256251358 23.89024635 0.842878556 1.115053414 0.537473532 0.111192953 140.8978308 648812.0915 0.016616932 0.040948157 5.54E-06 5.256251358 0.272174858 ITTSLLPINNGSK ddPTM_HeLa_Curcumin_4h_R1 1 ITTSLLPINNGSK 13 0 Q13596-2;Q13596;Q13596-3;J3KPH4;H0YKD5;H0YKL5;H0YK58 Q13596-2 SNX1 Sorting nexin-1 0 0 101.89 0.0055158 0 339.47 335.71 260.26 359.17 312.95 343.41 190.43 260.36 365.93 394.7 FALSE FALSE TRUE 312.6005913 364.7272765 269.9054645 357.6838497 309.2182756 272.182895 195.7729533 339.7425654 325.7883945 408.4157956 0.765397898 0.893029311 0.660859515 0.875783585 0.757116348 0.666435769 0.479347164 0.831854618 0.797688038 1 8.673894854 -13.52287874 0.102387671 1.91829256 0.533853419 0.203205784 0.123379471 67.97543199 0.517559263 13.26451706 0.829193284 3.00E-14 13.52287874 -1.384439141 ITVNGDSS(ph)AEAEELANEI ddPTM_HeLa_Curcumin_4h_R1 2 ITVNGDSSAEAEELANEI 18 0 A0A0B4J1W3;Q9BXJ9 A0A0B4J1W3 NAA15 "N-alpha-acetyltransferase 15, NatA auxiliary subunit" 1 0 ITVNGDS(0.066)S(0.934)AEAEELANEI;ITVNGDS(0.005)S(0.995)AEAEELANEI ; 222.11 1.98E-17 73660000 8222.8 7672.9 7805.9 8348.4 8458.4 9312.2 8053.4 5874.3 7454.1 7203.3 TRUE FALSE FALSE 7571.956703 8336.111286 8095.193521 8313.856533 8357.539104 7380.74475 8279.356729 7665.347028 6636.403879 7453.614139 1.015877206 1.118398556 1.086076281 1.115412789 1.121273378 0.990223617 1.110784188 1.028406741 0.890360536 1 12.86372442 -7.374443472 6.155456536 1.006987172 1.082014314 0.42872714 0.054591436 0.158626733 7.609471984 0.006613094 0.007531696 4.22E-08 7.374443472 0.075027142 ITVNGDSSAEAEELANEI ddPTM_HeLa_Curcumin_4h_R1 1 ITVNGDSSAEAEELANEI 18 0 A0A0B4J1W3;Q9BXJ9 A0A0B4J1W3 NAA15 "N-alpha-acetyltransferase 15, NatA auxiliary subunit" 0 0 97.631 0.0039792 0 642.39 467.32 411.78 591.34 617.23 799.69 592.54 709.48 699.83 668.4 FALSE FALSE TRUE 591.5441537 507.7130585 427.040929 588.8931918 609.8699354 633.8252796 609.1650777 925.797186 623.0603999 691.6268502 0.855293795 0.734085234 0.617444116 0.851460859 0.881790427 0.916426653 0.880771297 1.338579012 0.900862076 1 9.433850068 -4.261180576 24.09491638 0.884040518 1.338579175 0.650013001 0.104996294 7.626191251 709326.6826 0.01752243 0.13662135 5.48E-05 4.261180576 0.454538657 ITVTSEVPFSK ddPTM_HeLa_Curcumin_4h_R1 2 ITVTSEVPFSK 11 0 K7ERI7;P35268;K7EP65;K7EKS7;K7ELC4;K7EMH1;K7EJT5 K7ERI7 RPL22 60S ribosomal protein L22 0 0 ; ; 192.12 3.61E-16 6786500 5144.6 3210.1 3770.1 3987.5 4076.7 5721.3 4865.8 3934.7 3734.3 3277 FALSE FALSE TRUE 4737.399481 3487.56674 3909.823223 3971.000782 4028.088015 4534.637888 5002.321252 5134.371917 3324.656633 3390.875506 1.397102156 1.028515124 1.153042397 1.171084215 1.187919759 1.33730592 1.475229994 1.514172935 0.980471453 1 11.7274421 -1.000000001 0.02871506 3.89E-10 3.103490081 0.519644937 0.129096627 1203.577058 2.679509214 94.77106235 219.2927957 0.1 1.000000001 3.103490081 ITVTSEVPFSKR ddPTM_HeLa_Curcumin_4h_R1 2 ITVTSEVPFSKR 12 1 K7ERI7;P35268;K7EP65;K7EKS7;K7ELC4;K7EMH1 K7ERI7 RPL22 60S ribosomal protein L22 0 0 ; ; 89.266 0.0068241 6243600 3076.2 2415.38 2445.97 2436.3 2031.43 3152.4 2637.6 2732.6 3484.9 2826.4 FALSE FALSE TRUE 2832.715524 2624.154684 2536.6198 2426.219236 2007.206524 2498.556705 2711.603957 3565.757161 3102.615189 2924.61719 0.968576515 0.89726433 0.867333957 0.829585234 0.686314274 0.85431923 0.927165431 1.219221843 1.060861982 1 11.51403208 -7.308171008 2.489862034 0.987349578 0.883561156 0.129219799 0.127726901 0.478673262 5.636649111 0.023049999 0.026838969 4.92E-08 7.308171008 -0.103788422 IVADK(ac)DYSVTANSK ddPTM_HeLa_Curcumin_4h_R1 2 IVADKDYSVTANSK 14 1 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;C9J7H8;F5H793 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain;L-lactate dehydrogenase 0 1 ; IVADK(1)DYSVTANSK;IVADK(1)DYSVTANSK 306.44 1.11E-132 15058100 3849.9 5009.9 3778.1 3592.2 7473.2 8860.8 7213.7 5866.1 9734.1 3687.3 FALSE TRUE FALSE 3545.176353 5442.933432 3918.11971 3577.336428 7384.086971 7022.970198 7416.097007 7654.646886 8666.293584 3815.433401 0.929167405 1.426557054 1.026913406 0.93759635 1.93532063 1.840674299 1.94371025 2.006232604 2.27137855 1 11.89763123 -5.759155294 24.99263384 1.007326726 1.925871445 0.270138432 0.424159608 12.99182328 142154.2654 0.021908617 0.042189328 1.74E-06 5.759155294 0.918544719 IVADKDYSVTANS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 IVADKDYSVTANSK 14 1 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;C9J7H8;F5H793 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain;L-lactate dehydrogenase 1 0 IVADKDYSVT(0.006)ANS(0.994)K 71.781 0.01329 23572000 1754.9 1338.5 1580.3 1450 1683.7 1993.7 1499.5 1215.7 1509.9 1562.3 TRUE FALSE FALSE 1615.997813 1454.193976 1638.867308 1444.000284 1663.622977 1580.184146 1541.571934 1586.361334 1344.267748 1616.589809 0.9996338 0.899544194 1.013780552 0.893238518 1.029094065 0.977479963 0.953594985 0.981301085 0.831545356 1 10.65873794 IVADKDYSVTANSK ddPTM_HeLa_Curcumin_4h_R1 2 IVADKDYSVTANSK 14 1 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;C9J7H8;F5H793 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain;L-lactate dehydrogenase 0 0 ; ; 198.85 2.61E-13 63608000 15131.7 12366.1 13229.1 14354.5 13976.5 16649.9 12007.4 11700.9 16004.1 14670.2 FALSE FALSE TRUE 13934.00998 13434.97058 13719.38208 14295.10488 13809.83937 13196.52306 12344.29533 15268.45055 14248.49027 15179.98836 0.917919675 0.885044854 0.903780804 0.941707236 0.909739786 0.869336836 0.813195309 1.005827553 0.938636443 1 13.88988306 -8.916941891 0.496011573 1.01366566 0.897360463 0.15235823 0.050537804 0.99116771 0.403858028 0.05473175 0.012869307 1.21E-09 8.916941891 -0.116305198 IVAEEFLK ddPTM_HeLa_Curcumin_4h_R1 1 IVAEEFLK 8 0 H7C0A3;F8WCF6;P59998;P59998-3;R4GN08;P59998-4 H7C0A3 ARPC4-TTLL3;ARPC4 Actin-related protein 2/3 complex subunit 4 0 0 133.12 0.0013608 1485000 1531 1032.1 1371.1 1121 1324.3 1401.6 1394.9 1130.9 1237.5 1421.6 FALSE FALSE TRUE 1409.819734 1121.310125 1421.914172 1116.361599 1308.508587 1110.892361 1434.03714 1475.706204 1101.749346 1471.000494 0.958408743 0.762277191 0.966630656 0.758913137 0.88953647 0.755195097 0.974871963 1.003198986 0.748979589 1 10.52258202 -7.481399299 13.73592299 0.981662878 0.871341078 0 0.114025866 2.568724204 850.3527212 0.014377572 0.01618776 3.30E-08 7.481399299 -0.110321799 IVAERPGTNSTGPAPMAPPR ddPTM_HeLa_Curcumin_4h_R1 2 IVAERPGTNSTGPAPMAPPR 20 1 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 0 0 ; ; 101.28 0.0010792 5856700 1066.84 829.76 1070.79 1184.26 931.47 1408.7 1231.25 804.5 897.79 1052.92 FALSE FALSE TRUE 982.3984883 901.4807571 1110.474419 1179.359846 920.3628286 1116.519741 1265.795561 1049.788347 799.3046832 1089.508892 0.90168928 0.827419367 1.019243099 1.082469225 0.844750177 1.024791766 1.161803792 0.963542707 0.733637595 1 10.08946226 -6.616694957 20.12440125 0.941886477 1.018430996 0.206394423 0.109243481 6.069745997 1293.18578 0.014396944 0.020360349 2.42E-07 6.616694957 0.076544519 IVAHAVEVPAVQS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 IVAHAVEVPAVQSPR 15 0 H0YCL8;B5MBX0;Q96FF9 H0YCL8 CDCA5 Sororin 1 0 IVAHAVEVPAVQS(1)PR;IVAHAVEVPAVQS(1)PR ; 134.08 0.00030544 85857000 6510.6 5915.5 6161.6 6069.9 6263.3 10407.2 9956.9 4742.5 7785.5 6867.5 TRUE FALSE FALSE 5995.27914 6426.809461 6389.954316 6044.784362 6188.614238 8248.629407 10236.26382 6188.466418 6931.450128 7106.145114 0.843675304 0.904401663 0.899215287 0.850641841 0.870882052 1.160774129 1.440480549 0.87086125 0.97541635 1 12.79485143 -5.228248631 7.168100815 0.911833499 1.187193229 0.409451259 0.136713065 0.151394442 26.38319249 0.018166091 0.04602076 5.91E-06 5.228248631 0.27535973 IVALMDTYS(ph)PSLPK ddPTM_HeLa_Curcumin_4h_R1 1 IVALMDTYSPSLPK 14 0 K7EQE0;K7EM53;K7EJY2;K7EJS9;K7ERF3;K7ELU8;D3DUE4;F6WF08;Q6ZW76-2;Q6ZW76 K7EQE0 ANKS3 Ankyrin repeat and SAM domain-containing protein 3 1 0 IVALMDT(0.079)YS(0.812)PS(0.109)LPK 145.71 0.00062218 10765000 2762.4 2104.1 2128.8 2356.7 1849.8 3415.3 1848.4 1223.6 2109.2 2033.3 TRUE FALSE FALSE 2543.753125 2285.969028 2207.695201 2346.9486 1827.742343 2706.928282 1900.261129 1596.670007 1877.826037 2103.957024 1.209032835 1.086509374 1.049306224 1.115492652 0.868716577 1.286589151 0.903184384 0.758889079 0.8925211 1 11.03888952 -4.547261438 9.64118695 1.091326485 0.794531962 0.368807938 0.123713499 0.157013358 59.66492576 0.015461451 0.058891792 2.84E-05 4.547261438 -0.296794523 IVDQIRPDR ddPTM_HeLa_Curcumin_4h_R1 2 IVDQIRPDR 9 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2;P17844-2;P17844;J3KTA4;J3KRZ1;J3QSF1 A0A1X7SBZ2;P17844-2 DDX17;DDX5 Probable ATP-dependent RNA helicase DDX17;Probable ATP-dependent RNA helicase DDX5 0 0 ; ; 132.76 0.0030056 9613100 5171.7 3883.2 4175.1 4751.9 4129 5424.2 4593.1 3700.3 5552.2 4390.9 FALSE FALSE TRUE 4762.354488 4218.846505 4329.832879 4732.237897 4079.764372 4299.159777 4721.970024 4828.504436 4943.137551 4543.483448 1.048172518 0.928548888 0.952976483 1.041543994 0.897937545 0.946225473 1.039284082 1.06273182 1.087962047 1 12.14958311 -7.286506365 24.96040709 1.022748132 0.980219699 0.186675348 0.055508811 1207.764592 1202625.984 0.009182988 0.010503603 5.17E-08 7.286506365 -0.042528433 IVDRIDNDGDGFVTTEELK ddPTM_HeLa_Curcumin_4h_R1 1 IVDRIDNDGDGFVTTEELK 19 1 Q15293;Q15293-2 Q15293 RCN1 Reticulocalbin-1 0 0 165.17 8.17E-06 6994900 3296.4 2510.6 2758.6 2681.6 2424 2998.6 2142.9 2294.9 3382.1 2903.5 FALSE FALSE TRUE 3035.486462 2727.605077 2860.836143 2670.50425 2395.095383 2376.656559 2203.024007 2994.604446 3011.092092 3004.396409 1.010348186 0.907871235 0.952216603 0.888865478 0.79719686 0.791059579 0.733266755 0.996740789 1.002228628 1 11.55285946 -6.467563913 1.072327776 1.004098358 0.82054438 0.5035747 0.068491919 0.242912582 0.556622616 0.011656769 0.02123938 3.41E-07 6.467563913 -0.183553978 IVDS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 2 IVDSPEK 7 0 E9PQC4;Q9BZD4 E9PQC4 NUF2 Kinetochore protein Nuf2 1 0 IVDS(1)PEK;IVDS(1)PEK ; 123.86 0.010033 97336000 12857.5 11926.8 12438.2 13369.9 16038.2 14747.6 13047.9 10718 11731.4 11349.5 TRUE FALSE FALSE 11839.81531 12957.69945 12899.17063 13314.5789 15846.95494 11688.78152 13413.98896 13985.86886 10444.49477 11743.89428 1.008167736 1.103356275 1.09837251 1.133744785 1.349378201 0.995307114 1.142209614 1.190905549 0.889355313 1 13.51962327 -6.97398781 1.397795321 1.001764105 1.158759191 0.455357716 0.089281639 0.274944226 1.056588153 0.01459225 0.019584909 1.06E-07 6.97398781 0.156995086 IVDVIGEK ddPTM_HeLa_Curcumin_4h_R1 1 IVDVIGEK 8 0 P13861-2;P13861;H7C4A9 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 0 0 105.57 0.0089638 1015700 1689.8 1085.2 1383.8 1251.9 1696.7 1769.7 1303.2 1136.6 1655.9 1204.3 FALSE FALSE TRUE 1556.050547 1178.999852 1435.084845 1246.71997 1676.467961 1402.644271 1339.764285 1483.144108 1474.251913 1246.149335 1.248687058 0.946114417 1.151615464 1.000457918 1.345318665 1.125582811 1.075123379 1.190181679 1.183045941 1 10.28326125 IVEDEPNKICEADR ddPTM_HeLa_Curcumin_4h_R1 1 IVEDEPNKICEADR 14 1 P55060-4;P55060-3;P55060;P55060-2 P55060-4 CSE1L Exportin-2 0 0 123.26 0.0013092 12437000 918.3 963.42 1173 1186.2 847.09 1289.3 858.48 858.28 1036 1121.9 FALSE FALSE TRUE 845.615586 1046.693732 1216.472412 1181.291819 836.989005 1021.884647 882.5666383 1119.965621 922.3533919 1160.885941 0.728422626 0.901633567 1.047882801 1.017577849 0.720991594 0.880262746 0.760252671 0.964750783 0.794525421 1 10.18101052 -5.754089748 24.99930001 0.895050132 0.829949247 0.102920998 0.111683009 464.4324179 1579722.713 0.019525062 0.038429602 1.76E-06 5.754089748 -0.065100885 IVEGQGQSSEVIT(ph)PPEEISR ddPTM_HeLa_Curcumin_4h_R1 2 IVEGQGQSSEVITPPEEISR 20 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 0 IVEGQGQS(0.002)S(0.002)EVIT(0.996)PPEEISR;IVEGQGQSS(0.001)EVIT(0.995)PPEEIS(0.004)R ; 133.92 0.00029014 10719000 889.01 846.05 878.87 901.95 963.6 1254.77 872.8 808.49 1175.72 1021.64 TRUE FALSE FALSE 818.6439204 919.1787921 911.4416953 898.2179699 952.1096993 994.5165578 897.288419 1054.994879 1046.746458 1057.141914 0.774393589 0.869494228 0.862175346 0.849666405 0.900645114 0.940759745 0.8487871 0.997969019 0.990166451 1 10.04595335 -4.24851459 23.45838727 0.886273488 0.997969189 0.181492989 0.065595312 1418.173847 2573863.942 0.011517212 0.263672065 5.64E-05 4.24851459 0.111695701 IVEMSTSK ddPTM_HeLa_Curcumin_4h_R1 1 IVEMSTSK 8 0 I3L397;I3L504;P63241;P63241-2;F8WCJ1;C9J7B5;C9J4W5;Q9GZV4 I3L397 EIF5A;EIF5A2 Eukaryotic translation initiation factor 5A;Eukaryotic translation initiation factor 5A-1;Eukaryotic translation initiation factor 5A-2 0 0 125.31 0.0021501 8706300 3266.4 3363.8 3992.7 3042.1 3506.7 4337.5 3227 3053.3 3257.2 4056.6 FALSE FALSE TRUE 3007.860993 3654.551883 4140.672974 3029.512596 3464.884893 3437.853606 3317.540935 3984.237114 2899.893309 4197.566548 0.716572557 0.870635841 0.986446058 0.721730689 0.825450854 0.819011102 0.790348622 0.949177832 0.690851062 1 12.03533748 -9.577967666 1.365552846 0.999857667 0.819277084 0 0.125955067 0.365480185 1.223510296 0.060297043 0.014134895 2.64E-10 9.577967666 -0.180580584 LVSEK(ac)LASYQAAR ddPTM_HeLa_Curcumin_4h_R1 2 LVSEKLASYQAAR 13 1 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1;A0A494C1T8 H0YBT0 MYC Myc proto-oncogene protein 0 1 ; LVSEK(1)LASYQAAR;LVSEK(1)LASYQAAR 263.29 2.84E-77 85155000 3640.2 2807.35 3209.8 2499.55 2679.23 5152.9 1859.11 360.5 3133.95 3162 FALSE TRUE FALSE 3352.074329 3050.004825 3328.758012 2489.207524 2647.281932 4084.130455 1911.271623 470.4147905 2790.163526 3271.879265 1.024510398 0.932187461 1.017384122 0.760788319 0.809101351 1.248252189 0.584151024 0.143775107 0.852770931 1 11.6759038 -4.497150988 3.720597168 0.986674769 0.188659017 0.774917108 0.136168928 0.067093805 1.891431323 0.017488489 0.104342993 3.18E-05 4.497150988 -0.798015752 down IVENEK(ac)INAEK ddPTM_HeLa_Curcumin_4h_R1 2 IVENEKINAEK 11 1 Q9C005 Q9C005 DPY30 Protein dpy-30 homolog 0 1 ; IVENEK(1)INAEK;IVENEK(1)INAEK 227.36 3.91E-40 7448100 3330.4 2893.1 2749.3 3012.1 2967.8 3433.6 2274.2 2666 3424.3 2999.1 FALSE TRUE FALSE 3066.795326 3143.166673 2851.191477 2999.636728 2932.410923 2721.432655 2338.007931 3478.851127 3048.662857 3103.318502 0.988230929 1.012840503 0.918755672 0.966590031 0.944927477 0.876942748 0.753389615 1.121010017 0.982388 1 11.59959606 -6.308842859 1.060704443 0.99585655 0.908918889 0.09342301 0.086770847 0.656441708 1.463106207 0.014152225 0.028493182 4.91E-07 6.308842859 -0.086937661 IVENEKINAEK(ac)SSK ddPTM_HeLa_Curcumin_4h_R1 1 IVENEKINAEKSSK 14 2 Q9C005 Q9C005 DPY30 Protein dpy-30 homolog 0 1 IVENEKINAEK(1)SSK 102.63 0.00096227 2629600 1889.4 1458 1497.5 1773.3 1153.1 1988.1 1140.8 1463.4 2832.9 1903.9 FALSE TRUE FALSE 1739.851996 1584.023023 1552.998667 1765.962554 1139.350036 1575.745649 1172.807778 1909.583923 2522.137958 1970.060383 0.883146532 0.804047955 0.788300034 0.896400217 0.578332545 0.799846372 0.59531565 0.96930223 1.280233834 1 10.94402413 -7.584836791 0.531799295 0.990831884 0.740868976 0.426181917 0.145962527 0.508448854 0.345100353 0.043400777 0.039076428 2.60E-08 7.584836791 -0.249962908 IVEPEVVGES(ph)DS(ph)EVEGDAWR ddPTM_HeLa_Curcumin_4h_R1 2 IVEPEVVGESDSEVEGDAWR 20 0 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 2 0 IVEPEVVGES(1)DS(1)EVEGDAWR;IVEPEVVGES(1)DS(1)EVEGDAWR ; 97.623 0.0014931 4401800 5050.7 4772.98 5346 4674.46 5001.46 5565.1 4450.71 4656.2 5370.5 4702.8 TRUE FALSE FALSE 4650.931766 5185.535123 5544.127463 4655.118323 4941.820856 4410.835528 4575.584944 6075.853945 4781.369586 4866.22195 0.955758248 1.065618292 1.139308383 0.956618578 1.015535441 0.906418896 0.94027461 1.248577235 0.982562989 1 12.24858641 -4.254657997 24.51818392 0.989307844 1.248577392 0.584346655 0.063749631 331.0403663 1196839.627 0.009061554 0.117402835 5.56E-05 4.254657997 0.259269548 IVEPEVVGES(ph)DSEVEGDAWR ddPTM_HeLa_Curcumin_4h_R1 3 IVEPEVVGESDSEVEGDAWR 20 0 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 1 0 IVEPEVVGES(0.987)DS(0.013)EVEGDAWR;IVEPEVVGES(0.837)DS(0.163)EVEGDAWR;IVEPEVVGES(0.991)DS(0.009)EVEGDAWR ;; 138.28 0.00012051 105210600 3215.45 2898.7 2446.08 2202.19 2578.74 2475.56 2059.45 1563.27 3104.84 2408.88 TRUE FALSE FALSE 2960.94374 3149.250712 2536.733877 2193.077921 2547.99021 1962.100951 2117.232624 2039.903827 2764.24682 2492.588401 1.187899189 1.263445947 1.017710696 0.879839576 1.022226618 0.787174068 0.849411248 0.818387755 1.108986473 1 11.28342896 -6.034239798 1.37144451 1.103280107 0.841949189 0.654648322 0.089581542 0.246296618 0.918011615 0.017572761 0.037764905 9.24E-07 6.034239798 -0.261330918 IVEPEVVGESDS(ph)EVEGDAWR ddPTM_HeLa_Curcumin_4h_R1 1 IVEPEVVGESDSEVEGDAWR 20 0 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 1 0 IVEPEVVGES(0.425)DS(0.575)EVEGDAWR 197.09 2.77E-38 0 1615.8 1155.9 936.72 1269 1138.9 1577.9 936.25 621.03 1364.6 1132.1 TRUE FALSE FALSE 1487.907725 1255.810845 971.4356672 1263.749214 1125.319361 1250.625753 962.5186552 810.3791881 1214.906794 1171.440391 1.270152316 1.072022832 0.829265983 1.07879942 0.960628787 1.067596579 0.821653976 0.691780132 1.037105092 1 10.19406783 -3.522084286 0.5070397 1.111057974 1.54E-17 0.47416753 0.113481545 5.225352441 0.528277387 0.027807586 4.083454012 0.000300549 3.522084286 -1.111057974 IVEYS(ph)PPSAPR ddPTM_HeLa_Curcumin_4h_R1 3 IVEYSPPSAPR 11 0 O95696-2;O95696 O95696-2 BRD1 Bromodomain-containing protein 1 1 0 IVEYS(0.929)PPS(0.071)APR;IVEYS(0.998)PPS(0.002)APR;IVEYS(0.992)PPS(0.008)APR ;; 117.86 0.0044779 67935000 7646 6468.2 6963.7 7452.4 6811.5 7862.4 6570.6 4833.3 7800.3 6703.6 TRUE FALSE FALSE 7040.811032 7027.282386 7221.780848 7421.563943 6730.277311 6231.649612 6754.953352 6306.95092 6944.626605 6936.549601 1.015030734 1.013080392 1.041120047 1.069921556 0.970262984 0.898378873 0.973820378 0.909234603 1.001164412 1 12.7600025 -5.525601648 24.98715673 1.014746087 0.932230311 0.709055798 0.027475696 36.54824181 335391.2599 0.00396161 0.007961245 2.98E-06 5.525601648 -0.082515776 IVFSGNLFQHQEDSKK ddPTM_HeLa_Curcumin_4h_R1 1 IVFSGNLFQHQEDSKK 16 1 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 0 0 53.3 0.010839 2202700 1958.9 1743.2 1437.8 1284.6 1687.3 2536.6 1292.7 1649.3 1842.8 1566.8 FALSE FALSE TRUE 1803.850998 1893.87444 1491.086133 1279.284666 1667.18005 2010.480567 1328.969683 2152.163978 1640.64945 1621.246183 1.112632379 1.168159691 0.919716048 0.789074897 1.028332444 1.240083454 0.819721086 1.327475124 1.011968119 1 10.66288746 -2.987116903 0.004388918 0.260765263 1.866239438 0.013029187 0.164093858 424058.1103 209.9555823 36729.67993 40140.22465 0.001030109 2.987116903 1.605474175 IVGELEQMVSEDVPLDHR ddPTM_HeLa_Curcumin_4h_R1 1 IVGELEQMVSEDVPLDHR 18 0 Q00341;Q00341-2;A0A024R4E5 Q00341 HDLBP Vigilin 0 0 89.344 0.011869 3522400 1619.3 1628.5 1285.5 1506.8 1603.5 1909.4 1369.3 1505 1776.1 1543.7 FALSE FALSE TRUE 1491.130696 1769.260284 1333.141761 1500.565261 1584.37931 1513.368917 1407.718873 1963.867572 1581.266274 1597.34346 0.933506621 1.107626711 0.834599317 0.939413031 0.991883931 0.947428624 0.88128753 1.229458548 0.989935047 1 10.64145884 -4.250495265 24.79681572 0.962179804 1.229458721 0.575808891 0.069725377 762.6547463 1727961.947 0.009010166 0.176960677 5.62E-05 4.250495265 0.267278917 IVITGDGDIDHDQALAQAIR ddPTM_HeLa_Curcumin_4h_R1 2 IVITGDGDIDHDQALAQAIR 20 0 O43491;O43491-4;E9PHY5;E9PK52;O43491-3;O43491-2;E9PII3;Q6R5J7;E9PPC9;Q6ZSX4 O43491 EPB41L2 Band 4.1-like protein 2 0 0 ; ; 218.36 7.18E-19 8471900 2650.7 2118.3 1980.37 2264.22 2266.47 2608.8 2238.72 1929.11 2801.7 2358.5 FALSE FALSE TRUE 2440.894298 2301.396413 2053.764254 2254.851258 2239.443826 2067.705473 2301.532458 2517.286758 2494.36052 2440.457699 1.0001789 0.943018358 0.841548802 0.923946052 0.917632715 0.847261345 0.943074104 1.031481414 1.022087177 1 11.25293603 -7.151699541 4.042345147 1.000102849 0.914343152 0.385988149 0.050116097 0.178063541 5.091393768 0.008239059 0.010151087 7.05E-08 7.151699541 -0.085759698 IVLDNSVFSEHR ddPTM_HeLa_Curcumin_4h_R1 2 IVLDNSVFSEHR 12 0 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 0 ; ; 100.38 0.0072552 18276900 6617.9 6149.4 5843.3 5333.7 7933 10302.9 6582.8 5092.8 7933.2 6829.7 FALSE FALSE TRUE 6094.086232 6680.926735 6059.857838 5311.630563 7838.404156 8165.962402 6767.495651 6645.571276 7062.947808 7067.031567 0.862326165 0.945365345 0.857482775 0.751607024 1.109150862 1.155501051 0.957615031 0.940362472 0.999422139 1 12.78688864 -5.725189791 24.99999451 0.916418242 1.042928863 0.348797407 0.091176691 180.2345266 124300.2026 0.01428467 0.02856864 1.88E-06 5.725189791 0.126510622 IVNHWAS(ph)PELR ddPTM_HeLa_Curcumin_4h_R1 3 IVNHWASPELR 11 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 IVNHWAS(1)PELR;IVNHWAS(1)PELR;IVNHWAS(1)PELR ;; 127.3 0.0015351 49075600 17656 13307 14733.5 15424.1 15233.8 22016.8 16534.3 5505.5 16525 13980.8 TRUE FALSE FALSE 16258.50897 14457.19779 15279.53647 15360.27916 15052.14688 17450.2675 16998.20796 7184.101606 14712.24884 14466.63176 1.123862779 0.99934788 1.056191706 1.061773011 1.040473493 1.2062426 1.174994169 0.496598083 1.01697818 1 13.82044144 -4.255004864 24.94852301 1.070177123 0.49659782 0.86683128 0.068046209 204.33606 792249.3827 0.010284876 0.131128595 5.56E-05 4.255004864 -0.573579302 IVPQS(ph)QVPNPESPGKSFQPITMSCK ddPTM_HeLa_Curcumin_4h_R1 1 IVPQSQVPNPESPGKSFQPITMSCK 25 1 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 0 IVPQS(0.812)QVPNPES(0.153)PGKS(0.016)FQPIT(0.008)MS(0.011)CK 52.359 0.0087794 0 1080 913.86 908.79 1046.2 723.15 1050.8 656.44 582.35 1119.2 1112.3 TRUE FALSE FALSE 994.5168604 992.8499863 942.4705569 1041.871102 714.5269086 832.852235 674.8579397 759.9058342 996.4265601 1150.952342 0.864081703 0.862633447 0.818861496 0.905225233 0.620813636 0.723620088 0.586347423 0.660240921 0.865740938 1 10.16861238 -3.211958461 0.16173542 1.05041334 4.87E-16 0.674266067 0.07354388 9.025627784 0.177987919 0.127792652 2.03596363 0.000613821 3.211958461 -1.05041334 IVPQSQVPNPES(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 2 IVPQSQVPNPESPGK 15 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 0 IVPQSQVPNPES(1)PGK;IVPQSQVPNPES(1)PGK ; 237.06 3.40E-22 37698000 10306 9715.6 9968.5 9857.4 11445.2 11036.8 9199.9 3855.8 8782.3 8901.7 TRUE FALSE FALSE 9490.269225 10555.37317 10337.94138 9816.612691 11308.72347 8747.64327 9458.024434 5031.41567 7818.903662 9211.033412 1.030315362 1.145948853 1.122343272 1.065744988 1.227736667 0.94969184 1.026814692 0.546237913 0.848862805 1 13.16914731 -4.2541006 4.502869907 1.045631981 0.510031749 0.692959228 0.099930176 0.075855692 3.830313586 0.011459475 0.128944379 5.57E-05 4.2541006 -0.535600233 IVQK(ac)HPHTGDTK ddPTM_HeLa_Curcumin_4h_R1 2 IVQKHPHTGDTK 12 1 P51397;B4DQ75 P51397 DAP Death-associated protein 1 0 1 ; IVQK(1)HPHTGDTK;IVQK(1)HPHTGDTK 83.137 0.005283 12987200 6343.5 5853.7 6526.2 5627.9 6919.7 8564.2 6993 5224.5 6021.9 5295.1 FALSE TRUE FALSE 5841.405281 6359.667744 6768.066713 5604.613241 6837.187097 6787.888382 7189.204759 6817.425999 5361.312636 5479.104331 1.06612412 1.160713022 1.235250564 1.02290683 1.247865834 1.238868248 1.312113135 1.244259205 0.978501651 1 12.41972436 -6.000638334 0.27298991 0.979987123 1.374699499 0.697287984 0.063954629 1.331560205 0.178624221 0.05113414 0.178409618 9.99E-07 6.000638334 0.394712376 IVQK(ac)HPHTGDTKEEK ddPTM_HeLa_Curcumin_4h_R1 1 IVQKHPHTGDTKEEK 15 2 P51397;B4DQ75 P51397 DAP Death-associated protein 1 0 1 IVQK(1)HPHTGDTKEEK 58.32 0.010865 4535300 3965 3457.7 3365.4 3215.9 3849.1 5205.6 3577.9 2979.8 3761.5 3083 FALSE TRUE FALSE 3651.166066 3756.568181 3490.124685 3202.593458 3803.201996 4125.899881 3678.286245 3888.327303 3348.872861 3190.134021 1.144518081 1.177558108 1.09403701 1.003905616 1.192176245 1.293331206 1.153019347 1.218860173 1.049759301 1 11.63940132 -13.52287875 0.096151996 0.460028121 1.29166919 0.438816247 0.067794275 88.09449584 0.635879588 9.696090923 0.709109619 3.00E-14 13.52287875 0.831641069 IVRGDQPAASGDS(ph)DDDEPPPLPR ddPTM_HeLa_Curcumin_4h_R1 2 IVRGDQPAASGDSDDDEPPPLPR 23 1 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 0 IVRGDQPAAS(0.15)GDS(0.85)DDDEPPPLPR;IVRGDQPAASGDS(1)DDDEPPPLPR ; 171.16 1.90E-09 94617000 2264.7 2302.4 1859.67 2308.9 1775.97 2859.7 1981.82 1384.84 3075.8 2084.82 TRUE FALSE FALSE 2085.446605 2501.409197 1928.591006 2299.346384 1754.792718 2266.565985 2037.424535 1807.071341 2738.392435 2157.26734 0.966707541 1.159526754 0.893997221 1.065860657 0.813433127 1.050665322 0.944446939 0.837666852 1.269380194 1 11.07498926 -5.783547635 24.99990364 0.996091936 0.923839097 0.153255489 0.123972531 340.5112898 385047.8387 0.012140166 0.022018907 1.65E-06 5.783547635 -0.072252839 IVS(ph)GSPISTPSPS(ph)PLPR ddPTM_HeLa_Curcumin_4h_R1 1 IVSGSPISTPSPSPLPR 17 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 2 0 IVS(0.966)GS(0.027)PIS(0.008)T(0.008)PS(0.173)PS(0.819)PLPR 222.11 1.41E-15 5254100 1808.9 1583.3 1323.7 2168.6 1929.4 1701.7 1361.5 713.74 2036.5 1902.4 TRUE FALSE FALSE 1665.723656 1720.153397 1372.757486 2159.626908 1906.393165 1348.748238 1399.700026 931.3560403 1813.101045 1968.508258 0.84618576 0.873836007 0.697359272 1.097088061 0.968445602 0.685162601 0.711046052 0.47312783 0.921053309 1 10.94288705 -4.700652982 1.359862633 0.918154777 0.473614671 0.604004383 0.110776027 0.350316882 0.940129992 0.01731145 0.171256813 1.99E-05 4.700652982 -0.444540106 IVSAQS(ph)LAEDDVE ddPTM_HeLa_Curcumin_4h_R1 1 IVSAQSLAEDDVE 13 0 Q15388 Q15388 TOMM20 Mitochondrial import receptor subunit TOM20 homolog 1 0 IVS(0.004)AQS(0.996)LAEDDVE 104.98 0.0051246 2595000 1887.5 1521.4 1532.6 2005.2 2161.8 3361.7 2919.2 2018 1727.2 2093.6 TRUE FALSE FALSE 1738.102383 1652.903037 1589.399504 1996.903014 2136.021947 2664.445526 3001.104895 2633.27891 1537.730481 2166.352444 0.802317457 0.762988978 0.733675404 0.921781227 0.985999278 1.229922459 1.385326244 1.215535781 0.709824703 1 11.08105226 -5.317699981 2.275124013 0.879459888 1.30597605 0.797622525 0.100402465 0.117787315 1.178440831 0.016030573 0.045299207 4.81E-06 5.317699981 0.426516161 IVSAQSLAEDDVE ddPTM_HeLa_Curcumin_4h_R1 1 IVSAQSLAEDDVE 13 0 Q15388 Q15388 TOMM20 Mitochondrial import receptor subunit TOM20 homolog 0 0 137.46 0.0098245 15614000 4518.8 3477 3727.2 4079 4560.8 7061.6 4842 2980.8 5854 3743.2 FALSE FALSE TRUE 4161.132212 3777.536387 3865.333311 4062.122179 4506.415439 5596.944559 4977.853488 3889.632198 5211.830846 3873.275921 1.07431856 0.975282026 0.997949382 1.048756211 1.163463572 1.445015711 1.285179158 1.004222853 1.345587289 1 11.91933856 -5.644698293 3.73031935 1.028452932 1.255840367 0.179893413 0.144484885 0.142070101 3.755514524 0.014968201 0.031175271 2.27E-06 5.644698293 0.227387435 IVTDRETGSSK ddPTM_HeLa_Curcumin_4h_R1 1 IVTDRETGSSK 11 1 P19338;H7BY16 P19338 NCL Nucleolin 0 0 83.081 0.017897 9193500 3328.9 2591.8 2414.7 2492.4 2008.8 3485 2458.1 2813.6 3071.3 3216.8 FALSE FALSE TRUE 3065.414052 2815.823643 2504.190906 2482.087109 1984.846372 2762.171716 2527.06767 3671.453688 2734.386074 3328.583561 0.920936487 0.845952518 0.75232929 0.745688688 0.596303604 0.829833972 0.759202112 1.103007817 0.821486384 1 11.70069267 -7.351337342 1.511892189 0.97199882 0.786212886 0.094489997 0.129162636 0.32614676 1.431259617 0.023232928 0.026594893 4.45E-08 7.351337342 -0.185785934 IVTEETMT(ph)TT(ph)T(ph)VTEK ddPTM_HeLa_Curcumin_4h_R1 1 IVTEETMTTTTVTEK 15 0 Q12955-7;Q12955-5;Q12955-4;Q12955 Q12955-7 ANK3 Ankyrin-3 3 0 IVTEETMT(0.562)T(0.562)T(0.894)T(0.98)VT(0.002)EK 73.887 0.0056973 0 524.88 231.23 530.39 388.23 516.65 368.97 333.2 266.02 407.31 336.21 TRUE FALSE FALSE 483.3351941 251.2164909 550.04672 386.6236071 510.4892862 292.4414629 342.5486952 347.1282734 362.629112 347.8932725 1.389320324 0.72210793 1.581078921 1.111328208 1.467373262 0.840606835 0.984637308 0.997801052 1.042357357 1 8.44250097 -5.232533555 24.95567645 1.193614373 0.945377283 0.183222239 0.238347354 932.4215941 804999.4807 0.033252206 0.084760447 5.85E-06 5.232533555 -0.24823709 IVVAGNNEDVSFSRPADLDLIQSTPFKPLALKT(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 1 IVVAGNNEDVSFSRPADLDLIQSTPFKPLALKTPPR 36 3 Q9GZY8-5;C9JHF5;A0A0A0MS29;Q9GZY8-4;Q9GZY8-3;Q9GZY8-2;Q9GZY8 Q9GZY8-5 MFF Mitochondrial fission factor 1 0 IVVAGNNEDVSFSRPADLDLIQS(0.122)T(0.122)PFKPLALKT(0.755)PPR 40.463 0.0082185 14734000 999.01 608.73 835.4 767.13 839.5 4677 2374.8 2277.3 1192.8 752.47 TRUE FALSE FALSE 919.9373043 661.3459088 866.3606589 763.9558193 829.4895108 3706.937479 2441.430497 2971.638287 1061.952824 778.6182765 1.181499757 0.849384003 1.112689857 0.981168619 1.065335269 4.76091763 3.135593615 3.816553472 1.363894037 1 9.604772399 -5.273732183 24.91447605 1.06223015 3.827478746 0.917085972 0.389058161 114.4733768 232009.2193 0.048113197 0.10831808 5.32E-06 5.273732183 2.765248596 IVVELPHS(ph)VNSK ddPTM_HeLa_Curcumin_4h_R1 1 IVVELPHSVNSK 12 0 Q8N4Q0-2;Q8N4Q0 Q8N4Q0-2 ZADH2 Zinc-binding alcohol dehydrogenase domain-containing protein 2 1 0 IVVELPHS(0.5)VNS(0.5)K 111.95 0.0050007 122060000 1606.5 1193.5 1359.5 1613.1 1491.5 2238.8 1946.8 1318.4 1248.4 1509.8 TRUE FALSE FALSE 1479.34383 1296.660822 1409.884266 1606.42542 1473.714837 1774.447644 2001.421968 1720.374091 1111.453643 1562.265438 0.946922203 0.829987524 0.902461408 1.028266632 0.943319106 1.135817001 1.281102379 1.101204731 0.711437133 1 10.60942388 -5.163726512 3.925234754 0.959820734 1.194512235 0.550726563 0.102706971 0.098587332 2.735743329 0.009666948 0.026311494 6.86E-06 5.163726512 0.2346915 IVVELPHSVNS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 IVVELPHSVNSK 12 0 Q8N4Q0-2;Q8N4Q0 Q8N4Q0-2 ZADH2 Zinc-binding alcohol dehydrogenase domain-containing protein 2 1 0 IVVELPHS(0.309)VNS(0.691)K 92.439 0.013529 122350000 1342.7 1119.9 1365.4 1242.3 1449.5 1683.9 1518.3 1420.5 1361.6 1097.9 TRUE FALSE FALSE 1236.423878 1216.699166 1416.002925 1237.159692 1432.215659 1334.640159 1560.899412 1853.603911 1212.235887 1136.051943 1.088351537 1.070989027 1.246424456 1.08899923 1.260695576 1.174805577 1.373968348 1.631618978 1.067060264 1 10.14981308 -1 0.355370685 1.034546076 7.923312792 0.861287821 0.06684627 12.82388602 0.159878834 0.018551997 60.27463407 0.1 1 6.888766715 IVVLFYK ddPTM_HeLa_Curcumin_4h_R1 1 IVVLFYK 7 0 Q7L1Q6-2;Q7L1Q6;Q7L1Q6-4;Q7L1Q6-3;E7ETZ4;E9PFD4;B5MCE7;B5MCH7;Q9Y6E2 Q7L1Q6-2;E9PFD4 BZW1;BZW2 Basic leucine zipper and W2 domain-containing protein 1;Basic leucine zipper and W2 domain-containing protein 2 0 0 112.27 0.012408 670910 901.51 974.69 661.11 682.34 641.17 920.19 589.28 531.43 709.14 812.76 FALSE FALSE TRUE 830.1545322 1058.93786 685.6113182 679.5166579 633.5244665 729.3322213 605.8136108 693.4605606 631.3491162 841.0033495 0.98710015 1.259136317 0.815230187 0.807983296 0.753296009 0.867216785 0.720346252 0.824563375 0.750709396 1 9.715967736 -6.56197508 24.9992722 1.014751946 0.794214262 0.401196095 0.119998017 74.64614292 47730.53979 0.013016709 0.018408423 2.74E-07 6.56197508 -0.220537684 IVVNLTGR ddPTM_HeLa_Curcumin_4h_R1 2 IVVNLTGR 8 0 I3L3P7;I3L246;H3BN98;P62244 I3L3P7 RPS15A 40S ribosomal protein S15a 0 0 ; ; 129.68 0.0016933 5278000 3209.8 1949.76 2985.8 2151.89 2655.8 3271.7 2407.6 1944.06 2227.54 3073.4 FALSE FALSE TRUE 2955.740943 2118.288566 3096.456375 2142.986049 2624.13132 2593.11254 2475.150776 2536.794945 1983.184435 3180.200421 0.929419707 0.6660865 0.973667054 0.673852514 0.825146523 0.815392804 0.778300248 0.797683985 0.623603601 1 11.63490197 -7.453871523 6.6449047 0.969321305 0.794163432 0 0.136127852 0.135288908 10.58764683 0.012820154 0.014512527 3.52E-08 7.453871523 -0.175157873 IVVPPLPGK ddPTM_HeLa_Curcumin_4h_R1 2 IVVPPLPGK 9 0 A0A087X0R6;Q9UMY4-3;Q9UMY4;Q9UMY4-1 A0A087X0R6 SNX12 Sorting nexin-12 0 0 ; ; 114.19 0.0022555 2727900 7647.9 6646.6 7031.2 6920.8 6895.8 7511.8 6185.9 5801.9 7848.9 6939.4 FALSE FALSE TRUE 7042.560645 7221.102487 7291.782457 6892.163563 6813.572089 5953.768005 6359.459706 7570.872601 6987.895307 7180.543633 0.980783769 1.005648438 1.015491699 0.959838686 0.948893627 0.82915282 0.885651565 1.05435925 0.973170788 1 12.80987736 -5.821205021 2.66639625 0.993390668 0.917125319 0.236174157 0.054413725 0.257109944 3.723952832 0.00781996 0.015803613 1.51E-06 5.821205021 -0.076265349 IWHHTFYNELR ddPTM_HeLa_Curcumin_4h_R1 2 IWHHTFYNELR 11 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;C9JUM1;Q6S8J3;C9JZR7;A5A3E0;P0CG38;Q9BYX7;P0CG39;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65;P68133;P68032;A6NL76 P60709;P63261;P68133 ACTB;POTEE;POTEF;POTEI;POTEKP;POTEJ;ACTG1;ACTA1;ACTC1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;POTE ankyrin domain family member J;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1" 0 0 ; ; 95.483 0.0040343 49458000 1944.88 1099.43 1494.23 1109.52 1697.24 34457 7485.3 4721.6 2093.2 1551.98 FALSE FALSE TRUE 1790.940696 1194.45983 1549.607478 1104.9291 1677.001522 27310.22979 7695.317372 6161.194104 1863.581197 1605.911189 1.11521777 0.743789469 0.96493971 0.688038733 1.04426791 17.00606482 4.791869826 3.836572125 1.16045097 1 10.6491764 -5.437746579 24.99999249 0.993957458 8.312182012 0.527204785 3.289479703 46.92203565 13778.36887 0.433435322 0.969190754 3.65E-06 5.437746579 7.318224554 IWLS(ph)TETLANED ddPTM_HeLa_Curcumin_4h_R1 1 IWLSTETLANED 12 0 Q9NXD2 Q9NXD2 MTMR10 Myotubularin-related protein 10 1 0 IWLS(0.867)T(0.133)ETLANED 142.89 0.0010211 7428500 1158.4 1210.1 1445.2 1436.7 1170 1502.8 1178.1 983.29 1655.1 1114.7 TRUE FALSE FALSE 1066.711418 1314.695652 1498.760383 1430.755316 1156.048514 1191.10234 1211.154315 1283.090594 1473.539671 1153.435742 0.924812175 1.139808317 1.299387845 1.240429149 1.002265208 1.032656 1.050040562 1.112407521 1.277522117 1 10.17172192 -7.255920531 24.77651286 0.964494638 1.125221642 0 0.13196364 322.723687 1448848.733 0.016421944 0.019800792 5.55E-08 7.255920531 0.160727005 IWSTVPT(ph)DEEDEMEESTNRPR ddPTM_HeLa_Curcumin_4h_R1 2 IWSTVPTDEEDEMEESTNRPR 21 1 Q9GZL7 Q9GZL7 WDR12 Ribosome biogenesis protein WDR12 1 0 IWST(0.001)VPT(0.999)DEEDEMEESTNRPR;IWSTVPT(1)DEEDEMEESTNRPR ; 163.95 3.62E-08 53547000 2744.4 2662.7 2474.7 2472.75 3022.7 3412.4 2489.3 2788.9 3109.8 2784.4 TRUE FALSE FALSE 2527.177844 2892.851923 2566.414559 2462.518416 2986.656277 2704.629774 2559.143058 3639.222771 2768.66272 2881.157693 0.877139717 1.004058865 0.890758102 0.854697548 1.036616734 0.938730213 0.88823429 1.263111277 0.960954941 1 11.49243291 -4.25588218 24.80517071 0.939211059 1.263111432 0.736599815 0.058140467 229.0334868 1022280.99 0.008673246 0.101151893 5.55E-05 4.25588218 0.323900372 IYDLNKPEAEPK ddPTM_HeLa_Curcumin_4h_R1 1 IYDLNKPEAEPK 12 1 Q9Y3F4-2;Q9Y3F4 Q9Y3F4-2 STRAP Serine-threonine kinase receptor-associated protein 0 0 94.82 0.0071726 4923700 6891.2 5690.1 5582 6079.6 6620.4 6965.3 4897.7 4960.8 7086.2 6579.6 FALSE FALSE TRUE 6345.754248 6181.926889 5788.87383 6054.444226 6541.456054 5520.618265 5035.116281 6473.325083 6308.861589 6808.24061 0.932069621 0.908006524 0.850274566 0.889281765 0.960814464 0.810872967 0.739562035 0.950807331 0.926650797 1 12.73306631 -7.443208097 0.294704119 1.01777099 0.825432212 0.235101383 0.064419479 1.014463074 0.299659985 0.07084356 0.068149755 3.60E-08 7.443208097 -0.192338778 IYEDGDDDMKR ddPTM_HeLa_Curcumin_4h_R1 1 IYEDGDDDMKR 11 1 Q9HB71;Q9HB71-3 Q9HB71 CACYBP Calcyclin-binding protein 0 0 115.7 0.0069735 114340000 3431.5 2836.2 3261.5 3037.4 3100.1 3486 3025 2989 3597.2 3174.1 FALSE FALSE TRUE 3159.893154 3081.34849 3382.374059 3024.832044 3063.133332 2762.964305 3109.873359 3900.33234 3202.59616 3284.399739 0.962091525 0.93817706 1.029830206 0.920969518 0.932631097 0.841238742 0.946862016 1.187532776 0.975093294 1 11.68141401 -9.105539821 0.792763105 1.000945672 0.962878805 0 0.085934758 2.717758946 2.990920209 0.063093505 0.016977631 7.84E-10 9.105539821 -0.038066867 IYEFPET(ph)DDEEENKLVK ddPTM_HeLa_Curcumin_4h_R1 1 IYEFPETDDEEENKLVK 17 1 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181 G3V1Q4 7-Sep Septin-7 1 0 IYEFPET(1)DDEEENKLVK 85.493 0.0053987 28832000 3031.4 2291.7 2678.4 2629.5 2839.2 3093.8 2738.3 2185.1 3151.6 2319.3 TRUE FALSE FALSE 2791.461491 2489.784336 2777.66386 2618.619826 2805.344394 2452.111006 2815.129328 2851.326931 2805.877365 2399.895502 1.163159599 1.037455312 1.157410336 1.091139103 1.168944394 1.021757407 1.173021628 1.188104619 1.169166475 1 11.22875587 -9.431339279 0.987615496 0.994665099 1.125530144 0 0.075694785 0.4512541 0.733500525 0.044400698 0.009450697 3.70E-10 9.431339279 0.130865045 IYEFPETDDEEENKLVK ddPTM_HeLa_Curcumin_4h_R1 1 IYEFPETDDEEENKLVK 17 1 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181 G3V1Q4 7-Sep Septin-7 0 0 89.911 0.0037226 22612000 965.26 894.13 960.95 1002.9 1095.4 1151.9 1136.4 952.28 1296.2 1012.1 FALSE FALSE TRUE 888.8586525 971.414613 996.5636523 998.7502655 1082.33807 912.9829554 1168.284326 1242.625788 1154.010103 1047.2704 0.848738447 0.927568098 0.951581991 0.953669908 1.033484829 0.871773857 1.115551749 1.186537678 1.101921818 1 10.03241827 -4.637526114 4.897512421 0.935161175 1.169825142 0.497367531 0.073919178 0.090597757 3.39712291 0.009125302 0.036717025 2.30E-05 4.637526114 0.234663967 IYHLPDAES(ph)DEDEDFK ddPTM_HeLa_Curcumin_4h_R1 2 IYHLPDAESDEDEDFK 16 0 B5MCX3;Q15019;Q15019-3;Q15019-2;H7C2Y0 B5MCX3 2-Sep Septin-2 1 0 IYHLPDAES(1)DEDEDFK;IYHLPDAES(1)DEDEDFK ; 210.08 8.05E-11 16007400 4362.8 3576 4367.6 4507.4 4999.6 4396.8 4345.3 3866.3 4185.5 3762.3 TRUE FALSE FALSE 4017.479776 3885.093506 4529.467098 4488.749573 4939.983035 3484.854118 4467.217423 5045.117072 3726.361122 3893.039645 1.031964774 0.997958886 1.163478287 1.15301923 1.268926979 0.895149918 1.147488295 1.295932621 0.957185506 1 11.92668132 -6.761462712 25 1.014231059 1.147116847 0.355540083 0.10237668 0.592959689 634576.0579 0.01560365 0.021258207 1.73E-07 6.761462712 0.132885788 IYHLPDAES(ph)DEDEDFKEQTR ddPTM_HeLa_Curcumin_4h_R1 8 IYHLPDAESDEDEDFKEQTR 20 1 B5MCX3;Q15019;Q15019-3;Q15019-2;H7C2Y0 B5MCX3 2-Sep Septin-2 1 0 IYHLPDAES(0.999)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR;IYHLPDAES(1)DEDEDFKEQTR ;;;;;;; 115.02 6.47E-05 7593352000 22348.1 20214.1 21501.6 21315.16 21399.59 23153.1 20022.44 20827.7 25410.1 21341.9 TRUE FALSE FALSE 20579.2243 21961.31673 22298.46821 21226.96352 21144.41387 18350.88607 20584.21578 27177.96985 22622.6756 22083.52944 0.931881127 0.994465889 1.00973299 0.961212454 0.95747439 0.830976141 0.932107154 1.230689593 1.024413949 1 14.43068314 -4.25787267 24.94338762 0.959760485 1.230689699 0.704293572 0.052569683 143.2084385 1001466.533 0.007327788 0.071857722 5.52E-05 4.25787267 0.270929213 IYIDSNNNPER ddPTM_HeLa_Curcumin_4h_R1 2 IYIDSNNNPER 11 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 ; ; 142.83 2.29E-05 9158300 1497.78 1448.14 1107.99 1395.93 1360.62 1134.83 857.84 813.35 1488.9 1407.13 FALSE FALSE TRUE 1379.229133 1573.310769 1149.053084 1390.154012 1344.395495 899.4534658 881.9086816 1061.336671 1325.571395 1456.027663 0.947254759 1.080550053 0.789169817 0.954757967 0.923331012 0.617744765 0.605695004 0.728926172 0.910402617 1 10.50782205 -5.315499429 4.690688968 0.96525223 0.64542386 0.750540325 0.07685252 0.066215526 3.147431035 0.010456932 0.02453858 4.84E-06 5.315499429 -0.31982837 IYISLLK ddPTM_HeLa_Curcumin_4h_R1 1 IYISLLK 7 0 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12;O60716-25;O60716-26;O60716-27;O60716-29;O60716-32;O60716-28;O60716-31;O60716-30 O60716 CTNND1 Catenin delta-1 0 0 107.66 0.015435 2791700 710.31 388.47 552.29 578.07 416.8 1106.6 1014.4 713.26 565.14 477.96 FALSE FALSE TRUE 654.088214 422.0476158 572.7583532 575.6780995 411.8299322 877.078686 1042.861334 930.7296906 503.1455559 494.5690744 1.322541679 0.853364348 1.15809577 1.163999387 0.832704578 1.773419996 2.108626252 1.881900302 1.017341322 1 8.95002822 -5.112130883 4.795354929 1.116583427 1.984524047 0.863469242 0.158594674 0.063653342 2.251265085 0.024471109 0.06539412 7.72E-06 5.112130883 0.86794062 IYLEENPEKS(ph)ETIQDTDTQSLVGSPSTR ddPTM_HeLa_Curcumin_4h_R1 1 IYLEENPEKSETIQDTDTQSLVGSPSTR 28 1 E9PMR6;Q9NZN5-2;Q9NZN5 E9PMR6 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 0 IYLEENPEKS(0.49)ET(0.49)IQDT(0.003)DT(0.008)QS(0.008)LVGS(0.001)PST(0.001)R 73.574 7.21E-05 12979000 1545.9 1584.8 1418.4 1518.4 1415.6 2213.1 1896.2 2099.1 1784.3 1379.9 TRUE FALSE FALSE 1423.540384 1721.78305 1470.967152 1512.117263 1398.719895 1754.078113 1949.402269 2739.105927 1588.566754 1427.851422 0.996980751 1.205855892 1.03019623 1.059015833 0.979597648 1.228473835 1.36526969 1.918341001 1.112557462 1 10.47963015 -3.564838675 0.872954366 1.016018396 4.0925957 0.919576281 0.076582495 1.042087247 0.248084488 0.011071454 4.112356931 0.000272371 3.564838675 3.076577305 IYLYLTK ddPTM_HeLa_Curcumin_4h_R1 1 IYLYLTK 7 0 P41250 P41250 GARS Glycine--tRNA ligase 0 0 121.29 0.0094017 630150 1256.3 650.95 773.3 780.95 804.2 946.46 941.93 731.29 1184.9 973.21 FALSE FALSE TRUE 1156.862529 707.2152174 801.9591783 777.7186358 794.6104402 750.1535272 968.3580207 954.2569546 1054.919434 1007.028975 1.148787729 0.702278916 0.796361573 0.772290227 0.789064128 0.744917521 0.961598966 0.947596324 1.047556188 1 9.975889479 -7.266222246 24.99894045 1.070260874 0.815636744 0.646798238 0.084347289 199.1995195 1041168.127 0.016394124 0.019073237 5.42E-08 7.266222246 -0.254624129 IYNISGNGS(ph)PLADSK ddPTM_HeLa_Curcumin_4h_R1 2 IYNISGNGSPLADSK 15 0 Q53HL2 Q53HL2 CDCA8 Borealin 1 0 IY(0.033)NIS(0.06)GNGS(0.9)PLADS(0.006)K;IYNISGNGS(0.997)PLADS(0.003)K ; 252.38 6.39E-39 110112000 5844.2 4645.1 6124.8 6083.2 6147.3 8106.7 6253.1 3820.4 6727.4 4796.7 TRUE FALSE FALSE 5381.625403 5046.601746 6351.790476 6058.02933 6073.997462 6425.279039 6428.545157 4985.222373 5989.421051 4963.384968 1.084265161 1.016766134 1.279729563 1.220543917 1.223761103 1.294535701 1.295193743 1.0043997 1.206721036 1 12.27710864 -6.767152423 24.99922049 1.039176772 1.226751171 0.314060468 0.096806308 74.98074698 328101.9405 0.012750212 0.017015825 1.71E-07 6.767152423 0.187574399 IYNISGNGSPLADS(ph)K ddPTM_HeLa_Curcumin_4h_R1 2 IYNISGNGSPLADSK 15 0 Q53HL2 Q53HL2 CDCA8 Borealin 1 0 IYNISGNGS(0.002)PLADS(0.998)K;IYNIS(0.001)GNGS(0.484)PLADS(0.514)K ; 219.41 1.91E-14 100618000 8201.4 6535.3 7966.4 7697 8476.4 11490.1 8805.6 5802 7956.7 6308.1 TRUE FALSE FALSE 7552.250536 7100.182211 8261.641792 7665.151853 8375.324466 9106.92374 9052.661437 7571.003091 7083.869917 6527.306005 1.157024128 1.087766102 1.265704685 1.174320899 1.283121162 1.395204045 1.386890921 1.159897067 1.085267017 1 12.67227196 -7.198713852 0.314580757 0.987318607 1.354906369 0.578291031 0.080621719 0.627149419 0.194302081 0.070932565 0.085873841 6.33E-08 7.198713852 0.367587762 IYQY(ph)IQSR ddPTM_HeLa_Curcumin_4h_R1 2 IYQYIQSR 8 0 A0A2R8Y443;A0A2R8YDF3;A0A2R8Y6L5;A0A2R8Y6I6;Q13627-4;Q13627-3;Q13627-5;Q9Y463-2;Q9Y463-3;Q9Y463;Q13627-2;Q13627 A0A2R8Y443 DYRK1A;DYRK1B Dual specificity tyrosine-phosphorylation-regulated kinase 1A;Dual specificity tyrosine-phosphorylation-regulated kinase 1B 1 0 IYQY(1)IQSR;IYQY(1)IQSR ; 171.53 0.0057313 168693000 7322.4 6049.4 6089.4 6469.3 6189 8015 6394.7 4866.2 7925.4 6546.2 TRUE FALSE FALSE 6742.824313 6572.28318 6315.078521 6442.531751 6115.200217 6352.598652 6574.118072 6349.881979 7056.003448 6773.679963 0.995444773 0.970267745 0.932296559 0.95111251 0.902788477 0.937835665 0.97053863 0.937434602 1.041679484 1 12.72572411 -7.017536365 2.495871021 0.998030478 0.938868285 0.696016436 0.021145591 0.105035996 1.306051452 0.002761349 0.003572364 9.60E-08 7.017536365 -0.059162193 S(ph)VPTAYR ddPTM_HeLa_Curcumin_4h_R1 1 SVPTAYR 7 0 Q12872-2;Q12872 Q12872-2 SFSWAP "Splicing factor, suppressor of white-apricot homolog" 1 0 S(0.993)VPT(0.007)AYR 101.25 0.018973 3823400 511.97 276.65 480.2 543.9 515.35 738.65 548.31 1348.5 681.72 551.58 TRUE FALSE FALSE 471.4470343 300.5623933 497.9966344 541.6494859 509.2047878 585.4456637 563.6941029 1759.651442 606.9370216 570.7473639 0.826017016 0.526611969 0.87253427 0.949017937 0.892171949 1.025752725 0.987642061 3.083065387 1.06340749 1 9.156708481 -4.259506868 4.932527806 0.89435446 3.198348941 0.955223597 0.141608631 0.02518582 1.839338321 0.020046848 0.197702848 5.50E-05 4.259506868 2.303994481 up IYSFTDNAPS(ph)PSIGGSSR ddPTM_HeLa_Curcumin_4h_R1 2 IYSFTDNAPSPSIGGSSR 18 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 0 IYSFTDNAPS(0.979)PS(0.021)IGGSSR;IYSFTDNAPS(0.653)PS(0.346)IGGSSR ; 148.19 0.00014078 18532300 3210.9 2936.6 3691.9 3414.4 3589.1 4347.8 4537.5 1897.62 3374.2 2758.3 TRUE FALSE FALSE 2956.753877 3190.426619 3828.725062 3400.272117 3546.302327 3446.01727 4664.810038 2476.195602 3004.058702 2854.15072 1.035948752 1.117819951 1.341458612 1.191342873 1.242507027 1.207370461 1.63439513 0.867577029 1.052522798 1 11.47884581 -7.004587552 3.324233313 1.017562783 1.260310653 0.233723646 0.176602951 0.211330547 4.892447029 0.026412048 0.034096757 9.89E-08 7.004587552 0.24274787 IYSSDS(ph)DEGSEEDKAQR ddPTM_HeLa_Curcumin_4h_R1 1 IYSSDSDEGSEEDKAQR 17 1 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 0 IYS(0.09)S(0.409)DS(0.498)DEGS(0.002)EEDKAQR 66.777 0.010126 10636000 1560.4 1156.6 1580.5 1713.3 1615 1529.5 1047.5 1158 1740.8 1357.2 TRUE FALSE FALSE 1436.892693 1256.57135 1639.07472 1706.210819 1595.74218 1212.264459 1076.890031 1511.068869 1549.838595 1404.362599 1.023163601 0.894762757 1.167130712 1.2149361 1.136275048 0.86321329 0.766817652 1.075981994 1.103588629 1 10.45569976 -5.241945726 24.26834141 1.037174776 0.888485623 0.280429753 0.116264976 623.9534893 776779.5659 0.016498145 0.04198421 5.73E-06 5.241945726 -0.148689153 IYVDDGLISLQVK ddPTM_HeLa_Curcumin_4h_R1 1 IYVDDGLISLQVK 13 0 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BQ34 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 201.6 1.65E-29 0 919.71 811.99 883.32 942.86 896.79 1367.7 820.48 887.8 1051.9 815.33 FALSE FALSE TRUE 846.913983 882.1747974 916.0566162 938.9586951 886.096365 1084.023603 843.5004606 1158.486133 936.5092017 843.6626568 1.003853823 1.045648744 1.085809131 1.112955146 1.050297009 1.284901725 0.999807748 1.373162749 1.110051742 1 9.720522434 -1 0.266917843 0.989646983 2.999635206 0.384658156 0.093982575 25.88013675 0.327571808 0.036472079 24.17992015 0.1 1 2.009988223 IYVGNLPPDIR ddPTM_HeLa_Curcumin_4h_R1 1 IYVGNLPPDIR 11 0 J3KTL2;Q07955;Q07955-3;Q07955-2;J3QQV5;J3KSW7 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 0 96.331 0.014225 957950 704.55 437.85 413.62 486.22 507.01 816.33 643.68 782.16 823.38 514.12 FALSE FALSE TRUE 648.7841241 475.695803 428.9491211 484.2081505 500.9642369 647.0139561 661.7399284 1020.636983 733.057274 531.9856317 1.219551968 0.894189193 0.806317117 0.910190279 0.941687533 1.216224495 1.243905641 1.918542386 1.377964423 1 9.055243471 -3.993349107 1.417185653 1.046028625 2.811949415 0.719019692 0.164882094 0.908768661 0.993007788 0.022976627 2.723212761 0.000101543 3.993349107 1.765920791 K(ac)APSKRPPISDSEELSAK ddPTM_HeLa_Curcumin_4h_R1 1 KAPSKRPPISDSEELSAK 18 3 P42568-2;P42568 P42568-2 MLLT3 Protein AF-9 0 1 K(0.5)APSK(0.5)RPPISDSEELSAK 51.798 0.019815 11703000 7748.1 7419.9 10143 8342.7 6329.7 8382.9 4552 2678.7 7741.5 6962 FALSE TRUE FALSE 7134.829709 8061.243094 10518.9085 8308.180118 6254.222462 6644.192045 4679.716869 3495.423299 6892.276818 7203.928982 0.990408113 1.119006464 1.460162715 1.153284567 0.868168256 0.922301158 0.649606191 0.485210683 0.956738585 1 12.81456824 -4.693489808 1.348315255 1.048301276 0.429477962 0.65262665 0.149912323 0.367053615 0.957525597 0.024579727 0.249410679 2.03E-05 4.693489808 -0.618823314 K(ac)AVTK(ac)AQK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 KAVTKAQKK 9 3 P58876;P62807;P57053;O60814;Q16778;P06899;Q8N257;Q93079;U3KQK0;Q99877;Q99880 P58876;P62807;Q16778;Q8N257;Q93079;U3KQK0;Q99880 HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BL Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-L 0 3 ; K(1)AVTK(1)AQK(1)K;K(1)AVTK(1)AQK(1)K 141.93 3.74E-05 54761000 17430.4 5689.6 12027.2 8541.6 12868.5 12653 9905.3 5991.1 10671.8 13434.5 FALSE TRUE FALSE 16050.76545 6181.383672 12472.93861 8506.257122 12715.05154 10028.62517 10183.21606 7817.75881 9501.13024 13901.34788 1.154619364 0.444660743 0.897246708 0.611901608 0.914663215 0.72141387 0.732534438 0.562374158 0.683468274 1 13.76293715 -7.281381963 24.96712562 1.073014709 0.71277476 0.187729464 0.185383859 377.3803317 472460.2989 0.022693927 0.025968829 5.23E-08 7.281381963 -0.360239949 K(ac)AVTK(ac)VQKK ddPTM_HeLa_Curcumin_4h_R1 1 KAVTKVQKK 9 3 Q5QNW6;Q5QNW6-2 Q5QNW6 HIST2H2BF Histone H2B type 2-F 0 2 K(1)AVTK(1)VQKK 89.9 0.0015726 0 5680.5 3877.1 4435.5 4290.8 3748 5545 4294.7 2393.4 5678.9 5564.8 FALSE TRUE FALSE 5230.882431 4212.219248 4599.883532 4273.045807 3703.307548 4394.904495 4415.197723 3123.136642 5055.938878 5758.176386 0.908426919 0.731519663 0.798843805 0.742083174 0.643138956 0.763245896 0.766770142 0.542382941 0.878045155 1 12.49139627 -7.211208313 0.551906632 0.994182388 0.673499557 0.631875252 0.07535044 0.245183775 0.170090264 0.022078761 0.027269311 6.15E-08 7.211208313 -0.320682831 K(ac)EVLNMLK ddPTM_HeLa_Curcumin_4h_R1 1 KEVLNMLK 8 1 Q92896;Q92896-3;Q92896-2 Q92896 GLG1 Golgi apparatus protein 1 0 1 K(1)EVLNMLK 58.815 0.016577 2713800 1395.5 1848 2152.4 1815.8 1062.4 1103.4 1468.5 1167.8 1660.5 2996 FALSE TRUE FALSE 1285.044702 2007.732885 2232.169837 1808.286701 1049.731574 874.5424021 1509.702158 1523.856844 1478.347304 3100.110777 0.414515737 0.647632627 0.720029056 0.583297447 0.338610988 0.282100372 0.486983294 0.491549159 0.476869187 1 11.59810405 -13.52287874 0.254523565 4.409073687 0.431660772 0 0.209228287 20.47562743 0.27178278 35.09346196 0.080343906 3.00E-14 13.52287874 -3.977412915 K(ac)FDQLLAEEK ddPTM_HeLa_Curcumin_4h_R1 2 KFDQLLAEEK 10 1 P35579;P35579-2;P35580;P35580-5;P35580-2;P35580-3;P35580-4;P35749-4;P35749-3;P35749;P35749-2;Q7Z406;Q7Z406-6;Q7Z406-2;A0A0C4DFM8;A1L2Z2 P35579;P35580;P35749-4;Q7Z406 MYH9;MYH10;MYH11;MYH14 Myosin-9;Myosin-10;Myosin-11;Myosin-14 0 1 ; K(1)FDQLLAEEK;K(1)FDQLLAEEK 154.15 4.85E-09 2711490 1227.15 1390.22 1046.96 1145.58 2080.07 2353.76 2265.22 1527.85 2666.08 1104.51 FALSE TRUE FALSE 1130.019783 1510.384422 1085.761259 1140.839893 2055.266524 1865.563644 2328.775977 1993.684432 2373.617694 1142.89164 0.988737465 1.321546478 0.950012425 0.998204776 1.798303926 1.632318916 2.037617474 1.744421222 2.076852792 1 10.15847291 -5.760131987 24.83218418 1.018294224 1.807708796 0.299510274 0.361454816 7.075537097 134384.9 0.01930966 0.036982474 1.74E-06 5.760131987 0.789414572 K(ac)FGDPVVQSDMK ddPTM_HeLa_Curcumin_4h_R1 2 KFGDPVVQSDMK 12 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 1 ; K(1)FGDPVVQSDMK;K(1)FGDPVVQSDMK 134.49 0.0001046 6663400 4602.2 5123.9 3886.9 3650.1 8234.1 10741.9 6775.3 7053.3 9759.6 3838.3 FALSE TRUE FALSE 4237.931014 5566.787084 4030.951933 3634.996853 8135.913735 8513.908854 6965.396683 9203.818701 8688.996297 3971.680639 1.067037206 1.401620017 1.014923479 0.915228888 2.048481354 2.143653941 1.753765551 2.317361222 2.187737909 1 11.95553391 -5.756518355 24.99999999 1.054552698 2.049086339 0.444154952 0.399600714 27.78783029 141167.2675 0.024649319 0.048079763 1.75E-06 5.756518355 0.994533641 K(ac)FGNPGEK ddPTM_HeLa_Curcumin_4h_R1 2 KFGNPGEK 8 1 P17844-2;P17844;J3KTA4;J3QRQ7;J3QR02;J3KRX8;J3KTQ4;X6RLV5;J3QKN9 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 1 ; K(1)FGNPGEK;K(1)FGNPGEK 104.01 0.0033118 35077000 9644.2 9726.7 10330.5 8454.4 8588.5 12156 9187.4 11086.6 10522.5 9118 FALSE TRUE FALSE 8880.851393 10567.43261 10713.35742 8419.417933 8486.087747 9634.708574 9445.173717 14466.8533 9368.208076 9434.849821 0.941281691 1.120042482 1.135509056 0.892374345 0.899440681 1.021183035 1.00109423 1.533342192 0.99293664 1 13.20378384 -4.2606563 5.754963763 0.986421916 1.550669437 0.809026139 0.077438945 0.044836787 6.356017876 0.01111833 0.098608844 5.49E-05 4.2606563 0.56424752 K(ac)FGVLSDNFK ddPTM_HeLa_Curcumin_4h_R1 2 KFGVLSDNFK 10 1 Q06203 Q06203 PPAT Amidophosphoribosyltransferase 0 1 ; K(1)FGVLSDNFK;K(1)FGVLSDNFK 85.29 0.0053378 624740 711.551 759.18 513.59 509.21 643.61 701.33 599.58 546.24 542.76 617.955 FALSE TRUE FALSE 655.2309875 824.8001364 532.6240972 507.1030239 635.9353711 555.8662524 616.4026011 712.7860614 483.2205859 639.4288903 1.02471283 1.289901268 0.832968459 0.793056166 0.994536501 0.869316762 0.963989289 1.114722954 0.755706527 1 9.320640118 K(ac)GATPGKALVATPGK ddPTM_HeLa_Curcumin_4h_R1 2 KGATPGKALVATPGK 15 2 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 ; K(0.903)GATPGK(0.097)ALVATPGK;K(0.898)GATPGK(0.102)ALVATPGK 145.69 0.00035726 31653000 17084.6 14956.4 16716.8 15942.2 16652 19403.4 21080 21973 18069.4 14485.5 FALSE TRUE FALSE 15732.33588 16249.16457 17336.33931 15876.2354 16453.43578 15378.91612 21671.44807 28672.46655 16087.23203 14988.87005 1.049601193 1.084082024 1.156614158 1.059201618 1.097710216 1.02602238 1.44583601 1.912917148 1.073278504 1 13.87160401 -4.426083297 2.039517645 1.043743897 2.016141343 0.962935899 0.051742581 0.068358801 0.393851359 0.008170144 0.107827405 3.75E-05 4.426083297 0.972397447 K(ac)GSK(ac)K(ac)AITK ddPTM_HeLa_Curcumin_4h_R1 1 KGSKKAITK 9 3 P33778 P33778 HIST1H2BB Histone H2B type 1-B 0 3 K(1)GSK(1)K(1)AITK 115.29 0.0079475 7632800 4221.8 2938.9 3755.1 2605 3580.5 4525.9 3502.4 1676.9 3537.1 3174.7 FALSE TRUE FALSE 3887.640075 3192.925421 3894.267309 2594.2212 3537.804876 3587.177323 3600.667918 2188.179091 3149.088979 3285.020589 1.18344466 0.971965117 1.185462071 0.789712311 1.076950595 1.091980164 1.096086865 0.666108181 0.958620774 1 11.6816867 -6.289515621 24.98961487 1.085142051 0.968196142 0.109721371 0.149135185 1121.536401 998235.282 0.022182931 0.033889016 5.13E-07 6.289515621 -0.116945909 K(ac)GYMIVK ddPTM_HeLa_Curcumin_4h_R1 1 KGYMIVK 7 1 F8W8T1;P20591-2;P20591;P20592 F8W8T1 MX1;MX2 "Interferon-induced GTP-binding protein Mx1;Interferon-induced GTP-binding protein Mx1, N-terminally processed;Interferon-induced GTP-binding protein Mx2" 0 1 K(1)GYMIVK 70.912 0.018878 0 1624.6 1378.7 1680.3 1499.3 1440.9 238.11 658.12 796.85 1395.1 1416.7 FALSE TRUE FALSE 1496.011196 1497.868685 1742.573396 1493.096294 1423.718209 188.7233019 676.585076 1039.805897 1242.06102 1465.93022 1.02052006 1.021787166 1.188715106 1.018531629 0.971204625 0.128739622 0.461539756 0.709314729 0.847285228 1 10.51760072 -5.360469912 6.995252402 1.024719691 0.437851156 0.75203385 0.151700749 0.078844053 4.810392922 0.019260343 0.043318676 4.36E-06 5.360469912 -0.586868535 K(ac)HEAFESDLAAHQDR ddPTM_HeLa_Curcumin_4h_R1 2 KHEAFESDLAAHQDR 15 1 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75;A0A494C1A0;P35609-2;P35609;H7C5W8;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2 0 1 ; K(1)HEAFESDLAAHQDR;K(1)HEAFESDLAAHQDR 95.755 0.00099098 4732100 1084.07 1268.52 1333.4 1254.72 2701.9 3207.6 2226.9 1944.75 2122.3 1360.88 FALSE TRUE FALSE 998.2647156 1378.165216 1382.816977 1249.528301 2669.681607 2542.307603 2289.380821 2537.695322 1889.489 1408.170479 0.708908993 0.978692024 0.981995432 0.887341639 1.89585114 1.8053976 1.625783849 1.802122229 1.341804155 1 10.45960629 -5.766534307 24.99966447 0.880523621 1.772760475 0.823380339 0.177529395 24.20800971 118783.9854 0.019478396 0.036103737 1.71E-06 5.766534307 0.892236854 K(ac)K(ac)FMGTELNGK ddPTM_HeLa_Curcumin_4h_R1 1 KKFMGTELNGK 11 2 A0A286YF22;A0A2C9F2M7;O43175;A0A286YFL2;A0A286YFA2;A0A286YFM8;A0A286YF78;A0A286YFE1 A0A286YF22 PHGDH D-3-phosphoglycerate dehydrogenase 0 2 K(1)K(1)FMGTELNGK 60.102 0.013772 0 211.35 0 0 91.292 0 80.876 74.646 0 206.62 0 FALSE TRUE FALSE 194.6214245 0 0 90.91425789 0 64.10140594 76.74036586 0 183.9543029 0 0 K(ac)LCVFK ddPTM_HeLa_Curcumin_4h_R1 1 KLCVFK 6 1 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 1 K(1)LCVFK 67.035 0.019709 0 1049.1 1269.1 886.71 825.65 1933.9 1946.3 1706.5 1493.2 2321.5 1160.9 FALSE TRUE FALSE 966.062628 1378.795349 919.5722526 822.2336791 1910.839506 1542.615441 1754.379797 1948.469806 2066.837258 1201.241189 0.804220366 1.147808918 0.765518417 0.684486752 1.590720934 1.284184604 1.460472563 1.622047116 1.72058474 1 10.23031013 -5.755496223 24.99999134 0.899640332 1.472638131 0.330122836 0.29848348 50.70503232 213289.3898 0.022085523 0.04325812 1.76E-06 5.755496223 0.572997799 K(ac)LDEAVAEAHLGK ddPTM_HeLa_Curcumin_4h_R1 2 KLDEAVAEAHLGK 13 1 P23526-2;P23526 P23526-2 AHCY Adenosylhomocysteinase 0 1 ; K(1)LDEAVAEAHLGK;K(1)LDEAVAEAHLGK 124.81 0.00028026 8610600 5317.7 7111.2 5490.7 4948.5 10311.1 14284.6 9809.7 9684.8 13858.5 5711.2 FALSE TRUE FALSE 4896.798434 7725.860441 5694.190172 4928.024418 10188.14687 11321.81294 10084.93378 12637.65094 12338.25722 5909.663775 0.828608635 1.307326565 0.963538771 0.83389252 1.723980797 1.915813381 1.706515661 2.138472072 2.087810355 1 12.52886034 -5.688871479 4.767757789 0.947753206 1.88431202 0.364832338 0.395595966 0.049794951 2.119163836 0.024051091 0.048635994 2.05E-06 5.688871479 0.936558815 K(ac)LDPGSEETQTLVR ddPTM_HeLa_Curcumin_4h_R1 2 KLDPGSEETQTLVR 14 1 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 1 ; K(1)LDPGSEETQTLVR;K(1)LDPGSEETQTLVR 194.98 4.36E-13 16267200 2299.09 3027.3 2611.3 2111.3 4630.4 5800.8 4378.7 4143 5609.1 2205.72 FALSE TRUE FALSE 2117.114601 3288.966323 2708.077075 2102.564 4575.185504 4597.648692 4501.554537 5406.181628 4993.795763 2282.368606 0.927595392 1.441032055 1.186520472 0.921220172 2.004577829 2.014419879 1.97231706 2.36867157 2.187988281 1 11.15631609 -5.740158471 7.542333867 1.019974861 2.080194447 0.412352093 0.411368205 0.042127732 10.1793645 0.027909825 0.054904969 1.82E-06 5.740158471 1.060219585 K(ac)LEAAEER ddPTM_HeLa_Curcumin_4h_R1 2 KLEAAEER 8 1 P16949;P16949-2;A2A2D0;E5RIR6;E7EVN3;Q9H169-3;Q9H169;Q9H169-4;Q9H169-2;E5RGX5;Q93045;Q93045-2 P16949;E5RGX5 STMN1;STMN4;STMN2 Stathmin;Stathmin-4;Stathmin-2 0 1 ; K(1)LEAAEER;K(1)LEAAEER 107.79 0.0026053 19289600 10565.5 11911.3 8742.9 9085.3 10348.5 15711.9 11014.1 12941.6 11913.4 9335.9 FALSE TRUE FALSE 9729.229526 12940.8597 9066.919565 9047.707436 10225.1009 12453.07483 11323.126 16887.43426 10606.52983 9660.32183 1.007133064 1.33958888 0.938573241 0.936584474 1.058463794 1.289095234 1.172127203 1.748123361 1.097947875 1 13.23785554 -1 0.756849442 1.021686181 132.4534188 0.705354965 0.128109567 136.0180597 0.535553937 0.01965229 30534.76809 0.1 1 131.4317326 K(ac)LESTESR ddPTM_HeLa_Curcumin_4h_R1 1 KLESTESR 8 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 1 K(1)LESTESR 91.087 0.0074259 2101600 1151.8 717.33 1037.2 1114.1 1056.4 1199.2 870.01 878.91 1149.5 980.12 FALSE TRUE FALSE 1060.633815 779.3328088 1075.639544 1109.490149 1043.80312 950.4724022 894.4201391 1146.885613 1023.402726 1014.179097 1.045805241 0.768437065 1.060601177 1.093978522 1.029209854 0.93718398 0.881915375 1.130851165 1.009094675 1 9.98609673 K(ac)LEVNEAELLR ddPTM_HeLa_Curcumin_4h_R1 1 KLEVNEAELLR 11 1 Q6NZI2 Q6NZI2 PTRF Polymerase I and transcript release factor 0 1 K(1)LEVNEAELLR 96.64 0.0046877 2567700 430.3 578.61 623.46 589.23 969.37 1219.4 812.49 1012.5 1098 466.19 FALSE TRUE FALSE 396.2413009 628.6224702 646.5659761 586.7919224 957.8108959 966.4826945 835.2862827 1321.206589 977.5521471 482.3900678 0.821412644 1.303141404 1.340338492 1.216426211 1.985552688 2.003529424 1.731557796 2.73887602 2.026476522 1 8.914056393 -5.265168157 0.499460818 0.898055453 2.730481809 0.402017476 0.428727646 0.549728339 0.167592655 0.056436726 0.497001136 5.43E-06 5.265168157 1.832426356 K(ac)LFEELVR ddPTM_HeLa_Curcumin_4h_R1 1 KLFEELVR 8 1 P14618-2;H3BTN5;H3BR70 P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 1 K(1)LFEELVR 78.934 0.015548 395560 153.77 140.68 57.016 121.09 158.78 345.04 181.82 193.78 177.14 0 FALSE TRUE FALSE 141.5989422 152.8397523 59.12906312 120.5889617 156.8866522 273.4748146 186.9213799 252.8626299 157.7081852 0 0 AHPEVNGDTK(ac)WHSFK ddPTM_HeLa_Curcumin_4h_R1 1 AHPEVNGDTKWHSFK 15 1 D6RE87;E7EPB1;E7EQS8;Q6N021-2;Q6N021-3;Q6N021 D6RE87 TET2 Methylcytosine dioxygenase TET2 0 1 AHPEVNGDTK(1)WHSFK 89.747 0.0024496 6251800 8214.2 7415.4 8205.2 7173.4 7478.3 9218.5 4439.4 1306 8679.1 6656.4 FALSE TRUE FALSE 7564.037402 8056.354134 8509.29193 7143.718372 7389.126157 7306.479186 4563.957616 1704.193388 7727.024444 6887.709405 1.098193457 1.169671027 1.235431321 1.037168956 1.072798767 1.060799572 0.662623428 0.247425274 1.121856918 1 12.74980856 -4.466957836 2.027150753 1.074061241 0.171788822 0.938488392 0.069737363 0.095324328 0.569825945 0.011601262 0.134923631 3.41E-05 4.466957836 -0.902272419 down K(ac)LKDVLLQVDDERR ddPTM_HeLa_Curcumin_4h_R1 1 KLKDVLLQVDDERR 14 3 P35579;P35579-2 P35579 MYH9 Myosin-9 0 1 K(0.5)LK(0.5)DVLLQVDDERR 63.181 0.01624 1069400 1448.5 1005.9 1303.1 1315.4 1090.2 1540.8 1273.4 1276 1870.7 1060.1 FALSE TRUE FALSE 1333.849697 1092.845514 1351.394032 1309.957223 1077.200077 1221.220712 1309.128177 1665.046526 1665.48889 1096.938396 1.215975028 0.996268813 1.231968939 1.194193975 0.982005991 1.113299266 1.193438193 1.517903405 1.518306676 1 10.09926679 K(ac)LLEDYK(ac)VPK ddPTM_HeLa_Curcumin_4h_R1 1 KLLEDYKVPK 10 2 B2WTI3;B2WTI4;K7EJU9;Q6NYC1-2;Q6NYC1;Q6NYC1-3 B2WTI3 JMJD6 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 0 2 K(1)LLEDYK(1)VPK 69.979 0.012239 42480000 18710 13884 14960 14893 15834 18518 15270 14803 17171 14051 FALSE TRUE FALSE 17229.08376 15084.07109 15514.43076 14831.37671 15645.18989 14677.15806 15698.4351 19316.36656 15287.38426 14539.2712 1.185003259 1.037470922 1.067070732 1.020090794 1.076064245 1.009483753 1.07972641 1.32856498 1.051454646 1 13.82766733 -9.678838553 1.552004703 1.000158673 1.105280076 0.087308474 0.090771445 0.612005439 2.661423883 0.065171876 0.01462325 2.09E-10 9.678838553 0.105121402 K(ac)LLEGEEER ddPTM_HeLa_Curcumin_4h_R1 2 KLLEGEEER 9 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8;P20700;E9PBF6;Q03252 P02545;P02545-2;P20700;Q03252 LMNA;LMNB1;LMNB2 Prelamin-A/C;Lamin-A/C;Lamin-B1;Lamin-B2 0 1 ; K(1)LLEGEEER;K(1)LLEGEEER 109.83 0.0012392 21974000 3232.5 3326.6 2957.9 3083.2 3947.9 5358.6 4441.6 3668.6 5196.6 2878.1 FALSE TRUE FALSE 2976.644214 3614.136481 3067.522376 3070.442535 3900.823871 4247.165956 4566.219342 4787.139252 4626.545981 2978.113761 0.999506551 1.213565623 1.030021894 1.031002434 1.309830377 1.426126165 1.533258871 1.607440023 1.553515531 1 11.54018315 -5.323626807 0.941675097 1.011540069 1.633021907 0.382491216 0.184871417 0.140713609 0.207007409 0.011542767 0.06095442 4.75E-06 5.323626807 0.621481838 K(ac)LNKEELPVIPK ddPTM_HeLa_Curcumin_4h_R1 2 KLNKEELPVIPK 12 2 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 0 1 ; K(0.995)LNK(0.005)EELPVIPK;K(0.851)LNK(0.149)EELPVIPK 95.273 0.0032534 4409000 6093.8 6602.3 5345.1 4906.2 6371.6 9208.5 6456.1 6422.6 9450.3 5889.3 FALSE TRUE FALSE 5611.4693 7172.973393 5543.194108 4885.899444 6295.622831 7298.553299 6637.24079 8380.821174 8413.625733 6093.952737 0.920825865 1.177064166 0.909622104 0.801761952 1.033093479 1.197671465 1.089151997 1.375268489 1.380651623 1 12.5731626 -4.109285516 0.813237064 0.966142871 1.651151265 0.173817159 0.167745225 1.638279068 0.664596254 0.016873 1.067866913 7.78E-05 4.109285516 0.685008394 ADEK(ac)PKEGVK(ac)TENNDHINLK ddPTM_HeLa_Curcumin_4h_R1 1 ADEKPKEGVKTENNDHINLK 20 3 P61956-2;P61956 P61956-2 SUMO2 Small ubiquitin-related modifier 2 0 2 ADEK(0.955)PK(0.05)EGVK(0.995)TENNDHINLK 98.227 0.00030329 29127000 6196.6 3935.3 4466.1 5006.3 4042.4 8389.3 9542.5 15030 6591.1 4595.2 FALSE TRUE FALSE 5706.132571 4275.449797 4631.617595 4985.585257 3994.19702 6649.264613 9810.236868 19612.57781 5868.07282 4754.882858 1.200057444 0.899170374 0.974076067 1.04851905 0.840020068 1.39840766 2.063192125 4.124723657 1.234115118 1 12.21519408 -4.178925809 1.502307988 1.054167122 5.775895431 0.980882027 0.130438622 0.127278865 0.224193109 0.019414973 0.940487989 6.62E-05 4.178925809 4.72172831 up K(ac)LVESLPQEIK ddPTM_HeLa_Curcumin_4h_R1 2 KLVESLPQEIK 11 1 B4DLN1;P52815 B4DLN1 MRPL12 "39S ribosomal protein L12, mitochondrial" 0 1 ; K(1)LVESLPQEIK;K(1)LVESLPQEIK 155.97 7.13E-08 3071330 2867.23 3073.98 2964.9 3065 3560.3 5143.8 3668.8 3757.54 4446.5 2845.07 FALSE TRUE FALSE 2640.28572 3339.681134 3074.781802 3052.317842 3517.845748 4076.917897 3771.736654 4903.196648 3958.730075 2943.935971 0.896855688 1.134427232 1.044445882 1.036815295 1.19494642 1.384852775 1.281188413 1.665524216 1.344706581 1 11.52353058 -3.650360402 0.420479413 0.950100514 2.513745192 0.531443636 0.14767644 1.975992212 0.162961975 0.020676159 1.725598712 0.000223686 3.650360402 1.563644678 K(ac)LYDIDVAK ddPTM_HeLa_Curcumin_4h_R1 1 KLYDIDVAK 9 1 K7EMA7;H7BY10;K7EJV9;K7ERT8;A8MUS3;P62750 K7EMA7 RPL23A 60S ribosomal protein L23a 0 1 K(1)LYDIDVAK 81.017 0.013618 2453500 1153.8 1726.9 1273.4 1055.5 2323.8 3113.7 2288.9 2207.8 2905 1343.4 FALSE TRUE FALSE 1062.475513 1876.165541 1320.593324 1051.132621 2296.090203 2467.883521 2353.120374 2880.948057 2586.328768 1390.08305 0.764325205 1.349678741 0.950010378 0.756165339 1.651764765 1.775349697 1.692791214 2.072500673 1.860557013 1 10.44095536 -5.673159511 4.891582578 0.921689486 1.811552136 0.431099169 0.348624909 0.061634977 2.541315685 0.028071347 0.056874053 2.12E-06 5.673159511 0.889862649 K(ac)LYVSNLGIGHTR ddPTM_HeLa_Curcumin_4h_R1 2 KLYVSNLGIGHTR 13 1 Q06203;D6RCC8 Q06203 PPAT Amidophosphoribosyltransferase 0 1 ; K(1)LYVSNLGIGHTR;K(1)LYVSNLGIGHTR 145.1 8.36E-05 14442700 3132.4 2195.54 1965.61 1782.25 3150.8 8073.6 3493.6 3629.1 3587.8 2666.9 FALSE TRUE FALSE 2884.467235 2385.312694 2038.457236 1774.875522 3113.228768 6399.044352 3591.621013 4735.595884 3194.227316 2759.574576 1.045257939 0.864376964 0.738685322 0.643169979 1.12815533 2.318851756 1.301512575 1.716060122 1.157507155 1 11.43023016 -5.499364541 23.38686092 0.958554538 1.729816445 0.670523983 0.271310283 152.3164114 151490.9321 0.036283645 0.080571817 3.17E-06 5.499364541 0.771261907 AGGTEIGK(ac)TLAEK ddPTM_HeLa_Curcumin_4h_R1 2 AGGTEIGKTLAEK 13 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 0 1 ; AGGTEIGK(1)TLAEK;AGGTEIGK(1)TLAEK 243.4 3.09E-49 25198000 7520.9 6347.2 7036.8 6039.7 5571.7 8924.5 7560.7 10279.5 7441.7 5844.6 FALSE TRUE FALSE 6925.612829 6895.823685 7297.589998 6014.709322 5505.261116 7073.4581 7772.832893 13413.67223 6625.364128 6047.699415 1.145164856 1.140239157 1.206672074 0.994545018 0.91030667 1.169611387 1.285254501 2.217979319 1.095518093 1 12.56217072 -4.174401632 2.045771106 1.072626451 2.726984101 0.939427109 0.086155044 0.174562662 0.647723648 0.013575814 0.577649468 6.69E-05 4.174401632 1.654357651 up K(ac)NNK(ac)K(ac)TNK ddPTM_HeLa_Curcumin_4h_R1 2 KNNKKTNK 8 3 Q92793;Q92793-2 Q92793 CREBBP CREB-binding protein 0 3 ; K(1)NNK(1)K(1)TNK;K(1)NNK(1)K(1)TNK 132.01 0.0043607 4489800 2103.42 1662.33 1655.14 1390.17 1730.59 1963.25 1196.37 568.04 1601.55 1404.32 FALSE TRUE FALSE 1936.932087 1806.014398 1716.480944 1384.417845 1709.953845 1556.04982 1229.936922 741.2327811 1425.863972 1453.120015 1.332947084 1.242852881 1.18123825 0.952720925 1.176746467 1.070833657 0.846411108 0.510097427 0.981243088 1 10.50493815 -4.104790219 1.049776471 1.159475254 4.73E-14 0.723935948 0.117064335 1.035559173 0.722297001 0.021266098 1.443192105 7.86E-05 4.104790219 -1.159475254 K(ac)NNK(ac)K(ac)TSK ddPTM_HeLa_Curcumin_4h_R1 1 KNNKKTSK 8 3 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 0 3 K(1)NNK(1)K(1)TSK 112.71 0.018118 1379500 618.89 613.08 570.48 499.75 661.9 738.25 643.9 433.91 518.31 596.07 FALSE TRUE FALSE 569.9042035 666.0719034 591.6224906 497.6821669 654.0072748 585.1286282 661.966101 566.2071615 461.4526897 616.7833881 0.923994087 1.079912196 0.959206266 0.806899434 1.060351636 0.948677671 1.073255399 0.918000018 0.748160049 1 9.268620099 K(ac)QLATK(ac)AAR ddPTM_HeLa_Curcumin_4h_R1 1 KQLATKAAR 9 2 K7EMV3;K7EP01;A0A590UJJ6;B4DEB1;K7EK07;K7ES00;P84243;Q6NXT2;Q5TEC6;Q71DI3;P68431 K7EMV3;Q5TEC6 H3F3B;H3F3A;H3F3C;HIST2H3PS2;HIST2H3A;HIST1H3A Histone H3;Histone H3.3;Histone H3.3C;Histone H3.2;Histone H3.1 0 2 K(1)QLATK(1)AAR 160.36 4.81E-11 57721000 4110.2 1890 3132.7 2601.9 3105.1 9239.9 5278.7 1532.1 2767.3 2499.9 FALSE TRUE FALSE 3784.873333 2053.363178 3248.800618 2591.134027 3068.073711 7323.440585 5426.806115 1999.230237 2463.734113 2586.771339 1.463165018 0.793793849 1.255928798 1.001686538 1.186062975 2.831112466 2.097907161 0.772867013 0.952435987 1 11.33693682 -5.450457962 24.99998769 1.174569823 1.935063796 0.343171608 0.502466522 127.5789366 44040.27194 0.069259228 0.154868317 3.54E-06 5.450457962 0.760493973 K(ac)RCNVSDEMK ddPTM_HeLa_Curcumin_4h_R1 1 KRCNVSDEMK 10 2 Q13023 Q13023 AKAP6 A-kinase anchor protein 6 0 1 K(1)RCNVSDEMK 82.287 0.013359 0 72.899 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 67.12896723 0 0 0 0 0 0 0 0 0 0 K(ac)RELDMK(ac)EK ddPTM_HeLa_Curcumin_4h_R1 1 KRELDMKEK 9 3 Q96SB8;Q96SB8-2 Q96SB8 SMC6 Structural maintenance of chromosomes protein 6 0 2 K(1)RELDMK(1)EK 64.711 0.009479 3912600 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 K(ac)SAPATGGVK(ac)KPHR ddPTM_HeLa_Curcumin_4h_R1 1 KSAPATGGVKKPHR 14 3 Q5TEC6;Q71DI3;P68431;Q16695 Q5TEC6 HIST2H3PS2;HIST2H3A;HIST1H3A;HIST3H3 Histone H3;Histone H3.2;Histone H3.1;Histone H3.1t 0 2 K(1)SAPATGGVK(0.728)K(0.272)PHR 46.66 0.018328 4573400 3907.2 3111.8 4291.5 3972.7 3069.1 7300.4 6783.7 5133.7 4319.9 3949.4 FALSE TRUE FALSE 3597.940997 3380.770126 4450.546765 3956.26202 3032.502987 5786.214748 6974.032365 6698.941497 3846.017778 4086.641356 0.880415158 0.827273507 1.089047552 0.968096213 0.742052635 1.415885135 1.706543774 1.639229116 0.941119478 1 11.99669992 -5.070488678 3.981085023 0.93563379 1.658508372 0.916133404 0.094176406 0.044060334 1.340370569 0.013785011 0.039058606 8.50E-06 5.070488678 0.722874582 K(ac)SAPSTGGVK(ac)KPHR ddPTM_HeLa_Curcumin_4h_R1 2 KSAPSTGGVKKPHR 14 3 K7EMV3;K7EP01;A0A590UJJ6;B4DEB1;K7EK07;K7ES00;P84243 K7EMV3 H3F3B;H3F3A Histone H3;Histone H3.3 0 2 ; K(1)SAPSTGGVK(0.5)K(0.5)PHR;K(1)SAPSTGGVK(0.5)K(0.5)PHR 70.68 0.0055145 19351600 7801.6 6829.9 7344.2 7424.9 7634.8 14566.7 9734.2 2831.6 9531.8 8237 FALSE TRUE FALSE 7184.095128 7420.246123 7616.382513 7394.177731 7543.759996 11545.40222 10007.31545 3694.941805 8486.185387 8523.235137 0.842883601 0.870590334 0.893602299 0.867531825 0.885081765 1.354579808 1.174121715 0.433514006 0.995653088 1 13.05718542 K(ac)SSLVTSKLAGGQVE ddPTM_HeLa_Curcumin_4h_R1 1 KSSLVTSKLAGGQVE 15 2 O43768;O43768-3;A0A1W2PRU0;O43768-5;O43768-7 O43768 ENSA Alpha-endosulfine 0 1 K(0.967)SSLVTSK(0.033)LAGGQVE 84.289 0.0036683 0 453.69 396.28 376.92 360.67 268.53 696.61 384.53 390.85 513.29 430.15 FALSE TRUE FALSE 417.7799578 430.5326774 390.8889868 359.1776431 265.3279551 552.1252336 395.3188769 510.0183657 456.9833712 445.0976805 0.938625331 0.967276839 0.878209445 0.806963637 0.596111745 1.240458573 0.888162069 1.145857164 1.026703556 1 8.797978172 -1.635534748 1.207576306 0.938507601 143.2026733 0.140140502 0.156872609 1927.7668 5.020032156 0.022436295 757786.4262 0.02314543 1.635534748 142.2641657 K(ac)STGGK(ac)APR ddPTM_HeLa_Curcumin_4h_R1 1 KSTGGKAPR 9 2 K7EMV3;K7EP01;A0A590UJJ6;B4DEB1;K7EK07;K7ES00;P84243;Q6NXT2;Q5TEC6;Q71DI3;P68431;Q16695 K7EMV3;Q5TEC6 H3F3B;H3F3A;H3F3C;HIST2H3PS2;HIST2H3A;HIST1H3A;HIST3H3 Histone H3;Histone H3.3;Histone H3.3C;Histone H3.2;Histone H3.1;Histone H3.1t 0 2 K(1)STGGK(1)APR 139.43 3.84E-05 50136000 3784.5 1430.7 2741.3 3606.1 2656.4 8351.7 4921.6 1831.1 3411 2725.1 FALSE TRUE FALSE 3484.952832 1554.363333 2842.894989 3591.178914 2624.724165 6619.463277 5059.68685 2389.393961 3036.821834 2819.797022 1.235887833 0.551232348 1.008191358 1.273559368 0.930820249 2.347496371 1.794344348 0.847363814 1.076964693 1 11.4613756 -5.309054852 24.99978389 1.064814828 1.676197648 0.365570228 0.389060852 314.1708414 164950.1705 0.053729545 0.120143192 4.91E-06 5.309054852 0.61138282 K(ac)TEK(ac)GNSAESR ddPTM_HeLa_Curcumin_4h_R1 1 KTEKGNSAESR 11 2 E7ENW1;C9J598;Q8N5S3-2;Q8N5S3 E7ENW1 C2orf73 Uncharacterized protein C2orf73 0 2 K(1)TEK(1)GNSAESR 61.419 0.018068 1067700 844.22 519.99 588.65 653.92 511.1 666.05 468.04 645.05 1202.3 860.13 FALSE TRUE FALSE 777.3990962 564.9356186 610.4658868 651.2142523 505.0054663 527.9037221 481.1719427 841.7227756 1070.410698 890.0194535 0.873463039 0.634745248 0.685901734 0.731685414 0.56740947 0.593137285 0.540630815 0.945735256 1.202682361 1 9.79769306 -7.507165319 1.256631826 0.963092038 0.656142895 0.576753206 0.135360256 0.198080857 0.625163323 0.023072532 0.024560626 3.11E-08 7.507165319 -0.306949143 K(ac)TNK(ac)NK(ac)SSISR ddPTM_HeLa_Curcumin_4h_R1 2 KTNKNKSSISR 11 3 Q92793;Q92793-2 Q92793 CREBBP CREB-binding protein 0 3 ; K(1)TNK(1)NK(1)SSISR;K(1)TNK(1)NK(1)SSISR 202.18 1.67E-29 11067500 1781.54 1510.08 1753.06 1515.23 1614.14 1961.67 1675.98 1364.66 1848.03 1418.55 FALSE TRUE FALSE 1640.529229 1640.604586 1818.029946 1508.96038 1594.892435 1554.797529 1723.003488 1780.738552 1645.305733 1467.844507 1.117645106 1.117696444 1.238571209 1.028011055 1.086554078 1.059238579 1.173832433 1.213165661 1.120899199 1 10.51948343 -9.022287278 0.627206331 0.989955747 1.128979986 0.021313697 0.072105357 0.80075627 0.527021896 0.060141197 0.014555055 9.50E-10 9.022287278 0.139024239 K(ac)TSK(ac)NK(ac)SSLSR ddPTM_HeLa_Curcumin_4h_R1 1 KTSKNKSSLSR 11 3 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 0 3 K(1)TSK(1)NK(1)SSLSR 116.51 0.012291 6465900 710.51 808.73 937.91 891.32 969.03 1010.8 845.36 549.54 1076.9 934.87 FALSE TRUE FALSE 654.2723838 878.6330176 972.6697697 887.631954 957.4749501 801.1486859 869.0785264 717.0922162 958.7667643 967.3566629 0.676350729 0.908282386 1.005492397 0.91758499 0.98978483 0.828183354 0.898405479 0.741290409 0.991120236 1 9.917904097 -9.802384254 1.819869285 1.000379317 0.842202261 0.156330731 0.099797087 0.486967844 2.920739433 0.089531655 0.018680091 1.58E-10 9.802384254 -0.158177056 K(ac)YAEAVTR ddPTM_HeLa_Curcumin_4h_R1 2 KYAEAVTR 8 1 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 1 ; K(1)YAEAVTR;K(1)YAEAVTR 81.338 0.013693 4358000 3230.2 3285 3283.2 2712.3 5020.2 6147.6 4709.2 4726.4 5319.6 3345.2 FALSE TRUE FALSE 2974.526262 3568.940762 3404.87828 2701.077221 4960.337394 4872.518462 4841.327478 6167.457602 4736.053189 3461.445451 0.859330677 1.031055035 0.983657934 0.780332165 1.433024863 1.407654268 1.398643297 1.781757849 1.368229907 1 11.7571589 -5.694684956 6.347640848 0.935008967 1.497546805 0.633018177 0.182839867 0.060231664 4.383482233 0.017526105 0.03514935 2.02E-06 5.694684956 0.562537838 K(ac)YDEELEER ddPTM_HeLa_Curcumin_4h_R1 1 KYDEELEER 9 1 Q01995;E9PJ32 Q01995 TAGLN Transgelin 0 1 K(1)YDEELEER 82.029 0.012921 7158000 2131.7 2509.5 2072.8 1844.9 3925 5126.9 3359 3312.1 4404.9 1979.2 FALSE TRUE FALSE 1962.973696 2726.409998 2149.619791 1837.266293 3878.196939 4063.523148 3453.2445 4321.944043 3921.693491 2047.977053 0.95849399 1.331269798 1.0496308 0.897112734 1.893672067 1.984164394 1.686173434 2.110347886 1.914910856 1 10.99998383 -5.756540308 24.99883121 1.009746492 1.906672429 0.507545046 0.321865864 26.04687156 132909.5403 0.020930911 0.040826168 1.75E-06 5.756540308 0.896925937 K(ac)YELGRPAANTK ddPTM_HeLa_Curcumin_4h_R1 1 KYELGRPAANTK 12 2 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 1 K(1)YELGRPAANTK 70.563 0.01787 9755600 3842.7 4723.9 3432.3 3296.9 6930.4 9202.6 6044.5 6524.5 9572.7 3377.4 FALSE TRUE FALSE 3538.54624 5132.212867 3559.504057 3283.258301 6847.759506 7293.877025 6214.092402 8513.790015 8522.59876 3494.764399 1.012527838 1.468543307 1.018524756 0.939479154 1.959433806 2.087086909 1.778114829 2.436155644 2.438676199 1 11.77097948 -5.730003349 6.443970257 1.041191252 2.053789933 0.278202372 0.487724319 0.047363298 5.897908677 0.028795445 0.057066631 1.86E-06 5.730003349 1.012598681 K(ac)YVIYIER ddPTM_HeLa_Curcumin_4h_R1 2 KYVIYIER 8 1 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;Q9UNX3;P61254;J3QRC4;J3KS10 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 0 1 ; K(1)YVIYIER;K(1)YVIYIER 102.61 0.0037178 23280000 4889.6 3721.2 4185.6 4062.4 4340.2 4947.2 4251 4638.8 4201.9 3978 FALSE TRUE FALSE 4502.583001 4042.843947 4340.722018 4045.590865 4288.44595 3921.094954 4370.271619 6053.148766 3740.962083 4116.235204 1.093859504 0.982170296 1.054536926 0.982837633 1.041836955 0.952592541 1.061715719 1.470554637 0.908830982 1 12.00710971 -4.264739594 4.809481506 1.03125635 1.49380037 0.856554072 0.056151497 0.03978482 2.635379535 0.006449344 0.061160695 5.44E-05 4.264739594 0.46254402 KAAAGPLDMSLPS(ph)TPDIK ddPTM_HeLa_Curcumin_4h_R1 1 KAAAGPLDMSLPSTPDIK 18 1 K7ELQ4;P17544-4;P17544-2;P17544 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 0 KAAAGPLDMS(0.001)LPS(0.5)T(0.5)PDIK 74.993 0.0046667 22077000 4551.8 3510.5 3800.8 3494.6 3307.8 3908.6 3405.3 4121.9 4432.5 3768.5 TRUE FALSE FALSE 4191.520227 3813.931978 3941.660992 3480.140271 3268.356645 3097.912301 3500.843553 5378.648335 3946.26584 3899.455094 1.07489896 0.978067931 1.010823537 0.892468354 0.838157272 0.794447487 0.89777763 1.379333318 1.012004432 1 11.92905682 -6.683488287 2.177049625 1.033864089 0.942956645 0.01743704 0.153311173 0.68844239 6.675458391 0.025045352 0.036716254 2.07E-07 6.683488287 -0.090907444 KAAAGPLDMSLPST(ph)PDIK ddPTM_HeLa_Curcumin_4h_R1 1 KAAAGPLDMSLPSTPDIK 18 1 K7ELQ4;P17544-4;P17544-2;P17544 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 0 KAAAGPLDMSLPS(0.208)T(0.792)PDIK 105.67 0.00052059 20443000 7749.5 5483.4 5874.6 5878.2 5975.2 7032.6 5564.7 6754.4 6825.7 5547.8 TRUE FALSE FALSE 7136.118898 5957.360662 6092.317844 5853.877566 5903.949643 5573.959486 5720.830505 8813.785467 6076.937787 5740.585637 1.243099459 1.037761831 1.061271137 1.019735256 1.028457725 0.970974015 0.996558691 1.535346047 1.058591958 1 12.48698221 -9.873113197 0.007904111 4.27E-06 2.156449061 0.051203826 0.158795345 33613.16796 51.77094862 7388.746468 6745.604383 1.34E-10 9.873113197 2.156444791 KAALLAQYADVT(ph)DEEDEADEKDDSGATTMNIGSDK ddPTM_HeLa_Curcumin_4h_R1 2 KAALLAQYADVTDEEDEADEKDDSGATTMNIGSDK 35 2 Q96MW1 Q96MW1 CCDC43 Coiled-coil domain-containing protein 43 1 0 KAALLAQYADVT(0.999)DEEDEADEKDDS(0.001)GATTMNIGSDK;KAALLAQYADVT(1)DEEDEADEKDDSGATTMNIGSDK ; 113.37 3.45E-15 362470000 8539.8 6745 7074.1 7930.7 7163.4 8744.6 7995.6 7614 8660.7 6350.1 TRUE FALSE FALSE 7863.865819 7328.007745 7336.272369 7897.884865 7077.981134 6930.871388 8219.935017 9935.473549 7710.642878 6570.765502 1.196795992 1.115244144 1.116501931 1.201973326 1.077192776 1.054804252 1.250985903 1.512072459 1.173477105 1 12.68184574 -4.37180424 2.567774821 1.102853712 1.550389267 0.785400957 0.062490142 0.157714842 1.527253592 0.011263138 0.135292354 4.25E-05 4.37180424 0.447535555 KAALLAQYADVTDEEDEADEKDDS(ph)GATTMNIGSDK ddPTM_HeLa_Curcumin_4h_R1 1 KAALLAQYADVTDEEDEADEKDDSGATTMNIGSDK 35 2 Q96MW1 Q96MW1 CCDC43 Coiled-coil domain-containing protein 43 1 0 KAALLAQYADVT(0.153)DEEDEADEKDDS(0.257)GAT(0.257)T(0.257)MNIGS(0.075)DK 44.178 0.007261 70565000 3688.3 2971.1 2931.8 3334.8 3375 3548.5 3323.6 3653.5 3757.1 3445.6 TRUE FALSE FALSE 3396.367163 3227.908645 3040.455087 3321.001481 3334.755329 2812.5011 3416.851271 4767.435331 3344.95553 3565.334344 0.952608321 0.905359311 0.852782599 0.93146986 0.93532752 0.788846383 0.958353675 1.337163607 0.938188458 1 11.79982166 -4.263499356 6.306585924 0.944301189 1.345664016 0.801987248 0.06126976 0.046645314 10.27875786 0.009794602 0.08020198 5.45E-05 4.263499356 0.401362827 KAAPAPGK(ac)VGDVTPQVK ddPTM_HeLa_Curcumin_4h_R1 1 KAAPAPGKVGDVTPQVK 17 2 E7ETY2;Q13428-6;Q13428-7;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4 E7ETY2;Q13428 TCOF1 Treacle protein 0 1 K(0.001)AAPAPGK(0.999)VGDVTPQVK 120.24 7.06E-05 5226300 5860.8 4999.7 5083 5584 4463.4 6864.7 5590.5 6910.8 6760.4 5350.3 FALSE TRUE FALSE 5396.911496 5431.85179 5271.380451 5560.894888 4410.17687 5440.883839 5747.354384 9017.871107 6018.801034 5536.222527 0.974836447 0.981147662 0.952161953 1.004456533 0.796603975 0.982779108 1.038136447 1.62888523 1.087167469 1 12.43468622 -4.255186543 3.563324038 0.972638722 1.71016668 0.891733034 0.068199764 0.056712663 1.258104112 0.008028841 0.112379623 5.56E-05 4.255186543 0.737527958 KAAS(ph)PSPQS(ph)VR ddPTM_HeLa_Curcumin_4h_R1 2 KAASPSPQSVR 11 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 0 KAAS(0.938)PS(0.062)PQS(1)VR;KAAS(0.981)PS(0.02)PQS(1)VR ; 138.31 0.0024573 144544500 13034.9 11502.2 10378.7 11566.5 11756.9 14796.9 12205.7 11913.5 13919.9 11710.2 TRUE FALSE FALSE 12003.17391 12496.39892 10763.34375 11518.64089 11616.70665 11727.85614 12548.15909 15545.87131 12392.9218 12117.12858 0.990595572 1.031300348 0.888275113 0.950608126 0.958701277 0.967874201 1.035572001 1.282966604 1.022760608 1 13.56476024 -4.26479469 2.939582305 0.983176927 1.332673535 0.846309034 0.038992377 0.109341827 1.351917171 0.005418039 0.089560575 5.44E-05 4.26479469 0.349496608 KAAVLS(ph)DS(ph)EDEEK ddPTM_HeLa_Curcumin_4h_R1 1 KAAVLSDSEDEEK 13 1 Q96ST2-3;Q96ST2;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 2 0 KAAVLS(1)DS(1)EDEEK 93.228 0.016136 7426900 5142.7 5233.8 5827.5 4787.6 5517.5 5559.7 5319 5037.9 4787.1 4631.4 TRUE FALSE FALSE 4735.649868 5686.186351 6043.472276 4767.79018 5451.707416 4406.555549 5468.236825 6573.932518 4261.967107 4792.340805 0.988170512 1.186515438 1.261068969 0.994877112 1.137587588 0.91949962 1.141036718 1.371758142 0.889328885 1 12.22651479 -4.356306813 3.213247293 1.033148329 1.389435963 0.426279671 0.112266118 0.188166132 3.085926075 0.015153883 0.143787979 4.40E-05 4.356306813 0.356287633 KAAVLS(ph)DS(ph)EDEEKASAK ddPTM_HeLa_Curcumin_4h_R1 1 KAAVLSDSEDEEKASAK 17 2 Q96ST2-3;Q96ST2;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 2 0 KAAVLS(0.999)DS(0.955)EDEEKAS(0.045)AK 65.467 0.018485 115860000 4655.8 3864.4 4328.3 4759.9 3820.5 4131.8 4083.7 3930.7 4321.7 3817.4 TRUE FALSE FALSE 4287.288517 4198.421517 4488.710606 4740.204795 3774.943033 3274.818105 4198.277631 5129.152335 3847.620322 3950.054366 1.085374559 1.062876894 1.136366791 1.20003533 0.955668627 0.829056464 1.062840468 1.298501707 0.974067688 1 11.94765679 -9.278128758 0.99030632 0.999745097 1.07186662 0.078933601 0.120706588 1.682444646 2.940453382 0.085667266 0.022839686 5.27E-10 9.278128758 0.072121523 KADIDLTK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 KADIDLTKR 9 2 P62269 P62269 RPS18 40S ribosomal protein S18 0 1 KADIDLTK(1)R 70.942 0.017617 3121700 1023.6 1274.1 1000.7 999.4 1710.5 2085.8 1799.3 1814.3 1835.1 1154.8 FALSE TRUE FALSE 942.5809799 1384.227527 1037.786822 995.2647476 1690.103405 1653.181568 1849.783515 2367.471718 1633.794121 1194.929214 0.78881742 1.158418014 0.868492301 0.832906867 1.414396254 1.38349749 1.548027694 1.981265242 1.367272724 1 10.22270944 -4.630567259 0.684448807 0.903962944 2.282521297 0.673216477 0.204743186 0.556667329 0.241331149 0.026315549 0.537103646 2.34E-05 4.630567259 1.378558354 KADTTTPTPTAILAPGS(ph)PAS(ph)PPGSLEPK ddPTM_HeLa_Curcumin_4h_R1 2 KADTTTPTPTAILAPGSPASPPGSLEPK 28 1 P25440-2;P25440;A0A0G2JK44;A0A140T9E9;H0Y6K2;P25440-3;P25440-4;A0A0G2JHL0;A0A140T9V2;A0A140T9F7;U3KQA6;E9PIQ3;H0YDJ7;U3KPW0 P25440-2 BRD2 Bromodomain-containing protein 2 2 0 KADTTTPTPTAILAPGS(0.998)PAS(0.999)PPGS(0.003)LEPK;KADTTTPTPTAILAPGS(0.999)PAS(0.998)PPGS(0.003)LEPK ; 125.99 1.09E-10 95856000 4640.9 3295.7 4035 4061.6 3899.2 4858.8 3587.4 2937.8 4599.7 4143.4 TRUE FALSE FALSE 4273.567868 3580.565623 4184.54065 4044.794175 3852.704587 3851.03011 3688.052789 3833.521696 4095.124418 4287.382842 0.996777761 0.835140167 0.976012827 0.943418007 0.898614546 0.898223987 0.860210745 0.89414028 0.95515716 1 12.06588153 -6.843608555 0.485929528 1.007396529 0.877688448 0.315405021 0.044756297 0.514408601 0.272510487 0.014952463 0.0254775 1.43E-07 6.843608555 -0.129708081 KADTTTPTPTAILAPGSPAS(ph)PPGSLEPK ddPTM_HeLa_Curcumin_4h_R1 1 KADTTTPTPTAILAPGSPASPPGSLEPK 28 1 P25440-2;P25440;A0A0G2JK44;A0A140T9E9;H0Y6K2;P25440-3;P25440-4;A0A0G2JHL0;A0A140T9V2;A0A140T9F7;U3KQA6;E9PIQ3;H0YDJ7;U3KPW0 P25440-2 BRD2 Bromodomain-containing protein 2 1 0 KADTTTPTPTAILAPGS(0.288)PAS(0.71)PPGS(0.002)LEPK 120.27 8.48E-11 51216000 1311.2 1220.9 1413.8 1232 1309.6 1408 1283.5 1277 1322.9 1454 TRUE FALSE FALSE 1207.417136 1326.429156 1466.196672 1226.90231 1293.983875 1115.964929 1319.511556 1666.351421 1177.78118 1504.526392 0.802523068 0.881625715 0.97452373 0.815474103 0.860060603 0.741738353 0.877027856 1.107558784 0.782825204 1 10.5550937 -9.537561712 1.299446786 1.000004692 0.868592562 0 0.116775273 0.578204555 1.748510734 0.066750103 0.015897075 2.90E-10 9.537561712 -0.13141213 KADVSEQVSNGPVESVTLENS(ph)PLVWK ddPTM_HeLa_Curcumin_4h_R1 1 KADVSEQVSNGPVESVTLENSPLVWK 26 1 F5GYK2;Q9NRL3-2;Q9NRL3;Q9NRL3-3;M0R2A7;M0QYS2;M0R0P4;M0QXN2;M0R0W8 F5GYK2 STRN4 Striatin-4 1 0 KADVSEQVSNGPVES(0.022)VT(0.259)LENS(0.719)PLVWK 98.887 2.06E-06 34636000 769.83 571.23 818.35 594.39 1004.6 1173.4 858.72 585.04 995.3 586.08 TRUE FALSE FALSE 708.8971432 620.6045758 848.6787709 591.9305717 992.6208011 930.0236131 882.8133721 763.4160028 886.1180801 606.4462364 1.168936504 1.023346405 1.399429529 0.976064383 1.636782853 1.533563171 1.455715806 1.25883542 1.461165107 1 9.244235941 -5.765245769 24.9999997 1.097086534 1.474569348 0.352254927 0.183119355 48.48511558 318448.2985 0.021226769 0.039559205 1.72E-06 5.765245769 0.377482815 KAEAAAAPTVAPGPAQPGHVS(ph)PTPATTSPGEK ddPTM_HeLa_Curcumin_4h_R1 1 KAEAAAAPTVAPGPAQPGHVSPTPATTSPGEK 32 1 A0A0C4DGH3;Q9Y6R0;M0QYC2 A0A0C4DGH3 NUMBL Numb-like protein 1 0 KAEAAAAPTVAPGPAQPGHVS(0.544)PT(0.201)PAT(0.19)T(0.06)S(0.005)PGEK 78.642 1.36E-06 6323500 2567.1 1914 2991.2 2279.1 2411.4 2442.6 1697.7 2031.9 2386.7 2307.1 TRUE FALSE FALSE 2363.911326 2079.437631 3102.056503 2269.669688 2382.64563 1935.977226 1745.332893 2651.416956 2124.884981 2387.271553 0.990214675 0.871051988 1.299415016 0.950737961 0.998062255 0.81095811 0.731099439 1.110647405 0.890089348 1 11.22114697 -5.308746452 9.826603478 1.005871364 0.868982033 0.118605007 0.14209489 0.704705349 144.065781 0.018122168 0.040635751 4.91E-06 5.308746452 -0.136889332 KAEAAASALADADADLEER ddPTM_HeLa_Curcumin_4h_R1 1 KAEAAASALADADADLEER 19 1 M0R1T5;O43633 M0R1T5 CHMP2A Charged multivesicular body protein 2a 0 0 88.471 0.0034892 4381900 2623.7 2613.3 2487.4 2405.6 2464.6 2735.9 2612.5 2368 2904.2 3192 FALSE FALSE TRUE 2416.031376 2839.182007 2579.585232 2395.646265 2435.211255 2168.4435 2685.799719 3089.992299 2585.616526 3302.921762 0.731483078 0.859597112 0.78100101 0.725311236 0.737290021 0.656522817 0.813158746 0.935532998 0.782827058 1 11.68952708 -9.359007591 0.823448953 1.017196584 0.772326115 0 0.099457977 0.448771378 0.481351619 0.073913995 0.014644438 4.38E-10 9.359007591 -0.24487047 KAEAAVVAVAEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 KAEAAVVAVAEKR 13 2 A0A087WYP2;Q8IZQ5 A0A087WYP2 C11orf31;SELH Selenoprotein H 0 1 ; KAEAAVVAVAEK(1)R;KAEAAVVAVAEK(1)R 141.34 0.00011344 50217000 16963.1 13393.8 13686.9 14169.7 14057 20219.5 16576.3 20230.2 17074.3 14999.2 FALSE TRUE FALSE 15620.45274 14551.50039 14194.14855 14111.06954 13889.37946 16025.74778 17041.38637 26398.29485 15201.29201 15520.42108 1.006445164 0.937571237 0.914546614 0.90919373 0.894909963 1.032558826 1.097997681 1.700874912 0.979438117 1 13.92188008 -4.190177712 2.225618986 0.978889109 1.976615803 0.957284514 0.046693476 0.136190304 0.651605643 0.007815132 0.284982259 6.45E-05 4.190177712 0.997726694 SETSWES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SETSWESPK 9 0 E5RJU9;Q86UE4 E5RJU9 MTDH Protein LYRIC 1 0 SETSWES(1)PK;SETSWES(1)PK ; 136.96 0.0028254 65773000 6831.8 6433.4 7166.2 8912.3 6969.6 7700.7 4953.1 2201.3 10386.5 7515.6 TRUE FALSE FALSE 6291.055821 6989.474429 7431.785676 8875.423264 6886.492072 6103.488015 5092.070655 2872.466236 9247.126936 7776.766541 0.808955211 0.898763566 0.95563955 1.141274232 0.885521256 0.784836215 0.654779931 0.369365111 1.189070919 1 12.92495471 -4.438431106 1.326155981 0.9260957 0.242690631 0.721997904 0.118910503 0.37122402 0.708153731 0.015362886 0.311085595 3.64E-05 4.438431106 -0.683405068 down KAEAGAGSATEFQFR ddPTM_HeLa_Curcumin_4h_R1 2 KAEAGAGSATEFQFR 15 1 P46783;Q9NQ39 P46783 RPS10;RPS10P5 40S ribosomal protein S10;Putative 40S ribosomal protein S10-like 0 0 ; ; 156.72 0.00030217 12745800 5282.1 3999.4 4407.7 4884.5 4743.2 5531.1 4138.8 4437.1 5369.5 4439.8 FALSE FALSE TRUE 4864.016211 4345.090315 4571.053239 4864.289233 4686.640438 4383.887512 4254.923589 5789.951364 4780.479284 4594.08272 1.058756777 0.945801497 0.994987143 1.058816206 1.02014716 0.954246534 0.926174788 1.260306293 1.040573184 1 12.16556112 -4.248846678 24.95085494 1.012202342 1.260306452 0.741272967 0.045631291 861.7796053 1707477.451 0.006748663 0.162629609 5.64E-05 4.248846678 0.24810411 KAEALHNIWLGR ddPTM_HeLa_Curcumin_4h_R1 1 KAEALHNIWLGR 12 1 C9K0L6;Q9BPX7;Q9BPX7-2 C9K0L6 C7orf25 UPF0415 protein C7orf25 0 0 79.23 0.01359 9015800 5927.1 5556.5 3467.7 3851.3 5646.9 15949 5957.9 5442.7 8238.2 4252 FALSE FALSE TRUE 5457.963781 6036.779101 3596.216012 3835.364341 5579.564406 12640.99762 6125.062639 7102.154175 7334.490071 4399.756684 1.240514913 1.372071125 0.817367021 0.871721919 1.268152947 2.873112885 1.392136675 1.614215214 1.667021747 1 12.10320803 -5.499135135 24.74813693 1.096841195 1.930983181 0.40865169 0.428715303 409.0939474 426401.1789 0.052774744 0.117332227 3.17E-06 5.499135135 0.834141986 KAEDS(ph)DS(ph)EPEPEDNVR ddPTM_HeLa_Curcumin_4h_R1 2 KAEDSDSEPEPEDNVR 16 1 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 2 0 KAEDS(1)DS(1)EPEPEDNVR;KAEDS(1)DS(1)EPEPEDNVR ; 109.14 0.0025976 594130000 9408.4 7513.9 7524.6 8224.2 8271.6 9185.8 7399.5 6401.9 9545.4 8028.3 TRUE FALSE FALSE 8663.715212 8163.368035 7803.468295 8190.17044 8172.966572 7280.561535 7607.110055 8353.809839 8498.293501 8307.282827 1.042906013 0.982676069 0.939352669 0.985902444 0.983831506 0.876407086 0.91571579 1.00560075 1.022993159 1 13.02016096 -7.003875299 4.192918079 1.020162502 0.949509387 0.431576915 0.036341683 0.151957485 6.358058461 0.00637967 0.008195915 9.91E-08 7.003875299 -0.070653115 KAEDS(ph)DSEPEPEDNVR ddPTM_HeLa_Curcumin_4h_R1 2 KAEDSDSEPEPEDNVR 16 1 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 0 KAEDS(1)DSEPEPEDNVR;KAEDS(0.984)DS(0.016)EPEPEDNVR ; 197.94 5.22E-08 167694000 6749.6 5495.4 6056.1 6814.1 6456.7 7486.7 5259.9 6286.8 7439.8 5800.8 TRUE FALSE FALSE 6215.362038 5970.397889 6280.544393 6785.90506 6379.70807 5933.874028 5407.478638 8203.616379 6623.672553 6002.377368 1.035483385 0.994672198 1.046342809 1.130536226 1.062863542 0.988587299 0.900889482 1.366727861 1.103508185 1 12.55131831 -4.24884571 24.86636036 1.020556295 1.366728095 0.727823136 0.061716278 675.3437706 1333450.309 0.007794904 0.185302597 5.64E-05 4.24884571 0.346171799 KAEEAGGTRLEPLK(ac)PLK ddPTM_HeLa_Curcumin_4h_R1 1 KAEEAGGTRLEPLKPLK 17 3 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 0 1 K(0.005)AEEAGGTRLEPLK(0.995)PLK 55.815 0.018445 17564000 6735.6 4464.4 5118.7 5914.4 4489.1 5840.9 5626.9 1807.5 6785.5 6022.5 FALSE TRUE FALSE 6202.470153 4850.282843 5308.403525 5889.92778 4435.570414 4629.431499 5784.77567 2358.598429 6041.147626 6231.781427 0.995296486 0.778314018 0.851827617 0.945143511 0.711766044 0.742874498 0.928269988 0.378479004 0.969409421 1 12.60542892 -3.429544476 0.280596621 1.016144313 5.41E-16 0.52650745 0.124462344 7.194356544 0.294384686 0.057010883 2.735846034 0.000371925 3.429544476 -1.016144313 KAEEDAALQAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 KAEEDAALQAKK 12 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;A0A2R8Y4M7;H0YA99;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 0 1 ; KAEEDAALQAK(1)K;KAEEDAALQAK(1)K 161.87 1.96E-06 18344600 16532.4 13040.5 13493.3 13926.3 15316.3 19657.8 17391.2 16881.3 16785.7 14254.4 FALSE TRUE FALSE 15223.8431 14167.66271 13993.37357 13868.67666 15133.66313 15580.55069 17879.15027 22028.33066 14944.35071 14749.73934 1.032143196 0.96053648 0.948720058 0.940265881 1.026029191 1.056327189 1.212167202 1.493472539 1.013194224 1 13.84840184 -4.288426952 1.41551551 1.000740806 1.682705065 0.961783144 0.031199921 0.183470982 0.335093087 0.005465169 0.174356407 5.15E-05 4.288426952 0.681964259 TKEGVMYVGAK(ac)TK ddPTM_HeLa_Curcumin_4h_R1 1 TKEGVMYVGAKTK 13 2 F8W754;O76070 F8W754 SNCG Gamma-synuclein 0 1 TKEGVMYVGAK(1)TK 90.707 0.0041342 3572400 1871.8 1478 1654.2 1387 1587.9 2325.6 2115 3044 2271.9 1690.7 FALSE TRUE FALSE 1723.645055 1605.751734 1715.506107 1381.260962 1568.96533 1843.244345 2174.341208 3972.101587 2022.678254 1749.451699 0.985248724 0.917859999 0.980596439 0.789539352 0.896832608 1.053612595 1.2428701 2.270483712 1.156178393 1 10.77268712 -4.172891536 1.938377805 0.966531528 2.87918021 0.948756319 0.090418486 0.127472226 0.411842942 0.010600266 0.46873182 6.72E-05 4.172891536 1.912648682 up GPSPAPAS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 GPSPAPASSPK 11 0 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 1 0 GPSPAPAS(0.847)S(0.153)PK 116.84 0.0046111 36205000 5234.8 4224.6 4792 5581.5 5953.8 6496.4 5267.4 10058 4886.9 4627 TRUE FALSE FALSE 4820.460056 4589.7556 4969.595735 5558.405232 5882.804824 5148.97341 5415.189068 13124.6379 4350.819296 4787.787906 1.00682406 0.958638037 1.037973242 1.160954775 1.228710406 1.075438911 1.131041971 2.741273874 0.908732672 1 12.22514353 -4.25944613 4.567193349 1.035509995 2.853063769 0.970134326 0.088770989 0.022932619 1.236038481 0.012741916 0.133448447 5.50E-05 4.25944613 1.817553774 up KAEGAATEEEGTPK ddPTM_HeLa_Curcumin_4h_R1 2 KAEGAATEEEGTPK 14 1 P80723;P80723-2;U3KQP0 P80723 BASP1 Brain acid soluble protein 1 0 0 ; ; 173.71 6.06E-06 4836700 5232.6 4447 4434.8 6349.8 6277.2 8228.3 6188.9 6000.3 6829.7 5389 FALSE FALSE TRUE 4818.434189 4831.378865 4599.157589 6323.52621 6202.34849 6521.657828 6362.543877 7829.763848 6080.498997 5576.267349 0.864096695 0.866418083 0.824773509 1.134007 1.112276027 1.169538227 1.141004095 1.404122751 1.090424583 1 12.44508402 -5.422027958 0.897477745 0.922973948 1.29927623 0.630911387 0.101821058 0.318328884 0.433963449 0.016149816 0.079062561 3.78E-06 5.422027958 0.376302282 KAEGEPQEES(ph)PLK ddPTM_HeLa_Curcumin_4h_R1 4 KAEGEPQEESPLK 13 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK;KAEGEPQEES(1)PLK ;;; 159.14 0.00046237 1116902000 32611.6 27935.1 32168.9 30991.2 34648.1 33980.1 32804.6 29445.3 27647.7 25687.3 TRUE FALSE FALSE 30030.35745 30349.68557 33361.10773 30862.96663 34234.94404 26932.24423 33725.00879 38423.03642 24614.81648 26579.93176 1.129813188 1.141827069 1.255123904 1.161137918 1.287999696 1.013254829 1.268814724 1.445565653 0.926067708 1 14.69804978 -1.000000027 0.068834207 0.749591443 2.17838893 0.568331391 0.097856518 142.8884484 0.734607531 2.770801069 19.95936608 0.099999994 1.000000027 1.428797487 KAEGEPQEES(ph)PLKSK ddPTM_HeLa_Curcumin_4h_R1 2 KAEGEPQEESPLKSK 15 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 KAEGEPQEES(1)PLKSK;KAEGEPQEES(0.868)PLKS(0.132)K ; 102.59 0.0022194 3426830000 10792.3 9077 9474.7 9254.5 9454.5 11460.4 10410 9943.7 11524.6 10089.5 TRUE FALSE FALSE 9938.078067 9861.575434 9825.840717 9216.207331 9341.761262 9083.383855 10702.07658 12975.48835 10260.38021 10440.10937 0.951913214 0.944585452 0.941162622 0.882769232 0.894795344 0.87004681 1.025092382 1.242849849 0.982784743 1 13.34984921 -4.315897844 3.326081341 0.953387195 1.265681959 0.813816376 0.043892582 0.105382936 1.911365785 0.007322948 0.07681241 4.83E-05 4.315897844 0.312294764 KAEGEPQEESPLKS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 KAEGEPQEESPLKSK 15 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 KAEGEPQEES(0.235)PLKS(0.765)K 51.009 0.018086 627760000 7182 5527.9 5576 6275.5 5835.3 7824.7 6410.5 6722.8 7464.3 6929.7 TRUE FALSE FALSE 6613.537122 6005.707044 5782.651465 6249.533644 5765.717859 6201.769017 6590.361377 8772.550772 6645.484965 7170.506559 0.922324952 0.837556872 0.806449505 0.871560969 0.804087941 0.864899706 0.919092859 1.223421344 0.926780404 1 12.80785933 -4.261490958 10.24010366 0.918267616 1.224062084 0.679829326 0.066221827 0.043723242 169.8731965 0.011947799 0.092414856 5.48E-05 4.261490958 0.305794467 KAEK(ac)AAAEEPR ddPTM_HeLa_Curcumin_4h_R1 2 KAEKAAAEEPR 11 2 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 0 1 ; K(0.062)AEK(0.938)AAAEEPR;K(0.019)AEK(0.981)AAAEEPR 115.14 0.00065368 7188200 16114.4 13769.6 15971.1 15017.5 13251.5 15658.3 10926.3 11530.3 16333.7 13751.9 FALSE TRUE FALSE 14838.92824 14959.78287 16563.00302 14955.36156 13093.48452 12410.59207 11232.86257 15045.83539 14541.93397 14229.7775 1.04280817 1.05130125 1.163967814 1.050990542 0.92014682 0.872156439 0.789391301 1.057348605 1.021936849 1 13.79662548 -5.695447667 4.996796187 1.037187606 0.895559801 0.462333218 0.075031551 0.146264199 7.022501005 0.010893361 0.021955832 2.02E-06 5.695447667 -0.141627805 KAEPSEVDMNS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 KAEPSEVDMNSPK 13 1 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 0 KAEPSEVDMNS(1)PK;KAEPSEVDMNS(1)PK;KAEPSEVDMNS(1)PK ;; 110.25 0.0050242 153606000 24575.3 21015 24401.1 26495.9 23321.6 30127.8 25839.7 8449.6 28657.1 21629 TRUE FALSE FALSE 22630.13907 22831.44296 25305.42623 26386.26699 23043.50515 23878.95467 26564.69244 11025.84414 25513.48783 22380.60614 1.011149516 1.020144084 1.130685473 1.178979105 1.02961935 1.066948523 1.186951429 0.492651721 1.139981986 1 14.44996149 -4.251938881 24.90813486 1.041117529 0.492651415 0.828222857 0.078675303 391.9096882 1027475.685 0.011045495 0.189459697 5.60E-05 4.251938881 -0.548466113 KAEQGS(ph)EEEGEGEEEEEEGGESK ddPTM_HeLa_Curcumin_4h_R1 5 KAEQGSEEEGEGEEEEEEGGESK 23 1 Q5STZ8;Q8NE71 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 0 KAEQGS(1)EEEGEGEEEEEEGGESK;KAEQGS(1)EEEGEGEEEEEEGGESK;KAEQGS(1)EEEGEGEEEEEEGGESK;KAEQGS(1)EEEGEGEEEEEEGGESK;KAEQGS(1)EEEGEGEEEEEEGGESK ;;;; 106.42 1.02E-05 887149000 27710.7 21037 25623.4 25765.9 29771.6 30268.2 26069.9 22802 23815.8 21596 TRUE FALSE FALSE 25517.36885 22855.34454 26573.02574 25659.28753 29416.59311 23990.23413 26801.35123 29754.22483 21203.26632 22346.45939 1.141897623 1.022772518 1.189138077 1.148248458 1.3163872 1.073558621 1.199355601 1.331496158 0.948842318 1 14.44775865 -1 0.023835775 1.11E-14 2.713499432 0.584152783 0.078453622 1085.662701 2.011492696 80.54898181 161.7614113 0.1 1 2.713499432 KAGNFYVPAEPK ddPTM_HeLa_Curcumin_4h_R1 2 KAGNFYVPAEPK 12 1 P18124;A8MUD9;C9JZ88;C9JIJ5 P18124 RPL7 60S ribosomal protein L7 0 0 ; ; 106.49 0.0013097 21541500 26545 19563.5 22728 22069 21955 26178 20648 21150 26111 23127 FALSE FALSE TRUE 24443.93524 21254.48177 23570.31967 21977.68433 21693.20096 20748.38771 21227.32731 27598.53764 23246.68863 23930.66153 1.021448371 0.88816942 0.984942253 0.918390171 0.906502352 0.867021068 0.887034706 1.153270987 0.971418554 1 14.54657266 -7.282372706 24.32951945 1.010128401 0.937687822 0.080486228 0.078609667 743.9127194 864601.3878 0.012534029 0.01434143 5.22E-08 7.282372706 -0.072440579 KAGTELVNFLS(ph)YFVELGT(ph)QPATQ ddPTM_HeLa_Curcumin_4h_R1 1 KAGTELVNFLSYFVELGTQPATQ 23 1 V9GYE3;V9GYM3;P02652 V9GYE3 APOA2 Apolipoprotein A-II;Proapolipoprotein A-II;Truncated apolipoprotein A-II 2 0 KAGT(0.01)ELVNFLS(0.516)Y(0.482)FVELGT(0.938)QPAT(0.053)Q 41.115 0.0096555 0 790.99 660.79 770.07 956.8 803.8 578.36 629.75 825.98 1038.5 835.24 TRUE FALSE FALSE 728.3823069 717.9057432 798.6094716 952.8410151 794.21521 458.4016165 647.4190901 1077.8175 924.5791482 864.2645278 0.842777047 0.830655106 0.92403361 1.102487704 0.918949216 0.530395037 0.749098302 1.24709214 1.069787222 1 9.755329139 -5.4844398 24.9817168 0.930352925 0.814849954 0.056097605 0.185376193 1149.089455 746799.6549 0.025484266 0.056972884 3.28E-06 5.4844398 -0.11550297 KAGTQIENIEEDFRDGLK ddPTM_HeLa_Curcumin_4h_R1 2 KAGTQIENIEEDFRDGLK 18 2 P12814-4;P12814-3;P12814;P12814-2;G3V2N5;G3V5M4;G3V380 P12814-4 ACTN1 Alpha-actinin-1 0 0 ; ; 72.662 0.0046243 27998000 3906.7 3404.2 3350.6 3783.9 3697.8 4919.6 3682.3 4035 4058.8 3605.8 FALSE FALSE TRUE 3597.480573 3698.443879 3474.776183 3768.243224 3653.70615 3899.219505 3785.615428 5265.252925 3613.559795 3731.101282 0.964187327 0.991247248 0.931300418 1.009954686 0.979256759 1.045058606 1.014610739 1.411179308 0.968496838 1 11.86538581 -4.23167925 3.270347983 0.98519278 1.486839474 0.950457926 0.028933057 0.058527108 0.93180387 0.004030725 0.076410288 5.87E-05 4.23167925 0.501646694 KAKDDATLSGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 KAKDDATLSGKR 12 3 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 0 1 ; KAKDDATLSGK(1)R;KAKDDATLSGK(1)R 74.698 0.012607 99611000 20753.5 17112.9 16713.4 14396.1 12339.1 25310 12412.6 19914.9 25726 23722.7 FALSE TRUE FALSE 19110.83858 18592.06282 17332.81331 14336.53275 12191.96429 20060.4207 12760.86415 25986.86133 22903.92216 24547.06206 0.778538732 0.757404808 0.706105409 0.584042714 0.496677128 0.817222878 0.519853012 1.058654648 0.933061647 1 14.58326274 -8.383247727 0.606046844 0.994372362 0.684427735 0.302126491 0.154259604 0.575489974 0.450880269 0.082216067 0.038193947 4.14E-09 8.383247727 -0.309944627 KALAT(ph)CSSHMIIVLLLFGASFYTYMLR ddPTM_HeLa_Curcumin_4h_R1 1 KALATCSSHMIIVLLLFGASFYTYMLR 27 1 Q8NGX1 Q8NGX1 OR2T34 Olfactory receptor 2T34 1 0 KALAT(0.333)CS(0.333)S(0.333)HMIIVLLLFGASFYTYMLR 40.669 0.013239 27849000 1570.7 942.29 1524.6 1326.9 1576.4 1819.5 1303.2 2204.6 1505.2 1657.4 TRUE FALSE FALSE 1446.377438 1023.737349 1581.103017 1321.409639 1557.60246 1442.11519 1339.764285 2876.772391 1340.083326 1714.994527 0.84337146 0.596933304 0.9219289 0.770503706 0.908225907 0.840886176 0.781206158 1.677423657 0.781392188 1 10.74398826 -4.257212522 24.99510362 0.877970275 1.677423973 0.828875448 0.113812489 143.7230637 849859.5499 0.017067744 0.177564742 5.53E-05 4.257212522 0.799453697 KALDSNS(ph)LENDDLSAPGREPGHFNPESR ddPTM_HeLa_Curcumin_4h_R1 1 KALDSNSLENDDLSAPGREPGHFNPESR 28 2 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 0 KALDS(0.033)NS(0.955)LENDDLS(0.012)APGREPGHFNPESR 54.263 0.0014266 20021000 1540.2 1369.4 1537.1 1386.8 1333.5 2563 1291.5 1323.8 1736.2 1574.6 TRUE FALSE FALSE 1418.291545 1487.764834 1594.066278 1381.061789 1317.598883 2031.404909 1327.736014 1727.420526 1545.743204 1629.317233 0.870482136 0.913121646 0.978364585 0.847632224 0.80868161 1.246782927 0.814903315 1.06021129 0.948706104 1 10.67005181 KALVVPEPEPDS(ph)DSNQER ddPTM_HeLa_Curcumin_4h_R1 2 KALVVPEPEPDSDSNQER 18 1 C9J0A5;C9JXC9;Q5VTR2 C9J0A5 RNF20 E3 ubiquitin-protein ligase BRE1A 1 0 KALVVPEPEPDS(0.792)DS(0.208)NQER;KALVVPEPEPDS(0.707)DS(0.293)NQER ; 101.54 0.00080449 11178000 6647.3 5575.4 5883.7 6650.5 6151.4 7796.8 7196 7008 6287 6675.5 TRUE FALSE FALSE 6121.159191 6057.312733 6101.755098 6622.981993 6078.048573 6179.655792 7397.900393 9144.706939 5597.331829 6907.473128 0.886164749 0.87692165 0.883355604 0.958814008 0.879923593 0.894633345 1.070999518 1.323885996 0.810329874 1 12.75394233 -4.367501762 2.494328616 0.929284833 1.365195659 0.840155503 0.05620463 0.119984938 1.074037348 0.007838245 0.099275586 4.29E-05 4.367501762 0.435910826 KALVVPEPEPDSDS(ph)NQER ddPTM_HeLa_Curcumin_4h_R1 1 KALVVPEPEPDSDSNQER 18 1 C9J0A5;C9JXC9;Q5VTR2 C9J0A5 RNF20 E3 ubiquitin-protein ligase BRE1A 1 0 KALVVPEPEPDS(0.069)DS(0.931)NQER 171.5 3.84E-06 25426000 4306.6 3601.9 3702.8 4041.1 3485.2 4298.2 4544.4 3776.2 4212.2 3707.5 TRUE FALSE FALSE 3965.728066 3913.232186 3840.029025 4024.378999 3443.641266 3406.704869 4671.903633 4927.545997 3750.132198 3836.335349 1.033728208 1.020044347 1.000962814 1.049016479 0.897638228 0.888010187 1.217803765 1.284440892 0.977529819 1 11.90551312 -4.635783129 6.06482649 1.002808382 1.267267594 0.796267115 0.053821436 0.066530645 3.202304094 0.007766061 0.029993569 2.31E-05 4.635783129 0.264459212 KANNS(ph)QEPSPQLASSVASTR ddPTM_HeLa_Curcumin_4h_R1 1 KANNSQEPSPQLASSVASTR 20 1 Q96HC4;Q96HC4-7;Q96HC4-4;H0Y8Y3 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 0 KANNS(0.999)QEPS(0.001)PQLASSVASTR 113.52 8.35E-05 9773300 2797.2 2149.4 2066.9 2715.7 2880.2 1516.8 1537.1 1026.1 2981 2878.5 TRUE FALSE FALSE 2575.798668 2335.184558 2143.501132 2704.463153 2845.855496 1202.198582 1580.226889 1338.953166 2653.991758 2978.527661 0.864789239 0.784006336 0.719651243 0.907986583 0.955457132 0.403621762 0.530539605 0.449535247 0.891041501 1 11.54038364 -4.252980513 0.346598245 0.960494592 1.09E-18 0.63742804 0.123876143 2.924334283 0.244753808 0.044008889 1.177739882 5.58E-05 4.252980513 -0.960494592 KANNSQEPS(ph)PQLASSVASTR ddPTM_HeLa_Curcumin_4h_R1 2 KANNSQEPSPQLASSVASTR 20 1 Q96HC4;Q96HC4-7;Q96HC4-4;H0Y8Y3 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 1 0 KANNSQEPS(1)PQLASSVASTR;KANNS(0.001)QEPS(0.999)PQLASSVASTR ; 131.04 4.06E-05 68693000 3248.8 3075.5 2833.32 2967.31 3061.4 5702.2 4296.1 2337.27 3555.8 2822.51 TRUE FALSE FALSE 2991.654052 3341.332516 2938.325332 2955.032057 3024.894804 4519.499443 4416.637004 3049.892864 3165.737636 2920.592012 1.024331382 1.144060006 1.006071824 1.011792145 1.035712894 1.547460044 1.512240321 1.044272137 1.083936963 1 11.51204512 -5.282525489 22.33408886 1.022938386 1.382415694 0.549700588 0.133389072 90.77080459 96143.12379 0.017577748 0.039365476 5.22E-06 5.282525489 0.359477309 KANT(ph)RVDLVT(ph)MVT(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 KANTRVDLVTMVTSK 15 2 H0YCQ6;E9PKY6;Q6IA69 H0YCQ6 NADSYN1 Glutamine-dependent NAD(+) synthetase 3 0 KANT(1)RVDLVT(0.999)MVT(0.5)S(0.5)K 68.809 0.010856 39549000 1557 1481.7 1813.5 1946.7 2209.8 2117.7 1832.1 1848.4 1738.8 1454.8 TRUE FALSE FALSE 1433.761807 1609.771546 1880.709905 1938.645071 2183.449578 1678.465149 1883.503795 2411.968651 1548.05799 1505.354192 0.952441502 1.069363977 1.249347108 1.287833177 1.450455707 1.114996828 1.251203076 1.602259896 1.028367941 1 10.55588726 -6.761461659 2.024094499 0.977121849 1.329425856 0.625749737 0.121175243 0.142048731 1.192647831 0.019546135 0.027994719 1.73E-07 6.761461659 0.352304007 KAPAGPSLEETSVSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 KAPAGPSLEETSVSSPK 17 1 A0A087WXZ7;K7EIX2;Q6AI08 A0A087WXZ7 HEATR6 HEAT repeat-containing protein 6 1 0 KAPAGPSLEETSVS(0.047)S(0.953)PK;KAPAGPSLEETS(0.001)VS(0.244)S(0.755)PK;KAPAGPSLEETS(0.001)VS(0.008)S(0.991)PK;KAPAGPSLEETS(0.003)VS(0.05)S(0.947)PK ;;; 175.52 8.64E-06 197905000 25535.1 21673.6 23910.7 25065.1 25169.3 24960.8 24394.8 12186.7 25090.6 22107 TRUE FALSE FALSE 23513.96989 23546.96941 24796.85158 24961.38726 24869.17254 19783.64871 25079.25243 15902.36873 22338.22395 22875.2166 1.027923377 1.029365965 1.084005105 1.091197854 1.087166647 0.864850771 1.096350381 0.695178936 0.976525134 1 14.48149778 -4.253599728 24.94186761 1.023633622 0.695178771 0.686565484 0.067509137 391.9602113 1246992.49 0.008581413 0.125203715 5.58E-05 4.253599728 -0.328454851 KAPAGQEEPGT(ph)PPS(ph)SPLSAEQLDR ddPTM_HeLa_Curcumin_4h_R1 3 KAPAGQEEPGTPPSSPLSAEQLDR 24 1 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 2 0 KAPAGQEEPGT(1)PPS(0.525)S(0.438)PLS(0.037)AEQLDR;KAPAGQEEPGT(1)PPS(0.966)S(0.033)PLS(0.001)AEQLDR;KAPAGQEEPGT(1)PPS(0.545)S(0.45)PLS(0.005)AEQLDR ;; 125.99 6.93E-07 121796000 11670.6 9474.7 9898.9 11203 9662.1 12453.6 9396.8 6312.8 11531.7 10163.8 TRUE FALSE FALSE 10746.8597 10293.65085 10265.76194 11156.64495 9546.885768 9870.582979 9660.448918 8237.543659 10266.70136 10516.99129 1.02185686 0.978763846 0.976112051 1.060820975 0.907758265 0.938536764 0.918556329 0.783260481 0.976201375 1 13.36043442 -2.943773474 0.546205709 1.009082782 3.52E-20 0.752194156 0.036056809 4.15328698 0.283210174 0.006122909 3.706144427 0.001138221 2.943773474 -1.009082782 KAPAGQEEPGT(ph)PPSS(ph)PLSAEQLDR ddPTM_HeLa_Curcumin_4h_R1 1 KAPAGQEEPGTPPSSPLSAEQLDR 24 1 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 2 0 KAPAGQEEPGT(1)PPS(0.296)S(0.643)PLS(0.061)AEQLDR 79.304 0.00020127 26234000 1935.1 1816.7 1628.3 1956.7 1928.6 2689.9 1968.5 1337.8 1933.6 1914 TRUE FALSE FALSE 1781.934793 1973.727453 1688.64623 1948.603694 1905.602705 2131.984419 2023.730812 1745.689062 1721.488918 1980.511358 0.8997347 0.99657467 0.85263143 0.983889179 0.962177115 1.076481794 1.021822371 0.881433502 0.869214363 1 10.95165726 -5.758657358 2.904184679 0.948168013 0.996980605 0.111093788 0.066776387 0.478384249 8.283332301 0.009721391 0.01994689 1.74E-06 5.758657358 0.048812592 KAPAGQEEPGT(ph)PPSSPLSAEQLDR ddPTM_HeLa_Curcumin_4h_R1 2 KAPAGQEEPGTPPSSPLSAEQLDR 24 1 P13051;Q68DM5;F5GYA2;P13051-2 P13051 UNG;DKFZp781L1143 Uracil-DNA glycosylase 1 0 KAPAGQEEPGT(0.98)PPS(0.016)S(0.003)PLS(0.001)AEQLDR;KAPAGQEEPGT(0.995)PPS(0.003)S(0.001)PLSAEQLDR ; 106.72 1.92E-06 67320000 3268.02 3013.75 2871.45 2946.26 2950.03 3835.57 3206.4 1921.11 3752.4 2864.88 TRUE FALSE FALSE 3009.352769 3274.245121 2977.868463 2934.069157 2914.852819 3040.029546 3296.362954 2506.847595 3340.771108 2964.434367 1.015152436 1.10450923 1.004531757 0.989756828 0.983274533 1.025500709 1.111970294 0.845641119 1.126950607 1 11.53354114 -6.536941868 24.9505806 1.01655505 0.999173204 0.047389681 0.075847882 1068.254148 1895277.219 0.00998455 0.014123937 2.90E-07 6.536941868 -0.017381845 KAPAPVT(ph)PPAPVQNK ddPTM_HeLa_Curcumin_4h_R1 1 KAPAPVTPPAPVQNK 15 1 Q03468;P0DP91 Q03468 ERCC6 DNA excision repair protein ERCC-6 1 0 KAPAPVT(1)PPAPVQNK 100.45 0.001993 23276000 3422.5 2438.9 2662 2895.1 2843.3 3850.4 3008.4 1722.5 3521.9 2396.2 TRUE FALSE FALSE 3151.605514 2649.707648 2760.656062 2883.120843 2809.395505 3051.783637 3092.807607 2247.682321 3135.556381 2479.467772 1.271081459 1.068659847 1.113406713 1.162798273 1.133063933 1.230822063 1.247367537 0.906518063 1.264608646 1 11.27581476 -9.627082479 1.453277566 1.000256608 1.163728555 0 0.129465977 0.449033075 1.707843664 0.070464552 0.016195687 2.36E-10 9.627082479 0.163471947 KAPEPPKTDK(ac)PGAAPPSTEER ddPTM_HeLa_Curcumin_4h_R1 1 KAPEPPKTDKPGAAPPSTEER 21 3 Q7Z3Z5;Q93074-3;Q93074;Q93074-2 Q7Z3Z5 TNRC11;MED12 Mediator of RNA polymerase II transcription subunit 12 0 1 KAPEPPK(0.002)TDK(0.998)PGAAPPSTEER 70.114 0.001194 5747300 4141.7 3138.5 3574.2 4312.7 3814.4 4581.3 3556.9 2771.5 4844.8 4427.3 FALSE TRUE FALSE 3813.880075 3409.777955 3706.662996 4294.85519 3768.915771 3631.086738 3656.697041 3616.517592 4313.337561 4581.148345 0.83251617 0.744306383 0.809112196 0.937506247 0.822701097 0.792614966 0.798205333 0.789434727 0.941540687 1 12.16149357 -8.970349467 0.667559231 1.009173871 0.814535008 0.594284946 0.050142766 0.391043574 0.30481679 0.041752228 0.01131535 1.07E-09 8.970349467 -0.194638864 S(ph)SSPELVTHLK ddPTM_HeLa_Curcumin_4h_R1 2 SSSPELVTHLK 11 0 E9PNR6;H0YE29;Q07960 E9PNR6 ARHGAP1 Rho GTPase-activating protein 1 1 0 S(0.478)S(0.478)S(0.044)PELVTHLK;S(0.426)S(0.426)S(0.148)PELVTHLK ; 210.95 6.34E-08 427650000 16970.5 13604.8 14893.8 14510.3 16066.9 18762.5 18821.3 60335 15841.3 13351.8 TRUE FALSE FALSE 15627.26702 14780.73829 15445.77733 14450.26022 15875.31271 14870.946 19349.37502 78730.86375 14103.54902 13815.77406 1.131117732 1.069845108 1.117981321 1.045924764 1.149071536 1.076374436 1.400527755 5.698621259 1.020829449 1 13.75402877 -4.259437098 4.255188448 1.077042729 6.063408143 0.998914716 0.045461401 0.006524498 0.269602075 0.008839695 0.098632911 5.50E-05 4.259437098 4.986365415 up KAPPPPIS(ph)PTQLSDVSSPR ddPTM_HeLa_Curcumin_4h_R1 2 KAPPPPISPTQLSDVSSPR 19 1 Q9P0K7-3;Q9P0K7;Q9P0K7-2 Q9P0K7-3 RAI14 Ankycorbin 1 0 KAPPPPIS(0.851)PT(0.146)QLS(0.003)DVSSPR;KAPPPPIS(0.989)PT(0.011)QLSDVSSPR ; 150.48 3.92E-07 77302000 4764.3 3793.5 3938.4 4423.7 4075.1 4839.5 3306.3 3489.9 4470.6 4304.4 TRUE FALSE FALSE 4387.200628 4121.393236 4084.360569 4405.395902 4026.507094 3835.733148 3399.06588 4553.954444 3980.186365 4453.97758 0.985007344 0.925328689 0.917014173 0.989092518 0.904025003 0.861192738 0.763152894 1.022446648 0.893625146 1 12.12087858 -6.451199368 0.580906193 0.997811441 0.873448655 0.022433171 0.073039428 0.690688101 0.465800877 0.015802359 0.036566082 3.54E-07 6.451199368 -0.124362786 KAQAVSEEEEEEEGKS(ph)S(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 KAQAVSEEEEEEEGKSSSPK 20 2 Q9GZR7-2;Q9GZR7;G3V529 Q9GZR7-2 DDX24 ATP-dependent RNA helicase DDX24 2 0 KAQAVS(0.016)EEEEEEEGKS(0.853)S(0.851)S(0.28)PK 75.239 0.0031686 17043000 5382.4 4836.6 4807.9 5220.5 4786.6 5136.2 4174.3 2450.9 5148.6 4481.3 TRUE FALSE FALSE 4956.377361 5254.654153 4986.085003 5198.898954 4729.522921 4070.894223 4291.419623 3198.168127 4583.811461 4637.024841 1.068870133 1.13319517 1.07527675 1.121171254 1.019947721 0.877910808 0.925468327 0.689702608 0.988524241 1 12.17898374 -4.180427373 0.909385324 1.050083192 0.478732242 0.790574176 0.057724855 0.869474558 0.486018322 0.009606026 0.508065271 6.60E-05 4.180427373 -0.57135095 KAQCPIVER ddPTM_HeLa_Curcumin_4h_R1 2 KAQCPIVER 9 1 M0R0F0;M0R0R2;P46782 M0R0F0 RPS5 "40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed" 0 0 ; ; 80.231 0.012049 10259900 6767.7 4630.7 5200 5127.6 5456.7 6355.2 3746.3 4523.4 5767 6034.7 FALSE FALSE TRUE 6232.029404 5030.957074 5392.716574 5106.38335 5391.632416 5037.059882 3851.411095 5902.563837 5134.374528 6244.405376 0.99801807 0.805674323 0.863607702 0.81775334 0.863434081 0.806651647 0.616777878 0.945256351 0.822235941 1 12.60834848 -7.263016829 23.31973771 0.999064098 0.812526553 0.186617622 0.096184489 28.28949444 418209.0996 0.012406936 0.014596427 5.46E-08 7.263016829 -0.186537545 KAS(ph)GS(ph)ENEGDYNPGR ddPTM_HeLa_Curcumin_4h_R1 1 KASGSENEGDYNPGR 15 1 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 2 0 KAS(0.638)GS(0.802)ENEGDY(0.56)NPGR 85.473 0.017446 24013000 6703.3 4191.6 6204.9 7778.2 7175.4 6693.7 4697.8 4056.5 6829.7 6261.4 TRUE FALSE FALSE 6172.726732 4553.903227 6434.859052 7746.015869 7089.838041 5305.351166 4829.607625 5293.308176 6080.498997 6478.983184 0.952730785 0.702873136 0.993189652 1.195560422 1.094282519 0.818855523 0.745426788 0.816996746 0.938495876 1 12.6615517 -5.103439952 6.413846506 0.98053647 0.781433558 0.347370183 0.119167971 0.206292518 10.86101794 0.017582024 0.045598212 7.88E-06 5.103439952 -0.199102912 KAS(ph)GSENEGDYNPGR ddPTM_HeLa_Curcumin_4h_R1 1 KASGSENEGDYNPGR 15 1 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 1 0 KAS(0.861)GS(0.139)ENEGDYNPGR 145.55 0.0007668 3657500 780.96 545.9 545.63 878.07 776.18 765.56 447.17 668.03 730.26 555.55 TRUE FALSE FALSE 719.1461919 593.0851635 565.8515278 874.436779 766.9245604 606.7742264 459.7163867 871.7092718 650.152305 574.8553211 1.251003801 1.031712053 0.984337288 1.521142358 1.334117529 1.05552511 0.799707978 1.516397674 1.130984234 1 9.167055096 -9.481745824 1.093658697 0.994819035 1.181652806 0.032374554 0.222246717 1.148563929 2.343908855 0.172109829 0.037560784 3.30E-10 9.481745824 0.186833771 KAS(ph)PEAASTPRDPIDVDLPEEAER ddPTM_HeLa_Curcumin_4h_R1 1 KASPEAASTPRDPIDVDLPEEAER 24 2 P29590;P29590-5;P29590-4;P29590-9;P29590-3;P29590-8;H3BVD2;H3BT29;P29590-2 P29590;P29590-2 PML Protein PML 1 0 KAS(0.868)PEAAS(0.066)T(0.066)PRDPIDVDLPEEAER 66.041 0.0004224 80530000 1839.1 1218.7 1288.6 1267 1246.1 1670.6 1326.5 943.49 1440.4 1269 TRUE FALSE FALSE 1693.533294 1324.038998 1336.35665 1261.75749 1231.241071 1324.098728 1363.71802 1231.155758 1282.391724 1313.097656 1.289723797 1.008332466 1.017713073 0.960901487 0.937661465 1.008377955 1.038550343 0.937596494 0.976615653 1 10.3587585 -7.032062733 24.0213073 1.137456884 0.986414107 0.16313567 0.088057144 375.6365723 281425.1401 0.018197936 0.022301263 9.29E-08 7.032062733 -0.151042777 KAS(ph)PEPEGEAAGK ddPTM_HeLa_Curcumin_4h_R1 3 KASPEPEGEAAGK 13 1 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 0 KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK;KAS(1)PEPEGEAAGK ;; 121.13 0.0029296 129030000 16943.3 13962.8 15530.4 15412.1 15217.8 18283 15007 9129.9 17445.4 15632 TRUE FALSE FALSE 15602.21993 15169.68221 16105.97029 15348.32881 15036.33767 14490.89971 15428.05603 11913.56448 15531.68327 16175.21084 0.964575985 0.937835208 0.995719342 0.948879676 0.929591449 0.895870839 0.953808651 0.736532253 0.960215197 1 13.9814969 -3.191294834 0.710982888 0.97728701 4.65E-41 0.763409076 0.034686547 3.646659989 0.41860226 0.005618536 4.09139224 0.000643732 3.191294834 -0.97728701 KAS(ph)PEPPDSAEGALK ddPTM_HeLa_Curcumin_4h_R1 5 KASPEPPDSAEGALK 15 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 0 KAS(0.995)PEPPDS(0.005)AEGALK;KAS(1)PEPPDSAEGALK;KAS(1)PEPPDSAEGALK;KAS(0.997)PEPPDS(0.003)AEGALK;KAS(0.999)PEPPDS(0.001)AEGALK ;;;; 120.71 0.00059516 929681000 30195.4 24208.6 27297.1 27117.5 27894.6 31165.7 26597.8 22169.6 28473.8 24705.7 TRUE FALSE FALSE 27805.40223 26301.08351 28308.75454 27005.29497 27561.97511 24701.58251 27344.06268 28929.00898 25350.29538 25564.22124 1.087668659 1.028823967 1.107358377 1.056370727 1.078146479 0.966256014 1.069622361 1.131620976 0.991631826 1 14.64183846 -9.43893535 1.102794004 0.999037742 1.065096433 0.296943038 0.042693988 0.596391323 1.266566683 0.031071525 0.007314923 3.64E-10 9.43893535 0.066058691 KAS(ph)PEPPDSAEGALKLGEEQQR ddPTM_HeLa_Curcumin_4h_R1 1 KASPEPPDSAEGALKLGEEQQR 22 2 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 0 KAS(0.893)PEPPDS(0.107)AEGALKLGEEQQR 98.804 0.0001016 23710000 2946 2068 1902.9 2126.9 1191 2634.4 1737.1 1541.5 3404.3 2376.5 TRUE FALSE FALSE 2712.820991 2246.748705 1973.423148 2118.099451 1176.798103 2087.995744 1785.838351 2011.496254 3030.856807 2459.083198 1.103183899 0.913652985 0.802503612 0.861337043 0.478551561 0.849095202 0.7262212 0.817986254 1.232514951 1 11.26390483 -6.828177395 1.858195016 1.048736988 0.73967746 0.631638822 0.119173082 0.150845207 1.06091908 0.017610971 0.024721715 1.49E-07 6.828177395 -0.309059528 LS(ph)LDLSHR ddPTM_HeLa_Curcumin_4h_R1 1 LSLDLSHR 8 0 Q8TDM6-4;Q8TDM6;A0A0A0MSL1;Q8TDM6-2;A0A0J9YYG8 Q8TDM6-4 DLG5 Disks large homolog 5 1 0 LS(1)LDLSHR 94.409 0.004858 0 2614.8 2294.3 2572.4 2561.3 3293.9 3647.5 1526.5 51.643 3106.7 2689.8 TRUE FALSE FALSE 2407.835821 2492.609069 2667.735407 2550.702019 3254.622394 2890.967384 1569.329482 67.38871296 2765.902783 2783.27035 0.865110291 0.895568434 0.9584895 0.916440625 1.169351872 1.038694421 0.563843711 0.024212062 0.993760014 1 11.44256533 -4.437480759 2.687488106 0.953882674 7.51E-18 0.91818248 0.088740974 0.074004044 0.865290119 0.014005092 0.129097627 3.65E-05 4.437480759 -0.953882674 down KASAISIK(ac)LGSSKPK ddPTM_HeLa_Curcumin_4h_R1 2 KASAISIKLGSSKPK 15 3 Q8WW12;Q8WW12-2 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 0 1 ; KASAISIK(1)LGSSKPK;KASAISIK(1)LGSSKPK 119.87 0.00013643 11288900 8612.9 7791.3 7390.1 7537.7 5891 13325.1 9539.8 9829.7 8661.8 8709.7 FALSE TRUE FALSE 7931.179877 8464.745255 7663.983607 7506.510995 5820.753673 10561.32406 9807.461113 12826.73028 7711.622211 9012.361427 0.88003349 0.939237216 0.850385736 0.832912778 0.64586332 1.171870895 1.088223236 1.423237448 0.855671654 1 13.13768946 -4.424776436 1.43782116 0.913055041 1.509647732 0.660745926 0.119554285 0.450410264 1.040602119 0.01792946 0.350891465 3.76E-05 4.424776436 0.596592691 VS(ph)PPASPTLEVELGSAELPLQGAVGPELPPGGGHGR ddPTM_HeLa_Curcumin_4h_R1 2 VSPPASPTLEVELGSAELPLQGAVGPELPPGGGHGR 36 0 Q7Z6J0 Q7Z6J0 SH3RF1 E3 ubiquitin-protein ligase SH3RF1 1 0 VS(0.995)PPAS(0.004)PT(0.001)LEVELGSAELPLQGAVGPELPPGGGHGR;VS(0.857)PPAS(0.1)PT(0.043)LEVELGSAELPLQGAVGPELPPGGGHGR ; 132.47 2.57E-18 23983000 1917.9 1825.92 1569.44 1747.92 1851.13 1987.96 1130.26 491.11 1913.37 1792.52 TRUE FALSE FALSE 1766.096191 1983.744389 1627.604827 1740.68757 1829.056484 1575.634687 1161.972054 640.8471782 1703.478098 1854.809937 0.952170978 1.069513566 0.87750491 0.938472205 0.986115314 0.849485792 0.626464216 0.345505577 0.918411134 1 10.85705565 -4.430418348 1.262943928 0.976276082 0.17050564 0.939254677 0.050329381 0.154653252 0.257572554 0.006839065 0.148184636 3.71E-05 4.430418348 -0.805770442 down KASGPPVSELITK ddPTM_HeLa_Curcumin_4h_R1 2 KASGPPVSELITK 13 1 P10412;P16403;P16402 P10412;P16403;P16402 HIST1H1E;HIST1H1C;HIST1H1D Histone H1.4;Histone H1.2;Histone H1.3 0 0 ; ; 146 0.00010391 13375600 21122.2 13795.7 16443.6 19777.7 18844 22032 18618.7 14813.2 23882 17648.3 FALSE FALSE TRUE 19450.35558 14988.13884 17053.01428 19695.86512 18619.29761 17462.31485 19141.09061 19329.67649 21262.20435 18261.57711 1.065097251 0.82074723 0.933819362 1.0785413 1.019588697 0.956232572 1.048161968 1.05848889 1.164313696 1 14.15652374 -3.323405243 13.78294932 1.012118464 1.013273656 0 0.089392996 0 0 0.010272067 0 0.000474892 3.323405243 0.001155192 KASGS(ph)ENEGDYNPGR ddPTM_HeLa_Curcumin_4h_R1 1 KASGSENEGDYNPGR 15 1 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 1 0 KAS(0.405)GS(0.593)ENEGDY(0.002)NPGR 149.19 0.00071158 4483000 1875.3 1051.3 1810.1 1992.8 2146.3 2135 1676 1558.2 2199.9 1725.7 TRUE FALSE FALSE 1726.868026 1142.169687 1877.183898 1984.554322 2120.706774 1692.176934 1723.024049 2033.288007 1958.576474 1785.667947 0.96707119 0.639631623 1.051250263 1.11137926 1.187626612 0.947643674 0.964918507 1.138670832 1.096831288 1 10.80224811 -6.556232808 24.99995672 0.952787141 1.065677293 0.211790216 0.129468457 262.4138479 196686.9066 0.01971939 0.027887533 2.78E-07 6.556232808 0.112890151 LEQLCEEFS(ph)EEERVR ddPTM_HeLa_Curcumin_4h_R1 2 LEQLCEEFSEEERVR 15 1 Q9H3C7-3;Q9H3C7 Q9H3C7-3 GGNBP2 Gametogenetin-binding protein 2 1 0 LEQLCEEFS(1)EEERVR;LEQLCEEFS(1)EEERVR ; 161.91 0.0011962 4199100 1843.03 1268.24 1547.94 1469.5 1758.21 2032.16 1153.24 503.87 1943.9 1659.5 TRUE FALSE FALSE 1697.152231 1377.861014 1605.308018 1463.419598 1737.244494 1610.667109 1185.596811 657.4976435 1730.659033 1717.167501 0.98834402 0.802403384 0.934858141 0.8522288 1.011691924 0.937979031 0.690437485 0.382896627 1.007856853 1 10.74581506 -4.430415459 1.869314896 0.966523195 0.301240988 0.865272525 0.068902105 0.149222601 0.689172829 0.010589828 0.152760951 3.71E-05 4.430415459 -0.665282207 down SDGS(ph)LEDGDDVHR ddPTM_HeLa_Curcumin_4h_R1 2 SDGSLEDGDDVHR 13 0 Q9NRX5 Q9NRX5 SERINC1 Serine incorporator 1 1 0 SDGS(1)LEDGDDVHR;SDGS(1)LEDGDDVHR ; 193.11 5.95E-06 17575000 4299.5 3777.6 3373.6 4002.5 3519.8 3858.5 2135.35 781.56 4393.8 3667 TRUE FALSE FALSE 3959.190038 4104.118911 3498.628584 3985.938716 3477.828684 3058.203606 2195.262174 1019.854046 3911.811133 3794.427977 1.043422108 1.081617292 0.922043745 1.05047157 0.91656205 0.805972237 0.578548911 0.268776757 1.030935666 1 11.8896667 -4.427702896 0.964946357 1.021940333 4.51E-18 0.970818763 0.042038833 0.166131693 0.13992236 0.0062488 0.165311931 3.74E-05 4.427702896 -1.021940333 down ATSAGS(ph)SPSCSLAGR ddPTM_HeLa_Curcumin_4h_R1 2 ATSAGSSPSCSLAGR 15 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 0 ATSAGS(0.498)S(0.498)PS(0.003)CSLAGR;ATSAGS(0.499)S(0.499)PS(0.002)CS(0.001)LAGR ; 201.76 2.43E-09 139907000 12224.6 10420.2 11053.8 11467.8 9783.8 11655.9 6496.3 1732.26 12208.3 10503.8 TRUE FALSE FALSE 11257.01001 11320.87566 11463.46355 11420.34928 9667.134575 9238.334951 6678.568694 2260.4181 10869.08003 10868.80627 1.035717238 1.041593288 1.05471229 1.050745501 0.889438484 0.849986164 0.614471224 0.207972987 1.000025188 1 13.40790588 -4.425491043 1.129205507 1.021769187 4.75E-16 0.977557812 0.03853436 0.126307474 0.157243492 0.005898925 0.141737903 3.75E-05 4.425491043 -1.021769187 down KASTAPGAEAS(ph)PS(ph)PCITERSKQK ddPTM_HeLa_Curcumin_4h_R1 1 KASTAPGAEASPSPCITERSKQK 23 3 Q66PJ3 Q66PJ3 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 2 0 KAS(0.061)T(0.061)APGAEAS(0.878)PS(0.957)PCIT(0.033)ERS(0.01)KQK 58.914 0.006986 59086000 920.15 663.61 966.12 918.79 964.92 1153.7 1109.1 381.97 1040.8 698.37 TRUE FALSE FALSE 847.3191566 720.9694914 1001.925257 914.9882904 953.4139592 914.4096151 1140.218361 498.4308946 926.626844 722.6383055 1.172535624 0.997690665 1.386482351 1.266177399 1.319351537 1.265376618 1.577854858 0.689737716 1.282283041 1 9.497129921 -8.095075729 0.531207834 1.008964871 1.256557923 0 0.23848492 1.13303336 0.740347557 0.117487963 0.066969044 8.03E-09 8.095075729 0.247593052 LTESCCS(ph)SDAFER ddPTM_HeLa_Curcumin_4h_R1 2 LTESCCSSDAFER 13 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 0 LTES(0.002)CCS(0.944)S(0.054)DAFER;LTES(0.001)CCS(0.5)S(0.5)DAFER ; 185.2 6.51E-05 24243000 3380.2 2880.3 3350.5 3302.3 3471.1 3434.1 2205.42 979.87 3445.7 2686.7 TRUE FALSE FALSE 3112.653603 3129.260298 3474.672477 3288.635958 3429.7094 2721.82895 2267.29815 1278.627852 3067.715331 2780.062625 1.119634348 1.125607844 1.249854031 1.182935927 1.233680626 0.979053107 0.815556502 0.459927716 1.103469865 1 11.44090167 -4.422234479 1.70116053 1.097252759 0.356039253 0.87064047 0.081236433 0.223524898 0.797731096 0.014641128 0.242002526 3.78E-05 4.422234479 -0.741213506 down KATATISAK(ac)PQITNPK ddPTM_HeLa_Curcumin_4h_R1 2 KATATISAKPQITNPK 16 2 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 0 1 ; KATATISAK(1)PQITNPK;K(0.001)ATATISAK(0.999)PQITNPK 149.22 0.00086051 11346100 7194.3 5776.5 5871.1 5987.8 6376.5 8227.6 6826.5 8767.1 7557.6 7074.1 FALSE TRUE FALSE 6624.863564 6275.79492 6088.688131 5963.02407 6300.464402 6521.103016 7018.033217 11440.14843 6728.550188 7319.924448 0.905045347 0.857357882 0.831796581 0.814629183 0.860728064 0.890870263 0.958757603 1.562877938 0.919210333 1 12.83761304 -4.261520021 4.606919333 0.91834375 1.60308574 0.923925193 0.057359581 0.049188555 2.747792476 0.010662045 0.108406378 5.48E-05 4.261520021 0.68474199 KAVLFCLSEDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 KAVLFCLSEDKK 12 2 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 1 KAVLFCLSEDK(1)K 177.42 6.20E-10 5797100 4144.9 4418.3 3286.3 3325.4 6439.6 10850 7311.7 6984.9 9717.4 4699.1 FALSE TRUE FALSE 3816.826791 4800.198164 3408.093169 3311.640376 6362.811976 8599.587695 7516.846624 9114.563855 8651.425532 4862.393375 0.784968738 0.987208931 0.700908566 0.681072081 1.308576144 1.768591521 1.545914952 1.874501537 1.779252492 1 12.2474509 -5.516180099 3.600814009 0.874199583 1.703143239 0.505691363 0.314624155 0.055683781 1.547018278 0.020773793 0.0464046 3.05E-06 5.516180099 0.828943655 KAVLFCLSEDKK ddPTM_HeLa_Curcumin_4h_R1 1 KAVLFCLSEDKK 12 2 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 0 68.676 0.019406 4034300 1487.7 1144.8 1316.7 1472.6 1316 1866.5 1329.7 1401 1614.2 1636.8 FALSE FALSE TRUE 1369.946975 1243.751411 1365.49806 1466.506771 1300.30756 1479.36686 1367.007803 1828.158451 1437.126299 1693.678678 0.808858842 0.734349099 0.806232066 0.865870717 0.767741589 0.873463709 0.807123465 1.079400995 0.848523582 1 10.72594448 -9.238244245 1.011622461 0.998410498 0.83578759 0.010136466 0.099829201 0.48080424 0.895662513 0.054644106 0.015674835 5.78E-10 9.238244245 -0.162622908 KAVPMAPAPAS(ph)PGSSNDSSAR ddPTM_HeLa_Curcumin_4h_R1 4 KAVPMAPAPASPGSSNDSSAR 21 1 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 0 KAVPMAPAPAS(0.931)PGS(0.022)S(0.008)NDS(0.013)S(0.026)AR;KAVPMAPAPAS(0.877)PGS(0.021)S(0.006)NDS(0.048)S(0.048)AR;KAVPMAPAPAS(0.844)PGS(0.044)S(0.066)NDS(0.023)S(0.023)AR;KAVPMAPAPAS(0.993)PGS(0.004)S(0.001)NDS(0.001)S(0.001)AR ;;; 115.06 5.77E-06 111050800 11262.8 7861 8553.5 10443.6 7921.4 11045.4 7607 7798.8 12495.4 9652.4 TRUE FALSE FALSE 10371.3375 8540.469812 8870.500234 10400.38715 7826.942479 8754.459533 7820.431947 10176.61822 11124.68588 9987.820182 1.0383985 0.855088463 0.888131752 1.041307008 0.783648718 0.876513531 0.782996871 1.018902827 1.113825207 1 13.28595413 -7.265115813 24.92982774 1.018132627 0.888937129 0.401573983 0.085798572 233.7907293 1585328.422 0.012866409 0.015019238 5.43E-08 7.265115813 -0.129195497 KAVTK(ac)AQK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 KAVTKAQKK 9 3 P58876;P62807;P57053;O60814;Q16778;P06899;Q8N257;Q93079;U3KQK0;Q99877;Q99880 P58876;P62807;Q16778;Q8N257;Q93079;U3KQK0;Q99880 HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BL Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-L 0 2 KAVTK(1)AQK(1)K 123.62 6.59E-10 0 8401.5 2210.7 5642.4 2880.4 5330.5 6144.3 3564.4 1870 4552.9 7210 FALSE TRUE FALSE 7736.51241 2401.783057 5851.512308 2868.481668 5266.937269 4869.902919 3664.407471 2440.154392 4053.458261 7460.546963 1.036989975 0.32193123 0.784327521 0.384486779 0.705972001 0.65275414 0.491171423 0.327074463 0.54331918 1 12.86506569 -7.276761931 24.95058416 1.017467506 0.539302484 0.266197784 0.210894686 289.3994418 471244.6109 0.023427358 0.026842623 5.29E-08 7.276761931 -0.478165022 KAVVLPGGTATS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 KAVVLPGGTATSPK 14 1 Q8N1G0;Q8N1G0-2;H0Y5I5;F8WCX2 Q8N1G0 ZNF687 Zinc finger protein 687 1 0 KAVVLPGGTAT(0.121)S(0.879)PK;KAVVLPGGT(0.001)AT(0.111)S(0.888)PK ; 155.92 0.00017969 163373000 12748.4 10057.9 9988.9 11655.9 10062 12618.6 11389.4 5226.8 12648.9 11486.7 TRUE FALSE FALSE 11739.35069 10927.26006 10359.09742 11607.67097 9942.017222 10001.36012 11708.95591 6820.427259 11261.34732 11885.86197 0.987673483 0.919349399 0.871547848 0.976594798 0.836457402 0.841450132 0.985116262 0.573826894 0.947457353 1 13.53695891 -2.792285338 0.352876697 0.994436961 1.02E-22 0.502014699 0.085769275 8.940413969 0.349236867 0.023520093 4.726518004 0.001613298 2.792285338 -0.994436961 KAVVVCPK ddPTM_HeLa_Curcumin_4h_R1 2 KAVVVCPK 8 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PRZ7;A0A1W2PQD4;A0A1W2PQ74 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 0 ; ; 107.66 0.0011272 4520900 15575.8 12623.6 14767.9 13542.5 14564.8 17381.1 13822.1 12346.6 15062 13702 FALSE FALSE TRUE 14342.95899 13714.72773 15315.21137 13486.46472 14391.12427 13776.06393 14209.91093 16111.0215 13409.73628 14178.14348 1.011624619 0.96731478 1.080198644 0.951215139 1.015021769 0.971640889 1.002240593 1.136328006 0.945803398 1 13.79138101 -4.261331015 23.0472044 1.002625493 1.136328107 0.55068016 0.037865491 1.364429841 288937.5751 0.003988882 0.030785805 5.48E-05 4.261331015 0.133702613 KAYFLYMY(ph)SRY(ph)LS(ph)GEK ddPTM_HeLa_Curcumin_4h_R1 1 KAYFLYMYSRYLSGEK 16 2 Q9UJX2 Q9UJX2 CDC23 Cell division cycle protein 23 homolog 3 0 KAY(0.047)FLY(0.046)MY(0.595)S(0.403)RY(0.924)LS(0.985)GEK 46.543 0.016756 28184000 467.54 641.42 572.05 639.42 714.61 667.76 611.96 590.03 665.43 592.15 TRUE FALSE FALSE 430.5337157 696.8614867 593.2506762 636.7742495 706.0887425 529.2590488 629.1299506 769.9274308 592.4339938 612.7271684 0.702651584 1.137311225 0.968213435 1.039245985 1.152370547 0.863776043 1.026770124 1.256558335 0.96688057 1 9.259101012 -7.247659266 24.93014179 0.859585467 1.053196662 0.274471689 0.125745277 732.8932561 1325906.699 0.024008711 0.029323788 5.65E-08 7.247659266 0.193611195 KAYS(ph)FCGTVEYMAPEVVNR ddPTM_HeLa_Curcumin_4h_R1 1 KAYSFCGTVEYMAPEVVNR 19 1 B4DG22;B1AXG1;B7ZB17;P51812;Q9UK32-2;Q9UK32;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA6;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase alpha-6;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 0 KAY(0.183)S(0.774)FCGT(0.029)VEY(0.014)MAPEVVNR 62.028 0.0091112 118550000 2125.5 1996.3 1703.2 1774.3 1406.7 2501.8 2079.7 1630.1 1952.4 2029.7 TRUE FALSE FALSE 1957.264432 2168.851277 1766.32209 1766.958417 1389.926021 1982.898479 2138.050785 2127.109986 1738.226605 2100.231924 0.93192776 1.032672274 0.841012876 0.841315855 0.661796445 0.944133101 1.018006993 1.012797664 0.827635551 1 11.03633293 -6.753891465 24.99514941 0.971817913 0.882838238 0.054074248 0.108686397 264.8064531 876911.7062 0.016779662 0.023467408 1.76E-07 6.753891465 -0.088979676 VTNDIS(ph)PESS(ph)PGVGR ddPTM_HeLa_Curcumin_4h_R1 4 VTNDISPESSPGVGR 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 2 0 VTNDIS(1)PES(0.01)S(0.99)PGVGR;VTNDIS(0.999)PES(0.004)S(0.997)PGVGR;VTNDIS(1)PES(0.001)S(1)PGVGR;VT(0.001)NDIS(0.999)PES(0.171)S(0.829)PGVGR ;;; 147.53 0.0011163 284037000 24441.4 19332.2 21839.1 22291 20499.8 22172.8 12184.9 4422.07 24370.7 20768.9 TRUE FALSE FALSE 22506.8374 21003.18923 22648.47626 22198.76575 20255.35327 17573.91134 12526.7755 5770.338786 21697.29518 21490.61773 1.047286666 0.977319009 1.053877396 1.032951497 0.942520756 0.817748078 0.582895087 0.268505022 1.009617102 1 14.39141933 -4.420124653 1.028005497 1.023657197 1.76E-17 0.989801469 0.024567502 0.103327631 0.101012861 0.004173247 0.108458591 3.80E-05 4.420124653 -1.023657197 down KCSTPEEIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 KCSTPEEIKK 10 2 P60981;F6RFD5;P60981-2 P60981 DSTN Destrin 0 1 KCSTPEEIK(1)K 120.03 0.00065908 2718200 1301.8 2016.3 1225.2 1164.6 2613.5 3269 2713.3 2230.6 2431.2 1521.4 FALSE TRUE FALSE 1198.761156 2190.579988 1270.60699 1159.781194 2582.335719 2590.972551 2789.427896 2910.699672 2164.503443 1574.268537 0.761471838 1.391490674 0.807109435 0.736711156 1.640340043 1.645826293 1.771888233 1.848921962 1.374926445 1 10.62046594 -5.705325007 6.257023822 0.910846461 1.733366132 0.681473204 0.23363007 0.06319865 5.10722225 0.027730209 0.055516205 1.97E-06 5.705325007 0.822519671 KDAPT(ph)SPASVASSSSTPSSK ddPTM_HeLa_Curcumin_4h_R1 3 KDAPTSPASVASSSSTPSSK 20 1 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 0 KDAPT(0.557)S(0.438)PAS(0.005)VASSSSTPSSK;KDAPT(0.56)S(0.424)PAS(0.013)VAS(0.002)S(0.001)SSTPSSK;KDAPT(0.528)S(0.375)PAS(0.093)VAS(0.003)S(0.001)SSTPSSK ;; 78.708 0.0015315 42473300 12114.2 10460.4 10756.3 10095.9 10581.8 12231.4 10089.7 9600 12199.7 11214.4 TRUE FALSE FALSE 11155.34829 11364.55037 11154.93794 10054.12584 10455.61895 9694.469764 10372.78983 12526.99581 10861.42343 11604.09957 0.961328212 0.979356503 0.96129285 0.866428781 0.901028028 0.8354349 0.893890109 1.079531913 0.935998814 1 13.50234696 -6.455920903 6.090870225 0.980619432 0.908912825 0.13533832 0.062732575 0.253632298 17.9016411 0.009262804 0.014130588 3.50E-07 6.455920903 -0.071706607 KDAS(ph)SSPASTASSASSTSLK ddPTM_HeLa_Curcumin_4h_R1 1 KDASSSPASTASSASSTSLK 20 1 A0A669KBK8;Q04724 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 0 KDAS(0.328)S(0.328)S(0.328)PAS(0.01)T(0.005)ASSASSTSLK 53.481 0.012726 19072000 1954.6 2430.3 2356.9 2743.4 1843.4 2782.4 2146.6 1352.1 2663.1 3278.2 TRUE FALSE FALSE 1799.891348 2640.364303 2444.248787 2732.048538 1821.418659 2205.298876 2206.827819 1764.349066 2370.964593 3392.117206 0.530610011 0.778382391 0.720567315 0.805411008 0.536956287 0.65012461 0.650575344 0.520132106 0.698963051 1 11.7279703 -9.433831128 1.053875353 1.009010547 0.645887995 0.135685535 0.131169972 0.277610513 0.5290254 0.077951058 0.017660923 3.68E-10 9.433831128 -0.363122552 KDDEENYLDLFSHK ddPTM_HeLa_Curcumin_4h_R1 2 KDDEENYLDLFSHK 14 1 Q07666-2;Q07666;Q07666-3 Q07666-2 KHDRBS1 "KH domain-containing, RNA-binding, signal transduction-associated protein 1" 0 0 ; ; 141.46 0.00021175 100514000 10225.7 8643 8839.2 9615.2 9326.6 10445.6 8599.4 8166.8 9543.8 7510.3 FALSE FALSE TRUE 9416.325055 9390.062408 9166.788528 9575.41485 9215.386386 8279.064814 8840.67602 10656.81972 8496.869017 7771.282366 1.21168227 1.208302821 1.179572186 1.232153768 1.185825704 1.065340882 1.13760839 1.371307749 1.093367686 1 12.92393697 -9.227225978 0.803499984 0.990523381 1.194111643 0.352783697 0.078283745 0.475564356 0.512815947 0.061734181 0.014382627 5.93E-10 9.227225978 0.203588263 KDDEVQVVR ddPTM_HeLa_Curcumin_4h_R1 1 KDDEVQVVR 9 1 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;Q9UNX3;P61254;J3QRC4 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 0 0 109.66 0.0010701 9179100 3777.2 3032 3480.3 3716.1 4187.8 4970.2 3488.6 3672.1 3696.3 3589.9 FALSE FALSE TRUE 3478.230634 3294.07257 3609.28298 3700.723763 4137.86322 3939.324494 3586.480727 4791.706386 3290.825138 3714.648758 0.936355188 0.886779016 0.971635063 0.996251329 1.113931219 1.06048371 0.965496595 1.289948713 0.885904793 1 11.85901009 -5.887600075 3.771452093 0.962343616 1.094051148 0.464581119 0.083898065 0.182377426 4.936736709 0.011493637 0.021664089 1.30E-06 5.887600075 0.131707532 KDDS(ph)DDDGGGWITPSNIK ddPTM_HeLa_Curcumin_4h_R1 1 KDDSDDDGGGWITPSNIK 18 1 Q9ULX3 Q9ULX3 NOB1 RNA-binding protein NOB1 1 0 KDDS(1)DDDGGGWITPSNIK 96.181 0.00091956 217850000 3974.5 3782.1 3643.2 3318.8 4629.1 4449.5 3526.2 2950.2 3392.1 3715.8 TRUE FALSE FALSE 3659.914131 4109.007871 3778.220197 3305.067685 4573.901006 3526.623544 3625.135682 3849.702399 3019.995117 3844.923773 0.951882104 1.068683832 0.982651522 0.859592512 1.189594716 0.917215464 0.942836814 1.00124284 0.785449932 1 11.90873928 TAEK(ac)TSLSFK ddPTM_HeLa_Curcumin_4h_R1 2 TAEKTSLSFK 10 1 H0Y612;Q9UPN9-2;Q9UPN9 H0Y612 TRIM33 E3 ubiquitin-protein ligase TRIM33 0 1 ; TAEK(1)TSLSFK;TAEK(1)TSLSFK 201.84 2.74E-26 154162000 10746.2 7072.7 10129.1 9101.4 8770.6 12412.6 12057.9 15168.4 8655.6 7745.5 FALSE TRUE FALSE 9895.626931 7684.032673 10504.49336 9063.740818 8666.016323 9838.086841 12396.21222 19793.17533 7706.102335 8014.655548 1.234691481 0.958747712 1.310660613 1.130895865 1.081271213 1.227512122 1.546693073 2.469622707 0.961501376 1 12.9684248 -4.154219899 1.508655315 1.115881281 3.26662362 0.935636203 0.108688152 0.252719299 0.429936319 0.016024472 0.868294505 7.01E-05 4.154219899 2.15074234 up KDEWGLVAPIS(ph)PGPLTPMR ddPTM_HeLa_Curcumin_4h_R1 2 KDEWGLVAPISPGPLTPMR 19 1 A0A669KB77;P11137-3;P11137;E7EV03 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 KDEWGLVAPIS(1)PGPLTPMR;KDEWGLVAPIS(0.991)PGPLT(0.009)PMR ; 119.25 0.00011536 277370000 6377.2 5407.9 5745.3 5338.4 5833.8 5790 4702.8 4361.07 6161.3 5300.49 TRUE FALSE FALSE 5872.437891 5875.334779 5958.225872 5316.311115 5764.235745 4589.088733 4834.747911 5690.740167 5485.420805 5484.681633 1.070698043 1.071226221 1.086339421 0.969301679 1.05096998 0.836710139 0.881500192 1.037569826 1.00013477 1 12.42119216 -5.2818281 24.93000094 1.037172003 0.914884063 0.45349771 0.058761251 482.2312909 589640.2863 0.008352735 0.018697915 5.23E-06 5.2818281 -0.12228794 KDEWGLVAPISPGPLT(ph)PMR ddPTM_HeLa_Curcumin_4h_R1 1 KDEWGLVAPISPGPLTPMR 19 1 A0A669KB77;P11137-3;P11137;E7EV03 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 KDEWGLVAPIS(0.287)PGPLT(0.713)PMR 64.275 0.011749 82087000 4510.3 3390.6 3720.8 3615.8 4094.9 3988.8 3649.4 3481.5 4767.4 3680.1 TRUE FALSE FALSE 4153.304996 3683.668356 3858.696121 3600.838778 4046.070992 3161.477917 3751.792342 4542.993323 4244.428147 3807.983201 1.090683644 0.967354151 1.013317527 0.94560259 1.06252333 0.830223704 0.985243932 1.193018215 1.114613149 1 11.8948114 -7.244640236 24.48981386 1.042822835 0.993413903 0.084107002 0.091627111 1454.383689 2120203.442 0.014699668 0.017975412 5.69E-08 7.244640236 -0.049408932 KDGADFAK(ac)WR ddPTM_HeLa_Curcumin_4h_R1 1 KDGADFAKWR 10 2 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7;H3BR04;H3BMQ8;H3BU78;P09972;K7EKH5;C9J8F3;J3KSV6;J3QKP5;A8MVZ9 P04075;P09972 ALDOA;ALDOC Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase;Fructose-bisphosphate aldolase C 0 1 KDGADFAK(1)WR 90.149 0.0049269 6163300 3278.4 4048.4 2265.2 2877.8 3685 4941.9 4232.9 3583.2 5988.2 3350 FALSE TRUE FALSE 3018.911181 4398.325657 2349.150305 2865.892426 3641.058782 3916.894233 4351.663782 4675.701185 5331.309442 3466.412251 0.870903679 1.268840905 0.677689246 0.826760414 1.050382505 1.129956263 1.255379761 1.348858949 1.537990596 1 11.75922753 -5.003092449 1.572356906 0.937848789 1.331890748 0.094790239 0.23788612 0.266240672 1.188147723 0.020992848 0.103776213 9.93E-06 5.003092449 0.394041959 ATGDGSS(ph)PELPSLER ddPTM_HeLa_Curcumin_4h_R1 1 ATGDGSSPELPSLER 15 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 0 ATGDGS(0.011)S(0.989)PELPSLER 212.24 1.54E-10 40588000 4906.6 3968.9 3716.9 4259.7 4692 5128 3002.1 1313.6 4323.8 3458.6 TRUE FALSE FALSE 4518.237433 4311.954031 3854.651584 4242.07449 4636.050964 4064.394996 3086.330846 1714.110593 3849.489958 3578.786093 1.262505586 1.204864979 1.077083537 1.185338933 1.295425556 1.135690955 0.86239601 0.478964249 1.075641253 1 11.8052546 -4.419086095 2.202916889 1.146645622 0.41499672 0.858225207 0.085828686 0.160168018 1.115667872 0.016172644 0.199191549 3.81E-05 4.419086095 -0.731648902 down LADILS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 LADILSPR 8 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 0 LADILS(1)PR;LADILS(1)PR;LADILS(1)PR ;; 102.06 0.013846 69640000 17555.7 14859.2 16016.2 16753.5 16607.9 16381.4 9892.7 1842.6 18296.2 14656 TRUE FALSE FALSE 16166.14782 16143.56304 16609.77446 16684.17846 16409.86164 12983.71298 10170.26254 2404.400258 16289.15263 15165.29491 1.065996271 1.06450703 1.095249025 1.100155227 1.082066767 0.856146423 0.670627416 0.158546225 1.074107212 1 13.88848593 -4.416480814 1.459787846 1.046656473 1.18E-13 0.972448337 0.047175039 0.109997064 0.261399751 0.007704129 0.152584075 3.83E-05 4.416480814 -1.046656473 down KDGVCGPPPSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 KDGVCGPPPSKK 12 2 Q08J23-2;Q08J23;Q08J23-3;A0A140T9Z1 Q08J23-2 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 0 1 KDGVCGPPPSK(1)K 103.11 0.0013898 4383200 5427.2 4435 4454 4259.5 3772.9 5970.7 3570.1 4236.5 6210.2 5184.2 FALSE TRUE FALSE 4997.631393 4818.341638 4619.069158 4241.875318 3727.910632 4732.309516 3670.267398 5528.189348 5528.956597 5364.350564 0.931637732 0.898215279 0.861067729 0.790752817 0.69494165 0.882177527 0.684196037 1.030542147 1.030685174 1 12.38918781 -7.121862438 1.007363844 0.977543802 0.807698533 0.38180484 0.094245393 0.345469274 0.687869503 0.018013518 0.023003175 7.55E-08 7.121862438 -0.169845269 KDIDHETVVEEQIIGENS(ph)PPDYSEYMTGK ddPTM_HeLa_Curcumin_4h_R1 1 KDIDHETVVEEQIIGENSPPDYSEYMTGK 29 1 A0A494C032;H0YJU4;H0YJV7;P25490 A0A494C032 YY1 Transcriptional repressor protein YY1 1 0 KDIDHET(0.005)VVEEQIIGENS(0.955)PPDY(0.011)S(0.013)EY(0.012)MT(0.003)GK 51.586 0.0036318 16460000 728.92 611.16 603.62 717 907.45 927.18 971.9 774.64 1053.7 791.05 TRUE FALSE FALSE 671.2252128 663.9859471 625.9906882 714.033244 896.6292514 734.8724165 999.1688983 1010.82417 938.1117462 818.5389286 0.820028455 0.811184324 0.764765934 0.872326555 1.095402088 0.897785543 1.220673646 1.234912763 1.146080795 1 9.676907221 -4.682021656 1.13669089 0.89448854 1.321021796 0.460475902 0.123472863 0.488869395 0.804011528 0.016586075 0.20694576 2.08E-05 4.682021656 0.426533256 KDIET(ph)T(ph)TIS(ph)NFHTQ ddPTM_HeLa_Curcumin_4h_R1 1 KDIETTTISNFHTQ 14 1 A0A0C4DH79;Q5VWQ0-4 A0A0C4DH79 RSBN1 3 0 KDIET(0.89)T(0.975)T(0.191)IS(0.806)NFHT(0.138)Q 41.644 0.018834 6334400 5073.3 3936.3 4671.2 4514.4 3978.5 5974.1 5479.3 3416.3 5081.8 3667.2 TRUE FALSE FALSE 4671.742952 4276.536232 4844.318781 4495.720609 3931.058986 4735.004318 5633.034411 4457.914143 4524.339254 3794.634927 1.231144245 1.126995433 1.276623147 1.184757083 1.035951827 1.24781551 1.484473347 1.174793947 1.192298954 1 11.88974538 -13.52287875 0.174929587 0.060181758 1.284968944 0.076114036 0.122722954 44.72336567 0.504809734 14.36150636 0.164840058 3.00E-14 13.52287875 1.224787185 KDIEVLS(ph)EDTDYEEDEVTK ddPTM_HeLa_Curcumin_4h_R1 1 KDIEVLSEDTDYEEDEVTK 19 1 H7C5R6;Q4LE39-2;Q4LE39;H0Y7Y8;Q4LE39-4;Q4LE39-3 H7C5R6 ARID4B AT-rich interactive domain-containing protein 4B 1 0 KDIEVLS(0.933)EDT(0.067)DYEEDEVTK 71.002 0.0045265 2352200 1532 1101.4 914.29 1028.9 1199.1 1198.3 961.47 927.82 1539.8 1431.5 TRUE FALSE FALSE 1410.740583 1196.600108 948.1743917 1024.642684 1184.801516 949.7590724 988.4462605 1210.708047 1370.887792 1481.244518 0.952402231 0.807834286 0.640120102 0.691744457 0.799868962 0.641189932 0.667307962 0.817358668 0.925497293 1 10.5325941 -7.154008974 2.611584319 0.979817632 0.707928638 0.773003214 0.060100856 0.078762446 1.034506485 0.009796294 0.012078728 7.01E-08 7.154008974 -0.271888994 KDLYANTVLSGGTTMYPGIADR ddPTM_HeLa_Curcumin_4h_R1 2 KDLYANTVLSGGTTMYPGIADR 22 1 P60709;A0A2R8Y793;P63261 P60709;P63261 ACTB;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 0 0 ; ; 140.47 4.17E-05 97196000 8157.8 6331.7 7649 6679.3 6665.1 10986.2 8578.6 8375.3 8684.2 7510 FALSE FALSE TRUE 7512.101522 6878.983934 7932.478669 6651.662826 6585.623036 8707.53828 8819.292428 10928.89041 7731.564987 7770.971941 0.966687511 0.885215387 1.020783337 0.85596279 0.847464524 1.120521133 1.134902107 1.406373681 0.994928954 1 12.92387934 -4.36281777 1.388042531 0.963507261 1.525343816 0.797209363 0.071372792 0.355977163 0.690237081 0.01061462 0.26340563 4.34E-05 4.36281777 0.561836554 KDNDFIYHDR ddPTM_HeLa_Curcumin_4h_R1 2 KDNDFIYHDR 10 1 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 0 ; ; 96.229 0.0043706 38569000 27291 22829 25274 25978 26104 30245 23358 22787.8 27592 24935 FALSE FALSE TRUE 25130.88855 24802.23704 26210.67667 25870.50992 25792.72685 23971.84607 24013.36262 29735.69532 24565.22663 25801.48939 0.97400922 0.961271524 1.015859057 1.00267506 0.999660386 0.929087686 0.930696761 1.152479799 0.952085605 1 14.65516673 -4.250461639 24.99939474 0.982641185 1.152479897 0.754235476 0.030210569 633.8465681 1443420.292 0.004144458 0.083853175 5.62E-05 4.250461639 0.169838712 KDPELWGSVLLESNPYR ddPTM_HeLa_Curcumin_4h_R1 1 KDPELWGSVLLESNPYR 17 1 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 76.761 0.017675 12093000 1320.1 1320.8 1317.8 1385 1510.7 1916.1 1312.5 829 1273.8 1457.7 FALSE FALSE TRUE 1215.612692 1434.964067 1366.638827 1379.269237 1492.685889 1518.679261 1349.325218 1081.758284 1134.067327 1508.354966 0.805919508 0.951343748 0.906045896 0.914419528 0.98961181 1.006844738 0.894567424 0.717177526 0.751857058 1 10.55876027 -4.278332913 4.307936818 0.921748231 0.704762864 0.360165941 0.078451325 0.158589742 6.767691126 0.010903991 0.10174055 5.27E-05 4.278332913 -0.216985367 KDPSGASNPS(ph)ADSPLHR ddPTM_HeLa_Curcumin_4h_R1 1 KDPSGASNPSADSPLHR 17 1 P55317-2;P55317 P55317-2 FOXA1 Hepatocyte nuclear factor 3-alpha 1 0 KDPSGAS(0.001)NPS(0.825)ADS(0.174)PLHR 93.029 0.0016997 0 1192.1 1172.6 1095.8 1212.4 1096.3 1124.8 966.15 676.05 1225 1178.4 TRUE FALSE FALSE 1097.744027 1273.954319 1136.411312 1207.38341 1083.227339 891.5038009 993.2575687 882.1745328 1090.620565 1219.349312 0.900270346 1.044782087 0.931981755 0.990186649 0.888365071 0.731130769 0.814580005 0.723479748 0.894428326 1 10.25189576 -5.445786676 3.598634131 0.959813893 0.762924324 0.774506953 0.049029219 0.085875805 2.121014848 0.007211783 0.016764781 3.58E-06 5.445786676 -0.19688957 KDS(ph)EEEVSLLGSQDIEEGNHQVEDGCR ddPTM_HeLa_Curcumin_4h_R1 1 KDSEEEVSLLGSQDIEEGNHQVEDGCR 27 1 Q9Y487 Q9Y487 ATP6V0A2 V-type proton ATPase 116 kDa subunit a isoform 2 1 0 KDS(0.991)EEEVS(0.008)LLGS(0.001)QDIEEGNHQVEDGCR 67.788 0.00049648 11310000 1339.2 1413 1211.1 1526.3 1097.3 1006.2 994.23 663.14 1670.4 1528.7 TRUE FALSE FALSE 1233.200907 1535.133424 1255.984431 1519.984575 1084.215414 797.5027778 1022.125418 865.3283333 1487.161299 1581.822211 0.779607783 0.970484175 0.794011124 0.960907341 0.685421792 0.504167138 0.646169595 0.547045254 0.940157047 1 10.62737174 -5.596832768 4.277592411 0.894916888 0.575612001 0.805250221 0.076485552 0.085637158 3.031323531 0.013642554 0.028372827 2.53E-06 5.596832768 -0.319304887 KDS(ph)EGYSESPDLEFEYADTDK ddPTM_HeLa_Curcumin_4h_R1 1 KDSEGYSESPDLEFEYADTDK 21 1 Q5VSL9;Q5VSL9-4 Q5VSL9 STRIP1 Striatin-interacting protein 1 1 0 KDS(0.817)EGY(0.177)S(0.004)ES(0.001)PDLEFEYADTDK 94.707 0.00015562 7503200 1825 1475 1589.6 1386.9 1625.9 1658.4 1305.7 1176.5 1179.1 1341.9 TRUE FALSE FALSE 1680.549324 1602.492428 1648.511974 1381.161375 1606.512204 1314.429146 1342.334428 1535.209434 1049.75568 1388.530925 1.210307451 1.154091996 1.187234612 0.994692556 1.156986982 0.946632965 0.966729947 1.105635752 0.756018941 1 10.43934359 -5.263574113 24.96871209 1.107703302 1.002372595 0 0.135840916 233.4796375 2730898.411 0.013794088 0.032341028 5.45E-06 5.263574113 -0.105330708 KDS(ph)ISEDEMVLR ddPTM_HeLa_Curcumin_4h_R1 1 KDSISEDEMVLR 12 1 Q8N5D0-5;Q8N5D0-3;Q8N5D0-6;Q8N5D0-2;Q8N5D0-4;Q8N5D0 Q8N5D0-5 WDTC1 WD and tetratricopeptide repeats protein 1 1 0 KDS(0.958)IS(0.042)EDEMVLR 69.045 0.017987 21201000 2707.9 2239.4 2545.1 2676 2727.3 3221.2 2291.2 2331 2702.9 2801.3 TRUE FALSE FALSE 2493.566858 2432.963757 2639.423645 2664.927421 2694.778729 2553.08681 2355.484906 3041.711169 2406.398632 2898.644966 0.860252596 0.839345206 0.910571552 0.919370068 0.929668435 0.880786312 0.812615871 1.049356235 0.830180536 1 11.50116292 -9.394840579 1.130418543 0.99976795 0.893798243 0 0.080220288 0.472702762 1.084188357 0.039016283 0.010056415 4.03E-10 9.394840579 -0.105969706 KDS(ph)SSEVFSDAAK ddPTM_HeLa_Curcumin_4h_R1 1 KDSSSEVFSDAAK 13 1 Q5T5U3;E7ESW5;A0A1B0GV73;Q5T5U3-3;A0A1B0GTZ9 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 0 KDS(0.604)S(0.145)S(0.058)EVFS(0.193)DAAK 100.77 0.010469 7876500 1539.7 1448.8 1608 1333.8 1960.5 2013 1953 811.14 1673.2 1792.5 TRUE FALSE FALSE 1417.83112 1574.027816 1667.593895 1328.281089 1937.122318 1595.481109 2007.795924 1058.452852 1489.654146 1854.789242 0.764416295 0.848628934 0.8990746 0.71613586 1.044389451 0.860195365 1.082492759 0.570659366 0.803139307 1 10.85703955 -9.564024117 1.354586385 0.99958359 0.84788036 0 0.152806739 0.660197692 2.180529781 0.090524122 0.021540057 2.73E-10 9.564024117 -0.151703231 SES(ph)LTAESR ddPTM_HeLa_Curcumin_4h_R1 2 SESLTAESR 9 0 Q15751;H0YNB1 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 0 S(0.049)ES(0.902)LT(0.049)AESR;S(0.017)ES(0.943)LT(0.04)AESR ; 109.16 0.0094225 34557000 3529.6 2534.5 3623.3 4170.9 3154 4927.6 4195.7 15556.9 2966.1 3255.7 TRUE FALSE FALSE 3250.228436 2753.570886 3757.582685 4153.641921 3116.39061 3905.560215 4313.42005 20300.12719 2640.726251 3368.835333 0.964792908 0.81736583 1.115395178 1.232960804 0.925064689 1.159320605 1.280389103 6.025859144 0.783869198 1 11.7180342 -4.259416343 4.611163765 1.009080424 6.346247264 0.992018034 0.134617293 0.010131144 0.566587757 0.016782942 0.174438996 5.50E-05 4.259416343 5.33716684 up KDSGSSSVSSTSSSSSS(ph)SPGDK ddPTM_HeLa_Curcumin_4h_R1 1 KDSGSSSVSSTSSSSSSSPGDK 22 1 Q9H7S9 Q9H7S9 ZNF703 Zinc finger protein 703 1 0 KDSGSSSVSST(0.015)S(0.015)S(0.093)S(0.093)S(0.055)S(0.036)S(0.637)S(0.055)PGDK 106.06 1.97E-05 6602900 2854.3 2372.1 2378 2739 2997.1 3472.8 2363.7 1521.4 2913.9 2350.7 TRUE FALSE FALSE 2628.379143 2577.133754 2466.130772 2727.666744 2961.36154 2752.502133 2430.01906 1985.267856 2594.25246 2432.38665 1.080576208 1.059508263 1.013872845 1.121395212 1.217471548 1.131605509 0.999026639 0.816181036 1.066546086 1 11.24815686 -4.321954554 3.323807654 1.062447482 0.798131834 0.614363122 0.062770902 0.172228972 3.106013134 0.010262593 0.105034907 4.76E-05 4.321954554 -0.264315649 KDTDDIESPK ddPTM_HeLa_Curcumin_4h_R1 1 KDTDDIESPK 10 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;Q9UPQ0-2;G5EA03;Q9UPQ0-5;Q9UPQ0-4;D6RD46;D6RJ93;D6R8Y0;Q9UPQ0-7;D6RGH8 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 0 0 102.07 0.013953 2960900 1058.1 873.65 959.72 1077.4 1232.1 1736.6 1049.2 1014.4 1150.4 697.68 FALSE FALSE TRUE 974.3502685 949.1644131 995.2880675 1072.942004 1217.408012 1376.409584 1078.637728 1323.68589 1024.203998 721.9243281 1.349657063 1.314769951 1.378659825 1.486225027 1.686337425 1.906584293 1.494114669 1.833552131 1.418713788 1 9.495703812 -6.372419168 0.166004133 0.782078798 2.187801024 0.533855033 0.172457314 2.006601744 0.166754608 0.441608007 0.865509576 4.24E-07 6.372419168 1.405722226 LQSIGT(ph)ENTEENR ddPTM_HeLa_Curcumin_4h_R1 1 LQSIGTENTEENR 13 0 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 0 LQS(0.02)IGT(0.927)ENT(0.053)EENR 236.12 8.80E-20 19103000 1054.8 836.48 729.41 853.91 828.17 998.58 877.79 1555.7 733.08 601.4 TRUE FALSE FALSE 971.311467 908.7816039 756.4425763 850.3767467 818.2946136 791.4632517 902.4184249 2030.025768 652.6629581 622.2986052 1.560844679 1.460362592 1.215562063 1.366509164 1.314954922 1.271838383 1.450137309 3.262140958 1.048793863 1 9.281463202 -4.259346328 4.060641168 1.293089362 3.436824937 0.931276317 0.160561911 0.054569723 1.90399143 0.029296316 0.342622221 5.50E-05 4.259346328 2.143735574 up KDYPAAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 KDYPAAKR 8 2 H0YBT0;A0A087WUS5;P01106;P01106-2;A0A494C1T8 H0YBT0 MYC Myc proto-oncogene protein 0 1 KDYPAAK(1)R 74.92 0.014196 2326600 1840.6 844.02 1514.2 1062.3 1390 1996.4 1363.4 307.69 1394.3 1469.2 FALSE TRUE FALSE 1694.914568 916.9733279 1570.317584 1057.904484 1373.425158 1582.324136 1401.653335 401.5032646 1241.348778 1520.254591 1.114888637 0.603170899 1.032930664 0.695873238 0.903417866 1.040828389 0.921985925 0.264102649 0.816540062 1 10.57009723 -4.262911017 4.153817289 0.984563423 0.205967525 0.521441013 0.169242473 0.112956189 4.289123775 0.023605811 0.260784001 5.46E-05 4.262911017 -0.778595898 KEDGTFYEFGEDIPEAPER ddPTM_HeLa_Curcumin_4h_R1 2 KEDGTFYEFGEDIPEAPER 19 1 O43776 O43776 NARS "Asparagine--tRNA ligase, cytoplasmic" 0 0 ; ; 143.33 0.0002418 33758000 6255.1 4975.5 5848.3 5346.2 5734.7 5914.8 4753.7 5019.1 5508.6 4763.3 FALSE FALSE TRUE 5760.002235 5405.56005 6065.043143 5324.078841 5666.317448 4688.003806 4887.076028 6549.400485 4904.320362 4928.82432 1.168636141 1.096724025 1.230525324 1.080192455 1.149628609 0.951140374 0.991529767 1.328795684 0.995028437 1 12.26702784 -9.457361949 1.184766279 0.999815257 1.121482592 0.193880803 0.103114747 0.70547353 1.766990574 0.070062329 0.017240756 3.49E-10 9.457361949 0.121667335 KEDLYLK(ac)PIQR ddPTM_HeLa_Curcumin_4h_R1 1 KEDLYLKPIQR 11 2 P13639 P13639 EEF2 Elongation factor 2 0 1 KEDLYLK(1)PIQR 72.29 0.016311 12671000 1587.4 2302 1856.1 1683.2 3140.4 3631 2724.6 2838 3558.1 2183.7 FALSE TRUE FALSE 1461.755615 2500.974622 1924.888699 1676.235364 3102.952781 2877.88967 2801.044943 3703.293135 3167.785332 2259.583412 0.646913766 1.106829962 0.85187769 0.741833807 1.373241087 1.273637279 1.239628919 1.638927386 1.401933345 1 11.1418411 -5.754850173 24.96474147 0.848016241 1.36354085 0.393488803 0.234095781 70.65113026 267675.6485 0.025963916 0.0509733 1.76E-06 5.754850173 0.515524609 KEEASS(ph)PGAGEGPAEEGTR ddPTM_HeLa_Curcumin_4h_R1 1 KEEASSPGAGEGPAEEGTR 19 1 J3KPS2;A0A494C1T9;Q6ZRV2 J3KPS2 FAM83H Protein FAM83H 1 0 KEEAS(0.037)S(0.963)PGAGEGPAEEGTR 55.827 0.013808 13297000 1460.1 1247.4 1416.1 1376.7 1658.7 2798.4 3063.4 1268.9 1697.1 1464.1 TRUE FALSE FALSE 1344.531544 1355.219698 1468.581912 1371.00358 1638.921086 2217.980296 3149.350759 1655.781769 1510.932376 1514.977366 0.887492826 0.894547818 0.96937548 0.904966378 1.081812258 1.464035269 2.078810436 1.092941588 0.99733 1 10.56508052 -5.269596835 3.097294772 0.942700423 1.620139912 0.587111852 0.226287994 0.109054827 2.132306618 0.028669466 0.076023394 5.38E-06 5.269596835 0.677439488 KEEELQAALAR ddPTM_HeLa_Curcumin_4h_R1 2 KEEELQAALAR 11 1 P35579;Q7Z406-5;Q7Z406-4;P35749-4;P35749-3;P35749;P35749-2;Q7Z406;Q7Z406-6;Q7Z406-2;A0A0C4DFM8 P35579;P35749-4;Q7Z406 MYH9;MYH14;MYH11 Myosin-9;Myosin-14;Myosin-11 0 0 ; ; 98.156 0.0035466 15142100 10241 8700.1 10890.5 9651.6 12072.3 13337.2 10638.5 9814.5 9398 9393.4 FALSE FALSE TRUE 9430.414044 9452.097877 11294.11151 9611.664237 11928.34571 10570.91438 10936.98768 12806.89587 8367.062913 9719.819951 0.970225178 0.972456067 1.161967152 0.988872663 1.227218793 1.087562777 1.125225337 1.317606286 0.860824887 1 13.24671387 -1 0.27750189 0.975032403 3.258844185 0.614180695 0.081588635 21.92072615 0.279063854 0.030284806 24.52438083 0.1 1 2.283811782 KEEENADS(ph)DDEGELQDLLSQDWR ddPTM_HeLa_Curcumin_4h_R1 4 KEEENADSDDEGELQDLLSQDWR 23 1 J3QQQ3;Q96NB3 J3QQQ3 ZNF830 Zinc finger protein 830 1 0 KEEENADS(1)DDEGELQDLLSQDWR;KEEENADS(1)DDEGELQDLLSQDWR;KEEENADS(1)DDEGELQDLLSQDWR;KEEENADS(1)DDEGELQDLLSQDWR ;;; 129.2 3.46E-06 79593700 6334.73 5510.38 5724.27 6168.72 5499.3 7818.75 5691.85 5052.77 6402.71 5498.26 TRUE FALSE FALSE 5833.329436 5986.672693 5936.416482 6143.195471 5433.724439 6197.053115 5851.547992 6593.336313 5700.348732 5689.324126 1.025311497 1.052264304 1.04343088 1.079775969 0.955073805 1.089242409 1.028513733 1.158896236 1.001937771 1 12.47404156 -1.000002152 0.942071058 1.020315328 90.30319895 0.490981366 0.038285152 648.766004 1.120920191 0.005557655 124809.4239 0.099999504 1.000002152 89.28288362 KEELTLEGIR ddPTM_HeLa_Curcumin_4h_R1 2 KEELTLEGIR 10 1 P60842;J3KT12;P60842-2;J3KSZ0;J3KTB5;J3QS69;J3KTN0 P60842 EIF4A1 Eukaryotic initiation factor 4A-I 0 0 ; ; 95.483 0.0044341 10191800 9730.2 9129.1 9520.5 9447.3 9688.2 9363.5 8785.8 8387.5 9623.5 9232.2 FALSE FALSE TRUE 8960.044403 9918.178726 9873.338105 9408.209576 9572.674543 7421.404552 9032.305902 10944.81014 8567.826127 9553.018263 0.937928114 1.038224617 1.033530747 0.984841577 1.002057599 0.776864897 0.945492373 1.145691324 0.896871114 1 13.22174091 -4.256968177 24.34207957 0.967687681 1.145691426 0.361763157 0.073916838 276.2298329 1503766.391 0.009914635 0.103772257 5.53E-05 4.256968177 0.178003745 KEEPEPETEAVSS(ph)SQEIPTMPQPIEK ddPTM_HeLa_Curcumin_4h_R1 1 KEEPEPETEAVSSSQEIPTMPQPIEK 26 1 A0A0A0MRY2;B0QZE2;B7Z2J6;E7ENI9;J3QKD2;Q15326-4;Q15326-5;Q15326-2;Q15326-6;Q15326-3;Q15326 A0A0A0MRY2 ZMYND11 Zinc finger MYND domain-containing protein 11 1 0 KEEPEPETEAVS(0.013)S(0.473)S(0.348)QEIPT(0.166)MPQPIEK 82.639 5.33E-05 14214000 3724.6 2637.1 2729.5 3345.9 3177.9 3871.1 4253.3 3078.9 4031.5 3248.5 TRUE FALSE FALSE 3429.79398 2865.039173 2830.657671 3332.055552 3140.005618 3068.190224 4372.636151 4017.642436 3589.254536 3361.385133 1.020351386 0.85233886 0.842110487 0.991274555 0.93414039 0.912775568 1.300843544 1.19523419 1.067790329 1 11.71484013 -4.760277605 24.99999999 0.974716224 1.248038932 0.71061398 0.074349905 12.75434307 274421.4461 0.01084391 0.03650401 1.74E-05 4.760277605 0.273322709 KEEPS(ph)QNDISPK ddPTM_HeLa_Curcumin_4h_R1 1 KEEPSQNDISPK 12 1 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 0 KEEPS(0.994)QNDIS(0.006)PK 113.54 0.0071312 34567000 3909.4 3374.7 3866.6 4254.6 3868.7 4553.4 3169.4 2548.6 5217.5 3911.8 TRUE FALSE FALSE 3599.966865 3666.394031 4009.899597 4236.995593 3822.568279 3608.973513 3258.324834 3325.656408 4645.153304 4047.734759 0.889378153 0.905789102 0.990652757 1.046757222 0.944372225 0.891603261 0.804974888 0.821609272 1.147593303 1 11.98289904 -4.981670286 2.671262029 0.954002133 0.812207998 0.42877272 0.075131448 0.170346425 2.419275291 0.008015605 0.028405549 1.04E-05 4.981670286 -0.141794135 KEEPSQNDIS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 KEEPSQNDISPK 12 1 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 0 KEEPSQNDIS(1)PK 178.67 0.0001834 6143200 2657.5 2279.6 2665 3290.3 2583.9 2997.2 2543.1 1865.9 3445.1 3013.8 TRUE FALSE FALSE 2447.156071 2476.638466 2763.767244 3276.68561 2553.08868 2375.546935 2614.452542 2434.80432 3067.181149 3118.529326 0.784714785 0.794168728 0.886240582 1.050715022 0.818683557 0.761752315 0.838360736 0.780754024 0.98353449 1 11.60665011 -9.417350277 1.115856027 1.001048136 0.838248359 0.373319735 0.078787178 0.468456383 1.032752004 0.059787353 0.014716712 3.83E-10 9.417350277 -0.162799777 KEES(ph)DEEETASK ddPTM_HeLa_Curcumin_4h_R1 3 KEESDEEETASK 12 1 Q9BY89;Q9BY89-2;A0A1B0GVJ7 Q9BY89;A0A1B0GVJ7 KIAA1671 Uncharacterized protein KIAA1671 1 0 KEES(0.999)DEEET(0.001)ASK;KEES(0.992)DEEET(0.008)AS(0.001)K;KEES(1)DEEETASK ;; 107.73 0.0029308 248090000 12483.6 16611.6 14122.9 11635.7 13453.3 12575.8 9280.7 5734.7 10324.1 11690.4 TRUE FALSE FALSE 11495.50989 18047.43268 14646.3071 11587.55456 13292.87818 9967.437322 9541.091464 7483.183631 9191.57206 12096.64053 0.950305984 1.491937587 1.210774765 0.957915095 1.098890072 0.823983923 0.788738943 0.618616682 0.75984502 1 13.56231882 -4.863571767 1.596632723 1.039908519 0.645896726 0.394067777 0.185885041 0.374175337 1.667873727 0.026535649 0.160406889 1.37E-05 4.863571767 -0.394011793 KEES(ph)DEEETASKAER ddPTM_HeLa_Curcumin_4h_R1 2 KEESDEEETASKAER 15 2 Q9BY89;Q9BY89-2;A0A1B0GVJ7 Q9BY89;A0A1B0GVJ7 KIAA1671 Uncharacterized protein KIAA1671 1 0 KEES(0.999)DEEET(0.001)ASKAER;KEES(1)DEEETASKAER ; 98.077 0.0026742 34874000 5416 4612.3 3961.5 4860.1 4140.2 5390.5 4207.7 3560 6178.3 6292.7 TRUE FALSE FALSE 4987.317885 5010.96666 4108.316675 4839.990194 4090.830819 4272.449537 4325.756738 4645.427612 5500.555947 6511.370857 0.765939768 0.769571688 0.630944968 0.743313551 0.628259534 0.656152081 0.664338867 0.713433118 0.844761582 1 12.66874559 -8.651259856 0.396964458 1.052146839 0.65684086 0.68377573 0.061071379 0.315231995 0.092915727 0.052474835 0.01554946 2.23E-09 8.651259856 -0.39530598 KEESDEEET(ph)ASK ddPTM_HeLa_Curcumin_4h_R1 2 KEESDEEETASK 12 1 Q9BY89;Q9BY89-2;A0A1B0GVJ7 Q9BY89;A0A1B0GVJ7 KIAA1671 Uncharacterized protein KIAA1671 1 0 KEES(0.36)DEEET(0.638)AS(0.002)K;KEES(0.028)DEEET(0.972)ASK ; 211.83 7.99E-09 92511000 12687.1 14814.1 13777.3 10954 12579.9 13040.8 9515.4 6791.2 10159.9 11368.5 TRUE FALSE FALSE 11682.90265 16094.56479 14287.89886 10908.67525 12429.89291 10335.99108 9782.376515 8861.805617 9045.384389 11763.55453 0.993143919 1.368171904 1.214590269 0.927328149 1.056644306 0.87864523 0.831583387 0.753327202 0.768932925 1 13.52203644 -4.993230221 1.577685989 1.042097931 0.766739208 0.326431398 0.152032549 0.37369139 1.677704026 0.020522411 0.102556606 1.02E-05 4.993230221 -0.275358722 KEESEES(ph)DDDMGFGLFD ddPTM_HeLa_Curcumin_4h_R1 3 KEESEESDDDMGFGLFD 17 1 P05387;H0YDD8;P05386-2;P05386 P05387 RPLP2;RPLP1 60S acidic ribosomal protein P2;60S acidic ribosomal protein P1 1 0 KEES(0.052)EES(0.948)DDDMGFGLFD;KEES(0.178)EES(0.822)DDDMGFGLFD;KEES(0.018)EES(0.982)DDDMGFGLFD ;; 74.428 0.0060281 132821900 16053.41 13362.03 13525.65 14070.84 14405.75 16255 12541 16398.54 15022.15 13358.26 TRUE FALSE FALSE 14782.76566 14516.98433 14026.92249 14012.61859 14233.97084 12883.52977 12892.86671 21398.37936 13374.25773 13822.45854 1.069474408 1.050246184 1.014792155 1.013757325 1.029771281 0.932072231 0.932747721 1.548087794 0.967574451 1 13.75472662 -4.255630832 24.99969043 1.020188985 1.548088022 0.923339569 0.046990681 134.1894705 577527.7506 0.006946743 0.083487431 5.55E-05 4.255630832 0.527899037 KEEST(ph)T(ph)GNANLLEK ddPTM_HeLa_Curcumin_4h_R1 1 KEESTTGNANLLEK 14 1 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101;F5GWN9;F5H7D5;F5H797;F5H8B8;F5H692;A0A0A0MSJ1 Q76FK4-2 NOL8 Nucleolar protein 8 2 0 KEES(0.408)T(0.601)T(0.991)GNANLLEK 63.76 0.01572 19011000 1534.9 1086.7 1250.5 1468.2 1665.2 1337.9 1048.5 896.42 1654.9 1295.3 TRUE FALSE FALSE 1413.411045 1180.629506 1296.84463 1462.124977 1645.343578 1060.404459 1077.918088 1169.734331 1473.36161 1340.311579 1.054539159 0.880861976 0.967569519 1.090884389 1.227582902 0.791162649 0.804229483 0.872733139 1.099267987 1 10.3883527 -5.22060377 24.9980672 1.027340748 0.820860442 0.561763867 0.089260017 302.4756259 185164.0745 0.012344605 0.031472401 6.02E-06 5.22060377 -0.206480306 KEFS(ph)PFGTITSAK ddPTM_HeLa_Curcumin_4h_R1 1 KEFSPFGTITSAK 13 1 P11940;P11940-2;E7EQV3;A0A087WTT1;E7ERJ7;H0YAR2;H0YAP2;H0YB86 P11940 PABPC1 Polyadenylate-binding protein 1;Polyadenylate-binding protein 1 0 KEFS(0.968)PFGT(0.031)IT(0.001)SAK 96.673 0.01378 12763000 1747.2 1569.3 1151.8 1321.8 1264.7 2479.1 1567.2 1220.1 1531 1557.3 TRUE FALSE FALSE 1608.907276 1704.943299 1194.486721 1316.330742 1249.619279 1964.906715 1611.171414 1592.102873 1363.05313 1611.416059 0.998443119 1.058040405 0.741265246 0.816878257 0.775478978 1.219366472 0.99984818 0.988014774 0.845872872 1 10.65411332 -4.753683598 0.006635371 1.908064133 6.45E-07 0 0.145026393 57001.78703 70.6343746 9755.581733 10567.41919 1.76E-05 4.753683598 -1.908063487 KEFSPFGTITSAK ddPTM_HeLa_Curcumin_4h_R1 2 KEFSPFGTITSAK 13 1 P11940;P11940-2;E7EQV3;A0A087WTT1;E7ERJ7;H0YAR2;H0YAP2;H0YB86 P11940 PABPC1 Polyadenylate-binding protein 1;Polyadenylate-binding protein 0 0 ; ; 143.93 0.00012222 5481900 5509.5 4578.3 5072.3 4964.9 4499.8 7579.7 5468.6 5241.5 5528.6 5030.1 FALSE FALSE TRUE 5073.417261 4974.027851 5260.2839 4944.356559 4446.142824 6007.584779 5622.034198 6839.609221 4922.126412 5204.895601 0.974739486 0.955644115 1.010641577 0.949943465 0.854223248 1.154218113 1.080143509 1.314072317 0.945672457 1 12.34565351 -4.202885317 1.13530047 0.978977166 1.488397553 0.731027191 0.06405566 0.690820046 0.656416045 0.008933615 0.4309549 6.27E-05 4.202885317 0.509420387 KEKPELSEPSHLNGPS(ph)SDPEAAFLSR ddPTM_HeLa_Curcumin_4h_R1 1 KEKPELSEPSHLNGPSSDPEAAFLSR 26 2 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 0 KEKPELSEPSHLNGPS(0.834)S(0.166)DPEAAFLSR 115.72 3.58E-09 71285000 2019.6 1669.6 1490.9 1271.8 2106 3133.9 1817.7 910.27 2298.5 1595.2 TRUE FALSE FALSE 1859.746529 1813.912784 1546.154066 1266.537629 2080.887325 2483.893814 1868.69977 1187.807133 2046.360301 1650.633081 1.126686815 1.098919442 0.93670367 0.767304159 1.260660136 1.504812815 1.13211094 0.719607008 1.239742693 1 10.68880374 KEKPELSEPSHLNGPSS(ph)DPEAAFLSR ddPTM_HeLa_Curcumin_4h_R1 1 KEKPELSEPSHLNGPSSDPEAAFLSR 26 2 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 0 KEKPELSEPSHLNGPS(0.265)S(0.735)DPEAAFLSR 130.62 1.44E-08 89602000 3564.1 2557.4 2379.8 2905.1 3550.9 4884 2711.1 1572.1 3653 2351.4 TRUE FALSE FALSE 3281.997724 2778.45026 2467.997481 2893.079466 3508.557837 3871.003346 2787.166169 2051.426053 3252.275039 2433.110975 1.34888945 1.141933224 1.014338231 1.189045422 1.442004854 1.590968676 1.145515432 0.843128848 1.336673531 1 11.24858641 -5.983665209 24.63467666 1.154220448 1.277024243 0.030972308 0.211193417 507.905837 765972.6548 0.033893253 0.061425108 1.04E-06 5.983665209 0.122803795 KELQAEATVSGS(ph)PEAPGTNVVSEPR ddPTM_HeLa_Curcumin_4h_R1 4 KELQAEATVSGSPEAPGTNVVSEPR 25 1 K7EJ02;Q9BZV1-2;Q9BZV1 K7EJ02 UBXN6 UBX domain-containing protein 6 1 0 KELQAEAT(0.002)VS(0.098)GS(0.9)PEAPGTNVVSEPR;KELQAEATVS(0.278)GS(0.722)PEAPGT(0.001)NVVSEPR;KELQAEATVS(0.204)GS(0.796)PEAPGTNVVSEPR;KELQAEAT(0.008)VS(0.114)GS(0.877)PEAPGTNVVSEPR ;;; 116.19 9.35E-09 33506500 9526.4 7678.9 8760.8 9002.5 10429 14434.1 9126.7 4699.35 10219.4 8629.1 TRUE FALSE FALSE 8772.375388 8342.629899 9085.482955 8965.25004 10304.64099 11440.30495 9382.770639 6132.160182 9098.357388 8928.960583 0.982463223 0.934333826 1.017529742 1.004064242 1.15406949 1.281258311 1.050824511 0.686772007 1.018971615 1 13.12427653 -5.975893251 24.63758477 0.989040341 1.063061864 0.022423055 0.14230235 490.1850104 500975.5173 0.020710318 0.037539292 1.06E-06 5.975893251 0.074021523 KELS(ph)PAGSISK ddPTM_HeLa_Curcumin_4h_R1 1 KELSPAGSISK 11 1 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 0 KELS(1)PAGSISK 167.22 0.00040633 41660000 2093.5 1839 1550.1 1848.1 1764 1971.4 1035.7 1130.4 2040.6 1643 TRUE FALSE FALSE 1927.797266 1997.954966 1607.54807 1840.453052 1742.965452 1562.509418 1064.758955 1475.053756 1816.751285 1700.094128 1.133935607 1.175202557 0.945564156 1.082559502 1.02521703 0.919072299 0.626294119 0.86763064 1.068618058 1 10.73139891 -5.053130306 2.972129285 1.063633162 0.747146511 0.691850132 0.083276995 0.106308598 1.846687848 0.012215789 0.038569877 8.85E-06 5.053130306 -0.316486651 KELSDIAHR ddPTM_HeLa_Curcumin_4h_R1 1 KELSDIAHR 9 1 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 59.757 0.017112 12149000 9037.6 7707.9 7695.9 7795.2 9733.4 11624 8679.4 8114 10912 8811.7 FALSE FALSE TRUE 8322.264424 8374.13653 7981.116824 7762.945528 9617.335562 9213.051371 8922.920605 10587.92125 9714.9809 9117.905919 0.912738571 0.918427609 0.875323445 0.85139566 1.054774599 1.010435011 0.978615121 1.16122291 1.065483784 1 13.15448681 -1.00001143 0.804544979 0.946420467 54.6194314 0.434528925 0.068425642 326.886488 1.050437525 0.01022536 32012.79571 0.099997368 1.00001143 53.67301093 KEMEMLWNK ddPTM_HeLa_Curcumin_4h_R1 1 KEMEMLWNK 9 1 A0A1B0GTP3;A0A1B0GW51;A0A1B0GV15;A0A1B0GWI1;A0A286YEX8;A0A286YFE0;A0A1B0GTZ2 A0A1B0GTP3 0 0 34.387 0.018805 6796500 3885 3042.8 2310 2085.2 7005 11235 5173.1 3633.4 5023.1 2892.7 FALSE FALSE TRUE 3577.498151 3305.806074 2395.610632 2076.571995 6921.46995 8904.734355 5318.243263 4741.206934 4472.078497 2993.22111 1.195200094 1.104430963 0.800345362 0.693758302 2.312381778 2.97496711 1.776762581 1.583981524 1.494068875 1 11.54748314 -5.754292498 24.99997726 1.046124613 2.192572266 0.652729207 0.397838103 73.82798758 258249.8562 0.055769581 0.109692165 1.76E-06 5.754292498 1.146447652 KEMEPIS(ph)HS(ph)S(ph)CLSTEGMEEK ddPTM_HeLa_Curcumin_4h_R1 1 KEMEPISHSSCLSTEGMEEK 20 1 C9JY48;Q86XK7-2 C9JY48 VSIG1 3 0 KEMEPIS(0.988)HS(0.916)S(0.916)CLS(0.107)T(0.072)EGMEEK 48.288 0.0081409 0 443.1 495.14 325.76 532.42 291.24 743.44 299.63 320.23 515.79 470.81 TRUE FALSE FALSE 408.0281674 537.9376953 337.8329522 530.2169871 287.7671532 589.2421637 308.0368114 417.8666528 459.2091274 487.1706125 0.837546759 1.104208016 0.693459218 1.088359958 0.590690706 1.209519106 0.632297605 0.857741913 0.942604327 1 8.928283298 -13.52287875 0.223630036 1.679336964 0.85076044 0.039232792 0.196108468 108.8526189 1.387729625 32.63824457 0.135930592 3.00E-14 13.52287875 -0.828576525 KEMQPTHPIR ddPTM_HeLa_Curcumin_4h_R1 6 KEMQPTHPIR 10 1 P27348;P31946-2;P31946;P63104;E7EX29;B0AZS6;P63104-2;B7Z2E6;H0YB80 P27348;P31946-2;P63104 YWHAQ;YWHAB;YWHAZ "14-3-3 protein theta;14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed;14-3-3 protein zeta/delta" 0 0 ;;;;; ;;;;; 90.827 0.0047318 17270810 19313.17 18058.04 18391.36 18439.56 19422.39 19644.64 16764.51 16808.93 20271 19370.59 FALSE FALSE TRUE 17784.51222 19618.89651 19072.95998 18363.26199 19190.79068 15570.12022 17234.87703 21933.89538 18047.32202 20043.71656 0.887286156 0.978805326 0.951568035 0.91616053 0.95744672 0.776808042 0.859864336 1.094302811 0.900397986 1 14.29086242 KENPLQFK ddPTM_HeLa_Curcumin_4h_R1 2 KENPLQFK 8 1 E7EQR4;P15311;E9PQ82;E9PNV3;A0A2R8Y5P0;P35241-3 E7EQR4 EZR;RDX Ezrin 0 0 ; ; 80.219 0.012264 6882900 7576.2 5578.8 6969.1 6635.6 7647.5 9823.8 7261.6 7280.1 8366.1 6633.3 FALSE FALSE TRUE 6976.535776 6061.006613 7227.380977 6608.143645 7556.308557 7786.233143 7465.340952 9499.768977 7448.359761 6863.806681 1.016423699 0.883038654 1.052969775 0.962752005 1.100891809 1.134389925 1.08763858 1.384037957 1.085164561 1 12.7447932 -1 0.634430382 0.999961774 30.15964412 0.742794389 0.063904089 58.08205895 0.367701089 0.009336039 2375.534073 0.1 1 29.15968234 KEPAITSQNS(ph)PEAR ddPTM_HeLa_Curcumin_4h_R1 1 KEPAITSQNSPEAR 14 1 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193;E5RIS7 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 1 0 KEPAITS(0.004)QNS(0.996)PEAR 147.75 0.00089777 9073400 2464.6 2147.4 2241.7 2746.4 2289.2 2920.9 1884.6 1806.4 2752.9 1905.7 TRUE FALSE FALSE 2269.524309 2333.011687 2324.779374 2735.036125 2261.902785 2315.072415 1937.476804 2357.163044 2450.913757 1971.922933 1.150919375 1.183115044 1.17894028 1.386989359 1.147054353 1.174017694 0.982531706 1.195362661 1.242905448 1 10.94538745 -8.762211722 0.755727937 1.003794662 1.17588596 0 0.117339872 0.587751329 0.652094937 0.054393732 0.020553902 1.73E-09 8.762211722 0.172091298 KEPAVLELEGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 KEPAVLELEGKK 12 2 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 0 1 ; KEPAVLELEGK(1)K;KEPAVLELEGK(1)K 141.37 2.59E-05 9084600 8253.6 9574.2 7679 7751.1 12791.2 16883.4 13014 12360 17407.8 7900.2 FALSE TRUE FALSE 7600.318851 10401.75119 7963.590495 7719.028002 12638.67329 13381.59252 13379.13781 16128.5071 15498.20789 8174.731362 0.929733164 1.272427279 0.974171522 0.944254638 1.546065887 1.636945844 1.636645563 1.972970901 1.895867547 1 12.99695561 -5.648675578 3.174650516 0.98942942 1.726324231 0.334573288 0.314928803 0.061440691 1.229606203 0.019351968 0.041135186 2.25E-06 5.648675578 0.736894812 KEPPLTPVPLK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 KEPPLTPVPLKR 12 2 A0A087WU64;A6NMQ1;P09884 A0A087WU64 POLA1 DNA polymerase;DNA polymerase alpha catalytic subunit 0 1 KEPPLTPVPLK(1)R 111.79 8.32E-05 0 4615.1 5187.4 4336.1 4506.3 4050.3 6448.8 5793.7 4637.3 5446.6 5291.6 FALSE TRUE FALSE 4249.809965 5635.775741 4496.79968 4487.654125 4002.002818 5111.246187 5956.255629 6051.191422 4849.121607 5475.482706 0.776152568 1.029274686 0.821260868 0.819590594 0.730894979 0.933478647 1.087804665 1.105143007 0.885606232 1 12.41877044 -4.814522249 3.9968533 0.880197215 1.100971847 0.511649751 0.087955537 0.157429645 5.084410107 0.014989016 0.052718364 1.53E-05 4.814522249 0.220774632 KEPVVGGTLS(ph)PLALANK ddPTM_HeLa_Curcumin_4h_R1 2 KEPVVGGTLSPLALANK 17 1 J3KTM2;O15534-4;O15534;J3KRL7 J3KTM2 PER1 Period circadian protein homolog 1 1 0 KEPVVGGT(0.001)LS(0.999)PLALANK;KEPVVGGT(0.051)LS(0.949)PLALANK ; 120.25 0.00029712 65182000 7230.9 6294.3 7108.8 6851.4 7335.4 7853.3 5938.4 4957.1 7132 6526.5 TRUE FALSE FALSE 6658.566635 6838.351245 7372.258382 6823.050722 7247.930146 6224.437055 6105.015522 6468.49697 6349.637443 6753.295389 0.985972959 1.012594719 1.091653475 1.010329081 1.073243465 0.921688849 0.904005403 0.95782823 0.940228004 1 12.72137595 -5.227619606 24.46116225 1.008183708 0.925457245 0.470878177 0.042337415 323.1350974 233716.4596 0.005523942 0.014082144 5.92E-06 5.227619606 -0.082726463 KEQSEVSVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 KEQSEVSVSPR 11 1 Q7L4I2;E9PI52 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 0 KEQSEVS(0.027)VS(0.973)PR;KEQSEVSVS(1)PR ; 137.95 0.002607 31843000 3656.4 2763.2 3016.1 3787.3 3103.8 4148.2 3059.5 3031.4 3534 3009.8 TRUE FALSE FALSE 3366.992082 3002.038695 3127.879319 3771.629156 3066.789212 3287.81656 3145.341336 3955.659905 3146.329042 3114.390326 1.081107931 0.963925 1.004331183 1.211032903 0.984715752 1.055685452 1.009938064 1.27012336 1.010255206 1 11.60473405 -4.256935253 24.83119226 1.039475301 1.270123462 0.524939865 0.066823788 258.649621 1425875.518 0.00890569 0.095609028 5.53E-05 4.256935253 0.230648161 KES(ph)APQVLLPEEEK ddPTM_HeLa_Curcumin_4h_R1 1 KESAPQVLLPEEEK 14 1 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5 B1ALK7 ARHGEF7 Rho guanine nucleotide exchange factor 7 1 0 KES(1)APQVLLPEEEK 81.357 0.0083716 6522300 2961.9 2797.6 2697.5 2978.8 3436.2 4477.1 4236.6 1326.5 2986.3 2489.9 TRUE FALSE FALSE 2727.46249 3039.412078 2797.471723 2966.474515 3395.225559 3548.498993 4355.467594 1730.943744 2658.710361 2576.42384 1.058623371 1.179701892 1.085796397 1.151392278 1.317805521 1.377296289 1.690508963 0.671839671 1.031938271 1 11.33115423 -6.483858324 0.910081368 1.025416195 1.295675537 0.113202379 0.240083986 0.658463675 1.087991107 0.042727131 0.081161065 3.28E-07 6.483858324 0.270259342 EFGYDSPHDLDS(ph)D ddPTM_HeLa_Curcumin_4h_R1 1 EFGYDSPHDLDSD 13 0 Q96CW6 Q96CW6 SLC7A6OS Probable RNA polymerase II nuclear localization protein SLC7A6OS 1 0 EFGYDSPHDLDS(1)D 105.65 0.0049804 27275000 3863.8 4151.1 3154.6 3558.4 4021.6 5579.9 3972.5 12648 3222.7 2958.5 TRUE FALSE FALSE 3557.976153 4509.902587 3271.512251 3543.676284 3973.645047 4422.565842 4083.957659 16504.31698 2869.177873 3061.307655 1.162240635 1.473194822 1.068664969 1.157569471 1.298022118 1.444665594 1.334056593 5.391263746 0.93723931 1 11.57993232 -4.259250104 4.901464152 1.153830859 5.619395591 0.982165979 0.169119894 0.016609253 1.181828819 0.025299 0.251387873 5.50E-05 4.259250104 4.465564732 up KES(ph)PS(ph)ST(ph)GS(ph)S(ph)TWK ddPTM_HeLa_Curcumin_4h_R1 1 KESPSSTGSSTWK 13 1 C9JFM2;C9JXD6;C9JK00;Q6NV74 C9JFM2 KIAA1211L Uncharacterized protein KIAA1211-like 5 0 KES(0.983)PS(0.511)S(0.511)T(0.996)GS(0.697)S(0.697)T(0.606)WK 85.909 0.0041514 6711100 6209.4 5383.4 5754.2 5384.3 5709.3 6562.5 5673.8 5090.6 5999.3 5904.2 TRUE FALSE FALSE 5717.919438 5848.717108 5967.455714 5362.021193 5641.220326 5201.363525 5832.991558 6642.700506 5341.1918 6109.370511 0.93592612 0.957335473 0.976770963 0.877671633 0.923371781 0.851374707 0.954761468 1.087297045 0.874262216 1 12.57680802 -9.276306204 0.683561469 1.006589223 0.940014826 0 0.07141085 1.700517473 1.20377903 0.067522992 0.012679147 5.29E-10 9.276306204 -0.066574398 KES(ph)PS(ph)ST(ph)GS(ph)ST(ph)WK ddPTM_HeLa_Curcumin_4h_R1 1 KESPSSTGSSTWK 13 1 C9JFM2;C9JXD6;C9JK00;Q6NV74 C9JFM2 KIAA1211L Uncharacterized protein KIAA1211-like 5 0 KES(0.998)PS(0.807)S(0.36)T(0.748)GS(0.645)S(0.645)T(0.797)WK 70.47 0.0088831 3397000 3556.8 2782 2886 3133 3286.4 3849.1 2863.9 2838.8 3544.7 3384.6 TRUE FALSE FALSE 3275.275527 3022.463684 2992.957699 3120.036476 3247.211826 3050.753272 2944.253326 3704.337052 3155.855278 3502.214598 0.935201266 0.863014986 0.854590036 0.890875299 0.927188136 0.871092615 0.8406833 1.057712755 0.901102771 1 11.77405177 -8.145731814 1.002797285 0.988336502 0.897600087 0.010305485 0.065022158 0.402334302 0.851826235 0.016521933 0.012046253 7.15E-09 8.145731814 -0.090736415 KES(ph)PS(ph)STGS(ph)S(ph)T(ph)WK ddPTM_HeLa_Curcumin_4h_R1 1 KESPSSTGSSTWK 13 1 C9JFM2;C9JXD6;C9JK00;Q6NV74 C9JFM2 KIAA1211L Uncharacterized protein KIAA1211-like 5 0 KES(0.997)PS(0.411)S(0.553)T(0.409)GS(0.883)S(0.883)T(0.863)WK 77.192 0.006424 14781000 2309.6 2589.2 2369.8 2663 2361.8 2971.8 2357.6 2752.7 2319.1 2149.4 TRUE FALSE FALSE 2126.792723 2812.998911 2457.626873 2651.981212 2333.637078 2355.415181 2423.747911 3591.985558 2064.700532 2224.09149 0.956252354 1.264785609 1.105002597 1.192388543 1.049254083 1.059045993 1.089769878 1.615034981 0.928334352 1 11.11900042 -4.247819954 3.379074672 1.033327727 1.700471568 0.712597292 0.10153566 0.141723655 2.608586188 0.015608403 0.247265998 5.65E-05 4.247819954 0.667143841 KES(ph)PSS(ph)T(ph)GS(ph)S(ph)TWK ddPTM_HeLa_Curcumin_4h_R1 1 KESPSSTGSSTWK 13 1 C9JFM2;C9JXD6;C9JK00;Q6NV74 C9JFM2 KIAA1211L Uncharacterized protein KIAA1211-like 5 0 KES(0.976)PS(0.154)S(0.873)T(0.945)GS(0.732)S(0.732)T(0.588)WK 62.378 0.012104 5137100 955 885.39 1203.3 949.85 1016.1 1276.2 845.5 897.02 1191.7 1082.2 TRUE FALSE FALSE 879.4107423 961.9191664 1247.895357 945.9197724 1003.983671 1011.501734 869.2224545 1170.517269 1060.973491 1119.806369 0.785323933 0.859004907 1.114384942 0.844717264 0.896568995 0.903282712 0.776225675 1.045285418 0.947461562 1 10.12903358 -4.213575914 22.06371837 0.898939061 1.045288177 0.164926163 0.095661317 13290.90732 6126040.843 0.014670661 10.46901875 6.12E-05 4.213575914 0.146349116 KES(ph)PSS(ph)T(ph)GSS(ph)T(ph)WK ddPTM_HeLa_Curcumin_4h_R1 1 KESPSSTGSSTWK 13 1 C9JFM2;C9JXD6;C9JK00;Q6NV74 C9JFM2 KIAA1211L Uncharacterized protein KIAA1211-like 5 0 KES(0.93)PS(0.223)S(0.836)T(0.978)GS(0.498)S(0.791)T(0.744)WK 74.89 0.0072723 9779000 3346.5 3127.9 3905.9 3402.9 3546.3 4140.4 3585.2 4228.7 3441.9 3229.3 TRUE FALSE FALSE 3081.620994 3398.261738 4050.65609 3388.819701 3504.012689 3281.634368 3685.791063 5518.011163 3064.332181 3341.517935 0.922221893 1.016981445 1.212220365 1.014155772 1.048629023 0.982078933 1.103028963 1.65134866 0.917047953 1 11.7062879 -4.249067239 2.779099045 0.995040814 1.785424577 0.85091239 0.079198584 0.130022185 1.323182161 0.01199077 0.236427127 5.64E-05 4.249067239 0.790383763 KES(ph)VSPEDSEK ddPTM_HeLa_Curcumin_4h_R1 1 KESVSPEDSEK 11 1 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 0 KES(0.558)VS(0.432)PEDS(0.01)EK 94.532 0.0067617 20577000 6682 4615 6191.8 8045.3 8010.9 8213.7 7503.1 4484.2 7185.6 5873.7 TRUE FALSE FALSE 6153.112649 5013.900036 6421.273555 8012.01068 7915.37525 6510.086033 7713.616792 5851.411937 6397.357657 6077.810638 1.012389661 0.82495167 1.056510961 1.318239603 1.302339892 1.071123538 1.269143982 0.962749958 1.052576008 1 12.56933601 -6.510674278 24.6231861 0.989984085 1.189407461 0.429006132 0.115251834 343.1696525 692363.8491 0.01672311 0.024736156 3.09E-07 6.510674278 0.199423377 KESPS(ph)S(ph)T(ph)GS(ph)S(ph)TWK ddPTM_HeLa_Curcumin_4h_R1 3 KESPSSTGSSTWK 13 1 C9JFM2;C9JXD6;C9JK00;Q6NV74 C9JFM2 KIAA1211L Uncharacterized protein KIAA1211-like 5 0 KES(0.147)PS(0.926)S(0.922)T(0.98)GS(0.837)S(0.781)T(0.408)WK;KES(0.128)PS(0.872)S(0.958)T(0.951)GS(0.71)S(0.71)T(0.671)WK;KES(0.009)PS(0.993)S(0.998)T(0.961)GS(0.7)S(0.7)T(0.64)WK ;; 75.462 0.005704 7383400 4448.92 4097.11 4621.36 4085.36 4521.39 5192.76 4572.2 4812.74 4665.82 4386.37 TRUE FALSE FALSE 4096.783288 4451.245932 4792.631667 4068.455863 4467.475377 4115.723042 4700.483627 6280.122271 4153.991219 4538.796031 0.902614539 0.980710722 1.055925764 0.896373363 0.984286438 0.906787398 1.035623455 1.383653777 0.915218748 1 12.14809394 -4.27703981 3.135990509 0.957862425 1.440266082 0.871208107 0.049197461 0.086240814 1.314671452 0.007137486 0.099993808 5.28E-05 4.27703981 0.482403657 VASGSTATAAAGPSCALK(ac)AGK ddPTM_HeLa_Curcumin_4h_R1 2 VASGSTATAAAGPSCALKAGK 21 1 P41134-2;P41134 P41134-2 ID1 DNA-binding protein inhibitor ID-1 0 1 ; VASGSTATAAAGPSCALK(1)AGK;VASGSTATAAAGPSCALK(1)AGK 337.03 5.40E-205 19660100 7469.7 5633.8 7480.6 6583.2 6739.6 8215.6 3933.6 513.19 6385.2 6637.9 FALSE TRUE FALSE 6878.465363 6120.760568 7757.837617 6555.960463 6659.234672 6511.591951 4043.966229 669.6592686 5684.759535 6868.566531 1.001441179 0.891126342 1.129469676 0.954487437 0.96952321 0.94802779 0.588764222 0.097496219 0.827648609 1 12.74579332 -4.440279589 1.866701079 0.997514693 2.87E-20 0.9220274 0.078693019 0.068925458 0.321410331 0.007511165 0.105001359 3.63E-05 4.440279589 -0.997514693 down KESVS(ph)PEDSEK ddPTM_HeLa_Curcumin_4h_R1 2 KESVSPEDSEK 11 1 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 0 KES(0.008)VS(0.989)PEDS(0.003)EK;KES(0.202)VS(0.68)PEDS(0.118)EK ; 173.06 0.00035053 20989800 6314.4 3778.8 6211.5 7071.7 6859.1 7053.4 6685.6 4279.9 6856.2 5053.9 TRUE FALSE FALSE 5814.608577 4105.422634 6441.703654 7042.439179 6777.309712 5590.445332 6873.179943 5584.821808 6104.092013 5229.522649 1.111881326 0.7850473 1.231795727 1.346669601 1.295971003 1.069016372 1.314303504 1.067941031 1.16723694 1 12.35246355 -6.626573009 20.79811061 1.032985613 1.227526836 0.37747435 0.128001538 2.658299887 523.85297 0.018589108 0.026288961 2.36E-07 6.626573009 0.194541222 KESVSPEDS(ph)EK ddPTM_HeLa_Curcumin_4h_R1 1 KESVSPEDSEK 11 1 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 0 KES(0.002)VS(0.294)PEDS(0.704)EK 122.52 0.0060977 4064600 865.4 628.7 832.23 1168.1 981.53 1160.7 988.87 644 1169.2 778.55 TRUE FALSE FALSE 796.9026768 683.0420266 863.0731759 1163.266712 969.8258958 919.9577362 1016.615031 840.3526354 1040.941685 805.6045545 0.989198326 0.847862667 1.071336018 1.443967397 1.203848576 1.14194704 1.261928107 1.043132925 1.292124876 1 9.65392803 -6.513873409 24.9964489 0.982579912 1.220374971 0.259109654 0.142784146 235.519825 653741.5744 0.015355845 0.022401817 3.06E-07 6.513873409 0.23779506 KESYSIYVYK ddPTM_HeLa_Curcumin_4h_R1 3 KESYSIYVYK 10 1 P33778;Q16778;P06899;Q8N257 P33778;Q16778;Q8N257 HIST1H2BB;HIST2H2BE;HIST1H2BJ;HIST3H2BB Histone H2B type 1-B;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 3-B 0 0 ;; ;; 137.01 0.00014297 26915600 19234.7 12167.3 15597.2 14111.1 15097.7 31158.5 22690.9 20217.4 17084.3 14590.5 FALSE FALSE TRUE 17712.2532 13218.9872 16175.24595 14052.71201 14917.66979 24695.87587 23327.54558 26381.59219 15210.19503 15097.51879 1.173189677 0.875573489 1.07138439 0.930796126 0.988087513 1.635757254 1.545124461 1.747412443 1.007463229 1 13.88202385 -5.257909662 24.9894673 1.049859472 1.633000737 0.903685278 0.094416325 76.81776725 543846.1344 0.01501799 0.036653735 5.52E-06 5.257909662 0.583141265 KESYSVYVYK ddPTM_HeLa_Curcumin_4h_R1 2 KESYSVYVYK 10 1 P58876;P62807;P57053;O60814;Q5QNW6;Q5QNW6-2;Q93079;U3KQK0;Q99877;Q99879;Q99880 P58876;P62807;Q5QNW6;Q93079;U3KQK0;Q99879;Q99880 HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BF;HIST1H2BH;HIST1H2BN;HIST1H2BM;HIST1H2BL Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-F;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-M;Histone H2B type 1-L 0 0 ; ; 134.13 0.00025555 99133000 13406.6 9377 12280.8 11339 10786.8 16768.2 14006.4 12808.5 11149.1 9764.5 FALSE FALSE TRUE 12345.45346 10187.5061 12735.93725 11292.08222 10658.17446 13290.2863 14399.38189 16713.75269 9926.071624 10103.81565 1.221860522 1.008283054 1.260507683 1.117605726 1.054866283 1.315373 1.425142975 1.654202063 0.982408228 1 13.3026126 -4.596288132 1.230964636 1.107986221 1.733715714 0.797590823 0.0928833 0.312381005 0.585830893 0.015047728 0.211909851 2.53E-05 4.596288132 0.625729493 KET(ph)ES(ph)EAEDNLDDLEK ddPTM_HeLa_Curcumin_4h_R1 4 KETESEAEDNLDDLEK 16 1 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 0 KET(1)ES(1)EAEDNLDDLEK;KET(1)ES(1)EAEDNLDDLEK;KET(1)ES(1)EAEDNLDDLEK;KET(1)ES(1)EAEDNLDDLEK ;;; 100.46 0.0020885 1438048000 29178.3 26469.6 25494.4 27991.8 26668.9 31111.5 25878 26169.8 30565.7 27107.5 TRUE FALSE FALSE 26868.80677 28757.51428 26439.24489 27875.97735 26350.89079 24658.6242 26604.06703 34148.85155 27212.71918 28049.48361 0.957907359 1.0252422 0.942592928 0.99381428 0.939442991 0.879111521 0.948469049 1.217450276 0.970168277 1 14.77568659 -4.2583802 24.94693424 0.970142587 1.217450369 0.793980491 0.038852711 102.6118384 836733.4563 0.005727235 0.054558224 5.52E-05 4.2583802 0.247307782 KET(ph)ESEAEDNLDDLEK ddPTM_HeLa_Curcumin_4h_R1 4 KETESEAEDNLDDLEK 16 1 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 KET(0.5)ES(0.5)EAEDNLDDLEK;KET(0.911)ES(0.089)EAEDNLDDLEK;KET(0.843)ES(0.157)EAEDNLDDLEK;KET(0.743)ES(0.257)EAEDNLDDLEK ;;; 117.48 0.00057326 3398683000 12088.5 10847.5 11592 12702.9 11951.2 13436.6 11742.2 13005.2 14657.2 12013.7 TRUE FALSE FALSE 11131.68247 11785.10956 12021.60972 12650.33877 11808.68975 10649.6977 12071.65453 16970.42561 13049.34183 12431.17518 0.895465015 0.948028597 0.967053359 1.017630158 0.949925455 0.856692754 0.97107911 1.365150548 1.049727129 1 13.60167507 -4.263963725 5.35586383 0.949205318 1.381088153 0.833020575 0.054005889 0.039942484 4.140098724 0.00712743 0.063095468 5.45E-05 4.263963725 0.431882835 KET(ph)SPESSLIQDEIAVK ddPTM_HeLa_Curcumin_4h_R1 1 KETSPESSLIQDEIAVK 17 1 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 KET(0.473)S(0.303)PES(0.204)S(0.021)LIQDEIAVK 107.39 0.00070621 18116000 3622.3 2841.3 3280.1 3221.3 3630.7 4122.7 3217.3 2907.4 3338.7 2865 TRUE FALSE FALSE 3335.591133 3086.889311 3401.663391 3207.971114 3587.406274 3267.605548 3307.568779 3793.852876 2972.452963 2964.558537 1.125156104 1.041264415 1.147443489 1.082107529 1.210097972 1.102223318 1.11570365 1.2797362 1.002662935 1 11.53360157 -13.52287849 0.025247192 1.86E-05 1.866216923 0.588692449 0.053532815 907.3412137 1.843643542 96.9897888 47.54360541 3.00E-14 13.52287849 1.866198368 KETES(ph)EAEDNLDDLEK ddPTM_HeLa_Curcumin_4h_R1 9 KETESEAEDNLDDLEK 16 1 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 KET(0.036)ES(0.964)EAEDNLDDLEK;KET(0.024)ES(0.976)EAEDNLDDLEK;KET(0.235)ES(0.765)EAEDNLDDLEK;KET(0.038)ES(0.962)EAEDNLDDLEK;KET(0.237)ES(0.763)EAEDNLDDLEK;KET(0.023)ES(0.977)EAEDNLDDLEK;KET(0.092)ES(0.908)EAEDNLDDLEK;KET(0.022)ES(0.978)EAEDNLDDLEK;KET(0.306)ES(0.694)EAEDNLDDLEK ;;;;;;;; 152.64 0.00015652 5125558000 36179.5 31942 36090.4 35408.4 34505.1 41236.5 36228.6 39161.9 40439.2 36677.6 TRUE FALSE FALSE 33315.8544 34702.92415 37427.94197 35261.88942 34093.64922 32683.58507 37245.07701 51102.18303 36003.12093 37952.14387 0.877838536 0.914386399 0.986187819 0.929114559 0.89833263 0.861178888 0.981369515 1.346490022 0.948645248 1 15.21189376 -4.269719992 3.990031819 0.933485934 1.380659828 0.899037462 0.041858012 0.063645016 2.097986102 0.007458985 0.081078991 5.37E-05 4.269719992 0.447173894 KETQS(ph)PEQVK ddPTM_HeLa_Curcumin_4h_R1 1 KETQSPEQVK 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 KET(0.1)QS(0.9)PEQVK 106.29 0.014496 42026000 4528.3 4853.6 4692.7 3618.5 4193.8 4499.3 4135.1 3775.4 3577.2 4285.7 TRUE FALSE FALSE 4169.880277 5273.123557 4866.61559 3603.527606 4143.791674 3566.094462 4251.119777 4926.50208 3184.79011 4434.627756 0.940299954 1.189079185 1.097412423 0.81258852 0.934417025 0.804147419 0.958619305 1.110916711 0.718164023 1 12.11459729 -6.265555726 24.98934897 0.999408024 0.919958374 0.049138263 0.138304589 640.2442217 3886768.707 0.017066007 0.026637607 5.43E-07 6.265555726 -0.079449651 KETSFGS(ph)SENITMTSLSK ddPTM_HeLa_Curcumin_4h_R1 1 KETSFGSSENITMTSLSK 18 1 Q9UMZ2-6;Q9UMZ2-9;Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2 Q9UMZ2-6 SYNRG Synergin gamma 1 0 KETS(0.001)FGS(0.886)S(0.112)ENITMTSLSK 84.025 0.0023346 14605000 1918.5 1389.1 1542.6 1928.4 1601.3 2054.6 1638.4 723.31 1539.3 1734.6 TRUE FALSE FALSE 1766.648701 1509.167614 1599.770113 1920.420792 1582.205543 1628.4528 1684.369094 943.8438893 1370.442641 1794.877221 0.984272729 0.840819415 0.891297797 1.069945492 0.881511852 0.907278103 0.938431373 0.525854291 0.76353002 1 10.80966944 -3.959290749 1.781991494 0.969075104 7.25E-11 0.567807677 0.094392982 0.837881762 1.3253783 0.010119897 1.773350724 0.000109827 3.959290749 -0.969075104 VHGLPTTS(ph)PSGMNMAELAQQVVK ddPTM_HeLa_Curcumin_4h_R1 2 VHGLPTTSPSGMNMAELAQQVVK 23 0 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 0 VHGLPT(0.026)T(0.192)S(0.562)PS(0.221)GMNMAELAQQVVK;VHGLPT(0.198)T(0.176)S(0.313)PS(0.313)GMNMAELAQQVVK ; 86.006 0.00020716 49624000 4105.5 3391.8 3693.8 2813.7 3171.4 3841.2 1712.31 858.88 4029.9 3176.3 TRUE FALSE FALSE 3780.545343 3684.972078 3830.695477 2802.057655 3133.583126 3044.491821 1760.35281 1120.748558 3587.830052 3286.676189 1.150264013 1.121185011 1.165522631 0.852550569 0.953420096 0.926313286 0.535602752 0.340997559 1.091628699 1 11.68241361 -4.416310107 0.857347592 1.075337523 1.03E-14 0.891976061 0.085577675 0.455275059 0.284022016 0.015113467 0.436118551 3.83E-05 4.416310107 -1.075337523 down KETTSGTSTEPVKNSS(ph)PAPPQPAPGK ddPTM_HeLa_Curcumin_4h_R1 2 KETTSGTSTEPVKNSSPAPPQPAPGK 26 2 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 0 KETTSGTSTEPVKNS(0.051)S(0.949)PAPPQPAPGK;KETTSGTSTEPVKNS(0.263)S(0.737)PAPPQPAPGK ; 96.633 1.96E-06 264650000 7354.2 5950.8 6425.5 6511.4 6306.2 7398.4 5605.3 4664.6 6726.1 5953.9 TRUE FALSE FALSE 6772.10731 6465.160636 6663.634682 6484.457552 6231.002684 5863.888443 5762.569632 6086.815067 5988.263658 6160.797582 1.099225745 1.04940319 1.081618832 1.052535401 1.011395457 0.951806704 0.935360975 0.987991406 0.971994872 1 12.58890142 -5.473157052 2.858857444 1.051329028 0.956078676 0.497962235 0.037000555 0.159419218 2.571045625 0.005815961 0.013859298 3.36E-06 5.473157052 -0.095250352 KEWSGLLEELAR ddPTM_HeLa_Curcumin_4h_R1 1 KEWSGLLEELAR 12 1 Q01813;Q01813-2;Q5VSR5;V9GYV7 Q01813 PFKP "ATP-dependent 6-phosphofructokinase, platelet type" 0 0 99.844 0.013754 8191600 2131.8 1918 2050.8 1782.6 1955.3 4123.5 3063.9 2634.1 1985.3 2000.1 FALSE FALSE TRUE 1963.065781 2083.783374 2126.804452 1775.224074 1931.984325 3268.239619 3149.864788 3437.224964 1767.517557 2069.603326 0.948522722 1.006851577 1.027638691 0.857760543 0.933504648 1.579162334 1.521965465 1.660813413 0.854036875 1 11.01513856 -5.259265012 24.9981383 0.970056268 1.580778952 0.951921329 0.065805749 24.00586326 275986.7612 0.007795057 0.018858497 5.50E-06 5.259265012 0.610722684 KEYEEDDILAS(ph)DDPSSIEQYENTR ddPTM_HeLa_Curcumin_4h_R1 1 KEYEEDDILASDDPSSIEQYENTR 24 1 Q96RS0 Q96RS0 TGS1 Trimethylguanosine synthase 1 0 KEYEEDDILAS(0.701)DDPS(0.14)S(0.14)IEQY(0.003)ENT(0.016)R 49.515 0.012352 43797000 2544.3 2149.5 2142.3 2027.9 2069.9 2888.3 1682.3 1004.9 2102.2 1622.6 TRUE FALSE FALSE 2342.91597 2335.293202 2221.695523 2019.509087 2045.217794 2289.234022 1729.50081 1311.289384 1871.593919 1678.985229 1.395435725 1.39089562 1.323237086 1.202815279 1.21812733 1.363462872 1.030086972 0.781001144 1.114717323 1 10.71337382 -4.462757945 3.44768204 1.227550493 0.793739291 0.586930028 0.122845149 0.191914109 4.151835439 0.023421047 0.160973535 3.45E-05 4.462757945 -0.433811202 KFAETQPK ddPTM_HeLa_Curcumin_4h_R1 2 KFAETQPK 8 1 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 0 ; ; 93.178 0.0056373 40358000 20236 17398.7 18326.7 17155.4 17307.1 22358 16856.5 17369.3 18085.5 18495.3 FALSE FALSE TRUE 18634.29925 18902.5661 19005.90362 17084.4155 17100.72414 17720.69877 17329.44802 22665.11961 16101.5659 19138.0103 0.973680072 0.987697561 0.993097157 0.892695491 0.89354765 0.925942587 0.905498939 1.184298642 0.841339598 1 14.22415323 KFDQLLAEEK ddPTM_HeLa_Curcumin_4h_R1 2 KFDQLLAEEK 10 1 P35579;P35579-2;P35580;P35580-5;P35580-2;P35580-3;P35580-4;P35749-4;P35749-3;P35749;P35749-2;Q7Z406;Q7Z406-6;Q7Z406-2;A0A0C4DFM8;A1L2Z2 P35579;P35580;P35749-4;Q7Z406 MYH9;MYH10;MYH11;MYH14 Myosin-9;Myosin-10;Myosin-11;Myosin-14 0 0 ; ; 131.17 0.00037134 6948200 13592.4 8922.1 12013.2 11309.6 11911.2 11971.3 10930.1 9011.6 10765.8 10168.9 FALSE FALSE TRUE 12516.5472 9693.286568 12458.41976 11262.80387 11769.16672 9488.317436 11236.76919 11759.19536 9584.818675 10522.26852 1.189529347 0.921216423 1.184005116 1.070377918 1.118500892 0.901736866 1.067903672 1.117553248 0.91090801 1 13.36115815 T(ph)PSSSPPIT(ph)PPASETK ddPTM_HeLa_Curcumin_4h_R1 1 TPSSSPPITPPASETK 16 0 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 2 0 T(0.483)PS(0.079)S(0.086)S(0.365)PPIT(0.986)PPAS(0.001)ETK 141.6 0.0014049 21434000 3996.3 2929 3284.9 3305.1 3419.3 3588.7 2254.9 1203.6 3610.5 3160.3 TRUE FALSE FALSE 3679.988638 3182.169709 3406.641284 3291.424372 3378.527081 2844.363167 2318.166425 1570.572099 3214.437183 3270.12019 1.125337426 0.973104817 1.041748036 1.006514801 1.033150736 0.869803861 0.708893341 0.480279625 0.982972183 1 11.67512795 -4.414924597 0.968017255 1.052311273 0.258480566 0.935082725 0.046344353 0.288841829 0.241937284 0.008239788 0.22490855 3.85E-05 4.414924597 -0.793830707 down HASAPS(ph)HVQPSDSEK ddPTM_HeLa_Curcumin_4h_R1 1 HASAPSHVQPSDSEK 15 0 A0A3B3IRT3;O60343-2;O60343-3;O60343 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 1 0 HAS(0.157)APS(0.843)HVQPSDSEK 125.86 0.00031701 43482000 6764.8 5335.8 5247.7 4967.1 7178.4 7807.6 4087.3 1390.2 7190.2 5179.7 TRUE FALSE FALSE 6229.358942 5797.002776 5442.184378 4946.547456 7092.802268 6188.21575 4201.978638 1814.06558 6401.453049 5359.694189 1.162260144 1.081592078 1.015390839 0.922915988 1.323359509 1.154583738 0.783995969 0.338464382 1.194369086 1 12.38793497 -4.413814405 2.641205112 1.084394245 0.298742613 0.820846537 0.111153287 0.110047957 1.199229593 0.01591696 0.160683245 3.86E-05 4.413814405 -0.785651632 down KFGNPGEK(ac)LVK ddPTM_HeLa_Curcumin_4h_R1 2 KFGNPGEKLVK 11 2 P17844-2;P17844;J3KTA4;J3QRQ7;J3QR02;J3KRX8;J3KTQ4;X6RLV5;J3QKN9 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 1 ; KFGNPGEK(1)LVK;KFGNPGEK(1)LVK 128.08 1.41E-08 0 14113.1 11648.8 11977.8 11242.1 12845.8 21506.4 15340.4 17603.8 14551 12421.9 FALSE TRUE FALSE 12996.03324 12655.67037 12421.7078 11195.58317 12692.62222 17045.73021 15770.81034 22971.11758 12954.7917 12853.5601 1.011084333 0.984604286 0.966402126 0.871010295 0.987479121 1.32614856 1.226960485 1.787140481 1.007875764 1 13.64988038 -3.484356376 0.818418772 0.990522269 3.824728533 0.889235568 0.085451468 1.616011544 0.316153786 0.01329089 5.62849727 0.000327826 3.484356376 2.834206265 KFGYVDFESAEDLEK ddPTM_HeLa_Curcumin_4h_R1 2 KFGYVDFESAEDLEK 15 1 P19338 P19338 NCL Nucleolin 0 0 ; ; 199.33 5.32E-07 163492000 13960.8 10283.4 11902.8 12009.9 11601.5 16422.8 13749.2 12656.1 13875.4 12725 FALSE FALSE TRUE 12855.78795 11172.25127 12343.92824 11960.20622 11463.15969 13016.52616 14134.96555 16514.88663 12353.30333 13167.1928 0.976349943 0.848491508 0.937476076 0.908333796 0.870584935 0.988557421 1.07349879 1.254245068 0.93818808 1 13.68466018 -4.372175339 1.984706703 0.960296677 1.302196564 0.783017995 0.051534152 0.252170354 1.253642926 0.008662366 0.143403176 4.24E-05 4.372175339 0.341899887 KFNGEDIDTIS(ph)PTLGFNIK ddPTM_HeLa_Curcumin_4h_R1 3 KFNGEDIDTISPTLGFNIK 19 1 V9GYD0;P36404-2;P36404 V9GYD0 ARL2-SNX15;ARL2 ADP-ribosylation factor-like protein 2 1 0 KFNGEDIDT(0.02)IS(0.964)PT(0.015)LGFNIK;KFNGEDIDT(0.016)IS(0.965)PT(0.019)LGFNIK;KFNGEDIDT(0.076)IS(0.922)PT(0.002)LGFNIK ;; 98.21 0.00054872 116283000 11271.6 9076.4 9480 10029.7 8378.5 11747.7 10358.9 10167.3 11487.5 10740.5 TRUE FALSE FALSE 10379.44097 9860.923572 9831.337139 9988.199759 8278.59186 9311.094596 10649.54285 13267.26297 10227.34999 11113.73158 0.933929427 0.887273865 0.884611714 0.898726021 0.744897589 0.837800925 0.958232866 1.193772126 0.920244467 1 13.44005568 -8.338246787 0.907330305 0.991077053 0.906886072 0.002999461 0.110669826 0.967742421 1.66878721 0.038816239 0.023867106 4.59E-09 8.338246787 -0.084190981 KFNHDGEEEEEDDDYGSR ddPTM_HeLa_Curcumin_4h_R1 2 KFNHDGEEEEEDDDYGSR 18 1 Q6PJT7;Q6PJT7-5;H0YJA2;Q6PJT7-9;Q6PJT7-2;Q6PJT7-3;Q6PJT7-11;Q6PJT7-4;G3V256;Q6PJT7-10;G3V5I6 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 0 0 ; ; 151.11 2.36E-05 24400700 6149.5 4595.7 4967.4 5346.1 5423 5981.2 4425.3 3715.7 6338.9 5378 FALSE FALSE TRUE 5662.760586 4992.93183 5151.496214 5323.979255 5358.334267 4740.631698 4549.462008 4848.599825 5643.538529 5564.8851 1.017588052 0.89722101 0.925714749 0.956709646 0.962883181 0.851883123 0.817530268 0.871284804 1.014133882 1 12.44213618 -5.458951308 0.416546069 1.011720565 0.7934283 0.668284748 0.038512972 0.960629563 0.216189751 0.012783346 0.090003728 3.48E-06 5.458951308 -0.218292264 KFSGFSAKPNNSGEAPS(ph)SPTPK ddPTM_HeLa_Curcumin_4h_R1 2 KFSGFSAKPNNSGEAPSSPTPK 22 2 K7ENR9;K7ERZ5;P49916-4;P49916-3;P49916-2;P49916 K7ENR9 LIG3 DNA ligase 3 1 0 KFSGFSAKPNNS(0.111)GEAPS(0.639)S(0.237)PT(0.013)PK;KFSGFSAKPNNS(0.001)GEAPS(0.439)S(0.439)PT(0.12)PK ; 86.039 0.00039848 172555000 9291.3 7034.9 7305.4 8787.5 8503 9554.4 6939.9 5157.6 8536.3 7650.6 TRUE FALSE FALSE 8555.883801 7642.965409 7576.14455 8751.139653 8401.607278 7572.70974 7134.614916 6730.128497 7599.889247 7916.457781 1.080771734 0.965452684 0.957011931 1.105436282 1.061283659 0.956578049 0.901238295 0.850143926 0.960011341 1 12.95063933 -4.874839713 2.242572995 1.033418587 0.863541408 0.541654325 0.051339947 0.158899749 1.547998062 0.007359682 0.032684193 1.33E-05 4.874839713 -0.169877178 KGAAIPAK(ac)GAK ddPTM_HeLa_Curcumin_4h_R1 1 KGAAIPAKGAK 11 2 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 KGAAIPAK(1)GAK 79.07 0.019822 0 7470 5440.1 5719.2 5899.6 6336.2 8065.2 6592.2 6626.1 7166.2 5801.8 FALSE TRUE FALSE 6878.741618 5910.318003 5931.158583 5875.189018 6260.644953 6392.386606 6777.15939 8646.367387 6380.085789 6003.412118 1.145805332 0.984493133 0.987964589 0.97864163 1.042847772 1.064792235 1.128884584 1.440242185 1.062743264 1 12.55156699 -4.205673129 2.143021923 1.049590876 1.583186268 0.853831293 0.050219006 0.303717785 1.365927081 0.009598538 0.325984499 6.23E-05 4.205673129 0.533595392 KGAANASGSS(ph)PDAPAK ddPTM_HeLa_Curcumin_4h_R1 4 KGAANASGSSPDAPAK 16 1 E7EPJ7;O75962-5;O75962-4;O75962 E7EPJ7 TRIO Triple functional domain protein 1 0 KGAANAS(0.002)GS(0.055)S(0.943)PDAPAK;KGAANASGS(0.039)S(0.961)PDAPAK;KGAANAS(0.004)GS(0.08)S(0.916)PDAPAK;KGAANASGS(0.102)S(0.898)PDAPAK ;;; 199.61 7.02E-08 219514000 36710.6 31417.5 36841.9 36096 39596.5 35757.7 27028 16517.7 32783.7 29141.3 TRUE FALSE FALSE 33804.91727 34133.08871 38207.29322 35946.64432 39124.3376 28341.14995 27786.33294 21553.87069 29187.41013 30153.95801 1.121077282 1.131960478 1.267073902 1.19210368 1.297485975 0.939881588 0.921482113 0.714794081 0.967946235 1 14.88005976 -4.623608908 1.821140537 1.103108129 0.722226124 0.588712486 0.109265549 0.286501399 1.532578001 0.017092828 0.146131197 2.38E-05 4.623608908 -0.380882005 SSSLEMTPYNTPQLS(ph)PATTPANKK ddPTM_HeLa_Curcumin_4h_R1 2 SSSLEMTPYNTPQLSPATTPANKK 24 1 Q14C86-4;Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;F8W9S7;Q14C86-3;H0Y4E7;H0Y7I9;C9IZ08;B4DGD8;B0QZ65;A0A0A0MQV8 Q14C86-4 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 0 SSSLEMTPYNTPQLS(0.999)PAT(0.001)TPANKK;SSSLEMTPY(0.002)NT(0.036)PQLS(0.961)PAT(0.001)TPANKK ; 136.01 1.41E-06 124178000 6662.7 5408.9 5536.7 5974 5539.8 6268.4 3618.5 1355.97 6944.8 6792.6 TRUE FALSE FALSE 6135.340265 5876.421214 5741.894973 5949.281171 5473.741503 4968.263181 3720.025371 1769.399011 6182.972815 7028.642344 0.872905458 0.836067753 0.816928034 0.846433903 0.778776503 0.706859581 0.529266562 0.251741222 0.879682378 1 12.77903033 -4.412858049 0.601105005 0.93179737 5.10E-37 0.925522404 0.055611836 0.617350856 0.168798466 0.012304284 0.382606846 3.86E-05 4.412858049 -0.93179737 down KGAAPAPPGK(ac)TGPAVAK ddPTM_HeLa_Curcumin_4h_R1 2 KGAAPAPPGKTGPAVAK 17 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 0 1 ; KGAAPAPPGK(1)TGPAVAK;KGAAPAPPGK(1)TGPAVAK 167.29 4.73E-05 17215600 11680.7 8967.7 9392 9563.9 9114.4 12263.7 10962.6 11304.5 10592.6 9081.8 FALSE TRUE FALSE 10756.16027 9742.828029 9740.075782 9524.327116 9005.716733 9720.07038 11270.18105 14751.19001 9430.618281 9397.391874 1.144589947 1.036758726 1.036465853 1.013507497 0.958320867 1.034337028 1.199288186 1.569711065 1.003535705 1 13.1980447 -4.303336126 2.399353079 1.051723927 1.663201885 0.913004614 0.050373475 0.134034724 0.992018474 0.009293698 0.162391921 4.97E-05 4.303336126 0.611477958 KGAGDGS(ph)DEEVDGK ddPTM_HeLa_Curcumin_4h_R1 12 KGAGDGSDEEVDGK 14 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 0 KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK;KGAGDGS(1)DEEVDGK ;;;;;;;;;;; 170.48 0.00031868 4137876500 56913.06 60226.3 60767.75 55994 66624.3 59200.53 52818.04 45006.12 50641.46 48673.07 TRUE FALSE FALSE 52408.33125 65431.99301 63019.85627 55762.31166 65829.84874 46921.67275 54299.97205 58728.27881 45086.21854 50364.45556 1.040581709 1.299170065 1.251276432 1.107175905 1.307069599 0.931642608 1.078140753 1.166065991 0.895199164 1 15.6201183 -7.483190046 18.02306704 1.01790202 1.158453712 0.346659303 0.11245493 17.36947222 7888.218081 0.018280307 0.020557124 3.29E-08 7.483190046 0.140551693 KGAGDGS(ph)DEEVDGKADGAEAK ddPTM_HeLa_Curcumin_4h_R1 1 KGAGDGSDEEVDGKADGAEAK 21 2 P35579;P35579-2 P35579 MYH9 Myosin-9 1 0 KGAGDGS(1)DEEVDGKADGAEAK 68.303 0.0026003 222010000 3417.3 2683.9 3341 3006.8 3873.3 3264.9 3009.6 2801.3 2966.8 3120.4 TRUE FALSE FALSE 3146.817099 2915.884357 3464.820399 2994.358658 3827.113427 2587.722937 3094.041276 3655.403474 2641.349463 3228.833668 0.974598701 0.90307667 1.073087299 0.927380896 1.18529284 0.801442008 0.958253535 1.132112661 0.818050644 1 11.65679741 -4.255238442 23.43442247 0.9829776 1.132112825 0.154844488 0.109386329 356.1476123 1345847.115 0.011751003 0.141198759 5.56E-05 4.255238442 0.149135224 KGAGDGS(ph)DEEVDGKADGAEAKPAE ddPTM_HeLa_Curcumin_4h_R1 2 KGAGDGSDEEVDGKADGAEAKPAE 24 3 P35579;P35579-2 P35579 MYH9 Myosin-9 1 0 KGAGDGS(1)DEEVDGKADGAEAKPAE;KGAGDGS(1)DEEVDGKADGAEAKPAE ; 56.573 0.016059 346833000 7329.1 5709.1 6698.4 7513 5789.9 7193.8 5471.6 5645.6 7545.3 6770 TRUE FALSE FALSE 6748.994001 6202.569165 6946.648597 7481.913197 5720.859224 5701.724789 5625.11837 7366.917451 6717.599467 7005.256996 0.963418473 0.885416362 0.991633655 1.068042643 0.816652298 0.813920859 0.802985297 1.051627007 0.958936906 1 12.77422226 -5.748474206 24.99999826 0.980288765 0.862318748 0.303630433 0.078578085 196.0404218 378011.1765 0.01091192 0.021715183 1.78E-06 5.748474206 -0.117970017 KGAILSEEELAAMS(ph)PTAAAVAK ddPTM_HeLa_Curcumin_4h_R1 1 KGAILSEEELAAMSPTAAAVAK 22 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 0 KGAILSEEELAAMS(0.949)PT(0.051)AAAVAK 112.32 8.68E-06 31686000 2962.9 2476.9 2042.6 2848.3 2489 4709.8 3509.6 3168.4 3220.1 2479.3 TRUE FALSE FALSE 2728.383339 2690.992199 2118.300553 2836.514489 2459.320301 3732.93439 3608.06993 4134.430574 2866.863086 2565.45549 1.063508351 1.048933497 0.825701541 1.10565726 0.958629105 1.455076653 1.406405195 1.611577589 1.117486971 1 11.32499928 -5.25290112 19.26566638 1.018080872 1.482559872 0.847776946 0.091999137 6.900199127 15567.68018 0.01156756 0.028748481 5.59E-06 5.25290112 0.464479 KGAVAEDGDELRTEPEAK ddPTM_HeLa_Curcumin_4h_R1 1 KGAVAEDGDELRTEPEAK 18 2 G3V5D9;A0A0C4DGK8;G3V3C7;G3V5Q1;G3V3M6;P27695 G3V5D9 APEX1 "DNA-(apurinic or apyrimidinic site) lyase;DNA-(apurinic or apyrimidinic site) lyase, mitochondrial" 0 0 57.703 0.015194 2984500 2514.7 2158.9 1970.7 1921.2 2034.3 2848.9 2072.1 2180.4 2247.9 2007.9 FALSE FALSE TRUE 2315.658842 2345.505696 2043.735876 1913.250583 2010.042301 2258.006026 2130.237549 2845.193923 2001.310994 2077.674376 1.114543679 1.12890919 0.98366515 0.920861616 0.967448184 1.086794953 1.025299043 1.369412819 0.963245741 1 11.02075385 -4.259687547 24.47071534 1.041473325 1.369412967 0.693897938 0.068196958 56.11806372 783801.2093 0.010213881 0.08764201 5.50E-05 4.259687547 0.327939642 KGAVECCPNCR ddPTM_HeLa_Curcumin_4h_R1 1 KGAVECCPNCR 11 1 P31689;P31689-2 P31689 DNAJA1 DnaJ homolog subfamily A member 1 0 0 81.625 0.011622 1014800 197.73 312.17 291.37 325.03 269.77 476.34 403 370.09 345.92 195.16 FALSE FALSE TRUE 182.0794619 339.1525838 302.1684285 323.685112 266.5531689 377.5417145 414.3070954 482.9287373 307.9734414 201.9417955 0.901643275 1.679457108 1.496314459 1.602863395 1.319950475 1.869557085 2.05161638 2.391425392 1.52506043 1 7.657795723 -2.688320295 0.245243665 0.863306181 5.45968846 0.57978668 0.278754867 6.580977447 0.167464293 0.14300643 10.53735341 0.00204965 2.688320295 4.596382279 KGDECELLGHSK ddPTM_HeLa_Curcumin_4h_R1 2 KGDECELLGHSK 12 1 P49411 P49411 TUFM "Elongation factor Tu, mitochondrial" 0 0 ; ; 52.247 0.012553 6359500 8320.3 7250.5 7157.5 8630.2 9107.5 12255.5 7210.3 6025.5 9998.9 7371.3 FALSE FALSE TRUE 7661.739475 7877.200912 7422.763246 8594.490519 8998.899011 9713.571152 7412.601612 7862.647212 8902.045686 7627.452126 1.004495256 1.032743409 0.973164187 1.126783935 1.179804063 1.273501425 0.971831942 1.030835341 1.167106071 1 12.8969855 -6.254114369 24.27632819 1.002985927 1.120744872 0.114031623 0.092649485 334.6470404 1109075.291 0.011846561 0.019369171 5.57E-07 6.254114369 0.117758944 KGDRS(ph)PEPGQTWTR ddPTM_HeLa_Curcumin_4h_R1 2 KGDRSPEPGQTWTR 14 2 Q09666;E9PKR9;E9PLK4;E9PJZ0;E9PJC6;Q09666-2 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 KGDRS(0.997)PEPGQT(0.003)WTR;KGDRS(1)PEPGQTWTR ; 105.02 0.0015527 173128000 5883.6 4611.8 5097.3 4763.2 4078.3 3521.9 3096.2 5981.9 5998.2 4980.1 TRUE FALSE FALSE 5417.906852 5010.423442 5286.210422 4743.49114 4029.668936 2791.41824 3183.071039 7805.753773 5340.212467 5153.158104 1.051376019 0.972301517 1.025819568 0.920501767 0.781980458 0.541690781 0.617693262 1.514751462 1.036298976 1 12.33124114 -6.034133961 3.442658748 1.019924301 0.824444232 0.070646892 0.246067199 0.390199631 9.537351961 0.035395593 0.063292833 9.24E-07 6.034133961 -0.195480069 KGDS(ph)SAEELK ddPTM_HeLa_Curcumin_4h_R1 1 KGDSSAEELK 10 1 P26373;P26373-2 P26373 RPL13 60S ribosomal protein L13 1 0 KGDS(0.699)S(0.301)AEELK 106.79 0.014162 42023000 4185.7 4678.2 4734.4 3364.2 4514.8 5299.7 3501.4 4075.6 3493.8 4205 TRUE FALSE FALSE 3854.397428 5082.562762 4909.861029 3350.279832 4460.963959 4200.48248 3599.63986 5318.231678 3110.538881 4351.123437 0.885839596 1.168103557 1.128412259 0.769980415 1.025244175 0.965378836 0.827289759 1.222266331 0.714881783 1 12.08717223 KGDSS(ph)AEELKLATQLTGPVMPVR ddPTM_HeLa_Curcumin_4h_R1 1 KGDSSAEELKLATQLTGPVMPVR 23 2 P26373;P26373-2 P26373 RPL13 60S ribosomal protein L13 1 0 KGDS(0.215)S(0.785)AEELKLATQLTGPVMPVR 54.457 0.0037618 23083000 995.95 696.96 636.81 780.14 686.42 706.73 633.1 459.77 886.23 1227 TRUE FALSE FALSE 917.1195066 757.2021168 660.4107388 776.9119874 678.2348898 560.1462315 650.8630821 599.9517565 789.0127862 1269.638159 0.722347151 0.59639206 0.520156656 0.611916066 0.53419542 0.441185725 0.512636673 0.472537591 0.62144697 1 10.31020168 -8.037865176 0.365584782 1.052753864 0.454372006 0.367275269 0.122011862 0.178334502 0.061607841 0.0432184 0.023790855 9.17E-09 8.037865176 -0.598381858 KGDSSAEELK ddPTM_HeLa_Curcumin_4h_R1 1 KGDSSAEELK 10 1 P26373;P26373-2 P26373 RPL13 60S ribosomal protein L13 0 0 94.767 0.0046374 1999500 719.33 1591.1 611.74 709.58 551.7 936.33 553.49 660.71 403.49 575.12 FALSE FALSE TRUE 662.3942715 1728.627594 634.4116225 706.643946 545.1213378 742.1246034 569.0194398 862.1574375 359.2281565 595.1053772 1.113070553 2.904742018 1.066049219 1.187426585 0.916008086 1.247047383 0.956165852 1.448747517 0.603637894 1 9.217001343 KGDVEGSQS(ph)QDEGEGSGESER ddPTM_HeLa_Curcumin_4h_R1 4 KGDVEGSQSQDEGEGSGESER 21 1 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1 0 KGDVEGSQS(1)QDEGEGSGESER;KGDVEGSQS(0.998)QDEGEGS(0.002)GESER;KGDVEGSQS(0.999)QDEGEGSGESER;KGDVEGS(0.026)QS(0.972)QDEGEGS(0.002)GESER ;;; 176.22 5.50E-10 520521000 9323.2 7436.02 8781 9031 8865 9709.1 7966.39 6850.6 8702.07 7465.6 TRUE FALSE FALSE 8585.258882 8078.756435 9106.431585 8993.632115 8759.290665 7695.323216 8189.905463 8939.316404 7747.474693 7725.029044 1.111356195 1.045789781 1.178821663 1.164219845 1.133884496 0.9961546 1.060177951 1.157188711 1.002905575 1 12.91532464 -9.20531841 0.732179658 0.992697002 1.105374788 0.367758265 0.054734835 0.786144859 0.683344308 0.053760285 0.011815375 6.23E-10 9.20531841 0.112677786 KGDVVHCWYTGTLQDGTVFDTNIQTS(ph)AK ddPTM_HeLa_Curcumin_4h_R1 1 KGDVVHCWYTGTLQDGTVFDTNIQTSAK 28 1 Q00688 Q00688 FKBP3 Peptidyl-prolyl cis-trans isomerase FKBP3 1 0 KGDVVHCWYTGTLQDGTVFDT(0.001)NIQT(0.104)S(0.895)AK 127.76 2.91E-10 4877300 897.91 856.43 855.02 608.49 1014.7 1550.4 930.59 555.94 1163.2 1059.5 TRUE FALSE FALSE 826.839476 930.455993 886.7077934 605.9722296 1002.600365 1228.829563 956.6998508 725.4435468 1035.59987 1096.317546 0.754197065 0.8487103 0.808805621 0.552734225 0.914516391 1.120870105 0.87264849 0.661709328 0.944616707 1 10.09845002 -9.431215857 1.132620267 1.001110776 0.817771506 0.154991588 0.143634686 0.72796161 1.654125627 0.105883609 0.025911466 3.70E-10 9.431215857 -0.183339269 KGEDFVK(ac)TLK ddPTM_HeLa_Curcumin_4h_R1 1 KGEDFVKTLK 10 2 P40926;P40926-2;G3XAL0 P40926 MDH2 "Malate dehydrogenase, mitochondrial;Malate dehydrogenase" 0 1 KGEDFVK(1)TLK 91.313 0.0044431 2542800 3629.8 2897.5 3160 3536.6 3920.8 5419.9 3514.5 3508.6 3590.7 3208.1 FALSE TRUE FALSE 3342.4975 3147.946989 3277.11238 3521.966486 3874.047021 4295.751645 3613.107411 4578.355988 3196.809193 3319.581236 1.00690336 0.948296416 0.987206562 1.060967103 1.167028834 1.294064323 1.088422652 1.379196851 0.963015804 1 11.69678554 -5.754070801 2.177013548 0.997521806 1.238770583 0.741352476 0.070805109 0.111325099 1.07567602 0.009390572 0.020430897 1.76E-06 5.754070801 0.241248777 KGEFETGFEK ddPTM_HeLa_Curcumin_4h_R1 2 KGEFETGFEK 10 1 H3BR35;P15170;P15170-2;P15170-3;Q8IYD1 H3BR35 GSPT1;GSPT2 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A;Eukaryotic peptide chain release factor GTP-binding subunit ERF3B 0 0 ; ; 118.28 0.00091858 9261400 6383.2 5227.1 5274.3 5437.3 5491.8 5923.1 4423.2 4551.7 5837.6 5139.4 FALSE FALSE TRUE 5877.962984 5678.907232 5469.770198 5414.801893 5426.313872 4694.582293 4547.303088 5939.492377 5197.229885 5317.993767 1.10529708 1.06786647 1.028540167 1.018203881 1.020368603 0.882773184 0.855078679 1.116867119 0.977291458 1 12.37666637 -5.453025752 5.100877681 1.047752556 0.941951509 0.178613039 0.073432729 0.20732179 10.18479579 0.010354919 0.023361251 3.52E-06 5.453025752 -0.105801047 KGEIFELK ddPTM_HeLa_Curcumin_4h_R1 2 KGEIFELK 8 1 P63010-2;A0A087WYD1;A0A087X253;A0A087WU93;P63010;A0A087WZQ6;K7EKZ5;C9J1E7;K7ERB2;A0A087WXS3;K7EJX1;Q10567-4;Q10567-3;Q10567-2;Q10567;K7EN71 P63010-2 AP2B1;AP1B1 AP-2 complex subunit beta;AP-1 complex subunit beta-1 0 0 ; ; 103.7 0.0028775 3702600 3985.1 2965.9 3504 3595.7 3033.6 4814.5 3017.3 2749.9 3450.8 3274.9 FALSE FALSE TRUE 3669.67513 3222.25918 3633.861322 3580.821946 2997.426301 3815.918429 3101.957317 3588.331851 3072.255873 3388.702531 1.082914507 0.950882868 1.072345917 1.056694093 0.884535091 1.12607064 0.915382005 1.058910252 0.906617163 1 11.72651728 KGEQGGPPPKAS(ph)PSTAGETPSGVK ddPTM_HeLa_Curcumin_4h_R1 2 KGEQGGPPPKASPSTAGETPSGVK 24 2 A0A087WW69;F8W8L6;A0A087WTA5;E7ERK9;Q9UI10-3;Q9UI10;Q9UI10-2 A0A087WW69 EIF2B4 Translation initiation factor eIF-2B subunit delta 1 0 KGEQGGPPPKAS(0.74)PS(0.098)T(0.098)AGET(0.061)PS(0.003)GVK;KGEQGGPPPKAS(0.754)PS(0.063)T(0.024)AGET(0.144)PS(0.015)GVK ; 56.681 0.0024609 91263000 11268.3 8627.2 10683 10629.7 10740.9 12289.7 7842.2 6389.8 10862.3 10103.8 TRUE FALSE FALSE 10376.40216 9372.896726 11078.92138 10585.71712 10612.82178 9740.677687 8062.231026 8338.020605 9670.732866 10454.9063 0.992491168 0.896507004 1.059686339 1.012511907 1.015104438 0.931684839 0.771143308 0.79752227 0.924994695 1 13.35189251 -4.884667051 3.420996189 0.995486835 0.782417208 0.752911862 0.045170549 0.064798987 1.462610427 0.005313103 0.018664365 1.30E-05 4.884667051 -0.213069627 KGESGQSWPR ddPTM_HeLa_Curcumin_4h_R1 1 KGESGQSWPR 10 1 A0A087WYT3;Q15185-4;Q15185;Q15185-3;B4DDC6 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 0 0 103.88 0.0020663 6163700 2697.2 2020.9 2225 2664.1 2312.7 3334.6 2267.2 2195.6 2412.6 2326 FALSE FALSE TRUE 2483.713774 2195.577591 2307.460457 2653.07666 2285.122563 2642.966371 2330.81153 2865.028333 2147.943816 2406.828327 1.031944716 0.912228582 0.958714185 1.10231238 0.949433135 1.098111711 0.968416195 1.190375026 0.892437484 1 11.23291753 -4.253308906 24.61293908 1.00939089 1.190375138 0.40521942 0.069327667 531.0431537 1607551.859 0.00741034 0.109942904 5.58E-05 4.253308906 0.180984248 KGGEFDEFVNDDT(ph)DDDLPISK ddPTM_HeLa_Curcumin_4h_R1 2 KGGEFDEFVNDDTDDDLPISK 21 1 Q6PD62 Q6PD62 CTR9 RNA polymerase-associated protein CTR9 homolog 1 0 KGGEFDEFVNDDT(0.999)DDDLPIS(0.001)K;KGGEFDEFVNDDT(1)DDDLPISK ; 117.08 6.69E-06 568120000 15829.7 12976.3 12408.2 13708.7 14189.7 15808 13010.9 11538 16409 13677.1 TRUE FALSE FALSE 14576.76254 14097.91355 12868.05881 13651.97703 14020.4971 12529.24261 13375.95084 15055.88309 14608.97375 14152.37821 1.029986786 0.996151554 0.90925063 0.964641902 0.990681346 0.885310046 0.945138028 1.063841205 1.032262814 1 13.78875689 -6.986083036 24.34070683 1.014102995 0.956990111 0.263060288 0.045770444 173.6701301 303746.7392 0.0071279 0.009365504 1.03E-07 6.986083036 -0.057112883 KGHAVGDIPGVR ddPTM_HeLa_Curcumin_4h_R1 1 KGHAVGDIPGVR 12 1 D6RD47;P62266 D6RD47 RPS23 40S ribosomal protein S23 0 0 51.013 0.013006 4973000 5176.7 4182.9 4621.5 4764 3896.4 5902.2 3656.9 3609 5733 4635.9 FALSE FALSE TRUE 4766.958733 4544.451237 4792.776855 4744.28783 3849.937975 4678.017188 3759.502772 4709.367486 5104.104243 4796.99718 0.993738073 0.947353327 0.999120215 0.989012012 0.802572491 0.975196985 0.78372003 0.981732386 1.064020689 1 12.22791588 -5.851794787 10.79979534 0.992616582 0.884963526 0.421492915 0.064649912 0.246585738 27.65606324 0.007680791 0.013932528 1.41E-06 5.851794787 -0.107653056 KGLPLGSAVSS(ph)PVLFS(ph)PVGR ddPTM_HeLa_Curcumin_4h_R1 1 KGLPLGSAVSSPVLFSPVGR 20 1 Q8WUM0 Q8WUM0 NUP133 Nuclear pore complex protein Nup133 2 0 KGLPLGS(0.01)AVS(0.522)S(0.619)PVLFS(0.849)PVGR 97.388 0.0002905 38406000 6612.4 4594.5 4903.3 5739.2 5302.1 8396.7 6973.9 3005.3 6360.4 5036.6 TRUE FALSE FALSE 6089.021563 4991.628107 5085.020611 5715.452711 5238.87592 6655.12977 7169.568865 3921.602135 5662.680033 5211.621475 1.168354531 0.957787923 0.97570797 1.096674564 1.005229552 1.276978729 1.375688718 0.752472557 1.086548603 1 12.34751659 -5.287798029 24.61141679 1.06089908 1.15911095 0.050329441 0.162583896 1263.714175 1179945.349 0.022458148 0.050233674 5.15E-06 5.287798029 0.09821187 KGLPLGSAVSSPVLFS(ph)PVGR ddPTM_HeLa_Curcumin_4h_R1 2 KGLPLGSAVSSPVLFSPVGR 20 1 Q8WUM0 Q8WUM0 NUP133 Nuclear pore complex protein Nup133 1 0 KGLPLGSAVS(0.009)S(0.232)PVLFS(0.76)PVGR;KGLPLGSAVS(0.002)S(0.132)PVLFS(0.866)PVGR ; 131.62 4.19E-05 66302000 11207.4 8550.8 9906.7 10013.1 9157.1 11617 7858.18 6398.47 11224.9 10392.7 TRUE FALSE FALSE 10320.32246 9289.89305 10273.85102 9971.668445 9047.907563 9207.503249 8078.659382 8349.334048 9993.556553 10753.84555 0.959686692 0.86386707 0.955365313 0.927265358 0.841364842 0.856205643 0.751234462 0.776404497 0.929300733 1 13.39256504 -1.829237006 0.206087064 1.012850313 0.012399101 0.730863488 0.040304452 9.170990751 0.144049554 0.029985891 2.806274884 0.014817093 1.829237006 -1.000451211 KGLTPSQIGVILR ddPTM_HeLa_Curcumin_4h_R1 2 KGLTPSQIGVILR 13 1 P62277;J3KMX5 P62277 RPS13 40S ribosomal protein S13 0 0 ; ; 108.32 0.00068891 0 3127.8 2779.3 2509.1 2520.6 2305.1 3839.4 2867.9 2549.3 2639 2465.1 FALSE FALSE TRUE 2880.23133 3019.530308 2602.089453 2510.170425 2277.613188 3043.065161 2948.365555 3326.569834 2349.508302 2550.762042 1.129165043 1.183775773 1.020122383 0.984086475 0.892914804 1.19300237 1.155876365 1.304147459 0.921100543 1 11.3167126 -4.704293345 1.870893191 1.054272647 1.279256947 0.445558189 0.094587293 0.32125417 1.949385295 0.013406108 0.09299284 1.98E-05 4.704293345 0.224984301 KGLVGPELHDR ddPTM_HeLa_Curcumin_4h_R1 3 KGLVGPELHDR 11 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ;; ;; 80.979 0.0035941 20238800 11746.9 9286.7 9961.7 10772.9 10370 13815.2 10738.9 8936.5 12688.6 11343.1 FALSE FALSE TRUE 10817.12047 10089.40097 10330.88937 10728.32459 10246.34452 10949.77179 11040.20463 11661.19771 11296.69233 11737.27188 0.92160432 0.859603583 0.880178075 0.914039029 0.872974966 0.932906037 0.940610795 0.993518582 0.962463206 1 13.5188095 -8.809745944 0.903682216 0.995431876 0.912703086 0.31532599 0.037986757 0.397360468 0.63760102 0.01867853 0.007795356 1.55E-09 8.809745944 -0.08272879 KGNAEGS(ph)S(ph)DEEGKLVIDEPAK ddPTM_HeLa_Curcumin_4h_R1 1 KGNAEGSSDEEGKLVIDEPAK 21 2 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 2 0 KGNAEGS(1)S(1)DEEGKLVIDEPAK 81.878 0.00078002 18972000 3940 3539.1 4409.1 3245.2 5145.5 3802.8 4180.8 3844.2 3016.3 3538.4 TRUE FALSE FALSE 3628.144843 3845.004034 4572.505125 3231.772222 5084.143273 3014.056414 4298.101996 5016.278883 2685.419436 3661.359137 0.990928425 1.050157576 1.248854579 0.882670096 1.388594531 0.823206984 1.173908878 1.370059231 0.733448792 1 11.83816358 -1.111761427 0.949394314 1.024202772 198.3757959 0.250073042 0.184718581 831.6952858 1.759134907 0.022314408 355981.058 0.077310516 1.111761427 197.3515931 KGNS(ph)PNSEPPTPK ddPTM_HeLa_Curcumin_4h_R1 2 KGNSPNSEPPTPK 13 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 0 KGNS(0.985)PNS(0.015)EPPTPK;KGNS(0.979)PNS(0.021)EPPTPK ; 86.005 0.0076425 133947000 10458.3 9112.7 10676 11601.7 11112.8 12799.3 9278.4 7521.4 12504.4 10527.6 TRUE FALSE FALSE 9630.514519 9900.361183 11071.66195 11553.69524 10980.28712 10144.5809 9538.726932 9814.640236 11132.6986 10893.43332 0.884066046 0.908837544 1.016361108 1.060611003 1.007973042 0.931256529 0.87564009 0.900968496 1.021964176 1 13.4111711 -4.95031632 5.204547809 0.959607959 0.889963548 0.267380442 0.054702885 0.271562596 16.26343748 0.009193366 0.028371597 1.12E-05 4.95031632 -0.069644412 KGNSPNS(ph)EPPTPK ddPTM_HeLa_Curcumin_4h_R1 3 KGNSPNSEPPTPK 13 1 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 0 KGNS(0.005)PNS(0.927)EPPT(0.069)PK;KGNS(0.02)PNS(0.98)EPPTPK;KGNS(0.358)PNS(0.642)EPPT(0.001)PK ;; 123.76 0.0010124 73555300 14823.9 12787.3 13769.7 13722.9 13848.3 17159.6 14723.6 17254.5 16834.1 13297.7 TRUE FALSE FALSE 13650.57267 13892.57723 14280.0172 13666.11828 13683.16807 13600.50553 15136.70459 22515.31762 14987.44135 13759.79409 0.992062279 1.009650082 1.037807478 0.993192063 0.994431165 0.988423624 1.100067668 1.636312105 1.089219886 1 13.74817126 -4.25238814 2.882803183 0.999599296 1.756009517 0.971625766 0.031688891 0.02238013 0.255344877 0.002155406 0.039736655 5.59E-05 4.25238814 0.756410221 KGPAAPPPT(ph)PVKPPR ddPTM_HeLa_Curcumin_4h_R1 2 KGPAAPPPTPVKPPR 15 2 E9PIE3;Q969G5 E9PIE3 PRKCDBP Protein kinase C delta-binding protein 1 0 KGPAAPPPT(1)PVKPPR;KGPAAPPPT(1)PVKPPR ; 71.637 0.011757 241180000 5406 5172.3 5314.7 5337.8 5781.5 8297.5 9605.7 4063.4 6516.3 5887.7 TRUE FALSE FALSE 4978.109396 5619.370565 5511.667457 5315.713598 5712.559389 6576.504968 9875.21009 5302.311954 5801.478193 6092.297137 0.817115332 0.922373029 0.904694458 0.872530259 0.937669201 1.079478696 1.620933757 0.87033049 0.952264485 1 12.57277059 -4.997427124 24.98613165 0.913641146 1.271775683 0.366647566 0.174287174 52.67108092 511480.9451 0.022002535 0.065451701 1.01E-05 4.997427124 0.358134537 KGPGLAVQSGDK(ac)TK ddPTM_HeLa_Curcumin_4h_R1 1 KGPGLAVQSGDKTK 14 2 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 0 1 KGPGLAVQSGDK(1)TK 118.2 0.00014391 17575000 9213.3 8000.1 8616.8 8210.4 8683.3 11747 9978.7 9950.8 8930.4 7616.4 FALSE TRUE FALSE 8484.057583 8691.592996 8936.146188 8176.42754 8579.757319 9310.539784 10258.67547 12984.75311 7950.757463 7881.069333 1.076510969 1.102844377 1.133874835 1.03747692 1.088653957 1.181380266 1.301685727 1.647587727 1.008842471 1 12.94417568 -1 0.644858851 1.044283436 53.62738382 0.956507305 0.038324225 30.25986434 0.184517411 0.00766156 2273.76746 0.1 1 52.58310038 KGPGQPSS(ph)PQRLDR ddPTM_HeLa_Curcumin_4h_R1 1 KGPGQPSSPQRLDR 14 2 O95400 O95400 CD2BP2 CD2 antigen cytoplasmic tail-binding protein 2 1 0 KGPGQPS(0.483)S(0.517)PQRLDR 74.726 0.018787 45218000 4028.1 3296.2 3315.5 3246.8 3157.9 4799 3584.5 3591.2 4185.7 3567.4 TRUE FALSE FALSE 3709.271635 3581.10884 3438.375347 3233.365602 3120.244105 3803.633304 3685.071423 4686.140348 3726.539182 3691.366884 1.004850439 0.970130836 0.931463995 0.875926372 0.845281491 1.030413238 0.998294545 1.269486479 1.009528258 1 11.84993942 -4.199691276 2.761297829 0.976535969 1.353154291 0.703915465 0.059150655 0.296409765 2.603275121 0.009247218 0.269199677 6.31E-05 4.199691276 0.376618323 KGPPTQELDRDS(ph)EEEEEEDDEDGEDEEEVPK ddPTM_HeLa_Curcumin_4h_R1 1 KGPPTQELDRDSEEEEEEDDEDGEDEEEVPK 31 2 Q14687-2;Q14687-3;Q14687;H7C3B5;H0Y613 Q14687-2 GSE1 Genetic suppressor element 1 1 0 KGPPT(0.144)QELDRDS(0.856)EEEEEEDDEDGEDEEEVPK 44.712 0.0075653 31963000 2026.9 1778.2 1893.9 2393 2125.9 1842.7 1742.4 1232.3 2183.3 1863.1 TRUE FALSE FALSE 1866.468726 1931.899684 1964.0896 2383.0984 2100.550031 1460.503248 1791.287055 1608.022597 1943.797452 1927.842586 0.968164486 1.002104476 1.018801853 1.236147815 1.089585864 0.757584286 0.929166659 0.834104718 1.008276021 1 10.91277154 -5.26480917 24.99330559 1.013921825 0.849173365 0.528831821 0.085209679 219.4262604 1627464.341 0.013252691 0.030783737 5.43E-06 5.26480917 -0.164748461 KGRS(ph)PDELPSAGGDGGK ddPTM_HeLa_Curcumin_4h_R1 2 KGRSPDELPSAGGDGGK 17 2 B4E2I7;A0A2R8Y5N1;A0A140T8Z0;A0A0G2JH68;O60610-2;O60610-3;O60610 B4E2I7 DIAPH1 Protein diaphanous homolog 1 1 0 KGRS(1)PDELPSAGGDGGK;KGRS(1)PDELPSAGGDGGK ; 108.25 0.00093405 15231000 5447.9 4329.8 4023.6 4445.1 4081.1 5420.2 4008.7 5046.1 5817.2 4699.1 TRUE FALSE FALSE 5016.692966 4704.048619 4172.718156 4426.707354 4032.435548 4295.989422 4121.173333 6584.632661 5179.067714 4862.393375 1.03173326 0.967434812 0.858161369 0.910396797 0.829310843 0.883513342 0.847560659 1.354195795 1.065127256 1 12.2474509 -7.004571145 23.85632073 1.014174572 0.93107476 0.054676485 0.144039349 231.9590773 1210582.61 0.021869741 0.028310293 9.90E-08 7.004571145 -0.083099812 KGS(ph)DALRPPVPQGEDEVPK ddPTM_HeLa_Curcumin_4h_R1 1 KGSDALRPPVPQGEDEVPK 19 2 Q8N3D4;E9PIH6 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 0 KGS(1)DALRPPVPQGEDEVPK 61.04 0.01519 16059000 1406.6 1514.6 1377.7 1286.8 1382.1 1860.9 1538.7 1019.8 1442.3 1339.9 TRUE FALSE FALSE 1295.266126 1645.515275 1428.758774 1281.475563 1365.61936 1474.928363 1581.871781 1330.732325 1284.083298 1386.461425 0.934224424 1.186845335 1.030507411 0.924277834 0.98496744 1.063807717 1.14094179 0.959804796 0.926158691 1 10.43719176 KGS(ph)DDAPYSPTAR ddPTM_HeLa_Curcumin_4h_R1 1 KGSDDAPYSPTAR 13 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 0 KGS(0.925)DDAPYS(0.075)PTAR 97.2 0.013354 3933300 1263.9 956.61 1194.3 1362.8 1332.4 1310 1321.7 1355.7 1669.8 1054.7 TRUE FALSE FALSE 1163.860981 1039.295106 1238.561809 1357.161095 1316.512 1038.291233 1358.783345 1769.046689 1486.627118 1091.350746 1.066440817 0.95230164 1.134888864 1.24356088 1.206314289 0.951381796 1.245047341 1.62096988 1.362190041 1 10.09189913 -1.274969288 0.929902441 1.050582693 199.9999999 0.493311783 0.14021708 228.491952 0.74577925 0.016231852 96174.32384 0.053092199 1.274969288 198.9494172 KGS(ph)GS(ph)EQEGEDEEGGER ddPTM_HeLa_Curcumin_4h_R1 3 KGSGSEQEGEDEEGGER 17 1 Q6PD62 Q6PD62 CTR9 RNA polymerase-associated protein CTR9 homolog 2 0 KGS(1)GS(1)EQEGEDEEGGER;KGS(1)GS(1)EQEGEDEEGGER;KGS(1)GS(1)EQEGEDEEGGER ;; 179.9 1.29E-05 52399200 8624.7 7694 7457.9 8070.1 7899.7 9250.8 7400.5 6801.2 8490.9 7761 TRUE FALSE FALSE 7942.045894 8359.035076 7734.296335 8036.708064 7805.501237 7332.079802 7608.138113 8874.854571 7559.469513 8030.694172 0.988961318 1.040885744 0.963091878 1.000748863 0.971958472 0.913006976 0.947382374 1.105116741 0.941322051 1 12.97130898 KGS(ph)GS(ph)EQEGEDEEGGERK ddPTM_HeLa_Curcumin_4h_R1 1 KGSGSEQEGEDEEGGERK 18 2 Q6PD62 Q6PD62 CTR9 RNA polymerase-associated protein CTR9 homolog 2 0 KGS(1)GS(1)EQEGEDEEGGERK 90.561 0.00196 13132000 9247.7 7162.3 7659.1 7813 7667.9 8176.5 6833.5 5868.4 8464.3 7715.7 TRUE FALSE FALSE 8515.734787 7781.377297 7942.952984 7780.671876 7576.465301 6480.601732 7025.229619 7657.648145 7535.787467 7983.820001 1.066624095 0.974643378 0.99488127 0.974555022 0.948977469 0.811716914 0.879933367 0.959145891 0.943882435 1 12.96286348 -5.925306692 1.278824821 1.027312079 0.884443862 0.42188598 0.049965215 0.207719633 0.67594473 0.00752143 0.017840301 1.19E-06 5.925306692 -0.142868217 KGS(ph)ITEYTAAEEK ddPTM_HeLa_Curcumin_4h_R1 2 KGSITEYTAAEEK 13 1 J3KN59;Q12982;Q12982-2 J3KN59 BNIP2 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 1 0 KGS(0.644)IT(0.304)EYT(0.052)AAEEK;KGS(0.717)IT(0.199)EY(0.002)T(0.082)AAEEK ; 99.747 0.011296 89237000 9420.3 7419.4 10301.7 9512.5 10459.8 10843.6 9250.8 8215.3 8940.2 8014.9 TRUE FALSE FALSE 8674.673315 8060.699876 10683.49006 9473.139795 10335.07372 8594.515127 9510.352551 10720.10715 7959.482427 8293.417178 1.045970934 0.971939516 1.288189155 1.142248074 1.246177962 1.036305656 1.146735097 1.292604354 0.959734963 1 13.01775095 -6.774344022 24.99997025 1.018582377 1.183102175 0.609362144 0.076346225 125.5206497 243168.8804 0.011497831 0.015164472 1.68E-07 6.774344022 0.164519798 KGS(ph)SSSVCSVASSSDISLGSTK ddPTM_HeLa_Curcumin_4h_R1 1 KGSSSSVCSVASSSDISLGSTK 22 1 A0A087X2H1;Q9ULT8;H0YJP0 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 0 KGS(0.282)S(0.282)S(0.282)S(0.063)VCS(0.09)VASSSDISLGSTK 84.324 0.00030006 12834000 1469.8 1218.9 1508.6 1286.6 1599.9 1660.7 1569.7 2031.3 1331.7 1440.7 TRUE FALSE FALSE 1353.463779 1324.256285 1564.510043 1281.27639 1580.822237 1316.2521 1613.741557 2650.634019 1185.615842 1490.764218 0.907899293 0.888306996 1.04946847 0.859476217 1.060410639 0.882937814 1.082492817 1.778037055 0.795307419 1 10.54183638 -4.267027773 3.216059954 0.954121736 1.891398035 0.902415245 0.082961086 0.053970436 0.878448386 0.008645166 0.125186584 5.41E-05 4.267027773 0.937276299 KGSLSSVTPS(ph)PTPENEKQPWSDFAVLNGGK ddPTM_HeLa_Curcumin_4h_R1 1 KGSLSSVTPSPTPENEKQPWSDFAVLNGGK 30 2 Q92870;Q92870-4 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 0 KGS(0.063)LS(0.072)S(0.072)VT(0.241)PS(0.444)PT(0.089)PENEKQPWS(0.02)DFAVLNGGK 44.596 0.0083572 15541000 1144.2 1041.8 955.17 1126 650.89 523.85 750.34 375.32 961.97 1396.7 TRUE FALSE FALSE 1053.635363 1131.84855 990.5694405 1121.34091 643.1285619 415.197605 771.392521 489.7533402 856.4442977 1445.235221 0.729040745 0.783158709 0.685403612 0.77588817 0.444999231 0.287287217 0.53374877 0.338874484 0.592598551 1 10.4970886 -5.482059778 0.198423626 1.063233856 2.42E-17 0.45776607 0.154452529 2.672639532 0.16608626 0.180537088 0.76454063 3.30E-06 5.482059778 -1.063233856 KGSSSQAPASK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 KGSSSQAPASKK 12 2 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 0 1 KGSSSQAPASK(1)K 79.744 0.010333 602510 898.62 2697.5 766.34 495.44 462.84 894.71 556.79 522.33 422.25 653.31 FALSE TRUE FALSE 827.4932788 2930.65988 794.7412345 493.3900006 457.3209353 709.1370605 572.4120289 681.5860125 375.9302314 676.0124739 1.224079896 4.335215685 1.175631021 0.729853397 0.676497776 1.048999964 0.846747732 1.008244727 0.556099548 1 9.400906057 -6.518862593 24.99171336 1.417855345 0.870437905 0.123900578 0.978497805 409.368268 2547420.416 0.158320417 0.226944954 3.03E-07 6.518862593 -0.547417441 KGTENGVNGTLTSNVADS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 KGTENGVNGTLTSNVADSPR 20 1 G3XAN4;Q15629-2;Q15629 G3XAN4 TRAM1 Translocating chain-associated membrane protein 1 1 0 KGTENGVNGTLT(0.002)S(0.006)NVADS(0.993)PR;KGTENGVNGTLT(0.005)S(0.013)NVADS(0.982)PR ; 113.23 8.63E-05 20611000 3329.5 3480.5 3463.4 5957.7 3661 5304.1 1947.57 1295.77 6829.8 4619.1 TRUE FALSE FALSE 3065.966562 3781.338911 3591.756651 5933.048616 3617.344966 4203.96987 2002.213573 1690.844308 6080.588027 4779.613381 0.641467482 0.791139075 0.751474306 1.241323961 0.756827944 0.879562746 0.418907015 0.353761732 1.272192444 1 12.22267821 -4.735084072 6.323026961 0.845705 0.378431709 0.490161176 0.206540541 0.102278882 12.99604418 0.025141766 0.092129846 1.84E-05 4.735084072 -0.467273291 KGTVEGFEPADNK ddPTM_HeLa_Curcumin_4h_R1 2 KGTVEGFEPADNK 13 1 H0YLA2;P37108 H0YLA2 SRP14 Signal recognition particle 14 kDa protein 0 0 ; ; 142.95 0.00013082 13080200 12702.7 10384.4 11761.2 12268 11364.2 13822.5 11258.8 10403.2 13941 11589.3 FALSE FALSE TRUE 11697.26789 11281.98126 12197.08042 12217.23827 11228.68934 10955.55769 11574.69163 13575.08779 12411.70718 11992.02731 0.975420384 0.940790158 1.017099119 1.018780057 0.936346211 0.913570108 0.965198905 1.132009412 1.034996574 1 13.54978795 KGVAINFVK ddPTM_HeLa_Curcumin_4h_R1 1 KGVAINFVK 9 1 I3L3H2;P38919 I3L3H2 EIF4A3 "Eukaryotic initiation factor 4A-III;Eukaryotic initiation factor 4A-III, N-terminally processed" 0 0 95.502 0.0028651 0 3500.3 2574.9 3398 2887.9 3184.8 4364.1 3253.6 3332.4 3123.1 3463.6 FALSE FALSE TRUE 3223.247562 2797.462882 3523.932869 2875.950635 3146.82334 3458.936466 3344.887259 4348.43342 2780.503744 3583.959842 0.899353705 0.780550845 0.983251215 0.802450575 0.878029743 0.965115855 0.933293733 1.213304169 0.775818889 1 11.80733876 -4.260104243 5.804806934 0.926802549 1.222191248 0.529685893 0.085320931 0.082463174 12.12840273 0.010734197 0.095539177 5.49E-05 4.260104243 0.295388699 KGVAINMVTEEDK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 KGVAINMVTEEDKR 14 2 P60842 P60842 EIF4A1 Eukaryotic initiation factor 4A-I 0 1 ; KGVAINMVTEEDK(1)R;KGVAINMVTEEDK(1)R 116.87 0.00010444 8875100 5217.4 6805.1 5080.6 5297.3 10218.2 13979.6 9823.4 9946.3 14120.5 5613.1 FALSE TRUE FALSE 4804.437285 7393.302521 5268.891505 5275.381176 10096.35464 11080.07338 10099.01817 12978.88108 12571.51648 5808.154807 0.827188228 1.272917607 0.90715411 0.908271448 1.738306738 1.907675285 1.738765322 2.234596273 2.164459608 1 12.50386419 -5.693672905 3.980451766 0.942989858 1.921950946 0.350557095 0.419363475 0.050491993 1.580941519 0.02393883 0.048832192 2.02E-06 5.693672905 0.978961088 KGVAINMVTEEDKR ddPTM_HeLa_Curcumin_4h_R1 3 KGVAINMVTEEDKR 14 2 P60842 P60842 EIF4A1 Eukaryotic initiation factor 4A-I 0 0 ;; ;; 99.844 0.0016099 48420200 9199.5 7422.5 7210.7 8636 8285.1 9587 7187.9 7317.3 8771.5 8595.1 FALSE FALSE TRUE 8471.349868 8064.067826 7477.934885 8600.26652 8186.305594 7598.548132 7389.573129 9548.311085 7809.288395 8893.779085 0.952502843 0.906708807 0.840805108 0.966997992 0.920452995 0.854366638 0.830869876 1.073594362 0.878061881 1 13.11858085 -7.797229965 1.153403829 0.987985079 0.908077693 0 0.075715741 0.462695424 1.288957875 0.01532822 0.014039773 1.60E-08 7.797229965 -0.079907386 KGVEPSPS(ph)PIKPGDIK ddPTM_HeLa_Curcumin_4h_R1 1 KGVEPSPSPIKPGDIK 16 2 Q92890-3;Q92890;Q92890-1;C9JNP9 Q92890-3 UFD1L Ubiquitin fusion degradation protein 1 homolog 1 0 KGVEPS(0.203)PS(0.797)PIKPGDIK 92.39 0.003527 15408000 879.84 962.79 1065 975.09 1150.2 1407.6 1050.6 402.13 964.34 805.08 TRUE FALSE FALSE 810.1997356 1046.009277 1104.469837 971.0553359 1136.484616 1115.647893 1080.077008 524.7375858 858.5543147 833.0564701 0.972562803 1.255628298 1.325804284 1.165653675 1.364234787 1.339222409 1.296523162 0.629894377 1.030607582 1 9.702270484 -7.265354723 24.18932949 0.98704354 1.216243129 0.159752183 0.201411198 231.7954491 1432050.076 0.03234707 0.037744892 5.43E-08 7.265354723 0.229199589 KGVITVK(ac)DGK ddPTM_HeLa_Curcumin_4h_R1 1 KGVITVKDGK 10 2 P10809;E7EXB4 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 1 KGVITVK(1)DGK 93.839 0.0027281 0 5252 4035.7 4122.4 5149.6 4702.5 7578.9 5550.8 4681.2 5132.3 3960 FALSE TRUE FALSE 4836.298658 4384.527925 4275.17977 5128.29232 4646.425759 6006.950708 5706.540509 6108.47633 4569.29953 4097.609705 1.180273136 1.070020876 1.043335036 1.251532647 1.133935658 1.465964584 1.392651062 1.490741376 1.11511341 1 12.00056686 -1 0.248465572 1.036037171 4.180421012 0.762967368 0.082389373 16.84139929 0.209808708 0.048142029 22.34856495 0.1 1 3.144383841 KGVNLPGAAVDLPAVSEK ddPTM_HeLa_Curcumin_4h_R1 2 KGVNLPGAAVDLPAVSEK 18 1 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BQ34;H3BR70 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 126.07 3.79E-05 18088100 8328.5 8286.1 7905.3 8314.9 8024.9 8950 6914.7 7021 8058.7 8558.7 FALSE FALSE TRUE 7669.290437 9002.313562 8198.277372 8280.495147 7929.208309 7093.669113 7108.707872 9161.670579 7174.680772 8856.114188 0.865988206 1.016508298 0.925719475 0.935003205 0.895337181 0.800991153 0.802689274 1.034502309 0.810138693 1 13.11245811 -5.666950424 3.782058363 0.941004579 0.868709878 0.036133658 0.08291295 0.336645158 9.208856644 0.011386812 0.023522957 2.15E-06 5.666950424 -0.072294702 KGVSASAVPFTPSS(ph)PLLSCSQEGSR ddPTM_HeLa_Curcumin_4h_R1 2 KGVSASAVPFTPSSPLLSCSQEGSR 25 1 J3QRU8;Q9Y2X7;Q9Y2X7-3;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 0 KGVSASAVPFTPS(0.163)S(0.828)PLLS(0.007)CS(0.002)QEGSR;KGVSASAVPFT(0.001)PS(0.266)S(0.693)PLLS(0.027)CS(0.011)QEGS(0.003)R ; 167.17 4.06E-12 67781000 6409.2 4500.2 5663.2 5510.7 5609.4 6785.8 3957 2421.59 6437.7 5455.2 TRUE FALSE FALSE 5901.905057 4889.177235 5873.083174 5487.898184 5542.511569 5378.348588 4068.02277 3159.921643 5731.500416 5644.767794 1.045553205 0.866143199 1.040447258 0.972209732 0.981884777 0.952802451 0.720671411 0.559796569 1.015365136 1 12.46269852 -4.583689581 1.677573546 1.006618015 0.518003271 0.890616019 0.049672955 0.117806571 0.492011175 0.007299488 0.075739378 2.61E-05 4.583689581 -0.488614744 TQLASWS(ph)DPTEETGPVAGILDTETLEK ddPTM_HeLa_Curcumin_4h_R1 1 TQLASWSDPTEETGPVAGILDTETLEK 27 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 T(0.02)QLAS(0.379)WS(0.601)DPTEETGPVAGILDTETLEK 136.88 1.97E-08 66229000 3227.5 2564.3 2857.5 2985.3 2854 4221.1 4113.2 10617 3652 4107.7 TRUE FALSE FALSE 2972.039969 2785.946666 2963.401464 2972.94762 2819.967914 3345.596278 4228.605322 13854.07443 3251.384737 4250.442269 0.699230758 0.655448654 0.69719838 0.6994443 0.663452821 0.787117214 0.994862429 3.259443029 0.764952099 1 12.05339725 -4.259207372 4.074797003 0.801932098 3.475944406 0.980056776 0.106668207 0.031192212 1.101709544 0.020990622 0.244946679 5.51E-05 4.259207372 2.674012308 up KHEAFESDLAAHQDR ddPTM_HeLa_Curcumin_4h_R1 4 KHEAFESDLAAHQDR 15 1 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75;A0A494C1A0;P35609-2;P35609;H7C5W8;A0A494C060;F6THM6 O43707;P12814-4 ACTN4;ACTN1;ACTN2 Alpha-actinin-4;Alpha-actinin-1;Alpha-actinin-2 0 0 ;;; ;;; 106.55 0.000642 33477400 10983.3 6264.3 11978.5 7392.9 17350.4 18882.3 14831.9 14814.1 7791.2 7722.3 FALSE FALSE TRUE 10113.96022 6805.758179 12422.43375 7362.310139 17143.50781 14965.89813 15248.0432 19330.85089 6936.524853 7990.64935 1.265724445 0.851715284 1.554621308 0.921365688 2.145446141 1.872926401 1.908235805 2.41918398 0.868080246 1 12.96409703 -5.756921101 24.9999308 1.12859339 2.058467243 0.802038993 0.244742765 36.03423729 199377.2687 0.032223366 0.06274117 1.75E-06 5.756921101 0.929873853 KHEAFETDFTVHKDR ddPTM_HeLa_Curcumin_4h_R1 1 KHEAFETDFTVHKDR 15 2 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 32.734 0.020384 17476000 5662.1 3604.2 4582.9 4585 4578.7 7064.4 5283.8 4656.8 4699.1 4751.5 FALSE FALSE TRUE 5213.93881 3915.730988 4752.746306 4566.028485 4524.101993 5599.163808 5432.049207 6076.636883 4183.620487 4916.614271 1.060473432 0.796428349 0.966670567 0.928693656 0.920166143 1.138825114 1.104835341 1.235939317 0.85091493 1 12.26344946 -5.155442621 5.958121002 0.992750247 1.158203767 0.503100044 0.090773052 0.175853548 8.388857626 0.012442551 0.03231481 6.99E-06 5.155442621 0.165453521 KHEAIETDIAAYEER ddPTM_HeLa_Curcumin_4h_R1 1 KHEAIETDIAAYEER 15 1 A0A087WUZ3;Q01082;Q01082-2;F8W6C1;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 86.548 0.0030413 9341300 5764.6 3669.3 5505 4836.3 5848 7237.6 5573.1 4885.4 5448.4 5256.4 FALSE FALSE TRUE 5308.325827 3986.457942 5709.020143 4816.288672 5778.266419 5736.440175 5729.466187 6374.93597 4850.724151 5439.059509 0.975963918 0.732931481 1.049633697 0.885500272 1.062364993 1.054675016 1.053392811 1.172065862 0.891831417 1 12.4091415 -4.614743507 0.915791915 0.967647536 1.197364941 0.385122602 0.091792768 1.208075215 1.065852072 0.01379144 0.243028413 2.43E-05 4.614743507 0.229717405 KHLEINPDHPIVETLR ddPTM_HeLa_Curcumin_4h_R1 3 KHLEINPDHPIVETLR 16 1 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 0 ;; ;; 112.24 0.00036101 155157000 20785.4 16201.1 17535.4 17945.7 15913.4 23077.3 16803 16877.5 20864.6 17928 FALSE FALSE TRUE 19140.21366 17601.45089 18185.27735 17871.44545 15723.6431 18290.80785 17274.44696 22023.37206 18575.80558 18550.99667 1.031762013 0.948814299 0.980285732 0.963368479 0.847590207 0.985974402 0.931187001 1.187179991 1.001337336 1 14.17920908 -7.265641574 24.67128596 1.014998728 0.970831007 0.028914647 0.080696077 685.6302207 4025362.631 0.012978343 0.015135615 5.42E-08 7.265641574 -0.044167721 KHLEINPDHSIIETLR ddPTM_HeLa_Curcumin_4h_R1 3 KHLEINPDHSIIETLR 16 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 ;; ;; 129.29 0.00011682 92130300 15409.5 12766.2 13215.5 13207.6 12634 19569.4 14250.9 13555.9 17056.4 15041.3 FALSE FALSE TRUE 14189.82181 13869.65344 13705.27806 13152.95045 12483.3478 15510.48585 14650.7419 17689.03151 15185.35559 15563.98406 0.911708838 0.891137731 0.880576465 0.845088918 0.802066345 0.996562692 0.941323369 1.136536214 0.97567278 1 13.92592379 -4.025653041 1.928988569 0.929786073 1.322731994 0.515379816 0.062813743 1.417522469 3.128090898 0.010438557 1.227934053 9.43E-05 4.025653041 0.392945921 KHPDASVNFSEFSK ddPTM_HeLa_Curcumin_4h_R1 1 KHPDASVNFSEFSK 14 1 Q5T7C4;P09429 Q5T7C4 HMGB1 High mobility group protein B1 0 0 30.998 0.020333 5945900 6323.2 5164.4 5110.6 5602.2 7099.5 8431.7 6209.7 5871.5 6331.4 6517.9 FALSE FALSE TRUE 5822.712048 5610.787724 5300.003332 5579.019581 7014.843099 6682.870375 6383.927469 7661.693321 5636.86126 6744.39654 0.863340703 0.831918422 0.785838036 0.82720812 1.040099445 0.99087744 0.946552806 1.136008726 0.835784377 1 12.71947365 -1.000001482 0.773522756 0.913493904 45.84164401 0.4436998 0.080866298 376.6814099 1.384217589 0.014924635 29597.7898 0.099999659 1.000001482 44.9281501 IISIFS(ph)GTEK ddPTM_HeLa_Curcumin_4h_R1 1 IISIFSGTEK 10 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 0 IIS(0.015)IFS(0.885)GT(0.1)EK 154.67 0.00064529 46943000 2343.7 2076.4 2114.8 2305.4 2628.4 3400.2 4713.5 32299 0 1956.9 TRUE FALSE FALSE 2158.193672 2255.874764 2193.176348 2295.860866 2597.058047 2694.960192 4845.748124 42146.81641 0 2024.902129 1.065826165 1.114066073 1.083102396 1.133813251 1.282559788 1.330908864 2.393077697 20.81424865 0 1 10.98363646 -4.259174108 4.326925273 1.099990258 22.30970576 0.996230682 0.363609421 0.004761222 0.209181798 0.028157146 0.310130296 5.51E-05 4.259174108 21.2097155 up KHSEEAEFTPPLKCS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 KHSEEAEFTPPLKCSPK 17 2 Q3B726 Q3B726 TWISTNB DNA-directed RNA polymerase I subunit RPA43 1 0 KHSEEAEFT(0.003)PPLKCS(0.996)PK;KHSEEAEFT(0.001)PPLKCS(0.999)PK ; 65.477 0.0072859 81918000 7572.1 6127.8 6655.3 7880.9 6727.3 7245.7 4783.9 3217.8 7606.1 6506.7 TRUE FALSE FALSE 6972.760295 6657.459727 6901.951273 7848.290924 6647.081341 5742.860144 4918.123359 4198.892407 6771.72986 6732.807341 1.035639361 0.988808886 1.025122348 1.165678821 0.987267421 0.852966653 0.730471423 0.6236466 1.005781024 1 12.71699247 -4.897784555 1.721219738 1.026123755 0.637697152 0.892476237 0.049880871 0.094656012 0.510335671 0.007563388 0.040252219 1.27E-05 4.897784555 -0.388426603 KHVTTAEGTPGTTDQEGPPPDGPPEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 KHVTTAEGTPGTTDQEGPPPDGPPEKR 27 2 O14497;O14497-2;H0Y488;A0A1B0GTU5;O14497-3 O14497 ARID1A AT-rich interactive domain-containing protein 1A 0 1 ; KHVTTAEGTPGTTDQEGPPPDGPPEK(1)R;KHVTTAEGTPGTTDQEGPPPDGPPEK(1)R 85.013 6.77E-05 5108400 1258.76 1126.86 1002.83 679.7 1399.02 2273.9 1006.85 563.01 1312.73 943.69 FALSE TRUE FALSE 1159.127818 1224.260757 1039.995762 676.8875815 1382.3376 1802.267508 1035.099501 734.6691572 1168.726803 976.4831573 1.187043329 1.253744878 1.065042192 0.693189203 1.415628718 1.845671883 1.060028013 0.752362344 1.196873489 1 9.93145135 KIAELEEEQSQGST(ph)TNSDWMK ddPTM_HeLa_Curcumin_4h_R1 1 KIAELEEEQSQGSTTNSDWMK 21 1 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 KIAELEEEQSQGS(0.003)T(0.571)T(0.353)NS(0.073)DWMK 127.32 1.19E-05 47841000 3236.4 2376 2717 2524.5 2405.9 3339.3 2950.1 2418.8 3162.4 2638.5 TRUE FALSE FALSE 2980.235525 2581.370853 2817.69441 2514.054288 2377.211214 2646.691538 3032.871866 3156.280985 2815.492632 2730.187679 1.091586321 0.945492089 1.032051544 0.920835702 0.87071348 0.969417436 1.110865707 1.156067405 1.031245088 1 11.41478441 -4.618422653 5.08364631 1.011474614 1.145582011 0.422246716 0.064623237 0.183710326 7.515591534 0.010895051 0.043729899 2.41E-05 4.618422653 0.134107397 KIAELEEEQSQGSTT(ph)NSDWMK ddPTM_HeLa_Curcumin_4h_R1 1 KIAELEEEQSQGSTTNSDWMK 21 1 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 KIAELEEEQSQGS(0.007)T(0.022)T(0.67)NS(0.301)DWMK 102.98 5.91E-05 46900000 6049.9 4767 5820.7 5498.8 5007.8 6851.3 5530.9 4987.5 6595.7 5297.1 TRUE FALSE FALSE 5571.044031 5179.038239 6036.420262 5476.047423 4948.085256 5430.26315 5686.082168 6508.16579 5872.168212 5481.173831 1.01639616 0.944877575 1.101300643 0.999064724 0.902741896 0.990711719 1.037384025 1.187367157 1.07133406 1 12.42026917 -4.277381086 2.959859227 1.001225442 1.214937568 0.517104456 0.05310423 0.199163512 2.559046228 0.006523997 0.098669011 5.28E-05 4.277381086 0.213712126 KICTLPSPPS(ph)PLASLAPVADSSTR ddPTM_HeLa_Curcumin_4h_R1 2 KICTLPSPPSPLASLAPVADSSTR 24 1 Q9UER7-3;Q9UER7;Q9UER7-2 Q9UER7-3 DAXX Death domain-associated protein 6 1 0 KICT(0.001)LPSPPS(0.999)PLASLAPVADSSTR;KICT(0.001)LPS(0.001)PPS(0.991)PLAS(0.007)LAPVADSSTR ; 122.11 3.97E-07 114058000 2429.9 2194.63 2248.9 2621.8 2461.3 2951.6 2564.5 1669.81 2674.2 2560.6 TRUE FALSE FALSE 2237.570851 2384.324038 2332.246212 2610.951686 2431.950605 2339.404889 2636.452968 2178.927382 2380.846951 2649.580659 0.844499994 0.89988732 0.8802322 0.985420722 0.917862454 0.882934015 0.99504537 0.822366881 0.898575004 1 11.37154833 -9.566735766 1.360816421 0.999693312 0.899905097 0 0.059811886 0.395150076 1.317978769 0.035748211 0.008507992 2.71E-10 9.566735766 -0.099788215 KIDAGTMAEPS(ph)ASPSK ddPTM_HeLa_Curcumin_4h_R1 3 KIDAGTMAEPSASPSK 16 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 0 KIDAGTMAEPS(0.601)AS(0.368)PS(0.031)K;KIDAGTMAEPS(0.791)AS(0.203)PS(0.006)K;KIDAGTMAEPS(0.852)AS(0.147)PS(0.001)K ;; 147.75 0.00016893 160483000 29880.5 22889.6 25976.9 26450.3 26940.1 32649.5 23915 9947.9 29109.4 23526 TRUE FALSE FALSE 27515.4269 24868.07503 26939.62677 26340.85567 26618.8569 25877.62566 24585.99054 12980.96892 25916.17165 24343.52675 1.130297478 1.021547752 1.106644368 1.08204764 1.093467564 1.063018762 1.009960093 0.533241097 1.06460218 1 14.57125057 -4.254301332 3.458876236 1.06652852 0.46247269 0.951166123 0.036263703 0.063568148 1.277794093 0.006937384 0.101244528 5.57E-05 4.254301332 -0.60405583 KIDAGTMAEPSAS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 KIDAGTMAEPSASPSK 16 1 Q8IXQ3 Q8IXQ3 C9orf40 Uncharacterized protein C9orf40 1 0 KIDAGTMAEPS(0.199)AS(0.602)PS(0.199)K 107.78 0.0011386 18682000 4903.1 4222.4 4625.3 5121.1 5088.3 5752.3 4973.5 1671.4 5363.7 4606.2 TRUE FALSE FALSE 4515.014461 4587.365441 4796.717687 5099.910245 5027.625346 4559.208138 5113.043025 2181.002166 4775.315529 4766.265107 0.947285633 0.96246544 1.006389191 1.070001381 1.054835439 0.956557815 1.072756741 0.457591451 1.00189885 1 12.21864348 -4.256085132 24.99983311 0.99117348 0.457591227 0.926924081 0.046147078 116.9173808 545888.7925 0.006869646 0.078739752 5.55E-05 4.256085132 -0.533582253 KIDK(ac)YTEVLK ddPTM_HeLa_Curcumin_4h_R1 1 KIDKYTEVLK 10 2 Q8J015;M0QYS1;P40429 Q8J015 RPL13a;RPL13A 60S ribosomal protein L13a 0 1 K(0.002)IDK(0.998)YTEVLK 89.266 0.0067002 0 497.64 441.17 384.06 465.53 607.64 766.11 757.49 730.99 1107.6 612.55 FALSE TRUE FALSE 458.2512689 479.302769 398.2936015 463.6037602 600.3942899 607.2101502 778.7431307 953.8654859 986.0990511 633.8360669 0.72298074 0.756193587 0.628385828 0.731425339 0.947239075 0.957992424 1.228619152 1.504908817 1.555763552 1 9.307965945 -4.515182412 1.315599322 0.831151953 1.635217586 0.346749304 0.251324658 0.359865198 0.737275997 0.020851415 0.340107488 3.05E-05 4.515182412 0.804065633 KIEEAMDGSET(ph)PQLFTVLPEK ddPTM_HeLa_Curcumin_4h_R1 2 KIEEAMDGSETPQLFTVLPEK 21 1 E9PPJ0;Q13435 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 0 KIEEAMDGS(0.001)ET(0.999)PQLFTVLPEK;KIEEAMDGS(0.002)ET(0.994)PQLFT(0.005)VLPEK ; 98.188 0.00011747 34626000 4554.2 4339.5 4517.2 4435 4724.2 5974.8 5173 5377.1 4411.4 4261.5 TRUE FALSE FALSE 4193.730264 4714.587044 4684.611406 4416.649145 4667.867 4735.55913 5318.140458 7016.553037 3927.480457 4409.586808 0.951048352 1.069167532 1.062369698 1.001601587 1.058572425 1.073923553 1.206040541 1.591204197 0.890668588 1 12.10642776 -1.000000004 0.74548617 0.990235845 105.1768867 0.930924924 0.04860898 52.04393874 0.214806893 0.006954385 9109.892915 0.099999999 1.000000004 104.1866509 KIEEAMDGSET(ph)PQLFTVLPEKR ddPTM_HeLa_Curcumin_4h_R1 2 KIEEAMDGSETPQLFTVLPEKR 22 2 E9PPJ0;Q13435 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 0 KIEEAMDGS(0.154)ET(0.8)PQLFT(0.047)VLPEKR;KIEEAMDGS(0.151)ET(0.814)PQLFT(0.035)VLPEKR ; 53.342 0.0080138 138527000 3348.45 2666.04 3050.57 3606.52 3159.65 4768.8 3529.5 3424.63 3610.2 3342.9 TRUE FALSE FALSE 3083.416649 2896.480618 3163.626808 3591.597176 3121.973237 3779.697125 3628.528271 4468.783922 3214.170092 3459.065526 0.89140163 0.83735928 0.91459002 1.038314293 0.902548163 1.092693126 1.048990903 1.291904963 0.929201852 1 11.75616663 -2.853014961 0.697840458 0.938681027 3.461579973 0.755113138 0.062092165 6.862955544 0.510011832 0.011342883 21.39120437 0.001402765 2.853014961 2.522898946 KIEFSLPDLEGR ddPTM_HeLa_Curcumin_4h_R1 1 KIEFSLPDLEGR 12 1 P35998;P35998-2 P35998 PSMC2 26S protease regulatory subunit 7 0 0 92.906 0.01944 9895300 2345.3 1630.7 1810.8 1631.7 1864.2 2309.3 1836.2 2107.3 2150.8 2064.6 FALSE FALSE TRUE 2159.66703 1771.650442 1877.909841 1624.948458 1841.970633 1830.325149 1887.71883 2749.806069 1914.862621 2136.344696 1.010916934 0.829290538 0.879029421 0.760620915 0.862206663 0.856755538 0.883620903 1.287154678 0.89632662 1 11.06092873 -7.285466083 23.44499835 1.005155233 0.896856516 0.014997815 0.138080806 540.2104426 527129.8953 0.022058722 0.025234872 5.18E-08 7.285466083 -0.108298718 KILDSVGIEADDDRLNK ddPTM_HeLa_Curcumin_4h_R1 2 KILDSVGIEADDDRLNK 17 2 P05387 P05387 RPLP2 60S acidic ribosomal protein P2 0 0 ; ; 97.223 0.0010427 85177000 7805.8 5868.4 6773 6912.2 6633.9 8465.1 6073.8 6174.8 7739.7 6205.1 FALSE FALSE TRUE 7187.962693 6375.638347 7024.013338 6883.599148 6554.795075 6709.342839 6244.214481 8057.468095 6890.674274 6420.726763 1.119493627 0.992977677 1.093959235 1.072090341 1.020880551 1.044950686 0.972508987 1.254915275 1.073192261 1 12.64852089 -9.630344134 1.452553044 1.000036492 1.071986994 0 0.077818722 0.713575259 2.70701713 0.049379357 0.01127888 2.34E-10 9.630344134 0.071950502 KIMLS(ph)DEMET(ph)EK ddPTM_HeLa_Curcumin_4h_R1 2 KIMLSDEMETEK 12 1 H0YMX9;H0YNN2;H0YLX5;Q96M60-2;Q96M60 H0YMX9 FAM227B Protein FAM227B 2 0 KIMLS(1)DEMET(1)EK;KIMLS(1)DEMET(1)EK ; 78.508 0.018574 43767000 6967.4 4841.93 5417.2 6367.2 4959.18 6689 5415.6 4460.19 6545.6 6822.3 TRUE FALSE FALSE 6415.922938 5260.444854 5617.966197 6340.854213 4900.045017 5301.625999 5567.547161 5820.081399 5827.564056 7059.374417 0.908851487 0.745171533 0.795816437 0.898217581 0.694118873 0.751005073 0.788674298 0.82444719 0.82550715 1 12.78532463 -7.658923185 0.896155507 0.981470134 0.779931203 0.253914279 0.074370556 0.201228896 0.340030903 0.014782826 0.014018393 2.19E-08 7.658923185 -0.201538932 KIMS(ph)SPLSK ddPTM_HeLa_Curcumin_4h_R1 1 KIMSSPLSK 9 1 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;Q9UNX3;P61254;J3QRC4;E5RHH1;J3KSS0 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 1 0 KIMS(0.983)S(0.016)PLS(0.001)K 74.962 0.018289 14664000 3542.8 3240.1 2920.5 2756.5 2788 4707.8 3514.7 2581.2 4012.2 2987.7 TRUE FALSE FALSE 3262.383642 3520.159806 3028.736299 2745.094333 2754.754921 3731.349212 3613.313023 3368.195998 3572.071698 3091.522353 1.055267687 1.138649314 0.979690895 0.88794258 0.891067444 1.206961745 1.168781141 1.089494305 1.155441006 1 11.59410172 -5.242286906 24.99193719 1.01332984 1.156449276 0.347491658 0.087650001 655.1038868 854839.42 0.011468732 0.029189585 5.72E-06 5.242286906 0.143119436 KIPDPDS(ph)DDVSEVDAR ddPTM_HeLa_Curcumin_4h_R1 2 KIPDPDSDDVSEVDAR 16 1 P51532;P51532-4;P51532-3;P51532-2;P51532-5;A0A0A0MT49;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8Y440;A0A2R8Y4C5;A0A2R8Y6N0;A0A2R8YG32;A0A2R8Y7F3;A0A2R8YF80;A0A2R8YF58;A0A2R8Y526;A0A2R8Y7Y7;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8YGP5;A0A2R8Y7R0;A0A2R8Y583 P51532 SMARCA4 Transcription activator BRG1 1 0 KIPDPDS(0.617)DDVS(0.383)EVDAR;KIPDPDS(0.513)DDVS(0.487)EVDAR ; 127.67 0.0002267 50758000 7747.4 6490.8 7387.4 7778 7737.3 8859.9 8216.8 6031.5 8904.6 7892.1 TRUE FALSE FALSE 7134.185115 7051.83583 7661.183543 7745.816697 7645.037751 7022.256868 8447.341294 7870.476584 7927.787658 8166.349888 0.873607574 0.863523597 0.938140497 0.948504142 0.936163385 0.859901543 1.034408446 0.963769211 0.970787165 1 12.99547567 -4.742730527 24.99749202 0.929463696 0.999088816 0.286213176 0.046869582 311.825822 416633.6526 0.007939993 0.029600543 1.81E-05 4.742730527 0.069625119 KIPEFEVENS(ph)PLSDVAK ddPTM_HeLa_Curcumin_4h_R1 1 KIPEFEVENSPLSDVAK 17 1 Q5VY60;Q7Z4H7-3;Q7Z4H7;Q5SYF9;Q7Z4H7-2 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 0 KIPEFEVENS(1)PLSDVAK 118.05 0.00034016 37157000 3618.1 2620.5 3108.5 3024.7 2842.3 4388.6 3153.2 1080.8 3550 2501.3 TRUE FALSE FALSE 3331.723567 2847.004343 3223.703745 3012.184593 2808.407429 3478.35489 3241.670306 1410.330945 3160.573882 2588.219989 1.287264445 1.099985455 1.245529267 1.163805475 1.085072923 1.343917791 1.252470934 0.544903814 1.221138039 1 11.33774453 -4.256247842 24.91113605 1.161356943 0.544903543 0.779275997 0.101867304 234.1457971 1123489.95 0.017446594 0.196376053 5.54E-05 4.256247842 -0.6164534 KIPEPSPVT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 KIPEPSPVTR 10 1 A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YHT2;Q7Z4S6-3;H0YI78 A0A1B0GV47 KIF21A Kinesin-like protein KIF21A 1 0 KIPEPS(0.011)PVT(0.989)R 75.652 0.019459 241330000 3961.8 3463.5 3436.7 4277.3 3972.6 4656.5 3508.5 1983.1 4208 4039.6 TRUE FALSE FALSE 3648.21935 3762.869507 3564.067125 4259.601666 3925.22934 3690.68941 3606.939067 2587.738061 3746.392928 4179.975799 0.872784802 0.900213228 0.852652574 1.019049361 0.939055518 0.882945162 0.862909079 0.619079675 0.89627144 1 12.02927887 -3.846920287 1.294363023 0.934109713 0.118465548 0.755822149 0.051084405 1.455537649 1.009970786 0.008937546 2.037782372 0.000142259 3.846920287 -0.815644166 KIQALQQQADEAEDR ddPTM_HeLa_Curcumin_4h_R1 2 KIQALQQQADEAEDR 15 1 P67936;A0A2R8Y5V9;A0A2R8YGX3;A0A590UK79;A0A590UJB9 P67936 TPM4 Tropomyosin alpha-4 chain 0 0 ; ; 161.49 9.11E-09 33946000 3902.3 3587.2 3430 3789.6 3109.7 4075.6 3562.6 3391.3 4184.9 3387.9 FALSE FALSE TRUE 3593.428837 3897.261584 3557.118817 3773.919639 3072.618859 3230.274619 3662.556968 4425.291758 3725.82694 3505.629273 1.025045308 1.111715267 1.014687675 1.0765313 0.876481402 0.921453573 1.044764487 1.262338774 1.062812594 1 11.77545772 -4.279533624 4.098725568 1.008825064 1.279750654 0.560845617 0.066172388 0.113231453 4.053380135 0.008932555 0.087305698 5.25E-05 4.279533624 0.27092559 KIQSSLSSAS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 KIQSSLSSASPSK 13 1 Q5W0B1 Q5W0B1 RNF219 RING finger protein 219 1 0 KIQSSLS(0.001)S(0.122)AS(0.867)PS(0.009)K 92.264 0.0051601 31653000 4302.5 3409.6 3307.3 3633.1 3721 4838.8 3297.3 1792.1 4588.3 4022.3 TRUE FALSE FALSE 3961.952585 3704.310631 3429.871447 3618.067195 3676.629505 3835.178335 3389.813364 2338.50304 4084.974969 4162.074626 0.951917719 0.890015428 0.824077355 0.869294167 0.883364628 0.92145833 0.814452807 0.56185995 0.981475667 1 12.02308712 -2.93951492 0.333545315 0.980089867 9.54E-41 0.695650978 0.065137602 6.629252355 0.264308818 0.022912872 3.155151659 0.001149437 2.93951492 -0.980089867 KIQVLQQQADDAEER ddPTM_HeLa_Curcumin_4h_R1 2 KIQVLQQQADDAEER 15 1 A0A087WWU8;P06753-2;P06753-5;P06753-3;P06753-6;P06753-4;D6R904;Q5VU61 A0A087WWU8 TPM3 Tropomyosin alpha-3 chain 0 0 ; ; 151.56 6.54E-17 2390700 2714.72 1964.44 2356.79 2367.83 2450.22 2829.9 2372.19 2461.62 2176.99 2259.52 FALSE FALSE TRUE 2499.847047 2134.23744 2444.134711 2358.032547 2421.002727 2242.94684 2438.747267 3212.156606 1938.179644 2338.038152 1.069207124 0.912832598 1.045378455 1.008551783 1.035484697 0.959328589 1.043074197 1.373868345 0.82897691 1 11.19108276 -4.264363582 4.865493064 1.019643042 1.392073318 0.693865157 0.074367979 0.047116655 3.269674087 0.006246378 0.058924848 5.44E-05 4.264363582 0.372430276 S(ph)WVIGSPEILR ddPTM_HeLa_Curcumin_4h_R1 1 SWVIGSPEILR 11 0 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 0 S(0.993)WVIGS(0.007)PEILR 138.22 0.0016145 62257000 3572.1 2967.3 3140 3285 2949 3262 2174.4 1102.7 3139.5 2788.2 TRUE FALSE FALSE 3289.364516 3223.78019 3256.371162 3271.40754 2913.835101 2585.42443 2235.407812 1438.908154 2795.104705 2885.089742 1.140125545 1.117393384 1.12868973 1.133901484 1.009963419 0.896133105 0.774813961 0.498739479 0.968810316 1 11.49440048 -4.412197985 1.033959677 1.081139171 0.302272451 0.907007806 0.058717291 0.329955336 0.324394186 0.010035845 0.265537619 3.87E-05 4.412197985 -0.77886672 down KISENS(ph)YSLDDLEIGPGQLSSSTFDSEK ddPTM_HeLa_Curcumin_4h_R1 2 KISENSYSLDDLEIGPGQLSSSTFDSEK 28 1 Q9UHB6;F8VQE1;Q9UHB6-2;F8VRN8;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 KIS(0.313)ENS(0.451)Y(0.023)S(0.213)LDDLEIGPGQLSSSTFDSEK;KIS(0.336)ENS(0.466)Y(0.004)S(0.194)LDDLEIGPGQLSSSTFDSEK ; 113.7 2.11E-10 116152000 8074.3 6972.4 7826 7170 8630.3 7641.7 3137.96 2331.12 7461.4 5273.5 TRUE FALSE FALSE 7435.210635 7575.063188 8116.038444 7140.33244 8527.389309 6056.72528 3226.002712 3041.867757 6642.903088 5456.753732 1.362570312 1.38819957 1.487338231 1.308531187 1.562722037 1.10995027 0.591194485 0.557450071 1.217372712 1 12.41382722 -4.807517581 4.015681684 1.25153373 0.559705785 0.769898576 0.159274613 0.098273936 3.266682771 0.029497274 0.104400524 1.56E-05 4.807517581 -0.691827945 KISSDLDGHPVPK ddPTM_HeLa_Curcumin_4h_R1 1 KISSDLDGHPVPK 13 1 P29401;P29401-2;E9PFF2;F8W888 P29401 TKT Transketolase 0 0 57.802 0.010021 4323100 7562.1 5984.1 5448 5525.8 8466.7 10624 6743.3 5869.7 8022 6605.4 FALSE FALSE TRUE 6963.551806 6501.338939 5649.907673 5502.935704 8365.740132 8420.462643 6932.498849 7659.344509 7142.00667 6834.937158 1.018817239 0.951192204 0.826621744 0.805118698 1.223967381 1.231973674 1.01427397 1.120616669 1.044926457 1 12.73871236 -5.740203316 24.99998819 0.976360847 1.144195903 0.510721525 0.095365593 196.8252807 231709.7363 0.014963294 0.029903248 1.82E-06 5.740203316 0.167835056 KITSLSS(ph)SLDTSLDFSK ddPTM_HeLa_Curcumin_4h_R1 1 KITSLSSSLDTSLDFSK 17 1 E9PR71;Q9P2Y5-2;Q9P2Y5 E9PR71 UVRAG UV radiation resistance-associated gene protein 1 0 KIT(0.001)S(0.006)LS(0.026)S(0.842)S(0.125)LDTSLDFSK 86.625 0.002817 21921000 2269.3 2008.5 2107.4 2238.1 2118.8 2136.8 1294.3 849.22 1949.3 1954.5 TRUE FALSE FALSE 2089.68251 2182.10579 2185.502098 2228.839335 2093.534694 1693.603593 1330.614575 1108.143269 1735.466667 2022.41873 1.033259077 1.078958456 1.080637786 1.102066206 1.035163818 0.837414907 0.657932284 0.547929691 0.858114416 1 10.98186601 -4.877301082 1.873750104 1.034241816 0.559166964 0.870135195 0.065896796 0.060206034 0.393378372 0.006418963 0.032703136 1.33E-05 4.877301082 -0.475074851 KITSLSSS(ph)LDTSLDFSK ddPTM_HeLa_Curcumin_4h_R1 1 KITSLSSSLDTSLDFSK 17 1 E9PR71;Q9P2Y5-2;Q9P2Y5 E9PR71 UVRAG UV radiation resistance-associated gene protein 1 0 KIT(0.001)S(0.001)LS(0.001)S(0.097)S(0.886)LDT(0.008)S(0.007)LDFSK 63.674 0.013274 15482000 1899.3 1522.8 1692.2 1658 1561.1 1784.6 1186.7 675.18 1887.2 1456.1 TRUE FALSE FALSE 1748.968401 1654.424047 1754.914421 1651.139635 1542.484902 1414.453843 1219.995608 881.0392739 1680.178882 1506.699367 1.160794542 1.098045226 1.164740929 1.095865354 1.023750946 0.938776424 0.809714025 0.584747889 1.115138772 1 10.55717587 -4.423182521 1.029723592 1.087813626 0.414749506 0.925731519 0.047044891 0.386119994 0.380313908 0.010349912 0.266496571 3.77E-05 4.423182521 -0.673064119 KIVEPEVVGES(ph)DS(ph)EVEGDAWR ddPTM_HeLa_Curcumin_4h_R1 2 KIVEPEVVGESDSEVEGDAWR 21 1 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 2 0 KIVEPEVVGES(1)DS(1)EVEGDAWR;KIVEPEVVGES(1)DS(1)EVEGDAWR ; 118.63 5.43E-06 54883000 6121.84 5429.84 4818.05 6411.1 5721.63 6498.16 4757.04 5346.98 7077.76 6163 TRUE FALSE FALSE 5637.289904 5899.171175 4996.611171 6384.572567 5653.403299 5150.368367 4890.509739 6977.249588 6301.347436 6377.163791 0.88398073 0.925046207 0.783516205 1.001161767 0.886507464 0.807626797 0.76687849 1.094099166 0.988111274 1 12.63869922 -9.193876654 0.662390047 1.011346109 0.885396562 0.148592228 0.09440869 1.305790364 0.895779669 0.094668962 0.019329533 6.40E-10 9.193876654 -0.125949546 KIVEPEVVGES(ph)DSEVEGDAWR ddPTM_HeLa_Curcumin_4h_R1 3 KIVEPEVVGESDSEVEGDAWR 21 1 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 1 0 KIVEPEVVGES(0.958)DS(0.042)EVEGDAWR;KIVEPEVVGES(0.982)DS(0.018)EVEGDAWR;KIVEPEVVGES(0.933)DS(0.067)EVEGDAWR ;; 157.61 7.45E-07 89846600 13131.2 9438.6 9630.7 10724.1 8913.2 11865.9 7903 6233.4 12849.7 9564.4 TRUE FALSE FALSE 12091.85166 10254.43053 9987.622214 10679.72652 8806.915911 9404.778584 8124.73691 8133.934965 11440.12006 9896.762188 1.221798749 1.036139935 1.009180783 1.07911318 0.889878502 0.950288428 0.820948989 0.821878389 1.155945737 1 13.2727409 -5.536921005 0.874250829 1.100346402 0.814396023 0.702489608 0.0688916 0.384458217 0.513434516 0.015748652 0.069071558 2.90E-06 5.536921005 -0.285950378 KK(ac)LEMDLK ddPTM_HeLa_Curcumin_4h_R1 1 KKLEMDLK 8 2 P35579;P35579-2 P35579 MYH9 Myosin-9 0 1 K(0.228)K(0.772)LEMDLK 77.533 0.011693 3702900 3526 3844.7 3438 3250.9 6854.8 8739.8 7282.3 5985.2 7753.7 4308.3 FALSE TRUE FALSE 3246.913379 4177.018736 3565.415304 3237.448637 6773.060987 6927.066962 7486.621739 7810.059928 6903.138509 4458.013104 0.72833195 0.936968699 0.799776766 0.726208865 1.519300376 1.553846254 1.679362883 1.751914978 1.548478739 1 12.12218514 -5.686768833 5.089437201 0.859226143 1.641172047 0.644380973 0.238038706 0.044721155 2.098846962 0.01823998 0.036809863 2.06E-06 5.686768833 0.781945904 KK(ac)PSKNQAEK ddPTM_HeLa_Curcumin_4h_R1 1 KKPSKNQAEK 10 3 Q5FYB0 Q5FYB0 ARSJ Arylsulfatase J 0 1 K(0.011)K(0.987)PSK(0.001)NQAEK 79.974 0.0071188 0 3121.4 2713.2 2776.7 3172.7 3406.4 3845.9 3131.4 1708.2 3015.2 2744.1 FALSE TRUE FALSE 2874.337896 2947.716918 2879.606945 3159.572208 3365.780905 3048.216988 3219.258656 2229.022316 2684.440104 2839.457271 1.012284258 1.03812688 1.014139911 1.112738072 1.185360646 1.073520993 1.133758444 0.785017031 0.945406057 1 11.47139949 -6.386104082 7.769992199 1.00922896 1.070138338 0.061368033 0.102689889 0.563002059 33.31552306 0.014626824 0.022363412 4.11E-07 6.386104082 0.060909378 KK(ac)VEAQLQELQVK ddPTM_HeLa_Curcumin_4h_R1 1 KKVEAQLQELQVK 13 2 P35579 P35579 MYH9 Myosin-9 0 1 K(0.01)K(0.99)VEAQLQELQVK 151.54 4.31E-05 1595600 906.36 686.13 701.23 657.79 693.45 933.51 775.15 502.94 944.26 662.05 FALSE TRUE FALSE 834.6206496 745.4360199 727.2182007 655.0682393 685.1810617 739.8895032 796.8986228 656.2840907 840.6770404 685.0561882 1.218324371 1.08813851 1.061545335 0.956225563 1.000182282 1.080042069 1.163260235 0.958000383 1.227165092 1 9.420078512 -6.716937005 3.896630488 1.105127695 1.037664566 0.217926912 0.084307342 0.429464752 13.64611961 0.015849683 0.022304258 1.92E-07 6.716937005 -0.067463129 KK(ac)YVIYIER ddPTM_HeLa_Curcumin_4h_R1 1 KKYVIYIER 9 2 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;Q9UNX3;P61254;J3QRC4;J3KS10 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 0 1 K(0.153)K(0.847)YVIYIER 73.499 0.015245 9716100 8965 6079.1 6897.2 5951.4 7039.3 9612.3 8841.8 8055 7573.7 7514.4 FALSE TRUE FALSE 8255.41079 6604.550316 7152.816299 5926.774684 6955.360945 7618.600627 9089.877112 10510.93242 6742.884058 7775.524841 1.061717499 0.84940251 0.919914275 0.762234679 0.894519803 0.979818184 1.169037113 1.351797163 0.86719343 1 12.92472434 -4.516980572 2.498121105 0.97743624 1.355074937 0.65211286 0.09671177 0.197597918 2.109722918 0.015616114 0.123754311 3.04E-05 4.516980572 0.377638696 KKAEPSEVDMNS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 KKAEPSEVDMNSPK 14 2 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 0 KKAEPSEVDMNS(1)PK;KKAEPSEVDMNS(1)PK ; 88.319 0.0033444 957270000 24532 19088.3 22312 25068 21174 27930 24418 8420.9 25725 20626 TRUE FALSE FALSE 22590.26631 20738.2076 23138.90235 24964.27526 20921.51388 22137.00316 25103.10336 10988.39364 22903.03186 21342.75196 1.058451429 0.971674488 1.084157394 1.169683989 0.980263179 1.037214095 1.176188685 0.514853645 1.073105844 1 14.38145859 -4.252407056 24.89667192 1.042544406 0.514853355 0.847748712 0.069053533 314.3424821 866433.2938 0.009242011 0.151550076 5.59E-05 4.252407056 -0.527691051 KKDAS(ph)DDLDDLNFFNQK ddPTM_HeLa_Curcumin_4h_R1 1 KKDASDDLDDLNFFNQK 17 2 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 1 0 KKDAS(1)DDLDDLNFFNQK 45.722 0.018758 22869000 2997.5 2610.9 2117.2 2912.3 2586.5 3243.9 2857.3 1494.1 2481.2 2413.9 TRUE FALSE FALSE 2760.244712 2836.574562 2195.665294 2900.249674 2555.657677 2571.078574 2937.468148 1949.644212 2209.018568 2497.782845 1.105077936 1.135636978 0.87904571 1.161129631 1.023170482 1.029344316 1.176030236 0.780549925 0.88439176 1 11.28643234 -4.244717907 24.40930682 1.055546699 0.780549626 0.379743073 0.099899288 1563.693032 2282564.351 0.010986094 0.4062554 5.69E-05 4.244717907 -0.274997073 KKDASDDLDDLNFFNQK ddPTM_HeLa_Curcumin_4h_R1 1 KKDASDDLDDLNFFNQK 17 2 P20042 P20042 EIF2S2 Eukaryotic translation initiation factor 2 subunit 2 0 0 70.197 0.0074605 14570000 3615.3 2515.2 2637.2 2985 2390.3 3401.2 2449.1 2503.5 3451.1 3096.5 FALSE FALSE TRUE 3329.14519 2732.60268 2734.936952 2972.648861 2361.797234 2695.752781 2517.815155 3266.805625 3072.522964 3204.103145 1.039025599 0.852844792 0.853573318 0.927763161 0.737116481 0.841343945 0.785809645 1.019569433 0.95893385 1 11.64570488 -7.257155268 24.26502118 1.018428757 0.853833411 0.415702995 0.074595334 130.1754876 737308.0919 0.011373782 0.013662419 5.53E-08 7.257155268 -0.164595346 KKDDS(ph)FLGK ddPTM_HeLa_Curcumin_4h_R1 1 KKDDSFLGK 9 2 Q9NVD7-2;Q9NVD7 Q9NVD7-2 PARVA Alpha-parvin 1 0 KKDDS(1)FLGK 53.013 0.019722 28757000 8439.6 6152.2 6919 6849.5 7127.1 10598 9131.4 3784.1 7332.2 5883 TRUE FALSE FALSE 7771.596755 6683.968754 7175.424227 6821.158584 7042.113987 8399.855336 9387.602508 4937.85467 6527.876004 6087.433812 1.276662218 1.097994485 1.178727268 1.120531047 1.156828017 1.379868036 1.542128062 0.811155377 1.072352687 1 12.57161847 -9.435890602 0.991572973 0.990931518 1.21211263 0.099487487 0.182184313 0.877841328 1.437868796 0.146512574 0.031091124 3.67E-10 9.435890602 0.221181111 EK(ac)TPSPKEEDEEPESPPEKK ddPTM_HeLa_Curcumin_4h_R1 1 EKTPSPKEEDEEPESPPEKK 20 3 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 0 1 EK(1)TPSPKEEDEEPESPPEKK 102.84 0.00028317 9135000 1179.5 621.07 880.27 969.38 838.85 1461.3 1400.3 1770.3 1379.7 786.94 FALSE TRUE FALSE 1086.14133 674.7525234 912.8935806 965.3689624 828.8472616 1158.209908 1439.588649 2310.056321 1228.350362 814.2861064 1.333857132 0.828643051 1.12109684 1.18554026 1.017882112 1.42236236 1.767915034 2.836909905 1.508499718 1 9.669391977 -4.129377398 1.246247601 1.125851684 4.010597028 0.88834239 0.182194406 0.373409968 0.393667304 0.023818347 1.486913364 7.42E-05 4.129377398 2.884745344 up KKEEPSQNDIS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 KKEEPSQNDISPK 13 2 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 0 KKEEPS(0.001)QNDIS(0.999)PK;KKEEPSQNDIS(1)PK ; 58.164 0.016026 3555000000 15648.2 13040.7 15388.2 17774.5 15391 16659.5 13886.7 10130.5 18318 15469.4 TRUE FALSE FALSE 14409.62846 14167.88 15958.50023 17700.95383 15207.47238 13204.13191 14276.32343 13219.24281 16308.56123 16006.9605 0.900210159 0.885107451 0.99697255 1.105828544 0.950053721 0.824899387 0.891882218 0.825843408 1.018841849 1 13.96641177 -5.310918599 7.149806813 0.961795427 0.852073025 0.465291669 0.06284122 0.210956115 26.33152404 0.009891258 0.02237053 4.89E-06 5.310918599 -0.109722401 KKEESTAASETTEGSQGDSK(ac)NAK ddPTM_HeLa_Curcumin_4h_R1 1 KKEESTAASETTEGSQGDSKNAK 23 3 Q92793;Q92793-2 Q92793 CREBBP CREB-binding protein 0 1 KKEESTAASETTEGSQGDSK(1)NAK 96.467 4.71E-05 91612000 10565 8547.8 10326 10532 11150 8414.8 8448.3 5145.6 9064.9 8391.6 FALSE TRUE FALSE 9728.769102 9286.633744 10708.69064 10488.42137 11017.04353 6669.475626 8685.336561 6714.469753 8070.503149 8683.207475 1.120411913 1.069493476 1.233264398 1.207897128 1.268775802 0.76808894 1.000245196 0.77327068 0.929438018 1 13.08401234 -5.249386357 24.94150378 1.096468499 0.862505963 0.526721782 0.11626487 508.9421433 1053159.52 0.016254076 0.041073964 5.63E-06 5.249386357 -0.233962536 KKEPAITSQNS(ph)PEAR ddPTM_HeLa_Curcumin_4h_R1 2 KKEPAITSQNSPEAR 15 2 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193;E5RIS7 A0A1W2PRL9 TCEA1 Transcription elongation factor A protein 1 1 0 KKEPAITS(0.001)QNS(0.999)PEAR;KKEPAITSQNS(1)PEAR ; 123.54 0.00076301 1526400000 16836.5 14490.6 15069.6 14986.2 16668.1 18716.6 15703.3 15076.4 16080.6 14180 TRUE FALSE FALSE 15503.87326 15743.1029 15628.09263 14924.19108 16469.34379 14834.56618 16143.89233 19673.12496 14316.59841 14672.75394 1.056643716 1.072948061 1.065109705 1.017136328 1.122443943 1.011028075 1.100263277 1.340792944 0.975726743 1 13.84085206 -4.270694354 2.775003056 1.038623047 1.394039814 0.833991337 0.040103556 0.114887855 1.211809132 0.005337403 0.091651866 5.36E-05 4.270694354 0.355416767 KKETVSEAPPLLFS(ph)DEEEKEAQLGVK ddPTM_HeLa_Curcumin_4h_R1 1 KKETVSEAPPLLFSDEEEKEAQLGVK 26 3 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q641Q2;F8W7U3;E7ESD2;Q641Q2-2 A0A0A0MR88;Q641Q2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 0 KKETVSEAPPLLFS(1)DEEEKEAQLGVK 66.732 0.00037306 30795000 1971.3 1536.3 1807.8 1798.6 1587.7 2287.6 1573.5 887.75 2302.5 1976 TRUE FALSE FALSE 1815.269525 1669.090926 1874.798658 1791.15787 1568.767714 1813.125973 1617.648175 1158.420888 2049.921511 2044.665853 0.887807425 0.816314766 0.916921782 0.876014957 0.767248943 0.886759062 0.791155275 0.566557556 1.002570424 1 10.99764938 -2.116535528 0.191086555 0.996100367 1.11E-23 0.696874051 0.066408163 16.09897009 0.26276089 0.077097142 4.370494043 0.007646531 2.116535528 -0.996100367 KKEVDATS(ph)PAPSTSSTVK ddPTM_HeLa_Curcumin_4h_R1 1 KKEVDATSPAPSTSSTVK 18 2 X6RHM1;Q16666-3;Q16666-2;Q16666;H3BM18;Q16666-6 X6RHM1 IFI16 Gamma-interferon-inducible protein 16 1 0 KKEVDAT(0.02)S(0.918)PAPS(0.052)T(0.005)S(0.002)S(0.002)T(0.001)VK 90.06 0.0020494 17325000 3588.3 2840.4 3653.8 3728.8 3699.7 4968.5 4635.7 2013.6 4927 3511.2 TRUE FALSE FALSE 3304.282269 3085.911519 3789.213042 3713.371214 3655.583494 3937.977093 4765.765266 2627.537371 4386.520427 3633.213939 0.909465373 0.849361357 1.042936944 1.02206236 1.006156961 1.083882524 1.311721618 0.723199188 1.207338874 1 11.8270306 -6.586451431 24.96930738 0.947875026 1.045391725 0 0.161097348 104.3258174 40974.93766 0.020460476 0.028935485 2.59E-07 6.586451431 0.097516699 KKGDDS(ph)DEEDLCISNK ddPTM_HeLa_Curcumin_4h_R1 1 KKGDDSDEEDLCISNK 16 2 H3BRG5;Q9Y3M8-5;Q9Y3M8-3;Q9Y3M8-4;Q9Y3M8-2;Q9Y3M8 H3BRG5 STARD13 StAR-related lipid transfer protein 13 1 0 KKGDDS(1)DEEDLCISNK 98.443 0.0023921 36956000 2637.4 1958.2 2085.2 2460.4 2300.4 2298.9 1569.1 1299.6 2581.5 2269.4 TRUE FALSE FALSE 2428.647007 2127.458082 2162.479346 2450.219517 2272.969232 1822.082226 1613.124723 1695.842057 2298.315909 2348.261481 1.034231931 0.905971545 0.920885244 1.043418519 0.967937025 0.775928167 0.68694425 0.722169175 0.97873083 1 11.19737735 -5.20645644 2.787691997 1.001592921 0.706866397 0.86870891 0.044694763 0.067227001 1.023708925 0.007032955 0.020196051 6.22E-06 5.20645644 -0.294726523 KKIPDPDS(ph)DDVSEVDAR ddPTM_HeLa_Curcumin_4h_R1 1 KKIPDPDSDDVSEVDAR 17 2 P51532;P51532-4;P51532-3;P51532-2;P51532-5;A0A0A0MT49;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8Y440;A0A2R8Y4C5;A0A2R8Y6N0;A0A2R8YG32;A0A2R8Y7F3;A0A2R8YF80;A0A2R8YF58;A0A2R8Y526;A0A2R8Y7Y7;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8YGP5;A0A2R8Y7R0;A0A2R8Y583 P51532 SMARCA4 Transcription activator BRG1 1 0 KKIPDPDS(0.982)DDVS(0.018)EVDAR 89.816 0.0031523 15031000 3155 2189.5 2856.4 3105.9 2423.1 3069.7 2531.5 2405.9 3677.7 3075.8 TRUE FALSE FALSE 2905.278421 2378.750624 2962.260697 3093.048609 2394.206115 2433.009617 2602.527077 3139.447835 3274.265511 3182.683821 0.912839158 0.747404002 0.930743003 0.971836595 0.752260121 0.76445219 0.817714615 0.986415243 1.028774988 1 11.63602813 -8.170391478 0.654997041 0.995311024 0.847663216 0.334658584 0.085476235 0.599990517 0.570189756 0.03844532 0.022615256 6.75E-09 8.170391478 -0.147647808 KKLDDQS(ph)EDEALELEGPLITPGSGSIYSSPGLYSK ddPTM_HeLa_Curcumin_4h_R1 2 KKLDDQSEDEALELEGPLITPGSGSIYSSPGLYSK 35 2 Q96AC1;Q96AC1-3;G3V3J0;Q96AC1-2 Q96AC1 FERMT2 Fermitin family homolog 2 1 0 KKLDDQS(0.993)EDEALELEGPLIT(0.006)PGSGS(0.001)IYSSPGLYSK;KKLDDQS(0.967)EDEALELEGPLIT(0.026)PGS(0.001)GS(0.002)IY(0.002)S(0.002)S(0.001)PGLYSK ; 60.843 0.00013088 195827000 4091.1 3137.9 3166.9 3858.2 3192.8 4389.6 3084.6 2233.8 4200.6 3753 TRUE FALSE FALSE 3767.285118 3409.126094 3284.2681 3842.235791 3154.727945 3479.147479 3171.145574 2914.875337 3739.804689 3883.416471 0.970095571 0.877867754 0.845716169 0.98939576 0.812358903 0.895898626 0.816586528 0.750595605 0.963019217 1 11.92311072 -1.000000555 0.162313541 1.031119993 2.07E-10 0.609435047 0.051030134 24.88951039 0.254111133 0.082047131 6.188084129 0.099999872 1.000000555 -1.031119993 KKLGAGEGGEASVS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 1 KKLGAGEGGEASVSPEK 17 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 KKLGAGEGGEAS(0.029)VS(0.971)PEK 60.918 0.0096729 61846000 4570 3985.9 3923.5 4045.4 4003.1 4496.3 3916.6 2542.6 4619.1 3981.2 TRUE FALSE FALSE 4208.279678 4330.423435 4068.908361 4028.661207 3955.365647 3563.716696 4026.489255 3317.827035 4112.396286 4119.546404 1.021539574 1.051189381 0.98770786 0.977938057 0.960145914 0.865075022 0.977410826 0.805386494 0.998264344 1 12.00826978 -4.291874267 0.521790327 1.014264262 0.731234404 0.671214817 0.040250778 1.662351389 0.308719414 0.007703411 0.28443079 5.11E-05 4.291874267 -0.283029858 KKPAPGPHS(ph)SPPEEK ddPTM_HeLa_Curcumin_4h_R1 1 KKPAPGPHSSPPEEK 15 2 M0QYC5;O75182-2;O75182 M0QYC5 SIN3B Paired amphipathic helix protein Sin3b 1 0 KKPAPGPHS(0.5)S(0.5)PPEEK 53.188 0.01705 14834000 8199.9 6097.4 6863.1 7205.6 6509.3 7954.8 5972.3 4670.6 7952.5 7414.6 TRUE FALSE FALSE 7550.869263 6624.432087 7117.452523 7175.785136 6431.680849 6304.884811 6139.866664 6094.644439 7080.130646 7672.256798 0.984178379 0.863426794 0.927686952 0.93529001 0.838303646 0.821777083 0.80026866 0.794374406 0.922822428 1 12.90543529 -5.800428488 0.393908932 1.005447813 0.743079831 0.690702487 0.039612714 0.515291016 0.122440035 0.011412881 0.054966935 1.58E-06 5.800428488 -0.262367983 KKPAPGPHSS(ph)PPEEK ddPTM_HeLa_Curcumin_4h_R1 1 KKPAPGPHSSPPEEK 15 2 M0QYC5;O75182-2;O75182 M0QYC5 SIN3B Paired amphipathic helix protein Sin3b 1 0 KKPAPGPHS(0.22)S(0.78)PPEEK 59.502 0.013752 15261000 7686 5906.2 6570.4 7918.2 6634.8 8310.2 6542.1 5060.6 8127.1 7296.4 TRUE FALSE FALSE 7077.64499 6416.70561 6813.904804 7885.436586 6555.684343 6586.570845 6725.653719 6603.553644 7235.577463 7549.949357 0.937442711 0.849900484 0.902510001 1.044435693 0.868308386 0.872399341 0.890821037 0.874648734 0.958361059 1 12.88225125 -13.52287874 0.086079355 1.342297284 0.812002804 0.243983161 0.052692782 125.8093599 0.824640755 7.946868919 0.751744907 3.00E-14 13.52287874 -0.53029448 SSGTPGCSSGTERPQS(ph)PGSSK ddPTM_HeLa_Curcumin_4h_R1 1 SSGTPGCSSGTERPQSPGSSK 21 1 Q8IYD8-2;Q8IYD8-3;Q8IYD8 Q8IYD8-2 FANCM Fanconi anemia group M protein 1 0 SSGTPGCSSGT(0.001)ERPQS(0.923)PGS(0.015)S(0.061)K 92.499 0.000175 11031000 1568 1049.7 1672.9 1433.5 1069.1 1345 899.22 301.2 1439.7 1435.8 TRUE FALSE FALSE 1443.891145 1140.431391 1734.899146 1427.568557 1056.351681 1066.031839 924.4496931 393.0344934 1281.768512 1485.693943 0.971863116 0.767608562 1.167736568 0.960876608 0.711015674 0.717531254 0.622234275 0.26454607 0.862740619 1 10.53692123 -4.410881891 0.69266541 0.984512533 6.07E-19 0.763565467 0.115931724 0.76188297 0.286228586 0.01810565 0.562350376 3.88E-05 4.410881891 -0.984512533 down KKPEDS(ph)PSDDDVLIVYELTPTAEQK ddPTM_HeLa_Curcumin_4h_R1 1 KKPEDSPSDDDVLIVYELTPTAEQK 25 2 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 KKPEDS(0.5)PS(0.5)DDDVLIVYELTPTAEQK 82.56 3.62E-05 20982000 2469.3 1881.9 1965.6 2491.4 2023.3 2307 1615.4 1668.9 2555.3 1936.2 TRUE FALSE FALSE 2273.852299 2044.56305 2038.446865 2481.091247 1999.173469 1828.502195 1660.723776 2177.739927 2274.989983 2003.482806 1.134949745 1.020504416 1.017451639 1.238389089 0.997849077 0.912661785 0.828918407 1.086977099 1.135517598 1 10.96829441 -5.525549344 24.99834732 1.070646501 0.935425075 0.345097469 0.09035787 73.09792802 684238.5224 0.013118541 0.026360046 2.98E-06 5.525549344 -0.135221426 GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPSPVAPAPVPS(ph)RR ddPTM_HeLa_Curcumin_4h_R1 1 GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPSPVAPAPVPSRR 43 2 Q9UK76;Q9UK76-3 Q9UK76;Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 1 0 GEGDIHENVDTDLPGS(0.001)LGQS(0.001)EEKPVPAAPVPS(0.454)PVAPAPVPS(0.544)RR 63.727 6.13E-06 11235000 2656.2 2336.3 2251.2 2785.4 2681.2 3386.7 2482.4 3851.6 2862.3 2231.9 TRUE FALSE FALSE 2445.958967 2538.239362 2334.631452 2773.874753 2649.228441 2684.260244 2552.049463 5025.935109 2548.312851 2309.458359 1.059105031 1.099062623 1.010899999 1.20109321 1.147121112 1.162289952 1.105042424 2.176239762 1.103424464 1 11.17333882 -4.259140282 5.014819299 1.062476123 2.232371262 0.957447427 0.067822577 0.026490286 2.067829472 0.010930384 0.107037568 5.51E-05 4.259140282 1.169895139 up KKS(ph)GHPAPS(ph)S(ph)MR ddPTM_HeLa_Curcumin_4h_R1 1 KKSGHPAPSSMR 12 2 Q8N137;Q8N137-3;Q8N137-2 Q8N137 CNTROB Centrobin 3 0 KKS(1)GHPAPS(1)S(1)MR 90.861 0.010636 1729100000 3553.1 2592.7 2669.4 2755.9 2901.8 3227.1 2522.6 2288.5 3183.3 2894.4 TRUE FALSE FALSE 3271.868386 2816.801435 2768.330312 2744.496816 2867.19793 2557.763083 2593.377367 2986.253115 2834.099954 2994.980185 1.092450762 0.940507536 0.924323415 0.916365601 0.957334524 0.854016696 0.865908022 0.997086101 0.946283374 1 11.54833074 -7.127007862 5.204155868 1.043448076 0.916695009 0.340433501 0.053402917 0.118841999 4.586046769 0.008348086 0.010280837 7.46E-08 7.127007862 -0.126753067 KKS(ph)PNELVDDLFK ddPTM_HeLa_Curcumin_4h_R1 1 KKSPNELVDDLFK 13 2 F2Z2K0;Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5 F2Z2K0 NSFL1C NSFL1 cofactor p47 1 0 KKS(1)PNELVDDLFK 85.554 0.0048649 137970000 9050.1 7065 7513.2 8140.6 7237.4 8748.1 7773.8 8455.6 8782.6 7585.4 TRUE FALSE FALSE 8333.775035 7675.667119 7791.645801 8106.916354 7151.098732 6933.645449 7991.911906 11033.67352 7819.170753 7848.992085 1.06176372 0.977917551 0.992693803 1.032860814 0.911084972 0.883380359 1.018208684 1.405743998 0.996200616 1 12.93829169 -4.26292466 6.369479 1.005661047 1.414163764 0.843224899 0.0537213 0.039831122 9.203527394 0.008550573 0.070308642 5.46E-05 4.26292466 0.408502717 KKT(ph)DY(ph)EK ddPTM_HeLa_Curcumin_4h_R1 1 KKTDYEK 7 2 Q7Z2Y8 Q7Z2Y8 GVINP1 Interferon-induced very large GTPase 1 2 0 KKT(1)DY(1)EK 55.441 0.008962 0 1694.1 1121.4 1262.1 1502 1500.2 318.37 754.31 840.75 1033 1235.9 TRUE FALSE FALSE 1560.010197 1218.328819 1308.874536 1495.785122 1482.311095 252.3364732 775.4739085 1097.090805 919.6824844 1278.847433 1.219856378 0.952677221 1.023479817 1.169635316 1.159099246 0.197315541 0.606385006 0.857874658 0.719149494 1 10.32062845 -5.283296658 24.96092486 1.096497746 0.55911104 0.519541062 0.206057152 321.3268912 366953.5581 0.02444047 0.054692786 5.21E-06 5.283296658 -0.537386706 KKTEFLDLDNSPLSPPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 KKTEFLDLDNSPLSPPSPR 19 2 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 0 KKTEFLDLDNSPLS(0.001)PPS(0.999)PR 67.979 0.0033715 138740000 4508.6 3394.8 4225.8 3897.7 4105.4 4910.6 4081.3 4328 4700.8 4460.2 TRUE FALSE FALSE 4151.739553 3688.231385 4382.411865 3881.57235 4056.445786 3892.086206 4195.810294 5647.587276 4185.134001 4615.191618 0.899581187 0.799150217 0.949562278 0.841042512 0.878933341 0.843320609 0.909130247 1.22369508 0.906816953 1 12.17217483 -4.260245611 24.72152815 0.919464796 1.223695193 0.718593239 0.060100164 45.41700005 940397.1995 0.010147514 0.083555357 5.49E-05 4.260245611 0.304230397 KKVEEEDEEEEEEEEEEEEEEDE ddPTM_HeLa_Curcumin_4h_R1 5 KKVEEEDEEEEEEEEEEEEEEDE 23 2 O15347 O15347 HMGB3 High mobility group protein B3 0 0 ;;;; ;;;; 102.69 7.60E-05 549024000 22118.9 17108.6 18278.9 19682 19164.1 24545.1 20193.9 15610.5 22820.9 19480.9 FALSE FALSE TRUE 20368.16573 18587.39115 18956.33211 19600.5611 18935.58062 19454.16958 20760.48648 20370.06959 20317.50437 20157.85982 1.010432948 0.922091497 0.940394083 0.972353279 0.939364634 0.965091024 1.029895369 1.010527396 1.007919717 1 14.29905485 TQT(ph)PPLGQTPQLGLK ddPTM_HeLa_Curcumin_4h_R1 2 TQTPPLGQTPQLGLK 15 0 H0Y3P2;D3DQV9;P78344-2;P78344;E9PKF8 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 1 0 T(0.003)QT(0.997)PPLGQTPQLGLK;T(0.003)QT(0.997)PPLGQTPQLGLK ; 183.75 9.98E-05 892130000 8697.2 7764.4 7666.2 8545.4 7936.9 7739.5 5153.1 856.52 7661.5 7188.2 TRUE FALSE FALSE 8008.807443 8435.520139 7950.316116 8510.041399 7842.257651 6134.240458 5297.682117 1117.669005 6821.052618 7437.989415 1.076743592 1.134112953 1.06887973 1.144131959 1.054351817 0.824717557 0.712246525 0.150264936 0.917055973 1 12.86069698 -4.410051501 1.376962124 1.05483357 2.48E-18 0.924490024 0.078236952 0.162203563 0.328637259 0.010221364 0.218515988 3.89E-05 4.410051501 -1.05483357 down KLATPPAAQES(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 KLATPPAAQESSR 13 1 H0Y760;Q9Y4B4 H0Y760 RAD54L2 Helicase ARIP4 1 0 KLATPPAAQES(0.891)S(0.109)R 138.31 0.0017271 6471100 2873.7 2810 2572 3264.1 3273.7 3595.2 2432.9 1470.2 3502.9 3280.2 TRUE FALSE FALSE 2646.243613 3052.883879 2667.320583 3250.594019 3234.663266 2849.514994 2501.160626 1918.457212 3118.640634 3394.186706 0.779639967 0.899444887 0.785849694 0.957694523 0.953000983 0.839528064 0.736895416 0.565218528 0.918818234 1 11.72885021 -1 0.049904876 1.275832354 6.69E-15 0.378096036 0.09803782 435.4115267 1.657523639 10.14551346 43.09223455 0.1 1 -1.275832354 KLAVNMVPFPR ddPTM_HeLa_Curcumin_4h_R1 2 KLAVNMVPFPR 11 1 Q5JP53;P07437;Q5ST81;A0A075B736;Q5SQY0;A6NNZ2;CON__ENSEMBL:ENSBTAP00000025008;Q9H4B7;P04350;P68371;Q3ZCM7;Q9BVA1;Q13885;A0A0B4J269;Q13509;Q13509-2;Q9BUF5;K7ESM5 Q5JP53;P04350;P68371;Q9BVA1;A0A0B4J269;Q9BUF5 TUBB;TUBB8;TUBB1;TUBB4A;TUBB4B;TUBB2B;TUBB2A;TUBB3;TUBB6 Tubulin beta chain;Tubulin beta-8 chain-like protein LOC260334;Tubulin beta-1 chain;Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-8 chain;Tubulin beta-2B chain;Tubulin beta-2A chain;Tubulin beta-3 chain;Tubulin beta-6 chain 0 0 ; ; 137.46 7.89E-05 4388100 3754 1174.49 2651.7 1732.36 2604.3 6372.6 4064.5 3312.9 2679.7 2760 FALSE FALSE TRUE 3456.866939 1276.007682 2749.974335 1725.191953 2573.245423 5050.850926 4178.538931 4322.987959 2385.743614 2855.909795 1.210425814 0.446795513 0.962906581 0.604077887 0.901024755 1.768561085 1.463120067 1.513699056 0.835370788 1 11.4797347 -5.268033446 24.96843726 0.99126651 1.569926075 0.628171004 0.241194334 312.6984288 1184034.258 0.03802279 0.086919913 5.39E-06 5.268033446 0.578659565 (ac)ASASCSPGGALAS(ph)PEPGRK ddPTM_HeLa_Curcumin_4h_R1 1 ASASCSPGGALASPEPGRK 19 1 O15172 O15172 PSPHP1 Putative phosphoserine phosphatase-like protein 1 0 AS(0.001)ASCS(0.001)PGGALAS(0.999)PEPGRK 130.27 6.94E-10 9983300 1692.8 1539.7 1111.7 1903 1516.3 1954.1 985.49 261.37 1727.2 1396.1 TRUE FALSE FALSE 1558.813094 1672.784807 1152.90058 1895.12589 1498.219113 1548.797633 1013.140197 341.0605098 1537.730481 1444.614371 1.079051354 1.157945567 0.798068054 1.311855903 1.03710661 1.072118389 0.701322247 0.23609104 1.064457416 1 10.49646871 -4.409682997 2.157520839 1.052082959 0.144670048 0.815291321 0.123320672 0.136241454 0.888263722 0.016053007 0.209447281 3.89E-05 4.409682997 -0.907412911 down KLCY(ph)KGS(ph)TFHR ddPTM_HeLa_Curcumin_4h_R1 1 KLCYKGSTFHR 11 2 P30414;C9JMM5;A8K7K2 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase;Peptidyl-prolyl cis-trans isomerase 2 0 KLCY(0.941)KGS(0.529)T(0.529)FHR 105.2 0.010328 15380000 2546.1 1802.2 1765.1 2268.4 1677.1 2806.6 2085.6 2379.3 3251.9 2606.3 TRUE FALSE FALSE 2344.573498 1957.974138 1830.516159 2259.013962 1657.101678 2224.479523 2144.116323 3104.737617 2895.174706 2696.868731 0.869368787 0.72601759 0.678756121 0.837643277 0.614453962 0.824837893 0.795039187 1.151237945 1.073531934 1 11.39706959 -8.156809642 1.057359089 0.975297553 0.79715275 0.271153961 0.139517554 0.46664198 1.091354124 0.038204277 0.028188557 6.97E-09 8.156809642 -0.178144803 KLDEAVAEAHLGK ddPTM_HeLa_Curcumin_4h_R1 3 KLDEAVAEAHLGK 13 1 P23526-2;P23526 P23526-2 AHCY Adenosylhomocysteinase 0 0 ;; ;; 71.976 0.0052076 29082000 27587.2 22824 25819.9 25609.9 23543.9 30179.7 23250.3 24059.3 29026.3 26402.5 FALSE FALSE TRUE 25403.64401 24796.80486 26776.80821 25503.93302 23263.15437 23920.09002 23902.64084 31394.86981 25842.18751 27319.98491 0.929855712 0.907643432 0.980117972 0.933526614 0.851506853 0.875552827 0.874914131 1.149153995 0.945907825 1 14.73766907 -9.120546088 0.743079069 1.003246851 0.930618957 0.005006664 0.081141072 1.472207839 1.38048005 0.063805276 0.015862151 7.58E-10 9.120546088 -0.072627894 KLDEK(ac)ENLSAK ddPTM_HeLa_Curcumin_4h_R1 1 KLDEKENLSAK 11 2 U3KQ93;Q9UBT2-2;Q9UBT2 U3KQ93 UBA2 SUMO-activating enzyme subunit 2 0 1 KLDEK(1)ENLSAK 96.464 0.0031613 2193200 1796.2 1624.3 1565.1 1544 2136.1 2911.5 2056.6 1961.1 2579.1 1645.5 FALSE TRUE FALSE 1654.028875 1764.697254 1623.103983 1537.611337 2110.628403 2307.622081 2114.302661 2559.030362 2296.179183 1702.681003 0.971426164 1.036422707 0.953263694 0.903053088 1.239591209 1.355287383 1.241749134 1.502941748 1.348566866 1 10.73359246 -5.610674516 4.176944906 0.982692142 1.347607786 0.534496566 0.134615893 0.052146092 1.703886361 0.009321328 0.019354036 2.45E-06 5.610674516 0.364915644 KLDELYGTWR ddPTM_HeLa_Curcumin_4h_R1 1 KLDELYGTWR 10 1 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 0 121.36 0.006346 41965000 4557.1 2788.6 4074.7 3528.6 4086.2 4936.7 4052.4 4360.4 3708.5 3990.9 FALSE FALSE TRUE 4196.400726 3029.634158 4225.711966 3513.999588 4037.474734 3912.772772 4166.099438 5689.865887 3301.686828 4129.583478 1.016180142 0.733641583 1.023278011 0.850933177 0.977695391 0.947498166 1.008842528 1.377830456 0.799520544 1 12.01178056 -4.262261524 4.067224611 0.972835733 1.412513012 0.604898579 0.103904719 0.10886962 3.831758769 0.01231259 0.139863097 5.47E-05 4.262261524 0.439677279 KLDPAQS(ph)ASRENLLEEQGSIALR ddPTM_HeLa_Curcumin_4h_R1 1 KLDPAQSASRENLLEEQGSIALR 23 2 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 1 0 KLDPAQS(0.708)AS(0.292)RENLLEEQGSIALR 55.631 0.0085716 14073000 1707.3 1726.6 1431.1 1672.6 1571 1625.6 1417.1 2172.4 2384.1 1736.7 TRUE FALSE FALSE 1572.165403 1875.83961 1484.137825 1665.679224 1552.266851 1288.432236 1456.860012 2834.75476 2122.570195 1797.050196 0.874858926 1.043843747 0.82587444 0.926896326 0.863786028 0.716970644 0.810695225 1.577448847 1.181141295 1 10.81141499 -4.25612791 24.94083699 0.911483849 1.577449136 0.71452161 0.125397821 183.5801803 862001.3559 0.014054332 0.160391241 5.54E-05 4.25612791 0.665965287 KLDPEEEDDS(ph)FNNYEVQSEAK ddPTM_HeLa_Curcumin_4h_R1 1 KLDPEEEDDSFNNYEVQSEAK 21 1 A0A087WWW8;Q9Y6J0-2;Q9Y6J0 A0A087WWW8 CABIN1 Calcineurin-binding protein cabin-1 1 0 KLDPEEEDDS(0.993)FNNY(0.007)EVQSEAK 81.807 0.00049851 6610300 3825.7 3068.4 3570.2 3727.2 3262.6 3471.6 3227.1 2044.3 3615 3525.6 TRUE FALSE FALSE 3522.891808 3333.618823 3702.514753 3711.777834 3223.695626 2751.551027 3317.643741 2667.597659 3218.443544 3648.114338 0.965674725 0.913792309 1.014911927 1.017451069 0.883660798 0.754239251 0.909413312 0.73122644 0.882221128 1 11.83293523 -5.559428112 4.441800806 0.981955603 0.809821908 0.595877487 0.060768448 0.077594288 3.480894367 0.007011396 0.014768665 2.76E-06 5.559428112 -0.172133696 KLDPELHLDIK ddPTM_HeLa_Curcumin_4h_R1 1 KLDPELHLDIK 11 1 B4DY09;Q12905 B4DY09 ILF2 Interleukin enhancer-binding factor 2 0 0 59.84 0.010406 1434100 3947.9 3777 3637.1 3725 3896.8 4438.1 3677.3 3328.1 3927.9 3558.7 FALSE FALSE TRUE 3635.419549 4103.46705 3771.894126 3709.586937 3850.333205 3517.588032 3780.475141 4342.822369 3497.019197 3682.36456 0.987251395 1.114356545 1.024313064 1.007392635 1.045614344 0.955252522 1.026643364 1.179356986 0.949666754 1 11.84641675 -4.272749627 4.27458988 1.006743669 1.190863977 0.560260448 0.044474033 0.102220521 4.289776714 0.005703325 0.056071024 5.34E-05 4.272749627 0.184120308 KLDPGSEETQTLVR ddPTM_HeLa_Curcumin_4h_R1 1 KLDPGSEETQTLVR 14 1 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 0 103.83 0.0008806 13588000 4936.4 3698.4 4445.1 4541 4427.6 5311.9 4135.8 4240.6 4397.4 3996.7 FALSE FALSE TRUE 4545.678731 4018.073216 4609.839316 4522.210545 4374.803762 4210.152063 4251.839417 5533.539419 3915.016222 4135.585028 1.099162199 0.971585202 1.114676469 1.093487503 1.057843989 1.018030589 1.028110748 1.338030625 0.946665634 1 12.01387571 -4.259024846 24.96870956 1.048195779 1.338030728 0.735465494 0.053828822 78.07126784 807283.7941 0.006711701 0.060197981 5.51E-05 4.259024846 0.28983495 KLDVEEPDS(ph)ANSSFYSTR ddPTM_HeLa_Curcumin_4h_R1 1 KLDVEEPDSANSSFYSTR 18 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 KLDVEEPDS(0.984)ANS(0.014)S(0.001)FYSTR 115.02 0.00022617 21225000 2931.2 2207.6 2439.5 2251.6 2633 4222.5 3310.6 1499.1 2627.1 2097.1 TRUE FALSE FALSE 2699.192427 2398.415107 2529.910016 2242.283476 2601.603195 3346.705903 3403.486526 1956.168689 2338.913703 2169.974069 1.243882342 1.105273626 1.165871082 1.033322706 1.198909808 1.542279215 1.568445713 0.901470998 1.077853296 1 11.08346209 -13.52287874 0.123738559 0.190626448 1.363715055 0.131612157 0.194166682 112.8452178 1.001754437 22.86418717 0.846745925 3.00E-14 13.52287874 1.173088608 KLEAAEDIAYQLSR ddPTM_HeLa_Curcumin_4h_R1 1 KLEAAEDIAYQLSR 14 1 P35232 P35232 PHB Prohibitin 0 0 103.66 0.0057668 12858000 1568.8 1590.5 1894 1492.8 1433.9 2332.2 1497.7 1376.7 1890.6 1468 FALSE FALSE TRUE 1444.627825 1727.975733 1964.193306 1486.623189 1416.801679 1848.475431 1539.721431 1796.449492 1683.20591 1519.012891 0.951030655 1.137564891 1.293072177 0.978677138 0.932712084 1.216892524 1.013632893 1.182642691 1.10809192 1 10.5689184 -7.263600301 24.88005305 0.976875586 1.103868078 0.077531457 0.112890919 191.1776947 2201142.862 0.017551708 0.02060837 5.45E-08 7.263600301 0.126992492 KLEEEEDGK(ac)LK ddPTM_HeLa_Curcumin_4h_R1 1 KLEEEEDGKLK 11 2 P11387 P11387 TOP1 DNA topoisomerase 1 0 1 KLEEEEDGK(1)LK 81.565 0.0091214 2002700 1076.1 830.58 1140.8 1291 1607.4 1841.8 1453.5 1059.7 1591 889.95 FALSE TRUE FALSE 990.9255495 902.3716342 1183.079052 1285.658184 1588.232805 1459.789919 1494.281298 1382.797652 1416.47128 920.8756963 1.076068739 0.979906015 1.284732626 1.396125654 1.724698362 1.585219291 1.62267427 1.501611626 1.53817859 1 9.846862618 -6.329871586 1.724852982 1.032016438 1.604830405 0.53255182 0.176309414 0.061321158 0.356905718 0.011522532 0.020082402 4.68E-07 6.329871586 0.572813967 KLEEEGEQFVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 KLEEEGEQFVKK 12 2 H0YF61;P22307-6;P22307-2;P22307-4;P22307-7;P22307-8;P22307 H0YF61 SCP2 Non-specific lipid-transfer protein 0 1 KLEEEGEQFVK(1)K 141.37 2.59E-05 4660500 1269.5 1272.2 1252.2 1053.3 1381.2 1794.2 1546.3 1106.4 1629.7 1166.2 FALSE TRUE FALSE 1169.017735 1382.163299 1298.607634 1048.941724 1364.730092 1422.062695 1589.685016 1443.736267 1450.925987 1206.725363 0.968752105 1.145383483 1.076141824 0.869246438 1.130936776 1.178447672 1.317354441 1.196408322 1.202366364 1 10.23688166 -5.390797616 2.563642673 0.998715195 1.246565073 0.353954572 0.10055361 0.128061069 1.625295584 0.011139273 0.028646422 4.07E-06 5.390797616 0.247849878 KLEGNSPQGS(ph)NQGVK ddPTM_HeLa_Curcumin_4h_R1 2 KLEGNSPQGSNQGVK 15 1 P61006 P61006 RAB8A Ras-related protein Rab-8A 1 0 KLEGNS(0.001)PQGS(0.999)NQGVK;KLEGNSPQGS(1)NQGVK ; 121.77 0.00055771 21203700 5027.9 4440.3 4926 6157 5103.2 10220.2 7906.6 6750.6 7683.4 5465.4 TRUE FALSE FALSE 4629.93641 4824.099746 5108.561893 6131.523965 5042.347673 8100.415315 8128.437916 8808.826864 6840.550243 5655.322243 0.818686577 0.853019428 0.903319329 1.084204171 0.891611027 1.432352564 1.437307649 1.557617141 1.209577447 1 12.46539352 -5.232807664 5.043238517 0.918167035 1.480158382 0.787215262 0.119812561 0.045497322 3.209844857 0.013175864 0.033567186 5.85E-06 5.232807664 0.561991347 KLEKEEEEGISQES(ph)S(ph)EEEQ ddPTM_HeLa_Curcumin_4h_R1 2 KLEKEEEEGISQESSEEEQ 19 2 P17096;P17096-2 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 2 0 KLEKEEEEGIS(0.012)QES(0.994)S(0.994)EEEQ;KLEKEEEEGIS(0.026)QES(0.987)S(0.987)EEEQ ; 63.918 0.012073 448140000 8542.7 7127.1 6774.8 8710.9 7605.1 10720.2 7992.2 8903.3 10225.5 8604.5 TRUE FALSE FALSE 7866.536281 7743.134766 7025.880048 8674.856604 7514.41415 8496.709678 8216.439622 11617.87518 9103.788233 8903.505735 0.883532455 0.869672576 0.78911389 0.974319202 0.843983749 0.954310575 0.922831957 1.304865244 1.022494791 1 13.12015779 -4.261391675 22.02338602 0.923294656 1.304865584 0.736909413 0.069311717 0.296031234 134084.0307 0.009787233 0.075450923 5.48E-05 4.261391675 0.381570928 VDVEVPDVS(ph)LEGPEGK ddPTM_HeLa_Curcumin_4h_R1 1 VDVEVPDVSLEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VDVEVPDVS(1)LEGPEGK 140.49 0.00039417 16908000 4681.7 3385.9 4146.4 4098 3635.5 5229.2 4302.5 10352 3950.4 3219.3 TRUE FALSE FALSE 4311.138505 3678.562109 4300.069232 4081.043562 3592.149037 4144.604975 4423.21657 13508.27715 3517.051003 3331.170435 1.294181306 1.104285169 1.290858368 1.225108004 1.078344416 1.244188808 1.327826557 4.055114383 1.055800378 1 11.70181345 -4.259112272 4.494228792 1.160633328 4.254020252 0.987702036 0.096400239 0.018430138 0.933595903 0.016919115 0.180282458 5.51E-05 4.259112272 3.093386924 up KLENCNYAVELGK(ac)HPAK ddPTM_HeLa_Curcumin_4h_R1 2 KLENCNYAVELGKHPAK 17 2 P13797;A0A0A0MSQ0;P13797-3;P13797-2 P13797 PLS3 Plastin-3 0 1 ; KLENCNYAVELGK(1)HPAK;KLENCNYAVELGK(1)HPAK 98.676 0.0015178 11901600 6156.1 7420.9 5070.1 5637.4 8665.4 15380.1 9785.3 9805.2 15969.4 6660.4 FALSE TRUE FALSE 5668.838189 8062.329529 5258.002366 5614.073933 8562.070765 12190.09389 10059.84918 12794.76034 14217.59677 6891.848404 0.822542496 1.169835588 0.762930648 0.81459626 1.242347519 1.768769882 1.459673602 1.856506352 2.062958431 1 12.75067525 -5.479957201 3.36967953 0.917136446 1.668525307 0.238383891 0.390206017 0.065192241 1.492324027 0.020658199 0.04763144 3.31E-06 5.479957201 0.751388861 KLENCNYAVELGKHPAK ddPTM_HeLa_Curcumin_4h_R1 1 KLENCNYAVELGKHPAK 17 2 P13797;A0A0A0MSQ0;P13797-3;P13797-2 P13797 PLS3 Plastin-3 0 0 61.409 0.0075961 4749700 4754.5 4363 4030.7 4377 3506.2 6180.2 4329.2 3881.5 5295.6 4890.8 FALSE FALSE TRUE 4378.176308 4740.118279 4180.081288 4358.889134 3464.390855 4898.356855 4450.665701 5064.951482 4714.685929 5060.754936 0.865123161 0.936642524 0.825979788 0.861312035 0.68456009 0.967910305 0.879446991 1.000829233 0.931617118 1 12.3051369 -9.223415408 0.704660239 1.010939137 0.872041882 0.12635587 0.08460494 0.981777575 0.770284124 0.081595353 0.016907191 5.98E-10 9.223415408 -0.138897254 KLESGGGGEGGEGT(ph)EEEDGAER ddPTM_HeLa_Curcumin_4h_R1 3 KLESGGGGEGGEGTEEEDGAER 22 1 Q96LA8 Q96LA8 PRMT6 Protein arginine N-methyltransferase 6 1 0 KLESGGGGEGGEGT(1)EEEDGAER;KLESGGGGEGGEGT(1)EEEDGAER;KLESGGGGEGGEGT(1)EEEDGAER ;; 173.49 2.49E-09 46579000 5674.9 5850.7 5969.1 5800.4 6054.9 6262 4751.6 3328.05 5142.6 5751 TRUE FALSE FALSE 5225.725677 6356.408438 6190.320097 5776.399482 5982.699272 4963.190613 4884.917108 4342.757125 4578.469646 5950.846822 0.878148242 1.068151917 1.040241882 0.970685291 1.005352591 0.834030981 0.820877642 0.729771284 0.769381196 1 12.53887927 -5.003013649 2.331188028 0.964159835 0.768374796 0.460030285 0.083720799 0.171947181 1.824003142 0.010070668 0.037385151 9.93E-06 5.003013649 -0.195785039 KLFVGGIKEDTEEHHLR ddPTM_HeLa_Curcumin_4h_R1 2 KLFVGGIKEDTEEHHLR 17 2 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 ; ; 107.11 0.00032413 79639000 11338.4 9350.6 9060.7 10713.9 8370.6 13368.5 10589.2 9301 13481.2 10997 FALSE FALSE TRUE 10440.95368 10158.8242 9396.497513 10669.56872 8270.786062 10595.72241 10886.30445 12136.83208 12002.34609 11379.14493 0.917551691 0.892758134 0.825764815 0.937642396 0.726837219 0.931152777 0.956689147 1.066585596 1.054766958 1 13.47410453 -8.676028252 0.842316739 0.994537512 0.90145436 0.218002129 0.085538979 0.790718073 1.123917012 0.039251833 0.017559011 2.11E-09 8.676028252 -0.093083152 KLFVGGLK ddPTM_HeLa_Curcumin_4h_R1 1 KLFVGGLK 8 1 Q13151 Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0 0 0 82.241 0.012158 0 4120.7 2959 3845.2 3201.9 3880.7 5084.9 4198.5 3473.1 3255.4 3111.4 FALSE FALSE TRUE 3794.542247 3214.762775 3987.706495 3188.651386 3834.425187 4030.234421 4316.29861 4532.032202 2898.290765 3219.520918 1.178604626 0.998522096 1.238602449 0.990411762 1.190992475 1.251811845 1.340664875 1.407672855 0.900224238 1 11.65263031 -1 0.317090474 1.061560394 4.62289162 0.64740428 0.095149356 23.51702665 0.300088316 0.029421808 49.0920746 0.1 1 3.561331226 KLGAGEGGEASVS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 3 KLGAGEGGEASVSPEK 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 KLGAGEGGEAS(0.005)VS(0.995)PEK;KLGAGEGGEAS(0.014)VS(0.986)PEK;KLGAGEGGEAS(0.007)VS(0.993)PEK ;; 180.93 2.30E-05 91319000 13012.1 11644.2 12229.9 12585.6 13816 13371.9 11695.4 9318.9 11720.9 10895.7 TRUE FALSE FALSE 11982.17855 12650.67276 12683.15085 12533.52412 13651.25322 10598.41721 12023.54145 12160.18971 10435.14659 11274.32476 1.062784584 1.122078087 1.1249588 1.111687341 1.21082668 0.940048955 1.066453353 1.078573659 0.925567323 1 13.46075341 -8.284031715 0.962586046 1.009628847 1.091456102 0.306159411 0.069573603 0.543621935 1.053964581 0.020974461 0.013778326 5.20E-09 8.284031715 0.081827255 KLGAGEGGEASVS(ph)PEKTSTTSK ddPTM_HeLa_Curcumin_4h_R1 2 KLGAGEGGEASVSPEKTSTTSK 22 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 KLGAGEGGEAS(0.043)VS(0.597)PEKT(0.119)S(0.119)T(0.044)T(0.057)S(0.021)K;KLGAGEGGEAS(0.038)VS(0.742)PEKT(0.1)S(0.038)T(0.053)T(0.02)S(0.008)K ; 61.694 0.0057752 772130000 5866.8 4584.4 4785.7 5171.4 4220.7 5630.9 4230.6 3848 6522.9 4594.4 TRUE FALSE FALSE 5402.436589 4980.655108 4963.062252 5150.002117 4170.370909 4462.987867 4349.29925 5021.237486 5807.354189 4754.055058 1.136384944 1.047664583 1.043963983 1.083286174 0.87722394 0.938774964 0.914860934 1.056200954 1.221558042 1 12.2149429 -5.775939517 24.9999727 1.063985462 0.943915586 0.456876387 0.072891075 160.0878133 276010.4857 0.009437834 0.017162703 1.68E-06 5.775939517 -0.120069876 KLGAGEGGEASVSPEKTSTT(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 KLGAGEGGEASVSPEKTSTTSK 22 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 KLGAGEGGEAS(0.023)VS(0.163)PEKT(0.149)S(0.149)T(0.195)T(0.258)S(0.064)K 48.968 0.014657 401090000 4106.7 3073.1 3215.9 3684.2 3349.8 4014.7 3403 2279.2 4002.4 3712.6 TRUE FALSE FALSE 3781.650362 3338.725071 3335.084083 3668.955757 3309.855823 3182.005965 3498.479021 2974.117588 3563.346734 3841.612574 0.984391395 0.869094685 0.868146909 0.955056161 0.861579808 0.82829955 0.910679813 0.774184677 0.927565356 1 11.90749632 -6.757145473 0.460240876 1.007126572 0.830926931 0.421394587 0.051252539 0.450011425 0.212916074 0.016609103 0.030781211 1.75E-07 6.757145473 -0.176199642 KLGDVS(ph)PTQIDVSQFGSFK ddPTM_HeLa_Curcumin_4h_R1 1 KLGDVSPTQIDVSQFGSFK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 KLGDVS(0.888)PT(0.112)QIDVSQFGSFK 84.318 0.0016039 970290000 6411.2 5796.7 6089 5752.8 6184.6 4973.4 5599.5 7059.9 5404.1 5007.6 TRUE FALSE FALSE 5903.746755 6297.740918 6314.663696 5728.996438 6110.852684 3941.860778 5756.6069 9212.43101 4811.28375 5181.613727 1.139364504 1.215401466 1.218667394 1.105639428 1.179333892 0.760739991 1.110967973 1.777907713 0.928529992 1 12.33918576 -4.26458989 5.975255769 1.078634193 1.796074051 0.709998971 0.13520921 0.051028289 8.676747476 0.017986257 0.148669454 5.44E-05 4.26458989 0.717439858 KLGDVS(ph)PTQIDVSQFGSFKEDTK ddPTM_HeLa_Curcumin_4h_R1 2 KLGDVSPTQIDVSQFGSFKEDTK 23 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 KLGDVS(0.499)PT(0.499)QIDVS(0.002)QFGSFKEDTK;KLGDVS(0.811)PT(0.188)QIDVS(0.001)QFGSFKEDTK ; 86.357 0.00023787 835822000 2782.48 3458.8 2204.94 2762.52 1965.93 3081.93 2253.05 3195.76 2929.06 2929.87 TRUE FALSE FALSE 2562.243772 3757.76326 2286.657016 2751.089424 1942.487569 2442.702977 2316.264519 4170.132513 2607.749446 3031.682764 0.845155635 1.239497517 0.754253394 0.907446339 0.640729166 0.805725126 0.764019424 1.375517439 0.860165673 1 11.56590308 -9.575441149 1.142200822 1.00463322 0.89615866 0 0.21907739 1.938766716 4.197455367 0.17948806 0.03500997 2.66E-10 9.575441149 -0.108474559 KLGPGRPLPTFPTSECT(ph)SDVEPDTR ddPTM_HeLa_Curcumin_4h_R1 1 KLGPGRPLPTFPTSECTSDVEPDTR 25 2 Q8TDD1-2;Q8TDD1;H0YHZ9 Q8TDD1-2 DDX54 ATP-dependent RNA helicase DDX54 1 0 KLGPGRPLPTFPTSECT(0.557)S(0.438)DVEPDT(0.005)R 75.174 0.00017403 108540000 2143 2011.1 2191.2 2309.3 1985.5 1395.7 998.89 1308 2647.2 2243.4 TRUE FALSE FALSE 1973.379289 2184.930523 2272.4078 2299.744728 1961.824209 1106.216087 1026.916165 1706.803179 2356.808783 2321.357983 0.850096927 0.941229461 0.978913126 0.990689392 0.845119203 0.476538343 0.442377338 0.73526065 1.015271578 1 11.18075331 -5.377495131 4.248779246 0.935892763 0.541728091 0.814152133 0.087113101 0.073256076 2.204253363 0.012916445 0.030028516 4.19E-06 5.377495131 -0.394164672 KLGPGRPLPTFPTSECTS(ph)DVEPDTR ddPTM_HeLa_Curcumin_4h_R1 1 KLGPGRPLPTFPTSECTSDVEPDTR 25 2 Q8TDD1-2;Q8TDD1;H0YHZ9 Q8TDD1-2 DDX54 ATP-dependent RNA helicase DDX54 1 0 KLGPGRPLPTFPT(0.001)SECT(0.106)S(0.891)DVEPDT(0.001)R 68.291 0.00025534 80929000 1478.8 1427.1 1483.1 1604.7 1289.4 1725.4 851.75 1039.9 1715.2 1381.6 TRUE FALSE FALSE 1361.75142 1550.452165 1538.064991 1598.060177 1274.024747 1367.532591 875.6478126 1356.960723 1527.046851 1429.610497 0.952533171 1.084527686 1.075862967 1.117829073 0.891169133 0.956577049 0.612507962 0.94918212 1.068155875 1 10.48140642 -4.933039816 9.596796088 0.995944406 0.780599082 0.458006237 0.101914996 0.228894741 30.79188422 0.013116361 0.039467576 1.17E-05 4.933039816 -0.215345324 KLLEDTLFPSSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 KLLEDTLFPSSKK 13 2 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 0 1 ; KLLEDTLFPSSK(1)K;KLLEDTLFPSSK(1)K 157.2 2.31E-05 7543200 4945.1 3933.6 4382.2 4633.5 3911.6 6441.8 4759.4 4598.6 5457.9 4208.3 FALSE TRUE FALSE 4553.690117 4273.602856 4544.608187 4614.327805 3864.956725 5105.698066 4892.935955 6000.691971 4859.182025 4354.538112 1.045734358 0.981413584 1.043648734 1.059659529 0.887569847 1.172500489 1.123640632 1.378031795 1.115889194 1 12.08830398 -3.939923611 1.049114232 1.017401101 1.780808743 0.696705163 0.06892243 1.05038835 0.580006588 0.00853176 1.048429473 0.000114836 3.939923611 0.763407642 KLLEEDVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 KLLEEDVKR 9 2 P12270 P12270 TPR Nucleoprotein TPR 0 1 KLLEEDVK(1)R 78.149 0.010933 2918900 2187.2 1904.9 1685.3 1813.5 2212.7 4473.5 2253.9 2255.3 2061.5 1968.7 FALSE TRUE FALSE 2014.080812 2069.551068 1747.758701 1805.996218 2186.314998 3545.645673 2317.138368 2942.930588 1835.358608 2037.112178 0.98869411 1.015923958 0.857958987 0.886547259 1.073242319 1.74052549 1.137462331 1.44465809 0.900960991 1 10.99230971 -5.47123781 10.6497307 0.978215238 1.410349552 0.693970948 0.146800107 0.330789588 67.31672934 0.018629616 0.041593485 3.38E-06 5.47123781 0.432134313 KLNVTEQEK(ac)IDK ddPTM_HeLa_Curcumin_4h_R1 1 KLNVTEQEKIDK 12 2 P06733;K7EM90;A0A2R8YEM5;A0A2R8Y879 P06733 ENO1 Alpha-enolase;Enolase 0 1 KLNVTEQEK(1)IDK 85.536 0.0072957 6193300 2768.2 3093.5 2157.8 2572.5 4492.4 7665.9 5559.1 6084.9 6937.8 2659 FALSE TRUE FALSE 2549.094049 3360.888356 2237.769966 2561.855677 4438.831064 6075.905928 5715.073384 7940.157999 6176.740698 2751.400052 0.926471615 1.221519333 0.813320464 0.931109845 1.613299041 2.208296072 2.077151005 2.885860961 2.244944603 1 11.42595021 -5.274468577 1.264205083 0.962593381 2.593336784 0.562738093 0.452844498 0.096095009 0.276373563 0.029052278 0.123950821 5.32E-06 5.274468577 1.630743403 KLPCDTPGQGLTCSGEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 KLPCDTPGQGLTCSGEKR 18 2 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 0 1 ; KLPCDTPGQGLTCSGEK(1)R;KLPCDTPGQGLTCSGEK(1)R 154.52 3.87E-05 5078600 3129.3 2766.4 2954 2864.3 2511.5 3639.9 2417.3 2025.65 3438.3 2703.5 FALSE TRUE FALSE 2881.612603 3005.515289 3063.477839 2852.448286 2481.552003 2884.94371 2485.122932 2643.26136 3061.127092 2797.446424 1.030086789 1.074378141 1.095097948 1.019661453 0.88707758 1.031277556 0.888354076 0.94488364 1.094257629 1 11.44989479 -5.861957547 8.43098276 1.026873777 0.941198364 0.51364673 0.051038742 0.184286451 13.87556802 0.007000345 0.012722767 1.37E-06 5.861957547 -0.085675413 KLPPPPGS(ph)PLGHSPTASPPPTAR ddPTM_HeLa_Curcumin_4h_R1 1 KLPPPPGSPLGHSPTASPPPTAR 23 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 0 KLPPPPGS(0.987)PLGHS(0.009)PT(0.003)AS(0.001)PPPTAR 102.91 0.00010806 0 1195.8 949.57 1127.6 1207.9 1436.6 1570.7 1578.3 1697.9 1277.6 1159.6 TRUE FALSE FALSE 1101.151168 1031.6466 1169.389848 1202.90203 1419.469483 1244.919115 1622.58285 2215.581894 1137.450476 1199.896014 0.917705498 0.859780004 0.974575992 1.002505231 1.182993749 1.037522502 1.352269556 1.846478252 0.947957543 1 10.22869367 -1 0.671615997 0.955132684 95.03818149 0.939523698 0.068658102 37.84892392 0.209018757 0.012046119 5328.588679 0.1 1 94.08304881 KLPVDSVFNKFEDEDSDDVPR ddPTM_HeLa_Curcumin_4h_R1 1 KLPVDSVFNKFEDEDSDDVPR 21 2 P49756 P49756 RBM25 RNA-binding protein 25 0 0 69.975 0.0012405 8854400 2406.3 1831.4 1888.9 1898 1628.1 2133.9 1366.5 1273.2 2169.1 2347 FALSE FALSE TRUE 2215.838816 1989.698055 1958.904296 1890.146579 1608.685971 1691.305086 1404.840312 1661.392819 1931.155157 2428.558075 0.912409235 0.819291939 0.806612086 0.77829993 0.662403748 0.696423571 0.578466839 0.684106687 0.795185907 1 11.24588427 -6.508665837 0.453839592 0.992727358 0.599048187 0.64408291 0.07023453 0.169375836 0.072380525 0.011504354 0.026921723 3.10E-07 6.508665837 -0.393679171 KLRGY(ph)Y(ph)NQSEAEDVWLR ddPTM_HeLa_Curcumin_4h_R1 1 KLRGYYNQSEAEDVWLR 17 2 A0A0G2JKJ1 A0A0G2JKJ1 2 0 KLRGY(0.977)Y(0.977)NQS(0.047)EAEDVWLR 50.376 0.0095162 0 689.16 532.37 651.04 535.8 518.9 464.95 397.35 497.13 518.37 540.82 TRUE FALSE FALSE 634.6122588 578.3856906 675.1681151 533.5830016 512.7124564 368.5141289 408.4985716 648.7026485 461.5061079 559.6134547 1.134018944 1.033545005 1.20649014 0.95348494 0.916190367 0.658515491 0.729965601 1.159197734 0.824687298 1 9.128286839 -5.857201059 2.765744693 1.07187583 0.836311726 0.192312451 0.156123703 0.208753829 3.235480973 0.020073914 0.039706473 1.39E-06 5.857201059 -0.235564104 RPAS(ph)PALLLPPCMLK ddPTM_HeLa_Curcumin_4h_R1 2 RPASPALLLPPCMLK 15 1 Q9HAW0-2;Q9HAW0 Q9HAW0-2 BRF2 Transcription factor IIIB 50 kDa subunit 1 0 RPAS(1)PALLLPPCMLK;RPAS(1)PALLLPPCMLK ; 97.384 0.0022771 46755000 12044.2 10241.6 11975 11203.2 10641.5 12415.3 6623.4 1879.14 12086 11242.6 TRUE FALSE FALSE 11090.88886 11126.83827 12418.80403 11156.84413 10514.60706 9840.226831 6809.234778 2452.081136 10760.19604 11633.27951 0.953375946 0.956466167 1.06752391 0.959045479 0.903838599 0.845868684 0.585323749 0.210781589 0.924949497 1 13.50597024 -4.407324762 1.232355745 0.980114327 3.35E-22 0.973918962 0.039229107 0.113115784 0.171942379 0.005522159 0.130942743 3.91E-05 4.407324762 -0.980114327 down KLS(ph)NPDIFSSTGK ddPTM_HeLa_Curcumin_4h_R1 2 KLSNPDIFSSTGK 13 1 Q6P0Q8;Q6P0Q8-2 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 0 KLS(1)NPDIFSSTGK;KLS(0.993)NPDIFS(0.007)STGK ; 193.98 8.31E-06 77894000 5101 3879.5 4223.1 4237.3 3926.7 6353.3 4618 3825.7 5732.6 4988 TRUE FALSE FALSE 4697.250467 4214.826693 4379.611801 4219.767175 3879.876667 5035.553964 4747.568651 4992.138319 5103.748122 5161.332629 0.910084818 0.816615978 0.848542831 0.817573189 0.751719943 0.975630583 0.919833886 0.967218871 0.988843093 1 12.33352789 -8.321946923 0.955664523 0.986868828 0.871337111 0.332604741 0.066873071 0.426634258 0.813150959 0.023528331 0.015018025 4.76E-09 8.321946923 -0.115531717 LQTTDNLLPMS(ph)PEEFDEVSR ddPTM_HeLa_Curcumin_4h_R1 3 LQTTDNLLPMSPEEFDEVSR 20 0 A0A669KB68;A0A669KB56;A0A669KBA4;A0A669KB53;P42224 A0A669KB68 STAT1 Signal transducer and activator of transcription 1-alpha/beta 1 0 LQTTDNLLPMS(1)PEEFDEVSR;LQTT(0.001)DNLLPMS(0.998)PEEFDEVSR;LQTTDNLLPMS(1)PEEFDEVSR ;; 136.61 4.51E-05 16507600 6657.3 4821.4 5535.2 5998.1 6004.2 7341.2 6701.9 13650.6 6156.1 5689.5 TRUE FALSE FALSE 6130.36768 5238.140332 5740.339381 5973.281451 5932.603836 5818.552368 6889.937277 17812.6051 5480.791232 5887.209702 1.041302755 0.889749236 0.975052643 1.014620126 1.007710637 0.988337882 1.170323061 3.025644746 0.930965858 1 12.5233683 -4.259087159 4.016356947 1.005976719 3.21010689 0.994106769 0.046911285 0.011640681 0.390541253 0.006289525 0.074573246 5.51E-05 4.259087159 2.204130171 up KLS(ph)SSSEPY(ph)EEDEFNDDQSIKK ddPTM_HeLa_Curcumin_4h_R1 2 KLSSSSEPYEEDEFNDDQSIKK 22 2 Q9H4L7-2;Q9H4L7;D6RAY8 Q9H4L7-2 SMARCAD1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 2 0 KLS(0.789)S(0.167)S(0.158)S(0.158)EPY(0.727)EEDEFNDDQS(0.001)IKK;KLS(0.648)S(0.212)S(0.071)S(0.071)EPY(0.997)EEDEFNDDQSIKK ; 83.317 0.00084235 48989000 4921.1 4119.4 4916.9 4665.8 4945.7 5400.1 4438.2 2703.4 5598.3 4883.3 TRUE FALSE FALSE 4531.589742 4475.46258 5099.124639 4646.494156 4886.725758 4280.058388 4562.723947 3527.654215 4984.180496 5052.994312 0.896812754 0.88570505 1.009129305 0.91955262 0.967095044 0.84703408 0.902974289 0.698131444 0.986381577 1 12.30292284 -3.451420592 0.878765643 0.947827775 7.25E-14 0.701637491 0.047856958 3.579247825 0.732195208 0.008136277 4.60026227 0.000353655 3.451420592 -0.947827775 KLS(ph)SSSEPYEEDEFNDDQSIKK ddPTM_HeLa_Curcumin_4h_R1 1 KLSSSSEPYEEDEFNDDQSIKK 22 2 Q9H4L7-2;Q9H4L7;D6RAY8 Q9H4L7-2 SMARCAD1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 1 0 KLS(0.367)S(0.093)S(0.093)S(0.367)EPY(0.079)EEDEFNDDQSIKK 85.376 0.00042315 7781600 1177 1078 1144.9 1417 1162 1641.8 795.41 720.67 1475.5 1255.8 TRUE FALSE FALSE 1083.839208 1171.177517 1187.331001 1411.136829 1148.143909 1301.272173 817.7270639 940.3989654 1313.641342 1299.438957 0.834082434 0.901294755 0.913725878 1.085958538 0.883568946 1.001410775 0.629292403 0.723696146 1.010929628 1 10.34367315 -4.758315518 24.99999814 0.931355515 0.676494205 0.675183448 0.07567701 38.68778618 309598.7282 0.011443627 0.039458424 1.74E-05 4.758315518 -0.25486131 KLS(ph)VPTS(ph)DEEDEVPAPKPR ddPTM_HeLa_Curcumin_4h_R1 1 KLSVPTSDEEDEVPAPKPR 19 2 Q5STZ8;Q8NE71;Q8NE71-2;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 2 0 KLS(0.92)VPT(0.348)S(0.732)DEEDEVPAPKPR 99.846 0.0007558 53321000 3483.5 2255.1 2738.8 3339.4 3252.7 3806.5 2587.2 1778.9 3906.5 3285.6 TRUE FALSE FALSE 3207.777299 2450.020795 2840.302337 3325.582448 3213.913677 3016.988992 2659.789869 2321.278421 3477.966724 3399.774355 0.94352653 0.720642178 0.835438485 0.978177402 0.945331466 0.887408597 0.782343059 0.68277426 1.022999282 1 11.73122328 -1 0.149812218 1.025488463 0.029186385 0.436526767 0.085145398 52.49438133 0.508753669 0.201965659 11.41180563 0.1 1 -0.996302077 KLSLGQY(ph)DNDAGGQLPFSK ddPTM_HeLa_Curcumin_4h_R1 1 KLSLGQYDNDAGGQLPFSK 19 1 Q68CZ2;Q68CZ2-2;E9PCX8 Q68CZ2 TNS3 Tensin-3 1 0 KLS(0.195)LGQY(0.804)DNDAGGQLPFSK 93.812 0.0013146 171010000 6011.1 3863.9 4804.1 4993.8 5241.8 6764.5 4726.8 3187.7 5840.8 4785.6 TRUE FALSE FALSE 5535.315092 4197.878299 4982.144172 4973.136979 5179.294959 5361.466448 4859.421286 4159.615056 5200.078853 4951.899244 1.117816583 0.84773096 1.006107743 1.004288806 1.045920909 1.082709115 0.98132475 0.840003976 1.050118065 1 12.27376625 KLSPT(ph)KEAFGEQPLQLTTKPDLLAWDPAR ddPTM_HeLa_Curcumin_4h_R1 1 KLSPTKEAFGEQPLQLTTKPDLLAWDPAR 29 3 O00257 O00257 CBX4 E3 SUMO-protein ligase CBX4 1 0 KLS(0.208)PT(0.792)KEAFGEQPLQLTTKPDLLAWDPAR 73.839 3.71E-05 35807000 2968.2 2247.4 2252 2722.5 2380.7 3678.4 2815.4 1873.4 2948.3 2817.6 TRUE FALSE FALSE 2733.263838 2441.655242 2335.461101 2711.235016 2352.311707 2915.458376 2894.392547 2444.591036 2624.878866 2915.51139 0.937490365 0.837470658 0.801046811 0.929934634 0.806826451 0.999981816 0.992756384 0.838477615 0.900315079 1 11.50953324 -7.927687617 1.448254247 0.983130481 0.891879219 0.067073013 0.072841512 0.371338784 1.616567212 0.015986348 0.014213062 1.18E-08 7.927687617 -0.091251263 KLSSNCSGVEGDVT(ph)DEDEGAEMSQR ddPTM_HeLa_Curcumin_4h_R1 2 KLSSNCSGVEGDVTDEDEGAEMSQR 25 1 Q9UPR0;H7C276;Q9UPR0-2;Q9UPR0-3 Q9UPR0 PLCL2 Inactive phospholipase C-like protein 2;Phosphoinositide phospholipase C 1 0 KLSSNCSGVEGDVT(0.976)DEDEGAEMS(0.024)QR;KLSS(0.001)NCS(0.004)GVEGDVT(0.992)DEDEGAEMS(0.003)QR ; 79.286 0.00014971 8617500 8935.9 7268.1 7063.4 8088.2 7166.7 9500.8 7092.7 7471.4 9210.5 8148.9 TRUE FALSE FALSE 8228.614086 7896.322178 7325.175818 8054.733171 7081.241783 7530.226984 7291.702073 9749.395466 8200.131194 8432.073668 0.975870754 0.936462665 0.868727683 0.955249383 0.839798377 0.893045682 0.864757871 1.156227501 0.972492831 1 13.04167176 -7.301044696 2.696144334 0.989947898 0.92093082 0.069520695 0.083835846 0.422674503 5.885216589 0.013996821 0.016330874 5.00E-08 7.301044696 -0.069017078 KLSSSS(ph)EPY(ph)EEDEFNDDQSIKK ddPTM_HeLa_Curcumin_4h_R1 1 KLSSSSEPYEEDEFNDDQSIKK 22 2 Q9H4L7-2;Q9H4L7;D6RAY8 Q9H4L7-2 SMARCAD1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 2 0 KLS(0.123)S(0.093)S(0.094)S(0.807)EPY(0.87)EEDEFNDDQS(0.013)IKK 60.032 0.011939 14344000 1668.3 1512.6 1414.5 1205.8 1501.1 2002.9 1300.9 854.49 1772.8 1403.6 TRUE FALSE FALSE 1536.252295 1643.342404 1466.922614 1200.810719 1483.200363 1587.475963 1337.399753 1115.020067 1578.328275 1452.374996 1.05775182 1.131486296 1.010016434 0.826791099 1.02122411 1.09302072 0.920836393 0.767721884 1.086722286 1 10.50419828 -6.505788031 24.45576537 1.037511772 0.938033563 0.324529323 0.092567846 685.4679339 980863.3928 0.0144818 0.021793316 3.12E-07 6.505788031 -0.099478209 KLSSWDQAET(ph)PGHT(ph)PSLR ddPTM_HeLa_Curcumin_4h_R1 1 KLSSWDQAETPGHTPSLR 18 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 2 0 KLS(0.004)S(0.004)WDQAET(0.988)PGHT(0.705)PS(0.298)LR 43.035 0.017147 13943000 2277.6 2124.6 2158.3 2405.4 2062.3 3872.2 2366.3 1800.7 2917.3 3366.7 TRUE FALSE FALSE 2097.325557 2308.240957 2238.288497 2395.447092 2037.708419 3069.062071 2432.692009 2349.725141 2597.279489 3483.692574 0.602040941 0.662584573 0.642504598 0.687617245 0.584927739 0.880979594 0.698308464 0.67449268 0.745553585 1 11.7664016 -9.337892324 0.998913198 1.004943446 0.676992313 0.22662839 0.107696756 0.243316809 0.42426366 0.057968982 0.01434662 4.59E-10 9.337892324 -0.327951134 KLSSWDQAET(ph)PGHTPSLR ddPTM_HeLa_Curcumin_4h_R1 2 KLSSWDQAETPGHTPSLR 18 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 KLSSWDQAET(1)PGHTPSLR;KLSSWDQAET(0.959)PGHT(0.036)PS(0.005)LR ; 118.76 0.00020671 54600000 3039.1 2604.7 2382.7 3104 2912.2 5033.9 3758.9 1424.83 3911.3 3328.7 TRUE FALSE FALSE 2798.552028 2829.838662 2471.004958 3091.15647 2877.473917 3989.812396 3864.364617 1859.254108 3482.240176 3444.372077 0.812499917 0.821583324 0.717403609 0.897451379 0.835413205 1.158356968 1.12193588 0.539794792 1.010994195 1 11.75002528 -4.238106608 23.80859679 0.911860663 0.539793986 0.421440339 0.135785122 2888.744979 2947569.274 0.019938764 1.418936883 5.78E-05 4.238106608 -0.372066677 KLSVPT(ph)S(ph)DEEDEVPAPKPR ddPTM_HeLa_Curcumin_4h_R1 2 KLSVPTSDEEDEVPAPKPR 19 2 Q5STZ8;Q8NE71;Q8NE71-2;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 2 0 KLS(0.034)VPT(0.986)S(0.98)DEEDEVPAPKPR;KLS(0.305)VPT(0.848)S(0.848)DEEDEVPAPKPR ; 82.774 0.016655 37426800 8856.2 7565.1 8170.3 8512.6 8347.9 10372.9 7982.9 6093.2 10975.5 8786.9 TRUE FALSE FALSE 8155.222425 8218.993535 8473.098505 8477.377117 8248.356745 8221.443613 8206.878689 7950.98863 9771.515109 9092.244121 0.896942748 0.90395654 0.931903982 0.932374561 0.907186019 0.904226009 0.902624102 0.874480329 1.074708837 1 13.1504207 -9.319929126 0.729479889 1.009664287 0.906720858 0.739669523 0.029112817 0.291735573 0.236513555 0.018754966 0.003509157 4.79E-10 9.319929126 -0.102943428 KLSVPTS(ph)DEEDEVPAPKPR ddPTM_HeLa_Curcumin_4h_R1 2 KLSVPTSDEEDEVPAPKPR 19 2 Q5STZ8;Q8NE71;Q8NE71-2;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 0 KLSVPT(0.073)S(0.927)DEEDEVPAPKPR;KLSVPT(0.064)S(0.935)DEEDEVPAPKPR ; 98.76 0.00032608 527370000 7839.2 5723.5 6081.2 8022.2 7013 8569.1 6185.7 8307.1 8378.8 7247.3 TRUE FALSE FALSE 7218.719048 6218.213837 6306.574622 7989.006262 6929.374555 6791.772066 6359.254094 10839.89655 7459.666603 7499.143136 0.962605849 0.829189912 0.840972696 1.065322547 0.924022176 0.905673081 0.847997428 1.445484684 0.994735861 1 12.87251004 -4.253980155 24.97229249 0.952193653 1.445484922 0.800970831 0.076365265 315.8187554 1057285.143 0.01103037 0.154724636 5.57E-05 4.253980155 0.493291269 KLT(ph)FDPMT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 KLTFDPMTR 9 1 O95402 O95402 MED26 Mediator of RNA polymerase II transcription subunit 26 2 0 KLT(1)FDPMT(1)R 92.112 0.0058251 0 4434.3 3104.7 4515.9 3908.9 3575.6 4497.1 3238.4 3430.7 4033.3 3794.2 TRUE FALSE FALSE 4083.320476 3373.056434 4683.263227 3892.726008 3532.963305 3564.350767 3329.260788 4476.704637 3590.857081 3926.048168 1.04005868 0.859148001 1.192869529 0.991512544 0.899877728 0.907872399 0.847992853 1.140257186 0.914623797 1 11.93886216 -5.988066735 21.73956271 1.020013867 0.939703351 0.03381201 0.109040483 75.62091961 137757.3893 0.014115597 0.025560486 1.03E-06 5.988066735 -0.080310517 KLTAT(ph)PTPLGGMTGFHMQTEDR ddPTM_HeLa_Curcumin_4h_R1 1 KLTATPTPLGGMTGFHMQTEDR 22 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 KLT(0.14)AT(0.804)PT(0.056)PLGGMTGFHMQTEDR 53.798 0.0087932 0 526.2 591.28 406.07 437.14 701.47 634.3 549.08 212.52 713.13 550 TRUE FALSE FALSE 484.5507148 642.3876085 421.1193114 435.3312305 693.1054284 502.73903 564.485707 277.3163697 634.9014232 569.1124591 0.851414702 1.128753374 0.73995799 0.764930065 1.217870769 0.88337379 0.991870232 0.487278683 1.115599234 1 9.152569953 -4.257070595 24.20569548 0.937343658 0.487278398 0.460479079 0.15264051 185.0754024 1025367.159 0.018703449 0.194530647 5.53E-05 4.257070595 -0.45006526 KLTS(ph)DEEGEPS(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 KLTSDEEGEPSGK 13 1 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 2 0 KLT(0.433)S(0.572)DEEGEPS(0.995)GK 98.676 0.011848 6935000 4791.4 4130.2 4317.7 4851.8 4812.5 5541.2 4270.9 3517 5635 4064.8 TRUE FALSE FALSE 4412.155634 4487.196084 4477.71776 4831.724537 4755.114081 4391.892658 4390.729959 4589.31711 5016.854598 4206.051497 1.04900181 1.066842878 1.064589381 1.14875544 1.130541099 1.044184233 1.043907799 1.091122425 1.192770607 1 12.0382508 -7.884371837 0.728203004 1.007479168 1.087144143 0 0.066552185 0.384422028 0.450877312 0.011936705 0.009234251 1.31E-08 7.884371837 0.079664975 KLTS(ph)DEEGEPSGK ddPTM_HeLa_Curcumin_4h_R1 3 KLTSDEEGEPSGK 13 1 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 0 KLT(0.126)S(0.866)DEEGEPS(0.008)GK;KLT(0.024)S(0.96)DEEGEPS(0.015)GK;KLT(0.022)S(0.978)DEEGEPSGK ;; 213.52 3.38E-13 310717700 12093.6 11005.5 11157.7 11775.7 11535.3 13132.1 11615.4 10503.1 12121.2 11552.5 TRUE FALSE FALSE 11136.3788 11956.76638 11571.21418 11726.97527 11397.74908 10408.35443 11941.29686 13705.44684 10791.53469 11953.94852 0.931606723 1.000235727 0.967982601 0.981012697 0.953471488 0.870704305 0.998941634 1.146520484 0.902759007 1 13.54519961 -4.297203296 3.965696988 0.963412167 1.157463938 0.665448495 0.040809886 0.096301552 2.960695103 0.005459171 0.049733258 5.04E-05 4.297203296 0.194051771 KLVESLPQEIK ddPTM_HeLa_Curcumin_4h_R1 1 KLVESLPQEIK 11 1 B4DLN1;P52815 B4DLN1 MRPL12 "39S ribosomal protein L12, mitochondrial" 0 0 95.477 0.0012457 0 1518 1178.3 1003.1 1478.6 1306.1 1949 1724.1 1471.6 1633.8 1696.6 FALSE FALSE TRUE 1397.848698 1280.147002 1040.275768 1472.481945 1290.525611 1544.75543 1772.473606 1920.284066 1454.576228 1755.556724 0.7962424 0.729197174 0.592561752 0.83875498 0.735109036 0.879923394 1.009636192 1.093831968 0.828555528 1 10.7777129 -3.208211798 15.87461564 0.871165459 1.250357022 0 0.144981184 0 0 0.021407517 0 0.000619139 3.208211798 0.379191563 KLVIIEGDLER ddPTM_HeLa_Curcumin_4h_R1 2 KLVIIEGDLER 11 1 A0A087WWU8;P06753-2;P06753-5;P06753-3;P06753-6;P06753-4;P06753-7;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 0 ; ; 106.67 0.0060576 42198900 6777 6265.3 6628.6 7056 6072.7 8226.1 7117.6 7365.8 6010.7 6440.4 FALSE FALSE TRUE 6240.593299 6806.844614 6874.261747 7026.804142 6000.287019 6519.914133 7317.3007 9611.598512 5351.341248 6664.203421 0.936434995 1.021404088 1.031520395 1.054410212 0.90037573 0.978348607 1.098000802 1.442272678 0.802997884 1 12.70221672 -4.270858335 2.289239551 0.978968699 1.552195874 0.804838672 0.070656025 0.128930007 0.793764799 0.006711726 0.146584813 5.36E-05 4.270858335 0.573227175 KLVIIEGDLERTEER ddPTM_HeLa_Curcumin_4h_R1 1 KLVIIEGDLERTEER 15 2 A0A087WWU8;P06753-2;P06753-5;P06753-3;P06753-6;P06753-4;P06753-7;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 0 57.425 0.019692 19178000 3866.2 2899.2 2831 2777.9 2800.3 4438.4 3166.1 2038.9 3829 3586.6 FALSE FALSE TRUE 3560.18619 3149.793929 2935.91935 2766.405786 2766.908251 3517.825809 3254.932245 2660.551224 3408.96828 3711.234083 0.959299821 0.848718744 0.791089779 0.745413985 0.745549375 0.947885725 0.877048489 0.716891245 0.91855383 1 11.85768329 -7.237468397 2.391399859 0.983590633 0.808435514 0.507199839 0.067422058 0.151961077 1.661402638 0.011917345 0.014251096 5.79E-08 7.237468397 -0.175155119 KLVIIESDLER ddPTM_HeLa_Curcumin_4h_R1 2 KLVIIESDLER 11 1 P09493-3;H0YKX5;P09493-9;H7BYY1;Q6ZN40;P09493-2;P09493-8;F5H7S3;B7Z596;P09493-7;A0A494BZZ2;P09493-5;H0YL42;A0A494C0V8;P09493-4;P09493-10;A0A0S2Z4G6;P09493;H0YKJ4;H0YK48;P09493-6 P09493-3;P09493-4 TPM1 Tropomyosin alpha-1 chain 0 0 ; ; 92.943 0.0050688 2481300 2463.46 2112.62 2597.5 2033.9 2773.3 2729.8 2352.2 3191 2368.85 2104.59 FALSE FALSE TRUE 2268.474542 2295.225459 2693.765635 2025.484261 2740.230209 2163.608709 2418.196401 4163.92121 2108.993082 2177.724346 1.041672031 1.053955917 1.236963549 0.930092123 1.258299846 0.993518171 1.110423551 1.91205155 0.968438951 1 11.08860564 -4.26200425 4.393825724 1.047267118 1.973038894 0.859198078 0.102820593 0.04749735 2.216009509 0.012913482 0.136246016 5.47E-05 4.26200425 0.925771776 KLVILEGELERAEER ddPTM_HeLa_Curcumin_4h_R1 1 KLVILEGELERAEER 15 2 P67936;A0A2R8Y5V9;A0A2R8YGX3;A0A2R8YH90;A0A2R8YE05;P67936-2;K7ENT6;A0A2R8YEU4;A0A2R8YHD2;A0A5F9UN72 P67936 TPM4 Tropomyosin alpha-4 chain 0 0 63.292 0.015581 20123000 4180.1 3081.7 3033.3 3506.2 2410.5 4877.9 3532.3 3596.2 5218.1 4407.6 FALSE FALSE TRUE 3849.240674 3348.068416 3145.716766 3491.692273 2381.756362 3866.168555 3631.406831 4692.664825 4645.687485 4560.763772 0.843990364 0.734102572 0.689734642 0.765593758 0.522227522 0.847701996 0.796227784 1.028920826 1.018620502 1 12.15505973 -8.216611424 0.874380959 0.977525909 0.763244569 0.357624382 0.122383118 0.426923175 0.694501883 0.041490996 0.027284516 6.07E-09 8.216611424 -0.214281339 KLYDIDVAK ddPTM_HeLa_Curcumin_4h_R1 2 KLYDIDVAK 9 1 K7EMA7;H7BY10;K7EJV9;K7ERT8;A8MUS3;P62750 K7EMA7 RPL23A 60S ribosomal protein L23a 0 0 ; ; 120.06 0.0091129 33135000 8258.2 6364.1 7408.4 7661.2 6928.5 10578.9 8579.7 7479.1 8525.9 8079.4 FALSE FALSE TRUE 7604.554756 6914.184446 7682.961821 7629.499984 6845.882163 8384.716891 8820.423291 9759.44316 7590.630101 8360.158549 0.909618485 0.827039871 0.918997143 0.912602308 0.818869896 1.002937545 1.055054547 1.167375368 0.907952888 1 13.02931459 -4.60880093 1.987907838 0.932106737 1.165775916 0.676828353 0.057307307 0.237489536 1.562104261 0.00971871 0.078096867 2.46E-05 4.60880093 0.233669179 KLYGDADYLEER ddPTM_HeLa_Curcumin_4h_R1 2 KLYGDADYLEER 12 1 B4E1E0;P17812-2;P17812;A0A3B3IRI2 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 0 0 ; ; 118.61 0.0054331 80677000 7695.4 6635.2 7077 6877 7012.9 8583.2 7099.5 5908.2 8282.2 7018 FALSE FALSE TRUE 7086.30097 7208.717122 7339.279846 6848.544796 6929.275748 6802.947567 7298.692863 7709.582982 7373.663381 7261.874978 0.975822496 0.992679872 1.010659075 0.943082168 0.954199262 0.936803179 1.005070025 1.061651847 1.015393876 1 12.82612638 -9.460197509 1.053371679 1.000586294 0.982067583 0.04700678 0.035267737 2.007230325 3.773287418 0.029076736 0.006318384 3.47E-10 9.460197509 -0.018518711 KMANSS(ph)PVLSK ddPTM_HeLa_Curcumin_4h_R1 1 KMANSSPVLSK 11 1 Q9NXE8 Q9NXE8 CWC25 Pre-mRNA-splicing factor CWC25 homolog 1 0 KMANS(0.164)S(0.676)PVLS(0.16)K 73.386 0.016811 51224000 7222.7 5652.9 6023.9 7010.8 6216.3 8435.9 6621.5 3510.6 7686.8 6384.2 TRUE FALSE FALSE 6651.015674 6141.511487 6247.151033 6981.791167 6142.174682 6686.199248 6807.281469 4580.965779 6843.577271 6606.050475 1.006806669 0.92967977 0.945671102 1.056878265 0.929780162 1.012132631 1.030461619 0.693450012 1.035955946 1 12.68957228 -4.257345609 24.92816138 0.995174545 0.693449889 0.817391281 0.04263614 109.7961636 668553.3095 0.005315873 0.054766624 5.53E-05 4.257345609 -0.301724657 KMDTTTPLK(ac)GIPK ddPTM_HeLa_Curcumin_4h_R1 1 KMDTTTPLKGIPK 13 2 H0Y3X6;A0A0C4DFX9;Q9H3P2;C9JEM7;H7C2C7;C9JHL4 H0Y3X6 NELFA Negative elongation factor A 0 1 KMDTTTPLK(1)GIPK 82.202 0.0075225 1119100 1233 1293.2 1113.5 1226 1134.8 1357.3 952.7 813.74 1402.9 1172.8 FALSE TRUE FALSE 1135.406749 1404.978446 1154.76729 1220.927137 1121.268251 1075.78068 979.4301979 1061.84558 1249.00538 1213.554713 0.935604087 1.157738033 0.951557666 1.006075065 0.923953605 0.886470687 0.807075435 0.87498781 1.029212253 1 10.24502344 -5.34488202 1.973498909 0.985305229 0.842805022 0.538828189 0.062802364 0.225356687 1.687446099 0.009325942 0.027467778 4.52E-06 5.34488202 -0.142500207 KMEES(ph)DEEAVQAK ddPTM_HeLa_Curcumin_4h_R1 1 KMEESDEEAVQAK 13 1 I3VM54;Q9Y2K7-3;Q9Y2K7;Q9Y2K7-4;Q9Y2K7-5;Q9Y2K7-2 I3VM54 KDM2A Lysine-specific demethylase 2A 1 0 KMEES(1)DEEAVQAK 168.47 0.00029803 9527600 1781.6 1425.4 1441.4 1938.7 1630 1947.4 1468.4 1059.3 1922.5 1604 TRUE FALSE FALSE 1640.58448 1548.605225 1494.819552 1930.678173 1610.563315 1543.487288 1509.599352 1382.275694 1711.60656 1659.738881 0.988459389 0.933041482 0.900635377 1.163242119 0.970371504 0.929957903 0.909540271 0.832827205 1.031250506 1 10.69674057 -4.699009234 1.521827478 0.993317425 0.834166436 0.386939876 0.066632649 0.438162756 1.57528386 0.009312216 0.08168161 2.00E-05 4.699009234 -0.159150988 KMEGHDGIEK ddPTM_HeLa_Curcumin_4h_R1 1 KMEGHDGIEK 10 1 Q8TDB6 Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L 0 0 101.97 0.011078 22929000 2961.6 2428.5 3025.2 2580.9 2786.6 3298.5 2496.2 2338.3 2801.6 2804.1 FALSE FALSE TRUE 2727.186235 2638.408719 3137.316573 2570.22092 2753.371615 2614.353918 2566.236654 3051.236906 2494.271489 2901.542266 0.939909188 0.909312523 1.081258271 0.885811987 0.94893383 0.901022173 0.884438832 1.051591404 0.859636449 1 11.50260423 KMKDTDSEEEIREAFR ddPTM_HeLa_Curcumin_4h_R1 1 KMKDTDSEEEIREAFR 16 3 P0DP25;P0DP24;P0DP23;E7EMB3;A0A590UJC0;G3V226;G3V361;A0A590UJI2;Q96HY3 P0DP25 CALM2;CALM1 0 0 46.206 0.017421 47740000 2437.6 1685.2 1607.2 2009.4 1311.7 2355.2 1459.3 2219.5 3217.2 2636.3 FALSE FALSE TRUE 2244.661388 1830.861179 1666.764246 2001.085635 1296.058834 1866.704971 1500.24403 2896.215333 2864.281209 2727.911229 0.822849866 0.671158636 0.611003844 0.733559661 0.475110341 0.684298284 0.549960723 1.06169706 1.049990622 1 11.41358098 -7.86581293 0.879061676 0.966133489 0.666923367 0.422327868 0.151650195 0.340104034 0.564266277 0.040337712 0.033537245 1.36E-08 7.86581293 -0.299210122 KMLGEDS(ph)DEEEEMDTSER ddPTM_HeLa_Curcumin_4h_R1 6 KMLGEDSDEEEEMDTSER 18 1 A0A087X0M4;Q9BWU0;A0A087WWF4;H7C256 A0A087X0M4 SLC4A1AP Kanadaptin 1 0 KMLGEDS(1)DEEEEMDTSER;KMLGEDS(0.996)DEEEEMDT(0.002)S(0.002)ER;KMLGEDS(0.999)DEEEEMDT(0.001)S(0.001)ER;KMLGEDS(0.991)DEEEEMDT(0.004)S(0.005)ER;KMLGEDS(1)DEEEEMDTSER;KMLGEDS(1)DEEEEMDTSER ;;;;; 189.98 3.63E-09 470372000 14076.1 10395.7 11873.6 12161.8 12814.5 14415.5 11334.9 10848.7 13540.9 12206 TRUE FALSE FALSE 12961.96183 11294.25799 12313.64606 12111.47769 12661.69546 11425.5628 11652.92679 14156.41869 12055.49715 12630.15759 1.026270792 0.894229379 0.974940017 0.95893322 1.002497029 0.904625514 0.922627188 1.120842601 0.954500928 1 13.62458502 KMS(ph)DDEDDDEEEYGKEEHEK ddPTM_HeLa_Curcumin_4h_R1 2 KMSDDEDDDEEEYGKEEHEK 20 2 Q7KZ85;Q7KZ85-3 Q7KZ85 SUPT6H Transcription elongation factor SPT6 1 0 KMS(1)DDEDDDEEEYGKEEHEK;KMS(1)DDEDDDEEEYGKEEHEK ; 54.974 0.0087395 42826000 4757.6 4140.3 4418.3 3798.9 5222.6 5037.4 5171 4087.2 4027.7 4062 TRUE FALSE FALSE 4381.03094 4498.169083 4582.046085 3783.181158 5160.323906 3992.586457 5316.084343 5333.368465 3585.871387 4203.154198 1.042319823 1.070188928 1.090144655 0.900081458 1.227726527 0.949902447 1.264784515 1.268896694 0.853138195 1 12.03725667 -4.748438919 24.8329533 1.031500546 1.266840813 0.495133127 0.100150251 103.224042 197170.4073 0.010220299 0.037748417 1.78E-05 4.748438919 0.235340267 KMS(ph)GGSTMSSGGGNTNNSNSK ddPTM_HeLa_Curcumin_4h_R1 4 KMSGGSTMSSGGGNTNNSNSK 21 1 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 0 KMS(0.993)GGS(0.003)T(0.005)MSSGGGNTNNSNSK;KMS(0.919)GGS(0.059)T(0.021)MS(0.001)SGGGNTNNSNSK;KMS(0.961)GGS(0.028)T(0.011)MSSGGGNTNNSNSK;KMS(0.835)GGS(0.062)T(0.103)MSSGGGNTNNSNSK ;;; 157.73 7.31E-07 151658000 14169.4 11120.7 12136.5 12000.7 12996 14693.3 11820.3 10386.4 14599.9 12904.5 TRUE FALSE FALSE 13047.87704 12081.92376 12586.28937 11951.04428 12841.03119 11645.74395 12151.94581 13553.16555 12998.3275 13352.93041 0.977154575 0.904814403 0.942586307 0.895012848 0.961663904 0.872148928 0.910058349 1.014995595 0.973443813 1 13.70486877 -7.410912291 4.214835981 0.990318705 0.926456323 0.301544044 0.038016658 0.171024002 4.993437141 0.006240741 0.007048616 3.88E-08 7.410912291 -0.063862382 KMSGGS(ph)TMSSGGGNTNNSNSK ddPTM_HeLa_Curcumin_4h_R1 3 KMSGGSTMSSGGGNTNNSNSK 21 1 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 0 KMS(0.073)GGS(0.454)T(0.454)MS(0.019)S(0.001)GGGNTNNSNSK;KMS(0.045)GGS(0.388)T(0.388)MS(0.146)S(0.023)GGGNT(0.009)NNSNSK;KMS(0.138)GGS(0.719)T(0.138)MS(0.004)SGGGNTNNSNSK ;; 102.39 2.50E-05 16186500 8461.41 6850.62 6266.36 7658.03 7093.51 7952.94 6581.05 5117.96 8937.6 8027.4 TRUE FALSE FALSE 7791.68047 7442.757067 6498.596814 7626.343101 7008.924526 6303.410596 6765.696551 6678.402444 7957.167641 8306.351552 0.938038851 0.896032033 0.782364769 0.918133919 0.84380302 0.758866339 0.814520853 0.804011533 0.957961819 1 13.01999922 -7.052062224 0.435904595 1.000613442 0.787328976 0.704754103 0.042226014 0.332041624 0.155666168 0.018285661 0.025948484 8.87E-08 7.052062224 -0.213284466 KMT(ph)QQSFGY(ph)GTGLIQT ddPTM_HeLa_Curcumin_4h_R1 1 KMTQQSFGYGTGLIQT 16 1 Q4G0N0 Q4G0N0 GGTA1P "Inactive N-acetyllactosaminide alpha-1,3-galactosyltransferase" 2 0 KMT(0.807)QQS(0.5)FGY(0.692)GT(0.001)GLIQT 68.168 0.015166 8331500 3680.5 2829.7 3379.6 3062.2 4456.8 4296.3 3604.3 3589.2 3313.1 3293.9 TRUE FALSE FALSE 3389.184541 3074.286659 3504.850949 3049.529428 4403.655571 3405.198951 3705.426958 4683.530557 2949.661219 3408.36278 0.994373182 0.901983403 1.028309243 0.89471973 1.292014922 0.999071745 1.087157441 1.374129123 0.865418798 1 11.73486319 -1 0.639340964 0.993520047 30.20550986 0.527718009 0.10938942 106.4696788 0.662184485 0.016070394 4401.079208 0.1 1 29.21198981 KNDMDEPPPLDYGS(ph)GEDDGK ddPTM_HeLa_Curcumin_4h_R1 1 KNDMDEPPPLDYGSGEDDGK 20 1 Q12873-2;Q12873;Q12873-3;A0A5F9ZHX5;H7C2H0 Q12873-2 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 0 KNDMDEPPPLDYGS(1)GEDDGK 143.9 4.17E-05 15846000 2751.1 2242.8 2490.4 2781.8 2869.5 2173.7 2215.1 1810.3 2439 2650.6 TRUE FALSE FALSE 2533.347532 2436.657638 2582.696415 2770.289649 2835.283087 1722.850117 2277.249744 2362.252136 2171.447802 2742.708153 0.923666461 0.888413022 0.941659218 1.0100563 1.033753111 0.62815656 0.830292404 0.861284542 0.791716683 1 11.4213854 -5.27766191 24.99081935 0.963226343 0.778949277 0.418234879 0.088156551 402.8596313 620605.0506 0.010151506 0.022761779 5.28E-06 5.27766191 -0.184277066 KNGSTAVAESVAS(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 5 KNGSTAVAESVASPQK 16 1 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 KNGSTAVAESVAS(1)PQK;KNGSTAVAESVAS(1)PQK;KNGSTAVAESVAS(1)PQK;KNGSTAVAESVAS(1)PQK;KNGSTAVAESVAS(1)PQK ;;;; 159.26 0.0001442 519315000 38715.2 29069.3 32877.2 33802.8 33811.3 39482.6 33014.8 25035.18 36907.5 33503.43 TRUE FALSE FALSE 35650.85107 31581.92076 34095.65795 33662.93297 33408.12233 31293.4637 33941.10643 32668.29113 32858.83959 34667.6717 1.028360121 0.910990534 0.983500082 0.971017992 0.963667898 0.902669899 0.979041994 0.942327233 0.947823663 1 15.08130333 -7.277487298 24.95461399 1.013392281 0.952290182 0.167792095 0.033376083 426.931606 663879.9352 0.004429228 0.00507373 5.28E-08 7.277487298 -0.061102098 KNMS(ph)HEALT(ph)SS(ph)HSK ddPTM_HeLa_Curcumin_4h_R1 1 KNMSHEALTSSHSK 14 1 F8W9H2;Q96P56-3;Q96P56-2;Q96P56 F8W9H2 CATSPER2 Cation channel sperm-associated protein 2 3 0 KNMS(0.959)HEALT(0.513)S(0.513)S(0.774)HS(0.241)K 44.612 0.009557 0 276.21 268.05 407.32 492.84 328.11 346.55 185.18 263.78 369.18 369.41 TRUE FALSE FALSE 254.347687 291.2190476 422.4156375 490.8007587 324.1975025 274.6716236 190.3756524 344.2053077 328.6818776 382.24697 0.665401447 0.761860971 1.10508564 1.283988618 0.848136226 0.718571094 0.498043588 0.900478839 0.859867843 1 8.578361255 -5.26087482 4.671561214 0.887540964 0.681892714 0.203333815 0.191340596 0.293896031 18.11766725 0.031825243 0.078929545 5.48E-06 5.26087482 -0.20564825 KNPLPPSVGVVDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 KNPLPPSVGVVDKK 14 2 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 1 ; KNPLPPSVGVVDK(1)K;KNPLPPSVGVVDK(1)K 119.54 0.00010803 17993800 6277.4 8050.8 6323 6068.8 12927.8 14578.9 12586.3 11117.4 14379.4 6500.9 FALSE TRUE FALSE 5780.537166 8746.675278 6557.335942 6043.688914 12773.64443 11555.0718 12939.4377 14507.04408 12802.0158 6726.805791 0.859328684 1.300271711 0.974806787 0.898448551 1.898916785 1.717765037 1.923563442 2.156602187 1.903134443 1 12.71570589 -5.758636244 24.91857074 0.96382447 1.909419539 0.518149887 0.333206211 15.50612999 137839.4948 0.022937074 0.044291255 1.74E-06 5.758636244 0.945595069 KNQKPSQVNGAPGS(ph)PTEPAGQK ddPTM_HeLa_Curcumin_4h_R1 1 KNQKPSQVNGAPGSPTEPAGQK 22 2 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 0 KNQKPSQVNGAPGS(0.879)PT(0.121)EPAGQK 77.668 0.00031234 93056000 5779.5 4838 5574.8 6555 5614.6 6666.6 4613.6 3274 5439.7 5129.6 TRUE FALSE FALSE 5322.046476 5256.175162 5781.406992 6527.877147 5547.649562 5283.872012 4743.045199 4272.227528 4842.978519 5307.853218 1.002674011 0.99026385 1.089217571 1.229852612 1.045177652 0.995481939 0.893590121 0.804888032 0.912417567 1 12.37391276 -4.620625609 2.224190912 1.027159181 0.806489744 0.487641081 0.078373572 0.23979151 2.089506947 0.011146136 0.077272026 2.40E-05 4.620625609 -0.220669437 LNCSTS(ph)PEIFRK ddPTM_HeLa_Curcumin_4h_R1 1 LNCSTSPEIFRK 12 1 Q9BRS8 Q9BRS8 LARP6 La-related protein 6 1 0 LNCS(0.015)T(0.021)S(0.964)PEIFRK 102.33 0.012594 16956000 2273.6 1921.4 1864.2 2317.7 1846.9 1963.9 1258.6 407.51 2638 1999.2 TRUE FALSE FALSE 2093.642161 2087.477254 1933.288892 2308.109972 1824.876924 1556.565002 1293.912929 531.7579231 2348.618 2068.672051 1.012070598 1.009090471 0.934555524 1.115744746 0.882148972 0.75244648 0.625479968 0.25705279 1.135326404 1 11.01448924 -4.406074517 0.943521141 1.007868857 4.03E-17 0.925544545 0.069072638 0.236367844 0.184200849 0.008117963 0.229806769 3.93E-05 4.406074517 -1.007868857 down KNS(ph)ITEISDNEDDLLEYHRR ddPTM_HeLa_Curcumin_4h_R1 1 KNSITEISDNEDDLLEYHRR 20 2 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 0 KNS(0.927)IT(0.069)EIS(0.003)DNEDDLLEYHRR 47.113 0.013822 11368000 1036 1124.3 961.63 982.71 1373.6 965.72 923.15 862.09 1353.6 1251.2 TRUE FALSE FALSE 953.9995068 1221.479482 997.2688537 978.6438064 1357.220717 765.4187861 949.0511045 1124.937272 1205.113467 1294.679107 0.736861746 0.943461183 0.77028265 0.75589681 1.04830665 0.591203474 0.733039638 0.868892737 0.930820201 1 10.33837885 -9.439386752 1.008425768 1.007790229 0.799764738 0.210124465 0.120767106 0.604169908 1.030066198 0.095669402 0.02054191 3.64E-10 9.439386752 -0.208025491 KNS(ph)LRVEGDNIYVR ddPTM_HeLa_Curcumin_4h_R1 1 KNSLRVEGDNIYVR 14 2 O43491;H0Y5B0 O43491 EPB41L2 Band 4.1-like protein 2 1 0 KNS(1)LRVEGDNIYVR 78.529 0.0059404 78194000 4409 3268.7 3157.5 3937.3 3485.7 5859 6057.8 2231.7 4145.3 3448.2 TRUE FALSE FALSE 4060.022998 3551.231863 3274.519728 3921.008496 3444.135304 4643.777355 6227.765564 2912.135057 3690.570961 3568.024693 1.137890947 0.995293522 0.917740209 1.098929753 0.965277878 1.301498099 1.74543791 0.816175701 1.034345689 1 11.80090988 -5.201060308 6.850588788 1.046737341 1.336246437 0.223724987 0.218641039 0.243795369 23.22512114 0.027720206 0.071167531 6.29E-06 5.201060308 0.289509096 KNS(ph)SQDDLFPTSDTPR ddPTM_HeLa_Curcumin_4h_R1 1 KNSSQDDLFPTSDTPR 16 1 Q9H6T3-3;Q9H6T3-2;Q9H6T3 Q9H6T3-3 RPAP3 RNA polymerase II-associated protein 3 1 0 KNS(0.5)S(0.5)QDDLFPTSDTPR 108.96 0.0007996 19275000 6677.3 5722.5 5399.4 6696.4 6574.1 2800.1 3604.1 2945 5814.4 5359 TRUE FALSE FALSE 6148.784659 6217.127401 5599.506514 6668.692071 6495.708151 2219.327696 3705.221346 3842.916943 5176.574867 5545.224851 1.108843162 1.121167774 1.009788902 1.202600841 1.171405728 0.400223211 0.668182345 0.693013727 0.93351938 1 12.43703025 -5.268577207 24.99985397 1.073223546 0.595244015 0.819088278 0.105716903 152.8757426 535439.5273 0.014240635 0.032474605 5.39E-06 5.268577207 -0.477979532 KNS(ph)STDQGS(ph)DEEGSLQK ddPTM_HeLa_Curcumin_4h_R1 1 KNSSTDQGSDEEGSLQK 17 1 Q12789-3;Q12789 Q12789-3 GTF3C1 General transcription factor 3C polypeptide 1 2 0 KNS(0.962)S(0.031)T(0.008)DQGS(1)DEEGSLQK 110.57 0.00046773 28097000 4862.8 3818.3 5432.3 5006.9 5925.2 5246.4 3247.2 3438.7 3965.4 4334.2 TRUE FALSE FALSE 4477.904249 4148.336838 5633.625817 4986.182774 5854.54586 4158.237501 3338.307693 4487.1438 3530.405541 4484.813127 0.998459495 0.92497429 1.2561562 1.111792762 1.305415787 0.927181888 0.744358259 1.000519681 0.787191225 1 12.13083216 -5.010276385 24.92799773 1.042459425 0.863271716 0.195973801 0.153395011 506.6909662 1229119.083 0.018835377 0.052001474 9.77E-06 5.010276385 -0.179187709 KNS(ph)TGSGHSAQELPTIR ddPTM_HeLa_Curcumin_4h_R1 1 KNSTGSGHSAQELPTIR 17 1 I3L280;O94763-2;O94763-4;O94763-3;O94763 I3L280 URI1 Unconventional prefoldin RPB5 interactor 1 1 0 KNS(0.788)T(0.195)GS(0.017)GHSAQELPTIR 77.1 0.0054769 5172800 1275.8 1310 1039.7 1057.2 1581.3 1971.1 1023.1 878.13 2005 1150.3 TRUE FALSE FALSE 1174.819084 1423.230563 1078.232197 1052.825587 1562.44403 1562.271641 1051.805432 1145.867795 1785.056516 1190.272839 0.987016628 1.195717919 0.905869781 0.884524583 1.31267721 1.312532379 0.883667507 0.96269339 1.499703645 1 10.2170766 -5.793151347 24.99999705 0.996379698 1.115065727 0 0.216490447 312.0553432 246006.6995 0.022081515 0.040028752 1.61E-06 5.793151347 0.118686029 KNSSTDQGS(ph)DEEGSLQK ddPTM_HeLa_Curcumin_4h_R1 2 KNSSTDQGSDEEGSLQK 17 1 Q12789-3;Q12789 Q12789-3 GTF3C1 General transcription factor 3C polypeptide 1 1 0 KNS(0.001)ST(0.001)DQGS(0.998)DEEGS(0.001)LQK;KNSSTDQGS(1)DEEGSLQK ; 135.26 0.00016409 22101300 6112.4 4757.5 6240.9 5651.5 6077.8 6510.8 5937.9 3544.4 5406.9 5190.9 TRUE FALSE FALSE 5628.59709 5168.717101 6472.193244 5628.11559 6005.326205 5160.386688 6104.501493 4625.071244 4813.776597 5371.283389 1.047905441 0.962287172 1.204962162 1.047815798 1.118043076 0.960736255 1.13650706 0.861073771 0.896206037 1 12.39105112 -4.240063623 24.12863014 1.040786615 0.861073478 0.274985943 0.087932918 2851.623085 3218790.683 0.009745454 0.564209298 5.75E-05 4.240063623 -0.179713137 KNSTDLDS(ph)APEDPTS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 KNSTDLDSAPEDPTSPK 17 1 I3L2J0;A0A0A0MQR4;Q96RK0;I3L373;I3L135;I3L1Q4 I3L2J0 CIC Protein capicua homolog 2 0 KNS(0.007)T(0.009)DLDS(0.984)APEDPT(0.293)S(0.707)PK 92.805 0.001449 29479000 4113.3 3799.6 4535.5 4588.4 4319.6 4176.9 5087.8 5123.1 3992.9 4470.4 TRUE FALSE FALSE 3787.727965 4128.020493 4703.58962 4569.414417 4268.091591 3310.563857 5230.549975 6685.109606 3554.88886 4625.746067 0.818836121 0.892401017 1.016828324 0.987822148 0.922681775 0.715682143 1.130747321 1.445195977 0.76850065 1 12.17547036 -4.434196151 3.498258886 0.913488143 1.435806686 0.749165284 0.099090737 0.096290868 2.015275487 0.013722637 0.099529299 3.68E-05 4.434196151 0.522318543 RYT(ph)Y(ph)ERIDGRVR ddPTM_HeLa_Curcumin_4h_R1 1 RYTYERIDGRVR 12 3 Q8TD26 Q8TD26 CHD6 Chromodomain-helicase-DNA-binding protein 6 2 0 RY(0.207)T(1)Y(0.793)ERIDGRVR 68.515 0.017922 67552000 2706.5 2537.6 2842.2 2497.5 2429 2531.7 1527.9 442.26 2850.6 2377.1 TRUE FALSE FALSE 2492.277669 2756.938837 2947.534432 2487.166007 2400.035761 2006.596882 1570.768762 577.1030381 2537.896312 2459.704048 1.013242903 1.120841688 1.198328894 1.011164741 0.975741681 0.815787933 0.638600714 0.234622957 1.031789298 1 11.26426903 -4.405825181 1.12742768 1.031404007 8.22E-14 0.939712555 0.065610929 0.250387817 0.303404152 0.011226478 0.285734587 3.93E-05 4.405825181 -1.031404007 down KNTFTAWSDEES(ph)DY(ph)EIDDRDVNK ddPTM_HeLa_Curcumin_4h_R1 1 KNTFTAWSDEESDYEIDDRDVNK 23 2 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50 Q6PKG0 LARP1 La-related protein 1 2 0 KNTFTAWS(0.026)DEES(0.978)DY(0.995)EIDDRDVNK 90.882 0.00021499 35952000 3212.6 2732.1 3069.6 2990.6 2816.3 3799 2886.4 3192 3579.4 3241.1 TRUE FALSE FALSE 2958.31932 2968.25055 3183.362076 2978.22569 2782.717462 3011.044576 2967.384616 4165.226106 3186.748775 3353.727984 0.882098767 0.885060018 0.949201036 0.888034362 0.82973857 0.897820154 0.884801818 1.241968975 0.950210867 1 11.71154996 -4.257349169 24.9453457 0.922193329 1.241969104 0.816051702 0.047182235 165.4107688 1008764.885 0.008449415 0.086415699 5.53E-05 4.257349169 0.319775775 KPAAAAAPGTAEK ddPTM_HeLa_Curcumin_4h_R1 2 KPAAAAAPGTAEK 13 1 P50454;E9PR70;E9PPV6;E9PK86;E9PMI5;E9PQ34;E9PJH8;E9PIG2;E9PRS3;E9PNX1 P50454 SERPINH1 Serpin H1 0 0 ; ; 110.25 0.00061886 16268200 17257.2 14723.3 19077 16827 17741.7 19029.6 13568.7 11525.5 16163.9 15902.1 FALSE FALSE TRUE 15891.27441 15995.91645 19784.0104 16757.37433 17530.14181 15082.64645 13949.4012 15039.57189 14390.76061 16454.69679 0.965759176 0.972118578 1.202332115 1.018394599 1.065357936 0.916616492 0.847745867 0.913998725 0.874568568 1 14.00621182 -5.074705155 5.673024817 1.006578256 0.88084715 0.326787204 0.080301229 0.17639609 10.04092818 0.01029507 0.027170411 8.42E-06 5.074705155 -0.125731106 KPAAATVTK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 KPAAATVTKK 10 2 P16403 P16403 HIST1H1C Histone H1.2 0 1 ; KPAAATVTK(1)K;KPAAATVTK(1)K 110.31 5.11E-05 0 16889.7 11374.8 13338.9 14000 14018.4 16971.9 12317.4 8519.9 17401.7 12499 FALSE TRUE FALSE 15552.86242 12357.98703 13833.25137 13942.07171 13851.23974 13451.73663 12662.99309 11117.57829 15492.77705 12933.33932 1.202540352 0.955514019 1.069580796 1.077994736 1.070971649 1.040082247 0.979096951 0.859606171 1.197894578 1 13.6588072 -3.474056072 0.775549647 1.084576094 0.276109151 0.491170387 0.071094017 5.504667337 0.989334539 0.013318968 5.152651145 0.000335694 3.474056072 -0.808466943 KPAT(ph)PAEDDEDDDIDLFGS(ph)DNEEEDKEAAQLR ddPTM_HeLa_Curcumin_4h_R1 6 KPATPAEDDEDDDIDLFGSDNEEEDKEAAQLR 32 2 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;P29692-4;E9PQZ1;H0YE72 P29692 EEF1D Elongation factor 1-delta 2 0 KPAT(1)PAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPAT(1)PAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPAT(1)PAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPAT(1)PAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPAT(1)PAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPAT(1)PAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR ;;;;; 65.817 4.20E-05 292425400 23975.9 20982.9 24331 22050.5 26066.5 25643.7 23503.7 20308.6 20800.11 19074 TRUE FALSE FALSE 22078.18222 22796.56838 25232.72826 21959.26087 25755.67401 20324.90756 24163.15057 26500.59865 18518.38997 19736.82008 1.118629147 1.15502742 1.278459659 1.112603793 1.304955606 1.029796465 1.224267661 1.342698497 0.938266139 1 14.26860195 -13.52287875 0.077052354 0.261676213 1.426268063 0.541923923 0.087554439 115.1964408 0.683801451 14.48480378 1.732512548 3.00E-14 13.52287875 1.16459185 KPATPAEDDEDDDIDLFGS(ph)DNEEEDK ddPTM_HeLa_Curcumin_4h_R1 1 KPATPAEDDEDDDIDLFGSDNEEEDK 26 1 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;P29692-4;E9PQZ1;H0YE72 P29692 EEF1D Elongation factor 1-delta 1 0 KPATPAEDDEDDDIDLFGS(1)DNEEEDK 105.25 1.09E-07 16018000 2874 2946.4 3357.8 3521.2 3775.5 2743.5 3234.9 3179.9 2944.8 2793.6 TRUE FALSE FALSE 2646.519867 3201.073687 3482.243022 3506.630207 3730.479628 2174.467174 3325.662588 4149.436872 2621.762808 2890.677392 0.915536225 1.107378394 1.204646022 1.213082517 1.290520913 0.752234469 1.150478638 1.435454846 0.906971776 1 11.49719189 -7.118080281 4.427225326 0.960466971 1.160865441 0.282417006 0.164551885 0.248890679 7.958377392 0.027373363 0.033843902 7.62E-08 7.118080281 0.20039847 KPATPAEDDEDDDIDLFGS(ph)DNEEEDKEAAQLR ddPTM_HeLa_Curcumin_4h_R1 6 KPATPAEDDEDDDIDLFGSDNEEEDKEAAQLR 32 2 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;P29692-4;E9PQZ1;H0YE72 P29692 EEF1D Elongation factor 1-delta 1 0 KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR ;;;;; 128.33 1.38E-13 2117588400 19838.84 16933.94 20173.81 17453.53 23204.8 21419.2 18985.35 19707.9 16578.7 16011.84 TRUE FALSE FALSE 18268.57488 18397.63432 20921.46915 17381.31192 22928.09792 16976.61648 19518.02782 25716.74799 14760.05809 16568.25025 1.10262548 1.110415043 1.262744637 1.049073478 1.383857533 1.024647517 1.178037966 1.552170422 0.890864024 1 14.01613363 -1 0.202753061 1.007027785 2.784930947 0.473591606 0.135540852 35.79478345 0.413292797 0.111685991 20.46457939 0.1 1 1.777903162 KPATPAEDDEDDDIDLFGS(ph)DNEEEDKEAAQLREER ddPTM_HeLa_Curcumin_4h_R1 9 KPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREER 35 3 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;P29692-4;E9PQZ1;H0YE72 P29692 EEF1D Elongation factor 1-delta 1 0 KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLREER;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLREER;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLREER;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLREER;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLREER;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLREER;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLREER;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLREER;KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLREER ;;;;;;;; 101.39 6.52E-12 4838794000 26250.69 23145.92 23347.34 25041.98 22542.44 29547.66 23575.97 23938.58 28753.64 26058.38 TRUE FALSE FALSE 24172.92019 25146.55019 24212.61296 24938.36292 22273.63613 23419.14225 24237.44827 31237.34284 25599.43763 26963.90677 0.896491758 0.932600398 0.897963829 0.924879438 0.826053744 0.868536687 0.898884886 1.158487274 0.94939646 1 14.71874192 -9.357784396 1.004586409 1.001534468 0.917154327 0.031345418 0.085195472 0.978149045 1.714909369 0.060599868 0.014657478 4.39E-10 9.357784396 -0.084380141 KPATPAEDDEDDDIDLFGSDNEEEDKEAAQLR ddPTM_HeLa_Curcumin_4h_R1 1 KPATPAEDDEDDDIDLFGSDNEEEDKEAAQLR 32 2 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;P29692-4;E9PQZ1;H0YE72 P29692 EEF1D Elongation factor 1-delta 0 0 129.04 2.01E-13 4690400 1177.9 1067.4 1108.2 1079.7 1357.8 1347.4 1079.6 1367.5 908.66 843.98 FALSE FALSE TRUE 1084.667972 1159.6613 1149.270867 1075.232487 1341.609122 1067.934052 1109.89067 1784.444455 808.9822714 873.3082422 1.242021911 1.327894601 1.315996817 1.231217611 1.536237788 1.222860383 1.270903693 2.043315714 0.926342192 1 9.770347146 -1 0.17791873 1.006759306 3.835714698 0.576905493 0.189918596 33.21172418 0.358229766 0.237826293 25.46954163 0.1 1 2.828955393 KPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREER ddPTM_HeLa_Curcumin_4h_R1 1 KPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREER 35 3 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;P29692-4;E9PQZ1;H0YE72 P29692 EEF1D Elongation factor 1-delta 0 0 33.453 0.015928 4223800 1269.8 1048.7 1230.7 1096.8 1165.8 1181.9 914.1 1240.4 1330 1438.4 FALSE FALSE TRUE 1169.29399 1139.344955 1276.310825 1092.261732 1151.898596 936.7606172 939.7471858 1618.59225 1184.102327 1488.384293 0.78561296 0.765491117 0.857514306 0.733857336 0.773925526 0.629380881 0.631387465 1.087482754 0.79556223 1 10.53953136 -9.14193938 0.530081855 1.03791161 0.764450426 0.002383277 0.137532946 1.172173696 0.489245236 0.161822893 0.030113814 7.21E-10 9.14193938 -0.273461184 (ac)AS(ph)PSRQPPPGGSGLLQGSR ddPTM_HeLa_Curcumin_4h_R1 1 ASPSRQPPPGGSGLLQGSR 19 1 Q96S90 Q96S90 LYSMD1 LysM and putative peptidoglycan-binding domain-containing protein 1 1 0 AS(0.569)PS(0.431)RQPPPGGSGLLQGSR 66.708 0.00047455 36151000 702 550.97 559.16 760.47 602.09 1621.9 1594.3 7634 884.47 1758.5 TRUE FALSE FALSE 646.4359593 598.5933917 579.8829615 757.3233766 594.91047 1285.499657 1639.031767 9961.571457 787.4458538 1819.607744 0.355261161 0.328968369 0.318685697 0.416201447 0.326944349 0.706470755 0.900761042 5.474570819 0.432755827 1 10.82941176 -4.25893896 4.372981859 0.595574026 5.835642354 0.977257069 0.226496494 0.029011515 1.325395778 0.043049347 0.470753462 5.51E-05 4.25893896 5.240068327 up SSSYS(ph)EANEPDLQMANGGK ddPTM_HeLa_Curcumin_4h_R1 1 SSSYSEANEPDLQMANGGK 19 0 H0Y3A3;A0A3B3ITG3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-2;Q5VWQ8-5;Q5VWQ8 H0Y3A3 DAB2IP Disabled homolog 2-interacting protein 1 0 S(0.001)S(0.001)S(0.006)YS(0.993)EANEPDLQMANGGK 180.02 3.77E-07 4125500 1057.2 691.38 932.01 1115.2 1118.9 1139.1 1289.3 2876.9 1208.9 1009.2 TRUE FALSE FALSE 973.5215044 751.1398065 966.5511105 1110.585598 1105.557848 902.8378197 1325.474288 3754.053566 1076.286695 1044.269625 0.932251098 0.719296807 0.925576199 1.063504646 1.058690037 0.8645639 1.26928358 3.594908323 1.030659773 1 10.02827854 -4.258932698 3.446062149 0.955629863 3.933708832 0.984618011 0.098575472 0.025022062 0.500805129 0.013815003 0.194910898 5.51E-05 4.258932698 2.97807897 up KPEDVLDDDDAGS(ph)APLK ddPTM_HeLa_Curcumin_4h_R1 1 KPEDVLDDDDAGSAPLK 17 1 A0A087WUV8;P35613-3;P35613-4;P35613-2;P35613 A0A087WUV8 BSG Basigin 1 0 KPEDVLDDDDAGS(1)APLK 62.099 0.014604 7050200 1223.5 1357.1 1335.5 1446.4 1475.1 1819 1252.1 621.5 1417.3 1212.5 TRUE FALSE FALSE 1126.658684 1474.401677 1384.994805 1440.41518 1457.510396 1441.718896 1287.230556 810.992489 1261.825736 1254.634285 0.897997686 1.175164504 1.103903202 1.148075736 1.161701393 1.149114856 1.025980696 0.646397519 1.00573191 1 10.29305118 -7.277695646 24.86595255 0.951832241 1.069991913 0.065520887 0.14915498 1231.137062 1883170.156 0.025537045 0.029251583 5.28E-08 7.277695646 0.118159672 KPEDWDEEMDGEWEPPVIQNPEYK ddPTM_HeLa_Curcumin_4h_R1 2 KPEDWDEEMDGEWEPPVIQNPEYK 24 1 P27797;K7EJB9;K7EL50 P27797 CALR Calreticulin 0 0 ; ; 84.025 0.0001744 186271000 7302.5 5693.2 6665.7 6159.9 6670.5 8326.5 7247.4 5931.7 6234 5355.1 FALSE FALSE TRUE 6724.499419 6185.29484 6912.736706 6134.411966 6590.958644 6599.490041 7450.742539 7740.248024 5550.145797 5541.189326 1.213548035 1.116239579 1.247518592 1.107056916 1.189448376 1.190988009 1.344610714 1.396856806 1.001616344 1 12.43597995 -1 0.027060883 9.42E-13 2.889610955 0.717073733 0.065926232 700.9587134 1.471999024 52.71274828 116.2600384 0.1 1 2.889610955 MVIPNQPPLTATK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 MVIPNQPPLTATKK 14 1 C9JUT4;A0A087WZF1;Q93052;C9JXK9 C9JUT4 LPP Lipoma-preferred partner 0 1 MVIPNQPPLTATK(1)K 191.29 9.56E-57 0 350.42 343.49 280.33 250.18 353.38 547.73 551.06 1380.1 401.13 301.61 FALSE TRUE FALSE 322.6838872 373.179745 290.7192764 249.1448214 349.1661743 434.1246238 566.5212605 1800.886137 357.1270426 312.0909251 1.03394191 1.195740456 0.931521083 0.798308446 1.118796307 1.391019696 1.815244261 5.770389307 1.144304476 1 8.285822597 -4.108114228 1.887005416 1.024916202 8.780223497 0.987404208 0.158125501 0.093621924 0.24360033 0.021798928 1.448398422 7.80E-05 4.108114228 7.755307296 up KPEESLGK(ac)GAAQENGAPECSPR ddPTM_HeLa_Curcumin_4h_R1 2 KPEESLGKGAAQENGAPECSPR 22 2 Q6IE81;Q6IE81-2;Q6IE81-3 Q6IE81 JADE1 Protein Jade-1 0 1 ; KPEESLGK(1)GAAQENGAPECSPR;KPEESLGK(1)GAAQENGAPECSPR 227.2 5.62E-40 45484000 9888.7 7366.8 8100.5 8335.1 7885.4 9976.8 8116.8 6667.9 9211.4 8568.6 FALSE TRUE FALSE 9105.99896 8003.553366 8400.711656 8300.611565 7791.371755 7907.499218 8344.535563 8700.912015 8200.932466 8866.358212 1.027028092 0.902687797 0.947481644 0.936191767 0.878756708 0.891854246 0.941145774 0.981340005 0.924949373 1 13.11412594 -7.264364981 24.99773955 1.012763267 0.924377075 0.226687421 0.039857769 115.6110073 987832.2511 0.005113965 0.005984801 5.44E-08 7.264364981 -0.088386192 KPEK(ac)PLFSSASPQDSSPR ddPTM_HeLa_Curcumin_4h_R1 2 KPEKPLFSSASPQDSSPR 18 2 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 0 1 ; KPEK(1)PLFSSASPQDSSPR;KPEK(1)PLFSSASPQDSSPR 197.67 4.25E-13 8911000 3553.1 2589.8 2847.82 2462.79 2993.5 3993.3 3322.1 2032.88 2780 3007.3 FALSE TRUE FALSE 3271.868386 2813.650772 2953.362714 2452.599628 2957.804468 3165.044566 3415.309185 2652.695754 2475.040955 3111.803451 1.051437996 0.904186532 0.949083951 0.788160199 0.95051134 1.017109408 1.09753371 0.852462501 0.795371878 1 11.60353522 -7.26576438 24.83783914 1.024290165 0.941520828 0 0.108058782 433.196573 2487780.364 0.014021196 0.016323521 5.42E-08 7.26576438 -0.082769337 KPEKPLFSSAS(ph)PQDSSPR ddPTM_HeLa_Curcumin_4h_R1 2 KPEKPLFSSASPQDSSPR 18 2 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 0 KPEKPLFS(0.001)S(0.011)AS(0.417)PQDS(0.154)S(0.417)PR;KPEKPLFS(0.13)S(0.316)AS(0.454)PQDS(0.033)S(0.067)PR ; 77.668 0.002212 221260000 6972.2 5438.5 5997.1 5889.5 6496.1 7210 6015 4997.6 6333.7 6266.3 TRUE FALSE FALSE 6420.343013 5908.579707 6219.357802 5865.13081 6418.63825 5714.564727 6183.764711 6521.345234 5638.908956 6484.053459 0.990174287 0.91124784 0.959177441 0.904546955 0.989911371 0.881325973 0.953688114 1.005751306 0.869657999 1 12.66268027 -7.381492533 6.852246401 0.995671074 0.942592793 0 0.053587367 0.203794024 10.71218417 0.005689164 0.006483746 4.15E-08 7.381492533 -0.053078281 KPESPYGNLCDAPDS(ph)PRPVK ddPTM_HeLa_Curcumin_4h_R1 1 KPESPYGNLCDAPDSPRPVK 20 2 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 0 KPES(0.087)PY(0.23)GNLCDAPDS(0.682)PRPVK 76.586 0.0026955 10920000 1614.5 1338 1710.8 1643.1 1391.7 1364.7 1024.8 652.72 1822.7 1506.4 TRUE FALSE FALSE 1486.710621 1453.650758 1774.203753 1636.301288 1375.104886 1081.645837 1053.55313 851.7313232 1622.75437 1558.747288 0.953785539 0.932576287 1.138224115 1.049754056 0.882185905 0.693919948 0.67589733 0.546420404 1.041063156 1 10.60617133 -5.264297065 2.052923252 0.991605415 0.61381918 0.873223471 0.064711736 0.088783789 0.717471219 0.009785598 0.030248103 5.44E-06 5.264297065 -0.377786235 KPFEEHWR ddPTM_HeLa_Curcumin_4h_R1 2 KPFEEHWR 8 1 A0A087X1I3;P31040-3;P31040-2;P31040;D6RFM5 A0A087X1I3 SDHA "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial" 0 0 ; ; 56.916 0.018133 21207800 6788.5 5978.1 7017.6 6988.3 7779.9 9959 6615.5 5501.5 7922.2 5960.2 FALSE FALSE TRUE 6251.183062 6494.820326 7277.678429 6959.384266 7687.129774 7893.391139 6801.113125 7178.882024 7053.15448 6167.316506 1.013598549 1.053103132 1.180039718 1.128429887 1.246430237 1.279874501 1.102767001 1.164020367 1.143634265 1 12.59042717 -6.841864001 1.927738142 1.005437187 1.189261914 0.442815501 0.065482669 0.119272398 0.902857945 0.008453393 0.011776499 1.44E-07 6.841864001 0.183824727 KPGEK(ac)TFTQR ddPTM_HeLa_Curcumin_4h_R1 1 KPGEKTFTQR 10 2 Q15233;C9IZL7;C9JYS8;C9J4X2 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 1 KPGEK(1)TFTQR 84.821 0.007141 3720100 1793 1122.7 1622.1 1390.6 1552.2 1660.9 1575.3 3412.5 2058.7 1540.5 FALSE TRUE FALSE 1651.082158 1219.741185 1682.216453 1384.846066 1533.691029 1316.410618 1619.498678 4452.955541 1832.865761 1594.03226 1.035789676 0.765192284 1.05532146 0.868769159 0.962145539 0.825836873 1.015976099 2.793516575 1.149829778 1 10.63846511 -4.261742868 6.476271777 0.975412537 2.830166325 0.961932362 0.109175459 0.013550829 3.381695197 0.013213219 0.109869802 5.47E-05 4.261742868 1.854753789 KPGMFFNPEESELDLTYGNR ddPTM_HeLa_Curcumin_4h_R1 1 KPGMFFNPEESELDLTYGNR 20 1 P11413;P11413-3;P11413-2 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 0 138.97 0.00018132 24995000 1251.5 1053.8 1260.1 1025.7 1027.8 1834.7 1318.6 1319.9 1348 1256 FALSE FALSE TRUE 1152.442454 1144.885776 1306.800414 1021.455925 1015.544156 1454.162539 1355.596367 1722.331434 1200.127773 1299.645907 0.886735724 0.880921311 1.005504967 0.785949404 0.78140065 1.118891331 1.043050542 1.3252313 0.923426732 1 10.34390289 -4.230895356 1.266215271 0.926769503 1.505470833 0.656403942 0.091200887 0.783868112 1.000990685 0.014210354 0.5987496 5.88E-05 4.230895356 0.57870133 KPGPPLS(ph)PEIR ddPTM_HeLa_Curcumin_4h_R1 1 KPGPPLSPEIR 11 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 KPGPPLS(1)PEIR 74.853 0.015955 78629000 1460.7 1306.8 1258.4 1570.3 1630.8 1762.1 1775 1764.1 1882.4 1470.6 TRUE FALSE FALSE 1345.084054 1419.753969 1305.037411 1563.802515 1611.353775 1396.620597 1824.801723 2301.965969 1675.90543 1521.703241 0.883933226 0.933003184 0.85761624 1.02766589 1.058914598 0.917800896 1.1991837 1.512756172 1.101335257 1 10.57147132 -4.37372027 1.86752268 0.94773234 1.62322511 0.816510864 0.07873617 0.160806294 0.683027896 0.009832431 0.173792733 4.23E-05 4.37372027 0.67549277 KPGPSGPSES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 KPGPSGPSESPK 12 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 KPGPS(0.004)GPS(0.109)ES(0.887)PK;KPGPSGPS(0.007)ES(0.993)PK;KPGPS(0.001)GPS(0.048)ES(0.952)PK ;; 104.78 0.0033425 913767600 16882.3 14720.3 14535.2 16223.4 17434 18658 15489.5 12377.3 18005.8 14709.9 TRUE FALSE FALSE 15546.04814 15992.65714 15073.8873 16156.27187 17226.11094 14788.12048 15924.09368 16151.08179 16030.60879 15221.06793 1.021350684 1.050692186 0.990330466 1.061441414 1.131728143 0.97155604 1.046187676 1.061100434 1.053185549 1 13.89378196 -7.476577666 0.59534984 1.003009482 1.049210514 0 0.043308376 0.934736498 0.754529053 0.013876151 0.013927454 3.34E-08 7.476577666 0.046201032 KPIDSLRDS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 KPIDSLRDSR 10 2 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 KPIDS(0.002)LRDS(0.998)R;KPIDSLRDS(1)R ; 116.9 0.0036848 178222000 6466.4 6672.3 7062.2 6440.6 8582.9 8095.2 6685.8 4165.8 5392.5 5559.3 TRUE FALSE FALSE 5954.577617 7249.023881 7323.931345 6413.950504 8480.554523 6416.164268 6873.385554 5435.933243 4800.956241 5752.485261 1.035131312 1.260155142 1.273176899 1.114987734 1.474241852 1.11537257 1.194854961 0.94497126 0.834588186 1 12.48996967 -7.332633165 6.071924423 1.015768192 1.203905561 0.358999317 0.140444341 0.194816235 13.07702929 0.021021413 0.024002412 4.65E-08 7.332633165 0.188137368 KPISDNSFS(ph)SDEEQSTGPIK ddPTM_HeLa_Curcumin_4h_R1 1 KPISDNSFSSDEEQSTGPIK 20 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 0 KPIS(0.004)DNS(0.009)FS(0.493)S(0.493)DEEQS(0.001)TGPIK 67.217 0.0036006 17347000 3580.6 2694.3 3330.6 3077.7 3627.3 4076.2 3252.3 1874 3741.9 3516.8 TRUE FALSE FALSE 3297.191732 2927.183286 3454.034966 3064.965293 3584.046817 3230.750172 3343.550785 2445.373973 3331.422932 3639.008538 0.906068699 0.804390332 0.949169239 0.842252845 0.984896512 0.88781055 0.918808173 0.671989073 0.915475437 1 11.82932972 -13.52287577 0.020016583 2.128553933 8.26E-07 0.205166587 0.08144213 2270.593134 3.665280752 258.0654791 146.5372852 3.00E-14 13.52287577 -2.128553107 KPLAAPGDGEGLGQTAQPS(ph)PPAR ddPTM_HeLa_Curcumin_4h_R1 2 KPLAAPGDGEGLGQTAQPSPPAR 23 1 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 0 KPLAAPGDGEGLGQT(0.005)AQPS(0.995)PPAR;KPLAAPGDGEGLGQT(0.018)AQPS(0.982)PPAR ; 123.18 2.47E-06 22144200 5072 5028 4956.7 5242.4 5069 6540.2 4518.3 2861.1 5143.3 4584.5 TRUE FALSE FALSE 4670.545848 5462.597916 5140.399662 5220.708338 5008.555486 5183.688797 4645.071338 3733.436219 4579.092858 4743.811034 0.984555627 1.151520977 1.08360127 1.100530418 1.055808389 1.092726662 0.979185576 0.787012002 0.965277248 1 12.21183083 -4.295773362 3.469885062 1.028165371 0.765719724 0.627546878 0.059483509 0.158401909 3.279130814 0.0094393 0.103019966 5.06E-05 4.295773362 -0.262445647 KPLFHGDSEIDQLFR ddPTM_HeLa_Curcumin_4h_R1 2 KPLFHGDSEIDQLFR 15 1 A0A087WZZ9;P06493;A0A024QZP7;P06493-2 A0A087WZZ9 CDK1;CDC2 Cyclin-dependent kinase 1 0 0 ; ; 128.21 0.00021909 37352000 8223 6482.3 7481.8 7265.5 7605 14851.7 8985.3 7045.3 8908 8088.7 FALSE FALSE TRUE 7572.140873 7042.601127 7759.08209 7235.437286 7514.315342 11771.29001 9237.403335 9193.379537 7930.814687 8369.781723 0.904699922 0.841431875 0.927035178 0.864471443 0.897791076 1.406403464 1.103661199 1.098401349 0.947553347 1 13.03097428 -5.29064557 24.9987765 0.932879331 1.192905968 0.67939558 0.090718892 324.2145118 277508.0064 0.013336587 0.029825915 5.12E-06 5.29064557 0.260026637 KPLLESGTLGTK ddPTM_HeLa_Curcumin_4h_R1 1 KPLLESGTLGTK 12 1 P22314;P22314-2 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 0 124.42 2.97E-07 0 7090.3 5185.7 6967.6 5800.7 5998.1 7628.5 5996.9 5637.2 7108 6281.2 FALSE FALSE TRUE 6529.095273 5633.928801 7225.825385 5776.69824 5926.576575 6046.263109 6165.156874 7355.95633 6328.270183 6499.471232 1.004557916 0.866828793 1.111755884 0.888795109 0.91185519 0.930270001 0.948562837 1.131777658 0.973659234 1 12.66610664 TLLSESSSQSSKSPS(ph)LSSK ddPTM_HeLa_Curcumin_4h_R1 1 TLLSESSSQSSKSPSLSSK 19 1 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 0 T(0.006)LLS(0.139)ES(0.123)S(0.029)S(0.006)QS(0.095)S(0.095)KS(0.095)PS(0.376)LS(0.02)S(0.016)K 51.535 0.017263 285720000 2531.4 1997.1 2240.1 2189.9 2088 2213.3 1353 465.47 2167.9 2225.6 TRUE FALSE FALSE 2331.037019 2169.720425 2323.120077 2180.838774 2063.101964 1754.236631 1390.961539 607.3896602 1930.086794 2302.939434 1.012200748 0.942152621 1.008762993 0.946980516 0.895855937 0.761738066 0.603993973 0.26374539 0.838097071 1 11.16926075 -4.405550266 0.86801153 1.00058733 2.39E-17 0.931788731 0.058460218 0.136834169 0.087037114 0.004197002 0.123639052 3.93E-05 4.405550266 -1.00058733 down KPLVIIAEDVDGEALSTLVLNR ddPTM_HeLa_Curcumin_4h_R1 1 KPLVIIAEDVDGEALSTLVLNR 22 1 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 204.47 2.24E-17 1358300 617.77 589.84 535.44 756.21 773.21 1352.9 855.1 785.96 649.15 517.67 FALSE FALSE TRUE 568.8728526 640.8231413 555.2838774 753.0810034 763.9899757 1072.29329 879.0918046 1025.595586 577.9398691 535.658994 1.062005603 1.196326672 1.036636897 1.405896311 1.426261828 2.001820751 1.641140753 1.914642706 1.078932447 1 9.065171048 -5.767862466 1.119935265 1.03606847 1.856999467 0.873717506 0.12468987 0.104054093 0.255092709 0.018365827 0.052942271 1.71E-06 5.767862466 0.820930997 IRQEVGPPLPPLLAPLIAT(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 2 IRQEVGPPLPPLLAPLIATPPR 22 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 0 IRQEVGPPLPPLLAPLIAT(1)PPR;IRQEVGPPLPPLLAPLIAT(1)PPR ; 167.5 1.11E-08 191611000 4815 3510 3995.7 3738.5 3808.6 5229 2383.9 531.27 5024.4 3982.3 TRUE FALSE FALSE 4433.887669 3813.38876 4143.784157 3723.031078 3763.184932 4144.446457 2450.785818 693.2517773 4473.23589 4120.684629 1.076007525 0.925426016 1.00560575 0.903498184 0.913242646 1.005766476 0.594752096 0.168237038 1.085556478 1 12.00866834 -4.405414472 1.691406663 1.011149181 6.34E-11 0.939249957 0.065992516 0.118144654 0.405649976 0.009969766 0.175700619 3.93E-05 4.405414472 -1.011149181 down KPNEGADGQWK ddPTM_HeLa_Curcumin_4h_R1 2 KPNEGADGQWK 11 1 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 0 ; ; 123.26 0.00048121 10523800 10874.8 8928.8 8773.1 10216.2 11385.7 12177.1 9103.5 9044.9 10909.9 9485.9 FALSE FALSE TRUE 10014.0481 9700.565686 9098.238804 10173.92807 11249.93296 9651.432196 9358.919709 11802.64837 9713.111265 9815.534319 1.02022445 0.988287073 0.926922418 1.036512913 1.146135564 0.983281387 0.953480412 1.202445836 0.989565209 1 13.26085109 -6.006321412 24.98805337 1.001334586 1.060964989 0.226532591 0.071458427 438.2089008 1732219.739 0.010083791 0.017826821 9.86E-07 6.006321412 0.059630403 KPNEGADGQWK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 KPNEGADGQWKK 12 2 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 1 KPNEGADGQWK(1)K 76.868 0.012605 5323900 2429.9 2522.1 2021.3 1897.8 3143.3 4573 3252.9 3207.7 4970.1 2540 FALSE TRUE FALSE 2237.570851 2740.099086 2096.211156 1889.947406 3105.8182 3624.508252 3344.167619 4185.712964 4424.892465 2628.264811 0.851349088 1.042550611 0.79756467 0.719085611 1.181699115 1.379049872 1.272386103 1.592576572 1.683579389 1 11.35989493 -5.513157587 3.852876608 0.913375727 1.392665601 0.255774293 0.270355715 0.078440648 2.581283465 0.017656852 0.039180518 3.07E-06 5.513157587 0.479289874 Y(ph)ATPQVIQAPGPR ddPTM_HeLa_Curcumin_4h_R1 1 YATPQVIQAPGPR 13 0 A0A499FJ16;A0A5F9ZHD0;A0A5F9ZHP4;C9J1X3;A0A5F9ZI29;A0A5F9ZGX5;A0A5F9ZHJ2;Q07912;Q07912-3 A0A499FJ16 TNK2 Activated CDC42 kinase 1 1 0 Y(1)ATPQVIQAPGPR 124.42 0.013006 34678000 1432.4 1303.4 1359.9 1471.4 1269.7 1844.1 1001.1 416.21 1834 1351 TRUE FALSE FALSE 1319.024029 1416.060088 1410.29909 1465.311737 1254.559657 1461.612873 1029.188172 543.110513 1632.814788 1397.947149 0.943543559 1.012956812 1.008835771 1.048188222 0.897429962 1.045542296 0.736213935 0.388505755 1.168008954 1 10.4490941 -4.404676951 2.406919166 0.982180027 0.337044479 0.867332698 0.075855354 0.065535807 0.561435211 0.006547821 0.076064858 3.94E-05 4.404676951 -0.645135547 down KPPAPPS(ph)PVQSQSPSTNWSPAVPVK ddPTM_HeLa_Curcumin_4h_R1 1 KPPAPPSPVQSQSPSTNWSPAVPVK 25 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 KPPAPPS(0.872)PVQS(0.101)QS(0.025)PS(0.001)T(0.001)NWSPAVPVK 72.033 0.00029022 30159000 7052.2 6962.9 6433.2 6622.7 6776.6 7570.8 6366.6 11030 7090.9 5811.4 TRUE FALSE FALSE 6494.010929 7564.74205 6671.620051 6595.297022 6695.793471 6000.530739 6545.229661 14392.99622 6313.046011 6013.345717 1.079933074 1.257992207 1.109468899 1.096776625 1.113488861 0.99786891 1.088450585 2.393508855 1.049839192 1 12.55395219 -4.261564626 6.873195488 1.066050079 2.414645932 0.967492749 0.071687702 0.014622435 4.932471507 0.011152859 0.091258693 5.48E-05 4.261564626 1.348595853 KPPAPPS(ph)PVQSQSPSTNWSPAVPVKK ddPTM_HeLa_Curcumin_4h_R1 2 KPPAPPSPVQSQSPSTNWSPAVPVKK 26 2 A9Z1X7;Q8IYB3;Q8IYB3-2 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 KPPAPPS(0.82)PVQS(0.152)QS(0.024)PS(0.002)T(0.002)NWSPAVPVKK;KPPAPPS(0.927)PVQS(0.068)QS(0.005)PSTNWSPAVPVKK ; 80.844 2.91E-05 174979000 4318.5 3777.4 3995.9 4171.9 4156.4 4974.9 3700.5 7927.4 4417.1 3741.5 TRUE FALSE FALSE 3976.686168 4103.901624 4143.991569 4154.637783 4106.837645 3943.049661 3804.326071 10344.42777 3932.555181 3871.516847 1.027164888 1.06002422 1.07037932 1.073129202 1.060782584 1.01847669 0.982644845 2.671931488 1.015766 1 11.9186832 -4.260521059 24.99999687 1.026134496 2.671932004 0.996178736 0.03042486 3.593697425 97817.98544 0.004890102 0.039798019 5.49E-05 4.260521059 1.645797508 KPPLS(ph)PAQTNPVVQR ddPTM_HeLa_Curcumin_4h_R1 1 KPPLSPAQTNPVVQR 15 1 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 0 KPPLS(0.995)PAQT(0.005)NPVVQR 98.077 0.0021657 29039000 2490.1 1909 1922.8 2079.5 1801.2 1673.1 1454.2 1436.3 2269.5 2053.3 TRUE FALSE FALSE 2293.005957 2074.005454 1994.060659 2070.89558 1779.721866 1326.0802 1495.000938 1874.221258 2020.541528 2124.652022 1.079238357 0.976162417 0.938535176 0.974698708 0.837653342 0.624139947 0.703645078 0.882130927 0.950998802 1 11.05301086 -5.730304764 2.107853289 1.02540326 0.731561641 0.684053699 0.074642999 0.11285954 1.020924403 0.011306983 0.025127095 1.86E-06 5.730304764 -0.29384162 KPRAT(ph)T(ph)EVS(ph)SRK ddPTM_HeLa_Curcumin_4h_R1 1 KPRATTEVSSRK 12 3 Q15013;Q15013-3 Q15013 MAD2L1BP MAD2L1-binding protein 3 0 KPRAT(1)T(1)EVS(0.988)S(0.012)RK 60.628 0.0082731 0 434.35 450.76 498.91 483.67 556.22 638.43 491.92 702.84 675.37 617.89 TRUE FALSE FALSE 399.9707392 489.7216859 517.4000435 481.6687017 549.5874398 506.0124214 505.7219513 917.1326805 601.2836007 639.3616315 0.625578263 0.765954136 0.80924475 0.753358785 0.859587771 0.791433825 0.790979512 1.434450607 0.940443672 1 9.320488359 -4.260407801 24.53540495 0.809194399 1.434450867 0.7830776 0.097735405 31.44808782 747831.3748 0.018666717 0.152671798 5.49E-05 4.260407801 0.625256468 KPRPLS(ph)MDLTAR ddPTM_HeLa_Curcumin_4h_R1 1 KPRPLSMDLTAR 12 2 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 KPRPLS(0.998)MDLT(0.002)AR 77.633 0.019635 113300000 2964.5 3018.4 2710.7 2968.7 2735.4 4668.9 3328.9 858.28 3739.7 3006.9 TRUE FALSE FALSE 2729.856697 3279.297046 2811.160927 2956.416306 2702.782142 3700.517511 3422.299975 1119.965621 3329.464266 3111.389551 0.877375414 1.053965436 0.903506578 0.950191629 0.868673658 1.189345612 1.09992655 0.359956734 1.070089171 1 11.60334332 -4.253554807 24.77114811 0.965921147 0.359956398 0.766963479 0.104441627 322.6751596 1013729.168 0.014373765 0.208559932 5.58E-05 4.253554807 -0.605964748 KPS(ph)DLCT(ph)INVS(ph)GLK ddPTM_HeLa_Curcumin_4h_R1 1 KPSDLCTINVSGLK 14 1 E9PMT6 E9PMT6 XRRA1 3 0 KPS(1)DLCT(1)INVS(1)GLK 65.423 0.012675 9543700 2940.2 2378.4 2360.2 2857.1 2484.5 2896 2077.7 2169.5 3093.7 2561.6 TRUE FALSE FALSE 2707.480068 2583.978298 2447.671088 2845.278077 2454.87396 2295.336955 2135.99467 2830.970563 2754.32885 2650.615409 1.021453379 0.974859759 0.923435018 1.073440555 0.926152452 0.865963786 0.805848582 1.068042747 1.039128061 1 11.37211164 -5.580621019 8.723215933 1.004094452 0.90145471 0.264485775 0.072020749 0.242588434 33.71839143 0.009494322 0.019030541 2.63E-06 5.580621019 -0.102639741 QGSPDQVSPVS(ph)EMTSTSLYQDKQEGK ddPTM_HeLa_Curcumin_4h_R1 3 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 QGSPDQVS(0.138)PVS(0.824)EMT(0.036)S(0.002)TSLYQDKQEGK;QGS(0.009)PDQVS(0.169)PVS(0.765)EMT(0.055)S(0.002)TSLYQDKQEGK;QGSPDQVS(0.002)PVS(0.487)EMT(0.487)S(0.022)T(0.002)SLYQDKQEGK ;; 142.54 5.37E-08 59347000 4925.2 3506.2 3501.1 4273.1 4154.7 5902.8 4659.2 8343.9 5250.8 4487 TRUE FALSE FALSE 4535.365223 3809.260305 3630.853846 4255.419044 4105.157916 4678.492742 4789.924612 10887.9167 4674.800377 4642.922916 0.976834056 0.820444443 0.782018981 0.91653881 0.884175333 1.007661085 1.031661455 2.345056529 1.006865817 1 12.18081761 -4.258667609 4.468471625 0.952014464 2.442773983 0.966959711 0.07821335 0.028436612 1.408478352 0.012407218 0.133498875 5.51E-05 4.258667609 1.490759518 up KPS(ph)GDSQPSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 KPSGDSQPSSPR 12 1 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 2 0 KPS(0.962)GDS(0.038)QPS(0.002)S(0.998)PR 147.56 0.0010956 4367500 3688.9 2801.9 3189.5 3034.1 3267.6 3466.3 1897.9 1278.7 4017.2 2779.3 TRUE FALSE FALSE 3396.919672 3044.083751 3307.705676 3021.545698 3228.636004 2747.350307 1951.149966 1668.569744 3576.523211 2875.880468 1.181175543 1.058487578 1.150154088 1.050650655 1.122660013 0.955307544 0.678453082 0.5801944 1.243627213 1 11.489788 -4.795785993 2.250674358 1.08990841 0.583876775 0.884366932 0.069468239 0.075751802 0.733456046 0.009940067 0.04932378 1.60E-05 4.795785993 -0.506031636 KPS(ph)PEPEGEVGPPK ddPTM_HeLa_Curcumin_4h_R1 2 KPSPEPEGEVGPPK 14 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 0 KPS(1)PEPEGEVGPPK;KPS(1)PEPEGEVGPPK ; 99.092 0.0026729 79431000 8754.2 6668.6 7813.9 7554.7 8243.5 8537.7 7270 6655.5 7863.4 6875 TRUE FALSE FALSE 8061.295833 7245.004069 8103.490008 7523.440653 8145.201647 6766.88478 7473.976634 8684.731312 7000.804693 7113.905738 1.133174395 1.018428461 1.13910562 1.057568223 1.144969015 0.951219348 1.050615078 1.220810569 0.984101414 1 12.79642614 -9.531175337 1.267977526 0.999621153 1.089565281 0.222949978 0.071996912 0.62923133 1.799205626 0.049142931 0.011532835 2.94E-10 9.531175337 0.089944128 KPS(ph)PQPSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 KPSPQPSSPR 10 1 G3V5E1;O75909-1;O75909;O75909-4 G3V5E1 CCNK Cyclin-K 2 0 KPS(1)PQPS(0.123)S(0.877)PR;KPS(1)PQPS(0.007)S(0.993)PR;KPS(1)PQPS(0.064)S(0.936)PR ;; 140.33 0.0023191 162105000 19674.6 16524 16266.6 17530 16474 19241.6 16358.4 14721.6 19742.7 16606.2 TRUE FALSE FALSE 18117.33465 17952.26093 16869.45451 17457.4655 16277.55831 15250.67526 16817.37268 19210.14807 17576.9752 17183.26421 1.054359313 1.044752656 0.98173748 1.015957462 0.947291394 0.887530743 0.978706517 1.117956858 1.022912468 1 14.0687165 -6.74812587 24.24908546 1.027818139 0.982592145 0.114562695 0.056146789 268.5102571 489059.2932 0.00919933 0.012963537 1.79E-07 6.74812587 -0.045225994 KPS(ph)PS(ph)ESPEPWKPFPAVSPEPR ddPTM_HeLa_Curcumin_4h_R1 1 KPSPSESPEPWKPFPAVSPEPR 22 2 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 2 0 KPS(0.958)PS(0.565)ES(0.477)PEPWKPFPAVSPEPR 63.857 0.0024039 46446000 745.04 907.3 773.58 807.74 728.42 865.96 675.08 541.97 1025.1 932.64 TRUE FALSE FALSE 686.0692978 985.7229691 802.2495553 804.3977859 719.7340672 686.3501346 694.0209279 707.2141581 912.6490947 965.0491706 0.710916416 1.021422534 0.831304331 0.833530363 0.74580041 0.711207424 0.719156028 0.732827072 0.94570217 1 9.914458641 -13.52287875 0.274425956 2.616063732 0.758693416 0.425012475 0.088372298 33.6374472 0.452709805 29.82079349 0.047182078 3.00E-14 13.52287875 -1.857370316 ANSTSDS(ph)VFTETPSPVLK ddPTM_HeLa_Curcumin_4h_R1 1 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 0 ANSTS(0.007)DS(0.691)VFT(0.194)ET(0.092)PS(0.014)PVLK 87.429 0.0037726 51072000 2582.1 1483.7 2646.3 2464 2433.2 2770.2 3517.6 7090.9 1882.6 2576.2 TRUE FALSE FALSE 2377.72406 1611.944417 2744.374206 2453.804621 2404.185679 2195.629293 3616.294389 9252.882768 1676.08349 2665.722758 0.891962247 0.604693197 1.029504737 0.920502559 0.901888867 0.82365253 1.356590582 3.471059674 0.628753866 1 11.38031103 -4.258626678 2.860618477 0.917989435 3.935866294 0.965868296 0.146891646 0.042217825 0.476495674 0.016571948 0.295533205 5.51E-05 4.258626678 3.01787686 up KPS(ph)VSEEVQATPNK ddPTM_HeLa_Curcumin_4h_R1 3 KPSVSEEVQATPNK 14 1 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 0 KPS(0.964)VS(0.014)EEVQAT(0.023)PNK;KPS(0.598)VS(0.002)EEVQAT(0.4)PNK;KPS(0.725)VS(0.275)EEVQATPNK ;; 201.75 9.80E-09 110215000 13214.5 10395.3 10745.8 10190.2 10717 12394.7 13128.9 16742.9 12298.6 10868.2 TRUE FALSE FALSE 12168.55838 11293.82341 11144.0488 10148.03565 10589.20677 9823.899503 13497.2616 21847.73314 10949.47435 11245.86914 1.082046948 1.004264168 0.990945979 0.902378956 0.941608571 0.87355627 1.200197284 1.942734071 0.973644119 1 13.45710754 -4.287684131 3.102253151 1.008315657 2.05860933 0.950815439 0.065872293 0.057491182 0.856425134 0.010651687 0.14206609 5.16E-05 4.287684131 1.050293673 KPSDGS(ph)PDTKPSR ddPTM_HeLa_Curcumin_4h_R1 1 KPSDGSPDTKPSR 13 2 Q92733 Q92733 PRCC Proline-rich protein PRCC 1 0 KPS(0.187)DGS(0.673)PDT(0.132)KPS(0.008)R 81.01 0.015255 19749000 5019.3 4433.2 4177.4 4189.5 3915.3 5938.6 4670.9 1775.1 4296.2 4270 TRUE FALSE FALSE 4622.017109 4816.386054 4332.218119 4172.164959 3868.612605 4706.867418 4801.952883 2316.319818 3824.917609 4418.382182 1.04608812 1.090079096 0.98049873 0.944274349 0.875572199 1.065292051 1.086812477 0.524246143 0.865682834 1 12.1093025 -4.256334184 24.98926666 1.015214823 0.524245938 0.757855903 0.079070168 157.3120578 769996.7573 0.009044035 0.101844858 5.54E-05 4.256334184 -0.490968885 KPSGLNGEASKS(ph)QEMVHLVNK ddPTM_HeLa_Curcumin_4h_R1 2 KPSGLNGEASKSQEMVHLVNK 21 2 H0YE40;H0Y2P0;H0YD13;P16070-8;P16070-5;P16070-7;P16070-3;P16070-6;P16070-4;P16070-17;P16070-16;P16070-10;P16070-11;P16070-13;P16070-14;P16070-12;P16070-18;P16070 H0YE40 CD44 CD44 antigen 1 0 KPS(0.019)GLNGEAS(0.293)KS(0.689)QEMVHLVNK;KPS(0.037)GLNGEAS(0.28)KS(0.683)QEMVHLVNK ; 45.357 0.014308 160319000 4937 4458.5 5219.4 7594.5 5319 8856.8 3187 1361.55 10605.7 5249.4 TRUE FALSE FALSE 4546.231241 4843.872873 5412.835555 7563.075971 5255.574399 7019.799843 3276.418643 1776.680327 9442.281244 5431.816259 0.83696337 0.891759338 0.996505643 1.392365944 0.967553788 1.292348546 0.603190256 0.327087707 1.738328543 1 12.40721896 -4.559713897 6.312233251 0.980854549 0.39032651 0.390342814 0.295673421 0.080731182 8.91963356 0.025681139 0.101864545 2.76E-05 4.559713897 -0.590528038 KPSPQPSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 KPSPQPSSPR 10 1 G3V5E1;O75909-1;O75909;O75909-4 G3V5E1 CCNK Cyclin-K 1 0 KPSPQPS(0.004)S(0.996)PR 75.483 0.017521 126640000 4605.7 4169.3 4307.6 4328.1 4844 5729.6 4816.2 3618.9 4998.9 4314.9 TRUE FALSE FALSE 4241.153985 4529.675714 4467.243445 4310.191469 4786.238464 4541.216374 4951.32961 4722.285951 4450.533177 4464.842454 0.949900031 1.014520839 1.000537755 0.965362499 1.071983729 1.017105625 1.108959535 1.057660153 0.996795122 1 12.12439355 -5.545521938 1.068371019 0.978816652 1.079374109 0.549530555 0.030946553 0.276878657 0.588025951 0.005073224 0.018628522 2.85E-06 5.545521938 0.100557457 KPSPS(ph)ESPEPWKPFPAVSPEPR ddPTM_HeLa_Curcumin_4h_R1 1 KPSPSESPEPWKPFPAVSPEPR 22 2 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 KPS(0.019)PS(0.469)ES(0.469)PEPWKPFPAVS(0.043)PEPR 58.93 0.0079491 33903000 1321.3 1351.2 963.36 1337.5 1346.7 1847.3 1216.8 657.57 1334.3 1247.3 TRUE FALSE FALSE 1216.717711 1467.991707 999.0629691 1331.965779 1330.641482 1464.149157 1250.940133 858.0600659 1187.930628 1290.643582 0.942721699 1.137410612 0.774081228 1.032016738 1.030990663 1.134433376 0.96923748 0.664831157 0.920417259 1 10.33387493 -4.266159805 5.526913596 0.988985623 0.65402615 0.493261623 0.100006195 0.085145121 10.11642384 0.012668535 0.107200013 5.42E-05 4.266159805 -0.334959473 KPSPSES(ph)PEPWKPFPAVSPEPR ddPTM_HeLa_Curcumin_4h_R1 2 KPSPSESPEPWKPFPAVSPEPR 22 2 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 KPS(0.042)PS(0.122)ES(0.836)PEPWKPFPAVSPEPR;KPS(0.237)PS(0.221)ES(0.539)PEPWKPFPAVS(0.003)PEPR ; 63.936 0.0016148 145386000 5748.6 4456.8 5125.8 5717.5 5099.2 6209.1 4856.2 3061.2 5488.4 4752.1 TRUE FALSE FALSE 5293.592244 4842.025933 5315.766657 5693.8425 5038.39537 4921.262669 4992.451902 3994.545788 4886.336251 4917.235121 1.076538362 0.984704984 1.081047891 1.157935783 1.024639914 1.000819068 1.01529656 0.812356068 0.993716211 1 12.26363163 -3.626413823 1.348273258 1.04366925 0.069001551 0.643580912 0.05049348 3.060846836 1.418817019 0.007659934 6.227434259 0.000236367 3.626413823 -0.974667699 KPSVGVPPPAS(ph)PSYPR ddPTM_HeLa_Curcumin_4h_R1 2 KPSVGVPPPASPSYPR 16 1 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 1 0 KPSVGVPPPAS(0.655)PS(0.343)Y(0.001)PR;KPSVGVPPPAS(0.5)PS(0.5)YPR ; 93.73 0.0021262 380440000 10581.1 8386.7 8989.1 9847.2 9292.4 9639.9 6027.8 4242.9 10738.1 8501.2 TRUE FALSE FALSE 9743.59477 9111.608978 9322.243954 9806.454896 9181.594199 7640.476076 6196.923845 5536.540678 9560.157295 8796.616067 1.107652613 1.035808419 1.059753419 1.114798557 1.043764344 0.868569916 0.704466786 0.629394376 1.086799426 1 13.10273293 -4.926505722 1.887351871 1.056907427 0.636715068 0.956766563 0.034093146 0.067249417 0.450455685 0.006634794 0.031260717 1.18E-05 4.926505722 -0.420192359 KPVKENQSEGKGS(ph)DS(ph)DSEGDNPEK ddPTM_HeLa_Curcumin_4h_R1 1 KPVKENQSEGKGSDSDSEGDNPEK 24 3 I3L4J1;Q9UN37 I3L4J1 VPS4A Vacuolar protein sorting-associated protein 4A 2 0 KPVKENQS(0.095)EGKGS(0.776)DS(0.91)DS(0.22)EGDNPEK 49.125 0.013322 27882000 883.77 746.53 1209.3 1005.8 1327 1231.7 924.85 1075.9 989.55 905.12 TRUE FALSE FALSE 813.818672 811.0567267 1254.117722 1001.638266 1311.176392 976.2315359 950.7988019 1403.936957 880.9988407 936.5728526 0.868932587 0.865983596 1.339049833 1.069471812 1.399972664 1.042344472 1.015189368 1.499015216 0.940662372 1 9.871247411 -6.76954573 24.99984716 0.930968422 1.210095842 0.490444045 0.153294434 120.7153727 372283.7302 0.023611915 0.031332045 1.70E-07 6.76954573 0.27912742 GPS(ph)WDPFRDWYPHSR ddPTM_HeLa_Curcumin_4h_R1 1 GPSWDPFRDWYPHSR 15 1 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 0 GPS(1)WDPFRDWYPHSR 61.127 0.019396 231180000 1030.7 796.25 660.27 768.75 765.47 2301.6 1711.5 13299 958.79 746.57 TRUE FALSE FALSE 949.1190074 865.074302 684.740187 765.5691162 756.3422702 1824.222216 1759.520084 17353.80388 853.6131358 772.5132519 1.228611943 1.119818074 0.886379859 0.991010982 0.979067049 2.361412197 2.277656829 22.46408568 1.104981867 1 9.593415871 -4.258588115 4.585058294 1.174480786 23.85898717 0.995978868 0.403396686 0.009132866 0.49903556 0.06316755 0.66568367 5.51E-05 4.258588115 22.68450639 up TQT(ph)PPVS(ph)PAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_HeLa_Curcumin_4h_R1 1 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 3 0 T(0.45)QT(0.569)PPVS(0.962)PAPQPT(0.162)EERLPS(0.435)S(0.356)PVY(0.065)EDAAS(0.001)FK 56.741 0.00084846 21281000 3785.8 3096.8 3449.1 2698.2 2765.3 4487.3 4221.9 13102 4347.1 3303.4 TRUE FALSE FALSE 3486.149935 3364.473593 3576.92668 2687.035563 2732.325604 3556.583398 4340.355151 17096.73949 3870.234006 3418.192904 1.019880982 0.984284295 1.046437922 0.78609828 0.799347983 1.040486449 1.269780634 5.001689479 1.132245638 1 11.7390181 -4.258567365 4.176330397 0.984826343 5.337171345 0.99279497 0.102315563 0.012403998 0.47822446 0.014096826 0.161546177 5.51E-05 4.258567365 4.352345002 up T(ph)TSGDDACNLTSFR ddPTM_HeLa_Curcumin_4h_R1 1 TTSGDDACNLTSFR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0U1RQT6 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 T(0.74)T(0.13)S(0.13)GDDACNLTSFR 155.06 0.0011615 12281000 992.12 894.09 913.83 873 1033.5 925.51 1382.3 3623.9 1066 777.73 TRUE FALSE FALSE 913.5926551 971.3711556 947.6973437 869.3877573 1021.176188 733.5487934 1421.083618 4728.810428 949.062467 804.7560596 1.135241722 1.207038014 1.177620637 1.08031216 1.268926373 0.911516955 1.765856374 5.876079305 1.179316957 1 9.652407725 -4.258458059 3.173787495 1.093291538 6.600521507 0.994470341 0.105728668 0.017312155 0.267101759 0.015092172 0.236457487 5.51E-05 4.258458059 5.507229969 up KQAREES(ph)EESEAEPVQR ddPTM_HeLa_Curcumin_4h_R1 2 KQAREESEESEAEPVQR 17 2 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 0 KQAREES(0.945)EES(0.055)EAEPVQR;KQAREES(0.986)EES(0.014)EAEPVQR ; 73.346 0.011452 12269300 2197.33 1594.61 1448.05 2228.15 1121.72 2043.61 1285.53 1362.13 3504.8 1676.33 TRUE FALSE FALSE 2023.409012 1732.440983 1501.716007 2218.930506 1108.344222 1619.74225 1321.598512 1777.437167 3120.332209 1734.582343 1.166510786 0.99876549 0.865750775 1.279230424 0.638968929 0.933793807 0.76191166 1.024706134 1.798895407 1 10.76037261 -5.760124964 24.9999862 1.068603128 0.840989109 0.219505934 0.269710882 27.53203207 523635.1369 0.019744842 0.037822758 1.74E-06 5.760124964 -0.227614019 KQDDS(ph)PPRPIIGPALPPGFIK ddPTM_HeLa_Curcumin_4h_R1 1 KQDDSPPRPIIGPALPPGFIK 21 2 A0A0A0MRI1;Q8IXQ4-4;Q8IXQ4 A0A0A0MRI1 GPALPP1 GPALPP motifs-containing protein 1 1 0 KQDDS(1)PPRPIIGPALPPGFIK 57.922 0.010505 139360000 4024.5 3567.1 3604.6 3932.4 3645.7 4499.6 3682 4154.5 4574.6 3884.2 TRUE FALSE FALSE 3705.956578 3875.424229 3738.189647 3916.128771 3602.227409 3566.332239 3785.30701 5421.187925 4072.777825 4019.175661 0.922068825 0.964233603 0.930088646 0.974361188 0.896260256 0.887329278 0.941811787 1.348830801 1.013336606 1 11.97268392 -4.260678236 24.98015377 0.950529431 1.348830925 0.903878004 0.039231453 14.25695172 467813.6756 0.005791395 0.046451548 5.49E-05 4.260678236 0.398301494 KQDLS(ph)S(ph)S(ph)LT(ph)DDSK ddPTM_HeLa_Curcumin_4h_R1 1 KQDLSSSLTDDSK 13 1 A0A3B3IUB9;Q9NR09 A0A3B3IUB9 BIRC6 Baculoviral IAP repeat-containing protein 6 4 0 KQDLS(1)S(1)S(1)LT(1)DDSK 58.592 0.015077 15175000 981.93 698.62 893.6 642.37 1181.7 1011.4 894.36 546.4 522.81 725.39 TRUE FALSE FALSE 904.2092044 759.0055998 926.7176021 639.7120431 1167.608999 801.6242392 919.4533346 712.9948447 465.459051 750.5972485 1.20465297 1.011202214 1.234640287 0.852270701 1.555573247 1.067981851 1.224962304 0.949903355 0.620118248 1 9.551895191 KQEAESWS(ph)PDACLGVK ddPTM_HeLa_Curcumin_4h_R1 1 KQEAESWSPDACLGVK 16 1 E9PFK9;Q9UJ41;Q9UJ41-4;Q9UJ41-3;A0A0A0MSJ3;Q3HKR1 E9PFK9 RABGEF1 Rab5 GDP/GTP exchange factor 1 0 KQEAES(0.064)WS(0.936)PDACLGVK 67.214 0.013562 27570000 1230.9 963.01 958.22 1256.1 1135 1021.8 1003.1 710.89 1156.5 1121.4 TRUE FALSE FALSE 1133.472966 1046.248293 993.7324761 1250.902591 1121.465866 809.8671619 1031.244286 927.6370885 1029.634843 1160.368567 0.976821502 0.901651702 0.856393826 1.078021783 0.966473842 0.69793959 0.888721322 0.799433142 0.887334312 1 10.1803674 -4.576955119 0.376449505 0.994410672 0.675497118 0.216254269 0.09065833 3.724948543 0.428596629 0.026396348 0.515258312 2.65E-05 4.576955119 -0.318913554 KQEGPATQVDSAVGTLPAT(ph)SPQSTSVQAK ddPTM_HeLa_Curcumin_4h_R1 3 KQEGPATQVDSAVGTLPATSPQSTSVQAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06 E7ETY2 TCOF1 Treacle protein 1 0 KQEGPATQVDSAVGTLPAT(0.486)S(0.486)PQS(0.001)T(0.009)S(0.016)VQAK;KQEGPATQVDSAVGT(0.004)LPAT(0.498)S(0.498)PQSTSVQAK;KQEGPATQVDSAVGT(0.095)LPAT(0.427)S(0.427)PQS(0.017)T(0.025)S(0.01)VQAK ;; 187.72 1.33E-21 116421000 17206.8 13259.7 15393.1 15845.6 15080.4 17628.1 12576.3 8603 17454.9 14855.3 TRUE FALSE FALSE 15844.86362 14405.80938 15963.58183 15780.03511 14900.57608 13971.83335 12929.15713 11226.0151 15540.14114 15371.52057 1.030793509 0.937175299 1.038516766 1.026576065 0.969362531 0.908942826 0.841111136 0.730312596 1.010969674 1 13.90797226 -4.533477329 0.967076771 1.011899823 0.653185116 0.911007245 0.028109036 0.267889466 0.252185407 0.004432264 0.090120535 2.93E-05 4.533477329 -0.358714707 KQEGPATQVDSAVGTLPATS(ph)PQSTSVQAK ddPTM_HeLa_Curcumin_4h_R1 1 KQEGPATQVDSAVGTLPATSPQSTSVQAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06 E7ETY2 TCOF1 Treacle protein 1 0 KQEGPATQVDSAVGT(0.001)LPAT(0.488)S(0.501)PQS(0.002)T(0.006)S(0.002)VQAK 133.57 3.08E-12 75200000 4401.9 3340.5 3836.1 3886.4 3622.5 4586.9 3027.2 1926.1 4249.9 3507.3 TRUE FALSE FALSE 4053.48497 3629.237935 3978.269241 3870.319107 3579.304053 3635.525235 3112.135085 2513.359023 3783.696603 3629.178414 1.11691532 1.000016401 1.096190043 1.066444982 0.986257396 1.001748831 0.857531576 0.69254215 1.042576631 1 11.82542727 -4.215551871 1.009034891 1.055044643 0.469875991 0.895174797 0.038610535 0.547256713 0.4031663 0.007454761 0.352884478 6.09E-05 4.215551871 -0.585168652 KQELEEICHDLEAR ddPTM_HeLa_Curcumin_4h_R1 2 KQELEEICHDLEAR 14 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ; ; 130.47 0.00031208 6921800 4905.3 4130.3 4629.2 4795.2 3950.2 4656.9 4014.4 3974.4 5351.8 4886.4 FALSE FALSE TRUE 4517.040329 4487.304728 4800.762224 4775.358733 3903.096445 3691.006446 4127.03326 5186.176264 4764.72093 5056.202036 0.893366265 0.88748525 0.949479904 0.94445568 0.771942343 0.729995839 0.816231873 1.025705901 0.942351768 1 12.3038384 -5.779238483 24.37672353 0.942954612 0.826989694 0.278588629 0.078023788 165.1523613 226183.939 0.012310591 0.022352371 1.66E-06 5.779238483 -0.115964918 AAES(ph)AEIEPR ddPTM_HeLa_Curcumin_4h_R1 2 AAESAEIEPR 10 0 Q9NS91 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 0 AAES(1)AEIEPR;AAES(1)AEIEPR ; 118.77 0.0047802 42596000 3995.8 3813.5 3888 4227.1 4557.6 5187.6 2953.6 1259.63 4425.2 3835.8 TRUE FALSE FALSE 3679.528214 4143.121947 4032.0927 4209.60938 4503.253597 4111.633284 3036.470067 1643.685388 3939.766631 3969.093764 0.927044921 1.043845823 1.015872373 1.060597111 1.134579797 1.035912359 0.765028555 0.414121078 0.992611126 1 11.95459393 -4.404200258 2.509762487 0.996399387 0.371721355 0.910482356 0.059224992 0.099445912 0.945387625 0.010309306 0.114017219 3.94E-05 4.404200258 -0.624678032 down KQGGLGPMNIPLVSDPK ddPTM_HeLa_Curcumin_4h_R1 1 KQGGLGPMNIPLVSDPK 17 1 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 0 108.14 0.00069822 1976800 4520.3 3668 4617.8 4750 5111.4 5215.3 4480.9 4145.2 4433.4 3705.4 FALSE FALSE TRUE 4162.513485 3985.045576 4788.93973 4730.345759 5050.449893 4133.587991 4606.621994 5409.052398 3947.067112 3834.162374 1.08563829 1.039352324 1.249018498 1.233736419 1.31722379 1.078094141 1.201467634 1.410752042 1.029447041 1 11.90469572 -6.762474886 24.85335364 1.041488643 1.240972724 0.61221228 0.081649552 13.67994506 328337.2147 0.013168003 0.017869626 1.73E-07 6.762474886 0.199484082 KQGGLGPMNIPLVSDPK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 KQGGLGPMNIPLVSDPKR 18 2 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 1 KQGGLGPMNIPLVSDPK(1)R 127.2 3.12E-05 2646500 1257.7 1614.8 988.27 1177.5 2114.6 3226.6 2013.7 1856.1 3219.4 1328.7 FALSE TRUE FALSE 1158.151718 1754.376117 1024.896156 1172.627817 2089.384776 2557.366789 2070.199002 2422.016346 2866.239875 1374.872226 0.842370437 1.27602848 0.745448294 0.852899487 1.519693784 1.860075969 1.505739198 1.761630135 2.084731817 1 10.42508183 -5.670871778 4.487531653 0.93352356 1.68754184 0.222248758 0.396413319 0.058974083 2.126357538 0.022240556 0.045286244 2.13E-06 5.670871778 0.75401828 KQGGLGPMNIPLVSDPKR ddPTM_HeLa_Curcumin_4h_R1 2 KQGGLGPMNIPLVSDPKR 18 2 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 0 ; ; 93.716 0.0031784 10339400 4334.4 3375.6 3653.3 3426.8 3316.7 4249.1 2997.6 2988 4694.8 4155.9 FALSE FALSE TRUE 3991.327666 3667.371823 3788.694512 3412.62081 3277.150519 3367.788763 3081.704588 3899.027445 4179.792186 4300.317216 0.928147266 0.852814255 0.881026753 0.793574204 0.762071809 0.783148915 0.71662262 0.906683682 0.971972991 1 12.07022737 -7.144152722 0.668297726 0.985440903 0.780845801 0.694311965 0.049427016 0.225294937 0.212965124 0.012725448 0.016462885 7.18E-08 7.144152722 -0.204595101 KQGINEDQEESQK ddPTM_HeLa_Curcumin_4h_R1 2 KQGINEDQEESQK 13 1 D6R954;X6REK4;Q8TBZ6 D6R954 TRMT10A tRNA methyltransferase 10 homolog A 0 0 ; ; 36.284 0.018344 20360000 3721.4 2993.8 2377.6 1995.55 4970.8 8694.3 4061.8 3222.3 4996.8 2815.5 FALSE FALSE TRUE 3426.847263 3252.570732 2465.715948 1987.292943 4911.526457 6891.004175 4175.763176 4204.764436 4448.663541 2913.338415 1.176261311 1.116441095 0.846354112 0.682135976 1.685875706 2.365329115 1.433325821 1.44328047 1.526998552 1 11.50845758 -5.669019763 7.508166078 1.043676441 1.764089509 0.520130493 0.316887008 0.122369507 8.633287812 0.040932817 0.082056338 2.14E-06 5.669019763 0.720413068 KQIT(ph)MEELVR ddPTM_HeLa_Curcumin_4h_R1 3 KQITMEELVR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 KQIT(1)MEELVR;KQIT(1)MEELVR;KQIT(1)MEELVR ;; 86.344 0.012655 467951000 19952 16697.2 15844.9 13112.9 18314.3 44829.8 49671 16068.4 26400.6 17234.6 TRUE FALSE FALSE 18372.77815 18140.43157 16432.12593 13058.64229 18095.91393 35531.59414 51064.63458 20967.58119 23504.52023 17833.50107 1.030239552 1.017210894 0.921418956 0.732253428 1.014714602 1.9924071 2.863410521 1.175741158 1.317998084 1 14.12230234 -5.245992417 5.255028795 0.984587596 2.108521482 0.563844967 0.40327867 0.077564096 6.934592196 0.04870288 0.121860668 5.68E-06 5.245992417 1.123933886 KQITTS(ph)PITVR ddPTM_HeLa_Curcumin_4h_R1 1 KQITTSPITVR 11 1 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 0 KQIT(0.052)T(0.032)S(0.9)PIT(0.017)VR 69.456 0.019106 35755000 1540.1 1232.7 1505.6 1498.1 1069.1 1440 1283.2 896.91 1399.4 1796.5 TRUE FALSE FALSE 1418.19946 1339.249095 1561.39886 1491.901259 1056.351681 1141.327768 1319.203138 1170.37373 1245.889321 1858.928241 0.762912429 0.720441524 0.839945742 0.802559898 0.56825845 0.613970858 0.709657914 0.62959597 0.670219158 1 10.86025536 -13.52287875 0.109535635 2.041575572 0.509095505 0 0.122777967 36.71238617 0.295643052 8.506280887 0.445200841 3.00E-14 13.52287875 -1.532480067 KQLATK(ac)AAR ddPTM_HeLa_Curcumin_4h_R1 2 KQLATKAAR 9 2 K7EMV3;K7EP01;A0A590UJJ6;B4DEB1;K7EK07;K7ES00;P84243;Q6NXT2;Q5TEC6;Q71DI3;P68431 K7EMV3;Q5TEC6 H3F3B;H3F3A;H3F3C;HIST2H3PS2;HIST2H3A;HIST1H3A Histone H3;Histone H3.3;Histone H3.3C;Histone H3.2;Histone H3.1 0 1 ; KQLATK(1)AAR;KQLATK(1)AAR 156.83 1.04E-08 23285000 12080.6 2093.63 8450.5 6250.6 7058.9 19805.7 9057 2670.7 7130.5 7899.3 FALSE TRUE FALSE 11124.40776 2274.594048 8763.682964 6224.736673 6974.727228 15697.77456 9311.115044 3484.984136 6348.30199 8173.800087 1.360983587 0.278278649 1.072167519 0.761547457 0.853302889 1.92049896 1.139141519 0.426360334 0.7766647 1 12.99679124 -11.9365975 8.70031278 0.848666988 1.076195837 0 0.458377334 0 0 0 0.058205385 1.16E-12 11.9365975 0.227528848 KQMVIDVLHPGK ddPTM_HeLa_Curcumin_4h_R1 1 KQMVIDVLHPGK 12 1 E7ETK0;A0A2R8Y849;A0A2R8YD14;P62847-2;P62847-3;P62847;P62847-4 E7ETK0 RPS24 40S ribosomal protein S24 0 0 127.51 0.00070775 7439300 10705 9226.2 10045 9398 8968.2 13928 10480 9396.5 10494 9908.8 FALSE FALSE TRUE 9857.687954 10023.67162 10417.27654 9359.113566 8861.260072 11039.1758 10774.04059 12261.44959 9342.834455 10253.13006 0.96143206 0.977620644 1.016009401 0.912805505 0.86424926 1.076663978 1.050805025 1.195873798 0.911217784 1 13.32377678 -4.39647332 1.451224416 0.973275834 1.240784898 0.641621348 0.054497321 0.447133772 1.018347028 0.007501457 0.159620408 4.01E-05 4.39647332 0.267509064 KQPPVS(ph)PGTALVGSQK ddPTM_HeLa_Curcumin_4h_R1 2 KQPPVSPGTALVGSQK 16 1 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 0 KQPPVS(0.934)PGT(0.066)ALVGSQK;KQPPVS(0.715)PGT(0.285)ALVGSQK ; 120.41 0.00042807 662990000 9217 8899.6 9571.2 9111.7 10254.6 15340.5 14980.3 6283.8 8614.3 6764.8 TRUE FALSE FALSE 8487.464724 9668.841768 9925.917092 9073.9982 10132.32059 12158.70738 15400.6069 8199.701693 7669.332842 6999.876296 1.212516388 1.38128752 1.418013215 1.296308365 1.44749995 1.736988893 2.200125581 1.171406657 1.095638339 1 12.77311371 -6.441982301 0.389625279 1.015183795 1.800926776 0.420183165 0.253386158 0.861946378 0.271835625 0.105955451 0.267011841 3.61E-07 6.441982301 0.785742981 KQPPVSPGT(ph)ALVGSQKEPSEVPTPK ddPTM_HeLa_Curcumin_4h_R1 1 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 0 KQPPVS(0.064)PGT(0.936)ALVGSQKEPSEVPTPK 77.575 0.00010185 175310000 4749 3338.8 3451.9 3819.5 3662.4 5294.1 3359 2792.2 5000.8 4096.9 TRUE FALSE FALSE 4373.111639 3627.390995 3579.830451 3803.695921 3618.728272 4196.043983 3453.2445 3643.528926 4452.224751 4239.26697 1.031572597 0.855664675 0.844445626 0.897253216 0.853621227 0.989804137 0.814585287 0.859471449 1.050234577 1 12.04959911 -7.262047451 24.9837001 1.014909284 0.874778703 0.699914232 0.04590689 21.83954607 897312.5119 0.007317214 0.008638743 5.47E-08 7.262047451 -0.140130581 KQPPVSPGTALVGS(ph)QKEPSEVPTPK ddPTM_HeLa_Curcumin_4h_R1 1 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 0 KQPPVSPGT(0.002)ALVGS(0.571)QKEPS(0.335)EVPT(0.091)PK 68.705 0.000247 269140000 2471.1 2005.5 2203.7 1864.4 1922.1 3139.4 3655 2973 3099.4 2273.1 TRUE FALSE FALSE 2275.509828 2178.846484 2285.371061 1856.685607 1899.180213 2488.253052 3757.549463 3879.454014 2759.403574 2352.090056 0.967441626 0.926344839 0.971634166 0.789376921 0.807443664 1.057890214 1.597536393 1.649364574 1.173170886 1 11.19972758 -4.786219258 3.966508799 0.95295558 1.643170995 0.876051549 0.100346954 0.038954554 1.319600118 0.011577361 0.042342897 1.64E-05 4.786219258 0.690215415 KQPPVSPGTALVGSQKEPSEVPT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 KQPPVSPGTALVGSQKEPSEVPTPK 25 2 P17096;P17096-3 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 0 KQPPVSPGTALVGS(0.004)QKEPS(0.086)EVPT(0.91)PK;KQPPVSPGTALVGS(0.002)QKEPS(0.154)EVPT(0.844)PK ; 92.901 3.38E-05 176676000 5301.2 3872.9 4993 4932.5 4055.6 5951.3 4912 1846.96 6497.9 4996 TRUE FALSE FALSE 4881.604426 4207.656219 5178.044972 4912.090622 4007.239619 4716.933295 5049.8175 2410.089602 5785.096627 5169.610628 0.944288608 0.813921303 1.001631524 0.950185802 0.775153083 0.912434927 0.976827437 0.466203313 1.119058483 1 12.33583991 -4.25917184 24.9150549 0.945683067 0.466203138 0.707869167 0.092021122 69.61166174 764818.5826 0.010846258 0.096692668 5.51E-05 4.25917184 -0.479479928 KQQQEPTGEPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 KQQQEPTGEPSPK 13 1 F5H2U8;F5H2A4;F5H6H0;P52926-3;P52926-6;P52926-4;P52926-5;P52926-2;P52926 F5H2U8 HMGA2 High mobility group protein HMGI-C 1 0 KQQQEPT(0.008)GEPS(0.992)PK;KQQQEPT(0.017)GEPS(0.983)PK;KQQQEPT(0.022)GEPS(0.978)PK ;; 89.311 0.0058825 25748000 11568.46 10454.2 9976.39 11314.16 10608.42 12451.64 9815.68 7366.52 12983.32 10795.67 TRUE FALSE FALSE 10652.80418 11357.81446 10346.12379 11267.345 10481.92152 9869.029505 10091.08156 9612.538037 11559.08228 11170.81873 0.95362788 1.016739663 0.926174172 1.008640931 0.938330643 0.883465191 0.903343059 0.860504344 1.034756947 1 13.44744731 -5.437068321 3.18336637 0.97841709 0.884267751 0.681697319 0.032331912 0.105153072 2.040721885 0.003966365 0.009433621 3.66E-06 5.437068321 -0.094149338 NGIGPGSHSEFAAS(ph)IGSPK ddPTM_HeLa_Curcumin_4h_R1 1 NGIGPGSHSEFAASIGSPK 19 0 Q9H694;Q9H694-2;A6NGY7 Q9H694 BICC1 Protein bicaudal C homolog 1 1 0 NGIGPGS(0.002)HS(0.013)EFAAS(0.707)IGS(0.278)PK 54.943 0.014595 8239800 4158.8 2957.7 3159 3117.8 3515 4738.3 2710.9 1283.6 3701.2 3357.4 TRUE FALSE FALSE 3829.626592 3213.350409 3276.075319 3104.89937 3473.085921 3755.523168 2786.960558 1674.963731 3295.18762 3474.0694 1.102346024 0.924952855 0.943008024 0.893735563 0.999716909 1.081015586 0.802217871 0.482133066 0.94850944 1 11.76241086 -4.402726739 2.493088301 1.020187722 0.440134343 0.818926342 0.071145533 0.118876518 1.109535409 0.011277765 0.126354149 3.96E-05 4.402726739 -0.580053379 down AT(ph)SAGSS(ph)PSCSLAGR ddPTM_HeLa_Curcumin_4h_R1 2 ATSAGSSPSCSLAGR 15 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 2 0 AT(0.5)S(0.5)AGS(0.002)S(0.863)PS(0.129)CS(0.006)LAGR;AT(0.713)S(0.287)AGS(0.051)S(0.918)PS(0.026)CS(0.005)LAGR ; 126.07 0.0039022 19953000 11109.4 9394.5 9258.2 11759.5 10027.1 9682.3 6944.6 2855.22 10133.9 10182.9 TRUE FALSE FALSE 10230.07927 10206.51872 9601.317036 11710.8423 9907.533381 7674.081838 7139.446786 3725.763434 9022.236524 10536.75502 0.970894668 0.968658634 0.911221436 1.111427786 0.940283167 0.728315485 0.677575475 0.353596855 0.856263291 1 13.36314301 -4.402200528 0.972727779 0.988386546 0.131609019 0.868107897 0.074639809 0.3088072 0.25826996 0.009301126 0.261788986 3.96E-05 4.402200528 -0.856777528 down KQS(ph)LGELIGTLNAAK ddPTM_HeLa_Curcumin_4h_R1 2 KQSLGELIGTLNAAK 15 1 P60174;P60174-3 P60174 TPI1 Triosephosphate isomerase 1 0 KQS(1)LGELIGTLNAAK;KQS(1)LGELIGTLNAAK ; 101.61 0.0015973 772220000 15803.5 11963 13830.7 12890.2 13626.1 26965 24243 18044.8 15757 13844.4 TRUE FALSE FALSE 14552.6363 12997.02841 14343.27791 12836.86377 13463.61766 21372.15504 24923.19333 23546.57645 14028.49652 14325.49187 1.01585596 0.90726577 1.001241566 0.896085376 0.939836327 1.49189677 1.739779238 1.643683628 0.979268052 1 13.80629705 -5.138192104 3.465106231 0.986665884 1.681325737 0.97135784 0.052613496 0.029539723 0.649460914 0.008094227 0.022891001 7.27E-06 5.138192104 0.694659853 KQSATNLESEEDS(ph)EAPVDSTLNNNR ddPTM_HeLa_Curcumin_4h_R1 1 KQSATNLESEEDSEAPVDSTLNNNR 25 1 A0A3B3IRW6;Q2KHR3-2;Q2KHR3 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 0 KQSATNLES(0.016)EEDS(0.984)EAPVDSTLNNNR 87.05 6.10E-05 0 659.93 245.03 197.75 329.4 285.35 338.32 460.42 264.87 480.59 461.61 TRUE FALSE FALSE 607.6958441 266.2093014 205.078789 328.0370301 281.9473876 268.1486183 473.338146 345.6276437 427.8704794 477.6509131 1.272259358 0.557330247 0.42934868 0.686771492 0.590279176 0.561390361 0.990970881 0.723598834 0.895780721 1 8.899812812 -7.257663954 24.99171952 1.128566921 0.649147284 0.540442143 0.168248911 154.6226118 1023537.002 0.029287597 0.03514993 5.53E-08 7.257663954 -0.479419637 KQSEPFFK ddPTM_HeLa_Curcumin_4h_R1 2 KQSEPFFK 8 1 P11413;P11413-3;P11413-2;E9PD92;E7EM57;E7EUI8 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 0 ; ; 84.615 0.0098599 4813400 6054.4 4605.7 5211.5 5250 4872.8 5739.3 4868.9 5001.2 5297.9 5217.3 FALSE FALSE TRUE 5575.187851 5003.796185 5404.642775 5228.276891 4814.695043 4548.904485 5005.50823 6526.042857 4716.733625 5398.600787 1.032709784 0.926869088 1.001119177 0.968450363 0.891841281 0.842608051 0.927186215 1.208839682 0.873695576 1 12.39836982 -7.270946659 24.46503365 1.015446287 0.958921025 0 0.102480991 1032.945988 2658071.438 0.01540931 0.017745174 5.36E-08 7.270946659 -0.056525262 KQT(ph)Y(ph)VWTR ddPTM_HeLa_Curcumin_4h_R1 1 KQTYVWTR 8 1 O75473-3;O75473-2;O75473 O75473-3 LGR5 Leucine-rich repeat-containing G-protein coupled receptor 5 2 0 KQT(0.992)Y(0.999)VWT(0.009)R 60.972 0.0083534 0 1335.8 1154.7 1405.6 1171.1 1348.7 1674.6 1298 1075.3 1612.7 1388.2 TRUE FALSE FALSE 1230.07002 1254.507123 1457.692772 1166.254299 1332.617633 1327.269083 1334.418387 1403.15402 1435.790845 1436.439847 0.856332427 0.873344697 1.014795556 0.811906117 0.927722547 0.923999071 0.92897617 0.976827553 0.999548187 1 10.48828186 -9.557880161 1.349577757 0.999673314 0.906703569 0.268260226 0.05525702 0.44993377 1.476680746 0.037628978 0.009010614 2.77E-10 9.557880161 -0.092969745 KRAEFTVETR ddPTM_HeLa_Curcumin_4h_R1 2 KRAEFTVETR 10 2 P21333-2;P21333;F8WE98;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 103.31 0.0017253 9052700 10521.3 6228.8 10429.5 9547.1 10748.7 13608.9 9975.6 9988.6 9175.1 8777.4 FALSE FALSE TRUE 9688.528003 6767.189717 10816.02644 9507.59663 10620.52877 10786.26074 10255.48849 13034.07816 8168.614485 9082.413997 1.066734902 0.745087123 1.190875735 1.046813835 1.169350877 1.187598445 1.129158888 1.435089632 0.899388036 1 13.14886008 -1 0.437111733 1.015761068 8.929307929 0.54795274 0.118823077 41.78212606 0.462748037 0.023709138 295.3002332 0.1 1 7.913546861 KRAKLIS(ph)T(ph)VS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 KRAKLISTVSK 11 3 Q9Y3B9 Q9Y3B9 RRP15 RRP15-like protein 3 0 KRAKLIS(1)T(1)VS(1)K 70.1 0.0079896 0 1853.6 1472.8 1512.5 1307.3 1769.4 1821.8 1236.1 1393.3 1972.6 1794 TRUE FALSE FALSE 1706.885604 1600.102269 1568.554581 1301.890739 1748.301061 1443.938144 1270.781639 1818.110756 1756.210715 1856.341366 0.919489074 0.86196553 0.844970978 0.701320761 0.941799333 0.777840849 0.684562474 0.979405399 0.946060217 1 10.85824632 -7.50615687 0.796626107 0.982848883 0.810084795 0.314247324 0.088456526 0.382826721 0.511208694 0.022037978 0.022542338 3.12E-08 7.50615687 -0.172764088 KRAS(ph)T(ph)QAS(ph)SQK ddPTM_HeLa_Curcumin_4h_R1 1 KRASTQASSQK 11 2 P54296 P54296 MYOM2 Myomesin-2 3 0 KRAS(1)T(1)QAS(0.969)S(0.031)QK 71.176 0.0085565 0 1814 1482.4 2002.5 1960.4 2402.1 2958.3 2124.2 1814.6 2562.1 2400.6 TRUE FALSE FALSE 1670.419986 1610.532051 2076.714412 1952.288384 2373.456526 2344.715233 2183.799335 2367.863187 2281.04404 2484.020671 0.672466218 0.648356944 0.83602944 0.785938864 0.955489845 0.943919372 0.879138954 0.953238117 0.91828706 1 11.27846146 -5.758473372 24.99662099 0.820828208 0.929886952 0.264122724 0.099388021 131.3454986 1106919.853 0.02039577 0.039413454 1.74E-06 5.758473372 0.109058744 KRCS(ph)EELVK ddPTM_HeLa_Curcumin_4h_R1 1 KRCSEELVK 9 2 Q96JM4-2;Q96JM4 Q96JM4-2 LRRIQ1 Leucine-rich repeat and IQ domain-containing protein 1 1 0 KRCS(1)EELVK 51.762 0.020132 38581000 7495.2 6101.1 8101.6 8984.9 6050.4 4107.7 5996.6 5423.7 5406.8 6449.2 TRUE FALSE FALSE 6901.947011 6628.451898 8401.852423 8947.722864 5978.252932 3255.716717 6164.848457 7077.361162 4813.687567 6673.30922 1.034261531 0.993278099 1.259023394 1.340822457 0.895845335 0.487871401 0.923806803 1.060547463 0.72133441 1 12.70418664 -5.533973626 24.98235798 1.057700981 0.810350009 0.214975184 0.20526172 206.3188969 464567.7244 0.02628718 0.052611101 2.92E-06 5.533973626 -0.247350972 KRDFTNEAPPAPLPDASASPLS(ph)PHRR ddPTM_HeLa_Curcumin_4h_R1 2 KRDFTNEAPPAPLPDASASPLSPHRR 26 3 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 KRDFTNEAPPAPLPDAS(0.006)AS(0.078)PLS(0.916)PHRR;KRDFTNEAPPAPLPDAS(0.002)AS(0.05)PLS(0.948)PHRR ; 69.439 0.00018226 123560000 7672.2 5559 5980.3 6807.7 5473.5 9613 5087.1 3700.3 9761.4 7377.4 TRUE FALSE FALSE 7064.937274 6039.49519 6201.935179 6779.531541 5408.232087 7619.155439 5229.830335 4828.504436 8690.598842 7633.764101 0.925485407 0.791155596 0.812434743 0.888098119 0.70846204 0.99808631 0.68509195 0.632519472 1.138442153 1 12.89817889 -1.824018429 0.125386741 1.079690095 2.03E-13 0.562495284 0.101081745 39.38494651 0.41091322 0.366098546 7.307285932 0.014996212 1.824018429 -1.079690095 KRDHANYEEDENGDIT(ph)PIK ddPTM_HeLa_Curcumin_4h_R1 1 KRDHANYEEDENGDITPIK 19 2 H3BSB3;H3BNT4;Q99547 H3BSB3 MPHOSPH6 M-phase phosphoprotein 6 1 0 KRDHANY(0.001)EEDENGDIT(0.999)PIK 59.728 0.010038 19795000 4931.8 4360.6 4532.2 4743.9 4268.6 6730.9 5849.5 3429.9 5633.4 4236.9 TRUE FALSE FALSE 4541.442826 4737.510834 4700.167319 4724.270999 4217.699733 5334.835467 6013.621227 4475.660721 5015.430114 4384.13196 1.035881873 1.080604069 1.072086188 1.077584124 0.962037587 1.216851025 1.371678882 1.020877282 1.143996157 1 12.09807551 -5.247782655 23.93582073 1.027943924 1.219990094 0.321415554 0.094077988 259.2548847 454387.7251 0.011151272 0.028246685 5.65E-06 5.247782655 0.192046169 KRDS(ph)DAGS(ph)STPTTSTR ddPTM_HeLa_Curcumin_4h_R1 1 KRDSDAGSSTPTTSTR 16 2 P51532;P51532-4;P51532-3;P51532-2;P51532-5;A0A0A0MT49;Q9HBD4;A0A2R8Y4P4;A0A2R8Y7S2;A0A2R8YGG3;A0A2R8Y440;A0A2R8Y4C5;A0A2R8Y6N0;A0A2R8YG32;A0A2R8Y7F3;A0A2R8YF80;A0A2R8YF58;A0A2R8Y526;A0A2R8Y7Y7;A0A2R8Y6V2;A0A2R8YDA1;A0A2R8Y523;A0A2R8Y5K3;K7EQF0;A0A2R8YFK5;K7EP28 P51532 SMARCA4 Transcription activator BRG1 2 0 KRDS(1)DAGS(0.384)S(0.311)T(0.097)PT(0.097)T(0.08)S(0.026)T(0.006)R 70.501 0.018022 11283000 2766.4 2376.1 2536.9 2747.4 3020.3 4351.3 3773.8 1095.5 3459.1 2625.2 TRUE FALSE FALSE 2547.436521 2581.479496 2630.919746 2736.031987 2984.284895 3448.791331 3879.682671 1429.512907 3079.645384 2716.425505 0.937789944 0.950322213 0.968522693 1.007217751 1.098607302 1.269606446 1.428230837 0.526247786 1.133712439 1 11.40749377 -5.821869079 3.365679265 0.968633335 1.120690324 0.010644972 0.223575275 0.430500893 9.881716862 0.029808109 0.058216812 1.51E-06 5.821869079 0.152056989 KREDS(ph)APPSSVAR ddPTM_HeLa_Curcumin_4h_R1 1 KREDSAPPSSVAR 13 2 Q9BZE4-3;Q9BZE4-2;Q9BZE4 Q9BZE4-3 GTPBP4 Nucleolar GTP-binding protein 1 1 0 KREDS(1)APPSSVAR 92.427 0.003175 5127600 3429.1 3358.7 3238.9 3488.6 3596.6 4898.5 2650.7 1981.4 4051.6 3518.3 TRUE FALSE FALSE 3157.683117 3649.011062 3358.936483 3474.165098 3553.712894 3882.495883 2725.071508 2585.519739 3607.149617 3640.560663 0.867361763 1.002321181 0.922642635 0.954293973 0.976144397 1.066455484 0.748530724 0.71019823 0.990822555 1 11.82994493 -4.659472785 7.106043772 0.950431698 0.72151198 0.758819916 0.053801001 0.092615135 5.605651278 0.008697582 0.033015695 2.19E-05 4.659472785 -0.228919718 KREEGS(ph)DIEDEDMEELLNDTR ddPTM_HeLa_Curcumin_4h_R1 9 KREEGSDIEDEDMEELLNDTR 21 2 F5H5U2;Q8NHQ9-2;Q8NHQ9 F5H5U2 DDX55 ATP-dependent RNA helicase DDX55 1 0 KREEGS(1)DIEDEDMEELLNDTR;KREEGS(1)DIEDEDMEELLNDTR;KREEGS(1)DIEDEDMEELLNDTR;KREEGS(1)DIEDEDMEELLNDTR;KREEGS(1)DIEDEDMEELLNDTR;KREEGS(1)DIEDEDMEELLNDTR;KREEGS(1)DIEDEDMEELLNDTR;KREEGS(1)DIEDEDMEELLNDTR;KREEGS(1)DIEDEDMEELLNDTR ;;;;;;;; 124.25 3.98E-06 207907600 27177.3 21872.5 25104 25011.4 24651.3 29111.7 23645.1 22464.9 28489.2 23833.8 TRUE FALSE FALSE 25026.18803 23763.06144 26034.37632 24907.90945 24357.34935 23073.60526 24308.51787 29314.34459 25364.00604 24662.02278 1.014766236 0.963548759 1.055646431 1.009970256 0.987646049 0.93559257 0.985666021 1.188643156 1.02846414 1 14.59000351 -4.258678007 24.92408561 1.000540108 1.188643227 0.76420239 0.031752322 88.80515669 801506.0105 0.004241344 0.039680794 5.51E-05 4.258678007 0.188103119 KREESYLSNSQT(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 KREESYLSNSQTPER 15 2 Q5VY60;Q7Z4H7-3;Q7Z4H7 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 0 KREESYLSNSQT(1)PER 90.872 0.014915 4801000 1668.2 1713.7 1875.9 1794.9 2021.9 2187.8 1797.7 1189.7 2022.2 1983.4 TRUE FALSE FALSE 1536.16021 1861.824592 1945.422504 1787.473179 1997.790163 1734.025618 1848.138624 1552.434053 1800.369719 2052.323002 0.748498267 0.907179128 0.94791244 0.870951199 0.973428725 0.844908729 0.900510603 0.756427741 0.877235073 1 11.00304209 -9.673613119 1.545091624 0.999703757 0.856073111 0.009566132 0.078810574 0.383667595 1.65461013 0.055552902 0.012525897 2.12E-10 9.673613119 -0.143630646 KREPEDEGEDDD ddPTM_HeLa_Curcumin_4h_R1 1 KREPEDEGEDDD 12 2 P39687 P39687 ANP32A Acidic leucine-rich nuclear phosphoprotein 32 family member A 0 0 90.827 0.013884 3358900 2940.1 2688 2665 2614.6 2557 3175.8 2218.4 2307.2 2622.4 2740.9 FALSE FALSE TRUE 2707.387983 2920.338743 2763.767244 2603.781478 2526.509445 2517.103281 2280.642333 3010.654659 2334.729281 2836.146071 0.954601038 1.029685591 0.974479866 0.918070301 0.890824866 0.887508336 0.804134299 1.061530183 0.823204878 1 11.46971612 -6.22108177 3.618129158 0.982654118 0.902183756 0.017445079 0.080074114 0.231093109 6.353041643 0.008903667 0.01488561 6.01E-07 6.22108177 -0.080470363 KRFT(ph)PEEEMFK ddPTM_HeLa_Curcumin_4h_R1 1 KRFTPEEEMFK 11 2 A0A5F9ZI30;A0A5F9ZGY4;A0A5F9ZHS1;A0A5F9ZGX3;A0A5F9ZHE4;D6RHE1;A0A5F9ZHR8;A0A5F9ZHD2;A0A5F9ZGY3;I6L894;A0A5F9ZI40;A0A5F9ZHN5;A0A5F9ZH19;A0A5F9ZHT8;A0A5F9ZI46;A0A5F9ZI65;A0A5F9ZGZ5;A0A5F9ZHT4;A0A5F9ZHF7;A0A5F9ZH30;Q01484 A0A5F9ZI30 ANK2 Ankyrin-2 1 0 KRFT(1)PEEEMFK 76.357 0.015111 9985700 4302.1 3535.3 3950.3 3708.3 4483.8 4303 4000.1 4060.5 4168.2 3630.1 TRUE FALSE FALSE 3961.584245 3840.875579 4096.701593 3692.956037 4430.333613 3410.509295 4112.33204 5298.527758 3710.958888 3756.245705 1.054665897 1.022530442 1.090637279 0.983150818 1.179457885 0.907956924 1.094798467 1.410591365 0.987943596 1 11.87507572 -4.285225442 3.807808259 1.031542437 1.440240226 0.734153094 0.068566759 0.07770168 2.160925048 0.008269177 0.084982688 5.19E-05 4.285225442 0.408697789 KRKPS(ph)PEPEGEVGPPK ddPTM_HeLa_Curcumin_4h_R1 1 KRKPSPEPEGEVGPPK 16 3 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 0 KRKPS(1)PEPEGEVGPPK 73.296 0.0099231 126740000 8493 5738.4 5800.6 7177.5 5554.1 7202 5769.8 5207.6 8334.5 7554.3 TRUE FALSE FALSE 7820.770088 6234.401726 6015.575339 7147.801407 5487.870985 5708.224017 5931.685059 6795.373267 7420.226202 7816.811363 1.000506437 0.797563282 0.769568953 0.914413957 0.702060051 0.730249683 0.75883692 0.869328036 0.949265098 1 12.93236451 -7.254153189 6.212609293 1.000483115 0.788044812 0.671916526 0.060962695 0.055165522 10.09456396 0.009690077 0.011543097 5.57E-08 7.254153189 -0.212438304 KRNEDEDS(ph)PNKLYTLVTYVPVTTFK ddPTM_HeLa_Curcumin_4h_R1 1 KRNEDEDSPNKLYTLVTYVPVTTFK 25 3 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2 H7C2W9 RPL31 60S ribosomal protein L31 1 0 KRNEDEDS(0.856)PNKLY(0.125)T(0.013)LVT(0.003)Y(0.003)VPVTTFK 87.319 3.01E-05 34069000 3930.6 2691.8 3615.3 2910.9 3021.1 7217 4333.2 4806.8 4052.9 3144.3 TRUE FALSE FALSE 3619.488862 2924.467198 3749.286198 2898.855467 2985.075356 5720.112848 4454.77793 6272.371192 3608.30701 3253.564191 1.112468865 0.898850315 1.152362756 0.890978415 0.91747855 1.758106652 1.369199336 1.927846148 1.109032064 1 11.6678053 -5.261015777 24.99983554 1.029723864 1.653465599 0.794434989 0.156550104 11.90399152 702509.2459 0.02011579 0.048032605 5.48E-06 5.261015777 0.623741735 KRNEDEDSPNKLYTLVT(ph)YVPVTTFK ddPTM_HeLa_Curcumin_4h_R1 1 KRNEDEDSPNKLYTLVTYVPVTTFK 25 3 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2 H7C2W9 RPL31 60S ribosomal protein L31 1 0 KRNEDEDS(0.125)PNKLY(0.192)T(0.208)LVT(0.246)Y(0.226)VPVT(0.003)T(0.001)FK 43.888 0.013353 40056000 5288.9 3950.7 4684.1 4592 4547.6 9699.2 6238.3 6566.1 6237.8 4883.7 TRUE FALSE FALSE 4870.277984 4292.180904 4857.696867 4572.999521 4493.37284 7687.476587 6413.329908 8568.073663 5553.528946 5053.408211 0.963761046 0.849363583 0.961271416 0.904933726 0.889176701 1.521245913 1.269109805 1.695503966 1.098967017 1 12.30304101 -5.25998858 24.99976426 0.959182762 1.472668912 0.820895985 0.116011464 34.63323424 596781.4965 0.014104537 0.033935079 5.50E-06 5.25998858 0.51348615 KRPSLPS(ph)SPSPGLPK ddPTM_HeLa_Curcumin_4h_R1 1 KRPSLPSSPSPGLPK 15 2 O43294;H3BQC4;O43294-2;H3BSN4 O43294 TGFB1I1 Transforming growth factor beta-1-induced transcript 1 protein 1 0 KRPS(0.03)LPS(0.463)S(0.463)PS(0.044)PGLPK 72.772 0.018371 89747000 1880 1508.7 1906.3 1674.3 2020.2 2443.2 2153.9 2403.7 2125.4 1934.1 TRUE FALSE FALSE 1731.196016 1639.105305 1976.949155 1667.37219 1996.110434 1936.452779 2214.332637 3136.577065 1892.248937 2001.309831 0.865031486 0.819016266 0.987827634 0.833140458 0.997402003 0.967592698 1.106441693 1.567262108 0.945505243 1 10.96672882 -3.993345491 1.363826932 0.925220185 2.231184909 0.90763125 0.061936695 0.559052596 0.565457024 0.01029631 1.194159543 0.000101544 3.993345491 1.305964725 LKS(ph)EDGVEGDLGETQSR ddPTM_HeLa_Curcumin_4h_R1 4 LKSEDGVEGDLGETQSR 17 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 LKS(1)EDGVEGDLGETQSR;LKS(0.609)EDGVEGDLGET(0.39)QS(0.001)R;LKS(0.999)EDGVEGDLGET(0.001)QSR;LKS(0.978)EDGVEGDLGET(0.021)QS(0.001)R ;;; 133.9 0.0033256 36547700 5534.86 4641.2 5910.38 5531.52 5485.94 7173.5 7962.7 18713.2 6858.3 7424.5 TRUE FALSE FALSE 5096.769991 5042.364647 6129.423882 5508.632036 5420.523748 5685.635238 8186.111931 24418.76854 6105.961649 7682.500822 0.663425896 0.656344173 0.797842268 0.717036309 0.705567611 0.740076099 1.065553017 3.178492147 0.794788284 1 12.9073603 -4.258437338 3.517952459 0.799058598 3.472454194 0.981251903 0.099574891 0.03936609 0.841807051 0.020204882 0.27925244 5.52E-05 4.258437338 2.673395596 up KRS(ph)VQEGENPDDGVR ddPTM_HeLa_Curcumin_4h_R1 2 KRSVQEGENPDDGVR 15 2 H7C5M1;Q5TCT4;A2A2V2;P42696-2;P42696 H7C5M1 RBM34 RNA-binding protein 34 1 0 KRS(1)VQEGENPDDGVR;KRS(1)VQEGENPDDGVR ; 82.651 0.0039717 21050200 2773.5 3565.9 3060.3 4310.4 2362.5 2801.6 1747.98 1941.01 3748.3 4407.1 TRUE FALSE FALSE 2553.974548 3874.120507 3173.71741 4292.564707 2334.32873 2220.516579 1797.023614 2532.815014 3337.120868 4560.246397 0.560051876 0.849541926 0.695953055 0.941301047 0.511886536 0.486929079 0.394062833 0.555411878 0.73178521 1 12.15489606 -13.52287875 0.132500037 2.288193283 0.434031933 0.308872759 0.161851842 54.20967937 0.507015057 18.77110887 0.564203669 3.00E-14 13.52287875 -1.85416135 KS(ph)ASPEVSEGHENQHGQESEAK ddPTM_HeLa_Curcumin_4h_R1 1 KSASPEVSEGHENQHGQESEAK 22 1 O60930 O60930 RNASEH1 Ribonuclease H1 1 0 KS(0.719)AS(0.199)PEVS(0.081)EGHENQHGQES(0.001)EAK 43.164 0.014182 5620600 2783.7 2318.6 2167.7 2048.5 3146.8 5573.1 3208.2 2331.8 3360.6 2827.1 TRUE FALSE FALSE 2563.367208 2519.009453 2248.036869 2040.02385 3109.276465 4417.176238 3298.213458 3042.755086 2991.950588 2925.341515 0.876262547 0.861099273 0.768469889 0.697362629 1.062876403 1.509969423 1.127462705 1.040136706 1.022769674 1 11.51438934 -5.522358414 24.99932994 0.902866577 1.227751264 0.542373913 0.145417463 11.47133886 551133.678 0.021537493 0.04347576 3.00E-06 5.522358414 0.324884687 KS(ph)FTPDHVVYAR ddPTM_HeLa_Curcumin_4h_R1 1 KSFTPDHVVYAR 12 1 Q6NZI2;Q6NZI2-3;Q6NZI2-2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 0 KS(1)FTPDHVVYAR 123.95 0.0014819 97777000 2917.1 2266.2 2367 2331.1 2329.9 4373.4 3845.5 1685 4194.2 2534.7 TRUE FALSE FALSE 2686.208457 2462.08023 2454.723102 2321.454526 2302.117464 3466.307542 3953.39438 2198.748743 3734.106753 2622.780636 1.024183426 0.938728995 0.935923908 0.885111966 0.877739233 1.3216155 1.507329407 0.838327351 1.423720574 1 11.35688143 -5.256951787 24.97280802 0.982838054 1.250914626 0.154338781 0.214964998 295.5986137 1644954.424 0.021480565 0.052782201 5.53E-06 5.256951787 0.268076572 KS(ph)KIS(ph)T(ph)MY(ph)Y(ph)LNQDAK ddPTM_HeLa_Curcumin_4h_R1 1 KSKISTMYYLNQDAK 15 2 B7Z739;Q8TCQ1-2 B7Z739 1-Mar 5 0 KS(1)KIS(1)T(1)MY(1)Y(1)LNQDAK 44.457 0.018577 9217700 1376.8 1412.2 1233.1 1610.7 1527.3 1354.6 1551.9 1375.6 1229.1 1507.5 TRUE FALSE FALSE 1267.824827 1534.264275 1278.799771 1604.03535 1509.087945 1073.640691 1595.442137 1795.014108 1094.270805 1559.885513 0.812767871 0.983574924 0.819803608 1.028303255 0.967435067 0.688281724 1.022794381 1.15073452 0.701507127 1 10.60722443 -6.246263986 24.81611259 0.909625727 0.958397655 0.08366805 0.139093602 2624.654447 4292060.562 0.01986337 0.032856071 5.67E-07 6.246263986 0.048771927 KS(ph)KSPPKVPIVIQDDSLPAGPPPQIR ddPTM_HeLa_Curcumin_4h_R1 1 KSKSPPKVPIVIQDDSLPAGPPPQIR 26 3 Q7Z422-4;Q7Z422-5;Q7Z422 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 0 KS(0.5)KS(0.5)PPKVPIVIQDDSLPAGPPPQIR 59.943 0.0020329 93504000 2160 1434 1706.8 1627.9 1566.9 1673.4 1705.6 1775.2 1931.2 1828.1 TRUE FALSE FALSE 1989.033721 1557.94857 1770.055509 1621.164181 1548.215741 1326.317977 1753.454546 2316.450308 1719.352192 1891.626339 1.051493987 0.823602705 0.935732112 0.857021362 0.818457488 0.701152204 0.926956085 1.224581335 0.908928025 1 10.88541142 -7.271496781 24.66024465 1.024316608 0.888531889 0.061691596 0.1328564 698.0697372 1711628.7 0.021763344 0.025046508 5.35E-08 7.271496781 -0.135784719 KS(ph)LPEEDVAEIQHAEEFLIKPESK ddPTM_HeLa_Curcumin_4h_R1 2 KSLPEEDVAEIQHAEEFLIKPESK 24 2 O60832;H7C2Q9;H7C0M1;C9IYT0;O60832-2 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 0 KS(1)LPEEDVAEIQHAEEFLIKPESK;KS(1)LPEEDVAEIQHAEEFLIKPESK ; 71.289 0.00026615 41484000 4352.3 4296.6 4309.6 4690.3 4799.1 6783.5 4868.3 2369.3 5643.7 4340.1 TRUE FALSE FALSE 4007.810862 4667.978959 4469.317567 4670.892781 4741.873867 5376.525634 5004.891396 3091.688663 5024.60023 4490.918152 0.892425719 1.039426416 0.995190163 1.040075241 1.055880714 1.197199649 1.114447252 0.688431309 1.11883585 1 12.13279471 -7.236120724 23.18779355 0.949201031 1.03056714 0 0.137295427 610.2984557 558934.3238 0.020767666 0.0254274 5.81E-08 7.236120724 0.08136611 KS(ph)LSDSESDDS(ph)K ddPTM_HeLa_Curcumin_4h_R1 2 KSLSDSESDDSK 12 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 2 0 KS(0.981)LS(0.004)DS(0.001)ES(0.015)DDS(1)K;KS(0.995)LS(0.004)DS(0.006)ES(0.003)DDS(0.992)K ; 128.74 0.0023397 15025000 8119.2 7591.2 9267.9 8070 8755.4 8875.2 7169.8 6050.4 8144.6 8049.3 TRUE FALSE FALSE 7476.556753 8247.349502 9611.376527 8036.608478 8650.997573 7034.383476 7370.965291 7895.139107 7251.157757 8329.012576 0.897652235 0.990195348 1.153963503 0.964893306 1.038658244 0.844563916 0.884974686 0.947908175 0.870590324 1 13.02392976 -5.254563761 24.99333015 0.975190838 0.891731504 0.232894895 0.077015718 719.5176363 2615487.315 0.011186221 0.027836433 5.56E-06 5.254563761 -0.083459334 KPDAEVLTVES(ph)PEEEAMTK ddPTM_HeLa_Curcumin_4h_R1 1 KPDAEVLTVESPEEEAMTK 19 1 Q8IVF2;Q8IVF2-3;Q8IVF2-2 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 KPDAEVLTVES(0.999)PEEEAMT(0.001)K 126.3 9.25E-05 49723000 2460.3 1853.6 2104.2 2272.8 2349.2 4436.7 5748.3 44450 0 1669.6 TRUE FALSE FALSE 2265.564659 2013.816925 2182.183503 2263.395756 2321.187324 3516.478408 5909.581827 58002.60038 0 1727.618476 1.311380198 1.165660678 1.263116558 1.310124769 1.343576349 2.035448484 3.420652135 33.57373239 0 1 10.75456894 -4.258366124 4.245284988 1.265819093 36.16976419 0.997509888 0.48296325 0.00625645 0.255959668 0.058522916 0.661586762 5.52E-05 4.258366124 34.90394509 up KS(ph)SPEMEDAR ddPTM_HeLa_Curcumin_4h_R1 1 KSSPEMEDAR 10 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 0 KS(0.5)S(0.5)PEMEDAR 131.79 0.0041994 18697000 2188.5 1538.3 2017.4 2319.4 1861.1 2418.2 1926.3 1118.9 2393 2224.7 TRUE FALSE FALSE 2015.277916 1671.263797 2092.166619 2309.802937 1838.907598 1916.638061 1980.346794 1460.047459 2130.493887 2302.008159 0.875443429 0.726002552 0.908844137 1.003386077 0.798827576 0.832593948 0.860269233 0.634249472 0.92549363 1 11.16867723 -7.621586627 0.031579983 1.789037385 4.85E-18 0.326132121 0.090060532 80.20561803 2.039180764 58.50453086 56.42152034 2.39E-08 7.621586627 -1.789037385 KS(ph)SPPASSPQPEAPTSSWR ddPTM_HeLa_Curcumin_4h_R1 1 KSSPPASSPQPEAPTSSWR 19 1 P43250-2 P43250-2 1 0 KS(0.565)S(0.435)PPAS(0.001)SPQPEAPTSSWR 68.567 0.0052604 6002100 649.67 602.03 553.24 688.26 736.33 726.93 402.06 498.7 638.81 552.16 TRUE FALSE FALSE 598.247934 654.0667906 573.7435611 685.4121625 727.5497457 576.1565238 413.3407215 650.7513343 568.7341412 571.3475189 1.047082405 1.144779261 1.004193669 1.199641444 1.273392675 1.008416952 0.723448878 1.13897639 0.99542594 1 9.158224713 -4.990293153 24.98241796 1.061924606 0.914892695 0.17460552 0.130086004 264.1698887 679879.086 0.017652017 0.052865597 1.02E-05 4.990293153 -0.147031911 KS(ph)SPSVKPAVDPAAAK ddPTM_HeLa_Curcumin_4h_R1 2 KSSPSVKPAVDPAAAK 16 2 H3BV90;Q6FI81-3;Q6FI81;H3BPG7;H3BT65 H3BV90 CIAPIN1 Anamorsin 1 0 KS(0.744)S(0.254)PS(0.002)VKPAVDPAAAK;KS(0.499)S(0.499)PS(0.003)VKPAVDPAAAK ; 87.496 0.0054038 625520000 11660.1 8155.1 9607.5 9643.9 9976.7 11761.8 8792 4358.6 10545.1 9445.4 TRUE FALSE FALSE 10737.19078 8859.990506 9963.562402 9603.996097 9857.734368 9322.270097 9038.679858 5687.517075 9388.328913 9773.626947 1.098588154 0.906520226 1.019433467 0.982644022 1.008605549 0.953818899 0.924803034 0.58192492 0.960577784 1 13.25467832 -3.888096101 1.203355012 1.027569337 2.59E-16 0.824911542 0.054818729 0.938337627 0.617192359 0.008685299 1.492272429 0.000129391 3.888096101 -1.027569337 KS(ph)STPLSEAK ddPTM_HeLa_Curcumin_4h_R1 1 KSSTPLSEAK 10 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 KS(0.583)S(0.241)T(0.173)PLS(0.004)EAK 110.93 0.01135 5849600 2298.9 2244.7 2313.2 2390.1 2396 4269.5 3857.6 1751.3 2906.8 1977.5 TRUE FALSE FALSE 2116.939639 2438.721866 2398.929227 2380.210399 2367.429265 3383.957573 3965.833874 2285.263308 2587.931312 2046.217978 1.034562135 1.191819196 1.172372276 1.163224263 1.15697804 1.653762018 1.938128741 1.116823004 1.264738821 1 10.99874412 -5.352895232 3.819171567 1.056752767 1.60714502 0.433761385 0.210871846 0.114318621 3.072599293 0.027398564 0.065312327 4.44E-06 5.352895232 0.550392253 KS(ph)STSGSDFDTK ddPTM_HeLa_Curcumin_4h_R1 1 KSSTSGSDFDTK 12 1 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6;A0A096LNW1 P46100-5 ATRX Transcriptional regulator ATRX 1 0 KS(0.314)S(0.314)T(0.314)S(0.052)GS(0.006)DFDTK 66.826 0.019342 33303000 2440.6 2142.4 2047 2708.1 2409.1 2885.7 2065.4 1917 3325.2 2251.3 TRUE FALSE FALSE 2247.423935 2327.57951 2122.863621 2696.8946 2380.373056 2287.173291 2123.349565 2501.484475 2960.433879 2329.532507 0.964753197 0.999161635 0.911283107 1.157697775 1.021824357 0.981816431 0.911491709 1.073813938 1.27082746 1 11.18582475 KS(ph)SVNGSSATSSG ddPTM_HeLa_Curcumin_4h_R1 1 KSSVNGSSATSSG 13 1 R4GMX3;P35226 R4GMX3 COMMD3-BMI1;BMI1 Polycomb complex protein BMI-1 1 0 KS(0.469)S(0.469)VNGS(0.051)S(0.007)ATS(0.002)S(0.001)G 91.307 0.018115 8065900 3414.6 6586.7 3258.2 2928.6 2786 2744.8 2158.5 2935.7 2375.6 2951 TRUE FALSE FALSE 3144.330807 7156.024998 3378.951758 2916.482229 2752.77877 2175.49754 2219.061701 3830.781416 2115.002623 3053.54703 1.029730597 2.343512291 1.106566142 0.955112923 0.901502005 0.712449331 0.726716071 1.254534932 0.692637972 1 11.57627035 -6.159390654 3.903296066 1.141057852 0.88042311 0.105258276 0.432784917 0.533586787 14.65030056 0.066166879 0.112390171 6.93E-07 6.159390654 -0.260634742 KS(ph)T(ph)DEPS(ph)EK ddPTM_HeLa_Curcumin_4h_R1 1 KSTDEPSEK 9 1 Q5VZC3;A0A3B3IUC7;P09467 Q5VZC3 FBP1 "Fructose-1,6-bisphosphatase 1" 3 0 KS(1)T(1)DEPS(1)EK 98.156 0.019048 12833000 7093.8 5348 5081.2 6726.3 6003 157.73 2110.7 1342.7 6053.7 5538.2 TRUE FALSE FALSE 6532.318245 5810.25729 5269.513742 6698.468353 5931.418146 125.01502 2169.920561 1752.083049 5389.624256 5730.652038 1.139890924 1.013891133 0.919531269 1.168884153 1.035033729 0.021815148 0.3786516 0.305738865 0.940490579 1 12.48448358 -5.272601427 25 1.058314712 0.249726852 0.910802945 0.11386063 125.7631247 281675.7642 0.015308922 0.034527608 5.34E-06 5.272601427 -0.80858786 IAS(ph)DEEIQGTKDAVIQDLER ddPTM_HeLa_Curcumin_4h_R1 5 IASDEEIQGTKDAVIQDLER 20 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;Q8WX93-4;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 0 IAS(0.985)DEEIQGT(0.015)KDAVIQDLER;IAS(0.999)DEEIQGT(0.001)KDAVIQDLER;IAS(0.998)DEEIQGT(0.002)KDAVIQDLER;IAS(0.943)DEEIQGT(0.057)KDAVIQDLER;IAS(1)DEEIQGTKDAVIQDLER ;;;; 107.21 0.00013349 344755100 4791.09 3294.61 3343.43 4334.49 2938.41 6000.83 5398.83 12419.29 6204.57 5549.08 TRUE FALSE FALSE 4411.870171 3579.381408 3467.340457 4316.555029 2903.37138 4756.190215 5550.30664 16205.87435 5523.944194 5741.910117 0.768362806 0.623378168 0.603865332 0.751762905 0.505645564 0.828328922 0.966630708 2.822383844 0.962039475 1 12.48731503 -4.258300519 4.032154105 0.809895816 3.005971925 0.941440558 0.153215201 0.047251341 1.605746074 0.025442239 0.30272037 5.52E-05 4.258300519 2.19607611 up KS(ph)Y(ph)T(ph)T(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 KSYTTPK 7 1 P62979;J3QTR3 P62979 RPS27A Ubiquitin-40S ribosomal protein S27a;Ubiquitin;40S ribosomal protein S27a 4 0 KS(1)Y(1)T(1)T(1)PK 57.174 0.0073221 0 820.3 658.95 621.27 797.45 670.2 836.92 787.71 1220.7 707.5 872.99 TRUE FALSE FALSE 755.3723894 715.9067018 644.2948127 794.1503632 662.2083027 663.333358 809.8110226 1592.885811 629.8890201 903.3263375 0.836212073 0.792522782 0.713247014 0.879140052 0.733077599 0.734323057 0.896476709 1.763355882 0.697299518 1 9.819103463 -4.262308474 6.055465009 0.868350906 1.786385467 0.873867067 0.106694587 0.03664928 6.615090151 0.016304057 0.138074391 5.47E-05 4.262308474 0.918034561 KS(ph)YESSEDCSEAAGSPAR ddPTM_HeLa_Curcumin_4h_R1 1 KSYESSEDCSEAAGSPAR 18 1 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 0 KS(0.707)Y(0.128)ES(0.147)S(0.017)EDCSEAAGSPAR 70.335 0.0065799 24494000 2790.5 2569.4 2817.7 2355.5 2316.2 2671 1878 1755.6 3262.9 3530.1 TRUE FALSE FALSE 2569.62898 2791.487487 2922.126441 2345.753565 2288.580828 2117.004492 1930.691626 2290.874358 2904.968033 3652.770712 0.703473933 0.76421098 0.799975326 0.642184728 0.626532845 0.579561286 0.528555384 0.627160733 0.795277958 1 11.83477548 -13.52287875 0.105102421 2.199695896 0.406970567 0.623080251 0.080213377 27.23496309 0.211956745 7.069487294 0.412980341 3.00E-14 13.52287875 -1.792725329 KSAEPSANTTLVS(ph)ET(ph)EEEGSVPAFGAAAK ddPTM_HeLa_Curcumin_4h_R1 1 KSAEPSANTTLVSETEEEGSVPAFGAAAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 2 0 KS(0.005)AEPS(0.004)ANT(0.348)T(0.348)LVS(0.636)ET(0.636)EEEGS(0.023)VPAFGAAAK 63.138 0.0009494 7487900 1510.8 1837.3 1815.5 1613.3 1934.4 2318.2 2152.8 714.71 1559.5 1896.1 TRUE FALSE FALSE 1391.218586 1996.108025 1882.784027 1606.624592 1911.333543 1837.379189 2213.201774 932.6217889 1388.426752 1961.989334 0.709085703 1.017389845 0.959630103 0.818875294 0.974181414 0.936487858 1.128039656 0.475344984 0.707662742 1 10.93810148 -5.967877652 0.007393624 1.742450305 3.79E-05 0 0.184573461 32411.49634 79.16329083 9105.272587 9550.520828 1.08E-06 5.967877652 -1.742412393 KSAEPSANTTLVS(ph)ETEEEGSVPAFGAAAK ddPTM_HeLa_Curcumin_4h_R1 1 KSAEPSANTTLVSETEEEGSVPAFGAAAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 KSAEPSANTT(0.008)LVS(0.735)ET(0.25)EEEGS(0.007)VPAFGAAAK 99.969 1.81E-08 285730000 3753.1 3630.6 3912.6 3784.8 4711.2 4112.8 3795 3494 3562.9 2865.7 TRUE FALSE FALSE 3456.038175 3944.412886 4057.604398 3769.1395 4655.022017 3259.758919 3901.477486 4559.304516 3172.058784 2965.282862 1.165500337 1.33019785 1.368370097 1.271089362 1.569840799 1.099307915 1.315718489 1.537561416 1.069732276 1 11.53395402 -7.695428669 0.728641458 1.02581255 1.364733116 0.509561415 0.12719391 0.313115444 0.363909472 0.038047596 0.033739732 2.02E-08 7.695428669 0.338920566 KSAEPSANTTLVSET(ph)EEEGSVPAFGAAAK ddPTM_HeLa_Curcumin_4h_R1 1 KSAEPSANTTLVSETEEEGSVPAFGAAAK 29 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 KSAEPSANTTLVS(0.129)ET(0.85)EEEGS(0.021)VPAFGAAAK 134.03 3.57E-12 269420000 5593.6 5016.9 5041.6 5404.3 6263.5 6006 5459.4 5465.7 5642.2 4310.8 TRUE FALSE FALSE 5150.860658 5450.538481 5228.446131 5381.938439 6188.811853 4760.287898 5612.576071 7132.166769 5023.264776 4460.599979 1.154746151 1.22192945 1.172139657 1.206550344 1.387439332 1.067185563 1.258255862 1.598925437 1.126141057 1 12.12302206 -1 0.116474145 0.910436644 2.447606094 0.466297932 0.117882319 55.19449418 0.445144084 0.546429148 13.77347079 0.1 1 1.53716945 KSCGSMLGLWGQR ddPTM_HeLa_Curcumin_4h_R1 1 KSCGSMLGLWGQR 13 1 A0A140T9Y1;A0A140T8X7 A0A140T9Y1 0 0 87.001 0.015088 53346000 2223.7 1751.4 1966.6 2282 2298.9 2709.1 2232.5 2012.9 2383.7 2287.1 FALSE FALSE TRUE 2047.691799 1902.783212 2039.483926 2272.557689 2271.487119 2147.202122 2295.137942 2626.623944 2122.214074 2366.576555 0.865254832 0.80402352 0.861786584 0.960272206 0.959819835 0.907303048 0.969813521 1.109883362 0.896744316 1 11.20858588 -4.276759741 2.424091295 0.922079289 1.14965847 0.540339814 0.055438542 0.420190266 3.059476404 0.009916395 0.195750252 5.29E-05 4.276759741 0.227579182 APYS(ph)PTTSK ddPTM_HeLa_Curcumin_4h_R1 2 APYSPTTSK 9 0 Q96JH7 Q96JH7 VCPIP1 Deubiquitinating protein VCIP135 1 0 APY(0.002)S(0.472)PT(0.472)T(0.044)S(0.011)K;APYS(0.945)PT(0.049)T(0.004)S(0.001)K ; 124.67 0.0050262 82840000 9890.1 8861 11205.3 10112.8 11282.9 9955.1 7083.2 3119.9 9696.6 8750.8 TRUE FALSE FALSE 9107.288149 9626.905356 11620.57828 10070.95591 11148.35879 7890.300043 7281.935529 4071.143148 8632.90724 9054.889649 1.005786763 1.063172024 1.283348415 1.112211888 1.231197642 0.871385555 0.804199257 0.449607152 0.953397289 1 13.14448134 -4.401681139 1.545813549 1.04861266 0.329737089 0.7557381 0.111090923 0.339551413 0.917258451 0.017262878 0.339118461 3.97E-05 4.401681139 -0.718875571 down KSDGIYIINLK ddPTM_HeLa_Curcumin_4h_R1 1 KSDGIYIINLK 11 1 C9J9K3;A0A0C4DG17;P08865;F8WD59 C9J9K3 RPSA 40S ribosomal protein SA 0 0 113.77 1.38E-05 0 488.05 455.01 424.96 469.31 423.84 1468.3 876.22 611.67 450.25 575.13 FALSE FALSE TRUE 449.4203275 494.3390369 440.7093914 467.3681196 418.7859848 1163.758029 900.804375 798.1653672 400.8587015 595.1157247 0.755181402 0.830660351 0.740544021 0.785339893 0.703705124 1.955515508 1.513662533 1.341193543 0.673581095 1 9.217026428 -5.271802815 24.99819276 0.848664562 1.594477736 0.821280866 0.173310601 215.9528551 520911.3652 0.025137178 0.056787017 5.35E-06 5.271802815 0.745813174 KSDIDEIVLVGGSTR ddPTM_HeLa_Curcumin_4h_R1 3 KSDIDEIVLVGGSTR 15 1 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 0 ;; ;; 122.31 0.0001002 5668600 9098.3 7957.1 8158.1 8342.3 8263.03 10002.2 6688.8 5174.43 9676.4 6706.66 FALSE FALSE TRUE 8378.159955 8644.876268 8460.446363 8307.781773 8164.498764 7927.630972 6876.469726 6752.089887 8614.923129 6939.715936 1.207277075 1.245710393 1.219134391 1.197135711 1.176488899 1.142356697 0.99088634 0.97296344 1.241394202 1 12.76066089 -4.744429139 7.120558721 1.134198052 0.980391653 0.432836122 0.077747457 0.158035188 35.02635212 0.014174968 0.050638468 1.80E-05 4.744429139 -0.1538064 KSDVEAIFSK ddPTM_HeLa_Curcumin_4h_R1 1 KSDVEAIFSK 10 1 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;G3V576;G3V555;G3V575;B7ZW38;A0A0G2JPF8;P0DMR1;B4DSU6;G3V251;G3V3K6;G3V5X6;G3V4M8;G3V2H6;A0A0G2JNQ3;O60812;B2RXH8 P07910;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL1;HNRNPCL2 Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoprotein C-like 1;Heterogeneous nuclear ribonucleoprotein C-like 2 0 0 109.72 0.0015612 7696300 15444 12428 13975 12840 14155 17679 14730 12822 13740 12783 FALSE FALSE TRUE 14221.5911 13502.22094 14492.92579 12786.87148 13986.21087 14012.17612 15143.28416 16731.36877 12232.75638 13227.2083 1.075177073 1.020791435 1.095690449 0.966709769 1.057381917 1.059344935 1.144858674 1.264920639 0.924817701 1 13.69122098 -4.37192136 1.481902562 1.035589862 1.327152511 0.708672729 0.049117055 0.311075786 0.722289421 0.005489108 0.12451293 4.25E-05 4.37192136 0.29156265 KSEAPAEVTHFS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 KSEAPAEVTHFSPK 14 1 Q6PID6 Q6PID6 TTC33 Tetratricopeptide repeat protein 33 1 0 KSEAPAEVTHFS(1)PK 101.05 0.0022703 38778000 4463.2 3745.9 3907 4476.5 4404.6 5418 3853.5 3615.9 5145.6 4733.8 TRUE FALSE FALSE 4109.93301 4069.678905 4051.796857 4457.977429 4352.078022 4294.245727 3961.618839 4718.371264 4581.140554 4898.299198 0.839053076 0.8308351 0.827184436 0.910107213 0.888487584 0.876680977 0.808774368 0.963267264 0.935251272 1 12.25806518 -9.28675204 0.981958877 1.001075855 0.864719233 0.388808671 0.047359649 0.308275031 0.526335737 0.029696724 0.007760899 5.17E-10 9.28675204 -0.136356622 KSEEEIDFLR ddPTM_HeLa_Curcumin_4h_R1 2 KSEEEIDFLR 10 1 B0QY90;B0QY89;Q9Y262-2;Q9Y262 B0QY90 EIF3L Eukaryotic translation initiation factor 3 subunit L 0 0 ; ; 128.35 0.0046207 31992000 12847.9 10154.9 10148.7 11593.4 11378.9 13903.9 10357.4 9915.1 12582.9 11886.3 FALSE FALSE TRUE 11830.97516 11032.64431 10524.81975 11545.42958 11243.21405 11020.07441 10648.00077 12938.16835 11202.58735 12299.34804 0.961918885 0.897010498 0.85572176 0.938702567 0.914130896 0.895988501 0.865737008 1.051939363 0.910827738 1 13.58629422 -7.541326627 2.310145635 0.985827329 0.912927768 0.033969806 0.056776115 0.255347825 2.756952851 0.009279133 0.009944244 2.88E-08 7.541326627 -0.072899561 KSFSKEELMS(ph)SDLEETAGSTSIPK ddPTM_HeLa_Curcumin_4h_R1 1 KSFSKEELMSSDLEETAGSTSIPK 24 2 O00567 O00567 NOP56 Nucleolar protein 56 1 0 KSFSKEELMS(0.736)S(0.25)DLEET(0.009)AGS(0.002)T(0.003)SIPK 69.649 0.00076633 45135000 1909.9 1456.9 1427.2 1605.9 1477.8 1811.8 1234.4 1205.3 1995.1 1384.9 TRUE FALSE FALSE 1758.7294 1582.827944 1480.093287 1599.255211 1460.1782 1436.012257 1269.033942 1572.790421 1776.242521 1433.025172 1.227284373 1.104536037 1.032845282 1.115999386 1.018948047 1.002084461 0.88556291 1.097531608 1.239505458 1 10.48484824 -5.618109053 2.417327738 1.104499019 0.984233786 0.307034227 0.08529804 0.332056731 3.915529861 0.014449052 0.03294225 2.41E-06 5.618109053 -0.120265233 KSGYSLNFSEGDGR ddPTM_HeLa_Curcumin_4h_R1 1 KSGYSLNFSEGDGR 14 1 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 0 0 30.905 0.020366 87072000 10281 7821.6 10178 9516.6 8544.4 5105.3 6573 7124.1 8089.7 8141.1 FALSE FALSE TRUE 9467.248002 8497.664252 10555.20563 9477.222831 8442.513611 4046.403231 6757.42069 9296.205295 7202.280149 8424.002619 1.123842006 1.008744256 1.252991732 1.125026102 1.00219741 0.480342115 0.8021627 1.103537797 0.854971262 1 13.04029017 -5.503930762 24.67188235 1.07556805 0.786902477 0.326486091 0.170165974 467.7521825 609052.345 0.021884021 0.048174382 3.13E-06 5.503930762 -0.288665573 KSKLET(ph)T(ph)YR ddPTM_HeLa_Curcumin_4h_R1 3 KSKLETTYR 9 2 Q92628 Q92628 KIAA0232 Uncharacterized protein KIAA0232 2 0 KSKLET(0.989)T(0.908)Y(0.103)R;KSKLET(0.997)T(0.887)Y(0.116)R;KSKLET(0.896)T(0.808)Y(0.296)R ;; 82.75 0.0084366 1354870000 8504.32 6543.84 6235.98 7396.92 6045.36 9282.4 6928.7 7071.44 9020.2 7849.96 TRUE FALSE FALSE 7831.194098 7109.460371 6467.090905 7366.313505 5973.27303 7357.125606 7123.100674 9227.489503 8030.706627 8122.745526 0.964106788 0.875253367 0.796170566 0.906874835 0.735376113 0.905743702 0.87693264 1.136006228 0.988668992 1 12.98775173 -7.367051834 3.506772339 0.984854701 0.88144127 0.161340097 0.097499669 0.297813902 6.607379266 0.016659543 0.018966139 4.29E-08 7.367051834 -0.103413431 KSLDS(ph)DES(ph)EDEEDDYQQK ddPTM_HeLa_Curcumin_4h_R1 3 KSLDSDESEDEEDDYQQK 18 1 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 2 0 KS(0.412)LDS(0.604)DES(0.98)EDEEDDY(0.003)QQK;KS(0.452)LDS(0.555)DES(0.993)EDEEDDYQQK;KS(0.101)LDS(0.912)DES(0.97)EDEEDDY(0.018)QQK ;; 88.555 0.0013806 295450000 7687.8 6282.8 6317.2 6873 6747.9 7109.3 6474.7 6588.1 7792.9 6542.2 TRUE FALSE FALSE 7079.302518 6825.857236 6551.320989 6844.561347 6667.4357 5634.751042 6656.362656 8596.781362 6938.038367 6769.540963 1.045758133 1.008319068 0.967764436 1.011082049 0.984916959 0.832368261 0.983281244 1.269920872 1.024890521 1 12.72484229 -7.004011173 22.77252668 1.021893829 0.997322234 0 0.101976317 284.5952051 1615755.62 0.016289276 0.021096643 9.91E-08 7.004011173 -0.024571596 KSLDSDES(ph)EDEEDDYQQK ddPTM_HeLa_Curcumin_4h_R1 1 KSLDSDESEDEEDDYQQK 18 1 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 1 0 KSLDSDES(1)EDEEDDYQQK 102.61 0.00055212 15588000 3103.2 2213.9 2633.8 2933.8 2442.1 2941 2768.6 8230.1 3134.6 2521.3 TRUE FALSE FALSE 2857.578446 2405.259651 2731.410945 2921.660713 2412.979552 2331.003448 2846.279465 10739.4196 2790.742222 2608.914987 1.095312979 0.921938684 1.046952836 1.119875783 0.924897731 0.8934762 1.090982067 4.116431411 1.06969458 1 11.34923422 -4.261557938 6.447081078 1.024755695 4.180073017 0.993682987 0.074127145 0.006465195 1.57581757 0.010620515 0.088697175 5.48E-05 4.261557938 3.155317322 KSLKCEQHMGHRAMY(ph)WY(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 KSLKCEQHMGHRAMYWYK 18 3 A0A577;A0A0J9YWV2 A0A577 TCRBV7S1A1N2T 2 0 KSLKCEQHMGHRAMY(1)WY(1)K 52.026 0.0088155 0 565.12 495.41 512.12 529.72 691.52 615.12 524.19 731.76 685.52 709.15 TRUE FALSE FALSE 520.3901557 538.2310329 531.0996177 527.528159 683.2740756 487.5371782 538.8973606 954.8702554 610.3201711 733.7929097 0.709178501 0.733491733 0.723773166 0.718906046 0.931153826 0.664407044 0.734399792 1.301280297 0.831733535 1 9.519229154 -4.255298748 24.57077607 0.817588993 1.301280571 0.669315229 0.106827387 339.5804803 1358728.174 0.0192563 0.23580963 5.56E-05 4.255298748 0.483691578 KSLS(ph)DSESDDSK ddPTM_HeLa_Curcumin_4h_R1 1 KSLSDSESDDSK 12 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 0 KS(0.06)LS(0.903)DS(0.025)ES(0.001)DDS(0.01)K 82.651 0.0077318 0 794.02 666.44 672.13 479.65 575.65 562.28 519.75 504.76 595.21 494.93 TRUE FALSE FALSE 731.1724792 724.044104 697.0397291 477.6653354 568.7857497 445.6567898 534.3327862 658.6590004 529.9169521 512.1287807 1.427712143 1.413793037 1.36106338 0.93270551 1.110630316 0.87020454 1.043356293 1.286119869 1.034733786 1 9.000362828 -6.258816327 24.9859742 1.237208656 1.04184671 0.255512684 0.169071978 322.457882 3071574.214 0.031248457 0.050294715 5.51E-07 6.258816327 -0.195361946 KSLSDS(ph)ESDDSK ddPTM_HeLa_Curcumin_4h_R1 1 KSLSDSESDDSK 12 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 0 KSLS(0.213)DS(0.726)ES(0.03)DDS(0.03)K 176.43 0.00022276 458870000 3471.2 3032.2 2991.9 2599 2468.5 2941.2 2316.4 1328.2 2763.4 2986.3 TRUE FALSE FALSE 3196.450857 3294.289857 3102.782446 2588.246027 2439.06475 2331.161966 2381.39195 1733.162066 2460.261934 3090.073703 1.034425442 1.066087794 1.004112764 0.837600095 0.789322516 0.754403354 0.770658625 0.560880494 0.796182282 1 11.59342553 -5.783791537 1.011930636 1.02347421 0.674904349 0.646302187 0.0904727 0.134569758 0.265501309 0.009246223 0.028158781 1.65E-06 5.783791537 -0.348569861 QTAEETGLTPLETS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 QTAEETGLTPLETSR 15 0 Q5T8C6;Q13042-4;Q13042-3;Q13042-2;Q13042 Q5T8C6 CDC16 Cell division cycle protein 16 homolog 1 0 QTAEETGLTPLET(0.296)S(0.704)R;QTAEETGLTPLET(0.055)S(0.945)R ; 118.05 0.0014704 12434600 5502.2 5318.6 4435.9 5335.2 5297.2 7090.6 4020.5 1825.12 5671 5413.9 TRUE FALSE FALSE 5066.695064 5778.316085 4600.298356 5313.124356 5234.03435 5619.929632 4133.304409 2381.590686 5048.905488 5602.032622 0.904438693 1.031467768 0.821183786 0.948427957 0.934309866 1.003194735 0.737822267 0.425129743 0.901263136 1 12.45173467 -4.401474682 2.453744682 0.950579922 0.381539739 0.875568681 0.06016618 0.09249565 0.828390771 0.00835614 0.095851277 3.97E-05 4.401474682 -0.569040183 down KSLSPGVS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 KSLSPGVSR 9 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 KSLS(0.161)PGVS(0.839)R 92.838 0.0059962 0 1269.4 1200.6 1402.3 1032.5 1911.2 2400.6 1819 1466 1705.7 1384.2 TRUE FALSE FALSE 1168.925651 1304.374514 1454.270472 1028.227789 1888.410188 1902.6885 1870.036244 1912.976651 1518.588977 1432.300847 0.816117405 0.910684733 1.015338694 0.717885346 1.318445208 1.328414002 1.305616937 1.335596956 1.060244418 1 10.48411884 -5.743949603 24.96550423 0.907247156 1.321303775 0.814014935 0.094009857 70.4261129 100528.0833 0.013215969 0.026383707 1.80E-06 5.743949603 0.414056619 KSNLDEEVNVIPPHT(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 4 KSNLDEEVNVIPPHTPVR 18 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 0 KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR;KSNLDEEVNVIPPHT(1)PVR ;;; 89.721 0.0015488 47518400 14960.6 12506.8 14253 16279.4 14564.7 19605.1 16489.6 12506.8 16162.1 15357.3 TRUE FALSE FALSE 13776.45272 13587.83206 14781.22872 16212.04016 14391.02547 15538.78126 16952.2538 16320.06575 14389.15807 15890.96503 0.866936193 0.855066513 0.930165581 1.020204885 0.905610543 0.977837484 1.066785671 1.02700281 0.905493029 1 13.95591912 -4.946989063 4.112649897 0.933630917 1.045757324 0.475747044 0.050019972 0.17993848 6.349128819 0.008849098 0.028290163 1.13E-05 4.946989063 0.112126407 KSPGGGGGGGSGNDNNQAATK(ac)SPR ddPTM_HeLa_Curcumin_4h_R1 2 KSPGGGGGGGSGNDNNQAATKSPR 24 2 Q9NS37;E9PIM0;J3KN20 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 0 1 ; KSPGGGGGGGSGNDNNQAATK(1)SPR;KSPGGGGGGGSGNDNNQAATK(1)SPR 188.39 2.98E-12 1588090 433.53 523.9 302.87 536.75 448 612.63 255.7 122.23 484.4 595.71 FALSE TRUE FALSE 399.215643 569.1835815 314.0946286 534.5290707 442.6578926 485.5636322 262.8742538 159.4973643 431.2625319 616.4108782 0.647645357 0.923383415 0.509554 0.867163591 0.718121481 0.787727228 0.426459466 0.258751703 0.699634849 1 9.267748512 -5.024959754 0.115782476 1.153782113 3.00E-33 0.34004487 0.178314906 21.75349839 0.557735793 1.444302853 4.665976508 9.44E-06 5.024959754 -1.153782113 KSPS(ph)GPVKSPPLSPVGTTPVK ddPTM_HeLa_Curcumin_4h_R1 1 KSPSGPVKSPPLSPVGTTPVK 21 2 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 0 KS(0.034)PS(0.456)GPVKS(0.325)PPLS(0.17)PVGT(0.006)T(0.008)PVK 64.26 0.0046906 39806000 3749.6 2550.3 3032.6 3160.5 2827.6 4230.8 3908.1 5100.1 3346.9 3554.1 TRUE FALSE FALSE 3452.815203 2770.736568 3144.990824 3147.422688 2793.882717 3353.284389 4017.750768 6655.097012 2979.753444 3677.60471 0.93887611 0.753407934 0.855173699 0.855834962 0.759701745 0.911812077 1.092491196 1.809628151 0.810242992 1 11.8445507 -4.257440864 2.641149379 0.920652996 1.995066952 0.905683345 0.090446563 0.120826284 1.079727828 0.014430647 0.286413484 5.53E-05 4.257440864 1.074413956 KSPSGPVKS(ph)PPLSPVGTTPVK ddPTM_HeLa_Curcumin_4h_R1 1 KSPSGPVKSPPLSPVGTTPVK 21 2 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 0 KS(0.002)PS(0.078)GPVKS(0.453)PPLS(0.453)PVGT(0.01)T(0.004)PVK 59.857 0.0087303 22489000 2137 2246.5 1774.9 1871.6 1868.3 3114.2 2610.7 3339 2778.2 2288.6 TRUE FALSE FALSE 1967.854195 2440.67745 1840.679355 1863.855815 1846.021743 2468.279816 2683.949216 4357.045729 2473.438411 2368.12868 0.830974352 1.030635485 0.777271679 0.787058504 0.779527632 1.042291256 1.133362912 1.839868655 1.044469598 1 11.20953176 -4.090035985 1.537547467 0.899747158 2.525402421 0.87960762 0.10368446 0.406092431 0.638271435 0.015175685 1.123098584 8.13E-05 4.090035985 1.625655263 KSPSLESLS(ph)RPPSLGFGDTR ddPTM_HeLa_Curcumin_4h_R1 1 KSPSLESLSRPPSLGFGDTR 20 2 Q5M775-4;Q5M775;J3KSG2 Q5M775-4 SPECC1 Cytospin-B 1 0 KS(0.025)PS(0.212)LES(0.212)LS(0.551)RPPS(0.001)LGFGDTR 59.789 0.012488 116740000 1117.6 995.05 1147.2 876.92 970.41 1491.5 1001.2 426.39 1304.8 1231.3 TRUE FALSE FALSE 1029.140781 1081.057688 1189.716241 873.2915374 958.8384945 1182.146087 1029.290977 556.3943481 1161.666704 1274.087583 0.807747281 0.848495584 0.933779009 0.685425044 0.752568746 0.927837382 0.807865166 0.436700236 0.911763618 1 10.31524874 -2.169435874 0.080329892 1.177358573 1.77E-17 0.407614849 0.118065152 109.9350444 0.823853439 2.296414851 14.83898463 0.006769617 2.169435874 -1.177358573 KSPSSDS(ph)WTCADTSTER ddPTM_HeLa_Curcumin_4h_R1 1 KSPSSDSWTCADTSTER 17 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 0 KS(0.001)PS(0.001)S(0.001)DS(0.996)WT(0.002)CADTSTER 200.9 2.63E-10 7013900 1096.3 1097.7 994.63 798.6 1019.1 1148.4 736.84 1414.2 1028.9 814.8 TRUE FALSE FALSE 1009.526698 1192.580297 1031.491863 795.2956048 1006.947898 910.2088949 757.5137473 1845.38307 916.0322442 843.1142394 1.197378304 1.414494313 1.223430722 0.943283327 1.194319644 1.079579554 0.898471064 2.188769901 1.086486506 1 9.719584315 -4.254489873 24.99441284 1.111144213 2.188770398 0.834038746 0.143648396 252.9300422 909658.4882 0.021123245 0.281403323 5.57E-05 4.254489873 1.077626185 KSPSSDSWTCADTS(ph)TER ddPTM_HeLa_Curcumin_4h_R1 1 KSPSSDSWTCADTSTER 17 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 0 KSPSSDSWT(0.002)CADT(0.02)S(0.489)T(0.489)ER 101.01 0.00093332 30537000 3589.4 2775.6 2576.7 3699.9 3893.8 114.5 860.29 910.21 3033.5 2396.7 TRUE FALSE FALSE 3305.295202 3015.510496 2672.194769 3684.590794 3847.368978 90.75140932 884.427422 1187.728839 2700.732639 2479.985147 1.332788306 1.215938934 1.077504344 1.485730993 1.55136775 0.036593529 0.356626096 0.478925787 1.089011619 1 11.27611576 -5.258232872 24.99989862 1.206942115 0.297306209 0.831122574 0.197543205 94.08746695 733558.6629 0.031244938 0.076129998 5.52E-06 5.258232872 -0.909635906 KSPVGKS(ph)PPSTGSTYGSSQK ddPTM_HeLa_Curcumin_4h_R1 1 KSPVGKSPPSTGSTYGSSQK 20 2 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 KS(0.16)PVGKS(0.838)PPS(0.001)T(0.001)GSTYGSSQK 72.21 0.0016209 24157000 5052.4 5001.5 4498.3 4753 5830.5 5062.6 4807.3 2912.8 5020.3 4856.3 TRUE FALSE FALSE 4652.497209 5433.807374 4665.010955 4733.333345 5760.975096 4012.559693 4942.1799 3800.899311 4469.58565 5025.056064 0.925859762 1.081342637 0.928350032 0.941946375 1.146449915 0.798510433 0.983507415 0.756389434 0.889459857 1 12.29492398 -3.488299809 1.118571567 0.974687041 7.40E-14 0.308931687 0.092737903 6.669421419 1.899527356 0.012186263 11.65620226 0.000324863 3.488299809 -0.974687041 SEPAVVS(ph)LEYGVAR ddPTM_HeLa_Curcumin_4h_R1 2 SEPAVVSLEYGVAR 14 0 Q9Y217 Q9Y217 MTMR6 Myotubularin-related protein 6 1 0 SEPAVVS(1)LEYGVAR;SEPAVVS(1)LEYGVAR ; 219.84 4.55E-14 15647800 1862.36 1497.36 1887.76 1738.32 1740.38 1977.75 2262.54 3703.9 1739.31 1515.98 TRUE FALSE FALSE 1714.952241 1626.785126 1957.722046 1731.127292 1719.627105 1567.542356 2326.020783 4833.202059 1548.512045 1568.660192 1.093259234 1.037053872 1.248021755 1.103570615 1.096239398 0.999287394 1.482807299 3.081102003 0.987155824 1 10.61531715 -4.25816487 2.554388295 1.064793271 3.522512773 0.98445328 0.075608536 0.042706085 0.347623067 0.011002686 0.226435163 5.52E-05 4.25816487 2.457719501 up KSS(ph)PEMEDAR ddPTM_HeLa_Curcumin_4h_R1 2 KSSPEMEDAR 10 1 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 0 KS(0.028)S(0.972)PEMEDAR;KS(0.013)S(0.987)PEMEDAR ; 161.25 0.00095702 28440900 5479.9 4195.5 4310.7 4759.6 4481.4 5321.9 4366.8 3301.6 5225.8 4798 TRUE FALSE FALSE 5046.160133 4558.140325 4470.458334 4739.906036 4427.962232 4218.07795 4489.320655 4308.242641 4652.542814 4964.730143 1.016401695 0.918104347 0.900443369 0.954715745 0.891883769 0.849608705 0.904242633 0.867769751 0.937118973 1 12.27749959 -7.172973021 3.769431801 1.007886297 0.896564209 0.549866888 0.034300343 0.07725554 2.057722606 0.004587679 0.005627402 6.71E-08 7.172973021 -0.111322088 KSS(ph)PKSS(ph)S(ph)AS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 KSSPKSSSASK 11 2 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 4 0 KS(0.446)S(0.56)PKS(0.298)S(0.852)S(0.85)AS(0.993)K 77.776 0.0053707 0 1890.1 1503.8 1458.3 1669.4 1462.4 1920.8 1382.5 1511.9 1755.7 1402.5 TRUE FALSE FALSE 1740.496591 1633.781771 1512.345881 1662.492465 1444.961835 1522.404428 1421.289229 1972.87135 1563.104103 1451.236771 1.199319522 1.125785815 1.042108298 1.14556942 0.995676146 1.049039315 0.979364124 1.359441402 1.077084136 1 10.5030672 -9.657134965 1.518976913 1.000355146 1.116159819 0.052063011 0.107431839 0.630231728 2.628699486 0.072401328 0.016521533 2.20E-10 9.657134965 0.115804673 KSSADT(ph)EFSDECTTAER ddPTM_HeLa_Curcumin_4h_R1 1 KSSADTEFSDECTTAER 17 1 Q9H6S0 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 1 0 KS(0.004)S(0.479)ADT(0.517)EFS(0.001)DECTTAER 170 0.00067972 8810300 1696.1 1310.3 1586.2 1684.9 1752.7 1958.3 1720.3 2943 1788.2 1945.5 TRUE FALSE FALSE 1561.851895 1423.556493 1644.985967 1677.92833 1731.800197 1552.126505 1768.566988 3840.307152 1592.038934 2013.10598 0.775841864 0.707144337 0.817138285 0.833502233 0.860262805 0.771010826 0.878526518 1.907652746 0.790837119 1 10.97520741 -4.261693198 6.756296472 0.858664854 1.925530541 0.941847095 0.080276399 0.024830636 7.673678537 0.014703098 0.120671484 5.47E-05 4.261693198 1.066865687 KSSEAS(ph)PTAQR ddPTM_HeLa_Curcumin_4h_R1 1 KSSEASPTAQR 11 1 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 0 KSSEAS(0.77)PT(0.23)AQR 122.52 0.0060977 2061300 678.16 998.78 659.15 556.26 403.48 653.61 415.84 338.85 775.4 653.63 TRUE FALSE FALSE 624.4829204 1085.110093 683.5786788 553.9583435 398.6687645 518.0439183 427.5073512 442.1638051 690.34056 676.3435938 0.923322001 1.60437698 1.010697351 0.819048703 0.589447092 0.765947845 0.632086051 0.653756181 1.020695052 1 9.401612536 -6.072478401 3.408531085 1.023546052 0.667484441 0.533899868 0.191507972 0.191029027 4.317052588 0.030983343 0.054558307 8.46E-07 6.072478401 -0.356061611 KSSEGGVGVGPGGGDEPPT(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 KSSEGGVGVGPGGGDEPPTSPR 22 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 KSSEGGVGVGPGGGDEPPT(0.5)S(0.5)PR 78.456 0.00049337 28792000 3394.2 2553.8 3200.8 3043.1 2696.5 3608.1 3058.8 2894.4 3250 2985.1 TRUE FALSE FALSE 3125.545488 2774.539092 3319.424464 3030.508459 2664.345999 2859.739388 3144.621696 3776.889236 2893.483131 3088.832003 1.01188588 0.898248623 1.07465361 0.981117929 0.862573943 0.92583196 1.018061744 1.222756444 0.936756395 1 11.59284569 -4.275891906 3.994390735 0.986355386 1.240930362 0.597293149 0.061621975 0.122255074 4.029111754 0.008479472 0.087704571 5.30E-05 4.275891906 0.254574977 KSSEGGVGVGPGGGDEPPTS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 KSSEGGVGVGPGGGDEPPTSPR 22 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 KSSEGGVGVGPGGGDEPPT(0.385)S(0.615)PR 109.4 1.38E-05 13909000 4061.7 3350.3 3670.9 3659 3684.1 4682.9 4324.3 3081 4202.3 3754.9 TRUE FALSE FALSE 3740.212159 3639.885003 3806.946783 3643.860028 3640.169514 3711.613753 4445.62822 4020.382717 3741.318204 3885.382496 0.962636797 0.936815103 0.979812615 0.937838175 0.936888329 0.955276284 1.144193197 1.034745671 0.962921465 1 11.92384092 -4.77338736 24.99969258 0.970691209 1.089469438 0.710222751 0.032655796 83.44727419 174604.4949 0.004756989 0.014432723 1.69E-05 4.77338736 0.118778229 KSSGEIVYCGQVFEKS(ph)PLR ddPTM_HeLa_Curcumin_4h_R1 1 KSSGEIVYCGQVFEKSPLR 19 2 M0R0P7;M0R3D6;M0R1A7;M0R117;Q02543 M0R0P7 RPL18A 60S ribosomal protein L18a 1 0 KSSGEIVYCGQVFEKS(1)PLR 92.518 0.0012094 19398000 3053.7 2700 2656.5 3269.4 2620.3 3387.2 2339.5 2111 3521.2 2603.5 TRUE FALSE FALSE 2811.996423 2933.375969 2754.952227 3255.872089 2589.054634 2684.656538 2405.140074 2754.634182 3134.93317 2693.971431 1.043810781 1.088866769 1.022636022 1.208577066 0.96105497 0.996542319 0.892786035 1.022517964 1.163684638 1 11.39551884 -5.618099532 20.75769015 1.040598824 0.964759684 0.267466806 0.075646829 4.999433511 1081.828952 0.009464507 0.018929023 2.41E-06 5.618099532 -0.07583914 KSSPST(ph)GSLDSGNESK ddPTM_HeLa_Curcumin_4h_R1 1 KSSPSTGSLDSGNESK 16 1 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2" 1 0 KSS(0.003)PS(0.276)T(0.713)GS(0.008)LDSGNESK 149.41 0.0035241 9531800 2524 1987 2350.5 2456 2614.1 3269 2742.5 2289.6 2362.4 2309.6 TRUE FALSE FALSE 2324.222737 2158.747426 2437.611598 2445.837723 2582.928565 2590.972551 2819.447169 2987.6885 2103.25063 2389.858428 0.972535741 0.903295108 1.019981589 1.023423687 1.080787269 1.084153153 1.179754891 1.250152923 0.880073316 1 11.22270944 -4.650484838 0.704333663 0.981129864 1.337491875 0.829524909 0.044926332 0.442553451 0.208659423 0.005777968 0.112262513 2.24E-05 4.650484838 0.356362011 KSST(ph)PEEVK ddPTM_HeLa_Curcumin_4h_R1 1 KSSTPEEVK 9 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 0 KSS(0.187)T(0.813)PEEVK 108.9 0.0033392 0 2039.6 4450.3 1864.4 2429.8 1281.8 1650.6 1817.6 1141 1421.6 1651.3 TRUE FALSE FALSE 1878.163508 4834.964102 1933.496304 2419.746131 1266.515372 1308.246954 1868.596964 1488.885647 1265.654037 1708.682552 1.099188088 2.829644451 1.131571398 1.41614727 0.741223331 0.765646581 1.093589305 0.871364693 0.740719237 1 10.73866868 -5.756036953 24.99848078 1.226639393 0.876764819 0.138329375 0.547363229 283.0712506 1309831.675 0.081681386 0.15964764 1.75E-06 5.756036953 -0.349874575 KSST(ph)SGSDFDTK ddPTM_HeLa_Curcumin_4h_R1 1 KSSTSGSDFDTK 12 1 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6;A0A096LNW1 P46100-5 ATRX Transcriptional regulator ATRX 1 0 KS(0.001)S(0.042)T(0.85)S(0.078)GS(0.026)DFDT(0.003)K 148.57 0.0064679 14301000 2315.2 2011.1 2166.1 2250.8 2024.2 2175.6 1716.2 2037.1 2358.4 2030.7 TRUE FALSE FALSE 2131.949477 2184.930523 2246.377571 2241.486786 2000.062737 1724.356036 1764.351953 2658.202412 2099.68942 2101.266674 1.014602051 1.039815912 1.069058773 1.066731231 0.9518367 0.820626938 0.839661132 1.265047624 0.99924938 1 11.03704355 -5.684445355 10.71743479 1.018706774 0.94922613 0.047562883 0.115897664 0.928490894 123.6749476 0.015864292 0.031736289 2.07E-06 5.684445355 -0.069480645 KSSTPEEVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 KSSTPEEVKK 10 2 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 1 KSSTPEEVK(1)K 114.76 0.00088043 4169200 2847 2737.7 2325.7 2656.5 2622 3429.1 2396.6 2369.9 3210.8 2209.1 FALSE TRUE FALSE 2621.656946 2974.334589 2411.892488 2645.508107 2590.734362 2717.866006 2463.842146 3092.4716 2858.583273 2285.866061 1.146898758 1.301184982 1.055132901 1.157332948 1.133371026 1.188987427 1.077859367 1.352866493 1.250547144 1 11.15852516 -8.875840255 0.647672293 0.992475212 1.173485245 0 0.116032969 0.661549731 0.501414768 0.063483187 0.018689823 1.33E-09 8.875840255 0.181010033 KSSTVATLQGT(ph)PDHGDPR ddPTM_HeLa_Curcumin_4h_R1 1 KSSTVATLQGTPDHGDPR 18 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 KSSTVATLQGT(1)PDHGDPR 92.792 0.0011192 0 1356.9 1346.4 1078.5 1257.3 1447.3 2196.4 1989.8 1305.1 1757.5 1009.6 TRUE FALSE FALSE 1249.499933 1462.776817 1118.470159 1252.097626 1430.041893 1740.841881 2045.628433 1703.018982 1564.706647 1044.683525 1.196055938 1.400210477 1.070630609 1.198542521 1.368875701 1.666382057 1.958132185 1.630176931 1.497780533 1 10.02885024 -5.39724046 1.741695803 1.121824656 1.806400805 0.619925522 0.174005075 0.11468782 0.669547787 0.02108415 0.063447959 4.01E-06 5.39724046 0.684576149 TQT(ph)PPVEENVTQK ddPTM_HeLa_Curcumin_4h_R1 1 TQTPPVEENVTQK 13 0 Q6P1Q9;Q6P1Q9-2 Q6P1Q9 METTL2B Methyltransferase-like protein 2B 1 0 TQT(1)PPVEENVTQK 191.63 2.06E-05 40180000 2739.1 3143.3 3087.1 3064.9 2988.2 3750.9 2999.6 5620.3 2750 2632.6 TRUE FALSE FALSE 2522.297345 3414.992846 3201.510642 3052.218256 2952.567667 2972.921059 3083.760703 7333.903597 2448.33188 2724.082654 0.925925409 1.253630407 1.175261932 1.120457285 1.083875947 1.091347597 1.132036393 2.69224709 0.898772978 1 11.41155476 -4.258037251 4.30844985 1.02827202 2.821520502 0.952752513 0.107774975 0.035052267 1.513333055 0.017214628 0.192609706 5.52E-05 4.258037251 1.793248481 up AAAGPLDMS(ph)LPST(ph)PDIK ddPTM_HeLa_Curcumin_4h_R1 1 AAAGPLDMSLPSTPDIK 17 0 K7ELQ4;P17544-4;P17544-2;P17544 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 2 0 AAAGPLDMS(0.999)LPS(0.199)T(0.802)PDIK 115.91 0.006187 12133000 2919.8 2049.5 2390.1 2729.3 2341.8 3158.3 3647.4 5202.7 2868.6 2122.5 TRUE FALSE FALSE 2688.694749 2226.649648 2478.679209 2718.00688 2313.875564 2503.232979 3749.736228 6788.97928 2553.921757 2196.256717 1.224216973 1.013838515 1.128592659 1.237563377 1.053554235 1.139772486 1.707330568 3.091159256 1.16285211 1 11.10083098 -4.258007256 1.933218233 1.107424743 3.717741713 0.982952438 0.078694863 0.08253973 0.315951424 0.013768476 0.38502036 5.52E-05 4.258007256 2.610316971 up KSVAEGLSGS(ph)LVQEPFQLATEK ddPTM_HeLa_Curcumin_4h_R1 1 KSVAEGLSGSLVQEPFQLATEK 22 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 0 KS(0.004)VAEGLS(0.185)GS(0.811)LVQEPFQLATEK 82.65 0.00034047 11949000 2329.7 1953.7 2069.7 2752.7 2408.2 2717.1 2639 863.26 2471.3 1500.3 TRUE FALSE FALSE 2145.301787 2122.569122 2146.404903 2741.310057 2379.483788 2153.542832 2713.043237 1126.464 2200.204573 1552.435313 1.381894478 1.36725125 1.382605049 1.765812742 1.532742632 1.387202941 1.747604692 0.72561091 1.417260065 1 10.60031744 -8.832902039 0.620171658 0.982547844 1.446883825 0 0.298524465 0.844300919 0.591263657 0.202587253 0.06044777 1.47E-09 8.832902039 0.464335981 VNPVTSLSENYTCS(ph)DSEESSEKDKLAIPK ddPTM_HeLa_Curcumin_4h_R1 2 VNPVTSLSENYTCSDSEESSEKDKLAIPK 29 2 Q14432 Q14432 PDE3A "cGMP-inhibited 3,5-cyclic phosphodiesterase A" 1 0 VNPVTSLS(0.004)ENY(0.066)T(0.196)CS(0.505)DS(0.143)EES(0.043)S(0.043)EKDKLAIPK;VNPVTSLSENY(0.001)T(0.018)CS(0.755)DS(0.159)EES(0.054)S(0.012)EKDKLAIPK ; 112.28 3.04E-11 635620000 6272.2 4526.6 4690.9 5207.8 3731.3 5776.2 3487.7 1001.47 6576.9 5512.3 TRUE FALSE FALSE 5775.748752 4917.859134 4864.748881 5186.251503 3686.806684 4578.151009 3585.555475 1306.813593 5855.430525 5703.852015 1.012604944 0.862199637 0.852888341 0.909254218 0.646371378 0.802641968 0.628620004 0.229110711 1.026574762 1 12.47772084 -4.40057916 0.47803898 1.003780338 7.31E-17 0.833139041 0.094389962 1.092853902 0.18212426 0.020306936 0.600475263 3.98E-05 4.40057916 -1.003780338 down NYS(ph)SPPPCHLSR ddPTM_HeLa_Curcumin_4h_R1 1 NYSSPPPCHLSR 12 0 Q12986-3;Q12986-2;Q12986 Q12986-3 NFX1 Transcriptional repressor NF-X1 1 0 NY(0.324)S(0.352)S(0.324)PPPCHLSR 71.513 0.016614 7809400 2706.1 2047.9 1999.9 2039.6 2199.6 3596.7 1871.4 849.6 2756.5 2434.4 TRUE FALSE FALSE 2491.90933 2224.911351 2074.018053 2031.160676 2173.371207 2850.703877 1923.906447 1108.639129 2454.118846 2518.995219 0.989247344 0.883253503 0.823351326 0.806337646 0.862792907 1.131682925 0.763759468 0.440111645 0.974245139 1 11.29863267 -4.400544838 3.239547409 0.959085189 0.430740823 0.700775522 0.096768794 0.114307397 1.945501611 0.014566019 0.12184589 3.98E-05 4.400544838 -0.528344366 down KT(ph)LDELSQGTTTVK ddPTM_HeLa_Curcumin_4h_R1 1 KTLDELSQGTTTVK 14 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 1 0 KT(0.999)LDELS(0.001)QGTTTVK 167.18 0.0021095 17297000 950.27 828.32 823.97 923.42 1031.2 5888.2 5620.5 845.63 1230.3 926.18 TRUE FALSE FALSE 875.0551268 899.9162899 854.507053 919.5991327 1018.903613 4666.920946 5778.196103 1103.458694 1095.339168 958.3646861 0.91307113 0.939012364 0.891630363 0.959550311 1.063168988 4.869671237 6.029224769 1.15139749 1.142925218 1 9.904430938 -5.269985086 24.04852248 0.957414487 4.218010538 0.592617049 1.147315296 154.1806313 433881.5433 0.146343544 0.332481663 5.37E-06 5.269985086 3.260596052 KT(ph)PPAPSPFDLPELK ddPTM_HeLa_Curcumin_4h_R1 2 KTPPAPSPFDLPELK 15 1 O95239 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 0 KT(1)PPAPSPFDLPELK;KT(0.999)PPAPS(0.001)PFDLPELK ; 110.37 0.001147 42306000 7026.6 6307.7 6406.4 7107.6 7578.9 8577.1 6392 2574.37 6535.8 5400.9 TRUE FALSE FALSE 6470.437196 6852.909481 6643.82682 7078.190634 7488.526567 6798.112776 6571.342317 3359.283562 5818.839092 5588.580873 1.15779611 1.226234287 1.188821808 1.266545264 1.339969258 1.216429167 1.175851699 0.601097781 1.041201554 1 12.44826627 -1.372524727 15.20626263 1.114047332 0.008547272 0 0.197514503 0 0 0.025697533 0 0.042410684 1.372524727 -1.10550006 KT(ph)SPASLDFPESQK ddPTM_HeLa_Curcumin_4h_R1 1 KTSPASLDFPESQK 14 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 KT(0.63)S(0.369)PAS(0.001)LDFPESQK 79.462 0.010255 198830000 3777.7 2843.7 3609.1 3507.5 3139.6 3817.9 2299.9 1671.8 3855 3369.1 TRUE FALSE FALSE 3478.691059 3089.496757 3742.856421 3492.986894 3102.162321 3026.024503 2364.429004 2181.524124 3432.116145 3486.175974 0.997852973 0.886213656 1.073628081 1.001953694 0.889846739 0.868006815 0.678229964 0.625764201 0.984493086 1 11.76742968 -4.841342019 1.1422768 0.99567945 0.577493544 0.877482529 0.048621466 0.161261793 0.302963976 0.007013615 0.062831565 1.44E-05 4.841342019 -0.418185906 KT(ph)SQSEEEEAPR ddPTM_HeLa_Curcumin_4h_R1 1 KTSQSEEEEAPR 12 1 Q7RTP6;A0A5F9ZHV5;J3KSK6;Q7RTP6-2;Q7RTP6-4;Q7RTP6-3;Q7RTP6-5 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 0 KT(0.972)S(0.028)QSEEEEAPR 78.529 0.01365 12908000 1049.6 1294.1 902.22 1328.4 1761.9 1761.5 1224.2 2040.8 2064.9 1817 TRUE FALSE FALSE 966.5230525 1405.956238 935.6570669 1322.903433 1740.890493 1396.145044 1258.547757 2663.030525 1838.385636 1880.140615 0.514069557 0.747793131 0.497652707 0.703619411 0.925936326 0.742574802 0.669390229 1.416399659 0.977791566 1 10.87662485 -4.25743399 24.71596687 0.7455288 1.416399966 0.590775746 0.165478627 218.8066419 1350120.992 0.027371107 0.278607408 5.53E-05 4.25743399 0.670871166 KT(ph)SSDDES(ph)EEDEDDLLQR ddPTM_HeLa_Curcumin_4h_R1 1 KTSSDDESEEDEDDLLQR 18 1 Q9Y5J1 Q9Y5J1 UTP18 U3 small nucleolar RNA-associated protein 18 homolog 2 0 KT(0.354)S(0.295)S(0.354)DDES(0.997)EEDEDDLLQR 79.942 0.0048135 365420000 4641.4 3743.1 4129.2 4114.3 4377.1 4730.8 3780.8 3512.9 4990.4 4231.4 TRUE FALSE FALSE 4274.028292 4066.636885 4282.231784 4097.276117 4324.905941 3749.578753 3886.879072 4583.967039 4442.965605 4378.440835 0.976153031 0.928786533 0.978026641 0.935784283 0.987773069 0.856373055 0.887731322 1.0469405 1.014736929 1 12.0962015 -7.478761322 0.580414666 0.997724461 0.936184704 0.172712021 0.050657203 0.883158732 0.68421053 0.017496528 0.017466884 3.32E-08 7.478761322 -0.061539757 KTEAPAAPAAQET(ph)KSDGAPASDSKPGSSEAAPSSK ddPTM_HeLa_Curcumin_4h_R1 2 KTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSK 35 3 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 1 0 KT(0.001)EAPAAPAAQET(0.683)KS(0.224)DGAPAS(0.063)DS(0.017)KPGS(0.006)S(0.006)EAAPSSK;KTEAPAAPAAQET(0.697)KS(0.265)DGAPAS(0.024)DS(0.008)KPGS(0.003)S(0.003)EAAPSSK ; 53.002 0.00080728 107121800 3667.4 2447.7 3210.9 3582.3 3004.6 4482.5 3649.7 3077.4 4604.9 3014.8 TRUE FALSE FALSE 3377.12142 2659.268281 3329.898779 3567.477392 2968.772107 3552.778972 3752.100759 4015.685093 4099.753991 3119.564076 1.082561966 0.852448681 1.067424389 1.143582022 0.951662487 1.138870331 1.202764447 1.28725841 1.314207335 1 11.60712873 -4.809889155 1.879769577 1.030390845 1.276918214 0.263480035 0.118110653 0.211487222 1.36571963 0.011047174 0.062573814 1.55E-05 4.809889155 0.246527369 KTEAPAAPAAQETK ddPTM_HeLa_Curcumin_4h_R1 1 KTEAPAAPAAQETK 14 1 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 0 0 153.2 0.0002747 9873700 6274.6 5508.7 5535.4 7174.3 6353.2 9085.1 7404 7607.7 8732.6 6479 FALSE FALSE TRUE 5777.958789 5984.847482 5740.546793 7144.614648 6277.442239 7200.74785 7611.736313 9927.252708 7774.655628 6704.144768 0.86184875 0.892708569 0.856268322 1.065701129 0.936352429 1.074074039 1.135377677 1.480763476 1.159678959 1 12.71083759 -2.076056349 0.695542134 0.928715319 13.49486004 0.721594985 0.094188383 13.24219506 0.340038014 0.011537967 238.0767034 0.008393511 2.076056349 12.56614472 KTEAPAAPAAQETKS(ph)DGAPASDSKPGSSEAAPSSK ddPTM_HeLa_Curcumin_4h_R1 1 KTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSK 35 3 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 1 0 KTEAPAAPAAQET(0.328)KS(0.41)DGAPAS(0.177)DS(0.061)KPGS(0.011)S(0.011)EAAPSSK 54.53 0.00028056 115230000 4325.1 2899.7 3602.9 3886.2 3581.8 4994.5 4141.7 3594.2 5317.1 3808.6 TRUE FALSE FALSE 3982.763771 3150.337147 3736.426643 3870.119934 3539.089374 3958.5844 4257.904955 4690.055034 4733.827433 3940.948567 1.010610442 0.799385502 0.948103377 0.982027517 0.898029831 1.004475023 1.080426421 1.190082782 1.201189854 1 11.94432721 -4.498701793 2.080203347 0.976447188 1.201532461 0.32891498 0.095380465 0.291194021 1.930736305 0.009939458 0.101788536 3.17E-05 4.498701793 0.225085273 KTEFLDLDNSPLSPPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 KTEFLDLDNSPLSPPSPR 18 1 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 0 KTEFLDLDNSPLS(0.001)PPS(0.999)PR 131.94 0.0001142 16871000 1869.4 2493.3 2203.4 2212 2345 2769 2595.5 2188.9 2323.5 1935.4 TRUE FALSE FALSE 1721.435017 2708.809742 2285.059942 2202.84733 2317.037407 2194.678187 2668.322745 2856.285534 2068.617863 2002.655006 0.859576418 1.352609278 1.14101527 1.09996346 1.156982805 1.095884304 1.332392617 1.426249416 1.032937704 1 10.9676982 -1 0.231157064 0.921554108 3.777437575 0.422366607 0.126433907 27.90206902 0.3399773 0.092701512 30.51696286 0.1 1 2.855883466 KTETQEK(ac)NPLPSK ddPTM_HeLa_Curcumin_4h_R1 2 KTETQEKNPLPSK 13 2 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 1 ; KTETQEK(1)NPLPSK;KTETQEK(1)NPLPSK 153.32 3.34E-05 43331000 14331.3 18047.2 13629.1 13009.2 25740 31691 25028 23781 29883 13809.6 FALSE TRUE FALSE 13196.96248 19607.11955 14134.20644 12955.37138 25433.06731 25117.92937 25730.21832 31031.71743 26604.90966 14289.48257 0.923543761 1.372136426 0.989133537 0.906636844 1.779845224 1.757791386 1.800640309 2.171647383 1.861852557 1 13.80266606 -5.721998245 5.775255498 0.99525585 1.873145471 0.492895936 0.319248816 0.047647592 3.969507015 0.024103657 0.04800551 1.90E-06 5.721998245 0.877889621 KTETQEK(ac)NPLPSKETIEQEK ddPTM_HeLa_Curcumin_4h_R1 1 KTETQEKNPLPSKETIEQEK 20 3 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 1 K(0.002)TETQEK(0.616)NPLPSK(0.382)ETIEQEK 81.643 0.0017826 12461000 3141.3 3520.3 1868.2 2496.6 3866.9 6243 3864.4 3480.4 5718 2520.9 FALSE TRUE FALSE 2892.66279 3824.579046 1937.437135 2486.269731 3820.789743 4948.131427 3972.824663 4541.557938 5090.749706 2608.501087 1.108936778 1.466197988 0.742739631 0.953141152 1.464745314 1.896925192 1.523029713 1.741060397 1.95159961 1 11.34900532 -5.594448477 4.272409232 1.056318097 1.699867172 0.258900557 0.340596454 0.084054878 2.993777355 0.027017278 0.056244241 2.54E-06 5.594448477 0.643549075 KTETQEKNPLPSK ddPTM_HeLa_Curcumin_4h_R1 2 KTETQEKNPLPSK 13 2 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 0 ; ; 66.708 0.017272 30410000 19691.7 15895.9 17358.7 18038 17564.8 19042.2 16112.8 16297.5 17481 14461.9 FALSE FALSE TRUE 18133.08117 17269.87077 18002.02869 17963.36354 17355.35123 15092.63307 16564.8818 21266.53273 15563.37804 14964.44995 1.211743915 1.154059843 1.202986328 1.200402527 1.159772079 1.008565843 1.106948926 1.421136948 1.040023395 1 13.86925163 -9.32556595 0.924708 0.994172692 1.176709599 0.299508428 0.098759189 0.602590309 0.875551239 0.07711744 0.01798838 4.73E-10 9.32556595 0.182536907 KTETQEKNPLPSKETIEQEK ddPTM_HeLa_Curcumin_4h_R1 2 KTETQEKNPLPSKETIEQEK 20 3 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 0 ; ; 29.118 0.019942 22912500 13520.3 10989.4 12012.1 12335.1 10851.6 14956.2 10781.2 11571.3 14245.1 12605.3 FALSE FALSE TRUE 12450.15399 11939.27477 12457.27899 12284.06062 10722.20176 11854.11553 11083.69146 15099.3361 12682.44817 13043.33324 0.954522419 0.915354576 0.955068675 0.941788453 0.822044608 0.908825629 0.849759126 1.157628639 0.972331837 1 13.67102498 -8.138461172 0.74319006 0.994682572 0.927069498 0.040796642 0.085092509 1.038665997 1.254025264 0.030386222 0.019563782 7.27E-09 8.138461172 -0.067613074 SSRSS(ph)PELTR ddPTM_HeLa_Curcumin_4h_R1 1 SSRSSPELTR 10 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.002)S(0.002)RS(0.223)S(0.772)PELTR 81.278 0.013216 24762000 1414 1185.5 1257.4 1486.5 1123.4 1295.8 744.11 389.83 1676.3 1504.4 TRUE FALSE FALSE 1302.080408 1287.969338 1304.00035 1480.349257 1110.004189 1027.036473 764.9877239 508.6873724 1492.414084 1556.677788 0.836448248 0.827383385 0.837681606 0.950967033 0.713059695 0.659761758 0.491423292 0.326777562 0.958717401 1 10.60425464 -4.40025453 0.573979714 0.923179397 5.82E-19 0.913235439 0.060513049 0.760600178 0.186267881 0.0142446 0.450338881 3.98E-05 4.40025453 -0.923179397 down KTGSPGS(ph)PGAGGVQSTAK ddPTM_HeLa_Curcumin_4h_R1 2 KTGSPGSPGAGGVQSTAK 18 1 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 0 KT(0.003)GSPGS(0.997)PGAGGVQSTAK;KTGS(0.019)PGS(0.981)PGAGGVQSTAK ; 153.34 2.88E-05 114987000 11512.2 9278.5 9978.2 10524.8 10096.8 13442.2 10322.7 4961.8 9669.9 8846.5 TRUE FALSE FALSE 10600.99722 10080.4922 10348.00087 10481.25117 9976.402254 10654.1362 10612.32718 6474.629979 8609.136163 9153.915217 1.158083396 1.101221932 1.130445348 1.145001993 1.089850847 1.16388845 1.159321113 0.707307182 0.940486771 1 13.16017321 -4.255846766 24.85449483 1.097418314 0.707307001 0.735893208 0.070338511 219.5452038 975662.8874 0.009618774 0.112988738 5.55E-05 4.255846766 -0.390111313 KTGSPGS(ph)PGAGGVQSTAKK ddPTM_HeLa_Curcumin_4h_R1 2 KTGSPGSPGAGGVQSTAKK 19 2 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 0 KT(0.25)GS(0.146)PGS(0.603)PGAGGVQS(0.001)T(0.001)AKK;KT(0.002)GS(0.001)PGS(0.998)PGAGGVQSTAKK ; 102.29 0.00023531 31193000 7022 4927.5 4887.6 5753.3 4466.9 7525.9 5302.7 3060.6 7870.1 6360.2 TRUE FALSE FALSE 6466.20129 5353.411143 5068.738756 5729.494369 4413.635135 5964.943506 5451.479491 3993.762851 7006.76972 6581.216477 0.982523719 0.813437935 0.770182651 0.870582876 0.670641233 0.906358806 0.828339185 0.606842651 1.064661791 1 12.68413856 -7.231589178 3.523060653 0.992945069 0.783732635 0.60831835 0.086083944 0.118167168 3.068129566 0.013304868 0.015974144 5.87E-08 7.231589178 -0.209212434 KTLS(ph)GLEVSMVT(ph)AVPGR ddPTM_HeLa_Curcumin_4h_R1 1 KTLSGLEVSMVTAVPGR 17 1 P00390-2;P00390-3;P00390 P00390-2 GSR "Glutathione reductase, mitochondrial" 2 0 KT(0.446)LS(0.554)GLEVS(0.024)MVT(0.976)AVPGR 46.833 0.01921 169490000 2037.8 1725.2 1938.3 1944.8 2050.7 2457.8 1827.9 1290 2397.6 2253.1 TRUE FALSE FALSE 1876.50598 1874.318601 2010.135103 1936.752933 2026.246742 1948.024575 1879.185954 1683.315062 2134.589278 2331.395057 0.804885459 0.803947231 0.862202696 0.830727048 0.869113424 0.835561768 0.806034974 0.722020516 0.915584543 1 11.18697778 -9.284503784 0.702869776 1.019268342 0.817839909 0.572133729 0.04630565 0.360634635 0.272084455 0.044070401 0.008383313 5.19E-10 9.284503784 -0.201428433 KTNTTASAK(ac)VAPVR ddPTM_HeLa_Curcumin_4h_R1 2 KTNTTASAKVAPVR 14 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 0 1 ; KTNTTASAK(1)VAPVR;KTNTTASAK(1)VAPVR 132.65 0.00026036 7580700 2889.9 2129.39 2500.1 2390.95 2514.8 3356.9 2705.2 2161.2 2748.9 2845.9 FALSE TRUE FALSE 2661.161366 2313.444983 2592.755905 2381.056882 2484.812652 2660.6411 2781.100631 2820.139931 2447.352547 2944.794813 0.90368312 0.785604815 0.880453841 0.808564614 0.84379823 0.903506447 0.944412364 0.957669417 0.831077444 1 11.5239514 -8.534074448 0.943334118 0.989350191 0.876210929 0 0.071871526 0.366009066 0.665946127 0.021312423 0.011598156 2.92E-09 8.534074448 -0.113139261 KTPLALAGSPT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 KTPLALAGSPTPK 13 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 0 KTPLALAGS(0.084)PT(0.916)PK 85.636 0.0087223 73535000 8660.1 6694.7 6966 7855.9 7885.4 9913.1 7437.9 4607.8 8582.5 7773.4 TRUE FALSE FALSE 7974.643947 7273.360037 7224.166088 7823.394367 7791.371755 7857.011316 7646.587456 6012.697008 7641.021222 8043.525071 0.991436451 0.90425031 0.898134341 0.972632558 0.968651392 0.976811938 0.950651286 0.747520143 0.949959272 1 12.97361219 -4.251960445 3.272978595 0.977543577 0.712846558 0.732939454 0.036402267 0.136902117 2.297436748 0.005820729 0.092387136 5.60E-05 4.251960445 -0.26469702 KTPQGPPEIY(ph)SDTQFPSLQSTAK ddPTM_HeLa_Curcumin_4h_R1 1 KTPQGPPEIYSDTQFPSLQSTAK 23 1 Q9UKY7-2;Q9UKY7;D6RFH2;D6R9V8;H0Y8K3;Q9UKY7-3;D6RDN0 Q9UKY7-2 CDV3 Protein CDV3 homolog 1 0 KT(0.013)PQGPPEIY(0.904)S(0.075)DT(0.008)QFPSLQSTAK 74.444 0.00095551 16505000 1326.7 1108.2 1108.3 1202.4 1367.2 2062.3 2024.2 745.71 1057.4 921.67 TRUE FALSE FALSE 1221.690295 1203.98787 1149.374573 1197.424787 1350.897033 1634.555733 2080.993604 973.0735462 941.4058655 953.6979639 1.281003359 1.262441481 1.205176708 1.255559761 1.416483084 1.713913414 2.182025844 1.020316267 0.98711112 1 9.897388627 -5.59918823 2.143564062 1.155795795 1.688301286 0.365809259 0.27943339 0.223012318 2.059076758 0.039576776 0.094403327 2.52E-06 5.59918823 0.532505491 KTPSKPPAQLS(ph)PSVPK ddPTM_HeLa_Curcumin_4h_R1 2 KTPSKPPAQLSPSVPK 16 2 F5H8D7;P18887;M0QYS5 F5H8D7 XRCC1 DNA repair protein XRCC1 1 0 KT(0.004)PS(0.004)KPPAQLS(0.864)PS(0.129)VPK;KTPS(0.002)KPPAQLS(0.569)PS(0.428)VPK ; 55.975 0.014179 350310000 20312 14710 17079.7 17955.2 16688.1 20226.7 16094 22217 18935.1 17768.5 TRUE FALSE FALSE 18704.28377 15981.46685 17712.68871 17880.90614 16489.10531 16031.45442 16545.55433 28990.86103 16857.9669 18385.95405 1.017313745 0.869221516 0.963381539 0.972530775 0.896831639 0.871940307 0.899901864 1.576793945 0.91689378 1 14.16631642 -4.257291482 24.99748952 0.971782932 1.576794182 0.906029127 0.061012472 104.8001085 631558.2965 0.009676081 0.099639312 5.53E-05 4.257291482 0.60501125 KTQQLHPVLQKPS(ph)VFGNDSDDDDETSVSESLQR ddPTM_HeLa_Curcumin_4h_R1 1 KTQQLHPVLQKPSVFGNDSDDDDETSVSESLQR 33 2 Q9H0G5 Q9H0G5 NSRP1 Nuclear speckle splicing regulatory protein 1 1 0 KTQQLHPVLQKPS(0.62)VFGNDS(0.368)DDDDET(0.007)S(0.003)VS(0.001)ESLQR 54.241 0.0004008 60346000 1896.6 1416.8 1466.8 1671.7 1552.8 2448.6 1557.1 1647.7 2210.5 1799.6 TRUE FALSE FALSE 1746.482109 1539.261879 1521.160898 1664.782948 1534.283874 1940.732759 1600.788035 2150.076145 1968.01368 1862.135966 0.93789183 0.826610896 0.816890349 0.894017934 0.823937619 1.04220787 0.859651532 1.154628977 1.056858208 1 10.8627427 -4.248841673 24.46006916 0.934594437 1.154629164 0.387445499 0.087086376 1282.831082 2490722.854 0.011890976 0.276958174 5.64E-05 4.248841673 0.220034726 KTQQLHPVLQKPSVFGNDS(ph)DDDDETSVSESLQR ddPTM_HeLa_Curcumin_4h_R1 2 KTQQLHPVLQKPSVFGNDSDDDDETSVSESLQR 33 2 Q9H0G5 Q9H0G5 NSRP1 Nuclear speckle splicing regulatory protein 1 1 0 KTQQLHPVLQKPS(0.086)VFGNDS(0.889)DDDDET(0.009)S(0.012)VS(0.003)ES(0.001)LQR;KT(0.007)QQLHPVLQKPS(0.197)VFGNDS(0.751)DDDDET(0.032)S(0.011)VS(0.002)ESLQR ; 63.657 9.17E-05 181056000 4281 2710.3 3132.7 3377.68 3190.6 4841.6 3336.4 3191.4 4536.8 3204.09 TRUE FALSE FALSE 3942.154333 2944.566255 3248.800618 3363.704055 3152.554179 3837.397584 3430.010405 4164.443169 4039.124391 3315.431889 1.189031916 0.888139571 0.979902687 1.014559842 0.950872853 1.157435204 1.034559152 1.256078637 1.218280009 1 11.6949811 KTS(ph)PASLDFPESQK ddPTM_HeLa_Curcumin_4h_R1 1 KTSPASLDFPESQK 14 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 KT(0.001)S(0.872)PAS(0.127)LDFPESQK 111.66 0.0042832 82053000 3273.9 2274.8 2844 2638.9 2616.9 2846.3 1950.8 1343.1 2979.7 3168.2 TRUE FALSE FALSE 3014.76736 2471.423576 2949.401142 2627.980931 2585.695177 2255.945296 2005.534198 1752.605007 2652.834365 3278.294714 0.919614502 0.75387474 0.89967541 0.80163047 0.788731765 0.68814597 0.61176141 0.53460874 0.809211677 1 11.67872984 -3.669800661 0.242889349 1.010547284 3.40E-17 0.70673291 0.072906715 2.701296056 0.101336957 0.031694259 0.859139544 0.000213894 3.669800661 -1.010547284 KTS(ph)QSEEEEAPR ddPTM_HeLa_Curcumin_4h_R1 2 KTSQSEEEEAPR 12 1 Q7RTP6;A0A5F9ZHV5;J3KSK6;Q7RTP6-2;Q7RTP6-4;Q7RTP6-3;Q7RTP6-5 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 0 KT(0.393)S(0.607)QS(0.001)EEEEAPR;KT(0.201)S(0.794)QS(0.005)EEEEAPR ; 101.72 0.013131 16293500 3282.3 3273.9 3646.8 3392.2 3628.9 4186.6 3712.9 5282.5 4780.3 4394.4 TRUE FALSE FALSE 3022.502492 3556.881328 3781.953616 3378.163975 3585.627738 3318.251967 3817.073981 6893.109932 4255.91305 4547.105073 0.664709182 0.782229852 0.831727782 0.742926306 0.788551766 0.729750449 0.839451458 1.515933725 0.935961008 1 12.15073263 -4.26223526 5.863266372 0.815672528 1.536197234 0.838110242 0.092756299 0.052685797 8.174611657 0.017553754 0.151027343 5.47E-05 4.26223526 0.720524705 KTS(ph)SDDESEEDEDDLLQR ddPTM_HeLa_Curcumin_4h_R1 1 KTSSDDESEEDEDDLLQR 18 1 Q9Y5J1 Q9Y5J1 UTP18 U3 small nucleolar RNA-associated protein 18 homolog 1 0 KT(0.128)S(0.436)S(0.436)DDESEEDEDDLLQR 110.32 0.00034685 8157800 3319.6 2667.3 2571.4 2740 3178.3 3766.2 2134.4 2187.5 3313.7 2789.1 TRUE FALSE FALSE 3056.850157 2897.849527 2666.698346 2728.662606 3140.400848 2985.047666 2194.28552 2854.45868 2950.1954 2886.021017 1.059191925 1.004098553 0.924005172 0.945475653 1.088142058 1.034312518 0.760315156 0.989063719 1.022236284 1 11.49486609 -4.790541182 24.99958924 1.018129986 0.874689317 0.37475681 0.069060267 125.6480754 107936.5899 0.009324204 0.02797916 1.62E-05 4.790541182 -0.143440669 KTSAVS(ph)SPLLDQQR ddPTM_HeLa_Curcumin_4h_R1 1 KTSAVSSPLLDQQR 14 1 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 0 KTS(0.001)AVS(0.5)S(0.5)PLLDQQR 135.14 0.0014553 8754100 2324.1 1811.1 2115.5 2129.6 2357.4 2438.3 1993.7 958.43 2234.9 2114.7 TRUE FALSE FALSE 2140.145033 1967.643414 2193.902291 2120.788279 2329.289545 1932.569095 2049.637856 1250.650895 1989.737061 2188.185668 0.978045448 0.899212276 1.002612495 0.96919942 1.064484417 0.883183325 0.936683704 0.571546973 0.909309064 1 11.09551944 -3.904364631 1.522587359 0.983820193 2.56E-19 0.817025731 0.054690736 0.703568278 0.730883377 0.006555547 1.351827374 0.000124634 3.904364631 -0.983820193 KTSFDQDS(ph)DVDIFPSDFPTEPPSLPR ddPTM_HeLa_Curcumin_4h_R1 2 KTSFDQDSDVDIFPSDFPTEPPSLPR 26 1 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 1 0 KT(0.004)S(0.004)FDQDS(0.991)DVDIFPSDFPTEPPSLPR;KT(0.011)S(0.011)FDQDS(0.979)DVDIFPSDFPTEPPSLPR ; 91.503 5.65E-06 707180000 4492.3 2707.4 4243.6 4954.6 4119.7 4874 3746.1 3263.6 5705.6 4594.3 TRUE FALSE FALSE 4136.729715 2941.415592 4400.871549 4934.099178 4070.575268 3863.077459 3851.205484 4258.656616 5079.709955 4753.951583 0.870166564 0.618730658 0.925729148 1.037894285 0.856250889 0.81260345 0.810106165 0.895814049 1.068523704 1 12.21491149 -8.795310309 0.985239574 0.990060845 0.854670314 0.305350395 0.103645503 0.58037963 1.11732123 0.045112562 0.020370197 1.60E-09 8.795310309 -0.135390531 KTSPAS(ph)LDFPESQK ddPTM_HeLa_Curcumin_4h_R1 1 KTSPASLDFPESQK 14 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 KT(0.018)S(0.456)PAS(0.522)LDFPES(0.004)QK 121.13 0.0026711 77560000 1926.2 1433.5 1701.5 1660.5 1613.2 1833.4 1085.4 766.14 1792.5 1855.1 TRUE FALSE FALSE 1773.739237 1557.405352 1764.559087 1653.629291 1593.963644 1453.132173 1115.853403 999.7325591 1595.867235 1919.564587 0.924032069 0.811332613 0.919249656 0.861460616 0.830377709 0.757011347 0.581305474 0.52081215 0.831369387 1 10.90656339 -3.836832602 0.378174511 0.974111296 1.06E-13 0.811886439 0.061780718 1.493023582 0.11593039 0.013363133 0.70400511 0.000145602 3.836832602 -0.974111296 KTSS(ph)DDES(ph)EEDEDDLLQR ddPTM_HeLa_Curcumin_4h_R1 1 KTSSDDESEEDEDDLLQR 18 1 Q9Y5J1 Q9Y5J1 UTP18 U3 small nucleolar RNA-associated protein 18 homolog 2 0 KT(0.103)S(0.411)S(0.487)DDES(0.999)EEDEDDLLQR 75.3 0.0039655 397550000 3078.8 2436.9 2611.3 2984.4 2456.2 3219.9 2549.5 2506 3144.8 2730.3 TRUE FALSE FALSE 2835.109731 2647.534777 2708.077075 2972.051344 2426.911419 2552.056444 2621.032108 3270.067864 2799.823308 2825.177722 1.003515534 0.937121498 0.958551051 1.051987392 0.859029646 0.903325984 0.927740612 1.157473329 0.991025551 1 11.46412591 -7.29509498 22.53767765 1.001660125 0.964858582 0.020563672 0.078729958 501.357943 335735.6783 0.01291324 0.014767792 5.07E-08 7.29509498 -0.036801544 KTSS(ph)DDESEEDEDDLLQR ddPTM_HeLa_Curcumin_4h_R1 1 KTSSDDESEEDEDDLLQR 18 1 Q9Y5J1 Q9Y5J1 UTP18 U3 small nucleolar RNA-associated protein 18 homolog 1 0 KT(0.06)S(0.235)S(0.705)DDESEEDEDDLLQR 104.18 0.00050432 6112400 1452 1029.4 1197.9 1153.5 1041.6 1201.8 941.12 699.63 1052.2 1014.3 TRUE FALSE FALSE 1337.072668 1118.376749 1242.295228 1148.727123 1029.1796 952.5331329 967.5252943 912.9439663 936.7762925 1049.54685 1.273952343 1.065580588 1.183649142 1.094498186 0.980594245 0.907566092 0.921850506 0.869845845 0.892553098 1 10.03555085 -5.646089726 2.143796982 1.131182092 0.900880408 0.362170982 0.101621375 0.19988933 1.8573858 0.015546199 0.036057708 2.26E-06 5.646089726 -0.230301684 KTTEEQVQAS(ph)TPCPR ddPTM_HeLa_Curcumin_4h_R1 1 KTTEEQVQASTPCPR 15 1 Q14137 Q14137 BOP1 Ribosome biogenesis protein BOP1 1 0 KTTEEQVQAS(0.651)T(0.349)PCPR 113.81 0.00085681 8374000 4784.4 3668.4 3375.6 3631.8 3165.9 5886.7 5590.9 3370.5 4787.3 3378.4 TRUE FALSE FALSE 4405.709692 3985.48015 3500.702705 3616.772574 3128.14871 4665.732063 5747.765607 4398.149934 4262.145167 3495.799149 1.260286848 1.140076984 1.0014027 1.034605371 0.894830789 1.33466823 1.644192175 1.258124322 1.219219122 1 11.77140658 -5.028569748 9.680655154 1.098129429 1.460848387 0.569046246 0.134827671 0.246741115 82.54616516 0.020352588 0.053256986 9.36E-06 5.028569748 0.362718958 KTVEDEDQDS(ph)EEEKDNDSYIK ddPTM_HeLa_Curcumin_4h_R1 2 KTVEDEDQDSEEEKDNDSYIK 21 2 Q9Y5T5-2;Q9Y5T5;Q9Y5T5-4;Q9Y5T5-3 Q9Y5T5-2 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 0 KTVEDEDQDS(0.999)EEEKDNDS(0.001)YIK;KT(0.02)VEDEDQDS(0.957)EEEKDNDS(0.012)Y(0.012)IK ; 77.66 0.0010571 44107000 5953.5 5357.6 5346.2 5096.9 5769 5787.6 5248.8 4272.1 5511.3 4783 TRUE FALSE FALSE 5482.274193 5820.687071 5544.334875 5075.810378 5700.208443 4587.18652 5396.067202 5574.643624 4906.724179 4949.208894 1.107707173 1.176084339 1.120246689 1.025580146 1.151741332 0.926852477 1.090288835 1.126370647 0.991415857 1 12.27298222 -9.27271916 1.082033985 1.001646858 1.089337439 0.239259844 0.066986563 0.639497648 1.378227581 0.04063806 0.011877003 5.34E-10 9.27271916 0.087690581 KTVSLTPSPT(ph)T(ph)QVETPDLVDHDNTSPLFR ddPTM_HeLa_Curcumin_4h_R1 1 KTVSLTPSPTTQVETPDLVDHDNTSPLFR 29 1 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 2 0 KT(0.004)VS(0.029)LT(0.029)PS(0.377)PT(0.718)T(0.718)QVET(0.124)PDLVDHDNT(0.001)S(0.001)PLFR 51.104 0.0045065 5371800 809.07 709.16 578.69 444.25 623.34 420.6 421.79 476.26 879.84 672.81 TRUE FALSE FALSE 745.0312558 770.4566304 600.1367605 442.4118112 615.9070776 333.3628189 433.6242922 621.4694816 783.3237533 696.1900974 1.070154917 1.106675653 0.862030015 0.635475588 0.88468233 0.478838783 0.622853289 0.892672108 1.12515785 1 9.443337483 -6.527387085 3.825997596 1.03907756 0.697663815 0.674122615 0.120816835 0.099220328 3.234239409 0.017977448 0.026740432 2.97E-07 6.527387085 -0.341413745 KTVTPAK(ac)AVTTPGK ddPTM_HeLa_Curcumin_4h_R1 1 KTVTPAKAVTTPGK 14 2 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 K(0.003)TVTPAK(0.997)AVTTPGK 107.5 0.00050575 3851500 3715.7 3236.5 3838.4 3630.4 3783.8 4421.9 4008.5 3295.7 3801.8 3425.7 FALSE TRUE FALSE 3421.598424 3516.248638 3980.654481 3615.378367 3738.680656 3504.748095 4120.967722 4300.543758 3384.752052 3544.74282 0.965259991 0.991961566 1.122974129 1.019926847 1.054711398 0.988717172 1.162557605 1.213217426 0.954865338 1 11.79146524 -1 0.42866315 0.988273406 5.621787698 0.656056012 0.049538226 30.12712628 0.339059994 0.011174898 121.6047384 0.1 1 4.633514292 KTVTPAK(ac)AVTTPGKK ddPTM_HeLa_Curcumin_4h_R1 1 KTVTPAKAVTTPGKK 15 3 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 KTVTPAK(1)AVTTPGKK 103.3 0.00091234 7652000 5277.8 4560.6 4389.3 4770.3 5049.6 5944.6 4767 4306.5 5759.2 4966.3 FALSE TRUE FALSE 4860.056561 4954.797942 4551.971319 4750.561763 4989.386818 4711.622951 4900.74919 5619.532025 5127.430169 5138.878555 0.945742638 0.964178836 0.885790795 0.924435499 0.970909657 0.916858202 0.95366122 1.093532755 0.997772201 1 12.32723784 -4.260052528 24.30385247 0.95888405 1.093532821 0.598834027 0.034454221 50.23540067 880205.7069 0.005341576 0.044673658 5.49E-05 4.260052528 0.134648771 KVAS(ph)PSPSGSVLFTDEGVPK ddPTM_HeLa_Curcumin_4h_R1 2 KVASPSPSGSVLFTDEGVPK 20 1 P56181-2 P56181-2 1 0 KVAS(0.967)PS(0.032)PS(0.001)GSVLFTDEGVPK;KVAS(0.701)PS(0.187)PS(0.085)GS(0.027)VLFTDEGVPK ; 71.418 0.0027706 89976000 6038.7 4663.4 4893.2 6312.3 5652.7 8195.4 5537.1 5628 7076.1 4834.4 TRUE FALSE FALSE 5560.730523 5066.483516 5074.546296 6286.181375 5585.295244 6495.581659 5692.456124 7343.951292 6299.869534 5002.39504 1.111613633 1.012811558 1.014423342 1.256634337 1.116524225 1.298494343 1.137946139 1.468087033 1.259370658 1 12.28840328 -1 0.288207864 1.02924714 3.933517506 0.415182107 0.109735879 21.53085436 0.275071717 0.032614957 32.23666089 0.1 1 2.904270366 KVDAQS(ph)SAGEEDVLLSK ddPTM_HeLa_Curcumin_4h_R1 1 KVDAQSSAGEEDVLLSK 17 1 K7EQL6;Q8NFA0 K7EQL6 USP32 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 32 1 0 KVDAQS(0.561)S(0.439)AGEEDVLLSK 75.646 0.0062343 5190200 1823.3 1426.7 1949.4 1673.3 1855.5 2191.2 1558.8 1181.7 1764.9 1830.6 TRUE FALSE FALSE 1678.983881 1550.017591 2021.646479 1666.376328 1833.374374 1736.72042 1602.535733 1541.99489 1571.294886 1894.213214 0.88637534 0.818290982 1.067275038 0.879719514 0.967881736 0.916855826 0.846016552 0.814055608 0.82952377 1 10.88738302 -13.52287875 0.242712227 1.602702402 0.88861317 0 0.089073882 54.7922663 0.718217209 15.80935209 0.045327666 3.00E-14 13.52287875 -0.714089233 KVDLTLLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 KVDLTLLSPK 10 1 E7EVA0;P27816-4;B5MEG9 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 KVDLT(0.005)LLS(0.995)PK;KVDLT(0.02)LLS(0.98)PK ; 115.24 0.0084915 526540000 10813.1 8632.8 9790.5 10168 8568.5 11820.8 9511 15921.3 9740.2 8697 TRUE FALSE FALSE 9957.231725 9378.980765 10153.34454 10125.92751 8466.326234 9369.032832 9777.853062 20775.63108 8671.724429 8999.220103 1.106454961 1.042199286 1.128247162 1.125200561 0.940784439 1.041093864 1.086522271 2.308603506 0.963608438 1 13.13558426 -4.261355327 6.0158537 1.053603806 2.342213258 0.974468431 0.061220761 0.01365496 2.381201251 0.008315929 0.071572316 5.48E-05 4.261355327 1.288609452 KVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLR ddPTM_HeLa_Curcumin_4h_R1 1 KVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLR 35 2 B1ALC0;O15511;O15511-2 B1ALC0 ARPC5 Actin-related protein 2/3 complex subunit 5 0 0 91.985 3.88E-11 20777000 1775.3 1486.2 1440.4 1699 1489.7 1567.2 1427 1467.2 1664.4 1586 FALSE FALSE TRUE 1634.783132 1614.660506 1493.782491 1691.969988 1471.9363 1242.145054 1467.037779 1914.542526 1481.819484 1641.113382 0.99614271 0.98388114 0.910225038 1.030989088 0.896913228 0.756891673 0.893928351 1.166611976 0.902935471 1 10.6804592 -6.720658915 1.122897668 0.999240472 0.927719012 0 0.104360281 0.903009869 2.277784556 0.018578151 0.028993261 1.90E-07 6.720658915 -0.07152146 KVEAQLQELQVK ddPTM_HeLa_Curcumin_4h_R1 2 KVEAQLQELQVK 12 1 P35579 P35579 MYH9 Myosin-9 0 0 ; ; 134.21 9.16E-05 5513100 7191.6 6083.2 6960.3 7271.5 6637.5 8640.1 6719.1 6428.9 8175.5 7264.9 FALSE FALSE TRUE 6622.377271 6609.004702 7218.254841 7241.41246 6558.352148 6848.045866 6907.619862 8389.042015 7278.668104 7517.354734 0.88094516 0.879166267 0.960212082 0.963292636 0.872428185 0.910964842 0.918889703 1.115956651 0.968248588 1 12.87600937 -4.258775845 24.48886794 0.932632299 1.115956739 0.645512566 0.04161812 115.1647952 1058755.127 0.007277293 0.066738013 5.51E-05 4.258775845 0.18332444 KVEEAEPEEFVVEK ddPTM_HeLa_Curcumin_4h_R1 2 KVEEAEPEEFVVEK 14 1 Q13185;S4R2Y4;C9JMM0;B8ZZ43 Q13185 CBX3 Chromobox protein homolog 3 0 0 ; ; 156.96 0.00019369 18651000 10117.9 7826.1 8793 8460.1 9080.9 10090.3 8484.3 7888.9 10250.6 9380.8 FALSE FALSE TRUE 9317.057539 8502.553212 9118.876315 8425.094348 8972.616198 7997.458039 8722.346624 10294.18929 9126.134826 9706.782102 0.959850282 0.875939433 0.939433503 0.867959563 0.924365676 0.823904148 0.898582716 1.060515131 0.94018128 1 13.24477739 -7.630136354 1.628659919 0.987153119 0.908602546 0.109308273 0.061203687 0.337448546 1.837576485 0.011777734 0.012042094 2.34E-08 7.630136354 -0.078550573 KVEEDLKADEPSS(ph)EES(ph)DLEIDK ddPTM_HeLa_Curcumin_4h_R1 1 KVEEDLKADEPSSEESDLEIDK 22 2 P50502;Q3KNR6;F6VDH7 P50502 ST13 Hsc70-interacting protein 2 0 KVEEDLKADEPS(0.586)S(0.707)EES(0.707)DLEIDK 69.986 0.0018089 46070000 3595 3086.7 3333.4 3678.1 4241.7 3777.6 3228.5 3192.1 3039.6 3235.3 TRUE FALSE FALSE 3310.451957 3353.500594 3456.938736 3662.880997 4191.120498 2994.083178 3319.083021 4165.356595 2706.163485 3347.726434 0.988865734 1.0017248 1.032622828 1.094139879 1.251930401 0.894363156 0.991443921 1.244234461 0.808358609 1 11.70896592 -6.495606815 3.126701919 0.995289136 1.086393244 0.223037984 0.115488957 0.36257903 7.207211333 0.015322628 0.023354699 3.19E-07 6.495606815 0.091104108 KVEEDLKADEPSSEES(ph)DLEIDK ddPTM_HeLa_Curcumin_4h_R1 1 KVEEDLKADEPSSEESDLEIDK 22 2 P50502;Q3KNR6;F6VDH7 P50502 ST13 Hsc70-interacting protein 1 0 KVEEDLKADEPS(0.008)S(0.024)EES(0.968)DLEIDK 112.28 0.0002358 0 1159.8 942.42 890.06 1003.3 1091.9 1016.7 935.51 891.46 1095.8 1060.9 TRUE FALSE FALSE 1068.000606 1023.878585 923.0464066 999.1486104 1078.879806 805.8249594 961.7578928 1163.26205 975.5934816 1097.766196 0.97288531 0.932692762 0.840840618 0.910165219 0.982795617 0.734058821 0.87610449 1.059662845 0.888707892 1 10.1003551 -7.189148814 2.700717617 0.988228082 0.895710261 0.02600348 0.086403955 0.315633172 4.446627804 0.013643913 0.016615567 6.47E-08 7.189148814 -0.092517821 KVEEEGS(ph)PGDPDHEASTQGR ddPTM_HeLa_Curcumin_4h_R1 3 KVEEEGSPGDPDHEASTQGR 20 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 0 KVEEEGS(1)PGDPDHEASTQGR;KVEEEGS(0.907)PGDPDHEAS(0.046)T(0.046)QGR;KVEEEGS(0.964)PGDPDHEAS(0.035)T(0.001)QGR ;; 127.16 3.29E-05 159244000 8951 7565.6 6601 7841.3 8222.1 9842.5 7793.7 4862.6 9760.5 8493.4 TRUE FALSE FALSE 8242.518905 8219.536752 6845.638867 7808.854778 8124.056828 7801.054552 8012.370246 6345.184355 8689.79757 8788.545018 0.937870704 0.935255692 0.778927439 0.888526458 0.924391559 0.887638914 0.911683359 0.721983484 0.988764073 1 13.10140863 -1 0.058795182 1.206255422 0.256934085 0.484485034 0.059145538 200.3239851 0.890238086 3.021748036 16.48016371 0.1 1 -0.949321337 KVEEEQEADEEDVS(ph)EEEAESK ddPTM_HeLa_Curcumin_4h_R1 4 KVEEEQEADEEDVSEEEAESK 21 1 Q9H3N1 Q9H3N1 TMX1 Thioredoxin-related transmembrane protein 1 1 0 KVEEEQEADEEDVS(0.998)EEEAES(0.002)K;KVEEEQEADEEDVS(0.973)EEEAES(0.027)K;KVEEEQEADEEDVS(0.993)EEEAES(0.007)K;KVEEEQEADEEDVS(0.997)EEEAES(0.003)K ;;; 141.21 7.02E-06 125697000 15200.6 15609 18360.1 25687.1 20189.9 22749.7 9712.2 6042.4 26312.6 20170.3 TRUE FALSE FALSE 13997.45647 16958.17241 19040.54146 25580.81359 19949.14863 18031.15578 9984.698193 7884.699944 23426.17361 20871.21642 0.670658393 0.812514808 0.912287098 1.225650344 0.95582108 0.863924527 0.478395604 0.377778649 1.122415346 1 14.34922707 -4.723693687 4.030458244 0.88125919 0.402523284 0.617418385 0.157342808 0.124226239 4.233741038 0.024498393 0.097790377 1.89E-05 4.723693687 -0.478735907 KVEGNFNPFAS(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 2 KVEGNFNPFASPQK 14 1 Q5TH58;Q9H6K1-2;Q9H6K1 Q5TH58 C6orf106 Uncharacterized protein C6orf106 1 0 KVEGNFNPFAS(1)PQK;KVEGNFNPFAS(1)PQK ; 157.37 0.00055765 169148000 5852.4 4407.6 5269.4 5025.4 5053 5754.7 4657.7 2936.46 5885.8 4721.3 TRUE FALSE FALSE 5389.176365 4788.573304 5464.688599 5004.606226 4992.746275 4561.110351 4788.382526 3831.773136 5240.142466 4885.364824 1.103126698 0.980187453 1.118583524 1.024407881 1.021980232 0.933627378 0.980148402 0.784337153 1.072620501 1 12.25425059 -3.267155778 0.698942084 1.048145665 9.50E-21 0.72903752 0.047342304 4.124348745 0.50851992 0.008559161 4.74422163 0.00054056 3.267155778 -1.048145665 KVELS(ph)ESEEDKGGK ddPTM_HeLa_Curcumin_4h_R1 2 KVELSESEEDKGGK 14 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 KVELS(0.998)ES(0.002)EEDKGGK;KVELS(0.998)ES(0.002)EEDKGGK ; 107.65 0.0024031 331120000 12264.9 9701.1 10750.8 11774.5 9805.5 11540.6 9906.1 8186.8 11482 9900.6 TRUE FALSE FALSE 11294.12022 10539.61986 11149.23411 11725.78024 9688.575817 9146.949471 10184.03851 10682.91763 10222.45333 10244.64511 1.102441334 1.028793066 1.088298714 1.144576519 0.94572098 0.892851765 0.99408407 1.042780644 0.997833816 1 13.32258239 -5.728589836 24.99964757 1.057209216 0.965231964 0.393948751 0.055423099 167.3128303 127330.1126 0.008752333 0.017503692 1.87E-06 5.728589836 -0.091977252 KVESLQEEIAFLK ddPTM_HeLa_Curcumin_4h_R1 2 KVESLQEEIAFLK 13 1 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 0 ; ; 162.93 1.01E-05 29628600 6100.3 4274.5 4475.4 5450.4 5296.5 6971.1 5632.8 5484.2 4973.5 4024.64 FALSE FALSE TRUE 5617.454818 4643.968733 4641.262261 5427.847689 5233.342697 5525.21528 5790.841208 7156.307334 4427.919493 4164.49594 1.348891894 1.115133452 1.11448356 1.303362464 1.256656933 1.326742866 1.390526318 1.718409007 1.063254607 1 12.02392617 -1 0.390893083 1.145782865 9.116627957 0.767860937 0.095119413 31.34715656 0.375135397 0.032794458 193.214942 0.1 1 7.970845092 KVESLQEEIAFLKK ddPTM_HeLa_Curcumin_4h_R1 4 KVESLQEEIAFLKK 14 2 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 0 ;;; ;;; 136.01 0.00017878 72893100 10568.7 7713.3 10441.1 10365.2 8539.6 8845.24 7752.9 6763.78 7764.83 5728.66 FALSE FALSE TRUE 9732.176243 8380.003282 10828.05635 10322.31155 8437.770847 7010.637518 7970.425508 8826.025385 6913.047576 5927.730509 1.641804773 1.413695051 1.826678243 1.741359789 1.42344036 1.182684926 1.344599842 1.488938367 1.166221637 1 12.53326414 -9.351492427 1.023447261 0.993765069 1.513164358 0.447347697 0.185908149 0.37717932 0.693482734 0.144453929 0.035917942 4.45E-10 9.351492427 0.519399289 KVGDDIAK ddPTM_HeLa_Curcumin_4h_R1 2 KVGDDIAK 8 1 P30050 P30050 RPL12 60S ribosomal protein L12 0 0 ; ; 99.653 0.003939 15987200 12507 14949.6 11316 9506.7 9894.5 14007.8 10768.3 10227.3 11131.3 13542.5 FALSE FALSE TRUE 11517.05775 16241.77681 11735.38091 9467.363794 9776.51455 11102.42438 11070.42952 13345.55669 9910.224239 14013.10087 0.821877889 1.159042311 0.837457821 0.675608053 0.697669605 0.792288908 0.790005697 0.952362851 0.707211368 1 13.77448862 -6.530847764 24.99939797 0.934938786 0.775841752 0.205027061 0.129184518 177.2343562 555995.4164 0.018331465 0.025951106 2.95E-07 6.530847764 -0.159097034 KVIQYLAYVASSHK ddPTM_HeLa_Curcumin_4h_R1 1 KVIQYLAYVASSHK 14 1 P35579;P35579-2;Q5BKV1 P35579 MYH9 Myosin-9 0 0 40.025 0.017125 467990 369.93 420.68 839.34 362.16 497.08 1787.5 858.98 624.36 727.61 862.57 FALSE FALSE TRUE 340.6496502 457.0417047 870.4466788 360.6614779 491.1526457 1416.752351 883.080667 814.7244898 647.7930034 892.5442433 0.38166136 0.512066162 0.975242051 0.404082465 0.550283809 1.587318905 0.989397079 0.912811321 0.725782512 1 9.801779875 -5.290052837 24.78146872 0.674736884 1.145798086 0.448665772 0.259516374 537.2603037 465308.2234 0.043961705 0.098318641 5.13E-06 5.290052837 0.471061202 KVLGVTSEELER ddPTM_HeLa_Curcumin_4h_R1 1 KVLGVTSEELER 12 1 Q8IWB4;Q5VYP0;Q5VU36 Q8IWB4 SPATA31A7;SPATA31A3;SPATA31A5 Spermatogenesis-associated protein 31A7;Spermatogenesis-associated protein 31A3;Spermatogenesis-associated protein 31A5 0 0 40.616 0.016657 6590400 5512.7 7040.3 5515.6 5488.7 7476.4 8168.4 9299.6 8687.9 12431 5876.6 FALSE FALSE TRUE 5076.363978 7648.832161 5720.012988 5465.989214 7387.248813 6474.181763 9560.521747 11336.80072 11067.3504 6080.811413 0.834816875 1.257863736 0.940666072 0.898891421 1.2148459 1.064690437 1.572244409 1.864356571 1.820044999 1 12.57004813 -4.09171792 0.787764779 0.945292499 2.695420534 0.27498323 0.306485908 0.871018726 0.324426028 0.021608132 1.417899829 8.10E-05 4.09171792 1.750128035 KVPCVGLSIGVER ddPTM_HeLa_Curcumin_4h_R1 1 KVPCVGLSIGVER 13 1 B4E1C5;B4DDD8;B3KWE1;P12081-3;P12081-2;P12081-4;P12081;E7ETE2 B4E1C5 HARS "Histidine--tRNA ligase, cytoplasmic" 0 0 39.219 0.017362 2461700 2163.6 2777.1 2298.7 1863.9 2043.5 3082.1 1929.1 1625.7 2235.9 2880 FALSE FALSE TRUE 1992.348777 3017.140149 2383.891844 1856.187676 2019.132597 2442.837718 1983.225354 2121.368446 1990.627364 2980.079786 0.668555515 1.012436031 0.799942289 0.622865094 0.677543134 0.819722254 0.665494046 0.711849547 0.667977875 1 11.54113524 -6.512836631 24.55483571 0.854373465 0.703899438 0.234941996 0.117335762 458.3383098 1120722.936 0.021310266 0.031221733 3.07E-07 6.512836631 -0.150474027 KVPEVTEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 KVPEVTEKK 9 2 C9JQV0;Q9BRJ6 C9JQV0 C7orf50 Uncharacterized protein C7orf50 0 1 KVPEVTEK(1)K 89.805 0.0079677 0 5400.8 6217.7 5733.8 5191.2 4742.4 7242.6 5785.3 6241.1 6309.7 5320.2 FALSE TRUE FALSE 4973.320981 6755.130282 5946.299672 5169.72019 4685.849977 5740.403119 5947.619948 8143.98266 5617.541696 5505.076554 0.903406325 1.227072906 1.080148407 0.939082343 0.851187069 1.042747192 1.080388236 1.479358657 1.020429351 1 12.42654691 -4.152975807 1.857631826 0.977501056 1.741853073 0.653382538 0.100733257 0.5311002 1.478165445 0.015155355 0.768202334 7.03E-05 4.152975807 0.764352017 KVQVAALQAS(ph)PPLDQDDR ddPTM_HeLa_Curcumin_4h_R1 4 KVQVAALQASPPLDQDDR 18 1 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;A0A3B3IRI3;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISZ5;Q9UDY2-5;A0A3B3IRV6;A0A3B3ISF1;A0A3B3IU26;B1AN86;U3KQJ2 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR;KVQVAALQAS(1)PPLDQDDR ;;; 173.34 8.56E-06 464814400 10455.3 9539.1 10231.8 10162 12201.8 12278.6 10195.2 10057.7 11140.4 9947.5 TRUE FALSE FALSE 9627.751973 10363.6173 10610.99951 10119.95234 12056.3015 9731.879952 10481.24987 13124.24643 9918.325992 10293.17488 0.935352997 1.006843604 1.03087722 0.983171126 1.171290845 0.945469212 1.018271815 1.275043568 0.963582772 1 13.32940042 -4.266518113 4.132023218 0.989755023 1.297450978 0.609108084 0.06382149 0.108131117 4.03357983 0.009094069 0.097756235 5.41E-05 4.266518113 0.307695955 KVS(ph)GTLDTPEKTVDSQGPTPVCTPTFLER ddPTM_HeLa_Curcumin_4h_R1 1 KVSGTLDTPEKTVDSQGPTPVCTPTFLER 29 2 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 0 KVS(0.34)GT(0.34)LDT(0.268)PEKT(0.043)VDS(0.008)QGPTPVCTPTFLER 50.229 0.0043337 55884000 1399.9 1153.4 1037.7 1298 641.52 1442 805.76 366.44 1183.6 1176.4 TRUE FALSE FALSE 1289.096438 1253.094757 1076.158075 1292.62922 633.870293 1142.912945 828.367457 478.1658691 1053.762041 1217.279812 1.058997631 1.029422113 0.884067955 1.061899825 0.520726859 0.938907336 0.680507019 0.392815082 0.865669528 1 10.24944512 -4.12671994 0.470287475 1.033000778 6.70E-14 0.566603424 0.146956661 2.181176179 0.295785296 0.028424859 1.281523688 7.47E-05 4.12671994 -1.033000778 KVS(ph)VSESNVLLDEEVLTDPK ddPTM_HeLa_Curcumin_4h_R1 1 KVSVSESNVLLDEEVLTDPK 20 1 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 0 KVS(0.717)VS(0.261)ES(0.023)NVLLDEEVLTDPK 108.13 0.00013446 11601000 9558.4 8823.4 8960.5 9207.5 10151 9321.2 9669.3 10262 8924.8 9607.2 TRUE FALSE FALSE 8801.842554 9586.05538 9292.584012 9169.401805 10029.95595 7387.878048 9940.594534 13390.83656 7945.771769 9941.049485 0.885403756 0.964290078 0.934768912 0.922377644 1.008943369 0.743168823 0.999954235 1.347024434 0.799289027 1 13.27918245 -4.28482768 4.161378562 0.935560759 1.3723207 0.70580265 0.083299553 0.074673147 2.778490732 0.009988292 0.092504505 5.19E-05 4.28482768 0.436759941 KVSGTLDT(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 2 KVSGTLDTPEK 11 1 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 0 KVS(0.001)GT(0.046)LDT(0.953)PEK;KVS(0.208)GT(0.006)LDT(0.786)PEK ; 100.11 0.0039375 49736000 4016.2 4250 4239.3 4413 5023.9 5223 3575.57 2092.14 4818 3967.1 TRUE FALSE FALSE 3698.313532 4617.351062 4396.412187 4394.740175 4963.993274 4139.690925 3675.890871 2730.023855 4289.477454 4104.95643 0.900938559 1.124823403 1.071000938 1.070593623 1.2092682 1.008461599 0.895476221 0.665055501 1.044950788 1 12.00315119 -4.342560425 2.532286012 1.00215952 0.624326914 0.609064104 0.089392661 0.278494506 2.514013393 0.015110441 0.206600119 4.54E-05 4.342560425 -0.377832607 TRPWLQELSMGS(ph)PGPVTNK ddPTM_HeLa_Curcumin_4h_R1 2 TRPWLQELSMGSPGPVTNK 19 1 A0A1B0GV70;Q96N21-2;Q96N21 A0A1B0GV70 ENTHD2 AP-4 complex accessory subunit tepsin 1 0 TRPWLQELSMGS(1)PGPVTNK;TRPWLQELSMGS(1)PGPVTNK ; 102.29 0.000354 61407000 4910.2 4300.7 4737.5 4559.8 4511.2 5510.7 2905.9 1002.39 4851 4485.2 TRUE FALSE FALSE 4521.552489 4672.433344 4913.075918 4540.932756 4457.406886 4367.718702 2987.431733 1308.014097 4318.857437 4641.060366 0.974249877 1.006759873 1.058610647 0.978425704 0.960428552 0.941103618 0.643695944 0.281835183 0.930575579 1 12.18023875 -4.398324972 1.570976742 0.993648216 0.119068622 0.978729193 0.032848601 0.063516673 0.178088313 0.003999654 0.078170383 4.00E-05 4.398324972 -0.874579595 down GPLS(ph)PFNSR ddPTM_HeLa_Curcumin_4h_R1 1 GPLSPFNSR 9 0 A1L390-3;A1L390;A0A0U1RR71;G3V3I3;G3V278 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 0 GPLS(0.621)PFNS(0.379)R 91.701 0.017996 18682000 3367.1 2558.5 3375.5 3237.9 2824.6 3286.7 2170.5 1240.4 3130.1 3182.2 TRUE FALSE FALSE 3100.590482 2779.64534 3500.598999 3224.502428 2790.91849 2605.001371 2231.398388 1618.59225 2786.735861 3292.781213 0.941632705 0.844163386 1.063113147 0.979264099 0.847586982 0.79112495 0.677663727 0.491557788 0.84631674 1 11.68509094 -4.3973779 0.782486899 0.970911089 0.271162822 0.814509274 0.068733603 0.509312716 0.251117952 0.009528703 0.296706764 4.01E-05 4.3973779 -0.699748267 down KVSVS(ph)ESNVLLDEEVLTDPK ddPTM_HeLa_Curcumin_4h_R1 1 KVSVSESNVLLDEEVLTDPK 20 1 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 0 KVS(0.405)VS(0.57)ES(0.025)NVLLDEEVLTDPK 93.633 0.00043456 12150000 5569.1 5034.3 5727.8 4953.6 5702.3 6120.6 5659.3 5956.8 5376.2 6702.7 TRUE FALSE FALSE 5128.299859 5469.44246 5940.077307 4933.103316 5634.303797 4851.118567 5818.084727 7773.000898 4786.444311 6935.618326 0.739414947 0.788601997 0.856459659 0.711270875 0.81237224 0.699450047 0.838870372 1.120736542 0.690125103 1 12.75980879 -9.429953447 1.141760156 1.000733365 0.807010137 0 0.147641146 0.506402855 1.173659783 0.077998106 0.019278643 3.72E-10 9.429953447 -0.193723229 KVTAEADSSS(ph)PTGILATSESK ddPTM_HeLa_Curcumin_4h_R1 3 KVTAEADSSSPTGILATSESK 21 1 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 0 KVT(0.001)AEADS(0.041)S(0.104)S(0.79)PT(0.064)GILAT(0.001)SESK;KVTAEADS(0.012)S(0.337)S(0.524)PT(0.127)GILATSESK;KVT(0.001)AEADS(0.062)S(0.431)S(0.484)PT(0.023)GILATSESK ;; 80.355 0.00054524 78238000 11821.2 9713.8 9186 10814.1 10122.1 14732 12107.6 12450.6 11478.5 9947.3 TRUE FALSE FALSE 10885.53955 10553.41759 9526.441241 10769.35412 10001.40057 11676.41714 12447.30667 16246.73062 10219.33727 10292.96793 1.057570529 1.02530365 0.92552909 1.046282684 0.971673149 1.13440722 1.209301996 1.578430121 0.992846508 1 13.32937142 -4.0206251 1.17564905 1.018190671 2.105354653 0.940495324 0.04365955 0.414779211 0.324960993 0.006572626 0.629417004 9.54E-05 4.0206251 1.087163982 KVTAEADSSSPT(ph)GILATSESK ddPTM_HeLa_Curcumin_4h_R1 1 KVTAEADSSSPTGILATSESK 21 1 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 0 KVTAEADSS(0.016)S(0.011)PT(0.972)GILATSESK 107.33 2.90E-05 36570000 3167.1 2875.8 3145.8 3373 3539 4434.3 3910.6 3851 3755.7 3527.2 TRUE FALSE FALSE 2916.420693 3124.371338 3262.386115 3359.04342 3496.799736 3514.576195 4020.320911 5025.152172 3343.709106 3649.769937 0.799069734 0.856046105 0.893860756 0.920343878 0.958087714 0.962958284 1.101527214 1.376840803 0.916142432 1 11.83358981 -3.767884497 0.929414877 0.899402222 2.170122965 0.897925522 0.049138928 1.495780538 0.519385648 0.011794001 2.388013067 0.000170654 3.767884497 1.270720743 KVTGTEGSSSTLVDYTSTS(ph)STGGSPVR ddPTM_HeLa_Curcumin_4h_R1 1 KVTGTEGSSSTLVDYTSTSSTGGSPVR 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 0 KVTGTEGSSSTLVDY(0.004)T(0.157)S(0.026)T(0.067)S(0.187)S(0.187)T(0.187)GGS(0.187)PVR 114.88 4.17E-07 0 2732.7 2388 2219.5 2516.7 2265.4 2559.5 1873 1396.8 2614.9 2372.2 TRUE FALSE FALSE 2516.403911 2594.408079 2301.756622 2506.286562 2238.386585 2028.630848 1925.551339 1822.67789 2328.052012 2454.633773 1.025164706 1.056943039 0.937718957 1.021042972 0.911902463 0.826449497 0.784455653 0.742545756 0.948431508 1 11.26129208 -5.270678663 1.168031344 1.013038307 0.743904134 0.876556439 0.036160562 0.098015911 0.235165498 0.004430799 0.020385279 5.36E-06 5.270678663 -0.269134173 KVTGTEGSSSTLVDYTSTSSTGGS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 1 KVTGTEGSSSTLVDYTSTSSTGGSPVR 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 0 KVTGTEGSSST(0.001)LVDY(0.002)T(0.157)S(0.019)T(0.047)S(0.116)S(0.116)T(0.116)GGS(0.426)PVR 148.12 7.86E-09 8594100 2522.1 2142.8 1990.2 2406.5 2112.6 2805.4 2043.1 1814.9 2219.4 2305 TRUE FALSE FALSE 2322.473124 2328.014084 2063.958563 2396.542541 2087.408625 2223.528417 2100.423887 2368.254655 1975.937373 2385.098578 0.973743033 0.976066191 0.865355663 1.004798109 0.875187568 0.932258497 0.880644476 0.99293785 0.828451029 1 11.21983318 -6.972578948 24.66400299 0.986932659 0.924494014 0 0.066712813 152.1274791 136831.3798 0.006391677 0.008400187 1.07E-07 6.972578948 -0.062438645 GSEEDPLLS(ph)PVETWK ddPTM_HeLa_Curcumin_4h_R1 2 GSEEDPLLSPVETWK 15 0 Q13017-2;Q13017;H0YK04;A0A0A0MSK6 Q13017-2 ARHGAP5 Rho GTPase-activating protein 5 1 0 GSEEDPLLS(0.999)PVETWK;GSEEDPLLS(0.987)PVET(0.013)WK ; 106.76 0.0025722 12171500 4967.2 3671.2 4687.8 4557.7 4616.8 5558.9 5026.1 8264.7 4978.8 4341 TRUE FALSE FALSE 4574.040879 3988.522169 4861.533992 4538.841445 4561.747675 4405.921478 5167.118839 10784.56898 4432.638096 4491.849427 1.018297909 0.887946543 1.082301193 1.010461619 1.015561129 0.980870252 1.150332157 2.400919523 0.986818051 1 12.13309385 -4.25793302 3.61199982 1.005461897 2.564756759 0.987991818 0.046109956 0.01892455 0.441002043 0.005925674 0.079752094 5.52E-05 4.25793302 1.559294862 up KVTPIDSPPVWS(ph)PEGYMALQSK ddPTM_HeLa_Curcumin_4h_R1 1 KVTPIDSPPVWSPEGYMALQSK 22 1 Q5JSZ5;Q5JSZ5-5 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 KVTPIDSPPVWS(0.988)PEGY(0.012)MALQSK 106.38 1.91E-05 20094000 2130.3 1198.6 1523.2 1787.3 1531.9 1919.2 1380.3 987.43 2156.1 1524.6 TRUE FALSE FALSE 1961.684507 1302.201643 1579.651132 1779.904626 1513.633093 1521.136286 1419.027503 1288.492861 1919.581224 1577.579737 1.243477247 0.825442678 1.001313021 1.128250183 0.959465349 0.964221491 0.899496533 0.816752923 1.216788717 1 10.62349721 -4.491582458 0.501565969 1.096456057 0.67695691 0.370373496 0.112075358 3.074296347 0.599562462 0.027576437 0.723197665 3.22E-05 4.491582458 -0.419499147 KVTSPSSSSSSSS(ph)SDS(ph)ESDDEADVSEVTPR ddPTM_HeLa_Curcumin_4h_R1 1 KVTSPSSSSSSSSSDSESDDEADVSEVTPR 30 1 P56181-2 P56181-2 2 0 KVTSPSSSSS(0.001)S(0.011)S(0.113)S(0.438)S(0.438)DS(0.493)ES(0.495)DDEADVS(0.011)EVTPR 80.009 2.57E-06 8300800 646.09 516.33 580.36 450.25 477.05 783.28 533.23 587.35 661.11 390.38 TRUE FALSE FALSE 594.9512947 560.9592645 601.8686521 448.3869848 471.3614903 620.8188986 548.1909987 766.4303112 588.587887 403.9456759 1.472849767 1.388699763 1.489974242 1.110018033 1.166893269 1.5368871 1.357090894 1.89735986 1.45709664 1 8.658017477 -11.63151251 0.298656469 1.84E-12 1.453378188 0 0.249663727 12.89269332 0.47112664 7.9285234 0.092073088 2.34E-12 11.63151251 1.453378188 KVTSPSSSSSSSS(ph)SDSESDDEADVSEVTPR ddPTM_HeLa_Curcumin_4h_R1 1 KVTSPSSSSSSSSSDSESDDEADVSEVTPR 30 1 P56181-2 P56181-2 1 0 KVTSPSSSSS(0.004)S(0.011)S(0.18)S(0.285)S(0.285)DS(0.191)ES(0.044)DDEADVSEVTPR 122.82 8.11E-13 30811000 6150.3 5194.8 5027.5 5696 5333.4 6635.8 4954.8 1697.7 6312.6 6889.2 TRUE FALSE FALSE 5663.497265 5643.815364 5213.823573 5672.431461 5269.802688 5259.460279 5093.818353 2215.320915 5620.123573 7128.599187 0.794475481 0.791714503 0.731395248 0.79572877 0.739247999 0.737797166 0.714560914 0.310765251 0.788391018 1 12.79940289 -3.62482183 0.151030701 1.050880977 2.19E-20 0.533118522 0.110948845 13.51909626 0.282360828 0.271135048 2.851469335 0.000237235 3.62482183 -1.050880977 KVTSPSSSSSSSSSDSES(ph)DDEADVSEVTPR ddPTM_HeLa_Curcumin_4h_R1 1 KVTSPSSSSSSSSSDSESDDEADVSEVTPR 30 1 P56181-2 P56181-2 1 0 KVTSPSSSSSSSS(0.001)S(0.015)DS(0.019)ES(0.964)DDEADVS(0.001)EVTPR 90.93 5.20E-08 15737000 1305 1240.7 1517.4 1224 1508.8 2189.5 1553.8 1067.1 1766.1 1257.8 TRUE FALSE FALSE 1201.707873 1347.94058 1573.636179 1218.935412 1490.808545 1735.373019 1597.395446 1392.453878 1572.363249 1301.508456 0.923319297 1.035675622 1.209086404 0.936555891 1.145446684 1.333355162 1.227341581 1.069876935 1.208108361 1 10.34596897 -6.247346169 0.821518214 0.9654904 1.206361736 0.050424857 0.126496323 0.403535821 0.535870631 0.019949579 0.046974748 5.66E-07 6.247346169 0.240871336 KVVDYSQFQES(ph)DDADEDYGR ddPTM_HeLa_Curcumin_4h_R1 14 KVVDYSQFQESDDADEDYGR 20 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDY(0.003)S(0.01)QFQES(0.986)DDADEDY(0.001)GR;KVVDYSQFQES(1)DDADEDYGR;KVVDY(0.001)S(0.001)QFQES(0.989)DDADEDY(0.01)GR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDYSQFQES(1)DDADEDYGR;KVVDY(0.001)S(0.006)QFQES(0.993)DDADEDYGR;KVVDYSQFQES(0.997)DDADEDY(0.003)GR ;;;;;;;;;;;;; 114.75 7.19E-05 4849486300 44811.8 43013.9 42647.2 43944.7 46087.4 49806.2 44280.26 42011.44 44490.8 42234.7 TRUE FALSE FALSE 41264.89874 46731.82985 44227.74275 43762.86848 45537.83786 39475.83269 45522.64492 54820.53466 39610.27055 43702.35268 0.944226025 1.069320688 1.012022009 1.001384726 1.041999688 0.903288502 1.041652042 1.254406944 0.906364718 1 15.41542333 -4.298642749 3.49644201 0.985468359 1.276990894 0.709873217 0.051482322 0.094422904 1.994165922 0.006404652 0.068125636 5.03E-05 4.298642749 0.291522535 KVVDYSQFQES(ph)DDADEDYGRDSGPPTK ddPTM_HeLa_Curcumin_4h_R1 1 KVVDYSQFQESDDADEDYGRDSGPPTK 27 2 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 KVVDYSQFQES(0.997)DDADEDY(0.002)GRDS(0.001)GPPTK 72.082 9.92E-05 648690000 4638.7 4430.9 4400.8 4796 3667.6 3901.9 3495.8 4158.1 5689.3 5769.5 TRUE FALSE FALSE 4271.542 4813.887252 4563.897519 4776.155423 3623.866265 3092.601957 3593.88274 5425.885548 5065.198024 5969.989696 0.715502408 0.806347665 0.764473266 0.800027415 0.607013823 0.518024672 0.601991448 0.90886012 0.848443344 1 12.54351273 -10.61693767 0.260602442 1.363351088 0.660690664 0.307889801 0.11770274 6.550922105 0.323089453 1.512805979 0.074283333 2.42E-11 10.61693767 -0.702660424 KVVEAVNS(ph)DS(ph)DSEFGIPKK ddPTM_HeLa_Curcumin_4h_R1 1 KVVEAVNSDSDSEFGIPKK 19 2 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 2 0 KVVEAVNS(0.94)DS(0.636)DS(0.424)EFGIPKK 60.949 0.015607 19526000 3496.3 1586.4 2611.6 3810.9 2679 2967.2 2480.3 2213.3 3421.2 2876.2 TRUE FALSE FALSE 3219.564166 1723.521347 2708.388193 3795.131506 2647.054675 2351.769273 2549.890543 2888.124981 3045.902919 2976.147736 1.081789095 0.579111489 0.910031502 1.275182498 0.889423143 0.790205824 0.856775526 0.97042393 1.023438078 1 11.53923043 KVVEAVNS(ph)DSDS(ph)EFGIPK ddPTM_HeLa_Curcumin_4h_R1 1 KVVEAVNSDSDSEFGIPK 18 1 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 2 0 KVVEAVNS(0.72)DS(0.337)DS(0.943)EFGIPK 50.966 0.019386 49912000 2130.2 1553.9 2151.9 2388.1 2211.3 2397.7 1868.4 1404.8 2410.1 2225.9 TRUE FALSE FALSE 1961.592422 1688.212192 2231.651307 2378.218675 2184.931692 1900.389992 1920.822275 1833.117053 2145.71806 2303.249859 0.851662886 0.732969628 0.968914118 1.032549146 0.948629903 0.82509068 0.833961747 0.795882846 0.931604555 1 11.16945521 -9.28032043 1.03935889 0.999122053 0.876275369 0.13735224 0.086187702 0.666292775 1.304373574 0.058788463 0.01637433 5.24E-10 9.28032043 -0.122846684 KVVEAVNSDS(ph)DS(ph)EFGIPK ddPTM_HeLa_Curcumin_4h_R1 1 KVVEAVNSDSDSEFGIPK 18 1 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 2 0 KVVEAVNS(0.542)DS(0.749)DS(0.709)EFGIPK 52.509 0.01774 43661000 2721.4 1211.1 2359.2 2631.9 2152.2 2682 1705.7 1121 2543.9 2082.2 TRUE FALSE FALSE 2505.998318 1315.782087 2446.634027 2621.009895 2126.536421 2125.722968 1753.557351 1462.78774 2264.840535 2154.556295 1.16311573 0.610697474 1.135562822 1.216496362 0.98699506 0.98661751 0.813883283 0.678927602 1.05118652 1 11.07317508 -4.614549403 1.582577508 1.053064637 0.647153571 0.332469543 0.157454137 0.469327192 1.736439701 0.023291173 0.238621723 2.43E-05 4.614549403 -0.405911066 KVVGCSCVVVK ddPTM_HeLa_Curcumin_4h_R1 2 KVVGCSCVVVK 11 1 P25398 P25398 RPS12 40S ribosomal protein S12 0 0 ; ; 144.57 5.42E-06 13298200 12541.5 7824.5 9811.9 9015.9 10664.3 14326.7 9541.2 10563.5 11708.5 10596.1 FALSE FALSE TRUE 11548.82704 8500.814915 10175.53765 8978.594595 10537.13519 11355.18092 9808.900393 13784.26252 10424.10684 10964.31369 1.053310528 0.775316646 0.928059698 0.818892532 0.961039194 1.035649038 0.894620555 1.257193374 0.950730446 1 13.42052789 -4.25024122 24.15148766 0.978654661 1.257193638 0.467756055 0.093198405 824.1780928 1777480.835 0.014210052 0.280985024 5.62E-05 4.25024122 0.278538977 KVYEDSGIPLPAES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 KVYEDSGIPLPAESPK 16 1 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 0 KVYEDS(0.001)GIPLPAES(0.999)PK;KVYEDSGIPLPAES(1)PK;KVYEDSGIPLPAES(1)PK ;; 105.57 0.00092003 157274800 12040.9 11124.4 13565.6 14079.8 14323.4 13785.6 13925.7 9856.6 13365.7 11699.6 TRUE FALSE FALSE 11087.85006 12085.94357 14068.35307 14021.54152 14152.60281 10926.31116 14316.41766 12861.83197 11899.51615 12106.16023 0.915884959 0.998330052 1.16208218 1.158215425 1.169041425 0.90254143 1.182572954 1.062420431 0.982930667 1 13.56345373 -6.913983232 5.696120168 0.960114304 1.105085292 0.400814381 0.079491053 0.149382239 7.796529497 0.012900574 0.01702051 1.22E-07 6.913983232 0.144970988 KWDGS(ph)EEDEDNSK ddPTM_HeLa_Curcumin_4h_R1 2 KWDGSEEDEDNSK 13 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 0 KWDGS(1)EEDEDNSK;KWDGS(0.942)EEDEDNS(0.058)K ; 88.427 0.0065468 334940000 8485.7 7040.4 8075 7753.3 8622.1 8762.7 7783.8 6260 8823.6 8172.2 TRUE FALSE FALSE 7814.047891 7648.940805 8374.266603 7721.218899 8519.287089 6945.217244 8002.192479 8168.645183 7855.673156 8456.183342 0.924063206 0.904538194 0.9903128 0.91308556 1.007462438 0.821318196 0.946312557 0.965996698 0.928985671 1 13.04579094 -9.270477821 0.850064974 1.002924804 0.932902969 0 0.053474342 0.821924499 0.996710725 0.038158005 0.008851298 5.36E-10 9.270477821 -0.070021835 KWDGS(ph)EEDEDNSKK ddPTM_HeLa_Curcumin_4h_R1 1 KWDGSEEDEDNSKK 14 2 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 0 KWDGS(0.999)EEDEDNS(0.001)KK 111.09 0.0020256 159630000 4631.8 3509 4351.3 4055.4 3724.7 4101.2 3852.9 3554.8 4175.7 3927.1 TRUE FALSE FALSE 4265.188143 3812.302324 4512.563006 4038.619829 3680.285385 3250.56489 3961.002004 4638.642156 3717.636157 4063.566433 1.049616935 0.938166605 1.110493228 0.993860909 0.905678656 0.799929063 0.974759997 1.141519951 0.914870279 1 11.98853076 -5.990062509 20.68520654 1.023513139 0.946243021 0.027631129 0.094808572 39.80291571 82844.01866 0.012943623 0.023420165 1.02E-06 5.990062509 -0.077270118 KWPQGAVPQLPPSAPAT(ph)SEMTTTPERPR ddPTM_HeLa_Curcumin_4h_R1 1 KWPQGAVPQLPPSAPATSEMTTTPERPR 28 2 P27708;F8VPD4;H7BZB3 P27708 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 0 KWPQGAVPQLPPS(0.005)APAT(0.199)S(0.199)EMT(0.199)T(0.199)T(0.199)PERPR 66.613 0.00016606 63524000 3610.8 3088.9 3451.7 3474.9 3207.7 3774.1 2556 1383.4 3755.2 3160.3 TRUE FALSE FALSE 3325.00137 3355.890752 3579.623038 3460.521785 3169.450273 2991.309117 2627.714481 1805.192292 3343.263955 3270.12019 1.016782619 1.026228566 1.09464571 1.058224647 0.969215224 0.914739809 0.803552875 0.552026282 1.022367302 1 11.67512795 -4.19534178 1.056517088 1.019179877 0.269086268 0.957812718 0.031278616 0.314740804 0.251058476 0.005447135 0.273062361 6.38E-05 4.19534178 -0.750093608 KWREAGMKVY(ph)IY(ph)S(ph)S(ph)GS(ph)VEAQK ddPTM_HeLa_Curcumin_4h_R1 1 KWREAGMKVYIYSSGSVEAQK 21 3 A0A0C4DGY8;D6RA00;Q9UHY7 A0A0C4DGY8 ENOPH1 Enolase-phosphatase E1 5 0 KWREAGMKVY(1)IY(1)S(1)S(1)GS(1)VEAQK 40.047 0.0090203 0 193.04 207.58 103.03 171.47 182.49 191.78 152.25 188.08 131.69 168.43 TRUE FALSE FALSE 177.7606803 225.5222902 106.8483824 170.7605026 180.3139259 152.0026662 156.5217252 245.4247262 117.2439365 174.28293 1.019954624 1.294001026 0.613074284 0.979789028 1.034604628 0.872160379 0.89808982 1.408197155 0.672721858 1 7.445287462 -4.253780018 24.34849024 0.987132834 1.408197451 0.330657382 0.189113677 498.0932021 1583342.559 0.020627616 0.287836131 5.57E-05 4.253780018 0.421064617 KWRS(ph)CS(ph)QLLLY(ph)ELQS(ph)AVS(ph)EENK ddPTM_HeLa_Curcumin_4h_R1 1 KWRSCSQLLLYELQSAVSEENK 22 2 Q86XK3-3;Q86XK3;Q86XK3-2 Q86XK3-3 SFR1 Swi5-dependent recombination DNA repair protein 1 homolog 5 0 KWRS(1)CS(1)QLLLY(1)ELQS(1)AVS(1)EENK 43.696 0.008324 0 343.3 289.68 308.52 258.13 483.19 524.41 222.95 306.74 583.81 303.1 TRUE FALSE FALSE 316.1274428 314.7186484 319.9540226 257.0619265 477.4282748 415.6414547 229.205377 400.2636139 519.7675036 313.6327024 1.007954337 1.003462477 1.020155169 0.819627304 1.522252849 1.325249094 0.730808284 1.276217725 1.657249067 1 8.292932187 -5.802993499 24.99996362 0.993677805 1.187120408 0 0.286219175 180.0027547 108293.5234 0.027906235 0.050584702 1.57E-06 5.802993499 0.193442603 KWST(ph)S(ph)T(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 KWSTSTK 7 1 Q9H4Z2-2;Q9H4Z2 Q9H4Z2-2 ZNF335 Zinc finger protein 335 3 0 KWS(0.023)T(0.977)S(1)T(1)K 58.433 0.020218 285640000 4549.1 4090.3 4302.1 4275.1 4370.7 4793.5 3584.1 3105 4703.4 4087.1 TRUE FALSE FALSE 4189.033935 4443.847306 4461.539611 4257.410769 4318.582257 3799.274066 3684.6602 4051.700206 4187.448787 4229.126421 0.990519913 1.050771924 1.054955366 1.006687988 1.02115232 0.898359067 0.871257994 0.958046604 0.990145096 1 12.04614397 -5.258858529 24.99895222 1.006586087 0.905424893 0.720668056 0.030103678 98.61151782 955175.2555 0.004475197 0.010852685 5.51E-06 5.258858529 -0.101161195 KY(ph)ADALQEIIQER ddPTM_HeLa_Curcumin_4h_R1 1 KYADALQEIIQER 13 1 H3BNX3;Q9Y6N5 H3BNX3 SQRDL "Sulfide:quinone oxidoreductase, mitochondrial" 1 0 KY(1)ADALQEIIQER 84.687 0.013564 36007000 2960.6 2347.4 2654 2919.1 2630.1 3586.3 2740.9 2671 3301 2842.8 TRUE FALSE FALSE 2726.265386 2550.298796 2752.359575 2907.021538 2598.737775 2842.460954 2817.802277 3485.375604 2938.888559 2941.587088 0.926800841 0.866980552 0.935671626 0.988249353 0.883447505 0.966301819 0.957919039 1.184862287 0.999082628 1 11.52237903 -4.260687207 5.778561946 0.951732812 1.192140811 0.72904638 0.04340892 0.06065963 8.7610961 0.006448537 0.057055573 5.49E-05 4.260687207 0.240407999 KYDEELEER ddPTM_HeLa_Curcumin_4h_R1 2 KYDEELEER 9 1 Q01995;E9PJ32 Q01995 TAGLN Transgelin 0 0 ; ; 94.363 0.0045403 21040200 20534.9 16240.8 18602.5 18800.4 19316.6 22523.8 19795.5 17637.3 19258.1 16111 FALSE FALSE TRUE 18909.541 17644.58238 19291.92501 18722.60893 19086.26216 17852.10998 20350.90845 23014.83158 17145.53461 16670.85605 1.134287342 1.058408898 1.157224617 1.123074236 1.144887947 1.070857425 1.220747656 1.380542877 1.028473556 1 14.02504057 -1 0.514182491 1.06834028 11.522624 0.762634599 0.050592211 43.25147013 0.400069039 0.011922815 494.5558227 0.1 1 10.45428372 KYEDICPSTHNMDVPNIK ddPTM_HeLa_Curcumin_4h_R1 1 KYEDICPSTHNMDVPNIK 18 1 I3L397;I3L504;P63241;P63241-2;F8WCJ1;C9J7B5;C9J4W5;Q9GZV4;Q6IS14 I3L397 EIF5A;EIF5A2;EIF5AL1 Eukaryotic translation initiation factor 5A;Eukaryotic translation initiation factor 5A-1;Eukaryotic translation initiation factor 5A-2;Eukaryotic translation initiation factor 5A-1-like 0 0 81.428 0.0014967 29595000 1013.1 863.51 785.95 852.23 1361.6 1583.2 897.12 682.57 940.17 1006.6 FALSE FALSE TRUE 932.912066 938.1479567 815.0779984 848.7036981 1345.363809 1254.826474 922.2907727 890.6824508 837.0357032 1041.579275 0.895670726 0.900697603 0.78254053 0.814823911 1.291657622 1.204734487 0.885473429 0.855126894 0.803621696 1 10.02455693 KYEQGFITDPVVLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 KYEQGFITDPVVLSPK 16 1 P12268;H0Y4R1 P12268 IMPDH2 Inosine-5-monophosphate dehydrogenase 2 1 0 KYEQGFITDPVVLS(1)PK;KYEQGFITDPVVLS(1)PK ; 114.46 0.00060479 76249000 10610.3 9698 10430.2 9317.7 11780.9 16060.2 12105.6 11571.6 9951.1 8911.3 TRUE FALSE FALSE 9770.483559 10536.25191 10816.75239 9279.145826 11640.42046 12729.13348 12445.25056 15099.72757 8859.489226 9220.967012 1.059594243 1.142640668 1.173060523 1.006309405 1.262386087 1.380455376 1.3496687 1.637542738 0.960798278 1 13.17070234 -1 0.311282582 1.009343739 6.68143139 0.882723234 0.069231193 10.56621551 0.135023452 0.022783569 34.26981899 0.1 1 5.672087651 KYES(ph)DEDS(ph)LGSSGR ddPTM_HeLa_Curcumin_4h_R1 2 KYESDEDSLGSSGR 14 1 O00418 O00418 EEF2K Eukaryotic elongation factor 2 kinase 2 0 KY(0.002)ES(0.998)DEDS(0.887)LGS(0.101)S(0.012)GR;KY(0.006)ES(0.993)DEDS(1)LGS(0.001)SGR ; 132.4 0.0015551 89386000 25885.2 20270.9 24046.8 24085.1 24862 29679 20968.2 11532.7 26654.2 23831.5 TRUE FALSE FALSE 23836.35911 22023.02627 24937.99556 23985.44224 24565.53689 23523.24085 21556.51126 15048.96714 23730.30095 24659.64285 0.966614125 0.893079693 1.011287784 0.972659758 0.996183807 0.953916526 0.874161535 0.610267036 0.962313246 1 14.58986428 -4.183440574 1.697809044 0.978790699 0.429455158 0.922529169 0.031369396 0.216269417 0.515560977 0.004561496 0.20431214 6.55E-05 4.183440574 -0.54933554 TEDFQTPS(ph)PVLR ddPTM_HeLa_Curcumin_4h_R1 1 TEDFQTPSPVLR 12 0 Q5VT06;H0Y7F7 Q5VT06 CEP350 Centrosome-associated protein 350 1 0 TEDFQT(0.015)PS(0.985)PVLR 118.08 0.0037617 8722500 939.94 968.95 958.64 921.01 855.38 953.42 545.75 239.48 1041.1 966.89 TRUE FALSE FALSE 865.5427572 1052.70172 994.1680417 917.1991047 845.1801522 755.6699447 561.0622762 312.4963496 926.8939347 1000.489356 0.865119406 1.052186827 0.993681778 0.916750488 0.844766761 0.755300334 0.560787852 0.312343503 0.926440576 1 9.966490103 -4.397376921 0.897670195 0.949475869 0.040474527 0.946294484 0.05017858 0.354631797 0.24266354 0.010122024 0.299899242 4.01E-05 4.397376921 -0.909001342 down KYESDEDS(ph)LGSSGR ddPTM_HeLa_Curcumin_4h_R1 1 KYESDEDSLGSSGR 14 1 O00418 O00418 EEF2K Eukaryotic elongation factor 2 kinase 1 0 KYES(0.002)DEDS(0.981)LGS(0.015)S(0.003)GR 123.76 0.00047835 0 1366 927.63 1074 1248.8 1286.2 1410.6 1333.2 971.37 1499 1144 TRUE FALSE FALSE 1257.879659 1007.810204 1113.803385 1243.632796 1270.862905 1118.025659 1370.606004 1267.536241 1334.56345 1183.753915 1.062619217 0.851368001 0.940907879 1.050583893 1.073587077 0.94447473 1.157847072 1.070776811 1.127399397 1 10.20915348 -4.753496064 24.99960905 1.011184955 1.114311944 0.233931287 0.077745678 187.8443177 591178.5363 0.009908471 0.035755037 1.76E-05 4.753496064 0.103126989 KYFLHDDRDDGVDYWAK ddPTM_HeLa_Curcumin_4h_R1 1 KYFLHDDRDDGVDYWAK 17 2 Q9NYF8-2;Q9NYF8;Q9NYF8-4;H0YF14 Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 0 82.578 0.0028008 17481000 8696.6 6206.9 7333.3 7129.1 6400.5 9623.5 7928 7541.1 9137.5 7748.3 FALSE FALSE TRUE 8008.254933 6743.396779 7605.078549 7099.601673 6324.178218 7627.477621 8150.438343 9840.346675 8135.139111 8017.552848 0.998840305 0.84107918 0.948553591 0.885507312 0.788791585 0.951347346 1.016574321 1.227350397 1.014666104 1 12.96894624 -4.282132334 2.797169682 0.959046726 1.269863067 0.575622269 0.074119964 0.271562379 2.981587525 0.011828885 0.187900756 5.22E-05 4.282132334 0.310816341 DLS(ph)TPGLEK ddPTM_HeLa_Curcumin_4h_R1 6 DLSTPGLEK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 DLS(0.5)T(0.5)PGLEK;DLS(0.704)T(0.296)PGLEK;DLS(0.5)T(0.5)PGLEK;DLS(0.925)T(0.075)PGLEK;DLS(0.5)T(0.5)PGLEK;DLS(0.5)T(0.5)PGLEK ;;;;; 163.66 0.00043193 293197900 34041.1 27572.01 33468.2 33844.8 30081.8 35487.4 38587.5 95297.8 24340.4 25667.6 TRUE FALSE FALSE 31346.71101 29955.21169 34708.56093 33704.75919 29723.09418 28126.91321 39670.1614 124353.6605 21670.31902 26559.54719 1.180242675 1.127850994 1.306820507 1.269026123 1.119111481 1.059013281 1.493630939 4.682070053 0.815914476 1 14.69694293 -4.25792488 3.603992941 1.122096506 5.10204841 0.984925345 0.131747224 0.019885799 0.460005514 0.015827593 0.213580356 5.52E-05 4.25792488 3.979951905 up KYIEIDS(ph)DEEPRGELLSLR ddPTM_HeLa_Curcumin_4h_R1 1 KYIEIDSDEEPRGELLSLR 19 2 E7EW05;Q9NVU7-2;Q9NVU7 E7EW05 SDAD1 Protein SDA1 homolog 1 0 KYIEIDS(0.99)DEEPRGELLS(0.01)LR 64.749 0.010862 11949000 826.31 693.67 782.1 883.19 804.5 1155.9 619.14 733.93 851.14 688.99 TRUE FALSE FALSE 760.9066916 753.6277439 811.085314 879.5355938 794.9068629 916.1533103 636.5114021 957.7018784 757.7720714 712.9323512 1.067291574 1.057081703 1.137675002 1.233687309 1.114982174 1.285049428 0.892807573 1.343327844 1.062894776 1 9.477621378 -7.120587385 0.952059586 1.021953377 1.163633038 0.198878699 0.115455216 0.529270811 0.947098636 0.022558177 0.02892802 7.58E-08 7.120587385 0.141679661 KYTLENKEEGSLS(ph)DTEADAVSGQLPDPTTNPSAGK ddPTM_HeLa_Curcumin_4h_R1 1 KYTLENKEEGSLSDTEADAVSGQLPDPTTNPSAGK 35 2 Q8N1G4 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 1 0 KYTLENKEEGS(0.022)LS(0.395)DT(0.251)EADAVS(0.331)GQLPDPTTNPSAGK 68.441 4.91E-06 116290000 2918 2695 2947 2775.8 3354.7 3154.3 2674.7 2654.4 3144.4 3026.6 TRUE FALSE FALSE 2687.037221 2927.943791 3056.218412 2764.314475 3314.697394 2500.062624 2749.744883 3463.714341 2799.467187 3131.774125 0.857992024 0.934915379 0.975874469 0.882667257 1.058408832 0.798289571 0.878015072 1.10599111 0.893891793 1 11.61276445 -6.987528549 24.29158062 0.931020307 0.94274622 0.015363712 0.090145103 1708.911609 3328558.424 0.015185343 0.019950384 1.03E-07 6.987528549 0.011725913 LAAAEETAVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 LAAAEETAVSPR 12 0 Q9BUH6 Q9BUH6 C9orf142 Protein PAXX 1 0 LAAAEETAVS(1)PR;LAAAEETAVS(1)PR;LAAAEETAVS(1)PR ;; 197.38 1.84E-06 845186000 5821.4 4427.82 5360.4 5515.97 5773.93 7072.7 5958.3 6646.2 5744 4427.08 TRUE FALSE FALSE 5360.630047 4810.541031 5559.061139 5493.146378 5705.079656 5605.742294 6125.473862 8672.595785 5113.897571 4580.9207 1.170207999 1.050125367 1.213524857 1.199135881 1.245400222 1.223715201 1.337170901 1.893199283 1.116347107 1 12.16142187 -1 0.645598252 1.093662418 67.06187538 0.905361943 0.072300402 47.25178509 0.287345687 0.014839615 4460.185884 0.1 1 65.96821297 LAAIAESGVER ddPTM_HeLa_Curcumin_4h_R1 1 LAAIAESGVER 11 0 P28072 P28072 PSMB6 Proteasome subunit beta type-6 0 0 96.89 0.013656 3345500 3475.5 3152.9 2850.3 3027.4 3248.8 4592.5 3711.7 3274.7 3998.7 3152.2 FALSE FALSE TRUE 3200.410508 3425.422627 2955.934625 3014.873421 3210.060182 3639.963732 3815.840312 4273.140955 3560.052614 3261.738715 0.981197695 1.050183024 0.906245068 0.924314816 0.984156139 1.115958098 1.16987921 1.310080705 1.091458552 1 11.6714255 -4.707191387 1.4027829 0.983309723 1.319486433 0.779754308 0.054730051 0.163783298 0.479396143 0.006519423 0.061434085 1.96E-05 4.707191387 0.33617671 LAALSS(ph)RVGEVEQEAETARK ddPTM_HeLa_Curcumin_4h_R1 1 LAALSSRVGEVEQEAETARK 20 2 H0YH95;H0YHK3;G3V200;O75334-6;O75334-5;O75334-2;O75334-4;O75334-3;O75334 H0YH95 PPFIA2 Liprin-alpha-2 1 0 LAALS(0.195)S(0.805)RVGEVEQEAETARK 55.734 0.016705 46440000 1481.7 1456.7 1569.3 1268.8 1177.1 1338.5 1761.4 1453.5 1387.5 1680.3 TRUE FALSE FALSE 1364.421882 1582.610657 1627.459638 1263.550042 1163.063851 1060.880012 1810.820143 1896.665459 1235.294721 1738.6903 0.784741182 0.910231487 0.936026179 0.726725192 0.668931006 0.610160425 1.041485159 1.090858711 0.71047427 1 10.76378526 -9.42562196 1.014690132 1.005505171 0.83511001 0 0.172182918 0.97799886 1.704488297 0.126444664 0.027913015 3.75E-10 9.42562196 -0.170395161 LAAPSVSHVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 LAAPSVSHVSPR 12 0 A0A0U1RRM7;A0A0U1RQW3;A0A0U1RQJ8;Q8WXE1-5;Q8WXE1-3;Q8WXE1-2;Q8WXE1 A0A0U1RRM7 ATRIP ATR-interacting protein 1 0 LAAPSVSHVS(1)PR 134.02 0.00092286 22072000 3628.5 3271.2 2956.2 2809.7 4945.2 8397.4 3199.6 1898.4 5031.9 3247.2 TRUE FALSE FALSE 3341.300396 3553.947952 3065.759373 2798.074206 4886.23172 6655.684582 3289.372165 2477.213421 4479.913159 3360.039958 0.994422816 1.057710026 0.912417534 0.832750277 1.454218337 1.98083495 0.978968169 0.737257131 1.333291632 1 11.71426267 -5.760044082 24.99985156 0.984966077 1.315259927 0.129737615 0.32632038 46.21062929 827936.3912 0.045393854 0.086989721 1.74E-06 5.760044082 0.33029385 LAAQESS(ph)EAEDMSVPR ddPTM_HeLa_Curcumin_4h_R1 1 LAAQESSEAEDMSVPR 16 0 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1-5;Q5SRD0 A0A0A0MR88 FAM21C;FAM21D WASH complex subunit FAM21C;Putative WASH complex subunit FAM21 1 0 LAAQES(0.252)S(0.748)EAEDMSVPR 152.37 0.00033634 4910100 1121.6 1014.9 1154.7 1218.6 915.87 1274.7 1220.8 871.78 1275.2 1063.7 TRUE FALSE FALSE 1032.824176 1102.623434 1197.494198 1213.557756 904.9488484 1010.312851 1255.052362 1137.581709 1135.31375 1100.663496 0.938365068 1.001780688 1.087974846 1.102569278 0.822184847 0.917912564 1.140268908 1.03354178 1.031481243 1 10.10415775 -7.014132119 23.6910062 0.970851362 1.016085316 0.005404597 0.090105571 884.2830148 1482408.831 0.015244181 0.019086132 9.68E-08 7.014132119 0.045233954 LAAQESS(ph)ETEDMSVPR ddPTM_HeLa_Curcumin_4h_R1 4 LAAQESSETEDMSVPR 16 0 Q641Q2;F8W7U3;E7ESD2;Q641Q2-2;A0A087WYF6 Q641Q2 FAM21A WASH complex subunit FAM21A 1 0 LAAQES(0.108)S(0.44)ET(0.44)EDMS(0.011)VPR;LAAQES(0.066)S(0.439)ET(0.439)EDMS(0.055)VPR;LAAQES(0.008)S(0.802)ET(0.19)EDMSVPR;LAAQES(0.083)S(0.909)ET(0.008)EDMSVPR ;;; 213.94 4.38E-15 35726100 11738.7 11039.6 11496.4 11678.2 12440 15216.3 11866.5 7987.5 12606.1 11149.1 TRUE FALSE FALSE 10809.56951 11993.81383 11922.4667 11629.8787 12291.66112 12060.26786 12199.44205 10422.85198 11223.24237 11536.5304 0.936986177 1.039637865 1.033453412 1.008091541 1.065455618 1.045398178 1.057461961 0.903465047 0.972843826 1 13.49392178 -7.248708255 24.82372032 0.970243472 1.025721216 0.213296778 0.045257683 764.5153011 1490686.426 0.007676143 0.009367796 5.64E-08 7.248708255 0.055477744 LAAQLGAPT(ph)SPIPDSAIVNTR ddPTM_HeLa_Curcumin_4h_R1 1 LAAQLGAPTSPIPDSAIVNTR 21 0 Q9H8Y5;B8ZZS4 Q9H8Y5 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 0 LAAQLGAPT(0.475)S(0.475)PIPDS(0.05)AIVNTR 85.271 0.0023937 8839500 1986 1801.4 1508.1 1610.9 1313.5 2282.7 1932.5 2139.8 1828.2 1621.8 TRUE FALSE FALSE 1828.806004 1957.104989 1563.991513 1604.234523 1297.83737 1809.242289 1986.720749 2792.21517 1627.651034 1678.157429 1.089770228 1.166222522 0.931969484 0.955949957 0.773370452 1.078112373 1.183870306 1.663857705 0.969903661 1 10.71266235 -4.252707823 2.101209415 1.020699293 1.85089091 0.79459161 0.102255072 0.255990884 1.207970487 0.015291918 0.404324374 5.59E-05 4.252707823 0.830191617 LAAQLGAPTS(ph)PIPDSAIVNTR ddPTM_HeLa_Curcumin_4h_R1 1 LAAQLGAPTSPIPDSAIVNTR 21 0 Q9H8Y5;B8ZZS4 Q9H8Y5 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 0 LAAQLGAPT(0.017)S(0.983)PIPDSAIVNTR 142.58 3.50E-05 13010000 3317.5 2980.4 2878.4 2583.8 2658.2 3297.5 3302.5 3357.1 3167.5 2373 TRUE FALSE FALSE 3054.916374 3238.012496 2985.076036 2573.10892 2626.502701 2613.56133 3395.159262 4380.664336 2820.033175 2455.461573 1.244131208 1.318698094 1.215688353 1.047912518 1.069657424 1.06438698 1.382696964 1.784049233 1.148473756 1 11.26177853 -4.392956862 2.529944353 1.128728983 1.836649654 0.809780591 0.095984777 0.149210351 1.427431346 0.017301599 0.196742162 4.05E-05 4.392956862 0.707920671 LADAMAES(ph)PSRDVVGSGTELQR ddPTM_HeLa_Curcumin_4h_R1 1 LADAMAESPSRDVVGSGTELQR 22 1 K7ESE9;Q9H6U6-6;Q9H6U6-2;Q9H6U6 K7ESE9 BCAS3 Breast carcinoma-amplified sequence 3 1 0 LADAMAES(0.561)PS(0.428)RDVVGS(0.008)GT(0.004)ELQR 61.561 0.00356 11725000 895.19 547.31 797.97 798.43 707.34 1015.1 648.18 496.09 867.56 969.92 TRUE FALSE FALSE 824.3347669 594.6170376 827.5434702 795.1263082 698.9054325 804.5568175 666.3661863 647.3455573 772.3908385 1003.624648 0.821357635 0.592469544 0.82455475 0.792254664 0.696381296 0.801651115 0.663959567 0.645007632 0.769601305 1 9.971004092 -8.530184632 0.403442748 1.043085565 0.700504271 0.132579876 0.103273251 0.636265207 0.207003934 0.092241886 0.031122285 2.95E-09 8.530184632 -0.342581294 LADDVDLEQVANETHGHVGADLAALCSEAALQAIR ddPTM_HeLa_Curcumin_4h_R1 1 LADDVDLEQVANETHGHVGADLAALCSEAALQAIR 35 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 103.15 1.62E-14 10035000 1700.1 1407.1 1283.7 1385.3 1370.1 2102.2 2010.1 1508.8 1946.3 1361.1 FALSE FALSE TRUE 1565.535291 1528.723454 1331.275051 1379.567996 1353.762452 1666.180023 2066.497996 1968.826174 1732.795759 1408.398124 1.111571554 1.085434174 0.945240574 0.979529845 0.961207225 1.183031982 1.467268354 1.397918771 1.23033092 1 10.45983949 -4.921457934 3.601094735 1.037646238 1.432092637 0.774733941 0.082552105 0.06022406 1.538222961 0.009511641 0.031966552 1.20E-05 4.921457934 0.3944464 LADFGVLHR ddPTM_HeLa_Curcumin_4h_R1 2 LADFGVLHR 9 0 P26639;P26639-2 P26639 TARS "Threonine--tRNA ligase, cytoplasmic" 0 0 ; ; 123.21 0.00076512 13836550 11690.5 6443.53 9556.45 8574.98 10823.53 18288.9 11103.25 12176.82 9849.02 7950.56 FALSE FALSE TRUE 10765.18459 7000.480021 9910.620444 8539.499005 10694.46647 14495.57598 11414.77731 15889.47636 8768.607147 8226.841368 1.308544082 0.850931689 1.204668961 1.038004578 1.29994806 1.761985595 1.387504244 1.931418834 1.065853437 1 13.00612291 -5.430706371 3.751416812 1.123340419 1.661376641 0.709782646 0.173880248 0.111612115 2.885036664 0.02586067 0.060157576 3.71E-06 5.430706371 0.538036222 FDGSENRPFS(ph)PSPLNNISSTVTVK ddPTM_HeLa_Curcumin_4h_R1 2 FDGSENRPFSPSPLNNISSTVTVK 24 1 Q5UIP0-2;Q5UIP0 Q5UIP0-2 RIF1 Telomere-associated protein RIF1 1 0 FDGS(0.114)ENRPFS(0.727)PS(0.152)PLNNIS(0.006)S(0.001)TVTVK;FDGS(0.015)ENRPFS(0.697)PS(0.255)PLNNIS(0.015)S(0.015)T(0.003)VT(0.001)VK ; 64.589 0.0011113 76463000 2810.8 2284.9 2793 3315.5 2944.5 2990.5 1895.52 723.47 3370.4 3195 TRUE FALSE FALSE 2588.322214 2482.396575 2896.511037 3301.781339 2909.388761 2370.23659 1948.70319 944.0526726 3000.675552 3306.026012 0.78291042 0.750870249 0.876130746 0.99871608 0.880025974 0.716944326 0.589439763 0.285555125 0.907638216 1 11.69088236 -4.397349268 1.182170258 0.889733098 0.098677223 0.854263134 0.077992335 0.427071007 0.57714714 0.015410698 0.388763314 4.01E-05 4.397349268 -0.791055874 down LADLEEESESWDNS(ph)EAEEEEKAPVLPESTEGR ddPTM_HeLa_Curcumin_4h_R1 2 LADLEEESESWDNSEAEEEEKAPVLPESTEGR 32 1 Q8NFG4 Q8NFG4 FLCN Folliculin 1 0 LADLEEES(0.007)ES(0.044)WDNS(0.95)EAEEEEKAPVLPESTEGR;LADLEEESES(0.039)WDNS(0.961)EAEEEEKAPVLPESTEGR ; 94.031 5.60E-09 4544300 960.2 628.78 581.62 733.92 801.2 810.49 668.72 390.21 818.75 797.36 TRUE FALSE FALSE 884.1991568 683.1289414 603.1753488 730.8832335 791.6462133 642.3852379 687.4824834 509.1832327 728.9351734 825.0682006 1.071667962 0.827966635 0.7310612 0.88584584 0.959491849 0.77858441 0.833243219 0.61714078 0.883484751 1 9.688369568 -7.234389121 8.459151427 1.033845845 0.810871141 0.381642418 0.099306858 0.15361722 44.32385152 0.014643219 0.01780333 5.83E-08 7.234389121 -0.222974705 LADSGDGAGPS(ph)PEEKDFLK ddPTM_HeLa_Curcumin_4h_R1 2 LADSGDGAGPSPEEKDFLK 19 1 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 1 0 LADS(0.002)GDGAGPS(0.998)PEEKDFLK;LADS(0.001)GDGAGPS(0.999)PEEKDFLK ; 93.255 0.00070366 248220000 9490.5 7601.8 8461.8 8526.6 8617.8 10790.4 9488.3 12043.2 9386.5 8526.3 TRUE FALSE FALSE 8739.316911 8258.865719 8775.401752 8491.319188 8515.038363 8552.349407 9754.516162 15715.11624 8356.824434 8822.58829 0.99056157 0.936104627 0.994651622 0.962452164 0.965140624 0.96936966 1.105629759 1.781236495 0.947207799 1 13.10698625 -4.254379855 2.980769904 0.985593526 1.920516063 0.990274608 0.023943567 0.025508196 0.322759906 0.0032709 0.057071029 5.57E-05 4.254379855 0.934922537 LADVDKDGLLDDEEFALANHLIK ddPTM_HeLa_Curcumin_4h_R1 1 LADVDKDGLLDDEEFALANHLIK 23 1 A0A024R571;Q9H4M9 A0A024R571 EHD1 EH domain-containing protein 1 0 0 115.53 2.03E-06 19688000 3604.4 3704.9 3273 3518.2 3305.5 4637.1 2997.5 3332.1 4538 3518 FALSE FALSE TRUE 3319.107937 4025.135047 3394.300259 3503.642621 3266.084071 3675.313189 3081.601783 4348.041951 4040.192754 3640.250238 0.911780158 1.105730316 0.932435969 0.962473015 0.897214163 1.009632017 0.8465357 1.194434906 1.109866764 1 11.82982191 -4.242906138 24.63560333 0.959693199 1.194435155 0.378022373 0.082311641 2050.252245 2725279.638 0.008847882 0.402048033 5.72E-05 4.242906138 0.234741956 LAEAFAEELHER ddPTM_HeLa_Curcumin_4h_R1 1 LAEAFAEELHER 12 0 B1ANE3;Q99707-2;Q99707 B1ANE3 MTR Methionine synthase 0 0 115.37 0.0019335 0 1163.4 740.03 782.99 948.36 878.01 1204.6 750.46 791.71 940.69 775.03 FALSE FALSE TRUE 1071.315662 803.9948957 812.0082982 944.4359376 867.5403042 954.7523814 771.5158878 1033.098734 837.4986605 801.9622348 1.33586797 1.002534609 1.012526853 1.177656374 1.081772017 1.190520376 0.962035186 1.288213696 1.044311844 1 9.64739049 LAEDEGDS(ph)EPEAVGQSR ddPTM_HeLa_Curcumin_4h_R1 2 LAEDEGDSEPEAVGQSR 17 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 0 LAEDEGDS(1)EPEAVGQSR;LAEDEGDS(1)EPEAVGQSR ; 305.9 2.39E-95 926610000 5462.05 4110.15 4392.41 6022.9 4912.5 6398.2 5143.43 2884.95 6134 4210.27 TRUE FALSE FALSE 5029.722979 4465.413052 4555.196579 5997.978836 4853.921646 5071.141197 5287.740803 3764.557974 5461.115547 4356.576569 1.1545127 1.024982112 1.045590846 1.376764241 1.114159609 1.164019757 1.213737603 0.864109218 1.2535337 1 12.08897918 -9.496735536 0.676235771 0.975509412 1.131428492 0 0.149060583 1.925504049 1.161603343 0.187090605 0.025247251 3.19E-10 9.496735536 0.155919079 LAEQAER ddPTM_HeLa_Curcumin_4h_R1 2 LAEQAER 7 0 P27348;E9PG15;P31946-2;P31946;Q4VY20;Q4VY19;A0A0J9YWE8;P63104;E7EX29;E7ESK7;E5RIR4;E9PD24;E7EVZ2;E5RGE1;P62258;B4DJF2;I3L3T1;I3L0W5;P31947-2;P31947;P61981;Q04917;F8WEB6;A2IDB1 P27348;P31946-2;P63104;P62258;P31947-2;P61981;Q04917 YWHAQ;YWHAB;YWHAZ;YWHAE;SFN;YWHAG;YWHAH "14-3-3 protein theta;14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed;14-3-3 protein zeta/delta;14-3-3 protein epsilon;14-3-3 protein sigma;14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed;14-3-3 protein eta" 0 0 ; ; 134.81 0.0060709 60392000 12160.7 14919.5 12226.2 9945.6 10447.6 13022.2 10345.9 10094.4 9564.9 11509.3 FALSE FALSE TRUE 11198.16776 16209.0751 12679.31373 9904.447742 10323.01919 10321.24893 10636.17811 13172.13609 8515.6544 11909.24732 0.940291814 1.361049499 1.064661216 0.831660262 0.866807021 0.866658375 0.893102463 1.106042703 0.715045559 1 13.53979462 -6.269189119 24.7939102 1.012805324 0.90663224 0.090210072 0.163339663 908.3096998 2905973.413 0.02185941 0.033789289 5.38E-07 6.269189119 -0.106173084 LAGAS(ph)PATVAAAAAAGSGPKDPMAR ddPTM_HeLa_Curcumin_4h_R1 1 LAGASPATVAAAAAAGSGPKDPMAR 25 1 Q13045;Q13045-3 Q13045 FLII Protein flightless-1 homolog 1 0 LAGAS(0.576)PAT(0.424)VAAAAAAGSGPKDPMAR 49.515 0.010593 19943000 1081.4 840.82 1057.3 1061.9 1000.9 1381.1 779.01 606.81 1216.4 1187 TRUE FALSE FALSE 995.8060489 913.4967342 1096.484468 1057.506139 988.9649212 1094.644292 800.866924 791.8235756 1082.963963 1228.248162 0.810753136 0.743739549 0.892722255 0.860987358 0.805183311 0.891224042 0.652039994 0.644677192 0.881714296 1 10.26238636 -13.52287875 0.033025479 2.201933736 1.49E-11 0.453390105 0.078692922 543.4993497 1.439001911 75.94602746 29.95044714 3.00E-14 13.52287875 -2.201933736 LAGEDKDSEPAADGPAASEDPSATESDLPNPHVGEVSVLSSGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 LAGEDKDSEPAADGPAASEDPSATESDLPNPHVGEVSVLSSGSPR 45 1 O14686;O14686-3;F8VWW4 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 0 LAGEDKDSEPAADGPAAS(0.001)EDPS(0.022)AT(0.022)ES(0.022)DLPNPHVGEVS(0.134)VLS(0.104)S(0.221)GS(0.474)PR;LAGEDKDSEPAADGPAASEDPSATESDLPNPHVGEVS(0.021)VLS(0.073)S(0.158)GS(0.747)PR ; 92.944 6.83E-17 37674000 4893.2 3451.9 3506.1 4020.3 4686.9 5889.2 3229.2 1877.2 5074.6 3775.7 TRUE FALSE FALSE 4505.898057 3750.266855 3636.03915 4003.665064 4631.011779 4667.713535 3319.802661 2449.549638 4517.929076 3906.905294 1.153316428 0.959907285 0.930669898 1.024766346 1.185340168 1.194734242 0.849726935 0.626979528 1.156395852 1 11.93181057 -4.514036448 3.903719508 1.066677672 0.655518539 0.70542608 0.092158635 0.094500947 3.11839161 0.013916146 0.076702198 3.06E-05 4.514036448 -0.411159133 LAGESESNLRK ddPTM_HeLa_Curcumin_4h_R1 1 LAGESESNLRK 11 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 79.201 0.013182 2534500 1376.2 1130 1120.1 1203.1 1117.8 1559.9 1358.9 1365.9 1500 1105.9 FALSE FALSE TRUE 1267.272318 1227.672165 1161.611891 1198.121891 1104.470965 1236.359156 1397.027077 1782.356622 1335.453753 1144.329943 1.107436125 1.072830588 1.015102243 1.047007376 0.965168282 1.080421922 1.220825415 1.557554824 1.167018098 1 10.16028737 -4.295801313 1.850376323 1.044982571 1.698973659 0.887654552 0.054292175 0.156430615 0.571890493 0.00702444 0.172203657 5.06E-05 4.295801313 0.653991088 LAGPAS(ph)PPAGGSSGGVETTVDFYGR ddPTM_HeLa_Curcumin_4h_R1 1 LAGPASPPAGGSSGGVETTVDFYGR 25 0 O00358 O00358 FOXE1 Forkhead box protein E1 1 0 LAGPAS(0.992)PPAGGS(0.007)S(0.001)GGVETTVDFYGR 52.158 0.0070969 3226100 1063.8 970 753.34 1057 1020.6 1298 757.72 729.59 1108 1093 TRUE FALSE FALSE 979.5991075 1053.842478 781.2594431 1052.626414 1008.430012 1028.780169 778.9795839 952.0386324 986.4551721 1130.981669 0.866149412 0.931794482 0.690779935 0.930719253 0.891641341 0.909634698 0.688764111 0.841780781 0.87221146 1 10.14335983 -13.52287875 0.139959375 1.586341315 0.77793325 0.088151419 0.091412826 57.20111442 0.556997777 9.208397309 0.232350564 3.00E-14 13.52287875 -0.808408065 LAGTSGSDK(ac)GLSGK ddPTM_HeLa_Curcumin_4h_R1 1 LAGTSGSDKGLSGK 14 1 Q9P016-2;Q9P016 Q9P016-2 THYN1 Thymocyte nuclear protein 1 0 1 LAGTSGSDK(1)GLSGK 137.84 0.0011943 1252500 732.76 700.25 670.27 880.6 839.36 840.08 757.37 810.26 700.19 831.15 FALSE TRUE FALSE 674.7612728 760.7764897 695.1107958 876.9563105 829.3511802 665.8379383 778.6197638 1057.304544 623.3809088 860.0324006 0.784576572 0.884590498 0.808237917 1.019678224 0.964325506 0.774200993 0.90533771 1.229377571 0.724834214 1 9.748247202 -6.250052912 24.22125155 0.888305772 0.962368005 0.170790745 0.13024003 1151.990107 2450504.944 0.020047612 0.03302954 5.62E-07 6.250052912 0.074062233 LAHEVGWK ddPTM_HeLa_Curcumin_4h_R1 3 LAHEVGWK 8 0 Q8J015;M0QYS1;P40429 Q8J015 RPL13a;RPL13A 60S ribosomal protein L13a 0 0 ;; ;; 96.253 0.0049166 53621700 31362.7 25170.8 25704.9 26371.6 27191.6 31493.2 24919 23713 27631.1 24972 FALSE FALSE TRUE 28880.3092 27346.45179 26657.54621 26262.48131 26867.35793 24961.15532 25618.16007 30942.98454 24600.03746 25839.77514 1.117668751 1.058308427 1.031647762 1.01635874 1.039767482 0.965997389 0.991423491 1.197494342 0.952022118 1 14.6573059 -6.763207366 22.38159098 1.057324074 1.033709757 0 0.071803544 47.47034477 600966.4071 0.011164819 0.015114856 1.73E-07 6.763207366 -0.023614317 LAIK(ac)LPDDQIPK ddPTM_HeLa_Curcumin_4h_R1 1 LAIKLPDDQIPK 12 1 Q01813;Q01813-2;B1APP6 Q01813 PFKP "ATP-dependent 6-phosphofructokinase, platelet type" 0 1 LAIK(1)LPDDQIPK 168.3 1.76E-33 0 183.75 384.61 192.3 195.88 279.37 527.02 243.65 275.52 436.48 132.78 FALSE TRUE FALSE 169.2059936 417.8539746 199.4268072 195.0695005 276.0386952 417.7101113 250.4861632 359.5247797 388.599236 137.3940951 1.231537596 3.041280444 1.451494746 1.419780816 2.009101592 3.040233359 1.823121751 2.61674113 2.82835471 1 7.102176192 -7.042594113 0.383344004 0.896789315 2.488986868 0 0.826102301 0.798739707 0.30930994 0.331864446 0.473043829 9.07E-08 7.042594113 1.592197553 LAILGIHNEVSK ddPTM_HeLa_Curcumin_4h_R1 2 LAILGIHNEVSK 12 0 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8 P12814-4 ACTN1 Alpha-actinin-1 0 0 ; ; 129.89 0.00012912 4466100 4590.8 2783.3 4260.3 2749.3 4593.2 7135.4 5369.6 5038.4 3549.6 2878.7 FALSE FALSE TRUE 4227.433336 3023.87605 4418.190466 2737.924125 4538.42909 5655.437607 5520.256524 6574.584966 3160.217761 2978.734611 1.419204423 1.015154569 1.483244076 0.919156784 1.523609748 1.898604054 1.853222004 2.207173792 1.060926257 1 11.54048388 -5.372404893 2.485028536 1.193234177 1.999294579 0.785094124 0.194921127 0.110697325 1.3213543 0.030588522 0.080411922 4.24E-06 5.372404893 0.806060402 LAIQGPEDS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 LAIQGPEDSPSR 12 0 Q15773 Q15773 MLF2 Myeloid leukemia factor 2 1 0 LAIQGPEDS(0.938)PS(0.062)R;LAIQGPEDS(0.5)PS(0.5)R ; 204.17 6.27E-09 829020000 7356 5484 5610 5612.6 5469.5 7481.5 6555.2 4944.4 6397.2 5133.1 TRUE FALSE FALSE 6773.764838 5958.012524 5817.911535 5589.376548 5404.279785 5929.752566 6739.12127 6451.924799 5695.443165 5311.474843 1.275307714 1.1217247 1.095347659 1.052321006 1.017472537 1.116404152 1.268785313 1.214714366 1.07229034 1 12.3748968 -4.769549139 24.29051455 1.115218111 1.241749839 0.358219586 0.074938206 145.4949637 435798.0758 0.01520915 0.046866925 1.70E-05 4.769549139 0.126531727 LAIQGPEDSPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 LAIQGPEDSPSR 12 0 Q15773 Q15773 MLF2 Myeloid leukemia factor 2 1 0 LAIQGPEDS(0.1)PS(0.9)R;LAIQGPEDS(0.1)PS(0.9)R ; 174.24 0.0001392 512540000 8807.6 6832.8 6963.6 7307.4 7172.7 10609.1 7592.1 6462.4 7853 6352.4 TRUE FALSE FALSE 8110.469166 7423.396786 7221.677142 7277.163915 7087.170237 8408.653071 7805.113893 8432.756011 6991.545547 6573.145427 1.233879465 1.129352282 1.098663832 1.107105266 1.078200736 1.279243425 1.187424496 1.282910306 1.063652953 1 12.68236819 -9.439509591 1.073327505 0.99612656 1.174960761 0.378913621 0.071651867 0.405244536 0.805509349 0.056588207 0.01294828 3.63E-10 9.439509591 0.178834201 LALAGIGQPVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 LALAGIGQPVKK 12 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 0 1 LALAGIGQPVK(1)K 138.98 6.48E-12 0 435.35 423.63 394.64 415.68 573.58 798.23 485.97 194.04 538.39 277.49 FALSE TRUE FALSE 400.8915881 460.2466895 409.2657056 413.9600263 566.7404331 632.6681001 499.6050103 253.2019027 479.329964 287.1327568 1.39618897 1.60290555 1.425353589 1.441702545 1.97379233 2.203399247 1.73997915 0.88182869 1.669367053 1 8.165574116 -8.006588227 0.505669511 1.005811593 1.691140813 0 0.387298785 0.709715678 0.43203014 0.197989717 0.120364016 9.85E-09 8.006588227 0.68532922 LALEDSENTASTNCDS(ph)SSEGLEKDTATQR ddPTM_HeLa_Curcumin_4h_R1 1 LALEDSENTASTNCDSSSEGLEKDTATQR 29 1 Q49AR2 Q49AR2 C5orf22 UPF0489 protein C5orf22 1 0 LALEDS(0.001)ENT(0.081)AS(0.055)T(0.02)NCDS(0.653)S(0.153)S(0.037)EGLEKDTATQR 93.392 5.51E-08 11573000 1857.3 1355.6 1371 1634.4 1672 2171.3 1404.2 1150.9 1914.6 1776.6 TRUE FALSE FALSE 1710.292745 1472.772024 1421.810466 1627.637286 1652.062492 1720.947904 1443.598073 1501.804112 1704.57317 1838.336718 0.930347922 0.801143778 0.77342222 0.885385833 0.898672412 0.936144009 0.785274025 0.816936363 0.927236645 1 10.84418533 -7.576733357 2.255905166 0.974575447 0.845538 0.459730001 0.053519486 0.166600245 1.739421161 0.010814259 0.011427586 2.65E-08 7.576733357 -0.129037447 LALPGHAESYNPPPEYLLS(ph)EEER ddPTM_HeLa_Curcumin_4h_R1 1 LALPGHAESYNPPPEYLLSEEER 23 0 Q14137;Q14137-2 Q14137 BOP1 Ribosome biogenesis protein BOP1 1 0 LALPGHAESYNPPPEYLLS(1)EEER 151.16 8.79E-07 5767100 1252.8 1723.2 1161.7 1110.2 1501.2 2240.9 1140.6 1166.4 1405.1 1289.4 TRUE FALSE FALSE 1153.639558 1872.14573 1204.753624 1105.606287 1483.29917 1776.11208 1172.602166 1522.029991 1250.964045 1334.206554 0.864663387 1.403190326 0.902973846 0.828662011 1.111746278 1.331212228 0.878876035 1.140775381 0.937608979 1 10.38176632 LALS(ph)PLSLGK ddPTM_HeLa_Curcumin_4h_R1 2 LALSPLSLGK 10 0 P49454 P49454 CENPF Centromere protein F 1 0 LALS(0.994)PLS(0.006)LGK;LALS(0.977)PLS(0.023)LGK ; 147.62 0.00097019 243790000 12757.6 10474.7 11837.8 11040.6 12546.5 15166.9 14837.1 3378.5 10381.6 7767.4 TRUE FALSE FALSE 11747.8225 11380.08639 12276.51928 10994.91692 12396.89118 12021.11397 15253.38909 4408.589097 9242.764453 8037.316572 1.461659796 1.415906204 1.527440057 1.367983558 1.542416685 1.495662622 1.897821115 0.54851505 1.149981386 1 12.97249819 -9.183618395 0.773277273 0.978515116 1.436849217 0.132756905 0.324072405 0.871280272 0.873568591 0.24699213 0.05878101 6.55E-10 9.183618395 0.458334101 LANQDEGPEDEEDEVPKKQNS(ph)PVAPTAQPK ddPTM_HeLa_Curcumin_4h_R1 2 LANQDEGPEDEEDEVPKKQNSPVAPTAQPK 30 2 Q6P1N0;Q6P1N0-2 Q6P1N0 CC2D1A Coiled-coil and C2 domain-containing protein 1A 1 0 LANQDEGPEDEEDEVPKKQNS(0.639)PVAPT(0.361)AQPK;LANQDEGPEDEEDEVPKKQNS(0.988)PVAPT(0.012)AQPK ; 62.831 0.00031617 18369000 3630.4 2517.2 2849.8 3251.5 2605.2 3798.2 2683 2380.7 4280.3 3585.1 TRUE FALSE FALSE 3343.050009 2734.775552 2955.416095 3238.046155 2574.134692 3010.410505 2758.277759 3106.564471 3810.761799 3709.681958 0.9011689 0.737199464 0.796676407 0.872863548 0.693896329 0.811500969 0.743534834 0.837420702 1.027247576 1 11.85707979 -7.736741534 0.915861399 0.979868363 0.780813202 0.710327915 0.056281782 0.184599801 0.327811304 0.013916279 0.012649898 1.83E-08 7.736741534 -0.199055161 LAPDYDALDVANK ddPTM_HeLa_Curcumin_4h_R1 2 LAPDYDALDVANK 13 0 K7EMA7;H7BY10;K7EJV9;K7ERT8;A8MUS3;P62750 K7EMA7 RPL23A 60S ribosomal protein L23a 0 0 ; ; 192.44 2.76E-13 2731730 1492.11 1601.17 1392.93 1492.9 1418.057 1657.32 1597.56 1328.1 1817.24 1618.4 FALSE FALSE TRUE 1374.007919 1739.568 1444.553211 1486.722775 1401.147596 1313.57315 1642.383234 1733.031576 1617.893319 1674.63928 0.82047993 1.038771765 0.862605594 0.887786877 0.836686213 0.784391699 0.980738511 1.034868582 0.966114517 1 10.70963465 -9.631592675 1.450847359 1.000015394 0.891929013 0.097778178 0.08446148 0.590627464 2.233138375 0.061423845 0.013982081 2.34E-10 9.631592675 -0.108086381 LAPEFAK ddPTM_HeLa_Curcumin_4h_R1 1 LAPEFAK 7 0 P30041 P30041 PRDX6 Peroxiredoxin-6 0 0 105.39 0.016924 8312900 8344.5 5723.6 7123.5 6721.2 7327.9 8927.1 7030.1 7519.6 7593.2 7407 FALSE FALSE TRUE 7684.02402 6218.32248 7387.503176 6693.389455 7240.519579 7075.518831 7227.345685 9812.291424 6760.244957 7664.392699 1.002561367 0.811326184 0.96387326 0.873309826 0.944695798 0.923167576 0.942976955 1.280243825 0.882032696 1 12.90395577 -4.258909043 24.8114408 0.965675432 1.280243949 0.688817788 0.066824761 100.2212698 982661.538 0.009604576 0.0872914 5.51E-05 4.258909043 0.314568517 LAPEYEAAATR ddPTM_HeLa_Curcumin_4h_R1 1 LAPEYEAAATR 11 0 H7BZJ3;P30101 H7BZJ3;P30101 PDIA3 Protein disulfide-isomerase A3 0 0 112.71 0.0037079 7202300 1276.3 1088.5 1118.2 1154.8 1382.5 1397.4 1162.9 869.03 1091.4 1311.8 FALSE FALSE TRUE 1175.279508 1182.58509 1159.641476 1150.021744 1366.01459 1107.563488 1195.527844 1133.993246 971.6761505 1357.384952 0.865840973 0.871223073 0.854320268 0.847233308 1.006357547 0.815953858 0.880758139 0.835424943 0.715844204 1 10.40661421 -9.199583546 0.749584423 1.007994517 0.872571716 0 0.100982727 0.509572475 0.470267973 0.042281329 0.009569495 6.32E-10 9.199583546 -0.135422801 LAPGGHVGR ddPTM_HeLa_Curcumin_4h_R1 4 LAPGGHVGR 9 0 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 0 ;;; ;;; 161.9 0.00046271 39816200 23450.2 17133.9 20881 17742.6 20864.8 23428 18569.2 19767 19042.6 18361.9 FALSE FALSE TRUE 21594.09193 18614.87797 21654.86823 17669.18582 20616.00089 18568.76871 19090.20178 25793.8673 16953.67442 18999.97466 1.13653267 0.979731726 1.139731427 0.929958389 1.085054125 0.97730492 1.004748802 1.357573774 0.892299844 1 14.21370987 -4.256398789 24.65454898 1.048649279 1.357573931 0.576763554 0.083672631 222.9282356 1090342.928 0.009914381 0.110514011 5.54E-05 4.256398789 0.308924652 LAPLGPLNPSYKSS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 2 LAPLGPLNPSYKSSPTR 17 1 Q96T17;Q96T17-2 Q96T17 MAP7D2 MAP7 domain-containing protein 2 1 0 LAPLGPLNPS(0.046)Y(0.002)KS(0.199)S(0.554)PT(0.199)R;LAPLGPLNPS(0.051)YKS(0.078)S(0.793)PT(0.078)R ; 130.64 0.0029536 95763000 3599.9 2860.3 2947.8 3156.5 2226.45 3713.7 2756.3 2211.2 4293.5 3496.5 TRUE FALSE FALSE 3314.964116 3107.531587 3057.048061 3143.439239 2199.901038 2943.436758 2833.63436 2885.384701 3822.513792 3618.003115 0.916241366 0.858907936 0.844954513 0.868832652 0.608042881 0.813552854 0.783203958 0.797507523 1.056525843 1 11.82097793 -7.11003246 0.612833646 0.984075074 0.759152423 0.673610416 0.066835608 0.300913948 0.244675658 0.018153194 0.02421368 7.76E-08 7.11003246 -0.224922651 LAPVPS(ph)PEPQKPAPVS(ph)PESVK ddPTM_HeLa_Curcumin_4h_R1 1 LAPVPSPEPQKPAPVSPESVK 21 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 2 0 LAPVPS(1)PEPQKPAPVS(0.833)PES(0.167)VK 75.193 0.0014774 29807000 1666.1 1422.3 1444.5 1807.2 1618.7 1940.8 1654.7 1391.6 2071.7 1677 TRUE FALSE FALSE 1534.226427 1545.237274 1498.034441 1799.722285 1599.39806 1538.256203 1701.126429 1815.892434 1844.439693 1735.275625 0.884139905 0.890485207 0.863283284 1.037139149 0.92169684 0.886462174 0.980320592 1.046457639 1.062908777 1 10.76094912 -6.261614062 24.99990621 0.933325206 0.966928262 0.045837253 0.070959341 43.10863167 6169641.935 0.010525978 0.016704584 5.48E-07 6.261614062 0.033603056 LAPVPS(ph)PEPQKPAPVSPESVK ddPTM_HeLa_Curcumin_4h_R1 2 LAPVPSPEPQKPAPVSPESVK 21 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 LAPVPS(1)PEPQKPAPVSPESVK;LAPVPS(0.999)PEPQKPAPVS(0.001)PESVK ; 90.442 0.00020571 360310000 8886.2 6256.7 7774.6 7612.9 7115.2 7737 6190.6 4729.9 8262.2 7045.8 TRUE FALSE FALSE 8182.847893 6797.501269 8062.733515 7581.399837 7030.355887 6132.258986 6364.291575 6172.024736 7355.857331 7290.641026 1.122377012 0.932359891 1.105901866 1.039881104 0.964298731 0.841113829 0.872939917 0.846568184 1.008945209 1 12.83182995 -5.502792984 2.490005968 1.051839685 0.854387014 0.697234899 0.052658643 0.123988329 1.524780283 0.008717992 0.021106396 3.14E-06 5.502792984 -0.197452671 LAPVPSPEPQKPAPVS(ph)PESVK ddPTM_HeLa_Curcumin_4h_R1 1 LAPVPSPEPQKPAPVSPESVK 21 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 LAPVPS(0.013)PEPQKPAPVS(0.938)PES(0.05)VK 57.482 0.0066045 139840000 1172.2 1074.8 748.83 1340 1208.6 1424.4 1177.8 1506.8 938.42 1042.8 TRUE FALSE FALSE 1079.419133 1167.700923 776.5822985 1334.455435 1194.188234 1128.963384 1210.845898 1966.216384 835.4776738 1079.037222 1.000353937 1.08216927 0.719699267 1.236709362 1.106716441 1.046269174 1.122153966 1.822195141 0.77428068 1 10.07552892 LAQYES(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 LAQYESK 7 0 P24534 P24534 EEF1B2 Elongation factor 1-beta 1 0 LAQYES(1)K 119.22 0.012445 4260000 1199.2 1152.1 1140 1080.5 1253.1 1746.8 1265.4 1263.5 1215.2 1305.8 TRUE FALSE FALSE 1104.282055 1251.68239 1182.249403 1076.029177 1238.157601 1384.49399 1300.903718 1648.735334 1081.8956 1351.176453 0.817274496 0.926364864 0.874977802 0.796364661 0.916355224 1.024658169 0.962793361 1.220222074 0.800706376 1 10.40000038 -2.759834464 0.902038838 0.903332646 5.33395979 0.663487191 0.07093235 14.69505773 0.988993885 0.01260389 114.8651573 0.001738463 2.759834464 4.430627143 LARLRQLMQRS(ph)LSES(ph)DTDS(ph)NNS(ph)EDPK ddPTM_HeLa_Curcumin_4h_R1 1 LARLRQLMQRSLSESDTDSNNSEDPK 26 3 D6R9G8;Q9Y6H5-5;Q9Y6H5-2;Q9Y6H5-4;Q9Y6H5;Q9Y6H5-3 D6R9G8 SNCAIP Synphilin-1 4 0 LARLRQLMQRS(0.704)LS(0.309)ES(0.523)DT(0.523)DS(0.948)NNS(0.993)EDPK 42.319 0.01403 3512800 1255 990.91 1115.1 977.41 1104.1 1750.3 897.43 1376 1061.6 1132.8 TRUE FALSE FALSE 1155.665426 1076.559845 1156.426587 973.3657364 1090.934329 1387.26805 922.6094705 1795.536066 945.145136 1172.164716 0.985924086 0.918437341 0.98657345 0.830400134 0.930700536 1.183509477 0.787098825 1.531812075 0.806324507 1 10.1949596 -4.24914902 24.84223689 0.975106897 1.53181245 0.694716411 0.115869655 653.6016265 1321085.638 0.012780452 0.294215876 5.63E-05 4.24914902 0.556705553 LAS(ph)ART(ph)LYEVSLQES(ph)IRY(ph)APGDAVEK ddPTM_HeLa_Curcumin_4h_R1 1 LASARTLYEVSLQESIRYAPGDAVEK 26 2 A0A087WV29;Q9H0A0-2;Q9H0A0 A0A087WV29 NAT10 N-acetyltransferase 10 4 0 LAS(0.796)ART(0.796)LY(0.313)EVS(0.182)LQES(0.937)IRY(0.976)APGDAVEK 42.322 0.0092199 0 277.27 476.42 453.01 426.42 502.08 537.03 524.07 430.48 527.71 471.45 TRUE FALSE FALSE 255.3237869 517.5996219 469.7989491 424.655587 496.0930239 425.6439244 538.7739937 561.7313703 469.8215333 487.8328524 0.523383748 1.061018378 0.963032618 0.870494033 1.016932381 0.872520008 1.104423351 1.151483275 0.963078913 1 8.930243107 -5.105803669 0.584281022 0.798425675 1.196574967 0.116002083 0.156861643 1.90302687 0.768521586 0.041203894 0.426112791 7.84E-06 5.105803669 0.398149292 RPS(ph)TSQTVSTPAPVPVIESTEAIEAK ddPTM_HeLa_Curcumin_4h_R1 1 RPSTSQTVSTPAPVPVIESTEAIEAK 26 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 0 RPS(0.198)T(0.198)S(0.198)QT(0.198)VS(0.198)T(0.009)PAPVPVIESTEAIEAK 115.92 5.93E-09 10569000 642.76 575.7 551.84 604.74 787.7 696.18 953.5 2423.1 815.71 667.93 TRUE FALSE FALSE 591.8848678 625.4609427 572.2916758 602.2377461 778.307192 551.7844204 980.2526438 3161.892035 726.2286538 691.1405178 0.856388611 0.904969289 0.828039539 0.871368022 1.126120046 0.798367924 1.418311644 4.574890278 1.050768455 1 9.432835249 -4.257860448 3.221592672 0.925462694 5.114907671 0.991588246 0.100107831 0.019486063 0.314579533 0.013242874 0.204580504 5.52E-05 4.257860448 4.189444977 up LAS(ph)PMKPVPGTPPSSK ddPTM_HeLa_Curcumin_4h_R1 1 LASPMKPVPGTPPSSK 16 1 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 0 LAS(1)PMKPVPGTPPSSK 81.316 0.0051232 49109000 2093.2 1996.1 1955.1 2103.4 2138.2 2193.4 1748.2 1695.3 2196.3 1785.6 TRUE FALSE FALSE 1927.521011 2168.63399 2027.557726 2094.696688 2112.703362 1738.464115 1797.249787 2212.189166 1955.371385 1847.649467 1.043228732 1.173725876 1.097371424 1.133708923 1.143454643 0.940905808 0.972722272 1.197299166 1.05830214 1 10.85147536 -7.585246586 3.652736673 1.017198201 1.08822117 0.099115732 0.078659719 0.316121036 9.000948808 0.014554072 0.015441636 2.60E-08 7.585246586 0.071022969 LAS(ph)SVLR ddPTM_HeLa_Curcumin_4h_R1 1 LASSVLR 7 0 J3QR09;J3KTE4;P84098 J3QR09 RPL19 Ribosomal protein L19;60S ribosomal protein L19 1 0 LAS(0.841)S(0.159)VLR 106.68 0.016941 2878300 2304.7 2080.9 1676.4 1901.2 1851.9 2577.9 2136.5 1542.2 2475.1 1967.4 TRUE FALSE FALSE 2122.280563 2260.763724 1738.528859 1893.333338 1829.817302 2043.214481 2196.44444 2012.409681 2203.587722 2035.767004 1.042496788 1.110521842 0.853992061 0.930034397 0.898834345 1.003658315 1.078927223 0.988526524 1.082436113 1 10.99135674 -10.64934916 11.48706027 0.889121613 1.003907828 0 0.080304782 304090.2214 615781.2662 871920.0271 0.011057403 2.24E-11 10.64934916 0.114786215 ALVHQLS(ph)NESR ddPTM_HeLa_Curcumin_4h_R1 2 ALVHQLSNESR 11 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 0 ALVHQLS(0.998)NES(0.002)R;ALVHQLS(0.991)NES(0.009)R ; 81.789 0.012319 11498700 2180.3 1716.67 2177.69 2342.6 1983.96 2687.8 2291.9 5679.8 2024.1 1750.38 TRUE FALSE FALSE 2007.726954 1865.051305 2258.397107 2332.906942 1960.302573 2130.319982 2356.204546 7411.544873 1802.061294 1811.205575 1.108503078 1.029729221 1.246902692 1.288040946 1.082319202 1.17618895 1.300903983 4.092050608 0.994951274 1 10.82273459 -4.257810854 4.16220889 1.093708136 4.346665835 0.988531612 0.09566409 0.01806737 0.687335394 0.015154146 0.175559444 5.52E-05 4.257810854 3.252957698 up NMTVEQLLTGSPTS(ph)PTVEPEKPTR ddPTM_HeLa_Curcumin_4h_R1 1 NMTVEQLLTGSPTSPTVEPEKPTR 24 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 0 NMTVEQLLT(0.117)GS(0.018)PT(0.32)S(0.424)PT(0.121)VEPEKPTR 100.06 3.52E-05 12178000 1439 1246.5 1388 1344.4 1590.5 1928.3 1906 6465.5 1434 1436.1 TRUE FALSE FALSE 1325.101632 1354.241906 1439.440501 1338.837229 1571.534326 1528.348844 1959.47723 8436.801186 1276.693788 1486.004368 0.891721222 0.91133104 0.968665054 0.900964531 1.057557003 1.028495526 1.318621447 5.677507663 0.85914538 1 10.53722264 -4.257805302 4.03605958 0.959526619 6.109192632 0.998099006 0.061515232 0.00817563 0.27858998 0.010296151 0.122974537 5.52E-05 4.257805302 5.149666013 up LAS(ph)Y(ph)Y(ph)KY(ph)WEK ddPTM_HeLa_Curcumin_4h_R1 1 LASYYKYWEK 10 1 A0A087WV07;A0A1C7CYW8;A0A669KB38;Q8IVF4-2;Q8IVF4 A0A087WV07 DNAH10 "Dynein heavy chain 10, axonemal" 4 0 LAS(1)Y(1)Y(1)KY(1)WEK 46.73 0.0094583 0 555.53 299.92 392.02 539.45 556.25 263.2 123.25 203.08 594.76 416.06 TRUE FALSE FALSE 511.5592143 325.8437484 406.5486061 537.2178988 549.617082 208.6093531 126.7080633 264.9981571 529.516316 430.518054 1.188241026 0.756864306 0.944324175 1.247840581 1.276641193 0.484554251 0.29431533 0.615533204 1.229951476 1 8.749929929 -5.245785658 21.89536156 1.07719956 0.447751751 0.7437091 0.168474565 59.93420977 83830.45369 0.023750674 0.060199583 5.68E-06 5.245785658 -0.62944781 LASDS(ph)DAESDSR ddPTM_HeLa_Curcumin_4h_R1 2 LASDSDAESDSR 12 0 A0A0A0MRB5;Q8WXG6-6;Q8WXG6-8;Q8WXG6-5;Q8WXG6-4;Q8WXG6-7;Q8WXG6-3;Q8WXG6-2;Q8WXG6 A0A0A0MRB5 MADD MAP kinase-activating death domain protein 1 0 LASDS(1)DAESDSR;LAS(0.001)DS(0.999)DAESDSR ; 251.91 2.11E-35 189789000 5816.9 4221.4 4630.3 4865.4 4469.8 4827.6 3108 2267 5377.9 3809.4 TRUE FALSE FALSE 5356.486227 4586.279006 4801.902991 4845.268264 4416.500554 3826.301342 3195.202115 2958.197864 4787.957825 3941.776366 1.358901604 1.163505633 1.21820787 1.229209324 1.120434074 0.970704826 0.810599541 0.750473286 1.214670083 1 11.94463021 -4.991900046 1.668955725 1.180927591 0.75097643 0.794918306 0.08414785 0.214073452 1.093896654 0.019630213 0.093542787 1.02E-05 4.991900046 -0.429951161 LASEEPPDDEEALATIR ddPTM_HeLa_Curcumin_4h_R1 1 LASEEPPDDEEALATIR 17 0 Q9UBB4-2;Q9UBB4;B1AHE4 Q9UBB4-2 ATXN10 Ataxin-10 0 0 247.14 5.18E-30 3180600 1037.4 1081.7 936.12 945.46 959.88 1171.8 860.42 678.15 1087.4 859.24 FALSE FALSE TRUE 955.2886953 1175.197328 970.8134307 941.547937 948.4340579 928.7554711 884.5610695 884.9148132 968.1149405 889.098526 1.074446383 1.321785262 1.091907592 1.058991675 1.066736734 1.044603544 0.994896565 0.995294433 1.088872506 1 9.796199491 -4.869191382 2.733984367 1.065916485 0.992687553 0.121406512 0.084364713 0.566055965 8.339222998 0.013491853 0.053326983 1.35E-05 4.869191382 -0.073228933 LASLGDT(ph)ASPLVK ddPTM_HeLa_Curcumin_4h_R1 1 LASLGDTASPLVK 13 0 Q6P4F7-3;Q6P4F7 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 0 LASLGDT(0.658)AS(0.342)PLVK 222.81 1.26E-13 33131000 2089.2 1932.1 1665.6 1725.2 1876.8 3227.9 2294.5 995.94 2154.8 1181 TRUE FALSE FALSE 1923.837615 2099.102115 1727.328601 1718.06158 1854.420386 2558.397154 2358.877495 1299.597521 1918.423831 1222.039662 1.574284105 1.717703754 1.413479983 1.405896742 1.517479705 2.093546743 1.930278998 1.06346591 1.569853983 1 10.25507539 -9.380740413 0.442722572 0.803437878 1.640605097 0 0.326183932 1.653101594 0.400905393 0.63932873 0.083059022 4.16E-10 9.380740413 0.837167219 LASRPQGGRLMS(ph)S(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 LASRPQGGRLMSSR 14 2 Q52M75 Q52M75 LINC01554 Putative uncharacterized protein encoded by LINC01554 2 0 LASRPQGGRLMS(1)S(1)R 75.445 0.01838 53001000 5417.4 4943.7 5253.5 5457.5 5930.6 6787.6 5583.3 4463.3 4835.1 4637.3 TRUE FALSE FALSE 4988.607074 5371.011399 5448.199331 5434.918311 5859.881468 5379.775248 5739.952371 5824.139623 4304.701627 4798.44583 1.039629757 1.119323129 1.135409156 1.132641381 1.221204047 1.121149522 1.196210726 1.213755418 0.897103308 1 12.22835149 -6.993719951 0.697477712 1.006496987 1.188990512 0.781814878 0.045348622 0.14786293 0.148813673 0.007034599 0.010079478 1.01E-07 6.993719951 0.182493524 LASS(ph)VLR ddPTM_HeLa_Curcumin_4h_R1 2 LASSVLR 7 0 J3QR09;J3KTE4;P84098 J3QR09 RPL19 Ribosomal protein L19;60S ribosomal protein L19 1 0 LAS(0.041)S(0.959)VLR;LAS(0.039)S(0.961)VLR ; 120.87 0.01159 17149200 8592.7 6797 7993.3 8449.7 8177.6 10688.7 9562.4 7008.2 9087.8 8178.1 TRUE FALSE FALSE 7912.578728 7384.502393 8289.53873 8414.73738 8080.087461 8471.743134 9830.695208 9144.967918 8090.891077 8462.288366 0.935040073 0.872636582 0.979585943 0.994380836 0.954834805 1.001117283 1.161706477 1.080673161 0.956111483 1 13.04683213 -4.889615803 4.822241609 0.963583122 1.11989731 0.73264356 0.039073691 0.085524659 3.229873953 0.006038738 0.019220506 1.29E-05 4.889615803 0.156314188 DSSPSSSPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 DSSPSSSPSPK 11 0 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 1 0 DSSPS(0.001)S(0.006)S(0.125)PS(0.868)PK 140.45 0.0013477 6431600 2682.5 2855.5 3163.7 2653.1 3079.6 3651.2 2642.9 5232.9 2354.2 1977.2 TRUE FALSE FALSE 2470.177294 3102.316696 3280.949505 2642.122175 3042.877781 2893.899962 2717.052661 6828.387121 2095.95015 2045.907553 1.207374835 1.516352336 1.603664594 1.291418164 1.487299745 1.414482271 1.328042735 3.337583417 1.024459853 1 10.99852524 -4.257711315 4.608532028 1.228286483 3.475335888 0.894633892 0.205952048 0.051185708 2.84791382 0.035023136 0.37119425 5.52E-05 4.257711315 2.247049406 up LASVLPEVK(ac)PK ddPTM_HeLa_Curcumin_4h_R1 1 LASVLPEVKPK 11 1 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 0 1 LASVLPEVK(1)PK 119.22 0.0021657 1201800 1205.3 1619.7 1694.4 1395.7 1700 1488.6 1277.1 617.2 1438.4 1165.2 FALSE TRUE FALSE 1109.899233 1759.699651 1757.195955 1389.924963 1679.72861 1179.84758 1312.931989 805.3814388 1280.611119 1205.690613 0.920550613 1.45949519 1.457418624 1.152804001 1.393167195 0.978565784 1.088946015 0.667983502 1.06213908 1 10.23564404 PSVS(ph)ENLY(ph)PPS(ph)RK ddPTM_HeLa_Curcumin_4h_R1 1 PSVSENLYPPSRK 13 1 Q76M96;Q76M96-2 Q76M96 CCDC80 Coiled-coil domain-containing protein 80 3 0 PS(0.002)VS(0.998)ENLY(1)PPS(1)RK 67.095 0.011713 14689000 2236.5 1727 1720.3 1907.4 1997.7 2862.5 2905.7 8103.1 2420.8 2645.1 TRUE FALSE FALSE 2059.478665 1876.274185 1784.055831 1899.507684 1973.878732 2268.785233 2987.226122 10573.69789 2155.244297 2737.017028 0.752453728 0.685517907 0.651824893 0.694006528 0.721178828 0.82892624 1.091416711 3.863219622 0.78744278 1 11.41838869 -4.2576377 3.834603062 0.824586529 4.176901686 0.986651558 0.107254202 0.027454856 0.782360643 0.020542734 0.259279373 5.53E-05 4.2576377 3.352315156 up LATNAAVTVLR ddPTM_HeLa_Curcumin_4h_R1 2 LATNAAVTVLR 11 0 P50990-2;P50990;P50990-3;H7C2U0 P50990-2 CCT8 T-complex protein 1 subunit theta 0 0 ; ; 145.99 1.57E-05 8511000 1983.61 1620.58 1947.23 1928.74 1731.88 2604.47 1964.48 2228.71 1897.87 1776.75 FALSE FALSE TRUE 1826.605175 1760.655714 2019.396057 1920.759385 1711.228462 2064.273564 2019.598022 2908.233419 1689.678409 1838.49193 0.993534508 0.957663009 1.098398107 1.044747248 0.930778337 1.122808063 1.098507961 1.581858137 0.919056745 1 10.84430713 LATQLTGPVMPVR ddPTM_HeLa_Curcumin_4h_R1 2 LATQLTGPVMPVR 13 0 P26373;P26373-2 P26373 RPL13 60S ribosomal protein L13 0 0 ; ; 194.48 2.15E-13 7360800 1882.32 1306.47 1464.84 1463.52 1687.01 1950.91 1369.3 1513.83 1526.54 1263.5 FALSE FALSE TRUE 1733.332386 1419.395445 1519.128259 1457.464342 1666.893508 1546.269275 1407.718873 1975.389798 1359.082381 1307.406531 1.325779201 1.085657301 1.16194024 1.114775173 1.274961894 1.182699672 1.076726205 1.510922388 1.039525464 1 10.35249209 -9.536160159 1.274702245 0.999059824 1.218036167 0.285977803 0.124186826 0.447034781 1.29184108 0.085383809 0.019983879 2.91E-10 9.536160159 0.218976342 LATQSNEITIPVTFESR ddPTM_HeLa_Curcumin_4h_R1 3 LATQSNEITIPVTFESR 17 0 P04792;C9J3N8 P04792 HSPB1 Heat shock protein beta-1 0 0 ;; ;; 316.1 4.57E-154 32894700 1761.5 1600.73 1892.18 1777.41 1662.84 2591.4 1940.84 1492.13 1926.1 1566.29 FALSE FALSE TRUE 1622.075416 1739.089968 1962.305855 1770.055548 1643.011719 2053.914429 1995.294747 1947.073568 1714.811649 1620.718461 1.000837255 1.073036441 1.210762944 1.092142523 1.01375517 1.267286379 1.23111743 1.201364466 1.058056467 1 10.66241778 -5.811039594 0.397795686 0.98743563 1.276763702 0.481321853 0.070320548 1.000739061 0.243919369 0.024816247 0.118277721 1.55E-06 5.811039594 0.289328071 LAVEALSS(ph)LDGDLAGR ddPTM_HeLa_Curcumin_4h_R1 2 LAVEALSSLDGDLAGR 16 0 P12277;G3V4N7 P12277 CKB Creatine kinase B-type 1 0 LAVEALS(0.139)S(0.861)LDGDLAGR;LAVEALS(0.228)S(0.772)LDGDLAGR ; 225.31 1.21E-21 4535900 2105.39 2341.6 2075.37 1811.11 1959.3 2984.4 2243.4 1934.41 2586.4 2327.3 TRUE FALSE FALSE 1938.74616 2543.99747 2152.285038 1803.616107 1935.936627 2365.401799 2306.343766 2524.202704 2302.678391 2408.173502 0.805069136 1.056401239 0.893741683 0.748956047 0.80390247 0.982238945 0.957714951 1.048181413 0.956192894 1 11.23372362 -5.03665813 22.64555901 0.897879404 0.994705508 0.206642566 0.091009297 262.8774206 162393.0362 0.014828156 0.037827997 9.19E-06 5.03665813 0.096826104 LAVLSSS(ph)LTHWK ddPTM_HeLa_Curcumin_4h_R1 2 LAVLSSSLTHWK 12 0 F5GX19;F5H3Y3;Q6IAA8 F5GX19 LAMTOR1 Ragulator complex protein LAMTOR1 1 0 LAVLS(0.035)S(0.212)S(0.711)LT(0.042)HWK;LAVLS(0.024)S(0.127)S(0.809)LT(0.04)HWK ; 98.592 0.0028216 5348400 5260.5 5410.9 4887.8 4987.7 6283.4 12797.1 4628.5 3212.4 8569.1 6717.3 TRUE FALSE FALSE 4844.125874 5878.594085 5068.946168 4967.062219 6208.474559 10142.83721 4758.363253 4191.845972 7629.091169 6950.725675 0.69692376 0.845752567 0.729268627 0.714610596 0.893212428 1.459248671 0.684585103 0.603080335 1.097596355 1 12.76294789 -4.542690225 24.99973744 0.875820396 0.623455463 0.185122181 0.220473453 278.4511884 351372.2592 0.030736796 0.115034312 2.87E-05 4.542690225 -0.252364933 LAVNMVPFPR ddPTM_HeLa_Curcumin_4h_R1 2 LAVNMVPFPR 10 0 Q5JP53;P07437;Q5ST81;A0A075B736;Q5SQY0;A6NNZ2;CON__ENSEMBL:ENSBTAP00000025008;Q9H4B7;P04350;P68371;Q3ZCM7;Q9BVA1;Q13885;A0A0B4J269;Q13509;Q13509-2;Q9BUF5;K7ESM5 Q5JP53;P04350;P68371;Q9BVA1;A0A0B4J269;Q9BUF5 TUBB;TUBB8;TUBB1;TUBB4A;TUBB4B;TUBB2B;TUBB2A;TUBB3;TUBB6 Tubulin beta chain;Tubulin beta-8 chain-like protein LOC260334;Tubulin beta-1 chain;Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-8 chain;Tubulin beta-2B chain;Tubulin beta-2A chain;Tubulin beta-3 chain;Tubulin beta-6 chain 0 0 ; ; 109.86 0.0054012 2190100 672.72 248.49 665.94 359.74 621.17 919.17 702.73 519.19 517.65 766.71 FALSE FALSE TRUE 619.4735021 269.9683684 690.6203222 358.2514912 613.7629534 728.5237808 722.4467125 677.4886409 460.8650901 793.3531154 0.780829482 0.340287777 0.870508111 0.45156625 0.773631491 0.918284389 0.91062441 0.853955985 0.580907897 1 9.631819331 -8.650732109 1.068946588 0.97472043 0.73848589 0 0.221972624 0.526221025 1.211200306 0.068298867 0.036630796 2.23E-09 8.650732109 -0.23623454 LAVPTEVSTEVPEMDT(ph)ST ddPTM_HeLa_Curcumin_4h_R1 2 LAVPTEVSTEVPEMDTST 18 0 O00488 O00488 ZNF593 Zinc finger protein 593 1 0 LAVPTEVSTEVPEMDT(0.521)S(0.24)T(0.24);LAVPTEVSTEVPEMDT(0.333)S(0.333)T(0.333) ; 196.84 8.11E-09 19080100 8701.7 7423.7 8309.2 8114.1 8216.5 10389 7098.4 6196.9 8420.1 8060.9 TRUE FALSE FALSE 8012.951263 8065.371549 8617.146262 8080.526004 8118.523604 8234.204292 7297.562 8086.306283 7496.436096 8341.015675 0.960668529 0.96695317 1.033105151 0.96877003 0.973325542 0.987194439 0.874900885 0.969463024 0.898743797 1 13.02600735 -4.792000391 24.99972017 0.982539876 0.922181917 0.189292824 0.039207102 120.8359294 98846.92308 0.003909041 0.011729138 1.61E-05 4.792000391 -0.060357959 LAVPTEVSTEVPEMDTS(ph)T ddPTM_HeLa_Curcumin_4h_R1 1 LAVPTEVSTEVPEMDTST 18 0 O00488 O00488 ZNF593 Zinc finger protein 593 1 0 LAVPTEVSTEVPEMDT(0.269)S(0.365)T(0.365) 93.258 0.0027035 7443100 3268.3 3054.9 3383.8 3584.7 3338.9 3804.7 3173.7 2998.6 3570.5 3301.8 TRUE FALSE FALSE 3009.610606 3318.951944 3509.206605 3569.867461 3299.085798 3015.562332 3262.74548 3912.859336 3178.825083 3416.537304 0.880894993 0.97143735 1.027123749 1.044878818 0.965622648 0.882637028 0.954986055 1.145270485 0.930423057 1 11.73831916 -7.002542772 24.8091113 0.94283019 0.996176754 0.149094556 0.069525778 176.7308073 1724340.472 0.012546248 0.016329527 9.94E-08 7.002542772 0.053346564 LAVYIDK ddPTM_HeLa_Curcumin_4h_R1 1 LAVYIDK 7 0 P20700;E9PBF6;A0A0D9SFE5;A0A0D9SFY5 P20700 LMNB1 Lamin-B1 0 0 105.39 0.016924 2103600 3068.6 1919.7 2464.2 1896.5 2611.1 2815.2 2379 1711 2296.1 2170.5 FALSE FALSE TRUE 2825.717072 2085.630314 2555.52542 1888.652786 2579.964338 2231.295786 2445.748337 2232.676024 2044.223575 2245.924713 1.258153069 0.928628774 1.137849993 0.840924353 1.148731443 0.993486457 1.088971648 0.994101009 0.910192386 1 11.13309385 -7.245715441 24.80602803 1.121905623 1.023386351 0 0.124653369 1173.640491 1851532.809 0.020139138 0.024618523 5.68E-08 7.245715441 -0.098519272 LAVYIDR ddPTM_HeLa_Curcumin_4h_R1 2 LAVYIDR 7 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 134.44 0.00622 29051000 7052.2 4882.8 6017.4 5506.3 5992.3 6883.4 5758.2 5595.2 5954.9 5616.4 FALSE FALSE TRUE 6494.010929 5304.847475 6240.410137 5483.51639 5920.845736 5455.705248 5919.759595 7301.150723 5301.662368 5811.569482 1.11742808 0.912808062 1.073790851 0.943551722 1.018803226 0.938766243 1.018616333 1.256313074 0.912259999 1 12.50471212 -4.259856356 24.24596885 1.028673912 1.256313186 0.488905119 0.072965671 60.47961172 926182.7399 0.009813937 0.082667836 5.50E-05 4.259856356 0.227639274 LCAGIMITAS(ph)HNPK ddPTM_HeLa_Curcumin_4h_R1 1 LCAGIMITASHNPK 14 0 Q96G03-2;Q96G03 Q96G03-2 PGM2 Phosphoglucomutase-2 1 0 LCAGIMIT(0.001)AS(0.999)HNPK 234.82 6.48E-21 47706000 2493.3 2188.2 2050.7 1875.7 2244.7 3060.7 2535.6 2226.8 2077.3 2132.9 TRUE FALSE FALSE 2295.952674 2377.338258 2126.700746 1867.93885 2217.933419 2425.876319 2606.742112 2905.741069 1849.425387 2207.018116 1.040296252 1.077172063 0.963608196 0.846363171 1.004945724 1.099164661 1.181114959 1.316591399 0.83797472 1 11.10788276 -4.634080571 1.627539341 1.006325063 1.327582664 0.659081206 0.080093084 0.221963761 0.899225806 0.009481853 0.089698108 2.32E-05 4.634080571 0.321257601 LCDDGPQLPT(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 LCDDGPQLPTSPR 13 0 O60504-2;O60504;H0YAZ3;H0YB51 O60504-2 SORBS3 Vinexin 1 0 LCDDGPQLPT(0.928)S(0.072)PR 231.07 4.33E-19 370190000 6085.7 5103.1 4698.2 4953.3 5507.3 5552.7 4422.9 2434.6 5570.1 4410.8 TRUE FALSE FALSE 5604.010423 5544.189225 4872.319425 4932.804557 5441.629044 4401.007428 4546.99467 3176.898332 4959.073966 4564.074972 1.227852403 1.214745432 1.067537114 1.080789555 1.192274246 0.964271502 0.996257664 0.696066202 1.086545247 1 12.15610677 -3.759734426 0.968334338 1.117206738 4.51E-10 0.729921182 0.077002536 2.282520163 0.839234898 0.015208801 3.362690458 0.000173886 3.759734426 -1.117206737 LCDDGPQLPTS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 LCDDGPQLPTSPR 13 0 O60504-2;O60504;H0YAZ3;H0YB51 O60504-2 SORBS3 Vinexin 1 0 LCDDGPQLPT(0.001)S(0.999)PR;LCDDGPQLPT(0.003)S(0.997)PR ; 230.69 1.58E-19 468630000 13054.7 12059.6 12853.9 12063.7 12741.8 13294.6 9969.6 5362.7 12787.5 11697.6 TRUE FALSE FALSE 12021.40672 13101.97809 13330.27684 12013.78361 12589.86236 10537.1501 10249.32014 6997.762543 11384.74324 12104.09073 0.99316892 1.082442158 1.101303447 0.992539124 1.040132848 0.87054454 0.84676498 0.57813203 0.940569886 1 13.56320709 -4.071310968 1.011862438 1.013543592 0.224368177 0.870685137 0.052084246 0.612732904 0.377694525 0.007570742 0.571407164 8.49E-05 4.071310968 -0.789175415 LCDFGSASHVADNDIT(ph)PYLVSR ddPTM_HeLa_Curcumin_4h_R1 1 LCDFGSASHVADNDITPYLVSR 22 0 Q13523;H0YDJ3 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 0 LCDFGSASHVADNDIT(0.758)PY(0.241)LVSR 167.9 1.23E-08 10373000 2832.9 2158.5 2319.9 1921.4 2938.5 5622.8 2825.9 2377.7 3948.2 2667 TRUE FALSE FALSE 2608.672976 2345.071122 2405.877535 1913.449756 2903.460307 4456.567898 2905.187148 3102.649784 3515.092338 2759.678051 0.945281633 0.849762573 0.871796452 0.693359776 1.052101097 1.614886887 1.052726838 1.124279618 1.273732759 1 11.43028425 -5.513146557 24.99667238 0.934536909 1.257949585 0.359386249 0.193941338 313.938833 806336.3667 0.02309025 0.048455889 3.07E-06 5.513146557 0.323412676 LCDFGSASHVADNDITPY(ph)LVSR ddPTM_HeLa_Curcumin_4h_R1 1 LCDFGSASHVADNDITPYLVSR 22 0 Q13523;H0YDJ3 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 0 LCDFGSASHVADNDIT(0.19)PY(0.442)LVS(0.368)R 86.539 0.0024706 18099000 882.35 844.65 804.34 745.68 868.89 1425.2 928.28 910.34 1137.4 876.26 TRUE FALSE FALSE 812.5110664 917.6577823 834.149548 742.5945737 858.5290542 1129.597455 954.3250385 1187.898475 1012.630066 906.7099698 0.896109113 1.012074217 0.919973945 0.818999017 0.946861822 1.245820044 1.052514112 1.31011957 1.116818056 1 9.824497338 -5.270813336 24.30218978 0.941821881 1.187787528 0.567750058 0.096567798 190.9499641 495042.9008 0.011279581 0.0255515 5.36E-06 5.270813336 0.245965647 LCDSYEIRPGK ddPTM_HeLa_Curcumin_4h_R1 1 LCDSYEIRPGK 11 1 O43390;B4DT28;O43390-4;O43390-3;O43390-2 O43390 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 0 86.344 0.014525 4619300 3875 2732.7 3042.2 3316.5 2761.9 4547.3 4067.2 3241.4 4100.2 3156 FALSE FALSE TRUE 3568.289661 2968.902411 3154.946608 3302.777202 2728.966146 3604.138721 4181.314686 4229.687938 3650.418318 3265.670765 1.092666689 0.90912484 0.966094513 1.011362577 0.835652563 1.103644237 1.28038464 1.295197294 1.117815781 1 11.67316363 -4.857612638 3.788956286 1.01263922 1.291009733 0.682011671 0.079361709 0.099593881 2.685973599 0.011372349 0.039257034 1.39E-05 4.857612638 0.278370512 LCLS(ph)TVDLEVK ddPTM_HeLa_Curcumin_4h_R1 1 LCLSTVDLEVK 11 0 Q8N370-4;Q8N370-2;Q8N370;Q8N370-3 Q8N370-4 SLC43A2 Large neutral amino acids transporter small subunit 4 1 0 LCLS(0.91)T(0.09)VDLEVK 124.86 0.0021691 0 552.79 853.05 623.21 1206.7 618.95 1730.5 659.32 415.69 1510.7 991.97 TRUE FALSE FALSE 509.0360882 926.7838409 646.3067108 1201.706995 611.5694255 1371.574793 677.8187447 542.4319674 1344.97999 1026.440884 0.495923434 0.9029101 0.629657997 1.170751296 0.595815536 1.336243339 0.660358288 0.528459043 1.310333611 1 10.00343482 LCNLEEGS(ph)PGSGTYTR ddPTM_HeLa_Curcumin_4h_R1 1 LCNLEEGSPGSGTYTR 16 0 R4GNH9;R4GMQ7;B1AMU7;B1AMU3;B1AMU4;Q9Y3B2 R4GNH9 EXOSC1 Exosome complex component CSL4 1 0 LCNLEEGS(0.966)PGS(0.034)GTYTR 195.45 2.12E-07 12726000 1771.4 1563.3 1178.4 1573.6 1346.8 2237.8 1767.5 1026.9 1446.9 1197.7 TRUE FALSE FALSE 1631.191821 1698.424686 1222.072541 1567.08886 1330.74029 1773.655055 1817.091293 1339.997083 1288.17869 1239.319986 1.316199076 1.37044888 0.986083138 1.264474775 1.073766505 1.431151821 1.466200266 1.081235757 1.039423801 1 10.27533302 -9.348790406 0.987090097 0.994519187 1.256132747 0.264827082 0.151573912 0.594068864 1.001859611 0.112909273 0.027185937 4.48E-10 9.348790406 0.26161356 NGS(ph)MGSPVNQQPK ddPTM_HeLa_Curcumin_4h_R1 1 NGSMGSPVNQQPK 13 0 A0A0A0MRW1;A0A0A0MRW0;Q8IW50-3;Q8IW50-2;Q8IW50-4;Q5T586;A0A0A0MRW2;Q5T593;A0A0A0MRW3;Q8IW50-5;Q8IW50-6;Q8IW50;A0A0A0MRV9;Q8IW50-7 A0A0A0MRW1 FAM219A Protein FAM219A 1 0 NGS(0.813)MGS(0.187)PVNQQPK 97.635 0.0096257 3987900 2001.9 2035.3 1837.7 1994 1879.1 2038.4 1134 307.77 2314.5 1804.4 TRUE FALSE FALSE 1843.447503 2211.222263 1905.806779 1985.749356 1856.69296 1615.612862 1165.816988 401.6076562 2060.605141 1867.102766 0.987330498 1.184306672 1.02072945 1.063545828 0.994424621 0.865304734 0.62439894 0.215096707 1.103637774 1 10.86658562 -4.397325038 1.327402651 1.017053409 1.02E-19 0.94479011 0.063748248 0.165913142 0.300877748 0.00918683 0.211349405 4.01E-05 4.397325038 -1.017053409 down S(ph)SSESYTQSFQSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSESYTQSFQSR 13 0 Q9BTU6;E9PAM4 Q9BTU6 PI4K2A Phosphatidylinositol 4-kinase type 2-alpha 1 0 S(0.872)S(0.008)S(0.12)ESYTQSFQSR 293.53 4.15E-73 32021000 1381.2 1287 1406.9 1253.6 1128.7 1539.1 765.46 298.02 1538.3 1492.1 TRUE FALSE FALSE 1271.876563 1398.242545 1459.040952 1248.412935 1115.24099 1219.873311 786.9367475 388.8849261 1369.552339 1543.950364 0.823780733 0.905626617 0.945005089 0.808583595 0.722329562 0.790098788 0.509690445 0.251876573 0.88704428 1 10.59241066 -4.396737388 0.772791032 0.913536045 4.20E-31 0.907038614 0.065291687 0.554997588 0.265589901 0.013355486 0.417892446 4.01E-05 4.396737388 -0.913536045 down LCS(ph)SSSSDTSSR ddPTM_HeLa_Curcumin_4h_R1 1 LCSSSSSDTSSR 12 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 LCS(0.599)S(0.046)S(0.351)S(0.004)SDTSSR 204.32 6.16E-09 236640000 2876.4 2465.4 2223.2 2417.3 2580.5 2309.4 2272 2280.9 2660.8 2240.6 TRUE FALSE FALSE 2648.729905 2678.49819 2305.593748 2407.297853 2549.729223 1830.404408 2335.746205 2976.33591 2368.916897 2318.460683 1.14245194 1.155291616 0.994450225 1.038317307 1.0997509 0.789491243 1.007455603 1.283755179 1.021762808 1 11.17895155 LCSLFYTNEEVAK ddPTM_HeLa_Curcumin_4h_R1 1 LCSLFYTNEEVAK 13 0 A0A0R4J2E8;A8MXP9;P43243;B3KM87;P43243-2;Q68E03 A0A0R4J2E8 MATR3;DKFZp686L22104 Matrin-3 0 0 149.23 3.85E-16 0 225.79 156.62 0 548.96 327.02 204.82 0 156.06 0 0 FALSE FALSE TRUE 207.9184832 170.1575349 0 546.688549 323.1205001 162.3380232 0 203.6419756 0 0 0 LCSSS(ph)SSDTSSR ddPTM_HeLa_Curcumin_4h_R1 1 LCSSSSSDTSSR 12 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 LCS(0.111)S(0.111)S(0.652)S(0.117)S(0.01)DTSSR 178.95 0.00011321 221230000 3326.2 2789.7 2793.3 2497.2 2768.4 3114.1 2206.8 2394.4 2890.6 2522.5 TRUE FALSE FALSE 3062.92776 3030.829237 2896.822155 2486.867248 2735.388638 2468.200557 2268.716869 3124.441538 2573.508412 2610.156687 1.173465093 1.161167547 1.109826919 0.952765503 1.04797871 0.945613943 0.869187999 1.197032175 0.985959358 1 11.3499207 -6.270653759 24.40224344 1.093102788 0.994473091 0.15063089 0.097588208 632.8332412 1675917.101 0.015522167 0.023926346 5.36E-07 6.270653759 -0.098629697 LCSSSS(ph)SDTSSR ddPTM_HeLa_Curcumin_4h_R1 1 LCSSSSSDTSSR 12 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 LCSSS(0.126)S(0.432)S(0.432)DT(0.01)SSR 198.97 9.66E-07 8788300 2541.3 1984.2 1707.9 2045.4 2109.5 2298.8 2189.6 1370.8 2350.5 1948 TRUE FALSE FALSE 2340.153423 2155.705407 1771.196276 2036.936677 2084.34559 1822.002967 2251.034283 1788.75061 2092.656031 2015.692855 1.160967266 1.069461253 0.878703455 1.010539216 1.034059125 0.903909027 1.116754607 0.887412289 1.038181996 1 10.97706011 -6.95922692 24.98885341 1.078075615 0.979481577 0.254221182 0.078542786 165.280835 101296.32 0.013754725 0.018077246 1.10E-07 6.95922692 -0.098594037 LCYVALDFEQEMATAASSSSLEK ddPTM_HeLa_Curcumin_4h_R1 1 LCYVALDFEQEMATAASSSSLEK 23 0 P60709;A0A2R8Y793;Q6S8J3;A0A2R8YEA7;P63261;I3L4N8 P60709;P63261 ACTB;POTEE;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 0 0 116.04 2.55E-11 0 0 0 0 114.55 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 114.0760225 0 0 0 0 0 0 0 LDADS(ph)DS(ph)GDDSDKR ddPTM_HeLa_Curcumin_4h_R1 1 LDADSDSGDDSDKR 14 1 O60333-3 O60333-3 KIF1B Kinesin-like protein KIF1B 2 0 LDADS(0.997)DS(0.943)GDDS(0.059)DKR 94.717 0.01169 6144000 3375.8 2619.4 3475.5 3360.5 3443.6 3426.5 2632.7 1974.9 3055.4 2895.9 TRUE FALSE FALSE 3108.601868 2845.809264 3604.305087 3346.595141 3402.537319 2715.805275 2706.566476 2577.037919 2720.230264 2996.532309 1.03739975 0.949700844 1.202825371 1.116822646 1.135491618 0.906316033 0.90323287 0.860006719 0.907792736 1 11.54907821 -5.128699268 6.83226258 1.041373296 0.887431213 0.434971426 0.083458869 0.174539639 8.9121487 0.010999162 0.028377932 7.44E-06 5.128699268 -0.153942083 LDAFIYDAAVLNY(ph)MAR ddPTM_HeLa_Curcumin_4h_R1 1 LDAFIYDAAVLNYMAR 16 0 O15399 O15399 GRIN2D "Glutamate receptor ionotropic, NMDA 2D" 1 0 LDAFIYDAAVLNY(1)MAR 85.813 0.0063249 0 689.67 682.65 719.74 1011.1 888.02 1071.6 978.79 949.59 874.76 534.55 TRUE FALSE FALSE 635.0818918 741.6552242 746.4141975 1006.916336 877.4309415 849.3380806 1006.252213 1239.11562 778.8010165 553.1255727 1.148169463 1.340844215 1.349447999 1.82041183 1.586314184 1.535524883 1.819211157 2.24020671 1.40800038 1 9.111463234 -1 0.177889566 0.883015694 6.217948238 0.689122152 0.19195648 14.08755817 0.151937627 0.190325155 20.36931624 0.1 1 5.334932545 LDAQSLNLSQEDFDRYMSGQT(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 LDAQSLNLSQEDFDRYMSGQTSPR 24 1 E9PFK9;Q9UJ41;Q9UJ41-4;Q9UJ41-3;A0A0A0MSJ3;Q3HKR1 E9PFK9 RABGEF1 Rab5 GDP/GTP exchange factor 1 0 LDAQSLNLSQEDFDRY(0.16)MS(0.195)GQT(0.513)S(0.132)PR;LDAQSLNLS(0.001)QEDFDRY(0.164)MS(0.188)GQT(0.459)S(0.188)PR ; 73.459 0.00040534 43850000 3466.4 2985.86 3047.6 3223.33 2951.44 4053.8 2964.4 2806.6 3744.8 3426.3 TRUE FALSE FALSE 3192.030782 3243.944434 3160.546737 3209.992715 2916.246006 3212.996184 3047.573086 3662.31942 3334.004809 3545.36367 0.900339452 0.914982139 0.891459109 0.905405767 0.822552008 0.906252922 0.859593929 1.032988365 0.940384434 1 11.79171791 -9.123162971 0.658674835 1.008382787 0.89842121 0.15447711 0.053843053 0.760617495 0.534157593 0.047256849 0.010517481 7.53E-10 9.123162971 -0.109961577 LDAQSLNLSQEDFDRYMSGQTS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 LDAQSLNLSQEDFDRYMSGQTSPR 24 1 E9PFK9;Q9UJ41;Q9UJ41-4;Q9UJ41-3;A0A0A0MSJ3;Q3HKR1 E9PFK9 RABGEF1 Rab5 GDP/GTP exchange factor 1 0 LDAQSLNLSQEDFDRY(0.011)MS(0.228)GQT(0.158)S(0.602)PR 87.28 0.0002644 43347000 1715.8 1546.2 1419.9 1658.9 1238.4 2154 1497.5 1115.7 1678.8 1455.7 TRUE FALSE FALSE 1579.992619 1679.846638 1472.522743 1652.035911 1223.632889 1707.236119 1539.51582 1455.871794 1494.63984 1506.285467 1.048933057 1.115224621 0.977585442 1.096761502 0.812351255 1.13340808 1.022061126 0.96653113 0.992268646 1 10.5567795 FLLS(ph)GAMAGAVSRT(ph)GT(ph)APLDRAK ddPTM_HeLa_Curcumin_4h_R1 1 FLLSGAMAGAVSRTGTAPLDRAK 23 2 Q8N5S1-2;Q8N5S1 Q8N5S1-2 SLC25A41 Solute carrier family 25 member 41 3 0 FLLS(1)GAMAGAVS(0.032)RT(0.984)GT(0.984)APLDRAK 46.027 0.013716 93536000 3000.9 1966.3 2366.1 2757.2 2558.7 3526.9 3221.1 7116.6 3273.6 2869.4 TRUE FALSE FALSE 2763.375598 2136.25821 2453.789747 2745.791437 2528.189174 2795.381184 3311.475397 9286.418579 2914.49427 2969.111436 0.930707943 0.719494117 0.826439088 0.924785578 0.851496897 0.94148746 1.115308559 3.127675999 0.981604878 1 11.53581553 -4.257502276 3.87017798 0.928031179 3.350331685 0.984773728 0.082628685 0.024349694 0.716142149 0.013367717 0.167264554 5.53E-05 4.257502276 2.422300506 up S(ph)RSFDYNYR ddPTM_HeLa_Curcumin_4h_R1 3 SRSFDYNYR 9 1 Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3;O75494-2;O75494 Q5JRI1 SRSF10 Serine/arginine-rich splicing factor 10 1 0 S(0.967)RS(0.033)FDYNYR;S(0.983)RS(0.017)FDYNYR;S(0.647)RS(0.353)FDYNYR ;; 108.57 0.0042019 106812600 4061.03 3279.39 3132.14 3306.19 3967.25 4787.4 4076.85 10472.48 3863.7 3034.43 TRUE FALSE FALSE 3739.59519 3562.845859 3248.219864 3292.509862 3919.943135 3794.439275 4191.235439 13665.49094 3439.861777 3139.876217 1.191000833 1.134709018 1.034505706 1.048611357 1.248438749 1.208467791 1.334840978 4.352238751 1.095540569 1 11.61649197 -4.257466271 4.133176344 1.109390295 4.63342987 0.993741851 0.076540835 0.01555388 0.576666542 0.01392205 0.162946682 5.53E-05 4.257466271 3.524039575 up SGGGGGGGGSS(ph)WGGR ddPTM_HeLa_Curcumin_4h_R1 2 SGGGGGGGGSSWGGR 15 0 Q13151 Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0 1 0 SGGGGGGGGS(0.199)S(0.8)WGGR;SGGGGGGGGS(0.041)S(0.959)WGGR ; 127.07 0.00079115 13904600 4559.2 4540.5 4061.3 4714 4695.6 5754.8 5377.9 12075.9 5284.7 4599.6 TRUE FALSE FALSE 4198.334509 4932.960588 4211.815351 4694.494717 4639.608037 4561.18961 5528.7894 15757.78632 4704.981632 4759.435758 0.882107612 1.036459118 0.884940057 0.986355307 0.974823125 0.958346712 1.161648078 3.310851774 0.988558701 1 12.21657483 -4.257382737 3.814968046 0.953360634 3.557685086 0.995504459 0.047031245 0.013465205 0.376872407 0.007740077 0.09846537 5.53E-05 4.257382737 2.604324451 up LDDQSEDEALELEGPLIT(ph)PGSGK ddPTM_HeLa_Curcumin_4h_R1 1 LDDQSEDEALELEGPLITPGSGK 23 0 G3V5R2 G3V5R2 FERMT2 1 0 LDDQSEDEALELEGPLIT(0.528)PGS(0.472)GK 63.447 0.0044787 26237000 1985.9 1791.1 1593.8 1930.9 1644.1 2068.4 1317.4 1420.9 2423.2 1617.5 TRUE FALSE FALSE 1828.713919 1945.914703 1652.86763 1922.910447 1624.495181 1639.390524 1354.362698 1854.125869 2157.381023 1673.708005 1.09261228 1.16263691 0.987548381 1.148892425 0.97059653 0.979496137 0.809198913 1.107795305 1.288982915 1 10.70883214 -5.55281996 23.93170396 1.056678608 0.954063521 0.199315725 0.113245113 131.8054932 105350.2806 0.012077824 0.024155969 2.80E-06 5.55281996 -0.102615087 LDEDEDEDDADLSK ddPTM_HeLa_Curcumin_4h_R1 1 LDEDEDEDDADLSK 14 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 0 0 231.67 1.22E-19 6070300 1651.1 1641.6 1523.1 1388.1 1712.4 1332.2 1689.2 1367.2 1443.7 1361 FALSE FALSE TRUE 1520.413693 1783.492589 1579.547426 1382.35641 1691.980748 1055.886703 1736.594406 1784.052986 1285.329722 1408.294649 1.079613342 1.266420057 1.121602945 0.98158181 1.20143945 0.749762632 1.233118657 1.266817983 0.912685228 1 10.4597335 -8.443168484 1.144620687 1.012585265 1.106250422 0.121865781 0.15188268 0.927507971 2.471779672 0.044777278 0.028667716 3.60E-09 8.443168484 0.093665157 LDEDEDEDDADLSKYNLDAS(ph)EEEDSNK ddPTM_HeLa_Curcumin_4h_R1 1 LDEDEDEDDADLSKYNLDASEEEDSNK 27 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 LDEDEDEDDADLS(0.001)KY(0.005)NLDAS(0.995)EEEDSNK 91.378 2.68E-06 16336000 2812.3 2710.5 2952.6 2248.2 2854.7 3198.1 2260.7 2518.5 2366.8 2326.3 TRUE FALSE FALSE 2589.703487 2944.783542 3062.025953 2238.897544 2820.659567 2534.77801 2324.129158 3286.379056 2107.167961 2407.138752 1.075843046 1.2233543 1.272060429 0.930107391 1.171789356 1.053025302 0.965515243 1.365263657 0.875382842 1 11.23310359 -7.981486044 1.505047429 1.020224832 1.126857317 0.205676347 0.135186403 0.538102917 2.51354957 0.027917286 0.024365694 1.04E-08 7.981486044 0.106632484 LDEEEEDNEGGEWER ddPTM_HeLa_Curcumin_4h_R1 1 LDEEEEDNEGGEWER 15 0 Q99613-2;Q99613 Q99613-2 EIF3C Eukaryotic translation initiation factor 3 subunit C 0 0 307.77 1.03E-91 32915000 1461.8 1264 1059.7 948.64 1447.1 1246.5 1129 957.9 1095.7 1220.1 FALSE FALSE TRUE 1346.096988 1373.254528 1098.973414 944.714779 1429.844278 987.961849 1160.676701 1249.9593 975.5044513 1262.498384 1.0662168 1.087727751 0.870475106 0.748289892 1.132551372 0.78254504 0.919349059 0.99006804 0.772677782 1 10.30206583 -6.756990945 24.99068221 1.036377143 0.905116852 0.007377588 0.132042523 107.1697613 602061.6349 0.015421286 0.021384915 1.75E-07 6.756990945 -0.131260291 LDEGT(ph)PPEPK ddPTM_HeLa_Curcumin_4h_R1 1 LDEGTPPEPK 10 0 Q9Y4G6;H0YMT1;A0A1B0GVU7;H0YN01 Q9Y4G6 TLN2 Talin-2 1 0 LDEGT(1)PPEPK 132.59 0.0074036 362780000 6439.7 5734.9 5650.1 6306.8 6323.2 6233.7 5767.4 4294.3 6207.7 5331.9 TRUE FALSE FALSE 5929.99095 6230.599202 5859.497676 6280.704133 6247.79997 4940.760352 5929.217722 5603.612301 5526.730841 5517.183128 1.074822208 1.129308029 1.062045167 1.138389643 1.132425701 0.895522269 1.074682059 1.015665453 1.001730541 1 12.42971615 -4.222599883 20.17175403 1.050026812 1.015664397 0.021535535 0.071384227 5812.351545 3017958.724 0.00991054 2.019642535 5.99E-05 4.222599883 -0.034362415 LDEIYVAGLVAHSDLDER ddPTM_HeLa_Curcumin_4h_R1 2 LDEIYVAGLVAHSDLDER 18 0 O60506-4;O60506-3;O60506-2;O60506;F6UXX1 O60506-4 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 0 ; ; 224.64 2.79E-18 10604000 4651.2 4517.2 4902.6 4726 6162.6 6172.3 5299.9 4594.6 4575.4 4189.2 FALSE FALSE TRUE 4283.052612 4907.64664 5084.294669 4706.445064 6089.11502 4892.095404 5448.60093 5995.472389 4073.490067 4334.774388 0.988068173 1.13215734 1.172908718 1.085741643 1.40471325 1.128569786 1.256951445 1.383110596 0.939723663 1 12.08174119 -6.510472549 0.740166208 0.988441538 1.289084846 0.660262575 0.088208303 0.270718584 0.2967974 0.01762478 0.035400557 3.09E-07 6.510472549 0.300643308 LDFIESDS(ph)PCSSEALSKK ddPTM_HeLa_Curcumin_4h_R1 2 LDFIESDSPCSSEALSKK 18 1 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 0 LDFIES(0.024)DS(0.972)PCS(0.004)S(0.001)EALSKK;LDFIES(0.007)DS(0.847)PCS(0.107)S(0.036)EALS(0.003)KK ; 90.882 0.0012223 103277000 5004.7 3928.6 4365.9 4486.8 3933.1 5196.6 3871.8 3214 4914.2 4347.7 TRUE FALSE FALSE 4608.572714 4268.170678 4527.704095 4468.23481 3886.200351 4118.766582 3980.432288 4193.933805 4375.124555 4498.782251 1.024404485 0.948739112 1.006428816 0.993209842 0.863833841 0.915529215 0.884779939 0.932237563 0.972513074 1 12.13531882 -5.835815625 6.621332686 1.005365616 0.899468947 0.715195204 0.027526291 0.067659819 4.827584213 0.003790483 0.006936929 1.46E-06 5.835815625 -0.105896669 LDGLVET(ph)PTGYIESLPR ddPTM_HeLa_Curcumin_4h_R1 4 LDGLVETPTGYIESLPR 17 0 F8VRJ2;F5H4R6;H0YHC3;F8W020;F8W118;F8VXI6;F8VUX1;F8VY35;P55209;F8VV59;B7Z9C2;H0YIV4;F8W0J6;P55209-3;P55209-2 F8VRJ2 NAP1L1 Nucleosome assembly protein 1-like 1 1 0 LDGLVET(0.778)PT(0.053)GYIES(0.169)LPR;LDGLVET(0.992)PT(0.008)GYIESLPR;LDGLVET(0.921)PT(0.076)GY(0.001)IES(0.003)LPR;LDGLVET(0.588)PT(0.059)GYIES(0.353)LPR ;;; 127.66 0.00098281 992293700 9021.9 7862.11 7252.2 7843.8 6107.1 8017.2 7234.3 5381.1 10133.2 10089.4 TRUE FALSE FALSE 8307.807095 8541.675756 7520.972912 7811.344434 6034.276821 6354.342348 7437.274988 7021.772618 9021.613312 10440.0059 0.795766513 0.818167714 0.720399297 0.748212646 0.577995538 0.608653138 0.712382259 0.672583204 0.864138718 1 13.34983491 -8.088238956 0.301131674 1.05778835 0.618167144 0.715397091 0.063142238 0.483162 0.118567807 0.083907383 0.044319103 8.16E-09 8.088238956 -0.439621206 LDGLVETPTGYIES(ph)LPR ddPTM_HeLa_Curcumin_4h_R1 2 LDGLVETPTGYIESLPR 17 0 F8VRJ2;F5H4R6;H0YHC3;F8W020;F8W118;F8VXI6;F8VUX1;F8VY35;P55209;F8VV59;B7Z9C2;H0YIV4;F8W0J6;P55209-3;P55209-2 F8VRJ2 NAP1L1 Nucleosome assembly protein 1-like 1 1 0 LDGLVETPT(0.008)GYIES(0.992)LPR;LDGLVETPTGYIES(1)LPR ; 145.82 0.00027657 19514800 4020.1 3194.1 3537 3387.8 2977.5 5119.7 3691.3 3632.7 3663.8 3866 TRUE FALSE FALSE 3701.904843 3470.183771 3668.084331 3373.782181 2941.995257 4057.816509 3794.867943 4740.293507 3261.890306 4000.343212 0.925396809 0.867471511 0.916942406 0.843373181 0.735435712 1.014367091 0.94863559 1.184971703 0.815402613 1 11.96590807 -4.067510028 2.001137053 0.931303113 1.372481164 0.458344581 0.087000147 1.153128976 3.08472893 0.012548402 1.109652819 8.56E-05 4.067510028 0.441178051 LDGLVETPTGYIESLPR ddPTM_HeLa_Curcumin_4h_R1 1 LDGLVETPTGYIESLPR 17 0 F8VRJ2;F5H4R6;H0YHC3;F8W020;F8W118;F8VXI6;F8VUX1;F8VY35;P55209;F8VV59;B7Z9C2;H0YIV4;F8W0J6;P55209-3;P55209-2 F8VRJ2 NAP1L1 Nucleosome assembly protein 1-like 1 0 0 141.37 0.0028389 6702300 371.93 203.31 513.89 247.42 468.82 514.2 427.18 393.36 312.81 405.06 FALSE FALSE TRUE 342.491348 220.8832105 532.9352155 246.3962416 463.2296277 407.5491238 439.1655211 513.2936532 278.4955256 419.1358048 0.817136938 0.526996758 1.271509638 0.587867318 1.105201756 0.972355783 1.04778813 1.22464759 0.664451766 1 8.711273959 -4.160523902 0.832774445 0.892919869 1.44578927 0.223916275 0.21878186 3.261946317 1.4699567 0.031011511 1.719697006 6.91E-05 4.160523902 0.552869402 LDGT(ph)S(ph)LT(ph)RT(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 LDGTSLTRTGK 11 1 F8W703 F8W703 ROBO2 4 0 LDGT(1)S(1)LT(1)RT(1)GK 53.967 0.016724 2100100 1121.1 1616.2 1206.3 970.94 799.91 938.09 1231.5 855.28 1253 1672.4 TRUE FALSE FALSE 1032.363752 1755.897126 1251.006539 966.9225075 790.3715957 743.5195595 1266.052576 1116.050935 1115.549035 1730.515776 0.596564196 1.014666928 0.722909642 0.558748161 0.456726028 0.429651997 0.73160418 0.644923872 0.644633843 1 10.75698638 -6.401857468 4.007998535 0.82125799 0.56088849 0.389809772 0.147298717 0.21681984 6.016020731 0.02781801 0.043063538 3.96E-07 6.401857468 -0.2603695 LDHGEES(ph)NES(ph)AESSSNWEK ddPTM_HeLa_Curcumin_4h_R1 2 LDHGEESNESAESSSNWEK 19 0 Q9H4L7-2;Q9H4L7 Q9H4L7-2 SMARCAD1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 2 0 LDHGEES(1)NES(0.998)AES(0.002)SSNWEK;LDHGEES(1)NES(0.999)AESSS(0.001)NWEK ; 113.08 0.00081467 31688000 4373.3 3804.3 3269 4211.5 4537.6 4420.4 3849 2942.6 3862.1 3434.7 TRUE FALSE FALSE 4027.14869 4133.12674 3390.152016 4194.073929 4483.492084 3503.559212 3956.992581 3839.785194 3438.437292 3554.055569 1.133113597 1.162932503 0.95388267 1.180081135 1.261514345 0.985791905 1.113373864 1.080395373 0.967468636 1 11.79525052 -9.322780926 0.955753973 0.997393667 1.110410107 0.246542114 0.085697721 0.786384005 1.239883306 0.06307983 0.015265729 4.76E-10 9.322780926 0.11301644 LDHLAEK ddPTM_HeLa_Curcumin_4h_R1 4 LDHLAEK 7 0 O43707;O43707-2;P12814-4;P12814-3;P12814;P12814-2;H9KV75 O43707;P12814-4 ACTN4;ACTN1 Alpha-actinin-4;Alpha-actinin-1 0 0 ;;; ;;; 109.86 0.010289 142444100 60450 47445 59580 39797.3 57266 75440 57783 58226 37171.8 45433.4 FALSE FALSE TRUE 55665.31871 51545.93439 61788.08721 39632.62932 56583.14035 59792.89362 59404.23547 75978.83936 33094.14654 47012.20727 1.184060948 1.096437232 1.314298792 0.843028473 1.203583997 1.271858887 1.263591712 1.616151289 0.703947942 1 15.5207478 -1.000000277 0.634883005 1.090855838 42.64594211 0.498719909 0.172649871 93.37039851 0.590053114 0.021257992 5446.620645 0.099999936 1.000000277 41.55508627 LDIDS(ph)PPITAR ddPTM_HeLa_Curcumin_4h_R1 4 LDIDSPPITAR 11 0 P14618;B4DNK4;H3BU13;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BN34;H3BQZ3 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 1 0 LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(1)PPITAR;LDIDS(0.996)PPIT(0.004)AR ;;; 190.34 4.02E-05 895700000 22352.9 19102.4 20149.3 20223.5 20310.4 25227.9 19121.9 18584.4 21232.1 19226.6 TRUE FALSE FALSE 20583.64438 20753.52634 20896.05078 20139.82052 20068.21175 19995.34916 19658.40905 24250.69801 18902.99175 19894.72292 1.034628352 1.043167398 1.05033133 1.012319729 1.008720344 1.005057936 0.988121781 1.218951282 0.950151044 1 14.28009819 -4.256282036 24.99980383 1.01776771 1.218951366 0.828117086 0.028336332 127.710909 619048.5059 0.002973071 0.033441909 5.54E-05 4.256282036 0.201183656 LDIDSPPIT(ph)AR ddPTM_HeLa_Curcumin_4h_R1 1 LDIDSPPITAR 11 0 P14618;B4DNK4;H3BU13;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BN34;H3BQZ3 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 1 0 LDIDSPPIT(1)AR 196.7 4.58E-05 7447200 2873 2392.7 2699.7 2924.6 2679.9 3036.8 2676 2564.2 2859.6 2623.8 TRUE FALSE FALSE 2645.599018 2599.514326 2799.753257 2912.49878 2647.943943 2406.933448 2751.081358 3346.012776 2545.909034 2714.976855 0.974446251 0.957472003 1.03122546 1.072752711 0.975309951 0.886539215 1.013298273 1.232427735 0.937727712 1 11.40672418 -4.272692581 4.610993227 0.987238095 1.245609366 0.707396706 0.048270244 0.071075438 3.9485016 0.0063619 0.058020129 5.34E-05 4.272692581 0.25837127 LDIDSPPITAR ddPTM_HeLa_Curcumin_4h_R1 4 LDIDSPPITAR 11 0 P14618;B4DNK4;H3BU13;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25;H3BN34;H3BQZ3 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ;;; ;;; 182.16 6.38E-08 152542000 9194 7841.3 7654.8 7511.1 7400.4 10753.6 8025.5 7327.5 8511.4 7811.2 FALSE FALSE TRUE 8466.285199 8519.067032 7938.493622 7480.021058 7312.155063 8523.182142 8250.67393 9561.621018 7577.720714 8082.638619 1.047465512 1.053995785 0.982166097 0.925442966 0.904674254 1.054504914 1.02078966 1.182982621 0.937530561 1 12.98061063 -4.11349465 2.188694781 1.008634011 1.282611764 0.508454839 0.054180421 0.803268419 2.9967944 0.007722093 0.492531236 7.70E-05 4.11349465 0.273977752 LDIPTGTT(ph)PQRK ddPTM_HeLa_Curcumin_4h_R1 1 LDIPTGTTPQRK 12 1 P52732 P52732 KIF11 Kinesin-like protein KIF11 1 0 LDIPT(0.085)GT(0.239)T(0.676)PQRK 129.54 0.00045765 0 3995.7 3762.5 3660.9 3928.9 4039.8 4971.5 4081.4 2571.1 4047.7 3308 TRUE FALSE FALSE 3679.436129 4087.713735 3796.576174 3912.643253 3991.628023 3940.35486 4195.913099 3355.016554 3603.677437 3422.952754 1.074930446 1.194206882 1.109152374 1.143060841 1.166135881 1.15115666 1.225816832 0.98015275 1.05279789 1 11.74102566 -7.90410206 0.942717634 1.014579298 1.143258094 0.302192877 0.06465445 0.310837483 0.589291391 0.016334616 0.0135187 1.25E-08 7.90410206 0.128678796 LDLAGRDLTDYLMK ddPTM_HeLa_Curcumin_4h_R1 2 LDLAGRDLTDYLMK 14 1 P60709;A0A2R8Y793;P63267-2;A0A2R8YEA7;Q562R1;P63261;I3L3I0;I3L1U9;I3L4N8;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;ACTG2;ACTBL2;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;Beta-actin-like protein 2;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 0 0 ; ; 156.52 0.00032016 33504000 7484.5 4691.5 4532.5 6495.4 3712 8130.6 5260.1 4898.1 9495.3 7885.7 FALSE FALSE TRUE 6892.093927 5097.012355 4700.478437 6468.523756 3667.736824 6444.221909 5407.684249 6391.508142 8453.689346 8159.727488 0.844647562 0.624654728 0.576058262 0.792737719 0.449492563 0.789759452 0.662728536 0.783299216 1.036025941 1 12.99430526 -7.673054552 1.329965861 0.955035101 0.665626631 0.601942725 0.109518403 0.187138009 0.682571879 0.02251435 0.022281586 2.12E-08 7.673054552 -0.28940847 IISIFSGTEK(ac)GSK ddPTM_HeLa_Curcumin_4h_R1 2 IISIFSGTEKGSK 13 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 0 1 ; IISIFSGTEK(1)GSK;IISIFSGTEK(1)GSK 241.92 3.72E-49 2737980 1089.11 742.98 879.81 842.05 958.95 1555.06 1578.91 1967.43 809.36 793.39 FALSE TRUE FALSE 1002.905794 807.1998805 912.4165326 838.5658202 947.5151476 1232.523027 1623.209965 2567.29035 720.5752329 820.9602434 1.221625289 0.983238698 1.111401605 1.021445103 1.154154729 1.501318775 1.97720898 3.127179873 0.877722446 1 9.681168548 -4.104302035 1.063654965 1.088442536 4.695313726 0.976384057 0.100205384 0.227319872 0.163020284 0.014645797 0.99743915 7.86E-05 4.104302035 3.60687119 up LDLLGNLPGS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 LDLLGNLPGSK 11 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 LDLLGNLPGS(1)K 141.85 0.0012433 18461000 2593.3 1908.8 2328.5 3154.1 2885.5 5614.9 5883.7 1092.7 3107.4 1801.4 TRUE FALSE FALSE 2388.037569 2073.788167 2414.796258 3141.04917 2851.092297 4450.306447 6048.780787 1425.8592 2766.525994 1863.998516 1.281137055 1.112548185 1.295492586 1.685113557 1.529557171 2.38750536 3.245056654 0.764946532 1.484188947 1 10.864185 -5.829406699 1.337452855 1.138829533 2.199017504 0.261155364 0.597794521 0.321980044 1.150932366 0.087036951 0.21586543 1.48E-06 5.829406699 1.060187971 LDLLGNLPGS(ph)KR ddPTM_HeLa_Curcumin_4h_R1 2 LDLLGNLPGSKR 12 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 LDLLGNLPGS(1)KR;LDLLGNLPGS(1)KR ; 137.81 0.0023089 31401000 3284.1 2317.2 2378.3 3602.4 3472.5 5748.9 6633.7 1714.71 3838.7 2196.52 TRUE FALSE FALSE 3024.16002 2517.488443 2466.44189 3587.494223 3431.092705 4556.513337 6819.823768 2237.517185 3417.604214 2272.848907 1.330559199 1.107635635 1.085176354 1.578412983 1.509599998 2.004758576 3.000561871 0.984454875 1.50366538 1 11.15028607 -5.651565946 1.550172263 1.15566292 2.082190909 0.303474473 0.485360935 0.270146984 1.297262385 0.067457652 0.17685164 2.23E-06 5.651565946 0.926527988 LDLTENLT(ph)GSK ddPTM_HeLa_Curcumin_4h_R1 1 LDLTENLTGSK 11 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 LDLTENLT(0.621)GS(0.379)K 124.81 0.010357 7454900 1837.6 1703.1 1843.8 2632.5 2012.8 4626 4770.5 1265 2665.2 1853.7 TRUE FALSE FALSE 1692.152021 1850.308375 1912.13285 2621.607413 1988.798675 3666.515454 4904.347391 1650.692677 2372.834228 1918.115937 0.88219486 0.964648872 0.996880748 1.366761707 1.036850086 1.911519207 2.556856599 0.860580242 1.237065071 1 10.90547421 -5.277367255 7.393049485 0.986002839 1.855359275 0.365482073 0.413126905 0.096003802 30.52992864 0.052541071 0.122100438 5.28E-06 5.277367255 0.869356435 LDLTENLTGS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 LDLTENLTGSK 11 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 LDLTENLT(0.004)GS(0.996)K 113.25 0.0055144 21501000 487.91 328.88 552.12 643.87 613.14 996.6 1223 274.82 626.6 371.13 TRUE FALSE FALSE 449.2914087 357.3069217 572.5820529 641.2058365 605.828706 789.893926 1257.314088 358.6113529 557.8635477 384.0267399 1.169948241 0.930421985 1.49099527 1.669690597 1.577569068 2.056872202 3.274027452 0.933818705 1.452668499 1 8.585062959 -5.973504535 1.013364613 1.068776135 2.17067308 0.296128694 0.560756964 0.363188527 0.730960323 0.085982404 0.223226958 1.06E-06 5.973504535 1.101896945 LDLTENLTGS(ph)KR ddPTM_HeLa_Curcumin_4h_R1 2 LDLTENLTGSKR 12 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 LDLTENLT(0.006)GS(0.994)KR;LDLTENLT(0.006)GS(0.994)KR ; 146.59 0.0012257 39823000 2669.1 1979.65 2832.6 3261.6 2871.7 6444.8 5834.3 1222.38 3638.5 2039.4 TRUE FALSE FALSE 2457.837919 2150.762125 2937.578648 3248.104363 2837.456853 5108.075832 5997.994756 1595.078035 3239.365653 2110.268998 1.164703609 1.019188609 1.392039901 1.539189727 1.344594862 2.420580427 2.842289187 0.755864791 1.535048686 1 11.0432112 -5.861175271 1.249143527 1.084171706 2.037502111 0.225355134 0.54505426 0.342784285 1.063472565 0.07981683 0.200402525 1.38E-06 5.861175271 0.953330406 LDNT(ph)PAS(ph)PPRSPAEPNDIPIAK ddPTM_HeLa_Curcumin_4h_R1 1 LDNTPASPPRSPAEPNDIPIAK 22 1 H0Y911;Q4VXL4;D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-2;O95359-6;O95359-1;O95359-5;O95359-3;O95359;E9PGB3;H0Y8P9 H0Y911 TACC2 Transforming acidic coiled-coil-containing protein 2 2 0 LDNT(0.917)PAS(0.923)PPRS(0.16)PAEPNDIPIAK 58.477 0.017927 8029400 1916.3 1543.9 1749.3 2184.3 2146.4 2286.4 2084.1 2043.6 2011.8 1630.4 TRUE FALSE FALSE 1764.622833 1677.347837 1814.130597 2175.261945 2120.805582 1812.174867 2142.574237 2666.684232 1791.110573 1687.056279 1.045977455 0.994245336 1.075323106 1.289383154 1.257104229 1.07416385 1.270007565 1.580672955 1.061678022 1 10.72029239 -1 0.336006274 1.011126415 6.352080992 0.720568143 0.092360962 20.06880725 0.253896149 0.0291664 67.88785505 0.1 1 5.340954577 LDNVPHT(ph)PSSYIETLPK ddPTM_HeLa_Curcumin_4h_R1 2 LDNVPHTPSSYIETLPK 17 0 C9J6D1;Q99733;Q99733-2;E9PNJ7;A8MXH2;E9PS34;E9PNW0;E9PJJ2;E9PKI2;E9PP22 C9J6D1 NAP1L4 Nucleosome assembly protein 1-like 4 1 0 LDNVPHT(0.521)PS(0.368)S(0.11)Y(0.001)IETLPK;LDNVPHT(0.802)PS(0.083)S(0.083)Y(0.001)IET(0.031)LPK ; 126.43 0.0010884 162546000 6832.7 6152.7 5613.7 5478.9 6803.9 14789 11812.4 5064.4 8362.3 6521.9 TRUE FALSE FALSE 6291.884585 6684.511972 5821.74866 5456.229764 6722.767936 11721.59469 12143.82415 6608.512246 7444.976611 6748.53554 0.932333326 0.990512969 0.862668445 0.808505746 0.996181749 1.736909382 1.799475469 0.979251307 1.103198845 1 12.72035875 -5.315573489 7.810559357 0.949719507 1.533997418 0.569360771 0.21836953 0.134668624 17.79775039 0.028222148 0.063526237 4.84E-06 5.315573489 0.584277911 LDNVPHTPS(ph)SYIETLPK ddPTM_HeLa_Curcumin_4h_R1 1 LDNVPHTPSSYIETLPK 17 0 C9J6D1;Q99733;Q99733-2;E9PNJ7;A8MXH2;E9PS34;E9PNW0;E9PJJ2;E9PKI2;E9PP22 C9J6D1 NAP1L4 Nucleosome assembly protein 1-like 4 1 0 LDNVPHT(0.015)PS(0.484)S(0.414)YIET(0.086)LPK 162.59 0.00013106 14220000 2796.7 2487.2 2691.1 3119.7 2571.7 3539.7 2807.4 2871.2 2815.1 3113.4 TRUE FALSE FALSE 2575.338244 2702.182485 2790.834533 3106.791508 2541.034157 2805.526319 2886.168088 3746.615663 2506.290573 3221.590418 0.799399647 0.838772822 0.866290922 0.964365765 0.788751463 0.870851336 0.895883 1.162970824 0.777966857 1 11.65355737 -4.261691973 6.417091025 0.889684437 1.168685116 0.587853865 0.072153149 0.079871256 19.03947242 0.011561538 0.096522937 5.47E-05 4.261691973 0.279000678 LDPAALS(ph)PANPR ddPTM_HeLa_Curcumin_4h_R1 2 LDPAALSPANPR 12 0 Q9BZ71;Q9BZ71-3;Q9BZ71-2 Q9BZ71 PITPNM3 Membrane-associated phosphatidylinositol transfer protein 3 1 0 LDPAALS(1)PANPR;LDPAALS(1)PANPR ; 141.65 0.0011033 9702400 3277.5 2545 2957.9 2897.6 2921.5 3868.5 3182.6 2027.37 3721.6 2767.1 TRUE FALSE FALSE 3018.082417 2764.97846 3067.522376 2885.610499 2886.663021 3066.129493 3271.89519 2645.50578 3313.349791 2863.256519 1.054073359 0.965676125 1.071340397 1.007807187 1.008174783 1.070853929 1.142718149 0.923949972 1.157196279 1 11.48344121 -5.262351609 24.98544207 1.022637301 1.05552843 0 0.071275708 175.3305012 4802261.718 0.007539994 0.017940772 5.47E-06 5.262351609 0.032891129 LDPGSEETQTLVR ddPTM_HeLa_Curcumin_4h_R1 1 LDPGSEETQTLVR 13 0 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 0 130.01 0.0013862 2711500 402.17 292.13 445.57 489.28 423.72 308.9 248.44 366.98 285.84 348.25 FALSE FALSE TRUE 370.3378201 317.3804155 462.0832162 487.255489 418.6674157 244.830658 255.4105578 478.8705126 254.4840671 360.3516616 1.027712259 0.880751914 1.282311879 1.352166622 1.161830124 0.679421477 0.708781407 1.328897751 0.706210334 1 8.493261687 -3.950392061 11.0247711 1.017543953 2.426119953 0.15466652 0.229914397 42696.119 381592.7257 0.02944427 1141339.222 0.000112101 3.950392061 1.408576001 LDPPPS(ph)PHANR ddPTM_HeLa_Curcumin_4h_R1 2 LDPPPSPHANR 11 0 E7EUN2;H7C211;H7C0A7;A0A087X1U1;F5GXM9;Q9UPQ3-2;Q9UPQ3 E7EUN2 AGAP1 "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1" 1 0 LDPPPS(1)PHANR;LDPPPS(1)PHANR ; 86.944 0.0097653 62836000 8377.3 6964.5 7013.2 7808 8229.7 8541.2 6697.6 5715.7 7633.1 7224.5 TRUE FALSE FALSE 7714.227865 7566.480347 7273.115361 7775.692565 8131.566202 6769.658841 6885.51663 7458.390618 6795.768027 7475.550837 1.031927684 1.012163587 0.972920327 1.040149781 1.087754786 0.905573246 0.921071474 0.997704488 0.909065857 1 12.86796417 -5.244336511 24.99832643 1.018055722 0.93941191 0.255142892 0.049693778 527.1987057 770576.1599 0.005017069 0.012757188 5.70E-06 5.244336511 -0.078643812 LDPPPS(ph)PHSNR ddPTM_HeLa_Curcumin_4h_R1 1 LDPPPSPHSNR 11 0 Q96P47;Q96P47-2;Q96P47-4;H0Y873 Q96P47 AGAP3 "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3" 1 0 LDPPPS(0.973)PHS(0.027)NR 86.539 0.009966 26130000 6934.6 6082.8 5573.9 6140.6 6370.5 6885.8 4792.8 3471.5 6956.1 5319.2 TRUE FALSE FALSE 6385.719093 6608.570128 5780.473637 6115.191824 6294.535948 5457.607461 4927.273069 4529.944369 6193.033233 5504.041804 1.160187244 1.20067586 1.050223425 1.111036588 1.143620665 0.991563592 0.895209965 0.823021432 1.125179178 1 12.42627571 -4.832698246 2.214628713 1.091456467 0.836926871 0.75521946 0.057353096 0.160632189 1.513007765 0.010709643 0.050915917 1.47E-05 4.832698246 -0.254529596 LDPS(ph)PPSPQPK ddPTM_HeLa_Curcumin_4h_R1 1 LDPSPPSPQPK 11 0 A0A3B3IU55 A0A3B3IU55 1 0 LDPS(0.576)PPS(0.424)PQPK 90.793 0.016709 12782000 4428.1 3496 4042.5 3681.3 4326.1 4614.5 3332.8 2811.2 4021.4 3560 TRUE FALSE FALSE 4077.611212 3798.178662 4192.318606 3666.067756 4274.514083 3657.400684 3426.309398 3668.321939 3580.262481 3683.709735 1.10693065 1.031074361 1.138069747 0.995210812 1.160382981 0.992858001 0.930124696 0.995822745 0.971917642 1 11.84694367 -5.013971789 24.57508927 1.059565952 0.962603105 0.297637885 0.060755583 418.7843134 736607.9352 0.008014903 0.021427831 9.68E-06 5.013971789 -0.096962847 LDQPVS(ph)APPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 LDQPVSAPPSPR 12 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 2 0 LDQPVS(1)APPS(1)PR 105.63 0.016419 362810000 6076.9 4830.3 4954.8 5666.6 5055.2 6298.8 5524.9 6740.4 5720.2 5330.9 TRUE FALSE FALSE 5595.906953 5247.809609 5138.429247 5643.153111 4994.920042 4992.357878 5679.913824 8795.516931 5092.708371 5516.148378 1.014459106 0.951353961 0.931524842 1.023024169 0.905508645 0.90504416 1.029688369 1.594503325 0.923236291 1 12.42944555 -4.264119976 4.621660756 0.985496148 1.630943175 0.93824656 0.048327198 0.031996748 1.811872967 0.006733953 0.066454336 5.44E-05 4.264119976 0.645447027 LDQPVSAPPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 LDQPVSAPPSPR 12 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 0 LDQPVSAPPS(1)PR;LDQPVSAPPS(1)PR;LDQPVSAPPS(1)PR;LDQPVSAPPS(1)PR ;;; 163.9 0.0001207 586243000 12346.6 9605.4 9234.5 9556.2 9627.6 11957.2 8933.1 15802.6 11595.2 8284 TRUE FALSE FALSE 11369.35358 10435.64798 9576.738693 9516.658976 9512.797158 9477.141935 9183.738744 20620.73999 10323.23557 8571.868383 1.326356527 1.217429796 1.117228854 1.110219914 1.109769391 1.105609829 1.071381213 2.405629563 1.204315688 1 13.06539398 -4.259393553 24.99900082 1.145493196 2.405629993 0.951829092 0.085391662 38.85449184 474748.0489 0.017019684 0.14947573 5.50E-05 4.259393553 1.260136798 LDRETEELHHDR ddPTM_HeLa_Curcumin_4h_R1 4 LDRETEELHHDR 12 1 O60869-2;O60869-3;O60869 O60869-2 EDF1 Endothelial differentiation-related factor 1 0 0 ;;; ;;; 107.97 0.0028559 157873000 19658.9 15966.1 16299.7 17560.7 17587.5 22044.9 15838.4 15064.2 21447.9 17299.5 FALSE FALSE TRUE 18102.87732 17346.13854 16903.78122 17488.03848 17377.78055 17472.53924 16282.78288 19657.20523 19095.11903 17900.65634 1.011296847 0.969022488 0.944310695 0.976949568 0.970790133 0.976083721 0.909619322 1.098127625 1.066727313 1 14.12772487 -7.259852168 24.58465663 1.005334622 0.973556311 0.124484746 0.049336027 185.7338205 2876875.661 0.006845918 0.008149601 5.50E-08 7.259852168 -0.031778312 LDRPAGGPSAESPRPSSAY(ph)NGDLNGLLVPDPLCSGDSTSANK ddPTM_HeLa_Curcumin_4h_R1 1 LDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLCSGDSTSANK 42 2 Q6P2E9 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 0 LDRPAGGPS(0.092)AES(0.187)PRPS(0.187)S(0.187)AY(0.347)NGDLNGLLVPDPLCSGDSTSANK 40.87 0.0060156 31160000 808.08 954.35 746.23 802.74 749.91 873.79 767.26 305.57 857.4 622.42 TRUE FALSE FALSE 744.1196153 1036.839761 773.8859403 799.4184746 740.967813 692.5561044 788.7872506 398.7368863 763.3453651 644.0490487 1.155377245 1.609877017 1.201594726 1.241238499 1.150483515 1.075315779 1.224731645 0.619109503 1.18522862 1 9.331026753 -4.255850379 24.41456669 1.143083727 0.619109188 0.509068579 0.162686142 328.7120253 1435858.695 0.025065571 0.289908254 5.55E-05 4.255850379 -0.523974539 RTADSSSS(ph)EDEEEYVVEK ddPTM_HeLa_Curcumin_4h_R1 1 RTADSSSSEDEEEYVVEK 18 1 P45973;F8VNY3 P45973 CBX5 Chromobox protein homolog 5 1 0 RT(0.261)ADS(0.025)S(0.038)S(0.18)S(0.496)EDEEEYVVEK 93.388 0.0010792 18023000 5795.5 4220.3 4300.7 5179.7 5590.6 6423.3 3441.6 1007.7 5733.7 5193.7 TRUE FALSE FALSE 5336.78006 4585.083927 4460.087725 5158.267774 5523.935746 5091.035174 3538.162033 1314.943091 5104.727455 5374.180688 0.993040683 0.853168919 0.829910266 0.959824031 1.027865654 0.947313734 0.658363058 0.244677871 0.949861523 1 12.39182911 -4.39468543 1.922411559 0.973276331 0.128911676 0.918778695 0.064330572 0.121259322 0.573138204 0.010387329 0.164275102 4.03E-05 4.39468543 -0.844364655 down LDS(ph)PPPS(ph)PITEASEAAEAAEAGNLAVSSR ddPTM_HeLa_Curcumin_4h_R1 10 LDSPPPSPITEASEAAEAAEAGNLAVSSR 29 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 2 0 LDS(0.998)PPPS(0.998)PIT(0.004)EASEAAEAAEAGNLAVSSR;LDS(0.892)PPPS(0.974)PIT(0.129)EAS(0.006)EAAEAAEAGNLAVSSR;LDS(0.945)PPPS(0.967)PIT(0.078)EAS(0.01)EAAEAAEAGNLAVSSR;LDS(1)PPPS(1)PITEASEAAEAAEAGNLAVSSR;LDS(0.992)PPPS(0.955)PIT(0.052)EAS(0.001)EAAEAAEAGNLAVSSR;LDS(0.988)PPPS(0.992)PIT(0.015)EAS(0.005)EAAEAAEAGNLAVSSR;LDS(1)PPPS(0.996)PIT(0.004)EASEAAEAAEAGNLAVSSR;LDS(1)PPPS(0.998)PIT(0.003)EASEAAEAAEAGNLAVSSR;LDS(0.997)PPPS(0.977)PIT(0.025)EAS(0.001)EAAEAAEAGNLAVSSR;LDS(0.998)PPPS(0.976)PIT(0.026)EASEAAEAAEAGNLAVSSR ;;;;;;;;; 119.74 4.12E-12 40511200 5180.93 3394.283 4458.81 4321.9 4714.1 6231.74 5251.31 6056.94 5173.61 4405.27 TRUE FALSE FALSE 4770.853924 3687.669698 4624.057421 4304.017123 4657.887436 4939.206878 5398.647625 7903.673123 4606.077927 4558.352805 1.046617962 0.808991725 1.014414114 0.944204476 1.021835658 1.083550811 1.184341769 1.733887977 1.010469818 1 12.15429687 -3.899477585 1.311286216 0.999932927 2.737908866 0.917965955 0.067179949 0.619979672 0.486872598 0.010147312 1.808895507 0.000126044 3.899477585 1.737975939 LDS(ph)PPPSPITEASEAAEAAEAGNLAVSSR ddPTM_HeLa_Curcumin_4h_R1 4 LDSPPPSPITEASEAAEAAEAGNLAVSSR 29 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 LDS(0.996)PPPS(0.004)PITEASEAAEAAEAGNLAVSSR;LDS(0.906)PPPS(0.087)PIT(0.007)EASEAAEAAEAGNLAVSSR;LDS(0.971)PPPS(0.029)PITEASEAAEAAEAGNLAVSSR;LDS(0.7)PPPS(0.262)PIT(0.034)EAS(0.005)EAAEAAEAGNLAVSSR ;;; 243.87 4.85E-52 55132700 2472.34 1729.37 2005.35 2286.77 2338.13 2458.54 1735.37 1224.61 2443.51 1967.92 TRUE FALSE FALSE 2276.65168 1878.849037 2079.670035 2277.307952 2310.249327 1948.611091 1784.059812 1597.987952 2175.463066 2036.305074 1.118030746 0.922675615 1.021295906 1.118353031 1.134530065 0.956934752 0.876125996 0.784748794 1.06833848 1 10.991738 -4.786556434 2.252303835 1.053181401 0.80305675 0.674302601 0.062691782 0.155614366 1.505596187 0.010026508 0.050443325 1.63E-05 4.786556434 -0.250124651 TLS(ph)SSAQEDIIR ddPTM_HeLa_Curcumin_4h_R1 3 TLSSSAQEDIIR 12 0 Q9H788-2;Q9H788 Q9H788-2 SH2D4A SH2 domain-containing protein 4A 1 0 T(0.019)LS(0.473)S(0.473)S(0.036)AQEDIIR;TLS(0.48)S(0.48)S(0.04)AQEDIIR;TLS(0.989)S(0.011)S(0.001)AQEDIIR ;; 239.38 2.80E-26 401476100 3553.45 2407.46 2813.94 3490.78 3038.94 4142.65 4256.24 14768.8 3319.17 2752.14 TRUE FALSE FALSE 3272.190683 2615.550115 2918.227092 3476.336077 3002.702625 3283.417693 4375.658639 19271.73913 2955.065355 2847.77666 1.149033465 0.918453386 1.024738749 1.220719351 1.054402428 1.152975842 1.536517488 6.767293026 1.037674547 1 11.47562029 -4.257323112 3.931596437 1.076854961 7.323828731 0.997590764 0.083510644 0.009734748 0.302296208 0.014149175 0.174417573 5.53E-05 4.257323112 6.24697377 up LDS(ph)SPVSSPR ddPTM_HeLa_Curcumin_4h_R1 2 LDSSPVSSPR 10 0 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 0 LDS(0.835)S(0.164)PVS(0.001)SPR;LDS(0.857)S(0.143)PVSSPR ; 160.72 0.00061062 193668000 18511.4 14502.9 17127.1 18465.7 17508.2 19659.2 15241 14218.4 20663.1 18147.6 TRUE FALSE FALSE 17046.20316 15756.46605 17761.84539 18389.29383 17299.42615 15581.66032 15668.62144 18553.52471 18396.40963 18778.22775 0.907764214 0.839081636 0.945874426 0.979288039 0.921249139 0.829772677 0.834403632 0.988033853 0.979666978 1 14.19677329 -9.056097134 0.685154328 1.005849547 0.902339636 0.267498287 0.054719649 0.831200452 0.66218799 0.048727966 0.012193729 8.79E-10 9.056097134 -0.103509912 LDS(ph)VPVEEQEEFK ddPTM_HeLa_Curcumin_4h_R1 1 LDSVPVEEQEEFK 13 0 E9PQC4;Q9BZD4;B1AQT4;E9PP32 E9PQC4 NUF2 Kinetochore protein Nuf2 1 0 LDS(1)VPVEEQEEFK 88.507 0.013891 2223100 334.48 217.86 237.98 342.13 310.1 347.06 365.71 4243.4 231.43 167.54 TRUE FALSE FALSE 308.0055551 236.6908476 246.7997481 340.7143567 306.40226 275.0758438 375.9708383 5537.193126 206.042708 173.3620025 1.776661267 1.365298302 1.423609237 1.965334685 1.767413018 1.586713581 2.168703827 31.9400621 1.188511352 1 7.437643913 -4.261300343 6.216955718 1.473835018 32.6636681 0.999093478 0.274393043 0.003286662 0.669881398 0.050600631 0.429972974 5.48E-05 4.261300343 31.18983308 LDSDAGFHS(ph)LPR ddPTM_HeLa_Curcumin_4h_R1 1 LDSDAGFHSLPR 12 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 0 LDS(0.42)DAGFHS(0.58)LPR 85.28 0.0092786 5687800 5548.2 4129.6 4364.1 4263.9 5322.2 6684.4 4695.6 1691.9 5438.2 4374.5 TRUE FALSE FALSE 5109.054116 4486.544223 4525.837385 4246.257112 5258.736241 5297.980091 4827.345898 2207.752521 4841.643066 4526.513549 1.1286952 0.991169953 0.999850621 0.938085585 1.161763062 1.170432836 1.066460057 0.487737968 1.069618596 1 12.14418456 -4.261004613 24.8344284 1.059351705 0.487737789 0.84393408 0.07362662 10.03585164 573051.8174 0.011281041 0.088975884 5.48E-05 4.261004613 -0.571613916 LDSQPQETS(ph)PELPR ddPTM_HeLa_Curcumin_4h_R1 3 LDSQPQETSPELPR 14 0 O14545 O14545 TRAFD1 TRAF-type zinc finger domain-containing protein 1 1 0 LDSQPQET(0.203)S(0.797)PELPR;LDSQPQET(0.23)S(0.77)PELPR;LDSQPQET(0.229)S(0.771)PELPR ;; 167.92 0.00020917 809574000 12855.4 11134.9 11083.6 12263.1 11033.2 12997 8580.1 6784.6 13672.2 11128.9 TRUE FALSE FALSE 11837.88153 12097.35114 11494.36797 12212.35854 10901.6363 10301.27569 8820.834514 8853.193308 12172.39387 11515.62845 1.027983977 1.050515931 0.998153772 1.060503002 0.946681837 0.894547418 0.765988114 0.768798103 1.05703253 1 13.49130553 -5.054228469 1.554213465 1.018043151 0.75373279 0.930781546 0.028085607 0.068326881 0.299466407 0.003695712 0.017222235 8.83E-06 5.054228469 -0.264310362 LDSS(ph)PSVSSTLAAK ddPTM_HeLa_Curcumin_4h_R1 4 LDSSPSVSSTLAAK 14 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 LDS(0.071)S(0.911)PS(0.013)VS(0.001)S(0.004)TLAAK;LDS(0.341)S(0.65)PS(0.009)VSSTLAAK;LDS(0.139)S(0.861)PS(0.001)VSSTLAAK;LDS(0.079)S(0.906)PS(0.013)VS(0.001)S(0.001)TLAAK ;;; 211.82 6.27E-10 480711000 17645.4 14640 16185.9 16499.3 18131.3 16785.2 13386.1 7771.5 14145.1 12309.4 TRUE FALSE FALSE 16248.74797 15905.41637 16785.76369 16431.03027 17915.09609 13303.76031 13761.67794 10140.99457 12593.41792 12737.15073 1.275697235 1.248742101 1.317858605 1.290008308 1.406523049 1.044484798 1.080436137 0.796174497 0.988715466 1 13.63675497 -4.219187792 1.592522715 1.182390721 0.63256812 0.454451225 0.133879891 0.9957748 2.170212916 0.022269025 0.872631369 6.04E-05 4.219187792 -0.549822601 LDSS(ph)PVS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 LDSSPVSSPR 10 0 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 2 0 LDS(0.046)S(0.954)PVS(0.912)S(0.088)PR;LDS(0.059)S(0.941)PVS(0.727)S(0.273)PR ; 128.88 0.0073472 42022000 12127 9584.5 10010.6 11825.1 11001.6 13219.9 12416.7 3371.2 12907.2 10650.5 TRUE FALSE FALSE 11167.13515 10412.94147 10381.60164 11776.17087 10870.41311 10477.94372 12765.07918 4399.063361 11491.31245 11020.60408 1.013296102 0.944861225 0.942017476 1.068559471 0.986371802 0.950759472 1.158292149 0.399167172 1.042711667 1 13.42791569 -4.252429216 24.98879843 1.004741401 0.399166858 0.894110899 0.063213474 238.2643912 660788.8921 0.007649048 0.125505928 5.59E-05 4.252429216 -0.605574543 SLHPWYGIT(ph)PTS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 SLHPWYGITPTSSPK 15 0 Q8N3F8;H0Y6J8 Q8N3F8 MICALL1 MICAL-like protein 1 2 0 SLHPWY(0.001)GIT(0.991)PT(0.013)S(0.598)S(0.397)PK 169.4 0.00081818 10856000 1578.7 1123.6 1270.2 1481.7 1913.1 2210 980.48 192.69 2084.4 1326.6 TRUE FALSE FALSE 1453.744229 1220.718977 1317.274729 1475.569118 1890.287532 1751.621088 1007.98963 251.440294 1855.746535 1372.699251 1.059040593 0.889283633 0.959623696 1.074939843 1.377058762 1.27604141 0.734312071 0.183172165 1.351895933 1 10.42279986 -4.394515059 3.122472315 1.054746708 0.158011256 0.735748795 0.170654626 0.104012687 1.629216603 0.021261556 0.187751111 4.03E-05 4.394515059 -0.896735451 down LDSSEMDHS(ph)ENEDYTMSSPLPGKK ddPTM_HeLa_Curcumin_4h_R1 2 LDSSEMDHSENEDYTMSSPLPGKK 24 1 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 LDS(0.034)S(0.031)EMDHS(0.382)ENEDY(0.222)T(0.254)MS(0.071)S(0.005)PLPGKK;LDS(0.011)S(0.011)EMDHS(0.964)ENEDY(0.006)T(0.006)MS(0.002)SPLPGKK ; 71.434 0.0002387 40734000 6068.4 4813.4 5236.4 5714.5 6014.6 6966.1 4302 2666.4 6396.3 5401.2 TRUE FALSE FALSE 5588.079737 5229.448848 5430.46559 5690.854913 5942.879823 5521.252336 4422.702542 3479.373085 5694.641893 5588.891298 0.99985479 0.935686269 0.971653464 1.018243979 1.06333788 0.987897606 0.791338086 0.622551576 1.018921569 1 12.4483464 -4.550567818 2.420879775 0.999273545 0.620890745 0.935250282 0.032279806 0.059489622 0.604851993 0.004785412 0.035865616 2.81E-05 4.550567818 -0.378382799 LDSSEMDHSENEDY(ph)TMSSPLPGK ddPTM_HeLa_Curcumin_4h_R1 1 LDSSEMDHSENEDYTMSSPLPGK 23 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 LDS(0.004)S(0.003)EMDHS(0.047)ENEDY(0.902)T(0.042)MS(0.002)S(0.001)PLPGK 64.87 0.0053576 0 3000.1 2321.2 3127.2 2918.4 3848.2 4292.1 3011.3 2590.1 3757.9 3214.8 TRUE FALSE FALSE 2762.638919 2521.834185 3243.096783 2906.324434 3802.312728 3401.870078 3095.788974 3379.809567 3345.667772 3326.514061 0.830490678 0.758101165 0.974923516 0.873684698 1.143032213 1.022653149 0.93064058 1.016021428 1.005757893 1 11.69979542 -5.798084085 24.9980465 0.906291338 1.0207386 0.31667768 0.086749014 180.5640194 123175.4982 0.014167841 0.025681917 1.59E-06 5.798084085 0.114447262 LDSSEMDHSENEDYT(ph)MSSPLPGK ddPTM_HeLa_Curcumin_4h_R1 1 LDSSEMDHSENEDYTMSSPLPGK 23 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 LDSSEMDHS(0.028)ENEDY(0.368)T(0.43)MS(0.132)S(0.042)PLPGK 58.479 0.0025999 21278000 2432.7 2143.5 2600 2705.3 2825.3 2906.4 1477 1054.4 2779.7 2657.7 TRUE FALSE FALSE 2240.149228 2328.774589 2696.358287 2694.106185 2791.610143 2303.579878 1518.440645 1375.881706 2474.773864 2750.054877 0.814583464 0.846810225 0.980474357 0.979655427 1.015110704 0.837648695 0.552149216 0.500310637 0.899899811 1 11.42524469 -4.794354375 3.356017852 0.92208493 0.509171632 0.866583932 0.063049946 0.076424706 1.743919906 0.011868043 0.046050001 1.61E-05 4.794354375 -0.412913298 LDSSPS(ph)VSSTLAAKDDPDGK ddPTM_HeLa_Curcumin_4h_R1 1 LDSSPSVSSTLAAKDDPDGK 20 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 LDS(0.008)S(0.038)PS(0.944)VS(0.008)S(0.002)TLAAKDDPDGK 116.87 5.92E-05 41136000 6705.6 6280.8 6943.4 6095.7 6819 7166.9 5938 2824.4 6347.3 5387.9 TRUE FALSE FALSE 6174.844684 6823.684365 7200.728512 6070.477609 6737.687879 5680.404152 6104.604299 3685.546558 5651.01707 5575.129124 1.107569806 1.22395091 1.291580581 1.088849688 1.208525889 1.018882976 1.094970926 0.661069273 1.013611872 1 12.4447895 -4.261230731 24.09778701 1.092472164 0.661069073 0.666411254 0.095305829 5.403799719 623366.7099 0.014696942 0.114087383 5.48E-05 4.261230731 -0.431403091 LDSSPSVS(ph)STLAAKDDPDGK ddPTM_HeLa_Curcumin_4h_R1 1 LDSSPSVSSTLAAKDDPDGK 20 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 LDSS(0.001)PS(0.029)VS(0.714)S(0.217)T(0.038)LAAKDDPDGK 103.75 0.00016396 38354000 5842.3 5820.5 6687.4 6263.1 7856.1 7709.1 5614.6 3742.7 7808 5716.2 TRUE FALSE FALSE 5379.87579 6323.598084 6935.240927 6237.184952 7762.421138 6110.145761 5772.130565 4883.832001 6951.481935 5914.837525 0.909555971 1.069107656 1.17251588 1.054498103 1.312364221 1.033020051 0.975873055 0.825691658 1.175261688 1 12.53012282 -7.242378395 21.6520167 0.957290329 1.072210946 0 0.138297118 203.0157337 230611.4308 0.020673711 0.025281761 5.72E-08 7.242378395 0.114920617 LDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 LDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPK 35 3 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 LDSSPSVS(0.001)S(0.001)T(0.001)LAAKDDPDGKQEAKPQQAAGMLS(0.998)PK 46.149 0.0047351 15137000 878.6 600.6 625.99 696.19 776.92 840.29 615.5 363.71 649.66 901.11 TRUE FALSE FALSE 809.0578829 652.5131878 649.1897401 693.3093502 767.6557364 666.004382 632.7692735 474.6035047 578.3939234 932.4235054 0.867693573 0.699803452 0.696239141 0.743556277 0.823290846 0.714272407 0.678628616 0.508999936 0.620312465 1 9.864841564 -4.779540967 0.086440978 1.325066209 1.45E-19 0 0.13852195 19.8681105 0.334856395 1.501476237 4.058704825 1.66E-05 4.779540967 -1.325066209 LDT(ph)PDINIVLK ddPTM_HeLa_Curcumin_4h_R1 1 LDTPDINIVLK 11 0 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 0 LDT(1)PDINIVLK 152 0.0014429 38156000 4494.2 4178.7 5342.8 4324.3 3745.2 4659.2 4526.7 4089 3994.8 4456.6 TRUE FALSE FALSE 4138.479328 4539.888208 5540.808868 4306.407192 3700.540936 3692.8294 4653.707019 5335.717277 3556.580434 4611.466518 0.89743237 0.984478189 1.201528591 0.933847655 0.802465099 0.800792847 1.009159885 1.157054324 0.771247155 1 12.17100991 -6.035027722 24.98456892 0.974601233 0.928417428 0.007831695 0.138019125 2158.925748 1539916.386 0.019710157 0.032695354 9.23E-07 6.035027722 -0.046183805 LDTDDLDEIEK ddPTM_HeLa_Curcumin_4h_R1 2 LDTDDLDEIEK 11 0 I3L0H8;Q9NUU7;I3L352;F6QDS0;H3BQK0;Q9UMR2-3;Q9NUU7-2;Q9UMR2-2;Q9UMR2-4;Q9UMR2 I3L0H8 DDX19A;DDX19B ATP-dependent RNA helicase DDX19A;ATP-dependent RNA helicase DDX19B 0 0 ; ; 206.73 1.68E-06 38590000 3707.7 3402.8 3639.2 4116.2 3895.1 4018.3 3361.7 2877.2 3817.1 3253.2 FALSE FALSE TRUE 3414.231633 3696.922869 3774.071953 4099.168255 3848.653476 3184.859284 3456.020254 3754.445035 3398.37368 3366.248458 1.014254199 1.098232325 1.121150741 1.217725996 1.143306421 0.946115334 1.026668203 1.115320239 1.009543331 1 11.71692595 -7.289124575 5.239516167 1.006382987 1.094775461 0.261936803 0.067397919 0.206795137 16.44785295 0.012521088 0.014522843 5.14E-08 7.289124575 0.088392474 GGSDGT(ph)PRGS(ph)PSPASVSSGR ddPTM_HeLa_Curcumin_4h_R1 1 GGSDGTPRGSPSPASVSSGR 20 1 Q96II5;P10398 Q96II5 ARAF Serine/threonine-protein kinase A-Raf 2 0 GGS(0.002)DGT(0.998)PRGS(0.675)PS(0.024)PAS(0.21)VS(0.051)S(0.041)GR 76.068 0.016742 7336400 1920.3 1386.1 1887.6 2140.6 1917.8 1967.6 1197.3 170.2 1885.2 1784.1 TRUE FALSE FALSE 1768.306229 1505.908308 1957.556117 2131.742764 1894.931488 1559.497581 1230.893016 222.0931965 1678.398277 1846.097342 0.957861857 0.8157253 1.060375351 1.154729339 1.026452638 0.844753711 0.666754124 0.120304164 0.909160226 1 10.85026291 -4.39400071 1.706976782 0.987067919 7.43E-17 0.893926747 0.090539745 0.16061613 0.555647168 0.013009778 0.236260575 4.04E-05 4.39400071 -0.987067919 down LDVGNFSWGSECCTR ddPTM_HeLa_Curcumin_4h_R1 1 LDVGNFSWGSECCTR 15 0 P62241 P62241 RPS8 40S ribosomal protein S8 0 0 153.7 0.0034116 20537000 1195 720.61 952.63 913.34 994.43 1082.7 789.33 696.99 943.3 725.03 FALSE FALSE TRUE 1100.414489 782.8963174 987.9353058 909.5608411 982.5720717 858.1358155 811.4764754 909.4990425 839.82235 750.2247385 1.466779796 1.043549056 1.316852478 1.212384495 1.309703641 1.143838335 1.081644518 1.212302122 1.119427695 1 9.551179026 -5.052820932 22.09876255 1.223626612 1.138415038 0.03847366 0.133164022 248.8813017 104124.6775 0.025216601 0.064291865 8.85E-06 5.052820932 -0.085211574 LDVQFSGLTK ddPTM_HeLa_Curcumin_4h_R1 1 LDVQFSGLTK 10 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 96.113 0.014836 727180 514.22 415.99 702.11 691.25 747.12 466.68 458.04 476.36 666.9 571.01 FALSE FALSE TRUE 473.5189444 451.946322 728.1308142 688.3897907 738.211082 369.8853074 470.8913696 621.5999711 593.7427385 590.852555 0.801416429 0.76490542 1.232339283 1.165078808 1.24939983 0.626019646 0.796969338 1.052039068 1.004891548 1 9.206654346 -3.930301264 17.11414799 0.932522198 2.915690221 0.001827369 0.202922983 21077008.34 82131831.82 0.029179141 1523321119 0.000117408 3.930301264 1.983168023 LDVTILS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 LDVTILSPSR 10 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 1 0 LDVTILS(0.939)PS(0.061)R;LDVTILS(0.994)PS(0.006)R ; 141.89 0.0013956 139771000 6364.1 4726.9 5401.4 5756.5 5149.1 8496.8 8646.5 4870.7 5940.9 4706 TRUE FALSE FALSE 5860.37477 5135.472173 5601.580636 5732.681128 5087.700345 6734.467901 8889.097519 6355.754008 5289.198133 4869.53315 1.203477744 1.054612838 1.15033217 1.17725477 1.044802487 1.382980194 1.82545169 1.305208079 1.08618177 1 12.24956775 -5.071756746 4.263619929 1.10344416 1.575451314 0.674437079 0.131557152 0.086340636 2.98130348 0.018200893 0.050647323 8.48E-06 5.071756746 0.472007154 LDVTILSPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 LDVTILSPSR 10 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 1 0 LDVTILS(0.352)PS(0.648)R 160.72 0.00061062 117280000 2056.9 1804.6 1644.8 1747 1882.7 2955.2 2617.3 1673.4 2017 1732.1 TRUE FALSE FALSE 1894.094195 1960.581583 1705.757735 1739.771377 1860.250032 2342.258208 2690.734394 2183.611957 1795.740146 1792.290346 1.05680098 1.093897307 0.951719535 0.970697287 1.037917788 1.306851991 1.501282646 1.218336059 1.0019248 1 10.80758865 -5.22308499 4.039311198 1.022362246 1.367723608 0.800982081 0.07464353 0.063885182 2.3042278 0.009879019 0.025916599 5.98E-06 5.22308499 0.345361362 LDVTILSPSR ddPTM_HeLa_Curcumin_4h_R1 1 LDVTILSPSR 10 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 102.62 0.0083892 2153100 995.51 722.39 1016 645.64 913.19 956.07 619.09 854.38 829.37 925 FALSE FALSE TRUE 916.714333 784.8301727 1053.653854 642.9685128 902.3008057 757.7703049 636.4599992 1114.876529 738.390186 957.1436811 0.957760419 0.819971116 1.100831437 0.671757569 0.942701523 0.791699637 0.664957636 1.164795371 0.771451769 1 9.9025917 -7.112746829 0.755176393 0.989629514 0.851939625 0 0.168729754 0.900373083 1.05204161 0.034659886 0.045423448 7.71E-08 7.112746829 -0.137689889 LDVTILSPSRK ddPTM_HeLa_Curcumin_4h_R1 2 LDVTILSPSRK 11 1 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 119.27 0.00063038 15518800 6866.7 5397.6 5811.9 6811.7 5490.7 7377.4 6008.7 5588.7 6886.6 6904.6 FALSE FALSE TRUE 6323.193449 5864.144493 6027.294127 6783.51499 5425.226989 5847.24408 6177.28795 7292.668903 6131.157209 7144.534336 0.885039269 0.820787502 0.843623089 0.949469157 0.759353477 0.818422 0.864617295 1.020733971 0.858160507 1 12.80262427 -8.7677713 0.738054867 0.998296472 0.864177864 0 0.081105515 0.565208059 0.594972803 0.040605922 0.014961421 1.71E-09 8.7677713 -0.134118608 LDYVPS(ph)SASREVR ddPTM_HeLa_Curcumin_4h_R1 1 LDYVPSSASREVR 13 1 J3KPS2;A0A494C1T9;Q6ZRV2 J3KPS2 FAM83H Protein FAM83H 1 0 LDYVPS(0.366)S(0.366)AS(0.267)REVR 99.796 0.003124 7589700 2984.7 2472.6 2622.9 3064.8 2253.8 4240 2841.2 1096.7 4629.7 3395.6 TRUE FALSE FALSE 2748.457846 2686.320526 2720.106981 3052.11867 2226.924907 3360.576205 2920.916425 1431.078781 4121.833493 3513.596847 0.782234834 0.764550016 0.774165933 0.868659326 0.633802056 0.956449004 0.831318035 0.407297377 1.173109401 1 11.77873295 -13.52287875 0.134939778 1.850597306 0.655987922 0.450929747 0.146294588 65.92986744 0.625063428 15.02425206 0.426349647 3.00E-14 13.52287875 -1.194609384 LDYVPSSAS(ph)R ddPTM_HeLa_Curcumin_4h_R1 3 LDYVPSSASR 10 0 J3KPS2;A0A494C1T9;Q6ZRV2 J3KPS2 FAM83H Protein FAM83H 1 0 LDYVPSSAS(1)R;LDYVPS(0.007)S(0.052)AS(0.941)R;LDYVPSSAS(1)R ;; 136.81 0.0019569 98074000 7865.3 6173.7 6725.6 7810.1 8392.8 9894 8731.7 3244.7 7647 6881.3 TRUE FALSE FALSE 7242.753206 6707.327119 6974.856652 7777.783876 8292.721342 7841.872872 8976.688002 4233.994093 6808.143232 7120.424663 1.01717995 0.941984142 0.979556274 1.092320226 1.16463859 1.101320952 1.260695594 0.594626626 0.956142864 1 12.79774757 -6.265239527 23.63808057 1.000360103 1.064858948 0.019157387 0.166609952 470.3771412 2925899.667 0.023169349 0.036289458 5.43E-07 6.265239527 0.064498845 LDYWEDDLR ddPTM_HeLa_Curcumin_4h_R1 1 LDYWEDDLR 9 0 E9PEM5;A0A494C1L5;P50851-2;P50851;H0YAC6;A0A494BZW2;Q5T321;A0A0D9SF28;F5GXV7;Q8NFP9 E9PEM5 LRBA;NBEA Lipopolysaccharide-responsive and beige-like anchor protein;Neurobeachin 0 0 159.28 0.007278 1702600 1153.7 780.63 992.92 969.61 916.93 1042.5 826.36 704.49 1058.8 978.41 FALSE FALSE TRUE 1062.383428 848.1041788 1029.718489 965.5980107 905.9962086 826.2737486 849.5454376 919.2857579 942.652289 1012.409675 1.049361197 0.837708489 1.01709665 0.953762133 0.894890904 0.816145647 0.839132081 0.908017555 0.93109767 1 9.983577484 -6.184348285 0.703002297 1.020000971 0.846821925 0.267285877 0.065455605 0.410787063 0.391240586 0.012603442 0.033952821 6.54E-07 6.184348285 -0.173179046 LEAALGEAK ddPTM_HeLa_Curcumin_4h_R1 2 LEAALGEAK 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 138.98 0.00010397 10743900 10284.2 7193.3 8793 8393.8 8804.3 10363.3 8452.3 7572.6 9026.3 8678.7 FALSE FALSE TRUE 9470.194718 7815.056799 9118.876315 8359.06868 8699.314473 8213.834762 8689.44879 9881.45088 8036.137473 8980.284179 1.054554013 0.870246046 1.015432934 0.930824517 0.968712604 0.914651986 0.96761401 1.100349464 0.894864496 1 13.13254538 LEAALGEAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 LEAALGEAKK 10 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 1 ; LEAALGEAK(1)K;LEAALGEAK(1)K 157.24 3.46E-09 13246600 6216 7120.9 5039.1 5246.5 9409.5 12785.2 9303.9 8881.4 13511.3 6081 FALSE TRUE FALSE 5723.997041 7736.398866 5225.853479 5224.791373 9297.297858 10133.4054 9564.942394 11589.29798 12029.14419 6292.314297 0.909680726 1.229499752 0.83051374 0.830344946 1.477564123 1.610441711 1.520099274 1.841818038 1.911720176 1 12.61937502 -5.647581354 4.508919669 0.960969058 1.629176244 0.296349586 0.328093584 0.056241768 1.964149339 0.018721516 0.038272443 2.25E-06 5.647581354 0.668207187 LEADQS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 LEADQSPK 8 0 P49454 P49454 CENPF Centromere protein F 1 0 LEADQS(1)PK 96.171 0.017294 30342000 6698.4 6155.5 6244.2 6376.9 6308.3 7882.5 6878.7 3136 6084.7 5438.4 TRUE FALSE FALSE 6168.214572 6687.553992 6475.615545 6350.514077 6233.077643 6247.580646 7071.697809 4092.151964 5417.223633 5627.383995 1.096106926 1.18839482 1.150732836 1.128501997 1.107633253 1.110210473 1.256658123 0.727185486 0.962653986 1 12.4582487 -8.809642261 0.954317004 1.006698357 1.1061353 0.092822387 0.133473318 0.961802702 1.729810625 0.054906816 0.023902767 1.55E-09 8.809642261 0.099436943 LEAEIATYR ddPTM_HeLa_Curcumin_4h_R1 1 LEAEIATYR 9 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 "Keratin, type I cytoskeletal 18" 0 0 126.24 0.000877 3743200 1470.4 1278.5 1477.3 1233.3 1584.9 1751.1 1244.6 1063.8 1416.9 959.13 FALSE FALSE TRUE 1354.016288 1389.007843 1532.050038 1228.196931 1566.001103 1387.902121 1279.520126 1388.147723 1261.469615 992.4596961 1.364303552 1.399560958 1.543689929 1.237528271 1.57789894 1.398446835 1.289241398 1.398694303 1.271053746 1 9.954864705 -8.937799224 0.641185714 0.978650705 1.409198435 0.34627429 0.125744046 0.341149388 0.245926868 0.078673065 0.021410754 1.15E-09 8.937799224 0.43054773 LEAMCFDGVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 LEAMCFDGVKR 11 1 X6RAC9;P47813 X6RAC9 EIF1AX "Eukaryotic translation initiation factor 1A, X-chromosomal" 0 1 ; LEAMCFDGVK(1)R;LEAMCFDGVK(1)R 136.96 0.00010644 2649100 830.42 951.65 933.08 948.21 1065.57 1671.13 1267.4 1053.11 1831.65 1008.33 FALSE TRUE FALSE 764.6913807 1033.906386 967.6607656 944.2865583 1052.863774 1324.5188 1302.959833 1374.198391 1630.722578 1043.369392 0.732905706 0.990930339 0.927438329 0.905035709 1.009099731 1.269462963 1.24880013 1.317077538 1.562938868 1 10.0270343 -5.386409332 2.017219579 0.885736685 1.290910152 0.061853959 0.226089805 0.129232202 1.016222248 0.015654447 0.044172013 4.11E-06 5.386409332 0.405173467 LEAPLEELR ddPTM_HeLa_Curcumin_4h_R1 2 LEAPLEELR 9 0 F2Z3J2;Q16401-2;Q16401 F2Z3J2 PSMD5 26S proteasome non-ATPase regulatory subunit 5 0 0 ; ; 128.69 0.00069868 1871870 1197.69 732.07 1168.91 848.49 884.43 1451.38 1054.88 922.74 1159.09 1139.5 FALSE FALSE TRUE 1102.891573 795.3468688 1212.230833 844.9791732 873.8837499 1150.347428 1084.477094 1204.079178 1031.940727 1179.09754 0.935369242 0.674538655 1.028100553 0.716632123 0.741146275 0.97561685 0.919751807 1.021187084 0.875195386 1 10.20346735 -7.501738196 13.29618881 0.971514354 0.865078665 0.047955255 0.122451579 1.539035908 966.6300324 0.020289168 0.022004654 3.15E-08 7.501738196 -0.106435689 NSNS(ph)PPSPSSMNQR ddPTM_HeLa_Curcumin_4h_R1 1 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 0 NS(0.001)NS(0.999)PPSPSSMNQR 187.08 2.85E-05 32486000 2849.8 2846.3 2501.3 2554.7 2624.6 2514.8 1751.6 755.18 2951.8 2164.7 TRUE FALSE FALSE 2624.235323 3092.321489 2594.000378 2544.129328 2593.303359 1993.202132 1800.745182 985.4309056 2627.994925 2239.923164 1.171573813 1.38054802 1.158075607 1.135810982 1.157764427 0.889852904 0.803931675 0.439939602 1.173252265 1 11.12923353 -4.392342192 1.165161006 1.120476562 0.231805017 0.829779826 0.103324027 0.472894493 0.612418399 0.01852964 0.479486332 4.05E-05 4.392342192 -0.888671545 down RADNCS(ph)PVAEEETTGSAESTLPK ddPTM_HeLa_Curcumin_4h_R1 2 RADNCSPVAEEETTGSAESTLPK 23 1 Q9C0D5-2;Q9C0D5 Q9C0D5-2 TANC1 Protein TANC1 1 0 RADNCS(0.998)PVAEEET(0.002)TGSAESTLPK;RADNCS(1)PVAEEETTGSAESTLPK ; 116.1 2.09E-06 92646000 8488.5 7522 7061.9 7339.4 6682.3 6572.3 4622.4 2440 9303 8012.1 TRUE FALSE FALSE 7816.626268 8172.168163 7323.620226 7309.031507 6602.617937 5209.130895 4752.092103 3183.944768 8282.484175 8290.519879 0.942839096 0.985724452 0.883372856 0.88161317 0.796405778 0.628323793 0.573195912 0.384046455 0.999030736 1 13.01724686 -4.391615959 0.510398159 0.982627102 0.026580098 0.981873823 0.026977435 0.317577475 0.060228405 0.005692882 0.176274933 4.06E-05 4.391615959 -0.956047004 down GQS(ph)QLS(ph)NPTDDSWK ddPTM_HeLa_Curcumin_4h_R1 2 GQSQLSNPTDDSWK 14 0 Q9Y6D5 Q9Y6D5 ARFGEF2 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 2 0 GQS(0.856)QLS(0.823)NPT(0.222)DDS(0.099)WK;GQS(1)QLS(0.974)NPT(0.011)DDS(0.015)WK ; 121.79 0.0025547 5012900 6156.6 5704.9 5491 5774.4 5504.7 5877.6 3502.9 1256.93 5945.3 6076.9 TRUE FALSE FALSE 5669.298614 6198.006135 5694.50129 5750.507063 5439.060048 4658.519506 3601.181946 1640.162171 5293.115464 6288.071823 0.901595715 0.98567674 0.905603729 0.914510398 0.864980586 0.740850238 0.572700511 0.260837061 0.841770834 1 12.61840198 -4.390419813 0.893311189 0.951953227 2.00E-18 0.952944264 0.046569196 0.2167046 0.145532328 0.006344047 0.191656269 4.07E-05 4.390419813 -0.951953227 down LEDEDEDLGAPPGEEYGDGS(ph)PSREDSMVPPK ddPTM_HeLa_Curcumin_4h_R1 2 LEDEDEDLGAPPGEEYGDGSPSREDSMVPPK 31 1 A0A494BZV2;H0Y2S9 A0A494BZV2 MPRIP 1 0 LEDEDEDLGAPPGEEY(0.428)GDGS(0.485)PS(0.062)REDS(0.025)MVPPK;LEDEDEDLGAPPGEEY(0.429)GDGS(0.508)PS(0.055)REDS(0.009)MVPPK ; 70.027 4.50E-05 18706200 5231.1 3831.3 4376.5 4725.9 4564.1 5533.1 3827.9 2134.45 4734.3 4274.2 TRUE FALSE FALSE 4817.052915 4162.4605 4538.69694 4706.345478 4509.676088 4385.472689 3935.300572 2785.233979 4214.959135 4422.728132 1.089158721 0.941152243 1.026221103 1.064127239 1.019659349 0.991576366 0.889790296 0.629754734 0.953022435 1 12.11072085 -4.09639571 1.293574884 1.034887774 0.323822443 0.863253561 0.045659897 0.449815724 0.488312087 0.00651256 0.465389041 8.01E-05 4.09639571 -0.711065331 LEDFFAR ddPTM_HeLa_Curcumin_4h_R1 1 LEDFFAR 7 0 P11413;P11413-3;P11413-2;E9PD92;E7EM57;E7EUI8 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 0 107.43 0.015585 614540 509.51 487.7 666.19 799.91 635.93 787.6 446.27 502.07 812.97 757.03 FALSE FALSE TRUE 469.1817459 529.8546149 690.8795874 796.6001844 628.3469501 624.2428819 458.7911351 655.1488318 723.789225 783.3367362 0.598952818 0.676407208 0.88197011 1.016931988 0.802141558 0.796902345 0.585688267 0.836356578 0.923982231 1 9.613488808 -9.606706955 1.431478569 0.999051429 0.752828174 0.242876455 0.126299616 0.42070379 1.556831752 0.097726384 0.022906004 2.47E-10 9.606706955 -0.246223255 LEDNDSAAS(ph)DPDAETTAR ddPTM_HeLa_Curcumin_4h_R1 2 LEDNDSAASDPDAETTAR 18 0 Q9BYV8-5;Q9BYV8-2;Q9BYV8;F8WF85;C9J6R3;C9J9X8;C9JCX6;C9JXA0 Q9BYV8-5 CEP41 Centrosomal protein of 41 kDa 1 0 LEDNDS(0.003)AAS(0.997)DPDAETTAR;LEDNDS(0.171)AAS(0.829)DPDAETTAR ; 152.86 6.35E-05 25118000 3183.9 2272.59 2332.55 2490.26 2495.6 3289.2 2587.32 1794.5 2904 2503.8 TRUE FALSE FALSE 2931.890955 2469.022553 2418.996355 2479.955964 2465.8416 2606.982843 2659.913236 2341.634789 2585.438465 2590.806864 1.131651686 0.952993675 0.933684556 0.957213754 0.95176589 1.006243607 1.026673687 0.903824527 0.997927905 1 11.33918576 -7.237346055 24.66778571 1.062168854 0.964337707 0.353507825 0.048374127 501.1084478 513056.9951 0.009567383 0.011714669 5.79E-08 7.237346055 -0.097831147 LEDNPSSGS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 1 LEDNPSSGSPPR 12 0 Q05D32;H0YMH7;Q05D32-2 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 0 LEDNPS(0.024)S(0.205)GS(0.771)PPR 128.21 0.0027017 36180000 1862.7 1498.4 1875 1774.4 2146.6 2302.2 2104.6 1069.9 1779.7 1530.7 TRUE FALSE FALSE 1715.265329 1627.915019 1944.489149 1767.058003 2121.003197 1824.697769 2163.649412 1396.107585 1584.471363 1583.891711 1.082943561 1.027794393 1.227665462 1.115643191 1.339108717 1.15203442 1.366033673 0.88144131 1.000365967 1 10.62925799 -6.76702802 24.99999996 1.039409172 1.191754564 0.251636716 0.127337586 132.0336347 590633.9756 0.018486921 0.024678995 1.71E-07 6.76702802 0.152345393 LEDTENWLYEDGEDQPK ddPTM_HeLa_Curcumin_4h_R1 2 LEDTENWLYEDGEDQPK 17 0 P34932;A0A087WYC1 P34932 HSPA4 Heat shock 70 kDa protein 4 0 0 ; ; 171.76 0.0001488 15571000 2675.28 2062.91 2532.4 2540.4 2586.9 2668.1 2436 1984.23 2563.2 2404.02 FALSE FALSE TRUE 2463.528765 2241.218748 2626.252972 2529.888498 2556.052907 2114.705984 2504.347604 2589.212593 2282.023373 2487.559516 0.990339628 0.900970905 1.055754829 1.017016269 1.027534373 0.850112719 1.006748819 1.040864581 0.917374382 1 11.28051533 KRS(ph)VAVS(ph)DEEEVEEEAER ddPTM_HeLa_Curcumin_4h_R1 1 KRSVAVSDEEEVEEEAER 18 2 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 2 0 KRS(1)VAVS(1)DEEEVEEEAER 77.584 0.0056624 11896000 2250.8 2291 1830.5 1879 2387.5 2564.9 4143 9032.7 2286 2604.2 TRUE FALSE FALSE 2072.646805 2489.023832 1898.33994 1871.225196 2359.030622 2032.910828 4259.24143 11786.72865 2035.231519 2694.695756 0.769158002 0.923675271 0.704472828 0.694410563 0.875434867 0.754412005 1.580601973 4.374048024 0.755273212 1 11.39590668 -4.257233919 2.551839463 0.855807436 5.149862252 0.989844 0.108097777 0.039740522 0.321985887 0.017771404 0.368258361 5.53E-05 4.257233919 4.294054816 up LEEFS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 LEEFSPR 7 0 Q9UGU0-2;Q9UGU0;I3L1M7 Q9UGU0-2 TCF20 Transcription factor 20 1 0 LEEFS(1)PR 107.69 0.016659 5162200 3634.4 2478.4 3213.4 3188.5 2912.3 4460.8 3336 2033.1 3691.5 2937.1 TRUE FALSE FALSE 3346.733405 2692.621852 3332.491431 3175.306832 2877.572725 3535.579796 3429.599182 2652.982831 3286.551686 3039.164006 1.101201975 0.885974514 1.096515826 1.044796143 0.946830352 1.163339586 1.128467952 0.872931775 1.081399911 1 11.56945882 -5.280096069 24.9937721 1.034062939 1.062268624 0.011881044 0.095869772 3405.925742 4562810.285 0.013263457 0.029703061 5.25E-06 5.280096069 0.028205685 LEEPEEPK ddPTM_HeLa_Curcumin_4h_R1 2 LEEPEEPK 8 0 O75822-2;O75822;O75822-3 O75822-2 EIF3J Eukaryotic translation initiation factor 3 subunit J 0 0 ; ; 128.1 0.0018484 4430500 3560.6 2869.6 3134.1 2881.2 3462.5 4129.7 2997.5 2835 3627 3100.1 FALSE FALSE TRUE 3278.774753 3117.635437 3250.252503 2869.278358 3421.211949 3273.153669 3081.601783 3699.378449 3229.127174 3207.828244 1.022116679 0.97188353 1.013225228 0.894461342 1.066519679 1.020364377 0.960650492 1.153234577 1.006639673 1 11.64738118 -4.251504092 24.8713487 1.002431139 1.153234665 0.533038096 0.043923633 762.060618 1907651.709 0.005628675 0.100894791 5.60E-05 4.251504092 0.150803526 LEEPEEPKVLT(ph)PEEQLADK ddPTM_HeLa_Curcumin_4h_R1 1 LEEPEEPKVLTPEEQLADK 19 1 O75822-2;O75822;O75822-3 O75822-2 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 0 LEEPEEPKVLT(1)PEEQLADK 76.586 0.0049665 12678000 3703.4 3223.2 2846.1 3732.3 3502.4 4590.9 4071.6 3850 3236.5 3042 TRUE FALSE FALSE 3410.271982 3501.799046 2951.57897 3716.856732 3460.636167 3638.69559 4185.838138 5023.847277 2881.464047 3147.709274 1.083413901 1.112491257 0.9376911 1.180813223 1.099414167 1.155982104 1.329804558 1.59603281 0.915416195 1 11.62008658 -1.00000002 0.565000659 1.039205483 29.45166539 0.864773188 0.070011507 27.18615631 0.216967709 0.010527271 946.389082 0.099999995 1.00000002 28.41245991 LEEPEEPKVLT(ph)PEEQLADKLR ddPTM_HeLa_Curcumin_4h_R1 3 LEEPEEPKVLTPEEQLADKLR 21 2 O75822-2;O75822;O75822-3 O75822-2 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 0 LEEPEEPKVLT(1)PEEQLADKLR;LEEPEEPKVLT(1)PEEQLADKLR;LEEPEEPKVLT(1)PEEQLADKLR ;; 67.217 0.0016686 53978000 10095.3 8485.5 8586 10174.1 8242.2 13123.2 11260.1 9954.9 12798.7 10029.7 TRUE FALSE FALSE 9296.246352 9218.948809 8904.204713 10132.00227 8143.917148 10401.30039 11576.0281 12990.10318 11394.71463 10378.23133 0.895744762 0.888296716 0.857969381 0.976274468 0.784711469 1.002222832 1.115414345 1.251668302 1.097943789 1 13.34127298 -4.63239817 2.208436495 0.929533091 1.24468699 0.617596257 0.081805806 0.147971134 1.277471683 0.009893122 0.067323416 2.33E-05 4.63239817 0.315153898 LEEPPELNRQS(ph)PNPR ddPTM_HeLa_Curcumin_4h_R1 3 LEEPPELNRQSPNPR 15 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 0 LEEPPELNRQS(1)PNPR;LEEPPELNRQS(1)PNPR;LEEPPELNRQS(1)PNPR ;; 86.262 0.0046888 2280081000 9709.4 7829.4 8817 8445.4 8746.2 10031 8169.6 2979.19 9302.2 7651.5 TRUE FALSE FALSE 8940.890745 8506.138449 9143.765776 8410.455173 8641.907277 7950.457527 8398.816989 3887.531316 8281.771933 7917.389055 1.129272628 1.074361559 1.154896609 1.062276353 1.091509741 1.004176689 1.060806401 0.491011783 1.046023111 1 12.95080903 -4.261044312 6.945803439 1.067934349 0.482129056 0.934438028 0.045952448 0.023830795 8.442689035 0.007890405 0.064922621 5.48E-05 4.261044312 -0.585805293 LEEPTPAPSTSYS(ph)PQADSLR ddPTM_HeLa_Curcumin_4h_R1 1 LEEPTPAPSTSYSPQADSLR 20 0 G3V1L9;Q07157 G3V1L9 TJP1 Tight junction protein ZO-1 1 0 LEEPTPAPS(0.013)T(0.048)S(0.26)YS(0.679)PQADSLR 151.28 2.53E-05 49908000 2729.7 1868.2 2537.6 2315.4 1959.4 1775.4 1169.2 833.94 2374.4 1939.6 TRUE FALSE FALSE 2513.641365 2029.678883 2631.645688 2305.819488 1936.035435 1407.162027 1202.004605 1088.204467 2113.93426 2007.000956 1.252436556 1.011299411 1.311232902 1.148888087 0.964641013 0.701126735 0.598905846 0.54220426 1.053280146 1 10.97082559 -5.280359985 1.924081516 1.130857088 0.569616567 0.859104797 0.094173416 0.107843635 0.762586652 0.016881293 0.0531939 5.24E-06 5.280359985 -0.561240521 ATQVGEK(ac)TPKDESANQEEPEAR ddPTM_HeLa_Curcumin_4h_R1 2 ATQVGEKTPKDESANQEEPEAR 22 2 P50552;K7EM16 P50552 VASP Vasodilator-stimulated phosphoprotein 0 1 ; ATQVGEK(0.997)TPK(0.003)DESANQEEPEAR;ATQVGEK(1)TPKDESANQEEPEAR 176.48 7.44E-09 7398700 1319.97 1026.71 937.93 967.95 1060.3 1854.94 1464.89 2572.4 1789.4 1277.81 FALSE TRUE FALSE 1215.492982 1115.454237 972.6905109 963.9448794 1047.656615 1470.204535 1505.990871 3356.712918 1593.107297 1322.213802 0.91928626 0.843626224 0.73565297 0.729038585 0.792350385 1.111926477 1.138991945 2.538706609 1.204878737 1 10.36873976 -4.082452248 1.884905516 0.912572913 3.690969067 0.914578467 0.147759924 0.260083436 0.63366157 0.018792708 1.475225723 8.27E-05 4.082452248 2.778396154 up LEFQQQLGEAPSDAS(ph)P ddPTM_HeLa_Curcumin_4h_R1 2 LEFQQQLGEAPSDASP 16 0 Q9BUW7 Q9BUW7 C9orf16 UPF0184 protein C9orf16 1 0 LEFQQQLGEAPSDAS(1)P;LEFQQQLGEAPSDAS(1)P ; 156.17 0.0003018 39958000 7689.3 6736.6 7259.5 6553.1 6658.5 9699.2 7141.4 6271.8 8440.3 7188.2 TRUE FALSE FALSE 7080.683791 7318.881686 7528.543456 6525.985009 6579.101736 7687.476587 7341.768464 8184.042948 7514.420207 7437.989415 0.951962069 0.983986569 1.012174532 0.877385627 0.884526902 1.033542287 0.987063581 1.100303118 1.010275733 1 12.86069698 -3.979380565 1.447957793 0.968673612 1.238732126 0.390551299 0.049385298 1.976840397 2.192860976 0.00723567 0.934520418 0.000104862 3.979380565 0.270058514 LEGDS(ph)DVDSELEDRVDGVK ddPTM_HeLa_Curcumin_4h_R1 2 LEGDSDVDSELEDRVDGVK 19 1 Q92614;Q92614-2 Q92614 MYO18A Unconventional myosin-XVIIIa 1 0 LEGDS(0.985)DVDS(0.015)ELEDRVDGVK;LEGDS(0.76)DVDS(0.24)ELEDRVDGVK ; 122.53 8.72E-05 26461000 3625.6 3070.4 3222.1 3528.3 4023.5 4351.6 3205.3 4962.4 3578.3 3578.1 TRUE FALSE FALSE 3338.629934 3335.791695 3341.51386 3513.700829 3975.52239 3449.029107 3295.232091 6475.412916 3185.769442 3702.438709 0.90173807 0.900971483 0.902516996 0.949023362 1.073757786 0.931556031 0.890016649 1.748958842 0.860451636 1 11.85426014 -4.258878702 24.99997566 0.948877292 1.748959124 0.942281949 0.060381091 38.20745876 372998.4458 0.008240402 0.075127621 5.51E-05 4.258878702 0.800081832 LEGDSDDLLEDS(ph)DSEEHSR ddPTM_HeLa_Curcumin_4h_R1 3 LEGDSDDLLEDSDSEEHSR 19 0 A0A3B3IUB9;Q9NR09 A0A3B3IUB9 BIRC6 Baculoviral IAP repeat-containing protein 6 1 0 LEGDS(0.001)DDLLEDS(0.975)DS(0.024)EEHSR;LEGDSDDLLEDS(0.978)DS(0.022)EEHSR;LEGDS(0.005)DDLLEDS(0.705)DS(0.289)EEHS(0.001)R ;; 329.08 9.78E-210 56534000 5951.31 5750.35 5797.78 5767.2 7429.1 6720.81 5438.81 3998.19 5158.3 5331.31 TRUE FALSE FALSE 5480.257534 6247.384631 6012.650827 5743.336855 7340.512835 5326.838247 5591.408371 5217.219726 4592.447395 5516.572626 0.993417092 1.132475734 1.089925074 1.041105999 1.330629239 0.965606475 1.013565623 0.945735709 0.832481997 1 12.4295565 -7.290127532 23.59644639 0.996891391 1.076844769 0.175557309 0.113828685 565.9862222 465530.9765 0.017021842 0.019467771 5.13E-08 7.290127532 0.079953377 LEGGEVDLK(ac)GPK ddPTM_HeLa_Curcumin_4h_R1 2 LEGGEVDLKGPK 12 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 1 ; LEGGEVDLK(1)GPK;LEGGEVDLK(1)GPK 191.53 5.45E-14 3692700 2481.5 2770.8 2126.9 2365.5 3737.9 5306.4 3741.2 3863.7 6073.5 2291.1 FALSE TRUE FALSE 2285.086657 3010.295606 2205.724785 2355.712188 3693.327984 4205.792825 3846.168003 5041.724344 5407.252245 2370.715554 0.963880569 1.269783547 0.930404654 0.993671376 1.557895875 1.774060501 1.62236587 2.126667762 2.280852393 1 11.21110686 -5.614035578 2.542840713 1.000155459 1.819684552 0.170474731 0.431448534 0.068369202 0.891885053 0.020897757 0.047160815 2.43E-06 5.614035578 0.819529094 LEGGRQDS(ph)EDEEER ddPTM_HeLa_Curcumin_4h_R1 1 LEGGRQDSEDEEER 14 1 A0A3B3ISZ4;Q9BYE7-3;Q9BYE7 A0A3B3ISZ4 PCGF6 Polycomb group RING finger protein 6 1 0 LEGGRQDS(1)EDEEER 88.637 0.0049045 28904000 1563.9 1427.7 1301.9 1400 1489.6 1803.4 1107 1234.5 1423.8 1193.8 TRUE FALSE FALSE 1440.115665 1551.104026 1350.149559 1394.207171 1471.837493 1429.354511 1138.059441 1610.893367 1267.612702 1235.284461 1.165817032 1.255665456 1.092986759 1.128652723 1.191496808 1.157105555 0.921293416 1.304066729 1.026170685 1 10.27062759 -9.207798493 0.969542605 1.000786224 1.146523892 0.244058874 0.096887658 0.595519615 1.014438286 0.059056455 0.016920374 6.20E-10 9.207798493 0.145737668 LEGGSGGDSEVQR ddPTM_HeLa_Curcumin_4h_R1 2 LEGGSGGDSEVQR 13 0 P62195;J3QQM1;P62195-2 P62195 PSMC5 26S protease regulatory subunit 8 0 0 ; ; 160.77 6.06E-05 3543800 1683.44 1412.25 1291.92 1329.04 1373.89 1762.83 1536.48 1198.52 1623.4 1621.79 FALSE FALSE TRUE 1550.193948 1534.318597 1339.799692 1323.540785 1357.507259 1397.199187 1579.589494 1563.943231 1445.317082 1678.147082 0.923753326 0.914293278 0.798380372 0.788691765 0.808932229 0.832584463 0.941269994 0.931946459 0.861257691 1 10.71265345 -7.667101287 0.98249342 0.980754149 0.852317292 0.111386665 0.064344459 0.303230034 0.610429069 0.014575509 0.013964834 2.15E-08 7.667101287 -0.128436856 LEGNSPQGS(ph)NQGVK ddPTM_HeLa_Curcumin_4h_R1 1 LEGNSPQGSNQGVK 14 0 P61006 P61006 RAB8A Ras-related protein Rab-8A 1 0 LEGNS(0.273)PQGS(0.727)NQGVK 142.19 0.000712 3572500 599.77 564.78 597.4 722.74 910.47 820.43 768.12 695.83 976.62 686.46 TRUE FALSE FALSE 552.2975716 613.5970666 619.5401695 719.7494934 899.6132399 650.2635698 789.6713799 907.9853638 869.4872294 710.3144339 0.777539559 0.863838657 0.872205519 1.013282934 1.266500013 0.915458759 1.111720869 1.278286517 1.224087795 1 9.472313992 -6.040161742 4.470047214 0.888886914 1.126858829 0.226816224 0.150363948 0.14422554 6.504755462 0.018348884 0.031888153 9.12E-07 6.040161742 0.237971915 LEGPVS(ph)PDVEPGKEETEESK ddPTM_HeLa_Curcumin_4h_R1 1 LEGPVSPDVEPGKEETEESK 20 1 O14686;O14686-3;A0A3B3ISC8 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 0 LEGPVS(1)PDVEPGKEETEESK 94.359 0.00038693 44491000 4163.8 3175.7 4013 4023.5 4810.6 4412.5 3959.3 2182.3 3949.5 3263.5 TRUE FALSE FALSE 3834.230836 3450.193357 4161.72531 4006.851823 4753.236737 3497.297761 4070.387302 2847.673224 3516.249731 3376.906382 1.135427046 1.021702401 1.232407665 1.18654513 1.407571368 1.035651382 1.20535983 0.8432787 1.04126361 1 11.72148647 -8.946395759 0.614320868 0.9914706 1.147789806 0.08731136 0.141833601 1.505360571 0.979747904 0.124031033 0.03229995 1.13E-09 8.946395759 0.156319206 LEGPVS(ph)PDVEPGKEETEESKK ddPTM_HeLa_Curcumin_4h_R1 1 LEGPVSPDVEPGKEETEESKK 21 2 O14686;O14686-3;A0A3B3ISC8 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 0 LEGPVS(0.978)PDVEPGKEET(0.009)EES(0.012)KK 56.947 0.0114 6724700 1980.7 1474.1 1768.2 1518.5 2040.5 2132.8 1705.6 984.03 1937.8 1739.6 TRUE FALSE FALSE 1823.925505 1601.514636 1833.731047 1512.216849 2016.16837 1690.433238 1753.454546 1284.056217 1725.228188 1800.050971 1.013263255 0.889705159 1.018710624 0.840096683 1.120061822 0.939102984 0.97411383 0.713344365 0.958432965 1 10.81382204 -4.224961776 3.197931346 0.991126494 0.65943143 0.511371176 0.074150769 0.222081271 3.234327923 0.009230536 0.190241891 5.96E-05 4.224961776 -0.331695064 LEGVDGGQS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 LEGVDGGQSPR 11 0 O00418;H3BRH4 O00418 EEF2K Eukaryotic elongation factor 2 kinase 1 0 LEGVDGGQS(1)PR 133.98 0.0022497 267260000 3180.7 2588.7 2685.3 2788.8 2905.9 2877.3 1936.5 1898.4 3166.4 2493.1 TRUE FALSE FALSE 2928.944239 2812.455693 2784.81958 2777.260685 2871.24904 2280.515546 1990.832978 2477.213421 2819.053842 2579.735039 1.135366305 1.090211068 1.079498296 1.076568191 1.113001528 0.88401154 0.771719943 0.960258857 1.092768753 1 11.33300718 -5.208321075 6.07886248 1.072293423 0.859342554 0.756628502 0.054718669 0.093959096 7.976860056 0.00900655 0.023159185 6.19E-06 5.208321075 -0.212950868 LEHEYIHNFK ddPTM_HeLa_Curcumin_4h_R1 1 LEHEYIHNFK 10 0 Q15555-2;Q15555;K7EL66;K7ERD8;Q15555-4;Q15555-5;Q15555-3;K7ENB3;M0QX52;C9JB30;Q9UPY8;Q9UPY8-2 Q15555-2;C9JB30;Q9UPY8-2 MAPRE2;MAPRE3 Microtubule-associated protein RP/EB family member 2;Microtubule-associated protein RP/EB family member 3 0 0 72.643 0.011922 9458900 1698.2 1385.2 1244.8 1519.2 1610.6 1379.9 1128.4 1155.3 1818.5 1418.1 FALSE FALSE TRUE 1563.785678 1504.930516 1290.933383 1512.913953 1591.394647 1093.693185 1160.059867 1507.545652 1619.0151 1467.378869 1.065700012 1.025590968 0.87975465 1.031031579 1.084515172 0.745337968 0.790566016 1.02737315 1.103338159 1 10.5190257 -5.269730733 24.99801654 1.022724126 0.84803974 0.440570832 0.088999406 388.5482988 1171454.399 0.011974794 0.027203078 5.37E-06 5.269730733 -0.174684386 LEKPAK(ac)YDDIK ddPTM_HeLa_Curcumin_4h_R1 1 LEKPAKYDDIK 11 2 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 1 LEK(0.003)PAK(0.997)YDDIK 84.169 0.0078605 7073500 3049.9 3312.8 2681.2 2686.5 4343.4 6537.5 4594.9 4176.3 6928.4 2911.4 FALSE TRUE FALSE 2808.497197 3599.14367 2780.567631 2675.383975 4291.607792 5181.548807 4723.820527 5449.634645 6168.371854 3012.570933 0.932259276 1.194708357 0.922988269 0.888073355 1.424566554 1.719975702 1.568036283 1.808964756 2.047544105 1 11.5567795 -5.588357433 3.447944402 0.977578128 1.678223226 0.22544411 0.35247865 0.045353273 1.09005807 0.014160166 0.03048913 2.58E-06 5.588357433 0.700645098 LEKPLNCDDEVYDLMR ddPTM_HeLa_Curcumin_4h_R1 1 LEKPLNCDDEVYDLMR 16 1 Q02763-3;Q02763-2;Q02763 Q02763-3 TEK Angiopoietin-1 receptor 0 0 91.845 0.0043342 22856000 289.91 496.54 325.72 283.4 329.59 320.9 352.92 246.2 368.28 273.75 FALSE FALSE TRUE 266.9633176 539.4587051 337.7914697 282.2273659 325.6598545 254.3417227 362.8219854 321.2652466 327.8806054 283.2627921 0.942458117 1.904446048 1.192502083 0.996344644 1.149673955 0.897900218 1.28086708 1.134159712 1.157513851 1 8.145997299 LEKVPDS(ph)PENELK ddPTM_HeLa_Curcumin_4h_R1 2 LEKVPDSPENELK 13 1 A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;A0A0U1RR46;A0A0X1KG69;A0A087WUZ6 A0A2R8Y549 INADL InaD-like protein 1 0 LEKVPDS(1)PENELK;LEKVPDS(1)PENELK ; 116.87 0.0012221 28903000 11390.1 9284.5 10170.4 10627.9 10049.8 13057.8 8828.3 8332.3 11284.2 10540.1 TRUE FALSE FALSE 10488.56157 10087.01081 10547.32397 10583.92457 9929.962699 10349.46509 9075.998338 10872.77991 10046.35149 10906.36769 0.961691542 0.924873532 0.967079441 0.970435333 0.910473861 0.948937848 0.832174249 0.996920352 0.921145497 1 13.41288308 -7.585828047 0.238031316 1.017051134 0.904511208 0 0.048472849 1.831950611 0.408238102 0.081879706 0.06949077 2.60E-08 7.585828047 -0.112539926 LELQGPRGS(ph)PNAR ddPTM_HeLa_Curcumin_4h_R1 1 LELQGPRGSPNAR 13 1 P19338;H7BY16 P19338 NCL Nucleolin 1 0 LELQGPRGS(1)PNAR 129.17 0.016315 1387900000 5423.6 3631.8 3599.5 4260.9 3209.6 5457.8 3757.7 2843 5520.3 4468.5 TRUE FALSE FALSE 4994.316337 3945.716609 3732.900636 4243.269525 3171.327616 4325.790758 3863.130949 3709.817612 4914.736901 4623.780042 1.080137094 0.853353008 0.807326603 0.917705749 0.685873374 0.935552885 0.835491938 0.802334362 1.062926189 1 12.17485705 -7.215674848 6.70863904 1.03781091 0.833766181 0.679584546 0.067179 0.095921652 11.31097783 0.010815399 0.013204673 6.09E-08 7.215674848 -0.204044729 LELQGPRGSPNAR ddPTM_HeLa_Curcumin_4h_R1 1 LELQGPRGSPNAR 13 1 P19338;H7BY16 P19338 NCL Nucleolin 0 0 85.973 0.014088 7946700 1824.7 1606.6 1367.9 1414.6 1350.7 2006.9 1417.2 1214.5 2006.5 1620.7 FALSE FALSE TRUE 1680.27307 1745.467345 1418.595577 1408.74676 1334.593785 1590.646318 1456.962818 1584.795459 1786.39197 1677.019204 1.001940267 1.040815359 0.845903001 0.840030189 0.79581306 0.948496185 0.868781236 0.945007341 1.065218553 1 10.71168349 -6.758606575 24.99999905 1.003934275 0.872055159 0.693877573 0.048819884 31.86886813 281246.0217 0.006990025 0.009636206 1.74E-07 6.758606575 -0.131879115 LELSSSAS(ph)PQEER ddPTM_HeLa_Curcumin_4h_R1 4 LELSSSASPQEER 13 0 A0A075B6T1;Q9C0C7-6;Q9C0C7-4;Q9C0C7-2;Q9C0C7-3;Q9C0C7;Q9C0C7-5 A0A075B6T1 AMBRA1 Activating molecule in BECN1-regulated autophagy protein 1 1 0 LELSSS(0.001)AS(0.999)PQEER;LELSS(0.001)S(0.019)AS(0.981)PQEER;LELSSS(0.005)AS(0.995)PQEER;LELSS(0.001)S(0.006)AS(0.993)PQEER ;;; 201.3 3.74E-09 30403900 5153.8 3880.1 4126.62 4177.79 5030.8 5696.2 4275.57 3714.83 5423.1 4409.96 TRUE FALSE FALSE 4745.871292 4215.478555 4279.556167 4160.503412 4970.810996 4514.743911 4395.530987 4847.464566 4828.199498 4563.205782 1.040030084 0.923797601 0.937839837 0.911750118 1.089324311 0.989379863 0.963255044 1.062293659 1.058071831 1 12.155832 -7.345160244 24.9999998 1.018903088 0.981703797 0.132004334 0.055663987 165.4325867 49397.8163 0.009402248 0.010751878 4.52E-08 7.345160244 -0.037199292 LELSVLYK ddPTM_HeLa_Curcumin_4h_R1 1 LELSVLYK 8 0 J3KR44;F5GYJ8;Q96FW1;F5GYN4;F5H6Q1 J3KR44 OTUB1 Ubiquitin thioesterase OTUB1 0 0 101.6 0.011953 683050 686.14 459.96 683.92 546.24 931.94 729.82 670.22 749.53 452.83 749.53 FALSE FALSE TRUE 631.831295 499.7168929 709.2666768 543.9798036 920.8272242 578.4471052 689.0245694 978.0582466 403.1556819 775.5761117 0.814660593 0.644317025 0.914502995 0.701388033 1.187281571 0.745828935 0.888403548 1.261073197 0.519814465 1 9.599124558 -4.261780927 8.527550883 0.884964203 1.263271099 0.280786495 0.188348056 0.072512437 83.88172777 0.020347221 0.158900053 5.47E-05 4.261780927 0.378306897 LENEGS(ph)DEDIETDVLYSPQMALK ddPTM_HeLa_Curcumin_4h_R1 2 LENEGSDEDIETDVLYSPQMALK 23 0 O60502-3;O60502 O60502-3 MGEA5 Protein O-GlcNAcase 1 0 LENEGS(1)DEDIETDVLYSPQMALK;LENEGS(1)DEDIETDVLYSPQMALK ; 133.13 3.32E-06 51896000 9858.9 6832.4 7124.5 7866 8014.7 8870.3 7450.9 6333.5 8095.4 7427.1 TRUE FALSE FALSE 9078.557662 7422.962211 7388.540237 7833.452576 7919.129937 7030.499791 7659.952201 8264.554994 7207.354874 7685.191172 1.181305378 0.965878668 0.961399667 1.01929183 1.030440201 0.914811308 0.996715895 1.075387041 0.937823759 1 12.90786543 -7.228197729 24.87679012 1.085616448 0.992862792 0 0.074212531 641.2158315 479862.0505 0.012789004 0.015662933 5.91E-08 7.228197729 -0.092753656 LENS(ph)PLGEALR ddPTM_HeLa_Curcumin_4h_R1 2 LENSPLGEALR 11 0 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 0 LENS(1)PLGEALR;LENS(1)PLGEALR ; 143.93 0.0010885 65324000 6790.3 5103.7 6151.5 5579.1 4932.8 4945.6 2853.6 2677 6974.9 4941.8 TRUE FALSE FALSE 6252.84059 5544.841086 6379.480001 5556.015162 4873.979582 3919.826812 2933.664336 3493.204977 6209.77092 5113.527182 1.222803823 1.084347631 1.247569393 1.08653283 0.953154136 0.766560277 0.573706608 0.683130225 1.214381131 1 12.32010305 -5.309110088 1.777175405 1.117021194 0.626723051 0.876138186 0.079284128 0.110929734 0.667033487 0.01437021 0.046137655 4.91E-06 5.309110088 -0.490298143 LENSALLTVEPS(ph)PQDKNK ddPTM_HeLa_Curcumin_4h_R1 1 LENSALLTVEPSPQDKNK 18 1 O75509 O75509 TNFRSF21 Tumor necrosis factor receptor superfamily member 21 1 0 LENSALLTVEPS(1)PQDKNK 69.152 0.0067648 0 879.67 745.34 781.39 880.95 723.94 1069.3 803.15 529.02 1009.6 1005.3 TRUE FALSE FALSE 810.0431913 809.7638684 810.3490008 877.3048623 715.3074883 847.5151265 825.6842274 690.3157627 898.8494059 1040.2341 0.778712399 0.778443879 0.77900638 0.843372528 0.687640876 0.814734997 0.793748472 0.663615779 0.864083773 1 10.02269252 -9.588957199 0.403770009 1.103753747 0.755315521 0.446202064 0.066071251 1.01872966 0.180214172 0.156302624 0.015753634 2.58E-10 9.588957199 -0.348438226 LENVSQLSLDKS(ph)PTEK ddPTM_HeLa_Curcumin_4h_R1 2 LENVSQLSLDKSPTEK 16 1 Q86W56-3;Q86W56-2;Q86W56 Q86W56-3 PARG Poly(ADP-ribose) glycohydrolase 1 0 LENVSQLS(0.007)LDKS(0.534)PT(0.459)EK;LENVSQLS(0.006)LDKS(0.992)PT(0.003)EK ; 192.23 3.25E-06 188845000 7820.7 6529.8 7793 7814.4 7525.3 7735.6 5747.8 8008.8 7967.3 7148.6 TRUE FALSE FALSE 7201.683343 7094.206816 8081.815435 7782.066083 7435.565712 6131.149362 5909.067799 10450.64625 7093.307123 7397.013318 0.9735934 0.95906368 1.092578192 1.052055167 1.005211887 0.828868233 0.798845094 1.412819716 0.958942051 1 12.85272716 -8.2684076 0.004022001 0.000116893 1.984557422 0.01609634 0.158354527 101844.9479 192.9500701 47992.6409 47203.22831 5.39E-09 8.2684076 1.984440529 LEPAS(ph)PPEDTSAEVSR ddPTM_HeLa_Curcumin_4h_R1 2 LEPASPPEDTSAEVSR 16 0 E9PFE2;Q9UHL9-2;Q9UHL9;Q9UHL9-3 E9PFE2 GTF2IRD1 General transcription factor II-I repeat domain-containing protein 1 1 0 LEPAS(0.984)PPEDT(0.004)S(0.001)AEVS(0.011)R;LEPAS(0.952)PPEDT(0.004)S(0.044)AEVSR ; 152.68 0.00033355 37646400 7065.2 6060.4 6473.1 6650.2 7547.9 7400.3 6115.7 3611 6341.5 5660.4 TRUE FALSE FALSE 6505.981965 6584.233971 6712.99878 6622.683234 7457.896222 5865.394361 6287.290082 4711.977277 5645.853316 5857.098479 1.110785825 1.124146025 1.146130427 1.130710583 1.273309003 1.001416381 1.073447903 0.804490021 0.963933479 1 12.51597044 -4.11806633 2.335801605 1.083759132 0.654382226 0.499879909 0.085526235 0.756358638 3.335317592 0.01233514 0.760977723 7.62E-05 4.11806633 -0.429376906 LEPAT(ph)EY(ph)MARVR ddPTM_HeLa_Curcumin_4h_R1 1 LEPATEYMARVR 12 1 H0Y9E3 H0Y9E3 OSMR 2 0 LEPAT(1)EY(1)MARVR 66.267 0.0086761 0 683.89 670.67 766.15 595.73 617.98 1061 698.52 394.85 749.43 820.3 TRUE FALSE FALSE 629.7593849 728.6397264 794.544193 593.2650271 610.6109921 840.9366401 718.1185912 515.2379473 667.219404 848.8053639 0.741936151 0.858429691 0.936073482 0.698941185 0.719376924 0.990729649 0.846034464 0.607015423 0.786068788 1 9.729289963 -9.422213442 1.024950301 1.005892482 0.802381124 0 0.126632443 0.556019689 0.994950785 0.086088709 0.019301194 3.78E-10 9.422213442 -0.203511359 LEPLK(ac)PLK ddPTM_HeLa_Curcumin_4h_R1 1 LEPLKPLK 8 1 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 0 1 LEPLK(1)PLK 96.948 0.015923 13264000 7243.9 5540.1 8021.2 6690.5 7162.3 7363 6586.6 2148.1 6338.5 5471.3 FALSE TRUE FALSE 6670.537671 6018.961558 8318.472728 6662.816484 7076.89425 5835.830802 6771.402269 2803.045801 5643.182408 5661.427268 1.17824311 1.063152677 1.469324313 1.176879287 1.250019459 1.030805577 1.196059218 0.495112923 0.996777339 1 12.46695009 -4.257710358 24.61504654 1.129287985 0.495112618 0.671215025 0.136991923 142.1294908 938137.6574 0.019527193 0.193411994 5.52E-05 4.257710358 -0.634175367 ALNHSVEDIEPDLLT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 5 ALNHSVEDIEPDLLTPR 17 0 I3L2K5;Q8IWR0 I3L2K5 ZC3H7A Zinc finger CCCH domain-containing protein 7A 1 0 ALNHSVEDIEPDLLT(1)PR;ALNHSVEDIEPDLLT(1)PR;ALNHSVEDIEPDLLT(1)PR;ALNHSVEDIEPDLLT(1)PR;ALNHSVEDIEPDLLT(1)PR ;;;; 189.98 2.02E-07 48610300 6478.8 6471.62 6041.58 6443.1 6361.01 7933.9 7642.1 14673.2 7432.1 6706.5 TRUE FALSE FALSE 5965.996144 7030.997996 6265.48627 6416.440159 6285.15911 6288.319707 7856.516758 19146.99113 6616.817224 6939.550376 0.859709321 1.013177744 0.902866314 0.924619004 0.905701201 0.906156648 1.132136282 2.759111195 0.953493651 1 12.76062648 -4.257109238 3.511798749 0.932943809 2.988285075 0.993397943 0.044375092 0.020457087 0.434071643 0.007970704 0.111617837 5.53E-05 4.257109238 2.055341266 up LEPQELS(ph)PLSATVFPK ddPTM_HeLa_Curcumin_4h_R1 2 LEPQELSPLSATVFPK 16 0 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9;Q9H869-7;Q9H869-5;Q9H869-6;Q9H869-4;Q9H869-3;Q9H869-2;Q9H869;Q9H869-8;Q9H869-9 A0A087WUE6 GON4L;YY1AP1 GON-4-like protein;YY1-associated protein 1 1 0 LEPQELS(0.993)PLS(0.007)ATVFPK;LEPQELS(0.881)PLS(0.083)AT(0.036)VFPK ; 242.67 3.42E-30 80137000 12358.8 10516.7 10459.5 10099.7 10479.1 11970.1 7770.9 4899.2 12113.4 10309.6 TRUE FALSE FALSE 11380.58794 11425.71669 10847.13827 10057.91012 10354.14358 9487.366329 7988.93054 6392.943527 10784.59033 10667.85783 1.066810987 1.071041334 1.016805664 0.942823787 0.970592572 0.889341279 0.748878609 0.599271534 1.010942449 1 13.38098288 -4.192800991 0.704843344 1.034155297 0.277788185 0.958990006 0.028868839 0.481880632 0.156145369 0.005960207 0.296046247 6.42E-05 4.192800991 -0.756367112 LEPSTSTDQPVT(ph)PEPTSQATR ddPTM_HeLa_Curcumin_4h_R1 4 LEPSTSTDQPVTPEPTSQATR 21 0 Q14676;Q14676-3;Q14676-2 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 LEPS(0.001)T(0.001)S(0.013)T(0.013)DQPVT(0.957)PEPT(0.012)S(0.004)QATR;LEPSTST(0.003)DQPVT(0.997)PEPTSQATR;LEPSTSTDQPVT(0.982)PEPT(0.018)SQATR;LEPS(0.001)TS(0.001)T(0.162)DQPVT(0.637)PEPT(0.159)S(0.04)QAT(0.001)R ;;; 212.55 3.07E-18 73947000 6338 4680.81 5094.93 5712.72 5393.75 6859.28 5197.69 3552.92 6085.6 4852.49 TRUE FALSE FALSE 5836.340612 5085.398359 5283.752588 5689.082278 5329.433054 5436.588008 5343.523193 4636.188952 5418.024905 5021.113666 1.162359787 1.012802875 1.052306906 1.133031964 1.061404582 1.082745456 1.06421076 0.923338777 1.079048447 1 12.29379167 -4.261629927 4.385221597 1.07513812 0.912530613 0.483504731 0.046125052 0.181100484 8.385172414 0.008590655 0.091144973 5.47E-05 4.261629927 -0.162607507 IMSCS(ph)PDTQCSR ddPTM_HeLa_Curcumin_4h_R1 2 IMSCSPDTQCSR 12 0 Q9C0C9;K7EQ12 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 0 IMS(0.08)CS(0.919)PDT(0.001)QCSR;IMS(0.042)CS(0.893)PDT(0.065)QCSR ; 139.19 0.0012874 52815000 4180.1 3639.1 3470.8 3589.9 3033.6 3843.7 2151.6 1124.55 4037.3 3253.1 TRUE FALSE FALSE 3849.240674 3953.647588 3599.430901 3575.045945 2997.426301 3046.473293 2211.968105 1467.420118 3594.418291 3366.144983 1.143516008 1.174532769 1.069303586 1.062059407 0.890462626 0.905033297 0.657122054 0.435934912 1.067814461 1 11.7168816 -4.38953437 0.818486754 1.079014763 0.13120541 0.932312067 0.05734079 0.447647013 0.243686123 0.011747409 0.367397132 4.08E-05 4.38953437 -0.947809352 down SGGDFKPTS(ph)PSLPASK ddPTM_HeLa_Curcumin_4h_R1 1 SGGDFKPTSPSLPASK 16 1 Q5T5P2;Q5T5P2-7;Q5T5P2-9;Q5T5P2-2;Q5T5P2-10 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 0 SGGDFKPT(0.059)S(0.683)PS(0.2)LPAS(0.058)K 111.7 0.014322 11944000 1680.9 1462.9 1442.9 1596 1651.4 1402.5 1138.2 513.89 1610.4 1346.4 TRUE FALSE FALSE 1547.854991 1589.346557 1496.375143 1589.396175 1631.708134 1111.605691 1170.134829 670.5726953 1433.743149 1393.1873 1.111017156 1.140798913 1.074066024 1.140834528 1.171205145 0.797886753 0.839897714 0.481322716 1.02911012 1 10.44417351 -4.389329573 1.142551756 1.073577478 0.311700662 0.839465615 0.081971783 0.402220252 0.494106189 0.013034634 0.344991782 4.08E-05 4.389329573 -0.761876815 down LEPVS(ph)PPS(ph)PPHTDPELELVPPR ddPTM_HeLa_Curcumin_4h_R1 3 LEPVSPPSPPHTDPELELVPPR 22 0 Q9Y618;C9J0Q5;Q9Y618-4;C9JE98;Q9Y618-5;C9JQE8;H7C1Y3;H0YGK8;C9J330 Q9Y618 NCOR2 Nuclear receptor corepressor 2 2 0 LEPVS(1)PPS(1)PPHTDPELELVPPR;LEPVS(1)PPS(0.999)PPHT(0.001)DPELELVPPR;LEPVS(1)PPS(0.998)PPHT(0.002)DPELELVPPR ;; 136.61 1.98E-05 92242000 12931.6 10857.4 11354.1 12351.7 10803.6 13202.5 10171.8 5207.9 12481.5 11553.5 TRUE FALSE FALSE 11908.05021 11795.86528 11774.89293 12300.59194 10674.77413 10464.15268 10457.19333 6795.764736 11112.31068 11954.98327 0.996074185 0.986690237 0.984935961 1.028909172 0.892914184 0.875296305 0.874714176 0.568446194 0.929512859 1 13.54532449 -3.759220413 0.794546201 0.996130235 3.16E-16 0.88097293 0.0437468 0.909867218 0.239163946 0.005735969 0.965960496 0.000174092 3.759220413 -0.996130235 AKS(ph)PTPESSTIASYVTLR ddPTM_HeLa_Curcumin_4h_R1 1 AKSPTPESSTIASYVTLR 18 1 A0JP02;B4DJX4;Q9HAU0-8;Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;Q9HAU0-5;H0YGJ6 A0JP02 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 0 AKS(0.8)PT(0.2)PESSTIASYVTLR 75.106 0.0043093 307350000 1775.6 1739.3 1501.4 1633 1498.1 1356.4 1054.1 383.77 1471 1252.3 TRUE FALSE FALSE 1635.059386 1889.637342 1557.043205 1626.243079 1480.236136 1075.06735 1083.675209 500.7797063 1309.63498 1295.817332 1.261797744 1.458259043 1.201591587 1.254994079 1.142318519 0.829644213 0.836287016 0.386458565 1.010663269 1 10.33964664 -4.38931507 1.022987131 1.16976892 0.13401291 0.763346964 0.139493217 0.655493083 0.611900824 0.024772922 0.702271613 4.08E-05 4.38931507 -1.03575601 down SES(ph)LIDASEDSQLEAAIR ddPTM_HeLa_Curcumin_4h_R1 2 SESLIDASEDSQLEAAIR 18 0 C9JAT7;O94888 C9JAT7 UBXN7 UBX domain-containing protein 7 1 0 SES(0.999)LIDASEDSQLEAAIR;S(0.001)ES(0.999)LIDASEDSQLEAAIR ; 157.7 4.43E-05 14041400 2067.68 1633.57 1607.42 2119.11 1715.98 2250.57 2764.6 9036 2179.57 1761.91 TRUE FALSE FALSE 1904.020946 1774.768512 1666.992399 2110.341684 1695.518059 1783.776413 2842.167235 11791.0348 1940.476624 1823.136241 1.044365694 0.973470041 0.914354266 1.157533725 0.930000743 0.978410923 1.558943962 6.467445787 1.064361829 1 10.83220666 -4.257075777 3.636249271 1.015243891 7.103536888 0.998197843 0.069161627 0.008484217 0.201883182 0.010433313 0.140382574 5.53E-05 4.257075777 6.088292997 up LEPVYSPPGS(ph)PPPGDPR ddPTM_HeLa_Curcumin_4h_R1 1 LEPVYSPPGSPPPGDPR 17 0 A0A0A6YYC0;E9PJN1;O75676-2;O75676 A0A0A6YYC0 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 0 LEPVYS(0.211)PPGS(0.789)PPPGDPR 199.05 3.31E-08 48554000 1762.6 1548.9 1555.5 1708.7 1700.1 2261.2 2454.7 459.08 1450.6 1807.6 TRUE FALSE FALSE 1623.08835 1682.780014 1613.148198 1701.629852 1679.827418 1792.201631 2523.572276 599.0513787 1291.472809 1870.413965 0.867769585 0.899683196 0.862455172 0.909761092 0.898104617 0.958184479 1.349205215 0.32027743 0.690474319 1 10.86914189 -9.404671139 1.10582505 1.000556174 0.899642697 0 0.252296289 1.891044477 4.100209157 0.148229208 0.036846244 3.94E-10 9.404671139 -0.100913477 T(ph)ASEGDGGAAAGAAAAGAR ddPTM_HeLa_Curcumin_4h_R1 3 TASEGDGGAAAGAAAAGAR 19 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 T(0.919)AS(0.081)EGDGGAAAGAAAAGAR;T(0.935)AS(0.065)EGDGGAAAGAAAAGAR;T(0.701)AS(0.299)EGDGGAAAGAAAAGAR ;; 270.78 4.00E-55 518380300 3735.5 4448.6 4486.3 4264.1 4809.3 4518.3 2966.07 1245.79 4026.1 4009.5 TRUE FALSE FALSE 3439.831233 4833.117161 4652.566225 4246.456284 4751.952239 3581.153648 3049.289941 1625.625636 3584.446903 4148.829827 0.829108779 1.164935021 1.1214165 1.023531083 1.145371692 0.863171978 0.734975901 0.391827504 0.863965757 1 12.01848877 -4.388969167 1.735067585 0.972606101 0.284202574 0.736139563 0.114391611 0.333085538 1.193716983 0.019078121 0.346451005 4.08E-05 4.388969167 -0.688403527 down SIDKDEEFAGS(ph)SPQSSK ddPTM_HeLa_Curcumin_4h_R1 1 SIDKDEEFAGSSPQSSK 17 1 A0A590UJ38;H3BQ24;A0A590UJL5;Q9Y2M0-2;Q9Y2M0 A0A590UJ38 FAN1 Fanconi-associated nuclease 1 1 0 SIDKDEEFAGS(0.492)S(0.492)PQS(0.013)S(0.003)K 63.488 0.012527 13660000 2170.4 2120.8 1983.1 2140.7 2405.7 2548.6 1545.3 654.77 2342.2 2349.4 TRUE FALSE FALSE 1998.61055 2304.112502 2056.595431 2131.842351 2377.013599 2019.991631 1588.656959 854.4063588 2085.26652 2431.041475 0.822121124 0.947788232 0.845972992 0.876925537 0.977775831 0.830916153 0.653488217 0.351456924 0.85776674 1 11.24735879 -4.388386843 1.553903358 0.912397297 0.220549197 0.902809089 0.056307644 0.219705412 0.590371279 0.010441643 0.213572684 4.09E-05 4.388386843 -0.6918481 down LEQLESGEEELVLAEYES(ph)DEEKK ddPTM_HeLa_Curcumin_4h_R1 3 LEQLESGEEELVLAEYESDEEKK 23 1 F5GXJ8;F6WZM0;F5H235;C9K0E8;B4DMS8;Q96FC9-5;Q96FC9-4;Q96FC9-3;Q96FC9-2;Q96FC9;A8MPP1 F5GXJ8 DDX11;DDX11L8 Probable ATP-dependent RNA helicase DDX11;Putative ATP-dependent RNA helicase DDX11-like protein 8 1 0 LEQLESGEEELVLAEY(0.478)ES(0.522)DEEKK;LEQLESGEEELVLAEY(0.053)ES(0.947)DEEKK;LEQLESGEEELVLAEY(0.213)ES(0.787)DEEKK ;; 90.899 8.27E-05 5154200 2192.79 1717.59 2143.62 1850.24 2188.96 1836.9 1423.95 911.53 1532.56 1727.06 TRUE FALSE FALSE 2019.228358 1866.050826 2223.064443 1842.584197 2162.858082 1455.906234 1463.902205 1189.451301 1364.442002 1787.075206 1.129906761 1.044192667 1.243968041 1.031061362 1.210278154 0.814686606 0.819160939 0.665585475 0.763505642 1 10.80338463 -5.130977827 5.174149705 1.081348062 0.759433127 0.514859151 0.13042394 0.087133249 3.29522327 0.012358676 0.032578703 7.40E-06 5.130977827 -0.321914934 LEQLESGEEELVLAEYES(ph)DEEKKVASR ddPTM_HeLa_Curcumin_4h_R1 1 LEQLESGEEELVLAEYESDEEKKVASR 27 2 F5GXJ8;F6WZM0;F5H235;C9K0E8;B4DMS8;Q96FC9-5;Q96FC9-4;Q96FC9-3;Q96FC9-2;Q96FC9 F5GXJ8 DDX11 Probable ATP-dependent RNA helicase DDX11 1 0 LEQLESGEEELVLAEY(0.45)ES(0.539)DEEKKVAS(0.011)R 78.451 1.94E-05 16033000 891.16 653.97 737.98 800.94 944.82 827.28 451.92 552.49 797.24 754.24 TRUE FALSE FALSE 820.6237457 710.4962528 765.330188 797.6259225 933.5536386 655.6928026 464.5996589 720.9416576 709.7847666 780.4497839 1.051475396 0.910367672 0.980627074 1.022008 1.19617387 0.840147331 0.595297313 0.923751499 0.909456036 1 9.608161998 -5.012373566 24.32661858 1.022285397 0.749073859 0.489433014 0.106177651 191.7333533 376954.315 0.012770945 0.034602635 9.72E-06 5.012373566 -0.273211539 LEQLESGEEELVLAEYESDEEKKVAS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 LEQLESGEEELVLAEYESDEEKKVASR 27 2 F5GXJ8;F6WZM0;F5H235;C9K0E8;B4DMS8;Q96FC9-5;Q96FC9-4;Q96FC9-3;Q96FC9-2;Q96FC9 F5GXJ8 DDX11 Probable ATP-dependent RNA helicase DDX11 1 0 LEQLESGEEELVLAEY(0.081)ES(0.419)DEEKKVAS(0.5)R 53.865 0.0018725 5435100 469.41 453.77 431.62 462.63 507.86 349.69 388.27 298.64 544.07 515.31 TRUE FALSE FALSE 432.2557032 492.9918568 447.6162169 460.7157596 501.8041012 277.1603522 399.1638112 389.6939612 484.3868822 533.2169841 0.810656292 0.924561429 0.83946354 0.864030542 0.941087993 0.519789055 0.748595456 0.730835613 0.908423581 1 9.058578924 -2.371003981 0.06582032 1.258627076 1.23E-12 0.403880439 0.100854238 138.9398971 0.89701928 3.992053905 17.60326113 0.004255945 2.371003981 -1.258627076 LEQYTSAIEGTK ddPTM_HeLa_Curcumin_4h_R1 1 LEQYTSAIEGTK 12 0 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1;C9J813 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 0 0 162.93 6.43E-06 2246600 1230.3 968.97 1195.2 1285.1 1165.9 1369.6 1076.9 1225.1 1493.4 1225.4 FALSE FALSE TRUE 1132.920457 1052.723449 1239.495163 1279.782597 1151.997404 1085.529521 1107.114916 1598.62735 1329.577756 1267.982559 0.893482682 0.83023496 0.977533291 1.009306152 0.9085278 0.856107613 0.873131028 1.260764463 1.048577322 1 10.30831919 -4.254902741 24.95270483 0.933815343 1.260764615 0.668817783 0.069193212 330.5454753 1261776.4 0.009396797 0.119446759 5.56E-05 4.254902741 0.326949272 LERENAEVDGDDDAEEMEAK ddPTM_HeLa_Curcumin_4h_R1 2 LERENAEVDGDDDAEEMEAK 20 1 P05198 P05198 EIF2S1 Eukaryotic translation initiation factor 2 subunit 1 0 0 ; ; 246.48 3.78E-34 29943000 6834.6 5547.5 6345 5968.4 6097.2 7579.5 5689.7 5908.9 6739.8 5594.9 FALSE FALSE TRUE 6293.634198 6027.001181 6580.151282 5943.704342 6024.494872 6007.426261 5849.337669 7710.496409 6000.460802 5789.322359 1.087110686 1.041054688 1.136601294 1.026666676 1.040621769 1.037673477 1.010366552 1.331847828 1.036470321 1 12.49917877 -4.257154443 24.99120027 1.045492726 1.331847942 0.840978021 0.037251381 141.2969852 824060.369 0.005913192 0.062213699 5.53E-05 4.257154443 0.286355216 LERENAEVDGDDDAEEMEAKAED ddPTM_HeLa_Curcumin_4h_R1 4 LERENAEVDGDDDAEEMEAKAED 23 2 P05198 P05198 EIF2S1 Eukaryotic translation initiation factor 2 subunit 1 0 0 ;;; ;;; 218.38 9.27E-23 82002300 9631.4 6972.97 6469.28 8171.2 4978.18 10375.4 7429.93 6762.3 13285.2 9723.1 FALSE FALSE TRUE 8869.064527 7575.682456 6709.037208 8137.389739 4918.818455 8223.425085 7638.393839 8824.09414 11827.8468 10060.977 0.88153114 0.752976819 0.666837545 0.808807111 0.488900676 0.817358501 0.759209949 0.877061357 1.175616125 1 13.29648279 -7.586766708 1.185509072 0.966404095 0.729691511 0.520971985 0.121314399 0.245126691 0.701267316 0.022284637 0.022753409 2.59E-08 7.586766708 -0.236712585 LES(ph)SEGEIIQTVDR ddPTM_HeLa_Curcumin_4h_R1 1 LESSEGEIIQTVDR 14 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 0 LES(0.642)S(0.358)EGEIIQTVDR 254.45 1.34E-38 9447500 1649.9 1439.2 1707.8 1425 1576.6 1704.7 1236.4 1271.7 1563.7 1328.9 TRUE FALSE FALSE 1519.308674 1563.598035 1771.09257 1419.103728 1557.800075 1351.126004 1271.090056 1659.435476 1392.166022 1375.079176 1.104888141 1.13709673 1.287993158 1.032016012 1.132880275 0.982580514 0.924375904 1.206792674 1.012426082 1 10.42529898 -3.912039026 14.60551326 1.065846851 3.922187245 0.15248256 0.097838977 851492.895 2341269.874 0.58375998 76470120.6 0.000122451 3.912039026 2.856340394 LESEST(ph)SPSLEMK ddPTM_HeLa_Curcumin_4h_R1 1 LESESTSPSLEMK 13 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 LES(0.001)ES(0.098)T(0.815)S(0.077)PS(0.008)LEMK 158.42 4.88E-07 0 3939.8 3229.2 3158.5 2965.8 3202.2 4818.5 2923.1 3376.2 3902.8 3048.2 TRUE FALSE FALSE 3627.960673 3508.317659 3275.556788 2953.528305 3164.015856 3819.088784 3005.114319 4405.587838 3474.672604 3154.124723 1.150227398 1.112295159 1.038499449 0.936401875 1.003135936 1.210823642 0.952756971 1.396770332 1.101628157 1 11.62302399 -4.249338315 24.56181249 1.062783139 1.396770595 0.598770012 0.083480578 859.4640172 1744434.504 0.012185813 0.271080542 5.63E-05 4.249338315 0.333987455 LESGGGGEGGEGT(ph)EEEDGAER ddPTM_HeLa_Curcumin_4h_R1 3 LESGGGGEGGEGTEEEDGAER 21 0 Q96LA8 Q96LA8 PRMT6 Protein arginine N-methyltransferase 6 1 0 LESGGGGEGGEGT(1)EEEDGAER;LESGGGGEGGEGT(1)EEEDGAER;LESGGGGEGGEGT(1)EEEDGAER ;; 166.21 1.60E-15 21923400 1668.94 1474.49 1609.58 1590.37 1850.84 2115.61 1579.36 1037.38 1768.41 1674.01 TRUE FALSE FALSE 1536.841638 1601.938345 1669.232451 1583.78947 1828.769942 1676.808638 1623.672591 1353.672386 1574.419847 1732.181723 0.887228873 0.924809634 0.963658968 0.914332168 1.05576102 0.968032751 0.937356958 0.781484049 0.908923023 1 10.75837458 -7.505437804 0.007959357 1.885148727 2.08E-06 0.044570268 0.067564708 3604.749568 24.49245501 2906.652681 2892.347271 3.12E-08 7.505437804 -1.885146643 LESLSETPGPS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 4 LESLSETPGPSSPR 14 0 A0A2R8YFR7;Q12774;A0A2R8YF49;H0Y895;C9J591;Q12774-2 A0A2R8YFR7 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 0 LESLSETPGPS(0.5)S(0.5)PR;LESLSETPGPS(0.5)S(0.5)PR;LESLSETPGPS(0.96)S(0.04)PR;LESLSET(0.024)PGPS(0.965)S(0.011)PR ;;; 241.76 1.18E-28 158637800 14232.6 12334.6 13570.9 12937.8 14066.2 14242.2 11198.7 5638.7 13582.7 11430.1 TRUE FALSE FALSE 13106.07469 13400.74786 14073.84949 12884.26681 13898.46975 11288.20718 11512.90538 7357.913673 12092.71179 11827.29512 1.10812105 1.133035721 1.189946589 1.089367153 1.1751182 0.954420014 0.973418289 0.622112968 1.022441029 1 13.52983255 -3.910522847 1.280576514 1.077125726 0.032101958 0.809882009 0.067973268 1.099033706 0.84357357 0.01132671 1.867723624 0.000122879 3.910522847 -1.045023768 LESLYS(ph)DEEDESAVGADK ddPTM_HeLa_Curcumin_4h_R1 2 LESLYSDEEDESAVGADK 18 0 Q9UP95-3;Q9UP95-5;Q9UP95-2;Q9UP95-6;Q9UP95;I3L4N6;Q9UP95-7 Q9UP95-3 SLC12A4 Solute carrier family 12 member 4 1 0 LESLYS(1)DEEDESAVGADK;LESLYS(1)DEEDESAVGADK ; 227.41 1.64E-23 25771000 6788.4 6090.5 7939.3 7649.5 8177 8015 4899.9 2740.62 7252.5 6865.5 TRUE FALSE FALSE 6251.090977 6616.935681 8233.537442 7617.848396 8079.494616 6352.598652 5037.378007 3576.222422 6456.918895 7104.075614 0.879930242 0.931428104 1.158987867 1.072320849 1.137304141 0.894218896 0.709082825 0.50340433 0.908903458 1 12.79443122 -4.60437787 2.201485526 0.979520068 0.506926038 0.755942167 0.093015056 0.159848782 1.344239998 0.015298796 0.111235718 2.49E-05 4.60437787 -0.47259403 LESS(ph)EGEIIQTVDR ddPTM_HeLa_Curcumin_4h_R1 2 LESSEGEIIQTVDR 14 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 0 LES(0.104)S(0.896)EGEIIQTVDR;LES(0.039)S(0.961)EGEIIQTVDR ; 247.38 3.40E-29 18595900 3290.5 3221.3 3384.1 2955.6 4239.3 3934.5 3219.37 3118.5 3406.9 3133.3 TRUE FALSE FALSE 3030.053453 3499.734818 3509.517723 2943.37051 4188.749116 3118.440349 3309.696858 4069.316294 3033.171594 3242.181942 0.934572306 1.079438132 1.082455515 0.907836316 1.29195375 0.961833853 1.020823913 1.255116575 0.935534047 1 11.66274934 -6.517345051 0.831904767 0.970895654 1.103970802 0.203180665 0.112983486 0.704558127 0.974267668 0.021695988 0.041544002 3.04E-07 6.517345051 0.133075148 LESSDLT(ph)PPHS(ph)PPPSSR ddPTM_HeLa_Curcumin_4h_R1 1 LESSDLTPPHSPPPSSR 17 0 Q9H7P9-3;Q9H7P9;H7BXC7 Q9H7P9-3 PLEKHG2 Pleckstrin homology domain-containing family G member 2 2 0 LES(0.201)S(0.38)DLT(0.422)PPHS(0.985)PPPS(0.008)S(0.005)R 121.45 0.00076243 0 1998.9 1754.5 1808.2 1845.3 2080.4 2465.1 1784.9 1118 2085.1 1905.6 TRUE FALSE FALSE 1840.684956 1906.151162 1875.213483 1837.664638 2055.592589 1953.810473 1834.97949 1458.873053 1856.369747 1971.819458 0.933495685 0.966696598 0.951006683 0.931963943 1.042485193 0.990866818 0.930602182 0.739861374 0.941450161 1 10.94531175 -4.273867728 3.173208226 0.970318389 0.709173021 0.81580557 0.032599642 0.110600159 1.741471129 0.004990928 0.070233729 5.32E-05 4.273867728 -0.261145368 LESSNGK(ac)MASR ddPTM_HeLa_Curcumin_4h_R1 1 LESSNGKMASR 11 1 Q9NQ29;Q9NQ29-3;B8ZZ08 Q9NQ29 LUC7L Putative RNA-binding protein Luc7-like 1 0 1 LESSNGK(1)MASR 127.51 0.0011017 2931200 590.33 501.55 441.15 436.96 472 682.27 537.86 477.6 453.82 428.73 FALSE TRUE FALSE 543.6047576 544.9017471 457.4994071 435.1519753 466.3717083 540.7595112 552.950904 623.2180414 404.0370814 443.6283356 1.225360767 1.228284362 1.031267325 0.980893104 1.051266727 1.218947186 1.246428282 1.404820187 0.910755804 1 8.793207707 -4.588527806 1.531941672 1.100770981 1.420132645 0.514428487 0.103096486 0.453844787 1.503200815 0.015913877 0.180751756 2.58E-05 4.588527806 0.319361664 LEVPAERS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 LEVPAERSPR 10 1 Q9UJF2-2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 0 LEVPAERS(1)PR;LEVPAERS(1)PR ; 133.15 0.0010817 56293000 6163.1 4893.7 5742.2 5963.9 5393.1 6170.1 3852.6 2555.9 6789.4 5002.8 TRUE FALSE FALSE 5675.284132 5316.689622 5955.010983 5939.222962 5328.790805 4890.351709 3960.693587 3335.182144 6044.619806 5176.646928 1.09632436 1.027052781 1.150360661 1.147310807 1.02939043 0.944694853 0.765107925 0.644274603 1.167670867 1 12.33780221 -4.739994807 1.674610531 1.060506572 0.633047883 0.872776907 0.058390783 0.120517085 0.568717832 0.0085246 0.061762364 1.82E-05 4.739994807 -0.427458689 LEYGDNAEK ddPTM_HeLa_Curcumin_4h_R1 1 LEYGDNAEK 9 0 Q9Y224;H0YJB9;G3V4C6 Q9Y224 C14orf166 UPF0568 protein C14orf166 0 0 112.75 0.0027246 3067300 1668.5 1762.6 1416.9 1512.2 1403.3 1627 1381.8 1381.7 1563.6 1402.6 FALSE FALSE TRUE 1536.436464 1914.95129 1469.41156 1505.942917 1386.566564 1289.54186 1420.569589 1802.973969 1392.076992 1451.340246 1.058632853 1.319436497 1.012451467 1.03762224 0.955369748 0.88851795 0.978798454 1.242282073 0.959166533 1 10.50317006 -6.566860717 24.99983086 1.055847233 1.009024664 0.039150403 0.124697359 451.9595819 256897.0028 0.01970436 0.027866196 2.71E-07 6.566860717 -0.046822569 LFCITS(ph)S(ph)MSTIPERT(ph)PGPK ddPTM_HeLa_Curcumin_4h_R1 1 LFCITSSMSTIPERTPGPK 19 1 H3BQL0 H3BQL0 KLHDC4 3 0 LFCIT(0.192)S(0.79)S(0.614)MS(0.203)T(0.203)IPERT(0.998)PGPK 51.089 0.0088448 0 3053.4 1994 2559.3 2248.2 2375.9 2656.1 1974.6 1424.5 2615.4 2005.1 TRUE FALSE FALSE 2811.720168 2166.352475 2654.149909 2238.897544 2347.568944 2105.19492 2030.001962 1858.823492 2328.497163 2074.777076 1.355191457 1.044137464 1.279245824 1.0791027 1.131480086 1.014660777 0.978419313 0.895914802 1.122287879 1 11.01874062 -4.976437836 1.047267735 1.166909635 0.888437211 0.428089089 0.100048201 0.717472354 1.166469025 0.021589929 0.167522669 1.06E-05 4.976437836 -0.278472424 LFCVGFTK ddPTM_HeLa_Curcumin_4h_R1 2 LFCVGFTK 8 0 P61247;H0Y9Y4;D6RAT0;D6R9B6;D6RG13;D6RB09;E9PFI5;H0Y8L7;D6RAS7 P61247 RPS3A 40S ribosomal protein S3a 0 0 ; ; 123.69 0.002326 6993700 8617.3 6270.2 7446.9 6972.3 7565.3 6324.5 5897 5863.5 7060.5 7177.1 FALSE FALSE TRUE 7935.231612 6812.168149 7722.888665 6943.45047 7475.088739 5012.727408 6062.453949 7651.254158 6285.980815 7426.503691 1.068501672 0.917277959 1.039909086 0.9349555 1.006542116 0.674978108 0.816326794 1.030263294 0.846425327 1 12.85846745 -5.417227097 11.71301824 1.016167986 0.838108483 0.177400618 0.106189138 0.43605727 46.35184188 0.012813125 0.028657268 3.83E-06 5.417227097 -0.178059503 LFDDEAS(ph)VDEPRR ddPTM_HeLa_Curcumin_4h_R1 2 LFDDEASVDEPRR 13 1 A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;Q8NI35-5 A0A2R8Y549 INADL InaD-like protein 1 0 LFDDEAS(1)VDEPRR;LFDDEAS(1)VDEPRR ; 104.09 0.0024906 5052000 2365.5 2361.8 2647.2 2172.8 2422 3049 2535.1 2245.8 2359.5 2632 TRUE FALSE FALSE 2178.268179 2565.943468 2745.307561 2163.809529 2393.119232 2416.603031 2606.228083 2930.534082 2100.668753 2723.461804 0.799815946 0.942162458 1.008021319 0.794507023 0.8787049 0.887327675 0.956954153 1.076032745 0.771323009 1 11.41122592 -4.335507659 2.577453953 0.90282936 1.097631469 0.337952262 0.079179082 0.423399777 3.969051863 0.011986122 0.164735498 4.62E-05 4.335507659 0.19480211 LFDEEEDS(ph)SEKLFDDSDER ddPTM_HeLa_Curcumin_4h_R1 4 LFDEEEDSSEKLFDDSDER 19 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 LFDEEEDS(0.541)S(0.458)EKLFDDSDER;LFDEEEDS(0.946)S(0.054)EKLFDDSDER;LFDEEEDS(0.5)S(0.5)EKLFDDSDER;LFDEEEDS(0.843)S(0.157)EKLFDDSDER ;;; 109.67 0.00022145 35997800 7382 7490.4 8051 6489.6 9801.4 8307 6356.7 7292.9 6929.9 6759.3 TRUE FALSE FALSE 6797.706911 8137.836799 8349.377142 6462.747755 9684.524707 6584.034561 6535.051894 9516.471638 6169.707308 6994.185172 0.971908342 1.163514634 1.193759807 0.924017251 1.384653747 0.941358343 0.934355001 1.360626206 0.882119526 1 12.77194028 -7.269801912 24.06894226 0.98673449 1.118653813 0.196977061 0.158613751 522.1246506 1502770.405 0.024402828 0.028170196 5.37E-08 7.269801912 0.131919323 LFDQAFGLPR ddPTM_HeLa_Curcumin_4h_R1 1 LFDQAFGLPR 10 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 0 0 96.143 0.014807 540230 125.09 0 236.96 210.44 39.895 1677.3 522.2 362.77 137.08 223.96 FALSE FALSE TRUE 115.1889945 0 245.7419461 209.569255 39.41927818 1329.409073 536.8515266 473.376903 122.042667 231.7425933 0.497055776 0 1.060409062 0.904319107 0.170099409 5.736576319 2.316585479 2.042684067 0.526630281 1 7.85637942 -5.296074523 24.99989574 0.698388631 3.26041381 0.625107757 0.980121029 281.4006961 203116.6037 0.131336327 0.293689073 5.06E-06 5.296074523 2.562025178 HSS(ph)ETFSSTPSATR ddPTM_HeLa_Curcumin_4h_R1 2 HSSETFSSTPSATR 14 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 0 HS(0.031)S(0.967)ET(0.001)FSSTPSATR;HS(0.033)S(0.967)ETFSSTPSATR ; 160.48 0.00029112 42797000 4952.6 4119.5 3111.34 3509.98 4555.62 5570.2 2777.26 635.29 4887.7 3663.1 TRUE FALSE FALSE 4560.596484 4475.571224 3226.648997 3495.456633 4501.297207 4414.877731 2855.182441 828.9869965 4351.531538 3790.392452 1.20319902 1.180767237 0.851270426 0.92218858 1.187554393 1.164754781 0.75326829 0.218707431 1.148042477 1 11.88813152 -4.387214937 2.507334795 1.083962548 0.143307322 0.835204029 0.117933074 0.123610335 1.14834052 0.018496864 0.216904364 4.10E-05 4.387214937 -0.940655226 down LFEDDDS(ph)NEK ddPTM_HeLa_Curcumin_4h_R1 1 LFEDDDSNEK 10 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 LFEDDDS(1)NEK 106.79 0.0089907 3350000 1598 1890.3 1758.2 1337.9 2051.1 1519.4 1821.7 1324.2 1525.8 1913.5 TRUE FALSE FALSE 1471.516614 2053.689109 1823.360439 1332.364124 2026.641972 1204.259313 1872.811999 1727.942484 1358.423557 1979.993983 0.743192468 1.037219874 0.920891909 0.672913219 1.023559662 0.608213623 0.945867521 0.872700877 0.686074589 1 10.95128033 LFEDDDS(ph)NEKLFDEEEDSSEK ddPTM_HeLa_Curcumin_4h_R1 2 LFEDDDSNEKLFDEEEDSSEK 21 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 LFEDDDS(1)NEKLFDEEEDSSEK;LFEDDDS(0.988)NEKLFDEEEDS(0.009)S(0.003)EK ; 77.357 0.00067034 19396000 3041.59 2766.5 2761.21 2424.15 3203.3 2809.38 2647.01 2230.74 2235.14 2455.35 TRUE FALSE FALSE 2800.844942 3005.623933 2863.542872 2414.11951 3165.10274 2226.68292 2721.277977 2910.882357 1989.950734 2540.67323 1.102402666 1.183002953 1.127080349 0.950188903 1.245773247 0.876414524 1.07108539 1.145713003 0.783237573 1 11.31099512 -9.258332473 1.089821616 1.001960681 1.085575055 0.188963268 0.123495015 0.949787837 2.089670815 0.057281202 0.017168735 5.52E-10 9.258332473 0.083614374 LFEHYYQELK ddPTM_HeLa_Curcumin_4h_R1 1 LFEHYYQELK 10 0 Q08J23-2;Q08J23;A0A140T9Y7 Q08J23-2 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 0 0 157.78 0.00050088 14154000 7084.9 4734.3 5488.4 5272.5 5929.1 9910.6 7037.9 5226.8 6356.2 6250.4 FALSE FALSE TRUE 6524.122689 5143.511796 5691.804932 5250.683792 5858.399355 7855.029845 7235.364532 6820.427259 5658.940762 6467.600935 1.008739215 0.795273525 0.880048876 0.81184412 0.905807179 1.21451987 1.118709179 1.05455289 0.874967522 1 12.65901495 -5.268492921 24.93862202 0.958142182 1.128205501 0.518408931 0.089978926 424.4762559 1500786.961 0.014660557 0.033432616 5.39E-06 5.268492921 0.170063319 LFGAGGGK(ac)AGK ddPTM_HeLa_Curcumin_4h_R1 2 LFGAGGGKAGK 11 1 Q9H444 Q9H444 CHMP4B Charged multivesicular body protein 4b 0 1 ; LFGAGGGK(1)AGK;LFGAGGGK(1)AGK 167.33 9.84E-09 18969100 7903 6807.6 7226 6471.5 6333.6 9320.4 7246.6 8449.9 8402.3 7105.6 FALSE TRUE FALSE 7277.469211 7396.01861 7493.801917 6444.722648 6258.075957 7387.243977 7449.920093 11026.23561 7480.588712 7352.519071 0.989792633 1.005916277 1.01921557 0.876532599 0.851147191 1.004722858 1.013247299 1.499654133 1.017418471 1 12.84402291 -4.257450152 4.233901486 0.979995762 1.542116948 0.885708591 0.056605948 0.055147606 2.230991946 0.008199681 0.093806323 5.53E-05 4.257450152 0.562121186 LFIGGLNTETNEK ddPTM_HeLa_Curcumin_4h_R1 2 LFIGGLNTETNEK 13 0 P38159;P38159-2;Q96E39;H0Y6E7;H3BT71;A0A1B0GUK8;H3BR27;P38159-3;H3BNC1 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 0 0 ; ; 270.61 1.09E-77 5638000 2053.27 2227.32 2450.89 2122.2 2005.72 2749.7 2271.1 2054.05 2146.3 2492 FALSE FALSE TRUE 1890.751513 2419.839616 2541.722139 2113.418899 1981.803099 2179.381224 2334.820954 2680.320389 1910.85626 2578.596815 0.733248216 0.938432718 0.985699713 0.819600368 0.768558732 0.845181074 0.905461816 1.039449197 0.741044994 1 11.3323705 -9.713001739 1.621272356 0.999855298 0.85428216 0 0.121709144 0.478101186 2.271794212 0.07313507 0.016121194 1.94E-10 9.713001739 -0.145573138 LFIGGLSFETTDDSLREHFEK ddPTM_HeLa_Curcumin_4h_R1 2 LFIGGLSFETTDDSLREHFEK 21 1 P51991;P51991-2 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 0 ; ; 130.01 1.04E-05 17358900 4490.4 3371.95 3257.7 3831.6 3659.24 6196.5 5199.7 4407.09 4905.9 4379.1 FALSE FALSE TRUE 4134.980102 3663.406333 3378.433228 3815.745854 3615.605953 4911.276051 5345.589588 5750.791453 4367.735044 4531.273399 0.91254262 0.808471705 0.745581414 0.842091288 0.797922711 1.083862221 1.179710231 1.269133629 0.963908963 1 12.14570082 -4.947911546 2.897826165 0.91182574 1.22958098 0.733419851 0.085176499 0.134685146 2.268996894 0.014955465 0.052967022 1.13E-05 4.947911546 0.31775524 LFPADT(ph)SPSTATK ddPTM_HeLa_Curcumin_4h_R1 2 LFPADTSPSTATK 13 0 Q6NZY4;Q6NZY4-2 Q6NZY4 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 0 LFPADT(0.747)S(0.246)PS(0.004)T(0.003)ATK;LFPADT(0.472)S(0.472)PS(0.05)T(0.006)AT(0.001)K ; 199.8 2.10E-06 58261000 11087.9 8613.9 8935.4 9715.3 8563.3 10718.3 8658.5 7774.9 10606.1 8004.7 TRUE FALSE FALSE 10210.28102 9358.447133 9266.553784 9675.100663 8461.18824 8495.20376 8901.434207 10145.43122 9442.637365 8282.862729 1.232699533 1.129856601 1.118762207 1.168086564 1.021529454 1.025636189 1.07468088 1.224870139 1.14002099 1 13.01591376 -4.252067426 23.40661353 1.104468639 1.224870295 0.223358194 0.068918576 854.9244074 2135073.221 0.012936312 0.206654505 5.60E-05 4.252067426 0.120401656 LFPADTS(ph)PSTATK ddPTM_HeLa_Curcumin_4h_R1 2 LFPADTSPSTATK 13 0 Q6NZY4;Q6NZY4-2 Q6NZY4 ZCCHC8 Zinc finger CCHC domain-containing protein 8 1 0 LFPADT(0.254)S(0.59)PS(0.058)T(0.094)AT(0.004)K;LFPADT(0.187)S(0.812)PS(0.001)TATK ; 169.17 0.00019169 181052000 5237 3906 4243.6 4876.7 4749 5580 4505.8 3703 5235.9 4201.7 TRUE FALSE FALSE 4822.485924 4243.617235 4400.871549 4856.521508 4692.371277 4422.6451 4632.220621 4832.027653 4661.53487 4347.708762 1.109201694 0.976058303 1.012227771 1.117030089 1.079274518 1.017235823 1.065439493 1.111396351 1.072181952 1 12.08603959 -6.275653173 24.88745444 1.043330616 1.074059929 0.185366213 0.043718211 1703.423901 2982584.959 0.008244489 0.012642051 5.30E-07 6.275653173 0.030729313 LFPDT(ph)PLALDANK ddPTM_HeLa_Curcumin_4h_R1 1 LFPDTPLALDANK 13 0 Q12906;Q12906-7;Q12906-5;Q12906-4;Q12906-2;Q12906-6;Q12906-3 Q12906 ILF3 Interleukin enhancer-binding factor 3 1 0 LFPDT(1)PLALDANK 190.41 2.34E-05 217400000 4156.8 3106 3548.6 4070.9 4469.3 6116.5 6478.8 4447.9 3576.6 3105.5 TRUE FALSE FALSE 3827.784894 3374.4688 3680.114238 4054.055694 4416.006516 4847.868953 6660.577691 5804.044234 3184.255928 3213.415894 1.19118876 1.050118911 1.145234342 1.261603175 1.374240578 1.508634149 2.072740632 1.806191426 0.990925555 1 11.649892 -5.176539876 0.999025852 1.091118499 2.013008773 0.892774488 0.112080906 0.154387691 0.246182902 0.017806948 0.107607163 6.66E-06 5.176539876 0.921890274 LFPDT(ph)PLALDANKK ddPTM_HeLa_Curcumin_4h_R1 1 LFPDTPLALDANKK 14 1 Q12906;Q12906-7;Q12906-5;Q12906-4;Q12906-2;Q12906-6;Q12906-3 Q12906 ILF3 Interleukin enhancer-binding factor 3 1 0 LFPDT(1)PLALDANKK 94.454 0.0040479 150540000 4130.7 3212.4 4006.2 3462.6 3953.7 5786.4 6049.4 4612.2 4021.2 2898.3 TRUE FALSE FALSE 3803.750736 3490.065542 4154.673296 3448.272679 3906.55471 4586.235414 6219.129883 6018.438548 3580.084421 2999.015709 1.268333048 1.163736999 1.385345626 1.149801473 1.302612286 1.529246879 2.073723677 2.006804609 1.19375314 1 11.55027336 -4.981854351 1.608015638 1.155551953 2.09975807 0.900830293 0.108463131 0.103410138 0.484225014 0.019764776 0.098679092 1.04E-05 4.981854351 0.944206116 LFPEFDDS(ph)DYDEVPEEGPGAPAR ddPTM_HeLa_Curcumin_4h_R1 4 LFPEFDDSDYDEVPEEGPGAPAR 23 0 Q96P48-3;Q96P48 Q96P48-3 ARAP1 "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1" 1 0 LFPEFDDS(0.992)DY(0.008)DEVPEEGPGAPAR;LFPEFDDS(0.978)DY(0.022)DEVPEEGPGAPAR;LFPEFDDS(1)DYDEVPEEGPGAPAR;LFPEFDDS(1)DYDEVPEEGPGAPAR ;;; 132.93 2.26E-06 26880600 6392.1 5086.59 5480.08 5802.88 5732.8 7108.8 4912.82 3996.55 6496.62 5275.21 TRUE FALSE FALSE 5886.15854 5526.252174 5683.176586 5778.86922 5664.440104 5634.354747 5050.660507 5215.079697 5783.95704 5458.523155 1.07834269 1.012407938 1.041156449 1.058687315 1.037723931 1.032212301 0.925279671 0.955401223 1.059619402 1 12.41429496 -4.769394693 23.32139817 1.0376198 0.940340435 0.755405969 0.022654973 31.81028563 93256.82345 0.004179867 0.012908532 1.70E-05 4.769394693 -0.097279366 LFPGS(ph)PAIYK ddPTM_HeLa_Curcumin_4h_R1 2 LFPGSPAIYK 10 0 P49792;J3KNE0;J3KQ37;A6NKT7;Q99666;O14715;F8VYC4;P0DJD0;P0DJD1;A0A1W2PNU4;A0A286YES2;Q7Z3J3;F8W705;Q99666-2;H0YBN8;C9JF75;C9J6W1;C9J1W9;Q7Z3J3-2 P49792 RANBP2;RGPD3;RGPD8;RGPD5;RGPD1;RGPD2;RGPD4;RGPD6 E3 SUMO-protein ligase RanBP2;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4 1 0 LFPGS(1)PAIYK;LFPGS(0.999)PAIY(0.001)K ; 121.68 0.0042757 83600000 7054.4 5755.4 5966.5 6096.8 6832.8 11662.6 11068.8 4000.6 6249.2 5068.8 TRUE FALSE FALSE 6496.036796 6252.87113 6187.623739 6071.573057 6751.323323 9243.645295 11379.36074 5220.364524 5563.678395 5244.940423 1.238533953 1.192172003 1.17973194 1.157605724 1.287206866 1.762392811 2.169588178 0.995314361 1.060770561 1 12.35671067 -5.408758199 3.611290282 1.132288972 1.692771749 0.395307717 0.276046895 0.158226078 3.734322086 0.037369236 0.088072817 3.90E-06 5.408758199 0.560482777 LFPIGY(ph)QCS(ph)RVYWSTTDARKR ddPTM_HeLa_Curcumin_4h_R1 1 LFPIGYQCSRVYWSTTDARKR 21 3 Q03164-2;Q03164;Q03164-3 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 2 0 LFPIGY(0.984)QCS(0.918)RVY(0.069)WS(0.013)T(0.013)T(0.003)DARKR 50.215 0.012854 5022400 1240.9 1115.1 1791.6 1410.1 1047.9 878.85 843.79 651.79 1008.7 1194.2 TRUE FALSE FALSE 1142.681456 1211.484275 1857.998272 1404.26538 1035.404477 696.5666033 867.4644765 850.5177705 898.0481336 1235.698361 0.924725234 0.980404533 1.503601794 1.136414374 0.837910375 0.563702782 0.702003421 0.688289147 0.72675352 1 10.2711109 -5.522252518 4.952197266 1.020219785 0.660309397 0.465771565 0.188892398 0.128421915 8.999165859 0.026541707 0.056950157 3.00E-06 5.522252518 -0.359910388 AVEFS(ph)SGAKSPSK ddPTM_HeLa_Curcumin_4h_R1 1 AVEFSSGAKSPSK 13 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 AVEFS(0.787)S(0.055)GAKS(0.064)PS(0.094)K 127.71 0.017245 53477000 2948.6 2437.4 2455.2 2503.8 2451.6 2792 1608.2 782.71 2820.8 2324.7 TRUE FALSE FALSE 2715.215199 2648.077995 2546.191872 2493.439939 2422.366271 2212.907728 1653.321764 1021.354676 2511.365297 2405.483152 1.128760846 1.100850776 1.058494993 1.036565123 1.007018598 0.919943142 0.687313799 0.4245944 1.044016997 1 11.23211098 -4.385674295 1.050241993 1.065011059 0.173379755 0.975241082 0.03276768 0.227779739 0.225954233 0.007611828 0.214726676 4.11E-05 4.385674295 -0.891631303 down LFPNATS(ph)PELLEDFR ddPTM_HeLa_Curcumin_4h_R1 1 LFPNATSPELLEDFR 15 0 Q7Z591-6;Q7Z591-3;Q7Z591 Q7Z591-6 AKNA AT-hook-containing transcription factor 1 0 LFPNAT(0.353)S(0.647)PELLEDFR 97.073 0.0049648 488530 232.94 267.29 270.14 183.77 358.72 160.82 0 62.703 399.02 218.26 TRUE FALSE FALSE 214.5025532 290.3933566 280.151626 183.0096084 354.4424983 127.4641192 0 81.82085605 355.2485043 225.8445188 0.949779762 1.285810956 1.240462366 0.810334514 1.569409345 0.56438881 0 0.36228843 1.572978199 1 7.81918609 -5.014720296 7.362023607 1.042687801 0.202610658 0.669603121 0.280737781 0.054594744 17.01566797 0.030028021 0.08240694 9.67E-06 5.014720296 -0.840077143 LFQLGPPS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 2 LFQLGPPSPVK 11 0 Q9NZH5-2;Q9NZH5;O95997 Q9NZH5-2 PTTG2;PTTG1 Securin-2;Securin 1 0 LFQLGPPS(1)PVK;LFQLGPPS(1)PVK ; 129.54 0.0029141 307420000 6499.3 5947.4 6748.5 5742.4 7131.6 12895.9 7925.1 3473.7 5515.6 5730.9 TRUE FALSE FALSE 5984.873547 6461.466755 6998.605347 5718.63947 7046.560328 10221.14497 8147.456977 4532.815139 4910.552479 5930.048348 1.009245321 1.089614515 1.18019364 0.964349552 1.188280418 1.723619163 1.37392758 0.764380806 0.82807967 1 12.53382815 -5.529406602 12.98422659 1.025808187 1.322617586 0.21888821 0.233834068 0.476849896 940.1925853 0.031403648 0.063635142 2.96E-06 5.529406602 0.296809399 LFQSDTNAMLGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 LFQSDTNAMLGKK 13 1 F8VTR4;F8W0J4;F8W1B9;O95619 F8VTR4 YEATS4 YEATS domain-containing protein 4 0 1 ; LFQSDTNAMLGK(1)K;LFQSDTNAMLGK(1)K 220.23 2.05E-28 2173640 837.27 593.47 666.62 729.99 887.07 1040.68 959.62 844.18 1061.67 837.44 FALSE TRUE FALSE 770.999196 644.7669023 691.3255236 726.9694948 876.4922696 824.8312371 986.5443545 1101.566596 945.2074572 866.5409777 0.889743493 0.74406972 0.797798998 0.838932622 1.011483925 0.951866396 1.138485519 1.27122274 1.090782181 1 9.759124164 -4.530415582 1.405803401 0.913657215 1.334207443 0.6009999 0.098032179 0.41176163 1.0216295 0.014454491 0.211050583 2.95E-05 4.530415582 0.420550228 LFS(ph)DEDDR ddPTM_HeLa_Curcumin_4h_R1 1 LFSDEDDR 8 0 B1B047;H0Y322;Q5TKA1;Q5TKA1-2 B1B047 LIN9 Protein lin-9 homolog 1 0 LFS(1)DEDDR 92.239 0.019596 3200000 2159.9 2404.7 2359.4 2537.6 2495.4 1614.9 2139 2624.7 2344.6 3006.8 TRUE FALSE FALSE 1988.941636 2612.551553 2446.84144 2527.100084 2465.643985 1279.951536 2199.014583 3424.958947 2087.403246 3111.286076 0.639266717 0.83970149 0.78644052 0.812236491 0.792483855 0.411389858 0.706786367 1.100817753 0.670913312 1 11.60329534 -9.47496666 1.165253186 1.002631276 0.74212813 0 0.192255448 0.559926446 1.337919727 0.119437856 0.028123419 3.35E-10 9.47496666 -0.260503147 KVSGTLDT(ph)PEKTVDSQGPTPVCTPTFLER ddPTM_HeLa_Curcumin_4h_R1 1 KVSGTLDTPEKTVDSQGPTPVCTPTFLER 29 2 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 0 KVS(0.066)GT(0.066)LDT(0.631)PEKT(0.165)VDS(0.066)QGPT(0.005)PVCTPTFLER 52.249 0.0039214 67716000 1373.3 1275.4 1159.2 1519.8 1019.4 1661.2 888.35 378.47 1730.9 1189.8 TRUE FALSE FALSE 1264.601856 1385.639893 1202.160972 1513.51147 1007.244321 1316.648394 913.2747101 493.8637607 1541.0246 1231.145461 1.027175013 1.125488365 0.976457299 1.229352272 0.818135917 1.069449903 0.74180894 0.401141682 1.251699859 1 10.26578551 -4.384812967 1.89542658 1.025143152 0.288317763 0.732544201 0.124900406 0.182761682 0.820513118 0.012941097 0.215737071 4.12E-05 4.384812967 -0.736825389 down LFVGGIKEDTEEHHLR ddPTM_HeLa_Curcumin_4h_R1 2 LFVGGIKEDTEEHHLR 16 1 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 ; ; 81.185 0.0027809 352630000 11397.4 9314.2 9684.3 10082.4 9152 13071.2 10926.3 10481.1 11142.8 9657.2 FALSE FALSE TRUE 10495.28376 10119.27794 10043.20868 10040.6817 9042.868377 10360.08578 11232.86257 13676.73914 9920.462718 9992.786981 1.05028595 1.012658227 1.005045809 1.004792929 0.904939572 1.036756392 1.12409707 1.368661132 0.992762353 1 13.28667139 -4.297926546 2.038719548 1.012757719 1.453516765 0.898884072 0.037555958 0.161976609 0.76702835 0.005858775 0.128099947 5.04E-05 4.297926546 0.440759046 LFVGGLK ddPTM_HeLa_Curcumin_4h_R1 2 LFVGGLK 7 0 Q13151 Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0 0 0 ; ; 109.88 0.013975 10389400 15952.9 12829 15653.5 14380.7 17355.8 18406.4 16255.3 15569.7 11867.9 12247 FALSE FALSE TRUE 14690.21113 13937.8816 16233.63248 14321.19647 17148.84342 14588.70516 16711.37997 20316.82986 10566.02106 12672.58234 1.159212127 1.099845416 1.281004301 1.130092991 1.353224068 1.151202239 1.318703601 1.603211509 0.833770165 1 13.62942292 -1 0.205907083 1.018362529 3.308894675 0.679721666 0.11308864 20.70663865 0.240798309 0.079489886 15.56657592 0.1 1 2.290532146 LFVGNLPADITEDEFKR ddPTM_HeLa_Curcumin_4h_R1 2 LFVGNLPADITEDEFKR 17 1 P23246;P23246-2 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 0 ; ; 191.44 2.70E-07 64154000 3542.3 2888.5 3338.3 2843.2 3112.9 4381.1 3066 3249.8 3718.6 3446.7 FALSE FALSE TRUE 3261.923217 3138.169069 3462.020335 2831.435592 3075.780701 3472.410475 3152.023708 4240.64906 3310.678883 3566.472568 0.914607684 0.879908371 0.970712733 0.793903651 0.862415353 0.973626015 0.883793061 1.189031733 0.928278241 1 11.80028216 -4.254430213 24.68347157 0.933943033 1.189031875 0.631030545 0.061529039 407.0422016 1433395.878 0.009540461 0.125701267 5.57E-05 4.254430213 0.255088842 LFVGSIPK ddPTM_HeLa_Curcumin_4h_R1 2 LFVGSIPK 8 0 O60506-4;O60506-3;O60506-2;O60506;B7Z645;O60506-5;O43390;B4DT28;O43390-4;O43390-3;O43390-2 O60506-4;O43390 SYNCRIP;HNRNPR Heterogeneous nuclear ribonucleoprotein Q;Heterogeneous nuclear ribonucleoprotein R 0 0 ; ; 139.68 0.0007253 9222900 9382.6 6244.7 7515.7 7922.6 7584 8584.6 7735.9 7143.5 7756 7194.7 FALSE FALSE TRUE 8639.95731 6784.464042 7794.238453 7889.81838 7493.565753 6804.057192 7952.948534 9321.520265 6905.186205 7444.715289 1.160549057 0.911312761 1.046949165 1.059787792 1.006561764 0.91394458 1.068267654 1.252098959 0.92752858 1 12.86200096 -11.60617174 12.63350043 0.42897363 1.057398043 0 0.106511202 0 0 0 0.013672813 2.48E-12 11.60617174 0.628424413 LFVLLPEQS(ph)PVSYSK ddPTM_HeLa_Curcumin_4h_R1 1 LFVLLPEQSPVSYSK 15 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 0 LFVLLPEQS(0.999)PVS(0.001)YSK 122.33 0.0011482 123990000 1071.5 974.27 1089.9 847.09 966.37 1331.1 1000.3 929.57 1091.7 1043.9 TRUE FALSE FALSE 986.6896444 1058.481558 1130.292653 843.584966 954.8466689 1055.014855 1028.365726 1212.991614 971.9432413 1080.175447 0.913453131 0.979916328 1.046397283 0.780970321 0.883973683 0.97670694 0.952035828 1.122957957 0.899801272 1 10.07704995 -4.26056601 6.408794965 0.949378618 1.12667951 0.372811363 0.070741076 0.110030501 25.86059242 0.009868559 0.083840446 5.49E-05 4.26056601 0.177300892 LFVLLPEQS(ph)PVSYSKR ddPTM_HeLa_Curcumin_4h_R1 2 LFVLLPEQSPVSYSKR 16 1 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 0 LFVLLPEQS(0.999)PVSYSKR;LFVLLPEQS(0.994)PVS(0.003)YS(0.003)KR ; 107.18 0.00086274 26082000 7802 4961 5665.1 5506.6 4320.4 7818.6 5332 5748.5 8023.8 7071.7 TRUE FALSE FALSE 7184.463467 5389.806734 5875.05359 5483.815148 4268.882052 6196.934226 5481.60157 7501.191187 7143.609215 7317.441049 0.981827311 0.736569888 0.802883624 0.749417059 0.58338455 0.846871766 0.749114552 1.025111256 0.976244177 1 12.8371235 -7.270615023 22.71204428 0.991418478 0.777374217 0.43893694 0.103984313 113.1358207 280039.1807 0.016909006 0.01950557 5.36E-08 7.270615023 -0.214044262 LFVTNDAATILR ddPTM_HeLa_Curcumin_4h_R1 1 LFVTNDAATILR 12 0 P50990-2;P50990;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 0 0 126.71 0.00061576 995590 140.33 82.382 0 0 76.617 274.92 150.01 171.27 0 71.482 FALSE FALSE TRUE 129.2227324 89.50273299 0 0 75.70339232 217.898493 154.2188769 223.4894346 0 73.96599418 1.74705598 1.210052457 0 0 1.023489147 2.945927996 2.084997012 3.021515996 0 1 6.20879024 -9.571427032 1.301769293 0.995608921 1.484671843 0.090714242 1.03290104 1.797873501 5.381598696 0.787718156 0.177676192 2.68E-10 9.571427032 0.489062921 LGADES(ph)EEEGR ddPTM_HeLa_Curcumin_4h_R1 2 LGADESEEEGR 11 0 O43847;O43847-2;F5H7V1 O43847 NRD1 Nardilysin 1 0 LGADES(1)EEEGR;LGADES(1)EEEGR ; 108.68 0.0071989 42980000 7276.2 9239.9 8218.5 7500.9 7169.7 9048.2 7430.5 5548.4 9381.7 11224.1 TRUE FALSE FALSE 6700.281092 10038.55578 8523.08484 7469.863263 7084.20601 7171.501326 7638.979832 7240.081618 8352.550982 11614.13664 0.576907376 0.86433939 0.733854363 0.643169914 0.609964066 0.617480365 0.657731183 0.623385263 0.719171062 1 13.50359429 -9.440452025 0.856604971 1.029761028 0.66092696 0.159026312 0.115730842 0.332810816 0.376690483 0.086495517 0.01573013 3.63E-10 9.440452025 -0.368834068 LGAESPS(ph)IASTSSTEK ddPTM_HeLa_Curcumin_4h_R1 1 LGAESPSIASTSSTEK 16 0 A0A0D9SF60;Q99569-2;Q99569;H0YFB1;E7EST6 A0A0D9SF60 PKP4 Plakophilin-4 1 0 LGAES(0.308)PS(0.653)IAS(0.029)T(0.008)SSTEK 138.81 2.85E-05 0 1683.2 1487.2 1438.5 1352.7 1455.5 1882.5 1115 825.06 1860.6 1439.6 TRUE FALSE FALSE 1549.972944 1615.746941 1491.812075 1347.102886 1438.144113 1492.04828 1146.283899 1076.616996 1656.496835 1489.625993 1.040511478 1.084666184 1.001467538 0.904322892 0.965439728 1.001626104 0.769511209 0.722743159 1.112021973 1 10.54073444 -4.040639508 0.705260942 1.020627532 0.403038201 0.766340097 0.058385983 1.169499734 0.329908831 0.008695067 0.616454447 9.11E-05 4.040639508 -0.61758933 LGAGEGGEAS(ph)VS(ph)PEKTSTTSK ddPTM_HeLa_Curcumin_4h_R1 1 LGAGEGGEASVSPEKTSTTSK 21 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 2 0 LGAGEGGEAS(0.796)VS(0.759)PEKT(0.183)S(0.136)T(0.071)T(0.041)S(0.015)K 65.022 0.0040271 32687000 3287.5 2488.6 2373.5 2494.2 2443.4 2771.5 2261.3 1244.3 2955.3 2078.3 TRUE FALSE FALSE 3027.290906 2703.703495 2461.463998 2483.879661 2414.264051 2196.659659 2324.745992 1623.681342 2631.110984 2150.52077 1.40770131 1.257231984 1.144589735 1.1550131 1.122641587 1.021454751 1.081015363 0.755017745 1.223476202 1 11.07047035 -3.58240708 0.711196296 1.195400935 4.42E-12 0.606918638 0.103570453 5.082383819 0.914270651 0.025988054 6.122716572 0.000261573 3.58240708 -1.195400935 SHS(ph)TEPNLSSFLNDPNPMK ddPTM_HeLa_Curcumin_4h_R1 1 SHSTEPNLSSFLNDPNPMK 19 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 S(0.058)HS(0.68)T(0.262)EPNLSSFLNDPNPMK 73.404 0.0049175 12945000 1555.6 1034.2 1158.3 1211.8 1468.5 2228.7 2521.9 14288 0 1052.6 TRUE FALSE FALSE 1432.472619 1123.59164 1201.227617 1206.785893 1450.989097 1766.442497 2592.657727 18644.34543 0 1089.177772 1.315187158 1.03159619 1.102875626 1.107978811 1.332187577 1.621812842 2.380380682 17.11781668 0 1 10.08902373 -4.257005543 4.01737243 1.192313875 18.60347467 0.99247612 0.416781189 0.008454843 0.283066969 0.035465183 0.428904731 5.53E-05 4.257005543 17.4111608 up LGAGEGGEASVS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 4 LGAGEGGEASVSPEK 15 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 LGAGEGGEAS(0.01)VS(0.99)PEK;LGAGEGGEAS(0.065)VS(0.935)PEK;LGAGEGGEAS(0.007)VS(0.993)PEK;LGAGEGGEAS(0.212)VS(0.788)PEK ;;; 189.8 2.84E-06 638786000 12683.5 11829.2 12212.6 12964.4 14293 12385.8 10954.1 8446.14 11237.7 9913 TRUE FALSE FALSE 11679.58759 12851.66334 12665.2097 12910.75675 14122.56531 9816.845463 11261.44256 11021.3292 10004.95243 10257.47601 1.138641473 1.252906984 1.234729643 1.258667993 1.376807052 0.957042985 1.097876568 1.074467948 0.975381508 1 13.32438816 -8.536244274 0.916735075 1.014645529 1.177295855 0.299239258 0.111688925 0.544764846 0.937028539 0.04544747 0.02425738 2.91E-09 8.536244274 0.162650326 LGAGEGGEASVS(ph)PEKTSTTSK ddPTM_HeLa_Curcumin_4h_R1 4 LGAGEGGEASVSPEKTSTTSK 21 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 LGAGEGGEAS(0.044)VS(0.941)PEKT(0.009)S(0.004)T(0.001)TSK;LGAGEGGEAS(0.002)VS(0.974)PEKT(0.017)S(0.006)T(0.001)TSK;LGAGEGGEAS(0.003)VS(0.892)PEKT(0.075)S(0.022)T(0.007)T(0.001)SK;LGAGEGGEAS(0.001)VS(0.998)PEKTSTTSK ;;; 131.33 6.02E-06 2249750000 18025 20026.7 15092.8 17171 14640.9 18366 15414.6 11548.9 19123.9 15867.3 TRUE FALSE FALSE 16598.30223 21757.71871 15652.15244 17099.95095 14466.31683 14556.68457 15847.09219 15070.10645 17026.05602 16418.68749 1.010939653 1.325180147 0.953313257 1.041493174 0.881088506 0.886592462 0.965186297 0.917863042 1.036992514 1 14.00305118 -5.768171775 24.7873128 1.029903484 0.91456926 0.322389607 0.099483365 160.2105444 589865.3514 0.014840476 0.027353615 1.71E-06 5.768171775 -0.115334224 LGAGGGS(ph)PEKSPSAQELK ddPTM_HeLa_Curcumin_4h_R1 1 LGAGGGSPEKSPSAQELK 18 1 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 0 LGAGGGS(0.935)PEKS(0.053)PS(0.012)AQELK 72.145 0.0054438 1579800000 4258.3 3778.6 3955.3 3930.7 3462.4 4297.2 3778.6 3231.5 3982.8 3391.3 TRUE FALSE FALSE 3921.251062 4105.205347 4101.886897 3914.435805 3421.113141 3405.912281 3884.617346 4216.769474 3545.896804 3509.147423 1.11743697 1.169858331 1.168912674 1.115494829 0.974912915 0.970581133 1.106997478 1.201650705 1.010472453 1 11.77690484 -9.243880939 1.051823094 1.001768517 1.099695986 0.221599636 0.072907282 0.703280588 1.43175029 0.048833795 0.01442635 5.70E-10 9.243880939 0.097927468 LGAGGGS(ph)PEKSPSAQELKEQGNR ddPTM_HeLa_Curcumin_4h_R1 2 LGAGGGSPEKSPSAQELKEQGNR 23 2 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 0 LGAGGGS(0.983)PEKS(0.017)PSAQELKEQGNR;LGAGGGS(0.797)PEKS(0.186)PS(0.018)AQELKEQGNR ; 73.984 0.00034738 142194000 6254.6 3891.8 3494.2 4409.2 2028.01 5794.9 2983.3 3297.6 8646.4 6578.2 TRUE FALSE FALSE 5759.54181 4228.18985 3623.698126 4390.955899 2003.827305 4592.972418 3067.003369 4303.02306 7697.911552 6806.79196 0.846146297 0.621172187 0.532365048 0.645084487 0.294386448 0.674763155 0.45057986 0.63216609 1.130916237 1 12.7327593 -7.344601055 1.074257736 0.956525559 0.522669583 0.74384436 0.120129988 0.147855215 0.336154758 0.021664377 0.024732342 4.52E-08 7.344601055 -0.433855976 LGAGGGSPEKSPS(ph)AQELK ddPTM_HeLa_Curcumin_4h_R1 3 LGAGGGSPEKSPSAQELK 18 1 Q9UNE7;H3BS86 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 0 LGAGGGS(0.215)PEKS(0.231)PS(0.554)AQELK;LGAGGGS(0.006)PEKS(0.031)PS(0.963)AQELK;LGAGGGS(0.061)PEKS(0.12)PS(0.819)AQELK ;; 80.411 0.0027386 345611000 7294.85 10494.3 7307.69 8599.8 8057.19 8764.38 7933.38 6317.84 7961.01 7238.4 TRUE FALSE FALSE 6717.454925 11401.38053 7578.51942 8564.216306 7961.113272 6946.548793 8155.969291 8244.120332 7087.70712 7489.933861 0.896864385 1.522227131 1.011827282 1.143430164 1.062908354 0.927451286 1.088924074 1.100693342 0.946297691 1 12.87073726 LGAHEGLS(ph)PTPFMNSNLMGK ddPTM_HeLa_Curcumin_4h_R1 1 LGAHEGLSPTPFMNSNLMGK 20 0 Q99081;Q99081-3;B4DGI9;H0YNQ5 Q99081 TCF12 Transcription factor 12 1 0 LGAHEGLS(0.896)PT(0.104)PFMNSNLMGK 118.46 5.92E-05 20319000 1687.7 1439.2 1653.6 1627.4 1507.9 2545.5 2004.5 2886.7 1854.3 1566.7 TRUE FALSE FALSE 1554.116764 1563.598035 1714.883871 1620.66625 1489.919277 2017.534606 2060.740875 3766.841541 1650.887929 1621.142708 0.958655124 0.964503635 1.057824127 0.999706097 0.919054979 1.244513883 1.271165619 2.323571837 1.018348305 1 10.66279538 LGAHEGLSPT(ph)PFMNSNLMGK ddPTM_HeLa_Curcumin_4h_R1 1 LGAHEGLSPTPFMNSNLMGK 20 0 Q99081;Q99081-3;B4DGI9;H0YNQ5 Q99081 TCF12 Transcription factor 12 1 0 LGAHEGLS(0.414)PT(0.586)PFMNSNLMGK 97.095 0.00069035 23257000 1841.7 1455.8 1623 1482.2 1660.3 2160.4 1838.1 2908.2 1558.4 1986.2 TRUE FALSE FALSE 1695.927502 1581.632865 1683.149808 1476.067049 1640.502007 1712.308687 1889.672139 3794.896792 1387.447419 2055.220302 0.825180395 0.769568529 0.818963206 0.718203809 0.798212243 0.833150921 0.919449918 1.846467159 0.675084524 1 11.00507733 -4.261516774 4.998620283 0.871011549 1.894537408 0.902661037 0.100112419 0.03998096 3.092248985 0.014770768 0.140939654 5.48E-05 4.261516774 1.023525859 LGAPENSGIST(ph)LER ddPTM_HeLa_Curcumin_4h_R1 4 LGAPENSGISTLER 14 0 A0A1B0GV68;M0QYB0;Q9Y4F1-3;C9JME2;Q9Y4F1;Q9Y4F1-2 A0A1B0GV68;C9JME2 FARP1 "FERM, RhoGEF and pleckstrin domain-containing protein 1" 1 0 LGAPENSGIS(0.001)T(0.999)LER;LGAPENSGIS(0.025)T(0.975)LER;LGAPENS(0.001)GIS(0.087)T(0.912)LER;LGAPENSGIS(0.028)T(0.972)LER ;;; 216 2.27E-13 180224000 16881.6 12411.5 12523.9 17612.8 14410.4 21242.7 12169.2 10972.9 20594.1 13075.2 TRUE FALSE FALSE 15545.40355 13484.29476 12988.04675 17539.9229 14238.56539 16836.72457 12510.635 14318.4867 18334.97875 13529.56223 1.14899531 0.996654181 0.959975388 1.296414666 1.052403999 1.244439715 0.924688825 1.05831116 1.355179011 1 13.72382754 -9.599986523 1.386079137 0.999827028 1.093043274 0 0.157678909 0.891665202 3.06457977 0.07730637 0.017728838 2.51E-10 9.599986523 0.093216246 LGAQT(ph)PVGVSTLEPGQTLLPR ddPTM_HeLa_Curcumin_4h_R1 1 LGAQTPVGVSTLEPGQTLLPR 21 0 O94887-3;O94887-2;O94887;C9JWM9;C9JVQ5 O94887-3 FARP2 "FERM, RhoGEF and pleckstrin domain-containing protein 2" 1 0 LGAQT(0.938)PVGVS(0.047)T(0.014)LEPGQTLLPR 132.67 8.38E-05 14465000 1078.9 885.45 734.2 952.56 746.06 778.09 697.1 409.65 1193.3 893.07 TRUE FALSE FALSE 993.5039265 961.9843525 761.4100979 948.6185591 737.1637218 616.7053631 716.6587499 534.5503992 1062.397975 924.104116 1.075099558 1.040991308 0.823944061 1.026527793 0.79770635 0.667354849 0.775517323 0.578452568 1.149651816 1 9.851911595 -5.546320306 0.770129306 1.035294642 0.61881792 0.774998442 0.085869939 0.267172328 0.264737349 0.013718337 0.066222214 2.84E-06 5.546320306 -0.416476722 SSS(ph)PIPLTPSK ddPTM_HeLa_Curcumin_4h_R1 2 SSSPIPLTPSK 11 0 Q8N5Y2;Q8N5Y2-3;Q8N5Y2-2;A0A3B3IT59;Q8N5Y2-6;Q8N5Y2-4;A0A3B3ITL5;A0A3B3ITF3;A0A3F2YNX2;A0A3B3IRN2 Q8N5Y2 MSL3 Male-specific lethal 3 homolog 1 0 S(0.001)S(0.224)S(0.775)PIPLTPSK;SS(0.005)S(0.994)PIPLTPSK ; 187.31 6.23E-05 73138000 18117.8 14983.9 16346.9 17906.3 16771.2 15902.1 11034.5 4201.7 17955.5 14916.5 TRUE FALSE FALSE 16683.75701 16279.04155 16952.73049 17832.20848 16571.21439 12603.82521 11344.09837 5482.778988 15985.82657 15434.84726 1.08091494 1.054694048 1.098341318 1.155321343 1.073623477 0.816582438 0.734966675 0.355220813 1.035697101 1 13.91390359 -4.384474857 1.162363313 1.055579544 0.136222659 0.93629962 0.058339323 0.250370247 0.319198042 0.009913558 0.263094554 4.13E-05 4.384474857 -0.919356885 down LGASNS(ph)PGQPNS(ph)VKR ddPTM_HeLa_Curcumin_4h_R1 1 LGASNSPGQPNSVKR 15 1 P49756 P49756 RBM25 RNA-binding protein 25 2 0 LGAS(0.005)NS(0.995)PGQPNS(1)VKR 87.669 0.014701 15724000 4607.7 3790.1 4193.3 4315.5 3949.8 7652.7 7520.9 2826.1 4788.2 4008.8 TRUE FALSE FALSE 4242.995683 4117.699356 4348.707387 4297.643604 3902.701215 6065.443756 7731.916213 3687.76488 4262.946439 4148.105502 1.022875547 0.992669872 1.04835988 1.036049735 0.94083943 1.462220224 1.86396325 0.889023888 1.027685154 1 12.01823687 -5.256647178 24.14197231 1.010434537 1.45095859 0.394326928 0.222325232 154.5447232 778552.8153 0.027568143 0.067782273 5.54E-06 5.256647178 0.440524053 LGASNS(ph)PGQPNSVK ddPTM_HeLa_Curcumin_4h_R1 4 LGASNSPGQPNSVK 14 0 P49756 P49756 RBM25 RNA-binding protein 25 1 0 LGAS(0.002)NS(0.547)PGQPNS(0.45)VK;LGAS(0.016)NS(0.963)PGQPNS(0.022)VK;LGAS(0.009)NS(0.661)PGQPNS(0.33)VK;LGAS(0.014)NS(0.966)PGQPNS(0.02)VK ;;; 142.19 0.000712 109927700 15052.7 13537.7 14695.52 13897.83 15100.22 16925.5 14147.28 8290.3 16733.9 14451.8 TRUE FALSE FALSE 13861.26291 14707.83847 15240.1489 13840.32446 14920.15974 13414.96051 14544.2146 10817.97431 14898.23304 14953.99897 0.926926833 0.983538817 1.019135345 0.925526642 0.997737111 0.897081813 0.972597004 0.723416815 0.996270834 1 13.86824372 -4.260331385 24.96423499 0.964909217 0.723416736 0.791521436 0.037727216 32.04985507 722018.9816 0.005327889 0.043975321 5.49E-05 4.260331385 -0.241492481 LGASNS(ph)PGQPNSVKR ddPTM_HeLa_Curcumin_4h_R1 2 LGASNSPGQPNSVKR 15 1 P49756 P49756 RBM25 RNA-binding protein 25 1 0 LGAS(0.075)NS(0.925)PGQPNSVKR;LGAS(0.004)NS(0.996)PGQPNSVKR ; 98.077 0.0021657 57708000 4702.1 4031.6 4312.1 4313 4053.3 5347.5 4651.4 2486.2 5421.1 5186.3 TRUE FALSE FALSE 4329.923823 4380.07354 4471.910219 4295.153949 4004.967045 4238.368221 4781.905765 3244.230935 4826.418893 5366.523539 0.806839622 0.816184539 0.83329742 0.800360591 0.746287054 0.789779117 0.891062106 0.604531204 0.899356699 1 12.38977209 -13.52287875 0.172283585 1.885212984 0.734610585 0.446278418 0.07338449 26.58483476 0.297347379 7.865593265 0.09565054 3.00E-14 13.52287875 -1.150602398 LGASNSPGQPNS(ph)VK ddPTM_HeLa_Curcumin_4h_R1 1 LGASNSPGQPNSVK 14 0 P49756 P49756 RBM25 RNA-binding protein 25 1 0 LGAS(0.001)NS(0.427)PGQPNS(0.573)VK 158.65 0.00032804 770330000 14972 11984 13810 13473 14009 14904 13126 6033.5 13077 11236 TRUE FALSE FALSE 13786.9504 13019.84356 14321.81075 13417.2523 13841.95182 11812.7424 13494.28023 7873.086375 11642.48582 11626.45016 1.185826302 1.119846847 1.231830055 1.154028281 1.190557017 1.01602314 1.160653514 0.677170268 1.001379239 1 13.50512305 -4.257403664 24.59276575 1.111266258 0.677170053 0.730722367 0.080155956 144.4642526 880288.6681 0.012370317 0.126498132 5.53E-05 4.257403664 -0.434096206 LGDASDT(ph)EAADGER ddPTM_HeLa_Curcumin_4h_R1 2 LGDASDTEAADGER 14 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 0 LGDAS(0.13)DT(0.87)EAADGER;LGDAS(0.281)DT(0.719)EAADGER ; 156.2 0.001095 108875000 3918.6 2658.91 3031.6 3342.4 3117.9 3986.6 2235.45 1722.49 4252.6 3614.9 TRUE FALSE FALSE 3608.438675 2888.734333 3143.953763 3328.570034 3080.721079 3159.734222 2298.170711 2247.669272 3786.100419 3740.517506 0.964689691 0.772281998 0.840513046 0.889868856 0.82360825 0.844731836 0.614399132 0.600897942 1.012186259 1 11.86902217 -3.254614069 0.253230978 1.011717388 2.75E-17 0.785434378 0.063188939 5.242692443 0.17473934 0.04011046 1.809339305 0.000556398 3.254614069 -1.011717388 LGDDEDREPSLRPDDDRVPR ddPTM_HeLa_Curcumin_4h_R1 2 LGDDEDREPSLRPDDDRVPR 20 3 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 ; ; 50.966 0.0091087 40273000 5466.7 4775.6 5414.1 5392.2 5680.6 5734.7 3966.9 5052.1 4884.2 4251 FALSE FALSE TRUE 5034.004927 5188.381584 5614.751309 5369.888505 5612.862555 4545.258577 4078.200538 6592.462033 4348.41548 4398.721934 1.144424449 1.179520248 1.276450613 1.220783806 1.276021226 1.033313459 0.927133063 1.498722159 0.988563393 1 12.10286869 -8.545619738 0.718506701 1.006634114 1.189450306 0.235361942 0.143959986 0.788230836 0.833326417 0.071581703 0.03202739 2.85E-09 8.545619738 0.182816192 LGDEDEEIDGDTNK ddPTM_HeLa_Curcumin_4h_R1 1 LGDEDEEIDGDTNK 14 0 A0A087WU64;A6NMQ1;P09884 A0A087WU64 POLA1 DNA polymerase;DNA polymerase alpha catalytic subunit 0 0 210.35 1.23E-08 5375700 1513.9 1037.4 1012 1273.7 1051.2 1505 953.71 784.46 1262.5 950.88 FALSE FALSE TRUE 1394.073218 1127.068233 1049.50561 1268.429767 1038.665127 1192.846035 980.4685358 1023.638243 1124.006909 983.9230092 1.416851933 1.145484172 1.0666542 1.289155508 1.055636586 1.212336762 0.996489082 1.040364168 1.142372826 1 9.942401621 -4.755422293 1.093789229 1.19020566 0.986328456 0.139610814 0.119747328 1.468380818 2.315554173 0.025356558 0.281416881 1.76E-05 4.755422293 -0.203877204 LGDLYEEEMR ddPTM_HeLa_Curcumin_4h_R1 4 LGDLYEEEMR 10 0 P08670;B0YJC4 P08670 VIM Vimentin 0 0 ;;; ;;; 223.32 3.29E-10 535032100 11220.1 9415 9969.1 10471.3 10657.7 11698.9 9701.3 9561.6 11033.5 10257.8 FALSE FALSE TRUE 10332.01725 10228.79065 10338.56362 10427.97254 10530.61389 9272.416266 9973.492368 12476.88782 9823.152654 10614.25779 0.9734093 0.963684023 0.974026053 0.982449526 0.992119666 0.87358122 0.939631632 1.175483776 0.925467692 1 13.37371587 -9.29028174 1.061916954 0.999768238 0.978105434 0 0.075632958 2.794586825 5.734396019 0.043977628 0.012338178 5.13E-10 9.29028174 -0.021662804 LGDS(ph)SLSR ddPTM_HeLa_Curcumin_4h_R1 1 LGDSSLSR 8 0 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 0 LGDS(0.728)S(0.272)LSR 95.358 0.01777 7771500 5335.4 4903.2 5156.2 5479 5605.3 6508.1 4374.2 5349.3 5576 5630.7 TRUE FALSE FALSE 4913.09746 5327.01076 5347.293308 5456.32935 5538.460458 5158.246699 4496.928279 6980.276945 4964.32675 5826.366406 0.843252401 0.914293813 0.917774979 0.936489223 0.950585678 0.885328237 0.771823803 1.198049772 0.852045066 1 12.50838072 -6.249492847 20.12944949 0.922478263 0.935253768 0.019480531 0.107627387 617.3093024 1040113.808 0.016153439 0.026565027 5.63E-07 6.249492847 0.012775505 LGDSHDLQR ddPTM_HeLa_Curcumin_4h_R1 3 LGDSHDLQR 9 0 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 ;; ;; 152.06 0.0012364 30865590 13935.7 10817.8 12350.9 11860.5 13614.2 16355.5 12991.9 12830.3 13846 12201.4 FALSE FALSE TRUE 12832.67464 11752.84243 12808.63522 11811.42439 13451.85956 12963.18494 13356.41775 16742.19941 12327.12844 12625.39774 1.016417455 0.930888885 1.014513402 0.935528895 1.06546026 1.026754578 1.057900751 1.326073027 0.976375453 1 13.62404122 -2.80620739 1.115730634 1.000201798 8.394723975 0.869423078 0.038311094 8.706285049 0.57807506 0.005344955 147.441306 0.001562401 2.80620739 7.394522177 LGDSS(ph)LSR ddPTM_HeLa_Curcumin_4h_R1 3 LGDSSLSR 8 0 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 0 LGDS(0.268)S(0.732)LSR;LGDS(0.04)S(0.96)LSR;LGDS(0.044)S(0.956)LSR ;; 142.36 0.0027861 292522900 14361 14320.5 15294.6 16612.9 15171.8 17605.4 12507.1 13977 15379.6 15557.1 TRUE FALSE FALSE 13224.3117 15558.30021 15861.43133 16544.16022 14990.88619 13953.84159 12858.01556 18238.52296 13692.49636 16097.70807 0.821502766 0.966491636 0.985322337 1.027733896 0.931243512 0.866821633 0.798748214 1.132988801 0.850586698 1 13.97456768 -4.23692644 23.52012398 0.921562445 1.132989371 0.425112773 0.075320584 2813.826347 2699768.619 0.012010108 0.921473109 5.80E-05 4.23692644 0.211426926 SSS(ph)SGSDDYAYTQALLLHQR ddPTM_HeLa_Curcumin_4h_R1 2 SSSSGSDDYAYTQALLLHQR 20 0 F6SS63;Q8N5C8-2;Q8N5C8 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 0 S(0.265)S(0.265)S(0.397)S(0.072)GSDDYAYTQALLLHQR;S(0.117)S(0.117)S(0.569)S(0.147)GS(0.049)DDYAYTQALLLHQR ; 208.87 2.11E-14 32187000 1815.07 1432.9 1706.43 1778.19 1841.97 2323.5 2103.78 4525.2 1599.13 1921.34 TRUE FALSE FALSE 1671.405294 1556.753491 1769.671797 1770.832321 1820.005711 1841.579909 2162.806405 5904.912649 1423.70944 1988.106422 0.840702125 0.783033279 0.89012931 0.890713043 0.915446825 0.926298456 1.087872551 2.970118995 0.716113295 1 10.95717927 -4.256996871 3.824133067 0.909411005 3.185534145 0.982976831 0.082255888 0.020976022 0.591584001 0.01055019 0.134342037 5.53E-05 4.256996871 2.27612314 up LGDVS(ph)PTQIDVSQFGSFKEDTK ddPTM_HeLa_Curcumin_4h_R1 3 LGDVSPTQIDVSQFGSFKEDTK 22 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 LGDVS(0.757)PT(0.242)QIDVSQFGSFKEDTK;LGDVS(0.958)PT(0.042)QIDVSQFGSFKEDTK;LGDVS(0.5)PT(0.5)QIDVSQFGSFKEDTK ;; 149.3 3.42E-06 317196400 5672.62 4616.08 4356.76 4971.3 4561.99 6051.08 4607.06 6789.15 6094.51 5371.73 TRUE FALSE FALSE 5223.626141 5015.073386 4518.225358 4950.730078 4507.591249 4796.017798 4736.321704 8859.130582 5425.957501 5558.397218 0.939772013 0.902251709 0.812864785 0.890675834 0.810951624 0.862841861 0.852102057 1.593828263 0.976173038 1 12.44045322 -4.257547939 24.99174291 0.926509091 1.593828521 0.904021806 0.067656686 105.8417509 679712.7338 0.01162828 0.117619019 5.53E-05 4.257547939 0.66731943 LGDVYVNDAFGTAHR ddPTM_HeLa_Curcumin_4h_R1 4 LGDVYVNDAFGTAHR 15 0 P00558;P00558-2;P07205 P00558 PGK1;PGK2 Phosphoglycerate kinase 1;Phosphoglycerate kinase 2 0 0 ;;; ;;; 247.17 4.77E-49 376055600 17606.3 13602.7 13837.2 14321.2 15255.4 22031.5 16348.7 16917.6 16734.2 15021.6 FALSE FALSE TRUE 16212.74278 14778.45678 14350.0188 14261.94267 15073.48932 17461.91855 16807.40052 22075.69836 14898.50013 15543.59948 1.043049443 0.95077442 0.923210793 0.917544401 0.969755386 1.123415369 1.081306845 1.420243643 0.958497428 1 13.92403301 -3.489645118 1.093382716 0.99962677 2.936915537 0.850456666 0.055099802 2.375734681 0.662604377 0.009036727 8.016567409 0.000323858 3.489645118 1.937288767 LGEAS(ph)DSELADADK ddPTM_HeLa_Curcumin_4h_R1 4 LGEASDSELADADK 14 0 H0Y2V6;Q5SW79;Q5SW79-3;Q5SW79-2 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 0 LGEAS(0.996)DS(0.004)ELADADK;LGEAS(0.662)DS(0.338)ELADADK;LGEAS(0.997)DS(0.003)ELADADK;LGEAS(0.974)DS(0.026)ELADADK ;;; 280.5 3.23E-63 172226000 13995.3 14512.9 15201.8 13950.4 16317 15232.3 11417.1 5807.2 13011.2 11356.4 TRUE FALSE FALSE 12887.55724 15767.33041 15765.19208 13892.67694 16122.43043 12072.94928 11737.4331 7577.788547 11583.90391 11751.03405 1.096716866 1.341782377 1.341600408 1.182251441 1.372000996 1.027394629 0.998842574 0.644861423 0.98577741 1 13.52050009 -4.231681367 1.868731633 1.121292764 0.472832432 0.539286044 0.142908167 0.666356097 2.220738862 0.023410038 0.769590394 5.87E-05 4.231681367 -0.648460332 LGELTMQLHPVADS(ph)SPAGAQIK ddPTM_HeLa_Curcumin_4h_R1 2 LGELTMQLHPVADSSPAGAQIK 22 0 Q8IXM2-2 Q8IXM2-2 BAP18 Chromatin complexes subunit BAP18 1 0 LGELTMQLHPVADS(0.617)S(0.383)PAGAQIK;LGELTMQLHPVADS(0.57)S(0.43)PAGAQIK ; 115.38 3.89E-06 65650000 2694.9 2156.43 2042.55 2550.74 2468.71 2878.5 2257.29 1713.36 2967.2 2759.28 TRUE FALSE FALSE 2481.595821 2342.8222 2118.2487 2540.185714 2439.272246 2281.466653 2320.623482 2235.755577 2641.705584 2855.164775 0.869160282 0.820555865 0.741900684 0.889680952 0.854336768 0.799066545 0.81278093 0.783056585 0.925237523 1 11.47935829 -8.532023169 0.521073016 1.009694203 0.810149451 0.614435365 0.04440154 0.352829343 0.193090356 0.032474695 0.0119258 2.94E-09 8.532023169 -0.199544752 LGERDDTIPPEYR ddPTM_HeLa_Curcumin_4h_R1 1 LGERDDTIPPEYR 13 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E7EVY3;E9PCH5;P20810-3;E7EQ12;E7EQA0;H0Y7F0;A0A0A0MR45;H0Y9H6;H0YD33;A0A0C4DGD1 P20810-6 CAST Calpastatin 0 0 104.59 0.0044898 7351300 2243.6 1725.9 1893.9 1811 1688.5 2413.5 1530.4 1182.7 2446.1 2041.7 FALSE FALSE TRUE 2066.016693 1875.079106 1964.0896 1803.506562 1668.36574 1912.912894 1573.338905 1543.299786 2177.76895 2112.648923 0.977927127 0.887548842 0.929681017 0.853670736 0.789703259 0.905457065 0.744723313 0.730504614 1.030823875 1 11.04483733 -4.938866266 0.294946407 1.013604965 0.594377039 0.820951584 0.042135126 1.527210497 0.135175201 0.021518376 0.221369992 1.15E-05 4.938866266 -0.419227926 LGEVTGSPS(ph)PPPR ddPTM_HeLa_Curcumin_4h_R1 1 LGEVTGSPSPPPR 13 0 O94875-12;O94875-5;O94875-3;H7BXR3;O94875-4;H7BZX1;O94875-10 O94875-12;O94875-10 SORBS2 Sorbin and SH3 domain-containing protein 2 1 0 LGEVT(0.031)GS(0.111)PS(0.859)PPPR 105.66 0.0049781 8514100 2872.4 2088.1 2645.8 2673.1 2224.1 3603.6 4481 2172 2637.1 2429.6 TRUE FALSE FALSE 2645.046509 2268.58606 2743.855675 2662.03942 2197.57906 2856.172739 4606.7248 2834.232801 2347.816728 2514.028419 1.052114801 0.902370889 1.091417923 1.058874037 0.874126578 1.136094054 1.832407607 1.12736705 0.933886312 1 11.29578524 -4.980819719 23.59900996 1.014468849 1.480978964 0.5571149 0.172284205 57.2579551 70447.0934 0.020030377 0.060073925 1.05E-05 4.980819719 0.466510115 LGEYEDVSR ddPTM_HeLa_Curcumin_4h_R1 1 LGEYEDVSR 9 0 K7EP07;K7EK42;A0A494C0X0;Q99426-2;Q99426;K7EL99 K7EP07 TBCB Tubulin-folding cofactor B 0 0 154.12 0.011509 33707000 2411.4 1906.6 1990.7 2173.6 1964.2 2463 2204.8 2072.3 2485.7 1947.6 FALSE FALSE TRUE 2220.535146 2071.398008 2064.477093 2164.606219 1940.778198 1952.146036 2266.660754 2704.13473 2213.024929 2015.278955 1.101850014 1.027846792 1.02441257 1.074097565 0.963032037 0.968672864 1.124737967 1.341816588 1.098123376 1 10.97676384 -4.334181158 3.071442071 1.037543659 1.366333929 0.799285415 0.046796676 0.109010197 1.603917926 0.007197592 0.078201088 4.63E-05 4.334181158 0.328790269 LGFEEFK ddPTM_HeLa_Curcumin_4h_R1 1 LGFEEFK 7 0 U3KPR7;U3KQE2;K7EIV0;A0A075B7C0;K7EKD8;K7ELJ7;A0A0C4DGQ5;Q96L46;P04632 U3KPR7 CAPNS1;CAPNS2 Calpain small subunit 2;Calpain small subunit 1 0 0 102.71 0.018962 2318700 4161.4 3433.5 4011.3 3472.3 3572.3 3456.9 3498.7 2876 3615.1 3093.7 FALSE FALSE TRUE 3832.020799 3730.276441 4159.962307 3457.932543 3529.702656 2739.899973 3596.864106 3752.879161 3218.532575 3201.205845 1.197055417 1.165272282 1.299498535 1.080196873 1.102616585 0.855896217 1.123596632 1.172332972 1.005412563 1 11.64439973 -4.516672424 24.95506679 1.098008909 1.160148942 0.043291133 0.114986076 796.5605824 3202851.317 0.017272326 0.069626128 3.04E-05 4.516672424 0.062140033 LGFSLT(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 LGFSLTPSK 9 0 P38432 P38432 COIL Coilin 1 0 LGFSLT(0.999)PS(0.001)K 163.84 0.001203 193340000 8813.6 7019.2 8223.6 8502.8 8189.1 9753.5 8012.7 1050.5 7401.2 6684 TRUE FALSE FALSE 8115.99426 7625.908371 8528.37385 8467.617667 8091.450331 7730.514155 8237.514797 1370.792614 6589.306877 6916.268502 1.173464312 1.102604442 1.23308889 1.224304358 1.169915588 1.11772904 1.191034558 0.198198293 0.952725718 1 12.75577816 -4.258678781 24.99858821 1.118100515 0.198197964 0.909965565 0.087811026 56.44260479 511087.2471 0.012879751 0.118986859 5.51E-05 4.258678781 -0.919902551 LGFSS(ph)SPTK ddPTM_HeLa_Curcumin_4h_R1 1 LGFSSSPTK 9 0 Q8IVF2;Q8IVF2-3;Q8IVF2-2 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 LGFS(0.069)S(0.64)S(0.287)PT(0.004)K 99.815 0.013239 72517000 3867.1 2950.4 3062.4 3283.3 4198.9 4535.7 3737.9 2454.6 4179.3 2846.8 TRUE FALSE FALSE 3561.014954 3205.419429 3175.895238 3269.714575 4148.83086 3594.944692 3842.775414 3202.99624 3720.841246 2945.726088 1.208875112 1.088159365 1.078136644 1.109985951 1.408423844 1.220393405 1.304525709 1.087336753 1.263132123 1 11.52440757 -5.955447024 24.89558662 1.098585239 1.256585784 0.260263806 0.102368736 107.4334373 60031.79769 0.015030278 0.027244681 1.11E-06 5.955447024 0.158000546 LGFSS(ph)SPTKK ddPTM_HeLa_Curcumin_4h_R1 1 LGFSSSPTKK 10 1 Q8IVF2;Q8IVF2-3;Q8IVF2-2 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 LGFS(0.01)S(0.917)S(0.073)PTKK 124.67 0.0059195 350390000 4054.9 3033.6 3112.3 3953.8 3072.1 3851.5 2982.2 1908.9 3728.7 2783.2 TRUE FALSE FALSE 3733.950386 3295.810867 3227.644576 3937.440223 3035.467214 3052.655485 3065.872506 2490.914823 3319.670939 2879.915993 1.29654837 1.144412155 1.120742613 1.367206624 1.054012416 1.05998074 1.064570117 0.864926209 1.152697144 1 11.49181101 -3.907710485 0.9637218 1.152872326 0.5300006 0.436451565 0.101795614 3.388744765 1.520560113 0.019985382 2.576510088 0.000123677 3.907710485 -0.622871726 LGFSSPYEGVLNKS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 LGFSSPYEGVLNKSPK 16 1 M0R0P8;Q13459-2;Q13459;M0R240;M0QXP0 M0R0P8 MYO9B Unconventional myosin-IXb 1 0 LGFSSPY(0.002)EGVLNKS(0.998)PK;LGFSSPYEGVLNKS(1)PK ; 75.564 0.00768 73010000 3965.1 3053.2 3358.1 4353.4 3193.2 4090.6 2560.2 3605.8 4188.9 3987.1 TRUE FALSE FALSE 3651.258151 3317.105003 3482.55414 4335.386784 3155.123176 3242.163449 2632.032322 4705.191821 3729.38815 4125.651428 0.885013728 0.804019695 0.844122244 1.050836907 0.764757574 0.785854914 0.637967692 1.140472457 0.903951343 1 12.01040622 -8.795519428 0.483789778 1.018273672 0.846110077 0.033620712 0.138948955 1.840525309 0.75794692 0.146925967 0.039186538 1.60E-09 8.795519428 -0.172163595 LGGAVPFAPPEVS(ph)PEQAK ddPTM_HeLa_Curcumin_4h_R1 2 LGGAVPFAPPEVSPEQAK 18 0 A0A096LNZ0;A0A096LP25;Q6ZSR9 A0A096LNZ0 AAK1 Uncharacterized protein FLJ45252 1 0 LGGAVPFAPPEVS(1)PEQAK;LGGAVPFAPPEVS(1)PEQAK ; 215.49 6.23E-17 330380000 15210.5 12379.5 12818.5 12565.4 12070.7 10480.4 5660.9 5607.4 15979.2 12445.9 TRUE FALSE FALSE 14006.57287 13449.52882 13293.56489 12513.4077 11926.76479 8306.646902 5819.729618 7317.070447 14226.32174 12878.3941 1.087602442 1.044348287 1.032237776 0.971659013 0.926106523 0.645006422 0.451898705 0.568166372 1.104665817 1 13.65266508 -5.257987937 1.788417227 1.038934496 0.499237917 0.95984621 0.045000393 0.047960003 0.290756397 0.00674525 0.022614649 5.52E-06 5.257987937 -0.53969658 LGGLLPPGGEGGPEATVVS(ph)DEDEAAEMEDEAVR ddPTM_HeLa_Curcumin_4h_R1 1 LGGLLPPGGEGGPEATVVSDEDEAAEMEDEAVR 33 0 P51178;P51178-2 P51178 PLCD1 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1" 1 0 LGGLLPPGGEGGPEAT(0.02)VVS(0.98)DEDEAAEMEDEAVR 63.768 0.00064833 0 548.31 366.1 458 506.33 544.74 532.93 564.25 477.66 680.72 523.03 TRUE FALSE FALSE 504.9106849 397.7440527 474.9738829 504.2349406 538.2443313 422.3943106 580.0813364 623.2963351 606.0467191 541.2052536 0.932937516 0.734922749 0.877622454 0.931688924 0.994529022 0.780469716 1.07183242 1.151681975 1.119809379 1 9.080032034 -4.537706201 24.52622019 0.933476517 1.131719638 0.35286465 0.104512705 118.3544744 195771.4172 0.01290363 0.0483201 2.90E-05 4.537706201 0.198243121 LGGLRPES(ph)PESLTS(ph)VSR ddPTM_HeLa_Curcumin_4h_R1 1 LGGLRPESPESLTSVSR 17 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 2 0 LGGLRPES(0.732)PES(0.268)LT(0.061)S(0.824)VS(0.115)R 126.43 0.001499 13760000 3257.6 2951.6 2960.3 3169.4 3233 3923.5 2897.3 707.49 3598.2 2749.1 TRUE FALSE FALSE 2999.757523 3206.723152 3070.011322 3156.285863 3194.448587 3109.721873 2978.59044 923.2004441 3203.486462 2844.63102 1.054533084 1.127289666 1.079230065 1.109558969 1.122974672 1.09318989 1.04709202 0.324541368 1.126151842 1 11.47402582 -4.261515128 7.7509644 1.054430189 0.317684464 0.956497953 0.048239353 0.015914927 10.33358315 0.007669767 0.061091334 5.48E-05 4.261515128 -0.736745725 LGGLRPES(ph)PESLTSVSR ddPTM_HeLa_Curcumin_4h_R1 4 LGGLRPESPESLTSVSR 17 1 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 0 LGGLRPES(0.899)PES(0.085)LT(0.017)SVSR;LGGLRPES(0.995)PES(0.004)LTSVSR;LGGLRPES(0.997)PES(0.002)LT(0.001)SVSR;LGGLRPES(0.983)PES(0.004)LT(0.013)SVSR ;;; 167.95 0.00014975 3527089000 11016 10231.1 10020.3 9449.1 10278 11285.8 9364.6 7083.7 10240 9339.4 TRUE FALSE FALSE 10144.07198 11115.4307 10391.66113 9410.002128 10155.44156 8944.997863 9627.345472 9243.487521 9116.697619 9663.943455 1.049682464 1.150196164 1.075302353 0.973722805 1.050858959 0.92560536 0.996212935 0.956492302 0.943372409 1 13.2383963 -5.272465691 24.86558023 1.035456665 0.963114472 0.27490976 0.055934325 640.7203054 1444896.639 0.007495725 0.016908593 5.34E-06 5.272465691 -0.072342193 LGGPEGPGS(ph)PLLAT ddPTM_HeLa_Curcumin_4h_R1 1 LGGPEGPGSPLLAT 14 0 Q9C086 Q9C086 INO80B INO80 complex subunit B 1 0 LGGPEGPGS(0.998)PLLAT(0.002) 101.56 0.004625 4586500 3657 2945.3 3169.7 3515.8 2967.2 3914.9 2808.5 2131.3 3769.6 3198.7 TRUE FALSE FALSE 3367.544591 3199.878608 3287.17187 3501.252551 2931.818078 3102.90561 2887.298951 2781.123559 3356.084311 3309.854587 1.01742977 0.966773169 0.993146914 1.057826699 0.885784557 0.937474904 0.872334079 0.840255511 1.013967298 1 11.69255212 -5.170303429 0.968252402 1.006944693 0.839245592 0.724549396 0.035805117 0.270619638 0.39831992 0.005388572 0.033889226 6.76E-06 5.170303429 -0.167699101 LGGSAVISLEGKPL ddPTM_HeLa_Curcumin_4h_R1 1 LGGSAVISLEGKPL 14 1 P23528;G3V1A4;E9PK25 P23528 CFL1 Cofilin-1 0 0 117.86 0.0069204 1825200 1280.2 1154.7 1275.9 1266.9 1330.9 1462.8 1072.9 1115 1271.9 1015.6 FALSE FALSE TRUE 1178.870819 1254.507123 1323.185976 1261.657903 1315.029887 1159.398791 1103.002686 1454.958367 1132.375752 1050.892024 1.121781108 1.193754538 1.259107449 1.200559024 1.251346338 1.10325206 1.049587075 1.384498439 1.077537678 1 10.03739873 -8.113866714 0.752015423 1.014602821 1.20037679 0.347116554 0.088679407 0.393681384 0.48681965 0.031379154 0.020706456 7.69E-09 8.113866714 0.185773969 LGGSLADSYLDEGFLLDKK ddPTM_HeLa_Curcumin_4h_R1 2 LGGSLADSYLDEGFLLDKK 19 1 F5GWF6;P78371;F8VQ14;P78371-2 F5GWF6 CCT2 T-complex protein 1 subunit beta 0 0 ; ; 197.1 3.63E-10 28280000 2568.2 1622.67 2297.94 2017.95 2003.32 2726 2156.43 1862.34 2287.5 1986.64 FALSE FALSE TRUE 2364.92426 1762.926364 2383.103678 2009.600258 1979.431717 2160.596872 2216.933622 2430.158893 2036.566973 2055.675592 1.150436513 0.857589773 1.159280038 0.977586281 0.962910551 1.051039804 1.078445271 1.182170427 0.990704458 1 11.00539689 -4.278579332 2.591613497 1.048214752 1.207001591 0.192204744 0.087771082 0.672245893 5.913696 0.01268107 0.227547797 5.27E-05 4.278579332 0.158786839 LGGSVLGQIPFLQNCEDEDS(ph)DEDDELDSVQHKK ddPTM_HeLa_Curcumin_4h_R1 1 LGGSVLGQIPFLQNCEDEDSDEDDELDSVQHKK 33 1 F5GYK2;Q9NRL3-2;Q9NRL3;Q9NRL3-3;R4GN16 F5GYK2 STRN4 Striatin-4 1 0 LGGSVLGQIPFLQNCEDEDS(0.988)DEDDELDS(0.012)VQHKK 53.088 0.0030566 20534000 1818.2 1247 1566.3 1840.7 1769.2 2583.8 1211.4 1251.5 2165.9 1589.5 TRUE FALSE FALSE 1674.287551 1354.785123 1624.348456 1833.083671 1748.103446 2047.890755 1245.388624 1633.076589 1928.306189 1644.735007 1.017967967 0.823710274 0.987604963 1.114516116 1.062848081 1.245118968 0.757197128 0.992911674 1.172411471 1 10.68363945 -4.726577463 24.99999953 1.018098422 0.875054692 0.210492941 0.123884978 214.5640819 153864.157 0.015077515 0.05640999 1.88E-05 4.726577463 -0.14304373 LGHDPYR ddPTM_HeLa_Curcumin_4h_R1 1 LGHDPYR 7 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6 P18583-10 SON Protein SON 0 0 111.04 0.012554 8396800 7021.8 5574.6 5802 6008.3 6359.2 8256.4 6559.6 3863.6 7093.3 5850.7 FALSE FALSE TRUE 6466.017121 6056.443584 6017.027224 5983.439247 6283.370693 6543.929571 6743.644722 5041.593854 6315.182737 6054.01139 1.068054998 1.000401749 0.993890965 0.988342912 1.037885509 1.080924556 1.113913451 0.832769139 1.043140214 1 12.56367567 LGHPEALSAGTGS(ph)PQPPSFTYAQQR ddPTM_HeLa_Curcumin_4h_R1 4 LGHPEALSAGTGSPQPPSFTYAQQR 25 0 Q15942;Q15942-2;H0Y2Y8;H7C3D3 Q15942 ZYX Zyxin 1 0 LGHPEALSAGT(0.005)GS(0.995)PQPPSFTYAQQR;LGHPEALSAGT(0.027)GS(0.973)PQPPSFTYAQQR;LGHPEALSAGT(0.001)GS(0.996)PQPPS(0.003)FTYAQQR;LGHPEALSAGT(0.002)GS(0.998)PQPPSFTYAQQR ;;; 157.73 2.24E-09 524630000 3574.51 3393.1 3303.52 3256.43 3791.75 4729.91 3491.41 2693.68 3878.87 2904.31 TRUE FALSE FALSE 3291.583762 3686.384445 3425.951357 3242.955756 3746.535858 3748.873349 3589.369568 3514.970632 3453.367665 3005.234556 1.09528348 1.226654484 1.139994664 1.079102378 1.246670031 1.247447838 1.194372519 1.16961607 1.149117515 1 11.55326188 -7.837773305 0.416674763 0.989788378 1.211021219 0.203682609 0.06764298 0.436053949 0.198441789 0.037612994 0.025563941 1.45E-08 7.837773305 0.221232842 LGHVVMGNNAVS(ph)PYQQVIEK ddPTM_HeLa_Curcumin_4h_R1 2 LGHVVMGNNAVSPYQQVIEK 20 0 P60228;H0YAW4;E5RGA2 P60228 EIF3E Eukaryotic translation initiation factor 3 subunit E 1 0 LGHVVMGNNAVS(0.999)PY(0.001)QQVIEK;LGHVVMGNNAVS(0.997)PY(0.003)QQVIEK ; 146.3 3.22E-05 72499000 3581.9 3097.1 3361.5 3902.5 3354.9 4594.7 3262.9 2472.1 3949.8 3718.3 TRUE FALSE FALSE 3298.388835 3364.799524 3486.080147 3886.352489 3314.895009 3641.707427 3354.448192 3225.83191 3516.516822 3847.510648 0.857278676 0.874539366 0.906061208 1.010095317 0.861568768 0.946510032 0.871848969 0.838420528 0.913971953 1 11.9097096 -9.438666769 1.154088702 1.000352029 0.895167677 0.095088766 0.054152331 0.404625951 0.958892266 0.034109921 0.008411025 3.64E-10 9.438666769 -0.105184352 LGIAVIHGEAQDAES(ph)DLVDGRHSPPMVR ddPTM_HeLa_Curcumin_4h_R1 1 LGIAVIHGEAQDAESDLVDGRHSPPMVR 28 1 C9K0K7;I3L0S1;E7EPA1;O60256-4;O60256-3;O60256-2;O60256 C9K0K7 PRPSAP2 Phosphoribosyl pyrophosphate synthase-associated protein 2 1 0 LGIAVIHGEAQDAES(0.623)DLVDGRHS(0.377)PPMVR 63.165 0.00036532 31923000 1368 1396.4 1244.7 1340.8 1367.9 1607.3 1284 1120.3 1744 1481.9 TRUE FALSE FALSE 1259.721356 1517.098594 1290.829677 1335.252125 1351.588686 1273.927862 1320.025584 1461.874313 1552.687563 1533.395915 0.821523877 0.989371746 0.841811084 0.870781063 0.881434907 0.830788611 0.860851116 0.953357381 1.012580996 1 10.58251453 -9.495727721 1.171180471 1.001815373 0.874395427 0.484699148 0.050852527 0.351905924 0.843592302 0.037168604 0.008512523 3.19E-10 9.495727721 -0.127419946 LGIAVIHGEAQDAESDLVDGRHS(ph)PPMVR ddPTM_HeLa_Curcumin_4h_R1 1 LGIAVIHGEAQDAESDLVDGRHSPPMVR 28 1 C9K0K7;I3L0S1;E7EPA1;O60256-4;O60256-3;O60256-2;O60256 C9K0K7 PRPSAP2 Phosphoribosyl pyrophosphate synthase-associated protein 2 1 0 LGIAVIHGEAQDAES(0.283)DLVDGRHS(0.717)PPMVR 40.533 0.015473 171890000 2153.5 1959.6 1927 1936.1 1903 2978.4 1709 1515.3 2361.2 1995.2 TRUE FALSE FALSE 1983.048203 2128.979092 1998.416315 1928.088931 1880.307968 2360.646267 1756.94994 1977.307994 2102.182267 2064.533051 0.9605311 1.031215795 0.967974968 0.933910421 0.910766707 1.143428663 0.851015652 0.957750709 1.018236189 1 11.0115998 -6.536334165 24.56659573 0.985295187 0.959885633 0.054714644 0.072564426 654.3450252 1194684.214 0.010745184 0.01520049 2.91E-07 6.536334165 -0.025409554 LGIHEDSQNR ddPTM_HeLa_Curcumin_4h_R1 5 LGIHEDSQNR 10 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 ;;;; ;;;; 174.86 1.91E-05 106808000 28968.5 23659.1 23500.1 23572.8 28264.7 38616.8 25975.8 24902.3 31321.6 24145.1 FALSE FALSE TRUE 26675.61266 25704.08718 24371.03438 23475.262 27927.66191 30607.24038 26704.61104 32494.89663 27885.69884 24984.14043 1.067701838 1.028816151 0.97546019 0.93960655 1.1178156 1.225066777 1.06886251 1.300620957 1.116136011 1 14.60872496 -5.546373605 6.734358825 1.022018662 1.183347264 0.562828273 0.070044634 0.085222526 14.47889121 0.009004277 0.018398775 2.84E-06 5.546373605 0.161328602 LGIHEDSTNR ddPTM_HeLa_Curcumin_4h_R1 6 LGIHEDSTNR 10 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 0 ;;;;; ;;;;; 245.5 1.28E-23 206992000 58397.2 49965.8 45963.8 47583.6 61527.8 75020.9 51439.5 51107.4 60626.8 48660.8 FALSE FALSE TRUE 53775 54284.62111 47667.25886 47386.71167 60794.12117 59460.71968 52882.75393 66689.81099 53976.19172 50351.75918 1.067986519 1.078107736 0.946685074 0.941113328 1.207388226 1.1809065 1.050266263 1.324478272 1.071982243 1 15.61975456 -1 0.470609215 1.026360105 7.717851467 0.485707993 0.081849465 54.34143934 0.560526465 0.016870509 356.4828975 0.1 1 6.691491362 LGIHEDSTNRR ddPTM_HeLa_Curcumin_4h_R1 1 LGIHEDSTNRR 11 1 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 0 56.013 0.01697 6468800 5979.6 5376.1 5191.6 5205.8 6355.2 7813.5 5331.4 5280.2 6877.9 5737.4 FALSE FALSE TRUE 5506.30835 5840.786129 5384.005263 5184.259779 6279.418391 6192.892024 5480.984735 6890.108673 6123.411578 5936.774223 0.927491621 0.983831608 0.906890689 0.873245231 1.057715546 1.043140903 0.92322607 1.16058122 1.031437503 1 12.53546353 -4.253596291 24.31009418 0.965397055 1.160581362 0.470789821 0.05966198 424.1254969 1314553.452 0.007997856 0.113954945 5.58E-05 4.253596291 0.195184307 LGIYDADGDGDFDVDDAK ddPTM_HeLa_Curcumin_4h_R1 1 LGIYDADGDGDFDVDDAK 18 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797;E5RHK2;G3XAN5;E5RG29;Q12797-4;Q12797-3;Q12797-9;Q12797-5;Q12797-8;Q12797-10 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 0 0 113.29 0.00046083 3501000 1489.3 1419.3 1534.3 2229.2 1674.5 2229.5 1018.9 1003.4 2132.6 1391.1 FALSE FALSE TRUE 1371.420333 1541.977968 1591.162508 2219.976161 1654.532681 1767.076568 1047.487592 1309.332041 1898.659116 1439.440621 0.952745332 1.071234162 1.105403366 1.54224921 1.149427532 1.227613381 0.727704621 0.909611707 1.31902566 1 10.49129256 -3.009414647 13.78607761 1.033950083 1.071858441 0 0.226708052 0 0 0.028819243 0 0.000978555 3.009414647 0.037908358 LGK(ac)ELQQK ddPTM_HeLa_Curcumin_4h_R1 1 LGKELQQK 8 1 Q14DU5;E9PF63;O75116 Q14DU5 ROCK2 Rho-associated protein kinase 2 0 1 LGK(1)ELQQK 106.36 0.0083753 3868500 2845.5 1617.7 2550.9 1834.2 2445.6 2841.7 2345.4 2229.9 2263.7 2652.2 FALSE TRUE FALSE 2620.275672 1757.52678 2645.438598 1826.610566 2416.437817 2252.299387 2411.205612 2909.786245 2015.377773 2744.363753 0.95478439 0.640413203 0.963953337 0.665586173 0.880509304 0.82070002 0.878602776 1.060277174 0.734369768 1 11.422256 -7.49455493 23.13028275 0.980052176 0.840524111 0 0.140845091 138.7665949 113324.2597 0.019121789 0.020767641 3.20E-08 7.49455493 -0.139528065 LGK(ac)TIVITK ddPTM_HeLa_Curcumin_4h_R1 2 LGKTIVITK 9 1 R4GNG8;Q96NC0 R4GNG8 ZMAT2 Zinc finger matrin-type protein 2 0 1 ; LGK(1)TIVITK;LGK(1)TIVITK 106.4 0.00033745 0 4059 4138.9 3862.7 3630.2 3023.7 4700.4 3302.5 3743.8 3806.8 3796.1 FALSE TRUE FALSE 3737.725867 4496.648073 4005.85506 3615.179194 2987.644352 3725.484056 3395.159262 4885.267386 3389.203564 3928.014192 0.9515561 1.144763703 1.01981685 0.920357977 0.760599175 0.948439561 0.864344958 1.243699016 0.862828747 1 11.93958443 -6.253793866 23.95622613 0.994693526 0.932539209 0.026375573 0.131857885 851.9886976 2669590.919 0.018312634 0.029972816 5.57E-07 6.253793866 -0.062154317 LGLAVIHGEAQCT(ph)ELDMDDGRHSPPMVK ddPTM_HeLa_Curcumin_4h_R1 1 LGLAVIHGEAQCTELDMDDGRHSPPMVK 28 1 C9JUN4;C9J168;B4DP31;Q14558;Q14558-2 C9JUN4 PRPSAP1 Phosphoribosyl pyrophosphate synthase-associated protein 1 1 0 LGLAVIHGEAQCT(0.804)ELDMDDGRHS(0.196)PPMVK 55.228 0.0015601 36187000 1460.9 1171.9 1324 1470.5 1287.2 1585.6 980.22 911.36 1647.7 1343 TRUE FALSE FALSE 1345.268223 1273.193814 1373.068605 1464.415461 1271.850981 1256.728687 1007.722335 1189.229469 1466.951432 1389.66915 0.968049282 0.916184844 0.988054318 1.053787127 0.915218547 0.904336609 0.725152699 0.855764459 1.055612001 1 10.44052573 -5.113080185 2.152581314 0.982359493 0.792291718 0.667988219 0.054263043 0.121262908 1.077295642 0.006668029 0.023101296 7.71E-06 5.113080185 -0.190067774 LGLAVIHGEAQCTELDMDDGRHS(ph)PPMVK ddPTM_HeLa_Curcumin_4h_R1 4 LGLAVIHGEAQCTELDMDDGRHSPPMVK 28 1 C9JUN4;C9J168;B4DP31;Q14558;Q14558-2 C9JUN4 PRPSAP1 Phosphoribosyl pyrophosphate synthase-associated protein 1 1 0 LGLAVIHGEAQCT(0.421)ELDMDDGRHS(0.579)PPMVK;LGLAVIHGEAQCT(0.348)ELDMDDGRHS(0.652)PPMVK;LGLAVIHGEAQCT(0.005)ELDMDDGRHS(0.995)PPMVK;LGLAVIHGEAQCT(0.019)ELDMDDGRHS(0.981)PPMVK ;;; 58.952 0.00085039 112697000 4566.9 3657.71 3633.13 3996.18 4044.41 4613.97 3075.14 2830.37 4712.68 4069.65 TRUE FALSE FALSE 4205.425046 3973.866154 3767.776994 3979.644866 3996.183052 3656.980612 3161.420152 3693.336784 4195.710795 4211.070035 0.998659488 0.943671352 0.894731496 0.945043619 0.948970931 0.868420753 0.750740341 0.877054229 0.996352651 1 12.03997115 -5.354485389 0.43977439 1.004081669 0.764934073 0.654530824 0.04326377 0.890844861 0.213714743 0.011983011 0.095600478 4.42E-06 5.354485389 -0.239147595 LGLDYEER ddPTM_HeLa_Curcumin_4h_R1 1 LGLDYEER 8 0 Q99623-2;Q99623;F5H3X6;F5GWA7;F5GY37;J3KPX7 Q99623-2 PHB2 Prohibitin-2 0 0 97.798 0.015431 2178300 2119.5 1287 1251.6 1758 1752 2439 1812.9 1786.4 2049.6 1250.1 FALSE FALSE TRUE 1951.739339 1398.242545 1297.985397 1750.725862 1731.108544 1933.123907 1863.765095 2331.065136 1824.764008 1293.540882 1.508834677 1.080941905 1.003435929 1.353436823 1.338271228 1.494443611 1.440824268 1.802080761 1.410673627 1 10.33710994 -1 0.035701181 2.54E-10 3.4932113 0.260753215 0.206547362 782.6049988 2.15659756 62.27785484 176.3265165 0.1 1 3.493211299 LGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSR ddPTM_HeLa_Curcumin_4h_R1 8 LGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSR 34 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 ;;;;;;; ;;;;;;; 232.93 2.12E-51 326772000 25507.77 22430.7 23399.99 22474.68 27220.18 25687.27 21030.99 21299.09 19276.2 18598.1 FALSE FALSE TRUE 23488.80309 24369.50976 24267.21421 22381.68573 26895.59713 20359.44065 21621.06298 27793.08449 17161.64909 19244.38259 1.220553737 1.266318088 1.261002482 1.163024359 1.39758171 1.057942002 1.123499955 1.444218039 0.89177447 1 14.23214977 -9.009423642 0.660817199 0.986078687 1.238567498 0.493126969 0.116245389 0.658426965 0.492476796 0.091658901 0.023518573 9.79E-10 9.009423642 0.252488811 LGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD ddPTM_HeLa_Curcumin_4h_R1 7 LGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD 39 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 ;;;;;; ;;;;;; 137.71 6.34E-25 45972900 24983.7 20744.58 19723.5 22879.23 19661.4 29429.5 21623.63 22590.57 26331.8 21975.8 FALSE FALSE TRUE 23006.21378 22537.64906 20454.47026 22784.56181 19426.95065 23325.48996 22230.33086 29478.3308 23443.26742 22739.45741 1.011730991 0.99112519 0.899514438 1.00198353 0.854327801 1.025771615 0.977610435 1.296351547 1.030951047 1 14.47291021 -4.260345148 24.75775788 0.987247988 1.296351661 0.752698783 0.054631551 29.72771349 672506.9474 0.007248902 0.059355179 5.49E-05 4.260345148 0.309103673 LGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASR ddPTM_HeLa_Curcumin_4h_R1 3 LGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASR 34 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 0 ;; ;; 177.79 3.70E-26 409847000 8261.1 7064 8283.6 7969 8633.4 9272.4 7458.2 7585.8 7833.6 7013.3 FALSE FALSE TRUE 7607.225218 7674.580683 8590.597503 7936.02639 8530.452344 7349.199719 7667.457019 9898.675499 6974.273679 7257.011653 1.048258647 1.05754008 1.183765152 1.093566714 1.175477283 1.01270331 1.056558455 1.364015379 0.961039339 1 12.82515987 -1 0.166562092 0.985546661 1.873566243 0.419335947 0.085377878 49.29702746 0.511420057 0.1313006 10.9061969 0.1 1 0.888019582 LGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRMEEVD ddPTM_HeLa_Curcumin_4h_R1 3 LGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRMEEVD 39 1 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 0 ;; ;; 93.566 3.76E-14 17772700 10593.9 6820.6 7137.3 8832 6687.5 11200 8100.5 8616.7 12732.3 9762 FALSE FALSE TRUE 9755.381636 7410.142272 7401.814617 8795.455524 6607.75593 8876.99375 8327.778229 11243.89216 11335.59854 10101.22877 0.965761875 0.733588204 0.732763784 0.870731247 0.654153676 0.878803356 0.824432197 1.113121227 1.122199962 1 13.30224318 -7.384061647 6.4450675 0.984955355 0.822699699 0.336349729 0.123854513 0.217813624 10.63693526 0.01924384 0.021918126 4.13E-08 7.384061647 -0.162255656 LGLPLLTDCAQPS(ph)RPHGSPSR ddPTM_HeLa_Curcumin_4h_R1 1 LGLPLLTDCAQPSRPHGSPSR 21 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 1 0 LGLPLLTDCAQPS(0.44)RPHGS(0.44)PS(0.121)R 69.081 0.001294 20552000 3585.7 2960.6 2714.5 2683.7 3073.4 4536.7 2755 1781.9 3869 3301.8 TRUE FALSE FALSE 3301.888061 3216.501072 2815.101758 2672.59556 3036.751712 3595.737281 2832.297885 2325.193107 3444.58038 3416.537304 0.966442853 0.941450593 0.823963419 0.782252709 0.888839033 1.05245076 0.828996622 0.680570092 1.00820804 1 11.73831916 -6.936562777 3.563928476 0.983402828 0.851303007 0.366879154 0.088594368 0.214709116 5.570120992 0.015025033 0.019846458 1.16E-07 6.936562777 -0.132099821 LGLPLLTDCAQPSRPHGSPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 LGLPLLTDCAQPSRPHGSPSR 21 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 1 0 LGLPLLTDCAQPS(0.001)RPHGS(0.281)PS(0.718)R 76.351 0.00077069 49261000 796.33 608.3 773.12 634.26 683.8 850.07 401.27 415.02 1016.1 654.51 TRUE FALSE FALSE 733.2996402 660.8787415 801.7725073 631.6356002 675.6461316 673.7558997 412.5285562 541.5576875 904.6363722 677.2541738 1.082753962 0.975820847 1.18385761 0.932641872 0.997625644 0.994834622 0.609119253 0.799637283 1.335741302 1 9.403553569 -4.83327712 6.310623835 1.03382494 0.705815989 0.569078255 0.122930376 0.063772149 4.286770692 0.010200766 0.031577582 1.47E-05 4.83327712 -0.328008951 LGLSTLGELK ddPTM_HeLa_Curcumin_4h_R1 1 LGLSTLGELK 10 0 O43399;O43399-5;O43399-7;A0A087WYR3;O43399-2;O43399-4;O43399-3;A0A087WZ51;O43399-6 O43399 TPD52L2 Tumor protein D54 0 0 115.7 1.14E-05 0 84.633 159.84 0 0 0 0 178 164.89 72.794 157.07 FALSE FALSE TRUE 77.93420875 173.6558574 0 0 0 0 182.9942009 215.1642019 64.80868032 162.5281708 0.479512003 1.068466202 0 0 0 0 1.125922971 1.323857894 0.398753521 1 7.34454599 -9.023895771 0.637361749 1.033821341 0.457544184 0 0.522690176 1.557897876 1.063660494 0.488743342 0.119599121 9.46E-10 9.023895771 -0.576277156 LGLVS(ph)PESMDNYSHFHELR ddPTM_HeLa_Curcumin_4h_R1 2 LGLVSPESMDNYSHFHELR 19 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3 RAI14 Ankycorbin 1 0 LGLVS(0.988)PES(0.011)MDNYSHFHELR;LGLVS(0.915)PES(0.081)MDNYS(0.003)HFHELR ; 82.865 0.002496 10794200 3131.1 2680.3 2676.1 2437.8 3681.1 7876.3 4443 4255 4052.9 2835.8 TRUE FALSE FALSE 2883.270131 2911.973189 2775.27862 2427.71303 3637.205287 6242.666596 4567.658622 5552.329912 3608.30701 2934.343839 0.982594505 0.992376268 0.945791895 0.82734443 1.239529342 2.127448908 1.556620108 1.892187902 1.229681049 1 11.51882222 -5.446299535 4.798565091 0.978763048 1.822490216 0.850270795 0.161399666 0.04575663 1.915948574 0.017986982 0.040773805 3.58E-06 5.446299535 0.843727168 LGMLS(ph)PEGTCK ddPTM_HeLa_Curcumin_4h_R1 1 LGMLSPEGTCK 11 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 1 0 LGMLS(1)PEGTCK 107.11 0.0077783 44435000 2977.7 2307.9 2618.3 3350 2794 3014 2307 1898.1 3277.6 2839.7 TRUE FALSE FALSE 2742.011903 2507.384592 2715.336501 3336.138588 2760.683375 2388.862425 2371.728211 2476.821952 2918.05548 2938.379364 0.933171508 0.853322285 0.924093238 1.135366872 0.939525852 0.812986388 0.80715521 0.842921096 0.993083302 1 11.52080495 -5.312506489 5.056863506 0.96723491 0.819276775 0.494210188 0.068619689 0.136369297 7.910006583 0.010262964 0.023878941 4.87E-06 5.312506489 -0.147958136 LGNDFHTNK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 LGNDFHTNKR 10 1 H0YN88;A0A075B716;H3BNC9;P08708;H0YN73;A0A0J9YYC4 H0YN88 RPS17 40S ribosomal protein S17 0 1 ; LGNDFHTNK(1)R;LGNDFHTNK(1)R 67.214 0.019111 13922100 8463.8 8905.9 7528.9 6447.3 12850.9 18163.1 12788.7 10187.4 16058.1 7698.5 FALSE TRUE FALSE 7793.881299 9675.686312 7807.927657 6420.622781 12697.66141 14395.86832 13147.5165 13293.49136 14296.56661 7966.022302 0.978390595 1.214619536 0.980153879 0.806001105 1.593977638 1.807158927 1.650449372 1.668774058 1.794693269 1 12.9596438 -5.678851587 5.825768821 0.996491856 1.699546743 0.459042899 0.272213434 0.039712136 2.172474576 0.014477631 0.029135191 2.09E-06 5.678851587 0.703054887 LGNDFHTNKR ddPTM_HeLa_Curcumin_4h_R1 1 LGNDFHTNKR 10 1 H0YN88;A0A075B716;H3BNC9;P08708;H0YN73;A0A0J9YYC4 H0YN88 RPS17 40S ribosomal protein S17 0 0 36.424 0.018397 5197300 6812.3 4519.9 4672.9 5303.2 6098.7 6894.9 4836 5289.2 5856.2 4731.1 FALSE FALSE TRUE 6273.099267 4910.580016 4846.081785 5281.256764 6025.976986 5464.820018 4971.685145 6901.852732 5213.789511 4895.505373 1.281399731 1.003079282 0.989904293 1.078797052 1.230920309 1.116293335 1.015561166 1.409834574 1.065015584 1 12.25724208 -4.249149996 24.13892289 1.11313093 1.409834874 0.479156316 0.097625447 1066.010189 2093805.829 0.016906219 0.373387073 5.63E-05 4.249149996 0.296703944 LGNSGAS(ph)PSSAGK ddPTM_HeLa_Curcumin_4h_R1 2 LGNSGASPSSAGK 13 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 0 LGNS(0.164)GAS(0.82)PS(0.015)S(0.001)AGK;LGNS(0.001)GAS(0.784)PS(0.214)SAGK ; 128.73 0.0017374 15683200 4670.6 2786.19 4063.2 4951.8 4316.3 4828.9 3847.2 1717 5223.9 3979.8 TRUE FALSE FALSE 4300.917082 3027.015849 4213.785766 4931.310764 4264.830942 3827.331707 3955.142078 2240.505396 4650.85124 4118.097754 1.04439412 0.735051966 1.023235974 1.197472974 1.035631303 0.929393117 0.960429381 0.544063189 1.129368829 1 12.00776236 -3.963368187 1.694878737 1.011291684 6.51E-09 0.591723165 0.115732568 1.207624384 1.756005224 0.01564883 2.527784874 0.000108801 3.963368187 -1.011291677 EGSTQQLQTTS(ph)PKPLVQQPILPVVK ddPTM_HeLa_Curcumin_4h_R1 1 EGSTQQLQTTSPKPLVQQPILPVVK 25 1 A0A087X0H9;Q5T8P6-5;Q5T8P6-4;Q5T8P6-3 A0A087X0H9 RBM26 RNA-binding protein 26 1 0 EGS(0.001)T(0.001)QQLQT(0.029)T(0.096)S(0.872)PKPLVQQPILPVVK 57.768 0.0028026 47967000 1047.8 871.01 910.28 711.41 826.37 1088.2 1127.6 1931.2 940.91 869.7 TRUE FALSE FALSE 964.8655244 946.2962233 944.0157776 708.4663739 816.5160775 862.4950535 1159.237421 2520.01399 837.694527 899.9220103 1.072165714 1.051531369 1.048997321 0.78725308 0.90731871 0.958410889 1.288153204 2.800258201 0.93085236 1 9.813656169 -4.256925113 2.971394686 1.007228719 3.109835092 0.97504191 0.08730818 0.045278985 0.570259529 0.013179066 0.226715439 5.53E-05 4.256925113 2.102606373 up LGPGRPLPTFPTS(ph)ECTSDVEPDTR ddPTM_HeLa_Curcumin_4h_R1 1 LGPGRPLPTFPTSECTSDVEPDTR 24 1 Q8TDD1-2;Q8TDD1;H0YHZ9 Q8TDD1-2 DDX54 ATP-dependent RNA helicase DDX54 1 0 LGPGRPLPTFPT(0.08)S(0.307)ECT(0.307)S(0.307)DVEPDTR 79.373 0.00011698 45255000 870.99 818.6 750.43 871.33 830.82 729.11 491.46 521.91 876.22 886.22 TRUE FALSE FALSE 802.0502224 889.3561364 778.2415959 867.7246673 820.9130141 577.8843672 505.2490449 681.0379564 780.1008582 917.016079 0.87463049 0.969837015 0.848667339 0.94624804 0.89520024 0.6301791 0.550970759 0.74266741 0.850694853 1 9.84080322 -5.296405397 4.407425942 0.933767435 0.629934038 0.779994892 0.06539668 0.062898407 2.888940226 0.009444899 0.022711757 5.05E-06 5.296405397 -0.303833396 LGPGRPLPTFPTSECTS(ph)DVEPDTR ddPTM_HeLa_Curcumin_4h_R1 1 LGPGRPLPTFPTSECTSDVEPDTR 24 1 Q8TDD1-2;Q8TDD1;H0YHZ9 Q8TDD1-2 DDX54 ATP-dependent RNA helicase DDX54 1 0 LGPGRPLPTFPT(0.003)S(0.06)ECT(0.204)S(0.731)DVEPDT(0.001)R 60.797 0.0023536 47486000 789.14 592.59 690.36 940.04 465.29 548.02 681.38 547.97 774.81 777.17 TRUE FALSE FALSE 726.6787363 643.8108391 715.9453489 936.1503636 459.7417206 434.3544745 700.497689 715.0435305 689.8152815 804.1765997 0.90363079 0.800583901 0.890283738 1.164110425 0.571692487 0.540123245 0.87107445 0.889162319 0.857790791 1 9.651368546 -5.750426908 24.99999558 0.948357426 0.716239687 0.372828077 0.137991231 172.70175 392056.7111 0.020226951 0.040147301 1.78E-06 5.750426908 -0.23211774 LGQEATVGK ddPTM_HeLa_Curcumin_4h_R1 2 LGQEATVGK 9 0 P53396;P53396-2;K7ESG8 P53396 ACLY ATP-citrate synthase 0 0 ; ; 128.27 0.00072278 11442000 5388.2 4377.9 4786.7 4925.1 5124.3 5814.8 4244.2 4532.9 5622.3 5036.4 FALSE FALSE TRUE 4961.718284 4756.306168 4964.099313 4904.721241 5063.196069 4608.744934 4363.280829 5914.960343 5005.547756 5211.414525 0.952086667 0.912670858 0.952543554 0.941149705 0.971558882 0.884355852 0.837254609 1.135000932 0.96049695 1 12.3474593 -8.710450404 0.759510197 0.99849269 0.94186252 0.013211866 0.074058938 1.235147549 1.404758223 0.037026449 0.014787625 1.95E-09 8.710450404 -0.05663017 LGQSDPAPLQHQMDIYQK ddPTM_HeLa_Curcumin_4h_R1 1 LGQSDPAPLQHQMDIYQK 18 0 P29401;P29401-2;A0A0B4J1R6;E9PFF2 P29401 TKT Transketolase 0 0 99.392 0.0060275 42099000 1521.5 1145 1411 1378 1480.8 2406.1 1929.1 1588.5 1555 1155.2 FALSE FALSE TRUE 1401.07167 1243.968698 1463.292901 1372.298201 1463.142427 1907.047738 1983.225354 2072.826337 1384.42039 1195.343114 1.17210837 1.040679185 1.224161401 1.148037066 1.224035517 1.595397769 1.659126431 1.734084811 1.158178245 1 10.22320908 -5.257943227 1.365857165 1.089519462 1.737962506 0.929295282 0.066889302 0.092793605 0.31582242 0.012058898 0.049077047 5.52E-06 5.257943227 0.648443045 LGRET(ph)EEQDSDSAEQGDPAGEGK ddPTM_HeLa_Curcumin_4h_R1 1 LGRETEEQDSDSAEQGDPAGEGK 23 1 H0Y626;O95361 H0Y626 TRIM16 Tripartite motif-containing protein 16 1 0 LGRET(0.724)EEQDS(0.138)DS(0.138)AEQGDPAGEGK 116.27 3.67E-06 19826000 3833.9 2854.7 2801.6 2747.6 2533.1 3944.3 2738.3 3037.6 3996.1 3886.3 TRUE FALSE FALSE 3530.442769 3101.447548 2905.429761 2736.231159 2502.894437 3126.207719 2815.129328 3963.750257 3557.737828 4021.348636 0.877925067 0.771245626 0.722501336 0.680426247 0.622401752 0.777402807 0.700046075 0.98567685 0.884712605 1 11.9734637 -7.633023048 1.03746066 0.968621012 0.737254028 0.386507255 0.096199818 0.252959173 0.562617514 0.021931821 0.021569906 2.33E-08 7.633023048 -0.231366985 LGRGS(ph)VSDCSDGTSELEEPLGEDPR ddPTM_HeLa_Curcumin_4h_R1 2 LGRGSVSDCSDGTSELEEPLGEDPR 25 1 P50548;P50548-2 P50548 ERF ETS domain-containing transcription factor ERF 1 0 LGRGS(0.695)VS(0.209)DCS(0.083)DGT(0.009)S(0.004)ELEEPLGEDPR;LGRGS(0.736)VS(0.258)DCS(0.006)DGTSELEEPLGEDPR ; 109.2 9.60E-08 27922000 2484.61 2033.61 2449.77 2247.45 2532.26 3066.9 2578.6 3433.1 2630.64 2437.13 TRUE FALSE FALSE 2287.950497 2209.386187 2540.560631 2238.150647 2502.064453 2430.790369 2650.948576 4479.836386 2342.065374 2521.820086 0.907261588 0.876107776 1.007431357 0.887514006 0.992166121 0.963903168 1.051204482 1.776429814 0.928720247 1 11.30024964 -4.247595256 3.138396516 0.951861784 1.915386022 0.968790856 0.044457589 0.049122374 0.716999641 0.006834306 0.117994653 5.65E-05 4.247595256 0.963524238 LGS(ph)ALLIR ddPTM_HeLa_Curcumin_4h_R1 2 LGSALLIR 8 0 Q14993 Q14993 COL19A1 Collagen alpha-1(XIX) chain 1 0 LGS(1)ALLIR;LGS(1)ALLIR ; 111.06 0.010985 37799000 4905.2 4123.6 4386.1 4875.4 4547.1 6540.3 5129.3 4202.9 5035.1 5052.5 TRUE FALSE FALSE 4516.948244 4480.02561 4548.652724 4855.226887 4492.878802 5183.768056 5273.214353 5484.344862 4482.762127 5228.073999 0.863979401 0.856917023 0.870043677 0.928683658 0.859375518 0.991525379 1.008634223 1.049018217 0.857440451 1 12.35206385 -5.055314657 5.134807097 0.918292136 1.023238272 0.544505951 0.048930422 0.173779846 9.854260204 0.00892754 0.024185597 8.80E-06 5.055314657 0.104946137 LGS(ph)FGSITR ddPTM_HeLa_Curcumin_4h_R1 6 LGSFGSITR 9 0 Q14315-2;Q14315 Q14315-2 FLNC Filamin-C 1 0 LGS(0.988)FGS(0.012)ITR;LGS(0.996)FGS(0.004)ITR;LGS(0.864)FGS(0.136)IT(0.001)R;LGS(1)FGSITR;LGS(0.997)FGS(0.003)ITR;LGS(0.95)FGS(0.034)IT(0.016)R ;;;;; 164.66 0.0004596 4657067700 15152.3 14655.17 14274.84 14765.06 14017.83 20134.9 19828.66 5910.29 17762.1 14093.92 TRUE FALSE FALSE 13952.97947 15921.89759 14803.87813 14703.96609 13850.67653 15958.69477 20384.99883 7712.310213 15813.64207 14583.68267 0.956752816 1.091761111 1.015098755 1.008247809 0.949737926 1.094284286 1.397795008 0.528831461 1.084338053 1 13.83206745 -7.306261358 24.58364911 0.979577722 1.02778601 0 0.203205347 1752.082402 960964.4708 0.03107176 0.035531946 4.94E-08 7.306261358 0.048208287 LGS(ph)LSAR ddPTM_HeLa_Curcumin_4h_R1 3 LGSLSAR 7 0 H0Y2V6;Q5SW79;Q5SW79-3;Q5SW79-2;H0Y4T4;Q00G26 H0Y2V6 CEP170;PLIN5 Centrosomal protein of 170 kDa;Perilipin-5 1 0 LGS(0.819)LS(0.181)AR;LGS(0.997)LS(0.003)AR;LGS(0.998)LS(0.002)AR ;; 122.19 0.010904 81370000 10079 7488.9 10527.7 10168.4 10447.4 13023.9 15099.5 13484.3 10413.2 9780.3 TRUE FALSE FALSE 9281.236515 8136.207146 10917.86582 10126.32586 10322.82158 10322.59633 15523.15133 17595.601 9270.898013 10120.1647 0.917103307 0.803959954 1.078822939 1.0006088 1.020025058 1.0200028 1.533883271 1.738667455 0.916081733 1 13.30494515 -4.689845489 2.638783725 0.963391368 1.725260113 0.934728944 0.071539764 0.048560659 0.643785404 0.010421739 0.054144731 2.04E-05 4.689845489 0.761868746 LGS(ph)PDTVSPR ddPTM_HeLa_Curcumin_4h_R1 2 LGSPDTVSPR 10 0 H0Y9Y2 H0Y9Y2 BOD1L1 1 0 LGS(0.858)PDT(0.133)VS(0.009)PR;LGS(0.86)PDT(0.14)VSPR ; 125.23 0.0036615 13399900 4265.8 4007 3675.1 3668.5 3597.5 4200.6 2461.53 2334.18 4475.4 3987.6 TRUE FALSE FALSE 3928.157429 4353.347225 3811.302439 3653.320719 3554.602162 3329.348209 2530.593907 3045.860737 3984.459817 4126.168803 0.95201084 1.055057956 0.923690382 0.885402632 0.86147764 0.806886089 0.613303534 0.738181321 0.965656038 1 12.01058713 -5.361658955 0.891473283 0.981957651 0.655985118 0.840985241 0.049875132 0.193691709 0.253591848 0.008001808 0.042417492 4.35E-06 5.361658955 -0.325972533 LGS(ph)PDYGNSALLSLPGYRPTTR ddPTM_HeLa_Curcumin_4h_R1 2 LGSPDYGNSALLSLPGYRPTTR 22 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 LGS(0.493)PDY(0.051)GNS(0.456)ALLSLPGYRPTTR;LGS(0.709)PDY(0.208)GNS(0.083)ALLSLPGYRPTTR ; 97.068 7.78E-05 292320000 1455.7 1112.88 1250.77 1348.54 1266.69 2049.66 1651.41 1209.76 1625.67 1234.51 TRUE FALSE FALSE 1340.479809 1209.072388 1297.124636 1342.960099 1251.585549 1624.537412 1697.74412 1578.610255 1447.338068 1277.409131 1.049373906 0.946503637 1.015433979 1.051315563 0.979784408 1.271744011 1.329052752 1.235790646 1.133026243 1 10.31900495 -5.254774444 24.3461839 1.016944158 1.283881537 0.833879726 0.051808036 70.79739286 258612.6492 0.00518674 0.012886736 5.56E-06 5.254774444 0.26693738 EGSVLDILKS(ph)PGFASPK ddPTM_HeLa_Curcumin_4h_R1 2 EGSVLDILKSPGFASPK 17 1 P49790-3;P49790 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 0 EGSVLDILKS(0.865)PGFAS(0.135)PK;EGSVLDILKS(0.984)PGFAS(0.015)PK ; 76.492 0.0054036 173853000 7341.9 5795.8 6362.4 6683.6 5600.5 8488.4 8601.6 18983.2 8221.4 7310.4 TRUE FALSE FALSE 6760.780868 6296.763126 6598.196141 6655.945034 5533.717695 6727.810156 8842.937746 24771.09029 7319.532989 7564.435856 0.893758768 0.832416752 0.872265463 0.879899726 0.731544004 0.88940012 1.169014837 3.274677817 0.967624437 1 12.88501678 -4.256810802 3.508273408 0.912734126 3.572474667 0.989401298 0.073736883 0.02489193 0.526193861 0.012500714 0.175698529 5.54E-05 4.256810802 2.659740541 up S(ph)PSGPPAMDLEGPR ddPTM_HeLa_Curcumin_4h_R1 2 SPSGPPAMDLEGPR 14 0 O96018 O96018 APBA3 Amyloid beta A4 precursor protein-binding family A member 3 1 0 S(0.975)PS(0.025)GPPAMDLEGPR;S(0.997)PS(0.003)GPPAMDLEGPR ; 141.59 0.00072748 23363000 739.01 782.3 664.78 766.5 636.11 907.89 719.88 1065.4 930.77 637.27 TRUE FALSE FALSE 680.5165787 849.9185261 689.4173316 763.3284261 628.5248037 719.58338 740.0778953 1390.235556 828.6668597 659.4150851 1.03200032 1.288897608 1.045498271 1.157584113 0.953155028 1.091244948 1.122324788 2.108285945 1.256669552 1 9.365043081 -4.256799797 4.08619121 1.048245829 2.203451318 0.874179671 0.112643983 0.045511183 1.617897355 0.013017265 0.155099539 5.54E-05 4.256799797 1.155205489 up LGS(ph)PPPHK ddPTM_HeLa_Curcumin_4h_R1 1 LGSPPPHK 8 0 E9PJM7;E7EMB1;Q9UH65 E9PJM7 SWAP70 Switch-associated protein 70 1 0 LGS(1)PPPHK 77.662 0.016348 6977200 8201.3 7158.4 7176.7 8032.2 7116.6 8371.4 6725 5732.9 7972.6 7610.6 TRUE FALSE FALSE 7552.158451 7777.140199 7442.674815 7998.964885 7031.739193 6635.077275 6913.685401 7480.834819 7098.025726 7875.067784 0.958995993 0.987564858 0.945093429 1.01573283 0.892911577 0.842542243 0.877920748 0.949939102 0.901328842 1 12.94307663 -5.711974231 9.029060941 0.979975995 0.886162426 0.46133767 0.03957124 0.143140803 24.34909343 0.004525994 0.009043763 1.94E-06 5.711974231 -0.093813569 LDSSEMDHS(ph)ENEDYTMSSPLPGK ddPTM_HeLa_Curcumin_4h_R1 1 LDSSEMDHSENEDYTMSSPLPGK 23 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 LDS(0.035)S(0.032)EMDHS(0.461)ENEDY(0.406)T(0.044)MS(0.016)S(0.006)PLPGK 45.413 0.018712 40327000 4931 3582.5 4502.5 5311.5 5233.4 5084.5 3687.2 1874 5580.6 5028 TRUE FALSE FALSE 4540.706147 3892.155337 4669.366611 5289.52242 5170.995123 4029.917386 3790.652908 2445.373973 4968.422142 5202.722626 0.872755761 0.748099719 0.89748521 1.016683533 0.99390175 0.774578557 0.728590237 0.470018133 0.954965794 1 12.34505108 -4.383923829 1.277959437 0.928502994 0.340881406 0.750822627 0.080458239 0.466942494 0.755385713 0.013585148 0.336595668 4.13E-05 4.383923829 -0.587621588 down LGS(ph)VDSFER ddPTM_HeLa_Curcumin_4h_R1 3 LGSVDSFER 9 0 A0A3B3IRT3;O60343-2;O60343-3;O60343;Q5JU47 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 1 0 LGS(0.618)VDS(0.382)FER;LGS(0.993)VDS(0.007)FER;LGS(0.799)VDS(0.201)FER ;; 136.02 0.0029724 750792000 6915 6453.2 7129.7 7266.1 6909 9004.6 7583 7769.9 7532.3 7774.2 TRUE FALSE FALSE 6367.670453 7010.985853 7393.932954 7236.034803 6826.614687 7136.944457 7795.758571 10138.90674 6706.025535 8044.352871 0.791570255 0.871541312 0.919145775 0.899517328 0.848621983 0.887199327 0.969097042 1.260375683 0.833631448 1 12.97376065 -4.259883668 2.584402144 0.894155111 1.338154283 0.816421754 0.053670161 0.22465207 1.896306934 0.010780104 0.216442396 5.50E-05 4.259883668 0.443999172 LGS(ph)YSGPTSVSR ddPTM_HeLa_Curcumin_4h_R1 1 LGSYSGPTSVSR 12 0 A0A2R8YFI4;V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23 A0A2R8YFI4 PANK2 "Pantothenate kinase 2, mitochondrial" 1 0 LGS(0.945)YS(0.055)GPTSVSR 161.25 0.00018951 54621000 945.43 1142.3 958.62 1127.7 1192.6 1419.7 1438.5 1336.7 1178.2 986.2 TRUE FALSE FALSE 870.5982179 1241.035322 994.1473005 1123.033876 1178.379024 1125.238217 1478.860438 1744.253677 1048.954408 1020.470377 0.853134239 1.216140469 0.974204958 1.100506102 1.15474104 1.102666224 1.449194874 1.709264391 1.027912649 1 9.995018587 -1 0.438411 0.944146588 17.67012577 0.821741801 0.100539169 19.56472885 0.216136223 0.023071677 293.3651754 0.1 1 16.72597918 LGSAPAASPALAS(ph)PEGPK ddPTM_HeLa_Curcumin_4h_R1 1 LGSAPAASPALASPEGPK 18 0 Q6ZUT6-4;Q6ZUT6;Q6ZUT6-2 Q6ZUT6-4 C15orf52 Uncharacterized protein C15orf52 1 0 LGSAPAAS(0.001)PALAS(0.999)PEGPK 160.76 4.14E-13 0 1779.7 1363.4 1641.9 1513.7 1849.6 1420.7 973.73 1324 1749.5 1452.6 TRUE FALSE FALSE 1638.834867 1481.246221 1702.750258 1507.43671 1827.544728 1126.030805 1001.050243 1727.681505 1557.584227 1503.077742 1.09031943 0.985475454 1.132842441 1.002900029 1.215868399 0.749150077 0.666000311 1.149429239 1.036263251 1 10.55370391 -5.248733668 24.99206662 1.053042822 0.835973918 0.338202449 0.133838752 610.603734 1201051.614 0.017279088 0.04371871 5.64E-06 5.248733668 -0.217068904 ATSAGSS(ph)PSCSLAGR ddPTM_HeLa_Curcumin_4h_R1 1 ATSAGSSPSCSLAGR 15 0 Q9BXB5-2;Q9BXB5 Q9BXB5-2 OSBPL10 Oxysterol-binding protein-related protein 10 1 0 ATSAGS(0.085)S(0.869)PS(0.043)CS(0.004)LAGR 201.72 2.44E-09 100040000 4021.5 3052.1 3105.6 3473.5 3085.5 3656.2 2004.9 615.46 4011.7 2993.9 TRUE FALSE FALSE 3703.194032 3315.909924 3220.696268 3459.127577 3048.707428 2897.862906 2061.152098 803.1109208 3571.626547 3097.937802 1.195373913 1.070360393 1.039625865 1.11659039 0.984108663 0.935416749 0.665330368 0.259240492 1.152904537 1 11.59709246 -4.383747328 1.159516909 1.088259954 1.71E-19 0.954573132 0.056913845 0.244337712 0.309324369 0.011390557 0.303465964 4.13E-05 4.383747328 -1.088259954 down LGSLVDEFK ddPTM_HeLa_Curcumin_4h_R1 2 LGSLVDEFK 9 0 P12956;P12956-2;B1AHC9 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 0 ; ; 116.52 0.0016178 1098190 1327.57 1118.71 1354.83 992.18 868.52 932.54 1147.02 846.74 832.35 395.37 FALSE FALSE TRUE 1222.491434 1215.406308 1405.041192 988.0746221 858.1634662 739.1206921 1179.202294 1104.907128 741.0432874 409.1090781 2.988179679 2.970861251 3.434392603 2.415186255 2.097639755 1.80665923 2.882366482 2.700764142 1.811358699 1 8.676341741 -9.289674389 0.990350117 0.989374846 2.664347337 0.475613896 0.502433183 0.291139213 0.506720653 0.345984413 0.090811087 5.13E-10 9.289674389 1.674972492 SLS(ph)ESSVIMDR ddPTM_HeLa_Curcumin_4h_R1 4 SLSESSVIMDR 11 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BNX5 H3BSS6 ZNF106 Zinc finger protein 106 1 0 S(0.003)LS(0.514)ES(0.242)S(0.242)VIMDR;S(0.001)LS(0.889)ES(0.055)S(0.055)VIMDR;S(0.003)LS(0.995)ES(0.002)SVIMDR;S(0.003)LS(0.99)ES(0.004)S(0.004)VIMDR ;;; 198.97 7.08E-06 245769000 19838 16731.1 18928.1 17998.9 16975.2 19438.8 10601.77 3761.44 20854.2 17634 TRUE FALSE FALSE 18267.80137 18177.26173 19629.59204 17924.42532 16772.78183 15406.97376 10899.22713 4908.28574 18566.54643 18246.78019 1.001152049 0.996190097 1.075783883 0.982333603 0.919218714 0.84436671 0.59732331 0.268994622 1.01752453 1 14.15535429 -4.382170583 1.070484863 1.004972839 4.32E-20 0.986788934 0.027330281 0.108669908 0.112554839 0.004165542 0.117352943 4.15E-05 4.382170583 -1.004972839 down LGSQHS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 3 LGSQHSPGR 9 0 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 0 LGS(0.015)QHS(0.985)PGR;LGS(0.002)QHS(0.998)PGR;LGS(0.286)QHS(0.714)PGR ;; 97.452 0.0069097 25557800 11108.5 18124.3 8172.7 7136.3 10906.8 17715.6 5610.9 3141.9 9771.6 9172.1 TRUE FALSE FALSE 10229.2505 19690.88373 8475.587451 7106.771881 10776.74353 14041.18486 5768.326753 4099.850846 8699.679927 9490.829792 1.077803599 2.074727307 0.893029128 0.74880406 1.135490128 1.479447548 0.60777897 0.431980231 0.916640601 1 13.21231851 -4.60776142 6.936950985 1.111031806 0.47516925 0.335819423 0.360243831 0.173646132 11.5001201 0.048867698 0.186534095 2.47E-05 4.60776142 -0.635862556 LGSQPIRAS(ph)NPDLR ddPTM_HeLa_Curcumin_4h_R1 2 LGSQPIRASNPDLR 14 1 Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3;Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5 Q9UKE5-8 TNIK TRAF2 and NCK-interacting protein kinase 1 0 LGSQPIRAS(1)NPDLR;LGSQPIRAS(1)NPDLR ; 85.536 0.0061415 47185000 6660 6068.7 6233.5 5750.2 6858.3 7880.1 6533.8 7263.3 7703.4 5740.5 TRUE FALSE FALSE 6132.853972 6593.251386 6464.518994 5726.407196 6776.519252 6245.678433 6717.120843 9477.846734 6858.356293 5939.981948 1.032470137 1.109978354 1.088306168 0.964044545 1.140831624 1.051464211 1.130831861 1.595601942 1.154608946 1 12.53624283 -4.111592194 1.89555797 1.033441434 1.946845095 0.850816937 0.06459232 0.272811925 0.72340441 0.007655841 0.497351326 7.73E-05 4.111592194 0.913403662 LGSVDS(ph)FER ddPTM_HeLa_Curcumin_4h_R1 2 LGSVDSFER 9 0 A0A3B3IRT3;O60343-2;O60343-3;O60343;Q5JU47 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 1 0 LGSVDS(1)FER;LGSVDS(1)FER ; 126.03 0.0046748 76759000 5131.4 2637.4 2985.3 3098 3223.1 10184 8502.7 1517.99 3255.7 2337.87 TRUE FALSE FALSE 4725.244275 2865.365104 3095.937844 3085.181297 3184.666638 8071.723603 8741.262878 1980.818163 2898.557855 2419.110808 1.953297988 1.184470382 1.279783395 1.275336907 1.316461663 3.336648976 3.613419794 0.818820765 1.198191437 1 11.24026114 -5.277884541 24.42075795 1.405136717 2.692008828 0.382194447 0.732799723 436.3373674 647952.6234 0.103376034 0.231836117 5.27E-06 5.277884541 1.286872111 DLELALS(ph)PIHNSSALPTTGR ddPTM_HeLa_Curcumin_4h_R1 1 DLELALSPIHNSSALPTTGR 20 0 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 1 0 DLELALS(1)PIHNSSALPTTGR 88.856 0.00064809 5990600 2684.8 2385.3 1889.3 1852 2291.1 2853.3 1624.3 664.52 2915.9 1898.7 TRUE FALSE FALSE 2472.295247 2591.474703 1959.31912 1844.336915 2263.780129 2261.493417 1669.873486 867.1290889 2596.033065 1964.679684 1.258370648 1.319031659 0.997271533 0.938746876 1.152238784 1.151074873 0.849946941 0.441359014 1.321351815 1 10.9400784 -4.382161982 2.213624049 1.12071046 0.354858108 0.738418622 0.129157259 0.199401399 1.3380316 0.019239167 0.268457744 4.15E-05 4.382161982 -0.765852352 down SSFLSS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 2 SSFLSSPER 9 0 Q4AC94 Q4AC94 C2CD3 C2 domain-containing protein 3 1 0 SSFLS(0.069)S(0.931)PER;SSFLS(0.19)S(0.81)PER ; 128.86 0.0040983 16077800 8146.9 4483.5 5642 6055.6 6533.5 6831.2 3408.4 1709.4 6267.6 6201.2 TRUE FALSE FALSE 7502.064268 4871.033762 5851.097483 6030.543532 6455.59228 5414.332117 3504.030531 2230.588191 5580.059961 6416.691238 1.169148396 0.759119238 0.911855856 0.939821367 1.006062477 0.843788787 0.546080589 0.347622802 0.869616404 1 12.64761385 -4.380069232 0.776366435 1.045026935 2.91E-21 0.703342393 0.123350844 0.787581199 0.375325847 0.021100823 0.684582825 4.17E-05 4.380069232 -1.045026935 down LGTSES(ph)LPCTAEELSR ddPTM_HeLa_Curcumin_4h_R1 1 LGTSESLPCTAEELSR 16 0 Q9BZL6-2;Q9BZL6;Q9BZL6-3 Q9BZL6-2 PRKD2 Serine/threonine-protein kinase D2 1 0 LGTS(0.004)ES(0.989)LPCT(0.007)AEELSR 99.711 0.0029837 16233000 1056.1 875.49 1378.1 1157.1 933.55 1169.8 894.93 1159 939.76 1289.2 TRUE FALSE FALSE 972.5085706 951.1634545 1429.173598 1152.312227 922.418026 927.1702936 920.0393272 1512.373765 836.6706792 1333.999604 0.729017136 0.713016294 1.071344844 0.863802525 0.691467991 0.695030411 0.689684858 1.133713803 0.627189601 1 10.38154252 -5.961084412 24.82951557 0.872251246 0.785604719 0 0.175878077 387.0761799 246966.4586 0.025304184 0.045867676 1.09E-06 5.961084412 -0.086646527 LGVIEDHSNR ddPTM_HeLa_Curcumin_4h_R1 4 LGVIEDHSNR 10 0 P14625;Q58FF3 P14625;Q58FF3 HSP90B1;HSP90B2P Endoplasmin;Putative endoplasmin-like protein 0 0 ;;; ;;; 159.34 0.00049376 32643500 23367 16818.9 23097.7 21324.8 21775.7 24914.9 15306.8 10826.1 21841.8 20794.7 FALSE FALSE TRUE 21517.47729 18272.65077 23953.72108 21236.56363 21516.039 19747.26889 15736.26761 14126.92805 19445.80919 21517.31428 1.000007576 0.849206854 1.113230061 0.986952338 0.999940732 0.917738554 0.731330472 0.656537701 0.903728455 1 14.3932104 -4.764085666 2.109081601 0.996312159 0.655475021 0.741574521 0.06650169 0.099402922 0.823895604 0.007921957 0.043713478 1.72E-05 4.764085666 -0.340837138 LGVSVS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 3 LGVSVSPSR 9 0 E7ERS3;Q86VM9;H3BP01 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 0 LGVS(0.003)VS(0.959)PS(0.038)R;LGVS(0.006)VS(0.953)PS(0.042)R;LGVS(0.002)VS(0.997)PS(0.001)R ;; 108.31 0.009695 1620576000 14597.2 11528.2 12427.8 12759.2 12911.7 14534.7 13202.6 11969.4 13340.6 12068.9 TRUE FALSE FALSE 13441.81622 12524.64624 12888.3852 12706.40581 12757.73641 11520.03938 13573.02942 15618.81496 11877.16956 12488.29338 1.076353334 1.002910955 1.03203735 1.017465352 1.021575649 0.922467068 1.086860231 1.250676493 0.951064265 1 13.60828871 -4.332492689 3.565524884 1.025211189 1.261931853 0.719720064 0.045345518 0.098107114 2.080869726 0.006014104 0.053972978 4.65E-05 4.332492689 0.236720665 NSNNEVACK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 NSNNEVACKK 10 1 Q9H967;C9JE56;A0A0C4DFX7 Q9H967 WDR76 WD repeat-containing protein 76 0 1 NSNNEVACK(1)K 114.86 0.0013124 1038400 869.74 663.49 582.64 606.81 604.35 786.24 413.25 29.141 484.87 507.01 FALSE TRUE FALSE 800.8991613 720.8391191 604.2331509 604.299181 597.143521 623.1649612 424.8446828 38.02595675 431.6809741 524.6285598 1.526602291 1.373999005 1.151735146 1.151861007 1.138221528 1.187821268 0.809800906 0.072481675 0.822831632 1 9.035152537 -4.413114472 2.071125423 1.240695197 1.05E-15 0.74681196 0.190940479 0.192685358 1.135302874 0.029157949 0.395001467 3.86E-05 4.413114472 -1.240695197 down LHAEFAAERDWEQFHQPR ddPTM_HeLa_Curcumin_4h_R1 2 LHAEFAAERDWEQFHQPR 18 1 Q9H773 Q9H773 DCTPP1 dCTP pyrophosphatase 1 0 0 ; ; 86.777 0.00094291 29055000 2723.6 3031.5 2321.15 2557.4 2733 4929.6 2974.8 2551 3831.1 4117.7 FALSE FALSE TRUE 2508.024186 3293.529352 2407.173861 2546.818156 2700.41076 3907.145392 3058.264882 3328.788157 3410.837915 4260.789769 0.588628945 0.772985651 0.564959548 0.597733823 0.633781742 0.917000276 0.717769486 0.781260831 0.800517768 1 12.05690515 -9.412313893 1.091282362 1.003330105 0.688392802 0.266149156 0.118356248 0.321645901 0.673472619 0.078596894 0.019061811 3.87E-10 9.412313893 -0.314937303 LHDFGYR ddPTM_HeLa_Curcumin_4h_R1 2 LHDFGYR 7 0 A0A0C4DFS8;P43490 A0A0C4DFS8 NAMPT Nicotinamide phosphoribosyltransferase 0 0 ; ; 190.71 0.00022149 31157000 3733.5 2479.5 3364.3 2993.8 3650.7 4454.7 3294.7 3145.4 3690 3429.9 FALSE FALSE TRUE 3437.989535 2693.816932 3488.983918 2981.412449 3607.167787 3530.745005 3387.140415 4104.41798 3285.216232 3549.08877 0.968696406 0.759016499 0.983064709 0.840050121 1.016364487 0.994831416 0.954369032 1.156470927 0.925650623 1 11.79323294 -4.260179288 24.16211041 0.961215853 1.156471021 0.376569331 0.079426947 58.77396135 1126765.747 0.010858412 0.090010596 5.49E-05 4.260179288 0.195255168 LHEEGIIYR ddPTM_HeLa_Curcumin_4h_R1 1 LHEEGIIYR 9 0 A0A140T936;P26640-2;P26640 A0A140T936 VARS Valine--tRNA ligase 0 0 106.68 0.0081589 10677000 1751.3 1660 1548.9 1782.8 1768.8 1603.3 1344.5 1286.3 1811.3 1508.1 FALSE FALSE TRUE 1612.682757 1803.483003 1606.303597 1775.423246 1747.708215 1270.757507 1382.223051 1678.486949 1612.604922 1560.506363 1.033435554 1.155703717 1.029347675 1.137722529 1.119962249 0.814323823 0.88575291 1.07560404 1.033385675 1 10.60779852 -5.270289903 24.89959952 1.043323506 0.92127952 0.374309099 0.081363689 550.0491891 1547480.604 0.012071324 0.027384986 5.37E-06 5.270289903 -0.122043987 LHELRIARLRQEER ddPTM_HeLa_Curcumin_4h_R1 1 LHELRIARLRQEER 14 3 Q9BYN8 Q9BYN8 MRPS26 "28S ribosomal protein S26, mitochondrial" 0 0 61.375 0.014121 33063000 5968.5 5133.8 5226.4 5337 5613.9 6121.6 5131.9 5452.1 5050.9 4571.6 FALSE FALSE TRUE 5496.086927 5577.542796 5420.094982 5314.916908 5546.957909 4851.911155 5275.887302 7114.420192 4496.828907 4730.46276 1.16184974 1.179069169 1.145785361 1.123551157 1.172603652 1.025673682 1.115300462 1.503958609 0.950610783 1 12.20776561 -1.000000003 0.021047893 2.61E-11 2.652495815 0.383085709 0.112440983 2398.496833 3.928719447 181.4857042 336.0697114 0.099999999 1.000000003 2.652495815 LHFFMPGFAPLTSR ddPTM_HeLa_Curcumin_4h_R1 4 LHFFMPGFAPLTSR 14 0 Q5JP53;P07437;Q5ST81;A0A075B736;Q5SQY0;A6NNZ2;P04350;P68371;Q3ZCM7;Q9BVA1;Q13885;Q9BUF5;K7ESM5 Q5JP53;P04350;P68371;Q9BVA1;Q9BUF5 TUBB;TUBB8;TUBB4A;TUBB4B;TUBB2B;TUBB2A;TUBB6 Tubulin beta chain;Tubulin beta-8 chain-like protein LOC260334;Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-8 chain;Tubulin beta-2B chain;Tubulin beta-2A chain;Tubulin beta-6 chain 0 0 ;;; ;;; 100.19 0.0019405 35389540 4555.19 1316.96 3363.79 1831.89 3153.16 9842.98 6246.37 4849.61 2761.2 3373.41 FALSE FALSE TRUE 4194.641905 1430.792154 3488.455016 1824.310125 3115.560626 7801.434995 6421.626331 6328.233764 2458.303268 3490.635746 1.201684223 0.409894431 0.999375263 0.522629761 0.892548193 2.234961068 1.839672426 1.812917252 0.704256602 1 11.7692741 -5.268582273 24.92308018 0.981453032 1.950232477 0.765845 0.279867199 211.1297637 736677.8288 0.041620097 0.094925188 5.39E-06 5.268582273 0.968779444 LHGELQDR ddPTM_HeLa_Curcumin_4h_R1 2 LHGELQDR 8 0 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 0 0 ; ; 148.99 0.0016388 27828200 2861.8 3006.5 3290.1 3297 3282.8 4227.4 3344.5 2438.3 3897.3 3494.4 FALSE FALSE TRUE 2635.28551 3266.368463 3412.034 3283.357888 3243.654754 3350.589587 3438.337669 3181.726445 3469.775941 3615.83014 0.728818946 0.903352297 0.943637801 0.908050921 0.897070556 0.926644631 0.950912387 0.87994356 0.959607008 1 11.82011119 -7.014317687 24.4611675 0.869002461 0.918685352 0 0.069876127 1328.827905 2270247.257 0.016661497 0.020841023 9.68E-08 7.014317687 0.049682891 LHGGFDS(ph)DCS(ph)EDGEALNGEPELDLTSK ddPTM_HeLa_Curcumin_4h_R1 1 LHGGFDSDCSEDGEALNGEPELDLTSK 27 0 O00178;F8WAZ4 O00178 GTPBP1 GTP-binding protein 1 2 0 LHGGFDS(1)DCS(1)EDGEALNGEPELDLTSK 68.97 0.001023 12397000 2595.5 1927.2 1873.9 2055.4 2517 2551.9 1703.5 1465.5 2842.5 2578 TRUE FALSE FALSE 2390.063436 2093.778581 1943.348382 2046.895299 2486.986419 2022.607174 1751.295625 1912.324204 2530.684862 2667.585308 0.895965137 0.784896578 0.72850468 0.767321402 0.932298739 0.758216492 0.656509698 0.71687462 0.948680012 1 11.38131869 -7.119139566 0.137704931 1.165836522 0.533682955 0.606812161 0.068943385 2.541991211 0.292311761 0.566598935 0.657631974 7.60E-08 7.119139566 -0.632153567 LHIVQVVCK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 LHIVQVVCKK 10 1 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 0 1 ; LHIVQVVCK(1)K;LHIVQVVCK(1)K 98.048 0.0027688 4503900 3721.5 3359.5 3033.2 3053.7 5173.9 9659.7 6793.1 7232.5 9454 4061.2 FALSE TRUE FALSE 3426.939348 3649.88021 3145.61306 3041.064599 5112.204622 7656.169333 6983.696103 9437.655956 8416.919853 4202.326398 0.815486239 0.868538011 0.748540871 0.72366216 1.216517742 1.821888309 1.661864273 2.245816974 2.002919111 1 12.03697251 -5.334972791 2.257628154 0.881079753 1.933658255 0.490858056 0.387225521 0.069462554 0.683989852 0.023311017 0.065205656 4.62E-06 5.334972791 1.052578502 LHKTEDGGWEWS(ph)DDEFDEESEEGK ddPTM_HeLa_Curcumin_4h_R1 2 LHKTEDGGWEWSDDEFDEESEEGK 24 1 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 0 LHKT(0.008)EDGGWEWS(0.991)DDEFDEES(0.001)EEGK;LHKTEDGGWEWS(0.999)DDEFDEES(0.001)EEGK ; 83.064 7.41E-05 135827000 6842.7 6736.5 7179.8 6846.8 7376.9 7789.1 6612 6985 8709.2 7453.9 TRUE FALSE FALSE 6301.093075 7318.773043 7445.889704 6818.469756 7288.935286 6173.552859 6797.514925 9114.694345 7753.822549 7712.92247 0.816952731 0.948897525 0.965378523 0.884031932 0.945028984 0.800416818 0.881315085 1.181743286 1.005302799 1 12.91306189 -4.257873773 24.54707041 0.908735157 1.18174342 0.581096177 0.067314412 163.7491714 1127249.373 0.010537613 0.103635037 5.52E-05 4.257873773 0.273008263 LHKTEDGGWEWS(ph)DDEFDEESEEGKAAISQLR ddPTM_HeLa_Curcumin_4h_R1 3 LHKTEDGGWEWSDDEFDEESEEGKAAISQLR 31 2 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 0 LHKT(0.009)EDGGWEWS(0.989)DDEFDEES(0.002)EEGKAAISQLR;LHKT(0.032)EDGGWEWS(0.962)DDEFDEES(0.005)EEGKAAISQLR;LHKT(0.005)EDGGWEWS(0.993)DDEFDEES(0.002)EEGKAAISQLR ;; 60.419 0.0003794 41117800 3859.85 2784.89 2865.79 3169.07 2284.89 3644.84 2556.21 2925.73 5185.13 3791.78 TRUE FALSE FALSE 3554.3388 3025.603482 2971.998698 3155.957228 2257.644179 2888.859098 2627.930373 3817.771609 4616.334212 3923.544073 0.905900057 0.771140435 0.757478097 0.804363904 0.57540941 0.736288173 0.669784849 0.973041602 1.176572539 1 11.93794169 -7.421352614 1.032256842 0.974635119 0.735966557 0.525317405 0.115983458 0.254839354 0.54282587 0.020870878 0.022902379 3.79E-08 7.421352614 -0.238668562 SDDY(ph)MPMSPASVSAPK ddPTM_HeLa_Curcumin_4h_R1 2 SDDYMPMSPASVSAPK 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 S(0.01)DDY(0.979)MPMS(0.01)PASVSAPK;S(0.001)DDY(0.992)MPMS(0.007)PASVSAPK ; 101.89 0.00053537 11643000 6154 4834.8 5501.8 5663.8 5621.5 7119.9 4102.9 1716.08 6189.3 5011 TRUE FALSE FALSE 5666.904406 5252.698569 5705.701548 5640.364696 5554.467284 5643.152482 4218.016332 2239.304892 5510.349275 5185.131877 1.092914229 1.013030853 1.100396612 1.087795803 1.071229704 1.088333453 0.813482942 0.431870383 1.062721143 1 12.34016497 -4.377894201 2.285257227 1.054283995 0.356495619 0.965108788 0.037137574 0.07014783 0.508229845 0.006451081 0.0878837 4.19E-05 4.377894201 -0.697788376 down LHQLAMQQSHFPMTHGNTGFSGIES(ph)SSPEVK ddPTM_HeLa_Curcumin_4h_R1 1 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVK 31 0 Q15366;Q15366-2;Q15366-3;Q15366-6;Q15366-5;H3BRU6;F8VZX2;Q15366-4;F8VRH0 Q15366 PCBP2 Poly(rC)-binding protein 2 1 0 LHQLAMQQSHFPMTHGNT(0.02)GFS(0.007)GIES(0.691)S(0.141)S(0.141)PEVK 105.17 5.37E-11 45064000 832.72 969.83 775.19 557.27 997.32 3300.8 1396.2 576.28 1296.3 795.37 TRUE FALSE FALSE 766.8093333 1053.657784 803.9192233 554.9641644 985.4276104 2616.176872 1435.373614 751.9851191 1154.099133 823.0090483 0.931714341 1.280250546 0.976804842 0.674311134 1.197347237 3.178794787 1.744055691 0.913702128 1.402292157 1 9.684764482 -5.501240905 24.87670716 0.973873385 1.969154716 0.349825475 0.547493796 503.0585385 578358.4982 0.071697399 0.158906236 3.15E-06 5.501240905 0.99528133 LHQLAMQQSHFPMTHGNTGFSGIESS(ph)SPEVK ddPTM_HeLa_Curcumin_4h_R1 2 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVK 31 0 Q15366;Q15366-2;Q15366-3;Q15366-6;Q15366-5;H3BRU6;F8VZX2;Q15366-4;F8VRH0 Q15366 PCBP2 Poly(rC)-binding protein 2 1 0 LHQLAMQQSHFPMTHGNT(0.003)GFS(0.037)GIES(0.058)S(0.451)S(0.451)PEVK;LHQLAMQQS(0.001)HFPMT(0.013)HGNT(0.013)GFS(0.013)GIES(0.054)S(0.454)S(0.454)PEVK ; 73.175 4.34E-05 97113000 2038.94 1841.39 1702.69 1469.62 2417.9 7952.4 3875.8 2041.19 2813.6 1766.24 TRUE FALSE FALSE 1877.555748 2000.551547 1765.793189 1463.539102 2389.068122 6302.982598 3984.544517 2663.539435 2504.955119 1827.616709 1.027324679 1.094623143 0.966172601 0.800791049 1.307204137 3.448744241 2.180186085 1.457384047 1.370612945 1 10.83574782 -5.499336155 22.83431599 1.004907828 2.349590579 0.611875758 0.470993514 111.0139834 107673.5276 0.06110666 0.13564172 3.17E-06 5.499336155 1.344682751 LHQLAMQQSHFPMTHGNTGFSGIESSS(ph)PEVK ddPTM_HeLa_Curcumin_4h_R1 1 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVK 31 0 Q15366;Q15366-2;Q15366-3;Q15366-6;Q15366-5;H3BRU6;F8VZX2;Q15366-4;F8VRH0 Q15366 PCBP2 Poly(rC)-binding protein 2 1 0 LHQLAMQQSHFPMTHGNTGFSGIES(0.004)S(0.123)S(0.873)PEVK 99.443 6.69E-09 47214000 1635.9 1557.5 1265.9 944.35 2108.5 5776 2343 1468.7 1893.7 1294.2 TRUE FALSE FALSE 1506.416789 1692.12336 1312.815368 940.4425299 2083.357515 4577.992491 2408.738274 1916.499869 1685.965848 1339.173354 1.124885576 1.263558116 0.980317719 0.702256005 1.555704128 3.418521193 1.79867548 1.431106633 1.258960121 1 10.38712701 -5.517847438 24.68333862 1.051763373 2.226484243 0.523987692 0.49595077 99.1288827 486320.0806 0.067670318 0.138520806 3.03E-06 5.517847438 1.17472087 LHQVIHTGEKPYK ddPTM_HeLa_Curcumin_4h_R1 2 LHQVIHTGEKPYK 13 1 Q86WZ6-2;Q86WZ6 Q86WZ6-2 ZNF227 Zinc finger protein 227 0 0 ; ; 84.821 0.015047 74829000 10347.4 8271 9407.4 9637 10132.4 11563.6 9892.6 9600.1 9829.9 8561.2 FALSE FALSE TRUE 9528.392371 8985.908385 9756.04652 9597.124647 10011.57775 9165.179011 10170.15973 12527.1263 8751.584563 8858.701063 1.07559701 1.014359591 1.101295376 1.08335574 1.130140602 1.034596263 1.14804187 1.414104191 0.987908329 1 13.11287946 -1.080811169 0.934594568 1.04521828 200 0.857293932 0.044202872 242.5973709 0.511377071 0.007105708 103029.2945 0.083021167 1.080811169 198.9547817 LHS(ph)PGATSTAELGSR ddPTM_HeLa_Curcumin_4h_R1 2 LHSPGATSTAELGSR 15 0 H7C0P0;Q9BV73-2;Q9BV73 H7C0P0 CEP250 Centrosome-associated protein CEP250 1 0 LHS(0.794)PGAT(0.028)S(0.028)T(0.149)AELGS(0.001)R;LHS(0.426)PGAT(0.126)S(0.126)T(0.316)AELGS(0.005)R ; 108.58 0.0035144 4316800 1885.77 2017.69 1459.05 1489.75 1863.56 2204.17 1451.98 1297.42 2110.1 1582.32 TRUE FALSE FALSE 1736.509315 2192.090133 1513.123677 1483.585809 1841.338264 1747.000296 1492.718651 1692.997385 1878.627309 1637.305502 1.060589678 1.338840021 0.924154762 0.906114227 1.124614961 1.066997145 0.911692197 1.03401435 1.147389602 1 10.67710782 LHS(ph)PQTHWK ddPTM_HeLa_Curcumin_4h_R1 1 LHSPQTHWK 9 0 Q9H8Y5;B8ZZS4 Q9H8Y5 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 0 LHS(0.998)PQT(0.002)HWK 83.617 0.0063435 0 5777.6 4444.3 4655.2 4669.9 4504.4 5721 4270.3 2870.5 5612.5 4586.2 TRUE FALSE FALSE 5320.296864 4828.445489 4827.725807 4650.577191 4450.687972 4534.400111 4390.113125 3745.702236 4996.822792 4745.570109 1.121108053 1.017463735 1.017312082 0.979982823 0.937861599 0.955501659 0.925097096 0.789305004 1.052944678 1 12.2123657 -3.897272772 0.46995005 1.054673114 0.55177313 0.792532704 0.038158098 2.591077908 0.301895292 0.011782991 0.776619188 0.000126686 3.897272772 -0.502899983 LHS(ph)SNPNLSTLDFGEEKNYSDGSETSSEFSK ddPTM_HeLa_Curcumin_4h_R1 1 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSK 31 1 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 0 LHS(0.486)S(0.486)NPNLS(0.014)T(0.014)LDFGEEKNY(0.001)SDGSETSSEFSK 56.374 0.00080202 10071000 1960.1 1017.7 1138.9 1378.3 1014.3 1794.5 802.4 569.32 2218.8 1700.9 TRUE FALSE FALSE 1804.956017 1105.665453 1181.108636 1372.59696 1002.205135 1422.300472 824.9131845 742.9030472 1975.403191 1760.006148 1.025539609 0.628216813 0.671082108 0.779881912 0.569432747 0.808122445 0.468699036 0.422102529 1.122384256 1 10.78136475 -7.260216864 24.51779649 1.012060377 0.628455027 0.729498419 0.118791023 32.32482036 648281.675 0.019090197 0.022691526 5.49E-08 7.260216864 -0.383605349 LHSFLGDDVFLR ddPTM_HeLa_Curcumin_4h_R1 2 LHSFLGDDVFLR 12 0 E9PK47;P06737-2;P06737 E9PK47 PYGL "Alpha-1,4 glucan phosphorylase;Glycogen phosphorylase, liver form" 0 0 ; ; 159.44 0.00018888 19938100 5756 4412.4 4901 5068.5 4575.9 6725.8 5287.6 5425.9 5711.6 4779.7 FALSE FALSE TRUE 5300.406526 4793.788195 5082.635371 5047.52789 4521.335381 5330.793265 5435.955825 7080.231932 5085.05177 4945.794219 1.07169977 0.969265599 1.027668186 1.020569734 0.914177821 1.077843725 1.099106753 1.431566219 1.028156762 1 12.2719865 -4.138938178 1.870680891 1.021774451 1.658608149 0.886609138 0.044748672 0.305221314 0.836868577 0.006813235 0.374444393 7.26E-05 4.138938178 0.636833698 LHSLQVLVLSNNALRTLR ddPTM_HeLa_Curcumin_4h_R1 1 LHSLQVLVLSNNALRTLR 18 1 A6NM62 A6NM62 LRRC53 Leucine-rich repeat-containing protein 53 0 0 34.909 0.017854 12939000 6866 6580.2 4797.4 8961.1 4449.8 5497.5 5513.7 6110 6459 8161.5 FALSE FALSE TRUE 6322.548855 7148.963167 4975.195864 8924.021343 4396.739041 4357.25653 5668.399583 7972.910873 5750.46386 8445.111518 0.74866375 0.846520872 0.589121393 1.056708526 0.520625338 0.515950147 0.671204823 0.94408592 0.680922194 1 13.04390076 -9.591010048 0.333924845 1.146330122 0.697009211 0 0.194483278 3.973972727 0.487365112 0.682701275 0.074829907 2.56E-10 9.591010048 -0.449320911 LHSS(ph)NPNLSTLDFGEEK ddPTM_HeLa_Curcumin_4h_R1 2 LHSSNPNLSTLDFGEEK 17 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 0 LHS(0.034)S(0.966)NPNLSTLDFGEEK;LHS(0.032)S(0.968)NPNLSTLDFGEEK ; 196.45 8.47E-08 63381000 6288.8 5490.1 6125.4 6550.2 7186.2 6309.7 3446.6 3269.4 6260.7 5438.9 TRUE FALSE FALSE 5791.034844 5964.639781 6352.412712 6523.097008 7100.509258 5000.997095 3543.30232 4266.22501 5573.916873 5627.90137 1.028986555 1.059833744 1.128735615 1.159063846 1.261661993 0.888607807 0.629595668 0.758049001 0.990407704 1 12.45838133 -4.979576823 5.446768127 1.052897825 0.703069776 0.761520798 0.087643376 0.070277423 6.30227303 0.013540806 0.040572576 1.05E-05 4.979576823 -0.349828049 LHSYS(ph)SPSTK ddPTM_HeLa_Curcumin_4h_R1 4 LHSYSSPSTK 10 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 0 LHSYS(0.808)S(0.189)PS(0.002)TK;LHSYS(0.803)S(0.194)PS(0.003)TK;LHS(0.011)YS(0.6)S(0.359)PS(0.024)T(0.006)K;LHS(0.001)YS(0.735)S(0.241)PS(0.022)T(0.001)K ;;; 208.33 4.95E-07 148411000 24593.2 18890.7 18800.7 18173.1 24731.2 32920.2 24925.6 8263.6 26175.7 19256.5 TRUE FALSE FALSE 22646.62227 20523.52793 19497.47048 18097.90453 24436.29659 26092.17943 25624.94525 10783.1336 23304.2912 19925.66194 1.13655558 1.030004825 0.978510553 0.908271182 1.22637314 1.309476167 1.286027301 0.541168149 1.169561707 1 14.28234003 -5.745465672 24.99479947 1.046184885 1.120331194 0.006297103 0.214310369 883.6426778 1382668.363 0.029488016 0.058821396 1.80E-06 5.745465672 0.07414631 LHT(ph)PMY(ph)FLLRNLAILDICFSS(ph)TTAPK ddPTM_HeLa_Curcumin_4h_R1 1 LHTPMYFLLRNLAILDICFSSTTAPK 26 1 Q8NGI4 Q8NGI4 OR4D11 Olfactory receptor 4D11 3 0 LHT(0.945)PMY(0.962)FLLRNLAILDICFS(0.258)S(0.735)T(0.051)T(0.049)APK 41.166 0.0085467 0 469.4 433.87 510.02 314.44 452.85 730.86 406.71 394.37 491.7 432.86 TRUE FALSE FALSE 432.2464947 471.3717895 528.9217899 313.1389306 447.4500595 579.2713975 418.121188 514.6115975 437.7617402 447.9018528 0.965047347 1.052399731 1.180887702 0.69912399 0.998991312 1.293299847 0.933510735 1.148938309 0.97736086 1 8.807038824 -5.489837757 24.98382313 0.981989774 1.112754066 0.183360619 0.138274398 857.9220703 648714.1475 0.018416568 0.041152274 3.24E-06 5.489837757 0.130764292 LHTDDELNWLDHGR ddPTM_HeLa_Curcumin_4h_R1 4 LHTDDELNWLDHGR 14 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 ;;; ;;; 219.89 1.31E-14 158400400 7787 7440.4 7817.7 8029.2 7583.8 9232.7 6934.4 6411.8 8537.9 7253.8 FALSE FALSE TRUE 7170.650733 8083.515022 8107.430839 7995.977298 7493.368138 7317.733946 7128.960601 8366.728304 7601.313731 7505.86901 0.955339178 1.076959245 1.080145527 1.065296675 0.99833452 0.974934939 0.949784841 1.114691489 1.012716012 1 12.8738034 -7.275629638 24.90610076 0.978910168 1.032651471 0.14501862 0.050531255 940.5814966 1650863.479 0.008903257 0.01020852 5.30E-08 7.275629638 0.053741303 LHTPMYVFLS(ph)HLAIVDMS(ph)YAS(ph)S(ph)TVPK ddPTM_HeLa_Curcumin_4h_R1 1 LHTPMYVFLSHLAIVDMSYASSTVPK 26 0 Q8NGT7 Q8NGT7 OR2A12 Olfactory receptor 2A12 4 0 LHT(0.05)PMY(0.04)VFLS(0.904)HLAIVDMS(0.553)Y(0.517)AS(0.646)S(0.646)T(0.645)VPK 44.258 0.0071927 0 741.54 631.69 674.35 599.18 838.16 853.12 612.53 486.08 724.56 841.91 TRUE FALSE FALSE 682.8463265 686.2904688 699.3420042 596.7007519 828.1654894 676.1732954 629.7159433 634.2835544 645.0775808 871.1663098 0.783830043 0.787783528 0.802765208 0.684944706 0.950639941 0.776170161 0.722842397 0.728085496 0.740475812 1 9.766804352 -9.272756662 0.54095634 1.043743476 0.77432705 0 0.105062147 0.735405542 0.298021257 0.103029671 0.016421038 5.34E-10 9.272756662 -0.269416426 LHVAILER ddPTM_HeLa_Curcumin_4h_R1 2 LHVAILER 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 107.9 0.0021786 21182000 7449.8 4769.5 6217.9 5407.1 6746.3 7542.6 7155.8 5580.7 6111.2 6263.4 FALSE FALSE TRUE 6860.140469 5181.754328 6448.340844 5384.726853 6665.854779 5978.179737 7356.572489 7282.22974 5440.816649 6481.052684 1.058491699 0.799523562 0.994952696 0.830841395 1.02851421 0.922408755 1.135089136 1.123618353 0.839495822 1 12.66201245 -4.744811031 24.86282461 0.989917935 1.129353874 0.27521694 0.097531789 228.465001 341596.3861 0.01246179 0.046357211 1.80E-05 4.744811031 0.139435939 LHVGNIS(ph)PTCTNK ddPTM_HeLa_Curcumin_4h_R1 1 LHVGNISPTCTNK 13 0 E9PB51;Q9BWF3;D6R9K7;J3QRR5;Q9BWF3-3;Q9BWF3-4;Q9BWF3-2 E9PB51 RBM4 RNA-binding protein 4 1 0 LHVGNIS(0.958)PT(0.042)CTNK 115.58 0.0013769 170160000 7611.8 5462.3 6175.5 6939.9 5950.8 8372.9 6445.7 5732.2 7025.3 5552.9 TRUE FALSE FALSE 7009.317998 5934.436872 6404.369463 6911.184533 5879.840597 6636.266158 6626.548994 7479.921392 6254.642166 5745.862862 1.219889539 1.032819094 1.114605346 1.202810561 1.023317252 1.154964244 1.153273086 1.301792537 1.088547067 1 12.48830784 -9.511913943 1.208916946 0.998356067 1.151773363 0.181501376 0.082786245 0.445726392 1.145621448 0.057810081 0.01332746 3.08E-10 9.511913943 0.153417296 LHVGNISPT(ph)CTNK ddPTM_HeLa_Curcumin_4h_R1 1 LHVGNISPTCTNK 13 0 E9PB51;Q9BWF3;D6R9K7;J3QRR5;Q9BWF3-3;Q9BWF3-4;Q9BWF3-2 E9PB51 RBM4 RNA-binding protein 4 1 0 LHVGNIS(0.28)PT(0.705)CT(0.015)NK 115.8 0.0083891 75847000 2614.6 1697.9 2133.3 1970.3 1608.8 2316.5 2036.6 1492.9 2343.7 1883.2 TRUE FALSE FALSE 2407.651651 1844.65891 2212.361975 1962.147421 1589.616111 1836.031788 2093.741515 1948.078338 2086.601974 1948.64106 1.235554203 0.946638634 1.135335809 1.006931169 0.815756243 0.942211383 1.074462382 0.999711223 1.070798526 1 10.92825265 -6.086933758 5.345738941 1.100266955 0.959203755 0.245452381 0.094904776 0.243189954 11.38094765 0.017435767 0.029392663 8.19E-07 6.086933758 -0.1410632 LHYCVSCAIHSK ddPTM_HeLa_Curcumin_4h_R1 1 LHYCVSCAIHSK 12 0 Q5JNZ5;P62854 Q5JNZ5 RPS26P11;RPS26 Putative 40S ribosomal protein S26-like 1;40S ribosomal protein S26 0 0 74.962 0.011367 2097200 2086.1 1576.3 1699.6 1652.6 2064.1 3053.7 1680.1 1637.7 2262.5 2041 FALSE FALSE TRUE 1920.982984 1712.548348 1762.588671 1645.761979 2039.486956 2420.328198 1727.239084 2137.027191 2014.30941 2111.924598 0.909588811 0.810894645 0.834588826 0.779271183 0.965700649 1.146029645 0.817850735 1.011886122 0.953779038 1 11.04434261 -3.899758297 19.24608843 0.932287521 7.776293693 0.046077153 0.106374467 954.4052158 184126.2772 0.014973753 1378.87298 0.000125963 3.899758297 6.844006172 LIAMK(ac)TEK ddPTM_HeLa_Curcumin_4h_R1 1 LIAMKTEK 8 1 E7EWM1;Q15596 E7EWM1 NCOA2 Nuclear receptor coactivator 2 0 1 LIAMK(1)TEK 95.358 0.017351 2390200 2170.2 1734.6 2146.1 2005 2670.9 2623.7 1983.1 1018.4 1920.3 1520.1 FALSE TRUE FALSE 1998.42638 1884.531095 2225.636354 1996.703841 2639.051262 2079.515045 2038.740449 1328.905472 1709.647894 1572.923362 1.270517324 1.198107384 1.414968083 1.269422204 1.677800283 1.322070163 1.296147351 0.844863459 1.086923836 1 10.61923266 -8.859762308 0.633643542 0.988683386 1.309570091 0.192381621 0.195418378 0.915408657 0.664959588 0.153904465 0.045327231 1.38E-09 8.859762308 0.320886705 LIAPVAEEEATVPNNK ddPTM_HeLa_Curcumin_4h_R1 2 LIAPVAEEEATVPNNK 16 0 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;C9J7H8;F5H793 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain;L-lactate dehydrogenase 0 0 ; ; 341.51 2.70E-203 9594800 4112.6 4379.1 4224.2 4394.2 5275.2 6127.8 5189 4944.8 6509.7 4070.5 FALSE FALSE TRUE 3787.08337 4757.609891 4380.752568 4376.017965 5212.296685 4856.825205 5334.589375 6452.446757 5795.602196 4211.949572 0.899128374 1.129550535 1.040077165 1.038953076 1.237502158 1.153106209 1.266536857 1.531938274 1.375990405 1 12.04027245 -1.000000006 0.343373008 0.951872624 7.300763934 0.313339957 0.149497063 14.52736933 0.182891282 0.022735346 60.12754006 0.099999999 1.000000006 6.348891311 LIDFLECGK ddPTM_HeLa_Curcumin_4h_R1 1 LIDFLECGK 9 0 P17844-2;P17844;J3KTA4;J3KRZ1;J3QSF1 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 0 114.89 0.0020242 602170 598.78 422.88 433.21 550.16 457.73 450.69 486.41 360.64 411.66 204.06 FALSE FALSE TRUE 551.3859312 459.4318629 449.2651437 547.8835837 452.2718687 357.2118137 500.0573555 470.5974758 366.5019279 211.1510698 2.611333827 2.175844353 2.127695323 2.594746899 2.141935009 1.691735751 2.36824448 2.22872409 1.735733228 1 7.722131746 -9.383470654 1.038187734 0.97935814 2.25942841 0.485368389 0.328893626 0.207175112 0.389151083 0.199376089 0.048002768 4.14E-10 9.383470654 1.28007027 LIDFLESGK ddPTM_HeLa_Curcumin_4h_R1 1 LIDFLESGK 9 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 0 110.87 0.0033371 490320 290.78 315.35 327.08 191.88 339.52 337.55 227.46 323.49 245.3 288.03 FALSE FALSE TRUE 267.7644562 342.6074488 339.2018725 191.0860514 335.4714457 267.538325 233.8419154 422.1206118 218.3912037 298.0390211 0.898420801 1.149538901 1.138112289 0.641144407 1.125595717 0.897662071 0.784601676 1.416326662 0.732760438 1 8.219357419 -4.247670559 24.5774951 0.955559885 1.416327052 0.419820644 0.169168792 1266.865709 2261321.257 0.019737428 0.523281142 5.65E-05 4.247670559 0.460767167 LIDLES(ph)PTPESQK ddPTM_HeLa_Curcumin_4h_R1 2 LIDLESPTPESQK 13 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 LIDLES(0.988)PT(0.012)PESQK;LIDLES(0.871)PT(0.129)PESQK ; 234.52 6.81E-20 339940000 18127.3 14123.7 15342.8 16240.9 14951.8 17547.6 17105.8 15709.5 16473.3 13498.4 TRUE FALSE FALSE 16692.50508 15344.48969 15911.41766 16173.69946 14773.50955 13908.02996 17585.74271 20499.25423 14666.2202 13967.4684 1.195098826 1.098587751 1.139176923 1.157954971 1.057708465 0.995744509 1.259050116 1.467642786 1.050027091 1 13.76978294 -4.458633727 3.307976906 1.095045607 1.460506832 0.777851733 0.063555528 0.116816671 2.280051056 0.011430671 0.081870802 3.48E-05 4.458633727 0.365461225 LIDLESPT(ph)PESQK ddPTM_HeLa_Curcumin_4h_R1 1 LIDLESPTPESQK 13 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 LIDLES(0.155)PT(0.845)PESQK 142.39 0.0025745 10306000 4410.6 3464.9 3985 3591.5 3903.3 4541.3 4758.2 4049.6 5032.3 4318.1 TRUE FALSE FALSE 4061.496356 3764.390517 4132.687606 3576.639325 3856.755697 3599.383189 4891.702286 5284.304398 4480.26928 4468.153654 0.90898762 0.842493524 0.924920655 0.800473664 0.863165414 0.805563879 1.094792763 1.182659507 1.002711551 1 12.12546308 -4.592748678 5.927804826 0.91993095 1.162264712 0.649641836 0.071140579 0.098165479 6.013935386 0.011287206 0.044209403 2.55E-05 4.592748678 0.242333762 LIDLHSPS(ph)EIVK ddPTM_HeLa_Curcumin_4h_R1 1 LIDLHSPSEIVK 12 0 P60866;P60866-2;G3XAN0 P60866 RPS20 40S ribosomal protein S20 1 0 LIDLHS(0.003)PS(0.997)EIVK 67.326 0.019192 10020000 7197.8 6104.9 6370.9 6758.2 6207.2 8040.9 5764.7 4706.8 7527.6 6468.5 TRUE FALSE FALSE 6628.086535 6632.580353 6607.011158 6730.236359 6133.183194 6373.1267 5926.441967 6141.881653 6701.841113 6693.279894 0.990259879 0.990931271 0.987111142 1.005521428 0.916319546 0.952167966 0.885431666 0.917619127 1.001279077 1 12.70849763 -5.757368403 24.99884117 0.994862746 0.91801531 0.853203862 0.01583992 27.01117511 165866.452 0.002192998 0.004260965 1.75E-06 5.757368403 -0.076847437 LIDLHSPSEIVK ddPTM_HeLa_Curcumin_4h_R1 2 LIDLHSPSEIVK 12 0 P60866;P60866-2;G3XAN0 P60866 RPS20 40S ribosomal protein S20 0 0 ; ; 109.24 0.0010359 9802700 8132.2 5312.6 6970 6298.9 7224 9019.4 7470.6 6622 7112.4 6838.6 FALSE FALSE TRUE 7488.527789 5771.797472 7228.314331 6272.836821 7137.858518 7148.67477 7680.20493 8641.017316 6332.187514 7076.240841 1.058263555 0.815658709 1.021490717 0.886464574 1.008707685 1.010236216 1.08535098 1.221131037 0.894851893 1 12.78876744 -4.336091129 1.821985546 0.999528339 1.272886705 0.478431964 0.078499983 0.508636354 1.909947698 0.010689413 0.224883158 4.61E-05 4.336091129 0.273358366 LIEDTEDWRPR ddPTM_HeLa_Curcumin_4h_R1 2 LIEDTEDWRPR 11 1 Q96HC4;Q96HC4-7;Q96HC4-4;H0Y8Y3;H0YBI4;Q96HC4-3;Q96HC4-2;Q96HC4-6 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 0 0 ; ; 120.27 0.0035906 125145000 7003 5538.5 6232.5 5944.8 5816.3 8194 6151.9 5800.5 7781.1 6494.8 FALSE FALSE TRUE 6448.70516 6017.223261 6463.481933 5920.201993 5746.944421 6494.472035 6324.505757 7569.045748 6927.532797 6720.493817 0.959558231 0.895354333 0.961756994 0.880917706 0.855137223 0.966368278 0.941077535 1.12626333 1.030807108 1 12.71435153 -8.315114635 1.071872695 0.993212594 0.942345921 0.10532699 0.070819563 0.84615106 2.006431825 0.020931798 0.014120967 4.84E-09 8.315114635 -0.050866673 LIEGGAHIYVCGDAR ddPTM_HeLa_Curcumin_4h_R1 1 LIEGGAHIYVCGDAR 15 0 E7EMD0;P16435 E7EMD0 POR NADPH--cytochrome P450 reductase 0 0 154.01 0.0033753 5015500 1490.9 1347.7 1320.5 1382.5 1472.1 1666 1532.4 1226 1629.9 1105.7 FALSE FALSE TRUE 1372.893692 1464.189183 1369.438892 1376.779581 1454.546169 1320.45282 1575.39502 1599.801756 1451.104048 1144.122993 1.19995289 1.279748062 1.196933285 1.203349282 1.27131976 1.154117895 1.376945512 1.398277778 1.268311237 1 10.16002643 -13.52287875 0.081662474 0.077119591 1.537184838 0.095235369 0.102748576 62.29845308 0.389658367 10.33089308 1.095629973 3.00E-14 13.52287875 1.460065248 LIEILSEK ddPTM_HeLa_Curcumin_4h_R1 1 LIEILSEK 8 0 A0A087WVV2;Q9P2E9-3;Q9P2E9;F8W7S5 A0A087WVV2 RRBP1 Ribosome-binding protein 1 0 0 98.997 0.0098904 0 0 0 209.65 144.07 183.37 301.25 0 0 0 0 FALSE FALSE TRUE 0 0 217.4198134 143.4738765 181.1834325 238.7673542 0 0 0 0 0 LIELQAGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 LIELQAGKK 9 1 K7ELL7;P14314-2;P14314;K7EPW7 K7ELL7 PRKCSH Glucosidase 2 subunit beta 0 1 LIELQAGK(1)K 91.867 0.0062439 1177500 550.19 534.47 528.52 652.78 486.17 488.06 345.56 440.55 815.3 676.92 FALSE TRUE FALSE 506.6418809 580.6672052 548.1074161 650.0789693 480.3727403 386.8308544 355.2554836 574.871667 725.8636298 700.4429196 0.723316443 0.829000036 0.782515464 0.928096996 0.685812829 0.552266064 0.507186915 0.82072593 1.036292337 1 9.452123677 -13.52287875 0.117588428 1.949339784 0.555980955 0.536464027 0.113524601 62.31880543 0.53147301 14.17189974 0.608938524 3.00E-14 13.52287875 -1.393358829 AQS(ph)PGAVEEILDRENKR ddPTM_HeLa_Curcumin_4h_R1 1 AQSPGAVEEILDRENKR 17 2 H7BXT7;E9PHY4;A0A0C4DH16;B8ZZS0;Q9NYM9 H7BXT7 BET1L BET1-like protein 1 0 AQS(1)PGAVEEILDRENKR 52.853 0.014043 8718500 2821.5 2336.3 2505.3 2769.8 1928.4 2660.8 1555.5 743.17 3793.3 2976 TRUE FALSE FALSE 2598.175298 2538.239362 2598.148622 2758.339302 1905.405089 2108.920087 1599.143144 969.7591119 3377.18448 3079.415778 0.843723448 0.824260036 0.843714785 0.895734613 0.618755383 0.684844217 0.519300822 0.314916589 1.096696492 1 11.58844096 -4.375989577 0.416504441 0.942400306 1.08E-18 0.864095286 0.081520859 1.14955157 0.143703079 0.018959047 0.527397729 4.21E-05 4.375989577 -0.942400306 down LIEVDDER ddPTM_HeLa_Curcumin_4h_R1 3 LIEVDDER 8 0 P62753;A2A3R7 P62753 RPS6 40S ribosomal protein S6 0 0 ;; ;; 166.68 0.0058372 374464300 19608.1 16700.3 16554.2 18106.1 17031.7 20721.1 16114.2 15541.8 19202.8 16964.8 FALSE FALSE TRUE 18056.09819 18143.79952 17167.71321 18031.18176 16828.6081 16423.31029 16566.32108 20280.42327 17096.30088 17554.32554 1.02858399 1.033579985 0.977976236 1.027164599 0.958658768 0.935570566 0.943717322 1.155294929 0.97390816 1 14.09953895 -6.757381232 24.9974127 1.015381294 0.993648116 0 0.060869619 354.0573916 2180904.776 0.009030516 0.012516704 1.75E-07 6.757381232 -0.021733178 LIFAK(ac)PINSK ddPTM_HeLa_Curcumin_4h_R1 2 LIFAKPINSK 10 1 Q6MZP7;Q6MZP7-3;D6REW4 Q6MZP7 LIN54 Protein lin-54 homolog 0 1 ; LIFAK(1)PINSK;LIFAK(1)PINSK 103.26 0.0076245 3377800 4230.1 2624.9 3697.7 4280.3 3411.4 2343.52 2400.1 1819.44 3674.7 3134.8 FALSE TRUE FALSE 3895.283121 2851.78466 3834.740015 4262.589253 3370.721283 1857.447535 2467.440346 2374.17888 3271.594604 3243.734067 1.200863894 0.879167219 1.18219926 1.314099481 1.039148467 0.57262633 0.760678988 0.73192772 1.008589032 1 11.66343983 -5.354618947 5.68858621 1.102466056 0.697224084 0.689524656 0.123410171 0.098418661 4.802305567 0.018504886 0.042021604 4.42E-06 5.354618947 -0.405241972 LIFRLS(ph)S(ph)SS(ph)GVRATLR ddPTM_HeLa_Curcumin_4h_R1 1 LIFRLSSSSGVRATLR 16 2 Q15124 Q15124 PGM5 Phosphoglucomutase-like protein 5 3 0 LIFRLS(0.932)S(0.849)S(0.554)S(0.665)GVRATLR 77.24 0.011282 5754100 1433.7 965.83 834.85 1116.8 1273.1 1422.1 1085 825.73 1433.9 1133.3 TRUE FALSE FALSE 1320.221132 1049.312042 865.7902754 1112.178978 1257.919114 1127.14043 1115.44218 1077.491276 1276.604757 1172.682091 1.125813332 0.89479668 0.738299222 0.94840621 1.072685533 0.961164529 0.951188893 0.91882641 1.088619642 1 10.19559624 -7.252442723 24.93238255 1.059411852 0.927994107 0.387904635 0.083037841 584.5599444 1619988.67 0.015756667 0.019145625 5.59E-08 7.252442723 -0.131417745 LIGEPDLVVSVIPNNS(ph)NENIPR ddPTM_HeLa_Curcumin_4h_R1 2 LIGEPDLVVSVIPNNSNENIPR 22 0 A0A0A0MSU3;Q9H9A7 A0A0A0MSU3 RMI1 RecQ-mediated genome instability protein 1 1 0 LIGEPDLVVS(0.006)VIPNNS(0.994)NENIPR;LIGEPDLVVSVIPNNS(1)NENIPR ; 136.26 4.64E-06 16033500 5824 4641.68 4662.01 5314.8 4908 7397.1 4505.28 2432.28 5693.7 4206.24 TRUE FALSE FALSE 5363.024255 5042.886136 4834.788192 5292.808766 4849.475306 5862.858078 4631.686031 3173.870975 5069.115355 4352.406527 1.232197457 1.158643179 1.110831022 1.21606489 1.114205503 1.347038251 1.064166686 0.729222088 1.164669551 1 12.0875976 -4.292510992 4.057169563 1.137837418 0.704869047 0.670606889 0.090162893 0.116978982 3.915404396 0.015209691 0.138367421 5.10E-05 4.292510992 -0.432968371 LIGTAVPQRTS(ph)PTGPK ddPTM_HeLa_Curcumin_4h_R1 2 LIGTAVPQRTSPTGPK 16 1 C9JB30;Q9UPY8 C9JB30 MAPRE3 Microtubule-associated protein RP/EB family member 3 1 0 LIGTAVPQRT(0.227)S(0.739)PT(0.034)GPK;LIGT(0.001)AVPQRT(0.232)S(0.759)PT(0.009)GPK ; 149.31 0.0033742 87781000 5387.2 3937.2 3882.7 4467 3136.4 5330.4 3720.7 3610.5 5322 4211.3 TRUE FALSE FALSE 4960.797435 4277.514024 4026.596278 4448.516738 3099.000478 4224.814954 3825.092828 4711.324829 4738.189915 4357.642362 1.138413166 0.981611998 0.924030919 1.020854023 0.711164483 0.969518516 0.877789527 1.081163721 1.087328771 1 12.08933208 -7.019166609 4.713635981 1.065480739 0.925532043 0.305330011 0.096795555 0.183952306 10.61152203 0.01637033 0.020796709 9.57E-08 7.019166609 -0.139948696 LIHEQEQQS(ph)SS ddPTM_HeLa_Curcumin_4h_R1 1 LIHEQEQQSSS 11 0 Q96FQ6 Q96FQ6 S100A16 Protein S100-A16 1 0 LIHEQEQQS(0.937)S(0.037)S(0.026) 94.82 0.014251 20591000 2365.5 1664.1 1832.9 1970.1 2218.5 2498 2232.6 2373.1 2436.7 2349.3 TRUE FALSE FALSE 2178.268179 1807.937389 1900.828886 1961.948248 2192.045836 1979.886642 2295.240747 3096.647266 2169.400106 2430.938 0.896060771 0.743720074 0.781932277 0.807074573 0.901728401 0.814453779 0.944179056 1.273848722 0.892412767 1 11.24729738 -4.271345561 4.142394973 0.901331718 1.301326979 0.681579937 0.080951203 0.125414676 4.711265047 0.01423333 0.146422178 5.35E-05 4.271345561 0.399995261 LIHGEDS(ph)DS(ph)EGEEEGR ddPTM_HeLa_Curcumin_4h_R1 2 LIHGEDSDSEGEEEGR 16 0 Q9C0C9 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 2 0 LIHGEDS(1)DS(1)EGEEEGR;LIHGEDS(1)DS(1)EGEEEGR ; 151.07 0.00082352 55978000 5364.3 4495.8 5296.1 4785.5 6263.9 5575.5 3882.45 4305 4309.39 4368.7 TRUE FALSE FALSE 4939.709995 4884.396919 5492.378125 4765.698869 6189.207084 4419.078451 3991.381098 5617.574682 3836.660699 4520.512 1.092732415 1.080496395 1.214990277 1.054238739 1.369138514 0.977561491 0.8829489 1.242685493 0.8487226 1 12.14227047 -8.67628586 0.750675457 1.003669762 1.111938329 0.183949728 0.139419883 1.212058538 1.357081882 0.06852916 0.028027777 2.11E-09 8.67628586 0.108268568 LIHPDEDISLEER ddPTM_HeLa_Curcumin_4h_R1 4 LIHPDEDISLEER 13 0 J3KS31;J3QRS9;X6R4W8;O43670-3;O43670-2;O43670;O43670-4 J3KS31 ZNF207 BUB3-interacting and GLEBS motif-containing protein ZNF207 0 0 ;;; ;;; 204.32 5.11E-09 68409000 18394.9 15755.5 16134.9 17407.8 17545.9 20186.6 16912.9 15540.6 19002.1 17131.5 FALSE FALSE TRUE 16938.92425 17117.33521 16732.87359 17335.77114 17336.6766 15999.67161 17387.43046 20278.8574 16917.61717 17726.81835 0.955553553 0.965618019 0.943929884 0.977940361 0.97799144 0.902568712 0.980854551 1.143964867 0.954351584 1 14.113646 -4.266026236 5.384999381 0.96998552 1.150308636 0.813035871 0.025962226 0.051568721 5.466534168 0.003960304 0.034114543 5.42E-05 4.266026236 0.180323115 LIHPDEDISLEERR ddPTM_HeLa_Curcumin_4h_R1 2 LIHPDEDISLEERR 14 1 J3KS31;J3QRS9;X6R4W8;O43670-3;O43670-2;O43670;O43670-4 J3KS31 ZNF207 BUB3-interacting and GLEBS motif-containing protein ZNF207 0 0 ; ; 142.76 0.00020213 20514400 4241.2 3328.4 3121.1 3433.6 2823.2 4826.3 3257 3316 4850.8 4068.7 FALSE FALSE TRUE 3905.504545 3616.092065 3236.770712 3419.392673 2789.535184 3825.270976 3348.382654 4327.033135 4318.679376 4210.087022 0.927654114 0.858911478 0.768813256 0.812190497 0.662583735 0.908596653 0.795323858 1.0277776 1.025793375 1 12.03963434 -7.455893036 1.47527522 0.9756248 0.822569871 0.371420139 0.091231506 0.291190693 1.244304714 0.017607741 0.019300914 3.50E-08 7.455893036 -0.15305493 LIHTLDDR ddPTM_HeLa_Curcumin_4h_R1 2 LIHTLDDR 8 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;H7C3A1 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 0 0 ; ; 174.16 0.00084187 17919400 8122.1 5540.6 7468.3 6155.4 6625.1 8845.5 7167.5 6810 7239.3 7296.1 FALSE FALSE TRUE 7479.227215 6019.504776 7745.081768 6129.930586 6546.100009 7010.843591 7368.60076 8886.337651 6445.166902 7549.638932 0.990673499 0.797323532 1.025887706 0.811950166 0.86707458 0.928632966 0.976020287 1.177054655 0.853705318 1 12.88219193 -4.265032477 4.38036078 0.957454351 1.1921105 0.384871557 0.086131878 0.168189898 7.76563465 0.011829574 0.121512396 5.43E-05 4.265032477 0.234656149 LIIESPS(ph)NT(ph)SSTEPA ddPTM_HeLa_Curcumin_4h_R1 1 LIIESPSNTSSTEPA 15 0 P38432 P38432 COIL Coilin 2 0 LIIES(0.036)PS(0.964)NT(0.906)S(0.056)S(0.033)T(0.004)EPA 111.12 0.0095061 9877600 1438.9 1067.6 1283.5 1386.3 908 1474.3 1355.2 360.39 1405.5 1183 TRUE FALSE FALSE 1325.009547 1159.878587 1331.067639 1380.563858 897.172693 1168.513561 1393.223265 470.271252 1251.320166 1224.109162 1.082427604 0.94752872 1.087376584 1.127811065 0.732918861 0.954582808 1.138152796 0.384174277 1.02222923 1 10.2575165 -4.255016911 24.99721422 1.021650458 0.384173991 0.735194285 0.112553897 276.9848331 1078037.48 0.015230779 0.192892712 5.56E-05 4.255016911 -0.637476468 SLSNS(ph)NPDISGTPTSPDDEVR ddPTM_HeLa_Curcumin_4h_R1 3 SLSNSNPDISGTPTSPDDEVR 21 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 SLSNS(0.973)NPDIS(0.021)GT(0.005)PTSPDDEVR;S(0.001)LS(0.371)NS(0.628)NPDISGTPTSPDDEVR;SLSNS(0.998)NPDIS(0.001)GTPTSPDDEVR ;; 320.13 4.13E-120 289901000 5653.99 5089.63 5344.84 5346.83 5716 5702.5 3478.11 794.224 6372.3 5313 TRUE FALSE FALSE 5206.470725 5529.554938 5542.924472 5324.706234 5647.840433 4519.73722 3575.696406 1036.379241 5673.274633 5497.626355 0.947039757 1.005807703 1.008239577 0.968546404 1.027323443 0.82212521 0.650407317 0.188513947 1.031949839 1 12.42459314 -4.374337833 1.42633268 0.981618705 1.27E-18 0.975946185 0.039105707 0.095896047 0.202562629 0.005391734 0.125621756 4.22E-05 4.374337833 -0.981618705 down LIIESPSNTS(ph)STEPA ddPTM_HeLa_Curcumin_4h_R1 1 LIIESPSNTSSTEPA 15 0 P38432 P38432 COIL Coilin 1 0 LIIESPS(0.001)NT(0.05)S(0.679)S(0.05)T(0.221)EPA 139.89 0.00054121 5852000 2865.8 2737.9 2579.8 2770.8 2681.2 3797.9 3260.8 431.69 3135.5 3140.5 TRUE FALSE FALSE 2638.968906 2974.551876 2675.409657 2759.335164 2649.228441 3010.172729 3352.289272 563.3102937 2791.543495 3249.632141 0.81208235 0.915350337 0.823296158 0.849122314 0.815239487 0.92631184 1.031590385 0.173345865 0.859033692 1 11.6660607 -4.255105964 24.99921198 0.900492235 0.173345541 0.896993147 0.07305972 189.7557725 748982.2384 0.012096049 0.152137011 5.56E-05 4.255105964 -0.727146694 LIIESPSNTSS(ph)TEPA ddPTM_HeLa_Curcumin_4h_R1 1 LIIESPSNTSSTEPA 15 0 P38432 P38432 COIL Coilin 1 0 LIIESPSNT(0.013)S(0.245)S(0.738)T(0.005)EPA 153.75 0.00039973 3389600 2416.7 1933 2078.7 2212.7 2213.4 2821.1 2480.7 412.35 2528.5 2458.2 TRUE FALSE FALSE 2225.415645 2100.079907 2155.738451 2203.544434 2187.006651 2235.97206 2550.301766 538.0736168 2251.129876 2543.622267 0.874900206 0.825625697 0.847507304 0.866301755 0.859800089 0.879050356 1.002625979 0.211538334 0.885009502 1 11.31266873 -4.257059947 24.99970221 0.914487044 0.211538055 0.919130478 0.060388639 103.5135521 590878.4339 0.010340318 0.108932226 5.53E-05 4.257059947 -0.702948989 LIITPET(ph)PEPEAQPVGPPSR ddPTM_HeLa_Curcumin_4h_R1 1 LIITPETPEPEAQPVGPPSR 20 0 Q96DU7 Q96DU7 ITPKC Inositol-trisphosphate 3-kinase C 1 0 LIIT(0.001)PET(0.996)PEPEAQPVGPPS(0.003)R 89.913 0.0035069 4150500 1456.1 806.2 971.15 1189.4 956.9 1228.2 1034.6 2104.3 1030 966.25 TRUE FALSE FALSE 1340.848149 875.8843356 1007.141673 1184.478578 945.4895925 973.4574753 1063.628092 2745.891383 917.0115769 999.8271156 1.34108 0.876035789 1.007315823 1.184683391 0.945653081 0.9736258 1.063812008 2.746366187 0.917170141 1 9.965534844 -4.260574226 24.99134882 1.104668845 2.746366703 0.923678714 0.146383807 16.0264914 462873.0574 0.02325293 0.188329167 5.49E-05 4.260574226 1.641697857 LIKEFS(ph)IY(ph)MT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 LIKEFSIYMTK 11 1 P00505-2;P00505 P00505-2 GOT2 "Aspartate aminotransferase, mitochondrial" 3 0 LIKEFS(1)IY(1)MT(1)K 53.448 0.0095946 0 1365.7 1174.4 1475.1 1326.7 1648.2 1905.2 1097.3 636.01 1707.2 1512.7 TRUE FALSE FALSE 1257.603404 1275.909903 1529.768504 1321.210467 1628.546291 1510.040044 1128.087285 829.9265212 1519.924431 1565.266212 0.803443781 0.815139235 0.977321616 0.844080359 1.040427678 0.964717715 0.720699952 0.530214295 0.971032543 1 10.61219233 -4.510513857 3.134431665 0.911577759 0.541629063 0.718691484 0.07909505 0.127536804 2.361215912 0.013148792 0.085549756 3.09E-05 4.510513857 -0.369948695 LILGLMMPPAHYDAK ddPTM_HeLa_Curcumin_4h_R1 1 LILGLMMPPAHYDAK 15 0 E7EMC6;E5RK69;P08133-2;P08133 E7EMC6 ANXA6 Annexin;Annexin A6 0 0 60.364 0.012271 0 299.2 400.38 409.21 352.6 457.21 779.59 378.54 355.08 392.01 450.04 FALSE FALSE TRUE 275.5180043 434.9870631 424.3756826 351.1410346 451.7580694 617.8942462 389.1608136 463.3422574 349.0074838 465.6788565 0.591648086 0.934092362 0.911305456 0.75404118 0.970106465 1.326867728 0.835684954 0.994982381 0.749459588 1 8.86319157 -5.58888663 6.001209366 0.819366261 1.049369128 0.3111869 0.155304803 0.22056023 14.76199366 0.027460293 0.055603607 2.58E-06 5.58888663 0.230002867 LILIESR ddPTM_HeLa_Curcumin_4h_R1 1 LILIESR 7 0 P62277 P62277 RPS13 40S ribosomal protein S13 0 0 103.29 0.018437 1979100 1812.8 1005.8 1728.6 1412.2 1607.2 1557 1279.5 1457.3 1293.2 1273.4 FALSE FALSE TRUE 1669.314967 1092.73687 1792.663437 1406.356691 1588.03519 1234.060649 1315.399326 1901.624061 1151.339195 1317.650555 1.266887462 0.829307031 1.360499891 1.067321442 1.20520208 0.9365614 0.998291483 1.443193003 0.873781892 1 10.3637521 -9.703023275 1.590886442 0.999960027 1.147801649 0.137105434 0.185109219 0.799931456 3.650127535 0.122709919 0.027018099 1.98E-10 9.703023275 0.147841623 LIMGIGHR ddPTM_HeLa_Curcumin_4h_R1 1 LIMGIGHR 8 0 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 0 0 79.116 0.012882 1690600 2113.2 1112.1 1533.4 1272.6 1654.2 1921.6 1755.8 1858.3 1367.8 1632.4 FALSE FALSE TRUE 1945.93799 1208.224969 1590.229153 1267.334318 1634.474745 1523.038499 1805.063023 2424.887115 1217.755762 1689.125778 1.152038537 0.715296033 0.941451 0.750290082 0.967645374 0.901672639 1.068637425 1.435587063 0.720938475 1 10.72206105 -4.280438957 3.646995514 0.998550261 1.475767477 0.418257404 0.160169567 0.194405255 4.730668941 0.021766105 0.243857578 5.24E-05 4.280438957 0.477217216 LINRPIIVFR ddPTM_HeLa_Curcumin_4h_R1 2 LINRPIIVFR 10 1 Q16658;C9JPH9;C9JFC0;A0A0A0MSB2 Q16658 FSCN1 Fascin 0 0 ; ; 146.79 5.33E-06 7028000 776.62 478.3 571.44 572.77 736.41 12415.6 3879.8 4047.3 820.64 873.1 FALSE FALSE TRUE 715.1497075 519.6421207 592.6180691 570.4000295 727.6287917 9840.464607 3988.656746 5281.303139 730.6178451 903.44016 0.791585031 0.57518156 0.65595719 0.631364483 0.805397882 10.89221516 4.414965066 5.845769728 0.808706406 1 9.819285236 -5.29112285 24.53241722 0.829129097 6.787381193 0.779242178 1.53394367 164.5651709 136007.4802 0.19741628 0.441501544 5.12E-06 5.29112285 5.958252095 LIPDGCGVK ddPTM_HeLa_Curcumin_4h_R1 1 LIPDGCGVK 9 0 F8W7C6;A0A087WV22;X1WI28;P27635 F8W7C6 RPL10 60S ribosomal protein L10 0 0 94.302 0.0099092 0 5262 4205.5 4763.1 4429.5 5072 5862.2 3447.7 4223.5 5030 5076.6 FALSE FALSE TRUE 4845.507148 4569.004681 4939.624676 4411.171903 5011.519713 4646.313639 3544.433183 5511.225707 4478.221584 5253.011472 0.922424627 0.869787684 0.940341498 0.839741532 0.95402794 0.884504758 0.674743088 1.049155468 0.852505579 1 12.35892902 -8.373706974 0.340406127 1.022194654 0.863702416 0 0.101618679 1.9971054 0.513601012 0.126400308 0.049892513 4.23E-09 8.373706974 -0.158492238 LIPDSIGK ddPTM_HeLa_Curcumin_4h_R1 2 LIPDSIGK 8 0 P61247;H0Y9Y4;D6RAT0;D6R9B6;D6RG13;D6RB09 P61247 RPS3A 40S ribosomal protein S3a 0 0 ; ; 110.31 0.0063299 8495200 13594.5 12184 13358.9 12287.8 14458.9 15310.1 12411 11449.6 12086.7 10980.9 FALSE FALSE TRUE 12518.48098 13237.13067 13853.99259 12236.95634 14286.48706 12134.61268 12759.21926 14940.53033 10760.81925 11362.48546 1.10173791 1.164985488 1.219274835 1.076961232 1.257338204 1.067954078 1.122925024 1.314899842 0.947048011 1 13.47199083 -8.21040479 0.456648588 0.989851926 1.181633382 0.517201405 0.075288978 0.669374511 0.320435949 0.054559894 0.026310853 6.16E-09 8.21040479 0.191781457 LIPGPLS(ph)PVAR ddPTM_HeLa_Curcumin_4h_R1 2 LIPGPLSPVAR 11 0 P48634;P48634-2;P48634-3 P48634 PRRC2A Protein PRRC2A 1 0 LIPGPLS(1)PVAR;LIPGPLS(1)PVAR ; 158.56 0.00037743 1166530000 12582.5 9924.8 10908.6 10352.7 9944.9 12902.4 12143.9 11397.9 12042.5 9993.6 TRUE FALSE FALSE 11586.58185 10782.65549 11312.88231 10309.86327 9826.313563 10226.2968 12484.62515 14873.06724 10721.46788 10340.87686 1.120464155 1.042721583 1.093996425 0.997000875 0.950239878 0.988919696 1.207308174 1.438279118 1.036804521 1 13.3360709 -4.426306303 2.799908815 1.044432367 1.450883777 0.859691683 0.051292325 0.107010825 1.359879625 0.008959294 0.081629025 3.75E-05 4.426306303 0.40645141 LIPITGGNARS(ph)PEDQLGK ddPTM_HeLa_Curcumin_4h_R1 2 LIPITGGNARSPEDQLGK 18 1 Q9UK61-3;Q9UK61;Q9UK61-2 Q9UK61-3 FAM208A Protein FAM208A 1 0 LIPITGGNARS(1)PEDQLGK;LIPIT(0.002)GGNARS(0.998)PEDQLGK ; 153.68 0.00057517 105621000 2265.5 1213.35 2057.85 1931.91 1631.16 2082.22 1479.29 1005.26 2291.9 1897.58 TRUE FALSE FALSE 2086.183284 1318.226567 2134.115731 1923.916268 1611.709482 1650.344101 1520.794896 1311.759146 2040.484304 1963.520764 1.062470702 0.671358608 1.086882182 0.979829857 0.820826299 0.840502495 0.774524479 0.66806482 1.039196703 1 10.93922714 -3.102053196 0.318694486 1.030025846 8.66E-11 0.459896562 0.111061565 8.496326249 0.349540636 0.040259034 3.934802388 0.000790582 3.102053196 -1.030025846 LIPNATGTGTFSPGAS(ph)PGSEAR ddPTM_HeLa_Curcumin_4h_R1 1 LIPNATGTGTFSPGASPGSEAR 22 0 Q16512;Q16512-2;K7EN76;Q16512-3 Q16512 PKN1 Serine/threonine-protein kinase N1 1 0 LIPNATGT(0.009)GT(0.032)FS(0.006)PGAS(0.716)PGS(0.236)EAR 139.69 8.37E-07 0 970.25 929.22 782.76 1006.5 749.23 1212.4 657.63 762.73 1186.9 911.88 TRUE FALSE FALSE 893.4536887 1009.537636 811.7697742 1002.33537 740.2959216 960.9345734 676.0813279 995.2828658 1056.700039 943.5677621 0.946888739 1.069915354 0.860319531 1.062282339 0.78457102 1.018405473 0.716515925 1.054808044 1.119898413 1 9.881982318 -5.769925538 24.99982588 0.978162156 0.889844478 0.162631965 0.11652985 250.7070073 738573.0499 0.013710366 0.025141275 1.70E-06 5.769925538 -0.088317678 LIQNLDANHDGR ddPTM_HeLa_Curcumin_4h_R1 2 LIQNLDANHDGR 12 0 Q96FQ6 Q96FQ6 S100A16 Protein S100-A16 0 0 ; ; 234.79 1.50E-19 14884800 9775.2 7031.8 8394.9 7811.2 9093.8 11849.1 8193.1 8082.4 7981.8 7145.5 FALSE FALSE TRUE 9001.482605 7639.597459 8706.022379 7778.879324 8985.362374 9391.463093 8422.976335 10546.68655 7106.216509 7393.805593 1.217435662 1.033242944 1.177475154 1.052080586 1.215255427 1.270179879 1.139193644 1.426421945 0.961104051 1 12.8521014 -1 0.022791645 7.33E-16 2.741203168 0.519734403 0.093473445 1565.1621 2.774070524 119.1864489 232.2000627 0.1 1 2.741203168 LIQTMMFVS(ph)EVK ddPTM_HeLa_Curcumin_4h_R1 1 LIQTMMFVSEVK 12 0 H0Y9C1;H0Y9Z5;Q96LI5-2;Q96LI5 H0Y9C1 CNOT6L CCR4-NOT transcription complex subunit 6-like 1 0 LIQT(0.004)MMFVS(0.996)EVK 67.879 0.017292 3448800 2444.3 1639.2 1722 1884.7 1777 2133.3 2022.7 1883.7 2397.4 1952.2 TRUE FALSE FALSE 2250.831076 1780.885144 1785.818835 1876.901611 1755.810436 1690.829533 2079.451518 2458.031459 2134.411218 2020.038805 1.114251405 0.881609373 0.884051747 0.929141364 0.869196389 0.837028244 1.029411669 1.216823881 1.056618919 1 10.98016729 -7.261451189 24.99999845 1.053952052 0.941946825 0.173466525 0.106404142 1.412508802 2987806.312 0.019070064 0.022552128 5.48E-08 7.261451189 -0.112005227 LIRDFQEY(ph)VEPGEDFPASPQR ddPTM_HeLa_Curcumin_4h_R1 1 LIRDFQEYVEPGEDFPASPQR 21 1 Q9Y6G9;C9JGM7 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 0 LIRDFQEY(0.55)VEPGEDFPAS(0.45)PQR 66.152 0.016317 3083600 1005.9 682.54 732.79 735.84 548.53 973.1 713.33 722.95 1333.7 854.75 TRUE FALSE FALSE 926.2819536 741.5357163 759.947842 732.7952891 541.989138 771.2680909 733.34412 943.3741269 1187.396447 884.4524989 1.047294179 0.838412144 0.859229685 0.828529842 0.612796209 0.872028845 0.829150374 1.066619325 1.342521445 1 9.788640852 -7.255878107 23.50121638 1.022333365 0.835462839 0.395796299 0.14444879 141.9909882 600034.8781 0.017022906 0.020518425 5.55E-08 7.255878107 -0.186870525 LIRDFQEYVEPGEDFPAS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 1 LIRDFQEYVEPGEDFPASPQR 21 1 Q9Y6G9;C9JGM7 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 0 LIRDFQEYVEPGEDFPAS(1)PQR 64.035 0.0029643 1891500 1034.5 961.82 1172.9 912.32 820.33 1120.8 852.98 566.39 1325 983.78 TRUE FALSE FALSE 952.6182334 1044.955435 1216.368706 908.5450616 810.5481005 888.333446 876.9123231 739.0797037 1179.650815 1017.966282 0.935805292 1.026512817 1.194900782 0.892509976 0.796242582 0.872655079 0.86143553 0.726035544 1.158830932 1 9.99147406 -6.006650825 24.70241325 0.991796948 0.824496804 0.567702073 0.093667324 171.7213129 637810.0371 0.012112242 0.021378298 9.85E-07 6.006650825 -0.167300144 LIRDFQEYVEPGEDFPAS(ph)PQRR ddPTM_HeLa_Curcumin_4h_R1 2 LIRDFQEYVEPGEDFPASPQRR 22 2 Q9Y6G9;C9JGM7 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 0 LIRDFQEYVEPGEDFPAS(1)PQRR;LIRDFQEYVEPGEDFPAS(1)PQRR ; 92.147 0.00020455 8994500 1779.01 1374.75 1256.94 1374.95 1088 1800.02 1303.49 1208.23 2374.91 1810.52 TRUE FALSE FALSE 1638.199481 1493.577264 1303.523302 1369.260821 1075.026311 1426.675562 1340.062421 1576.613765 2114.388315 1873.435435 0.87443605 0.797239785 0.695793022 0.730882311 0.573826186 0.761529079 0.715296826 0.841562904 1.128615524 1 10.87147054 -7.524075465 0.883478691 0.970003478 0.712386077 0.697881388 0.083230112 0.193077073 0.312061897 0.017055948 0.017475131 2.99E-08 7.524075465 -0.257617401 LIRGPGENGDDS(ph) ddPTM_HeLa_Curcumin_4h_R1 1 LIRGPGENGDDS 12 1 Q6IBS0 Q6IBS0 TWF2 Twinfilin-2 1 0 LIRGPGENGDDS(1) 161.87 0.0016573 45816000 4688.6 3519.7 3317.8 3318.3 2645.9 4375.5 2957 2449.5 5193.9 4375 TRUE FALSE FALSE 4317.492363 3823.927185 3440.760587 3304.569754 2614.349371 3467.971978 3039.965462 3196.341274 4624.142164 4527.030924 0.95371391 0.844687666 0.760047953 0.729964034 0.577497573 0.766058822 0.671514181 0.706056868 1.02145142 1 12.14434945 -6.921182746 1.232018863 0.984495125 0.684591769 0.88699708 0.047189848 0.087344417 0.261923313 0.008274565 0.011494409 1.20E-07 6.921182746 -0.299903356 LIRPEYAWIVQPVSGAVYDRPGAS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 LIRPEYAWIVQPVSGAVYDRPGASPK 26 2 G3V198;Q12769 G3V198 NUP160 Nuclear pore complex protein Nup160 1 0 LIRPEYAWIVQPVSGAVYDRPGAS(1)PK;LIRPEYAWIVQPVS(0.006)GAVY(0.044)DRPGAS(0.95)PK ; 125.95 2.11E-08 309098000 2269.19 2087.58 2235.59 1776.11 1862.6 6009.75 3953.69 2762 2393.48 2332.25 TRUE FALSE FALSE 2089.581217 2268.021113 2318.442932 1768.760927 1840.389712 4763.260106 4064.619901 3604.121085 2130.921232 2413.295514 0.86586214 0.939802482 0.960695828 0.732923472 0.762604373 1.973757494 1.68426116 1.493443743 0.882992249 1 11.23678887 -5.266270662 24.99720615 0.91167343 1.713864848 0.888253119 0.13605023 93.88252769 485752.1765 0.019918671 0.045920869 5.42E-06 5.266270662 0.802191417 LIS(ph)PLASPADGVK ddPTM_HeLa_Curcumin_4h_R1 1 LISPLASPADGVK 13 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 0 LIS(0.874)PLAS(0.126)PADGVK 83.53 0.018695 14875000 974.37 574.83 751.1 773.6 781.35 908.7 586.13 249.93 891.08 1083.9 TRUE FALSE FALSE 897.2475863 624.5157438 778.9364267 770.3990482 772.0329116 720.2253768 602.5752303 326.1325065 793.3307534 1121.565444 0.799995748 0.556825058 0.694508226 0.686896206 0.688352976 0.642160812 0.537262657 0.290783305 0.707342365 1 10.13129809 -5.594975535 0.132119903 1.21528024 3.11E-14 0.464385894 0.127289465 5.698897378 0.222477958 0.570342716 1.541492202 2.54E-06 5.594975535 -1.21528024 LIS(ph)WYDNEFGYSNR ddPTM_HeLa_Curcumin_4h_R1 2 LISWYDNEFGYSNR 14 0 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 0 LIS(1)WYDNEFGYSNR;LIS(1)WYDNEFGYSNR ; 186.29 4.00E-05 15887100 2618.9 2437 2297.55 2654.7 2334.14 2708.1 2340.04 1359.21 2715.3 2371.55 TRUE FALSE FALSE 2411.611302 2647.643421 2382.699224 2643.715555 2306.306905 2146.409533 2405.695225 1773.626872 2417.438383 2453.961186 0.982742235 1.078926364 0.970960436 1.077325742 0.93983023 0.874671346 0.980331408 0.722760768 0.985116797 1 11.26089671 -3.433856113 0.852583424 0.99917242 3.93E-12 0.66960121 0.056067508 3.477696593 0.6689833 0.00822112 4.575130795 0.000368251 3.433856113 -0.99917242 LISDS(ph)VER ddPTM_HeLa_Curcumin_4h_R1 2 LISDSVER 8 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 0 LIS(0.199)DS(0.801)VER;LIS(0.008)DS(0.992)VER ; 109.29 0.011503 28635000 4922.9 4171 4658.3 5108.2 4962.2 4694.4 3190.2 5434.33 4887.4 4364.4 TRUE FALSE FALSE 4533.24727 4531.522654 4830.940696 5087.063622 4903.029006 3720.728523 3279.708426 7091.2322 4351.264448 4516.062575 1.003805239 1.003423354 1.069724038 1.126437807 1.085686685 0.823887725 0.726231838 1.570224522 0.963508449 1 12.14084976 -4.243815954 24.92166815 0.994730473 1.570225015 0.700772411 0.115621445 1629.618431 2304442.713 0.016015698 0.676223929 5.70E-05 4.243815954 0.575494542 LISDS(ph)VERDR ddPTM_HeLa_Curcumin_4h_R1 1 LISDSVERDR 10 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 0 LIS(0.013)DS(0.987)VERDR 68.463 0.020164 9841800 2607 2766.3 2363.2 2518.9 2777.7 2907.8 2358.4 1297.3 2946.5 2578.3 TRUE FALSE FALSE 2400.653199 3005.406646 2450.782271 2508.477459 2744.577742 2304.689502 2424.570357 1692.840798 2623.276322 2667.895733 0.899830218 1.126508285 0.91861996 0.940245688 1.028742506 0.86386041 0.90879502 0.634522848 0.983275429 1 11.38148657 -3.753763466 1.201459243 0.964244256 5.26E-13 0.684901993 0.068606516 2.013732451 1.037400346 0.01018996 3.261801428 0.000176294 3.753763466 -0.964244256 LISS(ph)VEDFTEFV ddPTM_HeLa_Curcumin_4h_R1 1 LISSVEDFTEFV 12 0 H3BMQ0;A0A2R8YDR3;A0A2R8Y7X5;P49815-3;P49815-5;A0A2R8Y6C9;A0A2R8Y5F1;P49815;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDZ2;A0A2R8YGU4;X5D2U8;P49815-2;P49815-6;P49815-7;P49815-4 H3BMQ0 TSC2 Tuberin 1 0 LIS(0.017)S(0.983)VEDFTEFV 108.47 0.00508 0 318.02 364.42 354.77 399.3 295.18 240.32 163.83 60.499 248.66 276.09 TRUE FALSE FALSE 292.8483814 395.918841 367.9180883 397.6478024 291.6601713 190.474923 168.4266289 78.9448666 221.3826201 285.6841069 1.02507761 1.385862326 1.287849339 1.39191433 1.020918435 0.666732655 0.589555473 0.276336221 0.774921022 1 8.158276969 -4.987297335 1.795736881 1.093130963 0.378982545 0.69495067 0.191848607 0.172005218 1.036731325 0.028389931 0.128128125 1.03E-05 4.987297335 -0.714148418 LISWYDNEFGYSNR ddPTM_HeLa_Curcumin_4h_R1 4 LISWYDNEFGYSNR 14 0 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 ;;; ;;; 268.14 2.97E-49 1959499000 5191.77 4408.18 4918.31 4206.97 4102.28 9187.93 6521.5 6211.38 4873.05 4813.62 FALSE FALSE TRUE 4780.835926 4789.203437 5100.586895 4189.562673 4053.36299 7282.249749 6704.475738 8105.201168 4338.488607 4980.892937 0.959835111 0.961515033 1.024030623 0.841126827 0.813782396 1.462036996 1.346038918 1.627258661 0.871026272 1 12.28218869 -5.250611663 24.90833723 0.962020561 1.465204325 0.874934454 0.095202197 170.8173315 392951.2156 0.012563293 0.031681065 5.62E-06 5.250611663 0.503183765 LITDLQDQNQK ddPTM_HeLa_Curcumin_4h_R1 1 LITDLQDQNQK 11 0 P33176 P33176 KIF5B Kinesin-1 heavy chain 0 0 123.86 0.0015985 1434300 474.51 264.16 363.72 751.15 493.42 563.67 445.59 218.24 526.92 566.54 FALSE FALSE TRUE 436.9520328 286.9928133 377.1997832 748.0419403 487.5362888 446.7584881 458.0920562 284.7803713 469.1181943 586.2272228 0.745362917 0.489559001 0.643436143 1.2760273 0.831650715 0.762090996 0.781424059 0.485784966 0.800232702 1 9.195316154 -9.113693664 0.996659723 0.993186216 0.763424731 0.038218265 0.21677493 0.805268801 1.501370773 0.12192063 0.040182842 7.70E-10 9.113693664 -0.229761485 LITEDVQGK ddPTM_HeLa_Curcumin_4h_R1 1 LITEDVQGK 9 0 P61247;D6RAT0;D6RG13;D6RB09;E9PFI5;H0Y8L7;D6RAS7;D6RGE0;D6RED7 P61247 RPS3A 40S ribosomal protein S3a 0 0 147.51 7.05E-06 8702100 3301.8 2642.2 3641.3 3468.8 3235.9 3744.8 2686.7 2724.8 3743.5 2926.7 FALSE FALSE TRUE 3040.459046 2870.579995 3776.249781 3454.447025 3197.314006 2968.086267 2762.081571 3555.578977 3332.847416 3028.402607 1.003981122 0.947885855 1.246944436 1.140682886 1.055775741 0.980083117 0.912058907 1.174077373 1.100529833 1 11.5643413 LITLEEEMTK ddPTM_HeLa_Curcumin_4h_R1 1 LITLEEEMTK 10 0 P07237;H7BZ94;I3L398;H0Y3Z3 P07237 P4HB Protein disulfide-isomerase 0 0 109.66 0.0085906 1785600 436.01 196.43 436.74 291.65 536.56 418.74 333.51 338.24 367.08 234.4 FALSE FALSE TRUE 401.4993484 213.4085339 452.9259686 290.4432296 530.1618724 331.8886038 342.867393 441.3678189 326.8122424 242.5453826 1.655357625 0.879870528 1.867386482 1.197479938 2.18582546 1.368356719 1.413621605 1.819732927 1.347427186 1 7.922110904 -11.21890438 0.307919331 2.53E-13 1.604944961 0.129040409 0.361305258 11.88843585 0.552816683 7.917450371 0.14137235 6.04E-12 11.21890438 1.604944961 LITPAVVSER ddPTM_HeLa_Curcumin_4h_R1 2 LITPAVVSER 10 0 P62851 P62851 RPS25 40S ribosomal protein S25 0 0 ; ; 109.48 0.005517 13252300 6285.2 4844.5 4778.7 6422.8 5682.2 3375.8 3280.8 3569.5 6043.3 5674.9 FALSE FALSE TRUE 5787.719788 5263.236993 4955.802826 6396.224155 5614.443476 2675.621027 3372.850418 4657.824118 5380.36511 5872.102353 0.985629923 0.896312203 0.84395716 1.089256244 0.956121528 0.45564959 0.574385495 0.793212352 0.916258741 1 12.5196614 -5.306968063 9.691453117 0.979514038 0.604574517 0.711949622 0.100502778 0.183958349 38.48255767 0.013633744 0.030587281 4.93E-06 5.306968063 -0.374939521 LITPPPPPPS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 LITPPPPPPSPER 13 0 J3QKY4;J3QR53;Q96HE9 J3QKY4 PRR11 Proline-rich protein 11 1 0 LIT(0.118)PPPPPPS(0.882)PER 103.13 0.0055187 6682100 2200.7 1575.5 1762.4 1717.3 1812.6 1423.1 831.97 727.15 2083.4 1529 TRUE FALSE FALSE 2026.512273 1711.6792 1827.716094 1710.194268 1790.985929 1127.933018 855.3128391 948.8546876 1854.856232 1582.132636 1.28087382 1.081880975 1.155223053 1.080942412 1.132007449 0.71291938 0.540607544 0.599731442 1.172377201 1 10.62765484 -5.16668895 3.064659877 1.13076516 0.575179701 0.916880375 0.071271698 0.073053901 1.314990822 0.015078099 0.043334384 6.81E-06 5.16668895 -0.555585459 LIVAYVDDLDRR ddPTM_HeLa_Curcumin_4h_R1 2 LIVAYVDDLDRR 12 1 O14776;O14776-2 O14776 TCERG1 Transcription elongation regulator 1 0 0 ; ; 259.35 3.55E-66 11910000 5025.4 3959.8 4833.8 4298.4 4166.1 5993.5 4650.3 4512.8 4906.5 4638.3 FALSE FALSE TRUE 4627.634287 4302.067467 5012.94488 4280.61436 4116.421978 4750.380539 4780.774902 5888.731946 4368.269225 4799.48058 0.964194814 0.896361053 1.044476542 0.891891172 0.857680724 0.989769718 0.996102562 1.226951927 0.910154579 1 12.22866256 -4.231302386 2.887061581 0.966095344 1.283660732 0.670935199 0.057563393 0.222082208 2.425472362 0.007865803 0.169471881 5.87E-05 4.231302386 0.317565388 LIYSGK(ac)QMNDEK ddPTM_HeLa_Curcumin_4h_R1 2 LIYSGKQMNDEK 12 1 S4R3E9;Q15843 S4R3E9 NEDD8-MDP1;NEDD8 NEDD8 0 1 ; LIYSGK(1)QMNDEK;LIYSGK(1)QMNDEK 294.01 1.06E-113 7802600 4720.3 3481.8 3310.1 2876.5 3545.6 3205.1 3009.8 1907 3181.2 3127.5 FALSE TRUE FALSE 4346.683274 3782.751277 3432.775218 2864.597805 3503.321036 2540.326131 3094.246888 2488.435521 2832.230319 3236.180392 1.343152342 1.168893825 1.060749032 0.885178654 1.082548131 0.784976677 0.956141659 0.768942154 0.875176899 1 11.66007631 -6.442418166 2.472969195 1.166996918 0.900227145 0.259958721 0.145620667 0.219956894 2.646866167 0.023739022 0.037572801 3.61E-07 6.442418166 -0.266769773 LKAEAELLQQQK ddPTM_HeLa_Curcumin_4h_R1 1 LKAEAELLQQQK 12 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 103.88 0.0026053 2712200 4205.8 3095.7 3581.8 3599.1 4146.3 3666 3118.9 2860.8 3744.7 4222.6 FALSE FALSE TRUE 3872.906492 3363.278514 3714.544659 3584.207878 4096.858081 2905.630276 3206.40794 3733.04475 3333.915779 4369.335036 0.886383502 0.76974608 0.850139582 0.820309692 0.937638805 0.665005144 0.73384346 0.854373656 0.763025896 1 12.09319802 -8.198444512 0.289710511 1.049261488 0.759341517 0 0.102570452 1.167245212 0.25235836 0.131047119 0.062798097 6.33E-09 8.198444512 -0.28991997 LKATVT(ph)PS(ph)PVKGK ddPTM_HeLa_Curcumin_4h_R1 1 LKATVTPSPVKGK 13 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 2 0 LKAT(0.109)VT(0.895)PS(0.996)PVKGK 120.92 0.0089273 117410000 4920.2 3351.6 3750.3 4207.8 3195.3 4827 4220.9 1694.8 4532 3632.3 TRUE FALSE FALSE 4530.760978 3641.29737 3889.289417 4190.389239 3157.198134 3825.825788 4339.327094 2211.536718 4034.850939 3758.522155 1.205463422 0.968810937 1.034792202 1.114903429 0.840010516 1.017906941 1.154530136 0.588405928 1.073520595 1 11.87594979 -4.255047169 24.85918766 1.067793803 0.588405696 0.650671829 0.099289921 349.9837362 1361039.996 0.015701383 0.198313686 5.56E-05 4.255047169 -0.479388107 LKATVTPS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 1 LKATVTPSPVK 11 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 LKATVT(0.003)PS(0.997)PVK 84.62 0.010101 715320000 13600 8992.5 11171 10079 11952 13753 11085 9644.8 10195 9703.4 TRUE FALSE FALSE 12523.54565 9769.77163 11585.00709 10037.29577 11809.48021 10900.47277 11396.01527 12585.45512 9076.634007 10040.59243 1.247291506 0.973027409 1.153817085 0.999671667 1.176173646 1.085640399 1.134994309 1.253457424 0.90399387 1 13.29355678 -9.681415687 1.552431183 1.000108107 1.140408106 0.327053063 0.093338754 0.452427251 1.966527832 0.064418325 0.014389988 2.08E-10 9.681415687 0.140299999 LKATVTPSPVK(ac)GK ddPTM_HeLa_Curcumin_4h_R1 2 LKATVTPSPVKGK 13 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 0 1 ; LKATVTPSPVK(1)GK;LKATVTPSPVK(1)GK 98.582 0.0020979 7929100 8530.5 5453.5 6543.5 6189 6757.5 8940.8 7521.4 10369 8614.2 6768.6 FALSE TRUE FALSE 7855.301924 5924.87624 6786.007866 6163.391558 6676.921226 7086.377296 7732.430241 13530.46037 7669.243812 7003.808346 1.121575796 0.845950652 0.968902564 0.880005742 0.953327232 1.01178915 1.104032243 1.931871876 1.095010519 1 12.77392389 -4.257267867 3.683681079 1.015273431 2.035668602 0.917615803 0.084229942 0.063891226 1.587990201 0.013500706 0.178710457 5.53E-05 4.257267867 1.020395171 LKDDEVAQLK ddPTM_HeLa_Curcumin_4h_R1 2 LKDDEVAQLK 10 1 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 0 ; ; 111.86 0.0022985 16630400 12969.1 11324.6 11942.7 13524.7 14843.9 14499.7 11208.9 11224.9 13157.4 12487.7 FALSE FALSE TRUE 11942.58205 12303.44796 12385.30697 13468.73837 14666.89619 11492.29877 11523.39157 14647.32034 11714.06614 12921.64665 0.924230663 0.952157902 0.958492931 1.042339165 1.13506402 0.889383458 0.891789714 1.133549054 0.906545927 1 13.65750231 -6.286256414 23.133217 0.961824138 1.010700747 0.142962356 0.081515348 635.6552804 592524.8916 0.012524008 0.019138443 5.17E-07 6.286256414 0.048876609 LKDDEVAQLK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 LKDDEVAQLKK 11 2 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 1 ; LKDDEVAQLK(1)K;LKDDEVAQLK(1)K 162.68 1.41E-08 73182000 9193.9 11766.9 8426.6 7892.8 16950.9 21160.6 15487.3 14773.5 21747 8435.7 FALSE TRUE FALSE 8466.193114 12783.9784 8738.897209 7860.141685 16748.77159 16771.65303 15921.83196 19277.87214 19361.40851 8728.839947 0.969910454 1.464567856 1.001152188 0.900479529 1.918785508 1.921406869 1.824049021 2.208526248 2.218096405 1 13.09157422 -5.755497046 24.76109362 1.021306379 1.954554469 0.333779593 0.416028788 31.37617753 130739.7306 0.025108165 0.04917007 1.76E-06 5.755497046 0.93324809 LKDDEVAQLKK ddPTM_HeLa_Curcumin_4h_R1 1 LKDDEVAQLKK 11 2 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 0 79.201 0.010292 28726000 13579 10034 10935 12038 10491 12659 10247 9361 12698 10752 FALSE FALSE TRUE 12504.20782 10901.29425 11340.26072 11988.18995 10365.90168 10033.3807 10534.50324 12215.12581 11305.06117 11125.6312 1.123909969 0.979836025 1.019291447 1.077528972 0.93171358 0.90182575 0.946867917 1.097926543 1.016127622 1 13.44159957 -5.76345948 24.99921425 1.05123909 0.963121071 0.18841635 0.062553787 55.24682839 683706.2471 0.010265354 0.0192935 1.72E-06 5.76345948 -0.088118019 LKDISTLEPLK ddPTM_HeLa_Curcumin_4h_R1 1 LKDISTLEPLK 11 1 Q92688-2;Q92688 Q92688-2 ANP32B Acidic leucine-rich nuclear phosphoprotein 32 family member B 0 0 96.604 0.00077045 0 2426 1922.8 2094 2536.6 2384.3 2279.5 1750.5 2358.4 2844.5 2274.4 FALSE FALSE TRUE 2233.97954 2088.998264 2171.605482 2526.104221 2355.86878 1806.706005 1799.614319 3077.465303 2532.465467 2353.435231 0.949241989 0.887637882 0.92273858 1.073368916 1.001034041 0.767688858 0.764675524 1.307648183 1.076071877 1 11.20055243 -8.981581467 0.964665664 0.997844541 0.948813083 0.023920999 0.149862176 2.418132776 4.319222025 0.073241286 0.027152912 1.04E-09 8.981581467 -0.049031458 LKDLFDYS(ph)PPLHK ddPTM_HeLa_Curcumin_4h_R1 2 LKDLFDYSPPLHK 13 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 LKDLFDY(0.003)S(0.997)PPLHK;LKDLFDYS(1)PPLHK ; 140.77 0.0091658 200922000 4377.6 3573.8 3733.5 4002.4 3753 5444.9 4470.1 4216.7 4708.9 4516.4 TRUE FALSE FALSE 4031.108341 3882.703347 3871.866794 3985.839129 3708.247926 4315.566363 4595.518975 5502.352419 4192.345451 4673.344564 0.862574605 0.830818977 0.828500176 0.852887921 0.79348909 0.923442794 0.983346918 1.177390698 0.897076043 1 12.1902397 -4.293763426 2.116324885 0.902141792 1.240790204 0.69056195 0.060189921 0.395606639 2.054224976 0.011577408 0.247244834 5.08E-05 4.293763426 0.338648412 LKDLGHPVEEEDELES(ph)GDQEDEDDESEDPGKDLDHI ddPTM_HeLa_Curcumin_4h_R1 2 LKDLGHPVEEEDELESGDQEDEDDESEDPGKDLDHI 36 2 O60763;O60763-2 O60763 USO1 General vesicular transport factor p115 1 0 LKDLGHPVEEEDELES(0.969)GDQEDEDDES(0.031)EDPGKDLDHI;LKDLGHPVEEEDELES(0.989)GDQEDEDDES(0.011)EDPGKDLDHI ; 80.74 1.65E-08 127636400 5974.6 4019.45 4253.22 5457.4 5043.3 5179.3 3067.77 2857.8 5382.2 4791.5 TRUE FALSE FALSE 5501.704106 4366.873348 4410.848075 5434.818725 4983.161941 4105.054797 3153.84337 3729.130064 4791.786126 4958.004268 1.109661026 0.880772406 0.889641847 1.096170643 1.005074153 0.82796516 0.636111467 0.752143375 0.966474788 1 12.2755438 -5.109161523 2.761103828 1.028741651 0.695556923 0.677128237 0.080833848 0.109120972 1.596980835 0.012586995 0.039018718 7.78E-06 5.109161523 -0.333184728 LKDVLLQVDDERR ddPTM_HeLa_Curcumin_4h_R1 3 LKDVLLQVDDERR 13 2 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ;; ;; 75.739 0.010583 166839000 13225.9 9579 10761.2 11045.5 10344 13227.9 10962.3 10147.2 12124.7 10947.2 FALSE FALSE TRUE 12179.05606 10406.96608 11160.01954 10999.79665 10220.65456 10484.28443 11269.87263 13241.03457 10794.65074 11327.61439 1.075165136 0.918725313 0.985204754 0.971060302 0.902277762 0.925550965 0.994902567 1.16891643 0.952950054 1 13.46755644 -7.272226087 24.77570199 1.035494646 0.976111946 0 0.07653967 1026.790409 2358403.218 0.012669784 0.014564594 5.34E-08 7.272226087 -0.0593827 LKDYAFIHFDER ddPTM_HeLa_Curcumin_4h_R1 1 LKDYAFIHFDER 12 1 O60506-4;O60506-3;O60506-2;O60506;B7Z645;O60506-5 O60506-4 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 0 115.12 0.001877 30857000 15185 11871 13257 11398 11745 28378 19250 18166 15883 13527 FALSE FALSE TRUE 13983.09123 12897.07634 13748.31608 11350.8381 11604.94855 22492.08291 19790.10319 23704.72977 14140.67464 13997.06224 0.999001861 0.921413088 0.982228688 0.810944318 0.829098874 1.606914546 1.413875487 1.693550358 1.010260181 1 13.77283644 -5.256227925 24.99870172 0.967839892 1.555689705 0.901487882 0.095798473 100.0685808 480014.5619 0.013707434 0.03382293 5.54E-06 5.256227925 0.587849813 LKDYAFVHFEDR ddPTM_HeLa_Curcumin_4h_R1 2 LKDYAFVHFEDR 12 1 O43390;B4DT28;O43390-4;O43390-3;O43390-2 O43390 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 0 ; ; 90.861 0.0066553 72740000 29660 19579.1 25888 22732 23599 48606 38178 31342 31399 28090 FALSE FALSE TRUE 27312.3797 21271.43016 26847.43205 22637.94101 23317.59734 38524.5677 39249.17193 40898.03152 27954.60826 29066.12541 0.939663588 0.731828885 0.923667385 0.778842749 0.802225856 1.325411184 1.350340693 1.40706857 0.961759019 1 14.82705115 -5.211074341 7.196912127 0.924275514 1.362922829 0.850470724 0.091534604 0.090895712 11.14999006 0.015068911 0.038541106 6.15E-06 5.211074341 0.438647315 LKEDILENEDEQNS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 3 LKEDILENEDEQNSPPK 17 1 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 LKEDILENEDEQNS(1)PPK;LKEDILENEDEQNS(1)PPK;LKEDILENEDEQNS(1)PPK ;; 96.163 0.0012704 172718000 17023.1 15912.7 17853.6 18422 18689.2 19228.1 16911.4 11780 18150.5 18692.1 TRUE FALSE FALSE 15675.70367 17288.12288 18515.27012 18345.77465 18466.3435 15239.97531 17385.88837 15371.66777 16159.43556 19341.64908 0.810463658 0.893828794 0.957274638 0.9485114 0.954745038 0.787935674 0.898883456 0.794744425 0.835473516 1 14.23942318 -9.556931325 1.330717224 0.999949185 0.876405241 0 0.079171461 0.416492753 1.322444083 0.046055222 0.010887884 2.77E-10 9.556931325 -0.123543943 LKEDILENEDEQNS(ph)PPKK ddPTM_HeLa_Curcumin_4h_R1 2 LKEDILENEDEQNSPPKK 18 2 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 LKEDILENEDEQNS(1)PPKK;LKEDILENEDEQNS(1)PPKK ; 82.56 0.0039724 174434000 5706.3 4718 4992.3 6026.4 5456.2 5043.4 4574.1 3686 5386.1 4900 TRUE FALSE FALSE 5254.640334 5125.802897 5177.31903 6001.464354 5391.138379 3997.341989 4702.436935 4809.844432 4795.258305 5070.274635 1.036362073 1.010951727 1.021112149 1.183656663 1.063283306 0.788387667 0.927452115 0.948635878 0.945759086 1 12.30784818 -5.281511998 24.9655237 1.032831722 0.892087899 0.491345435 0.069401458 486.9831093 605689.5411 0.00948728 0.021240016 5.23E-06 5.281511998 -0.140743823 LKEDILENEDEQNS(ph)PPKKGK ddPTM_HeLa_Curcumin_4h_R1 1 LKEDILENEDEQNSPPKKGK 20 3 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 LKEDILENEDEQNS(1)PPKKGK 55.031 0.0116 24717000 1054.7 648.27 796.07 1089.2 884.03 1269.4 728.24 606.74 1332.3 1321.5 TRUE FALSE FALSE 971.2193821 704.3035702 825.5730545 1084.693179 873.4885196 1006.112131 748.6724544 791.7322329 1186.150023 1367.422027 0.710255768 0.515059401 0.603744154 0.79323951 0.638784883 0.735772945 0.547506505 0.578996255 0.867435218 1 10.41724285 -8.722249088 0.636000249 1.008092961 0.633389312 0.617650541 0.090290152 0.318454245 0.246629088 0.060627054 0.020780332 1.90E-09 8.722249088 -0.374703649 LKEFLEDYDDDRDDPK ddPTM_HeLa_Curcumin_4h_R1 1 LKEFLEDYDDDRDDPK 16 2 P49756 P49756 RBM25 RNA-binding protein 25 0 0 63.16 0.013794 40319000 5222.6 4100.1 4297 4726 4910.6 5332.4 5347.7 3597.7 4533.8 4308.9 FALSE FALSE TRUE 4809.225699 4454.494374 4456.2506 4706.445064 4852.044302 4226.400131 5497.742069 4694.622168 4036.453483 4458.633954 1.078632099 0.999071559 0.999465452 1.055580053 1.088235624 0.947913683 1.233055264 1.052928367 0.9053117 1 12.12238605 -4.763117363 24.99939696 1.032652317 1.142991797 0.332549847 0.069745032 30.73282693 457909.8692 0.007572938 0.024603981 1.73E-05 4.763117363 0.11033948 LKEFLEDYDDDRDDPKYYR ddPTM_HeLa_Curcumin_4h_R1 1 LKEFLEDYDDDRDDPKYYR 19 3 P49756 P49756 RBM25 RNA-binding protein 25 0 0 45.14 0.015037 43259000 5408.9 3711.1 4030.9 4579.4 3048.7 5147.8 3743.6 3955.5 6235.3 4753.8 FALSE FALSE TRUE 4980.779858 4031.870948 4180.2887 4560.451656 3012.346244 4080.088252 3848.635341 5161.513741 5551.30319 4918.994196 1.012560629 0.819653528 0.849825906 0.927110599 0.612390689 0.829455797 0.782402903 1.049302669 1.128544367 1 12.26414764 -7.262422808 24.94410165 1.005931411 0.83121585 0.411646189 0.110734369 62.78532864 1592509.093 0.016623782 0.019595243 5.46E-08 7.262422808 -0.174715562 LKEGCS(ph)PFLDQEVMGVVSKPTAAK ddPTM_HeLa_Curcumin_4h_R1 1 LKEGCSPFLDQEVMGVVSKPTAAK 24 2 E7EVA0 E7EVA0 MAP4 Microtubule-associated protein 1 0 LKEGCS(1)PFLDQEVMGVVSKPTAAK 49.559 0.0076134 20443000 1738.2 1578.8 1263.4 1562.7 1665.7 2613.7 2378.7 1812.2 1517.5 1215.8 TRUE FALSE FALSE 1600.619636 1715.264437 1310.222715 1556.233961 1645.837615 2071.589158 2445.43992 2364.731438 1351.034047 1258.04896 1.272303136 1.363432181 1.04147196 1.237021779 1.308246077 1.646668154 1.943835255 1.879681565 1.073912137 1 10.29697235 -5.178394205 1.550980779 1.148238499 1.941331541 0.890804586 0.105987977 0.11335844 0.503014475 0.019763087 0.079359587 6.63E-06 5.178394205 0.793093042 LKFS(ph)DDEEEEEVVK ddPTM_HeLa_Curcumin_4h_R1 2 LKFSDDEEEEEVVK 14 1 Q5JSZ5;Q5JSZ5-5 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 LKFS(1)DDEEEEEVVK;LKFS(1)DDEEEEEVVK ; 149.09 0.0022685 33303000 9114.8 6927 8817.5 7955.5 9104.6 8330.9 7173.3 4324.4 7047.8 6577 TRUE FALSE FALSE 8393.353962 7525.739014 9144.284307 7922.582249 8996.033591 6602.977431 7374.563492 5642.889653 6274.673973 6805.55026 1.233310113 1.105823736 1.343650984 1.16413544 1.321867189 0.970234173 1.083610173 0.829159941 0.921993628 1 12.7324961 -4.013288363 1.259613526 1.142500464 0.542665591 0.326088885 0.133027031 2.186251551 1.949848371 0.019296599 1.962351301 9.70E-05 4.013288363 -0.599834873 LKGIS(ph)ICFS(ph)MLK ddPTM_HeLa_Curcumin_4h_R1 1 LKGISICFSMLK 12 1 E5RIW1;E7ESC6;Q9UIA9 E5RIW1 XPO7 Exportin-7 2 0 LKGIS(1)ICFS(1)MLK 60.631 0.0095232 0 5883.1 4720.3 4571.1 4549.1 4670.6 6205.1 4742.3 4821.5 5771.8 4661.7 TRUE FALSE FALSE 5417.446427 5128.301699 4740.508987 4530.27703 4614.906145 4918.092314 4875.356175 6291.553155 5138.64798 4823.693728 1.123090879 1.063148282 0.98275497 0.939171781 0.956716244 1.019569772 1.010710142 1.304301954 1.06529317 1 12.23592259 -4.258278203 24.72307034 1.034886839 1.304302071 0.706966537 0.054340752 144.1834684 1127571.04 0.009686331 0.091346262 5.52E-05 4.258278203 0.269415232 LKGQEDSLASAVDAATEQKTCDS(ph)D ddPTM_HeLa_Curcumin_4h_R1 2 LKGQEDSLASAVDAATEQKTCDSD 24 2 J3KR35;Q8WUD4 J3KR35 CCDC12 Coiled-coil domain-containing protein 12 1 0 LKGQEDSLASAVDAAT(0.02)EQKT(0.103)CDS(0.877)D;LKGQEDSLASAVDAAT(0.001)EQKT(0.01)CDS(0.989)D ; 106.18 2.78E-06 87548000 15753.8 10446.9 10079.9 12288.9 6100.5 15180.2 8268.5 9341.3 21830.7 17492.2 TRUE FALSE FALSE 14506.87011 11349.88349 10453.46996 12238.05179 6027.755522 12031.6554 8500.491856 12189.41937 19435.92683 18100.05265 0.801482205 0.627063562 0.577538097 0.676133491 0.333024198 0.664730409 0.469639068 0.673446625 1.073804989 1 14.14370627 -7.584934101 0.673721504 0.97026633 0.539649276 0.742958575 0.107494104 0.208505082 0.209182854 0.030431803 0.028719352 2.60E-08 7.584934101 -0.430617053 LKISEEDLTPRMRQR ddPTM_HeLa_Curcumin_4h_R1 1 LKISEEDLTPRMRQR 15 3 E9PGM7;O94988-6;O94988-5;O94988-1;O94988;O94988-3 E9PGM7 FAM13A Protein FAM13A 0 0 57.434 0.019884 6495600 2777.4 1754.7 1845.8 2283.3 1575.4 2757.4 1825.2 1853.5 3172.3 2782.7 FALSE FALSE TRUE 2557.565859 1906.368449 1914.206972 2273.85231 1556.614384 2185.484158 1876.4102 2418.623618 2824.306627 2879.398618 0.888229175 0.662071739 0.664794016 0.789696951 0.540603991 0.759007157 0.651667396 0.839975265 0.980866841 1 11.49155181 -7.458598665 2.27133156 0.957787516 0.696649114 0.670978728 0.082227395 0.120190842 1.204294374 0.01483485 0.016385321 3.48E-08 7.458598665 -0.261138403 LKLS(ph)PSPS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 LKLSPSPSSR 10 1 P20700;Q03252 P20700;Q03252 LMNB1;LMNB2 Lamin-B1;Lamin-B2 2 0 LKLS(0.855)PS(0.167)PS(0.969)S(0.01)R 129.76 0.011793 270600000 16073 12968 13959 14387 14108 16209 10494 5706.4 14871 12103 TRUE FALSE FALSE 14800.80509 14088.89614 14476.33282 14327.47041 13939.77131 12847.07069 10788.4334 7446.255091 13239.68851 12523.57835 1.181835149 1.124989659 1.155926239 1.144039667 1.113082134 1.025830663 0.861449747 0.594578872 1.057180954 1 13.61235922 -4.394333171 1.491993873 1.102350563 0.471944502 0.913350336 0.049896957 0.260420295 0.635200611 0.010714672 0.223582496 4.03E-05 4.394333171 -0.630406062 LKLSILYPATTGR ddPTM_HeLa_Curcumin_4h_R1 1 LKLSILYPATTGR 13 1 P30041 P30041 PRDX6 Peroxiredoxin-6 0 0 127.3 3.21E-07 0 7518.6 5255.4 5812.5 4789.3 3690.6 11721 7547.3 8107.7 7659.4 7746.2 FALSE FALSE TRUE 6923.494876 5709.653358 6027.916363 4769.483146 3646.592005 9289.932477 7759.056925 10579.70041 6819.182983 8015.379873 0.863776263 0.712337213 0.752043753 0.595041435 0.454949368 1.159013375 0.96802111 1.319925016 0.850762296 1 12.96855518 -4.35501974 1.516462152 0.855453042 1.415861953 0.39917912 0.189781021 0.925427298 2.224355673 0.031003703 0.730728364 4.42E-05 4.35501974 0.560408911 LKNDSDLFGLGLEEAGPKES(ph)S(ph)EEGKEGK ddPTM_HeLa_Curcumin_4h_R1 1 LKNDSDLFGLGLEEAGPKESSEEGKEGK 28 3 Q3YEC7-2;Q3YEC7 Q3YEC7-2 RABL6 Rab-like protein 6 2 0 LKNDSDLFGLGLEEAGPKES(1)S(1)EEGKEGK 48.374 0.010646 71429000 1633.2 1154.3 1439.8 1670.8 1691.5 1279.9 1473.4 716.59 1598.4 1442.5 TRUE FALSE FALSE 1503.930497 1254.072549 1493.160255 1663.886672 1671.329967 1014.434313 1514.739639 935.0749922 1423.059519 1492.626768 1.007573045 0.840178252 1.000357415 1.114737259 1.119723968 0.679630256 1.014814736 0.626462698 0.953392737 1 10.54363775 -3.644761651 0.888488361 0.999269434 6.87E-13 0.385205014 0.12552668 4.177518435 1.13916761 0.018158505 5.277672761 0.000226589 3.644761651 -0.999269434 LKPGGVGAPSSS(ph)SPSPSPSAR ddPTM_HeLa_Curcumin_4h_R1 1 LKPGGVGAPSSSSPSPSPSAR 21 1 Q92797 Q92797 SYMPK Symplekin 1 0 LKPGGVGAPS(0.048)S(0.166)S(0.592)S(0.117)PS(0.051)PS(0.02)PS(0.006)AR 73.688 0.0010366 128600000 1194.3 990.21 1057.5 1070.2 1263.1 1174.7 1119.9 803.98 1067.1 954.44 TRUE FALSE FALSE 1099.769895 1075.79934 1096.69188 1065.771796 1248.038357 931.0539784 1151.32138 1049.109801 950.0417998 987.606719 1.113570689 1.089299333 1.110454049 1.079145955 1.263699744 0.94273759 1.165769084 1.062274872 0.961963686 1 9.947792841 -9.24502944 0.739425332 0.991796339 1.105651702 0.276116909 0.077381454 0.959925903 0.837639693 0.0673729 0.014165749 5.69E-10 9.24502944 0.113855362 LKPGGVGAPSSSSPS(ph)PSPSAR ddPTM_HeLa_Curcumin_4h_R1 2 LKPGGVGAPSSSSPSPSPSAR 21 1 Q92797 Q92797 SYMPK Symplekin 1 0 LKPGGVGAPSS(0.002)S(0.128)S(0.273)PS(0.582)PS(0.009)PS(0.005)AR;LKPGGVGAPSSS(0.001)S(0.007)PS(0.382)PS(0.382)PS(0.226)AR ; 157.62 3.31E-07 17249000 4364.2 4071.7 4669.3 4472.5 4613.5 4394.8 4960 2546.2 3458.9 3318.3 TRUE FALSE FALSE 4018.768965 4423.639605 4842.348366 4453.99398 4558.487026 3483.26894 5099.164251 3322.524659 3079.467324 3433.610678 1.170420686 1.288334648 1.410278806 1.297175014 1.327607424 1.014462403 1.485073507 0.967647462 0.896859782 1 11.74551075 -8.19115602 0.915607565 1.026788207 1.261599339 0.340202426 0.157961515 0.425812268 0.757000422 0.045235003 0.030905719 6.44E-09 8.19115602 0.234811132 LKPSGLPGS(ph)S(ph)SPTRSLMT(ph)GSRS(ph)TK ddPTM_HeLa_Curcumin_4h_R1 1 LKPSGLPGSSSPTRSLMTGSRSTK 24 3 Q8WXI7 Q8WXI7 MUC16 Mucin-16 4 0 LKPS(0.009)GLPGS(0.805)S(0.805)S(0.274)PT(0.073)RS(0.076)LMT(0.487)GS(0.487)RS(0.536)T(0.448)K 54.672 0.0047915 0 1638.2 1508.1 1115.2 1241.2 1418.9 1898.3 1306.6 1246.2 1106.5 1041.6 TRUE FALSE FALSE 1508.534741 1638.453444 1156.530293 1236.064243 1401.980544 1504.571182 1343.259679 1626.160643 985.1197183 1077.795522 1.399648366 1.520189507 1.073051677 1.146844849 1.300785274 1.395970897 1.246302895 1.508784003 0.914013556 1 10.07386778 -9.34408995 1.038937601 0.997775308 1.320333707 0.514053965 0.140045979 0.413041509 0.789615715 0.098451103 0.025110362 4.53E-10 9.34408995 0.322558399 ASQLVGIEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 ASQLVGIEKK 10 1 Q9NPD8 Q9NPD8 UBE2T Ubiquitin-conjugating enzyme E2 T 0 1 ; ASQLVGIEK(1)K;ASQLVGIEK(1)K 125.22 0.00072554 11426700 8639.6 7861.9 8110.2 7456.9 7321.1 13976.8 14482.3 26299 9760.3 8895.1 FALSE TRUE FALSE 7955.766544 8541.447604 8410.771146 7426.045324 7233.800664 11077.85413 14888.63436 34317.44403 8689.619509 9204.204063 0.864362251 0.927994159 0.913796683 0.806810157 0.785923543 1.203564594 1.617590642 3.728453194 0.944092444 1 13.16807725 -4.081418124 1.553123835 0.916299681 5.848851926 0.988733576 0.09009537 0.129526925 0.204621119 0.014256022 1.103781793 8.29E-05 4.081418124 4.932552245 up LKQAIEEEGGDPDNIELTVSTDT(ph)PNKKPTK ddPTM_HeLa_Curcumin_4h_R1 1 LKQAIEEEGGDPDNIELTVSTDTPNKKPTK 30 3 Q9NWH9;H0YL55;H7BXE3;H0YMW8;H0YNF3;H0YMR6;H0YLE6;H0YKU6 Q9NWH9 SLTM SAFB-like transcription modulator 1 0 LKQAIEEEGGDPDNIELT(0.044)VS(0.142)T(0.142)DT(0.645)PNKKPT(0.027)K 81.763 1.60E-06 19677000 4680.8 3151.4 3897 4204 3382.9 6828.7 5317.7 2015.3 5404.3 3523.9 TRUE FALSE FALSE 4310.309741 3423.792974 4041.426248 4186.604962 3342.561127 5412.350645 5466.90035 2629.755693 4811.461811 3646.355263 1.182087161 0.938963081 1.108346817 1.148161564 0.916685536 1.484317971 1.499278034 0.721201173 1.319526339 1 11.83223941 -5.274252954 24.99355761 1.073259838 1.261366977 0.073999962 0.229202538 1080.679542 2107922.312 0.029114275 0.065499347 5.32E-06 5.274252954 0.188107139 LKQIEEQTK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 LKQIEEQTKK 10 2 P26038 P26038 MSN Moesin 0 1 ; LKQIEEQTK(1)K;LKQIEEQTK(1)K 114.71 1.35E-05 0 2504.24 2559.02 2069.23 2144.87 3970 6129.7 4011.2 4492.2 6299.1 2207.17 FALSE TRUE FALSE 2306.026762 2780.210286 2145.917484 2135.995096 3922.660343 4858.331124 4123.743476 5861.8511 5608.10449 2283.868993 1.009701856 1.217324765 0.939597451 0.935252899 1.717550505 2.127237218 1.805595456 2.566631938 2.4555281 1 11.15726418 -5.584591936 2.854766359 1.01137717 2.126119757 0.342163149 0.495231747 0.058246865 0.959207199 0.025810056 0.057673715 2.60E-06 5.584591936 1.114742587 LKQLMEQDASS(ph)SPSAQVIGLK ddPTM_HeLa_Curcumin_4h_R1 1 LKQLMEQDASSSPSAQVIGLK 21 1 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 0 LKQLMEQDAS(0.001)S(0.527)S(0.393)PS(0.078)AQVIGLK 89.668 0.00022893 11139000 4860.1 3514.3 3980.8 5663.6 3298.4 5028.7 2856.5 2287.9 5863.6 5156 TRUE FALSE FALSE 4475.417957 3818.060433 4128.33195 5640.165524 3259.068734 3985.690935 2936.645702 2985.470178 5220.37775 5335.170616 0.83885189 0.7156398 0.773795675 1.057166852 0.61086495 0.747059695 0.550431451 0.559582887 0.97848375 1 12.38131869 -3.389998139 0.174916427 1.025278882 5.35E-18 0.579331414 0.112924862 13.67856142 0.31150089 0.193474512 3.23363013 0.000407382 3.389998139 -1.025278882 LKQVEDEK(ac)NSFR ddPTM_HeLa_Curcumin_4h_R1 1 LKQVEDEKNSFR 12 2 P35579 P35579 MYH9 Myosin-9 0 1 LKQVEDEK(1)NSFR 84.507 0.007835 2478800 1037.8 878.31 1088.7 761.65 1307.3 956.45 1024.2 949.1 1696.3 1015.1 FALSE TRUE FALSE 955.6570349 954.2272027 1129.04818 758.4984941 1291.711301 758.0714886 1052.936296 1238.476221 1510.220134 1050.374649 0.909824923 0.908463664 1.074900447 0.722121859 1.229762449 0.721715332 1.002438793 1.179080456 1.437791872 1 10.03668829 -4.311990808 4.327136918 0.949102178 1.186823421 0.014560745 0.210545488 0.209634498 7.744875493 0.017036095 0.13146118 4.88E-05 4.311990808 0.237721243 KPVTVSPTTPT(ph)S(ph)PTEGEAS ddPTM_HeLa_Curcumin_4h_R1 1 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 2 0 KPVTVSPT(0.014)T(0.415)PT(0.597)S(0.819)PT(0.112)EGEAS(0.042) 79.471 0.0072971 42815000 1246.4 1263.4 1159.4 1150.3 1537.9 2694.8 3970.4 24484 0 2028.9 TRUE FALSE FALSE 1147.746125 1372.602666 1202.368384 1145.540363 1519.561547 2135.868103 4081.798738 31949.05889 0 2099.404124 0.5467009 0.653805835 0.572718883 0.54565024 0.723806117 1.017368728 1.944265371 15.21815573 0 1 11.03576419 -4.256744843 3.886406795 0.761453346 16.67867862 0.995469927 0.293301754 0.009722418 0.289770784 0.035113208 0.44052239 5.54E-05 4.256744843 15.91722527 up LKS(ph)IS(ph)REPS(ph)PALGPNLDGSGLLPR ddPTM_HeLa_Curcumin_4h_R1 1 LKSISREPSPALGPNLDGSGLLPR 24 2 Q9BRZ2 Q9BRZ2 TRIM56 E3 ubiquitin-protein ligase TRIM56 3 0 LKS(1)IS(1)REPS(1)PALGPNLDGSGLLPR 59.539 0.0051338 24763000 1501.7 1936.4 1582 1624 1584.4 2006.9 1749.6 1155 1686 1505.1 TRUE FALSE FALSE 1382.83886 2103.773788 1640.630312 1617.280318 1565.507065 1590.646318 1798.689067 1507.154183 1501.050018 1557.402113 0.887913821 1.350822482 1.053440404 1.038447492 1.005204148 1.021345935 1.15492913 0.967736059 0.963816606 1 10.60492577 LKS(ph)PSMAVPSPGWVASPK ddPTM_HeLa_Curcumin_4h_R1 2 LKSPSMAVPSPGWVASPK 18 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 0 LKS(0.857)PS(0.126)MAVPS(0.017)PGWVASPK;LKS(0.733)PS(0.169)MAVPS(0.098)PGWVASPK ; 75.548 0.0041399 52255000 4469.5 3773.3 3971.8 4161.1 4140 5653.2 3563.7 2545.4 4667.7 3731.1 TRUE FALSE FALSE 4115.734359 4099.447239 4118.998402 4143.882471 4090.633204 4480.662595 3663.687831 3321.480742 4155.664988 3860.755447 1.066043787 1.061825152 1.066889229 1.073334617 1.05954217 1.160566282 0.948956203 0.860318864 1.076386486 1 11.91466746 -4.530183792 24.13903996 1.048730602 0.882478146 0.712066215 0.042024956 44.2488858 146218.7762 0.006513934 0.024491888 2.95E-05 4.530183792 -0.166252456 LKS(ph)PSQDNTDSYFR ddPTM_HeLa_Curcumin_4h_R1 1 LKSPSQDNTDSYFR 14 1 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 0 LKS(0.993)PS(0.007)QDNTDSYFR 67.118 0.016324 8632500 1641.9 1339.3 1402.8 1720.1 1446.6 1849.2 1823.2 1298.3 1440.6 1178.7 TRUE FALSE FALSE 1511.941882 1455.063124 1454.789002 1712.982682 1429.35024 1465.655075 1874.354085 1694.145693 1282.569784 1219.659737 1.239642366 1.193007426 1.192782673 1.404475879 1.171925412 1.201691776 1.536784423 1.389031417 1.051579998 1 10.252263 -9.213231696 0.046501214 6.82E-13 2.195568975 0.625460971 0.094997255 69.6888743 0.851534106 24.15228224 16.35134475 6.12E-10 9.213231696 2.195568975 ADIDVSGPKVDIDT(ph)PDIDIHGPEGK ddPTM_HeLa_Curcumin_4h_R1 2 ADIDVSGPKVDIDTPDIDIHGPEGK 25 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 ADIDVS(0.038)GPKVDIDT(0.962)PDIDIHGPEGK;ADIDVS(0.001)GPKVDIDT(0.999)PDIDIHGPEGK ; 104.23 1.34E-07 278430000 10818.3 6996.5 9747.5 9960.2 7777.4 10904.6 11717.7 20316.4 10587.7 8185.4 TRUE FALSE FALSE 9962.02014 7601.246284 10108.75092 9918.987332 7684.659585 8642.86304 12046.46713 26510.77683 9426.255799 8469.842041 1.176175434 0.897448411 1.193499345 1.171094725 0.907296682 1.02042789 1.422277661 3.130020218 1.112919905 1 13.04811935 -4.256504046 2.831675924 1.070762877 3.51706954 0.973254038 0.102478866 0.049094071 0.535659274 0.015142183 0.277419922 5.54E-05 4.256504046 2.446306664 up LKSPS(ph)QKQDGGTAPVASASPK ddPTM_HeLa_Curcumin_4h_R1 2 LKSPSQKQDGGTAPVASASPK 21 2 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 0 LKS(0.404)PS(0.567)QKQDGGT(0.029)APVASASPK;LKS(0.131)PS(0.821)QKQDGGT(0.035)APVAS(0.011)ASPK ; 69.256 0.0024432 69431000 6174.4 4657.1 4759.3 5079.2 4300.8 6080.9 3761.7 2563.29 6177.3 5283.1 TRUE FALSE FALSE 5685.689725 5059.638972 4935.683845 5058.183616 4249.515769 4819.652794 3867.243178 3344.825321 5499.665645 5466.687332 1.040061262 0.925540216 0.902865583 0.925273993 0.777347507 0.881640471 0.707419858 0.611855978 1.006032595 1 12.41645115 -3.442740137 0.338840703 1.027609084 1.53E-16 0.871475539 0.047116555 2.559210268 0.136018948 0.016543555 1.205406796 0.000360794 3.442740137 -1.027609084 LKSPVLSNTTTEPAS(ph)TMSPPPAKK ddPTM_HeLa_Curcumin_4h_R1 1 LKSPVLSNTTTEPASTMSPPPAKK 24 2 Q9P275;A0A075B784 Q9P275 USP36 Ubiquitin carboxyl-terminal hydrolase 36;Ubiquitin carboxyl-terminal hydrolase 1 0 LKSPVLSNTTTEPAS(0.389)T(0.306)MS(0.306)PPPAKK 83.606 5.39E-05 29891000 2225.3 1579.8 1617.4 1624.8 1549.3 2099.4 1422.1 891.99 2167 1789.8 TRUE FALSE FALSE 2049.165157 1716.350873 1677.342267 1618.077008 1530.825609 1663.960775 1462.000299 1163.953645 1929.285522 1851.995417 1.106463406 0.926757624 0.90569461 0.873693851 0.826581748 0.898469165 0.789418961 0.628486245 1.041733421 1 10.85486481 -4.866224207 0.402153373 1.052731332 0.532981506 0.782670059 0.059972627 1.353097645 0.206929387 0.02194395 0.311298615 1.36E-05 4.866224207 -0.519749826 FYQGLPWGVSS(ph)LPR ddPTM_HeLa_Curcumin_4h_R1 2 FYQGLPWGVSSLPR 14 0 Q5JTC6 Q5JTC6 AMER1 APC membrane recruitment protein 1 1 0 FYQGLPWGVS(0.03)S(0.97)LPR;FYQGLPWGVS(0.21)S(0.79)LPR ; 175.6 0.00018864 15637300 7021.9 5893.8 6082.5 6061.8 5838.3 9445.4 4737 1447.62 7162.2 6479.1 TRUE FALSE FALSE 6466.109206 6403.23381 6307.922801 6036.717878 5768.682086 7486.317568 4869.907471 1888.992674 6376.524579 6704.248243 0.964479383 0.955100942 0.940884432 0.900431735 0.860451743 1.116652799 0.726391281 0.28176055 0.951117015 1 12.71085985 -4.373833448 2.848798464 0.970109835 0.236243244 0.902207174 0.068024444 0.064220359 0.80370397 0.009026557 0.094347605 4.23E-05 4.373833448 -0.733866591 down LKTEEGEIDYS(ph)AEEGENRR ddPTM_HeLa_Curcumin_4h_R1 2 LKTEEGEIDYSAEEGENRR 19 2 B7WPG3;V9GYK2;Q8WVV9-2;Q8WVV9-5;Q8WVV9;C9IYN3;Q8WVV9-3;Q8WVV9-4 B7WPG3 HNRNPLL Heterogeneous nuclear ribonucleoprotein L-like 1 0 LKTEEGEIDY(0.458)S(0.541)AEEGENRR;LKTEEGEIDY(0.017)S(0.983)AEEGENRR ; 64.295 0.011392 31776000 4370.9 3729.2 3862.3 4646.1 3877.1 4410.1 3351.1 2814.4 4607.1 4247.2 TRUE FALSE FALSE 4024.938653 4051.535431 4005.440236 4626.875669 3830.868115 3495.395548 3445.122847 3672.497604 4101.712656 4394.789884 0.915843251 0.921895139 0.911406539 1.052809302 0.87168402 0.795349867 0.783910707 0.835648052 0.933312573 1 12.10157848 -1.183703042 0.211091302 0.988323709 1.24E-09 0.473981765 0.058313101 28.22526915 0.355559521 0.05054763 9.311377134 0.065508395 1.183703042 -0.988323707 LKTEKEPDATPPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 LKTEKEPDATPPSPR 15 2 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 0 LKTEKEPDATPPS(1)PR 86.179 0.0077936 44319000 1606.4 1598.5 1353.6 1861.1 1847.8 2359.1 1569.2 1375.4 2285 2179.9 TRUE FALSE FALSE 1479.251745 1736.667217 1403.765607 1853.399261 1825.766192 1869.796067 1613.227529 1794.753128 2034.341217 2255.651363 0.655798041 0.76991828 0.622332702 0.821669205 0.809418611 0.828938416 0.715193649 0.795669561 0.901886369 1 11.13932838 -9.431696796 1.140384455 1.001149858 0.745322856 0.535124743 0.072035995 0.245754403 0.567536467 0.050008678 0.012313284 3.70E-10 9.431696796 -0.255827002 LKVPEWVDTVK ddPTM_HeLa_Curcumin_4h_R1 1 LKVPEWVDTVK 11 1 P39019;M0R2L9;M0QYF7;M0R140 P39019 RPS19 40S ribosomal protein S19 0 0 113.24 0.0016924 1696500 1907.5 1402.4 1791.2 1534.8 1551.1 2955.9 2100.5 1863 1510.8 1050.1 FALSE FALSE TRUE 1756.519362 1523.617207 1857.583448 1528.449404 1532.604146 2342.81302 2159.434377 2431.020124 1345.06902 1086.590897 1.616541577 1.402199495 1.709551822 1.406646613 1.410470261 2.156113241 1.987348121 2.237291082 1.23787989 1 10.08559315 -1 0.091123277 0.570907768 4.954295333 0.72343426 0.202219364 58.9821601 0.388860011 2.47252024 32.46977422 0.1 1 4.383387565 up LLAAVEAFYS(ph)PPSHDRPR ddPTM_HeLa_Curcumin_4h_R1 1 LLAAVEAFYSPPSHDRPR 18 1 J3QK89;Q8IWX8 J3QK89 CHERP Calcium homeostasis endoplasmic reticulum protein 1 0 LLAAVEAFY(0.065)S(0.917)PPS(0.018)HDRPR 62.966 0.0088536 5462600 1643.7 1716.6 1589.2 1886 1557.3 2612.1 1858.1 1474.3 1984.5 1578.1 TRUE FALSE FALSE 1513.599411 1864.975255 1648.09715 1878.196232 1538.730215 2070.321016 1910.233285 1923.807283 1766.805315 1632.938858 0.926917382 1.142097419 1.009282829 1.15019385 0.942307305 1.267849685 1.169813111 1.17812573 1.081978855 1 10.67325506 -5.758245248 0.554075438 0.968266909 1.221332257 0.26295553 0.092102912 0.737230914 0.363982898 0.019270222 0.09082155 1.74E-06 5.758245248 0.253065348 LLACIASRPGQCGR ddPTM_HeLa_Curcumin_4h_R1 1 LLACIASRPGQCGR 14 1 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 0 84.821 0.01205 10131000 2682.4 1830 2086.2 2440 1977.3 2502.6 1691.3 2162.1 2810.3 2566.7 FALSE FALSE TRUE 2470.08521 1988.177046 2163.516407 2429.903927 1953.721989 1983.53255 1738.753326 2821.314337 2502.017121 2655.892634 0.930039557 0.748590896 0.81460989 0.914910451 0.735617835 0.746842144 0.654677566 1.062284785 0.9420626 1 11.37498111 -7.442775772 3.535280855 0.971178623 0.804014288 0.28121568 0.107182158 0.194140435 4.454149854 0.018069299 0.020187406 3.61E-08 7.442775772 -0.167164334 LLADPTGAFGK ddPTM_HeLa_Curcumin_4h_R1 1 LLADPTGAFGK 11 0 P30044-4;P30044-2;P30044-3;P30044 P30044-4 PRDX5 "Peroxiredoxin-5, mitochondrial" 0 0 145.46 1.69E-05 2684500 5477.5 4667.5 4770.2 4912.1 5322.7 7568.3 5261 5091.8 5325.8 4449.9 FALSE FALSE TRUE 5043.950095 5070.937902 4946.987808 4891.775032 5259.230279 5998.549268 5408.609501 6644.26638 4741.573064 4604.533694 1.095431249 1.101292387 1.074373245 1.062382286 1.142185209 1.302748479 1.174626979 1.442983551 1.029761835 1 12.16883935 -1 0.319422914 1.031144244 4.625595688 0.819075961 0.05463607 15.17731908 0.19352643 0.01856782 32.29301813 0.1 1 3.594451444 LLAEPVPGIK ddPTM_HeLa_Curcumin_4h_R1 2 LLAEPVPGIK 10 0 P61088;Q5JXB2;F8VZ29;F8VSD4;F8VV71 P61088 UBE2N;UBE2NL Ubiquitin-conjugating enzyme E2 N;Putative ubiquitin-conjugating enzyme E2 N-like 0 0 ; ; 172.21 1.27E-12 6591500 12154.3 9871.2 10467.6 10355.5 10608.4 13116 10130.4 10759 11769 10707.5 FALSE FALSE TRUE 11192.27433 10724.42254 10855.53846 10312.65168 10481.90176 10395.59375 10414.63176 14039.36957 10477.97014 11079.58483 1.010170914 0.967944441 0.979778451 0.930779614 0.946055463 0.93826564 0.939983936 1.267138597 0.945700611 1 13.4356162 -4.255957959 24.99376044 0.984238711 1.267138717 0.877462204 0.033285626 177.9302183 811288.1219 0.005362419 0.062415044 5.55E-05 4.255957959 0.282900006 LLAS(ph)PSSR ddPTM_HeLa_Curcumin_4h_R1 2 LLASPSSR 8 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 0 LLAS(0.945)PS(0.055)SR;LLAS(0.914)PS(0.079)S(0.008)R ; 106.68 0.012264 150682000 11853.9 9222.5 9133.2 10263.5 10284.2 14767.6 11267.7 5229.2 11221.6 7655.4 TRUE FALSE FALSE 10915.65131 10019.65181 9471.684426 10221.03236 10161.56763 11704.63329 11583.84134 6823.559008 9990.618555 7921.42458 1.37799094 1.264880036 1.195704678 1.2903023 1.282795478 1.477591963 1.462343196 0.861405539 1.26121488 1 12.95154419 -9.395021328 1.025918502 0.993393495 1.294297867 0.010405953 0.181450144 0.528844615 0.960277729 0.119694941 0.027991271 4.03E-10 9.395021328 0.300904372 LLAS(ph)SPALPSSGAQAR ddPTM_HeLa_Curcumin_4h_R1 2 LLASSPALPSSGAQAR 16 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 0 LLAS(0.5)S(0.5)PALPSSGAQAR;LLAS(0.924)S(0.076)PALPSSGAQAR ; 236.05 1.36E-22 51203000 4788.8 3477.8 4453.1 4428.7 4617.7 7157.6 6178.6 3100.1 4301 3284.4 TRUE FALSE FALSE 4409.761427 3778.405535 4618.135803 4410.375213 4562.636943 5673.033077 6351.954887 4045.306219 3829.191061 3398.532656 1.297548641 1.111775557 1.358861683 1.297729244 1.342531441 1.669259546 1.869028646 1.190309651 1.126718925 1 11.73069627 -6.313258253 0.183947643 0.897330406 1.835099142 0.423797879 0.18991573 3.672307168 0.334473504 0.495190047 1.067649167 4.86E-07 6.313258253 0.937768736 LLASQGSQGAPLLS(ph)TPKR ddPTM_HeLa_Curcumin_4h_R1 1 LLASQGSQGAPLLSTPKR 18 1 H3BRB3;Q14807-2;Q14807 H3BRB3 KIF22 Kinesin-like protein;Kinesin-like protein KIF22 1 0 LLASQGSQGAPLLS(0.5)T(0.5)PKR 132.48 0.00011663 29201000 1322.6 1186.3 1005.1 1111.5 1160.8 1829.5 1795.5 445.89 1536.2 893.11 TRUE FALSE FALSE 1217.914814 1288.838486 1042.34989 1106.900908 1146.958218 1450.041077 1845.876898 581.8398084 1367.682703 924.145506 1.317882094 1.394627229 1.127906681 1.19775609 1.241101332 1.569061439 1.997387733 0.629597617 1.479943033 1 9.851976211 -10.97735711 0.247061326 0.488669755 1.386757253 0 0.361468085 20.96745824 0.82247663 6.033274745 0.228717432 1.05E-11 10.97735711 0.898087498 LLASQGSQGAPLLST(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 LLASQGSQGAPLLSTPK 17 0 H3BRB3;Q14807-2;Q14807 H3BRB3 KIF22 Kinesin-like protein;Kinesin-like protein KIF22 1 0 LLASQGSQGAPLLS(0.13)T(0.87)PK 119.96 0.0018727 21700000 3223.7 2756 2975 2832 3058.9 4614.4 3667.5 1793.6 3369.1 2798.3 TRUE FALSE FALSE 2968.540743 2994.21636 3085.256117 2820.281934 3022.424615 3657.321425 3770.400179 2340.460383 2999.518159 2895.540717 1.02521119 1.034078486 1.065519852 0.974008729 1.04382045 1.263087548 1.302140273 0.808298212 1.035909508 1 11.49961707 -5.499058764 23.27613261 1.015840996 1.144135581 0.11064248 0.125376955 389.0841958 380199.0854 0.016343023 0.036301176 3.17E-06 5.499058764 0.128294585 LLASS(ph)PALPSSGAQAR ddPTM_HeLa_Curcumin_4h_R1 2 LLASSPALPSSGAQAR 16 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 0 LLAS(0.008)S(0.99)PALPS(0.001)SGAQAR;LLAS(0.084)S(0.916)PALPSSGAQAR ; 198.48 8.99E-08 66020000 3375.6 2884 2968.6 3295.5 2945.1 5150.1 4473.6 2210.01 3640.4 2279.4 TRUE FALSE FALSE 3108.417698 3133.280109 3078.618927 3281.864094 2909.981606 4081.911206 4599.117176 2883.831875 3241.057228 2358.60898 1.317902935 1.328444068 1.305268891 1.391440515 1.233770256 1.73064346 1.949927781 1.222683327 1.374139272 1 11.20372055 -6.987691421 0.077989554 0.279327959 2.399215538 0.169648412 0.23236887 11.42728245 0.660410688 8.130149071 9.296849295 1.03E-07 6.987691421 2.119887579 LLDDISNGYDDSEDGGHTLGDPSYSYETTEK ddPTM_HeLa_Curcumin_4h_R1 1 LLDDISNGYDDSEDGGHTLGDPSYSYETTEK 31 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 0 126.88 1.04E-12 4049100 621.14 446.37 369.83 517.98 635.31 751.29 523.16 631.91 691 510.72 FALSE FALSE TRUE 571.9761136 484.9522338 383.5362251 515.836736 627.7343432 595.4639852 537.8384616 824.57645 615.1990288 528.467482 1.082329818 0.917657662 0.725751798 0.976099294 1.187839109 1.126775072 1.017732367 1.560316345 1.164118985 1 9.045670891 -1.942038618 1.246796897 1.0140968 199.9999998 0.599605064 0.130348701 292.5221738 1.582817943 0.019158244 165232.1688 0.011427767 1.942038618 198.985903 LLDEEEATDNDLR ddPTM_HeLa_Curcumin_4h_R1 2 LLDEEEATDNDLR 13 0 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 0 ; ; 345.85 3.67E-140 96088000 3681.4 2713 2955.6 3331.7 3048.4 3920.8 2778.6 2729.8 3902 2849.5 FALSE FALSE TRUE 3390.013305 2947.499631 3065.137136 3317.914308 3012.049821 3107.581883 2856.560038 3562.103454 3473.960362 2948.519913 1.149733902 0.999653968 1.039551106 1.125281296 1.021546372 1.053946378 0.968811513 1.208098829 1.178204816 1 11.52577522 LLDESESAAS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 2 LLDESESAASSR 12 0 Q8N108-17;Q8N108;Q8N108-13;Q8N108-12;Q8N108-19;Q8N108-16;Q8N108-14;Q8N108-18;Q8N108-15 Q8N108-17 MIER1 Mesoderm induction early response protein 1 1 0 LLDESES(0.008)AAS(0.973)S(0.019)R;LLDES(0.009)ES(0.228)AAS(0.76)S(0.003)R ; 133.98 0.0019594 12538700 1638.53 1669.31 1928.82 1953.01 2150.93 2027.1 1823.55 1589.31 1697.16 1734.57 TRUE FALSE FALSE 1508.838622 1813.597718 2000.303766 1944.928962 2125.281565 1606.65661 1874.713905 2073.883303 1510.985794 1794.846178 0.840650658 1.010447436 1.114470861 1.083618744 1.184102343 0.89515003 1.044498369 1.15546576 0.841846957 1 10.80964449 -7.01774287 6.882381432 0.92464491 1.073768059 0.474112065 0.085420008 0.134288452 29.4603988 0.015122379 0.019055163 9.60E-08 7.01774287 0.149123149 LLDLPAAAS(ph)SEDIER ddPTM_HeLa_Curcumin_4h_R1 1 LLDLPAAASSEDIER 15 0 P22466 P22466 GAL Galanin peptides;Galanin;Galanin message-associated peptide 1 0 LLDLPAAAS(0.946)S(0.054)EDIER 174.4 0.00011038 5956600 3892 3356.1 4384.3 3405 3741.6 4834.3 3095.6 1975.9 3517 3353.2 TRUE FALSE FALSE 3583.944093 3646.18633 4546.786015 3390.911012 3696.983864 3831.611686 3182.454205 2578.342814 3131.193899 3469.72345 1.032919235 1.050857909 1.310417409 0.977285672 1.065498135 1.10429887 0.917206875 0.743097498 0.902433276 1 11.76060496 -4.435477641 2.952355442 1.044846969 0.738322632 0.478209787 0.101387834 0.187503675 2.725156563 0.012942633 0.108818877 3.67E-05 4.435477641 -0.306524336 LLDLPAAAS(ph)SEDIERS ddPTM_HeLa_Curcumin_4h_R1 5 LLDLPAAASSEDIERS 16 1 P22466 P22466 GAL Galanin peptides;Galanin;Galanin message-associated peptide 1 0 LLDLPAAAS(0.928)S(0.072)EDIERS;LLDLPAAAS(0.957)S(0.043)EDIERS;LLDLPAAAS(0.936)S(0.064)EDIERS;LLDLPAAAS(0.865)S(0.135)EDIERS(0.001);LLDLPAAAS(0.981)S(0.019)EDIERS ;;;; 175.26 6.31E-05 107623000 16165 13230.38 13623.99 12634.93 12896.1 19066.7 12097.9 6775.03 15542.3 14057.49 TRUE FALSE FALSE 14885.52319 14373.95509 14128.90705 12582.65001 12742.32243 15112.05149 12437.33451 8840.705459 13837.34857 14545.98673 1.023342278 0.988173258 0.971326821 0.865025539 0.876002616 1.038915529 0.855035464 0.607776263 0.951282909 1 13.82833354 -3.832799538 1.160960882 0.991713322 3.92E-19 0.744124983 0.061139772 1.34085712 0.752087884 0.009716488 2.05002399 0.00014696 3.832799538 -0.991713322 LLDLSDSTSVAS(ph)FPSADETDGNLPESR ddPTM_HeLa_Curcumin_4h_R1 3 LLDLSDSTSVASFPSADETDGNLPESR 27 0 Q13464 Q13464 ROCK1 Rho-associated protein kinase 1 1 0 LLDLSDS(0.003)T(0.009)S(0.065)VAS(0.839)FPS(0.078)ADET(0.006)DGNLPESR;LLDLSDS(0.001)T(0.004)S(0.015)VAS(0.98)FPS(0.001)ADETDGNLPESR;LLDLSDST(0.001)SVAS(0.998)FPSADETDGNLPESR ;; 133.72 1.56E-08 10010000 3956.68 2837.99 3494.28 3754.8 3673.43 4962.28 3394.78 2469.33 3991.44 3221.86 TRUE FALSE FALSE 3643.504603 3083.29321 3623.781091 3739.263632 3629.626746 3933.047192 3490.02839 3222.21735 3553.589018 3333.819395 1.092892017 0.924853102 1.086975826 1.121615537 1.088729267 1.179742129 1.046855866 0.966524268 1.065921274 1 11.70296024 LLDPEDIS(ph)VDHPDEK ddPTM_HeLa_Curcumin_4h_R1 1 LLDPEDISVDHPDEK 15 0 A0A087WUZ3;Q01082;Q01082-2;F8W6C1;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 LLDPEDIS(1)VDHPDEK 79.332 0.0077354 3275600 2229.2 2004.1 2140.2 1950.8 2085.5 2670.5 2158.4 1158.3 2457.6 2573.6 TRUE FALSE FALSE 2052.756468 2177.325474 2219.517695 1942.728106 2060.631775 2116.608197 2218.958895 1511.460338 2188.007429 2663.032408 0.770834204 0.817611332 0.833455007 0.72951726 0.773791475 0.79481128 0.833245171 0.567571139 0.821622531 1 11.37885427 -13.52287875 0.189324992 2.051197894 0.718698598 0.236698717 0.088765387 24.01087796 0.283400391 9.288959884 0.078252009 3.00E-14 13.52287875 -1.332499296 LLDPEDISVDHPDEK ddPTM_HeLa_Curcumin_4h_R1 2 LLDPEDISVDHPDEK 15 0 A0A087WUZ3;Q01082;Q01082-2;F8W6C1;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 ; ; 113.65 0.0014721 15809000 8559.4 7342.2 7431.5 6848.6 9125.6 10775 8853.7 8389.9 8966.1 8270.1 FALSE FALSE TRUE 7881.914458 7976.827052 7706.917927 6820.262308 9016.78318 8540.143541 9102.110993 10947.94189 7982.541262 8557.485359 0.921054974 0.932146152 0.900605447 0.796993745 1.053672055 0.997973491 1.063643186 1.279341001 0.932813896 1 13.0629712 -3.873222232 1.039700036 0.947467126 1.726142744 0.73916765 0.062534315 1.532298627 0.753716177 0.010189136 1.601353142 0.000133899 3.873222232 0.778675619 LLDPEDVDVPQPDEK ddPTM_HeLa_Curcumin_4h_R1 1 LLDPEDVDVPQPDEK 15 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 246.63 1.45E-28 31674000 11349 9338.1 9978.6 9850.9 9191.8 11098 9134.7 8258.7 11642 10448 FALSE FALSE TRUE 10450.71467 10145.24375 10348.41569 9810.139586 9082.193788 8796.1497 9390.995097 10776.73961 10364.90173 10811.06722 0.96666818 0.93841279 0.957205749 0.90741639 0.840083 0.81362455 0.868646444 0.996824771 0.95873067 1 13.40022133 -6.561381506 1.11054805 0.985040555 0.875608579 0.393819805 0.047978609 0.294905833 0.72721094 0.008831471 0.015099727 2.75E-07 6.561381506 -0.109431976 LLDPEDVDVS(ph)SPDEK ddPTM_HeLa_Curcumin_4h_R1 1 LLDPEDVDVSSPDEK 15 0 F6QMI7;E7ETB9;Q03001;Q5T0V7;F8W9J4;Q03001-14;E9PHM6;A0A494C1D7;Q03001-13 F6QMI7 DST Dystonin 1 0 LLDPEDVDVS(0.905)S(0.095)PDEK 170.26 0.00016937 5925900 5873.2 4553.7 5069.4 5711.2 5319 5751.7 4784.7 7606.5 5996.7 5465.5 TRUE FALSE FALSE 5408.330023 4947.301537 5257.276423 5687.568568 5255.574399 4558.732585 4918.945805 9925.686834 5338.877013 5655.425718 0.956308206 0.874788528 0.929598705 1.005683542 0.929297751 0.806081242 0.869774629 1.755073328 0.944027431 1 12.46541991 -4.257961605 24.99778031 0.95007784 1.75507363 0.939895325 0.062739928 65.1037284 467935.6338 0.009875642 0.096773205 5.52E-05 4.257961605 0.80499579 LLDPEDVDVSS(ph)PDEK ddPTM_HeLa_Curcumin_4h_R1 1 LLDPEDVDVSSPDEK 15 0 F6QMI7;E7ETB9;Q03001;Q5T0V7;F8W9J4;Q03001-14;E9PHM6;A0A494C1D7;Q03001-13 F6QMI7 DST Dystonin 1 0 LLDPEDVDVS(0.027)S(0.973)PDEK 238.88 6.07E-29 10549000 3833.2 3562 3666.5 4205.5 4216.2 4460.3 3939.4 5093.4 4222.7 3652.5 TRUE FALSE FALSE 3529.798175 3869.883408 3802.383715 4188.098755 4165.924569 3535.183502 4049.928962 6646.354213 3759.480375 3779.424103 0.933951332 1.02393468 1.006074897 1.108131462 1.102264381 0.935376239 1.071573036 1.758562689 0.994723077 1 11.8839507 -4.263016385 3.846131166 0.992537501 1.83296754 0.936176015 0.057859306 0.046476207 1.346505391 0.009134192 0.109524462 5.46E-05 4.263016385 0.840430039 LLDQHDQR ddPTM_HeLa_Curcumin_4h_R1 1 LLDQHDQR 8 0 E5RH41;P29084 E5RH41 GTF2E2 Transcription initiation factor IIE subunit beta 0 0 101.43 0.0091376 0 457.76 548.09 551.61 590.52 436.18 598.7 456.48 470.41 684.52 466.97 FALSE FALSE TRUE 421.527813 595.4644574 572.0531518 588.0765847 430.9788384 474.5228713 469.2876002 613.8358435 609.4298686 483.1971727 0.872372267 1.232342594 1.183891761 1.217053033 0.891931623 0.982048112 0.971213465 1.270363069 1.26124469 1 8.916468203 -7.277974932 24.97663294 0.939731348 1.09587189 0 0.159101039 861.3171955 1300999.93 0.022288057 0.025524539 5.27E-08 7.277974932 0.156140541 LLDQIVEK ddPTM_HeLa_Curcumin_4h_R1 1 LLDQIVEK 8 0 Q96AE4;E9PEB5;Q96AE4-2;C9JSZ1 Q96AE4 FUBP1 Far upstream element-binding protein 1 0 0 115.71 0.003328 2701700 3662.9 3235.3 2983.3 3206.9 2915 2730.4 2459.7 2446.3 3349.6 3056.4 FALSE FALSE TRUE 3372.9776 3514.944916 3093.863722 3193.630698 2880.240529 2164.084262 2528.712562 3192.165609 2982.15726 3162.609673 1.066517196 1.11140649 0.978262904 1.00980868 0.910716411 0.684271689 0.799565177 1.009345426 0.942941927 1 11.62689979 -5.654304579 3.249778244 1.033755302 0.824222817 0.479487542 0.086829436 0.132137778 2.761287117 0.01199447 0.025349303 2.22E-06 5.654304579 -0.209532485 RS(ph)S(ph)DGSLSHEEDLAK ddPTM_HeLa_Curcumin_4h_R1 1 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;H0YEF9;E9PJZ7 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 2 0 RS(0.734)S(0.939)DGS(0.309)LS(0.018)HEEDLAK 65.565 0.014859 17207000 3667.8 2822.9 3444.9 3640.6 3862 4361 2631.5 1128.8 4956.8 3452.4 TRUE FALSE FALSE 3377.48976 3066.898897 3572.571024 3625.536162 3815.948172 3456.479441 2705.332808 1472.965924 4413.051441 3572.370643 0.945447742 0.858505235 1.000056092 1.01488242 1.068183723 0.967559021 0.757293427 0.412321696 1.235328549 1 11.80266606 -4.37335086 2.105463467 0.977076304 0.328906938 0.784339088 0.096717472 0.110199657 0.640760251 0.008012834 0.122948169 4.23E-05 4.37335086 -0.648169366 down LLDVVHPAAK ddPTM_HeLa_Curcumin_4h_R1 1 LLDVVHPAAK 10 0 Q99832-3;Q99832;F8WAM2 Q99832-3 CCT7 T-complex protein 1 subunit eta 0 0 91.867 0.0054084 6428400 9768 8158 8683 9716.5 9185 10674 8247.3 8379.8 9773.4 9271.8 FALSE FALSE TRUE 8994.852493 8863.141169 9004.799618 9676.295698 9075.474874 8460.092079 8478.697042 10934.76244 8701.282472 9593.99436 0.937550321 0.923821803 0.938587129 1.008578423 0.945953743 0.881811242 0.883750472 1.139750768 0.906950968 1 13.22791588 -9.359163189 1.100586995 0.999807308 0.951124286 0 0.075856684 1.199896098 2.616563688 0.044330899 0.011713252 4.37E-10 9.359163189 -0.048683022 LLEAAAQS(ph)TK ddPTM_HeLa_Curcumin_4h_R1 1 LLEAAAQSTK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 LLEAAAQS(0.972)T(0.028)K 126.34 0.0034678 3049900 2036.9 1774.3 1872 1813.1 1483 2244.2 1749.2 1697.5 2596.4 2477.3 TRUE FALSE FALSE 1875.677216 1927.662586 1941.377967 1805.597873 1465.316194 1778.727623 1798.277844 2215.059936 2311.581416 2563.385991 0.731718603 0.751998565 0.757349059 0.704380019 0.571633066 0.693897692 0.70152441 0.864114864 0.901768764 1 11.32383502 -9.143679546 0.527867371 1.047627294 0.70604875 0.593130692 0.074156719 0.565609939 0.23358615 0.097322683 0.018030396 7.18E-10 9.143679546 -0.341578544 LLEAAAQSTK ddPTM_HeLa_Curcumin_4h_R1 1 LLEAAAQSTK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 117.52 3.95E-07 0 3033.1 2305.1 2825.6 2977.8 2929.3 3081.1 2723.2 2466.8 3196.1 2859.7 FALSE FALSE TRUE 2793.026934 2504.342573 2930.319222 2965.478653 2894.370011 2442.045129 2799.605663 3218.915964 2845.495826 2959.074362 0.943885348 0.846326339 0.990282387 1.002164288 0.978133584 0.825273322 0.946108587 1.087811785 0.96161687 1 11.53093024 -9.123561051 1.076855793 0.997763993 0.948897613 0.012324527 0.071977399 1.123790034 2.484899537 0.037070138 0.012923001 7.52E-10 9.123561051 -0.048866381 LLEAQIATGGVIDPVHSHR ddPTM_HeLa_Curcumin_4h_R1 2 LLEAQIATGGVIDPVHSHR 19 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4;A0A075B730;P58107 Q15149;Q15149-3;Q15149-4;A0A075B730 PLEC;EPPK1 Plectin;Epiplakin 0 0 ; ; 76.573 0.0017698 13131300 6267.8 5844.9 6545.6 5778.2 5863.9 7239.6 5050.5 4107.4 6373 5197.2 FALSE FALSE TRUE 5771.697016 6350.107112 6788.185694 5754.291339 5793.976822 5738.025353 5192.203437 5359.727352 5673.897844 5377.802313 1.073244549 1.180799654 1.262260176 1.070007971 1.077387469 1.066983317 0.96548797 0.996638969 1.055058835 1 12.39280101 -4.769137457 23.2036014 1.069306675 0.981063463 0.216602609 0.074323648 96.55095498 291036.4337 0.012447951 0.038509319 1.70E-05 4.769137457 -0.088243212 LLEATELK ddPTM_HeLa_Curcumin_4h_R1 2 LLEATELK 8 0 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 ; ; 106.04 0.0087004 2479500 1863.05 1681.04 1773.95 1655.08 1806.68 2334.2 1512.56 1529.03 2024.41 1622.66 FALSE FALSE TRUE 1715.587627 1826.341607 1839.694148 1648.231717 1785.136521 1850.060608 1554.998363 1995.224208 1802.337288 1679.047314 1.021762527 1.087724921 1.095677371 0.981646975 1.063184168 1.101851385 0.926119443 1.188307316 1.073428529 1 10.71342717 -9.476364625 0.009694932 3.90E-05 2.019348483 0 0.071090295 5991.642978 13.31945323 1453.123607 1322.782249 3.34E-10 9.476364625 2.019309501 LLEDGEDFNLGDALDS(ph)SNSMQTIQK ddPTM_HeLa_Curcumin_4h_R1 2 LLEDGEDFNLGDALDSSNSMQTIQK 25 0 P05783 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 LLEDGEDFNLGDALDS(0.333)S(0.333)NS(0.333)MQT(0.001)IQK;LLEDGEDFNLGDALDS(0.333)S(0.333)NS(0.333)MQT(0.002)IQK ; 118.08 1.50E-08 45820400 7237.3 5540.6 6249.5 7050.5 6891.4 10174.7 7333.1 3855.4 6917.9 6967.3 TRUE FALSE FALSE 6664.460068 6019.504776 6481.111968 7021.326899 6809.224556 8064.352527 7538.84705 5030.893712 6159.023678 7209.413156 0.924410895 0.83495073 0.89897913 0.973911017 0.944490822 1.118586541 1.045694967 0.697822916 0.854303054 1 12.81566611 -9.261190095 1.145291283 0.997920719 0.937564412 0 0.116445376 1.367509684 3.366627313 0.060433676 0.01888281 5.48E-10 9.261190095 -0.060356307 LLEDS(ph)EESS(ph)EETVSR ddPTM_HeLa_Curcumin_4h_R1 3 LLEDSEESSEETVSR 15 0 A2AB15;A0A140T947;O60231 A2AB15 DHX16 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 2 0 LLEDS(1)EES(0.125)S(0.754)EET(0.121)VS(0.001)R;LLEDS(0.974)EES(0.382)S(0.568)EET(0.075)VS(0.001)R;LLEDS(1)EES(0.395)S(0.603)EET(0.002)VSR ;; 174.47 0.00026102 346493500 9124.8 7107.2 8340 8536.4 8020.5 9669.9 7802.3 7217.5 8504.1 7750.5 TRUE FALSE FALSE 8402.562452 7721.514699 8649.087737 8501.078639 7924.860776 7664.253738 8021.211539 9418.082525 7571.221506 8019.829298 1.047723354 0.962802874 1.078462822 1.060007429 0.988158286 0.955662952 1.000172353 1.1743495 0.944062676 1 12.96935581 -9.575130459 1.310436037 0.99974286 1.030804561 0.095236331 0.063510853 1.554071785 4.719055552 0.043434763 0.009803283 2.66E-10 9.575130459 0.031061701 LLEEENQES(ph)LR ddPTM_HeLa_Curcumin_4h_R1 1 LLEEENQESLR 11 0 P48681 P48681 NES Nestin 1 0 LLEEENQES(1)LR 89.629 0.017852 4604400 1996.9 1336.4 1603.9 1768.2 1492.3 1691 1784.4 2132.6 1695.2 1421.6 TRUE FALSE FALSE 1838.843258 1451.912461 1663.341945 1760.883657 1474.505297 1340.267539 1834.465462 2782.819923 1509.240801 1471.000494 1.250062978 0.987023775 1.130755531 1.197065306 1.002382598 0.911126505 1.24708691 1.891787211 1.025996121 1 10.52258202 -4.289099651 3.479361296 1.09773906 1.966540074 0.849648188 0.103574773 0.086165634 1.804935519 0.016659115 0.188125592 5.14E-05 4.289099651 0.868801014 LLEELEEGQK ddPTM_HeLa_Curcumin_4h_R1 3 LLEELEEGQK 10 0 E5RIF1;D6RG00;H0YBX6;I3L0A0;Q13404-8;Q15819;Q13404;Q13404-7;Q13404-2;Q13404-1 E5RIF1 UBE2V2;UBE2V1;TMEM189-UBE2V1 Ubiquitin-conjugating enzyme E2 variant 1;Ubiquitin-conjugating enzyme E2 variant 2 0 0 ;; ;; 172.59 0.0037964 7401100 3832.11 3293.73 3522.27 3648.35 3817.3 4655.68 3746.26 3057.9 3448.74 3123.88 FALSE FALSE TRUE 3528.79445 3578.425345 3652.808425 3633.254094 3771.781191 3690.039488 3851.369973 3990.239633 3070.42185 3232.434597 1.091683171 1.1070372 1.130048672 1.12399926 1.166854604 1.141566635 1.191476535 1.234437856 0.949879033 1 11.65840546 -1 0.058780918 0.760554778 1.88391701 0.923810072 0.022236101 40.90951922 0.18176058 0.730389073 3.981837456 0.1 1 1.123362232 SASSSSSSSSS(ph)SDSDVSVK ddPTM_HeLa_Curcumin_4h_R1 1 SASSSSSSSSSSDSDVSVK 19 0 Q7Z4V5-2;Q7Z4V5;Q7Z4V5-4;Q7Z4V5-3;A0A087WT54 Q7Z4V5-2 HDGFRP2 Hepatoma-derived growth factor-related protein 2 1 0 SASSSSSSS(0.05)S(0.083)S(0.613)S(0.254)DSDVSVK 278.27 2.10E-122 0 1741.4 1320.5 1821.6 1786.8 2052.6 1995.6 1132.3 340.68 1937.4 1326.4 TRUE FALSE FALSE 1603.566352 1434.638136 1889.110098 1779.406695 2028.124086 1581.690065 1164.069291 444.5517637 1724.872067 1372.492301 1.168360909 1.045279551 1.376408521 1.296478453 1.477694326 1.152421812 0.848142674 0.323901098 1.256744439 1 10.42258234 -4.373080231 2.379132889 1.147208558 0.232940447 0.760965162 0.152122067 0.194229302 1.551242711 0.02482199 0.32717397 4.24E-05 4.373080231 -0.91426811 down LLEGEEER ddPTM_HeLa_Curcumin_4h_R1 4 LLEGEEER 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8;P20700;E9PBF6;Q03252 P02545;P02545-2;P20700;Q03252 LMNA;LMNB1;LMNB2 Prelamin-A/C;Lamin-A/C;Lamin-B1;Lamin-B2 0 0 ;;; ;;; 187.34 0.00249 444158000 16232.3 13211.3 13626.5 14975.7 14729.2 17625.3 13639.9 13026 17410.7 14722.9 FALSE FALSE TRUE 14947.49633 14353.2259 14131.51008 14913.73452 14553.56391 13969.6141 14022.59888 16997.56744 15500.78977 15234.51968 0.981159672 0.942151522 0.927598006 0.978943533 0.955301789 0.916971089 0.920449032 1.115727164 1.017478076 1 13.89505639 -7.603557647 2.582081549 0.992969559 0.960516271 0.068244721 0.054894204 0.548773907 7.642391669 0.009722356 0.010199814 2.49E-08 7.603557647 -0.032453288 LLELTS(ph)SYSPDVSDYK ddPTM_HeLa_Curcumin_4h_R1 1 LLELTSSYSPDVSDYK 16 0 P38432 P38432 COIL Coilin 1 0 LLELT(0.007)S(0.381)S(0.349)YS(0.261)PDVS(0.002)DYK 101.39 0.0025488 6686700 1837.4 1435.7 1947.4 2066.3 2114.7 2563.5 1991.6 862.99 1598.1 1447.5 TRUE FALSE FALSE 1691.967851 1559.795511 2019.572357 2057.750198 2089.483584 2031.801203 2047.478936 1126.111678 1422.792428 1497.800517 1.129634976 1.041390688 1.348358699 1.373847969 1.395034625 1.356523235 1.366990405 0.751843563 0.949921176 1 10.54862978 -6.768272378 24.93368787 1.061440025 1.285008718 0.270476623 0.184763533 155.7424078 568305.6172 0.028395273 0.037785166 1.71E-07 6.768272378 0.223568693 LLELTSSYS(ph)PDVSDYK ddPTM_HeLa_Curcumin_4h_R1 1 LLELTSSYSPDVSDYK 16 0 P38432 P38432 COIL Coilin 1 0 LLELT(0.161)S(0.032)S(0.376)Y(0.013)S(0.418)PDVSDYK 88.768 0.0066122 9290700 1058.8 813.66 1118.8 973.16 1130.6 1490.2 1071.1 591.81 789.42 862.07 TRUE FALSE FALSE 974.9948628 883.9891448 1160.263712 969.1333218 1117.118333 1181.115722 1101.152183 772.2501446 702.822601 892.0268683 1.093010645 0.990989371 1.300704893 1.086439609 1.252337091 1.324080881 1.234438359 0.865725206 0.787893982 1 9.800943355 -6.778152958 24.99925028 1.041178989 1.18583975 0.272343209 0.149163206 259.3149455 387868.0093 0.019758313 0.026006253 1.67E-07 6.778152958 0.144660761 LLEQWEKDDDIEEGDLPEHK ddPTM_HeLa_Curcumin_4h_R1 2 LLEQWEKDDDIEEGDLPEHK 20 1 Q14696 Q14696 MESDC2 LDLR chaperone MESD 0 0 ; ; 103.85 0.00017228 11270900 6901.1 4856.3 6560.3 5880.3 6816.7 6603.5 4906.1 4035.4 5570.5 5149 FALSE FALSE TRUE 6354.870653 5276.056933 6803.430489 5855.968877 6735.415305 5233.859663 5043.751962 5265.774883 4959.430087 5327.927367 1.192747238 0.990264425 1.276937545 1.099108241 1.264171758 0.98234441 0.946663048 0.988334585 0.930836655 1 12.3793587 -5.036839666 24.84218065 1.110624504 0.966749971 0.246036056 0.108642043 490.0245856 330439.331 0.014530523 0.037059123 9.19E-06 5.036839666 -0.143874533 LLEQYK(ac)EESK ddPTM_HeLa_Curcumin_4h_R1 1 LLEQYKEESK 10 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PQD4 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 1 LLEQYK(1)EESK 143.96 1.61E-05 1803200 469.92 448.88 502.98 485.83 941.67 1049.1 831.36 526.39 1344.5 480.86 FALSE TRUE FALSE 432.7253361 487.679187 521.6208813 483.8197642 930.4412003 831.5048342 854.6857241 686.8838878 1197.011714 497.5698492 0.869677568 0.980122063 1.048336996 0.972365518 1.869971024 1.671131873 1.717720086 1.380477312 2.405715933 1 8.958755256 -5.772835702 24.99605441 0.951773452 1.66476804 0.030550969 0.475325201 46.87806645 102819.8052 0.017779753 0.032432863 1.69E-06 5.772835702 0.712994589 LLEQYK(ac)EESKK ddPTM_HeLa_Curcumin_4h_R1 1 LLEQYKEESKK 11 2 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PQD4 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 1 LLEQYK(0.998)EESK(0.002)K 84.365 0.0077655 6568200 1828.9 1872.5 1527.6 1380.1 2775.1 3817.5 2945.7 2246.2 3564 1749.8 FALSE TRUE FALSE 1684.140635 2034.350556 1584.2142 1374.389512 2742.008745 3025.707468 3028.348414 2931.05604 3173.038117 1810.60542 0.930153316 1.123574764 0.874963801 0.759077321 1.514415408 1.671102624 1.672561222 1.618826503 1.752473555 1 10.82225646 -5.653772938 5.353359873 0.959321769 1.644840734 0.476152145 0.266851096 0.038293908 1.668340026 0.013502261 0.027310598 2.22E-06 5.653772938 0.685518966 RSS(ph)QPS(ph)PTAVPASDSPPTK ddPTM_HeLa_Curcumin_4h_R1 2 RSSQPSPTAVPASDSPPTK 19 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 0 RS(0.125)S(0.853)QPS(0.816)PT(0.206)AVPASDSPPTK;RS(0.098)S(0.898)QPS(0.502)PT(0.502)AVPASDSPPTK ; 138.28 1.98E-06 12474000 2343.3 2288.1 2786.7 2505.6 2640.5 3026.7 2690.4 4035.3 2953.1 2488.4 TRUE FALSE FALSE 2157.825332 2485.873168 2889.977553 2495.232491 2609.013762 2398.928302 2765.885383 5265.644394 2629.152318 2574.871715 0.838032171 0.965435736 1.122377296 0.969070605 1.013259708 0.931669057 1.074183761 2.045012326 1.021080896 1 11.33028484 -4.256457164 3.436672108 0.949940524 2.189493714 0.94762147 0.074165235 0.054610152 1.079184154 0.012274003 0.177271487 5.54E-05 4.256457164 1.23955319 up VSMPDVELNLKS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 VSMPDVELNLKSPK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VSMPDVELNLKS(1)PK;VSMPDVELNLKS(1)PK;VSMPDVELNLKS(1)PK ;; 179.81 0.0012883 1127225000 9482 6420.5 8721.7 9018.8 8402.7 10463 10021.7 29860.4 8126.9 5822.6 TRUE FALSE FALSE 8731.489695 6975.459411 9044.933874 8981.482595 8302.50329 8292.855858 10302.88193 38964.6985 7235.399403 6024.934917 1.449225563 1.157765106 1.501250055 1.490718609 1.378023731 1.37642248 1.710040369 6.467239736 1.200909139 1 12.55672994 -4.25634272 3.84703432 1.278595308 7.005861508 0.989763577 0.156133057 0.023392683 0.672702817 0.029759894 0.378831967 5.54E-05 4.25634272 5.7272662 up LLESSLS(ph)SSEGEEPVEYK ddPTM_HeLa_Curcumin_4h_R1 1 LLESSLSSSEGEEPVEYK 18 0 P08648 P08648 ITGA5 Integrin alpha-5;Integrin alpha-5 heavy chain;Integrin alpha-5 light chain 1 0 LLESSLS(0.921)S(0.078)S(0.001)EGEEPVEYK 254.72 5.58E-42 3713500 2402.2 1844.2 1993.6 3246.3 2003 3610 1525.1 951.74 3544.8 2366.2 TRUE FALSE FALSE 2212.063335 2003.60443 2067.48457 3232.867671 1979.115533 2861.245307 1567.890201 1241.921145 3155.944309 2448.425274 0.903463691 0.8183237 0.844413996 1.320386497 0.808321804 1.168606344 0.640366777 0.507232611 1.288969013 1 11.25763845 -4.606785257 6.117618542 0.962677032 0.539087454 0.466338878 0.184955968 0.101312915 5.694219579 0.019719548 0.076457513 2.47E-05 4.606785257 -0.423589578 LLESSLSS(ph)SEGEEPVEYK ddPTM_HeLa_Curcumin_4h_R1 1 LLESSLSSSEGEEPVEYK 18 0 P08648 P08648 ITGA5 Integrin alpha-5;Integrin alpha-5 heavy chain;Integrin alpha-5 light chain 1 0 LLESSLS(0.02)S(0.98)SEGEEPVEYK 179.81 7.62E-07 7970400 2614 2547.4 2232.1 3168.1 2098.1 3862.6 1795.6 916.79 3687.2 2318.6 TRUE FALSE FALSE 2407.099142 2767.585905 2314.82359 3154.991242 2073.081528 3061.45322 1845.979703 1196.315051 3282.723385 2399.171177 1.00330446 1.153559167 0.964843031 1.315033821 0.864082374 1.276046181 0.769423925 0.498636805 1.368273934 1 11.22832038 -4.530721137 5.306195658 1.037392733 0.553177619 0.54324245 0.172882482 0.067913621 5.976837673 0.017174673 0.077226023 2.95E-05 4.530721137 -0.484215114 LLETTDRPDGHQNNLR ddPTM_HeLa_Curcumin_4h_R1 2 LLETTDRPDGHQNNLR 16 1 Q14974;Q14974-2;J3KTM9 Q14974 KPNB1 Importin subunit beta-1 0 0 ; ; 70.68 0.0059175 6654200 5718.6 4088.7 4530.8 5216.2 5727 5630.2 4533.4 3828.9 4694.5 4919 FALSE FALSE TRUE 5265.966776 4442.109009 4698.715434 5194.616747 5658.709265 4462.433055 4660.595003 4996.313984 4179.525095 5089.934884 1.034584311 0.872724133 0.923138614 1.020566444 1.111744923 0.87671712 0.915649239 0.981606661 0.821135278 1 12.31343148 -5.000682851 0.267749518 1.016880685 0.90474143 0 0.093985258 12.66558917 0.981469238 0.052067031 0.455566834 9.98E-06 5.000682851 -0.112139254 LLFNDVQTLK ddPTM_HeLa_Curcumin_4h_R1 2 LLFNDVQTLK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 171.85 1.36E-12 2070490 1254.4 1011.07 984.8 1173.6 929.43 1349.96 914.706 1074.37 917.51 997.651 FALSE FALSE TRUE 1155.112916 1098.462386 1021.297554 1168.743954 918.3471543 1069.963079 940.3701886 1401.940467 816.8614485 1032.319298 1.118949262 1.064072315 0.989323319 1.132153546 0.889596035 1.03646525 0.910929584 1.358049268 0.791287589 1 10.01167355 LLGELLQDNAK ddPTM_HeLa_Curcumin_4h_R1 1 LLGELLQDNAK 11 0 F2Z393;P37837 F2Z393 TALDO1 Transaldolase 0 0 152.07 7.71E-18 0 442.44 285.73 304.13 386.02 384.01 606.28 178.95 440.26 343.5 320.78 FALSE FALSE TRUE 407.4204071 310.427228 315.4013253 384.4227515 379.4309316 480.5306938 183.9708554 574.4932473 305.8189094 331.9270811 1.22743949 0.93522718 0.950212692 1.158154225 1.14311532 1.447699574 0.554250815 1.730781488 0.921343653 1 8.37472253 -4.216987262 23.28211234 1.088238337 1.730787183 0.440629619 0.227976998 9942.195949 5207007.957 0.02813574 17.86972444 6.07E-05 4.216987262 0.642548846 KYES(ph)DEDSLGSSGR ddPTM_HeLa_Curcumin_4h_R1 4 KYESDEDSLGSSGR 14 1 O00418 O00418 EEF2K Eukaryotic elongation factor 2 kinase 1 0 KYES(0.499)DEDS(0.499)LGS(0.001)SGR;KYES(1)DEDSLGSSGR;KYES(0.906)DEDS(0.09)LGS(0.003)SGR;KY(0.001)ES(0.968)DEDS(0.031)LGSSGR ;;; 241.64 1.89E-28 101762800 9821.73 8018.85 7748.89 7822.09 7663.4 8265.83 5208.15 1759.84 10390.5 7802.6 TRUE FALSE FALSE 9044.329707 8711.963663 8036.07068 7789.724264 7572.01896 6551.403683 5354.276672 2296.407115 9250.688146 8073.739769 1.120215658 1.079049352 0.995334369 0.964822311 0.937857694 0.81144598 0.663171817 0.284429172 1.145774871 1 12.97902137 -4.373026488 0.827678013 1.053533859 9.69E-16 0.952975386 0.053494219 0.321569469 0.176957515 0.009187431 0.297705325 4.24E-05 4.373026488 -1.053533859 down LLGHWEEAAHDLALACK ddPTM_HeLa_Curcumin_4h_R1 2 LLGHWEEAAHDLALACK 17 0 P50502;H7C3I1;Q8IZP2 P50502 ST13;ST13P4 Hsc70-interacting protein;Putative protein FAM10A4 0 0 ; ; 99.481 0.00066422 24024000 13031.2 9929.9 11519.5 10895.8 11408.2 20430.7 13571.2 14222 13730.3 10786.4 FALSE FALSE TRUE 11999.76677 10788.19631 11946.4228 10850.71607 11272.16467 16193.14252 13951.97135 18558.22233 12224.12044 11161.2266 1.075129751 0.96657802 1.070350351 0.972179534 1.009939595 1.450838972 1.250039252 1.662740396 1.095230917 1 13.44620796 -4.584027372 0.908772437 1.024593527 1.753078134 0.777021856 0.104042168 0.445672829 0.375281853 0.015068694 0.285664975 2.61E-05 4.584027372 0.728484606 LLGLTPPEGGAGDRS(ph)EEEASSTEKPTK ddPTM_HeLa_Curcumin_4h_R1 1 LLGLTPPEGGAGDRSEEEASSTEKPTK 27 2 V9GYY5;Q9UGY1 V9GYY5 NOL12 Nucleolar protein 12 1 0 LLGLT(0.069)PPEGGAGDRS(0.793)EEEAS(0.094)S(0.021)T(0.021)EKPT(0.003)K 51.39 0.010405 62352000 1160.6 814.88 841.29 966.67 1044.8 1075 962.41 643.16 882.37 889.23 TRUE FALSE FALSE 1068.737285 885.3145962 872.4689475 962.6701757 1032.341442 852.0328823 989.4126344 839.2565233 785.5762186 920.1306763 1.161505983 0.962161809 0.94820113 1.046232019 1.121950902 0.925991171 1.075295781 0.912105796 0.853765926 1 9.845694956 -7.237099482 24.890704 1.076266724 1.00359565 0 0.101357712 1092.66155 1117389.449 0.013893172 0.017011378 5.79E-08 7.237099482 -0.072671075 LLGNS(ph)LLK ddPTM_HeLa_Curcumin_4h_R1 1 LLGNSLLK 8 0 H7BYJ3;O14578;O14578-4;O14578-3 H7BYJ3 CIT Citron Rho-interacting kinase 1 0 LLGNS(1)LLK 90.777 0.020451 3822200 1856 1625.6 2032.9 1555.7 1558.3 2085.8 1428.1 1306.2 1930.8 1640.7 TRUE FALSE FALSE 1709.095642 1766.10962 2108.241062 1549.262926 1539.71829 1653.181568 1468.168642 1704.454367 1718.996071 1697.714203 1.006703978 1.040286768 1.241811524 0.912558146 0.906936095 0.973769063 0.8647914 1.003970141 1.012535601 1 10.7293779 LLGPSLTSTT(ph)PASSSSGSSSR ddPTM_HeLa_Curcumin_4h_R1 2 LLGPSLTSTTPASSSSGSSSR 21 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 0 LLGPS(0.001)LT(0.007)S(0.029)T(0.149)T(0.619)PAS(0.117)S(0.029)S(0.006)S(0.001)GS(0.006)S(0.023)S(0.014)R;LLGPSLT(0.048)S(0.163)T(0.163)T(0.626)PASSSSGSSSR ; 129.43 6.10E-05 10342000 2284.9 2104.2 2348.2 2680 2561 4102.7 4180.2 1665.77 2373.8 2563.3 TRUE FALSE FALSE 2104.047754 2286.077672 2435.226358 2668.91087 2530.461748 3251.753773 4297.485162 2173.655605 2113.400079 2652.374484 0.79326949 0.861898531 0.918130668 1.006234559 0.954036379 1.22597838 1.620240727 0.819513088 0.79679551 1 11.37306877 -5.279677903 3.877159822 0.907468113 1.266959129 0.360200959 0.19268416 0.157288626 5.360950408 0.025754025 0.064401043 5.25E-06 5.279677903 0.359491016 LLGPVLVK ddPTM_HeLa_Curcumin_4h_R1 3 LLGPVLVK 8 0 A2AB88;O15212 A2AB88 PFDN6 Prefoldin subunit 6 0 0 ;; ;; 146.21 1.13E-13 0 5096.1 3915.3 4503.1 3718.61 3870.67 5491.3 4026.62 4365.7 4429.48 3958.37 FALSE FALSE TRUE 4692.738308 4253.721086 4669.988847 3703.223377 3824.514788 4352.34248 4139.59612 5696.781833 3943.577126 4095.923063 1.145709584 1.038525632 1.140155412 0.904124252 0.93373697 1.062603573 1.010662568 1.390842002 0.962805469 1 11.9999729 -4.257420939 24.71514563 1.049522391 1.390842159 0.64444738 0.079867161 187.1645901 1151088.198 0.011854778 0.121098419 5.53E-05 4.257420939 0.341319768 LLGQFSEK(ac)ELAAEK ddPTM_HeLa_Curcumin_4h_R1 1 LLGQFSEKELAAEK 14 1 P53004 P53004 BLVRA Biliverdin reductase A 0 1 LLGQFSEK(1)ELAAEK 202.13 8.10E-19 1024700 370.94 216.72 178.6 358.89 221.88 364.37 330.96 268.24 165.81 397.16 FALSE TRUE FALSE 341.5797076 235.4523111 185.2190731 357.4050083 219.2342259 288.7955547 340.2458469 350.0251412 147.6210578 410.9612804 0.831172482 0.572930644 0.450697138 0.869680491 0.533466865 0.702731786 0.827926773 0.851722919 0.359209164 1 8.682858664 -7.830048539 1.503493687 0.951353097 0.688708001 0 0.231586014 0.253769309 1.195235928 0.030937564 0.028843583 1.48E-08 7.830048539 -0.262645096 LLHEDLDES(ph)DDDMDEK ddPTM_HeLa_Curcumin_4h_R1 8 LLHEDLDESDDDMDEK 16 0 O43150;O43150-2 O43150 ASAP2 "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2" 1 0 LLHEDLDES(1)DDDMDEK;LLHEDLDES(1)DDDMDEK;LLHEDLDES(1)DDDMDEK;LLHEDLDES(1)DDDMDEK;LLHEDLDES(1)DDDMDEK;LLHEDLDES(1)DDDMDEK;LLHEDLDES(1)DDDMDEK;LLHEDLDES(1)DDDMDEK ;;;;;;; 231.21 6.20E-22 140312400 36983.8 32930.4 34803.1 32246.8 39965.2 33050.5 32587.8 33076.4 31324.5 30979.8 TRUE FALSE FALSE 34056.4932 35776.75704 36092.9335 32113.37129 39488.64109 26195.45374 33502.12596 43161.24209 27888.28072 32056.34574 1.062394743 1.116058497 1.125921644 1.001778916 1.231850985 0.817169055 1.045101217 1.346418037 0.869976913 1 14.96832235 -1.000000031 0.012408551 4.62E-08 2.328098615 0.154086386 0.136827955 14872.11413 14.40787557 1125.963815 1619.783012 0.099999993 1.000000031 2.328098569 LLHIEELR ddPTM_HeLa_Curcumin_4h_R1 4 LLHIEELR 8 0 Q9Y224 Q9Y224 C14orf166 UPF0568 protein C14orf166 0 0 ;;; ;;; 195.81 0.00025984 64534000 14925.4 12738.9 14085 12683.6 13410.5 17558.4 13136.8 13881.1 14609.5 13190.2 FALSE FALSE TRUE 13744.03884 13839.99375 14607.00249 12631.11862 13250.58855 13916.58992 13505.38325 18113.38349 13006.8744 13648.55847 1.006995638 1.014026044 1.070223095 0.92545441 0.970841615 1.019638077 0.989509865 1.327127955 0.952985213 1 13.73646096 -4.260149044 24.98299569 1.001586398 1.327128061 0.872646195 0.038042899 24.13714154 467280.7469 0.004557148 0.038088927 5.49E-05 4.260149044 0.325541663 FELLPTPPLS(ph)PSRR ddPTM_HeLa_Curcumin_4h_R1 1 FELLPTPPLSPSRR 14 1 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1 H0YBT0 MYC Myc proto-oncogene protein 1 0 FELLPT(0.183)PPLS(0.78)PS(0.037)RR 113.65 0.0038061 12273000 1973.8 1660.7 1294.7 1628.3 1379.8 2126 867.89 360.2 2274.9 1539.1 TRUE FALSE FALSE 1817.571647 1804.243508 1342.682721 1621.562526 1363.346786 1685.043635 892.2406576 470.0233218 2025.349162 1592.58361 1.141272355 1.132903476 0.843084603 1.018196166 0.856059787 1.058056622 0.560247294 0.295132588 1.271738041 1 10.6371534 -4.372609068 1.194574825 1.04823323 4.55E-12 0.788517871 0.128677242 0.365513597 0.491674186 0.016648938 0.449504724 4.24E-05 4.372609068 -1.04823323 down LLHPS(ph)PDLVSQEATLSEAR ddPTM_HeLa_Curcumin_4h_R1 4 LLHPSPDLVSQEATLSEAR 19 0 A0A087WU05;A0A087WY48;Q8IY22-3;Q8IY22-2;Q8IY22 A0A087WU05 CMIP C-Maf-inducing protein 1 0 LLHPS(1)PDLVSQEATLSEAR;LLHPS(1)PDLVSQEATLSEAR;LLHPS(1)PDLVSQEATLSEAR;LLHPS(0.98)PDLVS(0.012)QEAT(0.005)LS(0.003)EAR ;;; 183.76 8.54E-08 49988000 14346.23 10846.25 11715.32 11707.03 12674.09 14835.27 10219.73 6089.96 14590.67 11902.63 TRUE FALSE FALSE 13210.71076 11783.75152 12149.50007 11658.58941 12522.95975 11758.26777 10506.46812 7946.760769 12990.11001 12316.24551 1.072624831 0.95676491 0.986461342 0.946602551 1.016783869 0.954695793 0.853057704 0.645225914 1.054713468 1 13.58827491 -3.703612709 0.817710161 1.022283096 2.20E-14 0.896959079 0.037522483 1.258040454 0.324728442 0.006948961 1.445793627 0.000197873 3.703612709 -1.022283096 LLIDGDGAGDDRR ddPTM_HeLa_Curcumin_4h_R1 3 LLIDGDGAGDDRR 13 1 H7C5E3;Q6I9Y2 H7C5E3 THOC7 THO complex subunit 7 homolog 0 0 ;; ;; 121.29 0.0034991 13595800 7050.9 5704.8 6043.4 6479.8 6758.4 7080.5 5470.99 5579 7528.4 6362.7 FALSE FALSE TRUE 6492.813825 6197.897492 6267.37372 6452.988305 6677.810494 5611.924486 5624.491255 7280.011417 6702.553355 6583.803351 0.986179793 0.941385573 0.951938171 0.980130779 1.014278547 0.85238337 0.85429211 1.105745574 1.018036688 1 12.68470553 -7.42204763 0.751641043 0.998229672 0.948848553 0.064933648 0.069947741 1.172898056 1.39827401 0.018424236 0.019767382 3.78E-08 7.42204763 -0.049381119 LLIQISAEYDPSK ddPTM_HeLa_Curcumin_4h_R1 1 LLIQISAEYDPSK 13 0 A0A0G2JQE0;A0A0G2JNC7;A0A0G2JS53;Q13075-2;Q13075 A0A0G2JQE0 NAIP Baculoviral IAP repeat-containing protein 1 0 0 130.66 0.013703 11936000 2462.5 1807.6 2000.3 2043 1814 3103.1 2266.2 2285.9 2350 1936.8 FALSE FALSE TRUE 2267.590527 1963.840889 2074.432878 2034.546607 1792.369235 2459.482081 2329.783473 2982.860387 2092.210879 2004.103656 1.131473674 0.979909838 1.035092607 1.015190308 0.894349566 1.22722299 1.162506473 1.488376301 1.043963406 1 10.96874141 -4.015005825 1.177207662 1.044835506 1.898667973 0.7579997 0.078267343 1.019877105 0.794093754 0.012454971 1.221013453 9.66E-05 4.015005825 0.853832467 LLIVSTTPYSEK ddPTM_HeLa_Curcumin_4h_R1 1 LLIVSTTPYSEK 12 0 Q9Y230;Q9Y230-2;M0R0Y3 Q9Y230 RUVBL2 RuvB-like 2 0 0 119.27 0.0011434 471990 432.15 378.02 496.49 454.83 448.87 506.19 383.23 456.58 305.97 246.95 FALSE FALSE TRUE 397.9448715 410.6943644 514.8903562 452.948034 443.5175184 401.2004881 393.9824024 595.7891402 272.4058565 255.5314941 1.557322211 1.607216229 2.014978067 1.772572244 1.735666752 1.57006278 1.541815437 2.331568335 1.066036331 1 7.997357303 -8.583615699 0.436522285 0.906958324 1.82729375 0.653806297 0.220385705 0.60443547 0.223998667 0.24311567 0.078763378 2.61E-09 8.583615699 0.920335427 LLKEGEEPTVYS(ph)DEEEPKDESAR ddPTM_HeLa_Curcumin_4h_R1 4 LLKEGEEPTVYSDEEEPKDESAR 23 2 O00264-2;O00264 O00264-2 PGRMC1 Membrane-associated progesterone receptor component 1 1 0 LLKEGEEPT(0.002)VY(0.045)S(0.953)DEEEPKDESAR;LLKEGEEPT(0.001)VY(0.042)S(0.957)DEEEPKDESAR;LLKEGEEPT(0.01)VY(0.249)S(0.741)DEEEPKDESAR;LLKEGEEPT(0.007)VY(0.42)S(0.573)DEEEPKDESAR ;;; 115.91 1.29E-06 580173000 8024.8 7275.6 8288 12222.3 7794.4 10689.8 4644.19 3432.36 15341.5 10746.1 TRUE FALSE FALSE 7389.628612 7904.470445 8595.160571 12171.72736 7701.456871 8472.614981 4774.493472 4478.870763 13658.57583 11119.52618 0.664563264 0.710863963 0.772979031 1.094626441 0.692606569 0.761958275 0.42937922 0.402793311 1.228341533 1 13.44080769 -4.802778159 2.095125346 0.833873171 0.378577579 0.498441143 0.179102777 0.207878029 1.718692787 0.02275942 0.118455299 1.57E-05 4.802778159 -0.455295593 LLKPGEEPSEY(ph)TDEEDTKDHNKQD ddPTM_HeLa_Curcumin_4h_R1 1 LLKPGEEPSEYTDEEDTKDHNKQD 24 3 U3KPU8;U3KQM0;O15173;O15173-2 U3KPU8 PGRMC2 Membrane-associated progesterone receptor component 2 1 0 LLKPGEEPS(0.033)EY(0.512)T(0.436)DEEDT(0.018)KDHNKQD 45.659 0.0097337 93740000 5896.3 4739.5 5435.8 7478.9 5106.8 5224.7 3052.5 1550.9 9620.3 6852.6 TRUE FALSE FALSE 5429.601633 5149.161261 5637.25553 7447.954293 5045.904745 4141.038325 3138.144935 2023.762271 8564.977159 7090.72734 0.765732678 0.726182381 0.795017952 1.050379451 0.711620191 0.584007553 0.442570245 0.285409687 1.207912355 1 12.79171791 -4.977122088 1.28785507 0.87588855 0.289447992 0.697920372 0.145846926 0.214904082 0.589382728 0.018775461 0.117101281 1.05E-05 4.977122088 -0.586440558 THS(ph)DASDDEAFTTSK ddPTM_HeLa_Curcumin_4h_R1 1 THSDASDDEAFTTSK 15 0 Q13017-2;Q13017;H0YK04 Q13017-2 ARHGAP5 Rho GTPase-activating protein 5 1 0 THS(0.928)DAS(0.072)DDEAFTTSK 150.12 0.00044281 16924000 2104.1 1827.9 1729.2 2071.8 2219 2765.8 1624.8 721.91 2403.4 2226.8 TRUE FALSE FALSE 1937.558265 1985.895531 1793.285673 2063.227441 2192.539874 2192.141903 1670.387515 942.0170357 2139.753033 2304.181134 0.840888 0.861866067 0.77827461 0.895427625 0.951548401 0.951375684 0.724937589 0.40882942 0.928639247 1 11.17003842 -4.372480492 2.449340395 0.909498869 0.355922225 0.854445161 0.062044743 0.137833227 1.185121634 0.011217091 0.142785999 4.24E-05 4.372480492 -0.553576644 down LLLAEDS(ph)EEEVDFLSER ddPTM_HeLa_Curcumin_4h_R1 4 LLLAEDSEEEVDFLSER 17 0 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 LLLAEDS(1)EEEVDFLSER;LLLAEDS(1)EEEVDFLSER;LLLAEDS(1)EEEVDFLSER;LLLAEDS(1)EEEVDFLSER ;;; 254.72 1.70E-40 573337000 19361.56 13720.26 16807.822 21462.57 17914.22 21246.19 16400.75 8943.11 20180.6 17007.8 TRUE FALSE FALSE 17829.0721 14906.17814 17430.73467 21373.76357 17700.60463 16839.4907 16860.9109 11669.82307 17966.83867 17598.81978 1.013083395 0.846998737 0.990449069 1.214499826 1.005783618 0.956853409 0.958070547 0.663102595 1.020911566 1 14.10319106 -4.01642303 1.710961506 1.006987641 0.337168555 0.593827626 0.084637447 1.047992696 1.765431833 0.01205443 1.397228534 9.63E-05 4.01642303 -0.669819086 LLLAEDS(ph)EEEVDFLSERR ddPTM_HeLa_Curcumin_4h_R1 3 LLLAEDSEEEVDFLSERR 18 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 LLLAEDS(1)EEEVDFLSERR;LLLAEDS(1)EEEVDFLSERR;LLLAEDS(1)EEEVDFLSERR ;; 98.804 0.00076971 17102500 3926.7 2377.59 3122.59 3804.18 2709.84 4514.1 3104.29 2035.54 5580.9 4316.5 TRUE FALSE FALSE 3615.897552 2583.098285 3238.315932 3788.439311 2677.526928 3577.824776 3191.388023 2656.166776 4968.689233 4466.498054 0.809559863 0.578327418 0.725023473 0.848190073 0.599468957 0.801035785 0.714516828 0.594686652 1.112435105 1 12.12492842 -8.294371964 0.666069761 0.990639515 0.698556529 0.658987689 0.09767479 0.312178742 0.300133668 0.041354837 0.022053357 5.08E-09 8.294371964 -0.292082986 ETDYPAGEDLSES(ph)GQVDK ddPTM_HeLa_Curcumin_4h_R1 1 ETDYPAGEDLSESGQVDK 18 0 O60271-3;O60271;A0A087X2D8;O60271-5;O60271-9;O60271-4;O60271-2;H0YBS5 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 ETDYPAGEDLSES(1)GQVDK 346.37 3.89E-153 11157000 3571.3 2955.1 2927.2 3254.4 3471 3508.5 2141.4 766.1 2649.9 2572.7 TRUE FALSE FALSE 3288.627837 3210.525676 3035.684607 3240.934155 3429.610592 2780.797551 2201.481921 999.6803633 2359.2126 2662.101134 1.235350451 1.206011911 1.140334065 1.217434648 1.288309655 1.044587494 0.826971558 0.37552306 0.886222003 1 11.37834967 -4.372432863 1.762010746 1.141630867 0.220754043 0.809117339 0.11375347 0.211440296 0.769754831 0.015840172 0.300413764 4.24E-05 4.372432863 -0.920876824 down LLLDDS(ph)FETK ddPTM_HeLa_Curcumin_4h_R1 1 LLLDDSFETK 10 0 O00443;A0A0C4DGF9;O00443-2;E9PPP3 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 0 LLLDDS(0.998)FET(0.002)K 142.76 0.0013306 3268200 2022 1784.5 1624 1669.5 1822.8 2785.5 2142.3 1020.5 1831.6 1835.6 TRUE FALSE FALSE 1861.956566 1938.744228 1684.186869 1662.592051 1801.064301 2207.755901 2202.407172 1331.645752 1630.678062 1899.386963 0.980293433 1.020721036 0.886700236 0.875330874 0.948234528 1.162351824 1.159535795 0.701092393 0.858528617 1 10.89131814 -4.23870154 24.17784222 0.99495405 0.70109189 0.417237493 0.10140844 2818.521409 2996949.968 0.013029259 0.899988068 5.77E-05 4.23870154 -0.29386216 LLLDDSFET(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 LLLDDSFETK 10 0 O00443;A0A0C4DGF9;O00443-2;E9PPP3 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 0 LLLDDS(0.361)FET(0.639)K 127.83 0.0070871 0 1075.8 894.12 1038.8 1016.9 1116.2 1804.1 1241.6 756.16 845.62 1093.6 TRUE FALSE FALSE 990.6492948 971.4037487 1077.298842 1012.692337 1102.890044 1429.909324 1276.435954 986.7097031 752.8576016 1131.602519 0.875439281 0.858431943 0.952011704 0.894918773 0.974626714 1.263614476 1.127989673 0.871957853 0.665302162 1 10.14415158 -5.504595182 24.42751055 0.931079662 1.09640976 0.305179352 0.128390172 464.6072043 620731.2637 0.014249493 0.031297151 3.13E-06 5.504595182 0.165330098 LLLDIPLQT(ph)PHK ddPTM_HeLa_Curcumin_4h_R1 1 LLLDIPLQTPHK 12 0 P49792;J3KNE0;J3KQ37;A6NKT7;Q99666;O14715;F8VYC4;P0DJD0;P0DJD1;A0A1W2PNU4;A0A286YES2 P49792 RANBP2;RGPD3;RGPD8;RGPD5;RGPD1;RGPD2 E3 SUMO-protein ligase RanBP2;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2 1 0 LLLDIPLQT(1)PHK 110.55 0.0051463 12771000 2544.2 3223.9 3788.8 4313.6 3833.5 6330 7547.8 4193 3237.1 2901.3 TRUE FALSE FALSE 2342.823885 3502.559551 3929.216261 4295.751466 3787.788016 5017.086646 7759.570954 5471.426398 2881.998229 3002.119959 0.78038983 1.166695401 1.308813876 1.430906001 1.261704418 1.67118127 2.584697167 1.822520909 0.959987698 1 11.55176591 -5.354091614 0.638748767 0.905312393 2.378609879 0.735003125 0.256146018 0.418230986 0.240620578 0.049592625 0.349415119 4.42E-06 5.354091614 1.473297485 LLLDIPLQT(ph)PHKLVDTGR ddPTM_HeLa_Curcumin_4h_R1 1 LLLDIPLQTPHKLVDTGR 18 1 P49792;J3KNE0;J3KQ37;A6NKT7;Q99666;O14715;F8VYC4;P0DJD0;P0DJD1;A0A1W2PNU4;A0A286YES2 P49792 RANBP2;RGPD3;RGPD8;RGPD5;RGPD1;RGPD2 E3 SUMO-protein ligase RanBP2;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2 1 0 LLLDIPLQT(0.762)PHKLVDT(0.238)GR 49.463 0.01761 12036000 6509.3 5227.3 6222.6 6997.1 5549.1 12187 12882 7837.1 7271 6712.3 TRUE FALSE FALSE 5994.082036 5679.12452 6453.21503 6968.147854 5482.930607 9659.278824 13243.43425 10226.59571 6473.389491 6945.551925 0.863010183 0.817663532 0.929114792 1.003253295 0.789416113 1.390714363 1.906750449 1.472394969 0.932019451 1 12.76187363 -5.067220995 3.999903587 0.92237882 1.687910054 0.876985626 0.120586736 0.048668409 1.511367034 0.016210374 0.045984372 8.57E-06 5.067220995 0.765531234 LLLIGDSGVGK ddPTM_HeLa_Curcumin_4h_R1 2 LLLIGDSGVGK 11 0 P61006;A0A2R8YDI9;E9PLD0;G3V196;H0YLJ8;H0YNE9;E7END7;A0A2R8YFB8;H0YMN7;H0YL94;P62820-2;P62820-3;P61026;Q92928;P51153;P62820;Q92930;P61006-2;P59190-2;P59190;Q9H0U4 P61006 RAB8A;RAB1B;RAB15;RAB8B;RAB1A;RAB10;RAB1C;RAB13 Ras-related protein Rab-8A;Ras-related protein Rab-1A;Ras-related protein Rab-10;Putative Ras-related protein Rab-1C;Ras-related protein Rab-13;Ras-related protein Rab-8B;Ras-related protein Rab-15;Ras-related protein Rab-1B 0 0 ; ; 143.03 2.24E-05 1793400 3830.3 3492.1 3874.8 4091 3415.2 5736.2 4226.7 2682.3 4441.3 4022.3 FALSE FALSE TRUE 3527.127713 3793.941564 4018.403497 4074.072526 3374.475971 4546.44746 4345.289826 3500.120922 3954.100502 4162.074626 0.847444611 0.911550586 0.965480886 0.978856194 0.810767772 1.09235126 1.044020162 0.84095583 0.95003114 1 12.02308712 -5.251752556 24.98458805 0.925189556 0.997600175 0.130884858 0.081061639 1141.377509 2943871.069 0.012298594 0.030905882 5.60E-06 5.251752556 0.072410618 LLLNNDNLLR ddPTM_HeLa_Curcumin_4h_R1 2 LLLNNDNLLR 10 0 C9JUG7;F8W9N7;P47755-2;P47755;A0A0D9SET8;P52907 C9JUG7;P52907 CAPZA2;CAPZA1 F-actin-capping protein subunit alpha-2;F-actin-capping protein subunit alpha-1 0 0 ; ; 138.06 0.00035425 3668300 3118.5 2687.4 2796.3 2559.37 2901.95 4158.2 3265.3 3007.6 2886.1 2307.8 FALSE FALSE TRUE 2871.667434 2919.686881 2899.933338 2548.780005 2867.346142 3295.742447 3356.91553 3924.603395 2569.502051 2387.995878 1.202542877 1.222651558 1.214379541 1.067330153 1.200733288 1.380129035 1.405745948 1.643471595 1.076007741 1 11.22158463 -1 0.315842488 1.076229408 6.237684891 0.845206933 0.071264439 16.5986924 0.211883102 0.030610992 49.95362146 0.1 1 5.161455484 LLLPGELAK ddPTM_HeLa_Curcumin_4h_R1 2 LLLPGELAK 9 0 P33778;P58876;P62807;P57053;O60814;Q16778;P06899;Q5QNW6;Q5QNW6-2;Q8N257;Q93079;U3KQK0;Q99877;Q99879;Q99880 P33778;P58876;P62807;Q16778;Q5QNW6;Q8N257;Q93079;U3KQK0;Q99879;Q99880 HIST1H2BB;HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST2H2BF;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BM;HIST1H2BL Histone H2B type 1-B;Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 2-F;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-M;Histone H2B type 1-L 0 0 ; ; 123.72 0.0010692 265230000 23479.6 16855.1 20060.3 19072.4 19301.9 21777.5 18969.1 18763.1 18042.4 15998.6 FALSE FALSE TRUE 21621.16488 18311.97974 20803.75236 18993.48346 19071.73745 17260.60102 19501.32189 24483.88282 16063.19386 16554.55016 1.306055717 1.106159912 1.256678808 1.147327066 1.152054104 1.042649957 1.178003733 1.478982067 0.970318958 1 14.01494019 -9.516063397 1.249859906 0.999229023 1.208854349 0.371637405 0.115166908 0.454820295 1.264353447 0.081714087 0.019363285 3.05E-10 9.516063397 0.209625326 LLNGNHENGDLDPT(ph)SPLENMDYIK ddPTM_HeLa_Curcumin_4h_R1 3 LLNGNHENGDLDPTSPLENMDYIK 24 0 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4;F5H6X8;F5H221;F8WE35;F5H8I0;F5H592;F5H2W9;F5H2H9;F5GZ10;F5H502;F5H1K9;A8MV73 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 0 LLNGNHENGDLDPT(0.484)S(0.484)PLENMDY(0.033)IK;LLNGNHENGDLDPT(0.495)S(0.495)PLENMDY(0.011)IK;LLNGNHENGDLDPT(0.492)S(0.492)PLENMDY(0.016)IK ;; 83.871 0.00019824 12927100 3503.69 2886.32 2853.77 2847.92 3473.22 3595.82 3475.28 3873.74 2853.36 2865.16 TRUE FALSE FALSE 3226.369239 3135.80064 2959.533227 2836.136062 3431.80412 2850.006399 3572.787004 5054.825493 2540.353547 2964.724097 1.08825278 1.057704035 0.998249122 0.956627318 1.157545865 0.961305776 1.205099324 1.704990187 0.856860019 1 11.53368214 -4.29423741 2.687659767 1.038523627 1.809926531 0.86533963 0.08218138 0.077169063 0.769600954 0.008119445 0.127551302 5.08E-05 4.29423741 0.771402904 LLNLQDS(ph)DSEECTSR ddPTM_HeLa_Curcumin_4h_R1 1 LLNLQDSDSEECTSR 15 0 Q52LR7 Q52LR7 EPC2 Enhancer of polycomb homolog 2 1 0 LLNLQDS(0.952)DS(0.046)EECT(0.001)S(0.001)R 142.55 0.00051555 10037000 1727.2 1603.5 1532.5 1791 1786.3 1941.1 1230 1108.4 2171.8 1573.6 TRUE FALSE FALSE 1590.490297 1742.099395 1589.295798 1783.589317 1764.999539 1538.493979 1264.51049 1446.346058 1933.558974 1628.282483 0.976790154 1.069899979 0.976056559 1.095380768 1.083963967 0.944856925 0.776591594 0.888264827 1.187483741 1 10.66913529 -4.949362282 5.512422263 1.007983642 0.835247805 0.528289539 0.076088197 0.086879629 5.837460676 0.007335371 0.02253192 1.12E-05 4.949362282 -0.172735837 LLNLQDSDS(ph)EECTSR ddPTM_HeLa_Curcumin_4h_R1 2 LLNLQDSDSEECTSR 15 0 Q52LR7 Q52LR7 EPC2 Enhancer of polycomb homolog 2 1 0 LLNLQDS(0.222)DS(0.732)EECT(0.04)S(0.005)R;LLNLQDS(0.309)DS(0.691)EECTSR ; 172.56 0.00013667 24504000 2360.2 1885.17 2219.55 2189.5 1960.54 2067.63 1802.76 1260.5 2368.9 2108.28 TRUE FALSE FALSE 2173.38768 2048.115695 2301.808476 2180.440429 1937.161841 1638.780231 1853.340594 1644.820647 2109.037597 2181.542573 0.996261868 0.938838288 1.055128836 0.999494787 0.887978014 0.751202498 0.849555088 0.753971372 0.966764354 1 11.09113291 -5.562034572 3.144014124 0.998070138 0.792209266 0.855631527 0.038257655 0.057364578 1.160436218 0.00495627 0.011002079 2.74E-06 5.562034572 -0.205860873 LLPAAS(ph)SDAESGTGSSDREPPR ddPTM_HeLa_Curcumin_4h_R1 1 LLPAASSDAESGTGSSDREPPR 22 1 Q9Y4B5 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 0 LLPAAS(0.497)S(0.497)DAES(0.002)GT(0.002)GS(0.002)S(0.001)DREPPR 59.585 0.0045006 15702000 1280.2 1147.7 1233.1 1244.4 1416.1 1235.9 711.86 437.55 1292.3 1045.5 TRUE FALSE FALSE 1178.870819 1246.902074 1278.799771 1239.251003 1399.213932 979.5604085 731.8328757 570.9569808 1150.537923 1081.831047 1.089699563 1.152584849 1.182069764 1.145512514 1.293375649 0.90546524 0.676476126 0.527769084 1.063509802 1 10.07925949 -4.806160626 2.664369783 1.085227612 0.564811551 0.84860131 0.088062829 0.090152735 1.257417401 0.014522297 0.062969687 1.56E-05 4.806160626 -0.520416062 ASVVDPSTESSPAPQEGSEQPASPAS(ph)PLSSR ddPTM_HeLa_Curcumin_4h_R1 2 ASVVDPSTESSPAPQEGSEQPASPASPLSSR 31 0 Q66K14;Q66K14-2 Q66K14 TBC1D9B TBC1 domain family member 9B 1 0 ASVVDPSTESSPAPQEGSEQPAS(0.092)PAS(0.779)PLS(0.064)S(0.064)R;ASVVDPSTESSPAPQEGSEQPAS(0.009)PAS(0.688)PLS(0.091)S(0.212)R ; 147.37 4.73E-13 16198200 8191.3 6295.6 7296.1 7189.3 6920.4 7194.6 4888.6 2502.28 8115 6892.5 TRUE FALSE FALSE 7542.949962 6839.763611 7566.499884 7159.552582 6837.87875 5702.35886 5025.760959 3265.213653 7224.804803 7132.013862 1.057618522 0.959022759 1.060920524 1.003861282 0.958758477 0.799543996 0.704676275 0.457824917 1.013010482 1 12.80009379 -4.370267551 0.830583395 1.02688474 0.198437499 0.967138866 0.03317765 0.248556004 0.137552664 0.005574658 0.181638454 4.26E-05 4.370267551 -0.828447241 down LLPEGEETLES(ph)DDEKDEHTSK ddPTM_HeLa_Curcumin_4h_R1 2 LLPEGEETLESDDEKDEHTSK 21 1 Q8N6N3 Q8N6N3 C1orf52 UPF0690 protein C1orf52 1 0 LLPEGEET(0.014)LES(0.98)DDEKDEHT(0.004)S(0.002)K;LLPEGEET(0.026)LES(0.972)DDEKDEHT(0.002)S(0.001)K ; 60.618 0.0042043 217155000 10743.6 10458.1 9604.8 9172 16442.7 28683 13655.6 12029.7 17061.4 10954.4 TRUE FALSE FALSE 9893.232723 11362.05156 9960.762337 9134.048694 16246.63154 22733.82248 14038.73938 15697.50015 15189.80711 11335.06458 0.872798973 1.00238084 0.878756558 0.805822378 1.433307364 2.005619139 1.238523105 1.384861995 1.340072391 1 13.46850499 -5.682368369 5.63506312 0.930620054 1.542221749 0.555217437 0.231343138 0.085208638 4.556582029 0.027193967 0.054750272 2.08E-06 5.682368369 0.611601695 LLPPAS(ph)P ddPTM_HeLa_Curcumin_4h_R1 4 LLPPASP 7 0 Q9Y4R8 Q9Y4R8 TELO2 Telomere length regulation protein TEL2 homolog 1 0 LLPPAS(1)P;LLPPAS(1)P;LLPPAS(1)P;LLPPAS(1)P ;;; 120.62 0.00704 55238800 9579.12 8397.58 8589.12 9410.27 8880.98 9679.16 7650.65 7410.8 10198.62 9704.65 TRUE FALSE FALSE 8820.922544 9123.429396 8907.440343 9371.332796 8775.080114 7671.593109 7865.306648 9670.318805 9079.856902 10041.88587 0.878412946 0.908537452 0.887028638 0.933224389 0.873847824 0.763959401 0.783249955 0.962998279 0.904198377 1 13.29374261 -13.52287871 0.158239653 1.518196444 0.826853839 0.13565636 0.064092776 43.32625049 0.459266475 6.922339374 0.114956062 3.00E-14 13.52287871 -0.691342604 LLPPVGTGRS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 LLPPVGTGRSPR 12 1 Q9NWZ5;Q9NWZ5-3;Q9NWZ5-2;Q9NWZ5-4 Q9NWZ5;Q9NWZ5-4 UCKL1 Uridine-cytidine kinase-like 1 1 0 LLPPVGT(0.018)GRS(0.982)PR;LLPPVGT(0.003)GRS(0.997)PR ; 97.223 0.0047444 119562000 9768.7 8134.9 8648.1 9288.1 7557 9056.7 7483 5976.6 9601.2 10002.3 TRUE FALSE FALSE 8995.497087 8838.044508 8968.606194 9249.668303 7466.887711 7178.23833 7692.952841 7798.837827 8547.972381 10349.87918 0.869140299 0.853927312 0.866542115 0.893698191 0.721446848 0.693557693 0.743289144 0.753519697 0.825900692 1 13.33732631 -5.762618934 0.120411227 1.137286397 0.453545429 0.41193267 0.068400163 5.94727158 0.227815717 0.396489241 0.911062132 1.73E-06 5.762618934 -0.683740968 LLPSAPQTLPDGPLAS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 4 LLPSAPQTLPDGPLASPAR 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;X6RGP5;A0A0C4DH09;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 LLPSAPQTLPDGPLAS(1)PAR;LLPS(0.001)APQTLPDGPLAS(0.999)PAR;LLPSAPQTLPDGPLAS(1)PAR;LLPS(0.003)APQT(0.015)LPDGPLAS(0.982)PAR ;;; 214.3 3.13E-18 342539000 15271.7 12442 14383.5 14725.3 15762.5 13930.6 8795.45 5695.41 14153.5 11643.13 TRUE FALSE FALSE 14062.92883 13517.43104 14916.56516 14664.37061 15574.54248 11041.23653 9042.226655 7431.914291 12600.89646 12047.7279 1.167268131 1.121990067 1.238122681 1.217189725 1.292736905 0.916457993 0.750533771 0.616872688 1.045914762 1 13.55647347 -4.866886052 2.654974794 1.119012727 0.660135563 0.802405914 0.09293044 0.109040381 1.513432091 0.015876271 0.063957049 1.36E-05 4.866886052 -0.458877164 KGWSMS(ph)EQSEESVGGR ddPTM_HeLa_Curcumin_4h_R1 1 KGWSMSEQSEESVGGR 16 1 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 KGWS(0.023)MS(0.977)EQSEESVGGR 139.32 0.0010369 11314000 2113.6 1176.2 1303.5 1733.5 1519.8 4289.8 5602.8 8162.6 1864.2 1417.3 TRUE FALSE FALSE 1946.30633 1277.865487 1351.808857 1726.327236 1501.677378 3400.047124 5759.999489 10651.33916 1659.701924 1466.55107 1.327131643 0.871340599 0.921760507 1.177134075 1.023951643 2.318396675 3.927581936 7.262849133 1.131704145 1 10.5182116 -4.256015458 1.190842254 1.099064124 10.2576156 0.991298941 0.181103846 0.107837714 0.123342974 0.030947339 1.224156807 5.55E-05 4.256015458 9.158551472 up LLPYPTLAS(ph)PASD ddPTM_HeLa_Curcumin_4h_R1 1 LLPYPTLASPASD 13 0 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 0 LLPYPTLAS(0.992)PAS(0.008)D 92.112 0.011088 1598800 2167.5 1759.4 1865.1 1808.2 2025.4 1334.3 1155.4 1400.6 1787 1486.9 TRUE FALSE FALSE 1995.940088 1911.474696 1934.222247 1800.718148 2001.248428 1057.551139 1187.817414 1827.636492 1590.970571 1538.569664 1.297269883 1.242371236 1.257156105 1.170384539 1.300720061 0.687359932 0.77202706 1.187880234 1.034058196 1 10.58737405 -5.267885624 24.99041847 1.171782031 0.871382872 0.447196875 0.153957564 377.0723169 1461813.383 0.023999177 0.054885202 5.40E-06 5.267885624 -0.300399159 LLPYPTLASPAS(ph)D ddPTM_HeLa_Curcumin_4h_R1 2 LLPYPTLASPASD 13 0 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 0 LLPYPTLASPAS(1)D;LLPYPTLASPAS(1)D ; 131.83 0.0015301 23569000 5552.1 4674.3 4690.8 5331.7 5135.3 6637.4 6721 5117.8 6013.8 5392 TRUE FALSE FALSE 5112.645426 5078.325664 4864.645174 5309.638838 5074.064901 5260.728421 6909.573171 6678.193661 5354.101186 5579.371599 0.916347896 0.910196708 0.871898401 0.951655351 0.909433045 0.942889056 1.238414228 1.196943696 0.959624411 1 12.44588693 -4.763867914 24.99953023 0.944565404 1.217679028 0.910199079 0.035644033 14.9829532 154244.0945 0.006415769 0.020670203 1.72E-05 4.763867914 0.273113624 LLQAQGVEVPSKDS(ph)LPK ddPTM_HeLa_Curcumin_4h_R1 2 LLQAQGVEVPSKDSLPK 17 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 0 LLQAQGVEVPS(0.195)KDS(0.805)LPK;LLQAQGVEVPS(0.165)KDS(0.835)LPK ; 87.519 0.002426 51322000 3093.9 2347.95 2739.3 2971.6 3012.7 3667.8 2616.3 2156.89 3262.5 2517.9 TRUE FALSE FALSE 2849.01455 2550.896336 2840.820868 2959.304307 2976.77552 2907.056935 2689.706337 2814.515832 2904.611912 2605.396838 1.093505031 0.979081689 1.090360143 1.135836301 1.142542079 1.115782783 1.032359561 1.080263778 1.114844338 1 11.34728742 -10.43137291 0.321385526 0.91151038 1.094005097 0 0.057828089 6.792873129 0.499945435 0.488780544 0.021003577 3.70E-11 10.43137291 0.182494717 LLQDFFNGK ddPTM_HeLa_Curcumin_4h_R1 1 LLQDFFNGK 9 0 P11142;E9PKE3;E9PNE6;P11142-2;E9PN89;A8K7Q2;P17066;P54652 P11142;P17066;P54652 HSPA8;HSPA6;HSPA2 Heat shock cognate 71 kDa protein;Heat shock 70 kDa protein 6;Heat shock-related 70 kDa protein 2 0 0 149.72 0.014634 23350000 3093 2616 2874.6 2780.8 2637.5 3403.6 2653.5 2734.8 2587.9 2752.8 FALSE FALSE TRUE 2848.185786 2842.115383 2981.135205 2769.293786 2606.049535 2697.654994 2727.950068 3568.627931 2304.013845 2848.459595 0.999903875 0.997772757 1.046578021 0.972207502 0.914897841 0.94705749 0.957693089 1.252827295 0.808863095 1 11.47596623 -4.257180278 24.9806339 0.989756723 1.2528274 0.606047511 0.067071934 133.7998649 784737.8892 0.005256264 0.05455367 5.53E-05 4.257180278 0.263070677 LLQDFFNGR ddPTM_HeLa_Curcumin_4h_R1 2 LLQDFFNGR 9 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 0 ; ; 149.72 9.61E-08 0 7642.4 5145 5919.3 5349.4 6407.3 8868 6866.9 6544.1 6269.6 6197.1 FALSE FALSE TRUE 7037.495976 5589.710874 6138.674465 5327.2656 6330.897132 7028.676837 7059.566733 8539.365965 5581.840566 6412.448764 1.097474028 0.87169677 0.957305811 0.830769305 0.987282295 1.096098713 1.100915889 1.331685644 0.870469422 1 12.64665968 -4.120768382 1.359331806 1.009104835 1.546626358 0.573495062 0.092527874 1.118743453 1.412742547 0.013994041 0.899714506 7.57E-05 4.120768382 0.537521523 LLQDSSS(ph)PVDLAK ddPTM_HeLa_Curcumin_4h_R1 1 LLQDSSSPVDLAK 13 0 E7EWM1;Q15596 E7EWM1 NCOA2 Nuclear receptor coactivator 2 1 0 LLQDS(0.002)S(0.225)S(0.773)PVDLAK 222.55 4.84E-14 27072000 5034.2 3873.2 4474 5190 4451.5 5523.9 5248.9 1274.2 5501.4 4581.5 TRUE FALSE FALSE 4635.737758 4207.982149 4639.810376 5168.525155 4398.41877 4378.180873 5396.170007 1662.697714 4897.910184 4740.706784 0.977857937 0.887627592 0.978717011 1.090243584 0.927798105 0.923529143 1.138262764 0.350727811 1.03316033 1 12.21088645 -4.25304273 24.97290711 0.987464882 0.35072749 0.874995911 0.073029382 237.880751 707477.5259 0.009035596 0.1388843 5.58E-05 4.25304273 -0.636737392 LLQLVEDRGS(ph)GR ddPTM_HeLa_Curcumin_4h_R1 1 LLQLVEDRGSGR 12 1 P17844-2;P17844;J3KTA4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 1 0 LLQLVEDRGS(1)GR 78.902 0.011244 4180200 1206.7 865.84 816.95 1050.1 939.91 1930.8 1397.8 1063.3 1126.3 866.33 TRUE FALSE FALSE 1111.188422 940.6793515 847.2268857 1045.754964 928.7021871 1530.330315 1437.018506 1387.495275 1002.747708 896.434903 1.239563986 1.049356008 0.945106982 1.166571004 1.035995122 1.70712933 1.60303721 1.547792562 1.11859512 1 9.808055012 -5.263313817 24.99965228 1.097389862 1.617691469 0.887543611 0.087920635 47.73746966 636686.7707 0.015649684 0.036758382 5.45E-06 5.263313817 0.520301607 LLQTTNNS(ph)PMNSKPQQIK ddPTM_HeLa_Curcumin_4h_R1 2 LLQTTNNSPMNSKPQQIK 18 1 O00178;B0QY59 O00178 GTPBP1 GTP-binding protein 1 1 0 LLQT(0.008)T(0.037)NNS(0.954)PMNS(0.001)KPQQIK;LLQT(0.002)T(0.008)NNS(0.99)PMNSKPQQIK ; 136.46 0.00012549 100588000 6855.1 5237.4 5911.3 6790.9 5995.9 7486 6083.2 4521.6 6969.4 6168.4 TRUE FALSE FALSE 6312.511602 5690.097519 6130.377978 6762.801055 5924.402809 5933.319215 6253.87822 5900.215025 6204.874257 6382.751441 0.988995367 0.891480355 0.960460083 1.059543226 0.928189491 0.929586444 0.979809143 0.924399936 0.972131582 1 12.63996275 -1.000000007 0.050604153 1.090596291 0.736677912 0.039263076 0.044561602 596.7344199 2.301931635 3.815211142 16.52845018 0.099999998 1.000000007 -0.353918379 LLRELAEDCKRPLPCMT(ph)YQPK ddPTM_HeLa_Curcumin_4h_R1 1 LLRELAEDCKRPLPCMTYQPK 21 3 A0A286YEQ6;A0A286YFD1;A0A286YFJ1;A0AVI2;A0A286YFD8 A0A286YEQ6 FER1L5 Fer-1-like protein 5 1 0 LLRELAEDCKRPLPCMT(0.525)Y(0.475)QPK 44.816 0.016985 14783000 1629.8 1405.4 1520.9 1479.3 1790 2316.7 2055.3 1188.7 1732.8 1812.7 TRUE FALSE FALSE 1500.79961 1526.876514 1577.265892 1473.179049 1768.655419 1836.190305 2112.966186 1551.129158 1542.716175 1875.69119 0.800131503 0.814034059 0.840898491 0.785405965 0.942935292 0.978940625 1.126500032 0.826964037 0.822478766 1 10.87320661 -5.528473866 24.75376645 0.882133125 0.987132519 0.256410591 0.09220292 176.3633324 780260.9598 0.015551537 0.031182576 2.96E-06 5.528473866 0.104999394 LLS(ph)DPELSATESPLADK ddPTM_HeLa_Curcumin_4h_R1 2 LLSDPELSATESPLADK 17 0 Q9H694;Q9H694-2;A6NGY7 Q9H694 BICC1 Protein bicaudal C homolog 1 1 0 LLS(0.994)DPELS(0.005)AT(0.001)ESPLADK;LLS(0.999)DPELS(0.001)ATESPLADK ; 120.32 0.00063114 6833600 7277.8 6158.7 6739.9 7309.9 6814.8 6159.8 3203 2859.8 7380 6222.4 TRUE FALSE FALSE 6701.754451 6691.030585 6989.686623 7279.653571 6733.537961 4882.188045 3292.86756 3731.739855 6570.432464 6438.627937 1.040866861 1.03920131 1.085586353 1.130621872 1.045803241 0.758265285 0.511423799 0.579586193 1.020470903 1 12.65253757 -5.053783225 2.819675597 1.036616294 0.546984041 0.959889396 0.042099932 0.041432178 0.64557401 0.007099481 0.022872894 8.84E-06 5.053783225 -0.489632254 LLS(ph)DSLPPSTGTFQEAQSR ddPTM_HeLa_Curcumin_4h_R1 4 LLSDSLPPSTGTFQEAQSR 19 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 0 LLS(0.82)DS(0.18)LPPSTGTFQEAQSR;LLS(0.988)DS(0.012)LPPSTGTFQEAQSR;LLS(0.991)DS(0.009)LPPSTGTFQEAQSR;LLS(0.767)DS(0.233)LPPSTGTFQEAQSR ;;; 276.14 1.38E-68 71961300 7190.88 5724.86 6233.39 6520.91 6876.91 8164.32 7215.83 7760.63 7484.59 6489.17 TRUE FALSE FALSE 6621.71426 6219.691389 6464.404917 6493.928202 6794.90734 6470.948001 7418.286769 10126.81036 6663.549203 6714.668174 0.986156589 0.926284252 0.962728872 0.967125707 1.011949833 0.963703318 1.10478829 1.508162444 0.99238697 1 12.71310039 -4.26308927 2.43837662 0.984137963 1.627436383 0.976631892 0.024691871 0.058838386 0.424573774 0.003728044 0.078829504 5.46E-05 4.26308927 0.643298421 LLS(ph)FSPEEFPTLK ddPTM_HeLa_Curcumin_4h_R1 1 LLSFSPEEFPTLK 13 0 Q5JSZ5;Q5JSZ5-5;A0A1W2PQP5 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 LLS(0.5)FS(0.5)PEEFPTLK 231.69 1.35E-19 99948000 2748.4 1647.6 1886.2 2177.1 2096.8 2793.9 1955.2 1751.8 2517.1 2282.3 TRUE FALSE FALSE 2530.86124 1790.011202 1956.104231 2168.091737 2071.797029 2214.413646 2010.05765 2285.915756 2240.980427 2361.609755 1.071667846 0.757962317 0.828292747 0.918056733 0.877281704 0.937671282 0.851138782 0.967948134 0.948920719 1 11.20555487 -7.281815647 24.99931574 1.033843153 0.877980623 0.450137629 0.063753725 401.1429181 492154.6523 0.010246677 0.011725025 5.23E-08 7.281815647 -0.15586253 LLS(ph)GSESSSK ddPTM_HeLa_Curcumin_4h_R1 1 LLSGSESSSK 10 0 G3XAI9;Q5BKY9-2;Q5BKY9 G3XAI9 FAM133B Protein FAM133B 1 0 LLS(0.964)GS(0.026)ES(0.004)S(0.004)S(0.004)K 108.56 0.008225 12914000 4337.7 3774.2 4131.6 3695.9 3495.6 3978.7 2518 2522.6 4135.8 4104.8 TRUE FALSE FALSE 3994.366468 4100.42503 4284.720731 3680.607345 3453.917253 3153.472771 2588.648303 3291.729127 3682.113087 4247.441494 0.940417066 0.965387054 1.008776869 0.86654692 0.813175945 0.742440543 0.609460614 0.774991046 0.866901426 1 12.05237836 -5.670871808 1.388011197 0.973418346 0.691771112 0.77753634 0.056872451 0.101529403 0.38832347 0.007109606 0.019467172 2.13E-06 5.670871808 -0.281647234 LLS(ph)PLSSAR ddPTM_HeLa_Curcumin_4h_R1 4 LLSPLSSAR 9 0 A0A087WZ13;E9PAU2;Q8IY67-2 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 0 LLS(0.957)PLS(0.04)S(0.003)AR;LLS(0.994)PLS(0.003)S(0.003)AR;LLS(0.998)PLS(0.002)SAR;LLS(0.871)PLS(0.003)S(0.126)AR ;;; 156.16 2.72E-05 182955400 20275 15321.1 17799.1 16548.5 18614.6 26771.6 22209.5 12822.5 17091.7 15379.2 TRUE FALSE FALSE 18670.21236 16645.38761 18458.7503 16480.02669 18392.63305 21218.86838 22832.6388 16732.02122 15216.78327 15913.62606 1.173221759 1.045983333 1.159933647 1.03559218 1.15577889 1.33337734 1.43478543 1.051427322 0.956210936 1 13.95797498 -1.000000046 0.023813293 9.33E-12 2.735302544 0.353110307 0.11563917 1695.345996 3.138091285 126.8333694 254.5490305 0.09999999 1.000000046 2.735302544 LLS(ph)PQMSGEEEDSDLAAK ddPTM_HeLa_Curcumin_4h_R1 1 LLSPQMSGEEEDSDLAAK 18 0 P42858;A0A3B3IU44 P42858 HTT Huntingtin 1 0 LLS(0.997)PQMS(0.002)GEEEDS(0.002)DLAAK 85.176 0.0045726 4798500 1309.9 1339.8 1380.3 1123.8 1506.4 1757.3 1562.3 1037.9 1551.4 1553.3 TRUE FALSE FALSE 1206.220033 1455.606342 1431.455132 1119.150013 1488.437164 1392.816171 1606.133933 1354.350932 1381.215301 1607.277059 0.750474242 0.905634989 0.890608824 0.696301865 0.92606135 0.866568812 0.999288781 0.842636883 0.859351095 1 10.65040292 -3.93018319 14.34162755 0.878855296 0.47956794 0.012495776 0.09088608 2144991.056 10439470.44 0.01509503 25109392.77 0.00011744 3.93018319 -0.399287356 LLS(ph)PQQPALQR ddPTM_HeLa_Curcumin_4h_R1 2 LLSPQQPALQR 11 0 Q14814-4;Q14814;Q14814-6;Q14814-3;Q14814-5;Q14814-2 Q14814-4 MEF2D Myocyte-specific enhancer factor 2D 1 0 LLS(1)PQQPALQR;LLS(1)PQQPALQR ; 105.25 0.0084649 55687000 5357.2 3379 4749.1 4904 4564.6 5386.7 3706.9 4333.2 4569.2 3582.9 TRUE FALSE FALSE 4933.171967 3671.065703 4925.105824 4883.708547 4510.170126 4269.437699 3810.905637 5654.372732 4067.970192 3707.405508 1.330626487 0.99019805 1.328450803 1.317284699 1.216530028 1.151597172 1.027917132 1.525156264 1.097255259 1 11.85619421 -9.490583842 1.149160532 0.995796365 1.234657152 0.189786657 0.150571469 0.545392336 1.251320182 0.106956929 0.024220338 3.23E-10 9.490583842 0.238860787 LLS(ph)PRPSLLTPTGDPR ddPTM_HeLa_Curcumin_4h_R1 1 LLSPRPSLLTPTGDPR 16 1 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 LLS(0.955)PRPS(0.042)LLT(0.003)PTGDPR 67.994 0.012186 180800000 5012.5 3736.7 4183.1 4694.4 4017.8 5160 4197.2 1672.8 5042.1 4209.1 TRUE FALSE FALSE 4615.755336 4059.683698 4338.129366 4674.975817 3969.890359 4089.757835 4314.962136 2182.829019 4488.994245 4355.365912 1.059785889 0.932110821 0.996042457 1.07338302 0.911494106 0.939015898 0.990723219 0.501181546 1.03068131 1 12.08857822 -4.258090171 4.967507069 1.008473044 0.474517574 0.886177278 0.052591247 0.042944717 3.217142397 0.007869299 0.078557645 5.52E-05 4.258090171 -0.533955471 LLS(ph)PYSPQTQETDSAVQK ddPTM_HeLa_Curcumin_4h_R1 1 LLSPYSPQTQETDSAVQK 18 0 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 1 0 LLS(0.848)PYS(0.152)PQTQETDSAVQK 271.45 4.18E-54 5288400 2753.3 2374.9 2471.9 2693.7 3103.8 4143.2 3521.9 1817.6 2954 2434.3 TRUE FALSE FALSE 2535.3734 2580.175774 2563.510789 2682.554183 3066.789212 3283.853617 3620.715035 2371.777873 2629.953591 2518.891744 1.006543217 1.024329759 1.01771376 1.064973987 1.21751529 1.303689857 1.437423837 0.941595795 1.044091552 1 11.2985734 -5.816713722 2.737397522 1.006679897 1.251175089 0.410534665 0.11630963 0.159634918 2.437668762 0.015798335 0.031854787 1.53E-06 5.816713722 0.244495192 LLS(ph)QESR ddPTM_HeLa_Curcumin_4h_R1 1 LLSQESR 7 0 D6RBD3;Q3KP44-2;Q3KP44 D6RBD3 ANKRD55 Ankyrin repeat domain-containing protein 55 1 0 LLS(1)QESR 71.296 0.0089448 0 368.87 220.39 300.61 319.62 261.24 365.6 249.02 368.46 367.8 254.75 TRUE FALSE FALSE 339.6735503 239.4395296 311.750871 318.2974971 258.1248836 289.7704388 256.006831 480.8017578 327.4532602 263.6025435 1.288582218 0.908335429 1.182655019 1.207490235 0.979220004 1.099270269 0.97118498 1.823964789 1.242223447 1 8.042220481 -4.25456974 24.95850111 1.11026531 1.823965126 0.755149844 0.123884657 322.4563704 1171504.682 0.018541671 0.244682166 5.56E-05 4.25456974 0.713699816 LLS(ph)S(ph)QY(ph)VERHFSR ddPTM_HeLa_Curcumin_4h_R1 1 LLSSQYVERHFSR 13 1 K7EKA8 K7EKA8 ADAM11 3 0 LLS(1)S(1)QY(1)VERHFSR 70.68 0.014616 10467000 3948.6 3192.2 3428.2 3623.3 3205.6 4142.3 3727.3 3097.1 3783.6 3675.5 TRUE FALSE FALSE 3636.064143 3468.119544 3555.252108 3608.307745 3167.375314 3283.140287 3831.878006 4041.391533 3368.548546 3803.223351 0.956048017 0.911889527 0.934799716 0.948749892 0.832813385 0.863252032 1.007534308 1.062622717 0.885708841 1 11.89300695 -8.246672294 0.896858645 0.993661408 0.934121567 0 0.070597536 0.803867676 1.368151198 0.022024624 0.014356016 5.67E-09 8.246672294 -0.059539841 (ac)ADLSLADALTEPS(ph)PDIEGEIKR ddPTM_HeLa_Curcumin_4h_R1 1 ADLSLADALTEPSPDIEGEIKR 22 1 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;H7C456;A0A0J9YW37;A0A0J9YVV8;P27816-7 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 ADLS(0.111)LADALT(0.191)EPS(0.698)PDIEGEIKR 57.316 0.00037549 23418000 1258.6 1448.7 1273.3 1400.4 1469.9 1970.1 1783.1 5127.3 1799.2 1534 TRUE FALSE FALSE 1158.980482 1573.919173 1320.489618 1394.605516 1452.372403 1561.479052 1833.128987 6690.590167 1601.832261 1587.306386 0.730155496 0.991566081 0.831905945 0.878598819 0.914991848 0.983728829 1.154867771 4.215059063 1.009151274 1 10.63236491 -4.255867251 3.871959242 0.888507547 4.556980058 0.992121027 0.08764531 0.018755849 0.551062723 0.015396697 0.195535394 5.55E-05 4.255867251 3.668472512 up TLENS(ph)PISSCDTSDTEGPVPVNSAAVLKK ddPTM_HeLa_Curcumin_4h_R1 1 TLENSPISSCDTSDTEGPVPVNSAAVLKK 29 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 0 T(0.003)LENS(0.47)PIS(0.258)S(0.087)CDT(0.139)S(0.035)DT(0.009)EGPVPVNSAAVLKK 148.56 1.44E-12 19277000 1512 1126.1 951.47 1185.5 1355.5 1724.1 1420.3 3459.9 1520.7 1020.3 TRUE FALSE FALSE 1392.323605 1223.435066 986.7323152 1180.594715 1339.336548 1366.502225 1460.149795 4514.807583 1353.883015 1055.755349 1.318793796 1.158824407 0.934622132 1.118246492 1.268605031 1.294336066 1.383038027 4.276376707 1.282383287 1 10.04405984 -4.25567973 3.979109503 1.156313651 4.578156744 0.982811941 0.122493134 0.025960113 0.838483851 0.020807735 0.257400367 5.55E-05 4.25567973 3.421843093 up LLS(ph)WSDNWR ddPTM_HeLa_Curcumin_4h_R1 1 LLSWSDNWR 9 0 J3KSY6;J3KSX6;Q8TCD5 J3KSY6 NT5C "5(3)-deoxyribonucleotidase, cytosolic type" 1 0 LLS(1)WSDNWR 133.42 0.0033814 14300000 2009.3 2015.4 2062.7 2232.2 2027.4 2390.9 1735.6 1627.5 2610.9 3061.5 TRUE FALSE FALSE 1850.261785 2189.602196 2139.145477 2222.963748 2003.224579 1895.000389 1784.296265 2123.717258 2324.490802 3167.886897 0.584068133 0.691186986 0.675259422 0.701718155 0.632353567 0.598190671 0.56324494 0.67038923 0.73376698 1 11.62930511 -9.33956474 0.767488221 1.033789372 0.634506104 0.373929106 0.092798191 0.20218117 0.183910104 0.052070424 0.009925241 4.58E-10 9.33956474 -0.399283268 LLSDS(ph)LPPSTGTFQEAQSR ddPTM_HeLa_Curcumin_4h_R1 1 LLSDSLPPSTGTFQEAQSR 19 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 0 LLS(0.081)DS(0.919)LPPSTGTFQEAQSR 159.54 2.20E-05 7385300 2211.8 2058.1 1828 1841.8 2069.4 2211.5 1943.6 1945.2 2131.9 1809 TRUE FALSE FALSE 2036.733696 2235.992993 1895.747288 1834.17912 2044.723757 1752.809971 1998.132185 2538.282525 1898.035904 1871.862615 1.088078623 1.194528367 1.012759843 0.97986845 1.092347131 0.936398834 1.067456644 1.35601967 1.013982484 1 10.87025884 -4.267391972 4.989528342 1.043581995 1.370277616 0.656327135 0.068180781 0.077086992 5.911633929 0.009602015 0.086039142 5.40E-05 4.267391972 0.326695621 LLSFS(ph)PEEFPTLK ddPTM_HeLa_Curcumin_4h_R1 1 LLSFSPEEFPTLK 13 0 Q5JSZ5;Q5JSZ5-5;A0A1W2PQP5 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 LLS(0.001)FS(0.999)PEEFPTLK 135.02 0.0013165 91678000 3133.5 2768.7 2341.6 2926.4 2978.1 3758.4 3280 2028 3471.4 3187 TRUE FALSE FALSE 2885.480169 3008.014091 2428.381756 2914.291332 2942.588103 2978.865474 3372.027972 2646.327864 3090.596105 3297.748013 0.874985037 0.912141886 0.736375777 0.883721655 0.89230229 0.90330294 1.02252445 0.802465153 0.937183828 1 11.68726545 -9.123099673 0.844968546 1.001323013 0.88109746 0.180157108 0.072247252 0.64465825 0.81898117 0.048689429 0.013616241 7.53E-10 9.123099673 -0.120225554 LLSGPSQES(ph)PQTLGK ddPTM_HeLa_Curcumin_4h_R1 1 LLSGPSQESPQTLGK 15 0 C9JZE3;C9JYJ8;Q9BWE0;Q9BWE0-4;E7EVL6 C9JZE3 REPIN1 Replication initiator 1 1 0 LLSGPS(0.002)QES(0.969)PQT(0.03)LGK 197.17 9.23E-07 13378000 1477.7 1246.7 1132.5 1601.5 1355.5 1799 1798.2 583.26 1604.5 1077.8 TRUE FALSE FALSE 1360.738486 1354.459193 1174.471446 1594.873417 1339.336548 1425.867121 1848.652652 761.093289 1428.490364 1115.25347 1.220115895 1.214485522 1.053098222 1.430054656 1.200925695 1.278513952 1.657607622 0.682439741 1.280866102 1 10.12315592 -9.217256041 0.444207735 0.939028902 1.250665548 0 0.252403281 2.966615007 0.79863579 0.422534344 0.067142401 6.06E-10 9.217256041 0.311636645 LLSISGK ddPTM_HeLa_Curcumin_4h_R1 1 LLSISGK 7 0 P06748;P06748-3;P06748-2;E5RI98 P06748 NPM1 Nucleophosmin 0 0 120.49 0.0094841 11923000 7534.4 6281.5 8216.7 5981.6 9119.2 8310.8 7787.3 6687.9 6011.8 5474.5 FALSE FALSE TRUE 6938.04429 6824.44487 8521.21813 5956.849724 9010.459496 6587.046398 8005.79068 8727.009923 5352.320581 5664.738468 1.224777513 1.204723732 1.50425623 1.051566592 1.590622329 1.162815624 1.413267484 1.54058479 0.944848665 1 12.46779364 -11.02081011 0.066432901 8.36E-11 1.932644092 0.512156124 0.155421685 82.68337176 0.750714688 18.41786046 6.17971529 9.53E-12 11.02081011 1.932644092 SAPGGGSK(ac)VPQK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 SAPGGGSKVPQKK 13 2 P06748;P06748-3;P06748-2;E5RI98 P06748 NPM1 Nucleophosmin 0 2 ; SAPGGGSK(1)VPQK(1)K;SAPGGGSK(1)VPQK(1)K 174.05 5.05E-08 7861800 4611.5 4477.4 4219.2 3944.6 4420 6509.9 6899.5 9738.2 5017.6 4032.4 FALSE TRUE FALSE 4246.494909 4864.406505 4375.567264 3928.27829 4367.294387 5159.673358 7093.081401 12707.33235 4467.181833 4172.5256 1.017727706 1.165818253 1.048661574 0.941462957 1.046678872 1.236582793 1.699949163 3.045477385 1.070618197 1 12.02670519 -4.081203611 1.325965795 1.019229077 4.63735235 0.989859255 0.06124931 0.127903632 0.142838504 0.009090313 0.695016488 8.29E-05 4.081203611 3.618123273 up AATEALGEKS(ph)PDSATVSGYDIMK ddPTM_HeLa_Curcumin_4h_R1 1 AATEALGEKSPDSATVSGYDIMK 23 1 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;H0Y7E2;K7EL39;J3QRL2;H7C3G6 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 AAT(0.001)EALGEKS(0.923)PDS(0.026)AT(0.011)VS(0.015)GY(0.023)DIMK 62.325 0.0025101 101840000 1531.5 1163.9 1378.2 1399.9 1546.6 1807.1 1572.1 2956.3 1596.1 1319.1 TRUE FALSE FALSE 1410.280159 1264.50233 1429.277304 1394.107585 1528.157805 1432.28709 1616.208895 3857.662261 1421.011823 1364.938627 1.033218733 0.926416987 1.047136682 1.021370161 1.119579866 1.049341752 1.18408906 2.826253273 1.041081112 1 10.41462037 -4.255643843 3.727086446 1.023089687 3.028436226 0.992654957 0.046082031 0.016344844 0.421460117 0.006844667 0.090742047 5.55E-05 4.255643843 2.005346538 up LLSSES(ph)EDEEEFIPLAQR ddPTM_HeLa_Curcumin_4h_R1 2 LLSSESEDEEEFIPLAQR 18 0 Q96AY2;Q96AY2-2;D6RIT8;F8W714 Q96AY2 EME1 Crossover junction endonuclease EME1 1 0 LLSSES(1)EDEEEFIPLAQR;LLS(0.015)S(0.076)ES(0.909)EDEEEFIPLAQR ; 253.79 6.31E-42 6840900 2016.94 1831.45 1518.44 1848.37 1852.63 2336.66 1687.09 1703.67 2063.38 1786.15 TRUE FALSE FALSE 1857.297071 1989.752377 1574.714722 1840.721935 1830.538597 1852.010376 1734.425205 2223.11114 1837.032376 1848.21858 1.004912022 1.076578495 0.85201758 0.995943854 0.990434041 1.002051595 0.938430781 1.202839948 0.993947576 1 10.85191967 -4.252206653 24.95741736 0.992863517 1.20284006 0.585000371 0.054868739 640.0532008 1730121.894 0.007013266 0.116604775 5.59E-05 4.252206653 0.209976543 RNSS(ph)SPVS(ph)PASVPGQR ddPTM_HeLa_Curcumin_4h_R1 1 RNSSSPVSPASVPGQR 16 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 2 0 RNS(0.331)S(0.434)S(0.237)PVS(0.6)PAS(0.397)VPGQR 96.096 0.0060189 16300000 5468.5 4203.5 4730.8 4520 4315.1 5562.5 3001.4 889.77 5461.8 4864.6 TRUE FALSE FALSE 5035.662455 4566.83181 4906.12761 4501.297438 4263.645251 4408.774798 3085.611206 1161.056777 4862.654205 5033.644488 1.000400896 0.907261492 0.974667087 0.894242223 0.847029476 0.875861378 0.612997444 0.230659273 0.966030521 1 12.29738761 -4.366578329 1.081879986 0.980945913 2.16E-28 0.951394428 0.050087691 0.224985321 0.234872009 0.00821938 0.240712783 4.30E-05 4.366578329 -0.980945913 down LLSTDPVTAK ddPTM_HeLa_Curcumin_4h_R1 1 LLSTDPVTAK 10 0 P63010-2;A0A087WYD1;A0A087X253;A0A087WU93;P63010;A0A087WZQ6;P63010-3 P63010-2 AP2B1 AP-2 complex subunit beta 0 0 105.4 0.0067474 800590 580.77 496.67 350.99 446.59 592.27 509.81 393.48 359.57 615.27 441.18 FALSE FALSE TRUE 534.8014417 539.5999417 363.9979982 444.7421289 585.2075671 404.0696593 404.5199898 469.2012377 547.7764203 456.5109722 1.171497454 1.182008702 0.797347754 0.974220021 1.281913476 0.885125843 0.886112305 1.02779838 1.199919506 1 8.834505725 -6.804330512 24.99999892 1.090824455 0.981131717 0.232659897 0.134049002 222.2410927 129537.0947 0.022396314 0.029434639 1.57E-07 6.804330512 -0.109692738 LLT(ph)PTHSFLAR ddPTM_HeLa_Curcumin_4h_R1 1 LLTPTHSFLAR 11 0 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-3 MAP7 Ensconsin 1 0 LLT(0.985)PT(0.015)HSFLAR 96.371 0.012641 38506000 2908.4 2401 2840.6 2200 2630.5 6144 4877.3 2325.3 2782.2 1945 TRUE FALSE FALSE 2678.197071 2608.531741 2945.875135 2190.896983 2599.133006 4869.665143 5014.143911 3034.273266 2476.999621 2012.588605 1.330722565 1.296107776 1.463724443 1.088596535 1.291437802 2.419602859 2.491390391 1.507647046 1.230753078 1 10.97483658 -5.316307364 6.565787701 1.194676957 2.173551466 0.686192317 0.276366826 0.087495221 8.488669773 0.039677716 0.08998517 4.83E-06 5.316307364 0.978874509 LLTTIGK ddPTM_HeLa_Curcumin_4h_R1 1 LLTTIGK 7 0 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6;C9JF13;A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-4 Q04637-9;A0A0A0MSA7 EIF4G1;EIF4G3 Eukaryotic translation initiation factor 4 gamma 1;Eukaryotic translation initiation factor 4 gamma 3 0 0 107.32 0.015659 1157600 2716 1862.2 2125 2323 2243.7 2986.1 2085.5 1859.8 1875.5 2162.8 FALSE FALSE TRUE 2501.025734 2023.16027 2203.754369 2313.388042 2216.945343 2366.7492 2144.013517 2426.844459 1669.762342 2237.957139 1.11754854 0.904021009 0.984716968 1.033705249 0.990611171 1.05754894 0.9580226 1.08440167 0.746110063 1 11.12796669 -7.290684581 24.94689145 1.055509025 1.00244949 0 0.112028307 1008.324106 860123.107 0.010500758 0.012009531 5.12E-08 7.290684581 -0.053059536 LLVDVDESTLS(ph)PEEQKER ddPTM_HeLa_Curcumin_4h_R1 3 LLVDVDESTLSPEEQKER 18 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 LLVDVDES(0.001)T(0.007)LS(0.992)PEEQKER;LLVDVDES(0.001)T(0.004)LS(0.995)PEEQKER;LLVDVDES(0.046)T(0.364)LS(0.59)PEEQKER ;; 99.873 0.00061455 44890900 6499.9 5812.8 5317.1 6711.5 6502.6 6969.1 5238 5196.4 6242.9 5899.8 TRUE FALSE FALSE 5985.426056 6315.232531 5514.156403 6683.729591 6425.060742 5523.630102 5384.964183 6780.758439 5558.069489 6104.817611 0.98044306 1.034467028 0.903246707 1.09482871 1.052457445 0.904798547 0.882084368 1.110722526 0.910439892 1 12.57573248 -5.260592321 24.99995098 0.998759945 0.957490073 0.026939131 0.079114149 177.0585701 5225586.48 0.0097967 0.023458506 5.49E-06 5.260592321 -0.041269872 LLVGVDEK ddPTM_HeLa_Curcumin_4h_R1 2 LLVGVDEK 8 0 P53396;P53396-2 P53396 ACLY ATP-citrate synthase 0 0 ; ; 107.66 0.0077991 9461300 12646 10135.3 10590.3 10659.1 10511.3 11874.7 10106.3 9740.2 11280 9557.6 FALSE FALSE TRUE 11645.05576 11011.35017 10982.78583 10614.99547 10385.95961 9411.753365 10389.85558 12709.94214 10042.61222 9889.725889 1.177490245 1.113413081 1.110524797 1.07333566 1.050176691 0.951669791 1.050570632 1.285166271 1.015459107 1 13.27171482 -6.042530182 21.04180433 1.090519828 1.071156395 0 0.091245439 511.6856688 253155.2878 0.015239822 0.025277002 9.07E-07 6.042530182 -0.019363433 LLVRPTSSET(ph)PSAAELVSAIEELVK ddPTM_HeLa_Curcumin_4h_R1 1 LLVRPTSSETPSAAELVSAIEELVK 25 1 E7EPJ7;O75962-5;O75962-4;O75962;E7EWP2;O75962-2;A0A1W2PRD7 E7EPJ7 TRIO Triple functional domain protein 1 0 LLVRPT(0.21)S(0.21)S(0.21)ET(0.319)PS(0.049)AAELVSAIEELVK 103.4 3.43E-07 12459000 2384.6 2000.3 2183.5 2549.2 1886 2762.5 2049.7 1887.2 2701.3 2452.9 TRUE FALSE FALSE 2195.856394 2173.197019 2264.422431 2538.652086 1863.510682 2189.52636 2107.209066 2462.598592 2404.974148 2538.138092 0.865144572 0.856217014 0.892158877 1.000202508 0.734203819 0.862650605 0.830218447 0.970238223 0.947534792 1 11.30955485 -9.260809737 0.689763048 1.013483537 0.871865826 0.215799967 0.070848485 0.861419411 0.628775827 0.072849335 0.01408249 5.49E-10 9.260809737 -0.141617711 LLVVTDPR ddPTM_HeLa_Curcumin_4h_R1 1 LLVVTDPR 8 0 C9J9K3;A0A0C4DG17;P08865 C9J9K3 RPSA 40S ribosomal protein SA 0 0 100.74 0.012739 4199400 7103.3 4386.2 6312.9 4795 5691 7148.7 6062.5 6008.8 5947.5 5382.4 FALSE FALSE TRUE 6541.06631 4765.323583 6546.861627 4775.159561 5623.138542 5665.979038 6232.597434 7840.855459 5295.07413 5569.437999 1.174457155 0.855620187 1.175497712 0.85738625 1.009642004 1.017334072 1.119071158 1.407836026 0.950737602 1 12.44331604 -4.277351618 2.994603115 1.049891252 1.459810613 0.521477123 0.110145835 0.240574363 3.198798232 0.015466218 0.23026794 5.28E-05 4.277351618 0.409919361 LLYLT(ph)T(ph)T(ph)NESGVFITGHRGQPYTYDAK ddPTM_HeLa_Curcumin_4h_R1 1 LLYLTTTNESGVFITGHRGQPYTYDAK 27 1 B1AQ74;Q6NSI4-3;Q6NSI4-2;Q6NSI4-4;Q6NSI4 B1AQ74 CXorf57 Uncharacterized protein CXorf57 3 0 LLY(0.307)LT(0.717)T(0.717)T(0.717)NES(0.401)GVFIT(0.106)GHRGQPY(0.012)T(0.012)Y(0.012)DAK 42.863 0.0083963 0 583.74 336.87 542.56 546.12 396.67 537.5 612.58 624 567.71 632.53 TRUE FALSE FALSE 537.536363 365.9875417 562.6677509 543.8603001 391.9399693 426.0164411 629.7673461 814.2547275 505.4336333 654.5103704 0.821280131 0.559177606 0.859677365 0.83094222 0.598829273 0.65089334 0.962196131 1.244066961 0.772231665 1 9.354272241 -8.832349833 0.990290401 0.987010496 0.805423892 0 0.19847463 0.802168271 1.553141573 0.084994009 0.03725149 1.47E-09 8.832349833 -0.181586604 LLYNNVSNFGR ddPTM_HeLa_Curcumin_4h_R1 1 LLYNNVSNFGR 11 0 A0A087WVQ6;Q00610-2;Q00610;J3KS13 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 122.94 0.0017192 1614000 315.87 266.81 200.95 206.19 269.93 410.49 247.1 159.44 167.72 281.02 FALSE FALSE TRUE 290.8685562 289.8718675 208.3973838 205.3368404 266.711261 325.3497468 254.032961 208.052522 149.3215356 290.7854241 1.000285888 0.996858314 0.716670667 0.706145575 0.91720987 1.11886539 0.873609679 0.7154847 0.513511075 1 8.183811144 -6.877040998 13.5762993 1.000047692 0.852732167 0 0.192607357 0.599705141 68.45096663 0.019736839 0.025941261 1.33E-07 6.877040998 -0.147315525 LMANS(ph)PSHLCEIGSLK ddPTM_HeLa_Curcumin_4h_R1 1 LMANSPSHLCEIGSLK 16 0 Q9Y6X0 Q9Y6X0 SETBP1 SET-binding protein 1 0 LMANS(0.989)PS(0.011)HLCEIGSLK 75.229 0.018025 2804000 856.6 634.42 969.86 873.41 848.75 1103.4 650.11 737.8 994.24 798.4 TRUE FALSE FALSE 788.7992061 689.2564379 1005.803865 869.7960608 838.6292106 874.5424021 668.3503369 962.7518236 885.1743595 826.1443406 0.954795872 0.834305101 1.217467476 1.052837886 1.015112214 1.058583058 0.808999474 1.165355467 1.071452428 1 9.690250055 LMAVNVT(ph)Y(ph)SSTGQIASIQR ddPTM_HeLa_Curcumin_4h_R1 1 LMAVNVTYSSTGQIASIQR 19 0 Q9P273 Q9P273 TENM3 Teneurin-3 2 0 LMAVNVT(0.978)Y(0.771)S(0.121)S(0.122)T(0.008)GQIAS(0.001)IQR 44.539 0.0095996 0 4075.1 3487.3 3356.2 4127.1 4269.2 2333.6 3048.8 2775.7 4138.4 3845.2 TRUE FALSE FALSE 3752.551535 3788.726673 3480.583724 4110.023154 4218.292578 1849.585055 3134.341123 3621.998152 3684.427874 3978.820414 0.943131668 0.952223594 0.874777789 1.032975286 1.060186724 0.464857637 0.787756369 0.910319586 0.926010096 1 11.95812507 -5.292677855 24.99517174 0.973016097 0.727655544 0.497645991 0.114520205 379.3427796 303526.9462 0.015501126 0.034664751 5.10E-06 5.292677855 -0.245360553 LMELHGEGSS(ph)SGK ddPTM_HeLa_Curcumin_4h_R1 1 LMELHGEGSSSGK 13 0 P61247;H0Y9Y4;D6RAT0;D6R9B6;D6RG13 P61247 RPS3A 40S ribosomal protein S3a 1 0 LMELHGEGS(0.087)S(0.72)S(0.193)GK 90.725 0.007152 10833000 3846.1 3649.6 3865.7 3311.4 4380 4988.1 3969.6 3878.2 4088.4 3723.4 TRUE FALSE FALSE 3541.677127 3965.055162 4008.966243 3297.698304 4327.771361 3953.511833 4080.976292 5060.645327 3639.912749 3852.787873 0.919250487 1.029139234 1.040536457 0.855925219 1.123283062 1.026143137 1.059226832 1.313502195 0.944747769 1 11.91168704 -1.000000048 0.697673222 0.969742822 41.86536066 0.669338287 0.068227404 112.1708932 0.560770131 0.011034354 7163.407449 0.099999989 1.000000048 40.89561784 SLPTPAVLLS(ph)PTKEPPPLLAKPK ddPTM_HeLa_Curcumin_4h_R1 1 SLPTPAVLLSPTKEPPPLLAKPK 23 2 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 0 SLPTPAVLLS(0.819)PT(0.181)KEPPPLLAKPK 68.411 0.00056309 903860000 4480.1 3129.3 3893.1 4366.6 3978 5265.1 4467.4 6963.6 4597.1 4119.4 TRUE FALSE FALSE 4125.495358 3399.782748 4037.381711 4348.532166 3930.564948 4173.05891 4592.743221 9086.769584 4092.809631 4262.548843 0.967847058 0.797593851 0.947175472 1.020171809 0.922116108 0.979005535 1.077464069 2.131769023 0.96017894 1 12.05750065 -4.255641213 3.650860941 0.967183338 2.268292569 0.972236138 0.059512415 0.033312652 0.801459686 0.008722464 0.118314866 5.55E-05 4.255641213 1.301109232 up LMGAGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 LMGAGKK 7 1 E9PM92;O00193 E9PM92 C11orf58;SMAP Small acidic protein 0 1 LMGAGK(1)K 77.748 0.020054 16567000 10933 10405 9439.4 8511.6 8946.5 10484 8550.1 8200.4 9535.2 9032.9 FALSE TRUE FALSE 10067.64151 11304.36184 9789.232468 8476.381254 8839.818831 8309.500221 8789.992795 10700.66421 8489.212416 9346.792603 1.077122596 1.209437538 1.04733601 0.906875932 0.9457596 0.889021569 0.940428783 1.144848791 0.90824872 1 13.19025567 -6.337979975 8.518265583 1.053939868 0.958743408 0.155649417 0.095693887 0.42895589 44.57466646 0.013599952 0.020794315 4.59E-07 6.337979975 -0.09519646 LMGEDEK(ac)PAAK ddPTM_HeLa_Curcumin_4h_R1 1 LMGEDEKPAAK 11 1 Q9UHV9 Q9UHV9 PFDN2 Prefoldin subunit 2 0 1 LMGEDEK(1)PAAK 140.3 4.29E-05 1971700 526.92 734.45 550.58 713 1383.8 1600.8 1012 1257.8 1502.6 788.68 FALSE TRUE FALSE 485.213726 797.9325854 570.9849791 710.0497949 1367.299089 1268.776035 1040.393996 1641.29743 1337.768539 816.0865713 0.594561586 0.977754828 0.699662265 0.870066755 1.675433878 1.55470765 1.27485739 2.011180538 1.639248318 1 9.672578393 -5.783145268 7.644336386 0.812124834 1.598990247 0.457698123 0.330541708 0.062652723 15.8046599 0.032065367 0.059466885 1.65E-06 5.783145268 0.786865413 LMHNAS(ph)DS(ph)EVDQDDVVEWK ddPTM_HeLa_Curcumin_4h_R1 2 LMHNASDSEVDQDDVVEWK 19 0 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 2 0 LMHNAS(1)DS(1)EVDQDDVVEWK;LMHNAS(1)DS(1)EVDQDDVVEWK ; 88.222 0.0022892 16317700 5378.4 5020.4 5092.5 5005.3 5958.1 5791.8 5287.4 5303.2 5030.1 5127.8 TRUE FALSE FALSE 4952.693965 5454.341006 5281.23253 4984.589395 5887.053549 4590.515393 5435.750214 6920.121267 4478.310615 5305.990668 0.933415506 1.027959027 0.995333927 0.939426717 1.109510724 0.86515708 1.024455291 1.304209091 0.84401027 1 12.37340642 -4.280565332 3.987003384 0.975696299 1.328240786 0.650890828 0.073884309 0.080058605 2.605670924 0.007847135 0.078637084 5.24E-05 4.280565332 0.352544487 LMHNAS(ph)DSEVDQDDVVEWK ddPTM_HeLa_Curcumin_4h_R1 2 LMHNASDSEVDQDDVVEWK 19 0 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 0 LMHNAS(0.97)DS(0.03)EVDQDDVVEWK;LMHNAS(0.772)DS(0.228)EVDQDDVVEWK ; 126.55 8.63E-05 24417000 4735.7 4349.3 4077.4 3835.5 4660.4 5357.1 4178.9 2796.6 4419 3900.8 TRUE FALSE FALSE 4360.864348 4725.234112 4228.512031 3819.629717 4604.827774 4245.977073 4296.148687 3649.270466 3934.246756 4036.35251 1.080397299 1.170669336 1.04760722 0.946307268 1.140838855 1.051934157 1.064364095 0.904101031 0.97470346 1 11.97883646 -4.258191241 24.0710291 1.051161185 0.904100937 0.317465776 0.065440182 170.9772991 1266956.068 0.008769811 0.083037975 5.52E-05 4.258191241 -0.147060248 LMHNASDS(ph)EVDQDDVVEWK ddPTM_HeLa_Curcumin_4h_R1 1 LMHNASDSEVDQDDVVEWK 19 0 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 0 LMHNAS(0.183)DS(0.817)EVDQDDVVEWK 135.76 9.10E-05 7291300 3603.2 3026.5 3167.5 3013.3 3999 3714.2 2983.2 1969.9 3377.1 3104.7 TRUE FALSE FALSE 3318.002918 3288.097174 3284.890336 3000.831763 3951.314537 2943.833052 3066.900563 2570.513442 3006.640579 3212.588094 1.032813053 1.023504128 1.022505917 0.93408544 1.229947451 0.916343137 0.954651039 0.800137885 0.935893582 1 11.6495203 -4.325267616 1.564895249 1.022074231 0.741886488 0.383006138 0.08246225 0.636219632 1.584283427 0.010228681 0.261501 4.73E-05 4.325267616 -0.280187742 LMIEMDGTENK ddPTM_HeLa_Curcumin_4h_R1 4 LMIEMDGTENK 11 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879 P06733 ENO1 Alpha-enolase;Enolase 0 0 ;;; ;;; 163.38 4.73E-08 9116200 4648.51 4032.48 4039.82 4543.05 5595.47 7585.5 5688.5 6325.6 5546.3 4283.09 FALSE FALSE TRUE 4280.575528 4381.029603 4189.539283 4524.252063 5528.747675 6012.181794 5848.104 8254.246321 4937.884766 4431.927059 0.965849724 0.988515728 0.945308717 1.020831797 1.247481649 1.35656154 1.319539767 1.862450851 1.114162011 1 12.11371842 -1 0.47025689 0.973001933 23.58637524 0.898962953 0.085325482 14.39967851 0.14865007 0.015177281 318.930608 0.1 1 22.6133733 LMLS(ph)TSEYSQS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 LMLSTSEYSQSPK 13 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 LMLS(0.953)T(0.044)S(0.002)EYS(0.001)QS(1)PK 103.11 0.0066565 17434000 4626.7 3680.9 4312.4 4077 3768.3 3754.4 4010.8 2469.1 4192.8 4117.3 TRUE FALSE FALSE 4260.491813 3999.060594 4472.221338 4060.130454 3723.365484 2975.695119 4123.332253 3221.917224 3732.86033 4260.375869 1.000027215 0.938663798 1.049724596 0.952998181 0.873952346 0.698458355 0.967832975 0.756251871 0.876180986 1 12.056765 -5.749384583 3.015043916 0.997672257 0.819481938 0.441872037 0.079258998 0.120858743 2.260496773 0.009151349 0.01875664 1.78E-06 5.749384583 -0.178190319 LMLSTSEYSQS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 LMLSTSEYSQSPK 13 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 LMLSTSEYSQS(1)PK;LMLSTSEYS(0.011)QS(0.989)PK;LMLST(0.002)SEYS(0.002)QS(0.996)PK;LMLSTSEYS(0.008)QS(0.992)PK ;;; 188.4 1.10E-05 223845700 12239.1 9314 9988.8 10577.3 9686.3 10496.1 9724.4 8059.2 11386.8 8481.5 TRUE FALSE FALSE 11270.36232 10119.06066 10358.99372 10533.53394 9570.797199 8319.090545 9997.240492 10516.41298 10137.69653 8776.231494 1.284191549 1.153007491 1.180346453 1.200234285 1.090536092 0.947911476 1.139126799 1.198283453 1.155130939 1 13.09938587 -4.278901226 6.154014786 1.130266961 1.199458141 0.050220524 0.091694874 0.44455746 75.94075879 0.01663834 0.116421493 5.26E-05 4.278901226 0.069191181 LMQNST(ph)SPPLK ddPTM_HeLa_Curcumin_4h_R1 1 LMQNSTSPPLK 11 0 Q9Y2Q0-3;Q9Y2Q0-2;Q9Y2Q0 Q9Y2Q0-3 ATP8A1 Phospholipid-transporting ATPase IA 1 0 LMQNS(0.135)T(0.73)S(0.135)PPLK 138.4 0.0046034 4931200 2540 2007.8 1972.9 2146.6 2195.6 2032.4 1805.7 1989.4 2426.1 2258.6 TRUE FALSE FALSE 2338.95632 2181.345285 2046.01741 2137.717938 2169.418904 1610.85733 1856.363082 2595.958902 2159.9629 2337.086182 1.000800201 0.933361081 0.875456552 0.91469367 0.928257982 0.689258848 0.794306644 1.110767297 0.924211917 1 11.19049522 -7.011314732 1.941737527 1.001296695 0.873787998 0.110368498 0.103561099 0.344118077 2.562935109 0.01732016 0.022586329 9.74E-08 7.011314732 -0.127508696 LMS(ph)DVEDVSLENVHTR ddPTM_HeLa_Curcumin_4h_R1 1 LMSDVEDVSLENVHTR 16 0 Q9NSI6-3;Q9NSI6-2;Q9NSI6 Q9NSI6-3 BRWD1 Bromodomain and WD repeat-containing protein 1 1 0 LMS(1)DVEDVSLENVHTR 151.58 0.00016189 2597900 1420.4 1319.1 1501.2 1387.5 1532.6 1722.3 1238 1485.2 1876.8 1547.7 TRUE FALSE FALSE 1307.973841 1433.117126 1556.835793 1381.758893 1514.324746 1365.075566 1272.734948 1938.030643 1670.919736 1601.48246 0.816726923 0.894869074 0.972121663 0.862799892 0.945576854 0.852382464 0.794723002 1.210147905 1.043358124 1 10.64519228 -4.248529664 24.8732927 0.903270891 1.210148115 0.578875982 0.076864695 1126.802607 2170983.905 0.010855278 0.26916981 5.64E-05 4.248529664 0.306877224 LMSLLTSPHQPPPPPPASASPSAVPNGPQS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 LMSLLTSPHQPPPPPPASASPSAVPNGPQSPK 32 0 Q96RU3-5;Q96RU3-2;Q96RU3 Q96RU3-5 FNBP1 Formin-binding protein 1 1 0 LMSLLTSPHQPPPPPPAS(0.006)AS(0.006)PS(0.005)AVPNGPQS(0.983)PK 120.31 1.19E-13 20949000 1095.4 1494.3 1086.6 946.36 1577.9 2158.9 1197.2 655.84 1636.1 1005.2 TRUE FALSE FALSE 1008.697934 1623.460634 1126.870352 942.4442131 1559.084573 1711.119804 1230.79021 855.8025969 1456.623923 1040.130625 0.969780054 1.560823799 1.083393109 0.906082554 1.498931514 1.645100877 1.183303501 0.82278377 1.400424031 1 10.02254901 ANVVTT(ph)PSTNRK ddPTM_HeLa_Curcumin_4h_R1 1 ANVVTTPSTNRK 12 1 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;E9PDP5 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 0 ANVVT(0.003)T(0.994)PS(0.002)T(0.002)NRK 87.863 0.0089903 47511000 6920.7 6341.3 6113.6 6739.8 6413.6 6537.7 4533.3 638.79 6992.5 6036.1 TRUE FALSE FALSE 6372.919292 6889.413716 6340.175394 6711.912493 6337.122009 5181.707325 4660.492197 833.5541304 6225.440244 6245.854026 1.020343938 1.103037901 1.015101437 1.074618854 1.014612571 0.829623508 0.74617373 0.13345719 0.996731627 1 12.60868314 -4.366474655 1.548153509 1.019536633 7.51E-16 0.950866158 0.060611521 0.127258894 0.328095705 0.008306081 0.184211245 4.30E-05 4.366474655 -1.019536633 down TAPAAPAEDAVAAAAAAPSEPSEPSRPS(ph)PQPKPR ddPTM_HeLa_Curcumin_4h_R1 1 TAPAAPAEDAVAAAAAAPSEPSEPSRPSPQPKPR 34 2 Q53GA4 Q53GA4 PHLDA2 Pleckstrin homology-like domain family A member 2 1 0 TAPAAPAEDAVAAAAAAPS(0.006)EPS(0.014)EPS(0.272)RPS(0.707)PQPKPR 98.722 3.89E-11 18375000 3762.2 3190.6 3546.9 3341.2 4480.7 4504.6 2509.1 677.85 3904.6 3324.8 TRUE FALSE FALSE 3464.4179 3466.381247 3678.351234 3327.375 4427.270579 3570.295183 2579.498593 884.5233446 3476.275149 3440.336553 1.006999707 1.007570391 1.069183546 0.967165552 1.28687136 1.037774976 0.749780887 0.257103725 1.010446244 1 11.74833399 -4.366191739 2.342288594 1.027605386 0.163303902 0.884307299 0.087874331 0.109359079 0.831236767 0.012597849 0.173828753 4.30E-05 4.366191739 -0.864301484 down LNDPFQPFPGNDS(ph)PKEKDPEIFCDPFTSATTTTNK ddPTM_HeLa_Curcumin_4h_R1 1 LNDPFQPFPGNDSPKEKDPEIFCDPFTSATTTTNK 35 2 P42566;B1AUU8;P42566-2 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 0 LNDPFQPFPGNDS(0.994)PKEKDPEIFCDPFT(0.004)S(0.001)AT(0.001)TTTNK 61.776 0.00010893 23826000 1479 1497.3 1752 1505.5 1540.3 2140.1 1744.3 1465.5 1441.1 1341.4 TRUE FALSE FALSE 1361.935589 1626.71994 1816.930661 1499.27064 1521.932929 1696.219136 1793.240363 1912.324204 1283.014935 1388.01355 0.981212027 1.171976988 1.309015075 1.080155622 1.09648276 1.222047966 1.291947304 1.37774174 0.924353322 1 10.43880594 -1 0.188009281 0.946436007 2.859090673 0.669725989 0.083759671 24.92496782 0.27711995 0.103906537 13.88250672 0.1 1 1.912654665 LNDS(ph)PTLK ddPTM_HeLa_Curcumin_4h_R1 1 LNDSPTLK 8 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 0 LNDS(0.993)PT(0.007)LK 116.84 0.0092625 100040000 6344.3 5442 5596 5833.1 5761.7 7088.5 4701 2593.6 6228.9 6002.1 TRUE FALSE FALSE 5842.141961 5912.382231 5803.392683 5808.964178 5692.995491 5618.265196 4832.897408 3384.376701 5545.605254 6210.672528 0.940661729 0.951971337 0.934422586 0.93531967 0.916647185 0.904614624 0.778160076 0.544929182 0.892915418 1 12.60053379 -3.863340385 0.893218396 0.965053603 2.47E-17 0.940203697 0.030349796 0.54384496 0.199825564 0.00434101 0.60530719 0.000136981 3.863340385 -0.965053603 LNDSPT(ph)LK ddPTM_HeLa_Curcumin_4h_R1 1 LNDSPTLK 8 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 0 LNDS(0.226)PT(0.774)LK 127.51 0.017228 77603000 9927.5 9022.2 8343.1 9624.4 9329.3 9843.8 8442.9 4071.9 9676.1 8510.8 TRUE FALSE FALSE 9141.7279 9802.038766 8652.302625 9584.576783 9218.054191 7802.084918 8679.785051 5313.403565 8614.656038 8806.549667 1.038060108 1.113039628 0.982484963 1.088346418 1.0467271 0.88594117 0.985605644 0.603346801 0.978210124 1 13.10436118 -3.861787902 1.32211922 1.026113244 1.55E-16 0.808359969 0.059992519 0.9792807 0.725539294 0.008027699 1.746391182 0.000137471 3.861787902 -1.026113244 LNEAAAGLNQAATELVQAS(ph)RGTPQDLAR ddPTM_HeLa_Curcumin_4h_R1 2 LNEAAAGLNQAATELVQASRGTPQDLAR 28 1 Q9Y490 Q9Y490 TLN1 Talin-1 1 0 LNEAAAGLNQAAT(0.007)ELVQAS(0.902)RGT(0.091)PQDLAR;LNEAAAGLNQAAT(0.079)ELVQAS(0.913)RGT(0.008)PQDLAR ; 99.836 3.63E-08 54214000 2490.1 2074.7 1976.37 1891.28 1633.51 2232.2 1800.63 1954.44 3045.2 2238 TRUE FALSE FALSE 2293.005957 2254.027823 2049.616011 1883.454384 1614.03146 1769.216558 1851.150832 2550.339759 2711.149179 2315.770333 0.990169847 0.973338241 0.885068774 0.81331657 0.696973891 0.763986192 0.799367193 1.10129218 1.170733185 1 11.17727647 -6.653470694 2.462857765 0.994967632 0.822198043 0.390393288 0.113449918 0.216624836 2.679669471 0.015892565 0.023312093 2.22E-07 6.653470694 -0.172769589 LNELEAMT(ph)RVR ddPTM_HeLa_Curcumin_4h_R1 1 LNELEAMTRVR 11 1 P29375;P29375-2;F5H322;F5GZR8 P29375 KDM5A Lysine-specific demethylase 5A 1 0 LNELEAMT(1)RVR 73.499 0.020017 49457000 1630.2 1684.6 1655.3 1793.9 1995.4 2207.5 1512.2 1826.5 1784.9 1584.6 TRUE FALSE FALSE 1501.16795 1830.209318 1716.646874 1786.477317 1971.606158 1749.639616 1554.628262 2383.391442 1589.100936 1639.664732 0.915533475 1.11620948 1.046949929 1.089538173 1.202444695 1.067071568 0.948137892 1.453584623 0.969162113 1 10.67918514 -6.85598523 1.335396694 0.961196489 1.137510819 0.265890909 0.127180705 0.388233594 1.382332348 0.022115258 0.031463819 1.39E-07 6.85598523 0.176314331 LNEQAS(ph)EEILK ddPTM_HeLa_Curcumin_4h_R1 2 LNEQASEEILK 11 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;Q01105-2 Q01105;Q01105-2 SET Protein SET 1 0 LNEQAS(1)EEILK;LNEQAS(1)EEILK ; 160.46 0.00034257 16486200 4208.6 4187.4 4958.3 4075.9 5673.6 4971.6 4052.6 3601.9 3585.5 3370.8 TRUE FALSE FALSE 3875.484869 4549.340197 5142.05896 4059.035006 5605.946026 3940.434119 4166.305049 4700.102729 3192.17962 3487.935049 1.111111536 1.304307601 1.474241604 1.163735835 1.607239225 1.129732654 1.194490434 1.347531609 0.915206154 1 11.76815746 -7.397396638 2.43283405 1.043748266 1.317842178 0.495580692 0.142551717 0.186713407 2.093175497 0.02420085 0.027318779 4.01E-08 7.397396638 0.274093912 LNFDMTAS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 LNFDMTASPK 10 0 Q9ULU4-9;Q9ULU4-11;Q9ULU4-23;Q9ULU4-21;Q9ULU4;Q9ULU4-5;H7C4X9;A0A087WYS3;A0A087WVZ6;Q9ULU4-10;Q9ULU4-13;Q9ULU4-20;Q9ULU4-12;Q9ULU4-7;Q9ULU4-19;Q9ULU4-16;Q9ULU4-22;Q9ULU4-18;Q9ULU4-14;Q9ULU4-15;Q9ULU4-6;Q9ULU4-3;Q9ULU4-4;A0A087WV57;Q9ULU4-8;Q9ULU4-17 Q9ULU4-9 ZMYND8 Protein kinase C-binding protein 1 1 0 LNFDMT(0.001)AS(0.999)PK 116.24 0.0052181 30842000 1500.1 1207.1 1464.3 1469.7 1477.7 1855.2 1732.5 1207.5 1586.6 1531.9 TRUE FALSE FALSE 1381.365502 1311.436345 1518.568246 1463.618771 1460.079393 1470.410608 1781.109287 1575.661191 1412.553949 1585.133411 0.871450625 0.827334997 0.958006585 0.923341064 0.921108206 0.927625774 1.12363368 0.994024339 0.891126223 1 10.63038855 -4.780327537 24.7161307 0.928359839 1.058828982 0.51927571 0.054147829 134.1965234 175603.6749 0.008882619 0.026712729 1.66E-05 4.780327537 0.130469142 LNFSHGTHEYHAETIK ddPTM_HeLa_Curcumin_4h_R1 2 LNFSHGTHEYHAETIK 16 0 P14618;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 57.973 0.011941 58049900 3287.2 2865.8 2386.31 2464.4 4590.4 8821.2 4081.7 3171.1 4449 2481.5 FALSE FALSE TRUE 3027.014651 3113.506982 2474.748748 2454.202966 4535.662478 6991.583685 4196.221517 4137.953792 3960.955831 2567.73194 1.178867079 1.212551409 0.963787812 0.955786283 1.766408092 2.722863542 1.634213233 1.611520941 1.542589306 1 11.32627888 -5.662720515 4.916053282 1.079639349 1.995290978 0.578925624 0.330949888 0.091066332 3.648354723 0.042506651 0.086232786 2.17E-06 5.662720515 0.91565163 LNGDTEEGFNRLS(ph)DEFSK ddPTM_HeLa_Curcumin_4h_R1 1 LNGDTEEGFNRLSDEFSK 18 1 A0A087WVC1;Q9BQ39 A0A087WVC1 DDX50 ATP-dependent RNA helicase DDX50 1 0 LNGDT(0.003)EEGFNRLS(0.996)DEFS(0.001)K 58.024 0.014117 15968000 1414.4 1240 1213.2 1192.7 1549.5 1779.6 1268.2 675.57 1313.1 1425.2 TRUE FALSE FALSE 1302.448748 1347.180075 1258.162259 1187.764923 1531.023225 1410.4909 1303.782279 881.5481831 1169.056215 1474.725594 0.883180405 0.913512372 0.853150081 0.805414193 1.038174987 0.956442952 0.884084662 0.597770993 0.792727962 1 10.52623082 -4.26696078 3.363249893 0.932130575 0.555785436 0.562479594 0.0780951 0.144528107 2.704362708 0.010133406 0.138560038 5.41E-05 4.26696078 -0.376345139 LNGPGENVS(ph)EDEAQSSNQR ddPTM_HeLa_Curcumin_4h_R1 3 LNGPGENVSEDEAQSSNQR 19 0 H0Y9K3;D6R9W6;D6RJB0;A0A3B3ISF0;Q659C4-9;Q659C4-2;Q659C4;G3V0E9;A0A3B3IT29;A0A3B3ISF8;Q659C4-3 H0Y9K3 LARP1B La-related protein 1B 1 0 LNGPGENVS(1)EDEAQSSNQR;LNGPGENVS(0.999)EDEAQS(0.001)SNQR;LNGPGENVS(0.993)EDEAQS(0.007)SNQR ;; 337.71 2.07E-154 34615000 3996.85 3114.53 2909.13 3591.59 3630.53 3632.7 2708.49 1724.72 3891.05 3167.76 TRUE FALSE FALSE 3680.495105 3383.736095 3016.944917 3576.728952 3587.238301 2879.237071 2784.48294 2250.579188 3464.21155 3277.839424 1.122841796 1.032306851 0.920406563 1.091184921 1.094391102 0.878394789 0.849487293 0.686604466 1.056858223 1 11.67852947 -4.711885737 1.328645602 1.051688343 0.673480725 0.775452052 0.062043365 0.253633028 0.646133733 0.010458747 0.103515105 1.94E-05 4.711885737 -0.378207618 LNGPGENVSEDEAQS(ph)SNQR ddPTM_HeLa_Curcumin_4h_R1 1 LNGPGENVSEDEAQSSNQR 19 0 H0Y9K3;D6R9W6;D6RJB0;A0A3B3ISF0;Q659C4-9;Q659C4-2;Q659C4;G3V0E9;A0A3B3IT29;A0A3B3ISF8;Q659C4-3 H0Y9K3 LARP1B La-related protein 1B 1 0 LNGPGENVS(0.323)EDEAQS(0.668)S(0.009)NQR 226.08 7.89E-25 17261000 1929 1279.7 1505.3 1646.2 1705.2 1923 1121.3 812.33 1634.9 1497.8 TRUE FALSE FALSE 1776.317615 1390.311566 1561.087742 1639.388461 1684.866604 1524.148123 1152.76066 1060.005677 1455.55556 1549.848439 1.146123434 0.89706292 1.007251873 1.057773405 1.087117012 0.98341753 0.743789284 0.683941508 0.939159936 1 10.59791142 -4.777620318 2.913778468 1.052589474 0.691271351 0.728257091 0.072193751 0.089461094 1.508205075 0.010687676 0.045625275 1.67E-05 4.777620318 -0.361318123 LNGTDPEDVIR ddPTM_HeLa_Curcumin_4h_R1 4 LNGTDPEDVIR 11 0 J3QRS3;P19105;O14950;J3KTJ1;P24844 J3QRS3;P24844 MYL12A;MYL12B;MYL9 Myosin regulatory light chain 12A;Myosin regulatory light chain 12B;Myosin regulatory light polypeptide 9 0 0 ;;; ;;; 178.54 0.0014822 37938100 8529.7 7309.8 7639.3 8233.3 7934.5 11393.8 8879.2 8518.3 9115.5 7866.4 FALSE FALSE TRUE 7854.565245 7941.62654 7922.419178 8199.232786 7839.88627 9030.597445 9128.326455 11115.49046 8115.552456 8139.756814 0.964963134 0.975658944 0.973299247 1.007306849 0.963159766 1.109443151 1.12144953 1.365580165 0.997026403 1 12.99076998 -3.449635825 0.799259725 0.980759776 2.412403492 0.947968738 0.027132968 1.067879556 0.193601449 0.004124924 1.851303563 0.000355111 3.449635825 1.431643716 NLS(ph)NEELTK ddPTM_HeLa_Curcumin_4h_R1 2 NLSNEELTK 9 0 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 0 NLS(1)NEELTK;NLS(0.991)NEELT(0.009)K ; 99.732 0.013287 213650600 5260.3 4842.6 4800.1 4843.3 5178.8 6352.3 5348.1 8559.7 5929.2 4742.7 TRUE FALSE FALSE 4843.941704 5261.172766 4977.995929 4823.259708 5117.046192 5034.761375 5498.153292 11169.51313 5278.781594 4907.508472 0.987047039 1.072065957 1.014363186 0.982832681 1.042697373 1.025930246 1.120355334 2.276004859 1.075654097 1 12.26077504 -4.255534574 3.715363675 1.006356276 2.41949133 0.991418118 0.034683542 0.014846956 0.378721483 0.004353002 0.057966278 5.55E-05 4.255534574 1.413135054 up TQLAS(ph)WSDPTEETGPVAGILDTETLEK ddPTM_HeLa_Curcumin_4h_R1 1 TQLASWSDPTEETGPVAGILDTETLEK 27 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 T(0.036)QLAS(0.619)WS(0.343)DPT(0.002)EETGPVAGILDTETLEK 106.19 4.98E-08 50262000 2290.4 1765 2095.2 1805.4 2066.1 2903.3 2611.1 6879.8 2584.2 2104.5 TRUE FALSE FALSE 2109.112423 1917.558735 2172.849955 1797.929733 2041.463107 2301.122853 2684.360439 8977.419349 2300.719725 2177.631218 0.96853517 0.880570925 0.997804374 0.825635543 0.937469618 1.056709159 1.232697445 4.122561834 1.056524037 1 11.08854394 -4.255458717 3.806846207 0.970538139 4.460472228 0.994653666 0.069029569 0.013114765 0.363266251 0.009908018 0.128600735 5.55E-05 4.255458717 3.489934089 up LNISFPATGCQK ddPTM_HeLa_Curcumin_4h_R1 1 LNISFPATGCQK 12 0 P62753;A2A3R7 P62753 RPS6 40S ribosomal protein S6 0 0 168.3 1.47E-06 1674900 1303 827.72 1074.7 931.72 1168.1 1118.2 1119.9 1053.9 972.97 966.23 FALSE FALSE TRUE 1199.866175 899.2644286 1114.529327 927.8647895 1154.17117 886.2727153 1151.32138 1375.229258 866.2376253 999.8064206 1.200098489 0.899438541 1.114745119 0.92804444 1.154394637 0.886444313 1.151544295 1.375495526 0.866405343 1 9.965504982 -4.337041109 3.715399344 1.064076637 1.387485194 0.404794504 0.122905515 0.172866576 3.99760452 0.015492724 0.130339825 4.60E-05 4.337041109 0.323408557 LNLAQFLNEDLS(ph) ddPTM_HeLa_Curcumin_4h_R1 1 LNLAQFLNEDLS 12 0 Q9BPX3 Q9BPX3 NCAPG Condensin complex subunit 3 1 0 LNLAQFLNEDLS(1) 90.15 0.014993 20374000 1809.4 1407.9 1550.5 1828.3 1794.7 1294.7 1091.6 764.23 1909.1 1777.9 TRUE FALSE FALSE 1666.184081 1529.592603 1607.962894 1820.734979 1773.299375 1026.164626 1122.227358 997.2402089 1699.676506 1839.681893 0.905691406 0.831444071 0.874043986 0.989700984 0.963916306 0.5577946 0.610011634 0.54207209 0.923896959 1 10.84524061 -5.260880161 24.9997072 0.941825973 0.57396464 0.907405025 0.05210368 11.76066309 525739.4966 0.008898808 0.021272812 5.48E-06 5.260880161 -0.367861332 LNLEAINYMAADGDFK ddPTM_HeLa_Curcumin_4h_R1 1 LNLEAINYMAADGDFK 16 0 P09382 P09382 LGALS1 Galectin-1 0 0 194.98 4.25E-24 0 1214.6 1041.5 1241.8 1105.6 1017.1 2485.8 1462.9 1560.5 1389.6 1268.3 FALSE FALSE TRUE 1118.463128 1131.522619 1287.8222 1101.02532 1004.971747 1970.217059 1503.945037 2036.289266 1237.164357 1312.373331 0.852244634 0.862195682 0.981292572 0.838957402 0.765766664 1.501262646 1.145973483 1.551608234 0.942692394 1 10.35796247 -5.260078851 24.99999513 0.910913191 1.37425067 0.786601026 0.120689053 42.60837923 782926.4755 0.016642795 0.040017709 5.49E-06 5.260078851 0.46333748 LNLESS(ph)NSK ddPTM_HeLa_Curcumin_4h_R1 1 LNLESSNSK 9 0 I3L225;F6QPS0;G5EA36;P30260;P30260-2 I3L225 CDC27 Cell division cycle protein 27 homolog 1 0 LNLES(0.431)S(0.569)NSK 137.01 0.0028179 6217300 3422.2 3518.2 3816.8 3942.8 3905.2 4882.5 3884.1 1998.9 3623.8 3339.2 TRUE FALSE FALSE 3151.329259 3822.297531 3958.253966 3926.485738 3858.633041 3869.814463 3993.077392 2608.355408 3226.278206 3455.236951 0.912044327 1.106233114 1.145581047 1.136386822 1.116749182 1.119985262 1.155659496 0.754899141 0.933735733 1 11.75456894 -7.253622615 24.37416165 0.958465376 1.087724773 0.206092475 0.113057811 461.1885769 1438074.496 0.018134663 0.021981964 5.58E-08 7.253622615 0.129259397 LNLGTDSDS(ph)SPQK ddPTM_HeLa_Curcumin_4h_R1 2 LNLGTDSDSSPQK 13 0 Q16512;Q16512-2;K7EN76;Q16512-3 Q16512 PKN1 Serine/threonine-protein kinase N1 1 0 LNLGTDS(0.004)DS(0.498)S(0.498)PQK;LNLGTDS(0.012)DS(0.943)S(0.045)PQK ; 217.2 1.47E-13 147913000 11902.6 9298.8 10998 11032.4 10504.6 11831.7 8929.3 8092.5 11205.3 9792.4 TRUE FALSE FALSE 10960.49665 10102.54684 11405.59555 10986.75085 10379.33951 9377.672049 9179.832126 10559.866 9976.106624 10132.68517 1.081697148 0.997025632 1.125624192 1.084288189 1.024342445 0.92548736 0.905962435 1.042158699 0.984547181 1 13.30672892 -5.397916406 5.056010481 1.046385968 0.953372516 0.350208101 0.053253926 0.179486631 6.645756084 0.007620055 0.017359243 4.00E-06 5.397916406 -0.093013451 LNLGTDSDSS(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 1 LNLGTDSDSSPQK 13 0 Q16512;Q16512-2;K7EN76;Q16512-3 Q16512 PKN1 Serine/threonine-protein kinase N1 1 0 LNLGTDS(0.008)DS(0.401)S(0.591)PQK 108.23 0.0044272 82707000 4539.9 3701.7 3554.5 4255.3 4123.4 4905.5 3606.5 2658.7 4323.6 3899.7 TRUE FALSE FALSE 4180.562125 4021.658454 3686.232897 4237.692696 4074.231148 3888.044004 3707.688684 3469.325391 3849.311897 4035.214285 1.036019857 0.996640617 0.913516021 1.050177858 1.009669093 0.963528509 0.918833158 0.859762369 0.953929984 1 11.97842957 -4.61042138 1.338252944 1.010289654 0.841502248 0.523494609 0.039189588 0.349825918 0.829694166 0.005387347 0.067124183 2.45E-05 4.61042138 -0.168787406 LNLYELK(ac)EGR ddPTM_HeLa_Curcumin_4h_R1 2 LNLYELKEGR 10 1 A0A087WXQ8;A0A087WY10;A0A087WUL2;P49720 A0A087WXQ8 PSMB3 Proteasome subunit beta type-3 0 1 ; LNLYELK(1)EGR;LNLYELK(1)EGR 125.74 0.0020376 5335700 1135.92 688.56 910.28 922.73 978.03 1027.5 790.58 920.2 971.93 867.23 FALSE TRUE FALSE 1046.010733 748.0760582 944.0157776 918.9119878 966.367631 814.3849177 812.7615471 1200.764744 865.3117106 897.3661779 1.165645373 0.833635228 1.051985021 1.024010053 1.076893307 0.907527983 0.905718944 1.338098954 0.96427939 1 9.809552999 LNMGEIETLDDY ddPTM_HeLa_Curcumin_4h_R1 1 LNMGEIETLDDY 12 0 Q6Y7W6-4;Q6Y7W6-5;Q6Y7W6;I1E4Y6;Q6Y7W6-3 Q6Y7W6-4 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 0 0 157.34 0.0024816 2452100 2118 1727.4 1986.1 2064.6 1737.4 2281.2 1779 1709.6 2314 1781.7 FALSE FALSE TRUE 1950.358065 1876.708759 2059.706613 2056.057232 1716.68264 1808.053406 1828.913952 2230.84917 2060.159989 1843.613942 1.05789939 1.017951056 1.117211454 1.115231983 0.931150823 0.980711506 0.992026536 1.210041386 1.117457371 1 10.84832087 -9.317096836 0.957856955 0.998994905 1.048004078 0 0.084373459 1.63771412 2.602211009 0.056886366 0.013908409 4.82E-10 9.317096836 0.049009173 LNNLVLFDK ddPTM_HeLa_Curcumin_4h_R1 2 LNNLVLFDK 9 0 P62851 P62851 RPS25 40S ribosomal protein S25 0 0 ; ; 147.2 7.46E-06 1671110 1133.21 700.96 633.98 806.81 872.63 846.81 808.1 759.159 578.32 496.97 FALSE FALSE TRUE 1043.515233 761.547859 657.4758565 803.471634 862.2244572 671.1720605 830.7731111 990.6230844 514.8797429 514.2396705 2.029239074 1.48092009 1.278539744 1.56244584 1.67669767 1.305173636 1.615536799 1.926384021 1.001244697 1 9.0062971 -9.59220506 1.393749514 1.001069355 1.645816626 0.529465932 0.226983425 0.306112325 1.069527009 0.18303163 0.042779656 2.56E-10 9.59220506 0.644747271 LNNSS(ph)PNSSGGVK ddPTM_HeLa_Curcumin_4h_R1 1 LNNSSPNSSGGVK 13 0 O00472;H0Y8G1;O00472-2 O00472 ELL2 RNA polymerase II elongation factor ELL2 1 0 LNNS(0.363)S(0.635)PNS(0.003)SGGVK 195.94 3.74E-06 10875000 2653.1 2332.4 2167.9 2217.8 3110.8 2812.2 2583.4 2184.8 2291.4 2010.1 TRUE FALSE FALSE 2443.104335 2534.002263 2248.244281 2208.623331 3073.705742 2228.91802 2655.883251 2850.935462 2040.039153 2079.950825 1.174597161 1.218299121 1.080912228 1.061863244 1.477778082 1.071620537 1.276897136 1.370674454 0.980811242 1 11.0223337 -6.648584231 0.031454799 8.57E-10 2.361323859 0.431697196 0.117457248 115.1726878 1.977938605 70.10441936 77.79683563 2.25E-07 6.648584231 2.361323858 LNPEDIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 LNPEDIKK 8 1 P53396;P53396-2 P53396 ACLY ATP-citrate synthase 0 1 ; LNPEDIK(1)K;LNPEDIK(1)K 113.62 0.0015132 10642800 6956.6 8712.8 5734.5 6036.9 11637 14654.4 12847.1 11095.2 15220.1 6401 FALSE TRUE FALSE 6405.977769 9465.895609 5947.025615 6011.920907 11498.23638 11614.91225 13207.55505 14478.0754 13550.49311 6623.434274 0.967168617 1.429152192 0.897876444 0.907674276 1.735993127 1.753608743 1.994064484 2.185886476 2.045840956 1 12.69336374 -5.640354319 3.31392139 1.008336532 1.958357892 0.41798989 0.37250411 0.063484774 1.37283143 0.026345856 0.055824538 2.29E-06 5.640354319 0.95002136 LNQS(ph)AENGSSLPSAASSCAEAR ddPTM_HeLa_Curcumin_4h_R1 1 LNQSAENGSSLPSAASSCAEAR 22 0 Q8NB90-3;Q8NB90-2;Q8NB90 Q8NB90-3 SPATA5 Spermatogenesis-associated protein 5 1 0 LNQS(0.994)AENGS(0.003)S(0.003)LPSAASSCAEAR 148.64 9.37E-06 9874900 1665.1 1717.1 1639.5 1470.3 1476.9 2570.6 2088.4 856.23 1571.3 1179 TRUE FALSE FALSE 1533.305578 1865.518473 1700.261312 1464.216288 1459.288932 2037.428583 2146.994883 1117.290585 1398.932321 1219.970162 1.25683859 1.529150901 1.393690899 1.200206639 1.196167724 1.670064274 1.759874913 0.915834354 1.146693882 1 10.25263015 -8.362021869 0.571616269 0.995829807 1.404334193 0.183041525 0.237929212 0.763944092 0.536320861 0.141773268 0.0649623 4.34E-09 8.362021869 0.408504386 LNQS(ph)SPDNVTDTK ddPTM_HeLa_Curcumin_4h_R1 1 LNQSSPDNVTDTK 13 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 0 LNQS(0.927)S(0.073)PDNVTDTK 229.48 1.87E-19 139910000 9778.7 7716.7 8077.9 8291.5 8182.7 8837.6 6432.4 5204.3 8635.7 7102 TRUE FALSE FALSE 9004.705577 8383.697163 8377.27408 8257.19197 8085.126647 7004.58214 6612.875832 6791.067112 7688.385315 7348.793971 1.22533107 1.140826263 1.139952231 1.123611847 1.100197757 0.953160773 0.899858651 0.924106342 1.046210486 1 12.84329179 -5.21529685 3.090705259 1.115768277 0.913645835 0.696162783 0.056488182 0.1582612 3.018199753 0.012144852 0.033666249 6.09E-06 5.21529685 -0.202122443 LNQSAENGS(ph)SLPSAASSCAEAR ddPTM_HeLa_Curcumin_4h_R1 1 LNQSAENGSSLPSAASSCAEAR 22 0 Q8NB90-3;Q8NB90-2;Q8NB90 Q8NB90-3 SPATA5 Spermatogenesis-associated protein 5 1 0 LNQS(0.022)AENGS(0.728)S(0.249)LPS(0.001)AASSCAEAR 115.09 8.16E-06 9101300 962.04 809.47 781.44 902.99 997.72 1481 1045.4 633.13 804.69 828.11 TRUE FALSE FALSE 885.8935189 879.4369799 810.4008538 899.2536666 985.8228406 1173.823906 1074.73111 826.1684224 716.4175202 856.8867609 1.033851332 1.026316452 0.945750233 1.049442829 1.150470384 1.369870512 1.254227699 0.964151228 0.836070241 1 9.742960752 -5.727659168 3.490463337 1.01240376 1.208869643 0.429161138 0.112001443 0.152312254 3.855717954 0.013774248 0.028021288 1.87E-06 5.727659168 0.196465884 LNQSDSIEDPNS(ph)PAGRR ddPTM_HeLa_Curcumin_4h_R1 2 LNQSDSIEDPNSPAGRR 17 1 Q86VS8 Q86VS8 HOOK3 Protein Hook homolog 3 1 0 LNQSDSIEDPNS(1)PAGRR;LNQSDSIEDPNS(1)PAGRR ; 162.39 6.20E-05 33820000 2440.3 1733.88 1587.3 2291.57 2454.67 2725.2 2237.51 1798.36 2691.1 1936.16 TRUE FALSE FALSE 2247.14768 1883.748861 1646.126734 2282.088091 2425.399663 2159.962801 2300.288509 2346.671685 2395.893063 2003.441416 1.121643819 0.940256524 0.821649548 1.139084014 1.210616714 1.07812626 1.148168592 1.171320342 1.195888756 1 10.96826461 -6.039930799 24.99862648 1.029919499 1.150043388 0.309537451 0.098776297 526.7291846 329757.4071 0.014424594 0.02392285 9.12E-07 6.039930799 0.120123889 LNQSPSLAPVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 LNQSPSLAPVKR 12 1 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 0 1 LNQSPSLAPVK(1)R 107.97 0.0013726 2245700 1088.7 556.69 706.8 505.66 785.35 1272.4 791.54 790.5 821.41 708.6 FALSE TRUE FALSE 1002.528246 604.807803 732.9946298 503.5677129 775.9852142 1008.489897 813.7484821 1031.519811 731.3033781 733.2237973 1.3672882 0.824861121 0.999687452 0.686785828 1.058319734 1.375418939 1.109822792 1.406828058 0.997380855 1 9.5181098 -1.097534654 0.007812301 0.179368025 2.18942581 0 0.227678205 142425.2572 88.25412553 10138.89073 12705.55924 0.07988502 1.097534654 2.010057785 LNQVCFDDDGTSSPQDR ddPTM_HeLa_Curcumin_4h_R1 1 LNQVCFDDDGTSSPQDR 17 0 H3BVG0;Q8N1F7;Q8N1F7-2;H3BPA9 H3BVG0 NUP93 Nuclear pore complex protein Nup93 0 0 228.19 3.88E-21 8598300 549.18 604.3 566.63 628.05 589.29 727.74 514.71 543.12 768.05 780.36 FALSE FALSE TRUE 505.7118235 656.5329993 587.6298063 625.4512955 582.2631016 576.7985207 529.1513773 708.7147878 683.7968366 807.4774519 0.626286 0.813066665 0.727735251 0.774574317 0.721088992 0.71432152 0.655314122 0.87768988 0.846830874 1 9.657278164 -9.453475429 1.135346078 1.003046728 0.727145219 0.398725517 0.082441713 0.23032367 0.521583571 0.051007753 0.012094735 3.52E-10 9.453475429 -0.275901508 SVSENS(ph)LVAMDFSGQTGR ddPTM_HeLa_Curcumin_4h_R1 1 SVSENSLVAMDFSGQTGR 18 0 A0A2R8YCL1;Q13322-3;Q13322-2;Q13322-4;Q13322 A0A2R8YCL1 GRB10 Growth factor receptor-bound protein 10 1 0 SVS(0.01)ENS(0.988)LVAMDFS(0.002)GQTGR 140.89 0.00033735 6621600 1900.3 1725.9 1468.8 1639.5 1787.9 1643.3 1207.5 271.31 1634.3 1718.6 TRUE FALSE FALSE 1749.88925 1875.079106 1523.23502 1632.716183 1766.58046 1302.461056 1241.3792 354.03117 1455.021379 1778.321222 0.984011903 1.054409677 0.85655786 0.918122195 0.99339784 0.732410455 0.698062411 0.199081676 0.818199412 1 10.79630023 -4.36291106 1.083887809 0.983544502 7.95E-19 0.857553889 0.089558293 0.279913082 0.292277453 0.010185613 0.301186288 4.34E-05 4.36291106 -0.983544502 down SYS(ph)PSFQR ddPTM_HeLa_Curcumin_4h_R1 2 SYSPSFQR 8 0 Q9P227-2;Q9P227 Q9P227-2 ARHGAP23 Rho GTPase-activating protein 23 1 0 S(0.182)YS(0.636)PS(0.182)FQR;S(0.003)YS(0.734)PS(0.263)FQR ; 109.44 0.011459 72650000 8251.8 6976.3 7901.3 7949.5 8472.9 8054.5 4875.8 1088.35 8055.5 6698.4 TRUE FALSE FALSE 7598.661323 7579.300286 8194.129129 7916.607075 8371.866201 6383.905907 5012.601825 1420.182905 7171.831804 6931.168901 1.096303009 1.09350968 1.182214608 1.14217489 1.207857768 0.921043189 0.723197183 0.204898037 1.034721835 1 12.75888296 -4.361450708 1.593430064 1.076469175 2.80E-16 0.937810575 0.071208505 0.170218426 0.469255588 0.012125647 0.266186524 4.35E-05 4.361450708 -1.076469175 down VNPVTSLSENYTCS(ph)DSEESSEKDK ddPTM_HeLa_Curcumin_4h_R1 1 VNPVTSLSENYTCSDSEESSEKDK 24 1 Q14432 Q14432 PDE3A "cGMP-inhibited 3,5-cyclic phosphodiesterase A" 1 0 VNPVTSLSENY(0.045)T(0.207)CS(0.747)DS(0.002)EESSEKDK 132.48 7.46E-07 15135000 1895.9 1620.2 2006.4 1970.7 2150 2345.1 1245.3 289.55 1927.2 1451 TRUE FALSE FALSE 1745.837514 1760.242869 2080.758949 1962.545766 2124.362654 1858.699825 1280.239766 377.8324621 1715.790982 1501.422142 1.162789242 1.172383715 1.385858707 1.307124566 1.41490031 1.237959514 0.852684752 0.25164972 1.142777193 1 10.55211395 -4.355845287 2.609606181 1.155762223 0.15954818 0.827409049 0.134243857 0.153253266 1.518309407 0.024061693 0.300084048 4.41E-05 4.355845287 -0.996214043 down LNS(ph)FIQVDAPDQK ddPTM_HeLa_Curcumin_4h_R1 1 LNSFIQVDAPDQK 13 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 LNS(1)FIQVDAPDQK 124.46 0.0019122 0 1202.9 1213.9 1300.2 1521.5 1128.5 1741.8 1614.2 728.73 1168 1343.6 TRUE FALSE FALSE 1107.689196 1318.824107 1348.386556 1515.204436 1115.043375 1380.531046 1659.490108 950.9164223 1039.873322 1390.29 0.796732477 0.948596413 0.969859925 1.089847756 0.80202215 0.992980634 1.193628745 0.683969835 0.747954256 1 10.44117013 -7.017402087 23.79032054 0.902362661 0.966410969 0.060903719 0.147956689 1122.080895 1533992.592 0.023334353 0.028945584 9.61E-08 7.017402087 0.064048308 LNSEAS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 LNSEASPSR 9 0 Q13111;Q13111-3;Q13111-2;K7EJF1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 0 LNSEAS(0.5)PS(0.5)R 110.15 0.0091016 82379000 5246.7 5259.6 6269.5 5125.8 7048.5 5208.8 4193.5 2709.6 4555.9 4048.6 TRUE FALSE FALSE 4831.418159 5714.216388 6501.853185 5104.590798 6964.451241 4128.436165 4311.158324 3535.744567 4056.129168 4189.288549 1.153278917 1.364006399 1.552018466 1.218486323 1.662442479 0.985474292 1.029090805 0.843996427 0.968214321 1 12.03248954 -2.875418133 13.81515277 1.149017432 1.146024051 0 0.258097265 0 0 0.035102149 0 0.001332238 2.875418133 -0.00299338 LNSEAS(ph)PSREAINGQR ddPTM_HeLa_Curcumin_4h_R1 2 LNSEASPSREAINGQR 16 1 Q13111;Q13111-3;Q13111-2;K7EJF1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 0 LNSEAS(0.956)PS(0.044)REAINGQR;LNSEAS(0.694)PS(0.306)REAINGQR ; 187.78 1.73E-05 31259000 5213.3 4432.9 4752.6 4380.6 5273.7 4951.8 3997.7 2696.3 5351.3 4313.7 TRUE FALSE FALSE 4800.661804 4816.060123 4928.735537 4362.474238 5210.814572 3924.740862 4109.864703 3518.389458 4764.275778 4463.600754 1.075513261 1.078963014 1.10420618 0.977344184 1.16740158 0.879276861 0.920750965 0.788240179 1.067361541 1 12.12399228 -5.150556472 7.750519969 1.048063537 0.866141348 0.703882138 0.059912384 0.127147855 8.011461037 0.008321833 0.021355766 7.07E-06 5.150556472 -0.18192219 LNSEASPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 LNSEASPSR 9 0 Q13111;Q13111-3;Q13111-2;K7EJF1 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 0 LNSEAS(0.015)PS(0.985)R 89.356 0.020274 77661000 2339.8 2502.3 2727.7 2637.1 2757 2743.6 1577.7 1325.9 2214.6 2259.5 TRUE FALSE FALSE 2154.602361 2718.587662 2828.790962 2626.188379 2724.124576 2174.546433 1621.966016 1730.160806 1971.663921 2338.017457 0.921551015 1.162774749 1.209910111 1.123254393 1.165142958 0.93008135 0.693735631 0.740011928 0.843305902 1 11.19106999 -4.876531638 4.192908767 1.021332263 0.717329245 0.571481549 0.114433715 0.133501269 4.156806559 0.017476612 0.057738455 1.33E-05 4.876531638 -0.304003018 LNSMPMEERK ddPTM_HeLa_Curcumin_4h_R1 1 LNSMPMEERK 10 1 E7EW05;Q9NVU7-2;Q9NVU7 E7EW05 SDAD1 Protein SDA1 homolog 0 0 93.178 0.0099884 1977000 1124.4 1307.3 1069.3 1111.6 1837.7 2589.3 1544.2 911.29 1983.3 1103.9 FALSE FALSE TRUE 1035.402554 1420.297187 1108.929199 1107.000494 1815.786628 2052.249993 1587.526096 1189.138126 1765.736952 1142.260443 0.906450504 1.243409238 0.970819926 0.969131428 1.589643272 1.796656801 1.389810972 1.0410394 1.545826929 1 10.15767592 -5.768877647 24.94318652 0.980842048 1.474137092 0.217005041 0.265769337 86.03356574 288502.4244 0.029468248 0.054190393 1.70E-06 5.768877647 0.493295044 LNSS(ph)ENGEDR ddPTM_HeLa_Curcumin_4h_R1 2 LNSSENGEDR 10 0 Q7L4I2;Q7L4I2-2;H0YGP9;E1B6W4 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 1 0 LNS(0.102)S(0.898)ENGEDR;LNS(0.071)S(0.929)ENGEDR ; 113.52 0.00609 38322000 3457.1 3641.9 3607.9 3119.5 3186.4 3193.4 2265.3 1443.06 2996.6 3090.5 TRUE FALSE FALSE 3183.466887 3956.689608 3741.611948 3106.592336 3148.404261 2531.052843 2328.858221 1883.042351 2667.880477 3197.894645 0.995488357 1.237279538 1.17002352 0.971449244 0.984524073 0.791474743 0.728247325 0.588838145 0.834261529 1 11.64290669 -4.984387138 1.346523822 1.031099124 0.605671375 0.686075779 0.10502431 0.211711231 0.649706736 0.014421463 0.084984601 1.04E-05 4.984387138 -0.42542775 LNSSNSAS(ph)PHR ddPTM_HeLa_Curcumin_4h_R1 1 LNSSNSASPHR 11 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 LNSSNS(0.004)AS(0.996)PHR 109.99 0.0015327 0 515.75 615.89 449.1 428.54 808.74 749.52 535.06 412.84 606.98 524.76 TRUE FALSE FALSE 474.9278433 669.1247872 465.7440411 426.766815 799.0963037 594.0611032 550.0723436 538.7130155 540.3958126 542.9953709 0.874644368 1.232284515 0.857731145 0.785949269 1.471644781 1.094044507 1.01303321 0.992113459 0.995212559 1 9.084796089 LNSSSSSSSNSSNEREDFDSTSSS(ph)SSTPPLQPR ddPTM_HeLa_Curcumin_4h_R1 1 LNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPR 33 1 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 0 LNSSSSSSSNSSNEREDFDS(0.062)T(0.062)S(0.061)S(0.061)S(0.215)S(0.215)S(0.215)T(0.107)PPLQPR 82.211 6.18E-08 24282000 1252.8 878.6 1104.1 1141.2 1053.2 1481.8 1195.6 583.08 1316.5 1207.5 TRUE FALSE FALSE 1153.639558 954.542269 1145.018917 1136.478017 1040.641278 1174.457977 1229.145318 760.8584078 1172.083244 1249.460535 0.923310121 0.76396352 0.916410631 0.90957496 0.832872467 0.939972047 0.983740809 0.608949532 0.93807144 1 10.28708962 -13.52286394 0.021932104 2.158826785 3.20E-06 0.190555732 0.100722291 2168.985765 3.833688576 256.5660795 138.0413306 3.00E-14 13.52286394 -2.158823581 LNSSSSSSSNSSNEREDFDSTSSSSS(ph)TPPLQPR ddPTM_HeLa_Curcumin_4h_R1 1 LNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPR 33 1 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 0 LNSSSSSSSNSSNEREDFDS(0.022)T(0.022)S(0.022)S(0.022)S(0.022)S(0.117)S(0.386)T(0.386)PPLQPR 87.155 2.55E-08 22452000 802.26 920.37 893.1 862.31 836.87 983.66 710.06 446.78 970.28 728.26 TRUE FALSE FALSE 738.7602745 999.9226817 926.1990717 858.7419897 826.8908718 779.6378279 729.9823726 583.0011653 863.8427115 753.5669808 0.980351174 1.326919447 1.229086591 1.139569556 1.09730242 1.034596589 0.968702705 0.773655402 1.146338326 1 9.557591941 -4.276252338 1.983964612 1.052435722 0.696404245 0.380957586 0.115366263 0.744644625 3.156389621 0.019062926 0.475356227 5.29E-05 4.276252338 -0.356031477 LNSST(ph)EANVIK ddPTM_HeLa_Curcumin_4h_R1 1 LNSSTEANVIK 11 0 Q8NI08-2;Q8NI08;Q8NI08-7 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 0 LNS(0.013)S(0.334)T(0.652)EANVIK 149.69 0.001907 7590900 2052.7 2520.8 2400.7 2997.7 2827.4 2557.2 2173.4 1449.5 2671.5 2390.9 TRUE FALSE FALSE 1890.226629 2738.68672 2489.672054 2985.296312 2793.685102 2026.807894 2234.379755 1891.445877 2378.443134 2473.983597 0.764041698 1.106994696 1.006341375 1.206675871 1.129225394 0.81924872 0.903150594 0.764534526 0.961381933 1 11.27262022 -2.764268229 9.308175028 0.933326574 0.694074748 0 0.14996429 0 0 0.022309778 0 0.001720805 2.764268229 -0.239251826 LNTQEIFDDWAR ddPTM_HeLa_Curcumin_4h_R1 1 LNTQEIFDDWAR 12 0 Q14204 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 0 179.6 0.00090273 13502000 684.66 886.37 927.67 915.14 732.97 1170.4 710.16 712.7 790.88 1007.5 FALSE FALSE TRUE 630.4684386 962.9838732 962.0502663 911.3533932 724.2298115 927.6458469 730.0851783 929.9989491 704.1224427 1042.51055 0.604759768 0.92371619 0.922820653 0.874191051 0.694697825 0.889819146 0.700314427 0.892076295 0.675410376 1 10.02584627 -9.703418466 1.602556617 0.999711431 0.781605145 0 0.14727643 0.386289381 1.793246276 0.087636753 0.019431016 1.98E-10 9.703418466 -0.218106286 LNTS(ph)DFQK ddPTM_HeLa_Curcumin_4h_R1 5 LNTSDFQK 8 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 0 LNT(0.074)S(0.926)DFQK;LNT(0.086)S(0.914)DFQK;LNT(0.057)S(0.943)DFQK;LNT(0.101)S(0.899)DFQK;LNT(0.27)S(0.73)DFQK ;;;; 124.67 0.0068166 1567820000 26969.3 24549.8 25801.9 25096.1 24380.7 31097.8 27826.1 5335.99 27809.4 26268.6 TRUE FALSE FALSE 24834.65145 26671.77532 26758.14111 24992.25899 24089.97608 24647.76574 28606.82548 6962.908787 24758.7784 27181.43189 0.913662369 0.981249826 0.984427208 0.919460722 0.886265895 0.906786877 1.052439974 0.256164164 0.910871013 1 14.73033384 -4.256578631 24.99999575 0.955266747 0.256163879 0.945375297 0.050064533 81.75820636 420487.8595 0.00709766 0.078167571 5.54E-05 4.256578631 -0.699102869 LNVGAPDVTLR ddPTM_HeLa_Curcumin_4h_R1 1 LNVGAPDVTLR 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 105.17 0.0061799 2585800 1522.7 1525.8 1736.2 1627.4 1681 1657 1569.6 1069.2 1845.6 1492.1 FALSE FALSE TRUE 1402.176688 1657.683353 1800.545099 1620.66625 1660.955173 1313.319522 1613.638752 1395.194158 1643.142297 1543.950364 0.908174719 1.073663631 1.166193643 1.049688052 1.075782753 0.850622891 1.045136417 0.90365221 1.064245546 1 10.59241066 -2.485903539 14.4033167 0.985975799 0.656697999 0 0.0965741 0 0 0.01305256 0 0.003266604 2.485903539 -0.3292778 LNVTEQEK ddPTM_HeLa_Curcumin_4h_R1 1 LNVTEQEK 8 0 P06733;A0A2R8Y6G6;K7EM90;A0A2R8YEM5;A0A2R8Y879;A0A2R8Y6I8 P06733 ENO1 Alpha-enolase;Enolase 0 0 93.178 0.015675 0 2132.6 1926.4 2007.7 2356.4 2280.9 2816.3 2376.8 2208 2022.3 1973.3 FALSE FALSE TRUE 1963.80246 2092.909432 2082.107128 2346.649841 2253.701757 2232.167634 2443.486611 2881.209036 1800.45875 2041.872028 0.96176569 1.024995398 1.019705006 1.149263915 1.103742902 1.093196637 1.196689399 1.411062494 0.881768654 1 10.99567673 -1 0.390977984 0.982245604 7.247856867 0.856678248 0.052853716 13.93628914 0.16675919 0.01144785 67.54156604 0.1 1 6.265611263 LNYSDES(ph)PEAGK ddPTM_HeLa_Curcumin_4h_R1 1 LNYSDESPEAGK 12 0 Q9GZR1-2;Q9GZR1 Q9GZR1-2 SENP6 Sentrin-specific protease 6 1 0 LNYS(0.001)DES(0.999)PEAGK 177.39 0.00013067 28205000 2878 2411.5 2596.3 2710.6 2695.5 3812.8 2774.6 1305.3 3195.8 2779.3 TRUE FALSE FALSE 2650.203263 2619.939315 2692.521162 2699.384255 2663.357923 3021.982301 2852.447809 1703.279961 2845.228735 2875.880468 0.921527613 0.911004245 0.936242376 0.938628808 0.926101746 1.050802471 0.991852005 0.592263823 0.989341792 1 11.489788 -4.258442591 24.96421306 0.960236196 0.592263686 0.874300183 0.042142608 76.66228194 638587.7412 0.006502388 0.060988884 5.52E-05 4.258442591 -0.36797251 LPAEGPEPEADS(ph)QEQVHPK ddPTM_HeLa_Curcumin_4h_R1 1 LPAEGPEPEADSQEQVHPK 19 0 O75459 O75459 PAGE1 P antigen family member 1 1 0 LPAEGPEPEADS(1)QEQVHPK 119.43 0.00011511 9120900 2151.1 2203.4 2133.3 2102.7 2481.3 2630 2534.7 2595.7 2520.7 2074.6 TRUE FALSE FALSE 1980.838165 2393.852078 2212.361975 2093.999585 2451.712118 2084.508354 2605.81686 3387.116981 2244.185516 2146.692196 0.922739725 1.115135222 1.030591148 0.975454045 1.142088336 0.971032716 1.213875406 1.577830761 1.045415603 1 11.06789963 -1.000000073 0.791080222 0.98257507 143.8731716 0.833749582 0.073466391 117.1106865 0.399378216 0.011676518 29984.03462 0.099999983 1.000000073 142.8905966 LPATEK(ac)PVLLSK ddPTM_HeLa_Curcumin_4h_R1 1 LPATEKPVLLSK 12 1 A0A087X054;A0A494C039;Q9Y4L1 A0A087X054 HYOU1 Hypoxia up-regulated protein 1 0 1 LPATEK(1)PVLLSK 103.44 0.0003544 0 132.07 79.442 0 71.095 294.62 0 60.322 164.71 198.22 0 FALSE TRUE FALSE 121.6165201 86.30861249 0 70.80082773 291.1068489 0 62.01447297 214.9293208 176.4757619 0 0 LPATLLNAFPTAPS(ph)PRPPR ddPTM_HeLa_Curcumin_4h_R1 1 LPATLLNAFPTAPSPRPPR 19 1 Q93015;Q93015-2 Q93015 NAT6 N-acetyltransferase 6 1 0 LPATLLNAFPT(0.215)APS(0.785)PRPPR 61.256 0.0090436 7810000 1323.2 1127.7 1138 1178.4 1283.8 1376.6 1179.1 812.55 1739.6 1161.2 TRUE FALSE FALSE 1218.467324 1225.173363 1180.175281 1173.524093 1268.491523 1091.077643 1212.182373 1060.292754 1548.770232 1201.551614 1.014078222 1.019659371 0.982209393 0.976673894 1.055711223 0.90805724 1.008847526 0.882436295 1.288975201 1 10.23068291 -2.697093444 0.707831294 1.00575751 9.00E-13 0.136574797 0.096807739 13.17779119 0.802724022 0.005339383 17.33105452 0.002008661 2.697093444 -1.00575751 LPDGYEFK ddPTM_HeLa_Curcumin_4h_R1 2 LPDGYEFK 8 0 P09382 P09382 LGALS1 Galectin-1 0 0 ; ; 114.28 0.004124 38075000 15670.6 11726.8 12850.6 12310.2 13066.8 18657 13672.6 12522.6 13649.4 11324.4 FALSE FALSE TRUE 14430.25547 12740.41234 13326.85454 12259.26365 12910.98694 14787.32789 14056.21636 16340.68309 12152.09497 11717.92206 1.231468805 1.087258669 1.137305273 1.046197747 1.101815397 1.261941138 1.199548545 1.394503481 1.03705204 1 13.51642914 -1 0.020712314 1.78E-10 2.689638521 0.479500022 0.083469684 2193.113788 3.535703492 169.1417528 310.1519948 0.1 1 2.689638521 LPDLS(ph)PVENK ddPTM_HeLa_Curcumin_4h_R1 3 LPDLSPVENK 10 0 E7EPN9;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;Q9Y520-2;A0A2R8Y7F4;A0A2R8YET2;H7C5N8 E7EPN9 PRRC2C Protein PRRC2C 1 0 LPDLS(1)PVENK;LPDLS(1)PVENK;LPDLS(1)PVENK ;; 150.51 0.00075613 118677100 10031.2 9626.3 10630.2 11241.3 12625.9 11215.3 10404.4 13040.7 8374.8 8567.1 TRUE FALSE FALSE 9237.219935 10458.35448 11024.16456 11194.78648 12475.34439 8889.120358 10696.31946 17016.7494 7456.105393 8864.806087 1.042010377 1.179761224 1.243587785 1.262834897 1.407289033 1.002742786 1.206605013 1.919585068 0.841090636 1 13.11387336 -2.036174144 1.207273308 1.084650179 199.9849479 0.683039506 0.159103564 149.8292495 1.183021906 0.023859961 81482.02075 0.009200806 2.036174144 198.9002977 LPDS(ph)DDDEDEETAIQR ddPTM_HeLa_Curcumin_4h_R1 2 LPDSDDDEDEETAIQR 16 0 H3BRF9;Q96K21-2;Q96K21;H3BRM1;Q96K21-4;Q96K21-3 H3BRF9;Q96K21-3 ZFYVE19 Abscission/NoCut checkpoint regulator 1 0 LPDS(1)DDDEDEETAIQR;LPDS(1)DDDEDEETAIQR ; 244.54 2.51E-30 335370000 1200.96 1142.69 1295.19 1108.65 1301 1223.79 1164.64 764.78 1180.01 1258.96 TRUE FALSE FALSE 1105.902749 1241.459032 1343.190881 1104.0627 1285.486425 969.962159 1197.316664 997.9579014 1050.565855 1302.708766 0.848925545 0.952982788 1.031075337 0.847513066 0.986779592 0.744573295 0.919097725 0.766063703 0.806447214 1 10.34729888 -8.051521439 0.018544206 1.846577074 2.82E-06 0.009662586 0.096053686 509.999479 5.335178828 272.9469079 257.558235 8.88E-09 8.051521439 -1.846574259 LPEASQS(ph)PLVLK ddPTM_HeLa_Curcumin_4h_R1 2 LPEASQSPLVLK 12 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 0 LPEAS(0.034)QS(0.966)PLVLK;LPEAS(0.002)QS(0.998)PLVLK ; 161.87 0.00017359 88981000 3923.9 3307.1 2871.3 3411.2 3243.9 4388.3 3679.9 4233.8 3951.2 3357.5 TRUE FALSE FALSE 3613.319175 3592.950988 2977.712904 3397.085358 3205.218611 3478.117114 3783.14809 5524.66613 3517.763245 3474.172875 1.040051634 1.03418889 0.857099808 0.977811261 0.922584663 1.001135303 1.088934899 1.590210484 1.012546978 1 11.76245383 -4.248388091 2.854010236 0.998383865 1.706515142 0.917804756 0.054289473 0.095681415 1.0511327 0.008268157 0.158704006 5.64E-05 4.248388091 0.708131278 LPEGPVDS(ph)EDDEEEDEEIDRTDPLQGR ddPTM_HeLa_Curcumin_4h_R1 2 LPEGPVDSEDDEEEDEEIDRTDPLQGR 27 1 E9PCH4;Q8TEU7;Q8TEU7-4;B7Z7Y1;Q8TEU7-2;Q8TEU7-5;Q8TEU7-3;D6RD23;D6RIH0;D6RB02;Q8TEU7-6 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 0 LPEGPVDS(1)EDDEEEDEEIDRTDPLQGR;LPEGPVDS(0.965)EDDEEEDEEIDRT(0.035)DPLQGR ; 125.04 5.99E-09 62114000 856.42 656.98 507.39 680.28 999.89 763.74 699.39 485.44 565.9 609.47 TRUE FALSE FALSE 788.6334533 713.7664238 526.1943197 677.4651816 987.9669648 605.3317149 719.0130011 633.4484213 503.8221858 630.6490371 1.250510834 1.131796581 0.834369497 1.074234862 1.566587605 0.959855132 1.14011591 1.004438894 0.79889472 1 9.300693543 LPELDPRGS(ph)DEENLDSETSASTESLLEER ddPTM_HeLa_Curcumin_4h_R1 2 LPELDPRGSDEENLDSETSASTESLLEER 29 1 M0R0P8;Q13459-2;Q13459;M0R300;M0R240;M0QXP0 M0R0P8 MYO9B Unconventional myosin-IXb 1 0 LPELDPRGS(0.951)DEENLDS(0.009)ET(0.009)S(0.009)AS(0.01)T(0.01)ES(0.003)LLEER;LPELDPRGS(0.987)DEENLDS(0.003)ET(0.002)S(0.003)AS(0.003)T(0.001)ESLLEER ; 54.311 0.0017816 72588000 3976.2 3771.4 3582 3927.4 4137.1 4113.4 3276.3 3221.6 3877.5 3308.4 TRUE FALSE FALSE 3661.479574 4097.383011 3714.752071 3911.149459 4087.767785 3260.234472 3368.22416 4203.85101 3452.147951 3423.366654 1.069555191 1.19688699 1.085116625 1.142486288 1.194078285 0.952347441 0.98389232 1.227987369 1.008407308 1 11.7412001 -8.253921517 1.10422391 1.012570192 1.103243489 0.184955505 0.085315485 0.571551845 1.440806971 0.024849806 0.017589102 5.57E-09 8.253921517 0.090673297 LPGDAAASSSAVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 LPGDAAASSSAVKK 14 1 F5H148;H3BMT1;Q9NYV6-2;Q9NYV6 F5H148 RRN3 RNA polymerase I-specific transcription initiation factor RRN3 0 1 LPGDAAASSSAVK(1)K 165.58 2.37E-05 3883800 1341.8 1071.8 1685.4 1375.6 1178.7 1359.7 1072.9 519.86 1342.8 1182.5 FALSE TRUE FALSE 1235.595114 1164.441616 1747.862407 1369.908132 1164.644772 1077.682893 1103.002686 678.3629209 1195.4982 1223.591787 1.009809912 0.951658575 1.428468567 1.119579378 0.951824607 0.880753618 0.901446625 0.55440297 0.977040065 1 10.25690661 -3.911662834 1.001709319 1.037041068 8.90E-11 0.54588321 0.138201932 2.1729423 1.054679138 0.021717525 2.854419488 0.000122557 3.911662834 -1.037041068 LPGEGNAGLLGLGPEAAAPGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 LPGEGNAGLLGLGPEAAAPGKR 22 1 P25440-2;P25440;A0A0G2JK44;A0A140T9E9;H0Y6K2;A0A0G2JHL0;A0A140T9V2;A0A140T9F7;U3KQA6;E9PIQ3;E9PKQ9;A0A140T9X8;H0Y799 P25440-2 BRD2 Bromodomain-containing protein 2 0 1 LPGEGNAGLLGLGPEAAAPGK(1)R 141.6 2.16E-06 1491800 67.091 0 126.89 0 65.856 135.18 0 0 0 0 FALSE TRUE FALSE 61.78067656 0 131.592655 0 65.07071021 107.1421442 0 0 0 0 0 LPGSGAVQAAS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 LPGSGAVQAASPER 14 0 Q86U90 Q86U90 YRDC "YrdC domain-containing protein, mitochondrial" 1 0 LPGSGAVQAAS(1)PER 149.99 0.0005129 41453000 353.98 476.65 577.13 485.78 384.43 706.69 437.45 396.97 755.4 380.63 TRUE FALSE FALSE 325.9621095 517.8495021 598.5189455 483.7699711 379.8459233 560.114528 449.7236697 518.0043256 672.5345099 393.8568642 0.827615662 1.314816496 1.519635685 1.22828879 0.964426313 1.42212712 1.141845453 1.315209592 1.707560718 1 8.621527609 -7.256929426 24.98811947 0.918596283 1.269052766 0 0.289561384 216.6106947 1200167.164 0.025623848 0.030817915 5.53E-08 7.256929426 0.350456482 LPIGDVATQYFADRDMFCAGR ddPTM_HeLa_Curcumin_4h_R1 2 LPIGDVATQYFADRDMFCAGR 21 1 Q99832-3;Q99832;Q99832-2;Q99832-4 Q99832-3 CCT7 T-complex protein 1 subunit eta 0 0 ; ; 84.895 0.00073434 20723600 1046.89 729.06 758.36 711.21 693.63 1130.89 889.39 871.64 974.1 928.62 FALSE FALSE TRUE 964.0275518 792.0766978 786.4654887 708.2672015 685.3589153 896.3306662 914.3438897 1137.399023 867.2436671 960.8894759 1.003265803 0.824316134 0.818476535 0.737095388 0.71325468 0.932813491 0.951559896 1.183693913 0.90254258 1 9.908226688 -7.275093759 22.57946888 1.001542203 0.870647315 0.070313143 0.128721739 277.0110607 458076.1202 0.022153054 0.025428035 5.31E-08 7.275093759 -0.130894889 LPLLPPES(ph)PGPLR ddPTM_HeLa_Curcumin_4h_R1 1 LPLLPPESPGPLR 13 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;A0A669KAX5 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 LPLLPPES(1)PGPLR 116.98 0.0027853 41435000 1631.5 1354.1 1221.6 1489.8 1219.9 1777.3 852.2 710.71 1739.7 1183.2 TRUE FALSE FALSE 1502.365053 1471.14237 1266.873571 1483.635602 1205.353489 1408.667946 876.1104384 927.4022073 1548.859263 1224.316112 1.227105515 1.201603373 1.034760188 1.211807627 0.984511661 1.150575355 0.715591692 0.757485913 1.265081173 1 10.25776039 -4.759804059 24.99998561 1.111970666 0.736538666 0.730821713 0.095819059 16.8907091 258192.1879 0.01396677 0.047300369 1.74E-05 4.759804059 -0.375432 LPLPS(ph)PALEYTLGSR ddPTM_HeLa_Curcumin_4h_R1 2 LPLPSPALEYTLGSR 15 0 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 0 LPLPS(0.984)PALEY(0.003)T(0.011)LGS(0.002)R;LPLPS(1)PALEYTLGSR ; 137.39 0.00058463 162726000 1958.3 1214.64 1647.56 1617.86 2197.1 2645.3 1685.4 2213.2 1880.8 1449.83 TRUE FALSE FALSE 1803.298489 1319.628069 1708.620023 1611.165724 2170.901017 2096.634961 1732.687788 2887.994492 1674.480946 1500.211485 1.202029519 0.879628028 1.138919439 1.073959065 1.447063324 1.397559599 1.154962354 1.925058248 1.116163263 1 10.55095018 -1 0.504172445 1.08153442 24.43505952 0.665494323 0.162133112 45.27987938 0.430108727 0.031743833 1129.076758 0.1 1 23.3535251 LPLQES(ph)EEEEREER ddPTM_HeLa_Curcumin_4h_R1 1 LPLQESEEEEREER 14 1 P23497;E9PHV6;P23497-7;P23497-6;P23497-2;P23497-3;P23497-4;P23497-5;C9JBL0 P23497 SP100 Nuclear autoantigen Sp-100 1 0 LPLQES(1)EEEEREER 68.329 0.015536 48345000 1035.2 1011.9 827.98 872.54 1096.9 941.14 860.75 712.25 857.13 903.61 TRUE FALSE FALSE 953.2628277 1099.364127 858.6656672 868.9296607 1083.820184 745.9369552 884.9003284 929.4117462 763.1049834 935.0103802 1.019521117 1.175777457 0.918348807 0.929326218 1.159153103 0.797784678 0.946406957 0.994012223 0.816146002 1 9.868838571 -5.253400978 24.98514746 1.017743257 0.916101871 0.109517504 0.111631185 723.7263872 2249497.264 0.012177023 0.030473003 5.58E-06 5.253400978 -0.101641386 LPLQLDDAVRPEAEGEEEGR ddPTM_HeLa_Curcumin_4h_R1 2 LPLQLDDAVRPEAEGEEEGR 20 1 C9J7S3;C9JLC1;P14868-2;P14868 C9J7S3 DARS "Aspartate--tRNA ligase, cytoplasmic" 0 0 ; ; 77.137 0.003019 19955700 2971.6 2191.12 2727.4 3028.4 2423.09 1955.57 2011.84 2030.48 2525.84 2511.9 FALSE FALSE TRUE 2736.394724 2380.510649 2828.479843 3015.869283 2394.196234 1549.962738 2068.286816 2649.564005 2248.761671 2599.188338 1.052788166 0.915866932 1.08821658 1.160311948 0.921132262 0.596325674 0.795743342 1.019381307 0.865178425 1 11.34384546 -5.520499138 24.98469712 1.03057803 0.795629346 0.36334192 0.123241215 56.76411845 595993.2251 0.015605658 0.031642606 3.02E-06 5.520499138 -0.234948684 QGS(ph)EIQDSPDFR ddPTM_HeLa_Curcumin_4h_R1 2 QGSEIQDSPDFR 12 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;H0Y952;Q8WX93-6 Q8WX93-3 PALLD Palladin 1 0 QGS(0.988)EIQDS(0.012)PDFR;QGS(0.999)EIQDS(0.001)PDFR ; 125.36 0.0030177 19583200 2423.23 2235.94 2072.3 2362.07 2007.36 3089.3 3473.5 13331.1 2136.09 1991.19 TRUE FALSE FALSE 2231.428789 2429.20469 2149.101261 2352.29638 1983.423543 2448.544356 3570.957062 17395.69102 1901.766271 2060.383704 1.083016131 1.179005971 1.043058755 1.141678793 0.962647656 1.18839241 1.733151478 8.442937587 0.923015586 1 11.00869732 -4.255455467 3.704057807 1.066800301 9.282656067 0.99843882 0.086993113 0.008524893 0.21520809 0.014443671 0.193120955 5.55E-05 4.255455467 8.215855766 up LVS(ph)PGSANETSSILVESVTR ddPTM_HeLa_Curcumin_4h_R1 1 LVSPGSANETSSILVESVTR 20 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;A0A0A0MT44 O75369-8 FLNB Filamin-B 1 0 LVS(0.992)PGS(0.008)ANETSSILVESVTR 158.15 1.25E-05 74203000 1988 1525.3 1710.7 1633.4 1947.2 2212.6 1998.2 3699 1508.3 1599.4 TRUE FALSE FALSE 1830.647702 1657.140135 1774.100047 1626.641424 1923.980912 1753.681819 2054.264114 4826.808072 1342.843264 1654.979031 1.106145557 1.00130582 1.071977357 0.982877362 1.16254096 1.059639902 1.241262926 2.916537298 0.811395938 1 10.69259722 -4.255262919 3.563009958 1.054338991 3.147165013 0.973893299 0.092248693 0.019775315 0.438623191 0.007947498 0.111178672 5.56E-05 4.255262919 2.092826022 up LPLVPES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 LPLVPESPR 9 0 C9J0I9;Q86WB0;Q86WB0-2;Q86WB0-3 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 LPLVPES(1)PR;LPLVPES(1)PR;LPLVPES(1)PR ;; 134.3 0.0032424 72204000 3308.86 2906.23 2953.82 3298.58 3522.54 4565.6 3346.56 3512.02 3627.6 3361.47 TRUE FALSE FALSE 3046.96024 3157.431571 3063.291168 3284.93135 3480.536011 3618.643095 3440.455467 4582.818731 3229.661356 3478.280832 0.875996041 0.907756367 0.880691156 0.944412343 1.00064836 1.040353919 0.98912527 1.317552823 0.928522311 1 11.7641587 -1.000000027 0.867800747 0.936481573 148.4554572 0.842650502 0.048189698 253.2563527 0.609977699 0.009316619 73882.37122 0.099999994 1.000000027 147.5189756 LPLVPES(ph)PRR ddPTM_HeLa_Curcumin_4h_R1 1 LPLVPESPRR 10 1 C9J0I9;Q86WB0;Q86WB0-2;Q86WB0-3 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 LPLVPES(1)PRR 145.81 0.0005178 102960000 4936.9 3656.6 3663.3 4454.6 4117.6 5133.8 4440.5 4402.7 4417.2 4400.8 TRUE FALSE FALSE 4546.139156 3972.660211 3799.065121 4436.168046 4068.500309 4068.99201 4565.088479 5745.062962 3932.644211 4553.727472 0.998333603 0.872397445 0.834275908 0.974183912 0.893443961 0.893551938 1.002494881 1.261617652 0.863609918 1 12.15283224 -4.274656424 3.945014926 0.962937003 1.285672791 0.657455141 0.068670001 0.117937787 3.729763482 0.010062703 0.106597076 5.31E-05 4.274656424 0.322735788 VQMTS(ph)PSSTGSPMFK ddPTM_HeLa_Curcumin_4h_R1 2 VQMTSPSSTGSPMFK 15 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 0 VQMT(0.235)S(0.621)PS(0.091)S(0.026)T(0.026)GSPMFK;VQMT(0.066)S(0.83)PS(0.063)S(0.013)T(0.027)GS(0.001)PMFK ; 144.68 0.00049514 41787000 2786.1 1949.63 2414.2 2813.1 2528.8 2920.2 3530.3 8415.8 2915.7 2333.9 TRUE FALSE FALSE 2565.577245 2118.14733 2503.672376 2801.460138 2498.645712 2314.517603 3629.350717 10981.73868 2595.855005 2415.002851 1.062349572 0.877078604 1.036716116 1.160023532 1.034634684 0.95839125 1.502834961 4.547298432 1.074886932 1 11.23780918 -4.255051655 3.153390361 1.027439604 5.101789223 0.99518692 0.073029385 0.016814229 0.252789825 0.010485213 0.169877652 5.56E-05 4.255051655 4.074349619 up LPNNSSRPS(ph)TPTINVLESK ddPTM_HeLa_Curcumin_4h_R1 1 LPNNSSRPSTPTINVLESK 19 1 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 0 LPNNS(0.001)S(0.002)RPS(0.496)T(0.496)PT(0.005)INVLESK 56.298 0.012546 48477000 1791.5 1628.8 1565.1 1621.2 2222.5 1424.3 1197.5 580.39 1771.9 1609 TRUE FALSE FALSE 1649.700885 1769.586214 1623.103983 1614.491904 2195.998139 1128.884125 1231.098627 757.3482392 1577.527003 1664.91263 0.990863337 1.062870316 0.974888384 0.969715692 1.318987014 0.678044063 0.739437376 0.454887677 0.947513386 1 10.70123076 -5.095348918 8.22997774 1.015771374 0.624503394 0.711446264 0.120636229 0.117230263 9.110964159 0.015455225 0.039635575 8.03E-06 5.095348918 -0.39126798 LPNSIAS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 LPNSIASR 8 0 H7C055;Q9ULT0;Q9ULT0-4;G5E9G4 H7C055 TTC7A Tetratricopeptide repeat protein 7A 1 0 LPNS(0.02)IAS(0.98)R 106.16 0.012418 15241000 1834.9 1958.6 1787.7 1702.2 1776.4 2381.3 2320.4 2257 2196.1 2407.9 TRUE FALSE FALSE 1689.665729 2127.892657 1853.953735 1695.156747 1755.21759 1887.391537 2385.504179 2945.14891 1955.193324 2491.574346 0.678151841 0.854035385 0.744089269 0.680355676 0.704461255 0.757509621 0.957428456 1.182043359 0.784722048 1 11.28284191 -4.41064555 2.810623687 0.811241213 1.19722948 0.619532729 0.096619331 0.248974555 3.132966126 0.019331346 0.183525086 3.88E-05 4.41064555 0.385988267 LPPKVESLESLYFT(ph)PIPAR ddPTM_HeLa_Curcumin_4h_R1 2 LPPKVESLESLYFTPIPAR 19 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 LPPKVESLES(0.017)LY(0.077)FT(0.906)PIPAR;LPPKVESLES(0.005)LY(0.006)FT(0.988)PIPAR ; 81.379 0.0034051 43761000 2569.88 1864.58 2317.66 2517.77 2769.6 4776.8 3851.7 1972.63 3167 2503.79 TRUE FALSE FALSE 2366.471286 2025.745987 2403.554518 2507.352135 2736.574329 3786.037834 3959.768336 2574.075806 2819.588023 2590.796516 0.91341457 0.781900846 0.927728019 0.967791997 1.056267566 1.461341256 1.528398047 0.993546112 1.088309331 1 11.33917999 -5.43408427 4.074368926 0.942972626 1.345454372 0.56234102 0.149798514 0.11083255 3.320110254 0.019820045 0.045635493 3.68E-06 5.43408427 0.402481746 LPPSGSKPVAASTCSGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 LPPSGSKPVAASTCSGKK 18 2 G3V3N7;O43663-3;O43663-2;O43663-4;O43663;H0YNE4;H3BSJ8 G3V3N7 PRC1 Protein regulator of cytokinesis 1 0 1 LPPSGSKPVAASTCSGK(1)K 93.181 0.0033236 3737800 3477.4 3288.1 3246.6 3076.8 3038.7 4240.8 3211.5 2205.5 3456 2990.5 FALSE TRUE FALSE 3202.160121 3572.308713 3366.921852 3064.069017 3002.465487 3361.210276 3301.606047 2877.946797 3076.885446 3094.419652 1.034817665 1.154435763 1.088062458 0.990191817 0.970283874 1.086216691 1.066954847 0.930044118 0.994333604 1 11.59545315 -4.248919882 23.69555833 1.033072415 0.930043983 0.260256224 0.05486709 1158.81539 2193197.041 0.007926081 0.177566519 5.64E-05 4.248919882 -0.103028432 LPS(ph)DTDDSDASEDPGPGAER ddPTM_HeLa_Curcumin_4h_R1 1 LPSDTDDSDASEDPGPGAER 20 0 Q9UJK0 Q9UJK0 TSR3 Ribosome biogenesis protein TSR3 homolog 1 0 LPS(0.861)DT(0.137)DDS(0.002)DASEDPGPGAER 201.18 1.29E-13 12993000 339.98 269.18 328.42 309.14 470.98 327.87 275.31 440.43 361.07 196.84 TRUE FALSE FALSE 313.0702243 292.4467198 340.5915341 307.8608606 465.3638711 259.8660661 283.0344576 574.7150795 321.4615244 203.6801753 1.537067727 1.435813374 1.672187946 1.511491534 2.284777447 1.275853508 1.389602386 2.821654481 1.578266141 1 7.670161756 -1 0.060927832 1.48E-13 5.078787985 0.250803354 0.431867197 222.9958666 1.024479467 17.40344709 100.732893 0.1 1 5.078787985 RFS(ph)EGVLQSPSQDQEK ddPTM_HeLa_Curcumin_4h_R1 1 RFSEGVLQSPSQDQEK 16 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 RFS(1)EGVLQSPSQDQEK 182.09 1.96E-05 15037000 2264.4 1433 1895.4 1971.7 2155.2 2445.8 2327.2 4537.9 1999.5 1810.6 TRUE FALSE FALSE 2085.170351 1556.862135 1965.645191 1963.541628 2129.500648 1938.51351 2392.494969 5921.48482 1780.159853 1873.518215 1.112970418 0.830983186 1.049173248 1.04805046 1.136631942 1.034691574 1.277006516 3.160623031 0.950169493 1 10.87153429 -4.254927342 3.432236459 1.044233118 3.444344679 0.982972043 0.08393415 0.026794757 0.525922118 0.011507652 0.168576052 5.56E-05 4.254927342 2.400111562 up LPS(ph)GSGAASPTGSAVDIR ddPTM_HeLa_Curcumin_4h_R1 1 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 LPS(0.972)GS(0.026)GAAS(0.002)PTGSAVDIR 175.19 2.66E-06 632610000 236.75 0 260.25 227.75 250.23 170.39 351.37 2994.9 240.51 105.43 TRUE FALSE FALSE 218.0109877 0 269.8950939 226.8076308 247.2461707 135.0491933 361.2284965 3908.031223 214.1266547 109.0936847 1.99838321 0 2.473975417 2.079017054 2.266365569 1.237919443 3.311176973 35.82270812 1.96277773 1 6.769423777 -4.260810413 4.845888856 1.552863121 37.69145682 0.995391973 0.694992147 0.007994476 0.544712398 0.098534886 0.969658262 5.49E-05 4.260810413 36.1385937 LPS(ph)IVVEPTEGEVESGELR ddPTM_HeLa_Curcumin_4h_R1 2 LPSIVVEPTEGEVESGELR 19 0 B5MBX5;B5MCP4;Q53QV2 B5MBX5 LBH Protein LBH 1 0 LPS(1)IVVEPTEGEVESGELR;LPS(1)IVVEPTEGEVESGELR ; 214.34 3.12E-18 15854600 961.86 650.2 742.12 652.69 1156.04 2142.1 3282.8 1194.76 699.88 775.82 TRUE FALSE FALSE 885.727766 706.4003908 769.62362 649.9893417 1142.254978 1697.804314 3374.906533 1559.036824 623.104915 802.7796873 1.103326081 0.87994303 0.958698423 0.809673379 1.422874789 2.114906917 4.20402582 1.942048172 0.776184207 1 9.648860302 -5.140437725 2.768991849 1.024032893 3.08461696 0.701055993 0.545992506 0.09263443 1.36179652 0.066440987 0.200883493 7.24E-06 5.140437725 2.060584067 LPS(ph)PGLHGQR ddPTM_HeLa_Curcumin_4h_R1 1 LPSPGLHGQR 10 0 P10070;P10070-4;P10070-3;P10070-2;P10070-1 P10070 GLI2 Zinc finger protein GLI2 1 0 LPS(1)PGLHGQR 112.84 0.0017528 0 1639.9 1315.8 1159.1 1282.6 1320.8 1203.3 877.7 549.01 1586 1075.7 TRUE FALSE FALSE 1510.100185 1429.531889 1202.057266 1277.292941 1305.050323 953.722016 902.3258998 716.4006217 1412.019768 1113.080495 1.356685515 1.284302344 1.079937409 1.147529713 1.172467156 0.856831128 0.810656465 0.643619779 1.268569321 1 10.12034221 -5.011660904 1.474210989 1.176761784 0.673771989 0.778202624 0.103494434 0.229954982 0.884272054 0.0214763 0.111269756 9.74E-06 5.011660904 -0.502989795 LPS(ph)PTPENK ddPTM_HeLa_Curcumin_4h_R1 1 LPSPTPENK 9 0 H0Y3A3;A0A3B3ITG3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-2;Q5VWQ8-5;Q5VWQ8 H0Y3A3 DAB2IP Disabled homolog 2-interacting protein 1 0 LPS(0.953)PT(0.047)PENK 107.45 0.009972 13872000 1762.7 1961.5 1942.9 1820.3 2434.2 2015.4 2040.5 1855 1718.3 1585.7 TRUE FALSE FALSE 1623.180435 2131.04332 2014.905583 1812.768081 2405.173755 1597.383322 2097.750938 2420.580961 1529.806789 1640.802957 0.989259818 1.298780765 1.227999727 1.104805469 1.46585167 0.973537569 1.278490467 1.47524171 0.93235253 1 10.68018628 -7.26741282 24.16130463 0.994928238 1.250954119 0.457642515 0.142250264 202.2786229 818173.1914 0.022301709 0.025873129 5.40E-08 7.26741282 0.256025881 LPS(ph)PTVAR ddPTM_HeLa_Curcumin_4h_R1 1 LPSPTVAR 8 0 O95425-3;A0A6I8PIX7;O95425 O95425-3 SVIL Supervillin 1 0 LPS(0.982)PT(0.018)VAR 94.409 0.018325 5651700 2282.8 2065 2101.4 2127.4 2120.4 2549.4 2157 1172.4 2379.2 2218.2 TRUE FALSE FALSE 2102.113971 2243.489399 2179.279733 2118.597382 2095.115615 2020.625702 2217.519615 1529.859363 2118.207712 2295.282285 0.915841152 0.977435069 0.949460442 0.923022583 0.912792134 0.880338648 0.966120651 0.666523405 0.922852813 1 11.16445588 -3.804884462 1.877184725 0.950832284 9.49E-09 0.811221167 0.038341044 1.521598667 1.683127759 0.006298046 3.90632424 0.000156717 3.804884462 -0.950832274 LPS(ph)SPVYEDAASFK ddPTM_HeLa_Curcumin_4h_R1 1 LPSSPVYEDAASFK 14 0 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 1 0 LPS(0.942)S(0.058)PVYEDAASFK 177.93 0.00016238 9333300 2025.3 1818.1 1988.9 2161.2 1998.7 1782.7 2001.5 2277.2 2186.7 1732.9 TRUE FALSE FALSE 1864.995368 1975.248463 2062.610384 2152.257527 1974.866808 1412.947925 2057.656703 2971.507797 1946.824481 1793.118146 1.040085045 1.101571844 1.150292516 1.200287628 1.101359 0.78798373 1.147529909 1.657173457 1.085720138 1 10.80825483 -4.289606961 3.914373327 1.039221205 1.699666091 0.732585639 0.107113009 0.080863151 2.436013824 0.01489258 0.143913563 5.13E-05 4.289606961 0.660444887 LPSANQGS(ph)PFK ddPTM_HeLa_Curcumin_4h_R1 1 LPSANQGSPFK 11 0 Q56NI9;E5RFE4;E5RFP7;E5RIE3 Q56NI9 ESCO2 N-acetyltransferase ESCO2 1 0 LPSANQGS(1)PFK 88.224 0.019325 30383000 2241.6 2197.4 1901 2358.7 1700.2 1771.1 1264.2 679.75 1796.4 1848.1 TRUE FALSE FALSE 2064.174995 2387.333465 1971.452732 2348.940324 1679.926225 1403.753896 1299.67005 887.0026458 1599.339414 1912.321337 1.079408023 1.248395559 1.030921265 1.228318839 0.878474863 0.734057539 0.679629529 0.463835564 0.836334032 1 10.90110925 -5.118810688 1.454915561 1.066781548 0.536018468 0.734941742 0.121412198 0.145070863 0.553167051 0.015214172 0.069127125 7.61E-06 5.118810688 -0.53076308 LPSAQT(ph)PNGTDYVASGK ddPTM_HeLa_Curcumin_4h_R1 1 LPSAQTPNGTDYVASGK 17 0 E7EPN9;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;Q9Y520-2;A0A2R8Y7F4;A0A2R8YET2;H7C5N8 E7EPN9 PRRC2C Protein PRRC2C 1 0 LPS(0.039)AQT(0.837)PNGT(0.123)DY(0.001)VASGK 91.093 0.011199 24989000 2151.2 1852.6 1931.4 2077.5 1914.7 2986.2 2429.5 1497.2 2211.8 1894.9 TRUE FALSE FALSE 1980.93025 2012.730489 2002.979383 2068.903855 1891.868453 2366.828459 2497.665231 1953.689388 1969.171074 1960.747634 1.010293327 1.026511752 1.021538595 1.055160705 0.964870961 1.207105095 1.273833097 0.996400227 1.004296035 1 10.93718814 -5.25969432 24.99778392 1.00947571 1.170584841 0.490059366 0.068530247 82.38667911 1180166.118 0.008744187 0.02109272 5.50E-06 5.25969432 0.161109131 LPSDT(ph)DDSDASEDPGPGAER ddPTM_HeLa_Curcumin_4h_R1 1 LPSDTDDSDASEDPGPGAER 20 0 Q9UJK0 Q9UJK0 TSR3 Ribosome biogenesis protein TSR3 homolog 1 0 LPS(0.021)DT(0.978)DDS(0.001)DASEDPGPGAER 149.19 0.0001254 9967500 613.07 425.34 473.49 630.17 526.2 613.03 555.34 691.97 434.77 505.28 TRUE FALSE FALSE 564.5448626 462.1044943 491.0379559 627.5625235 519.9254087 485.8806677 570.9213458 902.9484676 387.0768187 522.8384424 1.07976923 0.883838021 0.939177222 1.200299122 0.994428425 0.929313203 1.091965126 1.727012389 0.740337334 1 9.030221411 -4.266010547 4.125324215 1.022677372 1.782860566 0.76360116 0.12288454 0.056646374 2.100762394 0.01169216 0.126468951 5.42E-05 4.266010547 0.760183193 QSS(ph)FEPEFVISPR ddPTM_HeLa_Curcumin_4h_R1 1 QSSFEPEFVISPR 13 0 A0A0A0MSU3;Q9H9A7 A0A0A0MSU3 RMI1 RecQ-mediated genome instability protein 1 1 0 QS(0.238)S(0.762)FEPEFVISPR 111.81 0.0036616 2880200 688.17 409.2 532.38 486.84 464.69 617.28 632.6 1413.8 549.58 359.45 TRUE FALSE FALSE 633.7006183 444.5694246 552.1104711 484.8255851 459.1488752 489.2491698 650.3490534 1844.861112 489.292449 371.9408607 1.703767145 1.195269118 1.484403918 1.30350181 1.234467421 1.315395057 1.748528119 4.960092602 1.315511418 1 8.538929438 -4.254800721 3.371776898 1.332581903 5.464308892 0.974861447 0.174296139 0.04983682 0.923819624 0.035630062 0.533543571 5.56E-05 4.254800721 4.13172699 up LPSGSGAAS(ph)PTGSAVDIR ddPTM_HeLa_Curcumin_4h_R1 5 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 LPSGSGAAS(0.987)PT(0.011)GS(0.001)AVDIR;LPSGSGAAS(0.989)PT(0.008)GS(0.002)AVDIR;LPSGSGAAS(0.763)PT(0.234)GS(0.003)AVDIR;LPSGS(0.007)GAAS(0.837)PT(0.156)GSAVDIR;LPS(0.026)GS(0.088)GAAS(0.886)PTGSAVDIR ;;;; 239.7 7.96E-32 6163450000 4050.59 3061.735 3828.611 3502.46 3828.82 4358.49 3322.74 3973.28 3900.387 3107.202 TRUE FALSE FALSE 3729.981527 3326.377731 3970.502692 3487.967749 3783.163822 3454.490044 3415.967142 5184.714781 3472.524304 3215.177038 1.160116996 1.03458618 1.234925058 1.084844693 1.176658012 1.074432295 1.062450715 1.612575208 1.080041398 1 11.65068246 -4.259497228 24.97717681 1.091520713 1.612575387 0.837849955 0.06741634 55.13086476 708959.0176 0.010731374 0.0933366 5.50E-05 4.259497228 0.521054674 LPSRPPLPGSGGSQSGAK(ac)MR ddPTM_HeLa_Curcumin_4h_R1 1 LPSRPPLPGSGGSQSGAKMR 20 2 Q9Y570-4;Q9Y570 Q9Y570-4 PPME1 Protein phosphatase methylesterase 1 0 1 LPSRPPLPGSGGSQSGAK(1)MR 61.87 0.0079783 2846500 0 222.55 285.87 153.55 274.18 421.29 270.92 109.21 177.17 237.53 FALSE TRUE FALSE 0 241.7862303 296.4645937 152.9146508 270.9105826 333.9097051 278.5212861 142.5076263 157.7348943 245.7841498 0 0.983734022 1.206198992 0.622150171 1.102229671 1.358548569 1.13319466 0.57980804 0.641761865 1 7.941248072 -7.046105069 24.64497192 0.525887629 1.01718546 0.290496042 0.321724199 394.8098048 211040.5993 0.07064886 0.086528817 8.99E-08 7.046105069 0.491297831 LPSS(ph)PASPSPK ddPTM_HeLa_Curcumin_4h_R1 1 LPSSPASPSPK 11 0 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 LPS(0.004)S(0.987)PAS(0.009)PSPK 116.03 0.0047167 6874100 2227.2 2387.6 2023 2152.2 2250.3 1963.6 1328.4 1445 2341.8 1812.5 TRUE FALSE FALSE 2050.91477 2593.973505 2097.97416 2143.294767 2223.466642 1556.327226 1365.671329 1885.573848 2084.910399 1875.48424 1.093538792 1.383095336 1.118630653 1.142795402 1.185542696 0.829826875 0.728169984 1.005379735 1.111665113 1 10.87304742 -5.249449464 24.22112123 1.092661767 0.841829935 0.523133556 0.120385049 366.8430596 741065.5513 0.018622703 0.047032304 5.63E-06 5.249449464 -0.250831832 SRS(ph)GEGEVSGLMR ddPTM_HeLa_Curcumin_4h_R1 2 SRSGEGEVSGLMR 13 1 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 0 S(0.012)RS(0.988)GEGEVSGLMR;S(0.001)RS(0.999)GEGEVSGLMR ; 137.73 0.010845 323300000 2894.1 2100.56 2138.8 2208.71 2355.29 2888.5 4490.4 17390.1 968.11 2025.7 TRUE FALSE FALSE 2665.028931 2282.123046 2218.065809 2199.570943 2327.204705 2289.39254 4616.388539 22692.26144 861.9107551 2096.092924 1.271426901 1.088750895 1.058190591 1.049367095 1.110258366 1.092219011 2.202377807 10.82598065 0.411198733 1 11.03348696 -4.254750826 3.408840658 1.120859451 12.14681168 0.993399729 0.238397503 0.009698645 0.18616488 0.018872873 0.279105603 5.56E-05 4.254750826 11.02595223 up LPSSPASPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 LPSSPASPSPK 11 0 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 LPS(0.002)S(0.07)PAS(0.3)PS(0.628)PK 128.57 0.0030596 36765000 2523.4 2443.2 2244.7 2630.1 2408.6 2686.5 1958.1 981.11 2617.7 2235.1 TRUE FALSE FALSE 2323.670227 2654.379321 2327.890557 2619.217343 2379.879018 2129.289617 2013.039016 1280.245923 2330.544859 2312.769559 1.004713253 1.147705923 1.006538048 1.132502516 1.029016924 0.92066657 0.870401899 0.553555333 1.007685721 1 11.17540581 -4.042544058 1.203584292 1.024174871 0.140455223 0.869808515 0.057282511 0.632729287 0.538965897 0.008917843 0.787548941 9.07E-05 4.042544058 -0.883719648 LRDDFEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 LRDDFEKK 8 2 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 0 1 LRDDFEK(1)K 81.95 0.0088542 4260400 3074.9 2509.2 2520.1 2406.4 2817.8 4505.9 3936.7 4785.1 4224.4 2916.7 FALSE TRUE FALSE 2831.51842 2726.084067 2613.497123 2396.442954 2784.199575 3571.325548 4047.153207 6244.054962 3760.993889 3018.055108 0.938193081 0.903258546 0.865954076 0.794035519 0.922514492 1.183320191 1.340980553 2.068900248 1.24616475 1 11.55940343 -4.074808705 1.184092812 0.941904789 2.975861926 0.8865375 0.120181952 0.346809904 0.300229676 0.012432458 0.960468564 8.42E-05 4.074808705 2.033957136 up LPTPTSSVPAQK(ac)TER ddPTM_HeLa_Curcumin_4h_R1 2 LPTPTSSVPAQKTER 15 1 Q9BTA9-2;Q9BTA9;Q9BTA9-3 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 0 1 ; LPTPTSSVPAQK(1)TER;LPTPTSSVPAQK(1)TER 154.23 1.32E-06 2329600 0 0 132.86 0 0 56.14 130.38 0 151 0 FALSE TRUE FALSE 0 0 137.7839085 0 0 44.49593117 134.0381119 0 134.4356778 0 0 LPVDLAEELGHR ddPTM_HeLa_Curcumin_4h_R1 6 LPVDLAEELGHR 12 0 J3QRG6;P42771;P42771-4;K7ES20;K7ENC6;P42771-2 J3QRG6 CDKN2A Cyclin-dependent kinase inhibitor 2A 0 0 ;;;;; ;;;;; 229 4.81E-19 68543000 24961.25 20366.92 21851.6 21289.01 21830.81 28284.7 22351.15 18427.95 24003.63 21317.57 FALSE FALSE TRUE 22985.54072 22127.34581 22661.43952 21200.92172 21570.49185 22418.13439 22978.26311 24046.54712 21370.49184 22058.35397 1.042033361 1.003127697 1.02734046 0.96112891 0.977883113 1.016310393 1.041703436 1.090133342 0.968816253 1 14.42903752 -4.387648787 2.262702501 1.012223574 1.098688922 0.495885823 0.026542622 0.332930055 2.382447603 0.003829778 0.050968119 4.10E-05 4.387648787 0.086465348 LQAALDDEEAGGRPAMEPGNGS(ph)LDLGGDSAGR ddPTM_HeLa_Curcumin_4h_R1 5 LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1X7SBS1 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 0 LQAALDDEEAGGRPAMEPGNGS(0.999)LDLGGDS(0.001)AGR;LQAALDDEEAGGRPAMEPGNGS(0.999)LDLGGDS(0.001)AGR;LQAALDDEEAGGRPAMEPGNGS(1)LDLGGDSAGR;LQAALDDEEAGGRPAMEPGNGS(0.998)LDLGGDS(0.002)AGR;LQAALDDEEAGGRPAMEPGNGS(0.999)LDLGGDS(0.001)AGR ;;;; 90.211 3.02E-08 1126110000 9527.1 7623.99 8020.51 9301.6 8139.55 11799.2 12465.8 12268.1 10871.6 9112.2 TRUE FALSE FALSE 8773.019982 8282.973724 8317.757156 9263.112444 8042.491182 9351.912916 12815.5568 16008.58721 9679.012679 9428.848272 0.930444496 0.878471419 0.882160463 0.982422474 0.852966444 0.991840429 1.359185812 1.69783061 1.02653181 1 13.20286584 -4.54142808 2.181420565 0.945863382 1.721118497 0.951979548 0.055261784 0.059520321 0.464893422 0.008254182 0.070964758 2.87E-05 4.54142808 0.775255115 LQAALDDEEAGGRPAMEPGNGSLDLGGDS(ph)AGR ddPTM_HeLa_Curcumin_4h_R1 1 LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1X7SBS1 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 0 LQAALDDEEAGGRPAMEPGNGS(0.215)LDLGGDS(0.785)AGR 52.717 0.010903 10192000 911.4 983.87 677.34 782.25 448.9 1014.4 606.58 867.05 725.34 742.13 TRUE FALSE FALSE 839.2617283 1068.911339 702.4428162 779.0132568 443.5471607 804.0020054 623.5990023 1131.409554 645.7720167 767.9189623 1.09290403 1.391958516 0.914735605 1.01444722 0.577596312 1.046988087 0.812063555 1.473344987 0.840937714 1 9.584810263 LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR ddPTM_HeLa_Curcumin_4h_R1 1 LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR 32 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1X7SBS1 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 0 88.108 2.76E-07 12852000 720.8 909.53 552.75 809.38 789.05 1022 656.28 715.18 1123.1 880.31 FALSE FALSE TRUE 663.7479194 988.1457204 573.2354012 806.031 779.6410941 810.0256797 674.6934505 933.2350897 999.8987399 910.900707 0.728672087 1.084800695 0.629306133 0.884872516 0.855901294 0.889257933 0.74068825 1.024519009 1.097703331 1 9.831149991 -9.62350364 1.434606902 1.000069239 0.835136981 0.221850873 0.133381457 0.541948055 2.001781687 0.08526743 0.019457604 2.38E-10 9.62350364 -0.164932258 LQADPKPIS(ph)PQQK ddPTM_HeLa_Curcumin_4h_R1 2 LQADPKPISPQQK 13 1 H7C1N2;J3KR05;O75128-2;O75128-6;O75128-3;O75128;O75128-7 H7C1N2;O75128-3 COBL Protein cordon-bleu 1 0 LQADPKPIS(1)PQQK;LQADPKPIS(1)PQQK ; 101.01 0.0058885 65306000 4993.5 4208.7 3836.3 4777.5 4523.9 5390.5 4407.2 3845 5042.9 4617.1 TRUE FALSE FALSE 4598.259206 4572.481274 3978.476653 4757.731971 4469.955447 4272.449537 4530.854171 5017.3228 4489.706487 4777.543881 0.962473463 0.957077818 0.832745183 0.995853118 0.935617874 0.894277403 0.948364742 1.050188742 0.939752014 1 12.22205341 -8.124563885 1.023271654 0.992814656 0.942091739 0 0.056757159 0.664781495 1.464356105 0.015213951 0.011314251 7.51E-09 8.124563885 -0.050722917 LQAEEVAQQK ddPTM_HeLa_Curcumin_4h_R1 2 LQAEEVAQQK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 179.8 1.06E-15 5422400 2530.3 1907.19 2841.2 2705.3 2934.8 3179 2245.6 2324.8 2377.7 2702.9 FALSE FALSE TRUE 2330.024085 2072.039005 2946.497371 2694.106185 2899.804427 2519.639565 2308.605492 3033.620818 2116.872259 2796.825574 0.83309596 0.740853854 1.053514885 0.963272866 1.036819905 0.900892637 0.82543778 1.084665718 0.756883904 1 11.44957457 LQALAEEPSQPHT(ph)RSPAK ddPTM_HeLa_Curcumin_4h_R1 1 LQALAEEPSQPHTRSPAK 18 1 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 0 LQALAEEPS(0.378)QPHT(0.408)RS(0.214)PAK 52.862 0.014567 8840200 2796.4 2105.6 1732.6 2598.5 2292.4 3268.7 1736.5 847.75 3327.9 2450.9 TRUE FALSE FALSE 2575.061989 2287.598682 1796.81168 2587.748096 2265.064627 2590.734774 1785.221516 1106.225072 2962.837696 2536.068593 1.015375529 0.902025556 0.708502793 1.020377802 0.893140128 1.021555482 0.703932662 0.436196827 1.168279795 1 11.30837805 -4.485876075 2.49532147 0.972555375 0.420250561 0.68404857 0.1142485 0.131732555 1.35996283 0.014295173 0.123799832 3.27E-05 4.485876075 -0.552304814 LQALK(ac)DTANR ddPTM_HeLa_Curcumin_4h_R1 1 LQALKDTANR 10 1 P29401;P29401-2;E9PFF2;F8W888;F8WAX4 P29401 TKT Transketolase 0 1 LQALK(1)DTANR 126.71 0.0018933 4008300 1058.9 1050.3 878.72 785.99 1170.4 1986.3 1437.1 1447 2203.1 913.63 FALSE TRUE FALSE 975.0869477 1141.083252 911.2861362 782.7377816 1156.443744 1574.31899 1477.421158 1888.183639 1961.425442 945.3785745 1.031424843 1.207011966 0.963937793 0.827962261 1.223259946 1.665278897 1.56278257 1.997277799 2.074751316 1 9.884748358 -5.297542516 2.376419186 1.014442624 1.761782921 0.266473958 0.360395045 0.074958519 0.821090883 0.018325568 0.05171179 5.04E-06 5.297542516 0.747340297 LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER ddPTM_HeLa_Curcumin_4h_R1 1 LQALKEEPQTVPEMPGETPPLSPIDMESQER 31 1 P05412 P05412 JUN Transcription factor AP-1 1 0 LQALKEEPQTVPEMPGET(0.082)PPLS(0.795)PIDMES(0.123)QER 58.087 0.00048265 11104000 2857.9 2385.2 2315 2631.5 2415.7 3374.9 2737 1437.6 2645.6 2618.4 TRUE FALSE FALSE 2631.694199 2591.36606 2400.795936 2620.61155 2386.894355 2674.907697 2813.792854 1875.917622 2355.384299 2709.389205 0.971323793 0.956439206 0.886102274 0.967233333 0.880971383 0.987273328 1.038534017 0.692376576 0.869341435 1 11.40375194 -4.252963934 24.92948973 0.971858474 0.69237643 0.637859264 0.056443744 396.399027 1165932.83 0.006654096 0.103291612 5.59E-05 4.252963934 -0.279482043 GLS(ph)VDSAQEVK ddPTM_HeLa_Curcumin_4h_R1 2 GLSVDSAQEVK 11 0 H0Y4W2;F2Z2U4;Q9Y4A5-2;Q9Y4A5 H0Y4W2 TRRAP Transformation/transcription domain-associated protein 1 0 GLS(1)VDSAQEVK;GLS(0.987)VDS(0.013)AQEVK ; 117.07 0.0045804 10996600 1297.41 863 1313.05 1530.82 1619.64 1972.54 3170.2 16111.9 1298.03 1324.49 TRUE FALSE FALSE 1194.718629 937.5938745 1361.712788 1524.485872 1600.326851 1563.412969 3259.14728 21024.34414 1155.639357 1370.515929 0.871729109 0.684117459 0.993576769 1.112344512 1.167682051 1.140747755 2.378044072 15.34045953 0.84321483 1 10.42050338 -4.25464895 3.576505362 0.975277842 17.11539084 0.998777719 0.149813701 0.009314039 0.20895 0.028931575 0.405153009 5.56E-05 4.25464895 16.140113 up LQANGPVAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 LQANGPVAKK 10 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2;S4R3C2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 1 ; LQANGPVAK(1)K;LQANGPVAK(1)K 193.41 9.86E-21 14083100 7223 5826.9 6757.5 6554.3 7053.4 8756.5 7243.9 6696.7 8008.4 6401.9 FALSE TRUE FALSE 6651.291928 6330.551272 7007.938895 6527.180043 6969.292812 6940.303194 7447.144338 8738.493002 7129.898556 6624.365548 1.004064748 0.955646428 1.057903409 0.985329085 1.052069479 1.047693269 1.124204919 1.319144141 1.076314177 1 12.69356657 -1.000001349 0.723494328 1.000951759 48.77703368 0.869504093 0.035192289 46.04313163 0.207816841 0.003759746 3576.239983 0.099999689 1.000001349 47.77608192 LQDAEIAR ddPTM_HeLa_Curcumin_4h_R1 2 LQDAEIAR 8 0 R4GN98;P06703 R4GN98 S100A6 Protein S100;Protein S100-A6 0 0 ; ; 155.07 8.62E-06 161658000 11129.2 8603 9686.3 10166.7 10427.1 12157.7 9617.6 10304 10602.8 11012.4 FALSE FALSE TRUE 10248.31208 9346.604986 10045.2828 10124.63289 10302.76364 9636.055974 9887.443972 13445.64217 9439.699367 11395.08008 0.899362883 0.820231619 0.881545608 0.888509148 0.904141399 0.845633019 0.867694119 1.179951529 0.828401319 1 13.47612344 -9.058930878 0.979814258 0.996659589 0.903467714 0 0.107781183 0.825136728 1.500176253 0.049269409 0.017024044 8.73E-10 9.058930878 -0.093191875 LQDEFENR ddPTM_HeLa_Curcumin_4h_R1 1 LQDEFENR 8 0 H0Y3P2;D3DQV9;P78344-2;P78344;H0YCH5;H0YEC5;H0YD77 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 0 0 146.79 0.019566 24827000 2260.1 2063.5 2366.5 1982.6 2213.1 2639.2 2019.7 2415.1 2598.8 2558.8 FALSE FALSE TRUE 2081.2107 2241.859745 2454.204572 1974.396527 2186.710228 2091.80017 2076.367346 3151.452872 2313.718142 2647.71811 0.78603938 0.846713907 0.926913089 0.745697406 0.825884833 0.79003885 0.784210124 1.190252414 0.873853653 1 11.37053382 -9.46619103 1.185654018 1.000554424 0.846793788 0.005599086 0.126519716 0.637961916 1.595147347 0.080452192 0.019545547 3.42E-10 9.46619103 -0.153760636 LQDEIQNMKEEMAR ddPTM_HeLa_Curcumin_4h_R1 2 LQDEIQNMKEEMAR 14 1 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 0 ; ; 185.2 4.82E-05 143313000 4694.3 3794.7 3820.4 4261 4238.8 5604.4 4569.4 3450.2 4906 4221.1 FALSE FALSE TRUE 4322.741202 4122.696959 3961.987385 4243.369111 4188.255078 4441.984265 4697.605066 4502.150097 4367.824074 4367.782911 0.989687741 0.94388779 0.907093476 0.971515572 0.958897263 1.016988334 1.075512488 1.030763247 1.000009424 1 12.09268544 -5.004142157 4.9939707 0.980532173 1.052521085 0.547174609 0.030250401 0.125111394 9.180381966 0.004890691 0.01424025 9.91E-06 5.004142157 0.071988912 LQDGTPQAALS(ph)PLT(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 2 LQDGTPQAALSPLTPAR 17 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 2 0 LQDGT(0.016)PQAALS(0.984)PLT(1)PAR;LQDGTPQAALS(1)PLT(1)PAR ; 140.96 0.0015237 3823000 2646.3 2067.73 2359.62 2503.3 2504.3 4819.8 4659.1 2135 2861.2 2196.8 TRUE FALSE FALSE 2436.842563 2246.455368 2447.069593 2492.942008 2474.437858 3820.11915 4789.821807 2785.951672 2547.333518 2273.138636 1.072016692 0.988261486 1.076515771 1.096695981 1.088555629 1.680548247 2.107140202 1.225596902 1.120623915 1 11.15046996 -5.265519376 4.897275981 1.040888708 1.721345792 0.651496194 0.202750425 0.067661018 4.908024267 0.025348162 0.062142669 5.43E-06 5.265519376 0.680457084 LQDGTPQAALS(ph)PLTPAR ddPTM_HeLa_Curcumin_4h_R1 1 LQDGTPQAALSPLTPAR 17 0 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6 A0A087WVP4 SMTN Smoothelin 1 0 LQDGTPQAALS(0.997)PLT(0.003)PAR 126.43 0.00037543 8141700 2153.7 2121.5 2406.9 2148.2 1934.2 3098 2049.7 1595.8 2782.6 2087.7 TRUE FALSE FALSE 1983.232372 2304.873007 2496.101831 2139.311318 1911.135928 2455.439878 2107.209066 2082.352074 2477.355742 2160.24742 0.918057975 1.066948622 1.155470345 0.99030847 0.884683815 1.136647523 0.975448019 0.96394147 1.146792594 1 11.07698084 -7.26046758 24.99131695 0.961305156 1.025496267 0 0.098030358 143.9781068 3702626.173 0.013704308 0.016277759 5.49E-08 7.26046758 0.064191111 LQDSSDPDT(ph)GSEEEGSSRLSPPHSPR ddPTM_HeLa_Curcumin_4h_R1 2 LQDSSDPDTGSEEEGSSRLSPPHSPR 26 1 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF0 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 0 LQDS(0.001)S(0.004)DPDT(0.399)GS(0.083)EEEGS(0.217)S(0.225)RLS(0.069)PPHS(0.001)PR;LQDS(0.002)S(0.007)DPDT(0.508)GS(0.111)EEEGS(0.143)S(0.143)RLS(0.085)PPHS(0.002)PR ; 65.428 0.00098897 28902000 3393.8 2403.7 2497.8 2720.1 2785.5 4527.2 3439.1 2005.13 3161.4 2748.7 TRUE FALSE FALSE 3125.177149 2611.465117 2590.370665 2708.844947 2752.284732 3588.207688 3535.59189 2616.484907 2814.602329 2844.21712 1.098782905 0.918166584 0.910749973 0.952404416 0.967677436 1.261580089 1.243080869 0.919931495 0.989587718 1 11.47381589 -5.278689349 24.769939 1.015507855 1.151685837 0.298215709 0.104262313 751.336 1078873.169 0.015652562 0.035079208 5.26E-06 5.278689349 0.136177982 TLGTPTQPGST(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 TLGTPTQPGSTPR 13 0 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 0 TLGT(0.002)PT(0.055)QPGS(0.078)T(0.864)PR 123.95 0.0062119 11040000 3406.7 2920.3 3159 3246.5 2828.5 3959.2 3623.4 5198.8 3315.4 3190.4 TRUE FALSE FALSE 3137.0561 3172.717719 3276.075319 3233.066843 2794.771985 3138.017291 3725.062852 6783.890188 2951.708915 3301.266163 0.95025846 0.961060867 0.992369339 0.979341466 0.846575783 0.950549618 1.128373984 2.05493585 0.894114188 1 11.68880374 -4.254498635 2.998487026 0.966233615 2.243336537 0.979799567 0.047430139 0.036006508 0.463888096 0.006382023 0.110450166 5.57E-05 4.254498635 1.277102922 up LQDYEEK ddPTM_HeLa_Curcumin_4h_R1 2 LQDYEEK 7 0 E7EQR4;P15311 E7EQR4 EZR Ezrin 0 0 ; ; 115.49 0.010289 13841800 10821.6 9027.1 9460.3 10263.8 9552.9 13175.8 9981.2 11003.8 12996.7 9030.4 FALSE FALSE TRUE 9965.058941 9807.3623 9810.90704 10221.33112 9438.987907 10442.99056 10261.24561 14358.80796 11570.99453 9344.205728 1.066442588 1.049566179 1.049945531 1.093868373 1.010143417 1.117589966 1.09813995 1.536653664 1.238306911 1 13.18985632 LQEDKEQMAQQLAEETQGFQR ddPTM_HeLa_Curcumin_4h_R1 1 LQEDKEQMAQQLAEETQGFQR 21 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 99.313 0.0010654 41653000 880.65 770.86 857.9 1028.4 859.17 996.27 855.25 667.29 808.75 866.13 FALSE FALSE TRUE 810.9456232 837.4897035 889.6945287 1024.144753 848.9249589 789.6323717 879.2460132 870.7436492 720.0321484 896.227953 0.904843037 0.934460592 0.992710086 1.142727974 0.947219908 0.881061977 0.981051763 0.971564931 0.803402913 1 9.807721914 -6.749107596 24.68204355 0.952263911 0.986412346 0.09451533 0.080226053 532.5764312 1065947.543 0.011503876 0.016199579 1.78E-07 6.749107596 0.034148435 LQEDPNYS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 2 LQEDPNYSPQR 11 0 P46379-3;P46379;P46379-2;P46379-5;A0A0G2JK23;A0A024RCR6;A0A0G2JL47;H0Y710;P46379-4;H0Y4L1 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 0 LQEDPNYS(1)PQR;LQEDPNYS(1)PQR ; 184.11 0.00010309 53825000 8132.2 8526.2 8369.6 7651.7 9638.7 9058.3 7737.3 4476.2 7632.8 6704.4 TRUE FALSE FALSE 7488.527789 9263.166736 8679.784739 7620.039293 9523.764798 7179.506472 7954.387814 5840.972774 6795.500936 6937.377401 1.079446505 1.335254838 1.251162253 1.098403453 1.372819186 1.034902104 1.146598686 0.8419569 0.979548977 1 12.76017466 -7.555930321 4.379999075 1.032659983 1.162313559 0.154485235 0.144978524 0.276249853 11.8191665 0.025347686 0.027154164 2.78E-08 7.555930321 0.129653576 LQEDPNYS(ph)PQRFPNAQR ddPTM_HeLa_Curcumin_4h_R1 2 LQEDPNYSPQRFPNAQR 17 1 P46379-3;P46379;P46379-2;P46379-5;A0A0G2JK23;A0A024RCR6;A0A0G2JL47;H0Y710;P46379-4;H0Y4L1 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 0 LQEDPNY(0.452)S(0.548)PQRFPNAQR;LQEDPNY(0.001)S(0.999)PQRFPNAQR ; 97.49 0.0011609 84445000 6117.6 4940.5 4749.6 5290.6 4977.6 7030.2 4942.4 3252.5 5715.4 5135.2 TRUE FALSE FALSE 5633.385505 5367.534806 4925.624354 5268.708899 4918.245371 5572.057273 5081.070442 4244.172277 5088.434919 5313.647818 1.060172917 1.010141242 0.926976067 0.991542737 0.925587382 1.048631273 0.956230186 0.798730443 0.957616141 1 12.3754869 -3.534618404 1.206469859 1.013186633 3.93E-08 0.545473308 0.048018802 3.665144313 1.236230566 0.007436382 7.138780468 0.000291999 3.534618404 -1.013186594 LQEEERER ddPTM_HeLa_Curcumin_4h_R1 5 LQEEERER 8 1 H0YN88;A0A075B716;H3BNC9;P08708 H0YN88 RPS17 40S ribosomal protein S17 0 0 ;;;; ;;;; 118.33 0.0047532 30931300 13013.3 13450 11009.24 10055.43 10477.45 16256.1 10816.26 8375.41 12689.9 12995.7 FALSE FALSE TRUE 11983.28357 14612.55807 11417.25212 10013.82329 10352.51325 12884.40162 11119.73515 10929.03395 11297.84972 13447.29961 0.891129366 1.086653714 0.849036792 0.744671688 0.769858154 0.958140444 0.826912129 0.812730754 0.840157507 1 13.71502887 -6.548628509 24.99209829 0.957999555 0.824277915 0.382089071 0.080020257 159.6441353 154946.1221 0.011932984 0.016876089 2.83E-07 6.548628509 -0.13372164 LQEEGGGS(ph)DEEETGSPSEDGMQSAR ddPTM_HeLa_Curcumin_4h_R1 1 LQEEGGGSDEEETGSPSEDGMQSAR 25 0 Q13610-2;Q13610 Q13610-2 PWP1 Periodic tryptophan protein 1 homolog 1 0 LQEEGGGS(0.998)DEEET(0.001)GSPSEDGMQSAR 51.976 0.0094879 14178000 3237.1 2021.9 2222.2 2217.4 2351.1 2994.3 2800.6 1822.6 2344.3 2410.2 TRUE FALSE FALSE 2980.880119 2196.664027 2304.556687 2208.224986 2323.064668 2373.248427 2879.177299 2378.30235 2087.136155 2493.954271 1.195242493 0.880795631 0.924057315 0.885431226 0.931478454 0.951600619 1.154462747 0.953627088 0.836878278 1 11.2842193 -7.254522971 24.98624918 1.092197844 0.95736114 0 0.116626822 535.6522382 1935100.988 0.017248025 0.02087209 5.57E-08 7.254522971 -0.134836704 LQEEMLQR ddPTM_HeLa_Curcumin_4h_R1 1 LQEEMLQR 8 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 0 120.87 0.0026316 9129100 2958.8 2792.4 2736.2 2955.3 3143.8 3840.3 3439.4 3123.1 2970.4 2828.1 FALSE FALSE TRUE 2724.607858 3033.762613 2837.605979 2943.071752 3106.312238 3043.778491 3535.900307 4075.318813 2644.554552 2926.376264 0.93105179 1.036696016 0.969665457 1.005705174 1.061487641 1.040118637 1.208286286 1.392616138 0.903696009 1 11.51489956 -2.97521753 0.628326708 0.971617026 3.290343685 0.921963602 0.038411675 2.297122753 0.183475149 0.006229853 5.572556677 0.001058723 2.97521753 2.318726659 LQEEQDGGS(ph)S(ph)DEDRAGPAPPGASDGVDIQDVK ddPTM_HeLa_Curcumin_4h_R1 1 LQEEQDGGSSDEDRAGPAPPGASDGVDIQDVK 32 1 H7C504;Q14147 H7C504 DHX34 Probable ATP-dependent RNA helicase DHX34 2 0 LQEEQDGGS(1)S(1)DEDRAGPAPPGASDGVDIQDVK 91.66 1.37E-08 11079000 2998.7 2468.4 2730.3 3164.2 2953.5 3332.2 2284.9 1837.9 3329 2822.3 TRUE FALSE FALSE 2761.349731 2681.757497 2831.48732 3151.107379 2918.281441 2641.064158 2349.008145 2398.267249 2963.817029 2920.374715 0.945546377 0.91829226 0.969563017 1.079007897 0.999283218 0.904357973 0.804351624 0.821219016 1.014875596 1 11.51193778 -4.960856837 3.20338585 0.978291072 0.812817124 0.737315108 0.041914815 0.103160535 2.164361557 0.006438895 0.021689159 1.09E-05 4.960856837 -0.165473948 LQEK(ac)EDLQELNDR ddPTM_HeLa_Curcumin_4h_R1 1 LQEKEDLQELNDR 13 1 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 1 LQEK(1)EDLQELNDR 178.22 1.39E-08 3440600 542.61 890.65 518.2 608.39 1293.4 1380.8 1173.8 702.8 1468.3 761.97 FALSE TRUE FALSE 499.6618459 967.6338173 537.4049479 605.8726434 1277.97705 1094.406515 1206.733669 917.0804847 1307.231164 788.4484008 0.633728023 1.227263339 0.68159812 0.768436644 1.620875949 1.388050904 1.530516985 1.163145849 1.657979346 1 9.622872532 -5.76850681 24.98210105 0.840580389 1.430452656 0.226068105 0.321849716 72.82217635 257414.2892 0.03032684 0.055828593 1.70E-06 5.76850681 0.589872267 LQEKEDLQELNDR ddPTM_HeLa_Curcumin_4h_R1 4 LQEKEDLQELNDR 13 1 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ;;; ;;; 119.62 0.0021923 257095000 20388.6 17378.6 17922 18495.3 19352 23501.5 18820.1 17320.5 22713 19901.6 FALSE FALSE TRUE 18774.8208 18880.72875 18586.20509 18418.77135 19121.24004 18627.02398 19348.14135 22601.44072 20221.44073 20593.17912 0.911700942 0.916843807 0.902541807 0.894411263 0.92852298 0.904523963 0.939541255 1.097520717 0.98194847 1 14.32987895 -4.26126759 23.64060961 0.94027693 1.097520813 0.675415078 0.034078778 3.951626046 542760.223 0.006148375 0.047625993 5.48E-05 4.26126759 0.157243883 VASPSQGQVGSS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 2 VASPSQGQVGSSSPK 15 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 0 VASPSQGQVGSS(0.794)S(0.205)PK;VASPSQGQVGS(0.019)S(0.628)S(0.353)PK ; 217.01 6.49E-42 2668400 3174.77 2766.52 2869.52 3211.56 3094.85 3319.58 2097.62 889.16 3927.2 2829.64 TRUE FALSE FALSE 2923.483604 3005.645661 2975.866935 3198.271416 3057.945935 2631.061689 2156.473572 1160.260791 3496.395985 2927.969779 0.998467821 1.026528922 1.016358487 1.092317085 1.044391222 0.898595917 0.736508138 0.396268021 1.194136637 1 11.51568495 -4.355641232 1.42608971 1.012166563 0.216023557 0.90343332 0.066488267 0.127558166 0.262270474 0.00550907 0.136920573 4.41E-05 4.355641232 -0.796143006 down LQELEDSIDNLS(ph)QNGEGR ddPTM_HeLa_Curcumin_4h_R1 1 LQELEDSIDNLSQNGEGR 18 0 C9JNL8;Q3MIT2 C9JNL8 PUS10 Putative tRNA pseudouridine synthase Pus10 1 0 LQELEDS(0.146)IDNLS(0.854)QNGEGR 105.38 0.0022881 0 447.15 347.88 412.77 462.67 657.71 714.77 406.36 691.6 725.62 452.5 TRUE FALSE FALSE 411.7576057 377.9491971 428.0676193 460.7555941 649.8672378 566.5186449 417.7613679 902.4656563 646.0213014 468.2243413 0.879402392 0.807196815 0.91423615 0.984048785 1.387939884 1.209929931 0.892224797 1.927421487 1.379726008 1 8.871056127 -2.34513406 1.403369065 0.969561767 199.9999897 0.553952528 0.219360311 133.9863026 1.577694848 0.026998049 84622.70648 0.004517165 2.34513406 199.0304279 LQELESCS(ph)GLGSTSDDTDVR ddPTM_HeLa_Curcumin_4h_R1 2 LQELESCSGLGSTSDDTDVR 20 0 Q14C86-4;Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;F8W9S7;Q14C86-3;H0Y4E7;H0Y7I9;C9IZ08;B4DGD8 Q14C86-4 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 0 LQELES(0.036)CS(0.946)GLGS(0.003)T(0.007)S(0.007)DDT(0.001)DVR;LQELES(0.002)CS(0.839)GLGS(0.136)T(0.019)S(0.004)DDTDVR ; 140.63 0.00011714 8717600 3047.5 2827.6 2863.2 3609 3461.4 4266.8 3689.3 3607.2 3073.4 2942 TRUE FALSE FALSE 2806.287159 3072.005144 2969.312711 3594.066914 3420.125066 3381.817583 3792.811829 4707.018674 2736.255709 3044.234281 0.921836791 1.009122446 0.975389026 1.180614428 1.1234763 1.110892681 1.245900111 1.546207762 0.898832171 1 11.57186368 -1 0.430331204 0.964810752 12.15702389 0.884306965 0.06211934 16.5438387 0.185614075 0.014504115 162.1030041 0.1 1 11.19221314 LQELESCSGLGST(ph)SDDTDVR ddPTM_HeLa_Curcumin_4h_R1 1 LQELESCSGLGSTSDDTDVR 20 0 Q14C86-4;Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;F8W9S7;Q14C86-3;H0Y4E7;H0Y7I9;C9IZ08;B4DGD8 Q14C86-4 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 0 LQELESCSGLGS(0.041)T(0.959)SDDTDVR 262.12 6.59E-55 37438000 1013.2 919.95 1069.4 1109.5 1127.6 1225.5 952.08 745.15 966.75 888.09 TRUE FALSE FALSE 933.0041509 999.4663788 1109.032905 1104.909183 1114.154106 971.3174858 978.7928024 972.3428048 860.6999437 918.9510614 1.015292533 1.087616545 1.206846535 1.202359113 1.212419413 1.056984998 1.065119617 1.058100747 0.936611295 1 9.843844223 -7.150475397 3.409802869 1.006869639 1.134426675 0.530360543 0.061624579 0.164800225 3.577284782 0.010725628 0.013230233 7.07E-08 7.150475397 0.127557036 SDSGGSSS(ph)EPFDR ddPTM_HeLa_Curcumin_4h_R1 1 SDSGGSSSEPFDR 13 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 0 SDS(0.007)GGS(0.003)S(0.218)S(0.771)EPFDR 208.08 3.61E-09 74525000 879.2 746.12 793.93 873.18 1048.3 1048.5 674.04 294.3 1147.5 913.13 TRUE FALSE FALSE 809.6103923 810.6112882 823.3537442 869.5670125 1035.799707 831.029281 692.9517483 384.0307152 1021.622121 944.8611995 0.856856428 0.857915733 0.871401794 0.920311907 1.096245361 0.879525248 0.733389993 0.406441407 1.081240421 1 9.883958602 -4.355388978 1.944540401 0.930169934 0.308497159 0.796955767 0.084203947 0.203053663 0.932516442 0.011601679 0.209971583 4.41E-05 4.355388978 -0.621672775 down LQEMEGTVK ddPTM_HeLa_Curcumin_4h_R1 1 LQEMEGTVK 9 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 111.06 0.0032766 7732800 1957.5 1962.3 1721.1 1898.1 1938.6 2206.4 1654.4 1548.2 2086.3 2085.6 FALSE FALSE TRUE 1802.561809 2131.912468 1784.88548 1890.246165 1915.483461 1748.767769 1700.818011 2020.239053 1857.43811 2158.074445 0.835263961 0.987877167 0.827073174 0.875894791 0.88758915 0.810337091 0.788118323 0.936130381 0.860692324 1 11.07552892 -10.64643366 0.390235285 1.167498995 0.856392343 0 0.072136074 4.533375993 0.405101643 0.690962495 0.01712461 2.26E-11 10.64643366 -0.311106652 LQEMEGTVK(ac)SK ddPTM_HeLa_Curcumin_4h_R1 2 LQEMEGTVKSK 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 1 ; LQEMEGTVK(1)SK;LQEMEGTVK(1)SK 174.42 3.50E-25 3473300 1776.73 1379.79 1225.15 1373.72 1485.73 1396.33 1458.66 1350.18 1556.24 1391.92 FALSE TRUE FALSE 1636.099946 1499.052899 1270.555137 1368.035911 1468.01364 1106.715418 1499.586074 1761.843667 1385.524366 1440.289116 1.135952447 1.040799991 0.882152842 0.949834235 1.019249277 0.768398098 1.041170177 1.223256946 0.961976557 1 10.49214272 -6.982183473 24.613998 1.065472218 0.973074536 0.024179499 0.118332201 336.245095 464529.7454 0.019108214 0.025110326 1.04E-07 6.982183473 -0.092397681 LQFHDVAGDIFHQQCK ddPTM_HeLa_Curcumin_4h_R1 2 LQFHDVAGDIFHQQCK 16 0 P11413;P11413-3;P11413-2 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 0 ; ; 171.26 3.14E-05 30307000 9334.2 6910.6 7500.8 7556.5 8274.6 10945.9 7624.5 6683.9 8926.8 8141.9 FALSE FALSE TRUE 8595.388221 7507.921471 7778.786246 7525.233205 8175.930799 8675.596954 7838.42295 8721.790341 7947.552374 8424.830419 1.020244657 0.891165887 0.923316656 0.893220733 0.970456424 1.029765173 0.930395339 1.035248178 0.943348647 1 13.04043193 -7.311075148 24.98902958 1.009559987 0.952609907 0.039488579 0.051326449 387.6874549 195179.6307 0.00805497 0.009211224 4.89E-08 7.311075148 -0.056950079 LQGQVS(ph)AK ddPTM_HeLa_Curcumin_4h_R1 1 LQGQVSAK 8 0 O95235-2;O95235 O95235-2 KIF20A Kinesin-like protein KIF20A 1 0 LQGQVS(1)AK 94.692 0.01816 40925000 4020 4293.7 3526.2 4365.2 5191.5 8333.3 7686.8 1588.9 5373.3 4457.9 TRUE FALSE FALSE 3701.812758 4664.828296 3656.884074 4347.137959 5129.594753 6604.879644 7902.47092 2073.348296 4783.862433 4612.811693 0.802506802 1.01127655 0.792766824 0.94240525 1.112032117 1.431855468 1.71315706 0.449476032 1.037081665 1 12.17143068 -5.641868869 3.431288174 0.905433527 1.25212237 0.12492258 0.308690396 0.270234962 6.211694362 0.041676737 0.087818551 2.28E-06 5.641868869 0.346688842 LQIEESSK(ac)PVR ddPTM_HeLa_Curcumin_4h_R1 1 LQIEESSKPVR 11 1 P13984 P13984 GTF2F2 General transcription factor IIF subunit 2 0 1 LQIEESSK(1)PVR 159.09 1.40E-07 2931900 984.67 683.22 885.46 786.2 877.12 975.8 760.93 1026.3 1100.1 897.44 FALSE TRUE FALSE 906.7323305 742.2744924 918.2759265 782.9469127 866.6609169 773.4080805 782.2796479 1339.214145 979.4217823 928.6259732 0.976423616 0.799325578 0.988854451 0.843124073 0.93327232 0.832852088 0.842405522 1.442145906 1.054699966 1 9.858953823 -4.254169931 24.97951507 0.944875927 1.442146141 0.76759669 0.085294714 330.6633462 1136207.755 0.012039815 0.165242483 5.57E-05 4.254169931 0.497270214 LQIGPPS(ph)PGEAQGPLLPSPAR ddPTM_HeLa_Curcumin_4h_R1 1 LQIGPPSPGEAQGPLLPSPAR 21 0 H7C1V4;Q9HCH0-2;Q9HCH0 H7C1V4 NCKAP5L Nck-associated protein 5-like 1 0 LQIGPPS(1)PGEAQGPLLPSPAR 132.76 2.91E-05 13552000 704.71 711.57 605.7 580.27 666.22 403.4 468.72 504.16 573.55 456.55 TRUE FALSE FALSE 648.9314599 773.0749401 628.1477748 577.8689965 658.2757616 319.7302927 481.8710217 657.8760631 510.633 472.4150785 1.373646798 1.636431552 1.329652256 1.223223015 1.393426653 0.676799508 1.020016176 1.392580578 1.08089903 1 8.883911203 -5.322076011 24.99946885 1.243522074 1.028811042 0.189975377 0.233169415 373.565415 154014.075 0.037274062 0.083347351 4.76E-06 5.322076011 -0.214711032 LQIVEMPLAHK ddPTM_HeLa_Curcumin_4h_R1 2 LQIVEMPLAHK 11 0 P50454;E9PR70;E9PPV6;E9PKH2 P50454 SERPINH1 Serpin H1 0 0 ; ; 84.479 0.009759 1523030 1816.28 1128.72 1955.02 1315.19 1400.5 2379.43 1079.55 963.69 1538.16 1467.66 FALSE FALSE TRUE 1672.519521 1226.281527 2027.474761 1309.748092 1383.799952 1885.909396 1109.839268 1257.514645 1369.427696 1518.661076 1.101311904 0.807475445 1.335040974 0.862436072 0.911197353 1.241823753 0.730801155 0.828041664 0.901733585 1 10.56858422 -4.737852246 24.99995212 1.039530107 0.779421193 0.257203214 0.160942799 194.6984629 206357.1925 0.019272546 0.072026166 1.83E-05 4.737852246 -0.260108914 LQKEEEIEFLYNENTVR ddPTM_HeLa_Curcumin_4h_R1 1 LQKEEEIEFLYNENTVR 17 1 J3KR24;A0A0A0MSX9;P41252 J3KR24 IARS "Isoleucine--tRNA ligase, cytoplasmic" 0 0 81.594 0.0074187 4191100 725.73 638.27 695.2 838.23 754.73 849.15 928.67 731.03 1085.6 850.06 FALSE FALSE TRUE 668.2877047 693.4392147 720.9647236 834.7616264 745.7303377 673.0267181 954.7259808 953.9176818 966.512396 879.5995217 0.759763606 0.788357881 0.819651109 0.949024648 0.847806666 0.765151301 1.085409845 1.084490905 1.098809597 1 9.78070301 -4.743686574 24.94610021 0.867688576 1.084950604 0.382044231 0.104257938 173.491025 243784.1105 0.014109091 0.052558463 1.80E-05 4.743686574 0.217262028 LQLEETDHQK ddPTM_HeLa_Curcumin_4h_R1 1 LQLEETDHQK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 87.184 0.0077954 2987700 2333.4 1945.4 2067.9 2175.5 2225.9 2550.7 2106.3 2058.5 2095.5 2213.9 FALSE FALSE TRUE 2148.708928 2113.551707 2144.538193 2166.498357 2199.357596 2021.656068 2165.397109 2686.127174 1865.628893 2290.83286 0.937959711 0.922612795 0.936139092 0.945725197 0.960068993 0.882498284 0.945244477 1.172554847 0.814388917 1 11.16165649 -4.259857243 24.95035789 0.95511976 1.172554921 0.619112691 0.053865569 51.50429233 812147.1285 0.005281185 0.044826413 5.50E-05 4.259857243 0.217435161 LQLEETMPS(ph)PYGR ddPTM_HeLa_Curcumin_4h_R1 1 LQLEETMPSPYGR 13 0 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 1 0 LQLEETMPS(0.99)PY(0.01)GR 107.93 0.0052389 11609000 2364.9 1993.3 2301 2141.7 2760.1 4084.8 4311.6 1572.3 2119.2 1530 TRUE FALSE FALSE 2177.71567 2165.59197 2386.277084 2132.838213 2727.18761 3237.566435 4432.571892 2051.687032 1886.729062 1583.167386 1.375543539 1.367885663 1.507280345 1.347196911 1.722614825 2.044993134 2.799812535 1.295938162 1.19174326 1 10.62859808 -5.969807536 0.463387336 1.105659315 2.231593036 0.429028229 0.372980785 0.857155143 0.310343121 0.105295704 0.41948449 1.07E-06 5.969807536 1.125933721 LQLERPVS(ph)PETQADLQR ddPTM_HeLa_Curcumin_4h_R1 2 LQLERPVSPETQADLQR 17 1 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 1 0 LQLERPVS(0.831)PET(0.169)QADLQR;LQLERPVS(0.788)PET(0.212)QADLQR ; 175.8 0.00015171 12810200 3545.2 3429.4 3298.9 3204.1 2536.8 2369.7 1681.6 1434.01 3586 3291.2 TRUE FALSE FALSE 3264.593679 3725.822055 3421.160136 3190.842283 2506.550317 1878.197508 1728.78117 1871.233048 3192.624772 3405.568955 0.958604486 1.094038061 1.004578143 0.936948371 0.736015142 0.551507702 0.507633583 0.549462681 0.937471775 1 11.73368013 -5.565695115 1.921621999 0.99208613 0.525287846 0.962865673 0.040310203 0.043085188 0.316962943 0.006161552 0.015607684 2.72E-06 5.565695115 -0.466798284 LQLERPVSPET(ph)QADLQR ddPTM_HeLa_Curcumin_4h_R1 1 LQLERPVSPETQADLQR 17 1 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 1 0 LQLERPVS(0.007)PET(0.993)QADLQR 157.74 0.0015576 5755300 1868 1757.3 1740.7 1436.8 1545.1 1627.1 1170.4 984.38 2174.9 2001.3 TRUE FALSE FALSE 1720.145829 1909.193182 1805.211873 1430.854902 1526.675692 1289.621119 1203.238274 1284.51293 1936.318911 2070.845026 0.830649231 0.921939188 0.87172717 0.690952188 0.737223536 0.622751149 0.581037334 0.620284432 0.935038058 1 11.01600388 -3.549028933 0.169856864 1.041538259 1.24E-11 0.85823743 0.053662256 6.574485849 0.152792837 0.109233956 1.52927092 0.000282469 3.549028933 -1.041538259 LQLGT(ph)PPPLLAAR ddPTM_HeLa_Curcumin_4h_R1 1 LQLGTPPPLLAAR 13 0 Q9P2N5 Q9P2N5 RBM27 RNA-binding protein 27 1 0 LQLGT(1)PPPLLAAR 103.11 0.016015 37609000 3927.8 3151.8 3280.4 3614.4 3092.5 5958.4 8419 4311.3 4030.3 2947.4 TRUE FALSE FALSE 3616.910485 3424.227548 3401.97451 3599.44457 3055.623957 4722.560675 8655.214481 5625.795523 3588.186173 3049.821931 1.18594153 1.122763107 1.115466603 1.180214666 1.001902415 1.548470954 2.837940928 1.844630818 1.176523172 1 11.5745093 -4.957565151 5.099728498 1.101415261 2.333245188 0.813772909 0.232702512 0.047185921 2.87663651 0.028664524 0.088226939 1.10E-05 4.957565151 1.231829927 LQLQGLDLS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 2 LQLQGLDLSSR 11 0 P49454 P49454 CENPF Centromere protein F 1 0 LQLQGLDLS(0.916)S(0.084)R;LQLQGLDLS(0.996)S(0.004)R ; 175.88 0.00020543 21979000 4315.2 3560.1 3705.4 3800.8 4419.2 5249.5 4772.5 1285.63 3836.7 2970.93 TRUE FALSE FALSE 3973.647367 3867.819181 3842.725384 3785.073297 4366.503926 4160.694526 4906.403505 1677.612669 3415.823609 3074.169596 1.292592111 1.258167144 1.250004355 1.231250644 1.420384852 1.353436886 1.596009378 0.545712465 1.111137009 1 11.58598104 -9.238960312 0.792144403 0.985175456 1.267379233 0.065346523 0.259415389 1.155965628 1.19737304 0.207436937 0.046923563 5.77E-10 9.238960312 0.282203776 AKS(ph)PTPESSTIASYVTLRK ddPTM_HeLa_Curcumin_4h_R1 2 AKSPTPESSTIASYVTLRK 19 2 A0JP02;B4DJX4;Q9HAU0-8;Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;Q9HAU0-5;H0YGJ6 A0JP02 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 0 AKS(0.926)PT(0.069)PES(0.004)S(0.001)TIASYVTLRK;AKS(0.917)PT(0.083)PESSTIASYVTLRK ; 106.31 0.00045582 129016000 5786.6 4205.4 4538.8 4755.9 4035.3 5602.1 2817.97 1283.26 6481.6 5222.8 TRUE FALSE FALSE 5328.584504 4568.896037 4707.011921 4736.221346 3987.181683 4440.161311 2897.034654 1674.520067 5770.584696 5404.291911 0.985991244 0.84541992 0.870976623 0.87638148 0.737780592 0.821599089 0.536061838 0.30985004 1.067778127 1 12.39988989 -4.355335431 0.522907372 0.98690874 2.61E-26 0.892788288 0.071227714 0.774406184 0.150787294 0.013749796 0.456641008 4.41E-05 4.355335431 -0.98690874 down LQLS(ph)PLTLCPLGR ddPTM_HeLa_Curcumin_4h_R1 1 LQLSPLTLCPLGR 13 0 Q5T1R4-2;Q5T1R4 Q5T1R4-2 HIVEP3 Transcription factor HIVEP3 1 0 LQLS(0.764)PLT(0.236)LCPLGR 106.55 0.0047875 7644400 1986.8 1540.8 1386 1847.1 1388.7 1511.6 1196.2 866.25 1729.1 2184.2 TRUE FALSE FALSE 1829.542684 1673.979886 1437.366379 1839.45719 1372.140659 1198.077121 1229.762153 1130.365637 1539.422056 2260.100787 0.80949606 0.740666034 0.635974461 0.813882814 0.60711481 0.530098979 0.54411828 0.500139482 0.681129826 1 11.14217139 -5.17671511 0.130932184 1.193203922 9.38E-19 0.416731939 0.113514009 4.381849838 0.138326555 0.314442521 1.064214591 6.66E-06 5.17671511 -1.193203922 LQLS(ph)PWESSVVNR ddPTM_HeLa_Curcumin_4h_R1 1 LQLSPWESSVVNR 13 0 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-3 MAP7 Ensconsin 1 0 LQLS(0.932)PWES(0.03)S(0.038)VVNR 187.08 3.34E-05 9927200 6139.7 4904 4958.7 5283.8 5339.1 8363.4 6617.8 4108.5 6117.4 4456.1 TRUE FALSE FALSE 5653.736266 5327.879908 5142.473784 5261.937036 5275.43472 6628.736565 6803.477657 5361.162737 5446.336525 4610.949143 1.226154549 1.155484423 1.115274453 1.141183056 1.144110368 1.437607824 1.475504814 1.162702639 1.181174712 1 12.17084804 -8.673062839 0.03670278 9.28E-10 2.224954346 0.252981042 0.119254786 123.034177 1.602385115 53.78838859 43.22958822 2.12E-09 8.673062839 2.224954345 LQMEAPHIIVGTPGR ddPTM_HeLa_Curcumin_4h_R1 5 LQMEAPHIIVGTPGR 15 0 P60842;J3KT12;P60842-2;J3KSZ0;J3KTB5;J3QS69;J3QL43;J3QR64;J3QKZ9;J3QLN6;J3KS25 P60842 EIF4A1 Eukaryotic initiation factor 4A-I 0 0 ;;;; ;;;; 115.58 0.00094305 66626500 17203 14840 15931.9 16763.3 16491.5 19946.6 14015 14142.2 17446.4 15677.8 FALSE FALSE TRUE 15841.3644 16122.70347 16522.35023 16693.93791 16294.84963 15809.45032 14408.22318 18454.09168 15532.57357 16222.60238 0.976499579 0.993841992 1.018477174 1.029054249 1.004453493 0.974532319 0.888157328 1.137554336 0.957464974 1 13.98571765 -4.232436641 24.58773361 0.988715023 1.137554624 0.597313782 0.037885563 4859.805872 4119932.094 0.0049299 0.711110095 5.86E-05 4.232436641 0.148839601 LQPGSVPK ddPTM_HeLa_Curcumin_4h_R1 1 LQPGSVPK 8 0 A0A087WV51;K7ES69;H3BQH0;A0A087X271;A0A087X1X5;H3BVI6;B4DDF4;B4DUT8;Q99439-2;Q99439 A0A087WV51 CNN2 Calponin;Calponin-2 0 0 96.19 0.016901 3818700 4035.5 3174.2 3550.8 3649.2 4126.5 4492.6 3542.8 3115.7 4323.2 3685.6 FALSE FALSE TRUE 3716.085917 3448.563704 3682.395772 3634.100577 4077.294183 3560.784118 3642.201433 4065.662587 3848.955776 3813.674326 0.974410922 0.904262769 0.965576884 0.952913193 1.0691249 0.933688567 0.955037353 1.066074929 1.009251301 1 11.89696593 -3.283648715 14.51786148 0.982188063 0.985238054 0 0.050990049 0 0 0.006224185 0 0.000520417 3.283648715 0.003049991 LQPLS(ph)PVPSDIEISR ddPTM_HeLa_Curcumin_4h_R1 1 LQPLSPVPSDIEISR 15 0 H0Y327;A0A087WVM4;B7ZM99;Q6UB35 H0Y327 MTHFD1L "Monofunctional C1-tetrahydrofolate synthase, mitochondrial" 1 0 LQPLS(0.982)PVPS(0.017)DIEIS(0.001)R 80.387 0.015512 3732900 652.38 877.58 715.67 1017.4 941.43 1429.9 985.12 640.89 1130.7 744.09 TRUE FALSE FALSE 600.7434346 953.4341048 742.1933598 1013.190268 930.2040621 1133.322622 1012.759816 836.2944107 1006.665039 769.9470721 0.78023991 1.238311229 0.96395374 1.315921971 1.208140268 1.471948739 1.315362903 1.086171298 1.307447064 1 9.588615465 -6.634812119 1.24390266 0.902921756 1.291605596 0.061206459 0.191072374 0.233144163 0.724445458 0.026814875 0.043032883 2.32E-07 6.634812119 0.38868384 LQPLSPVPS(ph)DIEISR ddPTM_HeLa_Curcumin_4h_R1 1 LQPLSPVPSDIEISR 15 0 H0Y327;A0A087WVM4;B7ZM99;Q6UB35 H0Y327 MTHFD1L "Monofunctional C1-tetrahydrofolate synthase, mitochondrial" 1 0 LQPLS(0.087)PVPS(0.896)DIEIS(0.017)R 90.853 0.0070971 6919500 1388.1 1453.7 1646 1683.9 1902.4 2304.9 1690.7 1181.7 1822.6 1541.7 TRUE FALSE FALSE 1278.23042 1579.35135 1707.002208 1676.932468 1879.715122 1826.837758 1738.136492 1541.99489 1622.66534 1595.27396 0.801260757 0.990018887 1.070037028 1.051187764 1.178302392 1.145156132 1.089553603 0.966601931 1.01717033 1 10.63958849 -6.899355917 3.280071948 0.905728269 1.090248842 0.390212944 0.078029676 0.160386592 3.447091755 0.014954031 0.019989231 1.26E-07 6.899355917 0.184520573 LQPQEIS(ph)PPPTANLDR ddPTM_HeLa_Curcumin_4h_R1 2 LQPQEISPPPTANLDR 16 0 Q05397-5;Q05397;Q05397-7;Q05397-2;E7ESA6;H0YBP1;H0YB16;H0YBZ1;E9PEI4;Q05397-6;B4DWJ1 Q05397-5 PTK2 Focal adhesion kinase 1 1 0 LQPQEIS(0.992)PPPT(0.008)ANLDR;LQPQEIS(0.999)PPPT(0.001)ANLDR ; 161.99 0.00024891 45550000 1886.03 2025.53 1662.81 2048.9 2314.8 2466.42 2083.6 3199.4 2087.8 2093 TRUE FALSE FALSE 1736.748735 2200.607788 1724.435201 2040.422195 2287.197522 1954.85669 2142.060208 4174.882332 1858.773563 2165.731594 0.801922427 1.016103655 0.796236803 0.942139922 1.056085402 0.902631099 0.989070028 1.92770071 0.858265894 1 11.08063874 -4.260123055 4.301452613 0.918148848 2.004619996 0.929717248 0.082542389 0.042451699 1.826879465 0.01284443 0.140880625 5.49E-05 4.260123055 1.086471148 LQPSSS(ph)PENSLDPFPPR ddPTM_HeLa_Curcumin_4h_R1 2 LQPSSSPENSLDPFPPR 17 0 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3;H3BUF6 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 0 LQPS(0.005)S(0.038)S(0.952)PENS(0.005)LDPFPPR;LQPS(0.001)S(0.002)S(0.997)PENSLDPFPPR ; 246.75 7.03E-31 286670000 10898 9338.4 8818.5 10295.7 10088 12811 11681.1 12127.1 11130 9885.8 TRUE FALSE FALSE 10035.4118 10145.56968 9145.321368 10253.09912 9967.707189 10153.85419 12008.84023 15824.59696 9909.066846 10229.33081 0.981042845 0.991811671 0.89402929 1.002323545 0.97442417 0.992621548 1.173961469 1.546982618 0.968691601 1 13.32042415 -4.28619628 1.882185463 0.982581407 1.708098856 0.970167659 0.030661988 0.088619058 0.333073018 0.004386709 0.110304073 5.17E-05 4.28619628 0.725517449 LQQELDDLLVDLDHQR ddPTM_HeLa_Curcumin_4h_R1 1 LQQELDDLLVDLDHQR 16 0 P35579 P35579 MYH9 Myosin-9 0 0 100.69 0.0021792 6195800 603.74 494.12 368.63 459.65 630.96 680.46 595.08 495.27 617.14 724.76 FALSE FALSE TRUE 555.9533419 536.829531 382.2917521 457.7480901 623.4362141 539.3249256 611.7763432 646.2755431 549.441286 749.9453561 0.741325134 0.715824862 0.509759476 0.610375258 0.831308853 0.719152297 0.815761226 0.861763511 0.732641761 1 9.550641669 -8.899057561 0.814900472 0.994722163 0.721587955 0.020426785 0.127322133 0.406022205 0.510627427 0.063639559 0.022260673 1.26E-09 8.899057561 -0.273134208 LQQELDDLTVDLDHQR ddPTM_HeLa_Curcumin_4h_R1 1 LQQELDDLTVDLDHQR 16 0 P35580;P35580-5;P35580-2;P35580-3;P35580-4 P35580 MYH10 Myosin-10 0 0 197.29 1.10E-07 1994600 2826.1 2702.2 2536.5 2577.5 2915.7 3002.2 2362.2 2400.9 2999.8 2944.1 FALSE FALSE TRUE 2602.411203 2935.766127 2630.504921 2566.834988 2880.932182 2379.509878 2428.476974 3132.923358 2670.729445 3046.407256 0.854255844 0.963681439 0.863477763 0.842577755 0.945681893 0.781087254 0.797160974 1.028399388 0.876681685 1 11.5728931 -9.467491991 0.722699924 1.018800143 0.877261653 0 0.081991916 1.024941223 0.743382913 0.093568347 0.013942045 3.41E-10 9.467491991 -0.14153849 LQQETAELEES(ph)VESGK ddPTM_HeLa_Curcumin_4h_R1 1 LQQETAELEESVESGK 16 0 P42566;P42566-2 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 0 LQQETAELEES(0.991)VES(0.009)GK 168.09 0.00016155 3758000 633.27 570.68 680.26 624.17 734.41 819.17 807.26 423.8 831.53 530.81 TRUE FALSE FALSE 583.1460113 620.0070363 705.471034 621.5873499 725.6526404 649.2649081 829.909543 553.0146691 740.3132394 549.255608 1.061702426 1.128813302 1.284412983 1.131690493 1.321156543 1.182081527 1.510971451 1.006843919 1.347848303 1 9.101333885 -7.07647728 0.983892599 1.017394698 1.25925656 0 0.163051823 0.324889992 0.618871493 0.023587386 0.030896658 8.39E-08 7.07647728 0.241861861 LQQGAGLES(ph)PQGQPEPGAAS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 3 LQQGAGLESPQGQPEPGAASPQR 23 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 2 0 LQQGAGLES(1)PQGQPEPGAAS(1)PQR;LQQGAGLES(1)PQGQPEPGAAS(1)PQR;LQQGAGLES(1)PQGQPEPGAAS(1)PQR ;; 150.45 5.89E-06 78633700 5569.66 5360.49 4996.42 4933.35 5987.4 6450.7 4255.1 2506.25 6201.6 4020.5 TRUE FALSE FALSE 5128.815534 5823.82687 5181.59172 4912.937105 5916.004165 5112.752106 4374.486654 3270.394088 5521.299996 4160.212076 1.2328255 1.399887016 1.245511437 1.180934293 1.422043891 1.228964296 1.051505686 0.786112349 1.327167917 1 12.02244136 -4.353967866 2.866876135 1.175808144 0.755355419 0.482309669 0.132976707 0.283507626 3.547905558 0.022130465 0.245353979 4.43E-05 4.353967866 -0.420452725 LQQGAGLESPQGQPEPGAAS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 2 LQQGAGLESPQGQPEPGAASPQR 23 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 0 LQQGAGLESPQGQPEPGAAS(1)PQR;LQQGAGLES(0.002)PQGQPEPGAAS(0.998)PQR ; 115.66 2.09E-06 130261000 4152.9 3756.7 4011.4 4044.1 4256.9 4596.1 4028.7 3339.1 3728.2 3619.4 TRUE FALSE FALSE 3824.193583 4081.412408 4160.066013 4027.366586 4206.139248 3642.817051 4141.734479 4357.176219 3319.225787 3745.173881 1.021099074 1.08977915 1.110780473 1.075348359 1.123082501 0.972669672 1.105885764 1.163410928 0.886267472 1 11.87081699 -7.321158587 3.608315726 1.008987059 1.089159858 0.424231934 0.060292157 0.179908251 4.595751702 0.007945094 0.00916345 4.77E-08 7.321158587 0.080172799 LQQGAGLESPQGQPEPGAAS(ph)PQRQQDLHLESPQR ddPTM_HeLa_Curcumin_4h_R1 1 LQQGAGLESPQGQPEPGAASPQRQQDLHLESPQR 34 1 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 0 LQQGAGLES(0.027)PQGQPEPGAAS(0.958)PQRQQDLHLES(0.015)PQR 48.106 0.004998 40273000 1639.4 1283.9 1183.7 1287.1 1493 2234.4 1366.3 1610.7 1994 1331.7 TRUE FALSE FALSE 1509.63976 1394.874595 1227.568963 1281.774321 1475.19695 1770.960253 1404.634701 2101.795015 1775.263189 1377.976476 1.095548282 1.012262995 0.890848998 0.930185924 1.070553073 1.285189032 1.019345922 1.525276412 1.28831168 1 10.42833554 -1.190772808 0.936637538 1.030272966 199.9999985 0.506002575 0.130908604 359.8882032 0.951196514 0.016025527 152917.2564 0.064450634 1.190772808 198.9697255 S(ph)PGAPGPLTLK ddPTM_HeLa_Curcumin_4h_R1 1 SPGAPGPLTLK 11 0 Q15942;Q15942-2;H0Y2Y8;C9JJK5 Q15942 ZYX Zyxin 1 0 S(1)PGAPGPLTLK 115.92 0.0047304 158990000 5554.8 4816 4639.1 5166.8 5140.9 6604.3 5418.3 10461 5711.9 4247.7 TRUE FALSE FALSE 5115.131719 5232.27358 4811.029127 5145.421151 5079.598125 5234.493734 5570.322915 13650.51074 5085.31886 4395.307259 1.163771135 1.19042271 1.094583119 1.170662447 1.155686696 1.19092783 1.267334133 3.105701135 1.156988252 1 12.10174831 -4.254480066 3.81985473 1.108816427 3.32020233 0.989239671 0.061102286 0.024578937 0.687602009 0.01174057 0.15323963 5.57E-05 4.254480066 2.211385904 up LQQQHSEQPPLQPS(ph)PVMTR ddPTM_HeLa_Curcumin_4h_R1 1 LQQQHSEQPPLQPSPVMTR 19 0 A0A0A0MSK5;J3KN66;Q5JTV8;Q5JTV8-3;H0YDU3;Q5JTV8-2 A0A0A0MSK5 TOR1AIP1 Torsin-1A-interacting protein 1 1 0 LQQQHSEQPPLQPS(0.5)PVMT(0.5)R 58.864 0.014883 10638000 775.37 1078.2 1143.2 1317.9 887.18 903.29 415.97 251.75 1532.5 1047.4 TRUE FALSE FALSE 713.9986463 1171.394804 1185.567998 1312.446879 876.6009579 715.9374718 427.6409987 328.5074161 1364.388584 1083.797072 0.658793666 1.080824846 1.093902196 1.210971051 0.808823885 0.660582585 0.394576632 0.303107865 1.258896725 1 10.08187894 -4.92470803 1.971873475 0.901042805 0.312763386 0.636338127 0.191964457 0.20014611 1.478431381 0.028970967 0.132193237 1.19E-05 4.92470803 -0.588279419 EGLTS(ph)IEEVTK ddPTM_HeLa_Curcumin_4h_R1 1 EGLTSIEEVTK 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 EGLT(0.03)S(0.967)IEEVT(0.003)K 122.46 0.003879 5240800 2352.6 1931.4 2262.7 1999.3 2193.8 2567.7 3287.7 9711.9 2543 1968.3 TRUE FALSE FALSE 2166.389228 2098.34161 2346.557652 1991.027426 2167.640368 2035.130076 3379.944014 12673.0136 2264.039262 2036.698278 1.063677055 1.030266305 1.152138084 0.977576034 1.064291354 0.999230027 1.659521221 6.222332358 1.111622318 1 10.99201656 -4.25437488 3.304479896 1.03975018 6.974199548 0.998657748 0.056530264 0.009254039 0.160787906 0.009128788 0.140499289 5.57E-05 4.25437488 5.934449368 up LQS(ph)IGTENTEENRR ddPTM_HeLa_Curcumin_4h_R1 1 LQSIGTENTEENRR 14 1 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 0 LQS(0.807)IGT(0.192)ENT(0.001)EENRR 77.027 0.010589 16826000 511.46 480.96 545.02 683.85 654.21 687.3 534.79 647.38 483.52 481.89 TRUE FALSE FALSE 470.9774013 522.5320393 565.2189206 681.0204099 646.408973 544.7462325 549.7947681 844.7631818 430.4790657 498.6356416 0.944532163 1.047923565 1.133530926 1.365767613 1.296355333 1.092473516 1.102598214 1.694149217 0.86331387 1 8.961842198 -6.635840674 2.261382596 0.975363462 1.285320882 0.500604939 0.162238106 0.198530725 2.068489601 0.024884882 0.036997348 2.31E-07 6.635840674 0.30995742 LQS(ph)PLPGESAAK ddPTM_HeLa_Curcumin_4h_R1 1 LQSPLPGESAAK 12 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 0 LQS(0.714)PLPGES(0.286)AAK 128.35 0.0026835 7986700 3121.1 3016.8 2708.9 2954.1 2973.4 3272.6 2932 1696.3 3024.9 2882.7 TRUE FALSE FALSE 2874.061642 3277.558749 2809.294217 2941.876717 2937.944147 2593.82587 3014.264029 2213.494061 2693.076038 2982.87361 0.963521093 1.098792365 0.941807996 0.986255907 0.984937524 0.869572838 1.01052355 0.742067667 0.902846178 1 11.54248713 -3.707606136 1.69931965 0.983492225 5.78E-27 0.540096962 0.061789102 2.82679421 2.080432983 0.007492576 7.273372044 0.000196062 3.707606136 -0.983492225 LQSFDS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 LQSFDSPER 9 0 E9PGM9;P78332;P78332-2 E9PGM9 RBM6 RNA-binding protein 6 1 0 LQS(0.001)FDS(0.999)PER 118.87 0.006529 209130000 3943.3 2868.8 3552.8 3445.2 3950.6 4276.9 3322.9 1600.6 3485.6 3106.8 TRUE FALSE FALSE 3631.183644 3116.766289 3684.469893 3430.944675 3903.491675 3389.822729 3416.131631 2088.615572 3103.238401 3214.761069 1.129534533 0.969517243 1.146110026 1.067247177 1.214240061 1.054455574 1.062639356 0.649695429 0.965309189 1 11.6504958 -4.261016857 6.071638802 1.072471833 0.638684424 0.735635918 0.075143243 0.048240006 8.77219493 0.009954878 0.085753325 5.48E-05 4.261016857 -0.43378741 SNTEPQS(ph)PPIASPK ddPTM_HeLa_Curcumin_4h_R1 1 SNTEPQSPPIASPK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 0 S(0.001)NTEPQS(0.999)PPIASPK 172.42 0.00019715 11109000 5203 4233.9 5049.6 5173 4758.5 6612.1 7566.4 22387 5870.4 5480.7 TRUE FALSE FALSE 4791.17706 4599.85945 5236.742618 5151.595497 4701.757995 5240.675926 7778.69282 29212.69324 5226.431807 5671.153917 0.844832838 0.811097621 0.92339984 0.908385766 0.829065489 0.924093404 1.371624353 5.151102169 0.921581725 1 12.4694266 -4.254285846 3.429439562 0.911511378 5.723512636 0.997985161 0.057002631 0.013357829 0.261196691 0.011431924 0.168525818 5.57E-05 4.254285846 4.812001258 up LQSIGTENTEENR ddPTM_HeLa_Curcumin_4h_R1 2 LQSIGTENTEENR 13 0 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 ; ; 286.19 4.61E-95 7807600 1066.39 1018.81 1022.9 1034.16 1093.1 881.71 1254.09 1194.92 955.97 836.35 FALSE FALSE TRUE 981.9841063 1106.871397 1060.809574 1029.88092 1080.065496 698.8334071 1289.27639 1559.245607 851.1024827 865.4131002 1.13469984 1.279009292 1.225784049 1.190045447 1.248034605 0.807514246 1.489781458 1.801735618 0.983463831 1 9.75724515 -4.554147172 5.497793286 1.100542289 1.735132116 0.721957569 0.139311071 0.058416589 4.77575986 0.01953881 0.081310717 2.79E-05 4.554147172 0.634589827 LQSIGTENTEENRR ddPTM_HeLa_Curcumin_4h_R1 6 LQSIGTENTEENRR 14 1 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 ;;;;; ;;;;; 115.06 0.0019811 311212000 11603 9811.5 9989.7 10526.9 10384.7 12383.7 9821.5 10098.6 11542.6 11021.4 FALSE FALSE TRUE 10684.61031 10659.56234 10359.92707 10483.34248 10260.86923 9815.181027 10097.06486 13177.61665 10276.40566 11404.39283 0.936885502 0.934689159 0.908415487 0.91923723 0.899729551 0.860649153 0.88536628 1.155486035 0.90109187 1 13.47730202 -8.866299164 0.739274235 0.999899997 0.929890186 0 0.082623646 1.233071991 1.262292098 0.047692173 0.015869845 1.36E-09 8.866299164 -0.070009811 LQSS(ph)QEPEAPPPR ddPTM_HeLa_Curcumin_4h_R1 2 LQSSQEPEAPPPR 13 0 Q5H909;Q9UNF1-2;Q9UNF1;Q5H907 Q5H909 MAGED2 Melanoma-associated antigen D2 1 0 LQS(0.328)S(0.672)QEPEAPPPR;LQS(0.118)S(0.882)QEPEAPPPR ; 115.83 0.0028918 78726000 3800.8 3557.5 3102.3 4401.2 4150.9 4912.5 4342.8 3170.6 4087.1 3622.3 TRUE FALSE FALSE 3499.962669 3864.994448 3217.273967 4382.989001 4101.403229 3893.592125 4464.64728 4137.301344 3638.755355 3748.174655 0.933777903 1.031167116 0.858357537 1.169366266 1.094240158 1.038796877 1.191152412 1.103817651 0.97080731 1 11.87197247 -6.247974993 24.9997214 0.966085074 1.117572754 0.660007221 0.057526489 379.9420784 705449.6023 0.008409134 0.013892203 5.65E-07 6.247974993 0.15148768 LQSS(ph)QEPEAPPPRDVALLQGR ddPTM_HeLa_Curcumin_4h_R1 2 LQSSQEPEAPPPRDVALLQGR 21 1 Q5H909;Q9UNF1-2;Q9UNF1;Q5H907 Q5H909 MAGED2 Melanoma-associated antigen D2 1 0 LQS(0.312)S(0.688)QEPEAPPPRDVALLQGR;LQS(0.218)S(0.782)QEPEAPPPRDVALLQGR ; 65.881 0.0045236 11503000 2194.24 1515.79 1864.78 1796.24 1553.99 2265.69 1459.56 1613.49 2305.24 1951.63 TRUE FALSE FALSE 2020.563589 1646.808133 1933.890387 1788.807635 1535.459684 1795.760354 1500.511325 2105.435673 2052.360939 2019.448997 1.000551928 0.815473991 0.957632696 0.885789954 0.760335956 0.889232834 0.743030068 1.042579276 1.016297486 1 10.97974599 -7.275804463 23.83882707 1.000260643 0.86608638 0.353548945 0.083426266 311.8355446 517489.3124 0.012918778 0.014814964 5.30E-08 7.275804463 -0.134174263 SRT(ph)PSASNDDQQE ddPTM_HeLa_Curcumin_4h_R1 1 SRTPSASNDDQQE 13 1 O43765 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 0 S(0.17)RT(0.822)PS(0.003)AS(0.005)NDDQQE 131.35 0.01499 63492000 4091.4 3740.9 3408.7 3367.1 3130.2 3383.7 2419.3 653.21 4072.3 3201.6 TRUE FALSE FALSE 3767.561373 4064.246727 3535.029421 3353.167832 3092.874409 2681.882478 2487.179047 852.370722 3625.578878 3312.855362 1.137255015 1.226810797 1.067064219 1.012168497 0.933597779 0.809538053 0.750765963 0.257291861 1.094396973 1 11.6938595 -4.353060724 0.87629454 1.076584788 3.78E-14 0.90844755 0.079347075 0.475328104 0.29361552 0.014198209 0.474477302 4.44E-05 4.353060724 -1.076584788 down LQTEAQEDDWYDCHR ddPTM_HeLa_Curcumin_4h_R1 2 LQTEAQEDDWYDCHR 15 0 Q9UHI6;E9PJ60 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 0 0 ; ; 176.25 6.71E-05 19019600 3453.7 3236.8 3284.2 3366.3 2955.8 3690.4 2311.22 1287.18 3657.1 3678.8 FALSE FALSE TRUE 3180.336001 3516.574569 3405.915341 3352.371143 2920.554015 2924.969441 2376.066613 1679.635257 3255.92528 3806.638026 0.835471085 0.92380062 0.894730552 0.880664544 0.767226617 0.768386545 0.624190321 0.441238501 0.855328313 1 11.89430167 -3.969632277 0.524702883 0.928225237 4.24E-20 0.903808267 0.047727622 1.307040258 0.195638723 0.012083923 0.793631612 0.000107243 3.969632277 -0.928225237 down LQTPNTFPK ddPTM_HeLa_Curcumin_4h_R1 1 LQTPNTFPK 9 0 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 0 92.051 0.018328 1788100 1536 1133.6 1390.5 1164.5 1626.4 1815.3 1445.5 1240.1 1380.5 1338 FALSE FALSE TRUE 1414.423979 1231.583333 1442.033153 1159.681608 1607.006242 1438.786317 1486.05684 1618.200781 1229.062604 1384.4954 1.021616958 0.889553936 1.041558645 0.837620412 1.160716202 1.039213505 1.073356285 1.168801847 0.887733252 1 10.43514455 -5.714549847 24.9999851 0.992216444 1.102773786 0.457960114 0.078318851 98.37109932 52447.75016 0.009721171 0.019442298 1.93E-06 5.714549847 0.110557342 LQTSSVLVSGLR ddPTM_HeLa_Curcumin_4h_R1 1 LQTSSVLVSGLR 12 0 P22314;P22314-2;Q5JRR9;Q5JRS0;Q5JRS2;Q5JRS1;Q5JRS3 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 0 134.98 0.00029512 4033900 485.04 562.17 471.71 368.5 745.19 744.28 559.15 533.24 605.84 392.96 FALSE FALSE TRUE 446.6485722 610.7614698 489.1919876 366.9752446 736.3040959 589.9079382 574.8382441 695.8224213 539.3808677 406.6153308 1.098454826 1.502062081 1.203082989 0.902512072 1.810812432 1.450776431 1.413715127 1.711254763 1.32651385 1 8.6675208 -4.752031465 0.236177241 0.950492514 2.082431225 0.262342408 0.241049621 5.467813539 0.310783821 0.190823629 1.80634203 1.77E-05 4.752031465 1.131938711 SQSLPHS(ph)ATVTLGGTSDPSTLSSSALSER ddPTM_HeLa_Curcumin_4h_R1 1 SQSLPHSATVTLGGTSDPSTLSSSALSER 29 0 F8WDP1;A0A0A0MRY0;Q8WUA7-3;Q8WUA7-4;Q8WUA7 F8WDP1 TBC1D22A TBC1 domain family member 22A 1 0 S(0.014)QS(0.116)LPHS(0.411)AT(0.411)VT(0.046)LGGT(0.001)S(0.001)DPSTLSSSALSER 72.578 7.22E-05 11654000 1283.8 952.23 1149.2 1099.3 1233.9 1923.9 1735.1 6042.1 1359.4 1299.4 TRUE FALSE FALSE 1182.185875 1034.536518 1191.790363 1094.751388 1219.186548 1524.861453 1783.782236 7884.308476 1210.277221 1344.554053 0.879240126 0.769427243 0.886383377 0.814211511 0.906759044 1.134102009 1.326672016 5.86388361 0.900132812 1 10.39291204 -4.254254455 3.793964954 0.929492507 6.403131215 0.995672273 0.097371672 0.014042843 0.383671527 0.0163763 0.215743188 5.57E-05 4.254254455 5.473638708 up LQVVDQPLPVR ddPTM_HeLa_Curcumin_4h_R1 1 LQVVDQPLPVR 11 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 0 133.23 0.00061975 1268800 1371.5 1205.7 1505.6 1440.6 1582.8 2029.8 1324.1 1415.7 1686.9 1472.4 FALSE FALSE TRUE 1262.944328 1309.915336 1561.39886 1434.639179 1563.926144 1608.796599 1361.250682 1847.340413 1501.85129 1523.56579 0.828939804 0.859769459 1.024831924 0.941632575 1.026490719 1.055941666 0.89346367 1.212511087 0.98574758 1 10.57323608 -5.908595812 1.079151977 0.916078441 1.047921135 0.248169604 0.091180545 0.56130581 1.284679247 0.016329823 0.042961651 1.23E-06 5.908595812 0.131842694 LQWDGSSDLS(ph)PSDSGSSK ddPTM_HeLa_Curcumin_4h_R1 1 LQWDGSSDLSPSDSGSSK 18 0 K7EKG9;Q14CW9;K7EJK2;K7ENU1;Q14CW9-2 K7EKG9 ATXN7L3 Ataxin-7-like protein 3 1 0 LQWDGSSDLS(0.915)PS(0.039)DS(0.039)GS(0.006)S(0.001)K 181.6 6.06E-07 15317000 3893.1 3210.8 3343.3 3423.4 3078.3 4365.5 3255.3 2613.1 4045.3 2963.4 TRUE FALSE FALSE 3584.957027 3488.327245 3467.205639 3409.234878 3041.593283 3460.046091 3346.634957 3409.822161 3601.540711 3066.377929 1.169117803 1.137605124 1.130716995 1.111811706 0.991917289 1.12838214 1.091396766 1.11200323 1.174526035 1 11.5823198 -9.518844244 1.291944979 1.00040532 1.114252302 0 0.069311024 0.336292777 1.010555184 0.033221667 0.008105683 3.03E-10 9.518844244 0.113846982 LRAETEQGEQQR ddPTM_HeLa_Curcumin_4h_R1 4 LRAETEQGEQQR 12 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ;;; ;;; 199.82 4.80E-15 20175200 3321.16 2724.94 2773.44 2671.39 2486.57 3393.5 2550.81 2415.59 3520.61 2783.47 FALSE FALSE TRUE 3058.286682 2960.471672 2876.226126 2660.336496 2456.919277 2689.649847 2622.378863 3152.092271 3134.407891 2880.195375 1.061833064 1.027871823 0.998621882 0.92366529 0.853039102 0.933842846 0.91048645 1.09440224 1.088262247 1 11.49195096 -6.440288021 3.498919979 1.029577641 0.936092158 0.362529633 0.061820481 0.21015943 4.912838547 0.009357571 0.014447621 3.63E-07 6.440288021 -0.093485484 LRDADPILR ddPTM_HeLa_Curcumin_4h_R1 1 LRDADPILR 9 1 P31327-2;P31327;P31327-3 P31327-2 CPS1 "Carbamoyl-phosphate synthase [ammonia], mitochondrial" 0 0 100.25 0.011198 3523300 1855.6 1565.3 1642.5 2081.9 2097.1 2911 1817.7 1425.7 2069.9 1446.7 FALSE FALSE TRUE 1708.727302 1700.597557 1703.372495 2073.285649 2072.093452 2307.225786 1868.69977 1860.389367 1842.837149 1496.972717 1.141455206 1.136024416 1.137878116 1.384985595 1.384189189 1.541261079 1.24831919 1.242767717 1.231042575 1 10.54783221 -6.393779172 2.569347611 1.073765009 1.367338442 0.544324842 0.100362363 0.130940439 1.684555035 0.015695172 0.025178517 4.04E-07 6.393779172 0.293573433 SQETPATK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 SQETPATKK 9 1 M0QXK2;M0R221;M0R2B8;M0R268;P09012;M0QZG7 M0QXK2 SNRPA U1 small nuclear ribonucleoprotein A 0 1 ; SQETPATK(1)K;SQETPATK(1)K 154.85 1.94E-08 13662400 7806.3 7258.7 5826.9 5623.4 6097.6 9596.5 7365.3 9893.4 7647.2 6181.9 FALSE TRUE FALSE 7188.423118 7886.109684 6042.85004 5600.131861 6024.890102 7606.077725 7571.950495 12909.85212 6808.321292 6396.720565 1.123766944 1.232836358 0.944679384 0.875469204 0.941871705 1.189058932 1.183723819 2.018198542 1.064345585 1 12.64311675 -4.043240748 1.774076285 1.047240322 2.841621204 0.880815758 0.106637321 0.451897686 0.875791357 0.016352937 1.628314949 9.05E-05 4.043240748 1.794380883 up LRDLEDSLAR ddPTM_HeLa_Curcumin_4h_R1 4 LRDLEDSLAR 10 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ;;; ;;; 177.78 6.13E-16 201260400 23727.2 18372.3 19567 20013.8 17951.7 27214.5 20728.5 19741.2 24013.6 21302 FALSE FALSE TRUE 21849.16708 19960.31975 20292.17023 19930.9882 17737.6377 21569.90593 21310.08592 25760.201 21379.36816 22042.24291 0.991240645 0.905548488 0.920603693 0.904217791 0.804711107 0.978571283 0.966783916 1.168674218 0.969927073 1 14.42798341 -4.260995659 6.442889704 0.963143701 1.17295875 0.538797 0.060109973 0.089678487 21.70398932 0.009672586 0.081488844 5.48E-05 4.260995659 0.20981505 LREDENAEPVGTTYQK ddPTM_HeLa_Curcumin_4h_R1 2 LREDENAEPVGTTYQK 16 1 Q16643-3;Q16643;Q16643-2;D6R9W4 Q16643-3 DBN1 Drebrin 0 0 ; ; 205.28 1.25E-18 6901200 3958.2 3341.9 3841.7 3583.2 4169.9 5086.2 4004 3646.1 4221.1 3750.8 FALSE FALSE TRUE 3644.904293 3630.758945 3984.076782 3568.373668 4120.176666 4031.264787 4116.341464 4757.779105 3758.055891 3881.140021 0.939132387 0.93548775 1.0265223 0.919413793 1.061589287 1.038680585 1.060601123 1.225871543 0.968286604 1 11.92226477 -1 0.597594927 0.969524492 16.64599284 0.794323562 0.038739597 50.1868442 0.360619078 0.007014917 1029.751769 0.1 1 15.67646835 LREEWQR ddPTM_HeLa_Curcumin_4h_R1 1 LREEWQR 7 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424;H0YDG6;H0YDQ3;U3KQE6 Q8WWI1-3 LMO7 LIM domain only protein 7 0 0 116.88 0.011781 6458700 2158.8 1381.1 1505 1592 1974.3 2692.8 1786.8 2061.6 2262 1786.8 FALSE FALSE TRUE 1987.928702 1500.47613 1560.776624 1585.412726 1950.757762 2134.282926 1836.932799 2690.17235 2013.864259 1848.891167 1.075200497 0.811554599 0.844169009 0.857493807 1.055096047 1.154358333 0.993532141 1.45501931 1.089228125 1 10.85244459 -1.831413234 1.219283187 0.997325076 199.9999999 0.608684572 0.111270933 382.1428197 1.651013864 0.017562248 211460.3086 0.014743031 1.831413234 199.0026748 LREQLQLLEEQHR ddPTM_HeLa_Curcumin_4h_R1 2 LREQLQLLEEQHR 13 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 129.37 0.00078257 37722000 7305.3 5344.3 6103.2 6491.4 6114.5 8255.6 6629.7 5656.7 7764.6 7449.4 FALSE FALSE TRUE 6727.077796 5806.237478 6329.389961 6464.540307 6041.588581 6543.2955 6815.711539 7381.40179 6912.842806 7708.266096 0.872709597 0.753248189 0.821117211 0.838650382 0.78378049 0.848867361 0.884208129 0.957595612 0.896809052 1 12.91219066 -8.611850054 0.864497449 0.989833736 0.84127702 0.271283929 0.060482447 0.316432625 0.479446954 0.024586119 0.011860218 2.44E-09 8.611850054 -0.148556716 LREQYGLGPYEAVT(ph)PLTK ddPTM_HeLa_Curcumin_4h_R1 1 LREQYGLGPYEAVTPLTK 18 1 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 LREQYGLGPYEAVT(0.718)PLT(0.282)K 94.564 0.0017678 28469000 1079.2 900.72 735.26 844.2 892.72 1711.3 1704.3 1175 1164.8 1119.9 TRUE FALSE FALSE 993.7801812 978.5742233 762.5093824 840.7069241 882.0748971 1356.35709 1752.118071 1533.252091 1037.024354 1158.816442 0.857582051 0.844460078 0.658007045 0.72548757 0.761186039 1.170467592 1.511989309 1.323119034 0.894899586 1 10.17843634 -5.023404718 3.99324287 0.878430772 1.411284042 0.823254803 0.110758669 0.080738027 2.878398565 0.019328766 0.057254154 9.48E-06 5.023404718 0.53285327 LRESTPGDSPS(ph)TVNK ddPTM_HeLa_Curcumin_4h_R1 1 LRESTPGDSPSTVNK 15 1 Q5T6F2 Q5T6F2 UBAP2 Ubiquitin-associated protein 2 1 0 LRESTPGDS(0.191)PS(0.617)T(0.191)VNK 121.95 0.011236 20146000 5411.5 4444.1 4852.9 5016.6 4907.6 8635.5 7169.7 3700.2 5932.4 4186.2 TRUE FALSE FALSE 4983.174065 4828.228201 5032.752743 4995.842638 4849.080075 6844.399958 7370.862486 4828.373946 5281.630562 4331.670138 1.150404787 1.114634321 1.161850414 1.153329427 1.119448139 1.580083372 1.701621372 1.114667967 1.219305809 1 12.08070767 -5.286504064 10.7941889 1.09196529 1.489052161 0.48940127 0.152197742 0.352261648 151.0078927 0.020420282 0.046121623 5.17E-06 5.286504064 0.397086871 LRESTPGDSPST(ph)VNK ddPTM_HeLa_Curcumin_4h_R1 1 LRESTPGDSPSTVNK 15 1 Q5T6F2 Q5T6F2 UBAP2 Ubiquitin-associated protein 2 1 0 LREST(0.026)PGDS(0.22)PS(0.172)T(0.582)VNK 182.7 0.00039759 73002000 1843.1 1682.6 1663.4 1787.9 1599.7 2764.5 2567.5 1833.2 2090.5 1633.4 TRUE FALSE FALSE 1697.21669 1828.036446 1725.047067 1780.502144 1580.624622 2191.111538 2639.53714 2392.134241 1861.17738 1690.160528 1.004174847 1.081575635 1.020640962 1.0534515 0.93519201 1.296392562 1.561707954 1.41532961 1.101183792 1 10.72294456 -5.059847523 3.602316761 1.010160973 1.483967015 0.910492095 0.058647396 0.034498682 0.884075406 0.006727506 0.019777147 8.71E-06 5.059847523 0.473806041 SFSLASSSNS(ph)PISQR ddPTM_HeLa_Curcumin_4h_R1 4 SFSLASSSNSPISQR 15 0 Q9BXB4 Q9BXB4 OSBPL11 Oxysterol-binding protein-related protein 11 1 0 SFSLASSSNS(0.996)PIS(0.004)QR;SFS(0.017)LAS(0.002)S(0.35)S(0.063)NS(0.568)PISQR;SFSLAS(0.001)S(0.001)S(0.01)NS(0.908)PIS(0.081)QR;SFSLASS(0.001)S(0.008)NS(0.99)PIS(0.001)QR ;;; 264.85 1.97E-50 351890000 9980.43 7841.61 8983.01 8836.47 8359.91 8267.04 5933.38 1578.21 9318.37 7980.44 TRUE FALSE FALSE 9190.468434 8519.403827 9315.928253 8799.907028 8260.223533 6552.362715 6099.854674 2059.398964 8296.168124 8257.759696 1.112949368 1.031684639 1.128142329 1.065653077 1.000298366 0.793479461 0.738681543 0.249389549 1.004651192 1 13.01153472 -4.352391524 1.038791062 1.059214341 6.34E-14 0.939675402 0.061759888 0.271563488 0.252391835 0.009803819 0.30578085 4.44E-05 4.352391524 -1.059214341 down LREVMESAVGNSSGSGQNEES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 LREVMESAVGNSSGSGQNEESPR 23 1 Q9NVF7 Q9NVF7 FBXO28 F-box only protein 28 1 0 LREVMESAVGNS(0.001)SGS(0.009)GQNEES(0.99)PR 62.67 0.004701 0 665.17 516.73 496.03 517.14 653.63 736.65 560.95 394.03 855.08 635.67 TRUE FALSE FALSE 612.5210926 561.3938387 514.4133082 515.0002117 645.8358891 583.8604862 576.6887473 514.1679331 761.2798633 657.7594852 0.931223504 0.853494098 0.782069008 0.782961285 0.981872407 0.887650425 0.87674714 0.781695961 1.15738333 1 9.361416338 -7.617437455 1.517108025 0.978081145 0.852261517 0.47567667 0.082005482 0.242484189 1.140800821 0.013073268 0.013389301 2.41E-08 7.617437455 -0.125819627 LRGTQEVAPPTPLTPTSHTANT(ph)SPRPVSGMER ddPTM_HeLa_Curcumin_4h_R1 1 LRGTQEVAPPTPLTPTSHTANTSPRPVSGMER 32 2 H7BYT1;P48730-2;P48730 H7BYT1 CSNK1D Casein kinase I isoform delta 1 0 LRGTQEVAPPTPLTPT(0.018)S(0.018)HT(0.018)ANT(0.381)S(0.381)PRPVS(0.183)GMER 61.45 0.00032966 24324000 674.18 543.55 562.44 648.82 737.55 797.89 490.46 268.64 896.23 861.95 TRUE FALSE FALSE 620.8179416 590.53204 583.2845212 646.1353548 728.755198 632.3986199 504.2209876 350.5470993 797.9158113 891.9026983 0.696060168 0.662103659 0.653977751 0.724446014 0.817079261 0.709044407 0.565331833 0.393032895 0.89462204 1 9.800742518 -13.52287875 0.126249249 2.194967693 0.486640048 0.618983663 0.098928207 39.77063075 0.358577319 12.00408148 0.418594206 3.00E-14 13.52287875 -1.708327644 GQSTDS(ph)LPQTICR ddPTM_HeLa_Curcumin_4h_R1 1 GQSTDSLPQTICR 13 0 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 0 GQS(0.002)T(0.088)DS(0.882)LPQT(0.028)ICR 120.59 0.0024527 7765700 2284.4 2279.7 2104.5 2246.2 2572.6 2661.5 1726.5 788.16 2429.1 2259.2 TRUE FALSE FALSE 2103.58733 2476.74711 2182.494621 2236.90582 2541.923425 2109.474899 1774.940943 1028.466356 2162.633807 2337.707032 0.899850709 1.059477118 0.933604849 0.956880306 1.087357565 0.902369232 0.759265776 0.439946641 0.925108997 1 11.19087842 -4.351435402 1.767017442 0.96690421 0.322332385 0.890821587 0.057881444 0.17876221 0.634863016 0.008824644 0.1806634 4.45E-05 4.351435402 -0.644571825 down LRLDTGPQSLS(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 LRLDTGPQSLSGK 13 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 0 LRLDTGPQS(0.053)LS(0.947)GK 82.865 0.008453 59907000 1630.8 1335.2 1401.9 1390.1 1311.3 1946.4 1941.8 517.49 1585.7 1336.9 TRUE FALSE FALSE 1501.720459 1450.608738 1453.855647 1384.348135 1295.663604 1542.6947 1996.281682 675.2703188 1411.752677 1383.357175 1.085562345 1.04861475 1.050961872 1.000716344 0.936608149 1.115181767 1.44307032 0.488138805 1.020526515 1 10.43395799 -6.313912107 22.95550361 1.042896971 1.024777865 0.002023614 0.219939638 1911.727358 836330.4398 0.030999748 0.04735294 4.85E-07 6.313912107 -0.018119106 SVSQERLEDS(ph)VLMK ddPTM_HeLa_Curcumin_4h_R1 1 SVSQERLEDSVLMK 14 1 Q5T5U3;A0A087WW76;A0A452Q6Z5;E7ESW5;A0A1B0GV73;Q5T5U3-3 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 0 SVSQERLEDS(1)VLMK 101.66 0.008913 24651000 5599.6 4586.4 4960.8 5165.3 4128.1 5156.3 3434.4 1161.9 6765.3 5648.1 TRUE FALSE FALSE 5156.385751 4982.827979 5144.651612 5143.927357 4078.875104 4086.825257 3530.760021 1516.157961 6023.163516 5844.371055 0.882282405 0.852585836 0.880274638 0.880150714 0.69791515 0.69927546 0.604130023 0.25942192 1.03059225 1 12.51283206 -4.351019783 0.527180611 0.945471557 2.61E-24 0.904844432 0.066316688 0.781071256 0.154238147 0.013251877 0.444806798 4.46E-05 4.351019783 -0.945471557 down LRLS(ph)PSPT(ph)SQR ddPTM_HeLa_Curcumin_4h_R1 1 LRLSPSPTSQR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 LRLS(0.957)PS(0.043)PT(0.922)S(0.078)QR 126.56 0.014171 3166700000 5182.8 4352.3 4438.6 4824.5 4434 5236.4 3608.1 2795.1 5940.3 4679 TRUE FALSE FALSE 4772.575911 4728.493419 4603.098421 4804.537497 4381.127446 4150.311614 3709.333575 3647.313123 5288.663952 4841.594902 0.985744575 0.976639623 0.9507401 0.992346034 0.904893436 0.857219924 0.766138773 0.753328851 1.09233921 1 12.24126666 -5.081232397 0.965891732 0.991039673 0.722695178 0.875299449 0.036150873 0.090155493 0.126207167 0.002602341 0.01865079 8.29E-06 5.081232397 -0.268344495 LRLSPSPT(ph)SQR ddPTM_HeLa_Curcumin_4h_R1 1 LRLSPSPTSQR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 LRLS(0.005)PS(0.019)PT(0.976)SQR 143.55 0.010718 1989100000 2059 1294 1270 1716.3 1480.1 2201.9 1474.4 1694.2 2589.3 1915.8 TRUE FALSE FALSE 1896.027977 1405.847594 1317.067317 1709.198405 1462.450774 1745.201119 1515.767696 2210.753781 2305.260268 1982.373907 0.956443167 0.709173778 0.664388949 0.862197792 0.737727009 0.880359206 0.764622501 1.115205246 1.162878637 1 10.95301339 -7.407750309 6.479620383 0.980976158 0.812164561 0.347676583 0.131439914 0.212485785 10.67102647 0.019435716 0.022117962 3.91E-08 7.407750309 -0.168811597 LRLSPSPTSQR ddPTM_HeLa_Curcumin_4h_R1 1 LRLSPSPTSQR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 113.67 0.0017466 0 1020.1 659.38 946.86 978.26 795.78 819.94 836.87 959.72 1282.1 1078.5 FALSE FALSE TRUE 939.3580086 716.3738691 981.9514645 974.2122193 786.2908432 649.8752014 860.3503199 1252.33421 1141.456838 1115.977795 0.841735394 0.641924842 0.879902332 0.872967387 0.704575707 0.582337036 0.770938565 1.122185599 1.022831138 1 10.12409261 -8.539046445 0.772930285 0.990294197 0.788974068 0.247449655 0.142522052 0.659796237 0.809359709 0.06657906 0.031586147 2.89E-09 8.539046445 -0.201320129 LRMIVS(ph)STSANCSHQVK ddPTM_HeLa_Curcumin_4h_R1 1 LRMIVSSTSANCSHQVK 17 1 H7C5H5;Q8IWA4-3;Q8IWA4 H7C5H5 MFN1 Mitofusin-1 1 0 LRMIVS(0.25)S(0.25)T(0.25)S(0.25)ANCSHQVK 94.767 0.0018189 0 750.59 1317.8 1025.2 1022.9 577.44 0 711.13 501.46 945.07 1491.5 TRUE FALSE FALSE 691.1800095 1431.70476 1063.194814 1018.667511 570.5544051 0 731.0823939 654.3528456 841.3981854 1543.329514 0.447849927 0.927672767 0.688896833 0.660045377 0.369690594 0 0.473704667 0.423987774 0.545183759 1 10.59183041 -5.786663616 3.305165985 0.743785381 0.297363955 0.507746376 0.191317969 0.175343068 3.972715925 0.035318553 0.070254902 1.63E-06 5.786663616 -0.446421425 LRPVS(ph)PEEIR ddPTM_HeLa_Curcumin_4h_R1 2 LRPVSPEEIR 10 1 J3KNG6;Q08AE8-4;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8;K7EMJ7 J3KNG6 SPIRE1 Protein spire homolog 1 1 0 LRPVS(1)PEEIR;LRPVS(1)PEEIR ; 87.831 0.0097109 16880600 3926.8 4030.4 3459.44 4140.2 4418.7 4287.8 3555.8 2171.02 3526 4239.2 TRUE FALSE FALSE 3615.989636 4378.769817 3587.64989 4123.068949 4366.009888 3398.461947 3655.566178 2832.954004 3139.206622 4386.511884 0.824342834 0.998235029 0.817882177 0.939942501 0.995326128 0.774752705 0.83336516 0.645832971 0.715649861 1 12.09885846 -3.608422748 0.811061467 0.919641686 0.096864883 0.339835324 0.096425005 3.822507893 0.865751507 0.013125304 3.640961573 0.000246364 3.608422748 -0.822776803 LRQDLQDR ddPTM_HeLa_Curcumin_4h_R1 2 LRQDLQDR 8 1 P12270 P12270 TPR Nucleoprotein TPR 0 0 ; ; 93.143 0.016442 8982300 3070.7 2333.5 2802.4 2283.4 2632.4 3051.2 2478.8 2262.6 2939.8 2627.3 FALSE FALSE TRUE 2827.650855 2535.197342 2906.259409 2273.951896 2601.010349 2418.346726 2548.348457 2952.456324 2617.311295 2718.598479 1.040113454 0.932538351 1.069028557 0.836442716 0.956746783 0.889556418 0.937375812 1.086021473 0.962742867 1 11.40864737 -6.287772265 24.92882966 1.014983662 0.939006001 0.140493559 0.06942524 770.8748212 729770.239 0.009832282 0.01502171 5.15E-07 6.287772265 -0.075977661 LRS(ph)PPEALVQGR ddPTM_HeLa_Curcumin_4h_R1 2 LRSPPEALVQGR 12 1 Q9UHB6;F8VRN8;Q9UHB6-4 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 LRS(1)PPEALVQGR;LRS(1)PPEALVQGR ; 132.03 0.00096623 109218000 3369.5 2975.3 3090 3163.4 3309 3928.8 3089 3081.4 3807.6 3143.1 TRUE FALSE FALSE 3102.80052 3232.471674 3204.518118 3150.310689 3269.542336 3113.922593 3175.669026 4020.904675 3389.915806 3252.322491 0.954026093 0.993896418 0.985301466 0.968634168 1.00529463 0.957445826 0.976431161 1.23631795 1.042306172 1 11.6672546 -4.261083214 24.99496751 0.979067551 1.236318027 0.893553612 0.025679345 4.659032893 326831.396 0.002664436 0.02077472 5.48E-05 4.261083214 0.257250477 LRS(ph)PRGS(ph)PDGSLQTGKPSAPK ddPTM_HeLa_Curcumin_4h_R1 1 LRSPRGSPDGSLQTGKPSAPK 21 3 Q8IZL8;C9JFV4;E7EV54 Q8IZL8 PELP1 "Proline-, glutamic acid- and leucine-rich protein 1" 2 0 LRS(1)PRGS(0.999)PDGS(0.001)LQTGKPSAPK 62.648 0.0041003 145770000 2844.5 2514.5 2110.9 2568.3 2648.7 2792.4 2516.4 2015.2 2498 2297 TRUE FALSE FALSE 2619.354823 2731.842176 2189.131811 2557.673055 2617.115982 2213.224763 2587.003411 2629.625203 2223.97565 2376.820579 1.102041461 1.149368278 0.921033683 1.076090083 1.101099513 0.931170313 1.088430248 1.106362519 0.935693535 1 11.21481729 -9.604390827 1.441697905 1.000386348 1.062900865 0.163826589 0.074321821 0.811019941 3.055012562 0.047867045 0.011346354 2.49E-10 9.604390827 0.062514517 LRS(ph)PSNDSAHR ddPTM_HeLa_Curcumin_4h_R1 2 LRSPSNDSAHR 11 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 0 LRS(0.595)PS(0.02)NDS(0.385)AHR;LRS(0.992)PS(0.008)NDS(0.001)AHR ; 79.804 0.012309 40004000 1739.4 1427.7 1430.33 932.6 1771.73 2542.89 1288.05 1302.34 1866.34 1621.47 TRUE FALSE FALSE 1601.724655 1551.104026 1483.339288 928.7411483 1750.603277 2015.46595 1324.189216 1699.417471 1661.607171 1677.815962 0.954648597 0.924478049 0.884089389 0.553541729 1.043382181 1.201243757 0.789233889 1.012874779 0.990339351 1 10.71236876 -7.653144601 1.579673203 0.985265686 0.91210608 0.036548206 0.160035663 1.040679385 5.35022594 0.033717924 0.034080704 2.22E-08 7.653144601 -0.073159606 LRS(ph)YEDMIGEEVPSDQYYWAPLAQHER ddPTM_HeLa_Curcumin_4h_R1 1 LRSYEDMIGEEVPSDQYYWAPLAQHER 27 1 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12 O60716 CTNND1 Catenin delta-1 1 0 LRS(0.549)Y(0.451)EDMIGEEVPSDQYYWAPLAQHER 75.483 6.40E-05 2996500 375.57 265.19 265.81 395.44 548 405.23 426.99 542.8 291.49 552.52 TRUE FALSE FALSE 345.8432382 288.1118419 275.6611524 393.8037741 541.4654579 321.1807301 438.9701902 708.2972213 259.5142763 571.7200289 0.604917129 0.503938689 0.48216109 0.688805279 0.947081492 0.561779742 0.767806213 1.238888242 0.453918462 1 9.159165022 -4.263753845 6.100449019 0.748330393 1.25086797 0.383205857 0.194692832 0.117940149 22.12337421 0.029677712 0.245626753 5.45E-05 4.263753845 0.502537578 LRSDAGLESDT(ph)AMK ddPTM_HeLa_Curcumin_4h_R1 1 LRSDAGLESDTAMK 14 1 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 0 LRSDAGLES(0.039)DT(0.961)AMK 82.942 0.0091967 13123000 3529.4 2941.1 3403.7 3907.7 3493.6 4801.4 3567.2 3745.4 4229.4 4148.2 TRUE FALSE FALSE 3250.044266 3195.315579 3529.844116 3891.530973 3451.941102 3805.535517 3667.286031 4887.355218 3765.445401 4292.349641 0.757171372 0.744421085 0.82235708 0.906620219 0.804207809 0.886585631 0.854377285 1.138620016 0.877245732 1 12.06755188 -4.260172301 24.40944775 0.864149728 1.138620138 0.583575948 0.072213844 62.16314991 1197331.326 0.013944445 0.11634839 5.49E-05 4.260172301 0.27447041 LRTGDLGIPPNPEDRS(ph)PS(ph)PEPIYNSEGK ddPTM_HeLa_Curcumin_4h_R1 1 LRTGDLGIPPNPEDRSPSPEPIYNSEGK 28 2 Q15637-5;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-6 Q15637-5;Q15637-6 SF1 Splicing factor 1 2 0 LRT(0.004)GDLGIPPNPEDRS(0.992)PS(0.977)PEPIY(0.021)NS(0.007)EGK 47.12 0.0192 8722200 1831.5 1090.4 1359.3 1445.4 1551.8 1845.5 1358.2 1705.7 2188 1529.6 TRUE FALSE FALSE 1686.534842 1184.649317 1409.676854 1439.419318 1533.295799 1462.722497 1396.307437 2225.760078 1947.981874 1582.753486 1.065570133 0.748473674 0.890648396 0.909439992 0.968752122 0.924163181 0.88220146 1.406258206 1.230755068 1 10.62822086 -4.253646918 24.87730184 0.97654627 1.406258429 0.544631015 0.121943405 493.2065937 1574514.614 0.014880275 0.214790995 5.58E-05 4.253646918 0.429712159 LRTS(ph)TSDLSR ddPTM_HeLa_Curcumin_4h_R1 1 LRTSTSDLSR 10 1 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 0 LRT(0.042)S(0.779)T(0.136)S(0.042)DLSR 67.952 0.020443 16590000 880.49 807.98 899.14 783.22 815.05 863.12 431.63 310.24 825.31 591.68 TRUE FALSE FALSE 810.7982874 877.8181909 932.4629194 779.9792432 805.3310611 684.0991826 443.7403761 404.8307478 734.7755578 612.240836 1.324312656 1.433779224 1.523032873 1.273974549 1.315382793 1.117369412 0.724780756 0.661227942 1.200141374 1 9.257955464 -4.793417058 3.337171837 1.225112219 0.669966281 0.722665289 0.143066987 0.131619 2.968307929 0.027343525 0.10650795 1.61E-05 4.793417058 -0.555145938 LRVQS(ph)PEPPAPER ddPTM_HeLa_Curcumin_4h_R1 2 LRVQSPEPPAPER 13 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 LRVQS(1)PEPPAPER;LRVQS(1)PEPPAPER ; 84.352 0.0078259 61980000 4008.2 3508 2890.7 3385.7 2794.7 3161 2399 1911.5 4827.2 3473.4 TRUE FALSE FALSE 3690.946741 3811.215889 2997.831885 3371.69087 2761.375028 2505.372968 2466.309483 2494.307551 4297.668237 3594.100391 1.026945922 1.060408857 0.834097982 0.938118167 0.768307706 0.697079295 0.686210516 0.694000523 1.195756314 1 11.81141499 -5.876730269 0.945786962 1.01543709 0.672694926 0.803029096 0.075682196 0.123450643 0.212832283 0.008198317 0.024095111 1.33E-06 5.876730269 -0.342742164 LRVSGETEMGLRHAAQAGLEVLT(ph)S(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 LRVSGETEMGLRHAAQAGLEVLTSK 25 2 K7EIH6 K7EIH6 IMPA2 2 0 LRVS(0.001)GET(0.001)EMGLRHAAQAGLEVLT(0.999)S(0.999)K 40.381 0.019159 6601800 994.45 945.53 945.72 882.51 1067.2 1781.8 1431.1 668.66 1197.6 903.49 TRUE FALSE FALSE 915.7382332 1027.2574 980.7692151 878.8584075 1054.474337 1412.234595 1471.252814 872.5313559 1066.226276 934.8862103 0.979518388 1.098804741 1.049078705 0.940069923 1.127917307 1.510595171 1.573723944 0.933302199 1.140487756 1 9.868646968 -5.471846273 5.105395822 1.001669127 1.360425287 0.382316135 0.169184964 0.122000535 7.051131598 0.021652479 0.048472803 3.37E-06 5.471846273 0.35875616 QLSGQS(ph)TSSDTTYK ddPTM_HeLa_Curcumin_4h_R1 1 QLSGQSTSSDTTYK 14 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 0 QLS(0.007)GQS(0.942)T(0.026)S(0.007)S(0.013)DT(0.003)T(0.001)YK 135.14 0.0009239 4586500 1892.2 1693.6 1882.6 1503.5 1578.5 2083.7 1132 492.63 1872.6 1526.9 TRUE FALSE FALSE 1742.430373 1839.987237 1952.370812 1497.278915 1559.677418 1651.517132 1163.760873 642.8306192 1667.180465 1579.959661 1.10283219 1.164578617 1.235709278 0.947669078 0.98716281 1.045290695 0.73657632 0.40686521 1.05520445 1 10.62567201 -4.349617322 1.462224656 1.064372333 0.201790169 0.869524707 0.081757495 0.272247589 0.591436843 0.013022855 0.323453212 4.47E-05 4.349617322 -0.862582164 down LS(ph)CEPVMEEK ddPTM_HeLa_Curcumin_4h_R1 2 LSCEPVMEEK 10 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 0 LS(1)CEPVMEEK;LS(1)CEPVMEEK ; 136.53 0.001996 41126500 4321.5 3810.2 4034.8 3926 4024.9 5242.1 2965.91 1549.83 4042.5 3820.1 TRUE FALSE FALSE 3979.448715 4139.53671 4184.333237 3909.755252 3976.905696 4154.829369 3049.125452 2022.366032 3599.047864 3952.848191 1.006729458 1.047228861 1.058561583 0.989098256 1.006086119 1.051097631 0.771374286 0.51162249 0.910494836 1 11.94867683 -4.473021862 2.49834983 1.012370103 0.494643411 0.928482116 0.043559895 0.043268934 0.441731676 0.004293768 0.038555482 3.36E-05 4.473021862 -0.517726692 LS(ph)DGEINAQESTYK ddPTM_HeLa_Curcumin_4h_R1 1 LSDGEINAQESTYK 14 0 A0A3B3IRW6;Q2KHR3-2;Q2KHR3 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 0 LS(1)DGEINAQESTYK 144.97 4.48E-05 0 1233.2 1081.1 1034.3 1124.9 1334.3 1048.8 958.54 743.2 1195.5 832.82 TRUE FALSE FALSE 1135.590919 1174.545467 1072.632068 1120.245462 1318.389344 831.2670576 985.4340526 969.7982587 1064.356641 861.760433 1.317757088 1.362960542 1.244698674 1.299949985 1.529879179 0.96461502 1.143512762 1.125368747 1.235095741 1 9.75114305 -2.913350573 13.69594163 1.191846851 1.202274406 0 0.164603842 0 0 0.024748707 0 0.001220814 2.913350573 0.010427555 LS(ph)GDQPAAR ddPTM_HeLa_Curcumin_4h_R1 1 LSGDQPAAR 9 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 LS(1)GDQPAAR 111.52 0.0086577 28857000 1853.4 2148.1 1971.8 2247.4 1777.5 2418.9 1513.7 998.02 2496.7 1977.3 TRUE FALSE FALSE 1706.701434 2333.772192 2044.876643 2238.100854 1756.304473 1917.192873 1556.170348 1302.311704 2222.818256 2046.011028 0.834160428 1.140644972 0.999445562 1.09388504 0.858404207 0.937039365 0.760587468 0.636512553 1.086415579 1 10.99859821 -4.530894924 1.651875455 0.952764168 0.597047738 0.569903915 0.100404841 0.386269921 1.464277673 0.0151486 0.184776473 2.95E-05 4.530894924 -0.35571643 LS(ph)HQT(ph)VLMT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 LSHQTVLMTR 10 0 J3KNY7;Q9NXS3-2;Q9NXS3 J3KNY7 KLHL28 Kelch-like protein 28 3 0 LS(1)HQT(1)VLMT(1)R 77.644 0.015223 3481800 562.73 569.71 386.55 541.8 579.81 700.43 768.23 482.88 527.53 649.75 TRUE FALSE FALSE 518.1893267 618.9531938 400.875883 539.5581752 572.8961444 555.1529225 789.7844662 630.1078891 469.6612788 672.3287641 0.770738 0.920610908 0.596249788 0.802521332 0.852107146 0.825716453 1.174699802 0.93720204 0.698558955 1 9.393023063 -4.777745662 24.9821433 0.857792667 1.055950949 0.332261824 0.125628979 207.4512609 317828.3857 0.018467733 0.055641538 1.67E-05 4.777745662 0.198158282 ADSGPTQPPLSLS(ph)PAPETK ddPTM_HeLa_Curcumin_4h_R1 2 ADSGPTQPPLSLSPAPETK 19 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;X6RGP5;A0A0C4DH09;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 ADSGPTQPPLS(0.003)LS(0.996)PAPET(0.001)K;ADSGPTQPPLS(0.023)LS(0.975)PAPET(0.001)K ; 127.67 8.53E-05 277269000 16396.9 13064.5 15430.3 15301.3 13912.3 13275.3 9419.3 3221.5 13967.5 12217.2 TRUE FALSE FALSE 15099.06806 14193.73717 16002.16049 15237.98727 13746.40491 10521.85314 9683.580207 4203.72052 12435.30019 12641.74679 1.194381466 1.122767083 1.265818779 1.205370391 1.087381763 0.832310068 0.766000171 0.332526872 0.983669457 1 13.6259082 -4.349336188 1.063059239 1.118543432 0.040222958 0.870532093 0.09503451 0.434739113 0.425941798 0.016341388 0.508140396 4.47E-05 4.349336188 -1.078320474 down LS(ph)LGLSR ddPTM_HeLa_Curcumin_4h_R1 3 LSLGLSR 7 0 Q9NR12-2;Q9NR12;D6RAN1;H0Y8W6;D6RF83;H7BYK4;D6RH06;Q9NR12-3;Q9NR12-5;Q9NR12-6;Q9NR12-4 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 0 LS(1)LGLSR;LS(1)LGLSR;LS(1)LGLSR ;; 126.24 0.0087956 65600000 10665.4 9094.7 10502.5 11207.5 11536.4 14090.6 9796.3 7997.5 9983.4 9172.5 TRUE FALSE FALSE 9821.222336 9880.805343 10891.73189 11161.12633 11398.83596 11168.05073 10071.15781 10435.90093 8888.245997 9491.243692 1.034766639 1.041044321 1.147555815 1.175939286 1.200984437 1.176668842 1.061099908 1.099529342 0.936468 1 13.21238143 -6.828222763 3.739972141 1.01728202 1.145994018 0.686704463 0.046327583 0.101779833 2.854985167 0.007069248 0.009569914 1.49E-07 6.828222763 0.128711997 LS(ph)LPADIR ddPTM_HeLa_Curcumin_4h_R1 1 LSLPADIR 8 0 H0YBX5;E5RJM2;E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RIY8;E5RIU4;Q00537-2;Q00537;F8VZY6;F8VQZ9;F5H6Z0 H0YBX5;Q00537-2 CDK16;CDK17 Cyclin-dependent kinase 16;Cyclin-dependent kinase 17 1 0 LS(1)LPADIR 109.44 0.011459 3465800 3716.7 3817.4 3690.4 3828.3 4277.4 4474.3 3577.7 2074.3 3643.3 3480 TRUE FALSE FALSE 3422.519273 4147.359046 3827.16947 3812.459509 4226.394799 3546.279744 3678.080633 2706.744521 3243.639105 3600.929741 0.950454332 1.151746728 1.062828143 1.058743098 1.173695435 0.984823365 1.02142527 0.751679348 0.900778226 1 11.81415374 -4.260560601 24.11402807 1.014996684 0.751679224 0.507339299 0.081532628 30.4319496 834826.7133 0.011452312 0.092620423 5.49E-05 4.260560601 -0.26331746 LS(ph)NGSFSAPSLTNSR ddPTM_HeLa_Curcumin_4h_R1 1 LSNGSFSAPSLTNSR 15 0 O94806;O94806-2 O94806 PRKD3 Serine/threonine-protein kinase D3 1 0 LS(0.694)NGS(0.294)FS(0.012)APSLTNSR 177.07 7.86E-05 16939000 795.2 503.91 752.55 693.45 726.02 665.83 498.96 278.2 740.2 597.47 TRUE FALSE FALSE 732.2590809 547.465735 780.440165 690.5806876 717.3626857 527.7293525 512.9594747 363.0218993 659.0019119 618.232038 1.184440527 0.885534397 1.262374185 1.117025073 1.160345374 0.853610489 0.829719981 0.587193605 1.065945909 1 9.272004609 -4.715356594 1.424154479 1.092971766 0.586731567 0.693058921 0.108035834 0.265657848 0.814098762 0.016554542 0.150697141 1.93E-05 4.715356594 -0.506240199 LS(ph)PANQR ddPTM_HeLa_Curcumin_4h_R1 1 LSPANQR 7 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 0 LS(1)PANQR 112.11 0.015428 131750000 4586.2 3950.5 4582.4 3910.2 5176.6 5704.5 4643.3 4081.2 4394.7 3971.3 TRUE FALSE FALSE 4223.197431 4291.963617 4752.227775 3894.020628 5114.872426 4521.322397 4773.578501 5325.539092 3912.612405 4109.302379 1.027716396 1.044450668 1.156456093 0.94761112 1.244705781 1.100265198 1.161651799 1.295971579 0.952135434 1 12.00467778 -1 0.252805673 0.99678466 2.761692328 0.588962654 0.072888905 22.61191033 0.282946288 0.034119975 17.23976328 0.1 1 1.764907667 LS(ph)PDFAEELR ddPTM_HeLa_Curcumin_4h_R1 2 LSPDFAEELR 10 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 LS(1)PDFAEELR;LS(1)PDFAEELR ; 164.48 0.00058375 4059800 1841.8 2001.26 2008.82 2088.52 1897.55 2108.4 1181.25 907.51 1841.03 1488.86 TRUE FALSE FALSE 1696.019587 2174.239997 2083.268636 2079.878258 1874.922956 1671.094073 1214.392696 1184.205621 1639.073615 1540.597774 1.100884095 1.411296338 1.352246947 1.350046256 1.217010038 1.084704977 0.78826071 0.76866632 1.063920539 1 10.58927453 -4.78388865 4.298032315 1.133590316 0.769974191 0.552857655 0.142380155 0.150744333 6.305202958 0.025232468 0.090028528 1.64E-05 4.78388865 -0.363616125 LS(ph)PENNQVLTK ddPTM_HeLa_Curcumin_4h_R1 1 LSPENNQVLTK 11 0 Q16514-2;Q16514 Q16514-2 TAF12 Transcription initiation factor TFIID subunit 12 1 0 LS(1)PENNQVLTK 123.95 0.0036854 12636000 2593.8 2362.4 2705.2 2371.4 3183.1 2705 2431.1 2425 2339.8 2119.1 TRUE FALSE FALSE 2388.497993 2566.595329 2805.457092 2361.587775 3145.143611 2143.952508 2499.310123 3164.371337 2083.129794 2192.738567 1.089276227 1.170497645 1.279430724 1.077003803 1.434345005 0.977751083 1.139812178 1.443113823 0.95001284 1 11.0985181 -7.548157146 0.837882253 1.018666375 1.219039851 0.322433998 0.138925965 0.495403762 0.728784759 0.034003959 0.034112723 2.83E-08 7.548157146 0.200373476 LS(ph)PEVAPPAHR ddPTM_HeLa_Curcumin_4h_R1 4 LSPEVAPPAHR 11 0 Q8TAD8 Q8TAD8 SNIP1 Smad nuclear-interacting protein 1 1 0 LS(1)PEVAPPAHR;LS(1)PEVAPPAHR;LS(1)PEVAPPAHR;LS(1)PEVAPPAHR ;;; 107.37 0.0036302 206171000 30823.7 27227.1 26709.1 28721.2 29733.5 32164.5 26059.5 16878 29216.8 26096.7 TRUE FALSE FALSE 28383.97162 29580.4892 27698.96274 28602.35928 29378.94743 25493.22013 26790.65943 22024.0245 26011.79014 27003.55838 1.051119679 1.095429305 1.025752323 1.059207045 1.087965779 0.944068918 0.992115893 0.815597122 0.963272683 1 14.72086191 -3.508858318 1.031764243 1.034927549 0.120301722 0.676400559 0.044810397 2.923675954 0.791608696 0.006224787 4.295460045 0.000309843 3.508858318 -0.914625828 LS(ph)PGESAYQK ddPTM_HeLa_Curcumin_4h_R1 2 LSPGESAYQK 10 0 A0A0G2JHC2;Q6NYC8;Q6NYC8-2 A0A0G2JHC2 PPP1R18 Phostensin 1 0 LS(1)PGESAYQK;LS(1)PGESAYQK ; 163.12 0.00059689 232813000 8191 7674.5 8077.3 8181.3 8331.6 9670.7 7323.5 11680.8 7846 7745.4 TRUE FALSE FALSE 7542.673707 8337.849583 8376.651844 8147.447948 8232.251112 7664.887809 7528.9777 15242.22215 6985.31343 8014.552073 0.941122303 1.040338812 1.045180288 1.016581822 1.02716297 0.956371328 0.939413411 1.901818343 0.871578769 1 12.96840618 -4.259709739 25 0.985016369 1.901818649 0.965298353 0.052318698 15.78952504 228200.1491 0.006068917 0.052064802 5.50E-05 4.259709739 0.91680228 LS(ph)PGETPER ddPTM_HeLa_Curcumin_4h_R1 2 LSPGETPER 9 0 A0A0G2JHC2;Q6NYC8;Q6NYC8-2 A0A0G2JHC2 PPP1R18 Phostensin 1 0 LS(0.999)PGET(0.001)PER;LS(0.997)PGET(0.003)PER ; 128.35 0.0041784 24283000 5759.3 5005.4 4371.4 4590.6 5193.4 5649.6 4001.9 9637 5364.6 4765.2 TRUE FALSE FALSE 5303.445328 5438.044472 4533.407929 4571.605314 5131.472097 4477.809276 4114.182543 12575.27694 4776.116802 4930.790345 1.07557713 1.102874811 0.919407967 0.927154674 1.040699713 0.908132158 0.834386022 2.550357256 0.968631085 1 12.2676032 -4.257521351 24.9976479 1.007610387 2.550357852 0.969258659 0.08397768 49.02595494 312780.73 0.012308067 0.125018101 5.53E-05 4.257521351 1.542747465 LS(ph)PGTDSSSNLGGVK ddPTM_HeLa_Curcumin_4h_R1 2 LSPGTDSSSNLGGVK 15 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;A0A0G2JQF5;A0A0G2JQF4;A0A1W2PRR3;I3L233;A0A1W2PPV8 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 0 LS(1)PGTDSSSNLGGVK;LS(1)PGTDSSSNLGGVK ; 217.39 2.57E-14 34101000 5529.3 4781 6332.4 5560.5 6620.4 7244.1 5431.8 4589.3 5315 4743 TRUE FALSE FALSE 5091.650071 5194.248336 6567.084315 5537.492124 6541.456054 5741.592002 5584.201689 5988.556443 4731.957797 4907.818897 1.037456796 1.05836186 1.338086114 1.128300013 1.332864189 1.16988669 1.13781739 1.2202073 0.964167158 1 12.2608663 -6.916869624 7.248987374 1.019231356 1.215623741 0.681130639 0.069523582 0.095145779 7.058468607 0.01018465 0.0134088 1.21E-07 6.916869624 0.196392385 LS(ph)PIPEEVPK ddPTM_HeLa_Curcumin_4h_R1 2 LSPIPEEVPK 10 0 Q96T23-3;Q96T23-2;Q96T23;H0YER1;H0YCN2 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 0 LS(1)PIPEEVPK;LS(1)PIPEEVPK ; 121.68 0.0042757 208373000 11364.1 10473.2 11993.3 10660.3 12031.4 10588.9 9940.3 8748.7 9191.6 9381.7 TRUE FALSE FALSE 10464.61949 11378.45674 12437.78225 10616.1905 11887.93341 8392.642779 10219.19807 11416.13836 8183.304476 9707.713377 1.077969558 1.172104727 1.281226769 1.093583019 1.224586363 0.864533434 1.052688483 1.175986343 0.842969313 1 13.2449158 -8.18415768 1.220042494 1.016326011 1.116926089 0.231767642 0.12050282 0.608166448 1.863687323 0.02942934 0.02234684 6.54E-09 8.18415768 0.100600078 LS(ph)PQQAFPR ddPTM_HeLa_Curcumin_4h_R1 1 LSPQQAFPR 9 0 A0A1B0GTT1;A0A1B0GVM0;Q9BUH8 A0A1B0GTT1 BEGAIN Brain-enriched guanylate kinase-associated protein 1 0 LS(1)PQQAFPR 119.03 0.0064869 23712000 1919.4 1464.8 1717.7 1239.8 1677.1 1942.7 1191.3 669.81 1929.9 1670.6 TRUE FALSE FALSE 1767.477465 1591.410785 1781.359473 1234.670036 1657.101678 1539.762121 1224.724672 874.0319856 1718.194798 1728.653226 1.022459241 0.920607304 1.030489775 0.714238124 0.958608501 0.890729325 0.708484879 0.505614413 0.993949956 1 10.75543277 -3.81868092 0.513428351 1.004567447 1.05E-18 0.736943149 0.085057668 2.103138503 0.271075904 0.016521586 1.402015447 0.000151817 3.81868092 -1.004567447 LS(ph)PSPTSQR ddPTM_HeLa_Curcumin_4h_R1 2 LSPSPTSQR 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 LS(0.992)PS(0.007)PTSQR;LS(0.974)PS(0.026)PTSQR ; 133.91 0.0033041 79737000 5237 5777.1 5505.1 5677.4 5564.3 6093.9 4679 4079.1 6395.9 5142.7 TRUE FALSE FALSE 4822.485924 6276.446782 5709.123849 5653.908423 5497.949357 4829.956448 4810.280147 5322.798812 5694.285772 5321.408442 0.906242394 1.179470971 1.072859547 1.062483454 1.033175599 0.907646256 0.903948682 1.000261279 1.070071173 1 12.37759243 -3.914499737 15.95414577 0.983080073 1.396751294 0 0.090085515 95864502.61 237016735.2 0.013104269 1377921429 0.000121759 3.914499737 0.41367122 LS(ph)PSWNPK ddPTM_HeLa_Curcumin_4h_R1 1 LSPSWNPK 8 0 Q96BY7 Q96BY7 ATG2B Autophagy-related protein 2 homolog B 1 0 LS(0.886)PS(0.114)WNPK 96.143 0.01731 19692000 2183.3 2064.1 2256.9 2485.2 1866.1 1982.1 1997 2400.4 2169.3 1824.6 TRUE FALSE FALSE 2010.489501 2242.511607 2340.542699 2474.916901 1843.847976 1570.990117 2053.030445 3132.27091 1931.333217 1888.004714 1.064875255 1.187768012 1.239691131 1.310863729 0.976611956 0.832090145 1.087407478 1.659037653 1.022949362 1 10.88264665 -4.264351688 5.858354024 1.0596516 1.675830528 0.629422729 0.132533586 0.066815741 10.35657733 0.019582254 0.163955016 5.44E-05 4.264351688 0.616178928 LS(ph)S(ph)EDEEEDEAEDDQSEASGKK ddPTM_HeLa_Curcumin_4h_R1 1 LSSEDEEEDEAEDDQSEASGKK 22 1 G3V4G1;Q8NEJ9-2;Q8NEJ9 G3V4G1 NGDN Neuroguidin 2 0 LS(1)S(1)EDEEEDEAEDDQSEASGKK 84.602 0.0002562 5169400 2362.7 1924.3 2121.8 2259.4 2223.1 2154.7 1668.4 1327.6 1691.5 1522.7 TRUE FALSE FALSE 2175.689802 2090.627917 2200.435775 2250.051201 2196.590984 1707.790932 1715.210814 1732.379128 1505.946682 1575.613712 1.38085229 1.326865781 1.396557899 1.428047487 1.394117713 1.083889356 1.088598558 1.099494829 0.955784194 1 10.62169816 -3.278607482 11.44014043 1.219155446 1.212152114 0 0.176216032 0 0 0.02643429 12164090.7 0.000526493 3.278607482 -0.007003332 EATQPEPIY(ph)AESTK ddPTM_HeLa_Curcumin_4h_R1 2 EATQPEPIYAESTK 14 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 0 EAT(0.001)QPEPIY(0.997)AES(0.002)TK;EATQPEPIY(0.975)AES(0.013)T(0.013)K ; 184.98 0.00036691 41641000 7764.6 6780.8 6368.1 6819.3 6797.5 8148.3 4854 1184.18 7825.9 7625.5 TRUE FALSE FALSE 7150.023717 7366.902137 6604.107388 6791.083543 6716.444252 6458.25073 4990.190176 1545.231031 6967.418349 7890.485557 0.906157633 0.933643701 0.836970975 0.860667382 0.851207977 0.818485844 0.632431317 0.19583472 0.883015158 1 12.94589837 -4.349049891 1.239711981 0.933429417 8.88E-32 0.938414384 0.054169386 0.238619328 0.3415701 0.009588333 0.271793237 4.48E-05 4.349049891 -0.933429417 down LS(ph)SPVLHR ddPTM_HeLa_Curcumin_4h_R1 7 LSSPVLHR 8 0 Q16643-3;Q16643;Q16643-2;D6R9W4;D6RCR4 Q16643-3 DBN1 Drebrin 1 0 LS(0.875)S(0.125)PVLHR;LS(0.5)S(0.5)PVLHR;LS(0.5)S(0.5)PVLHR;LS(0.5)S(0.5)PVLHR;LS(0.5)S(0.5)PVLHR;LS(0.639)S(0.361)PVLHR;LS(0.5)S(0.5)PVLHR ;;;;;; 111.06 0.0051905 2007308500 41643.4 31684.8 31856.2 33489.7 33745.5 35263.8 25386.1 18246.2 38858 32763.9 TRUE FALSE FALSE 38347.28095 34423.49293 33036.8188 33351.1285 33343.10695 27949.69038 26098.36564 23809.38238 34595.37462 33902.44309 1.131106713 1.015369094 0.9744672 0.983738205 0.983501598 0.824415229 0.769807815 0.702291051 1.020438985 1 15.04910162 -4.99009306 0.738477229 1.057503676 0.636319113 0.887129785 0.041974266 0.365708065 0.24536099 0.009819767 0.103944116 1.02E-05 4.99009306 -0.421184563 LS(ph)VASTPISQR ddPTM_HeLa_Curcumin_4h_R1 1 LSVASTPISQR 11 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7;H0YMD2 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 0 LS(0.3)VAS(0.233)T(0.233)PIS(0.233)QR 107.34 0.0076934 14875000 2502.9 2365.9 3127.7 3013.8 2911.3 5625.3 5863.2 2677.6 3404.8 2294.5 TRUE FALSE FALSE 2304.792824 2570.397854 3243.615313 3001.329694 2876.584649 4458.54937 6027.705612 3493.987914 3031.301958 2374.233704 0.970752298 1.082622089 1.366173561 1.264125637 1.211584455 1.877889848 2.538800456 1.471627628 1.276749611 1 11.21324624 -5.290429596 2.7075395 1.046194995 2.052331384 0.613614513 0.281117566 0.10550227 1.522341268 0.037845042 0.102591836 5.12E-06 5.290429596 1.006136389 LSAEYEKVELPSEEQVS(ph)GSQGPSEEKPAPLATEVFDEK ddPTM_HeLa_Curcumin_4h_R1 1 LSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEK 38 2 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 LS(0.077)AEY(0.067)EKVELPS(0.205)EEQVS(0.453)GS(0.164)QGPS(0.025)EEKPAPLAT(0.009)EVFDEK 49.19 0.0022156 4540100 1753.8 1812.6 2343.7 1666.2 2001.8 1946.6 1437.9 1697.5 1483.3 1533.7 TRUE FALSE FALSE 1614.984879 1969.273067 2430.559584 1659.305706 1977.929842 1542.853217 1478.243604 2215.059936 1320.585701 1586.995961 1.017636414 1.240880957 1.531547429 1.045563912 1.246335776 0.972184716 0.931472821 1.395756505 0.832129214 1 10.63208274 -7.277858684 20.31493091 1.008328188 1.185320369 0.257657781 0.182089468 88.21865743 109148.5763 0.029465676 0.033796885 5.27E-08 7.277858684 0.17699218 LSAFPEPPEDGTLLS(ph)EAK ddPTM_HeLa_Curcumin_4h_R1 1 LSAFPEPPEDGTLLSEAK 18 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 0 LSAFPEPPEDGT(0.004)LLS(0.996)EAK 182.28 2.91E-19 0 1712 1504.6 1555.9 1908.4 2050.9 3401.5 2132.9 515.72 1581.6 1883.7 TRUE FALSE FALSE 1576.493394 1634.65092 1613.563023 1900.503546 2026.444357 2695.990557 2192.743434 672.9606539 1408.102437 1949.158435 0.808807209 0.838644458 0.827825483 0.975038002 1.039650918 1.383156191 1.124969317 0.345257031 0.722415588 1 10.92863565 -6.047845152 6.731540307 0.895455915 1.012810487 0.03411747 0.255397208 0.635002873 72.1790417 0.037331879 0.062822069 8.96E-07 6.047845152 0.117354572 LSAK(ac)PAPPKPEPK ddPTM_HeLa_Curcumin_4h_R1 2 LSAKPAPPKPEPK 13 2 Q15651;A0A087WZE9;Q15651-2;P05204 Q15651;P05204 HMGN3;HMGN2 High mobility group nucleosome-binding domain-containing protein 3;Non-histone chromosomal protein HMG-17 0 1 ; LSAK(1)PAPPKPEPK;LSAK(1)PAPPKPEPK 81.904 0.0076414 6718900 5704.8 4709.5 5323.6 6235 6920.7 7526 6663.4 5934.7 5475.9 5340.5 FALSE TRUE FALSE 5253.25906 5116.568195 5520.897299 6209.201222 6838.175173 5965.022764 6850.35707 7744.16271 4875.20747 5526.081977 0.950629955 0.925894371 0.99906178 1.123617284 1.237436433 1.079430741 1.23964087 1.401383972 0.882217725 1 12.43204125 -4.146138963 0.453173288 0.968051467 1.705464771 0.80002568 0.070403052 1.690837685 0.216427377 0.0161652 0.682251089 7.14E-05 4.146138963 0.737413304 LSAKPAPPKPEPKPK ddPTM_HeLa_Curcumin_4h_R1 1 LSAKPAPPKPEPKPK 15 3 P05204 P05204 HMGN2 Non-histone chromosomal protein HMG-17 0 0 34.444 0.019225 6691800 7824 5424.4 6735.8 8371.9 6091.2 8966.5 7011.8 6656.8 9504.7 8351.2 FALSE FALSE TRUE 7204.722144 5893.260965 6985.434673 8337.259296 6018.566418 7106.746827 7208.532237 8686.427676 8462.05819 8641.403578 0.833744435 0.681979601 0.808368063 0.964803833 0.696480191 0.822406541 0.834185346 1.005210276 0.979245803 1 13.07704995 -8.943569492 0.908185559 0.993945856 0.827283472 0.30410454 0.094998334 0.502148074 0.792522915 0.050182797 0.018396737 1.14E-09 8.943569492 -0.166662383 LSAMLVPVT(ph)PEVKPK ddPTM_HeLa_Curcumin_4h_R1 4 LSAMLVPVTPEVKPK 15 1 Q5JSL0;Q5JSK6;P82970;Q5JSK7;Q5JSK8 Q5JSL0 HMGN5 High mobility group nucleosome-binding domain-containing protein 5 1 0 LS(0.012)AMLVPVT(0.988)PEVKPK;LSAMLVPVT(1)PEVKPK;LSAMLVPVT(1)PEVKPK;LSAMLVPVT(1)PEVKPK ;;; 93.753 0.0035417 519433000 22902.5 18501.8 19476.5 21886.7 19452.7 31683.9 29473.7 11720.9 23450 18709.3 TRUE FALSE FALSE 21089.74296 20101.01315 20198.31622 21796.13863 19220.73926 25112.30199 30300.6527 15294.54845 20877.59367 19359.44678 1.089377356 1.038305142 1.043331271 1.125865779 0.99283515 1.297160103 1.565161083 0.790030243 1.078418919 1 14.24075011 -5.259966829 24.99542649 1.046486665 1.252221544 0.139586904 0.181065776 142.195998 2413634.507 0.022981106 0.055217967 5.50E-06 5.259966829 0.205734879 EHSNPS(ph)PSQDTDGTK ddPTM_HeLa_Curcumin_4h_R1 2 EHSNPSPSQDTDGTK 15 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 0 EHS(0.012)NPS(0.967)PS(0.02)QDTDGTK;EHS(0.01)NPS(0.96)PS(0.031)QDTDGTK ; 97.45 0.0022848 19513500 7210.7 6377.3 7291.3 6498.2 7162.7 7686.4 4357.7 1246.4 7062.2 6410.7 TRUE FALSE FALSE 6639.965486 6928.525395 7561.521992 6471.31217 7077.289481 6092.153996 4479.965334 1626.421622 6287.494329 6633.471348 1.000978995 1.044479584 1.139904221 0.975554401 1.066905864 0.918396067 0.675357607 0.245184088 0.947843746 1 12.69554833 -4.348585814 1.518858474 1.017214766 0.026197436 0.955620106 0.052202747 0.123019727 0.294065293 0.007166168 0.172625331 4.48E-05 4.348585814 -0.99101733 down LSAS(ph)SSISSADLFEEPR ddPTM_HeLa_Curcumin_4h_R1 1 LSASSSISSADLFEEPR 17 0 H0Y6A0;Q9NP61-2;Q9NP61 H0Y6A0 ARFGAP3 ADP-ribosylation factor GTPase-activating protein 3 1 0 LS(0.035)AS(0.953)S(0.012)S(0.001)ISSADLFEEPR 112.12 0.0010421 4254200 446.45 438.76 373.3 424.93 451.73 555.8 472.67 512.31 658.42 435.22 TRUE FALSE FALSE 411.1130114 476.6844593 387.1348264 423.1717523 446.3434148 440.5208148 485.9318481 668.5109606 586.1929733 450.3438626 0.912886897 1.058489965 0.859642728 0.939663638 0.991116904 0.978187673 1.079024027 1.48444559 1.301656405 1 8.81488319 -4.158886325 1.843947429 0.958874851 1.755520778 0.567686712 0.119481176 0.24346105 0.674332839 0.007389272 0.363050473 6.94E-05 4.158886325 0.796645928 LSASTASELS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 6 LSASTASELSPK 12 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 LSASTAS(0.003)ELS(0.997)PK;LSASTAS(0.009)ELS(0.991)PK;LSASTAS(0.004)ELS(0.996)PK;LSAST(0.001)AS(0.077)ELS(0.922)PK;LSAS(0.001)TAS(0.009)ELS(0.99)PK;LSASTAS(0.024)ELS(0.976)PK ;;;;; 202.61 7.39E-09 1645524000 25559.4 19803.3 23454.5 24272.1 22298.7 24963 22829.2 8369.54 26345.7 20732.7 TRUE FALSE FALSE 23536.34652 21515.00901 24323.7444 24171.66848 22032.80257 19785.39241 23469.72591 10921.37422 23455.64262 21453.15978 1.097103959 1.002882989 1.133807078 1.126718336 1.027018993 0.922260059 1.09399856 0.509079983 1.093342093 1 14.38890253 -4.258466577 24.99330992 1.048010282 0.509079786 0.868063744 0.063821122 74.5306199 626570.4925 0.00903526 0.085636891 5.51E-05 4.258466577 -0.538930496 LSCFAQTVSPAEK ddPTM_HeLa_Curcumin_4h_R1 2 LSCFAQTVSPAEK 13 0 Q16658 Q16658 FSCN1 Fascin 0 0 ; ; 231.67 1.03E-37 8498600 3618.8 2866 3166.6 3160 3962.9 5673.8 4607.1 4312 4596.9 3385.4 FALSE FALSE TRUE 3332.368161 3113.724269 3283.956982 3146.924757 3915.645006 4496.989923 4736.362827 5626.70895 4092.631571 3503.042398 0.951278284 0.888862856 0.937458531 0.898340471 1.117784075 1.283738366 1.352071225 1.606234898 1.168307747 1 11.77439273 -4.878150524 1.075314013 0.960300743 1.618357107 0.850906669 0.086182635 0.143389134 0.235552603 0.009360021 0.083569743 1.32E-05 4.878150524 0.658056364 LSCS(ph)ENELFVS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 LSCSENELFVSR 12 0 A0A1B0GUQ4;Q68DX3-2;Q68DX3 A0A1B0GUQ4 FRMPD2 FERM and PDZ domain-containing protein 2 2 0 LS(0.464)CS(0.536)ENELFVS(1)R 65.038 0.018966 3905600 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 LSDDFDS(ph)PVKGPLCK ddPTM_HeLa_Curcumin_4h_R1 2 LSDDFDSPVKGPLCK 15 1 Q96T23-3;Q96T23-2;Q96T23;H0YER1;H0YCN2 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 0 LSDDFDS(1)PVKGPLCK;LS(0.001)DDFDS(0.999)PVKGPLCK ; 164.41 0.0024147 267285000 6245.9 5191 5435.7 6273.2 5595.2 7000.4 5879 1574.25 6180.1 5604.7 TRUE FALSE FALSE 5751.530424 5639.686909 5637.151824 6247.243161 5528.480894 5548.438129 6043.948917 2054.231578 5502.158492 5799.462908 0.991735013 0.972449863 0.972012739 1.077210642 0.953274636 0.956715858 1.042156664 0.354210659 0.948735871 1 12.50170358 -4.258882043 24.99902269 0.99507259 0.354210433 0.959406728 0.039252958 26.45659585 258608.7422 0.004570757 0.041702895 5.51E-05 4.258882043 -0.640862158 LSDGVAVLK ddPTM_HeLa_Curcumin_4h_R1 2 LSDGVAVLK 9 0 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 ; ; 140.5 1.64E-05 47338000 14195.3 12254 12360.5 14851.7 14533.9 21723 15635.2 14593 16080.8 11614.3 FALSE FALSE TRUE 13071.72703 13313.18116 12818.591 14790.2476 14360.59273 17217.40493 16073.88163 19042.33852 14316.77647 12017.89606 1.087688474 1.107779689 1.066625218 1.230685265 1.19493401 1.432647183 1.337495478 1.58449852 1.191288092 1 13.55289673 -1 0.258778658 1.002423321 4.852152562 0.796026018 0.077618194 8.322365343 0.10470139 0.025180532 14.28321019 0.1 1 3.849729242 LSDLDS(ph)ETR ddPTM_HeLa_Curcumin_4h_R1 1 LSDLDSETR 9 0 Q9Y266 Q9Y266 NUDC Nuclear migration protein nudC 1 0 LS(0.001)DLDS(0.962)ET(0.037)R 100.09 0.01308 17156000 2810.8 2433.6 2195.3 2417.6 2475 3810.7 2461.2 2477.6 2709.1 2463.7 TRUE FALSE FALSE 2588.322214 2643.94954 2276.659749 2407.596612 2445.487241 3020.317865 2530.254648 3233.008835 2411.918508 2549.313392 1.015301698 1.037122211 0.893048205 0.944409824 0.959272897 1.184757384 0.99252397 1.268188072 0.946105142 1 11.31589302 -1.000004439 0.871295572 0.997809504 105.3242084 0.552089043 0.073626512 429.8201639 1.024666538 0.010676915 89048.96624 0.099998978 1.000004439 104.3263989 LSDPPTSPSS(ph)PSQMMPHVQTHF ddPTM_HeLa_Curcumin_4h_R1 1 LSDPPTSPSSPSQMMPHVQTHF 22 0 Q13496-2;Q13496 Q13496-2 MTM1 Myotubularin 1 0 LSDPPT(0.002)S(0.009)PS(0.19)S(0.609)PS(0.19)QMMPHVQTHF 62.468 0.0030691 8474800 1760.8 1584.7 1432.6 1579.2 1733.7 2384.3 1838.3 1419 1898.1 1792.3 TRUE FALSE FALSE 1621.430822 1721.674407 1485.693416 1572.665689 1713.02676 1889.769303 1889.87775 1851.646568 1689.883179 1854.582292 0.874283567 0.928335407 0.801093283 0.847989165 0.923672553 1.018973012 1.019031487 0.998417043 0.911193419 1 10.85687857 -5.269051932 12.62504886 0.919570382 1.012834968 0.461292555 0.053036096 0.758073222 1256.783882 0.009952264 0.023075177 5.38E-06 5.269051932 0.093264585 LSDQFHDILIR ddPTM_HeLa_Curcumin_4h_R1 3 LSDQFHDILIR 11 0 H0Y9X3;A0A024QZ42;A0A087WZ38;O75340-2;O75340 H0Y9X3 PDCD6 Programmed cell death protein 6 0 0 ;; ;; 124.21 0.0029147 35850500 17298.7 14615.3 13310.6 13303.9 16918.6 25908.6 16342.9 13987.1 19718.5 14671.6 FALSE FALSE TRUE 15929.48964 15878.58141 13803.90255 13248.85199 16716.85674 20534.86431 16801.43779 18251.7024 17555.42988 15181.43701 1.049274165 1.045920844 0.909261919 0.872700785 1.101137971 1.352629814 1.106709317 1.202238128 1.156374714 1 13.89002074 -5.52020693 24.99711613 1.005992137 1.212100752 0.524029887 0.091757737 54.76509807 512373.2417 0.011510045 0.023355481 3.02E-06 5.52020693 0.206108615 LSDVDANTAIKHEEQS(ph)NEDIPIAEQSSK ddPTM_HeLa_Curcumin_4h_R1 2 LSDVDANTAIKHEEQSNEDIPIAEQSSK 28 1 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 LSDVDANTAIKHEEQS(1)NEDIPIAEQSSK;LSDVDANTAIKHEEQS(1)NEDIPIAEQSSK ; 116.08 3.23E-10 19327000 3738.4 3299.59 3079.7 3772.5 2918.3 4098.5 3311.4 2488.5 4142.2 3703.1 TRUE FALSE FALSE 3442.501695 3584.791857 3193.836391 3756.890395 2883.501179 3248.4249 3404.308972 3247.232194 3687.811023 3831.782449 0.898407397 0.935541593 0.833511932 0.980455035 0.752522153 0.847758176 0.888440045 0.847446909 0.962427035 1 11.90379994 -9.523864926 0.20445733 1.105361307 0.828000499 0.412007499 0.055900586 5.725412673 0.329854575 0.428401041 0.080169959 2.99E-10 9.523864926 -0.277360808 LSEAVWQPEEHYSS(ph)SPEK ddPTM_HeLa_Curcumin_4h_R1 1 LSEAVWQPEEHYSSSPEK 18 0 F5H269;Q9Y485 F5H269 DMXL1 DmX-like protein 1 1 0 LSEAVWQPEEHYS(0.121)S(0.439)S(0.439)PEK 75.703 0.0044105 4460300 1838.3 2155.1 1781.7 1377.9 2336.5 3990.7 1841.9 1493 2123.1 2311.9 TRUE FALSE FALSE 1692.796615 2341.377241 1847.731369 1372.198615 2308.638764 3162.983836 1893.578757 1948.208827 1890.201242 2392.238353 0.707620381 0.978739112 0.772385982 0.573604471 0.965053821 1.322185907 0.79155104 0.814387423 0.790139176 1 11.22414543 -5.55188276 24.99913315 0.840022781 0.988597353 0.15911005 0.179127001 348.4056928 300296.6899 0.028285282 0.056571188 2.81E-06 5.55188276 0.148574571 LSEDYGVLK ddPTM_HeLa_Curcumin_4h_R1 1 LSEDYGVLK 9 0 P32119;A6NIW5 P32119 PRDX2 Peroxiredoxin-2 0 0 124.23 0.0010303 3750300 3391.7 2852.7 3198.6 2570.6 2885.4 3743.8 3071.2 2509.3 3051.5 3372.7 FALSE FALSE TRUE 3123.243366 3099.274677 3317.14293 2559.963538 2850.99349 2967.293679 3157.369606 3274.374019 2716.758084 3489.901074 0.894937507 0.888069493 0.950497696 0.7335347 0.816926735 0.850251516 0.904716076 0.938242646 0.778462778 1 11.76897043 -8.599236518 0.526451923 1.006252092 0.860540302 0 0.089682362 0.749869383 0.407315269 0.051105055 0.017589765 2.52E-09 8.599236518 -0.14571179 LSEEAECPNPST(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 3 LSEEAECPNPSTPSK 15 0 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 0 LSEEAECPNPS(0.095)T(0.853)PS(0.053)K;LSEEAECPNPS(0.002)T(0.997)PS(0.001)K;LSEEAECPNPS(0.12)T(0.879)PS(0.001)K ;; 218.2 6.67E-14 146901000 12125.2 10233.7 10800 11408.4 11035.7 15535.1 15337.7 11628.3 13117.1 10247 TRUE FALSE FALSE 11165.47763 11118.25543 11200.2575 11361.19506 10904.10649 12312.94514 15768.03458 15173.71514 11678.18695 10603.08249 1.053040721 1.048587092 1.056320887 1.071499262 1.028390234 1.161260903 1.487117977 1.431066405 1.101395463 1 13.37219612 -4.888513076 3.171233235 1.034382022 1.464696977 0.955678052 0.034379438 0.029489162 0.580937066 0.004646594 0.016769329 1.29E-05 4.888513076 0.430314955 LSEELSGGR ddPTM_HeLa_Curcumin_4h_R1 1 LSEELSGGR 9 0 B4DXW1;P61158;Q9P1U1-2;Q9P1U1 B4DXW1 ACTR3;ACTR3B Actin-related protein 3;Actin-related protein 3B 0 0 114.89 0.00011479 0 1249.2 1099.5 1375.5 1150.3 1186.2 1715.2 1082.4 928.37 1303.1 1317.8 FALSE FALSE TRUE 1150.324502 1194.535881 1426.47724 1145.540363 1172.05534 1359.448186 1112.769231 1211.425739 1160.15319 1363.593452 0.843597848 0.876020546 1.046116229 0.84008937 0.859534297 0.996960042 0.816056449 0.888406832 0.85080578 1 10.41319786 -9.501476013 1.236446009 1.000273579 0.891836062 0 0.082257208 0.516582192 1.407833347 0.047464027 0.011386061 3.15E-10 9.501476013 -0.108437517 RAELPGSSS(ph)PLLAQPR ddPTM_HeLa_Curcumin_4h_R1 3 RAELPGSSSPLLAQPR 16 1 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 0 RAELPGS(0.002)S(0.052)S(0.947)PLLAQPR;RAELPGS(0.12)S(0.12)S(0.76)PLLAQPR;RAELPGS(0.004)S(0.199)S(0.797)PLLAQPR ;; 129.89 0.00021921 79033000 4117.3 2860.73 3892.3 4092.8 4307.1 5420.5 3100.41 1285.04 5157.3 3775.7 TRUE FALSE FALSE 3791.41136 3107.998754 4036.552062 4075.865078 4255.740646 4296.227198 3187.39916 1676.84278 4591.557093 3906.905294 0.970438512 0.795514229 1.033184006 1.04324645 1.089286872 1.099649691 0.815837324 0.429199751 1.175241463 1 11.93181057 -4.348446974 2.909309229 0.992729566 0.383500023 0.762797846 0.100277682 0.101950802 1.318081812 0.011688587 0.129616075 4.48E-05 4.348446974 -0.609229543 down LSEGS(ph)QPAEEEEDQETPSR ddPTM_HeLa_Curcumin_4h_R1 2 LSEGSQPAEEEEDQETPSR 19 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 LSEGS(1)QPAEEEEDQETPSR;LSEGS(1)QPAEEEEDQETPSR ; 203.26 2.31E-13 44048000 2781.58 2250.66 2181.62 2218.7 2293.71 2682.39 1778.88 2102.58 2802.24 2463.62 TRUE FALSE FALSE 2561.415008 2445.197022 2262.472756 2209.519607 2266.359006 2126.032077 1828.790585 2743.646963 2494.841283 2549.230612 1.004779637 0.959190201 0.887511999 0.866739791 0.889036479 0.833989702 0.71738923 1.076264717 0.978664414 1 11.31584617 -6.838307596 2.070708436 1.002509312 0.86584854 0.288435938 0.082763944 0.234275768 2.051414934 0.012791996 0.017773397 1.45E-07 6.838307596 -0.136660772 LSEGSQPAEEEEDQET(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 LSEGSQPAEEEEDQETPSR 19 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 LSEGSQPAEEEEDQET(1)PSR;LSEGSQPAEEEEDQET(0.999)PS(0.001)R ; 369.98 1.16E-200 39261000 1395.54 1377.95 1439.98 1543.88 1425.67 2175.5 2062.11 1125.98 1579.3 1055.27 TRUE FALSE FALSE 1285.081536 1497.053858 1493.346926 1537.491834 1408.669816 1724.276777 2119.967257 1469.286119 1406.054741 1091.940554 1.17687866 1.371003076 1.367608264 1.408036205 1.290060902 1.579094 1.941467646 1.345573359 1.287666015 1 10.0926786 -6.390245975 0.314063984 0.976419958 1.758876742 0.410380638 0.181589789 0.906581634 0.191735257 0.10290529 0.264149985 4.07E-07 6.390245975 0.782456784 LSEPSLPIEDS(ph)QDLYNASPEPK ddPTM_HeLa_Curcumin_4h_R1 1 LSEPSLPIEDSQDLYNASPEPK 22 0 Q9HAW4-2;Q9HAW4-3;Q9HAW4;E7ESG2 Q9HAW4-2 CLSPN Claspin 1 0 LSEPSLPIEDS(0.996)QDLY(0.001)NAS(0.002)PEPK 76.55 0.00064138 0 1602.8 2649 2195.1 1685.8 1648.6 2807.3 2054.5 854.05 3015.3 1874.9 TRUE FALSE FALSE 1475.936689 2877.967756 2276.452337 1678.824606 1628.941522 2225.034335 2112.143741 1114.445913 2684.529134 1940.052635 0.760771467 1.483448286 1.173397203 0.86535003 0.839637797 1.146893798 1.088704349 0.574441071 1.383740361 1 10.92188008 LSEPSLPIEDSQDLY(ph)NASPEPK ddPTM_HeLa_Curcumin_4h_R1 2 LSEPSLPIEDSQDLYNASPEPK 22 0 Q9HAW4-2;Q9HAW4-3;Q9HAW4;E7ESG2 Q9HAW4-2 CLSPN Claspin 1 0 LSEPSLPIEDS(0.001)QDLY(0.978)NAS(0.021)PEPK;LSEPSLPIEDS(0.101)QDLY(0.791)NAS(0.108)PEPK ; 91.889 0.0013562 16843300 9854.3 7309.5 8273.7 8327.6 8475.1 9046.7 6638.1 4567.5 9594.2 7439.4 TRUE FALSE FALSE 9074.321757 7941.30061 8580.3306 8293.142598 8374.039968 7170.312443 6824.34722 5960.109724 8541.740264 7697.918596 1.17880199 1.0316166 1.114629947 1.07732272 1.087831712 0.931461193 0.886518497 0.774249513 1.10961686 1 12.9102527 -4.848024477 1.358033592 1.085657358 0.775582839 0.822718074 0.04922299 0.238364889 0.703986262 0.01026262 0.075398027 1.42E-05 4.848024477 -0.310074519 TMIIS(ph)PERLDPFADGGKT(ph)PDPK ddPTM_HeLa_Curcumin_4h_R1 1 TMIISPERLDPFADGGKTPDPK 22 2 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 2 0 T(0.002)MIIS(0.998)PERLDPFADGGKT(1)PDPK 72.231 0.010212 58224000 3355.7 2914 3241 4112.5 2962.1 4636 2714.5 1207.1 4158.4 3604.2 TRUE FALSE FALSE 3090.092804 3165.873175 3361.114311 4095.483565 2926.778892 3674.441342 2790.661564 1575.139233 3702.233924 3729.445682 0.828566245 0.848885718 0.901236966 1.098148067 0.784775847 0.985251336 0.748277841 0.422352105 0.992703538 1 11.8647455 -4.34749061 2.485801576 0.917965599 0.360132571 0.744549579 0.090707309 0.16787841 1.452942953 0.013183499 0.181118753 4.49E-05 4.34749061 -0.557833029 down LSFASETPLEKEPHS(ph)PADQPEQQAESTLTSAETR ddPTM_HeLa_Curcumin_4h_R1 1 LSFASETPLEKEPHSPADQPEQQAESTLTSAETR 34 1 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2 H3BSS6 ZNF106 Zinc finger protein 106 1 0 LSFAS(0.009)ET(0.035)PLEKEPHS(0.956)PADQPEQQAESTLTSAETR 89.751 4.32E-09 26972000 1533.3 1225 1284.2 1396.5 1504.6 1558.4 1285.1 639.22 1793.6 1306.8 TRUE FALSE FALSE 1411.937687 1330.883542 1331.793582 1390.721653 1486.658628 1235.170273 1321.156447 834.1152354 1596.846567 1352.211203 1.044169494 0.984227567 0.984900568 1.028479612 1.09942783 0.913444786 0.977034094 0.616852777 1.180915055 1 10.40110479 -3.873521511 1.505835728 1.018244666 4.98E-20 0.760946229 0.068758287 0.756756146 0.719163158 0.006253435 1.525079576 0.000133807 3.873521511 -1.018244666 LSGEHS(ph)ESSTPRPR ddPTM_HeLa_Curcumin_4h_R1 2 LSGEHSESSTPRPR 14 1 Q7Z3K3-5;Q7Z3K3-7;Q7Z3K3-2;Q7Z3K3-3;Q7Z3K3-6;Q7Z3K3 Q7Z3K3-5 POGZ Pogo transposable element with ZNF domain 1 0 LSGEHS(0.998)ES(0.001)STPRPR;LS(0.005)GEHS(0.993)ES(0.001)STPRPR ; 80.719 0.0080629 32919000 2292.6 1787.11 1719.33 1810.53 2933.9 4141.3 2096.6 1609.75 3236.1 2206.55 TRUE FALSE FALSE 2111.138291 1941.579825 1783.049882 1803.038507 2898.915159 3282.347698 2155.424953 2100.555365 2881.107926 2283.227448 0.924628991 0.850366365 0.780933973 0.789688521 1.269656758 1.437591205 0.944025509 0.919993917 1.261857608 1 11.15685887 -5.75858296 24.9986406 0.927866433 1.149672769 0.225537993 0.188623662 75.06296664 656919.2809 0.024549632 0.047423956 1.74E-06 5.75858296 0.221806336 LSGEMPPASPS(ph)FPR ddPTM_HeLa_Curcumin_4h_R1 1 LSGEMPPASPSFPR 14 0 Q96JM7-2;Q96JM7 Q96JM7-2 L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 1 0 LSGEMPPAS(0.226)PS(0.774)FPR 87.863 0.013906 29221000 3813.1 3122.8 3142.1 2980.4 3422.7 4133 3562.7 2623.5 3734.8 3174.1 TRUE FALSE FALSE 3511.289111 3392.720917 3258.54899 2968.067895 3381.886538 3275.769211 3662.659773 3423.393073 3325.101784 3284.399739 1.069080925 1.03298051 0.992129232 0.903686558 1.02968177 0.997372266 1.115168696 1.04231925 1.012392537 1 11.68141401 -4.770181541 24.9994114 1.019097959 1.078743978 0.258691911 0.045150163 214.3605089 613001.6289 0.007116829 0.021845415 1.70E-05 4.770181541 0.05964602 LSGFS(ph)FK ddPTM_HeLa_Curcumin_4h_R1 1 LSGFSFK 7 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 LSGFS(1)FK 104.2 0.017634 936930000 7264.6 5169.9 6620.3 6793.9 7485.1 8347.4 8985.7 4325.5 5749.3 5767.3 TRUE FALSE FALSE 6689.599244 5616.763119 6865.654142 6765.788642 7395.845071 6616.055145 9237.814558 5644.325038 5118.616174 5967.713246 1.120965262 0.941191858 1.150466495 1.133732196 1.239309727 1.108641597 1.547965557 0.945810364 0.857718185 1 12.5429625 -6.135053403 1.420325041 1.050628454 1.23173057 0.23838231 0.161336251 0.435306087 1.727885515 0.022424636 0.045001859 7.33E-07 6.135053403 0.181102117 LSGINEIPRPFS(ph)PPVT(ph)SNTSPPPAAPLAR ddPTM_HeLa_Curcumin_4h_R1 2 LSGINEIPRPFSPPVTSNTSPPPAAPLAR 29 1 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 2 0 LSGINEIPRPFS(0.889)PPVT(0.278)S(0.278)NT(0.278)S(0.278)PPPAAPLAR;LS(0.004)GINEIPRPFS(0.961)PPVT(0.36)S(0.321)NT(0.258)S(0.096)PPPAAPLAR ; 54.304 0.0063553 72184000 4138.2 3263.3 3388.5 4070.8 3215.4 4430.9 2675.4 2046.73 4795.2 3772.8 TRUE FALSE FALSE 3810.657103 3545.365111 3514.080791 4053.956108 3177.058455 3511.881393 2750.464524 2670.768555 4269.178557 3903.904519 0.97611432 0.908158766 0.900145168 1.038436286 0.813815614 0.899581784 0.704541955 0.68412753 1.093566335 1 11.93070205 -3.255409059 0.406315691 0.991539101 4.78E-16 0.737221346 0.065785473 3.330619113 0.203744405 0.013084549 1.914874115 0.000555381 3.255409059 -0.991539101 LSGINEIPRPFS(ph)PPVTSNTSPPPAAPLAR ddPTM_HeLa_Curcumin_4h_R1 2 LSGINEIPRPFSPPVTSNTSPPPAAPLAR 29 1 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 0 LS(0.001)GINEIPRPFS(0.668)PPVT(0.063)S(0.179)NT(0.063)S(0.027)PPPAAPLAR;LSGINEIPRPFS(0.956)PPVT(0.029)S(0.011)NT(0.003)S(0.001)PPPAAPLAR ; 90.601 7.70E-08 213210000 2035.18 1483.44 1380.25 1737.99 1859.01 2443.4 1066.64 1161.11 2039.34 1598.43 TRUE FALSE FALSE 1874.093355 1611.661944 1431.403279 1730.798658 1836.84252 1936.611297 1096.567048 1515.127094 1815.629504 1653.975324 1.13308423 0.974417164 0.865432065 1.046447691 1.110562228 1.170882824 0.662988759 0.916051813 1.097736755 1 10.691722 -4.762414383 24.99990861 1.051707165 0.789520281 0.515651704 0.100896854 14.55544613 373268.3999 0.014465079 0.047387166 1.73E-05 4.762414383 -0.262186883 LSGLAAPDYTRLS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 2 LSGLAAPDYTRLSPAK 16 1 Q8TEK3;Q8TEK3-1 Q8TEK3 DOT1L "Histone-lysine N-methyltransferase, H3 lysine-79 specific" 1 0 LSGLAAPDYT(0.062)RLS(0.938)PAK;LSGLAAPDYTRLS(1)PAK ; 124.29 0.0064363 50288000 4819.7 3302.6 3824 4279.6 4420.8 5556.9 5026.5 2437.2 4852.6 4051.2 TRUE FALSE FALSE 4438.215659 3588.062028 3965.720804 4261.892149 4368.084847 4404.336301 5167.530062 3180.291061 4320.281921 4191.978898 1.058739981 0.855935136 0.946025946 1.016677863 1.042010218 1.050658032 1.232718529 0.758661038 1.030606791 1 12.03341574 -4.222500696 23.96137511 1.023345063 0.758659804 0.442777118 0.089906033 10548.97289 6491218.582 0.012222519 4.822041621 5.99E-05 4.222500696 -0.264685259 LSILYPATTGR ddPTM_HeLa_Curcumin_4h_R1 2 LSILYPATTGR 11 0 P30041 P30041 PRDX6 Peroxiredoxin-6 0 0 ; ; 154.85 2.36E-07 10075500 2553.4 1940.59 2243.85 1952.2 1932.08 2389.47 1971.38 2334.87 2416.8 2054.32 FALSE FALSE TRUE 2351.295696 2108.325952 2327.009055 1944.122314 1909.041208 1893.866987 2026.691617 3046.761115 2151.683087 2125.707467 1.106123835 0.991823186 1.094698631 0.914576603 0.898073341 0.890934908 0.953419814 1.433292756 1.012219753 1 11.05372736 -4.256205362 24.84977537 1.015515251 1.433292947 0.746353479 0.076583386 245.5010361 1165535.391 0.012634994 0.143400682 5.54E-05 4.256205362 0.417777696 LSKS(ph)NIDISSGLEDEEPKRPLPR ddPTM_HeLa_Curcumin_4h_R1 1 LSKSNIDISSGLEDEEPKRPLPR 23 3 Q9BZ71;Q9BZ71-3 Q9BZ71 PITPNM3 Membrane-associated phosphatidylinositol transfer protein 3 1 0 LS(0.075)KS(0.922)NIDIS(0.002)S(0.001)GLEDEEPKRPLPR 49.066 0.014729 32662000 1237.8 587.83 859.55 1068 977.46 1133.3 652.07 722.44 1111.2 892.11 TRUE FALSE FALSE 1139.826824 638.6394059 891.4056791 1063.580899 965.8044279 898.2408051 670.3653292 942.7086303 989.3041401 923.1107561 1.234767135 0.691833999 0.965654092 1.152170411 1.046249783 0.973058541 0.72620249 1.021230252 1.071706871 1 9.850359945 -5.309774592 0.524906739 1.086969371 0.844532933 0.016299165 0.158835718 2.658709838 0.931970056 0.03972986 0.326462831 4.90E-06 5.309774592 -0.242436438 LSKS(ph)QGGEEEGPLSDK ddPTM_HeLa_Curcumin_4h_R1 1 LSKSQGGEEEGPLSDK 16 1 E9PR76;E9PSH4;Q9H063 E9PR76 MAF1 Repressor of RNA polymerase III transcription MAF1 homolog 1 0 LS(0.014)KS(0.986)QGGEEEGPLSDK 136.66 0.0040047 12218000 1824.3 1800.8 1893.2 1310.7 1588.4 1910.6 1224.2 892.19 2391.5 1662.1 TRUE FALSE FALSE 1679.90473 1956.453128 1963.363657 1305.276671 1569.459367 1514.320023 1258.547757 1164.214624 2129.158433 1719.857851 0.976769521 1.137566762 1.141584844 0.758944508 0.912551794 0.880491386 0.73177429 0.676924912 1.237985123 1 10.74807361 -6.246165441 24.91988554 1.012656205 0.800382109 0.612369597 0.111853358 448.9085352 732407.6622 0.014070083 0.02327402 5.67E-07 6.246165441 -0.212274096 LSLDER ddPTM_HeLa_Curcumin_4h_R1 1 LSLDER 6 0 P62310 P62310 LSM3 U6 snRNA-associated Sm-like protein LSm3 0 0 114.6 0.0064654 0 8400.8 7013.8 7817.3 7004.3 7401 10139 8226 7705.9 7910.3 6884.2 FALSE FALSE TRUE 7735.867816 7620.041619 8107.016015 6975.318062 7312.747909 8036.05711 8456.799421 10055.39344 7042.559881 7123.425438 1.085975825 1.069715923 1.138078314 0.979208405 1.026577448 1.128116968 1.187181574 1.411595239 0.988647939 1 12.79835544 -4.146636468 1.192320257 1.045893389 1.651645689 0.846531119 0.048044159 0.552784839 0.541860548 0.007517303 0.440482639 7.13E-05 4.146636468 0.6057523 LSLEGDHS(ph)TPPSAYGSVK ddPTM_HeLa_Curcumin_4h_R1 4 LSLEGDHSTPPSAYGSVK 18 0 H0YMW4;P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4;P07355-2 H0YMW4;P07355;P07355-2 ANXA2;ANXA2P2 Annexin;Annexin A2;Putative annexin A2-like protein 1 0 LSLEGDHS(0.99)T(0.01)PPSAYGSVK;LSLEGDHS(0.79)T(0.21)PPSAYGSVK;LSLEGDHS(0.999)T(0.001)PPSAYGSVK;LSLEGDHS(0.934)T(0.066)PPSAYGSVK ;;; 303.44 1.15E-96 355035000 11972.79 9354.2 9474.86 10059.87 15043.9 28472.6 21624.5 11937.2 14550.2 8908.83 TRUE FALSE FALSE 11025.13104 10162.73537 9826.006647 10018.24492 14864.51132 22567.06181 22231.22527 15576.79733 12954.07946 9218.411179 1.195990374 1.102438931 1.065911083 1.086764815 1.612480831 2.448042441 2.411611376 1.689748594 1.405239928 1 13.1703024 -5.529303034 3.252792973 1.093738162 2.200456048 0.811669958 0.223277324 0.061275367 1.34367758 0.02877737 0.064750684 2.96E-06 5.529303034 1.106717886 LSLEGDHSTPPSAY(ph)GSVK ddPTM_HeLa_Curcumin_4h_R1 1 LSLEGDHSTPPSAYGSVK 18 0 H0YMW4;P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4;P07355-2 H0YMW4;P07355;P07355-2 ANXA2;ANXA2P2 Annexin;Annexin A2;Putative annexin A2-like protein 1 0 LSLEGDHSTPPS(0.012)AY(0.694)GS(0.294)VK 99.392 0.00070064 0 1828.7 2053.4 1835.4 1494.9 2562.3 6510.9 1920.6 1267 4246.8 1629.4 TRUE FALSE FALSE 1683.956465 2230.886746 1903.421539 1488.7145 2531.746246 5160.465947 1974.486867 1653.302467 3780.936665 1686.021529 0.998775186 1.323166228 1.128942606 0.882974787 1.501609679 3.0607355 1.171092322 0.980593924 2.242519802 1 10.71940724 -5.587823256 6.088843635 1.033135341 1.775291296 0.030042204 0.650737143 0.185907536 12.91103819 0.0746577 0.151085833 2.58E-06 5.587823256 0.742155955 LSLEGDHSTPPSAYGS(ph)VK ddPTM_HeLa_Curcumin_4h_R1 1 LSLEGDHSTPPSAYGSVK 18 0 H0YMW4;P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4;P07355-2 H0YMW4;P07355;P07355-2 ANXA2;ANXA2P2 Annexin;Annexin A2;Putative annexin A2-like protein 1 0 LSLEGDHST(0.002)PPS(0.037)AYGS(0.96)VK 101.6 0.00055664 0 3016.3 2408.7 2777.5 3077.6 4091.2 6278.5 4570.3 3451.6 3368.6 2772.9 TRUE FALSE FALSE 2777.556672 2616.897295 2880.436593 3064.865707 4042.415112 4976.268327 4698.530318 4503.976951 2999.073008 2869.258069 0.968040032 0.91204668 1.003895964 1.068173595 1.408871219 1.734339752 1.637541903 1.569735745 1.045243382 1 11.48646202 -5.663834981 2.382674178 0.980162831 1.646155123 0.969527042 0.052418898 0.029792028 0.342801914 0.007196059 0.016061789 2.17E-06 5.663834981 0.665992292 LSLEGDHSTPPSAYGSVK ddPTM_HeLa_Curcumin_4h_R1 3 LSLEGDHSTPPSAYGSVK 18 0 H0YMW4;P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;H0YKL9;H0YKV8;H0YMD9;H0YNB8;H0YKN4;P07355-2 H0YMW4;P07355;P07355-2 ANXA2;ANXA2P2 Annexin;Annexin A2;Putative annexin A2-like protein 0 0 ;; ;; 108.96 0.00043129 26183400 6987.9 6025.3 4603.18 5029.4 12838.9 27133 10138.7 8441.7 13304.5 5490.4 FALSE FALSE TRUE 6434.800341 6546.100084 4773.7779 5008.589675 12685.8045 21505.30995 10423.16464 11015.53547 11845.02964 5681.190991 1.132649888 1.152240805 0.840277665 0.8816091 2.232948078 3.785352399 1.834679498 1.938948274 2.084955365 1 12.47197769 -5.690460765 5.156221846 1.0418354 2.530372752 0.510068775 0.601127522 0.090908491 4.464810643 0.071047446 0.14321495 2.04E-06 5.690460765 1.488537352 LSLFSDGDS(ph)SESEDTLSSSER ddPTM_HeLa_Curcumin_4h_R1 2 LSLFSDGDSSESEDTLSSSER 21 0 M0QZ79;M0QXD7;M0R025;M0QYG0;M0QYA8;Q8IV63-2;Q8IV63 M0QZ79 VRK3 Inactive serine/threonine-protein kinase VRK3 1 0 LSLFSDGDS(0.623)S(0.37)ES(0.007)EDTLSSSER;LSLFSDGDS(0.492)S(0.492)ES(0.016)EDTLSSSER ; 170.53 1.35E-08 6949300 2190.91 1793.92 2039.31 1897.24 1963.45 2637.3 1602.74 1501.66 2427.9 1737.09 TRUE FALSE FALSE 2017.497162 1948.978451 2114.888623 1889.389724 1940.037141 2090.294252 1647.708571 1959.509221 2161.565444 1797.453748 1.122419514 1.08429964 1.176602527 1.051147895 1.079325208 1.162919632 0.916690386 1.090158355 1.202570829 1 10.81173893 -3.910199271 21.56519703 1.067381467 3.058566147 0 0.083846647 5762.492142 1710101.853 0.010276366 132794.8887 0.00012297 3.910199271 1.99118468 LSLT(ph)RSPVSPLAAQGIPLPAQLTK ddPTM_HeLa_Curcumin_4h_R1 1 LSLTRSPVSPLAAQGIPLPAQLTK 24 1 K7EIF1;K7EPF0;K7EQS3;K7EM48;K7EN63;Q96SI1-2;Q96SI1 K7EIF1 KCTD15 BTB/POZ domain-containing protein KCTD15 1 0 LS(0.096)LT(0.336)RS(0.336)PVS(0.232)PLAAQGIPLPAQLTK 108.78 2.40E-06 13127000 2005.5 1013.5 1227.1 1457.2 1277.2 2231.2 1232.2 674.41 2085.2 1829.3 TRUE FALSE FALSE 1846.762559 1101.102424 1272.577405 1451.170493 1261.970224 1768.423969 1266.772216 880.0345044 1856.458777 1892.868039 0.975642528 0.58171114 0.672301174 0.766651696 0.666697413 0.934256342 0.669234299 0.464921213 0.980765029 1 10.88635812 -7.278067532 22.91032624 0.988497907 0.69140235 0.601237933 0.113925576 132.3938397 182412.1675 0.019193012 0.021991334 5.27E-08 7.278067532 -0.297095557 LSLTSDPEEGDPLALGPES(ph)PGEPQPPQLK ddPTM_HeLa_Curcumin_4h_R1 3 LSLTSDPEEGDPLALGPESPGEPQPPQLK 29 0 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 0 LSLTS(0.001)DPEEGDPLALGPES(0.999)PGEPQPPQLK;LSLTSDPEEGDPLALGPES(1)PGEPQPPQLK;LS(0.141)LT(0.125)S(0.336)DPEEGDPLALGPES(0.398)PGEPQPPQLK ;; 79.36 4.47E-06 10118500 4653.55 4013.73 3784.25 4324.16 4487.44 4961.2 4285.19 6021.58 4763.56 4184.47 TRUE FALSE FALSE 4285.216607 4360.658936 3924.497634 4306.267772 4433.930209 3932.191196 4405.420898 7857.532022 4241.009386 4329.880021 0.989684838 1.007108492 0.906375607 0.994546674 1.024030732 0.908152461 1.017446414 1.814722806 0.979475035 1 12.08011133 -4.262121681 5.613365673 0.986124584 1.84265891 0.977148402 0.0382817 0.013375739 1.701914658 0.004966139 0.043751792 5.47E-05 4.262121681 0.856534326 LSLVIRS(ph)PSLLQSGAK ddPTM_HeLa_Curcumin_4h_R1 1 LSLVIRSPSLLQSGAK 16 1 Q9BQG0;Q9BQG0-2;I3L1L3;I3L2H8 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 0 LS(0.001)LVIRS(0.969)PS(0.028)LLQS(0.002)GAK 69.07 0.011545 28591000 2799.5 2179.1 2494.1 2594.4 2414.7 3753.4 2640.9 1273.2 2736.1 2196.3 TRUE FALSE FALSE 2577.916621 2367.451694 2586.53354 2583.66506 2385.90628 2974.90253 2714.996546 1661.392819 2435.956675 2272.621262 1.134336224 1.041727337 1.138127846 1.136865656 1.049847733 1.309018172 1.194654205 0.73104694 1.071870935 1 11.15014156 -9.402568679 0.983954616 0.996256041 1.105236211 0.007554007 0.142901438 1.354918922 2.2130416 0.109546856 0.024279959 3.96E-10 9.402568679 0.108980171 LSLYIQMS(ph)S(ph)VY(ph)S(ph)AK ddPTM_HeLa_Curcumin_4h_R1 1 LSLYIQMSSVYSAK 14 0 Q96LM1 Q96LM1 LINC00615 Putative uncharacterized protein encoded by LINC00615 4 0 LS(0.067)LY(0.023)IQMS(0.928)S(0.985)VY(0.999)S(0.998)AK 46.408 0.0095394 0 156.43 0 59.988 138.74 52.418 244.87 135.4 120.68 195.58 0 TRUE FALSE FALSE 144.0484004 0 62.21120805 138.1659306 51.79294959 194.0812017 139.1989596 157.4747765 174.1253633 0 0 LSMEDSKS(ph)PPPK ddPTM_HeLa_Curcumin_4h_R1 1 LSMEDSKSPPPK 12 1 Q9NQG5 Q9NQG5 RPRD1B Regulation of nuclear pre-mRNA domain-containing protein 1B 1 0 LSMEDS(0.033)KS(0.967)PPPK 149.69 0.0054796 23537000 2785.1 2303.9 2384.1 2240.3 2666.4 3300.5 2546.3 2009.2 2493.2 2538.9 TRUE FALSE FALSE 2564.656396 2503.03885 2472.456843 2231.030232 2634.604921 2615.939096 2617.742325 2621.795831 2219.702198 2627.126586 0.976221096 0.952766747 0.941125889 0.849228295 1.002846584 0.995741549 0.996427937 0.99797088 0.844916347 1 11.35927 LSMEDSKS(ph)PPPKATEEK ddPTM_HeLa_Curcumin_4h_R1 2 LSMEDSKSPPPKATEEK 17 2 Q9NQG5 Q9NQG5 RPRD1B Regulation of nuclear pre-mRNA domain-containing protein 1B 1 0 LS(0.019)MEDS(0.419)KS(0.562)PPPKATEEK;LS(0.053)MEDS(0.176)KS(0.771)PPPKAT(0.001)EEK ; 69.763 0.014328 211505000 9070.2 7983.5 7648.9 8844.3 7452.6 11215.1 8835.7 6096.2 9981.3 8710.9 TRUE FALSE FALSE 8352.284099 8673.558166 7932.374963 8807.70463 7363.732612 8888.96184 9083.605962 7954.903317 8886.376362 9013.603127 0.926631002 0.962274248 0.880044845 0.977156916 0.816957715 0.986171869 1.007766354 0.882544217 0.985885027 1 13.13788821 -9.222829223 0.72213922 1.005433645 0.930719425 0.172302407 0.054931041 1.124665171 0.936942766 0.050892294 0.010789529 5.99E-10 9.222829223 -0.074714221 LSMEDSKS(ph)PPPKATEEKK ddPTM_HeLa_Curcumin_4h_R1 1 LSMEDSKSPPPKATEEKK 18 3 Q9NQG5 Q9NQG5 RPRD1B Regulation of nuclear pre-mRNA domain-containing protein 1B 1 0 LS(0.012)MEDS(0.033)KS(0.953)PPPKAT(0.002)EEKK 52.99 0.020217 55168000 4954.1 3426.1 4058.4 4431.7 3690.5 5392 3922.4 3437.3 5966.3 5950.4 TRUE FALSE FALSE 4561.977757 3722.236818 4208.807874 4413.3628 3646.493198 4273.63842 4032.451987 4485.316947 5311.811817 6157.175957 0.740920479 0.604536372 0.683561409 0.716783608 0.592234691 0.694090676 0.654919076 0.728469834 0.862702618 1 12.58805308 -8.669360073 0.606413704 1.008474305 0.66338945 0.730600882 0.060208793 0.195889828 0.139691573 0.033456216 0.01170168 2.14E-09 8.669360073 -0.345084856 LSMWDRPDDLIGR ddPTM_HeLa_Curcumin_4h_R1 2 LSMWDRPDDLIGR 13 1 O14776;O14776-2;G3V220 O14776 TCERG1 Transcription elongation regulator 1 0 0 ; ; 110.15 0.0034637 28620000 4879 3763.2 4132.3 4453.3 3853.1 5165.3 4448.1 4391.3 5036.5 4016.6 FALSE FALSE TRUE 4492.822002 4088.47424 4285.446673 4434.873425 3807.154299 4093.958555 4572.901715 5730.187155 4484.008551 4156.176551 1.080998833 0.983710434 1.031103135 1.067056072 0.916023237 0.985029992 1.100266473 1.378716011 1.078878266 1 12.02104122 -4.288625839 3.010857085 1.025281873 1.424942817 0.829151699 0.049012528 0.107622504 1.471032957 0.007178228 0.099287023 5.14E-05 4.288625839 0.399660943 LSNGS(ph)FSAPSLTNSR ddPTM_HeLa_Curcumin_4h_R1 1 LSNGSFSAPSLTNSR 15 0 O94806;O94806-2 O94806 PRKD3 Serine/threonine-protein kinase D3 1 0 LS(0.231)NGS(0.649)FS(0.003)APS(0.096)LT(0.021)NSR 164.58 0.00025041 15320000 883 842.15 628.63 772.21 730.62 669.06 467.8 351.64 764.44 820.79 TRUE FALSE FALSE 813.1096183 914.9416935 651.9275808 769.0147996 721.9078337 530.2894141 480.925209 458.8534172 680.5828445 849.3123914 0.95737402 1.077273454 0.767594571 0.905455763 0.849990935 0.624374988 0.566252434 0.540264597 0.80133394 1 9.730151489 -5.208212782 0.689201991 0.984925078 0.447366555 0.730082367 0.091245537 0.301160889 0.193378162 0.012223977 0.099165698 6.19E-06 5.208212782 -0.537558523 LSNLALVKPEK ddPTM_HeLa_Curcumin_4h_R1 1 LSNLALVKPEK 11 1 O14737;K7EQA1;O14737-2 O14737 PDCD5 Programmed cell death protein 5 0 0 89.301 0.0029419 0 1560.3 1806.6 1828.2 1983.7 1705.4 2315.2 1692.3 1868.9 2022.4 1458.4 FALSE FALSE TRUE 1436.800609 1962.754454 1895.9547 1975.491975 1685.064219 1835.001422 1739.781383 2438.719007 1800.54778 1509.079291 0.952104119 1.300630434 1.256365196 1.309071025 1.116617416 1.215974159 1.152876057 1.61603106 1.193143256 1 10.5594529 -7.262386779 24.9943023 0.977382496 1.267446154 0.315781294 0.145153813 45.78188659 1207812.861 0.020311219 0.023950372 5.47E-08 7.262386779 0.290063658 LSPEELLLR ddPTM_HeLa_Curcumin_4h_R1 1 LSPEELLLR 9 0 P13797;A0A0A0MSQ0;P13797-3;P13797-2;Q14651;C9JAM8;P13796 P13797 PLS3;PLS1;LCP1 Plastin-3;Plastin-1;Plastin-2 0 0 103.83 0.0056342 760010 212.37 113.37 163.4 223.56 225.58 220.1 140.6 114.28 155.6 192.45 FALSE FALSE TRUE 195.5606904 123.1691976 169.4557477 222.634968 222.8901058 174.448779 144.5448576 149.1234459 138.5310693 199.1376232 0.982037886 0.618512944 0.850947928 1.117995507 1.119276721 0.876021197 0.725854087 0.748846167 0.69565493 1 7.637622006 -4.924156956 4.275197649 0.969871524 0.740431271 0.082618136 0.160975209 0.200365469 7.005824814 0.020136691 0.064789684 1.19E-05 4.924156956 -0.229440253 LSPGESAY(ph)QK ddPTM_HeLa_Curcumin_4h_R1 1 LSPGESAYQK 10 0 A0A0G2JHC2;Q6NYC8;Q6NYC8-2 A0A0G2JHC2 PPP1R18 Phostensin 1 0 LSPGES(0.008)AY(0.992)QK 106.88 0.0055447 0 1690.5 1844.7 1761.9 1549 1757.1 2164.8 1506.3 1308 2457.5 2034.3 TRUE FALSE FALSE 1556.695141 2004.147648 1827.197564 1542.590648 1736.14773 1715.796078 1548.562724 1706.803179 2187.918398 2104.991774 0.739525522 0.952092865 0.868030739 0.732825025 0.824776492 0.81510821 0.735662126 0.810836033 1.039395225 1 11.03959888 -9.458283731 1.026432554 1.007664519 0.805088464 0.616371329 0.065396575 0.355466504 0.627309494 0.055672979 0.011815452 3.48E-10 9.458283731 -0.202576054 LSPGS(ph)YPTVIQQQNATSQR ddPTM_HeLa_Curcumin_4h_R1 1 LSPGSYPTVIQQQNATSQR 19 0 Q13469-5;Q13469-3;Q13469-4;Q13469-2;Q13469 Q13469-5 NFATC2 "Nuclear factor of activated T-cells, cytoplasmic 2" 1 0 LS(0.009)PGS(0.885)Y(0.102)PT(0.004)VIQQQNATSQR 142.4 0.00017854 6137200 1646.5 1915.1 1672.6 1934.4 1664.5 1949.1 1431.3 678.25 1706.7 1522.5 TRUE FALSE FALSE 1516.177788 2080.63271 1734.588027 1926.395965 1644.651925 1544.834689 1471.458426 885.0453027 1519.47928 1575.406762 0.962404012 1.320695557 1.101041375 1.222792749 1.043953831 0.980594172 0.934018097 0.561788437 0.964499656 1 10.62150866 -4.090677126 1.648341592 1.0374962 0.222071851 0.633452557 0.115384267 0.923317776 1.697271647 0.018407367 1.359933602 8.12E-05 4.090677126 -0.815424349 LGS(ph)PLAVDEALRR ddPTM_HeLa_Curcumin_4h_R1 1 LGSPLAVDEALRR 13 1 Q7RTP6 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 0 LGS(1)PLAVDEALRR 141.82 0.00042813 21138000 3042.3 2555.8 2412 2806.1 2428.3 3374.7 3201.8 5699.4 3069 2594 TRUE FALSE FALSE 2801.498745 2776.711964 2501.390842 2794.489102 2399.344108 2674.749179 3291.633891 7437.120823 2732.338378 2684.141307 1.043722526 1.034487997 0.931914738 1.041111023 0.893896347 0.996500882 1.226326603 2.770763523 1.017956235 1 11.39024491 -4.254221721 3.251746905 1.007995069 3.034743273 0.99190161 0.047830793 0.021580496 0.356371594 0.007049873 0.110749448 5.57E-05 4.254221721 2.026748204 up TPAAAAAMNLAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 TPAAAAAMNLASPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 TPAAAAAMNLAS(1)PR;TPAAAAAMNLAS(1)PR ; 139.34 0.00078622 85922000 907.95 751.51 789.27 671.42 943.34 976.55 981.18 1741.31 769.7 751.14 TRUE FALSE FALSE 836.0847994 816.4671757 818.5210405 668.6418419 932.0912866 774.002522 1008.70927 2272.227403 685.2658357 777.2420591 1.075707097 1.050467054 1.053109557 0.860274909 1.199229089 0.99583201 1.297805823 2.923448849 0.881663348 1 9.602220162 -4.253894512 3.09604756 1.036603691 3.23364957 0.973585391 0.09373481 0.032333239 0.458499096 0.010428762 0.174307171 5.57E-05 4.253894512 2.19704588 up LSPPVASGGIPHQS(ph)PPTK ddPTM_HeLa_Curcumin_4h_R1 1 LSPPVASGGIPHQSPPTK 18 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 0 LSPPVASGGIPHQS(0.965)PPT(0.035)K 83.727 0.0024036 35974000 2831.9 2282.8 2792.3 2465.8 3340.5 3773.1 2468.2 1125 3290.6 2518.8 TRUE FALSE FALSE 2607.752127 2480.11506 2895.785094 2455.597173 3300.666719 2990.516528 2537.451049 1468.007321 2929.629413 2606.328113 1.000546368 0.951574381 1.111059302 0.94216732 1.26640491 1.147406005 0.973573142 0.563247319 1.124044743 1 11.347803 -4.272627844 4.177776518 1.02834809 0.530224963 0.678032172 0.101014239 0.09386301 3.629584039 0.013581184 0.136977653 5.34E-05 4.272627844 -0.498123127 LSPPYSS(ph)PQEFAQDVGR ddPTM_HeLa_Curcumin_4h_R1 2 LSPPYSSPQEFAQDVGR 17 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 0 LSPPYS(0.404)S(0.596)PQEFAQDVGR;LSPPYS(0.044)S(0.956)PQEFAQDVGR ; 140.68 0.00034205 21564900 1831.78 1395.9 1938.61 1832.54 1721.62 2357.63 1693.47 2018.11 1906.6 1705.08 TRUE FALSE FALSE 1686.79268 1516.555376 2010.456592 1824.957435 1701.090806 1868.630962 1740.98421 2633.422449 1697.45075 1764.331403 0.956052064 0.859563783 1.139500543 1.034362043 0.964156055 1.059115628 0.986767116 1.492589456 0.962092919 1 10.78490586 -4.261215436 24.41908895 0.989933839 1.492589645 0.819633213 0.06987523 3.788533479 412730.3957 0.009303573 0.072520347 5.48E-05 4.261215436 0.502655806 AQIS(ph)SPNLR ddPTM_HeLa_Curcumin_4h_R1 1 AQISSPNLR 9 0 H0Y507;Q5TCZ1-2;Q5TCZ1-3;Q5TCZ1 H0Y507 SH3PXD2A SH3 and PX domain-containing protein 2A 1 0 AQIS(0.5)S(0.5)PNLR 130.41 0.00089009 0 4087 2962.2 2919.4 3084.7 3433.1 3760.7 2326.2 370 3614.4 2941.8 TRUE FALSE FALSE 3763.509637 3218.239369 3027.595532 3071.936329 3392.162525 2980.688428 2391.466911 482.8112967 3217.909363 3044.027331 1.236358688 1.057230773 0.994601954 1.009168445 1.114366645 0.9791924 0.785625966 0.158609383 1.057122362 1 11.5717656 -4.34714747 1.787891312 1.091287835 5.06E-21 0.929762331 0.074630998 0.173083344 0.629593826 0.014564653 0.299353095 4.50E-05 4.34714747 -1.091287835 down LSPS(ph)PSSR ddPTM_HeLa_Curcumin_4h_R1 4 LSPSPSSR 8 0 P20700;Q03252 P20700;Q03252 LMNB1;LMNB2 Lamin-B1;Lamin-B2 1 0 LS(0.004)PS(0.949)PS(0.047)S(0.001)R;LS(0.006)PS(0.95)PS(0.043)SR;LSPS(0.964)PS(0.035)SR;LS(0.004)PS(0.953)PS(0.043)SR ;;; 145.9 0.0023941 5773620000 19238.2 15539.8 16498 17442 16504.7 17813.1 12687.6 11730.4 17920.9 14555.6 TRUE FALSE FALSE 17715.47617 16882.99107 17109.43039 17369.82963 16307.89223 14118.46226 13043.57991 15306.94496 15955.02211 15061.40602 1.176216626 1.120943891 1.135978299 1.153267471 1.082760282 0.937393378 0.866026711 1.016302525 1.059331518 1 13.87856883 -5.273063744 5.146494137 1.097691822 0.931283741 0.624736377 0.05815062 0.115007532 9.777296124 0.010974096 0.026478193 5.33E-06 5.273063744 -0.166408081 LSPS(ph)PTSQR ddPTM_HeLa_Curcumin_4h_R1 5 LSPSPTSQR 9 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 LS(0.003)PS(0.958)PT(0.037)S(0.002)QR;LS(0.077)PS(0.911)PT(0.012)SQR;LS(0.003)PS(0.981)PT(0.016)SQR;LS(0.08)PS(0.92)PT(0.001)SQR;LS(0.208)PS(0.792)PTSQR ;;;; 136.81 0.0028492 12206434400 15241.8 13503.1 14644.5 14195.9 14493.7 16092.8 13205.6 12492.6 14914 12976.6 TRUE FALSE FALSE 14035.39545 14670.2478 15187.23805 14137.16113 14320.87209 12754.97188 13576.11359 16301.53623 13277.97151 13427.53588 1.045269629 1.092549513 1.131051757 1.052848508 1.066530167 0.949911584 1.011065151 1.214037808 0.988861369 1 13.71290696 -8.262892497 1.039709581 1.007709475 1.066499938 0.165439531 0.06656451 0.719895445 1.617773079 0.020092689 0.013826769 5.46E-09 8.262892497 0.058790463 LTQAEISEQPTMATVVPQVPTS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 LTQAEISEQPTMATVVPQVPTSPK 24 0 C9K0J5;Q70E73 C9K0J5 RAPH1 Ras-associated and pleckstrin homology domains-containing protein 1 1 0 LTQAEISEQPTMATVVPQVPT(0.281)S(0.719)PK 97.482 1.49E-05 6261900 2242.2 2175.3 2078.7 1673 1967 2436.2 2532.5 4625.2 2457.4 1869.6 TRUE FALSE FALSE 2064.727504 2363.323239 2155.738451 1666.077569 1943.54481 1930.904658 2603.555134 6035.402188 2187.829368 1934.568461 1.06728066 1.221628124 1.114325233 0.861214066 1.004639975 0.99810614 1.345806668 3.119766661 1.130913386 1 10.91779607 -4.253892694 2.99644967 1.036959289 3.48240314 0.97781282 0.092974588 0.038433138 0.493565874 0.012979526 0.225803393 5.57E-05 4.253892694 2.445443851 up LSPVIS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 LSPVISPR 8 0 Q08499-6;Q08499-7;Q08499-12 Q08499-6 PDE4D "cAMP-specific 3,5-cyclic phosphodiesterase 4D" 1 0 LSPVIS(1)PR 99.973 0.015068 35291000 3580.7 2837.3 3347.5 2923.4 3516.6 4815.3 4174.9 3134.5 3358.2 3382.4 TRUE FALSE FALSE 3297.283817 3082.543569 3471.561295 2911.303745 3474.666842 3816.5525 4292.036458 4090.194621 2989.813862 3499.938148 0.942097739 0.880742298 0.991892184 0.83181577 0.992779499 1.090462842 1.226317802 1.168647687 0.854247628 1 11.77311371 -5.092893155 2.550027268 0.956225195 1.196249642 0.754120073 0.061739174 0.101541651 1.275166519 0.007977227 0.025907006 8.07E-06 5.092893155 0.240024447 LSQSSQDS(ph)SPVRNLQSFGTEEPAYSTR ddPTM_HeLa_Curcumin_4h_R1 1 LSQSSQDSSPVRNLQSFGTEEPAYSTR 27 1 O95251-4;O95251;O95251-2 O95251-4 KAT7 Histone acetyltransferase KAT7 1 0 LS(0.001)QS(0.008)S(0.017)QDS(0.476)S(0.476)PVRNLQS(0.013)FGT(0.009)EEPAYSTR 48.204 0.010782 15918000 813.1 318.07 529.5 792.87 506.75 755.18 366.45 260.72 997.94 617.06 TRUE FALSE FALSE 748.742277 345.5625535 549.1237358 789.589314 500.7073372 598.5471554 376.7316008 340.2123278 888.4684787 638.5027891 1.172653103 0.541207587 0.860017756 1.236626257 0.784189742 0.93742293 0.590023422 0.532828256 1.391487232 1 9.318549112 -3.987983025 0.48552674 1.050024207 2.46E-14 0.382431417 0.224353707 4.048365432 0.531694738 0.043749363 2.566277149 0.000102806 3.987983025 -1.050024207 LSQSSQDSS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 5 LSQSSQDSSPVR 12 0 O95251-4;O95251;O95251-2 O95251-4 KAT7 Histone acetyltransferase KAT7 1 0 LSQSSQDS(0.004)S(0.996)PVR;LSQSSQDS(0.003)S(0.997)PVR;LSQSSQDS(0.031)S(0.969)PVR;LSQSS(0.001)QDS(0.492)S(0.507)PVR;LSQSSQDS(0.242)S(0.758)PVR ;;;; 168 0.00012137 1146853000 22606.3 18788.2 20736.7 21492.6 21317.1 22455.8 14134.7 7584.57 21216.6 18781.1 TRUE FALSE FALSE 20816.9875 20412.16829 21505.22034 21403.66932 21062.90751 17798.21395 14531.28164 9897.070478 18889.19206 19433.74183 1.071177526 1.050346787 1.106591851 1.101366351 1.083831806 0.915840815 0.747734624 0.50927251 0.97197916 1 14.24627609 -4.561488821 1.536902126 1.049339053 0.45450287 0.940323107 0.044314043 0.110578708 0.359020352 0.006856684 0.083372852 2.74E-05 4.561488821 -0.594836183 LSRLMSGSS(ph)RSLER ddPTM_HeLa_Curcumin_4h_R1 2 LSRLMSGSSRSLER 14 2 F8WEJ8;F8WCI0;B5MC67;Q7Z6J6-2;Q7Z6J6 F8WEJ8 FRMD5 FERM domain-containing protein 5 1 0 LSRLMSGSS(0.999)RS(0.001)LER;LSRLMS(0.043)GS(0.043)S(0.913)RS(0.002)LER ; 123.11 0.0035815 56275000 6200.5 5696.3 5456.5 5155.8 6362.2 7302 5421.8 5025.1 5692.5 5793.4 TRUE FALSE FALSE 5709.723882 6188.66279 5658.72269 5134.466666 6286.33492 5787.482889 5573.921116 6557.229857 5068.046992 5994.720219 0.952458776 1.032352231 0.943951091 0.856498131 1.048645256 0.965430025 0.929805047 1.093834177 0.845418436 1 12.54947671 -4.248522046 24.30644986 0.972019668 1.093834292 0.254576692 0.065317278 1265.39703 2381026.482 0.006857691 0.163879568 5.64E-05 4.248522046 0.121814624 DVMSDETNNEETES(ph)PSQEFVNITK ddPTM_HeLa_Curcumin_4h_R1 3 DVMSDETNNEETESPSQEFVNITK 24 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 DVMSDETNNEET(0.002)ES(0.919)PS(0.079)QEFVNITK;DVMSDETNNEETES(0.999)PS(0.001)QEFVNITK;DVMSDETNNEETES(0.999)PSQEFVNITK ;; 194.11 1.50E-14 77260200 12346.9 9381.3 10326.4 11476.4 11330.8 14714.9 12117.6 18173.9 12854 11179.5 TRUE FALSE FALSE 11369.62984 10192.17777 10709.10547 11428.9137 11195.68761 11662.86387 12457.58724 23715.03845 11443.94836 11567.98679 0.982852941 0.881067549 0.925753604 0.987977762 0.967816424 1.008201693 1.076901925 2.050057531 0.98927744 1 13.49785019 -4.253639514 3.621758364 0.979014044 2.180153813 0.98652019 0.037696257 0.025266914 0.589812618 0.005927467 0.082582705 5.58E-05 4.253639514 1.20113977 up LSS(ph)DSFAR ddPTM_HeLa_Curcumin_4h_R1 1 LSSDSFAR 8 0 A0A087WSV0;Q9HB09-3;Q9HB09 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 0 LS(0.223)S(0.744)DS(0.033)FAR 112.11 0.01068 2485100 1340.6 1347.9 892.16 999.39 1065.7 1482 1103.2 671.34 1453.3 1029.3 TRUE FALSE FALSE 1234.490095 1464.40647 925.2242344 995.254789 1052.992224 1174.616494 1134.152823 876.0284755 1293.876626 1065.068098 1.159071516 1.374941632 0.868699603 0.934451788 0.988661875 1.102855767 1.064864138 0.822509356 1.214829951 1 10.05672996 LSS(ph)EDEEEDEAEDDQSEASGKK ddPTM_HeLa_Curcumin_4h_R1 2 LSSEDEEEDEAEDDQSEASGKK 22 1 G3V4G1;Q8NEJ9-2;Q8NEJ9 G3V4G1 NGDN Neuroguidin 1 0 LS(0.17)S(0.83)EDEEEDEAEDDQSEASGKK;LS(0.171)S(0.829)EDEEEDEAEDDQSEASGKK ; 193.93 1.83E-13 161257000 10194 8747.5 9524.7 9097.9 8541 11100.4 7238.8 5197.6 9331 7941.4 TRUE FALSE FALSE 9387.134143 9503.594922 9877.693761 9060.2553 8439.154153 8798.051913 7441.901246 6782.324313 8307.412645 8217.363059 1.142353584 1.156526109 1.202051521 1.102574541 1.026990543 1.070666082 0.905631307 0.825365055 1.010958453 1 13.00445979 -4.6139703 1.772276409 1.086955288 0.804560558 0.680718966 0.062340392 0.2633207 1.303641293 0.010955065 0.098865511 2.43E-05 4.6139703 -0.282394731 S(ph)LGDEGLNR ddPTM_HeLa_Curcumin_4h_R1 2 SLGDEGLNR 9 0 Q01970-2;Q01970 Q01970-2 PLCB3 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3" 1 0 S(1)LGDEGLNR;S(1)LGDEGLNR ; 127.83 0.0042596 29163000 1591.4 1341.53 1709.28 1477.86 2014.69 2601 2906.8 13484.2 1386.41 1400.12 TRUE FALSE FALSE 1465.439011 1457.485875 1772.62742 1471.745007 1990.666138 2061.523281 2988.356985 17595.47051 1234.324292 1448.774066 1.011502791 1.006013229 1.223536135 1.015855434 1.374034906 1.422943252 2.062679789 12.14507557 0.851978456 1 10.50061691 -4.253566135 3.655140519 1.081688658 13.46412348 0.99710434 0.177280696 0.012238872 0.294509901 0.030067561 0.414971061 5.58E-05 4.253566135 12.38243482 up GVSMS(ph)LPSS(ph)PLLPR ddPTM_HeLa_Curcumin_4h_R1 1 GVSMSLPSSPLLPR 14 0 Q9C0D5-2;Q9C0D5 Q9C0D5-2 TANC1 Protein TANC1 2 0 GVS(0.017)MS(0.982)LPS(0.286)S(0.715)PLLPR 92.151 0.010532 34013000 3316.6 2794.8 3338.5 3127.8 2885.5 3229.3 2177.4 476.81 3134.9 3095.3 TRUE FALSE FALSE 3054.08761 3036.370059 3462.227747 3114.857992 2851.092297 2559.506778 2238.491984 622.187174 2791.009313 3202.861445 0.953549713 0.948017924 1.080979557 0.972523491 0.890170351 0.799131284 0.698903784 0.194259785 0.871411193 1 11.64514567 -4.346977567 1.208860163 0.978743315 6.52E-20 0.923808405 0.065776413 0.204175716 0.273749353 0.008250411 0.23948524 4.50E-05 4.346977567 -0.978743315 down LSS(ph)PISK ddPTM_HeLa_Curcumin_4h_R1 1 LSSPISK 7 0 A0A494C142;Q99728-3;Q99728-2;Q99728 A0A494C142 BARD1 BRCA1-associated RING domain protein 1 1 0 LS(0.083)S(0.916)PISK 104.01 0.017686 12305000 11400 9776.4 11175 10895 11127 12304 10502 3349.2 10957 8884.2 TRUE FALSE FALSE 10497.67797 10621.42845 11589.15533 10849.91938 10994.31779 9752.011705 10796.65786 4370.355662 9755.044513 9192.925289 1.141930087 1.155391578 1.260660232 1.180246661 1.19595422 1.06081703 1.17445291 0.47540424 1.061146937 1 13.1663083 -4.257786055 24.99548631 1.108172989 0.475403999 0.865419032 0.077504925 118.3002068 809356.7772 0.013292024 0.132145182 5.52E-05 4.257786055 -0.63276899 LSS(ph)PVLHR ddPTM_HeLa_Curcumin_4h_R1 3 LSSPVLHR 8 0 Q16643-3;Q16643;Q16643-2;D6R9W4;D6RCR4 Q16643-3 DBN1 Drebrin 1 0 LS(0.128)S(0.872)PVLHR;LS(0.019)S(0.981)PVLHR;LS(0.045)S(0.955)PVLHR ;; 138.06 0.0034488 1225944800 12412 10990.2 10406.5 10730.7 10690.7 12307.8 8888.3 9024.7 13076.7 10628.7 TRUE FALSE FALSE 11429.5771 11940.14392 10792.17404 10686.29921 10563.22038 9755.023543 9137.681776 11776.28949 11642.21873 10998.04653 1.03923702 1.085660429 0.981280995 0.9716543 0.960463329 0.886977839 0.830845891 1.070761926 1.05857151 1 13.42495968 -6.024979523 1.642686021 1.02332935 0.923599385 0.343634089 0.062811068 0.308861914 1.654707105 0.009411192 0.019148092 9.44E-07 6.024979523 -0.099729965 LSS(ph)SASREPYK ddPTM_HeLa_Curcumin_4h_R1 1 LSSSASREPYK 11 1 J3QR07;Q96MU7-2;Q96MU7 J3QR07 YTHDC1 YTH domain-containing protein 1 1 0 LSS(0.942)S(0.055)AS(0.002)REPYK 131.12 0.00098451 0 1932.9 1832.8 1928.3 1921.1 1948.5 2627.8 1924.7 1145.1 2568.3 2220.3 TRUE FALSE FALSE 1779.908925 1991.219065 1999.764494 1913.150997 1925.26541 2082.764659 1978.701902 1494.235719 2286.563916 2297.45526 0.774730615 0.866706351 0.87042587 0.832726117 0.837999087 0.90655287 0.861258078 0.650387298 0.995259388 1 11.16582105 -9.415155403 1.045635082 1.003894169 0.827679428 0.511366916 0.06728517 0.379051065 0.714607867 0.051065327 0.011810467 3.84E-10 9.415155403 -0.176214741 LSS(ph)SDRYSDAS(ph)DDSFSEPR ddPTM_HeLa_Curcumin_4h_R1 1 LSSSDRYSDASDDSFSEPR 19 1 Q9NRF8 Q9NRF8 CTPS2 CTP synthase 2 2 0 LS(0.101)S(0.42)S(0.353)DRY(0.106)S(0.025)DAS(0.983)DDS(0.009)FS(0.003)EPR 71.143 0.0069709 9754300 2287 1697.4 1870.4 1988.5 1954.5 2098.3 1765.9 2014.9 2135.2 2056.1 TRUE FALSE FALSE 2105.981537 1844.115693 1939.718669 1980.272114 1931.193864 1663.088927 1815.446401 2629.233735 1900.973902 2127.549322 0.989862616 0.866779291 0.911715018 0.930776125 0.907708152 0.781692302 0.853304026 1.235803893 0.893504034 1 11.05497686 -7.369981504 7.759388788 0.995496523 0.917322117 0 0.117140077 0.500928942 32.2360405 0.018360533 0.020947816 4.27E-08 7.369981504 -0.078174406 LSS(ph)SLER ddPTM_HeLa_Curcumin_4h_R1 1 LSSSLER 7 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 0 LS(0.001)S(0.5)S(0.5)LER 109.48 0.016161 11797000 4890.1 4091.7 3995.2 4506.5 4686.1 6387.9 5257.1 2099.2 5216.7 3812.1 TRUE FALSE FALSE 4503.043425 4445.368316 4143.265627 4487.853297 4630.221318 5062.977534 5404.600077 2739.236416 4644.441062 3944.570191 1.14158025 1.126958857 1.050371885 1.137729354 1.173821505 1.283530851 1.370136622 0.694432165 1.177426395 1 11.94565239 -9.402850396 0.521354022 0.964944031 1.141457628 0 0.176731234 3.333704705 1.146550591 0.304223276 0.040088349 3.96E-10 9.402850396 0.176513597 LSS(ph)SSATLLNSPDR ddPTM_HeLa_Curcumin_4h_R1 1 LSSSSATLLNSPDR 14 0 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;A0A087WZ40 Q14244-3 MAP7 Ensconsin 1 0 LSS(0.566)S(0.284)S(0.146)AT(0.004)LLNSPDR 272.77 7.87E-51 28615000 1183.3 1118.8 1444.3 1212.9 1319.6 1259.6 1332.3 2724.3 1528.5 1565.9 TRUE FALSE FALSE 1089.640556 1215.504087 1497.827029 1207.881341 1303.864632 998.3447614 1369.680752 3554.926529 1360.827374 1620.314908 0.672486904 0.750165342 0.924404892 0.745460858 0.804698287 0.616142428 0.845317626 2.19397261 0.83985364 1 10.66205851 -4.261946438 6.693138041 0.815887552 2.218254011 0.937688696 0.107769654 0.02510242 7.407378701 0.019412076 0.159156884 5.47E-05 4.261946438 1.402366459 LSS(ph)TDDGYIDLQFK ddPTM_HeLa_Curcumin_4h_R1 1 LSSTDDGYIDLQFK 14 0 Q5JWB9;A0A087WTT2;Q96A57;Q96A57-2 Q5JWB9 TMEM230 Transmembrane protein 230 1 0 LS(0.041)S(0.779)T(0.177)DDGY(0.003)IDLQFK 84.734 0.01478 8961500 1274.7 1124.2 1179.6 1697.8 1328.5 1818.7 1673.9 1795.4 1609.9 1387.8 TRUE FALSE FALSE 1173.80615 1221.370839 1223.317014 1690.774953 1312.658505 1441.481119 1720.865129 2342.809195 1433.297998 1436.025947 0.817398984 0.850521428 0.851876678 1.17739861 0.914091078 1.003798798 1.198352393 1.631453248 0.998100348 1 10.4878661 -1.000001055 0.737418335 0.913130189 120.0453126 0.81975901 0.09819354 101.9936427 0.435118949 0.017284397 20172.33121 0.099999757 1.000001055 119.1321824 LSS(ph)TPPLSALGR ddPTM_HeLa_Curcumin_4h_R1 1 LSSTPPLSALGR 12 0 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 1 0 LSS(0.603)T(0.392)PPLS(0.004)ALGR 112.84 0.0047338 26699000 2954 2599.7 2699 2726.6 2831.5 3414.1 2935.8 1001.9 2824 3181.3 TRUE FALSE FALSE 2720.187783 2824.406484 2799.027314 2715.318052 2797.736212 2705.977175 3018.170647 1307.374698 2514.214265 3291.849938 0.826340153 0.857999768 0.85029007 0.824860824 0.849897858 0.822023247 0.916861553 0.397155011 0.763769404 1 11.68468286 -4.259595098 24.93799228 0.890749912 0.397154838 0.795203685 0.068068539 54.44376043 736114.9633 0.010844941 0.093817801 5.50E-05 4.259595098 -0.493595073 LSSGDPSTSPSLSQT(ph)TPSKDTDDQSRK ddPTM_HeLa_Curcumin_4h_R1 1 LSSGDPSTSPSLSQTTPSKDTDDQSRK 27 2 Q99504-2;Q99504-4;Q99504-5;Q99504-3;Q99504 Q99504-2 EYA3 Eyes absent homolog 3 1 0 LSSGDPS(0.006)T(0.006)S(0.006)PS(0.104)LS(0.09)QT(0.392)T(0.392)PS(0.005)KDTDDQSRK 74.222 0.00013121 0 1185.3 886.36 1225.7 1188.3 905.59 874.53 893.6 525.09 1303.2 1393.1 TRUE FALSE FALSE 1091.482254 962.9730089 1271.12552 1183.383129 894.7914307 693.14262 918.672011 685.1875238 1160.24222 1441.510121 0.757179737 0.668030695 0.881801315 0.820932931 0.620731979 0.480844782 0.637298342 0.475326197 0.804879691 1 10.49336525 -5.202675568 0.105929096 1.243310449 4.56E-13 0.583074768 0.10402112 13.07006568 0.327453504 1.099462913 2.993699166 6.27E-06 5.202675568 -1.243310449 LSSGDPSTSPSLSQTT(ph)PSKDTDDQSR ddPTM_HeLa_Curcumin_4h_R1 1 LSSGDPSTSPSLSQTTPSKDTDDQSR 26 1 Q99504-2;Q99504-4;Q99504-5;Q99504-3;Q99504 Q99504-2 EYA3 Eyes absent homolog 3 1 0 LSSGDPSTSPSLSQT(0.089)T(0.754)PS(0.064)KDT(0.089)DDQS(0.003)R 79.069 9.48E-05 5866500 2235.2 1634.2 1865 2599 2030.2 2788.9 2247.9 1376.1 2347.4 2092.4 TRUE FALSE FALSE 2058.281561 1775.452966 1934.118541 2588.246027 2005.991191 2210.450703 2310.970024 1795.666555 2089.896093 2165.110744 0.95065879 0.820028708 0.893311599 1.195433552 0.92650743 1.020941173 1.067368046 0.829364761 0.965260599 1 11.0802251 AEDGAT(ph)PS(ph)PSNETPK ddPTM_HeLa_Curcumin_4h_R1 4 AEDGATPSPSNETPK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 2 0 AEDGAT(1)PS(0.996)PS(0.004)NETPK;AEDGAT(1)PS(0.876)PS(0.027)NET(0.098)PK;AEDGAT(1)PS(0.987)PS(0.013)NETPK;AEDGAT(1)PS(0.5)PS(0.5)NETPK ;;; 203.52 3.07E-10 96424000 20918.1 17953.9 17634.6 17752.3 19089.7 23675 14386.9 6606.9 20116.5 17825.5 TRUE FALSE FALSE 19262.41031 19505.75511 18288.15379 17678.84569 18862.0678 18764.53813 14790.55769 8621.313396 17909.77028 18444.9348 1.044319783 1.057512826 0.991500051 0.958466152 1.022615043 1.017327431 0.801876388 0.46740818 0.970985828 1 14.17093707 -4.346368998 1.9241364 1.018490475 0.35344436 0.96398797 0.0321493 0.077774338 0.342536846 0.00453102 0.086041741 4.50E-05 4.346368998 -0.665046115 down LSSGPEQITLEASSTEGHPGAPS(ph)PQHTDQTEAFQK ddPTM_HeLa_Curcumin_4h_R1 1 LSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQK 35 0 H3BND4;Q6P996-3;Q6P996-4;Q6P996-5;Q6P996 H3BND4 PDXDC1 Pyridoxal-dependent decarboxylase domain-containing protein 1 1 0 LSSGPEQIT(0.001)LEAS(0.05)S(0.05)T(0.059)EGHPGAPS(0.615)PQHT(0.206)DQT(0.018)EAFQK 58.612 0.0002267 4777000 1464.6 1203.2 1137.6 1459.7 1464.7 475.05 410.72 715.88 1750.2 1239.8 TRUE FALSE FALSE 1348.675365 1307.199247 1179.760457 1453.660148 1447.234409 376.5192751 422.2436978 934.1485165 1558.207439 1282.882958 1.051284809 1.01895441 0.919616595 1.133119853 1.128111026 0.293494643 0.329136571 0.728163478 1.214613874 1 10.32517384 -5.264213305 24.99945235 1.030658141 0.438152051 0.810230436 0.13586192 64.30644816 579551.9901 0.016507146 0.038524956 5.44E-06 5.264213305 -0.59250609 LSSLIILMPHHVEPLER ddPTM_HeLa_Curcumin_4h_R1 1 LSSLIILMPHHVEPLER 17 0 P50454;E9PR70;E9PPV6;E9PKH2 P50454 SERPINH1 Serpin H1 0 0 46.701 0.014585 1577800 705.25 631.06 679.64 467.39 540.57 1515.6 707.08 400.8 686.44 768.93 FALSE FALSE TRUE 649.4287183 685.6060145 704.8280563 465.456064 534.1240558 1201.247476 726.9187618 523.0020749 611.1392494 795.6502603 0.81622385 0.861692692 0.8858516 0.585000832 0.671305073 1.509768218 0.913615942 0.657326593 0.768100358 1 9.635990602 -9.441714735 1.173394298 0.999992807 0.86589331 0 0.251151561 1.556910726 3.834140152 0.168524883 0.042058144 3.62E-10 9.441714735 -0.134099497 LSSLPFQK ddPTM_HeLa_Curcumin_4h_R1 2 LSSLPFQK 8 0 H3BRV9;P61970 H3BRV9 NUTF2 Nuclear transport factor 2 0 0 ; ; 116.9 0.003061 72642000 4734.3 3570.1 4540 4106.1 4318.3 7171.9 4685.5 4905 4653.4 3798.3 FALSE FALSE TRUE 4359.575159 3878.683536 4708.256394 4089.110046 4266.807093 5684.367096 4816.96252 6400.51192 4142.933662 3930.290642 1.109224624 0.986869392 1.197941023 1.040409074 1.085621263 1.446296881 1.22559957 1.628508551 1.054103637 1 11.94042029 -1 0.40968578 1.039886357 10.65664932 0.748593192 0.099445399 22.36222829 0.260118728 0.022057931 176.7442429 0.1 1 9.616762963 LSSLRAS(ph)TSKSESSQK ddPTM_HeLa_Curcumin_4h_R1 1 LSSLRASTSKSESSQK 16 2 P62753;A2A3R5 P62753 RPS6 40S ribosomal protein S6 1 0 LS(0.051)S(0.044)LRAS(0.863)T(0.041)S(0.001)KSESSQK 82.663 0.0077957 38426000 1592.5 1289 754.4 1469 1185.3 3056.5 2858.2 2312.7 3081.3 2052.6 TRUE FALSE FALSE 1466.451945 1400.415416 782.3587276 1462.921667 1171.166072 2422.547446 2938.3934 3017.831584 2743.289099 2123.927697 0.69044344 0.659351737 0.36835469 0.688781294 0.551415226 1.140597888 1.383471482 1.42087303 1.29161134 1 11.05251894 -5.022349149 3.813930728 0.768649344 1.388930232 0.556782461 0.23754149 0.115417711 3.659264238 0.031097292 0.093328349 9.50E-06 5.022349149 0.620280888 LSSPAAFLPACNS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 LSSPAAFLPACNSPSK 16 0 Q86YS7;H0YFE9;Q86YS7-5;Q86YS7-3;Q86YS7-2;Q86YS7-4 Q86YS7;Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 0 LSSPAAFLPACNS(0.967)PS(0.033)K 119.51 0.00096953 71028000 3392.5 3022.6 3165.3 3075.2 3577.6 3162.6 2848.7 2460.8 3126.5 2868.4 TRUE FALSE FALSE 3123.980045 3283.860076 3282.608802 3062.475637 3534.939457 2506.64111 2928.626855 3211.086592 2783.530772 2968.076686 1.052526729 1.106393272 1.105971695 1.031804755 1.190986565 0.844533809 0.986708621 1.081874537 0.937823064 1 11.53531265 -3.826246329 9.256597749 1.033751176 3.035080473 0.026849796 0.091613089 159024.0368 132410.592 0.011760926 6516828.094 0.000149195 3.826246329 2.001329297 LSSPAAFLPACNSPS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 LSSPAAFLPACNSPSK 16 0 Q86YS7;H0YFE9;Q86YS7-5;Q86YS7-3;Q86YS7-2;Q86YS7-4 Q86YS7;Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 0 LSSPAAFLPACNS(0.321)PS(0.679)K 152.59 0.00033434 55284000 3423.7 2957.9 3303.3 3204.9 3089.2 3224.6 2579.3 2430.2 3007.9 2710.3 TRUE FALSE FALSE 3152.710532 3213.567696 3425.723204 3191.638973 3052.363308 2555.781611 2651.668216 3171.156793 2677.940895 2804.482723 1.124168285 1.145868245 1.221516958 1.138049076 1.088387275 0.911320148 0.945510626 1.130745705 0.954878728 1 11.45351898 -5.30399433 23.12688068 1.086960185 0.990823997 0.206584334 0.088618325 246.7550096 134100.8553 0.013196234 0.029508124 4.97E-06 5.30399433 -0.096136188 LSSPVLHR ddPTM_HeLa_Curcumin_4h_R1 1 LSSPVLHR 8 0 Q16643-3;Q16643;Q16643-2;D6R9W4;D6RCR4 Q16643-3 DBN1 Drebrin 0 0 118.74 0.0069184 5110400 7658.4 5730.7 5857.3 6118 6433.2 6661.4 5043.7 3702.6 6921.3 6041.8 FALSE FALSE TRUE 7052.229559 6226.036172 6074.376691 6092.685337 6356.488292 5279.750551 5185.212648 4831.505695 6162.050706 6251.7521 1.128040499 0.995886605 0.971627888 0.974556451 1.016753094 0.844523338 0.829401512 0.772824261 0.985651799 1 12.61004486 -5.01712899 0.67456805 1.05502017 0.714762783 0.744779837 0.05055095 0.548974762 0.298718502 0.010867691 0.117895517 9.61E-06 5.01712899 -0.340257387 LSSS(ph)PGLFGAFSVR ddPTM_HeLa_Curcumin_4h_R1 2 LSSSPGLFGAFSVR 14 0 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 LS(0.011)S(0.141)S(0.848)PGLFGAFSVR;LS(0.026)S(0.175)S(0.789)PGLFGAFS(0.011)VR ; 188.09 1.37E-05 74366000 3015.2 2293.97 2798.2 2942.8 3070.9 3625.2 5100.5 1333.11 3081.3 2672.3 TRUE FALSE FALSE 2776.543738 2492.250545 2901.903754 2930.623473 3034.281523 2873.292656 5243.606303 1739.569102 2743.289099 2765.162226 1.004116038 0.901303555 1.049451539 1.059837808 1.097324958 1.039104552 1.89631055 0.629102006 0.992089749 1 11.43314841 -4.960953083 24.99999638 1.010089531 1.313956545 0.098567697 0.288460061 185.5606185 118804.2977 0.033994937 0.101984552 1.09E-05 4.960953083 0.303867014 LSSS(ph)S(ph)PGATVSPSSSDAEYDKLPDADLAR ddPTM_HeLa_Curcumin_4h_R1 1 LSSSSPGATVSPSSSDAEYDKLPDADLAR 29 1 Q8NI08-2;Q8NI08;Q8NI08-7;Q8NI08-4;Q8NI08-3 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 2 0 LS(0.219)S(0.205)S(0.41)S(0.41)PGAT(0.402)VS(0.265)PS(0.067)S(0.005)S(0.014)DAEY(0.002)DKLPDADLAR 56.172 0.0025383 15279000 1325.4 1158.6 1143.7 1061.4 1380.1 1640.2 1036.5 1111.9 1547.7 1585.6 TRUE FALSE FALSE 1220.493191 1258.744221 1186.086528 1057.008208 1363.643209 1300.004031 1065.5814 1450.913191 1377.921182 1640.699482 0.743885888 0.767199743 0.72291516 0.644242422 0.831135271 0.792347438 0.64946775 0.884325989 0.839837641 1 10.6800953 -9.14803381 0.720072552 1.015582937 0.748183427 0.312514335 0.085067226 0.376739768 0.32348559 0.059735558 0.013932563 7.11E-10 9.14803381 -0.26739951 LSSS(ph)SATLLNS(ph)PDR ddPTM_HeLa_Curcumin_4h_R1 2 LSSSSATLLNSPDR 14 0 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;A0A087WZ40 Q14244-3 MAP7 Ensconsin 2 0 LS(0.054)S(0.089)S(0.682)S(0.112)AT(0.062)LLNS(1)PDR;LS(0.006)S(0.123)S(0.865)S(0.005)AT(0.001)LLNS(1)PDR ; 148.33 0.0013255 23406800 5844.1 5007.3 5752.6 5639.9 5837.7 8242.9 6549.9 3941.3 6118.4 5787.8 TRUE FALSE FALSE 5381.533318 5440.1087 5965.796417 5616.563588 5768.08924 6533.229623 6733.672566 5142.984226 5447.226827 5988.925619 0.898580757 0.908361373 0.996138005 0.937824903 0.963125877 1.090885083 1.124354015 0.858749057 0.909549922 1 12.5480815 -5.418929451 7.276534383 0.950138824 1.03433038 0.198040321 0.07276336 0.31389146 19.3895588 0.010349437 0.023225445 3.81E-06 5.418929451 0.084191556 LSSS(ph)SATLLNSPDR ddPTM_HeLa_Curcumin_4h_R1 1 LSSSSATLLNSPDR 14 0 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;A0A087WZ40 Q14244-3 MAP7 Ensconsin 1 0 LSS(0.003)S(0.988)S(0.009)ATLLNSPDR 201.3 6.47E-09 18056000 1211.9 1061.3 1028.2 821.06 1341.3 1210.9 1074.4 2236.1 1652.5 1519.4 TRUE FALSE FALSE 1115.976836 1153.034043 1066.305996 817.6626713 1325.305874 959.7456903 1104.544772 2917.876596 1471.224884 1572.199037 0.709819056 0.733389358 0.67822583 0.5200758 0.842963163 0.610447957 0.702547671 1.85592061 0.93577521 1 10.61856816 -1.297211261 11.04383786 0.838986 1.026775097 0 0.359957335 0 0 0.044341809 0 0.050441587 1.297211261 0.187789098 LSSSDRYS(ph)DAS(ph)DDSFSEPR ddPTM_HeLa_Curcumin_4h_R1 1 LSSSDRYSDASDDSFSEPR 19 1 Q9NRF8 Q9NRF8 CTPS2 CTP synthase 2 2 0 LSSS(0.008)DRY(0.001)S(0.99)DAS(0.948)DDS(0.052)FSEPR 161.31 8.11E-16 0 1362.9 1043.1 1034.9 1110.4 773.28 1388.8 1154.1 1242.1 1262.6 1102.2 TRUE FALSE FALSE 1255.025027 1133.260916 1073.254304 1105.805459 764.059141 1100.747225 1186.48094 1620.810572 1124.095939 1140.501368 1.100415188 0.993651518 0.941037279 0.969578371 0.669932683 0.965143275 1.040315227 1.421138648 0.985615599 1 10.15545246 -4.26435651 4.060327649 1.000006302 1.456518073 0.5878196 0.11177682 0.147217112 5.156932172 0.017516044 0.195561684 5.44E-05 4.26435651 0.456511771 LSSSDRYS(ph)DASDDSFSEPR ddPTM_HeLa_Curcumin_4h_R1 1 LSSSDRYSDASDDSFSEPR 19 1 Q9NRF8 Q9NRF8 CTPS2 CTP synthase 2 1 0 LS(0.006)S(0.006)S(0.003)DRYS(0.491)DAS(0.491)DDS(0.003)FSEPR 132.87 0.00164 5171600 1070.1 1198.7 1137.6 1099.5 1324.4 1509.5 941.03 890.79 1283.9 1341.3 TRUE FALSE FALSE 985.4004558 1302.310287 1179.760457 1094.95056 1308.607395 1196.412684 967.4327691 1162.38777 1143.059382 1387.910075 0.70998869 0.938324687 0.850026582 0.788920392 0.942861802 0.862024641 0.697042832 0.837509426 0.823583172 1 10.43869838 -9.581690451 1.365436244 1.000048226 0.815613622 0 0.094412229 0.350383065 1.170913888 0.059168181 0.01378251 2.62E-10 9.581690451 -0.184434604 LSSSES(ph)PQRDPPPPPPPPPLLR ddPTM_HeLa_Curcumin_4h_R1 1 LSSSESPQRDPPPPPPPPPLLR 22 1 J3KS33;Q9H2G4 J3KS33 TSPYL2 Testis-specific Y-encoded-like protein 2 1 0 LS(0.198)S(0.17)S(0.17)ES(0.463)PQRDPPPPPPPPPLLR 51.232 0.011314 6093400 452.38 575.46 609.52 385.19 559.92 487.35 448.94 402.98 724.31 502.98 TRUE FALSE FALSE 416.5736457 625.2001982 632.1093474 383.5961858 553.2433197 386.2681164 461.5360481 525.8467469 644.8550051 520.4585176 0.800397403 1.201248855 1.214523975 0.737035081 1.062992152 0.742168883 0.886787386 1.010352851 1.239013261 1 9.02363937 -4.234260267 20.67805902 0.931656531 1.010353874 0 0.19029118 3229.372181 2456504.183 0.022994471 1.670197132 5.83E-05 4.234260267 0.078697342 LSSSGAPPADFPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 LSSSGAPPADFPSPR 15 0 Q8NG08 Q8NG08 HELB DNA helicase B 1 0 LSSSGAPPADFPS(1)PR;LSSSGAPPADFPS(1)PR ; 233.47 3.77E-21 9341000 4235 3792.4 3929.9 3824.9 3716.5 4741.2 3444.8 3630.8 4524.3 3769.9 TRUE FALSE FALSE 3899.795281 4120.198157 4075.545551 3809.073577 3672.183165 3757.821676 3541.451817 4737.814206 4027.995609 3900.903744 0.999715845 1.05621631 1.044769576 0.976459258 0.941367284 0.96332079 0.907854192 1.21454271 1.032580108 1 11.92959268 -6.15396323 15.45868054 1.008170002 0.990181174 0 0.080493793 9.011675764 1271.451657 0.011247332 0.018652357 7.02E-07 6.15396323 -0.017988828 SPQGPSPVLAEDS(ph)EGEG ddPTM_HeLa_Curcumin_4h_R1 1 SPQGPSPVLAEDSEGEG 17 0 Q99638 Q99638 RAD9A Cell cycle checkpoint control protein RAD9A 1 0 SPQGPSPVLAEDS(1)EGEG 127.88 0.00033933 10799000 4598.5 3944.3 4414.5 4470.1 4296.7 5732.4 4596.9 7878.7 4962.5 3932.5 TRUE FALSE FALSE 4234.523873 4285.227717 4578.105253 4451.603911 4245.464659 4543.435623 4725.876642 10280.87936 4418.126166 4069.154082 1.040639845 1.053100382 1.125075424 1.093987551 1.043328557 1.116555316 1.161390438 2.526539707 1.085760351 1 11.9905132 -4.253458099 3.776038547 1.043626799 2.691553184 0.990216948 0.043153434 0.021222685 0.569704029 0.007340664 0.097923992 5.58E-05 4.253458099 1.647926385 up LSSSSATLLNS(ph)PDR ddPTM_HeLa_Curcumin_4h_R1 4 LSSSSATLLNSPDR 14 0 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;A0A087WZ40 Q14244-3 MAP7 Ensconsin 1 0 LSSSSATLLNS(1)PDR;LSSSSATLLNS(1)PDR;LSSSSATLLNS(1)PDR;LSSSSATLLNS(1)PDR ;;; 244.23 8.11E-29 633609000 9943.7 7185.45 9560.1 8521.7 9455.1 11513.9 8632.2 2281.96 9148.17 7575.7 TRUE FALSE FALSE 9156.645652 7806.52828 9914.405716 8486.439463 9342.354108 9125.787352 8874.3963 2977.719099 8144.638639 7838.955011 1.168095191 0.995863386 1.264761145 1.082598312 1.191785652 1.164158659 1.132089199 0.379861741 1.038995456 1 12.93644563 -4.260072437 24.98517781 1.103644167 0.379861504 0.875068187 0.083266959 31.77965566 580810.4176 0.012519738 0.10495628 5.49E-05 4.260072437 -0.723782662 S(ph)PSASSVGSR ddPTM_HeLa_Curcumin_4h_R1 1 SPSASSVGSR 10 0 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 0 S(0.694)PS(0.291)AS(0.014)S(0.001)VGSR 103.31 0.010486 29357000 1375.7 1262.1 1442 1226.5 1249.8 1212.2 1029.2 251.16 1491.3 1568.4 TRUE FALSE FALSE 1266.811893 1371.1903 1495.441789 1221.425068 1234.896951 960.7760557 1058.076582 327.7375278 1327.708121 1622.901783 0.780584448 0.84490036 0.921461671 0.752617984 0.760919092 0.592011214 0.651965876 0.201945386 0.8181075 1 10.66435998 -4.345314021 0.553327494 0.900516545 8.02E-32 0.809048295 0.091501273 1.200616569 0.261445978 0.019716244 0.680308662 4.52E-05 4.345314021 -0.900516545 down LSSSSPGATVS(ph)PSSS(ph)DAEYDKLPDADLAR ddPTM_HeLa_Curcumin_4h_R1 1 LSSSSPGATVSPSSSDAEYDKLPDADLAR 29 1 Q8NI08-2;Q8NI08;Q8NI08-7;Q8NI08-4;Q8NI08-3 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 2 0 LS(0.001)S(0.001)S(0.004)S(0.006)PGAT(0.072)VS(0.482)PS(0.366)S(0.366)S(0.51)DAEY(0.193)DKLPDADLAR 55.394 0.0027187 28322000 1639.6 1308.5 1698.9 1562.9 1476.7 2140.5 1553.7 803.36 1993.2 1363 TRUE FALSE FALSE 1509.82393 1421.600909 1761.862729 1556.433134 1459.091317 1696.536172 1597.29264 1048.300766 1774.550947 1410.364149 1.070520639 1.007967276 1.249225408 1.103568277 1.034549353 1.202906479 1.132539169 0.743283759 1.258221821 1 10.46185199 -3.239307679 12.99526038 1.0534716 1.074480489 0 0.145989527 0 0 0.016241266 0 0.000576358 3.239307679 0.02100889 LSSSSPGATVSPS(ph)S(ph)S(ph)DAEYDKLPDADLAR ddPTM_HeLa_Curcumin_4h_R1 1 LSSSSPGATVSPSSSDAEYDKLPDADLAR 29 1 Q8NI08-2;Q8NI08;Q8NI08-7;Q8NI08-4;Q8NI08-3 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 3 0 LS(0.001)S(0.001)S(0.003)S(0.007)PGAT(0.052)VS(0.33)PS(0.749)S(0.853)S(0.853)DAEY(0.151)DKLPDADLAR 69.528 0.00051865 0 783.48 627.5 495.89 647.35 532.13 712.44 500.21 366.06 715.82 751.57 TRUE FALSE FALSE 721.4667313 681.7383039 514.2681196 644.6714372 525.7846973 564.6719131 514.2445464 477.6700089 637.2963369 777.6870016 0.927708358 0.876622989 0.661279047 0.828960026 0.676087804 0.726091489 0.661248735 0.614218841 0.819476648 1 9.603045815 -6.778545958 0.541044237 0.994316178 0.644561259 0.599300547 0.078269658 0.212536721 0.133446401 0.016290568 0.028904685 1.67E-07 6.778545958 -0.349754919 LSSSSPGATVSPSSS(ph)DAEYDKLPDADLAR ddPTM_HeLa_Curcumin_4h_R1 1 LSSSSPGATVSPSSSDAEYDKLPDADLAR 29 1 Q8NI08-2;Q8NI08;Q8NI08-7;Q8NI08-4;Q8NI08-3 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 0 LSSSSPGAT(0.008)VS(0.223)PS(0.223)S(0.223)S(0.322)DAEYDKLPDADLAR 110.03 8.22E-11 101270000 1431.2 1248.1 1341.2 1069.9 1374.9 1368.3 1209 955.59 1495.3 1231 TRUE FALSE FALSE 1317.91901 1355.980203 1390.906052 1065.473037 1358.505215 1084.499156 1242.921286 1246.944992 1331.269331 1273.777158 1.034654297 1.064534871 1.091953991 0.836467376 1.066517174 0.851404148 0.975776083 0.97893496 1.045135189 1 10.31489719 -6.282385164 24.99745995 1.026313151 0.945610905 0.365512182 0.066567137 783.0686653 934540.8643 0.009461706 0.01446297 5.22E-07 6.282385164 -0.080702247 LSSSTVAISYS(ph)PDR ddPTM_HeLa_Curcumin_4h_R1 3 LSSSTVAISYSPDR 14 0 Q96T17;Q96T17-2;Q96T17-5 Q96T17 MAP7D2 MAP7 domain-containing protein 2 1 0 LSSSTVAISYS(1)PDR;LSSSTVAISYS(1)PDR;LSSSTVAISYS(1)PDR ;; 259.27 4.72E-39 117374000 4231.5 3113.02 4116.11 3410.36 4285.5 4649.44 3617.1 2126.65 3335.23 3272.58 TRUE FALSE FALSE 3896.57231 3382.095577 4268.656657 3396.248834 4234.398211 3685.093734 3718.586091 2775.055795 2969.363613 3386.301911 1.150686623 0.998757838 1.260565883 1.0029374 1.25044911 1.088235435 1.098125976 0.819494501 0.876875037 1 11.72549489 -4.260397021 24.47468427 1.090175333 0.819494388 0.321313683 0.113157165 48.19093426 1131308.724 0.012650649 0.103670877 5.49E-05 4.260397021 -0.270680945 LSSTWEGIQAGK ddPTM_HeLa_Curcumin_4h_R1 1 LSSTWEGIQAGK 12 0 F2Z393;P37837 F2Z393 TALDO1 Transaldolase 0 0 157.38 5.69E-24 0 250.93 165.67 223.41 135.24 285.48 308.22 152.28 128.97 272.21 176.43 FALSE FALSE TRUE 231.0686257 179.9897766 231.6897711 134.6804127 282.0758375 244.2916976 156.552567 168.2923593 242.349244 182.5609294 1.265706888 0.985916194 1.269109288 0.737728566 1.545105179 1.338137895 0.857535988 0.921842148 1.327497865 1 7.512234231 -4.734474495 24.99179699 1.141938851 0.889688758 0.206807674 0.218381216 281.8752459 261245.4733 0.028807267 0.107730607 1.84E-05 4.734474495 -0.252250093 LSSWDQAET(ph)PGHTPSLR ddPTM_HeLa_Curcumin_4h_R1 2 LSSWDQAETPGHTPSLR 17 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 LSSWDQAET(1)PGHTPSLR;LSSWDQAET(0.998)PGHTPS(0.001)LR ; 125.75 0.00038378 23464800 2694 2625.35 3123.5 2791.8 3314.38 5201.5 3735.4 1633.55 2839.83 2523.87 TRUE FALSE FALSE 2480.767057 2852.273556 3239.259658 2780.248271 3274.858183 4122.650267 3840.205271 2131.611875 2528.307754 2611.574295 0.949912496 1.092166346 1.240347504 1.064587087 1.253978564 1.578607308 1.470456069 0.816217206 0.968116342 1 11.35070403 -6.594089487 1.044546671 0.974846796 1.294462219 0.260944787 0.196528878 0.421440892 0.919360573 0.036052858 0.061382728 2.55E-07 6.594089487 0.319615423 SPS(ph)PAHLPDDPK ddPTM_HeLa_Curcumin_4h_R1 2 SPSPAHLPDDPK 12 0 A0A087X183;H0Y4V9;Q92615;H0Y641 A0A087X183 LARP4B La-related protein 4B 1 0 S(0.159)PS(0.841)PAHLPDDPK;S(0.161)PS(0.839)PAHLPDDPK ; 112.17 0.0023311 592770000 36278 31921 31734 29737 39327 37042 22774 7106.1 34524 27477 TRUE FALSE FALSE 33406.55802 34680.109 32910.08996 29613.95617 38858.05121 29359.07165 23412.97715 9272.717178 30736.80357 28431.8237 1.174970637 1.219763789 1.157508934 1.041577793 1.366709769 1.032613031 0.823477853 0.32613867 1.081070419 1 14.79521902 -4.344614861 1.905077264 1.115432349 0.164341463 0.85832032 0.101545284 0.200502575 0.857873048 0.016316591 0.315611238 4.52E-05 4.344614861 -0.951090886 down LSTMETGTGLIR ddPTM_HeLa_Curcumin_4h_R1 1 LSTMETGTGLIR 12 0 A0A494C1B8;A0A494C0U1;Q5VZU9;P29144 A0A494C1B8 TPP2 Tripeptidyl-peptidase 2 0 0 101.46 0.012493 16382000 1248.7 2527.8 1242.7 1199.2 2249.6 2991.5 2560.1 1143.3 1066 498.71 FALSE FALSE TRUE 1149.864077 2746.291768 1288.755555 1194.238028 2222.774989 2371.029179 2631.929516 1491.886907 949.062467 516.0401354 2.228245438 5.321856926 2.497394034 2.314234778 4.307368433 4.594660408 5.100241891 2.891028826 1.839125297 1 9.011339466 -7.693616187 0.442996653 0.879221841 4.234623368 0.426137757 1.079154863 0.515186343 0.263058648 0.63611424 0.501186357 2.02E-08 7.693616187 3.355401526 AILDAEPGPRPALQPS(ph)PSIRLPLDAPLPGSK ddPTM_HeLa_Curcumin_4h_R1 1 AILDAEPGPRPALQPSPSIRLPLDAPLPGSK 31 2 B5MD46;Q9BXI6;Q9BXI6-2 B5MD46 TBC1D10A TBC1 domain family member 10A 1 0 AILDAEPGPRPALQPS(0.782)PS(0.199)IRLPLDAPLPGS(0.02)K 63.291 0.00021093 22180000 1218.1 1034 1065.9 888.57 982.33 1253.9 811.3 401.11 1762.9 1360.1 TRUE FALSE FALSE 1121.6861 1123.374353 1105.403192 884.8933328 970.6163563 993.8270056 834.0628945 523.4065925 1569.514281 1407.363374 0.797012428 0.798212014 0.785442631 0.628759672 0.689670041 0.706162335 0.592642178 0.371905794 1.115216091 1 10.45877916 -4.344015177 0.152839946 1.086831958 2.10E-16 0.848725644 0.076772911 5.951581464 0.161441617 0.196790651 1.334042725 4.53E-05 4.344015177 -1.086831958 down LSTTPS(ph)PT(ph)SSLHEDGVEDFRR ddPTM_HeLa_Curcumin_4h_R1 1 LSTTPSPTSSLHEDGVEDFRR 21 1 O94842-3;O94842-2;O94842;C9J919;C9JNL1 O94842-3 TOX4 TOX high mobility group box family member 4 2 0 LS(0.003)T(0.007)T(0.016)PS(0.851)PT(0.436)S(0.367)S(0.319)LHEDGVEDFRR 57.068 0.011701 45514000 2961.5 2410.6 2159.3 2416.6 3585.3 4968.3 3346.7 3360.8 3139.4 2433.7 TRUE FALSE FALSE 2727.09415 2618.961523 2239.325558 2406.60075 3542.547639 3937.818576 3440.599395 4385.492449 2795.015674 2518.270894 1.08292327 1.039984034 0.889231402 0.955656024 1.406738111 1.563699356 1.36625468 1.741469696 1.109894762 1 11.29821777 -5.65136634 4.223488401 1.022567376 1.530728977 0.851342046 0.104680656 0.058390766 1.867513592 0.014472395 0.029717313 2.23E-06 5.65136634 0.508161601 LSTTPSPTS(ph)S(ph)LHEDGVEDFRR ddPTM_HeLa_Curcumin_4h_R1 1 LSTTPSPTSSLHEDGVEDFRR 21 1 O94842-3;O94842-2;O94842;C9J919;C9JNL1 O94842-3 TOX4 TOX high mobility group box family member 4 2 0 LS(0.001)T(0.002)T(0.004)PS(0.052)PT(0.379)S(0.781)S(0.78)LHEDGVEDFRR 57.708 0.0060666 45500000 2794.9 2221.7 1978.8 2355.8 2852.6 4740.3 3093.3 2722.9 2697.5 2344.1 TRUE FALSE FALSE 2573.680716 2413.733848 2052.136069 2346.052324 2818.584608 3757.108346 3180.089673 3553.099675 2401.590999 2425.557301 1.061067786 0.99512547 0.846047244 0.967221975 1.162035878 1.548967054 1.31107588 1.464859096 0.99011926 1 11.24410055 -5.469117283 4.101447207 1.008603002 1.426074243 0.871275742 0.079241018 0.0616428 2.119376587 0.01186684 0.02692735 3.40E-06 5.469117283 0.417471242 LSVALDGGRS(ph)PDVLSLESR ddPTM_HeLa_Curcumin_4h_R1 1 LSVALDGGRSPDVLSLESR 19 1 Q66GS9 Q66GS9 CEP135 Centrosomal protein of 135 kDa 1 0 LSVALDGGRS(0.987)PDVLS(0.006)LES(0.006)R 53.453 0.014819 2401600 684.27 556.11 455.67 557.98 555.07 797.29 758.61 1016 760.61 756.85 TRUE FALSE FALSE 630.1093075 604.1776704 472.557531 555.6712266 548.4511528 631.9230667 779.8945549 1325.773723 677.172986 783.1504812 0.804582673 0.771470726 0.603405785 0.709533148 0.700313881 0.806898651 0.995842528 1.692872257 0.864677993 1 9.613145736 -4.264772864 2.858000464 0.840526029 1.841330694 0.850199176 0.112657437 0.155121111 1.765159808 0.020843428 0.357404649 5.44E-05 4.264772864 1.000804666 LSVDYGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 LSVDYGKK 8 1 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;P0DPH7-2;F8VQQ4;C9JDS9;P68363;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8 Q9BQE3;P68363;P68366-2 TUBA1C;TUBA1A;TUBA4A;TUBA1B Tubulin alpha-1C chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 1 ; LSVDYGK(1)K;LSVDYGK(1)K 135.83 0.00037004 33115000 11868.8 13230.8 10604.5 9111.9 21792.8 22539 17273.2 15729.1 24465 10676.7 FALSE TRUE FALSE 10929.37196 14374.4114 10997.5121 9074.197372 21532.93509 17864.15733 17757.8395 20524.83018 21781.25071 11047.71453 0.989288049 1.301120821 0.995455854 0.821364215 1.949085038 1.617000266 1.607376752 1.857834951 1.971561688 1 13.43146033 -5.762581068 25 1.009532988 1.73701919 0.355066932 0.337255064 7.757061839 169865.653 0.020712459 0.039134235 1.73E-06 5.762581068 0.727486202 NSESESNKVAAETQS(ph)PSLFGSTK ddPTM_HeLa_Curcumin_4h_R1 1 NSESESNKVAAETQSPSLFGSTK 23 1 Q9UKX7;Q9UKX7-2 Q9UKX7 NUP50 Nuclear pore complex protein Nup50 1 0 NS(0.003)ESESNKVAAET(0.126)QS(0.572)PS(0.287)LFGS(0.009)T(0.003)K 49.394 0.012895 30958000 1795 1181.4 1285.9 1564.3 1371.6 2525.1 2322.1 8330.1 1627.3 1619.5 TRUE FALSE FALSE 1652.923856 1283.514952 1333.556585 1557.827341 1355.244566 2001.365796 2387.251876 10869.90914 1448.789261 1675.777504 0.986362361 0.765922056 0.795783797 0.929614664 0.808725838 1.194290883 1.424563744 6.486487087 0.864547506 1 10.7106149 -4.253423507 3.715703427 0.96225733 7.123244146 0.994192795 0.126860752 0.015471368 0.393266488 0.019445547 0.263974913 5.58E-05 4.253423507 6.160986816 up LSVGEQPDVTHDPYEFLQS(ph)PEPAASAK ddPTM_HeLa_Curcumin_4h_R1 4 LSVGEQPDVTHDPYEFLQSPEPAASAK 27 0 Q9H8M2;Q9H8M2-2;Q9H8M2-3;Q9H8M2-1;Q9H8M2-6 Q9H8M2 BRD9 Bromodomain-containing protein 9 1 0 LSVGEQPDVTHDPY(0.027)EFLQS(0.972)PEPAASAK;LSVGEQPDVTHDPY(0.159)EFLQS(0.84)PEPAAS(0.001)AK;LSVGEQPDVTHDPY(0.253)EFLQS(0.745)PEPAAS(0.002)AK;LSVGEQPDVTHDPY(0.298)EFLQS(0.699)PEPAAS(0.003)AK ;;; 120.31 4.65E-09 101488000 11090.7 9953.8 10881.7 10552.4 11276.7 13228.4 9169.6 4505.84 11262.3 9952.2 TRUE FALSE FALSE 10212.85939 10814.16212 11284.98537 10508.73696 11142.23272 10484.68073 9426.874297 5879.649874 10026.85387 10298.03821 0.991728637 1.050118663 1.095838367 1.020460087 1.081976245 1.018124085 0.915404867 0.570948539 0.973666407 1 13.33008191 -4.260561122 2.420127921 1.015955288 0.467266014 0.927426817 0.038404492 0.113533232 0.798448254 0.005978506 0.129420077 5.49E-05 4.260561122 -0.548689275 LSVGSVT(ph)S(ph)RPSTPTLGTPTPQTMSVSTK ddPTM_HeLa_Curcumin_4h_R1 1 LSVGSVTSRPSTPTLGTPTPQTMSVSTK 28 1 D6RIE8;Q16594 D6RIE8 TAF9 Transcription initiation factor TFIID subunit 9 2 0 LS(0.07)VGS(0.204)VT(0.538)S(0.549)RPS(0.199)T(0.37)PT(0.057)LGT(0.008)PT(0.003)PQTMSVSTK 57.803 0.0055574 17757000 3500.1 2796.8 2766.6 3114.9 2723.6 3058.5 2462.2 1998.2 3384.5 3067 TRUE FALSE FALSE 3223.063392 3038.54293 2869.13263 3102.011369 2691.122849 2424.132624 2531.282705 2607.441981 3013.228818 3173.578022 1.015592927 0.957450206 0.904068723 0.977449222 0.847977529 0.763848441 0.797611619 0.821609541 0.949473685 1 11.6318946 -5.895045229 0.84957264 1.005771159 0.781667748 0.782603794 0.039802619 0.164331602 0.22483858 0.006511491 0.020266581 1.27E-06 5.895045229 -0.224103411 LSVGSVTS(ph)RPSTPTLGTPTPQTMSVSTK ddPTM_HeLa_Curcumin_4h_R1 1 LSVGSVTSRPSTPTLGTPTPQTMSVSTK 28 1 D6RIE8;Q16594 D6RIE8 TAF9 Transcription initiation factor TFIID subunit 9 1 0 LS(0.003)VGS(0.025)VT(0.09)S(0.289)RPS(0.289)T(0.289)PT(0.015)LGTPTPQTMSVSTK 80.212 5.34E-06 27605000 834.34 532.59 634.61 741.35 549.5 645.56 391.63 252.7 668.25 519.97 TRUE FALSE FALSE 768.3011086 578.6247064 658.1292049 738.2824901 542.9475714 511.663579 402.6180838 329.7470667 594.9446469 538.0389188 1.427965676 1.07543281 1.223199999 1.372173024 1.00912323 0.950978751 0.748306618 0.612868429 1.105765078 1 9.071566723 -4.950430768 1.297737782 1.207028743 0.604919283 0.708278159 0.129674404 0.295575048 0.817178587 0.026059957 0.168284792 1.12E-05 4.950430768 -0.60210946 LSVPT(ph)S(ph)DEEDEVPAPKPR ddPTM_HeLa_Curcumin_4h_R1 2 LSVPTSDEEDEVPAPKPR 18 1 Q5STZ8;Q8NE71;Q8NE71-2;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 2 0 LS(0.092)VPT(0.954)S(0.954)DEEDEVPAPKPR;LS(0.007)VPT(0.995)S(0.998)DEEDEVPAPKPR ; 99.796 0.002371 163193000 6478.3 4570.8 5538.7 6200.3 6146 6390 5033.2 3114.86 7591.2 5637.4 TRUE FALSE FALSE 5965.535719 4965.879585 5743.969094 6174.644801 6072.712964 5064.64197 5174.418046 4064.566475 6758.464352 5833.29923 1.022669245 0.85129862 0.984686173 1.058516726 1.041042594 0.868229414 0.887048279 0.696786898 1.158600662 1 12.51009637 -4.169628889 1.008940876 1.001334035 0.508172824 0.605094656 0.078638938 0.928243135 0.645711951 0.009423083 0.515038275 6.77E-05 4.169628889 -0.493161212 LSVPTS(ph)DEEDEVPAPK ddPTM_HeLa_Curcumin_4h_R1 2 LSVPTSDEEDEVPAPK 16 0 Q5STZ8;Q8NE71;Q8NE71-2;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 0 LSVPT(0.038)S(0.961)DEEDEVPAPK;LSVPT(0.233)S(0.767)DEEDEVPAPK ; 197.06 1.47E-07 15154600 8807.4 7183.1 8480.2 9334.2 11026.2 9865 7936.4 9899.7 7392.7 7203.5 TRUE FALSE FALSE 8110.284996 7803.975157 8794.483672 9295.577554 10894.71977 7818.887799 8159.074024 12918.07296 6581.739306 7453.821089 1.088070789 1.046976452 1.179862458 1.247088902 1.461628826 1.048977123 1.094616295 1.733080631 0.883002051 1 12.86376448 -1 0.242571836 1.009978851 3.830030942 0.481360778 0.170558908 34.12514176 0.422279392 0.09511935 39.32129531 0.1 1 2.820052091 LSVPTS(ph)DEEDEVPAPKPR ddPTM_HeLa_Curcumin_4h_R1 3 LSVPTSDEEDEVPAPKPR 18 1 Q5STZ8;Q8NE71;Q8NE71-2;F5GYK6 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 0 LSVPT(0.064)S(0.936)DEEDEVPAPKPR;LSVPT(0.036)S(0.964)DEEDEVPAPKPR;LSVPT(0.086)S(0.914)DEEDEVPAPKPR ;; 184.97 1.37E-07 931385000 13729.1 10618.2 12669.4 14355.1 12376.2 14756.3 11256.2 16424.7 14996.8 12099.5 TRUE FALSE FALSE 12642.42725 11535.98989 13138.93911 14295.7024 12228.6219 11695.67704 11572.01868 21432.51542 13351.68856 12519.95672 1.009782025 0.921408128 1.049439658 1.141833212 0.976730365 0.934162737 0.924285837 1.711868171 1.066432485 1 13.61194196 -4.257690529 24.99945145 1.000720502 1.711868443 0.911722805 0.06620064 71.2370268 475028.6603 0.008663164 0.087088636 5.52E-05 4.257690529 0.71114794 LSVQSNPS(ph)PQLR ddPTM_HeLa_Curcumin_4h_R1 1 LSVQSNPSPQLR 12 0 O75152;E9PBY7;E9PQ61;A0A1W2PPR9 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 0 LS(0.001)VQSNPS(0.998)PQLR 144.51 0.00091496 15951000 1208.8 988.75 809.95 1012.4 847.94 1462.6 1325.8 574.85 1021.5 731.06 TRUE FALSE FALSE 1113.122204 1074.213144 839.9674595 1008.210957 837.8288693 1159.240273 1362.99838 750.1191187 909.4440057 756.4642806 1.471480192 1.420044769 1.110386149 1.332793871 1.107559062 1.532445487 1.801801374 0.99161208 1.202229939 1 9.563128151 -9.400564025 1.057271213 0.994173012 1.3630606 0.127155336 0.232307907 0.579969569 1.130381462 0.163189098 0.039014914 3.98E-10 9.400564025 0.368887588 LSYLSAPGSEYSMYST(ph)DSR ddPTM_HeLa_Curcumin_4h_R1 1 LSYLSAPGSEYSMYSTDSR 19 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 0 LSYLSAPGSEY(0.002)S(0.001)MY(0.006)S(0.035)T(0.629)DS(0.326)R 111.11 0.012017 8745100 1338.4 1472.8 1614.5 1514 1922.3 1737 1556.3 1483.7 1245.6 1377 TRUE FALSE FALSE 1232.464228 1600.102269 1674.33479 1507.735469 1899.377828 1376.72662 1599.965589 1936.0733 1108.960796 1424.850648 0.864977835 1.122996485 1.175094943 1.058170884 1.333036435 0.966225213 1.12290056 1.358790343 0.778299675 1 10.47659499 -7.1547872 5.347421415 0.936537639 1.158959515 0.506661892 0.123970518 0.152371471 6.399277961 0.01881809 0.023128166 7.00E-08 7.1547872 0.222421877 LT(ph)GLGQSNAALR ddPTM_HeLa_Curcumin_4h_R1 2 LTGLGQSNAALR 12 0 Q08378;Q08378-2 Q08378 GOLGA3 Golgin subfamily A member 3 1 0 LT(1)GLGQSNAALR;LT(1)GLGQSNAALR ; 101.53 0.0080211 50501000 6967.3 4216.5 5748.5 5422.6 6136.7 5794.3 5538.6 5199.5 5366.2 6419.8 TRUE FALSE FALSE 6415.830853 4580.955472 5961.544467 5400.162718 6063.523861 4592.496865 5693.99821 6784.803614 4777.541286 6642.887572 0.965819575 0.689603041 0.897432691 0.812923997 0.912784357 0.691340447 0.857157094 1.021363607 0.719196469 1 12.69759478 -7.484119686 21.25925852 0.984920772 0.838388308 0 0.125737261 61.66091477 33821.71605 0.015165761 0.017033157 3.28E-08 7.484119686 -0.146532463 LT(ph)LSEGHPETPVDGDLGK ddPTM_HeLa_Curcumin_4h_R1 1 LTLSEGHPETPVDGDLGK 18 0 E9PDC2;A0A088AWP5;Q8WUY3-4;Q8WUY3;Q8WUY3-2;Q8WUY3-3;H7BZH9 E9PDC2 PRUNE2 Protein prune homolog 2 1 0 LT(0.5)LS(0.5)EGHPETPVDGDLGK 84.166 0.0046852 2381700 4576.4 4096.8 4088.8 4887.9 4820.8 3615.5 2919.4 2495.2 4505.5 4406.9 TRUE FALSE FALSE 4214.173111 4450.909137 4240.334525 4867.675165 4763.315109 2865.604545 3001.310507 3255.974994 4011.257922 4560.039447 0.924152775 0.976068122 0.929889878 1.06746339 1.04457761 0.628416613 0.658176435 0.714023427 0.879654215 1 12.15483059 -5.257736628 24.99199714 0.97427247 0.666002569 0.863188356 0.056130987 76.94897345 519370.0045 0.007552394 0.018474402 5.52E-06 5.257736628 -0.308269901 LT(ph)PEEEEILNK ddPTM_HeLa_Curcumin_4h_R1 2 LTPEEEEILNK 11 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 1 0 LT(1)PEEEEILNK;LT(1)PEEEEILNK ; 199.4 8.53E-29 0 4302.1 3974.3 4403.5 4163.5 4145.5 4173.1 3980.5 4913.2 3819.5 3674.1 TRUE FALSE FALSE 3961.584245 4317.820783 4566.697584 4146.27254 4096.06762 3307.552019 4092.182117 6411.212062 3400.510406 3801.774702 1.042035511 1.135738207 1.201201529 1.090615006 1.077409353 0.870002112 1.076387329 1.686373488 0.894453426 1 11.89245732 -4.264540206 5.349682385 1.040466982 1.710999257 0.804245418 0.095352718 0.043810661 4.518289665 0.012193101 0.107291512 5.44E-05 4.264540206 0.670532275 LT(ph)PSPDIIVLSDNEAS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 2 0 LT(0.765)PS(0.235)PDIIVLS(0.31)DNEAS(0.585)S(0.105)PR 144.57 6.64E-07 0 673.54 535.56 693.96 761.85 699.36 811.57 517.32 620.93 568.86 463.76 TRUE FALSE FALSE 620.2285983 581.85142 719.6787681 758.6976666 691.0205888 643.2412337 531.8346069 810.2486986 506.4574812 479.8756255 1.292477812 1.212504635 1.499719364 1.581029805 1.43999935 1.340433228 1.108275934 1.688455624 1.055393219 1 8.906516725 -8.429130964 0.499429088 0.983998927 1.423448136 0.492390646 0.156180785 0.626802773 0.328216369 0.123537404 0.049411181 3.72E-09 8.429130964 0.439449209 LT(ph)PVRPAAAS(ph)PIVSGAR ddPTM_HeLa_Curcumin_4h_R1 1 LTPVRPAAASPIVSGAR 17 1 I3VM54;Q9Y2K7-3;Q9Y2K7;Q9Y2K7-4;Q9Y2K7-5;Q9Y2K7-2 I3VM54 KDM2A Lysine-specific demethylase 2A 2 0 LT(1)PVRPAAAS(1)PIVSGAR 143.69 0.0012866 18794000 2608.5 2294.6 2171.2 2763.8 2530.2 4209.1 3981.5 1327.3 2842.3 1886 TRUE FALSE FALSE 2402.034473 2492.934999 2251.666582 2752.364128 2500.029018 3336.085214 4093.210174 1731.98766 2530.506801 1951.53836 1.230841536 1.277420445 1.153790583 1.41035615 1.281055535 1.70946433 2.097427475 0.88749865 1.296672847 1 10.93039611 -6.518330948 0.433759116 1.045253129 1.612563746 0.141906102 0.305978711 1.090189474 0.430401855 0.106161076 0.24750271 3.03E-07 6.518330948 0.567310617 LT(ph)PVS(ph)PESSSTEEK ddPTM_HeLa_Curcumin_4h_R1 2 LTPVSPESSSTEEK 14 0 Q13501;E7EMC7;Q13501-2 Q13501 SQSTM1 Sequestosome-1 2 0 LT(1)PVS(0.998)PES(0.001)S(0.001)STEEK;LT(1)PVS(1)PESSSTEEK ; 163.64 0.0010229 13227500 9328.1 8603.3 9368.3 8051.5 8031.9 8102.1 5205 5015.1 9542 8452.9 TRUE FALSE FALSE 8589.771042 9346.930916 9715.497439 8018.185026 7936.124838 6421.633131 5351.038291 6544.180903 8495.266473 8746.637646 0.982065496 1.068631318 1.110769399 0.916716269 0.907334356 0.734183053 0.611782322 0.748193897 0.971260822 1 13.09451281 -5.382666716 1.763784938 1.00442192 0.673283406 0.856492826 0.057245803 0.095389143 0.570168289 0.008522156 0.025781092 4.14E-06 5.382666716 -0.331138514 S(ph)QSLPTTLLS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 1 SQSLPTTLLSPVR 13 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 2 0 S(0.967)QS(0.009)LPT(0.012)T(0.016)LLS(0.996)PVR 111.11 0.0090978 8812000 5449.7 3686.4 3851.4 3767.9 3992.6 5247.4 2502.1 983.37 5147.5 4049.2 TRUE FALSE FALSE 5018.350495 4005.03599 3994.136272 3752.309428 3944.990853 4159.03009 2572.302192 1283.194986 4582.832128 4189.909399 1.197722914 0.955876514 0.953275093 0.895558608 0.941545622 0.992630077 0.613927879 0.306258409 1.093778336 1 12.03270333 -4.343995449 0.97789126 1.061796972 4.44E-32 0.855727366 0.091994549 0.54015096 0.429558099 0.017755224 0.583137538 4.53E-05 4.343995449 -1.061796972 down LTAEDLFEAR ddPTM_HeLa_Curcumin_4h_R1 4 LTAEDLFEAR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ;;; ;;; 144.65 0.0032183 20913500 8396 6995.1 7412.1 7696 8088.6 9209 7335.6 5877.9 7842.3 7406.6 FALSE FALSE TRUE 7731.447741 7599.725274 7686.798946 7664.155991 7992.148728 7298.949593 7541.417193 7670.044651 6982.01931 7663.978799 1.008803383 0.991616166 1.002977585 1.00002312 1.042819786 0.952370797 0.984008097 1.000791476 0.911017566 1 12.90387785 -5.246208311 24.99948988 1.005103611 0.979551926 0 0.034258521 705.109791 1157328.426 0.002244738 0.005687873 5.67E-06 5.246208311 -0.025551686 LTAEEMDER ddPTM_HeLa_Curcumin_4h_R1 2 LTAEEMDER 9 0 P46940;H0YLE8;A0A0J9YXZ5;A0A087X225 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 0 ; ; 163.15 0.0040995 39557000 6577 5102.9 5516.6 5262.6 5528 7248.4 5659.9 4415.5 6776.8 5764.1 FALSE FALSE TRUE 6056.42351 5543.971938 5721.050049 5240.824756 5462.08221 5745.000134 5818.701561 5761.765624 6033.401995 5964.402046 1.015428448 0.929510099 0.959199263 0.878684018 0.915780353 0.963214768 0.975571653 0.966025694 1.011568628 1 12.54216179 -7.26299293 24.99726512 1.007285657 0.940631061 0.564996132 0.027270743 80.06216189 1288229.545 0.004930197 0.005800682 5.46E-08 7.26299293 -0.066654596 LTAGVPDT(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 LTAGVPDTPTR 11 0 P16144-4;P16144-2;P16144-3;P16144 P16144-4 ITGB4 Integrin beta-4 1 0 LTAGVPDT(0.688)PT(0.312)R 116.98 0.013313 13595000 1946.2 2100.3 1989.8 3139.3 2398.4 4081.7 1897.1 1614.9 2865.8 2131.8 TRUE FALSE FALSE 1792.156216 2281.840573 2063.543738 3126.310408 2369.800646 3235.10941 1950.32752 2107.275576 2551.42891 2205.879891 0.812445058 1.034435548 0.935474205 1.4172623 1.074310825 1.466584569 0.884149462 0.955299327 1.156649063 1 11.10713852 -6.474901731 24.98653115 0.92136249 1.158530133 0.122401314 0.192798451 386.0489682 201055.1586 0.027549315 0.042081663 3.35E-07 6.474901731 0.237167643 LTAIIEEAEEAPGARPQLQDAWR ddPTM_HeLa_Curcumin_4h_R1 2 LTAIIEEAEEAPGARPQLQDAWR 23 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 0 0 ; ; 88.471 0.0002201 26198000 1521.26 1226.53 1318.71 1332.22 1134.59 1907.37 1315.75 642.55 1220.67 1224.09 FALSE FALSE TRUE 1400.850666 1332.545788 1367.582553 1326.707627 1121.060755 1511.759962 1352.666404 838.4605371 1086.765555 1266.627036 1.105969339 1.052042748 1.079704217 1.047433529 0.885075656 1.193532049 1.067927942 0.66196324 0.857999651 1 10.30677606 -4.26004691 24.86459067 1.052373082 0.661963103 0.564541601 0.096085518 45.60020796 814166.4946 0.010190185 0.085252252 5.49E-05 4.26004691 -0.390409979 LTALNDSSLDLSMDS(ph)DNS(ph)MSVPSPTSATK ddPTM_HeLa_Curcumin_4h_R1 1 LTALNDSSLDLSMDSDNSMSVPSPTSATK 29 0 G3XAH6;P51003;H0YJL4 G3XAH6 PAPOLA Poly(A) polymerase alpha 2 0 LT(0.008)ALNDS(0.015)S(0.021)LDLS(0.129)MDS(0.446)DNS(0.453)MS(0.321)VPS(0.457)PT(0.064)S(0.084)AT(0.002)K 62.67 0.0011195 0 1323.5 1026.4 1374.7 1389.2 1256.8 1522.6 1369.1 1461.7 1716.4 1089.8 TRUE FALSE FALSE 1218.743578 1115.117442 1425.647591 1383.451858 1241.813481 1206.795597 1407.513261 1907.365601 1528.115214 1127.670469 1.080762166 0.988868178 1.26424131 1.226822815 1.101220184 1.070166888 1.248160079 1.691421079 1.355107947 1 10.13912983 -1.23460233 0.903014459 1.063418022 200 0.588284828 0.128017797 185.8640198 0.62290189 0.015269202 75894.31371 0.058263648 1.23460233 198.936582 LTATPT(ph)PLGGMTGFHMQTEDR ddPTM_HeLa_Curcumin_4h_R1 1 LTATPTPLGGMTGFHMQTEDR 21 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 LT(0.051)AT(0.371)PT(0.573)PLGGMT(0.005)GFHMQTEDR 49.593 0.009709 8545200 1570.1 1306.1 1384.6 1429.2 1602.5 2144.3 1439.9 1263.3 1575.5 1174.6 TRUE FALSE FALSE 1445.824928 1418.993464 1435.914494 1423.286349 1583.391234 1699.548009 1480.299719 1648.474354 1402.671592 1215.417263 1.189570835 1.167494907 1.1814169 1.171026933 1.302755262 1.398324724 1.217935407 1.356303226 1.154065879 1 10.24723597 -12.98771748 0.057630625 2.40E-08 1.733259721 0.558250544 0.071945692 93.95119088 0.470516096 14.47321473 3.339367174 1.03E-13 12.98771748 1.733259697 LTDCVVMRDPASK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 LTDCVVMRDPASKR 14 2 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 1 ; LTDCVVMRDPASK(1)R;LTDCVVMRDPASK(1)R 111.31 0.00031478 67648000 5795.9 6042 4963.3 4461.2 5180 11558.6 7073.4 9230.9 8787.7 5396.1 FALSE TRUE FALSE 5337.148399 6564.243557 5147.244264 4442.740736 5118.231883 9161.216068 7271.860567 12045.35892 7823.711296 5583.614073 0.955859114 1.175626301 0.921848143 0.795674751 0.916652157 1.640732319 1.302357303 2.157269245 1.40119127 1 12.44698351 -3.552204953 0.747156333 0.973101769 4.54565856 0.667449976 0.228914356 2.096502321 0.392615233 0.028622871 8.06863024 0.000280411 3.552204953 3.572556791 LTDS(ph)SPSSTSTSNSQR ddPTM_HeLa_Curcumin_4h_R1 1 LTDSSPSSTSTSNSQR 16 0 Q5VT06 Q5VT06 CEP350 Centrosome-associated protein 350 1 0 LT(0.01)DS(0.344)S(0.256)PS(0.11)S(0.11)T(0.11)S(0.026)T(0.026)S(0.008)NS(0.002)QR 101.2 0.003539 0 2206.1 1663 1713.9 1620.6 2032.2 2830.5 2063.9 847.68 2118.8 1816.5 TRUE FALSE FALSE 2031.484857 1806.74231 1777.418642 1613.894387 2007.967342 2243.422394 2121.807479 1106.13373 1886.372941 1879.62324 1.080793647 0.961225777 0.945624955 0.858626533 1.068281824 1.193548976 1.128847226 0.588486941 1.003590986 1 10.8762278 -7.244476379 23.51811403 1.038152558 0.978032931 0.027290601 0.157842355 1252.64901 1736715.437 0.025775597 0.031516366 5.70E-08 7.244476379 -0.060119628 LTDSS(ph)PSSTSTSNSQR ddPTM_HeLa_Curcumin_4h_R1 1 LTDSSPSSTSTSNSQR 16 0 Q5VT06 Q5VT06 CEP350 Centrosome-associated protein 350 1 0 LT(0.003)DS(0.015)S(0.249)PS(0.249)S(0.249)T(0.071)S(0.071)T(0.071)S(0.02)NS(0.002)QR 108.06 0.0017742 7984800 1504.8 1307.6 1409.2 1394.1 1415.3 1791.9 1351.2 1064.7 1512.8 1270 TRUE FALSE FALSE 1385.693492 1420.623117 1461.426192 1388.331584 1398.423472 1420.239741 1389.111035 1389.322129 1346.849625 1314.132405 1.054455005 1.081034994 1.112084433 1.056462483 1.064141989 1.080743261 1.057055613 1.057216246 1.024896441 1 10.35989493 -8.521469928 0.761618421 1.003476473 1.072183411 0.622076438 0.017902411 0.24821377 0.29668485 0.008478879 0.004042795 3.01E-09 8.521469928 0.068706938 LTEDLEYHELLDR ddPTM_HeLa_Curcumin_4h_R1 4 LTEDLEYHELLDR 13 0 P22059;H0YCV6 P22059 OSBP Oxysterol-binding protein 1 0 0 ;;; ;;; 255.24 3.32E-36 20746800 12096.2 10356.8 10682.6 11025.2 9719.58 12792.9 9627.09 7130.83 11757.4 10807.1 FALSE FALSE TRUE 11138.77301 11251.99564 11078.50655 10979.58064 9603.680357 10139.50833 9897.200235 9304.987241 10467.64264 11182.64592 0.996076696 1.006201549 0.990687413 0.981841035 0.85880215 0.906718178 0.885049952 0.832091735 0.93606135 1 13.44897396 -5.814807937 5.337606218 0.997690709 0.874151229 0.808504245 0.026912692 0.037324841 2.248770683 0.002622685 0.004885752 1.53E-06 5.814807937 -0.123539481 LTEGCS(ph)FR ddPTM_HeLa_Curcumin_4h_R1 2 LTEGCSFR 8 0 P42677;H0YMV8;Q71UM5;C9J1C5 P42677 RPS27;RPS27L 40S ribosomal protein S27;40S ribosomal protein S27-like 1 0 LTEGCS(1)FR;LTEGCS(1)FR ; 108.43 0.011753 329610000 14618.2 9396.8 7226.2 9005.6 8528.6 9899.1 11749.3 7817.2 10238.5 7276.8 TRUE FALSE FALSE 13461.15404 10209.01752 7494.009329 8968.337213 8426.902015 7845.915074 12078.95374 10200.62829 9115.362165 7529.668258 1.787748621 1.355838952 0.99526421 1.191066712 1.119159799 1.042000099 1.604181396 1.354724796 1.210592798 1 12.87837059 -6.971380621 24.94871582 1.382508331 1.217779225 0.044671858 0.244744474 539.001441 469869.1171 0.054009974 0.070982353 1.07E-07 6.971380621 -0.164729106 LTEGCSFR ddPTM_HeLa_Curcumin_4h_R1 2 LTEGCSFR 8 0 P42677;H0YMV8;Q71UM5;C9J1C5 P42677 RPS27;RPS27L 40S ribosomal protein S27;40S ribosomal protein S27-like 0 0 ; ; 119.17 0.0028152 16442700 4003 2656.3 3439.2 3141 3181.5 4017.6 3075.1 2452.1 3949.6 3659.1 FALSE FALSE TRUE 3686.158326 2885.898736 3566.659777 3128.003374 3143.56269 3184.304472 3161.37903 3199.734002 3516.338761 3786.253453 0.973563543 0.762204319 0.942002384 0.826147381 0.830256804 0.841017252 0.834962337 0.845092396 0.928711933 1 11.88655527 -7.375372311 6.726948357 0.988333514 0.843249337 0.613555731 0.045411026 0.084829258 4.483105097 0.00653535 0.007448122 4.21E-08 7.375372311 -0.145084177 LTEMETLQSQLMAEK ddPTM_HeLa_Curcumin_4h_R1 1 LTEMETLQSQLMAEK 15 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 248.77 2.58E-29 11254000 868 801.92 752.46 708.75 783.38 857.18 837.78 608.1 954.67 665.06 FALSE FALSE TRUE 799.2968841 871.2343915 780.3468295 705.8173803 774.0387051 679.3912056 861.285852 793.5068907 849.9450895 688.1707855 1.161480407 1.266014789 1.133943559 1.025642755 1.124777049 0.98724215 1.251558291 1.153066808 1.235078715 1 9.426622837 -9.25059158 1.037966574 1.001793907 1.137056034 0 0.108402166 0.542546199 1.068915378 0.05198495 0.015036807 5.62E-10 9.25059158 0.135262126 TEEARPSPAPGPGTPT(ph)GT(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 TEEARPSPAPGPGTPTGTPTR 21 1 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 2 0 T(0.015)EEARPS(0.008)PAPGPGT(0.301)PT(0.632)GT(0.735)PT(0.309)R 65.118 0.003328 39377000 2797.8 2530.8 2468.7 2745.5 2980.1 3501.7 1984 758.79 2966.7 2103.6 TRUE FALSE FALSE 2576.351178 2749.551075 2560.192194 2734.139848 2944.564254 2775.407948 2039.6657 990.141578 2641.260432 2176.699943 1.183604192 1.263174138 1.176180576 1.25609405 1.352765347 1.275053071 0.937044955 0.454881979 1.213424221 1 11.08792683 -4.34321657 2.934291537 1.148141602 0.397079596 0.815071921 0.107306327 0.135356093 1.782222427 0.01919394 0.214484052 4.54E-05 4.34321657 -0.751062006 down LTEVPVEPVLTVHPES(ph)K ddPTM_HeLa_Curcumin_4h_R1 2 LTEVPVEPVLTVHPESK 17 0 Q9H307 Q9H307 PNN Pinin 1 0 LTEVPVEPVLT(0.008)VHPES(0.992)K;LTEVPVEPVLTVHPES(1)K ; 175.77 7.66E-06 12961400 10796.3 8696.7 9457 9863.5 10329.8 17382.1 17385.7 11083.6 11371.4 9412.6 TRUE FALSE FALSE 9941.761463 9448.403996 9807.484739 9822.68745 10206.62388 13776.85652 17873.49595 14462.93862 10123.98587 9739.687149 1.020747516 0.970093172 1.006960962 1.008521865 1.047941656 1.41450709 1.83512013 1.484948992 1.039456988 1 13.24965972 -5.130342366 2.887882514 1.007097902 1.659606529 0.908892247 0.084053316 0.04380292 0.69686605 0.010197942 0.030605575 7.41E-06 5.130342366 0.652508627 LTEVQDDKEEEEEENPLLVPLEEK ddPTM_HeLa_Curcumin_4h_R1 2 LTEVQDDKEEEEEENPLLVPLEEK 24 1 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 0 0 ; ; 85.7 0.00012496 10388600 3453.8 2453.71 2774.8 2738.61 3070 2274.4 1934.33 1543.09 2612.1 2898.6 FALSE FALSE TRUE 3180.428086 2665.797759 2877.636529 2727.278357 3033.392255 1802.663802 1988.602094 2013.571037 2325.559165 2999.326134 1.06038088 0.888798897 0.959427685 0.909297034 1.011357925 0.601022937 0.663016293 0.671341144 0.775360551 1 11.55042269 -5.265107124 24.99852153 1.002904314 0.646915731 0.664880769 0.090440141 76.90098951 524141.7791 0.009159711 0.021258097 5.43E-06 5.265107124 -0.355988583 LTFDSS(ph)FSPNTGKK ddPTM_HeLa_Curcumin_4h_R1 1 LTFDSSFSPNTGKK 14 1 C9JI87;P21796 C9JI87 VDAC1 Voltage-dependent anion-selective channel protein 1 1 0 LT(0.06)FDS(0.274)S(0.665)FS(0.001)PNTGKK 145.49 0.0009887 40899000 3835.7 2742.4 3921.4 3586.7 4607.5 8768.9 4867.5 2775.4 4794 3467.4 TRUE FALSE FALSE 3532.100298 2979.440836 4066.730534 3571.859186 4552.558572 6950.131294 5004.06895 3621.606684 4268.110194 3587.891892 0.984450035 0.830415443 1.133459607 0.995531441 1.268867265 1.937107222 1.394710069 1.009396825 1.189587179 1 11.80892071 -5.620914945 4.219355519 0.991336695 1.464138754 0.405754319 0.229343737 0.134107121 4.357179631 0.031055466 0.064225511 2.39E-06 5.620914945 0.47280206 LTFSCLGGSDNFK ddPTM_HeLa_Curcumin_4h_R1 1 LTFSCLGGSDNFK 13 0 A0A087WYT3;Q15185-4;Q15185;Q15185-2;Q15185-3 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 0 0 169.65 6.85E-06 878260 377.12 221.26 377.61 315.39 386.51 612.78 342.46 393.31 287.04 348.11 FALSE FALSE TRUE 347.2705541 240.3847285 391.6045588 314.0849997 381.9011207 485.6825205 352.0685059 513.2284084 255.5524301 360.2067966 0.964086623 0.667352007 1.087165935 0.87195745 1.060227415 1.348343577 0.977406615 1.424816004 0.709460323 1 8.492681593 -5.4902836 6.246543057 0.958188169 1.221491893 0.448832351 0.170118437 0.14117588 17.19663702 0.019827729 0.043629328 3.23E-06 5.4902836 0.263303723 LTGIKHELQANCYEEVKDR ddPTM_HeLa_Curcumin_4h_R1 2 LTGIKHELQANCYEEVKDR 19 2 P23528;G3V1A4;E9PP50;E9PK25 P23528 CFL1 Cofilin-1 0 0 ; ; 52.42 0.012769 224490000 11059.3 7506.8 8388.3 8882 7819.8 12087.8 8354.3 7637.8 11795.5 10051.5 FALSE FALSE TRUE 10183.94474 8155.654342 8699.177777 8845.248637 7726.553992 9580.654022 8588.699174 9966.53006 10501.56316 10400.78888 0.979151183 0.784138053 0.836395958 0.850440168 0.742881534 0.921146861 0.825773821 0.958247512 1.0096891 1 13.34440534 -7.329916021 7.27578211 0.990512797 0.843708183 0.584666033 0.058148038 0.131362003 12.2888834 0.009290343 0.010608316 4.68E-08 7.329916021 -0.146804614 LTGS(ph)TSSLNK ddPTM_HeLa_Curcumin_4h_R1 2 LTGSTSSLNK 10 0 Q9NV70-2;Q9NV70 Q9NV70-2 EXOC1 Exocyst complex component 1 1 0 LT(0.003)GS(0.83)T(0.041)S(0.097)S(0.029)LNK;LT(0.001)GS(0.672)T(0.241)S(0.025)S(0.061)LNK ; 121.29 0.0043436 33111000 6789.9 6087.5 6174 6427.5 6120 7712.9 5518.1 5701.2 8044.9 6313.5 TRUE FALSE FALSE 6252.47225 6613.676375 6402.813871 6400.904708 6047.022997 6113.157598 5672.923035 7439.469635 7162.394597 6532.893655 0.957075468 1.012365534 0.980088489 0.97979625 0.925627037 0.935750361 0.868362985 1.138770969 1.09635867 1 12.67350644 -5.960286736 24.92947429 0.982108084 0.957191898 0 0.075655241 490.0136381 307597.4243 0.009057655 0.016418374 1.10E-06 5.960286736 -0.024916185 LTGSTS(ph)SLNK ddPTM_HeLa_Curcumin_4h_R1 1 LTGSTSSLNK 10 0 Q9NV70-2;Q9NV70 Q9NV70-2 EXOC1 Exocyst complex component 1 1 0 LTGS(0.001)T(0.097)S(0.692)S(0.21)LNK 155.26 0.00064191 33892000 3860.6 3107.8 3054.4 2981.5 3157.4 3026.9 2395.9 1396.5 3477.6 2953.8 TRUE FALSE FALSE 3555.029436 3376.424384 3167.598751 2969.163343 3119.750067 2399.08682 2463.122506 1822.286421 3096.115981 3056.44433 1.163125859 1.104690293 1.036367232 0.97144362 1.020712217 0.784927373 0.805878413 0.596211226 1.012979674 1 11.57763857 -4.756440028 0.754236913 1.079502648 0.51313029 0.859209988 0.06072569 0.460633688 0.278087364 0.012338764 0.189995582 1.75E-05 4.756440028 -0.566372358 LTGSTSS(ph)LNK ddPTM_HeLa_Curcumin_4h_R1 2 LTGSTSSLNK 10 0 Q9NV70-2;Q9NV70 Q9NV70-2 EXOC1 Exocyst complex component 1 1 0 LTGS(0.001)T(0.354)S(0.188)S(0.458)LNK;LTGS(0.082)T(0.084)S(0.294)S(0.54)LNK ; 181.31 0.000282 98213000 8098 6966.5 8351 7033.2 7220.7 7104.7 5921.6 3047.2 7741.7 6915.6 TRUE FALSE FALSE 7457.034755 7568.653218 8660.495406 7004.098482 7134.597868 5631.105134 6087.744159 3976.277252 6892.454879 7155.916585 1.042079609 1.057677675 1.210256618 0.978784255 0.997020827 0.786915983 0.850728776 0.555662885 0.963182675 1 12.80492086 -4.316471088 0.828538651 1.036874888 0.350576322 0.779531919 0.079286994 0.744182239 0.388657338 0.01233088 0.458063785 4.83E-05 4.316471088 -0.686298566 (ac)ADKPDMGEIASFDK(ac)AK ddPTM_HeLa_Curcumin_4h_R1 1 ADKPDMGEIASFDKAK 16 2 P63313 P63313 TMSB10 Thymosin beta-10 0 1 ADKPDMGEIASFDK(1)AK 91.858 7.34E-45 0 529.71 443.29 476.04 371.01 329.13 770.41 672.63 1117.8 474.61 392.41 FALSE TRUE FALSE 487.7828946 481.6060123 493.6824612 369.4748589 325.2053397 610.6182817 691.5021875 1458.612074 422.5464704 406.0462183 1.201298947 1.186086683 1.215828245 0.909933013 0.8009072 1.503814724 1.70301349 3.592231644 1.040636389 1 8.665500142 -3.994994711 1.395237621 1.087163796 6.150111457 0.954984684 0.163155646 0.338971623 0.360077811 0.024595918 2.865579817 0.000101159 3.994994711 5.062947661 up LTLDKLDVK ddPTM_HeLa_Curcumin_4h_R1 1 LTLDKLDVK 9 1 P00558 P00558 PGK1 Phosphoglycerate kinase 1 0 0 70.552 0.0204 0 8137.3 5006.7 7199.3 5961.7 5851.7 8256.1 7511 7983 7100.3 6354.7 FALSE FALSE TRUE 7493.224119 5439.456839 7466.112391 5937.032065 5781.922299 6543.691795 7721.738445 10416.97995 6321.414854 6575.525352 1.139562806 0.827227719 1.135439678 0.902898513 0.879309559 0.995158781 1.17431506 1.584204971 0.961355103 1 12.68289045 -4.302127372 2.592981829 1.02678795 1.672268055 0.747186617 0.104133946 0.183512501 1.675485442 0.015534572 0.246263636 4.99E-05 4.302127372 0.645480105 LTLEDLEDSWDR ddPTM_HeLa_Curcumin_4h_R1 2 LTLEDLEDSWDR 12 0 Q6P2Q9;I3L3Z8 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 0 ; ; 308.92 9.45E-87 18267100 3604 2937.1 3174.9 2996.6 3469.6 4463.5 3087.2 2643.9 3894.6 3400 FALSE FALSE TRUE 3318.739597 3190.969837 3292.564587 2984.200863 3428.227286 3537.719786 3173.818523 3450.012939 3467.372124 3518.149747 0.943319596 0.907002278 0.935879603 0.8482302 0.974440411 1.005562594 0.902127184 0.980632772 0.985566952 1 11.78060118 -8.79503436 0.865246228 0.997083514 0.936079524 0.209799177 0.042724195 0.618429953 0.90803259 0.021132903 0.008639915 1.60E-09 8.79503436 -0.06100399 LTLEGLEEDDDDRVS(ph)PTVLHK ddPTM_HeLa_Curcumin_4h_R1 1 LTLEGLEEDDDDRVSPTVLHK 21 1 Q9NPB8 Q9NPB8 GPCPD1 Glycerophosphocholine phosphodiesterase GPCPD1 1 0 LTLEGLEEDDDDRVS(0.655)PT(0.345)VLHK 89.507 0.00020214 5641400 4076.3 3220.2 4118.6 3777.4 3699.3 3148 2837.5 3188 4063 3682.5 TRUE FALSE FALSE 3753.656554 3498.539739 4271.238939 3761.77012 3655.188264 2495.069315 2917.112613 4160.006524 3617.299065 3810.466601 0.985091052 0.918139458 1.120922812 0.987220336 0.959249521 0.654793645 0.7655526 1.091731528 0.949306068 1 11.89575195 -5.499472267 23.89430692 0.995920391 0.826319049 0.275841473 0.112966939 370.441998 378161.631 0.014978085 0.033268302 3.17E-06 5.499472267 -0.169601341 SQSSEGVSSLSSS(ph)PSNSLETQSQSLSR ddPTM_HeLa_Curcumin_4h_R1 1 SQSSEGVSSLSSSPSNSLETQSQSLSR 27 0 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 0 SQSSEGVSSLSS(0.223)S(0.775)PS(0.001)NSLETQSQSLSR 178.46 4.05E-15 55756000 3207.4 2838 2938.5 3027.5 2767.4 3187.5 1780.4 632.52 3214.3 2712.6 TRUE FALSE FALSE 2953.530906 3083.304074 3047.403395 3014.973007 2734.400562 2526.376569 1830.353232 825.3724362 2861.699332 2806.862648 1.05225345 1.098487693 1.08569737 1.074143407 0.974183957 0.90007132 0.652099323 0.294055157 1.019536647 1 11.45474275 -4.342852116 1.175763393 1.039155773 0.006147901 0.981052736 0.033251245 0.152866298 0.190316647 0.006201017 0.185639856 4.54E-05 4.342852116 -1.033007872 down ADALQAGASQFETS(ph)AAK ddPTM_HeLa_Curcumin_4h_R1 1 ADALQAGASQFETSAAK 17 0 Q15836;K7ENK9;K7EKX0;J3QRU4;F8WCA0;L7N2F9;P63027 Q15836 VAMP3;VAMP2 Vesicle-associated membrane protein 3;Vesicle-associated membrane protein 2 1 0 ADALQAGASQFET(0.201)S(0.799)AAK 146.88 0.00026305 4741200 1530.5 1526.1 1637.2 1773.2 1706.1 2480.5 1276.8 508.46 1824.2 1515.3 TRUE FALSE FALSE 1409.35931 1658.009284 1697.876072 1765.862968 1685.755872 1966.016339 1312.623572 663.4871133 1624.089824 1567.956562 0.898850991 1.057433174 1.082859126 1.126219317 1.075129192 1.253871686 0.837155571 0.423154014 1.035800266 1 10.61466988 -4.341941058 3.484579045 1.006354837 0.395990307 0.771324747 0.102850027 0.107845977 2.140704202 0.016613002 0.148820432 4.55E-05 4.341941058 -0.61036453 down FSSVS(ph)SPQPR ddPTM_HeLa_Curcumin_4h_R1 1 FSSVSSPQPR 10 0 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 1 0 FS(0.006)S(0.035)VS(0.709)S(0.25)PQPR 112.85 0.0063816 79634000 7324.4 5649.4 5601.6 5592.5 5562.1 5511.1 3868.8 1867.1 6952.6 5543.5 TRUE FALSE FALSE 6744.666011 6137.708963 5809.200224 5569.359717 5495.77559 4368.035737 3977.348116 2436.370195 6189.917175 5736.136212 1.175820406 1.070007534 1.012737496 0.97092529 0.958097121 0.761494423 0.693384531 0.424740645 1.079109168 1 12.48586357 -4.33882196 0.637536629 1.082840339 0.065539363 0.944958434 0.049976719 0.638926945 0.188027592 0.012886287 0.463319863 4.58E-05 4.33882196 -1.017300976 down LTLYDIAHTPGVAADLSHIETK ddPTM_HeLa_Curcumin_4h_R1 1 LTLYDIAHTPGVAADLSHIETK 22 0 P40926;P40926-2 P40926 MDH2 "Malate dehydrogenase, mitochondrial" 0 0 71.756 0.00062272 13035000 4002 2869.1 3616 3156.5 3574.4 4581.8 3763.7 3235 3841.7 2904.9 FALSE FALSE TRUE 3685.237477 3117.09222 3750.012141 3143.439239 3531.777615 3631.483032 3869.299293 4221.336608 3420.275121 3005.845059 1.226023765 1.037010278 1.247573334 1.04577554 1.174969949 1.20814046 1.287258397 1.404375983 1.137874726 1 11.55355493 -1 0.024350429 3.01E-14 2.799964741 0.412995375 0.091263787 1249.984922 2.365290472 94.94207255 193.5458737 0.1 1 2.799964741 LTNENLDLK ddPTM_HeLa_Curcumin_4h_R1 1 LTNENLDLK 9 0 A0A0A0MR36;Q9ULV0-2;Q9ULV0 A0A0A0MR36 MYO5B Unconventional myosin-Vb 0 0 163.15 0.0040995 124910000 2594.4 2236.7 2526 2684.9 2534.8 2657.2 2561.1 1368.9 2637.2 1916.6 FALSE FALSE TRUE 2389.050502 2430.030381 2619.615782 2673.790595 2504.574166 2106.066767 2632.957573 1786.271308 2347.905758 1983.201707 1.204643226 1.225306721 1.320902343 1.348219188 1.262894317 1.061952881 1.327629743 0.900700772 1.1838966 1 10.9536157 -8.93546338 0.814386339 1.00287362 1.216126087 0.035150758 0.140194327 0.605758256 0.752708404 0.075068364 0.02523387 1.16E-09 8.93546338 0.213252467 LTNHGK(ac)TGNGGAQSQHQNVNQGPTCNVGSK(ac)GVGAGNHGAK ddPTM_HeLa_Curcumin_4h_R1 1 LTNHGKTGNGGAQSQHQNVNQGPTCNVGSKGVGAGNHGAK 40 2 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0;E9PNR0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 0 2 LTNHGK(1)TGNGGAQSQHQNVNQGPTCNVGSK(1)GVGAGNHGAK 98.667 7.62E-15 2346700 367.17 147.77 193.96 221.95 562.95 1112 348.15 266.93 326.98 353.62 FALSE TRUE FALSE 338.1081071 160.5425803 201.1483282 221.0316297 556.2371889 881.3586652 357.918152 348.3157282 291.1111121 365.9082687 0.924024232 0.438750895 0.549723375 0.604062954 1.52015474 2.408687479 0.978163607 0.951920899 0.795584951 1 8.515338207 -5.74767484 24.59451717 0.862469218 1.497402487 0.405617384 0.42064423 178.3993408 318761.9011 0.063787549 0.127015247 1.79E-06 5.74767484 0.634933269 LTPAEEENNSFQRLS(ph)P ddPTM_HeLa_Curcumin_4h_R1 1 LTPAEEENNSFQRLSP 16 1 Q5HYI7-5;Q5HYI7 Q5HYI7-5 MTX3 Metaxin-3 1 0 LTPAEEENNS(0.169)FQRLS(0.831)P 113.67 0.012895 25530000 3376 2986 3172.9 2814.9 2567.3 3312.5 2569.2 6192.8 3489.7 3262.4 TRUE FALSE FALSE 3108.786038 3244.096535 3290.490465 2803.25269 2536.686624 2625.45016 2641.284837 8080.956212 3106.888641 3375.768157 0.920912187 0.960995064 0.974738285 0.830404388 0.751439822 0.777734145 0.782424833 2.393812559 0.920350124 1 11.72100011 -4.258227478 24.99716113 0.91841567 2.393813104 0.959923126 0.092500289 49.66370903 386497.5066 0.015209 0.145587416 5.52E-05 4.258227478 1.475397435 LTPATK(ac)MNNK ddPTM_HeLa_Curcumin_4h_R1 1 LTPATKMNNK 10 1 O14497;O14497-2;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497 ARID1A AT-rich interactive domain-containing protein 1A 0 1 LTPATK(1)MNNK 136.52 0.0005555 3457800 2322.5 1611.1 1822.8 2193.4 1770.7 2186.1 1062.5 1179.9 2652.5 2282.9 FALSE TRUE FALSE 2138.671674 1750.356305 1890.354571 2184.324292 1749.585559 1732.678218 1092.31089 1539.646078 2361.527386 2362.230605 0.90536109 0.740976051 0.800241334 0.924687153 0.740649772 0.733492409 0.462406544 0.651776366 0.999702307 1 11.20593409 -3.604835572 0.211667995 1.023434978 1.32E-11 0.711439187 0.085567054 6.441139212 0.19787298 0.08488377 1.816027541 0.000248407 3.604835572 -1.023434978 LTPEEEEILNK ddPTM_HeLa_Curcumin_4h_R1 2 LTPEEEEILNK 11 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 0 ; ; 174.86 2.37E-09 7315700 2794.3 2552 3002.2 3339.6 2888.6 1134.87 1360.88 1226.15 3055.2 2749.9 FALSE FALSE TRUE 2573.128206 2772.583509 3113.464173 3325.78162 2854.155332 899.4851694 1399.06263 1599.99749 2720.052204 2845.45882 0.904292899 0.974388907 1.094187043 1.168803286 1.003056277 0.316112524 0.491682614 0.562298593 0.955927453 1 11.47444559 -5.270004564 24.8854634 0.985306894 0.460196378 0.88296673 0.092616847 153.4151559 445735.9154 0.014864197 0.033735165 5.37E-06 5.270004564 -0.525110516 LTPEELER ddPTM_HeLa_Curcumin_4h_R1 1 LTPEELER 8 0 Q5H8X8;O95399;O95399-2 Q5H8X8 UTS2 Urotensin-2 0 0 98.629 0.014671 6108000 4228.7 3332.6 4443.8 4363 4250.8 4754.3 3406 2880.5 4247.5 3759 FALSE FALSE TRUE 3893.993933 3620.655094 4608.491137 4344.947062 4200.111986 3768.204588 3501.563193 3758.75119 3781.559877 3889.62497 1.001123235 0.930849406 1.184816318 1.117060667 1.079824409 0.968783525 0.90023157 0.966353111 0.972217092 1 11.92541534 -5.009804135 19.09601948 1.022948286 0.933595723 0.253474223 0.072483323 24.99555694 48697.34192 0.010684289 0.029522928 9.78E-06 5.009804135 -0.089352564 LTPIHDR ddPTM_HeLa_Curcumin_4h_R1 2 LTPIHDR 7 0 P28072;I3L3X7;A0A087X2I4 P28072 PSMB6 Proteasome subunit beta type-6;Proteasome subunit beta type 0 0 ; ; 135.77 0.0039609 10296400 9463.4 8634.1 10217.5 8066.4 11889 14407.7 11908.2 10860.1 9495.4 8117.1 FALSE FALSE TRUE 8714.361904 9380.393131 10596.16954 8033.023374 11747.23144 11419.38061 12242.31204 14171.2945 8453.778376 8399.168621 1.037526724 1.116824004 1.261573617 0.956406966 1.39861836 1.359584636 1.457562361 1.68722586 1.006501805 1 13.03603082 -1.13268243 0.288790684 0.9893788 6.282150997 0.826423785 0.09632845 11.22372175 0.154005286 0.035913941 30.29019184 0.073674563 1.13268243 5.292772197 LTPLPEDNSMNVDQDGDPSDR ddPTM_HeLa_Curcumin_4h_R1 1 LTPLPEDNSMNVDQDGDPSDR 21 0 P78527-2;P78527 P78527-2 PRKDC DNA-dependent protein kinase catalytic subunit 0 0 95.981 0.0015313 6933600 1123.1 1322.8 1273.3 1385 1383.8 1322.1 1043.8 787.61 1162.6 1056.5 FALSE FALSE TRUE 1034.20545 1437.136938 1320.489618 1379.269237 1367.299089 1047.881557 1073.086219 1027.748663 1035.065689 1093.213296 0.946023483 1.314598846 1.20789751 1.261665259 1.250715751 0.958533491 0.981589066 0.940117237 0.946810373 1 10.0943592 -7.350225891 24.99999962 0.974510826 1.131008748 0.26348388 0.127185138 78.02188254 21966.63714 0.023542393 0.026921644 4.46E-08 7.350225891 0.156497922 LTPLSHEVISR ddPTM_HeLa_Curcumin_4h_R1 2 LTPLSHEVISR 11 0 H7BZU1;Q2VIR3-2;Q2VIR3;P41091 H7BZU1 EIF2S3;EIF2S3L Putative eukaryotic translation initiation factor 2 subunit 3-like protein;Eukaryotic translation initiation factor 2 subunit 3 0 0 ; ; 136.81 9.32E-05 7544500 3642.9 3186.7 3237.9 3213.6 4081.8 4870.7 3431.7 3261.4 3934.1 3498.2 FALSE FALSE TRUE 3354.560621 3462.144148 3357.899422 3200.302975 4033.127201 3860.461916 3527.984266 4255.785846 3502.539073 3619.76219 0.926735085 0.956456244 0.927657467 0.884119676 1.114196732 1.066496005 0.974645317 1.175708686 0.967615796 1 11.8216792 -5.752054637 24.99997248 0.955625944 1.07387726 0.595251054 0.055443986 126.8996202 338044.8098 0.008231131 0.016287696 1.77E-06 5.752054637 0.118251316 LTPPS(ph)PVRSEPQPAVPQELEMPVLK ddPTM_HeLa_Curcumin_4h_R1 1 LTPPSPVRSEPQPAVPQELEMPVLK 25 1 Q8TAP8 Q8TAP8 PPP1R35 Protein phosphatase 1 regulatory subunit 35 1 0 LT(0.065)PPS(0.884)PVRS(0.051)EPQPAVPQELEMPVLK 63.398 0.001222 17231000 2580 1982.2 2415.7 2165.3 2518.3 4086 2895.2 1567.6 2811.8 2513.4 TRUE FALSE FALSE 2375.790278 2153.532535 2505.227967 2156.340562 2488.270917 3238.517541 2976.43152 2045.554024 2503.352575 2600.740463 0.913505331 0.828045922 0.963274884 0.829125625 0.956754798 1.245229037 1.14445542 0.78652755 0.962553784 1 11.34470672 -5.491128904 24.678208 0.937632716 1.072922965 0.203318983 0.120980185 679.672377 528288.4164 0.016924893 0.037807411 3.23E-06 5.491128904 0.135290249 LTPS(ph)PDIIVLSDNEAS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 2 0 LT(0.004)PS(0.96)PDIIVLS(0.036)DNEAS(0.739)S(0.261)PR 146.28 0.00029137 11203000 2148.5 2045.4 2030.1 2175.2 2066.1 3210.6 2350.7 3041.1 2176.2 2127.9 TRUE FALSE FALSE 1978.443958 2222.195262 2105.337292 2166.199599 2041.463107 2544.685369 2416.654315 3968.31739 1937.476305 2201.844367 0.898539419 1.009242658 0.956169893 0.983811404 0.927160492 1.155706283 1.097559097 1.802269702 0.879933357 1 11.10449678 -1.610497202 0.992864892 0.95776653 200 0.934229631 0.065846021 61.47662242 0.329621999 0.009270919 27516.17681 0.024519002 1.610497202 199.0422335 LTPS(ph)PDIIVLSDNEASSPR ddPTM_HeLa_Curcumin_4h_R1 4 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 0 LTPS(0.999)PDIIVLS(0.001)DNEASSPR;LTPS(0.998)PDIIVLS(0.001)DNEASSPR;LTPS(1)PDIIVLSDNEASSPR;LT(0.038)PS(0.93)PDIIVLS(0.032)DNEASSPR ;;; 185.96 9.69E-08 31019800 5201.52 4927.54 4236.21 4488.21 5207.7 7791.5 5801.22 5400.4 6296.4 4626 TRUE FALSE FALSE 4789.814203 5353.454601 4393.207669 4469.638976 5145.601579 6175.455072 5963.98662 7046.9571 5605.700673 4786.753156 1.000639483 1.118389528 0.917784462 0.933751717 1.074966979 1.290113543 1.245935695 1.472178922 1.171086223 1 12.2248317 -5.135842043 1.595508085 0.998242816 1.383899288 0.714436286 0.089040474 0.116887989 0.549048048 0.009980018 0.041150681 7.31E-06 5.135842043 0.385656473 LTPSPDIIVLS(ph)DNEASSPR ddPTM_HeLa_Curcumin_4h_R1 5 LTPSPDIIVLSDNEASSPR 19 0 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 1 0 LTPSPDIIVLS(0.999)DNEASSPR;LTPSPDIIVLS(1)DNEASSPR;LTPSPDIIVLS(1)DNEASSPR;LTPSPDIIVLS(1)DNEASSPR;LTPSPDIIVLS(1)DNEASSPR ;;;; 287 8.13E-83 46918200 5396.14 4159.05 4740.65 4970.57 4860.26 6213.2 4328.95 6770.83 5105.56 4570.07 TRUE FALSE FALSE 4969.029825 4518.53975 4916.342659 4950.003098 4802.304574 4924.512283 4450.408686 8835.224898 4545.492841 4728.879592 1.050783749 0.955520153 1.039642174 1.046760232 1.01552693 1.041369776 0.94111271 1.868354803 0.961219831 1 12.20728269 -4.258249784 24.99990163 1.018878706 1.868355115 0.975917782 0.040603393 27.53334958 215794.583 0.004871962 0.046625777 5.52E-05 4.258249784 0.849476409 S(ph)PGLCSDSLEK ddPTM_HeLa_Curcumin_4h_R1 1 SPGLCSDSLEK 11 0 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 0 S(1)PGLCSDSLEK 182.25 0.00012675 25052000 1427.8 1428.2 1350.8 1105.8 1313.6 1395.1 916.71 222.74 1532.7 1310 TRUE FALSE FALSE 1314.788123 1551.647244 1400.861836 1101.224493 1297.936178 1105.740534 942.4304154 290.6524006 1364.566645 1355.522402 0.969949387 1.144685799 1.033447941 0.812398593 0.95751732 0.81573018 0.695252556 0.21442095 1.006672145 1 10.40463324 -4.338547702 1.153852642 0.98967522 9.61E-28 0.891739696 0.082041893 0.323523255 0.382422464 0.012112385 0.371742616 4.59E-05 4.338547702 -0.98967522 down LTPVS(ph)PES(ph)SSTEEK ddPTM_HeLa_Curcumin_4h_R1 1 LTPVSPESSSTEEK 14 0 Q13501;E7EMC7;Q13501-2 Q13501 SQSTM1 Sequestosome-1 2 0 LT(0.001)PVS(0.936)PES(0.463)S(0.269)S(0.191)T(0.14)EEK 115.1 0.0052456 53366000 3081.5 2687.7 3122 3177.6 3504.1 4015.2 3682.6 4531 2931.2 2960.1 TRUE FALSE FALSE 2837.596023 2920.012812 3237.704066 3164.451933 3462.315896 3182.402259 3785.923845 5912.481042 2609.654694 3062.963255 0.92642183 0.953329364 1.057049595 1.033134148 1.13038114 1.038994593 1.23603306 1.930314062 0.852003265 1 11.58071234 -1.438843329 0.90466442 0.978546784 199.9999997 0.943889177 0.068634957 51.60804759 0.260799292 0.009693801 21005.42556 0.036404634 1.438843329 199.0214529 VSS(ph)QAEDTSSSFDNLFIDR ddPTM_HeLa_Curcumin_4h_R1 2 VSSQAEDTSSSFDNLFIDR 19 0 H8Y6P7;P0CAP2-3;P0CAP2;Q9BZD3 H8Y6P7 GCOM1;POLR2M;GCOM2 DNA-directed RNA polymerase II subunit GRINL1A;Putative GRINL1B complex locus protein 2 1 0 VS(0.029)S(0.971)QAEDTSSSFDNLFIDR;VS(0.021)S(0.965)QAEDT(0.01)S(0.003)S(0.001)SFDNLFIDR ; 199.09 1.11E-10 8733500 991.26 919.66 893.98 946.09 1110.21 1325.93 1341.03 3562.7 1182.39 1048.3 TRUE FALSE FALSE 912.800725 999.1513125 927.1116852 942.1753303 1096.971471 1050.917172 1378.655693 4648.950829 1052.684775 1084.728347 0.841501679 0.921107405 0.854694807 0.868581828 1.011286811 0.968829822 1.270968622 4.285820355 0.970459358 1 10.08311807 -4.253236107 3.466839952 0.925497441 4.733909246 0.996618964 0.058279637 0.01590218 0.321407201 0.010901681 0.160120911 5.58E-05 4.253236107 3.808411806 up LTPVS(ph)PESSSTEEK ddPTM_HeLa_Curcumin_4h_R1 2 LTPVSPESSSTEEK 14 0 Q13501;E7EMC7;Q13501-2 Q13501 SQSTM1 Sequestosome-1 1 0 LT(0.001)PVS(0.999)PESSSTEEK;LT(0.019)PVS(0.541)PES(0.337)S(0.1)S(0.002)T(0.001)EEK ; 244 8.45E-29 2488171800 6192.6 7861.7 6011.9 6507.9 5878.5 6743 4616.6 4079.56 6066.2 5498.6 TRUE FALSE FALSE 5702.449176 8541.230317 6234.706303 6480.972034 5808.402727 5344.425791 4746.129371 5323.399064 5400.753037 5689.675941 1.002244985 1.501180455 1.095792865 1.139075775 1.020867056 0.939319892 0.834165148 0.935624299 0.949219796 1 12.47413077 -5.215092828 2.864935405 1.059615649 0.886021309 0.242053371 0.150947551 0.369346148 5.981613459 0.023218967 0.065696184 6.09E-06 5.215092828 -0.17359434 LTPVSLS(ph)NSPIKGADCQEVPQDK ddPTM_HeLa_Curcumin_4h_R1 1 LTPVSLSNSPIKGADCQEVPQDK 23 1 P46100-5;P46100-3;P46100-4;P46100;P46100-2 P46100-5 ATRX Transcriptional regulator ATRX 1 0 LTPVS(0.021)LS(0.864)NS(0.114)PIKGADCQEVPQDK 78.057 0.00028538 51243000 2581.5 1894.3 2568.3 2316.3 2727.9 2546.3 1887.9 993.18 2056.7 2285.5 TRUE FALSE FALSE 2377.171551 2058.034851 2663.483457 2306.715764 2695.371574 2018.168677 1940.869393 1295.99601 1831.085156 2364.920955 1.005180129 0.870234097 1.126246292 0.975388103 1.139730091 0.8533768 0.820691021 0.548008172 0.774269073 1 11.20757625 -4.35741226 1.359735727 1.006421761 0.416024351 0.583135733 0.108649836 0.357001926 0.652011118 0.010666607 0.274268999 4.39E-05 4.35741226 -0.590397409 LTPVSLSNS(ph)PIK ddPTM_HeLa_Curcumin_4h_R1 2 LTPVSLSNSPIK 12 0 P46100-5;P46100-3;P46100-4;P46100;P46100-2 P46100-5 ATRX Transcriptional regulator ATRX 1 0 LTPVSLSNS(1)PIK;LTPVSLS(0.047)NS(0.952)PIK ; 192.46 4.54E-06 149396000 6237.4 5220.8 6099.5 5619.3 6722.9 7039.7 4406.9 2001.15 5274.5 4395.9 TRUE FALSE FALSE 5743.703208 5672.062689 6325.552836 5596.048826 6642.733808 5579.586866 4530.545753 2611.291423 4695.900546 4548.657198 1.262725011 1.246975193 1.390641801 1.230263918 1.460372483 1.226644837 0.996018288 0.574079626 1.032370729 1 12.151225 -4.341072178 2.576482787 1.190831688 0.501026435 0.677104128 0.136821841 0.227619584 2.145731817 0.023186556 0.311632084 4.56E-05 4.341072178 -0.689805253 S(ph)PGSTPTTPTSSQAPQK ddPTM_HeLa_Curcumin_4h_R1 3 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 0 S(0.426)PGS(0.196)T(0.375)PT(0.003)TPTSSQAPQK;S(0.996)PGS(0.003)T(0.001)PTTPTSSQAPQK;S(0.653)PGS(0.058)T(0.289)PTTPTSSQAPQK ;; 251.28 2.52E-40 89982800 6677.3 5371.4 6643.2 6823.2 7073.2 7270.1 4701.99 1934.37 6466.8 5972.3 TRUE FALSE FALSE 6148.784659 5835.679882 6889.402836 6794.967406 6988.85671 5762.199309 4833.915185 2524.150508 5757.408219 6179.83698 0.99497522 0.94430968 1.11481951 1.099538293 1.130912795 0.932419306 0.782207557 0.408449368 0.931644028 1 12.59335307 -4.336475433 1.704552372 1.017698901 0.255694952 0.887441534 0.067626307 0.186750477 0.589891269 0.009761325 0.219994114 4.61E-05 4.336475433 -0.76200395 down LTPVSPES(ph)SSTEEK ddPTM_HeLa_Curcumin_4h_R1 2 LTPVSPESSSTEEK 14 0 Q13501;E7EMC7;Q13501-2 Q13501 SQSTM1 Sequestosome-1 1 0 LT(0.217)PVS(0.228)PES(0.472)S(0.056)S(0.014)T(0.013)EEK;LTPVS(0.004)PES(0.468)S(0.468)S(0.047)T(0.014)EEK ; 169.58 0.00020473 29316000 3336.2 3083.7 2890 3457.2 3418.6 4572.6 2537.8 3415.3 3974.4 3127.2 TRUE FALSE FALSE 3072.13625 3350.241287 2997.105942 3442.895022 3377.835428 3624.191216 2609.003838 4456.609248 3538.418263 3235.869967 0.949400403 1.035344844 0.926213344 1.063978175 1.043872424 1.120005208 0.806275859 1.377252267 1.093498286 1 11.65993792 -4.243701357 24.72346672 0.987761516 1.377252643 0.610706177 0.088451591 1368.24006 1907035.901 0.010323743 0.425371825 5.71E-05 4.243701357 0.389491128 LTPVSPESS(ph)STEEK ddPTM_HeLa_Curcumin_4h_R1 1 LTPVSPESSSTEEK 14 0 Q13501;E7EMC7;Q13501-2 Q13501 SQSTM1 Sequestosome-1 1 0 LT(0.002)PVS(0.043)PES(0.344)S(0.445)S(0.122)T(0.044)EEK 71.286 0.014713 21944000 6877.3 6047.1 6675.2 6141.8 7234.1 7454.6 5471.1 4993.3 6979.8 5652.6 TRUE FALSE FALSE 6332.954448 6569.784379 6922.588784 6116.386859 7147.838082 5908.431929 5624.604341 6515.734184 6214.133403 5849.027429 1.082736322 1.123226803 1.183545276 1.045710066 1.222055832 1.010156304 0.9616307 1.113985917 1.062421655 1 12.51398104 -8.817404596 0.907578164 1.004848143 1.091375248 0.077945956 0.074814566 0.717701212 1.160472605 0.035421479 0.014725415 1.52E-09 8.817404596 0.086527106 LTPYEVDELRR ddPTM_HeLa_Curcumin_4h_R1 2 LTPYEVDELRR 11 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 0 ; ; 189.17 6.55E-05 34062000 5540.9 3782.6 4593.2 4587.6 4587.8 6476.2 5090.2 4707.3 5708.8 4757.6 FALSE FALSE TRUE 5102.331918 4109.551089 4763.428033 4568.617727 4533.093481 5132.963118 5233.017312 6142.5341 5082.558923 4922.926246 1.036442893 0.834778114 0.967600934 0.928028879 0.920812796 1.042665046 1.062989176 1.247740428 1.03242638 1 12.26530041 -4.193819733 1.580722091 0.988172187 1.373337004 0.646447175 0.06202176 0.697500385 1.425771897 0.009804776 0.43337904 6.40E-05 4.193819733 0.385164817 (ac)AHS(ph)PVAVQVPGMQNNIADPEELFTK ddPTM_HeLa_Curcumin_4h_R1 2 AHSPVAVQVPGMQNNIADPEELFTK 25 0 Q8NBY1;B4E0Y9;Q9P289-3;Q9P289 Q8NBY1 STK26 Serine/threonine-protein kinase 26 1 0 AHS(1)PVAVQVPGMQNNIADPEELFTK;AHS(1)PVAVQVPGMQNNIADPEELFTK ; 68.634 6.48E-09 48046000 3297.4 2944.4 2814.5 2832.5 3145.6 4250.7 3225 5693.2 2933.5 2830.5 TRUE FALSE FALSE 3036.407311 3198.900816 2918.807846 2820.779866 3108.090774 3369.056905 3315.48482 7429.030472 2611.702389 2928.859664 1.036719972 1.092200099 0.99656801 0.963098335 1.061194844 1.15029646 1.132005354 2.536492466 0.891713052 1 11.51612335 -4.253019623 3.927423474 1.030250703 2.690712859 0.978130001 0.067469477 0.021267316 0.652905753 0.007899483 0.101644733 5.58E-05 4.253019623 1.660462156 up LTQDQDVDVK ddPTM_HeLa_Curcumin_4h_R1 1 LTQDQDVDVK 10 0 P30153;B3KQV6;E9PH38 P30153 PPP2R1A Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 0 0 117.52 3.95E-07 0 2228.9 1817.5 1923.5 1751.4 2102.5 2055.6 1608.7 1701.9 2302.4 1987.7 FALSE FALSE TRUE 2052.480213 1974.596601 1994.786602 1744.153171 2077.429061 1629.245389 1653.835792 2220.801475 2049.83248 2056.772427 0.997913131 0.960046224 0.969862575 0.848004936 1.010043228 0.792136926 0.804092748 1.079750704 0.996625807 1 11.00616646 -6.636901982 1.415958858 0.999077125 0.899149005 0.170154704 0.083662378 0.431353396 1.744598167 0.013636633 0.021403877 2.31E-07 6.636901982 -0.09992812 LTQTSS(ph)TEQLNVLETETEVLNK ddPTM_HeLa_Curcumin_4h_R1 3 LTQTSSTEQLNVLETETEVLNK 22 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 LT(0.003)QT(0.114)S(0.34)S(0.398)T(0.145)EQLNVLETETEVLNK;LT(0.001)QT(0.052)S(0.176)S(0.595)T(0.176)EQLNVLETETEVLNK;LT(0.001)QT(0.061)S(0.186)S(0.567)T(0.186)EQLNVLETETEVLNK ;; 194.26 1.76E-13 66642000 9884.1 8084.4 9227.7 8903 10187.2 10428.3 9357.6 8751.5 8419.9 6790.1 TRUE FALSE FALSE 9101.763055 8783.179513 9569.68668 8866.161745 10065.72429 8265.353029 9620.149071 11419.79206 7496.258036 7026.05547 1.295430003 1.250086845 1.362028342 1.261897488 1.432628071 1.176385963 1.369210521 1.625348976 1.066922695 1 12.77849925 -12.8420803 0.125153299 1.54E-13 1.525843499 0.634271051 0.103532848 32.3038307 0.342272997 8.449903935 0.440751345 1.44E-13 12.8420803 1.525843499 LTQYHGGS(ph)LPNVSQLR ddPTM_HeLa_Curcumin_4h_R1 2 LTQYHGGSLPNVSQLR 16 0 Q6UUV7;Q6UUV7-3;H0YK33 Q6UUV7 CRTC3 CREB-regulated transcription coactivator 3 1 0 LT(0.025)QY(0.07)HGGS(0.905)LPNVSQLR;LT(0.081)QY(0.155)HGGS(0.762)LPNVS(0.003)QLR ; 75.611 0.0082704 46856000 5052.8 4158.9 4325.7 4559.5 5229.3 8087.9 4642 1158.52 5290.2 4537.3 TRUE FALSE FALSE 4652.865548 4518.376784 4486.014247 4540.633997 5166.944013 6410.378371 4772.242027 1511.747415 4709.878295 4694.970837 0.991031832 0.96238655 0.955493528 0.967127199 1.100527392 1.365371286 1.01645829 0.32199293 1.003175197 1 12.19690048 -4.261753396 9.105079378 1.02162506 0.319102959 0.770967831 0.117042177 0.029945428 52.71232999 0.016855448 0.130735255 5.47E-05 4.261753396 -0.702522101 LTRDETNYGIPQR ddPTM_HeLa_Curcumin_4h_R1 2 LTRDETNYGIPQR 13 1 P63244;D6RHH4;D6RAC2;D6REE5;D6R9L0;D6RAU2;E9PD14;D6RFX4;D6R9Z1;D6RGK8;D6RBD0;D6R909;D6RFZ9 P63244 GNB2L1 "Guanine nucleotide-binding protein subunit beta-2-like 1;Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed" 0 0 ; ; 128.08 0.00072658 6531100 2038.06 1847.82 1829.4 2041.3 1760.9 2211.59 1926.04 2162.1 2564.2 2137.03 FALSE FALSE TRUE 1876.7454 2007.537327 1897.199173 2032.853641 1739.902418 1752.881304 1980.079499 2821.314337 2282.913675 2211.291633 0.848710035 0.907857334 0.85795973 0.919305989 0.786826302 0.792695671 0.895440234 1.275867142 1.032389234 1 11.11067359 -4.260967701 24.12020575 0.900361352 1.27586732 0.69803966 0.075330202 11.00686776 562565.9934 0.011179271 0.088166322 5.48E-05 4.260967701 0.375505967 LTRPAAS(ph)PAVGEK ddPTM_HeLa_Curcumin_4h_R1 1 LTRPAASPAVGEK 13 1 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 0 LTRPAAS(1)PAVGEK 71.263 0.014819 100870000 5051.9 4370.7 4570.7 4309.9 4326 5677.5 4747.2 1778.9 5644.2 4936.5 TRUE FALSE FALSE 4652.036784 4748.483833 4740.094163 4292.066776 4274.415275 4499.922501 4880.393656 2321.278421 5025.045381 5108.043008 0.910727803 0.929609211 0.927966768 0.840256585 0.836800957 0.880948437 0.955433157 0.454435959 0.98375158 1 12.31855496 -4.259734865 24.99223188 0.932028799 0.454435799 0.871099199 0.053309354 43.56605273 638726.2351 0.008876601 0.076108836 5.50E-05 4.259734865 -0.477593 LTRT(ph)SGETTQTHTEPTGDSK ddPTM_HeLa_Curcumin_4h_R1 1 LTRTSGETTQTHTEPTGDSK 20 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 LT(0.118)RT(0.272)S(0.272)GET(0.143)T(0.143)QT(0.051)HTEPTGDSK 79.589 0.0022849 5314200 1628.7 1019.6 1143.8 1614.2 1210.8 3435.4 3541.4 658.62 1962.7 1523 TRUE FALSE FALSE 1499.786676 1107.729681 1186.190234 1607.520868 1196.362001 2722.859315 3640.762153 859.4302061 1747.39672 1575.924137 0.951687103 0.702907999 0.75269501 1.020049653 0.759149488 1.727785781 2.310239477 0.545349986 1.108807639 1 10.62198237 -5.258962091 24.9780159 0.929046669 1.606036549 0.309818776 0.423441485 167.5404408 1689263.924 0.053592673 0.129954546 5.51E-06 5.258962091 0.67698988 LTS(ph)DEEGEPSGK ddPTM_HeLa_Curcumin_4h_R1 4 LTSDEEGEPSGK 12 0 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 0 LT(0.038)S(0.962)DEEGEPSGK;LT(0.157)S(0.843)DEEGEPSGK;LT(0.078)S(0.922)DEEGEPSGK;LT(0.001)S(0.999)DEEGEPSGK ;;; 232.78 3.32E-19 396029000 25567.7 20871.4 23054.5 22765.7 24569.7 24816.6 21760.9 19346.1 24085 20081.9 TRUE FALSE FALSE 23543.98957 22675.43081 23908.92005 22671.50157 24276.72237 19669.35742 22371.45229 25244.63683 21442.93576 20779.74453 1.133025939 1.091227603 1.150587776 1.091038513 1.168287817 0.946563967 1.076599005 1.214867526 1.031915273 1 14.3428903 -9.35494164 1.007096972 0.998164824 1.10661112 0.226790151 0.067811297 0.613852949 1.084037921 0.048864277 0.011897312 4.42E-10 9.35494164 0.108446296 LTS(ph)DEEGEPSGKR ddPTM_HeLa_Curcumin_4h_R1 3 LTSDEEGEPSGKR 13 1 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 0 LT(0.089)S(0.911)DEEGEPSGKR;LT(0.001)S(0.983)DEEGEPS(0.016)GKR;LT(0.032)S(0.968)DEEGEPSGKR ;; 105.65 0.0017396 166303000 7270 6731.7 6747.5 7708.6 6906.8 8811.4 6809.09 6919.3 8799.8 7255.2 TRUE FALSE FALSE 6694.571829 7313.558152 6997.568286 7676.703856 6824.440921 6983.816315 7000.13474 9028.962717 7834.483956 7507.31766 0.891739518 0.974190581 0.932099666 1.022562812 0.909038518 0.930267857 0.932441527 1.202688247 1.043579653 1 12.87408181 -4.259201448 24.859141 0.948687892 1.202688343 0.689895091 0.04841371 73.4490862 815819.4054 0.006329365 0.056360364 5.51E-05 4.259201448 0.254000451 LTSPVTSIS(ph)PIQASEK ddPTM_HeLa_Curcumin_4h_R1 2 LTSPVTSISPIQASEK 16 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7 E9PMC9 C11orf30;EMSY Protein EMSY 1 0 LTSPVT(0.001)S(0.009)IS(0.99)PIQAS(0.001)EK;LTSPVT(0.001)S(0.01)IS(0.989)PIQASEK ; 135.23 0.00042944 34763000 6158.2 4461.8 5153.4 5727 4860.1 5694.6 4176.1 3174.4 6002.5 5450.8 TRUE FALSE FALSE 5670.771972 4847.458111 5344.389537 5703.303191 4802.146482 4513.475769 4293.270127 4142.259947 5344.040768 5640.214894 1.005417715 0.859445642 0.947550694 1.011185442 0.851411971 0.800231171 0.761189105 0.73441527 0.947488858 1 12.46153442 -4.946726092 0.499497775 1.002108074 0.625483374 0.736614562 0.050797639 0.763399069 0.194699324 0.011070225 0.148550715 1.13E-05 4.946726092 -0.376624701 IQSSLSSAS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 3 IQSSLSSASPSK 12 0 Q5W0B1 Q5W0B1 RNF219 RING finger protein 219 1 0 IQSSLS(0.004)S(0.044)AS(0.946)PS(0.006)K;IQSSLS(0.007)S(0.087)AS(0.897)PS(0.009)K;IQSSLSSAS(0.592)PS(0.407)K ;; 186.69 2.67E-05 128945000 9642.3 8350.4 9401.3 8630.8 9026 11258.4 6479.31 2636.31 10245.8 9112 TRUE FALSE FALSE 8879.10178 9072.171367 9749.720448 8595.088036 8918.370845 8923.280932 6661.102 3440.108783 9121.861374 9428.641322 0.941715935 0.962192861 1.034053594 0.911593489 0.945880805 0.946401568 0.706475278 0.364857318 0.967462974 1 13.20283418 -4.33323283 1.613768245 0.97098463 0.191468045 0.970365619 0.032732255 0.104554821 0.285248027 0.005045563 0.121573221 4.64E-05 4.33323283 -0.779516585 down LTTTGQVT(ph)SPVK ddPTM_HeLa_Curcumin_4h_R1 1 LTTTGQVTSPVK 12 0 K7ENR9;K7ERZ5;P49916-4;P49916-3;P49916-2;P49916 K7ENR9 LIG3 DNA ligase 3 1 0 LTTTGQVT(0.5)S(0.5)PVK 148.89 0.0018161 50812000 4891.2 3399.4 4815.6 4171.1 5313.2 5813.8 4621.2 2325.4 3988.3 3576.4 TRUE FALSE FALSE 4504.056359 3693.228989 4994.070372 4153.841093 5249.84356 4607.952345 4750.858435 3034.403755 3550.793468 3700.679634 1.217088969 0.997986682 1.349500866 1.122453577 1.41861606 1.245163808 1.283779982 0.819958509 0.959497665 1 11.85357453 -9.430080833 0.595485044 0.958870936 1.199676746 0.187456598 0.164802137 1.893428957 0.874434474 0.258325136 0.03518973 3.71E-10 9.430080833 0.24080581 LTTTGQVTS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 1 LTTTGQVTSPVK 12 0 K7ENR9;K7ERZ5;P49916-4;P49916-3;P49916-2;P49916 K7ENR9 LIG3 DNA ligase 3 1 0 LTTTGQVT(0.076)S(0.924)PVK 179.67 0.00010525 158910000 3683.1 2773.6 3308.6 2979 3426.8 3515.4 3212.1 1433.4 2912.2 2470.8 TRUE FALSE FALSE 3391.578749 3013.337625 3431.219627 2966.673687 3385.937648 2786.266413 3302.222881 1870.437061 2592.738946 2556.660116 1.326566143 1.178622691 1.342071089 1.160370778 1.324359709 1.089807126 1.291615909 0.731593945 1.014111704 1 11.32004467 -4.253005009 24.50958826 1.185566065 0.731593642 0.561659062 0.121888992 545.5083036 1585154.9 0.019086593 0.291576406 5.58E-05 4.253005009 -0.453972423 LTTTGQVTS(ph)PVKGASFVTSTNPR ddPTM_HeLa_Curcumin_4h_R1 2 LTTTGQVTSPVKGASFVTSTNPR 23 1 K7ENR9;K7ERZ5;P49916-4;P49916-3;P49916-2;P49916 K7ENR9 LIG3 DNA ligase 3 1 0 LTTTGQVT(0.132)S(0.867)PVKGASFVTSTNPR;LTTTGQVT(0.073)S(0.927)PVKGASFVTSTNPR ; 111.97 4.65E-06 507260000 3020.4 2198.7 2284.73 2485.4 2474.1 2762.9 2326.1 1319.91 3447.4 3026.8 TRUE FALSE FALSE 2781.332153 2388.745831 2369.404104 2475.116073 2444.597973 2189.843396 2391.364106 1722.344483 3069.228845 3131.981075 0.888042452 0.762694848 0.756519292 0.790271721 0.780527696 0.69918794 0.763530829 0.54992174 0.979964046 1 11.61285978 -3.425275461 0.097511671 1.207381023 8.03E-09 0.833044672 0.051334538 18.62109727 0.230273047 0.582186566 3.165017555 0.000375599 3.425275461 -1.207381015 LTVENS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 LTVENSPK 8 0 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 0 LT(0.262)VENS(0.738)PK;LT(0.226)VENS(0.774)PK ; 102.53 0.013571 154930000 13547.9 13081.2 14386 12665.8 16096.9 14355.6 12561.4 11036.5 12504 10435.1 TRUE FALSE FALSE 12475.56942 14211.88064 14919.15782 12613.39228 15904.95498 11378.08674 12913.83908 14401.47804 11132.34248 10797.71895 1.155389345 1.316192865 1.381695327 1.168153416 1.472992125 1.053749111 1.195978441 1.333751889 1.030990206 1 13.39843895 -8.001313775 0.984637853 1.030461073 1.268547579 0.433804459 0.114293793 0.307868405 0.633962721 0.031374237 0.024798521 9.97E-09 8.001313775 0.238086506 LTVENS(ph)PKQEAGISEGQGTAGEEEEK ddPTM_HeLa_Curcumin_4h_R1 1 LTVENSPKQEAGISEGQGTAGEEEEK 26 1 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 0 LT(0.023)VENS(0.735)PKQEAGIS(0.12)EGQGT(0.122)AGEEEEK 47.006 0.013424 130160000 1541.5 1394.9 1508.2 1663.8 2111.5 1570.6 1763.4 1121.9 1709.4 1390.8 TRUE FALSE FALSE 1419.488648 1515.46894 1564.095219 1656.915636 2086.321742 1244.839856 1812.876258 1463.962145 1521.883097 1439.130196 0.986351792 1.053045057 1.086833716 1.151331298 1.449710212 0.864994605 1.259702744 1.017254831 1.057502025 1 10.4909814 -6.75144741 1.980196828 0.994204631 1.152901631 0.136952445 0.143642875 0.361285137 2.9019857 0.02210312 0.031830752 1.77E-07 6.75144741 0.158697 LTVENS(ph)PKQEAGISEGQGTAGEEEEKKK ddPTM_HeLa_Curcumin_4h_R1 2 LTVENSPKQEAGISEGQGTAGEEEEKKK 28 3 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 0 LT(0.004)VENS(0.996)PKQEAGISEGQGTAGEEEEKKK;LT(0.025)VENS(0.753)PKQEAGIS(0.111)EGQGT(0.111)AGEEEEKKK ; 75.483 5.05E-05 119460000 8974.1 7533.7 7473.3 7879.8 7025.2 9158.7 7191.7 5851.5 9294.1 7886.8 TRUE FALSE FALSE 8263.790516 8184.879458 7750.267072 7847.195475 6941.429078 7259.08238 7393.479747 7635.595413 8274.560483 8160.865713 1.012611996 1.002942549 0.949686877 0.961564098 0.850575089 0.88949906 0.905967578 0.935635468 1.013931705 1 12.99450649 -6.32418564 1.544983223 1.005958859 0.897987399 0.778146047 0.025401966 0.122284489 0.572304492 0.004076186 0.007285221 4.74E-07 6.32418564 -0.107971461 LTVENSPKQEAGIS(ph)EGQGTAGEEEEK ddPTM_HeLa_Curcumin_4h_R1 2 LTVENSPKQEAGISEGQGTAGEEEEK 26 1 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 0 LT(0.002)VENS(0.116)PKQEAGIS(0.552)EGQGT(0.33)AGEEEEK;LTVENS(0.008)PKQEAGIS(0.989)EGQGT(0.002)AGEEEEK ; 52.926 0.0047542 83170700 1659.41 1675.84 1727.46 1624.76 2299.89 2686.25 1941.27 1509.92 2461.97 1984.44 TRUE FALSE FALSE 1528.065947 1820.692142 1791.481187 1618.037174 2272.465314 2129.09147 1995.736812 1970.287657 2191.898051 2053.399142 0.744164111 0.886672301 0.872446642 0.787979862 1.106684651 1.036861965 0.971918596 0.959524925 1.067448605 1 11.00379837 -5.763162035 24.99997782 0.870736863 1.016696495 0.274099509 0.096077537 42.74472379 620346.3296 0.015267661 0.028752678 1.73E-06 5.763162035 0.145959632 LTVENSPKQEAGIS(ph)EGQGTAGEEEEKKK ddPTM_HeLa_Curcumin_4h_R1 1 LTVENSPKQEAGISEGQGTAGEEEEKKK 28 3 F8VVL1;O43583 F8VVL1 DENR Density-regulated protein 1 0 LT(0.004)VENS(0.21)PKQEAGIS(0.393)EGQGT(0.393)AGEEEEKKK 59.005 0.0014938 14675000 1832.9 1440.8 1420.1 1374.5 1347.4 2003.2 1491.7 1660.5 2099.4 1520.5 TRUE FALSE FALSE 1687.824031 1565.336332 1472.730155 1368.812683 1331.333135 1587.713739 1533.553087 2166.778806 1869.101072 1573.337262 1.072766833 0.994914676 0.936054965 0.870005889 0.846184202 1.009137569 0.974713512 1.37718648 1.187985003 1 10.61961225 -4.259322591 24.83063128 0.997652209 1.377186624 0.612918414 0.092504188 85.03091077 997362.5572 0.011814847 0.104318803 5.50E-05 4.259322591 0.379534415 LTVS(ph)DGES(ph)GEEK ddPTM_HeLa_Curcumin_4h_R1 1 LTVSDGESGEEK 12 0 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6 P46100-5 ATRX Transcriptional regulator ATRX 2 0 LT(0.121)VS(0.879)DGES(1)GEEK 120.29 0.0084401 10524000 6671.2 6168.5 7200.1 6022.7 7285.2 7094.6 5855 3764.8 5892.5 5897.7 TRUE FALSE FALSE 6143.167481 6701.677654 7466.94204 5997.779663 7198.328748 5623.099987 6019.275542 4912.670189 5246.107492 6102.644636 1.00664021 1.098159577 1.223558389 0.982816471 1.179542506 0.921420191 0.986338858 0.805006761 0.859644925 1 12.57521887 -4.049228581 1.318552716 1.033874269 0.616047611 0.314755494 0.103349578 1.808264752 1.887579741 0.013089833 1.152750714 8.93E-05 4.049228581 -0.417826658 LTVS(ph)DGESGEEK ddPTM_HeLa_Curcumin_4h_R1 1 LTVSDGESGEEK 12 0 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6 P46100-5 ATRX Transcriptional regulator ATRX 1 0 LT(0.018)VS(0.589)DGES(0.393)GEEK 99.531 0.0095621 7740200 1390.7 1504.1 1228.2 1342.8 1614.6 1796.3 1452.8 1147.4 1245.6 1530.2 TRUE FALSE FALSE 1280.624628 1634.107702 1273.718172 1337.243849 1595.34695 1423.727132 1493.561658 1497.236978 1108.960796 1583.374336 0.808794609 1.032041296 0.804432751 0.844553192 1.007561455 0.899172798 0.943277672 0.945598867 0.700378155 1 10.62878666 -5.763361569 24.99999043 0.904955395 0.944948765 0.070239718 0.0980078 147.5833063 1919511.906 0.013014733 0.024477156 1.72E-06 5.763361569 0.03999337 LTVSSLQESGLK ddPTM_HeLa_Curcumin_4h_R1 1 LTVSSLQESGLK 12 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 156.01 2.14E-05 1193400 354.1 277.54 363.62 367.21 498.87 523.02 392.89 269.72 326.63 206.19 FALSE FALSE TRUE 326.0726114 301.5293209 377.0960771 365.6905823 492.9213011 414.5397563 403.913436 351.9563864 290.7995062 213.3550872 1.528309522 1.413274579 1.767457632 1.713999826 2.310333012 1.942956983 1.893151185 1.649627347 1.3629837 1 7.7371127 -7.822926947 0.396807485 0.972734863 1.971597859 0.611432609 0.213576927 0.398295743 0.168406947 0.155129314 0.106172102 1.50E-08 7.822926947 0.998862996 LTWHS(ph)CPEDEAQ ddPTM_HeLa_Curcumin_4h_R1 4 LTWHSCPEDEAQ 12 0 Q13185 Q13185 CBX3 Chromobox protein homolog 3 1 0 LTWHS(1)CPEDEAQ;LTWHS(1)CPEDEAQ;LTWHS(1)CPEDEAQ;LTWHS(1)CPEDEAQ ;;; 112.02 0.004978 517449000 19411 16092.6 17436.2 16401.9 15867.2 20788.9 16757.9 15030.1 19446.6 16086.9 TRUE FALSE FALSE 17874.59887 17483.57264 18082.40091 16334.03328 15677.994 16477.0478 17228.08157 19612.7083 17313.35663 16645.91858 1.073812706 1.050321889 1.086296369 0.981263558 0.941852138 0.989855124 1.034973317 1.178229258 1.040096198 1 14.02288086 -11.33344657 0.003436295 2.10E-05 2.038574213 0.031580914 0.061980812 268695.078 115.2205908 35264.10584 33118.89327 4.64E-12 11.33344657 2.038553243 LTWHSCPEDEAQ ddPTM_HeLa_Curcumin_4h_R1 1 LTWHSCPEDEAQ 12 0 Q13185 Q13185 CBX3 Chromobox protein homolog 3 0 0 100.48 0.008984 3032800 1320.6 1339.7 1157.5 1268.9 1477.8 1768.5 1206 1127 1582.5 1134.7 FALSE FALSE TRUE 1216.073117 1455.497698 1200.397968 1263.649628 1460.1782 1401.693165 1239.837114 1470.617112 1408.903709 1174.130741 1.035722066 1.239638524 1.022371638 1.076242691 1.243624879 1.193813531 1.055961718 1.252515637 1.199954707 1 10.19737735 -7.173255252 0.502086775 0.996878844 1.176315522 0 0.101589933 0.601751217 0.357958719 0.029766387 0.037936791 6.71E-08 7.173255252 0.179436678 LVALTLAR ddPTM_HeLa_Curcumin_4h_R1 1 LVALTLAR 8 0 Q5SZD4 Q5SZD4 GLYATL3 Glycine N-acyltransferase-like protein 3 0 0 96.19 0.013795 43465000 1926.5 1630.3 1309.1 1548.9 1651.9 2303.8 1532.3 1547.3 1746.2 1628.9 FALSE FALSE TRUE 1774.015492 1771.215868 1357.616398 1542.491062 1632.202171 1825.965911 1575.292214 2019.064647 1554.646229 1685.504154 1.052513272 1.050852271 0.805466065 0.915151149 0.968376238 1.083335159 0.934611885 1.197899538 0.92236274 1 10.71896447 -4.24868171 23.73174966 1.000696636 1.197899796 0.356937791 0.083072967 912.2198648 1696844.196 0.011502623 0.260588097 5.64E-05 4.24868171 0.19720316 LVAMGFS(ph)PY(ph)NVSK ddPTM_HeLa_Curcumin_4h_R1 1 LVAMGFSPYNVSK 13 0 F6TD35 F6TD35 DHRS4L2 2 0 LVAMGFS(0.986)PY(0.981)NVS(0.033)K 84.169 0.012032 8957800 646.88 539.18 437.86 592.57 673.43 706.68 465.3 521.02 548.21 364.34 TRUE FALSE FALSE 595.6787654 585.7843167 454.0874768 590.1181024 665.3997871 560.1066021 478.3550657 679.8765995 488.0727346 377.0007879 1.580046474 1.553801306 1.204473549 1.565296735 1.764982484 1.4856908 1.268843676 1.803382437 1.294619932 1 8.558423728 -9.330479938 0.714191906 0.940287717 1.526064428 0.331357639 0.19795336 0.545371574 0.417076904 0.197748281 0.035762349 4.67E-10 9.330479938 0.585776711 LVAMGFS(ph)PYNVS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 LVAMGFSPYNVSK 13 0 F6TD35 F6TD35 DHRS4L2 2 0 LVAMGFS(0.618)PY(0.384)NVS(0.998)K 89.886 0.015135 8004000 1605.8 1461.9 1456.4 2227.4 1778.8 1241.9 852.88 1060 1992.3 1577.9 TRUE FALSE FALSE 1478.699236 1588.260122 1510.375465 2218.183609 1757.588972 984.3159409 876.8095174 1383.18912 1773.749674 1632.731908 0.905659544 0.972762347 0.925060298 1.35857185 1.076471259 0.602864399 0.537019895 0.847162424 1.086369211 1 10.67307221 -5.257553661 24.99239963 0.991478147 0.649815987 0.570372086 0.1473289 204.5925073 1315903.168 0.021323073 0.052187353 5.53E-06 5.257553661 -0.34166216 LVARPEPATGYTLEFR ddPTM_HeLa_Curcumin_4h_R1 4 LVARPEPATGYTLEFR 16 1 Q16658 Q16658 FSCN1 Fascin 0 0 ;;; ;;; 114.31 0.00045169 79648700 4230.63 3412.98 4073.45 3351.62 3798.21 6441.53 4389.37 4339.02 4930.73 3804.25 FALSE FALSE TRUE 3895.771171 3707.982783 4224.41564 3337.751885 3752.918826 5105.484067 4512.523909 5661.967224 4389.841255 3936.447404 0.989666766 0.941961724 1.073154346 0.847909686 0.953377104 1.29697759 1.146344266 1.438344437 1.115178435 1 11.94267849 -5.2600325 24.99843545 0.983196846 1.279134331 0.683769648 0.094882725 45.55006369 809356.7224 0.011016188 0.02650908 5.49E-06 5.2600325 0.295937485 LVDVS(ph)PDR ddPTM_HeLa_Curcumin_4h_R1 1 LVDVSPDR 8 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 0 LVDVS(1)PDR 99.53 0.015328 8305500 2891.1 2479.4 2675.8 2844.5 3649.6 3208.1 2448.9 1582.3 2790 2637.5 TRUE FALSE FALSE 2662.266384 2693.708288 2774.967502 2832.730213 3606.080904 2542.703897 2517.609543 2064.735986 2483.94398 2729.152929 0.97549183 0.987012585 1.016787104 1.037952173 1.321318738 0.931682454 0.92248753 0.756548292 0.910151994 1 11.41423752 -4.411882808 2.061720776 1.014402134 0.731147663 0.374698522 0.106614335 0.430091753 2.500096319 0.014690645 0.200972294 3.87E-05 4.411882808 -0.283254471 LVDVS(ph)PDRGS(ph)PPSRVPQALNFSPEESDSTFSK ddPTM_HeLa_Curcumin_4h_R1 2 LVDVSPDRGSPPSRVPQALNFSPEESDSTFSK 32 2 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 2 0 LVDVS(0.948)PDRGS(0.805)PPS(0.241)RVPQALNFS(0.006)PEESDSTFSK;LVDVS(0.906)PDRGS(0.764)PPS(0.278)RVPQALNFS(0.04)PEES(0.006)DS(0.003)T(0.003)FSK ; 71.903 1.65E-05 33763000 4350.3 3146.2 3578.9 3772.3 3236.7 5073.3 3410.2 1984.81 4972.4 4112.7 TRUE FALSE FALSE 4005.969165 3418.143509 3711.537182 3756.691222 3198.104466 4021.040392 3505.881034 2589.969432 4426.94016 4255.616019 0.941337082 0.803207689 0.872150393 0.882760852 0.751502121 0.944878573 0.823824569 0.608600358 1.040258365 1 12.05515227 -1.36889238 0.13782006 1.052817612 5.46E-14 0.597677822 0.076540794 36.32039243 0.365239563 0.217882211 7.412485704 0.042766885 1.36889238 -1.052817612 ATGEPGTFVCTSHLPAAAS(ph)ASPK ddPTM_HeLa_Curcumin_4h_R1 2 ATGEPGTFVCTSHLPAAASASPK 23 0 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 0 ATGEPGTFVCTSHLPAAAS(0.588)AS(0.412)PK;ATGEPGTFVCTSHLPAAAS(0.619)AS(0.381)PK ; 131.56 2.35E-06 100584000 5756.3 4095 4811.7 5250.5 4763.1 5247.7 3304.9 1018.96 5806.7 4830.1 TRUE FALSE FALSE 5300.682781 4448.953553 4990.025835 5228.774822 4706.303143 4159.267866 3397.626599 1329.636213 5169.719538 4997.945615 1.060572321 0.890156455 0.998415393 1.046184818 0.94164753 0.832195503 0.679804636 0.266036551 1.034368906 1 12.28711949 -4.33317214 1.079509872 1.015934264 9.20E-17 0.951054173 0.051193201 0.233774159 0.233226993 0.00810952 0.262415752 4.64E-05 4.33317214 -1.015934264 down LVEDEERR ddPTM_HeLa_Curcumin_4h_R1 2 LVEDEERR 8 1 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 0 ; ; 132.76 0.0068912 43096000 6656.4 6256.5 6648 7480.2 6162.7 7189 5858.9 4875.2 6668 7353.4 FALSE FALSE TRUE 6129.538916 6797.283982 6894.380728 7449.248914 6089.213827 5697.920363 6023.284966 6361.626037 5936.537083 7608.930103 0.805571721 0.893329797 0.90609069 0.979013976 0.800272015 0.748846459 0.791607346 0.83607366 0.780206547 1 12.89347789 -13.52287875 0.260891441 2.083619351 0.82401236 0 0.093583281 33.56351648 0.447913375 18.83884411 0.038272272 3.00E-14 13.52287875 -1.259606991 LVEDMENK ddPTM_HeLa_Curcumin_4h_R1 2 LVEDMENK 8 0 B1AK87;P47756-2;P47756;B1AK88 B1AK87 CAPZB F-actin-capping protein subunit beta 0 0 ; ; 123.98 0.0022942 12154000 4944.4 3918.7 4207.3 5013.6 4733.8 4937.4 4054.9 3950.8 5221.5 4085.7 FALSE FALSE TRUE 4553.045523 4257.414967 4363.226239 4992.855052 4677.352527 3913.327584 4168.669581 5155.380733 4648.714514 4227.677771 1.076961341 1.007033931 1.032062157 1.180992337 1.106364482 0.925644715 0.986042411 1.219435589 1.099590547 1 12.0456497 -9.496923375 0.732111201 0.989922579 1.063440637 0 0.088889491 2.407917368 1.770325188 0.115944388 0.016679239 3.18E-10 9.496923375 0.073518057 LVEEHLDSEIQKLDQMDEDELER ddPTM_HeLa_Curcumin_4h_R1 1 LVEEHLDSEIQKLDQMDEDELER 23 1 F8WBV5;G3XAJ4;F8WCJ3;B8ZZX4;O14530-2;O14530 F8WBV5 TXNDC9 Thioredoxin domain-containing protein 9 0 0 70.02 0.00048712 2082100 560.03 403.34 381.12 380.7 551.67 795.77 408.28 602.83 705.07 452.48 FALSE FALSE TRUE 515.7030346 438.2029124 395.2446425 379.1247643 545.0916956 630.7183318 419.735238 786.6300919 627.725585 468.2036463 1.101450274 0.93592375 0.8441725 0.809743297 1.164219245 1.347102563 0.896480071 1.680102447 1.340710586 1 8.87099236 -2.650279384 1.84042129 1.029729832 199.9999999 0.491645833 0.186776965 249.4665446 3.374043732 0.022867026 207641.1359 0.002237281 2.650279384 198.9702701 LVEPHS(ph)PSPSSK ddPTM_HeLa_Curcumin_4h_R1 2 LVEPHSPSPSSK 12 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 0 LVEPHS(0.993)PS(0.007)PSSK;LVEPHS(0.954)PS(0.042)PS(0.002)S(0.002)K ; 147.52 0.00071655 73091000 16233.5 13455 13187.3 13788.4 15567.3 18543.6 13035.9 8005.4 17604.1 13311.5 TRUE FALSE FALSE 14948.60135 14617.99025 13676.03294 13731.34725 15381.67011 14697.44833 13401.65227 10446.20961 15672.97427 13774.07363 1.085270904 1.061268484 0.992882229 0.996898058 1.116711768 1.067037154 0.972962148 0.758396527 1.137860497 1 13.74966767 -4.297169027 2.748991011 1.042782359 0.716680438 0.769283351 0.048919801 0.134367147 1.432342895 0.006321965 0.094829266 5.04E-05 4.297169027 -0.32610192 LVEVDSGR ddPTM_HeLa_Curcumin_4h_R1 1 LVEVDSGR 8 0 P20700;E9PBF6;A0A0D9SFE5 P20700 LMNB1 Lamin-B1 0 0 95.815 0.017245 2760500 3882.4 2815.1 3300.4 3609.8 3185.6 3535.6 2856.5 2563.1 4025.1 3676.6 FALSE FALSE TRUE 3575.103943 3058.4247 3422.715727 3594.863604 3147.613801 2802.276706 2936.645702 3344.577391 3583.5566 3804.361576 0.939738211 0.803925873 0.899682025 0.944932161 0.82736978 0.736595786 0.771915509 0.87914288 0.941960045 1 11.89343865 -6.968984136 0.360319402 1.00749452 0.780687613 0.467083263 0.059716821 0.654048899 0.226205214 0.036901519 0.056115613 1.07E-07 6.968984136 -0.226806907 LVEWIIVQCGPDVGRPDR ddPTM_HeLa_Curcumin_4h_R1 2 LVEWIIVQCGPDVGRPDR 18 1 Q01995;E9PJ32 Q01995 TAGLN Transgelin 0 0 ; ; 169.15 1.01E-05 71541000 2924.3 2180.97 2630.63 2479.98 2360.3 3735.9 2419.62 2482.14 2800.9 2627.68 FALSE FALSE TRUE 2692.838569 2369.483329 2728.123462 2469.7185 2332.154964 2961.032228 2487.508025 3238.93306 2493.648278 2718.991684 0.990381318 0.871456629 1.003358516 0.908321461 0.857727877 1.089018493 0.914864153 1.191225806 0.917122436 1 11.40885602 -4.251377099 24.57324224 0.974849802 1.191225957 0.481144198 0.071053109 742.412144 1813009.845 0.009080522 0.16411786 5.61E-05 4.251377099 0.216376155 LVEYDIDEVVYDEDSPYQNIK ddPTM_HeLa_Curcumin_4h_R1 1 LVEYDIDEVVYDEDSPYQNIK 21 0 P52788;P52788-2;H7C2R7 P52788 SMS Spermine synthase 0 0 107.65 4.27E-05 3160200 867.89 672.7 627.92 696.1 812.8 933.16 499.23 586.74 809.01 799.89 FALSE FALSE TRUE 799.1955907 730.8451905 651.1912676 693.2197226 803.1078909 739.6120971 513.2370502 765.634325 720.263627 827.686118 0.965578102 0.882998004 0.786761133 0.837539386 0.970304894 0.893590071 0.620086575 0.925029801 0.870213492 1 9.69293995 -7.206927126 2.61147475 0.985535331 0.83701053 0.161833229 0.096027683 0.224290195 2.951709384 0.015397219 0.01862643 6.21E-08 7.206927126 -0.1485248 LVFDFVEYEKDT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 LVFDFVEYEKDTPK 14 1 Q9UBU7 Q9UBU7 DBF4 Protein DBF4 homolog A 1 0 LVFDFVEY(0.003)EKDT(0.997)PK 89.866 0.0082676 21336000 1753.4 1244.3 1510.7 1824 1483.3 1747.2 1897.3 503.13 1781 1651.2 TRUE FALSE FALSE 1614.61654 1351.851748 1566.687871 1816.452771 1465.612616 1384.811025 1950.533132 656.5320209 1585.628756 1708.579077 0.94500545 0.791214036 0.916953679 1.063136495 0.857796186 0.810504497 1.141611271 0.384256152 0.928039432 1 10.73858131 -4.249377246 24.77643316 0.953222524 0.38425576 0.719397739 0.10368128 629.3725661 1292747.564 0.013641997 0.302491603 5.63E-05 4.249377246 -0.568966764 LVFLGLDNAGK ddPTM_HeLa_Curcumin_4h_R1 2 LVFLGLDNAGK 11 0 D6RD69;Q9Y6B6;X1WI22;D6RAA2;Q5SQT8;D6RDB2;Q9NR31 D6RD69;Q9NR31 SAR1B;SAR1A GTP-binding protein SAR1b;GTP-binding protein SAR1a 0 0 ; ; 137.95 0.0002348 1294960 774.76 750.31 779.52 729.02 1019.87 1223.61 954.4 1003.11 636.75 855.58 FALSE FALSE TRUE 713.4369285 815.1634531 808.4096969 726.0035084 1007.708716 969.8194931 981.1778954 1308.953621 566.9001181 885.3113413 0.805859922 0.920764724 0.913136045 0.820054454 1.138253481 1.095455856 1.108285695 1.478523498 0.640339835 1 9.790041093 -1.936727439 0.567482241 0.904504134 9.643444628 0.711957376 0.117774746 15.1726579 0.36805397 0.017839034 149.250449 0.01156838 1.936727439 8.738940494 LVGATATSS(ph)PPPK ddPTM_HeLa_Curcumin_4h_R1 3 LVGATATSSPPPK 13 0 H9KVD1;Q96QD9-4;Q96QD9 H9KVD1 FYTTD1 UAP56-interacting factor 1 0 LVGATAT(0.022)S(0.191)S(0.787)PPPK;LVGATAT(0.002)S(0.016)S(0.982)PPPK;LVGATAT(0.003)S(0.022)S(0.975)PPPK ;; 152.4 0.00045942 111979300 14156.4 12723.1 12588.8 14365.8 13318.1 18093.5 15630.5 8067.3 14866.7 13328.8 TRUE FALSE FALSE 13035.906 13822.82807 13055.352 14306.35813 13159.29036 14340.70414 16069.04976 10526.98263 13235.8602 13791.97481 0.945180526 1.002237045 0.946590476 1.037295842 0.954126624 1.039786132 1.165101444 0.763268696 0.959678392 1 13.75154142 -6.271403021 24.46978249 0.974135663 1.002097247 0.005902323 0.095830487 2064.87919 5071146.063 0.013479247 0.020718843 5.35E-07 6.271403021 0.027961584 LVGIISSR ddPTM_HeLa_Curcumin_4h_R1 1 LVGIISSR 8 0 P12268;H0Y4R1;E7ETK5 P12268 IMPDH2 Inosine-5-monophosphate dehydrogenase 2 0 0 92.467 0.020307 3106600 1239.7 835.13 1198.9 859.35 799.4 1418.8 1199.1 912.33 925.02 921.94 FALSE FALSE TRUE 1141.576437 907.3149159 1243.332289 855.7942374 789.8676771 1124.524887 1232.743519 1190.495217 823.5476203 953.9773464 1.196649419 0.951086438 1.30331427 0.897080251 0.827973201 1.178775252 1.292214667 1.247928184 0.863277963 1 9.897811197 -5.005494299 23.61009786 1.067338548 1.261427463 0.299270343 0.148158475 124.4504014 534809.9743 0.019717243 0.056593884 9.87E-06 5.005494299 0.194088915 LVHDS(ph)LEDLQMTR ddPTM_HeLa_Curcumin_4h_R1 2 LVHDSLEDLQMTR 13 0 A0A087WYY3;A0A2R8Y635;A0A2R8YDN7;Q9H7F0-2;Q9H7F0 A0A087WYY3 ATP13A3 Probable cation-transporting ATPase 13A3 1 0 LVHDS(1)LEDLQMTR;LVHDS(1)LEDLQMTR ; 91.932 0.0052823 9221300 5442.9 4644 5183 6437.6 5420.3 6005.4 3589.6 2534.63 7134.1 6594.4 TRUE FALSE FALSE 5012.088722 5045.406667 5375.086539 6410.962917 5355.666463 4759.812345 3690.314515 3307.427019 6351.507079 6823.554909 0.734527499 0.739410283 0.787725256 0.939534158 0.784879221 0.697556099 0.540819934 0.484707321 0.930820835 1 12.73630783 -3.612303511 0.10515649 1.130177771 1.63E-30 0.649438692 0.093436136 34.29698026 0.483789314 1.035968145 5.825772573 0.000244172 3.612303511 -1.130177771 LVIEEAER ddPTM_HeLa_Curcumin_4h_R1 1 LVIEEAER 8 0 P50991-2;P50991 P50991-2 CCT4 T-complex protein 1 subunit delta 0 0 93.374 0.019477 3729300 2564.4 2655.2 2790.1 2709.2 3018.8 3587.5 3459.5 2934.2 3638.8 3191.5 FALSE FALSE TRUE 2361.425034 2884.703657 2893.50356 2697.990048 2982.802782 2843.412061 3556.564259 3828.824073 3239.632744 3302.404387 0.715062348 0.873516177 0.876180873 0.81697749 0.903221542 0.861012683 1.076962068 1.159404974 0.980992139 1 11.68930108 -4.672986126 3.237404456 0.862400145 1.147132759 0.608885616 0.077135318 0.151440864 3.030137085 0.014561416 0.067602617 2.12E-05 4.672986126 0.284732615 LVIGDHK ddPTM_HeLa_Curcumin_4h_R1 1 LVIGDHK 7 0 E9PM92;O00193;E9PRZ9 E9PM92 C11orf58;SMAP Small acidic protein 0 0 89.142 0.0096591 3247800 3015.7 2409.3 2535.3 2688.2 2744.9 3454.8 2573.6 2670.4 2874.4 2775.1 FALSE FALSE TRUE 2777.004163 2617.549156 2629.260448 2677.076941 2712.16886 2738.235536 2645.80829 3484.592667 2559.085511 2871.534518 0.967080195 0.91155065 0.915629059 0.932280954 0.94450157 0.953579182 0.921391776 1.21349496 0.891190928 1 11.48760619 -4.2555526 24.99472605 0.963363074 1.213495069 0.809601461 0.038349885 223.8441757 950393.947 0.005463675 0.065524622 5.55E-05 4.2555526 0.250131995 LVIIEGDLERTEER ddPTM_HeLa_Curcumin_4h_R1 2 LVIIEGDLERTEER 14 1 A0A087WWU8;P06753-2;P06753-5;P06753-3;P06753-6;P06753-4;P06753-7;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 0 ; ; 158.34 0.00028841 17585500 7375.3 6033 5734.9 6027.5 5736.2 7925.7 5831.9 6359.6 8101.8 6764.2 FALSE FALSE TRUE 6791.537223 6554.465637 5947.440439 6002.559802 5667.799561 6281.820479 5995.527418 8298.612764 7213.05281 6999.255447 0.970322811 0.936451839 0.849724729 0.857599762 0.809771783 0.897498388 0.856595028 1.18564222 1.030545729 1 12.77298575 -7.196344078 2.581622409 0.987163599 0.899536373 0.133829848 0.099251471 0.411888854 5.289671061 0.01655867 0.020109775 6.36E-08 7.196344078 -0.087627226 LVIIESDLERAEER ddPTM_HeLa_Curcumin_4h_R1 2 LVIIESDLERAEER 14 1 P09493-3;H0YKX5;P09493-9;H7BYY1;Q6ZN40;P09493-2;P09493-8;F5H7S3;B7Z596;P09493-7;A0A494BZZ2;P09493-5;H0YL42;A0A494C0V8;P09493-4;P09493-10;A0A0S2Z4G6;P09493;H0YKJ4;H0YK48;P09493-6 P09493-3;P09493-4 TPM1 Tropomyosin alpha-1 chain 0 0 ; ; 195.77 2.78E-06 18526200 4842.6 4256.2 3645.3 3926.4 3737.3 5880.7 4346 4515.2 5306.7 4429.5 FALSE FALSE TRUE 4459.3031 4624.086963 3780.398025 3910.153597 3692.735138 4660.976531 4467.937063 5891.863695 4724.568287 4583.424795 0.972919443 1.008871569 0.824797655 0.853107397 0.805671589 1.016920041 0.974803179 1.285471881 1.030794329 1 12.16221029 -4.240552149 3.615989403 0.956708124 1.330520184 0.615268186 0.080652871 0.18229052 4.101124372 0.0118672 0.187574758 5.75E-05 4.240552149 0.373812059 LVILANNCPALR ddPTM_HeLa_Curcumin_4h_R1 2 LVILANNCPALR 12 0 P62888;E5RI99;E5RJH3 P62888 RPL30 60S ribosomal protein L30 0 0 ; ; 199.7 1.07E-14 4909400 1603.75 1916.13 1771.24 1405.2 1552.15 3254.2 2298.04 1946.57 1560.11 1430.61 FALSE FALSE TRUE 1476.811495 2081.751739 1836.883713 1399.385655 1533.641625 2579.242238 2362.516818 2540.070232 1388.969836 1480.323591 0.997627481 1.40628154 1.240866337 0.94532416 1.036017824 1.74235029 1.595946205 1.715888504 0.938287983 1 10.53169686 -5.264539097 24.87102711 1.046831458 1.675850142 0.786270728 0.143555032 82.46011143 661633.7023 0.021833557 0.050851283 5.44E-06 5.264539097 0.629018684 LVILEGELERAEER ddPTM_HeLa_Curcumin_4h_R1 1 LVILEGELERAEER 14 1 P67936;A0A2R8Y5V9;A0A2R8YGX3;A0A2R8YH90;A0A2R8YE05;P67936-2;K7ENT6;A0A2R8YEU4;A0A2R8YHD2;A0A5F9UN72 P67936 TPM4 Tropomyosin alpha-4 chain 0 0 122.46 0.0013665 9426600 954.65 824.69 626.27 1010.1 941.18 1236.6 916.41 1133.8 1198 1036.3 FALSE FALSE TRUE 879.0884452 895.9725289 649.4801171 1005.920474 929.9570432 980.1152206 942.1219982 1479.490401 1066.582397 1072.311348 0.81980709 0.835552595 0.605682406 0.938086197 0.867245362 0.914021121 0.878589973 1.379720921 0.994657381 1 10.06650814 -4.261062579 24.7163684 0.8839108 1.379721074 0.669367931 0.106652709 13.15522335 862537.1181 0.015832205 0.124418018 5.48E-05 4.261062579 0.495810274 LVINGNPITIFQER ddPTM_HeLa_Curcumin_4h_R1 4 LVINGNPITIFQER 14 0 P04406;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 ;;; ;;; 237.76 4.11E-38 23053260 1624.2 1367.14 1833.35 1662.681 1474.65 2337.48 1693.03 1917.27 1297.93 830 FALSE FALSE TRUE 1495.642856 1485.30949 1901.295564 1655.801267 1457.065762 1852.660299 1740.531865 2501.836797 1155.550326 858.8424382 1.741463614 1.729431877 2.213788559 1.927945328 1.696546068 2.157159703 2.026602072 2.913033504 1.345474181 1 9.746249671 -7.145841449 0.106540116 6.49E-17 3.498545792 0.707454138 0.265777344 3.1970011 0.28428869 4.176101521 4.64322686 7.15E-08 7.145841449 3.498545792 up LVINGNPITIFQERDPS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 LVINGNPITIFQERDPSK 18 1 P04406;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 0 LVINGNPIT(0.013)IFQERDPS(0.987)K 60.735 0.011991 36206000 1044.7 1033.6 1169.8 1207 883.29 1451.7 1016.5 1100.1 962.21 1042.1 TRUE FALSE FALSE 962.0108926 1122.939778 1213.153817 1202.005754 872.7573436 1150.601056 1045.020254 1435.515426 856.6579703 1078.312897 0.892144474 1.041385836 1.125048045 1.114709614 0.809372999 1.067038203 0.969125248 1.331260555 0.794442849 1 10.07456015 -7.135060283 6.621264571 0.949228406 1.057135798 0.221027418 0.134960579 0.366973355 18.38000123 0.020545524 0.025222811 7.33E-08 7.135060283 0.107907392 LVINGNPITIFQERDPS(ph)KIK ddPTM_HeLa_Curcumin_4h_R1 1 LVINGNPITIFQERDPSKIK 20 2 P04406;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 0 LVINGNPITIFQERDPS(1)KIK 130.45 6.05E-05 378270000 2005.8 1497.3 1548.2 1757.1 1616.2 2275.6 1709.2 2121 1995.7 1480.1 TRUE FALSE FALSE 1847.038813 1626.71994 1605.577654 1749.829586 1596.927871 1803.614909 1757.155552 2767.683136 1776.776703 1531.533365 1.206006252 1.06215116 1.048346507 1.142534421 1.042698714 1.177653031 1.14731784 1.80713212 1.160129282 1 10.58076108 -4.246143494 3.63406884 1.098035645 1.89868767 0.915403089 0.06367757 0.075728952 1.758613411 0.011193911 0.166624776 5.67E-05 4.246143494 0.800652025 LVINGNPITIFQERDPSK ddPTM_HeLa_Curcumin_4h_R1 3 LVINGNPITIFQERDPSK 18 1 P04406;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 ;; ;; 172.42 5.88E-06 71922010 2398.92 1784.45 1930.46 2105.31 1868.33 3151.84 2459.28 2258.45 2500.27 1682.66 FALSE FALSE TRUE 2209.042951 1938.689907 2002.004546 2096.598785 1846.051385 2498.112855 2528.280778 2947.041008 2225.996636 1741.13231 1.268739279 1.113465011 1.149829071 1.204158221 1.060259105 1.434763367 1.452089978 1.692600265 1.27847644 1 10.76581012 -1 0.439689305 1.1130779 13.9193589 0.738286437 0.102179043 27.72934428 0.305566886 0.02462349 319.5318196 0.1 1 12.806281 LVKPGNQNTQVTEAWNK ddPTM_HeLa_Curcumin_4h_R1 2 LVKPGNQNTQVTEAWNK 17 1 Q9UQ80;Q9UQ80-2;F8VR77;H0YIN7;F8W0A3 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 0 ; ; 171.46 5.85E-05 6446900 3023.8 2161.98 1996.46 2473.3 2678.26 2985.1 2342.7 2274.64 2901.5 2399.6 FALSE FALSE TRUE 2784.463039 2348.851918 2070.450564 2463.06614 2646.323499 2365.956611 2408.429857 2968.167265 2583.212709 2482.985921 1.121417168 0.94597875 0.833855136 0.991977489 1.065782724 0.952867509 0.969973223 1.195402374 1.040365427 1 11.27786037 -10.14554336 3.2994996 0.998993954 1.031911373 0 0.09785002 1.473871286 29.53666216 0.096475305 0.015120808 7.15E-11 10.14554336 0.032917419 LVLAES(ph)PQPK ddPTM_HeLa_Curcumin_4h_R1 3 LVLAESPQPK 10 0 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312 E7EUR8 FAM193A Protein FAM193A 1 0 LVLAES(1)PQPK;LVLAES(1)PQPK;LVLAES(1)PQPK ;; 142.08 0.0013809 94600000 23260.8 18062.9 20163.4 20973.2 18929 22027 15716.5 9698.5 23325.3 19405.7 TRUE FALSE FALSE 21419.68314 19624.17659 20910.67334 20886.41846 18703.28404 17458.3519 16157.46269 12655.528 20766.57295 20080.04663 1.06671481 0.977297361 1.041365776 1.040157866 0.931436285 0.869437817 0.804652648 0.630253915 1.034189478 1 14.293475 -4.307849835 0.734727161 1.031327889 0.412351384 0.946360263 0.030156207 0.446155656 0.175576086 0.005832799 0.224376254 4.92E-05 4.307849835 -0.618976505 LVLEVAQHLGESTVR ddPTM_HeLa_Curcumin_4h_R1 1 LVLEVAQHLGESTVR 15 0 P06576 P06576 ATP5B "ATP synthase subunit beta, mitochondrial" 0 0 79.804 0.0086067 539540 172.61 158.81 165.65 162.37 329.44 509.65 222.74 228.58 308.98 189.77 FALSE FALSE TRUE 158.9477364 172.5368288 171.7891347 161.698156 325.5116432 403.9428451 228.9894849 298.2729897 275.085667 196.3644934 0.809452532 0.878655941 0.874848257 0.823459237 1.657690948 2.057107363 1.166145065 1.518976189 1.400893116 1 7.617390275 -5.760578139 24.99873895 0.896969562 1.60164375 0.578697923 0.261825052 9.044790001 262523.1226 0.030711996 0.058683275 1.74E-06 5.760578139 0.704674188 LVLLGESAVGK ddPTM_HeLa_Curcumin_4h_R1 1 LVLLGESAVGK 11 0 F8WCY6;F8VVZ0;K7ERI8;F8WD79;F8VUA5;F8VVK3;F8VWU4;F8VWZ7;F8VSF8;F8VPW9;K7ERQ8;P61020-2;P20339-2;P20339;P61020;P51148;P51148-2 F8WCY6 RAB5A;RAB5B;RAB5C Ras-related protein Rab-5B;Ras-related protein Rab-5A;Ras-related protein Rab-5C 0 0 99.815 0.010678 302960 273.2 405.8 315.04 436.58 265.46 266.59 246.79 151.38 322.64 366.58 FALSE FALSE TRUE 251.5759317 440.8755438 326.7156595 434.7735476 262.2945629 211.2962289 253.7142632 197.5350651 287.2471992 379.3186277 0.663231155 1.162282871 0.861322476 1.146196142 0.691488748 0.55704153 0.668868452 0.520762891 0.757271534 1 8.567266412 -5.535398376 24.87617167 0.886177129 0.596451408 0.50909356 0.153709253 168.1882512 334184.9065 0.025403308 0.050832493 2.91E-06 5.535398376 -0.289725722 LVLS(ph)PDAPDR ddPTM_HeLa_Curcumin_4h_R1 1 LVLSPDAPDR 10 0 Q9Y5B0-4;A0A0J9YWJ4;K7EJD2;A0A0J9YWB6;A0A0A0MR03;Q9Y5B0 Q9Y5B0-4 CTDP1 RNA polymerase II subunit A C-terminal domain phosphatase 1 0 LVLS(1)PDAPDR 95.094 0.015833 3762400 2603.9 2025.4 2417.9 2637.6 2587.4 3471 2810.8 2983.7 2741.6 2461.2 TRUE FALSE FALSE 2397.798567 2200.466551 2507.509501 2626.68631 2556.546945 2751.075474 2889.663483 3893.416395 2440.853339 2546.726517 0.941521813 0.86403724 0.98460101 1.031397087 1.003856098 1.080239851 1.134657948 1.528792499 0.95842774 1 11.31442833 -1 0.778605599 0.966868929 122.4049399 0.938363428 0.043089576 74.93628285 0.2692196 0.007514786 16028.77941 0.1 1 121.438071 LVLVLGDLHIPHR ddPTM_HeLa_Curcumin_4h_R1 1 LVLVLGDLHIPHR 13 0 F8VXU5;Q9UBQ0;Q9UBQ0-2 F8VXU5 VPS29 Vacuolar protein sorting-associated protein 29 0 0 108.56 0.00073024 602140 344.01 189.93 199.98 304.91 119.65 381.01 286.38 235.51 366.53 238.5 FALSE FALSE TRUE 316.7812455 206.3467029 207.3914347 303.6483632 118.2232519 301.9842311 294.415052 307.3159148 326.322576 246.7878572 1.283617634 0.836129886 0.840363205 1.230402365 0.479048091 1.223659197 1.192988404 1.245263516 1.322279709 1 7.947127601 LVNDDLMQTS(ph)FERMLSLK ddPTM_HeLa_Curcumin_4h_R1 1 LVNDDLMQTSFERMLSLK 18 1 Q6UB98-2;Q6UB98 Q6UB98-2 ANKRD12 Ankyrin repeat domain-containing protein 12 1 0 LVNDDLMQT(0.159)S(0.682)FERMLS(0.159)LK 43.37 0.020082 3799900 1504 1191.6 1215.4 1392.6 1159.8 1269 1238.7 1009.1 1561.3 1162.1 TRUE FALSE FALSE 1384.956813 1294.596594 1260.443793 1386.83779 1145.970142 1005.795095 1273.454588 1316.769945 1390.029296 1202.482889 1.151747627 1.076602924 1.048201022 1.153311871 0.953003285 0.83643194 1.059020964 1.095042563 1.155965968 1 10.23180065 -5.741976849 24.99246784 1.076887689 0.980424925 0.294848344 0.080767105 295.6564558 379660.0542 0.012798225 0.025567021 1.81E-06 5.741976849 -0.096462764 LVNHFVEEFK ddPTM_HeLa_Curcumin_4h_R1 2 LVNHFVEEFK 10 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 0 ; ; 114.89 0.00439 70816000 19769.4 16129.3 18114.6 16014.2 16994.8 28472 20395 21925 19516.7 17831.9 FALSE FALSE TRUE 18204.63113 17523.44482 18785.94301 15947.93748 16792.14811 22566.58625 20967.22881 28609.83157 17375.76684 18451.5572 0.986617603 0.949700052 1.018122363 0.864313907 0.910066718 1.223017982 1.136339258 1.550537511 0.9416965 1 14.17145496 -3.766312673 0.960060992 0.980413784 2.474001458 0.839145278 0.077216047 1.240712726 0.453979337 0.011322369 2.413209444 0.000171272 3.766312673 1.493587674 LVNHFVEEFKR ddPTM_HeLa_Curcumin_4h_R1 1 LVNHFVEEFKR 11 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 0 85.807 0.0063359 10630000 4310.9 3351.1 3553.9 3243.1 3209.6 11887 7228.1 7060.2 4516.4 3967 FALSE FALSE TRUE 3969.687716 3640.754152 3685.61066 3229.680912 3171.327616 9421.502206 7430.901033 9212.822479 4020.962219 4104.852955 0.967071844 0.886938994 0.897866672 0.786795763 0.772580078 2.295210647 1.810272162 2.244373326 0.979563035 1 12.00311483 -5.262633325 24.99994138 0.942527666 2.085984095 0.936992143 0.144352567 17.74805305 371630.4556 0.019870724 0.04688621 5.46E-06 5.262633325 1.143456429 LVNT(ph)T(ph)ITPEPEPKPQPNSR ddPTM_HeLa_Curcumin_4h_R1 1 LVNTTITPEPEPKPQPNSR 19 1 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 2 0 LVNT(0.861)T(0.876)IT(0.263)PEPEPKPQPNSR 62.475 0.011525 7433700 2072 1731.8 1859.4 2276.9 2057.4 2179.1 1450.4 973.82 1800.2 1771.5 TRUE FALSE FALSE 1907.999014 1881.489075 1928.311 2267.478791 2032.866849 1727.130096 1491.09432 1270.733235 1602.722564 1833.059493 1.040882209 1.026420082 1.051963129 1.236991379 1.109002112 0.942211697 0.813445677 0.693230765 0.874342906 1 10.84003789 -4.738327513 2.184961295 1.044212528 0.708536839 0.651287856 0.086924918 0.138030205 1.227815428 0.011021932 0.061637015 1.83E-05 4.738327513 -0.335675689 SCS(ph)PSSSVSR ddPTM_HeLa_Curcumin_4h_R1 2 SCSPSSSVSR 10 0 Q96S65 Q96S65 CSRNP1 Cysteine/serine-rich nuclear protein 1 1 0 S(0.034)CS(0.674)PS(0.027)S(0.07)S(0.196)VSR;S(0.036)CS(0.835)PS(0.037)S(0.088)S(0.004)VSR ; 126.66 0.0034134 9807300 5291.3 4062.2 4018.9 4132.4 4310.6 5851.7 3260.6 992.3 5152.6 4056.4 TRUE FALSE FALSE 4872.488022 4413.318467 4167.843969 4115.301224 4259.19891 4637.991458 3352.083661 1294.847702 4587.372671 4197.359598 1.160845981 1.051451124 0.992968049 0.980450001 1.014732908 1.104978344 0.798617222 0.30849101 1.09291867 1 12.03526635 -4.332657641 2.197740241 1.060669407 0.174915218 0.938352914 0.057862565 0.111899941 0.685277059 0.010575108 0.181145158 4.65E-05 4.332657641 -0.885754189 down LVPLLDTGDIIIDGGNSEYRDTTR ddPTM_HeLa_Curcumin_4h_R1 2 LVPLLDTGDIIIDGGNSEYRDTTR 24 1 P52209-2;P52209;K7EMN2;K7EM49 P52209-2 PGD "6-phosphogluconate dehydrogenase, decarboxylating" 0 0 ; ; 91.889 3.87E-05 21740000 2370.9 2202.04 2173.41 2465.2 2080.99 3133.87 2125.71 1906 2486.6 2494.8 FALSE FALSE TRUE 2183.240763 2392.374526 2253.958487 2454.999656 2056.175553 2483.870036 2185.351702 2487.130626 2213.826201 2581.494114 0.845727577 0.92674026 0.873121683 0.950999517 0.796506001 0.96218311 0.846545297 0.963446173 0.857575537 1 11.33399059 -9.474247584 1.17954386 1.000765831 0.890006807 0 0.06886206 0.381124301 0.938115503 0.034701787 0.008282416 3.36E-10 9.474247584 -0.110759024 LVPLLDTGDIIIDGGNSEYRDTTRR ddPTM_HeLa_Curcumin_4h_R1 1 LVPLLDTGDIIIDGGNSEYRDTTRR 25 2 P52209-2;P52209;K7EMN2;K7EM49 P52209-2 PGD "6-phosphogluconate dehydrogenase, decarboxylating" 0 0 53.059 0.0045769 8051900 1379.9 1101.7 1159.4 1203.9 892.67 1600.6 1184.4 1041.3 1954.8 1409.2 FALSE FALSE TRUE 1270.679459 1196.926039 1202.368384 1198.918581 882.0254933 1268.617518 1217.631076 1358.787576 1740.363331 1458.169595 0.871420899 0.820841446 0.824573759 0.822207914 0.604885396 0.870006837 0.83504078 0.931844678 1.193526004 1 10.50994281 -8.293747951 0.644023515 0.992947748 0.807873498 0.479353743 0.102835385 0.474676575 0.427786113 0.039706642 0.020772128 5.08E-09 8.293747951 -0.185074251 QLS(ph)SGVSEIR ddPTM_HeLa_Curcumin_4h_R1 2 QLSSGVSEIR 10 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 0 QLS(0.921)S(0.079)GVSEIR;QLS(0.99)S(0.009)GVS(0.001)EIR ; 132.86 0.0025149 15412700 1145.86 922.55 1175.31 977.04 904.57 1675.4 1619.73 6286.55 890.25 950.25 TRUE FALSE FALSE 1055.163972 1002.291111 1218.868023 972.9972674 893.7835935 1327.903154 1665.175265 8203.290155 792.5918023 983.2711168 1.073116004 1.019343591 1.239605234 0.989551356 0.908989981 1.350495435 1.693505724 8.342856833 0.806076563 1 9.941445455 -4.252884001 3.654094311 1.061426722 9.216984413 0.995305204 0.149387591 0.012570299 0.301802687 0.020218833 0.280870722 5.59E-05 4.252884001 8.155557691 up TS(ph)SISGPLS(ph)PAYTGQVPYNYNQLEGR ddPTM_HeLa_Curcumin_4h_R1 1 TSSISGPLSPAYTGQVPYNYNQLEGR 26 0 Q01082-3 Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 2 0 T(0.395)S(0.454)S(0.14)IS(0.03)GPLS(0.963)PAY(0.017)T(0.002)GQVPYNYNQLEGR 81.113 0.0002094 8363100 350.44 238.57 429.12 298.36 363.76 590.56 1012.8 5612.3 348.12 287.48 TRUE FALSE FALSE 322.7023042 259.1909278 445.0235647 297.1254654 359.4223996 468.071199 1041.216442 7323.464434 309.932107 297.4699086 1.084823355 0.871318141 1.496028848 0.998842091 1.208264733 1.573507725 3.500241241 24.61917734 1.04189398 1 8.216599926 -4.252502657 3.461931001 1.119095729 27.78186158 0.99888436 0.233740797 0.00973618 0.195608246 0.046356025 0.686267518 5.59E-05 4.252502657 26.66276585 up LVPVGYGIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 LVPVGYGIKK 10 1 P24534 P24534 EEF1B2 Elongation factor 1-beta 0 1 ; LVPVGYGIK(1)K;LVPVGYGIK(1)K 174.27 2.51E-13 12137800 11969.3 6484.1 9460.7 7045 9917.1 12880.4 11049.6 11206.4 8945.9 8721.9 FALSE TRUE FALSE 11021.91728 7044.556711 9811.321864 7015.849657 9798.84506 10208.85985 11359.62204 14623.17977 7964.557152 9024.985376 1.221267051 0.780561565 1.087128838 0.777380723 1.085746364 1.131177439 1.258685922 1.620299553 0.882500837 1 13.13970888 -4.238984137 1.494495194 1.055729385 1.863179357 0.621384036 0.147285933 0.681508249 1.315030266 0.02202105 0.82402016 5.77E-05 4.238984137 0.807449972 LVPVS(ph)PLPPK ddPTM_HeLa_Curcumin_4h_R1 2 LVPVSPLPPK 10 0 O95396 O95396 MOCS3 Adenylyltransferase and sulfurtransferase MOCS3;Molybdopterin-synthase adenylyltransferase;Molybdopterin-synthase sulfurtransferase 1 0 LVPVS(1)PLPPK;LVPVS(1)PLPPK ; 134.13 0.0023355 89115000 11502.8 9075.3 9216.4 9728.6 9529.7 11736.4 8798.8 9749.2 10878.4 9414.1 TRUE FALSE FALSE 10592.34124 9859.728493 9557.967892 9688.345631 9416.064552 9302.138344 9045.670647 12721.6862 9685.066736 9741.239274 1.087371016 1.01216367 0.98118603 0.994570132 0.966618752 0.954923504 0.928595468 1.305961782 0.994233533 1 13.24988961 -7.044188596 24.53707876 1.041706369 1.009734306 0 0.103111935 1425.562683 791584.8801 0.016327326 0.019997537 9.03E-08 7.044188596 -0.031972063 LVQAFQFTDK ddPTM_HeLa_Curcumin_4h_R1 3 LVQAFQFTDK 10 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 0 ;; ;; 157.24 0.00056548 29362800 1749.22 1350.81 1711.79 1593.63 1313.56 2600.84 1738.09 1889.79 1124.99 1249.01 FALSE FALSE TRUE 1610.767391 1467.567997 1775.230443 1587.035981 1297.896655 2061.396466 1786.856128 2465.978271 1001.581412 1292.413005 1.246325583 1.135525557 1.373578289 1.227963488 1.004242955 1.594998239 1.382573621 1.908041983 0.774970082 1 10.33585146 -1 0.41463288 1.112622352 14.23109755 0.647472271 0.182506095 28.07286709 0.323881943 0.035407723 307.3946261 0.1 1 13.11847519 LVQGSILK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 LVQGSILKK 9 1 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 1 LVQGSILK(1)K 132.01 0.00017071 3287700 1578.6 2005 1888.7 1631.8 2610.5 3353.7 2306.3 2885.2 3372.5 1763.9 FALSE TRUE FALSE 1453.652144 2178.303266 1958.696883 1625.048044 2579.371492 2658.104816 2371.008571 3764.884198 3002.545188 1825.195394 0.796436452 1.193463052 1.07314367 0.89034196 1.413202938 1.456339867 1.299043696 2.062729399 1.645054112 1 10.8338352 -1 0.384030702 0.907997534 16.5435854 0.380977286 0.284700001 19.53389479 0.235936466 0.043877273 230.7804346 0.1 1 15.63558787 LVQS(ph)PNSYFMDVK ddPTM_HeLa_Curcumin_4h_R1 2 LVQSPNSYFMDVK 13 0 P42677;H0YMV8;Q71UM5;C9JLI6 P42677 RPS27;RPS27L 40S ribosomal protein S27;40S ribosomal protein S27-like 1 0 LVQS(0.923)PNS(0.077)YFMDVK;LVQS(0.999)PNS(0.001)YFMDVK ; 182.37 0.00011307 40735000 5414.8 4420.6 4069.8 4915.2 4736.6 5392.4 3573.1 2265.5 4433.6 4426.9 TRUE FALSE FALSE 4986.212866 4802.696966 4220.630368 4894.862205 4680.119139 4273.955455 3673.351569 2956.240521 3947.245172 4580.734445 1.088518212 1.048455662 0.921387262 1.06857585 1.021696235 0.933028427 0.801913233 0.645363873 0.861705742 1 12.16136321 -4.505551406 1.181959199 1.03675892 0.551616314 0.713860231 0.070362054 0.259109051 0.397111754 0.00743715 0.137845786 3.12E-05 4.505551406 -0.485142606 LVRLS(ph)SDSFAR ddPTM_HeLa_Curcumin_4h_R1 1 LVRLSSDSFAR 11 1 A0A087WSV0;Q9HB09-3;Q9HB09 A0A087WSV0 BCL2L12 Bcl-2-like protein 12 1 0 LVRLS(0.76)S(0.224)DS(0.016)FAR 82.515 0.011065 6342000 1531.1 1226 1323.1 2111.6 1422.2 2114 1354.8 1008.5 2238.1 1444 TRUE FALSE FALSE 1409.911819 1331.969977 1372.13525 2102.862759 1405.241194 1675.53257 1392.812042 1315.987007 1992.586029 1494.178893 0.94360309 0.891439428 0.918320595 1.407370141 0.940477209 1.121373471 0.932158826 0.880742603 1.333565907 1 10.54513717 -10.58223553 14.97843762 1.068149198 0.991193183 0 0.183631171 1154369.756 10162133.99 2618876.814 0.020217849 2.62E-11 10.58223553 -0.076956015 LVS(ph)PEPPPK ddPTM_HeLa_Curcumin_4h_R1 2 LVSPEPPPK 9 0 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-4;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 LVS(1)PEPPPK;LVS(1)PEPPPK ; 94.692 0.016242 20480200 10519.2 10372.8 10171.2 10813.6 11856.8 10486.7 9237.1 9245.9 11205.3 8997.2 TRUE FALSE FALSE 9686.59422 11269.37861 10548.15362 10768.85619 11715.4154 8311.640211 9496.268166 12064.93235 9976.106624 9309.85203 1.040467044 1.210478811 1.133009804 1.156716149 1.258389002 0.892778981 1.020023534 1.295931698 1.071564467 1 13.18454252 -7.445782571 6.940528121 1.017635597 1.129441954 0.14090871 0.11085634 0.327117281 24.92630721 0.018716137 0.021246866 3.58E-08 7.445782571 0.111806357 LVS(ph)PEQPPK ddPTM_HeLa_Curcumin_4h_R1 1 LVSPEQPPK 9 0 O43491;O43491-4;E9PHY5;E9PK52;O43491-3;O43491-2;E9PII3;A0A2R8Y5B3 O43491 EPB41L2 Band 4.1-like protein 2 1 0 LVS(1)PEQPPK 89.561 0.020007 19471000 4341.3 3542.5 3500.9 3974.2 4351.7 4745.1 3857.5 2844.6 4542.5 3450.8 TRUE FALSE FALSE 3997.681524 3848.697915 3630.646434 3957.755813 4299.80882 3760.912772 3965.731068 3711.905445 4044.199115 3570.715043 1.119574504 1.077850758 1.016784143 1.108393071 1.204187052 1.053266006 1.110626589 1.039541212 1.132602032 1 11.80199729 -9.402254488 0.963730735 0.996082914 1.094352101 0 0.06389997 0.572917806 0.889091273 0.041394098 0.00898785 3.96E-10 9.402254488 0.098269187 QEKPAEKPAETPVAT(ph)SPTATDSTSGDSSR ddPTM_HeLa_Curcumin_4h_R1 2 QEKPAEKPAETPVATSPTATDSTSGDSSR 29 2 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 0 QEKPAEKPAET(0.005)PVAT(0.708)S(0.21)PT(0.038)AT(0.023)DS(0.005)T(0.005)S(0.005)GDS(0.001)SR;QEKPAEKPAET(0.003)PVAT(0.466)S(0.466)PT(0.053)AT(0.009)DS(0.001)T(0.001)S(0.001)GDSSR ; 96.221 3.83E-08 365201000 3430.2 3359 2907.3 3347.2 3044.1 4260.4 3912.5 9350.7 3913.5 2874.7 TRUE FALSE FALSE 3158.69605 3649.336993 3015.047096 3333.350173 3007.801096 3376.745015 4022.27422 12201.68538 3484.198841 2974.595611 1.061890913 1.226834659 1.013598986 1.120606163 1.011163025 1.135194647 1.352208752 4.101964428 1.171318491 1 11.53847784 -4.252470075 3.511262065 1.056536537 4.500444577 0.992458972 0.07817633 0.017367149 0.365308659 0.010952932 0.159615421 5.59E-05 4.252470075 3.44390804 up DYPAAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 DYPAAKR 7 1 H0YBT0;A0A087WUS5;P01106;P01106-2;A0A494C1T8 H0YBT0 MYC Myc proto-oncogene protein 0 1 ; DYPAAK(1)R;DYPAAK(1)R 102.77 0.0066068 0 4852.6 4017.3 4970.3 4121.9 4012.2 5647.1 3291 1407.36 4975.3 3864.2 FALSE TRUE FALSE 4468.51159 4364.537511 5154.50369 4104.84467 3964.357135 4475.827804 3383.336603 1836.457585 4429.522038 3998.480662 1.117552382 1.091548986 1.289115573 1.026601106 0.991465877 1.119382131 0.84615555 0.45928885 1.10780129 1 11.9652362 -4.350067946 2.202909599 1.073178918 0.361239625 0.844957926 0.083364174 0.155682844 0.985042769 0.012572422 0.199782936 4.47E-05 4.350067946 -0.711939293 down LVSFHDDS(ph)DEDLLHI ddPTM_HeLa_Curcumin_4h_R1 3 LVSFHDDSDEDLLHI 15 0 P11717 P11717 IGF2R Cation-independent mannose-6-phosphate receptor 1 0 LVSFHDDS(1)DEDLLHI;LVSFHDDS(1)DEDLLHI;LVSFHDDS(1)DEDLLHI ;; 118.16 0.00069061 11782000 3779.12 3119.56 3025.14 3097.61 5061.61 5649.53 2114 876.89 5422 4400.63 TRUE FALSE FALSE 3479.998664 3389.200866 3137.25435 3084.792911 5001.253607 4477.753795 2173.31315 1144.249724 4827.220165 4553.551565 0.764238335 0.744298339 0.688968667 0.677447673 1.098319309 0.983354143 0.477278695 0.25128731 1.060100033 1 12.15277651 -4.602959591 4.17941043 0.866278909 0.294908173 0.666284756 0.148492186 0.094107816 3.024950151 0.021887506 0.095593033 2.49E-05 4.602959591 -0.571370736 LVSPET(ph)EASEESLQFNLEKPATGER ddPTM_HeLa_Curcumin_4h_R1 2 LVSPETEASEESLQFNLEKPATGER 25 1 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 LVS(0.432)PET(0.567)EASEESLQFNLEKPATGER;LVS(0.031)PET(0.956)EAS(0.013)EESLQFNLEKPATGER ; 150.22 2.24E-08 17262400 1670.11 1471.2 1366.27 1528.73 1723.62 1841.79 1186.54 3298.7 1758.91 1687.29 TRUE FALSE FALSE 1537.919031 1598.363972 1416.905168 1522.40452 1703.066957 1459.781993 1219.831119 4304.458445 1565.961974 1745.923202 0.880862932 0.915483551 0.811550684 0.871976796 0.975453534 0.836108937 0.698673984 2.465434012 0.896924889 1 10.76977439 -4.256692239 24.99985885 0.909897473 2.465434643 0.968069077 0.086388011 65.60261837 345471.0338 0.013108812 0.142459618 5.54E-05 4.256692239 1.55553717 LVSPETEAS(ph)EES(ph)LQFNLEKPATGER ddPTM_HeLa_Curcumin_4h_R1 1 LVSPETEASEESLQFNLEKPATGER 25 1 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 LVS(0.114)PET(0.273)EAS(0.706)EES(0.906)LQFNLEKPATGER 55.02 0.0059572 7193600 1560.6 1201.3 1303.6 1419.8 1408.3 1984.6 1596.1 918.24 1357.4 1121.2 TRUE FALSE FALSE 1437.076863 1305.135019 1351.912563 1413.925244 1391.506942 1572.971589 1640.88227 1198.207149 1208.496616 1160.161617 1.238686785 1.124959661 1.165279512 1.218731273 1.199407843 1.355821091 1.414356627 1.032793304 1.041662298 1 10.18011008 -13.21626348 0.209003439 1.42E-09 1.269579546 0.378158609 0.102089526 30.75923572 0.427322749 12.56833914 0.093093254 6.08E-14 13.21626348 1.269579545 LVSPETEAS(ph)EESLQFNLEKPATGER ddPTM_HeLa_Curcumin_4h_R1 2 LVSPETEASEESLQFNLEKPATGER 25 1 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 LVSPET(0.054)EAS(0.946)EESLQFNLEKPATGER;LVS(0.002)PET(0.168)EAS(0.655)EES(0.175)LQFNLEKPATGER ; 140.48 6.12E-08 42470600 2950.5 2169.58 2561.4 3083.5 2836.2 2992.7 1885.05 2895.95 3159.1 2848.5 TRUE FALSE FALSE 2716.964812 2357.108828 2656.327737 3070.741294 2802.380167 2371.980285 1937.93943 3778.911824 2812.554634 2947.485163 0.921790836 0.799701677 0.901218357 1.041817388 0.950769898 0.80474715 0.657489121 1.282080016 0.954221812 1 11.52526884 -8.744178143 0.943609339 0.994040536 0.909493828 0.014499133 0.157021911 1.362626279 2.417071848 0.064296671 0.029446753 1.80E-09 8.744178143 -0.084546708 RPSTSQT(ph)VSTPAPVPVIESTEAIEAK ddPTM_HeLa_Curcumin_4h_R1 1 RPSTSQTVSTPAPVPVIESTEAIEAK 26 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 0 RPS(0.152)T(0.152)S(0.152)QT(0.18)VS(0.18)T(0.18)PAPVPVIES(0.001)T(0.001)EAIEAK 47.745 0.014778 8517900 722.66 664.37 657.34 538.33 645.69 970.89 1030.3 2685.7 749.1 869.46 TRUE FALSE FALSE 665.4606985 721.7951824 681.7015987 536.1025331 637.9905685 769.5164698 1059.207445 3504.557567 666.9256042 899.6736703 0.739668972 0.802285547 0.757720962 0.595885543 0.709135534 0.855328432 1.177324045 3.895365267 0.741297235 1 9.813257992 -4.252464244 3.322619877 0.829809505 4.342508105 0.985996813 0.110715105 0.034562051 0.60880174 0.020116206 0.312403318 5.59E-05 4.252464244 3.512698601 up LVSS(ph)DPEINTK ddPTM_HeLa_Curcumin_4h_R1 1 LVSSDPEINTK 11 0 Q9Y266 Q9Y266 NUDC Nuclear migration protein nudC 1 0 LVS(0.01)S(0.99)DPEINTK 161.99 0.0003146 8475900 2530.2 2059.6 1758.6 1964 2283.2 2510.7 1920.2 2347.5 2275.3 1547.6 TRUE FALSE FALSE 2329.932 2237.622647 1823.775263 1955.873488 2255.974331 1989.952519 1974.075644 3063.241943 2025.705283 1601.378985 1.454953526 1.397309861 1.13887798 1.221368275 1.408769787 1.242649328 1.232734826 1.912877571 1.264975563 1 10.64509906 -9.377175219 0.978124453 0.988781865 1.363072916 0.119786509 0.218939329 0.570622998 0.929422093 0.156424923 0.035801326 4.20E-10 9.377175219 0.374291051 LVSS(ph)PELGHDEFSTQALAR ddPTM_HeLa_Curcumin_4h_R1 1 LVSSPELGHDEFSTQALAR 19 0 O15020;O15020-2 O15020 SPTBN2 "Spectrin beta chain, non-erythrocytic 2" 1 0 LVS(0.187)S(0.813)PELGHDEFSTQALAR 71.756 0.004334 4173100 1217.8 860.32 869.1 1093.4 1066.5 620.08 612.31 584.7 1014.1 743.55 TRUE FALSE FALSE 1121.409845 934.6822273 901.3096105 1088.875801 1053.782684 491.4684183 629.4897707 762.9723384 902.8557672 769.3883072 1.457534296 1.214838097 1.171462579 1.415248699 1.369636989 0.638778122 0.818169141 0.991660948 1.173472171 1 9.587568094 -5.265492063 24.99896388 1.241360114 0.816399373 0.64489658 0.149714785 216.421484 1335000.049 0.028188177 0.065261868 5.43E-06 5.265492063 -0.424960741 LVSSDPEINTK ddPTM_HeLa_Curcumin_4h_R1 2 LVSSDPEINTK 11 0 Q9Y266 Q9Y266 NUDC Nuclear migration protein nudC 0 0 ; ; 191.4 3.88E-16 9409200 13949.3 11054.7 12829.9 12341.4 12017.7 14305.9 12135.4 12149.5 13683.5 11520.8 FALSE FALSE TRUE 12845.19819 12010.21901 13305.38738 12290.33456 11874.39678 11338.69508 12475.88666 15853.82662 12182.45428 11921.14694 1.077513619 1.00747177 1.116116381 1.030969135 0.996078384 0.95114129 1.04653409 1.32989105 1.021919648 1 13.54123542 -4.264035542 5.576658904 1.031984304 1.339856031 0.814675382 0.043267608 0.048295955 5.979771018 0.006541632 0.056469636 5.44E-05 4.264035542 0.307871727 LVTSGAESGNLNT(ph)SPSSNQTR ddPTM_HeLa_Curcumin_4h_R1 1 LVTSGAESGNLNTSPSSNQTR 21 0 Q8NHV4-2;Q8NHV4;Q8NHV4-3 Q8NHV4-2 NEDD1 Protein NEDD1 1 0 LVTSGAESGNLNT(0.682)S(0.058)PS(0.199)S(0.06)NQTR 334.98 1.62E-139 33313000 3137 2380.1 2070.4 2520.4 2757.6 2695 1578.6 1222.9 2694.7 2043.6 TRUE FALSE FALSE 2888.70314 2585.825238 2147.130845 2509.971253 2724.717421 2136.026621 1622.891267 1595.75658 2399.098152 2114.614948 1.36606579 1.222835032 1.015376746 1.186963733 1.288517053 1.010125566 0.767464199 0.754632224 1.134531918 1 11.04617927 -4.905586112 3.163971866 1.175897488 0.755444818 0.705833586 0.105566811 0.135113474 2.667930224 0.020853682 0.074204027 1.24E-05 4.905586112 -0.42045267 LVTSGAESGNLNTSPS(ph)SNQTR ddPTM_HeLa_Curcumin_4h_R1 1 LVTSGAESGNLNTSPSSNQTR 21 0 Q8NHV4-2;Q8NHV4;Q8NHV4-3 Q8NHV4-2 NEDD1 Protein NEDD1 1 0 LVTSGAESGNLNT(0.255)S(0.076)PS(0.646)S(0.023)NQTR 222.93 3.51E-23 61841000 4696.2 3435.7 3604.2 3749.7 3729.5 4578.3 3043.6 2144.6 4049.1 3829.7 TRUE FALSE FALSE 4324.490815 3732.666599 3737.774823 3734.184735 3685.028148 3628.708972 3128.995225 2798.478667 3604.92386 3962.78179 1.091276544 0.941930895 0.943219945 0.942313994 0.929909428 0.915697398 0.78959564 0.706190453 0.909695273 1 11.95229781 -3.148720732 0.384974525 1.040478841 1.60E-18 0.675175617 0.057023391 3.649870756 0.194830083 0.013953066 2.109470979 0.000710034 3.148720732 -1.040478841 LVTYYSCS(ph)YWK ddPTM_HeLa_Curcumin_4h_R1 1 LVTYYSCSYWK 11 0 D6RFZ2;J3KN75;Q0IIM8-2;Q0IIM8-3;Q0IIM8 D6RFZ2 TBC1D8B TBC1 domain family member 8B 1 0 LVTYYS(0.196)CS(0.732)Y(0.07)WK 103.31 0.0091803 19048000 652.76 488.37 788.27 713.49 658.72 1497.8 855.87 999.43 819.7 613.23 TRUE FALSE FALSE 601.0933572 530.5825267 817.4839796 710.5377674 650.8651942 1187.139396 879.8834087 1304.151606 729.7809608 634.5396969 0.94729039 0.836169162 1.288310225 1.11976882 1.025728095 1.870867027 1.386648327 2.055271897 1.150095044 1 9.309566612 -4.724826028 0.62423189 0.966358927 2.245439786 0.687814241 0.213014108 0.757395369 0.281859302 0.03440582 0.617466649 1.88E-05 4.724826028 1.279080859 LVVPASQCGSLIGK ddPTM_HeLa_Curcumin_4h_R1 2 LVVPASQCGSLIGK 14 0 Q15366;Q15366-2;Q15366-3;Q15366-6;Q15366-5;H3BRU6;F8VZX2;Q15366-8;Q15366-4;P57721;E9PFP8;J3QT27;F8W0G4;P57721-4;P57721-5;P57721-3;P57721-2;Q15366-7;F8VXH9;F8W1G6;H3BND9 Q15366 PCBP2;PCBP3 Poly(rC)-binding protein 2;Poly(rC)-binding protein 3 0 0 ; ; 150.14 0.00099648 7254000 2154.94 1726.22 1733.41 2118.93 2005.9 2405.76 1949.21 1303.63 2176.23 2159.59 FALSE FALSE TRUE 1984.374225 1875.426765 1797.651699 2110.162429 1981.980953 1906.778257 2003.899587 1701.100786 1937.503014 2234.635592 0.888007974 0.839253958 0.804449596 0.944298228 0.886936984 0.853283759 0.896745579 0.761243038 0.867033095 1 11.12582387 -8.788657154 0.557709184 1.01023337 0.857004801 0.031611039 0.062961111 0.567661208 0.320293139 0.042807663 0.012435542 1.63E-09 8.788657154 -0.153228569 LVVPATQCGSLIGK ddPTM_HeLa_Curcumin_4h_R1 2 LVVPATQCGSLIGK 14 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 0 0 ; ; 198.57 5.97E-13 4581800 2699.33 2199.59 2201.77 2642.22 2248.01 3023.71 2071.66 2021.24 2622.05 2792.16 FALSE FALSE TRUE 2485.675182 2389.712758 2283.369533 2631.287194 2221.203949 2396.558462 2129.785204 2637.506771 2334.417675 2889.187352 0.86033714 0.827122809 0.790315495 0.91073609 0.768798862 0.829492231 0.737157181 0.912888799 0.80798418 1 11.49644804 -8.78829061 0.474008857 1.022354865 0.814550803 0 0.079334549 0.591330832 0.233909892 0.056413151 0.015038933 1.63E-09 8.78829061 -0.207804062 LVVVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 LVVVKK 6 1 Q9BW85 Q9BW85 CCDC94 Coiled-coil domain-containing protein 94 0 1 LVVVK(1)K 106.84 0.010351 6330200 7499.7 7498.3 7385.7 6305.5 6884.4 11147 8880.8 9054.8 8333.6 6983.8 FALSE TRUE FALSE 6906.090831 8146.41964 7659.420539 6279.409512 6802.308026 8834.986547 9129.971347 11815.56684 7419.42493 7226.48653 0.955663697 1.12730019 1.059909336 0.86894364 0.941302249 1.222583964 1.263403911 1.635036167 1.026698784 1 12.81907867 -4.28708473 1.091488869 0.986186406 1.922681851 0.852634637 0.08089852 0.426047912 0.412361017 0.012252181 0.454124931 5.16E-05 4.28708473 0.936495445 LVVVLCNLKPQK ddPTM_HeLa_Curcumin_4h_R1 1 LVVVLCNLKPQK 12 1 P54577 P54577 YARS "Tyrosine--tRNA ligase, cytoplasmic;Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed" 0 0 94.363 0.0074046 3039000 2713.6 1952 2172.6 2057.7 2023.7 4325.3 2822.2 3065.4 2656.3 2353.6 FALSE FALSE TRUE 2498.815697 2120.722182 2253.118467 2049.185783 1999.568699 3428.184024 2901.383336 4000.026349 2364.910536 2435.387425 1.026044428 0.870794585 0.925158126 0.84142086 0.821047476 1.407654482 1.191343647 1.642459967 0.971061323 1 11.24993558 -5.249815629 24.58838904 0.970796855 1.391571851 0.755466189 0.125875504 251.0876433 531138.5661 0.017757723 0.044844611 5.63E-06 5.249815629 0.420774996 LWAPDS(ph)PNR ddPTM_HeLa_Curcumin_4h_R1 1 LWAPDSPNR 9 0 E5RIM3;Q9Y263 E5RIM3 PLAA Phospholipase A-2-activating protein 1 0 LWAPDS(1)PNR 101.3 0.012371 4946300 2360.7 1932.2 2134 1780 2302.9 2537.5 1807.8 1891.4 2046.6 2058.1 TRUE FALSE FALSE 2173.848104 2099.210758 2213.087917 1772.634832 2275.439422 2011.193896 1858.522003 2468.079153 1822.0931 2129.618822 1.020768638 0.985721359 1.039194383 0.832371884 1.068472629 0.944391492 0.872701717 1.158930006 0.855595885 1 11.05637951 LWAQDGSEDEPPKDS(ph)DGEDPETAAVGCR ddPTM_HeLa_Curcumin_4h_R1 2 LWAQDGSEDEPPKDSDGEDPETAAVGCR 28 1 A0A087WXB3;A0A087X223;A0A087WYW1;Q96NU1-4;Q96NU1-5;H7C3J6;A0A087X1J5;Q96NU1-1;Q96NU1-2;H7BY14;A0A087WYU3;Q96NU1-6;Q96NU1 A0A087WXB3;H7BY14 SAMD11 Sterile alpha motif domain-containing protein 11 1 0 LWAQDGS(0.003)EDEPPKDS(0.997)DGEDPETAAVGCR;LWAQDGS(0.004)EDEPPKDS(0.963)DGEDPET(0.033)AAVGCR ; 105.32 1.12E-09 168382000 2698.11 2407.81 2629.29 2606.83 2274.32 3190.5 2542.06 1094.71 2766.1 2750 TRUE FALSE FALSE 2484.551746 2615.930367 2726.7338 2596.043628 2247.200219 2528.754336 2613.383362 1428.48204 2462.66575 2845.562295 0.873132087 0.919301739 0.958240768 0.912313054 0.789720971 0.888665955 0.918406659 0.502003432 0.865440814 1 11.47449805 -4.261237697 7.413634889 0.922572992 0.497134336 0.815621403 0.056472367 0.035229472 17.73296583 0.009209806 0.074368711 5.48E-05 4.261237697 -0.425438656 LWDCETGK ddPTM_HeLa_Curcumin_4h_R1 1 LWDCETGK 8 0 Q13347;Q5TFK1 Q13347 EIF3I Eukaryotic translation initiation factor 3 subunit I 0 0 98.458 0.014827 1749200 652.54 786.69 688.71 608.47 671.05 1165.7 576.21 752.36 861.77 678.59 FALSE FALSE TRUE 600.8907704 854.6879782 714.2341985 605.9523124 663.048167 923.9206799 592.3769018 981.7511006 767.235987 702.170952 0.855761362 1.217207826 1.017179928 0.862969781 0.944283105 1.315805898 0.843636297 1.398165358 1.09266267 1 9.455678505 LWDLTTGTTTR ddPTM_HeLa_Curcumin_4h_R1 2 LWDLTTGTTTR 11 0 P63244;D6RHH4;D6R9L0;J3KPE3;D6RAU2;E9PD14;D6RFX4;D6R9Z1;H0YAF8;H0Y8W2;D6RFZ9 P63244 GNB2L1 "Guanine nucleotide-binding protein subunit beta-2-like 1;Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed" 0 0 ; ; 199.46 8.31E-17 3882500 1043.58 1205.39 1034.49 1318.41 1189.63 1243.46 1271.36 1529.09 1225.09 959.04 FALSE FALSE TRUE 960.9795418 1309.57854 1072.829109 1312.954769 1175.444439 985.5523793 1307.03094 1995.302502 1090.700692 992.3665686 0.96837154 1.319652014 1.081081471 1.323054212 1.184486133 0.993133395 1.317084816 2.010650666 1.099090524 1 9.954729324 -1.612135716 0.965859328 1.044066896 200 0.769925187 0.140052464 117.1784833 0.690434725 0.023603173 50883.12733 0.024426671 1.612135716 198.9559331 up LWEDS(ph)AGEK ddPTM_HeLa_Curcumin_4h_R1 1 LWEDSAGEK 9 0 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-7;Q86U86-3;Q86U86-2;H0Y5B5 Q86U86-8 PBRM1 Protein polybromo-1 1 0 LWEDS(1)AGEK 121.68 0.0058003 5661700 2133.8 1916.1 2209.7 1789.9 2171.2 1951.8 2000.5 1369.4 2172.5 2016.6 TRUE FALSE FALSE 1964.907478 2081.719146 2291.593426 1782.493868 2145.309858 1546.974679 2056.628646 1786.923756 1934.182185 2086.6767 0.941644424 0.997624187 1.098202432 0.854226181 1.028098822 0.741358102 0.985600043 0.85634912 0.926919913 1 11.02699138 -5.298224705 24.9943463 0.977578986 0.873551988 0.295548496 0.082101331 522.7844435 355213.0783 0.010585698 0.023671035 5.03E-06 5.298224705 -0.104026998 LWHLDPDTEYEIR ddPTM_HeLa_Curcumin_4h_R1 2 LWHLDPDTEYEIR 13 0 H0YDP9;Q5TG12;E9PGC5;Q15262;Q15262-2;Q15262-3;Q15262-4 H0YDP9 PTPRK Protein-tyrosine-phosphatase;Receptor-type tyrosine-protein phosphatase kappa 0 0 ; ; 174.9 0.00016926 10300500 5316.8 3826.3 3681.1 3983 3727 4580.6 3311.8 2521.6 4569.5 3980.8 FALSE FALSE TRUE 4895.96967 4157.028322 3817.524804 3966.519401 3682.557959 3630.531926 3404.720195 3290.424232 4068.237282 4119.132504 1.18859242 1.009199951 0.92677883 0.962950184 0.894012988 0.881382651 0.826562436 0.798814855 0.987644189 1 12.00812482 -6.27644166 0.994978445 1.086653955 0.83911474 0.624769472 0.064518009 0.251314882 0.492622325 0.014677059 0.030953415 5.29E-07 6.27644166 -0.247539215 LWQTVVGK ddPTM_HeLa_Curcumin_4h_R1 2 LWQTVVGK 8 0 Q9Y3F4-2;Q9Y3F4;H0YH33 Q9Y3F4-2 STRAP Serine-threonine kinase receptor-associated protein 0 0 ; ; 114.28 0.004124 1080100 1324.64 1015.81 1281.97 1310.71 915.22 1225.38 1276.51 1098.88 1329.48 1062.03 FALSE FALSE TRUE 1219.793346 1103.61209 1329.480936 1305.286629 904.3065992 971.2223751 1312.325435 1433.923453 1183.63937 1098.935463 1.109977234 1.004255597 1.209789819 1.187773689 0.822893272 0.883784724 1.194178802 1.304829538 1.077078145 1 10.10189095 -5.712958019 0.010859909 3.05E-06 2.17931367 0.040240368 0.141863793 7722.355974 23.93714661 2302.871985 2501.79202 1.94E-06 5.712958019 2.179310617 LWSLDSDEPVADIEGHTVR ddPTM_HeLa_Curcumin_4h_R1 1 LWSLDSDEPVADIEGHTVR 19 0 O43172;O43172-2 O43172 PRPF4 U4/U6 small nuclear ribonucleoprotein Prp4 0 0 88.283 0.0019384 2373600 970.86 718.08 805.58 644.11 629.59 1468.2 1001.5 997.01 1031.7 710.46 FALSE FALSE TRUE 894.0154066 780.1476355 835.4355035 641.4448435 622.0825504 1163.67877 1029.599395 1300.993759 918.5250912 735.1484321 1.216101902 1.061211044 1.136417446 0.872537865 0.846199928 1.582916754 1.400532667 1.769702148 1.249441679 1 9.52189176 -5.24567362 24.7257066 1.071328837 1.565998817 0.725898319 0.148819137 302.0088565 473644.5148 0.021198159 0.0538325 5.68E-06 5.24567362 0.49466998 LWSVHGQK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 LWSVHGQKR 9 1 A0A5F9ZI22;A0A5F9ZH29;A0A5K1VW85;O75419-2;O75419;O75419-3 A0A5F9ZI22 CDC45 Cell division control protein 45 homolog 0 1 LWSVHGQK(1)R 76.478 0.018749 1437200 141.37 152.22 0 113.04 126.03 0 126.12 0 177.32 148.02 FALSE TRUE FALSE 130.1804153 165.3772185 0 112.5722704 124.5271746 0 129.6585878 0 157.8684396 153.163684 0.849943093 1.079741713 0 0.73498017 0.813033294 0 0.8465361 0 1.030717175 1 7.258930456 -5.950539207 0.293986075 1.039237646 0.109404254 0.349941737 0.344899654 2.558621032 0.37825196 0.219520212 0.833130445 1.12E-06 5.950539207 -0.929833392 LY(ph)HLQT(ph)NK ddPTM_HeLa_Curcumin_4h_R1 1 LYHLQTNK 8 0 Q8NCW6 Q8NCW6 GALNT11 Polypeptide N-acetylgalactosaminyltransferase 11 2 0 LY(1)HLQT(1)NK 75.738 0.016796 60921000 3239.5 2827.6 2955.7 3098.4 3051.2 3820.8 3053.6 2789.7 3511.6 3146.3 TRUE FALSE FALSE 2983.090157 3072.005144 3065.240842 3085.579642 3014.816433 3028.323011 3139.275798 3640.266688 3126.386266 3255.633691 0.916285565 0.943596681 0.941518959 0.947766222 0.926030604 0.930179283 0.964259525 1.118143819 0.960300379 1 11.66872267 -4.264187068 4.588891243 0.951974533 1.128278674 0.839272587 0.022361536 0.080858774 4.454368782 0.004595504 0.045602733 5.44E-05 4.264187068 0.176304141 ASLVS(ph)EEEEDEEEDKATPR ddPTM_HeLa_Curcumin_4h_R1 3 ASLVSEEEEDEEEDKATPR 19 1 Q96GN5-5;Q96GN5-2;Q96GN5;C9IZR6;Q96GN5-4;C9J8L0 Q96GN5-5 CDCA7L Cell division cycle-associated 7-like protein 1 0 AS(0.071)LVS(0.929)EEEEDEEEDKATPR;AS(0.004)LVS(0.996)EEEEDEEEDKATPR;AS(0.007)LVS(0.993)EEEEDEEEDKATPR ;; 145.02 6.14E-05 225741000 6704.1 4971.4 6428.1 5526.6 6904.2 6264.5 4392.2 1898.03 5444.2 5243.5 TRUE FALSE FALSE 6173.463411 5401.105664 6666.331041 5503.732394 6821.871924 4965.172085 4515.433311 2476.73061 4846.984881 5425.711235 1.137816434 0.995465005 1.228655701 1.014379895 1.257323073 0.915119119 0.83222883 0.456480359 0.893336315 1 12.40559655 -4.330117455 1.446922745 1.079811683 0.265603853 0.738717204 0.111124374 0.326649489 0.671313553 0.01367636 0.367657852 4.68E-05 4.330117455 -0.81420783 down LYADS(ph)DSGDDS(ph)DKR ddPTM_HeLa_Curcumin_4h_R1 1 LYADSDSGDDSDKR 14 1 O43896 O43896 KIF1C Kinesin-like protein KIF1C 2 0 LY(0.002)ADS(0.955)DS(0.044)GDDS(0.998)DKR 98.253 0.009315 2492500 1159.1 813.23 970.33 828.49 1068.3 970.41 898.36 495.98 929.63 948.19 TRUE FALSE FALSE 1067.356012 883.5219775 1006.291283 825.0619279 1055.56122 769.1360272 923.5655638 647.2020188 827.6519148 981.1395319 1.087873821 0.900505941 1.025635244 0.840922113 1.075852298 0.783921147 0.941319286 0.659643198 0.843561887 1 9.938314512 -3.087777455 0.40975515 1.035221392 1.53E-15 0.287793021 0.109741845 6.674844722 0.370423549 0.021224694 4.176429623 0.000817001 3.087777455 -1.035221392 LYAGAILEVCGK ddPTM_HeLa_Curcumin_4h_R1 1 LYAGAILEVCGK 12 0 A0A087WXL0;A0A087X1G7 A0A087WXL0 15-Sep 0 0 103.55 0.0057301 431370 369.53 595.49 561.07 383.71 573.49 928.77 726.38 862.4 411.43 243.47 FALSE FALSE TRUE 340.2813106 646.9615021 581.8637478 382.1223097 566.6515063 736.1326326 746.7602678 1125.34179 366.2971583 251.9305644 1.350694829 2.568015134 2.309619514 1.516776302 2.249236839 2.921966354 2.964151133 4.466872818 1.453960774 1 7.976882351 -1 0.231582038 0.952686896 19.15544469 0.791392552 0.445504167 13.74815791 0.167623176 0.289366403 96.07632919 0.1 1 18.20275779 up LYCPVEFSK ddPTM_HeLa_Curcumin_4h_R1 2 LYCPVEFSK 9 0 P52788;P52788-2 P52788 SMS Spermine synthase 0 0 ; ; 111.04 0.0032829 1514430 1642.47 1064.45 1346.23 1517.6 1506.62 1644.33 1366.08 1216.32 1342.47 1460.92 FALSE FALSE TRUE 1512.466766 1156.456315 1396.122468 1511.320573 1488.654541 1303.277423 1404.408528 1587.170369 1195.2044 1511.686861 1.000515917 0.765010496 0.923552691 0.999757696 0.984763828 0.862134517 0.929034024 1.049933296 0.790642844 1 10.56194361 -7.430086998 24.95536921 1.000262394 0.928833265 0 0.099034867 74.28151464 19973.30092 0.012411406 0.014192957 3.71E-08 7.430086998 -0.071429129 LYDAYELK ddPTM_HeLa_Curcumin_4h_R1 2 LYDAYELK 8 0 P08758;D6RBL5;E9PHT9 P08758 ANXA5 Annexin A5;Annexin 0 0 ; ; 117.04 0.0030467 10166400 9985.7 7899.5 9814.2 7547.7 8081 11712.7 10399.3 9470.2 7983.8 6603.5 FALSE FALSE TRUE 9195.321308 8582.297581 10177.92289 7516.469617 7984.639353 9283.353991 10691.07637 12357.62038 7107.997114 6832.971133 1.345728107 1.256012562 1.489531082 1.10002947 1.168545746 1.358611621 1.564630694 1.808528112 1.040249838 1 12.73829732 -1 0.442389057 1.167883348 15.06161559 0.671580503 0.138610877 39.05434976 0.428057747 0.036325099 492.060934 0.1 1 13.89373224 LYDIDVAK ddPTM_HeLa_Curcumin_4h_R1 2 LYDIDVAK 8 0 K7EMA7;H7BY10;K7EJV9;K7ERT8;A8MUS3;P62750 K7EMA7 RPL23A 60S ribosomal protein L23a 0 0 ; ; 111.04 0.0059256 8650900 13077.3 10472.7 12423.9 11786 10932.2 14624.1 11285.5 10994.7 13831.7 12356.8 FALSE FALSE TRUE 12042.21791 11377.91352 12884.34066 11737.23265 10801.84066 11590.89681 11602.14076 14346.93342 12314.39712 12786.19788 0.941813823 0.889859021 1.007675682 0.91796113 0.844804746 0.906516301 0.907395683 1.122064084 0.963100777 1 13.64229971 -8.905487238 0.776746493 0.999710188 0.936431219 0.030432232 0.073082186 1.230001384 1.387850384 0.044170985 0.01471056 1.24E-09 8.905487238 -0.063278969 LYDSS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 LYDSSPSR 8 0 E9PP00;Q9C0D7;Q9C0D7-2 E9PP00 ZC3H12C Probable ribonuclease ZC3H12C 1 0 LYDS(0.062)S(0.938)PSR;LYDS(0.125)S(0.874)PSR ; 138.06 0.0034488 33945000 6964.7 5425.5 5534.4 5424.1 6217.4 7043.5 4349.6 2288.85 6724 5276.5 TRUE FALSE FALSE 6413.436646 5894.456044 5739.509733 5401.656511 6143.261566 5582.598703 4471.63807 2986.709828 5986.394023 5459.857982 1.17465265 1.079598785 1.051219602 0.989340113 1.125168747 1.02248057 0.819002634 0.547030681 1.096437681 1 12.41464771 -4.425352215 1.655993649 1.07799218 0.450094276 0.909380037 0.052321219 0.19291799 0.644486929 0.010301374 0.17360807 3.76E-05 4.425352215 -0.627897904 LYEEDDLDRLEQMEDSEGTVR ddPTM_HeLa_Curcumin_4h_R1 2 LYEEDDLDRLEQMEDSEGTVR 21 1 Q86W92-2;H0YFE4;Q86W92-3;Q86W92-4;Q86W92 Q86W92-2;Q86W92-3 PPFIBP1 Liprin-beta-1 0 0 ; ; 124.45 8.31E-05 15098200 2051.6 1384 1836.65 2149.41 1798.91 2286.6 1364.56 850.44 2263.21 1834.21 FALSE FALSE TRUE 1889.213695 1503.626793 1904.717865 2140.516311 1777.459173 1812.333385 1402.845881 1109.735241 2014.941525 1897.948661 0.995397681 0.792237864 1.003566589 1.127805169 0.936515939 0.954890626 0.739137949 0.584702455 1.061641743 1 10.89022525 -4.582429405 1.894466925 0.98905599 0.561663367 0.727908447 0.081690491 0.169000898 0.96277713 0.011173433 0.101200765 2.62E-05 4.582429405 -0.427392623 LYEEGSNKR ddPTM_HeLa_Curcumin_4h_R1 1 LYEEGSNKR 9 1 P25788-2;P25788 P25788-2 PSMA3 Proteasome subunit alpha type-3 0 0 87.181 0.0079747 1510800 1642.4 1734.8 1383.2 1178.5 1357.1 2388.1 1507.2 1502.7 1458.2 1406.3 FALSE FALSE TRUE 1512.402307 1884.748382 1434.462609 1173.623679 1340.917469 1892.781141 1549.487976 1960.866312 1298.239108 1455.16882 1.039331166 1.295209432 0.985770578 0.806520634 0.921485844 1.300729588 1.064816641 1.347518092 0.892157041 1 10.50697082 -5.259057835 24.99891467 1.01581579 1.220400962 0.385845868 0.139491461 191.8079564 2013380.274 0.019014126 0.046051859 5.51E-06 5.259057835 0.204585172 LYENFISEFEHR ddPTM_HeLa_Curcumin_4h_R1 2 LYENFISEFEHR 12 0 E9PPD2;E9PQG3;J3KNQ3;A0A087WUL9;Q9UNM6 E9PPD2 PSMD13 26S proteasome non-ATPase regulatory subunit 13 0 0 ; ; 105.95 0.0040028 6704000 7965.4 7357.3 7805.9 6672.9 9908.5 10919.5 8090.5 7737.7 6855 6910.5 FALSE FALSE TRUE 7334.930185 7993.232229 8095.193521 6645.289308 9790.347609 8654.672612 8317.497656 10096.88911 6103.02365 7150.639361 1.025772636 1.117834619 1.132093665 0.929327991 1.369156954 1.210335492 1.163182372 1.412026058 0.853493421 1 12.80385653 -1 0.22985278 0.982519827 3.14292969 0.577657627 0.110322051 24.71338494 0.300529331 0.063285117 20.29254597 0.1 1 2.160409862 LYEQLSGK ddPTM_HeLa_Curcumin_4h_R1 1 LYEQLSGK 8 0 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 0 0 128.38 0.0018192 4664200 2527.6 1604.9 2247.1 2018.4 2178.6 3343.6 2738.5 2475 2626.9 2077.8 FALSE FALSE TRUE 2327.537793 1743.620405 2330.379503 2010.048396 2152.621618 2650.09967 2815.33494 3229.616107 2338.735642 2150.003395 1.082574008 0.810984954 1.083895731 0.934904754 1.001217776 1.232602551 1.309456044 1.502144654 1.087782302 1 11.07012322 -4.789690809 1.483650681 1.015085747 1.49529173 0.791343467 0.085971637 0.174992884 0.626855592 0.012382206 0.092440732 1.62E-05 4.789690809 0.480205984 RKTS(ph)DANETEDHLESLICK ddPTM_HeLa_Curcumin_4h_R1 1 RKTSDANETEDHLESLICK 19 2 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 0 RKT(0.204)S(0.655)DANET(0.139)EDHLES(0.002)LICK 61.821 0.0057466 38377000 3874.9 2833.8 3163.9 3225 3564.4 5425.4 6252.2 11094 4794.3 5850.6 TRUE FALSE FALSE 3568.197576 3078.741045 3281.156917 3211.655805 3521.896858 4300.110883 6427.619905 14476.50953 4268.377285 6053.907915 0.589404006 0.508554324 0.541989895 0.530509524 0.581755935 0.710303319 1.061730703 2.391266886 0.705061482 1 12.56365102 -4.252187885 2.502714125 0.721614483 2.781886379 0.921229299 0.152057679 0.151241151 1.148550647 0.030511928 0.667305705 5.60E-05 4.252187885 2.060271896 up LYGPS(ph)SVSFADDFVR ddPTM_HeLa_Curcumin_4h_R1 2 LYGPSSVSFADDFVR 15 0 P50454;E9PR70;E9PPV6;E9PK86;E9PMI5;E9PQ34;E9PJH8;E9PIG2;E9PRS3;E9PNX1 P50454 SERPINH1 Serpin H1 1 0 LYGPS(0.478)S(0.478)VS(0.043)FADDFVR;LYGPS(0.495)S(0.495)VS(0.009)FADDFVR ; 142.95 0.00051176 7455200 1526.79 1242.58 1328.79 1022.82 1546.56 1386.48 1198.12 991.54 1741.82 1078.02 TRUE FALSE FALSE 1405.94296 1349.983078 1378.036126 1018.587842 1528.118282 1098.908419 1231.736023 1293.855982 1550.746704 1115.481115 1.26039154 1.210224952 1.235373785 0.913137684 1.36991856 0.985143007 1.104219521 1.15990846 1.390204355 1 10.12345037 -4.180092053 16.94983432 1.13091504 1.159925478 0 0.156475989 18984.24977 3943947.873 0.019259574 61.03383083 6.61E-05 4.180092053 0.029010438 LYINHT(ph)PPPLSK ddPTM_HeLa_Curcumin_4h_R1 1 LYINHTPPPLSK 12 0 H0Y7U4;A0A0C4DG98;Q8NI27-2;Q8NI27;B7ZBA0;H0Y594 H0Y7U4 THOC2 THO complex subunit 2 1 0 LYINHT(1)PPPLSK 157.56 0.00082833 26041000 3625.3 3386.8 2844.3 3469.1 3570.5 4767.6 4386.7 1200.1 3458.7 3391.6 TRUE FALSE FALSE 3338.35368 3679.539901 2949.71226 3454.745783 3527.924119 3778.746018 4509.778996 1566.004965 3079.289263 3509.457848 0.951244843 1.048463911 0.840503687 0.984410109 1.005261859 1.076732128 1.285035807 0.446224184 0.877425915 1 11.77703246 -1.000080005 0.005323515 1.874914311 0.00015324 0 0.204332436 346566.9968 144.2911974 23496.62772 27464.8266 0.09998158 1.000080005 -1.874761071 LYKS(ph)EPELTTVAEVDESNGEEK ddPTM_HeLa_Curcumin_4h_R1 1 LYKSEPELTTVAEVDESNGEEK 22 1 A0JP02;B4DJX4;Q9HAU0-8;Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6 A0JP02 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 0 LY(0.001)KS(0.913)EPELT(0.084)T(0.002)VAEVDESNGEEK 123.68 4.36E-06 18104000 3707.8 3156.3 3341.7 2987.6 3955 3990.9 3124.1 1614.4 3135.2 2889.2 TRUE FALSE FALSE 3414.323718 3429.116508 3465.546342 2975.238103 3907.839208 3163.142353 3211.753838 2106.623128 2791.276404 2989.599485 1.142067268 1.147015353 1.159200876 0.995196219 1.307144729 1.058048869 1.074309069 0.704650619 0.933662324 1 11.5457365 -4.258526613 4.758937611 1.091538683 0.681770852 0.572442119 0.100206001 0.096638581 6.104279403 0.012796888 0.131054498 5.51E-05 4.258526613 -0.409767832 LYNNHEIR ddPTM_HeLa_Curcumin_4h_R1 2 LYNNHEIR 8 0 O60506-4;O60506-3;O60506-2;O60506;B7Z645;O60506-5 O60506-4 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 0 ; ; 96.948 0.0046033 5307900 3670.3 3193.5 2715.3 2717.1 2797.1 4001.1 3437.6 3075.2 3335.4 2947.3 FALSE FALSE TRUE 3379.791882 3469.53191 2815.931407 2705.85736 2763.746409 3171.226758 3534.049804 4012.814324 2969.514965 3049.718456 1.108230786 1.137656463 0.923341432 0.887248249 0.906230017 1.039842466 1.158811823 1.315798288 0.973701346 1 11.57446035 -4.470187683 2.366401341 1.026414146 1.327439595 0.591681432 0.082067546 0.254506921 2.263194231 0.013430846 0.129163007 3.39E-05 4.470187683 0.30102545 LYNSEESRPYT(ph)NK ddPTM_HeLa_Curcumin_4h_R1 1 LYNSEESRPYTNK 13 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 0 LYNSEES(0.003)RPYT(0.997)NK 156.6 0.0034168 16156000 1011.8 1625.4 1339.5 1670.3 1367.3 2151.8 1915.3 1802 1536.8 1768.1 TRUE FALSE FALSE 931.7149624 1765.892333 1389.143048 1663.388741 1350.995841 1705.492424 1969.038163 2351.421505 1368.216885 1829.541343 0.509261496 0.965210401 0.759284863 0.909183467 0.738434168 0.932196712 1.07624688 1.285251909 0.747846934 1 10.8372663 -4.409308214 1.052355136 0.783096908 1.468717213 0.573341827 0.133224109 1.053891131 1.079142818 0.028721813 0.757646836 3.90E-05 4.409308214 0.685620304 LYPPGDEEEAELADS(ph)SGLYHEGSPSPGSPWK ddPTM_HeLa_Curcumin_4h_R1 1 LYPPGDEEEAELADSSGLYHEGSPSPGSPWK 31 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 0 LYPPGDEEEAELADS(0.394)S(0.117)GLY(0.139)HEGS(0.248)PS(0.07)PGS(0.032)PWK 67.388 6.34E-05 6761700 1479.3 1316.8 995.33 1096.2 1650.1 2045 1859.9 1284.8 1490.1 1269.7 TRUE FALSE FALSE 1362.211844 1430.618324 1032.217805 1091.664215 1630.423635 1620.843948 1912.083788 1676.529606 1326.639758 1313.82198 1.03683137 1.08889815 0.785660326 0.830907255 1.24097759 1.233686125 1.455359871 1.276070602 1.009756099 1 10.35955409 -5.60245271 5.791540424 0.993063819 1.320124983 0.719378778 0.104390549 0.092250525 5.126860758 0.016015542 0.03242644 2.50E-06 5.60245271 0.327061163 LYPPGDEEEAELADSSGLYHEGSPS(ph)PGSPWK ddPTM_HeLa_Curcumin_4h_R1 1 LYPPGDEEEAELADSSGLYHEGSPSPGSPWK 31 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 0 LYPPGDEEEAELADS(0.006)S(0.005)GLY(0.058)HEGS(0.203)PS(0.636)PGS(0.092)PWK 69.47 5.17E-05 14175000 3533.5 3552.9 2813 2742 4894.3 8900.5 5462.7 3870.4 4925 3437.6 TRUE FALSE FALSE 3253.819746 3859.996845 2917.252255 2730.654331 4835.938669 7054.435971 5615.96866 5050.467143 4384.739822 3557.056344 0.91475069 1.085166067 0.820131022 0.767672498 1.359533896 1.983223005 1.578824769 1.419844572 1.232687761 1 11.79646811 -5.560334674 5.09158403 0.947315733 1.657605643 0.749790553 0.180001738 0.054794919 3.457493412 0.022103806 0.045797711 2.75E-06 5.560334674 0.710289911 LYPPGDEEEAELADSSGLYHEGSPSPGS(ph)PWK ddPTM_HeLa_Curcumin_4h_R1 1 LYPPGDEEEAELADSSGLYHEGSPSPGSPWK 31 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 0 LYPPGDEEEAELADS(0.004)S(0.018)GLY(0.25)HEGS(0.177)PS(0.178)PGS(0.373)PWK 116.62 2.62E-13 4468700 3914.2 2892.2 2761.9 2567.7 4411.9 9271.9 5204.2 2849.9 4973.2 3322 TRUE FALSE FALSE 3604.38694 3142.188881 2864.258444 2557.075538 4359.290974 7348.803424 5350.215846 3718.821391 4427.652402 3437.439253 1.048567458 0.914107465 0.833253545 0.743889666 1.268179785 2.137871504 1.556453933 1.081858069 1.288067098 1 11.7471185 -5.519853301 24.55587343 0.982147899 1.607587994 0.511332143 0.272413303 51.61083615 418895.4396 0.036039061 0.073242139 3.02E-06 5.519853301 0.625440095 LYPWGVVEVENPEHNDFLK ddPTM_HeLa_Curcumin_4h_R1 2 LYPWGVVEVENPEHNDFLK 19 0 B5MCX3;Q15019;Q15019-3;Q15019-2;H7C2Y0 B5MCX3 2-Sep Septin-2 0 0 ; ; 176.81 3.56E-07 31336000 2510.1 1680.09 2165.5 2070.34 2071.1 3699.1 2647.3 2577.4 2365.8 1928.87 FALSE FALSE TRUE 2311.422936 1825.309493 2245.755335 2061.773482 2046.403485 2931.864963 2721.576113 3363.237395 2106.277659 1995.898089 1.158086652 0.914530408 1.125185373 1.033005389 1.025304597 1.468945223 1.363584708 1.685074711 1.055303209 1 10.96282234 -5.247041804 8.771852656 1.061738833 1.492327092 0.823495267 0.09759698 0.074112906 38.87679771 0.014023593 0.034686048 5.66E-06 5.247041804 0.430588259 LYSEFLGK ddPTM_HeLa_Curcumin_4h_R1 1 LYSEFLGK 8 0 A0A3B3IU61;A0A3B3IRM5;Q5T8R1;E7EWW9;P09488-2;P46439;P09488 A0A3B3IU61 GSTM5;GSTM1 Glutathione S-transferase Mu 1;Glutathione S-transferase Mu 5 0 0 101.33 0.012204 840170 2127.2 1414.5 2094.1 1796.7 1761.2 842.98 1169.4 1732.6 1570.4 1188.6 FALSE FALSE TRUE 1958.829875 1536.763077 2171.709188 1789.265731 1740.19884 668.1364457 1202.210217 2260.861764 1398.131049 1229.903762 1.592669229 1.24949864 1.765755384 1.454801414 1.414906511 0.543242867 0.977483161 1.838242824 1.136780854 1 10.26432972 TDQEAPNASQPT(ph)PPPLPK ddPTM_HeLa_Curcumin_4h_R1 2 TDQEAPNASQPTPPPLPK 18 0 Q9H792 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 0 TDQEAPNAS(0.001)QPT(0.999)PPPLPK;TDQEAPNAS(0.005)QPT(0.995)PPPLPK ; 171 2.60E-05 16133500 9062.5 8068.4 7816 8553.1 8347.2 8882.8 5958.2 931.01 8647.4 7504.1 TRUE FALSE FALSE 8345.193562 8765.796544 8105.667836 8517.709538 8247.665092 7040.40715 6125.371056 1214.870663 7698.801855 7764.866916 1.074737488 1.12890493 1.043890117 1.096954994 1.062177263 0.906700298 0.788857185 0.156457371 0.991491797 1 12.92274548 -4.329875565 1.775591993 1.046652174 5.06E-21 0.959637536 0.05487637 0.107332687 0.373039217 0.008088616 0.17936818 4.68E-05 4.329875565 -1.046652174 down LYSILQGDS(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 2 LYSILQGDSPTK 12 0 O15042-2;O15042;O15042-3 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 1 0 LYSILQGDS(0.997)PT(0.003)K;LYSILQGDS(0.65)PT(0.35)K ; 162.67 0.00015275 42556000 2736.4 2200.06 2622 2189.07 2724.1 3215.5 2872.6 2676.5 2230.1 2356.3 TRUE FALSE FALSE 2519.811053 2390.223383 2719.173627 2180.012208 2691.616887 2548.569054 2953.197425 3492.552529 1985.463609 2438.18125 1.033479793 0.980330475 1.115246714 0.89411409 1.103944544 1.045274651 1.211229651 1.432441714 0.814321581 1 11.25158966 -4.242943603 1.259976638 1.015601072 1.640433142 0.719915484 0.086187794 0.372594817 0.478644169 0.007524757 0.304044712 5.72E-05 4.242943603 0.62483207 LYSILQGDS(ph)PTKWR ddPTM_HeLa_Curcumin_4h_R1 1 LYSILQGDSPTKWR 14 1 O15042-2;O15042;O15042-3 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 1 0 LY(0.003)S(0.006)ILQGDS(0.512)PT(0.478)KWR 64.89 0.017962 36563000 1126 1009 1030.1 1084 1203 1584.8 1238.2 1273.5 1292.7 1099 TRUE FALSE FALSE 1036.875912 1096.213464 1068.276412 1079.514695 1188.655011 1256.094616 1272.94056 1661.784288 1150.894044 1137.190168 0.911787616 0.963966709 0.939399972 0.949282473 1.045256144 1.104559862 1.119373518 1.461307294 1.012050646 1 10.15125782 -1 0.658836013 0.955904271 48.25300977 0.930469202 0.039972861 38.55123179 0.223381419 0.007300036 2669.867886 0.1 1 47.2971055 LYSILQGDSPT(ph)KWR ddPTM_HeLa_Curcumin_4h_R1 1 LYSILQGDSPTKWR 14 1 O15042-2;O15042;O15042-3 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 1 0 LYSILQGDS(0.015)PT(0.984)KWR 82.942 0.01344 38256000 1275 1297.3 1241.4 1420 1747.5 2135 1361.5 1352.8 1650.8 1629.6 TRUE FALSE FALSE 1174.082405 1409.432831 1287.407376 1414.124416 1726.662204 1692.176934 1399.700026 1765.262492 1469.71137 1686.228479 0.696277177 0.835849263 0.763483355 0.838631558 1.023978794 1.003527668 0.830077325 1.046870288 0.871596814 1 10.71958431 -5.777469595 24.17022125 0.842629445 0.967640507 0.364239181 0.091111216 208.0666942 313721.1855 0.01861088 0.033821586 1.67E-06 5.777469595 0.125011062 LYSLLGIDLTAPSNNSSPRDS(ph)PCKENK ddPTM_HeLa_Curcumin_4h_R1 2 LYSLLGIDLTAPSNNSSPRDSPCKENK 27 2 A3KN83-4;A3KN83-3;A3KN83-2;A3KN83 A3KN83-4 SBNO1 Protein strawberry notch homolog 1 1 0 LYSLLGIDLTAPS(0.045)NNS(0.045)S(0.142)PRDS(0.767)PCKENK;LYSLLGIDLTAPS(0.069)NNS(0.015)S(0.069)PRDS(0.846)PCKENK ; 118.76 2.49E-09 26719000 4597.8 3719.9 4114.8 3796.9 3552.1 4574.1 2565.2 3580.2 4946.6 3072.7 TRUE FALSE FALSE 4233.879278 4041.43158 4267.298108 3781.189434 3509.743527 3625.380099 2637.172608 4671.786499 4403.970356 3179.476096 1.331627963 1.271099847 1.342138761 1.189249209 1.103874796 1.14024449 0.829436212 1.469357327 1.385124537 1 11.63457335 -3.944968668 19.48849842 1.160368206 5.12092538 0.219457818 0.162730413 206.3424126 79032.79549 0.023034602 2757.523361 0.000113509 3.944968668 3.960557173 MAAAGGTVSGPS(ph)SACKPGR ddPTM_HeLa_Curcumin_4h_R1 1 MAAAGGTVSGPSSACKPGR 19 1 A0A087X2H1;Q9ULT8;A0A087WVU6;G3V4V5 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 0 MAAAGGTVSGPS(0.826)S(0.173)ACKPGR 127.1 5.88E-05 21698000 1179.5 689.14 1081.3 1277.7 1270.4 1899.6 1269.5 589.84 1335.5 1268.3 TRUE FALSE FALSE 1086.14133 748.7061909 1121.373929 1272.413216 1255.25131 1505.601547 1305.118753 769.6795007 1188.998991 1312.373331 0.827616125 0.570497871 0.854462601 0.96955126 0.95647426 1.147235708 0.99447217 0.586479078 0.905991431 1 10.35796247 -4.252341789 23.73114374 0.914556559 0.586478724 0.323172928 0.142206845 602.1021736 1570517.557 0.02148647 0.339118308 5.59E-05 4.252341789 -0.328077835 MAAAGGTVSGPSS(ph)ACKPGR ddPTM_HeLa_Curcumin_4h_R1 1 MAAAGGTVSGPSSACKPGR 19 1 A0A087X2H1;Q9ULT8;A0A087WVU6;G3V4V5 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 0 MAAAGGTVSGPS(0.402)S(0.597)ACKPGR 119.87 0.00010375 19218000 1481.8 1158.6 1289.3 1254.6 1476.9 2041.4 1420.4 583.43 1605.6 1289.7 TRUE FALSE FALSE 1364.513966 1258.744221 1337.082592 1249.408798 1459.288932 1617.990629 1460.252601 761.3151212 1429.469697 1334.516979 1.022477786 0.943220837 1.001922503 0.936225479 1.093495965 1.212416668 1.094218076 0.570479906 1.071151375 1 10.38210195 -4.256005118 24.97302066 1.023939671 0.570479712 0.758273549 0.079245807 229.4903256 1054584.499 0.011367086 0.131440136 5.55E-05 4.256005118 -0.45345996 MAAVKAS(ph)T(ph)S(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 MAAVKASTSK 10 1 H7BYE2;Q9NWZ8 H7BYE2 GEMIN8 Gem-associated protein 8 3 0 MAAVKAS(1)T(1)S(1)K 57.174 0.017408 3749300 1419.1 1138.1 1362.8 1327.4 1173.8 1758.8 1421.8 1374.7 1386.6 1308.6 TRUE FALSE FALSE 1306.776738 1236.472293 1413.306567 1321.907571 1159.803202 1394.005054 1461.691881 1793.839702 1234.493449 1354.073753 0.965070577 0.913149886 1.043744157 0.976244882 0.856528826 1.029489754 1.079477302 1.324772523 0.911688486 1 10.40309061 -4.240991149 1.742383466 0.974590224 1.455227738 0.807637567 0.053945659 0.29182182 0.828254457 0.007084169 0.235570205 5.74E-05 4.240991149 0.480637514 MAEAPASPAPLS(ph)PLEVELDPEFEPQSRPR ddPTM_HeLa_Curcumin_4h_R1 1 MAEAPASPAPLSPLEVELDPEFEPQSRPR 29 1 O43524;A0A2Z4LIS9 O43524 FOXO3 Forkhead box protein O3 1 0 MAEAPAS(0.088)PAPLS(0.912)PLEVELDPEFEPQSRPR 61.417 0.0042011 4017000 487.93 364.99 266.48 598.91 393.59 621.77 477.4 282.99 656.52 489.69 TRUE FALSE FALSE 449.3098256 396.5381092 276.3559832 596.4318691 388.8966963 492.8078932 490.7945591 369.2723483 584.5013985 506.7066911 0.886725661 0.782579185 0.545396357 1.177075179 0.76749864 0.972570329 0.968596957 0.728769434 1.153530058 1 8.98500707 -8.570824629 1.030989972 0.986140873 0.859186826 0.178567199 0.168970137 0.816452123 1.761022688 0.054867232 0.030599723 2.69E-09 8.570824629 -0.126954046 MAEESSSSSSSS(ph)SPTAATSQQQQLK ddPTM_HeLa_Curcumin_4h_R1 1 MAEESSSSSSSSSPTAATSQQQQLK 25 0 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 0 MAEES(0.009)S(0.009)S(0.008)S(0.008)S(0.007)S(0.006)S(0.036)S(0.44)S(0.44)PT(0.036)AATSQQQQLK 101.08 1.95E-06 22579000 1942 1597.6 1702.5 2044 1611.7 2270.6 2064.2 2082.8 2098.7 1799.6 TRUE FALSE FALSE 1788.288651 1735.689425 1765.596148 2035.54247 1592.48153 1799.651965 2122.115896 2717.836132 1868.477861 1862.135966 0.960342684 0.932095968 0.948156407 1.093122364 0.855190791 0.966444985 1.139613828 1.459526147 1.00340571 1 10.8627427 -4.341543936 2.264804961 0.973237402 1.535535536 0.870363571 0.05777635 0.118272297 0.794975337 0.007727411 0.122767503 4.55E-05 4.341543936 0.562298134 MAEESSSSSSSSS(ph)PTAATSQQQQLK ddPTM_HeLa_Curcumin_4h_R1 2 MAEESSSSSSSSSPTAATSQQQQLK 25 0 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 0 MAEESSSSSS(0.001)S(0.012)S(0.192)S(0.7)PT(0.094)AAT(0.001)SQQQQLK;MAEESSSSS(0.001)S(0.009)S(0.062)S(0.284)S(0.554)PT(0.086)AAT(0.001)SQQQQLK ; 149.16 1.87E-08 20289200 3516.8 3251 3564.3 3288.6 3297.9 4397.8 3531.6 4207 4341.6 3103.7 TRUE FALSE FALSE 3238.441569 3532.001954 3696.396093 3274.992645 3258.574696 3485.646707 3630.687191 5489.694933 3865.337342 3211.553344 1.008372343 1.099779943 1.1509683 1.019753463 1.014641311 1.085346041 1.130508138 1.709358166 1.203572517 1 11.64905554 -4.121813391 1.976178904 1.026443915 2.107486269 0.85703613 0.075628257 0.222837122 0.668112095 0.008142941 0.492657375 7.55E-05 4.121813391 1.081042354 MAFK(ac)EPKPMSK ddPTM_HeLa_Curcumin_4h_R1 2 MAFKEPKPMSK 11 2 P42568-2;P42568 P42568-2 MLLT3 Protein AF-9 0 1 ; MAFK(1)EPKPMSK;MAFK(0.974)EPK(0.026)PMSK 108.98 0.0011059 29807000 6443.2 4664.2 5701.4 6548.1 6056.1 7408.1 7092.4 5687.8 7685 7342.9 FALSE TRUE FALSE 5933.213921 5067.352665 5912.698899 6521.005697 5983.884963 5871.576554 7291.393656 7421.984037 6841.974727 7598.065228 0.780884836 0.666926713 0.778184804 0.858245553 0.787553776 0.772772591 0.959638202 0.976825522 0.900489075 1 12.89141638 -9.273464161 1.067343493 0.997242149 0.817830192 0.210569545 0.091692923 0.452556715 0.944710586 0.058618658 0.016897003 5.33E-10 9.273464161 -0.179411957 MAFYS(ph)YNSVLAIAR ddPTM_HeLa_Curcumin_4h_R1 2 MAFYSYNSVLAIAR 14 0 E9PIC7;E9PN52;E5RK40;A8K1M9;E9PMA4;Q2VYF4 E9PIC7 LETM2 "LETM1 domain-containing protein LETM2, mitochondrial" 1 0 MAFY(0.29)S(0.419)Y(0.29)NSVLAIAR;MAFY(0.274)S(0.452)Y(0.274)NSVLAIAR ; 112.71 0.0029848 8698400 168.53 188.519 223.59 0 182.14 247.41 214.344 281.22 318.24 114.962 TRUE FALSE FALSE 155.1906727 204.8137423 231.8764421 0 179.9680995 196.0943771 220.3579158 366.9626834 283.3298682 118.9569209 1.304595575 1.721747173 1.949247175 0 1.512884648 1.648448662 1.852417783 3.084836767 2.38178549 1 6.8942954 -3.902589352 1.020769662 1.190772747 5.433372181 0.351827292 0.624288783 1.865650951 0.926153222 0.074307214 10.26646718 0.000125144 3.902589352 4.242599434 MAHSKT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 MAHSKTR 7 1 Q9NTI5-2;Q9NTI5;Q9NTI5-4;Q9NTI5-3 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 MAHS(0.007)KT(0.993)R 53.493 0.0089242 0 488.2 301.55 612.39 436.38 463.07 592.27 418.07 356 556.9 499.21 TRUE FALSE FALSE 449.5584549 327.6146383 635.0857121 434.5743752 457.5481927 469.4265257 429.799919 464.5427612 495.8094633 516.5575103 0.870297006 0.634226842 1.2294579 0.841289433 0.885764283 0.908759463 0.832046598 0.899305018 0.959834004 1 9.012785169 -9.219475545 1.062904071 0.997307361 0.888110494 0.064837874 0.137310126 0.990565098 2.080017592 0.076072972 0.023401713 6.03E-10 9.219475545 -0.109196867 MALIGLGVSHPVLK ddPTM_HeLa_Curcumin_4h_R1 1 MALIGLGVSHPVLK 14 0 H3BSJ9;H3BRG4;P22695 H3BSJ9 UQCRC2 "Cytochrome b-c1 complex subunit 2, mitochondrial" 0 0 105.65 0.0021279 0 405.98 200.22 218.43 252.35 327.94 1155.3 524.25 619.75 189.97 219.89 FALSE FALSE TRUE 373.8462546 217.5261246 226.525208 251.3058426 324.0295297 915.6777571 538.9590441 808.708922 169.1307663 227.5311611 1.643055187 0.956027841 0.995578833 1.104489782 1.424110562 4.024405943 2.368726294 3.554277656 0.743330124 1 7.82992033 -5.338056214 6.901370679 1.24709349 3.216441849 0.822777015 0.46328795 0.074665159 5.737289003 0.061886842 0.139447565 4.59E-06 5.338056214 1.969348359 MALIQMGSVEEAVQALIDLHNHDLGENHHLR ddPTM_HeLa_Curcumin_4h_R1 2 MALIQMGSVEEAVQALIDLHNHDLGENHHLR 31 0 A0A0U1RRM4;A0A0D9SF20;A6NLN1;P26599;P26599-2;P26599-3 A0A0U1RRM4;A6NLN1 PTBP1 Polypyrimidine tract-binding protein 1 0 0 ; ; 106.62 9.00E-10 17970700 3101.89 2445.7 3135.39 2607.15 3099.19 7179.8 5839.6 5383.3 3828.8 4102.1 FALSE FALSE TRUE 2856.372133 2657.09541 3251.590312 2596.362304 3062.234183 5690.628547 6003.44346 7024.643388 3408.790219 4244.64767 0.672935036 0.625987271 0.766044809 0.611679109 0.721434244 1.340659812 1.414356132 1.654941455 0.803079663 1 12.05142909 -5.130633689 3.277022735 0.793833084 1.514665517 0.873888115 0.126571461 0.088190145 1.761938917 0.024376249 0.070281628 7.40E-06 5.130633689 0.720832433 MALPPQEDAT(ph)ASPPR ddPTM_HeLa_Curcumin_4h_R1 2 MALPPQEDATASPPR 15 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 MALPPQEDAT(0.645)AS(0.355)PPR;MALPPQEDAT(0.5)AS(0.5)PPR ; 91.789 0.0032282 0 3029.9 2832.6 2879.8 3392.6 3371.8 3691.6 3399.3 2791.8 3626.3 2796.2 TRUE FALSE FALSE 2790.080218 3077.437322 2986.527921 3378.56232 3331.593487 2925.920547 3494.675209 3643.006968 3228.503963 2893.367742 0.964301972 1.063617762 1.032197836 1.167691984 1.15145871 1.011250836 1.20782269 1.259088817 1.115829114 1 11.49853398 -2.942309023 0.27466294 0.971657935 1.765052573 0.390591816 0.072627528 7.737487426 0.247847618 0.03028554 2.37335458 0.001142065 2.942309023 0.793394637 MALPPQEDATAS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 12 MALPPQEDATASPPR 15 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 MALPPQEDAT(0.143)AS(0.857)PPR;MALPPQEDAT(0.008)AS(0.992)PPR;MALPPQEDAT(0.028)AS(0.972)PPR;MALPPQEDAT(0.251)AS(0.749)PPR;MALPPQEDAT(0.18)AS(0.82)PPR;MALPPQEDAT(0.285)AS(0.715)PPR;MALPPQEDAT(0.405)AS(0.595)PPR;MALPPQEDATAS(1)PPR;MALPPQEDAT(0.134)AS(0.866)PPR;MALPPQEDATAS(1)PPR;MALPPQEDAT(0.005)AS(0.995)PPR;MALPPQEDAT(0.085)AS(0.915)PPR ;;;;;;;;;;; 257.46 2.97E-39 1009436500 59109 52781.3 57290.87 53602.77 62851.6 68764.7 57211 47402.62 52453.56 47618.32 TRUE FALSE FALSE 54430.46028 57343.48038 59414.12004 53380.97594 62102.13572 54502.12608 58816.18668 61855.46062 46699.5357 49273.05308 1.104669934 1.163789877 1.205813651 1.083370577 1.260367114 1.106124396 1.193678553 1.255360826 0.947770288 1 15.58851125 -8.348445743 0.254151846 0.936581213 1.226264601 0.693218807 0.054580234 1.260876062 0.200803325 0.132499047 0.057435236 4.48E-09 8.348445743 0.289683389 MALPPQEDATAS(ph)PPRQK ddPTM_HeLa_Curcumin_4h_R1 3 MALPPQEDATASPPRQK 17 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 MALPPQEDAT(0.12)AS(0.88)PPRQK;MALPPQEDAT(0.169)AS(0.831)PPRQK;MALPPQEDAT(0.001)AS(0.999)PPRQK ;; 195.6 1.98E-07 192610000 12793.2 9129.9 9330.1 10183.1 8371.1 12474.5 9217.1 8273.8 13028 11325 TRUE FALSE FALSE 11780.60472 9919.047874 9675.881714 10140.96503 8271.2801 9887.148083 9475.707019 10796.44353 11598.86099 11718.54291 1.005296035 0.846440377 0.825689831 0.865377642 0.705828375 0.843718213 0.808607955 0.921312796 0.989786963 1 13.51650557 -7.22576274 4.374259971 1.002924106 0.825390804 0.69332328 0.051021236 0.076645328 3.425609424 0.008179363 0.009879875 5.95E-08 7.22576274 -0.177533303 MANS(ph)SPVLSK ddPTM_HeLa_Curcumin_4h_R1 1 MANSSPVLSK 10 0 Q9NXE8 Q9NXE8 CWC25 Pre-mRNA-splicing factor CWC25 homolog 1 0 MANS(0.692)S(0.295)PVLS(0.012)K 94.82 0.018675 11753000 5668.7 5077.9 5198.2 5849.2 5455.7 6971.6 5782.6 3282.2 5618.7 5143.2 TRUE FALSE FALSE 5220.016413 5516.811049 5390.849865 5824.99756 5390.644341 5525.611574 5944.844193 4282.927671 5002.342667 5321.925817 0.980851029 1.036619306 1.01295096 1.094528139 1.012912341 1.038272942 1.11704755 0.804770269 0.939949717 1 12.37773269 -4.242258571 24.80051556 1.013126598 0.804770061 0.628188028 0.050178659 2100.525108 2715904.447 0.0066492 0.336486776 5.72E-05 4.242258571 -0.208356536 MANSS(ph)PVLSK ddPTM_HeLa_Curcumin_4h_R1 1 MANSSPVLSK 10 0 Q9NXE8 Q9NXE8 CWC25 Pre-mRNA-splicing factor CWC25 homolog 1 0 MANS(0.085)S(0.915)PVLS(0.001)K 155.47 0.0006407 74027000 5996.3 4861.1 5708.4 5737.3 5995.6 7104 5991.3 3225.7 6281.3 5092.7 TRUE FALSE FALSE 5521.686528 5281.271823 5919.958326 5713.560573 5924.106386 5630.550321 6159.399753 4209.201081 5592.257105 5269.670946 1.04782378 1.002201442 1.123401895 1.08423479 1.124189052 1.068482336 1.168839538 0.798759756 1.061215617 1 12.36349716 -8.35189223 0.685998237 1.003909711 1.064005511 0 0.097797863 1.519233725 1.529294568 0.042332918 0.021849707 4.45E-09 8.35189223 0.0600958 MAPALSGANLT(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 MAPALSGANLTSPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 MAPALSGANLT(0.865)S(0.135)PR 147.7 0.0016565 73568000 1820.7 1627.9 1394.2 1415.2 1793.5 2112.5 1826.5 1898.9 1592 1745.4 TRUE FALSE FALSE 1676.589674 1768.608422 1445.870278 1409.344277 1772.113684 1674.343687 1877.746674 2477.865869 1417.361583 1806.05252 0.928317231 0.979267437 0.800569342 0.780345124 0.981208278 0.927073642 1.039696605 1.371978855 0.784784256 1 10.81862413 -4.25735078 2.378546078 0.940193753 1.477390094 0.715248041 0.087516715 0.232080886 1.546052386 0.011414505 0.256865399 5.53E-05 4.25735078 0.537196341 MAPALSGANLTS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 MAPALSGANLTSPR 14 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 MAPALSGANLT(0.023)S(0.977)PR 161.04 0.00027974 85812000 1428.2 1290.3 1511.4 1251.4 1530.3 1846.1 1520.8 1560.7 1433.8 1386.3 TRUE FALSE FALSE 1315.156463 1401.827783 1567.413814 1246.222038 1512.052172 1463.19805 1563.469555 2036.550245 1276.515727 1434.473822 0.916821515 0.977241802 1.092675091 0.868765968 1.054081398 1.020024226 1.08992547 1.419719352 0.889884296 1 10.48630592 MAPPVDDLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 MAPPVDDLSPK 11 0 E7ER40;E7EVH3;Q92576-2;Q92576 E7ER40 PHF3 PHD finger protein 3 1 0 MAPPVDDLS(1)PK;MAPPVDDLS(1)PK;MAPPVDDLS(1)PK;MAPPVDDLS(1)PK ;;; 117.03 0.0053477 346677000 18370.1 16139 17755.1 17598.7 16956 19644.5 17089.6 13701.4 20757.5 17824.8 TRUE FALSE FALSE 16916.0872 17533.98325 18413.11962 17525.88124 16753.81077 15570.00926 17569.08818 17878.89379 18480.45418 18444.21047 0.917148892 0.950649705 0.99831433 0.950210434 0.908350661 0.844167837 0.952553009 0.969349911 1.001965045 1 14.17088041 -5.869182769 5.105317396 0.961968343 0.915912719 0.27326293 0.039917087 0.275449617 11.35993529 0.006686588 0.012353003 1.35E-06 5.869182769 -0.046055625 MAPT(ph)PIPT(ph)RSPSDSSTASTPVAEQIER ddPTM_HeLa_Curcumin_4h_R1 2 MAPTPIPTRSPSDSSTASTPVAEQIER 27 1 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 2 0 MAPT(0.99)PIPT(0.427)RS(0.425)PS(0.143)DS(0.007)S(0.003)T(0.003)AS(0.001)T(0.001)PVAEQIER;MAPT(1)PIPT(0.979)RS(0.02)PSDS(0.001)STASTPVAEQIER ; 90.545 4.24E-06 43174000 3504.7 2438.3 2514.6 2794.6 2296.65 1822.19 1502.59 1105.92 3070 2475 TRUE FALSE FALSE 3227.299297 2649.055787 2607.793288 2783.036686 2269.263949 1444.247254 1544.748631 1443.109917 2733.228681 2561.006066 1.260168549 1.034380911 1.018269079 1.08669664 0.886083004 0.563937459 0.603180388 0.563493362 1.067248031 1 11.32249495 -5.476617997 2.063103106 1.109825037 0.568146215 0.900779851 0.073762597 0.092899914 0.775864563 0.015726065 0.041178333 3.34E-06 5.476617997 -0.541678822 MAPT(ph)PIPTR ddPTM_HeLa_Curcumin_4h_R1 1 MAPTPIPTR 9 0 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 0 MAPT(1)PIPTR 121.29 0.017109 48286000 2723.7 2154 2331.5 2252.5 2119.4 2223.5 1824.5 703.5 2639.8 1721.6 TRUE FALSE FALSE 2508.116271 2340.182162 2417.907441 2243.179752 2094.127539 1762.321036 1875.69056 917.9939115 2350.220544 1781.425472 1.407926579 1.313657068 1.357288014 1.259204939 1.175534746 0.989275759 1.052915538 0.515314239 1.319292096 1 10.79881641 -4.056747065 1.077976926 1.220824509 1.60E-16 0.752236333 0.125618573 1.362693773 0.940934916 0.025956378 2.099250799 8.78E-05 4.056747065 -1.220824509 MAPTPIPT(ph)RSPSDSSTASTPVAEQIER ddPTM_HeLa_Curcumin_4h_R1 4 MAPTPIPTRSPSDSSTASTPVAEQIER 27 1 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 0 MAPT(0.004)PIPT(0.469)RS(0.469)PS(0.039)DS(0.004)S(0.005)T(0.005)AS(0.002)T(0.002)PVAEQIER;MAPT(0.002)PIPT(0.497)RS(0.497)PS(0.003)DSSTASTPVAEQIER;MAPT(0.011)PIPT(0.381)RS(0.381)PS(0.14)DS(0.021)S(0.025)T(0.025)AS(0.012)T(0.005)PVAEQIER;MAPT(0.002)PIPT(0.933)RS(0.057)PS(0.007)DSSTASTPVAEQIER ;;; 125.79 1.17E-08 903215000 5228.93 4318.22 4305.23 4505.53 4430.48 4639.65 2114.94 2503.83 4915.23 4287.68 TRUE FALSE FALSE 4815.054673 4691.467695 4464.785611 4486.887311 4377.64942 3677.33429 2174.279524 3267.236241 4376.041566 4436.676561 1.085284133 1.057428377 1.00633561 1.011317199 0.98669564 0.828848856 0.490069423 0.736415241 0.98633324 1 12.11526367 -5.074597136 2.603240304 1.035812827 0.613337162 0.85142699 0.067215301 0.064393906 0.846405537 0.00901335 0.029481134 8.42E-06 5.074597136 -0.422475665 MAPTPIPTRS(ph)PS(ph)DSSTASTPVAEQIER ddPTM_HeLa_Curcumin_4h_R1 1 MAPTPIPTRSPSDSSTASTPVAEQIER 27 1 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 2 0 MAPT(0.077)PIPT(0.342)RS(0.571)PS(0.287)DS(0.241)S(0.072)T(0.104)AS(0.16)T(0.146)PVAEQIER 47.854 0.018791 13215000 1381.5 867.05 824.01 1099.1 1367.2 1838.4 1732.7 1051.6 1234.9 1311.9 TRUE FALSE FALSE 1272.152817 941.9939385 854.5485355 1094.552215 1350.897033 1457.095117 1781.314899 1372.227999 1099.43456 1357.488427 0.937137136 0.693924102 0.62950705 0.806306848 0.995144419 1.073375719 1.31221369 1.010857972 0.809903449 1 10.40672418 -5.261855209 2.743398273 0.908512127 1.162809763 0.429277337 0.142945612 0.257634833 3.837962367 0.023400507 0.064620894 5.47E-06 5.261855209 0.254297636 MAS(ph)NIFGTPEENQASWAK ddPTM_HeLa_Curcumin_4h_R1 1 MASNIFGTPEENQASWAK 18 0 Q9UK76;J3KT51;Q9UK76-2;Q9UK76-3;J3KSH8 Q9UK76;Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 1 0 MAS(0.821)NIFGT(0.179)PEENQASWAK 68.576 0.018169 12729000 1211.2 924.89 898.88 1013.6 1249.1 2096.6 1733.6 799.4 1215.2 772.12 TRUE FALSE FALSE 1115.332242 1004.83337 932.1932835 1009.405992 1234.205298 1661.741526 1782.24015 1043.13338 1081.8956 798.9511125 1.395995605 1.257690683 1.166771369 1.263413964 1.544782001 2.079903889 2.230724912 1.305628547 1.354144932 1 9.641963418 -5.567801711 2.924167164 1.199310969 1.904177879 0.562730866 0.247578969 0.132135322 2.291415726 0.03741974 0.083975352 2.71E-06 5.567801711 0.70486691 MAS(ph)S(ph)AKSAEMPT(ph)IS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 MASSAKSAEMPTISK 15 1 D6RFL8;Q9BXG8 D6RFL8 SPZ1 Spermatogenic leucine zipper protein 1 4 0 MAS(0.969)S(0.975)AKS(0.056)AEMPT(1)IS(1)K 63.918 0.0075479 0 511.73 518.44 570.65 642.03 612.89 372.56 417.09 327.88 570.56 541.76 TRUE FALSE FALSE 471.2260305 563.2516435 591.798791 639.37345 605.581687 295.2868564 428.7924229 427.8491026 507.9709955 560.5861197 0.840595252 1.004754887 1.055678637 1.140544561 1.080265218 0.526746643 0.764900178 0.763217439 0.906142656 1 9.130792213 -5.268014019 24.99513977 0.964911972 0.692949294 0.644590499 0.105762366 312.9831562 1189885.344 0.017655517 0.040362675 5.39E-06 5.268014019 -0.271962678 MAS(ph)VNMDPALMFRTRK ddPTM_HeLa_Curcumin_4h_R1 1 MASVNMDPALMFRTRK 16 2 A0A2R8YGD3;Q9Y4G8 A0A2R8YGD3 RAPGEF2 Rap guanine nucleotide exchange factor 2 1 0 MAS(1)VNMDPALMFRTRK 49.5 0.017878 79271000 1235.1 1248.6 1077.2 1117.1 1137.5 1360.1 1355.4 882.47 1227.8 984.69 TRUE FALSE FALSE 1137.340532 1356.52342 1117.12198 1112.477736 1123.936055 1077.999929 1393.428876 1151.531041 1093.113412 1018.907904 1.11623487 1.331350375 1.096391514 1.091833454 1.103079141 1.057995452 1.367570975 1.130162045 1.072828474 1 9.992807942 -8.428509963 0.880350253 1.01242632 1.163860524 0.188512701 0.100868663 0.506205299 0.815612619 0.0375805 0.021262821 3.73E-09 8.428509963 0.151434205 MASNIFGT(ph)PEENQASWAK ddPTM_HeLa_Curcumin_4h_R1 1 MASNIFGTPEENQASWAK 18 0 Q9UK76;J3KT51;Q9UK76-2;Q9UK76-3;J3KSH8 Q9UK76;Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 1 0 MAS(0.002)NIFGT(0.998)PEENQASWAK 160.64 0.00086891 71753000 2622.1 1705.6 2226.8 2535.6 2171 4359.1 4257.1 1794.6 2602.8 1565.1 TRUE FALSE FALSE 2414.558018 1853.024464 2309.327167 2525.108359 2145.112243 3454.973523 4376.542769 2341.765279 2317.279352 1619.487109 1.490939944 1.144204517 1.425962056 1.559202507 1.324562716 2.133375131 2.702425197 1.445991923 1.430872367 1 10.66132127 -5.268342611 5.268778854 1.273824658 2.161069798 0.518473119 0.327534406 0.090053059 8.512237144 0.046981057 0.113812736 5.39E-06 5.268342611 0.88724514 MASSGMT(ph)RR ddPTM_HeLa_Curcumin_4h_R1 1 MASSGMTRR 9 1 F5GWZ1;Q9BTZ2-3;Q9BTZ2-7;Q9BTZ2-2;Q9BTZ2-5;Q9BTZ2-8;Q9BTZ2-4;Q9BTZ2 F5GWZ1 DHRS4 Dehydrogenase/reductase SDR family member 4 1 0 MASS(0.002)GMT(0.998)RR 47.894 0.01995 19113000 59.475 144.49 140.8 111.63 249.36 206.68 0 169.13 157.04 0 TRUE FALSE FALSE 54.76749099 156.9790718 146.0181719 111.1681046 246.3865449 163.8122382 0 220.6969584 139.8131049 0 0 ATGAALT(ph)PTEER ddPTM_HeLa_Curcumin_4h_R1 4 ATGAALTPTEER 12 0 M0R0P8;Q13459-2;Q13459;M0R300 M0R0P8 MYO9B Unconventional myosin-IXb 1 0 ATGAALT(0.918)PT(0.082)EER;ATGAALT(0.929)PT(0.071)EER;ATGAALT(0.936)PT(0.064)EER;ATGAALT(0.992)PT(0.007)EER ;;; 156.81 0.00088471 62678200 10757.9 10305.4 10714.3 11692.9 10317.3 13367.1 12717.6 25981.2 11664.5 9935 TRUE FALSE FALSE 9906.400863 11196.15286 11111.38138 11644.51788 10194.27294 10594.61278 13074.42163 33902.74828 10384.93353 10280.24051 0.963635126 1.089094447 1.080848388 1.132708701 0.991637591 1.030580245 1.271801143 3.297855555 1.010183908 1 13.3275864 -4.252186952 3.31559465 1.012638132 3.633328443 0.993589301 0.054101686 0.021730348 0.380014927 0.009381234 0.146383869 5.60E-05 4.252186952 2.620690311 up MS(ph)TRNASPCMT(ph)S(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 MSTRNASPCMTSSR 14 1 H3BM29 H3BM29 CALML4 3 0 MS(0.785)T(0.222)RNAS(0.23)PCMT(0.588)S(0.686)S(0.49)R 51.466 0.018731 5304000 1632.1 1648.5 1208.6 1414.7 1396.1 2307.5 1245.6 477.74 1693.1 1505.7 TRUE FALSE FALSE 1502.917563 1790.988994 1253.391779 1408.846346 1379.452419 1828.898489 1280.548184 623.4007268 1507.371166 1558.022963 0.964631202 1.1495267 0.804475806 0.90425262 0.885386449 1.173858494 0.821905847 0.400122939 0.967489698 1 10.60550078 -4.329158132 3.312032883 0.980099175 0.360577917 0.724472109 0.107678096 0.098468097 1.751625953 0.013872313 0.138684073 4.69E-05 4.329158132 -0.619521258 down MDAEVPDVNIEGPDAK ddPTM_HeLa_Curcumin_4h_R1 1 MDAEVPDVNIEGPDAK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 101.89 0.012654 4354000 738.81 655.99 849.9 798.1 875.13 778.66 837.54 728.77 800.38 776.55 FALSE FALSE TRUE 680.3324089 712.6908526 881.3980416 794.7976737 864.6946463 617.1571387 861.0391183 950.9686182 712.5803165 803.5350547 0.846674212 0.88694432 1.096900548 0.989126323 1.076113159 0.768052539 1.071563852 1.183481184 0.886806758 1 9.650217153 -6.776590529 24.9985516 0.922524217 1.020934951 0.235978809 0.108193662 352.092157 580930.938 0.018513694 0.024381529 1.67E-07 6.776590529 0.098410734 MDCQECPEGYR ddPTM_HeLa_Curcumin_4h_R1 3 MDCQECPEGYR 11 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ;; ;; 138.76 0.00016889 187071300 3439.4 2527.8 3013.89 2935.17 3507.1 4172.2 2898.15 2769.51 2925.12 2638.05 FALSE FALSE TRUE 3167.167861 2746.291768 3125.587415 2923.025044 3465.280123 3306.83869 2979.464289 3613.92085 2604.241654 2729.722041 1.16025288 1.006070115 1.145020397 1.070814171 1.269462631 1.211419566 1.091489992 1.323915327 0.954031808 1 11.41453834 -1.000000359 0.020749573 2.23E-08 2.629328235 0.526163187 0.079258815 1747.004169 2.821417687 131.6335812 241.6431418 0.099999917 1.000000359 2.629328213 RNS(ph)SEASS(ph)GDFLDLK ddPTM_HeLa_Curcumin_4h_R1 1 RNSSEASSGDFLDLK 15 1 Q9UK76;J3KT51;Q9UK76-2;Q9UK76-3;J3KSH8 Q9UK76;Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 2 0 RNS(0.953)S(0.048)EAS(0.29)S(0.709)GDFLDLK 99.313 0.001718 2725300 1857.8 1622 2013.9 2070.2 2018.1 2299.8 2595.2 8494.1 1593.9 1313.4 TRUE FALSE FALSE 1710.75317 1762.198453 2088.536906 2061.634061 1994.035476 1822.795556 2668.014327 11083.91199 1419.053158 1359.040552 1.258794792 1.296648911 1.536773058 1.516977589 1.467237657 1.341237061 1.963160204 8.15568893 1.044158068 1 10.40837279 -4.252184291 3.410610982 1.236785648 9.117465291 0.991938711 0.183967832 0.024567764 0.470101644 0.03357413 0.506989592 5.60E-05 4.252184291 7.880679644 up MDGEATS(ph)PLPR ddPTM_HeLa_Curcumin_4h_R1 2 MDGEATSPLPR 11 0 Q86UU1-3;Q86UU1-2;Q86UU1;A0A087WZL0 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 0 MDGEAT(0.042)S(0.958)PLPR;MDGEAT(0.032)S(0.968)PLPR ; 116.84 0.0046111 26980000 10377.1 9593.5 9997.4 10617.9 10802.7 8792.2 7494.4 3717.2 9258 8187.9 TRUE FALSE FALSE 9555.741585 10422.71939 10367.91244 10573.96594 10673.88486 6968.598611 7704.672694 4850.557168 8242.420562 8472.428916 1.127863294 1.230192604 1.223723745 1.248044221 1.259837641 0.822503049 0.909381804 0.572510813 0.972852135 1 13.04855991 -4.543031204 1.365140012 1.109356422 0.531936424 0.664740837 0.123937776 0.419003114 0.976051551 0.019770957 0.287568029 2.86E-05 4.543031204 -0.577419999 MDIDAPDVDVHGPDWHLK ddPTM_HeLa_Curcumin_4h_R1 2 MDIDAPDVDVHGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 97.129 0.00064378 38117000 10224.6 8536.7 9225.8 9913.4 10296.3 12859.9 8711.3 8889.7 11770.8 9641.7 FALSE FALSE TRUE 9415.312121 9274.574309 9567.716264 9872.380978 10173.52335 10192.61178 8955.715633 11600.12861 10479.57269 9976.748357 0.943725529 0.929618948 0.959001462 0.989538938 1.019723359 1.021636651 0.897658767 1.162716367 1.050399621 1 13.28435397 -5.963909924 3.530837205 0.967879012 1.015884816 0.09195872 0.067509458 0.391853083 10.29873672 0.008884923 0.016405722 1.09E-06 5.963909924 0.048005804 MDIDAPDVEVQGPDWHLK ddPTM_HeLa_Curcumin_4h_R1 2 MDIDAPDVEVQGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 115.2 0.0018282 27115000 9196.7 7426.9 8328.6 8167.4 8733.3 11022.3 7769.3 7763 10154.4 7495.4 FALSE FALSE TRUE 8468.771491 8068.848142 8637.265243 8133.605463 8629.161101 8736.150733 7987.285648 10129.90296 9040.487725 7755.864592 1.09191843 1.040354437 1.11364312 1.048703902 1.112598215 1.12639289 1.029838202 1.306095902 1.165632486 1 12.9210719 MDIDVPDVEVQGPDWHLK ddPTM_HeLa_Curcumin_4h_R1 2 MDIDVPDVEVQGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 129.11 0.00017281 23999500 5697.7 4538.6 5142 6051.2 5148.7 6960.4 4943.2 5009.9 7092.1 5306.4 FALSE FALSE TRUE 5246.721033 4930.89636 5332.567043 6026.161738 5087.305115 5516.73458 5081.892888 6537.395447 6314.114374 5490.797005 0.955548171 0.898029258 0.971182697 1.09750219 0.926514878 1.004723827 0.925529187 1.190609567 1.149944966 1 12.42279986 -6.448770552 24.99971118 0.970550447 1.018004616 0 0.095783533 271.2601528 91506.02667 0.011220515 0.017139617 3.56E-07 6.448770552 0.04745417 MDKEETKDWILPSDYDHAEAEAR ddPTM_HeLa_Curcumin_4h_R1 2 MDKEETKDWILPSDYDHAEAEAR 23 2 O43852-2;O43852;O43852-4;O43852-3;H0Y875;O43852-15 O43852-2 CALU Calumenin 0 0 ; ; 61.985 0.0020939 96609000 6374.3 5176.6 5444.1 5760.3 5793 6538.4 4554.7 3391.8 6603.7 5499.2 FALSE FALSE TRUE 5869.767429 5624.042238 5645.863135 5736.465405 5723.922259 5182.262137 4682.492624 4425.944206 5879.290632 5690.296791 1.031539768 0.988356573 0.992191329 1.008113569 1.005909264 0.910719129 0.822890755 0.777805512 1.033213354 1 12.47428819 -4.895008114 1.628011624 1.011456169 0.775060005 0.970120549 0.014736262 0.053197346 0.251191984 0.00240016 0.013513632 1.27E-05 4.895008114 -0.236396164 MDLNSEQAEQLER ddPTM_HeLa_Curcumin_4h_R1 1 MDLNSEQAEQLER 13 0 Q52LJ0-1;Q52LJ0 Q52LJ0-1 FAM98B Protein FAM98B 0 0 152.7 0.0023656 14971000 926.93 1157.3 801.62 876.33 1006 1118 934.88 710.79 965.14 966.62 FALSE FALSE TRUE 853.5625124 1257.331855 831.3287424 872.7039787 994.004107 886.1141975 961.1102167 927.5065989 859.2665567 1000.209973 0.853383325 1.257067905 0.831154222 0.872520773 0.993795437 0.885928177 0.960908452 0.927311888 0.859086172 1 9.96608718 MDRT(ph)PPPPT(ph)LSPAAITVGR ddPTM_HeLa_Curcumin_4h_R1 4 MDRTPPPPTLSPAAITVGR 19 1 E7EX82;Q8NDX5-2;Q8NDX5;Q8NDX5-7;H7C4H9 E7EX82 PHC3 Polyhomeotic-like protein 3 2 0 MDRT(1)PPPPT(0.881)LS(0.118)PAAITVGR;MDRT(1)PPPPT(0.998)LS(0.002)PAAITVGR;MDRT(1)PPPPT(0.992)LS(0.008)PAAITVGR;MDRT(1)PPPPT(0.889)LS(0.11)PAAIT(0.001)VGR ;;; 132.24 5.53E-05 124807000 9684.5 8584.7 8432.7 8977.2 8322.3 7664.1 5623.5 3914.19 9380 8422 TRUE FALSE FALSE 8917.961606 9326.723215 8745.22328 8940.054725 8223.062008 6074.479268 5781.280275 5107.608512 8351.037468 8714.663873 1.023328236 1.07023327 1.003506665 1.025863402 0.943589119 0.697041143 0.663396817 0.586093576 0.95827419 1 13.0892293 -5.247285954 2.098475605 1.017132724 0.621930654 0.96537713 0.03122848 0.032678849 0.276196154 0.003811065 0.01182835 5.66E-06 5.247285954 -0.39520207 MDRT(ph)PPPPTLSPAAITVGR ddPTM_HeLa_Curcumin_4h_R1 2 MDRTPPPPTLSPAAITVGR 19 1 E7EX82;Q8NDX5-2;Q8NDX5;Q8NDX5-7;H7C4H9 E7EX82 PHC3 Polyhomeotic-like protein 3 1 0 MDRT(1)PPPPTLSPAAITVGR;MDRT(1)PPPPTLSPAAITVGR ; 109.5 0.00031322 46243000 2462.95 1993.04 1844.24 2149.67 2250.44 2487.33 2258.91 875.82 2427.7 2241.05 TRUE FALSE FALSE 2268.004909 2165.309497 1912.589157 2140.775235 2223.604973 1971.42972 2322.288935 1142.853486 2161.387384 2318.926321 0.978040953 0.933755194 0.824773577 0.923175185 0.958894189 0.850147632 1.001450074 0.492837343 0.932063845 1 11.17924127 -4.258300244 24.91814968 0.959534511 0.492837163 0.82177339 0.060501643 89.18727346 707922.7018 0.009240888 0.088218169 5.52E-05 4.258300244 -0.466697348 MDS(ph)CLMVWHMK ddPTM_HeLa_Curcumin_4h_R1 1 MDSCLMVWHMK 11 0 Q8NBT0-3 Q8NBT0-3 1 0 MDS(1)CLMVWHMK 47.574 0.018524 1648600 0 0 0 0 0 159.55 0 0 0 60.052 TRUE FALSE FALSE 0 0 0 0 0 126.4575315 0 0 0 62.13880253 0 0 0 0 0 2.035081565 0 0 0 1 5.957422535 -9.406276436 1.15108184 0.997032941 0.249239299 0 0.674609923 0.697010879 1.661857679 0.410702779 0.105987882 3.92E-10 9.406276436 -0.747793642 MDS(ph)DEDEKEGEEEK ddPTM_HeLa_Curcumin_4h_R1 4 MDSDEDEKEGEEEK 14 1 Q96ST2-3;Q96ST2;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 0 MDS(1)DEDEKEGEEEK;MDS(1)DEDEKEGEEEK;MDS(1)DEDEKEGEEEK;MDS(1)DEDEKEGEEEK ;;; 220.27 4.00E-13 188663000 14849.2 13374 15056.7 14286.4 16396.8 14562.8 14689 13953 13574.4 11419 TRUE FALSE FALSE 13673.87015 14529.98897 15614.71455 14227.28666 16201.27887 11542.31112 15101.13381 18207.20547 12085.32228 11815.8094 1.157252092 1.22970746 1.321510361 1.204089045 1.371152692 0.976853192 1.278044804 1.540919022 1.022809515 1 13.52843084 -12.33398902 0.054751502 7.63E-10 1.797160781 0.420514595 0.129465555 202.9756354 1.103249126 33.00812414 9.621349663 4.63E-13 12.33398902 1.79716078 MDS(ph)DEDEKEGEEEKVAK ddPTM_HeLa_Curcumin_4h_R1 1 MDSDEDEKEGEEEKVAK 17 2 Q96ST2-3;Q96ST2;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 0 MDS(1)DEDEKEGEEEKVAK 76.573 0.0088605 148890000 3672.5 2960.8 3388.2 3523.5 3477.5 3887 3425.4 3227.2 4532.8 3347 TRUE FALSE FALSE 3381.81775 3216.718359 3513.769673 3508.920691 3436.033084 3080.792384 3521.507505 4211.158424 4035.563181 3463.308001 0.9764704 0.92879939 1.014570368 1.013170267 0.992124605 0.88955195 1.0168046 1.215935292 1.165233695 1 11.75793498 -4.281811012 4.111424952 0.98207293 1.231416161 0.458726047 0.069000284 0.06898941 2.483925377 0.005090463 0.048786654 5.23E-05 4.281811012 0.24934323 AAAT(ph)PESQEPQAK ddPTM_HeLa_Curcumin_4h_R1 4 AAATPESQEPQAK 13 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 0 AAAT(0.995)PES(0.005)QEPQAK;AAAT(1)PESQEPQAK;AAAT(0.892)PES(0.108)QEPQAK;AAAT(1)PESQEPQAK ;;; 184.11 3.12E-07 94988000 12182.7 9516.3 9992.3 9133.9 9965 14262.5 13918.6 38011.5 10799 9360.4 TRUE FALSE FALSE 11218.42644 10338.84657 10362.62343 9096.106342 9846.173883 11304.29673 14309.11846 49601.03137 9614.376718 9685.673203 1.15824953 1.067437064 1.069891913 0.939130007 1.016570937 1.167115232 1.47734888 5.121072157 0.992638975 1 13.24163661 -4.251916889 3.453370492 1.070058933 5.67174521 0.996547927 0.071400606 0.015376905 0.306121268 0.012524497 0.186878286 5.60E-05 4.251916889 4.601686277 up TDASSAS(ph)SFLDSDELER ddPTM_HeLa_Curcumin_4h_R1 2 TDASSASSFLDSDELER 17 0 G3XAC6;Q14498-2;Q14498;H0Y4X3;Q14498-3;A0A0U1RQW2;A0A0U1RQH7 G3XAC6 RBM39 RNA-binding protein 39 1 0 TDASSAS(0.346)S(0.346)FLDS(0.308)DELER;TDASS(0.005)AS(0.827)S(0.168)FLDSDELER ; 193.64 3.24E-25 2392500 1506.46 1360.41 1158.7 1763.98 1493.94 2047.6 1828 3566.1 1759.77 1712.27 TRUE FALSE FALSE 1387.222101 1477.997779 1201.642441 1756.681118 1476.125741 1622.904679 1879.28876 4653.387474 1566.727634 1771.771255 0.782957787 0.83419221 0.678215338 0.991483022 0.833135619 0.915978671 1.060683627 2.626404205 0.884271956 1 10.79097664 -4.251904262 3.418339203 0.879874948 2.86866681 0.970731903 0.091146901 0.043686757 0.841578384 0.015097185 0.227925975 5.60E-05 4.251904262 1.988791862 up MDSNFGLAGLPGS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 MDSNFGLAGLPGSPK 15 0 O43463;O43463-2 O43463 SUV39H1 Histone-lysine N-methyltransferase SUV39H1 1 0 MDSNFGLAGLPGS(1)PK;MDSNFGLAGLPGS(1)PK ; 114.58 0.0020369 49988400 5862.2 4754.5 4443.8 5425.6 4614.5 6175.1 4278.4 2896.5 5434.7 4941.4 TRUE FALSE FALSE 5398.200684 5165.457794 4608.491137 5403.150305 4559.475101 4894.314652 4398.440389 3779.629516 4838.527007 5113.113282 1.055756129 1.010237307 0.901308241 1.056724153 0.891721902 0.957208335 0.860227448 0.739203164 0.946297635 1 12.31998627 -3.074832818 0.479047147 1.023238156 6.58E-11 0.654705591 0.054610201 4.163821232 0.275957169 0.010065376 3.112010126 0.000841719 3.074832818 -1.023238156 MDSTEPPYSQK ddPTM_HeLa_Curcumin_4h_R1 2 MDSTEPPYSQK 11 0 Q5VTE0;P68104;A0A087WV01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 0 ; ; 215.06 2.08E-30 8767100 9836.2 7467.4 8865.9 8554.1 9308.2 8435.8 6191.5 4592.1 8054 7011.9 FALSE FALSE TRUE 9057.654391 8112.848782 9194.478053 8518.705401 9197.205794 6686.119989 6365.216826 5992.210151 7170.49635 7255.563003 1.24837375 1.118155652 1.267231509 1.174092954 1.267607461 0.921516357 0.877287789 0.82587804 0.988275665 1 12.82487185 -5.108706826 5.238101489 1.144146155 0.862052834 0.645006544 0.09481987 0.124109729 4.954934233 0.015646806 0.041336388 7.79E-06 5.108706826 -0.28209332 MDSTEPPYSQK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 MDSTEPPYSQKR 12 1 Q5VTE0;P68104;A0A087WV01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 1 ; MDSTEPPYSQK(1)R;MDSTEPPYSQK(1)R 138.99 5.70E-05 3434700 840.13 992.08 700.88 803.1 968.99 1248.76 874.23 759.49 1534.64 790.74 FALSE TRUE FALSE 773.632824 1077.830975 726.8552294 799.776985 957.4354271 989.7530996 898.7585409 991.0550047 1366.293831 818.2181561 0.945509236 1.317290464 0.88833916 0.977461792 1.170146886 1.209644509 1.098433876 1.211235656 1.66984052 1 9.676341741 -5.616653685 0.501208539 0.979573319 1.221000198 0 0.247855546 1.481548733 0.544555062 0.029342172 0.168822858 2.42E-06 5.616653685 0.241426879 MDVNVGDIDIEGPEGK ddPTM_HeLa_Curcumin_4h_R1 1 MDVNVGDIDIEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 182.37 6.22E-05 5917700 1608.6 1120 1370.1 1314.2 1308.5 1485.6 1172.8 1071 1516.1 1226.3 FALSE FALSE TRUE 1481.277613 1216.807809 1420.877111 1308.762189 1292.896992 1177.469814 1205.705612 1397.54297 1349.787623 1268.913834 1.167358707 0.958936515 1.119758547 1.031403515 1.018900541 0.927935201 0.950187144 1.10136948 1.063734658 1 10.30937839 -5.846577613 2.566441444 1.072940078 0.988623512 0.136215841 0.06946383 0.372250171 4.986204812 0.012269789 0.024673918 1.42E-06 5.846577613 -0.084316566 MDYEDDRLR ddPTM_HeLa_Curcumin_4h_R1 2 MDYEDDRLR 9 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 0 ; ; 99.136 0.0072322 128070000 8850.6 7161.4 7384.4 7841.9 7251.6 8524.5 7694.6 6067 7688.8 6933.7 FALSE FALSE TRUE 8150.065671 7780.399505 7658.07236 7809.452296 7165.129406 6756.422609 7910.489767 7916.800371 6845.357876 7174.645559 1.13595377 1.084429808 1.067379886 1.088479177 0.998673641 0.941708208 1.102561751 1.103441321 0.954103979 1 12.80869185 -5.779615258 24.84273973 1.069163419 1.034530319 0 0.065093164 561.837861 767918.432 0.010039117 0.018222519 1.66E-06 5.779615258 -0.0346331 MEASALT(ph)S(ph)S(ph)AVTSVAK ddPTM_HeLa_Curcumin_4h_R1 1 MEASALTSSAVTSVAK 16 0 G3V4U3;A0A5H1ZRT4;A0A087WV79;A0A087WUJ8;A0A087X174;A0A087WZR1;P40305-1;P40305 G3V4U3 IFI27 "Interferon alpha-inducible protein 27, mitochondrial" 3 0 MEAS(0.004)ALT(0.971)S(0.977)S(0.977)AVT(0.039)S(0.032)VAK 91.441 0.016212 5106100 1072.7 908.52 1059.8 1168.6 1132 1243.3 991.26 1252.3 982.13 1091 TRUE FALSE FALSE 987.7946631 987.0484205 1099.07712 1163.764643 1118.501639 985.4255651 1019.072088 1634.120505 874.3927962 1128.912169 0.874996913 0.874335885 0.97357186 1.030872618 0.990778264 0.872898346 0.902702722 1.447517841 0.774544575 1 10.14071753 -4.25884672 24.99642009 0.940464672 1.447518021 0.810293215 0.075845435 67.50390797 650782.0669 0.009082105 0.083271505 5.51E-05 4.25884672 0.507053349 MEDEGGFPVPQENGQPES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 MEDEGGFPVPQENGQPESPR 20 0 J3KPS2;A0A494C1T9;Q6ZRV2 J3KPS2 FAM83H Protein FAM83H 1 0 MEDEGGFPVPQENGQPES(1)PR;MEDEGGFPVPQENGQPES(1)PR ; 190.79 3.11E-10 8650200 1728.6 1655.32 1637.35 1926.79 2030.24 2585.82 2307.99 928.67 2056.39 1990.43 TRUE FALSE FALSE 1591.779486 1798.398485 1698.031631 1918.817454 2006.030714 2049.491784 2372.745988 1211.817208 1830.809162 2059.597294 0.772859573 0.87317967 0.82444837 0.931646909 0.973991721 0.995093453 1.152043652 0.588375801 0.888916084 1 11.00814656 -6.020240479 22.15490978 0.883339805 0.948830621 0.026117007 0.142623473 511.3457439 559714.3189 0.022067937 0.036977421 9.54E-07 6.020240479 0.065490816 MEEDS(ph)IRLPAHLR ddPTM_HeLa_Curcumin_4h_R1 2 MEEDSIRLPAHLR 13 1 P41212;H0YG25 P41212 ETV6 Transcription factor ETV6 1 0 MEEDS(1)IRLPAHLR;MEEDS(1)IRLPAHLR ; 99.815 0.0062402 0 1152.29 897.98 927.08 1058.17 1133.94 1354.16 906.41 2764.4 1233.25 826.74 TRUE FALSE FALSE 1061.085031 975.5973899 961.4384003 1053.791573 1120.418506 1073.291951 931.8414251 3607.252834 1097.96556 855.4691535 1.240354519 1.140423808 1.123872669 1.231828838 1.309712339 1.25462379 1.089275307 4.216695388 1.283465986 1 9.740572025 -4.260782845 24.99957301 1.147267524 4.216696332 0.98827437 0.098956853 4.487489002 170837.626 0.016171059 0.128980806 5.49E-05 4.260782845 3.069428808 MEES(ph)DEEAVQAK ddPTM_HeLa_Curcumin_4h_R1 4 MEESDEEAVQAK 12 0 I3VM54;Q9Y2K7-3;Q9Y2K7;Q9Y2K7-4;Q9Y2K7-5;Q9Y2K7-2 I3VM54 KDM2A Lysine-specific demethylase 2A 1 0 MEES(1)DEEAVQAK;MEES(1)DEEAVQAK;MEES(1)DEEAVQAK;MEES(1)DEEAVQAK ;;; 190.1 5.84E-06 43271000 17208.7 14156.2 15446.9 17132.3 17047.5 17422.3 13916.3 9952 17203.7 15754 TRUE FALSE FALSE 15846.61324 15379.79885 16019.3757 17061.41108 16844.2197 13808.71859 14306.75392 12986.31899 15316.49715 16301.45033 0.972098367 0.943461995 0.982696348 1.046619211 1.033295772 0.847085278 0.877636875 0.796635804 0.939578801 1 13.99271271 -5.249887401 24.54810678 0.990168618 0.844171051 0.770356991 0.03695205 194.998976 414374.0888 0.004916332 0.012413486 5.62E-06 5.249887401 -0.145997566 MEFHLIPHS(ph)LPGFPDTQTIR ddPTM_HeLa_Curcumin_4h_R1 1 MEFHLIPHSLPGFPDTQTIR 20 0 Q86Y01 Q86Y01 DTX1 E3 ubiquitin-protein ligase DTX1 1 0 MEFHLIPHS(1)LPGFPDTQTIR 58.864 0.0088013 1173000 817.07 791.17 640.62 712.32 538.63 771.42 478.86 457.23 568.55 705.67 TRUE FALSE FALSE 752.3980473 859.5552094 664.3619407 709.3726086 532.207189 611.4187963 492.2955228 596.6373222 506.1814874 730.19198 1.030411273 1.177163312 0.909845573 0.971487811 0.728859264 0.837339786 0.674200123 0.817096515 0.693216991 1 9.512132013 -5.928642524 1.911788871 1.023917687 0.758631554 0.302045955 0.12950481 0.125725654 0.925875142 0.01104472 0.022677086 1.18E-06 5.928642524 -0.265286134 MEIDESNAGS(ph)SKEEAGETSPADESGAPK ddPTM_HeLa_Curcumin_4h_R1 1 MEIDESNAGSSKEEAGETSPADESGAPK 28 1 Q9UKY1 Q9UKY1 ZHX1 Zinc fingers and homeoboxes protein 1 1 0 MEIDES(0.028)NAGS(0.467)S(0.467)KEEAGET(0.007)S(0.031)PADESGAPK 60.139 0.0061997 8293800 2373.2 1754.9 1987.4 1602.9 1835.8 1997.5 1803 1409.1 1842.9 1983 TRUE FALSE FALSE 2185.358716 1906.585736 2061.054792 1596.267625 1813.909284 1583.195984 1853.587327 1838.728103 1640.738481 2051.909102 1.065036806 0.929176509 1.004457161 0.77794266 0.884010545 0.771572182 0.90334768 0.896106022 0.799615577 1 11.00275111 -6.540629205 1.872201431 1.027022377 0.848596288 0.066713282 0.091980969 0.145644149 1.024557899 0.009304485 0.014650638 2.88E-07 6.540629205 -0.178426089 MEIDESNAGSSKEEAGET(ph)SPADESGAPK ddPTM_HeLa_Curcumin_4h_R1 2 MEIDESNAGSSKEEAGETSPADESGAPK 28 1 Q9UKY1 Q9UKY1 ZHX1 Zinc fingers and homeoboxes protein 1 1 0 MEIDESNAGS(0.001)S(0.004)KEEAGET(0.532)S(0.422)PADES(0.04)GAPK;MEIDES(0.001)NAGS(0.001)S(0.001)KEEAGET(0.499)S(0.499)PADESGAPK ; 75.896 7.56E-05 10207000 2541.7 2239.08 2438 2931.8 2395.85 3102.9 2471.1 1942.17 3133.3 3035.7 TRUE FALSE FALSE 2340.521763 2432.616098 2528.354425 2919.668988 2367.281054 2459.323563 2540.432415 2534.328692 2789.584829 3141.190349 0.745106632 0.774424924 0.804903283 0.92947853 0.75362547 0.782927263 0.808748319 0.806805195 0.888066153 1 11.61709565 -9.367243812 1.032324917 1.002809909 0.798405946 0.453807636 0.058252769 0.24545954 0.457865557 0.037371395 0.009161853 4.29E-10 9.367243812 -0.204403963 MEIGDTLSTAEES(ph)SPPK ddPTM_HeLa_Curcumin_4h_R1 3 MEIGDTLSTAEESSPPK 17 0 Q9BYW2;C9JG86;Q9BYW2-3;Q9BYW2-2 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 0 MEIGDTLS(0.002)T(0.013)AEES(0.878)S(0.108)PPK;MEIGDTLS(0.004)T(0.029)AEES(0.704)S(0.263)PPK;MEIGDTLSTAEES(0.92)S(0.08)PPK ;; 150.12 0.00025863 44860000 9784.4 8594.4 9435.3 9388.8 9854 10076 8389.3 4033.86 8366.6 6661.4 TRUE FALSE FALSE 9009.954416 9337.26164 9784.980518 9349.951633 9736.497486 7986.12402 8624.681179 5263.765344 7448.804912 6892.883154 1.307138713 1.35462352 1.419577309 1.356464548 1.412543528 1.158604294 1.251244361 0.763652194 1.080651557 1 12.75089184 -2.935852633 13.80978865 1.197370054 1.201215761 0 0.200713505 0 0 0.028528716 0 0.001159171 2.935852633 0.003845706 MELAGSNTTASS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 2 MELAGSNTTASSPAR 15 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9;A0A0C4DGI9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 0 MELAGSNTTAS(0.211)S(0.789)PAR;MELAGSNT(0.001)T(0.002)AS(0.124)S(0.873)PAR ; 145.49 0.00048731 52694000 5986.7 5565.9 5638.3 5697 5454.3 7531.7 6006.6 1192.76 7919.2 5622.9 TRUE FALSE FALSE 5512.846378 6046.991595 5847.260358 5673.427324 5389.261035 5969.54052 6175.12903 1556.427033 7050.483573 5818.295356 0.947501981 1.039306399 1.004978262 0.975101293 0.926261165 1.025994755 1.061329591 0.267505676 1.211778217 1 12.50638082 -4.257752258 24.99992109 0.985426536 0.267505403 0.881514117 0.081966629 45.83182242 310741.7892 0.005802565 0.05758978 5.52E-05 4.257752258 -0.717921132 MELQEIQLK ddPTM_HeLa_Curcumin_4h_R1 2 MELQEIQLK 9 0 A0A087WWU8;P06753-2;P06753-5;P06753-3;P06753-6;P06753-4;P06753-7;J3KN67;A0A494C0P6;A0A2R2Y2Q3;P06753 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 0 ; ; 116.52 0.0016181 3237400 2271.7 2128.55 2595.8 2581.5 2239.55 2814.9 2333.36 1914.73 2733.5 2216.65 FALSE FALSE TRUE 2091.892548 2312.532377 2692.002631 2570.818437 2212.844829 2231.05801 2398.827802 2498.522363 2433.641889 2293.678423 0.912025211 1.008219964 1.17366175 1.120827755 0.964758097 0.972698696 1.045843122 1.089308047 1.061021399 1 11.16344742 -7.00003218 25 0.958544043 1.057804241 0.131673757 0.069867896 1.078065884 837960.2833 0.011356633 0.014841211 1.00E-07 7.00003218 0.099260198 MENIIDQCLQKPADVIGK ddPTM_HeLa_Curcumin_4h_R1 1 MENIIDQCLQKPADVIGK 18 1 Q9UJX5;Q9UJX5-3 Q9UJX5 ANAPC4 Anaphase-promoting complex subunit 4 0 0 87.148 0.0088416 2348200 1011.6 739.03 1513.5 1627.3 763.75 354.53 252.02 205.17 123.03 0 FALSE FALSE TRUE 931.5307926 802.9084601 1569.591641 1620.566664 754.6427801 280.9964816 259.0910029 267.7253885 109.5339168 0 0 MEREDS(ph)S(ph)EEEEEEIDDEEIER ddPTM_HeLa_Curcumin_4h_R1 2 MEREDSSEEEEEEIDDEEIER 21 1 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 2 0 MEREDS(1)S(1)EEEEEEIDDEEIER;MEREDS(1)S(1)EEEEEEIDDEEIER ; 131.98 4.85E-05 85280000 2394.4 1794.33 2263.04 2107.29 2546.8 5012.2 4471.7 2294.9 4536.5 3082.2 TRUE FALSE FALSE 2204.880713 1949.42389 2346.910253 2098.570592 2516.431073 3972.613221 4597.163867 2994.604446 4038.8573 3189.306221 0.691335532 0.611237603 0.735868584 0.658002226 0.789021467 1.245604199 1.44143069 0.938951684 1.266374885 1 11.63902691 -5.261295838 24.99435455 0.804452643 1.231939063 0.404213953 0.214019431 7.607817494 1324564.468 0.026099246 0.062213969 5.48E-06 5.261295838 0.427486421 MES(ph)HS(ph)EDEDLAGAVGGLGWNSR ddPTM_HeLa_Curcumin_4h_R1 1 MESHSEDEDLAGAVGGLGWNSR 22 0 K7ESM2;K7ELS4;K7EJA3;K7ERG7;Q96MH2;K7EIM4 K7ESM2 HEXIM2 Protein HEXIM2 2 0 MES(1)HS(1)EDEDLAGAVGGLGWNSR 68.458 0.0020056 0 932.86 978.01 1123.8 1088 1001 1083.5 937.18 970.78 1170.3 929.94 TRUE FALSE FALSE 859.0231467 1062.544826 1165.449017 1083.498144 989.0637288 858.7698864 963.4747485 1266.766353 1041.921018 962.2553458 0.892718498 1.104223355 1.211163982 1.125998571 1.027859947 0.892455303 1.001267234 1.316455511 1.082790574 1 9.910275971 -7.250595794 24.18656873 0.949339291 1.088346805 0.108621993 0.119157051 509.2183176 1135809.294 0.019580148 0.023842534 5.62E-08 7.250595794 0.139007514 MESEGGADDS(ph)AEEGDLLDDDDNEDR ddPTM_HeLa_Curcumin_4h_R1 1 MESEGGADDSAEEGDLLDDDDNEDR 25 0 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 0 MES(0.001)EGGADDS(0.999)AEEGDLLDDDDNEDR 114.73 1.78E-08 6352500 1285.4 1409.1 1562.1 1202.6 1313 1484.9 1394.2 1156.9 1029.6 1070.9 TRUE FALSE FALSE 1183.659234 1530.896325 1619.9928 1197.62396 1297.343333 1176.915002 1433.3175 1509.633484 916.6554559 1108.113695 1.068174898 1.38153362 1.461937351 1.080777149 1.170767348 1.062088671 1.293475124 1.3623453 0.827221484 1 10.1138902 -7.420479213 6.107703121 1.029636727 1.250035635 0.473003499 0.137466777 0.180412997 9.018312831 0.022146257 0.025158689 3.80E-08 7.420479213 0.220398908 MESLSSHRIDEDGENTQIEDTEPMS(ph)PVLNSK ddPTM_HeLa_Curcumin_4h_R1 1 MESLSSHRIDEDGENTQIEDTEPMSPVLNSK 31 1 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 MES(0.136)LS(0.136)S(0.136)HRIDEDGENT(0.12)QIEDT(0.028)EPMS(0.42)PVLNS(0.023)K 41.65 0.0092047 9227500 1054.4 921.46 656.02 694.33 992.46 2506.7 984.89 928.08 1852 911.41 TRUE FALSE FALSE 970.9431274 1001.106896 680.3326783 691.4570464 980.6255627 1986.782164 1012.523363 1211.04732 1648.840233 943.0814297 1.029543258 1.061527526 0.721393357 0.733189123 1.039810065 2.106692064 1.073633019 1.284138656 1.748354046 1 9.881238534 -5.49067586 24.99033471 0.972720526 1.467793947 0.218097172 0.364868549 464.2977802 360307.6898 0.036788177 0.082192627 3.23E-06 5.49067586 0.495073422 MESMNRPYTSLVPPLS(ph)PQPK ddPTM_HeLa_Curcumin_4h_R1 4 MESMNRPYTSLVPPLSPQPK 20 1 C9K0J5;Q70E73 C9K0J5 RAPH1 Ras-associated and pleckstrin homology domains-containing protein 1 1 0 MES(0.004)MNRPY(0.004)T(0.005)S(0.005)LVPPLS(0.983)PQPK;MES(0.004)MNRPY(0.078)T(0.09)S(0.09)LVPPLS(0.738)PQPK;MESMNRPYT(0.002)S(0.001)LVPPLS(0.998)PQPK;MESMNRPY(0.001)T(0.006)S(0.006)LVPPLS(0.988)PQPK ;;; 98.169 0.00029045 163591000 8101.2 6002.4 6797.6 6476.1 5410.07 5745.1 4186.83 7786.1 7105.1 7036.7 TRUE FALSE FALSE 7459.981472 6521.22071 7049.525036 6449.303614 5345.558449 4553.501499 4304.301182 10160.04605 6325.688306 7281.224801 1.024550357 0.895621394 0.968178463 0.885744334 0.734156491 0.625375761 0.591150706 1.39537596 0.868767066 1 12.82996544 -6.375943089 1.543579351 1.005888572 0.807745224 0.025056962 0.215209447 0.53603133 2.513203397 0.033110502 0.057792873 4.21E-07 6.375943089 -0.198143348 MET(ph)EADAPSPAPS(ph)LGER ddPTM_HeLa_Curcumin_4h_R1 3 METEADAPSPAPSLGER 17 0 Q12873-2;Q12873;Q12873-3 Q12873-2 CHD3 Chromodomain-helicase-DNA-binding protein 3 2 0 MET(0.955)EADAPS(0.045)PAPS(1)LGER;MET(0.983)EADAPS(0.017)PAPS(1)LGER;MET(0.653)EADAPS(0.347)PAPS(1)LGER ;; 150.61 0.00097043 25587000 6115.4 5514.6 6104.9 7070.6 6640.5 7378.5 6751.2 4902.9 5877.9 6438.7 TRUE FALSE FALSE 5631.359637 5991.257451 6331.152964 7041.343731 6561.316375 5848.115927 6940.620502 6397.77164 5233.109076 6662.444346 0.845239276 0.899258161 0.950274799 1.056870927 0.984821191 0.877773325 1.041752868 0.960273934 0.785463833 1 12.70183586 -6.519287023 24.47186781 0.922895577 0.983798491 0.24244434 0.072052676 177.723596 1210905.13 0.011383683 0.016306191 3.02E-07 6.519287023 0.060902914 MET(ph)EADAPSPAPS(ph)LGERLEPR ddPTM_HeLa_Curcumin_4h_R1 1 METEADAPSPAPSLGERLEPR 21 1 Q12873-2;Q12873;Q12873-3 Q12873-2 CHD3 Chromodomain-helicase-DNA-binding protein 3 2 0 MET(0.677)EADAPS(0.323)PAPS(1)LGERLEPR 66.772 0.0048395 10557000 927.5 679.96 763.49 940.05 941.04 1102.4 1017.2 747.98 1423.1 1141.5 TRUE FALSE FALSE 854.0873963 738.7327126 791.785611 936.1603222 929.8187126 873.7498134 1045.739894 976.0356587 1266.98949 1181.16704 0.723087732 0.625426115 0.670341776 0.792572338 0.787203402 0.739734334 0.885344629 0.826331607 1.072659029 1 10.20599729 -9.201972206 0.979288477 0.997755454 0.755270978 0.672084341 0.076371292 0.306377282 0.535228549 0.050590122 0.014741258 6.28E-10 9.201972206 -0.242484476 MET(ph)EADAPSPAPSLGER ddPTM_HeLa_Curcumin_4h_R1 1 METEADAPSPAPSLGER 17 0 Q12873-2;Q12873;Q12873-3 Q12873-2 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 0 MET(0.964)EADAPS(0.036)PAPSLGER 118.2 0.019082 23412000 3583.6 3248.3 3319.6 3786.5 3520.7 3920.9 3583.7 1933.8 4333.2 3048.5 TRUE FALSE FALSE 3299.954279 3529.068578 3442.627296 3770.832466 3478.717952 3107.661142 3684.248977 2523.406718 3857.858801 3154.435148 1.046131597 1.11876403 1.091360936 1.195406559 1.102802178 0.985171987 1.167958384 0.799955174 1.222995123 1 11.62316598 -4.244676354 24.60523969 1.055137776 0.799954925 0.448164773 0.087309065 1761.638514 2585733.273 0.010486238 0.38317507 5.69E-05 4.244676354 -0.255182852 METEADAPS(ph)PAPS(ph)LGER ddPTM_HeLa_Curcumin_4h_R1 1 METEADAPSPAPSLGER 17 0 Q12873-2;Q12873;Q12873-3 Q12873-2 CHD3 Chromodomain-helicase-DNA-binding protein 3 2 0 MET(0.217)EADAPS(0.784)PAPS(0.999)LGER 79.326 0.011775 9213700 2084 2111.2 2185.9 2563.4 2731.3 3771.3 3094.9 2157.6 2497.7 2678.9 TRUE FALSE FALSE 1919.049201 2293.682721 2266.911377 2552.79333 2698.731031 2989.089869 3181.734565 2815.442308 2223.708559 2771.991576 0.692299796 0.827449384 0.817791582 0.920923914 0.973571152 1.078318526 1.14781538 1.015674915 0.802206103 1 11.43670716 -5.630391288 1.718729461 0.846685361 1.089280285 0.657636073 0.078402767 0.259409368 1.53593551 0.018188263 0.046155314 2.34E-06 5.630391288 0.242594924 METEADAPS(ph)PAPS(ph)LGERLEPR ddPTM_HeLa_Curcumin_4h_R1 2 METEADAPSPAPSLGERLEPR 21 1 Q12873-2;Q12873;Q12873-3 Q12873-2 CHD3 Chromodomain-helicase-DNA-binding protein 3 2 0 MET(0.005)EADAPS(0.995)PAPS(1)LGERLEPR;MET(0.002)EADAPS(0.998)PAPS(1)LGERLEPR ; 71.872 0.00203 26282000 7277.9 6610.4 6280.2 8686.9 5641.5 10097.4 7896.5 5225.7 10587.9 10295.7 TRUE FALSE FALSE 6701.846535 7181.773521 6512.949737 8650.95591 5574.228797 8003.085419 8118.054538 6818.991874 9426.43386 10653.47481 0.629076114 0.674124983 0.611345111 0.812031386 0.523231049 0.751218317 0.762010019 0.640072089 0.884822467 1 13.37903645 -9.270135599 0.872609126 1.01152965 0.675463161 0.595227025 0.086133281 0.27055154 0.349769939 0.060953958 0.014513135 5.37E-10 9.270135599 -0.336066489 METEADAPS(ph)PAPSLGER ddPTM_HeLa_Curcumin_4h_R1 6 METEADAPSPAPSLGER 17 0 Q12873-2;Q12873;Q12873-3 Q12873-2 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 0 METEADAPS(1)PAPSLGER;METEADAPS(1)PAPSLGER;MET(0.075)EADAPS(0.914)PAPS(0.011)LGER;METEADAPS(1)PAPSLGER;METEADAPS(1)PAPSLGER;METEADAPS(0.986)PAPS(0.013)LGER ;;;;; 270.94 1.53E-52 548505900 26534.5 21127.1 20845.9 24280.7 22283.4 27219.9 22200.3 11736.44 25465.8 21063.6 TRUE FALSE FALSE 24434.26633 22953.23238 21618.46739 24180.2329 22017.68501 21574.18591 22823.18067 15314.82653 22672.26545 21795.55853 1.121066308 1.053115127 0.991874898 1.109411023 1.010191364 0.989843223 1.047148236 0.702658136 1.040224109 1 14.41174655 -4.261202921 8.096666347 1.049061656 0.699996546 0.838605452 0.044290881 0.031669718 26.26017476 0.007496358 0.059627317 5.48E-05 4.261202921 -0.34906511 METEADAPSPAPS(ph)LGER ddPTM_HeLa_Curcumin_4h_R1 1 METEADAPSPAPSLGER 17 0 Q12873-2;Q12873;Q12873-3 Q12873-2 CHD3 Chromodomain-helicase-DNA-binding protein 3 1 0 MET(0.003)EADAPS(0.135)PAPS(0.861)LGER 78.166 0.012244 4467600 1493 1092.7 1218.5 1143.5 1438 1249.9 1112.5 698.15 1375.1 1147.3 TRUE FALSE FALSE 1374.827475 1187.148119 1263.658682 1138.7685 1420.852789 990.6566507 1143.713756 911.0127211 1224.25497 1187.16859 1.15807265 0.999982757 1.064430691 0.959230652 1.196841629 0.834470065 0.96339624 0.76738277 1.031239355 1 10.21330911 -4.366312529 0.811547166 1.069139649 0.653525599 0.472966345 0.089888982 1.365324928 0.712741168 0.014852856 0.491767326 4.30E-05 4.366312529 -0.41561405 METVSNASSSS(ph)NPS(ph)SPGR ddPTM_HeLa_Curcumin_4h_R1 1 METVSNASSSSNPSSPGR 18 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 2 0 METVSNAS(0.001)S(0.003)S(0.028)S(0.969)NPS(0.601)S(0.399)PGR 166.36 3.80E-05 29643000 3918.2 3387 3350.8 3971.2 3590.6 5002.8 4698.9 2825.3 4351.2 4046.9 TRUE FALSE FALSE 3608.070336 3679.757188 3474.983596 3954.768227 3547.78444 3965.162887 4830.738488 3686.720964 3873.884246 4187.529474 0.861622672 0.8787418 0.829840988 0.944415616 0.847226142 0.946897905 1.153601071 0.88040478 0.925100174 1 12.03188363 -4.983889692 24.99354946 0.915870441 1.025314599 0.245112837 0.078656554 269.9528517 418799.7731 0.011576546 0.034715124 1.04E-05 4.983889692 0.109444158 METVSNASSSS(ph)NPSS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 3 METVSNASSSSNPSSPGR 18 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 2 0 METVS(0.001)NAS(0.029)S(0.038)S(0.169)S(0.763)NPS(0.02)S(0.98)PGR;METVS(0.003)NAS(0.068)S(0.09)S(0.357)S(0.481)NPS(0.029)S(0.971)PGR;METVSNASS(0.001)S(0.019)S(0.979)NPS(0.044)S(0.956)PGR ;; 208.59 4.86E-12 59340000 11792.2 9515.4 10548.8 12667.1 11062.3 14087 12826.7 11042.8 12859.9 13625.9 TRUE FALSE FALSE 10858.83493 10337.86878 10939.74781 12614.6869 10930.3893 11165.19741 13186.58268 14409.69889 11449.20114 14099.39901 0.770162964 0.733213435 0.77590171 0.89469678 0.775237958 0.791891725 0.935258494 1.022008021 0.812034693 1 13.78334605 -2.875627805 14.73568769 0.868027466 43.90362019 0 0.100069575 0 0 0.015829819 0 0.001331595 2.875627805 43.03559272 METVSNASSSSNPS(ph)SPGR ddPTM_HeLa_Curcumin_4h_R1 2 METVSNASSSSNPSSPGR 18 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 METVSNASSSSNPS(0.5)S(0.5)PGR;METVSNASSSSNPS(0.774)S(0.226)PGR ; 351.47 3.34E-174 327879000 7634.8 5682.5 5465.2 7041.8 6790.7 6938.8 6144.5 3551.7 7436.6 5881.3 TRUE FALSE FALSE 7030.497524 6173.669979 5667.74512 7012.662897 6709.725338 5499.614664 6316.898133 4634.59698 6620.823585 6085.674737 1.155253579 1.014459406 0.931325673 1.152322988 1.102544192 0.903698423 1.037994702 0.761558443 1.087935828 1 12.57120151 -3.52532322 0.940346892 1.064500044 3.72E-14 0.51684718 0.081027436 4.56053323 1.132634627 0.013604306 6.917354332 0.000298316 3.52532322 -1.064500044 METVSNASSSSNPSS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 9 METVSNASSSSNPSSPGR 18 0 Q9NTI5-2;Q9NTI5;A9IYQ1 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 METVSNASSS(0.002)S(0.001)NPS(0.137)S(0.861)PGR;METVSNASSSSNPS(0.002)S(0.998)PGR;METVSNASSSSNPS(0.012)S(0.988)PGR;METVSNASSSSNPS(0.041)S(0.959)PGR;METVSNASSSSNPS(0.052)S(0.948)PGR;METVSNASSSSNPS(0.042)S(0.958)PGR;METVSNASSSSNPS(0.227)S(0.773)PGR;METVSNAS(0.006)S(0.006)S(0.004)S(0.004)NPS(0.2)S(0.779)PGR;METVSNASSSSNPS(0.006)S(0.994)PGR ;;;;;;;; 357.96 7.22E-175 491840000 32175.48 24753.41 27654.8 32819.23 28402.67 33370.44 27988.82 17354.56 34348.63 29073.94 TRUE FALSE FALSE 29628.75681 26892.98446 28679.71122 32683.43272 28063.98671 26449.03458 28774.11096 22645.88545 30580.67123 30084.25725 0.984859176 0.893922168 0.953312923 1.086396531 0.932846255 0.879165284 0.956450768 0.752748697 1.016500789 1 14.87672112 -3.236226015 0.7465058 0.985803385 6.72E-13 0.565371711 0.056699303 5.541832235 0.706630878 0.008914359 6.567494381 0.000580462 3.236226015 -0.985803385 MEVGPFSTGQES(ph)PTAENAR ddPTM_HeLa_Curcumin_4h_R1 1 MEVGPFSTGQESPTAENAR 19 0 Q9Y4W2-3;Q9Y4W2-2;Q9Y4W2 Q9Y4W2-3 LAS1L Ribosomal biogenesis protein LAS1L 1 0 MEVGPFSTGQES(0.993)PT(0.007)AENAR 203.17 2.33E-13 7466600 450.36 482.96 521.87 430.57 668.97 656.42 368.11 366.66 387.4 556.82 TRUE FALSE FALSE 414.7135308 524.7049104 541.2109613 428.7884154 660.9929697 520.2710926 378.4381759 478.4529461 344.9031892 576.1694536 0.719777017 0.910678112 0.939326023 0.744205394 1.147219738 0.902982776 0.656817493 0.830403179 0.598614153 1 9.170349366 -9.671694587 1.54119728 0.999671275 0.839269909 0 0.180466811 0.597851143 2.565026274 0.096475542 0.021771556 2.13E-10 9.671694587 -0.160401366 MEY(ph)QLLDIK ddPTM_HeLa_Curcumin_4h_R1 1 MEYQLLDIK 9 0 K7EMN5 K7EMN5 DYNAP 1 0 MEY(1)QLLDIK 107.69 0.0064432 0 2219.6 1833.3 2192.1 2183.1 2075.4 2766.2 1839.6 2513.3 2250 2105.9 TRUE FALSE FALSE 2043.916318 1991.762283 2273.341154 2174.066911 2050.65221 2192.458939 1891.214225 3279.5936 2003.180629 2179.079868 0.937972191 0.91403822 1.04325738 0.997699507 0.941063354 1.00613978 0.867895781 1.505035978 0.919278205 1 11.08950336 -4.254864729 24.99782058 0.968266328 1.50503622 0.911521492 0.050994042 144.7159389 550217.3032 0.006513825 0.083431418 5.56E-05 4.254864729 0.536769892 MFGGPGTAS(ph)RPSSSR ddPTM_HeLa_Curcumin_4h_R1 1 MFGGPGTASRPSSSR 15 1 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 0 MFGGPGT(0.002)AS(0.448)RPS(0.025)S(0.448)S(0.077)R 88.78 0.016891 6567500 2166.5 1793.2 1805.4 1909.8 1763.7 2071.2 2163.8 1835.2 2194.6 1774.5 TRUE FALSE FALSE 1995.019239 1948.196218 1872.309712 1901.897754 1742.669029 1641.609773 2224.510404 2394.744032 1953.857871 1836.163743 1.086514886 1.061014425 1.019685591 1.035799645 0.949081495 0.894043235 1.211498927 1.304210499 1.064097839 1 10.842479 -4.588094201 6.342750571 1.027030282 1.282384291 0.756906791 0.055977355 0.070933993 5.1479367 0.008625599 0.033449398 2.58E-05 4.588094201 0.255354009 MFGGPGTASRPSS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 MFGGPGTASRPSSSR 15 1 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 0 MFGGPGT(0.001)AS(0.071)RPS(0.008)S(0.727)S(0.192)R 88.706 0.017008 6265000 4257.4 2907.5 3279.2 3369.8 3068.5 4027.8 4090.5 3323.5 4659.7 3241.7 TRUE FALSE FALSE 3920.422298 3158.811344 3400.730037 3355.85666 3031.910142 3192.388877 4205.268421 4336.81985 4148.542568 3354.348834 1.168758079 0.941706275 1.013827185 1.000449514 0.90387443 0.951716424 1.253676534 1.292894706 1.236765397 1 11.71181701 -4.685101648 6.952847219 1.041778582 1.279402868 0.498393461 0.098013676 0.141632459 10.51929316 0.013619261 0.051650274 2.06E-05 4.685101648 0.237624286 MFIK(ac)MSQPK(ac)K(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 MFIKMSQPKKR 11 3 A0A494C0M7 A0A494C0M7 0 3 MFIK(1)MSQPK(1)K(1)R 57.836 0.02024 5616400 2339.6 1465.6 1554.6 1683.3 1188.3 2796.3 1513.6 1926 2789.5 2886.5 FALSE TRUE FALSE 2154.418191 1592.279933 1612.214844 1676.334951 1174.130299 2216.315859 1556.067542 2513.228534 2483.498829 2986.80566 0.721311808 0.533104632 0.539778957 0.561246744 0.39310569 0.742035509 0.520980512 0.841443609 0.83148993 1 11.54438765 -8.288552984 0.754384501 0.973067682 0.58331933 0.475182476 0.12930287 0.271573188 0.331624654 0.048471337 0.027939887 5.15E-09 8.288552984 -0.389748352 MFVSSSGLPPS(ph)PVPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 MFVSSSGLPPSPVPSPR 17 0 Q7Z309;Q7Z309-2;G1UD79;Q7Z309-5;Q7Z309-4;Q7Z309-3 Q7Z309 FAM122B;SPACIA2 Protein FAM122B 2 0 MFVS(0.009)S(0.002)S(0.001)GLPPS(0.988)PVPS(1)PR 92.096 0.0044266 7885300 1403.8 1051.6 1153.9 1159.1 1276.2 1507 1251.2 887.26 1175.3 1031.9 TRUE FALSE FALSE 1292.687749 1142.495618 1196.664549 1154.303951 1260.982149 1194.431213 1286.305305 1157.78149 1046.37253 1067.758448 1.210655604 1.069994454 1.120725901 1.081053447 1.180961996 1.118634289 1.20467818 1.084310306 0.979971203 1 10.0603696 -9.527514999 1.264530273 0.999442673 1.142160488 0.568892303 0.049216186 0.287480187 0.817920035 0.035522115 0.008362631 2.97E-10 9.527514999 0.142717815 MGAGLGHGMDR ddPTM_HeLa_Curcumin_4h_R1 2 MGAGLGHGMDR 11 0 A0A087X0X3;P52272-2;P52272;M0R2T0;M0QZM1 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 0 ; ; 60.167 0.018758 5514080 4562.74 3186.14 3512.76 3359.94 4042.37 4489.53 3312.35 2836.97 3889.54 3596.7 FALSE FALSE TRUE 4201.594314 3461.535744 3642.945976 3346.037459 3994.167378 3558.350871 3405.285626 3701.949093 3462.867193 3721.685057 1.128949454 0.930099052 0.978843164 0.899065183 1.073214771 0.95611284 0.914984899 0.994697035 0.930456806 1 11.86174026 -7.248566454 24.86530619 1.060892799 0.963971987 0.031532629 0.068025092 611.5104163 1181191.865 0.010557396 0.012887861 5.64E-08 7.248566454 -0.096920812 MGAPESGLAEYLFDKHTLGDS(ph)DNES ddPTM_HeLa_Curcumin_4h_R1 1 MGAPESGLAEYLFDKHTLGDSDNES 25 1 G3V1D1;G3V192;P02794 G3V1D1 FTH1 "Ferritin;Ferritin heavy chain;Ferritin heavy chain, N-terminally processed" 1 0 MGAPESGLAEY(0.002)LFDKHT(0.101)LGDS(0.449)DNES(0.449) 70.072 0.00033013 63620000 2006.5 1562.4 1493.9 1726 1794.2 2408.4 1726.2 1340.8 1962.1 1697 TRUE FALSE FALSE 1847.683408 1697.446894 1549.265248 1718.858269 1772.805337 1908.870692 1774.632526 1749.603748 1746.862539 1755.970624 1.052229111 0.966671578 0.882284263 0.978865048 1.009587127 1.087074388 1.010627685 0.996374156 0.994813077 1 10.77805299 -2.970290869 13.37704481 1.010463857 1.003766669 0 0.052453333 0 0 0.007546905 0 0.001070802 2.970290869 -0.006697189 MGAPESGLAEYLFDKHTLGDSDNES(ph) ddPTM_HeLa_Curcumin_4h_R1 1 MGAPESGLAEYLFDKHTLGDSDNES 25 1 G3V1D1;G3V192;P02794 G3V1D1 FTH1 "Ferritin;Ferritin heavy chain;Ferritin heavy chain, N-terminally processed" 1 0 MGAPESGLAEY(0.002)LFDKHT(0.02)LGDS(0.142)DNES(0.836) 59.094 0.0024303 34844000 1114.6 1089.1 1038.2 943.37 910.21 1197.1 892.8 927.13 1311.2 1004.5 TRUE FALSE FALSE 1026.378234 1183.236951 1076.676605 939.4665849 899.3563402 948.8079659 917.8495652 1209.807669 1167.36464 1039.4063 0.987465858 1.138377698 1.035857301 0.903849231 0.865259658 0.912836458 0.883051762 1.163941058 1.123107143 1 10.02154399 -6.264355675 24.99983344 1.009897003 0.93599791 0.17383877 0.09588229 399.7107346 3426499.063 0.01332843 0.020928795 5.44E-07 6.264355675 -0.073899094 MGES(ph)DDSILR ddPTM_HeLa_Curcumin_4h_R1 1 MGESDDSILR 10 0 Q8WVC2;P63220 Q8WVC2 RPS21 40S ribosomal protein S21 1 0 MGES(1)DDSILR 100.09 0.01252 2694100 1003.5 1013 1009.4 1121.2 1028.1 2341.2 1645.3 391.16 1329.3 1078.1 TRUE FALSE FALSE 924.0719161 1100.559206 1046.809252 1116.560771 1015.840579 1855.608729 1691.46269 510.4228833 1183.479116 1115.563895 0.828345127 0.986549682 0.938367813 1.000893608 0.910607258 1.663381845 1.516240081 0.457546973 1.060879723 1 10.12355743 -5.399335993 19.01953153 0.929668954 1.25024165 0.117907409 0.301834042 3.564460788 535.4043127 0.040080563 0.089623059 3.99E-06 5.399335993 0.320572696 MGESDDS(ph)ILR ddPTM_HeLa_Curcumin_4h_R1 1 MGESDDSILR 10 0 Q8WVC2;P63220 Q8WVC2 RPS21 40S ribosomal protein S21 1 0 MGES(0.034)DDS(0.966)ILR 100.69 0.012121 1856000 1039.5 1194 1001.4 1350.9 1352.1 1558.9 1004.1 1158.7 1495.3 1086.6 TRUE FALSE FALSE 957.2224781 1297.20404 1038.512765 1345.310334 1335.977091 1235.566568 1032.272344 1511.982296 1331.269331 1124.359269 0.851349301 1.15372735 0.923648511 1.196512868 1.188211924 1.098907263 0.918098309 1.34475015 1.184024864 1 10.13488738 -6.773760498 1.408919277 0.934059659 1.128153167 0 0.149926563 0.357207718 1.42997232 0.022581138 0.033226531 1.68E-07 6.773760498 0.194093508 MGGEEK(ac)PIGAGEEK ddPTM_HeLa_Curcumin_4h_R1 3 MGGEEKPIGAGEEK 14 1 P26639;P26639-2;D6RCA5;D6R9F8;D6RDJ6;D6RJ97;D6RHV7;D6RCS6 P26639 TARS "Threonine--tRNA ligase, cytoplasmic" 0 1 ;; MGGEEK(1)PIGAGEEK;MGGEEK(1)PIGAGEEK;MGGEEK(1)PIGAGEEK 177.36 9.67E-08 9002100 5580.65 6868.13 5143.45 4405.29 10280.68 12364.46 9639.86 9395.35 12727.34 5736.83 FALSE TRUE FALSE 5138.935664 7461.780553 5334.070782 4387.062077 10158.08961 9799.93162 9910.328527 12259.94896 11331.18264 5936.184415 0.865696768 1.256999451 0.898568914 0.739037363 1.711215302 1.650880588 1.669477872 2.065291121 1.908832653 1 12.5353202 -5.749924066 24.42115617 0.946290165 1.757925614 0.426907844 0.345481762 44.01372167 93341.41995 0.023397163 0.046457436 1.78E-06 5.749924066 0.811635449 MGGEEKPIGAGEEK ddPTM_HeLa_Curcumin_4h_R1 2 MGGEEKPIGAGEEK 14 1 P26639;P26639-2;D6RCA5;D6R9F8;D6RDJ6;D6RJ97;D6RHV7;D6RCS6 P26639 TARS "Threonine--tRNA ligase, cytoplasmic" 0 0 ; ; 114.21 0.00036264 13308700 4848.9 3995.4 4101.7 4453.5 4828.5 5686.7 4077.8 3788.6 5147.9 4266.2 FALSE FALSE TRUE 4465.104448 4340.744573 4253.71261 4435.072597 4770.923291 4507.214318 4192.212093 4943.726699 4583.188249 4414.450132 1.01147466 0.98330357 0.963588325 1.004671582 1.080751429 1.021013758 0.949656688 1.119896375 1.03822404 1 12.10801803 -5.96724222 24.9951759 0.99997353 1.035628031 0.173088704 0.044653189 285.490704 217837.0407 0.005962194 0.010807335 1.08E-06 5.96724222 0.035654501 MGPSGGEGMEPERRDS(ph)QDGSSYR ddPTM_HeLa_Curcumin_4h_R1 1 MGPSGGEGMEPERRDSQDGSSYR 23 2 C9J9W2;Q14847;Q14847-2;Q14847-3 C9J9W2 LASP1 LIM and SH3 domain protein 1 1 0 MGPSGGEGMEPERRDS(0.977)QDGS(0.015)S(0.006)Y(0.002)R 57.248 0.007502 79237000 554.42 344.76 723.95 584.74 522.09 881.68 738.18 530.43 576.25 373.8 TRUE FALSE FALSE 510.537072 374.5595182 750.7802239 582.3205008 515.8644177 698.8096294 758.8913441 692.1556652 513.0368167 386.7895222 1.319935114 0.968380726 1.941056261 1.505522946 1.333708356 1.806692243 1.962026634 1.789489181 1.326397917 1 8.595404904 -3.039955364 0.137392646 0.794817734 3.42885545 0.476261978 0.251583297 20.29902282 0.320253047 0.79345213 9.858112025 0.000912105 3.039955364 2.634037716 MGQAPSQSLLPPAQDQPRS(ph)PVPSAFSDQSR ddPTM_HeLa_Curcumin_4h_R1 2 MGQAPSQSLLPPAQDQPRSPVPSAFSDQSR 30 1 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 MGQAPSQSLLPPAQDQPRS(0.815)PVPS(0.111)AFS(0.062)DQS(0.012)R;MGQAPSQSLLPPAQDQPRS(0.918)PVPS(0.072)AFS(0.009)DQS(0.001)R ; 76.106 2.12E-05 165184000 1327.71 1043.4 1394.47 1128.19 1115.88 1068.15 856.35 892.84 1065.15 1057.54 TRUE FALSE FALSE 1222.620353 1133.586847 1446.150285 1123.521849 1102.57386 846.6036495 880.3768763 1165.062806 948.3057099 1094.289436 1.117273284 1.03591135 1.321542763 1.026713602 1.007570596 0.773656056 0.804519213 1.064675183 0.86659496 1 10.09577866 -5.496714149 3.828473493 1.074488595 0.873289827 0.273700445 0.129414009 0.178222085 5.637587735 0.016503754 0.037071759 3.19E-06 5.496714149 -0.201198768 SSSGESLAQS(ph)PDSSK ddPTM_HeLa_Curcumin_4h_R1 1 SSSGESLAQSPDSSK 15 0 Q9H7U1-2;Q9H7U1;Q9H7U1-3 Q9H7U1-2 CCSER2 Serine-rich coiled-coil domain-containing protein 2 1 0 SSS(0.001)GES(0.146)LAQS(0.831)PDS(0.021)S(0.001)K 219.03 2.03E-14 25066000 3210.8 2918.8 2769.4 3005.4 3049.2 3695.4 2306 1048.7 3711.5 2770.9 TRUE FALSE FALSE 2956.661792 3171.088066 2872.0364 2992.964451 3012.840281 2928.932384 2370.700154 1368.443802 3304.357736 2867.188569 1.031205908 1.105992156 1.001690796 1.043867321 1.050799489 1.02153462 0.826837893 0.477277225 1.152473113 1 11.48542108 -4.328472687 1.982150347 1.026465678 0.35932383 0.924712383 0.050246268 0.082240758 0.380594409 0.004776006 0.094313421 4.69E-05 4.328472687 -0.667141847 down MGS(ph)T(ph)S(ph)RK ddPTM_HeLa_Curcumin_4h_R1 1 MGSTSRK 7 1 Q14155-6;Q14155-2;Q14155-3;Q14155;E9PDQ5 Q14155-6 ARHGEF7 Rho guanine nucleotide exchange factor 7 3 0 MGS(1)T(1)S(1)RK 40.573 0.0093968 0 1675.8 1482.6 1657.4 1417 1754.7 2358.4 1608 1317.9 1692.5 1376.3 TRUE FALSE FALSE 1543.158662 1610.749338 1718.824702 1411.136829 1733.776349 1869.241255 1653.116152 1719.721643 1506.836984 1424.126323 1.083582711 1.131043863 1.206932752 0.990878974 1.217431573 1.312552985 1.160793201 1.207562571 1.058078178 1 10.47586141 -6.832515445 0.262401905 0.976570262 1.269393562 0.440938354 0.073625762 1.272117872 0.264760709 0.086695074 0.141867052 1.47E-07 6.832515445 0.2928233 MGSDEFDISPR ddPTM_HeLa_Curcumin_4h_R1 1 MGSDEFDISPR 11 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 0 0 124.08 0.019193 86162000 1483.7 1050.5 1438.2 1562 1542.5 1817.5 1181 1423.9 2219.5 1359.4 FALSE FALSE TRUE 1366.263579 1141.300539 1491.500957 1555.536858 1524.106695 1440.530013 1214.135682 1858.040555 1976.026403 1406.639049 0.971296496 0.811367024 1.060329555 1.105853601 1.083509445 1.024093575 0.863146578 1.320907845 1.404785687 1 10.45803646 -6.5693182 24.99987473 0.971169855 1.066474104 0 0.18002958 177.6738807 95646.94268 0.017194308 0.024316428 2.70E-07 6.5693182 0.095304249 SDSPVPT(ph)APTSGGPKPSTASAVPELATDPELEKK ddPTM_HeLa_Curcumin_4h_R1 1 SDSPVPTAPTSGGPKPSTASAVPELATDPELEKK 34 2 Q86U44;B4E349;F5H6D8;B4DTN4 Q86U44 METTL3 N6-adenosine-methyltransferase 70 kDa subunit 1 0 S(0.05)DS(0.185)PVPT(0.399)APT(0.082)S(0.078)GGPKPS(0.069)T(0.069)AS(0.069)AVPELAT(0.001)DPELEKK 44.615 0.0088601 143320000 4057 3491.5 3871.5 3612.3 3396.9 3078.5 2446 700.25 3751.6 2946.3 TRUE FALSE FALSE 3735.884169 3793.289702 4014.981196 3597.35326 3356.394186 2439.984398 2514.628177 913.7530014 3340.058866 3048.683706 1.225408907 1.24423852 1.316955638 1.179969327 1.100932242 0.800340289 0.824824226 0.299720499 1.095574087 1 11.57397077 -4.32772109 1.013492328 1.14153578 4.62E-13 0.855833343 0.108913048 0.576599751 0.490634988 0.020475511 0.693319508 4.70E-05 4.32772109 -1.14153578 down MGSS(ph)PLEVPKPR ddPTM_HeLa_Curcumin_4h_R1 1 MGSSPLEVPKPR 12 1 Q8NCE2-2;Q8NCE2 Q8NCE2-2 MTMR14 Myotubularin-related protein 14 1 0 MGS(0.072)S(0.928)PLEVPKPR 151.26 0.0044963 12843000 2133.9 1381.3 1453.6 1627.8 1675.5 1921.4 1071.8 982.02 1975.6 1608.3 TRUE FALSE FALSE 1964.999563 1500.693417 1507.471695 1621.064595 1655.520757 1522.879981 1101.871823 1281.433377 1758.881623 1664.188305 1.180755541 0.901756978 0.905830001 0.974087241 0.994791726 0.915088741 0.662107659 0.770005037 1.056900603 1 10.70060297 -4.805514367 0.518187815 1.073374121 0.569236494 0.579650609 0.089042053 1.375738189 0.350479143 0.023015618 0.37707659 1.56E-05 4.805514367 -0.504137627 MGSVTAMTVFFPLDTARLR ddPTM_HeLa_Curcumin_4h_R1 1 MGSVTAMTVFFPLDTARLR 19 1 B1AHN4 B1AHN4 SLC25A17 0 0 61.265 0.010911 9488500 2756.7 2023 2109.5 2408.3 2247.5 3078.2 2342.1 2278.3 2706.9 2163 FALSE FALSE TRUE 2538.504286 2197.859106 2187.679926 2398.335093 2220.70003 2439.746622 2407.813023 2972.943182 2409.959842 2238.164089 1.134190428 0.981991944 0.97744394 1.071563566 0.99219715 1.09006602 1.075798256 1.328295453 1.076757443 1 11.12810009 -4.171045297 2.429828341 1.049576393 1.437076982 0.73878219 0.050726386 0.392588437 2.24297719 0.008712261 0.346383135 6.74E-05 4.171045297 0.387500589 LYEVAIDGKEEDLGS(ph)PTGELTSK ddPTM_HeLa_Curcumin_4h_R1 2 LYEVAIDGKEEDLGSPTGELTSK 23 1 Q8ND04;Q8ND04-2;Q8ND04-3 Q8ND04 SMG8 Protein SMG8 1 0 LYEVAIDGKEEDLGS(0.908)PT(0.09)GELT(0.002)SK;LYEVAIDGKEEDLGS(0.709)PT(0.282)GELT(0.008)S(0.002)K ; 70.501 0.0007254 16330900 3352.9 2589.7 2767.9 2758.4 3153.3 3933.4 3720.3 7146.4 3674.4 3103.9 TRUE FALSE FALSE 3087.514427 2813.542129 2870.480809 2746.986472 3115.698957 3117.568501 3824.681605 9325.304462 3271.327513 3211.760294 0.961315336 0.876012489 0.893740674 0.855290003 0.970090751 0.970672845 1.190836568 2.903487063 1.018546595 1 11.64914851 -4.251031623 3.222564504 0.958382638 3.207555401 0.991835205 0.053011892 0.024373666 0.388918173 0.008504347 0.138503898 5.61E-05 4.251031623 2.249172763 up MGWGGGAAEAPTRS(ph)T(ph)RR ddPTM_HeLa_Curcumin_4h_R1 1 MGWGGGAAEAPTRSTRR 17 2 Q9NUG4-3 Q9NUG4-3 2 0 MGWGGGAAEAPT(0.062)RS(0.971)T(0.967)RR 51.166 0.018127 13512000 4682.2 4385.9 4921.1 4713.9 3864.5 3655 3981.4 3377.8 3523.4 3972.8 TRUE FALSE FALSE 4311.598929 4764.997653 5103.480295 4694.395131 3818.418361 2896.9118 4093.107369 4407.675671 3136.891835 4110.854504 1.048832773 1.159125833 1.241464588 1.141951175 0.928862444 0.704698207 0.99568286 1.07220425 0.763075373 1 12.0052226 -5.662850434 7.833599113 1.060452498 0.912953077 0.163620101 0.147316606 0.27196268 19.1652497 0.018154049 0.036380252 2.17E-06 5.662850434 -0.147499421 MHAPPINMES(ph)VHMK ddPTM_HeLa_Curcumin_4h_R1 1 MHAPPINMESVHMK 14 0 B0YIW6;P48444;P48444-2 B0YIW6 ARCN1 Coatomer subunit delta 1 0 MHAPPINMES(1)VHMK 41.092 0.0096986 0 954.55 807.87 858.74 951.86 791.14 1081.3 726.72 579.88 1005.6 1043.9 TRUE FALSE FALSE 878.9963603 877.698683 890.5656598 947.9214555 781.7061722 857.0261912 747.1098073 756.6827426 895.2881959 1080.175447 0.813753324 0.812551966 0.824463898 0.87756249 0.723684448 0.793413879 0.69165598 0.700518369 0.828835906 1 10.07704995 -13.52287875 0.087545091 1.769527761 0.56531015 0.429311702 0.065359095 43.58857308 0.289996435 6.350702163 0.578503618 3.00E-14 13.52287875 -1.204217611 MHDGELEEQEEDDEKS(ph)DSEGGDLDK ddPTM_HeLa_Curcumin_4h_R1 1 MHDGELEEQEEDDEKSDSEGGDLDK 25 1 Q9NU22 Q9NU22 MDN1 Midasin 1 0 MHDGELEEQEEDDEKS(0.776)DS(0.224)EGGDLDK 80.702 5.62E-05 5832700 1380.3 1321.8 1629 1418.8 1951.7 1906.2 1161.7 1071.7 1463.1 1771.1 TRUE FALSE FALSE 1271.047799 1436.050502 1689.372173 1412.929382 1928.427252 1510.832633 1194.294175 1398.456397 1302.60159 1832.645593 0.693558975 0.783594224 0.921821535 0.770977971 1.052264147 0.824399785 0.651677651 0.763080653 0.710776593 1 10.8397121 -9.545611518 1.321806796 0.99961881 0.798145971 0 0.138993337 0.445514183 1.398558927 0.079648643 0.019050955 2.85E-10 9.545611518 -0.201472839 MIDQVFGVLES(ph)PELSR ddPTM_HeLa_Curcumin_4h_R1 1 MIDQVFGVLESPELSR 16 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 0 MIDQVFGVLES(0.977)PELS(0.023)R 93.342 0.0054076 3519900 1772.5 1686.6 1716.6 1654.5 1831.7 2310.7 1857.7 981.12 2102.2 1931.7 TRUE FALSE FALSE 1632.204755 1832.382189 1780.218706 1647.654117 1809.858174 1831.434773 1909.822062 1280.258971 1871.593919 1998.826431 0.816581535 0.916729017 0.890631962 0.824310751 0.905460397 0.916255031 0.955471687 0.640505324 0.936346393 1 10.96493749 -9.435140821 1.069857881 1.002998113 0.862322877 0.195202877 0.085661056 0.552052727 1.090821006 0.060443241 0.013878047 3.67E-10 9.435140821 -0.140675236 MIFVGIK ddPTM_HeLa_Curcumin_4h_R1 1 MIFVGIK 7 0 C9JFR7;P99999 C9JFR7 CYCS Cytochrome c 0 0 109.94 0.013934 568780 595.74 678.69 920.94 826.07 1392.6 741.51 781.08 1029.2 545.59 733.84 FALSE FALSE TRUE 548.5865504 737.3529394 955.0708465 822.6519412 1375.994155 587.7124675 802.9950026 1342.998342 485.740142 759.3408854 0.722450958 0.971043379 1.257762969 1.083376329 1.812090171 0.773977115 1.057489486 1.768636943 0.639686538 1 9.568603879 -6.823495553 3.347659768 0.867767455 1.275902112 0.346857434 0.309618041 0.231926233 5.282337864 0.048355421 0.065923605 1.50E-07 6.823495553 0.408134657 MIPLEKPGSGGS(ph)SPGATSGSGR ddPTM_HeLa_Curcumin_4h_R1 1 MIPLEKPGSGGSSPGATSGSGR 22 1 Q9UEE5 Q9UEE5 STK17A Serine/threonine-protein kinase 17A 1 0 MIPLEKPGS(0.08)GGS(0.289)S(0.289)PGAT(0.092)S(0.112)GS(0.137)GR 53.209 0.0082845 20714000 783.4 672.72 697.42 544.6 628.52 824.99 528.95 503.58 477.19 835.98 TRUE FALSE FALSE 721.3930634 730.8669192 723.2669987 542.3465895 621.0253095 653.8777744 543.7909134 657.1192238 424.8434509 865.0302428 0.833951263 0.844903314 0.836117586 0.626968356 0.717923234 0.755901635 0.628638037 0.759648844 0.491131327 1 9.756606762 -7.775771583 0.310719459 1.034211429 0.663677953 0 0.167380304 0.485615481 0.144562384 0.070965259 0.050189148 1.68E-08 7.775771583 -0.370533476 MIQAIDGINAQKQWLKSEDIQRIS(ph)LLFY(ph)NK ddPTM_HeLa_Curcumin_4h_R1 1 MIQAIDGINAQKQWLKSEDIQRISLLFYNK 30 3 Q08462-2;Q08462 Q08462-2 ADCY2 Adenylate cyclase type 2 2 0 MIQAIDGINAQKQWLKS(0.058)EDIQRIS(0.954)LLFY(0.988)NK 45.269 0.010669 38961000 1998.1 1987.3 1946.5 2008.6 2402 2360.4 2185.2 2288.7 2106.9 1674.7 TRUE FALSE FALSE 1839.948277 2159.073357 2018.639002 2000.288945 2373.357719 1870.826433 2246.510831 2986.514094 1875.778341 1732.8957 1.061776699 1.245933818 1.164893537 1.154304293 1.369590633 1.079595519 1.296391254 1.723424032 1.082453111 1 10.75896911 -1 0.325653803 1.028479565 6.727628914 0.658025976 0.11720453 21.23191163 0.270073371 0.037854562 73.50345245 0.1 1 5.699149349 MIS(ph)TPS(ph)PKK ddPTM_HeLa_Curcumin_4h_R1 1 MISTPSPKK 9 1 Q53F19;Q53F19-2 Q53F19 C17orf85 Uncharacterized protein C17orf85 2 0 MIS(0.725)T(0.288)PS(0.987)PKK 99.752 0.020372 26153000 3487.9 2393.6 2859.3 2837.5 2673.3 3704.2 2566.6 1257.1 3021.2 2904.3 TRUE FALSE FALSE 3211.829035 2600.492118 2965.268173 2825.759177 2641.422643 2935.907165 2638.611888 1640.384003 2689.781919 3005.224209 1.068748556 0.865323829 0.986704474 0.940282315 0.878943619 0.976934485 0.87800833 0.545844133 0.895035356 1 11.55325691 -3.891852904 1.07773451 1.003843574 1.15E-42 0.700039162 0.073681168 1.217791888 0.658247561 0.011129245 1.685413413 0.000128276 3.891852904 -1.003843574 MISDAIPELK ddPTM_HeLa_Curcumin_4h_R1 1 MISDAIPELK 10 0 P40926;P40926-2;G3XAL0 P40926 MDH2 "Malate dehydrogenase, mitochondrial;Malate dehydrogenase" 0 0 111.65 8.92E-05 0 1128.9 742.57 984.77 1061.2 928.52 1272.3 1063.4 680.04 1218.7 743.17 FALSE FALSE TRUE 1039.546374 806.754442 1021.266442 1056.809036 917.4480054 1008.410638 1093.236142 887.3810655 1085.011659 768.9951022 1.351824441 1.049102185 1.328053247 1.374272778 1.193047918 1.31133558 1.421642529 1.153948917 1.410947425 1 9.586830599 -9.44645945 0.844024863 0.973427085 1.282244022 0 0.166544369 0.511147777 0.5553667 0.110580978 0.019635122 3.58E-10 9.44645945 0.308816937 MISEVDREGT(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 MISEVDREGTGK 12 1 Q12798 Q12798 CETN1 Centrin-1 1 0 MISEVDREGT(1)GK 112.11 0.0074742 53637000 1085 867.14 1205.5 1324.9 1271.6 1380.6 1120.4 1007.3 1009.1 1004 TRUE FALSE FALSE 999.1211051 942.0917177 1250.17689 1319.417915 1256.437001 1094.247997 1151.835409 1314.421133 898.4042546 1038.888925 0.961720816 0.906826221 1.203378783 1.270027895 1.209404557 1.053286806 1.108718536 1.265218159 0.864774119 1 10.0208257 -6.753478841 24.99993556 0.975786332 1.180524662 0.721860455 0.074665355 77.97772912 244886.8454 0.010958518 0.015339258 1.76E-07 6.753478841 0.204738329 MISTPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 MISTPSPK 8 0 Q53F19;Q53F19-2 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 0 MIS(0.002)T(0.011)PS(0.988)PK 93.442 0.018891 143620000 7897.7 6012.8 6451.4 6662.2 7165.6 7909.1 7135.5 7336.2 7257.4 6553.6 TRUE FALSE FALSE 7272.588711 6532.519639 6690.494559 6634.633582 7080.1549 6268.663506 7335.702926 9572.973608 6461.281377 6781.337112 1.072441702 0.963308494 0.986604035 0.978366578 1.04406473 0.924399333 1.081748747 1.41166461 0.952803447 1 12.72735405 -4.281710463 3.632758911 1.016863797 1.447831552 0.872550392 0.047364334 0.065364827 1.570037942 0.00659938 0.073688457 5.23E-05 4.281710463 0.430967755 MIYAS(ph)SKDAIK ddPTM_HeLa_Curcumin_4h_R1 1 MIYASSKDAIK 11 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;P60981;F6RFD5;P60981-2;Q9Y281;Q9Y281-3 P23528;P60981;Q9Y281 CFL1;DSTN;CFL2 Cofilin-1;Destrin;Cofilin-2 1 0 MIYAS(0.936)S(0.064)KDAIK 141.38 0.012213 21620000 1235.8 1394.2 847.82 1293 1012.5 1364.8 1013.4 845.73 1605 1451.8 TRUE FALSE FALSE 1137.985126 1514.708436 879.240955 1287.649909 1000.426599 1081.725096 1041.833277 1103.589184 1428.935516 1502.249942 0.757520499 1.008293223 0.585282735 0.857147584 0.665952163 0.720069987 0.693515272 0.734624215 0.951196918 1 10.55290915 -13.52287875 0.155371952 1.979288701 0.662943289 0.462465951 0.102988813 37.95513141 0.397482911 11.28852849 0.19998525 3.00E-14 13.52287875 -1.316345413 MK(ac)FNPFVTSDR ddPTM_HeLa_Curcumin_4h_R1 1 MKFNPFVTSDR 11 1 J3QRI7;J3QQQ9;J3QQV1;E5RIT6;Q9UNX3;P61254;E5RHH1;J3KSS0 J3QRI7 RPL26;RPL26L1 60S ribosomal protein L26-like 1;60S ribosomal protein L26 0 1 MK(1)FNPFVTSDR 127.51 0.0011017 1394800 563.05 408.72 328.88 275.28 285.88 540.07 329.8 333.39 345.5 346.15 FALSE TRUE FALSE 518.4839984 444.0479356 341.0685821 274.1409643 282.4710677 428.0533942 339.0533004 435.0390763 307.5995144 358.1786867 1.447556813 1.239738577 0.952230255 0.765374866 0.788631703 1.195083376 0.946603784 1.21458672 0.858787878 1 8.484535683 -6.760725801 24.96672224 1.219380969 0.967419334 0.073298268 0.204207656 20.71393177 724722.3894 0.034277495 0.046852632 1.73E-07 6.760725801 -0.251961635 MKDTDSEEEIREAFR ddPTM_HeLa_Curcumin_4h_R1 1 MKDTDSEEEIREAFR 15 2 P0DP25;P0DP24;P0DP23;E7EMB3;A0A590UJC0;G3V226;G3V361;A0A590UJI2;Q96HY3 P0DP25 CALM2;CALM1 0 0 49.356 0.019558 171710000 4889.2 2912.7 3849.3 4779.7 4165 4682.5 3761 3802.5 4784.5 3465.9 FALSE FALSE TRUE 4502.214661 3164.460809 3991.958444 4759.922868 4115.335095 3711.296717 3866.523538 4961.864745 4259.65232 3586.339767 1.25537873 0.882365034 1.113101018 1.32723701 1.147502848 1.034842474 1.078125272 1.383545639 1.18774366 1 11.80829646 -6.492667 24.66060996 1.100937565 1.180728416 0.126339805 0.135964466 1426.169163 1164123.788 0.023041733 0.035165183 3.22E-07 6.492667 0.079790851 MKEIAEAYLGK ddPTM_HeLa_Curcumin_4h_R1 1 MKEIAEAYLGK 11 1 P11142;E9PKE3;P11142-2;E9PN89;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PPY6;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 156.14 0.00036381 13337000 4642.6 3461.3 4022 3595 3634.2 5570.1 4124.4 3646.3 4554.6 4337.9 FALSE FALSE TRUE 4275.133311 3760.479349 4171.058858 3580.124843 3590.864539 4414.798472 4240.119564 4758.040084 4054.971775 4488.641702 0.95243363 0.837776681 0.929247451 0.797596485 0.799989123 0.98354887 0.944633108 1.060017796 0.903385043 1 12.13206322 -7.679196004 2.237207219 0.983338053 0.904333075 0.017532432 0.081857471 0.37910649 3.972402062 0.015794856 0.016043402 2.09E-08 7.679196004 -0.079004978 LSAS(ph)PAQEK ddPTM_HeLa_Curcumin_4h_R1 1 LSASPAQEK 9 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 0 LS(0.19)AS(0.81)PAQEK 98.898 0.013776 7341500 3804 3268.4 2993.8 3759.5 4022.6 3997.4 2452.4 727.06 4003.6 3132.2 TRUE FALSE FALSE 3502.909386 3550.905932 3104.752862 3743.944185 3974.633122 3168.29418 2521.207744 948.737247 3564.415097 3241.043717 1.08079671 1.095605688 0.957948467 1.155166209 1.22634357 0.97755367 0.77789995 0.292725841 1.099773841 1 11.66224277 -4.327522269 1.833455623 1.057553622 0.111029661 0.90934038 0.076259501 0.16238565 0.6113138 0.011609917 0.251182065 4.70E-05 4.327522269 -0.946523961 down MKETIQGTGSWGPEPPGPGIPPAYSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 MKETIQGTGSWGPEPPGPGIPPAYSSPR 28 1 Q9H4L4 Q9H4L4 SENP3 Sentrin-specific protease 3 1 0 MKETIQGTGSWGPEPPGPGIPPAY(0.001)S(0.084)S(0.916)PR 130.58 1.97E-10 25359000 1124.3 773.26 867.05 766.1 907.87 992.42 1001.3 460.3 1131.2 699.14 TRUE FALSE FALSE 1035.310469 840.0971488 899.1836357 762.9300812 897.0442432 786.5809051 1029.393783 600.643351 1007.11019 723.435063 1.431103525 1.16126131 1.242936211 1.05459373 1.239978941 1.087286123 1.422924926 0.830265744 1.392122447 1 9.498719713 -6.328059519 24.98519685 1.207584475 1.14751623 0.072977064 0.18105563 787.604494 295381.7368 0.030894458 0.047192075 4.70E-07 6.328059519 -0.060068245 MKLNISFPATGCQK ddPTM_HeLa_Curcumin_4h_R1 4 MKLNISFPATGCQK 14 1 P62753;A2A3R7 P62753 RPS6 40S ribosomal protein S6 0 0 ;;; ;;; 109.84 0.00082919 4911040 5371.22 3091.05 3028.22 3002.98 2374.34 6284.6 3520.38 4157.9 6257.7 6039.5 FALSE FALSE TRUE 4946.082269 3358.226589 3140.448497 2990.554464 2346.027546 4981.103118 3619.152388 5425.624569 5571.245966 6249.372175 0.791452666 0.537370234 0.502522239 0.478536784 0.375402117 0.797056565 0.579122556 0.868187142 0.891488906 1 12.60949555 -7.748380338 1.238438211 0.943466179 0.583621598 0.47991533 0.14495431 0.226629519 0.723705586 0.03401249 0.032236191 1.78E-08 7.748380338 -0.359844581 MKPLVVFVLGGPGAGK ddPTM_HeLa_Curcumin_4h_R1 1 MKPLVVFVLGGPGAGK 16 1 P30085-2;P30085 P30085-2 CMPK1 UMP-CMP kinase 0 0 135.91 0.00035516 909860 1792.4 1392.4 1696.6 1224.4 1323.5 6330.1 3900.2 3123 1742 2039.2 FALSE FALSE TRUE 1650.529649 1512.752852 1759.477488 1219.333757 1307.718127 5017.165905 4009.629115 4075.188323 1550.906958 2110.062048 0.782218537 0.716923397 0.833851066 0.577866304 0.619753399 2.377733825 1.900242279 1.93131208 0.73500538 1 11.04306971 -5.264559917 24.99982176 0.835649161 2.05281071 0.920448909 0.176287172 58.23443138 466540.4708 0.027514072 0.064054562 5.44E-06 5.264559917 1.217161548 NMAPGAVCSPGES(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 NMAPGAVCSPGESK 14 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 NMAPGAVCS(0.086)PGES(0.914)K 130.21 0.0012652 17505000 3240.7 2397.8 2491.6 2956.7 3341.6 3631.3 3324.2 7158.2 2608.5 2287.2 TRUE FALSE FALSE 2984.195175 2605.055148 2583.940888 2944.465959 3301.753602 2878.127447 3417.468105 9340.702228 2322.354076 2366.68003 1.260920419 1.100721312 1.091799844 1.244133521 1.395099279 1.216103322 1.443992455 3.946753304 0.98127083 1 11.20864895 -4.250956897 3.401214632 1.157097346 4.340782612 0.97966824 0.11963001 0.035092084 0.663944681 0.019103959 0.292426495 5.61E-05 4.250956897 3.183685267 up MLAEDELR ddPTM_HeLa_Curcumin_4h_R1 2 MLAEDELR 8 0 F5H423;P84077;P61204;P61204-2 F5H423 ARF1;ARF3 ADP-ribosylation factor 1;ADP-ribosylation factor 3 0 0 ; ; 148.04 0.018381 28083000 10745.9 10433.5 10960.5 9575 12161.6 12789.7 10719.2 11033.4 9996.8 9625.8 FALSE FALSE TRUE 9895.350676 11335.32525 11366.70577 9535.381187 12016.58086 10136.97205 11019.9519 14397.43287 8900.176051 9960.295834 0.993479596 1.138051062 1.141201623 0.957339154 1.206448188 1.017738049 1.106388012 1.445482454 0.893565432 1 13.28197288 -1.242500506 0.97184413 1.024719114 199.9994027 0.629051406 0.091144995 347.9971824 0.892022909 0.0126578 153558.9252 0.057213629 1.242500506 198.9746836 MLAES(ph)DES(ph)GDEESVSQTDKTELQNTLR ddPTM_HeLa_Curcumin_4h_R1 1 MLAESDESGDEESVSQTDKTELQNTLR 27 1 P22059 P22059 OSBP Oxysterol-binding protein 1 2 0 MLAES(0.988)DES(0.973)GDEES(0.032)VS(0.007)QT(0.001)DKTELQNTLR 75.177 0.00036857 44419000 5717.6 3780.1 3762.3 4335.9 3954.2 4788.3 3817.7 3008.7 4849.6 4004.2 TRUE FALSE FALSE 5265.045927 4106.835 3901.734148 4317.959195 3907.048748 3795.152605 3924.814387 3926.03878 4317.611013 4143.345652 1.270723316 0.991188123 0.941686858 1.042143127 0.942969541 0.915963312 0.947257293 0.947552801 1.042059093 1 12.01658046 -7.028677403 21.48600957 1.128005553 0.958080248 0.440496729 0.073284391 96.39647584 72223.18408 0.017108531 0.02099272 9.36E-08 7.028677403 -0.169925305 MLAESDES(ph)GDEES(ph)VSQTDKTELQNTLR ddPTM_HeLa_Curcumin_4h_R1 1 MLAESDESGDEESVSQTDKTELQNTLR 27 1 P22059 P22059 OSBP Oxysterol-binding protein 1 2 0 MLAES(0.033)DES(0.984)GDEES(0.978)VS(0.005)QTDKTELQNTLR 88.684 1.17E-05 32594000 3354.7 2478.7 2428.8 2940.3 2488.5 2796.4 2073.5 1690.2 3339.6 2508.4 TRUE FALSE FALSE 3089.171955 2692.947783 2518.813465 2928.133818 2458.826263 2216.395118 2131.676829 2205.534199 2973.254235 2595.566713 1.190172435 1.03751823 0.970429098 1.128128899 0.94731769 0.853915681 0.82127607 0.84973127 1.145512546 1 11.34183385 -5.504038593 2.659650404 1.080168194 0.838311682 0.735288752 0.06392329 0.134397749 1.893324381 0.012060937 0.028690773 3.13E-06 5.504038593 -0.241856512 MLAESDES(ph)GDEESVSQTDKTELQNTLR ddPTM_HeLa_Curcumin_4h_R1 2 MLAESDESGDEESVSQTDKTELQNTLR 27 1 P22059 P22059 OSBP Oxysterol-binding protein 1 1 0 MLAES(0.064)DES(0.918)GDEES(0.014)VS(0.003)QTDKTELQNTLR;MLAES(0.093)DES(0.846)GDEES(0.061)VSQTDKTELQNTLR ; 119.28 2.08E-08 42330000 3035.9 2178.27 2275.3 3299.5 2573.3 3046.5 1803.02 2466.01 3452.1 2448.65 TRUE FALSE FALSE 2795.605312 2366.549953 2359.62462 3285.847543 2542.615078 2414.621559 1853.607889 3217.885097 3073.413267 2533.740405 1.103351119 0.934014372 0.931281127 1.296836699 1.003502598 0.952986957 0.731569771 1.270013728 1.212994536 1 11.30705301 -5.525217975 24.99665805 1.05024702 0.962647527 0.046553231 0.163788028 162.5398688 1736872.627 0.021148778 0.042516551 2.98E-06 5.525217975 -0.087599493 MLAKDELMTILEK ddPTM_HeLa_Curcumin_4h_R1 1 MLAKDELMTILEK 13 1 U3KQL3;Q9UBD5-3;Q9UBD5;Q9UBD5-2 U3KQL3 ORC3 Origin recognition complex subunit 3 0 0 36 0.019464 2815600 1979.2 1720.6 2127.8 2037.9 2013.9 1768.8 2021.8 1807.1 1665.1 1700.6 FALSE FALSE TRUE 1822.544232 1869.320997 2206.65814 2029.46771 1989.885558 1401.930942 2078.526267 2358.076471 1482.442696 1759.695723 1.035715554 1.062297858 1.253999831 1.153306042 1.130812294 0.796689407 1.181185042 1.34004785 0.842442631 1 10.78111027 -1 0.137405474 0.967825162 1.71767236 0.232657236 0.141645496 112.7792371 1.029440159 0.394539386 16.61557046 0.1 1 0.749847198 MLAQSALSPYLSS(ph)PVSSYQR ddPTM_HeLa_Curcumin_4h_R1 1 MLAQSALSPYLSSPVSSYQR 20 0 Q15434;F5H5C8;F8VV01 Q15434 RBMS2 "RNA-binding motif, single-stranded-interacting protein 2" 1 0 MLAQS(0.001)ALS(0.135)PY(0.001)LS(0.225)S(0.615)PVS(0.017)S(0.005)YQR 82.265 0.0023809 7262700 529.23 445.23 474.24 416.39 659.43 1657 1084.1 542.3 570.83 555.58 TRUE FALSE FALSE 487.3408871 483.7136973 491.8157516 414.6670885 651.5667279 1313.319522 1114.516928 707.6447736 508.2113771 574.8863636 0.847716902 0.841407499 0.855500813 0.721302704 1.133383516 2.28448543 1.938673447 1.230929829 0.884020581 1 9.167133 -5.438018695 5.791597568 0.900942581 1.824297015 0.743779576 0.251089461 0.083276363 4.46454955 0.034673033 0.078129876 3.65E-06 5.438018695 0.923354434 MLDMGFEPQIR ddPTM_HeLa_Curcumin_4h_R1 1 MLDMGFEPQIR 11 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2;P17844-2;P17844;J3KTA4;J3KRZ1;J3QSF1;A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8Y5G6;A0A2R8YFR4;A0A0D9SFB3;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;A0A0D9SF53;A0A2R8YF78;F6S8Q4;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;O15523-2;O15523;A0A2R8YDH3 A0A1X7SBZ2;P17844-2;A0A2R8YCW1 DDX17;DDX5;DDX3X;DDX3Y Probable ATP-dependent RNA helicase DDX17;Probable ATP-dependent RNA helicase DDX5;ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y 0 0 124.08 0.019193 28489000 1537.2 1201.6 1411.1 1415.8 1326.2 1871.5 1417.8 1298.3 1565.4 1402.8 FALSE FALSE TRUE 1415.528998 1305.46095 1463.396607 1409.941795 1310.385931 1483.329804 1457.579652 1694.145693 1393.679536 1451.547196 0.975186341 0.899358253 1.008163298 0.971337204 0.902751171 1.021895677 1.00415588 1.167130975 0.960133808 1 10.50337577 -4.020426768 1.683195275 0.977204209 1.343803146 0.696391969 0.039079058 0.866725685 1.425067085 0.005540559 0.620669843 9.54E-05 4.020426768 0.366598937 MLEDRDLFVMR ddPTM_HeLa_Curcumin_4h_R1 2 MLEDRDLFVMR 11 1 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 ; ; 139.15 0.0012716 16535300 4770.2 3956.9 4485.2 4660.7 4200.5 6070.6 4228.3 4448.8 5282.3 5348.6 FALSE FALSE TRUE 4392.633637 4298.916804 4651.425458 4641.415258 4150.411781 4811.48913 4346.934718 5805.21864 4702.844906 5534.463452 0.793687351 0.776754033 0.840447407 0.838638704 0.749921256 0.86936867 0.785430197 1.048921669 0.849738181 1 12.43422774 -9.31166016 1.011918956 1.001006581 0.830397436 0.029536491 0.090880585 0.420368559 0.763919845 0.051760324 0.013461857 4.88E-10 9.31166016 -0.170609145 MLEEDLLALK ddPTM_HeLa_Curcumin_4h_R1 1 MLEEDLLALK 10 0 B9A058 B9A058 HIBCH 0 0 91.318 0.019793 4358700 241.05 529.74 336.89 398.47 2595.7 3686.5 580.88 878 1581.7 536.87 FALSE FALSE TRUE 221.9706381 575.5283651 349.3754398 396.8212367 2564.747973 2921.878345 597.1779294 1145.698158 1408.191467 555.5261925 0.399568267 1.036005814 0.628909032 0.71431598 4.616790364 5.259659011 1.074977089 2.062365688 2.534878618 1 9.117711125 -5.782612677 24.88531959 0.729058679 3.241143537 0.413615492 1.248840602 131.1158283 154102.2961 0.169522089 0.307506442 1.65E-06 5.782612677 2.512084858 MLGEDS(ph)DEEEEMDTSER ddPTM_HeLa_Curcumin_4h_R1 7 MLGEDSDEEEEMDTSER 17 0 A0A087X0M4;Q9BWU0;A0A087WWF4;H7C256 A0A087X0M4 SLC4A1AP Kanadaptin 1 0 MLGEDS(0.959)DEEEEMDT(0.04)S(0.001)ER;MLGEDS(1)DEEEEMDTSER;MLGEDS(1)DEEEEMDTSER;MLGEDS(0.997)DEEEEMDT(0.002)SER;MLGEDS(1)DEEEEMDTSER;MLGEDS(1)DEEEEMDTSER;MLGEDS(1)DEEEEMDTSER ;;;;;; 257.37 1.07E-40 292108000 11769.59 9861.02 10415.79 10733.86 11144.96 12645.76 9901.05 9705.82 11691.75 9938 TRUE FALSE FALSE 10838.01453 10713.36263 10801.80834 10689.44613 11012.06363 10022.88683 10178.84682 12665.07984 10409.19428 10283.34476 1.053938654 1.041816926 1.050417796 1.039491175 1.070863993 0.974671866 0.989838137 1.231610933 1.012238189 1 13.32802197 MLGEDS(ph)DEEEEMDTSERK ddPTM_HeLa_Curcumin_4h_R1 2 MLGEDSDEEEEMDTSERK 18 1 A0A087X0M4;Q9BWU0;A0A087WWF4;H7C256 A0A087X0M4 SLC4A1AP Kanadaptin 1 0 MLGEDS(1)DEEEEMDTSERK;MLGEDS(1)DEEEEMDTSERK ; 152.01 3.13E-05 53198000 3452.1 2940 2917 3525.6 3364.8 2861.87 2491 2340.2 3824.4 3028.9 TRUE FALSE FALSE 3178.862642 3194.1205 3025.106586 3511.012001 3324.676958 2268.285902 2560.890756 3053.716207 3404.872888 3134.15405 1.014264963 1.019133217 0.965206731 1.120242319 1.060789261 0.723731465 0.817091539 0.974335071 1.086377005 1 11.61386038 -5.27528475 24.99065713 1.016489737 0.836256571 0.604493806 0.072539615 377.0686449 680602.2265 0.009568593 0.021500046 5.31E-06 5.27528475 -0.180233165 MLGEDSDEEEEMDT(ph)SER ddPTM_HeLa_Curcumin_4h_R1 1 MLGEDSDEEEEMDTSER 17 0 A0A087X0M4;Q9BWU0;A0A087WWF4;H7C256 A0A087X0M4 SLC4A1AP Kanadaptin 1 0 MLGEDS(0.104)DEEEEMDT(0.882)S(0.014)ER 129.82 0.0090743 22654000 1129.5 877.66 867.88 888.62 985.09 1218.8 846.87 812.97 974.4 919.03 TRUE FALSE FALSE 1040.098883 953.5210196 900.0443963 884.9431259 973.3434451 966.0071413 870.630893 1060.840811 867.5107578 950.9662241 1.093728522 1.002686526 0.946452538 0.930572615 1.023531037 1.015816458 0.915522414 1.115539946 0.912241398 1 9.893250291 -7.017316841 23.83907736 1.044468423 0.986536941 0 0.071089691 537.5289004 739985.3025 0.009878002 0.012256526 9.61E-08 7.017316841 -0.057931482 MLITILGTVKPNANR ddPTM_HeLa_Curcumin_4h_R1 3 MLITILGTVKPNANR 15 1 G3V3R6;P17931 G3V3R6 LGALS3 Galectin;Galectin-3 0 0 ;; ;; 135.94 0.00021924 13616800 1987.01 1075.41 1616.19 1415.63 1908.47 3556.7 2117.98 2871.92 2156.99 1552.88 FALSE FALSE TRUE 1829.736062 1168.363648 1676.087423 1409.772498 1885.712742 2819.000328 2177.404819 3747.555187 1920.373594 1606.842464 1.138715277 0.727117732 1.043093807 0.877355764 1.173551722 1.75437256 1.355082945 2.332248039 1.195122506 1 10.65001278 -2.506182525 0.611223571 1.024143446 12.40758397 0.772959424 0.2117333 7.746171234 0.359473079 0.035318632 99.31128448 0.003117579 2.506182525 11.38344053 up MLKSQSSS(ph)AEQS(ph)FLFS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 MLKSQSSSAEQSFLFSR 17 1 Q9Y6D9-3;Q9Y6D9 Q9Y6D9-3 MAD1L1 Mitotic spindle assembly checkpoint protein MAD1 3 0 MLKS(0.012)QS(0.008)S(0.451)S(0.53)AEQS(0.999)FLFS(0.999)R 52.273 0.0093087 0 2440.8 1806.1 1914.2 2018.6 2361.2 2091.9 1780 1394.5 2059.1 2107.7 TRUE FALSE FALSE 2247.608104 1962.211236 1985.141936 2010.247568 2333.044232 1658.016359 1829.942009 1819.676631 1833.221882 2180.942418 1.030567376 0.899707952 0.910222076 0.921733445 1.069741325 0.760229314 0.839060213 0.834353358 0.840564091 1 11.09073596 -5.018612805 0.407906591 1.015625512 0.731848808 0.070637833 0.089609096 1.983737681 0.338971112 0.020977503 0.247794007 9.58E-06 5.018612805 -0.283776704 MLLVDELR ddPTM_HeLa_Curcumin_4h_R1 2 MLLVDELR 8 0 C9JPM4;P18085;C9JAK5;U3KQF2 C9JPM4 ARF4 ADP-ribosylation factor 4 0 0 ; ; 104.45 0.0061953 355250 982.74 703.05 684.09 536.56 659.27 1604.09 1214.95 980.5 632.67 682.49 FALSE FALSE TRUE 904.955092 763.8185093 709.4429772 534.3398569 651.4086358 1271.383652 1249.038227 1279.449936 563.2676839 706.2064767 1.281431312 1.081579587 1.004582938 0.756634036 0.922405355 1.800300187 1.768658697 1.811722178 0.797596316 1 9.463946242 -5.253988469 24.86169855 1.080849344 1.791070259 0.833644401 0.16249714 183.8549484 613472.6394 0.024691018 0.061600385 5.57E-06 5.253988469 0.710220916 MLNS(ph)SFEDDPFFSESILAHR ddPTM_HeLa_Curcumin_4h_R1 1 MLNSSFEDDPFFSESILAHR 20 0 A0A494C175;A0A0S2Z4A4;P58340 A0A494C175 MLF1 Myeloid leukemia factor 1 1 0 MLNS(0.574)S(0.426)FEDDPFFSESILAHR 60.86 0.009548 2132400 794.8 671.66 715.16 893.94 1047.4 748.94 689.41 443.53 875.14 805.63 TRUE FALSE FALSE 731.8907413 729.7152975 741.6644587 890.2411131 1034.910439 593.6014017 708.7529891 578.7602552 779.1393315 833.6255825 0.87796099 0.875351372 0.889685339 1.067914819 1.241457149 0.712071959 0.850205421 0.694268827 0.934639421 1 9.703255742 MLNSS(ph)FEDDPFFSESILAHR ddPTM_HeLa_Curcumin_4h_R1 1 MLNSSFEDDPFFSESILAHR 20 0 A0A494C175;A0A0S2Z4A4;P58340 A0A494C175 MLF1 Myeloid leukemia factor 1 1 0 MLNS(0.415)S(0.585)FEDDPFFSESILAHR 68.771 0.0042595 2284300 865.34 627.32 699.84 962.84 944.9 775.67 578.1 394.81 825.25 773.11 TRUE FALSE FALSE 796.8474259 681.5427455 725.776686 958.8560232 933.6326846 614.7872984 594.3199301 515.1857515 734.7221397 799.975515 0.996089769 0.851954507 0.907248625 1.198606714 1.167076576 0.768507644 0.742922651 0.6440019 0.918430784 1 9.643812034 -5.097341197 5.838513305 1.004797667 0.707565829 0.6157913 0.104849617 0.112818519 5.501248489 0.014941899 0.03908342 7.99E-06 5.097341197 -0.297231838 MLPDK(ac)DCR ddPTM_HeLa_Curcumin_4h_R1 1 MLPDKDCR 8 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 1 MLPDK(1)DCR 99.442 0.013682 15522000 4238.8 3308.2 3701.4 2457 6911.9 8211.7 6552.5 5619.6 6761.5 3191 FALSE TRUE FALSE 3903.294507 3594.146067 3838.57714 2446.833585 6829.480107 6508.500855 6736.345515 7332.990171 6019.780366 3301.887012 1.182140543 1.088512736 1.162540428 0.741040979 2.068356695 1.971145842 2.04015022 2.220848304 1.823133361 1 11.68907504 -5.749471618 24.99902967 1.073038869 2.065200263 0.725014808 0.270566545 39.78656732 83108.19595 0.019204513 0.038171578 1.78E-06 5.749471618 0.992161395 MLPDKDCR ddPTM_HeLa_Curcumin_4h_R1 3 MLPDKDCR 8 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 0 ;; ;; 111.82 0.0088732 225358000 26057.1 15068.1 22112.6 18470.6 22691.6 25755 22107.7 19002 20447.1 21379.8 FALSE FALSE TRUE 23994.65304 16370.51942 22932.11241 18394.17355 22421.01749 20413.12268 22727.98256 24795.62233 18204.10429 22122.74646 1.084614566 0.739985854 1.036585238 0.831459764 1.01348255 0.922720998 1.027358091 1.120820255 0.822868188 1 14.43324288 MLPHAPGVQMQAIPEDAIPEES(ph)GDEDEDDPDKR ddPTM_HeLa_Curcumin_4h_R1 9 MLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKR 33 1 Q13547 Q13547 HDAC1 Histone deacetylase 1 1 0 MLPHAPGVQMQAIPEDAIPEES(1)GDEDEDDPDKR;MLPHAPGVQMQAIPEDAIPEES(1)GDEDEDDPDKR;MLPHAPGVQMQAIPEDAIPEES(1)GDEDEDDPDKR;MLPHAPGVQMQAIPEDAIPEES(1)GDEDEDDPDKR;MLPHAPGVQMQAIPEDAIPEES(1)GDEDEDDPDKR;MLPHAPGVQMQAIPEDAIPEES(1)GDEDEDDPDKR;MLPHAPGVQMQAIPEDAIPEES(1)GDEDEDDPDKR;MLPHAPGVQMQAIPEDAIPEES(1)GDEDEDDPDKR;MLPHAPGVQMQAIPEDAIPEES(1)GDEDEDDPDKR ;;;;;;;; 104.89 2.87E-14 2081769000 29001.16 22323.56 25105.58 27038.59 25090.63 35250.8 23918.04 23619.22 29706.65 27087.83 TRUE FALSE FALSE 26705.68758 24253.10905 26036.01488 26926.71148 24791.44062 27939.38672 24589.11583 30820.61145 26447.90482 28029.13008 0.952783319 0.865282261 0.928891293 0.960668826 0.884488407 0.996798211 0.877270032 1.099592152 0.94358636 1 14.77463935 -8.584304985 1.07710661 0.993996903 0.941672459 0 0.066719488 0.733357941 1.721530268 0.020575644 0.011639254 2.60E-09 8.584304985 -0.052324443 MLPHAPGVQMQAIPEDAVHEDS(ph)GDEDGEDPDKR ddPTM_HeLa_Curcumin_4h_R1 4 MLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKR 33 1 Q92769-3;Q92769 Q92769-3 HDAC2 Histone deacetylase 2 1 0 MLPHAPGVQMQAIPEDAVHEDS(1)GDEDGEDPDKR;MLPHAPGVQMQAIPEDAVHEDS(1)GDEDGEDPDKR;MLPHAPGVQMQAIPEDAVHEDS(1)GDEDGEDPDKR;MLPHAPGVQMQAIPEDAVHEDS(1)GDEDGEDPDKR ;;; 72.769 5.19E-06 322898000 10113.5 9438.2 9388.3 9609.3 9143.4 11464.9 8986.3 8934.2 11244.3 9762.9 TRUE FALSE FALSE 9313.005803 10253.99595 9736.238657 9569.539263 9034.370927 9086.950504 9238.431393 11658.19645 10010.82842 10102.16005 0.921882623 1.015030043 0.963777906 0.947276545 0.89430091 0.899505696 0.914500597 1.154030068 0.990959198 1 13.30237618 -9.638341284 1.461655934 1.000019193 0.953312227 0.013308451 0.072915786 1.102307686 4.22981212 0.049864982 0.011303571 2.30E-10 9.638341284 -0.046706966 MLPSLQES(ph)MDGDEKELESSEEGGSAEER ddPTM_HeLa_Curcumin_4h_R1 1 MLPSLQESMDGDEKELESSEEGGSAEER 28 1 J3QKQ1;J9JIC5;Q9HAS0 J3QKQ1 C17orf75 Protein Njmu-R1 1 0 MLPS(0.138)LQES(0.825)MDGDEKELES(0.025)S(0.012)EEGGSAEER 53.097 0.0022656 8746400 1440.1 1092.5 1319.3 1261.3 980.33 1479.7 1281.4 545.61 1467 1260.3 TRUE FALSE FALSE 1326.114565 1186.930832 1368.194419 1256.081075 968.640205 1172.79354 1317.352635 711.9639773 1306.07377 1304.095331 1.016884681 0.910156492 1.049152149 0.963181943 0.742767942 0.899315803 1.010165901 0.545944733 1.001517097 1 10.34883362 -3.279391807 0.489708393 1.002611958 4.94E-26 0.496482074 0.10538994 6.300838812 0.502964353 0.020627137 4.523068246 0.000525543 3.279391807 -1.002611958 MLS(ph)FQQMT(ph)WRTNIR ddPTM_HeLa_Curcumin_4h_R1 1 MLSFQQMTWRTNIR 14 1 F8W1T8 F8W1T8 CLEC17A 2 0 MLS(1)FQQMT(0.823)WRT(0.177)NIR 50.467 0.0201 1792000 484.57 569.47 477.03 448.4 433.51 423.11 484.2 574.47 720.4 642.42 TRUE FALSE FALSE 446.2157732 618.6924493 494.7091514 446.5446396 428.3406764 335.3522166 497.7853488 749.6232585 641.3739224 664.7440472 0.671259525 0.930722813 0.744209976 0.671754251 0.64436933 0.504483219 0.748837618 1.127687057 0.964843424 1 9.376655143 -9.4275538 0.89432563 1.018364427 0.738722312 0.233801848 0.161861329 0.780414613 0.991818631 0.156479542 0.030304797 3.74E-10 9.4275538 -0.279642115 EGS(ph)PEPWLPLTDGR ddPTM_HeLa_Curcumin_4h_R1 2 EGSPEPWLPLTDGR 14 0 J3KSM5;Q494U1-3;Q494U1;Q494U1-2 J3KSM5 PLEKHN1 Pleckstrin homology domain-containing family N member 1 1 0 EGS(1)PEPWLPLTDGR;EGS(0.988)PEPWLPLT(0.012)DGR ; 144.88 0.00064342 6976300 3035.5 2296.1 2408.3 2618.7 2234.3 2458.4 1590.36 770.59 3329.3 2645.3 TRUE FALSE FALSE 2795.236972 2494.564653 2497.553717 2607.864513 2207.657432 1948.500128 1634.981221 1005.539344 2964.084119 2737.223978 1.021194098 0.911348385 0.912440391 0.952740636 0.806531526 0.711852645 0.597313641 0.367357349 1.082879641 1 11.41849778 -4.327218668 0.552056153 1.007992407 1.56E-21 0.960564659 0.041663145 0.384998544 0.082375332 0.00687558 0.244705845 4.71E-05 4.327218668 -1.007992407 down MLVELSK ddPTM_HeLa_Curcumin_4h_R1 1 MLVELSK 7 0 P50991-2;P50991 P50991-2 CCT4 T-complex protein 1 subunit delta 0 0 107.59 0.015477 1183900 2023.7 1816.7 2197.4 1787.3 1785 2942.2 2006.8 2008.1 2170.8 1932.1 FALSE FALSE TRUE 1863.52201 1973.727453 2278.837577 1779.904626 1763.715041 2331.954555 2063.105407 2620.360446 1932.668671 1999.240331 0.932115054 0.987238714 1.139851743 0.890290476 0.882192608 1.166420324 1.031944672 1.310678064 0.966701522 1 10.9652362 -1.000003541 0.774019756 0.973454077 70.1291566 0.55403568 0.08633536 220.8346397 0.80837262 0.013408445 26728.74378 0.099999185 1.000003541 69.15570252 MLVIEQCK ddPTM_HeLa_Curcumin_4h_R1 1 MLVIEQCK 8 0 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 0 93.429 0.019427 1791900 1598.5 1012.3 1492 982.43 1187.3 1644.8 994.54 979.69 1471.2 1323.7 FALSE FALSE TRUE 1471.977038 1099.798701 1547.294832 978.364965 1173.142223 1303.649939 1022.444116 1278.392971 1309.813041 1369.698476 1.074672319 0.802949496 1.129660914 0.71429222 0.856496698 0.951778776 0.746473865 0.933338974 0.95627838 1 10.41964262 -6.666154457 1.181095458 1.031052477 0.850202283 0.176053006 0.117242826 0.371893939 1.040422688 0.019547686 0.031142393 2.16E-07 6.666154457 -0.180850194 MLVS(ph)LKMSYK ddPTM_HeLa_Curcumin_4h_R1 2 MLVSLKMSYK 10 1 G3V2F2;G3V3R3;G3V3Y5;G3V3H8;G3V277;G3V2Y7;G3V456;G3V5U1;G3V227;G3V3P2;G3V423;G3V3X0;G3V3S7;G3V5W1;G3V4N0;G3V4N8;G3V4C7;G3V2C0;G3V339;G3V313;G3V4S4;P23381-2;P23381 G3V2F2 WARS "Tryptophan--tRNA ligase, cytoplasmic;T1-TrpRS;T2-TrpRS" 1 0 MLVS(1)LKMSYK;MLVS(1)LKMSYK ; 70.056 0.013198 49381000 4251.1 3570.9 3876.1 3969.8 4218.3 6671.4 4460.5 4849.3 4642.2 4355.1 TRUE FALSE FALSE 3914.620949 3879.552684 4019.751676 3953.374019 4167.999528 5287.676438 4585.649625 6327.829247 4132.962274 4506.439401 0.868672715 0.860890903 0.892001715 0.877272203 0.924898608 1.173360156 1.01757712 1.404174934 0.917123677 1 12.13777228 -1.000000376 0.710856816 0.923354704 64.43061158 0.789126898 0.075335894 106.7046717 0.506427074 0.013674807 10804.42065 0.099999914 1.000000376 63.50725688 MLWGSDPYPHAEPQQAT(ph)TPK ddPTM_HeLa_Curcumin_4h_R1 2 MLWGSDPYPHAEPQQATTPK 20 0 E7EPN9;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;Q9Y520-2 E7EPN9 PRRC2C Protein PRRC2C 1 0 MLWGSDPYPHAEPQQAT(0.98)T(0.02)PK;MLWGSDPYPHAEPQQAT(0.861)T(0.139)PK ; 134.83 9.91E-05 63028000 2132.08 2092.78 2098.97 2119.63 2222 3469.5 2599.9 2929.5 2605.7 1905.53 TRUE FALSE FALSE 1963.323618 2273.670578 2176.759675 2110.859533 2195.504101 2749.886591 2672.846197 3822.691064 2319.861229 1971.747026 0.995727947 1.153124893 1.103975128 1.070552918 1.113481635 1.394644726 1.355572577 1.938733019 1.176551149 1 10.94525875 -1 0.499926982 1.006691865 29.65888423 0.885854192 0.090442288 14.91013177 0.14319852 0.013552107 451.4304723 0.1 1 28.65219237 MMALVAELS(ph)MK ddPTM_HeLa_Curcumin_4h_R1 1 MMALVAELSMK 11 0 Q8IYE0-2;Q8IYE0 Q8IYE0-2 CCDC146 Coiled-coil domain-containing protein 146 1 0 MMALVAELS(1)MK 46.706 0.0093233 0 2690.9 2656.4 2696.1 2403.4 2779.7 2447.1 2165.4 866.67 2284 2310.6 TRUE FALSE FALSE 2477.912426 2886.007379 2796.019838 2393.455368 2746.553893 1939.543875 2226.155296 1130.913693 2033.450914 2390.893178 1.036396125 1.207083364 1.169445738 1.001071645 1.148756422 0.811221469 0.931097766 0.473008875 0.850498438 1 11.22333396 -4.021598139 1.135557265 1.046656541 6.29E-16 0.675254107 0.11702498 0.994754448 0.726761708 0.014947999 1.405724626 9.51E-05 4.021598139 -1.046656541 MMRLRGSGMLR ddPTM_HeLa_Curcumin_4h_R1 1 MMRLRGSGMLR 11 2 O94925-2;O94925-3;O94925 O94925-2 GLS "Glutaminase kidney isoform, mitochondrial" 0 0 63.816 0.0077443 0 865.56 1063.1 1099.5 1088.9 1007.5 677.32 759.09 778.44 1208.1 1133.4 FALSE FALSE TRUE 797.0500127 1154.989627 1140.248437 1084.39442 995.4862205 536.836197 780.3880224 1015.782773 1075.574453 1172.785566 0.679621268 0.984825923 0.972256541 0.924631452 0.848822027 0.457744547 0.665414075 0.866128304 0.917110923 1 10.19572354 -5.48469917 23.67194702 0.872177226 0.661653288 0.412306754 0.128177802 298.4794854 185061.2433 0.022248546 0.049734648 3.28E-06 5.48469917 -0.210523938 MMS(ph)MLGGLQR ddPTM_HeLa_Curcumin_4h_R1 2 MMSMLGGLQR 10 0 Q9H3Q3 Q9H3Q3 GAL3ST2 Galactose-3-O-sulfotransferase 2 1 0 MMS(1)MLGGLQR;MMS(1)MLGGLQR ; 77.533 0.0051843 4951100 3375.6 2706.3 3246.4 2803.6 3243.3 3484.5 2857.8 2733.2 3130.5 3222.5 TRUE FALSE FALSE 3108.417698 2940.220513 3366.71444 2791.999446 3204.625766 2761.775422 2937.982177 3566.540098 2787.091982 3334.481635 0.932204174 0.881762395 1.009666511 0.837311388 0.961056655 0.828247303 0.881091125 1.069593565 0.835839656 1 11.70324679 -8.817720591 0.611831024 1.003667546 0.918194334 0 0.087442185 1.227591734 0.839601517 0.05377906 0.016150152 1.52E-09 8.817720591 -0.085473212 MNEVS(ph)VIK ddPTM_HeLa_Curcumin_4h_R1 1 MNEVSVIK 8 0 P31751;P31751-2;C9JHS6;J3QLS6;M0QZK3;A0A1B0GXA2;E7EVP8;A8MX96;C9JIF6;C9J258;A0A5F9ZHJ8;A0A0A0MRF1;C9JIJ1;C9JC83;J3KSY8;J3KRI8 P31751 AKT2 RAC-beta serine/threonine-protein kinase 1 0 MNEVS(1)VIK 128.6 0.0066299 114520000 2344.3 2558.3 2290.2 2460.2 2300 2831.6 2519.6 2369.2 2761.7 2261.3 TRUE FALSE FALSE 2158.746181 2779.428052 2375.076827 2450.020344 2272.574002 2244.294241 2590.293195 3091.558174 2458.748419 2339.880007 0.922588413 1.187850678 1.015042147 1.047070934 0.971235275 0.959149288 1.107019671 1.321246459 1.050801072 1 11.19221883 -4.360299552 2.445394945 0.988793834 1.360178414 0.582424568 0.07355881 0.205162284 1.729788943 0.010800435 0.144199955 4.36E-05 4.360299552 0.37138458 MNFADEFAKLQDY(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 MNFADEFAKLQDYR 14 1 E5RFS7;E5RGE3;E5RID3 E5RFS7 FAM92A1 1 0 MNFADEFAKLQDY(1)R 103.26 0.0061341 16221000 3047.8 2202.7 2066.2 3110.9 2938.3 4070 2664.3 2508.8 2998.7 1971.3 TRUE FALSE FALSE 2806.563414 2393.091573 2142.77519 3098.02792 2903.262692 3225.836122 2739.053087 3273.721571 2669.750112 2039.802528 1.375899566 1.17319767 1.050481681 1.518788156 1.423305762 1.5814453 1.342803065 1.604920832 1.30882773 1 10.99421378 -6.250925726 24.5050368 1.172964271 1.486741324 0.613801206 0.123800183 354.4944531 826248.7309 0.023474748 0.038640983 5.61E-07 6.250925726 0.313777053 MNGVMFPGNS(ph)PSYTER ddPTM_HeLa_Curcumin_4h_R1 3 MNGVMFPGNSPSYTER 16 0 Q9NY27-2;Q9NY27-3;Q9NY27 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 0 MNGVMFPGNS(0.964)PS(0.031)YT(0.004)ER;MNGVMFPGNS(0.948)PS(0.029)Y(0.022)T(0.002)ER;MNGVMFPGNS(0.994)PS(0.006)YT(0.001)ER ;; 87.99 0.0083325 83780600 8553.3 7105.4 8297 8110.2 8058.6 9834 6127.6 5300.27 9265.2 7641.8 TRUE FALSE FALSE 7876.29728 7719.559115 8604.494119 8076.642141 7962.506458 7794.317548 6299.523964 6916.297924 8248.83074 7907.351981 0.99607268 0.976250853 1.088163792 1.02140921 1.006975088 0.985705147 0.796666694 0.874666758 1.04318497 1 12.94897893 -4.82067965 6.331133432 1.005075375 0.836088711 0.797841671 0.035838245 0.054007327 4.261577295 0.004596202 0.014292779 1.51E-05 4.82067965 -0.168986664 MNILMLT(ph)FIICGLLT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 MNILMLTFIICGLLTR 16 0 Q8N687 Q8N687 DEFB125 Beta-defensin 125 2 0 MNILMLT(1)FIICGLLT(1)R 45.879 0.0096029 0 192.48 203.56 49.452 176 0 147.45 61.105 57.882 193.48 207.67 TRUE FALSE FALSE 177.2450049 221.1548194 51.28473462 175.2717586 0 116.8672079 62.81944184 75.52995534 172.2557281 214.886517 0.82483074 1.029170291 0.238659621 0.815648004 0 0.543855471 0.292337754 0.351487643 0.801612546 1 7.747431154 -6.763770048 24.99999913 0.923361626 0.380809374 0.618754393 0.207648348 27.54595558 295473.7693 0.030272897 0.040862586 1.72E-07 6.763770048 -0.542552252 MNLIIICMAR ddPTM_HeLa_Curcumin_4h_R1 1 MNLIIICMAR 10 0 Q13472-3 Q13472-3 0 0 130.22 0.015114 8361700 3695.3 2527.1 3295.2 2813.7 3084.9 3888 3450.7 2956 3068.9 2866.6 FALSE FALSE TRUE 3402.813106 2745.531263 3417.323011 2802.057655 3048.114582 3081.584973 3547.517355 3857.270792 2732.249348 2966.214137 1.147190644 0.925601166 1.152082369 0.944657913 1.027611104 1.038894979 1.195974799 1.300401999 0.921123433 1 11.53440704 -4.572545023 2.953771805 1.052834009 1.29199019 0.5378284 0.082656228 0.159861114 2.624345558 0.010917111 0.06404098 2.68E-05 4.572545023 0.239156181 MNRGINDSKDLPEEY(ph)LS(ph)AIYNEIAGKK ddPTM_HeLa_Curcumin_4h_R1 1 MNRGINDSKDLPEEYLSAIYNEIAGKK 27 3 E5RIF2;Q9Y6D6 E5RIF2 ARFGEF1 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 2 0 MNRGINDS(0.002)KDLPEEY(0.923)LS(0.927)AIY(0.148)NEIAGKK 42.106 0.012718 20984000 4808.9 2816.8 3052.3 3775.3 4060 4569.8 2852.3 2218.4 4469.6 3101.5 TRUE FALSE FALSE 4428.270491 3060.271641 3165.420923 3759.678809 4011.587152 3621.971968 2932.327861 2894.779948 3979.296062 3209.276894 1.379834348 0.953570459 0.986334625 1.171503405 1.249997206 1.128594412 0.913703603 0.902003798 1.23993541 1 11.64803255 -4.776292455 4.861390041 1.155560652 0.903238377 0.343064556 0.126615299 0.177569879 10.83261458 0.022958882 0.079980598 1.67E-05 4.776292455 -0.252322275 MNS(ph)TGGQTPR ddPTM_HeLa_Curcumin_4h_R1 2 MNSTGGQTPR 10 0 Q96ST2-3;Q96ST2;Q96ST2-2;A0A1B0GW95 Q96ST2-3 IWS1 Protein IWS1 homolog 1 0 MNS(0.928)T(0.071)GGQTPR;MNS(0.775)T(0.221)GGQT(0.004)PR ; 98.368 0.01366 89814000 3586.1 3401.9 3618 3331 3411.1 3576.9 3347.3 6166.4 3994.6 3360.3 TRUE FALSE FALSE 3302.256401 3695.945077 3752.086263 3317.217205 3370.42486 2835.01062 3441.216229 8046.506973 3556.402374 3477.070175 0.949723829 1.062948083 1.079094201 0.954026533 0.969328973 0.815344666 0.989688461 2.31416295 1.022815818 1 11.76365647 -4.261612899 7.884733896 0.97605657 2.325735411 0.970806809 0.069270112 0.010519404 7.554719657 0.009514697 0.075422272 5.48E-05 4.261612899 1.349678841 MNSTGGQT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 MNSTGGQTPR 10 0 Q96ST2-3;Q96ST2;Q96ST2-2;A0A1B0GW95 Q96ST2-3 IWS1 Protein IWS1 homolog 1 0 MNSTGGQT(1)PR 117.86 0.014313 35238000 4082.2 4581.3 3543.8 3582.2 3809.1 5571.2 3416.3 1761.7 5026.9 4194.4 TRUE FALSE FALSE 3759.089562 4977.287158 3675.136345 3567.377806 3763.67897 4415.67032 3512.152183 2298.83422 4475.461647 4340.155088 0.866118718 1.146799379 0.84677535 0.821947081 0.867176148 1.017399201 0.809222738 0.529666377 1.031175512 1 12.08353088 -4.342106494 2.853262332 0.9351465 0.492229813 0.626071622 0.098226927 0.168911669 2.071727033 0.013388649 0.156060505 4.55E-05 4.342106494 -0.442916687 MNYMQNHQAGAPAPS(ph)LSR ddPTM_HeLa_Curcumin_4h_R1 1 MNYMQNHQAGAPAPSLSR 18 0 Q9HCK8-2;Q9HCK8;H0YJG4;A0A2R8Y840 Q9HCK8-2 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 0 MNYMQNHQAGAPAPS(0.581)LS(0.419)R 76.492 0.003707 9282700 1823.2 1530.6 1489 1537.7 1666.6 1583.7 1572.1 1029.3 1994.7 1606.3 TRUE FALSE FALSE 1678.891796 1662.898244 1544.18365 1531.337405 1646.726883 1255.222768 1616.208895 1343.128832 1775.8864 1662.118805 1.010091331 1.000468943 0.929045291 0.921316455 0.990739578 0.755194372 0.972378683 0.808082327 1.06844733 1 10.69880779 -5.925602014 0.716719544 1.006458428 0.853816465 0.493211658 0.065247566 0.470728457 0.444043071 0.010981684 0.037271852 1.19E-06 5.925602014 -0.152641963 MNYMQNHQAGAPAPSLS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 MNYMQNHQAGAPAPSLSR 18 0 Q9HCK8-2;Q9HCK8;H0YJG4;A0A2R8Y840 Q9HCK8-2 CHD8 Chromodomain-helicase-DNA-binding protein 8 1 0 MNYMQNHQAGAPAPS(0.235)LS(0.765)R 71.042 0.0057562 9091100 2235.5 2218.8 2229.9 2403.9 1995.9 2399.8 2150.9 830.3 2271.5 2471.1 TRUE FALSE FALSE 2058.557816 2410.583185 2312.542056 2393.953299 1972.100196 1902.054429 2211.248465 1083.454648 2022.322133 2556.970541 0.805076861 0.94274969 0.904407 0.936245944 0.77126434 0.743870294 0.864792312 0.423725902 0.790905527 1 11.32021982 -3.879903623 0.876568918 0.904497129 5.13E-40 0.65287391 0.090578874 1.918105963 0.695022043 0.015018139 1.948483202 0.000131855 3.879903623 -0.904497129 MPCES(ph)SPPESADTPTSTR ddPTM_HeLa_Curcumin_4h_R1 2 MPCESSPPESADTPTSTR 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 MPCES(0.903)S(0.094)PPES(0.003)ADTPTSTR;MPCES(0.613)S(0.387)PPESADTPTSTR ; 179.66 7.75E-07 18938300 5337.49 3904.08 3856.21 5408.49 4019.7 5603.15 4667.59 3346.52 6222.86 4202.01 TRUE FALSE FALSE 4915.022034 4241.531279 3999.124535 5386.111101 3971.767703 4440.993529 4798.550013 4366.858543 5540.227827 4348.029535 1.130402173 0.975506547 0.919755605 1.238747589 0.913463828 1.021380718 1.103614862 1.004330469 1.274192777 1 12.08614602 -7.242857451 24.84878661 1.061578811 1.027975449 0.064233062 0.114917157 2773.310171 3708624.453 0.015841803 0.019383153 5.72E-08 7.242857451 -0.033603362 MPCESS(ph)PPES(ph)ADTPTSTR ddPTM_HeLa_Curcumin_4h_R1 1 MPCESSPPESADTPTSTR 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 2 0 MPCES(0.28)S(0.876)PPES(0.644)ADT(0.185)PT(0.012)S(0.003)T(0.001)R 93.768 0.0019129 0 1013.5 677.6 796.23 1116.9 937.47 1264.7 1263.3 952.77 1046.7 839.78 TRUE FALSE FALSE 933.2804056 736.1687247 825.7389842 1112.278564 926.2912825 1002.386964 1298.744798 1243.265187 931.8796287 868.9622925 1.074017151 0.847181438 0.950258707 1.280007859 1.065974083 1.153544835 1.494592814 1.430746993 1.07240514 1 9.763149764 -4.840193482 0.945931014 1.022334423 1.563167339 0.68840525 0.109628285 0.418135598 0.479212902 0.017202616 0.187654985 1.44E-05 4.840193482 0.540832916 MPCESS(ph)PPESADTPTSTR ddPTM_HeLa_Curcumin_4h_R1 1 MPCESSPPESADTPTSTR 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 MPCES(0.041)S(0.957)PPES(0.001)ADTPTSTR 195.6 3.69E-09 12535000 826.24 582.87 799.95 1000.6 1080.9 1337 970.26 699.18 1087.5 849.89 TRUE FALSE FALSE 760.8422322 633.2506856 829.5968507 996.4597823 1068.010973 1059.691129 997.4828843 912.3567634 968.2039708 879.4236142 0.865160112 0.720074689 0.943341567 1.133082813 1.214444275 1.204983709 1.13424619 1.037448561 1.100952891 1 9.780414462 -6.268568305 4.721360291 0.914793802 1.152988572 0.538189328 0.101382797 0.105237469 6.654629832 0.014894755 0.02391177 5.39E-07 6.268568305 0.23819477 MPCESSPPES(ph)ADTPTSTR ddPTM_HeLa_Curcumin_4h_R1 1 MPCESSPPESADTPTSTR 18 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 MPCES(0.291)S(0.291)PPES(0.416)ADT(0.003)PTSTR 113.67 0.0006485 6180900 3882.7 3057.3 3346.4 4017.9 3396.8 4203.9 3571.4 2193.8 4335.5 3709.1 TRUE FALSE FALSE 3575.380198 3321.559389 3470.420528 4001.274994 3356.295379 3331.963752 3671.603872 2862.679521 3859.906497 3837.990949 0.931575985 0.865442215 0.904228429 1.042544146 0.874492781 0.868153103 0.95664735 0.745879696 1.005710161 1 11.90613559 -1 0.133377626 1.014509234 0.434808147 0.377148474 0.065337617 69.8716052 0.624249995 0.200998771 7.682018677 0.1 1 -0.579701087 MPDEPEEPVVAVS(ph)SPAVPPPTK ddPTM_HeLa_Curcumin_4h_R1 1 MPDEPEEPVVAVSSPAVPPPTK 22 0 O60885;O60885-2;O60885-3;M0QZD9 O60885 BRD4 Bromodomain-containing protein 4 1 0 MPDEPEEPVVAVS(0.5)S(0.5)PAVPPPTK 70.02 0.0014846 8055700 3310.6 2336 2638.1 3006 2908.1 2987.5 2458.7 1559.6 2600 2724.9 TRUE FALSE FALSE 3048.562517 2537.913431 2735.870307 2993.561968 2873.422807 2367.858824 2527.684505 2035.11486 2314.786505 2819.590072 1.081207707 0.900100144 0.970307824 1.061701131 1.019092398 0.839788325 0.896472338 0.721776857 0.820965618 1 11.46126972 -3.310645398 0.53900151 1.030297063 0.03559228 0.336155615 0.089275406 3.985387555 0.370919076 0.012225349 3.150504839 0.000489052 3.310645398 -0.994704782 MPEANQLHLPNLNSQVDSPSSEKS(ph)PVMTPFK ddPTM_HeLa_Curcumin_4h_R1 1 MPEANQLHLPNLNSQVDSPSSEKSPVMTPFK 31 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;H0Y8P3;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-9 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 MPEANQLHLPNLNS(0.193)QVDS(0.193)PS(0.193)S(0.193)EKS(0.222)PVMT(0.005)PFK 59.873 0.00053514 22098000 779.12 768.39 810.38 679.12 588 783.35 503.46 770.37 861.87 721.99 TRUE FALSE FALSE 717.4518299 834.8062077 840.4133957 676.3099814 580.988484 620.8743798 517.5857326 1005.252267 767.3250173 747.0790988 0.960342527 1.117426801 1.124932282 0.905272256 0.777680014 0.831069134 0.692812493 1.345576751 1.0271001 1 9.54511719 -6.027859314 24.04030731 1.003497272 0.884265558 0.103376616 0.171409068 763.7213805 659028.8265 0.024156486 0.040132562 9.38E-07 6.027859314 -0.119231714 MPETVPQEEMPGPPLNS(ph)ESGEEAPTGR ddPTM_HeLa_Curcumin_4h_R1 2 MPETVPQEEMPGPPLNSESGEEAPTGR 27 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 0 MPETVPQEEMPGPPLNS(0.554)ES(0.442)GEEAPT(0.004)GR;MPETVPQEEMPGPPLNS(0.825)ES(0.173)GEEAPT(0.002)GR ; 96.77 2.01E-06 10858400 2650.8 1750.59 2167.85 2291.75 2114.4 2833.5 2656.7 2023.9 2504.2 2029.7 TRUE FALSE FALSE 2440.986383 1901.903199 2248.192428 2282.267346 2089.187161 2245.80016 2731.239852 2640.977793 2229.495525 2100.231924 1.16224611 0.905568179 1.070449602 1.086673962 0.99474117 1.069310553 1.300446784 1.257469598 1.061547299 1 11.03633293 -4.766576916 23.9630091 1.059965928 1.278958249 0.662592357 0.066322435 36.56060221 170536.9034 0.010901957 0.034272747 1.71E-05 4.766576916 0.21899232 MPETVPQEEMPGPPLNSES(ph)GEEAPTGR ddPTM_HeLa_Curcumin_4h_R1 2 MPETVPQEEMPGPPLNSESGEEAPTGR 27 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 0 MPETVPQEEMPGPPLNS(0.346)ES(0.654)GEEAPTGR;MPETVPQEEMPGPPLNS(0.066)ES(0.933)GEEAPT(0.001)GR ; 162.29 2.01E-10 17692100 5127.6 3867.2 3746.3 4789.7 4918.7 5436.6 3822.1 3184.8 5583.4 4656.5 TRUE FALSE FALSE 4721.745049 4201.463536 3885.141174 4769.881491 4860.047715 4308.987877 3929.337839 4155.830859 4970.914989 4818.313028 0.979958135 0.87197812 0.806328097 0.989948445 1.00866168 0.894293885 0.81550074 0.862507445 1.031671243 1 12.23431241 -1.000000036 0.113556165 1.053197274 0.419108677 0.357829991 0.064588711 87.19681977 0.689356036 0.372584672 8.727350014 0.099999992 1.000000036 -0.634088596 MPFLSIS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 2 MPFLSISSPK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 MPFLSIS(0.937)S(0.063)PK;MPFLS(0.001)IS(0.5)S(0.5)PK ; 131.09 0.002766 235233000 10483.8 7098.9 10355.2 9744.7 9839.7 12974.2 13099.7 11370.5 9677.5 7618.4 TRUE FALSE FALSE 9653.996168 7712.497284 10738.97282 9704.379013 9722.368004 10283.20467 13467.24233 14837.31311 8615.902462 7883.138833 1.224638608 0.978353603 1.362271178 1.231029824 1.233311782 1.304455609 1.708360415 1.882158036 1.092953282 1 12.94455447 -1 0.391786892 1.087503841 14.17659189 0.852269917 0.106011498 16.87625975 0.201710105 0.028653983 171.3230836 0.1 1 13.08908805 GPVSGTEPEPVYS(ph)MEAADYR ddPTM_HeLa_Curcumin_4h_R1 1 GPVSGTEPEPVYSMEAADYR 20 0 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 1 0 GPVSGTEPEPVYS(1)MEAADYR 161.95 7.51E-06 18023000 1363.8 1051.2 1108 1414 1359.1 1665.5 1671.9 4012 1663.4 1234.9 TRUE FALSE FALSE 1255.853791 1142.061044 1149.063455 1408.149243 1342.89362 1320.056526 1718.809014 5235.240331 1480.929182 1277.812683 0.982815249 0.893762489 0.899242487 1.101999739 1.050931516 1.033059496 1.345118136 4.097032687 1.158956396 1 10.31946065 -4.250890372 3.287922597 0.994639989 4.564776735 0.992395108 0.080411201 0.016965723 0.288206233 0.009737062 0.155069464 5.61E-05 4.250890372 3.570136746 up MPGGPKPGGGPGLST(ph)PGGHPKPPHR ddPTM_HeLa_Curcumin_4h_R1 1 MPGGPKPGGGPGLSTPGGHPKPPHR 25 2 P23246;P23246-2 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 1 0 MPGGPKPGGGPGLS(0.432)T(0.568)PGGHPKPPHR 43.216 0.012819 17020000 3353.2 2375.6 2317.3 2174.5 4652.8 8841.9 7199.9 2267.9 4182.1 2313.5 TRUE FALSE FALSE 3087.790682 2580.936279 2403.181177 2165.502495 4597.318399 7007.990271 7401.909816 2959.37227 3723.334093 2393.893953 1.289861098 1.078133088 1.003879547 0.904594162 1.920435278 2.927443909 3.091995703 1.236216945 1.555346296 1 11.22514353 -5.575306527 4.18680837 1.111823229 2.483718613 0.579345493 0.493629564 0.094576123 3.472398599 0.064970658 0.136721611 2.66E-06 5.575306527 1.371895384 MPLDDLDREDEVR ddPTM_HeLa_Curcumin_4h_R1 2 MPLDDLDREDEVR 13 1 P57740;P57740-3;P57740-2 P57740 NUP107 Nuclear pore complex protein Nup107 0 0 ; ; 112.64 0.0030031 17483900 7154.2 5659.5 6327.2 6152.7 6345.5 7624.4 5952.4 4458.3 6968.7 5845.7 FALSE FALSE TRUE 6587.937521 6148.681962 6561.691598 6127.241758 6269.834057 6043.013495 6119.408324 5817.615147 6204.251045 6048.83764 1.089124541 1.016506365 1.084785539 1.012961849 1.036535353 0.999037146 1.011666817 0.961774062 1.025693102 1 12.56244222 -4.436333317 0.795262398 1.042850926 0.937491465 0.395338861 0.028567698 1.928036114 1.023019533 0.005961776 0.169235934 3.66E-05 4.436333317 -0.105359461 AASSSSPGSPVASS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 1 0 AASSSSPGSPVAS(0.002)S(0.997)PSR;AASSSSPGSPVAS(0.048)S(0.95)PS(0.002)R ; 265.64 4.10E-52 105984000 9485 7576.6 8328.1 9211.1 9866.7 11459.7 6719.6 2132.54 9387.6 9190.9 TRUE FALSE FALSE 8734.252241 8231.487543 8636.746712 9172.986909 9749.046047 9082.829043 6908.133891 2782.741629 8357.803767 9510.283091 0.918400868 0.865535491 0.908148225 0.964533529 1.025105767 0.955053488 0.726385726 0.292603449 0.878817559 1 13.21527257 -4.327108304 2.104036634 0.95494475 0.162942187 0.937787819 0.050645891 0.099227715 0.536568898 0.00759064 0.140479421 4.71E-05 4.327108304 -0.792002563 down MPPSLQERVPR ddPTM_HeLa_Curcumin_4h_R1 1 MPPSLQERVPR 11 1 P14784 P14784 IL2RB Interleukin-2 receptor subunit beta 0 0 41.164 0.018206 800070 1034.7 862.49 779.33 991.93 789.22 120.67 543.29 611.47 871.22 718.51 FALSE FALSE TRUE 952.8024032 937.0397924 808.2126554 987.8256565 779.809067 95.64168177 558.5332552 797.9043881 775.6493457 743.478169 1.28154725 1.260346075 1.087069788 1.328654556 1.048866126 0.128640874 0.751243652 1.073204865 1.043271179 1 9.53814657 -5.499885211 24.80195856 1.156419981 0.649001494 0.48840848 0.236511873 444.7467208 479725.2761 0.033748625 0.07495763 3.16E-06 5.499885211 -0.507418488 MPQDGS(ph)DDEDEEWPTLEK ddPTM_HeLa_Curcumin_4h_R1 4 MPQDGSDDEDEEWPTLEK 18 0 F8WBL2;Q13895 F8WBL2 BYSL Bystin 1 0 MPQDGS(1)DDEDEEWPTLEK;MPQDGS(1)DDEDEEWPTLEK;MPQDGS(1)DDEDEEWPTLEK;MPQDGS(1)DDEDEEWPTLEK ;;; 139.55 0.00015861 111780300 18531.8 15501.8 15458.2 16495 16108.7 18267.7 13834.8 11373.7 19150.3 16306.9 TRUE FALSE FALSE 17064.98848 16841.70652 16031.09449 16426.74806 15916.61427 14478.7731 14222.96725 14841.48877 17049.56 16873.56356 1.011344664 0.998112014 0.950071657 0.97351979 0.943287067 0.85807441 0.842914255 0.879570502 1.010430307 1 14.04247707 -5.574517623 0.967481938 1.003779674 0.846795253 0.898280229 0.019556544 0.125212402 0.214043643 0.003265725 0.012620005 2.66E-06 5.574517623 -0.15698442 MPSFGMLS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 2 MPSFGMLSPGK 11 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 MPSFGMLS(1)PGK;MPS(0.001)FGMLS(0.999)PGK ; 104.24 0.0088364 60198000 3994.5 2565.5 3046.1 3258.8 3784.6 3172.5 2552.8 3316.2 3328.5 2472.5 TRUE FALSE FALSE 3678.33111 2787.250388 3158.991146 3245.315949 3739.471117 2514.487739 2624.424697 4327.294114 2963.371877 2558.419191 1.437735897 1.089442417 1.234743375 1.268484836 1.461633469 0.982828673 1.025799332 1.691393705 1.158282383 1 11.32103695 -9.579325905 1.360819213 0.999879532 1.279066858 0.105536753 0.209680489 0.554909639 1.841302969 0.141495865 0.032975854 2.63E-10 9.579325905 0.279187327 NSPNNMSLSNQPGT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 NSPNNMSLSNQPGTPR 16 0 H0Y9V4;A0A087X159;P81877-4;P81877-5;P81877-3;P81877 H0Y9V4 SSBP2 Single-stranded DNA-binding protein 2 1 0 NSPNNMSLSNQPGT(1)PR 214.81 7.72E-42 0 1059.7 1142.6 985.87 1005.9 1144 1292.3 1177.9 2163 1308.3 914.84 TRUE FALSE FALSE 975.8236268 1241.361253 1022.407209 1001.737852 1130.358547 1024.262413 1210.948704 2822.488743 1164.782763 946.6306219 1.030838855 1.311347028 1.080048739 1.05821408 1.194086184 1.082008535 1.279219873 2.981615719 1.230451177 1 9.886657781 -4.250609464 3.278096216 1.06160111 3.273427182 0.96362201 0.107133853 0.041447088 0.697088906 0.014628226 0.234316478 5.62E-05 4.250609464 2.211826072 up MQAHIQDLEEQLDEEEGAR ddPTM_HeLa_Curcumin_4h_R1 1 MQAHIQDLEEQLDEEEGAR 19 0 P35580;P35580-5;P35580-2;P35580-3;P35580-4 P35580 MYH10 Myosin-10 0 0 77.795 0.0025091 0 1718.9 1137.9 1455.1 1455.2 1327.4 1793.1 1783.8 1159.9 1458.3 1534.5 FALSE FALSE TRUE 1582.847251 1236.255006 1509.027286 1449.178768 1311.571622 1421.190848 1833.848627 1513.54817 1298.328138 1587.823761 0.99686583 0.778584523 0.950374546 0.912682379 0.826018387 0.895055788 1.154944694 0.953221767 0.817677736 1 10.63283508 -7.458790334 24.99998437 0.998618333 0.925970447 0 0.109249312 349.6740485 136403.0707 0.016245106 0.018575722 3.48E-08 7.458790334 -0.072647886 MQAS(ph)IEKGGSLPK ddPTM_HeLa_Curcumin_4h_R1 1 MQASIEKGGSLPK 13 1 P06748;P06748-2 P06748 NPM1 Nucleophosmin 1 0 MQAS(1)IEKGGSLPK 69.379 0.016002 327340000 4033.9 3789.6 3014.7 4531.6 3110.6 9352.7 7023 1750.7 8029.8 5556.9 TRUE FALSE FALSE 3714.612558 4117.156138 3126.427434 4512.84944 3073.508127 7412.844593 7220.046479 2284.480371 7148.95103 5750.001861 0.646019366 0.716026923 0.543726334 0.784843127 0.534522979 1.289189947 1.255659851 0.397300805 1.243295429 1 12.48934671 -4.1639698 20.14060221 0.831142649 0.397097756 0.18800675 0.284369864 64547.09813 13319696.87 0.037252884 1734.470219 6.86E-05 4.1639698 -0.434044893 MQASIEKGGS(ph)LPK ddPTM_HeLa_Curcumin_4h_R1 1 MQASIEKGGSLPK 13 1 P06748;P06748-2 P06748 NPM1 Nucleophosmin 1 0 MQAS(0.171)IEKGGS(0.829)LPK 141.73 0.0087635 89020000 1610.6 985.31 916.48 1451.7 910.46 2677.4 1754.8 495.24 2265.4 1737.9 TRUE FALSE FALSE 1483.119311 1070.475806 950.445555 1445.69325 899.6033591 2122.077059 1804.034965 646.2363962 2016.891288 1798.291896 0.824737805 0.595273664 0.528526852 0.8039258 0.500254359 1.180051506 1.003193625 0.359361235 1.12155946 1 10.8124115 -8.185024499 1.126037316 0.965750037 0.732857833 0.224099348 0.237778607 0.589244137 1.549719716 0.06462903 0.047900168 6.53E-09 8.185024499 -0.232892204 MQDKSSY(ph)LLAADSEVEMEEWIT(ph)ILNK ddPTM_HeLa_Curcumin_4h_R1 1 MQDKSSYLLAADSEVEMEEWITILNK 26 1 A0A0D9SFH5;A0A0A0MT38;Q6ZSL5;A0A088AWN3;A0A0A0MSY4;Q9BZ29-6;Q9BZ29-3;Q9BZ29-5;Q9BZ29;Q9BZ29-4 A0A0D9SFH5 DOCK9 Dedicator of cytokinesis protein 9 2 0 MQDKS(0.206)S(0.216)Y(0.525)LLAADS(0.054)EVEMEEWIT(0.999)ILNK 43.554 0.010994 57628000 2051.3 1689 1947.9 1514.2 1273.9 1584.5 1199.4 1126.6 2074.4 1850.8 TRUE FALSE FALSE 1888.93744 1834.989634 2020.090888 1507.934642 1258.709575 1255.856839 1233.051936 1470.095154 1846.84351 1915.115162 0.986330993 0.958161509 1.054814315 0.787385882 0.65725007 0.655760481 0.643852631 0.767627547 0.96435115 1 10.90321543 -6.075847828 3.603341847 0.994057274 0.678796308 0.927166329 0.041444756 0.03926682 0.981106834 0.005781166 0.010105945 8.40E-07 6.075847828 -0.315260966 MQEAMTQEVS(ph)DVFSDTTTPIK ddPTM_HeLa_Curcumin_4h_R1 1 MQEAMTQEVSDVFSDTTTPIK 21 0 P18206;P18206-2 P18206 VCL Vinculin 1 0 MQEAMT(0.002)QEVS(0.453)DVFS(0.342)DT(0.087)T(0.031)T(0.085)PIK 48.968 0.015763 7326300 1936.1 1381 1418.9 1654.5 1983.9 2168.6 1905.4 1580.5 1330.9 1225.2 TRUE FALSE FALSE 1782.855642 1500.367486 1471.485682 1647.654117 1960.243288 1718.807915 1958.860396 2062.387174 1184.9036 1267.775609 1.406286436 1.183464547 1.160683067 1.299641755 1.546206817 1.35576667 1.545116014 1.62677619 0.934631958 1 10.3080837 -6.357408299 0.047440072 2.62E-17 2.730038633 0.72971771 0.116020942 42.92702697 0.886597478 22.59262469 28.1237158 4.39E-07 6.357408299 2.730038633 MQEAMTQEVSDVFS(ph)DTTTPIK ddPTM_HeLa_Curcumin_4h_R1 1 MQEAMTQEVSDVFSDTTTPIK 21 0 P18206;P18206-2 P18206 VCL Vinculin 1 0 MQEAMTQEVS(0.01)DVFS(0.726)DT(0.118)T(0.073)T(0.073)PIK 91.276 0.00032447 0 2783.1 1786 2880.6 2543.9 3818.7 2954.9 3010.5 2935 1866.5 1971.9 TRUE FALSE FALSE 2562.814698 1940.373882 2987.35757 2533.374016 3773.164497 2342.020431 3094.966528 3829.867989 1661.74962 2040.423378 1.256021042 0.950966306 1.464087111 1.24159233 1.849206658 1.147811016 1.516825655 1.87699672 0.814414125 1 10.99465282 -1.000000002 0.158303351 0.95095503 3.925309462 0.548765447 0.231065441 38.33138661 0.385186546 0.387188397 26.63950548 0.1 1.000000002 2.974354433 MQEEVVR ddPTM_HeLa_Curcumin_4h_R1 1 MQEEVVR 7 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 143.11 0.017116 13176000 4522.1 4019.5 4136.4 4476.2 4097.3 3046 3254.5 2974.9 4419.3 3808 FALSE FALSE TRUE 4164.171013 4366.927669 4289.698623 4457.67867 4048.442374 2414.225265 3345.812511 3881.933315 3934.513847 3940.327717 1.056808294 1.108265095 1.088665444 1.131296428 1.027437986 0.612696567 0.849120366 0.985180319 0.998524521 1 11.94409991 -5.454476136 14.94176762 1.047257334 0.819137487 0.583117223 0.093960404 1.863192019 406.3113829 0.013268478 0.029668852 3.51E-06 5.454476136 -0.228119846 MQHLIAR ddPTM_HeLa_Curcumin_4h_R1 5 MQHLIAR 7 0 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BR70 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ;;;; ;;;; 114.19 0.008201 34185700 23571.2 10732.9 18913.9 14045.7 20506.3 26148.1 21527.6 18249.4 18408 18662.5 FALSE FALSE TRUE 21705.51465 11660.60405 19614.86577 13987.58262 20261.77577 20724.68931 22131.60652 23813.55805 16388.68845 19311.02049 1.123996252 0.603831582 1.015734295 0.724331613 1.049233819 1.073205288 1.146060952 1.233158966 0.848670243 1 14.23713678 -4.766780607 1.766437226 0.996158425 1.22544419 0.232856366 0.16424356 0.576491518 3.150156303 0.024519001 0.159450309 1.71E-05 4.766780607 0.229285765 MQNDTAENETTEKEEK ddPTM_HeLa_Curcumin_4h_R1 4 MQNDTAENETTEKEEK 16 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1;C9J813 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 0 0 ;;; ;;; 149.59 0.00026136 31114500 4541.89 4546.63 4132.34 4714.95 4854.16 5775.69 4093 3791.74 5571.39 4583.81 FALSE FALSE TRUE 4182.394614 4939.620438 4285.488156 4695.440786 4796.277312 4577.746789 4207.838564 4947.824071 4960.222456 4743.097056 0.881785585 1.041433557 0.903521076 0.989952499 1.011212137 0.965138755 0.887150002 1.043163151 1.045777136 1 12.21161367 MQNNSSPSISPNTS(ph)FTSDGSPSPLGGIKR ddPTM_HeLa_Curcumin_4h_R1 1 MQNNSSPSISPNTSFTSDGSPSPLGGIKR 29 1 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 0 MQNNS(0.032)S(0.086)PS(0.112)IS(0.032)PNT(0.274)S(0.375)FT(0.036)S(0.048)DGS(0.004)PSPLGGIKR 76.55 2.59E-05 19007000 1024.7 764.83 856.84 764.39 610.25 1080.8 974.09 260.11 1074.6 1112.2 TRUE FALSE FALSE 943.5939137 830.9384972 888.5952442 761.2271567 602.9731673 856.6298969 1001.420344 339.4163416 956.7190685 1150.848867 0.819911233 0.722022258 0.772121579 0.661448413 0.523937751 0.744346127 0.870157996 0.294926946 0.831315993 1 10.16848267 -7.059501907 0.07605413 1.549321693 1.83E-15 0.384226872 0.146602351 10.56285109 0.62738718 5.877806083 6.538418424 8.72E-08 7.059501907 -1.549321693 MQQNIQELEEQLEEEESAR ddPTM_HeLa_Curcumin_4h_R1 16 MQQNIQELEEQLEEEESAR 19 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;; 265.22 2.94E-55 125311400 17415.36 12470.97 14166.09 14282.24 14516.01 17885.88 13597.62 12237.91 15806.84 14416.89 FALSE FALSE TRUE 16036.91588 13548.90508 14691.09776 14223.14388 14342.91606 14176.14687 13979.13262 15969.19242 14072.8692 14917.87585 1.075013362 0.908232862 0.984798231 0.953429564 0.961458334 0.950279183 0.937072594 1.07047361 0.943356101 1 13.86475451 -7.269949715 24.98504694 1.035422976 0.964779655 0.024898583 0.05214 517.6002139 1519591.719 0.007730854 0.008912801 5.37E-08 7.269949715 -0.070643321 MQQQLDEYQELLDIK ddPTM_HeLa_Curcumin_4h_R1 2 MQQQLDEYQELLDIK 15 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 205.88 2.88E-31 10020000 2745.5 2122.12 2369.5 2452.3 2382.3 2884.1 2405 2042.5 2636.2 2440.3 FALSE FALSE TRUE 2528.190778 2305.546597 2457.315754 2442.153032 2353.892628 2285.905149 2472.477827 2665.248847 2347.015455 2525.100243 1.001223926 0.913051513 0.973155724 0.967150924 0.932197696 0.90527303 0.979160267 1.055502194 0.929474171 1 11.30212495 -7.400779514 20.96825504 1.0005841 0.9588427 0 0.045567293 6.217931633 1043.039231 0.006717341 0.007681481 3.97E-08 7.400779514 -0.0417414 MQRRGALFGMPGGS(ph)GGRK ddPTM_HeLa_Curcumin_4h_R1 3 MQRRGALFGMPGGSGGRK 18 3 Q92995 Q92995 USP13 Ubiquitin carboxyl-terminal hydrolase 13 1 0 MQRRGALFGMPGGS(1)GGRK;MQRRGALFGMPGGS(1)GGRK;MQRRGALFGMPGGS(1)GGRK ;; 44.734 0.018871 206691000 10009.1 7348.1 9427.4 8675.3 8438.7 11355 8033.3 7573.3 9395.5 8878.6 TRUE FALSE FALSE 9216.869173 7983.237022 9776.787737 8639.403907 8338.074014 8999.845003 8258.692777 9882.364307 8364.837156 9187.130689 1.003236972 0.868958687 1.064182939 0.940381083 0.907581953 0.979614344 0.898941471 1.075674728 0.910495065 1 13.16539864 MQYAPNTQVEILPQGHES(ph)PIFK ddPTM_HeLa_Curcumin_4h_R1 2 MQYAPNTQVEILPQGHESPIFK 22 0 P40121-2;P40121;H7C0X8 P40121-2 CAPG Macrophage-capping protein 1 0 MQYAPNTQVEILPQGHES(1)PIFK;MQYAPNTQVEILPQGHES(1)PIFK ; 75.174 0.00071966 31939000 2753.4 2234.73 2118.61 2143.02 2139.38 3649.7 3101.2 2502.96 2578.32 2174.57 TRUE FALSE FALSE 2535.465485 2427.890103 2197.12755 2134.152751 2113.869291 2892.711079 3188.211326 3266.100982 2295.484747 2250.136146 1.126805367 1.078996979 0.97644205 0.948454944 0.939440618 1.28557158 1.416897076 1.451512607 1.020153714 1 11.13579658 -5.046027587 3.585285377 1.041081557 1.426492742 0.890792064 0.060395047 0.068453303 1.787630579 0.010887561 0.032453406 8.99E-06 5.046027587 0.385411185 MRAEDGENYDIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 MRAEDGENYDIKK 13 2 E5RIW3;E5RJD8;O75347;E5RHG6;O75347-2;A0A494C144;E5RIX8 E5RIW3 TBCA Tubulin-specific chaperone A 0 1 ; MRAEDGENYDIK(1)K;MRAEDGENYDIK(1)K 113.52 0.00030438 5258300 2653.71 2177.93 2146.41 1946.02 2621.17 4644.3 3302.19 3902.34 3924.05 2612.33 FALSE TRUE FALSE 2443.666053 2366.180565 2225.957843 1937.967885 2589.91426 3681.019828 3394.840564 5092.145502 3493.591532 2703.108273 0.904020781 0.875355452 0.823480829 0.716940533 0.958124499 1.361772987 1.255902547 1.883811149 1.292434923 1 11.40040358 -4.136428711 0.934879298 0.921327144 2.520630836 0.733588893 0.170087357 0.722839189 0.40796667 0.020454705 1.234262672 7.30E-05 4.136428711 1.599303692 MRAIEIYT(ph)DMGR ddPTM_HeLa_Curcumin_4h_R1 1 MRAIEIYTDMGR 12 1 M0R027 M0R027 NAPA 1 0 MRAIEIY(0.025)T(0.975)DMGR 61.48 0.014228 13433000 783.99 744.97 689.4 917.41 919.71 774.13 767.54 772.98 811.29 708.62 TRUE FALSE FALSE 721.9363642 809.3618873 714.9497705 913.6140005 908.7430589 613.5667118 789.0751067 1008.658044 722.2935167 733.2444923 0.984577957 1.103809024 0.975049629 1.245988221 1.239345223 0.836783253 1.07614188 1.375609438 0.985065042 1 9.518150519 -6.286423004 24.3251081 1.001426999 1.137437482 0.215544057 0.135932317 685.2050612 667143.1423 0.020651678 0.031555489 5.17E-07 6.286423004 0.136010484 MRALCADEYRARCR ddPTM_HeLa_Curcumin_4h_R1 1 MRALCADEYRARCR 14 3 O14654 O14654 IRS4 Insulin receptor substrate 4 0 0 93.667 0.0019739 27629000 2270.9 1693.9 2108.3 2189.2 2050.8 2681.2 2282 2238.5 2428 2482.9 FALSE FALSE TRUE 2091.155869 1840.313168 2186.435453 2180.14167 2026.345549 2125.088897 2346.026778 2921.008345 2161.654475 2569.18059 0.81393884 0.716303546 0.851024432 0.848574709 0.788712774 0.827146564 0.91314203 1.136941621 0.841378953 1 11.32709259 -4.276099516 3.65221317 0.873989353 1.162140872 0.556808087 0.074943406 0.209734636 5.13319414 0.013907872 0.160237154 5.30E-05 4.276099516 0.288151519 MREDYDS(ph)VEQDGDEPGPQR ddPTM_HeLa_Curcumin_4h_R1 3 MREDYDSVEQDGDEPGPQR 19 1 Q9Y5S9;Q9Y5S9-2 Q9Y5S9 RBM8A RNA-binding protein 8A 1 0 MREDY(0.013)DS(0.987)VEQDGDEPGPQR;MREDYDS(1)VEQDGDEPGPQR;MREDY(0.001)DS(0.999)VEQDGDEPGPQR ;; 124.45 7.53E-05 123007000 3001.75 2118.68 2690 2541.35 2654.26 3302.65 2630.9 1983.69 3091.65 2743.56 TRUE FALSE FALSE 2764.15832 2301.809259 2789.693766 2530.834567 2622.609683 2617.643161 2704.715973 2588.507949 2752.50373 2838.898506 0.973672822 0.810810691 0.982667665 0.891484694 0.923812414 0.922062961 0.952734297 0.911800103 0.969567501 1 11.47111556 -7.495261951 21.52232637 0.988385337 0.915834426 0.346557722 0.042495773 43.09497124 33586.10513 0.006776896 0.007359217 3.20E-08 7.495261951 -0.072550911 MREDYDSVEQDGDEPGPQR ddPTM_HeLa_Curcumin_4h_R1 3 MREDYDSVEQDGDEPGPQR 19 1 Q9Y5S9;Q9Y5S9-2 Q9Y5S9 RBM8A RNA-binding protein 8A 0 0 ;; ;; 190.18 6.21E-10 39282000 3867.8 3811.1 3824 3809.9 4485.1 4607.8 3902.9 4341.2 4521.4 4105.7 FALSE FALSE TRUE 3561.659549 4140.514502 3965.720804 3794.135643 4431.618112 3652.090339 4012.40487 5664.811896 4025.413732 4248.372769 0.83835853 0.974611864 0.933468182 0.893079739 1.043133066 0.859644513 0.944456875 1.333407449 0.947518956 1 12.05269464 -4.262762277 5.723056119 0.928530582 1.346052209 0.80150364 0.059071473 0.050885646 7.073296927 0.009558338 0.082663463 5.46E-05 4.262762277 0.417521627 MREY(ph)ERMK ddPTM_HeLa_Curcumin_4h_R1 1 MREYERMK 8 2 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;H0YBA1 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 0 MREY(1)ERMK 53.775 0.020329 8523200 3238.4 2650 2901.9 2668.2 3084.6 3249.4 2927 2833.1 3396.1 2826.1 TRUE FALSE FALSE 2982.077223 2879.054192 3009.446967 2657.159695 3047.81816 2575.437812 3009.123742 3696.899148 3023.556327 2924.306765 1.019755266 0.984525367 1.029114662 0.908646017 1.042236128 0.880700289 1.029004131 1.264196764 1.033939518 1 11.51387895 -4.276036174 4.438804389 0.996240687 1.279583742 0.717676824 0.051499349 0.068339655 3.266904873 0.006396344 0.058884067 5.30E-05 4.276036174 0.283343055 LHPDGS(ph)PDVAGEK ddPTM_HeLa_Curcumin_4h_R1 3 LHPDGSPDVAGEK 13 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 0 LHPDGS(1)PDVAGEK;LHPDGS(1)PDVAGEK;LHPDGS(1)PDVAGEK ;; 131.86 0.0015278 74656000 20585 16842.8 18835.5 19821.9 19698.1 20170.9 12796.6 3586.68 20899.6 18594 TRUE FALSE FALSE 18955.67553 18298.61658 19533.5602 19739.88223 19463.21302 15987.22797 13155.63816 4680.242221 18606.96617 19240.14012 0.985215046 0.951064622 1.015250413 1.025973933 1.011594141 0.830930953 0.683759997 0.243254061 0.967090991 1 14.23183169 -4.326873509 1.307619348 0.994867052 5.16E-20 0.978738224 0.03390452 0.109656041 0.173950233 0.004767768 0.14016281 4.71E-05 4.326873509 -0.994867052 down MRRS(ph)MK ddPTM_HeLa_Curcumin_4h_R1 1 MRRSMK 6 2 Q8N9Z2;Q8N9Z2-2 Q8N9Z2 CCDC71L Coiled-coil domain-containing protein 71L 1 0 MRRS(1)MK 50.632 0.0079496 0 1332.3 1106.5 1132.2 1040.3 1236.9 1809.3 1349.8 983.29 1253.6 1188.7 TRUE FALSE FALSE 1226.847049 1202.14093 1174.160328 1035.995514 1222.150775 1434.030785 1387.671755 1283.090594 1116.083216 1230.007237 0.997430757 0.977344599 0.954596276 0.84226782 0.993612671 1.165871828 1.128181781 1.043156948 0.90737939 1 10.26445109 -5.328522112 7.475936045 0.981174635 1.113744616 0.583516343 0.058395593 0.161510429 16.05020567 0.008173753 0.018386946 4.69E-06 5.328522112 0.132569981 QGSGRES(ph)PSLASR ddPTM_HeLa_Curcumin_4h_R1 2 QGSGRESPSLASR 13 1 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3;H3BUF6;H3BSK9;Q8WWM7-7 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 0 QGS(0.039)GRES(0.948)PS(0.013)LASR;QGS(0.004)GRES(0.955)PS(0.039)LAS(0.001)R ; 63.062 0.020382 619686000 6254 5482.7 5292.6 5127.6 5365.4 6221.6 3775.9 966.96 5985.3 5303.1 TRUE FALSE FALSE 5758.989301 5956.600158 5488.748412 5106.38335 5301.421109 4931.170028 3881.841592 1261.781653 5328.727564 5487.38233 1.049496637 1.085508499 1.00024895 0.930568173 0.966111124 0.898637954 0.70741227 0.229942362 0.97108735 1 12.42190238 -4.324955074 1.335665953 1.017797876 1.62E-24 0.96491568 0.044744624 0.149681083 0.249675662 0.006830624 0.199081435 4.73E-05 4.324955074 -1.017797876 down MS(ph)DDEDDDEEEYGKEEHEK ddPTM_HeLa_Curcumin_4h_R1 3 MSDDEDDDEEEYGKEEHEK 19 1 Q7KZ85;Q7KZ85-3 Q7KZ85 SUPT6H Transcription elongation factor SPT6 1 0 MS(1)DDEDDDEEEYGKEEHEK;MS(1)DDEDDDEEEYGKEEHEK;MS(1)DDEDDDEEEYGKEEHEK ;; 136.68 7.42E-05 42672000 5275.7 5293.8 6242.3 5299.8 7443.8 5681.3 5978 4614.01 4656.5 4672.8 TRUE FALSE FALSE 4858.122778 5751.372483 6473.645129 5277.870832 7355.037547 4502.934339 6145.726591 6020.800409 4145.6936 4835.179452 1.004745083 1.189484804 1.338863468 1.091556349 1.521150894 0.931285877 1.271044157 1.245207229 0.857402221 1 12.23935372 -7.216945408 4.220541015 1.001644243 1.230041076 0.39799185 0.151033854 0.165369571 6.472864269 0.021994184 0.026652109 6.07E-08 7.216945408 0.228396833 MS(ph)EIPSTIVSK ddPTM_HeLa_Curcumin_4h_R1 1 MSEIPSTIVSK 11 0 E9PQV5;Q494V2;Q494V2-2 E9PQV5 CCDC37 Coiled-coil domain-containing protein 37 1 0 MS(0.577)EIPS(0.389)T(0.034)IVSK 90.657 0.019581 22511000 491.1 831.83 671.87 762.75 703.27 1097.1 882.49 622.59 672.12 659.47 TRUE FALSE FALSE 452.2289168 903.7296786 696.7700932 759.5939426 694.8839646 869.5490931 907.2502943 812.4148249 598.3901176 682.3865334 0.662716649 1.324366227 1.021078317 1.113143219 1.018314299 1.274276456 1.329525496 1.190549322 0.876907864 1 9.414445366 -7.258380698 24.99760636 0.840727306 1.175772992 0.58552309 0.129093728 168.8355029 1379839.441 0.027150095 0.032493974 5.52E-08 7.258380698 0.335045686 MS(ph)GFIYQGK ddPTM_HeLa_Curcumin_4h_R1 2 MSGFIYQGK 9 0 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5;E7EUY6;Q15052-2;Q15052;F6SJA5;Q14155-6;Q14155-2;Q14155-3;Q14155;E9PDQ5 B1ALK7;Q14155-6 ARHGEF7;ARHGEF6 Rho guanine nucleotide exchange factor 7;Rho guanine nucleotide exchange factor 6 1 0 MS(1)GFIYQGK;MS(1)GFIYQGK ; 166.29 0.0006146 505080000 5856.9 5386.6 5992.7 5758.1 5386.3 7414.5 6229.1 5091.5 5483.4 5588 TRUE FALSE FALSE 5393.320185 5852.193702 6214.794734 5734.274508 5322.07189 5876.649121 6403.871781 6643.874912 4881.884739 5782.182584 0.932748163 1.012108078 1.074818141 0.991714534 0.920426122 1.016337522 1.107518085 1.149025444 0.844297922 1 12.49739845 -4.764094789 2.851376533 0.977875918 1.140743798 0.534527424 0.058969358 0.12721588 2.044078855 0.006663284 0.029356956 1.72E-05 4.764094789 0.162867881 MS(ph)GGSTMSSGGGNTNNSNSK ddPTM_HeLa_Curcumin_4h_R1 2 MSGGSTMSSGGGNTNNSNSK 20 0 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 0 MS(0.507)GGS(0.188)T(0.261)MS(0.044)SGGGNTNNSNSK;MS(0.999)GGS(0.001)TMSSGGGNTNNSNSK ; 174.02 1.22E-06 2754780 1860.93 1544.48 1533.7 1791.8 1410.14 1848.63 1665.97 1151.02 2030.24 1605.3 TRUE FALSE FALSE 1713.635427 1677.977969 1590.540271 1784.386006 1393.325001 1465.2033 1712.712634 1501.960699 1807.527751 1661.084056 1.031636792 1.010170415 0.957531478 1.074229808 0.838804633 0.882076554 1.031081256 0.904205115 1.08816152 1 10.69790936 -5.769320317 24.99999966 1.013811648 0.920118602 0.467584296 0.0578728 124.8041092 395905.9265 0.00760178 0.013960888 1.70E-06 5.769320317 -0.093693046 MS(ph)LPLLAGGVADDINTNKK ddPTM_HeLa_Curcumin_4h_R1 1 MSLPLLAGGVADDINTNKK 19 1 Q15398-1;Q15398-3;Q15398 Q15398-1 DLGAP5 Disks large-associated protein 5 1 0 MS(1)LPLLAGGVADDINTNKK 110.33 0.00022596 19222000 1405.3 1316.3 1559 1258.6 1795.5 2602.1 2532.1 773.69 1419.5 1296.7 TRUE FALSE FALSE 1294.069022 1430.075107 1616.777911 1253.392247 1774.089835 2062.395128 2603.143911 1009.584519 1263.784401 1341.760228 0.964456238 1.065820164 1.20496783 0.934140259 1.322210778 1.537081726 1.940096193 0.752432885 0.941885424 1 10.38991117 -5.623378517 4.074645336 1.005325541 1.459426433 0.28903143 0.281691162 0.170122855 5.223607773 0.037275988 0.077332873 2.38E-06 5.623378517 0.454100892 MS(ph)PMGTASGSNSPTSDSASVQR ddPTM_HeLa_Curcumin_4h_R1 12 MSPMGTASGSNSPTSDSASVQR 22 0 O76080;Q5QPB1 O76080 ZFAND5 AN1-type zinc finger protein 5 1 0 MS(0.963)PMGT(0.034)AS(0.003)GSNSPTSDSASVQR;MS(0.481)PMGT(0.481)AS(0.012)GS(0.004)NS(0.014)PT(0.005)S(0.002)DSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(0.5)PMGT(0.5)ASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(0.856)PMGT(0.06)AS(0.016)GS(0.006)NS(0.006)PT(0.009)S(0.046)DS(0.001)ASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(0.999)PMGT(0.001)ASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR;MS(1)PMGTASGSNSPTSDSASVQR ;;;;;;;;;;; 298.76 9.11E-103 185973100 22168.5 18855.46 18640.72 18969.26 18860.26 25738.76 21147.04 13247.97 23942.52 20237.29 TRUE FALSE FALSE 20413.83983 20485.24194 19331.56148 18890.77023 18635.36372 20400.25104 21740.36903 17287.21507 21316.08546 20940.53432 0.974848087 0.978257843 0.923164671 0.902115005 0.889918253 0.974199165 1.038195525 0.825538394 1.017934172 1 14.35401063 -6.834330486 4.70575298 0.987527033 0.930161184 0.273853433 0.053182302 0.242875028 10.13731771 0.008237233 0.011007507 1.46E-07 6.834330486 -0.05736585 MS(ph)SHTETSSFLQTLTGR ddPTM_HeLa_Curcumin_4h_R1 1 MSSHTETSSFLQTLTGR 17 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 MS(0.947)S(0.051)HT(0.002)ETSSFLQTLTGR 76.341 0.012529 8037400 735.51 777.17 548.8 608 960.95 1111.1 756.87 440.27 908.26 804.75 TRUE FALSE FALSE 677.2936074 844.3451118 569.1390108 605.4842571 949.4912989 880.6453353 778.1057352 574.5062962 808.6261504 832.7150026 0.813355836 1.013966494 0.683473948 0.72712063 1.14023561 1.057559108 0.934420219 0.689919474 0.971071913 1 9.701679006 -4.258392185 23.8917897 0.915551484 0.689919315 0.205610719 0.138099551 214.2838514 1679942.42 0.019948774 0.187101532 5.52E-05 4.258392185 -0.225632169 MS(ph)SRLGAVPAT(ph)S(ph)GPTTFK ddPTM_HeLa_Curcumin_4h_R1 1 MSSRLGAVPATSGPTTFK 18 1 G3XAG1;Q96ME7-3;Q96ME7 G3XAG1 ZNF512 Zinc finger protein 512 3 0 MS(0.847)S(0.269)RLGAVPAT(0.934)S(0.934)GPT(0.012)T(0.004)FK 61.167 0.0062672 0 1364.4 1245.6 1409.8 1739.1 1439.7 1297.9 1070.7 1771.3 1582 1436.8 TRUE FALSE FALSE 1256.4063 1353.264114 1462.048428 1731.904065 1422.532518 1028.70091 1100.74096 2311.361216 1408.458558 1486.728693 0.845081087 0.910229365 0.983399618 1.164909289 0.956820518 0.691922416 0.740377828 1.554662412 0.947354124 1 10.53792568 -6.713464005 7.074262861 0.923570834 0.99261189 0.030592973 0.226651037 0.889164109 103.7398437 0.035186452 0.049609485 1.93E-07 6.713464005 0.069041057 GVSMSLPSS(ph)PLLPR ddPTM_HeLa_Curcumin_4h_R1 2 GVSMSLPSSPLLPR 14 0 Q9C0D5-2;Q9C0D5 Q9C0D5-2 TANC1 Protein TANC1 1 0 GVSMS(0.029)LPS(0.223)S(0.747)PLLPR;GVSMS(0.001)LPS(0.209)S(0.791)PLLPR ; 141.73 0.00072386 148421000 6673 4624 5011 4933.3 4698.1 5906.9 3702.5 828.33 6738.1 4565.7 TRUE FALSE FALSE 6144.825009 5023.677956 5196.712068 4912.887312 4642.078226 4681.742356 3806.382185 1080.884004 5998.947288 4724.357735 1.300668864 1.063356807 1.099982762 1.039905864 0.98258398 0.990979646 0.805693048 0.228789618 1.269791075 1 12.2059025 -4.324196697 1.308231796 1.120378327 3.52E-27 0.87247982 0.101439831 0.379778881 0.600895226 0.018464508 0.547646138 4.74E-05 4.324196697 -1.120378327 down MSCFSRPSMS(ph)PTPLDR ddPTM_HeLa_Curcumin_4h_R1 1 MSCFSRPSMSPTPLDR 16 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 MSCFSRPS(0.021)MS(0.976)PT(0.003)PLDR 125.36 0.001183 29333000 3304.6 2496.3 2640.2 2470.5 2536 4019.2 3193.5 3419.6 3420.8 2917.6 TRUE FALSE FALSE 3043.037423 2712.069049 2738.048135 2460.277726 2505.759856 3185.572614 3283.101015 4462.220298 3045.546798 3018.986383 1.007966594 0.898337622 0.906942857 0.814935019 0.830000384 1.055179524 1.087484539 1.478052476 1.008797792 1 11.55984853 -4.159513956 1.711532429 0.965170052 1.750548437 0.81431467 0.077173967 0.468477341 1.085340925 0.012848966 0.648786917 6.93E-05 4.159513956 0.785378385 MSCFSRPSMSPT(ph)PLDR ddPTM_HeLa_Curcumin_4h_R1 1 MSCFSRPSMSPTPLDR 16 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 MSCFSRPS(0.001)MS(0.189)PT(0.81)PLDR 100.69 0.00412 25931000 4179.1 2666.1 3620.7 3769.7 3681.2 5114.7 4139.7 4652.3 3776.5 3596.4 TRUE FALSE FALSE 3848.319825 2896.545804 3754.886327 3754.10198 3637.304094 4053.853565 4255.848841 6070.764853 3362.227398 3721.374632 1.034112446 0.778353724 1.009005192 1.008794424 0.977408741 1.089343043 1.14362279 1.631323221 0.903490707 1 11.86161992 -3.72052895 1.207523309 0.99507801 3.027051985 0.863419388 0.078774168 1.188569803 0.579669599 0.010979883 4.164888227 0.000190314 3.72052895 2.031973975 MSDRPT(ph)ARR ddPTM_HeLa_Curcumin_4h_R1 1 MSDRPTARR 9 2 H0Y3H5;J3KRM4;A0A5F9ZHR4;P55087 H0Y3H5 AQP4 Aquaporin-4 1 0 MSDRPT(1)ARR 94.262 0.019381 16393000 2678.6 2109 2644.7 2116.1 2710.1 1448.9 1725.2 2049.8 2213.3 2427.5 TRUE FALSE FALSE 2466.585984 2291.292562 2742.714909 2107.344139 2677.783828 1148.381808 1773.604469 2674.774584 1970.506527 2511.855444 0.981977681 0.912191252 1.091907942 0.838959162 1.066058094 0.457184672 0.706093367 1.064860078 0.784482456 1 11.29453773 -5.301295731 24.99986245 0.985500123 0.739050327 0.240879168 0.164917535 380.9795531 238968.5483 0.020072939 0.044885032 5.00E-06 5.301295731 -0.246449797 MSDT(ph)GSPGMQR ddPTM_HeLa_Curcumin_4h_R1 2 MSDTGSPGMQR 11 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4;A0A0U1RQL3 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 0 MSDT(0.63)GS(0.369)PGMQR;MS(0.003)DT(0.498)GS(0.498)PGMQR ; 145.09 0.0029044 31908000 3660.1 3191.9 3482.3 3348.6 3242.7 4093.9 3060.8 2232.6 4101.9 3298.3 TRUE FALSE FALSE 3370.399223 3467.793613 3611.357101 3334.74438 3204.03292 3244.778992 3146.67781 2913.309462 3651.931832 3412.915679 0.987542483 1.016079487 1.05814425 0.97709545 0.93879639 0.950735177 0.921991079 0.853613079 1.070032833 1 11.73678906 -4.314504386 0.712205505 0.999592483 0.779659761 0.705860535 0.033346535 0.985912715 0.363841357 0.00451127 0.171190054 4.85E-05 4.314504386 -0.219932722 MSDTGS(ph)PGMQR ddPTM_HeLa_Curcumin_4h_R1 2 MSDTGSPGMQR 11 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4;A0A0U1RQL3 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 0 MS(0.008)DT(0.223)GS(0.769)PGMQR;MS(0.001)DT(0.024)GS(0.975)PGMQR ; 152.96 0.00048023 86023000 6721.2 5805.3 5675.8 5562 6165.8 6385.4 5292.3 4721.2 6721.2 5973.2 TRUE FALSE FALSE 6189.209928 6307.084264 5886.150141 5538.985918 6092.276862 5060.996062 5440.787695 6160.672146 5983.901176 6180.768255 1.001365797 1.020436943 0.952333092 0.896164633 0.985682784 0.81882961 0.880276928 0.996748607 0.968148445 1 12.59357046 -6.545176833 3.891113642 1.002025346 0.912515294 0.379108205 0.049093933 0.149659799 5.024490216 0.007223472 0.010645288 2.85E-07 6.545176833 -0.089510052 MSDYS(ph)PNSTGSVQNTSR ddPTM_HeLa_Curcumin_4h_R1 1 MSDYSPNSTGSVQNTSR 17 0 H7C1W4;Q93075 H7C1W4 TATDN2 Putative deoxyribonuclease TATDN2 1 0 MSDYS(0.915)PNS(0.053)T(0.024)GS(0.008)VQNTSR 115.2 0.00084513 8662300 2046.4 1452.2 1901.7 1759.9 1471.7 1855.4 1232 794.62 1740.7 1811.2 TRUE FALSE FALSE 1884.425281 1577.721697 1972.178675 1752.618 1454.150939 1470.569125 1266.566604 1036.89598 1549.749565 1874.139065 1.005488502 0.841838115 1.052311812 0.935158993 0.775903435 0.784663824 0.675812499 0.55326523 0.826912791 1 10.87201229 -4.476267169 0.509536864 1.003986861 0.309698954 0.704898708 0.081189824 0.813657609 0.162468799 0.011922067 0.322004306 3.34E-05 4.476267169 -0.694287907 MSEET(ph)AT(ph)SDNDNSYARVR ddPTM_HeLa_Curcumin_4h_R1 1 MSEETATSDNDNSYARVR 18 1 Q7Z699 Q7Z699 SPRED1 "Sprouty-related, EVH1 domain-containing protein 1" 2 0 MS(0.37)EET(0.677)AT(0.667)S(0.286)DNDNSYARVR 54.008 0.0084471 0 5258.8 3985.9 4820.4 4830.2 4528 5129.5 5144.7 5733.7 4919 4535.4 TRUE FALSE FALSE 4842.560431 4330.423435 4999.048264 4810.213912 4474.006557 4065.583879 5289.046436 7481.878735 4379.398007 4693.004812 1.031867774 0.922740037 1.065212687 1.024975278 0.953335174 0.866307204 1.127006395 1.594261893 0.933175691 1 12.19629622 -4.297293405 3.305932115 1.000475605 1.652490114 0.899219387 0.061780932 0.05880626 1.056860111 0.007969008 0.092211784 5.04E-05 4.297293405 0.652014509 MSEMIFR ddPTM_HeLa_Curcumin_4h_R1 1 MSEMIFR 7 0 Q6ZWL3-2;Q6ZWL3 Q6ZWL3-2 CYP4V2 Cytochrome P450 4V2 0 0 48.504 0.020098 392310 0 0 0 0 0 189.06 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 149.8468249 0 0 0 0 0 MSES(ph)PTPCSGSSFEETEALVNTAAK ddPTM_HeLa_Curcumin_4h_R1 1 MSESPTPCSGSSFEETEALVNTAAK 25 0 H0Y911;Q4VXL4;D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-2;O95359-6;O95359-1;O95359-5;O95359-3;O95359 H0Y911 TACC2 Transforming acidic coiled-coil-containing protein 2 1 0 MS(0.198)ES(0.7)PT(0.101)PCSGSSFEETEALVNTAAK 105.44 2.12E-07 7616900 3767.4 3207.5 3294.4 3096.8 3248.3 3032.9 1787 2104 4225.8 3207.7 TRUE FALSE FALSE 3469.206315 3484.742008 3416.493362 3083.986262 3209.566144 2403.842352 1837.138411 2745.499914 3762.240312 3319.167336 1.045203801 1.0498844 1.029322422 0.929144556 0.966979311 0.72423054 0.55349376 0.827165261 1.133489195 1 11.69660565 -5.293824152 2.701083665 1.01801667 0.676315303 0.780273108 0.078393416 0.077355739 1.109699699 0.009415798 0.025477014 5.08E-06 5.293824152 -0.341701366 MSGGST(ph)MSSGGGNTNNSNSK ddPTM_HeLa_Curcumin_4h_R1 1 MSGGSTMSSGGGNTNNSNSK 20 0 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 0 MS(0.002)GGS(0.015)T(0.563)MS(0.413)S(0.007)GGGNTNNSNSK 160.84 7.74E-05 1237100 706.42 651.47 767.8 724.9 883.53 736.1 507.6 388.87 744.69 538.59 TRUE FALSE FALSE 650.5061116 707.7801639 796.2553434 721.9005559 872.9944818 583.4245624 521.8418899 507.4346729 662.9993701 557.3059624 1.167233361 1.270002856 1.428757984 1.295339732 1.566454588 1.046865818 0.936365166 0.910513626 1.189650596 1 9.122325778 -3.005279449 12.44295074 1.13932754 1.152638978 0 0.207953204 0 0 0.030028318 0 0.000987917 3.005279449 0.013311438 MSGGSTMS(ph)SGGGNTNNSNSK ddPTM_HeLa_Curcumin_4h_R1 4 MSGGSTMSSGGGNTNNSNSK 20 0 A0A6E1WJ75;Q86U70-3;Q86U70-2;Q86U70 A0A6E1WJ75 LDB1 LIM domain-binding protein 1 1 0 MS(0.142)GGS(0.216)T(0.216)MS(0.419)S(0.008)GGGNTNNSNSK;MS(0.26)GGS(0.044)T(0.194)MS(0.476)S(0.026)GGGNTNNSNSK;MS(0.144)GGS(0.025)T(0.205)MS(0.622)S(0.003)GGGNTNNSNSK;MS(0.049)GGS(0.198)T(0.198)MS(0.503)S(0.052)GGGNTNNSNSK ;;; 119.88 5.04E-05 8862530 1847.44 1444.31 1431.64 1426.95 1589.33 1596.27 1665.79 962.043 1782.34 1743.6 TRUE FALSE FALSE 1701.213175 1569.149721 1484.697838 1421.045659 1570.378278 1265.185608 1712.527584 1255.365482 1586.821761 1804.18997 0.942923529 0.869725332 0.822916579 0.787636381 0.870406279 0.701248554 0.949194715 0.695805598 0.879520332 1 10.81713554 -7.217925235 0.995146069 0.984028533 0.802643465 0.358907965 0.077272854 0.236358845 0.460756956 0.013515103 0.01643479 6.05E-08 7.217925235 -0.181385068 SAES(ph)PT(ph)SPVTSETGSTFK ddPTM_HeLa_Curcumin_4h_R1 1 SAESPTSPVTSETGSTFK 18 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 2 0 S(0.003)AES(0.996)PT(0.639)S(0.337)PVT(0.021)S(0.005)ETGSTFK 119.96 0.0016543 13372000 1424.9 1456.6 1486.1 1293.2 1826.5 2126.6 2806.1 11006 1558.9 1428 TRUE FALSE FALSE 1312.117661 1582.502014 1541.176173 1287.849081 1804.72018 1685.519188 2884.831614 14361.67873 1387.89257 1477.622894 0.887992239 1.070978272 1.043010487 0.87156817 1.22136723 1.140696449 1.952346317 9.719447902 0.939273868 1 10.52906241 -4.250500823 3.310492551 0.992938541 11.02247956 0.998107888 0.112885235 0.012815288 0.222273224 0.020862448 0.330680725 5.62E-05 4.250500823 10.02954102 up MSPAS(ph)PIDDIER ddPTM_HeLa_Curcumin_4h_R1 2 MSPASPIDDIER 12 0 B4DWJ3;Q96CJ1-2;Q96CJ1 B4DWJ3 EAF2 ELL-associated factor 2 1 0 MS(0.059)PAS(0.941)PIDDIER;MS(0.005)PAS(0.995)PIDDIER ; 116.19 0.0039552 7213900 2676.7 2659.3 2884 2497.7 2944 2909.8 2258.21 1726.39 2500.2 2238.9 TRUE FALSE FALSE 2464.836371 2889.158042 2990.883577 2487.365179 2908.894723 2306.27468 2321.569295 2252.758364 2225.934315 2316.701608 1.063942098 1.24709977 1.29100941 1.073666617 1.255619072 0.995499235 1.002101128 0.972399016 0.960820464 1 11.17785652 -2.677343389 14.14003554 1.070753054 0.463452205 0 0.122874838 0 0 0.01683245 0 0.002102116 2.677343389 -0.607300849 MSPNETLFLES(ph)TNK ddPTM_HeLa_Curcumin_4h_R1 3 MSPNETLFLESTNK 14 0 Q9HB90;Q9NQL2 Q9HB90 RRAGC;RRAGD Ras-related GTP-binding protein C;Ras-related GTP-binding protein D 1 0 MSPNET(0.001)LFLES(0.769)T(0.23)NK;MSPNET(0.002)LFLES(0.97)T(0.027)NK;MSPNETLFLES(0.76)T(0.239)NK ;; 187.75 2.17E-05 155621000 13853.5 12371.9 14438.9 13472.4 16008.1 22371.4 14353 9466 13756.8 13193 TRUE FALSE FALSE 12756.98086 13441.27191 14974.01834 13416.65478 15817.21386 17731.31946 14755.70655 12352.13982 12247.71346 13651.45577 0.93447769 0.984603557 1.096880698 0.982800297 1.158646677 1.29885924 1.080888866 0.904822169 0.897172702 1 13.73676719 -6.508844399 1.398789177 0.968782305 1.108929776 0.275177404 0.101940236 0.411327075 1.60676567 0.017566338 0.029383569 3.10E-07 6.508844399 0.140147471 MSPRVVSNSSVLASQSVGITNVRTVFSNVFNNTTAFPILR ddPTM_HeLa_Curcumin_4h_R1 1 MSPRVVSNSSVLASQSVGITNVRTVFSNVFNNTTAFPILR 40 2 Q9UF12 Q9UF12 PRODH2 Probable proline dehydrogenase 2 0 0 23.34 0.019444 14422000 1189.6 802.44 918.95 1081.2 1042.4 1735.2 1444.7 728.33 1327.7 828.07 FALSE FALSE TRUE 1095.441905 871.799338 953.0070954 1076.726281 1029.970061 1375.29996 1485.234394 950.3944642 1182.054632 856.8453709 1.278459267 1.017452352 1.112227629 1.256616792 1.20204893 1.605073689 1.733375057 1.109178501 1.379542531 1 9.742891064 -5.388514232 4.239240377 1.134258906 1.505971806 0.343708505 0.186730182 0.153225883 4.549167861 0.025371758 0.058845223 4.09E-06 5.388514232 0.3717129 MSQPGSPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 MSQPGSPSPK 10 0 F5GWX5;A0A2R8YER1;Q14839-2;Q14839;A0A2R8YFD8;A0A0C4DGG9;A0A2U3TZM0;A0A2R8Y521;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8Y212;A0A2R8Y8C1;A0A2R8YDJ9;A0A2R8YD40;A0A2R8YE38;A0A2R8Y4X2;A0A2R8YDW2;A0A2R8Y5M9;A0A2R8Y7I0;A0A2R8Y7M9 F5GWX5 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 0 MSQPGS(0.299)PS(0.701)PK;MS(0.001)QPGS(0.318)PS(0.681)PK;MSQPGS(0.287)PS(0.713)PK ;; 112.64 0.0075424 391752000 47225 34876.1 41936 42607 41521 46811 40240 17544.6 44817 38491.4 TRUE FALSE FALSE 43487.09142 37890.63468 43490.18505 42430.70352 41025.88919 37101.87093 41369.0261 22893.86777 39900.68723 39828.97328 1.091845655 0.951333453 1.091923328 1.065322554 1.030051387 0.931529685 1.038666646 0.574804367 1.001800547 1 15.28153067 -4.261098343 24.96375062 1.034164393 0.574804227 0.867852512 0.052230943 6.982000876 510863.5105 0.007561883 0.059149829 5.48E-05 4.261098343 -0.459360167 SNSGLGGEVSGVMS(ph)KPNVDPQPWFQDGPK ddPTM_HeLa_Curcumin_4h_R1 1 SNSGLGGEVSGVMSKPNVDPQPWFQDGPK 29 1 C9JRJ5;Q9UGP4 C9JRJ5 LIMD1 LIM domain-containing protein 1 1 0 S(0.076)NS(0.182)GLGGEVS(0.055)GVMS(0.688)KPNVDPQPWFQDGPK 59.561 0.0010517 22642000 1017.5 787.98 1097.3 940.74 848.94 1425.1 1162.7 2551.4 978.82 1032 TRUE FALSE FALSE 936.9638013 856.08948 1137.966903 936.8474671 838.816945 1129.518196 1195.322233 3329.310115 871.4458949 1067.861923 0.877420368 0.801685556 1.065649855 0.877311427 0.78551068 1.057738057 1.119360291 3.117734646 0.816066081 1 10.0605094 -4.250445145 3.586741731 0.932760253 3.396498358 0.977957846 0.098764573 0.028889858 0.648901123 0.013321437 0.193082559 5.62E-05 4.250445145 2.463738105 up S(ph)PGSSWQEYGPSDTCGSR ddPTM_HeLa_Curcumin_4h_R1 1 SPGSSWQEYGPSDTCGSR 18 0 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 S(0.998)PGS(0.001)S(0.001)WQEYGPSDTCGSR 231.42 9.84E-24 13303000 437.32 335.96 304.41 372.98 321.68 412.79 318.59 0 463.79 411.67 TRUE FALSE FALSE 402.7056605 364.9988854 315.6917024 371.4367076 317.8441761 327.1727009 327.528778 0 412.9133973 425.9755019 0.945372818 0.856854171 0.741102953 0.871967299 0.746155999 0.768055204 0.768891114 0 0.969336019 1 8.734626652 -4.323938666 3.10919665 0.911883417 1.86E-44 0.86420645 0.0999405 0.094574446 1.434033439 0.017276622 0.192272495 4.74E-05 4.323938666 -0.911883417 down MSSPEDDSDTK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 MSSPEDDSDTKR 12 1 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 0 1 MSSPEDDSDTK(1)R 98.898 0.00059178 0 0 188.49 152.55 102.15 257.28 314.33 227.09 46.584 177.04 150.95 FALSE TRUE FALSE 0 204.7822357 158.2036372 101.7273304 254.212104 249.1344148 233.4615342 60.78724715 157.6191549 156.1955013 0 1.311063597 1.012856554 0.651282076 1.627525133 1.595016583 1.49467515 0.389174123 1.009114563 1 7.287209091 -7.236390538 24.41680092 0.527777739 1.177928319 0.166179665 0.464125017 589.6849994 574806.3189 0.08627 0.105632617 5.80E-08 7.236390538 0.65015058 MSY(ph)QS(ph)SSTEERR ddPTM_HeLa_Curcumin_4h_R1 1 MSYQSSSTEERR 12 1 Q02383 Q02383 SEMG2 Semenogelin-2 2 0 MS(0.382)Y(0.62)QS(0.827)S(0.087)S(0.082)T(0.003)EERR 45.357 0.009379 0 1042.7 975.73 1043.9 1034.1 845.82 1155.6 703.72 1167 1250.2 1466.3 TRUE FALSE FALSE 960.1691947 1060.067753 1082.587852 1029.821168 835.7341489 915.9155337 723.4644892 1522.812928 1113.056188 1517.253816 0.6328336 0.698675292 0.713517963 0.678740206 0.550820265 0.603666654 0.476824959 1.00366393 0.733599202 1 10.56724673 -9.299892615 0.662062385 1.044770501 0.653420771 0.104743985 0.155178542 0.650501807 0.420224968 0.149958069 0.02653283 5.01E-10 9.299892615 -0.39134973 MT(ph)T(ph)RT(ph)PVTPRK ddPTM_HeLa_Curcumin_4h_R1 1 MTTRTPVTPRK 11 2 J3QLE7 J3QLE7 LRRC37B 3 0 MT(0.883)T(0.907)RT(0.883)PVT(0.327)PRK 53.751 0.0087879 0 1082.5 1004.8 1040.5 1034.3 920.77 878.54 815.64 945.78 1412.6 882.26 TRUE FALSE FALSE 996.8189828 1091.650435 1079.061845 1030.020341 909.7904191 696.3209008 838.5246632 1234.143968 1257.641314 912.9184693 1.091903621 1.195780863 1.181991472 1.128271993 0.996573571 0.762741608 0.918509912 1.351866579 1.377605292 1 9.834342212 -5.629828484 7.87128127 1.073835233 0.981852404 0.024944505 0.177916018 0.522103859 34.88977936 0.022163589 0.044430247 2.35E-06 5.629828484 -0.091982829 MT(ph)VMSLSRDLK ddPTM_HeLa_Curcumin_4h_R1 1 MTVMSLSRDLK 11 1 D6R9J6;D6RAC4;D6RC86;D6RGK1;D6R9U6;D6RHD1;D6RJE1;D6RE69;D6R9I1;A0A1B0GV48;D6RBC4;Q8NAP3 D6R9J6 ZBTB38 Zinc finger and BTB domain-containing protein 38 1 0 MT(0.974)VMS(0.026)LSRDLK 86.189 0.006521 14164000 3133.8 2379.4 2792.1 2707.3 2861.5 3151.1 2413.8 2433.8 2957.4 2308.8 TRUE FALSE FALSE 2885.756423 2585.064734 2895.577682 2696.09791 2827.378481 2497.52634 2481.524732 3175.854416 2632.980619 2389.030628 1.207919392 1.08205592 1.212030373 1.128532166 1.183483564 1.045414115 1.038716165 1.329348556 1.102112542 1 11.22220963 -9.453676714 1.135903812 0.998319697 1.15174759 0.1410883 0.088301306 0.470745061 1.067209028 0.057989994 0.013752919 3.52E-10 9.453676714 0.153427893 MTDQEAIQDLWQWR ddPTM_HeLa_Curcumin_4h_R1 12 MTDQEAIQDLWQWR 14 0 P06748;P06748-2 P06748 NPM1 Nucleophosmin 0 0 ;;;;;;;;;;; ;;;;;;;;;;; 259.18 2.55E-38 1740869200 15331.66 12096.49 12787.67 12003.09 12737.14 24593.59 17454.61 15562.26 15903.61 13941.611 FALSE FALSE TRUE 14118.14293 13142.05669 13261.5923 11953.42439 12585.25792 19492.60221 17944.33938 20307.12143 14159.02377 14426.08094 0.978654077 0.910992857 0.919278933 0.828598179 0.872396181 1.351205659 1.243881789 1.407667232 0.981487892 1 13.8163918 -5.255634189 24.99843229 0.959008495 1.32521461 0.883129117 0.067121589 136.2441172 586694.9521 0.010690771 0.026471761 5.55E-06 5.255634189 0.366206114 MTEEEVEMLVAGHEDS(ph)NGCINYEELVR ddPTM_HeLa_Curcumin_4h_R1 2 MTEEEVEMLVAGHEDSNGCINYEELVR 27 0 P60660-2;G8JLA2;F8VZU9;F8W180;F8VXL3 P60660-2 MYL6 Myosin light polypeptide 6 1 0 MT(0.025)EEEVEMLVAGHEDS(0.973)NGCINY(0.002)EELVR;MTEEEVEMLVAGHEDS(1)NGCINYEELVR ; 128.35 1.11E-08 17622300 1642.61 1473.04 1658.57 1423.26 1736.38 2280.49 1515.61 1910.04 1957.97 1980.74 TRUE FALSE FALSE 1512.595685 1600.363014 1720.038063 1417.370927 1715.674803 1807.490668 1558.133938 2492.402403 1743.18559 2049.570568 0.738006151 0.780828452 0.839218757 0.691545317 0.837089891 0.881887502 0.760224587 1.21606079 0.850512599 1 11.00110595 -4.253231832 24.5330683 0.844784402 1.21606103 0.6541899 0.084685341 533.0723354 1593351.549 0.015760832 0.234684968 5.58E-05 4.253231832 0.371276628 MTEEEVEMLVAGHEDSNGCINYEELVR ddPTM_HeLa_Curcumin_4h_R1 1 MTEEEVEMLVAGHEDSNGCINYEELVR 27 0 P60660-2;G8JLA2;F8VZU9;F8W180;F8VXL3 P60660-2 MYL6 Myosin light polypeptide 6 0 0 81.888 0.00016472 424810 0 194.99 87.34 210.45 214.34 0 0 0 0 81.861 FALSE FALSE TRUE 0 211.8440667 90.57689723 209.5792137 211.7841355 0 0 0 0 84.70566366 0 2.500943356 1.069313353 2.474205438 2.500235832 0 0 0 0 1 6.40438653 MTGLVDEAIDT(ph)KSLLDASEEAIKK ddPTM_HeLa_Curcumin_4h_R1 1 MTGLVDEAIDTKSLLDASEEAIKK 24 2 P18206;P18206-2 P18206 VCL Vinculin 1 0 MT(0.013)GLVDEAIDT(0.55)KS(0.431)LLDAS(0.006)EEAIKK 41.256 0.017077 152080000 2057.4 1160.3 1730.5 1845.4 1598.4 2255.4 1457 1644.9 1679.3 1715.2 TRUE FALSE FALSE 1894.554619 1260.591162 1794.633852 1837.764224 1579.340124 1787.604616 1497.879499 2146.422438 1495.084991 1774.803072 1.067473146 0.710271005 1.01117351 1.035475007 0.88986781 1.007212938 0.843969408 1.209386253 0.842394863 1 10.79344324 MTGSPT(ph)LVK ddPTM_HeLa_Curcumin_4h_R1 1 MTGSPTLVK 9 0 B7ZBM3;Q8IVH2-3;Q8IVH2-2;Q8IVH2 B7ZBM3 FOXP4 Forkhead box protein P4 1 0 MT(0.001)GS(0.059)PT(0.94)LVK 121.83 0.016702 24736000 3938.2 2774.8 2853.7 3582.4 3128.6 3864 4172.6 3041.8 4141 3147.9 TRUE FALSE FALSE 3626.487314 3014.641348 2959.460632 3567.576978 3091.293488 3062.562844 4289.671926 3969.230817 3686.74266 3257.289291 1.113345175 0.925506174 0.908565488 1.095259481 0.949038668 0.940218252 1.316945332 1.218568713 1.131843791 1 11.66945614 -4.756384881 24.99998776 1.024541911 1.267757092 0.616113959 0.081186125 64.31171378 318080.0447 0.011529574 0.040596656 1.75E-05 4.756384881 0.243215181 MTIS(ph)QQEFGR ddPTM_HeLa_Curcumin_4h_R1 1 MTISQQEFGR 10 0 H0Y3Y9;P55036;Q5VWC4 H0Y3Y9;Q5VWC4 PSMD4 26S proteasome non-ATPase regulatory subunit 4 1 0 MT(0.003)IS(0.997)QQEFGR 92.792 0.017361 14629000 1184.5 846.02 1228.4 1108.6 1179.3 1556 1119 2005.6 1593.9 1284.2 TRUE FALSE FALSE 1090.745575 919.146199 1273.925585 1104.012907 1165.237618 1233.26806 1150.396128 2617.098207 1419.053158 1328.825854 0.820834101 0.69169801 0.958685128 0.830818352 0.876892645 0.92808855 0.86572377 1.969481703 1.067900021 1 10.37593633 -4.260593261 24.98915417 0.891948588 1.969482042 0.913882256 0.099097319 13.65171826 403118.3991 0.013298671 0.10778103 5.49E-05 4.260593261 1.077533453 MTNNEDS(ph)LSPTSSTLSNLELDAAEKDR ddPTM_HeLa_Curcumin_4h_R1 2 MTNNEDSLSPTSSTLSNLELDAAEKDR 27 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 0 MT(0.014)NNEDS(0.448)LS(0.448)PT(0.082)S(0.007)STLSNLELDAAEKDR;MT(0.008)NNEDS(0.245)LS(0.245)PT(0.245)S(0.245)S(0.01)T(0.004)LSNLELDAAEKDR ; 67.01 0.0013008 57594000 3117.4 2889.8 2947.6 2862.6 2785.3 3189.6 2232.8 4742.4 3308.2 2874.5 TRUE FALSE FALSE 2870.654501 3139.581435 3056.840649 2850.75532 2752.087117 2528.041006 2295.446359 6188.335929 2945.298737 2974.388661 0.965124208 1.055538396 1.02772065 0.958434033 0.925261434 0.849936338 0.771737194 2.080540452 0.990219864 1 11.53837746 -4.255324191 24.99966726 0.965916842 2.080540941 0.945321552 0.081529637 114.3403681 467424.7853 0.011730437 0.144610913 5.55E-05 4.255324191 1.114624099 MTNNEDSLS(ph)PTSSTLSNLELDAAEKDR ddPTM_HeLa_Curcumin_4h_R1 1 MTNNEDSLSPTSSTLSNLELDAAEKDR 27 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 0 MT(0.003)NNEDS(0.23)LS(0.63)PT(0.111)S(0.023)S(0.002)TLSNLELDAAEKDR 129.08 4.72E-08 90375000 2253.3 1752.7 2342.2 2094.8 1689.4 2404.3 1897.9 2819.5 2434.9 2332 TRUE FALSE FALSE 2074.948927 1904.195578 2429.003992 2086.132273 1669.255008 1905.621078 1951.149966 3679.152571 2167.797562 2413.036826 0.859891115 0.789128271 1.006617042 0.864525667 0.691765244 0.78971902 0.8085869 1.524698061 0.898369034 1 11.23663422 -4.256851767 24.82521091 0.89118036 1.524698344 0.805847354 0.097059587 167.408267 905870.4455 0.015707673 0.168347467 5.54E-05 4.256851767 0.633517984 MTS(ph)EEMT(ph)AS(ph)VLIPVT(ph)QR ddPTM_HeLa_Curcumin_4h_R1 1 MTSEEMTASVLIPVTQR 17 0 Q9P212 Q9P212 PLCE1 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1" 4 0 MT(0.46)S(0.541)EEMT(1)AS(1)VLIPVT(1)QR 65.225 0.007391 8578200 0 0 106.83 0 109.31 141.01 0 99.806 63.185 197.78 TRUE FALSE FALSE 0 0 110.7892138 0 108.0065496 111.7629365 0 130.2363899 56.25376358 204.6528403 0 0 0.541351948 0 0.527754951 0.546109872 0 0.636377144 0.274874092 1 7.677034879 -9.420383081 1.144787548 1.00061722 0.255047794 0 0.3351467 0.294545694 0.689541856 0.173936733 0.043726151 3.80E-10 9.420383081 -0.745569426 MTTIS(ph)LT(ph)PSNS(ph)NT(ph)PLK ddPTM_HeLa_Curcumin_4h_R1 1 MTTISLTPSNSNTPLK 16 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 4 0 MT(0.023)T(0.026)IS(0.95)LT(0.87)PS(0.239)NS(0.915)NT(0.976)PLK 62.055 0.0074896 0 954.63 666.76 664.13 827.39 1044.4 1493.6 1594.3 945.98 997.09 678.95 TRUE FALSE FALSE 879.0700282 724.3917634 688.743242 823.9664794 1031.946212 1183.810524 1639.031767 1234.404947 887.7117216 702.543462 1.251267823 1.031098861 0.980356774 1.17283346 1.468871704 1.685035286 2.332996969 1.757051363 1.263568405 1 9.456443668 -5.325508611 1.667182098 1.104408926 2.041728521 0.820660628 0.171924471 0.105131781 0.554658694 0.024821014 0.081597232 4.73E-06 5.325508611 0.937319595 MVEMLEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 MVEMLEKK 8 1 Q9NWT1 Q9NWT1 PAK1IP1 p21-activated protein kinase-interacting protein 1 0 1 MVEMLEK(1)K 75.189 0.017694 0 227.4 255.31 398.63 333.2 328.64 271.32 231.22 250.89 377.03 428.12 FALSE TRUE FALSE 209.40105 277.3778588 413.4035785 331.8213067 324.7211826 215.0451736 237.7074109 327.385206 335.6707523 442.9971381 0.472691654 0.626139166 0.933196951 0.749037134 0.733009662 0.485432422 0.536589044 0.739023298 0.757726684 1 8.791153568 -9.51588408 1.264006846 1.000337973 0.641059749 0.186604762 0.151583457 0.340352482 0.972036403 0.105186197 0.025220257 3.05E-10 9.51588408 -0.359278225 MVEPENAVTITPLRPEDDYS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 MVEPENAVTITPLRPEDDYSPR 22 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;A0A669KAX5;H0YDF9 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 MVEPENAVTITPLRPEDDY(0.033)S(0.967)PR 93.104 0.00011488 22982000 1503.2 1393.8 1283.8 1824.3 1361.8 1603.8 930.87 782.38 1810.4 1623.6 TRUE FALSE FALSE 1384.220134 1514.273861 1331.378757 1816.75153 1345.561424 1271.153801 956.9877069 1020.92406 1611.803649 1680.019979 0.823930757 0.90134277 0.792477931 1.08138686 0.800919894 0.756630169 0.569628766 0.607685666 0.959395525 1 10.71426267 -5.087140679 1.853174252 0.913016558 0.583652805 0.702900338 0.084232811 0.163564149 1.060526785 0.013542347 0.052866383 8.18E-06 5.087140679 -0.329363753 MVES(ph)CLGSPCWASPQLLR ddPTM_HeLa_Curcumin_4h_R1 1 MVESCLGSPCWASPQLLR 18 0 Q9Y4W2-3;Q9Y4W2-2;Q9Y4W2 Q9Y4W2-3 LAS1L Ribosomal biogenesis protein LAS1L 1 0 MVES(0.602)CLGS(0.39)PCWAS(0.008)PQLLR 83.499 0.0051679 11072000 2718 2209.5 2439.7 2785.9 2719 2756.4 2329.8 1915.4 2481.2 2367.8 TRUE FALSE FALSE 2502.867432 2400.479335 2530.117428 2774.372684 2686.577701 2184.691569 2395.167918 2499.396643 2209.018568 2450.080874 1.021544823 0.979755142 1.032666903 1.132359635 1.096526131 0.89168141 0.977587288 1.020128221 0.90161047 1 11.25861366 -5.261750721 24.99999986 1.02416369 0.964577809 0.150412354 0.065700935 36.05794732 2895543.984 0.008075197 0.019184574 5.47E-06 5.261750721 -0.05958588 MVFETGQFDDAED ddPTM_HeLa_Curcumin_4h_R1 1 MVFETGQFDDAED 13 0 Q9NQ92;H9KV77 Q9NQ92 COPRS Coordinator of PRMT5 and differentiation stimulator 0 0 147.4 0.0056856 10389000 5808.8 4610 5372.3 5091.2 4871 6671.4 4710.9 5110.2 5504 5050.8 FALSE FALSE TRUE 5349.027351 5008.467858 5571.402164 5070.133963 4812.916506 5287.676438 4843.075175 6668.276456 4900.22497 5226.314924 1.023479723 0.958317272 1.066028788 0.970116428 0.920900592 1.011740876 0.926671134 1.275904065 0.937606142 1 12.35157834 -4.252161135 24.81289581 0.998517737 1.275904227 0.769787541 0.047620572 366.9920539 981427.519 0.005822416 0.096287279 5.60E-05 4.252161135 0.27738649 MVHGVYK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 MVHGVYKK 8 1 O95139-2;O95139 O95139-2 NDUFB6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 0 1 MVHGVYK(1)K 70.268 0.013057 635350 620.58 794.83 731.95 775.48 774.68 773.36 649.81 620.38 805.62 676.38 FALSE TRUE FALSE 571.4604382 863.5315635 759.0767109 772.2712692 765.442447 612.9564184 668.0419197 809.5310061 717.2455016 699.8841547 0.816507181 1.233820708 1.084574791 1.10342728 1.093670205 0.875796965 0.954503564 1.156664286 1.024806029 1 9.450972336 -7.280604933 24.98706455 0.913350617 1.062282561 0.196105732 0.108263825 811.6174357 1058142.55 0.019916936 0.022792608 5.24E-08 7.280604933 0.148931944 LLSISGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 LLSISGKR 8 1 P06748;P06748-3;P06748-2;E5RI98 P06748 NPM1 Nucleophosmin 0 1 LLSISGK(1)R 137.9 0.00030236 61120000 4126.5 3036.1 3859.3 3162.9 4168.8 5003 5236.7 5697.6 3533.6 3058.9 FALSE TRUE FALSE 3799.883171 3298.526955 4002.329053 3149.812758 4119.089783 3965.321405 5383.627708 7434.772011 3145.972921 3165.196547 1.200520446 1.042123895 1.264480418 0.995139705 1.301369353 1.252788364 1.700882592 2.348913219 0.993926561 1 11.62807937 -3.91692876 0.933262445 1.100011149 3.870917682 0.938322326 0.09984878 0.579406433 0.247643735 0.015542545 1.889215751 0.00012108 3.91692876 2.770906534 up MVIQGPS(ph)SPQGEAMVTDVLEDQK ddPTM_HeLa_Curcumin_4h_R1 1 MVIQGPSSPQGEAMVTDVLEDQK 23 0 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 MVIQGPS(0.5)S(0.5)PQGEAMVTDVLEDQK 79.663 0.00028183 0 3167.6 2890.5 3418.2 3072.9 3701.6 3467.2 3358.6 2975.4 2860.9 2492.4 TRUE FALSE FALSE 2916.881118 3140.34194 3544.881499 3060.185154 3657.460838 2748.063637 3452.833277 3882.585763 2547.066428 2579.010714 1.131007755 1.217653701 1.374512126 1.186573261 1.418164266 1.065549523 1.338820834 1.505455461 0.987613744 1 11.33260205 -1 0.048303085 0.363168945 2.80619179 0.570363679 0.112385806 243.8876043 0.899991005 11.15752661 45.28804541 0.1 1 2.443022844 MVIQGPS(ph)SPQGEAMVTDVLEDQKEGR ddPTM_HeLa_Curcumin_4h_R1 3 MVIQGPSSPQGEAMVTDVLEDQKEGR 26 1 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 MVIQGPS(0.497)S(0.497)PQGEAMVT(0.005)DVLEDQKEGR;MVIQGPS(0.49)S(0.49)PQGEAMVT(0.02)DVLEDQKEGR;MVIQGPS(0.487)S(0.487)PQGEAMVT(0.027)DVLEDQKEGR ;; 84.025 2.14E-05 1001920000 8828.4 6628.6 7407.8 8288.9 7558.7 7956.8 5915.54 5344.35 9085.3 7934.6 TRUE FALSE FALSE 8129.622824 7201.546648 7682.339585 8254.602728 7468.567439 6306.469988 6081.514132 6973.817713 8088.66532 8210.326759 0.990170436 0.877132769 0.935692307 1.005392717 0.909655323 0.768114373 0.740715237 0.849395879 0.9851819 1 13.00322393 -5.430263135 3.253953242 0.980814496 0.781625223 0.750927416 0.045558709 0.087801321 1.764016381 0.007067827 0.016797969 3.71E-06 5.430263135 -0.199189273 MVLMWT(ph)S(ph)GDAFK ddPTM_HeLa_Curcumin_4h_R1 1 MVLMWTSGDAFK 12 0 Q8N2U9-2;Q8N2U9 Q8N2U9-2 PQLC1 PQ-loop repeat-containing protein 1 2 0 MVLMWT(1)S(1)GDAFK 42.317 0.020118 10499000 2978 3504.4 3510.8 2954.4 2789 3249.2 3184.5 1948.6 3347.9 5079.6 TRUE FALSE FALSE 2742.288158 3807.304721 3640.913336 2942.175476 2755.742997 2575.279294 3273.848499 2542.71917 2980.643746 5256.115722 0.521732835 0.724357096 0.692700376 0.55976231 0.52429268 0.489958637 0.622864616 0.483763925 0.567081074 1 12.35978132 -10.00250635 0.43914008 1.270824085 0.557076748 0 0.1575386 1.14410074 0.186895538 0.403054436 0.022810911 9.94E-11 10.00250635 -0.713747337 MVMSSY(ph)MVNS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 MVMSSYMVNSK 11 0 P09016 P09016 HOXD4 Homeobox protein Hox-D4 2 0 MVMS(0.176)S(0.203)Y(0.829)MVNS(0.792)K 63.624 0.014995 60760000 2371.4 2705.1 2694.5 2516.1 1816.6 2466.5 2439 2096.3 2686.7 3258.9 TRUE FALSE FALSE 2183.701188 2938.91679 2794.36054 2505.689045 1794.938231 1954.920097 2507.431776 2735.45222 2391.975732 3372.146532 0.647570076 0.871527012 0.828659287 0.743054615 0.532283581 0.579725726 0.743571417 0.8111902 0.709333271 1 11.71945151 -9.512298945 0.727779721 1.048649607 0.709800928 0 0.136719425 0.723970867 0.51917788 0.160711052 0.022447957 3.07E-10 9.512298945 -0.338848679 MVNHFIAEFK ddPTM_HeLa_Curcumin_4h_R1 2 MVNHFIAEFK 10 0 P11142;E9PKE3;P11142-2;E9PN89;A8K7Q2 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 ; ; 106.62 0.007234 11126800 9966.8 7251.2 8592.9 6516.4 7519.1 19788.6 13961 12670.8 8857.6 8656.4 FALSE FALSE TRUE 9177.917263 7877.961417 8911.360433 6489.436863 7429.439643 15684.2213 14352.70809 16534.06859 7885.943441 8957.209256 1.024640265 0.879510704 0.99488135 0.724493163 0.829436874 1.751016511 1.602363825 1.845895091 0.880401832 1 13.1288336 -5.256443088 24.99326008 0.967834156 1.720019067 0.916044665 0.113778579 92.20829266 461257.1357 0.016848386 0.041526518 5.54E-06 5.256443088 0.752184911 MVQEAEK(ac)YK ddPTM_HeLa_Curcumin_4h_R1 1 MVQEAEKYK 9 1 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65;E9PM13;A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 P11142;A0A0G2JIW1 HSPA8;HSPA1B;HSPA1A Heat shock cognate 71 kDa protein;Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 1 MVQEAEK(1)YK 87.806 0.010513 0 214.24 313.99 318.73 222.56 249.4 404.23 280.19 299.88 353.74 284.75 FALSE TRUE FALSE 197.2826779 341.1298965 330.5424142 221.6391057 246.4260679 320.3881414 288.0513773 391.3120315 314.935607 294.6450413 0.669560489 1.157765612 1.121832605 0.752224116 0.83634894 1.087369874 0.97762167 1.328079474 1.06886444 1 8.202834176 -1.000001024 0.685297051 0.877433059 50.20618999 0.222973209 0.166695265 218.3300755 1.145208347 0.030467791 16485.12141 0.099999764 1.000001024 49.32875693 MVQQLQEDVDMEDAP ddPTM_HeLa_Curcumin_4h_R1 2 MVQQLQEDVDMEDAP 15 0 Q9UHA3 Q9UHA3 RSL24D1 Probable ribosome biogenesis protein RLP24 0 0 ; ; 133.02 0.0056764 9780500 4815 4444.3 4619.9 4965.6 4853 5815.5 4973.8 3856.7 5269.2 4425.6 FALSE FALSE TRUE 4433.887669 4828.445489 4791.117558 4945.053663 4795.131145 4609.299746 5113.351442 5032.590076 4691.181943 4579.389271 0.968226855 1.054386339 1.046235049 1.079850035 1.047111495 1.006531542 1.116601175 1.098965338 1.024412136 1 12.16093949 -7.190654566 5.314663816 0.98502991 1.063917382 0.464861594 0.032024458 0.114805915 6.141910856 0.005229266 0.006404389 6.45E-08 7.190654566 0.078887472 MVSQSQPGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 3 MVSQSQPGSR 10 0 E3W994;J3KR49;O75122;E7ERI8;E7EW49;O75122-3 E3W994 CLASP2 CLIP-associating protein 2 1 0 MVSQSQPGS(1)R;MVSQSQPGS(1)R;MVSQSQPGS(1)R ;; 115.92 0.0052731 93048000 6156.7 4966.8 4691.3 5663.4 5028.6 5386.4 4118.5 3408.49 6321.8 4633 TRUE FALSE FALSE 5669.390698 5396.10806 4865.163705 5639.966351 4968.637229 4269.199923 4234.054026 4447.72291 5628.314356 4793.996405 1.182602201 1.125597019 1.014845088 1.176464452 1.036429069 0.890530481 0.883199249 0.927769346 1.174033913 1 12.22701311 -5.368957205 3.874882546 1.091625696 0.898498932 0.687285574 0.062772414 0.130959551 3.490915001 0.01100352 0.025997494 4.28E-06 5.368957205 -0.193126764 MVT(ph)GDNINT(ph)ARAIATK ddPTM_HeLa_Curcumin_4h_R1 1 MVTGDNINTARAIATK 16 1 P20020-1;E7ERY9;P20020-4;P20020-6;P20020;P23634-7;P23634;P23634-8;P20020-2;P20020-5;P23634-2;P23634-3;P23634-4;P23634-5;P23634-6 P20020-1 ATP2B1;ATP2B4 Plasma membrane calcium-transporting ATPase 1;Calcium-transporting ATPase;Plasma membrane calcium-transporting ATPase 4 2 0 MVT(1)GDNINT(1)ARAIATK 66.702 0.0098134 928190 559.21 444.16 552.96 517.36 435.82 648.52 515.15 551.73 700.68 454.18 TRUE FALSE FALSE 514.9479384 482.5512113 573.453184 515.2193014 430.6231311 514.0096417 529.6037225 719.9499371 623.817157 469.9627212 1.09572082 1.026786146 1.22020994 1.096298234 0.916292105 1.093724286 1.126905813 1.531929884 1.32737583 1 8.876402512 -4.211896908 2.438071449 1.054448607 1.678826552 0.542518913 0.113919076 0.232617619 1.498556073 0.010862146 0.318023829 6.14E-05 4.211896908 0.624377945 MVVAT(ph)LIVMNCVIVLNVS(ph)QR ddPTM_HeLa_Curcumin_4h_R1 1 MVVATLIVMNCVIVLNVSQR 20 0 A0A3B3IRM1 A0A3B3IRM1 2 0 MVVAT(1)LIVMNCVIVLNVS(1)QR 43.383 0.0090817 0 3460.3 3297.5 3354.9 2980 3240.5 4454.2 3989.2 2499.4 3777.6 3127.8 TRUE FALSE FALSE 3186.413604 3582.521207 3479.235545 2967.66955 3201.859154 3530.348711 4101.126216 3261.455554 3363.206731 3236.490817 0.984527312 1.106915301 1.075002446 0.916940513 0.989299626 1.090795219 1.267152125 1.00771352 1.039152255 1 11.6602147 -5.096243484 4.499011771 1.001973484 1.14618761 0.278872243 0.077232167 0.158702302 5.408093894 0.010141801 0.02754062 8.01E-06 5.096243484 0.144214126 MVVESAYEVIK ddPTM_HeLa_Curcumin_4h_R1 3 MVVESAYEVIK 11 0 A0A5F9ZHM4;P07195;A0A3B3IS95 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 0 ;; ;; 156.83 1.92E-07 4912500 1803.69 1842.7 1754.95 1805.96 2232.77 3174.13 2574.57 1798.38 2542.79 1610.73 FALSE FALSE TRUE 1660.926033 2001.974777 1819.989991 1798.487416 2206.145676 2515.779658 2646.805505 2346.697783 2263.852299 1666.702748 0.996534046 1.201158863 1.091970355 1.079069089 1.32365875 1.509435118 1.588048924 1.407988189 1.358281974 1 10.70278111 -5.637248119 1.611531407 1.020530058 1.521786414 0.580548815 0.130610489 0.08832784 0.458660009 0.012229256 0.031796408 2.31E-06 5.637248119 0.501256356 MWS(ph)GRKLGSSGGWFLRVLGPGGCNT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 MWSGRKLGSSGGWFLRVLGPGGCNTK 26 3 Q9NZJ6 Q9NZJ6 COQ3 "Ubiquinone biosynthesis O-methyltransferase, mitochondrial" 2 0 MWS(0.99)GRKLGS(0.013)S(0.025)GGWFLRVLGPGGCNT(0.972)K 41.749 0.0086125 0 724.17 601.41 599.29 556.27 701.93 928.88 592.92 924.31 733.4 582.52 TRUE FALSE FALSE 666.8511804 653.3932006 621.5002146 553.9683021 693.5599432 736.2198174 609.5557394 1206.127864 652.9478549 602.7625266 1.106324881 1.083997713 1.031086352 0.919049008 1.15063547 1.221409402 1.011270131 2.00100008 1.083258872 1 9.235445918 -4.259656423 24.99938129 1.059539494 2.001000395 0.924214294 0.080169879 30.26527766 424323.5222 0.01155794 0.099335316 5.50E-05 4.259656423 0.941460902 MY(ph)AGNIPIY(ph)K ddPTM_HeLa_Curcumin_4h_R1 2 MYAGNIPIYK 10 0 Q8IWV8-3 Q8IWV8-3 2 0 MY(1)AGNIPIY(1)K;MY(1)AGNIPIY(1)K ; 75.38 0.011212 39528000 6240.3 5017 5812.9 5383.2 6163.4 8503.2 7578.7 5278.4 6024.1 4590.9 TRUE FALSE FALSE 5746.37367 5450.647125 6028.331188 5360.925745 6089.90548 6739.540469 7791.337925 6887.759861 5363.271302 4750.433433 1.209652498 1.147399959 1.26900656 1.12851297 1.281968386 1.418721168 1.640132008 1.449922403 1.129006727 1 12.21384344 -1 0.174858277 0.990078138 3.471684598 0.74512774 0.090737533 19.2419255 0.205489174 0.126509138 12.65847911 0.1 1 2.48160646 MY(ph)LSVLS(ph)LLLS(ph)VFT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 MYLSVLSLLLSVFTK 15 0 A0PJK1-5;A0PJK1-3;A0PJK1-2;A0PJK1;A0PJK1-4 A0PJK1-5 SLC5A10 Sodium/glucose cotransporter 5 4 0 MY(0.773)LS(0.274)VLS(0.954)LLLS(1)VFT(1)K 57.414 0.0084651 0 417.77 287.14 461.43 231.04 285.34 379.89 369.6 403.91 426.58 246.67 TRUE FALSE FALSE 384.7030637 311.9591021 478.5310017 230.0840177 281.9375069 301.0965318 379.9699813 527.0602996 379.7852413 255.2417641 1.507210487 1.222210257 1.874814662 0.901435619 1.104590026 1.179652291 1.488666961 2.064945372 1.487943176 1 7.9957206 -9.378752561 0.995395419 0.989418304 1.40201189 0 0.364022062 0.843778791 1.433500401 0.256959292 0.059717097 4.18E-10 9.378752561 0.412593586 MY(ph)PGRAS(ph)AS(ph)PS(ph)LDVLITLLSLGSNGY(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 MYPGRASASPSLDVLITLLSLGSNGYK 27 1 Q9HD40-3;Q9HD40 Q9HD40-3 SEPSECS O-phosphoseryl-tRNA(Sec) selenium transferase 5 0 MY(0.972)PGRAS(0.968)AS(0.597)PS(0.597)LDVLIT(0.367)LLS(0.373)LGS(0.152)NGY(0.973)K 40.285 0.0083098 0 587.93 401.81 355.96 210.07 404.92 517.75 319.5 380.66 414.89 366.48 TRUE FALSE FALSE 541.3947201 436.540666 369.1521907 209.200786 400.0915935 410.3628138 328.4643101 496.7214817 369.377605 379.2151527 1.427671643 1.151168836 0.973463713 0.551667792 1.055051705 1.082137174 0.866168738 1.309867177 0.974058137 1 8.566872803 -6.80479496 4.725173748 1.20549295 0.957037157 0.093264532 0.216415696 0.248088379 12.23230267 0.037912307 0.051067486 1.57E-07 6.80479496 -0.248455792 MY(ph)SRRS(ph)LY(ph)HS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 MYSRRSLYHSR 11 2 Q9UQ05 Q9UQ05 KCNH4 Potassium voltage-gated channel subfamily H member 4 4 0 MY(0.603)S(0.399)RRS(0.998)LY(0.999)HS(1)R 42.797 0.0096203 0 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 MYASVLLITAMS(ph)LDR ddPTM_HeLa_Curcumin_4h_R1 1 MYASVLLITAMSLDR 15 0 G3V4Q5 G3V4Q5 LTB4R 1 0 MYASVLLIT(0.004)AMS(0.996)LDR 125.68 0.0010444 142460000 3165.5 2839.9 2918.1 3316.2 3038 3684.5 2785.5 2937.2 3399.9 3050 TRUE FALSE FALSE 2914.947335 3085.368302 3026.247353 3302.478443 3001.773834 2920.293167 2863.653633 3832.738759 3026.939476 3155.987273 0.923624553 0.97762381 0.958890861 1.046416908 0.951136229 0.925318423 0.90737173 1.214434162 0.959110166 1 11.62387567 -4.253534363 24.7644721 0.963081701 1.214434302 0.796186174 0.038447054 318.7252069 998461.1178 0.00590955 0.086010966 5.58E-05 4.253534363 0.251352601 MYEEHLK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 MYEEHLKR 8 1 P84090;G3V279 P84090 ERH Enhancer of rudimentary homolog 0 1 ; MYEEHLK(1)R;MYEEHLK(1)R 112.41 0.0011064 6648000 3584.3 4888.1 3369.2 3838.4 6272 8944.3 7000 6985.7 9080.6 4122 FALSE TRUE FALSE 3300.598873 5310.605583 3494.065516 3822.517718 6197.210496 7089.151357 7196.40116 9115.607772 8084.480899 4265.239193 0.773836759 1.245089746 0.819195679 0.896202427 1.452957317 1.66207592 1.687221006 2.137185597 1.895434355 1 12.05841093 -5.264521821 1.030703042 0.904284163 2.026518034 0.404310524 0.3529748 0.168129301 0.300039283 0.026757062 0.139621221 5.44E-06 5.264521821 1.122233871 TAS(ph)GSSVTSLDGTR ddPTM_HeLa_Curcumin_4h_R1 1 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 0 TAS(0.999)GS(0.001)SVTSLDGTR 107.46 0.0033569 257150000 1589.1 1777.9 1551.1 1499.8 1814.2 2276.2 1943.8 4526.6 1958.3 1569.1 TRUE FALSE FALSE 1463.321058 1931.573754 1608.58513 1493.594225 1792.56685 1804.090462 1998.337797 5906.739502 1743.479389 1623.626108 0.901267263 1.189666601 0.990736181 0.919912668 1.104051506 1.11114896 1.230786932 3.637992437 1.073818277 1 10.66500373 -4.250264896 3.522842012 0.991582223 3.988773189 0.985573655 0.093769845 0.026404264 0.558895763 0.014330412 0.212166932 5.62E-05 4.250264896 2.997190966 up MYGISLCQAILDETKGDYEK ddPTM_HeLa_Curcumin_4h_R1 2 MYGISLCQAILDETKGDYEK 20 1 P04083 P04083 ANXA1 Annexin A1 0 0 ; ; 135.27 8.34E-05 20574600 2129.41 1936.24 2025.32 1543.65 1857.78 3091.15 2280.91 2131.35 2497.01 1897.89 FALSE FALSE TRUE 1960.864952 2103.599958 2100.380141 1537.262785 1835.627187 2450.010646 2344.906196 2781.188803 2223.09425 1963.841536 0.998484305 1.071165834 1.069526284 0.782783517 0.934712477 1.247560254 1.194040432 1.416198177 1.132013052 1 10.93946281 -5.192504792 5.157026976 0.98990192 1.283197043 0.621808522 0.102772011 0.097605465 4.997465162 0.012974899 0.033845628 6.42E-06 5.192504792 0.293295124 MYPESTTGS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 1 MYPESTTGSPAR 12 0 A0A590UJ15;A0A590UJK5;A0A5F9UN28;A0A590UJJ4;K7EKU4;K7EIR5;A0A590UJU4;Q5TG84;A0A590UJU1;A0A590UJY1;A0A590UK89;Q5TG78;A0A590UJX9;A0A590UJV4;A0A590UJ72;A0A590UJI8;Q13303-2;Q13303;Q13303-5 A0A590UJ15 KCNAB2 Voltage-gated potassium channel subunit beta-2 1 0 MYPESTT(0.004)GS(0.996)PAR 206.74 4.43E-09 83758000 1015.4 916.17 1012 953.82 900.77 1414.3 750.48 677.79 1179.3 1078.6 TRUE FALSE FALSE 935.0300186 995.3596524 1049.50561 949.8733456 890.0289061 1120.958238 771.536449 884.4450508 1049.93374 1116.08127 0.837779509 0.891834385 0.940348735 0.851079013 0.797458868 1.004369725 0.691290563 0.792455778 0.940732336 1 10.12422637 -13.52287875 0.152214497 1.553287019 0.79552237 0.300541487 0.07923965 55.10759365 0.569179548 9.20025903 0.17508893 3.00E-14 13.52287875 -0.757764649 MYQGHMQVVGVT(ph)LK ddPTM_HeLa_Curcumin_4h_R1 1 MYQGHMQVVGVTLK 14 0 Q8IYB4-2 Q8IYB4-2 1 0 MYQGHMQVVGVT(1)LK 61.65 0.0095665 0 709.98 519.04 769.19 706.96 720.57 763.22 630.39 281.54 804.22 688.81 TRUE FALSE FALSE 653.7843338 563.9035048 797.696858 704.0347868 711.9776734 604.9195687 648.0770468 367.3802499 715.9990781 712.7460962 0.917275222 0.791170247 1.119187972 0.987777822 0.998921884 0.848716776 0.909267761 0.51544337 1.004564012 1 9.477244422 -3.950034039 1.525519498 0.960126904 1.44E-19 0.703773726 0.085772897 1.052333511 1.214324915 0.012033923 1.905058687 0.000112193 3.950034039 -0.960126904 (ac)MDDS(ph)EVESTASILASVK ddPTM_HeLa_Curcumin_4h_R1 1 MDDSEVESTASILASVK 17 0 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62 O60716 CTNND1 Catenin delta-1 1 0 MDDS(0.999)EVESTASILASVK 83.53 0.0040101 2763300 582.43 508.83 523.14 777.36 560.8 1051.2 1015.2 1053.5 851.47 589.58 TRUE FALSE FALSE 536.3300509 552.8109979 542.5280286 774.1434903 554.1128263 833.1692705 1043.68378 1374.7073 758.0658713 610.0678611 0.87913179 0.906146731 0.889291279 1.268946522 0.908280638 1.365699332 1.710766697 2.253367843 1.242592701 1 9.25282592 -4.250227986 0.860931409 0.941654822 3.052963125 0.881600943 0.145881876 0.371247311 0.197993534 0.017011035 0.743841679 5.62E-05 4.250227986 2.111308304 up NAASFPLRS(ph)PQPVCSPAGSEGTPK ddPTM_HeLa_Curcumin_4h_R1 2 NAASFPLRSPQPVCSPAGSEGTPK 24 1 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 1 0 NAAS(0.006)FPLRS(0.994)PQPVCSPAGSEGTPK;NAAS(0.002)FPLRS(0.993)PQPVCS(0.005)PAGSEGTPK ; 90.06 2.64E-05 66987000 3139.7 2448.79 2524.08 3239.77 2834.11 2965.8 1807.15 1071.35 2980.56 2572.91 TRUE FALSE FALSE 2891.189432 2660.452496 2617.624625 3226.36469 2800.315089 2350.659649 1857.853765 1397.999683 2653.600025 2662.318431 1.085966802 0.999299132 0.983212449 1.211862808 1.051833266 0.882937075 0.69783304 0.525106113 0.996725258 1 11.37846742 -4.742405002 1.744833651 1.047543345 0.524648998 0.877668344 0.065792048 0.106783219 0.558757548 0.00985651 0.068063226 1.81E-05 4.742405002 -0.522894347 NADPILISLK ddPTM_HeLa_Curcumin_4h_R1 1 NADPILISLK 10 0 H0YHL7;B4E3S0;Q9ULV4;Q9ULV4-2;Q9ULV4-3 H0YHL7 CORO1C Coronin;Coronin-1C 0 0 117.52 0.0033178 622620 1102.5 572.62 1016.4 735.82 853.57 1207.3 1038.3 866.69 625.96 946.1 FALSE FALSE TRUE 1015.235962 622.1147213 1054.068678 732.7753718 843.3917352 956.8923709 1067.431904 1130.939791 557.2937541 978.9769046 1.037037704 0.635474359 1.076704336 0.748511398 0.861503199 0.977441211 1.090354531 1.155226222 0.569261391 1 9.935131015 -4.668352589 3.173005733 0.961866737 1.143410206 0.086818879 0.183534192 0.327205515 6.278768257 0.019667181 0.092954881 2.15E-05 4.668352589 0.181543469 NADSELMPPPPERGDPPRLS(ph)PDPVAGSAVSQELR ddPTM_HeLa_Curcumin_4h_R1 1 NADSELMPPPPERGDPPRLSPDPVAGSAVSQELR 34 2 Q9BUR4;E9PMG4;E9PMR3 Q9BUR4 WRAP53 Telomerase Cajal body protein 1 1 0 NADSELMPPPPERGDPPRLS(0.889)PDPVAGS(0.082)AVS(0.029)QELR 68.368 6.49E-06 49002000 5354 4418.4 4542.4 4431 3788.8 3928.2 1931.4 2778.2 5336.7 4896.1 TRUE FALSE FALSE 4930.22525 4800.306808 4710.74534 4412.665696 3743.621035 3113.44704 1985.589886 3625.260391 4751.277362 5066.239111 0.973152894 0.947508932 0.929830834 0.870994361 0.738934928 0.614547986 0.391925814 0.715572304 0.937831251 1 12.30669945 -5.647230552 1.264353376 0.982548058 0.539819033 0.823221134 0.077864181 0.109826653 0.343812368 0.011051044 0.03263352 2.25E-06 5.647230552 -0.442729026 NAEAVLQS(ph)PGLSGK ddPTM_HeLa_Curcumin_4h_R1 2 NAEAVLQSPGLSGK 14 0 Q13045;Q13045-3;Q13045-2 Q13045 FLII Protein flightless-1 homolog 1 0 NAEAVLQS(1)PGLSGK;NAEAVLQS(1)PGLSGK ; 199.33 9.09E-07 360540000 14166.2 12430.5 12683.4 13629.3 13070.1 15379.6 12362.9 10436.8 14980.9 13064.3 TRUE FALSE FALSE 13044.93032 13504.93703 13153.45796 13572.90557 12914.24759 12189.6976 12709.7697 13618.93227 13337.53275 13518.28345 0.964984228 0.999012713 0.97301244 1.00404061 0.955317118 0.901719337 0.940191093 1.007445385 0.986629168 1 13.72262435 -5.601232134 6.985756088 0.984711158 0.94554944 0.306439907 0.026695395 0.202324647 14.92704948 0.003960335 0.007962708 2.50E-06 5.601232134 -0.039161718 NAEEES(ph)ESEAEEGD ddPTM_HeLa_Curcumin_4h_R1 2 NAEEESESEAEEGD 14 0 Q7L1Q6-2;Q7L1Q6;Q7L1Q6-4;Q7L1Q6-3;H0Y503 Q7L1Q6-2 BZW1 Basic leucine zipper and W2 domain-containing protein 1 1 0 NAEEES(0.997)ES(0.003)EAEEGD;NAEEES(0.927)ES(0.073)EAEEGD ; 171.62 0.00019929 108017000 13413 9855.4 12013.6 11611.7 10628.7 10828.6 7442.6 6135.6 11698.2 9973.6 TRUE FALSE FALSE 12351.3469 10707.25686 12458.83458 11563.65386 10501.95969 8582.626297 7651.419325 8006.316195 10414.93673 10320.18186 1.196814849 1.037506607 1.20723014 1.12048935 1.017613821 0.83163518 0.741403536 0.775792162 1.009181512 1 13.33318077 -5.276475306 2.301190269 1.101494934 0.759567438 0.814924451 0.067075818 0.109841688 1.125715804 0.011949011 0.034731835 5.29E-06 5.276475306 -0.341927496 NAEEESES(ph)EAEEGD ddPTM_HeLa_Curcumin_4h_R1 2 NAEEESESEAEEGD 14 0 Q7L1Q6-2;Q7L1Q6;Q7L1Q6-4;Q7L1Q6-3;H0Y503 Q7L1Q6-2 BZW1 Basic leucine zipper and W2 domain-containing protein 1 1 0 NAEEES(0.232)ES(0.768)EAEEGD;NAEEES(0.001)ES(0.999)EAEEGD ; 220.53 3.96E-14 108805100 10647.7 8371.1 8723 8741 8838 8562.6 5442.9 5930.9 9564.7 8346.7 TRUE FALSE FALSE 9804.92331 9094.660583 9046.282054 8704.832058 8732.612622 6786.62024 5595.613125 7739.204107 8515.47634 8636.747204 1.135256489 1.053019194 1.047417719 1.007883159 1.011099713 0.785784287 0.647884324 0.896078573 0.985958734 1 13.07627235 -5.299806607 3.136247971 1.05837586 0.757410269 0.738936886 0.069674511 0.088380689 1.74995257 0.010464395 0.02699198 5.01E-06 5.299806607 -0.300965591 NAEEESESEAEEGD ddPTM_HeLa_Curcumin_4h_R1 1 NAEEESESEAEEGD 14 0 Q7L1Q6-2;Q7L1Q6;Q7L1Q6-4;Q7L1Q6-3;H0Y503 Q7L1Q6-2 BZW1 Basic leucine zipper and W2 domain-containing protein 1 0 0 169.99 0.0017348 5381600 6011.2 4132.9 3744.6 4119.7 3948.1 3786.5 2093.4 2093.6 4581 3804 FALSE FALSE TRUE 5535.407177 4490.12946 3883.37817 4102.653773 3901.021486 3001.137217 2152.13517 2731.929002 4078.475761 3936.188717 1.406286023 1.14073023 0.98658333 1.042290924 0.991065664 0.762447493 0.546756094 0.694054376 1.03614843 1 11.94258368 -5.405113001 0.924063001 1.18388745 0.574944115 0.705864099 0.12464421 0.330231163 0.479566662 0.027768371 0.135088089 3.93E-06 5.405113001 -0.608943335 CCSGAIIVLTK(ac)SGR ddPTM_HeLa_Curcumin_4h_R1 2 CCSGAIIVLTKSGR 14 1 P14618;P14618-3;B4DNK4 P14618 PKM Pyruvate kinase PKM;Pyruvate kinase 0 1 ; CCSGAIIVLTK(1)SGR;CCSGAIIVLTK(1)SGR 181.98 5.97E-08 5139600 1624.13 1120.85 1257.37 861.8 1312.17 2376.1 1560.36 1871.97 1202.61 1103.68 FALSE TRUE FALSE 1495.578397 1217.73128 1303.969238 858.2340999 1296.52323 1883.270076 1604.139502 2442.725036 1070.686692 1142.032798 1.309575697 1.066283982 1.141796664 0.751496894 1.135276703 1.64905078 1.40463523 2.138927218 0.937527095 1 10.15738837 -3.904512782 0.872258621 1.117077579 3.268789776 0.731179494 0.1970248 1.625741174 0.601641061 0.032372042 3.867655145 0.000124591 3.904512782 2.151712198 up NAEQYK(ac)DQADK ddPTM_HeLa_Curcumin_4h_R1 2 NAEQYKDQADK 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 1 ; NAEQYK(1)DQADK;NAEQYK(1)DQADK 104.22 0.0063744 5768300 4486.4 6398.7 3959.1 4230.5 8951.1 10891.5 8406.8 7062.8 11110.5 4513.8 FALSE TRUE FALSE 4131.296706 6951.775116 4105.827729 4212.995312 8844.363979 8632.480127 8642.672182 9216.215207 9891.705947 4670.654214 0.884522064 1.488394301 0.879069086 0.902013962 1.893602817 1.848237898 1.850420045 1.973217195 2.117841633 1 12.18940893 -5.75870772 24.99944731 0.98119357 1.88536387 0.331953493 0.398246774 18.22885805 166822.6485 0.025360105 0.04895549 1.74E-06 5.75870772 0.9041703 NAEQYKDQADK ddPTM_HeLa_Curcumin_4h_R1 4 NAEQYKDQADK 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ;;; ;;; 131.42 0.00036729 71084000 18094.5 15059.1 16478.3 18253 18519 18726.3 15947.9 15442.7 18984.8 16814.1 FALSE FALSE TRUE 16662.30123 16360.7415 17089.00029 18177.47392 18298.17302 14842.25429 16395.35515 20151.10814 16902.21494 17398.38872 0.957692203 0.940359579 0.982217409 1.044779158 1.05171653 0.853082117 0.942349054 1.158216917 0.971481624 1 14.08666608 -6.503504993 24.21874358 0.975764651 1.001228779 0.057268521 0.075293431 2006.591198 2508401.596 0.01156795 0.017489876 3.14E-07 6.503504993 0.025464128 NAESNAELK ddPTM_HeLa_Curcumin_4h_R1 2 NAESNAELK 9 0 A0A087WXM6;J3QQT2;J3KRX5;A0A0A6YYL6;P18621;P18621-3;J3QLC8;A0A0A0MRF8;P18621-2;J3KRB3;A0A087WWH0;J3QS96 A0A087WXM6 RPL17;RPL17-C18orf32 60S ribosomal protein L17 0 0 ; ; 150.81 2.63E-06 17180500 8120.8 7128.8 7029.5 7179.3 7159.3 9179.2 6654.4 6937.9 6836 7580 FALSE FALSE TRUE 7478.030111 7744.981707 7290.019454 7149.593959 7073.930023 7275.330449 6841.104555 9053.233772 6086.107903 7843.404436 0.95341636 0.98745153 0.929445818 0.911542178 0.901895354 0.927573034 0.872211118 1.154247986 0.775952324 1 12.93726428 -8.789610849 0.613531006 1.001448555 0.946109544 0 0.101506286 1.919300081 1.336891737 0.054168275 0.016810919 1.62E-09 8.789610849 -0.055339011 NAGAVIGK(ac)GGK ddPTM_HeLa_Curcumin_4h_R1 1 NAGAVIGKGGK 11 1 P61978-3;P61978;P61978-2;Q5T6W2;S4R457 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 1 NAGAVIGK(1)GGK 93.111 0.017195 2597800 949.04 1307 1211.7 848.51 1191.5 1627.5 1172 1109.9 1450.9 1271.2 FALSE TRUE FALSE 873.9224826 1419.971256 1256.606668 844.9990904 1177.292141 1289.938154 1204.883166 1448.303401 1291.7399 1315.374105 0.664390822 1.079518937 0.955322644 0.642402102 0.895024568 0.980662573 0.916000369 1.101058166 0.982032332 1 10.36125746 -3.720943736 0.854086411 0.854971705 1.497917063 0.119827438 0.138014928 7.010853559 1.986459238 0.025095687 5.276133898 0.000190132 3.720943736 0.642945358 NAGVEGSLIVEK ddPTM_HeLa_Curcumin_4h_R1 1 NAGVEGSLIVEK 12 0 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 151.98 3.43E-05 2300500 1048 602.64 906.12 1138.7 835.53 1185.6 851.98 1018.6 1060.1 752.73 FALSE FALSE TRUE 965.0496942 654.7295163 939.7016043 1133.988361 825.5668505 939.6931955 875.8842658 1329.166451 943.8096822 778.8873115 1.239010676 0.840595946 1.2064667 1.45590812 1.059931056 1.206455904 1.124532719 1.706493907 1.21174099 1 9.605270806 -4.261146812 24.08113045 1.129220346 1.706494147 0.532144443 0.155674574 8.476747187 697117.1853 0.022027265 0.172183734 5.48E-05 4.261146812 0.5772738 NAIAS(ph)DSEADS(ph)DTEVPK ddPTM_HeLa_Curcumin_4h_R1 1 NAIASDSEADSDTEVPK 17 0 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 2 0 NAIAS(0.98)DS(0.119)EADS(0.842)DT(0.059)EVPK 103.4 0.003838 3808600 4973.9 3653.3 3372.4 3645.2 4621.4 3423.4 2695.4 2917.3 3591 2779.4 TRUE FALSE FALSE 4580.210567 3969.074973 3497.384111 3630.117128 4566.292823 2713.34825 2771.02567 3806.77134 3197.076284 2875.983943 1.592571675 1.380075498 1.216065242 1.262217453 1.587732377 0.943450417 0.963505264 1.323641375 1.111646083 1 11.48983991 -5.233111051 24.88448805 1.305056189 1.065529654 0.2170448 0.200088543 1004.839568 882681.1304 0.035385829 0.090195347 5.85E-06 5.233111051 -0.239526535 NAK(ac)K(ac)K(ac)NNK ddPTM_HeLa_Curcumin_4h_R1 2 NAKKKNNK 8 3 A0A669KB12;Q09472;Q92793;Q92793-2 A0A669KB12;Q92793 EP300;CREBBP Histone acetyltransferase p300;CREB-binding protein 0 3 ; NAK(1)K(1)K(1)NNK;NAK(1)K(1)K(1)NNK 126.41 0.0078126 4771800 2265.3 2142.7 1984.77 1804.03 2200.6 2717.2 1922.05 1160.78 2418.3 1851.44 FALSE TRUE FALSE 2085.999115 2327.90544 2058.327322 1796.565402 2174.359282 2153.622091 1975.97755 1514.696478 2153.01854 1915.777402 1.088852553 1.215123134 1.074408394 0.937773564 1.134974909 1.124150482 1.031423352 0.790643254 1.12383544 1 10.90371423 -4.270804895 4.197173114 1.061556422 0.771220033 0.563225052 0.075411677 0.128764585 5.071206116 0.010826667 0.110300198 5.36E-05 4.270804895 -0.29033639 NALFPEVFS(ph)PTPDENSDQNSR ddPTM_HeLa_Curcumin_4h_R1 3 NALFPEVFSPTPDENSDQNSR 21 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 NALFPEVFS(0.999)PT(0.001)PDENSDQNSR;NALFPEVFS(0.995)PT(0.005)PDENSDQNSR;NALFPEVFS(0.914)PT(0.086)PDENSDQNSR ;; 130.72 7.07E-06 27328300 7808 5956.4 6348.9 7422.4 7500.9 9447.5 6851.4 12737.4 7816.3 6919.9 TRUE FALSE FALSE 7189.988561 6471.244675 6584.195819 7391.688075 7411.456666 7487.982005 7043.631844 16620.97462 6958.871445 7160.36601 1.004137016 0.903758923 0.919533416 1.0323059 1.035066735 1.045754085 0.983697179 2.321246512 0.97185974 1 12.80581762 -4.261111858 24.99999999 0.996187222 2.321246909 0.987324557 0.045296158 2.023119656 154359.6778 0.006425526 0.050280471 5.48E-05 4.261111858 1.325059686 NALLQLTDS(ph)QIADVAR ddPTM_HeLa_Curcumin_4h_R1 1 NALLQLTDSQIADVAR 16 0 O75643 O75643 SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 1 0 NALLQLT(0.185)DS(0.815)QIADVAR 125.51 0.00073011 0 1763.7 1695.6 1465.1 1503.6 1606.3 2304.2 1504.6 1677.5 1590.7 1401.8 TRUE FALSE FALSE 1624.101284 1842.160109 1519.397895 1497.378502 1587.145922 1826.282946 1546.815027 2188.962028 1416.20419 1450.512446 1.119674146 1.270006413 1.047490423 1.032309999 1.094196693 1.259060515 1.066392109 1.509095654 0.976347493 1 10.50234696 -1.520175571 1.08165723 1.078274334 200 0.604666125 0.097752934 385.2215789 1.205438694 0.014500398 189161.6183 0.030187311 1.520175571 198.9217257 NALPPVLTTVNGQS(ph)PPEHSAPAK ddPTM_HeLa_Curcumin_4h_R1 2 NALPPVLTTVNGQSPPEHSAPAK 23 0 Q6PKG0;A0A0B4J210;H0YBM7 Q6PKG0 LARP1 La-related protein 1 1 0 NALPPVLTTVNGQS(1)PPEHSAPAK;NALPPVLTTVNGQS(0.999)PPEHS(0.001)APAK ; 125.98 2.33E-06 2054900000 8722.9 7060.8 7710.7 8438.8 7811.8 9655 6661.2 5411.3 8838.2 8164.8 TRUE FALSE FALSE 8032.473261 7671.10409 7996.465325 8403.882482 7718.649387 7652.444166 6848.095344 7061.180459 7868.671572 8448.526192 0.950754377 0.907981335 0.94649234 0.994715799 0.913608979 0.905772675 0.81056686 0.835788432 0.931366181 1 13.04448398 -1.449174361 0.264932887 0.987871701 1.21E-13 0.6218916 0.035437619 14.15641432 0.22193577 0.016218434 6.142786028 0.035548857 1.449174361 -0.987871701 NANCSLPSCQK(ac)MK ddPTM_HeLa_Curcumin_4h_R1 1 NANCSLPSCQKMK 13 1 A0A669KB12;Q09472;Q92793;Q92793-2 A0A669KB12;Q92793 EP300;CREBBP Histone acetyltransferase p300;CREB-binding protein 0 1 NANCSLPSCQK(1)MK 234.63 5.65E-38 2434700 1704.9 1305.6 1576.5 1299.1 1599.1 1721.5 1438.6 956.13 1296.4 1295.5 FALSE TRUE FALSE 1569.955366 1418.450246 1634.926477 1293.724668 1580.031777 1364.441495 1478.963244 1247.649636 1154.188163 1340.518529 1.17115529 1.058135502 1.219622439 0.965092717 1.178672091 1.017846054 1.103276988 0.930721664 0.861001276 1 10.38857544 -4.257381523 24.22248155 1.085801691 0.930721568 0.094051325 0.105818112 297.656088 1776680.805 0.011399636 0.11444736 5.53E-05 4.257381523 -0.155080123 NAPAAVDEGSIS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 NAPAAVDEGSISPR 14 0 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 0 NAPAAVDEGSIS(1)PR;NAPAAVDEGSIS(1)PR ; 229.92 1.87E-20 790010000 3287.2 2282.3 2711.3 3038.1 2811 3334.9 2525.7 1942.93 2805.1 2552 TRUE FALSE FALSE 3027.014651 2479.571842 2811.783163 3025.529147 2777.480661 2643.204148 2596.564344 2535.320413 2497.387548 2640.68181 1.146300414 0.938989254 1.064794385 1.145737868 1.051804367 1.000955184 0.983293154 0.960100684 0.945735885 1 11.36669476 -5.149974485 2.730313779 1.065340991 0.973897335 0.085899208 0.069217981 0.318748954 4.566547685 0.010071687 0.030387597 7.08E-06 5.149974485 -0.091443656 NAPHPDDDDSCS(ph)INSDPEAK ddPTM_HeLa_Curcumin_4h_R1 1 NAPHPDDDDSCSINSDPEAK 20 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 0 NAPHPDDDDS(0.001)CS(0.634)INS(0.365)DPEAK 128.95 3.63E-05 22457000 6647.1 5256.2 6288 5812.5 6508.6 7220.5 4493.9 3227.7 6290.6 5530.8 TRUE FALSE FALSE 6120.975021 5710.522507 6521.038811 5788.449415 6430.989196 5722.886908 4619.986739 4211.810871 5600.536918 5722.994888 1.069540536 0.997820655 1.139445157 1.011437111 1.123710456 0.999981132 0.807267319 0.735945244 0.978602467 1 12.4825546 -4.737035242 3.139518302 1.043379919 0.749619746 0.820983356 0.050982301 0.06625566 1.303027607 0.006696102 0.029033104 1.83E-05 4.737035242 -0.293760172 NAPHPDDDDSCSINS(ph)DPEAK ddPTM_HeLa_Curcumin_4h_R1 1 NAPHPDDDDSCSINSDPEAK 20 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 0 NAPHPDDDDS(0.04)CS(0.102)INS(0.858)DPEAK 134.56 4.87E-05 20918000 6327.9 4677.3 5888.4 6097.8 6656.3 8158.1 5512.6 3381.1 6222.7 5658.9 TRUE FALSE FALSE 5827.040038 5081.58497 6106.629284 6072.568919 6576.92797 6466.018099 5667.26872 4411.981825 5540.085378 5855.546354 0.995131741 0.867824224 1.042879505 1.037062735 1.123196295 1.104255301 0.967846274 0.753470566 0.946126124 1 12.51558807 -4.285762831 3.954660677 1.009765758 0.735504139 0.555233874 0.069574453 0.12498396 3.9226333 0.009601457 0.093843515 5.18E-05 4.285762831 -0.274261619 NARCTSISWELR ddPTM_HeLa_Curcumin_4h_R1 1 NARCTSISWELR 12 1 H7C2Y2;A0A1W2PPQ7;A0A1W2PPR6;A0A1W2PPS0;A0A1W2PPC3;A0A1W2PP57;A0A1W2PP53;A0A1W2PQ29;A0A1W2PRZ8;A0A1W2PR92;A0A1W2PP13;A0A1W2PRV7;A0A1W2PQN1;A0A1W2PQ52;A0A1W2PRH2;A0A1W2PPI8;A0A1W2PNP0;Q969N2-3;Q969N2-4;Q969N2-6;Q969N2-5;Q969N2 H7C2Y2 PIGT GPI transamidase component PIG-T 0 0 69.01 0.011868 1571700 360.05 622.81 906.8 395.03 508.17 513.83 419.79 249.8 469.44 299.27 FALSE FALSE TRUE 331.5516626 676.6429212 940.4068057 393.3954705 502.1104046 407.2558659 431.5681776 325.9628701 417.9436065 309.6696102 1.070662576 2.185047867 3.036806889 1.270371575 1.621439069 1.315130231 1.393640717 1.052614978 1.349643597 1 8.274585999 -3.277653909 14.67625818 1.323755817 1.375710339 0 0.633707584 0 0 0.09364921 0 0.00052765 3.277653909 0.051954522 SKEFVS(ph)SDESSSGENK ddPTM_HeLa_Curcumin_4h_R1 2 SKEFVSSDESSSGENK 16 1 Q08945 Q08945 SSRP1 FACT complex subunit SSRP1 1 0 SKEFVS(0.853)S(0.085)DES(0.055)S(0.006)S(0.001)GENK;SKEFVS(0.933)S(0.016)DES(0.003)S(0.045)S(0.003)GENK ; 176.21 0.00022827 32507500 5452.4 4551.6 4894.5 4998.3 5149.8 5851.5 3364.2 1255.32 5507.3 5024.3 TRUE FALSE FALSE 5020.836787 4945.020022 5075.894476 4977.618359 5088.391998 4637.83294 3458.590398 1638.061289 4903.162969 5198.894051 0.965750934 0.951167686 0.976341204 0.95743793 0.978745085 0.89208068 0.665255026 0.315078798 0.94311654 1 12.34398904 -4.323891964 1.352655224 0.979628551 0.076370909 0.991475033 0.018895676 0.06737058 0.115808252 0.002771354 0.080323292 4.74E-05 4.323891964 -0.903257642 down NAS(ph)ASFQELEDK ddPTM_HeLa_Curcumin_4h_R1 3 NASASFQELEDK 12 0 F2Z3H0;F2Z3N9;H7C3L7;Q99543-2;Q99543 F2Z3H0 DNAJC2 "DnaJ homolog subfamily C member 2;DnaJ homolog subfamily C member 2, N-terminally processed" 1 0 NAS(0.978)AS(0.022)FQELEDK;NAS(0.977)AS(0.023)FQELEDK;NAS(0.99)AS(0.01)FQELEDK ;; 207.64 3.79E-09 31746900 6585.4 5595.6 6099.9 6175.8 6972 7287.5 6809.7 7322.4 6126.7 5379.7 TRUE FALSE FALSE 6064.158641 6079.25873 6325.96766 6150.246176 6888.863454 5775.990353 7000.761855 9554.966052 5454.616338 5566.644175 1.089374217 1.092086819 1.136405968 1.104839106 1.237525381 1.03760725 1.257626971 1.716467903 0.979875158 1 12.44259215 -1.254623825 0.903240843 1.062975341 199.9999998 0.873248401 0.072190311 129.0912723 0.448806284 0.011554941 52703.98898 0.055638598 1.254623825 198.9370244 NAS(ph)ASFQELEDKK ddPTM_HeLa_Curcumin_4h_R1 1 NASASFQELEDKK 13 1 F2Z3H0;F2Z3N9;H7C3L7;Q99543-2;Q99543 F2Z3H0 DNAJC2 "DnaJ homolog subfamily C member 2;DnaJ homolog subfamily C member 2, N-terminally processed" 1 0 NAS(0.996)AS(0.004)FQELEDKK 102.84 0.0026177 15848000 2834.8 2435.1 3115.5 2615.3 3420.9 3561.2 3364.6 3306.9 2624.7 2397.2 TRUE FALSE FALSE 2610.422589 2645.579193 3230.963171 2604.478582 3380.108002 2822.566977 3459.001621 4315.158587 2336.776977 2480.502522 1.052376511 1.066549689 1.302543796 1.049980219 1.362670657 1.137901273 1.394476156 1.7396308 0.942057892 1 11.27641671 -1 0.364253195 1.021793738 9.57712098 0.779927117 0.108838211 17.00742097 0.210223025 0.027152538 102.5684225 0.1 1 8.555327243 NASCYFDIEWR ddPTM_HeLa_Curcumin_4h_R1 2 NASCYFDIEWR 11 0 Q16658;C9JPH9;C9JFC0;A0A0A0MSB2 Q16658 FSCN1 Fascin 0 0 ; ; 147.62 0.0069205 98255000 2265.6 1583.34 1919.03 2140.4 2265.7 2729.4 2014.31 2159.5 2130.6 2291.3 FALSE FALSE TRUE 2086.275369 1720.196854 1990.15094 2131.543592 2238.683007 2163.291673 2070.826117 2817.921609 1896.87851 2370.922504 0.879942455 0.725539047 0.839399405 0.899035539 0.944224454 0.912426142 0.87342632 1.188533832 0.800059263 1 11.21123279 -4.256331257 24.13322478 0.912362357 1.188534023 0.541445371 0.080174034 227.3746763 1074168.268 0.012055652 0.133239414 5.54E-05 4.256331257 0.276171666 S(ph)LPS(ph)SPLLTHQSISVR ddPTM_HeLa_Curcumin_4h_R1 1 SLPSSPLLTHQSISVR 16 0 J3QQY7;J3KTM5 J3QQY7 TANC2 2 0 S(0.871)LPS(0.565)S(0.565)PLLTHQSISVR 93.106 0.010079 4414200 1031.5 1004.1 841.54 845.8 957.44 1181.5 660.44 320.42 975.05 968.65 TRUE FALSE FALSE 949.8556866 1090.88993 872.7282127 842.3003037 946.0231533 936.4435818 678.9701689 418.114583 868.0894545 1002.310515 0.947666089 1.088375222 0.870716409 0.840358642 0.943842391 0.934284902 0.677405014 0.41715075 0.866088344 1 9.969113809 -4.323832538 1.314673901 0.966655686 0.204533163 0.833303524 0.073259826 0.301062369 0.481963879 0.010017884 0.296467784 4.74E-05 4.323832538 -0.762122523 down NAST(ph)FEDVTQVSS(ph)AY(ph)QK ddPTM_HeLa_Curcumin_4h_R1 1 NASTFEDVTQVSSAYQK 17 0 Q14247;Q14247-3;Q14247-2 Q14247 CTTN Src substrate cortactin 3 0 NAS(0.43)T(0.569)FEDVT(0.001)QVS(0.311)S(0.689)AY(1)QK 92.096 0.0022085 0 1750.8 1550.6 1664.3 2366.7 1767.5 784.53 970.54 1102.8 2013.3 1668.8 TRUE FALSE FALSE 1612.222333 1684.626955 1725.980422 2356.907222 1746.423717 621.8096345 997.7707403 1439.038643 1792.446027 1726.790676 0.933652443 0.97558261 0.999530775 1.364906155 1.011369671 0.360095548 0.577818003 0.833360212 1.038021604 1 10.75387749 -5.282578227 24.49251835 1.00384485 0.589163943 0.629255592 0.157981635 310.3549418 359592.2648 0.022996095 0.051472437 5.22E-06 5.282578227 -0.414680907 NASVYS(ph)PSGPVNR ddPTM_HeLa_Curcumin_4h_R1 1 NASVYSPSGPVNR 13 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 0 NAS(0.001)VYS(0.77)PS(0.229)GPVNR 171.15 0.00019873 25724000 1176 1073 861.42 1008.4 988.29 940.48 620.64 207.42 835.2 671.47 TRUE FALSE FALSE 1082.918359 1165.745339 893.344983 1004.227508 976.5052872 745.4138466 638.053488 270.6614032 743.5806496 694.8035325 1.558596507 1.677805717 1.28575193 1.445340245 1.405440879 1.072841187 0.91832217 0.389550989 1.070202748 1 9.440461279 -4.346546768 1.309693492 1.323600313 0.089183033 0.68982114 0.198688786 0.653505198 1.069626582 0.03738787 1.02700271 4.50E-05 4.346546768 -1.23441728 NATDLQNS(ph)SMSEEELTK ddPTM_HeLa_Curcumin_4h_R1 3 NATDLQNSSMSEEELTK 17 0 Q5QNY5;P40855;H0YJ60;P40855-5 Q5QNY5 PEX19 Peroxisomal biogenesis factor 19 1 0 NATDLQNS(0.466)S(0.466)MS(0.069)EEELTK;NATDLQNS(0.606)S(0.306)MS(0.088)EEELTK;NATDLQNS(0.572)S(0.274)MS(0.154)EEELTK ;; 104.59 0.0017849 73160700 13876.8 11587.8 12624.7 12378.6 12491.4 17473.5 14152.5 8945.3 13898.8 12415.7 TRUE FALSE FALSE 12778.43664 12589.3978 13092.58249 12327.38063 12342.44821 13849.29913 14549.58106 11672.68079 12374.13641 12847.14465 0.994651884 0.979937421 1.019104466 0.959542448 0.960715283 1.078006009 1.132514769 0.908581721 0.963181839 1 13.64916013 -5.259611566 24.99174863 0.992696483 1.048982226 0.157768814 0.05607389 201.8239218 2759524.503 0.007104804 0.017130553 5.50E-06 5.259611566 0.056285743 NATDLQNSS(ph)MSEEELTK ddPTM_HeLa_Curcumin_4h_R1 4 NATDLQNSSMSEEELTK 17 0 Q5QNY5;P40855;H0YJ60;P40855-5 Q5QNY5 PEX19 Peroxisomal biogenesis factor 19 1 0 NATDLQNS(0.077)S(0.805)MS(0.118)EEELTK;NATDLQNS(0.21)S(0.712)MS(0.078)EEELTK;NATDLQNS(0.062)S(0.725)MS(0.213)EEELTK;NATDLQNS(0.164)S(0.672)MS(0.164)EEELTK ;;; 224.36 1.58E-16 278809000 21083.1 17206.5 19459.3 18015.2 17627 27741.7 20842.8 14909.6 19606.9 20540.2 TRUE FALSE FALSE 19414.35039 18693.75319 20180.47878 17940.65788 17416.80954 21987.75871 21427.59287 19455.4684 17456.07212 21253.97042 0.913445818 0.879541696 0.949492183 0.844108537 0.819461456 1.034524763 1.008168942 0.915380422 0.821308762 1 14.37544475 -9.162284382 0.943642151 0.999359379 0.921166683 0 0.083539717 0.816837554 1.325602267 0.042280041 0.012503189 6.88E-10 9.162284382 -0.078192696 NATDLQNSSMS(ph)EEELTK ddPTM_HeLa_Curcumin_4h_R1 1 NATDLQNSSMSEEELTK 17 0 Q5QNY5;P40855;H0YJ60;P40855-5 Q5QNY5 PEX19 Peroxisomal biogenesis factor 19 1 0 NATDLQNS(0.021)S(0.29)MS(0.689)EEELTK 185.63 2.95E-06 58846000 5044.9 4146.5 4785.2 4530.6 4771.6 7015 5216.4 2931.3 5138.7 4666 TRUE FALSE FALSE 4645.590842 4504.904984 4962.543721 4511.853578 4714.701786 5560.009925 5362.758145 3825.039876 4574.997466 4828.143153 0.962189955 0.933051246 1.027836906 0.934490431 0.976504142 1.151583486 1.110728902 0.79223829 0.947568728 1 12.23725274 NAVALS(ph)ASPQLK ddPTM_HeLa_Curcumin_4h_R1 2 NAVALSASPQLK 12 0 A0A2R8YD63;Q92547 A0A2R8YD63 TOPBP1 DNA topoisomerase 2-binding protein 1 1 0 NAVALS(0.654)AS(0.346)PQLK;NAVALS(0.708)AS(0.292)PQLK ; 106.13 0.0067302 10967600 5789.3 4843.9 5333.3 5442.8 5169.4 7812.8 6847.7 2576.9 5052.3 5066.9 TRUE FALSE FALSE 5331.070796 5262.585132 5530.95679 5420.279136 5107.758281 6192.337212 7039.828032 3362.584947 4498.07533 5242.974398 1.016802752 1.003740383 1.054927293 1.033817586 0.974210037 1.181073326 1.342716462 0.641350633 0.857924336 1 12.35616979 -5.302711669 24.96189427 1.011442707 1.083814045 0.010609329 0.173155542 1288.400146 779234.9418 0.021328557 0.047692863 4.98E-06 5.302711669 0.072371338 NAVALSAS(ph)PQLK ddPTM_HeLa_Curcumin_4h_R1 1 NAVALSASPQLK 12 0 A0A2R8YD63;Q92547 A0A2R8YD63 TOPBP1 DNA topoisomerase 2-binding protein 1 1 0 NAVALS(0.047)AS(0.953)PQLK 117.2 0.0038514 88488000 2389 1855.3 1534.4 1869.7 2273.6 3199.6 3064.3 577.58 2622.9 2013.8 TRUE FALSE FALSE 2199.908129 2015.663865 1591.266214 1861.963677 2246.488805 2535.966893 3150.276011 753.6814831 2335.174432 2083.7794 1.055729858 0.967311542 0.763644277 0.893551245 1.078083796 1.217003534 1.511808789 0.36168967 1.120643784 1 11.02498684 -4.23015226 24.2537882 1.036949014 0.361687902 0.544246965 0.191946372 5856.510787 4539860.28 0.026330653 4.833109306 5.89E-05 4.23015226 -0.675261113 NCHTASTTTSS(ph)TPPK ddPTM_HeLa_Curcumin_4h_R1 1 NCHTASTTTSSTPPK 15 0 A0A2R8Y6E3;P81274;H0Y4A4 A0A2R8Y6E3 GPSM2 G-protein-signaling modulator 2 1 0 NCHTASTTT(0.001)S(0.067)S(0.466)T(0.466)PPK 144.08 0.00023665 1581700 1876.6 1398 1216.7 1351.6 1897.3 2587.7 1379.1 388.5 1525.8 1188.4 TRUE FALSE FALSE 1728.06513 1518.836891 1261.791972 1346.007437 1874.675937 2050.981851 1417.793834 506.9518616 1358.423557 1229.696812 1.405277393 1.235131194 1.02610006 1.094584799 1.52450256 1.667876042 1.152962113 0.412257604 1.104681694 1 10.26408694 -9.648712802 1.499821862 1.000611916 1.238636341 0.007354378 0.325383442 0.984109649 3.997237826 0.230209698 0.052628249 2.25E-10 9.648712802 0.238024425 NCIVLIDSTPYR ddPTM_HeLa_Curcumin_4h_R1 2 NCIVLIDSTPYR 12 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 0 ; ; 176.95 4.26E-08 6309200 2999 2180.39 2582.4 2153.08 2560 3090.5 2536 1975.64 2683.58 2800.5 FALSE FALSE TRUE 2761.625985 2368.853196 2678.106016 2144.171125 2529.473672 2449.495463 2607.153335 2578.003541 2389.197988 2897.817167 0.953002148 0.817461234 0.924180465 0.739926297 0.872889326 0.845289859 0.899695593 0.889636369 0.824481964 1 11.50075086 -7.420215164 3.65609067 0.980479347 0.855815231 0.035913191 0.069373467 0.12212702 2.883132504 0.008445814 0.009497711 3.80E-08 7.420215164 -0.124664116 ERPDLEAPAPGS(ph)PFR ddPTM_HeLa_Curcumin_4h_R1 2 ERPDLEAPAPGSPFR 15 1 H0YBA8;Q9NQT8-2;Q9NQT8 H0YBA8 KIF13B Kinesin-like protein KIF13B 1 0 ERPDLEAPAPGS(1)PFR;ERPDLEAPAPGS(1)PFR ; 133.93 0.00028385 45430000 4209.7 3317.3 3706.5 3904.8 3834 3717.2 2471.9 684.2 4143.8 3198.7 TRUE FALSE FALSE 3876.497803 3604.03263 3843.866151 3888.642972 3788.282054 2946.210819 2541.254861 892.8094303 3689.235507 3309.854587 1.171198825 1.088879446 1.161339887 1.174868222 1.14454637 0.890133008 0.767784443 0.269742796 1.114621628 1 11.69255212 -4.323626795 1.309923957 1.099059545 4.59E-13 0.940607107 0.065502972 0.258269726 0.409629356 0.012320701 0.365808654 4.75E-05 4.323626795 -1.099059545 down NCSASTS(ph)QER ddPTM_HeLa_Curcumin_4h_R1 2 NCSASTSQER 10 0 H7BZV4;A0A0C4DG62;Q66PJ3-4;Q66PJ3-3;F8WEP2 H7BZV4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 0 NCSAS(0.001)T(0.012)S(0.986)QER;NCSAS(0.001)T(0.003)S(0.996)QER ; 134.18 0.0023281 59865000 17312.2 29110 18766.6 14134 14552.5 10978 7512.9 5965.5 11643.1 16108.9 TRUE FALSE FALSE 15941.9211 31626.13869 19462.1067 14075.51725 14378.97094 8701.039052 7723.691754 7784.353488 10365.88106 16668.68308 0.956399557 1.897338773 1.167585143 0.844428872 0.862633891 0.521999189 0.463365445 0.467004709 0.621877626 1 14.02485251 -5.460123254 1.610813914 1.068048302 0.455766626 0.435485202 0.307814435 0.285551763 1.435687255 0.045161803 0.134747687 3.47E-06 5.460123254 -0.612281676 NCSASTSQAS(ph)PSPCITER ddPTM_HeLa_Curcumin_4h_R1 1 NCSASTSQASPSPCITER 18 0 F5H7X4;Q66PJ3-7 F5H7X4 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 0 NCSASTS(0.002)QAS(0.929)PS(0.068)PCIT(0.001)ER 160.02 4.42E-13 0 637.68 587.95 527.97 675.01 702.03 749.81 392.09 309.61 754.41 578.16 TRUE FALSE FALSE 587.2069551 638.7697781 547.5370326 672.2169875 693.6587508 594.2909539 403.0909901 404.0086637 671.6531104 598.251017 0.981539418 1.067728696 0.915229589 1.123637016 1.159477763 0.9933806 0.673782373 0.675316301 1.122694473 1 9.224607134 -4.76980136 6.386659414 1.013153819 0.671808109 0.780896688 0.077130262 0.04443344 7.532399401 0.010044472 0.033576843 1.70E-05 4.76980136 -0.341345711 NCSETQYESK ddPTM_HeLa_Curcumin_4h_R1 3 NCSETQYESK 10 0 P61981 P61981 YWHAG "14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed" 0 0 ;; ;; 224.75 4.70E-35 27284500 4898.7 4108.97 4592.15 4025.31 4204.7 5039.1 4149.1 4611.58 4641.5 3831.4 FALSE FALSE TRUE 4510.962726 4464.131058 4762.339119 4008.654334 4154.561699 3993.933858 4265.512579 6017.629513 4132.339062 3964.540865 1.137827274 1.126014641 1.201233455 1.011127006 1.047930098 1.007413971 1.075915907 1.517862905 1.042324749 1 11.95293808 -4.261646955 7.896890118 1.071261093 1.521694148 0.822894668 0.062028129 0.033116779 24.01647819 0.010028951 0.079427982 5.47E-05 4.261646955 0.450433055 NCSS(ph)PEFSK ddPTM_HeLa_Curcumin_4h_R1 1 NCSSPEFSK 9 0 Q99829;Q5JX60;F2Z2V0;A6PVH9;E7ENH5;Q5JX45;Q5JX52;Q5JX44;Q5JX61;Q5JX59;Q5JX58;B0QZ18;Q5JX54;Q5JX56;Q5JX55;E7EV27;Q5JX57;Q5JX53 Q99829 CPNE1 Copine-1 1 0 NCS(0.275)S(0.694)PEFS(0.032)K 99.5 0.013423 27379000 8307.3 6272.5 6645.4 7238.8 7554.3 7995.4 6490 5924.5 7751.2 6315.8 TRUE FALSE FALSE 7649.768439 6814.66695 6891.68437 7208.847764 7464.219906 6337.063913 6672.091933 7730.852777 6900.912753 6535.27358 1.170535303 1.042751595 1.054536476 1.103067481 1.142143449 0.969670793 1.020935367 1.182942486 1.055948564 1 12.67403192 NDAPTPGTS(ph)TTPGLR ddPTM_HeLa_Curcumin_4h_R1 1 NDAPTPGTSTTPGLR 15 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 0 NDAPT(0.003)PGT(0.059)S(0.406)T(0.406)T(0.125)PGLR 132.15 0.00068238 127660000 4092.5 3679.3 3435 3875.6 3546.1 5225 4792 905.3 4573.4 2762.7 TRUE FALSE FALSE 3768.574307 3997.322297 3562.304122 3859.563794 3503.815074 4141.276102 4926.450623 1181.321803 4071.709462 2858.703619 1.318280874 1.39829896 1.246125726 1.350109808 1.225665735 1.448655283 1.723316328 0.413236893 1.424320253 1 11.48114534 -9.17732734 0.883688452 0.996643362 1.292111266 0 0.342651471 1.060600174 1.467861971 0.204065859 0.055634538 6.65E-10 9.17732734 0.295467904 NDAPTPGTSTT(ph)PGLR ddPTM_HeLa_Curcumin_4h_R1 3 NDAPTPGTSTTPGLR 15 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 0 NDAPT(0.001)PGT(0.01)S(0.035)T(0.216)T(0.738)PGLR;NDAPTPGT(0.001)S(0.007)T(0.044)T(0.947)PGLR;NDAPT(0.001)PGT(0.011)S(0.036)T(0.217)T(0.736)PGLR ;; 121.95 0.0034098 150141200 7738.4 6622.2 6254 7232.6 7926.5 9815.8 8584.3 1969.51 8345.8 6204.1 TRUE FALSE FALSE 7125.897474 7194.59346 6485.778742 7202.673418 7831.981664 7779.892433 8825.152355 2570.004532 7430.28662 6419.692013 1.110006128 1.120706951 1.010294377 1.121965571 1.219993365 1.211879389 1.374700272 0.400331438 1.157421042 1 12.64828837 -4.246810157 24.99994101 1.097392827 0.400330954 0.790684839 0.112702655 1023.335709 1748755.3 0.016948577 0.504089499 5.66E-05 4.246810157 -0.697061873 NDDDEEEAAR ddPTM_HeLa_Curcumin_4h_R1 1 NDDDEEEAAR 10 0 E7EX44;Q05682-3;Q05682-6;Q05682-2;C9JE79;F8WE61;C9JEK3;Q05682;Q05682-5;Q05682-4;E9PGZ1;C9J813 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 0 0 181.87 8.30E-16 2092000 487.91 721.74 580.01 475.72 598.86 594.67 328.91 415.01 590.32 540.55 FALSE FALSE TRUE 449.2914087 784.1239896 601.5056808 473.7515967 591.7189856 471.3287387 338.1383294 541.5446385 525.5633729 559.3340723 0.80326129 1.401888475 1.075396102 0.846992201 1.057899053 0.842660517 0.604537335 0.968195333 0.939623382 1 9.127566406 -5.008762154 24.13630825 0.959816065 0.77067449 0.183890458 0.180078923 376.7248162 1037747.594 0.026440804 0.073970342 9.80E-06 5.008762154 -0.189141575 NDDDEEEAARER ddPTM_HeLa_Curcumin_4h_R1 4 NDDDEEEAARER 12 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;C9JE79;F8WE61;C9JEK3;Q05682;Q05682-5;Q05682-4;E9PGZ1;C9J813 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 0 0 ;;; ;;; 155.88 0.00028398 86658200 18727.6 13001.4 13152 15693.3 12244.6 19167.5 14076.4 16276.2 21803 16482.9 FALSE FALSE TRUE 17245.2907 14125.18308 13639.42469 15628.36528 12098.59114 15191.94444 14471.3459 21238.73845 19411.26545 17055.67955 1.011117185 0.828180609 0.799699868 0.91631443 0.709358493 0.890726423 0.848476653 1.245259 1.138111524 1 14.05796462 -7.275568143 23.6158354 1.005249791 0.879947012 0.193444378 0.138497674 486.0039981 812340.2957 0.021376384 0.024517256 5.30E-08 7.275568143 -0.125302779 NDDIADGNPK ddPTM_HeLa_Curcumin_4h_R1 2 NDDIADGNPK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;E9PQ28;E9PIA2;E9PKG0;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 97.813 0.013152 4662400 6092.1 5856 5491.9 5450.8 6357.4 5113.9 4906.6 4662.7 5962.8 5141.4 FALSE FALSE TRUE 5609.903857 6362.166546 5695.434645 5428.246034 6281.592157 4053.219494 5044.265991 6084.335766 5308.695758 5320.063267 1.054480666 1.195881745 1.070557691 1.020334865 1.180736364 0.761874303 0.948159023 1.143658536 0.997863276 1 12.37722769 -5.285212895 24.98711906 1.051345343 0.950923354 0.193236649 0.108334734 1059.243733 1113315.067 0.015208644 0.034023554 5.19E-06 5.285212895 -0.100421988 NDEELNK(ac)LLGK ddPTM_HeLa_Curcumin_4h_R1 2 NDEELNKLLGK 11 1 A0A0U1RR32;A0A0U1RRH7;Q99878;Q96KK5;Q16777;Q6FI13;P20671;P0C0S8;Q9BTM1;Q9BTM1-2;H0YFX9 A0A0U1RR32 HIST1H2AJ;HIST1H2AH;HIST2H2AC;HIST2H2AA3;HIST1H2AD;HIST1H2AG;H2AFJ Histone H2A type 1-J;Histone H2A type 1-H;Histone H2A type 2-C;Histone H2A type 2-A;Histone H2A type 1-D;Histone H2A type 1;Histone H2A.J;Histone H2A 0 1 ; NDEELNK(1)LLGK;NDEELNK(1)LLGK 177.57 1.56E-11 6784810 902.99 1108.38 864.56 809.45 1298.03 2195.9 1875.76 1788.36 2427.02 1075.66 FALSE TRUE FALSE 831.5173887 1204.183428 896.6013541 806.1007104 1282.55184 1740.445587 1928.388777 2333.622731 2160.781978 1113.039105 0.747069339 1.0818878 0.805543444 0.724233953 1.152297196 1.563687726 1.7325436 2.096622411 1.941335186 1 10.12028857 -5.06324367 1.375168446 0.876855996 2.022822712 0.449417802 0.359034485 0.10446738 0.345377557 0.021168508 0.108933298 8.64E-06 5.06324367 1.145966716 NDEELNKLLGK ddPTM_HeLa_Curcumin_4h_R1 3 NDEELNKLLGK 11 1 A0A0U1RR32;A0A0U1RRH7;Q99878;Q96KK5;Q16777;Q6FI13;P20671;P0C0S8;Q9BTM1;Q9BTM1-2;H0YFX9 A0A0U1RR32 HIST1H2AJ;HIST1H2AH;HIST2H2AC;HIST2H2AA3;HIST1H2AD;HIST1H2AG;H2AFJ Histone H2A type 1-J;Histone H2A type 1-H;Histone H2A type 2-C;Histone H2A type 2-A;Histone H2A type 1-D;Histone H2A type 1;Histone H2A.J;Histone H2A 0 0 ;; ;; 106.16 0.0052472 148869000 18406.2 13494.7 13580.2 15533.7 10769.77 20580.4 15548.6 13817.2 21089.5 18008 FALSE FALSE TRUE 16949.32985 14661.12174 14083.49416 15469.42567 10641.34753 16311.79305 15984.85187 18030.00067 18776.03461 18633.77666 0.909602501 0.786803556 0.755804602 0.830181983 0.571078409 0.87538846 0.857842839 0.967597766 1.007634413 1 14.18563249 -7.623507426 1.424479523 0.972241082 0.80068518 0.376759071 0.098637593 0.294043531 1.22012518 0.02111104 0.021481602 2.38E-08 7.623507426 -0.171555902 NDEELNKLLGR ddPTM_HeLa_Curcumin_4h_R1 1 NDEELNKLLGR 11 1 Q93077;Q7L7L0;P04908 Q93077 HIST1H2AC;HIST3H2A;HIST1H2AB Histone H2A type 1-C;Histone H2A type 3;Histone H2A type 1-B/E 0 0 96.334 0.011493 32272000 3512.3 2543.9 2464.5 3568.9 2259.8 3674.1 2776.2 2674.5 4499.8 3667.6 FALSE FALSE TRUE 3234.297749 2763.783381 2555.836538 3554.132837 2232.853361 2912.050244 2854.0927 3489.942738 4006.183198 3795.048827 0.852241406 0.728260296 0.673466049 0.936518343 0.588359587 0.767328795 0.752056912 0.919604173 1.055634165 1 11.88990273 -8.16646268 0.788578626 0.981836419 0.76234856 0.479434432 0.102762009 0.358971514 0.483043721 0.034644746 0.022477331 6.82E-09 8.16646268 -0.219487859 NDFEIVLPENAEKELEER ddPTM_HeLa_Curcumin_4h_R1 1 NDFEIVLPENAEKELEER 18 1 Q99459 Q99459 CDC5L Cell division cycle 5-like protein 0 0 121.26 0.00034449 0 902.91 852.55 767.09 792.34 872.7 925.41 741.08 764.87 950.13 826.9 FALSE FALSE TRUE 831.4437208 926.2406231 795.5190302 789.061507 862.2936225 733.4695345 761.8727103 998.075342 845.9031161 855.6347135 0.97172743 1.082518753 0.929741416 0.92219436 1.00778242 0.857222741 0.890418187 1.166473644 0.988626458 1 9.740851204 NDFTEEEEAQVR ddPTM_HeLa_Curcumin_4h_R1 2 NDFTEEEEAQVR 12 0 E5RJR5;P63208 E5RJR5 SKP1 S-phase kinase-associated protein 1 0 0 ; ; 174.42 4.60E-07 4338600 1305.87 1084.4 1358.24 1429.52 1220.61 1420.42 1375.5 1056.84 1164.19 1019.35 FALSE FALSE TRUE 1202.509012 1178.130704 1408.577569 1423.605025 1206.055023 1125.808881 1414.092828 1379.065651 1036.48127 1054.772337 1.140064988 1.1169526 1.335432795 1.349679903 1.143426862 1.06734775 1.340661656 1.307453375 0.982658754 1 10.04271592 -7.951503074 0.535074894 1.005074473 1.253035484 0.522566417 0.094215392 0.517376567 0.350569886 0.051211613 0.033419426 1.12E-08 7.951503074 0.247961011 NDHLTSTTSS(ph)PGVIVPESSENK ddPTM_HeLa_Curcumin_4h_R1 1 NDHLTSTTSSPGVIVPESSENK 22 0 H7C608;E2QRF9;O75496 H7C608 GMNN Geminin 1 0 NDHLT(0.001)S(0.001)T(0.002)T(0.004)S(0.141)S(0.549)PGVIVPES(0.127)S(0.176)ENK 71.794 0.0013517 0 1378.6 1471.9 1294.9 1090.7 2377.5 3960.9 1959.2 1126.1 1703 1017.6 TRUE FALSE FALSE 1269.482355 1599.124477 1342.890133 1086.186972 2349.149865 3139.364691 2014.169879 1469.442706 1516.185161 1052.961524 1.205630335 1.518692222 1.275345872 1.031554285 2.230993072 2.981461923 1.912861802 1.395533144 1.439924561 1 10.04023701 -5.759474555 24.99869123 1.14525333 2.175491133 0.529340903 0.4013554 26.7443393 340262.4603 0.058512391 0.112496072 1.74E-06 5.759474555 1.030237803 NDHQEDFWK ddPTM_HeLa_Curcumin_4h_R1 2 NDHQEDFWK 9 0 A6NKB8;Q9H4A4 A6NKB8 RNPEP Aminopeptidase B 0 0 ; ; 106.62 0.0081755 16712300 11481.4 9448.4 9723.6 10146.3 10467.2 12025.6 9974.7 8668.6 11046.8 10464.9 FALSE FALSE TRUE 10572.63507 10265.07759 10083.96517 10104.3173 10342.38548 9531.355004 10254.56324 11311.61623 9834.993678 10828.5545 0.976366243 0.947963793 0.931238345 0.933117832 0.955103055 0.880205664 0.946992809 1.044609993 0.908246219 1 13.40255305 -7.538424468 1.441903591 0.992428285 0.944387964 0 0.046759534 0.403649921 1.683180943 0.007860344 0.00831046 2.89E-08 7.538424468 -0.048040321 NDIASHPPVEGSYAPR ddPTM_HeLa_Curcumin_4h_R1 1 NDIASHPPVEGSYAPR 16 0 Q7KZF4;H7C597 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 0 78.932 0.0083489 3225400 1655 1575.1 1397.8 1612.4 1530 1845.6 1346.4 1261.6 1890.8 1466.1 FALSE FALSE TRUE 1524.005004 1711.244625 1449.603698 1605.728316 1511.755749 1462.801756 1384.17636 1646.256032 1683.383971 1517.046866 1.004586633 1.128010389 0.955543121 1.058456632 0.996512226 0.964242957 0.912415029 1.085171506 1.10964533 1 10.56704994 -5.522674715 24.99932912 1.012942243 0.979888219 0.029869844 0.066391022 15.91417844 1949789.264 0.007952739 0.016046607 3.00E-06 5.522674715 -0.033054024 NDIMLL ddPTM_HeLa_Curcumin_4h_R1 1 NDIMLL 6 0 M0R2F7 M0R2F7 KLK15 0 0 65.263 0.016986 329800 1088.4 1078.4 822.3 1673.2 1113.6 0 120.45 241.98 1150.1 985.63 FALSE FALSE TRUE 1002.251992 1171.612091 852.7751614 1666.276742 1100.321047 0 123.8295028 315.7585881 1023.936907 1019.880569 0.982715057 1.148773814 0.836151984 1.633795948 1.078872449 0 0.12141569 0.309603494 1.003977268 1 9.994184503 -5.265638126 24.98366875 1.046161077 0.141447302 0.8053067 0.213924958 111.7508172 664949.3651 0.030342611 0.070186613 5.42E-06 5.265638126 -0.904713776 NDK(ac)SEEEQSSSSVK ddPTM_HeLa_Curcumin_4h_R1 2 NDKSEEEQSSSSVK 14 1 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 0 1 ; NDK(1)SEEEQSSSSVK;NDK(1)SEEEQSSSSVK 397.21 0 10365800 1566.36 3154.6 1858.4 1229.8 3708.9 4700.8 3453.2 2813.8 3280.8 1508.8 FALSE TRUE FALSE 1442.380953 3427.269567 1927.273939 1224.711413 3664.67379 3725.801091 3550.087498 3671.714667 2920.904448 1561.230688 0.923874328 2.195235845 1.234458145 0.784452562 2.347298076 2.386451356 2.273903227 2.351807901 1.87089869 1 10.60846801 -5.699037422 0.554587852 0.968238313 2.645768541 0.306407008 0.530178278 0.633312325 0.305544061 0.103822937 0.522727384 2.00E-06 5.699037422 1.677530228 NDKS(ph)EEEQSSSSVK ddPTM_HeLa_Curcumin_4h_R1 4 NDKSEEEQSSSSVK 14 1 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 0 NDKS(1)EEEQSSSSVK;NDKS(0.932)EEEQS(0.065)S(0.003)SSVK;NDKS(0.933)EEEQS(0.045)S(0.016)S(0.004)S(0.002)VK;NDKS(1)EEEQSSSSVK ;;; 229.02 2.00E-19 2329107000 8277.4 8233.14 8540.5 8138.58 9687.71 8834.03 8212.65 6543.59 6874.54 6641.59 TRUE FALSE FALSE 7622.235056 8944.775935 8857.018443 8104.904712 9572.190386 7001.752598 8443.074856 8538.700468 6120.420161 6872.384758 1.10911064 1.301553427 1.288783844 1.179343852 1.392848439 1.018824301 1.228550955 1.242465428 0.890581709 1 12.74659509 -7.651720642 1.758640392 1.035955772 1.232370522 0.509802733 0.104588602 0.205068047 1.310831826 0.018703925 0.019022122 2.23E-08 7.651720642 0.19641475 NDKS(ph)EEEQSSSSVKK ddPTM_HeLa_Curcumin_4h_R1 1 NDKSEEEQSSSSVKK 15 2 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 0 NDKS(1)EEEQSSSSVKK 102.5 0.0022405 40042000 5181.9 5241.7 5773.8 4611.2 5818.3 6403.8 5215.8 4623.7 4560 4740.4 TRUE FALSE FALSE 4771.747147 5694.769191 5987.782107 4592.120076 5748.920573 5075.579694 5362.14131 6033.444845 4059.779409 4905.128547 0.972807767 1.160982661 1.220718693 0.936187509 1.172022408 1.034749578 1.093170395 1.230027875 0.827660146 1 12.26007523 -7.270148615 24.78377527 0.98715922 1.115400998 0.407904678 0.097181245 444.1209394 1263827.282 0.013375443 0.015422049 5.37E-08 7.270148615 0.128241778 NDKSEEEQSSS(ph)SVK ddPTM_HeLa_Curcumin_4h_R1 1 NDKSEEEQSSSSVK 14 1 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 0 NDKSEEEQS(0.08)S(0.08)S(0.827)S(0.013)VK 106.31 0.0015442 5353600 1707 2123.5 2378.6 2307.9 2519.2 2653.9 2500.1 1702.6 2100.5 1910.3 TRUE FALSE FALSE 1571.889149 2307.045878 2466.753008 2298.350521 2489.160185 2103.451224 2570.246077 2221.714902 1870.080405 1976.682783 0.795215683 1.167130051 1.24792558 1.162731087 1.259261328 1.06413191 1.300282524 1.123961276 0.946070063 1 10.94886565 -7.19270464 7.035145374 0.90346123 1.193796474 0.711490546 0.080355268 0.110379517 9.767012733 0.015512977 0.019007175 6.42E-08 7.19270464 0.290335245 NDKSEEEQSSSSVK ddPTM_HeLa_Curcumin_4h_R1 2 NDKSEEEQSSSSVK 14 1 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 0 0 ; ; 210.07 1.28E-19 17392800 7884.6 8788.5 8221.7 6681.2 7677.4 9199.5 7535.9 5991.6 6378.7 7695.8 FALSE FALSE TRUE 7260.52559 9548.138779 8526.403435 6653.554965 7585.852019 7291.42 7747.337072 7818.411258 5678.972569 7963.228477 0.911756533 1.199028611 1.070721939 0.835534857 0.952610118 0.915636167 0.97288896 0.981814258 0.71314952 1 12.95913774 -6.271537285 24.91478368 0.986815856 0.934254904 0.03439164 0.121226721 1549.327865 3822687.611 0.014569513 0.022420176 5.35E-07 6.271537285 -0.052560952 NDKSEEEQSSSSVKKDETNVK ddPTM_HeLa_Curcumin_4h_R1 1 NDKSEEEQSSSSVKKDETNVK 21 3 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 0 0 36.481 0.016604 5346800 2287.9 1952.8 1914.5 1987.1 1181.1 2569.1 1772.2 1639.7 3264.4 2755.9 FALSE FALSE TRUE 2106.810301 2121.59133 1985.453054 1978.877907 1167.016154 2036.2397 1821.923162 2139.636982 2906.303487 2851.66732 0.738799469 0.743982763 0.696242875 0.693937155 0.409239937 0.714052332 0.638897514 0.750310868 1.019159376 1 11.47758997 -8.655252796 0.421278019 1.046921184 0.632713914 0.701634346 0.089752041 0.626910778 0.207966069 0.112229775 0.033402813 2.21E-09 8.655252796 -0.41420727 NDLAVVDVR ddPTM_HeLa_Curcumin_4h_R1 1 NDLAVVDVR 9 0 P19338 P19338 NCL Nucleolin 0 0 115.78 0.0017347 16304000 4279.1 3923.3 4202.4 4361.8 4454.7 5507.2 4502.7 4600.6 4666 4415.7 FALSE FALSE TRUE 3940.40472 4262.41257 4358.144641 4343.752027 4401.580612 4364.944641 4629.033644 6003.301761 4154.151474 4569.145246 0.862394279 0.932868697 0.953820552 0.950670594 0.963326919 0.955308795 1.013107134 1.313878513 0.909174747 1 12.15770859 -4.121070287 1.829637659 0.938226156 1.542813646 0.913668188 0.0342874 0.384228017 0.959354244 0.007257843 0.446506107 7.57E-05 4.121070287 0.60458749 NDLQDTEIS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 NDLQDTEISPR 11 0 Q9NS91 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 0 NDLQDTEIS(1)PR;NDLQDTEIS(1)PR;NDLQDTEIS(1)PR;NDLQDTEIS(1)PR ;;; 143.46 0.0011233 148543500 12293.7 13252.6 13555.5 11676.8 14491.8 13391.8 12077.4 8462.52 10750.9 11545.9 TRUE FALSE FALSE 11320.64067 14398.09569 14057.87875 11628.4845 14318.99475 10614.18972 12416.25934 11042.70339 9571.553167 11947.11917 0.94756238 1.205152095 1.176675193 0.973329581 1.198531173 0.888430891 1.039268058 0.924298422 0.801159931 1 13.54437516 -3.135069031 14.1190614 1.011790075 1.02681796 0 0.131599391 0 0 0.015073679 0 0.000732708 3.135069031 0.015027885 NDQEPPPEALDFS(ph)DDEKEK ddPTM_HeLa_Curcumin_4h_R1 2 NDQEPPPEALDFSDDEKEK 19 1 Q96HR8-2;Q96HR8 Q96HR8-2 NAF1 H/ACA ribonucleoprotein complex non-core subunit NAF1 1 0 NDQEPPPEALDFS(1)DDEKEK;NDQEPPPEALDFS(1)DDEKEK ; 131.32 7.01E-05 387650000 12727.5 12523.3 13989.8 12232.4 15822.6 14026.9 12970.2 12191.8 10061.7 10260.7 TRUE FALSE FALSE 11720.10495 13605.75825 14508.27429 12181.78557 15633.92583 11117.56282 13334.1089 15909.0237 8957.956683 10617.25856 1.103872989 1.281475644 1.366480265 1.147356966 1.472501187 1.047121793 1.255890005 1.498411629 0.843716542 1 13.37412368 -7.428953933 1.919464194 1.037916081 1.290461985 0.492505455 0.143024269 0.213550814 1.521047773 0.023438449 0.026113857 3.72E-08 7.428953933 0.252545904 NDQEPPPEALDFS(ph)DDEKEKEAK ddPTM_HeLa_Curcumin_4h_R1 4 NDQEPPPEALDFSDDEKEKEAK 22 2 Q96HR8-2;Q96HR8 Q96HR8-2 NAF1 H/ACA ribonucleoprotein complex non-core subunit NAF1 1 0 NDQEPPPEALDFS(1)DDEKEKEAK;NDQEPPPEALDFS(1)DDEKEKEAK;NDQEPPPEALDFS(1)DDEKEKEAK;NDQEPPPEALDFS(1)DDEKEKEAK ;;; 69.398 0.0018492 147896000 10745.2 9737.3 10083 10475.4 10000.6 11748.1 9702 8776.6 11501.4 10802.4 TRUE FALSE FALSE 9894.706082 10578.94882 10456.68485 10432.05557 9881.349377 9311.411632 9974.212008 11452.54494 10239.7252 11177.7826 0.885211892 0.946426425 0.935488301 0.933284887 0.884016959 0.833028515 0.892324745 1.024581113 0.9160784 1 13.4483464 -9.421626943 1.010056853 1.002970056 0.911709686 0 0.054324564 0.570476492 0.984960547 0.039360772 0.008701972 3.79E-10 9.421626943 -0.091260369 NDS(ph)GEENVPLDLTR ddPTM_HeLa_Curcumin_4h_R1 1 NDSGEENVPLDLTR 14 0 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 0 NDS(0.998)GEENVPLDLT(0.002)R 113.81 0.0023931 41654000 2427.6 2311.9 2486 2438.7 2956.2 2328.7 1847.9 1040.7 2274.5 2443 TRUE FALSE FALSE 2235.452898 2511.730334 2578.133347 2428.609306 2920.949246 1845.70137 1899.747101 1358.004639 2024.993041 2527.894068 0.88431431 0.99360585 1.019873965 0.960724318 1.155487203 0.730133985 0.75151373 0.53720789 0.801059295 1 11.30372029 -5.084742597 6.126165168 0.966886049 0.666393418 0.661755916 0.099363139 0.093481804 5.437748963 0.012481008 0.032574584 8.23E-06 5.084742597 -0.30049263 NDS(ph)GEENVPLDLTREPSDNLR ddPTM_HeLa_Curcumin_4h_R1 1 NDSGEENVPLDLTREPSDNLR 21 1 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 0 NDS(0.982)GEENVPLDLT(0.008)REPS(0.01)DNLR 55.789 0.0075448 23424000 731.38 500.78 649.28 689.17 650.49 890.61 595.54 323.7 870.37 725.64 TRUE FALSE FALSE 673.4905013 544.0651918 673.342888 686.3183971 642.7333316 705.8874468 612.2492496 422.3946399 774.8925886 750.855936 0.896963677 0.724593315 0.896767084 0.914048041 0.856000866 0.940110363 0.815401757 0.562550843 1.032012336 1 9.552392319 -1.289588544 0.161468251 1.003726033 1.92E-45 0.47386646 0.094550054 43.7299407 0.484009956 0.17120986 10.32234531 0.051334751 1.289588544 -1.003726033 QEPLEEDSPS(ph)SSSAGLDK ddPTM_HeLa_Curcumin_4h_R1 1 QEPLEEDSPSSSSAGLDK 18 0 P15408;P15408-3;P15408-2;C9JCN8 P15408 FOSL2 Fos-related antigen 2 1 0 QEPLEEDS(0.238)PS(0.514)S(0.238)S(0.01)SAGLDK 230.06 1.21E-23 124960000 1268.7 1369.1 1009.2 1063.6 1289.7 1431.4 1245.7 2128 1244.2 904.28 TRUE FALSE FALSE 1168.281056 1487.438903 1046.60184 1059.199105 1274.32117 1134.511505 1280.650989 2776.817404 1107.714373 935.7036627 1.248558815 1.589647409 1.118518481 1.13198136 1.361885414 1.212468808 1.368650183 2.96762481 1.183830327 1 9.86990789 -4.250205925 3.343498772 1.178480469 3.230475628 0.91503239 0.157200222 0.074725503 1.336635199 0.025284533 0.397197191 5.62E-05 4.250205925 2.051995159 up NDS(ph)LSSLDFDDDDVDLSR ddPTM_HeLa_Curcumin_4h_R1 1 NDSLSSLDFDDDDVDLSR 18 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 NDS(0.985)LS(0.013)S(0.002)LDFDDDDVDLSR 135.91 8.96E-06 0 1125 1118.8 914.29 1112.7 1264.8 1533.7 1200.8 1411.7 1229.8 1121 TRUE FALSE FALSE 1035.955063 1215.504087 948.1743917 1108.095942 1249.718086 1215.593332 1234.491216 1842.120831 1094.894017 1159.954667 0.893099612 1.047889303 0.817423662 0.955292456 1.077385282 1.047966241 1.064258157 1.588097263 0.943911041 1 10.17985271 -1.392194632 0.958543231 0.952594571 200 0.865571 0.07254823 136.8626078 0.512664309 0.011374872 59359.53426 0.040532685 1.392194632 199.0474054 NDS(ph)PTQIPVSSDVCR ddPTM_HeLa_Curcumin_4h_R1 1 NDSPTQIPVSSDVCR 15 0 Q8TC07-2;Q8TC07-3;Q8TC07 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 0 NDS(0.805)PT(0.195)QIPVSSDVCR 169.6 0.00017878 37289000 1879.6 1682.1 1598.6 1800.3 1373.8 1673.4 1108 979.33 1975.2 1772 TRUE FALSE FALSE 1730.827677 1827.493229 1657.845522 1792.850836 1357.418332 1326.317977 1139.087498 1277.923209 1758.525502 1833.576868 0.94396243 0.996682092 0.90415927 0.977788751 0.740311659 0.723350081 0.62123793 0.696956441 0.959068328 1 10.84044503 -5.662828418 2.558394815 0.970768926 0.675465687 0.924011024 0.037739023 0.051227129 0.678849453 0.005728747 0.012586236 2.17E-06 5.662828418 -0.295303239 ASLS(ph)LIEK ddPTM_HeLa_Curcumin_4h_R1 1 ASLSLIEK 8 0 P52292 P52292 KPNA2 Importin subunit alpha-1 1 0 AS(0.003)LS(0.997)LIEK 103.26 0.013266 37535000 1307.3 1152.1 1306.8 1165.9 1430.1 2518.2 2703.6 12538 1690 1402 TRUE FALSE FALSE 1203.825826 1251.68239 1355.231158 1161.075815 1413.046992 1995.896934 2779.45574 16360.77848 1504.611228 1450.719396 0.829813008 0.862801169 0.934178699 0.800344862 0.974031915 1.375798063 1.915915475 11.27770024 1.03714835 1 10.50255278 -4.25004432 3.474411623 0.945226393 12.68825494 0.99722149 0.162115533 0.013686958 0.276827523 0.028351813 0.427068218 5.62E-05 4.25004432 11.74302855 up GPPDFS(ph)S(ph)DEEREPT(ph)PVLGSGAAAAGR ddPTM_HeLa_Curcumin_4h_R1 1 GPPDFSSDEEREPTPVLGSGAAAAGR 26 1 G5E972;P42167;P42167-3;P42167-2;P42166 G5E972;P42166 TMPO "Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin" 3 0 GPPDFS(0.999)S(1)DEEREPT(0.941)PVLGS(0.06)GAAAAGR 59.07 0.0038852 16480000 4664.3 4103.2 4211.9 5011.8 3754.9 4654.2 3018.8 704.53 5651.8 4080.8 TRUE FALSE FALSE 4295.115733 4457.862324 4367.996719 4991.0625 3710.12527 3688.866456 3103.499403 919.3379537 5031.81168 4222.607496 1.017171437 1.055713165 1.034431148 1.181985895 0.878633705 0.873599182 0.734972267 0.21771807 1.191636136 1 12.04391844 -4.323448409 1.319552246 1.01911841 4.72E-18 0.883980084 0.091464187 0.234662187 0.3789424 0.010486441 0.309930305 4.75E-05 4.323448409 -1.01911841 down NDSGEENVPLDLTREPS(ph)DNLR ddPTM_HeLa_Curcumin_4h_R1 2 NDSGEENVPLDLTREPSDNLR 21 1 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 0 NDS(0.019)GEENVPLDLT(0.226)REPS(0.755)DNLR;NDSGEENVPLDLT(0.165)REPS(0.835)DNLR ; 78.917 0.00055175 87151000 2374.6 2019.5 2113 2290.5 1941.78 2733.7 1968.09 1423.28 2500.8 2502.74 TRUE FALSE FALSE 2186.647904 2194.056581 2191.309639 2281.022518 1918.625542 2166.699805 2023.309309 1857.23152 2226.468497 2589.710029 0.844360133 0.847220946 0.846160232 0.880802288 0.740865008 0.836657302 0.781287977 0.717158099 0.859736601 1 11.33857485 -13.52287875 0.09769822 1.650278675 0.661029305 0.434374996 0.05624551 36.18919846 0.264810019 4.8133521 0.338525229 3.00E-14 13.52287875 -0.98924937 NDSPT(ph)QIPVSSDVCR ddPTM_HeLa_Curcumin_4h_R1 4 NDSPTQIPVSSDVCR 15 0 Q8TC07-2;Q8TC07-3;Q8TC07 Q8TC07-2 TBC1D15 TBC1 domain family member 15 1 0 NDS(0.257)PT(0.743)QIPVSSDVCR;NDS(0.004)PT(0.996)QIPVSSDVCR;NDS(0.003)PT(0.997)QIPVSSDVCR;NDS(0.016)PT(0.984)QIPVSSDVCR ;;; 268.42 3.51E-50 301658200 14430.73 12131.13 11925.44 12753.24 11265.06 13824.94 10026.72 6746.88 14359.03 11986.53 TRUE FALSE FALSE 13288.52249 13179.69082 12367.4073 12700.47047 11130.73152 10957.4916 10308.04278 8803.972653 12783.88033 12403.06103 1.07139056 1.062615978 0.997125409 1.023978713 0.897418105 0.883450592 0.831088612 0.70982257 1.030703655 1 13.5984086 -4.800468101 0.719526125 1.037171132 0.653170337 0.921715828 0.03104793 0.355195388 0.196756378 0.006450826 0.094889286 1.58E-05 4.800468101 -0.384000795 NKAS(ph)PQSEFMPSK ddPTM_HeLa_Curcumin_4h_R1 1 NKASPQSEFMPSK 13 1 Q9NQW6;Q9NQW6-2;H7C1K5 Q9NQW6;H7C1K5 ANLN Actin-binding protein anillin 1 0 NKAS(0.975)PQS(0.012)EFMPS(0.014)K 146.27 0.0068513 11956000 2099 1649.8 1982.2 1750.8 1617.6 2506.2 2657 7182.8 2237 1762.3 TRUE FALSE FALSE 1932.861935 1792.401361 2055.662076 1743.555654 1598.311176 1986.385869 2731.548269 9372.802654 1991.606697 1823.539794 1.05995051 0.982924182 1.12729214 0.956137979 0.876488236 1.089302178 1.497937297 5.139894773 1.092165196 1 10.83252597 -4.250022858 3.240817145 1.023059431 5.781947047 0.996483011 0.072910777 0.014975518 0.242708241 0.011092258 0.180923056 5.62E-05 4.250022858 4.758887615 up GPS(ph)WDPFR ddPTM_HeLa_Curcumin_4h_R1 1 GPSWDPFR 8 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 0 GPS(1)WDPFR 140.11 0.0030349 263510000 2194.8 1453.7 2188.2 1968.9 2890.5 8865.7 9637.3 70783 0 980.14 TRUE FALSE FALSE 2021.079264 1579.35135 2269.296617 1960.753213 2856.032675 7026.853883 9907.696701 92364.41086 0 1014.199792 1.992782172 1.557238882 2.237524238 1.933300745 2.816045416 6.928471035 9.768979227 91.07121849 0 1 9.986126168 -4.249971868 3.558207531 2.063137471 102.6633733 0.995463758 1.786798498 0.015579899 0.340525308 0.288167965 4.231265463 5.62E-05 4.249971868 100.6002358 up NDY(ph)LPLY(ph)SS(ph)S(ph)T(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 NDYLPLYSSSTK 12 0 Q9UQR1 Q9UQR1 ZNF148 Zinc finger protein 148 5 0 NDY(0.999)LPLY(0.667)S(0.667)S(0.719)S(0.987)T(0.962)K 47.774 0.0091771 0 1126.1 794.18 1010.9 947.57 897.78 923.65 985.68 776.37 908.67 1030.7 TRUE FALSE FALSE 1036.967997 862.8253804 1048.364843 943.6492064 887.0745599 732.0745783 1013.335528 1013.081639 808.9911744 1066.516748 0.972294151 0.8090125 0.982980197 0.884795488 0.831749301 0.686416392 0.950135598 0.949897543 0.758535837 1 10.05869091 -7.323578809 0.898777588 0.99548458 0.861026992 0 0.111583626 0.460146196 0.748547335 0.019641917 0.022579897 4.75E-08 7.323578809 -0.134457588 NEACSSLELPNNEIRVVSMQVQTVTK ddPTM_HeLa_Curcumin_4h_R1 1 NEACSSLELPNNEIRVVSMQVQTVTK 26 1 Q58DX5 Q58DX5 NAALADL2 Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 0 0 42.325 0.013111 179740000 1603.1 1203.7 1432.2 1396.3 1495.7 1619.6 1129.4 1421 1722.5 1442 FALSE FALSE TRUE 1476.212943 1307.742464 1485.278592 1390.522481 1477.864754 1283.676703 1161.087924 1854.256359 1533.546059 1492.109393 0.989346325 0.876438732 0.995422051 0.931917249 0.990453355 0.860310048 0.778152011 1.242708053 1.027770529 1 10.54313759 -7.486178083 23.85728727 0.99529991 0.944580149 0.034746825 0.115866003 717.064608 466133.5151 0.018223033 0.020345214 3.26E-08 7.486178083 -0.050719761 NEDEEEEEEEKDEAEDLLGR ddPTM_HeLa_Curcumin_4h_R1 3 NEDEEEEEEEKDEAEDLLGR 20 1 Q9Y5B9 Q9Y5B9 SUPT16H FACT complex subunit SPT16 0 0 ;; ;; 204.71 7.78E-14 159557300 4137.3 3362.94 3764.6 4167.23 3504.05 3611 3733.5 3155.49 3846.6 3614 FALSE FALSE TRUE 3809.828339 3653.617549 3904.119388 4149.987106 3462.266492 2862.037896 3838.251962 4117.584375 3424.637604 3739.586231 1.01878339 0.977011178 1.04399769 1.109744996 0.925842133 0.765335446 1.02638413 1.101080205 0.91577982 1 11.86866294 NEEDAAELVALAQAVNAR ddPTM_HeLa_Curcumin_4h_R1 2 NEEDAAELVALAQAVNAR 18 0 P22314;P22314-2 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 0 ; ; 173.03 5.03E-05 4410700 1945.23 1366.83 1547.47 1921.14 1603.89 2606.44 1966.47 2156.49 2010.45 1814.32 FALSE FALSE TRUE 1791.262993 1484.972695 1604.820599 1913.190832 1584.764659 2065.834963 2021.643856 2813.993874 1789.908665 1877.367485 0.954135515 0.790986691 0.854824968 1.019081691 0.844141955 1.100389231 1.076850362 1.498904128 0.953414118 1 10.87449536 -3.682260995 1.129062425 0.951003039 2.74926089 0.809335279 0.082586232 1.727841033 0.712318245 0.012780306 5.072190619 0.000207845 3.682260995 1.798257851 NEEDEGHS(ph)NSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 NEEDEGHSNSSPR 13 0 Q14103-3;D6RAF8;Q14103;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 2 0 NEEDEGHS(0.999)NS(0.019)S(0.982)PR 106.6 0.0114 2016900 1804.1 1480.9 1620.6 1805.2 2336.6 1764.2 1308.6 1022.2 1055.6 1393.8 TRUE FALSE FALSE 1661.303581 1608.902397 1680.660862 1797.730561 2308.737571 1398.285033 1345.315794 1333.864074 939.803321 1442.234446 1.151895648 1.115562315 1.165317377 1.246489824 1.600806011 0.96952686 0.932799655 0.924859393 0.651630062 1 10.49408999 -5.026791862 24.99357797 1.133636115 0.934412689 0.138153495 0.219756629 842.1845064 785657.4132 0.02502611 0.064021608 9.40E-06 5.026791862 -0.199223426 NEEDEGHSNS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 3 NEEDEGHSNSSPR 13 0 Q14103-3;D6RAF8;Q14103;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 0 NEEDEGHSNS(0.5)S(0.5)PR;NEEDEGHS(0.002)NS(0.499)S(0.499)PR;NEEDEGHS(0.029)NS(0.486)S(0.486)PR ;; 169.15 9.05E-05 97073000 18991.1 28388.7 21892.4 15996.7 23665.8 19255.5 11574.4 10709.3 14574 17166.7 TRUE FALSE FALSE 17487.9344 30842.49273 22703.7516 15930.50989 23383.60079 15261.69225 11899.14651 13974.51627 12975.26866 17763.24155 0.9845013 1.736309932 1.278131108 0.896824482 1.316403919 0.859172703 0.669874723 0.786709804 0.730456129 1 14.11660726 -5.030128133 8.533601486 1.083287886 0.736738965 0.277207868 0.264892513 0.303760336 81.48332456 0.036369138 0.095589665 9.33E-06 5.030128133 -0.346548922 NEEDEGHSNSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 NEEDEGHSNSSPR 13 0 Q14103-3;D6RAF8;Q14103;D6RD83 Q14103-3 HNRNPD Heterogeneous nuclear ribonucleoprotein D0 1 0 NEEDEGHSNS(0.234)S(0.766)PR;NEEDEGHSNS(0.217)S(0.783)PR ; 163 9.38E-05 68790360 8235.07 13078.3 9981.94 6914.75 10038.62 8724.2 5139.23 4748.3 6205.15 7247.99 TRUE FALSE FALSE 7583.25552 14208.72998 10351.87948 6886.138597 9918.916013 6914.702578 5283.422962 6196.034812 5524.46057 7499.857113 1.011119999 1.894533424 1.380276893 0.918169305 1.322547332 0.921977909 0.704469816 0.826153714 0.736608776 1 12.87264739 -5.014489593 6.653164332 1.114747992 0.774909277 0.219182537 0.30577414 0.193512874 40.99782948 0.043249142 0.119643929 9.67E-06 5.014489593 -0.339838715 NEEPS(ph)EEEIDAPKPK ddPTM_HeLa_Curcumin_4h_R1 4 NEEPSEEEIDAPKPK 15 1 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 0 NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK;NEEPS(1)EEEIDAPKPK ;;; 103.4 0.0012793 5202230000 25582.3 20841.3 23439.7 25885.8 24592.2 27235.3 24056.2 18595.2 26942 21325 TRUE FALSE FALSE 23557.43396 22642.7291 24308.3959 25778.69142 24298.95408 21586.39177 24731.15223 24264.79088 23986.53001 22066.04216 1.067587644 1.026134589 1.101620115 1.168251707 1.101192225 0.978262962 1.120778799 1.099644 1.087033634 1 14.42954027 -8.633435087 0.461671212 0.991969378 1.090669338 0.003976905 0.05499402 1.20557897 0.488880822 0.053330537 0.016669129 2.33E-09 8.633435087 0.09869996 NEEPVRS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 NEEPVRSPER 10 1 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 0 NEEPVRS(1)PER 79.201 0.014326 35412000 1929.5 1814.3 1853.6 1802.1 2009.8 2120.1 1540.9 1187.7 1760.5 1789.5 TRUE FALSE FALSE 1776.778039 1971.120008 1922.296047 1794.643388 1985.834448 1680.367362 1584.133507 1549.824263 1567.377555 1851.684992 0.9595466 1.06450072 1.038133406 0.969194758 1.072447234 0.907480143 0.855509179 0.836980517 0.846460149 1 10.85462297 -5.021781979 4.585323932 0.995803814 0.851453118 0.490129759 0.060928612 0.081448889 4.314760211 0.005871131 0.016891152 9.51E-06 5.021781979 -0.144350695 NEESVLLFTQIK ddPTM_HeLa_Curcumin_4h_R1 1 NEESVLLFTQIK 12 0 Q03188 Q03188 CENPC Centromere protein C 0 0 93.821 0.016039 840780 260.38 536.89 353.51 228.02 337.34 511.09 524.96 593.23 263.38 0 FALSE FALSE TRUE 239.7706482 583.2963793 366.6113916 227.0765137 333.3174408 405.0841728 539.6889647 774.1030961 234.4878729 0 0 NEFS(ph)S(ph)FGS(ph)IS(ph)RVK ddPTM_HeLa_Curcumin_4h_R1 1 NEFSSFGSISRVK 13 1 P0CB38 P0CB38 PABPC4L Polyadenylate-binding protein 4-like 4 0 NEFS(1)S(1)FGS(1)IS(1)RVK 59.68 0.0092315 0 850.87 1079.3 1065.7 810.31 1113 1430.9 979.18 898.1 921.37 839.11 TRUE FALSE FALSE 783.5227417 1172.589883 1105.195779 806.9571519 1099.728202 1134.11521 1006.653155 1171.926556 820.2980162 868.26901 0.9023963 1.35049146 1.272872539 0.929386103 1.266575438 1.306179533 1.159379344 1.349727495 0.944751001 1 9.761998282 -7.271258182 24.97148836 0.953909359 1.224547259 0.549986833 0.117697226 380.1701159 966858.9359 0.020175262 0.023216666 5.35E-08 7.271258182 0.270637899 NEGSES(ph)APEGQAQQR ddPTM_HeLa_Curcumin_4h_R1 2 NEGSESAPEGQAQQR 15 0 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 0 NEGS(0.363)ES(0.637)APEGQAQQR;NEGS(0.169)ES(0.831)APEGQAQQR ; 216.72 2.79E-14 54520000 6510.6 5946.6 6444 6930.6 7245.2 5960.8 5097.1 2313.7 5178.6 6587.5 TRUE FALSE FALSE 5995.27914 6460.597606 6682.820309 6901.923014 7158.805722 4724.462888 5240.110908 3019.136479 4610.520536 6816.415135 0.879535507 0.947799903 0.980401014 1.012544406 1.050230301 0.693100815 0.768748793 0.442921451 0.676384939 1 12.73479749 -4.336564498 1.081171618 0.954433946 0.263291 0.599556708 0.117247693 0.522885941 0.525771955 0.012471566 0.39918585 4.61E-05 4.336564498 -0.691142946 NEGSESAPEGQAQQR ddPTM_HeLa_Curcumin_4h_R1 2 NEGSESAPEGQAQQR 15 0 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 0 ; ; 139.48 0.0016084 538560 159.07 0 0 0 79.792 161.45 0 0 0 0 FALSE FALSE TRUE 146.4794417 0 0 0 78.84053251 127.9634501 0 0 0 0 0 HS(ph)YPPALGSPGALAGAGVGAAGPLER ddPTM_HeLa_Curcumin_4h_R1 3 HSYPPALGSPGALAGAGVGAAGPLER 26 0 Q96IF1;H0YJL9 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 0 HS(0.991)Y(0.009)PPALGSPGALAGAGVGAAGPLER;HS(0.998)Y(0.002)PPALGSPGALAGAGVGAAGPLER;HS(0.972)Y(0.024)PPALGS(0.004)PGALAGAGVGAAGPLER ;; 114.68 9.62E-09 60171000 2542.51 2421.78 2480.78 2606.51 2655.3 3321.33 1956.56 777.22 2411.9 2144.08 TRUE FALSE FALSE 2341.267651 2631.107872 2572.719889 2595.724952 2623.637282 2632.448719 2011.455808 1014.1908 2147.320604 2218.58662 1.055296931 1.185938763 1.159621114 1.169990357 1.182571488 1.186543133 0.906638393 0.45713374 0.96787774 1 11.11542517 -4.323361756 2.943027978 1.077324294 0.39440228 0.8443661 0.084355016 0.111311363 1.461715641 0.013707932 0.165121524 4.75E-05 4.323361756 -0.682922014 down SSS(ph)LIQLTSQNSSPNQQR ddPTM_HeLa_Curcumin_4h_R1 4 SSSLIQLTSQNSSPNQQR 18 0 O95639;H7C419 O95639 CPSF4 Cleavage and polyadenylation specificity factor subunit 4 1 0 SSS(1)LIQLTSQNSSPNQQR;S(0.001)S(0.07)S(0.929)LIQLTSQNSSPNQQR;S(0.003)S(0.003)S(0.993)LIQLTSQNSSPNQQR;S(0.01)S(0.01)S(0.981)LIQLTSQNSSPNQQR ;;; 390.99 8.88E-249 53750300 3858.42 2742.26 3788.42 3753.88 3396.57 4298.76 4532.17 9816.4 3577.76 3062.62 TRUE FALSE FALSE 3553.021986 2979.288735 3928.822178 3738.347439 3356.068121 3407.148719 4659.330492 12809.37517 3185.288679 3169.045817 1.1211646 0.940121698 1.239749251 1.179644491 1.059015336 1.075133941 1.4702629 4.042029024 1.005125474 1 11.6298328 -4.249833806 3.060325335 1.074532219 4.555693208 0.990895062 0.084728878 0.025980397 0.352759627 0.012660738 0.221273516 5.63E-05 4.249833806 3.481160989 up NEIVANVGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 NEIVANVGKR 10 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 0 1 NEIVANVGK(1)R 82.831 0.0068127 0 2083.8 1977.1 1862.2 1826.7 1790.7 2900.9 1936.3 2157.6 2605.3 2156.6 FALSE TRUE FALSE 1918.865031 2147.991714 1931.21477 1819.141599 1769.347072 2299.22064 1990.627367 2815.442308 2319.505108 2231.541689 0.85988312 0.962559527 0.865417294 0.815194987 0.792881029 1.030328338 0.892041308 1.261657947 1.039418228 1 11.12382504 -4.258904715 24.84998701 0.916992411 1.26165808 0.606641367 0.083132492 111.2064767 1090202.693 0.011407403 0.103403942 5.51E-05 4.258904715 0.344665669 NELMYQLEQDHDLQAILQER ddPTM_HeLa_Curcumin_4h_R1 1 NELMYQLEQDHDLQAILQER 20 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 0 121.47 0.00016297 0 649.32 423.35 527.26 596.63 423.29 806.85 659.43 546.03 621.99 489.31 FALSE FALSE TRUE 597.9256368 459.9424876 546.8007194 594.1613031 418.2425432 639.5002149 677.931831 712.5120334 553.7592531 506.3134861 1.180939582 0.908414451 1.079964754 1.173504794 0.826054519 1.263051909 1.338956693 1.407254701 1.093708282 1 8.983887102 -5.027021485 12.29815064 1.064279829 1.355163112 0.623401536 0.107147189 0.746170292 340.063748 0.015746811 0.04091884 9.40E-06 5.027021485 0.290883283 NELQEPCDS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 NELQEPCDSPK 11 0 O94913 O94913 PCF11 Pre-mRNA cleavage complex 2 protein Pcf11 1 0 NELQEPCDS(1)PK 145.61 0.0009624 23087000 3717.5 3325.7 3747.3 3662.1 4279 3633.4 6111.2 2267.7 3769.9 3007.6 TRUE FALSE FALSE 3423.255952 3613.158689 3886.178234 3646.947201 4227.97572 2879.791883 6282.663825 2959.111291 3356.351402 3112.113876 1.099977729 1.160998226 1.248726232 1.171855319 1.35855431 0.925349135 2.018776971 0.950836444 1.078479624 1 11.60367914 -6.240530027 0.357106791 1.000676781 1.440484932 0.110335324 0.283357524 2.217822492 0.542276503 0.123529303 0.376225271 5.75E-07 6.240530027 0.439808151 NEMGIPQQTTS(ph)PENAGPQNTK ddPTM_HeLa_Curcumin_4h_R1 1 NEMGIPQQTTSPENAGPQNTK 21 0 Q15398-1;Q15398-3;Q15398 Q15398-1 DLGAP5 Disks large-associated protein 5 1 0 NEMGIPQQT(0.017)T(0.072)S(0.911)PENAGPQNTK 100.7 8.90E-05 8111600 3774.4 3294.8 3506.8 3839.1 3512.5 5301.7 4408.7 2555.2 4581 3826.9 TRUE FALSE FALSE 3475.652257 3579.587831 3636.765093 3823.214821 3470.615732 4202.067658 4532.396257 3334.268717 4078.475761 3959.88449 0.877715566 0.903962689 0.918401812 0.965486451 0.876443679 1.061159149 1.144577896 0.842011611 1.029948164 1 11.95124263 -5.251843283 24.92751786 0.934223366 1.028782388 0.141909762 0.084560641 765.8002049 1989292.912 0.011313273 0.028437097 5.60E-06 5.251843283 0.094559022 NENLAANFLLSQNFDDE ddPTM_HeLa_Curcumin_4h_R1 2 NENLAANFLLSQNFDDE 17 0 P54725-2;P54725-3;P54725;K7EQ16 P54725-2 RAD23A UV excision repair protein RAD23 homolog A 0 0 ; ; 136.01 0.0029923 19244400 8677.2 7272.3 8614.5 6400.9 9041.2 21060.4 14341.7 14903.8 8149.9 6651.3 FALSE FALSE TRUE 7990.390464 7900.885207 8933.760948 6374.414772 8933.389595 16692.23564 14744.0895 19447.90001 7255.87636 6882.43218 1.160983538 1.147978651 1.298052885 0.926186355 1.297998928 2.425339648 2.142278938 2.825730716 1.054260495 1 12.74870277 -5.299987314 3.612040057 1.092913843 2.453920658 0.920049524 0.181425458 0.041777919 1.143591257 0.024564747 0.061228779 5.01E-06 5.299987314 1.361006814 up NENTEGS(ph)PQEDGVELEGLK ddPTM_HeLa_Curcumin_4h_R1 1 NENTEGSPQEDGVELEGLK 19 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 NENT(0.008)EGS(0.992)PQEDGVELEGLK 132.6 0.0001697 19110000 8031.4 4950.4 8342.5 8979.7 8867.4 10023 8591.9 6428.7 7551.9 6160 TRUE FALSE FALSE 7395.706215 5378.290517 8651.680389 8942.544381 8761.662046 7944.116818 8832.96559 8388.781036 6723.475464 6374.059541 1.160281947 0.843777891 1.357326572 1.402959028 1.374581142 1.246319832 1.385767662 1.316081373 1.054818428 1 12.63799678 -6.729833927 24.9988463 1.060410212 1.348124459 0.768970917 0.087854461 83.01264217 65660.02022 0.014837637 0.020982495 1.86E-07 6.729833927 0.287714247 NENTEGS(ph)PQEDGVELEGLKQR ddPTM_HeLa_Curcumin_4h_R1 2 NENTEGSPQEDGVELEGLKQR 21 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 NENT(0.064)EGS(0.936)PQEDGVELEGLKQR;NENT(0.045)EGS(0.955)PQEDGVELEGLKQR ; 114.71 6.23E-06 24081000 2657.1 1535.44 2234.31 2832.22 1976.06 2972.9 2092.72 1803.41 3396.5 2706.1 TRUE FALSE FALSE 2446.787731 1668.156592 2317.115494 2820.501024 1952.496775 2356.287029 2151.436091 2353.261407 3023.912448 2800.136774 0.873810078 0.595741111 0.827500826 1.007272591 0.697286216 0.841489977 0.768332501 0.84040945 1.07991598 1 11.45128158 -8.193963745 1.129669949 0.975856263 0.803693103 0.403036841 0.108133244 0.351485161 0.929462759 0.02860493 0.021116369 6.40E-09 8.193963745 -0.17216316 NEPTTRS(ph)PVSSQQSLK ddPTM_HeLa_Curcumin_4h_R1 1 NEPTTRSPVSSQQSLK 16 1 Q8IWJ2 Q8IWJ2 GCC2 GRIP and coiled-coil domain-containing protein 2 1 0 NEPT(0.058)T(0.058)RS(0.883)PVS(0.002)SQQSLK 63.614 0.015289 4350300 1606.7 1047.2 1245.2 1137.2 1414.8 1923.4 1612.8 759.68 1419.5 1125.3 TRUE FALSE FALSE 1479.528 1137.715302 1291.348207 1132.494568 1397.929434 1524.465159 1658.050827 991.3029349 1263.784401 1164.404091 1.270631056 0.977079444 1.109020672 0.972595834 1.200553523 1.309223465 1.423947957 0.851339275 1.085348644 1 10.1853761 -9.630669399 1.447997571 0.999942105 1.163134357 0.027658086 0.167174466 0.744379338 2.802422056 0.116741794 0.026562968 2.34E-10 9.630669399 0.163192252 NEQMMEQK ddPTM_HeLa_Curcumin_4h_R1 1 NEQMMEQK 8 0 P32455 P32455 GBP1 Interferon-induced guanylate-binding protein 1 0 0 79.474 0.0091709 2295600 267.99 639.15 394.23 418.04 235.29 353.08 342.32 210.99 443.39 495.11 FALSE FALSE TRUE 246.7783087 694.395278 408.8405106 416.3102612 232.4843204 279.847228 351.9245779 275.3198797 394.7512263 512.3150356 0.481692497 1.35540679 0.798025594 0.812605979 0.453791718 0.546240513 0.68693002 0.537403474 0.770524382 1 9.000887423 -5.778064794 24.29118882 0.806708632 0.564733425 0.309062176 0.217672969 237.5666074 347105.5118 0.038658688 0.070229464 1.67E-06 5.778064794 -0.241975207 NESS(ph)PAPPDSDADKLK ddPTM_HeLa_Curcumin_4h_R1 1 NESSPAPPDSDADKLK 16 1 Q8ND04;Q8ND04-2;J3KTD7 Q8ND04 SMG8 Protein SMG8 1 0 NES(0.348)S(0.651)PAPPDSDADKLK 82.859 0.0046611 17281000 4996.9 4596.9 6032 5133 6571.9 5317.6 4770.5 4084 4788.7 4683.1 TRUE FALSE FALSE 4601.390092 4994.235553 6255.551226 5111.761006 6493.534385 4214.669818 4904.347391 5329.1928 4263.391591 4845.837376 0.949555203 1.030623846 1.290912332 1.054876714 1.340023175 0.86975057 1.012074284 1.099746522 0.879804925 1 12.24253027 -6.993572979 24.96955564 0.976910978 1.108350484 0.243111966 0.129168335 198.3262683 770510.3897 0.019718287 0.025879751 1.01E-07 6.993572979 0.131439507 NETSFLPAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 NETSFLPAKK 10 1 F8WAJ0;Q9H8H2-3;Q9H8H2-4;Q9H8H2-2;Q9H8H2 F8WAJ0 DDX31 Probable ATP-dependent RNA helicase DDX31 0 1 NETSFLPAK(1)K 141.88 4.91E-17 0 1226.1 1231.8 1245.8 1248.2 1188 1504.3 1153.7 762.72 1581.8 1329.8 FALSE TRUE FALSE 1129.052891 1338.271303 1291.970444 1243.035279 1173.833876 1192.291223 1186.069717 995.2698169 1408.280497 1376.010451 0.820526392 0.972573502 0.938924877 0.903361801 0.853070465 0.866484133 0.861962724 0.723301059 1.023451891 1 10.42627571 -13.52287875 0.281974469 2.031106993 0.853592912 0.475632613 0.062381683 38.70071993 0.522429565 22.56858515 0.031130081 3.00E-14 13.52287875 -1.177514081 NEVAQLK ddPTM_HeLa_Curcumin_4h_R1 1 NEVAQLK 7 0 K7ELQ4;P17544-4;P17544-2;P17544;P17544-3;P17544-1;Q02930-3;F5H629;Q02930-2;H0YFV2;P15336-4;Q02930-4;P15336-2;P15336-8;P15336-6;Q02930;B8ZZU6;P15336-5;P15336 K7ELQ4;B8ZZU6 ATF7;CREB5;ATF2 Cyclic AMP-dependent transcription factor ATF-7;Cyclic AMP-responsive element-binding protein 5;Cyclic AMP-dependent transcription factor ATF-2 0 0 101.64 0.019944 5681800 2971 1659.3 2093.4 1718.3 2284.6 2896.1 2057.8 1859.5 1967 2127.3 FALSE FALSE TRUE 2735.842215 1802.722498 2170.983246 1711.19013 2257.357637 2295.416214 2115.53633 2426.45299 1751.225021 2201.223517 1.242873427 0.818963856 0.986262062 0.777381359 1.025501327 1.042791065 0.961072928 1.102320129 0.795568922 1 11.10408993 -7.264107626 24.99505364 1.114690227 0.959072575 0 0.147224339 246.4613993 2308745.296 0.021219707 0.024847193 5.44E-08 7.264107626 -0.155617651 NEVNGTSEDIKSEGDTQS(ph)N ddPTM_HeLa_Curcumin_4h_R1 3 NEVNGTSEDIKSEGDTQSN 19 1 O95232 O95232 LUC7L3 Luc7-like protein 3 1 0 NEVNGTSEDIKS(0.018)EGDT(0.018)QS(0.964)N;NEVNGTSEDIKS(0.219)EGDT(0.043)QS(0.738)N;NEVNGTSEDIKS(0.007)EGDT(0.005)QS(0.988)N ;; 139.98 0.0015735 29552600 10538 9204.96 10560 8819.33 12677.2 12387.3 10224.6 9237.3 9048.17 7359.4 TRUE FALSE FALSE 9703.90618 10000.59573 10951.36289 8782.837949 12526.03267 9818.034346 10511.47476 12053.71025 8055.608388 7615.138602 1.274291472 1.313251964 1.438104211 1.153339211 1.64488571 1.289278483 1.380339257 1.58286157 1.057841335 1 12.89465458 -12.13582782 0.112096233 5.45E-13 1.653413707 0.599664488 0.125557191 31.33144534 0.358654301 7.934782369 0.776138385 7.31E-13 12.13582782 1.653413707 NEVQGRDDALER ddPTM_HeLa_Curcumin_4h_R1 2 NEVQGRDDALER 12 1 E7EPG1;Q13201 E7EPG1 MMRN1 Multimerin-1;Platelet glycoprotein Ia*;155 kDa platelet multimerin 0 0 ; ; 84.605 0.01749 9344400 1914.36 2810.1 1828.52 2174.34 2213.7 2530.8 2080.55 2137.9 2798.9 2692 FALSE FALSE TRUE 1762.836386 3052.992522 1896.28656 2165.343157 2187.303073 2005.883552 2138.924633 2789.735868 2491.867673 2785.5468 0.632851111 1.096011929 0.680759182 0.777349409 0.785232929 0.720104057 0.767865266 1.001503859 0.894570385 1 11.44374484 -9.639326595 1.466047995 0.999990833 0.780938467 0.101733316 0.13890024 0.450917253 1.741950078 0.095815342 0.021749918 2.29E-10 9.639326595 -0.219052367 NFDFEGSLS(ph)PVIAPK ddPTM_HeLa_Curcumin_4h_R1 2 NFDFEGSLSPVIAPK 15 0 H0Y564;Q9H1A4 H0Y564 ANAPC1 Anaphase-promoting complex subunit 1 1 0 NFDFEGS(0.109)LS(0.891)PVIAPK;NFDFEGS(0.11)LS(0.89)PVIAPK ; 182.91 4.00E-05 442050000 11344.1 8528 10440.5 9748.9 9582.7 11163.7 10608.9 14944.4 11433.7 9889.1 TRUE FALSE FALSE 10446.20251 9265.12232 10827.43411 9708.561635 9468.432561 8848.222779 10906.55718 19500.87876 10179.45172 10232.74549 1.020860191 0.905438558 1.058116233 0.948773879 0.92530715 0.864696849 1.065848573 1.905732805 0.99479184 1 13.32090566 -4.265026031 4.351198772 0.987120896 1.969862472 0.95884217 0.057967635 0.028488482 1.283045374 0.008293869 0.085751229 5.43E-05 4.265026031 0.982741576 NFEDS(ph)SPETLEAHK ddPTM_HeLa_Curcumin_4h_R1 1 NFEDSSPETLEAHK 14 0 F8WDV0;Q9UI26;Q9UI26-2 F8WDV0 IPO11 Importin-11 1 0 NFEDS(0.589)S(0.391)PET(0.02)LEAHK 84.653 0.0049088 0 3653.5 3075.2 3072.8 3643.8 3822.1 3122.4 2816.2 5527 3273.1 2762.8 TRUE FALSE FALSE 3364.32162 3341.006585 3186.680671 3628.722921 3776.523954 2474.779043 2895.214993 7212.156857 2914.049119 2858.807094 1.176827085 1.168671573 1.114688947 1.269313669 1.321013916 0.865668428 1.012735346 2.52278542 1.019323453 1 11.48119756 -4.259223913 24.95215588 1.102975318 2.522785924 0.915367183 0.129296558 40.370332 454647.4375 0.01877745 0.166271582 5.51E-05 4.259223913 1.419810606 NFEDSS(ph)PETLEAHK ddPTM_HeLa_Curcumin_4h_R1 1 NFEDSSPETLEAHK 14 0 F8WDV0;Q9UI26;Q9UI26-2 F8WDV0 IPO11 Importin-11 1 0 NFEDS(0.178)S(0.822)PETLEAHK 73.597 0.013088 4436400 4153.4 3868 3861.1 4034.6 3623.8 4092.3 3955.6 8212.2 3736.6 3928.1 TRUE FALSE FALSE 3824.654007 4202.332685 4004.195763 4017.905894 3580.588552 3243.51085 4066.58349 10716.06198 3326.704329 4064.601183 0.940966613 1.033885613 0.98513866 0.988511717 0.880920019 0.797989939 1.0004877 2.636436269 0.818457748 1 11.98889809 -4.261837213 6.383568262 0.960164044 2.672108892 0.976821494 0.078426236 0.01062205 2.469493628 0.009395562 0.078420646 5.47E-05 4.261837213 1.711944848 NFEDVAFDEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 NFEDVAFDEKK 11 1 P07237;H7BZ94;H0Y3Z3 P07237 P4HB Protein disulfide-isomerase 0 1 NFEDVAFDEK(1)K 84.605 0.011489 674280 327.62 433.44 452.6 180.7 520.65 719.05 503.12 384.69 568.59 295.94 FALSE TRUE FALSE 301.6885313 470.9046222 469.3737541 179.9523113 514.4415888 569.9109246 517.2361931 501.9802101 506.2170995 306.223893 0.985189393 1.537778838 1.532779659 0.587649479 1.679952481 1.861092285 1.689078498 1.639258796 1.653094717 1 8.258443043 -5.687480104 0.462118438 0.97935165 1.903513298 0.07442024 0.375292714 1.141156106 0.361179058 0.087185163 0.47179168 2.05E-06 5.687480104 0.924161648 NFEHLNSDFDR ddPTM_HeLa_Curcumin_4h_R1 2 NFEHLNSDFDR 11 0 P48163 P48163 ME1 NADP-dependent malic enzyme 0 0 ; ; 173.04 0.00017776 19817700 10169.1 9254.6 9651.6 7910.1 11456.9 17834.8 11984.3 10673.5 11115.7 9606.9 FALSE FALSE TRUE 9364.205005 10054.52639 10009.29679 7877.370102 11320.28395 14135.66144 12320.5472 13927.80102 9896.33552 9940.73906 0.942002898 1.011446566 1.006896643 0.792433043 1.138776894 1.421993008 1.239399518 1.401083051 0.995533175 1 13.2791374 -5.501244151 5.207638965 0.96632139 1.336665096 0.844097892 0.0761544 0.049098615 3.827575019 0.010191827 0.022283935 3.15E-06 5.501244151 0.370343706 S(ph)RTGS(ph)ESS(ph)QTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 3 0 S(0.727)RT(0.329)GS(0.94)ES(0.257)S(0.746)QTGTSTTSSR 88.504 0.0022683 17711000 2509 2325.4 2332.4 2539.8 2274.5 2910.3 1827.9 369.48 2440.8 2820.2 TRUE FALSE FALSE 2310.410003 2526.397214 2418.840796 2529.290981 2247.378073 2306.670974 1879.185954 482.1327511 2173.050347 2918.20174 0.791723879 0.865737683 0.828880595 0.86672931 0.7701243 0.790442601 0.643953408 0.165215703 0.744653914 1 11.51086391 -4.323057803 1.486215145 0.880244756 3.56E-28 0.869362382 0.076899405 0.282455947 0.614696981 0.013045996 0.351919434 4.75E-05 4.323057803 -0.880244756 down AAS(ph)PHQVTPQADEK ddPTM_HeLa_Curcumin_4h_R1 1 AASPHQVTPQADEK 14 0 Q96L73-2;Q96L73-3;Q96L73 Q96L73-2 NSD1 "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific" 1 0 AAS(1)PHQVTPQADEK 124.5 0.00066846 3760900 4840.6 3529.9 4418.1 4554.1 4717.1 4263.6 2824.9 804.54 4340.5 3542.6 TRUE FALSE FALSE 4457.461402 3835.008827 4581.838673 4535.256341 4660.851663 3379.281299 2904.159091 1049.840542 3864.358009 3665.705086 1.215990184 1.04618586 1.249920156 1.237212551 1.271474806 0.921863931 0.792251156 0.286395255 1.054192282 1 11.83987501 -4.323053609 1.426329118 1.129404105 0.016242397 0.871987232 0.101329207 0.317152109 0.62205404 0.017376769 0.484911858 4.75E-05 4.323053609 -1.113161708 down TSDPLASK(ac)TTTTK ddPTM_HeLa_Curcumin_4h_R1 2 TSDPLASKTTTTK 13 1 A0A3B3IRW6;Q2KHR3-2;Q2KHR3;H0YCQ7 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 0 1 ; TSDPLASK(1)TTTTK;TSDPLASK(1)TTTTK 205.31 1.10E-19 5079600 3464.7 2977.1 3209.3 3281.9 3015 3791.1 2338.6 940.82 3452.7 2469.5 FALSE TRUE FALSE 3190.465339 3234.427258 3328.239481 3268.320367 2979.048094 3004.783125 2404.214822 1227.671687 3073.947448 2555.314941 1.248560515 1.265764625 1.302477212 1.279028395 1.165824238 1.175895416 0.940868299 0.480438504 1.202962265 1 11.3192854 -4.30935058 2.137357822 1.162150303 0.336131256 0.85535965 0.090166822 0.23248167 1.273099099 0.017922568 0.351955918 4.91E-05 4.30935058 -0.826019047 down NFGEDMDDER ddPTM_HeLa_Curcumin_4h_R1 3 NFGEDMDDER 10 0 P11940;P11940-2;E7EQV3;A0A087WTT1;E7ERJ7;H0YAR2;Q9H361;H0YBN4 P11940 PABPC1;PABPC3 Polyadenylate-binding protein 1;Polyadenylate-binding protein;Polyadenylate-binding protein 3 0 0 ;; ;; 218.6 1.16E-09 113099000 10747.9 9768.9 10825.1 10240.3 12530.9 12869.6 11585.3 9754.1 9113.8 8557.3 FALSE FALSE TRUE 9897.192374 10613.28019 11226.28773 10197.92835 12381.4772 10200.29989 11910.35234 12728.08019 8114.038942 8854.665538 1.117737574 1.198608817 1.267838709 1.151701135 1.398299817 1.151968964 1.345093418 1.437443361 0.916357474 1 13.1122221 -1 0.092493516 0.803689254 2.478828743 0.750314025 0.079510668 48.0164981 0.320627418 0.752881759 10.25044595 0.1 1 1.675139489 NFGEDMDDERLK ddPTM_HeLa_Curcumin_4h_R1 1 NFGEDMDDERLK 12 1 P11940;P11940-2;E7EQV3;A0A087WTT1;E7ERJ7;H0YAR2;Q9H361;H0YBN4 P11940 PABPC1;PABPC3 Polyadenylate-binding protein 1;Polyadenylate-binding protein;Polyadenylate-binding protein 3 0 0 102.33 0.0068949 13608000 1748 1525.4 1403.5 1128.8 1431 1890.5 1601.2 1757.9 1394.9 1422.9 FALSE FALSE TRUE 1609.643956 1657.248779 1455.514945 1124.129325 1413.93626 1498.38899 1646.125363 2293.875618 1241.88296 1472.345669 1.093251394 1.125584035 0.988568768 0.763495522 0.960329011 1.017688319 1.11802914 1.557973556 0.843472417 1 10.5239007 -4.251699179 2.652948958 1.019579426 1.673873705 0.711714134 0.10875115 0.205310174 1.837066655 0.014602466 0.299024045 5.60E-05 4.251699179 0.654294279 NFGIGQDIQPK ddPTM_HeLa_Curcumin_4h_R1 2 NFGIGQDIQPK 11 0 P62424;Q5T8U3 P62424 RPL7A 60S ribosomal protein L7a 0 0 ; ; 201.75 2.60E-22 13022600 9772.2 8518.5 8511.6 9037.7 8139.9 10198.3 7418 7734.8 9817.5 9125.5 FALSE FALSE TRUE 8998.720058 9254.801182 8827.047384 9000.304392 8042.837009 8083.057621 7626.129115 10093.10491 8740.544812 9442.610446 0.952990713 0.980110451 0.934810075 0.953158498 0.851759908 0.856019389 0.807629327 1.068889262 0.925649201 1 13.20497004 -6.19975784 1.680487564 0.976833252 0.889169053 0.12357369 0.068973563 0.368976512 2.036482228 0.010246795 0.019035278 6.31E-07 6.19975784 -0.087664199 NFILDQTNVSAAAQR ddPTM_HeLa_Curcumin_4h_R1 2 NFILDQTNVSAAAQR 15 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PRZ7;A0A1W2PQD4;A0A1W2PQ74 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 0 ; ; 290.1 5.84E-112 4921000 2417.83 1989.08 2274.73 1855.71 2103.7 2555.5 1993.67 1492.09 2416 2000.44 FALSE FALSE TRUE 2226.456204 2161.007212 2359.033495 1848.031564 2078.614751 2025.460494 2049.607015 1947.021372 2150.970845 2069.955141 1.075606017 1.043987461 1.139654405 0.892788219 1.004183477 0.978504535 0.990169774 0.940610419 1.039138869 1 11.01538379 -6.251500281 24.99635675 1.044450486 0.966201509 0.531093368 0.045001802 565.0220614 1421003.931 0.007323227 0.012041702 5.60E-07 6.251500281 -0.078248978 T(ph)SDSDQQAYLVQR ddPTM_HeLa_Curcumin_4h_R1 3 TSDSDQQAYLVQR 13 0 Q96CV9-3;Q96CV9-2;Q96CV9 Q96CV9-3 OPTN Optineurin 1 0 T(0.999)S(0.001)DSDQQAYLVQR;T(0.986)S(0.014)DSDQQAYLVQR;T(0.877)S(0.116)DS(0.007)DQQAYLVQR ;; 244.23 1.28E-26 88482000 4151.8 3809.5 3600.5 3752.9 4157.3 5612.9 4969.7 9797.5 5219.9 4595 TRUE FALSE FALSE 3823.180649 4138.776205 3733.937697 3737.371494 4107.726913 4448.72127 5109.136407 12784.71265 4647.29003 4754.675908 0.80408859 0.87046442 0.785319077 0.786041271 0.863934155 0.935651842 1.074549876 2.688871523 0.97741468 1 12.21513129 -4.24978736 3.346384042 0.885538787 2.954243435 0.982462163 0.072125448 0.037520146 0.672390102 0.012779593 0.201266097 5.63E-05 4.24978736 2.068704648 up NFPNAIEHTLQWAR ddPTM_HeLa_Curcumin_4h_R1 1 NFPNAIEHTLQWAR 14 0 P22314;P22314-2 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 0 124.47 0.0011312 15998000 2701.3 1718 2255.2 1757.4 2045.4 4085.6 3039.4 2898.1 2334.3 1915.6 FALSE FALSE TRUE 2487.489255 1866.496265 2338.779696 1750.128344 2021.009941 3238.200506 3124.677384 3781.717349 2078.23313 1982.166957 1.254934275 0.941644324 1.179910545 0.882936898 1.019596222 1.633666878 1.576394648 1.90787024 1.048465228 1 10.95286277 -5.207814409 4.961077222 1.089568295 1.705702893 0.837354899 0.13236281 0.071881584 3.894185228 0.020783695 0.054020551 6.20E-06 5.207814409 0.616134598 NFRNPLAK ddPTM_HeLa_Curcumin_4h_R1 1 NFRNPLAK 8 1 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 0 98.997 0.0068636 5711000 2563.5 1610.6 2009.4 1648.5 1508.5 2791.3 1913.5 2774.3 2894 2391.3 FALSE FALSE TRUE 2360.59627 1749.813087 2083.870132 1641.678944 1490.512123 2212.352916 1967.18766 3620.171299 2576.53544 2474.397497 0.95400851 0.707167336 0.842172745 0.663466135 0.602373759 0.894097621 0.795016832 1.463051633 1.041277904 1 11.27286156 -4.255571701 24.73355017 0.889905233 1.463051923 0.601036081 0.147575651 360.4947223 1519512.546 0.023458861 0.280144298 5.55E-05 4.255571701 0.573146691 NFS(ph)CGSVEFDEADLESLR ddPTM_HeLa_Curcumin_4h_R1 1 NFSCGSVEFDEADLESLR 18 0 G5E9V3;E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;E9PDY7;A0A1W2PQ63 G5E9V3 PHLDB2 Pleckstrin homology-like domain family B member 2 1 0 NFS(1)CGSVEFDEADLESLR 172.55 6.62E-06 3098400 958.67 670.07 671.76 1080.1 862.86 1269.5 1180.7 677.78 976.11 1056.4 TRUE FALSE FALSE 882.7902579 727.987865 696.6560165 1075.630832 852.5709581 1006.19139 1213.827264 884.4320019 869.0331751 1093.109821 0.807595212 0.665978707 0.637315668 0.984009851 0.779949957 0.920485179 1.110434872 0.809097114 0.795009941 1 10.09422264 -3.956805972 16.8672288 0.88287914 0.41424778 0 0.144385194 20588215.65 203910572.1 0.021233644 307727139.4 0.000110457 3.956805972 -0.46863136 NFS(ph)DNQLQEGK ddPTM_HeLa_Curcumin_4h_R1 2 NFSDNQLQEGK 11 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 1 0 NFS(1)DNQLQEGK;NFS(1)DNQLQEGK ; 178.67 0.0001724 74921000 6242 4883.7 4825.3 5557.8 5022.6 7676.6 6133.5 21313.2 6059 5998.1 TRUE FALSE FALSE 5747.939113 5305.825267 5004.129863 5534.803296 4962.708775 6084.386627 6305.589503 27811.49657 5394.342859 6206.533529 0.926111023 0.854877403 0.806268079 0.891770466 0.799594291 0.980319626 1.015959951 4.481003194 0.869139405 1 12.599572 -4.261213863 6.106924262 0.93106148 4.571219842 0.995567054 0.071591681 0.006509644 1.217798598 0.011401555 0.097703311 5.48E-05 4.261213863 3.640158363 NFS(ph)IQVR ddPTM_HeLa_Curcumin_4h_R1 1 NFSIQVR 7 0 I3L4X8;H3BM21;P05106-2;P05106-3;P05106 I3L4X8 ITGB3 Integrin beta;Integrin beta-3 1 0 NFS(1)IQVR 85.265 0.013957 5768000 1141.5 584.55 737.66 888.92 1095.2 850.3 723.28 717.23 894.92 1017.8 TRUE FALSE FALSE 1051.14907 635.0758973 764.9983285 885.2418846 1082.140455 673.9381951 743.5732902 935.9101253 796.749515 1053.168474 0.998082544 0.603014535 0.726377923 0.840551067 1.027509351 0.639914896 0.706034512 0.888661357 0.756526173 1 10.04052053 -7.304003552 22.33958044 0.99909469 0.778329988 0.104748041 0.13956936 93.65166314 49152.2427 0.019856114 0.022706568 4.97E-08 7.304003552 -0.220764703 SKT(ph)PPPPPQTAQTK ddPTM_HeLa_Curcumin_4h_R1 2 SKTPPPPPQTAQTK 14 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 S(0.17)KT(0.83)PPPPPQTAQTK;S(0.242)KT(0.758)PPPPPQTAQTK ; 124.45 0.0011614 142878000 12224.6 9714.2 10420.8 10408.9 10105.9 10734 6667.2 2429.5 10396.2 9558.3 TRUE FALSE FALSE 11257.01001 10553.85216 10807.00402 10365.83073 9985.393743 8507.647403 6854.263688 3170.243366 9255.76287 9890.450214 1.138169625 1.067075 1.092670584 1.048064598 1.009599515 0.860188082 0.69301837 0.320535799 0.935828266 1 13.27182048 -4.322901672 0.997969711 1.069238907 1.30E-17 0.94324586 0.055587954 0.25475778 0.207737696 0.008218999 0.283962332 4.75E-05 4.322901672 -1.069238907 down NFSDNQLQEGK ddPTM_HeLa_Curcumin_4h_R1 2 NFSDNQLQEGK 11 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 0 ; ; 305.74 1.77E-135 52342000 9602.5 7725.8 8868.6 8687.8 8971.3 10225.9 8258.1 8381.3 10051.9 8187.3 FALSE FALSE TRUE 8842.451992 8393.583727 9197.278118 8651.852186 8864.323107 8104.93307 8489.80006 10936.71979 8949.231719 8471.808066 1.043750274 0.990766512 1.085633438 1.021252148 1.046331909 0.956694605 1.002123749 1.290954623 1.056354399 1 13.04845419 -4.259146559 24.94470757 1.019943175 1.29095472 0.838542456 0.035316807 53.80591094 585340.4852 0.004619972 0.041173275 5.51E-05 4.259146559 0.271011545 NFTKPQDGDVIAPLIT(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 2 NFTKPQDGDVIAPLITPQK 19 1 Q9Y3Z3-3;Q9Y3Z3-4;Q9Y3Z3 Q9Y3Z3-3 SAMHD1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 1 0 NFTKPQDGDVIAPLIT(1)PQK;NFTKPQDGDVIAPLIT(1)PQK ; 94.389 0.0012357 28023000 3018.7 4902.2 3489.9 3918 3059.1 4088 4004.5 2275.58 3993.3 3726.7 TRUE FALSE FALSE 2779.76671 5325.924324 3619.238764 3901.788354 3022.62223 3240.102719 4116.855492 2969.393867 3555.244981 3856.202548 0.720855991 1.381131893 0.938549964 1.011821424 0.783833887 0.840231466 1.067593168 0.770030575 0.921954938 1 11.91296512 -2.935381032 15.62171794 0.912158663 0.42393666 0 0.184655053 0 0 0.025234941 0 0.00116043 2.935381032 -0.488222003 NFTKPQDGDVIAPLIT(ph)PQKK ddPTM_HeLa_Curcumin_4h_R1 2 NFTKPQDGDVIAPLITPQKK 20 2 Q9Y3Z3-3;Q9Y3Z3-4;Q9Y3Z3 Q9Y3Z3-3 SAMHD1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 1 0 NFTKPQDGDVIAPLIT(1)PQKK;NFTKPQDGDVIAPLIT(1)PQKK ; 115.2 0.00030718 362570000 7772 5665.1 7328 5469.5 7310 9453 8421.2 6138.7 6947.2 6478.8 TRUE FALSE FALSE 7156.837999 6154.766001 7599.582126 5446.868658 7222.833024 7492.341243 8657.476208 8010.361371 6185.109541 6703.937818 1.067557336 0.918082203 1.133599734 0.812487945 1.077401554 1.117603034 1.291401627 1.194874056 0.922608429 1 12.71079305 -5.058651152 2.53744066 1.017047539 1.24173809 0.532854837 0.092786676 0.161433302 2.02306539 0.011765833 0.039513619 8.74E-06 5.058651152 0.224690551 NFTPPS(ph)PFANK ddPTM_HeLa_Curcumin_4h_R1 1 NFTPPSPFANK 11 0 Q9NPG3;Q9NPG3-2;K7EJT1 Q9NPG3 UBN1 Ubinuclein-1 1 0 NFT(0.451)PPS(0.549)PFANK 97.463 0.012638 10157000 1217.6 1017.5 1124 1098.7 1102.2 1693.7 1292 799.65 1384.4 906.45 TRUE FALSE FALSE 1121.225675 1105.448166 1165.656429 1094.153871 1089.056985 1342.407528 1328.250043 1043.459604 1232.534784 937.94907 1.195401447 1.178580161 1.24277156 1.16653868 1.161104605 1.431215799 1.416121712 1.112490685 1.314074317 1 9.873365777 -11.23779658 0.141154104 0.532390196 1.371996298 0 0.138150739 21.61748743 0.40363462 3.439608034 0.344519632 5.78E-12 11.23779658 0.839606101 S(ph)AS(ph)ASPLTPCSVTR ddPTM_HeLa_Curcumin_4h_R1 2 SASASPLTPCSVTR 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 0 S(1)AS(0.831)AS(0.169)PLTPCSVTR;S(0.998)AS(0.802)AS(0.192)PLT(0.006)PCS(0.001)VTR ; 189.99 1.66E-05 30601000 8294.2 6151.4 7085.1 7574.5 5563.3 7175.1 4622.6 1650.6 9760.8 6585.8 TRUE FALSE FALSE 7637.705318 6683.099606 7347.680039 7543.158726 5496.961281 5686.90338 4752.297715 2153.860342 8690.06466 6814.65606 1.120776346 0.980695071 1.078217297 1.106902338 0.80663811 0.834510697 0.69736428 0.316062956 1.275202238 1 12.73442513 -4.322236751 0.782324328 1.056317641 7.29E-17 0.848628938 0.100779533 0.521027674 0.239669841 0.012688689 0.469467486 4.76E-05 4.322236751 -1.056317641 down NFVVVMVTK ddPTM_HeLa_Curcumin_4h_R1 1 NFVVVMVTK 9 0 P54727;Q5W0S4;Q5W0S5;P54725-2;P54725-3;P54725;A0A494C0B4;K7ENJ0;K7ELW1 P54727;P54725-2 RAD23B;RAD23A UV excision repair protein RAD23 homolog B;UV excision repair protein RAD23 homolog A 0 0 107.15 0.0045504 343900 435.54 202.8 321.18 300.85 305.83 371.12 310.78 339.36 342.88 273.06 FALSE FALSE TRUE 401.0665494 220.3291283 333.0832133 299.6051624 302.183177 294.1455286 319.4996504 442.8293018 305.2669218 282.5488147 1.419459324 0.779791374 1.178851922 1.060366021 1.06949016 1.041043223 1.130776821 1.567266535 1.080404185 1 8.142356327 -4.260559317 23.67432846 1.141012812 1.567266779 0.415414764 0.159599906 34.39723874 924964.5543 0.026696071 0.216014436 5.49E-05 4.260559317 0.426253967 NFYES(ph)DDDQKEK ddPTM_HeLa_Curcumin_4h_R1 1 NFYESDDDQKEK 12 1 O00203-3;O00203 O00203-3 AP3B1 AP-3 complex subunit beta-1 1 0 NFYES(1)DDDQKEK 153.24 1.21E-05 0 1066.4 1109.3 1278.6 1071.5 1427.4 963.42 887.67 864.29 995.17 820.42 TRUE FALSE FALSE 981.9933147 1205.182949 1325.986041 1067.066417 1410.379187 763.595832 912.5756312 1127.808042 886.0023408 848.9295339 1.156743022 1.41965016 1.561950654 1.256955229 1.661361904 0.899480818 1.074972179 1.328506074 1.043670064 1 9.729500996 -7.703350119 1.91332281 1.052298062 1.307646963 0.229929417 0.209114728 0.345559969 2.638163587 0.043570577 0.043563969 1.98E-08 7.703350119 0.255348901 NFYQEHPDLAR ddPTM_HeLa_Curcumin_4h_R1 3 NFYQEHPDLAR 11 0 P17844-2;P17844;J3KTA4;J3QRQ7;J3QR02;J3KRX8;J3KTQ4;X6RLV5 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 0 ;; ;; 117.86 0.0035744 66320900 11095.5 9213.9 9901.4 9658.7 10141.1 12116.3 9879.7 8572.3 10848.2 10227.4 FALSE FALSE TRUE 10217.27947 10010.30846 10268.35459 9618.734859 10020.17401 9603.242801 10156.89779 11185.95481 9658.179601 10582.80139 0.96546076 0.945903461 0.970286998 0.908902521 0.946835685 0.907438631 0.959755118 1.056993739 0.91262977 1 13.36943396 -8.456227242 0.758232481 0.997376241 0.953288902 0 0.047277304 0.81806326 0.981668051 0.017525637 0.008817117 3.50E-09 8.456227242 -0.044087339 NFYVEHPEVAR ddPTM_HeLa_Curcumin_4h_R1 3 NFYVEHPEVAR 11 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 0 ;; ;; 134.75 0.0017027 22031100 15111 12996.4 13020.5 13857.2 14194.9 17830.2 13814 12687.6 16137.6 14885.4 FALSE FALSE TRUE 13914.9484 14119.75091 13503.05118 13799.86258 14025.63509 14132.01553 14201.58366 16555.99083 14367.34565 15402.66654 0.903411651 0.916708212 0.876669708 0.895939839 0.910597853 0.917504478 0.922021107 1.074878222 0.93278301 1 13.91089251 -3.078709487 16.43955714 0.941309518 0.931474942 0 0.056140883 0 0 0.008089032 0 0.000834239 3.078709487 -0.009834577 NGAGNGAK(ac)GK(ac)GK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 NGAGNGAKGKGKR 13 3 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 0 3 ; NGAGNGAK(1)GK(1)GK(1)R;NGAGNGAK(1)GK(1)GK(1)R 256.48 3.57E-93 2807700 142.58 301.93 404.71 54.585 0 477.4 301.15 880.45 177.21 167.878 FALSE TRUE FALSE 131.2946426 328.0274838 419.7089086 54.35914173 0 378.3818586 309.5994585 1148.895152 157.7705064 173.711748 0.755819017 1.888343693 2.416122763 0.312927262 0 2.178216862 1.782259761 6.613802262 0.908231643 1 7.440551516 -7.220652118 5.867896928 0.884382101 2.015282771 0.103860093 1.684880424 0.39039498 36.78740812 0.277171988 0.337301143 6.02E-08 7.220652118 1.13090067 NGDECAYHHPIS(ph)PCK ddPTM_HeLa_Curcumin_4h_R1 1 NGDECAYHHPISPCK 15 0 Q6PJT7;Q6PJT7-5;H0YJA2;Q6PJT7-9;Q6PJT7-2;Q6PJT7-3;Q6PJT7-11;Q6PJT7-4;G3V256;Q6PJT7-10;G3V5I6;G3V411;Q6PJT7-6;Q6PJT7-8;H0YJ51 Q6PJT7 ZC3H14 Zinc finger CCCH domain-containing protein 14 1 0 NGDECAYHHPIS(1)PCK 85.937 0.0039492 33716000 6946.5 5741.2 6142.7 6180.4 6299.3 7073.5 4770.9 3680.4 6508.5 5919.4 TRUE FALSE FALSE 6396.677195 6237.443746 6370.353866 6154.827142 6224.184962 5606.376365 4904.758614 4802.537018 5794.533833 6125.098709 1.04433863 1.018341751 1.040041013 1.004853543 1.016177087 0.915312003 0.800764012 0.78407504 0.946031094 1 12.58051738 -4.950078001 1.933836382 1.021995397 0.778775342 0.907929725 0.027493325 0.044165917 0.313116891 0.002629549 0.011768494 1.12E-05 4.950078001 -0.243220055 NGDLDEVKDYVAK ddPTM_HeLa_Curcumin_4h_R1 1 NGDLDEVKDYVAK 13 1 C9JL85;P58546 C9JL85 MTPN Myotrophin 0 0 104.59 0.0044898 17307000 1824.7 1951.6 1657.5 1911.6 1482 1728.4 1885.2 1894.5 1742.2 1878.5 FALSE FALSE TRUE 1680.27307 2120.287608 1718.928408 1903.690306 1464.328118 1369.910357 1938.093638 2472.124329 1551.085019 1943.777735 0.864436833 1.090807642 0.88432354 0.979376536 0.753341337 0.704766976 0.997075747 1.271814305 0.797974476 1 10.92464755 -4.309243338 3.966724508 0.918068111 1.289364004 0.489579034 0.115220465 0.142955537 4.223866337 0.015876326 0.13646542 4.91E-05 4.309243338 0.371295893 NGFVVLK ddPTM_HeLa_Curcumin_4h_R1 2 NGFVVLK 7 0 I3L397;I3L504;P63241;P63241-2;F8WCJ1;C9J7B5;C9J4W5;Q9GZV4;Q6IS14 I3L397 EIF5A;EIF5A2;EIF5AL1 Eukaryotic translation initiation factor 5A;Eukaryotic translation initiation factor 5A-1;Eukaryotic translation initiation factor 5A-2;Eukaryotic translation initiation factor 5A-1-like 0 0 ; ; 107.66 0.015435 20119500 12229 9002 10752.8 9740.5 11027.5 13722.9 10553.1 10273.9 11562.7 10064.3 FALSE FALSE TRUE 11261.06175 9780.092768 11151.30823 9700.196392 10896.00426 10876.61585 10849.19158 13406.36481 10294.30074 10414.03368 1.081335254 0.939126286 1.070796252 0.931454295 1.046280875 1.044419117 1.041785721 1.287336419 0.988502732 1 13.34624136 -4.258000862 4.502994333 1.028026178 1.305299234 0.723861738 0.049854385 0.083605066 4.259042952 0.006823439 0.073469119 5.52E-05 4.258000862 0.277273057 NGFVVLK(ac)GRPCK ddPTM_HeLa_Curcumin_4h_R1 2 NGFVVLKGRPCK 12 2 I3L397;I3L504;P63241;P63241-2;F8WCJ1;C9J7B5;C9J4W5;Q9GZV4 I3L397 EIF5A;EIF5A2 Eukaryotic translation initiation factor 5A;Eukaryotic translation initiation factor 5A-1;Eukaryotic translation initiation factor 5A-2 0 1 ; NGFVVLK(1)GRPCK;NGFVVLK(1)GRPCK 93.839 0.0035945 12344900 3586 3195.2 3167.8 3598.1 3326.2 5153 4284.4 4544.6 4778.9 4777.6 FALSE TRUE FALSE 3302.164316 3471.37885 3285.201455 3583.212016 3286.537237 4084.209714 4404.608733 5930.227619 4254.666626 4943.621244 0.667964667 0.70219353 0.664533404 0.724815239 0.664803608 0.826157489 0.890968081 1.199571595 0.860637661 1 12.2713525 -4.241907852 2.143447607 0.795117227 1.321442665 0.600901947 0.105239424 0.570317134 2.776595393 0.021274132 0.584518474 5.73E-05 4.241907852 0.526325439 NGGHFVISIK ddPTM_HeLa_Curcumin_4h_R1 1 NGGHFVISIK 10 0 M0R0P1;M0R299;M0QXL5;M0R2Q4;P22087 M0R0P1 FBL rRNA 2-O-methyltransferase fibrillarin 0 0 72.2 0.01981 4604100 7339.9 5193.3 5623 6148.3 6135.8 6958.4 5668.8 4819 6359.3 5777.1 FALSE FALSE TRUE 6758.93917 5642.185711 5831.393326 6122.859964 6062.634592 5515.149403 5827.851271 6288.290916 5661.7007 5977.853795 1.130663178 0.943848061 0.97549949 1.024257229 1.014182481 0.922596904 0.97490696 1.0519312 0.947112608 1 12.5454119 -7.248537839 24.99428977 1.061702058 0.985888849 0 0.058591484 771.9835593 1495573.18 0.009804634 0.011969306 5.64E-08 7.248537839 -0.075813209 NGGK(ac)LSNDHQQNQSK ddPTM_HeLa_Curcumin_4h_R1 1 NGGKLSNDHQQNQSK 15 1 C9JP58;F8WFA4;B7WNX0;B5MCB3;Q4FZB7-4;Q4FZB7-2;Q4FZB7 C9JP58 SUV420H1 Histone-lysine N-methyltransferase SUV420H1 0 1 NGGK(1)LSNDHQQNQSK 159.41 0.0019385 930080 276.02 440.05 399.26 440.42 678.02 984.68 567.93 102.37 889.47 397.97 FALSE TRUE FALSE 254.1727257 478.0859612 414.0569268 438.5976587 669.9350543 780.4462684 583.8645873 133.5821417 791.8973663 411.7994279 0.617224572 1.160968007 1.005482035 1.06507593 1.626847948 1.895209696 1.417837296 0.324386419 1.92301716 1 8.685798015 -6.462072906 1.467553832 0.83206093 1.342068923 0 0.531046586 0.447587118 1.914900137 0.070572942 0.119581523 3.45E-07 6.462072906 0.510007993 NGGSMTLRPDALR ddPTM_HeLa_Curcumin_4h_R1 1 NGGSMTLRPDALR 13 1 A0A286YFD0 A0A286YFD0 0 0 114.4 0.014147 1676400 773.68 941.46 1034.7 943.29 1081.9 1352 1124.3 981.54 1116.6 835.58 FALSE FALSE TRUE 712.4424116 1022.835607 1073.046892 939.3869159 1068.999049 1071.57996 1155.844832 1280.807028 994.1117736 864.6163428 0.823998317 1.182993608 1.241067094 1.086478325 1.23638543 1.239370466 1.33682973 1.481358799 1.149772129 1 9.755916296 -5.970508602 0.553966046 0.918587854 1.424921042 0.480334717 0.123731954 0.466628512 0.249939437 0.02949531 0.110638882 1.07E-06 5.970508602 0.506333188 NGHVGISFVPK ddPTM_HeLa_Curcumin_4h_R1 1 NGHVGISFVPK 11 0 P21333-2;P21333;Q60FE5 P21333-2;Q60FE5 FLNA Filamin-A 0 0 94.82 0.0044769 11825000 8841.8 7997.1 7080.8 6603.4 10753 15721 9359.9 7349.2 10418 7665.2 FALSE FALSE TRUE 8141.9622 8688.33369 7343.220677 6576.07688 10624.7775 12460.28739 9622.513603 9589.937248 9275.171465 7931.565129 1.026526551 1.095412261 0.925822402 0.829102046 1.339556232 1.570974604 1.213192282 1.209085104 1.169399899 1 12.95338986 -5.7418295 24.97755935 1.001035899 1.341613853 0.613574987 0.126407711 108.0307205 137600.4931 0.01663671 0.03323571 1.81E-06 5.7418295 0.340577954 NGIDILVGT(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 1 NGIDILVGTPGR 12 0 Q9NR30;Q9NR30-2;A0A087WVC1;Q9BQ39 Q9NR30;A0A087WVC1 DDX21;DDX50 Nucleolar RNA helicase 2;ATP-dependent RNA helicase DDX50 1 0 NGIDILVGT(1)PGR 137.73 0.0042796 7251200 4298.6 3860.7 3871.6 4690.5 4374.9 6218.5 5325.5 3128.7 4067.6 3612.4 TRUE FALSE FALSE 3958.361274 4194.401705 4015.084902 4671.091954 4322.732175 4928.713003 5474.919197 4082.626227 3621.394457 3737.930631 1.058971304 1.122118658 1.074146446 1.249646506 1.156450614 1.318567274 1.464692563 1.092215621 0.968823345 1 11.86802408 -6.288264896 0.687075756 1.019556419 1.307747858 0.556695713 0.096690697 0.357778164 0.32995503 0.019070275 0.047436306 5.15E-07 6.288264896 0.288191439 VTSSMSS(ph)PSMQPK ddPTM_HeLa_Curcumin_4h_R1 1 VTSSMSSPSMQPK 13 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 0 VTS(0.001)S(0.007)MS(0.203)S(0.752)PS(0.037)MQPK 109.16 0.0018329 76350000 4930.6 3816.1 4245.2 4579.3 4467.1 4585.6 2970 750.87 4369.1 3915 TRUE FALSE FALSE 4540.337807 4145.94668 4402.530846 4560.35207 4413.83275 3634.49487 3053.330207 979.8068064 3889.820661 4051.045959 1.120781609 1.023426227 1.086763984 1.125722126 1.089553857 0.897174435 0.753714038 0.241865142 0.960201563 1 11.98407874 -4.321618355 1.408879733 1.063942008 2.24E-22 0.946181626 0.058915856 0.168497016 0.319723202 0.008621399 0.244209117 4.77E-05 4.321618355 -1.063942008 down NGIGPGSHSEFAASIGS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 NGIGPGSHSEFAASIGSPK 19 0 Q9H694;Q9H694-2;A6NGY7 Q9H694 BICC1 Protein bicaudal C homolog 1 1 0 NGIGPGSHSEFAAS(0.252)IGS(0.748)PK 148.66 4.61E-10 0 1105.4 1258.1 908.64 1048.9 1143.7 1338.4 865.01 491.59 1354.2 967.32 TRUE FALSE FALSE 1017.906424 1366.844558 942.3149977 1044.55993 1130.062124 1060.800753 889.2798525 641.473528 1205.647648 1000.934298 1.016956283 1.36556871 0.941435416 1.04358491 1.129007295 1.059810574 0.888449776 0.64087476 1.204522265 1 9.967131562 -4.386026652 2.378837134 1.042830851 0.600160458 0.545682828 0.123238739 0.246509722 2.001647644 0.015792014 0.198601446 4.11E-05 4.386026652 -0.442670393 NGNTQY(ph)LVRWK ddPTM_HeLa_Curcumin_4h_R1 1 NGNTQYLVRWK 11 1 C9JMH9;Q9Y6F8;Q9Y6F7;Q9Y6F8-2 C9JMH9 CDY2A;CDY1 Testis-specific chromodomain protein Y 1;Testis-specific chromodomain protein Y 2 1 0 NGNT(0.309)QY(0.691)LVRWK 50.791 0.019289 26903000 4235.9 3593.8 4513 4268.9 3550.8 3485.5 4878.5 4189.6 3817.7 4121 TRUE FALSE FALSE 3900.624045 3904.432058 4680.25575 4251.236423 3508.459029 2762.56801 5015.37758 5466.989753 3398.907861 4264.204443 0.91473664 0.915629659 1.09756833 0.996958865 0.822769892 0.647850741 1.176157862 1.282065583 0.797079011 1 12.05806089 -4.541782849 24.95712594 0.940767685 1.25558882 0.51826032 0.123948845 116.9796816 154436.0891 0.016350828 0.061197261 2.87E-05 4.541782849 0.314821135 NGQIDK(ac)EAVQK ddPTM_HeLa_Curcumin_4h_R1 1 NGQIDKEAVQK 11 1 Q01813;Q01813-2;Q5VSR5 Q01813 PFKP "ATP-dependent 6-phosphofructokinase, platelet type" 0 1 NGQIDK(1)EAVQK 143.79 3.49E-17 0 394.8 572.75 487.07 437.5 984.73 1114 649.26 432.95 959.46 420.39 FALSE TRUE FALSE 363.5511634 622.2559579 505.1212427 435.6897409 972.9877379 882.9438426 667.4764882 564.9544619 854.2096385 434.9985212 0.835752642 1.430478329 1.161202207 1.001589016 2.236761024 2.02976286 1.534433925 1.298750305 1.963706994 1 8.764866686 -5.786296975 24.33848382 0.987813049 1.775951339 0.165118763 0.42007898 82.2903767 80571.68874 0.044872702 0.081367455 1.64E-06 5.786296975 0.78813829 NGS(ph)EADIDEGLYSR ddPTM_HeLa_Curcumin_4h_R1 4 NGSEADIDEGLYSR 14 0 P22314;P22314-2;Q5JRR9;Q5JRS0;Q5JRS2;Q5JRS1;Q5JRS3 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 1 0 NGS(1)EADIDEGLYSR;NGS(1)EADIDEGLYSR;NGS(1)EADIDEGLYSR;NGS(1)EADIDEGLYSR ;;; 208.49 2.48E-09 133527000 6671.52 4996.1 5843.15 5710.05 5628.52 6776.43 5523.92 6481.32 5957.93 6441.55 TRUE FALSE FALSE 6143.462152 5427.940622 6059.702279 5686.423326 5561.403575 5370.922032 5678.906328 8457.444632 5304.359985 6665.393383 0.92169536 0.814346627 0.909128979 0.85312644 0.834369895 0.805792205 0.851998675 1.268859037 0.795805991 1 12.70247431 -8.462403405 0.977619731 0.989931208 0.89583515 0 0.141379503 0.908002293 1.783582038 0.04305671 0.025221485 3.45E-09 8.462403405 -0.094096058 ASTVS(ph)PGGYMVPK ddPTM_HeLa_Curcumin_4h_R1 4 ASTVSPGGYMVPK 13 0 Q5TGY3 Q5TGY3 AHDC1 AT-hook DNA-binding motif-containing protein 1 1 0 AST(0.008)VS(0.991)PGGYMVPK;AST(0.014)VS(0.986)PGGYMVPK;AS(0.001)T(0.028)VS(0.971)PGGYMVPK;AS(0.003)T(0.052)VS(0.945)PGGYMVPK ;;; 166.62 0.00018266 61918700 11733.3 10334.4 10178.6 10749.5 9942.3 12721.2 7046.1 2206.85 12523.8 9324.4 TRUE FALSE FALSE 10804.59692 11227.65949 10555.82787 10705.02142 9823.744566 10082.67972 7243.794602 2879.708406 11149.97047 9648.422206 1.119830444 1.163678293 1.094047052 1.109510051 1.018171091 1.045008138 0.750775044 0.298464178 1.155626302 1 13.23607732 -4.318947588 1.650488039 1.071893298 0.07154159 0.95487212 0.05360862 0.142286085 0.402121872 0.008731714 0.217698879 4.80E-05 4.318947588 -1.000351707 down NGS(ph)PNKQPSSEPEWTPEPR ddPTM_HeLa_Curcumin_4h_R1 1 NGSPNKQPSSEPEWTPEPR 19 1 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 NGS(0.979)PNKQPS(0.015)S(0.002)EPEWT(0.005)PEPR 60.991 0.0092312 46210000 968.98 888.49 1332.9 1238.9 1103.4 1270.2 1145.5 701.52 1177.2 1101.4 TRUE FALSE FALSE 892.2842105 965.2871166 1382.298447 1233.77376 1090.242676 1006.746202 1177.639647 915.4102186 1048.064105 1139.673568 0.782929635 0.846985614 1.2128898 1.082567671 0.956627149 0.883363649 1.033313117 0.803221417 0.919617805 1 10.15440494 NGS(ph)PTPAGSLGGGAVATAGGPGSR ddPTM_HeLa_Curcumin_4h_R1 1 NGSPTPAGSLGGGAVATAGGPGSR 24 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 0 NGS(0.747)PT(0.253)PAGSLGGGAVATAGGPGSR 132.24 1.67E-06 31488000 1231.4 988.03 1021.3 1157.7 1141.3 996.63 918.2 675.9 1314.8 1138.9 TRUE FALSE FALSE 1133.933391 1073.430911 1059.150276 1152.909744 1127.690743 789.9177037 943.9622208 881.9787985 1170.569729 1178.47669 0.962202647 0.910863082 0.898745207 0.97830509 0.956905429 0.670287083 0.80100203 0.748405807 0.993290524 1 10.20270751 -5.276715175 23.50881489 0.968115736 0.746008695 0.839544005 0.043322915 98.03770433 150876.0668 0.006548892 0.014706706 5.29E-06 5.276715175 -0.222107041 NGSEADIDEGLYSR ddPTM_HeLa_Curcumin_4h_R1 2 NGSEADIDEGLYSR 14 0 P22314;P22314-2;Q5JRR9;Q5JRS0;Q5JRS2;Q5JRS1;Q5JRS3 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 0 ; ; 190.57 5.62E-05 22919000 3191.3 2861.3 3326.7 3154.8 3030.6 3769.3 3188 3133.6 4018.5 3257.1 FALSE FALSE TRUE 2938.705238 3108.618022 3449.990428 3141.746274 2994.462074 2987.504691 3277.4467 4089.020215 3577.680604 3370.283983 0.871945881 0.922360857 1.023649771 0.93219037 0.888489543 0.886425211 0.972454166 1.213256876 1.061536839 1 11.71865444 -4.272459099 3.811548927 0.935883033 1.238190799 0.624873004 0.060556738 0.107993225 3.043670495 0.007987363 0.089641389 5.34E-05 4.272459099 0.302307766 LTLDK(ac)LDVK ddPTM_HeLa_Curcumin_4h_R1 2 LTLDKLDVK 9 1 P00558 P00558 PGK1 Phosphoglycerate kinase 1 0 1 ; LTLDK(1)LDVK;LTLDK(1)LDVK 120.68 0.0012777 13510800 1155.65 1028.36 1075.59 924.94 1792.39 2493.7 1877.33 2189.41 1990.8 920.65 FALSE TRUE FALSE 1064.179083 1117.246856 1115.452312 921.1128434 1771.01692 1976.47851 1930.002827 2856.95103 1772.414221 952.642519 1.117081237 1.172787099 1.170903345 0.966902931 1.859057185 2.074732621 2.025946553 2.998974928 1.860523948 1 9.895791131 -3.890551658 0.493663261 1.028565235 4.959285257 0.723176845 0.326608562 1.137611752 0.144004787 0.039567812 2.804212455 0.000128661 3.890551658 3.930720022 up NGSLDS(ph)PGKQDTEEDEEEDEKDK ddPTM_HeLa_Curcumin_4h_R1 1 NGSLDSPGKQDTEEDEEEDEKDK 23 2 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 1 0 NGS(0.04)LDS(0.777)PGKQDT(0.183)EEDEEEDEKDK 81.017 0.00037322 12816000 1310.6 1141.2 1450.6 1205.1 1636.2 1698 1462 1397.4 1349.6 1133.8 TRUE FALSE FALSE 1206.864627 1239.840243 1504.360512 1200.113616 1616.689384 1345.81566 1503.019785 1823.460827 1201.552257 1173.199466 1.028695173 1.056802598 1.282271733 1.022940813 1.378017491 1.147132861 1.281128938 1.554263261 1.024167068 1 10.1962326 -1 0.250481302 0.98547072 4.170400506 0.662564931 0.103980014 18.50059109 0.23096551 0.052059687 25.13911598 0.1 1 3.184929787 NGSLDSPGKQDT(ph)EEDEEEDEKDK ddPTM_HeLa_Curcumin_4h_R1 1 NGSLDSPGKQDTEEDEEEDEKDK 23 2 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 1 0 NGS(0.002)LDS(0.148)PGKQDT(0.85)EEDEEEDEKDK 86.959 0.00064853 9031000 1503.9 1467.5 1601.8 1200.9 2253.3 1959.7 1624.7 1716.2 1303.8 1369.8 TRUE FALSE FALSE 1384.864728 1594.344161 1661.164117 1195.930994 2226.430869 1553.23613 1670.284709 2239.46148 1160.776402 1417.400448 0.977045499 1.124836784 1.171979393 0.843749553 1.570784652 1.095834372 1.178414125 1.579977968 0.818947393 1 10.46903169 -1.000000005 0.284949594 0.975573667 4.907763335 0.450459133 0.184686026 31.9102219 0.407334721 0.068459715 63.70298674 0.099999999 1.000000005 3.932189668 DRSWVIGS(ph)PEILR ddPTM_HeLa_Curcumin_4h_R1 1 DRSWVIGSPEILR 13 1 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 0 DRS(0.002)WVIGS(0.998)PEILR 79.013 0.010078 8192700 1804 1600.9 1601 1744 1658.1 1847 1059.6 419.69 2199 1772.7 TRUE FALSE FALSE 1661.211496 1739.274663 1660.334468 1736.78379 1638.32824 1463.91138 1089.329524 547.651549 1957.775202 1834.301193 0.905637255 0.948194696 0.905159128 0.946836755 0.893162064 0.798075793 0.593866225 0.298561409 1.067313923 1 10.84101483 -4.318617077 1.005080124 0.950875324 1.58E-13 0.957085882 0.044770921 0.199186053 0.164397092 0.005704061 0.198931564 4.80E-05 4.318617077 -0.950875324 down NGSNPETTTSGGCHS(ph)PEDIQDILK ddPTM_HeLa_Curcumin_4h_R1 1 NGSNPETTTSGGCHSPEDIQDILK 24 0 B7ZC06 B7ZC06 GOLGA2 1 0 NGS(0.003)NPET(0.022)T(0.015)T(0.015)S(0.042)GGCHS(0.903)PEDIQDILK 80.453 0.00011653 6825500 1211.2 1072.1 775.32 970.34 1370.4 1577.2 1125.3 1177.4 1276 1247.9 TRUE FALSE FALSE 1115.332242 1164.767547 804.0540412 966.3249902 1354.058875 1250.070941 1156.872889 1536.38384 1136.025992 1291.264432 0.863752005 0.902036421 0.622687361 0.748355617 1.048630196 0.968098331 0.895922524 1.189828978 0.879777963 1 10.33456876 -1.847578206 1.322115662 0.903364795 199.9999996 0.358489752 0.119056091 1029.168586 3.258211497 0.019245901 619831.8306 0.014204364 1.847578206 199.0966348 NGSTAVAESVAS(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 4 NGSTAVAESVASPQK 15 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 NGSTAVAESVAS(1)PQK;NGSTAVAESVAS(1)PQK;NGSTAVAESVAS(1)PQK;NGSTAVAESVAS(1)PQK ;;; 203.92 1.96E-09 137240000 23397.2 19009.4 20276.6 21375.5 21967.5 24336.5 19743.6 16740.6 22639.7 20062.5 TRUE FALSE FALSE 21545.28693 20652.48783 21028.06863 21287.05384 21705.55191 19288.83557 20297.55228 21844.73188 20156.18155 20759.67038 1.037843402 0.994836982 1.01292883 1.025404231 1.045563417 0.929149414 0.977739622 1.052267761 0.970929749 1 14.34149592 -5.310472275 24.99990901 1.018279835 0.985520554 0.090471073 0.034678112 466.5366095 237867.8174 0.004487492 0.010034376 4.89E-06 5.310472275 -0.032759281 NGTGGLFQGK(ac)TPLR ddPTM_HeLa_Curcumin_4h_R1 1 NGTGGLFQGKTPLR 14 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 0 1 NGTGGLFQGK(1)TPLR 130.2 0.0017886 1536000 205.07 263.7 160.55 113.5 216.36 148.06 132.21 195.41 157.04 196.96 FALSE TRUE FALSE 188.8384931 286.493053 166.5001242 113.0303671 213.7800483 117.350687 135.9194568 254.9896094 139.8131049 203.8043453 0.926567551 1.40572593 0.81696062 0.554602341 1.04894745 0.575800711 0.666911476 1.251149032 0.68601631 1 7.671041001 -6.562310583 24.99945775 1.002811422 0.797771669 0.107998562 0.257427155 215.8332209 136835.7235 0.035355999 0.050000972 2.74E-07 6.562310583 -0.205039753 NGTSGSDS(ph)PGQAVEAEEIVK ddPTM_HeLa_Curcumin_4h_R1 2 NGTSGSDSPGQAVEAEEIVK 20 0 Q05D32 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 0 NGTS(0.006)GS(0.095)DS(0.898)PGQAVEAEEIVK;NGTSGSDS(1)PGQAVEAEEIVK ; 266.53 4.25E-105 2911500 3812.8 3264.5 3173.3 3464.9 3834.4 4904.8 3231.5 2480.5 4070.8 3188.4 TRUE FALSE FALSE 3511.012857 3546.668834 3290.90529 3450.563162 3788.677284 3887.489192 3322.167193 3236.793031 3624.243425 3299.196663 1.064202355 1.075009827 0.997486851 1.045879805 1.148363578 1.178313871 1.006962462 0.981085204 1.098523003 1 11.68789906 -9.326915141 0.487021709 0.983284262 1.06795084 0 0.066930436 2.947696705 0.909968447 0.122226153 0.017343123 4.71E-10 9.326915141 0.084666578 NGVAAEVS(ph)PAKEENPR ddPTM_HeLa_Curcumin_4h_R1 4 NGVAAEVSPAKEENPR 16 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 0 NGVAAEVS(1)PAKEENPR;NGVAAEVS(1)PAKEENPR;NGVAAEVS(1)PAKEENPR;NGVAAEVS(1)PAKEENPR ;;; 95.5 0.0017823 376972000 9939.9 9370.4 8796.1 10613.8 10371.1 11540.9 9627.2 9900.6 10810.9 9944.3 TRUE FALSE FALSE 9153.146426 10180.33562 9122.091204 10569.88291 10247.43141 9147.187247 9897.313322 12919.24736 9624.971318 10289.86368 0.889530387 0.989355732 0.886512347 1.027213113 0.995876303 0.888951256 0.961850771 1.255531439 0.935383754 1 13.32893625 -4.262848893 5.883121379 0.950496304 1.264164805 0.776733826 0.048723503 0.05051155 7.97195555 0.007429317 0.063295558 5.46E-05 4.262848893 0.313668501 NGYGFVEFDDLRDADDAVYELNGK ddPTM_HeLa_Curcumin_4h_R1 1 NGYGFVEFDDLRDADDAVYELNGK 24 1 Q08170;A0A0D9SEM4 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 0 0 119.94 6.92E-07 4536900 838.49 651.56 733.77 715.33 690.24 1237.8 684.28 1128.4 994.42 801.76 FALSE FALSE TRUE 772.1226317 707.8779431 760.9641617 712.370154 682.0093388 981.0663271 703.4790552 1472.443965 885.3346139 829.6211003 0.930693098 0.853254507 0.917243018 0.858669281 0.82207328 1.182547463 0.847952222 1.774839098 1.067155372 1 9.696308777 -4.257250855 24.98538278 0.947191373 1.774839426 0.843302396 0.107659174 105.999076 632281.2749 0.013315773 0.13778274 5.53E-05 4.257250855 0.827648053 NGYGFVEFEDS(ph)RDADDAVYELNGK ddPTM_HeLa_Curcumin_4h_R1 2 NGYGFVEFEDSRDADDAVYELNGK 24 1 Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80;Q13247-2 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 1 0 NGY(0.001)GFVEFEDS(0.989)RDADDAVY(0.011)ELNGK;NGY(0.001)GFVEFEDS(0.978)RDADDAVY(0.021)ELNGK ; 68.552 0.00050644 17777100 2636.1 2363.21 2792.43 2921.9 2955.72 3182.25 2808.35 3027.63 2637.33 2551.26 TRUE FALSE FALSE 2427.449903 2567.475342 2895.919912 2909.809952 2920.474969 2522.215479 2887.144743 3950.74045 2348.021497 2639.916095 0.919517824 0.972559449 1.096974225 1.102235771 1.106275679 0.955415016 1.093650191 1.496540158 0.88943035 1 11.36627636 NGYGFVEFEDSRDADDAVYELNGK ddPTM_HeLa_Curcumin_4h_R1 1 NGYGFVEFEDSRDADDAVYELNGK 24 1 Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80;Q13247-2 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 0 0 163.49 7.97E-09 7741800 1471.4 1140.7 1387.6 1505 1335.2 1826.1 1339.4 1536.1 1346.2 1232.7 FALSE FALSE TRUE 1354.937137 1239.297025 1439.025677 1498.772709 1319.278612 1447.346276 1376.979959 2004.449819 1198.525228 1275.536233 1.062249039 0.971589041 1.128173108 1.175013825 1.034293325 1.134696324 1.079530258 1.571456589 0.939624604 1 10.31688817 -1.930914694 1.24492206 1.045394355 199.985213 0.815562817 0.072797645 159.2239218 0.835614432 0.009930787 89806.25577 0.011724256 1.930914694 198.9398186 NHAGS(ph)PGCEESDAGKEK ddPTM_HeLa_Curcumin_4h_R1 1 NHAGSPGCEESDAGKEK 17 1 P42575 P42575 CASP2 Caspase-2;Caspase-2 subunit p18;Caspase-2 subunit p13;Caspase-2 subunit p12 1 0 NHAGS(1)PGCEESDAGKEK 103.31 0.00070558 8012100 998.59 1162.3 889.21 1026.7 1082.4 1416.4 1064.5 561.69 1098 958.93 TRUE FALSE FALSE 919.5505478 1262.764033 922.1649048 1022.451787 1069.493087 1122.622674 1094.367005 732.9466953 977.5521471 992.2527461 0.926730162 1.272623369 0.929364931 1.030434828 1.077843414 1.131387823 1.102911541 0.738669354 0.985184622 1 9.95456384 NHDDWSHDYDNRR ddPTM_HeLa_Curcumin_4h_R1 2 NHDDWSHDYDNRR 13 1 G3V1T9;J3KPD3;Q9Y580 G3V1T9 RBM7 RNA-binding protein 7 0 0 ; ; 92.247 0.0027269 8918300 1644.38 1092.96 1162.93 1388.23 1469.38 1718.73 1198.24 1011.48 1837.07 1323.86 FALSE FALSE TRUE 1514.225588 1187.430592 1206.029209 1382.485872 1451.858603 1362.246024 1231.85939 1319.875596 1635.548017 1369.864036 1.105383854 0.866823685 0.880400665 1.009213933 1.059855989 0.994438855 0.899256683 0.963508466 1.193949161 1 10.41981699 -7.274623509 24.99374156 1.049764596 0.956294649 0.390722844 0.07642638 761.026131 1442708.31 0.012214573 0.014010949 5.31E-08 7.274623509 -0.093469947 NHETDGGS(ph)AHGDDDDDGPHFEPVVPLPDKIEVK ddPTM_HeLa_Curcumin_4h_R1 1 NHETDGGSAHGDDDDDGPHFEPVVPLPDKIEVK 33 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 NHET(0.299)DGGS(0.701)AHGDDDDDGPHFEPVVPLPDKIEVK 42.344 0.0077199 12274000 2358.9 1937.4 1860.6 2122.2 2384.4 2944 1658.3 948.35 2959.7 2236.8 TRUE FALSE FALSE 2172.190576 2104.860223 1929.555473 2113.418899 2355.967587 2333.381214 1704.827435 1237.497549 2635.028315 2314.528634 0.938502356 0.909412047 0.833671031 0.913109852 1.017903841 1.008145322 0.736576515 0.534665042 1.138472982 1 11.1765027 -4.524939789 3.034839912 0.95724442 0.54627872 0.75578747 0.079483315 0.077819276 1.344613919 0.008798798 0.056599518 2.99E-05 4.524939789 -0.4109657 NHLLQFALES(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 1 NHLLQFALESPAK 13 0 Q9NS91;F8WE49 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 0 NHLLQFALES(1)PAK 90.229 0.012229 25539000 3822.3 3703.5 3615.1 3928.4 4201.1 5509.6 4016.4 2619.8 4220.9 4046.5 TRUE FALSE FALSE 3519.760922 4023.614038 3749.078786 3912.145322 4151.004626 4366.846854 4129.089374 3418.56496 3757.87783 4187.115574 0.840617093 0.960951272 0.895384596 0.934329433 0.991375698 1.042924843 0.986141725 0.816448674 0.897486053 1 12.03174102 -5.929904001 7.37837446 0.923722358 0.966907611 0.067667854 0.067074415 0.566362463 50.47966604 0.011694772 0.021271985 1.18E-06 5.929904001 0.043185253 NHLLQFALES(ph)PAKSPASSSSK ddPTM_HeLa_Curcumin_4h_R1 2 NHLLQFALESPAKSPASSSSK 21 1 Q9NS91;F8WE49 Q9NS91 RAD18 E3 ubiquitin-protein ligase RAD18 1 0 NHLLQFALES(0.995)PAKS(0.002)PAS(0.001)SSSK;NHLLQFALES(1)PAKSPASSSSK ; 77.838 0.00062226 69573000 5121.3 4496.6 4234 4417.7 3808.7 5158.2 3851.9 2446.8 5123.5 5863.7 TRUE FALSE FALSE 4715.943701 4885.266068 4390.915765 4399.420728 3763.28374 4088.331175 3959.973947 3192.818056 4561.464868 6067.463139 0.777251315 0.805157931 0.723682314 0.725084047 0.620240066 0.673812281 0.652657273 0.526219605 0.751791113 1 12.56687772 -12.91891935 0.053111691 2.329116233 7.92E-16 0.507036716 0.084206343 50.33364637 0.236037434 9.954341259 2.611472168 1.21E-13 12.91891935 -2.329116233 NHLS(ph)PQQGGATPQVPS(ph)PCCR ddPTM_HeLa_Curcumin_4h_R1 2 NHLSPQQGGATPQVPSPCCR 20 0 Q9H4L4;A0A087X0R7 Q9H4L4 SENP3;SENP3-EIF4A1 Sentrin-specific protease 3 2 0 NHLS(1)PQQGGATPQVPS(1)PCCR;NHLS(1)PQQGGATPQVPS(1)PCCR ; 118.61 0.0002669 17875000 2072.3 1810.15 1700.09 2085.5 1974.3 2372 1466.67 1042.83 2611.6 2221.5 TRUE FALSE FALSE 1908.275268 1966.6113 1763.096831 2076.870754 1950.757762 1880.020462 1507.820813 1360.784066 2325.114014 2298.69696 0.830155215 0.855533084 0.766998374 0.903499152 0.848636334 0.817863553 0.655945886 0.591980627 1.011492187 1 11.16660057 -2.022238403 0.136222721 1.03185255 2.65E-25 0.746530775 0.063538092 26.48158976 0.312774121 0.229223518 5.098532813 0.009500831 2.022238403 -1.03185255 NHS(ph)RKT(ph)PVIST(ph)K ddPTM_HeLa_Curcumin_4h_R1 2 NHSRKTPVISTK 12 2 H3BQT6 H3BQT6 PTPN9 3 0 NHS(1)RKT(0.892)PVIS(0.111)T(0.998)K;NHS(0.999)RKT(0.869)PVIS(0.133)T(0.999)K ; 78.401 0.010652 51470000 3283.5 2965.8 2838.1 3122 2975.6 3173.5 2862.5 2562.9 3186.4 2686.1 TRUE FALSE FALSE 3023.60751 3222.150537 2943.282483 3109.081991 2940.117913 2515.280327 2942.814046 3344.316412 2836.859892 2779.441775 1.087847041 1.159279739 1.058947343 1.118599432 1.05780878 0.904958812 1.058778807 1.203233125 1.020658147 1 11.44057944 -9.202825401 1.039407303 1.001743772 1.076685617 0.121951851 0.074542248 0.868132284 1.739879621 0.045121892 0.013882914 6.27E-10 9.202825401 0.074941845 NHSDSSTSESEVS(ph)SVSPLK ddPTM_HeLa_Curcumin_4h_R1 1 NHSDSSTSESEVSSVSPLK 19 0 Q9NY27-2;Q9NY27-3;Q9NY27;H7C559;C9IZ04 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 0 NHSDSSTS(0.001)ESEVS(0.758)S(0.24)VS(0.001)PLK 186.88 2.92E-08 26164000 2094.2 1814.8 1302 1170.5 4329.8 5191.3 2856.8 1842.9 1910.9 1446.3 TRUE FALSE FALSE 1928.44186 1971.663225 1350.253265 1165.656781 4278.169963 4114.565862 2936.954119 2404.791726 1701.279051 1496.558817 1.288584076 1.317464574 0.902238689 0.778891392 2.858671449 2.749351255 1.962471562 1.606880865 1.136793978 1 10.54743327 -5.767986701 24.99991563 1.112708315 2.303139189 0.726260967 0.367481363 64.64827479 246850.2125 0.056925389 0.104959517 1.71E-06 5.767986701 1.190430875 NHSDSSTSESEVSSVS(ph)PLK ddPTM_HeLa_Curcumin_4h_R1 3 NHSDSSTSESEVSSVSPLK 19 0 Q9NY27-2;Q9NY27-3;Q9NY27;H7C559;C9IZ04 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 1 0 NHSDSSTSESEVSS(0.008)VS(0.992)PLK;NHSDSSTSESEVS(0.032)S(0.054)VS(0.913)PLK;NHSDSSTS(0.009)ESEVS(0.241)S(0.241)VS(0.508)PLK ;; 232.54 3.39E-25 44664800 5363.3 4936.7 3836.01 4131.4 11301.8 13080.3 7128.2 5034.86 5814.3 4326.06 TRUE FALSE FALSE 4938.789146 5363.40635 3978.175905 4114.305361 11167.03342 10367.29833 7328.198107 6569.965636 5176.485837 4476.390263 1.103297268 1.198154324 0.88870176 0.919112302 2.49465144 2.315995194 1.637077573 1.467692773 1.15639735 1 12.1281201 -5.777017503 24.9999995 1.040918926 1.978523149 0.714049484 0.289730937 96.30361776 154549.3629 0.043783134 0.079563507 1.67E-06 5.777017503 0.937604223 NHSGNDERDEEDEER ddPTM_HeLa_Curcumin_4h_R1 1 NHSGNDERDEEDEER 15 1 A0A0D9SGE8;Q8IWS0-3;Q8IWS0-5;Q8IWS0 A0A0D9SGE8;Q8IWS0-5 PHF6 PHD finger protein 6 0 0 89.46 0.0037501 2099800 178.01 152.75 192.15 102.11 240.13 206.87 278.25 149.62 178.42 186.03 FALSE FALSE TRUE 163.9203207 165.9530294 199.271248 101.6874959 237.2666066 163.9628301 286.0569461 195.2384492 158.8477724 192.4945287 0.851558337 0.862118163 1.035204738 0.528261746 1.232588834 0.851779171 1.486052347 1.014254538 0.825206688 1 7.58867363 -4.78089835 24.99671473 0.919930005 1.250153573 0.324875876 0.200945208 168.4424301 216379.3039 0.024830739 0.074647739 1.66E-05 4.78089835 0.330223568 NHSVNEEEQEEQGEGS(ph)EDEWEQVGPR ddPTM_HeLa_Curcumin_4h_R1 3 NHSVNEEEQEEQGEGSEDEWEQVGPR 26 0 Q14694;Q14694-3;Q14694-2;H3BNA1 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 0 NHSVNEEEQEEQGEGS(1)EDEWEQVGPR;NHSVNEEEQEEQGEGS(1)EDEWEQVGPR;NHSVNEEEQEEQGEGS(1)EDEWEQVGPR ;; 167.34 2.64E-12 163140600 3888.1 2938.46 3378.79 3494.96 3653.25 4788.1 3497.49 3760.16 4069.7 3942 TRUE FALSE FALSE 3580.352782 3192.447389 3504.01093 3480.498782 3609.68738 3794.994087 3595.620156 4906.615474 3623.264092 4078.984207 0.877755981 0.782657453 0.859040083 0.853275866 0.884947623 0.930377245 0.881498916 1.202901317 0.888276078 1 11.99399421 -4.257836641 24.83751139 0.911421623 1.202901438 0.712615149 0.058460028 181.1866977 1249053.197 0.010459057 0.103321006 5.52E-05 4.257836641 0.291479816 NHYTPVRTAKQT(ph)PGHY(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 NHYTPVRTAKQTPGHYGK 18 2 V9GZ25;Q6ZSJ9-2;Q6ZSJ9-3 V9GZ25 SHISA6 2 0 NHY(0.008)T(0.01)PVRT(0.006)AKQT(0.984)PGHY(0.991)GK 47.814 0.019687 43320000 2285.4 1856.1 2465.9 2476.7 2415.8 4037.9 3169.3 1044.7 2595.9 1866.4 TRUE FALSE FALSE 2104.508178 2016.533013 2557.288423 2466.452072 2386.993163 3200.394023 3258.222028 1363.224221 2311.136265 1931.257261 1.089708876 1.044155563 1.324157312 1.277122485 1.235978868 1.657155723 1.687098914 0.705873965 1.196700363 1 10.91532464 -6.686708089 1.333712829 1.03640482 1.361680371 0.130305528 0.261251751 0.429674893 1.540236364 0.043405629 0.067086868 2.06E-07 6.686708089 0.325275551 NIDDASQMDLFHRDS(ph)DDDQTEEQLDESEAR ddPTM_HeLa_Curcumin_4h_R1 5 NIDDASQMDLFHRDSDDDQTEEQLDESEAR 30 1 Q9HAW4-2;Q9HAW4-3;Q9HAW4;E7ESG2 Q9HAW4-2 CLSPN Claspin 1 0 NIDDAS(0.001)QMDLFHRDS(0.999)DDDQTEEQLDESEAR;NIDDAS(0.004)QMDLFHRDS(0.92)DDDQT(0.076)EEQLDESEAR;NIDDASQMDLFHRDS(1)DDDQTEEQLDESEAR;NIDDASQMDLFHRDS(1)DDDQTEEQLDESEAR;NIDDASQMDLFHRDS(1)DDDQTEEQLDESEAR ;;;; 127.25 9.99E-13 56845100 5695.47 4704.83 4943.04 4985.13 4982.31 6353.12 4468.19 2869.73 5819.94 4827.16 TRUE FALSE FALSE 5244.66754 5111.494541 5126.233411 4964.502853 4922.899207 5035.411298 4593.555386 3744.697466 5181.507143 4994.903451 1.050003787 1.023342011 1.026292793 0.993913677 0.985584457 1.008109836 0.919648484 0.749703674 1.037358819 1 12.28624108 -3.550263215 0.962665795 1.021968466 1.71E-15 0.952368696 0.018299128 1.150856085 0.306158292 0.003490887 1.703815127 0.000281668 3.550263215 -1.021968466 NIDDCPNHR ddPTM_HeLa_Curcumin_4h_R1 1 NIDDCPNHR 9 0 Q04721;D2WEZ3 Q04721 NOTCH2 Neurogenic locus notch homolog protein 2;Notch 2 extracellular truncation;Notch 2 intracellular domain 0 0 77.192 0.014962 256940 178.43 189.17 258.61 133.94 249.46 136.84 149.63 0 223.73 243.87 FALSE FALSE TRUE 164.3070772 205.5210119 268.1943141 133.3857918 246.4853524 108.4578415 153.8282151 0 199.1873787 252.3444643 0.651122178 0.814446286 1.062810372 0.528586161 0.976781294 0.429800756 0.609596155 0 0.78934713 1 7.979250629 -4.551316651 1.064299963 0.834949261 1.72E-13 0.615013556 0.188237718 0.641861487 0.786315719 0.029666086 0.535361077 2.81E-05 4.551316651 -0.834949261 NIDDGTSDRPYSHALVAGIDRYPR ddPTM_HeLa_Curcumin_4h_R1 2 NIDDGTSDRPYSHALVAGIDRYPR 24 2 P61353;K7ELC7 P61353 RPL27 60S ribosomal protein L27 0 0 ; ; 88.983 2.81E-05 122813000 5977.3 4677.3 4455.3 4971.5 4357.6 8468.5 5290.4 4866.6 6639.8 5932.4 FALSE FALSE TRUE 5504.190398 5081.58497 4620.417337 4950.92925 4305.638466 6712.03764 5438.834386 6350.403937 5911.430552 6138.550458 0.896659632 0.827815134 0.752688663 0.806530676 0.70140964 1.093423877 0.886012817 1.034511972 0.963001052 1 12.58368231 -3.526066278 1.194632903 0.906090914 1.480460593 0.105789685 0.113720884 16.46605764 5.402582046 0.018547487 18.04435416 0.000297806 3.526066278 0.574369679 NIEDVIAQGIGK ddPTM_HeLa_Curcumin_4h_R1 2 NIEDVIAQGIGK 12 0 P05387;H0YDD8 P05387 RPLP2 60S acidic ribosomal protein P2 0 0 ; ; 165.66 0.00091106 7482500 1949.06 1879.46 1734.44 1763.83 2260.4 2610.88 1863.21 2049.11 2203.9 2234.05 FALSE FALSE TRUE 1794.789844 2041.912148 1798.719872 1756.531739 2233.446206 2069.354057 1915.486658 2673.874206 1962.137684 2311.683071 0.776399614 0.883301078 0.778099686 0.759849722 0.966155886 0.895172043 0.828611275 1.156678543 0.848791821 1 11.1747279 -4.25529891 24.43055809 0.876522341 1.156678715 0.561315012 0.077500456 383.4949758 1525717.864 0.013611578 0.165761723 5.56E-05 4.25529891 0.280156374 NIEDYIHR ddPTM_HeLa_Curcumin_4h_R1 1 NIEDYIHR 8 0 Q9BUQ8 Q9BUQ8 DDX23 Probable ATP-dependent RNA helicase DDX23 0 0 134.77 0.0033751 5120500 4264.1 3229.6 3522.9 3348.6 3623.5 4491.4 3673.3 3162.9 3711 3754.1 FALSE FALSE TRUE 3926.591986 3508.752233 3653.461773 3334.74438 3580.292129 3559.833011 3776.362912 4127.25365 3303.912584 3884.554696 1.01082165 0.903257261 0.940509803 0.85846246 0.921673759 0.916406973 0.972148215 1.062477935 0.850525438 1 11.92353351 -7.276343499 23.97094239 1.005110227 0.935923478 0 0.069968371 437.0993691 703004.1132 0.008666368 0.00993495 5.29E-08 7.276343499 -0.069186749 NIGK(ac)TLVTR ddPTM_HeLa_Curcumin_4h_R1 2 NIGKTLVTR 9 1 P61247;H0Y9Y4;D6RAT0;D6RG13;D6RB09;E9PFI5;H0Y8L7;D6RAS7;D6RGE0;D6RI02;D6RED7 P61247 RPS3A 40S ribosomal protein S3a 0 1 ; NIGK(1)TLVTR;NIGK(1)TLVTR 134.23 0.00037172 20639100 4104.5 3491.2 3269.3 3094 3293.6 4273 3103.9 2504 4053.1 3315 FALSE TRUE FALSE 3779.624494 3792.963772 3390.463134 3081.197848 3254.325971 3386.731633 3190.98708 3267.458073 3608.48507 3430.196003 1.101868374 1.105757154 0.988416735 0.898257081 0.948728868 0.987328896 0.930263774 0.95255725 1.05197635 1 11.7440753 -6.548458371 7.216722808 1.053612146 0.945147354 0.726045271 0.034927711 0.099534385 19.69041034 0.007350465 0.010496558 2.83E-07 6.548458371 -0.108464791 NIGLGFK(ac)TPK ddPTM_HeLa_Curcumin_4h_R1 2 NIGLGFKTPK 10 1 P62280;M0QZC5 P62280 RPS11 40S ribosomal protein S11 0 1 ; NIGLGFK(1)TPK;NIGLGFK(1)TPK 169.93 1.82E-12 66685000 9636.9 7436.3 8040.6 8892.1 7946 10652.1 8254.8 7467.1 9521.8 8116.8 FALSE TRUE FALSE 8874.129196 8079.060636 8338.591709 8855.306846 7851.24914 8442.734386 8486.407471 9743.784416 8477.282362 8398.858196 1.056587573 0.961923686 0.992824443 1.054346512 0.934799583 1.005224066 1.01042395 1.160132031 1.00933748 1 13.0359775 -4.260540702 24.35403623 1.014105354 1.160132092 0.615383279 0.036336514 30.37717054 823023.8861 0.005405875 0.043513439 5.49E-05 4.260540702 0.146026738 NIGRDT(ph)PTSAGPNSFNK ddPTM_HeLa_Curcumin_4h_R1 2 NIGRDTPTSAGPNSFNK 17 1 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 0 NIGRDT(0.995)PT(0.005)SAGPNSFNK;NIGRDT(0.976)PT(0.022)S(0.002)AGPNSFNK ; 100.47 0.0017144 146482000 4730.3 4465.7 4656.2 4737.6 3927.5 5948.2 5609.1 3220.7 5121.9 3676.9 TRUE FALSE FALSE 4355.891764 4851.695209 4828.762868 4717.997066 3880.667128 4714.47627 5766.47625 4202.676604 4560.040384 3804.672001 1.144879706 1.275194079 1.269166663 1.240053562 1.01997416 1.239128174 1.515630322 1.104609439 1.198537057 1 11.89355637 -8.308058075 0.414784654 0.973544201 1.261743892 0.047102008 0.137268327 1.006709937 0.386397858 0.122553433 0.05226761 4.92E-09 8.308058075 0.288199691 NIGS(ph)DFIPR ddPTM_HeLa_Curcumin_4h_R1 2 NIGSDFIPR 9 0 Q5T853;Q5T857;P41279-2;P41279 Q5T853 MAP3K8 Mitogen-activated protein kinase kinase kinase 8 1 0 NIGS(1)DFIPR;NIGS(1)DFIPR ; 91.093 0.018352 10174100 4100.5 3768.8 3572.5 3803.8 3714.7 5177.6 4927.4 4581.7 4412.7 4772.6 TRUE FALSE FALSE 3775.941098 4094.558279 3704.899993 3788.060883 3670.404629 4103.707396 5065.649583 5978.639238 3928.63785 4938.447495 0.764600839 0.82911852 0.750215528 0.767055008 0.743230465 0.830971151 1.025757505 1.210631326 0.79552083 1 12.26984186 -4.494094886 2.69109147 0.850320896 1.212048207 0.709754177 0.079549813 0.196199351 2.459332525 0.015785834 0.123491954 3.21E-05 4.494094886 0.361727311 NIGVDNPAAK ddPTM_HeLa_Curcumin_4h_R1 1 NIGVDNPAAK 10 0 F5GWF6;P78371;F8VQ14;P78371-2 F5GWF6 CCT2 T-complex protein 1 subunit beta 0 0 112.71 0.0045427 5540700 4844.4 3787.1 3900.4 4083.8 4043.6 5752 4139.1 3787.8 4572.5 3881.2 FALSE FALSE TRUE 4460.960628 4114.440049 4044.952255 4066.902318 3995.382711 4558.970362 4255.232006 4942.682783 4070.90819 4016.071411 1.110777218 1.024493747 1.007191317 1.012656873 0.994848523 1.135181598 1.059550882 1.230725821 1.013654334 1 11.97156921 S(ph)ESPVCSSR ddPTM_HeLa_Curcumin_4h_R1 1 SESPVCSSR 9 0 O00472;D6RC27 O00472 ELL2 RNA polymerase II elongation factor ELL2 1 0 S(0.5)ES(0.5)PVCSSR 133.75 0.0033291 54871000 3698.8 3601.7 3366.7 3344.6 3545 3906.4 2290.7 794.98 4389.5 3710.7 TRUE FALSE FALSE 3406.036077 3913.014899 3491.472864 3330.760931 3502.72819 3096.168606 2354.970877 1037.365742 3907.982832 3839.646549 0.887070212 1.0191081 0.909321423 0.867465505 0.912252767 0.80636813 0.61333012 0.270172197 1.017797545 1 11.9067578 -4.318307134 1.091565162 0.944288074 1.05E-18 0.950526694 0.048657858 0.249942573 0.25155988 0.007868359 0.264835446 4.80E-05 4.318307134 -0.944288074 down NIIEATHMYDNAAEACSTTEEVFNS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 NIIEATHMYDNAAEACSTTEEVFNSPR 27 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 0 NIIEATHMYDNAAEACS(0.001)T(0.005)T(0.005)EEVFNS(0.99)PR 136 2.38E-08 10550000 1354.9 1008.8 1120.1 1097.3 1015.7 1143.4 922.88 480.01 1107.3 1244.3 TRUE FALSE FALSE 1247.658235 1095.996177 1161.611891 1092.759663 1003.588441 906.2459512 948.773529 626.3628393 985.8319603 1287.539332 0.969025337 0.851233162 0.902195267 0.848719442 0.779462356 0.703858848 0.736888967 0.486480547 0.765671336 1 10.33040079 -3.68387947 0.30603488 1.007439472 9.98E-21 0.626001513 0.08582333 1.81978662 0.094401225 0.01684215 0.729811791 0.000207072 3.68387947 -1.007439472 NIIFFVRPR ddPTM_HeLa_Curcumin_4h_R1 2 NIIFFVRPR 9 1 F5H6Y0;H3BMM5;A0A2R8YF87;Q96AX1 F5H6Y0 VPS33A Vacuolar protein sorting-associated protein 33A 0 0 ; ; 109.11 0.0018731 1464320 330.84 140.5 105.01 247.7 310.53 444.43 179.581 156.08 387.32 312.96 FALSE FALSE TRUE 304.6536649 152.6441939 108.901763 246.675083 306.8271326 352.2502082 184.6195595 203.6680735 344.831965 323.8353367 0.940767206 0.471363612 0.33628746 0.761729975 0.94747885 1.087744814 0.570103193 0.628924797 1.06483736 1 8.33911661 -7.427086517 8.878058035 0.973977615 0.696724243 0.325016869 0.207433471 0.371756496 31.86337137 0.038154656 0.043537665 3.74E-08 7.427086517 -0.277253373 S(ph)AEPS(ph)PTVMSTSLGSNLSELDR ddPTM_HeLa_Curcumin_4h_R1 2 SAEPSPTVMSTSLGSNLSELDR 22 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-3;A0A1B0GU60;F5H836 A0A1B0GTU4 PXN Paxillin 2 0 S(0.992)AEPS(0.885)PT(0.123)VMSTSLGSNLSELDR;S(0.959)AEPS(0.937)PT(0.085)VMS(0.015)T(0.003)SLGSNLSELDR ; 106.51 8.65E-05 6000100 1970.71 1975.35 1980.98 1929 1808.44 2602.6 2067 3910.9 2093.86 1686.27 TRUE FALSE FALSE 1814.726224 2146.090452 2054.396861 1921.018309 1786.875534 2062.791423 2124.994457 5103.315406 1864.168797 1744.867757 1.04003654 1.229944472 1.177394019 1.100953526 1.024075049 1.182205021 1.21785416 2.924757699 1.068372539 1 10.76890198 -4.249583081 3.585603738 1.062962586 3.164304856 0.978837027 0.079776411 0.034168046 0.765228105 0.013336585 0.194902074 5.63E-05 4.249583081 2.101342271 up NIIHGS(ph)DSVESAEK ddPTM_HeLa_Curcumin_4h_R1 3 NIIHGSDSVESAEK 14 0 P15531;P15531-2 P15531 NME1 Nucleoside diphosphate kinase A 1 0 NIIHGS(0.993)DS(0.007)VESAEK;NIIHGS(0.794)DS(0.186)VES(0.021)AEK;NIIHGS(0.913)DS(0.087)VESAEK ;; 199.61 7.23E-07 48468000 14817.2 12630.2 15832.4 11193.9 16396.8 33394.1 21036.2 9049.8 13939.4 12388.8 TRUE FALSE FALSE 13644.40298 13721.89821 16419.16267 11147.58261 16201.27887 26467.78723 21626.41916 11809.04236 12410.28269 12819.30988 1.064363302 1.070408496 1.280814867 0.869593037 1.263818335 2.064681132 1.687018986 0.921191739 0.968092886 1 13.64603098 -5.515884055 24.37206698 1.046112439 1.586182867 0.406052784 0.278697478 150.4487792 524217.4664 0.037747398 0.077997621 3.05E-06 5.515884055 0.540070428 NIIHGS(ph)DSVK ddPTM_HeLa_Curcumin_4h_R1 2 NIIHGSDSVK 10 0 Q32Q12;P22392-2;P22392;O60361 Q32Q12 NME1-NME2;NME2;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase 1 0 NIIHGS(0.997)DS(0.003)VK;NIIHGS(0.649)DS(0.351)VK ; 130.2 0.0028916 34097800 6246.2 4705.1 5368.2 4849.3 5311.98 10237.4 6577 2763.31 6260.9 4995.6 TRUE FALSE FALSE 5751.806679 5111.787878 5567.150214 4829.234881 5248.638108 8114.047841 6761.532919 3605.830498 5574.094934 5169.196728 1.112708024 0.988894048 1.076985556 0.934233138 1.015368225 1.569692211 1.308043256 0.697561089 1.078329038 1 12.33572439 NIIHGSDS(ph)VK ddPTM_HeLa_Curcumin_4h_R1 2 NIIHGSDSVK 10 0 Q32Q12;P22392-2;P22392;O60361 Q32Q12 NME1-NME2;NME2;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase 1 0 NIIHGS(0.089)DS(0.911)VK;NIIHGS(0.079)DS(0.921)VK ; 96.371 0.0070804 12671000 8760.2 7567.1 7052.8 6242.1 11269.5 24987 11756.8 5132 10453 7669.4 TRUE FALSE FALSE 8066.820926 8221.166406 7314.182972 6216.271844 11135.11857 19804.41454 12086.66417 6696.723175 9306.332052 7935.911079 1.016495881 1.035944874 0.921656367 0.78330916 1.403130461 2.495543907 1.523034223 0.843850581 1.172686029 1 12.95418015 -5.553456315 7.694682212 0.992363721 1.666484229 0.361250209 0.383250096 0.144028321 29.37961858 0.053207598 0.107532602 2.80E-06 5.553456315 0.674120508 NIILEEGK ddPTM_HeLa_Curcumin_4h_R1 1 NIILEEGK 8 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 0 111.95 0.0054204 8481400 8863.8 6807.8 8130.7 8101.6 9348.6 8263.8 7989.2 7082.5 7417.8 6973.2 FALSE FALSE TRUE 8162.220877 7396.235897 8432.030894 8068.077726 9237.124051 6549.794728 8213.35545 9241.921646 6604.085898 7215.518181 1.131203702 1.025045702 1.168596722 1.118156385 1.280174732 0.907737263 1.138290452 1.280839631 0.915261487 1 12.81688729 -13.52287875 0.185779626 0.428428644 1.158177382 0.301291754 0.105478283 66.43759878 0.776164715 13.73457957 0.124764094 3.00E-14 13.52287875 0.729748738 NIIS(ph)PPWDFR ddPTM_HeLa_Curcumin_4h_R1 2 NIISPPWDFR 10 0 Q5T8C6;Q13042-4;Q13042-3;Q13042-2;Q13042 Q5T8C6 CDC16 Cell division cycle protein 16 homolog 1 0 NIIS(1)PPWDFR;NIIS(1)PPWDFR ; 103.43 0.010434 17941900 4777.2 3843.1 4127.7 4316.4 4530 5080.3 4397.8 4433.8 4167.7 4384.2 TRUE FALSE FALSE 4399.079579 4175.280439 4280.676193 4298.53988 4475.982709 4026.588513 4521.190432 5785.645209 3710.513737 4536.550624 0.969697011 0.920364565 0.94359714 0.947534865 0.986648906 0.887588136 0.996614125 1.275340162 0.817915206 1 12.14738004 -4.268311079 4.586517816 0.969014057 1.293082899 0.733239832 0.05854799 0.047989677 2.632651607 0.005180527 0.049401262 5.39E-05 4.268311079 0.324068841 NILFVITKPDVYK ddPTM_HeLa_Curcumin_4h_R1 1 NILFVITKPDVYK 13 1 F8VZJ2;F8W0W4;H0YHX9;Q13765;E9PAV3-2;E9PAV3;F8W1N5;F8VNW4;F8VZ58;Q9BZK3 F8VZJ2 NACA;NACAP1 "Nascent polypeptide-associated complex subunit alpha;Nascent polypeptide-associated complex subunit alpha, muscle-specific form;Putative nascent polypeptide-associated complex subunit alpha-like protein" 0 0 126.1 0.00066565 2936000 1008.6 809.78 896.06 839.48 865.29 1342.6 881.25 900.33 877.82 711.22 FALSE FALSE TRUE 928.7682457 879.7737749 929.2687719 836.0064542 854.9719819 1064.129626 905.9755032 1174.836472 781.5253422 735.9348421 1.262025104 1.195450636 1.262705227 1.135978902 1.161749564 1.445956306 1.231053962 1.596386535 1.061949099 1 9.523434229 -1 0.032087686 9.33E-13 3.124479561 0.570331384 0.109394735 593.7172725 1.474053256 44.68585993 113.9972578 0.1 1 3.124479561 NILSGLNASFPLHNNTGS(ph)STVTTS(ph)KS(ph)IK ddPTM_HeLa_Curcumin_4h_R1 1 NILSGLNASFPLHNNTGSSTVTTSKSIK 28 1 A0A1W2PS94;A0A2R8Y358;Q9BXT5 A0A1W2PS94 TEX15 Testis-expressed sequence 15 protein 3 0 NILS(0.003)GLNAS(0.003)FPLHNNT(0.387)GS(0.441)S(0.197)T(0.197)VT(0.196)T(0.276)S(0.65)KS(0.65)IK 43.162 0.0083289 0 431 303.09 274.94 387.77 287.44 427.84 246.67 439.73 383.95 284.17 TRUE FALSE FALSE 396.8858952 329.2877491 285.1295183 386.1655105 284.0124657 339.1011612 253.5908963 573.8016527 341.8316456 294.0448863 1.349745953 1.119855384 0.969680248 1.313287625 0.965881329 1.153229241 0.862422399 1.951408371 1.162515185 1 8.199892591 -1.000000392 0.017405739 2.20E-08 2.685987638 0.070987657 0.284197049 10482.60362 14.2196626 848.8888733 1413.449262 0.09999991 1.000000392 2.685987616 NILVFGEDGSGK ddPTM_HeLa_Curcumin_4h_R1 1 NILVFGEDGSGK 12 0 O43237;O43237-2;H3BUM4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 0 0 117.14 2.54E-06 0 0 77.306 0 177.99 216.03 177.14 66.386 129.74 72.839 242.29 FALSE FALSE TRUE 0 83.98798617 0 177.2535245 213.4539833 140.3991672 68.24861249 169.2971288 64.84874393 250.7095595 0 0.335001132 0 0.707007443 0.851399459 0.560007235 0.27222182 0.675271933 0.258660835 1 7.969873196 -9.589072348 1.403182675 0.997411668 0.372028097 0 0.355324921 0.369733761 1.314351158 0.214478318 0.05074591 2.58E-10 9.589072348 -0.625383572 NINMDNDLEVLTS(ph)SPTR ddPTM_HeLa_Curcumin_4h_R1 1 NINMDNDLEVLTSSPTR 17 0 Q9Y5T5-2;Q9Y5T5;Q9Y5T5-4;Q9Y5T5-3 Q9Y5T5-2 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 0 NINMDNDLEVLT(0.131)S(0.363)S(0.363)PT(0.143)R 72.676 0.019361 20315000 3244.4 2684.6 2652.9 3017.3 3030.1 4278.9 3367.6 3014 3310.1 2668 TRUE FALSE FALSE 2987.602317 2916.644862 2751.218808 3004.815212 2993.968037 3391.407907 3462.085793 3932.954725 2946.990311 2760.712801 1.082185121 1.056482536 0.996561035 1.088420067 1.084490946 1.228453719 1.254055036 1.424615673 1.067474425 1 11.4308251 -4.135315347 0.642388443 1.035046763 1.725519141 0.929308365 0.033836466 0.703755524 0.17841892 0.006754323 0.369058646 7.32E-05 4.135315347 0.690472378 NINMDNDLEVLTSS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 5 NINMDNDLEVLTSSPTR 17 0 Q9Y5T5-2;Q9Y5T5;Q9Y5T5-4;Q9Y5T5-3 Q9Y5T5-2 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 0 NINMDNDLEVLT(0.001)S(0.049)S(0.805)PT(0.146)R;NINMDNDLEVLTS(0.232)S(0.767)PTR;NINMDNDLEVLT(0.033)S(0.344)S(0.47)PT(0.153)R;NINMDNDLEVLT(0.006)S(0.233)S(0.679)PT(0.083)R;NINMDNDLEVLT(0.002)S(0.282)S(0.716)PTR ;;;; 183.71 5.57E-06 255659000 18620.6 13847 16057.7 16787.9 16607.2 19381.6 16729.2 14709.5 19373.2 16289.7 TRUE FALSE FALSE 17146.75986 15043.87298 16652.81249 16718.43612 16409.16999 15361.63768 17198.57633 19194.35884 17248.00843 16855.76586 1.017263766 0.892506048 0.987959409 0.991852655 0.97350486 0.911358037 1.020337875 1.138741425 1.023270528 1 14.04095456 -4.302621167 3.911840437 0.989205026 1.147364451 0.55902564 0.042334161 0.133001176 3.862347975 0.006075692 0.054750427 4.98E-05 4.302621167 0.158159425 NINPSTANS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 NINPSTANSPK 11 0 P46937-6;P46937-7;P46937;P46937-9;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 0 NINPS(0.116)T(0.394)ANS(0.49)PK;NINPS(0.016)T(0.171)ANS(0.813)PK ; 163.62 0.00028474 44980000 9546.8 8836.1 8821.9 9787.7 9124.1 12078.4 10263.8 3821 10087.5 6969.4 TRUE FALSE FALSE 8791.160706 9599.853111 9148.847375 9747.201091 9015.301067 9573.203688 10551.7746 4986.00531 8980.926488 7211.586131 1.219032893 1.331170832 1.268631783 1.35160295 1.250113484 1.32747547 1.46316974 0.691388166 1.245346908 1 12.81610089 -8.752684941 0.781398656 1.007411145 1.256749906 0 0.208937218 0.732733142 0.875349365 0.098680855 0.038694564 1.77E-09 8.752684941 0.249338761 NINTFVET(ph)PVQK ddPTM_HeLa_Curcumin_4h_R1 1 NINTFVETPVQK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 NINTFVET(1)PVQK 185.32 0.00012181 13326000 1325.9 1340.7 1720 1603 2235.3 3868.5 3910 870.16 1853.3 1100.2 TRUE FALSE FALSE 1220.953616 1456.584134 1783.744713 1596.367211 2208.645507 3066.129493 4019.704077 1135.467778 1649.997627 1138.431868 1.072487208 1.279465355 1.566843623 1.402250987 1.940077021 2.693292044 3.53091317 0.99739634 1.449360013 1 10.15283224 -5.831546789 1.309816323 1.071038362 2.509480239 0.37674061 0.617580168 0.249302512 0.853351742 0.09003554 0.225327588 1.47E-06 5.831546789 1.438441877 TGLS(ph)AGVTGT(ph)T(ph)GPSAEAT(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 TGLSAGVTGTTGPSAEATGK 20 0 Q7Z5P9-2;Q7Z5P9 Q7Z5P9-2 MUC19 Mucin-19 4 0 T(0.364)GLS(0.642)AGVT(0.415)GT(0.789)T(0.789)GPS(0.046)AEAT(0.955)GK 65.374 0.0046704 5479100 1029.4 875.47 927.75 894.7 808.17 891.43 553.31 303.88 1028.9 1015.2 TRUE FALSE FALSE 947.9219038 951.1417258 962.1332311 890.9979685 798.5331006 706.5373695 568.8343894 396.5316131 916.0322442 1050.478124 0.902371865 0.905436966 0.915900302 0.848183268 0.76016157 0.672586466 0.541500462 0.377477269 0.872014584 1 10.0368304 -4.317237979 0.488515974 0.962710024 3.62E-18 0.963654459 0.035232206 0.425929982 0.070351125 0.006810571 0.232490302 4.82E-05 4.317237979 -0.962710024 down NIPSPGQLDPDT(ph)RIPVINLEDGTR ddPTM_HeLa_Curcumin_4h_R1 2 NIPSPGQLDPDTRIPVINLEDGTR 24 1 Q9P2D1 Q9P2D1 CHD7 Chromodomain-helicase-DNA-binding protein 7 1 0 NIPS(0.004)PGQLDPDT(0.994)RIPVINLEDGT(0.002)R;NIPS(0.135)PGQLDPDT(0.863)RIPVINLEDGT(0.002)R ; 68.406 0.00095917 39053000 3548.6 2644.9 3245.4 3127.8 2834.2 3347 2874.5 1373.25 3824.4 3232.6 TRUE FALSE FALSE 3267.724566 2873.513371 3365.677379 3114.857992 2800.404016 2652.794472 2955.150734 1791.947603 3404.872888 3344.932609 0.976917908 0.859064653 1.00620185 0.931216965 0.837207903 0.7930786 0.883470933 0.535720091 1.017919727 1 11.70776143 -3.423241917 0.443658682 0.987726258 5.10E-18 0.749316305 0.068935199 3.175106697 0.245027417 0.014397215 1.943582639 0.000377362 3.423241917 -0.987726258 NISFNDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 NISFNDKK 8 1 P26038;P35241-4;E7EQR4;P15311 P26038;E7EQR4 MSN;EZR Moesin;Ezrin 0 1 ; NISFNDK(1)K;NISFNDK(1)K 110.14 0.0021658 41521000 7596.8 8901.8 6197.5 6888.6 11430.3 20934.4 14413.7 13938.6 17317.1 7850.3 FALSE TRUE FALSE 6995.505264 9671.231926 6427.184802 6860.096798 11294.00114 16592.36946 14818.10963 18188.41497 15417.45746 8123.097341 0.86118693 1.190584271 0.791223413 0.84451737 1.390356494 2.042616106 1.824194517 2.239098488 1.897977681 1 12.98781422 -5.451263117 2.696821553 0.936978673 2.024194963 0.585097439 0.33579675 0.05058912 0.718146025 0.020209972 0.04942602 3.54E-06 5.451263117 1.08721629 NISS(ph)SPSVESLPGGR ddPTM_HeLa_Curcumin_4h_R1 2 NISSSPSVESLPGGR 15 0 Q92609;Q92609-2;C9J3F6 Q92609 TBC1D5 TBC1 domain family member 5 1 0 NISS(0.343)S(0.343)PS(0.157)VES(0.157)LPGGR;NIS(0.004)S(0.79)S(0.088)PS(0.088)VES(0.03)LPGGR ; 130.47 0.00071384 65213400 8825 8218.21 8152 8510.63 8413.46 11475.7 8561.37 6958.12 10184.05 6822.86 TRUE FALSE FALSE 8126.491938 8928.555453 8454.120291 8475.415268 8313.134985 9095.510462 8801.579 9079.618757 9066.885194 7059.953877 1.151068701 1.264676173 1.197475286 1.200491592 1.177505566 1.288324346 1.246690723 1.286073382 1.284269749 1 12.78544304 -8.79482074 0.257341341 0.896304749 1.286121066 0 0.096831494 0.961340614 0.117611538 0.126103209 0.03636761 1.60E-09 8.79482074 0.389816317 NITLDDASAPR ddPTM_HeLa_Curcumin_4h_R1 1 NITLDDASAPR 11 0 O75534-2;O75534;O75534-3;O75534-4;E9PLT0 O75534-2 CSDE1 Cold shock domain-containing protein E1 0 0 125.23 0.0014205 2695100 1136.4 971.91 891.11 1097.1 1206.1 1218.7 1078.7 836.53 997.13 1277 FALSE FALSE TRUE 1046.452741 1055.91757 924.1353205 1092.560491 1191.718045 965.9278824 1108.965419 1091.584146 887.7473337 1321.375655 0.791941896 0.799104755 0.699373654 0.826835644 0.901876798 0.731001724 0.839250681 0.826096759 0.671835697 1 10.36782495 -9.143191436 0.80311974 1.005900575 0.800975943 0 0.114367995 0.325859787 0.364181303 0.041434018 0.01076737 7.19E-10 9.143191436 -0.204924633 LNRSDS(ph)DSSTLAK ddPTM_HeLa_Curcumin_4h_R1 1 LNRSDSDSSTLAK 13 1 Q6AWC2-7;Q6AWC2-3;Q6AWC2-2;Q6AWC2-4;Q6AWC2;Q6AWC2-6 Q6AWC2-7 WWC2 Protein WWC2 1 0 LNRS(0.022)DS(0.458)DS(0.458)S(0.051)T(0.01)LAK 164.93 0.0016875 11342000 4659.1 3605.7 3407.1 4226.7 3390.6 3928.6 2297.2 1289.3 4448.2 4141.2 TRUE FALSE FALSE 4290.327319 3917.360641 3533.370123 4209.211035 3350.169309 3113.764076 2361.653249 1682.401635 3960.243589 4285.106392 1.001218389 0.914180485 0.824569987 0.982288571 0.781817067 0.72664802 0.551130598 0.392616071 0.924187926 1 12.06511531 -4.316536187 0.518043917 0.999288098 1.65E-24 0.914339981 0.056708219 0.611610315 0.113797708 0.010347656 0.36517094 4.82E-05 4.316536187 -0.999288098 down NITVIFHPLLR ddPTM_HeLa_Curcumin_4h_R1 2 NITVIFHPLLR 11 0 Q96A65 Q96A65 EXOC4 Exocyst complex component 4 0 0 ; ; 74.76 0.017933 1361930 670.66 459.98 635.58 456.85 527.03 766.43 683.58 622.3 502.79 671.6 FALSE FALSE TRUE 617.5765533 499.7386216 659.1351539 454.9596757 520.7455115 607.4637786 702.759415 812.0364053 447.6351949 694.93805 0.888678571 0.719112476 0.948480449 0.654676594 0.749340911 0.874126519 1.011254766 1.168501862 0.644136833 1 9.440740565 -4.448817294 2.719584663 0.891431326 1.17479464 0.314165315 0.135323976 0.310940759 3.793381997 0.018187568 0.160159859 3.56E-05 4.448817294 0.283363315 NIVEAAAVR ddPTM_HeLa_Curcumin_4h_R1 1 NIVEAAAVR 9 0 Q5JNZ5;P62854 Q5JNZ5 RPS26P11;RPS26 Putative 40S ribosomal protein S26-like 1;40S ribosomal protein S26 0 0 94.309 0.015889 4667800 2978.8 2311.2 2744.5 2524.9 2774.7 3652.7 2742.2 2624 2921.1 2363.4 FALSE FALSE TRUE 2743.024837 2510.969829 2846.213584 2514.452633 2741.613515 2895.088846 2819.138752 3424.045521 2600.662638 2445.527974 1.121649339 1.026759807 1.163844215 1.028183958 1.121072236 1.183829781 1.152773054 1.400125272 1.063436062 1 11.25593025 -1 0.521126476 1.057922834 12.64851609 0.770291434 0.052477835 39.75884009 0.360852088 0.011102585 512.3416788 0.1 1 11.59059326 NIYS(ph)EELR ddPTM_HeLa_Curcumin_4h_R1 2 NIYSEELR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 NIYS(1)EELR;NIYS(1)EELR ; 114.89 0.0098656 49019000 6842.2 5416.8 5660.1 5874.5 6233.9 6559.4 5988.9 5493.9 6255.4 5652.2 TRUE FALSE FALSE 6300.63265 5885.004055 5869.868285 5850.192876 6159.564814 5198.9065 6156.932416 7168.964819 5569.19827 5848.613529 1.077286543 1.006222077 1.003634153 1.000270038 1.053166666 0.888912641 1.052716577 1.22575458 0.952225385 1 12.51387895 -4.284514779 4.474285616 1.021961358 1.235868855 0.597378641 0.053258144 0.096527178 4.606195386 0.007170785 0.061519604 5.19E-05 4.284514779 0.213907498 NIYSEELR ddPTM_HeLa_Curcumin_4h_R1 2 NIYSEELR 8 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 103.56 0.010159 26799000 5748.9 4778.2 4731.4 5436.5 5527.7 6402 4982.2 4778.3 5811.9 4976.3 FALSE FALSE TRUE 5293.868499 5191.206317 4906.749846 5414.005203 5461.785788 5074.153035 5121.987123 6235.181673 5174.349111 5149.226055 1.028090133 1.008152732 0.952910164 1.051421155 1.060700332 0.985420524 0.994710092 1.210896862 1.004878997 1 12.33013989 -4.258397734 24.99631438 1.012069537 1.210896935 0.803710478 0.029823205 92.50411093 760162.0681 0.004089418 0.038546267 5.52E-05 4.258397734 0.198827398 NDSGEENVPLDLT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 NDSGEENVPLDLTR 14 0 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 0 NDS(0.009)GEENVPLDLT(0.991)R 149.94 0.0014901 48018000 3079.9 3116.7 2995.6 3082.8 3901.9 3698.9 2497 1093.7 3001 3126.9 TRUE FALSE FALSE 2836.122665 3386.09366 3106.619571 3070.04419 3855.372391 2931.706445 2567.0591 1427.164095 2671.797808 3235.559542 0.876547821 1.04652491 0.960149097 0.948844906 1.191562801 0.906089474 0.793389541 0.441087261 0.825760668 1 11.65979951 -4.314667565 1.97865558 0.966167458 0.32269818 0.746616313 0.094244597 0.240997736 1.085028106 0.012823056 0.26916415 4.85E-05 4.314667565 -0.643469279 down ANS(ph)TSDSVFTETPSPVLK ddPTM_HeLa_Curcumin_4h_R1 1 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 0 ANS(0.727)T(0.203)S(0.057)DS(0.01)VFT(0.003)ETPSPVLK 166.3 1.60E-05 13072000 3273.7 1951 2646.3 3458.8 2394.5 3476.8 3820.1 7335.3 3209.4 2629.5 TRUE FALSE FALSE 3014.583191 2119.635747 2744.374206 3444.488402 2365.947151 2755.672488 3927.281725 9571.799202 2857.33685 2720.874929 1.107946256 0.779027262 1.008636662 1.265948819 0.869553806 1.012789106 1.443389287 3.517912235 1.050153691 1 11.40985493 -4.249401081 2.765515496 1.030882247 4.028305516 0.972924358 0.124816462 0.04989308 0.500899124 0.017326316 0.342842528 5.63E-05 4.249401081 2.997423269 up NKDGETPGQILGWGPPWDS(ph)AEEEEEDDASKER ddPTM_HeLa_Curcumin_4h_R1 1 NKDGETPGQILGWGPPWDSAEEEEEDDASKER 32 2 A0A140TA04;Q5STV6;A0A0A0MRT5;Q9UBC1-2;Q9UBC1-3;Q9UBC1 A0A140TA04 NFKBIL1 NF-kappa-B inhibitor-like protein 1 1 0 NKDGET(0.001)PGQILGWGPPWDS(0.958)AEEEEEDDAS(0.041)KER 45.791 0.0061439 8972200 1154.1 1059.8 996.62 965.77 971.52 1311.5 987.7 502.92 1273.2 1279.6 TRUE FALSE FALSE 1062.751767 1151.40439 1033.555614 961.7738996 959.9352585 1039.480116 1015.412204 656.2579928 1133.533145 1324.066005 0.80264259 0.869597426 0.780592214 0.72637912 0.724990488 0.78506669 0.766889415 0.495638428 0.85610018 1 10.37075933 -9.764035838 0.047613126 1.895777877 1.69E-11 0.57960742 0.079326479 67.09999039 0.657253866 16.75451202 9.975126485 1.72E-10 9.764035838 -1.895777877 NKDQGTYEDYVEGLR ddPTM_HeLa_Curcumin_4h_R1 2 NKDQGTYEDYVEGLR 15 1 P60660-2;F8W1R7;G8JLA2;G3V1V0;P60660;G3V1Y7;J3KND3;B7Z6Z4;F8VZU9;F8VPF3;F8W180 P60660-2 MYL6 Myosin light polypeptide 6 0 0 ; ; 122.33 0.00099013 145667800 5598.4 4332.9 5005.8 5135.3 5214.5 6871.8 4694.5 4868.5 6054.6 5089 FALSE FALSE TRUE 5155.280733 4707.416569 5191.319352 5114.051489 5152.320493 5446.511219 4826.215035 6352.883238 5390.425528 5265.842371 0.979003998 0.893953187 0.985847845 0.971174435 0.978441839 1.034309581 0.916513389 1.206432474 1.023658733 1 12.36244862 -4.251304625 24.92383076 0.980441995 1.206432603 0.738880371 0.041036915 496.528923 1221060.77 0.005131072 0.094513696 5.61E-05 4.251304625 0.225990608 NKDSGSDTASAIIPS(ph)TTPSVDSDDESVVK ddPTM_HeLa_Curcumin_4h_R1 1 NKDSGSDTASAIIPSTTPSVDSDDESVVK 29 1 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 1 0 NKDSGSDTASAIIPS(0.492)T(0.492)T(0.015)PSVDSDDESVVK 157.68 1.55E-13 45976000 4979.3 3588.9 4129.5 4501.4 4899.8 4925.5 3580.3 2237.7 3932.6 3909.2 TRUE FALSE FALSE 4585.183151 3899.108524 4282.542903 4482.7744 4841.373085 3903.895778 3680.753582 2919.964429 3501.203619 4045.044409 1.133530979 0.963922303 1.058713445 1.10821389 1.196865249 0.96510579 0.909941452 0.721862144 0.865553815 1 11.98193983 -4.490751304 1.689131963 1.066912526 0.687335774 0.52395872 0.091852002 0.272002902 1.042265887 0.01076526 0.144009409 3.23E-05 4.490751304 -0.379576752 NKDSGSDTASAIIPSTTPSVDS(ph)DDESVVK ddPTM_HeLa_Curcumin_4h_R1 1 NKDSGSDTASAIIPSTTPSVDSDDESVVK 29 1 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 1 0 NKDSGSDTASAIIPS(0.144)T(0.144)T(0.022)PS(0.147)VDS(0.418)DDES(0.125)VVK 70.986 8.38E-05 43831000 2800.2 1900.4 2169.8 2878.7 3075.7 3035.6 2510.2 1553.5 2928 2410.5 TRUE FALSE FALSE 2578.561215 2064.662108 2250.214697 2866.788702 3039.024286 2405.982342 2580.629456 2027.154999 2606.805725 2494.264696 1.03379614 0.827763834 0.902155533 1.149352235 1.218404884 0.96460586 1.034625339 0.812726493 1.045119923 1 11.28439886 -4.258128222 24.06182408 1.016022267 0.812726366 0.255993627 0.105617942 213.8328955 1553769.233 0.014745199 0.141358851 5.52E-05 4.258128222 -0.203295901 NKDSGSDTASAIIPSTTPSVDS(ph)DDESVVKDK ddPTM_HeLa_Curcumin_4h_R1 1 NKDSGSDTASAIIPSTTPSVDSDDESVVKDK 31 2 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 1 0 NKDSGSDTASAIIPS(0.029)T(0.029)T(0.029)PS(0.029)VDS(0.834)DDES(0.051)VVKDK 95.36 1.18E-08 22081000 7152.9 5019.9 5590.7 6405.4 5219.9 7251 4858.6 3155.3 8743.9 5668.5 TRUE FALSE FALSE 6586.740417 5453.797788 5797.89626 6378.896152 5157.656102 5747.060864 4994.91924 4117.336445 7784.716046 5865.479953 1.122966998 0.929812706 0.988477722 1.087531831 0.879323797 0.979810844 0.851578947 0.701960705 1.327208704 1 12.51803345 -3.373255734 0.529959258 1.049100351 3.75E-22 0.541121759 0.109020025 3.713783707 0.355924671 0.013765341 2.988425642 0.000423394 3.373255734 -1.049100351 NKDSGSDTASAIIPSTTPSVDS(ph)DDESVVKDKK ddPTM_HeLa_Curcumin_4h_R1 1 NKDSGSDTASAIIPSTTPSVDSDDESVVKDKK 32 3 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 1 0 NKDSGSDTASAIIPS(0.046)T(0.046)T(0.046)PS(0.173)VDS(0.67)DDES(0.019)VVKDKK 84.905 3.38E-07 18784000 4434.1 2595.3 2513.9 3282.3 2449.8 3647.2 2026.1 1580 4540.1 3241.8 TRUE FALSE FALSE 4083.136306 2819.626168 2607.067345 3268.718712 2420.587735 2890.729608 2082.946913 2061.734727 4042.062389 3354.452309 1.217228904 0.840562306 0.777196128 0.97444185 0.721604456 0.861759042 0.620949926 0.614626334 1.204984306 1 11.71186152 -6.274883583 0.709540522 1.09740234 0.669659815 0.645900275 0.121605871 0.361635885 0.355852061 0.029039194 0.07193294 5.31E-07 6.274883583 -0.427742525 NKEEAAEYAK ddPTM_HeLa_Curcumin_4h_R1 3 NKEEAAEYAK 10 1 P62753;A2A3R5 P62753 RPS6 40S ribosomal protein S6 0 0 ;; ;; 106.67 0.0045993 42544000 13632.9 12272.6 13237.3 12813.4 12414.9 15209.4 11171.4 10833.4 13130.3 12928.1 FALSE FALSE TRUE 12553.84158 13333.38886 13727.88598 12760.38155 12266.86043 12054.79899 11484.83942 14136.45379 11689.93894 13377.35051 0.938440057 0.996713725 1.026203654 0.953879584 0.916987292 0.901135018 0.858528705 1.056745413 0.873860555 1 13.70750479 -5.981469769 6.863117766 0.9768912 0.926640139 0.046864711 0.061454637 0.222566852 44.41991784 0.007699574 0.013825132 1.04E-06 5.981469769 -0.05025106 NKELYEINPPEIS(ph)EEIIGSPIPEPR ddPTM_HeLa_Curcumin_4h_R1 1 NKELYEINPPEISEEIIGSPIPEPR 25 1 Q86YS7;Q86YS7-5;Q86YS7-3;Q86YS7-2;Q86YS7-4 Q86YS7;Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 0 NKELYEINPPEIS(0.756)EEIIGS(0.244)PIPEPR 77.276 0.00011179 11513000 932.62 515.95 613.54 664.13 667.55 997.72 776.02 454.23 601.01 729.32 TRUE FALSE FALSE 858.8021429 560.546419 636.2783321 661.382006 659.5899022 790.7816254 797.7930326 592.722636 535.0807067 754.6638157 1.137993004 0.742776329 0.843128184 0.876392895 0.87401819 1.047859469 1.057150238 0.78541282 0.709031883 1 9.559690292 -7.280693418 24.99329458 1.065163363 0.899183195 0 0.150046641 685.5610371 889911.2009 0.018602455 0.021290071 5.24E-08 7.280693418 -0.165980168 NKELYEINPPEISEEIIGS(ph)PIPEPR ddPTM_HeLa_Curcumin_4h_R1 1 NKELYEINPPEISEEIIGSPIPEPR 25 1 Q86YS7;Q86YS7-5;Q86YS7-3;Q86YS7-2;Q86YS7-4 Q86YS7;Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 0 NKELYEINPPEIS(0.021)EEIIGS(0.979)PIPEPR 124.71 1.81E-08 14783000 881.51 760.09 705.04 823.56 676.29 858.93 680.76 505.4 922.91 891.73 TRUE FALSE FALSE 811.7375533 825.7887927 731.1694026 820.1523269 668.2256834 680.7782359 699.8602934 659.4941334 821.669082 922.7175511 0.879724844 0.894952948 0.792408686 0.888844399 0.7241931 0.737796994 0.758477275 0.714730236 0.89048819 1 9.849745288 -5.721166344 0.137091347 1.107415899 0.482541083 0.693273157 0.050209854 3.567470209 0.155714981 0.200722744 0.520372748 1.90E-06 5.721166344 -0.624874816 NKESS(ph)LLVSELEDTTEK ddPTM_HeLa_Curcumin_4h_R1 1 NKESSLLVSELEDTTEK 17 1 Q15058 Q15058 KIF14 Kinesin-like protein KIF14 1 0 NKES(0.434)S(0.566)LLVSELEDTTEK 65.454 0.010979 3725200 1857.1 1544.3 1800.2 1611.4 1924.5 2042 963.27 547.02 1929.9 1346 TRUE FALSE FALSE 1710.108575 1677.782411 1866.916996 1604.732454 1901.551594 1618.466182 990.2967637 713.8038798 1718.194798 1392.7734 1.227844081 1.204634157 1.340431255 1.152184881 1.365298615 1.162045586 0.711025041 0.512505394 1.233649924 1 10.44374484 -4.66381778 3.530384003 1.158557627 0.550838534 0.828874236 0.108312389 0.086724819 2.025635611 0.018961903 0.084901623 2.17E-05 4.66381778 -0.607719094 NKGS(ph)SFLER ddPTM_HeLa_Curcumin_4h_R1 2 NKGSSFLER 9 1 A0A087WZM6;A0A087WVX1;A0A087X0T9;P0C875 A0A087WZM6 FAM228B Protein FAM228B 1 0 NKGS(0.5)S(0.5)FLER;NKGS(0.5)S(0.5)FLER ; 97.452 0.0057268 0 3748.52 3076.75 3474.1 3254.5 3749.4 4318.1 3476.2 3085.2 3961.2 3472.4 TRUE FALSE FALSE 3451.820687 3342.69056 3602.853202 3241.033741 3704.690854 3422.477385 3573.732816 4025.863277 3526.66627 3593.065642 0.96068957 0.930317142 1.002724014 0.90202464 1.031066845 0.952522922 0.994619407 1.120453585 0.981520134 1 11.81099958 -4.270632737 3.681214141 0.975177503 1.134919956 0.611661195 0.03556278 0.128543048 3.226819034 0.004651542 0.055229181 5.36E-05 4.270632737 0.159742453 NKGTSDSSSGNVS(ph)EGESPPDSQEDSFQGR ddPTM_HeLa_Curcumin_4h_R1 2 NKGTSDSSSGNVSEGESPPDSQEDSFQGR 29 1 S5FZ81;Q8WUB8-3;Q8WUB8-2;Q8WUB8 S5FZ81 PHF10 PHD finger protein 10 1 0 NKGTSDSS(0.001)S(0.003)GNVS(0.993)EGES(0.001)PPDSQEDSFQGR;NKGT(0.01)S(0.007)DS(0.023)S(0.023)S(0.017)GNVS(0.808)EGES(0.111)PPDSQEDSFQGR ; 108.69 1.04E-10 52659000 3224.2 2595.4 2701 2933.2 2768.2 3892.6 2930.8 2345.44 3413.8 2700.2 TRUE FALSE FALSE 2969.001168 2819.734811 2801.101436 2921.063196 2735.191023 3085.230881 3013.03036 3060.553859 3039.314681 2794.031749 1.062622559 1.009199273 1.002530282 1.045465284 0.978940566 1.104221841 1.07838086 1.095389793 1.087788169 1 11.4481327 -5.242526163 24.99493362 1.024861675 1.091235841 0.486431864 0.031035679 498.1790392 658371.8179 0.004038557 0.010277955 5.72E-06 5.242526163 0.066374166 NKHEAMITDLEER ddPTM_HeLa_Curcumin_4h_R1 5 NKHEAMITDLEER 13 1 P35579 P35579 MYH9 Myosin-9 0 0 ;;;; ;;;; 112.02 0.00023949 60075000 18041.1 16203.9 17538.7 17983.7 16908.1 20289.9 16629.9 14341.8 19582.8 18093.8 FALSE FALSE TRUE 16613.1279 17604.49291 18188.69965 17909.28821 16706.48195 16081.54603 17096.49024 18714.5488 17434.61583 18722.5582 0.887332154 0.940282451 0.971485812 0.956562026 0.892318334 0.858939566 0.913149264 0.999572206 0.93120906 1 14.19248995 -5.77191116 24.98585559 0.947682041 0.911716209 0.114439532 0.042700407 396.7971901 946766.3624 0.007894118 0.014423988 1.69E-06 5.77191116 -0.035965832 NKHPDEDAVEAEGHEVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 NKHPDEDAVEAEGHEVKR 18 2 Q9NY27-2;Q9NY27-3;Q9NY27;H7C559;C9IZ04 Q9NY27-2 PPP4R2 Serine/threonine-protein phosphatase 4 regulatory subunit 2 0 1 ; NKHPDEDAVEAEGHEVK(1)R;NKHPDEDAVEAEGHEVK(1)R 78.902 0.0022653 5102200 4359.9 3686 3362.6 3671.3 3911.9 5035.4 3359.8 4333.5 4180.7 3462.6 FALSE TRUE FALSE 4014.809314 4004.601416 3487.220914 3656.109133 3865.253147 3991.001279 3454.066946 5654.764201 3722.08767 3582.925092 1.120539562 1.117690522 0.973288814 1.02042578 1.078798202 1.113894702 0.96403549 1.578253537 1.038840493 1 11.80692217 -4.255366369 24.99913819 1.054636843 1.578253767 0.888852302 0.056254273 175.7723011 723534.6342 0.008620282 0.105269933 5.55E-05 4.255366369 0.523616924 NKLAS(ph)QLT(ph)ESS(ph)QT(ph)SIS(ph)LESDLK ddPTM_HeLa_Curcumin_4h_R1 1 NKLASQLTESSQTSISLESDLK 22 1 Q562F6-2;Q562F6 Q562F6-2 SGOL2 Shugoshin-like 2 5 0 NKLAS(0.84)QLT(0.861)ES(0.429)S(0.84)QT(0.507)S(0.507)IS(0.508)LES(0.508)DLK 49.34 0.0075949 0 273.68 378.29 305.27 273.9 349.19 251.87 284.55 238.5 323.82 252.3 TRUE FALSE FALSE 252.0179392 410.987702 316.5835747 272.7666744 345.0261373 199.6293228 292.5337072 311.2175521 288.2977562 261.0674062 0.965336665 1.574258955 1.212650707 1.044813209 1.321597906 0.764665822 1.120529412 1.192096542 1.104303905 1 8.028278541 NKLEGDS(ph)DVDS(ph)ELEDRVDGVK ddPTM_HeLa_Curcumin_4h_R1 2 NKLEGDSDVDSELEDRVDGVK 21 2 Q92614;Q92614-2 Q92614 MYO18A Unconventional myosin-XVIIIa 2 0 NKLEGDS(1)DVDS(1)ELEDRVDGVK;NKLEGDS(1)DVDS(1)ELEDRVDGVK ; 63.906 0.005117 46463000 7195.4 5445.7 6325.4 6574.8 6262.3 6938.4 7012.6 2504.7 8198.8 6326.5 TRUE FALSE FALSE 6625.876497 5916.402042 6559.824888 6547.59522 6187.626163 5499.297628 7209.354683 3268.3715 7299.412152 6546.345404 1.01214893 0.90377175 1.002059085 1.000190918 0.945203129 0.840056136 1.1012793 0.499266583 1.115036208 1 12.67647401 -4.253248438 24.99774216 0.988127379 0.499266342 0.781480769 0.078006602 294.6539382 899227.3668 0.008728241 0.132180342 5.58E-05 4.253248438 -0.488861037 NKLEGDSDVDS(ph)ELEDRVDGVK ddPTM_HeLa_Curcumin_4h_R1 1 NKLEGDSDVDSELEDRVDGVK 21 2 Q92614;Q92614-2 Q92614 MYO18A Unconventional myosin-XVIIIa 1 0 NKLEGDS(0.099)DVDS(0.901)ELEDRVDGVK 70.679 0.0022085 27534000 1471.8 1183.2 1259.1 1629.2 1185.9 1787.2 1311 1784 1443.9 1476.7 TRUE FALSE FALSE 1355.305477 1285.470536 1305.763354 1622.458802 1171.758917 1416.514574 1347.783132 2327.933387 1285.507782 1528.015215 0.886971192 0.841268152 0.854548659 1.061808015 0.766850294 0.927029103 0.88204824 1.523501445 0.841292528 1 10.57744319 -4.259025627 24.98252495 0.923627381 1.523501657 0.830564906 0.084216237 65.57992832 678714.5256 0.011461333 0.103389611 5.51E-05 4.259025627 0.599874276 NKPGPNIES(ph)GNEDDDASFK ddPTM_HeLa_Curcumin_4h_R1 9 NKPGPNIESGNEDDDASFK 19 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 0 NKPGPNIES(0.998)GNEDDDAS(0.002)FK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(0.996)GNEDDDAS(0.004)FK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(0.999)GNEDDDAS(0.001)FK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(1)GNEDDDASFK;NKPGPNIES(1)GNEDDDASFK ;;;;;;;; 120.44 0.0001002 4169215000 25607.4 20349.21 21046.01 22247.05 22758.55 26817.3 21577.9 18892.16 25996.12 22682.43 TRUE FALSE FALSE 23580.54727 22108.10504 21825.99364 22154.9976 22487.16916 21255.08969 22183.3178 24652.29262 23144.41068 23470.64275 1.004682638 0.941947149 0.929927394 0.943945074 0.958097713 0.905603221 0.945151696 1.050345867 0.98610042 1 14.51856973 -7.265451055 24.62993399 1.002211247 0.950299209 0.22713452 0.035902755 235.023396 1442938.309 0.005801185 0.006756359 5.43E-08 7.265451055 -0.051912038 NKPLEQS(ph)VEDLSK ddPTM_HeLa_Curcumin_4h_R1 1 NKPLEQSVEDLSK 13 1 O95466;O95466-2;O95466-3 O95466 FMNL1 Formin-like protein 1 1 0 NKPLEQS(0.832)VEDLS(0.168)K 178.03 0.0017836 8090200 2454.6 2362.7 2200.4 2294.8 2481.3 2793.6 2410.9 1260.5 2413.6 2453.9 TRUE FALSE FALSE 2260.31582 2566.92126 2281.94876 2285.304726 2451.712118 2214.17587 2478.543365 1644.820647 2148.834119 2539.172842 0.890178007 1.010928133 0.898697687 0.900019364 0.965555427 0.872006755 0.976122351 0.647778135 0.846273276 1 11.31014289 -4.257418354 24.88318411 0.942340012 0.647778012 0.69630515 0.055046672 142.7171229 883134.065 0.007084366 0.072373396 5.53E-05 4.257418354 -0.294562 NKPLEQS(ph)VEDLSKGPPSSVPK ddPTM_HeLa_Curcumin_4h_R1 1 NKPLEQSVEDLSKGPPSSVPK 21 2 O95466;O95466-2;O95466-3 O95466 FMNL1 Formin-like protein 1 1 0 NKPLEQS(0.99)VEDLS(0.009)KGPPS(0.001)SVPK 83.059 0.00070591 19370000 2216.7 1822.7 1838.6 1827.6 1652.2 1636.4 1455.9 1151.2 2436.4 2176.5 TRUE FALSE FALSE 2041.245856 1980.246066 1906.740133 1820.037875 1632.498594 1296.992194 1496.748636 1502.195581 2169.133016 2252.133213 0.906361064 0.879275726 0.846637367 0.80813953 0.724867688 0.575894972 0.66459152 0.667010092 0.963145964 1 11.13707645 -6.147975988 0.513748172 0.976823196 0.595603002 0.918135826 0.038196197 0.218109416 0.105475385 0.011377242 0.03667903 7.11E-07 6.147975988 -0.381220194 NKPLEQSVEDLS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 NKPLEQSVEDLSK 13 1 O95466;O95466-2;O95466-3 O95466 FMNL1 Formin-like protein 1 1 0 NKPLEQS(0.068)VEDLS(0.932)K 152.11 0.0044574 8329300 1904.2 2023.4 2059 1987.7 2208.2 2486.4 1718.6 1054.3 2555.6 1957.9 TRUE FALSE FALSE 1753.480561 2198.29368 2135.308351 1979.475424 2181.868657 1970.692612 1766.819291 1375.751217 2275.257074 2025.936879 0.86551589 1.085075109 1.053985627 0.977066682 1.076967738 0.972731497 0.872099871 0.679069141 1.123064147 1 10.98437351 -4.345980322 2.379485986 0.96892132 0.63964068 0.577002167 0.08259171 0.275935916 2.125955543 0.011738372 0.171828384 4.51E-05 4.345980322 -0.32928064 NKPLS(ph)PIKLTPTSVLDYFGTGSVQR ddPTM_HeLa_Curcumin_4h_R1 1 NKPLSPIKLTPTSVLDYFGTGSVQR 25 2 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 0 NKPLS(0.981)PIKLT(0.018)PTSVLDYFGTGSVQR 72.271 0.00017515 144820000 297.61 315.04 472.01 433.3 380.69 525.89 362.4 263.5 486.71 584.8 TRUE FALSE FALSE 274.0538545 342.2706538 489.5031058 431.5071194 376.1505204 416.814486 372.5679687 343.839937 433.3191307 605.1217565 0.452890433 0.565622786 0.808933245 0.713091398 0.621611298 0.68881094 0.615690916 0.568216121 0.716085856 1 9.241081646 -9.488495144 1.22812553 1.000291601 0.617553674 0.252172946 0.124105641 0.235368552 0.63448604 0.075635103 0.018392068 3.25E-10 9.488495144 -0.382737927 NKPPPPPPASASPSAVPNGPQS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 NKPPPPPPASASPSAVPNGPQSPK 24 1 H0Y7W6 H0Y7W6 FNBP1 1 0 NKPPPPPPASASPSAVPNGPQS(1)PK;NKPPPPPPASASPSAVPNGPQS(1)PK ; 174.77 1.07E-10 45187000 13255.9 11260.6 12089.4 12850.7 11448.4 12627.1 10399.2 6713.2 13850.2 12037.9 TRUE FALSE FALSE 12206.68153 12233.91609 12537.4438 12797.52721 11311.88531 10008.09712 10690.97356 8760.023776 12330.86771 12456.21613 0.979967062 0.982153486 1.006521055 1.027400864 0.908131746 0.803462064 0.858284206 0.703265236 0.989936878 1 13.60457826 -5.396500161 2.235835175 0.993364358 0.787701899 0.857869379 0.038061593 0.078204717 0.7574432 0.005178707 0.013902533 4.01E-06 5.396500161 -0.205662459 TAESQT(ph)PTPSATSFFSGK ddPTM_HeLa_Curcumin_4h_R1 1 TAESQTPTPSATSFFSGK 18 0 P55265-5;P55265;P55265-4;A0A3B3ITG9;A0A3B3ISX1;A0A3B3IRQ9;P55265-3;P55265-2 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 0 TAES(0.046)QT(0.75)PT(0.182)PS(0.021)ATSFFSGK 183.6 1.25E-06 7151300 859.05 783.03 778.6 636.83 682.37 1035.3 1298.3 4509.3 754.74 623.19 TRUE FALSE FALSE 791.055286 850.7116241 807.4556009 634.1949662 674.2331834 820.5671098 1334.726804 5884.164812 671.9469103 644.8458061 1.226735568 1.31924813 1.252168492 0.983483121 1.04557272 1.272501274 2.069838698 9.124917548 1.042027263 1 9.332810418 -4.248962553 3.201479328 1.136100016 10.40995533 0.997397009 0.121561243 0.015834748 0.246507016 0.022190617 0.370290509 5.64E-05 4.248962553 9.273855314 up NKQTYSTEPNNLK ddPTM_HeLa_Curcumin_4h_R1 1 NKQTYSTEPNNLK 13 1 H0YMF4;H0YKD8;P46779-4;P46779-5;P46779;P46779-2;P46779-3;H0YLP6 H0YMF4 RPL28 60S ribosomal protein L28 0 0 85.973 0.0052383 0 474.65 492.65 554.14 603.82 544.41 773.2 612.56 771.32 815.24 763.09 FALSE FALSE TRUE 437.0809517 535.2324708 574.6769159 601.3215528 537.9182663 612.8296042 629.746785 1006.491917 725.8102116 789.6073207 0.553542172 0.677846389 0.727800896 0.761545058 0.681247821 0.776119456 0.797544258 1.274673994 0.919204005 1 9.624991555 -4.258241482 4.212639307 0.76279053 1.316663702 0.625890974 0.118236441 0.156942672 6.241159568 0.022966894 0.261872064 5.52E-05 4.258241482 0.553873171 NKS(ph)TESLQANVQR ddPTM_HeLa_Curcumin_4h_R1 1 NKSTESLQANVQR 13 1 P26373;J3QSB4 P26373 RPL13 60S ribosomal protein L13 1 0 NKS(0.779)T(0.145)ES(0.076)LQANVQR 81.651 0.0089655 24530000 3194.8 3034.6 2983.6 3034.7 2968.6 3741.5 2551.7 2240.3 3529.2 3218.7 TRUE FALSE FALSE 2941.928209 3296.897302 3094.174841 3022.143215 2933.201384 2965.470725 2623.293834 2923.357157 3142.05559 3330.549585 0.883316141 0.989895877 0.929028306 0.907400757 0.880695906 0.890384799 0.787645933 0.877740169 0.943404537 1 11.70154455 -13.52287874 0.017552949 2.095802686 9.92E-15 0.49207262 0.041510017 1982.447598 2.808508163 214.5583873 130.5904373 3.00E-14 13.52287874 -2.095802686 NLAPHHAS(ph)PDPPAPPASASDPHR ddPTM_HeLa_Curcumin_4h_R1 2 NLAPHHASPDPPAPPASASDPHR 23 0 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 NLAPHHAS(1)PDPPAPPASASDPHR;NLAPHHAS(1)PDPPAPPASASDPHR ; 104.68 9.10E-06 31078100 7614.2 6421.8 6153.3 5836.7 6278.3 7790.2 6355.4 5284.6 6984.7 6688.7 TRUE FALSE FALSE 7011.528036 6976.871777 6381.346711 5812.549282 6203.435373 6174.424706 6533.715419 6895.850213 6218.495885 6921.131827 1.0130609 1.008053589 0.922009127 0.839826408 0.8963036 0.892111993 0.944024125 0.996347185 0.898479619 1 12.75679227 -6.734626189 5.538855183 1.006602842 0.910453064 0.217247825 0.050850935 0.09564649 8.109546541 0.006205299 0.008659124 1.84E-07 6.734626189 -0.096149778 SIT(ph)SPPSTSTTK ddPTM_HeLa_Curcumin_4h_R1 1 SITSPPSTSTTK 12 0 C9JWJ8;K7EN08;Q14938-6;Q14938-5;Q14938-3;Q14938-2;Q14938-4;Q14938 C9JWJ8 NFIX Nuclear factor 1;Nuclear factor 1 X-type 1 0 S(0.006)IT(0.477)S(0.477)PPS(0.023)T(0.012)S(0.003)T(0.001)TK 120.55 0.010173 6031900 3161.1 2515.8 2734.3 2858 3321.4 3720.8 2367.2 1042 3626.6 3140.3 TRUE FALSE FALSE 2910.895599 2733.254542 2835.635563 2846.174353 3281.794474 2949.064138 2433.617261 1359.701003 3228.771053 3249.425191 0.895818623 0.841150167 0.872657592 0.87590087 1.009961541 0.907564866 0.748937771 0.418443547 0.993643756 1 11.66596882 -4.314256657 1.880706032 0.933954465 0.290563398 0.884294462 0.056042126 0.190817262 0.751167057 0.009263596 0.206087234 4.85E-05 4.314256657 -0.643391067 down NLDADLVRDRT(ph)PPHLLYSDRDR ddPTM_HeLa_Curcumin_4h_R1 1 NLDADLVRDRTPPHLLYSDRDR 22 3 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 0 NLDADLVRDRT(1)PPHLLYSDRDR 57.537 0.0036449 5955700 2065.4 2063.8 1905.7 2250.4 1906.7 3215.1 2096.8 1465.9 3056.5 2403.5 TRUE FALSE FALSE 1901.921411 2242.185676 1976.326918 2241.088441 1883.963848 2548.252018 2155.630565 1912.846162 2721.209597 2487.021446 0.764738645 0.90155462 0.794656163 0.901113436 0.757518135 1.024620042 0.8667519 0.76913135 1.094164106 1 11.28020323 -9.531133474 1.2866256 1.000107982 0.842334033 0.443178647 0.084942294 0.395688025 1.171663996 0.054470407 0.012976399 2.94E-10 9.531133474 -0.157773949 NLDDGIDDER ddPTM_HeLa_Curcumin_4h_R1 2 NLDDGIDDER 10 0 P11940;P11940-2;E7EQV3;A0A087WTT1;E7ERJ7;H0YAR2;Q9H361;H0YAP2 P11940 PABPC1;PABPC3 Polyadenylate-binding protein 1;Polyadenylate-binding protein;Polyadenylate-binding protein 3 0 0 ; ; 248.88 2.51E-23 196823000 5422.2 4702.4 4778.9 5206.2 5369.7 6561.3 5319.7 5017.5 5619.4 4443.7 FALSE FALSE TRUE 4993.027149 5108.854503 4956.010238 5184.658124 5305.669835 5200.412419 5468.956465 6547.312652 5002.965879 4598.118244 1.085884895 1.11107506 1.077834448 1.127560852 1.153878511 1.1309871 1.189390132 1.423911327 1.088046373 1 12.16682785 -1 0.364694722 1.038116914 5.369138305 0.836339085 0.04307831 15.50830845 0.191604905 0.012460863 47.42281908 0.1 1 4.33102139 NLDDGIDDERLR ddPTM_HeLa_Curcumin_4h_R1 6 NLDDGIDDERLR 12 1 P11940;P11940-2;E7EQV3;A0A087WTT1;E7ERJ7;H0YAR2;Q9H361;H0YAP2 P11940 PABPC1;PABPC3 Polyadenylate-binding protein 1;Polyadenylate-binding protein;Polyadenylate-binding protein 3 0 0 ;;;;; ;;;;; 174.72 0.00011999 681805800 30016.3 24871.1 25690.2 27593.3 30232 34162.2 27855.7 27291.6 35103.5 30040.6 FALSE FALSE TRUE 27640.47818 27020.84706 26642.30141 27479.12624 29871.50315 27076.57463 28637.25597 35612.6832 31252.73387 31084.50861 0.889204283 0.869270523 0.857092571 0.884013532 0.960977171 0.871063299 0.921270988 1.145673031 1.005411868 1 14.92390815 -4.260729191 24.33973933 0.925652638 1.145673121 0.630652771 0.05203634 23.97011599 821258.344 0.008239168 0.066031797 5.49E-05 4.260729191 0.220020483 NLDDTIDDEKLR ddPTM_HeLa_Curcumin_4h_R1 1 NLDDTIDDEKLR 12 1 P0CB38;H0Y5F5;B1ANR0;Q13310-2;Q13310;Q13310-3;H0YEU6 P0CB38;H0Y5F5 PABPC4L;PABPC4 Polyadenylate-binding protein 4-like;Polyadenylate-binding protein;Polyadenylate-binding protein 4 0 0 148.89 0.00054021 12844000 3762.4 3753.5 3836.1 3813.3 4274.5 4562.1 3949.1 3636 4439.3 3653.7 FALSE FALSE TRUE 3464.60207 4077.935815 3978.269241 3797.521575 4223.529379 3615.869035 4059.901118 4744.599662 3952.319897 3780.665803 0.916399981 1.078629011 1.052266835 1.004458414 1.117139044 0.956410649 1.073858767 1.254964048 1.045403139 1 11.88442461 -1 0.508431852 0.976003044 9.367015129 0.441010396 0.066501471 56.12135908 0.527134205 0.013377411 508.031071 0.1 1 8.391012084 NLDIERPTYTNLNR ddPTM_HeLa_Curcumin_4h_R1 3 NLDIERPTYTNLNR 14 1 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;Q9NY65-2;Q9NY65;C9J2C0;C9JDS9;P68363;P68366-2;P68366 Q9BQE3;P68363;P68366-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E;TUBA8;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 0 ;; ;; 126.32 0.0010891 419339000 9964.6 9096.5 8900.3 10238.9 8813.5 11988.1 8502.9 8431.1 9816.1 9696.8 FALSE FALSE TRUE 9175.891395 9882.760927 9230.152948 10196.53414 8708.404769 9501.632926 8741.46849 11001.70358 8739.298389 10033.76308 0.914501501 0.984950596 0.919909397 1.016222335 0.867910145 0.946966044 0.871205391 1.096468343 0.870989112 1 13.29257516 -9.560154681 1.326007802 1.00007251 0.944340437 0 0.076552887 0.834489812 2.623840559 0.041656254 0.009759997 2.75E-10 9.560154681 -0.055732073 NLDK(ac)SIDNK ddPTM_HeLa_Curcumin_4h_R1 2 NLDKSIDNK 9 1 P11940;P11940-2;E7EQV3;A0A087WTT1;E5RGH3;B1ANR1;E5RJB9;E5RH24;H0YEQ8;P0CB38;H0Y5F5;B1ANR0;Q13310-2;Q13310;Q13310-3 P11940;P0CB38;H0Y5F5 PABPC1;PABPC4;PABPC4L Polyadenylate-binding protein 1;Polyadenylate-binding protein;Polyadenylate-binding protein 4-like;Polyadenylate-binding protein 4 0 1 ; NLDK(1)SIDNK;NLDK(1)SIDNK 107.55 0.0043416 9439300 7215.7 6768.4 6429.3 7061.5 6839.6 8778.3 7020.8 6435.1 7629.6 7387.5 FALSE TRUE FALSE 6644.569731 7353.430337 6667.575514 7032.281384 6758.042237 6957.581628 7217.784752 8397.132366 6792.651968 7644.215075 0.869228517 0.961960157 0.872238084 0.919948133 0.884072749 0.910176069 0.94421529 1.098495043 0.888600321 1 12.90015265 -4.26484214 4.029892971 0.927278933 1.113076174 0.63594788 0.04075367 0.152623473 5.207021681 0.007317364 0.082004689 5.43E-05 4.26484214 0.185797241 NLDNVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 NLDNVSPK 8 0 A0A0A0MSG8;P78563-6;P78563-2;P78563-3;P78563-4;P78563;P78563-5 A0A0A0MSG8 ADARB1 Double-stranded RNA-specific editase 1 1 0 NLDNVS(1)PK;NLDNVS(1)PK ; 103.21 0.013278 74313000 19514.7 16125.4 18897.5 18070.8 18532.2 18896.4 16098.2 14690.3 17656 16651.4 TRUE FALSE FALSE 17970.0909 17519.20772 19597.85797 17996.02782 18311.21562 14977.07363 16549.87217 19169.30484 15719.18097 17230.03491 1.042951509 1.016783066 1.137424159 1.04445684 1.062749769 0.869242211 0.960524587 1.112551712 0.912312776 1 14.072638 NLDSLEEDLDFLR ddPTM_HeLa_Curcumin_4h_R1 1 NLDSLEEDLDFLR 13 0 P61758-2;P61758 P61758-2 VBP1 Prefoldin subunit 3 0 0 195.72 5.11E-22 0 545.01 424.29 561.81 566.73 694.84 383.07 424.64 324.81 669.94 393.15 FALSE FALSE TRUE 501.8718834 460.963737 582.6311728 564.3850214 686.5544868 303.6169639 436.5542555 423.8430738 596.4492581 406.8119332 1.233670506 1.133112624 1.432188009 1.387336445 1.687645889 0.746332492 1.073110742 1.041864899 1.466154774 1 8.668218189 -3.142439008 12.32096775 1.158915429 1.187040705 0 0.268998541 0 0 0.034047187 0 0.000720379 3.142439008 0.028125276 NLEEEENLGKGEYQES(ph)LRSLEEEGQELPQSADVQR ddPTM_HeLa_Curcumin_4h_R1 3 NLEEEENLGKGEYQESLRSLEEEGQELPQSADVQR 35 2 P48681 P48681 NES Nestin 1 0 NLEEEENLGKGEY(0.107)QES(0.446)LRS(0.446)LEEEGQELPQSADVQR;NLEEEENLGKGEY(0.06)QES(0.588)LRS(0.352)LEEEGQELPQSADVQR;NLEEEENLGKGEY(0.058)QES(0.465)LRS(0.465)LEEEGQELPQS(0.011)ADVQR ;; 81.297 2.53E-08 82685000 3594.52 2815.62 3015.58 3422.03 3188.46 4391.05 3607.86 4320.19 3855.51 3297.24 TRUE FALSE FALSE 3310.009949 3058.989647 3127.340048 3407.870547 3150.439697 3480.296733 3709.086842 5637.396043 3432.570199 3411.818845 0.970159935 0.896586186 0.916619607 0.998842759 0.923390086 1.020070787 1.087128892 1.652314 1.006082197 1 11.73632533 -4.174355762 2.125698496 0.971941784 1.945930529 0.9631008 0.04009841 0.12310094 0.503213991 0.005924041 0.246823198 6.69E-05 4.174355762 0.973988746 NLEEEENLGKGEYQESLRS(ph)LEEEGQELPQSADVQR ddPTM_HeLa_Curcumin_4h_R1 1 NLEEEENLGKGEYQESLRSLEEEGQELPQSADVQR 35 2 P48681 P48681 NES Nestin 1 0 NLEEEENLGKGEY(0.019)QES(0.073)LRS(0.902)LEEEGQELPQS(0.007)ADVQR 80.022 2.87E-08 21738000 898.5 465.02 903.87 721.02 787.72 1375.8 863.07 1136.5 903.45 737.22 TRUE FALSE FALSE 827.3827769 505.2142567 937.3682173 718.0366103 778.3269535 1090.443572 887.2854214 1483.013618 804.3437953 762.8383401 1.084610898 0.662282203 1.228790122 0.941269693 1.020303926 1.429455645 1.163136899 1.944073259 1.054409241 1 9.575233545 -1 0.75237275 1.018535091 161.0658792 0.711636881 0.17393313 137.3171433 0.549974664 0.025611951 37297.06576 0.1 1 160.0473442 NLEELEEKS(ph)TTPPPAEPVSLPQEPPKPR ddPTM_HeLa_Curcumin_4h_R1 1 NLEELEEKSTTPPPAEPVSLPQEPPKPR 28 2 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 0 NLEELEEKS(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR 56.172 0.001216 62562000 2280 1619 1843.4 1986.3 1706.4 2150.7 1451.5 1768.9 2744.1 2474.7 TRUE FALSE FALSE 2099.535594 1758.939146 1911.718026 1978.081217 1686.052294 1704.620577 1492.225183 2308.229467 2443.079095 2560.695641 0.819908294 0.68689895 0.746561987 0.772478066 0.658435258 0.665686523 0.582742111 0.901407192 0.954068518 1 11.32232007 -8.179390479 0.526422742 1.002312235 0.694926628 0.598244344 0.083034991 0.362176672 0.228268404 0.047741951 0.025029745 6.62E-09 8.179390479 -0.307385607 NLEELEEKST(ph)TPPPAEPVSLPQEPPK ddPTM_HeLa_Curcumin_4h_R1 4 NLEELEEKSTTPPPAEPVSLPQEPPK 26 1 Q9UN86-2;Q9UN86 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 0 NLEELEEKS(0.043)T(0.57)T(0.386)PPPAEPVS(0.002)LPQEPPK;NLEELEEKS(0.118)T(0.441)T(0.441)PPPAEPVSLPQEPPK;NLEELEEKS(0.115)T(0.435)T(0.435)PPPAEPVS(0.014)LPQEPPK;NLEELEEKS(0.014)T(0.493)T(0.493)PPPAEPVSLPQEPPK ;;; 112.13 6.39E-08 101528000 24931.6 18512 17942.4 22038.4 15315.7 24573.4 18480.3 20724.1 27865.8 24072 TRUE FALSE FALSE 22958.23755 20112.09479 18607.36113 21947.21094 15133.07028 19476.59984 18998.80748 27042.78269 24808.99146 24908.50021 0.921702927 0.807439012 0.747028563 0.881113305 0.607546426 0.781925836 0.762743936 1.085684905 0.996005028 1 14.60435054 -7.478807494 1.606051634 0.973426706 0.798324553 0.294155156 0.11522213 0.305528279 1.553206461 0.022077488 0.024033722 3.32E-08 7.478807494 -0.175102153 NLEELEEKST(ph)TPPPAEPVSLPQEPPKPR ddPTM_HeLa_Curcumin_4h_R1 1 NLEELEEKSTTPPPAEPVSLPQEPPKPR 28 2 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 0 NLEELEEKS(0.178)T(0.584)T(0.237)PPPAEPVSLPQEPPKPR 71.811 9.55E-05 323080000 5268.1 3954.8 3676.6 4919.8 3065.4 5193.3 3829.5 3947.3 6512.9 4926.2 TRUE FALSE FALSE 4851.124326 4296.63529 3812.85803 4899.443171 3028.847107 4116.151039 3936.945463 5150.813599 5798.451164 5097.385083 0.951688806 0.842909692 0.748002744 0.96116795 0.594196251 0.807502469 0.772346095 1.010481554 1.137534455 1 12.31554163 -7.2777376 2.458408133 0.980450278 0.808379034 0.38087577 0.118481702 0.23052208 2.657936157 0.018156475 0.02138278 5.28E-08 7.2777376 -0.172071244 NLEELEEKSTT(ph)PPPAEPVSLPQEPPKPR ddPTM_HeLa_Curcumin_4h_R1 2 NLEELEEKSTTPPPAEPVSLPQEPPKPR 28 2 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 0 NLEELEEKS(0.028)T(0.269)T(0.703)PPPAEPVSLPQEPPKPR;NLEELEEKS(0.046)T(0.411)T(0.544)PPPAEPVSLPQEPPKPR ; 89.345 7.72E-07 487198000 11516.7 7940 8178.4 9608.2 6993.1 11196.7 8865.6 9197.6 13803.9 10351.6 TRUE FALSE FALSE 10605.14104 8626.29822 8481.498698 9568.443814 6909.71185 8874.378207 9114.344875 12001.9059 12289.64671 10711.31733 0.990087467 0.805344287 0.79182592 0.893302245 0.64508516 0.828504836 0.850907932 1.120488314 1.147351565 1 13.3868483 -7.271337692 22.35133403 0.995319105 0.839077008 0.335645618 0.121058248 145.4612889 328464.6342 0.018393923 0.021199281 5.35E-08 7.271337692 -0.156242097 ATQVGEK(ac)TPK ddPTM_HeLa_Curcumin_4h_R1 2 ATQVGEKTPK 10 1 P50552;K7EM16 P50552 VASP Vasodilator-stimulated phosphoprotein 0 1 ; ATQVGEK(1)TPK;ATQVGEK(1)TPK 187.42 2.17E-16 5223400 3658.8 4201.8 4474.5 3884.8 4170.3 6041.3 5663.7 7359.5 3843.4 4394.9 FALSE TRUE FALSE 3369.202119 4564.984869 4640.328906 3868.725727 4120.571896 4788.266281 5822.608179 9603.377671 3421.788636 4547.622448 0.740871116 1.003817912 1.020385698 0.850713922 0.906093666 1.052916405 1.280363145 2.111735919 0.752434635 1 12.15089677 -3.882767809 1.164450599 0.893506967 3.794868119 0.937626355 0.094296927 0.642462702 0.394431085 0.016459551 2.797540519 0.000130988 3.882767809 2.901361152 up NLEQILNGGES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 NLEQILNGGESPK 13 0 G3V340;Q13033-2;Q13033;G3V3G7 G3V340 STRN3 Striatin-3 1 0 NLEQILNGGES(1)PK;NLEQILNGGES(1)PK ; 117.13 0.0027714 134649000 7097.7 6430 8155.9 7527.3 8033.5 7502.4 7110.6 7228.7 7239.7 6846.1 TRUE FALSE FALSE 6535.909556 6985.780548 8458.164829 7496.154027 7937.705759 5946.317671 7310.104299 9432.697353 6445.523023 7084.001465 0.922629617 0.986134825 1.193981236 1.058180756 1.120511592 0.839400966 1.031917389 1.331549323 0.909870368 1 12.7903488 -6.974986499 24.58363148 0.962985986 1.081531318 0.24555214 0.120053026 240.8681154 236727.8289 0.01905166 0.025038246 1.06E-07 6.974986499 0.118545332 NLEQILNGGES(ph)PKQK ddPTM_HeLa_Curcumin_4h_R1 1 NLEQILNGGESPKQK 15 1 G3V340;Q13033-2;Q13033 G3V340 STRN3 Striatin-3 1 0 NLEQILNGGES(1)PKQK 146.3 0.0045815 38695000 1677.3 1305.8 1737.1 1349.3 1304.1 2066.7 1575.7 1555.4 1822.9 1503.1 TRUE FALSE FALSE 1544.539935 1418.667533 1801.478454 1343.716954 1288.549459 1638.043123 1619.909901 2029.6343 1622.932431 1555.332613 0.993060855 0.912131284 1.158259294 0.863941862 0.828471961 1.053178664 1.041519922 1.304951933 1.043463255 1 10.60300742 -4.140978514 1.858086776 0.983430085 1.481096875 0.533550575 0.090664525 0.69151158 1.874343834 0.012099148 0.658196356 7.23E-05 4.140978514 0.49766679 NLES(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 1 NLESPEK 7 0 P26374 P26374 CHML Rab proteins geranylgeranyltransferase component A 2 1 0 NLES(1)PEK 105.17 0.017365 11506000 4314.8 3524.9 4520.3 4275.4 5340.7 4446.6 3548.1 2396.2 3296.2 3253.9 TRUE FALSE FALSE 3973.279027 3829.576649 4687.826294 4257.709528 5277.015641 3524.325036 3647.650137 3126.790349 2934.615107 3366.972783 1.18007459 1.137394596 1.392297056 1.264551216 1.567287882 1.046734044 1.083361931 0.928665169 0.871588604 1 11.71723634 -8.714889059 0.77825709 1.007818752 1.211151004 0.238943052 0.176870757 0.866979602 1.036835308 0.093926533 0.03808976 1.93E-09 8.714889059 0.203332251 NLFASFPTEES(ph)SINYTFKTPEKAK ddPTM_HeLa_Curcumin_4h_R1 1 NLFASFPTEESSINYTFKTPEKAK 24 2 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 NLFASFPT(0.003)EES(0.451)S(0.451)INY(0.032)T(0.038)FKT(0.025)PEKAK 58.796 0.0020004 47944000 6728.6 4411 4202.4 4885.3 3464.5 7312.5 4176 3471.9 6669.8 5067.9 TRUE FALSE FALSE 6196.02421 4792.267185 4358.144641 4865.085923 3423.1881 5795.805071 4293.167321 4530.466327 5938.139627 5244.009148 1.181543364 0.913855611 0.831071136 0.927741693 0.652780726 1.105224058 0.818680365 0.863931812 1.132366375 1 12.35645449 -7.112077889 5.585960611 1.085323863 0.868638299 0.466762427 0.113567284 0.161727353 6.982844457 0.019329295 0.023797868 7.73E-08 7.112077889 -0.216685563 NLFASFPTEESSINYTFKT(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 2 NLFASFPTEESSINYTFKTPEK 22 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 NLFAS(0.001)FPT(0.034)EES(0.12)S(0.12)INY(0.296)T(0.08)FKT(0.35)PEK;NLFASFPT(0.009)EES(0.191)S(0.124)INY(0.006)T(0.072)FKT(0.597)PEK ; 73.435 0.0015029 621410000 4295.8 3640.8 4501.1 4103.5 4498.5 4668.4 3965.1 1425.04 4512.1 3746.7 TRUE FALSE FALSE 3955.782897 3955.494529 4667.914726 4086.520804 4444.858326 3700.121216 4076.350034 1859.528136 4017.133919 3876.897546 1.020347546 1.020273165 1.204033553 1.054069847 1.146498785 0.954402631 1.051446417 0.479643352 1.036172318 1 11.92068689 -4.260341419 24.96080322 1.033961788 0.479643172 0.853989887 0.070823518 25.82114279 586932.7085 0.010001561 0.082206513 5.49E-05 4.260341419 -0.554318616 NLFASFPTEESSINYTFKT(ph)PEKAK ddPTM_HeLa_Curcumin_4h_R1 1 NLFASFPTEESSINYTFKTPEKAK 24 2 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 NLFASFPT(0.006)EES(0.01)S(0.01)INY(0.085)T(0.098)FKT(0.79)PEKAK 55.204 0.0041508 41572000 2608 1648.2 1358.4 2189.6 903.9 2111.6 1248.3 758.66 3013.7 2157 TRUE FALSE FALSE 2401.574048 1790.663064 1408.743499 2180.540015 893.1215829 1673.630357 1283.323938 989.9719416 2683.10465 2231.955589 1.075995445 0.802284361 0.63117004 0.97696389 0.40015204 0.749849309 0.574977363 0.443544641 1.202131737 1 11.12409261 -6.53121184 0.759466295 1.041999762 0.554512202 0.634570363 0.157143485 0.281730887 0.32539345 0.030433203 0.059600177 2.94E-07 6.53121184 -0.48748756 NLFNVVDCK ddPTM_HeLa_Curcumin_4h_R1 1 NLFNVVDCK 9 0 P55884-2;P55884 P55884-2 EIF3B Eukaryotic translation initiation factor 3 subunit B 0 0 117.31 0.0015576 1514600 1424.3 1222.1 1238.4 1445.7 1564.5 1701.3 1236.1 1024.1 1622.9 1212.5 FALSE FALSE TRUE 1311.565152 1327.732878 1284.296193 1439.718076 1545.844359 1348.431202 1270.781639 1336.343376 1444.87193 1254.634285 1.045376464 1.05826287 1.023641876 1.147520113 1.232107538 1.074760365 1.012870168 1.065125823 1.151627967 1 10.29305118 -6.281200518 23.20153477 1.025471661 1.106493891 0.03751653 0.068545393 312.3989347 366786.4408 0.00945981 0.014466147 5.23E-07 6.281200518 0.08102223 NLGSGS(ph)PKPR ddPTM_HeLa_Curcumin_4h_R1 1 NLGSGSPKPR 10 1 A0A1C7CYX9 A0A1C7CYX9 1 0 NLGS(0.019)GS(0.981)PKPR 76.868 0.015589 242320000 9974.3 8729.1 8076.2 9909.4 9461.9 10623 8626.9 6901.6 10535 8818.5 TRUE FALSE FALSE 9184.82363 9483.604508 8375.511077 9868.397528 9349.073022 8419.670054 8868.947596 9005.866069 9379.336857 9124.942219 1.006562388 1.039305705 0.91787004 1.08147507 1.024562435 0.92270941 0.971945617 0.986950476 1.027879041 1 13.15559971 -5.279224627 24.80268767 1.006661799 0.961676207 0.241647811 0.041981285 816.2558103 1138320.678 0.005503098 0.01232842 5.26E-06 5.279224627 -0.044985592 NLHYFNSDSFASHPNYPYSDEY ddPTM_HeLa_Curcumin_4h_R1 2 NLHYFNSDSFASHPNYPYSDEY 22 0 S4R3Z2;A0A0A0MSS8;P42330;P42330-2 S4R3Z2 AKR1C3 Aldo-keto reductase family 1 member C3 0 0 ; ; 114.9 7.05E-06 19557900 1743.79 1353.08 1072.53 989.28 1749.48 6304.3 2804.3 2331.27 2134.65 1423.24 FALSE FALSE TRUE 1605.767181 1470.034206 1112.278905 985.1866215 1728.618594 4996.717116 2882.981111 3042.063491 1900.484236 1472.697484 1.090357795 0.998191565 0.755266385 0.66896741 1.173777108 3.392901237 1.957619363 2.065640448 1.290478361 1 10.52424539 -5.408063566 7.501402712 0.990024777 2.415826534 0.747828753 0.393514113 0.092843945 5.500646545 0.051380495 0.115270688 3.91E-06 5.408063566 1.425801757 NLIDAGVDALR ddPTM_HeLa_Curcumin_4h_R1 1 NLIDAGVDALR 11 0 P12268;H0Y4R1 P12268 IMPDH2 Inosine-5-monophosphate dehydrogenase 2 0 0 113.69 0.0033882 1566400 538.29 930.09 746.3 725.95 957.08 894.31 758.84 871.8 712.1 1004.4 FALSE FALSE TRUE 495.6837785 1010.482835 773.9585345 722.9462113 945.6674461 708.820025 780.1310081 1137.607807 633.9844116 1039.302825 0.476938739 0.972269882 0.744690109 0.695606895 0.909905586 0.682014912 0.750629161 1.094587428 0.610009322 1 10.02140036 -4.259936206 23.81607411 0.764245568 1.094587632 0.296446259 0.154417006 86.09152546 1363743.704 0.027106516 0.227943341 5.50E-05 4.259936206 0.330342064 NLILVVR ddPTM_HeLa_Curcumin_4h_R1 1 NLILVVR 7 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 118.69 0.0096686 7716900 3159.1 2685.3 2841.8 2363.8 2745 4175.6 3206.8 2673.6 2636.9 2300.5 FALSE FALSE TRUE 2909.053902 2917.405367 2947.119608 2354.019222 2712.267668 3309.533491 3296.774177 3488.768332 2347.638667 2380.442204 1.222064496 1.225572863 1.238055519 0.988899969 1.139396564 1.390301972 1.384941912 1.465596739 0.986219562 1 11.21701389 -1 0.216102479 1.054829303 3.17427036 0.633080133 0.100873038 29.20278559 0.346820738 0.089444344 21.66149628 0.1 1 2.119441056 NLLEDDS(ph)DEEEDFFLR ddPTM_HeLa_Curcumin_4h_R1 2 NLLEDDSDEEEDFFLR 16 0 O75379 O75379 VAMP4 Vesicle-associated membrane protein 4 1 0 NLLEDDS(1)DEEEDFFLR;NLLEDDS(1)DEEEDFFLR ; 170.61 0.00011885 14135000 2958.72 2395.75 3026.37 3537.4 2826.09 3566.2 2066.63 1185.25 3660.4 3106.8 TRUE FALSE FALSE 2724.53419 2602.827955 3138.529934 3522.763176 2792.390723 2826.529921 2124.614076 1546.627269 3258.863278 3214.761069 0.847507523 0.80964896 0.976287154 1.095808709 0.868615323 0.879234836 0.660893308 0.481101779 1.013718658 1 11.6504958 -4.561055115 1.715279951 0.930704476 0.44105601 0.777620636 0.081486762 0.210673166 0.910563507 0.012958901 0.139210201 2.75E-05 4.561055115 -0.489648467 NLLEENFEEHS(ph)MSPER ddPTM_HeLa_Curcumin_4h_R1 1 NLLEENFEEHSMSPER 16 0 P38398-8;P38398-4;P38398;P38398-7;Q5YLB2 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 0 NLLEENFEEHS(0.757)MS(0.243)PER 133.24 0.00020967 6536300 3535.7 3273.7 3201.3 3516.1 3782.1 3678.1 2947.2 1442.3 3205.5 3039.2 TRUE FALSE FALSE 3255.845614 3556.664041 3319.942994 3501.55131 3737.000928 2915.220599 3029.8905 1882.05063 2853.86467 3144.811974 1.035306925 1.130962382 1.055688868 1.113437413 1.188306633 0.926993608 0.963456806 0.598462053 0.907483402 1 11.61875805 -3.986739191 1.49664697 1.043846165 0.131860265 0.733349889 0.080932912 0.823018309 0.989833396 0.010628839 1.348958159 0.000103101 3.986739191 -0.911985901 NLLSVAYK ddPTM_HeLa_Curcumin_4h_R1 2 NLLSVAYK 8 0 P27348;E9PG15;P31946-2;P31946;Q4VY20;Q4VY19;A0A0J9YWE8;A0A0J9YWZ2;A2IDB2;P63104;E7EX29;E7ESK7;E5RIR4;E9PD24;E7EVZ2;E5RGE1;P62258;P62258-2;B4DJF2;I3L3T1;K7EIT4;P31947-2;P31947;P61981;Q04917 P27348;P31946-2;P63104;P62258;P31947-2;P61981;Q04917 YWHAQ;YWHAB;YWHAH;YWHAZ;YWHAE;SFN;YWHAG "14-3-3 protein theta;14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed;14-3-3 protein zeta/delta;14-3-3 protein epsilon;14-3-3 protein sigma;14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed;14-3-3 protein eta" 0 0 ; ; 124.23 0.0022675 26529000 12322.3 8453.8 10571.3 8381.8 10930.4 12720 12047.7 10986.6 10084.8 10200.7 FALSE FALSE TRUE 11346.97695 9184.508803 10963.08168 8347.118332 10800.06212 10081.72862 12385.72604 14336.36376 8978.522671 10555.17357 1.075015667 0.870142849 1.038645325 0.79080825 1.023200808 0.955145697 1.173427037 1.358230983 0.850627668 1 13.36566268 -4.481886528 2.795621993 1.001969971 1.359881133 0.614990562 0.097948128 0.15290069 2.075156132 0.012514626 0.097585673 3.30E-05 4.481886528 0.357911162 NLLSVAYK(ac)NVVGAR ddPTM_HeLa_Curcumin_4h_R1 1 NLLSVAYKNVVGAR 14 1 P31946-2;P31946;Q4VY20;Q4VY19;A0A0J9YWE8;A0A0J9YWZ2;A2IDB2;P63104;E7EX29;E7ESK7;E5RIR4;E9PD24;E7EVZ2;P61981;Q04917 P31946-2;P63104;P61981;Q04917 YWHAB;YWHAH;YWHAZ;YWHAG "14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed;14-3-3 protein zeta/delta;14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed;14-3-3 protein eta" 0 1 NLLSVAYK(1)NVVGAR 119.69 8.74E-06 0 57.87 0 57.492 0 0 0 0 0 0 0 FALSE TRUE FALSE 53.28952844 0 59.6227041 0 0 0 0 0 0 0 0 NLNNS(ph)NLFSPVNR ddPTM_HeLa_Curcumin_4h_R1 1 NLNNSNLFSPVNR 13 0 A0A3B3ITD8;P52948-6;P52948-2;P52948-5;P52948;P52948-4;P52948-3;H0YEN4 A0A3B3ITD8 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 0 NLNNS(0.997)NLFS(0.003)PVNR 130.66 0.0016083 16187000 891.69 644.06 792.99 857.13 828.54 893.78 680.54 472.54 976.11 941.53 TRUE FALSE FALSE 821.1117956 699.7296765 822.378907 853.5834232 818.6602016 708.399953 699.6341208 616.6152707 869.0331751 974.2480974 0.842815909 0.718225346 0.844116513 0.876145846 0.840299513 0.7271248 0.718127264 0.632914011 0.892003975 1 9.928145399 -9.360378296 0.042131007 1.877122661 1.04E-11 0.598211941 0.065088959 75.07258195 0.772340233 20.63489859 14.07722069 4.36E-10 9.360378296 -1.877122661 RVVLGDGVQLPPGDYSTT(ph)PGGTLFSTTPGGTR ddPTM_HeLa_Curcumin_4h_R1 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 1 0 RVVLGDGVQLPPGDY(0.073)S(0.079)T(0.079)T(0.379)PGGT(0.318)LFS(0.02)T(0.02)T(0.02)PGGT(0.009)R 61.112 0.00042404 27389000 745.31 402.04 565.55 635.26 360.3 918.96 612.25 966.54 853.02 554.58 TRUE FALSE FALSE 686.3179271 436.7905461 586.5097805 632.6314624 356.0036578 728.3573372 629.4280872 1261.233597 759.4458402 573.8516137 1.195985008 0.761155908 1.022058258 1.102430397 0.620375807 1.269243337 1.096848161 2.197839244 1.323418497 1 9.164533923 -4.248745918 4.056537182 1.045392414 2.312220878 0.741588578 0.204555315 0.088658221 3.016273786 0.025419492 0.331658223 5.64E-05 4.248745918 1.266828464 up NLPLPPPPPPR ddPTM_HeLa_Curcumin_4h_R1 1 NLPLPPPPPPR 11 0 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 0 108.98 0.0049309 4259100 1506.1 1392.1 1293.4 1568.3 1479.8 1606.7 1468.2 1104.7 2049.5 1387.9 FALSE FALSE TRUE 1386.890596 1512.426921 1341.334542 1561.81079 1462.154351 1273.452309 1509.393741 1441.517945 1824.674978 1436.129422 0.965714214 1.053127175 0.933992801 1.087513957 1.018121577 0.886725311 1.051015123 1.003752115 1.270550516 1 10.48797005 NLQAPSK(ac)LTNSSSTGTVGK ddPTM_HeLa_Curcumin_4h_R1 1 NLQAPSKLTNSSSTGTVGK 19 1 Q6ZU65 Q6ZU65 UBN2 Ubinuclein-2 0 1 NLQAPSK(1)LTNSSSTGTVGK 287.43 2.36E-112 2926700 942.21 887.44 726.99 754.03 867.54 1201.8 1177.3 153.24 1017.8 1139.2 FALSE TRUE FALSE 867.6330843 964.1463592 753.9328889 750.9100237 857.1951521 952.5331329 1210.331869 199.9621706 906.1498864 1178.787115 0.736038826 0.817913894 0.639583585 0.637019199 0.727184019 0.80806205 1.026760349 0.169633828 0.768713769 1 10.20308748 -13.52287874 0.167342605 2.193748829 0.628389929 0.090260886 0.214778789 61.22825413 0.672709571 23.75410712 0.32202634 3.00E-14 13.52287874 -1.565358899 NLQDGQISDTGDLGEDIAS(ph)N ddPTM_HeLa_Curcumin_4h_R1 2 NLQDGQISDTGDLGEDIASN 20 0 A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YHT2;Q7Z4S6-3;H0YI78 A0A1B0GV47 KIF21A Kinesin-like protein KIF21A 1 0 NLQDGQISDTGDLGEDIAS(1)N;NLQDGQISDTGDLGEDIAS(1)N ; 190.25 3.28E-10 17544800 9235.7 7368.5 8203.5 9203.5 8373.2 9838 6786.4 3989.4 8883.8 7890.8 TRUE FALSE FALSE 8504.6846 8005.400307 8507.528927 9165.418356 8273.355059 7797.487903 6976.808119 5205.749695 7909.269366 8165.004713 1.041601922 0.980452625 1.041950278 1.122524564 1.01327009 0.954988782 0.854476925 0.637568486 0.968679094 1 12.995238 -4.318306645 1.344139404 1.026047445 0.499021164 0.895081397 0.040948673 0.248911159 0.417807758 0.005821391 0.172865382 4.80E-05 4.318306645 -0.527026281 NLQEAEEWYK ddPTM_HeLa_Curcumin_4h_R1 4 NLQEAEEWYK 10 0 P08670;B0YJC4;B0YJC5;H7C5W5;P41219;P41219-2;F8W835 P08670 VIM;PRPH Vimentin;Peripherin 0 0 ;;; ;;; 206.48 1.72E-26 351985200 15551.4 11871.6 14250.5 14378.9 12994.09 15448 13684.65 11690.16 13669.07 10143.5 FALSE FALSE TRUE 14320.49028 12897.72821 14778.63607 14319.40392 12839.14396 12243.91067 14068.60445 15254.43597 12169.60722 10495.98587 1.364377816 1.228824845 1.408027435 1.364274314 1.223243259 1.166532693 1.340379515 1.453359042 1.159453468 1 13.35755006 -9.307888432 0.830742891 0.981326044 1.31666739 0.463485298 0.096930281 0.354858345 0.399465294 0.079068513 0.017016818 4.92E-10 9.307888432 0.335341345 NLQEEIDALESR ddPTM_HeLa_Curcumin_4h_R1 3 NLQEEIDALESR 12 0 Q9NQP4;E9PQY2 Q9NQP4 PFDN4 Prefoldin subunit 4 0 0 ;; ;; 171.32 0.0011336 8924000 5364.2 4602.26 4927.4 4995.3 5308.6 5641 4768.68 4725.78 5759.1 5096.3 FALSE FALSE TRUE 4939.61791 5000.058847 5110.013779 4974.630772 5245.298412 4470.993013 4902.476327 6166.648567 5127.341139 5273.396046 0.936705278 0.948166761 0.969017638 0.943344806 0.994671814 0.847839414 0.929662078 1.169388476 0.972303444 1 12.36451664 -4.256789706 24.88601154 0.957697382 1.169388568 0.715655937 0.041340485 209.3823721 1120615.577 0.006198377 0.066978455 5.54E-05 4.256789706 0.211691186 NLQEVLGEEK ddPTM_HeLa_Curcumin_4h_R1 2 NLQEVLGEEK 10 0 P54577;A0A0C4DGZ5 P54577 YARS "Tyrosine--tRNA ligase, cytoplasmic;Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed;Tyrosine--tRNA ligase" 0 0 ; ; 146.11 1.24E-05 3308900 3114.4 2475.8 2318.8 2987.4 2570.4 3085.7 2285.3 2141.2 2692 2467 FALSE FALSE TRUE 2867.891954 2689.79712 2404.736768 2975.03893 2539.749659 2445.691037 2349.419367 2794.042023 2396.694335 2552.728066 1.123461598 1.053695125 0.942026219 1.165435116 0.994915868 0.958069553 0.920356304 1.094531791 0.938875694 1 11.31782415 -5.551163703 24.9998355 1.057237015 0.982684447 0.035284024 0.079790096 268.1318571 236989.2113 0.010738582 0.021477418 2.81E-06 5.551163703 -0.074552568 NLQLLTQASS(ph)EGSP ddPTM_HeLa_Curcumin_4h_R1 1 NLQLLTQASSEGSP 14 0 B8ZZB7;H0YEJ0 B8ZZB7 SAMD12 1 0 NLQLLT(0.001)QAS(0.027)S(0.621)EGS(0.352)P 80.96 0.018224 3319700 1091.5 1071.7 934.2 1269.6 848.42 1300.6 942.05 1033.4 1207.7 982.01 TRUE FALSE FALSE 1005.106623 1164.332973 968.8222738 1264.346732 838.3031456 1030.840899 968.4813876 1348.478903 1075.218332 1016.134774 0.98914696 1.145845022 0.953438755 1.244270704 0.824992084 1.014472612 0.953103281 1.327066977 1.058145394 1 9.98887605 -4.255524929 24.74741064 1.00660053 1.327067138 0.413564821 0.108449501 369.8482658 1547477.734 0.013141054 0.158694561 5.55E-05 4.255524929 0.320466608 NLQYYDISAK ddPTM_HeLa_Curcumin_4h_R1 2 NLQYYDISAK 10 0 F5H018;B5MDF5;J3KQE5;P62826;B4DV51 F5H018 RAN GTP-binding nuclear protein Ran 0 0 ; ; 196.27 1.91E-20 28085000 10972.2 9345.4 9550.2 9051.7 9693.2 12168.7 9689 10053.3 9822.4 8642.7 FALSE FALSE TRUE 10103.73879 10153.17473 9904.138813 9014.246464 9577.614921 9644.77445 9960.847263 13118.50489 8744.907294 8943.033182 1.129788807 1.135316679 1.10746976 1.00796299 1.070958223 1.078467926 1.113810836 1.466896591 0.977845784 1 13.12654851 -4.248445101 3.237152282 1.069203472 1.529850655 0.844840176 0.051496026 0.112411994 1.809437214 0.007954232 0.131591858 5.64E-05 4.248445101 0.460647184 NLRDIDEVSSLLR ddPTM_HeLa_Curcumin_4h_R1 2 NLRDIDEVSSLLR 13 1 P50990-2;P50990;P50990-3;H7C4C8 P50990-2 CCT8 T-complex protein 1 subunit theta 0 0 ; ; 130.19 0.0014141 17207000 4597 3735.1 3618 4822 2972.3 5002.1 3646.8 3553 5601.2 5796.6 FALSE FALSE TRUE 4233.142599 4057.945401 3752.086263 4802.047842 2936.857264 3964.608075 3749.119393 4636.293344 4986.762374 5998.031419 0.705755323 0.676546206 0.625552952 0.800603983 0.489636859 0.66098488 0.625058312 0.772969166 0.831399842 1 12.55027336 -8.976444518 0.516231518 1.045352699 0.650494142 0.487427572 0.095162279 0.480079424 0.207000012 0.092439094 0.020696961 1.06E-09 8.976444518 -0.394858557 NLS(ph)FNELYPSGTLK ddPTM_HeLa_Curcumin_4h_R1 1 NLSFNELYPSGTLK 14 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 0 NLS(0.999)FNELYPS(0.001)GTLK 157.07 0.00036015 70652000 6526.1 4456.2 5629.5 6382.4 5853.2 7261.8 6152.1 2065.1 7161.4 5776.4 TRUE FALSE FALSE 6009.552299 4841.374072 5838.134222 6355.99132 5783.404413 5755.620823 6324.711368 2694.739483 6375.812337 5977.12947 1.005424482 0.809983136 0.976745485 1.063385251 0.967588947 0.962940631 1.058151977 0.450841746 1.066701394 1 12.54523708 -4.257016892 24.99687815 0.989911176 0.45084153 0.839418428 0.070758445 118.7263146 671042.8456 0.008977175 0.09509533 5.53E-05 4.257016892 -0.539069645 IMVGS(ph)TDDPSVFSLPDSK ddPTM_HeLa_Curcumin_4h_R1 2 IMVGSTDDPSVFSLPDSK 18 0 O43741 O43741 PRKAB2 5-AMP-activated protein kinase subunit beta-2 1 0 IMVGS(0.912)T(0.088)DDPSVFSLPDSK;IMVGS(0.822)T(0.171)DDPS(0.007)VFSLPDSK ; 202.41 4.92E-12 28775000 4617.7 3301.6 3531.9 3999.5 3770.4 4440.1 2468.9 939.32 3456.7 3834 TRUE FALSE FALSE 4252.204172 3586.975592 3662.795321 3982.951129 3725.440443 3519.17321 2538.170689 1225.714344 3077.508658 3967.231215 1.071831699 0.90415088 0.923262377 1.00396244 0.939053017 0.887060274 0.639783908 0.308959644 0.775732114 1 11.95391677 -4.311929228 1.052347451 1.013859768 7.12E-16 0.821148814 0.090232659 0.281905131 0.257745933 0.008952858 0.312384738 4.88E-05 4.311929228 -1.013859768 down NLS(ph)KLSMLSIR ddPTM_HeLa_Curcumin_4h_R1 1 NLSKLSMLSIR 11 1 X6RI37;Q9UQ13-2;Q9UQ13 X6RI37 SHOC2 Leucine-rich repeat protein SHOC-2 1 0 NLS(0.5)KLS(0.5)MLSIR 75.387 0.014591 10160000 1328.8 1078.7 1232 1246.4 1042 1514.6 1360.3 1282 1190.6 998.85 TRUE FALSE FALSE 1223.624078 1171.938021 1277.659004 1241.242727 1029.574831 1200.454887 1398.466357 1672.875898 1059.994159 1033.559963 1.183892683 1.133884886 1.236173081 1.20093925 0.996144266 1.161475802 1.353057787 1.618557179 1.02557587 1 10.01340638 -4.460230777 1.877927825 1.106269076 1.675732257 0.798749122 0.079898738 0.205596792 0.999598134 0.013609615 0.177013045 3.47E-05 4.460230777 0.569463181 NLS(ph)LVSS(ph)S(ph)S(ph)RGNT(ph)STLRR ddPTM_HeLa_Curcumin_4h_R1 1 NLSLVSSSSRGNTSTLRR 18 2 Q8TEC5 Q8TEC5 SH3RF2 Putative E3 ubiquitin-protein ligase SH3RF2 5 0 NLS(0.961)LVS(0.049)S(0.691)S(0.691)S(0.691)RGNT(0.668)S(0.64)T(0.608)LRR 49.141 0.0094979 0 1169.1 1122.3 942.38 1061.6 1191.3 1263.1 1208.1 1060.9 1203.4 1038.9 TRUE FALSE FALSE 1076.564501 1219.306611 977.3054318 1057.20738 1177.094526 1001.118822 1241.996035 1384.363526 1071.390031 1075.001698 1.001453769 1.134236917 0.909119896 0.983447173 1.094969922 0.931271852 1.155343324 1.287777991 0.996640315 1 10.07012322 -4.536199546 3.83394292 1.005633955 1.269879804 0.665004543 0.064145605 0.083686095 2.631914437 0.008135606 0.042511394 2.91E-05 4.536199546 0.264245849 VDIDT(ph)PDIDIHGPEGK ddPTM_HeLa_Curcumin_4h_R1 2 VDIDTPDIDIHGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VDIDT(1)PDIDIHGPEGK;VDIDT(1)PDIDIHGPEGK ; 173.03 0.00022556 313913000 8235.7 6096.8 8802.2 8852 8042.6 8505.4 10883 16370.4 6224.5 5252.5 TRUE FALSE FALSE 7583.835655 6623.780225 9128.417275 8815.372769 7946.697248 6741.284164 11188.34769 21361.6596 5541.687923 5435.023984 1.395363788 1.218721434 1.679554184 1.621956554 1.462127356 1.240341199 2.058564548 3.930370807 1.019625293 1 12.40807069 -4.248545892 1.953821798 1.277104853 4.800499448 0.925613967 0.222258938 0.167904346 0.648870489 0.036986411 1.07332982 5.64E-05 4.248545892 3.523394595 up NLS(ph)PGAVESDVR ddPTM_HeLa_Curcumin_4h_R1 4 NLSPGAVESDVR 12 0 A0A3B3ISK1;A0A3B3ITV3;A0A3B3ISC6;A0A3B3IT15;A0A3B3IS84;P53621;P53621-2;A0A3B3IU78 A0A3B3ISK1 COPA Coatomer subunit alpha;Xenin;Proxenin 1 0 NLS(1)PGAVESDVR;NLS(1)PGAVESDVR;NLS(1)PGAVESDVR;NLS(1)PGAVESDVR ;;; 178.47 0.00011859 396799000 11230.5 9671.4 10212 10924.3 10178.5 11606 9478.9 10077.9 11555.6 11101.3 TRUE FALSE FALSE 10341.59407 10507.35272 10590.4657 10879.09814 10057.12804 9198.784773 9744.852423 13150.60532 10287.97959 11487.06935 0.90028133 0.914711351 0.921946702 0.947073428 0.875517308 0.800794745 0.84833234 1.144818136 0.895613953 1 13.48772316 -9.283053896 0.80569272 1.005473729 0.911315708 0 0.091567642 1.230797489 1.300730812 0.075301381 0.016293212 5.21E-10 9.283053896 -0.094158021 APS(ph)APPGTGALPPAAPSGR ddPTM_HeLa_Curcumin_4h_R1 1 APSAPPGTGALPPAAPSGR 19 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 0 APS(0.995)APPGT(0.005)GALPPAAPSGR 106.87 0.00061066 14947000 2445.4 1740.4 2175.6 2104.7 1984.6 2244.1 1381.4 593.11 1946.2 1755.6 TRUE FALSE FALSE 2251.84401 1890.832421 2256.22965 2095.991309 1960.934941 1778.648364 1420.158366 773.9465087 1732.706729 1816.606969 1.239587895 1.040859389 1.242002088 1.153794599 1.079449201 0.979104668 0.78176424 0.426039601 0.953814864 1 10.8270306 -4.309834877 1.168146399 1.122876385 0.132840946 0.84622001 0.089951239 0.414542573 0.486658324 0.014609663 0.48771842 4.90E-05 4.309834877 -0.990035439 down NLSEGNNANYTEY(ph)VATR ddPTM_HeLa_Curcumin_4h_R1 1 NLSEGNNANYTEYVATR 17 0 A0A1B0GTX4;A0A096LNR9;A0A1B0GUM4;A0A669KBC2;O76039;O76039-1 A0A1B0GTX4 CDKL5 Cyclin-dependent kinase-like 5 1 0 NLSEGNNANY(0.001)T(0.03)EY(0.967)VAT(0.002)R 131.61 0.0021365 6870200 1133.9 1396.4 1293 1098.4 1080.8 1477.1 1108.8 610.37 1668.4 1739.6 TRUE FALSE FALSE 1044.150619 1517.098594 1340.919717 1093.855112 1067.912166 1170.73281 1139.909944 796.4690032 1485.380694 1800.050971 0.580067251 0.842808686 0.744934304 0.607680077 0.593267737 0.650388699 0.63326537 0.44247025 0.82518813 1 10.81382204 -13.52287875 0.234642075 3.124427809 0.585047819 0.509174567 0.107394104 20.78270187 0.26955485 20.37263876 0.068297865 3.00E-14 13.52287875 -2.53937999 NLSFNELY(ph)PSGTLK ddPTM_HeLa_Curcumin_4h_R1 1 NLSFNELYPSGTLK 14 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 0 NLSFNELY(0.813)PS(0.186)GT(0.001)LK 154.15 0.0025974 70982000 5720.3 4384.3 5082.4 5633.7 4781.9 7060.8 5497 1663.2 6820.4 5449.2 TRUE FALSE FALSE 5267.532219 4763.259356 5270.758215 5610.389242 4724.878966 5596.310488 5651.231026 2170.302024 6072.219184 5638.559294 0.934198249 0.844765322 0.93477038 0.995004034 0.837958549 0.992507163 1.002247335 0.384903645 1.076909697 1 12.46111087 -4.258488082 24.98932074 0.954038875 0.384903437 0.85790415 0.069908486 63.49032293 537558.7786 0.008333582 0.078125458 5.51E-05 4.258488082 -0.569135438 NLSLS(ph)SSTPPLPSPGR ddPTM_HeLa_Curcumin_4h_R1 1 NLSLSSSTPPLPSPGR 16 0 E9PB87;O43516-2;O43516;O43516-3 E9PB87 WIPF1 WAS/WASL-interacting protein family member 1 1 0 NLSLS(0.303)S(0.303)S(0.303)T(0.085)PPLPS(0.007)PGR 118.2 0.0010503 5841200 1646.4 1085.1 1218.4 1385.8 1416.8 1718.6 1047.7 577.94 1473.1 1279.1 TRUE FALSE FALSE 1516.085703 1178.891209 1263.554976 1380.065927 1399.905585 1362.142987 1077.095642 754.1512455 1311.504616 1323.54863 1.145470343 0.890704869 0.95467212 1.042701338 1.057691084 1.029159758 0.81379378 0.56979489 0.99090021 1 10.37019549 -4.451549062 1.936619016 1.04606274 0.515423104 0.793703727 0.069698656 0.184839189 0.962740734 0.011767041 0.151775136 3.54E-05 4.451549062 -0.530639636 NLSLSSSTPPLPS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 1 NLSLSSSTPPLPSPGR 16 0 E9PB87;O43516-2;O43516;O43516-3 E9PB87 WIPF1 WAS/WASL-interacting protein family member 1 1 0 NLSLSS(0.005)S(0.008)T(0.013)PPLPS(0.975)PGR 105.01 0.0030351 0 846.86 615.36 477.33 613.38 701.04 1052 926.81 603.9 828.82 493.61 TRUE FALSE FALSE 779.8301374 668.5489764 495.0202697 610.8419961 692.6805559 833.8033415 952.8137942 788.02633 737.9005196 510.7629108 1.526794763 1.308922324 0.969178183 1.195940393 1.356168471 1.632466501 1.865471776 1.542841724 1.444702628 1 8.996509957 -1 0.040453462 1.70E-10 3.743722363 0.22347821 0.23383772 588.8038597 1.832013591 46.64800519 151.3849339 0.1 1 3.743722363 NLSLTDFVGDES(ph)PSPERLK ddPTM_HeLa_Curcumin_4h_R1 1 NLSLTDFVGDESPSPERLK 19 1 E9PDC2;A0A088AWP5;Q8WUY3-4;Q8WUY3;Q8WUY3-2;Q8WUY3-3 E9PDC2 PRUNE2 Protein prune homolog 2 1 0 NLSLTDFVGDES(0.876)PS(0.124)PERLK 81.38 0.001818 26149000 1177.3 793.46 607.3 929.88 776.94 854.65 657.78 799.5 1117.6 1092.2 TRUE FALSE FALSE 1084.115463 862.0431468 629.8070722 926.0324029 767.6754979 677.3859561 676.2355365 1043.26387 995.0020761 1130.153869 0.959263595 0.762766178 0.557275509 0.819386128 0.679266354 0.599374983 0.598357051 0.923116664 0.880412928 1 10.14230349 -7.208594816 3.354538065 0.982493015 0.690190265 0.508578894 0.108210524 0.110112202 2.478523766 0.016690653 0.020216587 6.19E-08 7.208594816 -0.292302749 NLSLTDFVGDESPS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 2 NLSLTDFVGDESPSPER 17 0 E9PDC2;A0A088AWP5;Q8WUY3-4;Q8WUY3;Q8WUY3-2;Q8WUY3-3 E9PDC2 PRUNE2 Protein prune homolog 2 1 0 NLSLTDFVGDESPS(1)PER;NLSLTDFVGDES(0.001)PS(0.999)PER ; 180.03 8.27E-06 58429000 6111.5 5517.9 6182.5 6543.3 6125 6836.3 5077.6 4461.7 6171.8 5227.1 TRUE FALSE FALSE 5627.768326 5994.842689 6411.628889 6516.225558 6051.963375 5418.374319 5220.06379 5822.051791 5494.768981 5408.741336 1.040495002 1.108361875 1.185419766 1.204758215 1.118922685 1.001781003 0.965116183 1.076415275 1.015905298 1 12.40107719 -3.246164207 13.98251403 1.051493667 1.071845709 0 0.079874585 0 0 0.012031323 0 0.00056733 3.246164207 0.020352042 NLSLTDFVGDESPS(ph)PERLK ddPTM_HeLa_Curcumin_4h_R1 3 NLSLTDFVGDESPSPERLK 19 1 E9PDC2;A0A088AWP5;Q8WUY3-4;Q8WUY3;Q8WUY3-2;Q8WUY3-3 E9PDC2 PRUNE2 Protein prune homolog 2 1 0 NLSLTDFVGDES(0.007)PS(0.993)PERLK;NLSLTDFVGDES(0.042)PS(0.958)PERLK;NLSLTDFVGDES(0.138)PS(0.862)PERLK ;; 80.835 0.0018777 50140700 3035 2712.34 2489.42 2421.43 2502.64 3602.6 2314.09 2766.94 3575.23 3140.61 TRUE FALSE FALSE 2794.776547 2946.782584 2581.680095 2411.410764 2472.797653 2855.38015 2379.017137 3610.567269 3183.036214 3249.745964 0.859998467 0.906773211 0.794425202 0.742030544 0.760920294 0.878647187 0.732062495 1.111030619 0.979472319 1 11.66611123 -8.7793456 0.617542322 1.004760202 0.833924272 0.222725638 0.104722363 0.871272385 0.618363315 0.075912426 0.023940565 1.66E-09 8.7793456 -0.170835931 NLSNEELT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 NLSNEELTK 9 0 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 0 NLSNEELT(1)K 152.69 0.0043139 115180000 3859 2881.1 3183.7 3398.3 3587 4095.1 3584.2 6048.9 3706.8 3761.4 TRUE FALSE FALSE 3553.556078 3130.129446 3301.690723 3384.238735 3544.227368 3245.730099 3684.763006 7893.181764 3300.173314 3892.10837 0.913015708 0.804224638 0.848303903 0.869512977 0.910618881 0.833925932 0.946726724 2.0279964 0.847914035 1 11.92633617 -4.261736255 6.435482852 0.921551715 2.050858384 0.965709585 0.0642605 0.017924438 4.334831133 0.010551506 0.087942202 5.47E-05 4.261736255 1.129306669 NLSPS(ph)FSR ddPTM_HeLa_Curcumin_4h_R1 1 NLSPSFSR 8 0 Q1ED39;H3BNU8 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 1 0 NLS(0.078)PS(0.881)FS(0.04)R 106.62 0.012283 7102600 2873.6 2880 2458.4 2436 3121.3 4281 3971.5 2062.4 3184.6 2071.3 TRUE FALSE FALSE 2646.151528 3128.934367 2549.510467 2425.920477 3084.080536 3393.072343 4082.929601 2691.216266 2835.257347 2143.277521 1.234628508 1.459882977 1.189538192 1.131874176 1.438955294 1.583123189 1.904993433 1.255654594 1.322860581 1 11.06560295 -5.287735647 0.163810653 0.875744754 2.051111904 0.226502115 0.215623348 8.103994201 0.354240069 0.558277714 2.234564053 5.16E-06 5.287735647 1.17536715 NLSS(ph)DEATNPISR ddPTM_HeLa_Curcumin_4h_R1 1 NLSSDEATNPISR 13 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 NLS(0.289)S(0.705)DEAT(0.006)NPISR 163.9 0.00017629 72659000 1389.8 1309.7 1197.5 1386.6 1203.5 1432.9 1009.5 655 1307.5 1130.9 TRUE FALSE FALSE 1279.795863 1422.904632 1241.880403 1380.862617 1189.149049 1135.700388 1037.823853 854.7064848 1164.070521 1170.198691 1.093656892 1.215951311 1.061256018 1.180024066 1.016194137 0.970519277 0.886878323 0.730394327 0.994763138 1 10.19253779 -4.524439047 1.24061918 1.068815702 0.669412021 0.727091398 0.069299336 0.422391822 0.749894764 0.011267999 0.189755994 2.99E-05 4.524439047 -0.39940368 NLT(ph)EDNSQNQDLIAK ddPTM_HeLa_Curcumin_4h_R1 1 NLTEDNSQNQDLIAK 15 0 Q9UBB4-2;Q9UBB4;B1AHE3 Q9UBB4-2 ATXN10 Ataxin-10 1 0 NLT(0.705)EDNS(0.295)QNQDLIAK 92.112 0.019323 5611000 1183.9 1162.6 1389.5 1178.5 1228.3 1299.3 1098.1 1228.3 1427.5 1476 TRUE FALSE FALSE 1090.193066 1263.089964 1440.996092 1173.623679 1213.653325 1029.810534 1128.909731 1602.803016 1270.906821 1527.29089 0.713808399 0.827013355 0.943498126 0.768434937 0.794644512 0.674272688 0.739158295 1.049441875 0.832131475 1 10.57675915 -9.48887831 1.204997691 1.001106043 0.799064159 0.027522811 0.11702076 0.446535721 1.149992811 0.075278576 0.017944934 3.24E-10 9.48887831 -0.202041884 NLTANDPSQEYVAS(ph)EGEEDPEVEFLK ddPTM_HeLa_Curcumin_4h_R1 3 NLTANDPSQEYVASEGEEDPEVEFLK 26 0 Q86X95 Q86X95 CIR1 Corepressor interacting with RBPJ 1 1 0 NLTANDPSQEY(0.014)VAS(0.986)EGEEDPEVEFLK;NLTANDPSQEYVAS(1)EGEEDPEVEFLK;NLTANDPSQEY(0.108)VAS(0.892)EGEEDPEVEFLK ;; 151.66 3.31E-09 111533100 16974.4 14783.1 15896.8 16583.8 15652.9 19337.6 15611.8 13150.18 18025.5 15355.2 TRUE FALSE FALSE 15630.85833 16060.88529 16485.94939 16515.18063 15466.24939 15326.76378 16049.82509 17159.60935 16048.14775 15888.79206 0.98376631 1.010831109 1.037583558 1.039423297 0.973406244 0.964627375 1.010135008 1.079981995 1.01002944 1 13.95572183 -7.153626669 6.143977193 0.992367898 1.014550505 0.057712134 0.031754678 0.454847858 22.45345423 0.005402635 0.006633496 7.02E-08 7.153626669 0.022182607 NLVDNITGQR ddPTM_HeLa_Curcumin_4h_R1 2 NLVDNITGQR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 133.81 2.60E-11 5881900 2925.6 2583.1 2790.7 2713.73 2529 3326.3 2507.3 2431.4 2993.8 2590.1 FALSE FALSE TRUE 2694.035673 2806.371654 2894.125797 2702.501304 2498.843327 2636.387885 2577.64809 3172.722667 2665.38763 2680.105782 1.005197515 1.047112272 1.079855062 1.008356208 0.932367425 0.983687996 0.961771027 1.183805016 0.994508369 1 11.38807423 -6.941324049 0.003961914 3.24E-08 2.027778364 0.04086599 0.065654579 30115.55697 83.32434882 21237.75872 21405.87565 1.14E-07 6.941324049 2.027778332 NLVPGESVYGEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 NLVPGESVYGEKR 13 1 M0R0P1;M0R299;M0QXL5;M0R2Q4;P22087;M0R2U2;M0R1H0;M0R2B0 M0R0P1 FBL rRNA 2-O-methyltransferase fibrillarin 0 1 ; NLVPGESVYGEK(1)R;NLVPGESVYGEK(1)R 105.65 0.0011072 4283400 1185.46 1461.02 1279.24 951.38 1101.81 1936.03 1171.57 1124.19 2015.62 1182.22 FALSE TRUE FALSE 1091.62959 1587.304059 1326.64976 947.4434416 1088.671635 1534.475554 1204.441101 1466.950356 1794.511529 1223.302057 0.892363079 1.297556928 1.084482571 0.774496729 0.889945071 1.25437176 0.984581931 1.199172639 1.466940662 1 10.25656496 -5.271626956 24.97360607 0.968432992 1.129896096 0 0.215003339 832.6024262 2041024.544 0.021417604 0.04840767 5.35E-06 5.271626956 0.161463105 NLVS(ph)PAYCTQESR ddPTM_HeLa_Curcumin_4h_R1 1 NLVSPAYCTQESR 13 0 Q9NUQ3 Q9NUQ3 TXLNG Gamma-taxilin 1 0 NLVS(0.841)PAYCT(0.135)QES(0.024)R 93.106 0.010578 41491000 2234.2 1860.7 2179.4 1605.2 1772.1 1808.1 1581.9 1055.5 2257.3 2085.6 TRUE FALSE FALSE 2057.360712 2021.530617 2260.170481 1598.558108 1750.968865 1433.079679 1626.283857 1377.317091 2009.679837 2158.074445 0.953331669 0.936728861 1.047308858 0.740733533 0.811357027 0.664054793 0.753580981 0.638215746 0.931237494 1 11.07552892 -6.24753336 21.67326686 0.978382083 0.725156467 0.842954903 0.054384375 35.61704442 55510.52799 0.007593765 0.012530218 5.66E-07 6.24753336 -0.253225616 RIPSIVSS(ph)PLNS(ph)PLDR ddPTM_HeLa_Curcumin_4h_R1 1 RIPSIVSSPLNSPLDR 16 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 2 0 RIPS(0.001)IVS(0.099)S(0.901)PLNS(1)PLDR 97.662 0.0014391 7715500 1166.8 1145.6 987.8 1146.2 1136.9 1382.1 1453.2 3124.7 1170.2 1027.4 TRUE FALSE FALSE 1074.446549 1244.620559 1024.408737 1141.457328 1123.34321 1095.436881 1493.972881 4077.406646 1041.831988 1063.102074 1.010671106 1.170744174 0.963603366 1.073704357 1.05666543 1.030415524 1.405295802 3.835385846 0.979992433 1 10.05406441 -4.248541542 3.019254973 1.02544529 4.338152174 0.995191642 0.058018575 0.018986784 0.246794465 0.008517922 0.152764055 5.64E-05 4.248541542 3.312706884 up NLVYDQS(ph)PNR ddPTM_HeLa_Curcumin_4h_R1 2 NLVYDQSPNR 10 0 I3L533;I3L2R9;Q9NXR1;Q9NXR1-1;I3L2T8 I3L533 NDE1 Nuclear distribution protein nudE homolog 1 1 0 NLVYDQS(1)PNR;NLVYDQS(1)PNR ; 138.2 0.0017591 82162000 6910.1 5346.9 5452.5 6088.8 5564.6 8326.4 7128.3 3577.5 5926 5431.2 TRUE FALSE FALSE 6363.158293 5809.062211 5654.574447 6063.606159 5498.245779 6599.410782 7328.300913 4668.263281 5275.932626 5619.933796 1.13224791 1.033653139 1.006163889 1.07894619 0.978347073 1.174286214 1.303983495 0.830661615 0.938789106 1 12.45633742 -9.610834498 1.417592762 1.000029002 1.081434731 0.071812546 0.121025834 1.038242891 3.747634441 0.079697561 0.018362416 2.45E-10 9.610834498 0.081405729 NLWVLVVGR ddPTM_HeLa_Curcumin_4h_R1 1 NLWVLVVGR 9 0 F8VVI6;F8W111;P14384 F8VVI6 CPM Carboxypeptidase M 0 0 73.26 0.019577 1692700 580.84 432.66 223.42 426.41 640.83 1253.7 497.32 456.74 688.93 370.29 FALSE FALSE TRUE 534.8659011 470.0572025 231.7001417 424.6456284 633.1885208 993.6684879 511.2734607 595.9979234 613.3561026 383.1575499 1.395942482 1.226798748 0.604712453 1.108279423 1.652553945 2.593367893 1.334368749 1.555490486 1.600793467 1 8.581793923 -5.681808368 4.854926743 1.14128669 1.827247491 0.389609371 0.387798081 0.15417865 6.529171639 0.054400875 0.110088984 2.08E-06 5.681808368 0.685960801 NLYIISVK ddPTM_HeLa_Curcumin_4h_R1 2 NLYIISVK 8 0 C9JD32;B9ZVP7;J3KT29;P62829 C9JD32 RPL23 60S ribosomal protein L23 0 0 ; ; 156.75 7.15E-06 13730400 9287.3 6355.1 7705.9 7657.5 7611.2 12773.4 9645.9 8346.3 8569.8 6952.9 FALSE FALSE TRUE 8552.200405 6904.406526 7991.487433 7625.815294 7520.441411 10124.05285 9916.537993 10891.04845 7629.714381 7194.512757 1.188711549 0.959676737 1.110775351 1.059948818 1.045302394 1.407190896 1.378347406 1.51379931 1.060490771 1 12.81268127 -5.243675757 8.0457119 1.077926608 1.428538658 0.864469026 0.067326717 0.069503578 25.41502497 0.011684538 0.029054158 5.71E-06 5.243675757 0.35061205 NLYIISVK(ac)GIK ddPTM_HeLa_Curcumin_4h_R1 1 NLYIISVKGIK 11 1 C9JD32;B9ZVP7;J3KT29;P62829 C9JD32 RPL23 60S ribosomal protein L23 0 1 NLYIISVK(1)GIK 124.42 1.37E-07 0 294.02 165.16 223.93 287.88 244.27 415.07 410.26 348.4 181.57 151 FALSE TRUE FALSE 270.7480068 179.4356945 232.2290428 286.6888288 241.3572398 328.9798032 421.7707914 454.6255562 161.6522253 156.2472388 1.732817865 1.148408739 1.48629214 1.83484093 1.544713633 2.105507949 2.699380769 2.909654979 1.034592525 1 7.287686884 -1 0.30273715 1.232598915 17.16747125 0.868117491 0.227600971 15.16610782 0.194006714 0.103236561 133.116398 0.1 1 15.93487233 NLYPSS(ph)SPYTR ddPTM_HeLa_Curcumin_4h_R1 1 NLYPSSSPYTR 11 0 Q9Y2Z0-2;Q9Y2Z0 Q9Y2Z0-2 SUGT1 Suppressor of G2 allele of SKP1 homolog 1 0 NLYPS(0.117)S(0.441)S(0.441)PYTR 112.84 0.0056649 75408000 5544.4 4733.1 5321.6 6016.5 5446.4 9765.3 8699.5 4951.1 5981.5 4256.9 TRUE FALSE FALSE 5105.55489 5142.208074 5518.823177 5991.605317 5381.455237 7739.866702 8943.584556 6460.667598 5325.344415 4404.826958 1.15908183 1.16740297 1.252903515 1.360236253 1.22171774 1.757132976 2.030405426 1.466724495 1.208979255 1 12.10486963 -5.590602968 0.762926032 1.075767292 1.836403857 0.652229878 0.174834777 0.314056437 0.309393985 0.030242786 0.139804235 2.57E-06 5.590602968 0.760636565 NLYPSSS(ph)PYTR ddPTM_HeLa_Curcumin_4h_R1 3 NLYPSSSPYTR 11 0 Q9Y2Z0-2;Q9Y2Z0 Q9Y2Z0-2 SUGT1 Suppressor of G2 allele of SKP1 homolog 1 0 NLYPS(0.031)S(0.103)S(0.865)PYT(0.001)R;NLYPS(0.023)S(0.077)S(0.9)PYTR;NLYPS(0.11)S(0.042)S(0.848)PYTR ;; 141.34 0.0012813 63698700 7590.6 6202.3 6808.5 7465.1 7054.8 12393.6 10622.8 5475.9 7990 5279.8 TRUE FALSE FALSE 6989.796 6738.399175 7060.828999 7434.211394 6970.676118 9823.027655 10920.84718 7145.476702 7113.51699 5463.272657 1.279415552 1.233399758 1.292417465 1.360761555 1.275915839 1.798011608 1.998957011 1.307911421 1.3020615 1 12.41554971 -5.631284313 0.268874237 1.00624202 1.961900467 0.389358052 0.215958835 2.419734587 0.258547942 0.155581747 0.7548102 2.34E-06 5.631284313 0.955658446 NLYSDDIPHALR ddPTM_HeLa_Curcumin_4h_R1 2 NLYSDDIPHALR 12 0 E5RIT4;P60228;H0YBR5 E5RIT4;P60228 EIF3E Eukaryotic translation initiation factor 3 subunit E 0 0 ; ; 104.94 0.0056556 16596200 11259.4 9536.8 10483.6 9536 11341.8 14970.6 10502.9 9497.7 11593.1 11286.5 FALSE FALSE TRUE 10368.20661 10361.1185 10872.13144 9496.542559 11206.55644 11865.52881 10797.58311 12393.50501 10321.36593 11678.70503 0.887787351 0.887180425 0.930936384 0.813150305 0.959571837 1.01599696 0.924553114 1.061205414 0.883776575 1 13.51159269 -1.00000949 0.989044715 0.933488155 112.8159153 0.322215359 0.057869756 1853.719993 2.532652223 0.009690428 469952.6678 0.099997815 1.00000949 111.8824271 T(ph)QTPPVS(ph)PAPQPTEER ddPTM_HeLa_Curcumin_4h_R1 2 TQTPPVSPAPQPTEER 16 0 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 2 0 T(0.523)QT(0.477)PPVS(1)PAPQPTEER;T(0.892)QT(0.12)PPVS(0.982)PAPQPT(0.005)EER ; 132.9 0.0020089 29695000 3944.6 3493.1 3651.5 3575.7 3724 4278.2 4350.7 5778.2 3900 3003.1 TRUE FALSE FALSE 3632.380748 3795.027999 3786.827802 3560.904701 3679.593732 3390.853095 4472.768933 7539.94658 3472.179757 3107.457501 1.168923709 1.22126465 1.218625774 1.145922253 1.184117154 1.091198542 1.439366083 2.426403765 1.11736999 1 11.60151895 -4.248530463 2.194314849 1.113261344 2.801333683 0.968448823 0.069304244 0.102779314 0.540079628 0.013201894 0.34134039 5.64E-05 4.248530463 1.688072339 up NMAPSQQS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 4 NMAPSQQSPVR 11 0 H7C3Q7;H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9 H7C3Q7 ABI2 Abl interactor 2 1 0 NMAPSQQS(1)PVR;NMAPSQQS(1)PVR;NMAPSQQS(1)PVR;NMAPSQQS(1)PVR ;;; 198.48 8.95E-06 390972000 19997.2 13613.6 15427.5 16353.9 17365.3 20458.3 14899.6 5832.17 18582.2 14437.3 TRUE FALSE FALSE 18414.40052 14790.29892 15999.25672 16286.2319 17158.23014 16215.01797 15317.64268 7610.371785 16543.77915 14938.9951 1.232639839 0.99004644 1.070972754 1.090182558 1.148553167 1.085415576 1.025346255 0.509429967 1.10742249 1 13.86679549 -4.244450412 3.01499924 1.100371842 0.400191512 0.873409011 0.065878519 0.136342003 1.749055193 0.012553794 0.232686064 5.70E-05 4.244450412 -0.700180331 NMDDDRLSR ddPTM_HeLa_Curcumin_4h_R1 1 NMDDDRLSR 9 1 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 76.221 0.008027 0 2266.9 1737.2 1642.2 1768.5 1715.7 2327 1536.9 1383.8 2417.3 2351.2 FALSE FALSE TRUE 2087.472473 1887.355827 1703.061377 1761.182416 1695.241398 1844.353969 1580.021278 1805.71425 2152.128238 2432.904025 0.858016778 0.775762549 0.700011739 0.723901312 0.696797482 0.758087434 0.649438392 0.742205295 0.884592329 1 11.24846369 -7.704923523 0.589290354 0.986755746 0.69756103 0.797395402 0.045203499 0.129502123 0.10438682 0.013428211 0.011188182 1.97E-08 7.704923523 -0.289194717 NMFHPMDFEDDPLVLNEIR ddPTM_HeLa_Curcumin_4h_R1 1 NMFHPMDFEDDPLVLNEIR 19 0 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 0 0 57.989 0.0065768 0 892.19 563.09 598.27 549.6 773.01 905.84 677.22 587.68 786.79 720.84 FALSE FALSE TRUE 821.5722201 611.7609905 620.4424125 547.3259008 763.7923606 717.9585731 696.2209706 766.8609267 700.4811055 745.8891363 1.101466934 0.820176834 0.831815859 0.733789881 1.024002527 0.962554002 0.933410793 1.028116498 0.939122279 1 9.542817404 -7.268668372 24.97495048 1.047914941 0.903352778 0.187089602 0.096081983 484.5903191 1674175.268 0.016538866 0.019118865 5.39E-08 7.268668372 -0.144562163 NMGGPYGGGNYGPGGS(ph)GGSGGYGGR ddPTM_HeLa_Curcumin_4h_R1 4 NMGGPYGGGNYGPGGSGGSGGYGGR 25 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 0 NMGGPY(0.026)GGGNYGPGGS(0.973)GGSGGYGGR;NMGGPYGGGNYGPGGS(0.975)GGS(0.025)GGYGGR;NMGGPYGGGNYGPGGS(0.629)GGS(0.371)GGYGGR;NMGGPYGGGNY(0.001)GPGGS(0.742)GGS(0.257)GGYGGR ;;; 232.87 1.63E-35 152515000 24174.87 20973.92 21941.96 24453.84 23577.99 29378.75 23425.42 18529.61 27206.65 22196.23 TRUE FALSE FALSE 22261.40353 22786.81219 22755.14834 24352.65649 23296.83787 23285.26608 24082.67424 24179.20279 24222.14856 22967.54734 0.969254714 0.992130847 0.990752212 1.06030723 1.014337209 1.013833377 1.048552285 1.052755108 1.054624954 1 14.48730918 -6.359976544 6.661997823 0.985889231 1.035801371 0.228346827 0.026914913 0.11748304 6.814173823 0.002789054 0.004271867 4.37E-07 6.359976544 0.04991214 NMGGPYGGGNYGPGGSGGS(ph)GGYGGR ddPTM_HeLa_Curcumin_4h_R1 1 NMGGPYGGGNYGPGGSGGSGGYGGR 25 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 0 NMGGPYGGGNYGPGGS(0.008)GGS(0.992)GGYGGR 195.31 1.68E-17 31181000 625.33 846.96 965.14 968.02 1089.5 1332.3 1163.9 751.24 1140.5 1031.4 TRUE FALSE FALSE 575.8344707 920.1674484 1000.908937 964.0145897 1076.508424 1055.965962 1196.555902 980.2896177 1015.390003 1067.241073 0.539554263 0.862192687 0.937847092 0.903277258 1.008683465 0.989435272 1.121167402 0.918526884 0.951415785 1 10.05967038 -6.732235814 2.572861925 0.780352091 0.991874996 0.194992651 0.129746876 0.315863221 4.292438158 0.029457107 0.041946806 1.85E-07 6.732235814 0.211522906 NMGGPYGGGNYGPGGSGGSGGYGGR ddPTM_HeLa_Curcumin_4h_R1 3 NMGGPYGGGNYGPGGSGGSGGYGGR 25 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 ;; ;; 281.65 1.27E-100 13817100 1679.1 1927.16 1667.82 1577.22 1863.38 2392.16 1657.7 1793.01 1802.72 1916.63 FALSE FALSE TRUE 1546.197463 2093.735123 1729.630876 1570.693882 1841.160411 1895.999051 1704.210601 2339.690495 1604.966126 1983.23275 0.779634898 1.055718308 0.872127024 0.79198666 0.928363255 0.956014392 0.859309428 1.179735709 0.80926766 1 10.95363829 -4.256166679 24.454958 0.900469916 1.17973587 0.492422664 0.086635218 311.4814725 1444597.617 0.013311308 0.150260394 5.54E-05 4.256166679 0.279265954 NMPGLSAATLASLGGTS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 NMPGLSAATLASLGGTSSR 19 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 0 NMPGLSAATLASLGGT(0.026)S(0.655)S(0.319)R 172.55 3.47E-06 47608000 1768.8 1308.4 1280.2 1761.9 1620.6 1889.7 1589.7 1436.6 1305.2 1383 TRUE FALSE FALSE 1628.797614 1421.492266 1327.645338 1754.609725 1601.275403 1497.754919 1634.302704 1874.612727 1162.022825 1431.059147 1.138176306 0.993314825 0.927736174 1.226091688 1.11894425 1.046605881 1.14202317 1.309947762 0.812001955 1 10.48286759 -1.000000356 0.798478654 1.06132259 62.16737131 0.349599298 0.111829305 355.2539623 1.174120369 0.013799878 39287.98235 0.099999918 1.000000356 61.10604872 NMPGLSAATLASLGGTSS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 NMPGLSAATLASLGGTSSR 19 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 0 NMPGLSAATLASLGGT(0.018)S(0.193)S(0.788)R 211.43 3.63E-14 53002000 1349 1279.7 1274.4 1710.2 1277.4 1733.6 1818.5 1666.8 1198.9 1361.8 TRUE FALSE FALSE 1242.225227 1390.311566 1321.630385 1703.123646 1262.167839 1374.031818 1869.522216 2174.999647 1067.383669 1409.122449 0.881559461 0.98665064 0.937910248 1.208641341 0.895711966 0.975097529 1.326728005 1.543513588 0.757481133 1 10.46058127 -4.614356485 2.673256564 0.961197351 1.529275877 0.7671796 0.108722812 0.085820572 1.136787 0.012949876 0.076145004 2.43E-05 4.614356485 0.568078526 NMQNAEIIRK ddPTM_HeLa_Curcumin_4h_R1 1 NMQNAEIIRK 10 1 C9JJQ0;Q8WVM7-2;Q8WVM7 C9JJQ0 STAG1 Cohesin subunit SA-1 0 0 91.853 0.019279 4833100 1003.1 899.96 951.28 1045.3 1048.7 1114.8 882.53 1027.2 1096.2 852.15 FALSE FALSE TRUE 923.7035765 977.7485323 986.5352736 1040.974826 1036.194937 883.5779136 907.2914166 1340.388551 975.9496026 881.7621491 1.047565466 1.108857455 1.118822434 1.180561931 1.175141095 1.002059245 1.028952555 1.520124846 1.106817302 1 9.784245738 -4.259495907 24.79687339 1.054746741 1.520125024 0.776332783 0.068234423 55.88633747 712995.0964 0.010793589 0.093614835 5.50E-05 4.259495907 0.465378283 NMSVIAHVDHGK ddPTM_HeLa_Curcumin_4h_R1 3 NMSVIAHVDHGK 12 0 P13639 P13639 EEF2 Elongation factor 2 0 0 ;; ;; 87.216 0.0051354 22100100 9456.5 9458.7 7871.4 7398.9 11416.7 14517.6 9015.3 8525.1 11809.8 8953.4 FALSE FALSE TRUE 8708.008047 10276.26788 8163.121008 7368.285312 11280.56331 11506.48611 9268.245055 11124.36375 10514.29449 9264.529984 0.939929825 1.109205529 0.881115504 0.795322086 1.217607729 1.24199351 1.000400999 1.200747773 1.134897777 1 13.17750207 -5.739287127 24.9984085 0.96387471 1.158903218 0.402640397 0.111683324 156.9545479 177119.341 0.01399577 0.027973652 1.82E-06 5.739287127 0.195028508 NMTVEQLLT(ph)GS(ph)PTSPTVEPEKPTR ddPTM_HeLa_Curcumin_4h_R1 1 NMTVEQLLTGSPTSPTVEPEKPTR 24 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 2 0 NMT(0.004)VEQLLT(0.49)GS(0.49)PT(0.49)S(0.49)PT(0.036)VEPEKPTR 56.461 0.010575 23955000 2314.2 1681.3 1758.1 2191.9 2049.3 2447.3 1538.7 1969.1 2189.8 1795.2 TRUE FALSE FALSE 2131.028628 1826.62408 1823.256733 2182.830499 2024.863436 1939.702393 1581.871781 2569.469525 1949.584419 1857.583066 1.147205025 0.983333727 0.98152097 1.17509173 1.090052699 1.04420762 0.851575259 1.383232638 1.04952745 1 10.85921101 -6.27172447 24.77479777 1.057445193 1.089906416 0.052496296 0.132235934 3149.753378 7587136.185 0.019944101 0.030655678 5.35E-07 6.27172447 0.032461223 NMTVEQLLTGS(ph)PTS(ph)PTVEPEKPTR ddPTM_HeLa_Curcumin_4h_R1 1 NMTVEQLLTGSPTSPTVEPEKPTR 24 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 2 0 NMT(0.003)VEQLLT(0.079)GS(0.815)PT(0.48)S(0.622)PT(0.001)VEPEKPTR 79.935 0.00045768 20107000 1821.3 1499.3 1543.2 1960.4 1421.6 2077.2 1611.5 1144.9 1788.1 1455.7 TRUE FALSE FALSE 1677.142183 1628.892811 1600.39235 1952.288384 1404.648348 1646.365305 1656.714353 1493.97474 1591.949904 1506.285467 1.113429174 1.08139715 1.062476128 1.29609455 0.932524664 1.092996873 1.099867448 0.991827096 1.056871316 1 10.5567795 -2.568006023 14.36523589 1.066854684 0.642899847 0 0.092177503 0 0 0.011813566 0 0.002703921 2.568006023 -0.423954837 HAQDSDPRS(ph)PTLGIAR ddPTM_HeLa_Curcumin_4h_R1 2 HAQDSDPRSPTLGIAR 16 1 Q99618;F5GX58;F8WDL1;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 0 HAQDSDPRS(0.776)PT(0.224)LGIAR;HAQDS(0.003)DPRS(0.684)PT(0.313)LGIAR ; 64.249 0.014786 44906000 5910.8 4447 5012.5 5402.9 5467 7031.9 4407.2 1918.46 6448.3 5158.5 TRUE FALSE FALSE 5442.953943 4831.378865 5198.267659 5380.544231 5401.809596 5573.404674 4530.854171 2503.389622 5740.937623 5337.757491 1.019707986 0.905132703 0.973867334 1.008015864 1.011999815 1.044147225 0.848831027 0.468996508 1.075533617 1 12.38201805 -4.309233225 2.498516016 1.001348011 0.382752499 0.931992921 0.043738826 0.068852494 0.573875198 0.005337559 0.085964785 4.91E-05 4.309233225 -0.618595512 down TVTDVSTIDGNAAELVSGRPVSDTTEPS(ph)SPEGK ddPTM_HeLa_Curcumin_4h_R1 1 TVTDVSTIDGNAAELVSGRPVSDTTEPSSPEGK 33 1 C9JA33;B1ALY0;Q8IXS6;Q8IXS6-2 C9JA33 PALM2 Paralemmin-2 1 0 TVTDVSTIDGNAAELVS(0.001)GRPVS(0.006)DT(0.072)T(0.072)EPS(0.8)S(0.048)PEGK 124.22 3.41E-18 12776000 6759.4 5084.2 6252.9 5776.7 6766.4 7003.1 6340.1 9692.9 5881 4386.9 TRUE FALSE FALSE 6224.386358 5523.655593 6484.637975 5752.797546 6685.715099 5550.578119 6517.986142 12648.22059 5235.869014 4539.344448 1.371208206 1.216839933 1.428540629 1.267319017 1.472837141 1.222770861 1.435887101 2.786354006 1.153441664 1 12.14826825 -4.248491583 3.053733663 1.230860128 3.059527693 0.919378729 0.133811754 0.096884782 1.303253449 0.024488508 0.4335017 5.64E-05 4.248491583 1.828667565 up SPSVPKS(ph)PTPK ddPTM_HeLa_Curcumin_4h_R1 1 SPSVPKSPTPK 11 1 Q9NVD7-2;Q9NVD7 Q9NVD7-2 PARVA Alpha-parvin 1 0 SPS(0.001)VPKS(0.918)PT(0.08)PK 86.498 0.0092397 619900000 9666.9 8268 8528.2 8760 10219 10981 9970.3 13624 8750.4 8323.7 TRUE FALSE FALSE 8901.754665 8982.649079 8844.262594 8723.753441 10097.1451 8703.416819 10250.03978 17777.89488 7790.503012 8612.947955 1.033531691 1.042923878 1.026856616 1.01286499 1.17232162 1.010503821 1.190073345 2.064089435 0.904510634 1 13.0722914 -4.248278397 2.847979618 1.029784327 2.268471944 0.961624478 0.061907984 0.045160304 0.492925268 0.006795374 0.130864415 5.65E-05 4.248278397 1.238687617 up NMVVDDDS(ph)PEMYK ddPTM_HeLa_Curcumin_4h_R1 1 NMVVDDDSPEMYK 13 0 E7ETM8;Q0ZGT2-4;E7EUA0;Q0ZGT2-2;Q0ZGT2;Q0ZGT2-3;H7BXY5 E7ETM8 NEXN Nexilin 1 0 NMVVDDDS(1)PEMYK 125.61 0.0019897 5561500 2819.1 2110.6 2772.9 3199.1 2407.3 3508.2 2823.4 2549.5 2863.8 2902.1 TRUE FALSE FALSE 2595.96526 2293.030859 2875.666113 3185.862972 2378.59452 2780.559774 2902.617005 3326.830814 2549.648305 3002.947759 0.864472335 0.763593323 0.957614432 1.060911886 0.792086547 0.925943439 0.966589244 1.107855041 0.849048505 1 11.55216366 -4.283749821 2.539370497 0.922284896 1.142230048 0.317183255 0.087968861 0.500847078 4.197849437 0.012871243 0.230595201 5.20E-05 4.283749821 0.219945152 NNALS(ph)YYKSEDET(ph)EYGCRGS(ph)ICLSK ddPTM_HeLa_Curcumin_4h_R1 1 NNALSYYKSEDETEYGCRGSICLSK 25 2 Q9Y5P4;Q9Y5P4-3;A0A2R8YCI0;A0A2R8YFI2;A0A2R8YEA4;A0A2R8Y5H3;A0A2R8Y7Q9;A0A2R8YEK8;A0A2R8YE18;A0A2R8Y5S9;A0A2R8Y7C5;Q9Y5P4-2 Q9Y5P4 COL4A3BP Collagen type IV alpha-3-binding protein 3 0 NNALS(0.308)Y(0.223)Y(0.223)KS(0.249)EDET(0.976)EY(0.049)GCRGS(0.824)ICLS(0.149)K 62.19 0.0074075 0 3518.2 3263.1 3898.6 3140.6 3485.9 4677.2 2148.7 2403.6 3584.4 3343.9 TRUE FALSE FALSE 3239.730758 3545.147824 4043.085546 3127.605029 3444.332919 3707.095997 2208.986739 3136.446575 3191.200288 3460.100276 0.936311234 1.024579504 1.168487969 0.903905893 0.995443093 1.071383978 0.638416971 0.906461179 0.922285493 1 11.75659813 -4.770009812 24.99905011 0.98995393 0.772439056 0.479809393 0.095194544 100.2524197 292429.3043 0.012303789 0.037770976 1.70E-05 4.770009812 -0.217514874 NNASTDYDLSDK ddPTM_HeLa_Curcumin_4h_R1 3 NNASTDYDLSDK 12 0 G5E9G0;P39023;B5MCW2 G5E9G0 RPL3 60S ribosomal protein L3 0 0 ;; ;; 222.2 7.44E-29 27298400 11219.1 9899.1 11228.6 10161.5 9948.2 14200 10596.2 9375.4 11387.9 10205 FALSE FALSE TRUE 10331.0964 10754.73409 11644.74179 10119.45441 9829.574212 11254.75993 10893.50085 12233.9163 10138.67586 10559.62299 0.978358451 1.01847709 1.102761131 0.958315881 0.930864125 1.065829712 1.031618351 1.158556164 0.960136159 1 13.36627071 -3.772084731 1.110210329 0.995865206 1.445255844 0.497482892 0.047948209 2.619432403 1.229497074 0.006933968 1.791322686 0.000169011 3.772084731 0.449390638 NNDQPQSANANEPQDS(ph)TVNLQSPLK ddPTM_HeLa_Curcumin_4h_R1 1 NNDQPQSANANEPQDSTVNLQSPLK 25 0 P37275-3;P37275-4;P37275-5;P37275;P37275-2 P37275-3 ZEB1 Zinc finger E-box-binding homeobox 1 1 0 NNDQPQSANANEPQDS(0.645)T(0.124)VNLQS(0.23)PLK 88.627 2.15E-05 10925000 4983.2 3711.6 4512 4450.2 4773.5 5837.6 4696.4 2619.9 4410.9 3445.9 TRUE FALSE FALSE 4588.774462 4032.414165 4679.218689 4431.786252 4716.57913 4626.815957 4828.168344 3418.695449 3927.035306 3565.644769 1.286941005 1.130907431 1.312306467 1.242913004 1.322784359 1.297609901 1.354080021 0.958787448 1.101353489 1 11.79994726 -9.350346931 0.762534507 0.97570827 1.25058909 0.279230967 0.114860552 0.624363801 0.555516728 0.110658461 0.020639467 4.46E-10 9.350346931 0.27488082 SLGK(ac)APASLPTEEK ddPTM_HeLa_Curcumin_4h_R1 1 SLGKAPASLPTEEK 14 1 Q96L73-2;Q96L73-3;Q96L73 Q96L73-2 NSD1 "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific" 0 1 SLGK(1)APASLPTEEK 166.6 6.30E-05 1413200 1054.7 891.31 836.97 772.41 675.77 1051.7 534.06 265.82 1197.8 943.32 FALSE TRUE FALSE 971.2193821 968.3508648 867.9888445 769.2139721 667.7118841 833.5655649 549.0442863 346.8672943 1066.404337 976.1002998 0.994999574 0.992060821 0.889241449 0.788048085 0.68406073 0.853975319 0.562487571 0.355360299 1.092515121 1 9.93088559 -4.290958265 0.441064147 1.00697351 3.72E-16 0.869377451 0.078730106 1.133344303 0.150524266 0.017963323 0.593163945 5.12E-05 4.290958265 -1.00697351 down NNK(ac)K(ac)TSK(ac)NK ddPTM_HeLa_Curcumin_4h_R1 2 NNKKTSKNK 9 3 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 0 3 ; NNK(1)K(1)TSK(1)NK;NNK(1)K(1)TSK(1)NK 169.93 1.32E-15 84457000 6659.4 5396.9 5753.6 4716 5618.1 6682.2 4049.9 2241.6 6154.8 4789.7 FALSE TRUE FALSE 6132.301463 5863.383988 5966.833477 4696.486442 5551.107827 5296.236396 4163.529294 2925.053521 5479.633839 4956.141718 1.237313582 1.183054142 1.20392713 0.947609392 1.120046226 1.068620854 0.840074705 0.590187627 1.10562493 1 12.27500173 -4.371437533 1.371578295 1.117459408 0.425681844 0.800876717 0.083383098 0.424644542 0.808397742 0.0156804 0.381799077 4.25E-05 4.371437533 -0.691777564 NNLAGAEELFAR ddPTM_HeLa_Curcumin_4h_R1 2 NNLAGAEELFAR 12 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 ; ; 163.9 4.32E-06 7100600 2400.1 2421.6 2635.45 2841.43 2296.93 2757.26 2115.74 1796.91 2811.02 2189.27 FALSE FALSE TRUE 2210.129552 2630.912314 2733.122095 2829.672916 2269.54061 2185.373195 2175.10197 2344.779587 2502.658139 2265.34697 0.975625183 1.161372783 1.206491602 1.249112367 1.001851213 0.964696898 0.960162836 1.035064217 1.104757096 1 11.14551632 -3.856429933 18.24721195 1.028565638 3.754709123 0 0.108088803 10249.62493 1325078.439 0.016169097 20126.72917 0.000139178 3.856429933 2.726143485 NNPS(ph)PPPDSDLER ddPTM_HeLa_Curcumin_4h_R1 2 NNPSPPPDSDLER 13 0 E9PLN6;F2Z2Y1;O95677-3;O95677-2;O95677-4;O95677;E7ESD5;O95677-5 E9PLN6 EYA4 Eyes absent homolog;Eyes absent homolog 4 1 0 NNPS(1)PPPDSDLER;NNPS(0.998)PPPDS(0.002)DLER ; 169.98 0.00018005 168027000 4289.1 3991 3733 3972.7 3405.7 4041.7 3140 2630 4059.5 3470.7 TRUE FALSE FALSE 3949.613209 4335.964256 3871.348264 3956.26202 3365.089252 3203.405861 3228.099949 3431.874893 3614.183006 3591.306567 1.099770553 1.207350076 1.077977664 1.101621916 0.937009745 0.891988974 0.898865048 0.95560622 1.006369949 1 11.8102931 -5.688129256 5.723854284 1.067469929 0.914681593 0.651126688 0.057300297 0.12173959 6.986291651 0.009762505 0.019632445 2.05E-06 5.688129256 -0.152788336 NNQESDCVSK(ac)KK ddPTM_HeLa_Curcumin_4h_R1 1 NNQESDCVSKKK 12 2 H3BV17;A6NDG6 H3BV17 PGP Phosphoglycolate phosphatase 0 1 NNQESDCVSK(0.95)K(0.05)K 84.734 0.0077163 2370700 1691.1 1122.2 1656.9 1515.6 1388.3 1671.7 1404.1 1396.3 1417.3 1091.1 FALSE TRUE FALSE 1557.247651 1219.197968 1718.306172 1509.328849 1371.745429 1324.970576 1443.495267 1822.025442 1261.825736 1129.015644 1.379296788 1.079876948 1.52195072 1.336853796 1.214992402 1.173562637 1.278543194 1.613817711 1.117633527 1 10.14084976 -9.407137092 0.77029093 0.964350287 1.320851573 0.314752842 0.153251727 0.70511251 0.622759892 0.165586767 0.02864993 3.92E-10 9.407137092 0.356501285 NNQITNNQR ddPTM_HeLa_Curcumin_4h_R1 2 NNQITNNQR 9 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 0 ; ; 211.48 1.03E-27 7214700 2825.2 3523.5 2040.81 1752.29 1720.57 2616.04 1620.33 2105.97 1953.17 2699.2 FALSE FALSE TRUE 2601.582439 3828.05564 2116.444214 1745.039488 1700.053326 2073.443815 1665.792099 2748.070558 1738.912138 2792.996999 0.931466249 1.370590674 0.757768166 0.624791036 0.608684265 0.742372375 0.596417432 0.983914612 0.622597209 1 11.44759831 -6.547769487 24.99991359 1.000155352 0.699928498 0.296029934 0.197895422 144.1347715 144766.3768 0.02373629 0.033568884 2.83E-07 6.547769487 -0.300226854 NNRPSEGPLQTR ddPTM_HeLa_Curcumin_4h_R1 2 NNRPSEGPLQTR 12 1 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 ; ; 108.72 0.0018298 3551500 1763 1311.09 1407.61 1293.5 1321.85 2013.93 1390.57 1188.03 1362.78 1249.89 FALSE FALSE TRUE 1623.45669 1424.414777 1459.777265 1288.14784 1306.087802 1596.218216 1429.585652 1550.254878 1213.286444 1293.323584 1.25525948 1.101359934 1.128702269 0.995998105 1.009869315 1.234198646 1.105358063 1.198659714 0.938115146 1 10.33686756 -9.68687351 1.571450321 1.000277353 1.143811544 0.334610743 0.084670971 0.445420414 1.988143039 0.065363105 0.014640998 2.06E-10 9.68687351 0.143534192 NNS(ph)GEEFDCAFR ddPTM_HeLa_Curcumin_4h_R1 2 NNSGEEFDCAFR 12 0 Q08J23-2;Q08J23;Q08J23-3 Q08J23-2 NSUN2 tRNA (cytosine(34)-C(5))-methyltransferase 1 0 NNS(1)GEEFDCAFR;NNS(1)GEEFDCAFR ; 207.4 3.96E-09 52646000 3026.62 2523.15 2761.7 2877.66 3116.8 3700.4 2180.62 2392.44 3115.6 2515.04 TRUE FALSE FALSE 2787.059833 2741.239843 2864.051031 2865.753005 3079.634196 2932.895328 2241.802328 3121.883943 2773.826475 2602.437453 1.070942101 1.053335534 1.100526366 1.101180358 1.183365307 1.126980141 0.861424095 1.19959999 1.065857115 1 11.34564777 -8.717067085 0.593102578 0.997389115 1.087313761 0.041650125 0.08923995 1.459133998 0.972863121 0.065159147 0.021333356 1.92E-09 8.717067085 0.089924647 HAS(ph)APSHVQPSDSEK ddPTM_HeLa_Curcumin_4h_R1 2 HASAPSHVQPSDSEK 15 0 A0A3B3IRT3;O60343-2;O60343-3;O60343 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 1 0 HAS(0.949)APS(0.051)HVQPSDSEK;HAS(0.993)APS(0.007)HVQPSDSEK ; 113.28 0.00067703 57799000 10174.9 8735 9486.8 8195.6 12597.6 14341.3 8064.8 2908.9 11309.5 9024.1 TRUE FALSE FALSE 9369.545928 9490.014478 9838.389153 8161.688779 12447.38185 11366.75272 8291.076583 3795.810219 10068.87614 9337.686803 1.003411886 1.016313213 1.053621669 0.874058956 1.333026274 1.217298562 0.887915472 0.406504341 1.07830519 1 13.18884948 -4.309214256 3.426005118 1.032951054 0.35741765 0.713253017 0.125170493 0.11208437 2.213420888 0.017494855 0.181585786 4.91E-05 4.309214256 -0.675533403 down NNS(ph)PPTVGAFGHTR ddPTM_HeLa_Curcumin_4h_R1 2 NNSPPTVGAFGHTR 14 0 Q86XL3;Q86XL3-3;F5H1D4 Q86XL3 ANKLE2 Ankyrin repeat and LEM domain-containing protein 2 1 0 NNS(1)PPTVGAFGHTR;NNS(0.998)PPT(0.002)VGAFGHTR ; 122.97 0.00072856 48651000 5685.1 4748.6 5168.4 5531.6 5049.4 6214.7 4302.9 2413.3 5985.2 5320.9 TRUE FALSE FALSE 5235.118336 5159.047825 5359.945451 5508.711705 4989.189203 4925.701166 4423.627793 3149.104061 5328.638534 5505.800879 0.950836845 0.937020415 0.973508772 1.000528683 0.906169568 0.89463845 0.803448561 0.571961124 0.967822602 1 12.42673672 -3.807232832 0.856580426 0.973936301 8.88E-17 0.961690176 0.024056301 0.629918368 0.199991987 0.004349052 0.694231201 0.000155872 3.807232832 -0.973936301 SLPTPAVLLSPT(ph)KEPPPLLAKPK ddPTM_HeLa_Curcumin_4h_R1 1 SLPTPAVLLSPTKEPPPLLAKPK 23 2 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 0 SLPT(0.005)PAVLLS(0.41)PT(0.585)KEPPPLLAKPK 70.987 0.00069123 915570000 3333.5 3019.8 3721.2 3439.2 3186.2 4213.7 3721.8 5539.9 3760.4 3303.9 TRUE FALSE FALSE 3069.649958 3280.818056 3859.110946 3424.969502 3148.206646 3339.731122 3826.223691 7228.990007 3347.893528 3418.710279 0.897897074 0.959665426 1.128820704 1.001830872 0.920875532 0.976897967 1.119200921 2.114537184 0.979285536 1 11.73923645 -4.248156433 3.036655539 0.967428998 2.318329922 0.96931094 0.05996 0.052315373 0.691367364 0.009647774 0.172360702 5.65E-05 4.248156433 1.350900924 up NNSFTAPSTVGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 NNSFTAPSTVGKR 13 1 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 0 1 ; NNSFTAPSTVGK(1)R;NNSFTAPSTVGK(1)R 223.22 1.01E-28 8431700 3115.4 2694.47 2266.69 2441.74 2441.3 3625 2758.78 3434.7 3326.8 2436.02 FALSE TRUE FALSE 2868.812803 2927.36798 2350.695525 2431.636727 2412.189092 2873.134138 2836.183942 4481.924219 2961.858363 2520.671514 1.138114501 1.161344493 0.93256718 0.964678148 0.956962888 1.13982886 1.12516999 1.778067548 1.175027506 1 11.29959241 -4.198724618 2.622760022 1.053176562 1.999940064 0.857021199 0.087528077 0.172407878 1.309480647 0.012500818 0.380707003 6.33E-05 4.198724618 0.946763502 NNTAAET(ph)EDDESDGEDRGGGT(ph)SGVR ddPTM_HeLa_Curcumin_4h_R1 1 NNTAAETEDDESDGEDRGGGTSGVR 25 1 A0A590UJS4;Q6KC79-2 A0A590UJS4 NIPBL Nipped-B-like protein 2 0 NNT(0.009)AAET(0.959)EDDES(0.395)DGEDRGGGT(0.496)S(0.141)GVR 86.628 4.41E-05 23949000 2146.9 1969.1 2045.2 1991.7 2243.9 2509.2 2312.7 1663.9 2176.9 2297.9 TRUE FALSE FALSE 1976.9706 2139.30023 2120.996911 1983.458873 2217.142958 1988.763635 2377.588138 2171.21545 1938.099516 2377.751854 0.831445298 0.899715513 0.892017772 0.834174041 0.932453466 0.83640504 0.999931147 0.913137949 0.815097468 1 11.21538245 -9.524112428 1.284734706 0.999905832 0.886414627 0 0.075068377 0.355710068 1.05258283 0.035069646 0.008436935 2.99E-10 9.524112428 -0.113491205 NNTAAETEDDES(ph)DGEDRGGGTSGSLR ddPTM_HeLa_Curcumin_4h_R1 2 NNTAAETEDDESDGEDRGGGTSGSLR 26 1 Q6KC79 Q6KC79 NIPBL Nipped-B-like protein 1 0 NNTAAETEDDES(1)DGEDRGGGTSGSLR;NNTAAET(0.001)EDDES(0.998)DGEDRGGGTSGSLR ; 86.793 2.06E-05 18990600 1281.48 904.36 1050.62 1215.85 920.25 1135.41 808.76 448.82 816.05 1007.56 TRUE FALSE FALSE 1180.049506 982.5288487 1089.556901 1210.819135 909.2766198 899.9131673 831.4516289 585.6631519 726.5313567 1042.572635 1.131863111 0.942408055 1.045065701 1.161376286 0.872147023 0.86316592 0.797499954 0.561748057 0.696864019 1 10.02593218 -4.258890407 0.712481152 1.059217442 0.273626306 0.423041854 0.136453118 0.923127168 0.324776209 0.013584167 0.582567021 5.51E-05 4.258890407 -0.785591135 NNTAAETEDDES(ph)DGEDRGGGTSGVR ddPTM_HeLa_Curcumin_4h_R1 1 NNTAAETEDDESDGEDRGGGTSGVR 25 1 A0A590UJS4;Q6KC79-2 A0A590UJS4 NIPBL Nipped-B-like protein 1 0 NNTAAETEDDES(1)DGEDRGGGTSGVR 152.64 3.75E-09 57873000 781.37 793.95 798.5 816.03 798.96 851.55 579.86 315.61 654.75 588.2 TRUE FALSE FALSE 719.52374 862.5755002 828.0931124 812.6534841 789.4329238 674.9289311 596.129311 411.8380361 582.9255631 608.6399062 1.182182983 1.417218114 1.360563289 1.335195862 1.297044304 1.108913373 0.979444997 0.676653029 0.957751138 1 9.249445119 -4.365707379 1.923814384 1.165995106 0.589500925 0.545665133 0.148223426 0.462988751 2.100268026 0.02485673 0.437612274 4.31E-05 4.365707379 -0.576494181 NNTAAETEDDESDGEDRGGGT(ph)SGVR ddPTM_HeLa_Curcumin_4h_R1 1 NNTAAETEDDESDGEDRGGGTSGVR 25 1 A0A590UJS4;Q6KC79-2 A0A590UJS4 NIPBL Nipped-B-like protein 1 0 NNTAAETEDDES(0.202)DGEDRGGGT(0.592)S(0.206)GVR 108.99 1.86E-07 42119000 764.68 566.14 787.64 583.76 531.02 717.12 573.57 280.67 463.31 592.5 TRUE FALSE FALSE 704.1547711 615.0746189 816.8306313 581.3445558 524.6879333 568.3812284 589.6628305 366.244991 412.4860521 613.0893309 1.148535353 1.003238171 1.332319109 0.948221616 0.855809923 0.927077344 0.961789418 0.597376226 0.672799267 1 9.259953489 -6.008583925 21.17025218 1.086175815 0.857440735 0.170240258 0.182492312 39.6354986 97755.67713 0.018759682 0.03276191 9.80E-07 6.008583925 -0.22873508 NNTITTTS(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 NNTITTTSSK 10 0 H0YM23;O75179-6;O75179-7;O75179-2;O75179 H0YM23 ANKRD17 Ankyrin repeat domain-containing protein 17 1 0 NNTITTT(0.001)S(0.922)S(0.077)K 166.11 0.00055611 2802000 2278.8 2224.1 2243.8 2071 2502.2 3059.5 2755.2 1193.1 1970 2002.7 TRUE FALSE FALSE 2098.430575 2416.341294 2326.957202 2062.430751 2472.362899 2424.925212 2832.503497 1556.870698 1753.895929 2072.293676 1.012612546 1.166022616 1.122889689 0.995240576 1.193056239 1.170164847 1.366844637 0.751278989 0.846354911 1 11.01701275 -7.299149165 11.26751131 1.005933518 1.120941955 0.14475976 0.157519575 1.584324491 471.1497929 0.023253337 0.026612502 5.02E-08 7.299149165 0.115008437 NNTVTPGGKPNK ddPTM_HeLa_Curcumin_4h_R1 2 NNTVTPGGKPNK 12 1 C9K025;P18077 C9K025 RPL35A 60S ribosomal protein L35a 0 0 ; ; 124.38 0.00037403 11975500 7595.3 7485.7 6496.4 5807.3 6809.6 8804.3 7163.8 6280 7440.2 8045.8 FALSE FALSE TRUE 6994.12399 8132.730552 6737.162299 5783.270931 6728.399967 6978.188935 7364.796948 8194.74309 6624.028674 8325.390951 0.840095562 0.976858697 0.809230742 0.694654577 0.808178259 0.838181531 0.884618751 0.9843073 0.795641756 1 13.02330231 -9.30205541 0.597407127 1.024807012 0.845773301 0 0.101685085 1.184503846 0.596095836 0.117684957 0.019196029 4.99E-10 9.30205541 -0.179033711 NNVGERDDDVPADMVAEES(ph)GPGAQNSPYQLR ddPTM_HeLa_Curcumin_4h_R1 1 NNVGERDDDVPADMVAEESGPGAQNSPYQLR 31 1 Q86XK2-4;Q86XK2;Q86XK2-5 Q86XK2-4 FBXO11 F-box only protein 11 1 0 NNVGERDDDVPADMVAEES(0.63)GPGAQNS(0.364)PY(0.006)QLR 59.555 0.0034243 3559800 919.95 732.21 737.88 788.67 826.91 1028.6 768.33 935.59 885.36 750.64 TRUE FALSE FALSE 847.1349868 795.4989697 765.2264819 785.4066925 817.0496383 815.2567653 789.8872719 1220.847084 788.2382231 776.7246841 1.09065027 1.024171094 0.985196554 1.011177717 1.051916664 1.049608416 1.016946272 1.571788703 1.014823192 1 9.601259505 -4.260191152 24.99999907 1.03618042 1.571788876 0.96765512 0.02983074 16.62349068 332903.0089 0.005336307 0.044133677 5.49E-05 4.260191152 0.535608456 NNVGERDDDVPADMVAEESGPGAQNS(ph)PYQLR ddPTM_HeLa_Curcumin_4h_R1 1 NNVGERDDDVPADMVAEESGPGAQNSPYQLR 31 1 Q86XK2-4;Q86XK2;Q86XK2-5 Q86XK2-4 FBXO11 F-box only protein 11 1 0 NNVGERDDDVPADMVAEES(0.007)GPGAQNS(0.992)PY(0.001)QLR 107.6 4.94E-11 4882000 755.41 661.01 573.84 627.01 621.95 1049.1 883.34 312.79 931.07 874.44 TRUE FALSE FALSE 695.6185014 718.144759 595.1070152 624.4155988 614.5336525 831.5048342 908.124143 408.1582311 828.9339504 904.8267249 0.768786423 0.793682082 0.657702739 0.690094116 0.679172747 0.918965821 1.003644254 0.451089938 0.916124522 1 9.821497731 -8.99078563 0.675282308 1.011519594 0.751320839 0.252014573 0.144027482 0.799082731 0.633907778 0.115163053 0.030772917 1.02E-09 8.99078563 -0.260198755 NNWNDVDDFNWLAR ddPTM_HeLa_Curcumin_4h_R1 1 NNWNDVDDFNWLAR 14 0 Q15814 Q15814 TBCC Tubulin-specific chaperone C 0 0 185.57 1.21E-21 0 203.63 349.05 265.8 283.25 427.61 425.97 316.98 349.48 339.9 201.72 FALSE FALSE TRUE 187.5124706 379.2203267 275.6507818 282.0779866 422.51103 337.6190203 325.8736057 456.0348432 302.6138204 208.729755 0.898350456 1.816800516 1.320610863 1.351402854 2.024201246 1.617493492 1.561222576 2.184809939 1.449787647 1 7.705492465 -6.81710154 0.772948014 0.935496754 1.801228399 0.336915124 0.318034444 0.279911214 0.337686988 0.060817239 0.096582824 1.52E-07 6.81710154 0.865731645 NNYYSSRFS(ph)PDSQYIDNR ddPTM_HeLa_Curcumin_4h_R1 1 NNYYSSRFSPDSQYIDNR 18 1 F5GZI3;Q5VWV2;Q8TEW0-4;Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-3;Q8TEW0-7;Q8TEW0-6;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 F5GZI3;Q5VWV2 PARD3 Partitioning defective 3 homolog 1 0 NNYYS(0.051)S(0.158)RFS(0.781)PDS(0.009)QY(0.001)IDNR 119.51 0.0036094 10955000 294.9 225.81 371.83 445.92 395.75 660.69 477.43 117.39 643.65 351.82 TRUE FALSE FALSE 271.5583538 245.3280102 385.6103469 444.0749012 391.0309397 523.6554465 490.8254009 153.1816706 573.0432053 364.0457188 0.745945742 0.673893408 1.059236044 1.21983278 1.074125912 1.438433195 1.348252089 0.420775915 1.574096812 1 8.507975833 -6.566334004 9.989618879 0.861326424 1.132224067 0 0.351192534 0.525968441 117.1350434 0.04195672 0.059386982 2.71E-07 6.566334004 0.270897642 NPDDITNEEYGEFYK ddPTM_HeLa_Curcumin_4h_R1 4 NPDDITNEEYGEFYK 15 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 ;;; ;;; 244 3.23E-48 139046800 11310.86 9547.87 9556.06 10145.95 10329.9 11526.07 9318.26 9266.72 11235.29 9599.2 FALSE FALSE TRUE 10415.5935 10373.14534 9910.21599 10103.96875 10206.72269 9135.433156 9579.705297 12092.10027 10002.8068 9932.771485 1.048608992 1.044335446 0.997729184 1.017235599 1.02758054 0.9197265 0.964454413 1.217394389 1.007050933 1 13.27798061 -6.759649316 24.31579345 1.025199201 1.016425415 0 0.074022571 353.2176241 4797911.084 0.011386947 0.015661387 1.74E-07 6.759649316 -0.008773786 NPDDITQEEYGEFYK ddPTM_HeLa_Curcumin_4h_R1 5 NPDDITQEEYGEFYK 15 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 0 ;;;; ;;;; 284.91 8.10E-94 166914900 17737.11 13490.98 15351.94 15706.66 16421.09 16961.25 13288.19 13775.1 15185.19 12758.619 FALSE FALSE TRUE 16333.19903 14657.0802 15920.8964 15641.67 16225.27923 13443.29556 13661.02085 17975.06458 13519.41265 13201.98006 1.23717798 1.110218326 1.205947618 1.184797275 1.229003464 1.018278735 1.034770601 1.361543079 1.024044317 1 13.6884667 -9.460906795 1.157288766 0.998585373 1.171457023 0.310429423 0.095630304 0.48238809 1.140469229 0.067641962 0.016166901 3.46E-10 9.460906795 0.17287165 NPDVDTSFLPDRDREEEENR ddPTM_HeLa_Curcumin_4h_R1 1 NPDVDTSFLPDRDREEEENR 20 2 B0S8I6;Q14320;Q9Y247 B0S8I6 FAM50A;FAM50B Protein FAM50A;Protein FAM50B 0 0 46.15 0.019519 32403000 1417.9 1135 1151.9 1294.5 1615.6 1334.4 1347.9 1369.9 1258 869.13 FALSE FALSE TRUE 1305.671719 1233.104343 1194.590427 1289.143702 1596.335025 1057.630398 1385.718446 1787.576204 1120.000547 899.3322028 1.451823603 1.371133313 1.328308298 1.433445503 1.775022645 1.176017488 1.540830454 1.987670627 1.245369113 1 9.812710319 -11.18060206 0.105795191 6.84E-15 1.92121891 0.43748493 0.204038796 35.87846801 0.50264808 10.3905784 1.787600961 6.60E-12 11.18060206 1.92121891 NPDVDTSFLPDRDREEEENRLR ddPTM_HeLa_Curcumin_4h_R1 1 NPDVDTSFLPDRDREEEENRLR 22 3 B0S8I6;Q14320;Q9Y247 B0S8I6 FAM50A;FAM50B Protein FAM50A;Protein FAM50B 0 0 52.169 0.0058448 24247000 1434.8 1321.4 1498.4 1272.1 1715.3 1457.9 1364.2 1339 1387.4 1329.6 FALSE FALSE TRUE 1321.234066 1435.615928 1553.932022 1266.836387 1694.846168 1155.515106 1402.47578 1747.254936 1235.205691 1375.803501 0.960336316 1.043474542 1.129472356 0.920797473 1.231895519 0.839883824 1.019386692 1.269988726 0.897806765 1 10.42605872 -4.268246698 5.446957662 0.999701063 1.279141701 0.352401496 0.10791427 0.104212814 11.55934153 0.012887949 0.107524175 5.39E-05 4.268246698 0.279440638 NPEAALS(ph)PTFR ddPTM_HeLa_Curcumin_4h_R1 1 NPEAALSPTFR 11 0 Q86U44;B4E349;F5H6D8;B4DTN4 Q86U44 METTL3 N6-adenosine-methyltransferase 70 kDa subunit 1 0 NPEAALS(0.78)PT(0.22)FR 136.83 0.001823 26659000 1366.6 1196.8 1380.2 1175.5 1309.8 1917 1652.6 1267.3 1572.2 962.82 TRUE FALSE FALSE 1258.432168 1300.246059 1431.351426 1170.636092 1294.18149 1519.392591 1698.967508 1653.693936 1399.733593 996.2779233 1.263133648 1.305103755 1.43669893 1.175009568 1.29901653 1.525069015 1.705314821 1.659872107 1.404962973 1 9.960404445 -1 0.134788408 0.908191714 3.609690584 0.461930983 0.150547656 25.02058236 0.225252529 0.328244068 12.98011332 0.1 1 2.70149887 NPEAALSPT(ph)FR ddPTM_HeLa_Curcumin_4h_R1 1 NPEAALSPTFR 11 0 Q86U44;B4E349;F5H6D8;B4DTN4 Q86U44 METTL3 N6-adenosine-methyltransferase 70 kDa subunit 1 0 NPEAALS(0.295)PT(0.705)FR 133.98 0.0065218 49445000 1701.2 1447.8 1407.5 1517.9 1457.6 2132.4 1842.7 1169.8 1367.7 1334.2 TRUE FALSE FALSE 1566.548225 1572.941381 1459.663188 1511.619332 1440.219072 1690.116203 1894.401203 1526.466635 1217.666732 1380.563351 1.134716653 1.139347484 1.057295333 1.09492935 1.043211144 1.224222128 1.37219433 1.105683875 0.882007139 1 10.43104138 -1.000000001 0.066730717 0.83195866 1.826148086 0.431619819 0.093744252 205.7370957 1.028093491 2.869283403 19.50572421 0.1 1.000000001 0.994189425 NPEPDS(ph)DEHT(ph)PVEDEEPKK ddPTM_HeLa_Curcumin_4h_R1 2 NPEPDSDEHTPVEDEEPKK 19 1 A0A494C050;Q8N5F7 A0A494C050 NKAP NF-kappa-B-activating protein 2 0 NPEPDS(1)DEHT(1)PVEDEEPKK;NPEPDS(1)DEHT(1)PVEDEEPKK ; 78.501 0.0036527 11066400 5585 5113.2 5926.2 5647.6 7053.7 6311.8 5675.6 4506 5541.7 4595.2 TRUE FALSE FALSE 5142.941357 5555.162224 6145.830185 5624.231728 6969.589234 5002.661531 5834.842061 5879.858657 4933.789375 4754.882858 1.081612631 1.168306852 1.292530304 1.182832868 1.465775171 1.052110363 1.227126353 1.236593799 1.037625852 1 12.21519408 -7.309360926 1.468305982 1.028657 1.241944969 0.464593533 0.097704439 0.229475686 0.946541776 0.018298453 0.02129891 4.91E-08 7.309360926 0.213287969 NPLPPILGS(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 2 NPLPPILGSPTK 12 0 O75385 O75385 ULK1 Serine/threonine-protein kinase ULK1 1 0 NPLPPILGS(0.99)PT(0.01)K;NPLPPILGS(0.802)PT(0.198)K ; 119.62 0.0036047 78656000 6202.2 4649.1 4902.6 5246.5 4775.2 5415.5 3747.1 2874.8 5566.6 5461.2 TRUE FALSE FALSE 5711.289325 5050.947488 5084.294669 5224.791373 4718.258859 4292.264255 3852.233541 3751.313286 4955.957907 5650.976294 1.010673029 0.893818559 0.899719695 0.924582073 0.834945789 0.75956154 0.681693453 0.663834547 0.877009148 1 12.46428442 -5.074292377 0.465738406 1.009885473 0.53357561 0.802222872 0.050741176 0.385567059 0.090360692 0.007825771 0.088529653 8.43E-06 5.074292377 -0.476309863 NPLPSKETIEQEK ddPTM_HeLa_Curcumin_4h_R1 2 NPLPSKETIEQEK 13 1 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 0 ; ; 126.5 0.00067799 41815000 10784.8 8854.6 10032.1 10440.2 12028.9 12939.6 11440.9 11214.1 10165.6 9658.7 FALSE FALSE TRUE 9931.1717 9619.952169 10403.89845 10397.00122 11885.46322 10255.7811 11761.90086 14633.22747 9050.459113 9994.339106 0.993679682 0.962540101 1.040979132 1.040289018 1.189219527 1.026159008 1.176856292 1.464151587 0.905558538 1 13.28689545 -1 0.600499046 1.00024499 29.37860478 0.830389718 0.06285873 38.802279 0.276143062 0.009450645 1449.41513 0.1 1 28.37835979 NPNGPYPYTLK ddPTM_HeLa_Curcumin_4h_R1 2 NPNGPYPYTLK 11 0 P14866;M0QXS5;A0A3B3ITJ4;P14866-2 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 0 ; ; 134.57 0.00051072 4901900 1477.53 1147.75 1379.63 1183.78 1063.78 1884.9 1572.22 1074.61 1578.17 1035.68 FALSE FALSE TRUE 1360.581941 1246.956396 1430.760301 1178.881832 1051.095118 1493.950493 1616.332262 1402.253642 1405.048699 1071.669803 1.269590631 1.163563994 1.33507569 1.100042036 0.980801284 1.394039926 1.508237199 1.308475464 1.311083596 1 10.06564474 -13.52287875 0.069033961 0.102877124 1.61245465 0.031809823 0.160319014 205.2526793 1.101891645 30.56368556 4.516641486 3.00E-14 13.52287875 1.509577526 NPNNEFWEANRDIYLS(ph)PDR ddPTM_HeLa_Curcumin_4h_R1 1 NPNNEFWEANRDIYLSPDR 19 1 Q15696 Q15696 ZRSR2 U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 1 0 NPNNEFWEANRDIY(0.008)LS(0.992)PDR 69.98 0.0045093 6116800 1220.5 875.88 1066.9 1335.1 1109.6 1399.4 894.59 565.26 1405.4 1005.7 TRUE FALSE FALSE 1123.896137 951.5871644 1106.440253 1329.57571 1096.368745 1109.148666 919.6897877 737.6051719 1251.231136 1040.648 1.079996442 0.914417905 1.063222389 1.277642113 1.053544277 1.06582501 0.883766449 0.708794109 1.2023577 1 10.02326644 -4.483576271 2.436366456 1.051577371 0.69752997 0.584783357 0.098788353 0.190796665 1.851900753 0.012745087 0.114036346 3.28E-05 4.483576271 -0.354047401 NPPGFAFVEFEDPRDAADAVR ddPTM_HeLa_Curcumin_4h_R1 1 NPPGFAFVEFEDPRDAADAVR 21 1 P84103;P84103-2;A0A087X2D0 P84103 SRSF3 Serine/arginine-rich splicing factor 3 0 0 73.984 0.0019866 15794000 1089.9 756.62 911.28 835.73 686.21 1080 727.19 866.64 734.06 888.93 FALSE FALSE TRUE 1003.633265 822.0188614 945.0528384 832.2719707 678.0273939 855.9958259 747.5929943 1130.874546 653.5354545 919.8202513 1.091118904 0.893673367 1.027432085 0.904820229 0.737130318 0.930612068 0.812759877 1.229451673 0.710503442 1 9.845208151 -7.25614877 24.84421305 1.043028372 0.923861285 0 0.163517826 531.5504436 2496112.984 0.020150693 0.024284207 5.54E-08 7.25614877 -0.119167087 NPPGFAFVEFEDPRDAEDAVR ddPTM_HeLa_Curcumin_4h_R1 1 NPPGFAFVEFEDPRDAEDAVR 21 1 Q16629-4;Q16629;A0A0B4J1Z1;C9JAB2;Q16629-3;Q16629-2 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 0 0 79.695 0.0010423 22686000 362.21 258.5 220.37 298.39 213.73 389.07 156.74 232.43 303.43 297.55 FALSE FALSE TRUE 333.5406963 280.8435881 228.5371061 297.1553412 211.1814093 308.3724963 161.1377026 303.296837 270.1444881 307.8898404 1.083311797 0.912156074 0.742269072 0.96513526 0.685899246 1.001567625 0.523361545 0.985082316 0.877406308 1 8.266270452 -7.037241003 4.28484746 1.038636002 0.81314451 0.184091775 0.149416392 0.157754951 6.467549029 0.020817308 0.026295309 9.18E-08 7.037241003 -0.225491491 NPPVIPVLQEIYK(ac)GEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 NPPVIPVLQEIYKGEKK 17 2 Q5VYS8-4;Q5VYS8;X6R3Q3 Q5VYS8-4 ZCCHC6 Terminal uridylyltransferase 7 0 2 NPPVIPVLQEIYK(1)GEK(1)K 51.193 0.020084 3747200 2081.9 2350 1983.6 2130.3 2059.2 3093.7 2927 3159.8 2494.5 2198.6 FALSE TRUE FALSE 1917.115418 2553.123529 2057.113961 2121.485383 2034.645385 2452.031747 3009.123742 4123.208474 2220.859591 2275.001186 0.842687656 1.122251515 0.904225445 0.932520561 0.894349153 1.07781559 1.322691065 1.812398384 0.976201509 1 11.15165158 -4.301457699 1.358730497 0.935433357 2.144895338 0.926596206 0.074541865 0.232788288 0.391661294 0.012064903 0.377544069 5.00E-05 4.301457699 1.20946198 NPQAGVPPFSSLK(ac)GK ddPTM_HeLa_Curcumin_4h_R1 2 NPQAGVPPFSSLKGK 15 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 0 1 ; NPQAGVPPFSSLK(1)GK;NPQAGVPPFSSLK(1)GK 158.11 0.0009914 2877530 3117.22 2550.18 2669.8 2374.49 3454.23 3536.18 2072.92 1718.93 2087.32 2137.69 FALSE TRUE FALSE 2870.488748 2770.606196 2768.745137 2364.66499 3413.040563 2802.736407 2131.080556 2243.023844 1858.346218 2211.974568 1.297704227 1.252548847 1.251707491 1.069029013 1.542983636 1.267074426 0.96342905 1.014036904 0.840130011 1 11.11111908 -4.752198592 24.90221488 1.189731703 0.988732879 0.166774293 0.180078623 242.389971 653181.0706 0.023537312 0.085647032 1.77E-05 4.752198592 -0.200998824 NPQMPQYSSPQPGSALS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 NPQMPQYSSPQPGSALSPR 19 0 O14497;O14497-2;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497 ARID1A AT-rich interactive domain-containing protein 1A 1 0 NPQMPQYSSPQPGS(0.02)ALS(0.98)PR;NPQMPQYSSPQPGS(0.02)ALS(0.98)PR ; 191.61 7.25E-10 39757000 4671.6 4243.97 4046.37 4676.5 4194.75 4606.9 3322.79 2521.7 4752.8 4268.3 TRUE FALSE FALSE 4301.837931 4610.799856 4196.332032 4657.149882 4144.730346 3651.37701 3416.018545 3290.554722 4231.429731 4416.623107 0.974010647 1.04396498 0.950122283 1.05445943 0.938438768 0.826735024 0.773445789 0.745038606 0.958069011 1 12.10872801 -5.200776735 2.090240946 0.993463122 0.75913142 0.897283515 0.032971218 0.062918137 0.526395013 0.004277174 0.013862437 6.30E-06 5.200776735 -0.234331702 NSDLLT(ph)SPDVGLLK ddPTM_HeLa_Curcumin_4h_R1 4 NSDLLTSPDVGLLK 14 0 P05412 P05412 JUN Transcription factor AP-1 1 0 NSDLLT(0.991)S(0.009)PDVGLLK;NSDLLT(0.916)S(0.084)PDVGLLK;NS(0.005)DLLT(0.928)S(0.067)PDVGLLK;NSDLLT(0.784)S(0.216)PDVGLLK ;;; 244.18 2.37E-28 138154000 16093.3 13468.5 13727.4 13896.1 14850.8 24395.7 25359.1 96948 17090.5 13786.1 TRUE FALSE FALSE 14819.49832 14632.65713 14236.14952 13838.60162 14673.71391 19335.75682 26070.6081 126506.9989 15215.71491 14265.16595 1.038859161 1.025761437 0.997965924 0.970097486 1.028639552 1.355452638 1.827571315 8.868245863 1.066634273 1 13.80020891 -4.247891991 3.342882751 1.040337505 10.04087085 0.997702989 0.111684663 0.013573855 0.241465103 0.019797808 0.31723525 5.65E-05 4.247891991 9.000533343 up NPQNSSQSADGLR ddPTM_HeLa_Curcumin_4h_R1 1 NPQNSSQSADGLR 13 0 P0DN76;Q01081 P0DN76 U2AF1 Splicing factor U2AF 35 kDa subunit 0 0 152.38 0.00016636 933360 226.28 218.37 114.81 151.08 210.26 341.23 266.05 264.29 233.36 187.74 FALSE FALSE TRUE 208.3696992 237.2449298 119.0649596 150.454871 207.7527868 270.4550515 273.514647 344.8708044 207.7609918 194.263951 1.072611249 1.22125041 0.612903006 0.774486827 1.069435609 1.39220401 1.407953691 1.775269176 1.069477846 1 7.601874399 -4.873702803 1.476618516 0.998337743 1.706691839 0.687865119 0.175885239 0.235057957 0.868069606 0.027097265 0.174174072 1.34E-05 4.873702803 0.708354096 NPRVS(ph)RVTVQLEMK ddPTM_HeLa_Curcumin_4h_R1 1 NPRVSRVTVQLEMK 14 2 O75333 O75333 TBX10 T-box transcription factor TBX10 1 0 NPRVS(0.995)RVT(0.005)VQLEMK 75.143 0.018339 20543000 4125.2 3469.7 3419.1 3638.9 3131.4 5215 3961.7 3642.4 3647.8 3503.6 TRUE FALSE FALSE 3798.686067 3769.605407 3545.814854 3623.843196 3094.0601 4133.350215 4072.85464 4752.950992 3247.645466 3625.349839 1.047812276 1.039790799 0.978061432 0.999584414 0.853451456 1.140124512 1.123437687 1.31103237 0.895815745 1 11.8239045 -4.424450731 1.506725813 1.011072774 1.361808348 0.653515363 0.072846027 0.358837398 0.935807298 0.00907651 0.169664119 3.76E-05 4.424450731 0.350735573 AEAPAGPALGLPS(ph)PEAESGVDRGEPEPMEVEEGELEIVPVRR ddPTM_HeLa_Curcumin_4h_R1 1 AEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRR 42 2 Q53F19 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 0 AEAPAGPALGLPS(0.5)PEAES(0.5)GVDRGEPEPMEVEEGELEIVPVRR 76.972 4.18E-08 108200000 1140.5 934.68 960.26 1095 1121.9 1326.9 1271 1924.3 1278.8 1061.4 TRUE FALSE FALSE 1050.228222 1015.469574 995.8480803 1090.46918 1108.522075 1051.685983 1306.660839 2511.010212 1138.518839 1098.283571 0.956245044 0.92459689 0.906731291 0.992884906 1.009322278 0.957572352 1.189729933 2.286304082 1.036634681 1 10.10103488 -4.247261522 2.742371059 0.972111256 2.563710918 0.990527922 0.038333901 0.029266625 0.285451604 0.005248725 0.106445229 5.66E-05 4.247261522 1.591599662 up NPT(ph)FILLCLAGATEATLIT(ph)GMS(ph)T(ph)FSPK ddPTM_HeLa_Curcumin_4h_R1 1 NPTFILLCLAGATEATLITGMSTFSPK 27 0 E1P5H9;Q96BD0-3;Q96BD0-4;Q96BD0 E1P5H9 SLCO4A1 Solute carrier organic anion transporter family member 4A1 4 0 NPT(0.996)FILLCLAGAT(0.027)EAT(0.193)LIT(0.79)GMS(0.791)T(0.791)FS(0.411)PK 43.233 0.0079315 0 383.08 363.78 231.64 266.39 335.49 158.29 215.14 265.21 625.65 407.3 TRUE FALSE FALSE 352.7588138 395.2235222 240.2247822 265.2877488 331.4895009 125.4588697 221.1762494 346.0713081 557.0177603 421.4536447 0.837005014 0.937762734 0.569990995 0.629458903 0.786538461 0.297681302 0.524793775 0.821137301 1.321658425 1 8.719230149 -6.909397714 0.671076287 0.95706597 0.563676735 0.508335824 0.190181993 0.388145391 0.36247711 0.037946244 0.05813262 1.23E-07 6.909397714 -0.393389235 NPVSLPSLPNPTKPNNVPSVPS(ph)PSIQR ddPTM_HeLa_Curcumin_4h_R1 1 NPVSLPSLPNPTKPNNVPSVPSPSIQR 27 1 Q6VMQ6-2;Q6VMQ6-5;Q6VMQ6;Q6VMQ6-4 Q6VMQ6-2 ATF7IP Activating transcription factor 7-interacting protein 1 1 0 NPVSLPSLPNPT(0.001)KPNNVPS(0.094)VPS(0.68)PS(0.225)IQR 73.164 0.00012866 11806000 438.95 216.7 357.19 550.34 336.59 658.05 712.35 632.13 578.35 462.1 TRUE FALSE FALSE 404.2066443 235.4305824 370.4277756 548.0628389 332.5763841 521.5630122 732.3366238 824.863527 514.906452 478.1579406 0.845341277 0.49236991 0.77469753 1.146196251 0.695536675 1.090775595 1.531578923 1.725085912 1.076854337 1 8.901343424 -4.774970703 2.544867515 0.883104641 1.697681015 0.738721352 0.181051897 0.107881406 1.359042487 0.025526195 0.119232111 1.68E-05 4.774970703 0.814576374 NPYLLS(ph)EEEDDDVDGDVNVEK ddPTM_HeLa_Curcumin_4h_R1 2 NPYLLSEEEDDDVDGDVNVEK 21 0 G3V5V3;O60524-4;O60524-5;O60524-3;O60524 G3V5V3 NEMF Nuclear export mediator factor NEMF 1 0 NPYLLS(1)EEEDDDVDGDVNVEK;NPYLLS(1)EEEDDDVDGDVNVEK ; 171.89 5.00E-09 10531600 9093.7 7845.9 8345.5 9189.4 10161.2 9531.1 8580.9 6690.5 8893.3 7548.2 TRUE FALSE FALSE 8373.924049 8524.064635 8654.791571 9151.376698 10040.03433 7554.242422 8821.65696 8730.402651 7917.72724 7810.499388 1.072136829 1.091359747 1.108097081 1.171676258 1.285453571 0.967190707 1.129461321 1.117777778 1.013728681 1 12.93119908 -7.837026477 0.710596198 1.011119848 1.130519272 0.292353351 0.073589086 0.548795624 0.615109004 0.024978684 0.019848459 1.46E-08 7.837026477 0.119399423 NPYLLS(ph)EEEDDDVDGDVNVEKNETEPPK ddPTM_HeLa_Curcumin_4h_R1 1 NPYLLSEEEDDDVDGDVNVEKNETEPPK 28 1 G3V5V3;O60524-4;O60524-5;O60524-3;O60524 G3V5V3 NEMF Nuclear export mediator factor NEMF 1 0 NPYLLS(1)EEEDDDVDGDVNVEKNETEPPK 99.997 2.98E-08 5316500 2365.9 1638.7 1558.2 2215.7 2008.2 2333.1 1885.4 1422.1 2342.2 1895.8 TRUE FALSE FALSE 2178.636519 1780.341926 1615.948263 2206.53202 1984.253527 1849.188761 1938.29925 1855.691743 2085.26652 1961.678909 1.110597921 0.907560314 0.82375778 1.124818139 1.011507805 0.942656187 0.988081811 0.945971196 1.063000938 1 10.9378732 -7.261589655 24.99985725 1.052226795 0.966303133 0.240396201 0.076575556 16.89100276 2809805.427 0.013973385 0.016510687 5.48E-08 7.261589655 -0.085923663 NPYLLS(ph)EEEDDDVDGDVNVEKNETEPPKGK ddPTM_HeLa_Curcumin_4h_R1 2 NPYLLSEEEDDDVDGDVNVEKNETEPPKGK 30 2 G3V5V3;O60524-4;O60524-5;O60524-3;O60524 G3V5V3 NEMF Nuclear export mediator factor NEMF 1 0 NPY(0.001)LLS(0.998)EEEDDDVDGDVNVEKNETEPPKGK;NPY(0.002)LLS(0.997)EEEDDDVDGDVNVEKNET(0.001)EPPKGK ; 49.464 0.0045081 80469000 7010.1 5128.3 5134.7 6796.5 5846 7107.7 5233.5 3965.1 8049.7 6054.8 TRUE FALSE FALSE 6455.243188 5571.567401 5324.996499 6768.377884 5776.290268 5633.4829 5380.337925 5174.040737 7166.668049 6265.203849 1.030332507 0.889287489 0.849931882 1.080312476 0.921963659 0.899169929 0.858765023 0.825837572 1.143884257 1 12.61314574 -1.526116061 0.252844781 1.019285296 5.03E-11 0.446446906 0.07599677 24.46440672 0.388571871 0.036146189 10.2135241 0.029777206 1.526116061 -1.019285296 NQAIYAAVDDDDDDAA ddPTM_HeLa_Curcumin_4h_R1 1 NQAIYAAVDDDDDDAA 16 0 Q9UK59-2;Q9UK59 Q9UK59-2 DBR1 Lariat debranching enzyme 0 0 114.82 0.010763 26036000 9299.5 7852.1 7482.5 7995.6 7822.6 8869.1 7443 7268.3 8373.6 7663 FALSE FALSE TRUE 8563.434762 8530.800536 7759.808032 7962.516326 7729.320604 7029.548685 7651.830548 9484.371211 7455.03703 7929.28868 1.079975154 1.075859498 0.978625996 1.004190495 0.974781083 0.886529545 0.965008446 1.196118794 0.940189887 1 12.95297574 -6.746399384 24.93147236 1.041678284 0.993012389 0 0.082892287 478.5836585 793335.95 0.012301154 0.017355066 1.79E-07 6.746399384 -0.048665894 NQATSATSEKDNDDDQS(ph)DKGTYTIELENPNSEEVEAR ddPTM_HeLa_Curcumin_4h_R1 2 NQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEAR 37 2 H0Y2V6;Q5SW79;H0YB66 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 0 NQAT(0.001)S(0.002)AT(0.001)S(0.001)EKDNDDDQS(0.335)DKGT(0.335)Y(0.271)T(0.054)IELENPNSEEVEAR;NQATSAT(0.001)S(0.001)EKDNDDDQS(0.915)DKGT(0.061)Y(0.017)T(0.006)IELENPNSEEVEAR ; 90.303 2.14E-10 153008000 4573.2 3371.72 3914.72 3914.2 3484.6 4405.3 3289.1 3063.38 4735 3904.44 TRUE FALSE FALSE 4211.226394 3663.156453 4059.802967 3898.004078 3443.048421 3491.591122 3381.383294 3997.39046 4215.582346 4040.118999 1.042352068 0.906695187 1.004872126 0.964824075 0.852214606 0.864229772 0.83695141 0.98942394 1.043430242 1 11.98018207 -6.26215207 1.082349764 1.015825907 0.88131552 0.476316617 0.054209009 0.278527002 0.645291837 0.009279737 0.019085813 5.47E-07 6.26215207 -0.134510388 NQDT(ph)RMT(ph)S(ph)RLK ddPTM_HeLa_Curcumin_4h_R1 1 NQDTRMTSRLK 11 2 A0A0J9YXH5;A0A0J9YXQ4 A0A0J9YXH5 3 0 NQDT(1)RMT(1)S(1)RLK 74.537 0.014002 5746200 2164.9 1895 2179 2099.4 3079.5 2317 1860.2 2172.7 1774.6 2180.7 TRUE FALSE FALSE 1993.545881 2058.795356 2259.755657 2090.713239 3042.778974 1836.428082 1912.392206 2835.146228 1579.93082 2256.479163 0.883476308 0.912392806 1.001452038 0.9265378 1.348463139 0.813846683 0.847511573 1.256446891 0.700175231 1 11.13985774 NQEASLGMKT(ph)PEAPAHSEKPR ddPTM_HeLa_Curcumin_4h_R1 1 NQEASLGMKTPEAPAHSEKPR 21 2 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 1 0 NQEAS(0.017)LGMKT(0.983)PEAPAHSEKPR 54.457 0.0050023 8881000 3900.7 3733.6 3584.6 3839.9 3600.1 3903.8 3674.9 1955.7 3993.4 3625.1 TRUE FALSE FALSE 3591.955479 4056.315747 3717.448429 3824.011511 3557.171159 3094.107875 3778.007804 2551.983927 3555.334011 3751.071955 0.957581065 1.081375083 0.991036289 1.01944499 0.948307897 0.824859643 1.00718084 0.68033457 0.947818131 1 11.87308722 -3.558163338 0.98067538 0.986359467 1.55E-39 0.612865772 0.067532007 3.263578212 0.900526951 0.009611068 4.749651327 0.00027659 3.558163338 -0.986359467 NQEKY(ph)DK ddPTM_HeLa_Curcumin_4h_R1 1 NQEKYDK 7 1 Q9UHK0 Q9UHK0 NUFIP1 Nuclear fragile X mental retardation-interacting protein 1 1 0 NQEKY(1)DK 108.09 0.0046958 0 1412.5 1361.2 1397.3 1479.8 1635.1 1880.8 1409.8 1371.9 1703.5 1489.9 TRUE FALSE FALSE 1300.699135 1478.856063 1449.085167 1473.67698 1615.6025 1490.700879 1449.355194 1790.185995 1516.630312 1541.673914 0.84369277 0.959253477 0.939942717 0.955894088 1.047953452 0.966936565 0.940117868 1.161196267 0.983755578 1 10.59028193 -5.935391188 4.188334337 0.928801536 1.018079152 0.234440994 0.068236235 0.252957072 8.952012689 0.011498849 0.021241497 1.16E-06 5.935391188 0.089277617 NQGETPTTEVPAPFFLPASLS(ph)ANNTPTR ddPTM_HeLa_Curcumin_4h_R1 1 NQGETPTTEVPAPFFLPASLSANNTPTR 28 0 Q9UJX2;Q9UJX2-3 Q9UJX2 CDC23 Cell division cycle protein 23 homolog 1 0 NQGETPTTEVPAPFFLPAS(0.177)LS(0.549)ANNT(0.216)PT(0.058)R 79.112 6.37E-06 3077700 853.81 659.59 773.78 915.02 678.37 603.07 422.16 457.02 910.99 986.42 TRUE FALSE FALSE 786.2300376 716.6020205 802.4569675 911.2338897 670.2808808 477.986484 434.0046734 596.3632941 811.0566762 1020.698022 0.770286628 0.702070549 0.786184504 0.892755615 0.656688723 0.46829373 0.425203796 0.58427006 0.794609825 1 9.995340386 -4.583866415 0.154920284 1.086436286 7.50E-19 0.580423773 0.110744328 8.269132027 0.249601251 0.319919299 1.896736504 2.61E-05 4.583866415 -1.086436286 NQGGGLSSS(ph)GAGEGQGPK ddPTM_HeLa_Curcumin_4h_R1 1 NQGGGLSSSGAGEGQGPK 18 0 P07814 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 0 NQGGGLS(0.254)S(0.254)S(0.492)GAGEGQGPK 165.9 1.66E-05 4906600 2542.9 1730.8 2338.1 1934.3 2210.4 3023.4 2602.7 1510.6 2095.7 2104.9 TRUE FALSE FALSE 2341.626782 1880.40264 2424.752043 1926.296379 2184.042424 2396.312759 2675.724757 1971.174986 1865.806953 2178.045118 1.075104809 0.863344209 1.113269887 0.884415278 1.002753527 1.100212635 1.228498315 0.905020272 0.856642931 1 11.08881812 -5.258885081 24.01989632 1.015466627 1.092969204 0.066393616 0.115242827 224.97878 2115599.585 0.013750178 0.033309497 5.51E-06 5.258885081 0.077502577 NQGGYDRYS(ph)GGNYRDNYDN ddPTM_HeLa_Curcumin_4h_R1 2 NQGGYDRYSGGNYRDNYDN 19 2 P98179 P98179 RBM3 RNA-binding protein 3 1 0 NQGGY(0.006)DRY(0.003)S(0.988)GGNY(0.003)RDNYDN;NQGGY(0.001)DRY(0.021)S(0.949)GGNY(0.029)RDNYDN ; 77.681 0.0038718 89348000 3859.8 2810.15 2856 3598.7 2812.5 4775.3 3679.8 1996.05 4025.3 4104 TRUE FALSE FALSE 3554.292757 3053.046844 2961.845872 3583.809533 2778.962774 3784.848951 3783.045284 2604.636456 3583.734661 4246.613695 0.836971058 0.718936796 0.697460632 0.84392172 0.654395001 0.891262833 0.890838102 0.613344336 0.843904089 1 12.05209716 -8.393011556 0.747225011 0.987520142 0.766670923 0.233956019 0.101664505 0.376144669 0.443693775 0.039428554 0.02073279 4.05E-09 8.393011556 -0.220849218 NQGGYDRYSGGNYRDNY(ph)DN ddPTM_HeLa_Curcumin_4h_R1 1 NQGGYDRYSGGNYRDNYDN 19 2 P98179 P98179 RBM3 RNA-binding protein 3 1 0 NQGGYDRY(0.001)S(0.001)GGNY(0.045)RDNY(0.954)DN 86.467 0.0024596 9374700 3030.4 2335.6 2154.7 2827.6 2821.8 4731.8 3523.1 1551.3 3678.7 3079.1 TRUE FALSE FALSE 2790.540642 2537.478857 2234.555077 2815.90014 2788.151878 3750.371342 3621.948704 2024.284229 3275.155814 3186.098496 0.875848831 0.796421975 0.70134526 0.883808251 0.875099085 1.177104646 1.136797468 0.635348917 1.027951841 1 11.63757515 -4.23007872 23.55128389 0.931846465 0.635347782 0.298698548 0.140061387 6542.968509 4913473.675 0.020260814 3.347043352 5.89E-05 4.23007872 -0.296498683 NQGGYGGSS(ph)SSSSYGSGR ddPTM_HeLa_Curcumin_4h_R1 1 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 1 0 NQGGYGGS(0.079)S(0.306)S(0.306)S(0.306)S(0.002)SYGSGR 290.92 2.26E-81 205450000 2957.7 2925.6 2345 2945.7 2689.9 3810.4 3799.3 3334.8 3413.6 3107.9 TRUE FALSE FALSE 2723.594924 3178.475828 2431.907763 2933.511474 2657.824699 3020.080088 3905.898133 4351.565168 3039.13662 3215.899294 0.846915489 0.988362986 0.756213905 0.912190092 0.826463908 0.939109037 1.214558597 1.353140995 0.945034761 1 11.65100651 -4.671306747 2.941746114 0.909205257 1.333922654 0.826676337 0.071329302 0.086925872 1.43635922 0.011432353 0.056509517 2.13E-05 4.671306747 0.424717397 NQGGYGGSSS(ph)SSSYGSGR ddPTM_HeLa_Curcumin_4h_R1 1 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 1 0 NQGGYGGS(0.056)S(0.056)S(0.694)S(0.179)S(0.015)SYGSGR 300.87 1.56E-96 187600000 1909.2 1981.8 1948.8 1953.3 2041.8 2582.8 2290.1 2192.9 2446.9 1811.1 TRUE FALSE FALSE 1758.084805 2153.097961 2021.024242 1945.217762 2017.452869 2047.098166 2354.354043 2861.505115 2178.481192 1874.03559 0.938127757 1.148909857 1.078434291 1.037983362 1.076528578 1.092347539 1.25630167 1.526921436 1.162454546 1 10.87193264 -1 0.525190982 0.987126459 21.34265665 0.739745596 0.079687393 26.45176991 0.237379699 0.012305465 604.3062117 0.1 1 20.35553019 NQGGYGGSSSS(ph)SSYGSGR ddPTM_HeLa_Curcumin_4h_R1 1 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 1 0 NQGGYGGS(0.064)S(0.064)S(0.191)S(0.572)S(0.107)SYGSGR 99.371 0.0015732 2283300 1121.3 961.19 1144.3 1013.8 1013 1321.3 1124.9 1155.6 1118 924.77 TRUE FALSE FALSE 1032.547922 1044.270981 1186.708765 1009.605164 1000.920637 1047.247486 1156.461666 1507.93712 995.3581971 956.9056887 1.079048786 1.091299794 1.240152273 1.0550728 1.045997164 1.094410346 1.208542995 1.575847169 1.04018422 1 9.902232931 -4.151013598 1.602863292 1.059519563 1.874079943 0.850938571 0.062059509 0.401735742 0.783004207 0.010198246 0.550756383 7.06E-05 4.151013598 0.81456038 NQGGYGGSSSSSS(ph)YGSGR ddPTM_HeLa_Curcumin_4h_R1 1 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 1 0 NQGGYGGSSSSS(0.042)S(0.958)YGSGR 190.55 7.33E-09 1356400 840.43 776.96 649.66 664.83 627.18 680.13 981.42 658.18 916.08 489.61 TRUE FALSE FALSE 773.9090787 844.1169603 673.7369711 662.0791096 619.7012881 539.0633714 1008.956004 858.8560521 815.5883159 506.6239111 1.527581036 1.666160917 1.329856243 1.306845364 1.223197868 1.064030654 1.991528591 1.695253685 1.60984963 1 8.984771359 -9.245038119 0.876035716 0.986338136 1.468697802 0 0.314255235 0.642410205 0.84762253 0.206197048 0.051000699 5.69E-10 9.245038119 0.482359666 HQNS(ph)LPELEAAEAGAPGSGPVDLFR ddPTM_HeLa_Curcumin_4h_R1 2 HQNSLPELEAAEAGAPGSGPVDLFR 25 0 Q96BZ8 Q96BZ8 LENG1 Leukocyte receptor cluster member 1 1 0 HQNS(1)LPELEAAEAGAPGSGPVDLFR;HQNS(1)LPELEAAEAGAPGSGPVDLFR ; 106.76 1.44E-07 20998600 2509.4 1536.65 1952.7 2399.4 1773.04 3254.2 4255.1 15472.2 1512.04 2166.97 TRUE FALSE FALSE 2310.778342 1669.471179 2025.06878 2389.471919 1751.897656 2579.242238 4374.486654 20189.60255 1346.172995 2242.272046 1.030552179 0.744544437 0.903132509 1.065647642 0.781304686 1.150280691 1.950917 9.004082528 0.600361137 1 11.13074561 -4.24716556 3.13036095 0.987322523 10.36547442 0.994708847 0.175942783 0.015279986 0.221073674 0.020535354 0.35681595 5.66E-05 4.24716556 9.378151899 up NQGGYGGSSSSSSYGSGR ddPTM_HeLa_Curcumin_4h_R1 6 NQGGYGGSSSSSSYGSGR 18 0 F8W6I7;P09651-2;P09651;P09651-3;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 0 0 ;;;;; ;;;;; 377.85 8.04E-291 54646800 3155.56 2594.5 2839.23 2658.24 3160.036 3868.84 3179.48 2791.03 3263.83 2889.22 FALSE FALSE TRUE 2905.794096 2818.757019 2944.454361 2647.240907 3122.354635 3066.398973 3268.687652 3642.002199 2905.796015 2989.62018 0.971960959 0.94284787 0.984892456 0.885477334 1.044398434 1.025681789 1.09334546 1.218215686 0.9719616 1 11.54574649 -4.25235759 1.067665927 0.977906648 1.342546916 0.813571602 0.037447137 0.570996422 0.502008087 0.00567729 0.236529154 5.59E-05 4.25235759 0.364640267 NQGIEGS(ph)PGGR ddPTM_HeLa_Curcumin_4h_R1 1 NQGIEGSPGGR 11 0 Q6ZUT6-4;Q6ZUT6;H0YM82;Q6ZUT6-3 Q6ZUT6-4 C15orf52 Uncharacterized protein C15orf52 1 0 NQGIEGS(1)PGGR 106.79 0.0078994 18350000 2339.5 2143.7 2236.1 2344.3 2188.3 2865.1 1895.3 1367.4 2548.7 1909.7 TRUE FALSE FALSE 2154.326106 2328.991876 2318.971833 2334.599908 2162.205952 2270.845964 1948.477017 1784.313965 2269.113987 1976.061933 1.090211835 1.178602673 1.17353196 1.181440657 1.094199486 1.149177526 0.98604046 0.902964596 1.148301047 1 10.94841245 -4.545978662 4.967823801 1.081767599 0.919278067 0.475833018 0.066353513 0.143028694 9.26460499 0.011407444 0.05032972 2.84E-05 4.545978662 -0.162489531 NQK(ac)LTATTQK ddPTM_HeLa_Curcumin_4h_R1 2 NQKLTATTQK 10 1 P12270 P12270 TPR Nucleoprotein TPR 0 1 ; NQK(1)LTATTQK;NQK(1)LTATTQK 206.49 1.68E-26 54528000 12233.5 9740.6 10412.2 10339 10611.8 12721.9 12157.8 10896.1 10810 9635.9 FALSE TRUE FALSE 11265.20557 10582.53406 10798.08529 10296.21996 10485.26122 10083.23453 12498.91515 14218.27073 9624.170045 9970.746808 1.129825657 1.061358218 1.082976581 1.032642806 1.051602394 1.011281775 1.253558574 1.425998574 0.965240642 1 13.28348585 -4.529898505 3.049508329 1.05874227 1.415445181 0.870591248 0.047645064 0.072998594 1.279880297 0.007268329 0.045956666 2.95E-05 4.529898505 0.356702912 NQKPSQVNGAPGS(ph)PTEPAGQK ddPTM_HeLa_Curcumin_4h_R1 4 NQKPSQVNGAPGSPTEPAGQK 21 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 0 NQKPSQVNGAPGS(0.999)PT(0.001)EPAGQK;NQKPSQVNGAPGS(0.904)PT(0.096)EPAGQK;NQKPSQVNGAPGS(0.998)PT(0.002)EPAGQK;NQKPSQVNGAPGS(0.993)PT(0.007)EPAGQK ;;; 153.34 1.15E-06 517400000 42925.3 35566.7 43383.9 45358.9 42284.3 49595.4 40723 27086.6 42563.5 39116.4 TRUE FALSE FALSE 39527.71721 38640.92707 44991.7455 45171.21689 41780.08734 39308.75498 41865.57778 35345.17965 37894.39054 40475.69199 0.976579158 0.954669955 1.111574461 1.116008515 1.032226635 0.971169437 1.034338778 0.873244605 0.936225885 1 15.30476813 -4.253998257 24.12289291 1.007067287 0.873244499 0.338380681 0.058479725 518.6213368 1681215.444 0.008113178 0.110059483 5.57E-05 4.253998257 -0.133822787 NQKQPGVDSLS(ph)PVASLPK ddPTM_HeLa_Curcumin_4h_R1 2 NQKQPGVDSLSPVASLPK 18 1 A0A087X151;Q9UBW7-2;Q9UBW7 A0A087X151 ZMYM2 Zinc finger MYM-type protein 2 1 0 NQKQPGVDS(0.013)LS(0.985)PVAS(0.002)LPK;NQKQPGVDSLS(0.993)PVAS(0.007)LPK ; 119.27 0.00016755 37800000 4829.4 3821.5 3760.2 4353 3433.4 6114.7 5838.7 6190.9 5235.9 4761.7 TRUE FALSE FALSE 4447.147894 4151.813432 3899.55632 4334.988439 3392.458947 4846.442293 6002.518208 8078.476911 4661.53487 4927.168721 0.902576743 0.842636749 0.791439575 0.879813273 0.688520962 0.983616062 1.218248968 1.639577893 0.946087933 1 12.26654316 -4.413385893 1.98432833 0.909392722 1.732172158 0.875480267 0.089821959 0.162463777 0.856607 0.015126733 0.215543968 3.86E-05 4.413385893 0.822779436 NQLTSNPENTVFDAK ddPTM_HeLa_Curcumin_4h_R1 2 NQLTSNPENTVFDAK 15 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 0 ; ; 318.49 3.45E-154 4009900 1212.36 1057.98 1238.54 1082.82 1281.96 1203.02 802.38 690.59 1088 1075.31 FALSE FALSE TRUE 1116.400427 1149.427077 1284.441382 1078.339578 1266.673464 953.5000912 824.8926233 901.1477119 968.649122 1112.676942 1.00334642 1.033028576 1.154370449 0.969139861 1.138401827 0.856942437 0.741358603 0.809891602 0.870557378 1 10.11981906 -5.058103692 5.554794843 1.020962492 0.779900319 0.639528084 0.077682476 0.072165604 4.725309303 0.008473882 0.022617979 8.75E-06 5.058103692 -0.241062172 NQNYLVPS(ph)PVLR ddPTM_HeLa_Curcumin_4h_R1 2 NQNYLVPSPVLR 12 0 C9J3R1;C9IZP0;J3KR59;J3KR68;Q9UID6 C9J3R1 ZNF639 Zinc finger protein 639 1 0 NQNYLVPS(1)PVLR;NQNYLVPS(1)PVLR ; 162.72 0.00015131 24413000 6292.6 5112.2 5577.6 5650.8 4901.9 6211.9 4896.5 2711.86 6741.4 5555 TRUE FALSE FALSE 5794.53407 5554.075788 5784.310763 5627.418487 4843.448044 4923.481917 5033.882612 3538.69363 6001.885286 5748.035837 1.008089413 0.966256291 1.006310839 0.979015902 0.842626626 0.856550317 0.875756999 0.615635276 1.044162816 1 12.48885334 -3.37865591 0.487586239 1.005129047 1.12E-17 0.857556724 0.045798679 2.224490566 0.190384113 0.008690194 1.556825186 0.000418162 3.37865591 -1.005129047 NQPTVYIAASPPNT(ph)DELMSR ddPTM_HeLa_Curcumin_4h_R1 2 NQPTVYIAASPPNTDELMSR 20 0 A0A1B0GV57;Q9NYJ8-2;Q9NYJ8 A0A1B0GV57 TAB2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 1 0 NQPTVYIAAS(0.051)PPNT(0.742)DELMS(0.206)R;NQPTVY(0.017)IAAS(0.067)PPNT(0.913)DELMS(0.002)R ; 110.25 0.0064742 45883000 3277.5 3007.2 3328.1 3365.5 3017.5 3749.5 2924.18 1839.59 3789.8 2979.5 TRUE FALSE FALSE 3018.082417 3267.128968 3451.442314 3351.574453 2981.518283 2971.811434 3006.224621 2400.472523 3374.068422 3083.037403 0.978931496 1.059711103 1.119494142 1.087101457 0.96707172 0.96392325 0.975085355 0.778606358 1.094397498 1 11.59013668 -3.558932889 1.202044759 1.009887068 8.96E-13 0.630078184 0.056648091 3.73262714 1.317938273 0.008483839 7.11578516 0.0002761 3.558932889 -1.009887068 NQS(ph)LVEENEK ddPTM_HeLa_Curcumin_4h_R1 2 NQSLVEENEK 10 0 O95239;O95239-2;Q2VIQ3 O95239 KIF4A;KIF4B Chromosome-associated kinesin KIF4A;Chromosome-associated kinesin KIF4B 1 0 NQS(1)LVEENEK;NQS(1)LVEENEK ; 142.39 0.0013581 120001000 5599.1 5404.6 5276.4 5704.6 5327.4 5380.2 3338.2 2040.6 5741.8 5065.5 TRUE FALSE FALSE 5155.925327 5871.749542 5471.948026 5680.995877 5263.874234 4264.285873 3431.860908 2662.769546 5111.938905 5241.525748 0.983668797 1.120236707 1.043960917 1.083843932 1.004263737 0.813558127 0.654744644 0.508014207 0.975276885 1 12.35577111 -4.831883241 1.644465943 1.014596825 0.513219465 0.935146775 0.047936379 0.086226925 0.40785796 0.00783135 0.048571822 1.47E-05 4.831883241 -0.50137736 NQS(ph)LVEENEKLSR ddPTM_HeLa_Curcumin_4h_R1 1 NQSLVEENEKLSR 13 1 O95239;O95239-2;Q2VIQ3 O95239 KIF4A;KIF4B Chromosome-associated kinesin KIF4A;Chromosome-associated kinesin KIF4B 1 0 NQS(1)LVEENEKLSR 102.03 0.0019791 0 2306 1824.9 1982.5 2572.1 1457.4 2449.3 1024 664.93 3689.2 2591.8 TRUE FALSE FALSE 2123.477667 1982.636224 2055.973194 2561.457332 1440.021457 1941.287571 1052.730684 867.664096 3284.50399 2681.864857 0.791791451 0.739275217 0.76662073 0.95510306 0.536947808 0.723857343 0.392536813 0.323530134 1.224708986 1 11.38902082 -4.466048222 0.349435535 0.933511652 5.77E-34 0.694714818 0.144881662 2.188563156 0.207170244 0.040453124 0.841752291 3.42E-05 4.466048222 -0.933511652 NQS(ph)PVLEPVGR ddPTM_HeLa_Curcumin_4h_R1 2 NQSPVLEPVGR 11 0 B4DG22;B1AXG1;B7ZB17;P51812;A0A2R8Y603 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 0 NQS(1)PVLEPVGR;NQS(1)PVLEPVGR ; 133.04 0.0023898 200500000 2917.5 2565.8 2058.78 2466.44 2324.54 3468.6 2387.65 1407.39 3009.4 2501.7 TRUE FALSE FALSE 2686.576796 2787.576319 2135.080198 2456.234525 2296.821379 2749.173261 2454.641033 1836.496732 2679.276349 2588.633889 1.037835751 1.076852285 0.824790329 0.948853577 0.887271618 1.062017025 0.948238004 0.709446299 1.035015558 1 11.33797522 -6.770685621 24.9999492 1.022790009 0.908555941 0.370864628 0.088136943 186.7315657 504883.4666 0.01378698 0.01825982 1.70E-07 6.770685621 -0.114234068 NQS(ph)SEDILR ddPTM_HeLa_Curcumin_4h_R1 4 NQSSEDILR 9 0 Q13625-2;Q13625;Q13625-3;H0Y847 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 0 NQS(0.944)S(0.056)EDILR;NQS(0.805)S(0.195)EDILR;NQS(0.859)S(0.141)EDILR;NQS(0.72)S(0.28)EDILR ;;; 136.7 0.0028663 67233000 7722.3 8943 7651.1 7327.4 9097.1 14085 11616.9 9000.5 11401.2 10086.6 TRUE FALSE FALSE 7111.071806 9715.993071 7934.656497 7297.08116 8988.623024 11163.61223 11942.83895 11744.71102 10150.51688 10437.1086 0.681325842 0.930908496 0.760235119 0.699147766 0.861217735 1.069607748 1.144267 1.125283972 0.972541081 1 13.34943448 -5.213471947 3.403692318 0.833887318 1.128677495 0.598957059 0.10184232 0.156589743 3.684095788 0.018553043 0.050403659 6.12E-06 5.213471947 0.294790176 NQSFCPTVNLDK ddPTM_HeLa_Curcumin_4h_R1 1 NQSFCPTVNLDK 12 0 E9PLL6;P46776;E9PJD9 E9PLL6 RPL27A 60S ribosomal protein L27a 0 0 185.3 2.22E-44 0 2074.6 1440 1716 1498.2 1679.3 2152.6 1334.9 1186.3 1656.1 1419.9 FALSE FALSE TRUE 1910.393221 1564.467183 1779.59647 1492.000845 1659.275444 1706.126495 1372.353701 1547.997409 1474.429973 1469.241419 1.300258212 1.064812878 1.21123489 1.015490597 1.129341593 1.161229511 0.934055958 1.053603165 1.003531451 1 10.52085576 -6.251722289 24.87538746 1.143127364 1.061432753 0.039532771 0.104116377 1307.876765 3348112.958 0.019039584 0.031320606 5.60E-07 6.251722289 -0.081694611 NQSPT(ph)EAEKPASSSLPSSPPPQLLTR ddPTM_HeLa_Curcumin_4h_R1 2 NQSPTEAEKPASSSLPSSPPPQLLTR 26 1 Q99567;I3L2W3 Q99567 NUP88 Nuclear pore complex protein Nup88 1 0 NQS(0.156)PT(0.838)EAEKPAS(0.005)S(0.001)SLPSSPPPQLLTR;NQS(0.002)PT(0.887)EAEKPAS(0.077)S(0.02)S(0.008)LPS(0.003)S(0.003)PPPQLLTR ; 88.045 2.94E-05 58664000 3298.8 2232.53 3153.5 2394.74 2711.8 3600.6 3148.8 4529 3122.3 2922.1 TRUE FALSE FALSE 3037.696499 2425.499945 3270.371484 2384.8312 2679.463556 2853.794973 3237.146853 5909.871251 2779.791502 3023.642757 1.00464795 0.802178081 1.081599827 0.788727833 0.886170679 0.943826768 1.070611548 1.954553406 0.91935183 1 11.56207198 -4.259034454 3.644590273 0.967555365 2.067036624 0.916324162 0.0918772 0.05603219 1.347391851 0.012678308 0.167291726 5.51E-05 4.259034454 1.099481259 NQSPTEAEKPASS(ph)SLPSSPPPQLLTR ddPTM_HeLa_Curcumin_4h_R1 1 NQSPTEAEKPASSSLPSSPPPQLLTR 26 1 Q99567;I3L2W3 Q99567 NUP88 Nuclear pore complex protein Nup88 1 0 NQSPTEAEKPAS(0.024)S(0.284)S(0.148)LPS(0.271)S(0.271)PPPQLLT(0.002)R 87.808 1.66E-05 36323000 2012.1 1946.2 1942.4 1727.4 1923.4 2171.5 1777.1 1822.5 1918 1815.3 TRUE FALSE FALSE 1852.840162 2114.420856 2014.387053 1720.252477 1900.464711 1721.106422 1826.960643 2378.17186 1707.600199 1878.38154 0.986402455 1.125661007 1.072405691 0.915816324 1.011756489 0.916270942 0.972624892 1.266074975 0.90908059 1 10.87527442 -4.258222251 24.90594605 0.99734601 1.266075079 0.607225884 0.066374196 140.4540004 1087292.807 0.008271993 0.078967883 5.52E-05 4.258222251 0.268729069 NQSPTEAEKPASSSLPS(ph)SPPPQLLTR ddPTM_HeLa_Curcumin_4h_R1 1 NQSPTEAEKPASSSLPSSPPPQLLTR 26 1 Q99567;I3L2W3 Q99567 NUP88 Nuclear pore complex protein Nup88 1 0 NQS(0.001)PT(0.006)EAEKPAS(0.003)S(0.013)S(0.173)LPS(0.456)S(0.346)PPPQLLT(0.003)R 74.364 0.00015203 59329000 2137.8 1788.8 1957.3 1992.3 2102.3 2629.2 2248 2055.2 2080.9 1971.6 TRUE FALSE FALSE 1968.590874 1943.415901 2029.83926 1984.05639 2077.231446 2083.874283 2311.07283 2681.821019 1852.630476 2040.112953 0.964942098 0.952602109 0.994964155 0.972522814 1.018194332 1.021450444 1.132816115 1.314545361 0.908101913 1 10.99443332 -4.091091095 1.083207192 0.981125488 1.58327977 0.935961775 0.027976731 0.263990779 0.193336079 0.002766057 0.197911606 8.11E-05 4.091091095 0.602154282 NQTAEK(ac)EEFEHQQK ddPTM_HeLa_Curcumin_4h_R1 2 NQTAEKEEFEHQQK 14 1 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65;E9PM13 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 1 ; NQTAEK(1)EEFEHQQK;NQTAEK(1)EEFEHQQK 219.41 4.83E-27 11947000 2818.9 3759.9 3229.1 2934.7 8214.5 7538.6 6084.1 5403.3 5095.1 2741 FALSE TRUE FALSE 2595.781091 4084.889002 3348.773287 2922.556989 8116.547453 5975.009382 6254.803471 7050.741296 4536.180277 2836.249546 0.915216044 1.440243158 1.180704741 1.03043013 2.861718379 2.106658559 2.205307879 2.485938272 1.599358661 1 11.46976876 -5.774661016 24.99327384 1.021853419 2.377916783 0.791242091 0.299136554 51.70977777 97748.61862 0.0353858 0.064415468 1.68E-06 5.774661016 1.356063364 NQTAEKEEFEHQQK ddPTM_HeLa_Curcumin_4h_R1 2 NQTAEKEEFEHQQK 14 1 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65;E9PM13 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 ; ; 79.886 0.0044478 16787300 9369.2 7945.3 9932.3 9811.7 13546.4 12247.8 10085.9 8993.6 7940.9 7158.8 FALSE FALSE TRUE 8627.617934 8632.056328 10300.39978 9771.101785 13384.86803 9707.468219 10368.88321 11735.70724 7069.803137 7407.567767 1.164703207 1.165302377 1.390523867 1.319070185 1.806918067 1.31047984 1.39976893 1.58428618 0.954402762 1 12.8547842 -6.873873895 0.797357268 1.050511641 1.505836771 0.674240369 0.139966349 0.254163521 0.3254637 0.030032515 0.045621314 1.34E-07 6.873873895 0.45532513 NQTYSFSPS(ph)K ddPTM_HeLa_Curcumin_4h_R1 2 NQTYSFSPSK 10 0 Q86YS7;H0YFE9;Q86YS7-3 Q86YS7;Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 0 NQT(0.001)YS(0.133)FS(0.26)PS(0.606)K;NQT(0.003)YS(0.355)FS(0.173)PS(0.469)K ; 112.84 0.0063818 62804000 9438.3 7094.1 8356.1 8168.4 9171.1 8286.3 6137 4820.2 8484.4 7787.9 TRUE FALSE FALSE 8691.248596 7707.282393 8665.784417 8134.601325 9061.740622 6567.627974 6309.187703 6289.856791 7553.682547 8058.528945 1.078515527 0.956413068 1.075355623 1.009439983 1.124490671 0.814990927 0.782920524 0.78052171 0.937352536 1 12.97630079 -5.181565535 6.2065072 1.037394943 0.787871302 0.791027128 0.054745169 0.061606329 3.872853763 0.006450362 0.0166743 6.58E-06 5.181565535 -0.249523641 NQVALNPQNTVFDAK ddPTM_HeLa_Curcumin_4h_R1 2 NQVALNPQNTVFDAK 15 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 0 ; ; 246.25 2.13E-48 6820200 3909.2 3170.3 3850 3304.6 3709.1 4823.5 4114.4 3581.4 3544.1 3256.6 FALSE FALSE TRUE 3599.782695 3444.326605 3992.684387 3290.926441 3664.871405 3823.051728 4229.838991 4673.352373 3155.321097 3369.766608 1.068258759 1.022126161 1.184854873 0.976603671 1.087574254 1.134515286 1.255232033 1.386847493 0.93636191 1 11.71843296 -1 0.496278521 1.032351891 12.65710205 0.777482305 0.062174865 27.39900771 0.265597665 0.010592947 333.5429421 0.1 1 11.62475015 NQVALNPQNTVFDAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 NQVALNPQNTVFDAKR 16 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 1 NQVALNPQNTVFDAK(1)R 206.45 7.61E-19 1096900 478.69 333.13 216.54 215.78 417.05 948.2 536.92 644.2 933.27 329.23 FALSE TRUE FALSE 440.8011814 361.9242728 224.5651629 214.8871595 412.0769511 751.5326316 551.9845302 840.6136145 830.8926159 340.670718 1.293921544 1.062387384 0.659185398 0.630776724 1.209604845 2.206038241 1.620287571 2.467525297 2.438990415 1 8.412234137 -5.327920497 5.176361762 1.059940646 2.049948256 0.3788471 0.519490719 0.08831612 4.652399953 0.042876712 0.098752478 4.70E-06 5.327920497 0.990007611 NQVAMNPTNTVFDAK ddPTM_HeLa_Curcumin_4h_R1 4 NQVAMNPTNTVFDAK 15 0 P11142;E9PKE3;E9PNE6;P11142-2;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 ;;; ;;; 315.41 5.39E-154 21572400 6882.3 6332.53 6636.24 6230.26 7075.32 8186.17 6137.83 6009.23 6050.1 6158.59 FALSE FALSE TRUE 6337.558693 6879.885676 6882.184892 6204.480835 6990.95143 6488.266065 6310.040991 7841.416564 5386.419167 6372.600544 0.994501169 1.0796041 1.079964897 0.973618351 1.097032739 1.018150443 0.990183042 1.230489266 0.845246635 1 12.63766652 -4.257506198 24.87276057 1.014417537 1.230489356 0.484131037 0.06845448 162.8644756 1029880.935 0.006103318 0.06204243 5.53E-05 4.257506198 0.216071818 NQVAMNPTNTVFDAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 NQVAMNPTNTVFDAKR 16 1 P11142;E9PKE3;E9PNE6;P11142-2;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 1 ; NQVAMNPTNTVFDAK(1)R;NQVAMNPTNTVFDAK(1)R 209.39 4.60E-19 4127100 668.23 798 392.35 646.02 883.58 1674.92 965.4 1116.84 2375.56 963.5 FALSE TRUE FALSE 615.3388904 866.9755642 406.8908361 643.3469404 873.0438856 1327.522712 992.4865258 1457.359375 2114.967011 996.9815533 0.617201881 0.869600407 0.408122733 0.645294728 0.8756871 1.3315419 0.995491363 1.461771655 2.121370254 1 9.961423001 -5.375618737 4.548833403 0.7737591 1.234667876 0.024033384 0.466010815 0.148912383 4.925177221 0.031233211 0.072056945 4.21E-06 5.375618737 0.460908776 NQWIDNVEK ddPTM_HeLa_Curcumin_4h_R1 1 NQWIDNVEK 9 0 P18206;P18206-2 P18206 VCL Vinculin 0 0 94.309 0.015889 6017800 595.79 480.09 662.09 692.06 964.33 766.99 637.29 848.22 735.63 957.3 FALSE FALSE TRUE 548.6325928 521.5868404 686.6276378 689.1964391 952.8309946 607.9076282 655.1706422 1106.838373 654.9332295 990.5661037 0.553857628 0.526554299 0.693166902 0.695760168 0.961905511 0.613697184 0.661410319 1.117379617 0.661170645 1 9.952109444 -4.25266999 23.88095069 0.748633408 1.117379977 0.366270578 0.153383314 703.1057448 1914628.121 0.027328769 0.419739262 5.59E-05 4.25266999 0.368746569 NQYDNDVTVWS(ph)PQGR ddPTM_HeLa_Curcumin_4h_R1 1 NQYDNDVTVWSPQGR 15 0 P25786;P25786-2;B4DEV8 P25786 PSMA1 Proteasome subunit alpha type-1;Proteasome subunit alpha type 1 0 NQYDNDVTVWS(1)PQGR 207.85 1.11E-09 17998000 2380.1 2220.7 2318.8 2392.7 2743.6 4076.3 3363.5 2081.8 2665.5 2295.5 TRUE FALSE FALSE 2191.712574 2412.647413 2404.736768 2382.799641 2710.884362 3230.829431 3457.870758 2716.531237 2373.101319 2375.268454 0.922722048 1.01573673 1.012406309 1.003170668 1.14129599 1.360195487 1.45578103 1.143673353 0.999087625 1 11.21387486 -5.539626824 2.393738941 0.972240072 1.333470176 0.776959616 0.078083759 0.088410613 1.011535673 0.011226381 0.026865842 2.89E-06 5.539626824 0.361230104 NRDLLGSGYTETY(ph)TAANGSEVTEQPR ddPTM_HeLa_Curcumin_4h_R1 1 NRDLLGSGYTETYTAANGSEVTEQPR 26 1 H0YMT6;P78325-3;P78325 H0YMT6 ADAM8 Disintegrin and metalloproteinase domain-containing protein 8 1 0 NRDLLGS(0.009)GY(0.009)T(0.009)ET(0.033)Y(0.765)T(0.174)AANGS(0.001)EVTEQPR 49.25 0.0059159 0 2598.7 1837 2328.8 2379.7 2560.8 3031.6 1954.4 2261.9 2830.2 2405.3 TRUE FALSE FALSE 2393.010153 1995.782094 2415.107377 2369.853432 2530.264133 2402.811987 2009.235204 2951.542897 2519.734141 2488.883996 0.961479184 0.801878311 0.97035755 0.952175126 1.01662598 0.965417428 0.807283589 1.185890103 1.012395172 1 11.28128327 -8.512194714 1.374154874 0.993275933 0.951587963 0.028842203 0.101729615 1.170558842 4.438229189 0.026958641 0.017712789 3.07E-09 8.512194714 -0.041687971 NREEEWDPEYT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 NREEEWDPEYTPK 13 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 NREEEWDPEYT(1)PK;NREEEWDPEYT(1)PK;NREEEWDPEY(0.002)T(0.998)PK ;; 125.61 0.0016291 67855000 13535.3 11508.5 11471.2 13307.2 13671.2 20827.4 21083 8544.5 16281.5 12131.3 TRUE FALSE FALSE 12463.96672 12503.24346 11896.33276 13252.13833 13508.17987 16507.56247 21674.53224 11149.67872 14495.46018 12552.86177 0.992918344 0.996047251 0.947698858 1.055706545 1.07610361 1.315043754 1.726660632 0.888218075 1.15475343 1 13.61572868 -5.331308383 3.208880308 0.998101425 1.355618352 0.286281913 0.196763372 0.170123298 3.423908812 0.02427388 0.060853365 4.66E-06 5.331308383 0.357516927 NREEEWDPEYTPK ddPTM_HeLa_Curcumin_4h_R1 2 NREEEWDPEYTPK 13 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 0 0 ; ; 128.21 0.0015279 28195000 7093 5758.6 6006.3 6378.3 5525.3 7168.3 5493.8 6246.8 6746 6360.7 FALSE FALSE TRUE 6531.581566 6256.347724 6228.898762 6351.908285 5459.414406 5681.513777 5647.941242 8151.420563 6005.980678 6581.733852 0.99238008 0.950562248 0.946391772 0.965081303 0.829479667 0.863224479 0.858123614 1.238491368 0.912522568 1 12.68425197 -7.157972336 1.731321904 0.997517238 0.936241145 0 0.110615552 0.803105197 4.598739856 0.018894546 0.023325275 6.95E-08 7.157972336 -0.061276092 NRENSS(ph)PCQGNGEQAGR ddPTM_HeLa_Curcumin_4h_R1 1 NRENSSPCQGNGEQAGR 17 1 Q5T5X7 Q5T5X7 BEND3 BEN domain-containing protein 3 1 0 NRENS(0.379)S(0.621)PCQGNGEQAGR 83.948 0.0033658 0 461.74 345.65 335.43 367.49 327.98 401.57 248.84 0 304.49 444 TRUE FALSE FALSE 425.1927918 375.5264458 347.8613309 365.9694238 324.0690527 318.2798554 255.8217807 0 271.0882088 459.428967 0.925481026 0.81737651 0.757160205 0.796574552 0.705373575 0.692772721 0.556825536 0 0.590054673 1 8.843698011 -4.6932946 0.563973622 0.954454967 4.39E-37 0.614503394 0.162781982 0.773508027 0.222507018 0.022653136 0.437870547 2.03E-05 4.6932946 -0.954454967 NREPVQLETLSIR ddPTM_HeLa_Curcumin_4h_R1 2 NREPVQLETLSIR 13 1 J3QLI9;P62314 J3QLI9 SNRPD1 Small nuclear ribonucleoprotein Sm D1 0 0 ; ; 122.52 0.00055577 9527600 4405.9 3667.2 3583.7 3596 3534 4981.9 4464.1 4062.6 4320.1 4294.8 FALSE FALSE TRUE 4057.168366 3984.176427 3716.515075 3581.120705 3491.859358 3948.597782 4589.350631 5301.268038 3846.195838 4444.04398 0.912945143 0.896520477 0.836291245 0.805824767 0.785739154 0.88851456 1.032696943 1.192892793 0.865472046 1 12.11765738 -4.433791407 2.804086246 0.918079357 1.199965795 0.644275986 0.069599961 0.209870844 2.701499257 0.012384927 0.110276818 3.68E-05 4.433791407 0.281886438 NRGPPPSWGR ddPTM_HeLa_Curcumin_4h_R1 1 NRGPPPSWGR 10 1 P84103;P84103-2 P84103 SRSF3 Serine/arginine-rich splicing factor 3 0 0 83.499 0.01641 1229000 715.36 518.34 735.82 760.68 464.4 773.02 587.94 427.8 797.41 564.8 FALSE FALSE TRUE 658.7385012 563.1429999 763.0901365 757.5325077 458.8623333 612.6869383 604.436014 558.2342507 709.936118 584.426758 1.127153218 0.963581821 1.305707047 1.296197509 0.785149426 1.048355384 1.034237406 0.955182567 1.214756355 1 9.190878423 -5.754209852 24.99999204 1.088635541 0.967954868 0.278110466 0.132486022 246.9413707 853925.3948 0.019452185 0.038271604 1.76E-06 5.754209852 -0.120680674 NRNEQESAVHPR ddPTM_HeLa_Curcumin_4h_R1 3 NRNEQESAVHPR 12 1 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 0 0 ;; ;; 100.04 0.004285 2918000 872.27 1084.38 891.34 773.89 999.33 1724.32 957.14 983.67 1004.837 1043.76 FALSE FALSE TRUE 803.2289091 1178.108975 924.3738445 770.6878482 987.4136424 1366.676595 983.9947724 1283.586455 894.6088951 1080.030582 0.743709412 1.090810755 0.855877472 0.713579653 0.914246002 1.265405459 0.911080472 1.188472323 0.828318114 1 10.07685645 -5.441613701 9.093850683 0.87887475 1.099666803 0.409713499 0.133863774 0.363025964 38.35594111 0.020369787 0.045585537 3.62E-06 5.441613701 0.220792053 NRPDYVS(ph)EEEEDDEDFETAVK ddPTM_HeLa_Curcumin_4h_R1 2 NRPDYVSEEEEDDEDFETAVK 21 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 NRPDY(0.038)VS(0.962)EEEEDDEDFETAVK;NRPDYVS(1)EEEEDDEDFETAVK ; 110.25 1.71E-05 92318000 10742.4 8786.2 8316.9 8935.5 8509.8 10810.5 7515.2 5071 9666 8264 TRUE FALSE FALSE 9892.127705 9545.639977 8625.13163 8898.527269 8408.326193 8568.280441 7726.056286 6617.124556 8605.663983 8551.173385 1.156815242 1.116295922 1.0086489 1.040620611 0.983295019 1.002000551 0.903508318 0.773826498 1.006372295 1 13.06190668 -3.588582975 0.608109227 1.074320356 0.247445362 0.751087624 0.050046024 2.918825977 0.413925955 0.011570743 2.038869672 0.00025788 3.588582975 -0.826874994 NRPDYVS(ph)EEEEDDEDFETAVKK ddPTM_HeLa_Curcumin_4h_R1 1 NRPDYVSEEEEDDEDFETAVKK 22 2 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 NRPDY(0.051)VS(0.949)EEEEDDEDFETAVKK 66.793 0.0021873 17027000 797.23 492.16 631.53 948.02 834.99 670.76 459.31 401.66 884.67 709.62 TRUE FALSE FALSE 734.1284043 534.7001174 654.9350574 944.0973444 825.0332896 531.636815 472.1970024 524.124285 787.6239143 734.2792422 0.999794577 0.72819724 0.891942765 1.285747016 1.123596096 0.72402539 0.643075516 0.713794228 1.072649027 1 9.520185006 -5.160873967 5.961202835 0.999550482 0.681496147 0.529961591 0.138219994 0.147463376 7.285790191 0.02002484 0.051984049 6.90E-06 5.160873967 -0.318054335 NRPEDYQGGR ddPTM_HeLa_Curcumin_4h_R1 5 NRPEDYQGGR 10 1 Q15084-3;Q15084;Q15084-4;Q15084-5;Q15084-2 Q15084-3 PDIA6 Protein disulfide-isomerase A6 0 0 ;;;; ;;;; 145.46 0.00097497 32989300 5520.48 4818.9 5214.6 5027.39 5494.46 5536.53 4432.55 3421.86 5737.91 5027.95 FALSE FALSE TRUE 5083.528183 5235.424243 5407.857663 5006.587992 5428.942153 4388.191268 4556.915423 4465.169362 5108.475629 5202.670888 0.977099704 1.006295489 1.039438738 0.962311109 1.043491366 0.843449713 0.875880009 0.858245593 0.981894826 1 12.34503673 -5.253306491 24.99560611 0.995200964 0.860860586 0.865638243 0.025606793 155.535586 478021.2953 0.003437583 0.008599143 5.58E-06 5.253306491 -0.134340378 SRSPGS(ph)PVGEGTGSPPK ddPTM_HeLa_Curcumin_4h_R1 1 SRSPGSPVGEGTGSPPK 17 1 E7EV99;E7ENY0;P35611-5;P35611-2;P35611-6;P35611-4;P35611;P35611-3;A0A0A0MSR2;H0Y9H2 E7EV99 ADD1 Alpha-adducin 1 0 S(0.237)RS(0.056)PGS(0.701)PVGEGTGS(0.005)PPK 157.62 0.001558 3676400 2708.2 1727.1 2510.7 2077.2 2505.5 3158.8 2619.4 4026.2 3061.2 2315.3 TRUE FALSE FALSE 2493.843112 1876.382828 2603.748751 2068.605097 2475.623549 2503.629273 2692.893314 5253.769846 2725.394019 2395.756503 1.040941811 0.783210992 1.08681694 0.863445469 1.03333688 1.0450266 1.124026299 2.192948173 1.137592245 1 11.22626557 -4.246810597 3.281376139 0.99992955 2.379617335 0.928671298 0.098655723 0.054212916 0.907291699 0.011633732 0.192106419 5.66E-05 4.246810597 1.379687785 up NRS(ph)AEEGELAESK ddPTM_HeLa_Curcumin_4h_R1 1 NRSAEEGELAESK 13 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 NRS(0.998)AEEGELAES(0.002)K 196.97 2.80E-05 151350000 7046.6 6247.1 6143.9 6314.7 5980.2 7224 6052.7 6356.3 7008.4 6974.8 TRUE FALSE FALSE 6488.854174 6787.071487 6371.598339 6288.571445 5908.890021 5725.660969 6222.522472 8294.306609 6239.596054 7217.173781 0.899085206 0.940405717 0.882838426 0.871334353 0.818726305 0.793338382 0.862182713 1.149245794 0.864548401 1 12.81721828 -9.024966002 0.590152432 1.009887362 0.890611387 0 0.101131237 1.523298868 0.868975181 0.095416091 0.021965982 9.44E-10 9.024966002 -0.119275975 NRT(ph)PAAVR ddPTM_HeLa_Curcumin_4h_R1 1 NRTPAAVR 8 1 Q92688-2;Q92688 Q92688-2 ANP32B Acidic leucine-rich nuclear phosphoprotein 32 family member B 1 0 NRT(1)PAAVR 91.636 0.016333 9439500 790.02 632.48 603.2 552.48 757.05 750.3 456.78 635.05 709.66 679.21 TRUE FALSE FALSE 727.4890834 687.1487529 625.5551226 550.1939841 748.0226732 594.6793224 469.5960174 828.6738216 631.8120735 702.8124969 1.035111195 0.97771277 0.890073989 0.782846046 1.064327508 0.846142214 0.668166857 1.179082366 0.89897672 1 9.456996034 -6.885939394 3.733345102 1.01622692 0.893355149 0.037440431 0.138028841 0.305052461 8.149299111 0.02004297 0.026771842 1.30E-07 6.885939394 -0.122871771 NRVPS(ph)AGDVEK ddPTM_HeLa_Curcumin_4h_R1 2 NRVPSAGDVEK 11 1 Q15785 Q15785 TOMM34 Mitochondrial import receptor subunit TOM34 1 0 NRVPS(1)AGDVEK;NRVPS(1)AGDVEK ; 69.331 0.017888 134653000 9332.5 8113.9 8426.5 9406.8 8717.1 11296.4 8125.2 6972.9 10811.7 10198.2 TRUE FALSE FALSE 8593.822777 8815.229361 8738.793503 9367.877154 8613.154276 8953.399303 8353.171244 9098.905111 9625.68356 10552.58669 0.814380685 0.835361947 0.828118618 0.887732783 0.816212605 0.848455413 0.791575704 0.862244052 0.912163419 1 13.36530906 -9.272003127 0.803668981 1.009955217 0.83368697 0.598469231 0.036692861 0.199193005 0.210358869 0.022708592 0.00497769 5.35E-10 9.272003127 -0.176268247 NS(ph)DADFQNNEK ddPTM_HeLa_Curcumin_4h_R1 2 NSDADFQNNEK 11 0 E5RIM1;A0A087WTZ8;E5RFJ1;E5RHW9;Q96MF7 E5RIM1 NSMCE2 E3 SUMO-protein ligase NSE2 1 0 NS(1)DADFQNNEK;NS(1)DADFQNNEK ; 155.37 0.00043591 14817800 6206.5 5567.3 5747.1 5700.3 6992.3 11883.7 11629.4 3451.7 6793.6 7287.3 TRUE FALSE FALSE 5715.248976 6048.512605 5960.092582 5676.713669 6908.921389 9418.886663 11955.68967 4504.10744 6048.359077 7540.533133 0.757936989 0.802133284 0.79040732 0.752826567 0.916237787 1.249100892 1.585523126 0.597319495 0.802112924 1 12.88045081 -5.345257003 5.159917385 0.859368605 1.187078996 0.257713177 0.237558637 0.208814904 9.465795823 0.032502903 0.074500446 4.52E-06 5.345257003 0.327710391 NS(ph)FTPLSSSNTIR ddPTM_HeLa_Curcumin_4h_R1 1 NSFTPLSSSNTIR 13 0 O60825 O60825 PFKFB2 "6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase" 1 0 NS(0.79)FT(0.206)PLS(0.002)S(0.001)S(0.001)NTIR 99.069 0.0075191 8787200 1334.3 993.45 990.46 1294.5 1042.5 1385.8 1254.1 1171.3 1370.6 1288.9 TRUE FALSE FALSE 1228.688747 1079.319391 1027.167319 1289.143702 1030.068868 1098.369459 1289.286671 1528.423978 1220.248609 1333.689179 0.921270688 0.809273561 0.770169943 0.966599806 0.772345524 0.8235573 0.966707004 1.146012131 0.914942273 1 10.38120677 -8.319935546 1.14183962 0.985984795 0.889033647 0.028974486 0.110823574 0.67469299 1.804047354 0.032309835 0.022271359 4.79E-09 8.319935546 -0.096951149 NS(ph)GIWESPELDR ddPTM_HeLa_Curcumin_4h_R1 2 NSGIWESPELDR 12 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 0 NS(1)GIWESPELDR;NS(1)GIWESPELDR ; 121.95 0.0033655 9046000 3556.6 3914.5 4437 5020.7 4745.8 5702.5 4824.4 4185.3 5401.7 4769 TRUE FALSE FALSE 3275.091357 4252.851937 4601.439123 4999.925674 4689.209435 4519.73722 4959.75968 5461.378703 4809.147024 4934.722395 0.663682999 0.861821922 0.932461597 1.01321316 0.950247868 0.915905062 1.005073697 1.106724607 0.974552698 1 12.26875321 -6.636271827 3.06131775 0.8379949 0.990412484 0.224755563 0.098572423 0.297306391 5.600770725 0.021475591 0.031191305 2.31E-07 6.636271827 0.152417584 TSS(ph)PLFNK ddPTM_HeLa_Curcumin_4h_R1 2 TSSPLFNK 8 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 T(0.041)S(0.004)S(0.954)PLFNK;T(0.039)S(0.005)S(0.956)PLFNK ; 161.27 0.00082095 312800000 17355.1 13700.1 14524.1 15464.3 13278.7 14039.2 10474.4 3148.1 16754.9 13595.5 TRUE FALSE FALSE 15981.42552 14884.2756 15062.37592 15400.31282 13120.36018 11127.31167 10768.28347 4107.941198 14916.92939 14067.94261 1.136017253 1.058027887 1.070687899 1.094709671 0.932642429 0.790969367 0.765448351 0.292007247 1.060349036 1 13.78012373 -4.309159628 0.878129181 1.067222108 1.41E-16 0.929956759 0.06374402 0.42018126 0.249388171 0.011328974 0.423273917 4.91E-05 4.309159628 -1.067222108 down NS(ph)GVNYLILDDDDR ddPTM_HeLa_Curcumin_4h_R1 1 NSGVNYLILDDDDR 14 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 0 NS(1)GVNYLILDDDDR 123.59 0.0014904 21751000 642.21 355.21 474.65 494.41 543.87 601.7 331.25 252.96 429.75 367.75 TRUE FALSE FALSE 591.3784008 385.9127696 492.2409465 492.3642624 537.3847055 476.9006374 340.5439835 330.0863395 382.6075002 380.5292851 1.554094321 1.014147359 1.293569157 1.293893221 1.412203282 1.253256073 0.894921881 0.867440043 1.00546138 1 8.571863676 -4.75791185 6.092709817 1.26452841 0.8762373 0.372939154 0.175285137 0.123139466 17.48646023 0.02971851 0.103320418 1.75E-05 4.75791185 -0.38829111 NS(ph)LESISSIDR ddPTM_HeLa_Curcumin_4h_R1 2 NSLESISSIDR 11 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 NS(0.998)LES(0.002)ISSIDR;NS(0.992)LES(0.007)IS(0.001)SIDR ; 103.3 0.009186 14563200 2243.9 2290.11 2414.8 2496.3 2498.7 2598.18 1881 1057.36 2224.11 1845.52 TRUE FALSE FALSE 2066.292947 2488.056904 2504.294612 2485.970972 2468.904634 2059.28818 1933.775798 1379.744197 1980.130697 1909.651683 1.082026092 1.302885194 1.311388163 1.301792884 1.292855999 1.078358006 1.01263273 0.722510921 1.036906738 1 10.8990938 -4.271829298 2.149014341 1.116779657 0.62233034 0.510051595 0.126510711 0.558167359 2.902021408 0.022440757 0.524389251 5.35E-05 4.271829298 -0.494449317 KDGS(ph)SPPLLEK ddPTM_HeLa_Curcumin_4h_R1 1 KDGSSPPLLEK 11 1 Q6W2J9-4;Q6W2J9-2;Q6W2J9;H7BYY2;Q6W2J9-3 Q6W2J9-4 BCOR BCL-6 corepressor 1 0 KDGS(0.751)S(0.249)PPLLEK 67.846 0.020045 93336000 4073.2 3154.2 3807.6 3384.4 3217.7 3861.5 2522.3 731.37 3765.6 3611 TRUE FALSE FALSE 3750.801922 3426.834993 3948.713006 3370.39625 3179.331029 3060.581372 2593.06895 954.3613462 3352.523101 3736.481981 1.003832466 0.917128735 1.056799692 0.902023954 0.850888896 0.819107756 0.69398674 0.255417088 0.897240537 1 11.86746485 -4.307963784 0.910266212 0.991985693 2.39E-23 0.907960203 0.066198616 0.339603046 0.218990402 0.00882586 0.327744155 4.92E-05 4.307963784 -0.991985693 down NS(ph)PEDLGLSLTGDSCK ddPTM_HeLa_Curcumin_4h_R1 1 NSPEDLGLSLTGDSCK 16 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 NS(1)PEDLGLSLTGDSCK 145.48 0.000371 44236000 4443.7 3833 4035.7 3496.3 4328.9 4607 3257.4 2947.2 4278 3359.2 TRUE FALSE FALSE 4091.976456 4164.30744 4185.266592 3481.833237 4277.280695 3651.456268 3348.793877 3845.787713 3808.714103 3475.93195 1.177231463 1.198040554 1.204070348 1.001697757 1.230542127 1.050497053 0.963423314 1.106404777 1.095738972 1 11.76318412 -5.016128326 24.70659159 1.107001232 1.027925562 0.158063468 0.084195998 1028.738351 1575906.459 0.013756187 0.036244656 9.64E-06 5.016128326 -0.07907567 NS(ph)PGLLVSPGNLNK ddPTM_HeLa_Curcumin_4h_R1 1 NSPGLLVSPGNLNK 14 0 Q06413-5;A0A0D9SGI5;Q06413-6;A0A0D9SFD0;A0A0D9SGF3;A0A1B0GV32;A0A0R4J2G5;D8L7E9;D6RC63;Q06413-4;Q06413-3;Q06413-2;Q06413;D6RJG6;A0A0D9SFV9 Q06413-5 MEF2C Myocyte-specific enhancer factor 2C 1 0 NS(1)PGLLVSPGNLNK 187.56 2.15E-05 24378000 1658.8 1362.5 1270.6 1228.3 1501.6 1441.2 1414.8 759.83 1519.5 969.97 TRUE FALSE FALSE 1527.50423 1480.268429 1317.689554 1223.21762 1483.694401 1142.278874 1454.49548 991.4986692 1352.814652 1003.676385 1.521909105 1.474846325 1.312862964 1.218737073 1.478259748 1.138094799 1.449167781 0.98786689 1.347859401 1 9.971078462 -9.524769701 1.30449351 1.001501618 1.350255828 0 0.193805982 0.361136119 1.107818457 0.109987751 0.026844618 2.99E-10 9.524769701 0.34875421 NS(ph)PGSQVASNPR ddPTM_HeLa_Curcumin_4h_R1 2 NSPGSQVASNPR 12 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 1 0 NS(0.997)PGS(0.003)QVASNPR;NS(0.971)PGS(0.029)QVASNPR ; 192.4 4.57E-06 280878000 6366 5641.4 6232.3 5882.2 6838.8 7463.9 7571.7 3468.33 6199.8 4866.8 TRUE FALSE FALSE 5862.124383 6129.017478 6463.27452 5857.861015 6757.251777 5915.803005 7784.141524 4525.807851 5519.697451 5035.920938 1.164062037 1.217059909 1.28343447 1.163215445 1.341810537 1.174721184 1.545723537 0.898705104 1.096065153 1 12.29803992 -8.296054591 0.543142464 0.998537587 1.254802389 0.163067513 0.155905753 0.760407719 0.492544494 0.0864199 0.041086035 5.06E-09 8.296054591 0.256264802 NS(ph)PGVPTGAK ddPTM_HeLa_Curcumin_4h_R1 1 NSPGVPTGAK 10 0 Q08379;R4GND7;B7ZC06 Q08379;B7ZC06 GOLGA2 Golgin subfamily A member 2 1 0 NS(1)PGVPTGAK 106.54 0.009095 46874000 8576.6 7571.1 7605.1 7957.9 7819.9 10461 7469.4 1725.4 8637.6 6214.1 TRUE FALSE FALSE 7897.75306 8225.512148 7886.951696 7924.972318 7726.6528 8291.27068 7678.971261 2251.466517 7690.07689 6430.039512 1.228258869 1.279231975 1.226579041 1.232492009 1.20164935 1.289458745 1.194233915 0.350148162 1.195961063 1 12.65061189 -4.259975342 24.97929747 1.160150104 0.350147894 0.895078197 0.086602866 40.80717033 696177.8463 0.016738626 0.141285484 5.50E-05 4.259975342 -0.81000221 NS(ph)PLDCGSASPNK ddPTM_HeLa_Curcumin_4h_R1 1 NSPLDCGSASPNK 13 0 H0YM23;O75179-6;O75179-7;O75179-2;O75179;O75179-4 H0YM23 ANKRD17 Ankyrin repeat domain-containing protein 17 1 0 NS(0.98)PLDCGS(0.02)ASPNK 141.82 0.00091348 7899100 2530.4 2540.8 2781.7 2762 2760.4 3262.5 2359.6 2474.5 2667.3 2420.8 TRUE FALSE FALSE 2330.11617 2760.41543 2884.792249 2750.571576 2727.484033 2585.820724 2425.804025 3228.963659 2374.703863 2504.92262 0.93021483 1.101996289 1.151649247 1.098066485 1.088849616 1.03229565 0.968414755 1.289047268 0.948014859 1 11.29055032 -7.252448607 24.34502666 0.967045892 1.097316687 0.407186192 0.079658598 351.6776676 952265.5613 0.012873927 0.015638729 5.59E-08 7.252448607 0.130270795 NS(ph)PQSS(ph)PTSTPK ddPTM_HeLa_Curcumin_4h_R1 3 NSPQSSPTSTPK 12 0 Q9Y6Y0 Q9Y6Y0 IVNS1ABP Influenza virus NS1A-binding protein 2 0 NS(0.991)PQS(0.026)S(0.538)PT(0.252)S(0.174)T(0.019)PK;NS(1)PQS(0.007)S(0.928)PT(0.062)S(0.002)TPK;NS(0.999)PQS(0.001)S(0.649)PT(0.102)S(0.225)T(0.023)PK ;; 124.81 0.0073357 98977000 23842.7 19142.9 22270.3 23502.3 24739.4 13696 11436.7 10826.4 17901.3 17282.3 TRUE FALSE FALSE 21955.52514 20797.52698 23095.65691 23405.05371 24444.39881 10855.29521 11757.58302 14127.31952 15937.57218 17882.85864 1.227741357 1.162986712 1.291496923 1.308798229 1.366917857 0.607022369 0.657477826 0.789992238 0.89122061 1 14.12628975 -5.251469592 24.99906274 1.158715875 0.682095479 0.714949497 0.142448085 296.5405645 743568.2748 0.020539383 0.05168578 5.60E-06 5.251469592 -0.476620396 NS(ph)QEDSEDS(ph)EDKDVK ddPTM_HeLa_Curcumin_4h_R1 1 NSQEDSEDSEDKDVK 15 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 2 0 NS(0.953)QEDS(0.047)EDS(1)EDKDVK 134.08 0.0025811 1684800000 8366 17870 8151.2 10176 8387.4 7962.1 8098.4 8480.8 9262.5 9993.2 TRUE FALSE FALSE 7703.822272 19414.60317 8453.290643 10133.89441 8287.385733 6310.670709 8325.619308 11066.55688 8246.426924 10340.46296 0.745017153 1.877537133 0.817496342 0.980023279 0.801452098 0.610288991 0.805149571 1.070218705 0.797491075 1 13.33601316 -5.758004484 24.25825761 0.96105234 0.805483315 0.067360623 0.323118404 171.2190551 1209170.445 0.047917363 0.092780828 1.75E-06 5.758004484 -0.155569026 NS(ph)S(ph)S(ph)LTRHQRIHTGEK ddPTM_HeLa_Curcumin_4h_R1 1 NSSSLTRHQRIHTGEK 16 2 A0A0C4DFR4;Q6P280 A0A0C4DFR4 ZNF529 Zinc finger protein 529 3 0 NS(0.995)S(0.995)S(0.995)LT(0.014)RHQRIHTGEK 82.505 0.0045564 0 1908.8 1519.3 1808 1637 2019.5 2319.5 1630.8 1756.5 1916.9 1866.6 TRUE FALSE FALSE 1757.716466 1650.621522 1875.00607 1630.226528 1995.418781 1838.409554 1676.555859 2292.048764 1706.620866 1931.464211 0.910043508 0.854595965 0.970769254 0.844036622 1.033111962 0.951821703 0.868023259 1.186689741 0.883589173 1 10.91547923 -4.250209365 24.76374793 0.943369916 1.186689903 0.593693535 0.063397308 823.8801073 1816731.794 0.008612298 0.176371174 5.62E-05 4.250209365 0.243319987 SSDYQFPSS(ph)PFTDTLK ddPTM_HeLa_Curcumin_4h_R1 4 SSDYQFPSSPFTDTLK 16 0 Q9UK61-3;Q9UK61 Q9UK61-3 FAM208A Protein FAM208A 1 0 SSDYQFPS(0.216)S(0.782)PFT(0.002)DTLK;SSDY(0.001)QFPS(0.217)S(0.782)PFT(0.001)DTLK;SSDYQFPS(0.082)S(0.918)PFT(0.001)DTLK;SSDYQFPS(0.202)S(0.659)PFT(0.136)DT(0.003)LK ;;; 179.66 1.69E-05 53367000 15170.3 13333.7 14645.9 14197.9 16626.4 13923.1 10519.1 1100.23 13354.9 10914.8 TRUE FALSE FALSE 13969.55475 14486.20561 15188.68994 14139.15285 16428.14104 11035.29211 10814.23764 1435.685062 11889.90088 11294.08849 1.236890853 1.2826361 1.344835394 1.251907391 1.454578743 0.977085679 0.957513096 0.127118276 1.052754359 1 13.46328022 -4.307869406 2.282355966 1.170369128 5.30E-19 0.827073566 0.146733541 0.193387179 1.259570485 0.023742525 0.432938775 4.92E-05 4.307869406 -1.170369128 down NS(ph)T(ph)Y(ph)SKPNS(ph)FLK ddPTM_HeLa_Curcumin_4h_R1 1 NSTYSKPNSFLK 12 1 Q9Y251-2 Q9Y251-2 4 0 NS(0.897)T(0.897)Y(0.871)S(0.335)KPNS(1)FLK 56.087 0.016069 7483900 5174.9 4732.8 4512.4 4752 5084.4 5269.1 4502.2 4614.6 4467.7 4060.4 TRUE FALSE FALSE 4765.301204 5141.882143 4679.633514 4732.337483 5023.771851 4176.229265 4628.519615 6021.570297 3977.604488 4201.498598 1.134190835 1.223820983 1.113801041 1.12634513 1.195709515 0.993985638 1.101635406 1.433195836 0.946710893 1 12.03668829 -13.52287875 0.143315497 0.418891257 1.21734066 0.351111632 0.106576669 73.61775625 0.729144916 12.04020369 0.281034052 3.00E-14 13.52287875 0.798449403 NS(ph)TELAPPLPVR ddPTM_HeLa_Curcumin_4h_R1 2 NSTELAPPLPVR 12 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 0 NS(0.914)T(0.086)ELAPPLPVR;NS(0.889)T(0.111)ELAPPLPVR ; 136.33 0.0016559 16187600 2816.5 2704.9 3032.7 2685.3 3794.4 2925 2702 1459.55 2714.8 2752.4 TRUE FALSE FALSE 2593.571053 2938.699503 3145.09453 2674.18894 3749.154258 2318.322028 2777.810848 1904.560076 2416.993232 2848.045695 0.910649382 1.03183018 1.104299181 0.938955771 1.316395402 0.814004506 0.975339284 0.668725252 0.848649738 1 11.47575658 -3.804004557 1.515665827 0.989736318 0.03345338 0.34380238 0.134640657 3.308764217 2.703362784 0.017736879 6.670692706 0.000157035 3.804004557 -0.956282937 NS(ph)TELAPPLPVRR ddPTM_HeLa_Curcumin_4h_R1 2 NSTELAPPLPVRR 13 1 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 0 NS(0.939)T(0.061)ELAPPLPVRR;NS(0.5)T(0.5)ELAPPLPVRR ; 82.837 0.0066477 5350700 3103.6 3022.9 2630.3 3567.4 3141 3135.3 2018.53 1290.4 3225.4 3121.4 TRUE FALSE FALSE 2857.946785 3284.186006 2727.781232 3552.639044 3103.545626 2485.003438 2075.164519 1683.83702 2871.58169 3229.868418 0.884849293 1.016817276 0.844548718 1.099933058 0.960889183 0.769382252 0.642491969 0.521333009 0.889070797 1 11.65725968 -4.880289819 1.890937813 0.95493241 0.54288905 0.81406139 0.072638721 0.112669692 0.752190319 0.010557565 0.053127695 1.32E-05 4.880289819 -0.41204336 NS(ph)WDSPAFSNDVIR ddPTM_HeLa_Curcumin_4h_R1 1 NSWDSPAFSNDVIR 14 0 A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90-2;Q6DN90;Q6DN90-3;A0A2R8Y695;A0A3B3IU98;A0A0C4DGT3 A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 0 NS(0.919)WDS(0.08)PAFSNDVIR 204.9 4.47E-09 18480000 2706.7 2482.4 1920.8 1968.2 2595.8 2465.1 1874.7 771.58 2252 2013.7 TRUE FALSE FALSE 2492.461839 2696.967595 1991.986538 1960.05611 2564.84678 1953.810473 1927.299037 1006.83119 2004.961234 2083.675925 1.196184977 1.2943316 0.95599633 0.940672245 1.230924036 0.937674832 0.924951435 0.483199512 0.962223161 1 11.0249152 -4.061185664 1.242975542 1.095320295 1.81E-17 0.667956778 0.123773615 0.975416446 0.916588091 0.018590426 1.532726742 8.69E-05 4.061185664 -1.095320295 NSAPASVS(ph)PDGTR ddPTM_HeLa_Curcumin_4h_R1 1 NSAPASVSPDGTR 13 0 A0A590UJM5;C9J637;A0A590UJ51;H0Y7H7;H0Y599;Q8N1I0-2;Q8N1I0;Q8N1I0-3 A0A590UJM5 DOCK4 Dedicator of cytokinesis protein 4 1 0 NSAPASVS(0.993)PDGT(0.007)R 211.49 1.08E-09 17586000 1965 2019.2 1844.8 1912.2 1910.8 2096.4 1183.8 958.27 2338.5 1960.7 TRUE FALSE FALSE 1809.468177 2193.730651 1913.169911 1904.287823 1888.014958 1661.583009 1217.014242 1250.442112 2081.972401 2028.834179 0.891875835 1.081276466 0.942989787 0.93861186 0.930591064 0.818984137 0.599858901 0.616335295 1.026191506 1 10.98643524 -4.942990695 2.070250499 0.956823067 0.592798296 0.878411598 0.053781718 0.085324531 0.70258337 0.008124128 0.034901772 1.14E-05 4.942990695 -0.364024771 NSAS(ph)ATTPLSGNSSR ddPTM_HeLa_Curcumin_4h_R1 1 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-4;Q9Y608;Q9Y608-2;Q9Y608-5 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 0 NS(0.012)AS(0.471)AT(0.471)T(0.046)PLSGNSSR 231.41 5.73E-21 39868000 4494.5 3657.2 4353 4299.9 4684.6 7016.6 5494.6 2990.9 4985.5 3017.7 TRUE FALSE FALSE 4138.755582 3973.312072 4514.326009 4282.108153 4628.739205 5561.278067 5648.763688 3902.811642 4438.603123 3122.56485 1.325434628 1.272451418 1.44571089 1.371343225 1.482351665 1.780996819 1.809014051 1.249873687 1.42146067 1 11.60851582 -7.649207844 0.259914972 0.902063638 1.695521768 0.210365555 0.20350111 0.892266864 0.21782198 0.280131067 0.224066448 2.24E-08 7.649207844 0.79345813 NSASAT(ph)TPLSGNSSR ddPTM_HeLa_Curcumin_4h_R1 1 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-4;Q9Y608;Q9Y608-2;Q9Y608-5 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 0 NSAS(0.006)AT(0.64)T(0.354)PLSGNSSR 239.33 1.69E-28 41635000 5469.8 4669.4 4439.3 4486.8 4643.2 7531.8 5231.9 3048.1 5078.2 3152.3 TRUE FALSE FALSE 5036.859558 5073.00213 4603.824363 4468.23481 4587.832873 5969.619779 5378.693033 3977.451658 4521.134165 3261.84219 1.544176347 1.555256764 1.411418485 1.369850088 1.40651589 1.830137521 1.648974021 1.219388133 1.386067719 1 11.67147127 -9.262862274 0.70371212 0.949152237 1.512679218 0.171132804 0.197788306 0.507739197 0.388781721 0.172772646 0.033896744 5.46E-10 9.262862274 0.563526981 NSASATTPLS(ph)GNS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-4;Q9Y608;Q9Y608-2;Q9Y608-5 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 2 0 NSASATT(0.002)PLS(0.996)GNS(0.902)S(0.1)R 130.64 0.0016962 30380000 3159 3397.1 3288.7 3690.7 3454.6 3697.9 4080 1602.1 2647.5 2986.7 TRUE FALSE FALSE 2908.961817 3690.730187 3410.582115 3675.428861 3413.406151 2930.913856 4194.473819 2090.572915 2357.075874 3090.487603 0.94126306 1.194222615 1.103574113 1.189271511 1.104487896 0.948366159 1.357220723 0.676454069 0.762687374 1 11.59361876 -7.284858957 24.49908102 0.972263107 1.093219689 0.137420258 0.18157278 967.2611146 1011843.627 0.025639399 0.029330318 5.19E-08 7.284858957 0.120956582 NSASATTPLS(ph)GNSSR ddPTM_HeLa_Curcumin_4h_R1 2 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-4;Q9Y608;Q9Y608-2;Q9Y608-5 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 0 NSASAT(0.009)T(0.029)PLS(0.958)GNS(0.004)SR;NSASAT(0.018)T(0.379)PLS(0.58)GNS(0.019)S(0.003)R ; 147.49 0.00046809 111203400 3261 2847.8 2553.1 3012.4 3430.9 4077.1 3548.1 1646.37 3373.4 2731.1 TRUE FALSE FALSE 3002.888409 3093.951142 2647.720132 2999.935487 3389.988758 3231.463502 3647.650137 2148.340634 3003.34646 2826.005522 1.062591133 1.094814259 0.936912583 1.061546223 1.19956905 1.143473881 1.290744165 0.760203976 1.062753217 1 11.46454857 -5.990652522 24.44597726 1.028588997 1.117331673 0.04506782 0.13453234 290.3692517 759379.4506 0.018066146 0.032713251 1.02E-06 5.990652522 0.088742675 NSASATTPLSGNS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 2 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-4;Q9Y608;Q9Y608-2;Q9Y608-5 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 0 NSASAT(0.007)T(0.126)PLS(0.102)GNS(0.502)S(0.264)R;NSASATTPLS(0.001)GNS(0.499)S(0.499)R ; 166.36 0.00022504 194080000 5055 4141 4422.9 4580.1 4745.8 5365 4831.2 4653.5 5172.7 4469 TRUE FALSE FALSE 4654.891416 4498.929588 4586.816565 4561.14876 4689.209435 4252.238524 4966.750469 6072.330728 4605.267751 4624.297417 1.006615924 0.972889324 0.991894801 0.986344162 1.014037163 0.919542612 1.074055153 1.313135852 0.995884853 1 12.17501847 -4.31227233 3.166028575 0.995272144 1.342994383 0.927862837 0.02735429 0.050662071 0.805778906 0.003536255 0.040375759 4.87E-05 4.31227233 0.347722239 NSASATTPLSGNSS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 NSASATTPLSGNSSR 15 0 C9JSU1;Q9Y608-4;Q9Y608;Q9Y608-2;Q9Y608-5 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 0 NSASATTPLS(0.023)GNS(0.232)S(0.745)R;NSASATTPLS(0.002)GNS(0.233)S(0.765)R ; 154.47 0.00038987 114938000 5957.8 5530.3 5123.5 6377.7 6130.9 6868.7 6079.9 6546.5 6268.9 5622.6 TRUE FALSE FALSE 5486.233843 6008.314489 5313.381417 6351.310767 6057.793022 5444.054194 6250.485631 8542.497714 5581.217354 5817.984931 0.942978352 1.032714 0.913268336 1.09166848 1.04121841 0.93572848 1.074338573 1.468291481 0.959304195 1 12.50630384 -4.273522097 3.002587454 0.983954377 1.540544327 0.881109753 0.052455799 0.083516936 1.113865662 0.007191108 0.109247119 5.33E-05 4.273522097 0.556589949 NSATCHSEDS(ph)DLEID ddPTM_HeLa_Curcumin_4h_R1 2 NSATCHSEDSDLEID 15 0 Q13371-2;Q13371 Q13371-2 PDCL Phosducin-like protein 1 0 NSATCHS(0.061)EDS(0.939)DLEID;NSAT(0.001)CHS(0.091)EDS(0.908)DLEID ; 94.487 0.0058513 135545000 6335.1 5804 4471.9 4394.9 7296 11342.7 5962.8 6611.3 8040.4 5659.8 TRUE FALSE FALSE 5833.67015 6305.671898 4637.632548 4376.715068 7208.999965 8990.096161 6130.10012 8627.054935 7158.388236 5856.477629 0.996105598 1.076700416 0.791880861 0.747328914 1.230944677 1.535068813 1.046721341 1.473079124 1.222302669 1 12.5158175 -5.570614611 8.770642428 0.972172435 1.331415003 0.501309361 0.173355978 0.156014715 26.54924092 0.021314222 0.04275052 2.69E-06 5.570614611 0.359242568 NSATFKS(ph)FEDR ddPTM_HeLa_Curcumin_4h_R1 1 NSATFKSFEDR 11 1 O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;O43399-6 O43399 TPD52L2 Tumor protein D54 1 0 NSATFKS(1)FEDR 141.85 0.011877 257520000 3595.4 2027.8 1833.7 2083.9 2176.7 8856.3 12740 5241.7 3292.7 1874.8 TRUE FALSE FALSE 3310.820296 2203.073996 1901.658535 2075.277374 2150.744274 7019.403549 13097.45011 6839.8702 2931.499048 1939.94916 1.706653125 1.135634913 0.980262047 1.069758639 1.108660123 3.618344074 6.751439872 3.525798686 1.511121584 1 10.92180313 -5.093782689 3.642073257 1.268059755 5.166737516 0.812498725 0.77114796 0.062185839 1.52081176 0.098849004 0.282601289 8.06E-06 5.093782689 3.898677761 VNLEESSGVENS(ph)PAGARPK ddPTM_HeLa_Curcumin_4h_R1 1 VNLEESSGVENSPAGARPK 19 1 Q8WVM8-2;Q8WVM8-3;Q8WVM8 Q8WVM8-2 SCFD1 Sec1 family domain-containing protein 1 1 0 VNLEESSGVENS(1)PAGARPK 106.74 0.000269 70543000 2080.4 1743.8 1716.2 2062.4 2051.7 3048.7 1679.3 623.44 2023.1 1970.7 TRUE FALSE FALSE 1915.734145 1894.526302 1779.803882 2053.866335 2027.234818 2416.365254 1726.416638 813.523986 1801.170992 2039.181678 0.939462219 0.929062046 0.872802998 1.00720125 0.994141346 1.184968107 0.846622278 0.3989463 0.883281274 1 10.9937746 -4.307590373 3.546459452 0.977295048 0.356959548 0.807851122 0.084154518 0.07118358 1.549213881 0.010830391 0.108102213 4.93E-05 4.307590373 -0.620335501 down NSDGGS(ph)DPETQKEK ddPTM_HeLa_Curcumin_4h_R1 1 NSDGGSDPETQKEK 14 1 O75554-2;O75554 O75554-2 WBP4 WW domain-binding protein 4 1 0 NS(0.023)DGGS(0.915)DPET(0.061)QKEK 68.033 0.015728 11466000 6485.7 10650 6433.5 5360 5295.5 5509.4 3449.5 3057.2 4095.3 5469.8 TRUE FALSE FALSE 5972.350001 11570.53854 6671.931169 5337.82174 5232.354621 4366.688336 3546.283686 3989.326206 3646.055836 5659.875143 1.05520879 2.044309857 1.17881243 0.94309885 0.924464673 0.771516725 0.62656571 0.7048435 0.644193687 1 12.46655451 -5.521541982 1.607903246 1.123397361 0.677416348 0.268817034 0.335429204 0.422919037 2.143769521 0.049841822 0.141617265 3.01E-06 5.521541982 -0.445981013 TDS(ph)DSDLQLYK ddPTM_HeLa_Curcumin_4h_R1 1 TDSDSDLQLYK 11 0 E9PIJ1;A0A590UK85;A0A590UJY6;A0A5F9UK94;H0Y360;Q01433-3;Q01433-5;Q01433-2;Q01433-4;Q01433 E9PIJ1 AMPD2 AMP deaminase 2 1 0 T(0.018)DS(0.981)DS(0.001)DLQLYK 115.37 0.0048017 5186500 483.66 731.57 788.5 700.69 642.3 892.43 919.28 2617.4 535.69 673.73 TRUE FALSE FALSE 445.3778006 794.803651 817.7225036 697.7907304 634.640992 707.3299582 945.0725227 3415.433211 476.9261472 697.1420674 0.638862323 1.140088496 1.172963937 1.00093046 0.910346717 1.014613794 1.355638351 4.899192533 0.68411615 1 9.445308876 -4.24666069 3.188091782 0.903704638 5.558713852 0.980078839 0.167961862 0.041161191 0.629369823 0.028276252 0.483057086 5.67E-05 4.24666069 4.655009214 up KPS(ph)EDEVLNK ddPTM_HeLa_Curcumin_4h_R1 1 KPSEDEVLNK 10 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 0 KPS(1)EDEVLNK 96.135 0.0070968 11790000 2334.8 2163.9 2320.9 2443.9 2885.1 3342.7 3960.4 8714.6 2874.3 3253.7 TRUE FALSE FALSE 2149.998116 2350.937874 2406.914596 2433.787789 2850.697067 2649.38634 4071.518165 11371.64142 2558.996481 3366.765833 0.638594492 0.69827781 0.71490407 0.722885971 0.846716763 0.786923259 1.20932621 3.377615785 0.760075576 1 11.71714767 -4.246255944 2.782816052 0.800571715 3.913007071 0.984235133 0.098433216 0.057096064 0.579847222 0.020444611 0.410417241 5.67E-05 4.246255944 3.112435356 up SVS(ph)VDESRPELIFR ddPTM_HeLa_Curcumin_4h_R1 2 SVSVDESRPELIFR 14 1 Q96BY7 Q96BY7 ATG2B Autophagy-related protein 2 homolog B 1 0 S(0.143)VS(0.857)VDESRPELIFR;S(0.016)VS(0.984)VDES(0.001)RPELIFR ; 88.108 0.0051155 15607700 3319.2 2902 3413.9 3478.6 3452.9 3797.7 4911.5 9314.2 2791.88 2942.3 TRUE FALSE FALSE 3056.481818 3152.835949 3540.422137 3464.206475 3411.726423 3010.014211 5049.303471 12154.0567 2485.617749 3044.544706 1.00392082 1.035568945 1.162874084 1.137840567 1.120603161 0.98865824 1.658475719 3.992076936 0.816416899 1 11.57201078 -4.246113377 2.400595492 1.032710058 4.754281012 0.988004941 0.09763717 0.034788839 0.232338869 0.011401415 0.271313431 5.67E-05 4.246113377 3.721570954 up NSEPEEVIPSR ddPTM_HeLa_Curcumin_4h_R1 2 NSEPEEVIPSR 11 0 P54577 P54577 YARS "Tyrosine--tRNA ligase, cytoplasmic;Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed" 0 0 ; ; 136.5 0.00035315 3926100 1752.85 1302.36 1376.86 1599.99 1666.21 1920.6 1363.96 1445.19 1502.33 1433.59 FALSE FALSE TRUE 1614.110073 1414.930195 1427.887643 1593.369665 1646.341534 1522.24591 1402.229047 1885.821778 1337.528158 1483.407146 1.088109948 0.953838061 0.962572984 1.074128347 1.109837942 1.026182134 0.945275915 1.271277264 0.901659508 1 10.53469891 -4.248216277 24.99891673 1.032134079 1.271277419 0.546012301 0.068949042 1199.619672 2267901.68 0.008228111 0.208378567 5.65E-05 4.248216277 0.23914334 DMS(ph)PLSETEMALGK ddPTM_HeLa_Curcumin_4h_R1 2 DMSPLSETEMALGK 14 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 DMS(0.999)PLS(0.001)ETEMALGK;DMS(0.907)PLS(0.088)ET(0.005)EMALGK ; 114.7 0.0026315 14375000 3699.1 3377.8 3750.6 3433.6 4227.8 4271.2 3821.7 5506.1 3193 2994 TRUE FALSE FALSE 3406.312332 3669.761981 3889.600535 3419.392673 4177.386246 3385.304974 3928.926616 7184.884543 2842.735888 3098.041277 1.099505148 1.184542636 1.255503135 1.10372728 1.348395929 1.092724296 1.268196988 2.31917005 0.917591353 1 11.59714065 -4.245947809 2.961781328 1.101024512 2.548812665 0.902325509 0.116872107 0.089455717 1.091382766 0.016655393 0.311552838 5.68E-05 4.245947809 1.447788153 up SVS(ph)DQFYR ddPTM_HeLa_Curcumin_4h_R1 1 SVSDQFYR 8 0 P55010;H0YK29;H0YK11;H0YMJ8;H0YM54;H0YLZ1;H0YN40 P55010 EIF5 Eukaryotic translation initiation factor 5 1 0 S(0.001)VS(0.999)DQFYR 104.43 0.012922 14664000 912.51 653.33 739.33 721.46 976.05 1470.6 1423.6 5288.3 800.62 865.14 TRUE FALSE FALSE 840.2838706 709.800934 766.7302202 718.4747897 964.4112412 1165.580983 1463.542385 6900.678326 712.7939891 895.2035506 0.938651182 0.792893341 0.856487019 0.802582596 1.077309446 1.302028999 1.634871068 7.708501961 0.796236776 1 9.806071948 -4.245741795 3.30831629 0.969147545 8.756284885 0.994112657 0.155132719 0.019354188 0.331548986 0.023594649 0.389601711 5.68E-05 4.245741795 7.787137339 up NSGAGSGGGGPGGAGGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 NSGAGSGGGGPGGAGGKR 18 1 Q66K64;K7ENG0 Q66K64 DCAF15 DDB1- and CUL4-associated factor 15 0 1 ; NSGAGSGGGGPGGAGGK(1)R;NSGAGSGGGGPGGAGGK(1)R 151.56 0.0009633 147610 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 NSGEPLPPKPGPGS(ph)PSHPGALDLDGVSR ddPTM_HeLa_Curcumin_4h_R1 1 NSGEPLPPKPGPGSPSHPGALDLDGVSR 28 1 A1X283;G3V144;A0A1B0GUF2 A1X283 SH3PXD2B SH3 and PX domain-containing protein 2B 1 0 NSGEPLPPKPGPGS(0.784)PS(0.214)HPGALDLDGVS(0.002)R 54.732 0.0017883 44911000 8512.6 5902 6820.7 6991.2 6645.6 8620.4 6174.8 5973.9 7753.6 6268.1 TRUE FALSE FALSE 7838.818728 6412.142581 7073.481142 6962.272267 6566.35556 6832.431868 6348.048269 7795.31461 6903.049479 6485.916008 1.208590848 0.988625596 1.090590925 1.073444716 1.012402188 1.053425894 0.978743521 1.201883373 1.064313733 1 12.66309463 NSGLSK(ac)EQK ddPTM_HeLa_Curcumin_4h_R1 2 NSGLSKEQK 9 1 O95251-4;O95251;O95251-2;E7EUP3;O95251-3;O95251-5 O95251-4 KAT7 Histone acetyltransferase KAT7;Histone acetyltransferase 0 1 ; NSGLSK(1)EQK;NSGLSK(1)EQK 166.66 1.27E-11 77180000 9374.5 7997 7767.5 8471.9 8190.3 9278.6 7386.8 5003.3 9819.4 7692.1 FALSE TRUE FALSE 8632.498433 8688.225046 8055.370383 8436.845523 8092.636022 7354.113769 7594.053727 6528.783138 8742.236387 7959.399902 1.084566492 1.091567851 1.012057502 1.059985128 1.016739468 0.923953295 0.954098779 0.820260725 1.098353707 1 12.95844395 -4.369052815 0.80009417 1.045012896 0.734295025 0.783944782 0.038624734 0.85040981 0.430482937 0.006847723 0.226122745 4.28E-05 4.369052815 -0.310717872 NSGNFQK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 NSGNFQKK 8 1 P46063 P46063 RECQL ATP-dependent DNA helicase Q1 0 1 ; NSGNFQK(1)K;NSGNFQK(1)K 102.61 0.0037178 2036970 349.67 294.75 459.59 314.21 388.26 619.27 280.14 210.29 256.798 428.4 FALSE TRUE FALSE 321.9932505 320.2268766 476.6228097 312.9098823 383.6302531 490.8264214 287.9999744 274.4064529 228.6279019 443.2868681 0.726376696 0.722391976 1.075201735 0.705885748 0.865422102 1.107243315 0.649692096 0.619026803 0.51575609 1 8.792096815 -9.485236161 1.228864305 0.999966887 0.808282805 0 0.217910218 0.680428919 1.839244492 0.109339953 0.026739772 3.27E-10 9.485236161 -0.191684082 Y(ph)LKRSIITS(ph)REQGIR ddPTM_HeLa_Curcumin_4h_R1 1 YLKRSIITSREQGIR 15 3 Q8NG66-4 Q8NG66-4 2 0 Y(0.942)LKRS(0.054)IIT(0.004)S(0.999)REQGIR 60.062 0.018348 44280000 6848.7 5899.3 6287.6 6093.7 6069.1 5175 4442.4 1478.4 7520.7 6102.4 TRUE FALSE FALSE 6306.618168 6409.209205 6520.623987 6068.485884 5996.729946 4101.646666 4567.041788 1929.157354 6695.698026 6314.457946 0.99875844 1.015005446 1.03264984 0.961046211 0.949682459 0.649564333 0.723267433 0.305514325 1.060375741 1 12.62444318 -4.306197633 0.76973611 1.005810007 5.08E-15 0.915282728 0.066411123 0.427504592 0.186682018 0.009450351 0.363697613 4.94E-05 4.306197633 -1.005810007 down SNS(ph)DVTISDIDAEDVLDQNAVNPNTGAALHR ddPTM_HeLa_Curcumin_4h_R1 1 SNSDVTISDIDAEDVLDQNAVNPNTGAALHR 31 0 Q9P2F8 Q9P2F8 SIPA1L2 Signal-induced proliferation-associated 1-like protein 2 1 0 S(0.127)NS(0.63)DVT(0.243)ISDIDAEDVLDQNAVNPNTGAALHR 152.74 1.21E-13 27720000 1153.1 912.4 1216.8 1155.7 1211.4 1368.7 808.11 253.55 1261.7 1389.4 TRUE FALSE FALSE 1061.830918 991.2637904 1261.895678 1150.91802 1196.954846 1084.816192 830.7833917 330.8562278 1123.294667 1437.681547 0.73857171 0.689487733 0.877729621 0.80053752 0.832559094 0.754559446 0.577863292 0.23013179 0.781323701 1 10.48952843 -4.305782699 1.256874693 0.853081304 7.77E-15 0.819282302 0.083753392 0.509964054 0.712220101 0.016907105 0.548366927 4.95E-05 4.305782699 -0.853081304 down NSGSFPS(ph)PSIS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 NSGSFPSPSISPR 13 0 Q9ULD2-2;Q9ULD2;Q9ULD2-4;Q9ULD2-7;Q9ULD2-3;Q9ULD2-6 Q9ULD2-2 MTUS1 Microtubule-associated tumor suppressor 1 2 0 NS(0.003)GS(0.081)FPS(0.761)PS(0.163)IS(0.992)PR 116.87 0.0066715 7170500 3714 3289.7 3242 3392.5 3426.2 3270.7 2512.4 1236.1 3877.4 3037.1 TRUE FALSE FALSE 3420.032981 3574.047009 3362.151372 3378.462734 3385.344803 2592.319952 2582.891182 1612.9812 3452.058921 3142.638999 1.088267848 1.137275713 1.069849694 1.075040033 1.077229934 0.82488633 0.821886059 0.513256916 1.098458627 1 11.61776084 -4.320126635 0.99289776 1.05749165 0.285781392 0.905555343 0.056955816 0.415475768 0.333626967 0.009550767 0.333252843 4.78E-05 4.320126635 -0.771710257 GSSDAVSPDTFTAEVSSDAVPDVRS(ph)PATPACR ddPTM_HeLa_Curcumin_4h_R1 1 GSSDAVSPDTFTAEVSSDAVPDVRSPATPACR 32 1 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 0 GSSDAVS(0.001)PDT(0.043)FT(0.039)AEVS(0.021)S(0.021)DAVPDVRS(0.588)PAT(0.288)PACR 49.087 0.0058241 8490000 1204.6 909.92 937.73 1151.1 909.38 1274 732.84 334.56 1353.4 912.92 TRUE FALSE FALSE 1109.254639 988.5694303 972.4830987 1146.337053 898.5362374 1009.758039 753.4015181 436.5658039 1204.935406 944.643902 1.17425692 1.046499563 1.029470573 1.213512362 0.951190428 1.068929823 0.797550819 0.462148544 1.275544577 1 9.883626776 -4.30563948 1.469798781 1.081174747 0.240449726 0.812057813 0.096186981 0.293873987 0.605491283 0.012061151 0.350504532 4.95E-05 4.30563948 -0.840725021 down ENPVVVAEK(ac)IQR ddPTM_HeLa_Curcumin_4h_R1 2 ENPVVVAEKIQR 12 1 O76080 O76080 ZFAND5 AN1-type zinc finger protein 5 0 1 ; ENPVVVAEK(1)IQR;ENPVVVAEK(1)IQR 136.93 0.00022968 6553800 1030.88 849.29 965 952.11 716.31 1441.56 1189.03 2357.3 1156.89 663.5 FALSE TRUE FALSE 949.2847602 922.6988432 1000.763749 948.1704211 707.7684711 1142.564206 1222.390982 3076.029918 1029.982061 686.5565756 1.382675214 1.343951651 1.457656637 1.38105213 1.030896063 1.664195271 1.780466498 4.480373545 1.5002144 1 9.4232348 -3.838217676 1.427387489 1.230066349 10.07360997 0.95228608 0.208416513 0.514247723 0.413131883 0.031662122 8.732071689 0.000145138 3.838217676 8.843543624 up NSKS(ph)PTEYHEPVYANPFYRPTTPQR ddPTM_HeLa_Curcumin_4h_R1 1 NSKSPTEYHEPVYANPFYRPTTPQR 25 2 S4R313;Q9NP74-2;Q9NP74;Q9NP74-3 S4R313 PALMD Palmdelphin 1 0 NS(0.215)KS(0.345)PT(0.345)EY(0.094)HEPVYANPFY(0.001)RPTTPQR 40.319 0.01607 59401000 1013.5 851.06 1052.9 1128.2 887.19 1046.9 845.02 1251.2 1077.5 1162.9 TRUE FALSE FALSE 933.2804056 924.6218342 1091.9214 1123.531807 876.6108387 829.761139 868.7289869 1632.68512 959.3009458 1203.310688 0.77559388 0.768398256 0.907430982 0.933700513 0.728499171 0.68956517 0.721949032 1.356827572 0.797218004 1 10.23279347 -9.461307761 1.208571083 0.999637835 0.839506262 0 0.194133296 0.909847672 2.385835911 0.119956063 0.029932365 3.46E-10 9.461307761 -0.160131572 NSLDCEIVSAK ddPTM_HeLa_Curcumin_4h_R1 2 NSLDCEIVSAK 11 0 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 0 0 ; ; 227.36 3.98E-40 17328400 8071.9 6220.6 6405.2 7372.5 6574.8 8571.5 6362.3 6562.3 7787.8 7216.4 FALSE FALSE TRUE 7433.000598 6758.280946 6642.582347 7341.994548 6496.399804 6793.674279 6540.809015 8563.115061 6933.497824 7467.169363 0.995424134 0.905065978 0.889571674 0.983236645 0.869994972 0.909805838 0.875942234 1.14676856 0.928530945 1 12.86634574 -7.283654105 20.35732596 0.997839228 0.933450372 0.009297443 0.079637501 106.3000109 97411.35199 0.012088696 0.013838293 5.20E-08 7.283654105 -0.064388856 NSLESYAFNMK ddPTM_HeLa_Curcumin_4h_R1 6 NSLESYAFNMK 11 0 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65;E9PM13 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 ;;;;; ;;;;; 172.61 4.66E-09 74844300 6435.43 5300.56 6288.45 6022.02 6348.07 7993.38 6264.53 5548.68 6569.27 5565.01 FALSE FALSE TRUE 5926.058925 5758.716788 6521.505489 5997.102477 6272.373411 6335.462884 6440.295852 7240.446989 5848.637517 5758.393683 1.029116669 1.00005611 1.132521645 1.041454059 1.089257483 1.100213572 1.118418817 1.257372696 1.015671703 1 12.49145071 -1 0.312147915 1.007691182 3.051101376 0.778830143 0.035558366 15.32354386 0.195782195 0.011764115 17.97139802 0.1 1 2.043410195 NSLLAGGDDDTMSVIS(ph)GISSR ddPTM_HeLa_Curcumin_4h_R1 2 NSLLAGGDDDTMSVISGISSR 21 0 Q8N3U4;Q8N3U4-2 Q8N3U4 STAG2 Cohesin subunit SA-2 1 0 NSLLAGGDDDT(0.075)MS(0.049)VIS(0.857)GIS(0.019)S(0.001)R;NSLLAGGDDDTMS(0.001)VIS(0.996)GIS(0.003)SR ; 153.58 3.00E-06 53285000 4780.1 4472 4822.4 4694.6 4754.9 7907.3 7583.3 7338.5 5730.9 5097.2 TRUE FALSE FALSE 4401.750041 4858.539753 5001.122386 4675.174989 4698.200923 6267.236846 7796.066989 9575.974868 5102.234608 5274.327321 0.834561409 0.921167659 0.94820099 0.886402133 0.890767796 1.1882533 1.478115884 1.815582213 0.967371628 1 12.36477139 -4.648753313 1.445135332 0.915883976 1.888378504 0.969358441 0.052654279 0.092686827 0.279144902 0.010099575 0.105343578 2.25E-05 4.648753313 0.972494528 NSLLAGGDDDTMSVISGIS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 2 NSLLAGGDDDTMSVISGISSR 21 0 Q8N3U4;Q8N3U4-2 Q8N3U4 STAG2 Cohesin subunit SA-2 1 0 NSLLAGGDDDT(0.19)MS(0.194)VIS(0.059)GIS(0.445)S(0.112)R;NSLLAGGDDDT(0.017)MS(0.023)VIS(0.01)GIS(0.771)S(0.179)R ; 79.695 0.0014094 38508000 6270.5 5625.4 4672.9 5094 4942.8 7294.9 7344.7 7286.2 7138.3 5407.6 TRUE FALSE FALSE 5774.183308 6111.63451 4846.081785 5072.922378 4883.860338 5781.85551 7550.772515 9507.728838 6355.246349 5595.513697 1.031930868 1.092238325 0.866065574 0.906605301 0.872817154 1.033302003 1.3494333 1.699169969 1.135775318 1 12.45005487 -4.501048528 2.15863408 0.991558188 1.734328173 0.877591596 0.084648563 0.09401475 0.686570449 0.01130868 0.110188267 3.15E-05 4.501048528 0.742769985 NSMES(ph)QQRIRMMK ddPTM_HeLa_Curcumin_4h_R1 1 NSMESQQRIRMMK 13 2 Q8TAT5 Q8TAT5 NEIL3 Endonuclease 8-like 3 1 0 NS(0.165)MES(0.835)QQRIRMMK 53.557 0.018463 81285000 810.4 912.29 841.13 1141.3 1341.4 1121.6 855.28 873.02 1345.3 1204.3 TRUE FALSE FALSE 746.2559849 991.1442825 872.3030177 1136.577603 1325.404681 888.967517 879.2768549 1139.199779 1197.723956 1246.149335 0.598849563 0.795365575 0.699998783 0.912071748 1.063600199 0.713371577 0.705595092 0.914175971 0.961139987 1 10.28326125 -6.231766471 24.7757748 0.796835217 0.856056128 0.024445642 0.144719517 2508.392188 2094415.422 0.027155351 0.045027764 5.86E-07 6.231766471 0.059220911 NSNILEDLETLR ddPTM_HeLa_Curcumin_4h_R1 3 NSNILEDLETLR 12 0 B0YIW6;P48444;Q6P1Q5 B0YIW6 ARCN1 Coatomer subunit delta 0 0 ;; ;; 180.24 3.45E-14 1714960 1321.79 1492.22 1424.35 1414.85 1340.38 2007.94 1520.57 1102.97 1621.97 1759.43 FALSE FALSE TRUE 1217.168927 1621.200848 1477.137664 1408.995726 1324.396844 1591.47061 1563.233102 1439.260476 1444.043949 1820.570062 0.668564727 0.890490776 0.811359966 0.773931064 0.727462717 0.874160596 0.85865034 0.790554841 0.7931823 1 10.83017455 -9.568366785 1.346607915 0.999972679 0.786381649 0 0.089787839 0.270147349 0.878238695 0.052186951 0.01225428 2.70E-10 9.568366785 -0.213591029 NSNLVGAAHEELQQSR ddPTM_HeLa_Curcumin_4h_R1 4 NSNLVGAAHEELQQSR 16 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ;;; ;;; 181.51 8.34E-08 51997000 8030.9 7184 6512.1 6776 8453.6 10363.6 7014.8 6256 9910.8 7417.7 FALSE FALSE TRUE 7395.245791 7804.952949 6753.444155 6747.962707 8352.796341 8214.072538 7211.616409 8163.425601 8823.610036 7675.464523 0.963491626 1.016870435 0.879874324 0.879160172 1.088246362 1.070172693 0.939567421 1.063574143 1.149586453 1 12.90603835 -4.24000267 22.99981748 0.981647459 1.063574394 0.016851821 0.084819104 3043.628183 3265408.648 0.009097622 0.488731497 5.75E-05 4.24000267 0.081926934 TDPASNTK(ac)LIAMK ddPTM_HeLa_Curcumin_4h_R1 4 TDPASNTKLIAMK 13 1 E7EWM1;Q15596 E7EWM1 NCOA2 Nuclear receptor coactivator 2 0 1 ;;; TDPASNTK(1)LIAMK;TDPASNTK(1)LIAMK;TDPASNTK(1)LIAMK;TDPASNTK(1)LIAMK 267.02 1.94E-77 22750700 5762.64 5056.01 5036.12 4768.05 4627.62 6047.7 4097.03 552.13 6108 4573.07 FALSE TRUE FALSE 5306.520963 5493.028975 5222.763037 4748.321072 4572.438654 4793.338848 4211.981635 720.4718953 5437.967681 4731.983842 1.121415698 1.160830036 1.103715315 1.003452512 0.966283657 1.012966022 0.890109048 0.152255781 1.149194051 1 12.20822943 -4.271343933 2.603692348 1.056101637 4.29E-19 0.946540013 0.064836773 0.082157139 0.723289984 0.010059251 0.186930961 5.35E-05 4.271343933 -1.056101637 down NSNPALNDNLEK ddPTM_HeLa_Curcumin_4h_R1 2 NSNPALNDNLEK 12 0 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 0 0 ; ; 299.29 4.47E-115 18270800 8827.3 7261 6956.7 8186 7612.2 9051.9 6711.2 7511.7 8839.7 7242.9 FALSE FALSE TRUE 8128.60989 7888.608486 7214.521422 8152.128501 7521.429487 7174.433904 6899.49821 9801.98275 7870.007026 7494.590236 1.084596974 1.052573688 0.962630537 1.087735052 1.00358115 0.957281676 0.920597123 1.307874406 1.050091703 1 12.87163389 -2.369159496 0.003727605 0.005558265 2.116199902 0.022621756 0.10189222 377922.8995 140.3994423 38080.69623 41483.03757 0.004274059 2.369159496 2.110641637 NSNS(ph)PPS(ph)PSSMNQR ddPTM_HeLa_Curcumin_4h_R1 3 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 2 0 NS(0.003)NS(0.997)PPS(0.989)PS(0.01)S(0.002)MNQR;NS(0.377)NS(0.623)PPS(0.999)PSS(0.001)MNQR;NS(0.004)NS(0.995)PPS(0.959)PS(0.035)S(0.007)MNQR ;; 228.49 5.32E-20 170756000 23748.8 20036.9 20714.2 21152.4 21427 24580.6 18000.3 10835 25219.9 20042.3 TRUE FALSE FALSE 21869.05742 21768.80035 21481.88647 21064.87697 21171.49702 19482.30648 18505.33997 14138.54162 22453.34007 20738.76843 1.054501259 1.049666976 1.035832313 1.015724586 1.020865684 0.939414823 0.892306601 0.681744515 1.082674708 1 14.3400426 -3.677836389 0.861524931 1.029547313 0.026589055 0.951301989 0.024734332 0.772312577 0.209876873 0.003792173 0.932445337 0.000209973 3.677836389 -1.002958258 TEEARPSPAPGPGT(ph)PT(ph)GTPTR ddPTM_HeLa_Curcumin_4h_R1 1 TEEARPSPAPGPGTPTGTPTR 21 1 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 2 0 T(0.026)EEARPS(0.02)PAPGPGT(0.943)PT(0.645)GT(0.332)PT(0.034)R 65.817 0.0027816 26711000 2719.5 2232.1 2345.7 2604.5 3247.6 3807.5 2079 710.36 2816.7 2126.8 TRUE FALSE FALSE 2504.248705 2425.032778 2432.633705 2593.723269 3208.874491 3017.781581 2137.331145 926.9454939 2507.715057 2200.706142 1.137929621 1.101933935 1.105387793 1.178586827 1.458111299 1.371278756 0.971202426 0.421203666 1.13950473 1 11.1037508 -4.305150491 3.587645988 1.125540196 0.370312598 0.721209406 0.139405426 0.120317245 2.714005436 0.022620632 0.224930961 4.95E-05 4.305150491 -0.755227598 down NSNSPPS(ph)PSSMNQR ddPTM_HeLa_Curcumin_4h_R1 5 NSNSPPSPSSMNQR 14 0 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 0 NS(0.001)NS(0.019)PPS(0.912)PS(0.053)S(0.016)MNQR;NSNS(0.007)PPS(0.892)PS(0.087)S(0.014)MNQR;NSNS(0.002)PPS(0.971)PS(0.025)S(0.002)MNQR;NS(0.407)NS(0.135)PPS(0.44)PS(0.013)S(0.004)MNQR;NS(0.001)NS(0.003)PPS(0.44)PS(0.44)S(0.117)MNQR ;;;; 273.44 3.93E-51 231453500 11190.6 9970.5 9129.9 10141.7 10411.4 11986.9 8127.6 6739.7 10683.5 10042.9 TRUE FALSE FALSE 10304.8522 10832.30559 9468.262125 10099.73633 10287.25085 9500.68182 8355.638582 8794.603504 9511.546779 10391.89003 0.991624447 1.042380699 0.911120316 0.971886375 0.989930689 0.914240027 0.804053792 0.846294897 0.91528555 1 13.34317045 -5.0051856 2.691014329 0.990897401 0.824345792 0.666954056 0.040647668 0.08222655 1.18243498 0.00459774 0.015846785 9.88E-06 5.0051856 -0.166551609 NSPAT(ph)LFEVPDTW ddPTM_HeLa_Curcumin_4h_R1 1 NSPATLFEVPDTW 13 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;O95453-4 O95453 PARN Poly(A)-specific ribonuclease PARN 1 0 NS(0.097)PAT(0.903)LFEVPDTW 143.76 0.00097265 0 0 0 0 131.57 174.92 116.04 0 0 0 121.8 TRUE FALSE FALSE 0 0 0 131.0255982 172.8341932 91.97199596 0 0 0 126.0325409 0 0 0 1.039617207 1.371345781 0.72974801 0 0 0 1 6.977652468 -9.574041684 1.390290316 0.996117735 0.36319347 0 0.566134103 0.632819385 2.214162373 0.367124318 0.088231703 2.67E-10 9.574041684 -0.632924265 TAPAAPAEDAVAAAAAAPSEPSEPS(ph)RPSPQPK ddPTM_HeLa_Curcumin_4h_R1 1 TAPAAPAEDAVAAAAAAPSEPSEPSRPSPQPK 32 1 Q53GA4 Q53GA4 PHLDA2 Pleckstrin homology-like domain family A member 2 1 0 TAPAAPAEDAVAAAAAAPS(0.168)EPS(0.117)EPS(0.357)RPS(0.357)PQPK 126.45 1.71E-13 6094400 5682.6 4834.4 5237.6 4988.5 5872 6506.1 4182.9 1770.8 4939.5 4736 TRUE FALSE FALSE 5232.816214 5252.263994 5431.710063 4967.858909 5801.980235 5156.661521 4300.260916 2310.708768 4397.649208 4900.575647 1.067796233 1.071764701 1.108382046 1.013729665 1.183938511 1.052256284 0.877501181 0.471517825 0.897374008 1 12.25873551 -4.304711163 2.25703166 1.051516204 0.356693347 0.859751918 0.070713241 0.113964436 0.7165964 0.008038354 0.150850633 4.96E-05 4.304711163 -0.694822857 down SVS(ph)KESVASMGADS(ph)GDDFASDGSSSR ddPTM_HeLa_Curcumin_4h_R1 1 SVSKESVASMGADSGDDFASDGSSSR 26 1 Q5T165;Q92805 Q5T165 GOLGA1 Golgin subfamily A member 1 2 0 S(0.109)VS(0.695)KES(0.192)VAS(0.166)MGADS(0.718)GDDFAS(0.024)DGS(0.063)S(0.012)S(0.022)R 50.644 0.013495 11569000 3085.2 2429.7 2510.3 2694 3127.8 2665.9 2011.8 860.52 2989.6 2500.2 TRUE FALSE FALSE 2841.003165 2639.712441 2603.333926 2682.852942 3090.503028 2112.962289 2068.245694 1122.888587 2661.64836 2587.081764 1.098149739 1.020343647 1.006282044 1.037018999 1.194590396 0.816735798 0.799451228 0.43403676 1.028822667 1 11.33710994 -4.304494741 1.185029943 1.048797588 0.192097715 0.863421642 0.075049877 0.363062634 0.438286435 0.011119606 0.374776805 4.96E-05 4.304494741 -0.856699873 down S(ph)LEEMSLR ddPTM_HeLa_Curcumin_4h_R1 2 SLEEMSLR 8 0 Q92614;A0A0D9SFK2;Q92614-3;Q92614-4 Q92614 MYO18A Unconventional myosin-XVIIIa 1 0 S(1)LEEMSLR;S(1)LEEMSLR ; 119.53 0.0054476 6670000 1784.39 1487.49 1650.9 1804.05 2287 2603.73 1448.57 450.55 1689.83 1650.76 TRUE FALSE FALSE 1643.153649 1616.062007 1712.083806 1796.585319 2259.729019 2063.687048 1489.212976 587.9206209 1504.459877 1708.123787 0.961964034 0.946103567 1.002318344 1.051788713 1.322930478 1.208160125 0.871841366 0.344190875 0.880767476 1 10.73819682 -4.304277633 3.41863653 1.022407756 0.28759832 0.734622114 0.126035215 0.109302243 2.154523859 0.018224655 0.194249258 4.96E-05 4.304277633 -0.734809436 down NSPGLLVS(ph)PGNLNK ddPTM_HeLa_Curcumin_4h_R1 1 NSPGLLVSPGNLNK 14 0 Q06413-5;A0A0D9SGI5;Q06413-6;A0A0D9SFD0;A0A0D9SGF3;A0A1B0GV32;A0A0R4J2G5;D8L7E9;D6RC63;Q06413-4;Q06413-3;Q06413-2;Q06413;D6RJG6;A0A0D9SFV9 Q06413-5 MEF2C Myocyte-specific enhancer factor 2C 1 0 NS(0.307)PGLLVS(0.693)PGNLNK 115.78 0.002141 30475000 2089.1 1921.7 1895.5 2100.6 1913.9 2141.1 2071.5 915.95 2030.6 1518.5 TRUE FALSE FALSE 1923.745531 2087.803185 1965.748897 2091.908274 1891.077993 1697.011725 2129.620715 1195.218938 1807.84826 1571.267762 1.224326991 1.328738001 1.251059142 1.331350598 1.20353643 1.080027075 1.35535188 0.760671712 1.150566634 1 10.61771334 -3.089856286 13.91143843 1.148755617 1.15756591 0 0.174659333 0 0 0.02328901 0 0.0008131 3.089856286 0.008810293 NSPGSQVASNPR ddPTM_HeLa_Curcumin_4h_R1 1 NSPGSQVASNPR 12 0 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 0 0 116.54 0.0013376 464290 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 NSPLDCGSAS(ph)PNK ddPTM_HeLa_Curcumin_4h_R1 1 NSPLDCGSASPNK 13 0 H0YM23;O75179-6;O75179-7;O75179-2;O75179;O75179-4 H0YM23 ANKRD17 Ankyrin repeat domain-containing protein 17 1 0 NSPLDCGS(0.227)AS(0.773)PNK 179.55 0.00016086 13380000 1842.5 2326.6 2119.6 2253.7 2875.1 2523.4 1862.2 1526.6 1853.8 1780.6 TRUE FALSE FALSE 1696.664181 2527.700937 2198.154241 2244.374787 2840.81631 2000.018395 1914.44832 1992.053312 1650.442778 1842.475717 0.920861081 1.371904613 1.193043805 1.218129914 1.541847354 1.085505972 1.039062986 1.08118294 0.895774507 1 10.84742989 -7.277855154 24.9052854 0.962628837 1.218062417 0.442370439 0.143209189 567.3917336 860819.4399 0.024997878 0.028630269 5.27E-08 7.277855154 0.25543358 NSPNNISGISNPPGT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 NSPNNISGISNPPGTPR 17 0 Q9NW25;Q9BWW4-2;Q9BWW4-3;Q9BWW4;A0A087WVT6 Q9NW25 SSBP3 Single-stranded DNA-binding protein 3 1 0 NSPNNISGISNPPGT(1)PR;NSPNNISGISNPPGT(1)PR;NSPNNISGISNPPGT(1)PR;NSPNNIS(0.001)GISNPPGT(0.998)PR ;;; 298.96 1.67E-94 73486500 4710.54 3644.77 4708.1 4430.06 4744.37 4962.32 4177.34 9783.4 4385.03 3428.81 TRUE FALSE FALSE 4337.695788 3959.807678 4882.586328 4411.729586 4687.796486 3933.078895 4294.544918 12766.31362 3904.00318 3547.960892 1.222588388 1.116079855 1.376166896 1.243454965 1.321264983 1.108546293 1.210426227 3.598211483 1.100351244 1 11.79277439 -4.261428565 6.227050355 1.153013244 3.655807855 0.97739324 0.109845323 0.01488143 3.05895181 0.018469245 0.156548172 5.48E-05 4.261428565 2.502794611 SLDSDES(ph)EDEEDDYQQK ddPTM_HeLa_Curcumin_4h_R1 2 SLDSDESEDEEDDYQQK 17 0 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 1 0 SLDSDES(1)EDEEDDYQQK;SLDSDES(1)EDEEDDYQQK ; 349.18 1.36E-172 35994000 5574.2 4318.4 3956.4 5049.9 4987.2 6197.9 5749.3 10126.4 5227.2 4422.5 TRUE FALSE FALSE 5132.996188 4691.663254 4103.027664 5029.004852 4927.730897 4912.385675 5910.609885 13213.89274 4653.789238 4576.181546 1.121676694 1.025235386 0.896605089 1.098952216 1.076821548 1.073468267 1.291603016 2.887536828 1.01695905 1 12.15992857 -4.245701469 3.004979257 1.05100822 3.225877497 0.98771946 0.061460293 0.034276511 0.436533538 0.009825529 0.181065357 5.68E-05 4.245701469 2.174869277 up DIS(ph)LDSELHDLR ddPTM_HeLa_Curcumin_4h_R1 2 DISLDSELHDLR 12 0 H0YJ97;Q15643-2;Q15643 H0YJ97 TRIP11 Thyroid receptor-interacting protein 11 1 0 DIS(0.999)LDS(0.001)ELHDLR;DIS(0.999)LDS(0.001)ELHDLR ; 133.48 0.0009558 26839000 8467 6865.8 7406.1 7057.5 8192.7 11490.5 6378.4 2020.55 9425.9 7102.5 TRUE FALSE FALSE 7796.828016 7459.249159 7680.576581 7028.297935 8095.007403 9107.240775 6557.360737 2636.606394 8391.902352 7349.311346 1.060892327 1.014958927 1.045074323 0.956320613 1.101464753 1.239196483 0.892241521 0.358755572 1.141862408 1 12.84339336 -4.302501176 3.437253572 1.041405798 0.301384593 0.872566031 0.080990303 0.061103935 1.224776256 0.010310758 0.110051543 4.98E-05 4.302501176 -0.740021205 down NSPQSSPTS(ph)TPK ddPTM_HeLa_Curcumin_4h_R1 1 NSPQSSPTSTPK 12 0 Q9Y6Y0 Q9Y6Y0 IVNS1ABP Influenza virus NS1A-binding protein 1 0 NSPQSSPT(0.01)S(0.76)T(0.23)PK 113.52 0.0045322 891530 1139.7 1052.9 928.04 1343.9 1058.2 981.28 672.72 423.46 969.69 933.6 TRUE FALSE FALSE 1049.491542 1143.907984 962.4339788 1338.339298 1045.581656 777.7514667 691.5947127 552.5710046 863.317433 966.0425305 1.086382337 1.184117622 0.996264604 1.385383413 1.082335014 0.805090296 0.715905036 0.57199449 0.893664001 1 9.915942896 -5.031657899 2.432637249 1.077983505 0.637629337 0.6749278 0.127756321 0.12609373 1.456909284 0.017338662 0.06104296 9.30E-06 5.031657899 -0.440354168 EDKS(ph)PSEESAPTTSPESVSGSVPSSGSSGR ddPTM_HeLa_Curcumin_4h_R1 1 EDKSPSEESAPTTSPESVSGSVPSSGSSGR 30 1 P54725-2;P54725-3;P54725;A0A494C0B4 P54725-2 RAD23A UV excision repair protein RAD23 homolog A 1 0 EDKS(0.425)PS(0.425)EES(0.146)APT(0.002)T(0.001)S(0.001)PESVSGSVPSSGSSGR 54.086 0.0014655 9080800 1270.4 1360.8 1232.5 795.25 1407.5 1607.4 1374.6 2612.2 913.43 1098.9 TRUE FALSE FALSE 1169.846499 1478.421488 1278.177534 791.9594662 1390.716482 1274.007121 1413.167576 3408.647755 813.2290143 1137.086693 1.028810298 1.300183616 1.124080989 0.696481166 1.223052288 1.120413359 1.242796688 2.997702616 0.715186467 1 10.15112654 -4.245670747 3.268709246 1.041869013 3.308804372 0.909946482 0.184840799 0.060086839 0.990910661 0.020865419 0.349395419 5.68E-05 4.245670747 2.266935359 up NSPTPATSTESLS(ph)PLHNVALR ddPTM_HeLa_Curcumin_4h_R1 1 NSPTPATSTESLSPLHNVALR 21 0 G5EA48;Q7Z6B7-2;Q7Z6B7 G5EA48 SRGAP1 SLIT-ROBO Rho GTPase-activating protein 1 1 0 NSPTPATSTES(0.444)LS(0.555)PLHNVALR 98.968 9.46E-05 4535000 1065.2 1211.5 1301.8 1059.4 1230.5 1915.3 1215.9 1084.7 1585.7 1567 TRUE FALSE FALSE 980.888296 1316.216662 1350.045853 1055.016484 1215.827091 1518.04519 1250.014882 1415.420037 1411.752677 1621.453133 0.60494397 0.811751283 0.832614786 0.650661103 0.749837949 0.936225142 0.77092261 0.872933055 0.870671281 1 10.66307161 -9.60743675 1.424674832 0.999382721 0.756398786 0.223305169 0.101549732 0.324058292 1.185355077 0.074210118 0.017287261 2.47E-10 9.60743675 -0.242983935 NSPVT(ph)KTPPRDLPTIPGVT(ph)SPSSDEPPMEASQSHLR ddPTM_HeLa_Curcumin_4h_R1 1 NSPVTKTPPRDLPTIPGVTSPSSDEPPMEASQSHLR 36 2 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 0 NS(0.191)PVT(0.324)KT(0.296)PPRDLPT(0.296)IPGVT(0.414)S(0.414)PS(0.05)S(0.015)DEPPMEASQSHLR 40.671 0.010525 29022000 521.82 455.2 318.35 395.48 541.25 801.41 341.79 179.56 454.97 431.44 TRUE FALSE FALSE 480.5173964 494.5454597 330.148331 393.8436085 534.7959473 635.1885322 351.3797075 234.3070174 405.0609293 446.4325079 1.076349477 1.107772062 0.739525741 0.882201904 1.197932359 1.422809766 0.787083605 0.524843091 0.907328481 1 8.802298274 -4.527532403 24.99751472 1.044178315 0.590403086 0.45896442 0.177794402 67.72514412 363794.7743 0.024120602 0.090951883 2.97E-05 4.527532403 -0.453775229 NSQDDYDEER ddPTM_HeLa_Curcumin_4h_R1 1 NSQDDYDEER 10 0 O76094-2;O76094;R4GNC1;D6RDY6 O76094-2 SRP72 Signal recognition particle subunit SRP72 0 0 128.01 1.75E-08 0 445.86 309.77 386.81 385.99 394.7 386.69 397.11 300.69 301.3 194.06 FALSE FALSE TRUE 410.5697105 336.5451385 401.1455189 384.3928757 389.9934603 306.4861351 408.2518378 392.3689968 268.2481438 200.8035706 2.044633516 1.675991804 1.997701125 1.914273111 1.942163973 1.526298234 2.033090531 1.953994123 1.335873377 1 7.649641112 -9.326913648 0.854747158 0.950402841 1.891104899 0.696774468 0.184513929 0.217838285 0.2606325 0.138855466 0.029902642 4.71E-10 9.326913648 0.940702058 NSQEDS(ph)EDS(ph)EDKDVK ddPTM_HeLa_Curcumin_4h_R1 1 NSQEDSEDSEDKDVK 15 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 2 0 NSQEDS(1)EDS(1)EDKDVK 134.08 0.0025811 1677300000 4249.4 21047 4746.1 8575.7 4843 5537.2 4586.5 5457.2 6274.1 7394.6 TRUE FALSE FALSE 3913.055506 22866.2089 4921.994641 8540.216026 4785.250388 4388.722303 4715.184846 7121.075158 5585.846927 7651.5618 0.511406117 2.988436805 0.643266665 1.11614024 0.625395248 0.573572091 0.616238223 0.930669495 0.730027029 1 12.90153854 -5.747227184 24.25213605 0.960011351 0.673388165 0.06089992 0.676511516 534.4432382 911981.9196 0.100669673 0.200502546 1.79E-06 5.747227184 -0.286623186 NSQEDS(ph)EDSEDKDVK ddPTM_HeLa_Curcumin_4h_R1 3 NSQEDSEDSEDKDVK 15 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 NSQEDS(0.999)EDS(0.001)EDKDVK;NS(0.001)QEDS(0.993)EDS(0.006)EDKDVK;NS(0.004)QEDS(0.988)EDS(0.008)EDKDVK ;; 96.455 0.002263 3723559000 9202.4 8754.3 9059 9419.6 9242.7 9712.6 9056.9 9312.5 10751.4 10055 TRUE FALSE FALSE 8474.02033 9510.982684 9394.734509 9380.624191 9132.486839 7698.097276 9311.012239 12151.83838 9571.998319 10404.4105 0.814464244 0.914129895 0.902956925 0.901600738 0.877751492 0.739887885 0.894910119 1.167950686 0.919994296 1 13.34490761 -4.261447808 15.06309129 0.894838865 1.167981951 0.623671741 0.065526556 0.031413959 3330.122608 0.011528532 0.08856536 5.48E-05 4.261447808 0.273143087 NSQEDSEDS(ph)EDKDVK ddPTM_HeLa_Curcumin_4h_R1 1 NSQEDSEDSEDKDVK 15 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 NSQEDS(0.395)EDS(0.605)EDKDVK 74.657 0.0099038 14474000 2707.7 3258.7 2907 3074.8 2652.9 2774.5 2280.9 3528.7 3454.3 3152.6 TRUE FALSE FALSE 2493.382688 3540.367508 3014.735977 3062.077292 2621.2659 2199.037425 2344.895915 4604.584386 3075.371932 3262.152615 0.764336615 1.085285676 0.924155407 0.9386677 0.803538709 0.674106237 0.718818581 1.411517157 0.942743119 1 11.67160856 NSQEDSEDSEDKDVK ddPTM_HeLa_Curcumin_4h_R1 2 NSQEDSEDSEDKDVK 15 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 0 0 ; ; 147.7 0.00040197 17151700 4897.1 4059.6 3933.1 3987.8 4916.6 5200 4485.8 4008.7 5107.7 3702.38 FALSE FALSE TRUE 4509.489368 4410.493735 4078.864146 3971.29954 4857.972756 4121.461384 4611.659475 5230.934176 4547.398089 3831.037429 1.177093529 1.151253105 1.064689192 1.036612044 1.26805672 1.075808175 1.203762573 1.365409311 1.186988687 1 11.90351941 -1 0.020479275 7.47E-15 2.639814636 0.164310874 0.097341511 2078.545233 3.31351971 157.8889528 287.5632812 0.1 1 2.639814636 LAS(ph)PELER ddPTM_HeLa_Curcumin_4h_R1 4 LASPELER 8 0 P05412;P17535 P05412;P17535 JUN;JUND Transcription factor AP-1;Transcription factor jun-D 1 0 LAS(1)PELER;LAS(1)PELER;LAS(1)PELER;LAS(1)PELER ;;; 133.99 0.0044108 763440000 20193.7 17229.8 17946.8 19600 18417.3 24371.5 24842.7 51292 21941.6 18461.1 TRUE FALSE FALSE 18595.34734 18719.06714 18611.9242 19518.90039 18197.68573 19316.57618 25539.7193 66930.69468 19534.66138 19102.62185 0.97344477 0.979921358 0.974312549 1.021791697 0.952627648 1.01120026 1.336974553 3.503743895 1.022616766 1 14.22148304 -4.245523856 2.934889769 0.988225128 3.986228279 0.99879324 0.026034009 0.012179622 0.144466213 0.004606305 0.087361246 5.68E-05 4.245523856 2.998003151 up NSS(ph)FSTAR ddPTM_HeLa_Curcumin_4h_R1 1 NSSFSTAR 8 0 H0Y507;Q5TCZ1-2;Q5TCZ1-3;Q5TCZ1 H0Y507 SH3PXD2A SH3 and PX domain-containing protein 2A 1 0 NS(0.009)S(0.809)FS(0.182)TAR 104.07 0.013028 58290000 3476.8 3117.2 3455.6 3551 3240.8 4113.5 3274.2 1844.3 4056.6 3790.1 TRUE FALSE FALSE 3201.607611 3386.636878 3583.667576 3536.306903 3202.155577 3260.313731 3366.06524 2406.61858 3611.601129 3921.805693 0.816360591 0.863540201 0.913779992 0.901703751 0.816500313 0.831329746 0.858294751 0.613650642 0.920902618 1 11.93730234 -13.52287874 0.025903238 2.130556869 7.80E-14 0.488516449 0.068915331 1030.4137 2.147510999 126.8517014 61.04804406 3.00E-14 13.52287874 -2.130556869 NSS(ph)PAPPQPAPGK ddPTM_HeLa_Curcumin_4h_R1 3 NSSPAPPQPAPGK 13 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 0 NS(0.029)S(0.971)PAPPQPAPGK;NS(0.004)S(0.996)PAPPQPAPGK;NS(0.052)S(0.948)PAPPQPAPGK ;; 143.56 0.00083658 141708000 21299.5 18900.7 21867.1 20347.4 25735.9 21387.4 20439.3 15787.1 16755.2 16717.7 TRUE FALSE FALSE 19613.6221 20534.39229 22677.51396 20263.20785 25429.0162 16951.41215 21012.77175 20600.51412 14917.19648 17298.63883 1.133824591 1.187052489 1.310942103 1.171375855 1.47000099 0.979927515 1.214706657 1.190874861 0.862333541 1 14.0783709 -8.066355844 0.790539967 1.01919027 1.220310938 0.404989992 0.126839073 0.449278164 0.611367943 0.038242153 0.026738034 8.58E-09 8.066355844 0.201120668 NSS(ph)PGEASLLEK ddPTM_HeLa_Curcumin_4h_R1 3 NSSPGEASLLEK 12 0 Q76FK4-2;Q76FK4-4;Q76FK4 Q76FK4-2 NOL8 Nucleolar protein 8 1 0 NS(0.097)S(0.903)PGEASLLEK;NSS(0.992)PGEAS(0.007)LLEK;NS(0.019)S(0.934)PGEAS(0.048)LLEK ;; 192.4 4.57E-06 59945100 14665.3 14175.6 14555.9 13673.2 16335.2 15785.9 12548.2 6743.6 12848.4 11762.4 TRUE FALSE FALSE 13504.52603 15400.8757 15095.35446 13616.62392 16140.41341 12511.7264 12900.26872 8799.692596 11438.96267 12171.14252 1.109552863 1.265359901 1.240257801 1.118763 1.326121469 1.027982901 1.059906142 0.72299643 0.939842964 1 13.57117698 -4.154274998 2.200189909 1.10452835 0.546454551 0.507939783 0.117291587 0.677693616 2.869321416 0.017315308 0.81466851 7.01E-05 4.154274998 -0.558073799 NSSLGS(ph)PSNLCGS(ph)PPGSIR ddPTM_HeLa_Curcumin_4h_R1 1 NSSLGSPSNLCGSPPGSIR 19 0 Q9C0B0 Q9C0B0 UNK RING finger protein unkempt homolog 2 0 NS(0.008)S(0.127)LGS(0.867)PS(0.297)NLCGS(0.673)PPGS(0.028)IR 113.78 0.00084476 28490000 2724.5 2456.6 2615.9 2760.7 2644.4 3136.3 2206.9 1212.3 2887 2841.5 TRUE FALSE FALSE 2508.85295 2668.937558 2712.847555 2749.276955 2612.867257 2485.796027 2268.819674 1581.924689 2570.303323 2940.241913 0.853281133 0.907727199 0.922661344 0.935051277 0.888657238 0.845439287 0.771643879 0.538025352 0.8741809 1 11.52171914 -3.826748003 0.891896678 0.927266136 9.50E-19 0.896138469 0.038644843 1.232882131 0.431072722 0.008519854 1.338168532 0.000149023 3.826748003 -0.927266136 NSSLLS(ph)FDNEDENE ddPTM_HeLa_Curcumin_4h_R1 2 NSSLLSFDNEDENE 14 0 Q96AT1 Q96AT1 KIAA1143 Uncharacterized protein KIAA1143 1 0 NS(0.005)S(0.02)LLS(0.975)FDNEDENE;NS(0.004)S(0.029)LLS(0.966)FDNEDENE ; 186.29 4.00E-05 42426000 7137.6 4146 4477.4 5021.9 5855.4 21479 32737 14421.9 6393.1 4114.3 TRUE FALSE FALSE 6572.651428 4504.361766 4643.336383 5001.120708 5785.578179 17024.01328 33655.51211 18819.07092 5691.792925 4257.271619 1.543864714 1.058039554 1.090683611 1.174724367 1.358987327 3.998808346 7.9054181 4.420453428 1.3369579 1 12.05571342 -5.085938689 3.217199093 1.232522528 6.168413852 0.855390008 0.822596471 0.054388202 1.074479911 0.1023351 0.30559663 8.20E-06 5.085938689 4.935891325 NSSLLSFDNEDENE ddPTM_HeLa_Curcumin_4h_R1 4 NSSLLSFDNEDENE 14 0 Q96AT1 Q96AT1 KIAA1143 Uncharacterized protein KIAA1143 0 0 ;;; ;;; 257.72 6.42E-38 63316000 30522.9 25228.9 23283.8 27350.2 27395.4 31455.3 23242.4 24536.5 29758.5 26193.1 FALSE FALSE TRUE 28106.98026 27409.5737 24146.71811 27237.03212 27068.72775 24931.11621 23894.51919 32017.5659 26494.067 27103.30828 1.037031346 1.011299928 0.890914049 1.004933857 0.998724122 0.919855095 0.881608951 1.181315785 0.977521516 1 14.72618134 -6.969049766 24.99287751 1.017838575 0.97247465 0.01449764 0.080837381 418.4875238 337935.3807 0.011976498 0.015740086 1.07E-07 6.969049766 -0.045363924 NSSNKPAVTTK(ac)SPAVKPAAAPK ddPTM_HeLa_Curcumin_4h_R1 2 NSSNKPAVTTKSPAVKPAAAPK 22 3 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 1 ; NSSNKPAVTTK(1)SPAVKPAAAPK;NSSNKPAVTTK(1)SPAVKPAAAPK 220.82 3.15E-30 82084000 11663.9 10051.9 10772.2 10749.1 9798.6 12057.3 10033.4 8271.3 10281.7 10015.2 FALSE TRUE FALSE 10740.69001 10920.74145 11171.42721 10704.62307 9681.758095 9556.480066 10314.9102 10793.18129 9153.823234 10363.22745 1.036423262 1.053797332 1.077987264 1.032942982 0.93424159 0.922152882 0.995337625 1.041488411 0.883298497 1 13.33918576 -5.783154562 24.97223291 1.026699716 0.97122514 0.081316043 0.058368841 219.2723514 252160.4686 0.006063895 0.010998495 1.65E-06 5.783154562 -0.055474576 NSSNKPAVTTKS(ph)PAVKPAAAPK ddPTM_HeLa_Curcumin_4h_R1 1 NSSNKPAVTTKSPAVKPAAAPK 22 3 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 0 NS(0.002)S(0.002)NKPAVT(0.039)T(0.391)KS(0.566)PAVKPAAAPK 61.139 0.0041329 106490000 1834 1640.7 1473.7 1681.1 1728.3 2826.3 2425.5 894.43 2296.9 1539.4 TRUE FALSE FALSE 1688.836965 1782.514797 1528.316618 1674.144054 1707.691151 2240.093521 2493.553002 1167.13759 2044.935817 1592.894035 1.060231834 1.119041667 0.959459063 1.051007799 1.072068269 1.406304168 1.565423027 0.732715148 1.283786474 1 10.63743458 -5.413659751 6.456998329 1.033422441 1.266914416 0.07103808 0.217180092 0.262123483 13.51788255 0.026282731 0.059146308 3.86E-06 5.413659751 0.233491976 NSSNTSVGS(ph)PSNTIGR ddPTM_HeLa_Curcumin_4h_R1 3 NSSNTSVGSPSNTIGR 16 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 0 NSSNT(0.001)S(0.002)VGS(0.98)PS(0.01)NT(0.007)IGR;NSSNTSVGS(0.997)PS(0.003)NTIGR;NSSNTSVGS(0.965)PS(0.034)NTIGR ;; 255.72 2.96E-40 378166000 7121.3 5403.9 5890.3 6511.4 6701 6762 5005.9 2381.73 6634.2 5914.3 TRUE FALSE FALSE 6557.641591 5870.989037 6108.5997 6484.457552 6621.094952 5359.484977 5146.352081 3107.908513 5906.444858 6119.821485 1.07154132 0.959339917 0.998166321 1.059582795 1.081909818 0.875758384 0.840931732 0.507843002 0.965133521 1 12.57927385 -4.002605933 1.045702594 1.030542681 2.86E-18 0.898167943 0.05148221 0.561806615 0.337367056 0.007508722 0.730268722 9.94E-05 4.002605933 -1.030542681 NSSQDDLFPTS(ph)DTPR ddPTM_HeLa_Curcumin_4h_R1 1 NSSQDDLFPTSDTPR 15 0 Q9H6T3-3;Q9H6T3-2;Q9H6T3 Q9H6T3-3 RPAP3 RNA polymerase II-associated protein 3 1 0 NSSQDDLFPT(0.159)S(0.553)DT(0.288)PR 110.57 0.0021695 9511800 1041.8 950.43 853.81 848.56 1279.4 1812.7 1854.9 762.83 1386.7 809.78 TRUE FALSE FALSE 959.3404307 1032.580934 885.4529497 845.0488836 1264.143991 1436.725587 1906.943502 995.4133554 1234.582479 837.9197947 1.144907229 1.232314764 1.056727571 1.00850808 1.508669444 1.714633782 2.275806723 1.187957799 1.473389801 1 9.710668346 -5.565350507 2.915636252 1.078686466 1.774204136 0.442726505 0.282956267 0.122633288 2.114392432 0.034184164 0.076866228 2.72E-06 5.565350507 0.695517669 NSSQDDLFPTSDT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 NSSQDDLFPTSDTPR 15 0 Q9H6T3-3;Q9H6T3-2;Q9H6T3 Q9H6T3-3 RPAP3 RNA polymerase II-associated protein 3 1 0 NSSQDDLFPT(0.265)S(0.08)DT(0.655)PR 174.4 1.18E-14 0 2213.5 1816.5 2377.8 2406 2352.7 3476.4 2958.9 1475.5 2557.9 1766.5 TRUE FALSE FALSE 2038.299139 1973.510166 2465.92336 2396.04461 2324.645589 2755.355453 3041.918771 1925.373158 2277.30477 1827.885744 1.115112991 1.07966823 1.349057712 1.310828436 1.271767449 1.507400264 1.664173366 1.053333429 1.245868227 1 10.83596018 -6.703689584 0.776892799 1.03535466 1.416075542 0.295847295 0.167667698 0.347690714 0.422499283 0.031849672 0.054633565 1.98E-07 6.703689584 0.380720882 NSSQSLMVPQSGS(ph)PEPESIR ddPTM_HeLa_Curcumin_4h_R1 4 NSSQSLMVPQSGSPEPESIR 20 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970;B7ZB24;H0YGQ3;A0A075B6R8 F5H1U9 MPDZ Multiple PDZ domain protein 1 0 NSSQSLMVPQS(0.087)GS(0.913)PEPESIR;NSSQSLMVPQS(0.169)GS(0.831)PEPESIR;NSSQSLMVPQS(0.023)GS(0.976)PEPES(0.001)IR;NSSQSLMVPQS(0.026)GS(0.973)PEPESIR ;;; 233.87 1.13E-25 57179400 11231.05 8848.07 9536.11 9541.75 8789.86 10795.47 7244.37 5115.17 11944.93 8764.91 TRUE FALSE FALSE 10342.10054 9612.857745 9889.526625 9502.268767 8685.04666 8556.367832 7447.627525 6674.761786 10634.60106 9069.48997 1.140317766 1.059911613 1.090417064 1.047718096 0.957611364 0.943423264 0.821173798 0.735957789 1.17256881 1 13.14680571 -4.756818003 0.879505594 1.069404121 0.670563245 0.857439122 0.049245346 0.372050334 0.332069628 0.008833033 0.120527628 1.75E-05 4.756818003 -0.398840876 SSDPGPDIGVVEES(ph)PEKGDEISLRR ddPTM_HeLa_Curcumin_4h_R1 1 SSDPGPDIGVVEESPEKGDEISLRR 25 2 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 0 SSDPGPDIGVVEES(1)PEKGDEISLRR 77.907 6.16E-05 14173000 2383.8 2260.1 2203.8 2324.4 2349.1 2921.7 1683.9 378.41 2957.1 2505.1 TRUE FALSE FALSE 2195.119715 2455.452973 2285.474767 2314.782249 2321.088517 2315.706486 1731.145702 493.785467 2632.713528 2592.152039 0.846832933 0.947264256 0.881690091 0.892996327 0.895429158 0.893352879 0.667841113 0.190492479 1.015647805 1 11.33993462 -4.302021687 1.823986464 0.919808852 5.31E-13 0.952967136 0.049792054 0.132403408 0.471269701 0.00834373 0.202044272 4.99E-05 4.302021687 -0.919808852 down NSSS(ph)PVSLDAALPESSNVYRDPSAK ddPTM_HeLa_Curcumin_4h_R1 2 NSSSPVSLDAALPESSNVYRDPSAK 25 1 H7C296;R4GN32;H7C1E9;Q70EL1-6;Q70EL1-7;Q70EL1 H7C296 USP54 Inactive ubiquitin carboxyl-terminal hydrolase 54 1 0 NS(0.034)S(0.148)S(0.67)PVS(0.148)LDAALPESSNVYRDPSAK;NS(0.045)S(0.183)S(0.771)PVS(0.002)LDAALPESSNVYRDPSAK ; 79.365 0.00016672 6062900 3322.11 2712.43 3061.33 3363.42 2869.83 3276.9 1809.35 1432.14 3363.88 2768.15 TRUE FALSE FALSE 3059.161488 2946.880363 3174.785583 3349.503059 2835.609152 2597.234002 1860.115491 1868.792893 2994.87078 2864.343006 1.068015067 1.028815458 1.108381774 1.169379174 0.989968431 0.906746851 0.64940389 0.652433347 1.045569882 1 11.48398855 -4.914588166 2.153119437 1.047040936 0.632490065 0.910265553 0.050655093 0.074499128 0.667103531 0.008271151 0.035860815 1.22E-05 4.914588166 -0.41455087 NSSSSGTSLLT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 NSSSSGTSLLTPK 13 0 Q9NXV6 Q9NXV6 CDKN2AIP CDKN2A-interacting protein 1 0 NSSSSGTSLLT(1)PK 110.55 0.011397 11048000 2179.8 2030.5 1918.6 2176 2192.3 3654.9 3998.8 1843 2457.6 1667.8 TRUE FALSE FALSE 2007.26653 2206.007372 1989.705004 2166.996289 2166.158254 2896.832541 4110.995566 2404.922216 2188.007429 1725.755926 1.16312307 1.278284686 1.152946934 1.255679471 1.255193867 1.678587625 2.382141938 1.393547129 1.267854507 1 10.75301272 -5.243807138 2.686286955 1.116851289 1.91319533 0.575765751 0.242877681 0.11481487 1.632014886 0.03204123 0.090375707 5.70E-06 5.243807138 0.796344041 NSSSSSS(ph)PSERPR ddPTM_HeLa_Curcumin_4h_R1 1 NSSSSSSPSERPR 13 1 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 0 NSSS(0.001)S(0.002)S(0.14)S(0.85)PS(0.007)ERPR 77.324 0.01101 1704900 545.25 560.24 385.62 539.52 726.57 1087.2 443.07 471.36 650.02 484.03 TRUE FALSE FALSE 502.0928872 608.6646492 399.9114164 537.2876092 717.9061273 861.7024647 455.5013517 615.0754941 578.7144323 500.8500065 1.002481543 1.215263335 0.798465431 1.072751527 1.433375498 1.720480091 0.909456615 1.228063265 1.15546456 1 8.968234803 -5.885967762 5.905487645 1.00407845 1.320034436 0.288578792 0.214654773 0.181286058 8.759593097 0.030197936 0.05531647 1.30E-06 5.885967762 0.315955986 NSSSSTS(ph)PVSK ddPTM_HeLa_Curcumin_4h_R1 1 NSSSSTSPVSK 11 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 NSSS(0.001)S(0.037)T(0.221)S(0.697)PVS(0.044)K 88.224 0.019325 3508700 4341.6 6066.9 4444.9 3166.4 3068.7 3112.7 2212.3 1453.4 3090.9 3108.1 TRUE FALSE FALSE 3997.957779 6591.295802 4609.631904 3153.298276 3032.107757 2467.090933 2274.371184 1896.534969 2751.836003 3216.106244 1.243105008 2.049464571 1.433295903 0.980470804 0.94278843 0.767104923 0.707181608 0.589699104 0.855642132 1 11.65109935 -5.584941496 1.694549738 1.219140073 0.67748517 0.418613682 0.309601302 0.334639656 1.911244023 0.051053172 0.134652694 2.60E-06 5.584941496 -0.541654904 NSSTDQGS(ph)DEEGSLQK ddPTM_HeLa_Curcumin_4h_R1 2 NSSTDQGSDEEGSLQK 16 0 Q12789-3;Q12789 Q12789-3 GTF3C1 General transcription factor 3C polypeptide 1 1 0 NSSTDQGS(1)DEEGSLQK;NSSTDQGS(1)DEEGSLQK ; 302.9 7.81E-95 69614000 7255.6 7030.1 8360.3 7328 8988 8614.1 7741.2 3849.4 6416 6529.9 TRUE FALSE FALSE 6681.311604 7637.750518 8670.140072 7297.678678 8880.82397 6827.438559 7958.397238 5023.06434 5712.180852 6756.813539 0.988825808 1.130377577 1.283169947 1.080047368 1.314350902 1.010452415 1.177832893 0.743407275 0.845395662 1 12.72212733 -7.263124296 24.29259909 0.994723295 1.118644951 0.157026559 0.156642983 149.0923873 2149570.752 0.023492791 0.027610954 5.46E-08 7.263124296 0.123921656 NSSTDQGSDEEGS(ph)LQKEQESAMDK ddPTM_HeLa_Curcumin_4h_R1 1 NSSTDQGSDEEGSLQKEQESAMDK 24 1 Q12789-3;Q12789 Q12789-3 GTF3C1 General transcription factor 3C polypeptide 1 1 0 NSS(0.002)T(0.006)DQGS(0.153)DEEGS(0.716)LQKEQES(0.123)AMDK 63.376 0.0015087 21946000 1103.7 950.7 1090.6 961.88 1140.8 747.61 735.59 429.21 1249.9 843.3 TRUE FALSE FALSE 1016.34098 1032.874272 1131.018595 957.8999954 1127.196705 592.5472587 756.2286757 560.0741532 1112.789097 872.6046122 1.164721073 1.183668132 1.296140978 1.097748032 1.291761113 0.679055841 0.866633828 0.641841844 1.275250075 1 9.769184289 -5.250930512 24.86069813 1.118278678 0.742922809 0.748219567 0.11696838 295.1423749 698212.7735 0.016861588 0.042483609 5.61E-06 5.250930512 -0.375355869 NSSTDQGSDEEGS(ph)LQKEQESAMDKHNLER ddPTM_HeLa_Curcumin_4h_R1 1 NSSTDQGSDEEGSLQKEQESAMDKHNLER 29 2 Q12789-3;Q12789 Q12789-3 GTF3C1 General transcription factor 3C polypeptide 1 1 0 NS(0.001)S(0.001)T(0.002)DQGS(0.134)DEEGS(0.843)LQKEQES(0.019)AMDKHNLER 47.577 0.0065716 11532000 2109.1 2184.4 2145 1994.8 1950.2 2410.5 1983.9 1199.2 2150.4 2286.1 TRUE FALSE FALSE 1942.162509 2373.209803 2224.495587 1986.546046 1926.945139 1910.535128 2039.562895 1564.83056 1914.5065 2365.541805 0.821022273 1.00324154 0.940374667 0.839784798 0.81458934 0.807652236 0.862196935 0.661510423 0.809331078 1 11.20795494 -1 0.082825914 1.089184151 0.208018799 0.260396888 0.083873969 125.5089765 0.761688406 1.204700493 12.68797403 0.1 1 -0.881165352 NSSTYWEGK ddPTM_HeLa_Curcumin_4h_R1 2 NSSTYWEGK 9 0 P26639;P26639-2 P26639 TARS "Threonine--tRNA ligase, cytoplasmic" 0 0 ; ; 135.86 0.00028411 11088000 7898.5 5637.7 6182.2 7846.4 7222 4701.1 4880.9 4636.5 7018.3 5537.9 FALSE FALSE TRUE 7273.325391 6124.997667 6411.31777 7813.933676 7135.882367 3726.038868 5017.844918 6050.147506 6248.410049 5730.341613 1.269265583 1.068871296 1.118836922 1.363606955 1.245280447 0.650229798 0.87566244 1.05580922 1.09040795 1 12.48440543 -5.276393834 24.90909217 1.149766974 0.862076665 0.510581884 0.136081125 532.4004578 886799.6329 0.022130678 0.049673277 5.29E-06 5.276393834 -0.287690309 NSSYFVEWIPNNVK ddPTM_HeLa_Curcumin_4h_R1 3 NSSYFVEWIPNNVK 14 0 Q5JP53;P07437;Q5ST81;P04350;P68371;Q9BVA1;Q13885;A0A0B4J269;Q13509;Q13509-2;Q9BUF5;K7ESM5 Q5JP53;P04350;P68371;Q9BVA1;A0A0B4J269;Q9BUF5 TUBB;TUBB4A;TUBB4B;TUBB2B;TUBB2A;TUBB3;TUBB6 Tubulin beta chain;Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-2B chain;Tubulin beta-2A chain;Tubulin beta-3 chain;Tubulin beta-6 chain 0 0 ;; ;; 252.42 5.61E-139 49195000 7698.52 6528.42 6752.03 7330.06 7219.04 8010.83 6276.9 6844.91 7897.3 6899.16 FALSE FALSE TRUE 7089.174019 7092.707535 7002.266171 7299.730154 7132.957663 6349.293557 6453.012921 8931.891549 7030.985948 7138.905296 0.993033767 0.993528733 0.980859933 1.022527944 0.99916687 0.889393162 0.903921911 1.25115703 0.984882928 1 12.80148715 -4.250383381 24.9172666 0.985471335 1.25115719 0.792344816 0.042186368 576.5102916 1299274.839 0.006123369 0.124512965 5.62E-05 4.250383381 0.265685855 NST(ph)ELAPPLPVR ddPTM_HeLa_Curcumin_4h_R1 1 NSTELAPPLPVR 12 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 0 NS(0.248)T(0.752)ELAPPLPVR 188.09 3.23E-05 6632900 1436.1 1655.4 1699.6 1502.2 2041.3 1873.8 1768 511.64 1442.3 1244.9 TRUE FALSE FALSE 1322.43117 1798.4854 1762.588671 1495.984294 2016.958831 1485.152758 1817.605322 667.6366807 1284.083298 1288.160182 1.026604601 1.396165962 1.368299296 1.16133406 1.565767098 1.152925528 1.411008776 0.518287003 0.996835111 1 10.33109629 -7.363329304 8.033331458 1.011875371 1.245227459 0.11878465 0.266949506 0.407182208 28.93977751 0.042144454 0.04809665 4.33E-08 7.363329304 0.233352089 NSPFQIPPPS(ph)PDSK ddPTM_HeLa_Curcumin_4h_R1 2 NSPFQIPPPSPDSK 14 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2;Q86W92-3 PPFIBP1 Liprin-beta-1 1 0 NSPFQIPPPS(0.971)PDS(0.029)K;NSPFQIPPPS(0.733)PDS(0.267)K ; 94.639 0.0076517 65726000 15139 11310.3 12240.1 13200.8 13131.3 13511.4 8594.4 3254.2 15349.1 12921.8 TRUE FALSE FALSE 13940.73218 12287.91193 12693.72887 13146.17859 12974.71782 10708.98334 8835.535733 4246.3906 13665.34213 13370.83159 1.042622673 0.919008803 0.949359716 0.983198278 0.970374785 0.800921264 0.660806748 0.317586126 1.022026345 1 13.70680158 -4.300759507 0.937539068 1.007528032 5.49E-21 0.966707166 0.038919794 0.24789227 0.170005506 0.006648713 0.249677947 5.00E-05 4.300759507 -1.007528032 down RS(ph)SITEPEGPNGPNIQK ddPTM_HeLa_Curcumin_4h_R1 1 RSSITEPEGPNGPNIQK 17 1 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 0 RS(0.483)S(0.483)IT(0.034)EPEGPNGPNIQK 218.36 2.07E-15 11684000 3917.1 2248.6 3050.5 2875.6 3142.4 3815 2295.7 755.19 3575.9 2423.7 TRUE FALSE FALSE 3607.057402 2442.958964 3163.554213 2863.701529 3104.928932 3023.725996 2360.111163 985.4439545 3183.632716 2507.923395 1.438264586 0.974096326 1.261423782 1.141861644 1.238047757 1.205669201 0.941061903 0.392932239 1.269429809 1 11.29227757 -4.30004435 2.110064951 1.196445289 0.2102674 0.783173281 0.127551271 0.27389876 1.426562145 0.023781766 0.494875644 5.01E-05 4.30004435 -0.98617789 down NSTFSEIFK ddPTM_HeLa_Curcumin_4h_R1 1 NSTFSEIFK 9 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 0 110.76 0.0033747 1279100 751.38 776.2 801.04 874.62 747.32 515.66 484.03 493.81 918.96 619.48 FALSE FALSE TRUE 691.9074801 843.2912693 830.7272471 871.0010542 738.4086971 408.7063033 497.6105791 644.3703958 818.1523871 641.0068839 1.079407254 1.315572875 1.295972427 1.358801405 1.151951275 0.63760049 0.776295219 1.005247232 1.276355072 1 9.32419604 -5.27659621 24.65686412 1.110895607 0.803372401 0.523683684 0.157772696 499.201353 812091.6096 0.025254836 0.056686818 5.29E-06 5.27659621 -0.307523207 NSTFSEIFK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 NSTFSEIFKK 10 1 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 1 NSTFSEIFK(1)K 164.65 1.37E-10 5137200 738.07 1424.7 1074 922.83 2018.8 2989.4 1810.5 1943.3 2718 857.7 FALSE TRUE FALSE 679.6509807 1547.84472 1113.803385 919.011574 1994.727129 2369.364743 1861.297757 2535.803224 2419.8422 887.5050112 0.765799598 1.744040541 1.254982643 1.035500152 2.247567173 2.669691678 2.097225068 2.857226936 2.726567365 1 9.793611455 -5.730533707 0.832225552 0.923200174 2.697998215 0.19953477 0.669498473 0.227598321 0.287143004 0.06302907 0.233766086 1.86E-06 5.730533707 1.77479804 NSTFSEIFKK ddPTM_HeLa_Curcumin_4h_R1 1 NSTFSEIFKK 10 1 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 0 80.014 0.01168 8063200 4450 3261.4 4491.6 3641.6 4725.4 5701.5 4136.9 4295.4 3991.9 4307.9 FALSE FALSE TRUE 4097.777804 3543.300883 4658.062647 3626.532024 4669.052691 4518.944631 4252.97028 5605.047686 3553.998557 4457.599204 0.919279104 0.794889967 1.044971168 0.813561708 1.047436631 1.013761988 0.954094365 1.257414009 0.79728984 1 12.12205119 -1.791419164 1.274407945 0.950692397 199.9428399 0.490979446 0.096909794 570.3348288 1.811681244 0.011829219 330775.5079 0.016165191 1.791419164 198.9921475 NSTGGT(ph)SVGWDSPPASPLQR ddPTM_HeLa_Curcumin_4h_R1 1 NSTGGTSVGWDSPPASPLQR 20 0 Q13424-2;Q13424 Q13424-2 SNTA1 Alpha-1-syntrophin 1 0 NSTGGT(0.667)S(0.062)VGWDS(0.272)PPASPLQR 300.5 4.32E-98 14539000 2226.3 1974.9 1995.9 2264 2072.7 2289.2 1548 1561.2 2234 2112.3 TRUE FALSE FALSE 2050.086006 2145.601556 2069.86981 2254.632168 2047.984406 1814.394115 1591.432714 2037.202693 1988.935789 2185.702268 0.937953003 0.981653168 0.947004466 1.031536729 0.936991482 0.830119519 0.728110474 0.932058645 0.909975626 1 11.09388118 -5.317360035 3.782273543 0.972957842 0.818321798 0.544203128 0.056081289 0.104903323 3.055289894 0.007168057 0.017460434 4.82E-06 5.317360035 -0.154636043 NSTGGTSVGWDS(ph)PPAS(ph)PLQR ddPTM_HeLa_Curcumin_4h_R1 2 NSTGGTSVGWDSPPASPLQR 20 0 Q13424-2;Q13424 Q13424-2 SNTA1 Alpha-1-syntrophin 2 0 NSTGGT(0.001)S(0.005)VGWDS(0.994)PPAS(1)PLQR;NSTGGTSVGWDS(1)PPAS(1)PLQR ; 200.4 2.42E-11 35543000 5218.1 4594 5154.9 5442.1 5455.6 5764.5 5380.1 3840.3 5849.4 5040 TRUE FALSE FALSE 4805.081879 4991.08489 5345.945129 5419.582032 5390.545533 4568.877721 5531.051126 5011.189791 5207.735454 5215.139625 0.921371665 0.957037634 1.02508188 1.039201713 1.033633981 0.876079654 1.060575847 0.960892738 0.998580255 1 12.34849016 -6.783165661 24.39687288 0.961395064 0.999813123 0.063161026 0.053239684 322.8703203 362556.3188 0.008801888 0.01157434 1.65E-07 6.783165661 0.038418058 NSTGGTSVGWDS(ph)PPASPLQR ddPTM_HeLa_Curcumin_4h_R1 1 NSTGGTSVGWDSPPASPLQR 20 0 Q13424-2;Q13424 Q13424-2 SNTA1 Alpha-1-syntrophin 1 0 NSTGGTS(0.04)VGWDS(0.94)PPAS(0.019)PLQR 166.34 3.91E-06 38606000 699.07 678.79 678.36 742.9 718.44 1093.7 584.62 614.28 678.96 903.04 TRUE FALSE FALSE 643.7378718 737.461583 703.5006183 739.8260766 709.8730722 866.8542915 601.0228638 801.5711442 604.4797867 934.4205728 0.68891663 0.789218051 0.75287364 0.791748489 0.759693325 0.927691788 0.643203801 0.857826944 0.646903337 1 9.867928228 -9.430228013 1.124612968 1.001767993 0.768781399 0 0.13185856 0.279800634 0.625285736 0.051564858 0.012547718 3.71E-10 9.430228013 -0.232986594 NSTLPMEETS(ph)PCSSR ddPTM_HeLa_Curcumin_4h_R1 4 NSTLPMEETSPCSSR 15 0 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 0 NSTLPMEET(0.236)S(0.762)PCS(0.002)SR;NSTLPMEET(0.406)S(0.589)PCS(0.004)S(0.001)R;NSTLPMEET(0.004)S(0.995)PCS(0.001)S(0.001)R;NSTLPMEET(0.231)S(0.757)PCS(0.01)S(0.002)R ;;; 186.96 1.32E-05 49024000 12204 10225.3 10763.7 10023.2 10616.4 12219.4 7736 4615.1 12336.3 10491.2 TRUE FALSE FALSE 11238.04052 11109.12937 11162.61219 9981.726654 10489.80636 9684.958699 7953.05134 6022.222745 10983.03875 10855.76842 1.03521373 1.023338831 1.028265505 0.919485961 0.966288701 0.892148609 0.73261063 0.554748638 1.011723752 1 13.40617423 -3.91162528 0.699961905 1.017517442 0.008707408 0.969478003 0.026018731 0.495515451 0.121726443 0.004570707 0.442142924 0.000122567 3.91162528 -1.008810033 NSTPSEPGS(ph)GR ddPTM_HeLa_Curcumin_4h_R1 1 NSTPSEPGSGR 11 0 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 0 NST(0.024)PS(0.024)EPGS(0.951)GR 113.95 0.0052588 97692000 4341.5 3745 3992.9 4096.1 3937.5 3935.8 3187.1 3507.8 3862.9 3677.9 TRUE FALSE FALSE 3997.865694 4068.701113 4140.880387 4079.151424 3890.547884 3119.470714 3276.521448 4577.312072 3439.149534 3805.706751 1.050492315 1.069105262 1.088071325 1.07185122 1.022293135 0.819682366 0.860949533 1.202749547 0.903682222 1 11.89394868 -5.494075345 24.85911121 1.03694533 0.946089106 0.072915027 0.106431234 930.887022 803412.0988 0.01337412 0.029844968 3.21E-06 5.494075345 -0.090856224 NSTPSEPGS(ph)GRGPPQEEEEEEDEEEEATKEDAEAPGIR ddPTM_HeLa_Curcumin_4h_R1 2 NSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIR 38 2 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 0 NS(0.001)T(0.002)PS(0.032)EPGS(0.965)GRGPPQEEEEEEDEEEEAT(0.001)KEDAEAPGIR;NS(0.011)T(0.023)PS(0.277)EPGS(0.67)GRGPPQEEEEEEDEEEEAT(0.019)KEDAEAPGIR ; 63.008 3.73E-05 53274000 3227.31 2150.4 2501.84 3034.66 2150.72 2955.05 2716.48 2515.98 3626.71 2588.81 TRUE FALSE FALSE 2971.865008 2336.270994 2594.560391 3022.103381 2125.074069 2342.13932 2792.697118 3283.09072 3228.868987 2678.770955 1.10941363 0.872142872 0.968563731 1.128167892 0.793301893 0.87433355 1.042529266 1.225595908 1.205354635 1 11.38735552 -7.294301252 24.96018425 1.05166754 0.981569235 0.1072602 0.13170708 1451.781138 1102694.634 0.021498722 0.024585857 5.08E-08 7.294301252 -0.070098305 NSTPSEPGSGR ddPTM_HeLa_Curcumin_4h_R1 2 NSTPSEPGSGR 11 0 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 0 0 ; ; 133.91 0.00056397 8314100 4176.9 3594.1 3980.5 4485.9 4725.2 4681.2 4068.3 3726.1 4456.5 3976.4 FALSE FALSE TRUE 3846.293958 3904.757989 4128.020832 4467.338534 4668.855076 3710.266352 4182.445549 4862.170737 3967.6331 4114.579604 0.934796341 0.949005333 1.003266732 1.085733894 1.13471011 0.901736437 1.016494017 1.1816932 0.964286387 1 12.00652932 -6.488259127 4.700838581 0.96703471 1.055936895 0.310847219 0.071231979 0.222804857 11.79572914 0.011325916 0.017080639 3.25E-07 6.488259127 0.088902185 NSTWSGESK ddPTM_HeLa_Curcumin_4h_R1 2 NSTWSGESK 9 0 P19338 P19338 NCL Nucleolin 0 0 ; ; 180.09 2.40E-16 23767000 8223.9 7436.1 7887.3 6410.9 7020.3 8743.4 7322.4 6323.4 7218.7 7639.9 FALSE FALSE TRUE 7572.969637 8078.843349 8179.610276 6384.373394 6936.587508 6929.920282 7527.846837 8251.375551 6426.82667 7905.385956 0.957950653 1.021941673 1.03468829 0.807597938 0.877450835 0.876607457 0.952242797 1.043766313 0.812968109 1 12.94862018 -6.292289965 24.99412865 0.9871578 0.9099609 0.068354851 0.081956261 698.9917248 566298.5026 0.009674395 0.014778701 5.10E-07 6.292289965 -0.0771969 SES(ph)PVCSSR ddPTM_HeLa_Curcumin_4h_R1 1 SESPVCSSR 9 0 O00472;D6RC27 O00472 ELL2 RNA polymerase II elongation factor ELL2 1 0 S(0.006)ES(0.993)PVCS(0.001)SR 123.62 0.0052982 72002000 2350.9 2306.4 2250.1 2025.2 1733 2682.7 1418.4 476.25 2660.7 2216.6 TRUE FALSE FALSE 2164.823784 2505.754939 2333.490685 2016.820259 1712.335107 2126.27778 1458.196487 621.4564326 2368.827867 2293.626685 0.943843128 1.092485955 1.017380335 0.879314961 0.746562254 0.927037427 0.635760168 0.270949251 1.032787019 1 11.16341488 -4.299112218 0.989588175 0.974604133 4.12E-24 0.864844957 0.086218887 0.480336707 0.373549184 0.01319702 0.489523371 5.02E-05 4.299112218 -0.974604133 down NSVEVALNK ddPTM_HeLa_Curcumin_4h_R1 1 NSVEVALNK 9 0 P54577;A0A0C4DGZ5 P54577 YARS "Tyrosine--tRNA ligase, cytoplasmic;Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed;Tyrosine--tRNA ligase" 0 0 98.044 0.011855 1725700 1438.9 1123.5 1150.5 1480.7 1356.4 1979 1057.4 1293.8 1753.6 1335.7 FALSE FALSE TRUE 1325.009547 1220.610334 1193.138542 1474.573256 1340.225816 1568.533092 1087.067798 1688.273664 1561.234467 1382.115476 0.95868223 0.88314642 0.863269794 1.066895843 0.969691635 1.134878467 0.786524583 1.221514189 1.129597704 1 10.43266244 -6.202216876 24.99826892 0.963151181 1.02386713 0.065618895 0.125684194 575.7554216 243030.3291 0.015734902 0.026093376 6.28E-07 6.202216876 0.060715949 NSVLSDPGLDS(ph)PRT(ph)SPVIMAR ddPTM_HeLa_Curcumin_4h_R1 2 NSVLSDPGLDSPRTSPVIMAR 21 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 2 0 NSVLSDPGLDS(0.667)PRT(0.667)S(0.667)PVIMAR;NS(0.002)VLS(0.034)DPGLDS(0.952)PRT(0.636)S(0.376)PVIMAR ; 67.579 0.0058701 48917000 2133.5 1450.12 1941.33 2084.97 2008.63 1838.85 1297.87 1076.62 2104.62 2092.73 TRUE FALSE FALSE 1964.631224 1575.461911 2013.277398 2076.342947 1984.678399 1457.451782 1334.284739 1404.876482 1873.748451 2165.452212 0.907261409 0.727544068 0.929726081 0.958849581 0.91651914 0.673047308 0.616169099 0.648768176 0.865291989 1 11.08045262 -3.321359894 0.309726586 0.972732609 1.13E-15 0.546872351 0.091192249 6.017967639 0.266417939 0.03586972 2.472614978 0.000477134 3.321359894 -0.972732609 NSVLSDPGLDS(ph)PRTS(ph)PVIMAR ddPTM_HeLa_Curcumin_4h_R1 1 NSVLSDPGLDSPRTSPVIMAR 21 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 2 0 NSVLS(0.002)DPGLDS(0.987)PRT(0.204)S(0.807)PVIMAR 67.312 0.0068244 25672000 974.61 738.66 1032 1053.9 1265.3 1275.7 816.59 481.24 1206.3 1061.2 TRUE FALSE FALSE 897.4685901 802.506479 1070.246828 1049.539241 1250.212124 1011.10544 839.5013177 627.9678606 1073.971908 1098.076621 0.817309624 0.730829219 0.974655873 0.95579782 1.138547256 0.920796801 0.764519799 0.57187982 0.978048241 1 10.10076301 -1.000000014 0.025938864 1.50196385 1.07E-05 0.154339701 0.142881628 3312.225607 6.671039627 131.7095592 281.1849623 0.099999997 1.000000014 -1.501953174 NSVSQISVLSGGK ddPTM_HeLa_Curcumin_4h_R1 2 NSVSQISVLSGGK 13 0 O15143 O15143 ARPC1B Actin-related protein 2/3 complex subunit 1B 0 0 ; ; 222.94 3.29E-28 4719000 3264.1 2190.8 2490.4 2656.7 2619.6 3060.4 2789.3 2393.5 2911.7 2849.5 FALSE FALSE TRUE 3005.743041 2380.16299 2582.696415 2645.707279 2588.362981 2425.638542 2867.560251 3123.267132 2592.293795 2948.519913 1.019407408 0.807239924 0.875929785 0.897300123 0.87785162 0.822663103 0.972542271 1.059266081 0.879184768 1 11.52577522 -7.295252782 24.78591304 1.00916462 0.899410206 0.046935248 0.079619034 454.7730853 333356.7586 0.011831581 0.013530344 5.07E-08 7.295252782 -0.109754414 NSYATTENKT(ph)LPR ddPTM_HeLa_Curcumin_4h_R1 1 NSYATTENKTLPR 13 1 B4DWA1;I3L4C2;Q9UQB8-3;Q9UQB8-5;Q9UQB8-4;Q9UQB8-2;Q9UQB8;I3L0Y9 B4DWA1 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 0 NSYAT(0.002)T(0.035)ENKT(0.963)LPR 96.435 0.0072626 32799000 2638.9 2500.5 2944.8 2869.4 2773.3 3766.6 3100.2 3424.5 2856.4 3235.3 TRUE FALSE FALSE 2430.02828 2716.632078 3053.936879 2857.527183 2740.230209 2985.364702 3187.183268 4468.614286 2543.060066 3347.726434 0.72587421 0.811485685 0.912242066 0.853572488 0.818534687 0.891758858 0.95204412 1.334820623 0.759637956 1 11.70896592 -4.189863599 2.113448801 0.862540344 1.524321178 0.791207891 0.074843543 0.409206017 1.711049907 0.014455205 0.54712226 6.46E-05 4.189863599 0.661780834 NSYLEVLLK ddPTM_HeLa_Curcumin_4h_R1 1 NSYLEVLLK 9 0 Q15084-3;Q15084;Q15084-4;Q15084-5;Q15084-2 Q15084-3 PDIA6 Protein disulfide-isomerase A6 0 0 110.14 0.0035773 491470 114.07 195.91 171.07 216.4 97.247 91.34 81.85 134.78 0 113.06 FALSE FALSE TRUE 105.0412391 212.8435874 177.4100047 215.5045941 96.08739304 72.39505439 84.14649071 175.8738015 0 116.9888266 0.897874115 1.819349708 1.516469648 1.842095527 0.821338207 0.618820245 0.719269465 1.503338453 0 1 6.870226937 NSYNNSQAPS(ph)PGLGSK ddPTM_HeLa_Curcumin_4h_R1 4 NSYNNSQAPSPGLGSK 16 0 Q9UHB7 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 0 NSYNNSQAPS(0.974)PGLGS(0.026)K;NSYNNS(0.066)QAPS(0.93)PGLGS(0.004)K;NSYNNSQAPS(1)PGLGSK;NSYNNS(0.001)QAPS(0.999)PGLGSK ;;; 211.26 4.74E-11 61397900 19575.2 15761.2 16877.8 17559.2 17305.3 22329.3 14991.7 13516.9 19750.6 18260.9 TRUE FALSE FALSE 18025.80226 17123.5279 17503.30612 17486.54468 17098.9456 17697.95148 15412.32675 17638.14059 17584.00859 18895.46492 0.953975059 0.906224217 0.926323125 0.925436064 0.904923254 0.936624293 0.815662744 0.933458937 0.930594123 1 14.2057524 -7.448289907 0.265197383 1.0187633 0.86994202 0.216032531 0.038985164 0.824579004 0.213914558 0.045881798 0.043784411 3.56E-08 7.448289907 -0.148821281 NSYVAGQYDDAASYQR ddPTM_HeLa_Curcumin_4h_R1 3 NSYVAGQYDDAASYQR 16 0 P11413;P11413-3;P11413-2;E9PD92;E7EM57;E7EUI8 P11413 G6PD Glucose-6-phosphate 1-dehydrogenase 0 0 ;; ;; 321.34 1.64E-111 21081500 4470.74 3488.07 4324.2 3888.85 3549.54 5119.2 3527.71 3271.37 4374.83 4261.2 FALSE FALSE TRUE 4116.876211 3789.563228 4484.458656 3872.758969 3507.214054 4057.420215 3626.688048 4268.795653 3894.922094 4409.276383 0.933685225 0.859452413 1.017050932 0.878320757 0.79541715 0.920200927 0.822513205 0.968139732 0.883347233 1 12.1063262 -7.991542006 0.392338834 1.007463172 0.875669803 0 0.070767776 0.979640659 0.387532559 0.052205899 0.03027697 1.02E-08 7.991542006 -0.131793369 NTAELQPESGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 NTAELQPESGKR 12 1 O15355 O15355 PPM1G Protein phosphatase 1G 0 1 ; NTAELQPESGK(1)R;NTAELQPESGK(1)R 237.76 5.73E-40 12128400 3457.8 3501.2 3270.9 2782.9 3256.3 3742.4 2978.4 3927.7 3918 3143.8 FALSE TRUE FALSE 3184.111481 3803.828127 3392.122431 2771.385097 3217.470749 2966.184054 3061.965888 5125.237649 3488.205202 3253.046816 0.978808994 1.169312445 1.042752417 0.851935202 0.98906377 0.911817205 0.941260935 1.575519179 1.072288657 1 11.66757587 -4.258642268 24.96533277 0.988364477 1.575519395 0.812876579 0.083463677 74.58322702 665647.2901 0.010873201 0.101026116 5.51E-05 4.258642268 0.587154917 NTASLNS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 NTASLNSR 8 0 C9JXI9;C9JSG7;C9JJM9;C9JD81;C9J3W7;C9JBN7;C9JEW7;C9J718;C9JF32;A0A0C4DG23;A0A3B3ITR4;O00522-3;O00522 C9JXI9 KRIT1 Krev interaction trapped protein 1 1 0 NT(0.001)AS(0.284)LNS(0.715)R 95.483 0.017697 50145000 2826.7 1998.3 2350 2566.5 2204.2 2867.4 1628.7 1254.1 2449.4 2323.9 TRUE FALSE FALSE 2602.963712 2171.024148 2437.093067 2555.880503 2177.916355 2272.668918 1674.396939 1636.469317 2180.706948 2404.655352 1.082468517 0.902842125 1.013489549 1.062888493 0.905708318 0.94511212 0.696314728 0.680542147 0.906868814 1 11.23161442 -4.783357124 1.105133592 1.027727549 0.607474734 0.710036558 0.070339275 0.245389629 0.406059445 0.009297027 0.096488415 1.65E-05 4.783357124 -0.420252815 NTASQNS(ph)ILEEGETK ddPTM_HeLa_Curcumin_4h_R1 1 NTASQNSILEEGETK 15 0 Q15398-1;Q15398-3;Q15398 Q15398-1 DLGAP5 Disks large-associated protein 5 1 0 NTASQNS(1)ILEEGETK 201.18 5.13E-31 0 9810.6 7822.6 8487 8512.8 8734.8 11896 8540.8 7904.6 10449 8589.2 TRUE FALSE FALSE 9034.080658 8498.750687 8801.535686 8477.576289 8630.643215 9428.635504 8780.431862 10314.67615 9302.770842 8887.674061 1.016472994 0.95624014 0.990308108 0.953857695 0.971080077 1.060866481 0.987933604 1.160559679 1.046704771 1 13.11759019 NTDDDRPPRR ddPTM_HeLa_Curcumin_4h_R1 3 NTDDDRPPRR 10 2 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 ;; ;; 72.321 0.015924 3308020 905.78 1481.79 987.59 600.38 543.34 890.93 582.47 484.403 856.04 1112.73 FALSE FALSE TRUE 834.0865572 1609.869325 1024.190954 597.8957866 536.8610254 706.1410751 598.8125406 632.0952448 762.1345537 1151.397285 0.724412475 1.398187529 0.889520036 0.519278441 0.466269143 0.613290551 0.520074651 0.54898101 0.661921444 1 10.16917 -6.275195525 7.29729875 0.916235872 0.533194556 0.531887112 0.187837445 0.104072842 33.41269299 0.028968869 0.045420552 5.31E-07 6.275195525 -0.383041316 NTDQASMPDNTAAQK ddPTM_HeLa_Curcumin_4h_R1 5 NTDQASMPDNTAAQK 15 0 P35579;P35579-2;A0A494C024;P35749-4;P35749-3;P35749;P35749-2 P35579;P35749-4 MYH9;MYH11 Myosin-9;Myosin-11 0 0 ;;;; ;;;; 279.65 2.60E-93 28320680 7802.22 6650.14 7169.36 8104.43 7053.78 9343.61 7345.87 6923.36 8703.2 8064.73 FALSE FALSE TRUE 7184.666054 7224.948469 7435.062788 8070.896016 6969.66828 7405.639962 7551.975342 9034.260593 7748.480734 8344.978767 0.860956781 0.865783925 0.890962457 0.967155968 0.835193051 0.887436645 0.904972385 1.082598392 0.928520126 1 13.02669266 -9.484286017 1.248655015 0.999581223 0.90291075 0.035985229 0.069997866 0.545413723 1.531909409 0.044407963 0.011052294 3.28E-10 9.484286017 -0.096670473 NTDVAQS(ph)PEAPK ddPTM_HeLa_Curcumin_4h_R1 2 NTDVAQSPEAPK 12 0 A0A087WVV2;Q9P2E9-3;Q9P2E9;V9GY78 A0A087WVV2 RRBP1 Ribosome-binding protein 1 1 0 NTDVAQS(1)PEAPK;NTDVAQS(1)PEAPK ; 191.01 5.33E-06 44363000 6632.9 5468.8 6332.5 6760.6 7540.5 8668.8 5819.2 2780.9 6420.9 4829.4 TRUE FALSE FALSE 6107.898966 5941.498704 6567.188021 6732.626429 7450.584462 6870.793162 5982.47109 3628.783608 5716.543334 4997.221291 1.222259054 1.188960496 1.314167942 1.347274022 1.490945473 1.374922735 1.19715953 0.726160279 1.143944405 1 12.28691039 -8.818541307 0.699987158 0.999207544 1.253557019 0.07620643 0.196566904 0.961039929 0.886207135 0.131027605 0.043803348 1.52E-09 8.818541307 0.254349475 NTDVAQS(ph)PEAPKQEAPAK ddPTM_HeLa_Curcumin_4h_R1 3 NTDVAQSPEAPKQEAPAK 18 1 A0A087WVV2;Q9P2E9-3;Q9P2E9;V9GY78 A0A087WVV2 RRBP1 Ribosome-binding protein 1 1 0 NT(0.019)DVAQS(0.981)PEAPKQEAPAK;NT(0.001)DVAQS(0.999)PEAPKQEAPAK;NTDVAQS(1)PEAPKQEAPAK ;; 119.94 0.00016083 233167000 17470.6 12598.3 14539 17035.9 15685.3 19950.3 13354.9 7906.3 18677.5 14086.2 TRUE FALSE FALSE 16087.78358 13687.24092 15077.82813 16965.40996 15498.26304 15812.38289 13729.60255 10316.89447 16628.62498 14575.6944 1.103740455 0.939045547 1.034450072 1.16395209 1.063295004 1.08484594 0.941951867 0.707814955 1.140846159 1 13.831277 -4.336534688 2.521253557 1.052098081 0.662884203 0.743445785 0.063887009 0.162089345 1.435766717 0.008822159 0.124368759 4.61E-05 4.336534688 -0.389213878 NTEDLQCYVK(ac)PTK ddPTM_HeLa_Curcumin_4h_R1 2 NTEDLQCYVKPTK 13 1 Q92613 Q92613 JADE3 Protein Jade-3 0 1 ; NTEDLQCYVK(1)PTK;NTEDLQCYVK(1)PTK 211.77 2.72E-20 3679300 1469.24 1017.1 1199.78 1214.41 1205.68 1627.72 1058.28 725.46 1123.38 1228.8 FALSE TRUE FALSE 1352.948104 1105.013592 1244.244902 1209.385093 1191.303053 1290.112524 1087.972489 946.6494144 1000.148025 1271.500709 1.064056115 0.869062506 0.978564065 0.951147793 0.936926771 1.014637676 0.855660151 0.744513478 0.786588649 1 10.31231655 -3.016359248 0.496296991 1.016604537 4.31E-27 0.104426674 0.092782167 6.173658726 0.406434748 0.012602761 4.848071733 0.000963032 3.016359248 -1.016604537 NTEDLTEEWLR ddPTM_HeLa_Curcumin_4h_R1 2 NTEDLTEEWLR 11 0 G3V4P8;P60983 G3V4P8 GMFB Glia maturation factor beta 0 0 ; ; 181.31 0.0011814 13164500 2402.5 2211.7 2422.3 2282.3 2125.39 2701.64 2082.27 2423.5 2347.7 2020.32 FALSE FALSE TRUE 2212.33959 2402.869493 2512.072569 2272.856447 2100.046112 2141.28941 2140.692892 3162.413994 2090.163184 2090.52597 1.058269365 1.149409062 1.201646191 1.087217514 1.004553946 1.024282617 1.023997273 1.512736048 0.999826462 1 11.02965025 -4.259491935 24.9073652 1.049821292 1.512736214 0.810082908 0.065412735 55.91855599 715127.2309 0.010079925 0.0874288 5.50E-05 4.259491935 0.462914922 NTEEEGLK(ac)YK ddPTM_HeLa_Curcumin_4h_R1 2 NTEEEGLKYK 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 1 ; NTEEEGLK(1)YK;NTEEEGLK(1)YK 152.54 3.55E-07 3874700 1653.65 1725.42 1447.07 1307.61 1751.24 2582.5 1515.9 1762.29 2624.7 1437.85 FALSE TRUE FALSE 1522.761858 1874.557616 1500.699687 1302.199456 1730.357607 2046.860389 1558.432074 2299.604108 2336.776977 1487.81518 1.023488588 1.259939837 1.008660018 0.875242754 1.16301919 1.375749096 1.047463485 1.545624845 1.570609715 1 10.53897961 -1 0.4583789 1.018244224 11.79571962 0.054927527 0.223269037 48.16126904 0.510532408 0.028226006 492.3203428 0.1 1 10.77747539 NTEESSS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 1 NTEESSSPVR 10 0 Q5T200-2;Q5T200;Q5T9K0 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 0 NT(0.003)EES(0.027)S(0.195)S(0.776)PVR 96.866 0.014657 11764000 4371.7 4464.9 5061.6 4279.9 4136.6 5514.8 3867.9 3084.4 4765.5 4395.7 TRUE FALSE FALSE 4025.675332 4850.826061 5249.187349 4262.190908 4087.273747 4370.968315 3976.422864 4024.819361 4242.736573 4548.450248 0.885065267 1.066478866 1.154060628 0.937064423 0.898607993 0.960979691 0.87423686 0.884877077 0.932787288 1 12.15115936 -5.039628904 1.266220196 0.968920159 0.876709755 0.204310561 0.076860557 0.950341437 2.55949823 0.01355512 0.078221467 9.13E-06 5.039628904 -0.092210405 NTENCDFLFS(ph)PPEVTGR ddPTM_HeLa_Curcumin_4h_R1 1 NTENCDFLFSPPEVTGR 17 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91;Q8IX09;C9JWI7;F8WC55 A0A494BZT8 TACC3;ERIC-1s Transforming acidic coiled-coil-containing protein 3 1 0 NTENCDFLFS(1)PPEVTGR 196.65 8.07E-08 9490800 2111.3 1764 1738.1 2043.2 2546.9 3144.5 2449.4 1101.3 1851.6 1764.3 TRUE FALSE FALSE 1944.188377 1916.4723 1802.515515 2034.74578 2516.529881 2492.295254 2518.123572 1437.0813 1648.484112 1825.609294 1.064953155 1.049771332 0.987350098 1.114557089 1.378460271 1.365185455 1.379333234 0.787179001 0.902977498 1 10.83416233 -5.975253318 8.065852808 1.031069371 1.248480233 0.277279297 0.167699791 0.192584881 51.09916246 0.022688053 0.040934779 1.06E-06 5.975253318 0.217410862 NTETQPTS(ph)PQLGTK ddPTM_HeLa_Curcumin_4h_R1 1 NTETQPTSPQLGTK 14 0 O95696-2 O95696-2 BRD1 Bromodomain-containing protein 1 1 0 NTETQPT(0.219)S(0.78)PQLGTK 116.58 0.0020741 16782000 6343 4850.2 5543 5638.4 5477.6 7456.6 5440 5142 6783.2 5878.7 TRUE FALSE FALSE 5840.944857 5269.429676 5748.428456 5615.069795 5412.283198 5910.017107 5592.631759 6709.772129 6039.099931 6082.984387 0.960210398 0.866257307 0.94500135 0.92307812 0.889741425 0.971565391 0.919389465 1.103039512 0.992785703 1 12.57056359 -8.272529748 1.263920409 0.992054214 0.942498313 0.089751349 0.060451176 0.632151195 2.059577863 0.015643281 0.011448115 5.34E-09 8.272529748 -0.0495559 NTFTAWS(ph)DEES(ph)DYEIDDRDVNK ddPTM_HeLa_Curcumin_4h_R1 1 NTFTAWSDEESDYEIDDRDVNK 22 1 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50 Q6PKG0 LARP1 La-related protein 1 2 0 NTFT(0.002)AWS(0.994)DEES(0.769)DY(0.235)EIDDRDVNK 89.353 0.00027771 170700000 3483.7 3972.3 3411.4 3791.7 3136 4031.7 3281.1 3729.8 3578.9 3453.2 TRUE FALSE FALSE 3207.961469 4315.647912 3537.829485 3776.01095 3098.605248 3195.479973 3373.158835 4866.99885 3186.303624 3573.198443 0.897784302 1.207782882 0.990101597 1.056759374 0.867179726 0.894291214 0.944016653 1.362084678 0.891723109 1 11.80300032 -4.259345522 24.8388251 0.96761044 1.362084826 0.592841965 0.096870303 90.82881533 1077390.992 0.013287157 0.116962019 5.50E-05 4.259345522 0.394474386 NTFTAWS(ph)DEESDYEIDDR ddPTM_HeLa_Curcumin_4h_R1 2 NTFTAWSDEESDYEIDDR 18 0 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 0 NTFT(0.371)AWS(0.629)DEESDYEIDDR;NTFT(0.007)AWS(0.981)DEES(0.011)DYEIDDR ; 170.22 1.01E-05 37689000 3077.9 3017.9 3338.2 2853.5 3855.1 3558.1 2843.4 2442.2 2876.4 3030.9 TRUE FALSE FALSE 2834.280967 3278.753828 3461.916629 2841.692973 3809.13045 2820.109952 2923.178151 3186.815537 2560.866116 3136.223549 0.903724152 1.045446467 1.103848809 0.906087506 1.21455961 0.899205655 0.932069448 1.016131499 0.816544508 1 11.61481268 -7.248827642 24.71844179 0.954536404 1.015685307 0.150833182 0.102211108 1281.981167 2512627.938 0.015246356 0.018600323 5.64E-08 7.248827642 0.061148903 NTFTAWS(ph)DEESDYEIDDRDVNK ddPTM_HeLa_Curcumin_4h_R1 6 NTFTAWSDEESDYEIDDRDVNK 22 1 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 0 NT(0.002)FT(0.062)AWS(0.576)DEES(0.05)DY(0.31)EIDDRDVNK;NT(0.003)FT(0.095)AWS(0.888)DEES(0.004)DY(0.009)EIDDRDVNK;NT(0.26)FT(0.189)AWS(0.546)DEES(0.004)DY(0.001)EIDDRDVNK;NT(0.013)FT(0.1)AWS(0.846)DEES(0.025)DY(0.017)EIDDRDVNK;NT(0.001)FT(0.05)AWS(0.948)DEES(0.001)DYEIDDRDVNK;NT(0.006)FT(0.06)AWS(0.932)DEES(0.002)DYEIDDRDVNK ;;;;; 120.92 3.85E-06 699720000 11081.71 10453 9690.48 10809.83 10096.09 11565.07 8682.46 8169.37 11627.31 10655.04 TRUE FALSE FALSE 10204.58096 11356.51074 10049.61771 10765.10179 9975.700721 9166.344117 8926.06646 10660.17331 10351.82318 11025.30185 0.925560234 1.030040801 0.911504996 0.976399734 0.90480069 0.83139167 0.809598375 0.966882672 0.938915172 1 13.42853053 -5.587276944 3.817037174 0.965669005 0.863434756 0.418039251 0.050438744 0.151675937 4.461498727 0.007329556 0.01553915 2.59E-06 5.587276944 -0.102234249 NTFTAWSDEESDY(ph)EIDDRDVNK ddPTM_HeLa_Curcumin_4h_R1 2 NTFTAWSDEESDYEIDDRDVNK 22 1 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50 Q6PKG0 LARP1 La-related protein 1 1 0 NT(0.001)FT(0.046)AWS(0.338)DEES(0.032)DY(0.583)EIDDRDVNK;NTFT(0.004)AWS(0.103)DEES(0.205)DY(0.687)EIDDRDVNK ; 103.41 0.00020707 33553100 2674.2 2602.9 2372.3 2897.4 2441.9 2424.1 1945.83 2084.7 2810.9 2800.1 TRUE FALSE FALSE 2462.534248 2827.883078 2460.219525 2885.411327 2412.781937 1921.314335 2000.424753 2720.315433 2502.551303 2897.403267 0.849910772 0.976006036 0.849111877 0.995861142 0.832739427 0.663115955 0.690419858 0.938880502 0.863722124 1 11.50054478 -5.538185588 6.868590782 0.928531169 0.755045435 0.403944159 0.086620267 0.103704329 22.32913126 0.012847156 0.026407171 2.90E-06 5.538185588 -0.173485733 NTGIICTIGPASR ddPTM_HeLa_Curcumin_4h_R1 2 NTGIICTIGPASR 13 0 P14618;B4DNK4;H3BU13;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 137.95 0.00073895 54468000 2805.29 2411.4 2675.29 2592.15 2674.67 2997.72 2707.26 2528.95 3077.18 2561.12 FALSE FALSE TRUE 2583.248336 2619.830671 2774.438601 2581.42437 2642.776307 2375.959081 2783.218429 3300.015213 2739.621053 2650.118729 0.97476702 0.988571056 1.046911057 0.974078762 0.997229399 0.896548164 1.050224052 1.245232969 1.033772948 1 11.37184128 -4.316378713 3.437147978 0.986524869 1.263697572 0.795026841 0.038907516 0.07175623 1.419290428 0.004705342 0.047099582 4.83E-05 4.316378713 0.277172703 NTGNGTQSSMGSPLT(ph)RPTPR ddPTM_HeLa_Curcumin_4h_R1 1 NTGNGTQSSMGSPLTRPTPR 20 1 E3W994;J3KR49;O75122;E7ERI8;E7EW49;O75122-3;A0A0U1RQI6;H7C4I5 E3W994 CLASP2 CLIP-associating protein 2 1 0 NTGNGT(0.001)QS(0.031)S(0.341)MGS(0.009)PLT(0.447)RPT(0.172)PR 59.182 0.010179 6428700 1280.8 876.91 1117.6 1300.6 1178.5 1791.7 1416.3 597.73 1366.4 1112.7 TRUE FALSE FALSE 1179.423329 952.706193 1159.019239 1295.218462 1164.447157 1420.081223 1456.037566 779.9751254 1216.509339 1151.366242 1.024368516 0.827457118 1.006646883 1.124940453 1.011361211 1.233387928 1.264617211 0.677434423 1.056578953 1 10.1691311 -6.376773251 7.092674082 0.994375414 1.080014173 0.050000957 0.160968656 0.589814663 32.80501943 0.023147442 0.035416422 4.20E-07 6.376773251 0.085638759 NTGVSPASRPSPGTPT(ph)SPSNLTSGLK ddPTM_HeLa_Curcumin_4h_R1 1 NTGVSPASRPSPGTPTSPSNLTSGLK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 NTGVSPASRPSPGTPT(0.468)S(0.468)PS(0.059)NLT(0.004)S(0.001)GLK 94.389 7.42E-06 120330000 1738.7 1593 1588.6 1221.2 1596.2 2117.2 1360 1047.4 1727.7 1585.9 TRUE FALSE FALSE 1601.08006 1730.691822 1647.474913 1216.146998 1577.166358 1678.068854 1398.15794 1366.747438 1538.175632 1641.009907 0.975667516 1.054650441 1.003939651 0.741096682 0.961094964 1.022583013 0.852010664 0.832869706 0.937334763 1 10.68036823 NTGVSPASRPSPGTPTS(ph)PSNLTSGLK ddPTM_HeLa_Curcumin_4h_R1 1 NTGVSPASRPSPGTPTSPSNLTSGLK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 NTGVSPASRPSPGTPT(0.066)S(0.915)PS(0.016)NLT(0.002)S(0.001)GLK 106.33 9.14E-08 128980000 1964.4 1426 1409 1645.2 2075.3 1936.2 1344.5 1195.8 2317.6 1756.9 TRUE FALSE FALSE 1808.915667 1549.257086 1461.218779 1638.392598 2050.553403 1534.610295 1382.223051 1560.393915 2063.365078 1817.952144 0.99502931 0.852199048 0.803771862 0.901229773 1.127946855 0.844142295 0.760318722 0.858325078 1.134994166 1 10.82809851 -1.000000008 0.148837707 1.0379261 0.223733914 0.307589422 0.103396626 70.88316355 0.683959446 0.226188174 12.4920987 0.099999998 1.000000008 -0.814192186 NTLDSEVPAAYQT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 NTLDSEVPAAYQTPK 15 0 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 0 NTLDSEVPAAYQT(1)PK;NTLDSEVPAAY(0.001)QT(0.999)PK ; 145.82 0.0014036 16116700 6665.5 5220.3 6567.4 6235.6 6050.8 5929.4 4696.8 2330.5 6522.1 5864.3 TRUE FALSE FALSE 6137.918642 5671.519471 6810.793621 6209.798739 5978.648162 4699.575602 4828.579567 3041.058722 5806.641947 6068.083989 1.011508518 0.93464749 1.12239607 1.023354118 0.985261274 0.774474383 0.795733806 0.501156333 0.956915224 1 12.56702534 -4.25645796 0.870814888 1.01168557 0.237236694 0.860881521 0.062791614 0.531279576 0.292722124 0.009156065 0.393358584 5.54E-05 4.25645796 -0.774448875 NTLPTKETIEQEK ddPTM_HeLa_Curcumin_4h_R1 2 NTLPTKETIEQEK 13 1 P63313;CON__P21752 P63313 TMSB10 Thymosin beta-10 0 0 ; ; 115.34 5.96E-05 2992000 4078.9 2925.5 3274.3 3754.2 2730.5 3883.5 3125.2 2760.7 4907.4 4747.6 FALSE FALSE TRUE 3756.050761 3178.367184 3395.648438 3738.666115 2697.940571 3078.018324 3212.884701 3602.424721 4369.070498 4912.578747 0.76457823 0.646985493 0.691215065 0.761039427 0.549190295 0.626558572 0.654011847 0.733306255 0.889363962 1 12.26226482 -8.481246686 0.479869741 1.0232924 0.64664249 0.730329303 0.06527533 0.304724222 0.143948506 0.051311423 0.019119271 3.30E-09 8.481246686 -0.376649909 NTLPTKETIEQEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 NTLPTKETIEQEKR 14 2 P63313 P63313 TMSB10 Thymosin beta-10 0 1 ; NTLPTKETIEQEK(1)R;NTLPTKETIEQEK(1)R 130.61 0.00040118 33476000 3898.9 4300.9 2922.5 3097.7 4633 7858 4932.8 5968.7 10623.8 4357.6 FALSE TRUE FALSE 3590.297951 4672.650632 3030.810421 3084.882538 4577.754501 6228.162222 5071.201092 7788.529153 9458.395719 4509.026276 0.796246846 1.03628818 0.672165172 0.684157144 1.015242365 1.381265453 1.124677654 1.727319531 2.097658151 1 12.1386002 -5.336428094 3.23727987 0.878502738 1.391684458 0.057377142 0.424248258 0.124368381 2.532361721 0.025594696 0.063813721 4.61E-06 5.336428094 0.51318172 NTLPTKETIEQEKR ddPTM_HeLa_Curcumin_4h_R1 1 NTLPTKETIEQEKR 14 2 P63313 P63313 TMSB10 Thymosin beta-10 0 0 68.033 0.01347 15378000 3569.1 2771.3 2749.7 2937 1815.8 3206.4 2598.3 2569.5 4229.8 3507.3 FALSE FALSE TRUE 3286.601969 3010.838823 2851.606301 2924.847472 1794.147771 2541.356496 2671.201305 3352.928721 3765.801522 3629.178414 0.905604959 0.829619952 0.785744313 0.805925512 0.494367476 0.700256699 0.736034717 0.923880928 1.03764574 1 11.82542727 -7.159639321 0.905606663 0.972452531 0.718884447 0.530035045 0.103228282 0.303633917 0.495268353 0.023079835 0.029055982 6.92E-08 7.159639321 -0.253568084 S(ph)GAQASST(ph)PLSPTR ddPTM_HeLa_Curcumin_4h_R1 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 S(1)GAQAS(0.124)S(0.253)T(0.618)PLS(0.005)PTR 172.56 0.00088595 35875000 2341.7 2411.6 1964.2 2560.2 2587.8 3777.6 2047.5 516.37 3318.1 2651.9 TRUE FALSE FALSE 2156.351974 2620.047958 2036.99498 2549.606571 2556.942175 2994.083178 2104.947339 673.8088359 2954.112731 2744.053328 0.785827284 0.954809417 0.742330683 0.929138856 0.93181213 1.091116979 0.767094181 0.245552384 1.076550773 1 11.4220928 -4.298431817 3.462258071 0.905086797 0.188647401 0.779763923 0.109435528 0.091066933 1.869579928 0.014887666 0.160666691 5.03E-05 4.298431817 -0.716439396 down NTPS(ph)PDVTLGTNPGTEDIQFPIQK ddPTM_HeLa_Curcumin_4h_R1 2 NTPSPDVTLGTNPGTEDIQFPIQK 24 0 M0R3F6;M0R2Z9;Q8IX01-4;Q8IX01-3;Q8IX01 M0R3F6 SUGP2 SURP and G-patch domain-containing protein 2 1 0 NT(0.152)PS(0.813)PDVT(0.035)LGTNPGTEDIQFPIQK;NT(0.079)PS(0.815)PDVT(0.105)LGT(0.001)NPGTEDIQFPIQK ; 106.6 1.75E-06 9784900 7219.1 5755.7 6447.1 6914.6 6342.6 8238.5 7917.5 8051.6 7305.8 6213.2 TRUE FALSE FALSE 6647.700617 6253.197061 6686.035197 6885.989217 6266.968637 6529.742233 8139.643741 10506.49577 6504.372018 6429.108238 1.03400042 0.972638324 1.039963079 1.07106444 0.97478039 1.01565287 1.266061083 1.634207325 1.011706722 1 12.65040292 -4.376514616 2.038326546 1.014995431 1.731413843 0.974978759 0.030775143 0.058496303 0.313889665 0.004476074 0.070594048 4.20E-05 4.376514616 0.716418412 NTPSQHSHS(ph)IQHSPER ddPTM_HeLa_Curcumin_4h_R1 1 NTPSQHSHSIQHSPER 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 NTPSQHS(0.398)HS(0.573)IQHS(0.028)PER 70.114 0.011807 1271500 0 81.595 161.21 0 0 82.192 0 0 0 0 TRUE FALSE FALSE 0 88.64770822 167.1845844 0 0 65.14445271 0 0 0 0 0 NTPSQHSHSIQHS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 NTPSQHSHSIQHSPER 16 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 NTPSQHS(0.008)HS(0.234)IQHS(0.758)PER 78.554 0.0048912 23536000 1624 1353.7 1208.2 966.31 2072.3 4452.3 1678.6 1893.5 2629.1 1385.6 TRUE FALSE FALSE 1495.458686 1470.707796 1252.976955 962.3116653 2047.589176 3528.842792 1725.696998 2470.819433 2340.694308 1433.749497 1.043040426 1.025777376 0.87391623 0.671185355 1.428135933 2.461268722 1.203625181 1.723327149 1.632568529 1 10.48557726 -5.531125853 13.00396495 0.989687602 1.771472463 0.460732615 0.365100815 0.286478501 449.1349584 0.040752997 0.082398243 2.94E-06 5.531125853 0.781784861 TYS(ph)SPGSFK ddPTM_HeLa_Curcumin_4h_R1 1 TYSSPGSFK 9 0 Q8N3Z6 Q8N3Z6 ZCCHC7 Zinc finger CCHC domain-containing protein 7 1 0 T(0.022)YS(0.489)S(0.489)PGSFK 131.52 0.0036805 29096000 13761 12053 12526 13489 12305 16882 10547 4384.8 14766 12317 TRUE FALSE FALSE 12671.80233 13094.80761 12990.22458 13433.18609 12158.27091 13380.4829 10842.92043 5721.705335 13146.20674 12745.01483 0.994255597 1.027445459 1.01923966 1.053995328 0.953962869 1.049860128 0.850757773 0.448936734 1.03147834 1 13.63764543 -4.298237913 2.460371655 1.004724301 0.349018748 0.967312867 0.031476884 0.051129204 0.401975219 0.003911522 0.067802042 5.03E-05 4.298237913 -0.655705553 down NTS(ph)PSLGESR ddPTM_HeLa_Curcumin_4h_R1 1 NTSPSLGESR 10 0 C9J052;Q9NSU2-2;Q9NSU2;Q9NSU2-1 C9J052 TREX1 Three-prime repair exonuclease 1 1 0 NT(0.066)S(0.867)PS(0.066)LGESR 107.39 0.0087318 17983000 4455.4 3371.2 4269.4 4301.7 4119.4 3525.4 2369.4 1795.4 4318.3 3473.9 TRUE FALSE FALSE 4102.750389 3662.591506 4427.62772 4283.900705 4070.278845 2794.192301 2435.878987 2342.809195 3844.593294 3594.617766 1.141359292 1.018909866 1.231738117 1.191754168 1.132325913 0.777326682 0.677646177 0.651754748 1.069541616 1 11.81162265 -5.140246163 3.607066434 1.090631913 0.674817776 0.87577832 0.071084201 0.074472208 1.749104498 0.012445706 0.034816586 7.24E-06 5.140246163 -0.415814137 NTSAEKELSSPIS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 NTSAEKELSSPISPK 15 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 NTSAEKELS(0.019)S(0.063)PIS(0.918)PK 61.757 0.018896 12631000 4063.2 3450.2 3058.4 4090.6 2906.9 4018.1 2801.3 1697.3 5378.5 4201.6 TRUE FALSE FALSE 3741.593433 3748.419914 3171.746994 4073.674181 2872.237116 3184.700767 2879.896939 2214.798957 4788.492006 4347.605287 0.860610195 0.862180365 0.729538858 0.936992646 0.660648087 0.732518376 0.662409936 0.509429631 1.101409095 1 12.08600525 -3.356715788 0.190344651 1.018848901 1.35E-12 0.780280216 0.079706041 7.026000458 0.174026941 0.086714354 1.796429938 0.000439829 3.356715788 -1.018848901 NTSAS(ph)DEDER ddPTM_HeLa_Curcumin_4h_R1 1 NTSASDEDER 10 0 Q32MZ4-2;Q32MZ4;C9JTC6;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 0 NTS(0.007)AS(0.992)DEDER 107.53 0.0086705 1188000 543.77 1192.6 760.89 542.29 770.45 611.14 212.95 308.78 457.38 582.54 TRUE FALSE FALSE 500.7300307 1295.68303 789.0892527 540.0461477 761.2628869 484.382675 218.9248039 402.9256006 407.2065583 602.7832216 0.830696696 2.149500821 1.309076339 0.895921002 1.262913199 0.803576904 0.363189943 0.668441964 0.67554395 1 9.23549545 -4.990221511 5.24460386 1.060450422 0.523486184 0.282177824 0.396003092 0.191006656 16.22383023 0.057120108 0.169102873 1.02E-05 4.990221511 -0.536964238 NTSGLPAEPESVS(ph)SPPTLHMK ddPTM_HeLa_Curcumin_4h_R1 1 NTSGLPAEPESVSSPPTLHMK 21 0 Q8IWI9-3;Q8IWI9 Q8IWI9-3 MGA MAX gene-associated protein 1 0 NTSGLPAEPES(0.012)VS(0.818)S(0.17)PPT(0.001)LHMK 67.396 0.0023084 5500100 2132.9 1394.1 1506.6 2201.8 1531 2810.1 2303.9 1300.1 2582 1782.6 TRUE FALSE FALSE 1964.078714 1514.599792 1562.435921 2192.689535 1512.743825 2227.253584 2368.541233 1696.494505 2298.76106 1844.545217 1.064803777 0.821123699 0.847057533 1.188742631 0.820117507 1.207481152 1.284078705 0.919735927 1.246248147 1 10.84904944 -5.220069029 24.99962821 1.001048313 1.151796627 0.131447904 0.162077603 628.943104 380062.2859 0.01907099 0.048621098 6.02E-06 5.220069029 0.150748314 NTSLPPLWS(ph)PEAER ddPTM_HeLa_Curcumin_4h_R1 4 NTSLPPLWSPEAER 14 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 0 NTS(0.001)LPPLWS(0.999)PEAER;NTSLPPLWS(1)PEAER;NTSLPPLWS(1)PEAER;NT(0.017)S(0.008)LPPLWS(0.975)PEAER ;;; 152.68 0.00044888 195329000 15881.8 12791.9 13566.7 13697.4 13514.6 17389.6 14531.6 11074.7 15950.3 13575.2 TRUE FALSE FALSE 14624.73877 13897.57484 14069.49384 13640.72379 13353.44722 13782.80094 14939.31759 14451.32505 14200.592 14046.93719 1.041133635 0.98936691 1.001605805 0.97108171 0.950630521 0.981196168 1.063528468 1.02878833 1.01093867 1 13.77796798 -7.235352781 24.3966631 1.019424219 0.997178323 0.074637295 0.030831671 1124.988905 1052110.171 0.005831077 0.007139175 5.82E-08 7.235352781 -0.022245897 NTSPS(ph)LGESR ddPTM_HeLa_Curcumin_4h_R1 1 NTSPSLGESR 10 0 C9J052;Q9NSU2-2;Q9NSU2;Q9NSU2-1 C9J052 TREX1 Three-prime repair exonuclease 1 1 0 NT(0.037)S(0.118)PS(0.816)LGES(0.029)R 96.23 0.015079 16402000 4676.5 3063.6 3912.4 4553.7 4140.5 3441.8 2273.9 1383.1 4594.4 3937.2 TRUE FALSE FALSE 4306.35009 3328.403933 4057.396986 4534.857996 4091.127242 2727.931883 2337.699514 1804.800823 4090.405815 4074.017407 1.057027906 0.816983238 0.995920385 1.113116991 1.004199745 0.669592594 0.573806953 0.443002727 1.004022665 1 11.99223643 -5.090914797 2.280431917 1.015788658 0.501877072 0.873077372 0.077710371 0.075291132 0.754303202 0.011648235 0.039983439 8.11E-06 5.090914797 -0.513911586 NTSS(ph)NS(ph)S(ph)PLNLK ddPTM_HeLa_Curcumin_4h_R1 1 NTSSNSSPLNLK 12 0 A0A0A0MR69;Q9P219-3;Q9P219-2;Q9P219 A0A0A0MR69 CCDC88C Protein Daple 3 0 NT(0.138)S(0.43)S(0.518)NS(0.937)S(0.977)PLNLK 73.834 0.0080953 0 1017.6 954.87 883.57 1382.9 1178.1 1508 1260.5 972.26 1036.3 1208.4 TRUE FALSE FALSE 937.0558862 1037.404708 916.3158815 1377.177926 1164.051927 1195.223801 1295.866238 1268.697598 922.6204827 1250.39181 0.749409808 0.82966371 0.732823003 1.10139711 0.930949737 0.955879423 1.036368142 1.014640042 0.737865104 1 10.28816452 -6.25328783 24.94089898 0.863784099 1.002272254 0.497233912 0.091753637 623.8531676 1908771.845 0.016857545 0.027651518 5.58E-07 6.25328783 0.138488155 NTVVPTK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 NTVVPTKK 8 1 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 1 NTVVPTK(1)K 109.29 0.0023241 1901600 4235.1 7008.9 3454.6 3755.3 5715 7026.4 4953.2 3905.6 5699.8 3599 FALSE TRUE FALSE 3899.887366 7614.718085 3582.630515 3739.761564 5646.852358 5569.045436 5092.173461 5096.399461 5074.5462 3724.064982 1.047212491 2.044732872 0.962021482 1.004214905 1.516314131 1.495421123 1.367369658 1.368504439 1.362636319 1 11.86266253 -7.478716332 24.99969974 1.020828518 1.382607951 0.098216076 0.301128769 415.2458978 235066.2071 0.046571221 0.052933491 3.32E-08 7.478716332 0.361779433 TADSSSS(ph)EDEEEYVVEK ddPTM_HeLa_Curcumin_4h_R1 3 TADSSSSEDEEEYVVEK 17 0 P45973;F8VNY3 P45973 CBX5 Chromobox protein homolog 5 1 0 TADSSS(0.021)S(0.978)EDEEEYVVEK;TADSSS(0.017)S(0.983)EDEEEYVVEK;TADS(0.004)S(0.001)S(0.116)S(0.88)EDEEEYVVEK ;; 308 1.37E-95 240820000 10788.3 8578.3 8389.64 9663.23 9413.33 10808.71 6575.87 1605.47 10534.38 8475.58 TRUE FALSE FALSE 9934.394671 9319.770028 8700.567439 9623.246115 9301.082188 8566.861707 6760.371214 2094.970412 9378.78487 8770.105774 1.13275654 1.062674758 0.992070981 1.097278227 1.060543901 0.976825357 0.770842609 0.238876299 1.069403849 1 13.09837853 -4.297934501 1.639778735 1.060533008 2.86E-20 0.973866531 0.040771055 0.131610464 0.353495375 0.007893379 0.215474605 5.04E-05 4.297934501 -1.060533008 down NVALLSQLYHS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 2 NVALLSQLYHSPAR 14 0 Q15717;Q15717-2 Q15717 ELAVL1 ELAV-like protein 1 1 0 NVALLS(0.001)QLYHS(0.999)PAR;NVALLSQLYHS(1)PAR ; 166.9 0.00021187 175170000 2379.5 2139.28 1940.58 1771.79 2616.9 4486.2 3494.2 1592.49 2314.5 1527.52 TRUE FALSE FALSE 2191.160064 2324.189831 2012.499602 1764.458802 2585.695177 3555.71155 3592.237848 2078.03287 2060.605141 1580.601206 1.386282672 1.470446702 1.273249441 1.116321306 1.63589346 2.249594354 2.272703471 1.314710416 1.303684403 1 10.6262577 -5.561066389 4.141181057 1.21548574 1.977872408 0.551960142 0.27701057 0.109875308 4.131520875 0.041977931 0.089168991 2.75E-06 5.561066389 0.762386668 NVDNAEGS(ph)DTDY ddPTM_HeLa_Curcumin_4h_R1 2 NVDNAEGSDTDY 12 0 Q15751 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 0 NVDNAEGS(0.704)DT(0.296)DY;NVDNAEGS(0.998)DT(0.002)DY ; 124.12 0.0031442 23814000 7937.2 6125 6736 7226.4 6082.8 6653.9 5091.7 4468.2 6834.6 7477 TRUE FALSE FALSE 7308.962245 6654.417708 6985.642086 7196.499072 6010.266583 5273.806135 5234.559398 5830.533611 6084.861479 7736.825193 0.944697865 0.860096686 0.902908094 0.930161777 0.776838875 0.681649902 0.676577183 0.753608032 0.786480414 1 12.91752596 -5.793639846 0.540572459 0.982158334 0.65295535 0.471900621 0.077724954 0.344372016 0.163017755 0.011830605 0.054212533 1.61E-06 5.793639846 -0.329202984 LSPQDPRPLS(ph)PGALQLAGEK ddPTM_HeLa_Curcumin_4h_R1 1 LSPQDPRPLSPGALQLAGEK 20 1 Q8TEK3;Q8TEK3-1 Q8TEK3 DOT1L "Histone-lysine N-methyltransferase, H3 lysine-79 specific" 1 0 LS(0.004)PQDPRPLS(0.996)PGALQLAGEK 67.227 0.0033564 21153000 994.76 813.72 971.7 947.59 1110.5 1053.9 752.87 362.93 1164.9 1006.9 TRUE FALSE FALSE 916.0236963 884.0543309 1007.712057 943.6691237 1097.258013 835.3092601 773.993506 473.5856863 1037.113384 1041.8897 0.879194502 0.848510481 0.967196486 0.905728431 1.053142202 0.801725231 0.742874707 0.454544935 0.995415719 1 10.02498684 -4.297850838 1.317452394 0.93914848 0.270858861 0.842953798 0.065189305 0.37523996 0.581873723 0.010169366 0.32911925 5.04E-05 4.297850838 -0.668289619 down SSQLDSGVPSS(ph)PGGR ddPTM_HeLa_Curcumin_4h_R1 1 SSQLDSGVPSSPGGR 15 0 I3L4X5;Q70CQ4 I3L4X5 USP31 Ubiquitin carboxyl-terminal hydrolase 31 1 0 SSQLDS(0.006)GVPS(0.227)S(0.767)PGGR 180.56 5.55E-05 9667900 2455 2285 2572.4 3022.5 2607.2 2868.4 1833.7 685.07 3231.5 2500.8 TRUE FALSE FALSE 2260.684159 2482.505218 2667.735407 3009.993696 2576.110843 2273.461506 1885.148687 893.9446893 2877.012535 2587.702614 0.873625952 0.959347185 1.030928126 1.163191504 0.995520439 0.87856367 0.728502834 0.345458819 1.111801843 1 11.33745611 -4.297389233 1.563301328 0.966743981 0.140624557 0.843562229 0.087663686 0.305712871 0.726508367 0.013209542 0.37678605 5.04E-05 4.297389233 -0.826119425 down NVFHIASQK(ac)NFK ddPTM_HeLa_Curcumin_4h_R1 2 NVFHIASQKNFK 12 1 E5RGR5;A0A087WWE7;Q8N0T1-2;Q8N0T1 E5RGR5 C8orf59 Uncharacterized protein C8orf59 0 1 ; NVFHIASQK(1)NFK;NVFHIASQK(1)NFK 113.95 0.0026192 15238100 8735.1 7871 7903.9 7736 9332.4 12861.4 6136.7 4610.8 8630.9 7801.9 FALSE TRUE FALSE 8043.707618 8551.334168 8196.825487 7703.990482 9221.117225 10193.80066 6308.879286 6016.611694 7684.111863 8073.015444 0.996369656 1.059249078 1.015336282 0.95428908 1.142214739 1.262700503 0.781477421 0.745274394 0.951826727 1 12.97889194 -4.599403181 12.45515343 1.025111161 0.754321818 0.601600763 0.091295719 0.306408957 48.58593526 0.012544134 0.046963083 2.52E-05 4.599403181 -0.270789344 NVFSSSGTSFS(ph)GRK ddPTM_HeLa_Curcumin_4h_R1 1 NVFSSSGTSFSGRK 14 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 0 NVFSSS(0.179)GT(0.126)S(0.126)FS(0.568)GRK 107.74 0.005223 9224800 1438.6 1166.3 1033.8 999.73 1088.5 2113.6 1698.8 730.33 1546.5 1016.4 TRUE FALSE FALSE 1324.733292 1267.109775 1072.113537 995.5933822 1075.520348 1675.215535 1746.463756 953.004255 1376.852819 1051.719824 1.25958764 1.204797842 1.019390823 0.946633656 1.022630099 1.592834418 1.660578907 0.90613891 1.309144115 1 10.03853471 -13.52287711 0.040781123 2.12E-11 1.826033753 0 0.255014136 1152.436928 3.749588903 147.5525854 46.91967697 3.00E-14 13.52287711 1.826033753 T(ph)DSLAATPPAAK ddPTM_HeLa_Curcumin_4h_R1 1 TDSLAATPPAAK 12 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 T(0.716)DS(0.028)LAAT(0.256)PPAAK 145.81 0.0024041 62321000 7346.4 5869.1 6396.3 6938.8 6610 7930.3 4789.9 1613.3 7541.7 5718.5 TRUE FALSE FALSE 6764.924688 6376.398852 6633.352505 6910.089084 6531.180067 6285.466387 4924.291703 2105.187743 6714.394378 5917.217449 1.143261127 1.0776009 1.121025644 1.16779367 1.103758671 1.062233464 0.832197185 0.35577326 1.134721588 1 12.5307032 -4.295398104 1.873898881 1.084444022 0.156107449 0.958658742 0.047480833 0.139584815 0.527049693 0.009079641 0.22008886 5.07E-05 4.295398104 -0.928336573 down NVHS(ph)EDFENR ddPTM_HeLa_Curcumin_4h_R1 2 NVHSEDFENR 10 0 Q9H2P0;A0A669KBJ7 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 1 0 NVHS(1)EDFENR;NVHS(1)EDFENR ; 120.29 0.0021342 111064000 8307.1 6379 7472.5 7935.2 7331.8 8944.3 6392.1 4012.8 8410.1 7087.1 TRUE FALSE FALSE 7649.584269 6930.372336 7749.437423 7902.366245 7244.373074 7089.151357 6571.445123 5236.284247 7487.533071 7333.376197 1.04311903 0.945045249 1.05673529 1.077589098 0.987863281 0.966696807 0.896100915 0.714034587 1.021021269 1 12.84026184 -4.095903902 1.1197274 1.020661955 0.476554748 0.877527951 0.034973842 0.547019263 0.433294393 0.005388962 0.380839603 8.02E-05 4.095903902 -0.544107207 NVIFQPVAELK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 NVIFQPVAELKK 12 1 Q01813;Q01813-2;B1APP6;H0Y757 Q01813 PFKP "ATP-dependent 6-phosphofructokinase, platelet type" 0 1 ; NVIFQPVAELK(1)K;NVIFQPVAELK(1)K 156.58 6.81E-06 1598270 1008.62 1333.03 1048.01 891.94 1361.63 2514.74 1686.05 1736.5 2088.92 1132.24 FALSE TRUE FALSE 928.7866627 1448.251173 1086.850173 888.2493886 1345.393452 1993.154577 1733.356025 2265.950856 1859.770702 1171.585256 0.792760628 1.236146637 0.927674847 0.758160266 1.148353007 1.701245869 1.479496278 1.934089598 1.587396814 1 10.19424623 -5.372185359 3.166096831 0.92092251 1.690988628 0.520214737 0.265171572 0.077293371 1.463654322 0.023527497 0.057791599 4.24E-06 5.372185359 0.770066118 NVIFQPVAELKK ddPTM_HeLa_Curcumin_4h_R1 2 NVIFQPVAELKK 12 1 Q01813;Q01813-2;B1APP6;H0Y757 Q01813 PFKP "ATP-dependent 6-phosphofructokinase, platelet type" 0 0 ; ; 158.34 4.70E-06 3093600 1897.32 1705.18 1709.62 1617.99 1218.81 2090.98 1802.25 1747.74 1853.32 2133.55 FALSE FALSE TRUE 1747.14512 1852.568161 1772.980021 1611.295186 1204.276487 1657.287178 1852.816284 2280.61788 1650.015433 2207.690704 0.791390351 0.839142982 0.803092579 0.729855493 0.545491488 0.750688117 0.839255373 1.03303324 0.747394293 1 11.10832235 -9.060928223 0.612259472 1.019759932 0.778018317 0 0.13778313 0.948111113 0.578392242 0.123354706 0.02795091 8.69E-10 9.060928223 -0.241741614 NVIGLQMGTNR ddPTM_HeLa_Curcumin_4h_R1 2 NVIGLQMGTNR 11 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 0 ; ; 119.22 0.0022046 9925000 3049.4 1939.58 2559.6 2220.94 2811.6 3035.4 2501.1 2138.34 2653.4 2547.5 FALSE FALSE TRUE 2808.036772 2107.228653 2654.461028 2211.750339 2778.073506 2405.823824 2571.274135 2790.310022 2362.328658 2636.025435 1.065254051 0.799396176 1.006993708 0.839047419 1.053887216 0.912670945 0.975436011 1.058529248 0.896170662 1 11.36414858 NVIPDT(ph)PPSTPLVPSR ddPTM_HeLa_Curcumin_4h_R1 1 NVIPDTPPSTPLVPSR 16 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 0 NVIPDT(0.551)PPS(0.15)T(0.041)PLVPS(0.258)R 100.58 0.0079974 10958000 2426.2 1748.4 1794.2 2286.5 1935.2 1757.8 1468.4 1525.2 2049.3 1572 TRUE FALSE FALSE 2234.16371 1899.523905 1860.69463 2277.039069 1912.124004 1393.212466 1509.599352 1990.226459 1824.496917 1626.626883 1.373494889 1.167768666 1.143897626 1.399853336 1.175514818 0.856504021 0.928055086 1.223529796 1.121644389 1 10.66766765 -5.390147376 8.109457308 1.194760217 0.995854495 0.288754898 0.140181105 0.335546181 20.51686607 0.02456723 0.055064892 4.07E-06 5.390147376 -0.198905722 NVLLLGEDGAGK ddPTM_HeLa_Curcumin_4h_R1 1 NVLLLGEDGAGK 12 0 Q9Y6G9 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 0 0 105.25 0.004982 1145900 970.47 775.31 920.6 940.38 685.03 1023.5 783.41 860.63 1047.5 893.36 FALSE FALSE TRUE 893.6562755 842.3243417 954.7182458 936.4889567 676.8614647 811.2145628 805.3903762 1123.032125 932.5918707 924.4041935 0.966737583 0.911207833 1.032793071 1.013073029 0.732213754 0.877553962 0.871253486 1.214871301 1.008857248 1 9.852379994 SDGAPAEGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 SDGAPAEGKR 10 1 F8WES8;C9JXU6;F5GZF3;C9JCL9;C9JXG5;F8WCP5;Q13769 F8WES8 THOC5 THO complex subunit 5 homolog 0 1 ; SDGAPAEGK(1)R;SDGAPAEGK(1)R 136.99 0.00016876 17590500 7577.6 6177.8 7049.7 6479.2 7407.5 9177 8477.3 9888.4 7451.1 6234.6 FALSE TRUE FALSE 6977.824964 6711.781504 7310.968084 6452.390787 7319.1704 7273.586754 8715.150223 12903.32764 6633.732972 6451.251886 1.081623395 1.040384351 1.133263468 1.00017654 1.134534898 1.127469037 1.350923879 2.000127707 1.028286151 1 12.65536343 -3.79186322 1.12946692 1.046609308 3.660741452 0.976360123 0.044157336 0.42936574 0.214351692 0.007073667 1.72086074 0.000161487 3.79186322 2.614132144 up NVMK(ac)DQRLVFHSK(ac)VR ddPTM_HeLa_Curcumin_4h_R1 1 NVMKDQRLVFHSKVR 15 3 H7C3H5;A2RRH5-2;A2RRH5;A2RRH5-4 H7C3H5 WDR27 WD repeat-containing protein 27 0 2 NVMK(1)DQRLVFHSK(1)VR 75.566 0.0050345 2349100 172.61 186.86 50.331 46.724 140.4 297.77 250.61 0 0 141.09 FALSE TRUE FALSE 158.9477364 203.0113458 52.19631114 46.53066847 138.7258217 236.0091454 257.6414421 0 0 145.992867 1.088736317 1.390556607 0.357526448 0.31871878 0.950223285 1.616579976 1.764753631 0 0 1 7.189754073 NVPEK(ac)HTR ddPTM_HeLa_Curcumin_4h_R1 2 NVPEKHTR 8 1 Q9UHB7;Q9UHB7-2 Q9UHB7 AFF4 AF4/FMR2 family member 4 0 1 ; NVPEK(1)HTR;NVPEK(1)HTR 135.43 0.0014386 1980910 2443.7 2007.19 2230.29 2567.8 1929.11 2354.27 1753.63 1096.74 2128.8 1747 FALSE TRUE FALSE 2250.278566 2180.68256 2312.946509 2557.175124 1906.106623 1865.967864 1802.832138 1431.130977 1895.275966 1807.70812 1.244824063 1.206324481 1.279491132 1.414595142 1.054432738 1.032228513 0.997302672 0.791682552 1.048441363 1 10.81994604 -4.46930034 1.23154213 1.155481489 0.72230108 0.50458867 0.119431405 0.855657056 1.39973814 0.021514894 0.425185394 3.39E-05 4.46930034 -0.43318041 NVPHEDICEDS(ph)DIDGDYR ddPTM_HeLa_Curcumin_4h_R1 4 NVPHEDICEDSDIDGDYR 18 0 O00629 O00629 KPNA4 Importin subunit alpha-3 1 0 NVPHEDICEDS(1)DIDGDYR;NVPHEDICEDS(1)DIDGDYR;NVPHEDICEDS(1)DIDGDYR;NVPHEDICEDS(1)DIDGDYR ;;; 212.55 8.70E-14 152432000 8583.5 8021.8 9286.9 9680.1 10457.3 11157.5 7289.7 6883.2 8622.4 7627.6 TRUE FALSE FALSE 7904.106918 8715.168648 9631.080684 9640.046311 10332.60353 8843.308729 7494.229363 8981.855994 7676.544292 7892.658532 1.001450511 1.104212049 1.220258123 1.221394068 1.309141082 1.1204474 0.949519016 1.138001341 0.972618321 1 12.94629562 -7.136579987 3.488904298 1.000472826 1.158312162 0.42089644 0.087848498 0.198314523 4.445335871 0.016068256 0.019885154 7.30E-08 7.136579987 0.157839336 NVPHEDICEDSDIDGDYR ddPTM_HeLa_Curcumin_4h_R1 2 NVPHEDICEDSDIDGDYR 18 0 O00629 O00629 KPNA4 Importin subunit alpha-3 0 0 ; ; 295.22 7.93E-82 55372000 4570.1 3936.4 4182.1 4285.1 4170.1 4688.6 3403.2 3171.1 4187 3860 FALSE FALSE TRUE 4208.371763 4276.644876 4337.092305 4267.369392 4120.374281 3716.131509 3498.684633 4137.953792 3727.696575 3994.134713 1.053637913 1.070731256 1.085865304 1.068408979 1.031606237 0.930397139 0.875955591 1.036007569 0.933292651 1 11.96366728 -5.277680081 9.149072612 1.037724077 0.940276996 0.342308422 0.055105959 0.176706494 93.64826745 0.006677077 0.015343486 5.28E-06 5.277680081 -0.097447081 NVPNWHR ddPTM_HeLa_Curcumin_4h_R1 2 NVPNWHR 7 0 F5H018;B5MDF5;J3KQE5;P62826;B4DV51 F5H018 RAN GTP-binding nuclear protein Ran 0 0 ; ; 121.29 0.0090754 106543000 18733.3 13815.1 15341.1 15354.1 17249.6 17583.5 15218.2 15193.3 16935.7 15294.4 FALSE FALSE TRUE 17250.53954 15009.21569 15909.65466 15290.5688 17043.90979 13936.48389 15645.18173 19825.66723 15077.89608 15825.87926 1.090020924 0.948396954 1.00529357 0.966174994 1.076964477 0.880613561 0.988582149 1.252737172 0.952736706 1 13.94999804 -11.76635655 12.30953489 0.402928089 1.028792105 0 0.098663333 0 0 0 0.012031723 1.71E-12 11.76635655 0.625864016 NVPQEES(ph)LEDSDVDADFK ddPTM_HeLa_Curcumin_4h_R1 1 NVPQEESLEDSDVDADFK 18 0 O00505 O00505 KPNA3 Importin subunit alpha-4 1 0 NVPQEES(0.938)LEDS(0.062)DVDADFK 175.77 1.80E-06 294020000 5951 5330.4 6045.2 5801.5 6586.6 7200.3 5097 4456.3 5667.3 5198.1 TRUE FALSE FALSE 5479.972071 5791.136024 6269.24043 5777.49493 6508.059097 5706.876616 5240.008102 5815.005356 5045.611369 5378.733588 1.018821992 1.076672776 1.16556069 1.07413666 1.209961228 1.061007489 0.974208523 1.081110499 0.938066793 1 12.39305082 -7.250182738 3.65498575 1.008260858 1.093643817 0.361165373 0.06297498 0.221294105 6.416138958 0.010486525 0.012484405 5.62E-08 7.250182738 0.085382959 NVPQEESLEDS(ph)DVDADFK ddPTM_HeLa_Curcumin_4h_R1 5 NVPQEESLEDSDVDADFK 18 0 O00505 O00505 KPNA3 Importin subunit alpha-4 1 0 NVPQEESLEDS(1)DVDADFK;NVPQEES(0.002)LEDS(0.998)DVDADFK;NVPQEES(0.001)LEDS(0.999)DVDADFK;NVPQEESLEDS(1)DVDADFK;NVPQEESLEDS(1)DVDADFK ;;;; 201.48 5.36E-12 388612200 31181.5 26871.4 29781.7 29593.9 32002.2 33779.7 25328.7 20044.1 28303.1 25068.1 TRUE FALSE FALSE 28713.45137 29194.04408 30885.436 29471.44828 31620.59467 26773.40944 26039.35515 26155.45382 25198.32074 25939.21461 1.106951456 1.125479106 1.190685087 1.136173501 1.21902668 1.032159603 1.003860585 1.008336382 0.971437305 1 14.66284718 -2.718558634 10.7943063 1.0746824 0.703702938 0 0.08316091 0 0 0.011620298 0 0.001911795 2.718558634 -0.370979462 NVPQEESLEDSDVDADFK ddPTM_HeLa_Curcumin_4h_R1 2 NVPQEESLEDSDVDADFK 18 0 O00505 O00505 KPNA3 Importin subunit alpha-4 0 0 ; ; 190.11 6.51E-08 10915300 7642 6542 6478.8 6433.3 6915.5 7477.6 6617.1 6718.4 6784.1 6355.8 FALSE FALSE TRUE 7037.127636 7107.461329 6718.910027 6406.680709 6833.037179 5926.66147 6802.758017 8766.809232 6039.901203 6576.663577 1.070014842 1.080709275 1.021628969 0.974153632 1.03898232 0.901165371 1.034378289 1.333017742 0.918383787 1 12.68314016 -4.263426185 6.347628994 1.023588778 1.339556594 0.730166894 0.058933033 0.043217711 9.831662686 0.007201675 0.058877138 5.45E-05 4.263426185 0.315967816 NVQQTVSAK(ac)GPPEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 NVQQTVSAKGPPEKR 15 2 G3V4A5;A0A087WYL7;O75586;O75586-2 G3V4A5 MED6 Mediator of RNA polymerase II transcription subunit 6 0 2 ; NVQQTVSAK(1)GPPEK(1)R;NVQQTVSAK(1)GPPEK(1)R 246.86 8.98E-61 20436000 1767.43 1990.32 2052.13 1755.73 1406.04 1809.37 1068.58 1087.83 1920.2 1748.28 FALSE TRUE FALSE 1627.536051 2162.354392 2128.183743 1748.465254 1389.273891 1434.086266 1098.561479 1419.504359 1709.558864 1809.0326 0.899672041 1.195309798 1.176420891 0.966519484 0.767965094 0.792736552 0.607264611 0.784675942 0.945012746 1 10.82100269 -5.728648956 3.663160228 0.992204042 0.725511834 0.64692954 0.103969536 0.138249637 3.894580626 0.017460301 0.035342402 1.87E-06 5.728648956 -0.266692208 NVQQTVSAK(ac)GPPEKR ddPTM_HeLa_Curcumin_4h_R1 2 NVQQTVSAKGPPEKR 15 2 G3V4A5;A0A087WYL7;O75586;O75586-2 G3V4A5 MED6 Mediator of RNA polymerase II transcription subunit 6 0 1 ; NVQQTVSAK(1)GPPEKR;NVQQTVSAK(1)GPPEKR 178.47 6.27E-08 31502000 5293.5 4521.8 4150.4 5199.6 4860.7 5664.1 5166.8 6260.7 5764 5018.9 FALSE TRUE FALSE 4874.513889 4912.644243 4304.217475 5178.085433 4802.739327 4489.301812 5311.766502 8169.558609 5131.703621 5193.306401 0.938614731 0.945956942 0.828800988 0.997069118 0.92479414 0.864440005 1.022810151 1.573093898 0.988138042 1 12.34243763 -4.268035536 3.892588349 0.951022261 1.628809354 0.924184007 0.05426752 0.046632482 1.411491479 0.007825438 0.088719354 5.39E-05 4.268035536 0.677787093 NVS(ph)EELDRTPPEVSK ddPTM_HeLa_Curcumin_4h_R1 1 NVSEELDRTPPEVSK 15 1 Q15393;Q15393-3 Q15393 SF3B3 Splicing factor 3B subunit 3 1 0 NVS(0.927)EELDRT(0.014)PPEVS(0.059)K 140.77 5.41E-05 0 1906.6 1450.9 1571.1 1574.9 1657 2372 1663.1 1279.5 1965.6 1642.2 TRUE FALSE FALSE 1755.690598 1576.309331 1629.326348 1568.383481 1637.241357 1880.020462 1709.76211 1669.61366 1749.978598 1699.266328 1.033205078 0.927641127 0.958841072 0.922976849 0.96349897 1.106371868 1.006176655 0.982549723 1.029843627 1 10.73069627 -2.88109121 13.27979848 1.001365106 0.993401465 0 0.052964464 0 0 0.007240566 0 0.001314949 2.88109121 -0.007963641 NVS(ph)SFPDDATSPLQENR ddPTM_HeLa_Curcumin_4h_R1 1 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 0 NVS(0.325)S(0.325)FPDDAT(0.325)S(0.024)PLQENR 170.79 6.09E-05 24185000 1017 1031.3 1164.7 1111.9 1198.7 1337 1291.9 636.83 1471.3 1186.5 TRUE FALSE FALSE 936.5033769 1120.440977 1207.864807 1107.299252 1184.406285 1059.691129 1328.147237 830.9965354 1309.902071 1227.730787 0.762792126 0.91261129 0.983818944 0.901907213 0.964711725 0.863129882 1.081790285 0.676855663 1.0669294 1 10.26177853 -4.225019086 23.30354645 0.90800575 0.676854345 0.349586481 0.098001629 7601.564934 4863647.011 0.014212381 3.861699792 5.96E-05 4.225019086 -0.231151405 NVSGISFT(ph)ENMGSSQQK ddPTM_HeLa_Curcumin_4h_R1 1 NVSGISFTENMGSSQQK 17 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 NVS(0.005)GIS(0.389)FT(0.572)ENMGS(0.033)S(0.001)QQK 101.71 0.00087397 0 1266 1379.6 1418.9 1566.4 1685.4 1626.6 958.42 980.29 1716.1 1495 TRUE FALSE FALSE 1165.794764 1498.846477 1471.485682 1559.918652 1665.302706 1289.224824 985.3106857 1279.175908 1527.848123 1546.951139 0.753608007 0.968903567 0.951216651 1.008382626 1.076506338 0.83339725 0.636937173 0.8269013 0.987651184 1 10.59521191 -4.996275874 24.24809279 0.91515515 0.732731135 0.432081364 0.097729831 74.40293694 484416.4973 0.016793854 0.050019565 1.01E-05 4.996275874 -0.182424015 NVSGISFTENMGS(ph)SQQK ddPTM_HeLa_Curcumin_4h_R1 1 NVSGISFTENMGSSQQK 17 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 NVSGIS(0.001)FT(0.061)ENMGS(0.919)S(0.019)QQK 94.538 0.0037463 4982400 1888.3 1416 1693.6 1908.9 1598.5 2331.2 1636.7 1058.8 1767.5 1740.3 TRUE FALSE FALSE 1738.839062 1538.39273 1756.366306 1901.001478 1579.438932 1847.682842 1682.621397 1381.623246 1573.609672 1800.775295 0.965605796 0.854294666 0.975338961 1.05565724 0.877088294 1.026048528 0.934387206 0.767238005 0.873851211 1 10.81440245 -4.28912279 3.460721718 0.973571646 0.747526612 0.384748169 0.066253743 0.15527235 3.200186667 0.00773006 0.087917679 5.14E-05 4.28912279 -0.226045033 NVSHNPLLLLT(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 2 NVSHNPLLLLTPQK 14 0 P47712 P47712 PLA2G4A Cytosolic phospholipase A2;Phospholipase A2;Lysophospholipase 1 0 NVSHNPLLLLT(1)PQK;NVSHNPLLLLT(1)PQK ; 155.94 0.00036381 37319000 6426.9 4923.5 5133.6 5405.7 5184.9 7053.9 4725.6 5298.4 5680.2 5255.1 TRUE FALSE FALSE 5918.204083 5349.065401 5323.855732 5383.332646 5123.073454 5590.841626 4858.187618 6913.857769 5057.096271 5437.714334 1.088362448 0.983697391 0.979061312 0.989999164 0.942137291 1.028160231 0.893424575 1.271463954 0.930004035 1 12.40878465 -10.02900138 2.574168021 0.999412837 1.030039585 0.02072951 0.0997336 1.581050988 19.0440396 0.077072276 0.013457817 9.35E-11 10.02900138 0.030626748 NVSIGIVGK ddPTM_HeLa_Curcumin_4h_R1 1 NVSIGIVGK 9 0 P25786;P25786-2;F5GX11 P25786 PSMA1 Proteasome subunit alpha type-1 0 0 133.13 0.0004416 7328800 3735.1 2399.8 3410.5 3079.9 3139.7 4814.7 3869 3903.8 3818.5 2981.7 FALSE FALSE TRUE 3439.462894 2607.228019 3536.89613 3067.15619 3102.261128 3816.076947 3977.553727 5094.050649 3399.620103 3085.313853 1.114785418 0.845044667 1.146365102 0.994114808 1.005492885 1.236852109 1.289189339 1.651064006 1.101871727 1 11.59120154 -4.112820506 1.009422233 1.03843522 2.104062378 0.825944197 0.087602494 0.692718417 0.448579862 0.012990045 0.853227764 7.71E-05 4.112820506 1.065627158 NVSS(ph)FPDDATS(ph)PLQENR ddPTM_HeLa_Curcumin_4h_R1 1 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 2 0 NVS(0.189)S(0.818)FPDDAT(0.203)S(0.79)PLQENR 88.283 0.012306 3840100 1426.8 1495.6 1415.7 1521.2 1326.7 2248.5 1879 945.79 1644.4 1583.1 TRUE FALSE FALSE 1313.867274 1624.873 1468.167087 1514.905677 1310.879969 1782.135754 1931.719683 1234.157017 1464.013434 1638.112607 0.802061634 0.991917767 0.896255289 0.924787265 0.800238008 1.087920175 1.179234977 0.753401818 0.893719655 1 10.67781882 -5.248718866 24.96684457 0.905570474 1.024090585 0.137681873 0.118403851 1078.595895 2116980.591 0.01703952 0.043146891 5.64E-06 5.248718866 0.118520111 NVSS(ph)FPDDATSPLQENR ddPTM_HeLa_Curcumin_4h_R1 2 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 0 NVS(0.006)S(0.994)FPDDATSPLQENR;NVS(0.044)S(0.956)FPDDATSPLQENR ; 304.62 3.01E-95 34093700 4819.5 3964.6 4743.7 4928.9 4099.7 6124.9 4526.1 2137.67 4761.4 4451.7 TRUE FALSE FALSE 4438.031489 4307.282358 4919.505695 4908.505518 4050.813755 4854.526698 4653.090185 2789.435742 4239.086332 4606.396244 0.963449789 0.935065533 1.067972757 1.065584734 0.879388906 1.053866502 1.010136762 0.605557055 0.920260896 1 12.1694228 -4.259579822 24.91564036 0.989667007 0.605556919 0.780068516 0.060983427 48.01703678 643311.045 0.007462918 0.064745005 5.50E-05 4.259579822 -0.384110088 NVSSFPDDAT(ph)SPLQENR ddPTM_HeLa_Curcumin_4h_R1 1 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 0 NVSSFPDDAT(0.77)S(0.23)PLQENR 198.67 1.18E-07 35373000 1732.3 1361.7 1800 2022.3 1600.1 2915.6 1826.4 1204.4 2260.5 1731.5 TRUE FALSE FALSE 1595.186627 1479.39928 1866.709583 2013.932258 1581.019853 2310.871694 1877.643868 1571.616016 2012.528805 1791.669496 0.890335316 0.825709922 1.041882773 1.124053439 0.882428292 1.289786816 1.04798562 0.877179647 1.123270118 1 10.80708882 -6.563472358 24.43999117 0.937398929 1.052521971 0.077356667 0.132009521 152.8296545 92012.69602 0.018425616 0.026057775 2.73E-07 6.563472358 0.115123041 NVSSFPDDATS(ph)PLQENR ddPTM_HeLa_Curcumin_4h_R1 4 NVSSFPDDATSPLQENR 17 0 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 0 NVSSFPDDAT(0.009)S(0.991)PLQENR;NVSSFPDDAT(0.081)S(0.919)PLQENR;NVSSFPDDAT(0.233)S(0.767)PLQENR;NVSSFPDDAT(0.217)S(0.783)PLQENR ;;; 244.18 1.32E-30 1816218000 14633.6 12180.5 13013 14638.5 14284.4 19608.3 13312.1 9752 15413.1 11645.5 TRUE FALSE FALSE 13475.33512 13233.32814 13495.27323 14577.92977 14114.06786 15541.31755 13685.6017 12725.33991 13722.32149 12050.18026 1.118268344 1.098185078 1.119922934 1.209768605 1.171274417 1.289716603 1.135717591 1.056029008 1.138764832 1 13.55676711 -8.419035707 0.427178781 0.986604132 1.174202728 0.094979883 0.071928545 0.772419219 0.297722599 0.062205082 0.023821541 3.81E-09 8.419035707 0.187598596 NVSTCEVSSSQAISS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 2 NVSTCEVSSSQAISSPQR 18 0 Q9H2X6-3;Q9H2X6 Q9H2X6-3 HIPK2 Homeodomain-interacting protein kinase 2 1 0 NVSTCEVSSSQAIS(0.068)S(0.932)PQR;NVSTCEVSSSQAIS(0.006)S(0.994)PQR ; 212.34 1.15E-44 7393000 3230.1 3187.1 3114.1 3382.8 2663.8 3950.4 3309.9 1548.42 3339.1 3053.5 TRUE FALSE FALSE 2974.434177 3462.578723 3229.511285 3368.80287 2632.035925 3131.04251 3402.766886 2020.52613 2972.809084 3159.608898 0.941393151 1.095888395 1.022123747 1.066208819 0.833025862 0.990958885 1.076958255 0.63948615 0.940878818 1 11.62553027 -4.252164383 24.87455669 0.986812905 0.639485954 0.671852823 0.074557805 522.9774414 1402538.918 0.009927325 0.165256015 5.60E-05 4.252164383 -0.347326951 NVSTGS(ph)AENEEK ddPTM_HeLa_Curcumin_4h_R1 2 NVSTGSAENEEK 12 0 O60271-3;O60271;A0A087X2D8;O60271-5;O60271-9;O60271-4;O60271-2 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 NVS(0.088)T(0.064)GS(0.847)AENEEK;NVS(0.001)T(0.013)GS(0.985)AENEEK ; 174.24 0.0001392 47112000 4089.4 4341.2 4507.6 3968.2 4757.1 4900.3 3856 4220.8 3408.9 3569.3 TRUE FALSE FALSE 3765.719675 4716.433984 4674.655621 3951.78064 4700.374689 3883.922542 3964.188982 5507.70249 3034.952199 3693.332909 1.019599307 1.277012958 1.265701126 1.06997683 1.272664773 1.051603697 1.07333649 1.491255358 0.821738054 1 11.85070759 -7.282886584 19.47126762 1.009254965 1.201458997 0.419107287 0.137986394 37.61920718 34152.94104 0.019971852 0.02287078 5.21E-08 7.282886584 0.192204032 STDS(ph)PVPGSEDDLVAGATLHSPEWSEER ddPTM_HeLa_Curcumin_4h_R1 2 STDSPVPGSEDDLVAGATLHSPEWSEER 28 0 Q9H694;Q9H694-2 Q9H694 BICC1 Protein bicaudal C homolog 1 1 0 S(0.139)T(0.164)DS(0.485)PVPGS(0.211)EDDLVAGATLHSPEWSEER;S(0.081)T(0.081)DS(0.419)PVPGS(0.419)EDDLVAGATLHSPEWSEER ; 122.78 1.03E-10 48400000 5821.4 4621.4 4392.7 4908.3 5388.4 6718.5 3853.1 737.92 5730.1 4812.6 TRUE FALSE FALSE 5360.630047 5020.853223 4555.497326 4887.990755 5324.146849 5325.007367 3961.207616 962.908411 5101.522366 4979.837492 1.076466864 1.008236359 0.914788351 0.981556278 1.069140681 1.069313482 0.795449173 0.193361412 1.024435511 1 12.28188295 -4.29531853 2.401639529 1.026319032 0.034744013 0.962586848 0.048970956 0.071773395 0.525784444 0.007836291 0.142210725 5.07E-05 4.29531853 -0.991575019 down NVT(ph)T(ph)GSLGEPQWLRVATGGR ddPTM_HeLa_Curcumin_4h_R1 1 NVTTGSLGEPQWLRVATGGR 20 1 F5GX99;A0A2R8Y6R5;A0A2U3TZY2;Q9H078-3;Q9H078-2;Q9H078 F5GX99 CLPB Caseinolytic peptidase B protein homolog 2 0 NVT(0.999)T(0.979)GS(0.023)LGEPQWLRVATGGR 62.203 0.012332 5237100 706.7 523.76 552 521.54 628.93 737.4 781.84 632.57 701.96 467.67 TRUE FALSE FALSE 650.7639493 569.0314806 572.4576056 519.3820057 621.4304205 584.4549278 803.7763262 825.437681 624.9567442 483.9214977 1.344771729 1.175875598 1.182955517 1.073277398 1.284155433 1.207747394 1.660964289 1.705726414 1.291442408 1 8.918629221 -4.761404909 4.233606702 1.171287229 1.69995497 0.797109209 0.098244578 0.077704446 3.206152118 0.018459878 0.068656386 1.73E-05 4.761404909 0.528667741 NVTELNEPLSNEER ddPTM_HeLa_Curcumin_4h_R1 4 NVTELNEPLSNEER 14 0 P61981 P61981 YWHAG "14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed" 0 0 ;;; ;;; 293.76 2.68E-76 72950800 7030.9 5624.8 6102.7 6485 5755.7 8116.2 6412.1 6443.8 7280.5 6445.3 FALSE FALSE TRUE 6474.396846 6110.982648 6328.87143 6458.166788 5687.067037 6432.808632 6592.006269 8408.484956 6481.847365 6669.273695 0.970779899 0.916289078 0.94895962 0.968346342 0.852726593 0.964544106 0.988414417 1.26077971 0.97189704 1 12.70331394 -4.259877413 4.194827875 0.966516335 1.284735337 0.831886714 0.041179973 0.075433542 2.960174644 0.006389611 0.071966736 5.50E-05 4.259877413 0.318219002 NVTLPAVFK ddPTM_HeLa_Curcumin_4h_R1 2 NVTLPAVFK 9 0 P36578;H3BTP7;H3BU31 P36578 RPL4 60S ribosomal protein L4 0 0 ; ; 108.98 0.0039553 4180600 4287.1 3000.31 3860.9 3411.5 3811.7 4846.5 3141.84 3722.2 3504.6 3250.4 FALSE FALSE TRUE 3947.771511 3259.643427 4003.98835 3397.384117 3766.247967 3841.281269 3229.991575 4857.081645 3120.154148 3363.351158 1.173761325 0.969165357 1.190475856 1.010118765 1.11979029 1.142099379 0.960349194 1.444119694 0.927692055 1 11.7156837 -1 0.014060152 1.21E-06 2.448208848 0.207406074 0.131510577 9451.183064 10.3670629 733.7331105 1107.918707 0.1 1 2.448207642 NWDEWVPESR ddPTM_HeLa_Curcumin_4h_R1 1 NWDEWVPESR 10 0 H0YMJ0;B3KTM8;Q9UBU8-2;H0YLJ3 H0YMJ0 MORF4L1 Mortality factor 4-like protein 1 0 0 148.91 9.08E-06 0 1651.9 1373.4 1391.1 1345.4 1233.2 1749.1 1097.2 831.48 1778 1170.3 FALSE FALSE TRUE 1521.150372 1492.110576 1442.65539 1339.833091 1218.494895 1386.316944 1127.984479 1084.994424 1582.957848 1210.967838 1.256144321 1.232163671 1.191324282 1.106415092 1.006215737 1.144800795 0.931473524 0.895972949 1.307184055 1 10.24194483 -4.488125588 0.981074934 1.134940014 0.798970233 0.475993355 0.098051178 1.207406454 1.127435695 0.017400327 0.391010447 3.25E-05 4.488125588 -0.335969782 NWEDEDFYDS(ph)DDDTFLDR ddPTM_HeLa_Curcumin_4h_R1 1 NWEDEDFYDSDDDTFLDR 18 0 A0A087X0M4;Q9BWU0;A0A087WWF4 A0A087X0M4 SLC4A1AP Kanadaptin 1 0 NWEDEDFY(0.002)DS(0.972)DDDT(0.026)FLDR 100.62 0.00067129 1670900 1052.9 1151.6 1084 1157.6 1083.2 1316.8 1056 1097.3 1258.3 1125.4 TRUE FALSE FALSE 969.561854 1251.139173 1124.173994 1152.810158 1070.283547 1043.680837 1085.628518 1431.861719 1120.267638 1164.507566 0.832593864 1.074393339 0.965364267 0.98995506 0.919086813 0.896242212 0.932264031 1.229585586 0.962009755 1 10.1855043 -4.260982753 24.5664412 0.936060804 1.229585673 0.623697099 0.0634462 16.47494581 885989.0628 0.010578286 0.082950171 5.48E-05 4.260982753 0.293524869 NWGAVVRS(ph)PEGTPQK ddPTM_HeLa_Curcumin_4h_R1 1 NWGAVVRSPEGTPQK 15 1 C9J0I9;Q86WB0;Q86WB0-3;F8WAU5;F8WBD7;F8WDK5;F8WF13 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 NWGAVVRS(0.999)PEGT(0.001)PQK 116.58 0.015104 19354000 1570.5 1062.9 1002.4 1393 984.86 1582.3 1133.7 929.75 1558.8 1410.5 TRUE FALSE FALSE 1446.193268 1154.77234 1039.549826 1387.236135 973.1161877 1254.113144 1165.508571 1213.226495 1387.80354 1459.51477 0.99087265 0.791202915 0.712257147 0.950477627 0.666739527 0.859267182 0.798558942 0.831253318 0.95086639 1 10.5112731 -7.264269831 22.44870279 0.995689881 0.800637311 0.549511396 0.073966782 26.0030412 206233.802 0.010989565 0.012876088 5.44E-08 7.264269831 -0.195052569 NWS(ph)LSQVNVSHAR ddPTM_HeLa_Curcumin_4h_R1 1 NWSLSQVNVSHAR 13 0 P55291 P55291 CDH15 Cadherin-15 1 0 NWS(0.778)LS(0.222)QVNVSHAR 92.151 0.011067 91662000 1521.6 1274 990.46 949.43 1178.5 1369.6 1061.9 1202.2 1058.3 990.49 TRUE FALSE FALSE 1401.163754 1384.118883 1027.167319 945.5015102 1164.447157 1085.529521 1091.694056 1568.745246 942.2071377 1024.909454 1.367109796 1.350479184 1.00220299 0.922521991 1.136146372 1.059146754 1.065161466 1.530618378 0.919307685 1 10.00128074 -9.727428424 1.657419418 1.000283016 1.196875421 0.176338697 0.180369448 0.653673585 3.251884813 0.13732625 0.030142761 1.87E-10 9.727428424 0.196592405 NWTEDMEGGIS(ph)SPVK ddPTM_HeLa_Curcumin_4h_R1 4 NWTEDMEGGISSPVK 15 0 A0A286YEX4;P08651-4;P08651-5;P08651-3;P08651-6;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 0 NWTEDMEGGIS(0.963)S(0.037)PVK;NWTEDMEGGIS(0.634)S(0.366)PVK;NWTEDMEGGIS(0.974)S(0.026)PVK;NWT(0.001)EDMEGGIS(0.768)S(0.231)PVK ;;; 135.55 0.00072186 133256000 13344.6 10794.6 12402.2 12945.3 12918 15443.9 11668.7 9041.15 14002.4 11851.8 TRUE FALSE FALSE 12288.36083 11727.63712 12861.83644 12891.73578 12763.96129 12240.66105 11996.09232 11797.75501 12466.37175 12263.64917 1.002015033 0.956292614 1.048777266 1.051215311 1.04079635 0.998125508 0.978182933 0.962010153 1.016530364 1 13.58210071 -4.703382503 2.936921947 1.007679763 0.965464125 0.28022889 0.027472665 0.307063548 5.140269985 0.00410325 0.019376434 1.98E-05 4.703382503 -0.042215638 NWTEDMEGGISS(ph)PVKK ddPTM_HeLa_Curcumin_4h_R1 2 NWTEDMEGGISSPVKK 16 1 A0A286YEX4;P08651-4;P08651-5;P08651-3;P08651-6;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 0 NWTEDMEGGIS(0.079)S(0.921)PVKK;NWTEDMEGGIS(0.022)S(0.978)PVKK ; 215.93 5.68E-15 114544000 12682 9984.9 11762.2 12020 11537.2 14000.8 10968.2 7788.1 12767.6 11704.1 TRUE FALSE FALSE 11678.20632 10847.95026 12198.11748 11970.26442 11399.62643 11096.87626 11275.93817 10162.65584 11367.02622 12110.8166 0.964279016 0.895724097 1.007208504 0.988394492 0.941276447 0.916278119 0.931063407 0.839138777 0.938584622 1 13.56400853 -1.876291015 0.395838075 0.982608835 2.07E-12 0.488719123 0.034868605 16.11281783 0.375117759 0.008221404 11.22737351 0.013295632 1.876291015 -0.982608835 NY(ph)ENHS(ph)S(ph)GGK ddPTM_HeLa_Curcumin_4h_R1 1 NYENHSSGGK 10 0 F5H6B2;Q9UHN6-2;Q9UHN6 F5H6B2 TMEM2 Transmembrane protein 2 3 0 NY(1)ENHS(1)S(1)GGK 70.412 0.0072262 0 136.64 219.64 345.7 364.41 204.3 351.53 358.11 156.07 281.18 258.08 TRUE FALSE FALSE 125.8247998 238.6247029 358.5119461 362.902168 201.8638559 278.6187154 368.1576028 203.6550245 250.3352575 267.0482608 0.471168767 0.893563966 1.342498712 1.358938519 0.755907772 1.043327205 1.378618238 0.762615057 0.937415794 1 8.060956678 -6.99265525 23.58908814 0.746700043 1.112440557 0.232746576 0.248044264 89.19409948 286460.3174 0.044904565 0.058931641 1.02E-07 6.99265525 0.365740514 NY(ph)SVVFPHDEPLAGRNMR ddPTM_HeLa_Curcumin_4h_R1 1 NYSVVFPHDEPLAGRNMR 18 1 A0A0A0MT55;Q5SYV1;Q9UL12-2;Q9UL12 A0A0A0MT55 SARDH "Sarcosine dehydrogenase, mitochondrial" 1 0 NY(0.936)S(0.064)VVFPHDEPLAGRNMR 62.89 0.0088579 0 2382.1 1728.8 1751.5 2835.5 1923.2 243.6 719.61 904.9 2697 1984.8 TRUE FALSE FALSE 2193.554271 1878.229769 1816.412131 2823.767452 1900.267096 193.0746141 739.8003199 1180.799844 2401.145848 2053.771652 1.068061422 0.914527069 0.884427501 1.374917922 0.925257243 0.094009777 0.360215469 0.574942128 1.169139639 1 11.00406007 -5.368740377 5.801626445 1.036018324 0.348192283 0.782291655 0.17103711 0.071929784 3.289184536 0.022581842 0.051147347 4.28E-06 5.368740377 -0.687826041 NYDPKVT(ph)PDPER ddPTM_HeLa_Curcumin_4h_R1 1 NYDPKVTPDPER 12 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 0 NYDPKVT(1)PDPER 136.83 0.015282 14897000 3754.7 3202.8 3126.7 3180.1 3463.2 4029.4 3003.2 2570.7 3983.7 3157.7 TRUE FALSE FALSE 3457.511533 3479.635761 3242.578253 3166.941589 3421.903602 3193.657019 3087.461709 3354.494596 3546.698077 3267.42984 1.058174682 1.064945823 0.992394148 0.969245475 1.047276841 0.977421758 0.944920583 1.026646251 1.085470309 1 11.67394054 -6.660649401 12.0687684 1.031044798 0.9914036 0.336524852 0.036086662 0.543375189 61.54435925 0.005590138 0.007905717 2.18E-07 6.660649401 -0.039641198 NYDPYKPLDIT(ph)PPPDQK ddPTM_HeLa_Curcumin_4h_R1 1 NYDPYKPLDITPPPDQK 17 1 Q9UKK3 Q9UKK3 PARP4 Poly [ADP-ribose] polymerase 4 1 0 NY(0.001)DPY(0.003)KPLDIT(0.996)PPPDQK 93.062 0.0028585 8543500 3857.4 3294.3 3352.3 2778.9 2783.2 3685.8 2499.9 1762.2 3796.1 3124.5 TRUE FALSE FALSE 3552.08272 3579.044613 3476.539187 2767.401648 2750.012158 2921.323532 2570.040466 2299.486668 3379.677327 3233.076142 1.098669677 1.10700907 1.075303839 0.855965504 0.850586883 0.903573997 0.794921107 0.711238018 1.04534418 1 11.65869177 -6.201490683 4.472647715 1.055369396 0.824174446 0.834107336 0.05398126 0.081207981 3.355365024 0.009672224 0.016167345 6.29E-07 6.201490683 -0.23119495 NYGSPLIS(ph)GSTPK ddPTM_HeLa_Curcumin_4h_R1 1 NYGSPLISGSTPK 13 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 0 NYGS(0.011)PLIS(0.843)GS(0.073)T(0.073)PK 155.14 0.00039183 30222000 7885 5712.1 6422.3 6105 6510.5 7268.7 5534.9 3924.5 7402.1 6016.3 TRUE FALSE FALSE 7260.89393 6205.828471 6660.316088 6079.739128 6432.86654 5761.089685 5690.194398 5121.061984 6590.108149 6225.365977 1.166340093 0.996861629 1.069867396 0.976607504 1.033331464 0.925421848 0.914033716 0.822612197 1.058589675 1 12.60394294 -4.797766797 0.659774302 1.073584407 0.769366617 0.691023883 0.050315823 0.962006195 0.429792062 0.012309825 0.19123777 1.59E-05 4.797766797 -0.30421779 SGS(ph)GNFGGGR ddPTM_HeLa_Curcumin_4h_R1 2 SGSGNFGGGR 10 0 F8W6I7;P09651-2;P09651;F8VZ49;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 1 0 S(0.001)GS(0.999)GNFGGGR;S(0.006)GS(0.994)GNFGGGR ; 97.957 0.013932 102127000 5642 6340.8 5386.6 4715.9 4894.4 6066.3 3845.7 855.4 5559 4979.9 TRUE FALSE FALSE 5195.429747 6888.870498 5586.232135 4696.386855 4836.037477 4808.080999 3953.599992 1116.207522 4949.191608 5152.951154 1.008243546 1.336878672 1.084084046 0.911397511 0.938498606 0.933073273 0.767249654 0.216615196 0.960457699 1 12.3311832 -4.295272493 1.567321104 1.023828397 1.00E-18 0.823722563 0.113827375 0.316845377 0.755295088 0.016915602 0.485527865 5.07E-05 4.295272493 -1.023828397 down NYGSPLISGST(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 NYGSPLISGSTPK 13 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 0 NYGS(0.006)PLIS(0.002)GS(0.013)T(0.979)PK 144.51 0.0023045 6690500 2599.8 2997.2 2744.4 2545 2909.7 3779.3 2456.1 1413.5 3029.8 2725.1 TRUE FALSE FALSE 2394.023087 3256.264613 2846.109878 2534.469464 2875.003728 2995.430579 2525.011556 1844.469643 2697.43852 2819.797022 0.849005467 1.154786883 1.009331472 0.898812732 1.019578255 1.062285886 0.895458622 0.654114331 0.956607337 1 11.4613756 -4.302083441 3.554458723 0.961113308 0.630448339 0.573086321 0.084888418 0.167093467 3.686656827 0.013404401 0.137005315 4.99E-05 4.302083441 -0.330664969 NYGYNPS(ph)PVKPEGLR ddPTM_HeLa_Curcumin_4h_R1 4 NYGYNPSPVKPEGLR 15 1 E9PRF4;Q15047-3;Q15047 E9PRF4 SETDB1 Histone-lysine N-methyltransferase SETDB1 1 0 NYGYNPS(1)PVKPEGLR;NYGYNPS(1)PVKPEGLR;NY(0.001)GY(0.017)NPS(0.983)PVKPEGLR;NYGY(0.004)NPS(0.995)PVKPEGLR ;;; 104.16 0.0012443 230665000 13231.4 10504.9 11009.9 12109.6 11530.8 14120.5 11922.3 5560.43 13511.6 11552 TRUE FALSE FALSE 12184.12073 11412.89675 11417.93658 12059.49368 11393.30274 11191.74913 12256.80765 7255.77951 12029.41128 11953.43114 1.019299027 0.95477998 0.955201602 1.008872979 0.953140785 0.936279215 1.025379869 0.607003916 1.006356346 1 13.54513717 -4.258642819 24.9983878 0.994277008 0.607003777 0.926291922 0.031824575 50.38119291 450331.6897 0.004776582 0.044097355 5.51E-05 4.258642819 -0.387273231 NYILDQTNVYGS(ph)AQR ddPTM_HeLa_Curcumin_4h_R1 2 NYILDQTNVYGSAQR 15 0 M0R3F1;A0A0A0MRA5;B7Z4B8;Q9BUJ2-3;Q9BUJ2-4;Q9BUJ2-2;Q9BUJ2 M0R3F1 HNRNPUL1 Heterogeneous nuclear ribonucleoprotein U-like protein 1 1 0 NYILDQTNVYGS(1)AQR;NYILDQT(0.002)NVYGS(0.998)AQR ; 197.73 7.79E-07 22658400 3542.5 2398.8 3245.4 3340.8 3204 4460 3514.1 3221.8 3860.8 3037.6 TRUE FALSE FALSE 3262.107387 2606.141583 3365.677379 3326.976655 3165.794393 3534.945725 3612.696188 4204.111989 3437.279899 3143.156374 1.037844446 0.829147924 1.070795398 1.058482703 1.00720232 1.12464838 1.149384809 1.337544649 1.093575849 1 11.61799833 -3.382023522 0.690446694 1.006472597 2.207360309 0.673472999 0.069853676 3.247636729 0.449462236 0.010495241 4.063967325 0.000414932 3.382023522 1.200887712 GPEDSWLLLSAPGPTPAS(ph)PRPASPCGK ddPTM_HeLa_Curcumin_4h_R1 1 GPEDSWLLLSAPGPTPASPRPASPCGK 27 1 Q14934-2;Q14934-9;Q14934-3;Q14934-4;Q14934-5;Q14934-6;Q14934-7;Q14934;Q14934-8;Q14934-10;Q14934-18;Q14934-11;Q14934-12;Q14934-13;Q14934-14;Q14934-15;Q14934-16;Q14934-17 Q14934-2 NFATC4 "Nuclear factor of activated T-cells, cytoplasmic 4" 1 0 GPEDSWLLLSAPGPT(0.442)PAS(0.539)PRPAS(0.019)PCGK 95.122 1.83E-06 16680000 1360.8 1123.7 1315 987 851.64 1427.3 657.7 315.19 1441.5 1073.3 TRUE FALSE FALSE 1253.091244 1220.827621 1363.735057 982.9160555 841.4847492 1131.261891 676.1532919 411.28998 1283.371056 1110.597095 1.128304089 1.099253389 1.227929609 0.885033879 0.757686791 1.018606924 0.608819611 0.370332303 1.155568533 1 10.11711981 -4.294517523 0.741154354 1.067864201 2.88E-17 0.781182911 0.120921459 0.917992414 0.364045203 0.020335192 0.805820881 5.08E-05 4.294517523 -1.067864201 down NYQQNYQNS(ph)ESGEK ddPTM_HeLa_Curcumin_4h_R1 4 NYQQNYQNSESGEK 14 0 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 0 NYQQNYQNS(1)ESGEK;NYQQNYQNS(0.999)ES(0.001)GEK;NYQQNYQNS(0.999)ES(0.001)GEK;NYQQNYQNS(0.963)ES(0.037)GEK ;;; 178.67 0.00015156 88435000 15973.1 16256.5 17268.6 17122.4 20932.7 20009.5 16505.8 16534.8 15749.2 15682.1 TRUE FALSE FALSE 14708.81228 17661.63942 17908.58951 17051.55205 20683.09122 15859.30415 16968.90832 21576.1844 14021.55216 16227.05181 0.906437747 1.088407163 1.103625583 1.05081023 1.274605607 0.977337371 1.045717271 1.329642911 0.864085006 1 13.98611329 -7.133521932 4.707705206 0.956058105 1.120545245 0.423687585 0.105735855 0.182256445 6.251931562 0.016567843 0.020425333 7.35E-08 7.133521932 0.16448714 NYQQNYQNS(ph)ESGEKNEGS(ph)ESAPEGQAQQR ddPTM_HeLa_Curcumin_4h_R1 1 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 2 0 NYQQNY(0.002)QNS(0.549)ES(0.477)GEKNEGS(0.867)ES(0.105)APEGQAQQR 108.23 1.22E-07 0 9664.7 8580.9 7677.4 9046.9 9045.2 10309 8000.9 4992.6 9286 8308.6 TRUE FALSE FALSE 8899.728797 9322.59476 7961.931198 9009.466325 8937.341898 8170.797194 8225.383721 6514.820757 8267.349032 8597.323232 1.035174386 1.084360156 0.926094202 1.047938536 1.039549364 0.950388507 0.956737754 0.757773156 0.961618961 1 13.06967183 -3.55095755 1.041457871 1.01842685 1.34E-14 0.727966463 0.045582965 2.180486962 0.641682941 0.005989171 3.53381701 0.000281218 3.55095755 -1.01842685 NYQQNYQNS(ph)ESGEKNEGSESAPEGQAQQR ddPTM_HeLa_Curcumin_4h_R1 5 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 0 NYQQNY(0.022)QNS(0.783)ES(0.186)GEKNEGS(0.006)ES(0.002)APEGQAQQR;NYQQNY(0.035)QNS(0.799)ES(0.152)GEKNEGS(0.01)ES(0.004)APEGQAQQR;NYQQNY(0.005)QNS(0.882)ES(0.113)GEKNEGSESAPEGQAQQR;NYQQNY(0.152)QNS(0.733)ES(0.114)GEKNEGSESAPEGQAQQR;NYQQNY(0.046)QNS(0.749)ES(0.194)GEKNEGS(0.008)ES(0.003)APEGQAQQR ;;;; 115.81 5.31E-13 1743883000 5856.1 5323.04 5424.78 5750.43 5692.21 6307.88 5744.96 5758.44 5912.6 5656.57 TRUE FALSE FALSE 5392.583506 5783.139859 5625.827119 5726.636244 5624.334113 4999.554584 5906.148116 7514.161847 5264.002573 5853.135386 0.921315355 0.988041362 0.9611647 0.978387798 0.960909622 0.854166913 1.009057151 1.283784049 0.899347482 1 12.51499393 -4.282424739 3.901040267 0.958229335 1.308458287 0.84100644 0.043640202 0.063251255 1.909861287 0.005963991 0.06058122 5.22E-05 4.282424739 0.350228952 NYQQNYQNSESGEKNEGS(ph)ESAPEGQAQQR ddPTM_HeLa_Curcumin_4h_R1 2 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 1 0 NYQQNY(0.004)QNS(0.036)ES(0.026)GEKNEGS(0.681)ES(0.253)APEGQAQQR;NYQQNYQNS(0.002)ES(0.013)GEKNEGS(0.765)ES(0.22)APEGQAQQR ; 90.836 6.99E-08 671627000 1149.82 1410.6 1170.89 1172.26 1131.96 1395.53 1036.26 675 1092.81 1143.29 TRUE FALSE FALSE 1058.810534 1532.525978 1214.284213 1167.409499 1118.462116 1106.081347 1065.334667 880.8043927 972.9314771 1183.019242 0.895007026 1.295436222 1.026428117 0.986805165 0.945430198 0.934964798 0.900521841 0.744539363 0.822413907 1 10.20825782 -3.853215526 0.995557621 0.984488057 0.413135543 0.302998053 0.115973704 3.760885968 1.66050036 0.017208718 2.785728537 0.000140212 3.853215526 -0.571352514 NYQQNYQNSESGEKNEGSESAPEGQAQQR ddPTM_HeLa_Curcumin_4h_R1 1 NYQQNYQNSESGEKNEGSESAPEGQAQQR 29 1 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 0 134.91 1.02E-15 1601300 194.74 208.5 178.21 407.14 146.66 187.98 189.92 180.58 247.14 170.44 FALSE FALSE TRUE 179.3261235 226.5218109 184.8146194 405.4553626 144.9111753 148.990829 195.2486441 235.6380107 220.0293603 176.3627773 1.01680256 1.284408277 1.047923049 2.298984903 0.821665305 0.844797475 1.107085333 1.336098321 1.247595233 1 7.462402291 -7.270324349 20.71688765 1.007934454 1.243974772 0.02154614 0.396939504 132.1196433 308059.4282 0.065351374 0.075522257 5.37E-08 7.270324349 0.236040318 LEQLCEEFS(ph)EEER ddPTM_HeLa_Curcumin_4h_R1 2 LEQLCEEFSEEER 13 0 Q9H3C7-3;Q9H3C7 Q9H3C7-3 GGNBP2 Gametogenetin-binding protein 2 1 0 LEQLCEEFS(1)EEER;LEQLCEEFS(1)EEER ; 213.83 2.09E-13 27494000 4685.2 3849.2 4033.1 4140.8 4452.2 4506.4 2972.26 1163.69 3568 3280.7 TRUE FALSE FALSE 4314.361476 4181.907696 4182.570234 4123.666467 4399.110423 3571.721842 3055.653616 1518.493724 3176.599327 3394.704081 1.270909444 1.231891675 1.232086843 1.214735178 1.295874491 1.05214527 0.900123705 0.447312546 0.935751468 1 11.7290701 -4.294203705 1.620984166 1.16245268 0.218297949 0.792365623 0.111915922 0.340510172 0.882633977 0.017620527 0.493432382 5.08E-05 4.294203705 -0.944154731 down NYSEVIEVDES(ph)DVEEDIFPTTSK ddPTM_HeLa_Curcumin_4h_R1 1 NYSEVIEVDESDVEEDIFPTTSK 23 0 F8W7U8;P49959-2;P49959;P49959-3 F8W7U8 MRE11A Double-strand break repair protein MRE11A 1 0 NYSEVIEVDES(0.999)DVEEDIFPT(0.001)TSK 90.084 9.39E-05 4046500 2660.5 2148.4 2139 2205.3 2369.8 2913 2362.7 2699.9 2805.3 2272.5 TRUE FALSE FALSE 2449.918618 2334.098123 2218.273222 2196.175053 2341.541683 2308.810964 2428.991003 3523.087081 2497.565609 2351.469206 1.041867192 0.992612668 0.943356271 0.93395867 0.995778162 0.981858898 1.032967388 1.498249296 1.062129839 1 11.19934672 -4.261514673 4.664241214 1.002960771 1.528101207 0.941784307 0.037348923 0.032534829 1.907038756 0.005519315 0.055543953 5.48E-05 4.261514673 0.525140436 NYTDEAIETDDLTIK ddPTM_HeLa_Curcumin_4h_R1 1 NYTDEAIETDDLTIK 15 0 O14818;O14818-2;H0Y586 O14818 PSMA7 Proteasome subunit alpha type-7 0 0 198.78 4.31E-06 3979500 1551.1 1136.1 1261.8 1590.1 1311.5 1568.5 1715.2 1874.4 1574.9 1558 FALSE FALSE TRUE 1428.328798 1234.299422 1308.563418 1583.520588 1295.861219 1243.175419 1763.323896 2445.895931 1402.13741 1612.140384 0.885982891 0.765627754 0.811693219 0.98224733 0.803814129 0.771133477 1.093778131 1.517173042 0.869736547 1 10.65476166 -4.34616713 3.003667682 0.905879853 1.563276847 0.833563872 0.087776484 0.108332917 1.513084636 0.014110709 0.151163729 4.51E-05 4.34616713 0.657396994 NYTEDIFPVT(ph)PPELEETIRDEK ddPTM_HeLa_Curcumin_4h_R1 2 NYTEDIFPVTPPELEETIRDEK 22 1 Q5T3J3-2;Q5T3J3 Q5T3J3-2 LRIF1 Ligand-dependent nuclear receptor-interacting factor 1 1 0 NYTEDIFPVT(1)PPELEETIRDEK;NYT(0.003)EDIFPVT(0.994)PPELEET(0.004)IRDEK ; 109.19 2.48E-05 9935500 3402 2301.3 2520.7 2768.7 2950.6 3816 2987.1 1893.35 3228.4 2682.2 TRUE FALSE FALSE 3132.72811 2500.214118 2614.119359 2757.243853 2915.416022 3024.518585 3070.909987 2470.623699 2874.252597 2775.40625 1.128745786 0.90084618 0.941887105 0.99345595 1.050446587 1.08975707 1.106472246 0.890184527 1.035615091 1 11.43848325 -7.28645398 24.98959524 1.060796614 1.003891049 0.105888603 0.075174151 1452.577021 1451119.891 0.014466216 0.016547513 5.17E-08 7.28645398 -0.056905565 NYTNS(ph)PEESSK ddPTM_HeLa_Curcumin_4h_R1 1 NYTNSPEESSK 11 0 J3QQU0;A0A3B3ITH3;Q9P2X3-2;Q9P2X3 J3QQU0 IMPACT Protein IMPACT 1 0 NY(0.004)T(0.03)NS(0.965)PEES(0.001)SK 94.781 0.014275 34613000 5117.7 5096.9 4786 5900.6 5118 6438.2 4699.8 3974.3 6718.9 6038 TRUE FALSE FALSE 4712.628645 5537.453325 4963.37337 5876.184881 5056.971193 5102.844747 4831.663739 5186.045775 5981.85348 6247.820051 0.754283671 0.886301667 0.794416825 0.940517626 0.809397702 0.816740032 0.773335932 0.830056841 0.957430501 1 12.60913719 -9.455656755 1.132676324 1.002212631 0.820742578 0.571872505 0.05252608 0.266104938 0.598636013 0.03876968 0.009140019 3.50E-10 9.455656755 -0.181470053 NYTNSPEESS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 NYTNSPEESSK 11 0 J3QQU0;A0A3B3ITH3;Q9P2X3-2;Q9P2X3 J3QQU0 IMPACT Protein IMPACT 1 0 NYTNS(0.006)PEES(0.281)S(0.713)K 149.57 0.00066708 35327000 3887.1 6393.4 4140.6 5401.8 3621 4392.5 3563.5 2754.1 7540.8 7093.6 TRUE FALSE FALSE 3579.431933 6946.017008 4294.054278 5379.448783 3577.82194 3481.445986 3663.482219 3593.812412 6713.593106 7340.102072 0.487654245 0.946310683 0.585012884 0.732884738 0.487434903 0.474304846 0.499105078 0.489613411 0.914645742 1 12.84158441 -13.52287875 0.245408199 3.60451277 0.524804641 0.553086897 0.137364576 26.03992521 0.342413051 32.89122723 0.089547338 3.00E-14 13.52287875 -3.079708128 NYVPPKGDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 NYVPPKGDKK 10 2 D6R9A6;P26583 D6R9A6 HMGB2 High mobility group protein B2 0 1 ; NYVPPKGDK(1)K;NYVPPK(0.007)GDK(0.993)K 82.261 0.0082047 9372500 7502.1 7166.6 7409.7 6814.8 8480.2 10531.8 8859.8 10308.2 10651.7 7628.4 FALSE TRUE FALSE 6908.300869 7786.04897 7684.31 6786.602163 8379.079154 8347.385962 9108.382143 13451.12273 9483.235159 7893.486332 0.875190072 0.986389112 0.973500134 0.85977246 1.061518168 1.057503061 1.153911182 1.704078801 1.201400086 1 12.94644692 -1.183464035 0.857540841 0.943429467 199.9998875 0.816335334 0.098376831 82.62767958 0.300249843 0.009780801 31988.78787 0.065544456 1.183464035 199.0564581 NYYEQWGK ddPTM_HeLa_Curcumin_4h_R1 2 NYYEQWGK 8 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 ; ; 157.68 6.35E-06 30726000 6095 5404.3 6595.7 5568.7 5404.1 8744.2 6508.9 5405 5204.4 4211 FALSE FALSE TRUE 5612.574319 5871.423611 6840.142444 5545.658195 5339.659637 6930.554353 6691.522216 7052.959618 4633.490341 4357.331937 1.288075914 1.347481371 1.569800636 1.272718782 1.225442476 1.590550009 1.535692555 1.618641802 1.063377867 1 12.0892293 -9.782960107 0.074235064 2.14E-13 2.150312216 0.713387977 0.112654253 28.27309767 0.436021814 9.159145949 4.10908148 1.65E-10 9.782960107 2.150312216 PAAAAAAGSAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 PAAAAAAGSASPR 13 0 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 0 PAAAAAAGS(0.004)AS(0.996)PR 130.69 0.0016064 4070900 1209.1 925.03 832.14 935.46 928.91 1028.1 745.98 483.79 832.07 936.43 TRUE FALSE FALSE 1113.398459 1004.985471 862.9798404 931.5893144 917.8333549 814.8604709 766.9101911 631.2953439 740.7940027 968.9708728 1.149052557 1.037167886 0.890614842 0.961421381 0.947224917 0.840954557 0.791468776 0.651511167 0.764516275 1 9.920309489 -4.55659152 0.504115429 1.067158323 0.471017597 0.361425297 0.110781328 1.157363115 0.237762671 0.016164636 0.383797082 2.78E-05 4.55659152 -0.596140727 PAANRAS(ph)GEWDSGTENR ddPTM_HeLa_Curcumin_4h_R1 1 PAANRASGEWDSGTENR 17 1 A0A0U1RQE4;A0A0U1RQN2;A0A494C1M0;Q5HYK7-3;Q5HYK7-2;Q5HYK7 A0A0U1RQE4 SH3D19 SH3 domain-containing protein 19 1 0 PAANRAS(1)GEWDSGTENR 55.972 0.018447 7868200 2004.8 2149.3 1844.8 1744.5 1484.7 2179.2 2107.5 1408.3 2271.3 2731.9 TRUE FALSE FALSE 1846.117965 2335.075915 1913.169911 1737.281721 1466.995922 1727.209355 2166.630778 1837.684187 2022.144073 2826.833322 0.653069267 0.826039476 0.676789076 0.614568149 0.51895381 0.611005022 0.766451549 0.650085795 0.715338983 1 11.4649711 -9.661250972 0.420617588 1.155079388 0.642638254 0.142545882 0.118462014 1.198079108 0.220648838 0.280623659 0.025568983 2.18E-10 9.661250972 -0.512441134 PAAS(ph)PAVGEK ddPTM_HeLa_Curcumin_4h_R1 1 PAASPAVGEK 10 0 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 0 PAAS(1)PAVGEK 110.66 0.0073218 7262700 3016.9 2716.9 3117.6 2914.7 2460.9 2408.6 2912.9 1656.3 2439.5 2519.4 TRUE FALSE FALSE 2778.109182 2951.73673 3233.140999 2902.639744 2431.555375 1909.029209 2994.628134 2161.298245 2171.892953 2606.948962 1.065655378 1.132257199 1.240201111 1.113424078 0.932720744 0.732284842 1.14870992 0.829052765 0.833116791 1 11.34814662 -5.686402593 6.894948949 1.0626459 0.913261501 0.228683835 0.138215535 0.238001376 17.93389318 0.017428098 0.034946646 2.06E-06 5.686402593 -0.149384399 PAASS(ph)PETPSAGQQEAK ddPTM_HeLa_Curcumin_4h_R1 1 PAASSPETPSAGQQEAK 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 PAAS(0.033)S(0.966)PET(0.001)PSAGQQEAK 166.79 9.69E-05 5668700 5920.8 4659.9 5638.2 6733.8 6254.9 5926.7 4252.8 2644.6 4417.3 4934.5 TRUE FALSE FALSE 5452.162432 5062.680992 5847.156652 6705.93732 6180.314403 4697.435612 4372.122122 3450.926366 3932.733242 5105.973508 1.067800768 0.991521202 1.145160006 1.313351374 1.210408631 0.919988246 0.856275912 0.675860609 0.770222022 1 12.31797034 -4.702025353 2.021751655 1.069047672 0.699337711 0.440816006 0.140472313 0.222088801 1.621619078 0.016941935 0.109090489 1.99E-05 4.702025353 -0.369709961 PAASSPET(ph)PSAGQQEAK ddPTM_HeLa_Curcumin_4h_R1 1 PAASSPETPSAGQQEAK 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 PAAS(0.008)S(0.058)PET(0.875)PS(0.058)AGQQEAK 96.229 0.0083881 7631100 2227.1 1820.8 2160.6 1956.4 2718.8 2231.8 1625.4 1178.9 1967.8 1865.8 TRUE FALSE FALSE 2050.822685 1978.181839 2240.673737 1948.304935 2686.380086 1768.899522 1671.004349 1538.341183 1751.937263 1930.636411 1.062252153 1.024626816 1.160588148 1.009151658 1.391447955 0.916226127 0.86551996 0.796805227 0.907440289 1 10.91486078 -5.01296052 24.65143449 1.062593021 0.846090105 0.404694011 0.123629655 366.328266 696776.3372 0.015764848 0.042493149 9.71E-06 5.01296052 -0.216502916 SGVS(ph)ITIDDPVR ddPTM_HeLa_Curcumin_4h_R1 1 SGVSITIDDPVR 12 0 S4R3H4;E7EQT4;Q9UKV3;G3V3B0;Q9UKV3-3;Q9UKV3-2;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 S(0.007)GVS(0.63)IT(0.363)IDDPVR 91.202 0.014221 3189900 1051.1 1005.5 943.4 1154.7 970.21 1969.9 1813 2140.5 1376.6 1108.7 TRUE FALSE FALSE 967.9043259 1092.41094 978.3632339 1149.922157 958.6408794 1561.320535 1863.867901 2793.128596 1225.590424 1147.227242 0.843690151 0.952218444 0.852806835 1.002349068 0.835615512 1.360951411 1.624671932 2.434677711 1.068306591 1 10.16393547 -4.245094544 1.058822265 0.917379682 3.235870388 0.9565016 0.099340237 0.223186528 0.190680102 0.013709052 0.585779886 5.69E-05 4.245094544 2.318490706 up T(ph)LSSSAQEDIIR ddPTM_HeLa_Curcumin_4h_R1 1 TLSSSAQEDIIR 12 0 Q9H788-2;Q9H788 Q9H788-2 SH2D4A SH2 domain-containing protein 4A 1 0 T(0.927)LS(0.035)S(0.035)S(0.003)AQEDIIR 247.73 1.51E-26 377160000 1210.6 878.49 1022.9 1175.8 960.49 1980.8 2201.7 9584.8 1028.8 908.76 TRUE FALSE FALSE 1114.779733 954.4227611 1060.809574 1170.934851 949.0367841 1569.959752 2263.473776 12507.1614 915.9432139 940.3393424 1.185507914 1.014976954 1.128113571 1.245225844 1.009249259 1.669567231 2.407081863 13.30068927 0.974056038 1 9.877037669 -4.245084047 3.235225991 1.134396978 15.2813215 0.996793016 0.205391612 0.015973039 0.254728756 0.033844029 0.576125648 5.69E-05 4.245084047 14.14692452 up PALAPKPTS(ph)QT(ph)PPAS(ph)PLSK ddPTM_HeLa_Curcumin_4h_R1 1 PALAPKPTSQTPPASPLSK 19 1 F5H1N7;Q6ZU35 F5H1N7 KIAA1211 Uncharacterized protein KIAA1211 3 0 PALAPKPT(0.499)S(0.573)QT(0.923)PPAS(0.898)PLS(0.106)K 58.83 0.0079837 0 634.63 545.64 841.56 578.46 776.92 766.06 554.79 388.42 942.09 711.29 TRUE FALSE FALSE 584.3983658 592.8026903 872.7489539 576.0664858 767.6557364 607.1705207 570.3559143 506.8474699 838.745084 736.0072746 0.794011671 0.805430477 1.185788489 0.782691294 1.043000203 0.824951793 0.774932442 0.688644647 1.139588035 1 9.523576215 -4.783185961 2.348076767 0.914030885 0.709131288 0.272259822 0.139981991 0.324920796 3.442603716 0.017899331 0.087611881 1.65E-05 4.783185961 -0.204899597 PAPAVGEAEDKENQQATSGPNQPS(ph)VR ddPTM_HeLa_Curcumin_4h_R1 2 PAPAVGEAEDKENQQATSGPNQPSVR 26 1 P16989-2;P16989;P16989-3 P16989-2 YBX3 Y-box-binding protein 3 1 0 PAPAVGEAEDKENQQAT(0.001)S(0.001)GPNQPS(0.998)VR;PAPAVGEAEDKENQQAT(0.138)S(0.138)GPNQPS(0.723)VR ; 79.04 5.07E-05 30796000 3602.8 2354.37 2656.6 2774.8 2857.8 4218.8 3433.3 2976.1 2264 2390.53 TRUE FALSE FALSE 3317.634578 2557.871252 2755.055933 2763.318613 2823.722601 3343.773324 3529.629158 3883.49919 2015.644864 2473.60074 1.341216683 1.034067952 1.113783599 1.117123943 1.141543401 1.351783766 1.426919511 1.569978181 0.814862654 1 11.27239694 -4.890223209 1.583202315 1.145567833 1.550661648 0.590748575 0.137824227 0.261831159 1.154326734 0.019401188 0.113093827 1.29E-05 4.890223209 0.405093815 PAPEASSLEEPHS(ph)PETGEK ddPTM_HeLa_Curcumin_4h_R1 1 PAPEASSLEEPHSPETGEK 19 0 Q5JTC6;Q5JTC6-2 Q5JTC6 AMER1 APC membrane recruitment protein 1 1 0 PAPEASSLEEPHS(0.933)PET(0.067)GEK 81.884 0.0019052 11695000 1391.1 1255.1 966.91 1185.8 1328 1444.2 789.26 605.09 945.23 1024.8 TRUE FALSE FALSE 1280.992967 1363.585251 1002.744535 1180.893474 1312.164467 1144.656641 811.4045114 789.5791555 841.5406338 1060.411724 1.208014716 1.285901712 0.945618115 1.113617897 1.237410374 1.079445478 0.765178745 0.744596781 0.79359801 1 10.05040881 -4.77171536 4.942113677 1.113730509 0.748008478 0.456341859 0.140580975 0.082871456 5.39963497 0.015758521 0.055145665 1.69E-05 4.77171536 -0.365722031 PAPPQEES(ph)PSSEAK ddPTM_HeLa_Curcumin_4h_R1 2 PAPPQEESPSSEAK 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 PAPPQEES(0.523)PS(0.379)S(0.098)EAK;PAPPQEES(0.529)PS(0.235)S(0.235)EAK ; 219.53 4.81E-14 102502000 3616.9 3045.5 3518.9 3073.1 3544.5 3507.3 3084 3309.4 3156.4 2611.14 TRUE FALSE FALSE 3330.618548 3308.73945 3649.31353 3060.384326 3502.234152 2779.846445 3170.52874 4318.420825 2810.150817 2701.876921 1.232705503 1.224607762 1.350658685 1.132688282 1.296222683 1.028857541 1.17345417 1.59830405 1.040073586 1 11.39974624 -13.06736489 0.20815284 3.49E-12 1.286714861 0.310865977 0.141800654 37.36967347 0.5471761 15.19327385 0.130937347 8.56E-14 13.06736489 1.286714861 PAPPQEESPS(ph)SEAK ddPTM_HeLa_Curcumin_4h_R1 1 PAPPQEESPSSEAK 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 PAPPQEES(0.259)PS(0.74)S(0.001)EAK 191.63 5.91E-06 23757000 1766.6 1581.5 1939.6 2009.8 2135 1879.1 1608.1 1634.9 1556.4 1266.1 TRUE FALSE FALSE 1626.771746 1718.197813 2011.483282 2001.48398 2109.541519 1489.353478 1653.218958 2133.373484 1385.666814 1310.096881 1.241718662 1.311504392 1.535369874 1.527737383 1.610217954 1.136826978 1.261905881 1.628408948 1.057682706 1 10.35545779 -7.893154041 0.75295648 1.037715077 1.435265539 0.533151217 0.150003761 0.332281051 0.414231589 0.051828563 0.040303034 1.28E-08 7.893154041 0.397550462 PARS(ph)PDAPGR ddPTM_HeLa_Curcumin_4h_R1 1 PARSPDAPGR 10 1 E7EUN2 E7EUN2 AGAP1 1 0 PARS(1)PDAPGR 79.089 0.014387 3192600 454.23 546.69 498.05 459.6 623.74 550.62 522.37 375.93 683.38 443.21 TRUE FALSE FALSE 418.2772162 593.9434476 516.5081711 457.698297 616.3023079 436.4152052 537.0262963 490.5493264 608.4149237 458.6115145 0.912051274 1.29509057 1.126243356 0.998008734 1.343843947 0.951601064 1.17098302 1.069640231 1.326645547 1 8.841128767 -7.289182119 24.99779339 0.958468651 1.132958209 0 0.163338695 569.0856614 512777.1904 0.018306102 0.020935976 5.14E-08 7.289182119 0.174489558 PAS(ph)PDRFAVSAEAENK ddPTM_HeLa_Curcumin_4h_R1 2 PASPDRFAVSAEAENK 16 1 G3V331;O15037 G3V331 KHNYN Protein KHNYN 1 0 PAS(1)PDRFAVSAEAENK;PAS(1)PDRFAVSAEAENK ; 94.673 0.0018762 17659800 8170.3 7802.4 8206.7 9074 7769.2 6116.1 6505.5 4174.2 7468.3 8161.5 TRUE FALSE FALSE 7523.612134 8476.804689 8510.847521 9036.454192 7676.557364 4847.551917 6688.026821 5446.894364 6649.046175 8445.111518 0.890883693 1.003752842 1.007783912 1.070021891 0.908994197 0.574006857 0.791940616 0.644976014 0.787324852 1 13.04390076 -5.395118112 5.508434229 0.965248761 0.684272913 0.682040302 0.088598062 0.082187834 3.346609962 0.01049942 0.023800128 4.03E-06 5.395118112 -0.280975847 ARS(ph)APPMEGAR ddPTM_HeLa_Curcumin_4h_R1 2 ARSAPPMEGAR 11 1 Q86YD1 Q86YD1 PTOV1 Prostate tumor-overexpressed gene 1 protein 1 0 ARS(1)APPMEGAR;ARS(1)APPMEGAR ; 99.161 0.0050719 35679000 2756.9 2119.3 2287.84 2538.3 2417.9 3177.1 1891.49 756.78 3435.8 2502.6 TRUE FALSE FALSE 2538.688456 2302.482849 2372.629363 2527.797187 2389.068122 2518.133647 1944.560119 987.5187382 3058.901336 2589.565164 0.980353185 0.889138795 0.916226939 0.976147356 0.922575016 0.972415633 0.750921485 0.38134539 1.181241306 1 11.33849415 -4.293700719 1.765234899 0.972897671 0.203173622 0.854122262 0.076256565 0.128800245 0.415153062 0.006237009 0.161745434 5.09E-05 4.293700719 -0.76972405 down PAS(ph)PVAGSPK ddPTM_HeLa_Curcumin_4h_R1 2 PASPVAGSPK 10 0 Q13057-2;K7EN91;Q13057 Q13057-2 COASY Bifunctional coenzyme A synthase;Phosphopantetheine adenylyltransferase;Dephospho-CoA kinase 1 0 PAS(1)PVAGSPK;PAS(1)PVAGSPK ; 132.17 0.0026126 23334900 12529.8 11377.5 11452.3 12147.9 11239.2 7532.9 7057 6827.3 9449.7 10103.3 TRUE FALSE FALSE 11538.05311 12360.9204 11876.73231 12097.63521 11105.17988 5970.491627 7255.000427 8908.912341 8413.091552 10454.38892 1.103656387 1.182366611 1.136052274 1.157182433 1.062250502 0.571099054 0.693966953 0.852169592 0.804742545 1 13.35182112 -5.276508445 24.17532753 1.076057167 0.704567393 0.654460591 0.118972124 167.0463972 267992.8111 0.013176368 0.029583802 5.29E-06 5.276508445 -0.371489774 PASVDGSPVS(ph)PSTNR ddPTM_HeLa_Curcumin_4h_R1 1 PASVDGSPVSPSTNR 15 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 0 PASVDGS(0.112)PVS(0.665)PS(0.112)T(0.112)NR 93.716 0.0061155 9244100 1782.6 1637.4 1451 1905.6 1822 1689.3 1349.1 1002.5 1762.8 1737 TRUE FALSE FALSE 1641.505329 1778.92956 1504.775336 1897.715132 1800.27384 1338.920138 1386.952115 1308.157635 1569.42525 1797.360621 0.913286577 0.989745485 0.837213923 1.055834378 1.001620832 0.744936838 0.771660455 0.727821462 0.873183285 1 10.81166418 -5.255601417 24.96502064 0.961061463 0.750491655 0.690405192 0.062691382 180.8638213 773429.6057 0.008228732 0.020363754 5.55E-06 5.255601417 -0.210569808 SSS(ph)EITLSECDAEDAGEPR ddPTM_HeLa_Curcumin_4h_R1 2 SSSEITLSECDAEDAGEPR 19 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 0 SS(0.001)S(0.999)EITLSECDAEDAGEPR;S(0.207)S(0.053)S(0.739)EITLSECDAEDAGEPR ; 373.79 4.16E-226 43290000 2246.93 1900.98 1822 2203.96 1875.66 2450.39 1419.77 432.646 2377.11 2140.66 TRUE FALSE FALSE 2069.08312 2065.292241 1889.524923 2194.840597 1853.29398 1942.151492 1459.604925 564.5577737 2116.34698 2215.047776 0.934103157 0.932391736 0.853040257 0.990877317 0.836683524 0.876798918 0.658949636 0.254873859 0.955440783 1 11.1131221 -4.292808941 1.27938921 0.952590439 3.91E-20 0.944312077 0.050316273 0.218800972 0.31342275 0.007992138 0.268174888 5.10E-05 4.292808941 -0.952590439 down PATEKDLAEDAPWK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 PATEKDLAEDAPWKK 15 2 Q60FE5;A0A087WWY3 Q60FE5 FLNA 0 1 PATEKDLAEDAPWK(1)K 78.615 0.0072586 1979000 587.39 645.06 415.85 513.79 636.77 966.47 562.89 618.94 1221.4 638.28 FALSE TRUE FALSE 540.8974617 700.8161121 431.2617668 511.6640731 629.1769336 766.0132276 578.6831785 807.6519568 1087.415476 660.4601825 0.818970584 1.061102744 0.652971637 0.774708433 0.952634164 1.159817424 0.87618178 1.22286245 1.646451224 1 9.367327777 -5.511147468 23.03514055 0.892984717 1.063768256 0 0.274631837 221.3348468 434603.2363 0.020077923 0.042661066 3.08E-06 5.511147468 0.170783539 PATPAEDDEDDDIDLFGS(ph)DNEEEDKEAAQLREER ddPTM_HeLa_Curcumin_4h_R1 2 PATPAEDDEDDDIDLFGSDNEEEDKEAAQLREER 34 2 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;P29692-4;E9PQZ1;H0YE72 P29692 EEF1D Elongation factor 1-delta 1 0 PATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLREER;PATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLREER ; 58.498 0.000223 46242000 2487.18 2076.44 2549.76 2379.88 1698.29 2186.63 1832.6 1937.86 2254.25 2432.69 TRUE FALSE FALSE 2290.317079 2255.918221 2644.256349 2370.032687 1678.039001 1733.09829 1884.017824 2528.704593 2006.964415 2517.225796 0.909857623 0.896192238 1.050464504 0.941525663 0.66662236 0.688495363 0.74845007 1.004560098 0.797292169 1 11.29761892 -5.851056286 7.914375296 0.958621336 0.769072292 0.318228009 0.107445224 0.159722029 12.33155706 0.014077947 0.02561568 1.41E-06 5.851056286 -0.189549043 PCS(ph)EETPAISPS(ph)KR ddPTM_HeLa_Curcumin_4h_R1 2 PCSEETPAISPSKR 14 1 P33316-2;H0YNJ9 P33316-2 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 2 0 PCS(0.996)EET(0.005)PAIS(0.497)PS(0.502)KR;PCS(0.923)EET(0.084)PAIS(0.132)PS(0.862)KR ; 90.765 0.0038261 88985000 18948.8 16232.5 16789.1 17897.1 15486.5 17679.2 15612.4 13020.3 17469.1 18501.5 TRUE FALSE FALSE 17448.98249 17635.56497 17411.31882 17823.04654 15301.8336 14012.33463 16050.44193 16990.12953 15552.78344 19144.42575 0.911439325 0.921185373 0.909471981 0.930978384 0.799284022 0.731927654 0.838387222 0.887471359 0.812392267 1 14.22463677 -6.972820949 0.311704786 1.00327579 0.793839669 0 0.074264076 0.843620406 0.238418217 0.045348808 0.067576888 1.06E-07 6.972820949 -0.20943612 PCSEETPAIS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 PCSEETPAISPSK 13 0 P33316-2;H0YNJ9 P33316-2 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 1 0 PCSEET(0.008)PAIS(0.914)PS(0.078)K;PCSEET(0.001)PAIS(0.995)PS(0.003)K ; 164.92 0.00017661 487149200 10526 8080 9866.8 10148.5 8788.5 8985.7 8480.1 6929.9 8620.7 9719.5 TRUE FALSE FALSE 9692.855993 8778.399196 10232.47229 10106.5082 8683.702877 7121.96453 8718.028783 9042.794609 7675.030778 10057.2519 0.963767845 0.872842729 1.017422293 1.00489759 0.863427004 0.708142204 0.866840054 0.899131761 0.763133991 1 13.29594853 -5.647689304 5.003018716 0.977393479 0.822710726 0.167441879 0.090056095 0.109641477 4.368326629 0.008654566 0.017574335 2.25E-06 5.647689304 -0.154682754 PCSEETPAIS(ph)PSKR ddPTM_HeLa_Curcumin_4h_R1 2 PCSEETPAISPSKR 14 1 P33316-2;H0YNJ9 P33316-2 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 1 0 PCSEETPAIS(0.577)PS(0.423)KR;PCSEET(0.013)PAIS(0.681)PS(0.307)KR ; 153.48 0.00068167 6808371000 9473.5 6759.6 6999.6 7581.5 6035.8 7061.6 6138 5489.7 7664.8 8180.1 TRUE FALSE FALSE 8723.662479 7343.869704 7259.011333 7550.129762 5963.827027 5596.944559 6310.21576 7163.484259 6823.990616 8464.357866 1.030634883 0.86762278 0.857597404 0.891990849 0.704581153 0.661236759 0.745504368 0.846311601 0.80620299 1 13.04718491 -6.612989932 0.970092127 1.016007247 0.741808137 0.35052574 0.090501421 0.173408103 0.32618136 0.012327638 0.021139354 2.44E-07 6.612989932 -0.27419911 PCSEETPAISPS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 PCSEETPAISPSK 13 0 P33316-2;H0YNJ9 P33316-2 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 1 0 PCSEET(0.029)PAIS(0.315)PS(0.657)K 132.97 0.0014538 8902600 2265 1848.2 2148.4 2351.7 1695.2 2375.6 1755.5 1444.5 1941.9 1872.1 TRUE FALSE FALSE 2085.72286 2007.950173 2228.021594 2341.969289 1674.985847 1882.873781 1804.754605 1884.9214 1728.878428 1937.155336 1.076693656 1.036545772 1.150151231 1.208973408 0.86466264 0.971978729 0.931651981 0.973035753 0.892483115 1 10.91972393 -5.734115326 24.99998985 1.057379111 0.937687032 0.347833652 0.084066738 178.0325529 162888.9429 0.010610822 0.021217459 1.84E-06 5.734115326 -0.119692079 PCSEETPAISPS(ph)KR ddPTM_HeLa_Curcumin_4h_R1 1 PCSEETPAISPSKR 14 1 P33316-2;H0YNJ9 P33316-2 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 1 0 PCSEETPAIS(0.221)PS(0.779)KR 67.994 0.016891 26249000 2973 2293.1 2695.7 2589.7 2403.9 2454.2 1635.6 1480.4 2556.3 2122.4 TRUE FALSE FALSE 2737.683913 2491.305346 2795.605013 2578.984508 2375.235063 1945.171255 1681.490534 1931.767145 2275.880286 2196.153242 1.246581459 1.134395041 1.272955348 1.174319013 1.081543408 0.885717453 0.765652643 0.879614003 1.036303042 1 11.10076301 -5.252556458 2.892254255 1.137095876 0.822518903 0.72934032 0.082494389 0.132636437 2.219543911 0.015392502 0.042160587 5.59E-06 5.252556458 -0.314576973 PCSEETPAISPSK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 PCSEETPAISPSKR 14 1 P33316-2;H0YNJ9 P33316-2 DUT "Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial" 0 1 ; PCSEETPAISPSK(1)R;PCSEETPAISPSK(1)R 244.71 3.53E-49 17602200 2975.6 2998.6 2773.5 2812.1 1900.06 3403.7 2615.6 1981.05 2402 2534.3 FALSE TRUE FALSE 2740.07812 3257.785622 2876.28835 2800.464275 1877.403025 2697.734252 2688.986696 2585.063025 2138.50661 2622.366736 1.044887461 1.242307408 1.096829177 1.06791481 0.715919326 1.028740265 1.025404517 0.985774792 0.815487239 1 11.35665374 PDDITIDVTINESISHS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 PDDITIDVTINESISHSR 18 0 H7C3W4;C9J9W1;Q9NPH3-2;Q9NPH3;Q9NPH3-5 H7C3W4 IL1RAP Interleukin-1 receptor accessory protein 1 0 PDDIT(0.005)IDVT(0.007)INES(0.006)IS(0.038)HS(0.944)R 71.153 0.013322 11680000 2096.2 2332.3 2529.3 2596.9 2207.2 2157.9 1891.6 2639.3 3559.4 2871.2 TRUE FALSE FALSE 1930.283558 2533.893619 2623.038083 2586.154716 2180.880582 1710.327215 1944.673205 3444.01042 3168.942725 2970.973986 0.649714056 0.852883139 0.88288827 0.870473699 0.734062497 0.57567896 0.654557466 1.159219312 1.066634289 1 11.53672026 -9.560630802 1.331973051 1.00008278 0.772282906 0.239762261 0.159174614 0.541837566 1.721684778 0.110746012 0.026047031 2.75E-10 9.560630802 -0.227799874 PDPAGHLT(ph)LRDNRLK ddPTM_HeLa_Curcumin_4h_R1 2 PDPAGHLTLRDNRLK 15 2 Q9NTJ4-3;Q9NTJ4-2;Q9NTJ4;Q9NTJ4-4 Q9NTJ4-3 MAN2C1 Alpha-mannosidase 2C1 1 0 PDPAGHLT(1)LRDNRLK;PDPAGHLT(1)LRDNRLK ; 100.19 0.0016895 52677000 21556.3 18487.9 19535.9 18286.5 18768.2 29306 21646.5 21075.2 21399.6 19773.9 TRUE FALSE FALSE 19850.09611 20085.9117 20259.91764 18210.83531 18544.40147 23227.60525 22253.84253 27500.93146 19052.11742 20461.04155 0.970141039 0.981666141 0.990170397 0.890024844 0.906327345 1.135211284 1.087620221 1.344063126 0.931141133 1 14.32059197 -4.084159851 1.097380499 0.976086866 1.622383339 0.811232914 0.055925161 0.733207193 0.546783794 0.008148041 0.599122783 8.24E-05 4.084159851 0.646296473 PDPAK(ac)SAPAPK ddPTM_HeLa_Curcumin_4h_R1 2 PDPAKSAPAPK 11 1 Q5QNW6;Q5QNW6-2;Q93079 Q5QNW6;Q93079 HIST2H2BF;HIST1H2BH Histone H2B type 2-F;Histone H2B type 1-H 0 1 ; PDPAK(1)SAPAPK;PDPAK(1)SAPAPK 150.09 6.18E-06 527630000 19507.1 14100.1 15026.6 15942.5 14796.1 16428.7 15112 9638.6 15178.1 13868.9 FALSE TRUE FALSE 17963.09245 15318.84982 15583.49901 15876.53416 14619.66617 13021.20243 15536.00205 12577.36477 13513.1004 14350.84324 1.251709892 1.06745294 1.08589431 1.106313677 1.018732204 0.907347548 1.082584611 0.876419912 0.941624138 1 13.80884789 -5.655473625 3.14292634 1.11431082 0.966946585 0.177442966 0.094945859 0.243629533 4.790485416 0.015280324 0.032439871 2.21E-06 5.655473625 -0.147364234 PDPAK(ac)SAPAPK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 PDPAKSAPAPKK 12 2 Q5QNW6;Q5QNW6-2;Q93079 Q5QNW6;Q93079 HIST2H2BF;HIST1H2BH Histone H2B type 2-F;Histone H2B type 1-H 0 2 PDPAK(1)SAPAPK(1)K 116.54 0.0039954 3045700 1573 1210.1 1377.1 1353.5 1452.5 1395.7 1215.5 1417.7 1350.2 1135.1 FALSE TRUE FALSE 1448.49539 1314.695652 1428.136537 1347.899576 1435.179886 1106.216087 1249.603659 1849.950204 1202.086438 1174.544641 1.233239964 1.119323699 1.215906563 1.147593313 1.221903227 0.941825495 1.063904781 1.575036095 1.023448915 1 10.19788583 -9.404568081 1.029490652 0.995686604 1.180311558 0.173587042 0.154041915 0.814244479 1.484808183 0.113700029 0.026303202 3.94E-10 9.404568081 0.184624953 PDPAK(ac)SAPAPK(ac)K(ac)GSK ddPTM_HeLa_Curcumin_4h_R1 2 PDPAKSAPAPKKGSK 15 3 Q5QNW6;Q5QNW6-2;Q93079 Q5QNW6;Q93079 HIST2H2BF;HIST1H2BH Histone H2B type 2-F;Histone H2B type 1-H 0 3 ; PDPAK(1)SAPAPK(1)K(1)GSK;PDPAK(1)SAPAPK(1)K(1)GSK 191.19 3.11E-24 3350800 2652.25 1707.81 2049.66 2127.5 1787.85 2114.66 2355.88 3065.83 1966.38 2302.63 FALSE TRUE FALSE 2442.321614 1855.425487 2125.622203 2118.696969 1766.531056 1676.055679 2421.979652 4000.587454 1750.673034 2382.646221 1.025045847 0.77872471 0.892126655 0.889220124 0.741415591 0.703442947 1.016508297 1.679052231 0.734759956 1 11.21834904 -4.271188838 4.488660625 0.939939904 1.722891954 0.753944138 0.134107067 0.076250636 3.838841526 0.019543877 0.185295594 5.36E-05 4.271188838 0.78295205 PDPSK(ac)SAPAPK ddPTM_HeLa_Curcumin_4h_R1 2 PDPSKSAPAPK 11 1 Q8N257 Q8N257 HIST3H2BB Histone H2B type 3-B 0 1 ; PDPSK(1)SAPAPK;PDPSK(1)SAPAPK 111.86 0.0039178 9590000 7202.6 5254.3 5776.2 6994.3 6055.7 6348.4 5436.1 3756.4 6149.6 4867.4 FALSE TRUE FALSE 6632.50661 5708.458279 5990.271053 6965.35944 5983.489733 5031.670279 5588.622335 4901.709068 5475.004266 5036.541788 1.316877113 1.133408303 1.189361928 1.382964688 1.188015504 0.999032767 1.109615004 0.973229107 1.087056257 1 12.29821777 -5.267705579 23.39997786 1.174822586 1.035524561 0.310112088 0.107037776 275.110494 1027357.075 0.019898072 0.045607519 5.40E-06 5.267705579 -0.139298025 PDVVDIVAQLQRLEGLR ddPTM_HeLa_Curcumin_4h_R1 1 PDVVDIVAQLQRLEGLR 17 1 Q9NZB8-4;Q9NZB8-3;Q9NZB8-6;Q9NZB8-5;Q9NZB8-7;Q9NZB8-2;Q9NZB8-8;Q9NZB8 Q9NZB8-4 MOCS1 Molybdenum cofactor biosynthesis protein 1;Cyclic pyranopterin monophosphate synthase;Cyclic pyranopterin monophosphate synthase accessory protein 0 0 35.659 0.01797 1208800 1287.2 1258.1 992.89 1139.2 1304.8 1727.5 1268.4 357.63 1490.2 1054.5 FALSE FALSE TRUE 1185.316762 1366.844558 1029.687377 1134.486292 1289.241112 1369.197027 1303.98789 466.6697407 1326.728788 1091.143797 1.08630665 1.252671337 0.943677066 1.039722075 1.181550146 1.254827303 1.195065118 0.42768858 1.215906458 1 10.09162552 -4.255246143 24.87686139 1.080475114 0.427688268 0.766332066 0.113412391 250.4835899 1006107.098 0.015798284 0.196111345 5.56E-05 4.255246143 -0.652786846 PEANYLLS(ph)VS(ph)WGY(ph)IK ddPTM_HeLa_Curcumin_4h_R1 1 PEANYLLSVSWGYIK 15 0 Q08499-8;Q07343-4 Q08499-8 PDE4D;PDE4B "cAMP-specific 3,5-cyclic phosphodiesterase 4D;cAMP-specific 3,5-cyclic phosphodiesterase 4B" 3 0 PEANY(0.002)LLS(0.998)VS(1)WGY(1)IK 56.121 0.0090533 0 70.971 259.5 176.74 242.55 189.97 311.65 389.43 314.48 409.98 208.2 TRUE FALSE FALSE 65.35357046 281.9300237 183.2901399 241.5463924 187.7047318 247.010277 400.3563577 410.3635043 365.0062197 215.4349345 0.30335642 1.30865509 0.850791169 1.121203453 0.871282702 1.146565563 1.858363216 1.904814116 1.69427591 1 7.751108403 -4.370759947 0.609116756 0.718822043 2.772557767 0.256984961 0.410597592 1.484904056 0.405137636 0.061589269 2.072908157 4.26E-05 4.370759947 2.053735724 PEAPESK(ac)PAPK ddPTM_HeLa_Curcumin_4h_R1 1 PEAPESKPAPK 11 1 Q7Z7G0-4 Q7Z7G0-4 0 1 PEAPESK(1)PAPK 93.058 0.017247 4885200 1962.8 1392.3 1469.4 1923.5 1497.5 1616.3 1686.6 1210.8 1705.5 1711.7 FALSE TRUE FALSE 1807.442309 1512.644208 1523.857257 1915.541067 1479.643291 1281.061161 1733.921457 1579.967346 1518.410917 1771.181448 1.020472697 0.854031195 0.860362025 1.081504704 0.835399045 0.723280589 0.978963199 0.892041495 0.857287049 1 10.7904963 -7.26924166 24.50526027 1.009667666 0.890625243 0.025290903 0.100488701 431.8182217 1356244.078 0.014893638 0.017203333 5.38E-08 7.26924166 -0.119042423 PEILSFFSTNLQR ddPTM_HeLa_Curcumin_4h_R1 1 PEILSFFSTNLQR 13 0 Q8N201;H7C582 Q8N201 INTS1 Integrator complex subunit 1 0 0 104.42 0.0035854 9061800 0 0 0 0 0 0 54.272 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 55.79472625 0 0 0 0 PEK(ac)DQLKNK(ac)FMK ddPTM_HeLa_Curcumin_4h_R1 1 PEKDQLKNKFMK 12 3 Q9Y6R1-3;Q9Y6R1-4;Q9Y6R1-2;Q9Y6R1;Q9Y6R1-5 Q9Y6R1-3 SLC4A4 Electrogenic sodium bicarbonate cotransporter 1 0 2 PEK(1)DQLKNK(1)FMK 128.91 0.00047697 2333400 1033.4 975.03 902.13 795.09 816.87 1082.6 1003.2 1077.2 918.27 999.2 FALSE TRUE FALSE 951.6052996 1059.307249 935.5637314 791.8001283 807.1293588 858.0565566 1031.347092 1405.633321 817.5380784 1033.922126 0.920383921 1.024552258 0.904868663 0.765821824 0.780648115 0.829904434 0.997509451 1.35951566 0.790715334 1 10.01391181 -4.281465983 3.661474431 0.927485462 1.398406506 0.674763398 0.095724485 0.123919425 3.052222946 0.013864315 0.15348724 5.23E-05 4.281465983 0.470921044 PELAK(ac)SAPAPK ddPTM_HeLa_Curcumin_4h_R1 2 PELAKSAPAPK 11 1 Q99880 Q99880 HIST1H2BL Histone H2B type 1-L 0 1 ; PELAK(1)SAPAPK;PELAK(1)SAPAPK 189.57 4.49E-16 64368000 12762.2 8828 10185.3 10514 9761 11792.1 11549 6989.5 10145.9 9553.9 FALSE TRUE FALSE 11752.0584 9591.052983 10562.77618 10470.49585 9644.60645 9346.285536 11873.03386 9120.566374 9032.920154 9885.897314 1.188770026 0.970175259 1.068469138 1.059134596 0.975592417 0.945416004 1.201007201 0.922583564 0.913717781 1 13.27115621 -7.231688501 24.95601859 1.089141429 1.026029004 0 0.102480701 1353.393145 1135272.206 0.016117967 0.019739552 5.87E-08 7.231688501 -0.063112425 PEPAK(ac)SAPAPK ddPTM_HeLa_Curcumin_4h_R1 3 PEPAKSAPAPK 11 1 P62807;P57053;O60814;Q16778;P06899 P62807;Q16778 HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J 0 1 ;; PEPAK(1)SAPAPK;PEPAK(1)SAPAPK;PEPAK(1)SAPAPK 152.54 6.92E-07 3036314700 11787.5 23105 8958.5 12689.6 9526.5 10172.2 10304.3 6280.1 10405.9 10399 FALSE TRUE FALSE 10854.50694 25102.09325 9290.509891 12637.0938 9412.902709 8062.371056 10593.41093 8194.87358 9264.398804 10760.36448 1.008749003 2.332829274 0.863401041 1.174411315 0.874775453 0.74926561 0.984484396 0.761579554 0.860974442 1 13.39343933 -5.704359459 6.379296243 1.11380044 0.843097914 0.137344566 0.409436716 0.41681083 34.5237929 0.059552496 0.119229805 1.98E-06 5.704359459 -0.270702527 PEPAK(ac)SAPAPK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 PEPAKSAPAPKK 12 2 P62807;P57053;O60814;Q16778;P06899 P62807;Q16778 HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J 0 2 ; PEPAK(1)SAPAPK(1)K;PEPAK(1)SAPAPK(1)K 174.57 7.13E-09 29993000 13313.4 10257.6 12155.3 12423.3 11869.4 11973.9 12023 10111.2 10648.8 9591.7 FALSE TRUE FALSE 12259.63034 11144.22124 12605.78611 12371.89568 11727.86516 9490.378166 12360.33302 13194.05833 9480.653282 9925.010861 1.235225887 1.122842221 1.270103004 1.246537243 1.181647589 0.956208341 1.245372241 1.3293747 0.955228505 1 13.27685297 -9.340512626 0.901835312 0.991456071 1.195898198 0.441738158 0.097941335 0.579265343 0.785994305 0.08260738 0.018393599 4.57E-10 9.340512626 0.204442127 PEPAK(ac)SAPAPK(ac)K(ac)GSK ddPTM_HeLa_Curcumin_4h_R1 1 PEPAKSAPAPKKGSK 15 3 P62807;P57053;O60814;Q16778;P06899 P62807;Q16778 HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J 0 3 PEPAK(1)SAPAPK(1)K(1)GSK 221.59 1.16E-35 24988000 7180.4 5785.7 5642.9 6853.7 4988.6 5898.5 6931.5 8654.7 6369.6 6072.5 FALSE TRUE FALSE 6612.063763 6285.790127 5852.030838 6825.341205 4929.114203 4675.08461 7125.979235 11293.47819 5670.870816 6283.518923 1.052286759 1.000361454 0.931330185 1.086229116 0.784451239 0.74402332 1.134074604 1.797317447 0.902499202 1 12.61735701 -4.289420849 3.690499797 0.987765622 1.862726063 0.833990907 0.113160106 0.073733573 1.848535794 0.016101419 0.167834003 5.14E-05 4.289420849 0.874960441 PEPAK(ac)SAPAPK(ac)KGSK ddPTM_HeLa_Curcumin_4h_R1 2 PEPAKSAPAPKKGSK 15 3 P62807;P57053;O60814;Q16778;P06899 P62807;Q16778 HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J 0 2 ; PEPAK(1)SAPAPK(0.921)K(0.079)GSK;PEPAK(1)SAPAPK(0.71)K(0.29)GSK 127.3 0.00030531 17532800 13401.8 7947.3 9724.3 9878.3 7617 10145.2 7660.4 6780.4 11918.1 10515.3 FALSE TRUE FALSE 12341.03339 8634.2292 10084.69111 9837.426212 7526.17225 8040.97116 7875.330207 8847.712747 10610.71425 10880.70589 1.13421257 0.793535758 0.926841623 0.904116544 0.691698896 0.739011902 0.723788538 0.813156135 0.975186201 1 13.40948453 -6.632521941 1.003763969 1.060008228 0.749195741 0.585416427 0.086762198 0.213162694 0.429333564 0.01758143 0.029538459 2.33E-07 6.632521941 -0.310812486 PEPSK(ac)SAPAPK ddPTM_HeLa_Curcumin_4h_R1 2 PEPSKSAPAPK 11 1 P33778;U3KQK0;Q99877 P33778;U3KQK0 HIST1H2BB;HIST1H2BN Histone H2B type 1-B;Histone H2B;Histone H2B type 1-N 0 1 ; PEPSK(1)SAPAPK;PEPSK(1)SAPAPK 177.44 1.58E-11 252380000 13797.4 10280.4 12492.6 11759.9 10251 12065.4 11899 7112.4 11394.2 10273 FALSE TRUE FALSE 12705.32123 11168.99197 12955.58675 11711.24065 10128.76352 9562.900035 12232.85392 9280.938019 10144.28477 10629.98599 1.195234053 1.05070618 1.218777406 1.101717412 0.952848248 0.899615488 1.150787398 0.873090334 0.954308386 1 13.37585207 -5.768621693 24.09185659 1.102027088 0.977101944 0.231744525 0.102352284 111.0262551 372421.3089 0.01502612 0.027673145 1.70E-06 5.768621693 -0.124925144 PEPTK(ac)SAPAPK ddPTM_HeLa_Curcumin_4h_R1 3 PEPTKSAPAPK 11 1 P58876 P58876 HIST1H2BD Histone H2B type 1-D 0 1 ;; PEPTK(1)SAPAPK;PEPTK(1)SAPAPK;PEPTK(1)SAPAPK 169.21 1.89E-11 751490000 15344.85 15155.5 13080.14 14363.9 11837.82 13227.78 13835.35 8167.48 12684.95 10660.48 FALSE TRUE FALSE 14130.28893 16465.47389 13564.90149 14304.46599 11696.66173 10484.18932 14223.53269 10657.70705 11293.44272 11030.93089 1.280969764 1.492664042 1.229715029 1.296759642 1.060351284 0.950435591 1.2894227 0.966165699 1.023797795 1 13.42926692 -4.234621272 22.76128698 1.167423764 0.966164784 0.132149688 0.161670398 4765.733239 4044596.054 0.024552605 2.241954652 5.83E-05 4.234621272 -0.201258979 PEPTK(ac)SAPAPK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 PEPTKSAPAPKK 12 2 P58876 P58876 HIST1H2BD Histone H2B type 1-D 0 2 ; PEPTK(1)SAPAPK(1)K;PEPTK(1)SAPAPK(1)K 196.24 3.85E-15 6745300 4323.8 3471.4 4026.5 4025.3 4078.4 4532.7 4137.1 3462 3167 3470.9 FALSE TRUE FALSE 3981.566668 3771.452348 4175.725632 4008.644375 4029.767744 3592.566926 4253.175892 4517.547863 2819.588023 3591.513517 1.108604116 1.050101115 1.162664602 1.116143474 1.122024942 1.000293305 1.184229399 1.257839583 0.785069584 1 11.81037623 -1.122762502 0.016913089 2.98E-08 2.474070836 0.430504392 0.093597461 2674.903639 3.595893706 205.960264 334.8236583 0.075376766 1.122762502 2.474070806 PEPTK(ac)SAPAPK(ac)K(ac)GSK ddPTM_HeLa_Curcumin_4h_R1 2 PEPTKSAPAPKKGSK 15 3 P58876 P58876 HIST1H2BD Histone H2B type 1-D 0 3 ; PEPTK(1)SAPAPK(1)K(1)GSK;PEPTK(1)SAPAPK(1)K(1)GSK 176.43 7.03E-07 19360000 7592.5 5419.5 6093.2 6730.1 6020.2 7579.2 6832.6 8334.6 6995.6 6720 FALSE TRUE FALSE 6991.545613 5887.937431 6319.019352 6702.252629 5948.413047 6007.188485 7024.304367 10875.78117 6228.200182 6953.5195 1.005468614 0.846756442 0.908751223 0.963864792 0.855453565 0.863906182 1.010179718 1.564068552 0.895690331 1 12.76352766 -4.26524603 4.589291643 0.963276196 1.600212017 0.885632263 0.067719491 0.051106825 2.816073401 0.010591645 0.103985196 5.43E-05 4.26524603 0.636935821 PEPVK(ac)SAPVPK ddPTM_HeLa_Curcumin_4h_R1 2 PEPVKSAPVPK 11 1 Q99879 Q99879 HIST1H2BM Histone H2B type 1-M 0 1 ; PEPVK(1)SAPVPK;PEPVK(1)SAPVPK 147.3 1.24E-05 42086000 10864 7944.1 8448.3 8594.7 7798.1 8753.8 8744.4 6080.5 8085.1 7527.3 FALSE TRUE FALSE 10004.10294 8630.752606 8761.40143 8559.137409 7705.112751 6938.163204 8989.74433 7934.416459 7198.184758 7788.873115 1.28440954 1.108087457 1.124861235 1.098892906 0.989246151 0.89077882 1.154177786 1.018686059 0.92416254 1 12.9271989 -5.916505026 4.14195635 1.134006308 1.01503223 0.029365813 0.109998438 0.299404031 9.806503319 0.017839718 0.033140885 1.21E-06 5.916505026 -0.118974078 PFS(ph)GTTPSR ddPTM_HeLa_Curcumin_4h_R1 1 PFSGTTPSR 9 0 A0A1B0GTR0 A0A1B0GTR0 1 0 PFS(0.333)GT(0.333)T(0.333)PSR 99.375 0.013497 226030000 6458 5066.8 5782.2 5269.7 5388.1 6502.7 5977.9 5551.7 6119 5792.2 TRUE FALSE FALSE 5946.842486 5504.751615 5996.493419 5247.895378 5323.850427 5153.966719 6145.623785 7244.387773 5447.761009 5993.478519 0.99221887 0.918456886 1.00050303 0.875600932 0.888273881 0.859929122 1.025385136 1.208711727 0.908948116 1 12.54917785 -4.316704497 3.651174708 0.966792169 1.222886628 0.636396686 0.059209287 0.132857574 3.078663131 0.008960821 0.082723711 4.82E-05 4.316704497 0.256094458 PFVT(ph)ICT(ph)NS(ph)ILT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 PFVTICTNSILTK 13 0 Q5SVZ7;Q5SVZ6 Q5SVZ7 ZMYM1 Zinc finger MYM-type protein 1 4 0 PFVT(1)ICT(1)NS(1)ILT(1)K 79.337 0.011483 4361700 289.97 145.11 315 247.22 364.7 334.28 334.37 197.82 306.01 245.41 TRUE FALSE FALSE 267.0185685 157.6526618 326.6741771 246.1970691 360.3511907 264.9465599 343.7515223 258.1344073 272.4414686 253.9379792 1.051510961 0.620831363 1.286432924 0.969516533 1.419051974 1.043351454 1.353682987 1.016525406 1.072866176 1 7.988332372 PGAGQPGEFHT(ph)TPPGTPR ddPTM_HeLa_Curcumin_4h_R1 1 PGAGQPGEFHTTPPGTPR 18 0 O14686;O14686-3 O14686 KMT2D Histone-lysine N-methyltransferase 2D 1 0 PGAGQPGEFHT(0.5)T(0.5)PPGT(0.001)PR 73.346 0.010831 5356800 2609.6 1719.1 2080.4 2347.3 2444 2309.2 1751.2 1070.4 2003.6 1982.7 TRUE FALSE FALSE 2403.047406 1867.691344 2157.501454 2337.587495 2414.856896 1830.24589 1800.333959 1396.760032 1783.810093 2051.598677 1.171304814 0.910359011 1.051619636 1.139398032 1.177061051 0.89210717 0.877527354 0.680815428 0.869473212 1 11.00253283 -4.69343281 1.568075538 1.076154984 0.687082891 0.497377545 0.107770799 0.259027241 1.001684771 0.013997714 0.120267635 2.03E-05 4.69343281 -0.389072093 PGHLQEGFGCVVTNR ddPTM_HeLa_Curcumin_4h_R1 2 PGHLQEGFGCVVTNR 15 0 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 0 ; ; 123.72 0.00029824 7805800 6128.6 5715.8 5623.1 5870 5873.9 5211.2 4984.6 4650.2 5448.4 5557.4 FALSE FALSE TRUE 5643.514843 6209.848283 5831.497033 5845.711495 5803.857579 4130.338378 5124.454461 6068.024573 4850.724151 5750.519236 0.981392221 1.079876099 1.014081823 1.016553681 1.009275396 0.718254858 0.891129001 1.055213334 0.843528028 1 12.48947651 SQANGAGALSYVS(ph)PNTSK ddPTM_HeLa_Curcumin_4h_R1 2 SQANGAGALSYVSPNTSK 18 0 O95453;O95453-3;O95453-2;A0A494C0W0;A0A494C0K5;A0A494C0Q6;A0A494C002;A0A494C1N1;A0A494C0Q2;F5H1Z4;A0A494C1K5;A0A494C0P9;A0A494BZU6;A0A494C1G3;A0A494C156;A0A494BZW7 O95453 PARN Poly(A)-specific ribonuclease PARN 1 0 SQANGAGALSYVS(0.761)PNT(0.239)SK;SQANGAGALS(0.005)YVS(0.833)PNT(0.152)S(0.009)K ; 193.54 5.17E-09 41953000 11174.7 10010.3 11132.6 10775.2 9808.7 11467.8 7349.3 3444.6 11170.5 9122.7 TRUE FALSE FALSE 10290.2107 10875.54573 11545.18395 10730.61508 9691.737659 9089.249011 7555.501578 4494.842683 9945.124097 9439.713146 1.090097818 1.152105531 1.223043939 1.136752241 1.026698323 0.962873434 0.800395252 0.476163059 1.053540923 1 13.2045273 -4.29226963 1.242003674 1.072571074 0.226414757 0.901364821 0.064232855 0.386449919 0.51446664 0.012022984 0.411268678 5.10E-05 4.29226963 -0.846156317 down PGPGPPS(ph)VGS(ph)ARS(ph)S(ph)VS(ph)SLGSR ddPTM_HeLa_Curcumin_4h_R1 1 PGPGPPSVGSARSSVSSLGSR 21 1 A6NIX2 A6NIX2 WTIP Wilms tumor protein 1-interacting protein 5 0 PGPGPPS(1)VGS(0.999)ARS(0.97)S(0.943)VS(0.538)S(0.479)LGS(0.07)R 41.296 0.0091985 0 927.45 781.68 925.76 794.38 885.4 1069.4 692.22 591.54 929.58 752.93 TRUE FALSE FALSE 854.0413539 849.2449361 960.06948 791.093066 874.8421833 847.5943854 711.6418302 771.8978229 827.6073997 779.0942615 1.096197721 1.090041319 1.232289246 1.015400966 1.122896454 1.087922768 0.913421989 0.990763071 1.062268638 1 9.605654078 -4.767248225 24.9892381 1.068532847 0.952092521 0.387884827 0.064749758 117.0808402 503683.9831 0.010036224 0.031340572 1.71E-05 4.767248225 -0.116440326 PGPTPSGTNVGS(ph)SGRSPSKAVAAR ddPTM_HeLa_Curcumin_4h_R1 1 PGPTPSGTNVGSSGRSPSKAVAAR 24 2 P60468 P60468 SEC61B Protein transport protein Sec61 subunit beta 1 0 PGPTPS(0.001)GT(0.001)NVGS(0.416)S(0.144)GRS(0.416)PS(0.023)KAVAAR 50.255 0.006886 13095000 1788 1085.3 1072.1 1782.5 693.5 1314.4 961.92 796.44 3408.9 3294.9 TRUE FALSE FALSE 1646.477913 1179.108496 1111.832969 1775.124487 685.2304654 1041.778624 988.9088863 1039.27089 3034.952199 3409.39753 0.482923419 0.34584072 0.32610834 0.520656354 0.20098286 0.305560913 0.290053852 0.304825378 0.890172581 1 11.73530111 -8.894440195 0.386365092 1.157993533 0.275863669 0.902294937 0.080014133 0.350106952 0.084989062 0.128412932 0.029230406 1.28E-09 8.894440195 -0.882129864 PGPTPSGTNVGSS(ph)GRSPSK ddPTM_HeLa_Curcumin_4h_R1 2 PGPTPSGTNVGSSGRSPSK 19 1 P60468 P60468 SEC61B Protein transport protein Sec61 subunit beta 1 0 PGPT(0.002)PS(0.041)GT(0.03)NVGS(0.141)S(0.401)GRS(0.335)PS(0.051)K;PGPTPSGTNVGS(0.065)S(0.629)GRS(0.296)PS(0.01)K ; 83.31 0.0016065 18707300 5314 4697.2 5176.8 6319.5 4728.4 6031.2 4286.1 2647.2 7192.2 6238.6 TRUE FALSE FALSE 4893.391293 5103.205038 5368.656762 6293.351583 4672.016918 4780.261134 4406.356431 3454.319094 6403.233654 6455.390886 0.758031757 0.790533854 0.831654792 0.974898607 0.72373881 0.740506844 0.682585533 0.535106108 0.99192036 1 12.65628874 -8.832568275 0.045510924 1.7777849 2.93E-29 0.630992798 0.086656641 74.98143174 1.102319789 24.77690461 18.30017368 1.47E-09 8.832568275 -1.7777849 PGPTPSGTNVGSSGRS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 4 PGPTPSGTNVGSSGRSPSK 19 1 P60468 P60468 SEC61B Protein transport protein Sec61 subunit beta 1 0 PGPTPSGTNVGS(0.001)S(0.101)GRS(0.891)PS(0.007)K;PGPTPS(0.002)GT(0.084)NVGS(0.062)S(0.079)GRS(0.768)PS(0.004)K;PGPTPSGTNVGSS(0.002)GRS(0.996)PS(0.002)K;PGPTPSGTNVGS(0.002)S(0.011)GRS(0.981)PS(0.006)K ;;; 134.8 8.12E-05 339836000 8177.5 9266.8 7877.8 11746.7 8073.5 9831.6 5208.6 3318.62 12156.2 11071.8 TRUE FALSE FALSE 7530.242246 10067.7809 8169.758198 11698.09527 7977.228785 7792.415335 5354.739298 4330.451961 10822.69527 11456.54423 0.657287407 0.87877991 0.713108424 1.02108411 0.696303233 0.680171541 0.467395682 0.377989372 0.944673635 1 13.48388431 -4.849657944 1.347264184 0.837762998 0.349453764 0.684630986 0.115913988 0.318343256 0.922060246 0.021362232 0.157810713 1.41E-05 4.849657944 -0.488309234 PGPTQTLS(ph)PNGENNNDIIQDNNGTIIPFRK ddPTM_HeLa_Curcumin_4h_R1 1 PGPTQTLSPNGENNNDIIQDNNGTIIPFRK 30 1 Q15555-2;Q15555 Q15555-2 MAPRE2 Microtubule-associated protein RP/EB family member 2 1 0 PGPT(0.024)QT(0.072)LS(0.904)PNGENNNDIIQDNNGTIIPFRK 94.352 3.71E-08 17106000 1256.4 968.28 545.72 737.83 639.13 646.31 518.91 411.12 989.3 818.81 TRUE FALSE FALSE 1156.954614 1051.973809 565.9448633 734.777055 631.5087922 512.2580206 533.469218 536.4685954 880.7762651 847.2635866 1.365519105 1.241613384 0.667967882 0.867235494 0.745351036 0.604602899 0.629637844 0.63317792 1.039554017 1 9.726667056 -6.7591599 24.99998531 1.182604617 0.695033881 0.790826917 0.118298815 25.0325367 274539.6971 0.024950631 0.034325021 1.74E-07 6.7591599 -0.487570736 PGS(ph)LPLNAEACWPK ddPTM_HeLa_Curcumin_4h_R1 2 PGSLPLNAEACWPK 14 0 Q01581;D6RIW1 Q01581 HMGCS1 "Hydroxymethylglutaryl-CoA synthase, cytoplasmic" 1 0 PGS(1)LPLNAEACWPK;PGS(1)LPLNAEACWPK ; 138.91 0.00080057 79498000 5928.6 4649.6 5203.4 5201.1 4621.5 5222.7 4868.7 5417.8 5052.1 5533 TRUE FALSE FALSE 5459.345054 5051.490706 5396.242581 5179.579226 4566.391631 4139.453148 5005.302619 7069.66228 4497.89727 5725.271338 0.953552195 0.882314638 0.942530452 0.904687118 0.79758519 0.723014317 0.874247232 1.234816983 0.785621677 1 12.48312835 -7.62266225 0.967968475 0.988895841 0.893979021 0 0.141316557 0.89506081 1.740788569 0.031076654 0.03045593 2.38E-08 7.62266225 -0.09491682 PGT(ph)CPS(ph)KT(ph)Y(ph)DPLIK ddPTM_HeLa_Curcumin_4h_R1 1 PGTCPSKTYDPLIK 14 1 O95025 O95025 SEMA3D Semaphorin-3D 4 0 PGT(1)CPS(1)KT(1)Y(1)DPLIK 43.405 0.019837 2473100 1182.9 977.01 1220.3 1107.5 1037 1458.8 986.54 822.66 1490.5 1127 TRUE FALSE FALSE 1089.272217 1061.458391 1265.525391 1102.917458 1024.634452 1156.228436 1014.219657 1073.485247 1326.995879 1166.163166 0.934065016 0.910214301 1.085204394 0.945765988 0.878637297 0.99148084 0.869706476 0.920527485 1.137916132 1 10.18755394 -5.99860535 24.99623709 0.972621979 0.916665423 0.197988149 0.074425408 60.12933211 1077643.417 0.00790015 0.014240221 1.00E-06 5.99860535 -0.055956555 PGVT(ph)EATITGLEPGT(ph)EY(ph)T(ph)IYVIALK ddPTM_HeLa_Curcumin_4h_R1 1 PGVTEATITGLEPGTEYTIYVIALK 25 0 H0Y4K8;H0Y7Z1;P02751-13;P02751-7;P02751-1;P02751-11;P02751-3;P02751-17;P02751-8;P02751-14;P02751-9;P02751-5;P02751-6;P02751-10;P02751-4;P02751-12;P02751 H0Y4K8 FN1 Fibronectin;Anastellin;Ugl-Y1;Ugl-Y2;Ugl-Y3 4 0 PGVT(0.769)EAT(0.114)IT(0.125)GLEPGT(0.954)EY(0.683)T(0.692)IY(0.662)VIALK 43.799 0.0072913 0 381.53 245.01 221.08 315.62 332.6 469.19 252.79 198.01 278.42 361.63 TRUE FALSE FALSE 351.3314979 266.1875727 229.2734193 314.3140481 328.6339622 371.8747051 259.8826071 258.3823375 247.8780226 374.1966156 0.938895445 0.71135751 0.612708426 0.839970312 0.878238735 0.993794945 0.694508171 0.690498863 0.662427217 1 8.5476527 -7.395053772 4.846266302 0.973633202 0.780524172 0 0.14314254 0.17366194 6.052533559 0.019370746 0.021975288 4.03E-08 7.395053772 -0.19310903 S(ph)SPVGGGPR ddPTM_HeLa_Curcumin_4h_R1 2 SSPVGGGPR 9 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 0 S(0.933)S(0.067)PVGGGPR;S(0.5)S(0.5)PVGGGPR ; 122.96 0.0054681 278920900 12178.4 14175.3 12178.9 10643.8 13032.8 13564.3 8820.8 1921.1 11193.7 11634.4 TRUE FALSE FALSE 11214.46679 15400.54977 12630.26075 10599.75878 12877.39237 10750.91128 9068.287908 2506.834546 9965.779115 12038.69453 0.931535123 1.279254135 1.049138734 0.880474103 1.069666843 0.893029659 0.753261733 0.208231427 0.827812275 1 13.55539134 -4.291700406 1.736489441 0.995131333 2.70E-20 0.802994553 0.118302964 0.25653652 0.78986466 0.015515752 0.412288476 5.11E-05 4.291700406 -0.995131333 down PIFGGTVYHS(ph)PVSR ddPTM_HeLa_Curcumin_4h_R1 2 PIFGGTVYHSPVSR 14 0 G3V3N7;O43663-3;O43663-2;O43663-4;O43663;H0YNE4 G3V3N7 PRC1 Protein regulator of cytokinesis 1 1 0 PIFGGTVYHS(0.99)PVS(0.01)R;PIFGGTVYHS(0.896)PVS(0.103)R ; 112.3 0.001239 29699000 3080.3 2461.85 2480.2 2574.6 2905.2 3593.4 3432.1 1518.33 2483.9 2255.16 TRUE FALSE FALSE 2836.491005 2674.641344 2572.118394 2563.946987 2870.557387 2848.088334 3528.395489 1981.261827 2211.422384 2333.526642 1.215538299 1.146179905 1.102245137 1.098743396 1.230136968 1.220508171 1.512044228 0.849041872 0.947673939 1 11.18829622 -9.603531996 0.600650069 0.947838055 1.18769786 0.19690529 0.155872902 2.144255382 0.903353535 0.302644969 0.032031884 2.49E-10 9.603531996 0.239859805 PIPNQPPTAAHTANFLLNASGS(ph)TSTPAPSR ddPTM_HeLa_Curcumin_4h_R1 1 PIPNQPPTAAHTANFLLNASGSTSTPAPSR 30 0 P53396;P53396-2;P53396-3;K7EIE7 P53396 ACLY ATP-citrate synthase 1 0 PIPNQPPTAAHTANFLLNAS(0.041)GS(0.243)T(0.243)S(0.243)T(0.169)PAPS(0.059)R 91.466 5.00E-08 12576000 738.09 976.21 1032 916.5 1013.5 1624.6 1025.8 741.37 938.63 760.65 TRUE FALSE FALSE 679.6693977 1060.589242 1070.246828 912.7077658 1001.414674 1287.639647 1054.581187 967.4103002 835.6646373 787.0825309 0.863530025 1.347494324 1.359764429 1.15960872 1.272312159 1.635965222 1.339861 1.229109099 1.061724285 1 9.62037111 -7.255943254 24.91032771 0.935555843 1.338456028 0.621525342 0.127525219 180.0514332 816055.106 0.021574691 0.026020695 5.55E-08 7.255943254 0.402900185 LKS(ph)VEDEMDS(ph)PGEEPFYTGQGR ddPTM_HeLa_Curcumin_4h_R1 1 LKSVEDEMDSPGEEPFYTGQGR 22 1 A0A590UJA3;S4R3W2;A0A590UJU2;A0A590UK38;A0A590UK73;B1AKN7;B1AKN5;A0A590UK09;B1AKN8;Q12857-2;Q12857-3;Q12857;Q12857-4 A0A590UJA3 NFIA Nuclear factor 1;Nuclear factor 1 A-type 2 0 LKS(1)VEDEMDS(1)PGEEPFYTGQGR 101 6.82E-05 7794300 783 841.43 636.7 788.26 867.61 1002.1 1478.6 3304.8 775.62 923.35 TRUE FALSE FALSE 721.0247238 914.1594599 660.2966621 784.998389 857.2643174 794.253164 1520.085537 4312.418307 690.5364265 955.4363438 0.754654906 0.956797871 0.691094353 0.821612443 0.897249014 0.831298882 1.590985675 4.513558998 0.722744567 1 9.900015946 -4.245064772 2.47363334 0.866737133 5.420683649 0.991425691 0.102389281 0.038177631 0.276471575 0.016062552 0.372081437 5.69E-05 4.245064772 4.553946516 up TPS(ph)IQPSLLPHAAPFAK ddPTM_HeLa_Curcumin_4h_R1 1 TPSIQPSLLPHAAPFAK 17 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3;A0A0A0MSW3;H0YF36 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 0 T(0.158)PS(0.841)IQPSLLPHAAPFAK 111.93 0.00049835 44887000 2065.2 1463.8 1683.3 1879.2 2092.7 3219.5 2667.8 8367.4 2182.3 1885.3 TRUE FALSE FALSE 1901.737241 1590.324349 1745.684579 1871.424368 2067.745919 2551.739409 2742.651288 10918.58174 1942.90715 1950.814035 0.974842915 0.815210636 0.894849303 0.959304339 1.059940047 1.308038267 1.405900941 5.596936226 0.995946879 1 10.92986054 -4.244878079 3.381458954 0.994167596 6.288857054 0.991804745 0.12455889 0.022773532 0.417282127 0.019481739 0.316460469 5.69E-05 4.244878079 5.294689458 up PIPY(ph)WLY(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 PIPYWLYK 8 0 Q12874 Q12874 SF3A3 Splicing factor 3A subunit 3 2 0 PIPY(1)WLY(1)K 52.299 0.008856 0 853.29 1038.3 837.99 1025.6 879.55 724.62 819.41 745.9 1114.2 822.67 TRUE FALSE FALSE 785.7511961 1128.046025 869.0466466 1021.356339 869.0619407 574.3256438 842.4004393 973.3214763 991.9750476 851.2577213 0.923047364 1.32515218 1.020897226 1.199820352 1.020915193 0.674678924 0.989595064 1.143392244 1.165305198 1 9.733452169 -4.26066785 21.51634132 0.992491552 1.143392377 0 0.170593024 21.24484811 591535.3261 0.022372356 0.178941189 5.49E-05 4.26066785 0.150900825 PIS(ph)GS(ph)VS(ph)S(ph)ARPLGSSRGPGR ddPTM_HeLa_Curcumin_4h_R1 1 PISGSVSSARPLGSSRGPGR 20 2 Q68D10-2;Q68D10 Q68D10-2 SPTY2D1 Protein SPT2 homolog 4 0 PIS(1)GS(1)VS(1)S(1)ARPLGS(0.001)S(0.001)RGPGR 48.376 0.0083221 0 346.81 217.96 202.24 325.5 394.06 251.17 271.54 241.08 275.55 207.31 TRUE FALSE FALSE 319.3596225 236.7994912 209.7351923 324.1531672 389.3610919 199.0745107 279.1586816 314.5841822 245.3228544 214.5140071 1.488758832 1.103888247 0.977722598 1.5111049 1.815084699 0.928025696 1.301354095 1.46649716 1.143621611 1 7.744928044 -6.236708743 24.87129616 1.207872242 1.395036884 0.196338607 0.247368615 1439.540802 1447728.587 0.042626908 0.070669975 5.80E-07 6.236708743 0.187164643 PIS(ph)PSPSAILER ddPTM_HeLa_Curcumin_4h_R1 2 PISPSPSAILER 12 0 Q5T5P2;Q5T5P2-3;Q5T5P2-7;Q5T5P2-8;Q5T5P2-6;Q5T5P2-9;Q5T5P2-2;Q5T5P2-10;Q5T5P2-4;Q5T5P0;Q5T5P1 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 0 PIS(0.665)PS(0.33)PS(0.004)AILER;PIS(0.895)PS(0.104)PS(0.001)AILER ; 101.38 0.0085278 13146200 3214.1 2173.6 2451.3 2925.7 2670.7 1964.7 1201.97 966.76 2529.1 2308.1 TRUE FALSE FALSE 2959.700593 2361.476299 2542.147334 2913.594229 2638.853647 1557.199073 1235.694043 1261.520674 2251.664057 2388.306303 1.239246653 0.988766096 1.06441428 1.219941607 1.104905867 0.652009782 0.517393452 0.528207237 0.942786968 1 11.22177216 -5.189404852 3.452284685 1.111032689 0.533826457 0.863922292 0.093733399 0.063259942 1.471337349 0.014584134 0.040149665 6.47E-06 5.189404852 -0.577206233 PK(ac)K(ac)ATQFVYSYGRGPK ddPTM_HeLa_Curcumin_4h_R1 1 PKKATQFVYSYGRGPK 16 3 Q12986-3;Q12986-2;Q12986 Q12986-3 NFX1 Transcriptional repressor NF-X1 0 2 PK(1)K(1)ATQFVYSYGRGPK 52.527 0.014178 3655600 1260.4 1342.6 1284.7 1343 1310.4 2156.1 1359 1838.3 1608.3 1287.1 FALSE TRUE FALSE 1160.63801 1458.648361 1332.312112 1337.443022 1294.774336 1708.900556 1397.129882 2398.789208 1431.873514 1331.826629 0.871463286 1.095223905 1.000364524 1.00421706 0.972179342 1.283125385 1.049032848 1.80112723 1.075120051 1 10.37919058 -1.022723795 0.80624967 0.961195347 199.9999999 0.792338896 0.113807588 135.5697837 0.450925973 0.016738601 49319.12979 0.094902183 1.022723795 199.0388046 PKPSSS(ph)PVIFAGGQDR ddPTM_HeLa_Curcumin_4h_R1 2 PKPSSSPVIFAGGQDR 16 1 Q15366;Q15366-2;Q15366-3;Q15366-6;H3BSS4 Q15366 PCBP2 Poly(rC)-binding protein 2 1 0 PKPS(0.003)S(0.273)S(0.723)PVIFAGGQDR;PKPS(0.03)S(0.358)S(0.612)PVIFAGGQDR ; 81.788 0.0049821 99007000 5419 4697.2 5188.4 5167.4 4550.9 4850.5 4045 1673.82 3389.7 4084.3 TRUE FALSE FALSE 4990.080432 5103.205038 5380.686668 5146.018668 4496.63349 3844.451624 4158.491813 2184.160013 3017.858391 4226.229121 1.180740629 1.207507897 1.273164922 1.217638353 1.063982421 0.909664742 0.983972164 0.516810601 0.714078273 1 12.04515527 -4.002888561 1.073791434 1.117072477 3.23E-15 0.516395523 0.1593385 1.201355376 0.761494007 0.017630125 1.735886908 9.93E-05 4.002888561 -1.117072477 PLEGSSSEDSPPEGQAPPS(ph)HSPR ddPTM_HeLa_Curcumin_4h_R1 2 PLEGSSSEDSPPEGQAPPSHSPR 23 0 Q12789-3;Q12789 Q12789-3 GTF3C1 General transcription factor 3C polypeptide 1 1 0 PLEGSSSEDSPPEGQAPPS(0.5)HS(0.5)PR;PLEGSSSEDSPPEGQAPPS(0.732)HS(0.268)PR ; 117.38 2.18E-06 27651000 3445.7 3729.5 3787.8 3922.6 4075.4 3852.6 3075.35 2301 3084.04 3478.2 TRUE FALSE FALSE 3172.969209 4051.861362 3928.1792 3906.369321 4026.803517 3053.527332 3161.636044 3002.564307 2745.728528 3599.067191 0.881608773 1.125808757 1.091443697 1.085383827 1.118846441 0.848421874 0.878459855 0.83426181 0.762900047 1 11.81340732 -5.206790892 24.94465403 0.989154711 0.856188887 0.287298062 0.109146419 328.4876079 149939.644 0.014619865 0.037273458 6.21E-06 5.206790892 -0.132965824 PLENLEEEGLPKNPDLR ddPTM_HeLa_Curcumin_4h_R1 1 PLENLEEEGLPKNPDLR 17 1 Q15008;Q15008-4;C9J7B7 Q15008 PSMD6 26S proteasome non-ATPase regulatory subunit 6 0 0 95.873 0.0025531 3038200 1826.3 1318.5 1260.8 1811.9 1438.3 1004.9 869.32 992.36 1632.7 1643 FALSE FALSE TRUE 1681.746428 1432.465265 1307.526357 1804.402838 1421.149212 796.4724124 893.7107795 1294.925996 1453.596895 1700.094128 0.989207833 0.842579973 0.769090567 1.061354668 0.83592384 0.468487244 0.525683117 0.761679 0.855009656 1 10.73139891 -5.452300021 4.574296657 0.96716559 0.582637608 0.622323306 0.112753741 0.087960118 3.495971946 0.015774126 0.035785871 3.53E-06 5.452300021 -0.384527982 PLFPFRYICY(ph)FCWCYGNEILLLWK ddPTM_HeLa_Curcumin_4h_R1 1 PLFPFRYICYFCWCYGNEILLLWK 24 1 C9JDJ4 C9JDJ4 TMEM14B 1 0 PLFPFRY(0.095)ICY(0.893)FCWCY(0.012)GNEILLLWK 45.696 0.007606 0 100.82 0 0 0 0 0 81.33 133.38 0 0 TRUE FALSE FALSE 92.83999062 0 0 0 0 0 83.61190091 174.046948 0 0 0 PLGVTT(ph)WIQT(ph)VVTSPDT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 PLGVTTWIQTVVTSPDTPR 19 0 Q9P232 Q9P232 CNTN3 Contactin-3 3 0 PLGVT(0.217)T(0.795)WIQT(0.958)VVT(0.031)S(0.03)PDT(0.97)PR 80.596 0.0016416 10196000 2119.2 1746.9 1975.6 2214.3 2117 2615.3 1948 1247.3 2307 2003.5 TRUE FALSE FALSE 1951.463084 1897.894252 2048.817474 2205.137813 2091.756158 2072.857299 2002.655637 1627.596028 2053.927872 2073.121476 0.941316323 0.915476625 0.988276615 1.063679982 1.008988707 0.999872571 0.966009788 0.785094384 0.990741689 1 11.01758894 -4.26333557 4.613538102 0.97956689 0.773283402 0.713023224 0.038140286 0.090617373 5.09571075 0.006034106 0.060121062 5.45E-05 4.26333557 -0.206283488 PLISVYSEK ddPTM_HeLa_Curcumin_4h_R1 2 PLISVYSEK 9 0 P36578;H3BTP7;H3BU31 P36578 RPL4 60S ribosomal protein L4 0 0 ; ; 149.94 3.80E-06 2506100 2830.6 1873.95 2138.6 2799.4 2383.2 2029.53 2246.2 1922.67 1729.01 2205.2 FALSE FALSE TRUE 2606.555023 2035.925888 2217.858397 2787.816825 2354.781897 1608.5826 2309.222327 2508.883232 1539.341929 2281.830536 1.142308766 0.892233606 0.971964553 1.221745779 1.031970543 0.704952701 1.012004305 1.099504627 0.674608348 1 11.15597594 -5.500111579 24.90008012 1.05874609 0.933192709 0 0.17486749 1028.47524 1124825.179 0.018338985 0.040726543 3.16E-06 5.500111579 -0.12555338 PLLSQEDS(ph)EEEENELEAINRK ddPTM_HeLa_Curcumin_4h_R1 2 PLLSQEDSEEEENELEAINRK 21 1 Q9H1H9-3;Q9H1H9-4;Q9H1H9-2 Q9H1H9-3 KIF13A Kinesin-like protein KIF13A 1 0 PLLS(0.006)QEDS(0.994)EEEENELEAINRK;PLLS(0.136)QEDS(0.864)EEEENELEAINRK ; 95.209 0.00014835 49110000 3511.8 2894.93 2904.89 3681.77 2761.59 3254.3 2593.66 1971.7 2762.27 3106.41 TRUE FALSE FALSE 3233.837324 3145.15485 3012.547779 3666.535811 2728.659843 2579.321496 2666.431119 2572.862253 2459.255892 3214.357516 1.006060249 0.978470762 0.937216151 1.140674549 0.848897433 0.802437652 0.829537818 0.800428154 0.765084742 1 11.65031469 -5.598858059 8.68579749 1.003955804 0.814813019 0.376877845 0.090260203 0.086364064 8.913907238 0.006469359 0.012960376 2.52E-06 5.598858059 -0.189142785 EAPAEGEAAEPGS(ph)PTAAEGEAASAASSTSSPK ddPTM_HeLa_Curcumin_4h_R1 4 EAPAEGEAAEPGSPTAAEGEAASAASSTSSPK 32 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 EAPAEGEAAEPGS(0.5)PT(0.5)AAEGEAASAASSTSSPK;EAPAEGEAAEPGS(0.5)PT(0.5)AAEGEAASAASSTSSPK;EAPAEGEAAEPGS(0.912)PT(0.088)AAEGEAASAASSTSSPK;EAPAEGEAAEPGS(0.816)PT(0.184)AAEGEAASAASSTSSPK ;;; 148.3 7.92E-14 233080000 9180 7354.2 8205.2 8716.4 8817.7 12381.1 15574.5 52888 8921.3 8012.1 TRUE FALSE FALSE 8453.393313 7989.864278 8509.29193 8680.333846 8712.554687 9813.120296 16011.47855 69013.30773 7942.65571 8290.519879 1.019645744 0.963735012 1.026388219 1.047019243 1.050905711 1.183655602 1.9312997 8.324364303 0.958040729 1 13.01724686 -4.244823788 3.051129891 1.026916722 9.643205706 0.998922535 0.071406302 0.012257297 0.163147849 0.014223957 0.259309938 5.69E-05 4.244823788 8.616288984 up PLPS(ph)PGAAGAQALEK ddPTM_HeLa_Curcumin_4h_R1 2 PLPSPGAAGAQALEK 15 0 H9KVB4;O15417-2;O15417;O15417-3 H9KVB4 TNRC18 Trinucleotide repeat-containing gene 18 protein 1 0 PLPS(1)PGAAGAQALEK;PLPS(1)PGAAGAQALEK ; 102.72 0.0030301 7972800 4056.1 4002.7 3918 3667.9 3931.8 4028.9 3849.4 1724.55 3290.4 3303.4 TRUE FALSE FALSE 3735.055405 4348.675552 4063.204527 3652.723202 3884.915853 3193.260725 3957.403804 2250.357356 2929.451352 3418.192904 1.092698835 1.272214786 1.188699597 1.068612365 1.136540845 0.934195587 1.157747358 0.658347091 0.857017563 1 11.7390181 -4.254479988 24.85434692 1.075714565 0.658346881 0.539314701 0.116505273 397.3494104 1419030.047 0.01392045 0.184595411 5.57E-05 4.254479988 -0.417367683 DHFLGPQESFPEENASS(ph)PFTQAR ddPTM_HeLa_Curcumin_4h_R1 2 DHFLGPQESFPEENASSPFTQAR 23 0 A0A0U1RRL2;B1AM27;O14795;O14795-2;A0A1B0GUS7 A0A0U1RRL2 UNC13B Protein unc-13 homolog B 1 0 DHFLGPQESFPEENAS(0.207)S(0.675)PFT(0.118)QAR;DHFLGPQESFPEENAS(0.215)S(0.679)PFT(0.106)QAR ; 204 4.05E-18 14431300 5910.1 5092.6 5161.5 5668.3 5169 5919.4 3668.3 1642.16 6261.7 5009.5 TRUE FALSE FALSE 5442.309349 5532.781652 5352.789731 5644.846077 5107.363051 4691.649715 3771.222625 2142.847024 5574.807176 5183.579752 1.049913305 1.067366939 1.03264346 1.088986057 0.985296512 0.905098395 0.727532479 0.413391349 1.075474371 1 12.33973304 -4.291421412 1.13600382 1.032828687 0.131696494 0.977263911 0.030399914 0.166729683 0.178603631 0.00490527 0.176209839 5.11E-05 4.291421412 -0.901132193 down PMEEDGEEKS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 PMEEDGEEKSPSK 13 1 Q12906;Q12906-7;Q12906-5;Q12906-4;Q12906-2;Q12906-6;Q12906-3 Q12906 ILF3 Interleukin enhancer-binding factor 3 1 0 PMEEDGEEKS(0.855)PS(0.145)K 68.329 0.016663 96750000 7547.5 5684.7 6398.7 6804.7 6945 7103.3 6828.7 5170.7 6236.6 6033.3 TRUE FALSE FALSE 6950.107411 6176.060137 6635.841451 6776.543954 6862.185411 5629.995509 7020.294943 6747.222627 5552.460583 6242.956726 1.113271758 0.98928447 1.062932476 1.085470275 1.099188367 0.901815559 1.124514433 1.08077357 0.889395975 1 12.60801375 PMFIVNTNVPR ddPTM_HeLa_Curcumin_4h_R1 1 PMFIVNTNVPR 11 0 P14174 P14174 MIF Macrophage migration inhibitory factor 0 0 160.36 1.14E-07 1314800 517.62 263.19 540.31 314.11 321.42 494.88 539.2 617.41 253.24 312.44 FALSE FALSE TRUE 476.6498308 285.9389708 560.3343639 312.810296 317.5872764 392.2363096 554.3285008 805.6554668 225.4602056 323.2972667 1.474339191 0.884445989 1.733186208 0.967562452 0.982338266 1.21323732 1.714609302 2.491995911 0.697377395 1 8.3367175 -4.3861596 2.168866588 1.203559305 2.655885625 0.674205513 0.293998647 0.207618475 1.328526867 0.037040209 0.522334028 4.11E-05 4.3861596 1.45232632 PMKNKPGPY(ph)S(ph)S(ph)VPPPSAPPPK ddPTM_HeLa_Curcumin_4h_R1 1 PMKNKPGPYSSVPPPSAPPPK 21 2 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2;S4R349 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 3 0 PMKNKPGPY(0.905)S(0.912)S(0.912)VPPPS(0.271)APPPK 47.752 0.009593 3561000 1889.5 1503.6 1316.9 1813.2 1583.4 2072.9 1647.4 1297.2 2279.1 1808.4 TRUE FALSE FALSE 1739.944081 1633.564484 1365.705472 1805.697459 1564.518989 1642.957174 1693.62161 1692.710308 2029.088432 1871.241765 0.929833928 0.872984194 0.729839136 0.964972828 0.836085971 0.878003689 0.905078992 0.904591988 1.084353967 1 10.86978025 -7.830574572 1.239887771 0.981584049 0.870539751 0.457714234 0.066797667 0.282694474 0.909206689 0.01351655 0.012306836 1.48E-08 7.830574572 -0.111044298 PNNSGEAPSS(ph)PTPK ddPTM_HeLa_Curcumin_4h_R1 2 PNNSGEAPSSPTPK 14 0 K7ENR9;K7ERZ5;P49916-4;P49916-3;P49916-2;P49916 K7ENR9 LIG3 DNA ligase 3 1 0 PNNSGEAPS(0.292)S(0.707)PT(0.002)PK;PNNS(0.001)GEAPS(0.298)S(0.698)PT(0.004)PK ; 175.66 0.0001885 20871800 9157.1 7899.6 9161.9 9078 10530.5 7486.7 8158 4479.6 6502.1 7605.2 TRUE FALSE FALSE 8432.305872 8582.406224 9501.448074 9040.437641 10404.93067 5933.874028 8386.891524 5845.409418 5788.835897 7869.480134 1.071520066 1.090593798 1.207379384 1.148797314 1.322187805 0.754036344 1.06574912 0.742794863 0.735605885 1 12.94205262 -3.623854214 1.037832257 1.068709041 2.78E-09 0.209857342 0.173558933 5.437139282 1.800592055 0.020681969 8.874366197 0.000237764 3.623854214 -1.068709038 PNNSGEAPSSPT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 PNNSGEAPSSPTPK 14 0 K7ENR9;K7ERZ5;P49916-4;P49916-3;P49916-2;P49916 K7ENR9 LIG3 DNA ligase 3 1 0 PNNSGEAPS(0.018)S(0.062)PT(0.92)PK 115.83 0.0061959 5435900 2356.7 1876.2 2322.1 2609.5 2366.6 1973.8 1837.7 1255.9 1667.6 2038.6 TRUE FALSE FALSE 2170.164708 2038.370368 2408.159069 2598.70258 2338.379841 1564.411631 1889.260916 1638.818129 1484.668452 2109.441198 1.028786538 0.966308219 1.141609954 1.231938858 1.108530469 0.741623721 0.895621512 0.776896806 0.703820734 1 11.04264516 -5.262354579 24.99988765 1.042368794 0.813804758 0.351114114 0.136311729 45.97570614 1255908.849 0.013285042 0.031427086 5.47E-06 5.262354579 -0.228564036 PPET(ph)ADEEQVES(ph)FT(ph)S(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 PPETADEEQVESFTSK 16 0 A0A6I8PIP2;A0A6I8PU78;A0A6I8PIF8;A0A5F9ZHQ6;O75071 A0A6I8PIP2 EFCAB14 EF-hand calcium-binding domain-containing protein 14 4 0 PPET(1)ADEEQVES(1)FT(1)S(1)K 73.953 0.0055273 0 1152.6 1096.7 1118.7 1007.5 986.44 1050.5 1030.6 1070.7 1310.7 1182.5 TRUE FALSE FALSE 1061.370494 1191.493861 1160.160006 1003.331232 974.6773473 832.6144584 1059.515862 1397.151501 1166.919489 1223.591787 0.867422048 0.973767456 0.94815936 0.819988531 0.796570684 0.680467512 0.865906321 1.141844458 0.953683656 1 10.25690661 -6.269185659 23.83885358 0.939844202 0.847626502 0.122486354 0.113351749 515.552808 1586591.293 0.018194003 0.028133912 5.38E-07 6.269185659 -0.0922177 PPS(ph)AQDGLGST(ph)RGPPSS(ph)LPQR ddPTM_HeLa_Curcumin_4h_R1 1 PPSAQDGLGSTRGPPSSLPQR 21 1 H3BS19;Q96JG9 H3BS19 ZNF469 Zinc finger protein 469 3 0 PPS(0.945)AQDGLGS(0.265)T(0.769)RGPPS(0.041)S(0.981)LPQR 57.267 0.0072638 0 1043.4 670.36 670.59 849.72 898.28 1122 747.53 759.33 951.52 743.94 TRUE FALSE FALSE 960.813789 728.3029313 695.4426553 846.2040838 887.5685977 889.2845525 768.5036799 990.8462215 847.1406366 769.7918596 1.248147505 0.946103706 0.903416484 1.099263487 1.15299816 1.155227275 0.998326587 1.28716121 1.100480118 1 9.588324605 -4.242369994 23.59433019 1.091494524 1.287161593 0.264892346 0.1029996 2688.645386 3326516.573 0.017154329 0.755703398 5.72E-05 4.242369994 0.195667069 PPT(ph)EQANVLLS(ph)FQMT(ph)S(ph)DELPK ddPTM_HeLa_Curcumin_4h_R1 1 PPTEQANVLLSFQMTSDELPK 21 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3;H7C103 Q9H8V3-2 ECT2 Protein ECT2 4 0 PPT(1)EQANVLLS(1)FQMT(1)S(1)DELPK 43.955 0.015059 21400000 417.51 319.84 315.27 477.81 431.69 414.28 260.46 296.61 551.01 480.65 TRUE FALSE FALSE 384.4636429 347.4855444 326.9541835 475.8329488 426.5423787 328.3536581 267.7678066 387.0450236 490.5655816 497.3525517 0.773020349 0.698670477 0.657389175 0.956731693 0.857625797 0.660203023 0.538386313 0.778210592 0.986353804 1 8.958125068 -13.52287875 0.162859663 2.062947988 0.660673234 0.467885747 0.108573174 42.07151776 0.454373995 14.13145583 0.21161569 3.00E-14 13.52287875 -1.402274755 PPY(ph)T(ph)LAAADYCIPS(ph)FLGST(ph)VQMGK ddPTM_HeLa_Curcumin_4h_R1 1 PPYTLAAADYCIPSFLGSTVQMGK 24 0 Q8N1M1-1 Q8N1M1-1 4 0 PPY(0.891)T(0.984)LAAADY(0.127)CIPS(0.935)FLGS(0.5)T(0.563)VQMGK 43.799 0.0076135 0 218.71 282.02 428.68 250.24 240.84 260.57 120.83 308.07 232.21 209.66 TRUE FALSE FALSE 201.3988727 306.3965521 444.5672579 249.2045732 237.9681403 206.5248448 124.2201646 401.9991248 206.737144 216.9456694 0.928337834 1.412319283 2.049210105 1.148695772 1.096902008 0.95196574 0.572586514 1.852994466 0.952944323 1 7.761189978 -7.273994285 24.0978894 0.96615952 1.272053146 0.127626157 0.400186852 800.4902716 1536458.117 0.068987422 0.079193779 5.32E-08 7.273994285 0.305893626 PQYQTWEEFSR ddPTM_HeLa_Curcumin_4h_R1 1 PQYQTWEEFSR 11 0 Q6P2S0;Q659G3;E9PE20;P49458-2;P49458 Q6P2S0 SRP9;DKFZp564M2223 Signal recognition particle 9 kDa protein 0 0 169.99 0.0020545 16669000 1324.2 908.45 898.56 1189.9 949.47 1275 1164.4 884.43 1086.8 1093.1 FALSE FALSE TRUE 1219.388173 986.97237 931.8614241 1184.976509 938.1481904 1010.550628 1197.06993 1154.088636 967.580759 1131.085144 1.078069303 0.872588925 0.823864967 1.047645719 0.829423139 0.893434622 1.058337595 1.020337542 0.855444671 1 10.14349182 -7.268453343 24.97160356 1.03686606 0.934215522 0 0.100139827 584.6308459 2081441.526 0.014493537 0.016774225 5.39E-08 7.268453343 -0.102650539 PRAS(ph)PPPQGPLPGPPGALHR ddPTM_HeLa_Curcumin_4h_R1 1 PRASPPPQGPLPGPPGALHR 20 1 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 0 PRAS(1)PPPQGPLPGPPGALHR 97.059 0.00031856 23821000 972.5 728.46 1071.6 902.68 745.7 977.66 775.76 460.1 881.85 953.73 TRUE FALSE FALSE 895.5255988 791.4248364 1111.314439 898.9449493 736.8080145 774.8822955 797.5257377 600.382372 785.1132613 986.8720465 0.907438408 0.801952836 1.126097798 0.910903245 0.746609469 0.785190236 0.808134895 0.608369012 0.795557301 1 9.946719233 -3.084909355 0.345805859 0.969859845 9.55E-15 0.394142031 0.106163778 7.567431873 0.340786326 0.029152895 3.636363893 0.000822414 3.084909355 -0.969859845 PRHY(ph)RAPS(ph)HDK ddPTM_HeLa_Curcumin_4h_R1 1 PRHYRAPSHDK 11 2 Q96R30 Q96R30 OR2V2 Olfactory receptor 2V2 2 0 PRHY(1)RAPS(1)HDK 100.04 0.013471 4386600 1408.3 880.66 801.78 816.33 1085.8 2746.8 871.48 743.74 973.53 876.77 TRUE FALSE FALSE 1296.831569 956.7803263 831.4946721 812.9522428 1072.852544 2177.082717 895.9313833 970.5029022 866.7361947 907.2376922 1.429428671 1.054608218 0.916512485 0.896074149 1.182548469 2.399682835 0.987537655 1.069733886 0.955357347 1 9.82533677 -9.60178502 1.388736304 0.999474282 1.267711381 0.056294165 0.417477138 1.216146674 4.195726504 0.30392279 0.069622493 2.50E-10 9.60178502 0.2682371 PRPVS(ph)PSSLLDTAISEEAR ddPTM_HeLa_Curcumin_4h_R1 1 PRPVSPSSLLDTAISEEAR 19 1 A0A0B4J2F2;P57059 A0A0B4J2F2 LOC102724428;SIK1 Serine/threonine-protein kinase SIK1 1 0 PRPVS(0.994)PS(0.004)S(0.001)LLDTAISEEAR 101.33 0.00047231 0 384.95 254.69 271.62 336.45 307.89 371.1 146.28 230.8 425.61 279.99 TRUE FALSE FALSE 354.4808013 276.7042687 281.6864761 335.057859 304.2186128 294.1296768 150.3842231 301.1698575 378.9216478 289.7196317 1.223530485 0.955076006 0.972272657 1.156490008 1.05004487 1.015221769 0.519068115 1.039521747 1.307890824 1 8.178513636 -4.977832813 24.19875594 1.084709356 0.776257019 0.384167079 0.157325237 109.2271207 119235.2893 0.019543418 0.058622922 1.05E-05 4.977832813 -0.308452337 PRS(ph)PQPPSR ddPTM_HeLa_Curcumin_4h_R1 1 PRSPQPPSR 9 1 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 0 PRS(1)PQPPSR 74.698 0.017209 7330600 413.76 567.52 306.45 386.7 313.75 331.57 374.43 138.14 328.95 358.01 TRUE FALSE FALSE 381.0104594 616.5739 317.8073066 385.0999379 310.0087362 262.7986444 384.9354981 180.2582501 292.865008 370.4508209 1.028504832 1.664387998 0.857893379 1.039544026 0.836841812 0.709402246 1.039100135 0.48659158 0.790563798 1 8.53313822 -5.737844752 2.03545033 1.060920474 0.768051567 0.250429599 0.253021948 0.360816263 3.042790521 0.035290615 0.078863627 1.83E-06 5.737844752 -0.292868907 PRT(ph)AS(ph)TAETPRR ddPTM_HeLa_Curcumin_4h_R1 1 PRTASTAETPRR 12 2 E9PJY3;Q9C0D2-4;Q9C0D2-3 E9PJY3 CEP295 2 0 PRT(1)AS(1)TAETPRR 67.214 0.014166 23438000 924.96 675.65 739.31 952.32 1097.9 1271.4 938.16 856.19 986.55 667.03 TRUE FALSE FALSE 851.74844 734.0501754 766.709479 948.3795522 1084.80826 1007.697308 964.4822447 1117.23839 878.3279332 690.2092429 1.234043805 1.063518321 1.110836296 1.374046439 1.571709262 1.45998814 1.397376599 1.618695202 1.272553131 1 9.430889983 -6.13661185 3.172114672 1.108429953 1.498973426 0.777370382 0.094568519 0.091473989 1.744364706 0.015607804 0.027106255 7.30E-07 6.13661185 0.390543473 PRYRRLILK ddPTM_HeLa_Curcumin_4h_R1 1 PRYRRLILK 9 3 Q8NC38 Q8NC38 ZNF436-AS1 Putative uncharacterized protein ZNF436-AS1 0 0 81.594 0.0070729 0 690.01 528.92 572.09 804.9 533.98 545.07 527.33 510.61 735.63 815.27 FALSE FALSE TRUE 635.3949804 574.637488 593.2921587 801.5695371 527.6126373 432.0163378 542.1254606 666.2926384 654.9332295 843.6005718 0.753194108 0.681172473 0.703285629 0.950176617 0.625429445 0.512110058 0.642632875 0.789820041 0.776354653 1 9.720416263 -9.910239286 0.252829161 1.251288562 0.64607872 0.155536366 0.128318839 4.61765886 0.301896538 0.868207457 0.089738782 1.23E-10 9.910239286 -0.605209842 PS(ph)EVMMMMFLAPVK ddPTM_HeLa_Curcumin_4h_R1 1 PSEVMMMMFLAPVK 14 0 F5H5G4 F5H5G4 WBP11 1 0 PS(1)EVMMMMFLAPVK 45.357 0.0095452 0 907.75 916.57 828.19 802.84 1053.4 812.33 905.26 699.97 1009.6 919.38 TRUE FALSE FALSE 835.9006296 995.7942266 858.88345 799.5180608 1040.838893 643.8436012 930.6591592 913.3876307 898.8494059 951.3283866 0.878666758 1.04674079 0.90282542 0.840422794 1.094090019 0.676783759 0.978273299 0.960118129 0.944836103 1 9.893799617 -9.531522374 1.200085244 1.001500726 0.917252712 0.021500071 0.11031849 1.077327313 2.696033349 0.077306199 0.017127944 2.94E-10 9.531522374 -0.084248014 PS(ph)S(ph)AS(ph)T(ph)VTTTKS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 PSSASTVTTTKSK 13 1 Q96IQ7 Q96IQ7 VSIG2 V-set and immunoglobulin domain-containing protein 2 5 0 PS(0.995)S(0.996)AS(0.884)T(0.385)VT(0.303)T(0.405)T(0.133)KS(0.898)K 45.137 0.018159 5424500 121.39 0 55.947 136.24 136.27 159.35 122.44 0 0 123.13 TRUE FALSE FALSE 111.7818534 0 58.02044504 135.676275 134.6450693 126.2990138 125.8753369 0 0 127.4087583 0.877348268 0 0.455388199 1.064889704 1.056796024 0.991289888 0.987964552 0 0 1 6.993320645 -7.502490293 22.27063279 0.945889998 0.682238103 0 0.485354702 94.81422088 103571.6569 0.069045395 0.07411315 3.14E-08 7.502490293 -0.263651895 PS(ph)S(ph)QPIMS(ph)QS(ph)LPK ddPTM_HeLa_Curcumin_4h_R1 3 PSSQPIMSQSLPK 13 0 B7ZM87;O75044;A0A075B7E9 B7ZM87 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 4 0 PS(1)S(1)QPIMS(1)QS(1)LPK;PS(1)S(1)QPIMS(1)QS(1)LPK;PS(1)S(1)QPIMS(1)QS(1)LPK ;; 53.924 0.0091411 0 4120.82 3440.1 3568.44 3758.68 4049.92 4842.91 3710.47 3366.96 4174.36 3672.24 TRUE FALSE FALSE 3794.652749 3737.446915 3700.689526 3743.127578 4001.627349 3838.435875 3814.575802 4393.530604 3716.443152 3799.850067 0.998632231 0.98357747 0.973904091 0.98507244 1.05310138 1.010154561 1.003875346 1.156237885 0.978049946 1 11.89172678 -4.260741903 5.892077628 1.000016647 1.160790316 0.830160042 0.021402989 0.038734838 6.116395341 0.002830917 0.024802738 5.49E-05 4.260741903 0.160773669 PS(ph)S(ph)T(ph)S(ph)AS(ph)QGAK ddPTM_HeLa_Curcumin_4h_R1 1 PSSTSASQGAK 11 0 A0A075B749;Q5VU43-3;Q5VU43;Q5VU43-4 A0A075B749 PDE4DIP Myomegalin 5 0 PS(1)S(1)T(1)S(1)AS(1)QGAK 60.49 0.0083557 0 496.11 667.53 547.1 506.13 518.27 592.37 525.22 1049.4 614.64 779.53 TRUE FALSE FALSE 456.84237 725.2283187 567.3760073 504.0357682 512.0899687 469.5057846 539.9562596 1369.357229 547.2155298 806.6186095 0.566367258 0.899096934 0.703400592 0.624874956 0.634860097 0.582066641 0.669407144 1.697651422 0.678406775 1 9.65574288 -4.258482736 24.93203003 0.749667143 1.69765178 0.821009505 0.137513151 113.3603502 955864.3618 0.025526844 0.239307488 5.51E-05 4.258482736 0.947984637 PSADLTNSSAPSPS(ph)HK ddPTM_HeLa_Curcumin_4h_R1 1 PSADLTNSSAPSPSHK 16 0 E7ETY4;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E9PC69;Q7KZI7-14;Q7KZI7-6;Q7KZI7-10;Q7KZI7-12;Q7KZI7-8;Q7KZI7-11;Q7KZI7-9;Q7KZI7-3;Q7KZI7-4;Q7KZI7-5;Q7KZI7-2;Q7KZI7-7;Q7KZI7 E7ETY4 MARK2 Serine/threonine-protein kinase MARK2 1 0 PSADLT(0.001)NS(0.014)S(0.008)APS(0.38)PS(0.597)HK 161.91 5.63E-11 0 1976.7 1429.2 1811.1 1700.3 1661.1 1925.4 1746.2 583.81 1396.8 1241.6 TRUE FALSE FALSE 1820.242109 1552.73368 1878.220959 1693.264609 1641.292467 1526.050336 1795.193672 761.8109815 1243.574535 1284.745508 1.416811422 1.208592418 1.461940087 1.317976673 1.277523414 1.187823057 1.397314613 0.592966449 0.967953986 1 10.32726689 -4.252877795 24.79205445 1.241832868 0.592966081 0.609176052 0.157424825 576.3550734 1668928.35 0.024302008 0.374164751 5.59E-05 4.252877795 -0.648866787 PSDSVSSTPAATST(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 PSDSVSSTPAATSTPSK 17 0 H0Y5D5;A0A494C0L7;Q9BTG3;Q5SYW2;F5H2X7;Q9ULV3-5;Q9ULV3-3;Q9ULV3-4;Q9ULV3-2;Q9ULV3 H0Y5D5 CIZ1 Cip1-interacting zinc finger protein 1 0 PSDSVSSTPAATS(0.022)T(0.972)PS(0.006)K;PSDSVSSTPAATS(0.093)T(0.907)PSK ; 266.07 1.13E-51 19645700 7980.5 8055.6 8304.4 8290.4 8923.1 9717.6 9818 3270.9 6609 7359.9 TRUE FALSE FALSE 7348.835004 8751.890169 8612.168369 8256.096521 8816.69786 7702.06022 10093.46666 4268.182353 5884.009235 7615.655977 0.964964151 1.149197153 1.1308505 1.084095257 1.157706951 1.011345607 1.325357485 0.560448419 0.772620146 1 12.89475259 -7.286513748 23.87700036 0.983455287 1.075629237 0.068288653 0.198051767 1001.108568 953299.988 0.02836009 0.032439783 5.17E-08 7.286513748 0.09217395 PSELVSGSNSIISFS(ph)S(ph)VIS(ph)MAK ddPTM_HeLa_Curcumin_4h_R1 1 PSELVSGSNSIISFSSVISMAK 22 0 Q96KN7 Q96KN7 RPGRIP1 X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 3 0 PS(0.003)ELVS(0.003)GS(0.004)NS(0.029)IIS(0.143)FS(0.871)S(0.974)VIS(0.974)MAK 46.702 0.012865 3949400 1220.3 629.3 1029.3 1317.3 1071.8 1416.4 1241.5 1545 1251.7 1141.5 TRUE FALSE FALSE 1123.711967 683.6938879 1067.446763 1311.849362 1059.019485 1122.622674 1276.333149 2016.063388 1114.391642 1181.16704 0.951357369 0.578829128 0.903722105 1.110638307 0.8965874 0.950435151 1.08056956 1.706840201 0.943466592 1 10.20599729 -4.240211808 2.563791356 0.945382678 1.89248716 0.765854619 0.130040481 0.206766358 1.638171662 0.018779404 0.431273009 5.75E-05 4.240211808 0.947104482 PSGGFVISGVLS(ph)PDTISSKR ddPTM_HeLa_Curcumin_4h_R1 1 PSGGFVISGVLSPDTISSKR 20 1 Q03188;H0Y8J2;H0Y9W1 Q03188 CENPC Centromere protein C 1 0 PSGGFVIS(0.005)GVLS(0.994)PDTISSKR 75.539 0.0019565 8685200 679.42 461.06 462.06 595.03 468.51 501.59 457.33 269.08 568.46 619.62 TRUE FALSE FALSE 625.6431901 500.911972 479.1843501 592.5679235 462.9233242 397.5545799 470.161449 351.1212533 506.1013602 641.1517489 0.975811407 0.781268979 0.747380555 0.92422414 0.722018344 0.620063161 0.733307598 0.547641419 0.789362832 1 9.324522047 -5.780762713 0.351460903 1.020488658 0.508729563 0.457731718 0.102471765 0.830943133 0.155678829 0.033795205 0.162586868 1.66E-06 5.780762713 -0.511759095 PSLFVLS(ph)PIKEPAK ddPTM_HeLa_Curcumin_4h_R1 2 PSLFVLSPIKEPAK 14 1 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 0 PS(0.003)LFVLS(0.997)PIKEPAK;PS(0.008)LFVLS(0.992)PIKEPAK ; 107.03 0.0014967 115462000 15101.4 12357.9 12864.6 15850.3 13037.1 3163.6 6409.9 6552.7 11751.2 14162.9 TRUE FALSE FALSE 13906.10826 13426.06181 13341.37339 15784.71566 12881.6411 2507.433699 6589.744543 8550.588065 10462.12276 14655.05972 0.948894683 0.916138321 0.910359538 1.077082998 0.878989328 0.171096792 0.449656615 0.583456378 0.713891513 1 13.83911123 -5.38408775 5.74155532 0.971201858 0.409267394 0.759137068 0.132704055 0.055915661 2.396053995 0.014253201 0.032264725 4.13E-06 5.38408775 -0.561934465 QEKPAEKPAETPVATS(ph)PTATDSTSGDSSR ddPTM_HeLa_Curcumin_4h_R1 5 QEKPAEKPAETPVATSPTATDSTSGDSSR 29 2 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 0 QEKPAEKPAET(0.022)PVAT(0.287)S(0.668)PT(0.019)AT(0.002)DSTSGDSSR;QEKPAEKPAET(0.008)PVAT(0.117)S(0.848)PT(0.025)AT(0.003)DSTSGDSSR;QEKPAEKPAETPVAT(0.237)S(0.718)PT(0.029)AT(0.014)DS(0.001)TSGDSSR;QEKPAEKPAETPVAT(0.261)S(0.727)PT(0.012)ATDSTSGDSSR;QEKPAEKPAET(0.01)PVAT(0.446)S(0.462)PT(0.051)AT(0.024)DS(0.002)T(0.001)S(0.001)GDS(0.001)S(0.001)R ;;;; 112.29 3.03E-11 1300832000 10999.48 9061.26 9554.07 9634.06 9422.57 13522.66 12269.71 25535.5 10941.49 9461.23 TRUE FALSE FALSE 10128.85955 9844.474938 9908.152239 9594.196812 9310.212007 10717.90788 12613.96504 33321.1564 9741.235921 9790.007038 1.034612081 1.005563622 1.012067938 0.97999897 0.95099135 1.094780406 1.288453113 3.403588605 0.995018276 1 13.25709418 -4.244538385 3.127841681 1.014304886 3.818242961 0.997176054 0.037983838 0.01598814 0.229405092 0.006299328 0.1118888 5.69E-05 4.244538385 2.803938075 up KLEKEEEEGISQES(ph)SEEEQ ddPTM_HeLa_Curcumin_4h_R1 2 KLEKEEEEGISQESSEEEQ 19 2 P17096;P17096-2 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 0 KLEKEEEEGIS(0.021)QES(0.489)S(0.489)EEEQ;KLEKEEEEGIS(0.077)QES(0.462)S(0.462)EEEQ ; 61.87 0.014221 60179000 7418 5578.9 6019.9 6377.2 5448.6 9343.1 7647.3 16346.4 8182.6 6036.1 TRUE FALSE FALSE 6830.857473 6061.115257 6243.00279 6350.812836 5383.629004 7405.235742 7861.862656 21330.34211 7284.989252 6245.854026 1.093662683 0.970422176 0.999543499 1.016804557 0.861952422 1.185624209 1.258733013 3.415120178 1.166372 1 12.60868314 -4.243952694 3.299432634 1.03175673 3.792915182 0.98381246 0.090948102 0.027730666 0.469066526 0.011770136 0.19796189 5.70E-05 4.243952694 2.761158452 up PSPT(ph)CS(ph)SIGLHK ddPTM_HeLa_Curcumin_4h_R1 1 PSPTCSSIGLHK 12 0 Q13395 Q13395 TARBP1 Probable methyltransferase TARBP1 2 0 PS(0.018)PT(0.984)CS(0.985)S(0.013)IGLHK 86.944 0.018356 8444400 1097.6 1320.7 1289.3 1172.6 1126 1408.6 1334.4 957.5 1169.2 1404.6 TRUE FALSE FALSE 1010.723802 1434.855423 1337.082592 1167.748092 1112.573185 1116.440482 1371.839673 1249.437342 1040.941685 1453.409745 0.695415594 0.987233936 0.919962589 0.80345415 0.765491761 0.768152605 0.943876754 0.859659395 0.716206623 1 10.50522577 -6.233664741 24.53566627 0.86877965 0.827745843 0.027031361 0.10474989 2379.638595 2102133.107 0.019391148 0.03215181 5.84E-07 6.233664741 -0.041033807 PSS(ph)PGGLPEEDSVLFNK ddPTM_HeLa_Curcumin_4h_R1 2 PSSPGGLPEEDSVLFNK 17 0 A0A0U1RQY6;A0A0C4DG54;Q5R372-2;Q5R372-4;Q5R372;Q5R372-3 A0A0U1RQY6 RABGAP1L Rab GTPase-activating protein 1-like 1 0 PS(0.137)S(0.853)PGGLPEEDS(0.01)VLFNK;PS(0.142)S(0.858)PGGLPEEDSVLFNK ; 176.25 3.09E-18 5440000 2257.85 2114.1 2192.88 2450.9 2306.8 2232.99 1942.99 2165.86 2076.21 2027.5 TRUE FALSE FALSE 2079.13879 2296.833384 2274.150062 2440.758825 2279.292917 1769.842703 1997.50507 2826.220744 1848.454957 2097.955474 0.991030942 1.094796058 1.08398395 1.163398773 1.086435315 0.843603558 0.952119859 1.347130947 0.881074446 1 11.03476834 -4.254934913 24.63653629 1.013063118 1.347131132 0.530222279 0.09497475 357.3005311 1353278.901 0.01239263 0.157531256 5.56E-05 4.254934913 0.334068014 PSS(ph)SPVIFAGGQDR ddPTM_HeLa_Curcumin_4h_R1 1 PSSSPVIFAGGQDR 14 0 Q15366;Q15366-2;Q15366-3;Q15366-6;H3BSS4 Q15366 PCBP2 Poly(rC)-binding protein 2 1 0 PS(0.001)S(0.907)S(0.092)PVIFAGGQDR 183.28 8.41E-05 54517000 2932.1 2083.1 2517.2 2922.7 2580.2 2308.3 2043.4 857.94 1821.6 2001.8 TRUE FALSE FALSE 2700.021191 2263.153882 2610.489646 2910.606642 2549.4328 1829.53256 2100.732304 1119.521957 1621.775037 2071.362401 1.303500145 1.092591949 1.26027664 1.405165335 1.230799979 0.88325083 1.014179027 0.540476141 0.782950891 1 11.01636427 -4.026072047 1.084650953 1.170869666 3.17E-13 0.481626431 0.180946805 1.449965167 0.970357993 0.024137232 2.189856589 9.42E-05 4.026072047 -1.170869666 PSSIPAPAEAEAWS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 PSSIPAPAEAEAWSPR 16 0 H7C1F0;F8WAB6;D3YTB5;P51617-4;P51617-2;P51617-3;P51617 H7C1F0 IRAK1 Interleukin-1 receptor-associated kinase 1 1 0 PSSIPAPAEAEAWS(1)PR;PSSIPAPAEAEAWS(1)PR ; 176.17 3.41E-16 3395600 4004.1 3434.3 3409.6 3269 3227.5 4520.6 4007.4 2838.8 3131.1 3117.7 TRUE FALSE FALSE 3687.17126 3731.145589 3535.962775 3255.473744 3189.01417 3582.976602 4119.836859 3704.337052 2787.626164 3226.039843 1.142940397 1.156571453 1.096069158 1.009123849 0.988522872 1.11064239 1.277057029 1.148261408 0.864101592 1 11.65554854 PSSLSDNFAAT(ph)AAASGGGLR ddPTM_HeLa_Curcumin_4h_R1 1 PSSLSDNFAATAAASGGGLR 20 0 Q9NU39 Q9NU39 FOXD4L1 Forkhead box protein D4-like 1 1 0 PSSLS(0.156)DNFAAT(0.842)AAAS(0.001)GGGLR 96.756 0.0021635 10812000 3553.4 2385.1 2838.6 3334.6 3340.2 351.39 1037 998.72 3103.8 2604.2 TRUE FALSE FALSE 3272.14464 2591.257416 2943.801013 3320.802309 3300.370297 278.507753 1066.095429 1303.22513 2763.320905 2694.695756 1.214290939 0.961614093 1.092442813 1.232347771 1.224765463 0.103354062 0.395627383 0.483626074 1.025466752 1 11.39590668 -5.266652845 24.9996607 1.109176008 0.334344982 0.888652501 0.126475232 99.62490206 477723.4201 0.01911373 0.043970564 5.41E-06 5.266652845 -0.774831026 PSSRSLTEENSAT(ph)ES(ph)KIASISNS(ph)PRDWR ddPTM_HeLa_Curcumin_4h_R1 1 PSSRSLTEENSATESKIASISNSPRDWR 28 3 H0YNN7;Q9UPX6 H0YNN7 KIAA1024 UPF0258 protein KIAA1024 3 0 PS(0.005)S(0.005)RS(0.005)LT(0.005)EENS(0.015)AT(0.893)ES(0.632)KIAS(0.295)IS(0.419)NS(0.726)PRDWR 42.557 0.0085212 0 0 0 234.93 153.01 0 154.44 0 405.52 135.75 119.28 TRUE FALSE FALSE 0 0 243.6367125 152.3768852 0 122.4074031 0 529.1611812 120.8585646 123.4249711 0 0 1.973966129 1.234570961 0 0.991755574 0 4.287310553 0.979206748 1 6.947490497 -6.772452764 24.9965259 0.475000035 1.258597155 0.119254436 1.179231721 392.7684997 891445.5717 0.182253953 0.240794572 1.69E-07 6.772452764 0.783597121 PSSS(ph)DTALGGGGGLSWAEK ddPTM_HeLa_Curcumin_4h_R1 1 PSSSDTALGGGGGLSWAEK 19 0 Q14004-2;Q14004 Q14004-2 CDK13 Cyclin-dependent kinase 13 1 0 PS(0.008)S(0.056)S(0.925)DT(0.011)ALGGGGGLSWAEK 148.44 4.70E-10 0 620.17 518.01 742.88 623.02 756.86 708.57 701.12 431.94 753.25 660.69 TRUE FALSE FALSE 571.0828901 562.7844762 770.4117863 620.4421083 747.8349388 561.6045948 720.7915402 563.6365176 670.6203595 683.6489283 0.835345258 0.823206843 1.126911422 0.907544915 1.093887386 0.821480985 1.05432995 0.824453158 0.980942603 1 9.417111843 PSSTS(ph)PDQGDDLENCILR ddPTM_HeLa_Curcumin_4h_R1 4 PSSTSPDQGDDLENCILR 18 0 Q5T7X0;Q5T7W7 Q5T7X0 TSTD2 Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 1 0 PSS(0.004)T(0.031)S(0.965)PDQGDDLENCILR;PSS(0.002)T(0.026)S(0.973)PDQGDDLENCILR;PS(0.006)S(0.023)T(0.344)S(0.627)PDQGDDLENCILR;PS(0.003)S(0.003)T(0.06)S(0.934)PDQGDDLENCILR ;;; 181.86 5.83E-07 20750500 3885.1 3077.22 2626.91 3272.63 2703.37 3338.48 2226.48 1507.01 3045.93 3071.13 TRUE FALSE FALSE 3577.590235 3343.201185 2724.265595 3259.088724 2671.134078 2646.041616 2288.949037 1966.490412 2711.7991 3177.851539 1.125788978 1.052031898 0.857266478 1.025563556 0.840547158 0.832651111 0.720281929 0.61881129 0.853343546 1 11.63383601 -4.933239564 0.581081377 1.058265148 0.514903395 0.629721148 0.090819584 0.612228968 0.220011486 0.014493599 0.192492348 1.17E-05 4.933239564 -0.543361753 PSSTTPTPLVS(ph)ETGGNSPSDKVDNELK ddPTM_HeLa_Curcumin_4h_R1 1 PSSTTPTPLVSETGGNSPSDKVDNELK 27 1 A0A3B3IRW6;Q2KHR3-2;Q2KHR3;H0YCQ7 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 0 PS(0.017)S(0.016)T(0.015)T(0.014)PT(0.108)PLVS(0.34)ET(0.271)GGNS(0.198)PS(0.022)DKVDNELK 44.683 0.015736 18070000 1551.2 1148.8 1651.7 1875.3 1971.6 1755.2 1545.6 587.06 1330 1445.2 TRUE FALSE FALSE 1428.420883 1248.097153 1712.913455 1867.540505 1948.089958 1391.151735 1588.965376 766.0518915 1184.102327 1495.420592 0.955196746 0.83461279 1.145439259 1.248839634 1.302703713 0.930274561 1.062554163 0.512265175 0.791818926 1 10.54633559 -4.25849033 24.44035723 1.020478066 0.512264918 0.491535533 0.157744924 129.2447548 1071040.81 0.020750148 0.193397461 5.51E-05 4.25849033 -0.508213148 PSSTTPTPLVSETGGNS(ph)PSDKVDNELK ddPTM_HeLa_Curcumin_4h_R1 1 PSSTTPTPLVSETGGNSPSDKVDNELK 27 1 A0A3B3IRW6;Q2KHR3-2;Q2KHR3;H0YCQ7 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 0 PSSTTPT(0.001)PLVS(0.123)ET(0.169)GGNS(0.663)PS(0.044)DKVDNELK 93.404 2.22E-06 15078000 1986.1 1622.4 1882.3 2356.9 2200.1 1594.5 1970.7 811.53 1340.1 1734.7 TRUE FALSE FALSE 1828.898089 1762.633027 1952.059694 2347.147772 2173.865244 1263.782726 2025.992538 1058.961761 1193.094383 1794.980696 1.018895687 0.981978821 1.087510132 1.307617278 1.211080013 0.704064801 1.128698789 0.589957187 0.664683685 1 10.80975261 -4.253560536 24.64389023 1.031587049 0.589956923 0.299147845 0.191435943 586.8682035 1835586.298 0.020455221 0.296452248 5.58E-05 4.253560536 -0.441630126 PSTQPRPDS(ph)WGEDNWEGLETDSR ddPTM_HeLa_Curcumin_4h_R1 2 PSTQPRPDSWGEDNWEGLETDSR 23 1 H0YDH0;E9PPN3;E9PS17;Q96KG9-3;Q96KG9-2;Q96KG9 H0YDH0 SCYL1 N-terminal kinase-like protein 1 0 PS(0.003)T(0.01)QPRPDS(0.988)WGEDNWEGLETDSR;PSTQPRPDS(1)WGEDNWEGLETDSR ; 153.76 3.97E-07 172296000 2651 2330.5 2644.57 2475.28 2186.09 2376.85 2387.37 1301.12 2422.65 2533.5 TRUE FALSE FALSE 2441.170553 2531.938035 2742.580091 2465.037947 2160.022305 1883.864517 2454.353177 1697.825498 2156.891356 2621.538936 0.931197519 0.965821259 1.046171793 0.940301864 0.823952021 0.718610161 0.936226101 0.647644586 0.822757704 1 11.35619826 -5.742938211 3.399980923 0.972579462 0.782901064 0.471633545 0.087572438 0.117504273 2.838091289 0.010155784 0.020568283 1.81E-06 5.742938211 -0.189678399 VLS(ph)PLRS(ph)PPLIGSESAYESFLSADDK ddPTM_HeLa_Curcumin_4h_R1 1 VLSPLRSPPLIGSESAYESFLSADDK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 VLS(0.772)PLRS(0.848)PPLIGS(0.283)ES(0.034)AY(0.049)ES(0.01)FLS(0.003)ADDK 49.871 0.01538 1349900 187.03 59.119 173.62 184.11 158.61 289.81 290.44 626.05 232.91 304.76 TRUE FALSE FALSE 172.2263781 64.22898293 180.0545099 183.3482016 156.7186793 229.7001392 298.5889647 816.929763 207.3603557 315.3503873 0.54614291 0.203674977 0.57096651 0.581411056 0.496966821 0.728396566 0.946848257 2.590546249 0.657555418 1 8.300811895 -4.243815746 2.92269716 0.687354215 2.962487081 0.893131748 0.204015965 0.132321229 1.544314738 0.037283175 0.71964284 5.70E-05 4.243815746 2.275132866 up PT(ph)T(ph)SETGTPRVEGMVTEK ddPTM_HeLa_Curcumin_4h_R1 1 PTTSETGTPRVEGMVTEK 18 1 P58397-3;P58397 P58397-3 ADAMTS12 A disintegrin and metalloproteinase with thrombospondin motifs 12 2 0 PT(0.725)T(0.725)S(0.252)ET(0.252)GT(0.046)PRVEGMVTEK 51.695 0.0090701 0 257.73 320.02 263.83 575.98 293.9 138.5 259.82 304.32 457.07 266.19 TRUE FALSE FALSE 237.3303985 347.6811028 273.6077719 573.5967474 290.3954345 109.7735388 267.1098499 397.1057671 406.9305645 275.4400827 0.861640747 1.2622749 0.993347697 2.08247377 1.054296207 0.398538723 0.969756643 1.441713796 1.47738325 1 8.105594709 -7.266521932 24.13390116 0.934663687 1.157908392 0 0.435920158 628.3155335 2983477.143 0.069909042 0.081286959 5.41E-08 7.266521932 0.223244705 PT(ph)VY(ph)GVS(ph)PIHDKWEMERTDIT(ph)MK ddPTM_HeLa_Curcumin_4h_R1 1 PTVYGVSPIHDKWEMERTDITMK 23 2 P42684-2;P42684-3;P42684-4;P42684-10;P42684-6;P42684;P42684-7;P42684-5;P42684-8 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 4 0 PT(1)VY(1)GVS(1)PIHDKWEMERT(0.225)DIT(0.775)MK 55.763 0.0029398 2191900 2024.2 1481.1 1642.6 1918.8 1667 1865.1 1459.2 1086.6 1746.2 2039.1 TRUE FALSE FALSE 1863.982434 1609.119684 1703.476201 1910.860514 1647.122114 1478.257236 1500.141225 1417.899338 1554.646229 2109.958573 0.883421342 0.762630937 0.807350544 0.905638878 0.780641921 0.700609602 0.710981364 0.672003401 0.736813627 1 11.04299896 -2.621112862 0.091050639 1.187418127 3.49E-16 0.088640717 0.09448785 28.80959246 0.270237229 0.647988716 4.397706111 0.002392694 2.621112862 -1.187418127 PTLLANGGHGVEGSDT(ph)TGSPTEFLEEK ddPTM_HeLa_Curcumin_4h_R1 1 PTLLANGGHGVEGSDTTGSPTEFLEEK 27 0 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;H7C456;A0A0J9YW37 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 PTLLANGGHGVEGS(0.003)DT(0.878)T(0.101)GS(0.017)PT(0.001)EFLEEK 145.86 2.40E-08 7115600 834.86 820.24 611.33 668.64 830.9 954.28 749.75 622.48 711.95 617.57 TRUE FALSE FALSE 768.7799501 891.1378907 633.9864276 665.8733448 820.9920602 756.351571 770.7859672 812.2712865 633.8508662 639.0305115 1.20304107 1.394515402 0.992106662 1.042005558 1.284746261 1.183592266 1.206180227 1.271099379 0.991894526 1 9.319741006 -9.131396286 0.857260752 0.997768171 1.193688116 0.346321039 0.109467775 0.620614275 0.813185586 0.07700858 0.021609434 7.39E-10 9.131396286 0.195919945 PTLLANGGHGVEGSDTTGS(ph)PTEFLEEK ddPTM_HeLa_Curcumin_4h_R1 1 PTLLANGGHGVEGSDTTGSPTEFLEEK 27 0 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;H7C456;A0A0J9YW37 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 PTLLANGGHGVEGS(0.044)DT(0.044)T(0.188)GS(0.566)PT(0.157)EFLEEK 59.426 0.0017571 4972600 1447.5 1009.7 1081.6 1125.8 1228.9 1330.6 1266.5 1015.6 1110.5 1284.4 TRUE FALSE FALSE 1332.928848 1096.973969 1121.685047 1121.141738 1214.24617 1054.618561 1302.034581 1325.251765 988.6809283 1329.032804 1.002931488 0.825392696 0.843985975 0.843577174 0.913631451 0.793523348 0.979685811 0.997155044 0.743910101 1 10.376161 -7.280190359 24.04657725 1.001384323 0.883279166 0 0.101984145 336.6802372 431763.3812 0.010608742 0.01214438 5.25E-08 7.280190359 -0.118105157 PTRTSSESIY(ph)S(ph)RPGSSIPGS(ph)PGHT(ph)IYAK ddPTM_HeLa_Curcumin_4h_R1 1 PTRTSSESIYSRPGSSIPGSPGHTIYAK 28 2 F8W8M4;O14639-3;O14639-2;O14639;A0A494C1P1;A0A494C1G0;H0Y7N6;F6XFR5 F8W8M4 ABLIM1 Actin-binding LIM protein 1 4 0 PT(0.009)RT(0.009)S(0.009)S(0.009)ES(0.045)IY(0.755)S(0.762)RPGS(0.36)S(0.36)IPGS(0.75)PGHT(0.746)IY(0.185)AK 47.807 0.0065254 0 633.43 385.33 498.35 513.92 496.99 740.16 645.76 315.65 748.42 828.34 TRUE FALSE FALSE 583.2933471 418.6362082 516.8192894 511.7935352 491.0637188 586.6424727 663.8782876 411.8902319 666.3201985 857.1247533 0.680523278 0.488419226 0.602968573 0.597105069 0.572919773 0.684430674 0.774541028 0.480548754 0.777389984 1 9.743361392 -8.712415138 0.717848259 0.995028179 0.609042685 0.488361594 0.105999431 0.254506333 0.256664487 0.051389015 0.019574466 1.94E-09 8.712415138 -0.385985494 S(ph)DSASSEPVGIYQGFEK ddPTM_HeLa_Curcumin_4h_R1 1 SDSASSEPVGIYQGFEK 17 0 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 0 S(0.982)DS(0.003)AS(0.015)SEPVGIYQGFEK 237.34 4.70E-70 0 2318.3 1565.8 1957 1906.2 1886.3 2362 2071.4 2542.8 1777.5 1579.4 TRUE FALSE FALSE 2134.804109 1701.140775 2029.528142 1898.312649 1863.807104 1872.094575 2129.517909 3318.088014 1582.512697 1634.284032 1.3062626 1.040908888 1.241845421 1.161556138 1.140442584 1.145513593 1.303028034 2.0303007 0.968321703 1 10.67444302 -4.243538793 2.617782368 1.148153362 2.234803014 0.879023768 0.100120312 0.145229469 1.229565767 0.016002713 0.351180471 5.71E-05 4.243538793 1.086649652 up PVIVEPLEQLDDEDGLPEK ddPTM_HeLa_Curcumin_4h_R1 1 PVIVEPLEQLDDEDGLPEK 19 0 P23246;P23246-2 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 0 88.264 0.0019421 2464900 3335.5 2630.2 3463.1 3336.7 3216.2 2921.1 3059.8 2696.3 2528.2 2888 FALSE FALSE TRUE 3071.491655 2857.542768 3591.445532 3322.89362 3177.848916 2315.230932 3145.649753 3518.389458 2250.862785 2988.357785 1.027819249 0.956225115 1.20181243 1.111946379 1.063409787 0.774750247 1.052634918 1.177365533 0.753210608 1 11.54513717 -4.304824241 4.810353734 1.017622284 1.181375831 0.126769948 0.133606796 0.219042002 11.45134897 0.014092374 0.101155452 4.96E-05 4.304824241 0.163753547 PVS(ph)RT(ph)ARS(ph)T(ph)GPWR ddPTM_HeLa_Curcumin_4h_R1 1 PVSRTARSTGPWR 13 2 I3L1S7 I3L1S7 ZSCAN32 4 0 PVS(1)RT(1)ARS(1)T(1)GPWR 72.891 0.010804 8370000 1561.9 1717.6 1418.6 1707.3 1777 1979.1 1946.2 1875.8 1971.6 1944.5 TRUE FALSE FALSE 1438.273967 1866.061691 1471.174564 1700.235645 1755.810436 1568.612351 2000.805134 2447.722785 1755.320413 2012.07123 0.714822589 0.927433215 0.731174196 0.845017621 0.872638309 0.779600805 0.994400747 1.216518952 0.872394767 1 10.97446566 -4.404050646 2.854926193 0.852149511 1.232282456 0.658031558 0.083001641 0.201424676 2.608752533 0.015575071 0.148093732 3.94E-05 4.404050646 0.380132944 PVS(ph)SAASVYAGAGGSGSR ddPTM_HeLa_Curcumin_4h_R1 2 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 PVS(0.629)S(0.37)AAS(0.002)VYAGAGGSGSR;PVS(0.985)S(0.015)AASVYAGAGGSGSR ; 221.34 2.47E-17 87495000 1536.21 1051.99 1748.08 1534.24 1361.27 1513.05 1519.65 774.23 1352.94 1413.37 TRUE FALSE FALSE 1414.617357 1142.919328 1812.865383 1527.891721 1345.037744 1199.226374 1562.287289 1010.289163 1204.525867 1462.484502 0.967269982 0.781491582 1.239579209 1.044723359 0.919693673 0.819992535 1.068241945 0.690803329 0.823616158 1 10.51420562 -4.250127868 23.96235905 0.980625115 0.690803021 0.268780329 0.131612203 805.266187 1705821.116 0.015777472 0.313337268 5.62E-05 4.250127868 -0.289822094 PVS(ph)VAGSPLSPGPVR ddPTM_HeLa_Curcumin_4h_R1 1 PVSVAGSPLSPGPVR 15 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 PVS(0.995)VAGS(0.003)PLS(0.002)PGPVR 150.9 0.0004353 19384000 2096.5 1955.7 1553.9 1989 2036.3 1913 1950.5 1032.9 1788.8 1558.3 TRUE FALSE FALSE 1930.559813 2124.741994 1611.488901 1980.770045 2012.018452 1516.222236 2005.22578 1347.826455 1592.573115 1612.450809 1.19728292 1.317709651 0.99940345 1.228421998 1.247801447 0.940321545 1.243588809 0.835886867 0.987672372 1 10.65503943 -4.244697195 24.08962621 1.120274854 0.835886495 0.314544457 0.12927431 1943.837226 2796832.551 0.017522008 0.617250004 5.69E-05 4.244697195 -0.284388359 PVSPS(ph)SLLDTAISEEAR ddPTM_HeLa_Curcumin_4h_R1 1 PVSPSSLLDTAISEEAR 17 0 A0A0B4J2F2;P57059 A0A0B4J2F2 LOC102724428;SIK1 Serine/threonine-protein kinase SIK1 1 0 PVS(0.356)PS(0.643)S(0.002)LLDTAISEEAR 252.1 2.32E-40 91028000 398.66 308.15 414.22 429.32 423.67 736.73 373.23 0 390.72 327.5 TRUE FALSE FALSE 367.1056403 334.7851129 429.5713576 427.5435876 418.618012 583.9238933 383.7018293 0 347.8589935 338.8806006 1.083289039 0.987914659 1.267618615 1.261634885 1.235296477 1.723096254 1.132262598 0 1.026494266 1 8.404633241 PVSSAASVYAGAGGS(ph)GSR ddPTM_HeLa_Curcumin_4h_R1 3 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 PVSSAASVYAGAGGS(0.707)GS(0.293)R;PVSSAASVYAGAGGS(0.975)GS(0.025)R;PVSSAASVYAGAGGS(0.989)GS(0.011)R ;; 192.72 5.76E-09 325615000 7070.6 5201.8 5472.4 6240.6 6133.3 8139 6444.7 2975.9 5594.3 6030.5 TRUE FALSE FALSE 6510.954549 5651.420413 5675.211958 6214.778051 6060.164403 6450.879655 6625.520937 3883.238211 4980.619286 6240.059426 1.043412267 0.905667723 0.909480434 0.995948536 0.971170944 1.033784971 1.06177209 0.622307889 0.798168566 1 12.60734405 -4.256118332 24.97462985 1.003849126 0.622307727 0.588611903 0.082347499 177.3779791 832506.763 0.007644488 0.087150594 5.54E-05 4.256118332 -0.381541399 PVSSAASVYAGAGGSGSR ddPTM_HeLa_Curcumin_4h_R1 2 PVSSAASVYAGAGGSGSR 18 0 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 0 0 ; ; 303.7 1.91E-132 10405000 1099.91 1054.94 1090.43 1128.03 942.47 917.6 1119.55 657.71 1052.04 1150.89 FALSE FALSE TRUE 1012.850963 1146.124313 1130.842295 1123.362511 931.2316608 727.2794165 1150.96156 858.2427513 936.6338441 1190.883342 0.85050393 0.96241527 0.949582764 0.943301893 0.781967157 0.610705844 0.966477168 0.720677434 0.786503439 1 10.21781638 -5.747972432 8.544369738 0.933093708 0.772305125 0.326948492 0.100294117 0.12775191 58.46149802 0.013542281 0.026423683 1.79E-06 5.747972432 -0.160788582 PVSVAGS(ph)PLSPGPVR ddPTM_HeLa_Curcumin_4h_R1 1 PVSVAGSPLSPGPVR 15 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 PVS(0.002)VAGS(0.582)PLS(0.416)PGPVR 135.86 0.00061334 16577000 1987 1449.6 1776.5 1594.5 1669.7 2132.2 2128.2 746.21 1794.8 1615.2 TRUE FALSE FALSE 1829.726853 1574.896965 1842.338653 1587.902381 1649.789918 1689.957685 2187.911564 973.7259939 1597.91493 1671.32808 1.094774195 0.942302702 1.10232017 0.950084188 0.987113146 1.011146588 1.309085625 0.582606136 0.956074962 1 10.70677925 -4.238356506 24.73134756 1.043417656 0.582605541 0.631613231 0.10456927 2600.058824 2785696.392 0.012951353 0.986511643 5.78E-05 4.238356506 -0.460812115 ELDFSS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 1 ELDFSSPGR 9 0 Q4AC94;Q4AC94-2;Q4AC94-4;Q4AC94-1;Q4AC94-3;H0YG44;H7C288;H7BZB4 Q4AC94 C2CD3 C2 domain-containing protein 3 1 0 ELDFS(0.028)S(0.972)PGR 104.42 0.010951 5972200 7275.5 5935.2 6781.5 6225.9 7005.4 7518.1 4567.9 1422.5 6067.2 5822.6 TRUE FALSE FALSE 6699.636498 6448.212241 7032.828356 6200.138875 6921.86518 5958.761314 4696.06298 1856.213702 5401.643339 6024.934917 1.111984875 1.070254257 1.167287025 1.029079809 1.148869702 0.989016711 0.77943796 0.30808859 0.896547998 1 12.55672994 -4.290947613 1.620404037 1.0682963 0.057467938 0.90402295 0.074721794 0.158565371 0.408440274 0.008682239 0.24647057 5.12E-05 4.290947613 -1.010828362 down PYECK(ac)ECGK(ac)TFCQK ddPTM_HeLa_Curcumin_4h_R1 1 PYECKECGKTFCQK 14 2 C9JVC3;A0A494C0W3;Q9BY31 C9JVC3 ZNF717 Zinc finger protein 717 0 2 PYECK(1)ECGK(1)TFCQK 50.897 0.01584 0 727 512.39 696.78 424.04 706.71 962.96 654.27 503.32 567.34 472.38 FALSE TRUE FALSE 669.4571829 556.6787084 722.6032798 422.2854348 698.2829448 763.2312412 672.6270553 656.779951 505.1042214 488.7951698 1.369606789 1.138879315 1.478335557 0.863931276 1.428579879 1.561454139 1.376091862 1.343671115 1.03336582 1 8.933086219 -12.31273678 0.240530573 9.21E-13 1.373429009 0.318303655 0.182757004 24.59427611 0.536981568 11.91715668 0.125964211 4.87E-13 12.31273678 1.373429009 PYKCEECGKAFNQS(ph)S(ph)T(ph)LS(ph)IHKIIHTGEK ddPTM_HeLa_Curcumin_4h_R1 1 PYKCEECGKAFNQSSTLSIHKIIHTGEK 28 3 Q6ZR52;Q6ZR52-2 Q6ZR52 ZNF493 Zinc finger protein 493 4 0 PY(0.267)KCEECGKAFNQS(0.872)S(0.877)T(0.983)LS(0.973)IHKIIHT(0.029)GEK 40.112 0.015423 84487000 1428.3 1537.3 1514.4 1813.1 1615.3 1706.8 1837.5 1699 1705.4 1751.3 TRUE FALSE FALSE 1315.248548 1670.177362 1570.524996 1805.597873 1596.038602 1352.79044 1889.055305 2217.017279 1518.321887 1812.157545 0.725791503 0.921651303 0.866660297 0.996380187 0.88073943 0.746508185 1.042434368 1.2234131 0.837853139 1 10.82349267 -4.510840977 4.254386221 0.874353415 1.196641474 0.62359419 0.086344117 0.124589345 5.254672963 0.015564369 0.082662795 3.08E-05 4.510840977 0.322288059 PYQYPALT(ph)PEQK ddPTM_HeLa_Curcumin_4h_R1 1 PYQYPALTPEQK 12 0 P04075;H3BQN4;J3KPS3;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 0 PY(0.001)QYPALT(0.999)PEQK 133.47 0.0058691 15024000 4311 3737.1 4154.9 4099.9 3752.6 4163.5 3711.6 2987.4 3338.9 4060.9 TRUE FALSE FALSE 3969.779801 4060.118272 4308.884249 4082.9357 3707.852696 3299.943168 3815.737507 3898.244508 2972.631024 4202.015973 0.944732202 0.966231042 1.02543262 0.971661157 0.882398525 0.785323804 0.908073061 0.92770816 0.70742973 1 12.03686593 -5.74893045 5.310528096 0.977002776 0.870680517 0 0.094164697 0.095528435 7.79346375 0.006273844 0.012279803 1.78E-06 5.74893045 -0.106322259 PYQYPALT(ph)PEQKK ddPTM_HeLa_Curcumin_4h_R1 2 PYQYPALTPEQKK 13 1 P04075;H3BQN4;J3KPS3;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 1 0 PYQYPALT(1)PEQKK;PYQY(0.004)PALT(0.996)PEQKK ; 72.433 0.016864 51257000 7462.6 5231.3 5449 5511 4395.8 6007.9 4973 4539.1 6000.3 7173.5 TRUE FALSE FALSE 6871.927336 5683.470262 5650.944733 5488.196942 4343.382956 4761.793817 5112.528996 5923.050695 5342.082102 7422.778591 0.925789076 0.765679616 0.761297763 0.739372308 0.585142464 0.64151096 0.688762157 0.797955997 0.719687653 1 12.85774362 -7.147636421 1.008608085 0.979608711 0.680686076 0.286374819 0.099322533 0.132697469 0.264833988 0.012280509 0.015474276 7.12E-08 7.147636421 -0.298922635 PYQYPALTPEQK ddPTM_HeLa_Curcumin_4h_R1 1 PYQYPALTPEQK 12 0 P04075;H3BQN4;J3KPS3;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 173.71 5.78E-07 8444200 2876.4 1817.7 2170.3 2206 1829.9 2323.8 2036.9 1543.4 1751.8 2261.4 FALSE FALSE TRUE 2648.729905 1974.813888 2250.733227 2196.872157 1808.079638 1841.817685 2094.049932 2013.975555 1559.631923 2339.983482 1.131943847 0.843943517 0.961858596 0.938840882 0.77268906 0.787107131 0.894899451 0.86067939 0.666514074 1 11.19228263 -7.252950317 24.98855213 1.062306817 0.866748041 0 0.140059237 313.1903639 921913.175 0.012597839 0.015294085 5.59E-08 7.252950317 -0.195558777 PYQYPALTPEQK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 PYQYPALTPEQKK 13 1 P04075;H3BQN4;J3KPS3;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 1 ; PYQYPALTPEQK(1)K;PYQYPALTPEQK(1)K 213.63 1.13E-21 6812500 4978.8 3733.7 3679.8 3533.8 4096.6 5985.3 4913.7 5028.9 7497 4477.7 FALSE TRUE FALSE 4584.722726 4056.424391 3816.176625 3519.178072 4047.750721 4743.881312 5051.565197 6562.18846 6674.597857 4633.299742 0.989515676 0.875493626 0.823641214 0.759540342 0.873621597 1.023866699 1.090273774 1.416309936 1.440571133 1 12.1778243 -4.227071291 1.662477806 0.948795316 1.608306076 0.361074993 0.176589452 0.505115709 1.241986592 0.014850425 0.545674884 5.93E-05 4.227071291 0.659510761 PYQYPALTPEQKK ddPTM_HeLa_Curcumin_4h_R1 1 PYQYPALTPEQKK 13 1 P04075;H3BQN4;J3KPS3;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 131.32 0.00036678 4704900 2877 1817.8 1665.9 1608.2 1759.2 2086.1 1941.9 1816 2783 2959.8 FALSE FALSE TRUE 2649.282414 1974.922532 1727.639719 1601.545695 1738.222689 1653.419345 1996.384488 2369.69004 2477.711863 3062.65283 0.865028641 0.644840484 0.564099105 0.5229276 0.567554596 0.53986509 0.651848119 0.773737727 0.809008399 1 11.58056612 -7.374423498 1.699015987 0.951795613 0.594654922 0.694591087 0.084275264 0.106064523 0.586849392 0.015333352 0.017416101 4.22E-08 7.374423498 -0.357140691 PYS(ph)NVSNLK ddPTM_HeLa_Curcumin_4h_R1 1 PYSNVSNLK 9 0 O95248;O95248-5;O95248-4 O95248 SBF1 Myotubularin-related protein 5 1 0 PY(0.151)S(0.849)NVSNLK 72.325 0.020059 12925000 725.77 550.14 681.24 479.43 460.26 828.94 484.89 438.85 687.33 487.58 TRUE FALSE FALSE 668.3245387 597.6916502 706.4873537 477.4462457 454.7717001 657.0084999 498.4947084 572.6533448 611.9316186 504.5233687 1.324665179 1.184665939 1.400306502 0.946331281 0.901388773 1.302236013 0.988050781 1.135038296 1.212890535 1 8.978777284 -6.20102798 24.9999671 1.176900533 1.056156274 0.223070455 0.145541996 451.1048746 186679.5177 0.025711879 0.042638325 6.29E-07 6.20102798 -0.120744259 QAAPPIELDAVWEDIRER ddPTM_HeLa_Curcumin_4h_R1 2 QAAPPIELDAVWEDIRER 18 1 O75400-2;O75400-3;O75400 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 0 0 ; ; 176.44 9.09E-07 7265400 4013.3 3456.6 3581.3 3985 3453.7 4570.9 3350.1 3399.8 4120.6 3573.7 FALSE FALSE TRUE 3695.64307 3755.373102 3714.026128 3968.511126 3412.516883 3622.843815 3444.09479 4436.383369 3668.580489 3697.885809 0.999393508 1.015545989 1.004364743 1.073183795 0.922829168 0.979706784 0.931368616 1.199708049 0.992075115 1 11.85248496 -4.249944151 24.88215578 0.996095182 1.199708177 0.705711031 0.040320816 669.386751 1448902.852 0.005234968 0.110752238 5.62E-05 4.249944151 0.203612995 QAAS(ph)PLEPK ddPTM_HeLa_Curcumin_4h_R1 2 QAASPLEPK 9 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;Q14980-4;Q14980-3;F5H6Y5;F5H4J1 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 QAAS(1)PLEPK;QAAS(1)PLEPK ; 107.34 0.010008 100270000 17885.8 14542.8 16443.9 16749.8 17135.2 19130.9 18820.2 24053 17066.3 15362.9 TRUE FALSE FALSE 16470.12006 15799.81483 17053.3254 16680.49377 16930.87393 15162.93569 19348.24416 31386.64897 15194.16959 15896.75963 1.036067755 0.9939016 1.072754813 1.049301502 1.065051893 0.953838143 1.217118747 1.974405458 0.95580294 1 13.9564451 -4.27194192 2.773765898 1.022313146 2.140508768 0.979419827 0.041583204 0.033215777 0.350609047 0.004880545 0.083225724 5.35E-05 4.27194192 1.118195621 QAASGLVGQENAR ddPTM_HeLa_Curcumin_4h_R1 1 QAASGLVGQENAR 13 0 Q9Y265;Q9Y265-2 Q9Y265 RUVBL1 RuvB-like 1 0 0 94.122 0.014154 1080500 79.381 160.9 0 166.75 64.387 0 163.58 0 153.07 84.038 FALSE FALSE TRUE 73.09791009 174.807479 0 166.0600327 63.61922708 0 168.1696145 0 136.278604 86.95831424 0.840608638 2.01024457 0 1.909651011 0.73160603 0 1.933910702 0 1.56717164 1 6.442252068 -5.564079978 24.9993523 1.010842712 0.705597555 0.076199487 0.753097039 399.9819236 242692.7731 0.094774224 0.189548608 2.73E-06 5.564079978 -0.305245157 QAASSLQQASLK ddPTM_HeLa_Curcumin_4h_R1 2 QAASSLQQASLK 12 0 P38646 P38646 HSPA9 "Stress-70 protein, mitochondrial" 0 0 ; ; 190.66 6.02E-14 4292400 1133.55 922.15 873.12 1109.96 1091.19 1939.22 1246.63 952.65 947.36 822.84 FALSE FALSE TRUE 1043.828321 1001.856537 905.4785953 1105.36728 1078.178272 1537.003912 1281.607083 1243.1086 843.4369782 851.4336288 1.225965579 1.176670152 1.063475255 1.298242449 1.266309241 1.805195215 1.505234277 1.460018206 0.990608017 1 9.733750263 -5.634750364 2.001828333 1.116740374 1.577173779 0.72249408 0.12709775 0.134254797 1.084731477 0.019892059 0.047474278 2.32E-06 5.634750364 0.460433406 QADLYISEGLHPR ddPTM_HeLa_Curcumin_4h_R1 1 QADLYISEGLHPR 13 0 P40227;Q92526;Q92526-3 P40227 CCT6A;CCT6B T-complex protein 1 subunit zeta;T-complex protein 1 subunit zeta-2 0 0 179.5 0.00012909 6050100 6451.3 5602.4 5962.6 5645.6 6900.3 11045 6309.6 6080.2 7655.9 5637.3 FALSE FALSE TRUE 5940.672798 6086.646492 6183.579201 5622.240003 6818.018429 8754.142497 6486.630395 7934.02499 6816.066924 5833.195755 1.01842507 1.043449722 1.06006715 0.963835304 1.168830726 1.500745537 1.112020009 1.360150649 1.168496174 1 12.51007077 -5.544732882 5.337208319 1.014342568 1.308830737 0.587727563 0.103960961 0.066669994 5.482104797 0.011883579 0.024771535 2.85E-06 5.544732882 0.294488169 QADPQPQAWPPPDS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 2 QADPQPQAWPPPDSPVR 17 0 K7ERU2;Q63ZY3-3;Q63ZY3;Q63ZY3-2 K7ERU2 KANK2 KN motif and ankyrin repeat domain-containing protein 2 1 0 QADPQPQAWPPPDS(1)PVR;QADPQPQAWPPPDS(1)PVR ; 201.14 1.64E-10 18166000 2834.8 2740.5 2644.1 2407.2 3219.9 3095.9 2557.5 1954.56 2874.9 2424.78 TRUE FALSE FALSE 2610.422589 2977.376609 2742.092672 2397.239644 3181.504795 2453.775442 2629.256567 2550.496346 2559.530663 2509.040925 1.040406541 1.186659245 1.092884793 0.955440631 1.268016302 0.977973463 1.047912986 1.016522418 1.020123123 1 11.29292029 -7.627873255 3.668308379 1.015849727 1.077994076 0.082908704 0.088634375 0.375151018 10.63493868 0.01548078 0.016208033 2.36E-08 7.627873255 0.062144349 QADPQPQAWPPPDS(ph)PVRVDTVR ddPTM_HeLa_Curcumin_4h_R1 2 QADPQPQAWPPPDSPVRVDTVR 22 1 K7ERU2;Q63ZY3-3;Q63ZY3;Q63ZY3-2 K7ERU2 KANK2 KN motif and ankyrin repeat domain-containing protein 2 1 0 QADPQPQAWPPPDS(0.526)PVRVDT(0.474)VR;QADPQPQAWPPPDS(0.989)PVRVDT(0.011)VR ; 137.85 1.22E-05 162713000 6063 4807 5233.2 5560.7 5625.3 7249.9 5651.1 4097.4 6289.7 5853.9 TRUE FALSE FALSE 5583.107152 5222.49566 5427.146996 5537.691297 5558.221972 5746.189017 5809.654657 5346.678398 5599.735646 6057.322589 0.921712039 0.862178889 0.895964664 0.91421436 0.917603758 0.948635132 0.959112639 0.882680148 0.924457227 1 12.56446453 -8.859892333 0.870770669 0.996767661 0.914411725 0.121100436 0.035146734 0.325666349 0.478024591 0.015417817 0.005944421 1.38E-09 8.859892333 -0.082355936 QAEEECAHRGS(ph)PLPK ddPTM_HeLa_Curcumin_4h_R1 1 QAEEECAHRGSPLPK 15 1 F2Z2A4;H7C1J2;H7C1M5;Q9H147 F2Z2A4 DNTTIP1 Deoxynucleotidyltransferase terminal-interacting protein 1 1 0 QAEEECAHRGS(1)PLPK 63.894 0.017197 38491000 3126.8 2869.2 2832.2 2551.6 2903 3469.8 2869.9 901.04 3472.7 2754.9 TRUE FALSE FALSE 2879.310481 3117.200863 2937.163823 2541.042155 2868.383621 2750.124367 2950.42167 1175.762948 3091.753498 2850.63257 1.010060192 1.093511979 1.030355106 0.891395889 1.006227057 0.96474179 1.03500595 0.412456856 1.08458506 1 11.47706638 -4.259607126 24.99730743 1.003850481 0.412456657 0.913985568 0.055195094 28.36153115 386902.5841 0.006564762 0.05695309 5.50E-05 4.259607126 -0.591393824 QAEILQESR ddPTM_HeLa_Curcumin_4h_R1 1 QAEILQESR 9 0 E5RIW3;E5RJD8;O75347;O75347-2 E5RIW3 TBCA Tubulin-specific chaperone A 0 0 107.45 0.0044522 4171700 1932.9 1584.4 1597.1 1589.3 1766.7 1952.6 1392 1603 1835.9 1633.1 FALSE FALSE TRUE 1779.908925 1721.348476 1656.289931 1582.723898 1745.633256 1547.60875 1431.055774 2091.747321 1634.506363 1689.850103 1.053293971 1.018639744 0.980140148 0.93660609 1.033010711 0.915826053 0.846853677 1.237830099 0.96724932 1 10.72267956 -6.800793613 5.264617224 1.025603204 0.980972726 0 0.098857701 0.50285237 33.20796279 0.014578184 0.019562137 1.58E-07 6.800793613 -0.044630478 QAEVANQETKEDLPAENGETKTEESPAS(ph)DEAGEKEAK ddPTM_HeLa_Curcumin_4h_R1 1 QAEVANQETKEDLPAENGETKTEESPASDEAGEKEAK 37 3 P05114;A6NL93;A6NEL0 P05114 HMGN1 Non-histone chromosomal protein HMG-14 1 0 QAEVANQET(0.001)KEDLPAENGET(0.071)KT(0.071)EES(0.155)PAS(0.701)DEAGEKEAK 41.914 0.0059674 27129000 2631 1674.8 1984.2 2483.4 2614.4 2823.9 2605.4 2399.2 3354.6 2887.5 TRUE FALSE FALSE 2422.753574 1819.562249 2057.736197 2473.124349 2583.224988 2238.191308 2678.500512 3130.705035 2986.608773 2987.84041 0.810871145 0.608989102 0.688703517 0.827729734 0.864579306 0.749100019 0.896467061 1.047815347 0.999587783 1 11.54488738 -8.946339966 1.005192603 0.989184978 0.807523571 0.301147347 0.112991419 0.512607942 1.007186812 0.05718561 0.0227323 1.13E-09 8.946339966 -0.181661407 QAGAPGGSSGSGGS(ph)PELSALR ddPTM_HeLa_Curcumin_4h_R1 3 QAGAPGGSSGSGGSPELSALR 21 0 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 0 QAGAPGGSSGS(0.001)GGS(0.933)PELS(0.065)ALR;QAGAPGGSSGS(0.005)GGS(0.878)PELS(0.116)ALR;QAGAPGGS(0.01)S(0.001)GSGGS(0.969)PELS(0.019)ALR ;; 232.87 1.57E-29 64997000 8998.8 6993.2 7294.8 7844.1 7600.4 9188.8 8675.1 4502.6 8371.2 7140.1 TRUE FALSE FALSE 8286.535485 7597.661047 7565.151705 7811.643193 7509.770194 7282.939301 8918.499958 5875.422013 7452.900304 7388.217944 1.121587851 1.028348257 1.023948097 1.057310877 1.016452174 0.985750469 1.207124644 0.795242108 1.008754799 1 12.85101071 -4.237348851 24.43377082 1.054286577 0.795241692 0.588842016 0.063749609 2980.14885 3022549.195 0.008921737 0.749752217 5.79E-05 4.237348851 -0.259044885 QAGAPGGSSGSGGSPELS(ph)ALR ddPTM_HeLa_Curcumin_4h_R1 1 QAGAPGGSSGSGGSPELSALR 21 0 Q9Y2J4;Q9Y2J4-2;Q9Y2J4-4 Q9Y2J4 AMOTL2 Angiomotin-like protein 2 1 0 QAGAPGGS(0.001)S(0.002)GS(0.006)GGS(0.095)PELS(0.897)ALR 118.44 1.32E-05 10062000 2412.5 1990.7 1863.4 1787 1922.6 2836.6 1693.7 1093.5 2116.9 1988.2 TRUE FALSE FALSE 2221.548079 2162.767238 1932.459243 1779.605867 1899.674251 2248.257185 1741.220664 1426.903116 1884.681366 2057.289802 1.07984207 1.051270091 0.939322813 0.865024396 0.923386802 1.092824736 0.846366254 0.693583915 0.916099115 1 11.00652932 -3.572093236 0.791623274 1.021814788 6.84E-60 0.491682649 0.082790873 3.411746434 0.712410328 0.013403325 3.98240205 0.000267859 3.572093236 -1.021814788 QAGEVTYADAHK ddPTM_HeLa_Curcumin_4h_R1 1 QAGEVTYADAHK 12 0 Q08170;A0A0D9SEM4;Q13247-3;Q13247;A0A590UJK4;A0A590UK01;A0A590UJP7;A0A590UK80 Q08170;Q13247-3 SRSF4;SRSF6 Serine/arginine-rich splicing factor 4;Serine/arginine-rich splicing factor 6 0 0 118.24 0.0029897 3583600 3133.1 2447.6 2951.6 3258.2 3732.7 3709.3 2888.1 2891.8 2680.9 2646.9 FALSE FALSE TRUE 2885.111829 2659.159638 3060.988892 3244.718432 3688.18999 2939.949368 2969.132313 3773.496508 2386.811977 2738.879578 1.053391267 0.970893229 1.117606235 1.184688242 1.346605386 1.073413154 1.084068222 1.377751887 0.871455611 1 11.41937012 -6.479318861 3.07522935 1.021990057 1.205266942 0.51679432 0.104694647 0.170961224 3.239850826 0.014308089 0.021961076 3.32E-07 6.479318861 0.183276885 QAGPAPAAATAASK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 QAGPAPAAATAASKK 15 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 0 1 ; QAGPAPAAATAASK(1)K;QAGPAPAAATAASK(1)K 226.23 7.99E-37 29895000 6045.5 6324.5 6135.7 4671.8 4986.4 7629.6 5304.1 4435.2 5926.4 6037.3 FALSE TRUE FALSE 5566.992296 6871.161599 6363.09444 4652.469329 4926.940437 6047.134957 5452.918771 5787.472063 5276.288747 6247.095726 0.891132862 1.09989696 1.018568423 0.744741162 0.788676955 0.967991403 0.872872613 0.926426025 0.844598671 1 12.60896992 -6.287505545 24.98541552 0.965811014 0.862870273 0.283927314 0.087663855 806.1101176 772685.5652 0.013438428 0.02053159 5.16E-07 6.287505545 -0.102940741 QAGPASVPLRTEEEFK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 QAGPASVPLRTEEEFKK 17 2 P30101 P30101 PDIA3 Protein disulfide-isomerase A3 0 1 QAGPASVPLRTEEEFK(1)K 98.508 0.0020144 4212500 77.929 442.11 279.9 138.66 429.81 783.12 417.41 319.23 527.38 319.88 FALSE TRUE FALSE 71.76083742 480.3240184 290.2733402 138.0862617 424.6847965 620.6920844 429.1214012 416.5617574 469.5277334 330.9958062 0.21680286 1.451148351 0.876969843 0.417184324 1.283051895 1.875226431 1.296455705 1.258510681 1.418530763 1 8.370669128 -5.62125739 5.691162067 0.6984858 1.477095332 0.209320663 0.419728268 0.148887665 7.185802504 0.060396878 0.122155269 2.39E-06 5.62125739 0.778609532 QAHDLS(ph)PAAESSSTFSFSGR ddPTM_HeLa_Curcumin_4h_R1 4 QAHDLSPAAESSSTFSFSGR 20 0 O95425-3;A0A6I8PIX7;O95425-2;O95425;O95425-4 O95425-3 SVIL Supervillin 1 0 QAHDLS(1)PAAESSSTFSFSGR;QAHDLS(1)PAAESSSTFSFSGR;QAHDLS(1)PAAESSSTFSFSGR;QAHDLS(0.913)PAAES(0.031)S(0.022)S(0.022)T(0.009)FS(0.003)FSGR ;;; 203.23 1.06E-13 148659000 10079.4 8363.1 7465.39 8159.86 10136.7 12530.7 9195.49 8638.43 10932.4 8649.99 TRUE FALSE FALSE 9281.604854 9085.969099 7742.063921 8126.096661 10015.82647 9931.69157 9453.490701 11272.24754 9733.143072 8950.576509 1.036984025 1.015126689 0.864979358 0.90788528 1.119014676 1.109614734 1.056187911 1.259387876 1.087431973 1 13.12776489 -2.32232979 0.703443422 1.003862379 4.952630947 0.508647221 0.0740925 22.46368704 0.815480169 0.01216732 124.0388782 0.004760693 2.32232979 3.948768568 QAHDLSPAAES(ph)SSTFSFSGR ddPTM_HeLa_Curcumin_4h_R1 1 QAHDLSPAAESSSTFSFSGR 20 0 O95425-3;A0A6I8PIX7;O95425-2;O95425;O95425-4 O95425-3 SVIL Supervillin 1 0 QAHDLS(0.055)PAAES(0.388)S(0.388)S(0.131)T(0.027)FS(0.009)FS(0.001)GR 66.784 0.0078647 11436000 1350 878.79 1050.6 1274.1 1385.9 1661.3 1157.8 1503.2 1920.8 1470.9 TRUE FALSE FALSE 1243.146075 954.7486918 1089.53616 1268.828112 1369.374048 1316.727653 1190.284752 1961.51876 1710.093046 1522.013666 0.81677721 0.627293114 0.715851759 0.833650933 0.899712058 0.865122097 0.782046035 1.288765538 1.123572728 1 10.5717656 -4.254581068 24.5896618 0.863577461 1.288765786 0.493970202 0.132250962 422.3862128 1514365.405 0.017877161 0.233732572 5.56E-05 4.254581068 0.425188325 QALDS(ph)EEEEEDVAAKETLLR ddPTM_HeLa_Curcumin_4h_R1 1 QALDSEEEEEDVAAKETLLR 20 1 Q8NC44;H7C3D5 Q8NC44 FAM134A Protein FAM134A 1 0 QALDS(1)EEEEEDVAAKETLLR 93.812 0.00040079 7813500 1090 765.09 567.6 904.25 485.69 1104.6 562.4 383.34 1210.7 1207.4 TRUE FALSE FALSE 1003.72535 831.2209704 588.6357553 900.5084531 479.898464 875.4935086 578.1794304 500.2186013 1077.889239 1249.35706 0.803393507 0.665318984 0.471150942 0.720777496 0.384116342 0.700755242 0.462781577 0.400380818 0.862755151 1 10.28697014 -7.417824568 0.448793665 1.003661761 0.46766372 0.673489968 0.114149825 0.298513635 0.155019722 0.051513957 0.052464662 3.82E-08 7.417824568 -0.53599804 QALDSEEEEEDVAAKET(ph)LLR ddPTM_HeLa_Curcumin_4h_R1 1 QALDSEEEEEDVAAKETLLR 20 1 Q8NC44;H7C3D5 Q8NC44 FAM134A Protein FAM134A 1 0 QALDS(0.324)EEEEEDVAAKET(0.676)LLR 86.016 0.0014791 4453700 1545.9 1266 1357.1 2068.1 1354.3 1043.5 665.55 888.87 2349.8 1810.9 TRUE FALSE FALSE 1423.540384 1375.427399 1407.39532 2059.54275 1338.150857 827.0663373 684.2235418 1159.882371 2092.032819 1873.82864 0.759696139 0.73401984 0.751080056 1.099109441 0.71412659 0.441377786 0.365147339 0.61899063 1.11644831 1 10.87177331 -4.08838356 0.243545245 0.960161882 9.64E-21 0.523697828 0.166183775 7.847595957 0.351116028 0.126474036 2.310074074 8.16E-05 4.08838356 -0.960161882 GSISLNSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 GSISLNSSPR 10 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 0 GSISLNS(0.227)S(0.772)PR 98.754 0.013403 17859000 3609 2798 2770.8 3402.4 3124.4 4121.4 2535 1090.1 3525.6 3186 TRUE FALSE FALSE 3323.343842 3039.846652 2873.488285 3388.32177 3087.143571 3266.575182 2606.125277 1422.466472 3138.850501 3296.713263 1.008077918 0.92208403 0.871622145 1.02778783 0.936430719 0.990858143 0.790522278 0.431480192 0.952115107 1 11.6868127 -4.289343005 1.857632873 0.986118855 0.271870797 0.913901208 0.049328887 0.150028386 0.547912965 0.007233234 0.181740647 5.14E-05 4.289343005 -0.714248058 down QALYLMFDTSQES(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 1 QALYLMFDTSQESPVK 16 0 H0Y911;Q4VXL4;D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-2;O95359-6;O95359-1;O95359-5;O95359-3;O95359;E9PGB3 H0Y911 TACC2 Transforming acidic coiled-coil-containing protein 2 1 0 QALYLMFDTS(0.001)QES(0.999)PVK 124.04 0.00068889 11255000 2079.8 1690.5 2056.8 1968 2369.6 2353.7 2517.6 1251.2 2059.5 1774.4 TRUE FALSE FALSE 1915.181635 1836.619287 2133.026817 1959.856937 2341.344068 1865.516088 2588.23708 1632.68512 1833.578003 1836.060268 1.043093012 1.000304467 1.161741177 1.067425167 1.275200008 1.016042949 1.409668912 0.889232858 0.998648048 1 10.8423977 -6.760341596 24.9918393 1.019414686 1.146648658 0.173448389 0.133140546 34.31846934 781275.6221 0.018407607 0.025194276 1.74E-07 6.760341596 0.127233971 QAPAPTVIRDPPSITPAVKS(ph)PLPGPSEEK ddPTM_HeLa_Curcumin_4h_R1 2 QAPAPTVIRDPPSITPAVKSPLPGPSEEK 29 2 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 0 QAPAPT(0.001)VIRDPPS(0.043)IT(0.113)PAVKS(0.838)PLPGPS(0.005)EEK;QAPAPT(0.019)VIRDPPS(0.213)IT(0.213)PAVKS(0.549)PLPGPS(0.005)EEK ; 59.561 0.00069914 102270000 4084.3 3131.5 3352.3 3889.3 3397.4 4588.5 3479.9 2555 4285.1 3558.2 TRUE FALSE FALSE 3761.023345 3402.172906 3476.539187 3873.207107 3356.888224 3636.793377 3577.536628 3334.007738 3815.035251 3681.847185 1.021504467 0.924039683 0.944237773 1.05197389 0.911740237 0.98776326 0.971668961 0.905525833 1.036174251 1 11.84621403 -1 0.206553005 1.013808235 0.592510249 0.25579291 0.043132438 52.7506676 0.614314198 0.03689717 7.324318825 0.1 1 -0.421297986 QAPGVGAVGGGS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 QAPGVGAVGGGSPER 15 0 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74;H7BZQ3 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 0 QAPGVGAVGGGS(1)PER 97.291 0.0048902 13200000 1426.3 2537.5 1509.7 1744.9 1906.7 1794.8 1325 1504.8 1984.9 1798 TRUE FALSE FALSE 1313.40685 2756.830193 1565.65081 1737.680066 1883.963848 1422.538248 1362.175934 1963.606593 1767.161436 1860.480366 0.705950395 1.481784083 0.841530413 0.93399538 1.012622268 0.764608041 0.732163563 1.055429892 0.949841486 1 10.86145945 -3.941540006 17.23468103 0.900473257 2.632205311 0.003571625 0.2126187 63107969.51 362942104.4 0.029826016 3871825230 0.000114409 3.941540006 1.731732055 QAPGVGAVGGGS(ph)PEREEVGAGYNS(ph)EDEYEAAAAR ddPTM_HeLa_Curcumin_4h_R1 3 QAPGVGAVGGGSPEREEVGAGYNSEDEYEAAAAR 34 1 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74;H7BZQ3 A0A087WXV6 OTUD5 OTU domain-containing protein 5 2 0 QAPGVGAVGGGS(0.677)PEREEVGAGY(0.633)NS(0.675)EDEY(0.015)EAAAAR;QAPGVGAVGGGS(0.996)PEREEVGAGY(0.439)NS(0.491)EDEY(0.075)EAAAAR;QAPGVGAVGGGS(0.942)PEREEVGAGY(0.482)NS(0.535)EDEY(0.04)EAAAAR ;; 63.111 0.00023409 224859500 4691.21 4145.9 4327.28 5196.6 4640.5 5805.8 3717.85 3588.6 5727 4075.6 TRUE FALSE FALSE 4319.895778 4504.253122 4487.652803 5175.097846 4585.165068 4601.611635 3822.162865 4682.74762 5098.762428 4217.226797 1.024345141 1.068060443 1.064124132 1.227132923 1.087246499 1.091146352 0.906321393 1.110385532 1.209032066 1 12.04207889 -7.312562908 1.985302889 1.009362816 1.079969204 0 0.096509155 0.463945333 3.46051444 0.013829748 0.01608956 4.87E-08 7.312562908 0.070606389 QAPGVGAVGGGSPEREEVGAGYNS(ph)EDEYEAAAAR ddPTM_HeLa_Curcumin_4h_R1 1 QAPGVGAVGGGSPEREEVGAGYNSEDEYEAAAAR 34 1 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74;H7BZQ3 A0A087WXV6 OTUD5 OTU domain-containing protein 5 1 0 QAPGVGAVGGGSPEREEVGAGY(0.144)NS(0.855)EDEY(0.002)EAAAAR 119.91 2.48E-18 9763000 808.87 653.15 729.58 770.78 607.12 913.76 865.66 511.73 1126.9 749.92 TRUE FALSE FALSE 744.847086 709.6053756 756.6188766 767.5907166 599.8804905 724.2358758 889.9480898 667.7541213 1003.281889 775.9796642 0.959879647 0.914463881 0.975049878 0.989189217 0.773062128 0.933318113 1.146870377 0.860530439 1.292922915 1 9.599875034 -8.48914556 0.783197126 0.996991063 0.945822506 0.105665679 0.130370358 1.570550733 1.996745525 0.039663064 0.019830253 3.24E-09 8.48914556 -0.051168557 QAPLPS(ph)PESLDLGR ddPTM_HeLa_Curcumin_4h_R1 1 QAPLPSPESLDLGR 14 0 H3BRS1;Q12968 H3BRS1 NFATC3 "Nuclear factor of activated T-cells, cytoplasmic 3" 1 0 QAPLPS(0.617)PES(0.383)LDLGR 101.3 0.0055388 0 809.74 468.78 777.39 675.48 1095.6 1796.2 1462.3 821.08 968.52 616.47 TRUE FALSE FALSE 745.6482246 509.2992544 806.2007573 672.6850427 1082.535686 1423.647873 1503.328202 1071.423512 862.2757791 637.8922866 1.168924974 0.798409489 1.263850926 1.054543309 1.69705091 2.231799792 2.35671168 1.679630769 1.351757651 1 9.317169023 -5.596581222 2.923372958 1.069953055 2.11063662 0.805267606 0.218550102 0.066376085 1.144272911 0.02792941 0.061714749 2.53E-06 5.596581222 1.040683565 QAPPHIELSNS(ph)SPDPMAEAER ddPTM_HeLa_Curcumin_4h_R1 1 QAPPHIELSNSSPDPMAEAER 21 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 QAPPHIELS(0.003)NS(0.731)S(0.266)PDPMAEAER 81.799 0.00064507 27963000 1736.5 1367.8 1460.4 1470.1 1559.5 1681 949.91 830.09 1622.5 1608.2 TRUE FALSE FALSE 1599.054193 1486.026537 1514.523709 1464.017116 1540.903981 1332.341651 976.561918 1083.18062 1444.515809 1664.08483 0.96092108 0.892999269 0.9101241 0.879773128 0.925976821 0.800645272 0.586846235 0.650916708 0.86805419 1 10.70051326 -3.919972942 0.417035381 0.986819221 0.163290195 0.750412214 0.062899604 1.578778791 0.151491471 0.012632866 0.684612394 0.000120234 3.919972942 -0.823529026 QAPPHIELSNSS(ph)PDPMAEAER ddPTM_HeLa_Curcumin_4h_R1 3 QAPPHIELSNSSPDPMAEAER 21 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 QAPPHIELSNS(0.064)S(0.936)PDPMAEAER;QAPPHIELSNS(0.089)S(0.911)PDPMAEAER;QAPPHIELSNS(0.221)S(0.779)PDPMAEAER ;; 197.07 1.48E-13 112544000 7381.9 6367.1 6159.9 5774.7 5887.2 5824.26 3768.2 3834.96 8173.5 5635 TRUE FALSE FALSE 6797.614826 6917.443753 6388.191313 5750.805821 5816.998985 4616.242823 3873.92555 5004.22165 7276.887499 5830.815831 1.165808529 1.1863595 1.095591337 0.986278076 0.997630375 0.791697587 0.664388254 0.85823696 1.248005032 1 12.50948204 -5.419710213 1.665577056 1.08783904 0.747534936 0.750238417 0.087875463 0.147361262 0.78778933 0.01310166 0.039670593 3.80E-06 5.419710213 -0.340304104 QAQAQES(ph)EEEEESR ddPTM_HeLa_Curcumin_4h_R1 4 QAQAQESEEEEESR 14 0 H0YLQ7;Q9NVM6 H0YLQ7 DNAJC17 DnaJ homolog subfamily C member 17 1 0 QAQAQES(1)EEEEESR;QAQAQES(0.999)EEEEES(0.001)R;QAQAQES(1)EEEEESR;QAQAQES(1)EEEEESR ;;; 244 8.45E-29 178990000 8909 7929.7 7608.8 7335.1 7947.9 9597 8312.9 6846.6 8531.6 7708.3 TRUE FALSE FALSE 8203.843249 8615.107934 7890.788821 7304.7493 7853.126483 7606.47402 8546.137601 8934.096822 7595.704825 7976.162851 1.028545104 1.080106825 0.989296353 0.915822487 0.984574492 0.953650792 1.071459768 1.1200996 0.95230062 1 12.96147915 -4.561863735 5.866174317 1.004582339 1.109260396 0.46195101 0.045041453 0.112863767 9.988386021 0.006234149 0.025105386 2.74E-05 4.561863735 0.104678056 QAQEYEALLNIK ddPTM_HeLa_Curcumin_4h_R1 1 QAQEYEALLNIK 12 0 P05783;F8VZY9;CON__P05784 P05783 KRT18 "Keratin, type I cytoskeletal 18" 0 0 240.85 7.88E-50 1849900 656.59 517.51 729.46 794.21 654.5 605.7 632.5 512.08 646.4 685.25 FALSE FALSE TRUE 604.6202087 562.2412584 756.4944293 790.9237695 646.695515 480.0709924 650.2462477 668.2108347 575.4915372 709.0623865 0.852703824 0.792936234 1.066894033 1.115450184 0.912043182 0.677050428 0.917050827 0.94238652 0.811623276 1 9.469768758 -5.5089589 24.80346144 0.943236675 0.842967313 0.113188477 0.117974648 970.6698396 1729612.794 0.017305333 0.037270222 3.10E-06 5.5089589 -0.100269362 QAQIEVVPS(ph)ASALIIK ddPTM_HeLa_Curcumin_4h_R1 1 QAQIEVVPSASALIIK 16 0 P30050 P30050 RPL12 60S ribosomal protein L12 1 0 QAQIEVVPS(0.819)AS(0.181)ALIIK 165.75 0.00020107 8434800 1973.9 1862.1 1784.2 2433.1 1984.7 2574.5 1813.8 1680.4 2225.7 1933.4 TRUE FALSE FALSE 1817.663732 2023.051627 1850.324022 2423.032477 1961.033749 2040.519679 1864.690346 2192.746224 1981.546278 2000.585506 0.908565881 1.011229773 0.924891246 1.211161667 0.980229909 1.019961243 0.932072306 1.09605224 0.990483172 1 10.96620658 QAQIEVVPSASALIIK ddPTM_HeLa_Curcumin_4h_R1 1 QAQIEVVPSASALIIK 16 0 P30050 P30050 RPL12 60S ribosomal protein L12 0 0 188.4 3.79E-08 481960 546.16 443.35 269.79 285.41 331.98 609.47 370.54 346.81 379.08 266.02 FALSE FALSE TRUE 502.9308597 481.6711985 279.7886547 284.229049 328.0213553 483.0590519 380.9363551 452.5507725 337.4958724 275.2641752 1.827084325 1.749850659 1.016436863 1.032568255 1.191660175 1.754892556 1.38389369 1.644059828 1.2260799 1 8.10467305 -9.640756692 1.492851068 1.001881958 1.490777298 0.15198454 0.291693103 0.472369943 1.90394086 0.225479171 0.052025666 2.29E-10 9.640756692 0.48889534 QAQQERDELADEIANS(ph)SGKGALALEEK ddPTM_HeLa_Curcumin_4h_R1 1 QAQQERDELADEIANSSGKGALALEEK 27 2 P35579;P35579-2 P35579 MYH9 Myosin-9 1 0 QAQQERDELADEIANS(0.5)S(0.5)GKGALALEEK 73.461 8.18E-05 6345000 1218.3 881.53 1276.7 1203.1 1050.3 1483 1164.9 1123.5 1210.4 1142.6 TRUE FALSE FALSE 1121.870269 957.7255252 1324.015625 1198.121891 1037.775858 1175.409083 1197.583959 1466.049978 1077.622148 1182.305265 0.948883764 0.810049277 1.119859367 1.013377785 0.877756269 0.994167173 1.012922799 1.239992768 0.91145847 1 10.20738686 -4.211539023 2.400116286 0.970550271 1.324522671 0.520900521 0.07991744 0.406975607 2.509974353 0.010490618 0.312149104 6.14E-05 4.211539023 0.3539724 QAQQERDELADEIANSS(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 QAQQERDELADEIANSSGK 19 1 P35579;P35579-2 P35579 MYH9 Myosin-9 1 0 QAQQERDELADEIANS(0.052)S(0.948)GK 123.58 8.07E-05 15699000 958.54 1063.6 1164.6 1275.8 1233.3 1372 885.29 1038.3 1252.8 1101.2 TRUE FALSE FALSE 882.6705476 1155.532845 1207.7611 1270.521078 1218.593703 1087.431734 910.1288548 1354.87289 1115.370974 1139.466618 0.774634845 1.014099778 1.059935483 1.115013865 1.069442214 0.954333999 0.798732355 1.189041319 0.978853576 1 10.15414294 -7.082329871 13.30810007 0.893590828 1.023792794 0.158464477 0.112800029 1.764551298 283.1561826 0.020849187 0.025537189 8.27E-08 7.082329871 0.130201966 QAQQERDELADEIANSSGK ddPTM_HeLa_Curcumin_4h_R1 2 QAQQERDELADEIANSSGK 19 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ; ; 163.45 1.02E-05 24296600 5392.8 4423.8 5074.1 5463.8 5149.5 5894.2 4358.4 4684.8 5729.5 4587.3 FALSE FALSE TRUE 4965.95419 4806.17356 5262.15061 5441.192243 5088.095576 4671.676479 4480.684974 6113.173954 5100.988185 4746.708334 1.04618903 1.012527676 1.108589414 1.146308528 1.071920838 0.984192866 0.943956245 1.287876466 1.074636954 1 12.21271169 -5.601555917 0.011369477 1.69E-06 2.142049773 0.043998055 0.09107854 4146.251388 12.69060091 1140.616151 1251.237715 2.50E-06 5.601555917 2.142048081 QAQTQT(ph)SPEHLVLQQK ddPTM_HeLa_Curcumin_4h_R1 1 QAQTQTSPEHLVLQQK 16 0 H0Y5D5;A0A494C0L7;Q9BTG3;Q5SYW2;F5H2X7;Q9ULV3-5;Q9ULV3-3;Q9ULV3-4;Q9ULV3-2;Q9ULV3 H0Y5D5 CIZ1 Cip1-interacting zinc finger protein 1 0 QAQT(0.047)QT(0.477)S(0.477)PEHLVLQQK 94.973 0.0022201 0 2985.1 2335.8 2530.2 2746.7 2657.6 3529.5 2536.8 1740 2723.7 2500.9 TRUE FALSE FALSE 2748.826185 2537.696144 2623.971438 2735.334883 2625.909856 2797.441914 2607.975781 2270.51799 2424.916924 2587.806089 1.062222628 0.980636128 1.013975293 1.057009215 1.014724352 1.081009094 1.007794128 0.877391084 0.937055112 1 11.3375138 -4.279352159 4.058158995 1.029483842 0.866628177 0.497282766 0.040992333 0.093872322 3.249523349 0.004366731 0.043228945 5.26E-05 4.279352159 -0.162855664 QAREES(ph)EESEAEPVQR ddPTM_HeLa_Curcumin_4h_R1 2 QAREESEESEAEPVQR 16 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 0 QAREES(0.994)EES(0.006)EAEPVQR;QAREES(1)EESEAEPVQR ; 88.471 0.0029796 13105800 3400.9 2686.36 2718.28 3117.6 2641.16 3054.7 2556.94 1936.11 3841 2826.5 TRUE FALSE FALSE 3131.715176 2918.556988 2819.021848 3104.700197 2609.665892 2421.120786 2628.680855 2526.421026 3419.65191 2924.720665 1.070774113 0.997892559 0.963860201 1.061537341 0.892278679 0.827812658 0.898780142 0.863816178 1.169223424 1 11.51408313 -5.683187242 5.493519488 1.027124418 0.866558545 0.690443658 0.056283312 0.067754136 3.506214728 0.005685613 0.011453606 2.07E-06 5.683187242 -0.160565873 QAS(ph)GDTPTTPK ddPTM_HeLa_Curcumin_4h_R1 1 QASGDTPTTPK 11 0 A0A087WWW8;Q9Y6J0-2;Q9Y6J0;B5MEB3 A0A087WWW8 CABIN1 Calcineurin-binding protein cabin-1 1 0 QAS(0.447)GDT(0.057)PT(0.439)T(0.057)PK 93.839 0.01485 6251300 3595.5 3503.9 3305.3 3462.1 4308.2 4170.3 6452.5 6283.1 3363.4 3862.4 TRUE FALSE FALSE 3310.912381 3806.761503 3427.797326 3447.774748 4256.827529 3305.332771 6633.539784 8198.788266 2994.443435 3996.618113 0.828428508 0.952495684 0.857674471 0.862673053 1.065107401 0.827032425 1.65978825 2.051431494 0.749244324 1 11.96456401 -4.623890984 3.358822805 0.916057491 1.994788971 0.940522054 0.098636594 0.034810191 0.737740527 0.012794476 0.061865487 2.38E-05 4.623890984 1.07873148 QAS(ph)LDGLQQLR ddPTM_HeLa_Curcumin_4h_R1 3 QASLDGLQQLR 11 0 Q3MII6 Q3MII6 TBC1D25 TBC1 domain family member 25 1 0 QAS(1)LDGLQQLR;QAS(1)LDGLQQLR;QAS(1)LDGLQQLR ;; 144.8 0.001023 59910500 3229 2332.04 2514.6 2795.8 3048.07 4229.72 2964.07 2474.22 3054.52 2326.51 TRUE FALSE FALSE 2973.421243 2533.611146 2607.793288 2784.23172 3011.723756 3352.428393 3047.233827 3228.598288 2719.446798 2407.356049 1.235139789 1.052445544 1.083260322 1.156551695 1.251050403 1.392576887 1.265801055 1.341138669 1.129640461 1 11.23323382 -1 0.047273869 0.554811601 2.381703553 0.54042033 0.082071178 286.8581153 1.036990029 9.972673699 39.31335991 0.1 1 1.826891953 QAS(ph)PTEVVER ddPTM_HeLa_Curcumin_4h_R1 2 QASPTEVVER 10 0 C9JW01;A0A0A0MR59;Q8TB72-2;Q8TB72-4;Q8TB72-3;Q8TB72;A0A0C4DG68 C9JW01 PUM2 Pumilio homolog 2 1 0 QAS(0.5)PT(0.5)EVVER;QAS(0.886)PT(0.114)EVVER ; 112.02 0.0067355 100478000 5310.4 4632.8 4526.8 4645.9 4555.5 5676.1 4567.9 4253.4 4851.1 4120.8 TRUE FALSE FALSE 4890.076236 5033.238589 4694.56719 4626.676497 4501.178638 4498.812877 4696.06298 5550.24208 4318.946467 4263.997493 1.14682906 1.18040374 1.100977943 1.085056101 1.055624129 1.055069306 1.101328738 1.301652285 1.012886727 1 12.05799087 -9.292226916 0.984696691 0.998936717 1.123030659 0.329565168 0.068976616 0.5564132 0.95435619 0.048941484 0.012729477 5.10E-10 9.292226916 0.124093942 QAS(ph)TDAGTAGALTPQHVR ddPTM_HeLa_Curcumin_4h_R1 5 QASTDAGTAGALTPQHVR 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 0 QAS(0.762)T(0.238)DAGTAGALTPQHVR;QAS(0.694)T(0.259)DAGT(0.045)AGALT(0.001)PQHVR;QAS(0.5)T(0.5)DAGTAGALTPQHVR;QAS(0.535)T(0.444)DAGT(0.009)AGALT(0.013)PQHVR;QAS(0.628)T(0.372)DAGTAGALTPQHVR ;;;; 271.91 3.46E-54 382615000 11404 9157.9 9671.1 9550.8 9522.4 11983 9876.6 5684.98 11553.8 9474.4 TRUE FALSE FALSE 10501.36137 9949.468069 10029.51947 9511.28132 9408.851599 9497.590724 10153.71081 7418.304232 10286.37705 9803.634695 1.071170203 1.014875439 1.023040922 0.970179083 0.959730946 0.968782601 1.035708809 0.756689173 1.049241161 1 13.25910101 -4.25920888 24.98108151 1.018910436 0.756689081 0.818204325 0.035656594 71.76548126 803702.2508 0.005988181 0.053389185 5.51E-05 4.25920888 -0.262221354 QASASYDS(ph)EEEEEGLPMSYDEKR ddPTM_HeLa_Curcumin_4h_R1 4 QASASYDSEEEEEGLPMSYDEKR 23 1 Q15059 Q15059 BRD3 Bromodomain-containing protein 3 1 0 QAS(0.007)AS(0.023)Y(0.001)DS(0.97)EEEEEGLPMSYDEKR;QAS(0.059)AS(0.027)YDS(0.914)EEEEEGLPMSYDEKR;QAS(0.003)AS(0.028)YDS(0.968)EEEEEGLPMSYDEKR;QAS(0.002)AS(0.012)Y(0.002)DS(0.983)EEEEEGLPMSYDEKR ;;; 106.43 1.11E-05 304603000 9629.7 6416.3 7419.7 7914.9 7110.9 9625 7884.1 7759.1 9673.4 7457.8 TRUE FALSE FALSE 8867.499084 6970.896382 7694.680609 7882.150241 7026.107162 7628.666504 8105.306627 10124.81387 8612.252222 7716.957995 1.149092569 0.903321799 0.997113191 1.021406394 0.910476274 0.98855877 1.050324057 1.312021379 1.11601647 1 12.91381654 -4.263671289 5.141457691 1.034839715 1.324176252 0.570003112 0.075747891 0.109305201 9.517528834 0.012218551 0.111505483 5.45E-05 4.263671289 0.289336536 QASEGPLK ddPTM_HeLa_Curcumin_4h_R1 1 QASEGPLK 8 0 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 115.49 0.0034503 21538000 5929.6 3734.3 5856.3 2928.6 5334 7668.8 6125.3 5186.9 4340 5098.2 FALSE FALSE TRUE 5460.265903 4057.076252 6073.33963 2916.482229 5270.395534 6078.204435 6297.159433 6768.361932 3863.912858 5275.362071 1.035050453 0.769061194 1.151264984 0.552849679 0.999058541 1.152187159 1.193692366 1.283013723 0.732445054 1 12.3650544 -5.130790606 3.047549469 0.971595554 1.229211828 0.354052301 0.177548833 0.237029764 4.164863515 0.022494051 0.066290858 7.40E-06 5.130790606 0.257616275 QAST(ph)DAGTAGALT(ph)PQHVR ddPTM_HeLa_Curcumin_4h_R1 2 QASTDAGTAGALTPQHVR 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 2 0 QAS(0.144)T(0.856)DAGT(0.001)AGALT(1)PQHVR;QAS(0.36)T(0.639)DAGT(0.001)AGALT(1)PQHVR ; 105.63 0.0014771 23184800 3632.1 3104.5 3332.5 3810.3 3761.3 4712 4217.8 3190.3 3407.4 3203 TRUE FALSE FALSE 3344.615452 3372.839147 3456.005382 3794.533988 3716.448954 3734.678085 4336.140116 4163.007784 3033.616745 3314.304012 1.009145643 1.017661366 1.042754488 1.144896176 1.121336166 1.126836305 1.308310916 1.256073 0.915310344 1 11.69449023 -5.02501717 0.507830453 0.998698953 1.374417129 0.848163573 0.044943436 0.477236293 0.132241875 0.007696519 0.092647556 9.44E-06 5.02501717 0.375718175 QASTDAGTAGALT(ph)PQHVR ddPTM_HeLa_Curcumin_4h_R1 3 QASTDAGTAGALTPQHVR 18 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 0 QASTDAGTAGALT(1)PQHVR;QASTDAGTAGALT(1)PQHVR;QASTDAGT(0.027)AGALT(0.973)PQHVR ;; 201.48 1.24E-33 90099000 7735.2 6530.1 7242.7 7892.5 7432.5 9801.1 7131.9 3849.73 7783.4 6546.3 TRUE FALSE FALSE 7122.950758 7094.532746 7511.120833 7859.842926 7343.872292 7768.241379 7332.001919 5023.494955 6929.580493 6773.783438 1.051546868 1.047351574 1.108851634 1.160332774 1.084161069 1.146809822 1.08240867 0.741608438 1.023000005 1 12.72574615 -4.258513817 24.9106081 1.056084954 0.741608318 0.778884733 0.052631877 116.7384504 993950.2531 0.008909999 0.083427087 5.51E-05 4.258513817 -0.314476636 QATENAKEEVR ddPTM_HeLa_Curcumin_4h_R1 2 QATENAKEEVR 11 1 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 0 ; ; 114.89 0.0014329 4132400 5331.7 4816.8 5311.6 5318.5 6224.3 5647.4 5195.3 5019.3 5654.8 5931.1 FALSE FALSE TRUE 4909.690319 5233.142729 5508.452569 5296.493456 6150.079288 4476.065581 5341.066136 6549.661464 5034.482588 6137.205284 0.799987957 0.852691492 0.897550646 0.863013898 1.002097698 0.729332876 0.870276598 1.067205863 0.820321686 1 12.58336613 -9.567033744 1.364347894 0.99954213 0.871349841 0 0.105772303 0.525385913 1.762966523 0.061119867 0.014577754 2.71E-10 9.567033744 -0.128192289 QATENAKEEVRR ddPTM_HeLa_Curcumin_4h_R1 2 QATENAKEEVRR 12 2 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 0 0 ; ; 74.698 0.011952 32954100 7640.6 6323.4 5394.6 7081.5 5632.9 7297.7 5953.7 6993.4 7801.4 6719.9 FALSE FALSE TRUE 7035.838448 6869.966519 5594.528622 7052.198629 5565.731346 5784.074758 6120.744798 9125.655466 6945.605938 6953.416025 1.011853515 0.987998776 0.804572688 1.014206342 0.800431231 0.831832115 0.880250049 1.312398889 0.998876799 1 12.76350619 -6.978123185 24.98247382 1.005299025 0.927098546 0.036178051 0.140884377 517.2026817 590623.6946 0.021517676 0.028278674 1.05E-07 6.978123185 -0.078200479 QATPGVPAQQS(ph)PSM ddPTM_HeLa_Curcumin_4h_R1 1 QATPGVPAQQSPSM 14 0 R4GMQ1;O60341;O60341-2 R4GMQ1 KDM1A Lysine-specific histone demethylase 1A 1 0 QATPGVPAQQS(0.999)PS(0.001)M 103.14 0.0040147 8010600 2254.7 1735.8 1917 2344.1 2590.9 2984.2 1983.5 2553.2 2356.9 2023.5 TRUE FALSE FALSE 2076.238116 1885.834817 1988.045706 2334.400735 2560.00521 2365.243281 2039.151672 3331.658927 2098.353967 2093.816474 0.991604633 0.900668631 0.949484222 1.114902268 1.222650237 1.129632568 0.973892266 1.591189566 1.002167092 1 11.03191928 -6.047796844 3.455810955 0.984389373 1.202893242 0.402640302 0.147759514 0.203906992 4.926096618 0.020621702 0.036628271 8.96E-07 6.047796844 0.218503869 QATVMRQNVK ddPTM_HeLa_Curcumin_4h_R1 1 QATVMRQNVK 10 1 Q9P2D3-2;Q9P2D3-3;Q9P2D3 Q9P2D3-2 HEATR5B HEAT repeat-containing protein 5B 0 0 133.86 0.0047245 2111300 864.05 524.83 412.48 527.88 671.94 693.31 339.52 351.53 661.79 613.54 FALSE FALSE TRUE 795.6595308 570.1939666 427.7668717 525.6957724 663.9275544 549.5096908 349.0460174 458.7098788 589.1932927 634.8604693 1.253282523 0.898140606 0.673796672 0.828049308 1.045784998 0.865559784 0.549799577 0.722536527 0.92806738 1 9.310295739 -7.060662109 5.503688549 1.118742429 0.787857844 0.402050812 0.147327233 0.135073801 8.438351505 0.026348307 0.032664144 8.70E-08 7.060662109 -0.330884586 QATVSWDSGGSDEAPPKPS(ph)RPGYPSPR ddPTM_HeLa_Curcumin_4h_R1 1 QATVSWDSGGSDEAPPKPSRPGYPSPR 27 2 Q05397-5;Q05397;Q05397-7;Q05397-2;E7ESA6;H0YBP1;H0YB16;H0YBZ1;E9PEI4;Q05397-6;B4DWJ1;E5RHK7;E5RG80;E5RJQ2 Q05397-5 PTK2 Focal adhesion kinase 1 1 0 QATVSWDS(0.005)GGS(0.002)DEAPPKPS(0.686)RPGY(0.143)PS(0.165)PR 53.777 0.0048585 13033000 1733.2 1699.8 1343.1 1483.9 1485.5 1975.9 1361.8 959.51 1966.9 1863.7 TRUE FALSE FALSE 1596.015391 1846.723138 1392.876468 1477.760015 1467.786383 1566.076067 1400.008443 1252.060182 1751.135991 1928.463436 0.827609879 0.957613768 0.722272687 0.766288843 0.76111704 0.812084916 0.725970955 0.649252746 0.908047287 1 10.91323608 -13.52287875 0.03869355 2.22028953 0.04977185 0.650344867 0.062752813 251.7359907 0.778214198 37.3057477 12.56814664 3.00E-14 13.52287875 -2.17051768 QAVEMKNDKS(ph)EEEQSSSSVK ddPTM_HeLa_Curcumin_4h_R1 2 QAVEMKNDKSEEEQSSSSVK 20 2 P07910;P07910-2;P07910-4;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 1 0 QAVEMKNDKS(0.812)EEEQS(0.134)S(0.039)S(0.012)S(0.003)VK;QAVEMKNDKS(0.881)EEEQS(0.082)S(0.026)S(0.008)S(0.003)VK ; 67.396 0.0054924 42065000 3320.7 2206.5 2583.7 2814.8 2004.78 3177.7 2247 2590.1 3224.6 3027.9 TRUE FALSE FALSE 3057.863091 2397.220028 2679.454195 2803.153103 1980.874308 2518.6092 2310.044773 3379.809567 2870.869448 3133.1193 0.97598042 0.765122486 0.855203374 0.894684446 0.632237115 0.803866358 0.737298696 1.078736315 0.916297521 1 11.61338399 -7.307443023 7.854457846 0.988886224 0.816384407 0.238120879 0.111788255 0.232190013 36.23399697 0.017613592 0.02015929 4.93E-08 7.307443023 -0.172501818 QAVMENMRRK ddPTM_HeLa_Curcumin_4h_R1 1 QAVMENMRRK 10 2 Q9GZT5 Q9GZT5 WNT10A Protein Wnt-10a 0 0 63.076 0.010658 9964700 4016.1 4337.7 3553.7 3478.5 5148.2 9830.9 4447.1 2973.9 4968.4 3665.2 FALSE FALSE TRUE 3698.221447 4712.63146 3685.403248 3464.106889 5086.811077 7791.860523 4571.873657 3880.62842 4423.37895 3792.565427 0.975123968 1.242597274 0.971744145 0.913394101 1.341258622 2.05450919 1.205483134 1.023219901 1.166328976 1 11.88895835 -5.658800408 5.490929872 1.003654787 1.449514304 0.301909999 0.265275463 0.161651463 7.355731376 0.037131729 0.074995807 2.19E-06 5.658800408 0.445859516 QAY(ph)T(ph)PFKT(ph)S(ph)PDK ddPTM_HeLa_Curcumin_4h_R1 1 QAYTPFKTSPDK 12 1 Q00532-2 Q00532-2 4 0 QAY(1)T(1)PFKT(1)S(1)PDK 49.333 0.0094666 0 191.87 219.43 326.7 253.68 368.37 345.57 177.77 279.35 269.26 445.09 TRUE FALSE FALSE 176.683287 238.3965514 338.8077894 252.6303394 363.9774283 273.8948866 182.7577478 364.522529 239.7228517 460.5568444 0.383629707 0.517626769 0.735648148 0.548532374 0.790298598 0.594703759 0.39681909 0.791482167 0.520506545 1 8.847235422 -9.494908421 1.241867443 0.999881981 0.572256185 0 0.200853968 0.279461183 0.77164136 0.101050201 0.02460183 3.20E-10 9.494908421 -0.427625796 QCEGITS(ph)PEGSK ddPTM_HeLa_Curcumin_4h_R1 2 QCEGITSPEGSK 12 0 Q9Y570-4;Q9Y570;Q9Y570-2 Q9Y570-4 PPME1 Protein phosphatase methylesterase 1 1 0 QCEGIT(0.293)S(0.705)PEGS(0.002)K;QCEGIT(0.254)S(0.745)PEGS(0.001)K ; 183.28 6.49E-05 167057000 11574.2 9987.6 9597.1 10379.4 10262.7 13466.1 11028.6 47934 10719.7 9513.9 TRUE FALSE FALSE 10658.08986 10850.88364 9952.776968 10336.45279 10140.32401 10673.07907 11338.03283 62548.85594 9543.775729 9844.507317 1.082643297 1.10222719 1.010997976 1.049971569 1.030048907 1.084165893 1.151711555 6.35368068 0.96945184 1 13.26510329 -4.261322019 6.458069437 1.047148301 6.462657277 0.999385992 0.039420831 0.002048933 0.502846501 0.00576137 0.04825874 5.48E-05 4.261322019 5.415508976 QCQKT(ph)S(ph)LS(ph)VTR ddPTM_HeLa_Curcumin_4h_R1 1 QCQKTSLSVTR 11 1 Q15973-2;Q15973-1;Q15973 Q15973-2 ZNF124 Zinc finger protein 124 3 0 QCQKT(0.999)S(0.994)LS(0.949)VT(0.057)R 74.78 0.0085172 0 2572.7 2237.2 2295.3 2818 2348.5 2699.8 2120.5 2293.2 2690.7 2929.9 TRUE FALSE FALSE 2369.06808 2430.573599 2380.365837 2806.339863 2320.495671 2139.831047 2179.995523 2992.386123 2395.536942 3031.713807 0.781428667 0.801716044 0.785155192 0.925661207 0.765407231 0.705815649 0.719063758 0.987027904 0.790159327 1 11.56591785 -9.265301875 0.783829259 1.01300934 0.801914572 0 0.104590622 0.551483851 0.549536417 0.074257054 0.016040064 5.43E-10 9.265301875 -0.211094767 QDDGSSSAS(ph)PSVQGAPR ddPTM_HeLa_Curcumin_4h_R1 2 QDDGSSSASPSVQGAPR 17 0 Q9NQA3 Q9NQA3 WASH6P WAS protein family homolog 6 1 0 QDDGS(0.002)S(0.011)S(0.373)AS(0.559)PS(0.055)VQGAPR;QDDGS(0.004)S(0.004)S(0.009)AS(0.777)PS(0.206)VQGAPR ; 167.97 8.63E-05 39187000 3671 3647.5 3052.7 3564.7 3248.3 3721.9 3007.2 2019.56 3575.9 3425.2 TRUE FALSE FALSE 3380.436476 3962.773647 3165.835747 3549.950216 3209.566144 2949.935986 3091.573939 2635.314547 3183.632716 3544.225445 0.953787091 1.118092996 0.893237689 1.001615239 0.905576181 0.832321767 0.872284787 0.743551613 0.898259088 1 11.79125466 -5.000559164 0.806819088 0.986704929 0.74740242 0.560391428 0.064930755 0.52772809 0.446021586 0.00931162 0.089985494 9.99E-06 5.000559164 -0.239302509 QDDS(ph)PPRPIIGPALPPGFIK ddPTM_HeLa_Curcumin_4h_R1 2 QDDSPPRPIIGPALPPGFIK 20 1 A0A0A0MRI1;Q8IXQ4-4;Q8IXQ4 A0A0A0MRI1 GPALPP1 GPALPP motifs-containing protein 1 1 0 QDDS(1)PPRPIIGPALPPGFIK;QDDS(1)PPRPIIGPALPPGFIK ; 108.28 0.00012411 204383000 5945.7 4480.6 5299.6 5128.4 5214 6353.8 5999.5 5554.1 6089.4 5373 TRUE FALSE FALSE 5475.091571 4867.883099 5496.007838 5107.18004 5151.826455 5035.950258 6167.829823 7247.519522 5421.408055 5559.71135 0.984779825 0.875563998 0.988541939 0.918605251 0.926635599 0.905793474 1.109379505 1.303578381 0.975124015 1 12.44079427 -4.432601132 2.949304131 0.969529446 1.309381464 0.85584084 0.04515797 0.092797029 1.340309209 0.007057076 0.059857492 3.69E-05 4.432601132 0.339852018 QDDSPSGASYGQDYDLS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 QDDSPSGASYGQDYDLSPSR 20 0 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 0 QDDSPSGASYGQDYDLS(0.944)PS(0.056)R;QDDSPSGASYGQDYDLS(1)PSR ; 243.7 8.22E-34 32829000 5454.2 5402 5602.1 5040 6067.6 7264 3537.5 3035.7 5493.2 4427.6 TRUE FALSE FALSE 5022.494315 5868.924809 5809.718754 5019.145815 5995.247833 5757.364518 3636.752729 3961.270955 4890.609703 4581.45877 1.096265309 1.281016616 1.268093646 1.095534428 1.30858928 1.256666229 0.793797983 0.86463093 1.067478711 1 12.16159132 -4.747429572 24.98582973 1.112780539 0.829214286 0.552870184 0.113719094 176.7782523 315270.0639 0.019129625 0.070856007 1.79E-05 4.747429572 -0.283566253 QDEHGYISR ddPTM_HeLa_Curcumin_4h_R1 7 QDEHGYISR 9 0 P04792 P04792 HSPB1 Heat shock protein beta-1 0 0 ;;;;;; ;;;;;; 139.15 0.0015444 544977700 54521.4 47416.4 48091.5 49640.3 53719.2 62147.7 47664.2 41621.9 52897.1 45629.9 FALSE FALSE TRUE 50205.97366 51514.86233 49873.8133 49434.90159 53078.63363 49257.56647 49001.52917 54312.22571 47094.42047 47215.53563 1.063335891 1.091057459 1.056300911 1.047004994 1.124177306 1.04324913 1.037826396 1.150304132 0.997434845 1 15.52697402 -13.52287875 0.170130242 0.685655067 1.094172135 0.470228893 0.033911299 39.85571741 0.442383485 4.12041718 0.052530513 3.00E-14 13.52287875 0.408517068 QDENDDDDDWNPCK ddPTM_HeLa_Curcumin_4h_R1 3 QDENDDDDDWNPCK 14 0 Q14974;Q14974-2 Q14974 KPNB1 Importin subunit beta-1 0 0 ;; ;; 220.53 3.38E-13 261378000 15855.9 14561.1 15560.5 15758.4 16072.6 16072.3 12740.5 13018.8 14236.4 14536.4 FALSE FALSE TRUE 14600.88878 15819.6966 16137.18582 15693.19592 15880.94474 12738.72381 13097.96414 16988.17219 12674.70254 15041.53882 0.970704458 1.051733921 1.072841417 1.043323832 1.055805854 0.846902964 0.870786181 1.129417169 0.842646666 1 13.87666455 -4.213612204 22.674855 0.989457851 1.12941916 0.207978199 0.086345784 14880.06645 7054051.264 0.010346029 8.517041638 6.11E-05 4.213612204 0.139961308 QDGGTAPVAS(ph)ASPK ddPTM_HeLa_Curcumin_4h_R1 1 QDGGTAPVASASPK 14 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 0 QDGGT(0.001)APVAS(0.883)AS(0.115)PK 158.14 0.00033843 6873700 2688.1 1942.4 2036.3 2218 2322.5 2270 2141.2 2442.8 2612.5 2392.2 TRUE FALSE FALSE 2475.334049 2110.292401 2111.767069 2208.822504 2294.805704 1799.176412 2201.276309 3187.598475 2325.915286 2475.328772 1.000002132 0.852530147 0.853125893 0.892335002 0.927071075 0.726843413 0.889286439 1.287747515 0.939638933 1 11.27340444 -7.288150435 21.59957432 1.000001049 0.906749257 0.02976403 0.13708036 244.6281798 197814.5352 0.022333527 0.025547829 5.15E-08 7.288150435 -0.093251792 QDIMPEVDKQSGS(ph)PESR ddPTM_HeLa_Curcumin_4h_R1 1 QDIMPEVDKQSGSPESR 17 1 Q8NI08-2;Q8NI08;Q8NI08-7 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 0 QDIMPEVDKQS(0.09)GS(0.863)PES(0.047)R 122.97 0.00028038 0 2000.4 1511.5 1539.7 1483.4 2408.1 2047.8 1616.5 1469.1 1794.3 1356.6 TRUE FALSE FALSE 1842.066229 1642.147325 1596.762636 1477.262084 2379.38498 1623.063197 1661.854639 1917.021827 1597.469779 1403.741749 1.312254359 1.169835781 1.137504557 1.052374545 1.69503043 1.156240596 1.183874912 1.365651359 1.138008313 1 10.45506183 QDKPMDT(ph)S(ph)VLSEEGGEPFQKK ddPTM_HeLa_Curcumin_4h_R1 1 QDKPMDTSVLSEEGGEPFQKK 21 2 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 QDKPMDT(0.721)S(0.721)VLS(0.559)EEGGEPFQKK 54.171 0.0088985 10138000 1837.4 1732 1477 1800.9 1805.1 2309.8 1584.7 2015.4 1641 1968.3 TRUE FALSE FALSE 1691.967851 1881.706362 1531.738919 1793.448353 1783.575361 1830.721443 1629.162417 2629.886182 1460.986406 2036.698278 0.830740552 0.923900404 0.752069629 0.880566538 0.875718991 0.898867281 0.799903665 1.291249769 0.7173308 1 10.99201656 -4.252926393 24.84683731 0.894625538 1.291249987 0.670313535 0.087944898 457.4401952 1335098.131 0.011469328 0.176678207 5.59E-05 4.252926393 0.396624449 QDKPMDTSVLS(ph)EEGGEPFQK ddPTM_HeLa_Curcumin_4h_R1 1 QDKPMDTSVLSEEGGEPFQK 20 1 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 QDKPMDT(0.041)S(0.15)VLS(0.808)EEGGEPFQK 104.66 0.00082563 26158000 3739.7 2854.7 3055.7 3730.3 3539.3 3166.3 2416.3 3538.3 2743.6 2745.9 TRUE FALSE FALSE 3443.698799 3101.447548 3168.94693 3714.865007 3497.096159 2509.573688 2484.094875 4617.111382 2442.633944 2841.319821 1.212006749 1.091551724 1.115308072 1.307443456 1.230799903 0.883242242 0.874274996 1.624988271 0.859682858 1 11.47234552 -9.44563361 1.110199562 0.997679744 1.156475742 0.151503811 0.208087897 1.149707861 2.474452384 0.144804064 0.033970971 3.58E-10 9.44563361 0.158795998 QDKPMDTSVLS(ph)EEGGEPFQKK ddPTM_HeLa_Curcumin_4h_R1 1 QDKPMDTSVLSEEGGEPFQKK 21 2 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 QDKPMDT(0.001)S(0.001)VLS(0.999)EEGGEPFQKK 69.649 0.0023784 19857000 1038.8 995.31 1027.2 870.22 865.85 763.9 635.23 1019.4 1087.2 828.05 TRUE FALSE FALSE 956.5778839 1081.340161 1065.268936 866.6192602 855.5253043 605.4585291 653.0528442 1330.210367 967.93688 856.8246759 1.11642196 1.262032002 1.243275276 1.011431258 0.998483504 0.706630593 0.762177914 1.552488397 1.129679043 1 9.742856219 -6.012967931 22.19952895 1.089744674 0.971128876 0.05322199 0.227147996 346.7208977 593551.99 0.033348877 0.057147912 9.71E-07 6.012967931 -0.118615798 QDNDT(ph)GNEEQEEEEDDEEEMEEK ddPTM_HeLa_Curcumin_4h_R1 1 QDNDTGNEEQEEEEDDEEEMEEK 23 0 A0A3B3ISR7;E9PIF2;Q13206 A0A3B3ISR7 DDX10 Probable ATP-dependent RNA helicase DDX10 1 0 QDNDT(1)GNEEQEEEEDDEEEMEEK 95.713 0.0001359 0 1167.6 1091.1 1309 949.54 1366.8 1311.1 749.05 595.57 1028.9 772.92 TRUE FALSE FALSE 1075.183228 1185.409822 1357.512692 945.6110551 1350.501803 1039.163081 770.066327 777.1565513 916.0322442 799.7789125 1.344350559 1.48217189 1.697359946 1.18234057 1.688593912 1.299312928 0.962849001 0.971714232 1.145356835 1 9.643457432 -2.601689906 13.53734114 1.240061965 1.217285835 0 0.26497065 0 0 0.038537933 0 0.002502131 2.601689906 -0.02277613 QDPFQESGLHLS(ph)PTAAEAK ddPTM_HeLa_Curcumin_4h_R1 1 QDPFQESGLHLSPTAAEAK 19 0 H3BN50;H3BQS0;Q15599-3;Q15599 H3BN50 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 0 QDPFQES(0.117)GLHLS(0.842)PT(0.041)AAEAK 74.047 0.0076988 7612800 1878.1 1579.3 1955.5 1564.8 2065.2 2885.6 1805.4 1055.2 1892.1 1561.7 TRUE FALSE FALSE 1729.446403 1715.807655 2027.97255 1558.325272 2040.573839 2287.094033 1856.054665 1376.925622 1684.541364 1615.968959 1.07022254 1.061782558 1.254957615 0.964328717 1.262755592 1.415308147 1.148570741 0.852074302 1.042434234 1 10.65818377 -7.374705968 0.805563691 1.017378366 1.161725398 0.091161268 0.149915508 0.840262122 1.126788631 0.038281436 0.042533387 4.22E-08 7.374705968 0.144347031 QDPSVLHTEEMR ddPTM_HeLa_Curcumin_4h_R1 2 QDPSVLHTEEMR 12 0 P50502;Q3KNR6;Q8NFI4;F8WAQ7 P50502 ST13;ST13P5 Hsc70-interacting protein;Putative protein FAM10A5 0 0 ; ; 143.76 0.00076982 24201000 11270 9679.1 10031.7 8841.4 11673.6 14889.7 10639.2 9350.9 12790.2 10162.5 FALSE FALSE TRUE 10377.96761 10515.71827 10403.48363 8804.816629 11534.39994 11801.40838 10937.70732 12201.94636 11387.14706 10515.64612 0.98690727 1.000006862 0.989333752 0.837306289 1.096879813 1.122271351 1.040136497 1.160361068 1.082876595 1 13.36024988 -5.575690589 24.99999006 0.983355888 1.102300822 0.4757721 0.062826509 53.14489341 25157.43216 0.007466509 0.014933021 2.66E-06 5.575690589 0.118944934 QDPVVHLS(ph)PNK ddPTM_HeLa_Curcumin_4h_R1 2 QDPVVHLSPNK 11 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 QDPVVHLS(1)PNK;QDPVVHLS(1)PNK ; 110.44 0.0065524 31148000 11250.7 9026.6 10233.9 9097.3 11070.4 10678.3 9235.9 6458.47 9217 8779 TRUE FALSE FALSE 10360.19522 9806.819082 10613.17734 9059.657783 10938.39271 8463.500211 9495.034497 8427.627772 8205.91816 9084.069597 1.140479508 1.079562302 1.168328492 0.997312679 1.204129118 0.931685972 1.045240175 0.927737033 0.903330613 1 13.14912304 -5.225073413 24.97793536 1.079266039 0.975922968 0.209040403 0.089613901 593.0471268 407333.2444 0.01062134 0.027078451 5.96E-06 5.225073413 -0.103343071 QDRT(ph)LT(ph)IVDTGIGMTK ddPTM_HeLa_Curcumin_4h_R1 1 QDRTLTIVDTGIGMTK 16 1 P07900;P07900-2;G3V2J8;Q58FG1 P07900 HSP90AA1;HSP90AA4P Heat shock protein HSP 90-alpha;Putative heat shock protein HSP 90-alpha A4 2 0 QDRT(1)LT(0.969)IVDT(0.031)GIGMTK 79.07 0.011833 14130000 6342.1 8049.9 7593.3 6821.8 5382.4 6587.4 7815.3 5835 7241.6 10588 TRUE FALSE FALSE 5840.116093 8745.697486 7874.714378 6793.573199 5318.218395 5221.098985 8034.576284 7614.064639 6447.214598 10955.93221 0.53305515 0.798261373 0.718762605 0.620081712 0.485419067 0.476554517 0.733353961 0.694971865 0.588467916 1 13.41942462 -9.410357706 0.892528969 1.02477872 0.62469245 0 0.162968577 0.367658141 0.469264929 0.104726337 0.0207882 3.89E-10 9.410357706 -0.40008627 QDS(ph)DSDVVDIEEAEHDFMGEAHPVVFSR ddPTM_HeLa_Curcumin_4h_R1 2 QDSDSDVVDIEEAEHDFMGEAHPVVFSR 28 0 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 0 QDS(0.935)DS(0.065)DVVDIEEAEHDFMGEAHPVVFSR;QDS(0.924)DS(0.076)DVVDIEEAEHDFMGEAHPVVFSR ; 92.589 1.30E-07 10541900 2582.7 1579.59 1888.57 2279.32 2192.16 3181.61 2153.18 2022.51 2609.57 2260.12 TRUE FALSE FALSE 2378.27657 1716.122721 1958.562066 2269.888778 2166.019924 2521.708222 2213.592436 2639.163989 2323.3067 2338.659002 1.016940293 0.733806305 0.837472271 0.970594164 0.926180312 1.078271018 0.946522103 1.128494572 0.993435425 1 11.1914658 -1.730289595 1.297926925 0.970176277 136.1915906 0.202243321 0.096136325 2011.224301 4.887165495 0.015345492 808556.6207 0.018608459 1.730289595 135.2214143 QLSS(ph)GVSEIR ddPTM_HeLa_Curcumin_4h_R1 5 QLSSGVSEIR 10 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 0 QLS(0.212)S(0.628)GVS(0.16)EIR;QLS(0.086)S(0.907)GVS(0.006)EIR;QLS(0.031)S(0.782)GVS(0.187)EIR;QLS(0.025)S(0.767)GVS(0.208)EIR;QLS(0.051)S(0.504)GVS(0.444)EIR ;;;; 163.71 0.00059347 23855799000 10359.9 7852.82 9603.2 10114.1 9509.4 13856.2 20768.2 73530.2 5380.35 9258.2 TRUE FALSE FALSE 9539.902983 8531.582769 9959.10304 10072.25053 9396.006616 10982.26793 21350.8998 95949.21949 4790.139066 9579.921761 0.99582264 0.890569149 1.039580833 1.051391732 0.98080202 1.146383885 2.228713379 10.01565794 0.5000186 1 13.22579816 -4.243460917 2.927807986 1.00825802 11.77620278 0.995614954 0.179380358 0.012244665 0.143537607 0.016342795 0.31565877 5.71E-05 4.243460917 10.76794476 up QDS(ph)NRS(ph)EKEATPVVHETEPESGSQPR ddPTM_HeLa_Curcumin_4h_R1 1 QDSNRSEKEATPVVHETEPESGSQPR 26 2 E7EPN9;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;Q9Y520-2 E7EPN9 PRRC2C Protein PRRC2C 2 0 QDS(0.949)NRS(0.982)EKEAT(0.069)PVVHETEPESGSQPR 77.543 7.21E-05 5847400 2265.5 1874.8 1879.7 2025.9 2086.4 2408.1 1931.2 2568.2 2191.8 2009.7 TRUE FALSE FALSE 2086.183284 2036.849358 1949.363336 2017.517363 2061.521043 1908.632915 1985.384274 3351.232357 1951.365024 2079.536925 1.003196076 0.979472561 0.937402607 0.970176263 0.991336589 0.917816314 0.954724223 1.61152818 0.938365171 1 11.02204659 -4.259752801 24.99999886 0.985108652 1.611528389 0.971893432 0.032794417 17.46258914 258823.6973 0.004701503 0.040308425 5.50E-05 4.259752801 0.626419737 QDS(ph)RGSPLLGPVVPGPSPIPSVTEK ddPTM_HeLa_Curcumin_4h_R1 1 QDSRGSPLLGPVVPGPSPIPSVTEK 25 1 P49454 P49454 CENPF Centromere protein F 1 0 QDS(0.499)RGS(0.499)PLLGPVVPGPS(0.001)PIPS(0.001)VTEK 49.152 0.011146 13331000 1275.1 894.35 975.41 968.53 1020.4 1113.6 716.3 610.32 1221.4 1077.6 TRUE FALSE FALSE 1174.17449 971.6536289 1011.559553 964.5224795 1008.232396 882.6268071 736.3974502 796.4037584 1087.415476 1115.04652 1.053027357 0.871401876 0.907190449 0.865006493 0.904206577 0.791560524 0.66041859 0.714233661 0.975219828 1 10.12288819 -5.310933025 0.462712591 1.027739028 0.593341376 0.799193592 0.052681924 0.605012929 0.158825088 0.014586197 0.122540606 4.89E-06 5.310933025 -0.434397652 SES(ph)ENWR ddPTM_HeLa_Curcumin_4h_R1 2 SESENWR 7 0 Q6Y7W6-4;Q6Y7W6-5;Q6Y7W6;I1E4Y6;Q6Y7W6-3;E7ESB6;C9JHW1;C9JH78;C9IYH5 Q6Y7W6-4 GIGYF2 PERQ amino acid-rich with GYF domain-containing protein 2 1 0 S(0.027)ES(0.973)ENWR;S(0.003)ES(0.997)ENWR ; 106.88 0.016886 202786000 3281.7 1712.18 3290.7 3434.8 2785.7 4061.7 6103.2 20779.5 2174.36 2629.6 TRUE FALSE FALSE 3021.949982 1860.17321 3412.656237 3420.587708 2752.482347 3219.257635 6274.439366 27115.07389 1935.838148 2720.978404 1.110611528 0.683641299 1.254201882 1.257116816 1.011578167 1.183125022 2.305949711 9.965192612 0.711449288 1 11.40990979 -4.243101196 2.888968102 1.064173436 11.74720157 0.994502282 0.198196373 0.019494985 0.219470293 0.025145399 0.4944931 5.71E-05 4.243101196 10.68302813 up QDSKT(ph)LPAT(ph)CT(ph)S(ph)LR ddPTM_HeLa_Curcumin_4h_R1 1 QDSKTLPATCTSLR 14 1 Q9C0F0 Q9C0F0 ASXL3 Putative Polycomb group protein ASXL3 4 0 QDS(0.089)KT(0.988)LPAT(0.981)CT(0.981)S(0.959)LR 49.216 0.018479 18639000 6271.2 4756.8 7477.2 6475.2 8494.5 8026.7 7196.4 6666.8 6276.3 5709.6 TRUE FALSE FALSE 5774.827903 5167.956596 7754.31161 6448.407338 8393.208635 6361.87194 7398.311616 8699.47663 5587.805593 5908.008175 0.97745767 0.87473755 1.312508612 1.091468926 1.420649462 1.07682179 1.252251418 1.472488929 0.94580194 1 12.52845611 -6.754744649 24.99945183 0.980461265 1.259989071 0.621216527 0.121862654 81.8819237 305762.0958 0.017778983 0.024813702 1.76E-07 6.754744649 0.279527806 QDSRGS(ph)PLLGPVVPGPS(ph)PIPSVTEK ddPTM_HeLa_Curcumin_4h_R1 2 QDSRGSPLLGPVVPGPSPIPSVTEK 25 1 P49454 P49454 CENPF Centromere protein F 2 0 QDS(0.294)RGS(0.706)PLLGPVVPGPS(0.978)PIPS(0.019)VT(0.004)EK;QDS(0.386)RGS(0.614)PLLGPVVPGPS(0.983)PIPS(0.015)VT(0.001)EK ; 89.7 2.30E-05 16724700 3744.42 3220.77 3272 2900.45 3240.3 6041.5 5001.1 1457.3 3844.8 2928.56 TRUE FALSE FALSE 3448.045206 3499.159007 3393.263198 2888.448706 3201.661539 4788.424798 5141.417406 1901.624061 3423.035059 3030.327242 1.137845827 1.154713246 1.119767909 0.953180457 1.056539866 1.580167558 1.696654188 0.627530926 1.129592544 1 11.56525788 -5.304545754 24.20117256 1.068490161 1.34097134 0.119146209 0.270085164 379.3666634 212986.8871 0.035607397 0.079621194 4.96E-06 5.304545754 0.272481179 QDVDNAS(ph)LAR ddPTM_HeLa_Curcumin_4h_R1 2 QDVDNASLAR 10 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 1 0 QDVDNAS(1)LAR;QDVDNAS(1)LAR ; 122.46 0.0041406 105588000 4571.9 4195.1 4767.7 4765.3 4436 5833.3 5226.3 4195.2 4999.6 5057.3 TRUE FALSE FALSE 4210.029291 4557.705751 4944.395156 4745.582451 4383.103597 4623.407825 5372.935912 5474.297168 4451.156388 5233.040799 0.804509166 0.870947873 0.944841698 0.906849886 0.837582539 0.883503111 1.026733045 1.04610252 0.850586984 1 12.35343379 -4.736352249 7.607741938 0.89949297 1.037692629 0.545015021 0.053577288 0.157609281 34.74966639 0.010479428 0.038156369 1.84E-05 4.736352249 0.138199658 QDVDNASLAR ddPTM_HeLa_Curcumin_4h_R1 5 QDVDNASLAR 10 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 0 ;;;; ;;;; 178.54 1.18E-12 238399000 23766.6 19812.3 22260.6 22040.4 22849 27329 24172.6 23096.1 23764.6 19632 FALSE FALSE TRUE 21885.44853 21524.78693 23085.59742 21949.20266 22576.5406 21660.65734 24850.8181 30137.99457 21157.68284 20314.21054 1.077346742 1.059592589 1.136426019 1.080485142 1.111366871 1.06628103 1.223321874 1.483591721 1.041521293 1 14.31020168 -1 0.741331956 1.047804717 74.873466 0.912556872 0.038900383 76.48940502 0.321201222 0.007620733 9429.291541 0.1 1 73.82566128 QEAGDS(ph)PPPAPGT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 QEAGDSPPPAPGTPK 15 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 2 0 QEAGDS(1)PPPAPGT(1)PK;QEAGDS(1)PPPAPGT(1)PK ; 109.42 0.010314 23184000 7426.3 6660.8 6552.2 7381.6 7819.8 7564.2 6530.7 5898.7 7044.7 6774.6 TRUE FALSE FALSE 6838.500519 7236.529872 6795.030296 7351.056895 7726.553992 5995.299654 6713.933866 7697.186476 6271.914035 7010.016846 0.97553268 1.032312765 0.969331522 1.048650389 1.10221618 0.855247539 0.957762872 1.098026816 0.894707413 1 12.7752022 -2.210266526 11.20394175 0.995558621 1.090113097 0 0.076446372 0 0 0.008567754 0 0.006162167 2.210266526 0.094554476 QEAGDS(ph)PPPAPGTPK ddPTM_HeLa_Curcumin_4h_R1 1 QEAGDSPPPAPGTPK 15 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 0 QEAGDS(0.996)PPPAPGT(0.004)PK 149.42 0.00044955 29821000 4766.3 4891.1 5137.7 4647.1 4742.5 5187.8 3818.3 3791.2 4920.3 5430.4 TRUE FALSE FALSE 4389.042326 5313.86489 5328.107682 4627.871532 4685.948785 4111.791801 3925.431222 4947.119427 4380.5554 5619.105996 0.781092638 0.945677995 0.948212702 0.823595699 0.833931374 0.731751956 0.698586434 0.880410412 0.779582269 1 12.4561249 -5.805535104 1.941538589 0.901325714 0.767376553 0.263902589 0.081030972 0.327346373 2.510683274 0.014400057 0.031416011 1.56E-06 5.805535104 -0.133949161 QEAGDSPPPAPGT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 QEAGDSPPPAPGTPK 15 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 0 QEAGDSPPPAPGT(1)PK;QEAGDS(0.008)PPPAPGT(0.992)PK ; 199.41 9.89E-07 24929000 8236.8 6685.9 7461.6 7205.9 7410.7 8377.1 7294.9 4804.1 7727.7 6802.6 TRUE FALSE FALSE 7584.848589 7263.799404 7738.13346 7176.083895 7322.332243 6639.595031 7499.575261 6268.847975 6879.990644 7038.989844 1.077547881 1.031937759 1.099324425 1.019476381 1.040253276 0.943259641 1.065433454 0.890589149 0.977411645 1 12.78115269 -5.283277662 22.98274312 1.040761084 0.976328027 0.255585555 0.052319356 276.9132974 291425.1833 0.006940122 0.015536666 5.21E-06 5.283277662 -0.064433057 QEAGKEGTAPS(ph)ENGETK ddPTM_HeLa_Curcumin_4h_R1 2 QEAGKEGTAPSENGETK 17 1 Q15651;A0A087WZE9 Q15651 HMGN3 High mobility group nucleosome-binding domain-containing protein 3 1 0 QEAGKEGT(0.001)APS(0.986)ENGET(0.013)K;QEAGKEGTAPS(0.961)ENGET(0.039)K ; 80.016 0.0041165 20396600 4218.6 3394.5 3682.3 4168.2 4185.7 4941.2 3774 3703.3 4559.7 4462.8 TRUE FALSE FALSE 3884.693359 3687.905454 3818.769277 4150.953093 4135.788261 3916.339421 3879.888283 4832.419122 4059.512318 4617.881968 0.841228378 0.798614057 0.826952552 0.898886789 0.895602852 0.848081317 0.840187841 1.046457912 0.879085335 1 12.17301558 -9.290712747 1.044398237 0.999155342 0.868779534 0.011770405 0.074185264 0.439890605 0.867982968 0.041449534 0.011438493 5.12E-10 9.290712747 -0.130375807 QEAGKEGTAPS(ph)ENGETKAEEAQK ddPTM_HeLa_Curcumin_4h_R1 1 QEAGKEGTAPSENGETKAEEAQK 23 2 Q15651 Q15651 HMGN3 High mobility group nucleosome-binding domain-containing protein 3 1 0 QEAGKEGT(0.005)APS(0.937)ENGET(0.059)KAEEAQK 56.882 0.0031165 13520000 2981 2465.8 2561.7 2932.1 2493.4 3293.1 2540.1 3012.6 3229.6 3091.2 TRUE FALSE FALSE 2745.050704 2678.932765 2656.638856 2919.967747 2463.667833 2610.073939 2611.36837 3931.127872 2875.32096 3198.61897 0.85819872 0.837527942 0.830558088 0.912883896 0.770228607 0.816000269 0.816404953 1.229007865 0.898925751 1 11.64323343 -9.198382053 0.933891994 1.00019829 0.87316521 0.011985212 0.125604513 0.915634761 1.432994187 0.077864027 0.021787348 6.33E-10 9.198382053 -0.12703308 QEAIPDLEDS(ph)PPVS(ph)DSEEQQESAR ddPTM_HeLa_Curcumin_4h_R1 1 QEAIPDLEDSPPVSDSEEQQESAR 24 0 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 2 0 QEAIPDLEDS(1)PPVS(0.935)DS(0.063)EEQQES(0.002)AR 64.397 0.0031963 0 1398.4 1202.1 1203.2 1326.8 1400.4 1359.8 1281.7 987.72 1766.9 1274 TRUE FALSE FALSE 1287.715164 1306.004168 1247.79165 1321.310053 1383.701145 1077.762152 1317.661052 1288.871281 1573.075491 1318.271405 0.976820979 0.990694452 0.946536233 1.002305025 1.049632981 0.817557104 0.999537005 0.977697973 1.193286515 1 10.36443171 -6.590030431 0.180486226 1.008745894 0.939448733 0.084220213 0.083909245 12.56609521 1.357662296 0.168721893 0.295806185 2.57E-07 6.590030431 -0.069297162 QEAKPQQAAGMLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 QEAKPQQAAGMLSPK 15 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 QEAKPQQAAGMLS(1)PK;QEAKPQQAAGMLS(1)PK ; 108.25 0.0010557 121529000 8745.6 8315.9 9100.9 8730 10763.1 9637.5 8764.6 4193.8 7898.2 6931.4 TRUE FALSE FALSE 8053.376532 9034.689341 9438.18736 8693.877573 10634.75706 7638.573863 9010.511087 5472.470314 7031.78722 7172.265634 1.12284973 1.259670208 1.315928305 1.212152201 1.482761181 1.065015471 1.256299132 0.763004411 0.980413663 1 12.80821321 -8.01557553 1.159523662 1.02771964 1.204323471 0.152586339 0.178088189 0.553046593 1.555847301 0.043866948 0.03591868 9.65E-09 8.01557553 0.176603831 QEAS(ph)ESPVK ddPTM_HeLa_Curcumin_4h_R1 1 QEASESPVK 9 0 Q01167-2;Q01167;E9PPI7;Q01167-3 Q01167-2 FOXK2 Forkhead box protein K2 1 0 QEAS(0.661)ES(0.339)PVK 90.614 0.018636 5206400 1998.2 1998.2 2208 1847.9 2696.3 2499.4 1915.3 1986.2 2072.6 2354.8 TRUE FALSE FALSE 1840.040362 2170.915504 2289.830422 1840.253879 2664.148384 1980.996266 1969.038163 2591.783237 1845.240965 2436.629125 0.755158158 0.890950322 0.939753366 0.755245786 1.093374595 0.81300689 0.808099248 1.063675719 0.757292502 1 11.25067096 QEASES(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 2 QEASESPVK 9 0 Q01167-2;Q01167;E9PPI7;Q01167-3 Q01167-2 FOXK2 Forkhead box protein K2 1 0 QEAS(0.188)ES(0.812)PVK;QEAS(0.008)ES(0.992)PVK ; 120.55 0.0060926 63490000 6706.9 6996.7 7727.3 6591.1 8146.3 8566.8 7214.5 5359.4 6715.4 6495.2 TRUE FALSE FALSE 6176.041788 7601.463571 8013.680536 6563.827775 8049.160693 6789.949112 7416.919453 6993.456388 5978.737421 6720.907717 0.918929711 1.1310174 1.192350925 0.976628166 1.197629998 1.01027263 1.103559187 1.04055236 0.889572908 1 12.71444038 -7.259996014 24.9995075 0.961716807 1.093710498 0.479634626 0.073494913 87.97908042 1523825.985 0.011431465 0.013591155 5.50E-08 7.259996014 0.13199369 QEEAEEQGAGS(ph)PGQPAHLAR ddPTM_HeLa_Curcumin_4h_R1 1 QEEAEEQGAGSPGQPAHLAR 20 0 Q96S99 Q96S99 PLEKHF1 Pleckstrin homology domain-containing family F member 1 1 0 QEEAEEQGAGS(1)PGQPAHLAR 160.12 4.69E-06 9550100 2365.3 2426.1 2321.8 2138 2404.5 2763.8 2198.4 1716.8 2440.7 2244.5 TRUE FALSE FALSE 2178.084009 2635.801274 2407.84795 2129.153522 2375.827908 2190.556726 2260.081187 2240.244417 2172.961316 2322.496208 0.937820265 1.134900141 1.036750003 0.916752206 1.022963095 0.943190658 0.973125889 0.964584747 0.935614581 1 11.18146053 -5.22985416 24.85688007 0.986601229 0.961582985 0.0538874 0.060289149 2160.786643 1700489.072 0.008740397 0.022282777 5.89E-06 5.22985416 -0.025018244 QEEEAAQQGPVVVS(ph)PASDYKDK ddPTM_HeLa_Curcumin_4h_R1 3 QEEEAAQQGPVVVSPASDYKDK 22 1 I3L0X5;O75391;I3L4C3 I3L0X5 SPAG7 Sperm-associated antigen 7 1 0 QEEEAAQQGPVVVS(1)PASDYKDK;QEEEAAQQGPVVVS(0.965)PAS(0.034)DY(0.002)KDK;QEEEAAQQGPVVVS(0.905)PAS(0.041)DY(0.054)KDK ;; 130.62 7.04E-06 148408000 8068.96 7235.19 8403.46 8077.14 8558.92 11110.2 10030.46 8521.76 8467.87 7414.48 TRUE FALSE FALSE 7430.293302 7860.567584 8714.89962 8043.718935 8456.860469 8805.819282 10311.88771 11120.00539 7538.965847 7672.132628 0.968478214 1.024560962 1.135916184 1.048433249 1.102282883 1.147766822 1.344070575 1.449402133 0.982642795 1 12.90541195 -2.287221245 0.406065958 0.983560251 3.872646343 0.928683071 0.040545065 3.911277192 0.124130397 0.010400098 7.786087738 0.005161534 2.287221245 2.889086091 QEEEAAQQGPVVVS(ph)PASDYKDKYSHLIGK ddPTM_HeLa_Curcumin_4h_R1 1 QEEEAAQQGPVVVSPASDYKDKYSHLIGK 29 2 I3L0X5;O75391;I3L4C3 I3L0X5 SPAG7 Sperm-associated antigen 7 1 0 QEEEAAQQGPVVVS(0.647)PAS(0.18)DY(0.161)KDKY(0.005)S(0.006)HLIGK 52.674 0.0021584 20289000 1401.8 1115.1 1160.7 1424.3 914.07 2007.9 1163.8 1424.8 1590 1423.5 TRUE FALSE FALSE 1290.846051 1211.484275 1203.716563 1418.406624 903.1703122 1591.438906 1196.453096 1859.214961 1415.580978 1472.966519 0.876358039 0.822479167 0.817205651 0.962959175 0.613164183 1.080431147 0.812274468 1.262224862 0.961040838 1 10.52450892 -4.251810859 24.51463607 0.906603757 1.262225113 0.443639826 0.124926672 738.4745299 1880137.513 0.016600985 0.284907629 5.60E-05 4.251810859 0.355621357 QEEEDRDS(ph)PGPQVPDPK ddPTM_HeLa_Curcumin_4h_R1 1 QEEEDRDSPGPQVPDPK 17 1 M0R353;Q6NSJ2-2;Q6NSJ2 M0R353 PHLDB3 Pleckstrin homology-like domain family B member 3 1 0 QEEEDRDS(1)PGPQVPDPK 60.747 0.014687 6615900 2797.7 2255.6 2829.7 2258.3 2252.1 2293.9 1817.3 1115.1 2962.7 2356.9 TRUE FALSE FALSE 2576.259093 2450.564013 2934.571171 2248.955753 2225.245178 1818.119282 1868.288547 1455.088857 2637.699222 2438.8021 1.056362504 1.004822824 1.203283847 0.922155903 0.912433682 0.74549685 0.766068123 0.596640809 1.081555253 1 11.25195698 -5.29295834 1.198018491 1.036617213 0.65455482 0.825958283 0.07183791 0.159123757 0.407331977 0.010704467 0.04688398 5.09E-06 5.29295834 -0.382062393 QEEEQDLDGEKGPSSEGPEEEDGEGFS(ph)FKYSPGK ddPTM_HeLa_Curcumin_4h_R1 1 QEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGK 34 2 P84157-2;P84157-3;P84157 P84157-2 MXRA7 Matrix-remodeling-associated protein 7 1 0 QEEEQDLDGEKGPS(0.017)S(0.054)EGPEEEDGEGFS(0.748)FKY(0.077)S(0.104)PGK 48.163 0.0038083 8091700 1690.7 1658.8 1418.5 1776.2 1477.3 2094 1549.5 1134.3 1897.5 1491.1 TRUE FALSE FALSE 1556.879311 1802.179281 1471.070858 1768.850555 1459.684162 1659.680796 1592.9748 1480.142848 1689.348997 1542.915614 1.009050201 1.168034897 0.953435719 1.146433764 0.946055733 1.075678268 1.032444539 0.95931549 1.094906929 1 10.59144344 -1.03183009 21.56794991 1.020768583 0.004130183 0 0.077838206 0 0 0.008780959 0 0.09293299 1.03183009 -1.0166384 QEEGADAS(ph)EEDPTPAGEEDVKDAR ddPTM_HeLa_Curcumin_4h_R1 1 QEEGADASEEDPTPAGEEDVKDAR 24 1 Q86X53;E5RHA3;H0YB25 Q86X53 ERICH1 Glutamate-rich protein 1 1 0 QEEGADAS(0.995)EEDPT(0.005)PAGEEDVKDAR 115.47 3.11E-07 15159000 2060.7 2038 2108.8 2239.4 2440 2216.7 1677 1110.8 1876.7 1727.3 TRUE FALSE FALSE 1897.593421 2214.155639 2186.953983 2230.133956 2410.904594 1756.931433 1724.052107 1449.477807 1670.830705 1787.323546 1.06169553 1.238810759 1.223591547 1.24775056 1.348890971 0.98299574 0.964599896 0.810976731 0.934822746 1 10.8035851 -4.612081655 2.150849447 1.096154317 0.82475194 0.370358004 0.130185743 0.385349625 3.08087393 0.020726265 0.151730976 2.44E-05 4.612081655 -0.271402376 QEEMNS(ph)QQEEEEMETDAR ddPTM_HeLa_Curcumin_4h_R1 2 QEEMNSQQEEEEMETDAR 18 0 E9PPJ0;Q13435;H0YCG1;E9PJ04 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 0 QEEMNS(1)QQEEEEMETDAR;QEEMNS(1)QQEEEEMETDAR ; 103.99 0.00047097 10835100 3650.7 2465.3 2781.1 3294.9 2435.6 3508.7 2944.1 3934.7 3193.2 2489.9 TRUE FALSE FALSE 3361.743243 2678.389547 2884.170013 3281.266577 2406.557061 2780.956069 3026.703522 5134.371917 2842.913949 2576.42384 1.304809865 1.039576449 1.119447029 1.273574063 0.934068775 1.079386096 1.174769258 1.992828912 1.103434111 1 11.33115423 -4.261889246 4.917891034 1.128301592 2.037330798 0.855447237 0.108366021 0.056867095 4.117092565 0.018260236 0.175561266 5.47E-05 4.261889246 0.909029205 QEETAVLEEDS(ph)ADWEK ddPTM_HeLa_Curcumin_4h_R1 2 QEETAVLEEDSADWEK 16 0 Q96A49 Q96A49 SYAP1 Synapse-associated protein 1 1 0 QEET(0.29)AVLEEDS(0.71)ADWEK;QEETAVLEEDS(1)ADWEK ; 164.02 4.43E-11 3473500 2426.1 1720.93 2220.8 1948.33 2583.1 2475.7 1659.58 1092.28 2324.48 2126.31 TRUE FALSE FALSE 2234.071625 1869.679521 2303.104802 1940.268327 2552.29822 1962.211913 1706.143348 1425.311144 2069.49036 2200.199114 1.015395202 0.849777417 1.046771079 0.881860334 1.160030564 0.891833789 0.775449521 0.647810071 0.940592306 1 11.10341838 -4.725953603 2.29786097 0.997990817 0.666897781 0.622848597 0.085043151 0.129122076 1.280727001 0.010669003 0.058344586 1.88E-05 4.725953603 -0.331093037 QEGHLDSES(ph)PTNIPLTK ddPTM_HeLa_Curcumin_4h_R1 2 QEGHLDSESPTNIPLTK 17 0 Q9H7P9-3;Q9H7P9;H7BXC7;E7ESZ3 Q9H7P9-3 PLEKHG2 Pleckstrin homology domain-containing family G member 2 1 0 QEGHLDS(0.013)ES(0.738)PT(0.25)NIPLTK;QEGHLDSES(0.902)PT(0.098)NIPLTK ; 92.805 0.0016725 24853400 13173 10601.4 10298.3 11638.5 10649 11993.5 8935.4 5704.8 13343.1 11050.9 TRUE FALSE FALSE 12130.34315 11517.73778 10679.96406 11590.34297 10522.01763 9505.912905 9186.103276 7444.167258 11879.39531 11434.91795 1.060815932 1.007242713 0.933978197 1.013592141 0.920165556 0.831305738 0.803337926 0.65100312 1.038870184 1 13.48115839 -4.217885097 0.553612558 1.028140901 0.391982758 0.930131338 0.032416181 0.744562024 0.148208712 0.00708885 0.307171312 6.06E-05 4.217885097 -0.636158142 QEGHLDSESPT(ph)NIPLTK ddPTM_HeLa_Curcumin_4h_R1 1 QEGHLDSESPTNIPLTK 17 0 Q9H7P9-3;Q9H7P9;H7BXC7;E7ESZ3 Q9H7P9-3 PLEKHG2 Pleckstrin homology domain-containing family G member 2 1 0 QEGHLDS(0.014)ES(0.38)PT(0.606)NIPLTK 97.256 0.002565 7187900 5100.7 3731.7 4350.1 4099.8 5029.6 5985.2 3388.1 2424 5617.3 4435.9 TRUE FALSE FALSE 4696.974213 4054.25152 4511.318533 4082.836114 4969.625305 4743.802053 3483.160967 3163.066441 5001.096244 4590.047195 1.023295407 0.883270116 0.982847962 0.889497633 1.082695906 1.033497446 0.758850796 0.689114143 1.089552249 1 12.16429327 -4.688698481 4.8756084 0.997739247 0.708802643 0.734799482 0.066202982 0.066727738 2.888106818 0.008294726 0.032731756 2.05E-05 4.688698481 -0.288936605 RMS(ph)GEPIQTVESIR ddPTM_HeLa_Curcumin_4h_R1 2 RMSGEPIQTVESIR 14 1 Q5VT52-2;Q5VT52-3;Q5VT52 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 RMS(1)GEPIQTVESIR;RMS(1)GEPIQTVESIR ; 74.789 0.016438 16611600 3991.4 3234 3010 3406.7 3339.7 4465.2 4073.6 5572.8 3529.4 3412.6 TRUE FALSE FALSE 3675.476478 3513.53255 3121.553248 3392.603978 3299.876259 3539.067187 4187.894252 7271.921066 3142.23365 3531.187596 1.040861291 0.995000252 0.883995303 0.960754388 0.934494747 1.002231428 1.185973313 2.059341473 0.889851803 1 11.78593775 -4.242680721 2.589205296 0.997358115 2.310696942 0.97074883 0.056703116 0.058785794 0.481528908 0.007639638 0.170715397 5.72E-05 4.242680721 1.313338827 up GPPQS(ph)PVFEGVYNNSR ddPTM_HeLa_Curcumin_4h_R1 3 GPPQSPVFEGVYNNSR 16 0 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3;H3BUF6;H3BSK9;Q8WWM7-7 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 0 GPPQS(1)PVFEGVYNNSR;GPPQS(1)PVFEGVYNNSR;GPPQS(1)PVFEGVYNNSR ;; 175.16 4.17E-05 553699000 3948.5 3715.06 3640.51 3644.38 4228.21 5110.88 4050.33 6595.2 3998.56 3453.85 TRUE FALSE FALSE 3635.972059 4036.173232 3775.430503 3629.300521 4177.791357 4050.825877 4163.971359 8606.046119 3559.927972 3573.87103 1.017376404 1.129356151 1.056398082 1.015509651 1.168982127 1.133456088 1.165115172 2.408046078 0.996098612 1 11.80327186 -4.242586193 3.310644915 1.040548167 2.625941031 0.97623024 0.062430987 0.04132318 0.704148915 0.010024004 0.169994161 5.72E-05 4.242586193 1.585392863 up QEKPSSPS(ph)PMPSSTPSPSLNLGNTEEAIR ddPTM_HeLa_Curcumin_4h_R1 1 QEKPSSPSPMPSSTPSPSLNLGNTEEAIR 29 1 O95810 O95810 SDPR Serum deprivation-response protein 1 0 QEKPS(0.058)S(0.182)PS(0.588)PMPS(0.119)S(0.039)T(0.013)PSPSLNLGNTEEAIR 60.029 0.003068 0 528.49 447.77 340.3 480.04 387.03 456.06 450.04 342.36 312.08 416.64 TRUE FALSE FALSE 486.6594588 486.4732436 352.9118174 478.0537217 382.41492 361.4680151 462.6669112 446.743988 277.8456048 431.118209 1.128830675 1.128398739 0.818596408 1.108869242 0.887030313 0.838442932 1.073178774 1.036244767 0.644476617 1 8.751939688 -6.800186759 24.99984752 1.067603697 0.963390793 0 0.164919703 193.822893 125054.0408 0.016179723 0.021264529 1.58E-07 6.800186759 -0.104212904 QELEEICHDLEAR ddPTM_HeLa_Curcumin_4h_R1 1 QELEEICHDLEAR 13 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 175.6 0.00017125 1721600 1188.1 1154.3 1115.6 1298.9 1249 1253.7 937.51 1128.3 1350 1350.7 FALSE FALSE TRUE 1094.060631 1254.072549 1156.945117 1293.525496 1234.106491 993.6684879 963.8140074 1472.313476 1201.908378 1397.636724 0.782793277 0.897280764 0.827786718 0.925509092 0.88299518 0.71096335 0.689602663 1.053430731 0.859957639 1 10.44877371 -9.430516073 1.064334464 1.00358658 0.836253952 0.01968456 0.109082559 0.578775987 1.131606159 0.075068719 0.017267871 3.71E-10 9.430516073 -0.167332627 QELESLMK ddPTM_HeLa_Curcumin_4h_R1 2 QELESLMK 8 0 Q9Y250-5;Q9Y250-4;Q9Y250-3;Q9Y250-2;Q9Y250 Q9Y250-5 LZTS1 Leucine zipper putative tumor suppressor 1 0 0 ; ; 98.629 0.014671 2484900 929.82 916.87 1298.47 1137.4 1121.68 229.11 688.95 766.78 1326.95 978.16 FALSE FALSE TRUE 856.2237659 996.1201573 1346.59244 1132.69374 1108.304699 181.5900034 708.2800828 1000.567692 1181.386905 1012.150987 0.845944703 0.984161622 1.330426446 1.119095624 1.094999375 0.179409995 0.6997771 0.988555764 1.167204221 1 9.983208804 -5.329305634 24.99999944 0.985514258 0.630284829 0.410828923 0.231942761 149.1203188 54931.33999 0.033346542 0.074565145 4.68E-06 5.329305634 -0.355229429 QELLEALTK ddPTM_HeLa_Curcumin_4h_R1 1 QELLEALTK 9 0 P12956;P12956-2;B1AHC9 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 0 114.83 0.002044 793260 611.76 727.84 634.97 708.26 764.94 734.22 434.81 488.94 644.36 600.14 FALSE FALSE TRUE 563.3385505 790.7512464 658.5025468 705.3294078 755.8185901 581.9344956 447.0095984 638.0155552 573.6753201 620.9948203 0.907154991 1.273362064 1.060399419 1.135805621 1.217109331 0.937100402 0.719828224 1.027408819 0.923800491 1 9.278437425 -3.887310002 20.0929029 0.995655162 6.863488224 0 0.155730682 6492.954313 1128474.845 0.02193864 44274.47958 0.000129625 3.887310002 5.867833062 QELMEK(ac)ETAK(ac)PK ddPTM_HeLa_Curcumin_4h_R1 1 QELMEKETAKPK 12 2 O43823 O43823 AKAP8 A-kinase anchor protein 8 0 2 QELMEK(1)ETAK(1)PK 82.379 0.0027891 0 0 0 0 127.47 149.21 171.33 72.267 0 70.019 0 FALSE TRUE FALSE 0 0 0 126.9425629 147.4307682 135.7942267 74.29461752 0 62.33809088 0 0 QEMASASSSQR ddPTM_HeLa_Curcumin_4h_R1 1 QEMASASSSQR 11 0 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8VZ49;A0A2R8Y4L2;H0YH80;Q32P51 F8W6I7 HNRNPA1;HNRNPA1L2 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;Heterogeneous nuclear ribonucleoprotein A1-like 2" 0 0 136.02 0.00039205 354070 254.46 302.69 212.4 112.11 130.74 325.15 291.71 0 223.58 343.75 FALSE FALSE TRUE 234.3192225 328.8531748 220.2717308 111.6461185 129.1810109 257.7102248 299.8945975 0 199.0538334 355.6952869 0.658763923 0.924536217 0.619270873 0.313881355 0.363178866 0.724525273 0.843122213 0 0.559618979 1 8.474498048 -13.4278413 0.074273869 2.621062631 3.80E-09 0.12347784 0.271883028 154.8087638 0.905110875 42.57110728 5.654370425 3.73E-14 13.4278413 -2.621062628 QEMEK(ac)MTKK ddPTM_HeLa_Curcumin_4h_R1 1 QEMEKMTKK 9 2 P40222;Q9NUQ3;Q9NUQ3-2 P40222;Q9NUQ3 TXLNA;TXLNG Alpha-taxilin;Gamma-taxilin 0 1 QEMEK(1)MTKK 131.62 0.00095575 5926500 1370.2 802.79 1101.4 1043.4 1236.4 1966.1 1388.9 1160.8 1180 1116.2 FALSE TRUE FALSE 1261.747224 872.1795904 1142.218853 1039.082687 1221.656738 1558.308697 1427.868796 1514.722576 1050.556952 1154.987867 1.092433315 0.755141777 0.98894446 0.899648141 1.057722572 1.349199193 1.236263027 1.311461895 0.909582674 1 10.17366198 -5.350662685 4.973150479 1.006319538 1.292002883 0.698249653 0.099625238 0.110656015 4.570852702 0.014883825 0.034196299 4.46E-06 5.350662685 0.285683344 QEMEKMTK ddPTM_HeLa_Curcumin_4h_R1 1 QEMEKMTK 8 1 P40222;Q9NUQ3;Q9NUQ3-2 P40222;Q9NUQ3 TXLNA;TXLNG Alpha-taxilin;Gamma-taxilin 0 0 64.265 0.009568 0 993.23 738.66 726.03 959.87 894.09 1117.3 865.92 920.55 1025.6 919.62 FALSE FALSE TRUE 914.6147974 802.506479 752.9373105 955.8983123 883.4285607 885.5593854 890.2153847 1201.221457 913.0942459 951.5767265 0.961157174 0.843343954 0.791252339 1.0045415 0.928383951 0.930623207 0.935516138 1.262348504 0.959559246 1 9.894176177 -4.259607717 24.66883965 0.951665953 1.26234863 0.684656696 0.066329664 69.68394902 938410.1706 0.010225479 0.0883366 5.50E-05 4.259607717 0.310682676 QEMQEVQSS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 QEMQEVQSSR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 1 0 QEMQEVQS(0.421)S(0.579)R;QEMQEVQS(0.068)S(0.932)R ; 120.6 0.0044622 24367000 7279.9 6038.8 5762 5906.6 6032.5 7245.8 6025.7 6329.2 7317.7 5923.5 TRUE FALSE FALSE 6703.688233 6560.766964 5975.544789 5882.160054 5960.566377 5742.939403 6194.764925 8258.943944 6514.966618 6129.341184 1.093704532 1.070386974 0.974908169 0.95967248 0.972464446 0.936958676 1.010673862 1.34744399 1.062914663 1 12.5815163 -4.260114122 24.77881259 1.022937766 1.347444109 0.797137372 0.050777318 42.01731064 785512.5858 0.008580677 0.07189237 5.49E-05 4.260114122 0.324506343 QEMQEVQSSR ddPTM_HeLa_Curcumin_4h_R1 7 QEMQEVQSSR 10 0 P22626;P22626-2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 ;;;;;; ;;;;;; 181.87 8.30E-16 593804000 13848 11287.4 11527.8 11806.4 11734.5 15763.1 13196.7 13033.2 13285.6 12495.9 FALSE FALSE TRUE 12751.91619 12263.03256 11955.03041 11757.54825 11594.57375 12493.65537 13566.96388 17006.96268 11828.20292 12930.13159 0.986217046 0.948407406 0.924586909 0.909313889 0.896709648 0.966243482 1.049251803 1.315296953 0.914778232 1 13.65844934 -4.270329842 2.512931562 0.971009436 1.386551668 0.880262184 0.040483671 0.144752415 1.151391802 0.006486189 0.126820104 5.37E-05 4.270329842 0.415542233 QENCGAQQVPAGPGTST(ph)PPS(ph)SPVR ddPTM_HeLa_Curcumin_4h_R1 1 QENCGAQQVPAGPGTSTPPSSPVR 24 0 Q96G46-2;Q96G46 Q96G46-2 DUS3L tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like 2 0 QENCGAQQVPAGPGT(0.011)S(0.436)T(0.557)PPS(0.674)S(0.322)PVR 139.64 2.77E-06 17633000 1628.4 1688.4 1723.6 1844.5 1857 1980.5 1500.3 2949 1536.1 1536 TRUE FALSE FALSE 1499.510422 1834.337773 1787.478132 1836.867948 1834.856488 1569.721975 1542.39438 3848.136524 1367.593673 1589.375886 0.943458646 1.154124578 1.124641533 1.155716508 1.154450942 0.987634196 0.97044028 2.421162017 0.860459559 1 10.63424465 -4.260209898 24.99758909 1.019997447 2.421162467 0.944598265 0.100325287 16.82567682 342055.8451 0.014302343 0.118564579 5.49E-05 4.260209898 1.40116502 QENGAS(ph)VILR ddPTM_HeLa_Curcumin_4h_R1 1 QENGASVILR 10 0 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PRY8;A0A087X1X7;P29692-4;E9PL12;E9PPR1;E9PK06;E9PIZ1;E9PK72;E9PMW7;H0YCK7 P29692;E9PMW7 EEF1D Elongation factor 1-delta 1 0 QENGAS(1)VILR 92.856 0.017318 6935800 1664.8 1630.1 1507.6 1823.5 1805.4 2523.2 1817.5 2306 1999.8 1902.4 TRUE FALSE FALSE 1533.029323 1770.99858 1563.472982 1815.95484 1783.871784 1999.859878 1868.494158 3009.088784 1780.426943 1968.508258 0.778777187 0.899665304 0.794242531 0.922503034 0.906204877 1.015926588 0.949192949 1.528613747 0.904454902 1 10.94288705 -1.857643699 1.163624014 0.890413361 200 0.87091989 0.071722137 151.3741098 0.84288797 0.013670681 79711.15324 0.01387894 1.857643699 199.1095866 QEPCAQHNGSEPAS(ph)PKR ddPTM_HeLa_Curcumin_4h_R1 1 QEPCAQHNGSEPASPKR 17 1 Q8N6T7-2;Q8N6T7;M0QZ09 Q8N6T7-2 SIRT6 NAD-dependent protein deacetylase sirtuin-6 1 0 QEPCAQHNGSEPAS(1)PKR 147.17 0.00012154 5082500 284.31 524.09 563.96 383.55 574.73 767.68 358.04 418.08 487.84 515.73 TRUE FALSE FALSE 261.8065635 569.3900043 584.8608537 381.9629717 567.8767201 608.4545145 368.0856388 545.5506674 434.3251725 533.6515791 0.490594563 1.066969586 1.095960129 0.715753474 1.06413387 1.140171862 0.689748992 1.022297485 0.813874051 1 9.059754304 -7.222090799 24.99907636 0.759447283 0.965033633 0.20023989 0.185023812 766.790882 487160.8467 0.038316767 0.04692791 6.00E-08 7.222090799 0.20558635 QEPES(ph)EEEEEEKQEK ddPTM_HeLa_Curcumin_4h_R1 2 QEPESEEEEEEKQEK 15 1 P49756 P49756 RBM25 RNA-binding protein 25 1 0 QEPES(1)EEEEEEKQEK;QEPES(1)EEEEEEKQEK ; 93.371 0.0027252 353100000 8701.1 8196 9209.7 8176.6 10193.6 9436.7 8304 7610.3 8423.3 7922 TRUE FALSE FALSE 8012.398754 8904.425719 9551.019584 8142.767396 10072.04798 7479.422046 8536.987891 9930.645436 7499.285064 8197.28891 0.977444963 1.086264717 1.165143706 0.993348836 1.228704769 0.912426307 1.041440406 1.211454854 0.914849427 1 13.00093113 -7.256578838 22.95771906 0.989349009 1.086823656 0.264285831 0.094241437 149.3142038 705252.1592 0.014197378 0.017072509 5.54E-08 7.256578838 0.097474647 QEPES(ph)EEEEEEKQEKEEK ddPTM_HeLa_Curcumin_4h_R1 1 QEPESEEEEEEKQEKEEK 18 2 P49756 P49756 RBM25 RNA-binding protein 25 1 0 QEPES(1)EEEEEEKQEKEEK 46.121 0.017434 333980000 5565.7 4819.5 5625.4 5265.1 5956.4 5879.2 5114.3 4826.3 5066.8 4833.7 TRUE FALSE FALSE 5125.168972 5236.076105 5833.882273 5243.314411 5885.37382 4659.787648 5257.793494 6297.816652 4510.984717 5001.670715 1.024691401 1.046865418 1.166386715 1.048312596 1.176681584 0.931646226 1.051207445 1.259142597 0.901895581 1 12.28819437 -1.000000004 0.114692453 0.95683322 1.505727674 0.294219382 0.088626624 116.6772893 0.92969263 0.424022415 10.22056036 0.099999999 1.000000004 0.548894454 QEPGGS(ph)HGSETEDTGR ddPTM_HeLa_Curcumin_4h_R1 1 QEPGGSHGSETEDTGR 16 0 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 0 QEPGGS(0.762)HGS(0.234)ET(0.003)EDTGR 100.69 0.0027301 6876600 1347.9 1347.6 1328.6 1356.6 1527.1 1298.4 1537.9 1397.1 1385.5 1043.5 TRUE FALSE FALSE 1241.212293 1464.080539 1377.839085 1350.986749 1508.89033 1029.097204 1581.049335 1823.069359 1233.514116 1079.761547 1.149524444 1.355929504 1.276058671 1.251189906 1.397429214 0.953078211 1.464257862 1.688399965 1.142394929 1 10.07649703 -1 0.122893327 0.894117158 2.83564342 0.386846178 0.164419459 58.54138997 0.492091292 0.662812482 19.60178841 0.1 1 1.941526262 QEPIES(ph)DEEEAEPPREVEPGQR ddPTM_HeLa_Curcumin_4h_R1 2 QEPIESDEEEAEPPREVEPGQR 22 1 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 0 QEPIES(1)DEEEAEPPREVEPGQR;QEPIES(1)DEEEAEPPREVEPGQR ; 82.479 0.00032142 121010000 1898.17 1451.63 1268.95 1239.91 1466.66 1528.44 1395.7 1159.13 1493.15 1313.44 TRUE FALSE FALSE 1747.927842 1577.102429 1315.978403 1234.779581 1449.171037 1211.424315 1434.859586 1512.543401 1329.355181 1359.081942 1.286109238 1.16041747 0.968284812 0.908539465 1.066286728 0.891354875 1.055756493 1.112915531 0.978127322 1 10.40841673 -6.763605032 24.99851171 1.140780474 0.996879597 0.167006489 0.104540208 63.23459094 729931.3512 0.019734276 0.026659517 1.72E-07 6.763605032 -0.143900877 QEPLEEDS(ph)PSSSSAGLDK ddPTM_HeLa_Curcumin_4h_R1 3 QEPLEEDSPSSSSAGLDK 18 0 P15408;P15408-3;P15408-2;C9JCN8 P15408 FOSL2 Fos-related antigen 2 1 0 QEPLEEDS(0.978)PS(0.018)S(0.004)SSAGLDK;QEPLEEDS(0.982)PS(0.018)SSSAGLDK;QEPLEEDS(0.973)PS(0.027)SSSAGLDK ;; 260.49 1.08E-42 205422000 6075.3 4783.6 4914.5 6032.6 5565 6573.4 5760.3 6216.4 5950.5 4623.2 TRUE FALSE FALSE 5594.433594 5197.073069 5096.635693 6007.6387 5498.64101 5210.002743 5921.918515 8111.751743 5297.745037 4783.855856 1.169440251 1.086377438 1.065382371 1.255815158 1.149416114 1.08908021 1.23789652 1.695651372 1.107421544 1 12.2239582 -4.230922072 2.167396799 1.09845101 1.885844637 0.871888451 0.066343107 0.218205136 1.069325761 0.011771104 0.340498073 5.88E-05 4.230922072 0.787393627 SAESPTSPVTS(ph)ETGSTFK ddPTM_HeLa_Curcumin_4h_R1 1 SAESPTSPVTSETGSTFK 18 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 SAES(0.004)PT(0.004)S(0.005)PVT(0.073)S(0.747)ET(0.127)GS(0.032)T(0.008)FK 84.821 0.0046988 4519000 679.81 732.38 582.32 557.68 683.48 921.37 1137.6 3855 663.97 534.52 TRUE FALSE FALSE 626.0023212 795.6836638 603.9012915 555.3724679 675.3299474 730.267476 1169.517994 5030.371754 591.1341522 553.0945302 1.131817957 1.438603386 1.091859092 1.004118532 1.221002759 1.320330316 2.114499295 9.094958418 1.068775987 1 9.111382264 -4.24257896 3.002485879 1.118068285 10.60091086 0.996339709 0.143360654 0.020136684 0.254023663 0.024614664 0.465118227 5.72E-05 4.24257896 9.482842574 up QEPLGS(ph)DSEGVNCLAYDEAIMAQQDR ddPTM_HeLa_Curcumin_4h_R1 3 QEPLGSDSEGVNCLAYDEAIMAQQDR 26 0 J3KR44;F5GYJ8;Q96FW1;F5H6Q1;F5H3F0 J3KR44 OTUB1 Ubiquitin thioesterase OTUB1 1 0 QEPLGS(0.972)DS(0.028)EGVNCLAYDEAIMAQQDR;QEPLGS(0.907)DS(0.093)EGVNCLAYDEAIMAQQDR;QEPLGS(0.678)DS(0.322)EGVNCLAYDEAIMAQQDR ;; 111.38 4.49E-08 16051500 4142.54 3058.17 3521.13 4152.6 4530.3 4611.9 3925.34 3064.39 4070.7 3335.81 TRUE FALSE FALSE 3814.653588 3322.504588 3651.626175 4135.417641 4476.279131 3655.339953 4035.474476 3998.708404 3624.154394 3451.729149 1.105142792 0.962562369 1.057912141 1.198071304 1.296822241 1.058988059 1.169116782 1.158465288 1.049953295 1 11.75310355 -6.304267355 6.568494012 1.04329733 1.176051532 0.543881381 0.064461366 0.149584741 17.85331604 0.010691934 0.016497814 4.96E-07 6.304267355 0.132754202 QEPLGSDS(ph)EGVNCLAYDEAIMAQQDR ddPTM_HeLa_Curcumin_4h_R1 1 QEPLGSDSEGVNCLAYDEAIMAQQDR 26 0 J3KR44;F5GYJ8;Q96FW1;F5H6Q1;F5H3F0 J3KR44 OTUB1 Ubiquitin thioesterase OTUB1 1 0 QEPLGS(0.105)DS(0.895)EGVNCLAYDEAIMAQQDR 182.78 4.65E-15 7661300 616.19 698.12 781.88 753.46 865.43 1043.1 755.79 604.87 638.1 736.22 TRUE FALSE FALSE 567.4179113 758.462382 810.8571606 750.3423822 855.1103125 826.7493018 776.9954333 789.2920785 568.1020264 761.8035902 0.744834914 0.995614082 1.064391362 0.984955167 1.122481337 1.085252567 1.019941942 1.036083432 0.745732934 1 9.573275277 -7.022781023 14.34628139 0.879013997 1.050502263 0.594887709 0.079009633 2.689662485 1693.717729 0.016342954 0.020237045 9.49E-08 7.022781023 0.171488265 QEPQS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 QEPQSPSR 8 0 K7ENY9;Q8WUQ7;Q8WUQ7-2 K7ENY9 CACTIN Cactin 1 0 QEPQS(0.932)PS(0.068)R 99.539 0.015323 7010800 1889.8 2574.9 1898.5 1648.7 1746.3 2039.6 1422.2 1633.1 1603.3 1739.7 TRUE FALSE FALSE 1740.220336 2797.462882 1968.86008 1641.878116 1725.476513 1616.563969 1462.103104 2131.024672 1427.422001 1800.154446 0.966706129 1.554012707 1.093717311 0.91207625 0.958515819 0.898014042 0.812209812 1.183801022 0.792944186 1 10.81390497 -6.253981093 23.75928776 1.043134388 0.94236614 0.074964262 0.203034273 749.8086128 2388598.101 0.029821151 0.048764773 5.57E-07 6.253981093 -0.100768248 QEQALLEEIER ddPTM_HeLa_Curcumin_4h_R1 2 QEQALLEEIER 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 199.7 3.66E-05 7618600 2331.4 2021.52 2277 2292.41 2638.6 2707.7 2102.24 1987.29 2297 1939.53 FALSE FALSE TRUE 2146.86723 2196.251181 2361.387623 2282.924615 2607.136418 2146.092498 2161.223197 2593.205573 2045.024847 2006.928523 1.069727798 1.094334529 1.1766177 1.137521635 1.299067898 1.069341769 1.076881001 1.292126522 1.018982402 1 10.97077352 -7.356182167 0.770805286 1.015859487 1.174591762 0.450124176 0.073146353 0.378048784 0.467702765 0.018630981 0.020891912 4.40E-08 7.356182167 0.158732274 QEQIAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 QEQIAKR 7 1 P62753;A2A3R5 P62753 RPS6 40S ribosomal protein S6 0 1 QEQIAK(1)R 80.165 0.017493 889370 594.5 541.85 611.29 421.35 639.69 564.49 558.56 507.9 566.74 466.33 FALSE TRUE FALSE 547.4446977 588.6850996 633.9449451 419.6065653 632.0621145 447.4084109 574.2316903 662.7563719 504.5700399 482.5349328 1.134518271 1.219984419 1.313780417 0.869587955 1.30987846 0.927204189 1.190031335 1.373488896 1.04566531 1 8.914489579 -13.52287874 0.182496048 0.287053156 1.194815446 0.117190128 0.154212666 79.18089089 0.91590681 19.89776234 0.193911042 3.00E-14 13.52287874 0.90776229 QEQINTEPLEDT(ph)VLSPTKK ddPTM_HeLa_Curcumin_4h_R1 1 QEQINTEPLEDTVLSPTKK 19 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 0 QEQINT(0.007)EPLEDT(0.541)VLS(0.42)PT(0.032)KK 67.655 0.0061823 31662000 3913.2 2957.9 3312.8 3151.3 3572.4 3885.5 2888.5 1800.5 3075.8 2955.1 TRUE FALSE FALSE 3603.466091 3213.567696 3435.575282 3138.260756 3529.801463 3079.603501 2969.543536 2349.464162 2738.392435 3057.789505 1.178454594 1.050944707 1.123548654 1.026316805 1.154363784 1.00713391 0.9711406 0.768353792 0.895546417 1 11.57827338 -4.135856753 1.230207023 1.086015879 0.556228394 0.516826759 0.081238318 0.887879081 0.918510107 0.01050165 0.639630093 7.31E-05 4.135856753 -0.529787485 QEQINTEPLEDTVLS(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 2 QEQINTEPLEDTVLSPTK 18 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 0 QEQINTEPLEDT(0.002)VLS(0.941)PT(0.057)K;QEQINTEPLEDTVLS(0.5)PT(0.5)K ; 270.49 2.97E-117 209360000 13897.6 10599.5 12487.8 12398 12514.2 15065.6 12395 6505.6 13666.8 11769 TRUE FALSE FALSE 12797.5903 11515.67355 12950.60885 12346.70036 12364.97634 11940.82474 12742.77034 8489.127492 12167.58623 12177.97187 1.050880264 0.945615056 1.063445456 1.013855221 1.015355961 0.980526549 1.046378697 0.697088775 0.999147178 1 13.57198627 -4.258457638 24.99764216 1.018836232 0.697088657 0.887023776 0.033739817 61.39264151 514662.9504 0.004486049 0.042074187 5.51E-05 4.258457638 -0.321747575 QEQINTEPLEDTVLSPT(ph)K ddPTM_HeLa_Curcumin_4h_R1 2 QEQINTEPLEDTVLSPTK 18 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 0 QEQINTEPLEDTVLS(0.413)PT(0.587)K;QEQINTEPLEDTVLS(0.385)PT(0.615)K ; 168.12 1.26E-05 75688900 9265.6 7237.1 8558.8 8741.4 8084.5 10324.2 7991 4345.5 9465.2 6985.8 TRUE FALSE FALSE 8532.217983 7862.642676 8875.996657 8705.230403 7988.097618 8182.844542 8215.205953 5670.422946 8426.891241 7228.55603 1.180348876 1.087719683 1.227907292 1.204283451 1.105075147 1.132016479 1.136493363 0.784447533 1.165777951 1 12.81949177 -4.25874615 24.8036886 1.111396137 0.784447402 0.706934068 0.066317017 126.2189357 1162356.978 0.01173589 0.107929199 5.51E-05 4.25874615 -0.326948734 QEQLS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 QEQLSPR 7 0 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 QEQLS(1)PR 99.53 0.020011 77751000 6847.4 4719.3 5486.8 4951.5 5303.4 3647.1 2193.8 1751.6 5700.5 4405.6 TRUE FALSE FALSE 6305.421065 5127.215263 5690.145635 4931.012005 5240.160419 2890.650349 2255.352124 2285.654777 5075.169412 4558.694272 1.383163838 1.124711366 1.248196368 1.081672012 1.149487135 0.63409612 0.494736429 0.501383651 1.113294533 1 12.15440494 -5.204554424 2.83864906 1.179572186 0.501176529 0.891778198 0.098491822 0.085500924 1.351157493 0.020812728 0.059525963 6.24E-06 5.204554424 -0.678395656 QEQMCNVGVS(ph)MGLT(ph)RS(ph)MQVVPLDK ddPTM_HeLa_Curcumin_4h_R1 1 QEQMCNVGVSMGLTRSMQVVPLDK 24 1 Q9BVP2-2;Q9BVP2 Q9BVP2-2 GNL3 Guanine nucleotide-binding protein-like 3 3 0 QEQMCNVGVS(1)MGLT(1)RS(1)MQVVPLDK 40.094 0.0091681 0 397.51 528.44 510.46 364.38 486.35 576.85 439.87 389.93 485.69 315.86 TRUE FALSE FALSE 366.046664 574.1159989 529.3780966 362.8722921 480.5505939 457.2048076 452.2115684 508.817862 432.4110221 326.8361115 1.119970074 1.756586799 1.619705039 1.110257647 1.470310584 1.398880942 1.383603441 1.556798175 1.323020948 1 8.352423583 -7.434796559 7.523442777 1.052477127 1.456618334 0.370562927 0.18208019 0.148806124 11.22297689 0.028111439 0.032003861 3.67E-08 7.434796559 0.404141207 QERLS(ph)PEVAPPAHR ddPTM_HeLa_Curcumin_4h_R1 2 QERLSPEVAPPAHR 14 1 Q8TAD8 Q8TAD8 SNIP1 Smad nuclear-interacting protein 1 1 0 QERLS(1)PEVAPPAHR;QERLS(1)PEVAPPAHR ; 77.191 0.0097701 256092800 6689.1 5460.8 6213.7 5938 6609.9 7660.4 5562.7 5050.82 7565 5511.8 TRUE FALSE FALSE 6159.650677 5932.807219 6443.985188 5913.430129 6531.08126 6071.546689 5718.774391 6590.791767 6735.138427 5703.33464 1.080008638 1.040234809 1.12986272 1.036837307 1.145133798 1.064560836 1.002707145 1.155603201 1.18091237 1 12.47758997 -9.298958486 0.527669207 0.982826262 1.082557964 0 0.073632959 1.406614037 0.529790372 0.07208533 0.010960225 5.02E-10 9.298958486 0.099731702 QES(ph)DPEDDDVKKPALQSSVVATSK ddPTM_HeLa_Curcumin_4h_R1 2 QESDPEDDDVKKPALQSSVVATSK 24 2 Q9H307 Q9H307 PNN Pinin 1 0 QES(0.978)DPEDDDVKKPALQS(0.013)S(0.01)VVATSK;QES(0.928)DPEDDDVKKPALQS(0.035)S(0.035)VVAT(0.001)S(0.001)K ; 62.858 0.0027724 1050780000 3989.5 3284.7 3662.6 3822.7 4148.6 4049.3 3547.2 3048.2 3598.6 3254.2 TRUE FALSE FALSE 3673.726865 3568.614832 3798.339178 3806.88268 4099.130655 3209.429535 3646.724885 3977.582148 3203.842583 3367.283208 1.091006203 1.059790523 1.128012984 1.130550193 1.217340628 0.953121355 1.082987281 1.181243722 0.951462169 1 11.71736935 -8.923964054 0.502902429 0.986649606 1.109162203 0.354172778 0.068911276 1.368881205 0.572881954 0.080232281 0.018838471 1.19E-09 8.923964054 0.122512597 QET(ph)VADFTPK ddPTM_HeLa_Curcumin_4h_R1 1 QETVADFTPK 10 0 O75400-2;O75400-3;O75400;F5H578 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 0 QET(0.584)VADFT(0.416)PK 115 0.015806 12919000 6474 6874.4 6726 7923.4 8934 5219 6697 7983.4 6467.7 4860 TRUE FALSE FALSE 5961.576069 7468.592504 6975.271477 7890.61507 8827.467885 4136.52057 6884.899796 10417.50191 5758.209491 5028.884638 1.185466857 1.485138961 1.387041457 1.569058676 1.75535303 0.822552289 1.369070935 2.071533284 1.145027159 1 12.29602274 -7.515309153 1.080940708 1.04943508 1.485038735 0.250795567 0.30161818 0.426974734 1.007992868 0.06722402 0.070566021 3.05E-08 7.515309153 0.435603656 TNSGISSASGGSTEPT(ph)TPDSERPAQALLR ddPTM_HeLa_Curcumin_4h_R1 2 TNSGISSASGGSTEPTTPDSERPAQALLR 29 1 A2A2F0;Q86X10-4;Q86X10-2;Q86X10-3;Q86X10;A0A0J9YW54 A2A2F0 RALGAPB Ral GTPase-activating protein subunit beta 1 0 TNSGISSASGGS(0.001)T(0.003)EPT(0.461)T(0.461)PDS(0.073)ERPAQALLR;TNSGISSAS(0.003)GGS(0.006)T(0.021)EPT(0.455)T(0.455)PDS(0.059)ERPAQALLR ; 96.287 7.17E-08 34370000 1168.18 808.56 1027.78 1141.75 849.93 1302.71 1225.76 1744.68 1182.2 951.02 TRUE FALSE FALSE 1075.71732 878.4483235 1065.870431 1137.025741 839.7951399 1032.513261 1260.151527 2276.6249 1052.515618 984.0678742 1.093133257 0.892670462 1.083126946 1.155434265 0.85339148 1.049229721 1.280553466 2.313483612 1.069555917 1 9.942614016 -4.242234369 2.463506776 1.031694708 2.639178255 0.951246926 0.087303019 0.08274863 0.588848509 0.012018631 0.284689883 5.72E-05 4.242234369 1.607483547 up LGSDFGS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 LGSDFGSSR 9 0 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 0 LGS(0.108)DFGS(0.891)S(0.001)R 112.11 0.0084696 5836500 1099.5 1026.8 1224.8 1295.2 1361.4 1202.5 826.7 211.95 1208.8 1153 TRUE FALSE FALSE 1012.473415 1115.552017 1270.192165 1289.840806 1345.166194 953.087945 849.8949771 276.5725793 1076.197664 1193.066664 0.848631049 0.935029073 1.064644754 1.081113775 1.127486195 0.798855566 0.712361683 0.231816534 0.902043194 1 10.22045894 -4.289199605 1.577896766 0.958991353 9.33E-14 0.857140435 0.093240576 0.317417561 0.762092249 0.015716127 0.459641926 5.14E-05 4.289199605 -0.958991353 down QEYDESGPS(ph)IVHR ddPTM_HeLa_Curcumin_4h_R1 2 QEYDESGPSIVHR 13 0 P60709;Q6S8J3;A5A3E0;P0CG38;A0A2R8YFE2;Q9BYX7;P0CG39;P63261 P60709;P63261 ACTB;POTEE;POTEF;POTEI;POTEKP;POTEJ;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;POTE ankyrin domain family member J;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 1 0 QEYDESGPS(1)IVHR;QEYDESGPS(1)IVHR ; 167.93 8.85E-05 67285000 11230.6 8842.7 9593.3 10544.3 11987.7 9413.6 8406.7 8286.2 10513.1 8439.9 TRUE FALSE FALSE 10341.68616 9607.023586 9948.836137 10500.67048 11844.75451 7461.113247 8642.569377 10812.62424 9359.839232 8733.185897 1.184182529 1.10005944 1.139198942 1.202387148 1.356292497 0.854340367 0.989623887 1.238107646 1.07175541 1 13.09229233 -3.684665641 5.379804197 1.098531453 8.186842731 0.092606364 0.129685292 2130.232693 811.2609338 0.018858526 179269.0253 0.000206697 3.684665641 7.088311278 QEYDESGPSIVHR ddPTM_HeLa_Curcumin_4h_R1 6 QEYDESGPSIVHR 13 0 P60709;Q6S8J3;A5A3E0;P0CG38;A0A2R8YFE2;Q9BYX7;P0CG39;P63261 P60709;P63261 ACTB;POTEE;POTEF;POTEI;POTEKP;POTEJ;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;POTE ankyrin domain family member J;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 0 0 ;;;;; ;;;;; 244.71 3.22E-27 899168500 28541.6 24825.6 23492.1 22079.5 38898.6 31980.4 25708.9 25127.2 29858 22559.5 FALSE FALSE TRUE 26282.50224 26971.41424 24362.73789 21988.14088 38434.7596 25347.30455 26430.22254 32788.36761 26582.6521 23343.44095 1.12590523 1.155417246 1.04366524 0.941940862 1.64649075 1.085842683 1.132233359 1.404607302 1.138763225 1 14.51072962 QEYDESGPSIVHRK ddPTM_HeLa_Curcumin_4h_R1 4 QEYDESGPSIVHRK 14 1 P60709;Q6S8J3;A5A3E0;P0CG38;A0A2R8YFE2;Q9BYX7;P0CG39;P63261 P60709;P63261 ACTB;POTEE;POTEF;POTEI;POTEKP;POTEJ;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;POTE ankyrin domain family member E;POTE ankyrin domain family member F;POTE ankyrin domain family member I;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;POTE ankyrin domain family member J;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 0 0 ;;; ;;; 69.229 0.0049099 77353000 29415.3 20102.4 21041.5 20184.7 29186.9 29817.1 21764.8 25101.2 35284 23984.5 FALSE FALSE TRUE 27087.04797 21839.96188 21821.3165 20101.18106 28838.86528 23632.69735 22375.46171 32754.44033 31413.43348 24817.95959 1.091429288 0.880006344 0.879255058 0.809944951 1.162015966 0.952241753 0.901583453 1.319787802 1.265754075 1 14.59909689 -4.249977613 24.58720375 1.001405565 1.31978804 0.342885709 0.135084904 1078.008851 2312436.727 0.015684269 0.327664046 5.62E-05 4.249977613 0.318382475 QFAEMYVAK ddPTM_HeLa_Curcumin_4h_R1 1 QFAEMYVAK 9 0 P13639 P13639 EEF2 Elongation factor 2 0 0 119.75 0.001372 1228300 819.43 1001.6 778.53 944.9 924.11 770.57 735.3 587.26 965.92 760.58 FALSE FALSE TRUE 754.5712508 1088.173841 807.3830067 940.9902542 913.0905918 610.7450959 755.930539 766.3128706 859.9609926 787.0100984 0.958782171 1.382668206 1.025886464 1.195652071 1.160201875 0.776032096 0.960509326 0.973701446 1.092693721 1 9.620238337 -5.265220725 24.99333477 1.041452145 0.909123797 0.226843752 0.137931967 499.2195269 3299672.912 0.021295458 0.0493928 5.43E-06 5.265220725 -0.132328349 QFGVY(ph)PGMVGSGASS(ph)S(ph)CPNK ddPTM_HeLa_Curcumin_4h_R1 1 QFGVYPGMVGSGASSSCPNK 20 0 O15090 O15090 ZNF536 Zinc finger protein 536 3 0 QFGVY(1)PGMVGS(0.276)GAS(0.427)S(0.73)S(0.566)CPNK 47.113 0.018806 4197500 2551.7 2048.7 2224.8 2565.8 2366.7 2665.2 2261 1906.4 2388.3 1813.9 TRUE FALSE FALSE 2349.730252 2225.780499 2307.253045 2555.183399 2338.478648 2112.407477 2324.437575 2487.652584 2126.309465 1876.93289 1.251898917 1.185860459 1.229267736 1.361361087 1.245904241 1.125457116 1.238423381 1.325381742 1.132863874 1 10.87416135 -9.283684843 0.598084056 0.960430595 1.248803834 0.447006499 0.073700905 0.547682968 0.279383167 0.087421102 0.01462873 5.20E-10 9.283684843 0.288373239 QFHLTDDDLLR ddPTM_HeLa_Curcumin_4h_R1 1 QFHLTDDDLLR 11 0 E9PGM4;Q04446 E9PGM4 GBE1 "1,4-alpha-glucan-branching enzyme" 0 0 134.98 0.00042102 0 1536.2 1837.1 1479.2 1428.6 1598 1879.6 1381.3 1177.8 1709.1 1660.4 FALSE FALSE TRUE 1414.608149 1995.890738 1534.020453 1422.688832 1578.944894 1489.749773 1420.05556 1536.905798 1521.616006 1718.098776 0.823356706 1.161685676 0.89285929 0.828059976 0.919007053 0.86709204 0.82652731 0.894538672 0.885639421 1 10.74659727 -6.53219735 24.99920913 0.937143383 0.866961012 0.199567283 0.087514439 368.7905992 989359.3074 0.015473703 0.021899652 2.94E-07 6.53219735 -0.070182371 QFKIFS(ph)DFR ddPTM_HeLa_Curcumin_4h_R1 2 QFKIFSDFR 9 1 M9MMK7;Q0VDD8-2;Q0VDD8-4 M9MMK7 DNAH14 1 0 QFKIFS(1)DFR;QFKIFS(1)DFR ; 111.17 0.0038352 164410000 6211.5 3641.1 4577.2 4236.3 4408.8 6312 4367.3 3984.8 4796.4 4474.5 TRUE FALSE FALSE 5719.853221 3955.82046 4746.835059 4218.771313 4356.227939 5002.820049 4489.834684 5199.747176 4270.24692 4629.988542 1.235392522 0.854390983 1.025236891 0.911183964 0.940872294 1.080525363 0.969729113 1.123058325 0.922301833 1 12.17679291 -7.263563115 24.99974588 1.111157577 0.98625148 0 0.108597864 216.1898465 2544891.465 0.018571026 0.0218018 5.45E-08 7.263563115 -0.124906097 QFLISPPAS(ph)PPVGWK ddPTM_HeLa_Curcumin_4h_R1 2 QFLISPPASPPVGWK 15 0 H0YF64;V9GYW9;E9PD55;E9PDJ2;Q9UKA8-6;P53805-4;P53805-3;Q9UKA8-5;P53805-2;Q9UKA8-2;Q9UKA8;P53805 H0YF64 RCAN3;RCAN1 Calcipressin-3;Calcipressin-1 1 0 QFLIS(0.006)PPAS(0.994)PPVGWK;QFLIS(0.38)PPAS(0.62)PPVGWK ; 118.5 0.0014361 32614000 5356.6 5588.1 4663.9 4449.4 5582.7 9009.7 6495 2468.1 6556.3 5678.6 TRUE FALSE FALSE 4932.619458 6071.110464 4836.748237 4430.989562 5516.129949 7140.98666 6677.23222 3220.612328 5837.090293 5875.930927 0.839461784 1.033216785 0.823145863 0.754091499 0.938766983 1.215294521 1.136370101 0.548102483 0.993389876 1 12.52060172 -5.510049634 24.88176898 0.909817913 0.999144398 0.011630071 0.183316035 1559.802853 3025197.588 0.025527008 0.054641781 3.09E-06 5.510049634 0.089326485 QFLLQQASGLSS(ph)PGNNDSK ddPTM_HeLa_Curcumin_4h_R1 1 QFLLQQASGLSSPGNNDSK 19 0 B7ZBM3;Q8IVH2-3;Q8IVH2-2;Q8IVH2;A2A312 B7ZBM3 FOXP4 Forkhead box protein P4 1 0 QFLLQQASGLS(0.102)S(0.898)PGNNDSK 164.2 1.32E-15 0 2217.2 1543.9 1426.4 1748.9 1715.3 3006 2524.8 1565.1 1936.9 1505.6 TRUE FALSE FALSE 2041.70628 1677.347837 1479.263639 1741.663515 1694.846168 2382.521715 2595.639093 2042.291785 1724.426916 1557.919488 1.310533886 1.076658871 0.94951225 1.117941927 1.087890729 1.529297075 1.666093218 1.310909711 1.10687807 1 10.60540496 -5.259216841 24.73405066 1.123648734 1.518499352 0.697525201 0.122201923 88.56744357 985634.0329 0.021063391 0.050949091 5.51E-06 5.259216841 0.394850618 QFREDDFR ddPTM_HeLa_Curcumin_4h_R1 1 QFREDDFR 8 1 P34897-3;P34897-2;P34897;H0YIZ0 P34897-3 SHMT2 "Serine hydroxymethyltransferase, mitochondrial;Serine hydroxymethyltransferase" 0 0 93.162 0.016432 4949700 2449.8 1803.7 1736.6 2769.5 2337.2 3399.2 2100.6 1810.3 2631.2 1844.8 FALSE FALSE TRUE 2255.895745 1959.603791 1800.959924 2758.040543 2309.330416 2694.167603 2159.537183 2362.252136 2342.563943 1908.906663 1.181773729 1.026558202 0.943451012 1.444827344 1.20976602 1.41136686 1.131295325 1.237489597 1.227175738 1 10.89853085 -6.267246478 24.98909493 1.072920751 1.280925758 0.455296652 0.115365172 330.6677452 1422928.875 0.017259613 0.026806246 5.40E-07 6.267246478 0.208005007 QFS(ph)ALVPAFDPRPGR ddPTM_HeLa_Curcumin_4h_R1 1 QFSALVPAFDPRPGR 15 1 A0A087X2H1;Q9ULT8;H0YJP0;H0YJD4 A0A087X2H1 HECTD1 E3 ubiquitin-protein ligase HECTD1 1 0 QFS(1)ALVPAFDPRPGR 73.722 0.010509 12122000 1849.5 1363.5 1814.4 2053.9 1856.5 2510.9 2140.6 2998.1 1916 2005 TRUE FALSE FALSE 1703.110123 1481.354864 1881.64326 2045.401506 1834.36245 1990.111036 2200.659475 3912.206888 1705.819594 2074.673601 0.820905092 0.714018274 0.906958694 0.985890747 0.884169177 0.959240545 1.060725636 1.885697532 0.822211066 1 11.01866867 -4.18737197 2.241981272 0.903167888 2.264422164 0.927672318 0.083214169 0.174558736 0.845330661 0.013585653 0.502355751 6.50E-05 4.18737197 1.361254276 QFSNISFSRDS(ph)PEENVQSNK ddPTM_HeLa_Curcumin_4h_R1 1 QFSNISFSRDSPEENVQSNK 20 1 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7;H7C269 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 0 QFS(0.001)NIS(0.006)FS(0.019)RDS(0.974)PEENVQSNK 77.969 0.0013771 6859200 1683.3 1530.4 1371.9 1457.1 1731.3 1641.8 1669.3 944.28 1934.3 1454.6 TRUE FALSE FALSE 1550.065029 1662.680957 1422.743821 1451.070906 1710.655378 1301.272173 1716.136065 1232.186625 1722.112129 1505.147242 1.029842786 1.104663325 0.945252253 0.964072395 1.136536899 0.86454809 1.140178195 0.818648562 1.144148613 1 10.55568891 -4.235524674 24.36963077 1.016966608 0.818648198 0.316151424 0.092179143 4900.909088 4608612.271 0.009812793 1.00388632 5.81E-05 4.235524674 -0.198318409 RPS(ph)ASSPNNNTAAK ddPTM_HeLa_Curcumin_4h_R1 1 RPSASSPNNNTAAK 14 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 0 RPS(0.424)AS(0.152)S(0.424)PNNNTAAK 71.402 0.014513 3872000 1188.3 1031.8 1028.6 1400.2 1183.6 1420.9 860.02 221.99 1550.1 988.15 TRUE FALSE FALSE 1094.244801 1120.984194 1066.720821 1394.406343 1169.486343 1126.189323 884.1498466 289.6737291 1380.057908 1022.488139 1.070178479 1.096329778 1.043259848 1.363738405 1.143765192 1.101420428 0.864704257 0.283302777 1.349705542 1 9.997868392 -4.288109015 2.412043995 1.074017582 0.127146903 0.78869203 0.131919949 0.15248045 1.116865235 0.015567154 0.29134142 5.15E-05 4.288109015 -0.946870679 down LVSPGS(ph)ANETSSILVESVTR ddPTM_HeLa_Curcumin_4h_R1 3 LVSPGSANETSSILVESVTR 20 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;A0A0A0MT44 O75369-8 FLNB Filamin-B 1 0 LVS(0.324)PGS(0.676)ANETSSILVESVTR;LVS(0.001)PGS(0.999)ANETSSILVESVTR;LVS(0.076)PGS(0.924)ANETSSILVESVTR ;; 230.67 2.15E-25 82302000 4062.11 3177.4 3844.36 4152.94 3676.6 5120.24 4569.79 9898.2 3770.49 3282.9 TRUE FALSE FALSE 3740.589707 3452.040298 3986.835363 4135.756235 3632.758946 4058.244507 4698.006008 12916.11561 3356.87668 3396.980531 1.101151353 1.016208444 1.173640922 1.217480111 1.069408233 1.19466228 1.382994682 3.802234219 0.988194265 1 11.73003723 -4.241929927 3.10546129 1.078996922 4.290412661 0.990381336 0.079512731 0.028721812 0.40071823 0.012564149 0.229787025 5.73E-05 4.241929927 3.211415739 up QFTQS(ph)PETEASADSFPDTK ddPTM_HeLa_Curcumin_4h_R1 2 QFTQSPETEASADSFPDTK 19 0 O15061;H0YL34;A0A075B7B1;O15061-2 O15061 SYNM Synemin 1 0 QFT(0.061)QS(0.939)PETEASADSFPDTK;QFT(0.014)QS(0.965)PET(0.021)EASADSFPDTK ; 137.24 6.58E-05 12100300 8783.2 6843.4 7004.3 7739.1 7540.1 9069.5 6595.9 7453.2 8624.9 6848.3 TRUE FALSE FALSE 8088.000452 7434.913002 7263.88552 7707.077655 7450.189232 7188.383466 6780.963202 9725.64637 7678.770048 7086.277915 1.141360888 1.049198619 1.025063596 1.087605898 1.051354367 1.014408911 0.956914657 1.372461888 1.083611191 1 12.79081233 -4.250177289 24.78531266 1.055429426 1.372462097 0.794531168 0.049650318 650.2868588 1431104.687 0.008579676 0.177853432 5.62E-05 4.250177289 0.317032671 QFVPIKVEQIEAGTPGR ddPTM_HeLa_Curcumin_4h_R1 1 QFVPIKVEQIEAGTPGR 17 1 E2QRB9;E9PIR7;F8W809;A0A087WSW9;A0A182DWI3;A0A087WSY9;Q16881-7;Q16881-5;Q16881-2;Q16881-4;Q16881-3;Q16881-6;Q16881 E2QRB9 TXNRD1 "Thioredoxin reductase 1, cytoplasmic" 0 0 120.21 0.00015011 1686900 1689 1461.9 1323.1 1257.5 1596.5 2127.9 1322.2 1333.8 2089.9 1635.2 FALSE FALSE TRUE 1555.313868 1588.260122 1372.13525 1252.296798 1577.46278 1686.549554 1359.297373 1740.46948 1860.643199 1692.023078 0.919203696 0.938675212 0.810943578 0.740118036 0.932293892 0.9967651 0.803356285 1.028632235 1.099655922 1 10.72453353 -8.349850853 0.782983673 0.991497092 0.888136331 0.267856916 0.091455795 0.703434714 0.914370154 0.034164794 0.019161411 4.47E-09 8.349850853 -0.103360761 QFVTPADVVSGNPK ddPTM_HeLa_Curcumin_4h_R1 1 QFVTPADVVSGNPK 14 0 P13797;A0A0A0MSQ0;P13797-3;P13797-2;H7C4N2;Q14651 P13797 PLS3;PLS1 Plastin-3;Plastin-1 0 0 194.98 3.19E-56 0 1080.7 614.56 942.46 1019.6 938.79 1139 688.78 963.73 800.37 866.38 FALSE FALSE TRUE 995.1614547 667.679828 977.3883967 1015.381165 927.5955424 902.7585608 708.105313 1257.566841 712.5714134 896.4866405 1.11006836 0.744773874 1.090243125 1.132622751 1.03470091 1.006996111 0.789867111 1.402772539 0.794848893 1 9.808138274 QFYINVEREEWK ddPTM_HeLa_Curcumin_4h_R1 1 QFYINVEREEWK 12 1 P60842;J3KT12;P60842-2;J3KSZ0;J3KTB5;J3QS69;J3KTN0;J3QL43;E7EQG2;Q14240;Q14240-2 P60842 EIF4A1;EIF4A2 "Eukaryotic initiation factor 4A-I;Eukaryotic initiation factor 4A-II;Eukaryotic initiation factor 4A-II, N-terminally processed" 0 0 103.43 0.0064952 20947000 950.86 831.58 759.11 878.36 630.8 943.43 1104.3 904.11 982.59 1054.5 FALSE FALSE TRUE 875.5984277 903.4580698 787.2432844 874.7255791 623.278122 747.7519834 1135.283686 1179.768977 874.8023353 1091.143797 0.802459245 0.827991757 0.721484452 0.801659306 0.571215383 0.68529188 1.040452862 1.081222274 0.801729651 1 10.09162552 -9.095730161 0.815045183 1.002868291 0.80789795 0 0.156171541 0.922180876 1.087484361 0.1104365 0.030872076 8.02E-10 9.095730161 -0.194970341 QFYNQT(ph)Y(ph)GS(ph)RK ddPTM_HeLa_Curcumin_4h_R1 1 QFYNQTYGSRK 11 1 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 3 0 QFY(0.416)NQT(0.589)Y(0.995)GS(1)RK 58.433 0.015949 11949000 1123.9 800.81 901.45 1025.7 906.09 1180.4 961.81 946.66 1066 1151.7 TRUE FALSE FALSE 1034.942129 870.0284481 934.85853 1021.455925 895.2854685 935.5717342 988.7958 1235.292276 949.062467 1191.721489 0.868442953 0.730060216 0.784460579 0.857126379 0.751253944 0.785059045 0.829720542 1.036561216 0.796379419 1 10.2188314 -8.457417904 0.887554028 0.985625574 0.822357764 0 0.100563557 0.385040311 0.627972751 0.031179283 0.017340224 3.49E-09 8.457417904 -0.16326781 QGAIYHGLATLLNQPS(ph)PMMQR ddPTM_HeLa_Curcumin_4h_R1 1 QGAIYHGLATLLNQPSPMMQR 21 0 A8MQ02;J3KN01;P55196-3;P55196;P55196-5;Q5TIG5;P55196-2;P55196-6;P55196-1 A8MQ02 MLLT4 Afadin 1 0 QGAIYHGLAT(0.133)LLNQPS(0.867)PMMQR 68.771 0.001651 12582000 1132.7 934.84 1196.8 919.09 857.64 1572.6 1083.6 817.81 1030.1 1215.9 TRUE FALSE FALSE 1043.0456 1015.643404 1241.154461 915.2870491 847.4132031 1246.425033 1114.0029 1067.156504 917.1006072 1258.152434 0.829029592 0.807249882 0.986489734 0.72748502 0.673537784 0.990678871 0.885427607 0.848193331 0.728926466 1 10.29709101 -9.233752197 0.782647346 1.00913932 0.842553223 0 0.12588545 0.797359985 0.80396961 0.083863987 0.018886195 5.84E-10 9.233752197 -0.166586097 QGANINEIR ddPTM_HeLa_Curcumin_4h_R1 2 QGANINEIR 9 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 0 0 ; ; 99.136 0.010676 7372900 4157.4 3638.2 3676.7 3616 4081.7 4535.8 3515.5 3228 4100.1 3918.2 FALSE FALSE TRUE 3828.337403 3952.669796 3812.961736 3601.03795 4033.028393 3595.023951 3614.135469 4212.20234 3650.329288 4054.357158 0.944252628 0.974918993 0.940460247 0.888189622 0.994739298 0.886706279 0.891420101 1.038932234 0.900347243 1 11.98525747 -9.210699748 0.460157619 1.013980798 0.938067873 0 0.056114631 2.287075362 0.667361878 0.081090041 0.013086621 6.16E-10 9.210699748 -0.075912925 QGCDCECLGGGR ddPTM_HeLa_Curcumin_4h_R1 2 QGCDCECLGGGR 12 0 Q9NRX4-2;Q9NRX4 Q9NRX4-2 PHPT1 14 kDa phosphohistidine phosphatase 0 0 ; ; 169.82 1.22E-06 2951900 976.65 901.66 944.21 848.69 936.43 1066.68 708.8 981.13 1136.78 915.32 FALSE FALSE TRUE 899.3471219 979.5954727 979.2032532 845.1783457 925.2636839 845.438544 728.6870204 1280.27202 1012.078078 947.1273019 0.949552526 1.034280683 1.033866568 0.892359817 0.976915861 0.892634541 0.769365447 1.351742282 1.068576606 1 9.887414539 -9.706786927 1.593032575 1.000031677 0.972165284 0 0.145252947 3.251510265 14.85911597 0.094298398 0.02064467 1.96E-10 9.706786927 -0.027866393 QGDETPS(ph)TNNGSDDEKTGLK ddPTM_HeLa_Curcumin_4h_R1 1 QGDETPSTNNGSDDEKTGLK 20 1 Q9Y3P9;C9JGR5;B5MCD9;Q9Y3P9-4;Q9Y3P9-3 Q9Y3P9 RABGAP1 Rab GTPase-activating protein 1 1 0 QGDET(0.024)PS(0.479)T(0.479)NNGS(0.019)DDEKTGLK 87.468 0.00069254 11366000 2790.9 2120.1 2404.1 2874.4 2426.8 2537.9 1986.8 1592.1 2855.7 2108.9 TRUE FALSE FALSE 2569.99732 2303.351997 2493.198061 2862.506494 2397.861995 2011.510932 2042.544261 2077.523961 2542.436855 2182.184118 1.177717911 1.055525965 1.142524153 1.311762134 1.098835783 0.921787908 0.936009131 0.952038805 1.165088149 1 11.09155712 -5.266914941 21.00355868 1.106436162 0.936551619 0.53797075 0.081497624 38.21919736 146609.6305 0.013985466 0.032274095 5.41E-06 5.266914941 -0.169884543 QGDETPSTNNGS(ph)DDEKTGLK ddPTM_HeLa_Curcumin_4h_R1 1 QGDETPSTNNGSDDEKTGLK 20 1 Q9Y3P9;C9JGR5;B5MCD9;Q9Y3P9-4;Q9Y3P9-3 Q9Y3P9 RABGAP1 Rab GTPase-activating protein 1 1 0 QGDETPST(0.001)NNGS(0.994)DDEKT(0.004)GLK 86.641 0.0007479 31235000 6481.7 5216.3 6127.1 5844 6056.4 6882.1 5037.6 4952.8 6592.4 5861.8 TRUE FALSE FALSE 5968.666606 5667.173729 6354.175716 5819.819076 5984.181386 5454.674883 5178.941498 6462.88592 5869.230213 6065.497114 0.98403585 0.934329639 1.04759356 0.959495812 0.986593724 0.899295603 0.853836281 1.06551628 0.967642075 1 12.56641017 -5.325033364 9.499153762 0.989226084 0.931020889 0.09409802 0.057421819 0.577271604 83.70294237 0.007387742 0.016547814 4.73E-06 5.325033364 -0.058205196 QGDGK(ac)WHLVYR ddPTM_HeLa_Curcumin_4h_R1 1 QGDGKWHLVYR 11 1 Q99829;Q5JX60;F2Z2V0;A6PVH9;E7ENH5;Q5JX45;Q5JX52;Q5JX44;Q5JX61;Q5JX59;Q5JX58;B0QZ18 Q99829 CPNE1 Copine-1 0 1 QGDGK(1)WHLVYR 101.93 0.010788 2965400 1746.8 1571.3 1895.4 1458.6 1620.9 2998 2180.2 2526.9 2238.9 2130 FALSE TRUE FALSE 1608.538937 1707.11617 1965.645191 1452.5647 1601.571826 2376.181006 2241.370544 3297.340178 1993.298271 2204.017341 0.729821361 0.774547522 0.891846518 0.659053208 0.726660265 1.078113571 1.016947781 1.49605909 0.904393189 1 11.10591986 -3.975505631 1.168043585 0.843362438 2.173814224 0.752090822 0.115260079 1.25422562 0.902402269 0.020692562 2.376965666 0.000105802 3.975505631 1.330451786 QGDQDVSLHFVLWGCLHVY(ph)QRMIDK ddPTM_HeLa_Curcumin_4h_R1 1 QGDQDVSLHFVLWGCLHVYQRMIDK 25 1 A0A384DVU0;Q8IY17-2;Q8IY17-3;Q8IY17 A0A384DVU0 PNPLA6 Neuropathy target esterase 1 0 QGDQDVS(0.018)LHFVLWGCLHVY(0.982)QRMIDK 43.176 0.00795 0 855.56 629.74 685.83 793.01 724.84 658.77 613.83 355.18 821.59 754.64 TRUE FALSE FALSE 787.8415232 684.1719195 711.2474631 789.7287347 716.1967564 522.1336761 631.0524178 463.472747 731.4636325 780.8636838 1.008936053 0.876173311 0.910847153 1.011352879 0.917185382 0.668661748 0.808146711 0.593538612 0.936736652 1 9.608926907 -3.804425375 0.416172062 1.006349238 0.15647989 0.715133367 0.072646928 2.403599873 0.214347275 0.017008502 1.096330373 0.000156883 3.804425375 -0.849869348 QGDTGDWIGTFLGHK ddPTM_HeLa_Curcumin_4h_R1 3 QGDTGDWIGTFLGHK 15 0 Q9Y3F4-2;Q9Y3F4 Q9Y3F4-2 STRAP Serine-threonine kinase receptor-associated protein 0 0 ;; ;; 179.81 4.83E-05 19519900 6094.72 5129.195 5340.324 4892.15 5948.41 8399.52 5706.7 5616.8 6510 5375.2 FALSE FALSE TRUE 5612.316481 5572.539761 5538.241105 4871.90758 5877.479096 6657.36487 5866.814643 7329.336463 5795.869287 5561.9878 1.009048686 1.001897156 0.995730538 0.87592921 1.056722759 1.196939855 1.054805378 1.317754862 1.042049982 1 12.44138486 -2.304858993 0.626883599 0.997105363 4.768020685 0.653070427 0.067900386 13.64284203 0.498610314 0.011190401 62.19505994 0.004956111 2.304858993 3.770915322 QGEAEFNR ddPTM_HeLa_Curcumin_4h_R1 1 QGEAEFNR 8 0 O43707;O43707-2;F5GXS2;O43707-3 O43707 ACTN4 Alpha-actinin-4 0 0 107.57 0.0034992 0 1507.9 947.66 1565.2 1162.9 1692.8 1633 1393.8 1626.9 829.05 933.67 FALSE FALSE TRUE 1388.548124 1029.571508 1623.207689 1158.088228 1672.614466 1294.297392 1432.906277 2122.934321 738.1052892 966.114963 1.437249372 1.065682188 1.68013927 1.19870644 1.731278916 1.339692937 1.483163321 2.197393066 0.763993228 1 9.916051063 -1 0.116549708 0.873596701 3.793424637 0.551341174 0.263856149 61.53350848 0.496519501 1.155782712 29.18827654 0.1 1 2.919827936 QGGLGPMNIPLVSDPK ddPTM_HeLa_Curcumin_4h_R1 1 QGGLGPMNIPLVSDPK 16 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 0 154.47 1.65E-23 0 0 68.889 278.23 0 0 187.06 200.16 178.76 0 216.91 FALSE FALSE TRUE 0 74.8434582 288.5414486 0 0 148.2616474 205.7759509 233.2631011 0 224.4476064 0 0.333456255 1.285562601 0 0 0.660562391 0.916810628 1.039276403 0 1 7.8102349 -2.539320311 21.91316489 0.545365576 0.976859199 0 0.488300496 0 0 0.068717455 0 0.002888549 2.539320311 0.431493623 QGGLGPMNIPLVSDPKR ddPTM_HeLa_Curcumin_4h_R1 2 QGGLGPMNIPLVSDPKR 17 1 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 0 ; ; 130.95 7.94E-05 3253410 1286.48 1122.83 1098.14 1245.52 1288.41 1823.21 1201.42 1217.25 1521.15 1162.27 FALSE FALSE TRUE 1184.653751 1219.882422 1138.838034 1240.366368 1273.046552 1445.055694 1235.128612 1588.383921 1354.283651 1202.658796 0.985028966 1.01432129 0.946933609 1.031353508 1.058526788 1.201550846 1.026998361 1.320726982 1.126074707 1 10.23201168 -1 0.460103549 0.989877643 8.047623032 0.538289573 0.073542535 30.66136299 0.323807991 0.011507454 206.225719 0.1 1 7.057745389 QGGSASQSQPS(ph)PCDSK ddPTM_HeLa_Curcumin_4h_R1 2 QGGSASQSQPSPCDSK 16 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 0 QGGSASQSQPS(1)PCDSK;QGGSASQSQPS(0.999)PCDSK ; 250.1 5.67E-40 5124200 2836 1970.25 2652.3 2426.98 2127.76 3086.2 2082.51 1071.53 2588.5 2025.55 TRUE FALSE FALSE 2611.527607 2140.549631 2750.596571 2416.9378 2102.387852 2446.087331 2140.939626 1398.234564 2304.548026 2095.937712 1.245994856 1.021284945 1.312346524 1.153153448 1.003077448 1.167061081 1.021471017 0.667116468 1.09953078 1 11.03338013 -4.276287425 2.684689509 1.123034706 0.585305206 0.665476503 0.097354852 0.233618639 2.261881792 0.015815023 0.274458725 5.29E-05 4.276287425 -0.5377295 QGGSPDEPDS(ph)K ddPTM_HeLa_Curcumin_4h_R1 2 QGGSPDEPDSK 11 0 Q9ULX6;Q9ULX6-2;V9GZ50 Q9ULX6 AKAP8L A-kinase anchor protein 8-like 1 0 QGGS(0.012)PDEPDS(0.988)K;QGGS(0.237)PDEPDS(0.763)K ; 164.53 0.00027431 30737000 10850.1 14465.5 11598.1 9442.4 9577.9 8355.6 6092.1 4475.8 8027.1 10059.1 TRUE FALSE FALSE 9991.303136 15715.83336 12027.93579 9403.329851 9463.689798 6622.554373 6263.02793 5840.450816 7146.547213 10408.65298 0.959903569 1.509881576 1.155570833 0.903414675 0.909213692 0.6362547 0.601713588 0.561114952 0.686596741 1 13.34549576 -5.370829657 1.672049583 1.036689661 0.571783768 0.503992844 0.195339616 0.223511065 1.194486711 0.026717741 0.084179215 4.26E-06 5.370829657 -0.464905893 QGGSQPSSFS(ph)PGQSQVTPQDQEK ddPTM_HeLa_Curcumin_4h_R1 1 QGGSQPSSFSPGQSQVTPQDQEK 23 0 Q9H0L4 Q9H0L4 CSTF2T Cleavage stimulation factor subunit 2 tau variant 1 0 QGGSQPS(0.017)S(0.1)FS(0.878)PGQS(0.004)QVTPQDQEK 108.88 7.97E-06 5259200 1585 1515.4 1483.8 1468.7 1755.1 2100.9 1338.3 1502.5 1862 1438.7 TRUE FALSE FALSE 1459.545578 1646.384424 1538.790933 1462.622909 1734.171579 1665.149658 1375.849096 1960.605333 1657.743258 1488.694718 0.980419666 1.10592481 1.0336511 0.982486799 1.164894023 1.11852997 0.924198279 1.316996231 1.113554874 1 10.53983222 -1 0.390521784 0.998365812 4.127651591 0.202801906 0.097215994 51.695249 0.618966765 0.021336477 124.9383281 0.1 1 3.129285779 SES(ph)LSNCSIGKK ddPTM_HeLa_Curcumin_4h_R1 1 SESLSNCSIGKK 12 1 A0A3B3ISP1;Q92625 A0A3B3ISP1 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 0 S(0.028)ES(0.971)LS(0.001)NCSIGKK 83.292 0.010093 176610000 2574.4 2837 2438.3 2812.6 2601.4 2874.4 2069.1 502.8 3150.4 3091.6 TRUE FALSE FALSE 2370.633524 3082.217639 2528.665543 2800.962206 2570.380004 2278.217039 2127.153377 656.1014054 2804.809002 3199.03287 0.741046941 0.963484204 0.790446877 0.87556531 0.803486588 0.712158059 0.664936393 0.205093674 0.876767797 1 11.6434201 -4.285990108 1.177014877 0.871271981 1.38E-29 0.852579375 0.081295966 0.536143313 0.621127547 0.015717196 0.565002807 5.18E-05 4.285990108 -0.871271981 down QGMKCLECGVK ddPTM_HeLa_Curcumin_4h_R1 1 QGMKCLECGVK 11 1 A0A3B3ISZ1;Q8NB66 A0A3B3ISZ1 UNC13C Protein unc-13 homolog C 0 0 110.41 0.0035701 0 1437.3 1041.2 1124.5 1091.7 1305.7 1097.5 1088.6 935.21 893.45 1198.6 FALSE FALSE TRUE 1323.536188 1131.196689 1166.174959 1087.182835 1290.13038 869.8661286 1119.143186 1220.351224 795.4407703 1240.251261 1.067151657 0.912070581 0.94027315 0.876582729 1.040216947 0.701362826 0.902351984 0.983954834 0.641354535 1 10.27641671 -7.246968676 20.93055999 1.031710495 0.905047106 0 0.149241985 77.87927279 112644.4346 0.013601918 0.016591886 5.66E-08 7.246968676 -0.126663389 QGMS(ph)PTFSR ddPTM_HeLa_Curcumin_4h_R1 1 QGMSPTFSR 9 0 A0A0C4DGA7;O94929-2;O94929-3;O94929 A0A0C4DGA7 ABLIM3 Actin-binding LIM protein 3 1 0 QGMS(0.999)PT(0.001)FSR 126.12 0.0046508 43343000 2297.6 1744.4 1769.2 1808.4 1942.1 2228.6 1418.1 956.7 2118 1696.3 TRUE FALSE FALSE 2115.742536 1895.178163 1834.768108 1800.91732 1918.941726 1766.363239 1457.888069 1248.393426 1885.660699 1755.246299 1.205382138 1.079722068 1.045305214 1.026019722 1.093260659 1.00633355 0.830588887 0.71123547 1.074299772 1 10.77745777 -4.625912195 1.427877358 1.089983607 0.664263021 0.841361368 0.053003082 0.261578034 0.747278774 0.011699859 0.130721774 2.37E-05 4.625912195 -0.425720587 QGPGPGGPK(ac)GGK ddPTM_HeLa_Curcumin_4h_R1 2 QGPGPGGPKGGK 12 1 P23246;P23246-2 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 1 ; QGPGPGGPK(1)GGK;QGPGPGGPK(1)GGK 130.98 0.00041292 11260900 4119.2 3654.4 3306.5 3530.5 3428.1 4757.5 3694.2 6380.9 4398.5 3737 FALSE TRUE FALSE 3793.160973 3970.270052 3429.041799 3515.891726 3387.222146 3770.740872 3797.84931 8326.407036 3915.995555 3866.860472 0.98094074 1.026742517 0.886776708 0.90923677 0.875961823 0.975142729 0.98215318 2.153273204 1.012706712 1 11.91694699 -4.261418972 7.756486733 0.97127261 2.16436394 0.980217896 0.050793288 0.009661503 6.285533231 0.007517872 0.059978164 5.48E-05 4.261418972 1.19309133 QGPPS(ph)PCQQLVLTK ddPTM_HeLa_Curcumin_4h_R1 1 QGPPSPCQQLVLTK 14 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 0 QGPPS(0.984)PCQQLVLT(0.016)K 91.401 0.0090692 9864500 1710.2 1145.8 1128.6 1278.7 1227.8 1275.5 696.66 764.98 1476.2 1229 TRUE FALSE FALSE 1574.835865 1244.837846 1170.426909 1273.409078 1213.159287 1010.946922 716.2064046 998.2188805 1314.264553 1271.707659 1.238363121 0.978871078 0.920358465 1.001337902 0.953960825 0.794952295 0.563184785 0.784943673 1.033464369 1 10.31255135 -5.453483529 0.782195422 1.101258398 0.634600998 0.651957215 0.100910418 0.397046278 0.393411105 0.021437137 0.114052088 3.52E-06 5.453483529 -0.4666574 AEAPLPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 AEAPLPSPK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 AEAPLPS(1)PK 98.898 0.013776 332940000 8398.5 7098.8 7597.3 7816 8479.1 9226.6 10764 16477 8688.8 6664.5 TRUE FALSE FALSE 7733.749863 7712.38864 7878.862621 7783.659463 8377.99227 7312.899155 11066.00887 21500.76145 7735.660378 6896.090879 1.12146867 1.118371085 1.142511426 1.128706045 1.214890061 1.060441239 1.604678515 3.117818751 1.121745713 1 12.75156307 -4.241825746 2.106456567 1.083400312 3.749913098 0.988843008 0.063927591 0.059029577 0.274336599 0.010828763 0.302832676 5.73E-05 4.241825746 2.666512785 up QGPVS(ph)PGPAPPPSFIMSYK ddPTM_HeLa_Curcumin_4h_R1 1 QGPVSPGPAPPPSFIMSYK 19 0 P29375 P29375 KDM5A Lysine-specific demethylase 5A 1 0 QGPVS(1)PGPAPPPSFIMSYK 94.057 0.0027535 0 996.56 566.58 681.37 790.94 743.43 1036.6 760.36 674.44 908.02 907.23 TRUE FALSE FALSE 917.6812244 615.5526506 706.6221716 787.6672999 734.5650828 821.5974751 781.6936552 880.0736513 808.4124778 938.756175 0.977550134 0.655710894 0.752721729 0.839054188 0.782487618 0.875197945 0.832690826 0.937489068 0.861152767 1 9.874606682 -7.41537086 10.37273098 0.990112893 0.811880387 0.331244187 0.081511937 0.233948693 21.2375937 0.012120655 0.013846578 3.84E-08 7.41537086 -0.178232506 QGPVSQSATQQPVTADKQQGHEPVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 QGPVSQSATQQPVTADKQQGHEPVSPR 27 1 Q9BTA9-2;Q9BTA9;A0A0A0MRT2;Q9BTA9-5 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 0 QGPVSQSAT(0.003)QQPVT(0.01)ADKQQGHEPVS(0.987)PR;QGPVSQSAT(0.002)QQPVTADKQQGHEPVS(0.997)PR;QGPVSQSAT(0.003)QQPVT(0.054)ADKQQGHEPVS(0.943)PR ;; 110.43 2.52E-08 103929000 7504.5 5752.5 5870.04 6095.1 6142.6 8165.5 5827.84 5651.44 8023.5 6821.67 TRUE FALSE FALSE 6910.510906 6249.720467 6087.588846 6069.880091 6069.353507 6471.883256 5991.353506 7374.53804 7143.342124 7058.722525 0.979003054 0.885389735 0.86242076 0.859911984 0.859837384 0.916863247 0.848787225 1.044741172 1.011987948 1 12.7851914 -7.30866759 4.590814632 0.990759733 0.891454143 0.414193737 0.054257086 0.141623939 6.6495078 0.008693852 0.010021262 4.91E-08 7.30866759 -0.099305589 QGQDVAPPPNPVPQRT(ph)SPTGPK ddPTM_HeLa_Curcumin_4h_R1 1 QGQDVAPPPNPVPQRTSPTGPK 22 1 Q9UPY8-2 Q9UPY8-2 MAPRE3 Microtubule-associated protein RP/EB family member 3 1 0 QGQDVAPPPNPVPQRT(0.575)S(0.386)PT(0.04)GPK 74.3 0.0013756 8409000 6161.3 5159.6 4640.5 5409.3 4485.1 5618.6 4264 5167 6721.5 6436.6 TRUE FALSE FALSE 5673.626604 5605.572833 4812.481012 5386.91775 4431.618112 4453.239025 4383.636364 6742.394514 5984.168266 6660.271371 0.851861176 0.841643309 0.722565305 0.808813553 0.665381013 0.668627264 0.65817684 1.0123303 0.898487154 1 12.70136525 -7.942613381 0.55306396 0.990967259 0.740570791 0.318381873 0.104150503 0.476218086 0.342141383 0.047406762 0.031561328 1.14E-08 7.942613381 -0.250396468 QGQETAVAPSLVAPALNKPK ddPTM_HeLa_Curcumin_4h_R1 1 QGQETAVAPSLVAPALNKPK 20 1 Q15691 Q15691 MAPRE1 Microtubule-associated protein RP/EB family member 1 0 0 177.12 2.13E-07 4157300 2888.4 2115.9 2086 2315.3 2571.1 3037 2320.5 2407.1 2780.7 2472.1 FALSE FALSE TRUE 2659.780092 2298.788968 2163.308995 2305.719902 2540.441312 2407.091966 2385.606985 3141.013709 2475.664167 2558.005291 1.039786783 0.898664665 0.845701533 0.901374172 0.993133721 0.941003513 0.932604398 1.227915251 0.967810417 1 11.32080353 -4.254532375 24.6903362 0.980558095 1.227915387 0.608006396 0.062636828 463.5546873 1657009.603 0.010581727 0.140468239 5.57E-05 4.254532375 0.247357293 QGQSQAASSSSVT(ph)SPIK ddPTM_HeLa_Curcumin_4h_R1 1 QGQSQAASSSSVTSPIK 17 0 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 1 0 QGQS(0.001)QAAS(0.005)S(0.013)S(0.055)S(0.047)VT(0.752)S(0.126)PIK 70.917 0.009212 0 1312.7 1095.4 1172.5 1204 1032.7 1172.2 981.82 652.57 1367.9 1369.5 TRUE FALSE FALSE 1208.79841 1190.081495 1215.953881 1199.018167 1020.385727 929.0725066 1009.367227 851.5355889 1217.844792 1417.090023 0.853014551 0.839806558 0.858063963 0.846112913 0.720057096 0.655619962 0.712281655 0.600904371 0.859398325 1 10.4687157 -2.894559316 0.13970715 1.067182959 6.33E-12 0.780362799 0.052958284 9.055915095 0.139335359 0.128947213 1.812581274 0.001274796 2.894559316 -1.067182959 KS(ph)SLLSEEQQETSTLVETIR ddPTM_HeLa_Curcumin_4h_R1 1 KSSLLSEEQQETSTLVETIR 20 1 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;X6R5W5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 0 KS(0.443)S(0.443)LLS(0.114)EEQQETSTLVETIR 62.617 0.0061969 3279300 580.75 652.29 677.3 630.7 582.37 850.21 952.46 1573.1 631.77 755.9 TRUE FALSE FALSE 534.7830247 708.6710411 702.4013338 628.0903305 575.4256181 673.8668622 979.1834642 2052.730948 562.4664116 782.1674687 0.683719339 0.906034921 0.89801911 0.803012597 0.735680837 0.861537828 1.251884671 2.624413608 0.71911251 1 9.611333724 -4.241739342 2.238915222 0.843326916 3.137829758 0.970789357 0.093686749 0.098658248 0.539695349 0.017267759 0.454345661 5.73E-05 4.241739342 2.294502842 up QGS(ph)FSEDVISHK ddPTM_HeLa_Curcumin_4h_R1 3 QGSFSEDVISHK 12 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;E9PNZ4 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 1 0 QGS(0.976)FS(0.024)EDVISHK;QGS(0.95)FS(0.049)EDVIS(0.001)HK;QGS(0.96)FS(0.04)EDVISHK ;; 145.94 0.00038789 65904000 15407.2 12829.8 14918.8 15203.3 15761.3 17476.3 14330.3 13051.8 17363.8 14647.5 TRUE FALSE FALSE 14187.70386 13938.75074 15471.70385 15140.39277 15573.35679 13851.51838 14732.36965 17031.23374 15459.03458 15156.49953 0.936080513 0.919655011 1.020796643 0.998937303 1.027503531 0.913899568 0.972016633 1.123691767 1.019960747 1 13.88764897 -6.728431654 24.99931964 0.965210318 1.003767882 0.10508267 0.056102283 351.2423298 266022.4772 0.008715055 0.012324495 1.87E-07 6.728431654 0.038557564 QGS(ph)FTIEKPSPNIPIELIPHINK ddPTM_HeLa_Curcumin_4h_R1 2 QGSFTIEKPSPNIPIELIPHINK 23 1 H0Y2V6;Q5SW79;Q5SW79-3;Q5SW79-2 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 0 QGS(0.499)FT(0.499)IEKPS(0.001)PNIPIELIPHINK;QGS(0.459)FT(0.459)IEKPS(0.082)PNIPIELIPHINK ; 88.471 9.65E-05 652300000 9872.7 8080.7 9003.3 8963.8 8947.5 11520.6 9911.2 8060.4 11304 10282.2 TRUE FALSE FALSE 9091.265377 8779.159701 9336.970218 8926.710171 8840.806906 9131.097696 10189.2816 10517.97885 10063.97948 10639.50568 0.854481932 0.825147329 0.877575566 0.839015499 0.830941509 0.858225745 0.95768374 0.988577775 0.945906678 1 13.3771435 -9.255438084 0.985415849 1.000025261 0.875543369 0.312676847 0.053498709 0.429307751 0.747601671 0.037303853 0.010203162 5.55E-10 9.255438084 -0.124481892 QGS(ph)PDQVS(ph)PVSEMTSTSLYQDK ddPTM_HeLa_Curcumin_4h_R1 2 QGSPDQVSPVSEMTSTSLYQDK 22 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 QGS(1)PDQVS(1)PVSEMTSTSLYQDK;QGS(0.999)PDQVS(0.998)PVS(0.003)EMT(0.001)STSLYQDK ; 124.8 2.19E-05 17820000 6804.43 6217.58 6907.29 6423.97 7368.28 7538.4 6679.68 7226.24 6141.45 5225.66 TRUE FALSE FALSE 6265.852185 6754.99991 7163.280244 6397.389314 7280.418073 5974.850865 6867.093843 9429.48731 5467.7483 5407.251296 1.15878694 1.249248378 1.324754455 1.183113002 1.346417556 1.104970074 1.269978676 1.743859642 1.011188125 1 12.40067969 -1 0.148046239 0.959121175 2.860085656 0.558594262 0.134753751 40.44574713 0.388860564 0.304977313 16.53371759 0.1 1 1.900964481 QGS(ph)PGSVSK ddPTM_HeLa_Curcumin_4h_R1 2 QGSPGSVSK 9 0 O00425 O00425 IGF2BP3 Insulin-like growth factor 2 mRNA-binding protein 3 1 0 QGS(0.998)PGS(0.002)VSK;QGS(0.86)PGS(0.139)VS(0.001)K ; 107.39 0.009994 160903000 13410.5 35485 13539.8 12842.3 11397.6 8553.8 7885.4 5635.4 8685.9 12106.1 TRUE FALSE FALSE 12349.04477 38552.16528 14041.5969 12789.16197 11261.69106 6779.645459 8106.643102 7353.607518 7733.078501 12526.78607 0.985811101 3.077578323 1.120925736 1.020945188 0.899008812 0.541211881 0.647144691 0.587030662 0.617323426 1 13.6127287 -5.606544318 2.070689556 1.184438473 0.597503018 0.193695595 0.632975976 0.508436283 4.381814924 0.097417367 0.233927847 2.47E-06 5.606544318 -0.586935456 ST(ph)PAMMNGQGSTTSSSK ddPTM_HeLa_Curcumin_4h_R1 1 STPAMMNGQGSTTSSSK 17 0 Q6ZN18-2;Q6ZN18;F5GZR7;A0A669KBC9;A0A669KBL4;G5EA50;Q6ZN18-3 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 0 S(0.427)T(0.573)PAMMNGQGSTTSSSK 105.53 0.012677 4642800 807.7 789.82 761.07 722.17 661.94 689.62 567.72 110.66 818.32 628.89 TRUE FALSE FALSE 743.7696927 858.0885214 789.2759237 719.1818519 654.0467978 546.5850384 583.6486953 144.3997246 728.5523433 650.7438807 1.142953034 1.318627108 1.21288259 1.105168828 1.005075602 0.839938806 0.896894635 0.221899474 1.119568489 1 9.34594603 -4.285087332 1.222189828 1.096625303 1.21E-21 0.833275425 0.117810864 0.497368674 0.630416884 0.019224209 0.679927843 5.19E-05 4.285087332 -1.096625303 down QGS(ph)PVAAGAPAK ddPTM_HeLa_Curcumin_4h_R1 4 QGSPVAAGAPAK 12 0 Q9NZI8 Q9NZI8 IGF2BP1 Insulin-like growth factor 2 mRNA-binding protein 1 1 0 QGS(1)PVAAGAPAK;QGS(1)PVAAGAPAK;QGS(1)PVAAGAPAK;QGS(1)PVAAGAPAK ;;; 144.88 0.00089065 1718470000 35977.5 28114.3 30138.6 30933.2 29656.4 33102.4 31128.2 29954.7 34365 29954.7 TRUE FALSE FALSE 33129.84291 30544.37482 31255.56303 30805.20661 29302.7668 26236.5891 32001.57351 39087.75014 30595.24548 30995.6236 1.068855505 0.985441533 1.008386327 0.993856649 0.945384006 0.846461082 1.032454579 1.261073197 0.987082753 1 14.91977691 -7.233440602 24.0856311 1.032515113 1.001758265 0 0.100148056 1939.259364 1668228.004 0.016768617 0.020533565 5.84E-08 7.233440602 -0.030756848 QGSFT(ph)IEKPSPNIPIELIPHINK ddPTM_HeLa_Curcumin_4h_R1 1 QGSFTIEKPSPNIPIELIPHINK 23 1 H0Y2V6;Q5SW79;Q5SW79-3;Q5SW79-2 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 0 QGS(0.232)FT(0.767)IEKPS(0.002)PNIPIELIPHINK 65.887 0.0020307 155950000 3686.1 2858.7 2851.2 3249.5 3218.7 3813.5 2977 2948.9 3431.3 3402.2 TRUE FALSE FALSE 3394.341295 3105.79329 2956.86798 3236.05443 3180.319105 3022.537113 3060.526608 3848.006035 3054.894975 3520.426197 0.964184762 0.882220821 0.839917616 0.919222347 0.903390364 0.858571362 0.869362525 1.093051188 0.867762823 1 11.78153438 -7.446123818 3.390325485 0.985302953 0.903562674 0 0.076198615 0.254117305 5.42568797 0.01142979 0.012747074 3.58E-08 7.446123818 -0.08174028 VNPVTSLSENYT(ph)CSDSEESSEKDK ddPTM_HeLa_Curcumin_4h_R1 1 VNPVTSLSENYTCSDSEESSEKDK 24 1 Q14432 Q14432 PDE3A "cGMP-inhibited 3,5-cyclic phosphodiesterase A" 1 0 VNPVTSLS(0.002)ENY(0.043)T(0.559)CS(0.378)DS(0.017)EES(0.001)S(0.001)EKDK 85.013 0.00012954 19976000 1916.8 1495 1571.4 1455.5 1767.2 1585 1077.3 421.35 1787.2 1530.1 TRUE FALSE FALSE 1765.083257 1624.221138 1629.637466 1449.477527 1746.127294 1256.253133 1107.526139 549.8176753 1591.148631 1583.270861 1.114833413 1.025864354 1.029285327 0.915495612 1.102860753 0.793454338 0.699517793 0.34726697 1.00497563 1 10.62869237 -4.285046717 0.923201166 1.0489066 2.36E-20 0.913129225 0.065778123 0.396488824 0.2577922 0.010492405 0.413037911 5.19E-05 4.285046717 -1.0489066 down QGSIT(ph)SPQANEQSVT(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 1 QGSITSPQANEQSVTPQR 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 QGS(0.045)IT(0.795)S(0.158)PQANEQS(0.054)VT(0.947)PQR 95.429 0.0074169 7452600 1576.8 1877 1992.3 1797.2 2703.9 2034 2159.1 1299 1602.8 1528.1 TRUE FALSE FALSE 1451.994616 2039.239516 2066.136391 1789.763663 2671.657758 1612.125472 2219.678535 1695.05912 1426.97685 1581.201361 0.918285711 1.289677309 1.306687713 1.131901165 1.689637907 1.019557352 1.403792451 1.072007122 0.902463712 1 10.62680539 -7.257643163 24.39508136 0.961412693 1.280436922 0.416633294 0.179951226 154.3741282 992032.7965 0.027047451 0.032454686 5.53E-08 7.257643163 0.319024229 QGSIT(ph)SPQANEQSVT(ph)PQRR ddPTM_HeLa_Curcumin_4h_R1 1 QGSITSPQANEQSVTPQRR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 QGS(0.044)IT(0.819)S(0.137)PQANEQS(0.346)VT(0.654)PQRR 73.058 0.0020914 0 1677.4 1704 1645.5 1484.3 1296.8 1963.6 1707.7 1185.5 1435.2 1523.7 TRUE FALSE FALSE 1544.63202 1851.286167 1706.483678 1478.15836 1281.336507 1556.327226 1755.613466 1546.953493 1277.762151 1576.648462 0.979693354 1.174190831 1.082348868 0.937531984 0.812696386 0.987111118 1.11350977 0.981165764 0.810429326 1 10.62264531 -6.21640951 24.98746765 1.013143035 0.967186805 0.036430666 0.109480508 1210.370831 671645.9533 0.014593756 0.024200963 6.08E-07 6.21640951 -0.04595623 QGSIT(ph)SPQANEQSVTPQR ddPTM_HeLa_Curcumin_4h_R1 1 QGSITSPQANEQSVTPQR 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 QGS(0.045)IT(0.793)S(0.144)PQANEQS(0.009)VT(0.009)PQR 86.772 0.011613 11329000 2790.7 2483.2 2902 2845.5 3858.3 3089.4 2481.8 2547.1 2192.9 2564.2 TRUE FALSE FALSE 2569.81315 2697.836743 3009.550673 2833.726075 3812.292292 2448.623615 2551.432629 3323.699065 1952.344356 2653.305759 0.968532609 1.016783209 1.134264554 1.067998313 1.436808509 0.922857687 0.961605205 1.252663419 0.735815821 1 11.37357522 -6.850528984 3.941916248 0.98541475 1.123856436 0.252432149 0.157315196 0.283357638 8.414206114 0.021525905 0.028903606 1.41E-07 6.850528984 0.138441686 QGSITSPQANEQSVT(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 2 QGSITSPQANEQSVTPQR 18 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 QGSITSPQANEQSVT(1)PQR;QGSITSPQANEQSVT(1)PQR ; 237.14 1.32E-24 16859700 3191.34 3341.52 3596.9 3100.1 4031.07 3779.55 3398.68 2514.52 2937.39 2506.33 TRUE FALSE FALSE 2938.742072 3630.346099 3730.204278 3087.272608 3983.002123 2995.628726 3494.037814 3281.185573 2615.165666 2593.424781 1.133151072 1.399827026 1.438331393 1.190423038 1.535807845 1.155086027 1.347267844 1.265194039 1.008383079 1 11.34064281 -7.490661863 2.587341726 1.051454434 1.332717799 0.587078844 0.110614069 0.136966941 1.806112166 0.019597073 0.021440851 3.23E-08 7.490661863 0.281263365 QGSITSPQANEQSVT(ph)PQRR ddPTM_HeLa_Curcumin_4h_R1 3 QGSITSPQANEQSVTPQRR 19 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 QGSITSPQANEQS(0.006)VT(0.994)PQRR;QGSITSPQANEQS(0.003)VT(0.997)PQRR;QGSITSPQANEQSVT(1)PQRR ;; 218.79 1.23E-22 90603200 4595.9 4496.3 4579.7 4413 5655.3 5693.4 4679.02 3569.79 4958.8 4290.2 TRUE FALSE FALSE 4232.129665 4884.940137 4749.427711 4394.740175 5587.864241 4512.524662 4810.300708 4658.202538 4414.832046 4439.284131 0.953336065 1.10038916 1.069863422 0.98996596 1.25873093 1.016498275 1.083575767 1.049313899 0.994491886 1 12.11611133 -7.259454343 24.99394091 0.977964252 1.081678717 0.30246128 0.068493252 143.924523 1812187.314 0.010888988 0.012983275 5.50E-08 7.259454343 0.103714464 QGSPDQVS(ph)PVS(ph)EMTSTSLYQDKQEGK ddPTM_HeLa_Curcumin_4h_R1 1 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 QGS(0.112)PDQVS(0.828)PVS(0.503)EMT(0.547)S(0.009)T(0.001)SLYQDKQEGK 127.9 6.18E-08 113510000 3825 2754.7 2941.3 3437.9 2909.6 3615.5 2919.2 3595.4 3906.9 3132.7 TRUE FALSE FALSE 3522.247214 2992.803993 3050.307165 3423.674881 2874.90492 2865.604545 3001.104895 4691.620909 3478.322845 3241.561092 1.086589799 0.923260092 0.940999438 1.056180891 0.886889014 0.88401991 0.925820865 1.447333793 1.073039423 1 11.66247305 -4.255391943 24.69333537 1.001691271 1.447334027 0.770460829 0.076083959 242.3487805 989542.7249 0.011932048 0.145748695 5.55E-05 4.255391943 0.445642756 QGSPDQVS(ph)PVSEMT(ph)STSLYQDKQEGK ddPTM_HeLa_Curcumin_4h_R1 1 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 QGS(0.004)PDQVS(0.62)PVS(0.468)EMT(0.547)S(0.153)T(0.153)S(0.053)LY(0.001)QDKQEGK 99.923 4.07E-06 23689000 2240.6 2010.9 2169 2098 1766.3 2871.8 2065.8 2218.8 2675.8 2384.9 TRUE FALSE FALSE 2063.254146 2184.713236 2249.385048 2089.319032 1745.238026 2276.156308 2123.760788 2895.301906 2382.271435 2467.775097 0.83607868 0.885296735 0.911503261 0.846640779 0.707211134 0.922351599 0.860597382 1.17324383 0.965351922 1 11.2689952 -4.256920936 24.19516036 0.895387038 1.173244009 0.557270577 0.077098488 205.1840351 1098644.975 0.012387506 0.13055109 5.53E-05 4.256920936 0.27785697 ANS(ph)TSDSVFTETPS(ph)PVLK ddPTM_HeLa_Curcumin_4h_R1 1 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 2 0 ANS(0.885)T(0.081)S(0.023)DS(0.011)VFTETPS(1)PVLK 115.87 0.00098892 2656500 1857.9 1281.1 1693 1814.5 1672.3 2873.8 4091.1 14751 1835.1 2114.5 TRUE FALSE FALSE 1710.845255 1391.832576 1755.744069 1806.99208 1652.358915 2277.741486 4205.885255 19248.51199 1633.794121 2187.978718 0.781929569 0.636127109 0.80245025 0.825872786 0.755198806 1.04102543 1.922269728 8.797394527 0.7467139 1 11.09538299 -4.24160335 2.916725973 0.866094229 10.37792999 0.997147685 0.12715246 0.019495679 0.225022573 0.0225567 0.443746954 5.73E-05 4.24160335 9.51183576 up GGET(ph)PGSEQWK ddPTM_HeLa_Curcumin_4h_R1 2 GGETPGSEQWK 11 0 O60271-3;O60271;A0A087X2D8;O60271-5;O60271-9;O60271-4;O60271-2;D6RHI8 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 GGET(1)PGSEQWK;GGET(1)PGSEQWK ; 161.87 0.00091851 53094000 6430.8 6314 6465.1 6409.8 6853.3 8719.4 7995.7 20774 6636.5 4935.3 TRUE FALSE FALSE 5921.795394 6859.754025 6704.702293 6383.277946 6771.578874 6910.898152 8220.037823 27107.89697 5908.492554 5106.801308 1.159589935 1.343258453 1.312896643 1.249956198 1.325992234 1.353273358 1.609625542 5.308194961 1.156985008 1 12.31820421 -4.241214737 3.123771183 1.161290489 6.048265977 0.989152642 0.12687863 0.036014945 0.510711307 0.024099182 0.440475273 5.74E-05 4.241214737 4.886975488 up QGSPDQVSPVSEMT(ph)S(ph)TSLYQDKQEGK ddPTM_HeLa_Curcumin_4h_R1 1 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 QGS(0.092)PDQVS(0.088)PVS(0.284)EMT(0.598)S(0.434)T(0.433)S(0.031)LY(0.041)QDKQEGK 58.92 0.0058742 15654000 2382.4 1556.8 2041.2 2191.8 2095.6 2863.7 2043.8 2732.7 2921.2 2515.1 TRUE FALSE FALSE 2193.830526 1691.362855 2116.848668 2182.730912 2070.611339 2269.736339 2101.143527 3565.88765 2600.751668 2602.499538 0.842970573 0.649899387 0.813390603 0.838705591 0.795624095 0.872137077 0.807355966 1.370178015 0.999328388 1 11.34568219 -4.256629166 24.6433971 0.874576085 1.370178264 0.708603512 0.099277946 206.8612478 1059734.194 0.015853231 0.172714661 5.54E-05 4.256629166 0.49560218 QGSPDQVSPVSEMT(ph)STSLYQDKQEGK ddPTM_HeLa_Curcumin_4h_R1 4 QGSPDQVSPVSEMTSTSLYQDKQEGK 26 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 QGSPDQVS(0.014)PVS(0.116)EMT(0.612)S(0.193)T(0.061)S(0.004)LYQDKQEGK;QGSPDQVS(0.14)PVS(0.01)EMT(0.803)S(0.046)T(0.001)SLYQDKQEGK;QGSPDQVS(0.021)PVS(0.021)EMT(0.951)S(0.007)TSLYQDKQEGK;QGSPDQVS(0.326)PVS(0.092)EMT(0.548)S(0.026)T(0.007)SLYQDKQEGK ;;; 149 1.11E-08 178855000 10844.9 8125 9003.7 9277.7 8363.2 11629.1 10108.7 11106.8 11545.2 10392.4 TRUE FALSE FALSE 9986.514722 8827.288796 9337.385042 9239.311336 8263.474302 9217.093573 10392.32292 14493.21219 10278.72044 10753.53513 0.928672721 0.8208732 0.868308415 0.859188279 0.768442582 0.85712219 0.96640991 1.347762575 0.955845712 1 13.39252339 -4.267834942 4.040800351 0.920331773 1.382742225 0.780329803 0.071547677 0.102227278 3.522958757 0.012522391 0.136335811 5.40E-05 4.267834942 0.462410452 QGVGK(ac)YINPAATK ddPTM_HeLa_Curcumin_4h_R1 2 QGVGKYINPAATK 13 1 Q13356 Q13356 PPIL2 Peptidyl-prolyl cis-trans isomerase-like 2 0 1 ; QGVGK(1)YINPAATK;QGVGK(1)YINPAATK 210.79 3.99E-20 20470800 6679.6 6904.1 7957.9 5381.3 6197.8 7435.4 4746.4 3689.2 5354.2 4714 FALSE TRUE FALSE 6150.902612 7500.85964 8252.826774 5359.033606 6123.895283 5893.214226 4879.57121 4814.020097 4766.857656 4877.811149 1.260996464 1.537751137 1.691911909 1.09865541 1.255459692 1.208167771 1.00036083 0.986922197 0.977253426 1 12.25201819 -4.756088223 7.12044848 1.208300388 0.991977303 0.167443126 0.213603946 0.218853971 60.19020678 0.033292805 0.11474914 1.75E-05 4.756088223 -0.216323085 QGVGK(ac)YINPAATKR ddPTM_HeLa_Curcumin_4h_R1 1 QGVGKYINPAATKR 14 2 Q13356 Q13356 PPIL2 Peptidyl-prolyl cis-trans isomerase-like 2 0 1 QGVGK(1)YINPAATKR 113.37 0.00021192 9815600 3145.7 2957.3 2936.5 2559.9 2611.4 3616.7 2374.7 2128.1 3272.3 2869.6 FALSE TRUE FALSE 2896.714526 3212.915835 3045.329273 2549.307812 2580.260761 2866.555651 2441.327691 2776.947893 2913.336877 2969.318386 0.975548644 1.082038171 1.025598766 0.858549835 0.868974096 0.96539181 0.822184546 0.935213922 0.98114668 1 11.53591608 -6.262817607 24.99991214 0.999200559 0.88930517 0.623441515 0.047123397 68.6378925 1245034.58 0.007066177 0.011169703 5.46E-07 6.262817607 -0.10989539 QGVLTHGR ddPTM_HeLa_Curcumin_4h_R1 2 QGVLTHGR 8 0 P62753;A2A3R5 P62753 RPS6 40S ribosomal protein S6 0 0 ; ; 96.668 0.013572 5249100 6927.7 7527.7 6061.9 4800.2 5167 7598.9 4883.7 5206.8 5421.2 6861.1 FALSE FALSE TRUE 6379.365235 8178.360845 6286.559347 4780.338044 5105.3869 6022.802483 5020.723478 6794.329351 4826.507923 7099.522714 0.89856255 1.151959248 0.88549042 0.673332312 0.719116919 0.848339068 0.707191692 0.957012129 0.679835549 1 12.79350632 -6.518246018 24.98777772 0.968272699 0.777422328 0.208255416 0.133884704 132.1662596 712872.5328 0.015116487 0.021704385 3.03E-07 6.518246018 -0.190850371 QHDYS(ph)DYEDSSLEFLER ddPTM_HeLa_Curcumin_4h_R1 2 QHDYSDYEDSSLEFLER 17 0 A8MW92;A0A0A0MQS0;F8W9L8 A8MW92 PHF20L1 PHD finger protein 20-like protein 1 1 0 QHDYS(1)DYEDSSLEFLER;QHDY(0.02)S(0.979)DY(0.001)EDSSLEFLER ; 144.3 0.00013983 5686100 2077.68 1707.42 1913.33 1790.66 2023.31 2390.8 1739.11 971.91 2430.5 1823.78 TRUE FALSE FALSE 1913.229436 1855.001777 1984.239693 1783.250723 1999.18335 1894.92113 1787.904746 1268.240885 2163.880231 1887.156219 1.013816141 0.98296143 1.051444323 0.944940702 1.059362934 1.004114609 0.947406859 0.672038103 1.146635455 1 10.88199814 -4.245016566 2.603537857 1.007304605 0.594520487 0.792588944 0.053574659 0.08907012 0.744871975 0.003722507 0.081400161 5.69E-05 4.245016566 -0.412784118 QHEVEIPS(ph)PTQKEK ddPTM_HeLa_Curcumin_4h_R1 2 QHEVEIPSPTQKEK 14 1 A0A1B0GW84;A0A087WSZ7;Q08499-2;Q08499-10;Q08499-9;Q08499-11;Q08499;D6RHE0;Q08499-5;Q08499-4;Q08499-3;Q08499-6;Q08499-8 A0A1B0GW84;Q08499-6;Q08499-8 PDE4D "cAMP-specific 3,5-cyclic phosphodiesterase 4D" 1 0 QHEVEIPS(0.991)PT(0.009)QKEK;QHEVEIPS(0.999)PT(0.001)QKEK ; 86.8 0.0056373 14402100 4746.6 4399.3 4697.1 4463.4 4796.4 5327.5 4243.5 3543.5 4900.8 4908 TRUE FALSE FALSE 4370.901601 4779.555889 4871.178658 4444.931633 4739.206063 4222.516447 4362.561189 4623.896838 4363.194501 5078.552635 0.860658915 0.941125599 0.959166717 0.875235909 0.933180456 0.831440914 0.859016634 0.91047532 0.859141337 1 12.31020168 -9.439355226 0.99984677 1.004404061 0.893644693 0 0.05801687 0.406076516 0.677826603 0.034110324 0.007260723 3.64E-10 9.439355226 -0.110759367 QHGEQLGGGGS(ph)GGGGYNNSK ddPTM_HeLa_Curcumin_4h_R1 1 QHGEQLGGGGSGGGGYNNSK 20 0 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;H0YEH2;E9PR38;Q14671-4;E9PMX1 Q5T1Z4 PUM1 Pumilio homolog 1 1 0 QHGEQLGGGGS(1)GGGGYNNSK 106.5 0.00015109 4927700 1589.3 1447.6 1526.2 1497.2 1777.5 2562.4 1825.5 1043.5 1962.8 1671.5 TRUE FALSE FALSE 1463.505228 1572.724094 1582.762315 1491.004983 1756.304473 2030.929356 1876.718617 1361.658346 1747.485751 1729.584501 0.846160004 0.909307463 0.915111296 0.862059635 1.015448781 1.174229623 1.085069053 0.787274832 1.010350029 1 10.75620978 -5.643897524 7.007447991 0.919198212 1.034000658 0.15078448 0.103324044 0.2704179 15.5705016 0.015281125 0.030680303 2.27E-06 5.643897524 0.114802446 QHHSALECLLQR ddPTM_HeLa_Curcumin_4h_R1 2 QHHSALECLLQR 12 0 Q8TC59-2;Q8TC59 Q8TC59-2 PIWIL2 Piwi-like protein 2 0 0 ; ; 113.93 0.0020765 26117000 8219.1 12542.3 12174.9 12627.9 9148.4 592.25 3552.3 2688.9 9851.1 14676.7 FALSE FALSE TRUE 7568.549562 13626.40052 12626.1125 12575.6491 9039.311305 469.410674 3651.967977 3508.733232 8770.458976 15186.71423 0.498366496 0.897257979 0.831391986 0.82806912 0.595211786 0.030909298 0.240471238 0.231039656 0.577508659 1 13.89052214 -5.431676494 4.049530344 0.777139504 0.178067047 0.768615162 0.148008545 0.106268293 3.129855746 0.028190619 0.064996448 3.70E-06 5.431676494 -0.599072457 QHYIDLK ddPTM_HeLa_Curcumin_4h_R1 2 QHYIDLK 7 0 Q32Q12;P22392-2;J3KPD9;P22392;F6XY72;O60361 Q32Q12 NME1-NME2;NME2;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase 0 0 ; ; 104.44 0.014023 132289000 23982 19069 20554.7 20775.9 21083.5 27582 21503 20872.1 22867.9 20583.4 FALSE FALSE TRUE 22083.79939 20717.23939 21316.47526 20689.93483 20832.09303 21861.18229 22106.31631 27235.90721 20359.34858 21298.67162 1.036862758 0.97270101 1.000835904 0.971419026 0.978093536 1.026410599 1.037919956 1.27876084 0.955897577 1 14.37847583 -4.233561153 2.96568379 1.007971078 1.334416756 0.904286353 0.027408472 0.09392027 1.117064521 0.0036352 0.074795155 5.84E-05 4.233561153 0.326445678 QHYLS(ph)SEDEPDDNPDVLDSR ddPTM_HeLa_Curcumin_4h_R1 1 QHYLSSEDEPDDNPDVLDSR 20 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 QHYLS(0.5)S(0.5)EDEPDDNPDVLDSR 101.86 0.00021281 6851300 1273 1213.7 1123.7 1200.6 1153.5 1482.3 1236.8 1162.8 1466.9 1321.3 TRUE FALSE FALSE 1172.240707 1318.60682 1165.345311 1195.632235 1139.745266 1174.854271 1271.501279 1517.332367 1305.98474 1367.215077 0.857393052 0.964447249 0.852349663 0.874501939 0.833625437 0.859304649 0.929993606 1.109797861 0.955215286 1 10.4170245 -4.268436621 4.598524666 0.912169185 1.121138844 0.564848998 0.054122408 0.135328977 7.497809841 0.009471852 0.090000792 5.39E-05 4.268436621 0.208969659 QIAEEDFYEK ddPTM_HeLa_Curcumin_4h_R1 1 QIAEEDFYEK 10 0 P33993;P33993-3 P33993 MCM7 DNA replication licensing factor MCM7 0 0 154.24 0.0055187 2852900 1569.5 1320.9 1549 1568.5 1725 1980 1566.6 1277 1778.6 1390.7 FALSE FALSE TRUE 1445.272419 1435.07271 1606.407303 1562.009963 1704.430502 1569.325681 1610.55458 1666.351421 1583.49203 1439.026721 1.004340223 0.997252302 1.116315131 1.085462792 1.184432837 1.090546588 1.119197132 1.157971146 1.100390984 1 10.49087767 -6.74212825 5.994284779 1.001617116 1.12520293 0.558720715 0.041514998 0.045140926 5.308164597 0.004045872 0.005623282 1.81E-07 6.74212825 0.123585814 QIASNS(ph)PGSSPK ddPTM_HeLa_Curcumin_4h_R1 2 QIASNSPGSSPK 12 0 Q9C0D5-2;Q9C0D5 Q9C0D5-2 TANC1 Protein TANC1 1 0 QIAS(0.137)NS(0.788)PGS(0.068)S(0.006)PK;QIAS(0.015)NS(0.984)PGS(0.001)SPK ; 174.24 5.67E-14 6964300 9160.4 6843.9 7700.9 7433.8 7716.8 8993.7 5963.4 3740.1 8952.3 6996.3 TRUE FALSE FALSE 8435.344674 7435.45622 7986.302128 7403.040905 7624.7822 7128.30524 6130.716954 4880.439273 7970.255088 7239.420904 1.165196054 1.027078867 1.103168642 1.022601255 1.053230956 0.984651305 0.846851846 0.674147744 1.100952023 1 12.82165858 -4.277465424 0.977091058 1.07562807 0.457476374 0.892291764 0.044277974 0.591224594 0.435215749 0.009629768 0.381636808 5.28E-05 4.277465424 -0.618151696 QIATLHAQVADMK ddPTM_HeLa_Curcumin_4h_R1 2 QIATLHAQVADMK 13 0 P35579 P35579 MYH9 Myosin-9 0 0 ; ; 98.942 0.0025453 6392700 9841 7719 8680 8855.2 8731.1 10999 8325.9 7465.2 9421.9 8240.7 FALSE FALSE TRUE 9062.074466 8386.195965 9001.688436 8818.559529 8626.987335 8717.683416 8559.502346 9741.305114 8388.341142 8527.063712 1.062742671 0.983479923 1.05566098 1.034184782 1.011718409 1.022354671 1.003804197 1.142398538 0.983731496 1 13.05783332 -4.254615792 24.80805907 1.026172929 1.142398597 0.646559796 0.027025811 373.7891723 1358920.799 0.00377452 0.050374466 5.56E-05 4.254615792 0.116225669 QIATLHAQVADMKK ddPTM_HeLa_Curcumin_4h_R1 1 QIATLHAQVADMKK 14 1 P35579 P35579 MYH9 Myosin-9 0 0 92.792 0.0012462 1497800 4374.4 3748.3 3740.3 4153.8 3607.7 4601.2 3224.3 3140.6 4344.3 3968 FALSE FALSE TRUE 4028.161624 4072.28635 3878.918808 4136.612676 3564.680534 3646.859254 3314.76518 4098.154482 3867.741159 4105.887705 0.981069604 0.9918163 0.944721114 1.00748315 0.868187537 0.888202385 0.80731998 0.998116553 0.941998768 1 12.00347846 -5.760356017 24.99999887 0.988080252 0.884357255 0.425104252 0.048720992 15.36438798 354537.1322 0.006097806 0.011665499 1.74E-06 5.760356017 -0.103722998 QICLVMLETLSQS(ph)PQGR ddPTM_HeLa_Curcumin_4h_R1 4 QICLVMLETLSQSPQGR 17 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 0 QICLVMLETLS(0.081)QS(0.919)PQGR;QICLVMLETLS(0.009)QS(0.991)PQGR;QICLVMLET(0.024)LS(0.007)QS(0.969)PQGR;QICLVMLET(0.1)LS(0.206)QS(0.694)PQGR ;;; 211.26 2.34E-11 1048429000 12438.7 10059.2 10535.3 10495.7 10829.4 15791.5 10535.9 8145.3 12483.5 10722.1 TRUE FALSE FALSE 11454.16377 10928.67243 10925.74749 10452.27157 10700.26648 12516.16489 10831.509 10628.76447 11114.09128 11094.69218 1.032400321 0.98503611 0.984772476 0.942096582 0.964449153 1.128121871 0.97627846 0.95800445 1.001748503 1 13.43758202 -7.245312068 23.83341042 1.015300153 0.992769071 0.031820274 0.048994409 1262.483784 1865732.999 0.008311716 0.010156708 5.68E-08 7.245312068 -0.022531082 QICVVMLETLSQS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 3 QICVVMLETLSQSPPK 16 0 Q15366;Q15366-2;Q15366-5;H3BRU6;F8VZX2;Q15366-8 Q15366 PCBP2 Poly(rC)-binding protein 2 1 0 QICVVMLETLS(0.008)QS(0.992)PPK;QICVVMLETLS(0.459)QS(0.541)PPK;QICVVMLETLS(0.33)QS(0.67)PPK ;; 231.91 5.50E-22 165318900 6015.95 5553.6 5830.8 4225.79 6066.4 17801.2 9559.6 5684.77 5940.4 5396.08 TRUE FALSE FALSE 5539.781209 6033.628438 6046.894577 4208.304801 5994.062142 14109.03046 9827.816648 7418.030204 5288.752982 5583.593378 0.99215341 1.08059954 1.082975455 0.75369113 1.07351337 2.52687284 1.760123989 1.328540547 0.947195224 1 12.44697817 -5.404594737 8.558753065 0.992152722 1.858871067 0.668478244 0.285073548 0.129791909 8.712709901 0.038066995 0.085264271 3.94E-06 5.404594737 0.866718345 QIDIMVAHKK ddPTM_HeLa_Curcumin_4h_R1 1 QIDIMVAHKK 10 1 D6R9Q4;A0A3B3IT05;D6RAY6;Q96MT8-4;Q96MT8-3;Q96MT8-2;Q96MT8 D6R9Q4 CEP63 Centrosomal protein of 63 kDa 0 0 82.426 0.012106 4480200 1737 1092.1 1293 1217.4 1393.8 2243.4 1579.9 632.28 1141.2 1003.1 FALSE FALSE TRUE 1599.514617 1186.496258 1340.919717 1212.362721 1377.179845 1778.093552 1624.227742 825.0592613 1016.013215 1037.95765 1.541021078 1.143106616 1.291882879 1.168027155 1.32681699 1.71306946 1.564830455 0.794887211 0.978858063 1 10.01953187 -9.553835697 1.311877488 0.999242879 1.354816383 0.208631562 0.246392131 0.549320745 1.687983296 0.173709747 0.04067719 2.79E-10 9.553835697 0.355573505 QIDNPDYK ddPTM_HeLa_Curcumin_4h_R1 3 QIDNPDYK 8 0 P27797;K7EJB9;K7EL50 P27797 CALR Calreticulin 0 0 ;; ;; 152.34 0.00031942 33972700 18713.2 15074.7 17683.3 16082.1 18862.6 23450.2 17847.5 15886.6 17372.8 15465 FALSE FALSE TRUE 17232.03047 16377.6899 18338.65865 16015.55653 18637.67581 18586.36418 18348.25282 20730.35121 15467.0473 16002.4076 1.076839867 1.023451615 1.145993723 1.000821685 1.164679483 1.161472989 1.146593267 1.295452017 0.966545016 1 13.96600136 -1 0.260306736 1.018223759 2.677548968 0.721617913 0.051279567 17.97414086 0.22641041 0.022942319 13.40225468 0.1 1 1.659325209 QIDS(ph)S(ph)EEDDDEEDYDNDKR ddPTM_HeLa_Curcumin_4h_R1 1 QIDSSEEDDDEEDYDNDKR 19 1 O14646-2;O14646 O14646-2 CHD1 Chromodomain-helicase-DNA-binding protein 1 2 0 QIDS(0.933)S(0.982)EEDDDEEDY(0.085)DNDKR 78.419 0.0017151 0 2569.3 2358.6 1989 2106.2 2380.5 2516.8 2105.1 1355.8 2430.1 2167.1 TRUE FALSE FALSE 2365.937194 2562.466874 2062.71409 2097.485102 2352.114092 1994.78731 2164.16344 1769.177179 2163.52411 2242.406564 1.055088418 1.142730723 0.919866238 0.935372352 1.048924013 0.889574327 0.965107521 0.78896361 0.964822412 1 11.13083216 -2.816307138 0.49666183 1.028563358 2.54E-13 0.460126538 0.068612537 9.171634641 0.511423376 0.01306223 7.620685646 0.001526486 2.816307138 -1.028563358 TICTFDSSGFESMS(ph)PIKETVSSR ddPTM_HeLa_Curcumin_4h_R1 3 TICTFDSSGFESMSPIKETVSSR 23 1 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 0 TICTFDS(0.008)S(0.008)GFES(0.404)MS(0.574)PIKET(0.005)VSSR;TICT(0.001)FDS(0.049)S(0.041)GFES(0.026)MS(0.86)PIKET(0.019)VS(0.002)S(0.001)R;TICTFDS(0.059)S(0.05)GFES(0.218)MS(0.671)PIKET(0.001)VSSR ;; 121.97 2.24E-06 208357000 5242.7 3928 4718.6 4903.5 4659.6 6479.8 4030.7 1451.33 5705.8 4994 TRUE FALSE FALSE 4827.734763 4267.518817 4893.475467 4883.210616 4604.037313 5135.816438 4143.790594 1893.833836 5079.888015 5167.541128 0.934242156 0.825831611 0.94696401 0.944977601 0.890953202 0.993860776 0.801888266 0.366486456 0.983037752 1 12.33526225 -4.284137251 2.48938782 0.950598011 0.25362276 0.919384875 0.050888294 0.099281091 0.78797987 0.007794248 0.142998875 5.20E-05 4.284137251 -0.696975251 down LCPSCPAS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 LCPSCPASSPK 11 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 LCPSCPAS(0.5)S(0.5)PK 161.99 0.0003146 42744000 7370.6 6389.2 6317.7 6480.2 6423.4 6884.5 4327.1 1450.1 7333.2 5708.6 TRUE FALSE FALSE 6787.209233 6941.453978 6551.83952 6453.386649 6346.80515 5456.577096 4448.50678 1892.228815 6528.766307 5906.973425 1.149016382 1.175128696 1.109170306 1.092503078 1.074459743 0.92375176 0.753094091 0.320338129 1.105264208 1 12.52820341 -4.283461653 1.206552102 1.08596222 1.18E-15 0.960890695 0.048837497 0.270946736 0.332132798 0.010149506 0.363396429 5.21E-05 4.283461653 -1.08596222 down QIEEELWEEEFIER ddPTM_HeLa_Curcumin_4h_R1 2 QIEEELWEEEFIER 14 0 D6RA77;Q9BPZ3 D6RA77 PAIP2 Polyadenylate-binding protein-interacting protein 2 0 0 ; ; 155.98 0.0032561 3489600 2281.71 1427.69 1776.57 1783.72 1631.89 2346.75 1963.47 1650.13 2051.5 1828.3 FALSE FALSE TRUE 2101.110246 1551.093162 1842.411247 1776.339439 1612.430778 1860.007597 2018.559684 2153.247041 1826.455583 1891.833289 1.110621247 0.819888925 0.973876112 0.93895136 0.852311241 0.983177327 1.066986027 1.13818012 0.965442142 1 10.88556925 -10.32054599 6.257886459 0.999154027 1.016132888 0 0.10088787 1.759114955 178.1678381 0.111454905 0.0156178 4.78E-11 10.32054599 0.016978861 NVMILTNPVAAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 4 NVMILTNPVAAKK 13 1 Q9UGI8;Q9UGI8-2;F8W7T0 Q9UGI8 TES Testin 0 1 ;;; NVMILTNPVAAK(1)K;NVMILTNPVAAK(1)K;NVMILTNPVAAK(1)K;NVMILTNPVAAK(1)K 182.23 3.06E-09 8674000 7342.5 6485.43 7157.1 6072.9 6521.3 10073.3 7499.4 10326.2 8236.6 6472.8 FALSE TRUE FALSE 6761.333377 7046.001671 7422.348422 6047.771949 6443.537757 7983.984031 7709.81298 13474.61084 7333.065587 6697.729318 1.009496362 1.051998571 1.108188771 0.902958549 0.962048099 1.1920434 1.151108475 2.011817767 1.094858457 1 12.70945636 -3.40379246 1.23564303 1.00879195 7.525995772 0.931116052 0.078626266 1.540156611 0.400319119 0.010258174 21.3217328 0.000394646 3.40379246 6.517203822 up QIESSDYDSSSSK(ac)GK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 QIESSDYDSSSSKGKK 16 2 Q9UNL4-8;Q9UNL4-3;Q9UNL4-6;Q9UNL4-2;Q9UNL4 Q9UNL4-8 ING4 Inhibitor of growth protein 4 0 2 ; QIESSDYDSSSSK(1)GK(1)K;QIESSDYDSSSSK(1)GK(1)K 383.79 0 80791000 8062.5 6201 6717.1 5689.7 7236.4 7881.1 6084.8 5448.6 7070 5514 FALSE TRUE FALSE 7424.344617 6736.986809 6966.041635 5666.157529 7150.110656 6246.471022 6255.523112 7109.853058 6294.438688 5705.61109 1.301235661 1.180765163 1.220910701 0.99308513 1.253171754 1.094794392 1.096380916 1.246115963 1.103201496 1 12.4781657 -9.606943484 1.429336117 1.000637509 1.185678705 0.181341121 0.092251254 0.368264747 1.357816013 0.064268482 0.01503455 2.47E-10 9.606943484 0.185041196 QIESSDYDSSSSK(ac)GKK ddPTM_HeLa_Curcumin_4h_R1 2 QIESSDYDSSSSKGKK 16 2 Q9UNL4-8;Q9UNL4-3;Q9UNL4-6;Q9UNL4-2;Q9UNL4 Q9UNL4-8 ING4 Inhibitor of growth protein 4 0 1 ; QIESSDYDSSSSK(1)GKK;QIESSDYDSSSSK(1)GKK 233.48 3.03E-37 49106000 12004.2 9322.3 10022.4 10335.5 10555.5 13074.2 11778.3 13166.8 12341.1 10429 FALSE TRUE FALSE 11054.0549 10128.07807 10393.83896 10292.73444 10429.63256 10362.46354 12108.7674 17181.29671 10987.31221 10791.40697 1.024338618 0.93853175 0.963158834 0.95378985 0.966475695 0.96025139 1.122074946 1.592127583 1.018153817 1 13.39759535 -4.272440167 2.671463063 0.993192405 1.70308959 0.972640607 0.030828399 0.059189536 0.561508594 0.00514534 0.091902221 5.34E-05 4.272440167 0.709897185 QIESSDYDSSSSK(ac)GR ddPTM_HeLa_Curcumin_4h_R1 1 QIESSDYDSSSSKGR 15 1 Q9UNL4-4 Q9UNL4-4 ING4 Inhibitor of growth protein 4 0 1 QIESSDYDSSSSK(1)GR 256.13 1.52E-61 2001000 909.79 745.78 635.65 843.12 855.08 1271.8 911.27 826.66 1088.4 751.64 FALSE TRUE FALSE 837.7791615 810.2419001 659.2077482 839.6313928 844.8837295 1008.014344 936.8377836 1078.704829 969.005243 777.7594341 1.077170041 1.041764156 0.847572809 1.079551538 1.086304701 1.296049009 1.204534131 1.386938919 1.245893268 1 9.603180179 -5.353882502 2.042378478 1.024242328 1.298763246 0.535005393 0.102093603 0.135136446 1.086106366 0.011079482 0.031880874 4.43E-06 5.353882502 0.274520918 QIEYEYK ddPTM_HeLa_Curcumin_4h_R1 1 QIEYEYK 7 0 P20700;E9PBF6;A0A0D9SFE5 P20700 LMNB1 Lamin-B1 0 0 103.56 0.018183 2220800 2285.5 1647.8 1722.5 1872.8 1797 2392.5 1411.5 1308 2128.1 1538.9 FALSE FALSE TRUE 2104.600263 1790.22849 1786.337365 1865.05085 1775.571949 1896.268531 1451.102891 1706.803179 1894.652754 1592.37666 1.321672388 1.12424939 1.121805795 1.171237243 1.115045198 1.190841701 0.911281186 1.071858952 1.189827006 1 10.63696592 -4.770562838 24.99718826 1.15164248 0.991570058 0.372993538 0.084354503 192.4866197 527396.1993 0.016767476 0.051344342 1.70E-05 4.770562838 -0.160072422 QIGDNLIVPGGVK ddPTM_HeLa_Curcumin_4h_R1 1 QIGDNLIVPGGVK 13 0 Q14195-2;Q14195;D6RF19 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 0 0 101.72 0.0056942 0 1308.8 1006.6 1029.9 1334 1029.2 1690.8 1060.2 918.88 1242.7 1090.8 FALSE FALSE TRUE 1205.207099 1093.606019 1068.069 1328.480261 1016.927462 1340.109021 1089.946359 1199.042282 1106.378919 1128.705219 1.067778441 0.968903129 0.946278073 1.176994878 0.900968158 1.187297621 0.965660777 1.062316593 0.980219548 1 10.14045303 QIIVEEAK ddPTM_HeLa_Curcumin_4h_R1 1 QIIVEEAK 8 0 Q9Y281;Q9Y281-3;F8WDN3 Q9Y281 CFL2 Cofilin-2 0 0 105.52 0.00899 2746400 3585.6 2857.9 3111.1 2969.9 2996.9 4375.1 3291.1 3433 3057.9 3108.4 FALSE FALSE TRUE 3301.795976 3104.924141 3226.400103 2957.611341 2961.163925 3467.654942 3383.439408 4479.705896 2722.45602 3216.416669 1.026544853 0.965336417 1.0031039 0.919536131 0.920640648 1.078111234 1.051928204 1.392762928 0.846425168 1 11.6512386 -3.953645437 1.599573182 0.997839319 1.865229981 0.78205168 0.065551453 0.640986779 0.815902879 0.006758782 1.095814203 0.000111264 3.953645437 0.867390663 QILGVIDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 QILGVIDKK 9 1 Q14444-2;Q14444;E9PLA9 Q14444-2 CAPRIN1 Caprin-1 0 1 ; QILGVIDK(1)K;QILGVIDK(1)K 100.02 0.003277 5221000 1146.5 2004.83 1342.99 1250.22 2352.6 3239.1 2748.7 2329.76 3325.8 1514 FALSE TRUE FALSE 1055.753315 2178.118572 1392.762391 1245.046921 2324.546782 2567.274148 2825.821124 3040.093099 2960.968061 1566.611387 0.673908873 1.390337508 0.88902864 0.794738843 1.48380562 1.638743449 1.803779257 1.940553429 1.890046303 1 10.61343163 -5.508049147 1.845646696 0.884935303 1.834902122 0.31672792 0.37422645 0.11752294 0.787936642 0.032598166 0.087442238 3.10E-06 5.508049147 0.949966819 TSEVYS(ph)DDEEEEEDDKSSEK ddPTM_HeLa_Curcumin_4h_R1 2 TSEVYSDDEEEEEDDKSSEK 20 1 Q92541 Q92541 RTF1 RNA polymerase-associated protein RTF1 homolog 1 0 T(0.007)S(0.002)EVYS(0.991)DDEEEEEDDKSSEK;TSEVYS(0.999)DDEEEEEDDKSSEK ; 140.17 4.07E-05 67305000 4229 3455.9 3965.8 4663.1 4227.7 4196 2762.3 582.38 4029.1 3007.5 TRUE FALSE FALSE 3894.270188 3754.612597 4112.776037 4643.805328 4177.287439 3325.702301 2839.802704 759.9449811 3587.11781 3112.010401 1.251367986 1.206491018 1.321581713 1.492220375 1.342311529 1.068666834 0.912529953 0.244197443 1.152668966 1 11.60363117 -4.283380015 1.90706652 1.183435553 1.70E-17 0.82593329 0.136932038 0.305866907 1.183813123 0.02499186 0.628029281 5.21E-05 4.283380015 -1.183435553 down S(ph)TSQGS(ph)INSPVYSR ddPTM_HeLa_Curcumin_4h_R1 1 STSQGSINSPVYSR 14 0 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4;A0A494C1P1;A0A494C1G0;H0Y7N6;F6XFR5 F8W8M4 ABLIM1 Actin-binding LIM protein 1 2 0 S(0.905)T(0.083)S(0.013)QGS(0.995)INS(0.003)PVYSR 139.21 0.001887 7623100 2906.4 2264.8 2509.1 3199.3 2759.2 3823.3 3358.9 6813.3 2722.4 2716 TRUE FALSE FALSE 2676.355373 2460.55922 2602.089453 3186.062144 2726.298342 3030.304483 3453.141694 8890.643805 2423.759531 2810.380798 0.952310582 0.875525204 0.92588501 1.133676314 0.970081472 1.078254052 1.228709539 3.163501477 0.862431003 1 11.45654991 -4.241155072 3.083906926 0.983656895 3.5612391 0.985092639 0.080252712 0.030218758 0.411985035 0.010423713 0.193333845 5.74E-05 4.241155072 2.577582205 up QIS(ph)DGEREELNLTANR ddPTM_HeLa_Curcumin_4h_R1 1 QISDGEREELNLTANR 16 1 O95816-2;O95816 O95816-2 BAG2 BAG family molecular chaperone regulator 2 1 0 QIS(1)DGEREELNLTANR 139.34 0.0038211 4467200 1809.7 2186 1456.8 1876.7 1774.8 1989.4 1647.5 1716 2063.2 1789.9 TRUE FALSE FALSE 1666.460335 2374.948099 1510.79029 1868.934713 1753.636669 1576.776015 1693.724416 2239.200501 1836.872122 1852.098892 0.899768551 1.282300913 0.815717938 1.009090131 0.946837492 0.851345477 0.91448919 1.209006987 0.991778641 1 10.85494542 -4.25486072 23.97772542 0.959341154 1.209007192 0.259345841 0.121445847 416.0591788 1516366.991 0.015608577 0.194997196 5.56E-05 4.25486072 0.249666038 EGLT(ph)SIEEVTK ddPTM_HeLa_Curcumin_4h_R1 1 EGLTSIEEVTK 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 EGLT(0.619)S(0.381)IEEVTK 145.09 0.0029044 9052900 3640.9 2385.6 2878.5 3439.7 3096.4 5047.9 5111.4 18576 2753.7 2234.3 TRUE FALSE FALSE 3352.718923 2591.800634 2985.179742 3425.467433 3059.477452 4000.908638 5254.812127 24239.73689 2451.625999 2311.941759 1.450174474 1.121049276 1.291200235 1.481640885 1.323336732 1.73054041 2.272899872 10.48457938 1.060418581 1 11.17488934 -4.240862024 3.116431853 1.277831221 12.13856104 0.993863209 0.214947567 0.025044173 0.352293576 0.036996446 0.67993288 5.74E-05 4.240862024 10.86072981 up SVDYNMPRS(ph)PVEMDEDFDVIFDPYAPK ddPTM_HeLa_Curcumin_4h_R1 2 SVDYNMPRSPVEMDEDFDVIFDPYAPK 27 1 O95425-3;A0A6I8PIX7;O95425-2;O95425;O95425-4;A0A0J9YWY6 O95425-3 SVIL Supervillin 1 0 S(0.005)VDY(0.024)NMPRS(0.971)PVEMDEDFDVIFDPYAPK;S(0.035)VDY(0.144)NMPRS(0.821)PVEMDEDFDVIFDPYAPK ; 52.97 0.002788 14331100 4423.3 3308.2 2758.96 3515.9 2910.83 4958.1 4534.9 7523.2 4735.1 3794.6 TRUE FALSE FALSE 4073.191138 3594.146067 2861.209485 3501.352137 2876.120253 3929.734171 4662.137089 9816.989047 4215.671377 3926.462068 1.037369282 0.91536503 0.728699128 0.891732067 0.732496635 1.000833346 1.187363333 2.500212374 1.073656463 1 11.93901424 -4.240854026 2.78758615 0.960623885 2.830951631 0.942342514 0.116219132 0.086675863 0.874151012 0.018105761 0.376962463 5.74E-05 4.240854026 1.870327747 up QIS(ph)RPS(ph)AAGINLMIGSTRY(ph)GDGPR ddPTM_HeLa_Curcumin_4h_R1 1 QISRPSAAGINLMIGSTRYGDGPR 24 2 Q08211;Q08211-2 Q08211 DHX9 ATP-dependent RNA helicase A 3 0 QIS(1)RPS(1)AAGINLMIGS(0.039)T(0.101)RY(0.861)GDGPR 50.776 0.0062999 0 1084.6 549.34 850.59 997.32 746.03 1140.1 861.26 696.8 1232.3 1049.9 TRUE FALSE FALSE 998.7527655 596.8225018 882.1136137 993.1933541 737.1340795 903.6304084 885.4246376 909.2511123 1097.119773 1086.383947 0.919336822 0.549366091 0.811972246 0.914219468 0.678520777 0.831778131 0.815019994 0.836951904 1.009882166 1 10.08531835 -7.492173461 15.92929891 0.964422781 0.779774138 0.478064672 0.096436855 3.726818175 1933.802786 0.016385926 0.018036606 3.22E-08 7.492173461 -0.184648644 QISDGEREELNLTANR ddPTM_HeLa_Curcumin_4h_R1 1 QISDGEREELNLTANR 16 1 O95816-2;O95816 O95816-2 BAG2 BAG family molecular chaperone regulator 2 0 0 121.92 0.00070712 7590300 281.55 283.04 317.62 320.13 289.48 236.12 306.85 245.15 270.07 223.3 FALSE FALSE TRUE 259.2650204 307.5047164 329.3912766 318.8053869 286.0281401 187.1460504 315.4593852 319.8951065 240.4439967 231.0596584 1.122069608 1.330845542 1.425568093 1.379753563 1.237897355 0.809946884 1.365272447 1.384469746 1.040614352 1 7.852121586 -7.574462177 2.220787174 1.04450452 1.268835214 0.271051506 0.167694613 0.303469507 3.065296491 0.033948321 0.035891644 2.66E-08 7.574462177 0.224330694 RTADS(ph)SSSEDEEEYVVEK ddPTM_HeLa_Curcumin_4h_R1 1 RTADSSSSEDEEEYVVEK 18 1 P45973;F8VNY3 P45973 CBX5 Chromobox protein homolog 5 1 0 RT(0.002)ADS(0.251)S(0.251)S(0.251)S(0.246)EDEEEYVVEK 141.45 0.00013033 18036000 5816.4 4753.4 4882.1 5115.4 5109.3 6142.5 3695.5 845 6125.6 4592.7 TRUE FALSE FALSE 5356.025803 5164.262715 5063.034921 5094.23383 5048.374934 4868.47626 3799.185784 1102.63661 5453.637005 4752.295983 1.127039608 1.086687936 1.065387118 1.071952136 1.062302296 1.024447189 0.799442164 0.232021872 1.147579407 1 12.21440898 -4.28304696 1.857769318 1.064613921 1.85E-13 0.976330142 0.039962536 0.097000422 0.350406426 0.006809349 0.175988677 5.21E-05 4.28304696 -1.064613921 down QISLAPETLDSSGDVS(ph)PGPR ddPTM_HeLa_Curcumin_4h_R1 1 QISLAPETLDSSGDVSPGPR 20 0 Q8TER5;Q8TER5-2 Q8TER5 ARHGEF40 Rho guanine nucleotide exchange factor 40 1 0 QISLAPETLDS(0.095)S(0.32)GDVS(0.585)PGPR 122.1 0.00053977 0 637.36 483.37 465.34 522.6 410.95 779.63 461.93 727.94 690.11 487.52 TRUE FALSE FALSE 586.9122835 525.1503489 482.5859098 520.4376197 406.0496897 617.9259498 474.8905126 949.885555 614.4066596 504.4612837 1.163443662 1.041012196 0.956636169 1.031670093 0.804917449 1.224922446 0.941381485 1.882970182 1.217946113 1 8.97859974 -4.256878769 24.98941303 1.05004606 1.882970518 0.803698804 0.124569885 139.3585231 763573.8811 0.015769213 0.168480198 5.54E-05 4.256878769 0.832924458 QITLK(ac)TTPASGER ddPTM_HeLa_Curcumin_4h_R1 1 QITLKTTPASGER 13 1 P12270 P12270 TPR Nucleoprotein TPR 0 1 QITLK(1)TTPASGER 140.01 0.00056105 2969900 266.79 156.95 169.85 185.52 246.45 295.18 222.02 310.35 298.95 125.17 FALSE TRUE FALSE 245.67329 170.5160586 176.1447904 184.7523674 243.5112447 233.9563406 228.2492837 404.9742863 266.1559329 129.5196482 1.896803253 1.316526574 1.35998509 1.426442783 1.880110455 1.806338605 1.762275353 3.126740166 2.054946386 1 7.017027162 -1.085767764 0.71851038 1.429021354 200 0.652905241 0.324604555 121.6275743 0.643265859 0.058306179 38842.61098 0.082079034 1.085767764 198.5709786 QITQEEDDS(ph)DEEVAPENFFSLPEK ddPTM_HeLa_Curcumin_4h_R1 3 QITQEEDDSDEEVAPENFFSLPEK 24 0 Q92733 Q92733 PRCC Proline-rich protein PRCC 1 0 QITQEEDDS(1)DEEVAPENFFSLPEK;QIT(0.001)QEEDDS(0.999)DEEVAPENFFSLPEK;QIT(0.001)QEEDDS(0.795)DEEVAPENFFS(0.204)LPEK ;; 123.72 1.26E-05 20719000 7674 6819.1 7483.3 7074.1 8214.3 7774.1 6624.4 6924.7 7202.6 6648 TRUE FALSE FALSE 7066.594802 7408.512619 7760.637681 7044.829249 8116.349837 6161.664028 6810.262835 9036.009153 6412.4928 6879.017505 1.027268036 1.076972491 1.128160769 1.024103986 1.179870502 0.895718614 0.990005161 1.313561006 0.932181492 1 12.74798681 -4.256726913 24.67155878 1.028002425 1.313561146 0.532110426 0.080260827 223.2150034 1168566.423 0.010000434 0.107230184 5.54E-05 4.256726913 0.285558721 QITTS(ph)PITVR ddPTM_HeLa_Curcumin_4h_R1 2 QITTSPITVR 10 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 0 QIT(0.018)T(0.22)S(0.761)PIT(0.001)VR;QIT(0.061)T(0.211)S(0.727)PIT(0.001)VR ; 136.81 0.0019569 97738000 6601.6 5709.5 6050.1 5977.6 6884.4 7058.9 4806.1 3009.5 7019.2 5827.6 TRUE FALSE FALSE 6079.076394 6203.003739 6274.322028 5952.866275 6802.308026 5594.80457 4940.946231 3927.082696 6249.211321 6030.108666 1.008120538 1.028671966 1.040498999 0.987190547 1.128057288 0.927811567 0.819379302 0.651245759 1.036334777 1 12.55796829 -4.574611727 1.858648218 1.014584496 0.637667945 0.889710854 0.042786037 0.104966468 0.565442654 0.005843231 0.055198571 2.66E-05 4.574611727 -0.376916551 QITVNDLPVGR ddPTM_HeLa_Curcumin_4h_R1 2 QITVNDLPVGR 11 0 A0A0A0MSI0;Q06830;A0A0A0MRQ5;P32119 A0A0A0MSI0;P32119 PRDX1;PRDX2 Peroxiredoxin-1;Peroxiredoxin-2 0 0 ; ; 163.9 3.59E-08 83481000 13527.6 11245.7 11247.7 10720.5 11372.6 16551 12503.5 12552.1 12776.2 10895.7 FALSE FALSE TRUE 12456.87619 12217.7282 11664.54966 10676.14141 11236.98917 13118.13603 12854.31456 16379.17751 11374.68282 11274.32476 1.104888891 1.083677156 1.034611819 0.946942867 0.996688441 1.163540727 1.140140525 1.452785675 1.00890147 1 13.46075341 -3.765472413 1.137180939 1.043313715 2.204727712 0.841507833 0.054384185 1.398740058 0.674815271 0.009223851 2.548277376 0.000171604 3.765472413 1.161413997 QIYYSDKYDDEEFEYR ddPTM_HeLa_Curcumin_4h_R1 4 QIYYSDKYDDEEFEYR 16 1 Q5T179;P61024 Q5T179 CKS1B Cyclin-dependent kinases regulatory subunit;Cyclin-dependent kinases regulatory subunit 1 0 0 ;;; ;;; 145.52 0.00031975 129921000 9823.7 7696.4 8467.8 8192.7 8998.1 8875.4 7536.1 6121.9 9201.6 8537 FALSE FALSE TRUE 9046.143779 8361.642522 8781.624117 8158.800778 8890.803534 7034.541994 7747.542684 7988.439128 8192.207501 8833.660115 1.024053865 0.946566023 0.99410935 0.923603656 1.006468827 0.796333785 0.877047858 0.904318145 0.927385409 1 13.10879561 -5.751449928 0.862750258 1.008349562 0.86141033 0.362912744 0.053160181 0.32204768 0.443292835 0.007786444 0.027502922 1.77E-06 5.751449928 -0.146939232 QIYYSDKYFDEHYEYR ddPTM_HeLa_Curcumin_4h_R1 1 QIYYSDKYFDEHYEYR 16 1 P33552 P33552 CKS2 Cyclin-dependent kinases regulatory subunit 2 0 0 116.79 0.00052549 26374000 2851.5 2505.7 2457.3 2227.1 2011.4 4012.9 2134.2 2047.9 2955.5 2726.2 FALSE FALSE TRUE 2625.800766 2722.281543 2548.3697 2217.88485 1987.415369 3180.579305 2194.079908 2672.295283 2631.289044 2820.935247 0.930826317 0.965028015 0.903377595 0.78622324 0.704523569 1.127491072 0.77778457 0.947308268 0.93277187 1 11.46195783 -7.500866166 0.762701386 0.983316404 0.873625092 0.089435945 0.111191834 0.813461518 1.0043881 0.029456767 0.030066027 3.16E-08 7.500866166 -0.109691312 QKDFLDGVYAFEYYPST(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 2 QKDFLDGVYAFEYYPSTPGR 20 1 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 1 0 QKDFLDGVYAFEYYPS(0.051)T(0.949)PGR;QKDFLDGVYAFEYYPS(0.212)T(0.788)PGR ; 177.69 1.55E-07 132096000 9530.5 7297.8 9120.7 7786.2 8376 15418.7 10870.5 11455.5 8580.1 7815.7 TRUE FALSE FALSE 8776.150868 7928.589314 9458.721165 7753.982767 8276.121671 12220.68782 11175.49697 14948.22922 7638.884496 8087.294993 1.085177538 0.980375925 1.169577859 0.958785697 1.023348558 1.511097076 1.381858456 1.848359585 0.944553711 1 12.98144152 -4.452871284 0.869363271 1.03446662 2.092512704 0.840867735 0.113271381 0.458999732 0.306682912 0.016427695 0.431946024 3.52E-05 4.452871284 1.058046084 QKEDVEVVGGS(ph)DGEGAIGLSSDPK ddPTM_HeLa_Curcumin_4h_R1 1 QKEDVEVVGGSDGEGAIGLSSDPK 24 1 Q8NHZ8 Q8NHZ8 CDC26 Anaphase-promoting complex subunit CDC26 1 0 QKEDVEVVGGS(0.998)DGEGAIGLS(0.001)S(0.001)DPK 97.312 1.10E-05 103610000 6170.4 5050.9 4762 5416.3 5487.3 6410.4 4698.8 3753.1 5707.6 4972.3 TRUE FALSE FALSE 5682.006329 5487.47729 4938.483909 5393.888786 5421.867531 5080.81078 4830.635682 4897.402913 5081.49056 5145.087055 1.104355722 1.066547025 0.959844577 1.048357147 1.053795101 0.987507252 0.938883177 0.951860068 0.987639374 1 12.32897977 -5.04850163 2.999535815 1.044969217 0.945861945 0.388723638 0.041036667 0.188081102 3.341095245 0.006811029 0.021520862 8.94E-06 5.04850163 -0.099107272 QKEDVEVVGGSDGEGAIGLS(ph)SDPK ddPTM_HeLa_Curcumin_4h_R1 1 QKEDVEVVGGSDGEGAIGLSSDPK 24 1 Q8NHZ8 Q8NHZ8 CDC26 Anaphase-promoting complex subunit CDC26 1 0 QKEDVEVVGGS(0.041)DGEGAIGLS(0.48)S(0.48)DPK 61.511 0.0021198 329450000 10104 7453.8 8909.5 8641.8 8881.1 9543.7 7898.9 6726.3 9446 8058.6 TRUE FALSE FALSE 9304.257738 8098.073259 9239.693908 8606.042521 8775.198683 7564.22904 8120.521875 8777.117906 8409.797433 8338.63575 1.115800956 0.971150857 1.108058223 1.032068408 1.052354239 0.907130287 0.973842978 1.0525844 1.008533972 1 13.02559565 -5.323107509 24.27024396 1.051665229 0.977451535 0.206739124 0.054123271 170.5669315 67128.34207 0.008335656 0.0186391 4.75E-06 5.323107509 -0.074213694 QKEENNTDLPYLEESTLTTAALS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 QKEENNTDLPYLEESTLTTAALSPSK 26 1 A0A087WU78;A0A087WWC4;Q6T4R5-4;Q6T4R5-3;Q6T4R5-2;Q6T4R5 A0A087WU78 NHS Nance-Horan syndrome protein 1 0 QKEENNTDLPYLEES(0.019)T(0.019)LT(0.049)T(0.013)AALS(0.824)PS(0.075)K;QKEENNTDLPY(0.007)LEES(0.134)T(0.134)LT(0.008)T(0.008)AALS(0.396)PS(0.314)K ; 84.299 3.03E-05 22858000 5786.8 4895.1 5615.3 5928.4 5514.9 7191.1 5879.2 3684.7 6584.5 5530 TRUE FALSE FALSE 5328.768674 5318.210632 5823.407958 5903.869852 5449.138419 5699.5848 6044.154529 4808.148068 5862.196824 5722.167088 0.9312501 0.929404988 1.01769275 1.031754187 0.952285792 0.996053543 1.056270192 0.840266982 1.024471452 1 12.48234591 -4.238045518 24.36682116 0.977334622 0.840266762 0.497724404 0.043537994 3432.953482 3575656.616 0.006233674 0.468312597 5.78E-05 4.238045518 -0.13706786 QKFNDS(ph)EGDDTEETEDYR ddPTM_HeLa_Curcumin_4h_R1 4 QKFNDSEGDDTEETEDYR 18 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 QKFNDS(0.795)EGDDT(0.117)EET(0.089)EDYR;QKFNDS(0.97)EGDDT(0.015)EET(0.015)EDYR;QKFNDS(0.891)EGDDT(0.088)EET(0.02)EDYR;QKFNDS(0.856)EGDDT(0.074)EET(0.064)EDY(0.006)R ;;; 107.83 0.00038303 378483000 10113.3 7812.7 8186.5 9242.3 10160 10847.5 9104.9 8827.7 9628.4 7450.3 TRUE FALSE FALSE 9312.821633 8487.994975 8489.898892 9204.057811 10038.84864 8597.606223 9360.358989 11519.22509 8572.188609 7709.19737 1.208014426 1.101021879 1.101268846 1.193906106 1.302191156 1.115240123 1.214180743 1.494218469 1.111943072 1 12.91236495 -1 0.055713261 0.683147886 2.20992821 0.473804894 0.094383615 231.8608323 0.97963751 5.903419037 29.53419786 0.1 1 1.526780324 QKFNDS(ph)EGDDTEETEDYRQFR ddPTM_HeLa_Curcumin_4h_R1 1 QKFNDSEGDDTEETEDYRQFR 21 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 QKFNDS(0.98)EGDDT(0.019)EET(0.001)EDYRQFR 53.551 0.015095 39220000 938.5 642.62 914.29 1006.5 629.76 1139.1 870.36 894.79 1855.2 1233.6 TRUE FALSE FALSE 864.2167347 698.1652093 948.1743917 1002.33537 622.2505233 902.8378197 894.7799591 1167.607352 1651.689201 1276.467508 0.677037785 0.546951023 0.742811224 0.785241585 0.487478545 0.707294008 0.700981383 0.914717644 1.293953188 1 10.3179411 -9.112858261 0.84434256 1.003286114 0.689358219 0.549653745 0.149124484 0.393571226 0.501008608 0.077315579 0.021880965 7.71E-10 9.112858261 -0.313927895 QKIDDRDS(ph)DEEGASDR ddPTM_HeLa_Curcumin_4h_R1 3 QKIDDRDSDEEGASDR 16 2 Q8TDD1-2;Q8TDD1 Q8TDD1-2 DDX54 ATP-dependent RNA helicase DDX54 1 0 QKIDDRDS(0.975)DEEGAS(0.025)DR;QKIDDRDS(0.999)DEEGAS(0.001)DR;QKIDDRDS(0.986)DEEGAS(0.014)DR ;; 78.228 0.010067 135923400 7684 6303 6440.5 7090.6 7134.1 8082.3 6145.75 4648.75 7379.9 6582.3 TRUE FALSE FALSE 7075.803292 6847.803234 6679.190596 7061.260976 7049.030517 6405.939874 6318.183205 6066.132475 6570.343434 6811.034435 1.038873516 1.005398416 0.980642612 1.036738405 1.034942722 0.940523783 0.927639298 0.890633065 0.964661608 1 12.73365821 -5.095570442 3.200994873 1.017200478 0.91148689 0.717546915 0.025615779 0.07928252 1.539275187 0.00318078 0.009448227 8.02E-06 5.095570442 -0.105713587 QKIPS(ph)S(ph)ASS(ph)GS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 QKIPSSASSGSK 12 1 B5A927 B5A927 VEGFR3 4 0 QKIPS(0.993)S(0.635)AS(0.635)S(0.764)GS(0.973)K 55.567 0.0094099 0 922.45 587.98 635.47 638.94 680.44 884.64 838.86 675.21 855.41 703.3 TRUE FALSE FALSE 849.4371091 638.8023712 659.0210772 636.2962356 672.3261974 701.1556921 862.3961539 881.0784207 761.5736631 727.7396227 1.167226688 0.877789736 0.905572621 0.87434601 0.923855424 0.963470547 1.185033942 1.210705578 1.046491959 1 9.507278552 -4.709614219 8.00440686 1.021948721 1.199992087 0.401579794 0.095732076 0.278375907 37.22303162 0.01733643 0.064994139 1.95E-05 4.709614219 0.178043367 QKKKY(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 QKKKYPK 7 3 Q52LR7 Q52LR7 EPC2 Enhancer of polycomb homolog 2 1 0 QKKKY(1)PK 48.504 0.0090467 0 924.7 798.66 861.18 693.37 857.09 1342.3 971.95 984.12 856.94 815.87 TRUE FALSE FALSE 851.5090193 867.6926116 893.0960884 690.5010187 846.8697615 1063.891849 999.2203011 1284.173658 762.935826 844.2214218 1.00863233 1.027802173 1.057893185 0.817914591 1.00313702 1.260204754 1.183599794 1.521133703 0.903715312 1 9.721477627 -4.249554286 0.959286972 0.997194296 1.775163181 0.775790599 0.089611821 0.678629945 0.463460969 0.012732635 0.549306105 5.63E-05 4.249554286 0.777968885 QKLKS(ph)T(ph)AQRIL ddPTM_HeLa_Curcumin_4h_R1 1 QKLKSTAQRIL 11 3 J3QR18 J3QR18 TOP3A 2 0 QKLKS(1)T(1)AQRIL 60.436 0.0096378 0 136.46 0 132.67 170.02 162.36 0 118.46 0 0 72.585 TRUE FALSE FALSE 125.659047 0 137.5868669 169.3165023 160.423963 0 121.7836688 0 0 75.10732335 1.673059848 0 1.831870193 2.254327471 2.135929706 0 1.621461974 0 0 1 6.23088168 -5.256408565 24.95181987 1.382070325 0.648584857 0.11926711 0.858496416 573.9035666 2846431.985 0.104063472 0.256528201 5.54E-06 5.256408565 -0.733485468 QKS(ph)DAEEDGGTVSQEEEDRKPK ddPTM_HeLa_Curcumin_4h_R1 1 QKSDAEEDGGTVSQEEEDRKPK 22 3 P27824-3;P27824;P27824-2 P27824-3 CANX Calnexin 1 0 QKS(0.787)DAEEDGGT(0.21)VS(0.002)QEEEDRKPK 57.414 0.0060819 133420000 2740.4 2455.8 3288.5 4225.9 3125.2 4428.5 1739.2 1376.9 5058.8 3134.6 TRUE FALSE FALSE 2523.494448 2668.068409 3410.374703 4208.414346 3087.934031 3509.979181 1787.997271 1796.710472 4503.862296 3243.527117 0.778009358 0.822582427 1.05144017 1.297480858 0.952029664 1.082148863 0.551250909 0.553937244 1.388569337 1 11.66334778 -4.748440715 24.94701763 0.941870488 0.552593761 0.429415211 0.200561253 148.7182968 285414.5192 0.023041235 0.085122803 1.78E-05 4.748440715 -0.389276727 QKS(ph)LTNLSFLTDSEK ddPTM_HeLa_Curcumin_4h_R1 1 QKSLTNLSFLTDSEK 15 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 QKS(0.998)LT(0.002)NLSFLTDSEK 94.454 0.0063678 0 913.28 1025.3 914.46 981.71 932.47 1555.4 1165.8 644.52 1059.5 987.42 TRUE FALSE FALSE 840.9929243 1113.922363 948.350692 977.6479441 921.3509043 1232.792507 1198.50921 841.031181 943.2755007 1021.732772 0.823104581 1.090228673 0.928178794 0.956852879 0.901753306 1.206570388 1.173016315 0.823142023 0.923211555 1 9.996802201 -5.29017095 24.72223022 0.931195836 1.078120295 0.178283111 0.115683098 648.0943396 557655.2624 0.017081456 0.038202019 5.13E-06 5.29017095 0.146924459 QKS(ph)PEIHR ddPTM_HeLa_Curcumin_4h_R1 1 QKSPEIHR 8 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 QKS(1)PEIHR 72.2 0.018034 207210000 4903.2 8437.4 4244.6 3603.4 2848.3 3770 3091.1 3029.9 2743.8 3808.6 TRUE FALSE FALSE 4515.106546 9166.69126 4401.90861 3588.490086 2814.335883 2988.059503 3177.827947 3953.702562 2442.812005 3940.948567 1.1456903 2.326011392 1.116966775 0.910565064 0.714126519 0.758208196 0.806361183 1.003236276 0.619853815 1 11.94432721 -6.225890188 4.270106937 1.188691016 0.819336199 0.188720608 0.413477581 0.316122388 13.30901856 0.061509337 0.101933023 5.94E-07 6.225890188 -0.369354818 QKVDSLLENLEK ddPTM_HeLa_Curcumin_4h_R1 2 QKVDSLLENLEK 12 1 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7;G3V576;B7ZW38;A0A0G2JPF8;P0DMR1;A0A0G2JNQ3;O60812;B2RXH8 P07910;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL1;HNRNPCL2 Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoprotein C-like 1;Heterogeneous nuclear ribonucleoprotein C-like 2 0 0 ; ; 139.48 0.0010786 28757200 6883.4 6228.5 6398.5 6103.7 6749.7 7607.8 7061.4 5933.6 6214.8 5976.4 FALSE FALSE TRUE 6338.571627 6766.863786 6635.634039 6078.444507 6669.214236 6029.856522 7259.523879 7742.727325 5533.051989 6184.079455 1.024982242 1.094239464 1.073018885 0.982918242 1.078448989 0.975061295 1.173905337 1.252042019 0.894725242 1 12.59434314 -4.613666568 4.296061756 1.023186811 1.236381837 0.665706511 0.056820329 0.063885673 2.085758601 0.005606353 0.023930548 2.43E-05 4.613666568 0.213195025 QLADETLLK ddPTM_HeLa_Curcumin_4h_R1 1 QLADETLLK 9 0 P20700;E9PBF6;A0A0D9SFE5 P20700 LMNB1 Lamin-B1 0 0 143.03 1.30E-05 1362800 824.49 463.23 720.89 687.66 759.75 793.54 528.37 672.06 991.21 650.8 FALSE FALSE TRUE 759.2307465 503.2695371 747.6068176 684.8146451 750.6904775 628.950859 543.1946402 876.9680002 882.4767429 673.4152516 1.127433251 0.747339084 1.11017209 1.016927733 1.114751226 0.933971806 0.806626578 1.302269288 1.310449594 1 9.395352586 QLAEEDAAR ddPTM_HeLa_Curcumin_4h_R1 1 QLAEEDAAR 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 114.4 0.0021852 2093900 2376.4 2089.9 2246.2 2369.6 2356.1 2667.3 2068.4 1943.1 2588 1945.9 FALSE FALSE TRUE 2188.305432 2270.541644 2329.446148 2359.795223 2328.005046 2114.071913 2126.433737 2535.542245 2304.102875 2013.51988 1.086805973 1.127647989 1.156902483 1.17197513 1.15618677 1.049938436 1.056077846 1.25925861 1.14431593 1 10.975504 -8.208706418 0.676463392 1.006716662 1.136961107 0 0.070812467 0.436727489 0.438587766 0.02508026 0.014526759 6.18E-09 8.208706418 0.130244445 QLAEEDLAQQR ddPTM_HeLa_Curcumin_4h_R1 2 QLAEEDLAQQR 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 110.84 0.0043215 4978200 2659.1 2596 2266.1 2584.4 2269.34 2886.9 2223.1 2436.9 2616.4 2405.8 FALSE FALSE TRUE 2448.629429 2820.386672 2350.083659 2573.706438 2242.279603 2288.124398 2285.474203 3179.899592 2329.387466 2489.401371 0.983621789 1.132957789 0.944035657 1.033865598 0.900730444 0.919146436 0.918081845 1.277375207 0.935721934 1 11.28158314 -4.253005484 24.62772697 0.986373024 1.277375388 0.644883415 0.066941502 410.6584701 1199126.326 0.008728363 0.131646841 5.58E-05 4.253005484 0.291002364 QLAEGTAQQR ddPTM_HeLa_Curcumin_4h_R1 2 QLAEGTAQQR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 121.5 0.0027151 3018900 1498.29 1198.28 1502.18 1155.5 1252.4 1777.01 1324.1 1292.26 1638.52 1354.97 FALSE FALSE TRUE 1379.698766 1301.853984 1557.852112 1150.718847 1237.465948 1408.438095 1361.250682 1686.264125 1458.778455 1402.055107 0.984054592 0.928532679 1.111120458 0.820737246 0.882608638 1.004552594 0.970896704 1.202708879 1.040457289 1 10.45332734 -4.260493763 24.54840085 0.976931318 1.202708968 0.447650786 0.07685071 42.10860452 1092927.352 0.009836017 0.079978836 5.49E-05 4.260493763 0.22577765 QLAELETEDGMQES(ph)P ddPTM_HeLa_Curcumin_4h_R1 3 QLAELETEDGMQESP 15 0 Q96QG7-2;Q96QG7 Q96QG7-2 MTMR9 Myotubularin-related protein 9 1 0 QLAELETEDGMQES(1)P;QLAELETEDGMQES(1)P;QLAELETEDGMQES(1)P ;; 167.69 0.00020606 7993300 5366.3 5435.6 5018.3 5198.6 4708.4 6109.9 5101.1 4592.9 5457.5 5037.7 TRUE FALSE FALSE 4941.551693 5905.429043 5204.282613 5177.089571 4652.255405 4842.637867 5244.223137 5993.254067 4858.825904 5212.7597 0.947972279 1.132879585 0.998373781 0.993157151 0.892474557 0.928996951 1.00603585 1.149727671 0.932102415 1 12.34783164 -4.281239881 3.928825434 0.980345062 1.162496907 0.407359845 0.061609574 0.171518511 5.310628674 0.008477839 0.08606576 5.23E-05 4.281239881 0.182151844 QLDDLKVELSQLR ddPTM_HeLa_Curcumin_4h_R1 1 QLDDLKVELSQLR 13 1 F2Z388;P42766 F2Z388 RPL35 60S ribosomal protein L35 0 0 119.74 0.0021821 18486000 1834.5 1501.5 1713.5 1589.4 1465.3 2359 1921.6 1712.3 1957.8 2005.7 FALSE FALSE TRUE 1689.297389 1631.282969 1777.003817 1582.823484 1447.827255 1869.716809 1975.514924 2234.372388 1743.034238 2075.397926 0.813963129 0.786009733 0.856223183 0.762660242 0.697614292 0.900895575 0.951872843 1.076599509 0.83985544 1 11.01917226 -4.423421183 2.269981352 0.870887176 1.09194181 0.409476232 0.084093128 0.479993273 3.630393518 0.015585451 0.182460178 3.77E-05 4.423421183 0.221054635 QLDWRPER ddPTM_HeLa_Curcumin_4h_R1 1 QLDWRPER 8 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 0 0 98.582 0.013696 3737900 1409.6 1139.9 1252.9 1221.5 1237.5 1626.8 1264.9 1078.2 1290.7 1164.1 FALSE FALSE TRUE 1298.028673 1238.427877 1299.333576 1216.445757 1222.743621 1289.383342 1300.38969 1406.938217 1149.113439 1204.552388 1.077602506 1.028122885 1.078685816 1.009873683 1.015102068 1.070425292 1.079562585 1.168017456 0.953975477 1 10.23428143 QLEAIDQLHLEYAK ddPTM_HeLa_Curcumin_4h_R1 1 QLEAIDQLHLEYAK 14 0 O43707;O43707-2;F5GXS2;O43707-3 O43707 ACTN4 Alpha-actinin-4 0 0 81.311 0.014291 17475000 3928 2166 3467.1 2648 3216 4161.2 4004.7 3745.8 2331.2 2512.7 FALSE FALSE TRUE 3617.094655 2353.219388 3595.593776 2637.043278 3177.6513 3298.120214 4117.061104 4887.877176 2075.473192 2600.016138 1.391181617 0.905078762 1.382912099 1.014241119 1.222165991 1.268499901 1.583475211 1.879941092 0.798253965 1 11.34430486 -4.532111954 1.593888493 1.170597879 1.968188084 0.636401582 0.189494675 0.301635371 1.04282583 0.025008873 0.316613252 2.94E-05 4.532111954 0.797590205 QLEDELVSLQK ddPTM_HeLa_Curcumin_4h_R1 2 QLEDELVSLQK 11 0 P09493-3;P09493-9;H0YKP3;A0A087WTJ7;P09493-4;P09493-10;A0A0S2Z4G6;P09493 P09493-3;P09493-4 TPM1 Tropomyosin alpha-1 chain 0 0 ; ; 176.42 1.45E-34 0 334.59 403.9 442.66 429.36 513.366 754.78 463.95 621.18 431.3 323.01 FALSE FALSE TRUE 308.1068484 438.8113163 459.065369 427.5834221 507.2444457 598.2301199 476.9671883 810.5749224 383.9874691 334.2345735 0.92182818 1.312884277 1.373482594 1.27929142 1.51763009 1.789851103 1.427043239 2.425167792 1.148856221 1 8.384717164 -1 0.264795514 0.915166589 9.93121673 0.757808754 0.202208404 14.05792219 0.17767848 0.091546366 58.28460415 0.1 1 9.01605014 up QLEEAEEEAQR ddPTM_HeLa_Curcumin_4h_R1 2 QLEEAEEEAQR 11 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ; ; 193.3 3.16E-16 12032700 3651 3275.3 2886.8 3102.2 3257 4258.8 3308.8 3067 3668.2 3285.9 FALSE FALSE TRUE 3362.019497 3558.402338 2993.787347 3089.363918 3218.162402 3375.476873 3401.636023 4002.114181 3265.807637 3400.08478 0.988804608 1.046562826 0.880503735 0.90861379 0.946494752 0.992762561 1.000456236 1.177063056 0.960507707 1 11.731355 -4.244002672 3.24422378 0.980662198 1.209141205 0.636389895 0.046624751 0.200594162 3.218698434 0.006843145 0.11719685 5.70E-05 4.244002672 0.228479007 QLEEAEEESQR ddPTM_HeLa_Curcumin_4h_R1 2 QLEEAEEESQR 11 0 P35749-4;P35749-3;P35749;P35749-2 P35749-4 MYH11 Myosin-11 0 0 ; ; 161.19 0.0028051 457840000 3899.9 2764.85 2837.82 3398.14 3211.36 3660.6 3092.36 3163.31 3547.3 3364.89 FALSE FALSE TRUE 3591.2188 3003.831314 2942.992106 3384.079397 3173.066629 2901.350297 3179.123299 4127.788657 3158.170065 3481.819677 1.0314201 0.862718806 0.845245411 0.971928391 0.911324228 0.833285628 0.913063741 1.185526259 0.907045843 1 11.76562577 -7.281157017 24.48446582 1.014837273 0.924774028 0.006486437 0.10059483 818.3328991 1016165.749 0.015697365 0.017964811 5.23E-08 7.281157017 -0.090063245 QLEELEEEFCR ddPTM_HeLa_Curcumin_4h_R1 1 QLEELEEEFCR 11 0 M0QZR4;Q92888-2;Q92888;Q92888-3 M0QZR4 ARHGEF1 Rho guanine nucleotide exchange factor 1 0 0 140.78 0.011274 2877000 648.02 819.38 815 1059.2 881.24 900.13 756.38 572.37 872.12 719.72 FALSE FALSE TRUE 596.7285332 890.2035561 845.2046169 1054.817311 870.7317886 713.4328914 777.6019871 746.8829781 776.4506179 744.7302164 0.801268057 1.195336964 1.134913823 1.416375068 1.169190895 0.957974949 1.044139166 1.00289066 1.042593144 1 9.540574084 -7.254698197 24.9530862 0.906154359 1.134040714 0.267436293 0.133944652 429.8500318 1591129.118 0.024294845 0.029390181 5.56E-08 7.254698197 0.227886354 QLEEPGAGTPS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 4 QLEEPGAGTPSPVR 14 0 Q96P11-5;Q96P11;Q96P11-2;Q96P11-4;Q63ZY6-4;Q63ZY6-5;Q63ZY6 Q96P11-5 NSUN5;NSUN5P2 Probable 28S rRNA (cytosine-C(5))-methyltransferase;Putative methyltransferase NSUN5C 1 0 QLEEPGAGT(0.001)PS(0.999)PVR;QLEEPGAGTPS(1)PVR;QLEEPGAGTPS(1)PVR;QLEEPGAGT(0.025)PS(0.975)PVR ;;; 218.34 5.83E-14 250002000 10717.5 9705.4 9680.9 9765.9 10149.8 11551.3 7882 7961.3 10880.8 8845.9 TRUE FALSE FALSE 9869.198566 10544.29153 10039.68267 9725.491293 10028.77026 9155.43017 8103.147707 10388.66372 9687.203462 9153.294367 1.078212736 1.151966834 1.096838173 1.062512676 1.09564599 1.000233337 0.88527118 1.134964452 1.05832972 1 13.16007536 -5.147924209 7.825138479 1.056497363 0.993796959 0.126760696 0.06906158 0.449215721 28.09934793 0.010095797 0.025902038 7.11E-06 5.147924209 -0.062700404 QLEEQLR ddPTM_HeLa_Curcumin_4h_R1 1 QLEEQLR 7 0 P09493-3;H0YKX5;H7BYY1;P09493-2;P09493-8;F5H7S3;B7Z596;H0YL42;P09493-4;P09493-10 P09493-3;P09493-4 TPM1 Tropomyosin alpha-1 chain 0 0 105.14 0.017091 4659600 2382.2 2202.6 2308.3 2216.4 2325.1 2461 1927.2 2374.4 2625.7 2150.1 FALSE FALSE TRUE 2193.646356 2392.982929 2393.847629 2207.229124 2297.374701 1950.560859 1981.272045 3098.34363 2337.667279 2224.815815 0.985990095 1.075586983 1.075975644 0.992095215 1.032613435 0.876729141 0.890533064 1.392629272 1.050723958 1 11.11947019 -4.252192002 24.90503815 0.993857043 1.392629493 0.766665891 0.065312086 411.8738167 1109234.441 0.008836477 0.147544091 5.60E-05 4.252192002 0.39877245 QLEMILNKPGLK ddPTM_HeLa_Curcumin_4h_R1 1 QLEMILNKPGLK 12 1 S4R3Z2;A0A0A0MSS8;P42330;P42330-2;A6NHU4;P17516;H0Y804;Q04828 S4R3Z2;H0Y804 AKR1C3;AKR1C1;AKR1C4 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C1 0 0 94.538 0.0073156 2804100 1100 645.98 859.65 755.55 917.84 1137.2 876.45 1119.5 1144.7 790.94 FALSE FALSE TRUE 1012.933839 701.8156328 891.5093852 752.4237343 906.8953575 901.3319011 901.0408282 1460.830396 1019.129274 818.4251061 1.237662227 0.857519677 1.089298677 0.919355636 1.108098164 1.101300405 1.100944755 1.784928621 1.245232174 1 9.676706592 -4.260942333 5.734188263 1.080613455 1.80742068 0.771085007 0.116317479 0.051980541 7.256473543 0.016594681 0.146867178 5.48E-05 4.260942333 0.726807226 QLFDQVVK ddPTM_HeLa_Curcumin_4h_R1 1 QLFDQVVK 8 0 P26038;V9GZ54;E7EQR4;P15311;E9PQ82;E9PNV3 P26038;E7EQR4 MSN;EZR;RDX Moesin;Ezrin 0 0 152.47 2.40E-05 5997500 4711.6 3641 4201.7 4203.7 4731 5581.8 4577.5 4903 4934.4 3912.5 FALSE FALSE TRUE 4338.671888 3955.711816 4357.418698 4186.306203 4674.585915 4424.07176 4705.93233 6397.902129 4393.108665 4048.459084 1.071684757 0.977090724 1.07631536 1.034049281 1.154658061 1.092779171 1.162400862 1.580330194 1.085131052 1 11.98315718 -1.124265358 0.892858878 1.037319489 200 0.914575115 0.047416613 121.8022232 0.338967643 0.007275069 49267.74334 0.075116379 1.124265358 198.9626805 QLFEELRR ddPTM_HeLa_Curcumin_4h_R1 2 QLFEELRR 8 1 P30613-2;P30613 P30613-2 PKLR Pyruvate kinase PKLR 0 0 ; ; 112.11 0.015649 33751000 9993.4 6496.4 8214.4 8564.7 8836.7 1415.59 4073.9 5393.5 9258.4 7537.1 FALSE FALSE TRUE 9202.411845 7057.919869 8518.83289 8529.261541 8731.328124 1121.980677 4188.20267 7037.953321 8242.776683 7799.013664 1.179945598 0.904975959 1.092296187 1.093633363 1.119542611 0.143861868 0.537016968 0.902415821 1.05689989 1 12.92907596 -5.286869737 24.96852916 1.076178304 0.528690072 0.641644099 0.183447737 315.4338861 309704.9661 0.02564806 0.057370461 5.17E-06 5.286869737 -0.547488232 QLFEEQAK ddPTM_HeLa_Curcumin_4h_R1 1 QLFEEQAK 8 0 Q15046;Q15046-2 Q15046 KARS Lysine--tRNA ligase 0 0 105.78 0.0088434 2644000 707.94 658.81 709.05 598.77 648.69 768.2 676.37 666.03 727.94 677 FALSE FALSE TRUE 651.905802 715.7546008 735.3280167 596.2924484 640.9547954 608.8666606 695.3471218 869.099481 648.0868032 700.5256996 0.930595126 1.021739247 1.049680286 0.851207099 0.914962571 0.869156779 0.992607583 1.240638968 0.925143508 1 9.452294168 -4.274404458 4.247498386 0.958310578 1.259394126 0.670717149 0.061171937 0.096230977 3.937459563 0.008764943 0.085598967 5.32E-05 4.274404458 0.301083548 QLFHPEQLITGK ddPTM_HeLa_Curcumin_4h_R1 1 QLFHPEQLITGK 12 0 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;A0A1W2PQM2;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;Q9NY65-2;Q9NY65;C9J2C0;F8VX09;C9K0S6;P68363;P68363-2;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2 Q9BQE3;P68363;P68366-2 TUBA1C;TUBA1B;TUBA1A;TUBA3E;TUBA8;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 0 134.18 9.09E-05 13976000 7968.5 6702.1 8469.4 7839.3 8874.8 8767 6865.1 6917.2 7329.3 6876.6 FALSE FALSE TRUE 7337.784817 7281.39966 8783.283414 7806.863054 8768.973806 6948.625376 7057.71623 9026.222437 6525.294127 7115.561338 1.031230632 1.023306429 1.234376741 1.097153504 1.232365711 0.976539312 0.991870619 1.268518675 0.917045587 1 12.79676186 -6.955870544 24.97371326 1.01540673 1.123253694 0.320666051 0.097460863 140.111259 79291.30858 0.014382937 0.018902877 1.11E-07 6.955870544 0.107846965 QLFHPEQLITGKEDAANNYAR ddPTM_HeLa_Curcumin_4h_R1 2 QLFHPEQLITGKEDAANNYAR 21 1 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;A0A1W2PQM2;P0DPH7-2;F8VVB9;F8VQQ4;F8VRZ4;F8VS66;F8VWV9;Q9NY65-2;Q9NY65;C9J2C0;F8VX09;C9K0S6;P68363;P68363-2;P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2 Q9BQE3;P68363;P68366-2 TUBA1C;TUBA1B;TUBA1A;TUBA8;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 0 ; ; 82.709 0.00046259 92844500 5207.2 4137.7 4171.3 4462.8 3743.4 5204.2 3705.4 4042.6 5630.4 5073.4 FALSE FALSE TRUE 4795.044625 4495.344351 4325.892047 4444.334116 3698.7624 4124.790257 3809.363551 5275.17013 5012.759207 5249.700272 0.91339398 0.856304954 0.824026482 0.846588164 0.704566396 0.785719192 0.725634485 1.004851678 0.954865792 1 12.35801934 -7.500339033 0.730149528 0.983110712 0.799558306 0.40221791 0.077942401 0.350919531 0.401185071 0.021136521 0.021456531 3.16E-08 7.500339033 -0.183552406 QLGKNGDEET(ph)PHK ddPTM_HeLa_Curcumin_4h_R1 1 QLGKNGDEETPHK 13 1 Q6ZXV5-2;Q6ZXV5 Q6ZXV5-2 TMTC3 Transmembrane and TPR repeat-containing protein 3 1 0 QLGKNGDEET(1)PHK 92.781 0.0087971 8600600 4905.9 4504.6 4273.1 3628.1 6050.2 8155.2 4757.7 5091.6 5584.7 3594.8 TRUE FALSE FALSE 4517.592838 4893.957552 4431.464845 3613.087884 5978.055317 6463.719592 4891.188257 6644.005401 4972.072382 3719.719032 1.214498407 1.315679359 1.191343972 0.971333548 1.607125502 1.737690276 1.314934869 1.786157864 1.336679555 1 11.86097794 -1 0.174341081 0.970569358 4.060719294 0.410786437 0.205768477 31.04095193 0.330923167 0.256097015 25.3315668 0.1 1 3.090149936 QLHDDYFYHDEL ddPTM_HeLa_Curcumin_4h_R1 3 QLHDDYFYHDEL 12 0 Q14257;Q14257-2;A8MXP8 Q14257 RCN2 Reticulocalbin-2 0 0 ;; ;; 142.19 0.00085195 40915500 13814.3 10613.4 11467.1 11511 11666.5 13127 9064.3 5011.3 13425.4 11257.1 FALSE FALSE TRUE 12720.88358 11530.775 11892.08081 11463.37053 11527.38461 10404.31223 9318.619863 6539.222301 11952.66721 11648.28339 1.092082254 0.989911957 1.020929902 0.984125313 0.989620893 0.893205624 0.799999412 0.561389355 1.026131217 1 13.50782974 -3.872798455 0.721087162 1.038545227 3.51E-22 0.961073625 0.028764359 0.730099208 0.182474496 0.006379187 0.700309217 0.00013403 3.872798455 -1.038545227 QLHLEGASLELS(ph)DDDTESK ddPTM_HeLa_Curcumin_4h_R1 4 QLHLEGASLELSDDDTESK 19 0 P35580;P35580-5;P35580-2;P35580-3;P35580-4 P35580 MYH10 Myosin-10 1 0 QLHLEGASLELS(0.995)DDDT(0.004)ESK;QLHLEGASLELS(0.999)DDDT(0.001)ESK;QLHLEGASLELS(0.999)DDDT(0.001)ESK;QLHLEGASLELS(1)DDDTESK ;;; 154.95 1.60E-05 167456000 15968.2 14424 14745.1 13596.4 20177.7 20241.1 16435.1 12212.4 15402.9 13455.4 TRUE FALSE FALSE 14704.30012 15670.74629 15291.56638 13540.1417 19937.09411 16042.8677 16896.22467 15935.90454 13713.24041 13922.97415 1.056117749 1.125531522 1.098297405 0.972503544 1.431956556 1.152258672 1.213549957 1.144576178 0.984936139 1 13.7651798 -5.793572192 24.99999825 1.037978024 1.228059854 0.551906337 0.086415104 106.0309121 82493.99292 0.012147549 0.022020567 1.61E-06 5.793572192 0.19008183 QLIVGVNK ddPTM_HeLa_Curcumin_4h_R1 2 QLIVGVNK 8 0 A0A2U3TZH3;Q05639;A0A2R8Y488;Q5VTE0;P68104;A0A087WV01 A0A2U3TZH3;Q5VTE0 EEF1A2;EEF1A1P5;EEF1A1 Elongation factor 1-alpha 2;Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 0 ; ; 154.01 9.54E-06 331390000 34146 27193 30624 28083 28282 29167 27042 27736 28585 24457 FALSE FALSE TRUE 31443.30807 29543.44175 31758.95238 27966.79999 27944.75562 23117.43542 27800.72574 36192.57872 25449.29702 25306.87893 1.242480677 1.167407559 1.254953346 1.105106642 1.10423556 0.913484254 1.098544227 1.430147859 1.005627643 1 14.62724197 -9.521009944 1.291594966 1.000479566 1.163556523 0.207280939 0.12629935 0.6283632 1.88541203 0.089016854 0.021638388 3.01E-10 9.521009944 0.163076957 QLLDS(ph)DEEQEEDEGR ddPTM_HeLa_Curcumin_4h_R1 2 QLLDSDEEQEEDEGR 15 0 Q9UNS1-2;Q9UNS1 Q9UNS1-2 TIMELESS Protein timeless homolog 1 0 QLLDS(1)DEEQEEDEGR;QLLDS(1)DEEQEEDEGR ; 286.57 2.77E-77 64417000 3402.4 2815 3194.2 3456.4 3704 3302.2 2817.7 1501.48 2501.3 2871.4 TRUE FALSE FALSE 3133.09645 3058.316057 3312.579862 3442.098333 3659.832219 2617.286497 2896.757079 1959.27434 2226.913648 2971.180936 1.054495339 1.029326763 1.114903445 1.158495025 1.231776959 0.880890983 0.974951422 0.659426128 0.749504556 1 11.53682075 -3.989008503 1.324860813 1.0514984 0.264026018 0.419671818 0.129120713 1.240545059 1.17428966 0.013377718 1.558576909 0.000102563 3.989008503 -0.787472383 QLLDS(ph)DEEQEEDEGRNR ddPTM_HeLa_Curcumin_4h_R1 1 QLLDSDEEQEEDEGRNR 17 1 Q9UNS1-2;Q9UNS1 Q9UNS1-2 TIMELESS Protein timeless homolog 1 0 QLLDS(1)DEEQEEDEGRNR 122.53 0.00023553 16153000 735.48 628.9 767.33 593.58 864.7 1028.9 747.15 442.07 719.45 644.53 TRUE FALSE FALSE 677.2659819 683.2593137 795.7679248 591.1239232 854.3890173 815.4945419 768.1130181 576.855108 640.528135 666.9273695 1.015501857 1.02448834 1.193185287 0.886339278 1.281082553 1.222763646 1.151719143 0.864944422 0.960416627 1 9.381385846 -6.96976317 23.05401357 1.007987402 1.106653505 0.127155523 0.127581583 136.7448756 104259.7648 0.01954615 0.025688374 1.07E-07 6.96976317 0.098666103 QLLDS(ph)DEEQEEDEGRNRAPELGAPGIQK ddPTM_HeLa_Curcumin_4h_R1 1 QLLDSDEEQEEDEGRNRAPELGAPGIQK 28 2 Q9UNS1-2;Q9UNS1 Q9UNS1-2 TIMELESS Protein timeless homolog 1 0 QLLDS(1)DEEQEEDEGRNRAPELGAPGIQK 71.002 0.00017734 12254000 1083.4 930.08 1015.5 823.71 794.44 1281.1 727.61 774.37 1120.1 1113.8 TRUE FALSE FALSE 997.6477468 1010.471971 1053.135323 820.3017063 784.9668219 1015.385419 748.0247783 1010.471848 997.2278324 1152.504467 0.865634603 0.876761869 0.913779819 0.711755772 0.681096555 0.881025148 0.649042845 0.876761763 0.865270253 1 10.17055663 -7.767595887 0.346482234 1.015003972 0.745377774 0.273937924 0.091084116 0.746021782 0.260574191 0.078427385 0.055960013 1.71E-08 7.767595887 -0.269626199 GAQPGRHS(ph)VTGYGDCAVGAR ddPTM_HeLa_Curcumin_4h_R1 1 GAQPGRHSVTGYGDCAVGAR 20 1 Q96IF1;H0YJL9 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 0 GAQPGRHS(0.995)VT(0.005)GYGDCAVGAR 78.057 0.0013608 56696000 957.23 919.92 908.42 1042.6 1271.5 1390.1 892.69 338.11 963.63 1095.7 TRUE FALSE FALSE 881.4642354 999.4337857 942.0868443 1038.285997 1256.338193 1101.77759 917.7364788 441.1981825 857.9221999 1133.775493 0.777459242 0.881509427 0.830928918 0.915777421 1.108101384 0.971777567 0.809451681 0.389140694 0.756694958 1 10.14691928 -4.282877166 3.183305855 0.907906953 0.325712319 0.704119044 0.099897727 0.144574473 2.316110153 0.015297354 0.202515507 5.21E-05 4.282877166 -0.582194634 down QLLLSFKPVMQK ddPTM_HeLa_Curcumin_4h_R1 1 QLLLSFKPVMQK 12 1 H0Y3P2;D3DQV9;P78344-2;P78344;H0YE22 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 0 0 80.737 0.0095002 576850 87.878 305.18 133.96 204.77 79.759 265.29 217.84 261.91 67.829 190.16 FALSE FALSE TRUE 80.92236357 331.5583993 138.9246754 203.922716 78.80792602 210.2658636 223.9520041 341.7651533 60.3883284 196.7680458 0.411257647 1.685021559 0.706032704 1.036360935 0.400511809 1.06859761 1.138152301 1.736893568 0.306901093 1 7.620352143 -4.271591245 1.418828324 0.795866071 2.102527472 0.349250651 0.385539714 1.003618795 1.79630038 0.054444239 1.849036783 5.35E-05 4.271591245 1.306661401 AEAPAGPALGLPSPEAES(ph)GVDRGEPEPMEVEEGELEIVPVRR ddPTM_HeLa_Curcumin_4h_R1 2 AEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRR 42 2 Q53F19 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 0 AEAPAGPALGLPS(0.026)PEAES(0.974)GVDRGEPEPMEVEEGELEIVPVRR;AEAPAGPALGLPS(0.234)PEAES(0.766)GVDRGEPEPMEVEEGELEIVPVRR ; 75.965 9.05E-08 151270000 4305.13 2965.7 2980.55 3497 3393.13 4645.51 4286 6127.52 3877.47 3504.83 TRUE FALSE FALSE 3964.374418 3222.041893 3091.011805 3482.530341 3352.669141 3681.97886 4406.253625 7995.77264 3452.121242 3626.622582 1.093131234 0.888441469 0.85231141 0.960268201 0.924460449 1.015263865 1.214974408 2.204743521 0.951883237 1 11.8244109 -4.240696347 2.581010803 1.004255444 2.493746107 0.960662018 0.074954375 0.087924707 0.710671254 0.012743339 0.289558627 5.75E-05 4.240696347 1.489490663 up QLLTLSSELSQAR ddPTM_HeLa_Curcumin_4h_R1 2 QLLTLSSELSQAR 13 0 E7EQR4;P15311 E7EQR4 EZR Ezrin 0 0 ; ; 205.12 1.15E-19 3775960 836.97 751.83 811.41 870.19 1003.41 1253.81 943.78 968.09 995 753.71 FALSE FALSE TRUE 770.7229413 816.8148351 841.4815684 866.5893844 991.4449911 993.7556726 970.2599267 1263.256184 885.8509894 779.9013664 0.9882313 1.047330945 1.078958962 1.11115254 1.271244075 1.274206862 1.244080301 1.619764035 1.135850029 1 9.607147869 -1 0.323704465 0.980542697 6.824655031 0.822389826 0.075187313 10.07635694 0.128279361 0.01891412 35.48488137 0.1 1 5.844112334 QLMEQDAS(ph)SSPSAQVIGLK ddPTM_HeLa_Curcumin_4h_R1 1 QLMEQDASSSPSAQVIGLK 19 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 0 QLMEQDAS(0.443)S(0.276)S(0.276)PS(0.005)AQVIGLK 92.439 0.0019612 9050100 4612.5 3833 4728.7 5052.8 4625.5 4859.5 3002.1 2089.9 4644.3 4224 TRUE FALSE FALSE 4247.415758 4164.30744 4903.949782 5031.892852 4570.343934 3851.584922 3086.330846 2727.100889 4134.831909 4370.783686 0.971774415 0.952759903 1.121984096 1.151256437 1.045657773 0.881211517 0.706127566 0.623938654 0.94601614 1 12.09367626 -4.835418526 2.333149562 1.009854452 0.637755275 0.823302845 0.066698184 0.1015714 1.071891309 0.010468425 0.047701411 1.46E-05 4.835418526 -0.372099177 QLPFRGDDGIFDDNFIEER ddPTM_HeLa_Curcumin_4h_R1 3 QLPFRGDDGIFDDNFIEER 19 1 O60493-4;O60493;O60493-2 O60493-4 SNX3 Sorting nexin-3 0 0 ;; ;; 130.38 0.00013246 13694600 3199 2268.35 2658.62 2672.31 2231.34 4305.31 3097.13 2677.87 3841.07 3146.92 FALSE FALSE TRUE 2945.795774 2464.416066 2757.150796 2661.252689 2204.732728 3412.340175 3184.027132 3494.340236 3419.714231 3256.275236 0.90465196 0.756820566 0.84671921 0.817268964 0.677071982 1.047927441 0.977812655 1.073109606 1.050192009 1 11.66900693 QLPFRGDEGIFEESFIEER ddPTM_HeLa_Curcumin_4h_R1 1 QLPFRGDEGIFEESFIEER 19 1 A0A087X0R6;Q9UMY4-3;Q9UMY4;Q9UMY4-1 A0A087X0R6 SNX12 Sorting nexin-12 0 0 135.95 1.25E-06 0 797.48 891.16 522.06 722.4 791.43 962.37 646.08 595.05 1023.1 789.09 FALSE FALSE TRUE 734.3586165 968.1878995 541.4080029 719.4109002 781.9927141 762.7636139 664.207266 776.4780057 910.8684897 816.5108188 0.899386266 1.185762487 0.663075112 0.881079446 0.957724866 0.934174534 0.813470257 0.950970872 1.115562058 1 9.673328191 -13.52287875 0.169580418 1.386622749 0.878692208 0.154289703 0.127794086 116.8978125 1.294947842 14.96480413 0.193104732 3.00E-14 13.52287875 -0.507930541 QLPLEPES(ph)PS(ph)GQVGPRPAPPQEESPSSEAK ddPTM_HeLa_Curcumin_4h_R1 1 QLPLEPESPSGQVGPRPAPPQEESPSSEAK 30 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 0 QLPLEPES(0.913)PS(0.747)GQVGPRPAPPQEES(0.27)PS(0.049)S(0.021)EAK 46.145 0.017883 20340000 2787.2 2460.5 2707.2 2895.8 2965.9 4518.4 3584.1 3726.5 3241.9 2971.3 TRUE FALSE FALSE 2566.590179 2673.174656 2807.531213 2883.817947 2930.53358 3581.232907 3684.6602 4862.692695 2886.271681 3074.552454 0.83478497 0.869451634 0.913151184 0.937963489 0.953157776 1.164798116 1.198437904 1.581593669 0.938761567 1 11.5861607 -3.851223138 0.773991586 0.913335204 2.416306401 0.935611746 0.053893164 0.962280502 0.267929219 0.011580929 1.447132375 0.000140856 3.851223138 1.502971197 RLAST(ph)SDIEEK ddPTM_HeLa_Curcumin_4h_R1 1 RLASTSDIEEK 11 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 RLAS(0.361)T(0.52)S(0.119)DIEEK 158.11 0.0038536 9729300 1659.8 1154.4 1599.9 1631.3 1640.2 1966.4 3049 6381.1 1450.8 1595.2 TRUE FALSE FALSE 1528.425079 1254.181192 1659.193701 1624.550113 1620.641686 1558.546474 3134.546734 8326.668015 1291.65087 1650.633081 0.925962951 0.759818282 1.005186265 0.984198203 0.981830368 0.94421134 1.898996676 5.04452995 0.782518468 1 10.68880374 -4.240541384 2.227778107 0.951805175 6.240823862 0.99421429 0.094417554 0.029918462 0.161072644 0.011898423 0.316859673 5.75E-05 4.240541384 5.289018687 up EEEEGISQES(ph)SEEEQ ddPTM_HeLa_Curcumin_4h_R1 2 EEEEGISQESSEEEQ 15 0 P17096;P17096-2 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 1 0 EEEEGISQES(0.923)S(0.077)EEEQ;EEEEGISQES(0.812)S(0.187)EEEQ ; 154.1 0.00039492 11306700 3937.1 3144.3 3437 3201 4287.7 5235.9 4313.7 10699.8 3439.1 2888.8 TRUE FALSE FALSE 3625.474381 3416.079281 3564.378243 3187.75511 4236.571978 4149.915319 4434.730812 13962.11976 3061.839334 2989.185585 1.212863597 1.142812711 1.192424539 1.066429306 1.417299749 1.388309692 1.483591663 4.670877524 1.024305533 1 11.54553675 -4.240519519 3.232468361 1.150972822 5.266059943 0.9831465 0.136201253 0.037209311 0.585362574 0.022130824 0.392055301 5.75E-05 4.240519519 4.11508712 up QLPLEPESPS(ph)GQVGPRPAPPQEESPSSEAK ddPTM_HeLa_Curcumin_4h_R1 1 QLPLEPESPSGQVGPRPAPPQEESPSSEAK 30 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 QLPLEPES(0.121)PS(0.376)GQVGPRPAPPQEES(0.315)PS(0.139)S(0.049)EAK 57.009 0.0011346 53369000 3971.9 2526.2 3423.2 3286.2 3346.7 3917.2 2848.4 3259.7 3888.3 2919.8 TRUE FALSE FALSE 3657.519924 2744.553471 3550.066803 3272.602575 3306.792788 3104.728564 2928.318438 4253.567524 3461.763218 3021.262833 1.210593095 0.908412682 1.175027464 1.083190294 1.094506824 1.027626107 0.969236574 1.407877355 1.145800088 1 11.56093598 -9.71025697 1.609025073 1.000012233 1.115540247 0 0.138309626 0.741230476 3.463450025 0.089606943 0.019696488 1.95E-10 9.71025697 0.115528014 QLPSQK(ac)TVVVEAGKK ddPTM_HeLa_Curcumin_4h_R1 1 QLPSQKTVVVEAGKK 15 2 O94842-3;O94842-2;O94842 O94842-3 TOX4 TOX high mobility group box family member 4 0 1 QLPSQK(1)TVVVEAGKK 121.13 0.00018202 3363200 2448.9 2628.6 2551.3 2239 2381 3413.9 1471.8 1751.9 2895.4 2916 FALSE TRUE FALSE 2255.066981 2855.804471 2645.853422 2229.735611 2352.60813 2705.818657 1513.094747 2286.046245 2577.781864 3017.330783 0.747371483 0.946467151 0.876885437 0.738976192 0.779698449 0.89675904 0.501467971 0.757638592 0.854325246 1 11.55905715 -13.52287875 0.097338748 1.713431295 0.594565024 0.275941668 0.113049398 99.57244904 0.726318552 14.92421725 1.059196632 3.00E-14 13.52287875 -1.118866271 QLQLAQEAAQK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 QLQLAQEAAQKR 12 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 1 ; QLQLAQEAAQK(1)R;QLQLAQEAAQK(1)R 175.74 8.15E-08 5813400 813.3 755.15 835.9 758.06 1243.42 1461.35 1150.47 898.38 1733.12 838.73 FALSE TRUE FALSE 748.9264468 820.4218011 866.8791893 754.9233486 1228.593029 1158.249537 1182.749092 1172.291926 1543.001072 867.8758051 0.862941958 0.945321665 0.998851661 0.86985182 1.415632308 1.334579822 1.362809154 1.350760005 1.77790539 1 9.761344794 -5.760316758 24.99999828 0.935816738 1.363480972 0.103558442 0.270310203 5.46886588 121782.3082 0.008645054 0.016542518 1.74E-06 5.760316758 0.427664234 QLS(ph)ALHR ddPTM_HeLa_Curcumin_4h_R1 1 QLSALHR 7 0 P61313;A0A2R8YEM3;E7EQV9;E7ENU7;E7EX53;A0A2R8Y738;P61313-2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 1 0 QLS(1)ALHR 76.282 0.0088716 0 1581.6 1245 1246.8 1490.9 1616.1 1235.9 1118 1268 1734.8 1216.7 TRUE FALSE FALSE 1456.414691 1352.612252 1293.007505 1484.731051 1596.829063 979.5604085 1149.368071 1654.607363 1544.49678 1258.980234 1.156820934 1.074371317 1.027027645 1.179312439 1.268351178 0.778058608 0.912935755 1.314244114 1.226783978 1 10.29803992 -4.235194327 23.29828153 1.064501152 1.314244949 0.211723195 0.141519829 3917.759321 3477739.459 0.018808556 1.736154614 5.82E-05 4.235194327 0.249743798 QLS(ph)EEQPSGNGVK ddPTM_HeLa_Curcumin_4h_R1 1 QLSEEQPSGNGVK 13 0 Q9H4Z3 Q9H4Z3 PCIF1 Phosphorylated CTD-interacting factor 1 1 0 QLS(1)EEQPSGNGVK 106.3 0.005552 0 3283.1 3002 3851.1 3676.2 3465.7 3757.3 2636 2924.4 4027.8 3823.2 TRUE FALSE FALSE 3023.239171 3261.479503 3993.825154 3660.988858 3424.373791 2977.993627 2709.959066 3816.036098 3585.960417 3956.055915 0.764205369 0.824427049 1.009547195 0.925413831 0.86560298 0.752768335 0.68501536 0.964606209 0.906448365 1 11.9498471 -9.510408831 1.250532688 1.000339112 0.838428462 0.121036125 0.098763359 0.511177076 1.426165845 0.070731806 0.01692248 3.09E-10 9.510408831 -0.16191065 GGTTSWGTSGQPS(ph)PSYDSSR ddPTM_HeLa_Curcumin_4h_R1 4 GGTTSWGTSGQPSPSYDSSR 20 0 Q99081;Q99081-3;H0YNQ5 Q99081 TCF12 Transcription factor 12 1 0 GGTTSWGTS(0.008)GQPS(0.873)PS(0.103)YDS(0.014)SR;GGTTSWGTS(0.06)GQPS(0.932)PS(0.007)YDSSR;GGTTSWGTS(0.031)GQPS(0.968)PSYDSSR;GGTTSWGT(0.001)S(0.123)GQPS(0.873)PS(0.002)YDSSR ;;; 215.64 1.26E-18 93021000 5378.71 4522.09 4824.94 5118.69 4776.88 6258.22 5657.81 7803.49 5552.25 4715.89 TRUE FALSE FALSE 4952.979428 4912.95931 5003.756521 5097.510217 4719.918826 4960.194627 5816.552921 10182.73818 4943.182066 4879.766826 1.015003299 1.006802063 1.025408938 1.044621679 0.967242697 1.016481894 1.191973536 2.086726383 1.012995547 1 12.2525965 -4.240495065 2.622331893 1.009077676 2.340787892 0.996151952 0.019959774 0.022839375 0.193025705 0.003040652 0.067971811 5.75E-05 4.240495065 1.331710216 up DQTPAPKT(ph)PNR ddPTM_HeLa_Curcumin_4h_R1 1 DQTPAPKTPNR 11 1 Q9BYW2 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 0 DQTPAPKT(1)PNR 91.712 0.013222 14453000 6692.7 5575.5 5155.6 6632.4 6005.6 8180 5145.5 1833.2 7861 5459.4 TRUE FALSE FALSE 6162.965733 6057.421376 5346.671071 6604.956886 5933.987142 6483.375792 5289.868882 2392.134241 6998.667967 5649.113744 1.090961523 1.072278175 0.946461926 1.169202318 1.050427981 1.147680165 0.936406863 0.423453014 1.238896628 1 12.46380883 -4.281968201 3.220722826 1.054152591 0.347501986 0.841521442 0.085594239 0.066944705 1.109930587 0.008762135 0.114785116 5.22E-05 4.281968201 -0.706650604 down QLS(ph)LEGSGLGVEDLKDNTPSGK ddPTM_HeLa_Curcumin_4h_R1 2 QLSLEGSGLGVEDLKDNTPSGK 22 1 Q9UMZ2-6;Q9UMZ2-9;Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2 Q9UMZ2-6 SYNRG Synergin gamma 1 0 QLS(0.971)LEGS(0.029)GLGVEDLKDNTPSGK;QLS(0.997)LEGS(0.003)GLGVEDLKDNTPSGK ; 142.14 1.07E-05 135237000 4637.7 2916.5 3857.5 4407.1 3924.8 5629.2 5508.1 5931.3 3696.7 3849.2 TRUE FALSE FALSE 4270.621151 3168.589264 4000.462343 4388.864588 3877.999323 4461.640466 5662.642462 7739.726066 3291.181259 3982.959413 1.072223116 0.795536418 1.004394453 1.101910447 0.973647713 1.120182257 1.42171734 1.943209875 0.82631554 1 11.95962506 -4.315283142 1.463980194 1.014359355 2.257774158 0.903327906 0.098894445 0.191074798 0.395568026 0.011884007 0.334145925 4.84E-05 4.315283142 1.243414804 QLS(ph)LPLTQSK ddPTM_HeLa_Curcumin_4h_R1 1 QLSLPLTQSK 10 0 Q9C0I1-3;Q9C0I1-2;Q9C0I1 Q9C0I1-3 MTMR12 Myotubularin-related protein 12 1 0 QLS(0.915)LPLT(0.084)QSK 99.161 0.013134 121820000 3545.3 2210.5 2860.8 2878.5 2723.5 3359.9 2516.4 1967.2 2599 2630.3 TRUE FALSE FALSE 3264.685764 2401.56577 2966.823765 2866.58953 2691.024041 2663.018866 2587.003411 2566.990224 2313.896202 2721.702729 1.199501227 0.882376221 1.090061649 1.053233881 0.988728127 0.978438548 0.950509173 0.943155987 0.850164927 1 11.41029379 -5.675408984 0.779578609 1.082753257 0.938122679 0 0.10628367 0.856545347 0.914197398 0.017241275 0.071310866 2.11E-06 5.675408984 -0.144630578 QLS(ph)MSSADSADAK ddPTM_HeLa_Curcumin_4h_R1 1 QLSMSSADSADAK 13 0 Q5JSZ5;Q5JSZ5-5 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 QLS(0.805)MS(0.15)S(0.044)ADSADAK 97.767 0.009547 5996000 3117.4 2383.2 3343.8 2857 3335.5 2740.4 2250.9 3483.4 3020.3 2527.3 TRUE FALSE FALSE 2870.654501 2589.193189 3467.72417 2845.178491 3295.726341 2172.010149 2314.054196 4545.472624 2688.980646 2615.123487 1.097712791 0.990084484 1.32602693 1.087970991 1.260256488 0.830557394 0.884873777 1.738148369 1.028242322 1 11.35266336 -4.252435702 24.83270144 1.056550612 1.738148756 0.670425967 0.143442716 492.4835898 1358268.657 0.019414596 0.317394257 5.59E-05 4.252435702 0.681598144 QLS(ph)PEDSSSPVK ddPTM_HeLa_Curcumin_4h_R1 1 QLSPEDSSSPVK 12 0 Q96AY2;Q96AY2-2 Q96AY2 EME1 Crossover junction endonuclease EME1 1 0 QLS(0.941)PEDS(0.054)S(0.005)SPVK 124.42 0.0031138 17716000 4451.8 3266.1 3786.5 3700.6 4000.7 4464.3 2748.4 2359.1 4813.9 3657.9 TRUE FALSE FALSE 4099.435332 3548.407131 3926.831021 3685.287898 3952.994265 3538.353857 2825.512707 3078.37873 4285.827214 3785.011753 1.083070701 0.937489065 1.037468647 0.97365296 1.044380975 0.934832991 0.746500379 0.813307575 1.132315431 1 11.88608206 -4.940735558 3.385828551 1.026921678 0.780053563 0.769489838 0.054090532 0.070009935 1.625095466 0.00671432 0.022635942 1.15E-05 4.940735558 -0.246868115 QLS(ph)S(ph)ELGDLEKHSSLPALK ddPTM_HeLa_Curcumin_4h_R1 1 QLSSELGDLEKHSSLPALK 19 1 Q99801-3;Q99801-4;Q99801-2;Q99801-5;Q99801 Q99801-3 NKX3-1 Homeobox protein Nkx-3.1 2 0 QLS(1)S(1)ELGDLEKHSSLPALK 72.184 0.0034231 0 767.41 449.43 663.43 456.43 537.03 601.73 593.54 575.31 672.9 466.83 TRUE FALSE FALSE 706.6686887 488.2767266 688.0172994 454.5414136 530.626268 476.9244151 610.193135 750.7193706 599.0845535 483.0523078 1.46292374 1.010815431 1.424312209 0.940977626 1.098486146 0.987314226 1.263203022 1.554116104 1.240206379 1 8.916035611 -4.307797537 3.849857561 1.18066724 1.575105506 0.316043801 0.175211745 0.257939311 7.048656668 0.028881429 0.25907272 4.92E-05 4.307797537 0.394438266 VLS(ph)PTAAKPSPFEGK ddPTM_HeLa_Curcumin_4h_R1 1 VLSPTAAKPSPFEGK 15 1 Q96QC0 Q96QC0 PPP1R10 Serine/threonine-protein phosphatase 1 regulatory subunit 10 1 0 VLS(0.496)PT(0.496)AAKPS(0.009)PFEGK 69.081 0.013509 675860000 5985.9 4566.5 4835 5106.2 5134.5 6717.3 7795.5 12050 5222 4831.8 TRUE FALSE FALSE 5512.109699 4961.207912 5014.189353 5085.071897 5073.274441 5324.05626 8014.220749 15723.98953 4649.159665 4999.70469 1.102487055 0.99230019 1.002897104 1.01707445 1.014714819 1.064874146 1.602938823 3.144983655 0.929886854 1 12.28762717 -4.240047806 2.012696265 1.035820999 3.839401931 0.994094963 0.049561648 0.040066655 0.164550524 0.007107484 0.209614024 5.75E-05 4.240047806 2.803580932 up QLS(ph)SSSSYSGDISR ddPTM_HeLa_Curcumin_4h_R1 1 QLSSSSSYSGDISR 14 0 A0A0A0MS99;I3L4X2;P33527-8;P33527-6;P33527-7;P33527-5;P33527-4;P33527-2;P33527-3;P33527;P33527-9 A0A0A0MS99 ABCC1 Multidrug resistance-associated protein 1 1 0 QLS(0.434)S(0.434)S(0.051)S(0.021)S(0.021)YS(0.038)GDISR 181.69 0.00010735 10579000 524.23 521.54 729.93 913.12 490.92 886.05 348.05 108.62 1089.1 677.96 TRUE FALSE FALSE 482.7366423 566.6195937 756.9818479 909.3417514 485.0660996 702.2732422 357.8153463 141.737738 969.6284548 701.5190595 0.688130473 0.807703776 1.079060986 1.296246679 0.691451063 1.001075071 0.510057911 0.20204403 1.38218405 1 9.454338491 -4.544614994 3.180393624 0.890805779 0.227333059 0.5194996 0.236718103 0.140416255 2.739739649 0.028012632 0.164618382 2.85E-05 4.544614994 -0.66347272 QLSES(ph)FK ddPTM_HeLa_Curcumin_4h_R1 1 QLSESFK 7 0 Q08945 Q08945 SSRP1 FACT complex subunit SSRP1 1 0 QLS(0.001)ES(0.999)FK 107.21 0.016795 35015000 5708.1 5929.1 5332.7 5573 6089.4 8499 8055.4 2610.2 5578.3 4666.1 TRUE FALSE FALSE 5256.297862 6441.584984 5530.334553 5549.940403 6016.787882 6736.211597 8281.412844 3406.037964 4966.374446 4828.246628 1.088655627 1.334145805 1.145412606 1.149473262 1.246164156 1.395167256 1.715200876 0.70543993 1.028608277 1 12.23728366 -7.391500777 0.62100814 1.00877648 1.286810495 0.112136196 0.240576279 0.84504017 0.72471327 0.072410315 0.078016489 4.06E-08 7.391500777 0.278034015 KASSPS(ph)PLTIGTPESQR ddPTM_HeLa_Curcumin_4h_R1 1 KASSPSPLTIGTPESQR 17 1 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 0 KAS(0.008)S(0.011)PS(0.705)PLT(0.26)IGT(0.015)PESQR 59.537 0.016767 69570000 2257.3 1880.1 2179.7 2144.6 2206.3 2626.3 1620.6 582.69 2793.1 2071.8 TRUE FALSE FALSE 2078.632323 2042.607466 2260.481599 2135.726213 2179.991313 2081.575775 1666.069674 760.3494986 2486.703918 2143.794896 0.969604101 0.952799855 1.054429976 0.996236262 1.016884273 0.970977111 0.777159083 0.354674554 1.159954212 1 11.06595117 -4.281494147 1.857867811 0.991438486 0.166290573 0.919702687 0.059648855 0.075534638 0.272148718 0.004086123 0.10634681 5.23E-05 4.281494147 -0.825147912 down QLSLAAT(ph)AS(ph)PPQAPSPNR ddPTM_HeLa_Curcumin_4h_R1 5 QLSLAATASPPQAPSPNR 18 0 Q8NEQ6 Q8NEQ6 C1orf64 Uncharacterized protein C1orf64 2 0 QLS(0.473)LAAT(0.827)AS(0.701)PPQAPSPNR;QLS(0.463)LAAT(0.833)AS(0.704)PPQAPSPNR;QLS(0.292)LAAT(0.898)AS(0.81)PPQAPSPNR;QLS(0.22)LAAT(0.921)AS(0.859)PPQAPSPNR;QLS(0.008)LAAT(0.997)AS(0.995)PPQAPSPNR ;;;; 113.01 0.0026666 192024700 8652.82 7081.95 7097.21 7180.74 7087.74 9243.19 6863.99 5730 8919 7270.28 TRUE FALSE FALSE 7967.940167 7694.082201 7360.238846 7151.028001 7003.22333 7326.048202 7056.575086 7477.050622 7940.608014 7522.921689 1.059155006 1.022751867 0.978375045 0.950565259 0.930918016 0.973830183 0.938009909 0.993902493 1.055521823 1 12.87707736 -6.662370592 3.110953318 1.028570252 0.956273978 0.715548654 0.022882622 0.123904896 2.409254141 0.004298885 0.006190865 2.18E-07 6.662370592 -0.072296274 QLSLPLT(ph)QSK ddPTM_HeLa_Curcumin_4h_R1 1 QLSLPLTQSK 10 0 Q9C0I1-3;Q9C0I1-2;Q9C0I1 Q9C0I1-3 MTMR12 Myotubularin-related protein 12 1 0 QLS(0.275)LPLT(0.722)QS(0.003)K 130.69 0.0081833 115530000 4370.1 3295.3 3494.6 3970 3608.8 3554.1 3615.4 2409 3905.4 2995.4 TRUE FALSE FALSE 4024.201974 3580.131048 3624.11295 3953.573192 3565.767417 2816.939597 3716.838394 3143.49301 3476.987391 3099.489927 1.298343298 1.155071038 1.169261083 1.275556071 1.150436846 0.908839733 1.199177439 1.014196879 1.121793415 1 11.5978151 -5.479046825 24.89951044 1.158403422 1.052091312 0.240288022 0.101715374 731.8928968 415764.1363 0.018558526 0.041496052 3.32E-06 5.479046825 -0.10631211 QLSPEDSS(ph)SPVK ddPTM_HeLa_Curcumin_4h_R1 1 QLSPEDSSSPVK 12 0 Q96AY2;Q96AY2-2 Q96AY2 EME1 Crossover junction endonuclease EME1 1 0 QLSPEDSS(0.992)S(0.008)PVK 246.31 9.09E-27 12839000 6368.6 5722.8 6509.1 6120.2 7729.5 7753.4 6252.8 1941.7 5573.8 4860.8 TRUE FALSE FALSE 5864.51859 6217.453332 6750.332972 6094.876234 7637.330761 6145.257441 6428.236739 2533.715392 4962.368085 5029.712438 1.165974926 1.236144891 1.342091234 1.211774293 1.518442824 1.22179101 1.278052536 0.503749553 0.986610695 1 12.2962602 -8.573955278 0.876339106 1.01520933 1.207623669 0.078629595 0.248904113 1.005484536 1.57452811 0.099980599 0.05026346 2.67E-09 8.573955278 0.192414339 QLSPEDSSS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 1 QLSPEDSSSPVK 12 0 Q96AY2;Q96AY2-2 Q96AY2 EME1 Crossover junction endonuclease EME1 1 0 QLSPEDSS(0.257)S(0.743)PVK 183.28 6.49E-05 36667000 4034.2 3181 3659.4 2978.4 4383.9 4242.7 3821.4 1245 3291.6 2381.3 TRUE FALSE FALSE 3714.888813 3455.951466 3795.020583 2966.07617 4331.624856 3362.716195 3928.618199 1624.594769 2930.519715 2464.049998 1.507635323 1.402549246 1.540155673 1.203740254 1.757928962 1.364711024 1.594374385 0.659318914 1.189310167 1 11.26681581 -9.352519729 1.025017065 0.995090477 1.405657686 0.119348212 0.286030292 0.615924881 1.13616063 0.186651857 0.046412614 4.44E-10 9.352519729 0.410567209 ANSTSDS(ph)VFTET(ph)PSPVLK ddPTM_HeLa_Curcumin_4h_R1 1 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 2 0 ANS(0.274)T(0.042)S(0.302)DS(0.344)VFT(0.038)ET(0.529)PS(0.471)PVLK 122.13 0.001431 9435600 1652.3 808.73 1443.6 1374.8 1138.5 2141.6 3892.4 13881 0 1538.1 TRUE FALSE FALSE 1521.518712 878.6330176 1497.101086 1369.111442 1124.924131 1697.408019 4001.610268 18113.253 0 1591.548861 0.955998744 0.552061604 0.940656692 0.860238398 0.706810931 1.066513295 2.514286785 11.38089659 0 1 10.63621573 -4.23992162 2.745684345 0.92566257 13.69481858 0.988993494 0.334103013 0.019594879 0.188713836 0.027048018 0.57665066 5.76E-05 4.23992162 12.76915601 up QLSSSSSYS(ph)GDISR ddPTM_HeLa_Curcumin_4h_R1 1 QLSSSSSYSGDISR 14 0 A0A0A0MS99;I3L4X2;P33527-8;P33527-6;P33527-7;P33527-5;P33527-4;P33527-2;P33527-3;P33527;P33527-9 A0A0A0MS99 ABCC1 Multidrug resistance-associated protein 1 1 0 QLS(0.014)S(0.074)S(0.137)S(0.223)S(0.223)Y(0.06)S(0.261)GDIS(0.008)R 92.269 0.008689 12192000 914.45 705.56 963.89 1652.4 889.95 1386.7 528.05 416.32 1786.9 1045 TRUE FALSE FALSE 842.0703176 766.5454625 999.6126113 1645.562807 879.3379275 1099.082789 542.8656618 543.2540515 1590.881541 1081.313672 0.778747499 0.708902035 0.924442775 1.521818182 0.813212623 1.016432897 0.502042724 0.502401907 1.471248891 1 10.07856937 -4.754038736 24.85704939 0.927504576 0.502222047 0.326762379 0.272950227 124.098606 416806.6994 0.030446463 0.109436992 1.76E-05 4.754038736 -0.425282529 QLSSTSPLAPY(ph)PTSQMVSSDR ddPTM_HeLa_Curcumin_4h_R1 1 QLSSTSPLAPYPTSQMVSSDR 21 0 Q6UUV7;Q6UUV7-3 Q6UUV7 CRTC3 CREB-regulated transcription coactivator 3 1 0 QLSST(0.001)S(0.01)PLAPY(0.926)PT(0.049)S(0.014)QMVSSDR 121.42 0.00012556 0 1255.7 1084.6 1213.4 1350.4 1319.6 1286.5 1250.2 603.44 1463.7 1467 TRUE FALSE FALSE 1156.31002 1178.347991 1258.369671 1344.812403 1303.864632 1019.665398 1285.277247 787.4260781 1303.135772 1517.978141 0.761743525 0.776261502 0.828977465 0.885923431 0.858948226 0.671726009 0.846703396 0.518733476 0.858468075 1 10.5679353 -13.52287875 0.173931005 1.929177642 0.712355796 0.276409419 0.105864243 39.08375581 0.439652063 12.37817776 0.145202682 3.00E-14 13.52287875 -1.216821847 QLT(ph)QPETHFGR ddPTM_HeLa_Curcumin_4h_R1 2 QLTQPETHFGR 11 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3;H0Y5J4;Q9UJU6-5;Q9UJU6 B4DDD6;H0Y5J4 DBNL Drebrin-like protein 1 0 QLT(1)QPETHFGR;QLT(0.923)QPET(0.077)HFGR ; 118.73 0.0041466 18582000 4476.1 3038.6 2862.1 3173.6 4478.4 13013.4 26090 6028.5 4476 2776.2 TRUE FALSE FALSE 4121.811962 3301.243044 2968.171944 3160.468484 4424.998005 10314.27415 26822.01518 7866.561898 3984.993998 2872.672743 1.434835197 1.149188696 1.033244024 1.100183963 1.540376646 3.590480041 9.336954669 2.738412134 1.387207787 1 11.48817793 -5.050632071 3.906860067 1.217015772 6.148219123 0.61765681 1.507299043 0.085131568 2.661588799 0.18268638 0.528868857 8.90E-06 5.050632071 4.931203351 QLVAGNS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 QLVAGNSPK 9 0 Q96EU6-2;Q96EU6 Q96EU6-2 RRP36 Ribosomal RNA processing protein 36 homolog 1 0 QLVAGNS(1)PK;QLVAGNS(1)PK ; 114.87 0.0075781 115325000 17068.3 14444.6 15541.1 17049.8 16229.4 20800 17233.9 12439.8 17471.3 15263.9 TRUE FALSE FALSE 15717.32604 15693.12686 16117.06684 16979.25245 16035.875 16485.84554 17717.43685 16232.63775 15554.7421 15794.31939 0.995125251 0.993593106 1.020434401 1.075022736 1.015293829 1.043783219 1.121760072 1.027751646 0.984831427 1 13.94711815 -6.480215333 3.816741045 0.997478965 1.057193809 0.541345438 0.027410653 0.133926006 4.069738273 0.004077688 0.006195802 3.31E-07 6.480215333 0.059714844 QLVAGNS(ph)PKK ddPTM_HeLa_Curcumin_4h_R1 1 QLVAGNSPKK 10 1 Q96EU6-2;Q96EU6 Q96EU6-2 RRP36 Ribosomal RNA processing protein 36 homolog 1 0 QLVAGNS(1)PKK 101.89 0.017836 59356000 3128.9 2183.1 2555.8 2196.4 2373.7 3297 3338 1838.6 3222 2578.8 TRUE FALSE FALSE 2881.244263 2371.797436 2650.520196 2187.311879 2345.395178 2613.165035 3431.655296 2399.180676 2868.554661 2668.413108 1.079759448 0.888841922 0.99329455 0.819705117 0.878947555 0.979295532 1.286028496 0.899103916 1.075003961 1 11.38176632 QLVHELDEAEYR ddPTM_HeLa_Curcumin_4h_R1 4 QLVHELDEAEYR 12 0 H0YKK6;Q06323-3;Q06323;Q06323-2 H0YKK6 PSME1 Proteasome activator complex subunit 1 0 0 ;;; ;;; 198.52 9.70E-07 17314200 8123.6 6586.7 6853.8 7496.5 7266.7 8451.9 6886 6071.1 8319.4 6818.4 FALSE FALSE TRUE 7480.608488 7156.024998 7107.807857 7465.481469 7180.049349 6698.880667 7079.202627 7922.150442 7406.782634 7055.338892 1.060276282 1.01427091 1.007436775 1.058132229 1.017676041 0.94947681 1.003382365 1.122858953 1.049812454 1 12.78449967 -5.560997019 24.96305259 1.028440171 1.016473981 0 0.044475227 774.4053079 507142.4102 0.006626413 0.013252827 2.75E-06 5.560997019 -0.01196619 QLVNNKDTTS(ph)FEDISPQGVSDDSSTGSR ddPTM_HeLa_Curcumin_4h_R1 2 QLVNNKDTTSFEDISPQGVSDDSSTGSR 28 1 Q3V6T2;Q3V6T2-3;Q3V6T2-2;Q3V6T2-4;Q3V6T2-5;A0A2U3TZV9;A0A2R8Y7B1;A0A2R8Y7D4;H7C2C6;A0A2R8Y820;A0A2R8Y885;A0A2R8YCU9;A0A2R8YDS8;H0Y470;H0Y7U8;A0A2R8Y5D7;A0A2R8Y802 Q3V6T2 CCDC88A Girdin 1 0 QLVNNKDT(0.074)T(0.188)S(0.738)FEDISPQGVSDDSSTGSR;QLVNNKDT(0.034)T(0.163)S(0.803)FEDISPQGVSDDSSTGSR ; 119.2 7.21E-11 29822000 2562.7 1723.34 1997.67 2653.23 2346.34 3154.2 2480.41 593.62 2873.9 2308.71 TRUE FALSE FALSE 2359.859591 1872.297831 2071.705408 2642.251637 2318.361428 2499.983365 2550.003629 774.6120053 2558.64036 2388.937501 0.987828099 0.783736632 0.867207873 1.106036318 0.970457129 1.046483369 1.067421658 0.32424959 1.071036961 1 11.2221534 -4.257061209 24.99784518 0.984647604 0.324249327 0.819600458 0.093529708 132.9584018 759118.4745 0.012431294 0.131426952 5.53E-05 4.257061209 -0.660398276 SIQPQVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 SIQPQVSPR 9 0 A0A2R8YCL1;Q13322-3;Q13322-2;Q13322-4;Q13322 A0A2R8YCL1 GRB10 Growth factor receptor-bound protein 10 1 0 SIQPQVS(1)PR;SIQPQVS(1)PR ; 149.94 0.0017023 248586000 7419.5 6061.6 6570.4 5976.4 6331 7458.2 4673.9 1284.51 7626.2 6239.7 TRUE FALSE FALSE 6832.238746 6585.537694 6813.904804 5951.67124 6255.50696 5911.285249 4805.037055 1676.151186 6789.62494 6456.529111 1.058190652 1.019981105 1.055351054 0.921806614 0.968865292 0.915551552 0.744213644 0.259605611 1.051590541 1 12.6565431 -4.280428153 1.378604946 1.018808087 6.12E-23 0.967095988 0.042010198 0.156264952 0.264099274 0.006525979 0.218454705 5.24E-05 4.280428153 -1.018808087 down QLWDS(ph)PETAPAAR ddPTM_HeLa_Curcumin_4h_R1 1 QLWDSPETAPAAR 13 0 Q9Y613 Q9Y613 FHOD1 FH1/FH2 domain-containing protein 1 1 0 QLWDS(0.999)PET(0.001)APAAR 151.07 0.00050597 11257000 1838.5 1532.5 1683.5 1755.2 1661.5 2198.5 1239.3 881.92 1940.7 1374.7 TRUE FALSE FALSE 1692.980785 1664.962471 1745.891991 1747.937447 1641.687698 1742.506318 1274.071423 1150.813348 1727.810065 1422.470723 1.19016916 1.170472225 1.227365852 1.228803813 1.154110008 1.224985717 0.895674971 0.809024277 1.214654219 1 10.47418324 -4.635972883 5.28900081 1.128634829 0.830335899 0.716153522 0.077699213 0.107004451 4.407552742 0.013981978 0.055269205 2.31E-05 4.635972883 -0.29829893 QLWGLLIEETEKR ddPTM_HeLa_Curcumin_4h_R1 1 QLWGLLIEETEKR 13 1 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 98.253 0.011631 8700800 1898.4 1458.2 1389.6 1277.4 1161 2225.6 1439.2 1219.1 2023.5 1596.6 FALSE FALSE TRUE 1748.139637 1584.24031 1441.099798 1272.114457 1147.155833 1763.985472 1479.580079 1590.797978 1801.527113 1652.081731 1.058143555 0.958935796 0.872293284 0.770006976 0.694369904 1.067734991 0.895585279 0.962905132 1.090458831 1 10.69006935 -6.950579239 3.411225115 1.027135005 0.873752055 0.380049935 0.097422859 0.204661609 4.932352219 0.016320944 0.021478907 1.12E-07 6.950579239 -0.15338295 QLYK(ac)IVPIK(ac)DIR ddPTM_HeLa_Curcumin_4h_R1 1 QLYKIVPIKDIR 12 2 A0A3B3ISG5;P14735 A0A3B3ISG5 IDE Insulin-degrading enzyme 0 2 QLYK(1)IVPIK(1)DIR 42.976 0.01831 1053200 1443.1 921.28 1164.1 821.4 1867.4 1933.7 1257.1 1315.9 1492.1 1570.3 FALSE TRUE FALSE 1328.877112 1000.911338 1207.24257 818.0012644 1845.132475 1532.628823 1292.370843 1717.111852 1328.420363 1624.867808 0.817837061 0.615995549 0.742978945 0.503426347 1.135558515 0.94323293 0.795369836 1.056770184 0.817555961 1 10.66610664 -4.247130347 22.8583409 0.864532432 1.056770627 0.093146201 0.177232765 1542.776597 2464405.345 0.025859753 0.655648244 5.66E-05 4.247130347 0.192238195 QMADTGK(ac)LNTLLQR ddPTM_HeLa_Curcumin_4h_R1 1 QMADTGKLNTLLQR 14 1 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PRZ7;A0A1W2PQD4;A0A1W2PQ74;A0A1W2PPE9 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 1 QMADTGK(1)LNTLLQR 208.28 3.86E-19 1285400 807.47 507.26 599.19 522.65 469.5 527.14 510.86 565.89 530.18 646.87 FALSE TRUE FALSE 743.5578975 551.1052941 621.3965085 520.4874128 463.9015191 417.8052219 525.1933567 738.427256 472.0205804 669.3486844 1.110867796 0.8233456 0.928359946 0.777602802 0.693064064 0.624196673 0.784633434 1.10320267 0.705193857 1 9.386614141 -7.247847222 19.90963836 1.052354207 0.808117907 0 0.166432349 36.65897152 53696.81628 0.021700041 0.026436559 5.65E-08 7.247847222 -0.244236299 QMDTVLSSS(ph)PDVLFDPINGLTPDEEALSNER ddPTM_HeLa_Curcumin_4h_R1 1 QMDTVLSSSPDVLFDPINGLTPDEEALSNER 31 0 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 0 QMDTVLS(0.003)S(0.096)S(0.901)PDVLFDPINGLTPDEEALSNER 84.221 1.39E-06 678190 176.03 116.14 0 119.82 171.9 198.66 142.3 68.993 0 67.065 TRUE FALSE FALSE 162.0970398 126.1786241 0 119.3242166 169.8502048 157.4556766 146.292555 90.0286481 0 69.39550376 2.335843549 1.818253594 0 1.719480516 2.447567862 2.268960784 2.108098466 1.297326818 0 1 6.116770286 -9.603678406 1.412512785 1.001295785 1.827953927 0.248395209 0.750708621 0.651448223 2.338480949 0.505017075 0.117360295 2.49E-10 9.603678406 0.826658142 QMEQISQFLQAAER ddPTM_HeLa_Curcumin_4h_R1 4 QMEQISQFLQAAER 14 0 P37802;P37802-2;X6RJP6 P37802 TAGLN2 Transgelin-2 0 0 ;;; ;;; 270.93 9.72E-50 235896000 4247.57 2594.93 3389.27 3058.9 3559.53 5107.42 3106.84 3209.49 3748.24 3223.2 FALSE FALSE TRUE 3911.370352 2819.224186 3514.879328 3046.243082 3517.08493 4048.08352 3194.009569 4188.048726 3337.06745 3335.20596 1.172752268 0.845292381 1.053871746 0.91335981 1.054533055 1.213743189 0.957664866 1.255709176 1.000558133 1 11.70356014 -4.241946146 23.63231803 1.055095605 1.255709567 0.250038148 0.10891419 2550.078701 3091446.41 0.015560721 0.720971589 5.73E-05 4.241946146 0.200613962 QMEQVAQFLK ddPTM_HeLa_Curcumin_4h_R1 1 QMEQVAQFLK 10 0 Q01995;H0YCU9 Q01995 TAGLN Transgelin 0 0 94.692 0.016245 578050 257.25 282.33 436.77 693.65 354.23 360.46 260.61 192.32 214.29 161.45 FALSE FALSE TRUE 236.8883911 306.7333472 452.9570804 690.7798601 350.0060386 285.6965328 267.9220152 250.9574827 190.7829231 167.0603755 1.417980717 1.836062838 2.711337617 4.134911454 2.095087106 1.710139415 1.603743643 1.502196328 1.141999846 1 7.384225776 -7.214283675 2.346570537 1.177064772 2.303182758 0.321496703 0.717711753 0.280958803 2.958799551 0.139762718 0.1685982 6.11E-08 7.214283675 1.126117985 QMGVTEWSVNGS(ph)PIDTLR ddPTM_HeLa_Curcumin_4h_R1 1 QMGVTEWSVNGSPIDTLR 18 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 0 QMGVT(0.001)EWS(0.016)VNGS(0.983)PIDTLR 110.44 0.00085482 6618300 1197.1 874.56 789.79 1136.7 759.3 1609.4 1386 746.74 1130.5 831.5 TRUE FALSE FALSE 1102.348272 950.1530694 819.0603122 1131.996637 750.2458434 1275.592298 1424.88743 974.4175884 1006.486978 860.3945631 1.281212503 1.104322494 0.951958958 1.315671536 0.871978829 1.482566665 1.656086046 1.132524112 1.169797 1 9.748854598 -5.234625565 24.69592757 1.118568715 1.446961732 0.407998487 0.177376857 485.4262222 447083.9642 0.024921823 0.063518693 5.83E-06 5.234625565 0.328393017 QMGVTEWYVNGS(ph)PIDTLR ddPTM_HeLa_Curcumin_4h_R1 1 QMGVTEWYVNGSPIDTLR 18 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 0 QMGVT(0.005)EWY(0.036)VNGS(0.958)PIDTLR 88.781 0.0038391 5485200 1128.9 1101.8 1143.8 957.6 1037.7 1581.9 1361.7 762.87 1136 726.75 TRUE FALSE FALSE 1039.546374 1197.034682 1186.190234 953.6377049 1025.326105 1253.796108 1399.905637 995.4655512 1011.383642 752.0045084 1.382367209 1.591791896 1.577371174 1.268127643 1.363457391 1.667272063 1.861565485 1.323749446 1.344916993 1 9.554597501 -9.090501064 0.302398616 0.778601672 1.597681784 0.231825026 0.201035277 1.868923852 0.253382089 0.548566685 0.108707992 8.12E-10 9.090501064 0.819080111 QMGYTEAIEVIQAAS(ph)SPVK ddPTM_HeLa_Curcumin_4h_R1 1 QMGYTEAIEVIQAASSPVK 19 0 P19838-3;P19838;P19838-2 P19838-3 NFKB1 Nuclear factor NF-kappa-B p105 subunit;Nuclear factor NF-kappa-B p50 subunit 1 0 QMGYTEAIEVIQAAS(0.5)S(0.5)PVK 65.092 0.014489 8509900 743.92 511 654.44 657.25 556.99 813.13 662.43 718.1 573.55 673.81 TRUE FALSE FALSE 685.037947 555.168563 678.6941221 654.5304736 550.348258 644.4776721 681.016003 937.0453843 510.633 697.2248473 0.982520846 0.796254702 0.973422167 0.938765272 0.789341143 0.924346966 0.976752343 1.343964415 0.732379234 1 9.445480174 -4.262383444 4.862756763 0.954308493 1.364563882 0.588862928 0.102880749 0.080369583 5.561551243 0.011498332 0.110879413 5.47E-05 4.262383444 0.410255389 QMNLGFGDES(ph)PEPEASGR ddPTM_HeLa_Curcumin_4h_R1 1 QMNLGFGDESPEPEASGR 18 0 Q9P227-2;Q9P227 Q9P227-2 ARHGAP23 Rho GTPase-activating protein 23 1 0 QMNLGFGDES(0.857)PEPEAS(0.143)GR 118.15 0.00047671 3014100 1344.3 1049.5 1058.9 1302.2 1259.7 1586.2 904.11 392.91 1186.2 879.88 TRUE FALSE FALSE 1237.897237 1140.214104 1098.143766 1296.811841 1244.6789 1257.20424 929.4768933 512.7064503 1056.076828 910.4557645 1.359645668 1.252355302 1.206147304 1.424354584 1.367094316 1.380851535 1.020891876 0.563131643 1.159943041 1 9.830445114 -4.348349574 3.056800755 1.225027703 0.517233708 0.733995767 0.127534726 0.165237117 2.409722625 0.023999575 0.249254437 4.48E-05 4.348349574 -0.707793996 QMNMS(ph)PPPGNAGPVIMSIEEK ddPTM_HeLa_Curcumin_4h_R1 2 QMNMSPPPGNAGPVIMSIEEK 21 0 Q86U42-2;Q86U42;B4DEH8;G3V4T2;Q92843-2 Q86U42-2 PABPN1 Polyadenylate-binding protein 2 1 0 QMNMS(0.997)PPPGNAGPVIMS(0.003)IEEK;QMNMS(1)PPPGNAGPVIMSIEEK ; 87.237 0.0011368 10728000 5232.2 3552.2 3743.4 4294.3 3308.6 5253 3497.2 2146.1 5143.3 4123.5 TRUE FALSE FALSE 4818.065849 3859.23634 3882.133697 4276.531324 3269.147106 4163.468586 3595.32202 2800.436011 4579.092858 4266.791318 1.129201194 0.904482093 0.909848504 1.002282747 0.766183969 0.975784442 0.842628981 0.656333015 1.073193535 1 12.05893584 -3.040004572 0.324969099 1.059422204 4.40E-11 0.59350223 0.086170432 7.657679184 0.312378823 0.033681278 3.764358471 0.000912001 3.040004572 -1.059422204 QMPSESLDPAFS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 QMPSESLDPAFSPR 14 0 Q15018 Q15018 FAM175B BRISC complex subunit Abro1 1 0 QMPSESLDPAFS(1)PR;QMPS(0.001)ES(0.442)LDPAFS(0.557)PR ; 172.42 0.00019715 27631700 3621.6 3048.6 2895.6 3076.9 3503.4 5180.2 4082.9 2278.64 3996.6 2767.2 TRUE FALSE FALSE 3334.946539 3312.1074 3002.913483 3064.168603 3461.624243 4105.768127 4197.455185 2973.386846 3558.182979 2863.359994 1.16469691 1.156720568 1.048737668 1.07013041 1.208937839 1.433898684 1.465919477 1.038425784 1.242660017 1 11.48349335 -5.803794531 0.154050582 0.93160567 1.49376492 0.04501429 0.149298764 10.40761448 0.549049181 0.542619497 1.466986596 1.57E-06 5.803794531 0.56215925 QMQVS(ph)LTS(ph)KK ddPTM_HeLa_Curcumin_4h_R1 1 QMQVSLTSKK 10 1 P55085 P55085 F2RL1 "Proteinase-activated receptor 2;Proteinase-activated receptor 2, alternate cleaved 1;Proteinase-activated receptor 2, alternate cleaved 2" 2 0 QMQVS(0.988)LT(0.267)S(0.745)KK 87.667 0.011637 9770200 1805.2 2069.4 1835.7 2095.7 1849.8 1963 1722.2 1586 2090.8 1725.7 TRUE FALSE FALSE 1662.316515 2248.269715 1903.732657 2087.028549 1827.742343 1555.851672 1770.520297 2069.564099 1861.444471 1785.667947 0.930921406 1.259063713 1.066117954 1.168766317 1.023562274 0.871299547 0.991517096 1.158985971 1.042435955 1 10.80224811 QMREEAERTRDELER ddPTM_HeLa_Curcumin_4h_R1 2 QMREEAERTRDELER 15 3 A0A5K1VW66;P35240-4;P35240-6;P35240-5;P35240-3;P35240;P35240-2 A0A5K1VW66 NF2 Merlin 0 0 ; ; 91.093 0.0017142 168169000 15647.1 12285.8 14599.4 14364.9 14115.5 15384.9 11546.3 8635.9 14081.3 12741.7 FALSE FALSE TRUE 14408.61552 13347.72981 15140.46661 14305.46185 13947.18188 12193.89832 11870.2581 11268.94616 12536.61662 13184.47313 1.092847275 1.012382496 1.148355832 1.085023399 1.057849013 0.924868078 0.900321006 0.854713423 0.950862162 1 13.6865523 -5.13882566 2.867816714 1.054697058 0.880361256 0.651873814 0.052901075 0.116292994 1.827368897 0.007209939 0.021558757 7.26E-06 5.13882566 -0.174335802 QMVIDVLHPGK ddPTM_HeLa_Curcumin_4h_R1 1 QMVIDVLHPGK 11 0 E7ETK0;A0A2R8Y849;A0A2R8YD14;P62847-2;P62847-3;P62847;P62847-4 E7ETK0 RPS24 40S ribosomal protein S24 0 0 78.653 0.017989 0 1645.8 1322.7 1667.9 1753.4 1140.4 2083.5 1596 1262.8 1812.6 1645.2 FALSE FALSE TRUE 1515.533193 1437.028294 1729.713841 1746.144895 1126.801475 1651.358614 1640.779465 1647.821907 1613.762315 1702.370578 0.8902487 0.844133653 1.016061875 1.025713742 0.661901404 0.970034748 0.963820384 0.967957229 0.947950074 1 10.73332941 QNAPPKGTDTQTPAVLS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 QNAPPKGTDTQTPAVLSPSK 20 1 P46087;P46087-4;P46087-2 P46087;P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 0 QNAPPKGTDTQT(0.003)PAVLS(0.903)PS(0.094)K;QNAPPKGTDTQTPAVLS(0.956)PS(0.044)K ; 101.2 0.00021378 72690000 7089.6 5049.6 5712.2 6349.3 4753.7 8690.2 6148.2 3816.6 8371.1 6247.8 TRUE FALSE FALSE 6528.450679 5486.064923 5923.899157 6323.028279 4697.015232 6887.754561 6320.701945 4980.263771 7452.811273 6464.910585 1.009828457 0.848590998 0.916315714 0.978053477 0.72653986 1.065406005 0.977693637 0.770353078 1.152809645 1 12.6584147 -7.281942909 23.5015517 1.004641226 0.90434104 0.282070926 0.105629483 424.8431711 486962.3044 0.015162494 0.017352375 5.22E-08 7.281942909 -0.100300187 QNAPPKGTDTQTPAVLSPSKTQAT(ph)LKPK ddPTM_HeLa_Curcumin_4h_R1 1 QNAPPKGTDTQTPAVLSPSKTQATLKPK 28 3 P46087;P46087-4;P46087-2 P46087;P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 0 QNAPPKGT(0.001)DT(0.002)QT(0.01)PAVLS(0.258)PS(0.055)KT(0.307)QAT(0.367)LKPK 49.638 0.0053181 28683000 1904.8 1165.8 1371.6 1563.9 1190.4 1787.2 1220.7 883.82 1516.6 1742.6 TRUE FALSE FALSE 1754.03307 1266.566557 1422.432703 1557.428996 1176.205257 1416.514574 1254.949557 1153.292649 1350.232774 1803.15522 0.97275767 0.702416821 0.788857602 0.863724309 0.652303942 0.785575506 0.695974225 0.639596989 0.748816718 1 10.81630788 -7.269725501 20.9822409 0.987135648 0.737376288 0.313384182 0.098914022 22.57031631 57152.74907 0.010760495 0.012446302 5.37E-08 7.269725501 -0.24975936 QNDTPKGPQPPT(ph)VSPIR ddPTM_HeLa_Curcumin_4h_R1 1 QNDTPKGPQPPTVSPIR 17 1 P46087;P46087-4;P46087-2 P46087;P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 0 QNDTPKGPQPPT(0.656)VS(0.344)PIR 71.202 0.014937 30345000 2841.3 2395.4 2478.9 2656.2 1865.6 3363.2 1867.7 1576.2 3491.7 2670.3 TRUE FALSE FALSE 2616.408107 2602.447702 2570.770215 2645.209348 1843.353938 2665.634409 1920.102635 2056.776124 3108.669246 2763.092726 0.946912886 0.94186043 0.930395926 0.957336438 0.667134302 0.964728539 0.694910676 0.744374629 1.125068738 1 11.43206826 -4.384265139 0.312921285 0.99609094 0.515240827 0.546029588 0.093710969 3.594870814 0.269839576 0.032559699 0.651423429 4.13E-05 4.384265139 -0.480850113 QNDTPKGPQPPTVS(ph)PIR ddPTM_HeLa_Curcumin_4h_R1 1 QNDTPKGPQPPTVSPIR 17 1 P46087;P46087-4;P46087-2 P46087;P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 0 QNDTPKGPQPPT(0.418)VS(0.582)PIR 53.718 0.020264 65563000 1818.4 1668.1 1656.3 1618.3 1376.5 2393.9 1314.1 1043.5 2799.7 1797.4 TRUE FALSE FALSE 1674.471721 1812.283131 1717.683935 1611.603903 1360.086137 1897.378155 1350.970109 1361.658346 2492.579915 1859.859516 0.900321614 0.974419366 0.923555742 0.866519159 0.731284339 1.020172835 0.726382879 0.732129677 1.340197952 1 10.86097794 -1.306381635 0.182815234 0.99797177 2.87E-12 0.364646452 0.139797176 32.90140106 0.397943822 0.096443186 9.00805222 0.04938765 1.306381635 -0.99797177 QNESTNGNS(ph)EVTPNVNQGK ddPTM_HeLa_Curcumin_4h_R1 1 QNESTNGNSEVTPNVNQGK 19 0 Q9HCM1 Q9HCM1 KIAA1551 Uncharacterized protein KIAA1551 1 0 QNES(0.001)T(0.011)NGNS(0.494)EVT(0.494)PNVNQGK 65.295 0.014161 7406700 3526.5 2638.6 2931.9 3444.8 3166.9 4385.6 3178.2 3122.5 3579.5 3167.3 TRUE FALSE FALSE 3247.373804 2866.668827 3040.558793 3430.54633 3129.136786 3475.977124 3267.371738 4074.535876 3186.837805 3277.363439 0.990849463 0.874687498 0.927745381 1.046739672 0.954772592 1.060601666 0.996951299 1.243235897 0.972378518 1 11.67831995 QNEVANVQPSSK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 QNEVANVQPSSKR 13 1 Q6ZW49-2;Q6ZW49-1;Q6ZW49 Q6ZW49-2 PAXIP1 PAX-interacting protein 1 0 1 ; QNEVANVQPSSK(1)R;QNEVANVQPSSK(1)R 201.09 5.67E-15 4375200 2128.15 1918.07 1880.04 1616.51 1585.9 2003.38 1421.87 1039.97 1882.74 1518.79 FALSE TRUE FALSE 1959.704682 2083.859424 1949.715936 1609.82131 1566.989178 1587.856405 1461.763845 1357.052066 1676.208132 1571.567839 1.246974284 1.325974846 1.240618373 1.02434096 0.997086565 1.010364532 0.930130923 0.863502059 1.066583376 1 10.61798883 -5.969178619 3.019596921 1.146888499 0.952133581 0.539081571 0.096973523 0.231428142 4.330130586 0.019468395 0.036371074 1.07E-06 5.969178619 -0.194754918 QNGDDPLLTYR ddPTM_HeLa_Curcumin_4h_R1 1 QNGDDPLLTYR 11 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 152.04 1.84E-06 4300900 2082.7 1417.4 1647.2 1851.1 1961.2 2131.3 1913.9 1696.2 1659.9 1765 FALSE FALSE TRUE 1917.852097 1539.91374 1708.246681 1843.440639 1937.813971 1689.244355 1967.598883 2213.363572 1477.813123 1826.333619 1.050110493 0.843172203 0.935342077 1.009366865 1.061040519 0.924937447 1.077349101 1.211916349 0.809169315 1 10.83473461 -4.388929511 3.282345522 1.001197283 1.216823467 0.382094391 0.088739021 0.182550557 3.161196104 0.009537404 0.080886442 4.08E-05 4.388929511 0.215626184 QNGSNDSDRYS(ph)DNEEDSKIELK ddPTM_HeLa_Curcumin_4h_R1 1 QNGSNDSDRYSDNEEDSKIELK 22 2 G5E972;P42167;H0YJH7;P42167-3;P42167-2 G5E972 TMPO "Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin" 1 0 QNGS(0.003)NDS(0.009)DRY(0.455)S(0.531)DNEEDS(0.001)KIELK 65.855 0.0025033 26139000 2465.8 1806.8 2471.8 3333.7 2641.9 3351.4 1753.8 1454.8 3381.8 2457.2 TRUE FALSE FALSE 2270.629328 1962.971741 2563.407082 3319.906033 2610.397068 2656.281862 1803.006908 1898.361823 3010.825001 2542.587517 0.893038809 0.77203704 1.008188338 1.305719473 1.026669505 1.044716001 0.709122851 0.746625951 1.184157863 1 11.31208172 -4.754353238 24.98836476 0.976059002 0.727874282 0.368703193 0.144942205 140.1276871 494128.7484 0.01942288 0.069670084 1.76E-05 4.754353238 -0.24818472 QNGSNDSDRYS(ph)DNEEGK ddPTM_HeLa_Curcumin_4h_R1 2 QNGSNDSDRYSDNEEGK 17 1 P42166 P42166 TMPO "Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin" 1 0 QNGS(0.001)NDS(0.008)DRY(0.072)S(0.919)DNEEGK;QNGS(0.008)NDS(0.091)DRY(0.171)S(0.729)DNEEGK ; 81.017 0.0038909 49466000 4854.3 4394.8 5044.9 4903.5 5729.7 4731.8 3897.3 2642.7 4348.2 3829.3 TRUE FALSE FALSE 4470.077033 4774.666929 5231.868432 4883.210616 5661.37707 3750.371342 4006.647749 3448.447065 3871.213339 3962.36789 1.128132762 1.205003438 1.320389367 1.23239708 1.428786329 0.94649751 1.0111751 0.870299568 0.97699493 1 11.95214712 QNPEQS(ph)ADEDAEK ddPTM_HeLa_Curcumin_4h_R1 2 QNPEQSADEDAEK 13 0 Q99613-2;Q99613;B5ME19;H3BPE3 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 0 QNPEQS(1)ADEDAEK;QNPEQS(1)ADEDAEK ; 126.07 0.0019472 13713200 1865.92 2075.5 2116.4 1985.68 2564.7 1953.12 2070.7 2027 1555.33 2277.5 TRUE FALSE FALSE 1718.230463 2254.896972 2194.835646 1977.463782 2534.117628 1548.020896 2128.798269 2645.022969 1384.71419 2356.642955 0.729100884 0.956825881 0.931339913 0.839101985 1.075308256 0.656875447 0.903318114 1.122368988 0.587579118 1 11.20251748 QNPQS(ph)PPQDSSVTSK ddPTM_HeLa_Curcumin_4h_R1 1 QNPQSPPQDSSVTSK 15 0 C9JEF4;C9J172;Q9BRX7;A0A2R8YCS4;E7EP63;E7ER52;A6NDI8;Q9UBN7 C9JEF4 HDAC6 Histone deacetylase 6 1 0 QNPQS(0.725)PPQDS(0.124)S(0.124)VT(0.023)S(0.004)K 86.014 0.010928 2893100 1246.2 788.74 843.95 1188.7 1201.5 1173 925.48 798.33 1228.9 998.68 TRUE FALSE FALSE 1147.561955 856.915171 875.2275294 1183.781474 1187.172897 929.7065776 951.446478 1041.737142 1094.092745 1033.384056 1.110489318 0.829232042 0.84695281 1.145538745 1.148820606 0.899671881 0.920709462 1.008083235 1.05874746 1 10.01316081 NIIGSS(ph)PVADFSAIK ddPTM_HeLa_Curcumin_4h_R1 1 NIIGSSPVADFSAIK 15 0 P42566;B1AUU8 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 0 NIIGS(0.097)S(0.903)PVADFSAIK 201.04 2.59E-09 44858000 2439.8 2072.7 2091 2031.9 2594.4 2719.5 2396.3 4431.8 2118.8 1557.8 TRUE FALSE FALSE 2246.687256 2251.854952 2168.494299 2023.492536 2563.463474 2155.445045 2463.533729 5783.035419 1886.372941 1611.933434 1.39378414 1.39699004 1.345275341 1.25532016 1.590303557 1.337179935 1.52830984 3.587639102 1.170254864 1 10.65457645 -4.239602976 3.033319029 1.259263175 4.029636778 0.950704404 0.154168751 0.080056457 1.034216231 0.028521165 0.545534431 5.76E-05 4.239602976 2.770373604 up QNS(ph)PVTQDGIQESPWQDR ddPTM_HeLa_Curcumin_4h_R1 4 QNSPVTQDGIQESPWQDR 18 0 O75815 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 0 QNS(0.841)PVT(0.159)QDGIQESPWQDR;QNS(0.982)PVT(0.018)QDGIQESPWQDR;QNS(0.97)PVT(0.029)QDGIQES(0.001)PWQDR;QNS(0.994)PVT(0.004)QDGIQES(0.002)PWQDR ;;; 259.55 1.82E-42 51051400 5646.43 4943.95 5006.78 5219.3 4828.87 5610.42 4155.13 3826.47 6191.11 4711.14 TRUE FALSE FALSE 5199.509107 5371.283008 5192.335671 5197.70392 4771.288879 4446.75565 4271.711765 4993.143088 5511.960722 4874.851764 1.066598403 1.101835147 1.065126884 1.066228097 0.978755685 0.912182742 0.876275212 1.024265625 1.130692991 1 12.25114263 -5.558739523 4.150945592 1.042864525 0.932595848 0.551932921 0.051697166 0.127181935 4.844131233 0.007045019 0.014981445 2.76E-06 5.558739523 -0.110268677 QNS(ph)SSSDSGGSIVR ddPTM_HeLa_Curcumin_4h_R1 2 QNSSSSDSGGSIVR 14 0 A0A2R8Y4W2;A0A2R8YE63;Q12929-2;Q12929 A0A2R8Y4W2 EPS8 Epidermal growth factor receptor kinase substrate 8 1 0 QNS(0.485)S(0.485)S(0.023)S(0.001)DS(0.005)GGSIVR;QNS(0.493)S(0.079)S(0.079)S(0.341)DS(0.008)GGSIVR ; 211.49 8.09E-10 55660000 4331.2 3802.2 3702.1 3533.1 3938.5 4579.4 3404.3 2247.5 3958.2 3689.8 TRUE FALSE FALSE 3988.38095 4130.845226 3839.303083 3518.480968 3891.53596 3629.58082 3499.815496 2932.752404 3523.995363 3818.020275 1.04462016 1.081933811 1.005574304 0.92154591 1.019254922 0.950644721 0.916657127 0.768134319 0.922990217 1 11.89860905 -3.215233366 0.643667273 1.02230168 7.61E-12 0.665005861 0.048681879 3.354149941 0.355541346 0.006796622 3.457582303 0.000609209 3.215233366 -1.02230168 QNSPAGNKENIKPNET(ph)SPSFSK ddPTM_HeLa_Curcumin_4h_R1 2 QNSPAGNKENIKPNETSPSFSK 22 2 H0YH87;A0A2R8Y7P6;A0A2R8YDM9;A0A5F9ZHH4;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A2R8Y5A6;A0A5F9ZHX3;A0A5F9ZHW5;Q99700-2;Q99700-5;Q99700-4;Q99700;F8W0B5;F8WB06 H0YH87;F8WB06 ATXN2 Ataxin-2 1 0 QNSPAGNKENIKPNET(0.496)S(0.496)PS(0.007)FS(0.001)K;QNSPAGNKENIKPNET(0.434)S(0.434)PS(0.125)FS(0.007)K ; 87.654 0.00020315 167605000 4000.6 3108.42 3074.14 3833.1 3875.6 3834.1 2671.99 4499.9 3924.4 3167.14 TRUE FALSE FALSE 3683.948289 3377.097974 3188.070333 3817.239648 3829.386001 3038.864441 2746.958848 5871.898795 3493.903138 3277.197879 1.124115303 1.030483388 0.972803734 1.16478766 1.168493982 0.927275237 0.838203535 1.791743743 1.066125168 1 11.67824707 -4.251396408 24.87186106 1.046734368 1.791744182 0.836848907 0.100396901 405.2512039 1003601.316 0.014371121 0.263019185 5.61E-05 4.251396408 0.745009813 ENQEPLRS(ph)PEVGDEEALRPLTK ddPTM_HeLa_Curcumin_4h_R1 1 ENQEPLRSPEVGDEEALRPLTK 22 2 P48681 P48681 NES Nestin 1 0 ENQEPLRS(1)PEVGDEEALRPLTK 69.081 0.0007608 77693000 2483.2 1653 1979.4 1794.3 2341.6 2599.2 2852.2 5343.5 2145.2 1879.9 TRUE FALSE FALSE 2286.6521 1795.877954 2052.758305 1786.875662 2313.677949 2060.096621 2932.225056 6972.708552 1909.876927 1945.226385 1.175519784 0.923223111 1.0552799 0.918595221 1.189413205 1.059052374 1.507395272 3.584522915 0.981827587 1 10.92572235 -4.239576682 2.578035652 1.065822276 4.19671032 0.985590855 0.091974578 0.045423913 0.365044625 0.013723145 0.314557748 5.76E-05 4.239576682 3.130888044 up QNTAWDTETS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 QNTAWDTETSPR 12 0 Q8NDV7-2;Q8NDV7-6;Q8NDV7-5;Q8NDV7 Q8NDV7-2 TNRC6A Trinucleotide repeat-containing gene 6A protein 1 0 QNTAWDTET(0.082)S(0.918)PR;QNTAWDTET(0.086)S(0.914)PR ; 190.34 5.70E-06 66010000 7716.7 7744.5 8978.5 7821.2 9949.6 9717.2 8052.2 4779.8 7177.6 7168.5 TRUE FALSE FALSE 7105.915052 8413.900071 9311.251108 7788.837947 9830.957518 7701.743185 8278.123061 6237.139017 6390.235237 7417.604841 0.957979726 1.134314951 1.255290799 1.050047571 1.325354711 1.038305942 1.116010254 0.8408562 0.861495776 1 12.8567377 -7.259978669 24.90106155 0.980157092 1.117905793 0.247882502 0.128392362 136.2329946 2322403.098 0.019666813 0.023416601 5.50E-08 7.259978669 0.137748701 QNTQSDIGGS(ph)GK ddPTM_HeLa_Curcumin_4h_R1 2 QNTQSDIGGSGK 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 QNT(0.008)QS(0.038)DIGGS(0.954)GK;QNTQS(0.001)DIGGS(0.999)GK ; 105.58 0.0068931 11443400 3687.3 3705.6 3597.8 3024.3 3254.7 3644.6 1812.98 1700.3 4109 4162 TRUE FALSE FALSE 3395.446314 4025.895552 3731.137633 3011.786248 3215.889828 2888.668877 1863.847339 2218.713643 3658.25298 4306.62919 0.788423188 0.934813603 0.866370767 0.699337258 0.746730142 0.670749384 0.432785656 0.51518567 0.849446938 1 12.07234339 -4.05073197 0.282009405 0.955366806 2.03E-14 0.801323977 0.075404119 3.093320975 0.16852082 0.042412131 1.043090524 8.90E-05 4.05073197 -0.955366806 QNVAVNELCGR ddPTM_HeLa_Curcumin_4h_R1 1 QNVAVNELCGR 11 0 Q15942;Q15942-2;H0Y2Y8;C9JJK5 Q15942 ZYX Zyxin 0 0 94.363 0.0043 0 700.12 538.52 726.38 806.97 746.91 924.39 509.62 657.7 1034.6 698.07 FALSE FALSE TRUE 644.7047632 585.0672692 753.3002818 803.630972 738.0035861 732.661094 523.9185656 858.2297023 921.1069684 722.3278805 0.892537559 0.809974646 1.04287859 1.112557045 1.021701648 1.014305433 0.725319595 1.188144228 1.275192324 1 9.496510047 QNVAYEYLCHLEEAKR ddPTM_HeLa_Curcumin_4h_R1 1 QNVAYEYLCHLEEAKR 16 1 P46940;A0A0J9YXZ5;A0A087X225 P46940 IQGAP1 Ras GTPase-activating-like protein IQGAP1 0 0 62.077 0.010943 13976000 2241.5 1703 1638.1 1584 1717.6 2172.2 1854.1 1534.5 2192.2 1762.8 FALSE FALSE TRUE 2064.08291 1850.199732 1698.809427 1577.445828 1697.118742 1721.661234 1906.121056 2002.361986 1951.721145 1824.057169 1.131588935 1.014332096 0.931335627 0.864800651 0.930408745 0.943863637 1.044989756 1.09775177 1.069989021 1 10.83293523 -6.999051264 9.922649437 1.062715814 0.965337474 0.298132963 0.067492882 0.106401263 215.6523065 0.013165016 0.016967451 1.00E-07 6.999051264 -0.09737834 QNVGTLESFS(ph)PGDFR ddPTM_HeLa_Curcumin_4h_R1 2 QNVGTLESFSPGDFR 15 0 Q6ULP2-7;Q6ULP2-8;Q6ULP2-6;Q6ULP2;Q6ULP2-9 Q6ULP2-7 AFTPH Aftiphilin 1 0 QNVGTLESFS(1)PGDFR;QNVGT(0.008)LES(0.027)FS(0.966)PGDFR ; 200 1.88E-07 6747200 3381.1 3212.49 3639.5 4271.6 4318.2 3258.3 3378.8 2211.4 3813.7 3793.96 TRUE FALSE FALSE 3113.482367 3490.163321 3774.383072 4253.925251 4266.708285 2582.491851 3473.600034 2885.64568 3395.346651 3925.799828 0.793082303 0.88903242 0.961430342 1.083581802 1.086837962 0.657825657 0.884813334 0.735046565 0.864880228 1 11.9387709 -5.251265395 24.99815086 0.928311032 0.771787012 0.412152299 0.1031703 760.8806136 1869528.922 0.017103565 0.043068085 5.61E-06 5.251265395 -0.15652402 QPAPGGGGGGGPS(ph)PCGPGGGGR ddPTM_HeLa_Curcumin_4h_R1 2 QPAPGGGGGGGPSPCGPGGGGR 22 0 Q9H6S0;D6RF50;D6RA70 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 1 0 QPAPGGGGGGGPS(1)PCGPGGGGR;QPAPGGGGGGGPS(1)PCGPGGGGR ; 112.36 1.84E-05 8555300 1996.41 1694.73 1935.4 1766.49 1897.07 2287.8 1973.93 1062.99 2110.2 1804.07 TRUE FALSE FALSE 1838.392042 1841.21491 2007.127627 1759.180732 1874.448679 1813.284491 2029.313163 1387.090758 1878.716339 1866.761298 0.984802955 0.986315128 1.075192435 0.942370476 1.004118031 0.971353163 1.087076942 0.743046665 1.006404162 1 10.86632175 -4.248854191 25 0.998418015 0.743046506 0.773996042 0.042496091 661.3594134 1313743.091 0.005182403 0.124508673 5.64E-05 4.248854191 -0.255371509 SES(ph)PFRETEPLVSPHQDK ddPTM_HeLa_Curcumin_4h_R1 2 SESPFRETEPLVSPHQDK 18 1 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 0 S(0.175)ES(0.794)PFRET(0.031)EPLVSPHQDK;S(0.147)ES(0.651)PFRET(0.199)EPLVS(0.003)PHQDK ; 113.63 0.00024407 21990700 3834.7 3442.5 3517.2 3088.7 3778.4 4782 2970.3 846.74 4186.1 3267.7 TRUE FALSE FALSE 3531.179449 3740.054361 3647.550526 3075.919778 3733.345048 3790.159296 3053.638624 1104.907128 3726.895303 3381.252332 1.044340706 1.106115129 1.078757267 0.909698383 1.104130861 1.120933584 0.903108767 0.326774526 1.102223359 1 11.72334197 -4.279395279 3.149466533 1.034748822 0.235387615 0.919221032 0.064616916 0.060689458 0.939175279 0.008491234 0.116534435 5.26E-05 4.279395279 -0.799361206 down MKETIQGTGSWGPEPPGPGIPPAYS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 MKETIQGTGSWGPEPPGPGIPPAYSSPR 28 1 Q9H4L4 Q9H4L4 SENP3 Sentrin-specific protease 3 1 0 MKETIQGTGSWGPEPPGPGIPPAY(0.032)S(0.484)S(0.484)PR 100.88 2.42E-08 24714000 829.35 457.51 669.56 541.69 760.06 1006.5 586.52 123.12 736.54 624.98 TRUE FALSE FALSE 763.7060724 497.0551258 694.3744826 539.4486303 750.9967809 797.7405544 602.9761727 160.6587212 655.7434047 646.6980085 1.180931536 0.768604695 1.073722933 0.834158484 1.161278945 1.233559627 0.93239219 0.248429281 1.013987048 1 9.336948357 -4.279282097 3.65751438 1.059762946 0.173448118 0.731810228 0.140764644 0.095370792 2.343312115 0.019829295 0.223068435 5.26E-05 4.279282097 -0.886314828 down QPCPS(ph)ESDIITEEDKSK ddPTM_HeLa_Curcumin_4h_R1 1 QPCPSESDIITEEDKSK 17 1 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 1 0 QPCPS(0.969)ES(0.031)DIITEEDKSK 118.16 0.00031538 39802000 1723.9 1382.5 1411.2 1853.2 1741.4 2193.5 1618.6 1712.8 2214.9 1874.5 TRUE FALSE FALSE 1587.451496 1501.99714 1463.500313 1845.531949 1720.634942 1738.543374 1664.01356 2235.024835 1971.931011 1939.638735 0.818426373 0.774369532 0.754522111 0.951482312 0.887090421 0.896323291 0.857898705 1.152289235 1.016648603 1 10.92157226 -4.257192849 24.57404615 0.889342024 1.152289368 0.480306399 0.083534529 259.9933627 1504468.566 0.01286589 0.133454658 5.53E-05 4.257192849 0.262947344 QPDAKDGDSYDPYDFSDT(ph)EEEMPQVHTPK ddPTM_HeLa_Curcumin_4h_R1 1 QPDAKDGDSYDPYDFSDTEEEMPQVHTPK 29 1 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 0 QPDAKDGDS(0.002)Y(0.002)DPY(0.068)DFS(0.225)DT(0.69)EEEMPQVHT(0.012)PK 50.803 0.0068213 6377300 2528.5 2052.3 1533.9 2243.9 1480.4 2603.7 1594.5 1537.5 3358.7 3028.3 TRUE FALSE FALSE 2328.366557 2229.691667 1590.747683 2234.615336 1462.747197 2063.66327 1639.237379 2006.276672 2990.259013 3133.5332 0.743048313 0.711558335 0.507653049 0.713129619 0.466804436 0.658573929 0.523127497 0.640260225 0.954277112 1 11.61357456 -8.18699086 0.446040001 1.020600694 0.564484426 0.788969381 0.077429433 0.292487246 0.135194624 0.05629199 0.027598145 6.50E-09 8.18699086 -0.456116268 TT(ph)SGDDACNLTSFR ddPTM_HeLa_Curcumin_4h_R1 1 TTSGDDACNLTSFR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0U1RQT6 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 T(0.062)T(0.464)S(0.464)GDDACNLT(0.008)S(0.001)FR 122.1 0.0046815 11251000 1185.3 1329.8 1366.2 1304.6 1518.9 1730.5 1880.3 5080.5 1119.3 1155.9 TRUE FALSE FALSE 1091.482254 1444.741987 1416.832574 1299.201911 1500.78811 1371.574793 1933.056157 6629.521062 996.5155904 1196.067439 0.912559124 1.207910139 1.184575825 1.086227974 1.254768804 1.146737005 1.616176559 5.542765271 0.833160036 1 10.22408302 -4.239517429 2.919062054 1.03417265 6.453761814 0.989871192 0.134561585 0.03300299 0.379983678 0.021491193 0.429181337 5.76E-05 4.239517429 5.419589164 up QPEYS(ph)PESPR ddPTM_HeLa_Curcumin_4h_R1 1 QPEYSPESPR 10 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 0 QPEYS(0.96)PES(0.04)PR 136.27 0.0020321 988490000 1014.5 958.61 819.59 1208.2 1018.4 1188.8 969.88 1154.8 798.35 1112.2 TRUE FALSE FALSE 934.2012545 1041.467977 849.9647264 1203.200789 1006.256245 942.2294795 997.0922225 1506.893204 710.7730024 1150.848867 0.811749728 0.904956338 0.738554601 1.045489832 0.874360026 0.818725644 0.866397188 1.309375407 0.617607596 1 10.16848267 -4.258961021 24.82234573 0.895650537 1.309375569 0.533349349 0.122343806 102.7075758 1028611.054 0.013121989 0.119203149 5.51E-05 4.258961021 0.413725031 QPEYSPES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 QPEYSPESPR 10 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 0 QPEYS(0.003)PES(0.997)PR 153.49 0.00065205 78625000 1118.5 1246 998.98 1388.4 1131.1 1170.8 867.81 983.98 1226.4 1142.8 TRUE FALSE FALSE 1029.969545 1353.698688 1036.003078 1382.655169 1117.612371 927.9628824 892.158413 1283.990972 1091.866988 1182.512215 0.871001189 1.144765078 0.876103489 1.169252335 0.945116978 0.784738517 0.754460209 1.085816245 0.923345209 1 10.20763937 -5.499792993 24.23789983 0.96767243 0.86328002 0.131971223 0.126597523 850.6163164 893066.5218 0.017735841 0.039377859 3.16E-06 5.499792993 -0.10439241 QPGQGS(ph)PTPDNDPGRETDDK ddPTM_HeLa_Curcumin_4h_R1 1 QPGQGSPTPDNDPGRETDDK 20 1 P61129 P61129 ZC3H6 Zinc finger CCCH domain-containing protein 6 1 0 QPGQGS(0.961)PT(0.036)PDNDPGRET(0.003)DDK 52.654 0.013028 4463300 1073.3 1481.7 1060.8 1606.9 915.12 1461.4 892.75 755.76 1536.2 1392.8 TRUE FALSE FALSE 988.3471725 1609.771546 1100.114181 1600.251074 904.2077917 1158.289167 917.7981623 986.1877449 1367.682703 1441.199696 0.685780864 1.116966337 0.763332232 1.110360402 0.627399377 0.803697898 0.636829278 0.68428251 0.948989031 1 10.49305454 -5.712001426 24.99988695 0.879091098 0.692653746 0.391619678 0.141463639 124.2108428 62810.45379 0.022736109 0.045472161 1.94E-06 5.712001426 -0.186437353 NLATSADT(ph)PPSTVPGTGK ddPTM_HeLa_Curcumin_4h_R1 2 NLATSADTPPSTVPGTGK 18 0 Q96Q15;J3KRA9;Q96Q15-4;Q96Q15-3;Q96Q15-2 Q96Q15 SMG1 Serine/threonine-protein kinase SMG1 1 0 NLAT(0.022)S(0.003)ADT(0.975)PPS(0.001)TVPGTGK;NLAT(0.084)S(0.152)ADT(0.609)PPS(0.077)T(0.077)VPGTGK ; 224.99 3.48E-18 24768000 9178 8131.8 9018.4 8326.4 8180.1 10365 6225.5 2285.8 9400 7662.9 TRUE FALSE FALSE 8451.551615 8834.676557 9352.629837 8291.947563 8082.55765 8215.182162 6400.170775 2982.729897 8368.843518 7929.185205 1.065878952 1.114197276 1.17951966 1.045750269 1.019342775 1.036068896 0.807166261 0.376171047 1.055448107 1 12.95295691 -4.278239215 1.742835563 1.05082951 0.156718746 0.946954026 0.050131473 0.163547337 0.496633863 0.008515748 0.239054865 5.27E-05 4.278239215 -0.894110764 down ES(ph)SPIPSPTSDRK ddPTM_HeLa_Curcumin_4h_R1 1 ESSPIPSPTSDRK 13 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 ES(0.5)S(0.5)PIPSPTSDRK 83.633 0.0087154 46422000 1043.2 926.43 850.46 912.79 1131.5 1278 1166.7 2220.2 1189.1 897.31 TRUE FALSE FALSE 960.6296192 1006.506481 881.9787957 909.0131168 1118.007602 1012.928394 1199.434462 2897.128759 1058.658705 928.4914557 1.034613311 1.084023418 0.949905129 0.979021521 1.20411189 1.09093992 1.291809908 3.120253549 1.140192189 1 9.858744824 -4.239312377 2.955821674 1.032477257 3.534422005 0.98439972 0.07723083 0.033781873 0.403516761 0.010367101 0.204504572 5.76E-05 4.239312377 2.501944748 up QPGYQPPNPHPGPS(ph)SPPAAPASK ddPTM_HeLa_Curcumin_4h_R1 1 QPGYQPPNPHPGPSSPPAAPASK 23 0 Q9BUL9 Q9BUL9 RPP25 Ribonuclease P protein subunit p25 1 0 QPGY(0.001)QPPNPHPGPS(0.934)S(0.065)PPAAPASK 75.868 0.00044626 29939000 3237.4 2863.8 2522.3 2839.7 3840.9 3730 2990.6 3022.5 3017.9 2673.1 TRUE FALSE FALSE 2981.156374 3111.334111 2615.778657 2827.950074 3795.099776 2956.355954 3074.508187 3944.046336 2686.84392 2765.990026 1.077789994 1.124853699 0.945693452 1.022400677 1.372058373 1.068823794 1.111539868 1.425907649 0.971385976 1 11.43358024 -1 0.380110081 1.032063237 5.548769649 0.468619831 0.112309383 41.15931675 0.499630663 0.028124823 138.5968705 0.1 1 4.516706412 QPLLLS(ph)EDEEDTK ddPTM_HeLa_Curcumin_4h_R1 4 QPLLLSEDEEDTK 13 0 Q99613-2;Q99613;B5ME19;H3BPE4 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 0 QPLLLS(0.993)EDEEDT(0.007)K;QPLLLS(1)EDEEDTK;QPLLLS(1)EDEEDTK;QPLLLS(1)EDEEDTK ;;; 193.77 5.44E-06 189766000 11639.8 13551.1 12659.2 12563.5 10593.4 12263.7 11705 8988.9 11748.6 15146.1 TRUE FALSE FALSE 10718.49755 14722.3967 13128.36109 12511.51557 10467.08062 9720.07038 12033.4108 11729.57423 10459.80797 15672.42585 0.683908008 0.939382125 0.83767256 0.798313911 0.667866017 0.620202033 0.767807799 0.748421102 0.667401976 1 13.93594088 -13.52287874 0.293681547 3.117508161 0.731237924 0 0.136813107 29.12442591 0.394107056 36.3754359 0.040678056 3.00E-14 13.52287874 -2.386270238 QPLLLS(ph)EDEEDTKR ddPTM_HeLa_Curcumin_4h_R1 9 QPLLLSEDEEDTKR 14 1 Q99613-2;Q99613;B5ME19;H3BPE4 Q99613-2 EIF3C;EIF3CL Eukaryotic translation initiation factor 3 subunit C;Eukaryotic translation initiation factor 3 subunit C-like protein 1 0 QPLLLS(0.99)EDEEDT(0.01)KR;QPLLLS(1)EDEEDTKR;QPLLLS(0.958)EDEEDT(0.042)KR;QPLLLS(1)EDEEDTKR;QPLLLS(1)EDEEDTKR;QPLLLS(0.997)EDEEDT(0.003)KR;QPLLLS(1)EDEEDTKR;QPLLLS(1)EDEEDTKR;QPLLLS(1)EDEEDTKR ;;;;;;;; 171.81 0.00020093 12174311000 20605.7 22131.3 18453 21621.7 21112.9 23092.8 18203.7 16833.5 23153.3 22756.4 TRUE FALSE FALSE 18974.7371 24044.23096 19136.88441 21532.23513 20861.14246 18303.09297 18714.44683 21965.95666 20613.44092 23547.18321 0.805817704 1.021108586 0.812703764 0.914429337 0.885929424 0.777294371 0.794763716 0.93284859 0.875410054 1 14.52326687 -9.492949221 1.118556778 1.003560313 0.861371641 0.014695994 0.080733079 0.479898439 1.029541793 0.055509742 0.012177689 3.21E-10 9.492949221 -0.142188672 AVSLDSPVSVGSS(ph)PPVK ddPTM_HeLa_Curcumin_4h_R1 1 AVSLDSPVSVGSSPPVK 17 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 0 AVSLDSPVSVGS(0.044)S(0.955)PPVK 162.7 8.08E-13 0 2248.2 1974.6 1519.1 2125.1 2119.8 2820 1676.5 280.85 2123.9 1881.5 TRUE FALSE FALSE 2070.252598 2145.275625 1575.399182 2116.306899 2094.522769 2235.100212 1723.538078 366.4798721 1890.913484 1946.881985 1.063368306 1.10190327 0.809190898 1.087023721 1.075834481 1.148040934 0.88528123 0.188239387 0.971252237 1 10.92694972 -4.278079308 3.268257175 1.033518999 0.086110479 0.888002526 0.089431221 0.065530067 1.132777076 0.011617519 0.15287427 5.27E-05 4.278079308 -0.94740852 down QPPGPVPT(ph)PPLPSER ddPTM_HeLa_Curcumin_4h_R1 1 QPPGPVPTPPLPSER 15 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QQI0 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 0 QPPGPVPT(0.902)PPLPS(0.098)ER 99.915 0.011569 11364000 405.76 344.28 452.71 445.31 279.99 361.5 472.86 398.83 592.3 502.72 TRUE FALSE FALSE 373.6436678 374.0380291 469.4878308 443.4674252 276.6513021 286.5208251 486.127179 520.431431 527.3261719 520.1894826 0.71828378 0.719041891 0.90253234 0.852511325 0.531827942 0.550800881 0.93451943 1.000465116 1.013719403 1 9.02289342 -9.331640445 0.952716399 1.00615679 0.767467524 0.278596567 0.146983033 0.706048752 1.100432378 0.11988785 0.028558932 4.66E-10 9.331640445 -0.238689265 QPPGTQQSHS(ph)SPGEITSSPQGLDNPALLR ddPTM_HeLa_Curcumin_4h_R1 2 QPPGTQQSHSSPGEITSSPQGLDNPALLR 29 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 0 QPPGTQQSHS(0.5)S(0.5)PGEITSSPQGLDNPALLR;QPPGTQQS(0.001)HS(0.499)S(0.499)PGEITSSPQGLDNPALLR ; 113.8 2.30E-11 46802000 704.38 858.61 651.6 708.07 660.39 866.02 649.48 710.41 965.26 612.5 TRUE FALSE FALSE 648.6275797 932.8244225 675.7488692 705.140194 652.5152806 686.3976899 667.7026608 927.0107387 859.373393 633.7843294 1.023420034 1.471832577 1.06621265 1.112586981 1.029554141 1.083014613 1.053517151 1.462659608 1.355939794 1 9.307848179 -1.00000002 0.076104087 0.826864755 1.856250297 0 0.196325308 269.842139 1.519164741 3.362812131 29.54451433 0.099999995 1.00000002 1.029385542 QPPGTQQSHSS(ph)PGEITSS(ph)PQGLDNPALLR ddPTM_HeLa_Curcumin_4h_R1 1 QPPGTQQSHSSPGEITSSPQGLDNPALLR 29 0 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 2 0 QPPGT(0.028)QQS(0.03)HS(0.246)S(0.695)PGEIT(0.032)S(0.308)S(0.66)PQGLDNPALLR 71.909 0.00036278 10629000 580.52 520.93 548.98 719.62 689.66 782.49 523.78 445.2 592.36 683.92 TRUE FALSE FALSE 534.5712294 565.956868 569.3256817 716.6424031 681.4362549 620.1927535 538.4758571 580.9394306 527.37959 707.6861691 0.755378942 0.799728598 0.80448892 1.012655658 0.962907408 0.876366927 0.760896398 0.820899794 0.745216754 1 9.466965914 -9.554937658 1.349827129 0.999308408 0.840802874 0 0.111238697 0.436065003 1.433461965 0.06207387 0.014938742 2.79E-10 9.554937658 -0.158505535 QPPPLAPQS(ph)PQGGVMGGSNSNQQQQMR ddPTM_HeLa_Curcumin_4h_R1 1 QPPPLAPQSPQGGVMGGSNSNQQQQMR 27 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 0 QPPPLAPQS(0.655)PQGGVMGGS(0.215)NS(0.13)NQQQQMR 43.884 0.016542 13668000 619.75 466.59 556.44 471.65 463.97 737.56 392.75 437.31 738.17 534.23 TRUE FALSE FALSE 570.6961335 506.9199605 577.0621559 469.6984373 458.4374608 584.581742 403.769508 570.6438059 657.1945978 552.7944527 1.032383973 0.917013472 1.043900048 0.849680084 0.829309083 1.057502909 0.730415267 1.032289313 1.188858887 1 9.110599328 -6.264630619 24.98728054 1.008696945 0.895267623 0.260111184 0.11020002 268.2442189 2100341.942 0.012861527 0.020153978 5.44E-07 6.264630619 -0.113429322 QPPYQLRPS(ph)LFVLSPIKEPAK ddPTM_HeLa_Curcumin_4h_R1 1 QPPYQLRPSLFVLSPIKEPAK 21 2 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 0 QPPY(0.049)QLRPS(0.798)LFVLS(0.153)PIKEPAK 40.432 0.018804 63083000 3052.1 2764.4 3399.8 2717.2 2882.8 7223.8 5470.4 4482.8 3458.1 3315.7 TRUE FALSE FALSE 2810.523064 3003.342418 3525.799579 2705.956946 2848.424493 5725.502451 5623.884701 5849.585084 3078.755082 3430.920328 0.819174681 0.875375156 1.027654169 0.78869711 0.830221696 1.668794931 1.639176712 1.704960921 0.897355458 1 11.74437991 -5.258110595 24.90117651 0.903898362 1.6677975 0.959760589 0.073134385 44.2965471 331360.8047 0.012578001 0.030678893 5.52E-06 5.258110595 0.763899138 QPPYQLRPSLFVLS(ph)PIKEPAK ddPTM_HeLa_Curcumin_4h_R1 1 QPPYQLRPSLFVLSPIKEPAK 21 2 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 0 QPPYQLRPSLFVLS(1)PIKEPAK 77.045 0.0011586 24857000 1548.9 1684.9 1601.7 1610.9 1560 3292.5 2284.9 1752.5 1811.6 1479.2 TRUE FALSE FALSE 1426.302931 1830.535248 1661.060411 1604.234523 1541.398019 2609.598386 2349.008145 2286.829182 1612.872012 1530.60209 0.93185743 1.19595763 1.085233335 1.048106842 1.007053387 1.704948924 1.534695503 1.494071645 1.053750039 1 10.57988356 -5.26988721 24.99999999 1.002149703 1.573584375 0.879837503 0.089050555 138.4914441 409843.425 0.013850282 0.031444377 5.37E-06 5.26988721 0.571434672 QPS(ph)DASETTGLVQR ddPTM_HeLa_Curcumin_4h_R1 2 QPSDASETTGLVQR 14 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 0 QPS(0.803)DAS(0.163)ET(0.025)T(0.008)GLVQR;QPS(0.998)DAS(0.002)ETTGLVQR ; 154.81 1.02E-06 8273500 1086.84 956.38 826.92 1059.87 917.63 1250.86 769.57 779.02 861 916.4 TRUE FALSE FALSE 1000.815467 1039.045226 857.5663826 1055.484539 906.6878616 991.4175359 791.162063 1016.539612 766.5504541 948.2448318 1.055439939 1.095756276 0.904372324 1.113092846 0.956174852 1.045529069 0.834343659 1.072022307 0.80838875 1 9.889115793 QPS(ph)DHSYALLDLDSLK ddPTM_HeLa_Curcumin_4h_R1 1 QPSDHSYALLDLDSLK 16 0 Q8WTV1;Q8WTV1-3 Q8WTV1 THAP3 THAP domain-containing protein 3 1 0 QPS(0.931)DHS(0.069)YALLDLDSLK 75.416 0.01777 5558900 1016.7 984.1 740.23 1074 1035.5 1563.3 849.91 1211.1 973.01 1001.4 TRUE FALSE FALSE 936.2271222 1069.161219 767.663575 1069.556073 1023.152339 1239.053958 873.7561872 1580.358815 866.2732374 1036.198575 0.903520951 1.031811126 0.740846005 1.032192186 0.987409521 1.19576883 0.843232376 1.525150538 0.836010836 1 10.01708479 -4.253954655 24.95708665 0.962419748 1.525150812 0.664087745 0.1220331 371.2285569 1237795.254 0.014888966 0.208524966 5.57E-05 4.253954655 0.562731064 (ac)AHS(ph)PVQSGLPGMQNLK ddPTM_HeLa_Curcumin_4h_R1 1 AHSPVQSGLPGMQNLK 16 0 B4DR80;Q9Y6E0-2 B4DR80 STK24 1 0 AHS(0.999)PVQS(0.001)GLPGMQNLK 77.062 0.0015818 23916000 1360.1 1508.3 1509.6 1551 1715.5 2095.5 1642.9 2697 1734.6 1573.7 TRUE FALSE FALSE 1252.44665 1638.670731 1565.547104 1544.582373 1695.043783 1660.869679 1688.995352 3519.302885 1544.31872 1628.385958 0.769133782 1.006315931 0.961410344 0.948535797 1.040934905 1.019948416 1.037220534 2.161221587 0.948373887 1 10.66922697 -4.238781881 3.229789798 0.924984396 2.37345602 0.953153819 0.079001255 0.0728466 1.137996857 0.015027141 0.270508342 5.77E-05 4.238781881 1.448471625 up QPS(ph)GAGLCDISEGTVVPEDR ddPTM_HeLa_Curcumin_4h_R1 2 QPSGAGLCDISEGTVVPEDR 20 0 H0Y332;Q5T5C0-3;Q5T5C0-2;Q5T5C0 H0Y332 STXBP5 Syntaxin-binding protein 5 1 0 QPS(1)GAGLCDISEGTVVPEDR;QPS(1)GAGLCDISEGTVVPEDR ; 156.2 1.51E-05 26763000 981.58 720.57 611.73 642.15 755.54 929.26 408.08 342.39 996.19 662.94 TRUE FALSE FALSE 903.8869072 782.85286 634.4012519 639.4929534 746.530679 736.5210011 419.5296265 446.7831348 886.9104493 685.9771157 1.317663354 1.141222997 0.924814017 0.93223657 1.088273445 1.073681591 0.611579624 0.651309096 1.292915506 1 9.422016638 -4.243547174 0.650629572 1.136252314 0.204993725 0.617278727 0.138673267 1.787434901 0.509298996 0.028365026 1.239912525 5.71E-05 4.243547174 -0.931258589 QPS(ph)SPSHNTNLR ddPTM_HeLa_Curcumin_4h_R1 1 QPSSPSHNTNLR 12 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 0 QPS(0.596)S(0.395)PS(0.009)HNTNLR 75.669 0.014057 7666500 774.01 597.93 533.57 447.09 873.69 1494.1 771.67 455.46 815.61 449.1 TRUE FALSE FALSE 712.7462918 649.6124049 553.3445736 445.24006 863.2718174 1184.206818 793.3209834 594.3276573 726.1396236 464.7061916 1.533756822 1.397899182 1.190740695 0.958110884 1.857672295 2.548291457 1.707145284 1.278932082 1.562577897 1 8.860175057 -10.07117437 0.100665951 2.57E-11 2.197790703 0.067711698 0.428911792 49.97083747 0.956146757 17.96233418 5.463620954 8.49E-11 10.07117437 2.197790703 QPSPS(ph)PSPTER ddPTM_HeLa_Curcumin_4h_R1 2 QPSPSPSPTER 11 0 P29590;P29590-5;P29590-4;P29590-9;P29590-3;P29590-8;P29590-11;P29590-12;H3BT57;P29590-13;P29590-14;P29590-10;P29590-2 P29590;P29590-2 PML Protein PML 1 0 QPS(0.104)PS(0.879)PS(0.017)PTER;QPS(0.021)PS(0.89)PS(0.085)PT(0.004)ER ; 130.19 0.002817 75903000 1754.48 1588.69 1589.33 1529.49 2251.1 2515.1 1902.89 1096.36 1793.91 1500.19 TRUE FALSE FALSE 1615.611057 1726.009285 1648.231968 1523.161376 2224.257103 1993.439909 1956.279972 1430.635117 1597.122561 1552.321491 1.040770914 1.111889061 1.061785189 0.981215157 1.432858539 1.284166921 1.260228621 0.921610069 1.028860691 1 10.60021166 -5.795957821 24.99950357 1.028587861 1.231499501 0.355536211 0.12305584 134.4153079 97348.08415 0.017549542 0.031812314 1.60E-06 5.795957821 0.20291164 EQS(ph)TPPKSPQ ddPTM_HeLa_Curcumin_4h_R1 1 EQSTPPKSPQ 10 1 A0A087X183;H0Y4V9;Q92615 A0A087X183 LARP4B La-related protein 4B 1 0 EQS(0.91)T(0.09)PPKSPQ 145.14 0.01103 96211000 13265 11682 11829 15317 12657 17010 10929 4247.9 16550 13059 TRUE FALSE FALSE 12215.06125 12691.74003 12267.39315 15253.62231 12506.07354 13481.93426 11235.63833 5543.065155 14734.50641 13512.79928 0.90396231 0.939238404 0.907835075 1.128827714 0.925498358 0.997715868 0.831481183 0.410208502 1.090411106 1 13.72203895 -4.277989905 2.563177253 0.961882766 0.304612791 0.841497091 0.074821625 0.119009337 1.014037448 0.009072721 0.165695651 5.27E-05 4.277989905 -0.657269975 down QPSS(ph)PSHNTNLR ddPTM_HeLa_Curcumin_4h_R1 1 QPSSPSHNTNLR 12 0 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 1 0 QPS(0.22)S(0.742)PS(0.038)HNTNLR 85.163 0.0093316 8355100 839.36 597.5 589.49 573.89 1340 2127.1 865.28 570.61 1493.8 668.3 TRUE FALSE FALSE 772.9237703 649.1452376 611.337018 571.5153952 1324.021375 1685.915483 889.557428 744.5863622 1329.933877 691.5233753 1.117711704 0.938717708 0.884043895 0.826458534 1.914644425 2.437973238 1.286373621 1.076733468 1.923194392 1 9.433634209 -5.762323546 24.99973218 1.018525667 1.705108691 0.256609417 0.451789969 16.25643483 459671.5849 0.052714908 0.099742619 1.73E-06 5.762323546 0.686583024 SSDSKPGVSSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 SSDSKPGVSSKK 12 2 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 0 1 SSDSKPGVSSK(1)K 92.906 0.0038164 1357500 1424.8 1314 1505.2 1305.8 1474.6 2309.9 2034.8 3173 1843.4 1400.2 FALSE TRUE FALSE 1312.025577 1427.576305 1560.984036 1300.396946 1457.016358 1830.800702 2091.891012 4140.433093 1641.183632 1448.856846 0.905559152 0.985312185 1.07739011 0.897533079 1.00563169 1.263617387 1.44382174 2.857724078 1.132743816 1 10.50069934 -3.011820299 0.979775894 0.961308851 20.62410492 0.97315329 0.091238508 1.561423735 0.166336065 0.011457153 56.30273984 0.00097315 3.011820299 19.66279606 up QPVSEPPADQVASDMPHS(ph)PTLR ddPTM_HeLa_Curcumin_4h_R1 1 QPVSEPPADQVASDMPHSPTLR 22 0 Q6W2J9-4;Q6W2J9-2;Q6W2J9;H7C231;H7BYY2;H7C2V9 Q6W2J9-4 BCOR BCL-6 corepressor 1 0 QPVSEPPADQVAS(0.012)DMPHS(0.717)PT(0.27)LR 81.001 0.00038336 16733000 2236.8 1957.1 1938.6 2034.1 2335.6 3406.6 2030.1 1414.7 2402.4 1746.4 TRUE FALSE FALSE 2059.75492 2126.263003 2010.446221 2025.683433 2307.749495 2700.03276 2087.059142 1846.035518 2138.862731 1807.08727 1.139820392 1.176624416 1.112534107 1.120966025 1.277054813 1.494135233 1.154929912 1.021553053 1.183596811 1 10.81945046 -8.200994236 0.392176171 0.983159018 1.228661325 0.033067931 0.129895575 1.248919981 0.453889366 0.126962318 0.059809474 6.30E-09 8.200994236 0.245502307 QQAAYYAQT(ph)SPQGMPQHPPAPQGQ ddPTM_HeLa_Curcumin_4h_R1 3 QQAAYYAQTSPQGMPQHPPAPQGQ 24 0 Q96AE4 Q96AE4 FUBP1 Far upstream element-binding protein 1 1 0 QQAAY(0.008)Y(0.008)AQT(0.561)S(0.423)PQGMPQHPPAPQGQ;QQAAY(0.001)Y(0.007)AQT(0.496)S(0.496)PQGMPQHPPAPQGQ;QQAAYY(0.001)AQT(0.551)S(0.448)PQGMPQHPPAPQGQ ;; 72.425 0.00094991 81786000 7473.8 6322.9 6907.3 7372.7 6385.2 8902.7 6676.4 5270.8 7919.7 7027.9 TRUE FALSE FALSE 6882.240844 6869.423302 7163.290614 7342.193721 6309.06066 7056.179666 6863.721815 6877.842656 7050.928724 7272.119002 0.946387269 0.94462471 0.985034845 1.00963608 0.867568402 0.970305858 0.94384069 0.945782468 0.969583793 1 12.82816009 -13.52287875 0.236912088 1.290639552 0.944913963 0.092594227 0.036006212 52.96446196 0.68912051 7.160970712 0.022968552 3.00E-14 13.52287875 -0.345725589 QQASKS(ph)PYNGVR ddPTM_HeLa_Curcumin_4h_R1 1 QQASKSPYNGVR 12 1 Q9UK58-6;Q9UK58 Q9UK58-6 CCNL1 Cyclin-L1 1 0 QQAS(0.002)KS(0.998)PYNGVR 169.58 0.0012359 4530900 1698.5 1215.8 1209.8 1216.9 1109.8 1498.2 1088.7 862.89 1377.7 1476.9 TRUE FALSE FALSE 1564.061933 1320.888335 1254.636252 1211.86479 1096.56636 1187.456432 1119.245992 1125.981189 1226.569757 1528.222165 1.023451936 0.864330046 0.820977657 0.792989932 0.717543813 0.777018197 0.732384347 0.736791557 0.802612202 1 10.57763857 -6.903379584 1.448970027 1.0130394 0.749590661 0.505782872 0.07144136 0.054588912 0.228303549 0.004875014 0.006738232 1.25E-07 6.903379584 -0.263448739 QQDGGTTGTTK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 QQDGGTTGTTKK 12 1 F5H8F7;Q9UBL3-2;Q9UBL3-3;Q9UBL3 F5H8F7 ASH2L Set1/Ash2 histone methyltransferase complex subunit ASH2 0 1 ; QQDGGTTGTTK(1)K;QQDGGTTGTTK(1)K 142.1 3.71E-05 1250410 953.06 1107.05 706.14 492.61 667.13 704.01 480.73 535.37 497.39 671.46 FALSE TRUE FALSE 877.6242953 1202.738469 732.3101696 490.5717103 659.1749105 557.9903902 494.21799 698.6018485 442.8275614 694.793185 1.263144651 1.731074074 1.053997341 0.706068685 0.948735429 0.803102854 0.711316692 1.005481723 0.637351619 1 9.440439793 -6.513898902 24.81242521 1.183688014 0.837366823 0.247231084 0.267046258 338.0087269 933960.8842 0.035443928 0.051701725 3.06E-07 6.513898902 -0.346321191 QQDPS(ph)PGSNLGGGDDLK ddPTM_HeLa_Curcumin_4h_R1 1 QQDPSPGSNLGGGDDLK 17 0 J3KTD8;Q13951-2 J3KTD8 CBFB Core-binding factor subunit beta 1 0 QQDPS(0.89)PGS(0.11)NLGGGDDLK 110.34 0.0011578 40270000 3058.1 2382.6 2503 3064.2 3015.3 3670.3 2927.7 2132.7 2720.4 2603.3 TRUE FALSE FALSE 2816.048158 2588.541327 2595.763382 3051.521152 2979.344517 2909.038407 3009.843382 2782.950412 2421.978926 2693.764481 1.045395088 0.96093825 0.963619277 1.132809187 1.106015221 1.079915645 1.117337244 1.033108288 0.899105673 1 11.395408 -6.256711921 24.99719744 1.012539146 1.095045826 0.530130712 0.050267478 242.7332194 1283488.612 0.005731748 0.009299624 5.54E-07 6.256711921 0.08250668 QQDS(ph)QPEEVMDVLEMVENVK ddPTM_HeLa_Curcumin_4h_R1 1 QQDSQPEEVMDVLEMVENVK 20 0 Q9H307 Q9H307 PNN Pinin 1 0 QQDS(1)QPEEVMDVLEMVENVK 76.909 0.0011257 0 245.47 148.86 275.95 337.12 275.31 371.04 286.99 390.61 195.38 138.37 TRUE FALSE FALSE 226.0407905 161.7267951 286.1769498 335.7250868 272.0271081 294.0821215 295.042167 509.7051909 173.9473028 143.1783472 1.578735856 1.129547856 1.99874461 2.34480348 1.899917923 2.053956672 2.060661914 3.559932076 1.214899503 1 7.161669521 -1 0.193523308 0.990425847 10.24393126 0.734418082 0.363899455 20.31577153 0.229286022 0.377749667 56.85443219 0.1 1 9.253505408 QQEAALELEELKK ddPTM_HeLa_Curcumin_4h_R1 1 QQEAALELEELKK 13 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1;C9J813 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 0 0 69.456 0.019592 1387100 679.35 442.19 460.71 480.44 581.72 152.12 53.284 237.12 405.77 561.81 FALSE FALSE TRUE 625.5787307 480.4109332 477.7843179 478.4520666 574.7833689 120.5685973 54.77900563 309.4167964 361.2580462 581.3328557 1.076111086 0.826395633 0.821877369 0.82302602 0.988733672 0.20740028 0.094230018 0.532254101 0.621430636 1 9.183220639 -5.263769786 24.94543619 0.985026869 0.259588293 0.678338481 0.179770967 55.13358888 590172.2855 0.021050525 0.049271815 5.45E-06 5.263769786 -0.725438576 QQEELLAEENQR ddPTM_HeLa_Curcumin_4h_R1 2 QQEELLAEENQR 12 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 144.7 9.00E-05 4080800 1524.58 1437.01 1281.61 1594.31 1707.12 1862.71 1349.32 1277.51 1999.69 1442.12 FALSE FALSE TRUE 1403.907884 1561.218741 1329.107594 1587.713168 1686.763709 1476.362949 1387.178288 1667.016918 1780.32901 1492.233563 0.940809749 1.046229478 0.890683354 1.063984357 1.130361728 0.989364524 0.929598638 1.117128685 1.193063241 1 10.54325765 -6.21649196 24.99880662 0.972535025 1.041146602 0 0.095865846 547.0499992 304257.5786 0.009774733 0.016209531 6.07E-07 6.21649196 0.068611578 QQELTHQEHR ddPTM_HeLa_Curcumin_4h_R1 3 QQELTHQEHR 10 0 P18206;P18206-2;P18206-3 P18206 VCL Vinculin 0 0 ;; ;; 88.134 0.006364 7958900 1854.68 2779.94 2317.92 1637.69 2053.05 2856.61 1632.59 1778.29 2165.78 2502.68 FALSE FALSE TRUE 1707.880121 3020.225626 2403.824154 1630.913673 2028.56872 2264.116885 1678.396082 2320.482435 1928.199353 2589.647944 0.65950282 1.16626881 0.928243609 0.629782004 0.783337644 0.874295246 0.648117473 0.896060965 0.744579725 1 11.33854027 -6.296588277 24.83104223 0.870928561 0.766696009 0.149657375 0.151403884 1177.736832 832013.2563 0.026807091 0.0409495 5.05E-07 6.296588277 -0.104232551 QQFHSKPVDS(ph)DS(ph)DDDPLEAFMAEVEDQAAR ddPTM_HeLa_Curcumin_4h_R1 1 QQFHSKPVDSDSDDDPLEAFMAEVEDQAAR 30 1 Q86XP3;J3KTK9 Q86XP3 DDX42 ATP-dependent RNA helicase DDX42 2 0 QQFHS(0.009)KPVDS(0.997)DS(0.993)DDDPLEAFMAEVEDQAAR 46.63 0.0081492 2920800 435.24 354.27 352.46 492.01 448.86 290.45 433.22 578.29 487.1 417.03 TRUE FALSE FALSE 400.7902947 384.8915202 365.5224777 489.974193 443.5076377 230.207396 445.3749872 754.6079589 433.6663487 431.5217615 0.928783506 0.891940001 0.847054564 1.135456509 1.027775833 0.533478069 1.032103192 1.748713567 1.004969824 1 8.753289506 -4.274804243 4.663176952 0.940493841 1.789491695 0.722793554 0.152256431 0.0663652 3.825128835 0.020149955 0.178590153 5.31E-05 4.274804243 0.848997854 QQFS(ph)PSMTER ddPTM_HeLa_Curcumin_4h_R1 1 QQFSPSMTER 10 0 Q8TDB6 Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L 1 0 QQFS(0.5)PS(0.5)MTER 105.25 0.0096509 13421000 2693.8 2294.5 2313.4 2651.3 3083.6 2963.6 2916.5 1698.3 2780.7 2297.1 TRUE FALSE FALSE 2480.582888 2492.826356 2399.136639 2640.329623 3046.830084 2348.915953 2998.329141 2216.103852 2475.664167 2376.924054 1.043610495 1.048761466 1.009345097 1.110817831 1.281837372 0.988216662 1.261432453 0.932341043 1.041541131 1 11.21488009 -6.213046009 6.034380575 1.022908924 1.125993046 0.150168131 0.100702921 0.247068192 22.20987431 0.013449487 0.022306467 6.12E-07 6.213046009 0.103084122 QQFSPS(ph)MTER ddPTM_HeLa_Curcumin_4h_R1 1 QQFSPSMTER 10 0 Q8TDB6 Q8TDB6 DTX3L E3 ubiquitin-protein ligase DTX3L 1 0 QQFS(0.192)PS(0.804)MT(0.004)ER 110.8 0.0072617 12128000 3801.3 2803.1 3637.1 3387.4 4687.7 4451.7 4566.9 2591.6 3920.4 3032.7 TRUE FALSE FALSE 3500.423094 3045.387474 3771.894126 3373.383836 4631.802239 3528.367239 4695.034923 3381.76691 3490.341928 3138.086099 1.115464325 0.970460139 1.201972797 1.074981288 1.475995907 1.124369162 1.496145987 1.077652685 1.112251805 1 11.61566922 -6.133577759 1.808663499 1.053188322 1.291337883 0.314541683 0.142305139 0.257457879 1.651239958 0.020068758 0.037819135 7.35E-07 6.133577759 0.238149562 QQGHEPVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 QQGHEPVSPR 10 0 Q9BTA9-2;Q9BTA9;A0A0A0MRT2;Q9BTA9-5 Q9BTA9-2 WAC WW domain-containing adapter protein with coiled-coil 1 0 QQGHEPVS(1)PR;QQGHEPVS(1)PR ; 84.468 0.012439 43351800 4735.4 4576.5 5354.9 5417.1 5482.2 6017.4 5106.7 4841.3 5404 4419.5 TRUE FALSE FALSE 4360.588093 4972.072268 5553.357305 5394.685476 5416.828346 4769.32341 5249.980258 6317.390083 4811.19472 4573.077296 0.953534745 1.087248683 1.214358942 1.179661993 1.184503999 1.04291336 1.148019139 1.381430856 1.052069407 1 12.15894959 -7.026384772 3.49425892 0.978461238 1.181662173 0.509535652 0.082658122 0.123157659 3.147103282 0.013192875 0.016863792 9.41E-08 7.026384772 0.203200935 QQIGSSAMPYK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 QQIGSSAMPYKR 12 1 A0A1B0GTG9;A0A1B0GWF8;A0A1B0GWJ0;A0A1B0GTJ7;A0A0A6YY92;P30566-2;P30566;A0A096LPA2;A0A096LNY6 A0A1B0GTG9 ADSL Adenylosuccinate lyase 0 1 ; QQIGSSAMPYK(1)R;QQIGSSAMPYK(1)R 91.313 0.0031233 2356800 1816.09 1806.52 2077.54 1662.58 1692.03 1986.49 1930.7 1334.27 1843.68 2225.17 FALSE TRUE FALSE 1672.34456 1962.667539 2154.53546 1655.700684 1671.853647 1574.469582 1984.870246 1741.082781 1641.432917 2302.494492 0.726318593 0.852409222 0.93573968 0.719089965 0.726105384 0.683810358 0.862052115 0.756172398 0.712893309 1 11.16898199 -9.418872352 0.880854802 1.015982919 0.780005597 0 0.115905611 0.45158489 0.555080002 0.075607885 0.014619054 3.81E-10 9.418872352 -0.235977322 QQIMQLK ddPTM_HeLa_Curcumin_4h_R1 1 QQIMQLK 7 0 H7BZL4;H7C410;P35052 H7BZL4 GPC1 Glypican-1;Secreted glypican-1 0 0 78.616 0.015974 3607000 1086.4 1490.9 1414.6 1177.2 953.85 1328.7 1629.7 838.88 1395.2 1878.8 FALSE FALSE TRUE 1000.410294 1619.766753 1467.02632 1172.329058 942.4759617 1053.112642 1675.424996 1094.65065 1242.150051 1944.08816 0.514591012 0.833175566 0.754608948 0.60302258 0.484790752 0.541700044 0.861805051 0.563066363 0.6389371 1 10.92487793 -9.448925455 1.067421269 1.009407414 0.638655048 0 0.166351732 0.353693765 0.690621611 0.102608987 0.023007156 3.56E-10 9.448925455 -0.370752366 QQLEEEEENFSRPQIDENPLDDNS(ph)EEEMEDAPK ddPTM_HeLa_Curcumin_4h_R1 3 QQLEEEEENFSRPQIDENPLDDNSEEEMEDAPK 33 1 Q5F1R6;Q5F1R6-3;Q5F1R6-2;A0A2R8Y534;A0A2R8Y4Q0;A0A2R8Y4N5 Q5F1R6 DNAJC21 DnaJ homolog subfamily C member 21 1 0 QQLEEEEENFSRPQIDENPLDDNS(1)EEEMEDAPK;QQLEEEEENFSRPQIDENPLDDNS(1)EEEMEDAPK;QQLEEEEENFSRPQIDENPLDDNS(1)EEEMEDAPK ;; 91.926 6.11E-11 52708000 12714.1 10072.5 11212.8 12582.4 11515.2 13829.6 11249.8 10944.4 12141.4 11264.4 TRUE FALSE FALSE 11707.76557 10943.12202 11628.35623 12530.33736 11377.88876 10961.18507 11565.43911 14281.29718 10809.5188 11655.83706 1.00445515 0.93885338 0.997642312 1.075026812 0.976153725 0.94040308 0.992244405 1.225248526 0.927391035 1 13.50876499 -4.260836514 24.58993239 0.99615405 1.225248615 0.741358302 0.042239811 13.40912885 546766.6289 0.004948983 0.039551827 5.48E-05 4.260836514 0.229094565 QQLLIGAYAK ddPTM_HeLa_Curcumin_4h_R1 1 QQLLIGAYAK 10 0 Q99832-3;Q99832;Q99832-2;Q99832-4 Q99832-3 CCT7 T-complex protein 1 subunit eta 0 0 141.52 2.10E-05 934890 1186.1 682.4 1045.4 976.91 923.8 1472.2 1205.5 1223.7 1108.9 918.36 FALSE FALSE TRUE 1092.218933 741.3836153 1084.143444 972.8678053 912.7842884 1166.849125 1239.323086 1596.800497 987.2564443 950.2729416 1.149373917 0.780179654 1.140875843 1.023777236 0.960549594 1.22790945 1.304175918 1.680359849 1.038918821 1 9.89219814 -4.245722723 1.203998722 1.045838472 1.985138087 0.786042924 0.106576125 0.561160562 0.649470158 0.016241119 0.662666531 5.68E-05 4.245722723 0.939299616 QQLS(ph)AEELDAQLDAYNAR ddPTM_HeLa_Curcumin_4h_R1 1 QQLSAEELDAQLDAYNAR 18 0 Q86V81;E9PB61 Q86V81 ALYREF THO complex subunit 4 1 0 QQLS(1)AEELDAQLDAYNAR 122.64 0.00030614 15986000 1891.4 1530.5 1676.1 1548.9 1712.5 2183.1 1643.2 2150.8 2021.3 1920.2 TRUE FALSE FALSE 1741.693694 1662.7896 1738.21774 1542.491062 1692.079556 1730.300451 1689.30377 2806.569019 1799.568447 1986.926807 0.876576675 0.836865049 0.874827263 0.776320022 0.851606385 0.870842572 0.85020936 1.412517567 0.905704448 1 10.95632301 -4.257836609 24.98859662 0.902847554 1.412517761 0.871010649 0.061404993 122.2553857 847918.572 0.011337328 0.111938916 5.52E-05 4.257836609 0.509670207 AS(ph)PATPAGHPVSGLLLR ddPTM_HeLa_Curcumin_4h_R1 1 ASPATPAGHPVSGLLLR 17 0 A0A3B3IRR3;Q9HCM7 A0A3B3IRR3 FBRSL1 Fibrosin-1-like protein 1 0 AS(0.997)PAT(0.003)PAGHPVSGLLLR 70.02 0.0092403 23070000 1227.6 882.07 910.3 831.56 999.37 1426.1 914.81 365.83 1258.5 947.79 TRUE FALSE FALSE 1130.434165 958.3122004 944.0365188 828.1192251 987.4531655 1130.310785 940.4771065 477.3698829 1120.445699 980.725632 1.15265078 0.977146073 0.962589829 0.844394393 1.006859751 1.152524975 0.958960463 0.486751715 1.142466009 1 9.937705774 -4.276667498 3.654306776 1.042734757 0.433816799 0.747811707 0.093706538 0.101909732 2.498650213 0.01433939 0.164430394 5.29E-05 4.276667498 -0.608917958 down QQLSAEELDAQLDAYNAR ddPTM_HeLa_Curcumin_4h_R1 1 QQLSAEELDAQLDAYNAR 18 0 Q86V81;E9PB61 Q86V81 ALYREF THO complex subunit 4 0 0 202.32 3.75E-34 0 905.74 763.74 988.55 1115.9 1039.4 1105.9 990.7 1041.3 1012.2 871.29 FALSE FALSE TRUE 834.0497233 829.7542824 1025.186533 1111.282701 1027.005834 876.5238739 1018.496376 1358.787576 901.1641924 901.5672626 0.925110924 0.920346509 1.13711597 1.232612083 1.139133902 0.972222385 1.129695385 1.507139437 0.999552923 1 9.81629132 -6.676332116 5.166773224 0.960459168 1.17713937 0.426772501 0.128102968 0.160349185 7.294013989 0.020122012 0.028500672 2.11E-07 6.676332116 0.216680202 QQLSPS(ph)PGQEAGILPETEK ddPTM_HeLa_Curcumin_4h_R1 1 QQLSPSPGQEAGILPETEK 19 0 E5RJM0;B7ZLQ8;Q17RY0-2;Q17RY0 E5RJM0 CPEB4 Cytoplasmic polyadenylation element-binding protein 4 1 0 QQLS(0.063)PS(0.937)PGQEAGILPETEK 148.36 9.18E-05 4757700 4379.5 3430.8 3129.6 3495.9 3499.4 4352.8 3266.8 5149.3 4077.2 3446.5 TRUE FALSE FALSE 4032.857954 3727.343065 3245.585729 3481.434892 3457.671941 3449.980214 3358.457616 6719.297866 3629.941361 3566.265618 1.130834992 1.04516698 0.91007964 0.97621301 0.96954975 0.967392949 0.941729522 1.884127147 1.01785502 1 11.80019844 -4.257945512 24.99600746 1.027563791 1.884127469 0.942723057 0.065285512 71.66438156 512681.9492 0.011564133 0.112900817 5.52E-05 4.257945512 0.856563678 QQPGPSEHIER ddPTM_HeLa_Curcumin_4h_R1 1 QQPGPSEHIER 11 0 P50552;K7EQD0 P50552 VASP Vasodilator-stimulated phosphoprotein 0 0 77.597 0.014816 334930 0 0 0 79.314 0 128.03 0 158.36 134.78 0 FALSE FALSE TRUE 0 0 0 78.98581968 0 101.4751348 0 206.643235 119.9949712 0 0 QQPPEPEWIGDGES(ph)TSPSDKVVK ddPTM_HeLa_Curcumin_4h_R1 2 QQPPEPEWIGDGESTSPSDKVVK 23 1 Q5STZ8;Q8NE71;Q8NE71-2;A0A0G2JIC2 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 0 QQPPEPEWIGDGES(0.307)T(0.307)S(0.307)PS(0.079)DKVVK;QQPPEPEWIGDGES(0.401)T(0.401)S(0.187)PS(0.01)DKVVK ; 121.94 2.24E-06 123605000 9579.2 6894.4 8380 8992.1 8519.1 10789.4 7703.6 5391 10961.5 8399.4 TRUE FALSE FALSE 8820.996212 7490.321215 8690.570172 8954.893073 8417.515297 8551.556818 7919.742283 7034.691083 9759.050874 8691.278525 1.014925041 0.861820409 0.999918498 1.030330929 0.968501386 0.983923918 0.911228683 0.809396576 1.122855613 1 13.0853527 -4.283297508 1.393218853 0.995439048 0.734176409 0.493692412 0.060362033 0.608117857 1.059482615 0.00667196 0.219404822 5.21E-05 4.283297508 -0.26126264 QQPPEPEWIGDGES(ph)TSPSDKVVKK ddPTM_HeLa_Curcumin_4h_R1 2 QQPPEPEWIGDGESTSPSDKVVKK 24 2 Q5STZ8;Q8NE71;Q8NE71-2;A0A0G2JIC2 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 0 QQPPEPEWIGDGES(0.834)T(0.079)S(0.079)PS(0.009)DKVVKK;QQPPEPEWIGDGES(0.319)T(0.319)S(0.319)PS(0.042)DKVVKK ; 55.988 0.0026119 21423200 5802 4177.3 3953.3 5127.9 3895.3 6217.6 4241.3 3264.9 6968.4 5774.6 TRUE FALSE FALSE 5342.765578 4538.367198 4099.812776 5106.682109 3848.851092 4927.999673 4360.299463 4260.35298 6203.983954 5975.26692 0.894146764 0.759525434 0.686130483 0.854636651 0.644130403 0.824732977 0.729724633 0.712997936 1.038277292 1 12.54478745 -7.562253206 1.052006444 0.972704639 0.739872379 0.733588833 0.064994378 0.160916245 0.363507358 0.013688449 0.013994933 2.74E-08 7.562253206 -0.232832259 QQPPEPEWIGDGEST(ph)SPSDKVVK ddPTM_HeLa_Curcumin_4h_R1 1 QQPPEPEWIGDGESTSPSDKVVK 23 1 Q5STZ8;Q8NE71;Q8NE71-2;A0A0G2JIC2 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 0 QQPPEPEWIGDGES(0.137)T(0.768)S(0.093)PS(0.002)DKVVK 115.79 3.63E-06 39655000 5098.3 3294.9 4002.1 4429.4 4155.9 5361.8 3975 2545.1 4922.2 4466.8 TRUE FALSE FALSE 4694.764175 3579.696474 4150.421347 4411.072316 4106.343607 4249.70224 4086.527802 3321.089274 4382.246975 4622.020968 1.015738398 0.774487286 0.897966793 0.954360083 0.888430329 0.919446768 0.884143069 0.718536177 0.94812356 1 12.17430809 -1 0.175103773 1.034724102 0.004388412 0.32367263 0.072685752 37.57375987 0.401585457 0.102191159 10.28126951 0.1 1 -1.03033569 QQPPEPEWIGDGESTS(ph)PSDK ddPTM_HeLa_Curcumin_4h_R1 2 QQPPEPEWIGDGESTSPSDK 20 0 Q5STZ8;Q8NE71;Q8NE71-2;A0A0G2JIC2 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 0 QQPPEPEWIGDGEST(0.239)S(0.749)PS(0.012)DK;QQPPEPEWIGDGEST(0.02)S(0.973)PS(0.007)DK ; 190.61 1.50E-10 72085000 13138.9 10376.8 12030.3 12180.3 14002.2 13940.1 11841.8 7464.7 11833.7 10610.1 TRUE FALSE FALSE 12098.9422 11273.72435 12476.1535 12129.90115 13835.23291 11048.76612 12174.04904 9740.652667 10535.57272 10978.80019 1.102027726 1.02686306 1.136385879 1.10484761 1.26017713 1.006372822 1.108868805 0.887223786 0.959628788 1 13.42243278 -4.254167258 24.40287685 1.071694858 0.887223663 0.326199186 0.081906901 586.9037553 1969389.051 0.010889338 0.149300344 5.57E-05 4.254167258 -0.184471195 QQPPEPEWIGDGESTS(ph)PSDKVVK ddPTM_HeLa_Curcumin_4h_R1 1 QQPPEPEWIGDGESTSPSDKVVK 23 1 Q5STZ8;Q8NE71;Q8NE71-2;A0A0G2JIC2 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 0 QQPPEPEWIGDGES(0.01)T(0.01)S(0.918)PS(0.063)DKVVK 101.48 2.01E-05 274920000 4388.3 3214.6 3910.8 4330.5 4234.2 5300.8 3811 2803.6 4594.6 3623.6 TRUE FALSE FALSE 4040.961424 3492.4557 4055.737688 4312.581538 4183.70993 4201.354328 3917.926403 3658.404734 4090.583875 3749.51983 1.077727711 0.931440787 1.081668553 1.150169017 1.115798854 1.120504629 1.04491417 0.975699529 1.090962059 1 11.87249014 -10.1936982 0.359643003 0.945385274 1.072588061 0 0.068912081 8.918241825 0.898077659 0.482932171 0.02430022 6.40E-11 10.1936982 0.127202786 QQPPEPEWIGDGESTS(ph)PSDKVVKK ddPTM_HeLa_Curcumin_4h_R1 1 QQPPEPEWIGDGESTSPSDKVVKK 24 2 Q5STZ8;Q8NE71;Q8NE71-2;A0A0G2JIC2 Q5STZ8 ABCF1 ATP-binding cassette sub-family F member 1 1 0 QQPPEPEWIGDGES(0.032)T(0.377)S(0.575)PS(0.017)DKVVKK 79.341 7.79E-05 102220000 2643.2 2001.2 2153.2 2726.4 1687.9 2760.6 2082.8 1475.3 3007.7 2320.6 TRUE FALSE FALSE 2433.987931 2174.174811 2232.999486 2715.118879 1667.772895 2188.020442 2141.237762 1925.112179 2677.762835 2401.240677 1.013637639 0.905438106 0.929935723 1.130715011 0.694546328 0.911204138 0.891721427 0.801715628 1.115158035 1 11.2295643 -5.763574096 24.9999998 0.999564949 0.835749164 0.534755626 0.086250443 33.18680741 388663.3479 0.01083922 0.020369076 1.72E-06 5.763574096 -0.163815785 QQPPLGPSSS(ph)LLSLPGLK ddPTM_HeLa_Curcumin_4h_R1 2 QQPPLGPSSSLLSLPGLK 18 0 Q4KMP7;Q4KMP7-2 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 0 QQPPLGPS(0.02)S(0.226)S(0.753)LLS(0.001)LPGLK;QQPPLGPS(0.003)S(0.106)S(0.888)LLS(0.003)LPGLK ; 189.44 8.13E-09 117446000 7195.5 7415.6 6199.8 6722.6 6639.6 9009.5 9031 13824.3 8131.2 8784.8 TRUE FALSE FALSE 6625.968582 8056.571421 6429.570042 6694.783662 6560.427106 7140.828142 9284.385554 18039.26543 7239.227703 9090.071146 0.728923732 0.88630455 0.707317901 0.736494088 0.721713505 0.785563504 1.021376555 1.984502117 0.796388454 1 13.15007587 -4.261800837 3.005487215 0.834245054 2.172002127 0.936904539 0.091820298 0.089621907 1.178042835 0.017447641 0.28598155 5.47E-05 4.261800837 1.337757073 QQQEK(ac)EMK ddPTM_HeLa_Curcumin_4h_R1 3 QQQEKEMK 8 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 0 1 ;; QQQEK(1)EMK;QQQEK(1)EMK;QQQEK(1)EMK 171.36 1.80E-09 8354930 2618.36 2177.77 2569.7 2287.8 2454.21 3070.81 2758.8 3154.894 2842.99 2261.1 FALSE TRUE FALSE 2411.114043 2366.006735 2664.935343 2278.33369 2424.945149 2433.889391 2836.204503 4116.806657 2531.12111 2339.673057 1.030534602 1.011255281 1.139020401 0.973782932 1.036446157 1.040269017 1.212222577 1.75956493 1.08182684 1 11.19209123 -4.211799513 1.92823127 1.022222028 2.04948281 0.957361854 0.045596132 0.107220198 0.371937017 0.005732986 0.204021609 6.14E-05 4.211799513 1.027260782 QQQLEEEAAKPPEPEKPVS(ph)PPPVEQK ddPTM_HeLa_Curcumin_4h_R1 1 QQQLEEEAAKPPEPEKPVSPPPVEQK 26 2 A0A088AWL3;O75376-2;O75376;E7EVU5;E7EW50;J3KS51;O75376-3 A0A088AWL3 NCOR1 Nuclear receptor corepressor 1 1 0 QQQLEEEAAKPPEPEKPVS(1)PPPVEQK 73.127 0.00012126 8002300 2059.9 1783.3 1883 1656.1 1737.1 1961.3 1938.3 1139.8 2212.2 1742.9 TRUE FALSE FALSE 1896.856741 1937.440506 1952.785636 1649.247497 1716.386217 1554.504272 1992.683481 1487.319773 1969.527195 1803.465645 1.051784239 1.074287448 1.082796138 0.914487892 0.951715505 0.861953914 1.104919013 0.824700918 1.092079131 1 10.81655623 -6.251863503 24.67350891 1.033583057 0.938440006 0.400741133 0.074974382 531.7606117 1370151.036 0.010248391 0.016852545 5.60E-07 6.251863503 -0.095143051 QQS(ph)PQEPK ddPTM_HeLa_Curcumin_4h_R1 2 QQSPQEPK 8 0 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 QQS(1)PQEPK;QQS(1)PQEPK ; 108.47 0.011742 318621000 12449.1 16174.5 15235 11388.6 14543.6 14342 12481 14393.5 10745.9 11716.5 TRUE FALSE FALSE 11463.7406 17572.55171 15799.6225 11341.47699 14370.17707 11367.30753 12831.18327 18782.01189 9567.101655 12123.6475 0.945568617 1.449444295 1.303207017 0.935483895 1.185301459 0.937614487 1.058359975 1.549204716 0.789127336 1 13.56553619 -1 0.170350862 0.948673898 2.269399692 0.206373904 0.210018374 83.8938793 0.882247176 0.31399164 28.40616353 0.1 1 1.320725794 QQSAS(ph)YIPK ddPTM_HeLa_Curcumin_4h_R1 1 QQSASYIPK 9 0 O95835 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 0 QQS(0.041)AS(0.556)Y(0.403)IPK 75.378 0.018181 31667000 908.81 627.88 785.38 574.48 955.87 720.34 569.77 807.35 839.21 719.29 TRUE FALSE FALSE 836.8767295 682.1511494 814.4868737 572.102954 944.4718745 570.9333641 585.7562127 1053.507298 747.1507626 744.285274 1.124403181 0.916518401 1.094320823 0.768660854 1.268964882 0.767089427 0.787004974 1.415461699 1.003849987 1 9.539711882 -7.265472887 24.62144979 1.058745943 0.990004007 0.003548123 0.206345194 1011.807676 6176298.107 0.03236301 0.037723608 5.43E-08 7.265472887 -0.068741936 QQSHFAMMHGGT(ph)GFAGIDSSSPEVK ddPTM_HeLa_Curcumin_4h_R1 1 QQSHFAMMHGGTGFAGIDSSSPEVK 25 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 0 QQS(0.007)HFAMMHGGT(0.826)GFAGIDS(0.045)S(0.045)S(0.078)PEVK 54.582 0.0023738 9693800 1592.4 1405.9 1406.3 1287.9 1800.1 3237.7 1809.9 1490.7 2116.8 1497.2 TRUE FALSE FALSE 1466.35986 1527.419731 1458.418715 1282.571011 1778.634983 2566.164524 1860.680923 1945.207568 1884.592336 1549.227589 0.946510294 0.9859234 0.94138442 0.827877725 1.148078563 1.656415457 1.201037818 1.255598327 1.216472228 1 10.59733338 -5.519090182 17.31363797 0.964118837 1.362058575 0.584563499 0.144478763 1.130363335 5162.802349 0.016359944 0.033640246 3.03E-06 5.519090182 0.397939738 QQSHFAMMHGGTGFAGIDS(ph)SSPEVK ddPTM_HeLa_Curcumin_4h_R1 3 QQSHFAMMHGGTGFAGIDSSSPEVK 25 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 0 QQSHFAMMHGGTGFAGIDS(0.419)S(0.326)S(0.255)PEVK;QQSHFAMMHGGT(0.004)GFAGIDS(0.332)S(0.332)S(0.332)PEVK;QQSHFAMMHGGT(0.025)GFAGIDS(0.464)S(0.355)S(0.156)PEVK ;; 85.19 3.87E-05 60413000 4537.4 4644.5 4169.4 4009.1 4475.2 7828.6 5266.8 3195.47 5245 3926.3 TRUE FALSE FALSE 4178.260002 5045.949885 4323.921632 3992.511406 4421.836163 6204.860113 5414.572233 4169.754093 4669.636622 4062.738633 1.028434359 1.242007016 1.064287423 0.982714314 1.088388046 1.52726047 1.332739495 1.02634072 1.1493815 1 11.98823684 -5.497256438 23.43167923 1.03512482 1.300617629 0.316407408 0.137243317 227.3325942 207895.5544 0.01851441 0.041211294 3.18E-06 5.497256438 0.265492809 QQSHFAMMHGGTGFAGIDSSS(ph)PEVK ddPTM_HeLa_Curcumin_4h_R1 1 QQSHFAMMHGGTGFAGIDSSSPEVK 25 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 0 QQSHFAMMHGGT(0.004)GFAGIDS(0.296)S(0.228)S(0.471)PEVK 78.025 9.63E-05 38283000 1186.9 1070.1 1018.4 1034.5 964.9 1890.3 1299.3 763.59 1249.2 910.76 TRUE FALSE FALSE 1092.955613 1162.594676 1056.1428 1030.219513 953.3941977 1498.230472 1335.754861 996.4050759 1112.165885 942.4088422 1.159746772 1.233641519 1.120684307 1.093176833 1.011656677 1.589788216 1.417383625 1.057295975 1.180130996 1 9.880209265 -8.67843409 0.049323211 0.29142819 1.889611949 0.07044877 0.170848519 100.6935319 1.768944156 32.75689731 24.43318532 2.10E-09 8.67843409 1.598183759 NSVAGSNPAKPGLGS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 1 NSVAGSNPAKPGLGSPGR 18 1 Q86XL3;Q86XL3-3 Q86XL3 ANKLE2 Ankyrin repeat and LEM domain-containing protein 2 1 0 NSVAGSNPAKPGLGS(1)PGR 74.561 0.0045183 10604000 1413.2 1258.9 1638 1528.8 1708.9 2090.4 1346.6 567.53 1800 1524.8 TRUE FALSE FALSE 1301.343729 1367.713706 1698.705721 1522.474231 1688.522484 1656.827476 1384.381972 740.5672844 1602.544503 1577.786687 0.824790664 0.866855905 1.076638392 0.964943008 1.070184264 1.050095992 0.877420239 0.469370981 1.015691485 1 10.62368645 -4.276428688 3.812250426 0.94535632 0.428405704 0.754607113 0.085562525 0.108487545 3.054983077 0.014034893 0.152906434 5.29E-05 4.276428688 -0.516950616 down KVSSSSPQSGCPS(ph)PTIPAGK ddPTM_HeLa_Curcumin_4h_R1 1 KVSSSSPQSGCPSPTIPAGK 20 1 E7EWD6;Q76L83;A0A5F9ZHC8 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 0 KVSSSSPQSGCPS(0.812)PT(0.188)IPAGK 84.249 0.0012518 0 1242.8 960.1 955.44 1192.8 1089.1 1295.8 983.25 92.561 1337.7 1226.2 TRUE FALSE FALSE 1144.431069 1043.086766 990.8494469 1187.86451 1076.113194 1027.036473 1010.837349 120.7824228 1190.957657 1268.810359 0.901971726 0.822098242 0.78092793 0.936203351 0.848127686 0.809448367 0.796681192 0.09519344 0.938641184 1 10.30926074 -4.276324819 2.88049116 0.913316884 5.12E-22 0.914645586 0.070825208 0.094163638 1.116065534 0.012430074 0.196295361 5.29E-05 4.276324819 -0.913316884 down SGS(ph)IVELIAGGGSSCSPVLSR ddPTM_HeLa_Curcumin_4h_R1 1 SGSIVELIAGGGSSCSPVLSR 21 0 P42858 P42858 HTT Huntingtin 1 0 S(0.082)GS(0.918)IVELIAGGGSSCSPVLSR 108.12 5.09E-05 7749600 232.29 260.5 193.67 142.68 281.61 377.57 358.13 878.34 397.14 323.63 TRUE FALSE FALSE 213.9040014 283.0164592 200.8475806 142.089628 278.2519847 299.2577259 368.1781639 1146.141823 353.5747356 334.8761184 0.638755616 0.84513778 0.599766808 0.424305049 0.830910206 0.893637108 1.099445866 3.422584531 1.055837416 1 8.387483684 -4.238644594 2.98824426 0.786914928 3.938705736 0.949906773 0.18047674 0.069825502 0.860331755 0.027389022 0.536649067 5.77E-05 4.238644594 3.151790807 up QQSTSSDRVSQT(ph)PESLDFLKVPDQGAAGVR ddPTM_HeLa_Curcumin_4h_R1 1 QQSTSSDRVSQTPESLDFLKVPDQGAAGVR 30 2 Q12965 Q12965 MYO1E Unconventional myosin-Ie 1 0 QQS(0.002)T(0.011)S(0.022)S(0.022)DRVS(0.022)QT(0.46)PES(0.46)LDFLKVPDQGAAGVR 55.049 0.0013451 14843000 532.64 482.43 502.82 328.74 550 952.18 819.09 676.68 592 436.55 TRUE FALSE FALSE 490.480982 524.1290995 521.4549515 327.379761 543.4416092 754.6871347 842.0714609 882.9966169 527.0590811 451.72008 1.085807348 1.160296216 1.154376293 0.724740333 1.203049484 1.670696451 1.864144408 1.954742895 1.166782493 1 8.819285236 -5.199954284 2.466475823 1.038789775 1.897984055 0.888289832 0.125903929 0.061527398 0.725192574 0.017285509 0.052061458 6.31E-06 5.199954284 0.85919428 QQTEKPES(ph)EDEWER ddPTM_HeLa_Curcumin_4h_R1 4 QQTEKPESEDEWER 14 1 A2AB15;A0A140T947;O60231 A2AB15 DHX16 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 1 0 QQT(0.001)EKPES(0.999)EDEWER;QQTEKPES(1)EDEWER;QQTEKPES(1)EDEWER;QQTEKPES(1)EDEWER ;;; 149.59 0.0049045 803719400 12746.5 10839.2 12163.6 12386.5 13210.8 13452.8 12496.27 11857.85 11219.1 10878.69 TRUE FALSE FALSE 11737.60107 11776.09215 12614.39372 12335.24794 13053.26984 10662.53764 12846.8817 15473.25388 9988.392799 11256.72367 1.042719127 1.046138512 1.120609699 1.095811562 1.159597608 0.947215011 1.141262954 1.374578815 0.887326818 1 13.45849936 -4.341376353 3.081339795 1.04096925 1.399342915 0.63874182 0.076602975 0.118161245 1.754425363 0.008688653 0.091505885 4.56E-05 4.341376353 0.358373664 QQTEKPES(ph)EDEWERTER ddPTM_HeLa_Curcumin_4h_R1 1 QQTEKPESEDEWERTER 17 2 A2AB15;A0A140T947;O60231 A2AB15 DHX16 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 1 0 QQTEKPES(1)EDEWERTER 87.356 0.0040679 63776000 2024.3 1415.6 1691.9 1955.3 1378.9 1993.1 1562.5 1475.6 2448.3 2034.6 TRUE FALSE FALSE 1864.074519 1537.958156 1754.603302 1947.209487 1362.457518 1579.708593 1606.339545 1925.503647 2179.727615 2105.302199 0.885418977 0.730516577 0.833421113 0.924907354 0.64715532 0.750347667 0.762997134 0.914597272 1.035351417 1 11.03981162 -8.002290592 0.633953533 0.991796075 0.78489322 0.512124419 0.082959833 0.405982368 0.369792223 0.03417506 0.022819696 9.95E-09 8.002290592 -0.206902854 S(ph)GAQASSTPLS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 S(0.993)GAQAS(0.003)S(0.003)T(0.004)PLS(0.931)PT(0.066)R 168.62 0.00049474 51796000 5021.8 4050.8 3109.8 4124.2 3921.9 6269.2 3752.4 961.55 4808.2 4036.4 TRUE FALSE FALSE 4624.319231 4400.933102 3225.051924 4107.135153 3875.133904 4968.897252 3857.682245 1254.722169 4280.75249 4176.6646 1.107179933 1.053695598 0.772159662 0.983352878 0.927805863 1.189680697 0.923627491 0.30041248 1.024921295 1 12.02813558 -4.275960695 3.807437976 1.026697832 0.237355056 0.797426873 0.105763725 0.076958374 2.158629019 0.015127511 0.165626344 5.30E-05 4.275960695 -0.789342776 down QQVEQSSAS(ph)QTGIK ddPTM_HeLa_Curcumin_4h_R1 1 QQVEQSSASQTGIK 14 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 0 QQVEQS(0.072)S(0.011)AS(0.916)QT(0.001)GIK 192.78 5.16E-06 5748900 2473.1 1585.3 1991 2552.6 2048.7 2862.2 2236.5 2043.8 2157.9 2240 TRUE FALSE FALSE 2277.351525 1722.326268 2064.788211 2542.038018 2024.270591 2268.547456 2299.250171 2666.945212 1921.183769 2317.839833 0.982531878 0.743073893 0.890824371 1.096727212 0.873343603 0.978733484 0.991979747 1.150616696 0.828868217 1 11.17856516 -4.232071622 2.67714024 0.965114976 1.195355556 0.251183211 0.10041576 0.570116669 5.012524195 0.012939336 0.299956693 5.86E-05 4.232071622 0.23024058 QQVSWEQEFLVGSS(ph)PGGSGR ddPTM_HeLa_Curcumin_4h_R1 1 QQVSWEQEFLVGSSPGGSGR 20 0 Q9BUA3 Q9BUA3 C11orf84 Uncharacterized protein C11orf84 1 0 QQVSWEQEFLVGS(0.04)S(0.959)PGGS(0.001)GR 183.39 8.96E-08 11500000 2449.7 2238.6 2844.3 2264.6 3127.6 3131.1 2906.7 2618.1 2291 2123.5 TRUE FALSE FALSE 2255.80366 2432.094609 2949.71226 2255.229685 3090.305413 2481.674565 2988.254179 3416.346638 2039.683032 2197.291467 1.026629236 1.106860262 1.342431036 1.026368017 1.406415789 1.129424386 1.359971685 1.554799028 0.928271494 1 11.10151054 -1 0.217990671 0.968638502 3.8009478 0.652785313 0.117946026 20.6937565 0.246641711 0.082417307 20.75208572 0.1 1 2.832309298 QREEEIEAQEK ddPTM_HeLa_Curcumin_4h_R1 1 QREEEIEAQEK 11 1 O75937;S4R3J5 O75937 DNAJC8 DnaJ homolog subfamily C member 8 0 0 176.32 4.30E-10 1671600 1407 916.74 1324.1 1150.8 885.37 1824.8 863.21 1304.6 1179 1256.7 FALSE FALSE TRUE 1295.634465 995.9789207 1373.172311 1146.038295 874.812541 1446.31591 887.4293494 1702.366534 1049.66665 1300.370231 0.99635814 0.765919502 1.055985655 0.881316926 0.672741132 1.112233943 0.682443606 1.309139884 0.807205997 1 10.34470672 -7.458851197 24.99853058 0.998394226 0.914512161 0 0.196694168 528.1440189 206205.6959 0.028281388 0.032338716 3.48E-08 7.458851197 -0.083882066 QRELAEQELEK ddPTM_HeLa_Curcumin_4h_R1 1 QRELAEQELEK 11 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 127.87 0.00051488 2090200 1143.4 997.11 812.65 1265.6 956.61 1254.6 943.73 1080.7 1187.5 1075 FALSE FALSE TRUE 1052.898683 1083.295745 842.7675239 1260.363283 945.2030505 994.3818177 970.2085239 1410.200455 1057.234221 1112.35617 0.946548158 0.973874892 0.757641794 1.133057304 0.849730577 0.893941927 0.872210314 1.267759818 0.950445774 1 10.11940309 -4.252358231 24.48521482 0.951458062 1.267760038 0.512979815 0.096624946 555.1657873 1496832.981 0.012459397 0.200315277 5.59E-05 4.252358231 0.316301976 QRELEIEER ddPTM_HeLa_Curcumin_4h_R1 1 QRELEIEER 9 1 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 88.134 0.018856 6663100 1934.3 1280.1 1804 1761.2 1678.5 1995.8 1376.2 1690.4 1869.7 1699.1 FALSE FALSE TRUE 1781.198114 1390.74614 1870.857827 1753.912621 1658.484984 1581.848583 1414.812468 2205.795178 1664.598588 1758.143599 1.013112988 0.791031029 1.064109797 0.997593497 0.943315998 0.899726612 0.804719517 1.254616051 0.946793305 1 10.77983719 QRLEAEAGR ddPTM_HeLa_Curcumin_4h_R1 3 QRLEAEAGR 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ;; ;; 131.52 0.0031738 12238370 3811.72 2981.67 3323.92 3203.72 3340.98 3944.57 3343.19 3104.49 3427.49 3776.85 FALSE FALSE TRUE 3510.01834 3239.392269 3447.107399 3190.463856 3301.140996 3126.421718 3436.990914 4051.03471 3051.502922 3908.095256 0.898140426 0.828892864 0.88204283 0.816373104 0.844693074 0.799986058 0.879454232 1.036575222 0.780815902 1 11.93224992 -8.526198273 0.756567049 0.993700684 0.865386916 0 0.091094439 0.466932154 0.550196382 0.029807126 0.014086352 2.98E-09 8.526198273 -0.128313768 QRLQDIS(ph)S(ph)LPLPQS(ph)LKNY(ph)LQYQ ddPTM_HeLa_Curcumin_4h_R1 1 QRLQDISSLPLPQSLKNYLQYQ 22 2 Q96A44 Q96A44 SPSB4 SPRY domain-containing SOCS box protein 4 4 0 QRLQDIS(1)S(1)LPLPQS(0.991)LKNY(0.782)LQY(0.228)Q 48.286 0.0074634 0 1751 1718.6 1817.2 1853.9 1266.7 1153.6 1438.1 1536.7 2038.7 2320.5 TRUE FALSE FALSE 1612.406502 1867.148126 1884.547031 1846.229053 1251.59543 914.3303562 1478.449216 2005.232756 1815.059711 2401.137202 0.671517854 0.777609928 0.784856038 0.768897775 0.521251109 0.38079055 0.615728753 0.835117941 0.7559167 1 11.22950213 -11.93542726 0.202006507 1.811539353 0.583099753 0.18047585 0.148714957 17.38448164 0.374030776 5.929308922 0.153135698 1.16E-12 11.93542726 -1.2284396 QRNK(ac)QVAMGRK ddPTM_HeLa_Curcumin_4h_R1 1 QRNKQVAMGRK 11 3 K7ENH6;K7EKA2;Q15438-3 K7ENH6 CYTH1 0 1 QRNK(1)QVAMGRK 109.71 0.0032709 6699400 1804.3 1795.2 1459.3 1535.3 1389.5 2300 1495.3 1120.5 2072.1 1613.8 FALSE TRUE FALSE 1661.487751 1950.369089 1513.382942 1528.947335 1372.93112 1822.954074 1537.254094 1462.135292 1844.795814 1669.87943 0.99497468 1.167970007 0.906282762 0.915603431 0.822173802 1.091668082 0.920577897 0.875593331 1.104747912 1 10.70552822 QRPDLGS(ph)AQK ddPTM_HeLa_Curcumin_4h_R1 1 QRPDLGSAQK 10 1 A0A3B3ITP6;A0A3B3IT92;P33991;A0A3B3IS57;A0A3B3IU45;E5RFR3 A0A3B3ITP6 MCM4 DNA replication licensing factor MCM4 1 0 QRPDLGS(1)AQK 111.31 0.0030782 141520000 5133.1 4643.3 4239.7 4284.8 5159 6614.3 6234 1836.8 4690 4858.4 TRUE FALSE FALSE 4726.809719 5044.646162 4396.827012 4267.070633 5097.482294 5242.419621 6408.909262 2396.831864 4175.518734 5027.229038 0.940241569 1.003464557 0.874602485 0.84879177 1.013974549 1.042805009 1.274839323 0.476769975 0.830580565 1 12.2955477 -1.000249069 0.008366231 1.809988213 3.77E-06 0 0.195060035 87752.20947 57.3592921 5486.329609 7011.77594 0.099942666 1.000249069 -1.809984441 QRPSYDIFEDS(ph)DDS(ph)EPGGPPAPR ddPTM_HeLa_Curcumin_4h_R1 2 QRPSYDIFEDSDDSEPGGPPAPR 23 1 A0A669KBI7;Q9UMN6 A0A669KBI7 KMT2B Histone-lysine N-methyltransferase 2B 2 0 QRPSYDIFEDS(1)DDS(1)EPGGPPAPR;QRPSYDIFEDS(1)DDS(1)EPGGPPAPR ; 97.295 7.11E-05 10358000 2411.6 1689.67 1801.8 2012.32 1903.8 2347.9 2103.1 1550.68 2161 2016.65 TRUE FALSE FALSE 2220.719315 1835.717546 1868.576293 2003.993553 1881.098428 1860.919074 2162.107326 2023.475194 1923.943707 2086.728437 1.06421098 0.879710801 0.895457339 0.960351868 0.901458184 0.891787853 1.036122999 0.969687841 0.921990457 1 11.02702715 -7.269006054 24.97101971 1.030321852 0.934188803 0.115746617 0.057858417 393.6387039 1299056.54 0.008716398 0.010068398 5.38E-08 7.269006054 -0.096133049 QRPVPQPSSASLDEYT(ph)LMR ddPTM_HeLa_Curcumin_4h_R1 2 QRPVPQPSSASLDEYTLMR 19 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 QRPVPQPSSAS(0.003)LDEY(0.439)T(0.558)LMR;QRPVPQPSSAS(0.004)LDEY(0.438)T(0.558)LMR ; 72.187 0.0049836 109090000 4299.6 3604.4 3692.3 3537.4 4086.7 4617.8 3704.3 1873.74 3927.7 3823.3 TRUE FALSE FALSE 3959.282123 3915.948275 3829.139886 3522.763176 4037.968772 3660.016227 3808.232688 2445.0347 3496.841137 3956.15939 1.000789334 0.98983582 0.967893229 0.890450265 1.02067899 0.925143773 0.962608508 0.618032404 0.88389794 1 11.94988484 -3.86913561 1.669049482 0.98825912 5.86E-13 0.782700441 0.052135296 0.771943815 0.861801502 0.005726594 1.693793587 0.000135165 3.86913561 -0.98825912 QRQPPGTQQSHS(ph)SPGEITSSPQGLDNPALLR ddPTM_HeLa_Curcumin_4h_R1 1 QRQPPGTQQSHSSPGEITSSPQGLDNPALLR 31 1 Q5TDH0-2;Q5TDH0;Q5TDH0-3 Q5TDH0-2 DDI2 Protein DDI1 homolog 2 1 0 QRQPPGTQQS(0.002)HS(0.411)S(0.411)PGEIT(0.074)S(0.074)S(0.028)PQGLDNPALLR 65.795 9.64E-05 7954800 636.94 484.98 567.39 560.76 654.02 553.83 409.35 583.94 770.82 489.5 TRUE FALSE FALSE 586.5255269 526.8995102 588.4179725 558.4397237 646.2212387 438.959415 420.8352593 761.9806179 686.2629745 506.5100886 1.157974027 1.04025472 1.161710272 1.102524385 1.275830933 0.866635088 0.83085267 1.50437402 1.354885105 1 8.984447194 -9.503152519 1.223875988 0.999410591 1.109358687 0 0.212704421 1.322272554 3.513943722 0.122867916 0.029091715 3.14E-10 9.503152519 0.109948096 QRS(ph)DDESPSTSSGSSDADQRDPAAPEPEEQEER ddPTM_HeLa_Curcumin_4h_R1 2 QRSDDESPSTSSGSSDADQRDPAAPEPEEQEER 33 2 R4GMM6;R4GN77;R4GNG6;R4GND1;A0A1B0GX65;Q969T4 R4GMM6 UBE2E3 Ubiquitin-conjugating enzyme E2 E3 1 0 QRS(0.889)DDES(0.107)PS(0.003)T(0.001)SSGSSDADQRDPAAPEPEEQEER;QRS(0.946)DDES(0.053)PS(0.001)TSSGSSDADQRDPAAPEPEEQEER ; 79.365 5.50E-08 51370000 840.03 604.87 917.87 952.55 737.33 1131.88 1074.59 744.22 992.93 728.4 TRUE FALSE FALSE 773.5407391 657.1522676 951.8870696 948.6086005 728.5378213 897.1153291 1104.740103 971.129252 884.0080632 753.7118458 1.026308321 0.871887939 1.262932346 1.258582581 0.966599935 1.190263008 1.465732706 1.288462239 1.172872721 1 9.557869257 -4.609123591 0.419451616 0.999448585 1.587171607 0.345881447 0.13875336 2.460876072 0.355922537 0.033727072 0.684286011 2.46E-05 4.609123591 0.587723021 QRS(ph)IQEDTK ddPTM_HeLa_Curcumin_4h_R1 1 QRSIQEDTK 9 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1;H7BZ98 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 0 QRS(1)IQEDTK 73.082 0.018128 11174000 2866.4 2579.9 2644.6 2478.5 2964.9 4102.4 3913.8 4221.8 2434.4 2791.6 TRUE FALSE FALSE 2639.521415 2802.89506 2742.611202 2468.244624 2929.545504 3251.515996 4023.610695 5509.007385 2167.352411 2888.607892 0.913769371 0.970327287 0.949457768 0.854475483 1.01417209 1.125634256 1.392923804 1.9071496 0.750310354 1 11.49615867 -4.237870933 1.164012079 0.951450751 2.404485995 0.943139613 0.075802935 0.172662189 0.182477689 0.007254991 0.308115322 5.78E-05 4.237870933 1.453035244 QRS(ph)MVWPGDGLVPDTAEPHVAPSPTLPSTEDVIR ddPTM_HeLa_Curcumin_4h_R1 2 QRSMVWPGDGLVPDTAEPHVAPSPTLPSTEDVIR 34 1 F8VXI9;Q14161-6;Q14161-4;Q14161-3;Q14161;R4GNG3;F8WAK2;Q14161-11;Q14161-7;Q14161-10;Q14161-8;Q14161-5;Q14161-9 F8VXI9 GIT2 ARF GTPase-activating protein GIT2 1 0 QRS(0.998)MVWPGDGLVPDT(0.002)AEPHVAPSPTLPSTEDVIR;QRS(0.987)MVWPGDGLVPDT(0.013)AEPHVAPSPTLPSTEDVIR ; 55.846 0.00033889 6242200 537.86 417.44 429.48 530.31 545.1 602.47 700.98 338.21 573 517.74 TRUE FALSE FALSE 495.2878135 453.5216535 445.3969066 528.1157177 538.6000385 477.5109308 720.6476122 441.3286721 510.1433336 535.7314265 0.924507671 0.846546667 0.831380958 0.985784465 1.005354571 0.891325219 1.345165836 0.823787163 0.952237088 1 9.065366118 QRS(ph)PAPGS(ph)PDEEGGAEAPAAGIR ddPTM_HeLa_Curcumin_4h_R1 1 QRSPAPGSPDEEGGAEAPAAGIR 23 1 O15061;H0YL34;A0A075B7B1;O15061-2 O15061 SYNM Synemin 2 0 QRS(1)PAPGS(1)PDEEGGAEAPAAGIR 57.188 0.0076102 38619000 1834.3 1745.6 1802.3 1919 1492.6 1741 1289.5 990.57 1917.1 2375.4 TRUE FALSE FALSE 1689.113219 1896.481886 1869.094823 1911.059686 1474.80172 1379.896975 1325.679899 1292.590233 1706.798926 2457.944973 0.687205465 0.771572149 0.760429889 0.777503039 0.600014132 0.561402712 0.539344824 0.525882494 0.694400788 1 11.2632369 -13.52287875 0.060933204 2.368298727 0.057816336 0.425269688 0.104397258 85.25623818 0.407462688 17.68339783 3.244864787 3.00E-14 13.52287875 -2.310482392 QRS(ph)PAPGSPDEEGGAEAPAAGIR ddPTM_HeLa_Curcumin_4h_R1 2 QRSPAPGSPDEEGGAEAPAAGIR 23 1 O15061;H0YL34;A0A075B7B1;O15061-2 O15061 SYNM Synemin 1 0 QRS(1)PAPGSPDEEGGAEAPAAGIR;QRS(1)PAPGSPDEEGGAEAPAAGIR ; 167.74 3.06E-09 58301000 2583.8 2148.47 2200.77 2041.67 2030.53 800.29 454.88 1022.13 2591.1 2457.96 TRUE FALSE FALSE 2379.289504 2334.174173 2282.332472 2033.222111 2006.317256 634.3008329 467.6427086 1333.772732 2306.862813 2543.373927 0.935485529 0.91774715 0.897364107 0.799419263 0.788840852 0.249393464 0.183867069 0.524410791 0.90700891 1 11.31252787 -5.424844488 2.426455631 0.948927615 0.300272861 0.866249815 0.102699764 0.067586831 0.773253716 0.014997878 0.038399269 3.76E-06 5.424844488 -0.648654755 QRS(ph)PIALPVK ddPTM_HeLa_Curcumin_4h_R1 2 QRSPIALPVK 10 1 Q8TF01;Q8TF01-2 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 0 QRS(1)PIALPVK;QRS(1)PIALPVK ; 101.72 0.0049992 127709000 14532.9 11524.2 15667.2 13389.9 17065.1 16113.4 15085.6 10836.2 12527.1 12814.1 TRUE FALSE FALSE 13382.60563 12520.3005 16247.84021 13334.49614 16861.60983 12771.2992 15508.86134 14140.1075 11152.90847 13259.38902 1.009292782 0.944259232 1.225383778 1.005664448 1.271673212 0.963189117 1.16965128 1.066422252 0.84113291 1 13.69472668 -6.779757649 24.99999809 1.000001196 1.114369591 0.352382191 0.102727123 208.5625079 284636.4821 0.012573269 0.016541728 1.66E-07 6.779757649 0.114368395 QRS(ph)PIALPVKQEPPQIDAVK ddPTM_HeLa_Curcumin_4h_R1 3 QRSPIALPVKQEPPQIDAVK 20 2 Q8TF01;Q8TF01-2 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 0 QRS(1)PIALPVKQEPPQIDAVK;QRS(1)PIALPVKQEPPQIDAVK;QRS(1)PIALPVKQEPPQIDAVK ;; 82.877 0.0016515 283223000 6931.5 5770.6 5788.8 6081.5 5118.5 7084.7 5802.5 4222.16 7381.3 6187.6 TRUE FALSE FALSE 6382.864461 6269.384951 6003.33802 6056.336364 5057.465231 5615.253359 5965.302533 5509.477148 6571.589857 6402.618639 0.996914672 0.97919075 0.937637919 0.945915524 0.789905743 0.877024492 0.931697305 0.860503719 1.026390955 1 12.64444637 -6.382034983 1.495411205 0.997920541 0.8729973 0.696212214 0.038369253 0.158588702 0.698769614 0.006078804 0.010651693 4.15E-07 6.382034983 -0.124923241 QRS(ph)PS(ph)PAPAPAPAAAAGPPTR ddPTM_HeLa_Curcumin_4h_R1 1 QRSPSPAPAPAPAAAAGPPTR 21 1 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 2 0 QRS(1)PS(1)PAPAPAPAAAAGPPTR 65.881 0.0032324 63768000 2124.9 1810.8 1981.7 2114.4 2105.5 2149.8 1794.4 1418.6 2205.7 1412.9 TRUE FALSE FALSE 1956.711923 1967.317483 2055.143545 2105.651173 2080.393288 1703.907247 1844.746035 1851.12461 1963.740228 1461.99817 1.338381924 1.345636078 1.405708699 1.440255683 1.422979406 1.165464692 1.261797773 1.266160689 1.343189252 1 10.51372579 -9.092203722 0.788895043 0.992131383 1.333301108 0 0.131027372 0.320073436 0.350067551 0.066186782 0.018021953 8.09E-10 9.092203722 0.341169725 QRTLS(ph)MIEEEIR ddPTM_HeLa_Curcumin_4h_R1 1 QRTLSMIEEEIR 12 1 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 QRT(0.1)LS(0.9)MIEEEIR 86.777 0.0079607 2327900 2171.9 1401.4 1750.6 1932.4 1666.1 2401.1 1795.7 1342.9 2133.4 1597.3 TRUE FALSE FALSE 1999.991823 1522.530771 1815.478776 1924.404241 1646.232846 1903.084794 1846.082509 1752.344028 1899.371358 1652.806056 1.210058383 0.921179328 1.098422147 1.164325502 0.996023 1.151426562 1.116938374 1.060223625 1.149179815 1 10.69070173 -6.563773235 24.99981678 1.084861753 1.099698245 0.012991311 0.085592633 1276.482157 780342.1323 0.01581501 0.022365803 2.73E-07 6.563773235 0.014836492 QRYDENEDLS(ph)DVEEIVSVR ddPTM_HeLa_Curcumin_4h_R1 2 QRYDENEDLSDVEEIVSVR 19 1 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;S4R3G4;F8WBN2;F6SRV7;F5H0A1 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 0 QRYDENEDLS(1)DVEEIVSVR;QRYDENEDLS(1)DVEEIVSVR ; 134.62 8.06E-05 6316700 2169.37 1540.88 1483.14 1589.14 1768.66 2069.84 1607.66 1233.84 2101.8 1848.36 TRUE FALSE FALSE 1997.662075 1674.066801 1538.106473 1582.56456 1747.569885 1640.531852 1652.766613 1610.032136 1871.237798 1912.590372 1.044479834 0.875287686 0.804200677 0.827445637 0.913718855 0.857753901 0.864150859 0.84180709 0.978378761 1 10.9013122 -7.207600646 5.510642089 1.021013553 0.853582306 0.828323619 0.03174744 0.052798048 3.620797789 0.005308921 0.006481699 6.20E-08 7.207600646 -0.167431247 QRYEILTPNSIPK ddPTM_HeLa_Curcumin_4h_R1 1 QRYEILTPNSIPK 13 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 105.65 0.00064941 0 5076.7 4654.3 4310.4 4313.4 4481.4 4840.5 4640.9 3919.9 4664.3 4829.1 FALSE FALSE TRUE 4674.873838 5056.596953 4470.147216 4295.552294 4427.962232 3836.525736 4771.111164 5115.059465 4152.63796 4996.910866 0.935552777 1.011944597 0.89458214 0.859641568 0.886139927 0.767779502 0.954812141 1.023644328 0.831041031 1 12.28682077 -6.738833545 22.8085787 0.971894581 0.892189541 0.033299549 0.078317221 93.94795483 94789.52193 0.01055105 0.014911837 1.82E-07 6.738833545 -0.07970504 QS(ph)GDGQESTEPVENK ddPTM_HeLa_Curcumin_4h_R1 2 QSGDGQESTEPVENK 15 0 O15234;J3KSY7 O15234 CASC3 Protein CASC3 1 0 QS(1)GDGQESTEPVENK;QS(1)GDGQESTEPVENK ; 220.78 1.45E-14 24632000 2174.2 2032.71 1670.42 1893.48 2899.2 2510.87 1980.8 2480.3 1905.28 1890.81 TRUE FALSE FALSE 2002.109776 2208.408395 1732.327235 1885.645281 2864.628934 1990.087259 2036.375917 3236.532052 1696.275551 1956.515507 1.023303812 1.128745664 0.885414518 0.963777325 1.464148341 1.01715895 1.040817673 1.654232763 0.866988043 1 10.93407083 -2.290012915 1.463197417 1.034844609 199.9938206 0.557908203 0.160893547 244.1215125 2.07127235 0.021477007 161571.8867 0.005128461 2.290012915 198.958976 QS(ph)KS(ph)SGGS(ph)S(ph)S(ph)GTITDEDELTGILK ddPTM_HeLa_Curcumin_4h_R1 1 QSKSSGGSSSGTITDEDELTGILK 24 1 H7C163;A0A0A0MRS7;Q68DC2;Q68DC2-4 H7C163 ANKS6 Ankyrin repeat and SAM domain-containing protein 6 5 0 QS(0.679)KS(0.689)S(0.693)GGS(0.906)S(0.859)S(0.458)GT(0.349)IT(0.365)DEDELT(0.003)GILK 46.982 0.012006 5949300 136.61 212.98 295.07 202.14 315.55 212.28 208.66 277.39 322.34 66.728 TRUE FALSE FALSE 125.7971743 231.3890422 306.0055538 201.3035982 311.7872723 168.2507351 214.514438 361.9649341 286.9801085 69.04679303 1.821911907 3.351191736 4.43185759 2.9154663 4.515593826 2.436763935 3.106797993 5.242313483 4.156313362 1 6.109502503 -7.336273242 2.189087902 1.319890791 3.702238904 0.083055642 1.198775939 0.134953344 1.223478965 0.142399838 0.164222403 4.61E-08 7.336273242 2.382348113 QS(ph)LGESPR ddPTM_HeLa_Curcumin_4h_R1 1 QSLGESPR 8 0 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4;A0A494C1P1;A0A494C1G0;H0Y7N6;F6XFR5 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 QS(0.999)LGES(0.001)PR 98.754 0.015782 8350800 985.43 1020.3 1252.6 1113.7 1540.4 1745.8 967.35 1710 1214.1 1195.4 TRUE FALSE FALSE 907.4321757 1108.490186 1299.022458 1109.091804 1522.031736 1383.701401 994.4912375 2231.371128 1080.916268 1236.940061 0.733610467 0.896155134 1.050190303 0.89664151 1.230481398 1.118648708 0.80399307 1.803944426 0.873863093 1 10.27255988 -4.256664326 24.74579698 0.923090593 1.803944842 0.753323336 0.144477295 179.4253725 929800.2208 0.023239708 0.252732339 5.54E-05 4.256664326 0.880854249 QS(ph)PASPPPLGGGAPVR ddPTM_HeLa_Curcumin_4h_R1 1 QSPASPPPLGGGAPVR 16 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 QS(0.995)PAS(0.005)PPPLGGGAPVR 134.02 0.00043812 8957700 1902.4 1539.1 1312 1722.5 1350.9 2169.7 1216.2 1243.4 2157.7 1479 TRUE FALSE FALSE 1751.823033 1672.132946 1360.623874 1715.372751 1334.7914 1719.679762 1250.323299 1622.506936 1921.005708 1530.39514 1.144686746 1.09261517 0.889067038 1.120869184 0.872187427 1.123683497 0.816993772 1.060188244 1.255235108 1 10.57968848 -6.798161 24.9961049 1.072055194 0.981031749 0.217855836 0.117400066 234.585592 159679.6768 0.016079403 0.021132791 1.59E-07 6.798161 -0.091023446 QS(ph)PGPALAR ddPTM_HeLa_Curcumin_4h_R1 1 QSPGPALAR 9 0 P85037 P85037 FOXK1 Forkhead box protein K1 1 0 QS(1)PGPALAR 114.71 0.007629 199450000 5853.1 4757.9 4456.8 5672.3 5485.5 6749.9 5167.4 2235 4975.1 4324 TRUE FALSE FALSE 5389.820959 5169.151675 4621.972929 5648.829526 5420.088995 5349.894653 5312.383337 2916.441211 4429.343977 4474.258678 1.204628822 1.15530908 1.03301424 1.262517421 1.211393749 1.195705264 1.187321458 0.651826687 0.989961532 1 12.12743295 -4.257034652 24.71812762 1.127950705 0.651826463 0.715302766 0.091782278 180.9021689 1015129.314 0.014172789 0.149757491 5.53E-05 4.257034652 -0.476124243 QS(ph)PLTYEDHGAPFAGHLPR ddPTM_HeLa_Curcumin_4h_R1 1 QSPLTYEDHGAPFAGHLPR 19 0 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 QS(0.993)PLT(0.007)YEDHGAPFAGHLPR 153.25 1.80E-05 11442000 1167.4 929.56 901.25 1095.3 1293.9 1160.2 1283.4 574.24 1258.6 973.44 TRUE FALSE FALSE 1074.999058 1009.907024 934.6511178 1090.767939 1278.471088 919.5614419 1319.40875 749.3231325 1120.534729 1007.266968 1.067243435 1.00262101 0.92790804 1.08289855 1.269247507 0.912927229 1.309889823 0.743917111 1.112450587 1 9.976230393 QS(ph)PNSSSAAASVASR ddPTM_HeLa_Curcumin_4h_R1 2 QSPNSSSAAASVASR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 0 QS(1)PNSSSAAASVASR;QS(0.998)PNS(0.002)S(0.001)SAAASVASR ; 134.08 0.00064645 18857400 2061.95 2157.6 2095.08 2079.51 2046.74 2510 1979.06 1337.15 2327.3 1610.41 TRUE FALSE FALSE 1898.744482 2344.09333 2172.725508 2070.905539 2022.333962 1989.397706 2034.587097 1744.84088 2072.001013 1666.371628 1.139448398 1.406705018 1.30386612 1.242763321 1.213615216 1.193849963 1.220968398 1.047089887 1.243420722 1 10.70249447 -8.029142143 1.340082853 1.033992491 1.230760841 0.01295124 0.111044299 0.245000359 0.910105609 0.022788741 0.019101526 9.35E-09 8.029142143 0.19676835 QS(ph)PPISTSK ddPTM_HeLa_Curcumin_4h_R1 2 QSPPISTSK 9 0 P33981-2;P33981 P33981-2 TTK Dual specificity protein kinase TTK 1 0 QS(0.999)PPIS(0.001)TSK;QS(0.996)PPIS(0.004)TSK ; 91.123 0.018335 24756000 13193.1 10790 12932.9 11806.8 13697.1 13101.2 9996.9 4130.1 10768.3 9663.9 TRUE FALSE FALSE 12148.85221 11722.63952 13412.20465 11757.94659 13533.77103 10383.86344 10277.38611 5389.348477 9587.044431 9999.719806 1.214919263 1.172296799 1.341258046 1.175827605 1.353415025 1.03841544 1.027767408 0.538949949 0.958731306 1 13.28767196 -4.129153332 1.789089142 1.146541698 0.180686046 0.691500947 0.123845079 0.612636084 1.478085471 0.018824693 1.108846712 7.43E-05 4.129153332 -0.965855653 QS(ph)PSPSTRPIR ddPTM_HeLa_Curcumin_4h_R1 2 QSPSPSTRPIR 11 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 QS(0.998)PS(0.002)PSTRPIR;QS(0.995)PS(0.002)PS(0.001)T(0.001)RPIR ; 84.297 0.010248 54501000 5341.9 4882.2 4628.8 5249 5049.8 5845.7 4776.8 4371.1 5868.8 4987.6 TRUE FALSE FALSE 4919.082978 5304.195613 4800.3474 5227.281029 4989.584433 4633.235925 4910.824152 5703.828268 5225.007323 5160.918729 0.95314095 1.027761895 0.930134275 1.012858621 0.96680159 0.897754096 0.951540687 1.105196297 1.012418059 1 12.3334122 IAS(ph)DEEIQGTK ddPTM_HeLa_Curcumin_4h_R1 6 IASDEEIQGTK 11 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;Q8WX93-4;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 0 IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK;IAS(1)DEEIQGTK ;;;;; 219.89 3.30E-11 2719887500 14116.7 11882.1 13098.6 11697.7 14310.9 17861.4 19858.6 42276.4 14049.2 14538.4 TRUE FALSE FALSE 12999.3483 12909.13578 13584.04564 11649.29802 14140.25186 14156.7443 20415.77887 55166.27974 12508.03791 15043.60832 0.864111058 0.858114324 0.902977886 0.774368607 0.939950813 0.941047121 1.357106516 3.667090938 0.831451979 1 13.87686303 -4.238588315 2.669513158 0.916236298 4.307248534 0.993487503 0.067126555 0.031838262 0.281913556 0.011015882 0.24460607 5.77E-05 4.238588315 3.391012236 up QS(ph)SQDNELK ddPTM_HeLa_Curcumin_4h_R1 1 QSSQDNELK 9 0 Q13427;E9PG73 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 0 QS(0.896)S(0.104)QDNELK 103.21 0.011342 5395000 2097.8 2450.5 1621.8 2162.8 1895.8 2738.9 1884.3 1484.6 1783.5 2178.1 TRUE FALSE FALSE 1931.756916 2662.310301 1681.905335 2153.850907 1873.193823 2170.821266 1937.168387 1937.247706 1587.854512 2253.788813 0.857115319 1.181259879 0.746256848 0.955657821 0.831131033 0.963187524 0.859516373 0.859551567 0.704526752 1 11.13813662 QS(ph)VSGLHR ddPTM_HeLa_Curcumin_4h_R1 2 QSVSGLHR 8 0 Q8N1G4;J3KRP5 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 1 0 QS(0.983)VS(0.017)GLHR;QS(0.989)VS(0.011)GLHR ; 89.171 0.010443 4292300 2823.3 2617.8 2397.7 2603.1 2501.4 4594 2447.1 1978.36 3221.1 2286.7 TRUE FALSE FALSE 2599.832826 2844.070967 2486.560871 2592.329062 2471.572439 3641.152615 2515.75904 2581.552857 2867.753389 2366.162655 1.098754906 1.201976103 1.050883322 1.095583626 1.044548833 1.538842906 1.063223204 1.09102933 1.211984892 1 11.20833354 -8.076935355 0.29445278 0.967976543 1.196204 0 0.151843322 2.532618409 0.603573879 0.227689558 0.121924728 8.38E-09 8.076935355 0.228227457 QSACNLEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 QSACNLEKK 9 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 1 QSACNLEK(1)K 142.98 4.42E-06 19550000 4755.4 3316.8 4046.3 3570.5 4030.1 4387.9 3402.4 2912.4 4251 4030.2 FALSE TRUE FALSE 4379.005072 3603.489413 4196.259437 3555.726217 3982.04369 3477.800078 3497.862187 3800.377353 3784.675935 4170.24915 1.050058381 0.864094514 1.006237106 0.852641195 0.954869493 0.833954988 0.838765757 0.911307027 0.907541924 1 12.02591786 -6.723153868 0.942669446 1.022885411 0.873114524 0.168871398 0.06688531 0.274585743 0.487285867 0.010888601 0.017566159 1.89E-07 6.723153868 -0.149770887 QSAEEQAQAR ddPTM_HeLa_Curcumin_4h_R1 1 QSAEEQAQAR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 141.91 2.03E-05 929770 289.59 271.57 237.02 173.07 353.83 372.13 163.81 228.18 328.82 245.71 FALSE FALSE TRUE 266.6686459 295.0433007 245.8041697 172.3538822 349.6108083 294.9460432 168.4060677 297.7510316 292.7492687 254.2484042 1.048850815 1.160452911 0.966787463 0.67789563 1.375075723 1.160070381 0.662368239 1.171102853 1.151430113 1 7.990094909 QSAGPNS(ph)PTGGGGGGGSGGTR ddPTM_HeLa_Curcumin_4h_R1 1 QSAGPNSPTGGGGGGGSGGTR 21 0 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 0 QSAGPNS(0.936)PT(0.064)GGGGGGGSGGTR 200.14 4.95E-14 9375900 2479.6 2325.4 2453.4 2224 2331.1 2797.2 1490.4 1347.5 2879.5 2577.3 TRUE FALSE FALSE 2283.337044 2526.397214 2544.325162 2214.797677 2303.303155 2217.029189 1532.216613 1758.346547 2563.626054 2666.860983 0.856189002 0.947329925 0.954052415 0.830488612 0.863675748 0.831325368 0.574539364 0.65933191 0.961289722 1 11.38092691 -4.946511168 0.9782008 0.931196384 0.567137008 0.796290404 0.058557278 0.317875247 0.426103755 0.010786599 0.094418131 1.13E-05 4.946511168 -0.364059376 QSAGPNSPT(ph)GGGGGGGSGGTR ddPTM_HeLa_Curcumin_4h_R1 1 QSAGPNSPTGGGGGGGSGGTR 21 0 H7BZ52;S4R3H3;S4R393;S4R410;A7E2V4-5;A7E2V4;A7E2V4-3;A7E2V4-4;A7E2V4-2 H7BZ52 ZSWIM8 Zinc finger SWIM domain-containing protein 8 1 0 QSAGPNS(0.235)PT(0.765)GGGGGGGSGGTR 207.1 4.55E-17 7268000 1585.6 1367.5 1472.1 1499.3 1353.7 1840.3 883.99 853.96 1520.7 1414.9 TRUE FALSE FALSE 1460.098087 1485.700607 1526.657321 1493.096294 1337.558012 1458.601036 908.7923803 1114.328473 1353.883015 1464.06767 0.997288662 1.014775913 1.042750518 1.019827379 0.913590293 0.996266133 0.620731131 0.761118148 0.924740736 1 10.51576652 -4.769757682 24.99874244 0.998281641 0.69092463 0.848675418 0.05015669 32.35363709 97232.61916 0.005708426 0.017545408 1.70E-05 4.769757682 -0.307357011 QSELSAEES(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 2 QSELSAEESPEK 12 0 F8W9X7;Q567U6 F8W9X7 CCDC93 Coiled-coil domain-containing protein 93 1 0 QSELSAEES(1)PEK;QS(0.001)ELS(0.008)AEES(0.992)PEK ; 142.95 0.0010175 47098000 5043.2 4113.2 5244.7 5544.6 5706.3 5454.7 4800.4 4293.1 5173.1 4330.3 TRUE FALSE FALSE 4644.025398 4468.72668 5439.073196 5521.657914 5638.256099 4323.333733 4935.086304 5602.046427 4605.623872 4480.777603 1.036432916 0.997310529 1.213868145 1.232299035 1.258320899 0.964862378 1.101390594 1.250239785 1.027862635 1 12.12953341 -6.768673684 24.99922959 1.016193093 1.164537067 0.456577679 0.08257583 121.7684412 420788.8097 0.013655887 0.01815494 1.70E-07 6.768673684 0.148343974 QSETVDQNS(ph)DS(ph)DEMLAILK ddPTM_HeLa_Curcumin_4h_R1 1 QSETVDQNSDSDEMLAILK 19 0 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6;A0A096LNW1 P46100-5 ATRX Transcriptional regulator ATRX 2 0 QS(0.002)ET(0.001)VDQNS(0.999)DS(0.999)DEMLAILK 64.954 0.013782 3954000 1411.7 1196.8 1136.1 1202.1 1175.8 1500.1 1140.4 873.49 1196.3 1230.1 TRUE FALSE FALSE 1299.962455 1300.246059 1178.204865 1197.126029 1161.779353 1188.96235 1172.396555 1139.81308 1065.068883 1272.845883 1.021303893 1.021526703 0.925646129 0.940511372 0.912741572 0.934097651 0.921082882 0.895483966 0.836761855 1 10.31384203 -6.756150553 24.98203864 1.011201256 0.922596541 0 0.05662179 26.48817867 125117.7279 0.002216811 0.003082581 1.75E-07 6.756150553 -0.088604715 QSETVDQNS(ph)DSDEMLAILK ddPTM_HeLa_Curcumin_4h_R1 1 QSETVDQNSDSDEMLAILK 19 0 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6;A0A096LNW1 P46100-5 ATRX Transcriptional regulator ATRX 1 0 QSETVDQNS(1)DSDEMLAILK 148.33 5.59E-05 5114100 3618.3 2477.3 3102.3 2965.8 2684.6 3644 2608.3 1827.2 2773 2521.9 TRUE FALSE FALSE 3331.907737 2691.426773 3217.273967 2953.528305 2652.587898 2888.193324 2681.481878 2384.304869 2468.808838 2609.535837 1.276820073 1.031381418 1.232891276 1.131821324 1.016497977 1.106784311 1.027570436 0.91368926 0.946072019 1 11.3495775 -3.680269068 0.74664079 1.130585859 0.545672894 0.178645816 0.101447876 5.866238465 1.269585353 0.018162046 3.523857405 0.0002088 3.680269068 -0.584912964 QSFDDNDS(ph)EELEDK ddPTM_HeLa_Curcumin_4h_R1 1 QSFDDNDSEELEDK 14 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 0 QSFDDNDS(1)EELEDK 103.66 0.0039356 2979200 1302.2 1075.5 1338.6 1081.7 1396.7 1493.9 1010.2 1169.6 1204.1 1328.2 TRUE FALSE FALSE 1199.129496 1168.461428 1388.209694 1077.224212 1380.045265 1184.0483 1038.543493 1526.205656 1072.013243 1374.354851 0.872503557 0.850189037 1.010080979 0.783803551 1.004140425 0.861530266 0.755658913 1.11048879 0.780011976 1 10.42453883 -9.354783066 1.040120187 1.000921133 0.898550963 0 0.123621293 0.872030865 1.664684808 0.066308826 0.016675339 4.42E-10 9.354783066 -0.10237017 QSFDDNDS(ph)EELEDKDSK ddPTM_HeLa_Curcumin_4h_R1 4 QSFDDNDSEELEDKDSK 17 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 0 QSFDDNDS(0.997)EELEDKDS(0.003)K;QSFDDNDS(1)EELEDKDSK;QSFDDNDS(0.996)EELEDKDS(0.003)K;QSFDDNDS(0.903)EELEDKDS(0.097)K ;;; 145.73 0.00012142 3942230000 13698.3 10248.4 12447.9 12720.1 10607.5 11503.9 9681 8413.3 12492.1 10845 TRUE FALSE FALSE 12614.0651 11134.22603 12909.23012 12667.4676 10481.01249 9117.861464 9952.622805 10978.47644 11121.74788 11221.86294 1.12406159 0.99219052 1.150364266 1.12882038 0.933981509 0.812508717 0.886895773 0.978311399 0.991078571 1 13.45402458 -5.619714424 5.612022241 1.06616095 0.889163657 0.591797912 0.066246371 0.110289409 5.268890612 0.010184055 0.020614267 2.40E-06 5.619714424 -0.176997293 QSFTMVADT(ph)PENLR ddPTM_HeLa_Curcumin_4h_R1 1 QSFTMVADTPENLR 14 0 C9J9W2;Q14847;Q14847-2;F6S2S5 C9J9W2 LASP1 LIM and SH3 domain protein 1 1 0 QSFTMVADT(1)PENLR 276.14 1.64E-62 107740000 2704.5 1969.6 2021.4 2372.4 2672.2 5110 4294.7 1221.7 2083.7 1484.1 TRUE FALSE FALSE 2490.435971 2139.843448 2096.314862 2362.583637 2640.33576 4050.128398 4415.197723 1594.190706 1855.123323 1535.672365 1.621723506 1.393424468 1.365079499 1.538468551 1.719335336 2.637364904 2.875090954 1.038106007 1.208020256 1 10.58465473 -5.597551392 2.66950294 1.325408897 2.246812022 0.369330939 0.478600146 0.201480346 2.895621829 0.071047319 0.159962187 2.53E-06 5.597551392 0.921403126 QSGLSSLVNGK(ac)SPIR ddPTM_HeLa_Curcumin_4h_R1 2 QSGLSSLVNGKSPIR 15 1 H0Y612;Q9UPN9-2;Q9UPN9 H0Y612 TRIM33 E3 ubiquitin-protein ligase TRIM33 0 1 ; QSGLSSLVNGK(1)SPIR;QSGLSSLVNGK(1)SPIR 228.93 1.81E-36 4193100 229.53 142.09 303.509 246.67 251.03 271.15 359.79 400.99 120.79 142.69 FALSE TRUE FALSE 211.3624583 154.3716265 314.7573105 245.6493449 248.0366312 214.9104335 369.8847391 523.2500051 107.5396392 147.6484669 1.43152491 1.04553491 2.131802092 1.663744637 1.679913354 1.455554792 2.505171553 3.54389054 0.728349176 1 7.206022566 -1 0.468802374 1.226331749 59.54863423 0.790669996 0.361046437 25.81561562 0.267386095 0.071516472 1468.9643 0.1 1 58.32230248 QSGLSSLVNGKS(ph)PIR ddPTM_HeLa_Curcumin_4h_R1 1 QSGLSSLVNGKSPIR 15 1 H0Y612;Q9UPN9-2;Q9UPN9 H0Y612 TRIM33 E3 ubiquitin-protein ligase TRIM33 1 0 QSGLS(0.003)S(0.002)LVNGKS(0.995)PIR 127.49 0.007349 33786000 1383.2 1204.6 1275 1275.5 1002.7 938.29 1058.9 864.63 1371.8 1059.5 TRUE FALSE FALSE 1273.71826 1308.720256 1322.252622 1270.222319 990.7434574 743.6780773 1088.609884 1128.251707 1221.316972 1096.317546 1.161815083 1.19374196 1.206085432 1.158626279 0.903701178 0.678341854 0.992969499 1.029128568 1.114017537 1 10.09845002 -5.749185219 23.06535115 1.103913741 0.891695115 0.53694377 0.105148735 67.36796812 126800.5041 0.017545349 0.034840805 1.78E-06 5.749185219 -0.212218626 QSHAASAAPQASSPPDYT(ph)MAWAEYYR ddPTM_HeLa_Curcumin_4h_R1 1 QSHAASAAPQASSPPDYTMAWAEYYR 26 0 Q96I24 Q96I24 FUBP3 Far upstream element-binding protein 3 1 0 QSHAASAAPQAS(0.012)S(0.004)PPDY(0.263)T(0.299)MAWAEY(0.211)Y(0.211)R 52.927 0.01267 16359000 1571.8 1138.2 991.18 1082.4 1294.9 2493.6 1478.6 931.18 1483.2 1191 TRUE FALSE FALSE 1447.390371 1236.580936 1027.914003 1077.921316 1279.459163 1976.399251 1520.085537 1215.092495 1320.496671 1232.387161 1.174460768 1.003402969 0.834083667 0.874661267 1.038195791 1.603716197 1.233448046 0.985966532 1.071494991 1 10.26723984 QSHS(ph)ES(ph)PSLQSK ddPTM_HeLa_Curcumin_4h_R1 1 QSHSESPSLQSK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 QS(0.137)HS(0.876)ES(0.981)PS(0.006)LQSK 78.69 0.0086282 0 5995.8 4670.5 5708.2 5948.9 5542.9 7090.1 4639.9 4027 6986.7 5582.8 TRUE FALSE FALSE 5521.226103 5074.197209 5919.750913 5924.285028 5476.804538 5619.533338 4770.083106 5254.813762 6220.27649 5776.801884 0.955758258 0.878374802 1.024745358 1.025530241 0.948068611 0.972775846 0.825730777 0.90964064 1.076768187 1 12.4960553 -4.777098044 24.46324746 0.975515233 0.867685735 0.416785908 0.054666836 100.001292 156231.2262 0.006219475 0.01875755 1.67E-05 4.777098044 -0.107829498 QSHSES(ph)PSLQSK ddPTM_HeLa_Curcumin_4h_R1 5 QSHSESPSLQSK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 QSHS(0.002)ES(0.991)PS(0.007)LQSK;QS(0.001)HS(0.004)ES(0.909)PS(0.086)LQSK;QS(0.207)HS(0.061)ES(0.652)PS(0.08)LQSK;QS(0.019)HS(0.41)ES(0.53)PS(0.042)LQSK;QS(0.027)HS(0.1)ES(0.856)PS(0.018)LQSK ;;;; 266.07 3.72E-46 1101609200 23473.06 19585.74 18990.18 19955.77 22335.51 26447.42 20570.38 16694.94 23411.25 18821.43 TRUE FALSE FALSE 21615.14253 21278.64409 19693.97278 19873.19831 22069.17363 20961.92697 21147.5295 21785.15035 20843.09445 19475.47329 1.109864813 1.092586751 1.011219213 1.020421841 1.133177782 1.076324393 1.085854458 1.118594143 1.070222743 1 14.24937077 -9.435983152 1.112848035 0.999032528 1.081602414 0.070680234 0.042595175 0.438297838 0.952695581 0.028597598 0.006825509 3.66E-10 9.435983152 0.082569885 QSHSGSIS(ph)PYPK ddPTM_HeLa_Curcumin_4h_R1 4 QSHSGSISPYPK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 QSHSGSIS(1)PYPK;QSHSGSIS(1)PYPK;QSHSGS(0.002)IS(0.997)PYPK;QSHSGSIS(1)PYPK ;;; 219.84 1.85E-13 367684000 24075.4 21733.2 20914.3 20171.4 30589.5 31040.9 21784.2 15778.8 23869.6 18570.5 TRUE FALSE FALSE 22169.80669 23611.72097 21689.40236 20087.93609 30224.74019 24602.66744 22395.40602 20589.68348 21251.1646 19215.82349 1.153726599 1.228764459 1.128726144 1.045385127 1.572908921 1.280333754 1.165466889 1.071496285 1.105920056 1 14.23000718 -8.369881618 0.461430204 0.987291434 1.234962422 0.154843007 0.141800018 1.137909839 0.521809493 0.122920192 0.050630418 4.27E-09 8.369881618 0.247670988 APS(ph)DSSLGTPS(ph)DGRPELR ddPTM_HeLa_Curcumin_4h_R1 1 APSDSSLGTPSDGRPELR 18 1 M0R0F9;W4VSQ9;Q15642-4;Q15642-2;Q15642-3;Q15642;M0R2H7;Q15642-5 M0R0F9 TRIP10 Cdc42-interacting protein 4 2 0 APS(0.659)DS(0.282)S(0.211)LGT(0.14)PS(0.708)DGRPELR 68.676 0.011289 64137000 3437.3 3361.8 3056.4 3062.8 2805 3989.9 2313.7 495.93 3593.6 2874.5 TRUE FALSE FALSE 3165.234078 3652.379012 3169.672873 3050.126945 2771.552207 3162.349765 2378.616195 647.136774 3199.391071 2974.388661 1.064162905 1.227942757 1.065655243 1.025463479 0.931805666 1.063193189 0.799699187 0.217569675 1.075646607 1 11.53837746 -4.274893092 2.061657642 1.043061989 9.20E-18 0.924395509 0.072735211 0.135458327 0.634028638 0.010807344 0.26035979 5.31E-05 4.274893092 -1.043061989 down QSLS(ph)PMSQRPVLK ddPTM_HeLa_Curcumin_4h_R1 2 QSLSPMSQRPVLK 13 1 Q9NSV4-1;Q9NSV4-7;Q9NSV4-6;Q9NSV4-5;Q9NSV4-4;Q9NSV4 Q9NSV4-1 DIAPH3 Protein diaphanous homolog 3 1 0 QS(0.006)LS(0.993)PMS(0.001)QRPVLK;QS(0.406)LS(0.59)PMS(0.004)QRPVLK ; 167.03 0.0017586 147164000 5647.5 4714.7 5089.9 5446.5 4574.4 5359.5 3447.2 1605.39 6131.9 4642.5 TRUE FALSE FALSE 5200.494416 5122.21766 5278.536172 5423.963826 4519.853268 4247.879286 3543.919154 2094.866021 5459.245911 4803.826529 1.082573316 1.066278649 1.098819064 1.129092359 0.940886029 0.884269917 0.737728378 0.436082779 1.136436938 1 12.22996834 -4.274187001 0.967605489 1.051414903 0.118615388 0.936632299 0.052570794 0.344763208 0.247125431 0.008316443 0.333577927 5.32E-05 4.274187001 -0.932799516 down QSMAFSILNT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 QSMAFSILNTPK 12 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 QSMAFS(0.027)ILNT(0.973)PK;QSMAFSILNT(1)PK ; 184.01 0.00016447 287800000 7476.4 4675.2 6423.8 5821 5940.8 9415.9 7998.2 1588.87 7531.6 6065.2 TRUE FALSE FALSE 6884.635051 5079.303456 6661.871679 5796.914244 5869.95984 7462.936201 8222.607966 2073.309149 6705.402323 6275.965249 1.096984253 0.809326256 1.061489574 0.923668952 0.935307894 1.189129625 1.310174235 0.330357015 1.068425662 1 12.61562165 -4.247447137 24.99989195 1.039198806 0.330356543 0.718843222 0.133834089 1005.641528 1796747.372 0.018187158 0.508801712 5.66E-05 4.247447137 -0.708842263 QSMAFSILNT(ph)PKK ddPTM_HeLa_Curcumin_4h_R1 1 QSMAFSILNTPKK 13 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 QSMAFS(0.002)ILNT(0.998)PKK 77.13 0.01333 36784000 2489.4 2117.8 1936.8 2338.1 1740.1 3084.9 2545.7 506.37 2234.5 1993.6 TRUE FALSE FALSE 2292.361363 2300.853195 2008.579512 2328.425562 1719.350444 2445.056966 2617.125491 660.759882 1989.38094 2062.877452 1.111244568 1.115361067 0.973678543 1.128727041 0.833471927 1.185265254 1.268677152 0.320309809 0.964371848 1 11.0104424 -4.251528327 24.99048102 1.06257415 0.320309408 0.779481607 0.118748706 450.85478 1136796.905 0.015259208 0.275515677 5.60E-05 4.251528327 -0.742264743 QSNAS(ph)SDVEVEEK ddPTM_HeLa_Curcumin_4h_R1 2 QSNASSDVEVEEK 13 0 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 1 0 QS(0.166)NAS(0.417)S(0.417)DVEVEEK;QSNAS(0.5)S(0.5)DVEVEEK ; 300.56 1.77E-87 441112900 9953.7 8545.2 8935.4 9414.2 11386 10785.6 9296.9 7845.4 8203.3 7455.7 TRUE FALSE FALSE 9165.854142 9283.809011 9266.553784 9375.246535 11250.22939 8548.544981 9557.745993 10237.42634 7303.418514 7714.78502 1.188089379 1.203378835 1.201142191 1.21523108 1.458268682 1.108073 1.238886886 1.326987896 0.946678163 1 12.91341024 -8.875667759 0.328856197 0.924264883 1.280372604 0.621328828 0.086165504 1.401498247 0.251251119 0.190015074 0.045310662 1.33E-09 8.875667759 0.356107721 QSNASS(ph)DVEVEEK ddPTM_HeLa_Curcumin_4h_R1 2 QSNASSDVEVEEK 13 0 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 1 0 QSNAS(0.027)S(0.973)DVEVEEK;QSNAS(0.065)S(0.935)DVEVEEK ; 178.22 0.0001835 28671000 8135.8 6056.2 6388.4 7087.6 7171.9 9890.9 8921.9 5009.9 8177.7 7456.1 TRUE FALSE FALSE 7491.842845 6579.670942 6625.159724 7058.273389 7086.379777 7839.415847 9172.224502 6537.395447 7280.62677 7715.19892 0.971049862 0.852819352 0.858715348 0.914853066 0.918496056 1.016100288 1.188851331 0.847339844 0.943673241 1 12.91348764 QSNASSDVEVEEKET(ph)SVSKEDTDHEEK ddPTM_HeLa_Curcumin_4h_R1 2 QSNASSDVEVEEKETSVSKEDTDHEEK 27 2 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 1 0 QSNAS(0.002)S(0.004)DVEVEEKET(0.461)S(0.461)VS(0.043)KEDT(0.029)DHEEK;QSNASS(0.001)DVEVEEKET(0.475)S(0.475)VS(0.043)KEDT(0.006)DHEEK ; 64.246 0.00064288 26808700 3615.4 2591.2 3101 3436.6 3425.2 4005.7 3135.2 2447.7 3422.8 2838.5 TRUE FALSE FALSE 3329.237275 2815.171782 3215.925788 3422.38026 3384.356727 3174.872666 3223.165274 3193.992462 3047.327403 2937.137664 1.133497185 0.958474578 1.094918304 1.165209347 1.152263569 1.080941049 1.097383113 1.087450718 1.037516028 1 11.52019517 -9.511202348 0.936321518 0.991786469 1.099550855 0.232360524 0.054640597 0.701524302 0.95421891 0.057171099 0.01012779 3.08E-10 9.511202348 0.107764386 QSNPKSS(ph)PGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR ddPTM_HeLa_Curcumin_4h_R1 1 QSNPKSSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR 41 2 P40222 P40222 TXLNA Alpha-taxilin 1 0 QS(0.042)NPKS(0.234)S(0.722)PGQPEAGPEGAQERPS(0.002)QAAPAVEAEGPGSSQAPR 58.184 4.78E-05 8432900 1362.5 1047.5 1227 1107.9 875.7 1664 1370.7 864.74 1875.6 1542.9 TRUE FALSE FALSE 1254.656687 1138.041232 1272.473699 1103.315803 865.2578494 1318.867643 1409.158153 1128.395245 1669.851373 1596.51566 0.785871832 0.712828105 0.797031768 0.691077345 0.541966403 0.826091266 0.882645995 0.706786205 1.045934853 1 10.64071099 -8.746399184 0.621836778 1.007154689 0.736187052 0.608701079 0.089109587 0.491156563 0.358750079 0.067533886 0.022181739 1.79E-09 8.746399184 -0.270967637 QSNVAAPGDAT(ph)PPAEK ddPTM_HeLa_Curcumin_4h_R1 1 QSNVAAPGDATPPAEK 16 0 Q96QC0 Q96QC0 PPP1R10 Serine/threonine-protein phosphatase 1 regulatory subunit 10 1 0 QS(0.04)NVAAPGDAT(0.96)PPAEK 113.86 0.0088408 0 4318.2 3442 3161.3 3551.9 3758.4 5537.9 5018.1 3396.8 3184.3 2981.1 TRUE FALSE FALSE 3976.409913 3739.511143 3278.460559 3537.203179 3713.583535 4389.277115 5158.89438 4432.468683 2834.990257 3084.693003 1.289078009 1.212279841 1.062815831 1.146695368 1.203874593 1.422921863 1.672417442 1.436923765 0.919051022 1 11.5909112 -1 0.233853602 1.073448325 4.081803245 0.637467876 0.129739519 26.68854918 0.326476869 0.089865389 31.23052948 0.1 1 3.00835492 QSPAS(ph)PPPLGGGAPVR ddPTM_HeLa_Curcumin_4h_R1 1 QSPASPPPLGGGAPVR 16 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 QS(0.026)PAS(0.974)PPPLGGGAPVR 188.16 1.10E-06 14777000 2349.9 1982.1 1728.2 2358.6 1624.2 2525 1399.5 1589.3 2800.2 1677.5 TRUE FALSE FALSE 2163.902935 2153.423892 1792.248612 2348.840738 1604.832476 2001.286537 1438.766203 2073.870254 2493.025066 1735.793 1.246636514 1.240599479 1.032524392 1.353180211 0.924552914 1.152952303 0.828881211 1.194768186 1.436245604 1 10.7613792 QSPGSTS(ph)PKPPHTLSR ddPTM_HeLa_Curcumin_4h_R1 1 QSPGSTSPKPPHTLSR 16 1 E9PPY3;O43159 E9PPY3 RRP8 Ribosomal RNA-processing protein 8 1 0 QS(0.032)PGS(0.055)T(0.055)S(0.857)PKPPHTLSR 62.002 0.014321 9912300 1330.6 1081.8 1278.1 1292 1527.1 1685 905.18 554.53 1442.8 1172.9 TRUE FALSE FALSE 1225.281606 1175.305972 1325.46751 1286.654046 1508.89033 1335.512006 930.5769146 723.6036443 1284.52845 1213.658188 1.009577176 0.968399491 1.092125875 1.060145319 1.243258065 1.10040209 0.766753707 0.596217 1.058393922 1 10.24514645 -4.594333676 3.870462472 1.034102229 0.625824373 0.796708942 0.078381189 0.077632078 2.219644837 0.01218405 0.056090232 2.54E-05 4.594333676 -0.408277856 GLVAAYSGES(ph)DS(ph)EEEQER ddPTM_HeLa_Curcumin_4h_R1 5 GLVAAYSGESDSEEEQER 18 0 P98175-5;P98175-2;P98175;P98175-4;P98175-3 P98175-5 RBM10 RNA-binding protein 10 2 0 GLVAAY(0.025)S(0.282)GES(0.945)DS(0.749)EEEQER;GLVAAY(0.002)S(0.017)GES(0.982)DS(0.999)EEEQER;GLVAAY(0.039)S(0.276)GES(0.971)DS(0.715)EEEQER;GLVAAY(0.323)S(0.258)GES(0.837)DS(0.581)EEEQER;GLVAAY(0.064)S(0.438)GES(0.95)DS(0.548)EEEQER ;;;; 115.58 0.0010242 75378600 12756.52 12102.4 12288.03 11367.31 14199.07 14535.19 15028.94 17459.88 11770.74 10953.75 TRUE FALSE FALSE 11746.82798 13148.47753 12743.4352 11320.27508 14029.75536 11520.42775 15450.61161 22783.31704 10479.51927 11334.392 1.036388011 1.16005142 1.124315729 0.998754506 1.237803966 1.016413386 1.363161925 2.010104913 0.924577099 1 13.46841938 -4.238339226 1.781550965 1.04698568 2.376125201 0.911973441 0.089344709 0.171519383 0.512514114 0.011789648 0.390000866 5.78E-05 4.238339226 1.329139521 up QSPSPS(ph)EVSQSPGR ddPTM_HeLa_Curcumin_4h_R1 1 QSPSPSEVSQSPGR 14 0 C9JHC0;A0A5F9ZHX4;A0A5F9ZHW9;A0A5F9ZH11;P55201-4;P55201-3;P55201;P55201-2 C9JHC0 BRPF1 Peregrin 1 0 QS(0.035)PS(0.377)PS(0.548)EVS(0.004)QS(0.037)PGR 130.47 0.00078195 0 613.29 633.33 715.33 583.62 503.31 696.34 675.77 423.23 580.24 716.25 TRUE FALSE FALSE 564.7474494 688.0722231 741.8407591 581.2051351 497.308357 551.9112346 694.7302875 552.2708787 516.5891237 741.1396342 0.761998716 0.928397553 1.000946009 0.784204633 0.671004942 0.744679152 0.937381103 0.745164411 0.697019967 1 9.533601568 -6.113117695 10.76688828 0.896162877 0.777037677 0.166901608 0.109304938 0.582004272 52.01013959 0.017037058 0.028268282 7.71E-07 6.113117695 -0.1191252 QSQESLPGAVS(ph)PLSGR ddPTM_HeLa_Curcumin_4h_R1 2 QSQESLPGAVSPLSGR 16 0 Q69YU3 Q69YU3 ANKRD34A Ankyrin repeat domain-containing protein 34A 1 0 QSQESLPGAVS(0.997)PLS(0.003)GR;QSQESLPGAVS(0.993)PLS(0.007)GR ; 139.11 0.00040169 20881900 3827.1 2766.4 3467.9 3397.7 3555.9 5216 5523.8 1668.71 3846.7 2960 TRUE FALSE FALSE 3524.180997 3005.515289 3596.423425 3383.641218 3513.498215 4134.142804 5678.782961 2177.491997 3424.726634 3062.85978 1.150617805 0.981277468 1.174204398 1.104732655 1.147129959 1.349765612 1.854078662 0.710934275 1.118146726 1 11.58066361 -5.363514087 3.57032462 1.077523589 1.35961973 0.107743602 0.264184214 0.289208266 6.804480125 0.034305467 0.08245346 4.33E-06 5.363514087 0.282096141 QSQIQVFEDGADT(ph)TSPETPDSSASK ddPTM_HeLa_Curcumin_4h_R1 1 QSQIQVFEDGADTTSPETPDSSASK 25 0 C9JJD0;C9JKG6;E9PCY0;Q6AWB1;E7EX90;Q14203-3;Q14203-4;Q14203-6;Q14203 C9JJD0 DCTN1;DKFZp686E0752 Dynactin subunit 1 1 0 QSQIQVFEDGADT(0.31)T(0.31)S(0.31)PET(0.068)PDS(0.003)S(0.001)ASK 81.839 0.00012723 4638400 4499.4 3537.5 3442.9 3801.1 4284.8 4904.4 4305.7 3632.7 4159.3 3095.1 TRUE FALSE FALSE 4143.267742 3843.265737 3570.496903 3785.372055 4233.706558 3887.172156 4426.506354 4740.293507 3703.035196 3202.654495 1.293698009 1.200025087 1.114855477 1.181948306 1.321936714 1.21373447 1.382136712 1.480113923 1.156239364 1 11.64505245 -13.52287874 0.059192487 2.09E-08 1.732489437 0.542576029 0.088978971 171.797163 0.798978432 26.17349035 5.03328173 3.00E-14 13.52287874 1.732489416 QSQQPMKPIS(ph)PVKDPVS(ph)PASQK ddPTM_HeLa_Curcumin_4h_R1 2 QSQQPMKPISPVKDPVSPASQK 22 2 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 QS(0.003)QQPMKPIS(0.784)PVKDPVS(0.9)PAS(0.313)QK;QS(0.411)QQPMKPIS(0.616)PVKDPVS(0.934)PAS(0.038)QK ; 57.39 0.0093462 187392000 6148.9 5465 5346.5 5602 5676.2 6031.9 4993 4375.1 5864.1 5565.3 TRUE FALSE FALSE 5662.208077 5937.370248 5544.645993 5578.820408 5608.515022 4780.815946 5133.090142 5709.04785 5220.822901 5758.693761 0.983245214 1.03102726 0.9628305 0.968764904 0.973921388 0.830191037 0.891363624 0.991378963 0.906598461 1 12.49152589 -5.462276927 10.3592798 0.990465367 0.902741167 0.282732496 0.048276723 0.414442218 69.53410273 0.005510882 0.012317246 3.45E-06 5.462276927 -0.0877242 QSQQPMKPIS(ph)PVKDPVSPASQK ddPTM_HeLa_Curcumin_4h_R1 3 QSQQPMKPISPVKDPVSPASQK 22 2 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 QS(0.002)QQPMKPIS(0.996)PVKDPVS(0.002)PASQK;QSQQPMKPIS(0.993)PVKDPVS(0.007)PASQK;QSQQPMKPIS(0.988)PVKDPVS(0.01)PAS(0.001)QK ;; 93.446 0.00018445 75313000 7470.2 6123.1 6251.27 6393.7 5768.09 7475.3 6809.7 4617.02 7430.8 5556.85 TRUE FALSE FALSE 6878.925787 6652.35348 6482.947565 6367.244564 5699.309294 5924.838516 7000.761855 6024.728144 6615.659831 5749.950124 1.196345297 1.156941075 1.127478922 1.107356486 0.991192823 1.030415636 1.217534362 1.047787896 1.150559516 1 12.48933373 QSS(ph)APASPAASAAGLAGQAAK ddPTM_HeLa_Curcumin_4h_R1 2 QSSAPASPAASAAGLAGQAAK 21 0 Q5SWX3;Q13555-5;Q13555-11;Q13555-6 Q5SWX3 CAMK2G 1 0 QS(0.065)S(0.92)APAS(0.015)PAASAAGLAGQAAK;QS(0.082)S(0.91)APAS(0.008)PAASAAGLAGQAAK ; 151.21 1.67E-10 0 1855.24 1494.49 1460.19 1506.53 1318.19 2643 3202.5 958.5 2168.02 1746.89 TRUE FALSE FALSE 1708.395796 1623.667056 1514.305926 1500.296378 1302.471445 2094.812007 3292.353531 1250.742238 1930.19363 1807.594297 0.945121258 0.898247499 0.837746572 0.829996189 0.720555186 1.158895008 1.821400707 0.691937477 1.067824585 1 10.8198552 -5.006507342 24.99999643 0.931801091 1.315038741 0.225253999 0.270730438 267.3308218 1027051.006 0.03313776 0.094598327 9.85E-06 5.006507342 0.38323765 QSS(ph)FEIPDDVPLPAGWEMAK ddPTM_HeLa_Curcumin_4h_R1 1 QSSFEIPDDVPLPAGWEMAK 20 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8 P46937-6 YAP1 Transcriptional coactivator YAP1 1 0 QS(0.167)S(0.833)FEIPDDVPLPAGWEMAK 130.72 5.16E-05 6351500 2752.1 2153.4 2493.5 2779.6 2181 4308.7 3154.3 3053.2 3299.8 2506.1 TRUE FALSE FALSE 2534.268381 2339.530301 2585.911304 2768.098752 2154.992999 3415.027051 3242.801169 3984.106625 2937.820196 2593.186788 0.977279536 0.902183488 0.997194385 1.067450584 0.831021124 1.316922894 1.250508133 1.53637472 1.132899569 1 11.34051041 -4.862686309 1.533357171 0.979925505 1.480580715 0.720904561 0.106889243 0.146361732 0.590645068 0.012440469 0.078432926 1.37E-05 4.862686309 0.50065521 S(ph)EDDSAVPLAK ddPTM_HeLa_Curcumin_4h_R1 1 SEDDSAVPLAK 11 0 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 0 S(1)EDDSAVPLAK 138.75 0.0015342 9078900 904.12 909.64 906.82 1020.6 971.63 1170.7 1627.9 4144.6 855.78 881.86 TRUE FALSE FALSE 832.557948 988.2652283 940.4275469 1016.377028 960.0439468 927.8836235 1673.574493 5408.269461 761.9030751 912.5045694 0.912387703 1.083024964 1.03060037 1.113832261 1.052097687 1.016853674 1.834045055 5.926840963 0.834958093 1 9.833687973 -4.237974965 2.592007208 0.993130594 7.12879171 0.996685013 0.084733903 0.021607121 0.175685797 0.012797505 0.294758754 5.78E-05 4.237974965 6.135661116 up QSS(ph)GASSSSFSSSR ddPTM_HeLa_Curcumin_4h_R1 3 QSSGASSSSFSSSR 14 0 A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8Y5G6;A0A2R8YFR4;A0A0D9SFB3;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;A0A0D9SF53;A0A2R8YF78;F6S8Q4;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;A0A0J9YVQ7;A0A087WVZ1 A0A2R8YCW1 DDX3X ATP-dependent RNA helicase DDX3X 1 0 QS(0.002)S(0.969)GAS(0.013)S(0.007)S(0.007)SFSS(0.001)SR;QS(0.002)S(0.989)GAS(0.001)S(0.002)S(0.005)SFSSSR;QS(0.009)S(0.991)GASSSSFSSSR ;; 213 1.04E-13 34696400 6816.02 4924.54 6120.77 6077.2 6118.7 11452.1 11330.8 5318.79 5294.1 5348.2 TRUE FALSE FALSE 6276.524825 5350.195294 6347.611121 6052.054157 6045.738499 9076.805368 11648.71175 6940.464586 4713.350475 5534.049552 1.134164912 0.966777627 1.147010171 1.093603174 1.092461938 1.640174213 2.104916417 1.254138497 0.851700085 1 12.43411985 -5.24255454 4.62736008 1.066480264 1.721005645 0.649595551 0.209551111 0.076020918 4.351928195 0.025166818 0.063875894 5.72E-06 5.24255454 0.654525381 KHS(ph)PSPPPPTPTESR ddPTM_HeLa_Curcumin_4h_R1 1 KHSPSPPPPTPTESR 15 1 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 0 KHS(0.995)PS(0.005)PPPPTPTESR 115.66 0.00077332 20707000 1233.6 1035.5 1346.5 1042.8 1137.8 1577.7 1497 2260.8 1306 1314.4 TRUE FALSE FALSE 1135.959258 1125.004006 1396.402475 1038.48517 1124.232478 1250.467236 1539.001791 2950.107513 1162.735067 1360.075302 0.835217915 0.827163028 1.026709677 0.76354976 0.82659576 0.919410296 1.131556311 2.1690766 0.85490492 1 10.40947081 -4.237795959 2.51615122 0.903152557 2.490439651 0.958769718 0.079755066 0.087734558 0.655872393 0.012748142 0.303621935 5.78E-05 4.237795959 1.587287094 up QSS(ph)PSGSEQLVR ddPTM_HeLa_Curcumin_4h_R1 2 QSSPSGSEQLVR 12 0 O15231-3;H0Y704;O15231-2;H7BZT5;O15231-4;O15231-7;O15231;O15231-8;O15231-6;O15231-9;O15231-5 O15231-3 ZNF185 Zinc finger protein 185 1 0 QS(0.008)S(0.991)PS(0.001)GSEQLVR;QS(0.058)S(0.935)PS(0.007)GSEQLVR ; 206.66 4.49E-09 197348000 7710.4 6834.6 6618.9 6463.7 7312.8 7951.4 7141.5 7424.2 7255.7 6244.9 TRUE FALSE FALSE 7100.113704 7425.35237 6864.202257 6436.954922 7225.599636 6302.190009 7341.87127 9687.804403 6459.767863 6461.90981 1.098763974 1.149095637 1.062255967 0.996138156 1.1181833 0.97528288 1.136176685 1.499216901 0.999668527 1 12.6577449 -4.283410771 3.298097296 1.053578616 1.549525788 0.852534089 0.055799217 0.082663318 1.473079639 0.008012233 0.10070754 5.21E-05 4.283410771 0.495947173 QSS(ph)SSDTDLSLT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 QSSSSDTDLSLTPK 14 0 Q86YS7;H0YFE9;Q86YS7-3 Q86YS7;Q86YS7-3 C2CD5 C2 domain-containing protein 5 2 0 QS(0.131)S(0.602)S(0.072)S(0.184)DT(0.011)DLS(0.08)LT(0.92)PK 128.72 0.00078553 0 1885.3 1571.9 1884.5 1757.3 1566.5 1417.7 1415.2 1108.8 1914.9 1950.6 TRUE FALSE FALSE 1736.076516 1707.768032 1954.341228 1750.028758 1547.820511 1123.653039 1454.906703 1446.868016 1704.840261 2018.383205 0.860132264 0.846106937 0.968270655 0.867044848 0.766861569 0.556709468 0.720827789 0.716845053 0.844656385 1 10.97898439 -5.70447078 2.625998508 0.926028855 0.669453227 0.705375161 0.066885532 0.11003505 1.543275074 0.010958485 0.023462917 1.97E-06 5.70447078 -0.256575628 QSS(ph)TPGSLFLSPPAPAPK ddPTM_HeLa_Curcumin_4h_R1 1 QSSTPGSLFLSPPAPAPK 18 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;F6UYG0 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 0 QS(0.089)S(0.717)T(0.089)PGS(0.087)LFLS(0.018)PPAPAPK 80.459 0.0062477 8395300 1304.6 1027.7 976.03 1293.4 1330.2 844.21 798.25 545.54 1049.2 1004.7 TRUE FALSE FALSE 1201.339533 1116.529809 1012.20253 1288.048254 1314.338234 669.1113298 820.6467466 711.8726346 934.105385 1039.61325 1.155563892 1.073985743 0.973633734 1.238968677 1.264256909 0.643615623 0.78937696 0.684747558 0.898512389 1 10.02183121 -5.251747716 24.99674401 1.091139874 0.714259715 0.705131519 0.112690418 265.5067902 684793.5884 0.01480937 0.037237366 5.60E-06 5.251747716 -0.376880159 QSS(ph)VTNVGK ddPTM_HeLa_Curcumin_4h_R1 1 QSSVTNVGK 9 0 Q6P4F7-3;Q6P4F7 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 0 QS(0.04)S(0.957)VT(0.002)NVGK 99.752 0.013275 5816200 3752.1 2551 3069 4101.3 3253.9 3168.4 2995.1 3770 3517.5 2941.1 TRUE FALSE FALSE 3455.117326 2771.497073 3182.73984 4084.329907 3215.099368 2511.238125 3079.134445 4919.455645 3131.63905 3043.303006 1.135318211 0.910687193 1.045817598 1.342071394 1.056450627 0.825168614 1.011773865 1.616485652 1.029026372 1 11.57142227 -4.258867664 24.88240739 1.053197181 1.616485866 0.639798453 0.129496492 112.6268094 1089641.639 0.018287487 0.166121596 5.51E-05 4.258867664 0.563288685 QSSCGK(ac)FQTK ddPTM_HeLa_Curcumin_4h_R1 2 QSSCGKFQTK 10 1 Q9GZR7-2;Q9GZR7 Q9GZR7-2 DDX24 ATP-dependent RNA helicase DDX24 0 1 ; QSSCGK(1)FQTK;QSSCGK(1)FQTK 158.56 8.36E-09 29278000 7127.6 5768.3 5905.5 5296.7 4784.3 5861.5 4362.5 3454 4490.1 5414.6 FALSE TRUE FALSE 6563.442939 6266.886149 6124.363025 5274.783659 4727.250347 4645.758827 4484.900009 4507.1087 3997.547264 5602.756947 1.171466655 1.118536144 1.093098109 0.94146216 0.843736466 0.82919157 0.800480915 0.804444801 0.713496463 1 12.45192119 -5.989739374 2.136002862 1.087776198 0.813906655 0.293894212 0.125336155 0.106257059 0.970393829 0.01034158 0.020129055 1.02E-06 5.989739374 -0.273869542 QSSEAEIQAK ddPTM_HeLa_Curcumin_4h_R1 2 QSSEAEIQAK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 169.65 1.92E-12 6060400 4098.2 3519.6 3514.8 3130.8 3576.7 4684.3 3285.8 2533.9 3339 3330.7 FALSE FALSE TRUE 3773.823146 3823.818541 3645.06158 3117.845579 3534.050189 3712.723377 3377.990705 3306.474445 2972.720054 3446.441577 1.094991185 1.109497566 1.057630457 0.904656443 1.025420019 1.077262821 0.980138682 0.959387929 0.862547641 1 11.75089184 QSSFEPEFVIS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 QSSFEPEFVISPR 13 0 A0A0A0MSU3;Q9H9A7 A0A0A0MSU3 RMI1 RecQ-mediated genome instability protein 1 1 0 QSSFEPEFVIS(1)PR 142.19 0.00089694 1735700 1045.9 818.34 870.76 1209.6 1096.7 1285.4 797.12 545.84 808.77 1048.2 TRUE FALSE FALSE 963.1159114 889.0736631 903.0311316 1204.594996 1083.622569 1018.793551 819.4850419 712.2641033 720.0499544 1084.624872 0.887971442 0.819706136 0.832574612 1.110609785 0.999075899 0.939304986 0.755546976 0.656691656 0.663870038 1 10.08298044 -4.642251868 3.07535464 0.944245596 0.670457273 0.284639761 0.1200543 0.145090624 2.594176068 0.012584089 0.062961806 2.28E-05 4.642251868 -0.273788323 QSSGAS(ph)SSSFSSSR ddPTM_HeLa_Curcumin_4h_R1 2 QSSGASSSSFSSSR 14 0 A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8Y5G6;A0A2R8YFR4;A0A0D9SFB3;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;A0A0D9SF53;A0A2R8YF78;F6S8Q4;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;A0A0J9YVQ7;A0A087WVZ1 A0A2R8YCW1 DDX3X ATP-dependent RNA helicase DDX3X 1 0 QSSGAS(0.413)S(0.413)S(0.023)S(0.133)FS(0.005)S(0.014)SR;QSS(0.001)GAS(0.367)S(0.367)S(0.061)S(0.202)FS(0.001)S(0.001)SR ; 100.68 0.0050075 42324000 5430.5 4226.1 5332.4 4206.9 5571.9 9687.5 7762.5 4956.5 5615.3 4842 TRUE FALSE FALSE 5000.670195 4591.385253 5530.023435 4189.492962 5505.458732 7678.203299 7980.294858 6467.714033 4999.315639 5010.25914 0.998086138 0.916396762 1.103740002 0.836182889 1.098837122 1.532496241 1.592790839 1.290894114 0.997815781 1 12.29066951 -5.353077375 4.291439536 0.990270252 1.484026819 0.835375443 0.098303147 0.056140359 1.826539232 0.012627364 0.029523305 4.44E-06 5.353077375 0.493756567 QSSGASSSS(ph)FSSSR ddPTM_HeLa_Curcumin_4h_R1 2 QSSGASSSSFSSSR 14 0 A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8Y5G6;A0A2R8YFR4;A0A0D9SFB3;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;A0A0D9SF53;A0A2R8YF78;F6S8Q4;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;A0A0J9YVQ7;A0A087WVZ1 A0A2R8YCW1 DDX3X ATP-dependent RNA helicase DDX3X 1 0 QSSGAS(0.001)S(0.001)S(0.004)S(0.994)FSSSR;QSSGAS(0.142)S(0.035)S(0.018)S(0.773)FS(0.032)SSR ; 198.61 1.37E-06 38850000 3768.6 3204.6 3756.7 3587.3 4043.1 7784.9 5228.1 3863.4 3853.1 3310.1 TRUE FALSE FALSE 3470.311333 3481.591345 3895.926607 3572.456703 3994.888673 6170.223986 5374.786415 5041.332875 3430.42457 3425.125729 1.013192393 1.016485706 1.137455065 1.043014764 1.166348038 1.801459121 1.5692231 1.471867976 1.00154705 1 11.74194123 -5.418552059 4.497522947 1.022846278 1.606484061 0.899114031 0.086681608 0.047050218 1.566820903 0.012408275 0.028430273 3.81E-06 5.418552059 0.583637782 QSSGASSSSFSSSR ddPTM_HeLa_Curcumin_4h_R1 2 QSSGASSSSFSSSR 14 0 A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8Y5G6;A0A2R8YFR4;A0A0D9SFB3;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;A0A0D9SF53;A0A2R8YF78;F6S8Q4;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;A0A0J9YVQ7;A0A087WVZ1 A0A2R8YCW1 DDX3X ATP-dependent RNA helicase DDX3X 0 0 ; ; 222.81 1.88E-27 2520700 196.28 0 311.45 0 69.97 278.93 216.168 226.869 0 266.024 FALSE FALSE TRUE 180.7442309 0 322.992611 0 69.13565345 221.0767738 222.2330923 296.0403137 0 275.2683142 0.656611101 0 1.173373739 0 0.251157325 0.803131935 0.807332631 1.075460917 0 1 8.104694742 -8.654787397 0.975929419 0.966519328 0.585583301 0 0.491385247 0.725866562 1.393652527 0.14981947 0.075743844 2.21E-09 8.654787397 -0.380936027 QSSGS(ph)ATNVASTPDNR ddPTM_HeLa_Curcumin_4h_R1 1 QSSGSATNVASTPDNR 16 0 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 0 QS(0.17)S(0.17)GS(0.658)AT(0.002)NVASTPDNR 139.81 0.0003973 10287000 603.86 764.01 623.36 604.37 577.82 540.38 599.32 555.59 810.26 695.01 TRUE FALSE FALSE 556.0638438 830.04762 646.46227 601.8692771 570.9298739 428.2990967 616.1353062 724.9868334 721.3765052 719.1615458 0.773211314 1.154187991 0.898911064 0.836904143 0.79388265 0.59555339 0.856741173 1.00810011 1.003079919 1 9.49017207 -6.163379199 3.553038098 0.914352062 0.802944326 0.185259511 0.134540094 0.437382872 10.34613097 0.022427939 0.038287815 6.86E-07 6.163379199 -0.111407736 QSSIFGGADVGFSGGIPS(ph)PDKGHR ddPTM_HeLa_Curcumin_4h_R1 1 QSSIFGGADVGFSGGIPSPDKGHR 24 1 E9PR71;Q9P2Y5-2;Q9P2Y5 E9PR71 UVRAG UV radiation resistance-associated gene protein 1 0 QSSIFGGADVGFS(0.015)GGIPS(0.985)PDKGHR 71.881 0.00037744 14409000 642.83 752.21 663.9 547.13 588.26 1032.6 525.8 298.94 653.43 572.9 TRUE FALSE FALSE 591.9493272 817.2276806 688.504718 544.866121 581.2453837 818.4271202 540.5525329 390.0854298 581.7503638 592.8082324 0.998551125 1.37857006 1.161429077 0.919127116 0.980494791 1.380593378 0.911850584 0.658029711 0.981346635 1 9.211421672 -4.517872786 24.97489825 1.054597042 0.721484797 0.394243646 0.161864946 152.5288676 760960.5316 0.022801078 0.090636193 3.03E-05 4.517872786 -0.333112246 QSSLAEPVS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 QSSLAEPVSPSK 12 0 E7EMD6;O43572 E7EMD6 AKAP10 "A-kinase anchor protein 10, mitochondrial" 1 0 QSSLAEPVS(0.985)PS(0.015)K 140.93 0.0011506 15053000 4159.8 3645.4 4406.8 4336.3 4485.7 4060.3 3489.8 3672.3 4057.4 3634.8 TRUE FALSE FALSE 3830.547441 3960.492132 4570.119885 4318.35754 4432.210957 3218.148011 3587.714396 4791.967365 3612.313371 3761.109029 1.018462217 1.053011785 1.215099017 1.14816069 1.178431926 0.855638054 0.953898004 1.274083609 0.960438356 1 11.87694241 -7.105541012 4.263805879 1.008975327 1.09414132 0.145038211 0.116837018 0.423474962 13.14433496 0.019722383 0.024451969 7.84E-08 7.105541012 0.085165994 QSSSSDTDLSLT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 QSSSSDTDLSLTPK 14 0 Q86YS7;H0YFE9;Q86YS7-3 Q86YS7;Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 0 QSS(0.004)S(0.038)S(0.006)DT(0.009)DLS(0.029)LT(0.914)PK 129.05 0.0032556 19703000 2855.4 3383.1 3104.9 2840.9 2507.4 2643.3 1956.3 1331.3 3405.6 2982.6 TRUE FALSE FALSE 2629.392077 3675.520089 3219.970325 2829.145109 2477.500893 2095.049784 2011.188513 1737.207241 3032.0142 3086.245128 0.851971236 1.19093589 1.043329415 0.91669488 0.802755708 0.678834537 0.651661948 0.562886994 0.982428185 1 11.59163694 -5.415141669 1.634390107 0.960056667 0.609946065 0.77296596 0.088900428 0.176250545 0.90543377 0.015843843 0.048689705 3.84E-06 5.415141669 -0.350110602 QSSSSRDDNMFQIGK ddPTM_HeLa_Curcumin_4h_R1 1 QSSSSRDDNMFQIGK 15 1 P53999 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 0 0 87.083 0.010083 4441500 1248.2 723.72 1076.3 1021.4 814.28 1249.5 1075 884.7 1132.4 987.1 FALSE FALSE TRUE 1149.403653 786.275132 1116.188625 1017.173717 804.5702428 990.3396152 1105.161607 1154.440957 1008.178553 1021.401652 1.125319948 0.769800138 1.092800881 0.995860655 0.787711907 0.969588813 1.082004915 1.130251704 0.987053968 1 9.996334582 QSSSSTTSQGGVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 QSSSSTTSQGGVKR 14 1 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 0 1 ; QSSSSTTSQGGVK(1)R;QSSSSTTSQGGVK(1)R 243.37 4.34E-49 1755020 0 0 0 0 80.492 72.511 0 65.904 210.193 67.635 FALSE TRUE FALSE 0 0 0 0 79.53218547 57.47140123 0 85.99782622 187.1353538 69.98531122 0 0 0 0 1.136412543 0.821192336 0 1.228798225 2.673923292 1 6.12898025 -9.534748049 1.332995784 0.995521219 0.337278456 0.254501875 0.718209278 0.562346785 1.808611437 0.327294783 0.080352743 2.92E-10 9.534748049 -0.658242764 QSSTPGSLFLS(ph)PPAPAPK ddPTM_HeLa_Curcumin_4h_R1 2 QSSTPGSLFLSPPAPAPK 18 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;F6UYG0 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 0 QSSTPGSLFLS(1)PPAPAPK;QSSTPGSLFLS(1)PPAPAPK ; 178.22 9.00E-07 35167000 6345.9 4953.7 4934 5638.2 5745.1 7683.5 5256.2 2425.7 6186.2 4919.8 TRUE FALSE FALSE 5843.615319 5381.875755 5116.85838 5614.870622 5676.593435 6089.855489 5403.674826 3165.284763 5507.589337 5090.762684 1.147886021 1.057184569 1.005126088 1.102952734 1.115077207 1.196256017 1.061466653 0.621770245 1.081879019 1 12.3136661 -4.263275231 5.877428671 1.079692301 0.608856887 0.856214051 0.056990611 0.043706637 6.871875176 0.009694694 0.082171932 5.45E-05 4.263275231 -0.470835414 QSSVTQVTEQS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 QSSVTQVTEQSPK 13 0 Q14966-3;Q14966;C9JWN0;Q14966-2;Q14966-6;Q14966-4 Q14966-3 ZNF638 Zinc finger protein 638 1 0 QSSVTQVTEQS(1)PK;QSSVTQVT(0.001)EQS(0.999)PK;QSSVTQVTEQS(1)PK ;; 233.28 9.71E-20 32106800 7888.1 6419.7 6796.5 7781.5 7688.5 10586.2 10335 4590.6 8191.4 6446.3 TRUE FALSE FALSE 7263.748562 6974.590262 7048.384269 7749.302215 7596.819659 8390.502789 10624.97228 5990.252807 7292.823914 6670.308445 1.088967418 1.045617353 1.056680411 1.161760701 1.138900805 1.257888276 1.592875708 0.898047348 1.093326339 1 12.70353776 -5.781563814 1.380397458 1.043792865 1.275017108 0.189580433 0.16048611 0.389919682 1.486965837 0.02320508 0.058622859 1.65E-06 5.781563814 0.231224242 QSSYSQQPYNNQGQQQNMESSGS(ph)QGGR ddPTM_HeLa_Curcumin_4h_R1 1 QSSYSQQPYNNQGQQQNMESSGSQGGR 27 0 Q92804-2;Q92804;A0A075B7F2 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 1 0 QSSYSQQPYNNQGQQQNMES(0.023)S(0.131)GS(0.845)QGGR 78.531 4.02E-05 1755200 310.49 258.34 339.97 236.2 535.03 418.55 465.63 439.65 323.08 405.54 TRUE FALSE FALSE 285.9143889 280.6697585 352.5695873 235.222667 528.6501167 331.738012 478.6943246 573.6972611 287.6389323 419.6324848 0.681344746 0.668846595 0.840186592 0.560544466 1.259793119 0.790544164 1.140746586 1.367142159 0.685454398 1 8.712982555 -3.992999453 0.850850198 0.824876347 1.928795718 0.490339674 0.188028127 2.405476222 0.942198444 0.030808119 2.760028008 0.000101625 3.992999453 1.103919371 QSTLYSFFPKS(ph)PALSDANK ddPTM_HeLa_Curcumin_4h_R1 1 QSTLYSFFPKSPALSDANK 19 1 F8WAX8;A0A087WWJ1;P52701-2;P52701;F8W7G9;P52701-3 F8WAX8 MSH6 DNA mismatch repair protein Msh6 1 0 QSTLY(0.005)S(0.024)FFPKS(0.966)PALS(0.005)DANK 76.889 0.0025667 41790000 1253.3 739.16 736.08 1057.5 972.94 1073.6 767.03 450.29 961.27 1037.1 TRUE FALSE FALSE 1154.099983 803.0496968 763.3597723 1053.124345 961.3383259 850.923258 788.5507974 587.5813481 855.821086 1073.139148 1.075442998 0.748318332 0.71133345 0.981349294 0.895818895 0.792929099 0.734807596 0.547535098 0.797493119 1 10.06762144 -3.39519876 0.270834741 1.047217295 5.41E-12 0.241338449 0.131632677 7.767827726 0.298989863 0.064167125 2.94161366 0.000402533 3.39519876 -1.047217295 QSVFPFESGKPFK ddPTM_HeLa_Curcumin_4h_R1 2 QSVFPFESGKPFK 13 1 G3V3R6;P17931 G3V3R6 LGALS3 Galectin;Galectin-3 0 0 ; ; 115.12 0.00046226 2471170 2051.55 1663.36 2081.71 1384.18 2046.98 2478.8 1844.24 1919.55 1606.24 1505.58 FALSE FALSE TRUE 1889.167653 1807.133427 2158.860004 1378.45263 2022.5711 1964.668938 1895.984411 2504.811958 1430.039491 1557.898793 1.212638242 1.159981274 1.385751124 0.884815263 1.29826861 1.261101778 1.217013852 1.607814301 0.917928364 1 10.6053858 -1 0.511176 1.111243642 16.08518889 0.471156092 0.151649252 67.06996357 0.625396437 0.027531604 1090.618671 0.1 1 14.97394525 QT(ph)DLELSPLTK ddPTM_HeLa_Curcumin_4h_R1 1 QTDLELSPLTK 11 0 J3KTC5;Q8WVK7 J3KTC5 SKA2 Spindle and kinetochore-associated protein 2 1 0 QT(0.988)DLELS(0.011)PLT(0.001)K 153.54 3.87E-05 0 1108.6 767.95 1131.2 1191.4 1547.9 1936.6 1607.1 1568.9 1320.2 1100 TRUE FALSE FALSE 1020.85314 834.3281761 1173.123267 1186.470302 1529.442303 1534.92733 1652.190901 2047.250388 1175.377363 1138.224918 0.896881736 0.73300818 1.030660328 1.042386512 1.34370833 1.34852726 1.451550458 1.798634308 1.032640688 1 10.15256995 -4.981574686 0.726340874 0.931667492 1.849703204 0.869281407 0.107586185 0.33915838 0.217082909 0.019167951 0.208265595 1.04E-05 4.981574686 0.918035711 QT(ph)SLVS(ph)SRREPPPY(ph)GY(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 QTSLVSSRREPPPYGYR 17 2 G3V3A4;Q13573;G3V5R3 G3V3A4 SNW1 SNW domain-containing protein 1 4 0 QT(0.52)S(0.52)LVS(0.867)S(0.098)RREPPPY(0.997)GY(0.997)R 44.807 0.019188 29752000 2756.2 2842.2 2504.5 3225.8 2538.7 182.28 749.55 938 2302.2 2297.9 TRUE FALSE FALSE 2538.043862 3087.867103 2597.318973 3212.452494 2508.427661 144.4730733 770.5803557 1223.991882 2049.65442 2377.751854 1.067413262 1.298649856 1.092342319 1.351046153 1.054957714 0.060760366 0.324079384 0.514768553 0.862013593 1 11.21538245 -5.274368877 24.22775371 1.083585901 0.302290451 0.82918617 0.167028354 134.66828 252346.3231 0.022680718 0.051039736 5.32E-06 5.274368877 -0.78129545 QTAEETGLT(ph)PLETSR ddPTM_HeLa_Curcumin_4h_R1 2 QTAEETGLTPLETSR 15 0 Q5T8C6;Q13042-4;Q13042-3;Q13042-2;Q13042 Q5T8C6 CDC16 Cell division cycle protein 16 homolog 1 0 QT(0.001)AEET(0.025)GLT(0.956)PLET(0.015)S(0.003)R;QTAEET(0.003)GLT(0.997)PLETSR ; 145.79 0.0014043 21819000 3096.7 2417.6 2433.3 2654.2 3132.6 3370.6 3106.5 2697.4 2682.9 2503.2 TRUE FALSE FALSE 2851.592927 2626.566571 2523.480239 2643.217624 3095.245791 2671.499566 3193.660029 3519.824843 2388.592582 2590.186014 1.100922062 1.014045539 0.974246724 1.020474055 1.194989771 1.031392939 1.232984817 1.358908134 0.922170288 1 11.33883999 -3.791942503 0.799969777 1.04115786 1.8466788 0.701503894 0.070678317 1.843918259 0.509487227 0.01021708 1.573940886 0.000161457 3.791942503 0.80552094 RGS(ph)PVPPVPER ddPTM_HeLa_Curcumin_4h_R1 1 RGSPVPPVPER 11 1 J3KPS2;A0A494C1T9;Q6ZRV2 J3KPS2 FAM83H Protein FAM83H 1 0 RGS(1)PVPPVPER 87.824 0.0092543 15796000 2549 2142.3 1823.4 2358.1 2046.4 2207.2 1707.7 378.04 2144.5 2015.8 TRUE FALSE FALSE 2347.24396 2327.470866 1890.976808 2348.342807 2021.998017 1749.40184 1755.613466 493.3026557 1909.253715 2085.8489 1.125318311 1.115838672 0.906574205 1.125845121 0.969388538 0.838700176 0.841678161 0.236499708 0.91533654 1 11.02641894 -4.273690947 1.24273516 1.051514333 4.32E-23 0.840526872 0.098652588 0.361128212 0.469069529 0.013231865 0.482482474 5.32E-05 4.273690947 -1.051514333 down QTDFEHR ddPTM_HeLa_Curcumin_4h_R1 3 QTDFEHR 7 0 Q01813;Q01813-2;B1APP6 Q01813 PFKP "ATP-dependent 6-phosphofructokinase, platelet type" 0 0 ;; ;; 185.55 0.0022111 29443070 12504.9 16825.4 11563 9723.51 9819.64 15173.4 9695.5 9583.9 10670.7 12994.6 FALSE FALSE TRUE 11515.12397 18279.7126 11991.53495 9683.276692 9702.547206 12026.2658 9967.529636 12505.98699 9500.150907 13446.16138 0.856387458 1.359474432 0.891818461 0.720151753 0.721584914 0.894401417 0.741291834 0.930078603 0.706532566 1 13.71490675 -6.520031991 24.99447422 0.970111662 0.799588678 0.204017899 0.166347294 131.456165 1154186.757 0.023383101 0.033424551 3.02E-07 6.520031991 -0.170522984 QTDLELS(ph)PLTKEEK ddPTM_HeLa_Curcumin_4h_R1 1 QTDLELSPLTKEEK 14 1 J3KTC5;Q8WVK7 J3KTC5 SKA2 Spindle and kinetochore-associated protein 2 1 0 QT(0.001)DLELS(0.982)PLT(0.017)KEEK 68.639 0.015334 19568000 4644.2 4028.3 3723.9 4292.8 4402.9 7142.4 6737.1 6829.9 6458.5 5318 TRUE FALSE FALSE 4276.606669 4376.488302 3861.91101 4275.037531 4350.398293 5660.985729 6926.124894 8912.305069 5750.018708 5502.800104 0.777169185 0.79532024 0.701808341 0.776884032 0.790579016 1.028746388 1.258654642 1.619594552 1.044925965 1 12.42595021 -4.520593556 1.565194939 0.855324262 1.710495911 0.851027854 0.103817162 0.204095028 0.663899836 0.017123078 0.228653777 3.02E-05 4.520593556 0.855171649 QTELFAHFIQPAAQKT(ph)PT(ph)SPLK ddPTM_HeLa_Curcumin_4h_R1 1 QTELFAHFIQPAAQKTPTSPLK 22 1 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 2 0 QTELFAHFIQPAAQKT(0.907)PT(0.546)S(0.546)PLK 48.616 0.017468 21285000 1349.3 1365 1633.7 1643.1 1660.3 2295.5 2047.8 1739.6 1955.4 2014.9 TRUE FALSE FALSE 1242.501481 1482.984518 1694.246359 1636.301288 1640.502007 1819.387424 2105.255757 2269.996032 1740.897512 2084.917625 0.595947517 0.71129166 0.812620287 0.784827788 0.786842601 0.872642354 1.009754885 1.088770129 0.834995825 1 11.02577467 -4.748805424 1.868732619 0.794368247 1.091953608 0.54288384 0.095420781 0.373875114 2.319434031 0.021843629 0.138907401 1.78E-05 4.748805424 0.297585361 QTELFAHFIQPS(ph)AQKS(ph)PTSPLNMK ddPTM_HeLa_Curcumin_4h_R1 1 QTELFAHFIQPSAQKSPTSPLNMK 24 1 A0A0A0MRP6;B7ZLQ5;P28370-2;P28370 A0A0A0MRP6 SMARCA1 Probable global transcription activator SNF2L1 2 0 QTELFAHFIQPS(0.954)AQKS(0.349)PT(0.349)S(0.349)PLNMK 49.106 0.020275 11259000 1859.6 1294.7 1263.1 1419.6 1414.8 1792 1726.9 864.09 1741.3 1542 TRUE FALSE FALSE 1712.410698 1406.608099 1309.911597 1413.726071 1397.929434 1420.319 1775.352166 1127.547063 1550.283747 1595.584385 1.073218511 0.881562963 0.820960401 0.886024008 0.876123787 0.890155991 1.112665794 0.706667146 0.971608748 1 10.63986919 -7.2535719 24.17226418 1.034575408 0.888785002 0.27322125 0.097347429 305.8428468 939680.0403 0.01509117 0.018296906 5.58E-08 7.2535719 -0.145790406 QTESTSFLEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 QTESTSFLEKK 11 1 G3V5Z7;P60900-2;P60900;G3V295;P60900-3 G3V5Z7 PSMA6 Proteasome subunit alpha type;Proteasome subunit alpha type-6 0 1 ; QTESTSFLEK(1)K;QTESTSFLEK(1)K 173.04 1.43E-09 4559000 1272.54 1122.41 1040.41 1202.85 1306.41 1924.39 1370.77 1455.77 1866.9 1258.95 FALSE TRUE FALSE 1171.817116 1219.426119 1078.96851 1197.872925 1290.831914 1525.249822 1409.230117 1899.627571 1662.105741 1302.698419 0.89953062 0.93607707 0.828256559 0.919532033 0.990890827 1.170838776 1.081777714 1.45822513 1.275894495 1 10.34728742 -2.958396842 0.70913666 0.939340353 4.18757343 0.535836991 0.125757725 4.442006891 0.381146442 0.012125921 17.69045628 0.001100533 2.958396842 3.248233077 QTETEMLYGS(ph)APRTPSK ddPTM_HeLa_Curcumin_4h_R1 1 QTETEMLYGSAPRTPSK 17 1 G3V3N7;O43663-3;O43663-2;O43663-4;O43663;H0YL53 G3V3N7 PRC1 Protein regulator of cytokinesis 1 1 0 QTET(0.009)EMLY(0.089)GS(0.864)APRT(0.037)PS(0.001)K 111.78 0.0020728 7883500 3236.4 2178.8 2150.7 2695.5 1911.5 4018.9 2709.7 1187.9 3611.8 3187.8 TRUE FALSE FALSE 2980.235525 2367.125763 2230.406834 2684.346735 1888.706611 3185.334838 2785.726889 1550.085242 3215.594576 3298.575813 0.903491596 0.717620542 0.676172676 0.813789613 0.572582447 0.965669737 0.844524136 0.469925607 0.974843314 1 11.68762755 -7.437688052 2.264355535 0.963284865 0.732015708 0.403122941 0.132314111 0.220194161 2.174389333 0.023795329 0.026477361 3.65E-08 7.437688052 -0.231269157 S(ph)MSDVS(ph)AEDVQNLR ddPTM_HeLa_Curcumin_4h_R1 2 SMSDVSAEDVQNLR 14 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424;E9PJ10;E9PK58;E9PLU6 Q8WWI1-3 LMO7 LIM domain only protein 7 2 0 S(0.973)MS(0.027)DVS(1)AEDVQNLR;S(0.963)MS(0.037)DVS(1)AEDVQNLR ; 144.4 0.0015646 9278600 6043.3 4764.9 5225.7 5284.8 6271.2 6798.6 4350.2 1283.71 5580.4 4815.8 TRUE FALSE FALSE 5564.966428 5176.756724 5419.369039 5262.932898 6196.420036 5388.493724 4472.254904 1675.10727 4968.244081 4983.148692 1.116757049 1.03885255 1.087539099 1.056146068 1.243474843 1.081343154 0.897475709 0.336154382 0.997008998 1 12.28284191 -4.273626006 2.468159025 1.071968468 0.182818804 0.917527991 0.066793471 0.107225986 0.816070292 0.010087611 0.198047218 5.33E-05 4.273626006 -0.889149664 down QTGIET(ph)PNK ddPTM_HeLa_Curcumin_4h_R1 1 QTGIETPNK 9 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 0 QT(0.001)GIET(0.999)PNK 139.76 0.0069683 28383000 4581.3 4046.5 4365 4325.6 4900.6 5463.9 5414.6 3174.3 4055.7 2994.8 TRUE FALSE FALSE 4218.685271 4396.261429 4526.77074 4307.701813 4842.163546 4330.625549 5566.519103 4142.129457 3610.799857 3098.869077 1.36136286 1.418666397 1.460781539 1.390088354 1.562558283 1.397485806 1.796306641 1.336658424 1.165199228 1 11.59752609 -9.060875495 0.278971346 0.78073806 1.571733602 0.594198184 0.128521145 1.387749565 0.16617864 0.375246203 0.080277128 8.69E-10 9.060875495 0.790995542 QTLENERGELANEVK ddPTM_HeLa_Curcumin_4h_R1 1 QTLENERGELANEVK 15 1 P35579 P35579 MYH9 Myosin-9 0 0 74.338 0.019633 6808800 5524.5 3976.9 4226.6 5221.2 4598.3 1299.2 1515.2 2387.3 4683.5 4123.2 FALSE FALSE TRUE 5087.229996 4320.645515 4383.241514 5199.596058 4543.468276 1029.731275 1557.712434 3115.17678 4169.731768 4266.480893 1.192371447 1.012695386 1.027366962 1.218708389 1.064921745 0.241353776 0.365104749 0.730151349 0.977323436 1 12.05883087 -5.274073909 24.2862595 1.090241069 0.437493454 0.813146876 0.137038473 141.0705737 271167.8303 0.019371935 0.043610916 5.32E-06 5.274073909 -0.652747615 QTLSIYQALK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 QTLSIYQALKK 11 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 1 QTLSIYQALK(1)K 152.85 9.45E-08 516940 195.6 223.25 275.77 0 179.41 859.21 474.63 577.82 459.05 221.05 FALSE TRUE FALSE 180.1180536 242.5467352 285.9902788 0 177.2706529 681.0001607 487.9468404 753.994658 408.6933635 228.731471 0.787465113 1.06039949 1.250332005 0 0.775016451 2.977291046 2.133273739 3.296418523 1.786782386 1 7.837511069 -5.264345622 24.99658525 0.860429733 2.735422426 0.735738127 0.50580429 71.23664171 612709.1861 0.055595787 0.129600169 5.44E-06 5.264345622 1.874992693 QTNGCLNGYT(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 QTNGCLNGYTPSR 13 0 A0A2R8Y653;Q9BZX2-2;Q9BZX2 A0A2R8Y653 UCK2 Uridine-cytidine kinase 2 1 0 QTNGCLNGYT(0.88)PS(0.12)R 137.39 0.0033555 20050000 1043.5 1080 804.39 1100.5 1112.2 1334.2 1278.3 557.41 1248.8 963.2 TRUE FALSE FALSE 960.9058739 1173.350388 834.201401 1095.946423 1098.937741 1057.47188 1314.165658 727.361743 1111.809764 996.6711283 0.96411529 1.177269366 0.836987625 1.099606873 1.102608183 1.061003826 1.318554958 0.729791124 1.115523198 1 9.960973727 QTNPSAMEVEEDDPVPEIR ddPTM_HeLa_Curcumin_4h_R1 1 QTNPSAMEVEEDDPVPEIR 19 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 182.02 4.62E-23 0 424.79 368.96 491.07 491.41 639.09 481.44 383.23 329.81 390.48 309.28 FALSE FALSE TRUE 391.1674233 400.8512583 509.2694862 489.3766756 631.4692692 381.5839171 393.9824024 430.3675507 347.6453209 320.027457 1.222293321 1.252552709 1.591330603 1.529170904 1.973172162 1.192347434 1.231089376 1.34478321 1.08629842 1 8.322051877 -7.497076663 1.047372632 1.064167132 1.470295848 0.378755163 0.213679499 0.358387572 0.794091651 0.051701304 0.054641092 3.18E-08 7.497076663 0.406128716 QTNPSAMEVEEDDPVPEIRR ddPTM_HeLa_Curcumin_4h_R1 2 QTNPSAMEVEEDDPVPEIRR 20 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 ; ; 94.281 0.00087474 26491000 1160.43 1211.71 1294.82 1076.76 1305.14 1464.32 984.72 904.1 1536.73 1414.34 FALSE FALSE TRUE 1068.580741 1316.444813 1342.807168 1072.304652 1289.577058 1160.603526 1012.348593 1179.755928 1368.154564 1463.48821 0.73016013 0.899525397 0.917538768 0.732704675 0.881166687 0.793039205 0.69173676 0.806126022 0.934858617 1 10.51519541 -9.459041217 1.086356463 1.004791825 0.801367954 0.42166682 0.074022287 0.361674585 0.733863621 0.058238305 0.013086612 3.48E-10 9.459041217 -0.203423871 QTPS(ph)PDVVLR ddPTM_HeLa_Curcumin_4h_R1 3 QTPSPDVVLR 10 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 QT(0.251)PS(0.749)PDVVLR;QT(0.167)PS(0.833)PDVVLR;QT(0.032)PS(0.968)PDVVLR ;; 114.87 0.0055108 364881000 8906.2 8312.8 8327.1 8273.1 9660.5 9956.2 7899.1 6471.1 9323.7 8014.3 TRUE FALSE FALSE 8201.264872 9031.321391 8635.709651 8238.868104 9545.304847 7891.17189 8120.727487 8444.108601 8300.913437 8292.796328 0.988962534 1.089056216 1.041350747 0.99349698 1.151035727 0.95156948 0.979250806 1.01824623 1.000978814 1 13.01764294 -3.862246303 18.14563919 1.010364708 3.515246422 0 0.056836496 3339.232301 485323.9992 0.007602857 36006.29295 0.000137326 3.862246303 2.504881714 QTQS(ph)ASSTLQK ddPTM_HeLa_Curcumin_4h_R1 2 QTQSASSTLQK 11 0 O95819-3;E7EX83;G5E948;C9J840;H7C360;E7ENQ1;H7C0P6;G3XAA2;A0A0D9SG62;A0A0D9SEY1;O95819-4;O95819-2;O95819;O95819-5 O95819-3 MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 1 0 QT(0.313)QS(0.343)AS(0.313)S(0.029)T(0.001)LQK;QTQS(0.521)AS(0.117)S(0.01)T(0.352)LQK ; 173.19 0.00022177 15100100 3708.4 3434.3 3250.9 3491.8 3684.3 4176.8 3366.1 3056.2 3567.8 3535.8 TRUE FALSE FALSE 3414.876227 3731.145589 3371.381214 3477.351857 3640.367129 3310.484598 3460.543707 3988.021311 3176.421266 3658.668787 0.933365775 1.01980961 0.921477567 0.95044183 0.994997728 0.904833094 0.945847768 1.09001977 0.868190441 1 11.8371031 -3.145134595 0.001369991 1.924647335 1.83E-08 0 0.062376903 3205994.089 503.735683 349065.5728 358672.6296 0.000715921 3.145134595 -1.924647317 QTQSESSNYDS(ph)ELEK ddPTM_HeLa_Curcumin_4h_R1 1 QTQSESSNYDSELEK 15 0 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6;A0A096LNW1 P46100-5 ATRX Transcriptional regulator ATRX 1 0 QTQSESSNYDS(1)ELEK 185.28 2.44E-05 6846800 2552.3 2302.7 2628.3 2779.5 2839.1 2985.3 2752.9 1639.8 2117.8 2014.4 TRUE FALSE FALSE 2350.282762 2501.735127 2725.70711 2767.999165 2805.245587 2366.115129 2830.138965 2139.767471 1885.482638 2084.40025 1.12755828 1.200218205 1.307669729 1.327959525 1.345828656 1.135153927 1.357771361 1.026562663 0.904568419 1 11.02541662 -7.696123861 0.969416831 1.030480175 1.25665821 0.508515927 0.107201111 0.280872057 0.553144998 0.023981917 0.022556535 2.01E-08 7.696123861 0.226178034 QTQSESSNYDS(ph)ELEKEIK ddPTM_HeLa_Curcumin_4h_R1 1 QTQSESSNYDSELEKEIK 18 1 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6;A0A096LNW1 P46100-5 ATRX Transcriptional regulator ATRX 1 0 QTQSES(0.001)S(0.001)NYDS(0.998)ELEKEIK 93.712 0.00098933 22930000 2603.1 1808.2 1927.3 2287 2097.3 2636.6 2588.8 1371.7 2698.9 2323.3 TRUE FALSE FALSE 2397.061888 1964.492751 1998.727433 2277.537 2072.291067 2089.739439 2661.434761 1789.925015 2402.837422 2404.034502 0.99709962 0.817164957 0.831405469 0.947381162 0.862005543 0.869263498 1.107070118 0.744550469 0.999502054 1 11.23124189 -7.296416461 21.1674414 0.998630468 0.890525023 0.254932641 0.09032175 95.84550285 58003.32239 0.014317609 0.016373687 5.05E-08 7.296416461 -0.108105445 SIS(ph)ADDDLQESSR ddPTM_HeLa_Curcumin_4h_R1 3 SISADDDLQESSR 13 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A2ABK4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 0 S(0.001)IS(0.999)ADDDLQESSR;S(0.148)IS(0.85)ADDDLQES(0.001)SR;S(0.013)IS(0.987)ADDDLQESSR ;; 173.33 0.00020647 690740000 4017.56 3376.34 3813.73 4356.9 3787.72 4879.24 5452 9950.5 3858.37 3768.34 TRUE FALSE FALSE 3699.565887 3668.175785 3955.070189 4338.872302 3742.553913 3867.230624 5604.968447 12984.36164 3435.116464 3899.289535 0.948779477 0.940729267 1.014305338 1.112734067 0.959804057 0.991778269 1.437433255 3.329930114 0.880959578 1 11.92899557 -4.237302815 2.434695645 0.984805959 3.954118469 0.992870465 0.059527747 0.03058223 0.208377003 0.007828359 0.193758858 5.79E-05 4.237302815 2.96931251 up QTSST(ph)PSSLALTSASR ddPTM_HeLa_Curcumin_4h_R1 1 QTSSTPSSLALTSASR 16 0 H0Y2V6;Q5SW79;Q5SW79-3;Q5SW79-2 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 0 QT(0.001)S(0.001)S(0.08)T(0.916)PS(0.001)SLALTSASR 102.39 0.0066334 3211700 1366.1 1230.5 1107.6 1196.3 1440 2142 1968.3 911.33 1127.4 1166.1 TRUE FALSE FALSE 1257.971743 1336.858937 1148.64863 1191.350028 1422.82894 1697.725055 2023.525201 1189.190322 1003.727041 1206.621888 1.042556708 1.107935261 0.951954081 0.987343292 1.179183765 1.407006678 1.677016819 0.985553414 0.831848859 1 10.23675794 -5.478361824 3.248049254 1.020709328 1.385960999 0.473374497 0.172271894 0.140918509 2.975098215 0.021246352 0.049305015 3.32E-06 5.478361824 0.365251672 QTVAVGVIK ddPTM_HeLa_Curcumin_4h_R1 2 QTVAVGVIK 9 0 A0A2U3TZH3;Q05639;Q5VTE0;P68104;A0A087WVQ9 A0A2U3TZH3;Q5VTE0 EEF1A2;EEF1A1P5;EEF1A1 Elongation factor 1-alpha 2;Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1 0 0 ; ; 152.11 8.87E-07 81160000 14528.1 10936.8 13952.5 12838.5 13473.2 15860.2 11978 13227.3 12776.6 12222.6 FALSE FALSE TRUE 13378.18556 11882.12826 14469.59192 12785.37769 13312.54089 12570.61574 12314.07044 17260.24288 11375.03895 12647.33444 1.057786968 0.939496644 1.144082335 1.01091481 1.052596573 0.993934002 0.973649467 1.364733649 0.899402083 1 13.62654573 -4.256096104 24.99750258 1.025420187 1.364733791 0.71917546 0.06607456 184.6766277 863947.2034 0.006816775 0.078975983 5.55E-05 4.256096104 0.339313604 QTVAVGVIK(ac)AVDKK ddPTM_HeLa_Curcumin_4h_R1 2 QTVAVGVIKAVDKK 14 2 Q5VTE0;P68104;A0A087WVQ9 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1 0 1 ; QTVAVGVIK(0.999)AVDK(0.001)K;QTVAVGVIK(1)AVDKK 115.58 0.00010113 12255000 4851.6 3856.2 3825.7 3893 3915.9 4845.9 4098.8 3916.1 4411.1 4072.8 FALSE TRUE FALSE 4467.590741 4189.512745 3967.483807 3876.891798 3869.20545 3840.805715 4213.801297 5110.100862 3927.213366 4214.329497 1.060095264 0.99411134 0.941427055 0.919930869 0.918107009 0.911368159 0.999874666 1.212553709 0.931871456 1 12.0410874 -10.33346602 9.646389697 0.999885589 1.007782808 0 0.088891754 1.764379726 1279.600866 0.082887778 0.012520107 4.64E-11 10.33346602 0.007897219 QTVDK(ac)VMGIPK ddPTM_HeLa_Curcumin_4h_R1 1 QTVDKVMGIPK 11 1 Q14676;Q14676-3 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 0 1 QTVDK(1)VMGIPK 106.16 0.0057515 1372400 811.08 618.97 656.58 853.05 705.54 879.03 449.76 936.55 972.74 771.59 FALSE TRUE FALSE 746.8821622 672.4710087 680.9134324 849.5203051 697.1268963 696.7092693 462.3790551 1222.099784 866.0328557 798.4026951 0.935470492 0.842270464 0.852844607 1.064024847 0.873151983 0.872628905 0.579130128 1.530680935 1.084706829 1 9.64097278 -8.732665919 1.02724538 0.993832951 0.926162179 0.01483535 0.230586947 2.162197123 4.564524946 0.082488088 0.040456742 1.85E-09 8.732665919 -0.067670772 IVEMSTSK(ac)TGK ddPTM_HeLa_Curcumin_4h_R1 6 IVEMSTSKTGK 11 1 I3L397;I3L504;P63241;P63241-2;F8WCJ1;C9J7B5;C9J4W5;Q9GZV4 I3L397 EIF5A;EIF5A2 Eukaryotic translation initiation factor 5A;Eukaryotic translation initiation factor 5A-1;Eukaryotic translation initiation factor 5A-2 0 1 ;;;;; IVEMSTSK(1)TGK;IVEMSTSK(1)TGK;IVEMSTSK(1)TGK;IVEMSTSK(1)TGK;IVEMSTSK(1)TGK;IVEMSTSK(1)TGK 259.08 4.54E-65 548938700 21313.1 16247.9 15635.3 16690 16226.8 22514.7 12377.09 4475.47 20148.8 16100.9 FALSE TRUE FALSE 19626.14565 17652.29608 16214.75797 16620.9412 16033.30601 17844.89743 12724.35783 5840.0202 17938.52705 16660.40508 1.178011312 1.059535827 0.973251124 0.997631278 0.962359915 1.071096252 0.763748407 0.350532906 1.07671614 1 14.02413586 -4.267398527 1.532069199 1.064346065 0.068112874 0.911237307 0.06620303 0.273406799 0.58810954 0.012475646 0.408110237 5.40E-05 4.267398527 -0.996233192 down QTVLRVVGPCWT(ph)CGCGT(ph)DT(ph)NFEVK ddPTM_HeLa_Curcumin_4h_R1 1 QTVLRVVGPCWTCGCGTDTNFEVK 24 1 I3L161;I3L3X5;Q9NRY6 I3L161 TMEM256-PLSCR3;PLSCR3 Phospholipid scramblase 3 3 0 QT(0.227)VLRVVGPCWT(0.774)CGCGT(0.999)DT(1)NFEVK 46.953 0.0080318 0 176.57 121.6 57.587 107.71 123.43 282.75 104.46 57.4 0 194.66 TRUE FALSE FALSE 162.5942982 132.1105622 59.72122488 107.2643246 121.9581779 224.1044628 107.3908665 74.90099576 0 201.4244205 0.80722237 0.655881555 0.29649446 0.532528897 0.605478609 1.112598275 0.533157133 0.371856578 0 1 7.654094795 -7.605612207 1.461496733 0.938735318 0.593210741 0 0.361854135 0.315116259 1.371605819 0.045694671 0.046942256 2.48E-08 7.605612207 -0.345524577 QVAEQGGDLS(ph)PAANR ddPTM_HeLa_Curcumin_4h_R1 2 QVAEQGGDLSPAANR 15 0 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 0 QVAEQGGDLS(1)PAANR;QVAEQGGDLS(1)PAANR ; 245.18 2.52E-29 697510000 8859.3 7901.3 7753.3 7783.8 7674.9 8689.3 5648.9 3434.4 9545.7 7520.8 TRUE FALSE FALSE 8158.077057 8584.253164 8040.644118 7751.592698 7583.38183 6887.041231 5807.392931 4481.53275 8498.560592 7782.14724 1.048306695 1.103070001 1.033216652 0.996073765 0.974458796 0.884979559 0.746245574 0.575873549 1.092058571 1 12.92595256 -4.473467142 0.944513166 1.03078741 0.419707087 0.956384939 0.033081976 0.213320923 0.178456791 0.005138836 0.122744116 3.36E-05 4.473467142 -0.611080324 QVAGDAPVEQATAET(ph)ASPVHR ddPTM_HeLa_Curcumin_4h_R1 1 QVAGDAPVEQATAETASPVHR 21 0 A0A087X055;Q92766;Q92766-2;Q92766-4 A0A087X055 RREB1 Ras-responsive element-binding protein 1 1 0 QVAGDAPVEQAT(0.018)AET(0.821)AS(0.161)PVHR 98.292 0.00021016 13844000 2319.5 1572.8 2570.8 2584 3252.5 2824.4 2193 1256.1 2852.5 2467.4 TRUE FALSE FALSE 2135.909127 1708.745824 2666.07611 2573.308093 3213.716062 2238.587602 2254.529678 1639.079108 2539.587887 2553.141966 0.836580635 0.669271763 1.044233397 1.007898553 1.258729873 0.876797151 0.883041252 0.641985103 0.994691216 1 11.31805805 -13.52283772 0.008806543 1.959745585 1.79E-07 0.039320809 0.169824337 69090.43234 49.20608347 6199.538023 4831.089048 3.00E-14 13.52283772 -1.959745407 QVAGDAPVEQATAETAS(ph)PVHR ddPTM_HeLa_Curcumin_4h_R1 1 QVAGDAPVEQATAETASPVHR 21 0 A0A087X055;Q92766;Q92766-2;Q92766-4 A0A087X055 RREB1 Ras-responsive element-binding protein 1 1 0 QVAGDAPVEQATAET(0.024)AS(0.976)PVHR 152.26 1.37E-06 9863200 1346 946.6 934.49 1253.7 1466.4 1439.5 1371.4 794.45 1169.5 1117.3 TRUE FALSE FALSE 1239.46268 1028.419886 969.1230215 1248.512522 1448.914138 1140.931473 1409.877793 1036.674148 1041.208776 1156.126092 1.072082611 0.889539552 0.838250281 1.079910341 1.253249233 0.9868573 1.219484452 0.896679138 0.900601399 1 10.17508304 -6.0224068 24.68086097 1.006272972 1.100519496 0.175419512 0.122206414 1022.874031 1126684.991 0.017396099 0.029005668 9.50E-07 6.0224068 0.094246524 QVAPEK(ac)PVK ddPTM_HeLa_Curcumin_4h_R1 2 QVAPEKPVK 9 1 P53999;D6RC37;D6R970 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 0 1 ; QVAPEK(1)PVK;QVAPEK(1)PVK 102.06 0.0073828 24773000 11935.3 11829.6 12325.8 11618.8 15907.5 15257 14203.4 14636.4 12058.5 9399.9 FALSE TRUE FALSE 10990.60841 12852.09791 12782.60499 11570.72448 15717.81345 12092.52622 14601.90918 19098.97098 10735.71272 9726.545825 1.129960071 1.321342452 1.314197786 1.189602629 1.61597074 1.243249807 1.501243035 1.963592351 1.103753883 1 13.24771184 -1 0.216207704 0.988061905 5.240054854 0.715140811 0.14514101 17.32762469 0.205829261 0.106311076 25.80217596 0.1 1 4.251992949 QVAQQEAER ddPTM_HeLa_Curcumin_4h_R1 1 QVAQQEAER 9 0 P35232;C9JZ20;E7ESE2;E9PCW0;C9JW96 P35232 PHB Prohibitin 0 0 98.033 0.011867 607890 519.18 204.86 310.66 350.47 356.81 437.38 310.02 339.22 405.31 353.76 FALSE FALSE TRUE 478.0863552 222.5671856 322.1733329 349.019848 352.5552738 346.6624577 318.7183268 442.6466164 360.848507 366.0531337 1.306057267 0.608018796 0.880127236 0.953467723 0.963125955 0.947027701 0.870688699 1.209241434 0.985781773 1 8.515909265 -7.289434196 24.99057193 1.144527031 0.919597221 0.187439607 0.161523823 701.245345 625989.7981 0.029286577 0.033493992 5.14E-08 7.289434196 -0.22492981 QVCPDLLRK ddPTM_HeLa_Curcumin_4h_R1 1 QVCPDLLRK 9 1 Q8IYW2 Q8IYW2 CFAP46 Cilia- and flagella-associated protein 46 0 0 106.68 0.007343 48390000 4538.7 4733.9 2628.5 3286.6 4348.3 9719.1 3906 3528.7 5472.2 3621.3 FALSE FALSE TRUE 4179.457106 5143.077222 2725.914522 3273.00092 4296.449362 7703.249103 4015.591848 4604.584386 4871.913351 3747.139905 1.11537258 1.37253408 0.727465371 0.873466431 1.146594328 2.055767678 1.071641825 1.228826385 1.300168522 1 11.87157413 -5.504367436 24.69010905 1.042343263 1.445225962 0.255739076 0.294864141 597.9594885 797548.5067 0.038830916 0.085377501 3.13E-06 5.504367436 0.402882699 QVDLES(ph)NPQNRSPESRPSVVYPSTK ddPTM_HeLa_Curcumin_4h_R1 1 QVDLESNPQNRSPESRPSVVYPSTK 25 2 J3QS41;P42694 J3QS41 HELZ Probable helicase with zinc finger domain 1 0 QVDLES(0.632)NPQNRS(0.366)PES(0.001)RPS(0.001)VVYPSTK 63.979 0.001749 14453000 787.07 624.43 533.57 604.59 638.35 876.01 538.21 452.05 784.67 511.98 TRUE FALSE FALSE 724.772579 678.4029468 553.3445736 602.0883668 630.7380932 694.3156513 553.3107241 589.877964 698.5936641 529.7712669 1.368085859 1.280558213 1.044497141 1.136506271 1.190585697 1.310595147 1.044433246 1.113457828 1.318670354 1 9.049225788 -6.76757562 24.99198874 1.186680487 1.145561201 0.079634863 0.120336494 724.4926331 2950742.405 0.025500603 0.03400071 1.71E-07 6.76757562 -0.041119287 QVDLESNPQNRS(ph)PESRPSVVYPSTK ddPTM_HeLa_Curcumin_4h_R1 1 QVDLESNPQNRSPESRPSVVYPSTK 25 2 J3QS41;P42694 J3QS41 HELZ Probable helicase with zinc finger domain 1 0 QVDLES(0.029)NPQNRS(0.936)PES(0.023)RPS(0.007)VVY(0.004)PS(0.001)TK 64.845 0.001347 20783000 974.55 791.46 896.57 970.29 1005.2 1020 709.14 581.13 817.05 1094.3 TRUE FALSE FALSE 897.4133392 859.8702757 929.7976729 966.2751971 993.2136465 808.4405022 729.0365598 758.3138618 727.4216592 1132.326844 0.792539137 0.759383459 0.821138948 0.853353608 0.877143956 0.713963911 0.643839333 0.669695209 0.642413154 1 10.14507473 -13.52287875 0.076409921 1.817338489 0.490125656 0 0.122708154 86.29987387 0.508401054 12.27872749 1.493585695 3.00E-14 13.52287875 -1.327212832 QVDQLTNDK ddPTM_HeLa_Curcumin_4h_R1 1 QVDQLTNDK 9 0 P08670;B0YJC4 P08670 VIM Vimentin 0 0 160.75 2.39E-08 18712000 6715 5760 6199.7 6185.6 6679.7 7747.1 5865.4 5853.3 6253.6 5830.5 FALSE FALSE TRUE 6183.500664 6257.868734 6429.466336 6160.005626 6600.04894 6140.264132 6029.967338 7637.944225 5567.595726 6033.109441 1.024927647 1.037254304 1.065696951 1.021033297 1.09397136 1.017761105 0.99947919 1.266004587 0.922840167 1 12.55868604 -4.258038968 24.99612254 1.02316672 1.266004678 0.748572617 0.042685673 90.15443018 662686.4147 0.004272409 0.041402923 5.52E-05 4.258038968 0.242837958 QVDQLTNDK(ac)AR ddPTM_HeLa_Curcumin_4h_R1 2 QVDQLTNDKAR 11 1 P08670;B0YJC4 P08670 VIM Vimentin 0 1 ; QVDQLTNDK(1)AR;QVDQLTNDK(1)AR 236.69 5.91E-41 7525700 2533.7 2328.61 1436.28 1756.26 2068.88 3419.6 2538.4 2767 4770 2568 FALSE TRUE FALSE 2333.154971 2529.884672 1489.5098 1748.993061 2044.209957 2710.336413 2609.620672 3610.645562 4246.742934 2657.237809 0.878037699 0.952073113 0.560548173 0.658199675 0.769298837 1.019982632 0.982080213 1.358796548 1.598179478 1 11.37571163 -4.050714383 1.490752465 0.884369761 1.753736499 0.175244975 0.26673489 1.449246324 1.969589849 0.023814815 2.148000502 8.90E-05 4.050714383 0.869366738 QVEDEKNSFR ddPTM_HeLa_Curcumin_4h_R1 1 QVEDEKNSFR 10 1 P35579 P35579 MYH9 Myosin-9 0 0 86.882 0.013411 1910700 1990.8 1506.8 1532.9 1844.2 1628.6 1918.5 1409 1366.3 1633.3 2115.9 FALSE FALSE TRUE 1833.226079 1637.041078 1589.710622 1836.569189 1609.180009 1520.581474 1448.532748 1782.87858 1454.131076 2189.427368 0.83730847 0.747702848 0.726085115 0.838835403 0.734977571 0.694511038 0.661603472 0.814312732 0.664160455 1 11.09633787 -8.277837665 0.416003497 1.024115455 0.718833272 0 0.115388387 0.378830126 0.148231718 0.048760684 0.021457018 5.27E-09 8.277837665 -0.305282184 QVEEEILALK ddPTM_HeLa_Curcumin_4h_R1 1 QVEEEILALK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 114.89 0.0038847 496130 275.74 151.8 207.58 280.18 173.75 254.9 213.42 203.2 331.59 221.38 FALSE FALSE TRUE 253.914888 164.9209156 215.2730974 279.0206894 171.6781447 202.0308667 219.4079908 265.1547446 295.2154066 229.0729385 1.108445588 0.71994936 0.939757873 1.218043001 0.749447516 0.88194995 0.957808427 1.157512303 1.288739772 1 7.839663226 QVEPPAK ddPTM_HeLa_Curcumin_4h_R1 1 QVEPPAK 7 0 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;P29692-4;E9PQZ1;E9PL12;E9PPR1;H0YE72;E9PK06 P29692 EEF1D Elongation factor 1-delta 0 0 107.59 0.015477 3249100 4079.5 3612.7 3425.2 2983.1 3640.5 4283.3 3069.9 3221.5 3088.3 3288 FALSE FALSE TRUE 3756.60327 3924.96569 3552.140925 2970.756723 3597.089415 3394.895297 3156.033132 4203.72052 2749.521217 3402.257755 1.104150109 1.153635607 1.044054031 0.873172151 1.057265403 0.997836008 0.927629051 1.235567915 0.808146065 1 11.73227673 -6.509327911 24.87013161 1.06031663 1.008718416 0 0.125196686 1485.273797 2725953.801 0.01489003 0.022128552 3.10E-07 6.509327911 -0.051598214 QVEPPAKKPATPAEDDEDDDIDLFGS(ph)DNEEEDKEAAQLR ddPTM_HeLa_Curcumin_4h_R1 3 QVEPPAKKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLR 39 3 P29692;E9PK01;E9PI39;E9PQ49;P29692-2;E9PL71;P29692-3;E9PRY8;A0A087X1X7;P29692-4;E9PQZ1;H0YE72 P29692 EEF1D Elongation factor 1-delta 1 0 QVEPPAKKPAT(0.005)PAEDDEDDDIDLFGS(0.995)DNEEEDKEAAQLR;QVEPPAKKPAT(0.003)PAEDDEDDDIDLFGS(0.997)DNEEEDKEAAQLR;QVEPPAKKPAT(0.015)PAEDDEDDDIDLFGS(0.985)DNEEEDKEAAQLR ;; 59.093 6.88E-05 302266000 5728 4243.1 4567.1 5070.6 3940.3 5927 4623.4 5449.1 6515.9 5634.1 TRUE FALSE FALSE 5274.622756 4609.854657 4736.360744 5049.619201 3893.314496 4697.673389 4753.120161 7110.505505 5801.122072 5829.884556 0.904755953 0.790728292 0.812427879 0.866161097 0.66782017 0.805791838 0.815302621 1.21966489 0.995066372 1 12.5092516 -8.077346009 1.032278709 0.981387882 0.844093709 0.136352967 0.13481994 0.604218744 1.357001699 0.036891168 0.028287833 8.37E-09 8.077346009 -0.137294172 QVETEEAGVVTT(ph)ATASVNLKVSPK ddPTM_HeLa_Curcumin_4h_R1 1 QVETEEAGVVTTATASVNLKVSPK 24 1 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 1 0 QVETEEAGVVT(0.035)T(0.593)AT(0.024)AS(0.204)VNLKVS(0.145)PK 96.505 2.30E-05 89796000 4644.6 4964.8 3899.7 4630.4 4847.7 4738.8 4610.6 3853.9 5924.3 4866 TRUE FALSE FALSE 4276.975009 5393.935189 4044.226313 4611.240632 4789.894344 3755.919463 4739.961027 5028.936369 5274.419112 5035.093138 0.849433147 1.071268205 0.803207846 0.915820325 0.951302034 0.745948359 0.941384975 0.998777228 1.047531588 1 12.29780275 -9.559501046 1.284372728 1.000878689 0.901152682 0.185400913 0.090510448 0.707262075 2.060377364 0.062479208 0.014179034 2.76E-10 9.559501046 -0.099726007 QVETEEAGVVTTATASVNLKVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 13 QVETEEAGVVTTATASVNLKVSPK 24 1 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 1 0 QVETEEAGVVT(0.107)T(0.107)AT(0.013)AS(0.365)VNLKVS(0.409)PK;QVETEEAGVVT(0.015)T(0.015)AT(0.008)AS(0.023)VNLKVS(0.939)PK;QVET(0.001)EEAGVVT(0.159)T(0.125)AT(0.085)AS(0.06)VNLKVS(0.57)PK;QVETEEAGVVT(0.165)T(0.127)AT(0.024)AS(0.068)VNLKVS(0.617)PK;QVETEEAGVVTTATAS(0.047)VNLKVS(0.952)PK;QVETEEAGVVT(0.004)T(0.01)AT(0.002)AS(0.007)VNLKVS(0.977)PK;QVETEEAGVVT(0.036)T(0.113)AT(0.085)AS(0.009)VNLKVS(0.756)PK;QVETEEAGVVT(0.003)T(0.002)AT(0.037)AS(0.007)VNLKVS(0.95)PK;QVETEEAGVVT(0.006)T(0.006)AT(0.006)AS(0.015)VNLKVS(0.968)PK;QVETEEAGVVTTATAS(0.005)VNLKVS(0.995)PK;QVETEEAGVVT(0.03)T(0.023)AT(0.072)AS(0.158)VNLKVS(0.717)PK;QVETEEAGVVTTATAS(0.01)VNLKVS(0.99)PK;QVETEEAGVVTT(0.001)AT(0.001)AS(0.019)VNLKVS(0.98)PK ;;;;;;;;;;;; 151.35 1.18E-07 485885300 15915.52 14582.27 13467.19 16996.21 14783.93 16961.05 14875.12 12532.79 18526.2 16133.5 TRUE FALSE FALSE 14655.7898 15842.69644 13966.29591 16925.88419 14607.64129 13443.13704 15292.47583 16353.97998 16493.92221 16694.13792 0.877900366 0.948997577 0.836598809 1.013881895 0.87501621 0.805260931 0.916038666 0.979624108 0.988006825 1 14.02705397 -9.387625102 0.968404476 1.003499663 0.903013645 0.250877203 0.059962577 0.644968683 1.020074486 0.047470969 0.010589424 4.10E-10 9.387625102 -0.100486017 QVHPDTGIS(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 QVHPDTGISSK 11 0 P33778;P58876;P62807;P57053;O60814;Q16778;P06899;Q5QNW6;Q5QNW6-2;Q8N257;Q93079;U3KQK0;Q99877;Q99879;Q99880 P33778;P58876;P62807;Q16778;Q5QNW6;Q8N257;Q93079;U3KQK0;Q99879;Q99880 HIST1H2BB;HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST2H2BF;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BM;HIST1H2BL Histone H2B type 1-B;Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 2-F;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-M;Histone H2B type 1-L 1 0 QVHPDT(0.012)GIS(0.494)S(0.494)K 182.72 0.00012069 55519000 8185.5 6912.5 7013.6 7912.7 8058.2 9711.1 7669 4787.6 9316.3 7166.7 TRUE FALSE FALSE 7537.609038 7509.985698 7273.530186 7879.959344 7962.111228 7696.908393 7884.1715 6247.317201 8294.325198 7415.742292 1.01643352 1.01270856 0.980822944 1.062598865 1.073676904 1.037914762 1.063166867 0.842439901 1.118475383 1 12.85637539 -4.252614133 24.95381577 1.019269868 0.842439808 0.623657418 0.043421691 461.6061556 1305185.419 0.004541346 0.073176356 5.59E-05 4.252614133 -0.17683006 QVHPDTGISS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 QVHPDTGISSK 11 0 P33778;P58876;P62807;P57053;O60814;Q16778;P06899;Q5QNW6;Q5QNW6-2;Q8N257;Q93079;U3KQK0;Q99877;Q99879;Q99880 P33778;P58876;P62807;Q16778;Q5QNW6;Q8N257;Q93079;U3KQK0;Q99879;Q99880 HIST1H2BB;HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST2H2BF;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BM;HIST1H2BL Histone H2B type 1-B;Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 2-F;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-M;Histone H2B type 1-L 1 0 QVHPDTGIS(0.173)S(0.827)K 135.02 0.00098874 32221000 12759 10521 10552 11518 11252 14181 10915 13169 13486 10434 TRUE FALSE FALSE 11749.11169 11430.38836 10943.0664 11470.34157 11117.82725 11239.70075 11221.24552 17184.16748 12006.61954 10796.58072 1.088225244 1.058704478 1.013567784 1.062405021 1.029754469 1.041042626 1.039333268 1.591630528 1.112076114 1 13.39828686 -4.261262182 24.97198815 1.042132523 1.591630692 0.961914628 0.032335094 1.82045558 256342.7496 0.004576986 0.035399748 5.48E-05 4.261262182 0.549498169 QVHPDTGISSK ddPTM_HeLa_Curcumin_4h_R1 5 QVHPDTGISSK 11 0 P33778;P58876;P62807;P57053;O60814;Q16778;P06899;Q5QNW6;Q5QNW6-2;Q8N257;Q93079;U3KQK0;Q99877;Q99879;Q99880 P33778;P58876;P62807;Q16778;Q5QNW6;Q8N257;Q93079;U3KQK0;Q99879;Q99880 HIST1H2BB;HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST2H2BF;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BM;HIST1H2BL Histone H2B type 1-B;Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 2-F;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-M;Histone H2B type 1-L 0 0 ;;;; ;;;; 118.61 0.0013836 240305000 55187.8 46075.4 43370.2 40604.3 58822.5 78190 53217.9 45367.6 56584.2 44375.2 FALSE FALSE TRUE 50819.6274 50057.95227 44977.53776 40436.29017 58121.08011 61972.51262 54711.05105 59199.97239 50377.05483 45917.2349 1.106765848 1.090177847 0.97953498 0.88063426 1.265779184 1.349656894 1.191514497 1.28927564 1.097127363 1 15.48674815 -5.689298869 10.79480898 1.038422978 1.274114848 0.73344274 0.073109873 0.206428612 29.75713799 0.011245949 0.022496294 2.05E-06 5.689298869 0.23569187 QVLLGDQIPK ddPTM_HeLa_Curcumin_4h_R1 2 QVLLGDQIPK 10 0 P28072 P28072 PSMB6 Proteasome subunit beta type-6 0 0 ; ; 133.23 0.0010143 4327500 4363 3154.7 4148.5 3355.7 3693.8 6125.8 4780.8 4418.1 4413.7 4137 FALSE FALSE TRUE 4017.663946 3427.378211 4302.247059 3341.815003 3649.753847 4855.240028 4914.936381 5765.158352 3929.528153 4280.760442 0.938539776 0.800647048 1.005019346 0.780659195 0.852594743 1.134200358 1.148145627 1.346760331 0.917950959 1 12.06365139 -4.764309812 1.730654378 0.939847137 1.316741129 0.717364361 0.088918968 0.200335203 1.040000897 0.013557881 0.090454 1.72E-05 4.764309812 0.376893992 GWS(ph)QEGPVK ddPTM_HeLa_Curcumin_4h_R1 2 GWSQEGPVK 9 0 Q9C0C2;E9PKK0 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 GWS(1)QEGPVK;GWS(1)QEGPVK ; 100.09 0.01308 59598000 3823 2936.1 4133.7 5096.5 4171.8 6649.5 8527.1 32769 0 3506.5 TRUE FALSE FALSE 3520.405516 3189.883401 4286.898558 5075.412033 4122.05401 5270.318745 8766.347476 42760.11725 0 3628.350614 0.97024954 0.879155225 1.181500636 1.398820724 1.136068271 1.452538441 2.416069561 11.78500145 0 1 11.82509816 -4.236453537 2.893187294 1.062365033 14.0298337 0.985620451 0.388236725 0.022409592 0.249465892 0.033684302 0.69550751 5.80E-05 4.236453537 12.96746866 up QVLTAPGS(ph)AGQPRSEDEDS(ph)LEEAGSPAPGPCPR ddPTM_HeLa_Curcumin_4h_R1 2 QVLTAPGSAGQPRSEDEDSLEEAGSPAPGPCPR 33 1 Q8TBB5-2;Q8TBB5-3;Q8TBB5 Q8TBB5-2 KLHDC4 Kelch domain-containing protein 4 2 0 QVLT(0.01)APGS(0.97)AGQPRS(0.02)EDEDS(0.997)LEEAGS(0.002)PAPGPCPR;QVLT(0.04)APGS(0.903)AGQPRS(0.081)EDEDS(0.948)LEEAGS(0.028)PAPGPCPR ; 86.076 5.57E-08 43564000 3559.6 2552.1 3162.7 3797.1 3144.3 3703.9 2584.8 2204.47 3497.1 3027.1 TRUE FALSE FALSE 3277.853904 2772.692152 3279.912444 3781.388606 3106.806276 2935.669388 2657.322531 2876.602755 3113.476879 3132.2915 1.046471538 0.885196078 1.047128738 1.207227554 0.991863713 0.93722739 0.84836374 0.918370067 0.993993337 1 11.61300276 -5.173222516 3.053783679 1.026712217 0.886076872 0.364827355 0.076717939 0.211157645 3.792388986 0.01102797 0.031589239 6.71E-06 5.173222516 -0.140635345 QVLTAPGSAGQPRS(ph)EDEDS(ph)LEEAGSPAPGPCPR ddPTM_HeLa_Curcumin_4h_R1 1 QVLTAPGSAGQPRSEDEDSLEEAGSPAPGPCPR 33 1 Q8TBB5-2;Q8TBB5-3;Q8TBB5 Q8TBB5-2 KLHDC4 Kelch domain-containing protein 4 2 0 QVLT(0.03)APGS(0.378)AGQPRS(0.795)EDEDS(0.792)LEEAGS(0.006)PAPGPCPR 64.592 0.00015304 29847000 1600.1 1210.2 1290.1 1120.3 1273.8 1385.4 1452.4 706 1491.7 1247.4 TRUE FALSE FALSE 1473.450397 1314.804295 1337.912241 1115.664495 1258.610767 1098.052423 1493.150435 921.25615 1328.064242 1290.747057 1.141548523 1.018638228 1.036540997 0.864355638 0.975102566 0.85071077 1.156811032 0.713738718 1.028911307 1 10.33399059 -6.416128146 4.854924664 1.06366531 0.926115408 0.253786336 0.111241208 0.234286238 8.650688934 0.016495054 0.025332474 3.84E-07 6.416128146 -0.137549902 QVLTAPGSAGQPRS(ph)EDEDSLEEAGSPAPGPCPR ddPTM_HeLa_Curcumin_4h_R1 1 QVLTAPGSAGQPRSEDEDSLEEAGSPAPGPCPR 33 1 Q8TBB5-2;Q8TBB5-3;Q8TBB5 Q8TBB5-2 KLHDC4 Kelch domain-containing protein 4 1 0 QVLT(0.009)APGS(0.206)AGQPRS(0.724)EDEDS(0.061)LEEAGSPAPGPCPR 71.864 7.95E-06 24704000 464.55 409.94 413.03 520.63 439.32 418.1 343.09 185.47 300.9 398.85 TRUE FALSE FALSE 427.7803773 445.3733869 428.3372551 518.475771 434.0813959 331.381347 352.716182 242.0189492 267.8920228 412.7100078 1.036515639 1.079143657 1.037864959 1.25627138 1.051783062 0.802939935 0.854634429 0.586414055 0.649104741 1 8.688984612 -4.661542326 1.311224094 1.042311213 0.582572058 0.401716017 0.15272958 0.307596011 0.72519748 0.013772909 0.155016955 2.18E-05 4.661542326 -0.459739156 QVNTISEAIVAEEDEEGRLDR ddPTM_HeLa_Curcumin_4h_R1 1 QVNTISEAIVAEEDEEGRLDR 21 1 J3QQQ3;Q96NB3 J3QQQ3 ZNF830 Zinc finger protein 830 0 0 85.61 0.00069195 1776200 1010.2 736.39 870.34 957.16 1065.2 1430 1091.7 725.44 986.85 876.54 FALSE FALSE TRUE 930.241604 800.0402703 902.595566 953.1995255 1052.498186 1133.401881 1122.330164 946.6233165 878.595024 906.9996998 1.025625041 0.882073357 0.995144283 1.05093698 1.160417347 1.2496166 1.237409631 1.043686472 0.968682817 1 9.824958263 -5.828363389 2.914038637 1.000005222 1.186173351 0.663228528 0.065354121 0.122972948 2.120584086 0.0096119 0.019097322 1.48E-06 5.828363389 0.186168129 QVPGGGGGGGSGGGGGSGGGGS(ph)GGGR ddPTM_HeLa_Curcumin_4h_R1 2 QVPGGGGGGGSGGGGGSGGGGSGGGR 26 0 K7EN53;K7EQC2;Q9UHB9-4;Q9UHB9-2;Q9UHB9 K7EN53 SRP68 Signal recognition particle subunit SRP68 1 0 QVPGGGGGGGS(0.01)GGGGGS(0.28)GGGGS(0.71)GGGR;QVPGGGGGGGSGGGGGS(0.061)GGGGS(0.939)GGGR ; 99.097 4.18E-06 7004800 2636.5 2272.3 1859.74 2134.1 1853.73 1952.01 1829.27 1363.25 2364.9 2668.1 TRUE FALSE FALSE 2427.818243 2468.707487 1928.6636 2125.26966 1831.62548 1547.141122 1880.594393 1778.898649 2105.476387 2760.816276 0.879384211 0.894194774 0.698584552 0.76979757 0.663436208 0.56039264 0.681173321 0.644337932 0.762628214 1 11.43087917 -6.750671906 0.518914373 0.979194099 0.607634749 0.569010942 0.083631286 0.20138405 0.116901265 0.015956182 0.029233861 1.78E-07 6.750671906 -0.37155935 QVPT(ph)T(ph)EAELLVSGDENCAY(ph)FEVSAK ddPTM_HeLa_Curcumin_4h_R1 1 QVPTTEAELLVSGDENCAYFEVSAK 25 0 Q96D21 Q96D21 RASD2 GTP-binding protein Rhes 3 0 QVPT(0.857)T(0.857)EAELLVS(0.287)GDENCAY(0.801)FEVS(0.199)AK 53.779 0.0049074 0 245.59 346.8 321.01 311.92 305.08 132.36 208.69 225.02 160.97 211.65 TRUE FALSE FALSE 226.1512924 376.7758467 332.906913 310.6293577 301.4421203 104.907044 214.5452797 293.6275621 143.3119937 219.0048217 1.032631567 1.720399778 1.520089422 1.418367665 1.376417733 0.479017052 0.979637243 1.340735605 0.654378258 1 7.774818823 -3.266262805 14.53210253 1.118520166 1.028274186 0 0.373419416 0 0 0.047943872 0 0.000541673 3.266262805 -0.09024598 QVQQNS(ph)LHR ddPTM_HeLa_Curcumin_4h_R1 2 QVQQNSLHR 9 0 Q15811;Q15811-3;F8W7U0;Q15811-7;Q15811-8;Q15811-9;Q15811-2;Q15811-4;Q15811-10;Q15811-11;Q15811-12;Q15811-6;Q15811-5;Q15811-13;A8CTZ0;CON__ENSEMBL:ENSBTAP00000001528 Q15811 ITSN1 Intersectin-1 1 0 QVQQNS(1)LHR;QVQQNS(1)LHR ; 116.84 0.0033331 17026500 2100.4 1673.61 2150.1 1708.86 2399.4 2459.7 2294.11 2905.1 1960.36 2291 TRUE FALSE FALSE 1934.151124 1818.269391 2229.784597 1701.78919 2370.788722 1949.530493 2358.476552 3790.851617 1745.313413 2370.612079 0.815886808 0.767004187 0.940594464 0.717869113 1.000074514 0.822374319 0.994880846 1.599102464 0.736229022 1 11.21104389 -4.267476908 3.338725346 0.890350681 1.689146192 0.821926907 0.102904805 0.09443575 1.727790146 0.013898533 0.191120322 5.40E-05 4.267476908 0.798795511 QVQSLTCEVDALK ddPTM_HeLa_Curcumin_4h_R1 1 QVQSLTCEVDALK 13 0 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 0 270.02 1.24E-77 1680500 707.54 494.12 420.54 523.07 529.25 689.66 625.7 491.45 438.48 650.39 FALSE FALSE TRUE 651.5374624 536.829531 436.1255823 520.9056749 522.9390394 546.6167419 643.255458 641.2908426 390.379841 672.9910041 0.968122097 0.797677128 0.648040731 0.774015807 0.777037191 0.812219983 0.955815834 0.952896604 0.580066953 1 9.39444341 -7.297699844 5.627232719 0.985578649 0.812213395 0 0.153334439 0.136142472 12.1836556 0.015800379 0.018218069 5.04E-08 7.297699844 -0.173365254 QVQSLTCEVDALKGTNESLER ddPTM_HeLa_Curcumin_4h_R1 1 QVQSLTCEVDALKGTNESLER 21 1 P08670;B0YJC4;B0YJC5 P08670 VIM Vimentin 0 0 138.28 3.36E-05 788500 355.83 305.07 275.04 242.17 208.6 327.28 97.164 210.16 337.38 196.45 FALSE FALSE TRUE 327.66568 331.4388914 285.2332243 241.1679647 206.1125812 259.3984388 99.89016034 274.2368165 300.3702581 203.2766229 1.611920128 1.630482083 1.403177701 1.18640285 1.013951227 1.276085932 0.491400137 1.349081919 1.477642898 1 7.667300502 -5.926076482 2.774882276 1.334722236 1.007021677 0.283892454 0.275371844 0.361489677 5.646330476 0.048653745 0.093485924 1.19E-06 5.926076482 -0.327700559 QVS(ph)ASELHTSGILGPETLR ddPTM_HeLa_Curcumin_4h_R1 7 QVSASELHTSGILGPETLR 19 0 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 1 0 QVS(0.96)AS(0.005)ELHT(0.032)S(0.003)GILGPETLR;QVS(0.891)AS(0.107)ELHT(0.002)SGILGPETLR;QVS(0.859)AS(0.141)ELHTSGILGPETLR;QVS(0.761)AS(0.187)ELHT(0.051)S(0.001)GILGPETLR;QVS(0.43)AS(0.271)ELHT(0.298)S(0.001)GILGPETLR;QVS(0.481)AS(0.289)ELHT(0.152)S(0.078)GILGPETLR;QVS(0.82)AS(0.064)ELHT(0.115)S(0.001)GILGPETLR ;;;;;; 261.94 5.04E-55 386690000 11922.82 9624.02 10239.48 10250.23 11607.17 23694.58 15987.48 10755.83 13427.93 10816.34 TRUE FALSE FALSE 10979.11622 10455.8774 10618.96414 10207.81726 11468.76208 18780.05702 16436.04566 14035.23305 11954.91967 11192.20701 0.980960789 0.934210509 0.948781963 0.91204686 1.02470961 1.677958333 1.468525881 1.254018358 1.068146762 1 13.45020693 -5.345986182 6.798071273 0.977834497 1.465611895 0.822749685 0.103370556 0.065445023 4.462010388 0.013584874 0.030606135 4.51E-06 5.345986182 0.487777397 QVS(ph)SEGSPGVR ddPTM_HeLa_Curcumin_4h_R1 1 QVSSEGSPGVR 11 0 K7ESA6 K7ESA6 GCDH 1 0 QVS(0.742)S(0.033)EGS(0.226)PGVR 89.356 0.018138 46831000 2996.7 2657.5 3300.5 3375.9 3045.3 1421.8 1130.5 1121.9 2980.9 2561.1 TRUE FALSE FALSE 2759.508033 2887.202458 3422.819433 3361.93142 3008.986786 1126.902653 1162.218787 1463.962145 2653.902728 2650.098034 1.041285265 1.089470058 1.291582194 1.268606435 1.135424708 0.425230553 0.438556903 0.552418109 1.00143568 1 11.37183001 -5.260295338 24.99982036 1.072077767 0.468717327 0.88494453 0.105859026 29.58840908 646560.355 0.017949039 0.043095269 5.49E-06 5.260295338 -0.60336044 QVSS(ph)PSFTNR ddPTM_HeLa_Curcumin_4h_R1 2 QVSSPSFTNR 10 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 QVS(0.076)S(0.895)PS(0.029)FTNR;QVS(0.087)S(0.911)PS(0.002)FTNR ; 158.34 0.00062429 61989000 7926 7407 7141.3 6928.9 6529.4 8692 8702.3 3101.9 7918.7 6153.9 TRUE FALSE FALSE 7298.648737 8047.228075 7405.96286 6900.230048 6451.541169 6889.181221 8946.463117 4047.655031 7050.038422 6367.747567 1.146190024 1.263747972 1.163042784 1.083621795 1.013159065 1.081886672 1.404965103 0.635649417 1.107147912 1 12.63656743 -4.234145312 24.17959003 1.104469143 0.635648392 0.606821941 0.118761184 3578.403939 3170002.806 0.017124098 1.953281135 5.83E-05 4.234145312 -0.468820751 QVSS(ph)VNEEDFVR ddPTM_HeLa_Curcumin_4h_R1 1 QVSSVNEEDFVR 12 0 P40189-3;P40189 P40189-3 IL6ST Interleukin-6 receptor subunit beta 1 0 QVS(0.013)S(0.987)VNEEDFVR 110.55 0.0054167 2230700 1555.1 1354.8 1781.9 1786.8 1667 1468.2 1324.8 1081.3 1898.1 1674.5 TRUE FALSE FALSE 1432.012194 1471.902875 1847.938782 1779.406695 1647.122114 1163.67877 1361.970322 1410.983392 1689.883179 1732.68875 0.826468224 0.84949064 1.066515138 1.026962687 0.950616268 0.671602889 0.786044419 0.81433171 0.975295291 1 10.75879681 -5.276734629 24.71782023 0.93269521 0.760198147 0.556839725 0.079444805 501.8980976 811089.9952 0.013766719 0.030895545 5.29E-06 5.276734629 -0.172497063 QVTDAETKPK ddPTM_HeLa_Curcumin_4h_R1 1 QVTDAETKPK 10 1 O43684-2;O43684 O43684-2 BUB3 Mitotic checkpoint protein BUB3 0 0 83.869 0.016082 1948600 894.32 959.37 839.22 839.11 581.14 1485.4 1059.7 701.64 868.84 807.18 FALSE FALSE TRUE 823.5336283 1042.293668 870.3222315 835.6379852 574.2102851 1177.311296 1089.43233 915.566806 773.5304257 835.2294449 0.985996882 1.247912983 1.042015744 1.000489135 0.687488077 1.409566321 1.304350962 1.096185978 0.926129258 1 9.706028763 -5.234986605 24.99881915 0.999463041 1.273466068 0.438634827 0.147422014 541.0970892 511355.3791 0.019778258 0.050408171 5.82E-06 5.234986605 0.274003027 QVTMAEAS(ph)EDSPR ddPTM_HeLa_Curcumin_4h_R1 1 QVTMAEASEDSPR 13 0 F5H1D6;Q07864 F5H1D6 POLE DNA polymerase;DNA polymerase epsilon catalytic subunit A 1 0 QVTMAEAS(1)EDSPR 94.692 0.0097641 3078700 1950.9 2500.3 3403.6 2528.3 2224 2590.4 2842.5 2025.6 3118.4 3863.2 TRUE FALSE FALSE 1796.484206 2716.414791 3529.74041 2517.838565 2197.480253 2053.12184 2922.2529 2643.196115 2776.319322 3997.445912 0.449408008 0.679537597 0.882998917 0.629861822 0.549721072 0.51360841 0.731030004 0.661221233 0.694523299 1 11.9648628 -9.506932583 1.238859778 1.001309775 0.620934247 0.129996469 0.146625724 0.284628581 0.777584627 0.092063029 0.02193774 3.11E-10 9.506932583 -0.380375528 QVVES(ph)AYEVIK ddPTM_HeLa_Curcumin_4h_R1 2 QVVESAYEVIK 11 0 P00338;P00338-3;P00338-4 P00338 LDHA L-lactate dehydrogenase A chain 1 0 QVVES(1)AYEVIK;QVVES(1)AYEVIK ; 167.32 0.00025734 10570900 4232.9 3736.4 3501.9 3531.2 3970 4069.2 3407.9 2616.2 3617.6 3508.7 TRUE FALSE FALSE 3897.861498 4059.357767 3631.683495 3516.58883 3922.660343 3225.202051 3503.516502 3413.867336 3220.758331 3630.627064 1.073605587 1.118087233 1.000290977 0.968589935 1.080436044 0.888331959 0.964989364 0.94029689 0.887108005 1 11.82600303 -5.262331958 24.99999769 1.036809255 0.9345844 0.240138481 0.065354885 51.87442981 1452970.704 0.007001206 0.016552993 5.47E-06 5.262331958 -0.102224856 QVVESAYEVIK ddPTM_HeLa_Curcumin_4h_R1 2 QVVESAYEVIK 11 0 P00338;P00338-3;P00338-4 P00338 LDHA L-lactate dehydrogenase A chain 0 0 ; ; 192.3 3.54E-16 21271200 7533.4 6662.3 6519.4 6689.7 6972.4 8357.5 6434.7 6368.2 7252.1 7016.1 FALSE FALSE TRUE 6937.123441 7238.159525 6761.014699 6662.019794 6889.258684 6624.060292 6615.240364 8309.834864 6456.562774 7259.908953 0.955538628 0.997004174 0.931280921 0.917645089 0.948945604 0.912416441 0.91120156 1.144619708 0.889344869 1 12.82573574 -9.229060912 0.713295015 1.003387117 0.958396662 0 0.074113028 2.301711623 1.854780668 0.062434468 0.012980452 5.90E-10 9.229060912 -0.044990455 QVVSVVQDEEVGLPFEASPES(ph)PPPASPDGVTEIR ddPTM_HeLa_Curcumin_4h_R1 2 QVVSVVQDEEVGLPFEASPESPPPASPDGVTEIR 34 0 Q96TA1-2;Q96TA1 Q96TA1-2 FAM129B Niban-like protein 1 1 0 QVVSVVQDEEVGLPFEAS(0.005)PES(0.994)PPPAS(0.001)PDGVTEIR;QVVSVVQDEEVGLPFEAS(0.147)PES(0.853)PPPASPDGVTEIR ; 127.95 3.33E-18 6536800 5553.5 5077.9 5034.4 5108.2 5019.2 5534.7 5258.6 5085 6108.3 5340.7 TRUE FALSE FALSE 5113.934615 5516.811049 5220.979293 5087.063622 4959.349318 4386.740831 5406.142163 6635.393092 5438.234772 5526.288927 0.925383143 0.998284947 0.944753226 0.920520749 0.897410429 0.793795056 0.978259051 1.200696015 0.984066314 1 12.43209528 -4.278154874 4.651027066 0.946140689 1.213019306 0.647155462 0.058278575 0.090994231 5.130812986 0.008791651 0.076020681 5.27E-05 4.278154874 0.266878617 ENDPLRT(ph)PEALPEEK ddPTM_HeLa_Curcumin_4h_R1 1 ENDPLRTPEALPEEK 15 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 0 ENDPLRT(1)PEALPEEK 127.91 0.00062347 41272000 2858 2186 2090.2 2227.9 2461.1 3083.2 3846.3 6186.1 2359.6 2079.1 TRUE FALSE FALSE 2631.786284 2374.948099 2167.664651 2218.68154 2431.75299 2443.709565 3954.216826 8072.213413 2100.757783 2151.34857 1.223319327 1.103934589 1.007584118 1.031298029 1.130338906 1.135896618 1.838017735 3.752164351 0.976484152 1 11.07102558 -4.23589871 1.939030654 1.094380367 4.681445007 0.991156914 0.076461429 0.063473549 0.234596364 0.013315778 0.415115899 5.81E-05 4.23589871 3.58706464 up QWYESHYALPLGR ddPTM_HeLa_Curcumin_4h_R1 2 QWYESHYALPLGR 13 0 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 0 ; ; 172.33 0.00016198 55227000 3887.3 2455 3474.9 2396.3 3364.2 14701.7 7250.7 6816.9 3595.5 3277.6 FALSE FALSE TRUE 3579.616103 2667.199261 3603.682851 2386.384746 3324.084112 11652.4017 7454.135128 8895.341429 3201.082645 3391.496356 1.055468067 0.786437307 1.06256427 0.703637715 0.980123156 3.435770077 2.197889765 2.622836794 0.943855546 1 11.72770623 -5.277403846 24.9783597 0.983641332 2.696737929 0.881435339 0.305126523 167.5374933 262132.7146 0.039558739 0.08872004 5.28E-06 5.277403846 1.713096597 QY(ph)SGLLLEIQRLRT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 QYSGLLLEIQRLRTR 15 2 H0YMG0 H0YMG0 ZFAND6 2 0 QY(0.968)S(0.032)GLLLEIQRLRT(1)R 90.614 0.0029638 18948000 908 570.91 799.4 887.57 815.17 736.95 615.24 520.32 939.9 670.33 TRUE FALSE FALSE 836.1308419 620.2569165 829.0264672 883.8974705 805.4496302 584.0982629 632.5019786 678.9631727 836.7953215 693.6239176 1.205452725 0.894226541 1.195210324 1.274318039 1.161219516 0.842096485 0.911880289 0.978863553 1.206410708 1 9.438009836 -5.264287889 24.9671768 1.108400524 0.911040125 0.446216751 0.111290011 202.2106295 1772385.572 0.017235701 0.04020958 5.44E-06 5.264287889 -0.1973604 QYDIDDAIAK ddPTM_HeLa_Curcumin_4h_R1 1 QYDIDDAIAK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 104.79 0.00022118 0 2155.3 1755.2 2073.9 1892.9 2097.1 2391 1649.4 1701 1855 1889.7 FALSE FALSE TRUE 1984.705731 1906.911667 2150.760558 1885.067681 2072.093452 1895.079648 1695.677725 2219.62707 1651.511141 1955.366934 1.015004241 0.975219348 1.099926832 0.964048051 1.059695454 0.9691683 0.867191572 1.135146059 0.844604208 1 10.93322365 QYPK(ac)FNFVGK ddPTM_HeLa_Curcumin_4h_R1 1 QYPKFNFVGK 10 1 Q07666-2;Q07666;Q5VWX1 Q07666-2 KHDRBS1;KHDRBS2 "KH domain-containing, RNA-binding, signal transduction-associated protein 1;KH domain-containing, RNA-binding, signal transduction-associated protein 2" 0 1 QYPK(1)FNFVGK 138.1 4.38E-12 0 200.72 0 169.8 174.84 130.57 267.2 226.45 102.57 199.01 168.02 FALSE TRUE FALSE 184.8328002 0 176.0929374 174.1165584 129.013038 211.779708 232.8035775 133.8431208 177.1791009 173.8586825 1.063120907 0 1.012850982 1.00148325 0.742056918 1.218114074 1.339039122 0.769838578 1.019098376 1 7.441771307 -3.968240091 15.33971013 0.97032608 0.154330774 0.009275481 0.34722284 5205837.712 72851868.19 0.046895282 109900134.2 0.000107587 3.968240091 -0.815995306 QYQDFLEDLEEDEAIRK ddPTM_HeLa_Curcumin_4h_R1 2 QYQDFLEDLEEDEAIRK 17 1 C9JA08;Q96D46 C9JA08 NMD3 60S ribosomal export protein NMD3 0 0 ; ; 125.86 0.00058522 6792000 1641.99 1483.95 1420.66 1512.31 1538.37 1661.45 1243.03 1130.33 1692.93 1369.15 FALSE FALSE TRUE 1512.024759 1612.216026 1473.310909 1506.052462 1520.025942 1316.846542 1277.906076 1474.962414 1507.219815 1416.727861 1.067265493 1.137985686 1.03993925 1.063049936 1.072913144 0.929498585 0.902012385 1.041104968 1.063873914 1 10.46834694 -5.259812648 24.99151619 1.046027266 0.951986017 0.477904832 0.048310816 109.960946 1689314.238 0.007447311 0.017928076 5.50E-06 5.259812648 -0.094041249 RAAAASAAEAGIATT(ph)GTEDSDDALLK ddPTM_HeLa_Curcumin_4h_R1 1 RAAAASAAEAGIATTGTEDSDDALLK 26 1 H0Y3Y9;P55036 H0Y3Y9 PSMD4 26S proteasome non-ATPase regulatory subunit 4 1 0 RAAAASAAEAGIAT(0.025)T(0.35)GT(0.35)EDS(0.274)DDALLK 55.588 0.0057061 0 982.19 829.8 834.47 940.28 1049.7 1218.5 1083.1 747.32 1180.9 1095 TRUE FALSE FALSE 904.4486251 901.5242145 865.3961923 936.3893705 1037.183013 965.7693647 1113.488871 975.1744278 1051.358224 1133.051168 0.798241642 0.795660637 0.763775032 0.826431671 0.915389386 0.852361651 0.982734851 0.860662303 0.92790004 1 10.1459973 -9.392242182 1.138032714 0.999310643 0.846708961 0.324654461 0.063242906 0.372872017 0.869753065 0.044360842 0.011553142 4.05E-10 9.392242182 -0.152601682 RAADEDWDS(ph)ELEDDLLGEDLLSGK ddPTM_HeLa_Curcumin_4h_R1 1 RAADEDWDSELEDDLLGEDLLSGK 24 1 Q96EV2;A8MTF7;Q96EV2-2 Q96EV2 RBM33 RNA-binding protein 33 1 0 RAADEDWDS(0.998)ELEDDLLGEDLLS(0.002)GK 47.159 0.016319 8727700 510.83 411.3 577.25 449.1 527.02 602.1 424.84 396.97 418.87 441.78 TRUE FALSE FALSE 470.3972665 446.8509393 598.6433928 447.2417432 520.7356307 477.2176729 436.759867 518.0043256 372.921009 457.1318221 1.02901886 0.977510026 1.309564033 0.97836493 1.13913669 1.043938859 0.955435272 1.133161816 0.815784399 1 8.836466442 RAAEDDEDDDVDTK ddPTM_HeLa_Curcumin_4h_R1 4 RAAEDDEDDDVDTK 14 1 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA "Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1" 0 0 ;;; ;;; 196.97 3.57E-06 124383000 16175.1 13794.5 14482.7 15715.5 14820.7 18655.3 14676.2 15111.6 17632 15611.4 FALSE FALSE TRUE 14894.82377 14986.83511 15019.4416 15650.47343 14643.97283 14785.98049 15087.97467 19719.05727 15697.81371 16153.89499 0.922057731 0.927753655 0.929772146 0.968835902 0.906528911 0.915319835 0.934014656 1.220699855 0.971766483 1 13.97959445 -4.2593983 24.93368034 0.949865414 1.220699951 0.892737827 0.028881911 53.49915483 653491.6259 0.005235552 0.046203839 5.50E-05 4.2593983 0.270834538 RAAEDDEDDDVDTK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 RAAEDDEDDDVDTKK 15 2 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA "Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1" 0 1 ; RAAEDDEDDDVDTK(1)K;RAAEDDEDDDVDTK(1)K 213.83 2.69E-21 8729100 3317.9 3218.7 2789.57 2940.2 4115.3 5074.5 3714.2 4346.2 4787.2 3251.5 FALSE TRUE FALSE 3055.284714 3496.910086 2892.953918 2928.034231 4066.227735 4021.991499 3818.410456 5671.336373 4262.056137 3364.489383 0.908097594 1.039358336 0.859849323 0.870275961 1.208572022 1.195424042 1.134915294 1.685645495 1.266776515 1 11.71617185 -1 0.617686296 0.954255056 50.58666136 0.643810364 0.140093506 50.90855721 0.341740197 0.017324358 3436.575196 0.1 1 49.63240631 RAAEDDEDDDVDTKK ddPTM_HeLa_Curcumin_4h_R1 5 RAAEDDEDDDVDTKK 15 2 B8ZZQ6;P06454-2;P06454;B8ZZA1;B8ZZW7;H7C2N1 B8ZZQ6 PTMA "Prothymosin alpha;Prothymosin alpha, N-terminally processed;Thymosin alpha-1" 0 0 ;;;; ;;;; 135.02 0.00024238 264428700 22196.3 17828.7 17833.6 21061.5 18680.7 23365 18577.9 19303.1 22479.4 19169 FALSE FALSE TRUE 20439.43943 19369.73338 18494.5289 20974.35309 18457.94485 18518.83562 19099.14587 25188.52633 20013.46606 19835.12132 1.030467074 0.976537177 0.932413198 1.05743508 0.93056879 0.933638636 0.962895339 1.269895249 1.008991361 1 14.2757696 -4.257199679 24.87598061 0.99599108 1.269895365 0.794878872 0.043396861 146.1093791 857245.337 0.006412883 0.066111862 5.53E-05 4.257199679 0.273904285 RAAEEAEEAR ddPTM_HeLa_Curcumin_4h_R1 2 RAAEEAEEAR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 147.91 2.59E-06 841160 1058.82 1190.69 809.41 989.2 924.79 1186.58 485.53 647.05 1017.64 1130.63 FALSE FALSE TRUE 975.0132797 1293.607938 839.4074466 985.1069525 913.7624833 940.4699325 499.1526651 844.3325663 906.007438 1169.919308 0.833402161 1.105724069 0.717491745 0.842029827 0.781047442 0.803875896 0.426655635 0.72170154 0.774418741 1 10.19219331 -3.309145653 0.247083382 0.975818444 1.66E-06 0.338453864 0.138437272 9.760310357 0.322927607 0.078350484 3.147170707 0.000490743 3.309145653 -0.975816788 RAAEEEDEADPKR ddPTM_HeLa_Curcumin_4h_R1 1 RAAEEEDEADPKR 13 2 P20962 P20962 PTMS Parathymosin 0 0 119.39 0.00098783 3734500 2375.3 1792.5 1698.7 1825.6 2019.6 2444.3 1801.6 2218.7 2872.9 2266 FALSE FALSE TRUE 2187.292499 1947.435713 1761.655316 1818.046151 1995.517589 1937.324627 1852.148047 2895.171416 2557.750058 2344.743331 0.932849438 0.830553898 0.751321176 0.775371072 0.851060141 0.826241662 0.789915051 1.234749824 1.090844368 1 11.19521429 -7.577078036 2.109622875 0.975810616 0.853493374 0.176413176 0.134999155 0.405318723 3.688353106 0.024165762 0.025490015 2.65E-08 7.577078036 -0.122317242 RAAPTT(ph)PPPPVK ddPTM_HeLa_Curcumin_4h_R1 2 RAAPTTPPPPVK 12 1 Q9NZQ3-5;Q9NZQ3-4;Q9NZQ3-3;Q9NZQ3-2;Q9NZQ3;C9JC20;C9JMQ4;C9JSC3 Q9NZQ3-5 NCKIPSD NCK-interacting protein with SH3 domain 1 0 RAAPT(0.055)T(0.945)PPPPVK;RAAPT(0.092)T(0.908)PPPPVK ; 87.363 0.0092401 299790000 13003 9883 10234.9 10843.9 10793.9 11447.9 9442 5624.3 12500.6 10539.5 TRUE FALSE FALSE 11973.79883 10737.24248 10614.2144 10799.03082 10665.18979 9073.476496 9706.917108 7339.123179 11129.31545 10905.74684 1.097934787 0.984549031 0.973267998 0.990214698 0.977942176 0.831990383 0.890073578 0.672959247 1.020500074 1 13.41280095 -3.322521722 0.467777913 1.0432055 6.84E-19 0.839958518 0.045152752 2.89296758 0.224150918 0.011176264 2.029443351 0.000475859 3.322521722 -1.0432055 RADAGEK(ac)PK ddPTM_HeLa_Curcumin_4h_R1 1 RADAGEKPK 9 2 A0A1B0GVU9;P47897-2;P47897;B4DDN1;A0A0U1RQX9;A0A0U1RQX5;H7C0R3 A0A1B0GVU9 QARS Glutamine--tRNA ligase 0 1 RADAGEK(1)PK 84.31 0.0075558 839450 464.51 549.97 303.23 338.57 393.56 494.7 391.34 367.43 410.82 545.92 FALSE TRUE FALSE 427.7435434 597.5069562 314.4679705 337.169087 388.867054 392.0936436 402.3199472 479.4577156 365.7540738 564.8906794 0.75721473 1.057739095 0.556688191 0.596874934 0.688393468 0.694105352 0.712208507 0.848761952 0.647477622 1 9.141827886 -8.977612271 0.382625574 1.065131508 0.700324055 0 0.167735341 1.681247443 0.381224625 0.253716302 0.052723174 1.05E-09 8.977612271 -0.364807453 RADLEETDK ddPTM_HeLa_Curcumin_4h_R1 1 RADLEETDK 9 1 Q7Z6E1;K7EPW3;P10072-2;P10072 Q7Z6E1 HKR1 Krueppel-related zinc finger protein 1 0 0 143.61 0.013129 80123000 6854.6 5891.4 6061.6 5879.5 7095.8 7318 6239 6310 6292.4 5581.8 FALSE FALSE TRUE 6312.051177 6400.626364 6286.248228 5855.172187 7011.187219 5800.164309 6414.049549 8233.889952 5602.139463 5775.767135 1.092850704 1.108186361 1.088383254 1.013747966 1.213897142 1.004224058 1.110510413 1.425592438 0.969938596 1 12.49579686 -4.27084915 3.622280081 1.060186323 1.463280747 0.723649076 0.067074586 0.099189693 2.361770319 0.008793417 0.10634627 5.36E-05 4.27084915 0.403094424 RADLNQGIGEPQS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 RADLNQGIGEPQSPSR 16 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 0 RADLNQGIGEPQS(0.5)PS(0.5)R;RADLNQGIGEPQS(0.5)PS(0.5)R ; 112.82 0.0006628 110649000 8646.9 8121.6 8836.4 8584.7 10609.7 10846.2 8670.9 4356 8981.3 7608.6 TRUE FALSE FALSE 7962.488741 8823.594915 9163.884757 8549.178786 10483.18626 8596.575858 8914.182117 5684.124347 7996.07386 7872.998284 1.011366757 1.120741374 1.163963769 1.085886022 1.331536713 1.091906228 1.132247436 0.721977085 1.015632618 1 12.94269745 -7.271795426 17.74878491 1.005367401 1.105781364 0.06193605 0.142597045 25.15724695 43115.24957 0.023223412 0.026837892 5.35E-08 7.271795426 0.100413963 RADLNQGIGEPQSPS(ph)RR ddPTM_HeLa_Curcumin_4h_R1 1 RADLNQGIGEPQSPSRR 17 2 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 0 RADLNQGIGEPQS(0.056)PS(0.944)RR 86.548 0.0043686 57978000 1033 1229.7 1302.4 1101.3 785.12 1690.4 1248.1 482.97 1534.5 1386.7 TRUE FALSE FALSE 951.23696 1335.989789 1350.66809 1096.743112 775.7579568 1339.791985 1283.118327 630.2253297 1366.169189 1434.887722 0.662934769 0.931076187 0.941305769 0.764340719 0.54064018 0.933726009 0.89422908 0.43921578 0.952108774 1 10.48672214 -9.504964017 1.18307062 1.003394985 0.764872065 0.208756391 0.165025128 0.609309093 1.490745459 0.121479926 0.027698159 3.13E-10 9.504964017 -0.23852292 MCSHFAQDLWPEQSMKDS(ph)FQKVVLR ddPTM_HeLa_Curcumin_4h_R1 1 MCSHFAQDLWPEQSMKDSFQKVVLR 25 2 M0QY39;Q68DY1-2 M0QY39 ZNF626 1 0 MCS(0.005)HFAQDLWPEQS(0.021)MKDS(0.974)FQKVVLR 42.041 0.018484 12409000 1192.6 960.29 927.93 929.7 956.48 1266.3 812.2 112.8 1199.2 907.88 TRUE FALSE FALSE 1098.204452 1043.293189 962.3199021 925.8531477 945.0746007 1003.655106 834.9881461 147.1922007 1067.65076 939.4287624 1.169013017 1.110561258 1.024367084 0.985549075 1.006009863 1.068367444 0.888825401 0.156682664 1.136489325 1 9.875639955 -4.27213177 2.663616289 1.066655505 2.28E-22 0.955502055 0.058453237 0.081480775 0.766139072 0.010566843 0.189803318 5.34E-05 4.27213177 -1.066655505 down RAEDGS(ph)VIDYELIDQDAR ddPTM_HeLa_Curcumin_4h_R1 3 RAEDGSVIDYELIDQDAR 18 1 P07355;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YNP5;H0YN28;H0YL33;H0YNA0;P07355-2 P07355;P07355-2 ANXA2 Annexin A2;Annexin 1 0 RAEDGS(1)VIDYELIDQDAR;RAEDGS(1)VIDYELIDQDAR;RAEDGS(1)VIDYELIDQDAR ;; 199.31 1.61E-09 58973000 6592.3 4678.7 5360.7 6640 6145.2 8778.8 5315.4 6679.7 6627.7 4873.2 TRUE FALSE FALSE 6070.512499 5083.10598 5559.372258 6612.525439 6071.922504 6957.977923 5464.535818 8716.30978 5900.657892 5042.543337 1.203859262 1.008044084 1.102493699 1.31134727 1.204138883 1.379854858 1.083686436 1.728554263 1.170174949 1 12.29993586 -1 0.371283701 1.082419033 7.498866169 0.544973641 0.138444918 33.04441663 0.405362251 0.036046173 153.272593 0.1 1 6.416447136 RAEDGSVIDYELIDQDAR ddPTM_HeLa_Curcumin_4h_R1 10 RAEDGSVIDYELIDQDAR 18 1 P07355;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YNP5;H0YN28;H0YL33;H0YNA0;P07355-2 P07355;P07355-2 ANXA2 Annexin A2;Annexin 0 0 ;;;;;;;;; ;;;;;;;;; 235.02 5.77E-24 1934133400 16934.8 15098.7 16422.3 18305 16780.6 20999.4 16836.6 18912.5 19972.7 15528.22 FALSE FALSE TRUE 15594.39271 16403.76435 17030.92488 18229.25876 16580.5023 16643.88773 17308.98968 24678.83419 17781.74478 16067.82449 0.970535415 1.020907613 1.059939689 1.13451941 1.031907108 1.035851975 1.077245379 1.53591634 1.10666785 1 13.97188699 -4.222681794 2.708399191 1.0101935 1.668876989 0.870916622 0.055086192 0.124400279 1.104385435 0.007756678 0.190513078 5.99E-05 4.222681794 0.658683489 RAEDGSVIDYELIDQDARDLYDAGVKR ddPTM_HeLa_Curcumin_4h_R1 1 RAEDGSVIDYELIDQDARDLYDAGVKR 27 3 P07355;H0YN42;H0YMU9;H0YMD0;H0YM50;H0YNP5;H0YN28;H0YL33;P07355-2 P07355;P07355-2 ANXA2 Annexin A2;Annexin 0 0 65.881 0.00018745 2867800 617.83 605.11 365.15 534.86 215.1 637.22 318.59 425.44 1786.2 958.74 FALSE FALSE TRUE 568.9281036 657.4130121 378.6827802 532.646891 212.535073 505.0533891 327.528778 555.1546975 1590.258329 992.0561436 0.573483776 0.662677225 0.38171507 0.536912043 0.21423694 0.509097587 0.330151454 0.55960008 1.602992269 1 9.954277959 -8.790866505 0.360411086 1.129287725 0.388798407 0.650171936 0.224446322 0.639777205 0.143693052 0.190102803 0.048601545 1.62E-09 8.790866505 -0.740489318 RAEFTVETR ddPTM_HeLa_Curcumin_4h_R1 1 RAEFTVETR 9 1 P21333-2;P21333;F8WE98;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 134.84 0.0046267 10473000 3399.7 2416.1 2813.4 2552.4 3327.8 3720 2795.5 2818.8 2579.3 2831.6 FALSE FALSE TRUE 3130.610158 2624.936918 2917.667079 2541.838845 3288.118158 2948.430067 2873.934206 3678.239144 2296.357243 2929.997889 1.0684684 0.895883553 0.995791529 0.867522415 1.122225436 1.00629085 0.980865623 1.255372626 0.783740238 1 11.51668391 -4.256818038 24.26287177 1.012098052 1.255372777 0.355964959 0.101627915 200.4555293 1052368.821 0.009855847 0.105167838 5.54E-05 4.256818038 0.243274725 NKAGT(ph)PVSELTK ddPTM_HeLa_Curcumin_4h_R1 1 NKAGTPVSELTK 12 1 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 0 NKAGT(0.775)PVS(0.135)ELT(0.091)K 149.32 0.0057388 36928000 4751 3489.6 3910.2 4368.9 3272.1 3896.7 2940.8 1125.5 4506.6 4485.9 TRUE FALSE FALSE 4374.953337 3791.225475 4055.115452 4350.822649 3233.082345 3088.480495 3023.310933 1468.659769 4012.237255 4641.784691 0.942515353 0.816760304 0.873611277 0.937316773 0.696517086 0.665364876 0.651325112 0.316399805 0.864373839 1 12.18046389 -4.271391268 0.436274627 0.978615181 1.91E-17 0.835161013 0.07791229 1.091431997 0.140295418 0.01637802 0.551540465 5.35E-05 4.271391268 -0.978615181 down IHFS(ph)PSEPK ddPTM_HeLa_Curcumin_4h_R1 1 IHFSPSEPK 9 0 Q8IZT6-2;Q8IZT6 Q8IZT6-2 ASPM Abnormal spindle-like microcephaly-associated protein 1 0 IHFS(0.991)PS(0.009)EPK 118.28 0.0031567 6389700 7392.7 6372.1 6824 7670.2 6773 10329 6452.7 1528.8 8024.8 7725.9 TRUE FALSE FALSE 6807.559994 6922.87593 7076.903443 7638.462745 6692.236399 8186.648968 6633.745395 1994.924082 7144.499517 7994.37445 0.8515438 0.865968435 0.885235422 0.95547973 0.837118206 1.024051227 0.829801686 0.249540986 0.893690877 1 12.96476943 -4.271333118 3.667476684 0.921293955 0.182564615 0.916971824 0.059563042 0.057254388 1.419964891 0.009552768 0.113348506 5.35E-05 4.271333118 -0.73872934 down RAFLS(ph)ADER ddPTM_HeLa_Curcumin_4h_R1 1 RAFLSADER 9 1 H7C347;Q8N819-2;Q8N819 H7C347 PPM1N Probable protein phosphatase 1N 1 0 RAFLS(1)ADER 81.594 0.014241 999390 0 120.95 0 0 0 73.94 0 0 0 0 TRUE FALSE FALSE 0 131.4043791 0 0 0 58.60401052 0 0 0 0 0 RAGDLLEDS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 5 RAGDLLEDSPK 11 1 P51858;P51858-2;P51858-3 P51858 HDGF Hepatoma-derived growth factor 1 0 RAGDLLEDS(1)PK;RAGDLLEDS(1)PK;RAGDLLEDS(1)PK;RAGDLLEDS(1)PK;RAGDLLEDS(1)PK ;;;; 137.09 0.0028087 1004194000 20783.5 19988 22635 20398.4 24194.4 21249.2 20946.7 20034.2 20211.4 17402.1 TRUE FALSE FALSE 19138.46404 21715.67366 23473.87301 20313.99683 23905.89758 16841.87639 21534.40803 26142.53535 17994.25999 18006.82168 1.062845203 1.205969273 1.303610011 1.128127839 1.327602284 0.935305335 1.195902776 1.451812864 0.999302393 1 14.13625594 -7.34629453 2.948860468 1.025941791 1.213819026 0.340995429 0.128259534 0.23354216 3.819623546 0.022113514 0.025367922 4.51E-08 7.34629453 0.187877236 RAGELTEDEVER ddPTM_HeLa_Curcumin_4h_R1 3 RAGELTEDEVER 12 1 P62269 P62269 RPS18 40S ribosomal protein S18 0 0 ;; ;; 189.3 9.20E-06 42459200 7677.5 5814.8 5802.3 6394.9 5827.5 7650.6 5750.5 6298.1 6945.5 6757.8 FALSE FALSE TRUE 7069.817774 6317.405402 6017.338342 6368.439598 5758.010869 6063.77932 5911.843553 8218.361697 6183.596027 6992.633047 1.011038006 0.903437283 0.860525399 0.910735563 0.823439587 0.867166814 0.845438837 1.17528857 0.884301519 1 12.77162008 -7.258885645 22.37671232 1.005212397 0.902515462 0.003595141 0.100835294 58.03350154 508506.7538 0.01467748 0.017520715 5.51E-08 7.258885645 -0.102696935 RAILGSYDSELT(ph)PAEYSPQLTR ddPTM_HeLa_Curcumin_4h_R1 1 RAILGSYDSELTPAEYSPQLTR 22 1 C9J9H5;C9JX80 C9J9H5 MAD1L1 1 0 RAILGSYDS(0.001)ELT(0.817)PAEY(0.018)S(0.161)PQLT(0.003)R 58.107 0.006232 5892600 1036 895.52 836.51 1051.7 792.76 992.19 845.62 817.39 1115.7 1050 TRUE FALSE FALSE 953.9995068 972.9247584 867.5117965 1047.348344 783.3068548 786.3986097 869.3458213 1066.608448 993.3105013 1086.487422 0.878058492 0.895477241 0.798455444 0.963976502 0.72095345 0.723799092 0.800143475 0.981703448 0.914240222 1 10.08545576 -8.471975409 0.395704018 1.020774186 0.816609926 0.206133363 0.08657527 1.176604025 0.3801686 0.100820103 0.036058421 3.37E-09 8.471975409 -0.20416426 RALLET(ph)ASPR ddPTM_HeLa_Curcumin_4h_R1 1 RALLETASPR 10 1 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2 Q96BT3 CENPT Centromere protein T 1 0 RALLET(0.628)AS(0.372)PR 107.93 0.0044491 8279400 3900.1 2503.2 3146.3 2958.2 3300.4 3994.4 3144.1 1072 3769 2966.8 TRUE FALSE FALSE 3591.40297 2719.565454 3262.904646 2945.959752 3261.044886 3165.916414 3232.314984 1398.847865 3355.55013 3069.896079 1.169877702 0.885881927 1.062871368 0.959628494 1.062265563 1.031278041 1.052906972 0.455666195 1.093050072 1 11.5839741 -4.261430804 10.75220831 1.053767887 0.454742078 0.84328628 0.074581745 0.02123873 117.0042398 0.01184628 0.091562024 5.48E-05 4.261430804 -0.599025809 RALLETAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 RALLETASPR 10 1 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2 Q96BT3 CENPT Centromere protein T 1 0 RALLET(0.005)AS(0.995)PR 91.307 0.0085987 7127000 3270 2503.4 2640 2544 2676.8 3198.7 2765.3 1129.3 3129.8 2737.1 TRUE FALSE FALSE 3011.17605 2719.782741 2737.840722 2533.473602 2644.880908 2535.253563 2842.886876 1473.618371 2786.46877 2832.214021 1.063188031 0.960302689 0.966678613 0.894520535 0.933856301 0.895149005 1.003768378 0.520306149 0.983848237 1 11.46771457 -3.984950826 2.068956647 0.998653204 1.60E-09 0.818467041 0.060700242 0.71767949 1.614606271 0.010196927 1.765317165 0.000103526 3.984950826 -0.998653203 RALS(ph)SAGPIPIRPPIVPVK ddPTM_HeLa_Curcumin_4h_R1 2 RALSSAGPIPIRPPIVPVK 19 2 Q765P7;A0A087WXN9 Q765P7 MTSS1L MTSS1-like protein 1 0 RALS(0.794)S(0.206)AGPIPIRPPIVPVK;RALS(0.859)S(0.141)AGPIPIRPPIVPVK ; 67.866 0.0033926 38612000 7185.3 6094.9 6339.4 7280.1 6734 8550.5 6172.4 7214.3 6357.6 6835.9 TRUE FALSE FALSE 6616.575923 6621.715998 6574.343741 7249.976875 6653.701448 6777.029916 6345.580932 9413.906859 5660.187186 7073.447016 0.935410403 0.936137075 0.929439879 1.024956695 0.940658979 0.958094392 0.897098814 1.330879674 0.800202104 1 12.78819772 -4.255323943 24.98661579 0.961430529 1.330879838 0.777823212 0.06199932 154.4841866 631177.7885 0.005270974 0.065098832 5.55E-05 4.255323943 0.369449309 RALS(ph)SDSILSPAPDAR ddPTM_HeLa_Curcumin_4h_R1 3 RALSSDSILSPAPDAR 16 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 RALS(0.712)S(0.257)DS(0.032)ILSPAPDAR;RALS(0.754)S(0.241)DS(0.005)ILSPAPDAR;RALS(0.661)S(0.159)DS(0.18)ILSPAPDAR ;; 151.64 0.00016047 364995000 7723.8 6504.6 5962.9 6504.6 6340.1 11350.9 8431.2 9386.5 9406.1 7543.1 TRUE FALSE FALSE 7112.45308 7066.82864 6183.89032 6477.685689 6264.498448 8996.595389 8667.756781 12248.40064 8374.274363 7805.222164 0.911242874 0.905397501 0.792276016 0.829916888 0.802603477 1.152637965 1.110507376 1.569257144 1.072906599 1 12.93022398 -4.040430858 1.182479689 0.925441823 2.126105402 0.790211973 0.101450093 0.791434093 0.647480134 0.014882538 1.3182292 9.11E-05 4.040430858 1.200663579 IGVAKPLPLS(ph)PEEGYVSAK ddPTM_HeLa_Curcumin_4h_R1 1 IGVAKPLPLSPEEGYVSAK 19 1 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 0 IGVAKPLPLS(0.99)PEEGY(0.003)VS(0.007)AK 95.591 0.00061321 13686000 913.94 881.19 1148.6 999.61 959.63 1890.6 1735.2 6427.4 1292.4 1042 TRUE FALSE FALSE 841.6006846 957.3561371 1191.168126 995.4738787 948.187039 1498.468249 1783.885042 8387.084672 1150.626953 1078.209422 0.780554007 0.887912976 1.104765087 0.923265794 0.879408971 1.389774767 1.654488455 7.778715802 1.067164624 1 10.07442171 -4.235690802 3.053469743 0.940942712 9.099878591 0.992517173 0.175270603 0.026688278 0.348329562 0.027545053 0.540113017 5.81E-05 4.235690802 8.15893588 up RALSSDS(ph)ILSPAPDAR ddPTM_HeLa_Curcumin_4h_R1 1 RALSSDSILSPAPDAR 16 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 RALS(0.113)S(0.01)DS(0.877)ILSPAPDAR 205.33 3.36E-10 67507000 2808.3 2306.8 1995.5 2409.3 2235.1 4230.8 2985.2 3138.6 3221.3 2773 TRUE FALSE FALSE 2586.020092 2506.189513 2069.454985 2399.330955 2208.447892 3353.284389 3068.956678 4095.544692 2867.931449 2869.361544 0.901252788 0.873431066 0.721224898 0.836189835 0.769665258 1.16865175 1.069560817 1.42733658 0.999501598 1 11.48651405 -4.254944507 1.19446974 0.913176127 1.646060178 0.682649135 0.11179626 0.776719813 0.893540357 0.017848237 0.707687619 5.56E-05 4.254944507 0.732884051 RALVEFESNPEET(ph)REPGSPPSVQR ddPTM_HeLa_Curcumin_4h_R1 2 RALVEFESNPEETREPGSPPSVQR 24 2 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 0 RALVEFESNPEET(0.974)REPGS(0.025)PPS(0.001)VQR;RALVEFESNPEET(0.98)REPGS(0.012)PPS(0.008)VQR ; 107.92 6.81E-06 88406000 2693.3 1693.06 1848.54 2296.7 1894.59 2316.2 1736.03 1490.14 2621.7 2440.7 TRUE FALSE FALSE 2480.122463 1839.400562 1917.048519 2287.196864 1871.998252 1835.794011 1784.73833 1944.476826 2334.106069 2525.514143 0.982026757 0.728327167 0.759072573 0.905636134 0.741234515 0.726899121 0.706683166 0.769933058 0.924210255 1 11.30236141 -7.26865527 23.93159609 0.991512647 0.76357241 0.737308689 0.055907928 93.96010035 311619.3185 0.00907458 0.010497467 5.39E-08 7.26865527 -0.227940237 RAPFDLFENK ddPTM_HeLa_Curcumin_4h_R1 4 RAPFDLFENK 10 1 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 0 ;;; ;;; 132.25 0.0019518 31723400 19392.7 12979 16936.6 14192.6 17063.6 15761 14624 15216.6 14531.1 16294.8 FALSE FALSE TRUE 17857.74733 14100.84693 17564.28529 14133.87478 16860.12771 12491.99094 15034.31008 19856.07129 12937.07469 16861.04309 1.059112846 0.836297426 1.041708108 0.838256252 0.999945711 0.740878893 0.891659549 1.177630066 0.767276059 1 14.04140617 -7.28478474 24.83580616 1.027914401 0.926599088 0 0.142479081 1001.540453 1065479.446 0.01873438 0.021429958 5.19E-08 7.28478474 -0.101315313 RAPFDLFENK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 RAPFDLFENKK 11 2 P08238;Q58FF7 P08238 HSP90AB1;HSP90AB3P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3 0 1 ; RAPFDLFENK(1)K;RAPFDLFENK(1)K 196.27 4.57E-17 9617900 4567.1 5378.4 3909.8 3609.1 7995.4 9520.7 8933.1 9097.3 9572.1 4425.9 FALSE TRUE FALSE 4205.609216 5843.28493 4054.700627 3594.1665 7900.060077 7545.9995 9183.738744 11871.02489 8522.064578 4579.699696 0.9183155 1.275910064 0.885363866 0.78480397 1.725017054 1.647706182 2.005314618 2.592096792 1.860834802 1 12.16103728 -4.657791858 0.733073353 0.9609858 3.023885039 0.616779613 0.348499569 0.412229306 0.215470314 0.033171828 0.622840646 2.20E-05 4.657791858 2.062899239 RAPFDLFENR ddPTM_HeLa_Curcumin_4h_R1 2 RAPFDLFENR 10 1 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 ; ; 141.89 0.002045 67357000 10085 5761.4 8034.4 6742.5 8549.2 5740.9 7162.9 6159 8088.5 8287.4 FALSE FALSE TRUE 9286.761608 6259.389744 8332.161932 6714.601322 8447.256374 4550.172627 7363.871696 8036.850747 7201.211786 8575.386533 1.082955453 0.729925085 0.971636894 0.78300859 0.985058381 0.530608458 0.858721839 0.937199824 0.839753609 1 13.06598599 -7.270492823 24.98631106 1.039173412 0.827596591 0.137957857 0.141941162 477.6040489 1318121.757 0.020666476 0.02381088 5.36E-08 7.270492823 -0.211576821 RAPQY(ph)T(ph)FGY(ph)RR ddPTM_HeLa_Curcumin_4h_R1 1 RAPQYTFGYRR 11 2 Q8IXM7 Q8IXM7 ODF3L1 Outer dense fiber protein 3-like protein 1 3 0 RAPQY(1)T(1)FGY(1)RR 57.225 0.0096243 0 373.19 802.84 300.5 414.93 298.15 341.44 276.61 159.06 321.72 447.75 TRUE FALSE FALSE 343.6516177 872.2339122 311.6367943 413.2131296 294.594756 270.6214952 284.3709321 207.5566618 286.4281209 463.3092792 0.741732646 1.882616972 0.672632318 0.8918732 0.63584903 0.584105494 0.613782078 0.447987276 0.618222284 1 8.855831767 -5.758730168 1.789290471 0.950263382 0.54982937 0.258493264 0.334007567 0.401762518 2.610758282 0.049594043 0.114025353 1.74E-06 5.758730168 -0.400434011 RAPS(ph)TSPSFEGTQETYTVAHEENVR ddPTM_HeLa_Curcumin_4h_R1 1 RAPSTSPSFEGTQETYTVAHEENVR 25 1 Q9BUT9 Q9BUT9 FAM195A Protein FAM195A 1 0 RAPS(0.25)T(0.25)S(0.25)PS(0.25)FEGT(0.001)QETYTVAHEENVR 73.459 0.00048902 19782000 2207.7 1696.3 1694.1 1780.6 2088.2 2440.5 1737.9 1732.2 2307.4 2113.6 TRUE FALSE FALSE 2032.958215 1842.920613 1756.884836 1773.232349 2063.299579 1934.31279 1786.660797 2260.339806 2054.283993 2187.047443 0.929544634 0.842652325 0.803313546 0.810788241 0.943417842 0.884440251 0.81692823 1.033512013 0.939295578 1 11.0947688 -7.879413412 1.3019996 0.981528669 0.873325962 0.208910284 0.068817499 0.321850277 1.139837384 0.015532866 0.013911093 1.32E-08 7.879413412 -0.108202707 RAPSS(ph)PVAK ddPTM_HeLa_Curcumin_4h_R1 1 RAPSSPVAK 9 1 Q9GZR2;A0A0C4DG31;Q9GZR2-2 Q9GZR2 REXO4 RNA exonuclease 4 1 0 RAPS(0.006)S(0.994)PVAK 75.566 0.017921 5301200 2610.1 3734.2 2780.7 2666 3410.7 3689.2 2951.1 1464 2675.8 2785.7 TRUE FALSE FALSE 2403.507831 4056.967609 2883.755188 2654.968798 3370.02963 2924.018334 3033.899924 1910.366861 2382.271435 2882.502868 0.833826692 1.407446166 1.000434456 0.921063715 1.16913314 1.014402576 1.052522777 0.662745866 0.826459346 1 11.49310633 RAPSSPVAKPGPVK(ac)TLTR ddPTM_HeLa_Curcumin_4h_R1 1 RAPSSPVAKPGPVKTLTR 18 3 Q9GZR2;A0A0C4DG31;Q9GZR2-2 Q9GZR2 REXO4 RNA exonuclease 4 0 1 RAPSSPVAK(0.012)PGPVK(0.988)TLTR 54.953 0.015691 3307100 755.06 728.72 646.31 595.06 532.29 987.15 568.57 470.48 684.4 1010.8 FALSE TRUE FALSE 695.2962043 791.7073097 670.2628172 592.5977994 525.9427894 782.4039625 584.522544 613.9271862 609.3230323 1045.925225 0.664766647 0.756944465 0.640832443 0.566577596 0.502849321 0.748049616 0.558856915 0.586970437 0.582568445 1 10.030564 -9.599356062 0.319311162 1.211919647 0.580398449 0 0.148730331 1.31546014 0.148129935 0.307293816 0.034433608 2.52E-10 9.599356062 -0.631521197 RAPSTSPS(ph)FEGTQETYTVAHEENVR ddPTM_HeLa_Curcumin_4h_R1 1 RAPSTSPSFEGTQETYTVAHEENVR 25 1 Q9BUT9 Q9BUT9 FAM195A Protein FAM195A 1 0 RAPS(0.075)T(0.075)S(0.075)PS(0.759)FEGT(0.015)QETYTVAHEENVR 90.06 2.53E-05 15932000 531.24 370.39 619.05 549.84 703.06 761.69 436.02 587.31 498.78 572.94 TRUE FALSE FALSE 489.1917934 402.4048612 641.9925376 547.5649078 694.6764687 603.706908 448.2535477 766.3781154 444.0650819 592.8496224 0.825153251 0.678763798 1.082892716 0.923615175 1.171758305 1.018313726 0.756099913 1.292702376 0.749034941 1 9.211522398 RAPSVANVGSHCDLS(ph)LKIPEISIQDMTAQVTSPSGK ddPTM_HeLa_Curcumin_4h_R1 1 RAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGK 36 2 P21333-2;P21333;Q60FE5 P21333-2;Q60FE5 FLNA Filamin-A 1 0 RAPS(0.011)VANVGS(0.135)HCDLS(0.462)LKIPEIS(0.389)IQDMT(0.003)AQVTSPSGK 53.1 0.00066185 2396500 526.53 287.68 431.95 509.98 527.48 501.24 525.01 420.57 350.48 286.52 TRUE FALSE FALSE 484.8545949 312.5457773 447.958447 507.8698379 521.1901455 397.2771739 539.7403676 548.7998569 312.0332209 296.4765487 1.635389366 1.054200674 1.510940575 1.713018585 1.757947291 1.339995273 1.820516226 1.851073413 1.052471847 1 8.211774182 -11.32939435 0.18132276 4.94E-19 1.779533814 0.58296231 0.206648402 15.1732812 0.360830856 6.467590617 0.358671213 4.68E-12 11.32939435 1.779533814 RAQS(ph)TDSLGTSGSLQSK ddPTM_HeLa_Curcumin_4h_R1 1 RAQSTDSLGTSGSLQSK 17 1 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 1 0 RAQS(0.956)T(0.027)DS(0.016)LGTSGSLQSK 216.34 4.30E-45 0 4098 3065.3 2815.5 3496.1 2848.4 4043 2938.2 6287.5 4394.6 3522.2 TRUE FALSE FALSE 3773.638976 3330.250873 2919.844907 3481.634065 2814.43469 3204.436226 3020.637984 8204.529806 3912.523375 3644.596188 1.035406608 0.913750304 0.801143599 0.955286645 0.772221268 0.879229429 0.828799085 2.251149204 1.073513545 1 11.83154326 -4.257990428 24.99500393 0.956837346 2.25114969 0.938340971 0.102102341 63.94944263 463428.8686 0.015781833 0.154300401 5.52E-05 4.257990428 1.294312344 RAQSTDS(ph)LGT(ph)SGSLQSK ddPTM_HeLa_Curcumin_4h_R1 1 RAQSTDSLGTSGSLQSK 17 1 I3L456;Q15276-2;Q15276 I3L456 RABEP1 Rab GTPase-binding effector protein 1 2 0 RAQS(0.018)T(0.04)DS(0.815)LGT(0.767)S(0.279)GS(0.081)LQSK 103.46 0.0025242 16889000 5150.1 4302.2 4080.4 5253.6 4232.2 5743.6 3238.1 4006.7 6548.6 5862.7 TRUE FALSE FALSE 4742.464151 4674.062998 4231.623213 5231.861995 4181.733779 4552.312616 3328.952371 5228.324385 5830.234964 6066.428389 0.781755565 0.770480207 0.697547707 0.862428708 0.689323851 0.750410674 0.548749966 0.861845562 0.961065489 1 12.56663166 -9.4183066 0.312285097 1.133359408 0.704278917 0.552367752 0.085318422 1.957703811 0.233863703 0.304959848 0.042191121 3.82E-10 9.4183066 -0.429080491 RAS(ph)AILPGVLGSETLSNEVFQESEEEKQPEVPSSLAK ddPTM_HeLa_Curcumin_4h_R1 1 RASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLAK 37 2 Q9BZQ8 Q9BZQ8 FAM129A Protein Niban 1 0 RAS(0.994)AILPGVLGS(0.004)ET(0.002)LSNEVFQESEEEKQPEVPSSLAK 66.519 2.33E-06 15077000 977.97 848.6 753.73 750.17 605.85 1093.7 834.44 891.28 823.39 804.75 TRUE FALSE FALSE 900.5626426 921.9492027 781.6638968 747.0659953 598.6256344 866.8542915 857.8521406 1163.027169 733.066177 832.7150026 1.081477624 1.107160553 0.938693184 0.897144873 0.718884171 1.040997567 1.030186964 1.396668927 0.880332616 1 9.701679006 -4.254371665 4.038717369 1.00494392 1.433743792 0.540114337 0.114465856 0.160564492 5.451695675 0.016345985 0.201866214 5.57E-05 4.254371665 0.428799871 RAS(ph)GLSTEGATGPSADTSGSELDGR ddPTM_HeLa_Curcumin_4h_R1 1 RASGLSTEGATGPSADTSGSELDGR 25 1 Q7Z628 Q7Z628 NET1 Neuroepithelial cell-transforming gene 1 protein 1 0 RAS(0.959)GLS(0.039)T(0.002)EGATGPSADTSGSELDGR 124.02 1.86E-08 9352300 261.33 203.28 260.69 287.05 184.96 370.29 143.49 129.82 347.73 152.68 TRUE FALSE FALSE 240.6454547 220.8506174 270.3514007 285.8622632 182.7544728 293.48768 147.5159432 169.4015204 309.584889 157.9856186 1.523211143 1.397915958 1.711240574 1.809419526 1.15677917 1.857686051 0.9337302 1.07225912 1.959576395 1 7.303649426 -9.273090923 0.958963521 0.995276804 1.445190338 0 0.417992473 0.666969544 1.081652626 0.208999209 0.054370445 5.33E-10 9.273090923 0.449913534 RAS(ph)GQAFELILS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 RASGQAFELILSPR 14 1 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 2 0 RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR;RAS(1)GQAFELILS(1)PR ;; 122.3 0.00065416 216188000 8866.4 7504.93 8201.8 8482.7 8456.9 13610.3 12676.1 5035.86 10285 7934.77 TRUE FALSE FALSE 8164.615084 8153.622708 8505.765923 8447.600835 8356.056991 10787.37036 13031.75725 6571.270532 9156.761232 8210.502667 0.994411112 0.993072293 1.035961654 1.028877424 1.017727821 1.313850174 1.587205775 0.800349357 1.115249773 1 13.00325483 -5.27059777 21.378255 1.003542815 1.269142165 0.197081336 0.183713915 72.44058424 169099.3263 0.022803814 0.05187135 5.36E-06 5.27059777 0.26559935 RAS(ph)GQAFELILSPR ddPTM_HeLa_Curcumin_4h_R1 4 RASGQAFELILSPR 14 1 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 1 0 RAS(0.998)GQAFELILS(0.002)PR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR;RAS(1)GQAFELILSPR ;;; 151.11 0.00076279 892824000 4164.43 3171.71 3518.27 2898.23 3677.93 5720.05 3807.41 1208.39 4536.01 3930.4 TRUE FALSE FALSE 3834.810971 3445.85848 3648.660181 2886.237892 3634.073087 4533.647152 3914.235677 1576.822548 4038.421052 4066.981107 0.942913397 0.847276736 0.897142152 0.709675756 0.893555439 1.114745073 0.962442552 0.387713271 0.992977578 1 11.98974257 -4.260355017 24.84689734 0.945155829 0.387713078 0.714605489 0.102155898 35.45148857 812209.2692 0.014878569 0.122427484 5.49E-05 4.260355017 -0.557442751 RAS(ph)ISEPSDTDPEPR ddPTM_HeLa_Curcumin_4h_R1 2 RASISEPSDTDPEPR 15 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 0 RAS(0.994)IS(0.005)EPS(0.001)DT(0.001)DPEPR;RAS(0.998)IS(0.002)EPSDTDPEPR ; 152.94 0.0006472 62450000 2118.1 1977.19 2322.3 2238.01 1937.22 2692.2 2261 2309.74 2731.7 2300.7 TRUE FALSE FALSE 1950.45015 2148.089493 2408.366481 2228.749708 1914.119917 2133.807373 2324.437575 3013.969093 2432.039344 2380.649154 0.819293404 0.902312502 1.01164276 0.936194107 0.804032763 0.896313247 0.97638813 1.266028255 1.021586629 1 11.2171393 -4.268415861 2.922460616 0.911909564 1.323686689 0.668712742 0.07141366 0.189404249 2.314976503 0.011145915 0.181335112 5.39E-05 4.268415861 0.411777125 RAS(ph)LSDLTDLEDIEGLTVR ddPTM_HeLa_Curcumin_4h_R1 1 RASLSDLTDLEDIEGLTVR 19 1 J3KSI3;J3KSU7;K7EN88;Q8WZ73-3;Q8WZ73-2;Q8WZ73 J3KSI3 RFFL;hCG_2039718 E3 ubiquitin-protein ligase rififylin 1 0 RAS(0.963)LS(0.037)DLTDLEDIEGLTVR 213.01 5.52E-18 2853500 800.55 491.1 530.52 658.76 849.61 815.8 577.16 484.05 1122 724.48 TRUE FALSE FALSE 737.1856228 533.5484957 550.1815379 656.0342257 839.4789556 646.593884 593.3535563 631.6346167 998.9194071 749.6556261 0.983365691 0.711724794 0.733912371 0.875114123 1.119819456 0.862521218 0.791501505 0.842566366 1.332504382 1 9.550084198 -7.475069509 23.97292948 0.992661411 0.85319417 0.308815588 0.150121381 249.2838957 124999.0336 0.019007603 0.021670059 3.35E-08 7.475069509 -0.139467241 RAS(ph)LSEIGFGK ddPTM_HeLa_Curcumin_4h_R1 2 RASLSEIGFGK 11 1 Q00537-2;Q00537;F5H6Z0 Q00537-2 CDK17 Cyclin-dependent kinase 17 1 0 RAS(0.99)LS(0.01)EIGFGK;RAS(0.985)LS(0.015)EIGFGK ; 129.77 0.004535 88170000 11095.6 9253.9 9564.6 10194.4 10056.7 15062.7 12498.1 9752.1 10890.6 8748.1 TRUE FALSE FALSE 10217.37155 10053.76588 9919.07249 10152.21827 9936.780421 11938.52623 12848.76305 12725.4704 9695.928427 9052.095824 1.128729937 1.110656148 1.095776346 1.121532347 1.097732571 1.318868742 1.419424109 1.405803766 1.071125253 1 13.14403614 -5.168894628 2.136795979 1.072643228 1.417477431 0.932117334 0.036520156 0.079315321 0.693840039 0.007994503 0.026377971 6.78E-06 5.168894628 0.344834203 RAS(ph)PAPSDSSPGEPFVGGPVSSPR ddPTM_HeLa_Curcumin_4h_R1 1 RASPAPSDSSPGEPFVGGPVSSPR 24 1 O60346 O60346 PHLPP1 PH domain leucine-rich repeat-containing protein phosphatase 1 1 0 RAS(0.962)PAPS(0.027)DS(0.007)S(0.004)PGEPFVGGPVSSPR 63.893 0.0014358 6843000 874.43 874.01 717.27 864.43 888.54 598.4 261.3 610.61 889.93 967.08 TRUE FALSE FALSE 805.2179428 949.5555299 743.8526572 860.8532177 877.9447408 474.2850946 268.6313747 796.7821781 792.3069055 1000.685958 0.804665976 0.948904621 0.743342755 0.860263113 0.87734292 0.473959978 0.268447231 0.796235994 0.791763789 1 9.966773574 -5.267836332 9.656884584 0.890945302 0.488264912 0.553252947 0.141000726 0.07816251 99.7454163 0.019556562 0.04581916 5.40E-06 5.267836332 -0.40268039 LSSSSATLLNS(ph)PDRAR ddPTM_HeLa_Curcumin_4h_R1 2 LSSSSATLLNSPDRAR 16 1 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;A0A087WZ40 Q14244-3 MAP7 Ensconsin 1 0 LSSSSATLLNS(1)PDRAR;LSSSSATLLNS(1)PDRAR ; 120.55 0.0086446 78527100 8615.2 6333.9 6645.7 7118.2 5620.2 9745.3 6429.8 2632.4 8740.9 6853.2 TRUE FALSE FALSE 7933.297829 6881.374093 6891.995488 7088.746774 5553.182786 7724.014928 6610.202883 3435.006642 7782.045139 7091.34819 1.118729135 0.970390102 0.971887898 0.999633156 0.78309267 1.089216708 0.932150376 0.484394018 1.097399949 1 12.79184422 -4.271140258 3.168349768 1.023374891 0.410504484 0.738749908 0.09145011 0.129796332 2.028156941 0.013508524 0.193954256 5.36E-05 4.271140258 -0.612870408 down RAS(ph)PNSDDTVLSPQELQK ddPTM_HeLa_Curcumin_4h_R1 1 RASPNSDDTVLSPQELQK 18 1 Q9UH62 Q9UH62 ARMCX3 Armadillo repeat-containing X-linked protein 3 1 0 RAS(0.848)PNS(0.152)DDTVLSPQELQK 118.44 0.00018854 23763000 2671 2189.7 2470.8 2346 2110.5 2986.6 1993.2 1903.4 2689.8 2435.9 TRUE FALSE FALSE 2459.587532 2378.967911 2562.370022 2336.292874 2085.333666 2367.145494 2049.123828 2483.737898 2394.73567 2520.547344 0.975814851 0.943829886 1.016592697 0.926899024 0.827333663 0.939139469 0.8129678 0.985396249 0.950085574 1 11.29952134 -6.038228975 5.987138071 0.9857496 0.887499743 0.385564163 0.050728174 0.115945756 11.69415801 0.006571167 0.011185952 9.16E-07 6.038228975 -0.098249857 GADNDGSGSES(ph)GY(ph)TT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 GADNDGSGSESGYTTPK 17 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 3 0 GADNDGS(0.164)GS(0.342)ES(0.523)GY(0.921)T(0.308)T(0.742)PK 65.477 0.014395 20484000 2860.1 1992.8 1959.2 2200.2 2145.2 3325.9 2172.8 810.12 2592.7 2254.6 TRUE FALSE FALSE 2633.720067 2165.048752 2031.809675 2191.096155 2119.619891 2636.070849 2233.76292 1057.121859 2308.287297 2332.947182 1.128924001 0.92803162 0.870919707 0.93919664 0.908558885 1.129931646 0.957485423 0.453127215 0.989429728 1 11.18793793 -4.269909524 4.000734969 1.023787825 0.406318385 0.758480503 0.087936481 0.08702879 2.895501302 0.014171033 0.153333942 5.37E-05 4.269909524 -0.61746944 down RAS(ph)QEANLLTLAQK ddPTM_HeLa_Curcumin_4h_R1 2 RASQEANLLTLAQK 14 1 A0A0A0MSU2;A0A1C7CYX1;Q6PJG2;H7C1L3 A0A0A0MSU2 ELMSAN1 ELM2 and SANT domain-containing protein 1 1 0 RAS(1)QEANLLTLAQK;RAS(1)QEANLLTLAQK ; 151.11 0.00076279 140556000 9616.7 8607.1 9616.1 8850.2 9676.8 10779.2 7439.1 5254.67 10129.2 8786.5 TRUE FALSE FALSE 8855.528048 9351.059372 9972.481125 8813.580217 9561.41048 8543.472413 7647.821125 6856.794693 9018.052102 9091.830221 0.974009394 1.028512318 1.096861785 0.969395601 1.051648595 0.939686752 0.841175092 0.754171 0.991885229 1 13.15035503 -4.691236917 2.018153606 1.001383092 0.756538807 0.834101751 0.038939646 0.1173624 0.848119526 0.005831846 0.038440999 2.04E-05 4.691236917 -0.244844285 RAS(ph)SLNVLNVGGK ddPTM_HeLa_Curcumin_4h_R1 2 RASSLNVLNVGGK 13 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;H0YJK1 Q07866-6 KLC1 Kinesin light chain 1 1 0 RAS(0.77)S(0.23)LNVLNVGGK;RAS(0.5)S(0.5)LNVLNVGGK ; 136.81 0.00056071 151480000 10724.4 7732.5 8831.1 9631.2 8558 11386.3 7832 8853.6 10465.1 8533.1 TRUE FALSE FALSE 9875.552424 8400.862845 9158.388335 9591.348646 8455.951439 9024.65303 8051.744841 11553.02188 9317.104712 8829.62459 1.11845666 0.951440546 1.03723417 1.086269133 0.957679611 1.022087965 0.911901153 1.308438628 1.055209609 1 13.10813638 -11.5247754 13.05886547 0.527523293 1.045687282 0 0.10644879 0 0 0 0.01295791 2.99E-12 11.5247754 0.518163989 RAS(ph)WAS(ph)ENGETDAEGTQMTPAK ddPTM_HeLa_Curcumin_4h_R1 1 RASWASENGETDAEGTQMTPAK 22 1 Q12789-3;Q12789 Q12789-3 GTF3C1 General transcription factor 3C polypeptide 1 2 0 RAS(0.974)WAS(0.98)ENGET(0.027)DAEGT(0.018)QMT(0.001)PAK 62.67 0.0028391 20127000 3309.7 2690.9 3191.8 2992.5 3009.5 3758.6 3876.4 3452.1 3059.8 3075.6 TRUE FALSE FALSE 3047.733753 2923.489406 3310.090916 2980.117828 2973.613678 2979.023992 3985.161351 4504.629398 2724.147595 3182.476871 0.957660928 0.918620786 1.04009897 0.936414607 0.934370869 0.936070901 1.252220051 1.415447647 0.85598347 1 11.63593431 -4.612529194 3.384270154 0.970648957 1.391581601 0.897890381 0.05282834 0.039346796 0.850323262 0.005657999 0.027665605 2.44E-05 4.612529194 0.420932644 RAS(ph)WASENGETDAEGTQMTPAK ddPTM_HeLa_Curcumin_4h_R1 2 RASWASENGETDAEGTQMTPAK 22 1 Q12789-3;Q12789 Q12789-3 GTF3C1 General transcription factor 3C polypeptide 1 1 0 RAS(0.775)WAS(0.225)ENGETDAEGTQMTPAK;RAS(0.493)WAS(0.18)ENGET(0.321)DAEGT(0.004)QMT(0.001)PAK ; 132.53 9.01E-06 34930000 6076.3 5209.9 5996.1 6516.7 6338.4 7476.8 7667.2 4463.5 5839.7 6629 TRUE FALSE FALSE 5595.354443 5660.220541 6218.320741 6489.735622 6262.81872 5926.027399 7882.320997 5824.400603 5199.09952 6859.357257 0.815725765 0.82518235 0.906545688 0.946114246 0.913032881 0.863933336 1.149134052 0.849117546 0.757957244 1 12.74385768 RASEDTTSGS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 1 RASEDTTSGSPPK 13 1 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 1 0 RAS(0.004)EDT(0.094)T(0.094)S(0.174)GS(0.633)PPK 93.424 0.016405 3123600 801.98 960.3 892.9 893.49 1036 1024.3 716.07 719.32 965.39 826.45 TRUE FALSE FALSE 738.5024368 1043.304053 925.9916595 889.7929751 1023.646377 811.8486338 736.160997 938.6373567 859.4891323 855.169076 0.863574768 1.219997404 1.082817054 1.040487782 1.197010516 0.949342834 0.860836784 1.097604419 1.005051698 1 9.740065874 -7.295521245 24.99456978 0.935576978 1.056722594 0.167606865 0.106310047 732.1459677 536931.2422 0.019175098 0.021928 5.06E-08 7.295521245 0.121145615 IGVAKPLPLSPEEGYVS(ph)AK ddPTM_HeLa_Curcumin_4h_R1 1 IGVAKPLPLSPEEGYVSAK 19 1 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 0 IGVAKPLPLS(0.43)PEEGY(0.046)VS(0.524)AK 69.259 0.004712 11966000 747.57 708.22 697.31 940.08 616.5 1259.3 1222.3 3567.3 975.78 869.45 TRUE FALSE FALSE 688.3990457 769.435381 723.152922 936.190198 609.1486401 998.1069848 1256.594448 4654.953348 868.7393753 899.6633228 0.765174069 0.855248137 0.803803938 1.040600605 0.67708511 1.10942278 1.396738554 5.174105946 0.9656272 1 9.813241399 -4.234782935 2.924937457 0.888443103 6.066553508 0.989809922 0.129192949 0.032199009 0.368685319 0.019472377 0.402593582 5.82E-05 4.234782935 5.178110404 up RASPAPSDSSPGEPFVGGPVS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 RASPAPSDSSPGEPFVGGPVSSPR 24 1 O60346 O60346 PHLPP1 PH domain leucine-rich repeat-containing protein phosphatase 1 1 0 RASPAPSDSSPGEPFVGGPVS(0.749)S(0.251)PR 125.15 4.26E-07 8871600 1536.6 1321.5 1445.4 1737.3 1722 832.36 885.5 613.98 1584.5 1088.2 TRUE FALSE FALSE 1414.976489 1435.724572 1498.967796 1730.111513 1701.466275 659.7191534 910.3447468 801.1796756 1410.684314 1126.014869 1.256623272 1.27504939 1.331214922 1.536490823 1.511051338 0.585888492 0.808466009 0.711517847 1.252811444 1 10.13701016 -5.248301704 24.980856 1.206219107 0.71260828 0.703505473 0.17171177 472.8486449 899104.3094 0.030287518 0.076711948 5.65E-06 5.248301704 -0.493610827 RASS(ph)ASVPAVGASAEGTR ddPTM_HeLa_Curcumin_4h_R1 1 RASSASVPAVGASAEGTR 18 1 A0A2R8YFI4;V9GYZ0;Q9BZ23-3;Q9BZ23-4;Q9BZ23 A0A2R8YFI4 PANK2 "Pantothenate kinase 2, mitochondrial" 1 0 RAS(0.063)S(0.613)AS(0.324)VPAVGASAEGTR 62.765 0.011147 12488000 1171 901.97 1131.9 1285.5 1324.1 1707.1 1379.7 972.66 1319.1 1346.3 TRUE FALSE FALSE 1078.314114 979.9322677 1173.84921 1280.180942 1308.310972 1353.028217 1418.410669 1269.219556 1174.39803 1393.083825 0.774048263 0.703426635 0.842626401 0.91895471 0.939147343 0.971246807 1.018180416 0.911086278 0.843020362 1 10.44406636 -5.850336142 2.43321823 0.870334431 0.968230203 0.322043865 0.078755965 0.447105747 5.386150791 0.016595034 0.033627715 1.41E-06 5.850336142 0.097895772 RASS(ph)LNFLNK ddPTM_HeLa_Curcumin_4h_R1 2 RASSLNFLNK 10 1 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 0 RAS(0.065)S(0.935)LNFLNK;RAS(0.241)S(0.759)LNFLNK ; 88.224 0.010185 99108000 8014.5 5828.4 7074.8 6893.8 6640.4 8134.7 6761.7 7785.9 8179.9 8076.5 TRUE FALSE FALSE 7380.143868 6332.180925 7336.998312 6865.275282 6561.217567 6447.471523 6951.415104 10159.78507 7282.585435 8357.157774 0.883092562 0.75769551 0.877929855 0.821484465 0.785101555 0.771490942 0.831791776 1.215698607 0.871418924 1 13.02879666 -8.64335658 0.892327449 0.99041201 0.857311739 0.003413352 0.129640719 0.732105865 1.176414709 0.051821466 0.024886496 2.27E-09 8.64335658 -0.133100271 SAPTAPTPPPPPPPAT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SAPTAPTPPPPPPPATPR 18 0 A6NHN7;A6NHB5;Q14202-2;Q14202 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 0 SAPTAPT(0.001)PPPPPPPAT(0.999)PR 152.59 0.00018694 10583000 1514.8 1371.4 1343 1456.3 1549.3 1721.1 1134.1 520.39 1750.3 1436 TRUE FALSE FALSE 1394.901982 1489.937705 1392.772761 1450.274216 1530.825609 1364.124459 1165.919794 679.0545154 1558.296469 1485.900893 0.938758425 1.002716744 0.937325476 0.976023518 1.030233992 0.918045386 0.784655154 0.456998524 1.048721672 1 10.53712218 -4.269785946 1.603241633 0.974256406 0.269438345 0.950195058 0.03716379 0.134424425 0.32532529 0.004687879 0.146614866 5.37E-05 4.269785946 -0.704818061 down RASWASENGET(ph)DAEGT(ph)QMTPAK ddPTM_HeLa_Curcumin_4h_R1 1 RASWASENGETDAEGTQMTPAK 22 1 Q12789-3;Q12789 Q12789-3 GTF3C1 General transcription factor 3C polypeptide 1 2 0 RAS(0.287)WAS(0.218)ENGET(0.551)DAEGT(0.875)QMT(0.069)PAK 69.71 0.00091247 20066000 3925.3 3130.6 3854.8 3639.7 3733.4 4563.6 4607.7 4147 3651.8 3712.7 TRUE FALSE FALSE 3614.608363 3401.195114 3997.662279 3624.639886 3688.881643 3617.057918 4736.979661 5411.40121 3251.206676 3841.716049 0.940883792 0.88533225 1.040592857 0.943495001 0.960217152 0.941521412 1.233037424 1.408589584 0.846290209 1 11.90753517 -4.5901554 2.969787478 0.965297357 1.392838316 0.882440003 0.056063911 0.048748809 0.81014431 0.006108072 0.034365944 2.57E-05 4.5901554 0.427540958 RAT(ph)ISSPLELEGTVSR ddPTM_HeLa_Curcumin_4h_R1 2 RATISSPLELEGTVSR 16 1 Q96GS4 Q96GS4 C17orf59 Uncharacterized protein C17orf59 1 0 RAT(0.999)IS(0.001)SPLELEGTVSR;RAT(0.917)IS(0.062)S(0.021)PLELEGTVSR ; 106.19 0.00075635 2662100 752.76 791.1 723.94 746.26 778.27 1070.63 1058 921.63 822.07 841.63 TRUE FALSE FALSE 693.1782517 859.4791589 750.7698532 743.1721739 768.9896386 848.5692695 1087.684633 1202.630744 731.8909777 870.8765799 0.795954637 0.986912702 0.862085249 0.853361074 0.883006452 0.974385222 1.248953822 1.380942802 0.840407234 1 9.766324465 -4.708596662 2.349946842 0.899603551 1.374760743 0.888581829 0.060287491 0.094568323 0.979412715 0.011315991 0.062573617 1.96E-05 4.708596662 0.475157192 DLIT(ph)QAT(ph)LLYT(ph)MADK ddPTM_HeLa_Curcumin_4h_R1 1 DLITQATLLYTMADK 15 0 Q6PD62;H0YCE8 Q6PD62 CTR9 RNA polymerase-associated protein CTR9 homolog 3 0 DLIT(1)QAT(0.933)LLY(0.502)T(0.566)MADK 48.704 0.020337 10652000 4021.8 2916.3 3058 3719.3 3666.7 3885.4 2425 924.71 4465.6 3777.3 TRUE FALSE FALSE 3703.470286 3168.371977 3171.33217 3703.910522 3622.976997 3079.524243 2493.038973 1206.649822 3975.734852 3908.560894 0.947527846 0.81062367 0.811381032 0.94764048 0.926933748 0.787892098 0.637840638 0.308719719 1.017186366 1 11.9324218 -4.269243949 0.989870085 0.949207133 1.76E-15 0.88780628 0.067909964 0.46938617 0.352814142 0.011668211 0.471925306 5.38E-05 4.269243949 -0.949207133 down RAVSEGCAS(ph)EDEVEGEA ddPTM_HeLa_Curcumin_4h_R1 1 RAVSEGCASEDEVEGEA 17 1 Q9BYX2-6;Q9BYX2-5;Q9BYX2-4;Q9BYX2-2;Q9BYX2 Q9BYX2-6 TBC1D2 TBC1 domain family member 2A 1 0 RAVSEGCAS(1)EDEVEGEA 128.82 0.00053667 70878000 2869.9 2773 2834.7 3006.9 2842.2 3654.6 2265.2 2101.1 2979 2566.3 TRUE FALSE FALSE 2642.744387 3012.685764 2939.756476 2994.458245 2808.308621 2896.594764 2328.755416 2741.715718 2652.211153 2655.478734 0.9952045 1.134516999 1.107053293 1.127652881 1.057552669 1.090799458 0.876962555 1.032475117 0.998769495 1 11.37475626 -3.337365821 14.04614349 1.024832153 1.045804174 0 0.076735278 0 0 0.010719512 0 0.000459869 3.337365821 0.020972021 RAVVVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 RAVVVSPK 8 1 G3V5E1;O75909-1;O75909 G3V5E1 CCNK Cyclin-K 1 0 RAVVVS(1)PK 73.9 0.018364 49956000 6169.9 5462.3 6113.8 5643.3 6617.7 6476.2 5170.8 4520.4 5461 5004.5 TRUE FALSE FALSE 5681.545905 5934.436872 6340.382806 5619.94952 6538.78825 5132.963118 5315.878732 5898.649151 4861.941963 5178.406002 1.097161154 1.145996832 1.224388896 1.0852663 1.262702895 0.991224542 1.026547306 1.139085879 0.93888775 1 12.33829237 -8.590281455 0.871738149 1.008431205 1.121322273 0.340510103 0.080479081 0.563927582 0.871748243 0.033073176 0.016343344 2.57E-09 8.590281455 0.112891068 RCAT(ph)PVIIDEILPSK ddPTM_HeLa_Curcumin_4h_R1 1 RCATPVIIDEILPSK 15 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 0 RCAT(1)PVIIDEILPSK 109.28 0.0012068 5920200 3466.3 2715.9 2992.7 2902.8 2733 3263.2 2813.4 898.24 3150.1 2582.4 TRUE FALSE FALSE 3191.938697 2950.650294 3103.612095 2890.788983 2700.41076 2586.375536 2892.336432 1172.109241 2804.541911 2672.138208 1.19452605 1.104228174 1.161471396 1.081826147 1.010580498 0.967904852 1.082405253 0.43864095 1.049549721 1 11.38377891 -4.261319164 9.102754234 1.084302131 0.435939923 0.887220131 0.067680104 0.023996003 41.10783032 0.012039001 0.094244661 5.48E-05 4.261319164 -0.648362208 NIPS(ph)PGQLDPDTR ddPTM_HeLa_Curcumin_4h_R1 1 NIPSPGQLDPDTR 13 0 Q9P2D1 Q9P2D1 CHD7 Chromodomain-helicase-DNA-binding protein 7 1 0 NIPS(0.945)PGQLDPDT(0.055)R 88.706 0.013699 3533200 2064.5 1497.9 1753.3 2343.6 2098.8 2185.6 1516.6 676.79 2025.1 1820.9 TRUE FALSE FALSE 1901.092647 1627.371801 1818.27884 2333.902804 2073.773181 1732.281923 1559.151714 883.1401554 1802.951597 1884.176139 1.008978198 0.863704708 0.965025935 1.238686105 1.100625964 0.91938428 0.827497855 0.468714223 0.956891216 1 10.87971812 -4.268930317 1.622856379 1.012670252 0.276887417 0.750556806 0.095423886 0.378838637 0.944026225 0.014010665 0.435489538 5.38E-05 4.268930317 -0.735782835 down RCQTAEADS(ph)ES(ph)DHEVPEPESEMK ddPTM_HeLa_Curcumin_4h_R1 1 RCQTAEADSESDHEVPEPESEMK 23 1 Q9BPX3 Q9BPX3 NCAPG Condensin complex subunit 3 2 0 RCQT(0.03)AEADS(0.976)ES(0.992)DHEVPEPES(0.002)EMK 57.806 0.0040439 12328000 1781.2 1668.6 1727.5 1740.6 1836.9 2403.5 1452.6 1041.2 2112.4 1664.2 TRUE FALSE FALSE 1640.21614 1812.826349 1791.52267 1733.397858 1814.996167 1904.987007 1493.356047 1358.657087 1880.675005 1722.030826 0.952489419 1.052725841 1.040354587 1.006600946 1.053985875 1.106244428 0.867206338 0.788985346 1.092126213 1 10.74989525 -4.575284026 6.533766617 1.001283767 0.807324748 0.682332586 0.05388571 0.077230729 7.116002565 0.007388442 0.028696178 2.66E-05 4.575284026 -0.193959019 NFSCGS(ph)VEFDEADLESLR ddPTM_HeLa_Curcumin_4h_R1 1 NFSCGSVEFDEADLESLR 18 0 G5E9V3;E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;E9PDY7;A0A1W2PQ63 G5E9V3 PHLDB2 Pleckstrin homology-like domain family B member 2 1 0 NFS(0.002)CGS(0.98)VEFDEADLES(0.018)LR 156.08 5.07E-05 9854200 1870.6 1456.8 1568.2 1757 1597.5 2314.4 1465.7 420.18 1997.8 1414.2 TRUE FALSE FALSE 1722.540036 1582.719301 1626.318872 1749.73 1578.450856 1834.367351 1506.823597 548.2909477 1778.646338 1463.343345 1.177126368 1.081577544 1.111372035 1.195707081 1.078660631 1.253545422 1.029712953 0.374683733 1.215467542 1 10.51505259 -4.268777877 4.237510483 1.104993433 0.322376877 0.894143505 0.077726628 0.050931219 2.079171747 0.011585997 0.11889569 5.39E-05 4.268777877 -0.782616556 down RCS(ph)DPSLNEK ddPTM_HeLa_Curcumin_4h_R1 2 RCSDPSLNEK 10 1 Q13615-3;Q13615-2;Q13615;G5E953 Q13615-3 MTMR3 Myotubularin-related protein 3 1 0 RCS(1)DPSLNEK;RCS(1)DPSLNEK ; 81.703 0.013925 44785000 12708.4 10868.7 11273.8 11492.1 11896.8 13072.1 8631 7093.4 13445.1 11675.5 TRUE FALSE FALSE 11702.51673 11808.142 11691.61695 11444.54874 11754.93843 10360.79911 8873.162631 9256.145006 11970.20617 12081.22276 0.968653336 0.977396265 0.967751128 0.947300531 0.972992442 0.857595238 0.734458987 0.766159618 0.990810815 1 13.56047886 -5.044609484 2.239537122 0.980209747 0.746559766 0.964382916 0.01738601 0.041549901 0.403051068 0.002844349 0.010328639 9.02E-06 5.044609484 -0.23364998 RDATRSS(ph)T(ph)SRY(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 RDATRSSTSRYK 12 3 Q86VF2-4;Q86VF2-3;Q86VF2-2;Q86VF2;Q86VF2-5 Q86VF2-4 IGFN1 Immunoglobulin-like and fibronectin type III domain-containing protein 1 3 0 RDAT(0.406)RS(0.462)S(0.498)T(0.574)S(0.065)RY(0.996)K 64.878 0.0075655 0 195 208.28 203.37 159.22 201.73 322.56 197.55 171.9 119.92 179.74 TRUE FALSE FALSE 179.5655442 226.2827951 210.9070711 158.5611898 199.3245015 255.65742 203.0927213 224.3115187 106.765076 185.9859516 0.965479073 1.216666061 1.133994634 0.852543907 1.071718051 1.374606081 1.091978827 1.206067 0.574049142 1 7.539049842 -5.458596844 0.451927432 0.985596815 1.259572822 0.260197258 0.180816715 2.005935219 0.539359682 0.035222832 0.248378883 3.48E-06 5.458596844 0.273976006 RDDFFYEDR ddPTM_HeLa_Curcumin_4h_R1 1 RDDFFYEDR 9 1 G3V1T9;J3KPD3;Q9Y580 G3V1T9 RBM7 RNA-binding protein 7 0 0 128.91 0.00059706 0 1164 996.14 874.62 938.93 993.61 1189.6 892.65 940.06 1025.2 959.39 FALSE FALSE TRUE 1071.868172 1082.241903 907.0341866 935.0449564 981.7618497 942.8635504 917.6953566 1226.679966 912.7381249 992.7287311 1.0797191 1.090168813 0.913677783 0.941893719 0.988952791 0.94976958 0.924417041 1.235664818 0.9194235 1 9.955255737 -6.776608175 24.9911298 1.042636248 0.984916362 0.001725422 0.097645358 456.2620557 751706.6935 0.014109386 0.018583497 1.67E-07 6.776608175 -0.057719887 RDDGSWEVIEGYR ddPTM_HeLa_Curcumin_4h_R1 1 RDDGSWEVIEGYR 13 1 P49448;P00367 P49448 GLUD2;GLUD1 "Glutamate dehydrogenase 2, mitochondrial;Glutamate dehydrogenase 1, mitochondrial" 0 0 131.08 0.0023149 6396900 1377.7 1115 1001.6 1187.7 1105.1 1628.3 931.22 1052.1 1348.5 911.98 FALSE FALSE TRUE 1268.653591 1211.375632 1038.720177 1182.785612 1091.922404 1290.572225 957.3475269 1372.880447 1200.572924 943.6712371 1.344380904 1.283683961 1.100722515 1.253387372 1.157100441 1.367607886 1.014492642 1.454829174 1.272236428 1 9.882140521 -9.462084458 1.182503701 0.999195246 1.247480118 0 0.148363025 0.396224368 0.986043812 0.080442682 0.01961454 3.45E-10 9.462084458 0.248284872 RDDIEDGDSMISSAT(ph)SDTGSAK ddPTM_HeLa_Curcumin_4h_R1 2 RDDIEDGDSMISSATSDTGSAK 22 1 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-7;Q86U86-3;Q86U86-2;Q86U86-4;Q86U86-9;H0Y5B5;Q86U86-6 Q86U86-8 PBRM1 Protein polybromo-1 1 0 RDDIEDGDSMISS(0.013)AT(0.509)S(0.021)DT(0.171)GS(0.286)AK;RDDIEDGDSMIS(0.001)S(0.008)AT(0.934)S(0.035)DT(0.02)GS(0.002)AK ; 168.77 6.10E-09 15604900 4000.8 3298 3722.2 3290.4 3555.2 4684.7 3618.4 1577.08 4330.8 3895.6 TRUE FALSE FALSE 3684.132458 3583.064424 3860.148006 3276.785197 3512.806562 3713.040413 3719.922566 2057.924432 3855.722075 4030.97181 0.913956394 0.888883523 0.957622179 0.812902037 0.871454013 0.921127854 0.922835172 0.510528113 0.956524197 1 11.97691198 -4.260990607 5.852684208 0.934225324 0.497936547 0.844881763 0.051642356 0.043690774 6.696138663 0.008621331 0.075506575 5.48E-05 4.260990607 -0.436288777 RDDNSAANNSANEK(ac)ER ddPTM_HeLa_Curcumin_4h_R1 2 RDDNSAANNSANEKER 16 2 H0Y3P2;D3DQV9;P78344-2;P78344;H0YCH5;H0YEC5;H0YD77;H0YD99;H0YEN8;H0YDC0;H0YCF8;H0YEI7 H0Y3P2 EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 0 1 ; RDDNSAANNSANEK(1)ER;RDDNSAANNSANEK(1)ER 69.069 0.010135 519340 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 RDEDMLYS(ph)PELAQR ddPTM_HeLa_Curcumin_4h_R1 4 RDEDMLYSPELAQR 14 1 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 0 RDEDMLYS(1)PELAQR;RDEDMLYS(1)PELAQR;RDEDMLYS(1)PELAQR;RDEDMLY(0.002)S(0.998)PELAQR ;;; 111.62 0.0012773 22204700 4824.6 4871.9 4871.83 4415.8 5551.5 5604.3 4980.1 3481.77 5463.2 5415.5 TRUE FALSE FALSE 4442.727819 5293.005327 5052.384305 4397.52859 5485.301988 4441.905007 5119.828203 4543.345645 4863.900628 5603.688222 0.792822092 0.944557427 0.901617668 0.784756113 0.978873515 0.792675258 0.913653294 0.810777735 0.867982021 1 12.45216097 -9.528107021 1.260446906 1.000680741 0.860136572 0.006274204 0.076674877 0.369598122 1.04316885 0.044938823 0.010534354 2.96E-10 9.528107021 -0.140544169 RDEFEFLEK ddPTM_HeLa_Curcumin_4h_R1 1 RDEFEFLEK 9 1 A0A3B3IUA7;Q14258 A0A3B3IUA7 TRIM25 E3 ubiquitin/ISG15 ligase TRIM25 0 0 123.96 0.0076349 7552200 6401.5 5225.5 5661 5934.4 5754.2 5999.5 5246 4211.2 4603.6 4399.3 FALSE FALSE TRUE 5894.81452 5677.168936 5870.80164 5909.845025 5685.584923 4755.136072 5393.188641 5495.175494 4098.596598 4552.175348 1.29494452 1.247133184 1.289669486 1.298246349 1.248981968 1.044585436 1.184749758 1.20715374 0.90036 1 12.15234042 -9.371976641 1.072435457 0.99878512 1.230259697 0.64551487 0.079317059 0.315772121 0.644348822 0.055315881 0.013989324 4.25E-10 9.371976641 0.231474576 RDGT(ph)GHYLCNACGLYSKMNGLS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 RDGTGHYLCNACGLYSKMNGLSR 23 2 Q92908-2;Q92908 Q92908-2 GATA6 Transcription factor GATA-6 2 0 RDGT(0.993)GHY(0.019)LCNACGLY(0.091)S(0.099)KMNGLS(0.799)R 51.819 0.00889 3319800 669.25 483.32 535.27 506.13 460.77 448.98 343.73 495.98 649.53 456.97 TRUE FALSE FALSE 616.2781563 525.0960272 555.1075771 504.0357682 455.2756187 355.856487 353.3741387 647.2020188 578.278184 472.8496735 1.303327867 1.110492524 1.173962061 1.065953508 0.962833738 0.752578477 0.747328715 1.368726796 1.222964118 1 8.88523779 -5.870041312 2.900763746 1.145463443 0.925720468 0.218825913 0.17694321 0.306034395 5.194597926 0.028203788 0.055114684 1.35E-06 5.870041312 -0.219742975 RDHALLEEQSK ddPTM_HeLa_Curcumin_4h_R1 2 RDHALLEEQSK 11 1 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 0 ; ; 140.45 0.0019747 19477100 7342.8 5288 6650.7 5738.6 7985.5 8543.8 7125.1 6507.8 6349.9 5937.2 FALSE FALSE TRUE 6761.609632 5745.071157 6897.180793 5714.855194 7890.278128 6771.719572 7325.01113 8491.998262 5653.331857 6143.517258 1.100608877 0.935143651 1.12267623 0.930225302 1.284325867 1.102254505 1.192315545 1.382269782 0.920210951 1 12.58484914 -1 0.452324417 1.036713239 8.747851249 0.574802827 0.096921911 39.95385399 0.429061798 0.018126241 287.3600346 0.1 1 7.711138011 RDLFAFQES(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 1 RDLFAFQESPPR 12 1 E7EX48;P51957-3;P51957;P51957-2 E7EX48 NEK4 Serine/threonine-protein kinase Nek4 1 0 RDLFAFQES(1)PPR 83.292 0.010093 3881500 1570.1 1252.6 1253 1552.1 1466.8 1972.6 1235.2 752 1691.4 1500.5 TRUE FALSE FALSE 1445.824928 1360.869163 1299.437282 1545.677821 1449.309368 1563.460524 1269.856388 981.2813382 1505.857652 1552.642263 0.931202868 0.876485971 0.836919948 0.995514458 0.933447068 1.006967646 0.817867977 0.63200736 0.969867746 1 10.60050975 -4.427090161 2.781605606 0.952581027 0.620946661 0.762014541 0.053581494 0.121889271 1.526799687 0.008260714 0.075626967 3.74E-05 4.427090161 -0.331634366 RDNYVPEVSALDQEIIEVDPDTK ddPTM_HeLa_Curcumin_4h_R1 2 RDNYVPEVSALDQEIIEVDPDTK 23 1 H0YN88;A0A075B716;H3BNC9;P08708 H0YN88 RPS17 40S ribosomal protein S17 0 0 ; ; 118.05 6.87E-06 5075500 3801.2 3237.5 3124.96 3523.26 4023.3 4125.6 3435.94 3022.43 2918.23 2998.18 FALSE FALSE TRUE 3500.331009 3517.335074 3240.773767 3508.681684 3975.324775 3269.904055 3532.343229 3943.954993 2598.10747 3102.366532 1.128277711 1.133758709 1.044613437 1.130969422 1.281384625 1.054003136 1.138596356 1.27127306 0.837459869 1 11.59915343 -13.52287874 0.104367338 0.501211682 1.250800455 0.505973035 0.086282116 79.17840048 0.612610821 8.531541627 0.507599658 3.00E-14 13.52287874 0.749588773 RDPSSNDINGGMEPT(ph)PSTVSTPSPSADLLGLR ddPTM_HeLa_Curcumin_4h_R1 1 RDPSSNDINGGMEPTPSTVSTPSPSADLLGLR 32 1 O95782-2;O95782 O95782-2 AP2A1 AP-2 complex subunit alpha-1 1 0 RDPSSNDINGGMEPT(0.601)PS(0.034)T(0.034)VS(0.008)T(0.058)PS(0.234)PS(0.031)ADLLGLR 95.713 8.91E-09 33365000 813.36 752.22 746.95 697.3 782.96 1216.3 963.77 432.03 830.66 634.43 TRUE FALSE FALSE 748.9816977 817.238545 774.6326241 694.4147574 773.6237134 964.0256695 990.8107923 563.7539582 739.5386762 656.4763953 1.140911849 1.244886413 1.179985495 1.057790901 1.178448637 1.468484894 1.509286243 0.858757394 1.126527445 1 9.358599327 -8.030140997 0.335198582 0.969209522 1.271962252 0.075728975 0.180029835 1.779266877 0.534718053 0.216302105 0.11979585 9.33E-09 8.030140997 0.30275273 RDPSSNDINGGMEPTPSTVSTPS(ph)PSADLLGLR ddPTM_HeLa_Curcumin_4h_R1 2 RDPSSNDINGGMEPTPSTVSTPSPSADLLGLR 32 1 O95782-2;O95782 O95782-2 AP2A1 AP-2 complex subunit alpha-1 1 0 RDPSSNDINGGMEPT(0.001)PS(0.01)T(0.022)VS(0.045)T(0.111)PS(0.72)PS(0.092)ADLLGLR;RDPSSNDINGGMEPT(0.055)PS(0.165)T(0.165)VS(0.033)T(0.091)PS(0.48)PS(0.011)ADLLGLR ; 130.79 4.04E-13 16037000 1108.46 922.2 1081.96 1045.64 1130.21 1311.21 1078.14 802.98 1176.91 854.53 TRUE FALSE FALSE 1020.724221 1001.910859 1122.058389 1041.313419 1116.732984 1039.250266 1108.389707 1047.804906 1047.805917 884.2248539 1.154371783 1.133095111 1.268974045 1.177656808 1.262951362 1.175323518 1.253515666 1.184998251 1.184999396 1 9.788269476 -8.576338942 0.412926089 0.971953828 1.227321739 0.14974762 0.068715529 0.403430234 0.134109948 0.044045534 0.01420674 2.65E-09 8.576338942 0.25536791 RDQALTEEHAR ddPTM_HeLa_Curcumin_4h_R1 6 RDQALTEEHAR 11 1 P12814-4;P12814-3;P12814;P12814-2;H9KV75;H0YJ11 P12814-4 ACTN1 Alpha-actinin-1 0 0 ;;;;; ;;;;; 135.8 3.52E-05 55790800 11958.1 6394.94 11193.8 9309.8 12795.2 16258 12204.6 13481.6 9127.5 8593.3 FALSE FALSE TRUE 11011.60377 6947.690118 11608.65208 9271.278514 12642.6256 12885.90753 12547.02823 17592.07778 8126.236086 8891.916535 1.238383618 0.781349003 1.305528682 1.042663691 1.421811096 1.449170995 1.411060054 1.978434875 0.913890279 1 13.11827869 -1 0.438912675 1.084253695 18.91317274 0.737360432 0.167393001 27.87387037 0.307631335 0.034810017 446.1665235 0.1 1 17.82891905 RDS(ph)DGVDGFEAEGK ddPTM_HeLa_Curcumin_4h_R1 4 RDSDGVDGFEAEGK 14 1 Q96KR1 Q96KR1 ZFR Zinc finger RNA-binding protein 1 0 RDS(1)DGVDGFEAEGK;RDS(1)DGVDGFEAEGK;RDS(1)DGVDGFEAEGK;RDS(1)DGVDGFEAEGK ;;; 162.92 0.00011328 120562000 18453.7 16039.3 18362.9 17450.9 19611.4 20499.4 22835.1 22834.4 19057.7 16145.2 TRUE FALSE FALSE 16993.07017 17425.66562 19043.44523 17378.6928 19377.54686 16247.59336 23475.79145 29796.50344 16967.11799 16706.2445 1.01716877 1.043063007 1.139899828 1.040251315 1.159898436 0.972546126 1.405210576 1.783554853 1.015615328 1 14.02809984 -4.473090506 2.322446984 1.030317758 1.82469808 0.928603148 0.064311983 0.068070969 0.579460849 0.00926223 0.090192623 3.36E-05 4.473090506 0.794380321 RDS(ph)DGVDGFEAEGKK ddPTM_HeLa_Curcumin_4h_R1 1 RDSDGVDGFEAEGKK 15 2 Q96KR1 Q96KR1 ZFR Zinc finger RNA-binding protein 1 0 RDS(1)DGVDGFEAEGKK 89.604 0.005779 41170000 3999 3253.6 3797.9 3698.7 3805.2 4246.4 5502.7 4944.4 4468.1 3345.1 TRUE FALSE FALSE 3682.47493 3534.826686 3938.653515 3683.395759 3759.825475 3365.648773 5657.090952 6451.924799 3977.960609 3461.341976 1.06388648 1.021230121 1.137897828 1.064152512 1.086233461 0.972353728 1.63436349 1.863995191 1.149253855 1 11.75711577 -4.664140505 3.98276754 1.040788295 1.814982225 0.951050335 0.062955756 0.025554702 0.732778008 0.007704325 0.032679202 2.17E-05 4.664140505 0.774193931 DGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVS(ph)SPVQEK ddPTM_HeLa_Curcumin_4h_R1 2 DGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEK 41 1 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 DGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVS(0.782)S(0.218)PVQEK;DGAEQQGPEAT(0.004)VEEAEAAAFGS(0.088)EKPQS(0.088)MFEPPQVS(0.538)S(0.282)PVQEK ; 93.64 1.46E-14 21228200 7149.3 7097 7704.1 7271.4 7423.5 9071.3 9598.6 11983.7 7189 6678.7 TRUE FALSE FALSE 6583.425361 7710.433056 7989.620723 7241.312873 7334.979611 7189.810125 9867.910883 15637.47496 6400.384686 6910.784328 0.952630707 1.115710271 1.156109111 1.047827935 1.061381641 1.040375417 1.427900281 2.262764141 0.92614447 1 12.75463374 -4.23347975 1.701062722 1.010156158 2.766721841 0.96609361 0.069740704 0.133251202 0.351088848 0.011067446 0.38828997 5.84E-05 4.23347975 1.756565683 up S(ph)RSPSS(ph)PELNNK ddPTM_HeLa_Curcumin_4h_R1 1 SRSPSSPELNNK 12 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(0.955)RS(0.045)PS(0.022)S(0.978)PELNNK 95.822 0.0084786 33954000 2893.2 2258.3 2343.6 2803.4 2609.9 3963.8 4151.6 4719.5 2756.7 2345.1 TRUE FALSE FALSE 2664.200167 2453.497389 2430.455878 2791.800274 2578.778647 3141.663199 4268.082723 6158.453824 2454.296907 2426.59205 1.097918444 1.011087706 1.001592285 1.150502522 1.062716185 1.294681237 1.758879381 2.537902415 1.011417188 1 11.24471587 -4.233452653 1.154893778 1.044145877 3.339319158 0.990998469 0.044579301 0.113358981 0.116895931 0.007360101 0.318190915 5.84E-05 4.233452653 2.295173281 up ITS(ph)PLMEPSSIEK ddPTM_HeLa_Curcumin_4h_R1 1 ITSPLMEPSSIEK 13 0 P28066 P28066 PSMA5 Proteasome subunit alpha type-5 1 0 IT(0.027)S(0.972)PLMEPS(0.001)SIEK 126.5 0.0022241 105240000 3802.7 3268.6 3389.8 3031.4 3233.5 5095.9 5504.8 14999 3508 3346.9 TRUE FALSE FALSE 3501.712282 3551.123219 3515.42897 3018.85687 3194.942624 4038.952897 5659.249873 19572.12605 3123.181177 3463.204526 1.011119111 1.025386515 1.015079804 0.871694654 0.9225394 1.166247291 1.634107899 5.651449664 0.901818288 1 11.75789188 -4.233150419 2.774708486 1.002346896 6.711628002 0.996390672 0.083668588 0.020818914 0.203432496 0.012543824 0.277778644 5.85E-05 4.233150419 5.709281106 up RDS(ph)FDNCSLGESSK ddPTM_HeLa_Curcumin_4h_R1 1 RDSFDNCSLGESSK 14 1 Q5UIP0-2;Q5UIP0 Q5UIP0-2 RIF1 Telomere-associated protein RIF1 1 0 RDS(0.999)FDNCS(0.001)LGESSK 206.81 5.37E-09 27835000 3592.7 2456 2447.8 3021.8 2449.2 6081.8 6311.8 2285.9 3332.2 2333.8 TRUE FALSE FALSE 3308.334004 2668.285696 2538.517621 3009.296592 2419.99489 4820.366124 6488.892121 2982.860387 2966.665997 2414.899376 1.369967642 1.104926244 1.051189812 1.246137467 1.002110031 1.996093987 2.687023809 1.235190342 1.228484311 1 11.23774736 -5.252133032 22.03014564 1.159130032 2.044195415 0.54514167 0.345171111 67.25889483 159213.0274 0.045243076 0.113209772 5.60E-06 5.252133032 0.885065383 RDS(ph)FIGTPYWMAPEVVMCETSK ddPTM_HeLa_Curcumin_4h_R1 2 RDSFIGTPYWMAPEVVMCETSK 22 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 0 RDS(0.979)FIGT(0.02)PY(0.001)WMAPEVVMCETSK;RDS(0.797)FIGT(0.109)PY(0.094)WMAPEVVMCETSK ; 104.39 3.06E-05 73820000 1219.23 1180.4 1234.49 1098.59 850.98 2376 1753.01 1720.03 1456.52 1020.3 TRUE FALSE FALSE 1122.726659 1282.428516 1280.241285 1094.044326 840.8326193 1883.190817 1802.194743 2244.459229 1296.7434 1055.755349 1.063434497 1.214702362 1.212630641 1.036266903 0.796427525 1.783737888 1.707019286 2.125927404 1.228261264 1 10.04405984 -5.18949921 6.066947578 1.046236397 1.868246853 0.839723148 0.158536283 0.058270731 3.860506976 0.020540895 0.053096459 6.46E-06 5.18949921 0.822010456 TDSVIIADQTPT(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 TDSVIIADQTPTPTR 15 0 K7ELQ4;P17544-4;P17544-2;P17544;P17544-3;P17544-1;K7ESA4;P17544-5 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 0 TDSVIIADQT(0.002)PT(0.967)PT(0.032)R 149.6 0.0012982 10085000 1590 1339.8 1299.1 1406 1508.2 1863.2 2127.9 5195.1 1797 1165.5 TRUE FALSE FALSE 1464.149822 1455.606342 1347.245789 1400.182345 1490.2157 1476.751317 2187.603147 6779.062075 1599.873596 1206.001038 1.214053534 1.206969394 1.117118266 1.161012553 1.235667013 1.224502526 1.813931396 5.621107992 1.326593879 1 10.23601543 -4.232681961 2.660705792 1.132970088 6.711478868 0.994540064 0.097939007 0.028529986 0.24682776 0.015582009 0.361987125 5.85E-05 4.232681961 5.57850878 up RDS(ph)IVAELDR ddPTM_HeLa_Curcumin_4h_R1 2 RDSIVAELDR 10 1 M0QXB4;O14579-3;O14579 M0QXB4 COPE Coatomer subunit epsilon 1 0 RDS(1)IVAELDR;RDS(1)IVAELDR ; 106.54 0.0042627 11913400 1329.8 1035.16 1371.06 1338.75 1498.96 1389.79 1006.89 882.53 926.57 1295.72 TRUE FALSE FALSE 1224.544927 1124.634618 1421.87269 1333.210607 1481.085881 1101.531888 1035.140623 1151.609334 824.9275892 1340.746174 0.913330913 0.838812476 1.060508482 0.994379573 1.104672838 0.821581228 0.772063082 0.858931658 0.61527499 1 10.38882042 -5.109894557 10.41474949 0.967836409 0.810867287 0.096705022 0.132961306 0.288576635 25.45023706 0.010666777 0.027237344 7.76E-06 5.109894557 -0.156969121 RDS(ph)LAS(ph)HY(ph)SGVSQNIR ddPTM_HeLa_Curcumin_4h_R1 1 RDSLASHYSGVSQNIR 16 1 G3XAL8;Q86YA3-3;Q86YA3-6;Q86YA3-5;Q86YA3-4;Q86YA3 G3XAL8 ZGRF1 Protein ZGRF1 3 0 RDS(0.82)LAS(0.787)HY(0.77)S(0.296)GVS(0.328)QNIR 43.628 0.0096927 0 594.94 625.39 611.75 652.23 708.76 749.09 597.01 337.44 729.11 903.47 TRUE FALSE FALSE 547.8498712 679.4459249 634.4219932 649.5312451 700.3084999 593.72029 613.7604938 440.3239026 649.1284571 934.8655153 0.586019981 0.72678467 0.678623805 0.694785757 0.749100794 0.63508631 0.656522766 0.471002401 0.694354906 1 9.868615031 -9.359037794 0.848398011 1.023263201 0.651837282 0.131751714 0.119335469 0.280388457 0.323973676 0.071084715 0.014499702 4.37E-10 9.359037794 -0.371425919 RDS(ph)LEEGELR ddPTM_HeLa_Curcumin_4h_R1 1 RDSLEEGELR 10 1 Q5QPR4;Q5QPR3;Q9UQ88-4;Q9UQ88-3;Q9UQ88-2;Q9UQ88;J3KS35;E7ESP2;E9PFJ2;A0A0D9SEI3;A0A0D9SER5;A0A0D9SEN2;P21127-6;P21127-9;P21127-8;P21127-3;P21127-2;P21127;A0A087WYI9;A0A087X1I0 Q5QPR4;A0A0D9SEI3 CDK11A;CDK11B Cyclin-dependent kinase 11A;Cyclin-dependent kinase 11B 1 0 RDS(1)LEEGELR 92.039 0.008371 21156000 1245.7 1018.6 1266.5 1139.4 1085.1 1312.4 1196.5 867.69 1163.5 1154.2 TRUE FALSE FALSE 1147.101531 1106.643245 1313.437604 1134.685465 1072.160891 1040.193446 1230.07057 1132.244687 1035.866961 1194.308364 0.960473497 0.926597584 1.099747472 0.950077466 0.897725348 0.870958856 1.029943863 0.948033792 0.867336269 1 10.22195967 -6.017250703 24.85920562 0.985738708 0.936793183 0.03178138 0.067838321 1028.370333 1481939.097 0.00844595 0.014224446 9.61E-07 6.017250703 -0.048945525 RDS(ph)LGAYASQDANEQGQDLGK ddPTM_HeLa_Curcumin_4h_R1 1 RDSLGAYASQDANEQGQDLGK 21 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 RDS(0.978)LGAY(0.021)ASQDANEQGQDLGK 120.31 6.46E-06 11927000 1844 1753.4 1968.6 1966.3 2474.1 2624.5 2135.9 877.51 1645.5 1927.7 TRUE FALSE FALSE 1698.045454 1904.956083 2041.558048 1958.163972 2444.597973 2080.149116 2195.827606 1145.058759 1464.992767 1994.687432 0.851283979 0.955014832 1.023497725 0.981689633 1.225554408 1.04284465 1.100837941 0.574054231 0.734447284 1 10.96194698 -6.906781716 5.100613962 0.928533906 1.008557401 0.058727678 0.171854147 0.544108527 23.56821534 0.025695877 0.033968527 1.24E-07 6.906781716 0.080023494 RDS(ph)LGAYASQDANEQGQDLGKR ddPTM_HeLa_Curcumin_4h_R1 2 RDSLGAYASQDANEQGQDLGKR 22 2 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 RDS(1)LGAYASQDANEQGQDLGKR;RDS(1)LGAYASQDANEQGQDLGKR ; 140.04 2.13E-05 39702000 1887.92 1678.42 1990.7 2052.43 2120.18 2249.45 2148.03 1034.8 1966.77 1605.6 TRUE FALSE FALSE 1738.48914 1823.495146 2064.477093 2043.937588 2094.898238 1782.888713 2208.297941 1350.305756 1751.020252 1661.39448 1.046403585 1.097569041 1.242617041 1.230254231 1.26092765 1.073127866 1.329183386 0.812754449 1.053946111 1 10.69817895 -7.136957859 2.680192321 1.02064193 1.169860791 0.138501664 0.135081503 0.307862396 4.260045702 0.02120178 0.026291427 7.30E-08 7.136957859 0.149218861 RDS(ph)LGTYSSR ddPTM_HeLa_Curcumin_4h_R1 1 RDSLGTYSSR 10 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 RDS(0.987)LGT(0.012)YS(0.001)SR 71.976 0.019568 37742000 1208.6 1072.2 1114.4 1017.9 1226.2 1316.7 1078.7 520.82 890.35 1055.1 TRUE FALSE FALSE 1112.938035 1164.87619 1155.700644 1013.6882 1211.578366 1043.601578 1108.965419 679.6156204 792.6808325 1091.764646 1.019393729 1.066966396 1.05856207 0.928486009 1.109743176 0.955885118 1.015755019 0.62249279 0.726054681 1 10.09244617 -4.261329927 23.72492039 1.014582061 0.622492571 0.509927456 0.103960124 1.053946495 227801.8406 0.006136183 0.047357728 5.48E-05 4.261329927 -0.39208949 LAST(ph)SDIEEKENR ddPTM_HeLa_Curcumin_4h_R1 2 LASTSDIEEKENR 13 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 LAS(0.094)T(0.687)S(0.219)DIEEKENR;LAS(0.004)T(0.913)S(0.083)DIEEKENR ; 203.85 6.49E-08 72886000 7181.5 5878.5 6827 7016.3 6567.2 8841.1 8027.2 12335 7544.4 6732.4 TRUE FALSE FALSE 6613.076697 6386.611346 7080.014626 6987.26841 6488.890429 7007.3562 8252.421628 16095.88472 6716.798195 6966.350399 0.949288554 0.91678009 1.01631618 1.003002722 0.931461965 1.005886267 1.184611907 2.310518965 0.964177483 1 12.76618733 -4.232580841 2.62034635 0.97478549 2.642085492 0.993264256 0.03285904 0.032384226 0.268192162 0.005146077 0.121581316 5.85E-05 4.232580841 1.667300002 up RDS(ph)PLQGSGQQNSQAGQR ddPTM_HeLa_Curcumin_4h_R1 2 RDSPLQGSGQQNSQAGQR 18 1 O95819-3;E7EX83;G5E948;C9J840;H7C360;E7ENQ1;H7C0P6;G3XAA2;A0A0D9SG62;A0A0D9SEY1;O95819-4;O95819-2;O95819;O95819-5;O95819-6;E7EN19 O95819-3 MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 1 0 RDS(1)PLQGSGQQNSQAGQR;RDS(1)PLQGSGQQNSQAGQR ; 143.14 0.00011419 17005100 2676.3 2338.66 2169.21 2325.89 2415.79 2510.5 1973.77 1212.38 2388.05 2034.79 TRUE FALSE FALSE 2464.468031 2540.80335 2249.602831 2316.266083 2386.983282 1989.794001 2029.148674 1582.029081 2126.08689 2105.498801 1.170491301 1.206746519 1.068441753 1.100103255 1.133690164 0.945046371 0.963737749 0.751379711 1.009778248 1 11.03994634 -4.20616189 0.997072932 1.095259621 0.558776844 0.701784808 0.068734339 1.033730947 0.732626449 0.012447696 0.607486804 6.22E-05 4.20616189 -0.536482777 RDS(ph)PTYDPYK ddPTM_HeLa_Curcumin_4h_R1 1 RDSPTYDPYK 10 1 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 0 RDS(0.969)PT(0.029)Y(0.002)DPYK 86.738 0.011038 15972000 5947.4 5376.7 6005.5 6115.3 6107.6 6768.2 5938 4541.6 5888.1 5093.8 TRUE FALSE FALSE 5476.657014 5841.43799 6228.069113 6089.996509 6034.770859 5364.399027 6104.604299 5926.312933 5242.190161 5270.809171 1.039054315 1.10826209 1.181615367 1.155419654 1.144942012 1.01775626 1.158191105 1.12436492 0.994570282 1 12.36380875 -7.314214019 2.487774341 1.015868104 1.129454221 0.619063249 0.042231693 0.147621681 1.733389134 0.00778945 0.009049996 4.85E-08 7.314214019 0.113586117 RDS(ph)PTYDPYKR ddPTM_HeLa_Curcumin_4h_R1 1 RDSPTYDPYKR 11 2 F5H0Q6;A0A0A0MQS2;Q8N2M8-3;Q8N2M8;Q8N2M8-4 F5H0Q6 CLASRP CLK4-associating serine/arginine rich protein 1 0 RDS(0.985)PT(0.013)Y(0.002)DPYKR 58.592 0.016003 16297000 3109.1 2659.8 2746.8 2673.6 2931.1 3269.2 2528.2 2665.6 3018.7 2383.4 TRUE FALSE FALSE 2863.011454 2889.70126 2848.598824 2662.537352 2896.148547 2591.131069 2599.134488 3478.329169 2687.556162 2466.222973 1.160889135 1.171711274 1.155045126 1.079601229 1.174325509 1.050647528 1.053892741 1.410387142 1.089745815 1 11.26808753 -9.224507492 0.776662313 0.99123814 1.149537771 0.139266235 0.100283075 0.813314871 0.808439061 0.08077478 0.018284699 5.96E-10 9.224507492 0.158299631 RDS(ph)QDGSSYR ddPTM_HeLa_Curcumin_4h_R1 1 RDSQDGSSYR 10 1 C9J9W2;Q14847;Q14847-2;Q14847-3;J3KSN1 C9J9W2 LASP1 LIM and SH3 domain protein 1 1 0 RDS(1)QDGSSYR 125.53 0.0016916 8263200 926.22 1281.4 1116.4 909.98 1122.3 1432.7 952.22 671.53 662.33 1288.1 TRUE FALSE FALSE 852.9087097 1392.158506 1157.774766 906.2147439 1108.917305 1135.54187 978.9367304 876.2764057 589.6740561 1332.861379 0.639908038 1.044488593 0.868638543 0.67990172 0.831982472 0.851957966 0.734462522 0.657440015 0.442412141 1 10.38031103 -9.602826261 1.390912635 1.000411289 0.775830661 0 0.207916074 0.418204327 1.447573466 0.087601214 0.02006434 2.50E-10 9.602826261 -0.224580628 SSS(ph)VLSLEGSEK ddPTM_HeLa_Curcumin_4h_R1 2 SSSVLSLEGSEK 12 0 A1L390-3;A1L390;A0A0U1RR71;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 0 SS(0.012)S(0.988)VLSLEGSEK;S(0.001)S(0.076)S(0.89)VLS(0.034)LEGSEK ; 180.61 9.47E-05 22053200 3824.7 2983 3818.6 3470.4 3941.4 4615 5203.2 9639.1 3743.6 3578 TRUE FALSE FALSE 3521.970959 3240.837228 3960.120675 3456.040404 3894.401379 3657.796978 5349.187788 12578.01722 3332.936446 3702.335234 0.951283646 0.875349482 1.069627796 0.933475816 1.051877027 0.987970226 1.444814543 3.397319914 0.900225462 1 11.85421982 -4.232094632 2.391792143 0.978063553 4.076681601 0.99296347 0.061084351 0.031140771 0.199699357 0.007845159 0.20445864 5.86E-05 4.232094632 3.098618049 up RDS(ph)SDDWEIPDGQITVGQR ddPTM_HeLa_Curcumin_4h_R1 5 RDSSDDWEIPDGQITVGQR 19 1 H7C560;A0A2U3TZI2;A0A2R8Y8E0;P15056;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y679 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 0 RDS(0.862)S(0.138)DDWEIPDGQITVGQR;RDS(0.768)S(0.232)DDWEIPDGQITVGQR;RDS(0.606)S(0.394)DDWEIPDGQITVGQR;RDS(0.992)S(0.008)DDWEIPDGQITVGQR;RDS(0.819)S(0.181)DDWEIPDGQITVGQR ;;;; 213.01 5.52E-18 109252100 6137.6 4348.24 4900.57 5759.74 4921.19 6827.56 4744.94 5627.04 6156.3 4902.3 TRUE FALSE FALSE 5651.802484 4724.08249 5082.189435 5735.907722 4862.508023 5411.447094 4878.070246 7342.698592 5480.969292 5072.65456 1.114170582 0.931284091 1.001879662 1.130750705 0.95857267 1.066788016 0.961640535 1.447506134 1.080493305 1 12.3085252 -4.254809136 24.82928656 1.038284877 1.447506339 0.784446533 0.06585681 249.5868522 934638.8535 0.00928867 0.119717131 5.56E-05 4.254809136 0.409221462 TSSISGPLS(ph)PAYTGQVPYNYNQLEGR ddPTM_HeLa_Curcumin_4h_R1 1 TSSISGPLSPAYTGQVPYNYNQLEGR 26 0 Q01082-3 Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 T(0.008)S(0.008)S(0.007)IS(0.019)GPLS(0.939)PAY(0.013)T(0.005)GQVPYNYNQLEGR 112.9 2.86E-08 19630000 3687.6 2627.1 2950.9 3069.3 2528.4 5167.4 5881.8 8413.8 3111.3 2772.7 TRUE FALSE FALSE 3395.722569 2854.174818 3060.26295 3056.60005 2498.250481 4095.622991 6046.827478 10979.12889 2769.998174 2869.051119 1.183569908 0.994814906 1.066646366 1.065369672 0.870758442 1.427518306 2.107605347 3.82674565 0.965475364 1 11.48635796 -4.231893156 1.444699584 1.064999526 5.088934292 0.985921839 0.102258853 0.106599768 0.187151077 0.015982951 0.628447656 5.86E-05 4.231893156 4.023934766 up RDS(ph)SESQLASTESDKPTTGR ddPTM_HeLa_Curcumin_4h_R1 4 RDSSESQLASTESDKPTTGR 20 2 A0A087WVF1;Q96B23-2;Q96B23;K7EQH1 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 0 RDS(0.871)S(0.127)ES(0.002)QLASTESDKPTTGR;RDS(0.861)S(0.118)ES(0.021)QLASTESDKPTTGR;RDS(0.803)S(0.185)ES(0.012)QLASTESDKPTTGR;RDS(0.8)S(0.192)ES(0.005)QLAS(0.002)TESDKPTTGR ;;; 156.83 1.03E-05 239313600 7110.05 6547.95 6041.66 6930.18 6773.43 10505 12701.5 9582.6 7852.18 7161.92 TRUE FALSE FALSE 6547.28204 7113.925621 6265.569234 6901.504751 6692.661271 8326.144584 13057.86991 12504.29063 6990.815499 7410.796187 0.883478897 0.9599408 0.845465059 0.931277096 0.903096118 1.123515527 1.762006345 1.687307316 0.943328534 1 12.85541283 -4.850154629 3.585006172 0.935615098 1.735767114 0.975280328 0.050131093 0.026537849 0.655360235 0.008421797 0.029869406 1.41E-05 4.850154629 0.800152016 SVS(ph)VVTGSEQKR ddPTM_HeLa_Curcumin_4h_R1 1 SVSVVTGSEQKR 12 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 0 S(0.004)VS(0.996)VVTGSEQKR 82.578 0.010412 4652700 1858.7 1428.9 1945.1 2006.2 1805.6 2382.7 2322.9 4346.9 1643.6 1767.2 TRUE FALSE FALSE 1711.581934 1552.407749 2017.187117 1997.898876 1784.069399 1888.501161 2388.074322 5672.249799 1463.301192 1828.610068 0.936001591 0.848955048 1.103125894 1.09257786 0.975642336 1.032752249 1.305950549 3.101946061 0.80022593 1 10.83653175 -4.231823381 2.645066467 0.982965369 3.62378216 0.979428769 0.092024947 0.042733274 0.362809679 0.01088035 0.255896192 5.86E-05 4.231823381 2.640816792 up ANSTS(ph)DSVFTETPS(ph)PVLK ddPTM_HeLa_Curcumin_4h_R1 1 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 2 0 ANS(0.016)T(0.044)S(0.898)DS(0.041)VFT(0.001)ET(0.141)PS(0.859)PVLK 176.48 5.82E-19 0 2027.7 1542.2 2214.9 1646 1976.7 2922.1 2950.9 7215.3 2189.9 2189.3 TRUE FALSE FALSE 1867.205405 1675.500896 2296.986142 1639.189288 1953.129144 2316.023521 3033.694312 9415.211755 1949.673449 2265.378012 0.824235688 0.739612059 1.013952696 0.723583119 0.862164784 1.022356317 1.339155892 4.156132753 0.860639345 1 11.14553609 -4.231374728 2.756757967 0.89858649 4.914978265 0.988833491 0.10377545 0.039103572 0.373365215 0.016205293 0.366151857 5.87E-05 4.231374728 4.016391775 up RDSS(ph)DDWEIPDGQITVGQR ddPTM_HeLa_Curcumin_4h_R1 1 RDSSDDWEIPDGQITVGQR 19 1 H7C560;A0A2U3TZI2;A0A2R8Y8E0;P15056;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y679 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 0 RDS(0.391)S(0.609)DDWEIPDGQITVGQR 122.34 9.48E-05 18015000 1576.6 1036.4 1170.3 1243.5 1460.8 2077.6 1274.8 1132.5 1345.6 1426.9 TRUE FALSE FALSE 1451.810446 1125.981798 1213.672348 1238.354726 1443.380914 1646.682341 1310.567457 1477.794037 1197.991047 1476.484669 0.983288535 0.762609881 0.822001321 0.83871831 0.977579344 1.115272224 0.887626865 1.000886814 0.81138062 1 10.52795066 -3.256990991 14.29053589 0.958079466 0.934589466 0 0.112593043 0 0 0.014470711 0 0.000553362 3.256990991 -0.02349 TS(ph)DSDQQAYLVQR ddPTM_HeLa_Curcumin_4h_R1 1 TSDSDQQAYLVQR 13 0 Q96CV9-3;Q96CV9-2;Q96CV9 Q96CV9-3 OPTN Optineurin 1 0 T(0.015)S(0.492)DS(0.492)DQQAYLVQR 182.37 0.00021453 42568000 2009.4 1795.4 1861.7 1657.1 2167.5 3028.1 2596.3 4822 2391 2562.3 TRUE FALSE FALSE 1850.35387 1950.586376 1930.69624 1650.243359 2141.653978 2400.037926 2669.14519 6292.205602 2128.713282 2651.339734 0.697893916 0.735698391 0.728196472 0.622418673 0.80776294 0.905217048 1.006715645 2.373217404 0.802882126 1 11.37250583 -4.229411736 2.835361917 0.819526155 2.725266302 0.952651496 0.105212061 0.098646196 1.016911705 0.020079027 0.447334097 5.90E-05 4.229411736 1.905740147 up RDVYLS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 RDVYLSPR 8 1 P38159;P38159-2;H3BUY5;Q96E39;H0Y6E7;H3BT71 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 1 0 RDVYLS(1)PR;RDVYLS(1)PR;RDVYLS(1)PR ;; 97.779 0.0076644 112209000 12860 9558.2 10361.9 10071.9 12301.8 13306 9990.3 5684.9 11056.7 10132.7 TRUE FALSE FALSE 11842.11743 10384.36822 10745.92113 10030.22515 12155.10907 10546.18561 10270.60093 7418.19984 9843.807672 10484.81057 1.129454591 0.990420203 1.024903698 0.95664343 1.159306502 1.00585371 0.979569527 0.707518728 0.938863664 1 13.35601318 -4.147033075 1.82127223 1.051829651 0.520472751 0.638118149 0.069456417 0.505356943 1.323467167 0.00951381 0.502777905 7.13E-05 4.147033075 -0.5313569 RDYDDMS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 RDYDDMSPR 9 1 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 0 RDYDDMS(1)PR;RDYDDMS(1)PR ; 167.2 0.0011045 493730000 10724 8475.6 8828.5 9663.9 8687.2 11183.5 8809.7 5193.2 10163.3 9146 TRUE FALSE FALSE 9875.184084 9208.193097 9155.691976 9623.913342 8583.610814 8863.916036 9056.876472 6776.582773 9048.411417 9463.822819 1.043466712 0.972988746 0.967441186 1.016916052 0.906991918 0.936610523 0.956999792 0.716051315 0.956105328 1 13.20820735 -3.201555705 0.610361053 1.012987804 3.84E-26 0.71190094 0.045961431 3.574462971 0.351493376 0.00755259 3.435908386 0.000628701 3.201555705 -1.012987804 RDYDDMSPR ddPTM_HeLa_Curcumin_4h_R1 1 RDYDDMSPR 9 1 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 0 101.38 0.018053 6988200 1889 1448.5 1950.8 1563.3 1927.4 1639.8 1889.9 1523.3 1759.7 1528.1 FALSE FALSE TRUE 1739.483657 1573.701886 2023.098364 1556.831479 1904.417014 1299.686996 1942.925508 1987.747158 1566.665313 1581.201361 1.100102555 0.995257103 1.279469152 0.984587743 1.204411443 0.821961723 1.22876539 1.25711197 0.990806959 1 10.62680539 -2.344201371 0.014804482 4.39E-07 2.354346708 0.128721177 0.133972652 6900.680967 10.08996206 675.2962347 950.9510223 0.004526876 2.344201371 2.354346268 REDEGEPGDEGQLEDEGS(ph)QEKQGR ddPTM_HeLa_Curcumin_4h_R1 2 REDEGEPGDEGQLEDEGSQEKQGR 24 2 Q969E4 Q969E4 TCEAL3 Transcription elongation factor A protein-like 3 1 0 REDEGEPGDEGQLEDEGS(1)QEKQGR;REDEGEPGDEGQLEDEGS(1)QEKQGR ; 61.033 0.0015132 27496000 3574.4 2821.34 2952.1 3123.8 3757.2 3509.1 3432.5 4225.5 3441 3040.86 TRUE FALSE FALSE 3291.482468 3065.204058 3061.507423 3110.874543 3712.397844 2781.273104 3528.806712 5513.835498 3063.530909 3146.529659 1.046067517 0.974153874 0.972979045 0.988668432 1.179838821 0.883917651 1.121491641 1.752354529 0.97362213 1 11.61954583 -4.273872371 3.668985131 1.016338238 1.823810846 0.904881348 0.072407992 0.047971612 1.191796148 0.00888435 0.103405975 5.32E-05 4.273872371 0.807472608 REDFQDISVPVQEDELS(ph)KVEESSEISPEPK ddPTM_HeLa_Curcumin_4h_R1 1 REDFQDISVPVQEDELSKVEESSEISPEPK 30 2 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 0 REDFQDIS(0.003)VPVQEDELS(0.687)KVEES(0.105)S(0.143)EIS(0.062)PEPK 67.848 5.74E-05 58058000 4821.4 4052.5 4492.3 3805.7 4493.9 4756.3 2720.3 2802.8 4949.1 4378.5 TRUE FALSE FALSE 4439.781102 4402.780042 4658.78859 3789.953022 4440.313178 3769.789765 2796.624297 3657.360817 4406.196112 4530.652549 0.979942967 0.971776139 1.028282028 0.836513721 0.980060406 0.832063312 0.617267439 0.807248134 0.97253013 1 12.14550314 -5.081896306 3.07627835 0.979661579 0.7113485 0.707097913 0.065570603 0.087402291 1.591313188 0.008699397 0.026465449 8.28E-06 5.081896306 -0.268313079 REDFQDISVPVQEDELSKVEESSEIS(ph)PEPK ddPTM_HeLa_Curcumin_4h_R1 1 REDFQDISVPVQEDELSKVEESSEISPEPK 30 2 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 0 REDFQDISVPVQEDELS(0.274)KVEES(0.117)S(0.117)EIS(0.491)PEPK 70.112 4.55E-05 28372000 2474.9 1615.3 2320 2301.7 1930.8 2361.6 1478.9 1384.1 2230.3 2036.7 TRUE FALSE FALSE 2279.009053 1754.919334 2405.981241 2292.176175 1907.776471 1871.777539 1520.393954 1806.105718 1985.64167 2107.475173 1.081393073 0.832711747 1.141641558 1.087640891 0.905242679 0.888161134 0.721429117 0.85699976 0.942189827 1 11.04129992 -5.366073296 2.033501793 1.0331268 0.798442358 0.462237284 0.091531156 0.17839687 1.422724348 0.012510843 0.03572904 4.30E-06 5.366073296 -0.234684441 REDIFYTSK ddPTM_HeLa_Curcumin_4h_R1 4 REDIFYTSK 9 1 S4R3Z2;A0A0A0MSS8;P42330;S4R3D5;A6NHU4;P17516;P52895-2;H0Y804;Q04828;S4R3P0;B4DK69;P52895 S4R3Z2;H0Y804 AKR1C3;AKR1C1;AKR1C4;AKR1C2 Aldo-keto reductase family 1 member C3;Aldo-keto reductase family 1 member C4;Aldo-keto reductase family 1 member C2;Aldo-keto reductase family 1 member C1 0 0 ;;; ;;; 166.86 1.60E-08 152303500 22114.6 14707 18116.5 15474.1 18558.6 29082.2 21768.1 21943.2 20327.8 18657.1 FALSE FALSE TRUE 20364.20607 15978.20755 18787.91343 15410.07227 18337.30082 23050.2239 22378.8543 28633.58067 18097.8912 19305.43284 1.054843279 0.827653422 0.973193069 0.798224645 0.949851836 1.193976022 1.159199822 1.483187707 0.937450683 1 14.23671928 -4.266411394 1.17509091 0.988577151 1.693574659 0.73827722 0.09743783 0.698198421 0.78468823 0.015634218 0.600434322 5.41E-05 4.266411394 0.704997508 REDLVEEIK ddPTM_HeLa_Curcumin_4h_R1 1 REDLVEEIK 9 1 B4E1C5;B4DDD8;B3KWE1;P12081-3;P12081-2;P12081-4;P12081 B4E1C5 HARS "Histidine--tRNA ligase, cytoplasmic" 0 0 157.38 0.0015194 8100300 4389 3237.7 3944.3 3701.4 4260.1 4684.2 3497.8 3783 4332 3781.9 FALSE FALSE TRUE 4041.606019 3517.552361 4090.479228 3686.084588 4209.30109 3712.644118 3595.938854 4936.419285 3856.790438 3913.320744 1.032781692 0.898866357 1.045270627 0.941932652 1.075634063 0.948719607 0.918897042 1.261439991 0.98555439 1 11.93417765 -4.250279817 24.88492531 0.99980758 1.261440153 0.678834503 0.056393411 695.3856441 1550623.394 0.007315197 0.149785466 5.62E-05 4.250279817 0.261632573 REDLVVAPAGITLK ddPTM_HeLa_Curcumin_4h_R1 2 REDLVVAPAGITLK 14 1 P12268;H0Y4R1;E7ETK5 P12268 IMPDH2 Inosine-5-monophosphate dehydrogenase 2 0 0 ; ; 141 7.41E-16 0 4934.8 4707 4294.3 4248.3 4102.9 6272.7 5066.5 4879.5 5199 4423.8 FALSE FALSE TRUE 4544.205373 5113.852106 4453.450536 4230.72166 4053.975597 4971.671312 5208.652354 6367.237088 4628.682707 4577.526721 0.992720666 1.117164884 0.972894492 0.924237458 0.885625764 1.086104269 1.137874811 1.39097759 1.011175464 1 12.16035259 -4.302668103 1.548175229 0.993049565 1.517465771 0.799191952 0.061087894 0.324116895 0.757875978 0.008909481 0.250949719 4.98E-05 4.302668103 0.524416206 REDS(ph)FESLDSLGSR ddPTM_HeLa_Curcumin_4h_R1 3 REDSFESLDSLGSR 14 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;E9PMP7 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 REDS(1)FESLDSLGSR;REDS(1)FESLDSLGSR;REDS(1)FESLDSLGSR ;; 179.9 6.26E-05 85345000 4180.24 3106.11 3724.92 4463.81 3625.27 4486.64 4068.51 4504 4109.72 3730.64 TRUE FALSE FALSE 3849.369593 3374.588308 3862.968812 4445.339937 3582.041023 3556.060289 4182.661441 5877.248866 3658.893998 3860.279462 0.997173814 0.874182385 1.000696672 1.151559098 0.927922721 0.921192448 1.083512601 1.522493105 0.947831377 1 11.91448958 -4.277586009 3.286321757 0.991664176 1.586147999 0.837952542 0.071413276 0.084086311 1.477705699 0.009433122 0.123602471 5.28E-05 4.277586009 0.594483823 REDS(ph)PGPEVQPMDK ddPTM_HeLa_Curcumin_4h_R1 3 REDSPGPEVQPMDK 14 1 O75382-3;O75382-2;O75382;E9PMW5;E9PMK8 O75382-3 TRIM3 Tripartite motif-containing protein 3 1 0 REDS(1)PGPEVQPMDK;REDS(1)PGPEVQPMDK;REDS(1)PGPEVQPMDK ;; 118.23 0.0009079 251314000 12583.1 10322.3 11623.4 11344.7 11313.5 13897.9 10374.4 9610 13267.4 11245.5 TRUE FALSE FALSE 11587.13436 11214.51362 12054.17343 11297.75864 11178.5939 11015.31888 10665.47774 12540.04476 11811.99941 11636.28029 0.995776491 0.963754167 1.035912949 0.970908087 0.960667294 0.946635747 0.916571059 1.077667816 1.015100971 1 13.50634233 -6.043659049 24.87998432 0.997685946 0.968712961 0.083551336 0.042505326 730.9060589 416520.3275 0.005778203 0.009582495 9.04E-07 6.043659049 -0.028972985 REEAAVDAQQQK ddPTM_HeLa_Curcumin_4h_R1 2 REEAAVDAQQQK 12 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 182.23 4.75E-10 3805900 3134.7 2562.9 2959 3214.4 3807.8 3622.9 3044.4 3027.1 3337.1 3244.1 FALSE FALSE TRUE 2886.585187 2784.425656 3068.663143 3201.099665 3762.394472 2871.469702 3129.81767 3950.048855 2971.028479 3356.832234 0.85991345 0.829480136 0.914154456 0.953607283 1.120816952 0.855410548 0.932372383 1.176719175 0.885069099 1 11.71288472 -5.99082333 24.97619497 0.921882337 1.007385273 0.251269567 0.094952399 318.2570844 866194.5217 0.014869811 0.02692794 1.02E-06 5.99082333 0.085502936 REEAAVDAQQQKR ddPTM_HeLa_Curcumin_4h_R1 1 REEAAVDAQQQKR 13 2 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 65.234 0.018744 703860 487.12 359.24 258.98 89.463 223.81 153.92 345 165.58 203.28 369.25 FALSE FALSE TRUE 448.563938 390.2911049 268.5780266 89.09282581 221.1412119 121.995257 354.6797715 216.0645798 180.9806926 382.08141 1.174000949 1.021486769 0.702934033 0.233177599 0.578780349 0.319291266 0.928283246 0.565493568 0.4736705 1 8.577736256 -6.69243883 3.458852534 1.082248447 0.533943582 0.252471267 0.26182106 0.103183232 2.485851135 0.028817279 0.040965568 2.03E-07 6.69243883 -0.548304865 REEDEENDNDNES(ph)DHDEADS ddPTM_HeLa_Curcumin_4h_R1 1 REEDEENDNDNESDHDEADS 20 1 H0YBP8;Q9NRG0 H0YBP8 CHRAC1 Chromatin accessibility complex protein 1 1 0 REEDEENDNDNES(0.715)DHDEADS(0.285) 84.689 0.00094193 5348600 683.03 748.35 667.7 845.31 738.05 789.66 883.54 748.23 832.43 650.63 TRUE FALSE FALSE 628.9674548 813.0340394 692.4455494 841.8123312 729.2492358 625.8756147 908.3297545 976.3618826 741.1145116 673.2393441 0.93424049 1.207644869 1.028528049 1.250390873 1.08319462 0.929648007 1.349192917 1.450244837 1.100818777 1 9.39497568 -1 0.402816191 0.985692647 8.726855891 0.441568392 0.124979914 34.06857248 0.40063191 0.029597723 212.0598951 0.1 1 7.741163243 REEDEPEER ddPTM_HeLa_Curcumin_4h_R1 1 REEDEPEER 9 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 0 0 98.943 0.020148 1114100 298.1 412.78 300.68 229.53 288.78 385.71 298.6 175.84 296.6 316.7 FALSE FALSE TRUE 274.5050704 448.4588639 311.8234653 228.5802657 285.3364871 305.7093982 306.9779124 229.4528065 264.0637221 327.7053014 0.837658315 1.368482176 0.951536225 0.697517754 0.870710623 0.932879013 0.936749912 0.700180331 0.805796308 1 8.356255202 -6.484283259 24.31663482 0.964364641 0.840175287 0.19353991 0.162659791 678.3226189 427369.2286 0.025247208 0.038559681 3.28E-07 6.484283259 -0.124189354 REEDEPEERSGDETPGS(ph)EVPGDK ddPTM_HeLa_Curcumin_4h_R1 1 REEDEPEERSGDETPGSEVPGDK 23 2 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 0 REEDEPEERS(0.007)GDET(0.387)PGS(0.607)EVPGDK 80.016 0.0003986 119750000 1951.7 2172.5 2047.3 2180.5 2417.7 2661.9 2217.4 1792.1 2059.5 1978.7 TRUE FALSE FALSE 1797.220886 2360.28122 2123.174739 2171.477669 2388.870507 2109.791934 2279.614276 2338.50304 1833.578003 2047.459678 0.877780845 1.152785203 1.036980001 1.06057164 1.166748499 1.030443704 1.113386652 1.14214852 0.895538028 1 10.99961932 -7.259517513 24.99998485 0.942285398 1.096820122 0.685750497 0.054156203 88.20384172 1147373.761 0.010193308 0.012148155 5.50E-08 7.259517513 0.154534724 REEEFDLFMR ddPTM_HeLa_Curcumin_4h_R1 1 REEEFDLFMR 10 1 A0A0U1RQZ9;F6VDE0;P51531-2;P51531;A0A0U1RRG6 A0A0U1RQZ9 SMARCA2 Probable global transcription activator SNF2L2 0 0 93.442 0.016646 5483100 2000.2 1514 1850.7 1854.6 1789.9 2065.5 1860.3 1309 2183.7 1899.7 FALSE FALSE TRUE 1841.882059 1644.863414 1919.28857 1846.926157 1768.556612 1637.092017 1912.495011 1708.108074 1944.153573 1965.714434 0.937003884 0.836776383 0.976382193 0.939569922 0.899701697 0.832822911 0.972926168 0.868950263 0.98903154 1 10.94083804 -8.536440972 0.494373135 1.0074246 0.902818018 0.343454669 0.047990616 0.858395809 0.420481887 0.040798436 0.014535652 2.91E-09 8.536440972 -0.104606583 REEEMMIR ddPTM_HeLa_Curcumin_4h_R1 1 REEEMMIR 8 1 P23246;P23246-2;H0Y9K7 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 0 119.21 0.012486 2547900 977.93 1049 728.74 872.37 756.94 968.78 814.3 848.92 1120.9 857.33 FALSE FALSE TRUE 900.5258086 1139.670886 755.7477455 868.7603641 747.9139849 767.8441076 837.1470664 1107.7518 997.9400744 887.1221537 1.015109142 1.284683153 0.851909449 0.979301848 0.843078917 0.865544958 0.943666059 1.248702668 1.124918446 1 9.792988962 REEGPPPPSPDGAS(ph)SDAEPEPPSGR ddPTM_HeLa_Curcumin_4h_R1 1 REEGPPPPSPDGASSDAEPEPPSGR 25 1 C9JWF0;C9IYK2;C9JJ64;C9JR83;Q9NTJ3-2;Q9NTJ3;F8WCB7;E9PD53 C9JWF0 SMC4 Structural maintenance of chromosomes protein 4;Structural maintenance of chromosomes protein 1 0 REEGPPPPSPDGAS(0.75)S(0.249)DAEPEPPS(0.001)GR 143.03 7.39E-09 0 614.28 697.6 577.37 517.69 616.86 792.43 590.02 379.25 577.73 625.99 TRUE FALSE FALSE 565.6590898 757.8974356 598.7678401 515.5479359 609.5043474 628.0710855 606.5743732 494.8815791 514.3544644 647.7431059 0.873276897 1.170058668 0.924390912 0.7959142 0.940966167 0.969629904 0.936442808 0.764009026 0.794071692 1 9.339277945 -6.523230209 24.99999827 0.960085936 0.889411506 0.102045025 0.107958587 22.76536969 1619299.207 0.015728246 0.022368133 3.00E-07 6.523230209 -0.070674431 REELITNWEQIR ddPTM_HeLa_Curcumin_4h_R1 2 REELITNWEQIR 12 1 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 ; ; 179.46 0.00015762 12492400 3890 3488.7 4080.9 3568.9 4555.4 3704 3390.8 3444.6 3290.5 2921.9 FALSE FALSE TRUE 3582.102395 3790.247683 4232.141744 3554.132837 4501.07983 2935.748647 3485.936722 4494.842683 2929.540382 3023.435808 1.184778716 1.253622674 1.399778931 1.175527798 1.48873008 0.970997512 1.152971964 1.486667146 0.968944131 1 11.56197323 -8.364184914 0.703491466 1.012302407 1.26754853 0.352344573 0.151956464 0.56916631 0.600248394 0.067823401 0.035182491 4.32E-09 8.364184914 0.255246123 REEQTDT(ph)SDGESVTHHIR ddPTM_HeLa_Curcumin_4h_R1 1 REEQTDTSDGESVTHHIR 18 1 A2AB27;P36915 A2AB27 GNL1 Guanine nucleotide-binding protein-like 1 1 0 REEQT(0.014)DT(0.492)S(0.492)DGES(0.001)VTHHIR 93.006 0.0016998 13627000 1996.1 1908.5 1864.8 1666 2214.4 2970.6 1648.4 1610.2 2454.7 1849.7 TRUE FALSE FALSE 1838.106579 2073.462236 1933.911128 1659.106533 2187.994726 2354.464074 1694.649668 2101.142568 2185.425551 1913.976937 0.960359837 1.083326656 1.010415063 0.866837265 1.143166714 1.230142343 0.885407569 1.097788864 1.141824391 1 10.90235773 -5.737760693 24.99994318 0.984624044 1.08464758 0.086099533 0.106902187 284.8601853 300753.6408 0.013307599 0.02660355 1.83E-06 5.737760693 0.100023536 REEQTDTS(ph)DGESVTHHIR ddPTM_HeLa_Curcumin_4h_R1 1 REEQTDTSDGESVTHHIR 18 1 A2AB27;P36915 A2AB27 GNL1 Guanine nucleotide-binding protein-like 1 1 0 REEQT(0.008)DT(0.224)S(0.768)DGESVTHHIR 103.92 0.0010247 9790500 1399 1168.1 913.06 1140.7 1274.4 2347.7 1147.1 1190.6 1437.6 1568.9 TRUE FALSE FALSE 1288.267674 1269.065359 946.8988068 1135.980086 1259.203612 1860.760556 1179.284539 1553.608459 1279.898877 1623.419158 0.793552095 0.781723779 0.583274382 0.699745398 0.775649102 1.14619847 0.726420243 0.956997736 0.788397051 1 10.66481983 -3.924144374 18.28584729 0.856338356 3.411840284 0.001794596 0.155324752 466.0089842 121832.9031 0.022916498 4071.535056 0.000119085 3.924144374 2.555501928 REESPMDVDQPS(ph)PSAQDTQSIASDGTPQGEK ddPTM_HeLa_Curcumin_4h_R1 3 REESPMDVDQPSPSAQDTQSIASDGTPQGEK 31 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 REESPMDVDQPS(0.499)PS(0.499)AQDT(0.003)QSIASDGTPQGEK;REESPMDVDQPS(0.726)PS(0.264)AQDT(0.008)QS(0.001)IASDGTPQGEK;REESPMDVDQPS(0.794)PS(0.205)AQDT(0.001)QSIASDGTPQGEK ;; 104.32 7.61E-11 53211800 6207.2 6115.4 7162.4 5489.5 6711.9 7479.5 5796.8 5844 5994.9 6183.7 TRUE FALSE FALSE 5715.89357 6643.987926 7427.844845 5466.785904 6631.864976 5928.167389 5959.442607 7625.808698 5337.274469 6398.583115 0.893306138 1.038352993 1.160857757 0.854374446 1.036458362 0.926481267 0.931369102 1.191796459 0.834133803 1 12.64353676 -7.242631634 24.47986976 0.949616784 1.012638926 0.153061567 0.106496984 1285.610877 1673331.904 0.016534982 0.020231897 5.72E-08 7.242631634 0.063022142 REESPMDVDQPSPS(ph)AQDTQSIASDGTPQGEK ddPTM_HeLa_Curcumin_4h_R1 1 REESPMDVDQPSPSAQDTQSIASDGTPQGEK 31 1 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7;H0Y659 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 REESPMDVDQPS(0.196)PS(0.786)AQDT(0.017)QSIASDGTPQGEK 108.52 4.65E-11 27904000 3121.5 2609.1 2776.9 3142.9 3340.3 3552.9 2249.4 2801.3 2640.9 2508.8 TRUE FALSE FALSE 2874.429981 2834.618978 2879.814357 3129.895513 3300.469104 2815.988491 2312.51211 3655.403474 2351.199877 2595.980613 1.107261729 1.091926097 1.109335849 1.205669833 1.271376638 1.08474943 0.890804846 1.408101222 0.905707795 1 11.34206389 -8.61622956 0.395316389 0.977549116 1.156536063 0.257948115 0.129743963 2.210574422 0.658952585 0.166273042 0.051116949 2.42E-09 8.61622956 0.178986947 REFITGDVEPTDAES(ph)EWHSENEEEEKLAGDMK ddPTM_HeLa_Curcumin_4h_R1 1 REFITGDVEPTDAESEWHSENEEEEKLAGDMK 32 2 C9J6D1;Q99733;Q99733-2;E9PNJ7;A8MXH2;E9PKT8;C9JZI7 C9J6D1 NAP1L4 Nucleosome assembly protein 1-like 4 1 0 REFITGDVEPT(0.002)DAES(0.499)EWHS(0.499)ENEEEEKLAGDMK 44.743 0.0086845 37496000 1882.4 1426.7 1662.9 1140.9 2050.6 2597.9 1586.4 1930.7 2040.6 1708.1 TRUE FALSE FALSE 1733.406054 1550.017591 1724.528537 1136.179258 2026.147934 2059.066256 1630.910114 2519.361542 1816.751285 1767.456348 0.98073486 0.876976448 0.975712095 0.642832995 1.146363777 1.164988464 0.922744212 1.425416557 1.027890328 1 10.78745887 -1.937363242 1.287403869 0.971890119 200 0.468879197 0.141570115 458.7065888 2.139687203 0.019827489 268105.2443 0.011551457 1.937363242 199.0281099 REFITGDVEPTDAESEWHS(ph)ENEEEEK ddPTM_HeLa_Curcumin_4h_R1 2 REFITGDVEPTDAESEWHSENEEEEK 26 1 C9J6D1;Q99733;Q99733-2;E9PNJ7;A8MXH2;E9PKT8;C9JZI7;E9PS34 C9J6D1 NAP1L4 Nucleosome assembly protein 1-like 4 1 0 REFITGDVEPT(0.015)DAES(0.323)EWHS(0.662)ENEEEEK;REFITGDVEPT(0.053)DAES(0.194)EWHS(0.753)ENEEEEK ; 56.588 0.0057147 25719000 2433.03 2035.54 2129.25 2197.42 3350.9 3327.7 2700.4 2491.84 2436.27 2407.7 TRUE FALSE FALSE 2240.453108 2211.483007 2208.161878 2188.327658 3310.942706 2637.497509 2776.165956 3251.590545 2169.017276 2491.367396 0.899286517 0.887658324 0.886325269 0.878364091 1.328966058 1.058654582 1.114314156 1.305142931 0.870613174 1 11.28272207 -5.773963106 24.99999974 0.935795488 1.185300149 0.736073692 0.085934342 99.98773986 199596.6586 0.012765536 0.023254629 1.68E-06 5.773963106 0.249504662 REGKWHK ddPTM_HeLa_Curcumin_4h_R1 1 REGKWHK 7 2 H3BN32;Q9ULG6-3;Q9ULG6-5 H3BN32 CCPG1 0 0 104.11 0.012242 21689000 2356.7 1601.1 1723.7 3156.8 1231.4 5413.6 2766.7 1653.1 4325.7 2696.4 FALSE FALSE TRUE 2170.164708 1739.49195 1787.581838 3143.737998 1216.716359 4290.758336 2844.326156 2157.12258 3851.181532 2790.099699 0.777809018 0.623451538 0.640687442 1.126747549 0.43608347 1.537851259 1.019435311 0.773134587 1.380302479 1 11.44610096 -5.265393581 24.99909776 0.843699219 1.101069861 0.123987586 0.30946537 449.9849633 2844885.32 0.036136366 0.083716056 5.43E-06 5.265393581 0.257370642 ANVVTT(ph)PSTNR ddPTM_HeLa_Curcumin_4h_R1 1 ANVVTTPSTNR 11 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;E9PDP5 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 0 ANVVT(0.067)T(0.773)PS(0.12)T(0.04)NR 125.36 0.010151 14732000 3911.6 3411.6 3808.6 3704.4 3826.9 3429.6 2519.6 766.12 3346.5 3044.1 TRUE FALSE FALSE 3601.992732 3706.483502 3949.750066 3689.072174 3781.266717 2718.2623 2590.293195 999.7064612 2979.397323 3149.882248 1.143532503 1.176705416 1.253935784 1.171177804 1.200447007 0.862972672 0.82234604 0.317378995 0.945875778 1 11.62108218 -4.267874664 1.270756722 1.104897835 9.89E-14 0.846401952 0.103980617 0.412506904 0.56083808 0.016072076 0.591205842 5.40E-05 4.267874664 -1.104897835 down T(ph)GSES(ph)SQTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 2 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 0 T(0.769)GS(0.23)ES(0.566)S(0.401)QT(0.032)GT(0.001)STTSSR;T(0.994)GS(0.006)ES(0.922)S(0.077)QT(0.001)GTSTTSSR ; 159.14 0.0012375 243736200 10055.3 10252.5 10871.3 10622.7 11639.1 11645.7 8181 3807.04 9540.2 9650.5 TRUE FALSE FALSE 9259.412395 11138.68042 11274.19994 10578.74608 11500.31133 9230.250546 8410.536842 4967.788971 8493.663928 9985.854157 0.927252917 1.115445934 1.129017084 1.059373181 1.151660254 0.924332601 0.842245111 0.497482628 0.850569595 1 13.28567012 -4.267747884 1.722227062 1.006406751 0.327252141 0.750335586 0.092403301 0.358847323 1.037719782 0.01339287 0.39800345 5.40E-05 4.267747884 -0.67915461 down AGTDS(ph)PVSCASVTEER ddPTM_HeLa_Curcumin_4h_R1 4 AGTDSPVSCASVTEER 16 0 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 0 AGT(0.046)DS(0.948)PVS(0.006)CASVTEER;AGT(0.002)DS(0.975)PVS(0.023)CASVTEER;AGTDS(1)PVSCASVTEER;AGT(0.001)DS(0.999)PVSCASVTEER ;;; 335.24 1.21E-132 189253000 10454.7 8775.9 8938.2 9588.7 9507.5 11332.6 7151.14 2561.66 10619.6 8105.7 TRUE FALSE FALSE 9627.199463 9534.449691 9269.457555 9549.0245 9394.129272 8982.091015 7351.781742 3342.698342 9454.656449 8387.372472 1.147820667 1.136762404 1.105168226 1.138500112 1.120032442 1.070906419 0.876529779 0.398539394 1.127248907 1 13.03400321 -4.267676671 1.948263655 1.088042965 0.192972123 0.959319501 0.044278563 0.150385141 0.59819682 0.009064608 0.239986237 5.40E-05 4.267676671 -0.895070842 down REILRGT(ph)Y(ph)AELMK ddPTM_HeLa_Curcumin_4h_R1 1 REILRGTYAELMK 13 2 C9J1S8 C9J1S8 TRIM49D1 Tripartite motif-containing protein 49D1 2 0 REILRGT(1)Y(1)AELMK 68.809 0.013523 7347600 3119.2 2177.6 2492.9 2776.9 2766.4 4315.9 3221 2569.8 2999.9 2358.5 TRUE FALSE FALSE 2872.312029 2365.822041 2585.289067 2765.409924 2733.412487 3420.73369 3311.372591 3353.32019 2670.818475 2440.457699 1.176956285 0.969417352 1.059345986 1.133152164 1.12004092 1.401677108 1.356865391 1.374053806 1.094392448 1 11.25293603 -5.326764552 4.042230761 1.078708751 1.376927103 0.849956996 0.057611292 0.080191216 2.601281999 0.010886175 0.026014626 4.71E-06 5.326764552 0.298218351 REPAEQPGDGER ddPTM_HeLa_Curcumin_4h_R1 2 REPAEQPGDGER 12 1 Q15424-2;Q15424;Q15424-4;Q15424-3;Q14151 Q15424-2;Q14151 SAFB;SAFB2 Scaffold attachment factor B1;Scaffold attachment factor B2 0 0 ; ; 92.925 0.0048722 723310 179.44 241.7 380.91 153.55 364.3 290.571 409.88 214.35 354.41 280.18 FALSE FALSE TRUE 165.2371347 262.591471 395.0268597 152.9146508 359.9559604 230.3032992 421.3801297 279.7043283 315.5321097 289.9162341 0.569947851 0.905749455 1.362555156 0.52744425 1.241586079 0.794378762 1.453454757 0.964776357 1.088356127 1 8.179492311 -5.58377953 0.713501133 0.815842551 1.180557095 0.003253903 0.293299459 1.280696327 1.07195738 0.054178887 0.265984568 2.61E-06 5.58377953 0.364714544 REPEDEGEDDD ddPTM_HeLa_Curcumin_4h_R1 1 REPEDEGEDDD 11 1 P39687 P39687 ANP32A Acidic leucine-rich nuclear phosphoprotein 32 family member A 0 0 143.7 0.0067843 13112000 4881 4082.6 4505 3883 4516.1 5654.9 4483.5 4219.9 4712.3 4499.1 FALSE FALSE TRUE 4494.6637 4435.481752 4671.959263 3866.933175 4462.248457 4482.009996 4609.294943 5506.528084 4195.37248 4655.44339 0.965464151 0.952751732 1.003547648 0.830626183 0.958501282 0.962746106 0.990087207 1.182814959 0.901175705 1 12.18470286 -4.259695987 3.748928243 0.968836821 1.205588453 0.635844484 0.05126021 0.129403824 3.423868396 0.006671186 0.084750313 5.50E-05 4.259695987 0.236751632 REPGENGTSLT(ph)DEELVTMSVR ddPTM_HeLa_Curcumin_4h_R1 1 REPGENGTSLTDEELVTMSVR 21 1 I3L2F8;O15525 I3L2F8 MAFG Transcription factor MafG 1 0 REPGENGTS(0.001)LT(0.968)DEELVT(0.03)MS(0.001)VR 57.616 0.011101 5572900 1471.8 1240.2 1295.8 1325.7 1294.5 1760.1 1230.4 3684.9 1353.5 1418.4 TRUE FALSE FALSE 1355.305477 1347.397362 1343.823488 1320.214605 1279.063933 1395.03542 1264.921713 4808.409047 1205.024436 1467.689294 0.923428059 0.91803992 0.915604885 0.899519135 0.871481408 0.950497782 0.861845704 3.276176412 0.821035107 1 10.51933087 -4.260269482 24.99999515 0.940463559 3.276177159 0.993706325 0.056511291 4.795592817 102466.115 0.007148982 0.059150689 5.49E-05 4.260269482 2.3357136 REPLPSR ddPTM_HeLa_Curcumin_4h_R1 2 REPLPSR 7 1 P38159;P38159-2;H3BUY5;Q96E39;H0Y6E7;H3BT71;Q8IZ40 P38159 RBMX;RBMXL1;RCOR2 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1;REST corepressor 2" 0 0 ; ; 128.61 0.011337 4263900 2648.02 2216.25 2608.54 2875.11 3085.15 2721.73 2665.79 2313.18 2409.85 2123.54 FALSE FALSE TRUE 2438.426423 2407.812775 2705.214787 2863.213557 3048.361601 2157.212518 2740.584893 3018.457933 2145.495484 2197.332857 1.109721003 1.095788818 1.231135637 1.303040433 1.387300787 0.981741347 1.247232473 1.373691712 0.976408958 1 11.10153771 -7.312650203 0.715434269 1.024855368 1.254739687 0.465389619 0.110178479 0.436881649 0.47212932 0.030217497 0.034755291 4.87E-08 7.312650203 0.229884319 REQGGSGLGSGS(ph)SGGGGSTSGLGSGYIGR ddPTM_HeLa_Curcumin_4h_R1 1 REQGGSGLGSGSSGGGGSTSGLGSGYIGR 29 1 Q2M2I8-2;Q2M2I8;E9PG46 Q2M2I8-2 AAK1 AP2-associated protein kinase 1 1 0 REQGGSGLGS(0.009)GS(0.905)S(0.086)GGGGSTSGLGSGYIGR 91.249 7.24E-08 8013700 991.29 1185.1 991.52 1158.8 1043.9 1141.3 813.3 635.84 1340.6 1264.1 TRUE FALSE FALSE 912.8283505 1287.534763 1028.266603 1154.005193 1031.452174 904.5815149 836.1190091 829.704689 1193.539534 1308.027381 0.697866393 0.984333189 0.786120091 0.882248498 0.788555492 0.691561605 0.639221335 0.634317524 0.912472897 1 10.35317703 -13.52287875 0.148792257 1.83709123 0.665050595 0.463054867 0.095310236 50.40175894 0.512517776 12.65942569 0.260490296 3.00E-14 13.52287875 -1.172040635 REQGGSGLGSGSS(ph)GGGGSTSGLGSGYIGR ddPTM_HeLa_Curcumin_4h_R1 1 REQGGSGLGSGSSGGGGSTSGLGSGYIGR 29 1 Q2M2I8-2;Q2M2I8;E9PG46 Q2M2I8-2 AAK1 AP2-associated protein kinase 1 1 0 REQGGSGLGS(0.009)GS(0.383)S(0.544)GGGGS(0.04)T(0.017)S(0.007)GLGSGYIGR 74.381 5.08E-05 10289000 901.99 894.78 763.56 957.98 972.06 1049.9 607.45 682.8 1030.1 771.6 TRUE FALSE FALSE 830.5965397 972.1207961 791.8582053 954.0161326 960.4688194 832.1389052 624.4934121 890.9825768 917.1006072 798.4130426 1.040309333 1.217566277 0.991790168 1.194890466 1.202972357 1.042241122 0.78216835 1.115941911 1.148654341 1 9.640991478 -3.922743195 22.09997236 1.041419758 4.917305882 0 0.127894976 4518.542574 1220776.083 0.016666677 48548.20395 0.000119469 3.922743195 3.875886124 RES(ph)DESGESAPDEGGEGAR ddPTM_HeLa_Curcumin_4h_R1 2 RESDESGESAPDEGGEGAR 19 1 Q7Z3C6;H7C152;Q7Z3C6-2 Q7Z3C6 ATG9A Autophagy-related protein 9A 1 0 RES(0.994)DES(0.004)GES(0.002)APDEGGEGAR;RES(0.997)DES(0.003)GESAPDEGGEGAR ; 140.67 9.55E-05 5647400 1071.45 992.87 1178.13 951.98 1017.76 945.54 651.24 924.97 1222.6 1090.88 TRUE FALSE FALSE 986.6436019 1078.689259 1221.792534 948.040959 1005.623877 749.4243456 669.5120417 1206.989095 1088.483839 1128.787999 0.874073434 0.955617228 1.082393271 0.839875123 0.890888172 0.663919484 0.593124699 1.069278816 0.964294305 1 10.14055884 -5.67692507 2.236158972 0.948515213 0.762675769 0.261677431 0.13115528 0.293598769 2.979182272 0.019078745 0.042971513 2.10E-06 5.67692507 -0.185839444 IPSFFPSPEEPPSPS(ph)APSIAK ddPTM_HeLa_Curcumin_4h_R1 1 IPSFFPSPEEPPSPSAPSIAK 21 0 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 IPSFFPSPEEPPS(0.403)PS(0.469)APS(0.129)IAK 71.073 0.0014026 5564300 1191.3 1274 1302.9 1293.2 1146.6 1927.3 1755.6 3934.9 1563.9 1485.2 TRUE FALSE FALSE 1097.007348 1384.118883 1351.18662 1287.849081 1132.927544 1527.556255 1804.857411 5134.632896 1392.344083 1536.810589 0.713820789 0.90064377 0.879214803 0.838001176 0.737193999 0.99397822 1.174417605 3.34109677 0.905995893 1 10.58572365 -4.229172473 2.793605611 0.862701027 3.915798969 0.985231354 0.090137514 0.05229693 0.516042401 0.016607796 0.376354951 5.90E-05 4.229172473 3.053097942 up RES(ph)EDDPES(ph)EPDDHEK ddPTM_HeLa_Curcumin_4h_R1 2 RESEDDPESEPDDHEK 16 1 P16383-3;P16383-4;P16383 P16383-3 GCFC2 GC-rich sequence DNA-binding factor 2 2 0 RES(1)EDDPES(1)EPDDHEK;RES(1)EDDPES(1)EPDDHEK ; 83.359 0.0042241 54869000 8430.2 7253.2 8418.7 7296.5 9034.4 8472.1 7385.8 5233.8 7680.1 7414.1 TRUE FALSE FALSE 7762.940774 7880.134288 8730.704428 7266.309016 8926.670681 6714.89096 7593.02567 6829.561527 6837.612245 7671.739423 1.011887963 1.027163966 1.138034538 0.94715274 1.163578452 0.875276204 0.989739778 0.890223344 0.891272744 1 12.905338 -5.20033596 24.99999971 1.022195323 0.925545786 0.26964511 0.080435847 217.2140702 88870.84726 0.008894707 0.022677141 6.30E-06 5.20033596 -0.096649537 RES(ph)GAAEQVDNK ddPTM_HeLa_Curcumin_4h_R1 1 RESGAAEQVDNK 12 1 Q9P2R3;Q9P2R3-2;Q9P2R3-4 Q9P2R3 ANKFY1 Rabankyrin-5 1 0 RES(1)GAAEQVDNK 124.81 0.0048411 2820600 1749.4 1750.8 1996.3 1700.1 1818.7 1792.2 1811.5 1860.6 1920 1619.9 TRUE FALSE FALSE 1610.933144 1902.131351 2070.284634 1693.065437 1797.01319 1420.477518 1862.325815 2427.888375 1709.380804 1676.191404 0.961067537 1.134793643 1.235112308 1.010066889 1.072081139 0.847443504 1.111046035 1.448455331 1.019800483 1 10.71097118 -4.308965234 3.550379661 1.010854647 1.479605006 0.593749652 0.100137537 0.125173616 2.727237152 0.014469834 0.143298819 4.91E-05 4.308965234 0.468750358 RVPLS(ph)PLSLLAGPADAR ddPTM_HeLa_Curcumin_4h_R1 2 RVPLSPLSLLAGPADAR 17 1 Q5T4K5;H0YDQ8;Q53ET0 Q5T4K5 CRTC2 CREB-regulated transcription coactivator 2 1 0 RVPLS(0.89)PLS(0.11)LLAGPADAR;RVPLS(0.995)PLS(0.005)LLAGPADAR ; 85.013 0.0032063 22306600 2594.9 2114.54 2379.4 2209.57 2169.32 3189.7 2504.67 3975.5 2770.4 2066.53 TRUE FALSE FALSE 2389.510927 2297.311415 2467.582657 2200.427385 2143.452276 2528.120265 2574.944299 5187.611649 2466.494051 2138.341764 1.117459785 1.07434249 1.153970193 1.029034471 1.002389942 1.182280732 1.204178089 2.425997442 1.153461104 1 11.06227674 -4.22804316 2.956333126 1.067046907 2.717997609 0.973828262 0.06525032 0.050532073 0.586803318 0.009457852 0.204266863 5.92E-05 4.22804316 1.650950703 up RES(ph)PSPAPK ddPTM_HeLa_Curcumin_4h_R1 1 RESPSPAPK 9 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 RES(0.998)PS(0.002)PAPK 77.124 0.01697 10956000 3737.5 6688.7 3535.3 3221.8 2833.1 3247.5 3038.1 3317.8 2217.3 3429.9 TRUE FALSE FALSE 3441.672931 7266.841424 3666.321328 3208.469045 2799.317133 2573.931893 3123.340909 4329.381947 1974.067737 3549.08877 0.969734249 2.047523152 1.033031735 0.904026147 0.788742495 0.725237395 0.880040233 1.219857329 0.556218192 1 11.79323294 -6.291673528 5.675599383 1.085643107 0.885511341 0.075002105 0.370844756 0.432202124 43.12856691 0.053718494 0.083941328 5.11E-07 6.291673528 -0.200131766 RES(ph)PSPAPKPR ddPTM_HeLa_Curcumin_4h_R1 2 RESPSPAPKPR 11 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 RES(0.999)PS(0.001)PAPKPR;RES(1)PSPAPKPR ; 104.81 0.0062312 157321600 4401.3 3902.1 4103 4440.8 4330.7 4959.2 4147.5 4328.2 4983.4 4434.7 TRUE FALSE FALSE 4052.932461 4239.380137 4255.060789 4422.425146 4279.059231 3930.606018 4263.867688 5647.848255 4436.733488 4588.805495 0.883221672 0.923852654 0.927269808 0.963742122 0.932499587 0.856564093 0.929189021 1.230788331 0.966860219 1 12.16390294 -4.260744724 24.65299704 0.935021167 1.230788439 0.841865985 0.038890565 17.32711419 614773.6618 0.006901678 0.055326495 5.49E-05 4.260744724 0.295767272 RESESES(ph)DET(ph)PPAAPQLIK ddPTM_HeLa_Curcumin_4h_R1 3 RESESESDETPPAAPQLIK 19 1 O60832 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 2 0 RES(0.048)ES(0.037)ES(0.926)DET(0.988)PPAAPQLIK;RES(0.153)ES(0.223)ES(0.752)DET(0.873)PPAAPQLIK;RES(0.07)ES(0.215)ES(0.716)DET(0.999)PPAAPQLIK ;; 92.551 0.0012514 16947900 4742.4 4719.8 4650.9 4990.6 6012.8 5383.4 4243.9 3381.6 4833.1 4294.9 TRUE FALSE FALSE 4367.034036 5127.758481 4823.266445 4969.95022 5941.101287 4266.822157 4362.972412 4412.634273 4302.921022 4444.147455 0.982648321 1.15382276 1.085307473 1.118313528 1.33683712 0.960099142 0.981734395 0.99290906 0.968221929 1 12.11769097 -7.283253514 23.99713271 0.991806144 1.091129312 0.18342938 0.102257649 646.6624674 711373.6008 0.017893492 0.02047218 5.21E-08 7.283253514 0.099323168 RESGEEFR ddPTM_HeLa_Curcumin_4h_R1 2 RESGEEFR 8 1 D6REW6;A0A3B3IRQ7;P30533 D6REW6 LRPAP1 Alpha-2-macroglobulin receptor-associated protein 0 0 ; ; 150.36 0.0027853 9104100 3205.1 2665.9 2731.9 2777.4 2904.3 3537.2 2433.6 2616.99 3344 3202.8 FALSE FALSE TRUE 2951.412953 2896.328517 2833.146617 2765.907855 2869.668119 2803.544848 2501.880266 3414.898204 2977.171566 3314.097062 0.890563221 0.873941971 0.854877381 0.834588669 0.865897427 0.845945304 0.754920637 1.030415869 0.898335659 1 11.69440014 -8.64711592 0.561627974 1.005622945 0.856388511 0.109285908 0.071229377 0.648753271 0.396029498 0.046603334 0.015844378 2.25E-09 8.64711592 -0.149234434 RESPSPAPKPR ddPTM_HeLa_Curcumin_4h_R1 1 RESPSPAPKPR 11 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 0 0 75.566 0.012776 2549800 884.45 847.8 964.53 989.36 967.03 1114.8 857.62 840.78 912.27 814.3 FALSE FALSE TRUE 814.4448492 921.0800543 1000.27633 985.2662905 955.4987988 883.5779136 881.682509 1097.129952 812.1962634 842.5968644 0.966588987 1.093144412 1.187135121 1.169321098 1.133992825 1.048636603 1.046387123 1.302081693 0.963920349 1 9.718698737 -7.126169073 3.996444501 0.984362153 1.139243651 0.546358967 0.069173006 0.136695727 3.775916342 0.011342712 0.014037395 7.48E-08 7.126169073 0.154881498 RESTEIFQVASVTEGEESPPAICMEVFLFLWFIAPIYACVCRIFK ddPTM_HeLa_Curcumin_4h_R1 1 RESTEIFQVASVTEGEESPPAICMEVFLFLWFIAPIYACVCRIFK 45 2 Q86UQ5 Q86UQ5 GTSCR1 Gilles de la Tourette syndrome chromosomal region candidate gene 1 protein 0 0 15.206 0.018582 2011000 0 78.217 0 169.49 0 77.206 0 226.59 0 0 FALSE FALSE TRUE 0 84.97772895 0 168.7886953 0 61.19260531 0 295.6762479 0 0 0 RETELEVQ ddPTM_HeLa_Curcumin_4h_R1 1 RETELEVQ 8 1 F8WDU8 F8WDU8 SH3BP5 0 0 82.305 0.008923 0 1484.5 1206.9 1753.7 1171.2 1119.4 1302.6 856.84 887.66 1863.8 1399.1 FALSE FALSE TRUE 1367.000259 1311.219058 1818.693665 1166.353885 1106.051886 1032.426077 880.8806243 1158.303448 1659.345803 1447.718621 0.94424444 0.905714024 1.256248029 0.80564957 0.763996449 0.713140013 0.60846121 0.800088796 1.146179775 1 10.49956551 -6.015069486 22.38357741 0.988041271 0.721768979 0.644830951 0.112521937 82.61779471 122718.0957 0.014536626 0.024700668 9.66E-07 6.015069486 -0.266272292 REVLYDS(ph)EGLS(ph)GEER ddPTM_HeLa_Curcumin_4h_R1 2 REVLYDSEGLSGEER 15 1 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 2 0 REVLY(0.093)DS(0.907)EGLS(1)GEER;REVLY(0.006)DS(0.994)EGLS(1)GEER ; 93.768 0.0062757 13942000 7508.8 6348.6 6459.7 6757.3 7703.9 7987.8 6574.8 4621.3 6104.6 5366.3 TRUE FALSE FALSE 6914.470557 6897.344695 6699.102165 6729.340083 7612.036024 6331.040239 6759.271193 6030.313096 5434.940653 5552.778526 1.245227146 1.242142949 1.206441448 1.211886995 1.370851726 1.140157168 1.21727729 1.085999211 0.978778575 1 12.43899414 -9.235678457 0.859013786 0.993033915 1.219521689 0.614925285 0.070735197 0.359598238 0.454291724 0.053584458 0.013167396 5.81E-10 9.235678457 0.226487774 REVLYDS(ph)EGLSGEER ddPTM_HeLa_Curcumin_4h_R1 2 REVLYDSEGLSGEER 15 1 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 1 0 REVLYDS(0.978)EGLS(0.022)GEER;REVLY(0.006)DS(0.919)EGLS(0.075)GEER ; 73.346 0.011527 6670800 2291.48 1906.06 2242.81 2191.29 2105.3 2746.27 1507.96 1694.26 2363.61 1978.4 TRUE FALSE FALSE 2110.10694 2070.811333 2325.930512 2182.223023 2080.195673 2176.662645 1550.269299 2210.832075 2104.327896 2047.149253 1.030753834 1.011558552 1.136180231 1.065981398 1.016142653 1.063265242 0.757282009 1.079956467 1.027930862 1 10.99940057 GGLRPGS(ph)LDAEIDLLSSTLAELNGGR ddPTM_HeLa_Curcumin_4h_R1 2 GGLRPGSLDAEIDLLSSTLAELNGGR 26 1 Q15654 Q15654 TRIP6 Thyroid receptor-interacting protein 6 1 0 GGLRPGS(1)LDAEIDLLSSTLAELNGGR;GGLRPGS(0.998)LDAEIDLLS(0.001)ST(0.001)LAELNGGR ; 90.211 7.25E-06 189117000 3093 2851.9 3110.3 3304.9 3273.6 4660.8 2954.3 672.61 3866.7 3498.8 TRUE FALSE FALSE 2848.185786 3098.405528 3225.570454 3291.225199 3234.564458 3694.097542 3037.189707 877.6856927 3442.532684 3620.38304 0.78670841 0.855822573 0.890947289 0.90908204 0.893431558 1.020360968 0.838913914 0.242428959 0.950875266 1 11.82192663 -4.267155613 4.316966083 0.901213129 0.196642071 0.904597588 0.06484975 0.056413194 2.466611295 0.011804725 0.120593514 5.41E-05 4.267155613 -0.704571057 down TVDVPASLPT(ph)PPHNNQEELR ddPTM_HeLa_Curcumin_4h_R1 1 TVDVPASLPTPPHNNQEELR 20 0 Q8NEZ4;Q8NEZ4-3;H0Y765;H7BY37;Q8NEZ4-2;H7C2V8 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 1 0 TVDVPAS(0.006)LPT(0.994)PPHNNQEELR 75.319 0.0040542 3309800 1506.8 997.73 1382.4 1371.9 1362 1187 898.76 403.18 1448.7 1433 TRUE FALSE FALSE 1387.53519 1083.969335 1433.63296 1366.223441 1345.75904 940.8028198 923.9767867 526.107726 1289.781234 1482.796643 0.935755551 0.731030341 0.966843948 0.92138288 0.90758166 0.634478655 0.623131156 0.35480774 0.869830155 1 10.53410504 -4.267117861 0.641785412 0.95813827 6.77E-15 0.805638078 0.085802219 0.873055825 0.246214629 0.014725773 0.61155248 5.41E-05 4.267117861 -0.95813827 down RFDAQTGADR ddPTM_HeLa_Curcumin_4h_R1 2 RFDAQTGADR 10 1 P43686-2;P43686 P43686-2 PSMC4 26S protease regulatory subunit 6B 0 0 ; ; 126.19 0.0051194 5412100 1903.84 1572.84 1944.92 1913.9 2006.01 2464.9 2127.1 1577.65 2028.18 2069.32 FALSE FALSE TRUE 1753.149055 1708.789281 2017.000446 1905.980789 1982.089641 1953.651955 2186.780701 2058.668222 1805.693728 2141.228716 0.818758427 0.798041456 0.941982718 0.890134143 0.925678619 0.912397606 1.02127376 0.961442469 0.843297923 1 11.06422319 -4.818936499 7.738337382 0.905191584 0.991116662 0.289203125 0.059668504 0.287732072 33.36140037 0.010787651 0.032880064 1.52E-05 4.818936499 0.085925078 RFDDAVVQSDMK ddPTM_HeLa_Curcumin_4h_R1 6 RFDDAVVQSDMK 12 1 P11142;E9PKE3;E9PNE6;P11142-2;E9PN89;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PPY6;E9PN25 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 ;;;;; ;;;;; 174.21 1.42E-07 240327000 30315.2 24390.8 26632.2 26333.5 28900.8 34746.9 26322.2 24290.7 28539.8 25426.7 FALSE FALSE TRUE 27915.71993 26499.03207 27619.21276 26224.53895 28556.17684 27540.00126 27060.73009 31696.82261 25409.05534 26310.27593 1.061019656 1.007174236 1.049750023 0.996741312 1.085362119 1.046739355 1.028523234 1.204731668 0.965746441 1 14.68333876 -4.260709447 24.77032269 1.032116527 1.204731728 0.710315828 0.033938395 20.03509452 679736.9211 0.004094567 0.0330383 5.49E-05 4.260709447 0.172615201 RFDEILEASDGIMVAR ddPTM_HeLa_Curcumin_4h_R1 10 RFDEILEASDGIMVAR 16 1 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BR70 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ;;;;;;;;; ;;;;;;;;; 205.66 2.99E-10 169719820 13226.98 11671.96 12828.11 12465.25 12047.78 20272.45 14780.31 12739.5 14832.84 12929.26 FALSE FALSE TRUE 12180.05058 12680.83221 13303.53104 12413.6721 11904.11809 16067.71535 15195.00572 16623.7149 13205.71456 13378.55082 0.910416288 0.947847968 0.994392533 0.927878682 0.889791297 1.201005667 1.135773666 1.242564694 0.987081092 1 13.70763423 -5.254041812 24.99282532 0.952641227 1.187380594 0.875780705 0.041755908 156.845475 529904.0878 0.006508417 0.016234573 5.57E-06 5.254041812 0.234739368 RFDGK(ac)LQSESTNNGK ddPTM_HeLa_Curcumin_4h_R1 1 RFDGKLQSESTNNGK 15 2 P42285;H0Y8U3 P42285 SKIV2L2 Superkiller viralicidic activity 2-like 2 0 1 RFDGK(1)LQSESTNNGK 149.59 0.00025171 7691000 4408.4 3783.8 3530 3726.5 3552.4 5422.2 4684.4 5030.5 4422.8 4260.4 FALSE TRUE FALSE 4059.470488 4110.854812 3660.824905 3711.08073 3510.03995 4297.574599 4815.831657 6564.276292 3937.629905 4408.448583 0.920838797 0.932494671 0.830411161 0.84181105 0.796207528 0.974849659 1.092409623 1.489021856 0.893200824 1 12.10605532 -4.265169123 1.965986078 0.929916764 1.654384553 0.88051109 0.065643643 0.231106063 0.936986018 0.011334531 0.301004397 5.43E-05 4.265169123 0.724467789 SAEPAEALVLACK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 SAEPAEALVLACKR 14 1 Q96CW6 Q96CW6 SLC7A6OS Probable RNA polymerase II nuclear localization protein SLC7A6OS 0 1 SAEPAEALVLACK(1)R 158.56 0.00018699 2087800 421.93 280.87 393.37 330.22 440.35 527.97 337.63 523.19 464.37 283.52 FALSE TRUE FALSE 388.5337953 305.1471513 407.9486382 328.8536371 435.0991139 418.4630706 347.1029891 682.7082225 413.4297728 293.3722989 1.324371104 1.040136211 1.390549277 1.120943042 1.483095423 1.426389172 1.183148479 2.327105269 1.409232482 1 8.196588844 -2.25927391 1.289853514 1.190344722 199.9999988 0.733418691 0.184629753 97.10004502 1.158287622 0.02764149 56133.57956 0.005504604 2.25927391 198.809654 RFELYFQGPSSNKPR ddPTM_HeLa_Curcumin_4h_R1 2 RFELYFQGPSSNKPR 15 2 P33993;P33993-2;C9J8M6 P33993 MCM7 DNA replication licensing factor MCM7 0 0 ; ; 92.65 0.0032194 23392000 7491 6303.7 6433.7 6354.7 8712.4 11916.8 9741.3 8788.2 9880.4 7135.5 FALSE FALSE TRUE 6898.079446 6848.563739 6672.138582 6328.405935 8608.51032 9445.12135 10014.61466 11467.68172 8796.54484 7383.458094 0.934261339 0.927555036 0.903660385 0.85710596 1.165918491 1.279227325 1.356358299 1.553158639 1.19138549 1 12.85008096 -5.122682165 1.298083925 0.95283156 1.500641539 0.794961797 0.098978513 0.110991268 0.325618624 0.010452177 0.052438984 7.54E-06 5.122682165 0.547809979 RFIGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 RFIGSPR 7 1 K7ERJ3;P23443-4;P23443-3;P23443-5;P23443-2;P23443 K7ERJ3 RPS6KB1 Ribosomal protein S6 kinase beta-1 1 0 RFIGS(1)PR;RFIGS(1)PR;RFIGS(1)PR ;; 91.265 0.011713 16242200 6778.2 4596.2 6322 5059.4 6210.7 6816.9 5181.2 4031.8 5398.2 5320.9 TRUE FALSE FALSE 6241.698318 4993.475048 6556.298881 5038.465543 6136.641459 5402.998098 5326.570528 5261.07726 4806.030966 5505.800879 1.133658564 0.906947991 1.190798401 0.915119463 1.114577442 0.981328278 0.967446997 0.955551676 0.872903156 1 12.42673672 -5.087836537 7.149071896 1.053829674 0.96455355 0 0.102648912 0.332023107 23.34304886 0.011754386 0.030329069 8.17E-06 5.087836537 -0.089276123 RFPEAEALS(ph)PEQAAHYLR ddPTM_HeLa_Curcumin_4h_R1 2 RFPEAEALSPEQAAHYLR 18 1 Q2NKX8 Q2NKX8 ERCC6L DNA excision repair protein ERCC-6-like 1 0 RFPEAEALS(1)PEQAAHYLR;RFPEAEALS(1)PEQAAHYLR ; 98.957 0.00076099 9158000 2433.34 2124.61 2397.77 2302.47 2324.16 3198.95 1781.6 1262.05 2771.81 2257.23 TRUE FALSE FALSE 2240.738571 2308.251821 2486.633465 2292.942989 2296.44591 2535.45171 1831.586901 1646.843235 2467.749378 2335.668574 0.95935639 0.988261711 1.064634552 0.981707342 0.983207093 1.085535738 0.784180993 0.705084297 1.056549463 1 11.18961986 -4.630857871 5.373182535 0.992500606 0.724341796 0.850372433 0.044998235 0.048179766 2.036753111 0.005703412 0.022501277 2.34E-05 4.630857871 -0.26815881 RFPGYDSESK ddPTM_HeLa_Curcumin_4h_R1 1 RFPGYDSESK 10 1 P46777;A0A2R8Y6J3 P46777 RPL5 60S ribosomal protein L5 0 0 141.89 5.82E-06 11919000 6421.3 4305.9 5172.3 5865.7 6055.9 6869.8 5423.5 5058.5 5728.1 5245.6 FALSE FALSE TRUE 5913.047329 4678.082809 5363.989988 5841.429288 5983.687348 5444.926041 5575.668813 6600.813364 5099.741761 5427.88421 1.089383469 0.861861202 0.988228522 1.076189001 1.102397751 1.003139682 1.027226926 1.216093253 0.939545054 1 12.40617423 -4.260838425 23.86352919 1.030297462 1.216093349 0.404418213 0.071300154 20.88688658 828996.6218 0.009523787 0.075580504 5.48E-05 4.260838425 0.185795887 RFPSIVYEDPY(ph)QVS(ph)LQY(ph)MEK ddPTM_HeLa_Curcumin_4h_R1 1 RFPSIVYEDPYQVSLQYMEK 20 1 S4R404;Q96M34 S4R404 C3orf30 Uncharacterized protein C3orf30 3 0 RFPS(0.046)IVY(0.318)EDPY(0.881)QVS(0.787)LQY(0.967)MEK 43.534 0.015434 4783200 935.56 826.46 861.72 801.9 689.23 1016.4 517.93 777.8 1003 729.13 TRUE FALSE FALSE 861.5094388 897.8955198 893.6561012 798.5819503 681.0113824 805.5871828 532.4617219 1014.947639 892.9734094 754.4672132 1.141877902 1.19010542 1.184486331 1.058471377 0.902638803 1.067756383 0.705745343 1.345250823 1.183581465 1 9.559314397 -5.984409283 23.19834475 1.089361757 0.987424053 0.092893605 0.161196621 201.8523702 300342.9515 0.022089918 0.040027443 1.04E-06 5.984409283 -0.101937704 RFPT(ph)DYASTS(ph)EDEFGSNR ddPTM_HeLa_Curcumin_4h_R1 1 RFPTDYASTSEDEFGSNR 18 1 H0Y2V6;Q5SW79;Q5SW79-3 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 2 0 RFPT(0.789)DY(0.151)AS(0.187)T(0.187)S(0.685)EDEFGS(0.002)NR 71.176 0.0064313 0 1031.9 645.65 739.44 942.39 928.38 894.23 683.98 764.98 995.22 780.85 TRUE FALSE FALSE 950.2240261 701.457109 766.8442969 938.4906399 917.3096748 708.756618 703.170638 998.2188805 886.0468559 807.9844794 1.176042425 0.868156663 0.949082954 1.161520628 1.135306059 0.877190882 0.870277407 1.235443138 1.096613708 1 9.65818377 -7.290995651 24.95695043 1.083131131 1.010934978 0.068512033 0.128901734 1656.908307 1399069.231 0.02332943 0.02667985 5.12E-08 7.290995651 -0.072196153 RFPTDYAST(ph)SEDEFGSNR ddPTM_HeLa_Curcumin_4h_R1 1 RFPTDYASTSEDEFGSNR 18 1 H0Y2V6;Q5SW79;Q5SW79-3 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 0 RFPTDYAS(0.001)T(0.974)S(0.025)EDEFGSNR 151.22 4.14E-05 6693100 1607 1047.6 1406.7 1815.9 1739.6 1241.2 1073.6 1101 1686.3 1533.5 TRUE FALSE FALSE 1479.804254 1138.149876 1458.833539 1808.386287 1718.856406 983.7611288 1103.722327 1436.689832 1501.317109 1586.789011 0.932577831 0.717266044 0.919362013 1.139651381 1.083229336 0.619969714 0.695569681 0.905406971 0.946135308 1 10.6318946 -5.26096717 24.99999971 0.964253975 0.735840878 0.401830306 0.124236767 32.62177051 1727014.528 0.018239566 0.043555614 5.48E-06 5.26096717 -0.228413097 RFS(ph)DQAGPAIPTSNSYSK ddPTM_HeLa_Curcumin_4h_R1 1 RFSDQAGPAIPTSNSYSK 18 1 E7ETY4;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E9PC69;Q7KZI7-14 E7ETY4 MARK2 Serine/threonine-protein kinase MARK2 1 0 RFS(1)DQAGPAIPTSNSYSK 70.994 0.0063096 13252000 600.17 479.98 643.04 767.23 811.81 909.32 816.75 713.75 654.48 579.83 TRUE FALSE FALSE 552.6659112 521.4673325 666.8716281 764.0554055 802.129696 720.7167819 839.6658068 931.3690893 582.6851814 599.9790493 0.921142016 0.869142569 1.111491524 1.273470143 1.336929509 1.201236581 1.399491879 1.55233602 0.97117588 1 9.228768314 -6.309835417 1.927540072 0.954611543 1.362597527 0.828210057 0.089116096 0.105754126 0.767014153 0.014967377 0.025798524 4.90E-07 6.309835417 0.407985984 TITLVKS(ph)PISVPGGSALISNLGK ddPTM_HeLa_Curcumin_4h_R1 1 TITLVKSPISVPGGSALISNLGK 23 1 P51610-2;P51610;A6NEM2;P51610-4 P51610-2 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 0 T(0.003)IT(0.003)LVKS(0.941)PIS(0.053)VPGGSALISNLGK 99.171 3.25E-05 68165000 3738.9 2945.9 3144.6 3910.5 3011 5362.1 4829 11536 4236.9 3614.4 TRUE FALSE FALSE 3442.96212 3200.530469 3261.141642 3894.319387 2975.095792 4249.940017 4964.488743 15053.27329 3772.12267 3740.000131 0.920578075 0.85575678 0.871962975 1.041261832 0.79548013 1.136347558 1.327403361 4.024939243 1.008588914 1 11.86882261 -4.226469573 2.784260273 0.95196456 4.754045118 0.988897426 0.096994961 0.034924468 0.338936846 0.01348882 0.313177039 5.94E-05 4.226469573 3.802080558 up RFS(ph)FCCSPEPEAEAEAAAGPGPCER ddPTM_HeLa_Curcumin_4h_R1 1 RFSFCCSPEPEAEAEAAAGPGPCER 25 1 Q13501;E7EMC7;E3W990;D6RBF1;C9J6J8 Q13501 SQSTM1 Sequestosome-1 1 0 RFS(0.57)FCCS(0.43)PEPEAEAEAAAGPGPCER 84.971 4.37E-05 37204000 1748.3 1339.4 1608.3 1816.7 1786.9 1853.4 1242.8 1358.2 2033.2 1689.3 TRUE FALSE FALSE 1609.92021 1455.171768 1667.905013 1809.182977 1765.592385 1468.983948 1277.669623 1772.308928 1810.163047 1748.003049 0.921005379 0.832476676 0.954177405 1.034999897 1.010062531 0.840378367 0.730931004 1.01390494 1.035560577 1 10.77149199 -13.52287875 0.125044866 1.294823638 0.870010253 0.149761595 0.091195263 147.0565805 1.316122217 10.91854096 0.391876632 3.00E-14 13.52287875 -0.424813385 RFS(ph)FSQR ddPTM_HeLa_Curcumin_4h_R1 1 RFSFSQR 7 1 Q92614;A0A0D9SFK2;Q92614-3;Q92614-4 Q92614 MYO18A Unconventional myosin-XVIIIa 1 0 RFS(0.954)FS(0.046)QR 81.525 0.015206 9114800 2220.5 1755.1 1656.2 2225.1 2011.1 2582.8 2227.1 701.13 2152.8 2041.3 TRUE FALSE FALSE 2044.745082 1906.803023 1717.580229 2215.893126 1987.118946 2047.098166 2289.586432 914.9013094 1916.643226 2112.235023 0.968048091 0.902741884 0.813157726 1.04907508 0.940766025 0.969162117 1.083963862 0.433143708 0.907400552 1 11.04455465 -4.254189618 24.99889115 0.972939477 0.433143455 0.819081086 0.073947228 243.4455315 839437.1781 0.009555493 0.13107804 5.57E-05 4.254189618 -0.539796022 SRS(ph)PESQVIGENTK ddPTM_HeLa_Curcumin_4h_R1 1 SRSPESQVIGENTK 14 1 O95218-2 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 S(0.081)RS(0.883)PES(0.036)QVIGENTK 82.265 0.0074459 22299000 2545.8 2295.4 2061 2899.5 2821.6 3448.5 3358.9 7162 2587.3 2442.8 TRUE FALSE FALSE 2344.297244 2493.804148 2137.382473 2887.502637 2787.954263 2733.242227 3453.141694 9345.66083 2303.479663 2527.687118 0.927447557 0.986595267 0.845588229 1.142349706 1.102966519 1.081321421 1.366127029 3.69731711 0.911299364 1 11.30360218 -4.226000268 2.664970485 0.986853715 4.38322156 0.987810541 0.089334816 0.041516537 0.354987762 0.013279008 0.32324794 5.94E-05 4.226000268 3.396367845 up RFS(ph)PSQVPIQTR ddPTM_HeLa_Curcumin_4h_R1 1 RFSPSQVPIQTR 12 1 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 0 RFS(0.986)PS(0.014)QVPIQTR 77.324 0.012934 37092000 1059.9 814.03 970.05 1131.2 865.79 1035.6 865.46 701.49 1123.1 1071.5 TRUE FALSE FALSE 976.0077966 884.391126 1006.000906 1126.519394 855.4660197 820.8048864 889.7424783 915.3710717 999.8987399 1108.734545 0.880289877 0.797658132 0.907341537 1.016040674 0.771569735 0.740307849 0.802484672 0.825599848 0.901837815 1 10.11469828 -13.52287874 0.065525045 1.622945093 0.596196517 0.276569429 0.075449813 170.1453175 0.87031542 16.54919361 2.685122337 3.00E-14 13.52287874 -1.026748576 RFS(ph)SGGEEDDFDR ddPTM_HeLa_Curcumin_4h_R1 1 RFSSGGEEDDFDR 13 1 A0A0C4DGA7;O94929-2;O94929-3;O94929 A0A0C4DGA7 ABLIM3 Actin-binding LIM protein 3 1 0 RFS(0.993)S(0.007)GGEEDDFDR 169.15 0.00030182 56683000 1149.5 828.62 1060.4 988.7 1248.2 1586.7 1175.4 1028.7 1476.4 1241.5 TRUE FALSE FALSE 1058.515862 900.2422205 1099.699357 984.6090214 1233.31603 1257.600534 1208.378561 1342.345894 1314.442614 1284.642033 0.823977291 0.700772821 0.856035634 0.766446213 0.960046456 0.978950168 0.940634457 1.044918242 1.023197576 1 10.32715069 -5.54573694 24.97190854 0.881693118 0.981095026 0.26448123 0.094730416 317.364639 346710.6043 0.015540785 0.031083155 2.85E-06 5.54573694 0.099401907 RFS(ph)SSDFSDLSNGEELQETCSSSLR ddPTM_HeLa_Curcumin_4h_R1 1 RFSSSDFSDLSNGEELQETCSSSLR 25 1 P23497;E9PHV6;P23497-7;P23497-6;P23497-2;P23497-3;P23497-4;H7C1G8;H7C4B4 P23497 SP100 Nuclear autoantigen Sp-100 1 0 RFS(0.538)S(0.194)S(0.194)DFS(0.071)DLS(0.004)NGEELQETCSSSLR 98.446 2.26E-05 0 497.18 328.05 320.65 480.75 453.5 400.61 222.6 186.3 660.84 314.57 TRUE FALSE FALSE 457.8276784 356.4051802 332.5335711 478.7607839 448.0923087 317.5189702 228.8455569 243.1020124 588.3475053 325.5012841 1.406531098 1.094942471 1.021604483 1.47084146 1.376622246 0.975476859 0.703055773 0.746854235 1.807512087 1 8.346519425 -4.970858316 3.849228607 1.207477632 0.731450375 0.45553356 0.243177872 0.131684045 4.258095886 0.026973001 0.08558589 1.07E-05 4.970858316 -0.476027257 RFSFCCS(ph)PEPEAEAEAAAGPGPCER ddPTM_HeLa_Curcumin_4h_R1 2 RFSFCCSPEPEAEAEAAAGPGPCER 25 1 Q13501;E7EMC7;E3W990;D6RBF1;C9J6J8 Q13501 SQSTM1 Sequestosome-1 1 0 RFS(0.188)FCCS(0.812)PEPEAEAEAAAGPGPCER;RFS(0.205)FCCS(0.795)PEPEAEAEAAAGPGPCER ; 95.742 5.44E-06 113912000 2352.7 1724.95 2291.9 2277.3 2288.68 2488 1396.29 1391.49 2556.4 1857.72 TRUE FALSE FALSE 2166.481312 1874.046992 2376.83983 2267.877136 2261.388986 1971.960754 1435.466139 1815.748895 2275.969316 1922.275632 1.127039888 0.974910653 1.236471914 1.179787695 1.17641245 1.025847034 0.746753543 0.944583006 1.183997382 1 10.9085995 -4.912408665 6.000947527 1.084829179 0.848591651 0.549656192 0.095463394 0.125504826 6.863492572 0.013595684 0.041838021 1.22E-05 4.912408665 -0.236237528 RFT(ph)PPS(ph)TALSPGK ddPTM_HeLa_Curcumin_4h_R1 1 RFTPPSTALSPGK 13 1 C9JWM1;A8MZI9;H9KVB1;Q01196-6;Q01196-5;Q01196-7;Q01196-3;Q01196-4;Q01196;Q01196-9;Q01196-10;Q01196-2;Q01196-8 C9JWM1 RUNX1 Runt-related transcription factor 1 2 0 RFT(1)PPS(0.843)T(0.129)ALS(0.028)PGK 82.121 0.015011 10983000 5969.3 5415.9 5262.7 6092.9 6038 6205.2 5085.7 2140.6 5467.9 4975.9 TRUE FALSE FALSE 5496.823606 5884.026263 5457.740292 6067.689194 5966.000794 4918.171573 5228.391055 2793.259086 4868.08505 5148.812155 1.067590629 1.142792956 1.059999885 1.178463889 1.158714013 0.955205089 1.015455778 0.542505534 0.945477307 1 12.33002392 -4.00996598 1.849985789 1.05897929 0.041560803 0.801410365 0.077144745 0.626675962 1.21779583 0.010769287 1.373694569 9.77E-05 4.00996598 -1.017418487 RFTDEESR ddPTM_HeLa_Curcumin_4h_R1 2 RFTDEESR 8 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;H0YF00;Q9NYF8-2;Q9NYF8 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 0 ; ; 134.77 0.0061956 9365200 2545.1 1974.39 2287.6 1806.67 2310.94 2999.7 2030 2102.18 2520.1 1920.6 FALSE FALSE TRUE 2343.652649 2145.047474 2372.380468 1799.194478 2283.38355 2377.528406 2086.956337 2743.125005 2243.651335 1987.340707 1.179290819 1.079355677 1.193746226 0.905327643 1.148964313 1.196336591 1.050125089 1.380299309 1.128971659 1 10.95662351 -13.52287875 0.020780633 3.42E-07 1.935808847 0.129493649 0.11430237 3309.582726 5.544890286 345.6391523 192.0878139 3.00E-14 13.52287875 1.935808505 RFVNVVPTFGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 RFVNVVPTFGKK 12 2 E9PR30;P62861 E9PR30 FAU 40S ribosomal protein S30 0 1 ; RFVNVVPTFGK(1)K;RFVNVVPTFGK(1)K 156 4.81E-06 23550000 17569.4 10508.3 14623.3 12528.6 13203 17345.8 14849.7 15175.8 14219.5 13936.1 FALSE TRUE FALSE 16178.76345 11416.59063 15165.25236 12476.75997 13045.56285 13748.08555 15266.34262 19802.83156 12659.65643 14420.37844 1.121937508 0.791698406 1.051654256 0.865217236 0.904661615 0.953378971 1.058664492 1.37325325 0.87790043 1 13.81582141 -4.272199306 3.698388935 1.008933046 1.408537744 0.541183472 0.106675775 0.167169452 4.262691296 0.015409674 0.179782981 5.34E-05 4.272199306 0.399604699 RGAAGDWGER ddPTM_HeLa_Curcumin_4h_R1 2 RGAAGDWGER 10 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 0 ; ; 108.9 0.0019578 18616720 2410.27 1841.29 2018.7 2190.28 2062.04 2592.89 2227 2311.18 2304.9 2071.06 FALSE FALSE TRUE 2219.494586 2000.442903 2093.514798 2181.217202 2037.45152 2055.095386 2289.483626 3015.848143 2052.058237 2143.029181 1.035680991 0.933465079 0.976895143 1.017819646 0.95073438 0.958967523 1.068339921 1.407282817 0.957550301 1 11.06543578 -4.272881553 3.235778194 1.00073358 1.459788164 0.925525 0.035957252 0.063950348 1.067615743 0.00524418 0.072366229 5.33E-05 4.272881553 0.459054585 RGADDDRPSWR ddPTM_HeLa_Curcumin_4h_R1 1 RGADDDRPSWR 11 2 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 73.841 0.013604 6756300 1537.5 1195.8 1578.5 1300.8 1086.1 1677.2 1042.1 1257.7 1301.6 1525 FALSE FALSE TRUE 1415.805253 1299.159624 1637.000599 1295.417634 1073.148967 1329.329814 1071.338521 1641.16694 1158.817736 1577.993636 0.897218607 0.823298392 1.037393663 0.820927033 0.680071796 0.842417728 0.678924488 1.040033941 0.734361476 1 10.62387567 -6.107075369 7.295189055 0.944249854 0.796928513 0.043401503 0.127068831 0.24276893 14.66461003 0.015536291 0.025870817 7.81E-07 6.107075369 -0.14732134 RGAEDDRGPWR ddPTM_HeLa_Curcumin_4h_R1 1 RGAEDDRGPWR 11 2 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 67.704 0.016549 9254500 1752 1309.2 1573.9 1636.9 1449.5 2203.3 1529.3 1574 2140.8 1895.7 FALSE FALSE TRUE 1613.327351 1422.361414 1632.230119 1630.126942 1432.215659 1746.310744 1572.208042 2053.905354 1905.959596 1961.575434 0.822465108 0.72511176 0.832101631 0.831029444 0.730135398 0.890259285 0.801502718 1.047069268 0.971647362 1 10.9377971 -9.082512595 0.913063282 0.99750348 0.829581006 0.325771417 0.085813446 0.468971783 0.722736218 0.049973468 0.015778214 8.27E-10 9.082512595 -0.167922474 RGAPS(ph)SPATGVLPSPQGK ddPTM_HeLa_Curcumin_4h_R1 2 RGAPSSPATGVLPSPQGK 18 1 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 1 0 RGAPS(0.447)S(0.447)PAT(0.087)GVLPS(0.018)PQGK;RGAPS(0.466)S(0.466)PAT(0.061)GVLPS(0.007)PQGK ; 64.318 0.0098412 91772000 5310.3 4390.7 5129.2 5376.9 4845.7 6889 6244 7942.2 6196.4 5683 TRUE FALSE FALSE 4889.984152 4770.212543 5319.292664 5354.651812 4787.918192 5460.143745 6419.189835 10363.74022 5516.670423 5880.483827 0.831561534 0.811193889 0.904567179 0.910580144 0.814204806 0.928519473 1.09160913 1.762395837 0.938132063 1 12.52171914 -4.227915161 2.18463895 0.901662204 2.037222551 0.95443145 0.057048834 0.138756497 0.690004952 0.010775644 0.314857685 5.92E-05 4.227915161 1.135560347 RGAYGGGYGGYDDYNGYNDGYGFGSDR ddPTM_HeLa_Curcumin_4h_R1 4 RGAYGGGYGGYDDYNGYNDGYGFGSDR 27 1 P31943;G8JLB6;E9PCY7;H0YB39;H0YBD7 P31943 HNRNPH1 "Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed" 0 0 ;;; ;;; 145.83 1.43E-08 61282800 6941.22 6053.22 5766.25 5872.62 5616.14 7641.08 7060.55 6258.94 7895.91 6362.34 FALSE FALSE TRUE 6391.815113 6576.433364 5979.952298 5848.320654 5549.171199 6056.233875 7258.650031 8167.261993 7029.748428 6583.430841 0.970894244 0.998937108 0.908333731 0.888339347 0.842899596 0.919920634 1.102563421 1.240578384 1.067794072 1 12.6846239 -4.518236907 3.24810129 0.960769962 1.229792199 0.688034145 0.062558539 0.111695721 2.274643969 0.008861437 0.054845339 3.03E-05 4.518236907 0.269022238 RGDDWNDR ddPTM_HeLa_Curcumin_4h_R1 2 RGDDWNDR 8 1 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;A0A087X0F4;C9JUL9 Q9BXP5-5;C9JUL9 SRRT Serrate RNA effector molecule homolog 0 0 ; ; 122.13 0.011148 4531200 939.44 1043.76 985.46 973.22 1023.05 1206.04 657.05 651.94 1357.27 922.98 FALSE FALSE TRUE 865.0823327 1133.977963 1021.982014 969.1930735 1010.850797 955.8937091 675.4850546 850.7135048 1208.380877 955.0534863 0.905794644 1.187344981 1.070078304 1.014805021 1.058423231 1.000879765 0.707274581 0.890749594 1.265249427 1 9.899437721 -4.777574402 24.98268383 0.993384822 0.799012104 0.33159691 0.121121903 152.2478615 235734.1468 0.013302877 0.040086533 1.67E-05 4.777574402 -0.194372719 RGDDWNDREWDR ddPTM_HeLa_Curcumin_4h_R1 1 RGDDWNDREWDR 12 2 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;C9JUL9 Q9BXP5-5;C9JUL9 SRRT Serrate RNA effector molecule homolog 0 0 105.13 0.0027077 50076000 2447.2 2152.2 2515.7 2326 2228.7 3299.9 2602.1 2315.4 2602.7 2035.1 FALSE FALSE TRUE 2253.501538 2338.226578 2608.934055 2316.375628 2202.124208 2615.463542 2675.107923 3021.354801 2317.190322 2105.819574 1.070130398 1.110364158 1.238916234 1.0999877 1.045732614 1.242016921 1.270340516 1.434764326 1.100374577 1 11.04016612 -1 0.281994391 1.019634885 4.005224712 0.70938707 0.067539238 16.64677646 0.212296309 0.028248469 24.88002953 0.1 1 2.985589827 RGDEEEFFEIR ddPTM_HeLa_Curcumin_4h_R1 1 RGDEEEFFEIR 11 1 Q5TGL8 Q5TGL8 PXDC1 PX domain-containing protein 1 0 0 152.96 0.00070367 3866900 1346.2 944.97 1001.4 1286.6 1174.2 1500.9 670.63 868.51 1193.7 1230 FALSE FALSE TRUE 1239.646849 1026.648996 1038.512765 1281.27639 1160.198432 1189.596421 689.4460729 1133.314701 1062.754096 1272.742408 0.973996656 0.80664319 0.815964612 1.006705192 0.911573641 0.934671787 0.541701187 0.890450961 0.835011146 1 10.31372475 -1.541992589 0.175220086 1.029845543 5.45E-18 0.026560318 0.128126399 40.68352161 0.515002421 0.160735177 10.71570086 0.028708296 1.541992589 -1.029845543 RGDIIGVQGNPGK ddPTM_HeLa_Curcumin_4h_R1 2 RGDIIGVQGNPGK 13 1 Q15046;Q15046-2;H3BVA8;J3KRL2;H3BPV7 Q15046 KARS Lysine--tRNA ligase 0 0 ; ; 135.04 0.00023502 4724800 7027.4 6391.4 6193.1 6878.6 6452.5 8090.4 5584.4 5745.9 6814.8 6584 FALSE FALSE TRUE 6471.173875 6943.844136 6422.621734 6850.138176 6375.558152 6412.359842 5741.083234 7497.798459 6067.23349 6812.79351 0.949856159 1.01923596 0.942729546 1.00548155 0.935821428 0.941223278 0.842691508 1.100546853 0.890564712 1 12.73403077 -5.74126037 24.94533677 0.978369119 0.946054567 0 0.068808219 560.7782407 693231.0933 0.00834115 0.016665044 1.81E-06 5.74126037 -0.032314552 RGDLPFVVPR ddPTM_HeLa_Curcumin_4h_R1 4 RGDLPFVVPR 10 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ;;; ;;; 169.58 5.57E-13 165462000 12908.8 8932.2 11028.3 10845.6 11144 12992.8 10748.2 11557.5 12628.2 11035.2 FALSE FALSE TRUE 11887.05486 9704.259567 11437.0185 10800.72378 11011.11508 10297.94682 11049.76556 15081.32855 11242.91805 11418.67238 1.041018996 0.849858832 1.001606677 0.945882623 0.964307821 0.901851501 0.96769267 1.320760247 0.984608165 1 13.4791073 -4.259279039 24.89893394 0.988257494 1.320760368 0.771238521 0.05703113 76.69331413 883860.3393 0.008811914 0.077973807 5.50E-05 4.259279039 0.332502874 RGDS(ph)ESEEDEQDS(ph)EEVR ddPTM_HeLa_Curcumin_4h_R1 2 RGDSESEEDEQDSEEVR 17 1 Q9NZ63 Q9NZ63 C9orf78 Uncharacterized protein C9orf78 2 0 RGDS(0.969)ES(0.031)EEDEQDS(1)EEVR;RGDS(0.994)ES(0.008)EEDEQDS(0.999)EEVR ; 164.69 0.00017764 45213000 3078.9 2927.8 3034 2914 2815.9 3760 2918.7 2599.49 3091.7 3109.7 TRUE FALSE FALSE 2835.201816 3180.865986 3146.442709 2901.94264 2782.322232 2980.133616 3000.590867 3392.062534 2752.548245 3217.761844 0.8811099 0.988533689 0.977835795 0.901851281 0.864676246 0.926151083 0.932508685 1.054168301 0.855423235 1 11.65184184 -9.65211385 1.496729368 0.999922663 0.930166772 0 0.069659945 0.570342662 2.301921205 0.039161414 0.008879369 2.23E-10 9.65211385 -0.069755891 RGEAHLAVNDFELAR ddPTM_HeLa_Curcumin_4h_R1 4 RGEAHLAVNDFELAR 15 1 Q02790 Q02790 FKBP4 "Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed" 0 0 ;;; ;;; 142.39 8.06E-05 41148600 11731.6 10185.1 10955.8 11050.5 11492.1 17138.8 10323.7 9979.7 13456.5 11139.4 FALSE FALSE TRUE 10803.03148 11065.45466 11361.83159 11004.77596 11355.06421 13584.01969 10613.35524 13022.46459 11980.35562 11526.49332 0.937234871 0.960001828 0.985714499 0.954737547 0.985127384 1.178504104 0.920779195 1.129785463 1.039375574 1 13.49266605 -5.494949109 24.88005963 0.969143405 1.064301428 0.287487446 0.067377727 566.2057614 504382.5736 0.008302712 0.018523639 3.20E-06 5.494949109 0.095158024 RGEDVETSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 RGEDVETSKK 10 2 O60869-2;O60869-3;O60869 O60869-2 EDF1 Endothelial differentiation-related factor 1 0 1 ; RGEDVETSK(1)K;RGEDVETSK(1)K 171.67 3.16E-13 6564400 3932.9 2938.8 2981.8 3022 3010.8 5278 3345.2 4523.7 4153.1 3101.2 FALSE TRUE FALSE 3621.606815 3192.816777 3092.308131 3009.495765 2974.898176 4183.283305 3439.057309 5902.955305 3697.515321 3208.966469 1.128589797 0.994967323 0.963646134 0.93783958 0.927058043 1.303623252 1.071702476 1.839519161 1.152244922 1 11.647893 -2.031008661 1.216361373 1.0392759 199.9999933 0.814189328 0.112268754 111.8765596 0.847488055 0.015927312 61366.88403 0.009310893 2.031008661 198.9607174 RGEGDAPFSEPGTT(ph)STQRPSSPETATK ddPTM_HeLa_Curcumin_4h_R1 1 RGEGDAPFSEPGTTSTQRPSSPETATK 27 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 RGEGDAPFSEPGT(0.048)T(0.19)S(0.19)T(0.19)QRPS(0.19)S(0.19)PET(0.002)AT(0.001)K 86.08 1.26E-05 327090000 6115 4845.5 5532.9 5500.5 6315.5 6421.1 6020.6 4452.3 5464.8 4536.4 TRUE FALSE FALSE 5630.991297 5264.323429 5737.954141 5477.740388 6240.191787 5089.291479 6189.521832 5809.785774 4865.325112 4694.039562 1.199604567 1.121491065 1.222391517 1.166956587 1.329386279 1.084202937 1.318591748 1.23769425 1.03649001 1 12.19661429 -13.52287875 0.173391104 0.103297376 1.267444385 0.563586672 0.069946551 27.01426305 0.303317673 8.15293873 0.09677237 3.00E-14 13.52287875 1.164147009 RGEGDAPFSEPGTTSTQRPS(ph)SPETATK ddPTM_HeLa_Curcumin_4h_R1 1 RGEGDAPFSEPGTTSTQRPSSPETATK 27 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 RGEGDAPFSEPGT(0.04)T(0.113)S(0.04)T(0.049)QRPS(0.377)S(0.377)PET(0.003)AT(0.001)K 101.3 2.77E-07 857830000 4102.3 4096.7 4306.6 4222.3 4659.2 4738.4 4263 3740 3811.6 3209.8 TRUE FALSE FALSE 3777.598626 4450.800493 4466.206384 4204.829241 4603.642083 3755.602427 4382.608307 4880.308783 3393.477016 3321.340311 1.137371745 1.340061564 1.344700021 1.266003736 1.38607961 1.130749058 1.319530038 1.469379325 1.021719155 1 11.69754984 -7.626245232 1.142766191 1.036602716 1.319491524 0.668296484 0.087273054 0.184232828 0.493884279 0.020090711 0.020048701 2.36E-08 7.626245232 0.282888808 RGEK(ac)GEVVETVEDVIVR ddPTM_HeLa_Curcumin_4h_R1 1 RGEKGEVVETVEDVIVR 17 2 Q9H0E9-4;Q9H0E9-2;H7C128;H7C179;H7C127;B5MCW3;Q9H0E9 Q9H0E9-4 BRD8 Bromodomain-containing protein 8 0 1 RGEK(1)GEVVETVEDVIVR 161.19 0.00030123 1747300 679.75 544.74 682.23 424.97 493.04 865.3 738.96 875.06 683.96 584.48 FALSE TRUE FALSE 625.9470702 591.8248983 707.514044 423.2115867 487.16082 685.8270261 759.6932288 1141.861766 608.9312992 604.7906365 1.034981417 0.978561609 1.169849533 0.699765441 0.805503245 1.133990814 1.256125976 1.888028182 1.00684644 1 9.240291993 -4.216727034 1.668085455 0.991145981 2.271959089 0.822795856 0.128780752 0.339845411 0.826723799 0.018718806 0.720216007 6.07E-05 4.216727034 1.280813108 RGEK(ac)GEVVETVEDVIVRK ddPTM_HeLa_Curcumin_4h_R1 1 RGEKGEVVETVEDVIVRK 18 3 Q9H0E9-4;Q9H0E9-2;H7C128;H7C179;H7C127;B5MCW3;Q9H0E9 Q9H0E9-4 BRD8 Bromodomain-containing protein 8 0 1 RGEK(1)GEVVETVEDVIVRK 79.804 0.0042053 1354300 457.04 493.73 387.3 567.35 416.32 579.86 454.18 557.4 462.07 493.19 FALSE TRUE FALSE 420.8648017 536.4058212 401.6536787 565.002456 411.3556559 459.5904996 466.9230684 727.348694 411.382077 510.3283158 0.824694199 1.051099468 0.787049565 1.107135228 0.806060811 0.900578089 0.914946426 1.425256392 0.806112583 1 8.995281882 -4.261082118 24.06885234 0.919950451 1.425256639 0.680014018 0.105694265 7.188361084 483939.9745 0.013438094 0.105308897 5.48E-05 4.261082118 0.505306188 GSSGENNNPGSPT(ph)VSNFR ddPTM_HeLa_Curcumin_4h_R1 1 GSSGENNNPGSPTVSNFR 18 0 D6R8Z7;D6RDZ7;D6RD37;D6RAX8;D6RBL1;D6RDZ9;D6RCK9;Q99576-3 D6R8Z7 TSC22D3 1 0 GSSGENNNPGS(0.472)PT(0.524)VS(0.004)NFR 271.73 1.08E-53 23208000 1715.2 1109.6 1080.5 1536.6 1527.3 2019.1 2119.8 2595 1769.5 1422.5 TRUE FALSE FALSE 1579.44011 1205.50888 1120.544281 1530.241956 1509.087945 1600.3159 2179.275883 3386.203554 1575.390277 1471.931769 1.073038943 0.818997799 0.761274608 1.039614735 1.025243137 1.087221523 1.480554961 2.300516658 1.07028757 1 10.52349508 -4.225854284 1.507149765 0.996028604 2.896408333 0.942522532 0.10051091 0.219234739 0.422381892 0.016096251 0.633376725 5.94E-05 4.225854284 1.900379728 up RGES(ph)LDNLDSPR ddPTM_HeLa_Curcumin_4h_R1 7 RGESLDNLDSPR 12 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 RGES(1)LDNLDSPR;RGES(1)LDNLDSPR;RGES(1)LDNLDSPR;RGES(1)LDNLDSPR;RGES(1)LDNLDSPR;RGES(1)LDNLDSPR;RGES(1)LDNLDSPR ;;;;;; 137.73 0.0020488 1030176000 12447.63 10112.03 11051.72 12381.4 11960.24 11797 9884.5 14154.3 12903.9 11455.75 TRUE FALSE FALSE 11462.38695 10986.06881 11461.30647 12330.16905 11817.62195 9350.16922 10161.83247 18469.88091 11488.37445 11853.83646 0.966976977 0.926794363 0.966885827 1.040183833 0.996944912 0.788788444 0.857261065 1.55813529 0.969169306 1 13.53306644 -4.255109957 24.99862829 0.964262637 1.558135554 0.865863403 0.071966706 201.4089885 795461.2154 0.010523515 0.132284277 5.56E-05 4.255109957 0.593872918 RGESLDNLDS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 RGESLDNLDSPR 12 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 RGESLDNLDS(1)PR 127.05 0.0013332 71584000 3141.1 2626.1 2725.5 2722.4 3098.9 5184.3 5304.8 2157.2 3221 2399.2 TRUE FALSE FALSE 2892.478621 2853.088382 2826.509428 2711.13543 3061.947641 4109.017741 5453.638411 2814.920349 2867.664359 2482.572021 1.165113679 1.149246974 1.138540757 1.092067181 1.233377165 1.655145432 2.196769465 1.133872583 1.155118294 1 11.27761986 -5.320588599 3.305915068 1.093908546 1.724204681 0.495317815 0.244336104 0.124532165 2.701363634 0.031931458 0.080029269 4.78E-06 5.320588599 0.630296135 RGFGFVEFEDPRDADDAVYELDGK ddPTM_HeLa_Curcumin_4h_R1 2 RGFGFVEFEDPRDADDAVYELDGK 24 2 G3V5K8;B4DJK0;B4DUA4;Q13243-2;Q13243 G3V5K8 SRSF5 Serine/arginine-rich splicing factor 5 0 0 ; ; 71.001 0.00036277 7720700 1255.37 1090.79 1297.09 1300.17 1195.92 2197.1 1402.49 1329.3 1617.51 1225.88 FALSE FALSE TRUE 1156.00614 1185.073027 1345.161296 1294.790241 1181.659435 1741.396694 1441.840095 1734.597451 1440.0732 1268.479239 0.91133233 0.934247082 1.060451961 1.020742162 0.931555992 1.372822385 1.136668264 1.367462232 1.135275341 1 10.30888419 -5.268377901 24.97463747 0.966546433 1.276752694 0.673102298 0.091510361 166.810739 600422.327 0.010411714 0.023755337 5.39E-06 5.268377901 0.310206261 TEAPAPASSTPQEPWPGPT(ph)APSPTSRPPWAVDPAFAER ddPTM_HeLa_Curcumin_4h_R1 1 TEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAER 38 1 Q9NR12-2;Q9NR12 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 0 TEAPAPASST(0.001)PQEPWPGPT(0.871)APS(0.123)PT(0.004)SRPPWAVDPAFAER 96.699 2.29E-14 20292000 1400.7 948.82 1244.5 1242.6 972.41 1679 1754.8 2510.7 1411.5 1079.9 TRUE FALSE FALSE 1289.833117 1030.831773 1290.622265 1237.45845 960.8146459 1330.756474 1804.034965 3276.200872 1256.661981 1117.426445 1.154289057 0.92250526 1.154995276 1.107418261 0.859845989 1.190911921 1.614455228 2.931916358 1.12460376 1 10.12596415 -4.223503209 1.772196024 1.058731213 3.682921132 0.971532222 0.097069957 0.112676545 0.322988457 0.014275506 0.509595953 5.98E-05 4.223503209 2.624189919 up RGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDR ddPTM_HeLa_Curcumin_4h_R1 1 RGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDR 32 1 P31942;P31942-3;P31942-4;P31942-5 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 0 63.128 0.0007541 61191000 936.58 781.88 884.22 886.09 966.68 1399.8 1191.6 981.07 1178.6 975.14 FALSE FALSE TRUE 862.4487047 849.4622232 916.989971 882.4235944 955.1529724 1109.465701 1225.033089 1280.193727 1049.310529 1009.026042 0.854733841 0.841863527 0.908787219 0.874530049 0.946608841 1.099541196 1.214074798 1.268742008 1.039924129 1 9.978747695 -5.011104468 1.833409764 0.916189238 1.259489765 0.830815713 0.058508321 0.114230981 0.722160613 0.009397235 0.040467549 9.75E-06 5.011104468 0.343300527 RGGGSGGGEES(ph)EGEEVDED ddPTM_HeLa_Curcumin_4h_R1 1 RGGGSGGGEESEGEEVDED 19 1 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 0 RGGGSGGGEES(1)EGEEVDED 128.82 0.00022418 131130000 8571 7164.7 7480.7 8107.7 8198.4 9964.9 7752.5 7112.9 9021.8 7027.9 TRUE FALSE FALSE 7892.596306 7783.984743 7757.941323 8074.152486 8100.639435 7898.067412 7970.014285 9281.590466 8032.131111 7272.119002 1.085322765 1.070387426 1.066806157 1.110288828 1.113931088 1.086075106 1.095968628 1.276325437 1.104510406 1 12.82816009 -1 0.167714736 1.003546615 1.748471906 0.468460635 0.048254135 29.8561664 0.311038795 0.065563627 5.589636531 0.1 1 0.744925291 RGS(ph)ASGSEPAGDSDR ddPTM_HeLa_Curcumin_4h_R1 2 RGSASGSEPAGDSDR 15 1 A0A0C4DG27;P50747 A0A0C4DG27 HLCS Biotin--protein ligase;Biotin--[methylmalonyl-CoA-carboxytransferase] ligase;Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase;Biotin--[methylcrotonoyl-CoA-carboxylase] ligase;Biotin--[acetyl-CoA-carboxylase] ligase 1 0 RGS(1)ASGSEPAGDSDR;RGS(0.992)AS(0.008)GSEPAGDSDR ; 141.22 0.00024765 20243100 3058 2731.5 3110.8 2548.4 3258.2 3761.7 3563.6 4860.6 3375.6 2990.4 TRUE FALSE FALSE 2815.956073 2967.598689 3226.088985 2537.855396 3219.348093 2981.481017 3663.585025 6342.574565 3005.305125 3094.316177 0.91004148 0.959048306 1.042585437 0.8201668 1.040406962 0.963534702 1.183972424 2.049749994 0.971234015 1 11.5954049 -4.223383513 2.250234825 0.958559642 2.39587728 0.965305401 0.06163748 0.084539497 0.450477692 0.008522474 0.248920225 5.98E-05 4.223383513 1.437317639 up RGGPNYQEGLR ddPTM_HeLa_Curcumin_4h_R1 2 RGGPNYQEGLR 11 1 P53396;P53396-2;P53396-3;K7EIE7 P53396 ACLY ATP-citrate synthase 0 0 ; ; 117.09 0.0011184 6408600 2938.35 1812.53 2220.3 2415.04 2514.59 2709.32 2271.12 2459.56 2919.73 2179.86 FALSE FALSE TRUE 2705.776497 1969.197017 2302.586271 2405.047204 2484.605157 2147.376492 2334.841515 3209.468522 2599.442924 2255.609973 1.199576403 0.87302195 1.020826428 1.066251361 1.101522509 0.95201587 1.035126437 1.42288275 1.152434577 1 11.13930191 -4.258771721 24.81666059 1.062538448 1.422882894 0.602919288 0.091065018 138.039132 1284066.302 0.014213536 0.130069177 5.51E-05 4.258771721 0.360344445 RGLDDDRGPWR ddPTM_HeLa_Curcumin_4h_R1 1 RGLDDDRGPWR 11 2 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 60.691 0.020132 6335800 2014.2 1100.5 1312.5 1374.9 1311.9 1690.5 1125.2 1149.4 1705 1473.4 FALSE FALSE TRUE 1854.773945 1195.622316 1361.142405 1369.211028 1296.256449 1339.871244 1156.770084 1499.846769 1517.965766 1524.60054 1.216563877 0.784220053 0.892786254 0.89807854 0.850226938 0.878834297 0.758736504 0.983763766 0.995648188 1 10.57421558 -7.256149206 24.99889612 1.102266276 0.862253905 0.557136964 0.083123248 224.6314414 1061503.698 0.015779228 0.019024566 5.54E-08 7.256149206 -0.240012371 RGLLYDS(ph)DEEDEERPAR ddPTM_HeLa_Curcumin_4h_R1 5 RGLLYDSDEEDEERPAR 17 2 P49736 P49736 MCM2 DNA replication licensing factor MCM2 1 0 RGLLYDS(1)DEEDEERPAR;RGLLYDS(1)DEEDEERPAR;RGLLYDS(1)DEEDEERPAR;RGLLYDS(1)DEEDEERPAR;RGLLYDS(1)DEEDEERPAR ;;;; 103.73 0.0011455 837493000 3942.25 3338.66 3937.31 3811.07 3753.04 4900.84 3777.76 3438.1 4522.01 4016.6 TRUE FALSE FALSE 3630.216753 3627.238894 4083.230172 3795.300802 3708.287449 3884.35054 3883.753778 4486.360863 4025.956817 4156.176551 0.873451045 0.872734555 0.982448681 0.913171218 0.892235304 0.934597097 0.934453513 1.079444246 0.968668382 1 12.02104122 -4.261270155 6.499665669 0.931669492 1.08240677 0.535418781 0.041695373 0.092998624 23.5532855 0.00733146 0.061323517 5.48E-05 4.261270155 0.150737278 RGLLYDS(ph)DEEDEERPARK ddPTM_HeLa_Curcumin_4h_R1 1 RGLLYDSDEEDEERPARK 18 3 P49736 P49736 MCM2 DNA replication licensing factor MCM2 1 0 RGLLYDS(1)DEEDEERPARK 58.366 0.015219 35447000 3032.6 3158.7 2726.8 2938.4 2877.1 3815.5 2601.6 2141.9 3732 3153.1 TRUE FALSE FALSE 2792.56651 3431.723953 2827.857607 2926.241679 2842.792462 3024.12229 2674.593894 2794.95545 3322.608937 3262.66999 0.855914487 1.051814607 0.866731118 0.896885584 0.871308612 0.926885741 0.819756182 0.856646691 1.018371134 1 11.67183736 -13.52287875 0.250534492 1.694580613 0.875476913 0.40240009 0.058508979 41.50544438 0.548799388 14.33943618 0.035403558 3.00E-14 13.52287875 -0.819103701 TFCPPPLPKPSSTTPTPLVSETGGNS(ph)PSDKVDNELK ddPTM_HeLa_Curcumin_4h_R1 1 TFCPPPLPKPSSTTPTPLVSETGGNSPSDKVDNELK 36 2 A0A3B3IRW6;Q2KHR3-2;Q2KHR3;H0YCQ7 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 0 TFCPPPLPKPSSTTPT(0.003)PLVS(0.003)ET(0.02)GGNS(0.735)PS(0.238)DKVDNELK 78.662 2.00E-08 45761000 1965.3 1509.4 1688.8 1783 1725.3 2362.2 1534.9 507.69 2134.9 1402.3 TRUE FALSE FALSE 1809.744431 1639.86581 1751.388414 1775.622418 1704.726924 1872.253093 1577.965163 662.4823439 1900.706811 1451.029821 1.24721381 1.130139289 1.206996844 1.223698089 1.174839345 1.290292636 1.087479486 0.456560116 1.309901964 1 10.50286145 -4.267047335 4.479247013 1.14877737 0.412997312 0.842046227 0.093861466 0.064097186 3.216595235 0.014933049 0.147316285 5.41E-05 4.267047335 -0.735780059 down RGNDPLTSS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 3 RGNDPLTSSPGR 12 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 0 RGNDPLTSS(1)PGR;RGNDPLT(0.043)S(0.236)S(0.721)PGR;RGNDPLT(0.012)S(0.1)S(0.887)PGR ;; 171.11 6.21E-05 850267000 4904.71 3956.68 4526.8 5120.5 4730.5 5338.7 5069.8 4909.5 5469.1 4776.8 TRUE FALSE FALSE 4516.497028 4298.677789 4694.56719 5099.312728 4674.091877 4231.39344 5212.044943 6406.383949 4869.153413 4942.793444 0.913753949 0.869685905 0.949780168 1.031666159 0.945637711 0.856073289 1.054473549 1.296105941 0.985101536 1 12.2711109 -4.344292148 3.121031818 0.950050859 1.319740736 0.800366815 0.05315423 0.101897737 1.561191733 0.007950371 0.081464266 4.53E-05 4.344292148 0.369689877 RGPCIIYNEDNGIIK ddPTM_HeLa_Curcumin_4h_R1 2 RGPCIIYNEDNGIIK 15 1 P36578;H3BM89 P36578 RPL4 60S ribosomal protein L4 0 0 ; ; 147.51 0.00070804 12911600 5836.2 4390.8 4647.9 5423.5 5013.4 6139.9 4571.6 5265.9 5953.6 5188.5 FALSE FALSE TRUE 5374.258612 4770.321187 4820.155263 5401.058994 4953.618479 4866.415529 4699.866792 6871.448669 5300.504975 5368.799989 1.001016731 0.888526523 0.897808686 1.006008606 0.922667726 0.906425186 0.875403591 1.27988539 0.987279278 1 12.39038394 RGPGT(ph)PGPVAR ddPTM_HeLa_Curcumin_4h_R1 1 RGPGTPGPVAR 11 1 Q8N6S5 Q8N6S5 ARL6IP6 ADP-ribosylation factor-like protein 6-interacting protein 6 1 0 RGPGT(1)PGPVAR 75.911 0.0088571 0 252.56 202.53 328.75 495.24 340.75 405.18 135.13 47.575 501.91 232.89 TRUE FALSE FALSE 232.5696095 220.0357907 340.9337642 493.1908281 336.6867788 321.1411007 138.9213841 62.08039849 446.8517287 240.9829102 0.965087563 0.913076328 1.414763246 2.046580099 1.39713965 1.332630187 0.576478158 0.257613282 1.854288042 1 7.912787028 -2.694820685 9.14073698 1.06042678 0.788444204 0 0.531874755 0 0 0.064474724 0 0.0020192 2.694820685 -0.271982576 RGPNYTSGYGTNSELS(ph)NPSETESER ddPTM_HeLa_Curcumin_4h_R1 2 RGPNYTSGYGTNSELSNPSETESER 25 1 B4DXZ6;P51114-3;P51114;E7EU85;E9PFF5;P51114-2 B4DXZ6;E7EU85 FXR1 Fragile X mental retardation syndrome-related protein 1 1 0 RGPNYTSGYGTNS(0.001)ELS(0.914)NPS(0.069)ET(0.012)ES(0.005)ER;RGPNYTSGYGTNSELS(0.492)NPS(0.408)ET(0.07)ES(0.03)ER ; 91.064 8.88E-06 36790800 3563.1 2915.1 3117.4 3173.1 2706 4355.7 2898.1 3276.4 4315.3 3668.4 TRUE FALSE FALSE 3281.076875 3167.068255 3232.933586 3159.970553 2673.732717 3452.278721 2979.412886 4275.359277 3841.922386 3795.876627 0.864379219 0.83434436 0.85169617 0.832474515 0.704378192 0.909481277 0.784907725 1.126316711 1.012130468 1 11.89021739 -8.935827087 0.758847535 1.000666623 0.854415826 0.227391239 0.102968755 0.772587514 0.818850675 0.06429313 0.02028389 1.16E-09 8.935827087 -0.146250797 RGPNYTSGYGTNSELSNPSET(ph)ESER ddPTM_HeLa_Curcumin_4h_R1 1 RGPNYTSGYGTNSELSNPSETESER 25 1 B4DXZ6;P51114-3;P51114;E7EU85;E9PFF5;P51114-2 B4DXZ6;E7EU85 FXR1 Fragile X mental retardation syndrome-related protein 1 1 0 RGPNYTSGYGTNS(0.002)ELS(0.262)NPS(0.262)ET(0.342)ES(0.131)ER 60.941 0.0022891 29492000 5131.2 3662.6 4541.4 5138.6 3969.8 5745.2 4250.3 4490.6 6557.9 5466.6 TRUE FALSE FALSE 4725.060106 3979.178824 4709.708279 5117.337835 3922.462728 4553.580758 4369.551979 5859.763268 5838.514777 5656.563943 0.835323379 0.703462184 0.832609394 0.904672498 0.693435585 0.805008271 0.772474602 1.035922749 1.032166318 1 12.46571024 -8.85121096 0.813851163 0.995704946 0.816523377 0.38965049 0.094545527 0.50096246 0.636571476 0.050634371 0.018601189 1.41E-09 8.85121096 -0.17918157 RGPPPPPR ddPTM_HeLa_Curcumin_4h_R1 1 RGPPPPPR 8 1 P38159;P38159-2;H0Y6E7;H3BT71 P38159 RBMX "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed" 0 0 80.229 0.012259 1984900 949.33 823.76 923.49 896.17 1237.8 1106.8 923.63 958.35 962.24 891.34 FALSE FALSE TRUE 874.1895288 894.9621438 957.7153518 892.461886 1223.040043 877.2372038 949.544572 1250.546503 856.6846794 922.3139987 0.947822032 0.970344313 1.03838319 0.96763346 1.326056034 0.951126411 1.02952419 1.355879348 0.928842759 1 9.849114185 -5.873621647 20.89680673 0.979124493 1.141465731 0.38195015 0.116824658 2.41636808 437.1868913 0.016001573 0.029005393 1.34E-06 5.873621647 0.162341238 RGQS(ph)PLPR ddPTM_HeLa_Curcumin_4h_R1 1 RGQSPLPR 8 1 H3BTS1;H3BN52;Q9BQ65-3;Q9BQ65-2;Q9BQ65 H3BTS1 USB1 U6 snRNA phosphodiesterase 1 0 RGQS(1)PLPR 81.017 0.014475 27179000 1824.8 1648.9 1721.3 1901.4 1577.4 2324.2 1582.6 1245.2 2071.4 1923.5 TRUE FALSE FALSE 1680.365154 1791.423569 1785.092892 1893.532511 1558.590535 1842.134721 1627.003497 1624.855748 1844.172602 1990.341482 0.844259726 0.9000584 0.896877701 0.951360622 0.783076949 0.925537018 0.817449423 0.816370338 0.926560904 1 10.95880026 -13.52287874 0.260268704 1.918999525 0.852359993 0.292281749 0.054956216 27.54509911 0.367417318 13.04982315 0.026821665 3.00E-14 13.52287874 -1.066639532 RGS(ph)ALGPDEAGGELER ddPTM_HeLa_Curcumin_4h_R1 1 RGSALGPDEAGGELER 16 1 R4GNF1;R4GN36;O75145-2;O75145 R4GNF1 PPFIA3 Liprin-alpha-3 1 0 RGS(1)ALGPDEAGGELER 62.165 0.01762 6500600 1261.6 1215.1 1069.3 1306.1 1271.9 1570.5 1353.4 1604.6 1124.4 1185.4 TRUE FALSE FALSE 1161.743029 1320.12783 1108.929199 1300.695704 1256.733423 1244.760597 1391.372762 2093.835153 1001.056133 1226.592562 0.947130339 1.076256184 0.904072985 1.06041382 1.024572839 1.014811793 1.1343398 1.707033956 0.816127673 1 10.26044039 -4.149399289 1.901360772 0.986999886 2.086769468 0.898687469 0.073079951 0.165687991 0.483944208 0.006864682 0.352322208 7.09E-05 4.149399289 1.099769582 AAAPPQPS(ph)PPPTK ddPTM_HeLa_Curcumin_4h_R1 1 AAAPPQPSPPPTK 13 0 J3KR72;P49848-4;P49848-2;P49848;P49848-3 J3KR72 TAF6 Transcription initiation factor TFIID subunit 6 1 0 AAAPPQPS(0.994)PPPT(0.006)K 86.756 0.015581 15551000 2391.2 2107 2193.9 2169.9 2093.8 2945.2 2717.7 3772.5 2775.1 2267.2 TRUE FALSE FALSE 2201.933997 2289.119691 2275.207864 2160.921529 2068.832803 2334.332321 2793.951348 4922.717884 2470.678473 2345.985031 0.93859678 0.97576057 0.969830512 0.921114798 0.881861041 0.995032914 1.190950202 2.098358608 1.053151849 1 11.19597809 -4.223198228 2.26037727 0.961612671 2.456794627 0.982914971 0.044636151 0.054635866 0.294546354 0.005766129 0.167902387 5.98E-05 4.223198228 1.495181956 up RGS(ph)DASDFDLLETQSACSDTSESSAAGGQGNSR ddPTM_HeLa_Curcumin_4h_R1 2 RGSDASDFDLLETQSACSDTSESSAAGGQGNSR 33 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 1 0 RGS(0.717)DAS(0.264)DFDLLET(0.018)QS(0.001)ACSDTSESSAAGGQGNSR;RGS(0.857)DAS(0.143)DFDLLETQSACSDTSESSAAGGQGNSR ; 111.69 1.35E-14 19497300 995.26 930.6 1042.35 1063.57 1209.23 1196.02 1036.3 1234.76 1002.63 829.69 TRUE FALSE FALSE 916.4841208 1011.036917 1080.980408 1059.169229 1194.810722 947.9519701 1065.375789 1611.23264 892.6439975 858.5216657 1.06751426 1.177648693 1.259118379 1.233712871 1.391707128 1.10416779 1.240942228 1.87675245 1.039745452 1 9.745710732 -1 0.347983429 1.03681918 8.497370027 0.652410971 0.141822181 24.404497 0.306167888 0.042196413 120.8156656 0.1 1 7.460550847 RNS(ph)VTPLASPEPTK ddPTM_HeLa_Curcumin_4h_R1 2 RNSVTPLASPEPTK 14 1 Q9H178;Q5W015;Q5VX20;A0A1W2PR17;Q16875-3;Q16875-2;Q16875;Q16875-4 Q9H178 PFKFB3 "6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase" 1 0 RNS(0.98)VT(0.02)PLASPEPTK;RNS(0.907)VT(0.093)PLASPEPTK ; 91.307 0.0057823 13548400 4256.5 3780.1 4466.4 3839.8 5252.8 6157.2 5240 9413.8 4426.3 4723.5 TRUE FALSE FALSE 3919.593534 4106.835 4631.928713 3823.911925 5190.163791 4880.127314 5387.020297 12284.02428 3940.745964 4887.641273 0.801939691 0.840248858 0.947681807 0.782363457 1.061895401 0.998462661 1.102171783 2.513282706 0.806267429 1 12.25492269 -4.222425987 2.756960441 0.910299135 2.909613801 0.963907746 0.092753941 0.073378936 0.684926276 0.01427 0.345212948 5.99E-05 4.222425987 1.999314666 up RGS(ph)GDTSISIDTEASIR ddPTM_HeLa_Curcumin_4h_R1 4 RGSGDTSISIDTEASIR 17 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3;Q32MZ4-4 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 0 RGS(0.986)GDT(0.01)S(0.004)ISIDTEASIR;RGS(0.925)GDT(0.071)S(0.004)ISIDTEASIR;RGS(0.991)GDT(0.006)S(0.001)IS(0.001)IDTEASIR;RGS(0.91)GDT(0.015)S(0.065)IS(0.01)IDTEASIR ;;; 103.85 0.0017401 14319000 3221.22 3002.62 2759.63 3201.79 2905.14 3342.4 3154.67 3356.91 3377.48 3321.38 TRUE FALSE FALSE 2966.257038 3262.153093 2861.904315 3188.541841 2870.498103 2649.148563 3243.18155 4380.416406 3006.978894 3436.797708 0.86308747 0.949183912 0.832724111 0.927765354 0.835224633 0.770818881 0.94366379 1.274563352 0.874936249 1 11.74684922 -4.270174488 4.755341502 0.909637162 1.293097993 0.747331694 0.06657139 0.079082246 4.976764137 0.010896044 0.098851423 5.37E-05 4.270174488 0.38346083 RGS(ph)GDTSSLIDPDTSLSELR ddPTM_HeLa_Curcumin_4h_R1 3 RGSGDTSSLIDPDTSLSELR 20 1 C9JSU1;Q9Y608-4;Q9Y608;Q9Y608-2;Q9Y608-5 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 0 RGS(0.993)GDT(0.005)S(0.001)S(0.001)LIDPDTSLSELR;RGS(0.811)GDT(0.15)S(0.035)S(0.004)LIDPDTSLSELR;RGS(0.998)GDT(0.002)SSLIDPDTSLSELR ;; 113.52 8.35E-05 406619600 6610.6 5662.4 6665.3 7282.1 7373.8 7403.6 6618.4 8958.2 6187.5 6189.3 TRUE FALSE FALSE 6087.364035 6151.832625 6912.321881 7251.9686 7285.872251 5868.009904 6804.094491 11689.51394 5508.74673 6404.377714 0.950500471 0.960566803 1.079312025 1.132345549 1.137639374 0.916249816 1.062413055 1.825238058 0.860153316 1 12.64484268 -4.263397834 4.496500755 1.001278503 1.878931648 0.890983222 0.085641609 0.040847457 2.081053281 0.011087063 0.112932358 5.45E-05 4.263397834 0.877653145 RIS(ph)TSDILSEK ddPTM_HeLa_Curcumin_4h_R1 1 RISTSDILSEK 11 1 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 0 RIS(0.972)T(0.026)S(0.002)DILSEK 110.44 0.010321 7181500 2046.3 1464.6 1871.2 2125 1578.7 2646.3 3101.8 5043.5 1886 1874.5 TRUE FALSE FALSE 1884.333196 1591.193498 1940.548318 2116.207313 1559.875034 2097.42755 3188.82816 6581.239933 1679.110519 1939.638735 0.97148668 0.8203556 1.000468944 1.091031683 0.804209055 1.081349589 1.644032005 3.393023563 0.865682092 1 10.92157226 -4.222273317 1.867072172 0.970600208 4.326525425 0.98482918 0.091610068 0.068996849 0.22519312 0.012029706 0.415237224 5.99E-05 4.222273317 3.355925216 up RGS(ph)IGENQGEEK ddPTM_HeLa_Curcumin_4h_R1 5 RGSIGENQGEEK 12 1 E7EX44;Q05682-3;Q05682-6;Q05682-2 E7EX44 CALD1 Caldesmon 1 0 RGS(1)IGENQGEEK;RGS(1)IGENQGEEK;RGS(1)IGENQGEEK;RGS(1)IGENQGEEK;RGS(1)IGENQGEEK ;;;; 144.88 0.00081938 760680000 22138.4 21034.9 20870.4 20802.8 21807.3 25352.4 22495.6 19963.9 20523.6 19540.5 TRUE FALSE FALSE 20386.12228 22853.06303 21643.87538 20716.72353 21547.26219 20094.02646 23126.76599 26050.80121 18272.21243 20219.53092 1.008239131 1.130246944 1.070443991 1.02458972 1.06566578 0.993792909 1.143783507 1.288397902 0.903691213 1 14.30346191 -4.44229495 2.454424966 1.022956328 1.303512756 0.678267543 0.056870656 0.13626462 1.2841829 0.006673993 0.067074272 3.61E-05 4.44229495 0.280556428 RGS(ph)IGENQIK ddPTM_HeLa_Curcumin_4h_R1 2 RGSIGENQIK 10 1 Q05682-5;Q05682-4;E9PGZ1;C9J813 Q05682-5 CALD1 Caldesmon 1 0 RGS(1)IGENQIK;RGS(1)IGENQIK ; 146.5 0.0016592 63064000 4966.4 4838.2 5578.5 5428.1 6833.1 6837.6 5747 4463.7 4703 4406.3 TRUE FALSE FALSE 4573.304199 5256.392449 5785.244117 5405.63996 6751.619745 5419.404684 5908.245353 5824.661582 4187.092666 4559.418597 1.003045477 1.152864633 1.268855665 1.185598524 1.480807169 1.188617489 1.29583306 1.277500948 0.918339165 1 12.15463415 -6.994121612 1.790230557 0.99898714 1.289531111 0.746134495 0.080339113 0.113147251 0.716761314 0.012474242 0.016415473 1.01E-07 6.994121612 0.29054397 RGS(ph)IGENQIKDEK ddPTM_HeLa_Curcumin_4h_R1 1 RGSIGENQIKDEK 13 2 Q05682-5;Q05682-4;E9PGZ1;C9J813 Q05682-5 CALD1 Caldesmon 1 0 RGS(1)IGENQIKDEK 160.03 0.0046162 16330000 4984.7 4811.5 4335.4 5003.8 4676.7 6229.2 4781.6 4339 5270.7 4656.8 TRUE FALSE FALSE 4590.155735 5227.38462 4496.073738 4983.095601 4620.933407 4937.193702 4915.758827 5661.941126 4692.517397 4818.623453 0.952586518 1.084829448 0.933061855 1.0341326 0.958973751 1.024606664 1.020158324 1.175012155 0.973829444 1 12.23440535 RGS(ph)IGENQVEVMVEEK ddPTM_HeLa_Curcumin_4h_R1 2 RGSIGENQVEVMVEEK 16 1 Q05682 Q05682 CALD1 Caldesmon 1 0 RGS(1)IGENQVEVMVEEK;RGS(1)IGENQVEVMVEEK ; 136.77 0.00019613 28493000 20960.8 18959.6 17651.5 17564.8 18862.4 22283.6 19065.6 17606.3 20085 18158.5 TRUE FALSE FALSE 19301.73056 20598.38334 18305.68012 17492.12151 18637.4782 17661.73017 19600.52942 22974.37982 17881.72575 18789.50652 1.027261176 1.096270587 0.97425018 0.930951619 0.991908871 0.939978394 1.043163608 1.22272396 0.951686822 1 14.19763956 -4.287668513 3.700941368 1.004738203 1.240568191 0.675426989 0.047576283 0.10883669 2.758307672 0.006396142 0.067133369 5.16E-05 4.287668513 0.235829987 RGS(ph)LEMSSDGEPLSR ddPTM_HeLa_Curcumin_4h_R1 4 RGSLEMSSDGEPLSR 15 1 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 0 RGS(0.967)LEMS(0.017)S(0.017)DGEPLSR;RGS(0.998)LEMS(0.001)S(0.001)DGEPLS(0.001)R;RGS(0.989)LEMS(0.005)S(0.005)DGEPLSR;RGS(0.994)LEMS(0.003)S(0.003)DGEPLSR ;;; 195.23 2.25E-06 42874500 6805.3 4910.12 4559.23 6203.4 6449.4 7846.7 7040.9 6614 6094.81 6398.14 TRUE FALSE FALSE 6266.653324 5334.528894 4728.199075 6177.731974 6372.495117 6219.205969 7238.448704 8630.578153 5426.224591 6620.474889 0.946556468 0.805762273 0.714178236 0.933125203 0.962543507 0.939389708 1.093342823 1.303619196 0.819612593 1 12.69271899 -4.37108668 1.855428177 0.936721944 1.375113747 0.645819001 0.092589212 0.365882347 1.521783406 0.014237122 0.256060061 4.26E-05 4.37108668 0.438391803 RGS(ph)LGEEGSEPPPPPPLPLAR ddPTM_HeLa_Curcumin_4h_R1 3 RGSLGEEGSEPPPPPPLPLAR 21 1 Q14934-2;Q14934-9;Q14934-3;Q14934-4;Q14934-5;Q14934-6;Q14934-7;Q14934;Q14934-8;Q14934-10;Q14934-18;Q14934-11;Q14934-12;Q14934-13;Q14934-14;Q14934-15;Q14934-16;Q14934-17 Q14934-2 NFATC4 "Nuclear factor of activated T-cells, cytoplasmic 4" 1 0 RGS(0.999)LGEEGS(0.001)EPPPPPPLPLAR;RGS(0.843)LGEEGS(0.157)EPPPPPPLPLAR;RGS(0.939)LGEEGS(0.061)EPPPPPPLPLAR ;; 139.12 2.09E-05 46014800 3316.28 2912.73 3276.46 3419.26 3042.8 2912.1 2738.6 2539.3 4276.23 3810.48 TRUE FALSE FALSE 3053.792939 3164.493402 3397.88849 3405.112008 3006.516597 2308.097634 2815.437745 3313.520881 3807.138268 3942.893896 0.774505482 0.802581425 0.86177528 0.863607314 0.762515218 0.585381624 0.714053642 0.840377897 0.965569546 1 11.94503917 -13.52287875 0.178519244 1.989729345 0.713060722 0.560250181 0.07546736 31.2602934 0.357074638 10.73910751 0.114022299 3.00E-14 13.52287875 -1.276668623 RGS(ph)LSNAGDPEIVK ddPTM_HeLa_Curcumin_4h_R1 4 RGSLSNAGDPEIVK 14 1 O43847;O43847-2;F5H7V1 O43847 NRD1 Nardilysin 1 0 RGS(0.925)LS(0.075)NAGDPEIVK;RGS(0.756)LS(0.244)NAGDPEIVK;RGS(0.999)LS(0.001)NAGDPEIVK;RGS(0.963)LS(0.037)NAGDPEIVK ;;; 204.17 7.68E-09 148662000 15897.5 13863.9 16229.3 16918 17943.3 17877.6 16766.8 15404.1 13947.4 13523.2 TRUE FALSE FALSE 14639.1961 15062.23374 16830.77213 16847.9978 17729.33787 14169.58424 17237.23128 20100.73918 12417.40511 13993.13019 1.046170221 1.07640203 1.202788218 1.204019227 1.267002995 1.012610048 1.231835268 1.436471962 0.887392952 1 13.7724311 -1 0.175383857 0.966842262 2.513063079 0.613319648 0.094891179 30.34984573 0.324676823 0.123357076 12.48831897 0.1 1 1.546220817 RGS(ph)MFYDEDGDLAHEFYEETIVTK ddPTM_HeLa_Curcumin_4h_R1 2 RGSMFYDEDGDLAHEFYEETIVTK 24 1 O75896 O75896 TUSC2 Tumor suppressor candidate 2 1 0 RGS(0.498)MFY(0.45)DEDGDLAHEFY(0.048)EET(0.004)IVTK;RGS(0.727)MFY(0.252)DEDGDLAHEFY(0.02)EET(0.001)IVTK ; 46.839 0.0092597 5661200 3106.33 2186.32 2922.19 3010.89 2668.36 4744.18 3206.11 3056.13 2981.52 2778.56 TRUE FALSE FALSE 2860.460703 2375.295759 3030.488932 2998.431735 2636.54155 3760.18359 3296.064818 3987.929968 2654.454715 2875.114753 0.994903142 0.826156854 1.054041036 1.042891151 0.917021328 1.307837743 1.14641157 1.387050713 0.923251746 1 11.48940382 -5.257732905 24.99984659 0.987532243 1.267031179 0.735597885 0.085710304 122.5939739 826880.856 0.010848236 0.026529088 5.52E-06 5.257732905 0.279498936 RGS(ph)PSAAFTFPDTDDFGK ddPTM_HeLa_Curcumin_4h_R1 4 RGSPSAAFTFPDTDDFGK 18 1 H7C055;Q9ULT0;Q9ULT0-4;Q9ULT0-3 H7C055 TTC7A Tetratricopeptide repeat protein 7A 1 0 RGS(0.765)PS(0.235)AAFTFPDTDDFGK;RGS(0.939)PS(0.06)AAFT(0.001)FPDTDDFGK;RGS(0.656)PS(0.344)AAFTFPDTDDFGK;RGS(0.965)PS(0.035)AAFTFPDTDDFGK ;;; 139.16 0.00010086 58479000 11192.5 8876.06 9173.5 10212.9 9535 10237.89 7004.05 5887.42 10141.08 9057.96 TRUE FALSE FALSE 10306.60181 9643.267075 9513.47798 10170.64173 9421.301353 8114.436209 7200.564793 7682.467256 9028.628896 9372.723436 1.099637889 1.028864998 1.015017465 1.085131957 1.005182903 0.865750095 0.768246801 0.819662215 0.963287667 1 13.1942526 -5.202843025 2.504839989 1.046481845 0.79507581 0.850763586 0.040822614 0.071704874 0.872988663 0.005961029 0.017805965 6.27E-06 5.202843025 -0.251406034 RCS(ph)DNTEVEVSNLENK ddPTM_HeLa_Curcumin_4h_R1 1 RCSDNTEVEVSNLENK 16 1 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 0 RCS(0.944)DNT(0.056)EVEVSNLENK 124.2 0.00031816 11975000 3562.9 3725.3 3470.8 3496.3 3962.5 5149 3215.1 1151.6 3552.6 3105.8 TRUE FALSE FALSE 3280.892705 4047.298332 3599.430901 3481.833237 3915.249775 4081.039359 3305.307053 1502.717539 3162.888668 3213.726319 1.020899846 1.259378656 1.120017868 1.08342556 1.218289732 1.269877691 1.028496743 0.4675935 0.984181089 1 11.65003136 -4.26678678 5.053752857 1.072214661 0.440848155 0.760002672 0.10661685 0.069159028 5.595007227 0.016913411 0.151029648 5.41E-05 4.26678678 -0.631366506 down RGS(ph)SGSVDETLFALPAASEPVIR ddPTM_HeLa_Curcumin_4h_R1 1 RGSSGSVDETLFALPAASEPVIR 23 1 Q9NQC3-5;Q9NQC3 Q9NQC3-5 RTN4 Reticulon-4 1 0 RGS(0.565)S(0.217)GS(0.217)VDETLFALPAASEPVIR 101.06 2.39E-05 5638500 693.62 578.01 856.75 869.73 932.53 1017.1 1142.7 908.04 1161.1 693.91 TRUE FALSE FALSE 638.7192451 627.9706088 888.5019087 866.1312877 921.4101888 806.1419949 1174.761087 1184.897216 1033.730235 718.0233208 0.889552228 0.874582469 1.237427647 1.206271806 1.283259418 1.122723972 1.636104361 1.650221074 1.439688942 1 9.487886892 -4.227944319 0.443901686 0.939170461 2.271036632 0.431164282 0.198889935 1.572323145 0.203521013 0.030332375 1.107132974 5.92E-05 4.227944319 1.331866171 RGS(ph)SPGSLEIPK ddPTM_HeLa_Curcumin_4h_R1 1 RGSSPGSLEIPK 12 1 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 0 RGS(0.787)S(0.201)PGS(0.012)LEIPK 116.78 0.0018254 15574000 7893.2 6696.6 7556.3 8130.1 8040.8 8610.9 7662.7 10044 7556.9 7286.8 TRUE FALSE FALSE 7268.444891 7275.424265 7836.343125 8096.4598 7944.918712 6824.902275 7877.694739 13106.36936 6727.926976 7540.015758 0.963982719 0.964908363 1.03930063 1.07379879 1.053700545 0.905157561 1.044784917 1.738241641 0.892296143 1 12.88035182 -4.263605462 4.621645727 0.992160953 1.783179201 0.940295186 0.056479493 0.025991358 1.471677176 0.00667271 0.066198573 5.45E-05 4.263605462 0.791018248 RGSDAS(ph)DFDLLETQSACSDTSESSAAGGQGNSR ddPTM_HeLa_Curcumin_4h_R1 1 RGSDASDFDLLETQSACSDTSESSAAGGQGNSR 33 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 1 0 RGS(0.136)DAS(0.601)DFDLLET(0.047)QS(0.184)ACS(0.02)DT(0.007)S(0.003)ES(0.001)SAAGGQGNSR 66.376 0.00052958 0 326.85 320.01 223.67 379.08 368.82 333.25 288.77 172.75 439.33 304.99 TRUE FALSE FALSE 300.9794776 347.6702385 231.959407 377.5114674 364.4220624 264.1301935 296.872109 225.4206798 391.1365981 315.5883798 0.953708998 1.101657288 0.735006172 1.196214726 1.154738532 0.836945244 0.940694043 0.714287009 1.239388467 1 8.301900275 -4.048087281 1.323643597 0.991428551 0.486997561 0.263221352 0.151753194 2.049104056 2.152192127 0.017874361 1.583816239 8.95E-05 4.048087281 -0.50443099 RGSDASDFDLLET(ph)QSACSDTSESSAAGGQGNSR ddPTM_HeLa_Curcumin_4h_R1 2 RGSDASDFDLLETQSACSDTSESSAAGGQGNSR 33 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 1 0 RGS(0.036)DAS(0.017)DFDLLET(0.919)QS(0.028)ACSDTSESSAAGGQGNSR;RGS(0.207)DAS(0.028)DFDLLET(0.57)QS(0.195)ACSDTSESSAAGGQGNSR ; 137.48 1.20E-17 39892000 1690.49 1351.24 1593.69 1702.46 1861.94 1911.34 1666.67 1917.46 1809.53 1340.51 TRUE FALSE FALSE 1556.685933 1468.035165 1652.753553 1695.415672 1839.737582 1514.906539 1713.432275 2502.084727 1611.029086 1387.092623 1.12226531 1.0583541 1.19152357 1.222280073 1.326326412 1.092145192 1.235268825 1.803833923 1.16144305 1 10.43784841 -1.158414275 0.865309981 1.088338495 199.9999229 0.781632829 0.099902941 178.9770366 0.599200009 0.017273974 69954.23143 0.069436165 1.158414275 198.9115844 AS(ph)SLNENVDHSALLK ddPTM_HeLa_Curcumin_4h_R1 1 ASSLNENVDHSALLK 15 0 Q96SB3 Q96SB3 PPP1R9B Neurabin-2 1 0 AS(0.912)S(0.088)LNENVDHSALLK 130.56 0.0003365 18645000 1978.7 1138 1627.1 1701.8 1886.6 3745.5 4302.4 17730 1906.1 1511.4 TRUE FALSE FALSE 1822.083807 1236.363649 1687.401757 1694.758403 1864.103527 2968.64108 4423.113765 23135.79538 1697.005599 1563.921038 1.165074044 0.790553755 1.078955853 1.083659828 1.191942229 1.898203943 2.828220645 14.79345493 1.085096727 1 10.61095196 -4.221637043 2.708620835 1.114650228 18.27507168 0.994765713 0.294702827 0.028439568 0.251849052 0.045886762 1.135968197 6.00E-05 4.221637043 17.16042145 up LSVGAVSSKPT(ph)T(ph)PTIATPQTVSVPNK ddPTM_HeLa_Curcumin_4h_R1 2 LSVGAVSSKPTTPTIATPQTVSVPNK 26 1 Q9HBM6 Q9HBM6 TAF9B Transcription initiation factor TFIID subunit 9B 2 0 LS(0.008)VGAVS(0.359)S(0.443)KPT(0.563)T(0.549)PT(0.044)IAT(0.015)PQT(0.011)VS(0.007)VPNK;LSVGAVS(0.003)S(0.012)KPT(0.923)T(0.923)PT(0.134)IAT(0.004)PQT(0.001)VSVPNK ; 80.835 0.00047854 16504000 2618 1892.77 1982.33 2342.3 2366.6 3225.9 3603.6 8737.9 2513.4 2065.24 TRUE FALSE FALSE 2410.782537 2056.372605 2055.796894 2332.608183 2338.379841 2556.811977 3704.707317 11402.04549 2237.686308 2137.006936 1.128111705 0.962267632 0.961998232 1.091530469 1.094231283 1.196445334 1.7335963 5.335521047 1.047112328 1 11.06137588 -4.220700379 2.499916982 1.059072762 6.550429735 0.996542761 0.075140211 0.02858271 0.201612432 0.012877536 0.346566686 6.02E-05 4.220700379 5.491356973 up RGSGDTS(ph)SLIDPDTSLSELRDIYDLK ddPTM_HeLa_Curcumin_4h_R1 1 RGSGDTSSLIDPDTSLSELRDIYDLK 26 2 C9JSU1;Q9Y608-4;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 0 RGS(0.031)GDT(0.29)S(0.334)S(0.334)LIDPDT(0.004)S(0.004)LS(0.003)ELRDIYDLK 66.201 0.00058227 87664000 1753.8 1548.2 1869.5 1730.5 1689.8 2025.8 1789.8 2626.7 1810 1829.7 TRUE FALSE FALSE 1614.984879 1682.019509 1938.785315 1723.33965 1669.650239 1605.626245 1840.016971 3427.568738 1611.447528 1893.281939 0.853008126 0.888414702 1.024034126 0.910239312 0.881881459 0.848065051 0.971866331 1.810384744 0.851139757 1 10.88667355 -4.262411018 4.953585524 0.923036451 1.85477372 0.954011817 0.059090235 0.027799199 2.07361408 0.009307091 0.088481449 5.46E-05 4.262411018 0.931737268 RGSIGENQIK(ac)DEK ddPTM_HeLa_Curcumin_4h_R1 1 RGSIGENQIKDEK 13 2 Q05682-5;Q05682-4;E9PGZ1;C9J813 Q05682-5 CALD1 Caldesmon 0 1 RGSIGENQIK(1)DEK 83.087 0.0071699 3235600 1323.5 1876 1152.7 1108.9 2101.2 3083.8 1930.9 2369.2 2760.1 1154.3 FALSE TRUE FALSE 1218.743578 2038.153081 1195.420076 1104.311666 2076.144562 2444.185118 1985.075857 3091.558174 2457.323935 1194.411839 1.020371315 1.706407299 1.000844128 0.924565237 1.73821499 2.046350378 1.661969341 2.588351917 2.057350618 1 10.22208466 -1 0.311889455 0.975519525 15.16224845 0.321960927 0.445273181 18.7202399 0.239193083 0.100129409 152.2572588 0.1 1 14.18672893 RGSIGENQIKDEK ddPTM_HeLa_Curcumin_4h_R1 2 RGSIGENQIKDEK 13 2 Q05682-5;Q05682-4;E9PGZ1;C9J813 Q05682-5 CALD1 Caldesmon 0 0 ; ; 119.39 0.00021489 8664300 4241.9 3940.6 3101.7 4754.2 4158.7 3839.3 3468 3852 4637.1 4262.1 FALSE FALSE TRUE 3906.149139 4281.207905 3216.651731 4734.52838 4109.110219 3042.985902 3565.302746 5026.457068 4128.421731 4410.207658 0.885706398 0.970749733 0.729365141 1.073538651 0.931727152 0.689986989 0.808420606 1.139732515 0.936105973 1 12.10663087 -9.321068162 0.672836578 1.013665501 0.89420144 0.02277873 0.134086368 2.20047012 1.460774871 0.157011744 0.02733576 4.77E-10 9.321068162 -0.119464062 RGSLEMS(ph)SDGEPLSR ddPTM_HeLa_Curcumin_4h_R1 1 RGSLEMSSDGEPLSR 15 1 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 0 RGS(0.091)LEMS(0.454)S(0.454)DGEPLSR 134.02 0.0010199 21532000 1949 1877 1882.1 1804.2 1612.2 2635.1 2597.4 2136.6 2207.7 2002.7 TRUE FALSE FALSE 1794.734593 2039.239516 1951.852282 1796.734698 1592.975568 2088.550556 2670.276053 2788.039504 1965.520833 2072.293676 0.866061898 0.984049481 0.941880152 0.867027062 0.76870165 1.007844873 1.288560634 1.345388222 0.948476008 1 11.01701275 -4.791189255 3.549768485 0.923307784 1.332607411 0.859467198 0.064713448 0.065785342 1.704482945 0.010594573 0.040245398 1.62E-05 4.791189255 0.409299627 RGSLGEEGS(ph)EPPPPPPLPLAR ddPTM_HeLa_Curcumin_4h_R1 1 RGSLGEEGSEPPPPPPLPLAR 21 1 Q14934-2;Q14934-9;Q14934-3;Q14934-4;Q14934-5;Q14934-6;Q14934-7;Q14934;Q14934-8;Q14934-10;Q14934-18;Q14934-11;Q14934-12;Q14934-13;Q14934-14;Q14934-15;Q14934-16;Q14934-17 Q14934-2 NFATC4 "Nuclear factor of activated T-cells, cytoplasmic 4" 1 0 RGS(0.13)LGEEGS(0.87)EPPPPPPLPLAR 77.39 0.00071509 13165000 449.72 344.36 463.51 374.38 399.73 489.9 445.18 287.59 694.51 636.48 TRUE FALSE FALSE 414.1241875 374.124944 480.6880883 372.8309148 394.9634808 388.2892177 457.6705527 375.2748671 618.3239906 658.5976326 0.628796957 0.568062995 0.729866104 0.56609817 0.599703766 0.589569714 0.69491679 0.569809013 0.938849397 1 9.363253516 -9.14211554 0.614415037 1.043349337 0.612343353 0.863782274 0.055517626 0.241783504 0.142478503 0.057062925 0.011718869 7.21E-10 9.14211554 -0.431005984 RGSPS(ph)AAFTFPDTDDFGK ddPTM_HeLa_Curcumin_4h_R1 1 RGSPSAAFTFPDTDDFGK 18 1 H7C055;Q9ULT0;Q9ULT0-4;Q9ULT0-3 H7C055 TTC7A Tetratricopeptide repeat protein 7A 1 0 RGS(0.036)PS(0.876)AAFT(0.087)FPDT(0.001)DDFGK 95.409 0.0032388 18336000 1696.6 1559 1488 1808.6 1680.6 1388.4 1007.5 928.97 1505.3 1550.4 TRUE FALSE FALSE 1562.31232 1693.753013 1543.146589 1801.116492 1660.559943 1100.43019 1035.767738 1212.208677 1340.172356 1604.276285 0.973842433 1.05577389 0.961895781 1.1226972 1.035083519 0.685935584 0.645629277 0.755610918 0.835375034 1 10.64770691 -5.258476173 24.90725759 1.00376696 0.690715638 0.776341468 0.074239872 57.55853811 483805.4688 0.007446457 0.018128842 5.51E-06 5.258476173 -0.313051322 RGSS(ph)GSVDETLFALPAASEPVIR ddPTM_HeLa_Curcumin_4h_R1 2 RGSSGSVDETLFALPAASEPVIR 23 1 Q9NQC3-5;Q9NQC3 Q9NQC3-5 RTN4 Reticulon-4 1 0 RGS(0.327)S(0.5)GS(0.172)VDETLFALPAASEPVIR;RGS(0.244)S(0.377)GS(0.377)VDET(0.002)LFALPAASEPVIR ; 111.95 5.00E-06 6746500 1237.8 1144.34 1164.24 1449.87 1210.11 1556.76 1552.83 1236.08 1283.05 978.74 TRUE FALSE FALSE 1139.826824 1243.251651 1207.387759 1443.870822 1195.680229 1233.870428 1596.398231 1612.955102 1142.302625 1012.751142 1.125475723 1.227598369 1.192186025 1.425691626 1.1806259 1.218335262 1.576298623 1.592647033 1.127920352 1 9.984063997 -1 0.187336529 0.9748891 3.730112827 0.706461725 0.102014254 18.24061373 0.202416666 0.110633034 14.56672596 0.1 1 2.755223727 RGSS(ph)PGSLEIPKDLPDILNK ddPTM_HeLa_Curcumin_4h_R1 1 RGSSPGSLEIPKDLPDILNK 20 2 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 0 RGS(0.25)S(0.482)PGS(0.268)LEIPKDLPDILNK 53.278 0.020075 12059000 1239.6 1046.7 1049.3 1340.8 1063.9 1389.8 1372.2 1378.5 1273.6 1613.4 TRUE FALSE FALSE 1141.484352 1137.172084 1088.187981 1335.252125 1051.213687 1101.539814 1410.700239 1798.798304 1133.889266 1669.46553 0.68374239 0.681159367 0.651818179 0.799808143 0.629670795 0.659815848 0.845001118 1.077469569 0.679192979 1 10.70517059 -9.316499467 1.029534649 1.00068046 0.741930464 0 0.160138613 0.474320428 0.896550619 0.089301678 0.023463774 4.83E-10 9.316499467 -0.258749995 RGSSAAASPGS(ph)PPPGR ddPTM_HeLa_Curcumin_4h_R1 4 RGSSAAASPGSPPPGR 16 1 Q86UX6 Q86UX6 STK32C Serine/threonine-protein kinase 32C 1 0 RGS(0.001)S(0.002)AAAS(0.367)PGS(0.63)PPPGR;RGSSAAAS(0.273)PGS(0.727)PPPGR;RGSSAAAS(0.009)PGS(0.991)PPPGR;RGS(0.009)S(0.009)AAAS(0.155)PGS(0.826)PPPGR ;;; 113.23 0.00064831 39543600 1661.97 1852.68 1827.5 1613.3 1709.61 1746.16 1222.57 1175.35 1800.42 2392.59 TRUE FALSE FALSE 1530.423321 2012.817404 1895.228758 1606.624592 1689.224017 1383.986733 1256.872024 1533.708804 1602.91843 2475.732324 0.618169947 0.813018994 0.765522484 0.648949233 0.682312866 0.559021151 0.507676865 0.619497023 0.647452237 1 11.27363962 -13.52287875 0.189814573 2.591643333 0.566000581 0.030154478 0.132445423 20.39170799 0.241015448 12.03286218 0.10032118 3.00E-14 13.52287875 -2.025642753 HAAFVT(ph)PDQK ddPTM_HeLa_Curcumin_4h_R1 1 HAAFVTPDQK 10 0 P10244-2;P10244 P10244-2 MYBL2 Myb-related protein B 1 0 HAAFVT(1)PDQK 90.434 0.018079 4244800 3844.5 3240 3035.4 3294.6 3288.6 4718.5 3097.2 873.59 3992.7 3245.7 TRUE FALSE FALSE 3540.203768 3520.051163 3147.894594 3280.967818 3249.385593 3739.829912 3184.099096 1139.943569 3554.710799 3358.487833 1.054106474 1.048105974 0.93729522 0.976918179 0.967514475 1.113545767 0.948075221 0.339421676 1.058425987 1 11.71359609 -4.266729544 4.046364211 1.018904843 0.283303512 0.944245846 0.049255795 0.034576558 1.197325984 0.00670291 0.07356116 5.41E-05 4.266729544 -0.735601332 down AVLFCLS(ph)EDKK ddPTM_HeLa_Curcumin_4h_R1 1 AVLFCLSEDKK 11 1 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 0 AVLFCLS(1)EDKK 142.1 0.0019296 21576000 1785 1265.8 1351.5 1409.4 1407.9 1978.3 2204.8 3408.9 1786.1 1313.8 TRUE FALSE FALSE 1643.715366 1375.210112 1401.587779 1403.568276 1391.111712 1567.97828 2266.660754 4448.257917 1590.169299 1359.454452 1.209099256 1.011589693 1.03099282 1.032449652 1.023286738 1.153387874 1.667331149 3.27209044 1.169711347 1 10.4088121 -4.220341658 1.909911062 1.078867998 4.107585786 0.989339864 0.068735693 0.07849446 0.270429813 0.012677826 0.434201398 6.02E-05 4.220341658 3.028717788 up RGT(ph)YLPQT(ph)YIIQEEMVVT(ph)EHVS(ph)DK ddPTM_HeLa_Curcumin_4h_R1 1 RGTYLPQTYIIQEEMVVTEHVSDK 24 1 Q9NQX7-2;Q9NQX7-3;Q9NQX7;B8ZZM6 Q9NQX7-2 ITM2C Integral membrane protein 2C;CT-BRI3 4 0 RGT(0.548)Y(0.509)LPQT(0.548)Y(0.394)IIQEEMVVT(1)EHVS(1)DK 41.256 0.014304 2967900 203.02 0 159.6 151.1 67.3 224.77 152.14 165.66 286.29 120.48 TRUE FALSE FALSE 186.9507528 0 165.5149164 150.4747882 66.49749146 178.1501683 156.4086389 216.1689714 254.8847033 124.666671 1.499604916 0 1.327659711 1.207016976 0.533402319 1.429011995 1.254614707 1.733975646 2.044529634 1 6.96193201 -4.182563103 1.504607861 1.114963352 2.041505849 0.10977398 0.523984893 2.109108388 3.752829582 0.064136057 3.054332558 6.57E-05 4.182563103 0.926542497 RGTGQS(ph)DDS(ph)DIWDDTALIK ddPTM_HeLa_Curcumin_4h_R1 3 RGTGQSDDSDIWDDTALIK 19 1 B4DP61;A0A1W2PRV5;E7EQZ4;Q16637-4;Q16637-2;Q16637-3;Q16637 B4DP61 SMN2;SMN1 Survival motor neuron protein 2 0 RGT(0.514)GQS(0.579)DDS(0.764)DIWDDT(0.143)ALIK;RGT(0.077)GQS(0.719)DDS(0.958)DIWDDT(0.246)ALIK;RGT(0.457)GQS(0.689)DDS(0.843)DIWDDT(0.011)ALIK ;; 68.565 0.0062913 83481200 15904.9 13251 14287 15001.7 14839.3 18459.2 11312 7963.1 16499.3 14459.7 TRUE FALSE FALSE 14646.01038 14396.35739 14816.48879 14939.62694 14662.35104 14630.55384 11629.38428 10391.01253 14689.36807 14962.1735 0.978869172 0.962183562 0.990263132 0.998493096 0.979961303 0.977836131 0.777252334 0.694485499 0.981766992 1 13.86903214 -4.677957031 3.017953149 0.988029207 0.705352934 0.984693972 0.012540167 0.022376715 0.390747207 0.002015501 0.009701011 2.10E-05 4.677957031 -0.282676274 SSCST(ph)PLSQANR ddPTM_HeLa_Curcumin_4h_R1 1 SSCSTPLSQANR 12 0 B1AKL4;Q9NRA8;Q9NRA8-3;Q9NRA8-2 B1AKL4 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 0 SSCS(0.133)T(0.867)PLS(0.001)QANR 204.85 1.68E-08 23467000 3057 2878.7 2738.2 3070.2 3151.5 3687.1 2492.4 860.77 3388.9 2342.7 TRUE FALSE FALSE 2815.035224 3127.522001 2839.680101 3057.496326 3113.920421 2922.353898 2562.330036 1123.214811 3017.146149 2424.108651 1.161266111 1.290174019 1.171432683 1.261286834 1.284563058 1.205537506 1.057019468 0.463351678 1.244641468 1 11.24323865 -4.266505538 3.793844463 1.134867475 0.398395398 0.818960716 0.100001903 0.099768214 2.765243219 0.017165496 0.203044282 5.41E-05 4.266505538 -0.736472077 down RGVACTQPR ddPTM_HeLa_Curcumin_4h_R1 2 RGVACTQPR 9 1 O43143 O43143 DHX15 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 0 0 ; ; 96.89 0.0037575 538610 175.96 128.963 318.64 136.37 122.98 295.28 356.08 0 144.29 248.379 FALSE FALSE TRUE 162.0325803 140.1099871 330.4490787 135.8057371 121.5135438 234.0355995 366.0706465 0 128.461748 257.0101518 0.630452063 0.545153513 1.285743292 0.52840612 0.47279667 0.910608386 1.42434314 0 0.499831416 1 8.005681536 -9.477186879 1.225078578 0.999612994 0.739405168 0 0.41788875 1.152562579 3.102382512 0.250095232 0.061738287 3.33E-10 9.477186879 -0.260207826 RGVS(ph)GDRDENSFSLNSSISSSAR ddPTM_HeLa_Curcumin_4h_R1 1 RGVSGDRDENSFSLNSSISSSAR 23 2 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 RGVS(1)GDRDENSFSLNSSISSSAR 71.527 0.0010994 14261000 924.24 909.47 830.86 1021.5 1000.3 452.38 695.39 560.78 1125.8 1087.8 TRUE FALSE FALSE 851.0854287 988.0805343 861.6524025 1017.273304 988.3720758 358.5512886 714.9007719 731.7592405 1002.302557 1125.600969 0.756116468 0.877824879 0.765504318 0.903760153 0.878083889 0.318542093 0.635128071 0.650105375 0.890459927 1 10.13647976 -3.67625406 0.113753585 1.123446849 1.09E-15 0.412696908 0.142374031 36.32952757 0.567319961 1.055419902 6.520376505 0.000210739 3.67625406 -1.123446849 RGWDS(ph)SHEDDLPVYLAR ddPTM_HeLa_Curcumin_4h_R1 1 RGWDSSHEDDLPVYLAR 17 1 Q14195-2 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 1 0 RGWDS(0.97)S(0.03)HEDDLPVYLAR 126.09 0.00018277 20783000 1884 1565 1701.5 2084 2049 2501.1 1291.3 814.23 1808.7 1825.9 TRUE FALSE FALSE 1734.879412 1700.271626 1764.559087 2075.37696 2024.567013 1982.343667 1327.530403 1062.484979 1610.290135 1889.349889 0.918241466 0.899924168 0.933950401 1.09846089 1.071568069 1.049219987 0.702638728 0.5623548 0.852298531 1 10.88367418 -4.619859357 4.225417041 0.976336856 0.590956242 0.772032508 0.07654547 0.067429064 2.117408354 0.010549206 0.045127196 2.40E-05 4.619859357 -0.385380614 RHERIHT(ph)GERPY(ph)K ddPTM_HeLa_Curcumin_4h_R1 2 RHERIHTGERPYK 13 3 Q8N8Z8-2;Q8N8Z8 Q8N8Z8-2 ZNF441 Zinc finger protein 441 2 0 RHERIHT(1)GERPY(1)K;RHERIHT(1)GERPY(1)K ; 85.522 0.0076942 51664000 4781 6364.9 4509.8 6940 4857.4 6282.9 3523.3 1890.02 8272.1 6237 TRUE FALSE FALSE 4402.578805 6915.053595 4676.937155 6911.284119 4799.478677 4979.755717 3622.154316 2466.278397 7364.671326 6453.735286 0.6821753 1.071480823 0.724686859 1.070896746 0.743674549 0.771608301 0.561249285 0.382147437 1.141148653 1 12.65591869 -4.563092106 1.29492121 0.866598758 0.298509334 0.562940046 0.155939994 0.493233274 1.021760951 0.021892824 0.318759852 2.73E-05 4.563092106 -0.568089424 RHGAPAAPS(ph)PPPR ddPTM_HeLa_Curcumin_4h_R1 1 RHGAPAAPSPPPR 13 1 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 0 RHGAPAAPS(1)PPPR 79.317 0.010668 2875500 246.49 263.07 586.51 334.58 207.11 403.15 309.69 132.36 454.37 450.9 TRUE FALSE FALSE 226.9800564 285.8085986 608.2465765 333.1955966 204.6403485 319.5321456 318.3790679 172.7159547 404.5267478 466.5687414 0.48648792 0.61257554 1.303659081 0.714140419 0.43860707 0.68485545 0.682384051 0.370183296 0.867024967 1 8.865945845 -5.985773433 22.37096241 0.785562169 0.565504478 0.264830727 0.228598505 112.1223747 176305.1073 0.039962965 0.072398515 1.03E-06 5.985773433 -0.220057691 RHS(ph)IEKETPTNVR ddPTM_HeLa_Curcumin_4h_R1 1 RHSIEKETPTNVR 13 2 J3KNG6;Q08AE8-4;Q08AE8-3;Q08AE8-5;Q08AE8-2;Q08AE8 J3KNG6 SPIRE1 Protein spire homolog 1 1 0 RHS(0.999)IEKET(0.001)PT(0.001)NVR 48.115 0.020347 10441000 2539 2338.9 1674.3 2304.8 1846.6 2311.4 1953.7 1725.9 3287.9 3025.5 TRUE FALSE FALSE 2338.035471 2541.064094 1736.351031 2295.263348 1824.580501 1831.989585 2008.515564 2252.118965 2927.225596 3130.6359 0.746824462 0.811676661 0.554632058 0.733162023 0.582814661 0.5851813 0.64156792 0.719380674 0.935025883 1 11.61224001 -8.559825992 0.385605944 1.053465967 0.621017946 0.750385477 0.071221271 0.505184087 0.147946303 0.090853805 0.029583024 2.76E-09 8.559825992 -0.432448021 RHS(ph)PPIEK ddPTM_HeLa_Curcumin_4h_R1 1 RHSPPIEK 8 1 F5GZK9;Q8IZD4-2;Q8IZD4 F5GZK9 DCP1B mRNA-decapping enzyme 1B 1 0 RHS(1)PPIEK 80.834 0.014568 31328000 8335.9 9416.1 7537.8 7160.4 7173.6 9359.2 6528.3 2591.4 7783 8295.3 TRUE FALSE FALSE 7676.104719 10229.98573 7817.157499 7130.772162 7088.059505 7417.99642 6711.466528 3381.505931 6929.224372 8583.561058 0.894279736 1.191811377 0.910712634 0.830747532 0.825771432 0.864209664 0.781897686 0.393951404 0.807266859 1 13.06736059 -4.034811976 0.875511846 0.955516415 1.76E-37 0.674471212 0.108342518 1.27073124 0.553635281 0.015866581 1.274566496 9.23E-05 4.034811976 -0.955516415 MCDFGISGYLVDS(ph)VAK ddPTM_HeLa_Curcumin_4h_R1 1 MCDFGISGYLVDSVAK 16 0 P52564-2;P46734-2;P52564;P46734;P46734-3 P52564-2 MAP2K6;MAP2K3 Dual specificity mitogen-activated protein kinase kinase 6;Dual specificity mitogen-activated protein kinase kinase 3 1 0 MCDFGISGYLVDS(1)VAK 112.67 0.001426 6571000 433.02 564.15 432.03 299.8 455.79 956.29 1030.1 2990.6 356.36 832.13 TRUE FALSE FALSE 398.7460101 612.9126122 448.0414119 298.559507 450.3550019 757.9446744 1059.001834 3902.420173 317.2681996 861.0464556 0.463094654 0.711822932 0.520345225 0.346740301 0.523032177 0.880259909 1.229900927 4.532183075 0.368468156 1 9.749947266 -4.219903393 2.586460144 0.685856457 5.583642672 0.967292933 0.215241587 0.084597181 0.654716633 0.035751047 0.93686757 6.03E-05 4.219903393 4.897786215 up RHS(ph)VVAGGGGGEGR ddPTM_HeLa_Curcumin_4h_R1 2 RHSVVAGGGGGEGR 14 1 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 1 0 RHS(1)VVAGGGGGEGR;RHS(1)VVAGGGGGEGR ; 77.027 0.010589 5617200 161.65 0 195.6 118.92 67.617 419.8 313.39 586.03 305.25 0 TRUE FALSE FALSE 148.8552319 0 202.8491081 118.4279405 66.81071144 332.7287479 322.18288 764.7078492 271.7648387 0 0 RIDFIPVS(ph)PAPS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 2 RIDFIPVSPAPSPTR 15 1 Q96E09 Q96E09 FAM122A Protein FAM122A 2 0 RIDFIPVS(0.967)PAPS(0.703)PT(0.329)R;RIDFIPVS(0.979)PAPS(0.619)PT(0.402)R ; 82.362 0.005691 53336000 5812.1 4823 4871.4 5828.4 5421.6 6110.5 5089.9 3498.6 6090.5 4980.1 TRUE FALSE FALSE 5352.066152 5239.878629 5051.938369 5804.283625 5356.950961 4843.11342 5232.708895 4565.307034 5422.387388 5153.158104 1.038599252 1.016828617 0.980357728 1.126354656 1.039547177 0.939834044 1.015437289 0.885924115 1.052245493 1 12.33124114 -3.171647645 1.0020585 1.022611086 2.50E-18 0.455281936 0.045726132 9.956625761 1.439743248 0.006719877 18.21239183 0.000673523 3.171647645 -1.022611086 RIDFIPVS(ph)PAPSPTR ddPTM_HeLa_Curcumin_4h_R1 1 RIDFIPVSPAPSPTR 15 1 Q96E09 Q96E09 FAM122A Protein FAM122A 1 0 RIDFIPVS(0.996)PAPS(0.004)PTR 93.029 0.0029766 15880000 1592 1240.6 1277.5 1373 1460.8 1487.4 1618 2024.2 1717.6 1694.1 TRUE FALSE FALSE 1465.99152 1347.831936 1324.845274 1367.31889 1443.380914 1178.896474 1663.396725 2641.369262 1529.183577 1752.969849 0.836290208 0.768884837 0.755771855 0.780001373 0.823391751 0.672513834 0.948902074 1.506796745 0.872338779 1 10.77558547 -4.275715356 4.127057824 0.866020843 1.552090045 0.822466844 0.093772716 0.084133621 3.104110789 0.016690757 0.16651842 5.30E-05 4.275715356 0.686069202 RIDFT(ph)PVSPAPSPT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 RIDFTPVSPAPSPTR 15 1 Q7Z309;Q7Z309-2;G1UD79;Q7Z309-5;Q7Z309-4;Q7Z309-3 Q7Z309 FAM122B;SPACIA2 Protein FAM122B 2 0 RIDFT(0.566)PVS(0.434)PAPS(0.475)PT(0.525)R 89.913 0.0043362 12191000 1633.1 1493.4 1251.2 1436.9 1385.9 1761 1546.3 1223.7 1419.5 1511.7 TRUE FALSE FALSE 1503.838412 1622.482842 1297.570573 1430.954489 1369.374048 1395.748749 1589.685016 1596.800497 1263.784401 1564.231462 0.961391231 1.037239616 0.829525939 0.914797153 0.875429296 0.892290421 1.016272243 1.020821109 0.807926724 1 10.61123829 -6.792794908 24.99993742 0.985419008 0.924826985 0 0.080769811 249.8433305 199200.5346 0.009799571 0.012879867 1.61E-07 6.792794908 -0.060592023 RIDFTPVS(ph)PAPS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 RIDFTPVSPAPSPTR 15 1 Q7Z309;Q7Z309-2;G1UD79;Q7Z309-5;Q7Z309-4;Q7Z309-3 Q7Z309 FAM122B;SPACIA2 Protein FAM122B 2 0 RIDFT(0.003)PVS(0.997)PAPS(0.586)PT(0.414)R 61.087 0.018192 83040000 2592.5 2491.4 2606.2 2544.7 2486 2773.7 2431 1921.6 2928.9 2673.6 TRUE FALSE FALSE 2387.300889 2706.745515 2702.788065 2534.170706 2456.356074 2198.403354 2499.207317 2507.486994 2607.606998 2766.507401 0.862929515 0.978398075 0.976967589 0.916018047 0.887890657 0.794649367 0.90337995 0.906372776 0.942562813 1 11.43385007 -5.801702318 3.24363142 0.940443349 0.86821583 0.388828121 0.04555023 0.278470429 6.016829991 0.00897677 0.017775167 1.58E-06 5.801702318 -0.072227518 RIDFTPVS(ph)PAPSPT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 RIDFTPVSPAPSPTR 15 1 Q7Z309;Q7Z309-2;G1UD79;Q7Z309-5;Q7Z309-4;Q7Z309-3 Q7Z309 FAM122B;SPACIA2 Protein FAM122B 2 0 RIDFTPVS(0.603)PAPS(0.46)PT(0.936)R 113.78 0.0013705 38985000 3473.1 2747.1 2989.1 3050.3 3472.5 3476.7 3056.5 2461 3218.7 2534.8 TRUE FALSE FALSE 3198.20047 2984.547083 3099.878675 3037.678667 3431.092705 2755.59323 3142.257164 3211.347571 2865.616663 2622.884111 1.21934494 1.137887515 1.181858803 1.158144446 1.308137363 1.050596638 1.198016012 1.2243574 1.092544139 1 11.35693835 -9.346691299 0.852005935 0.98851692 1.185324384 0.36861788 0.06838068 0.404804491 0.475722086 0.054264823 0.011318914 4.50E-10 9.346691299 0.196807464 RIDFTPVSPAPS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 RIDFTPVSPAPSPTR 15 1 Q7Z309;Q7Z309-2;G1UD79;Q7Z309-5;Q7Z309-4;Q7Z309-3 Q7Z309 FAM122B;SPACIA2 Protein FAM122B 1 0 RIDFTPVS(0.001)PAPS(0.5)PT(0.5)R 102.24 0.0014964 7640500 1909 1637.3 1823.4 1818 1908.6 2188.3 1612.6 1789.2 2061.5 1868.6 TRUE FALSE FALSE 1757.900636 1778.820916 1890.976808 1810.477598 1885.841192 1734.421913 1657.845216 2334.718844 1835.358608 1933.533711 0.90916472 0.919984434 0.97799009 0.936356882 0.975334012 0.897021812 0.85741728 1.207488047 0.949225037 1 10.9170242 -4.249170054 24.99572027 0.946066096 1.207488207 0.792004985 0.041466603 788.6474128 1606646.422 0.006682733 0.153061781 5.63E-05 4.249170054 0.261422111 RIDFTPVSPAPSPT(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 RIDFTPVSPAPSPTR 15 1 Q7Z309;Q7Z309-2;G1UD79;Q7Z309-5;Q7Z309-4;Q7Z309-3 Q7Z309 FAM122B;SPACIA2 Protein FAM122B 1 0 RIDFTPVSPAPS(0.118)PT(0.882)R;RIDFTPVSPAPS(0.01)PT(0.99)R ; 186.96 0.00013229 31805000 1605.7 1272.18 1413.34 1623.77 1488.22 1820.38 1173.31 716.06 1990.18 1519.74 TRUE FALSE FALSE 1478.607151 1382.14157 1465.719624 1617.05127 1470.473948 1442.812668 1206.229921 934.3833977 1771.862233 1572.550852 0.940260309 0.878916932 0.932065009 1.028298238 0.935088329 0.917498259 0.767053046 0.594183264 1.126743998 1 10.61889096 -4.444025505 1.472665669 0.963796768 0.516467976 0.78396858 0.0644471 0.195987196 0.494249454 0.006408007 0.115155326 3.60E-05 4.444025505 -0.447328791 RIDIS(ph)PSTFR ddPTM_HeLa_Curcumin_4h_R1 1 RIDISPSTFR 10 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 RIDIS(0.961)PS(0.02)T(0.02)FR 71.976 0.019568 138680000 2621.8 2035.8 2346.4 2106.2 2343.3 2827.6 2044.6 2220.1 2540.4 2627 TRUE FALSE FALSE 2414.281763 2211.765481 2433.359648 2097.485102 2315.357678 2241.123886 2101.965973 2896.99827 2261.724476 2718.288054 0.888162592 0.813661185 0.895180937 0.77161988 0.851770538 0.824461515 0.773268296 1.065743664 0.832040031 1 11.40848263 -8.517057732 0.702437034 0.995243728 0.849649394 0 0.094182059 0.537978993 0.547095232 0.038418393 0.017363963 3.04E-09 8.517057732 -0.145594334 RIDISPSTLR ddPTM_HeLa_Curcumin_4h_R1 1 RIDISPSTLR 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 0 128.88 0.00070016 0 1981.9 1806.6 1899 2070.8 1750.6 2283 2007.1 1831.1 1874 1813.4 FALSE FALSE TRUE 1825.030524 1962.754454 1969.378611 2062.231578 1729.725238 1809.480065 2063.413824 2389.393961 1668.426889 1876.415515 0.972615345 1.046012697 1.049542916 1.099027141 0.921824204 0.964328024 1.099657196 1.273382117 0.889156413 1 10.87376362 -4.385462586 2.68564146 0.997823166 1.292723376 0.677566234 0.059422151 0.134824395 1.481120474 0.007076221 0.076641303 4.12E-05 4.385462586 0.294900211 RIDT(ph)PSLEEPSDLEELEQFAK ddPTM_HeLa_Curcumin_4h_R1 2 RIDTPSLEEPSDLEELEQFAK 21 1 P14859-6;P14859-2;P14859;P14859-3;P14859-5;P14859-4;A0A0C4DG88 P14859-6 POU2F1 "POU domain, class 2, transcription factor 1;POU domain protein" 1 0 RIDT(0.662)PS(0.241)LEEPS(0.097)DLEELEQFAK;RIDT(0.861)PS(0.138)LEEPSDLEELEQFAK ; 87.958 0.00033561 13690300 7206.1 4837.7 5679.3 6116.2 5804.6 7820.2 5095.2 2322.55 6824.8 5077 TRUE FALSE FALSE 6635.729581 5255.849232 5889.779854 6090.892785 5735.383936 6198.202368 5238.157599 3030.684803 6076.136515 5253.425372 1.263124364 1.000461386 1.121131345 1.159413593 1.091741774 1.179840186 0.997093749 0.576896898 1.156604707 1 12.35904269 -4.287652195 2.814306275 1.120674468 0.494661245 0.822951537 0.075713538 0.154193869 1.735318875 0.014028733 0.214271223 5.16E-05 4.287652195 -0.626013222 RIDTPSLEEPS(ph)DLEELEQFAK ddPTM_HeLa_Curcumin_4h_R1 1 RIDTPSLEEPSDLEELEQFAK 21 1 P14859-6;P14859-2;P14859;P14859-3;P14859-5;P14859-4;A0A0C4DG88 P14859-6 POU2F1 "POU domain, class 2, transcription factor 1;POU domain protein" 1 0 RIDT(0.183)PS(0.05)LEEPS(0.767)DLEELEQFAK 109.77 1.96E-05 10661000 3302.1 2453.9 2623 2826.8 2816.3 3106 2689.4 1426.7 3290.6 2484.9 TRUE FALSE FALSE 3040.735301 2666.004182 2720.210687 2815.103451 2782.717462 2461.780588 2764.857326 1861.694262 2929.629413 2571.25009 1.182590255 1.036851371 1.057933142 1.094838445 1.08224302 0.957425572 1.075296929 0.724042468 1.139379411 1 11.32825422 -3.780095139 1.485045385 1.078194031 3.48E-23 0.723681561 0.063206332 2.035597109 1.524746755 0.011028226 4.606723424 0.000165922 3.780095139 -1.078194031 RIEQHYFEDR ddPTM_HeLa_Curcumin_4h_R1 1 RIEQHYFEDR 10 1 C9JNK6;O75431-2;O75431 C9JNK6 MTX2 Metaxin-2 0 0 112.94 0.0018381 15102000 2565.5 1744.6 2126 1975.7 2175.6 2158.1 1284.7 1303.8 2559.1 1986.7 FALSE FALSE TRUE 2362.437968 1895.39545 2204.79143 1967.525077 2149.657391 1710.485733 1320.745224 1701.322618 2278.373133 2055.737677 1.149192328 0.922002584 1.072506213 0.957089564 1.045686624 0.832054475 0.642467781 0.827597138 1.108299545 1 11.00544047 -5.157441196 3.036588174 1.051522709 0.73325278 0.722033105 0.077374762 0.10144862 1.784915757 0.011908876 0.034525367 6.96E-06 5.157441196 -0.318269929 RIES(ph)PLK ddPTM_HeLa_Curcumin_4h_R1 1 RIESPLK 7 1 E9PPG9;E9PQ57;P78406 E9PPG9 RAE1 mRNA export factor 1 0 RIES(1)PLK 82.287 0.014928 5182100 3948.7 3323.6 3565.7 3442.2 4947.3 5317.4 3685.4 2679.9 3971 3738.7 TRUE FALSE FALSE 3636.156228 3610.877174 3697.847979 3427.957088 4888.306679 4214.511301 3788.802405 3496.989173 3535.391235 3868.619547 0.939910525 0.933376139 0.955857234 0.8860931 1.263579067 1.089409607 0.979368056 0.903937214 0.913863768 1 11.91760314 RIESLIDRDYMER ddPTM_HeLa_Curcumin_4h_R1 2 RIESLIDRDYMER 13 2 A0A669KAX4;K4DI93;Q13620-1;Q13620;Q13620-3;A0A0A0MR50;Q13619-2;Q13619 A0A669KAX4 CUL4B;CUL4A Cullin-4B;Cullin-4A 0 0 ; ; 96.334 0.0034381 50944000 2507 1788.42 2159.74 2573.2 1881.24 2628.33 2315.1 1954.6 2696.5 2667.3 FALSE FALSE TRUE 2308.568305 1943.003056 2239.781864 2562.55278 1858.807442 2083.184731 2380.055475 2550.548542 2400.700696 2759.988476 0.836441284 0.703989554 0.811518556 0.928465029 0.673483769 0.754780228 0.862342541 0.924115649 0.869822725 1 11.43044653 -8.766368672 0.775332663 0.99550725 0.807634681 0.184684433 0.088507386 0.447208274 0.523551846 0.045511558 0.017492745 1.71E-09 8.766368672 -0.18787257 RIEYIEAR ddPTM_HeLa_Curcumin_4h_R1 2 RIEYIEAR 8 1 Q8WUW1;Q8WUW1-2 Q8WUW1 BRK1 Protein BRICK1 0 0 ; ; 136.99 0.0023951 2816100 4088.5 2095.7 3031.9 2970.2 3352.6 3748.9 2940.1 3150.1 3414.9 3289.9 FALSE FALSE TRUE 3764.890911 2276.84297 3144.264881 2957.910099 3312.622435 2971.335881 3022.591293 4110.550989 3040.294014 3404.22378 1.105946951 0.668828819 0.923636366 0.868894142 0.973091855 0.872838002 0.887894418 1.20748554 0.893094641 1 11.73311016 RILS(ph)DVTHSAVFGVPASK ddPTM_HeLa_Curcumin_4h_R1 2 RILSDVTHSAVFGVPASK 18 1 Q2M2I8-2;Q2M2I8;E9PG46 Q2M2I8-2 AAK1 AP2-associated protein kinase 1 1 0 RILS(0.875)DVT(0.124)HS(0.001)AVFGVPASK;RILS(0.726)DVT(0.274)HSAVFGVPASK ; 96.128 0.00092259 124376000 12484.2 9106 10090.9 11908.9 8901.7 10394.8 7661.2 6744.7 12573.5 10822.2 TRUE FALSE FALSE 11496.0624 9893.082064 10464.87763 11859.62413 8795.553041 8238.801306 7876.152653 8801.127981 11194.21851 11198.27064 1.026592655 0.883447309 0.934508369 1.059058537 0.785438513 0.73572086 0.703336515 0.785936352 0.999638146 1 13.45098833 -5.672247896 5.300902641 0.998333472 0.742124202 0.831778701 0.050860282 0.059205565 2.722794307 0.007844266 0.015842563 2.13E-06 5.672247896 -0.256209271 RIPLAEWESR ddPTM_HeLa_Curcumin_4h_R1 2 RIPLAEWESR 10 1 P31930 P31930 UQCRC1 "Cytochrome b-c1 complex subunit 1, mitochondrial" 0 0 ; ; 117.14 0.0025943 12151000 2457.6 3010.6 2613.1 2818 2682.1 4267.9 3350.1 2453.6 2718.2 2551.4 FALSE FALSE TRUE 2263.078367 3270.822849 2709.943785 2806.339863 2650.117709 3382.689431 3444.09479 3201.691345 2420.020261 2640.06096 0.85720686 1.238919441 1.026470156 1.062982978 1.003809287 1.281292168 1.304551236 1.21273387 0.916653175 1 11.36635553 -5.531399098 0.563006485 0.943118963 1.327863779 0.51031234 0.104826472 0.776701846 0.359668383 0.025095691 0.152494297 2.94E-06 5.531399098 0.384744816 VSVGAPDLS(ph)LEASEGSIK ddPTM_HeLa_Curcumin_4h_R1 1 VSVGAPDLSLEASEGSIK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VSVGAPDLS(0.974)LEAS(0.013)EGS(0.013)IK 92.096 0.00246 5261900 1582 1304.6 1357.8 1484.4 1730.5 1703.9 1763.4 2971.9 1427.4 1085 TRUE FALSE FALSE 1456.783031 1417.363811 1408.121262 1478.257946 1709.864918 1350.491933 1812.876258 3878.018629 1270.817791 1122.703669 1.297566821 1.262455846 1.254223444 1.316694678 1.522988625 1.202892598 1.614741546 3.45417828 1.131926283 1 10.13276147 -4.219662702 2.357744103 1.201998471 4.145912673 0.959644737 0.134718702 0.110944764 0.664835961 0.024220744 0.693555651 6.03E-05 4.219662702 2.943914202 up RIPSIVSS(ph)PLNSPLDR ddPTM_HeLa_Curcumin_4h_R1 2 RIPSIVSSPLNSPLDR 16 1 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 0 RIPS(0.001)IVS(0.342)S(0.656)PLNS(0.001)PLDR;RIPSIVS(0.406)S(0.593)PLNS(0.001)PLDR ; 101.05 0.001235 108633000 3516 2954.71 2833.12 3169.1 2921.05 4350.9 3733.54 4253.9 4299.2 4044.4 TRUE FALSE FALSE 3237.70489 3210.101966 2938.117919 3155.987104 2886.218387 3448.474295 3838.293084 5550.894527 3827.588516 4184.942599 0.773655746 0.767059975 0.70206887 0.754129126 0.689667377 0.824019497 0.917167439 1.326396813 0.914609562 1 12.03099212 -2.851965161 12.66121144 0.867522547 1.182279277 0 0.180404916 0 0 0.024710127 0 0.00140616 2.851965161 0.31475673 RIQT(ph)LIY(ph)DALERPR ddPTM_HeLa_Curcumin_4h_R1 2 RIQTLIYDALERPR 14 2 A0A1W2PRN8;E7ET42;O43525 A0A1W2PRN8 KCNQ3 Potassium voltage-gated channel subfamily KQT member 3 2 0 RIQT(1)LIY(1)DALERPR;RIQT(1)LIY(1)DALERPR ; 74.537 0.0093156 93056000 5017.9 4282.1 3823.6 5189.7 6037.8 459.15 1752.25 2076.66 5877.6 3887.6 TRUE FALSE FALSE 4620.72792 4652.225643 3965.30598 5168.226396 5965.803178 363.9171143 1801.413419 2709.824074 5232.841985 4022.693811 1.148665083 1.156495091 0.98573398 1.284767531 1.483036855 0.090466024 0.447812711 0.673634187 1.300830297 1 11.97394622 -5.258819322 24.99893903 1.112174394 0.408355146 0.756122818 0.201932716 88.99258869 849104.6441 0.027721628 0.067273998 5.51E-06 5.258819322 -0.703819248 RIQTSLTSASLGSADENSVAQADDSLK ddPTM_HeLa_Curcumin_4h_R1 1 RIQTSLTSASLGSADENSVAQADDSLK 27 1 H3BMQ0;A0A2R8YDR3;A0A2R8Y7X5;P49815-3;P49815-5;A0A2R8Y6C9;A0A2R8Y5F1 H3BMQ0 TSC2 Tuberin 0 0 51.857 0.018913 47732000 3542.4 2407.1 2908.1 3073.5 2802.5 3755.8 2773.5 2912.1 2906.4 3109.7 FALSE FALSE TRUE 3262.015302 2615.158998 3015.876744 3060.782671 2769.082018 2976.804743 2851.316946 3799.985884 2587.575191 3217.761844 1.013752869 0.812726089 0.937259154 0.951214795 0.860561518 0.925116552 0.88611808 1.180940688 0.804153731 1 11.65184184 SNS(ph)DESNFSEK ddPTM_HeLa_Curcumin_4h_R1 4 SNSDESNFSEK 11 0 A0A087WWW9;O95999 A0A087WWW9 BCL10 B-cell lymphoma/leukemia 10 1 0 S(0.254)NS(0.724)DES(0.022)NFSEK;S(0.129)NS(0.713)DES(0.018)NFS(0.139)EK;S(0.207)NS(0.791)DES(0.001)NFSEK;S(0.016)NS(0.979)DES(0.005)NFSEK ;;; 201.76 3.56E-07 217319000 7813 6677.8 6823.8 6935.5 7853.9 11691.3 13720.9 39853.3 7957.7 7406.32 TRUE FALSE FALSE 7194.592806 7254.999276 7076.696031 6906.802739 7760.247372 9266.392592 14105.87153 52004.38771 7084.760219 7663.689069 0.938789758 0.946671924 0.923405943 0.901237338 1.012599455 1.209129508 1.840611147 6.785816497 0.924458202 1 12.90382331 -4.218614753 2.532855031 0.975712296 8.43018475 0.997136573 0.092763361 0.024560167 0.178715768 0.015150577 0.408701146 6.04E-05 4.218614753 7.454472455 up RIS(ph)FSASHR ddPTM_HeLa_Curcumin_4h_R1 1 RISFSASHR 9 1 E9PKY8;E9PJM0;Q03393 E9PKY8 PTS 6-pyruvoyl tetrahydrobiopterin synthase 1 0 RIS(0.96)FS(0.039)AS(0.001)HR 92.943 0.008093 11709000 1003.1 766.04 1083.5 978.6 1183.8 1379.6 1085.9 768.93 874.12 932.17 TRUE FALSE FALSE 923.7035765 832.2530842 1123.655463 974.5508125 1169.683958 1093.455409 1116.367431 1003.373217 778.2312229 964.5628381 0.957639606 0.862829306 1.164937543 1.010354923 1.212657084 1.133627966 1.157381756 1.040236237 0.806822731 1 9.913731418 -6.745607392 24.99999858 0.970650013 1.121436752 0.569258372 0.083715147 130.4552748 205999.0734 0.009982291 0.014089993 1.80E-07 6.745607392 0.150786739 RIS(ph)GLIYEETR ddPTM_HeLa_Curcumin_4h_R1 3 RISGLIYEETR 11 1 P62805 P62805 HIST1H4A Histone H4 1 0 RIS(1)GLIYEETR;RIS(1)GLIYEETR;RIS(1)GLIYEETR ;; 145.61 0.0015159 56100000 6757.2 4008.2 5623.8 6369.8 6071.7 8554.2 7074.7 5147.2 6327.6 5540.5 TRUE FALSE FALSE 6222.36049 4354.650948 5832.222975 6343.443455 5999.298943 6779.962494 7273.197041 6716.557585 5633.478111 5733.031963 1.085352485 0.759572069 1.017301667 1.106472718 1.046444357 1.182613762 1.268647565 1.171554184 0.982635043 1 12.48508261 -5.314101764 1.644549688 1.018562325 1.227437628 0.511790958 0.092595901 0.280246227 1.434602852 0.014500885 0.048596868 4.85E-06 5.314101764 0.208875303 RIS(ph)QSQPVR ddPTM_HeLa_Curcumin_4h_R1 1 RISQSQPVR 9 1 E7EMW7;O95071-2;O95071 E7EMW7 UBR5 E3 ubiquitin-protein ligase UBR5 1 0 RIS(0.5)QS(0.5)QPVR 102.05 0.018791 36472000 3490.5 3214.8 3188.7 3765.3 3641.5 3842.7 4718.2 4394.1 4079.7 3732.4 TRUE FALSE FALSE 3214.223242 3492.672987 3306.876027 3749.720186 3598.077491 3045.680704 4850.579994 5733.840862 3632.167117 3862.100622 0.83224741 0.904345414 0.856237667 0.970901733 0.931637428 0.78860729 1.255943454 1.484643054 0.940464134 1 11.91517004 -4.582594049 4.039787617 0.911147609 1.445004877 0.899035654 0.064493905 0.050669238 1.628297464 0.010814978 0.0493973 2.61E-05 4.582594049 0.533857268 SHS(ph)VPENMVEPPLSGR ddPTM_HeLa_Curcumin_4h_R1 1 SHSVPENMVEPPLSGR 16 0 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 0 S(0.095)HS(0.905)VPENMVEPPLSGR 71.001 0.014415 16948000 1534.4 875.35 1114 1291.6 1108 1708.2 1860.1 3395.8 1216.4 1180.5 TRUE FALSE FALSE 1412.950621 951.0113535 1155.28582 1286.255701 1094.787824 1353.900065 1912.2894 4431.163788 1082.963963 1221.522287 1.156712928 0.778546052 0.945775474 1.052994051 0.896248751 1.108371152 1.565496938 3.627575063 0.88656914 1 10.25446447 -4.218353392 2.208147738 1.031411884 4.490018789 0.979099241 0.115906371 0.07514121 0.376414607 0.017225011 0.527838419 6.05E-05 4.218353392 3.458606905 up SPFSVAVS(ph)PSLDLSK ddPTM_HeLa_Curcumin_4h_R1 1 SPFSVAVSPSLDLSK 15 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 SPFSVAVS(0.895)PS(0.105)LDLSK 200.69 9.45E-09 41618000 3295.3 2867.3 2652.8 2901.6 2982.5 4332 3647.5 7004.6 3499.2 2903.4 TRUE FALSE FALSE 3034.473528 3115.136636 2751.115102 2889.593948 2946.935635 3433.494368 3749.839033 9140.270295 3115.346515 3004.292934 1.010045823 1.036895104 0.915727981 0.961821637 0.98090822 1.142862711 1.248160255 3.042403153 1.036964964 1 11.55280977 -4.218216038 2.704224527 1.003902687 3.573943892 0.99056713 0.059083327 0.035984178 0.314333427 0.008476912 0.215785498 6.05E-05 4.218216038 2.570041205 up LEPVYS(ph)PPGS(ph)PPPGDPR ddPTM_HeLa_Curcumin_4h_R1 1 LEPVYSPPGSPPPGDPR 17 0 A0A0A6YYC0;E9PJN1;O75676-2;O75676 A0A0A6YYC0 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 2 0 LEPVY(0.028)S(0.972)PPGS(1)PPPGDPR 102.84 0.0039283 14898000 1054 1159 1163.9 1337.3 1398 1827.2 2272.9 6836.3 1524.6 1161.9 TRUE FALSE FALSE 970.5747878 1259.178796 1207.035158 1331.766607 1381.329763 1448.218123 2336.671457 8920.6564 1357.355194 1202.275939 0.807281221 1.047329282 1.003958508 1.107704616 1.148929059 1.204563842 1.943540066 7.419807811 1.128988072 1 10.23155234 -4.218006732 2.516751964 0.970140261 9.26677469 0.994821547 0.136789203 0.034434084 0.245797757 0.023313187 0.635385594 6.05E-05 4.218006732 8.296634429 up RKADTTTPTPTAILAPGS(ph)PAS(ph)PPGSLEPK ddPTM_HeLa_Curcumin_4h_R1 2 RKADTTTPTPTAILAPGSPASPPGSLEPK 29 2 P25440-2;P25440;A0A0G2JK44;A0A140T9E9;H0Y6K2;P25440-3;P25440-4;A0A0G2JHL0;A0A140T9V2;A0A140T9F7;U3KQA6;E9PIQ3;H0YDJ7;U3KPW0 P25440-2 BRD2 Bromodomain-containing protein 2 2 0 RKADT(0.002)T(0.001)T(0.001)PT(0.002)PT(0.005)AILAPGS(0.942)PAS(0.958)PPGS(0.09)LEPK;RKADT(0.116)T(0.027)T(0.027)PT(0.023)PT(0.487)AILAPGS(0.63)PAS(0.617)PPGS(0.074)LEPK ; 64.315 0.00065885 47547000 1871.92 1458.34 1500.85 1819.33 1514.69 1627.69 1717.7 1284.56 1990.68 1784.19 TRUE FALSE FALSE 1723.755557 1584.392411 1556.472821 1811.802095 1496.628311 1290.088746 1765.894039 1676.216431 1772.307384 1846.19047 0.933682404 0.858195531 0.84307272 0.981373333 0.810657587 0.698784209 0.956506963 0.907932555 0.959980789 1 10.85033569 -7.759053832 0.670368226 0.991975658 0.857433063 0.263802886 0.075690642 0.538341449 0.542392656 0.026595488 0.022009522 1.74E-08 7.759053832 -0.134542596 RKADTTTPTPTAILAPGS(ph)PASPPGSLEPK ddPTM_HeLa_Curcumin_4h_R1 2 RKADTTTPTPTAILAPGSPASPPGSLEPK 29 2 P25440-2;P25440;A0A0G2JK44;A0A140T9E9;H0Y6K2;P25440-3;P25440-4;A0A0G2JHL0;A0A140T9V2;A0A140T9F7;U3KQA6;E9PIQ3;H0YDJ7;U3KPW0 P25440-2 BRD2 Bromodomain-containing protein 2 1 0 RKADTTTPTPTAILAPGS(0.836)PAS(0.155)PPGS(0.009)LEPK;RKADTTTPTPTAILAPGS(0.656)PAS(0.328)PPGS(0.015)LEPK ; 74.63 2.97E-05 56029000 2705.8 2332.7 2427.2 2662.7 2551.44 3090.3 1947.11 1766.68 3278.4 2799.3 TRUE FALSE FALSE 2491.633075 2534.328194 2517.154167 2651.682453 2521.015744 2449.336945 2001.740666 2305.332599 2918.767722 2896.575467 0.860199606 0.874939467 0.869010387 0.915454295 0.87034354 0.84559749 0.69107147 0.795882112 1.007661549 1 11.50013254 -5.813880812 0.033132554 1.673084631 9.19E-11 0.719269716 0.046206089 112.2354218 1.128608902 25.17249732 31.88086646 1.54E-06 5.813880812 -1.673084631 RKAEDS(ph)DS(ph)EPEPEDNVR ddPTM_HeLa_Curcumin_4h_R1 1 RKAEDSDSEPEPEDNVR 17 2 Q9H0D6-2;Q9H0D6 Q9H0D6-2 XRN2 5-3 exoribonuclease 2 2 0 RKAEDS(1)DS(1)EPEPEDNVR 82.034 0.0061714 88407000 7980.7 6360.8 6588.6 7470.6 7332.2 8106.1 6480.9 6355 8113.5 6849.3 TRUE FALSE FALSE 7349.019174 6910.599209 6832.779312 7439.688637 7244.768304 6424.803485 6662.736612 8292.610245 7223.469349 7087.312665 1.036926057 0.975066225 0.964086056 1.049719264 1.02221655 0.906521807 0.940093506 1.170064118 1.019211327 1 12.79102298 -7.269476646 24.2153751 1.017437302 0.998689991 0.0054464 0.068481847 1798.328297 5418167.354 0.011282909 0.01302272 5.38E-08 7.269476646 -0.018747312 RKAS(ph)PEPEGEAAGK ddPTM_HeLa_Curcumin_4h_R1 2 RKASPEPEGEAAGK 14 2 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 0 RKAS(1)PEPEGEAAGK;RKAS(1)PEPEGEAAGK ; 94.569 0.0055472 12662000 8871.6 7721.2 7844.3 7645 8688.1 9646.6 7483.4 4770.9 9041.4 8497.2 TRUE FALSE FALSE 8169.403499 8388.586123 8135.016659 7613.367016 8584.500082 7645.78642 7693.364063 6225.525447 8049.58104 8792.477068 0.929135605 0.954064032 0.925224666 0.865895578 0.97634603 0.869582754 0.87499393 0.708051372 0.915507766 1 13.10205395 -2.797433444 0.45047923 0.965849248 1.00E-41 0.706156307 0.041988779 5.714058114 0.286644831 0.009068078 3.960782092 0.001594287 2.797433444 -0.965849248 RKAS(ph)PEPPDSAEGALK ddPTM_HeLa_Curcumin_4h_R1 1 RKASPEPPDSAEGALK 16 2 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 0 RKAS(0.991)PEPPDS(0.009)AEGALK 49.655 0.017643 36499000 7731.8 5373 5747.2 5752.7 5950 6911.2 6105.4 4586.1 6360.7 6127.2 TRUE FALSE FALSE 7119.819871 5837.418178 5960.196288 5728.896852 5879.050136 5477.739215 6276.701092 5984.380778 5662.947124 6340.119744 1.12297877 0.92071103 0.940076296 0.903594425 0.927277461 0.863980404 0.989997247 0.943890813 0.893192456 1 12.63029437 -7.244318818 24.50002232 1.058073307 0.926673408 0.094232915 0.066148227 329.2306199 471138.6996 0.008848165 0.010820986 5.70E-08 7.244318818 -0.131399899 RKDDAQQRSWALY(ph)EDEGVIR ddPTM_HeLa_Curcumin_4h_R1 1 RKDDAQQRSWALYEDEGVIR 20 3 Q9NZQ3-5;Q9NZQ3-4;Q9NZQ3-3;Q9NZQ3-2;Q9NZQ3;H7C2K2 Q9NZQ3-5 NCKIPSD NCK-interacting protein with SH3 domain 1 0 RKDDAQQRS(0.101)WALY(0.899)EDEGVIR 63.894 0.0054806 50226000 1296 1211.5 1468.5 1342.9 1485.2 1644.1 1125.1 929.73 1555.4 1456.2 TRUE FALSE FALSE 1193.420232 1316.216662 1522.923902 1337.343436 1467.48996 1303.095127 1156.667278 1213.200397 1384.776511 1506.802842 0.79202149 0.87351618 1.010698852 0.887537108 0.973909738 0.864807984 0.767630141 0.805148732 0.919016392 1 10.55727494 -9.566511772 1.347995985 0.99988451 0.865782874 0.143660836 0.075878303 0.462490096 1.50838738 0.056051795 0.013216443 2.71E-10 9.566511772 -0.134101635 RKDPELWGSVLLESNPYR ddPTM_HeLa_Curcumin_4h_R1 2 RKDPELWGSVLLESNPYR 18 2 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 ; ; 92.096 0.00094798 32151000 8684.6 7678.4 8004.4 6784.8 7544.5 15152.2 11062.1 9345.8 9041.7 9756 FALSE FALSE TRUE 7997.204746 8342.086682 8301.050105 6756.726295 7454.536765 12009.46292 11372.47275 12195.2914 8049.848131 10095.02027 0.792193035 0.826356605 0.822291573 0.669312801 0.738437028 1.189642278 1.126542835 1.208050214 0.797407822 1 13.30135619 -5.249464882 24.93369837 0.860512108 1.169924915 0.754618755 0.092691835 398.8695791 830537.7328 0.016984182 0.042924289 5.63E-06 5.249464882 0.309412806 RKDSEEEAAS(ph)PEGK ddPTM_HeLa_Curcumin_4h_R1 1 RKDSEEEAASPEGK 14 2 A0A3B3ITU7;Q9HB96 A0A3B3ITU7 FANCE Fanconi anemia group E protein 1 0 RKDS(0.001)EEEAAS(0.999)PEGK 100.45 0.0036888 10896000 4032.1 3430.1 3890.8 3693.9 3366.5 3953.9 2562.2 1670.6 4066.3 3915.7 TRUE FALSE FALSE 3712.95503 3726.58256 4034.996471 3678.615621 3326.356686 3133.81657 2634.088436 2179.95825 3620.237063 4051.770284 0.916378464 0.919741816 0.995860127 0.907903302 0.82096379 0.773443791 0.65010804 0.538026121 0.893495142 1 11.98433667 -4.316832321 0.576747292 0.965293836 0.251635793 0.930708444 0.037372706 0.55618842 0.129582321 0.007090348 0.260744522 4.82E-05 4.316832321 -0.713658043 RKEDEVEEWQHR ddPTM_HeLa_Curcumin_4h_R1 3 RKEDEVEEWQHR 12 2 E7EQR4;P15311 E7EQR4 EZR Ezrin 0 0 ;; ;; 96.229 0.0039467 36513000 14082 11106 11691.9 13524.9 12970.8 15637.7 11992.1 12325.9 14042.6 12438.9 FALSE FALSE TRUE 12967.39484 12065.95315 12125.2121 13468.93755 12816.13168 12394.26475 12328.56605 16084.01017 12502.16191 12871.15085 1.007477497 0.93744167 0.942045684 1.04644392 0.995725389 0.962949226 0.957844889 1.249617098 0.971332094 1 13.65185343 -4.25673616 24.99660411 0.992442552 1.249617202 0.850062157 0.033596935 140.7205362 747873.2377 0.004717772 0.051231041 5.54E-05 4.25673616 0.25717465 RKELEEVS(ph)PETPVVPATTQR ddPTM_HeLa_Curcumin_4h_R1 3 RKELEEVSPETPVVPATTQR 20 2 Q15149 Q15149 PLEC Plectin 1 0 RKELEEVS(0.958)PET(0.041)PVVPATT(0.001)QR;RKELEEVS(0.997)PET(0.003)PVVPATTQR;RKELEEVS(0.945)PET(0.055)PVVPATTQR ;; 64.843 0.0029105 107860000 8616 6750.6 7584.4 8351.5 6765.3 8922 7001.2 6718.2 8993.7 7348.8 TRUE FALSE FALSE 7934.034508 7334.091784 7865.484536 8316.943706 6684.628216 7071.476628 7197.634829 8766.548253 8007.113611 7604.170253 1.043379388 0.964482848 1.034364602 1.093734547 0.879073981 0.929947173 0.946537832 1.152860596 1.052989786 1 12.89257512 -5.77663832 24.99968557 1.022029621 0.971553084 0.106027525 0.073679484 422.8836346 695571.5981 0.010434042 0.018965133 1.67E-06 5.77663832 -0.050476537 RKGLSVRS(ph)FGTESHVR ddPTM_HeLa_Curcumin_4h_R1 1 RKGLSVRSFGTESHVR 16 3 A0A1W2PR75;A0A1W2PQJ5;A0A1W2PQC6;A0A1W2PQ64;A0A1W2PQ27 A0A1W2PR75 1 0 RKGLSVRS(0.978)FGT(0.011)ES(0.011)HVR 70.47 0.0072294 0 1007.1 695.08 966.98 912.73 943.89 1053.4 814.48 1115.9 1081.8 971.26 TRUE FALSE FALSE 927.3869723 755.159618 1002.817129 908.9533651 932.6347282 834.9129657 837.3321167 1456.132773 963.1292465 1005.011213 0.922762812 0.751394222 0.997816857 0.904421119 0.927984401 0.830749901 0.83315699 1.448872166 0.958326867 1 9.972995882 -4.254930863 24.98612562 0.929311125 1.448872402 0.809097866 0.078619588 265.4534072 1019045.384 0.01174638 0.150428171 5.56E-05 4.254930863 0.519561277 RKGS(ph)GS(ph)EQEGEDEEGGER ddPTM_HeLa_Curcumin_4h_R1 3 RKGSGSEQEGEDEEGGER 18 2 Q6PD62 Q6PD62 CTR9 RNA polymerase-associated protein CTR9 homolog 2 0 RKGS(1)GS(1)EQEGEDEEGGER;RKGS(1)GS(1)EQEGEDEEGGER;RKGS(1)GS(1)EQEGEDEEGGER ;; 79.635 0.0048184 190024000 20413 15830.7 17017.2 17965.8 17338.8 20538.6 16014.9 15357.5 19214.2 17487.2 TRUE FALSE FALSE 18797.28951 17199.03517 17647.8724 17891.46228 17132.04613 16278.66284 16464.23499 20039.93105 17106.45033 18094.8789 1.038818199 0.950491864 0.975296519 0.988758332 0.946789765 0.899628173 0.909883679 1.107491858 0.945375232 1 14.14329383 -7.256740624 24.87088686 1.018330816 0.963668347 0 0.059144429 457.828726 2423327.475 0.00888303 0.010681582 5.54E-08 7.256740624 -0.054662469 RKNSTDLDS(ph)APEDPTS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 RKNSTDLDSAPEDPTSPK 18 2 I3L2J0;A0A0A0MQR4;Q96RK0;I3L373;I3L135;I3L1Q4 I3L2J0 CIC Protein capicua homolog 2 0 RKNST(0.003)DLDS(0.985)APEDPT(0.29)S(0.721)PK 76.744 0.0062046 7789600 2436 2084.3 2538.3 2664.8 2711.1 3172.9 3254.4 3476.8 3090.7 2536.6 TRUE FALSE FALSE 2243.18803 2264.457605 2632.371631 2653.773764 2678.771903 2514.804774 3345.709705 4536.860315 2751.657943 2624.746661 0.854630301 0.862733778 1.002905031 1.011059011 1.020583031 0.958113334 1.274679097 1.728494556 1.048351821 1 11.35796247 -4.225631837 1.398962339 0.938305846 2.117255513 0.921282229 0.068309723 0.259882532 0.417827989 0.01070596 0.439349411 5.95E-05 4.225631837 1.178949667 RKPDTIEVQQMK ddPTM_HeLa_Curcumin_4h_R1 1 RKPDTIEVQQMK 12 2 P26038;P35241-4;E7EQR4;P15311 P26038;E7EQR4 MSN;EZR Moesin;Ezrin 0 0 47.302 0.017207 2196900 2491.1 1477.5 2036.8 1766.3 2069.2 2732.7 2267.8 2859.4 2247.5 1887.5 FALSE FALSE TRUE 2293.926806 1605.208516 2112.2856 1758.991519 2044.526141 2165.907216 2331.428365 3731.217897 2000.954873 1953.090485 1.174511281 0.821881285 1.081509339 0.900619573 1.046815884 1.108964092 1.193712418 1.910417324 1.024507 1 10.93154307 -4.165559621 2.096677794 1.050273761 2.302518115 0.87789006 0.098852603 0.265401137 1.025366736 0.01535734 0.682810745 6.83E-05 4.165559621 1.252244354 RST(ph)SPIIGS(ph)PPVR ddPTM_HeLa_Curcumin_4h_R1 1 RSTSPIIGSPPVR 13 1 Q86TB9-2;Q86TB9-4;Q86TB9 Q86TB9-2 PATL1 Protein PAT1 homolog 1 2 0 RS(0.388)T(0.534)S(0.078)PIIGS(1)PPVR 101.3 0.010029 44684000 2509.4 2317.1 2635.5 2943 2418 2599.3 1740.1 509.91 3046 2242.3 TRUE FALSE FALSE 2310.778342 2517.379799 2733.173948 2930.822646 2389.166929 2060.17588 1788.922523 665.3792117 2711.861421 2320.219758 0.99593081 1.084974727 1.177980637 1.263165972 1.029715793 0.887922738 0.771014261 0.28677422 1.168795073 1 11.18004574 -4.266226098 1.410345671 1.03836713 4.91E-13 0.855674764 0.10051934 0.372743198 0.651881174 0.015656106 0.544967615 5.42E-05 4.266226098 -1.03836713 down RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK ddPTM_HeLa_Curcumin_4h_R1 1 RKPVLPALTINPTIAEGPSPTSEGASEANLVDLQK 35 2 P36507 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 0 RKPVLPALTINPT(0.002)IAEGPS(0.884)PT(0.083)S(0.026)EGAS(0.005)EANLVDLQK 98.289 1.23E-11 63240000 3093.8 2623.6 2688.4 2789.3 2386.6 2714 1883.9 11182 3065.6 2615.7 TRUE FALSE FALSE 2848.922465 2850.372293 2788.034469 2777.758616 2358.141354 2151.085807 1936.757164 14591.34032 2729.31135 2706.59538 1.052585283 1.053120948 1.030089126 1.026292528 0.871257437 0.794757067 0.715569522 5.391031268 1.008392821 1 11.40226351 -4.259298772 24.99997702 0.986588504 5.39103278 0.992365187 0.116815499 12.0548467 140777.6561 0.017566097 0.155311613 5.50E-05 4.259298772 4.404444276 RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK ddPTM_HeLa_Curcumin_4h_R1 1 RKPVLPALTINPTIAEGPSPTSEGASEANLVDLQK 35 2 P36507 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 0 RKPVLPALTINPTIAEGPS(0.406)PT(0.553)S(0.04)EGASEANLVDLQK 90.03 2.42E-09 85492000 3030.4 2317.6 2340.5 2780.9 2370.7 2473.3 1959.7 11446 3194.4 2779.6 TRUE FALSE FALSE 2790.540642 2517.923017 2427.240989 2769.393373 2342.430951 1960.3097 2014.683908 14935.83271 2843.982312 2876.190893 0.970220944 0.875436684 0.843908169 0.962868417 0.814421239 0.681564532 0.700469469 5.192921216 0.988801654 1 11.48994372 -4.259641587 24.99999971 0.921302994 5.192922647 0.991693435 0.118587435 11.07949581 154058.092 0.018981582 0.163780666 5.50E-05 4.259641587 4.271619652 RKS(ph)GGNEVSIEER ddPTM_HeLa_Curcumin_4h_R1 1 RKSGGNEVSIEER 13 2 Q15061 Q15061 WDR43 WD repeat-containing protein 43 1 0 RKS(1)GGNEVSIEER 54.524 0.017867 34338000 2511.7 2138.9 2048.7 2573.4 2610.8 3741.9 2447.6 1303.3 3082.2 2399.3 TRUE FALSE FALSE 2312.896295 2323.776985 2124.626624 2562.751953 2579.667915 2965.78776 2516.273069 1700.67017 2744.090371 2482.675496 0.931614421 0.935997068 0.855781042 1.032254097 1.039067699 1.194593399 1.013532809 0.685015087 1.105295628 1 11.27767999 RKS(ph)HEAEVLK ddPTM_HeLa_Curcumin_4h_R1 3 RKSHEAEVLK 10 2 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 1 0 RKS(1)HEAEVLK;RKS(1)HEAEVLK;RKS(1)HEAEVLK ;; 91.658 0.0052636 115885000 19031.1 25916.3 17393.3 15039.1 15112.8 25551.8 17843.3 5683.8 15213.6 17734.4 TRUE FALSE FALSE 17524.76835 28156.38949 18037.911 14976.87219 14932.58973 20252.06865 18343.93498 7416.764455 13544.70614 18350.66908 0.954993427 1.534352201 0.982956584 0.816148562 0.813735437 1.103614727 0.999633032 0.404168612 0.738104212 1 14.16354505 -6.362823697 5.822332069 1.030059849 0.852250156 0.150550844 0.252091969 0.402971602 19.29763047 0.03631325 0.055745054 4.34E-07 6.362823697 -0.177809692 RKS(ph)LSDSESDDS(ph)KSK ddPTM_HeLa_Curcumin_4h_R1 1 RKSLSDSESDDSKSK 15 3 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 2 0 RKS(0.923)LS(0.076)DS(0.001)ES(0.001)DDS(0.705)KS(0.294)K 76.678 0.015499 5850500 4541.9 3435.9 3029.1 3480.5 3207.4 4271.8 2827.5 3620 5155.9 4256.3 TRUE FALSE FALSE 4182.403822 3732.883886 3141.361111 3466.098613 3169.15385 3385.780527 2906.83204 4723.721336 4590.310669 4404.206108 0.949638532 0.847572478 0.713263874 0.786997368 0.719574373 0.76876069 0.660012717 1.072547746 1.042256097 1 12.10466627 -7.194058147 2.436516466 0.978933975 0.777007342 0.432598235 0.106774027 0.188748445 2.151012672 0.01704111 0.020711961 6.40E-08 7.194058147 -0.201926632 LLGHS(ph)PVLR ddPTM_HeLa_Curcumin_4h_R1 2 LLGHSPVLR 9 0 G8JLH2;B4DIG0;P30305-2;P30305;P30305-4 G8JLH2 CDC25B M-phase inducer phosphatase 2 1 0 LLGHS(1)PVLR;LLGHS(1)PVLR ; 72.289 0.020081 18479200 8471.6 7395.9 7116 6599.4 6843 9579.4 6458 2331.7 8456.5 6398.1 TRUE FALSE FALSE 7801.063921 8035.168641 7379.72522 6572.093431 6761.401694 7592.524458 6639.194099 3042.624596 7528.843107 6620.433499 1.178331286 1.213692222 1.114689124 0.992698353 1.021292895 1.14683192 1.002833742 0.459580871 1.13721301 1 12.69270997 -4.266207611 3.433603258 1.089566503 0.383241157 0.875612494 0.071971908 0.089456287 1.786099548 0.012194536 0.163316937 5.42E-05 4.266207611 -0.706325346 down RKS(ph)QVNGEAGSYEMTNQHVK ddPTM_HeLa_Curcumin_4h_R1 1 RKSQVNGEAGSYEMTNQHVK 20 2 Q05D32;H0YMH7;Q05D32-2 Q05D32 CTDSPL2 CTD small phosphatase-like protein 2 1 0 RKS(0.874)QVNGEAGS(0.097)Y(0.029)EMTNQHVK 53.504 0.0078685 19573000 2628.9 2007.1 2069.9 2329.8 2406.3 2379.3 1418.9 1972.3 3118 2091.9 TRUE FALSE FALSE 2420.819791 2180.584781 2146.612315 2320.159905 2377.606444 1885.80636 1458.710515 2573.645191 2775.963201 2164.593369 1.118371619 1.007387721 0.991693103 1.071868711 1.098407894 0.871205829 0.673895862 1.188973979 1.282440961 1 11.07988032 -5.254977456 24.69927964 1.052109827 0.887612274 0.205461249 0.143215021 425.6658697 1627007.016 0.016242078 0.040319979 5.56E-06 5.254977456 -0.164497553 RKSDKNPNSPR ddPTM_HeLa_Curcumin_4h_R1 1 RKSDKNPNSPR 11 3 K7EKG9;Q14CW9 K7EKG9 ATXN7L3 Ataxin-7-like protein 3 0 0 93.667 0.01797 2315700 619.8 593.74 582.75 418.85 454.55 705.29 503.23 462.14 644.25 407.36 FALSE FALSE TRUE 570.742176 645.0602399 604.3472276 417.1169097 449.1297881 559.0049037 517.3492794 603.0443586 573.5773868 421.5157297 1.354023434 1.530334919 1.433747747 0.98956428 1.065511336 1.326178039 1.227354623 1.430656832 1.360749662 1 8.719442659 -9.291957442 1.075897624 1.003821534 1.290550298 0 0.191755973 0.512574061 1.083823101 0.107283481 0.030408185 5.11E-10 9.291957442 0.286728764 RKSLVGT(ph)PYWMAPELISR ddPTM_HeLa_Curcumin_4h_R1 1 RKSLVGTPYWMAPELISR 18 2 O96013;M0R1R1;O96013-2;O96013-3;O96013-4 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 0 RKS(0.21)LVGT(0.413)PY(0.378)WMAPELISR 70.501 0.0060228 23098000 1997.8 1851 1764.3 2005.9 1659.9 3103.8 1954.5 2183.7 2601.5 2433 TRUE FALSE FALSE 1839.672022 2010.992192 1829.68651 1997.600117 1640.106777 2460.036893 2009.33801 2849.500077 2316.121959 2517.546569 0.730740017 0.798790464 0.72677365 0.79347097 0.651470283 0.97715646 0.798133403 1.131855956 0.919991704 1 11.29780275 -4.256425622 24.31414592 0.838972795 1.131856137 0.418746469 0.107889584 344.456478 1670352.811 0.017880157 0.19729121 5.54E-05 4.256425622 0.292883341 RKT(ph)SSDDES(ph)EEDEDDLLQR ddPTM_HeLa_Curcumin_4h_R1 1 RKTSSDDESEEDEDDLLQR 19 2 Q9Y5J1 Q9Y5J1 UTP18 U3 small nucleolar RNA-associated protein 18 homolog 2 0 RKT(0.878)S(0.078)S(0.044)DDES(0.999)EEDEDDLLQR 81.65 0.020359 9855100 4003.1 2760.3 3283.4 3796 3780.9 4119.9 3216.6 2873.5 4085.8 3293.5 TRUE FALSE FALSE 3686.250411 2998.888032 3405.085692 3780.293158 3735.815237 3265.386299 3306.849139 3749.616922 3637.597962 3407.94888 1.081662472 0.879968608 0.99915985 1.109257589 1.09620636 0.958167629 0.970334138 1.100256211 1.067386305 1 11.73468798 -9.922970095 2.152858821 0.999640048 1.033431413 0 0.074313303 1.269201248 10.65885887 0.058099843 0.011067042 1.19E-10 9.922970095 0.033791365 QLPLEPES(ph)PSGQVGPRPAPPQEESPSSEAK ddPTM_HeLa_Curcumin_4h_R1 2 QLPLEPESPSGQVGPRPAPPQEESPSSEAK 30 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 QLPLEPES(0.493)PS(0.493)GQVGPRPAPPQEES(0.006)PS(0.004)S(0.004)EAK;QLPLEPES(0.5)PS(0.5)GQVGPRPAPPQEES(0.001)PSSEAK ; 77.51 1.01E-05 87016000 2152.79 1755.72 2102.86 2308.15 1846.75 3042.5 3062.2 6180.9 2617.98 2345.21 TRUE FALSE FALSE 1982.3944 1907.476613 2180.793841 2298.599487 1824.728712 2411.451204 3148.117091 8065.427957 2330.794144 2426.705873 0.816907571 0.786035355 0.898664262 0.94720976 0.751936497 0.993713837 1.297280039 3.323611669 0.960476574 1 11.24478354 -4.217785114 2.426890899 0.896482567 4.05040341 0.987250131 0.082418002 0.056031937 0.361673886 0.013584505 0.38350032 6.06E-05 4.217785114 3.153920842 up RKTS(ph)SDDES(ph)EEDEDDLLQR ddPTM_HeLa_Curcumin_4h_R1 2 RKTSSDDESEEDEDDLLQR 19 2 Q9Y5J1 Q9Y5J1 UTP18 U3 small nucleolar RNA-associated protein 18 homolog 2 0 RKT(0.451)S(0.548)S(0.017)DDES(0.985)EEDEDDLLQR;RKT(0.384)S(0.459)S(0.157)DDES(1)EEDEDDLLQR ; 89.201 0.0016196 50246000 11115.5 8787.5 9295.1 10957.6 9214.4 12642 8958.9 7622.6 12330.6 10486.3 TRUE FALSE FALSE 10235.69645 9547.052344 9639.584583 10912.26035 9104.524298 10019.9067 9210.262622 9946.69565 10977.96403 10850.69814 0.943321463 0.879856044 0.888383812 1.005673571 0.839072673 0.923434286 0.848817514 0.916687159 1.01172882 1 13.40550025 -8.210262896 0.331648677 1.018850463 0.883980266 0.45851558 0.044532058 1.110180057 0.298852561 0.05985857 0.027830329 6.16E-09 8.210262896 -0.134870197 RLAAAEETAVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 RLAAAEETAVSPR 13 1 Q9BUH6 Q9BUH6 C9orf142 Protein PAXX 1 0 RLAAAEETAVS(1)PR;RLAAAEETAVS(1)PR;RLAAAEETAVS(1)PR;RLAAAEETAVS(1)PR ;;; 130.47 0.00075961 301512800 6655.4 6250.8 5929.3 6770 6488.4 9024.7 7009 6097.6 7460.9 6061.4 TRUE FALSE FALSE 6128.618067 6791.091299 6149.045074 6741.987534 6411.030068 7152.875491 7205.653676 7956.73017 6642.457936 6272.033199 0.977134188 1.08275755 0.980391028 1.074928547 1.022161373 1.140439673 1.148854518 1.2686046 1.059059754 1 12.61471748 -1.000000409 0.377524946 0.988633816 5.004686396 0.771735286 0.04123176 13.48158063 0.164175766 0.008475485 40.0054098 0.099999906 1.000000409 4.01605258 RLAAQESS(ph)ETEDMSVPR ddPTM_HeLa_Curcumin_4h_R1 1 RLAAQESSETEDMSVPR 17 1 Q641Q2;F8W7U3;E7ESD2;Q641Q2-2;A0A087WYF6 Q641Q2 FAM21A WASH complex subunit FAM21A 1 0 RLAAQES(0.054)S(0.89)ET(0.054)EDMS(0.001)VPR 71.309 0.0084946 9764600 551.1 499.07 422.8 484.27 517.58 552.03 625.42 353.55 620.22 691.57 TRUE FALSE FALSE 507.4798535 542.207387 438.4693399 482.2662191 511.4081965 437.5327553 642.967602 461.3457675 552.1834177 715.602006 0.70916494 0.757694057 0.612727936 0.673930781 0.714654504 0.611419129 0.898498881 0.644696023 0.77163481 1 9.483013621 -9.101888116 0.657135818 1.02359556 0.700006769 0.223222846 0.104952802 0.403649174 0.284947342 0.073366317 0.016737378 7.91E-10 9.101888116 -0.323588792 TLS(ph)TSDDVEDRENEK ddPTM_HeLa_Curcumin_4h_R1 1 TLSTSDDVEDRENEK 15 1 Q96A65;Q96A65-2 Q96A65 EXOC4 Exocyst complex component 4 1 0 T(0.047)LS(0.803)T(0.137)S(0.013)DDVEDRENEK 70.117 0.012839 11184000 1266.1 970.27 1097.6 1108.1 957.06 1700.7 2323.7 7019.2 0 903.59 TRUE FALSE FALSE 1165.886849 1054.135815 1138.278022 1103.514976 945.6476846 1347.955649 2388.896768 9159.321768 0 934.9896852 1.246951563 1.127430422 1.217423079 1.180242941 1.011399056 1.4416797 2.554997992 9.796174131 0 1 9.868806639 -4.21774211 2.439070762 1.139727879 12.37450065 0.97893061 0.383920961 0.026660901 0.174447905 0.023204979 0.652267886 6.06E-05 4.21774211 11.23477277 up RLAEDEAFQR ddPTM_HeLa_Curcumin_4h_R1 1 RLAEDEAFQR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 158.47 0.00091363 11399000 1746.6 1197.6 1163.2 1208.5 1399.3 1891.3 1443.9 1209.1 1735.8 1175.9 FALSE FALSE TRUE 1608.354767 1301.115208 1206.309215 1203.499547 1382.614261 1499.023061 1484.411948 1577.749024 1545.387083 1216.762437 1.321831376 1.069325587 0.991408987 0.989099852 1.136305838 1.231976773 1.219968584 1.296677951 1.270081189 1 10.24883181 -9.710031063 1.615081591 1.000182364 1.176449948 0 0.138410592 0.507121345 2.391063661 0.093628101 0.020671289 1.95E-10 9.710031063 0.176267584 RLARVMDR ddPTM_HeLa_Curcumin_4h_R1 1 RLARVMDR 8 2 Q9GZZ6 Q9GZZ6 CHRNA10 Neuronal acetylcholine receptor subunit alpha-10 0 0 20.699 0.020363 2748500 2520.5 3435.3 2312.7 3385.1 1049.8 1386.3 1611.8 1405.6 2298.7 3995.3 FALSE FALSE TRUE 2320.999765 3732.232025 2398.410696 3371.093353 1037.281821 1098.765753 1657.02277 1834.160969 2046.538361 4134.136378 0.561423125 0.902783963 0.580147938 0.815428676 0.250906532 0.265778787 0.400814733 0.443662425 0.495034071 1 12.01337027 -10.18803613 0.098989755 1.866219981 7.68E-14 0.171926336 0.223012804 26.50007123 0.47679976 7.876428705 2.318014465 6.49E-11 10.18803613 -1.866219981 SEEPAGQILSHLS(ph)SELK ddPTM_HeLa_Curcumin_4h_R1 1 SEEPAGQILSHLSSELK 17 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 SEEPAGQILS(0.025)HLS(0.81)S(0.165)ELK 80.303 0.0043793 2355200 950.13 751.95 922.89 604.83 1102.6 1143.9 1120.3 1637.7 971.07 940.24 TRUE FALSE FALSE 874.9262079 816.9452074 957.0931153 602.3273737 1089.452215 906.6422456 1151.732603 2137.027191 864.5460505 972.91327 0.899284895 0.839689654 0.983739399 0.619096678 1.119783488 0.931883934 1.183797815 2.196523839 0.888615745 1 9.926167392 -4.217707868 2.255444373 0.931692437 2.609417758 0.906288802 0.123749401 0.143796026 0.761121075 0.016483297 0.497647264 6.06E-05 4.217707868 1.677725322 up GEGPGEAGGPLT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 GEGPGEAGGPLTPR 14 0 P50548;P50548-2 P50548 ERF ETS domain-containing transcription factor ERF 1 0 GEGPGEAGGPLT(1)PR;GEGPGEAGGPLT(1)PR;GEGPGEAGGPLT(1)PR;GEGPGEAGGPLT(1)PR ;;; 170.74 0.0005845 165427000 6003.2 4981.7 5341.7 5298.4 5080.42 7198.1 7955.4 12605.5 5972.4 5035.1 TRUE FALSE FALSE 5528.040385 5412.29595 5539.668101 5276.476625 5019.83931 5705.132921 8178.607113 16448.85892 5317.242662 5210.06935 1.061030097 1.03881457 1.063261874 1.012745948 0.963488002 1.095020534 1.569769338 3.157128594 1.020570419 1 12.34708686 -4.217612698 1.961302251 1.027330421 3.958417873 0.997262171 0.033540188 0.036340586 0.133285647 0.005843225 0.198816384 6.06E-05 4.217612698 2.931087452 up ILGSAS(ph)PEEEQEKPILDRPTR ddPTM_HeLa_Curcumin_4h_R1 1 ILGSASPEEEQEKPILDRPTR 21 2 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 0 ILGS(0.286)AS(0.714)PEEEQEKPILDRPTR 50.891 0.0087476 195700000 1128.3 825.47 1092 1292.5 1108.2 1716.5 1638.2 3586.1 1723.1 1325.7 TRUE FALSE FALSE 1038.993864 896.8199486 1132.470481 1287.151977 1094.985439 1360.478551 1684.163483 4679.485382 1534.080241 1371.767976 0.757412246 0.653769416 0.825555415 0.9383161 0.798229334 0.991770164 1.227732031 3.411280524 1.11832341 1 10.42182077 -4.217368678 2.558630149 0.86562102 4.127963782 0.971019957 0.130062558 0.065842286 0.491238459 0.017927706 0.483399429 6.06E-05 4.217368678 3.262342761 up SLLGDSAPTLHLNKGT(ph)PSQS(ph)PVVGR ddPTM_HeLa_Curcumin_4h_R1 1 SLLGDSAPTLHLNKGTPSQSPVVGR 25 1 C9J2I0;B8ZZY2;P52594-2;P52594-3;P52594;P52594-4 C9J2I0 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 2 0 SLLGDSAPT(0.001)LHLNKGT(0.936)PS(0.322)QS(0.74)PVVGR 77.276 0.00039856 301110000 3745.4 3212.7 3120.7 3437.7 3601.7 5140.9 3164.6 890.46 4379.9 3060.2 TRUE FALSE FALSE 3448.947638 3490.391472 3236.355887 3423.475708 3558.75208 4074.61939 3253.390159 1161.957155 3899.435928 3166.541722 1.089184334 1.102272377 1.022047448 1.08114025 1.123860789 1.286772684 1.027426904 0.366948317 1.231449408 1 11.62869237 -4.265372025 5.286892801 1.07030288 0.339430069 0.850737411 0.092009867 0.038980409 3.81914967 0.011709037 0.102844378 5.43E-05 4.265372025 -0.73087281 down RLAVPTEVSTEVPEMDT(ph)ST ddPTM_HeLa_Curcumin_4h_R1 1 RLAVPTEVSTEVPEMDTST 19 1 O00488 O00488 ZNF593 Zinc finger protein 593 1 0 RLAVPTEVSTEVPEMDT(0.415)S(0.327)T(0.258) 72.187 0.004684 13664000 596.12 538.56 499.57 656.6 576.44 615.14 503.92 465.98 637.75 582.39 TRUE FALSE FALSE 548.936473 585.1107266 518.0845037 653.8831632 569.5663295 487.5530299 518.058639 608.0551569 567.7904206 602.6280092 0.910904347 0.970931848 0.859708636 1.085052724 0.945137499 0.809044755 0.859665716 1.009005801 0.942190559 1 9.235123918 -7.50309331 0.010595481 1.889966438 3.06E-07 0.02507237 0.077293465 1644.649228 14.88802339 1331.313236 1322.748498 3.14E-08 7.50309331 -1.889966132 RLDEEEEDNEGGEWER ddPTM_HeLa_Curcumin_4h_R1 2 RLDEEEEDNEGGEWER 16 1 Q99613-2;Q99613 Q99613-2 EIF3C Eukaryotic translation initiation factor 3 subunit C 0 0 ; ; 249.36 2.09E-31 172239000 3937 3565.7 3225.4 3816.1 3763.2 4091.2 3106.4 2565.9 4286.4 4043.4 FALSE FALSE TRUE 3625.382296 3873.90322 3344.936161 3800.309989 3718.326298 3242.639003 3193.557224 3348.231098 3816.192644 4183.907849 0.866506249 0.925905483 0.799476538 0.908315892 0.888720888 0.775026392 0.763295306 0.800264064 0.912112021 1 12.03063536 -13.52287871 0.047077722 1.74725436 0.442952569 0.553494505 0.048878881 186.9878317 0.699064092 18.50854846 4.948605376 3.00E-14 13.52287871 -1.304301791 RLDEELEDAEK ddPTM_HeLa_Curcumin_4h_R1 1 RLDEELEDAEK 11 1 Q15008;Q15008-4;C9J7B7;C9J0E9;Q15008-3;Q15008-2 Q15008 PSMD6 26S proteasome non-ATPase regulatory subunit 6 0 0 196.02 2.70E-05 9622300 2260.4 2390.2 2812.3 2835.5 3763.3 3617.6 2767.8 2508.1 3080.7 2689.6 FALSE FALSE TRUE 2081.486955 2596.798237 2916.526312 2823.767452 3718.425105 2867.268981 2845.457019 3272.808144 2742.754918 2783.0634 0.747912159 0.933071894 1.047955398 1.014625629 1.336090693 1.030256437 1.022419043 1.175973262 0.985516506 1 11.44245806 -6.628430225 2.08888332 0.879962814 1.117525098 0.414993717 0.110165856 0.227026112 2.015613447 0.020877205 0.031360071 2.35E-07 6.628430225 0.237562284 RLDLPIER ddPTM_HeLa_Curcumin_4h_R1 1 RLDLPIER 8 1 B4E1E0;P17812-2;P17812;A0A3B3IRI2;A0A3B3ISY3;A0A3B3ITB8;A0A3B3IRQ8;A0A3B3ITF6 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 0 0 112.3 0.015568 19009000 2161.6 1717.3 1850.5 1737.5 2019.1 2396.4 1846.7 2253.7 2285.7 1966.3 FALSE FALSE TRUE 1990.507079 1865.73576 1919.081158 1730.310685 1995.023551 1899.359627 1898.513432 2940.842755 2034.964429 2034.628779 0.978314619 0.916990745 0.943209483 0.850430655 0.980534421 0.933516545 0.933100648 1.445395242 1.000164969 1 10.99054988 -4.259118747 24.99756626 0.965128205 1.445395409 0.913402822 0.045643283 48.16389771 518782.1417 0.006995606 0.06254241 5.51E-05 4.259118747 0.480267204 RLDQLER ddPTM_HeLa_Curcumin_4h_R1 1 RLDQLER 7 1 M0R2F5;Q96CT7 M0R2F5 CCDC124 Coiled-coil domain-containing protein 124 0 0 110.41 0.0039527 0 1380.3 1155.4 1195.4 1084.4 1389.5 1901.4 1285.2 1181 1129.4 1321.5 FALSE FALSE TRUE 1271.047799 1255.267628 1239.702576 1079.91304 1372.93112 1507.028207 1321.259253 1541.081463 1005.507646 1367.422027 0.929521226 0.917981138 0.906598366 0.78974378 1.004028817 1.102094436 0.966241019 1.126997689 0.735330883 1 10.41724285 -5.525808839 24.99866873 0.943854082 1.054863659 0.349548358 0.093773738 76.32741242 651201.8859 0.010404621 0.020901572 2.98E-06 5.525808839 0.111009577 RLDSDAVNTIESQS(ph)VSPDHNKEPK ddPTM_HeLa_Curcumin_4h_R1 1 RLDSDAVNTIESQSVSPDHNKEPK 24 2 Q3T7B4;Q9H3H1-6;Q9H3H1-3;Q9H3H1-2;Q9H3H1-5;Q9H3H1-4;Q9H3H1 Q3T7B4 TRIT1 "tRNA dimethylallyltransferase, mitochondrial" 1 0 RLDSDAVNTIES(0.152)QS(0.487)VS(0.361)PDHNKEPK 60.272 0.0016789 9684400 1513.3 1155.6 1668.7 1508.8 1454.7 1868.1 1177.8 1045.1 2050 1559.3 TRUE FALSE FALSE 1393.520708 1255.484915 1730.54349 1502.556985 1437.353653 1480.635002 1210.845898 1363.746179 1825.120129 1613.485559 0.863671014 0.77811971 1.072549723 0.931249107 0.890837631 0.917662383 0.750453508 0.845217468 1.131166076 1 10.65596495 -13.52287875 0.228068423 1.660969 0.863036511 0.349477103 0.09296342 56.58040633 0.726641879 16.77420743 0.063978102 3.00E-14 13.52287875 -0.79793249 RLDSDAVNTIESQSVS(ph)PDHNKEPK ddPTM_HeLa_Curcumin_4h_R1 1 RLDSDAVNTIESQSVSPDHNKEPK 24 2 Q3T7B4;Q9H3H1-6;Q9H3H1-3;Q9H3H1-2;Q9H3H1-5;Q9H3H1-4;Q9H3H1 Q3T7B4 TRIT1 "tRNA dimethylallyltransferase, mitochondrial" 1 0 RLDSDAVNTIES(0.043)QS(0.202)VS(0.755)PDHNKEPK 66.467 0.00039037 8629100 2496.7 1697.5 2119.1 1722.9 2090.8 2441.3 2022.7 1196.6 2120.2 1760.7 TRUE FALSE FALSE 2299.08356 1844.224336 2197.63571 1715.771096 2065.868576 1934.946861 2079.451518 1561.437832 1887.619364 1821.884194 1.261926289 1.012262109 1.206243359 0.941756398 1.13391871 1.062058097 1.141374147 0.8570456 1.036080872 1 10.83121554 -6.268321754 24.90572082 1.122328445 1.041433879 0.085907083 0.111332057 1032.280317 3735581.546 0.019126222 0.029607619 5.39E-07 6.268321754 -0.080894566 RLEDAFIVIS(ph)DS(ph)DGEEPKEENGLQK ddPTM_HeLa_Curcumin_4h_R1 1 RLEDAFIVISDSDGEEPKEENGLQK 25 2 Q96RL1-2;Q96RL1;D6RC40;D6RCQ3;Q96RL1-5;D6RDZ5 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 2 0 RLEDAFIVIS(1)DS(1)DGEEPKEENGLQK 43.956 0.018578 4258200 839.12 700.4 754.61 653.18 653.2 967.55 677.55 533.71 710.87 778.84 TRUE FALSE FALSE 772.7027666 760.9394551 782.5765104 650.4773142 645.4110166 766.8692235 696.5602295 696.4357221 632.8893395 805.904632 0.958801744 0.944205338 0.971053496 0.807139317 0.800852844 0.951563241 0.864320916 0.864166422 0.785315426 1 9.654465315 -6.283211534 21.8811518 0.976100334 0.860048091 0.069813768 0.072818772 77.37955824 77766.78065 0.006632355 0.010140957 5.21E-07 6.283211534 -0.116052244 RLEEEADR ddPTM_HeLa_Curcumin_4h_R1 1 RLEEEADR 8 1 A0A669KAX4;K4DI93;Q13620-1;Q13620;Q13620-3 A0A669KAX4 CUL4B Cullin-4B 0 0 117.81 0.013126 2356600 1270.7 1215.7 1160.3 1200.6 1212.8 1463.8 885.92 1051.5 1239.6 1566.7 FALSE FALSE TRUE 1170.122754 1320.779691 1203.301739 1195.632235 1198.338152 1160.19138 910.7765309 1372.097509 1103.618981 1621.142708 0.721788864 0.814721421 0.742255282 0.737524358 0.7391935 0.715662707 0.561811447 0.846376758 0.680766089 1 10.66279538 -10.20543587 0.344160219 1.234233901 0.707143815 0 0.123503739 2.320433169 0.215215009 0.501333133 0.026019472 6.23E-11 10.20543587 -0.527090087 RLEEETEYLNS(ph)QLEDAIR ddPTM_HeLa_Curcumin_4h_R1 2 RLEEETEYLNSQLEDAIR 18 1 Q8TD16;Q8TD16-2 Q8TD16 BICD2 Protein bicaudal D homolog 2 1 0 RLEEETEYLNS(1)QLEDAIR;RLEEETEYLNS(1)QLEDAIR ; 143.58 0.00011001 3840400 1610.62 1314.34 1566.03 1665.63 1200.29 1723.91 1509.59 1876.64 1669.89 1540.13 TRUE FALSE FALSE 1483.137727 1427.945693 1624.068449 1658.738064 1185.977326 1366.351634 1551.945033 2448.818897 1486.707245 1593.649403 0.930654964 0.896022482 1.019087665 1.040842522 0.744189609 0.857372789 0.9738309 1.536610808 0.932894802 1 10.63811856 -4.262896659 5.483006894 0.9476059 1.557842391 0.825147213 0.08322252 0.04638631 5.323598929 0.011970202 0.105819975 5.46E-05 4.262896659 0.61023649 RLEEIPLIK ddPTM_HeLa_Curcumin_4h_R1 2 RLEEIPLIK 9 1 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 ; ; 133.23 0.00012511 2356600 2054.23 2013.2 2188.1 2422 2637.7 2186.6 2227.4 2003.57 2320.07 2504.4 FALSE FALSE TRUE 1891.635528 2187.212037 2269.192911 2411.978406 2606.24715 1733.074512 2289.894849 2614.44927 2065.564126 2591.427714 0.729958825 0.844018155 0.875653563 0.930752725 1.005718638 0.668772084 0.883642186 1.008883735 0.797075726 1 11.33953144 -6.510989267 22.92644441 0.866452023 0.892892364 0.037793713 0.109414096 1264.157317 2437669.592 0.020607875 0.030424197 3.08E-07 6.510989267 0.026440341 RLEEPEEPK ddPTM_HeLa_Curcumin_4h_R1 3 RLEEPEEPK 9 1 O75822-2;O75822 O75822-2 EIF3J Eukaryotic translation initiation factor 3 subunit J 0 0 ;; ;; 110.53 0.0023663 9576600 10229.1 9007.1 8729.7 9940 9991.6 11734.7 9615.4 9087.2 9831.1 8867.8 FALSE FALSE TRUE 9419.455941 9785.633589 9053.230361 9898.870914 9872.456696 9300.790943 9885.182245 11857.84545 8752.652926 9175.95539 1.026536806 1.066443021 0.986625368 1.078783679 1.075905045 1.013604638 1.077291881 1.292273659 0.953868295 1 13.16364266 -4.246060943 2.501610979 1.024010389 1.357713975 0.813677386 0.038204232 0.147145159 1.101934528 0.004653203 0.105770333 5.67E-05 4.246060943 0.333703586 RLEEPEEPKVLT(ph)PEEQLADK ddPTM_HeLa_Curcumin_4h_R1 1 RLEEPEEPKVLTPEEQLADK 20 2 O75822-2;O75822 O75822-2 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 0 RLEEPEEPKVLT(1)PEEQLADK 90.475 0.00048709 17408000 5156.1 4411.5 4667.6 5257.2 5350.3 6736.9 6141.9 4872.2 5507.6 4629.6 TRUE FALSE FALSE 4747.989244 4792.810403 4840.585362 5235.447099 5286.501167 5339.590999 6314.225184 6357.711351 4903.430059 4790.478255 0.991130528 1.00048683 1.010459729 1.0928861 1.103543505 1.114625871 1.318078248 1.327155873 1.023578398 1 12.22595398 -4.618913344 0.639555767 0.994455664 1.49472671 0.928543103 0.032190621 0.334522879 0.122404353 0.005220197 0.111402722 2.40E-05 4.618913344 0.500271046 RLEEPEEPKVLT(ph)PEEQLADKLR ddPTM_HeLa_Curcumin_4h_R1 1 RLEEPEEPKVLTPEEQLADKLR 22 3 O75822-2;O75822 O75822-2 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 0 RLEEPEEPKVLT(1)PEEQLADKLR 47.016 0.012381 11871000 1734.2 1318.2 1467.8 1622.2 1441.5 2497.7 1694.1 1655.5 2232.7 1736.8 TRUE FALSE FALSE 1596.93624 1432.139334 1522.197959 1615.487766 1424.311054 1979.648865 1741.631887 2160.254329 1987.778396 1797.153671 0.888591925 0.796893086 0.847004897 0.898914652 0.792537153 1.101546794 0.969105711 1.202042076 1.106070354 1 10.81149806 -5.236883543 24.6119688 0.914298394 1.078718978 0.40466078 0.102908567 509.2016371 510364.505 0.013132685 0.033463151 5.80E-06 5.236883543 0.164420585 RLEEWLGR ddPTM_HeLa_Curcumin_4h_R1 1 RLEEWLGR 8 1 P56192;P56192-2 P56192 MARS "Methionine--tRNA ligase, cytoplasmic" 0 0 102.62 0.019808 19765000 3932.4 3495.3 3774.2 3231.4 3710.3 4719.8 3751.6 2655.8 3855.9 3611.9 FALSE FALSE TRUE 3621.146391 3797.418157 3914.075172 3218.029323 3666.057096 3740.860277 3856.859799 3465.541194 3432.917417 3737.413256 0.968891087 1.016055196 1.047268499 0.861031174 0.980907608 1.000922301 1.031959683 0.927256623 0.91852765 1 11.86782438 RLEIS(ph)PDSS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 RLEISPDSSPER 12 1 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 2 0 RLEIS(0.997)PDS(0.067)S(0.935)PER 115.26 0.0023284 0 3019.2 2566.6 2704.8 2857.5 2519.8 2730.8 1945.8 1478.8 3026.4 2468.9 TRUE FALSE FALSE 2780.227134 2788.445467 2805.042267 2845.676422 2489.753031 2164.401298 2000.393911 1929.679312 2694.411492 2554.694091 1.08828182 1.091498774 1.097995364 1.113901047 0.974579712 0.847225233 0.783026789 0.755346528 1.054690462 1 11.31893483 -5.242749926 2.087793883 1.055953454 0.770996245 0.926697633 0.035187344 0.0836353 0.69927592 0.006996208 0.021854396 5.72E-06 5.242749926 -0.284957209 RLFDDEAS(ph)VDEPR ddPTM_HeLa_Curcumin_4h_R1 3 RLFDDEASVDEPR 13 1 A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;A0A0U1RR46;A0A0X1KG69;A0A087WUZ6;Q8NI35-5 A0A2R8Y549 INADL InaD-like protein 1 0 RLFDDEAS(1)VDEPR;RLFDDEAS(1)VDEPR;RLFDDEAS(1)VDEPR ;; 127.32 0.00085843 17164300 5453.7 4455.7 5458.3 5383.9 5061.8 7375.5 5217.1 5129.2 6106.5 5261 TRUE FALSE FALSE 5022.03389 4840.830854 5660.5894 5361.622848 5001.441341 5845.738161 5363.477785 6693.069468 5436.632228 5443.819358 0.922520304 0.889234292 1.039819477 0.984900948 0.918737565 1.073830297 0.98524169 1.229480449 0.998679763 1 12.41040348 -1.000000015 0.934140922 0.963209093 164.2085372 0.656367128 0.053994552 488.3607946 0.876684785 0.008322885 170273.9856 0.099999996 1.000000015 163.2453281 RLGDS(ph)SLSR ddPTM_HeLa_Curcumin_4h_R1 1 RLGDSSLSR 9 1 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 0 RLGDS(0.5)S(0.5)LSR 109.16 0.014842 17988000 2903.7 2375.8 3084.9 2923.9 2532.7 3967.7 2526.7 3043.3 3904.6 3780.3 TRUE FALSE FALSE 2673.869081 2581.153566 3199.229108 2911.801677 2502.499207 3144.754295 2597.592402 3971.18816 3476.275149 3911.665144 0.683562877 0.659860563 0.817868859 0.7443893 0.639752922 0.803942613 0.66406308 1.015216798 0.888694462 1 11.93356716 -9.331878341 1.020798357 1.002152713 0.743539556 0.304922751 0.110063978 0.370278186 0.68182357 0.069939657 0.017836051 4.66E-10 9.331878341 -0.258613157 RLGDSS(ph)LSR ddPTM_HeLa_Curcumin_4h_R1 1 RLGDSSLSR 9 1 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 1 0 RLGDS(0.261)S(0.738)LSR 114.89 0.011924 40261000 6289.4 5083.3 5761.7 7028.6 5918.2 7044.6 4793.6 5718.1 6878.6 6142.8 TRUE FALSE FALSE 5791.587353 5522.677801 5975.233671 6999.517516 5847.62933 5583.470551 4928.095515 7461.522367 6124.034789 6356.261843 0.911162488 0.868856246 0.940054677 1.101200311 0.919979302 0.878420476 0.775313484 1.173885304 0.963464838 1 12.63396284 -9.460636603 1.244757307 0.999407664 0.936863791 0.00738079 0.10927344 1.312141946 3.690229096 0.068180056 0.017536591 3.46E-10 9.460636603 -0.062543872 RLGGLRPES(ph)PESLTSVSR ddPTM_HeLa_Curcumin_4h_R1 2 RLGGLRPESPESLTSVSR 18 2 Q9H6F5;H0YG79 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 1 0 RLGGLRPES(0.983)PES(0.007)LT(0.007)S(0.002)VSR;RLGGLRPES(0.986)PES(0.005)LT(0.005)S(0.002)VS(0.002)R ; 76.678 0.0061231 206153000 4572.8 3386.4 3640 4090.9 2940.9 4506.8 3584.7 2676.2 6007.8 4275.9 TRUE FALSE FALSE 4210.858055 3679.105326 3774.901602 4073.97294 2905.831688 3572.038878 3685.277034 3492.16106 5348.759371 4424.487207 0.95171663 0.831532595 0.853183979 0.920778556 0.656761236 0.807333983 0.832927492 0.789280406 1.208899274 1 12.11129454 -7.091162197 0.723025259 0.991504697 0.787804487 0.570711528 0.092133511 0.270242133 0.291816766 0.015091723 0.020137157 8.11E-08 7.091162197 -0.20370021 RLGSGPDRELRK ddPTM_HeLa_Curcumin_4h_R1 1 RLGSGPDRELRK 12 3 Q6NUJ5-2;Q6NUJ5 Q6NUJ5-2 PWWP2B PWWP domain-containing protein 2B 0 0 117.52 0.0013452 803340 424.19 645.09 465.13 471.7 864.26 1173.9 507.77 537.13 748.81 701.53 FALSE FALSE TRUE 390.6149139 700.8487051 482.368127 469.7482304 853.954264 930.4199074 522.0166596 700.8984644 666.6674164 725.9081153 0.538105176 0.965478537 0.664503009 0.647118031 1.176394431 1.28173234 0.719122226 0.965547085 0.918390913 1 9.503643135 -5.764008625 24.99993561 0.773899447 1.0306602 0.276859908 0.194399924 78.3079336 761983.3491 0.033520028 0.062850956 1.72E-06 5.764008625 0.256760752 RLGSLLPVLS(ph)PTSLPSPLPATLETPVPAFLK ddPTM_HeLa_Curcumin_4h_R1 2 RLGSLLPVLSPTSLPSPLPATLETPVPAFLK 31 1 P48681 P48681 NES Nestin 1 0 RLGS(0.011)LLPVLS(0.84)PT(0.03)S(0.096)LPS(0.023)PLPATLETPVPAFLK;RLGS(0.052)LLPVLS(0.3)PT(0.3)S(0.3)LPS(0.046)PLPAT(0.001)LETPVPAFLK ; 70.003 4.84E-05 67072000 3776.3 2851.9 3595.9 2260.15 1929.02 13302.3 5770.4 11434.1 4905.7 4047.6 TRUE FALSE FALSE 3477.40187 3098.405528 3729.167217 2250.798098 1906.017696 10543.25303 5932.301894 14920.30445 4367.556983 4188.253799 0.830274868 0.739784568 0.890387115 0.537407284 0.455086484 2.517338619 1.416414138 3.562416504 1.042810965 1 12.03213315 -3.11734714 0.751143154 0.861640092 15.36059288 0.738737658 0.478612864 4.320197601 0.475234869 0.071988209 78.85528963 0.000763225 3.11734714 14.49895279 RLKEDILENEDEQNS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 2 RLKEDILENEDEQNSPPK 18 2 Q9NTI5-2;Q9NTI5;A9IYQ1;Q9NTI5-5 Q9NTI5-2 PDS5B Sister chromatid cohesion protein PDS5 homolog B 1 0 RLKEDILENEDEQNS(1)PPK;RLKEDILENEDEQNS(1)PPK ; 68.944 0.0044341 28201000 7274.5 5422.1 6623.2 7890.9 7135 7705.4 6237 4965.5 8350.7 6766.6 TRUE FALSE FALSE 6698.715649 5890.762164 6868.661618 7858.249547 7049.919785 6107.213182 6411.993434 6479.458092 7434.649102 7001.738846 0.956721722 0.84132846 0.980993689 1.122328284 1.006881282 0.872242355 0.915771578 0.925406993 1.061828964 1 12.77349754 -5.264965888 24.98479399 0.981158396 0.905603435 0.245325008 0.070150892 374.4151853 2652688.473 0.009888284 0.022964803 5.43E-06 5.264965888 -0.075554961 RLLEDGEDFNLGDALDS(ph)SNSMQTIQK ddPTM_HeLa_Curcumin_4h_R1 2 RLLEDGEDFNLGDALDSSNSMQTIQK 26 1 P05783 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 RLLEDGEDFNLGDALDS(0.748)S(0.126)NS(0.126)MQTIQK;RLLEDGEDFNLGDALDS(0.333)S(0.333)NS(0.333)MQT(0.002)IQK ; 150.63 9.41E-09 36842800 3009.7 2547.49 2834.8 2857.71 2680.5 4554.7 3310.6 2648.7 3414.2 2997.6 TRUE FALSE FALSE 2771.479069 2767.683684 2939.860182 2845.885553 2648.536788 3610.003878 3403.486526 3456.276437 3039.670802 3101.766377 0.893516381 0.892292761 0.947801938 0.917504804 0.853880166 1.163854217 1.097273654 1.11429296 0.979980576 1 11.59887431 -5.253726739 24.99713367 0.936064103 1.122353623 0.80918641 0.04404022 234.7970646 760989.1878 0.007500976 0.018729407 5.58E-06 5.253726739 0.18628952 RLLEDGEDFNLGDALDSSNSMQTIQK ddPTM_HeLa_Curcumin_4h_R1 2 RLLEDGEDFNLGDALDSSNSMQTIQK 26 1 P05783 P05783 KRT18 "Keratin, type I cytoskeletal 18" 0 0 ; ; 114.35 2.73E-08 60211000 3268.2 2361.6 2630.79 3081.3 2558.88 3690.8 2597.6 2349.69 3896.8 2955.09 FALSE FALSE TRUE 3009.518521 2565.726181 2728.289392 3068.550397 2528.367027 2925.286476 2670.481665 3066.099664 3469.330789 3057.779158 0.984217096 0.839081585 0.892245401 1.003522569 0.826863844 0.956670291 0.873340267 1.002721095 1.134591679 1 11.5782685 -7.464932166 15.65217534 0.993038691 0.912827687 0.336709209 0.072887191 4.437885329 1198.436936 0.008938973 0.010203951 3.43E-08 7.464932166 -0.080211003 RLLS(ph)DSLPPSTGTFQEAQSR ddPTM_HeLa_Curcumin_4h_R1 1 RLLSDSLPPSTGTFQEAQSR 20 1 Q9Y490 Q9Y490 TLN1 Talin-1 1 0 RLLS(0.962)DS(0.037)LPPSTGTFQEAQSR 111.93 0.00044914 0 1000.3 643.49 659.39 657.97 492.33 690.79 630.03 597.49 1050.5 756.51 TRUE FALSE FALSE 921.1251995 699.1104083 683.8275735 655.2474945 486.4592863 547.5123672 647.7069462 779.6619505 935.2627782 782.7986662 1.176707676 0.893090955 0.873567627 0.8370575 0.621436018 0.699429356 0.827424693 0.995992947 1.194767976 1 9.612497488 -6.968794653 2.467378063 1.082841156 0.794297641 0.612514047 0.109430498 0.157694636 1.937664651 0.020065962 0.026423002 1.07E-07 6.968794653 -0.288543515 RLPDAHSDYAR ddPTM_HeLa_Curcumin_4h_R1 2 RLPDAHSDYAR 11 1 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 0 0 ; ; 135.8 0.0005731 7663800 2092.6 1116.9 1606.48 1499.87 1830.11 2045.07 1763.23 1560.68 1821.34 1594.36 FALSE FALSE TRUE 1926.968502 1213.439859 1666.017562 1493.663935 1808.287134 1620.899429 1812.701488 2036.524148 1621.543559 1649.763891 1.168026838 0.735523347 1.009852119 0.905380426 1.096088442 0.982503883 1.098764192 1.234433702 0.98289432 1 10.68804385 -4.353083606 3.016565441 1.034985034 1.248237116 0.234433643 0.116478795 0.408443829 5.779295979 0.017633584 0.183370751 4.44E-05 4.353083606 0.213252082 RLPNNHIGISFIPR ddPTM_HeLa_Curcumin_4h_R1 2 RLPNNHIGISFIPR 14 1 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 50.897 0.012553 7799200 4477.5 4220.7 5242.4 3290.22 6344.9 11276.7 7034.3 6270 4800.7 3844.5 FALSE FALSE TRUE 4123.10115 4585.518501 5436.687956 3276.605941 6269.241211 8937.785305 7231.663526 8181.694136 4274.075221 3978.096089 1.03645087 1.15269174 1.366655766 0.823661839 1.575940116 2.246749477 1.8178705 2.0566859 1.074402208 1 11.95786241 -5.544438725 4.274371358 1.047301847 2.010865157 0.874902597 0.163775757 0.045876854 1.962852496 0.022747526 0.048653379 2.85E-06 5.544438725 0.963563309 RLPQDHADS(ph)CVVS(ph)SDDEELSR ddPTM_HeLa_Curcumin_4h_R1 1 RLPQDHADSCVVSSDDEELSR 21 1 P78317;D6RA71 P78317 RNF4 E3 ubiquitin-protein ligase RNF4 2 0 RLPQDHADS(0.999)CVVS(0.533)S(0.461)DDEELS(0.006)R 56.416 0.0067388 16313000 3309.2 3227.9 3262.1 3127 3680.1 3899.3 2409.4 2532.5 3810.2 3133.5 TRUE FALSE FALSE 3047.273328 3506.905293 3382.996296 3114.061303 3636.217211 3090.541226 2477.001279 3304.647592 3392.230593 3242.388892 0.939823516 1.081580714 1.043365373 0.960421901 1.121462395 0.953167966 0.763943303 1.019201491 1.046213365 1 11.66284142 -4.990839469 24.9966713 0.994394684 0.883318184 0.256646615 0.081061167 206.6279362 563823.011 0.010646932 0.031879596 1.02E-05 4.990839469 -0.1110765 RLPQDHADS(ph)CVVSS(ph)DDEELSR ddPTM_HeLa_Curcumin_4h_R1 1 RLPQDHADSCVVSSDDEELSR 21 1 P78317;D6RA71 P78317 RNF4 E3 ubiquitin-protein ligase RNF4 2 0 RLPQDHADS(0.998)CVVS(0.32)S(0.68)DDEELS(0.001)R 92.147 0.00016832 21107000 2168.6 1961.8 2352.8 2248.7 2194.2 3076.3 1451.3 1580.4 2310.8 1631.9 TRUE FALSE FALSE 1996.953022 2131.36925 2439.996838 2239.395475 2168.035598 2438.240703 1492.019572 2062.256685 2057.311021 1688.608404 1.182602797 1.262204574 1.444974947 1.326178095 1.283918517 1.443934957 0.883579383 1.221275863 1.218347023 1 10.72161908 -8.297004576 0.876846825 1.024486209 1.263527007 0.080785417 0.160554927 0.483024313 0.783970006 0.053942299 0.033557281 5.05E-09 8.297004576 0.239040797 RLPS(ph)S(ph)PASPSPK ddPTM_HeLa_Curcumin_4h_R1 1 RLPSSPASPSPK 12 1 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 2 0 RLPS(0.993)S(0.957)PAS(0.025)PS(0.025)PK 101.72 0.012795 10298000 4119.2 2545 3044.4 3180.8 3619.3 3232.2 2313.1 3133.1 3705.4 3250.9 TRUE FALSE FALSE 3793.160973 2764.97846 3157.228142 3167.638692 3576.142211 2561.805286 2377.999361 4088.367767 3298.92689 3363.868533 1.127618674 0.821963888 0.93857061 0.941665425 1.063104035 0.761565222 0.706923989 1.215376798 0.980694358 1 11.71590561 -7.26736858 24.74235257 1.060264373 0.913820738 0.111451172 0.142665669 510.0544827 2128436.014 0.023374261 0.027102371 5.40E-08 7.26736858 -0.146443635 RLPSS(ph)PASPSPK ddPTM_HeLa_Curcumin_4h_R1 1 RLPSSPASPSPK 12 1 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 RLPS(0.416)S(0.583)PAS(0.001)PSPK 118.73 0.0058207 22928000 5563.6 4213.9 4379.8 4660.8 4497.8 4110.8 3259.2 3622.2 6007.2 3986.7 TRUE FALSE FALSE 5123.235189 4578.130739 4542.119241 4641.514845 4444.166673 3258.173742 3350.64438 4726.592105 5348.225189 4125.237528 1.241924896 1.109785972 1.101056414 1.125150931 1.077311704 0.789814821 0.812230655 1.145774534 1.296464786 1 12.01026148 -5.415865184 6.212458057 1.115560237 0.906597059 0.412325312 0.11927398 0.189220061 9.440889379 0.017282323 0.038931841 3.84E-06 5.415865184 -0.208963178 RLPTEEEWEFAAR ddPTM_HeLa_Curcumin_4h_R1 2 RLPTEEEWEFAAR 13 1 C9JL30;A8MXB9;H7C3B2;A0A494C1B1;J3KQJ1;C9J660;F8WA42;Q8NBJ7-2;Q8NBJ7;Q8NBJ7-3 C9JL30 SUMF2 Sulfatase-modifying factor 2 0 0 ; ; 122.52 0.0010995 3789800 4392.8 4757.6 5163.6 4809.2 4035.8 4067.5 3763.8 2369.57 4379.2 5016.3 FALSE FALSE TRUE 4045.105245 5168.825745 5354.967558 4789.300805 3987.675721 3223.85465 3869.402098 3092.040985 3898.812716 5190.616052 0.779311204 0.995801981 1.031663199 0.922684467 0.768247098 0.621092876 0.745461051 0.595698267 0.751127164 1 12.34169006 -5.582847863 3.329033 0.914632502 0.664832463 0.612525411 0.092986164 0.137068102 3.086384308 0.014937911 0.03244678 2.61E-06 5.582847863 -0.249800038 RLQSIGTENTEENRR ddPTM_HeLa_Curcumin_4h_R1 3 RLQSIGTENTEENRR 15 2 P04075;H3BQN4;J3KPS3;P04075-2;H3BPS8;H3BUH7;H3BR04;H3BMQ8 P04075 ALDOA Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase 0 0 ;; ;; 81.239 0.0063773 31943200 4303.26 4586.5 3971.11 3807.6 3384.7 4981.77 4178.74 3760.73 4970 5477 FALSE FALSE TRUE 3962.65243 4982.936623 4118.28283 3791.84516 3344.339663 3948.494746 4295.984198 4907.359265 4424.803434 5667.325342 0.699210331 0.879239557 0.726671328 0.669071375 0.590108995 0.696712207 0.758026748 0.865903926 0.780756912 1 12.46845231 -9.451766788 0.596983605 1.059518813 0.723625429 0.120871203 0.106484461 0.766983655 0.35151729 0.146771838 0.019411704 3.53E-10 9.451766788 -0.335893385 SSSSGDQSSDSLNS(ph)PTLLAL ddPTM_HeLa_Curcumin_4h_R1 1 SSSSGDQSSDSLNSPTLLAL 20 0 P15408;P15408-3;P15408-2 P15408 FOSL2 Fos-related antigen 2 1 0 SSSSGDQSSDSLNS(0.987)PT(0.013)LLAL 147.33 5.94E-05 4369100 1997.7 1643.3 1560.8 1753.2 1826.8 2488.8 1646.8 612.87 2247 1601.6 TRUE FALSE FALSE 1839.579937 1785.33953 1618.644621 1745.945723 1805.016603 1972.594825 1693.004776 799.7312417 2000.509722 1657.255481 1.110015902 1.077286846 0.976701927 1.053516337 1.089160135 1.190278052 1.021571384 0.482563643 1.207122103 1 10.69458031 -4.265270853 4.938629883 1.061004142 0.454491355 0.858975242 0.072469887 0.039205919 2.889427877 0.008748486 0.080788605 5.43E-05 4.265270853 -0.606512787 down RLS(ph)DCESTDVK ddPTM_HeLa_Curcumin_4h_R1 1 RLSDCESTDVK 11 1 Q7Z333-3;Q7Z333;Q7Z333-4 Q7Z333-3 SETX Probable helicase senataxin 1 0 RLS(1)DCESTDVK 147.1 0.00039919 15415000 3043.2 2492.5 2719.3 3051.6 3163.3 3476 3179 2358.6 3188.7 2679.7 TRUE FALSE FALSE 2802.327509 2707.940594 2820.07965 3038.973288 3125.579714 2755.038417 3268.194184 3077.726282 2838.907588 2772.819376 1.010641924 0.976601872 1.017044123 1.095986747 1.127220814 0.993587408 1.178653833 1.109962773 1.023834301 1 11.43713793 -6.287002764 4.158969676 1.002866782 1.101532618 0.539754042 0.044228337 0.120111597 4.883061716 0.006341769 0.010138596 5.16E-07 6.287002764 0.098665836 FNDEHIPES(ph)PYLVPVIAPSDDAR ddPTM_HeLa_Curcumin_4h_R1 1 FNDEHIPESPYLVPVIAPSDDAR 23 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3 O75369-8 FLNB Filamin-B 1 0 FNDEHIPES(0.91)PY(0.089)LVPVIAPSDDAR 52.898 0.0080602 2197800 478.35 282.26 374.99 471.22 376.04 539.02 692.03 1721.7 467.04 295.47 TRUE FALSE FALSE 440.4880927 306.6572967 388.8874593 469.2702165 371.5559686 427.221176 711.4464993 2246.638404 415.8068805 305.7375605 1.440739214 1.003008254 1.271964945 1.534879181 1.215277469 1.397346061 2.326984287 7.348257769 1.360012423 1 8.256149991 -4.216948325 2.34887177 1.233854347 9.260490832 0.990957161 0.1731425 0.050891585 0.299934794 0.029655966 0.867426264 6.07E-05 4.216948325 8.026636485 up RLS(ph)ESSALK ddPTM_HeLa_Curcumin_4h_R1 1 RLSESSALK 9 1 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 0 RLS(0.999)ES(0.001)SALK 116.74 0.0033185 15872000 5617.1 5374.7 5666.3 5776.6 7684.2 7702.5 8181.9 6531.9 6533 5659.5 TRUE FALSE FALSE 5172.500608 5839.265119 5876.298063 5752.69796 7592.570934 6104.914675 8411.462094 8523.446241 5816.346245 5856.167204 0.883256988 0.997113797 1.003437549 0.982331576 1.296508564 1.042476156 1.436342543 1.455464973 0.993200167 1 12.51574103 -4.626317411 0.603427744 0.944888643 1.700604445 0.763276645 0.095185042 0.767521088 0.246545271 0.017236009 0.368122565 2.36E-05 4.626317411 0.755715801 RLS(ph)GS(ph)S(ph)EDEEDSGKGEPTAK ddPTM_HeLa_Curcumin_4h_R1 1 RLSGSSEDEEDSGKGEPTAK 20 2 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 3 0 RLS(0.971)GS(0.978)S(0.997)EDEEDS(0.049)GKGEPT(0.005)AK 70.235 0.0052011 12804000 12742 11060 11164 12546 11090 13931 11640 9863.7 13626 12843 TRUE FALSE FALSE 11733.45725 12015.97712 11577.74766 12494.08798 10957.75899 11041.55357 11966.58707 12871.09672 12131.26189 13289.29329 0.8829256 0.904184809 0.871208679 0.940161956 0.824555434 0.830860853 0.90046828 0.968531316 0.91285982 1 13.69797677 -9.23654956 0.655704874 1.012997128 0.886011111 0.125065713 0.049457911 0.653055512 0.427108088 0.04792533 0.009169679 5.80E-10 9.23654956 -0.126986017 RLS(ph)LGAQK ddPTM_HeLa_Curcumin_4h_R1 1 RLSLGAQK 8 1 Q9H788-2;Q9H788 Q9H788-2 SH2D4A SH2 domain-containing protein 4A 1 0 RLS(1)LGAQK 74.533 0.018003 44763000 4161.5 1635.7 3092.8 3467.1 4280.3 9188.1 7296.4 2425.9 4495.9 3460.2 TRUE FALSE FALSE 3832.112884 1777.082619 3207.421889 3452.754059 4229.260218 7282.384489 7501.117347 3165.545743 4002.711018 3580.441692 1.070290543 0.496330557 0.895817378 0.964337463 1.181211868 2.033934669 2.095025695 0.884121573 1.117937775 1 11.80592186 -5.445623506 5.057382803 0.976371648 1.709399715 0.475595201 0.347038077 0.138365299 6.324510321 0.047320887 0.107014725 3.58E-06 5.445623506 0.733028066 RLS(ph)LGQGDSTEAATEER ddPTM_HeLa_Curcumin_4h_R1 3 RLSLGQGDSTEAATEER 17 1 J3KPS2;A0A494C1T9;Q6ZRV2 J3KPS2 FAM83H Protein FAM83H 1 0 RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER;RLS(1)LGQGDSTEAATEER ;; 109.32 0.00057362 61950400 3776.17 3269.49 4028.84 4450.09 3983.1 4697.2 3315.52 1849.54 4022 3252.49 TRUE FALSE FALSE 3477.28216 3552.090147 4178.152355 4431.676707 3935.604134 3722.947772 3408.544568 2413.456232 3580.796663 3365.513785 1.033209899 1.055437705 1.241460479 1.316790538 1.169391773 1.10620488 1.012785799 0.717113756 1.063967314 1 11.71661105 -4.273575275 3.236769136 1.072151862 0.671596673 0.548894082 0.103129898 0.244242127 4.084032593 0.017551357 0.240979645 5.33E-05 4.273575275 -0.400555189 RLS(ph)LPADIR ddPTM_HeLa_Curcumin_4h_R1 2 RLSLPADIR 9 1 H0YBX5;E5RJM2;E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RIY8;E5RIU4;Q00537-2;Q00537;F8VZY6;F8VQZ9;F5H6Z0 H0YBX5;Q00537-2 CDK16;CDK17 Cyclin-dependent kinase 16;Cyclin-dependent kinase 17 1 0 RLS(1)LPADIR;RLS(1)LPADIR ; 96.23 0.00719 79976300 9778.8 8939.9 9794.6 9584.6 10797.5 13733.3 11209.7 5128.5 9551.5 8320.6 TRUE FALSE FALSE 9004.797661 9712.625121 10157.59649 9544.941465 10668.74686 10884.85877 11524.21401 6692.156041 8503.724347 8609.740231 1.045884942 1.128097348 1.17977967 1.108621307 1.23914852 1.264249383 1.33850891 0.777277347 0.987686518 1 13.07175399 -7.26526477 1.435712381 1.015551193 1.169338076 0.159248446 0.141951226 0.460581819 1.813538516 0.025901132 0.030692989 5.43E-08 7.26526477 0.153786882 RLS(ph)LPGLLS(ph)QVSPR ddPTM_HeLa_Curcumin_4h_R1 1 RLSLPGLLSQVSPR 14 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 2 0 RLS(1)LPGLLS(0.606)QVS(0.394)PR 60.669 0.019979 10750000 2094.3 1546.7 1562 1921.3 2069.4 2037.3 1503.6 698.37 2185.4 1649 TRUE FALSE FALSE 1928.533945 1680.389856 1619.889094 1913.35017 2044.723757 1614.741015 1545.786969 911.2997981 1945.667088 1706.302627 1.130241444 0.984813496 0.949356268 1.121342802 1.198335936 0.946339172 0.905927791 0.534078647 1.140282536 1 10.73665783 -4.160601 1.492534695 1.059411174 0.236019535 0.801077482 0.079972643 0.490308873 0.822936971 0.012056988 0.636406724 6.91E-05 4.160601 -0.823391639 RLS(ph)LTLR ddPTM_HeLa_Curcumin_4h_R1 2 RLSLTLR 7 1 Q00537-2;Q00537;F8VZY6;F8VQZ9;F8VUX2;F8W1S5 Q00537-2 CDK17 Cyclin-dependent kinase 17 1 0 RLS(0.974)LT(0.026)LR;RLS(0.974)LT(0.026)LR ; 75.652 0.017687 26709000 3381.4 2342.2 3265.4 3163.4 2872.5 4658.9 3913.2 2340.6 3526 3226.8 TRUE FALSE FALSE 3113.758622 2544.649331 3386.418597 3150.310689 2838.247314 3692.591623 4022.99386 3054.238165 3139.206622 3338.93106 0.932561519 0.762114966 1.014222377 0.943508756 0.850046695 1.105920295 1.20487479 0.914735318 0.94018312 1 11.70517059 -5.23899552 24.20762481 0.946454456 1.088146633 0.321732035 0.097462302 506.0701411 545838.2184 0.013403808 0.034140851 5.77E-06 5.23899552 0.141692177 QDS(ph)LSSEVDTLK ddPTM_HeLa_Curcumin_4h_R1 1 QDSLSSEVDTLK 12 0 Q08378;Q08378-2;Q08378-4 Q08378 GOLGA3 Golgin subfamily A member 3 1 0 QDS(0.981)LS(0.016)S(0.003)EVDTLK 118.2 0.0037494 2944000 1068.7 767.6 1093.3 1221.7 840.05 1562 1545.6 3984.2 973.94 965.15 TRUE FALSE FALSE 984.1112673 833.9479236 1133.81866 1216.644929 830.0329524 1238.023593 1588.965376 5198.964239 867.1012187 998.6888907 0.985403239 0.835042756 1.135307172 1.218242178 0.831122645 1.239648908 1.591051419 5.205789598 0.868239576 1 9.963891513 -4.216580112 2.572440045 1.009804485 6.384726312 0.9870625 0.14308154 0.041708342 0.315241467 0.018778584 0.506743876 6.07E-05 4.216580112 5.374921828 up RLS(ph)PPACTLR ddPTM_HeLa_Curcumin_4h_R1 1 RLSPPACTLR 10 1 P28360 P28360 MSX1 Homeobox protein MSX-1 1 0 RLS(1)PPACTLR 95.523 0.0072872 5967800 1220.6 958.6 952.9 1217.2 1091.4 1244.5 1060 981.93 1561.1 1146.1 TRUE FALSE FALSE 1123.988222 1041.457113 988.2153123 1212.163549 1078.385768 986.3766716 1089.740747 1281.315937 1389.851236 1185.92689 0.947771934 0.878179862 0.833285189 1.022123336 0.909318928 0.831734806 0.9188937 1.080434172 1.171953556 1 10.21179936 -8.230594172 1.116486258 0.990233649 0.922141773 0.197763126 0.093294527 0.637943891 1.645183254 0.020722229 0.014924674 5.88E-09 8.230594172 -0.068091875 VSSPLSPLS(ph)PGIK ddPTM_HeLa_Curcumin_4h_R1 2 VSSPLSPLSPGIK 13 0 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 0 VSSPLS(0.001)PLS(0.999)PGIK;VSS(0.002)PLS(0.012)PLS(0.986)PGIK ; 158.52 0.00030872 55112000 3858.3 3229.2 3252.6 3661.3 3123.5 5303.7 5051.1 10696.7 3861.5 3814.8 TRUE FALSE FALSE 3552.911484 3508.317659 3373.144217 3646.150511 3086.254303 4203.652835 5192.820272 13958.07459 3437.903111 3947.364016 0.900071914 0.888774799 0.854530822 0.923692493 0.781851962 1.064926573 1.315515937 3.536049508 0.870936427 1 11.94667385 -4.216382876 2.517804148 0.932003156 4.288211585 0.990249788 0.077703405 0.043391938 0.308836992 0.011774634 0.324514221 6.08E-05 4.216382876 3.356208429 up RLS(ph)QSDEDVIR ddPTM_HeLa_Curcumin_4h_R1 2 RLSQSDEDVIR 11 1 H0Y917;A0A499FIZ0;Q9H7D7-3;Q9H7D7-4;Q9H7D7-2;Q9H7D7 H0Y917 WDR26 WD repeat-containing protein 26 1 0 RLS(0.948)QS(0.052)DEDVIR;RLS(0.995)QS(0.005)DEDVIR ; 139.64 0.00066029 173951000 5753 4789.3 5338.3 5111.5 5292.7 6482.6 4896.5 4643.3 5208.6 4929.8 TRUE FALSE FALSE 5297.643979 5203.265751 5536.142094 5090.349967 5229.588009 5138.035686 5033.882612 6059.020795 4637.229611 5101.110183 1.038527652 1.020026144 1.08528181 0.997890613 1.025186248 1.007238719 0.986820992 1.187784733 0.909062821 1 12.31659555 RLS(ph)RAT(ph)RK ddPTM_HeLa_Curcumin_4h_R1 1 RLSRATRK 8 3 P47900 P47900 P2RY1 P2Y purinoceptor 1 2 0 RLS(1)RAT(1)RK 62.659 0.0078021 0 841.42 909.44 804.52 1001.3 902.3 1069.6 867.78 973.46 1180.2 1109.4 TRUE FALSE FALSE 774.8207191 988.0479412 834.3362189 997.1568859 891.5406618 847.7529031 892.1275713 1270.263473 1050.735013 1147.951567 0.674959416 0.86070525 0.726804373 0.868640206 0.776636129 0.738491873 0.777147396 1.106547967 0.915313017 1 10.16484606 -9.578278224 1.372963184 0.999584619 0.793081854 0.158274387 0.116659541 0.415874526 1.410080648 0.078609372 0.018520819 2.64E-10 9.578278224 -0.206502765 AVS(ph)PLDPSKEVSGK ddPTM_HeLa_Curcumin_4h_R1 2 AVSPLDPSKEVSGK 14 1 Q14865-2;Q14865 Q14865-2 ARID5B AT-rich interactive domain-containing protein 5B 1 0 AVS(0.978)PLDPS(0.02)KEVS(0.001)GK;AVS(0.993)PLDPS(0.007)KEVSGK ; 123.76 0.014103 22300600 8583.7 5881.36 7547.28 7527.58 7864.93 9946 6232.29 1125.46 8003.43 7173.77 TRUE FALSE FALSE 7904.291088 6389.718552 7826.988836 7496.432869 7771.145847 7883.087485 6407.151284 1468.607573 7125.473753 7423.057974 1.064829497 0.860793298 1.054415696 1.009884726 1.046892787 1.061973046 0.863141755 0.197844012 0.959910832 1 12.85779792 -4.265013377 2.770304458 1.021852837 0.046567605 0.941271928 0.06029201 0.064149385 0.666894608 0.007920458 0.141171567 5.43E-05 4.265013377 -0.975285232 down RLS(ph)SASTGKPPLSVEDDFEK ddPTM_HeLa_Curcumin_4h_R1 1 RLSSASTGKPPLSVEDDFEK 20 2 O75152;A0A1B0GTU1;A0A494C0C4 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 0 RLS(0.484)S(0.484)AS(0.024)T(0.008)GKPPLSVEDDFEK 77.554 0.00096621 33973000 1769.1 1621.5 1739.4 1938.9 1821.8 2304.8 3162.9 3100.3 2123.9 1925 TRUE FALSE FALSE 1629.073868 1761.655235 1803.863694 1930.877346 1800.076225 1826.7585 3251.642461 4045.567198 1890.913484 1991.893607 0.817851848 0.884412314 0.905602432 0.969367711 0.90370099 0.917096422 1.632437822 2.031015705 0.94930446 1 10.95992488 -4.62359098 2.773598533 0.910237399 1.998870037 0.977631895 0.056673175 0.03550334 0.511016499 0.010822997 0.06054406 2.38E-05 4.62359098 1.088632639 RLS(ph)SSSATLLNSPDR ddPTM_HeLa_Curcumin_4h_R1 1 RLSSSSATLLNSPDR 15 1 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;A0A087WZ40 Q14244-3 MAP7 Ensconsin 1 0 RLS(0.867)S(0.095)S(0.018)S(0.018)AT(0.002)LLNSPDR 91.592 0.01078 9310200 1678.8 1441.2 1418.6 1352.6 1509.8 1980.8 1436.1 918.41 1680 1367.8 TRUE FALSE FALSE 1545.921209 1565.770906 1471.174564 1347.0033 1491.796621 1569.959752 1476.393101 1198.428981 1495.708203 1415.330948 1.092268356 1.106293131 1.039456225 0.9517232 1.054026709 1.109252754 1.043143374 0.846748234 1.056790431 1 10.46692372 -6.50563843 23.93882089 1.050606171 1.010614253 0.132704503 0.071013078 1051.195336 1459624.783 0.011673023 0.017579118 3.12E-07 6.50563843 -0.039991918 RLS(ph)SSTVAISYS(ph)PDR ddPTM_HeLa_Curcumin_4h_R1 1 RLSSSTVAISYSPDR 15 1 Q96T17;Q96T17-2;Q96T17-5 Q96T17 MAP7D2 MAP7 domain-containing protein 2 2 0 RLS(0.986)S(0.013)STVAIS(0.005)YS(0.995)PDR 117.2 0.001578 0 2049.4 2381.4 2139.1 2141 2893 2954.8 2221.6 1356 2866.3 2182.8 TRUE FALSE FALSE 1887.187827 2587.237605 2218.376928 2132.141109 2858.502864 2341.941173 2283.932117 1769.438158 2551.874061 2258.652138 0.835537176 1.145478563 0.982168476 0.943988264 1.265579067 1.036875548 1.011192507 0.78340446 1.12982164 1 11.14124638 -7.271545835 24.91047975 0.922337003 1.028687099 0 0.140088633 1034.852538 2550708.836 0.022059848 0.02537815 5.35E-08 7.271545835 0.106350096 RLS(ph)SSTVAISYSPDR ddPTM_HeLa_Curcumin_4h_R1 1 RLSSSTVAISYSPDR 15 1 Q96T17;Q96T17-2;Q96T17-5 Q96T17 MAP7D2 MAP7 domain-containing protein 2 1 0 RLS(0.65)S(0.19)S(0.056)T(0.104)VAISYSPDR 103.77 0.0012501 0 867.01 572.3 655.66 601.71 754.11 919.96 723.96 845.06 814.69 725.8 TRUE FALSE FALSE 798.3852436 621.7670619 679.9593364 599.2202835 745.1177308 729.1499259 744.2723692 1102.714904 725.3205453 751.021496 1.063065768 0.82789516 0.905379327 0.797873678 0.99213902 0.970877571 0.991013404 1.46828674 0.965778675 1 9.552710391 -4.261481751 7.205494888 0.984532931 1.474602852 0.761685193 0.085232112 0.046578204 20.15694288 0.013661198 0.110560551 5.48E-05 4.261481751 0.490069921 RLS(ph)TIFEECDEELER ddPTM_HeLa_Curcumin_4h_R1 1 RLSTIFEECDEELER 15 1 Q5T5P2;Q5T5P2-3;A0A0U1RRK8 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 0 RLS(0.933)T(0.067)IFEECDEELER 99.747 0.0063769 5458200 1154 1188.1 1082 1048.5 1055.7 1756.7 1495 483.66 1476.3 1079.4 TRUE FALSE FALSE 1062.659682 1290.79407 1122.099872 1044.161585 1043.111467 1392.340618 1536.945676 631.1257075 1314.353584 1116.90907 0.951429003 1.155684115 1.004647471 0.934867138 0.933926938 1.246601586 1.376070549 0.565064538 1.176777608 1 10.12529602 -5.319417265 24.99869514 0.986698034 1.093930525 0 0.21319277 598.1726333 257916.9813 0.026770463 0.059860587 4.79E-06 5.319417265 0.107232491 RLS(ph)VLEEEATEGGTSR ddPTM_HeLa_Curcumin_4h_R1 1 RLSVLEEEATEGGTSR 16 1 A0A1B0GVE3;O75808-2;O75808 A0A1B0GVE3 CAPN15 Calpain-15 1 0 RLS(1)VLEEEATEGGTSR 112.82 0.0006628 4690500 763.52 518.62 440.45 595.18 721.65 772.03 822.32 289.69 653.37 741.84 TRUE FALSE FALSE 703.0865863 563.4472019 456.7734645 592.7173029 713.0447951 611.9022754 845.392086 378.0151474 581.6969457 767.6188848 0.915931851 0.734019463 0.595052406 0.772150496 0.928904707 0.797143332 1.101317467 0.492451599 0.757793949 1 9.584246395 -7.469317 3.316623419 0.965804757 0.787355982 0.040364201 0.170648758 0.275469118 5.827406438 0.027321899 0.030236425 3.39E-08 7.469317 -0.178448775 RLS(ph)YNTASNK ddPTM_HeLa_Curcumin_4h_R1 1 RLSYNTASNK 10 1 P49207 P49207 RPL34 60S ribosomal protein L34 1 0 RLS(0.787)YNT(0.213)ASNK 122.66 0.0019242 23454000 3339.8 3078.3 1684.3 2380.9 2398.9 3298.1 3243.8 3819.4 3741.5 2278.8 TRUE FALSE FALSE 3075.451306 3344.374535 1746.72164 2371.048467 2370.294684 2614.036883 3334.812298 4983.917478 3331.066811 2357.98813 1.304269206 1.418316951 0.740767783 1.005538763 1.005219091 1.108587804 1.414261698 2.113631283 1.412673273 1 11.20334074 -4.297057965 2.204936615 1.11551584 2.328714116 0.693558646 0.198979406 0.242927969 1.416086788 0.02781612 0.557001797 5.05E-05 4.297057965 1.213198276 RLSGS(ph)SEDEEDS(ph)GKGEPTAK ddPTM_HeLa_Curcumin_4h_R1 1 RLSGSSEDEEDSGKGEPTAK 20 2 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 2 0 RLS(0.047)GS(0.63)S(0.328)EDEEDS(0.668)GKGEPT(0.327)AK 67.532 0.005562 5341400 1919.6 1314 1556.8 1651.6 1716.8 2177.2 1814.3 1779.3 1790.2 1842.1 TRUE FALSE FALSE 1767.661634 1427.576305 1614.496378 1644.766117 1696.328281 1725.624178 1865.204375 2321.800379 1593.819539 1906.112838 0.927364634 0.748946377 0.847009865 0.862890215 0.889941166 0.905310611 0.978538279 1.218081287 0.836162218 1 10.89641781 -4.270479916 2.974390725 0.925209503 1.263567007 0.610661599 0.075060657 0.238859599 3.084937838 0.01208346 0.189533058 5.36E-05 4.270479916 0.338357504 RLSLPGLLSQVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 RLSLPGLLSQVSPR 14 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 0 RLSLPGLLSQVS(1)PR;RLSLPGLLSQVS(1)PR ; 138.28 0.00038475 17606100 3599.8 2692.7 3133.1 3063.6 3219.8 3587.7 2885.9 2076.43 3362.7 3531.7 TRUE FALSE FALSE 3314.872032 2925.44499 3249.215442 3050.923635 3181.405988 2843.570578 2966.870587 2709.523948 2993.820223 3654.426312 0.907084108 0.800520996 0.889117789 0.834857068 0.870562358 0.778116819 0.811856728 0.741436197 0.819231247 1 11.83542923 -4.253641691 0.04127355 1.554404916 6.22E-13 0.099323956 0.066785054 77.70124683 0.508907147 7.079462711 12.73834705 5.58E-05 4.253641691 -1.554404916 SVSS(ph)PTSSNTPT(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 2 SVSSPTSSNTPTPTK 15 0 Q5M775-4;Q5M775;Q5M775-5;Q5M775-3;Q5M775-2 Q5M775-4 SPECC1 Cytospin-B 2 0 S(0.006)VS(0.032)S(0.931)PT(0.323)S(0.045)S(0.075)NT(0.044)PT(0.544)PT(0.001)K;S(0.022)VS(0.112)S(0.861)PT(0.111)S(0.016)S(0.035)NT(0.021)PT(0.699)PT(0.122)K ; 117.13 0.0026627 7503200 6882.5 5908 5778.3 6297.3 6130.3 9619.4 5678 1717.8 7452.7 5113.7 TRUE FALSE FALSE 6337.742863 6418.661194 5992.448881 6271.243441 6057.200176 7624.228007 5837.309398 2241.549312 6635.157456 5291.400694 1.197743892 1.213036314 1.132488206 1.185176441 1.144725287 1.440871415 1.103169035 0.423621162 1.25395105 1 12.36943396 -4.264967989 5.766648558 1.139732395 0.402618098 0.789809799 0.115905204 0.051650119 7.442352712 0.017818382 0.149264769 5.43E-05 4.264967989 -0.737114297 down RLSSSTVAISYS(ph)PDR ddPTM_HeLa_Curcumin_4h_R1 1 RLSSSTVAISYSPDR 15 1 Q96T17;Q96T17-2;Q96T17-5 Q96T17 MAP7D2 MAP7 domain-containing protein 2 1 0 RLSSSTVAISYS(1)PDR 112.03 0.0031747 9074800 1222.6 967.87 1111.5 1084.2 1028.7 1289.2 804.71 599.16 1335.3 895.05 TRUE FALSE FALSE 1125.82992 1051.52837 1152.693168 1079.713868 1016.433424 1021.805388 827.2879968 781.8411258 1188.820931 926.1529209 1.215598304 1.135372298 1.244603501 1.165805175 1.097479046 1.103279345 0.893252052 0.844181461 1.283611922 1 9.855106612 -4.735121389 3.497683936 1.121869305 0.852527982 0.64677752 0.082297343 0.127945943 3.198141674 0.012937927 0.053475011 1.84E-05 4.735121389 -0.269341323 RLT(ph)VNEAVK ddPTM_HeLa_Curcumin_4h_R1 1 RLTVNEAVK 9 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 RLT(1)VNEAVK 129.74 0.0020726 11993000 2899.8 2701.6 3117.5 3224.6 3463.6 3616.4 3269.6 3333.2 3170.1 3147.1 TRUE FALSE FALSE 2670.27777 2935.114266 3233.037292 3211.25746 3422.298832 2866.317875 3361.336176 4349.477336 2822.347961 3256.461491 0.819993658 0.901320121 0.992806855 0.986118666 1.050925626 0.880194003 1.032205105 1.335645254 0.866691643 1 11.66908945 -4.291806202 2.657609592 0.930763409 1.402040905 0.753303977 0.06828274 0.189064174 1.821211746 0.011770061 0.190151772 5.11E-05 4.291806202 0.471277496 RLTDLDK(ac)AQLLEIAK ddPTM_HeLa_Curcumin_4h_R1 1 RLTDLDKAQLLEIAK 15 2 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2;H7C2G8 P18583-10 SON Protein SON 0 1 RLTDLDK(1)AQLLEIAK 125.39 0.00027009 1065300 585.61 538.7 547.63 598.11 602.14 976.21 813.42 694.2 806.6 582.18 FALSE TRUE FALSE 539.2583506 585.2628276 567.9256495 595.6351793 594.9598738 773.7330418 836.242376 905.8583843 718.117998 602.4107117 0.895167267 0.971534563 0.942754899 0.988752636 0.987631631 1.284394561 1.388159871 1.503722239 1.192073753 1 9.234603613 -5.063611154 1.585261467 0.950636815 1.48355146 0.826352131 0.083790751 0.058124313 0.266809897 0.006526841 0.029544112 8.64E-06 5.063611154 0.532914644 RLTLEDLEDSWDR ddPTM_HeLa_Curcumin_4h_R1 2 RLTLEDLEDSWDR 13 1 Q6P2Q9;I3L3Z8 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 0 ; ; 195.87 5.56E-06 38678000 4513.6 3870.5 3782.3 3930 3656.4 4537.1 4462.5 3181.4 4914.7 4224.5 FALSE FALSE TRUE 4156.343797 4205.048773 3922.475365 3913.738701 3612.799818 3596.054316 4587.70574 4151.394215 4375.569706 4371.301061 0.950825335 0.961967322 0.89732446 0.895325819 0.826481582 0.8226508 1.049505782 0.949693045 1.000976516 1 12.09384703 -7.59274652 0.835079092 0.988214649 0.907660801 0.240946576 0.061773607 0.625188407 0.919318043 0.017578679 0.017149239 2.55E-08 7.59274652 -0.080553848 RLTVSSLQESGLK ddPTM_HeLa_Curcumin_4h_R1 1 RLTVSSLQESGLK 13 1 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 107.93 0.00078217 4166000 4246.3 3800.2 3649 3603.5 4541.8 4731.6 3856.9 4387.6 3461 3232.5 FALSE FALSE TRUE 3910.200874 4128.672355 3784.23515 3588.589672 4487.642001 3750.212824 3965.114234 5725.359042 3081.336959 3344.829134 1.169028586 1.234344772 1.131368748 1.072876828 1.341665544 1.121197129 1.185445975 1.711704488 0.921224025 1 11.7077168 -1.775724131 1.132750394 1.110397418 199.9983823 0.709109821 0.111556863 202.0943047 1.005861281 0.01620335 103549.9575 0.016760072 1.775724131 198.8879849 RMDSVTWQEGK ddPTM_HeLa_Curcumin_4h_R1 1 RMDSVTWQEGK 11 1 A0A140T8Z4;A0A0G2JK05;Q5SQ64;Q5SQ64-2 A0A140T8Z4 LY6G6F Lymphocyte antigen 6 complex locus protein G6f 0 0 78.149 0.016704 12809000 1428.5 1182.6 1419.4 1144.1 1640.5 1792.7 1448.6 1101.9 1406.7 1121.8 FALSE FALSE TRUE 1315.432718 1284.818674 1472.004213 1139.366017 1620.938109 1420.873812 1489.243817 1437.864237 1252.388529 1160.782467 1.133229314 1.106855687 1.268113755 0.981549989 1.396418498 1.224065536 1.282965465 1.238702581 1.078917511 1 10.18088192 -7.08027227 0.154708186 0.886466046 1.411881656 0.390574973 0.098540096 2.797705693 0.357180766 0.490815908 0.593009546 8.31E-08 7.08027227 0.52541561 RMEDEGGFPVPQENGQPES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 5 RMEDEGGFPVPQENGQPESPR 21 1 J3KPS2;A0A494C1T9;Q6ZRV2 J3KPS2 FAM83H Protein FAM83H 1 0 RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR;RMEDEGGFPVPQENGQPES(1)PR ;;;; 149.94 4.41E-06 52388100 7831.8 6853.57 5879.24 7089.92 6997 10018.2 7846.9 2743.85 8148.4 6411.79 TRUE FALSE FALSE 7211.904766 7445.962052 6097.129806 7060.58379 6913.565345 7940.312392 8067.062895 3580.437234 7254.540906 6634.599225 1.08701438 1.122292666 0.918989919 1.064206526 1.04204717 1.196803623 1.215908094 0.539661419 1.093440713 1 12.6957936 -4.250615183 24.83652674 1.059855712 0.539661095 0.781955244 0.085224981 537.2709114 1232762.937 0.012188886 0.239481173 5.62E-05 4.250615183 -0.520194617 RMEELHNQEVQK ddPTM_HeLa_Curcumin_4h_R1 4 RMEELHNQEVQK 12 1 Q15233;Q15233-2;H7C367;C9JYS8 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 0 ;;; ;;; 86.911 0.0045843 16276700 8130.9 6207.4 6696.23 7532.1 7574.7 8556.8 7436.1 5869 7879.3 7560.59 FALSE FALSE TRUE 7487.330685 6743.939996 6944.398174 7500.934166 7484.37665 6782.023225 7644.736953 7658.431082 7014.960503 7823.31994 0.957052855 0.862030448 0.887653608 0.958791692 0.956675262 0.86689836 0.977172992 0.978923416 0.896673095 1 12.93356525 -7.976125715 1.540688464 0.988402349 0.927860516 0 0.050670106 0.330078558 1.614451355 0.009797213 0.008598154 1.06E-08 7.976125715 -0.060541833 RMEFT(ph)SS(ph)CPNVSERS(ph)FDNVRS(ph)LK ddPTM_HeLa_Curcumin_4h_R1 1 RMEFTSSCPNVSERSFDNVRSLK 23 3 J3QRT1;P05813-2;P05813 J3QRT1 CRYBA1 "Beta-crystallin A3;Beta-crystallin A3, isoform A1, Delta4 form;Beta-crystallin A3, isoform A1, Delta7 form;Beta-crystallin A3, isoform A1, Delta8 form" 4 0 RMEFT(0.586)S(0.586)S(0.827)CPNVS(0.296)ERS(0.707)FDNVRS(0.998)LK 40.158 0.0090727 0 700.56 623.12 519.22 564.54 513.77 690.43 516.22 482.41 584.68 422.04 TRUE FALSE FALSE 645.1099368 676.9797162 538.46275 562.2040831 507.6436283 547.2270353 530.7037439 629.4945883 520.5420668 436.7058586 1.477218416 1.550196094 1.233010136 1.287374721 1.162438329 1.253079217 1.215243014 1.441461285 1.191974086 1 8.770518075 -9.4769051 1.246302256 1.001904826 1.335165124 0.296113436 0.131349553 0.321759392 0.902200521 0.089902216 0.022587801 3.33E-10 9.4769051 0.333260298 RMGSPEERR ddPTM_HeLa_Curcumin_4h_R1 1 RMGSPEERR 9 2 Q15042-4;Q15042;Q15042-3 Q15042-4 RAB3GAP1 Rab3 GTPase-activating protein catalytic subunit 0 0 118.5 0.016246 23366000 4225.1 3672.2 3903.7 4209.6 3693.1 4674.4 3729.4 3271.4 4501.6 3952.2 FALSE FALSE TRUE 3890.678877 3989.608605 4048.374556 4192.181791 3649.062195 3704.876749 3834.036927 4268.8348 4007.785742 4089.538656 0.951373542 0.975564468 0.989934293 1.025098952 0.892291894 0.905940024 0.937523092 1.043842634 0.980009258 1 11.99772239 -5.765622543 24.99990271 0.980458656 0.941589722 0.184193359 0.041842427 153.0409591 914629.6929 0.006375424 0.011856954 1.72E-06 5.765622543 -0.038868934 RMNS(ph)TGGQTPR ddPTM_HeLa_Curcumin_4h_R1 4 RMNSTGGQTPR 11 1 Q96ST2-3;Q96ST2;Q96ST2-2;A0A1B0GW95 Q96ST2-3 IWS1 Protein IWS1 homolog 1 0 RMNS(0.989)T(0.011)GGQTPR;RMNS(0.884)T(0.116)GGQTPR;RMNS(0.825)T(0.175)GGQTPR;RMNS(0.855)T(0.145)GGQTPR ;;; 123.95 0.0017273 31186900 2693.01 2148.64 2405.51 2098.5 1950.71 2702.34 2308.86 3669.46 2647.01 2550.09 TRUE FALSE FALSE 2479.855417 2334.358867 2494.660317 2089.816963 1927.449057 2141.844222 2373.640398 4788.261462 2356.639625 2638.705438 0.939800018 0.88466065 0.945410686 0.791985696 0.730452528 0.81170266 0.899547317 1.81462523 0.893104472 1 11.36561459 -4.260591301 24.82370999 0.921198177 1.814625539 0.911796525 0.086489338 16.58116558 485247.25 0.014683455 0.118931599 5.49E-05 4.260591301 0.893427361 RMNSTGGQT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 RMNSTGGQTPR 11 1 Q96ST2-3;Q96ST2;Q96ST2-2;A0A1B0GW95 Q96ST2-3 IWS1 Protein IWS1 homolog 1 0 RMNST(0.001)GGQT(0.999)PR 72.681 0.019236 2341900 486.99 667.97 390.92 579.86 469.66 970.49 476.5 158.19 628.68 434.25 TRUE FALSE FALSE 448.4442276 725.7063504 405.4078391 577.460693 464.0596112 769.1994343 489.8693076 206.4214028 559.7153769 449.3401552 0.998006126 1.61504896 0.902229268 1.285130399 1.032757936 1.711842188 1.090197041 0.459387839 1.245638455 1 8.811664184 RMS(ph)ADMSEIEAR ddPTM_HeLa_Curcumin_4h_R1 5 RMSADMSEIEAR 12 1 Q9UG54;O43318-4;O43318-3;O43318-2;O43318 Q9UG54 DKFZp586F0420;MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1 0 RMS(1)ADMSEIEAR;RMS(0.993)ADMS(0.007)EIEAR;RMS(1)ADMSEIEAR;RMS(1)ADMSEIEAR;RMS(0.998)ADMS(0.002)EIEAR ;;;; 177.63 0.00020158 90915400 9658.7 7301.02 8064.1 8160.4 8128.4 9210.1 6709.63 3779.5 9013.1 8095.42 TRUE FALSE FALSE 8894.203703 7932.087636 8362.96264 8126.634427 8031.474139 7299.821441 6897.88416 4931.852151 8024.38548 8376.735242 1.06177448 0.946918747 0.998355851 0.970143402 0.958783333 0.871439914 0.823457345 0.588755883 0.957937102 1 13.03217236 -3.710388527 0.623223337 1.022472138 3.42E-16 0.911785652 0.03758929 1.01577184 0.167598758 0.006309494 0.86889114 0.00019481 3.710388527 -1.022472138 SMS(ph)IDDTPR ddPTM_HeLa_Curcumin_4h_R1 1 SMSIDDTPR 9 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7;A0A0C4DGY6;A0A1B0GVW2 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 S(0.013)MS(0.986)IDDT(0.001)PR 94.363 0.016435 16914000 1747.7 1346 1859 1733.6 1680.7 2223.6 2375.3 3850.9 1916.5 1691.7 TRUE FALSE FALSE 1609.367701 1462.342242 1927.896175 1726.426823 1660.65875 1762.400295 2441.944525 5025.021683 1706.264745 1750.486449 0.919383124 0.835391924 1.101348814 0.986255463 0.948684151 1.00680602 1.3950091 2.870643006 0.974737477 1 10.77354018 -4.214926664 2.088811598 0.963392864 3.554512784 0.987142415 0.065012487 0.062032512 0.266365462 0.009594001 0.314766843 6.10E-05 4.214926664 2.591119919 up RMS(ph)VDYNGEQK ddPTM_HeLa_Curcumin_4h_R1 1 RMSVDYNGEQK 11 1 H3BUD4;A0A0A0MT40;Q15111-2;Q15111 H3BUD4 PLCL1 Phosphoinositide phospholipase C;Inactive phospholipase C-like protein 1 1 0 RMS(1)VDYNGEQK 59.418 0.0093243 0 3253.4 2761.5 2972.4 3178.7 2942.3 3307.9 2596.2 1953.8 3511.9 3032.2 TRUE FALSE FALSE 2995.889957 3000.191755 3082.559759 3165.547382 2907.214994 2621.804252 2669.042385 2549.504626 3126.653356 3137.568724 0.95484441 0.956215471 0.982467646 1.008917305 0.926582093 0.835616518 0.850672167 0.812573317 0.996521074 1 11.61543134 -5.397998254 2.970646538 0.97844837 0.833144334 0.922413841 0.019408789 0.059092651 0.992457402 0.003286977 0.008086638 4.00E-06 5.397998254 -0.145304036 EESREPAPAS(ph)PAPAGVEIR ddPTM_HeLa_Curcumin_4h_R1 3 EESREPAPASPAPAGVEIR 19 1 Q14195-2 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 1 0 EES(0.061)REPAPAS(0.939)PAPAGVEIR;EES(0.014)REPAPAS(0.986)PAPAGVEIR;EES(0.003)REPAPAS(0.997)PAPAGVEIR ;; 100.81 0.00041132 1841446000 7590.6 6609.8 6395.1 6804.9 6660.7 10090.9 9386.1 10511.6 7738 6547.4 TRUE FALSE FALSE 6989.796 7181.121659 6632.108032 6776.743127 6581.275503 7997.933592 9649.448705 13716.53845 6889.16076 6774.921663 1.031716136 1.059956412 0.978920254 1.000268854 0.97141721 1.180520453 1.42428934 2.024604731 1.016862054 1 12.72598855 -4.214362372 1.289872153 1.011573849 2.553498586 0.988483297 0.033654247 0.109406302 0.142394894 0.005128346 0.228148156 6.10E-05 4.214362372 1.541924737 up YGS(ph)IVDDERLSAEEMDER ddPTM_HeLa_Curcumin_4h_R1 2 YGSIVDDERLSAEEMDER 18 1 Q13576 Q13576 IQGAP2 Ras GTPase-activating-like protein IQGAP2 1 0 Y(0.05)GS(0.949)IVDDERLS(0.001)AEEMDER;Y(0.011)GS(0.989)IVDDERLSAEEMDER ; 67.579 0.0071934 11720900 2963.5 2198.38 2381.99 2859.5 2180.59 4036.8 3949.9 6429.1 3365.7 3314.1 TRUE FALSE FALSE 2728.935848 2388.398171 2470.268645 2847.668147 2154.587888 3199.522176 4060.723563 8389.302994 2996.491131 3429.264728 0.795778706 0.696475297 0.720349358 0.830401959 0.628294419 0.933005303 1.184138259 2.44638535 0.873799887 1 11.74368356 -4.213726402 2.146740106 0.849585217 3.005280665 0.951991635 0.110081687 0.146329973 0.673276321 0.019528226 0.630650038 6.11E-05 4.213726402 2.155695448 up RNDDIS(ph)ELEDLSELEDLKDAK ddPTM_HeLa_Curcumin_4h_R1 1 RNDDISELEDLSELEDLKDAK 21 2 Q9H4L7-2;Q9H4L7;D6RAY8 Q9H4L7-2 SMARCAD1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 1 0 RNDDIS(0.947)ELEDLS(0.053)ELEDLKDAK 72.271 0.0019459 4712200 1003 973.49 1134.4 1023.2 954.58 1120.1 949.03 894.06 1349.6 1183.3 TRUE FALSE FALSE 923.6114916 1057.634138 1176.441862 1018.96627 943.197257 887.7786339 975.6572276 1166.654778 1201.552257 1224.419587 0.754325969 0.863784073 0.960815945 0.832203503 0.770321928 0.725060791 0.796832424 0.952822701 0.981323943 1 10.25788231 -9.468800084 1.147514647 1.002213178 0.822919682 0.415111564 0.07460181 0.40210731 0.928284136 0.058530357 0.013699538 3.40E-10 9.468800084 -0.179293497 RNDDISELEDLS(ph)ELEDLKDAK ddPTM_HeLa_Curcumin_4h_R1 3 RNDDISELEDLSELEDLKDAK 21 2 Q9H4L7-2;Q9H4L7;D6RAY8 Q9H4L7-2 SMARCAD1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 1 0 RNDDISELEDLS(1)ELEDLKDAK;RNDDIS(0.012)ELEDLS(0.988)ELEDLKDAK;RNDDISELEDLS(1)ELEDLKDAK ;; 80.382 0.00033753 28608600 8468.99 6319.89 8591.74 8207.92 8368.68 9570.42 7935.62 7846.36 9336.86 8281.93 TRUE FALSE FALSE 7798.660505 6866.153131 8910.157442 8173.957802 8268.888957 7585.407011 8158.27214 10238.67904 8312.629818 8569.726451 0.910024439 0.801210303 1.039724838 0.95381782 0.964895321 0.885139923 0.951987463 1.194749809 0.969999435 1 13.06503344 -4.26219017 6.931234366 0.946793079 1.198515823 0.596932528 0.062235241 0.060766413 21.54267191 0.008879818 0.07176655 5.47E-05 4.26219017 0.251722743 RNEES(ph)DDDLDFDIDLEDTGGDHQMN ddPTM_HeLa_Curcumin_4h_R1 1 RNEESDDDLDFDIDLEDTGGDHQMN 25 1 Q96MD7-1 Q96MD7-1 1 0 RNEES(1)DDDLDFDIDLEDTGGDHQMN 128.8 2.83E-08 5232500 1793.8 1157.8 1278.6 1339.1 1274.5 1544 786.9 815.9 1667.8 1217.3 TRUE FALSE FALSE 1651.818837 1257.875073 1325.986041 1333.559159 1259.30242 1223.756996 808.9782962 1064.664154 1484.846513 1259.601084 1.311382514 0.998629716 1.052703159 1.058715474 0.99976289 0.971543301 0.642249603 0.845239153 1.178822828 1 10.29875119 -5.196235307 0.894955527 1.133914892 0.71158874 0.604997156 0.106577417 0.489450438 0.599969224 0.022433284 0.147102603 6.36E-06 5.196235307 -0.422326153 RNEIDAEPPAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 RNEIDAEPPAKR 12 2 Q8TDN6 Q8TDN6 BRIX1 Ribosome biogenesis protein BRX1 homolog 0 1 ; RNEIDAEPPAK(1)R;RNEIDAEPPAK(1)R 163.51 1.16E-06 22700000 4252.4 4721.2 4077.9 4295.2 4157.8 5629.9 3954 3205.7 5539.9 3954.7 FALSE TRUE FALSE 3915.818053 5129.279491 4229.030561 4277.4276 4108.220951 4462.195278 4064.938598 4183.103173 4932.18683 4092.125531 0.956915428 1.253451159 1.033455726 1.045282597 1.003933266 1.090434603 0.993356281 1.022232368 1.205287275 1 11.99863469 RNGS(ph)PTPAGSLGGGAVATAGGPGSR ddPTM_HeLa_Curcumin_4h_R1 1 RNGSPTPAGSLGGGAVATAGGPGSR 25 1 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 0 RNGS(0.987)PT(0.013)PAGSLGGGAVATAGGPGSR 121 5.05E-08 12068000 1445.9 1145.2 1215.2 1341.6 1139.9 1610.4 903.43 787.73 1472.4 1410.4 TRUE FALSE FALSE 1331.455489 1244.185985 1260.236381 1336.048815 1126.307437 1276.384887 928.7778143 1027.905251 1310.881404 1459.411295 0.912323684 0.852525939 0.863523796 0.915471066 0.771754639 0.874588878 0.636405801 0.704328694 0.89822616 1 10.51117081 -2.324190551 0.187595123 1.014306877 2.03E-12 0.653649095 0.060663769 10.68282797 0.183809769 0.062913721 2.846898479 0.00474034 2.324190551 -1.014306877 RNLEVLR ddPTM_HeLa_Curcumin_4h_R1 4 RNLEVLR 7 1 Q8N201 Q8N201 INTS1 Integrator complex subunit 1 0 0 ;;; ;;; 176.66 1.90E-06 17375200 11938.1 8014.1 10033.3 9296.6 10190.3 11505.3 9404.5 9198.8 10412.7 10020.1 FALSE FALSE TRUE 10993.18679 8706.803094 10405.14292 9258.133132 10068.78733 9118.971089 9668.364959 12003.47177 9270.452861 10368.29773 1.060269205 0.839752419 1.00355364 0.892927014 0.971112866 0.879505134 0.932492991 1.157709017 0.894115225 1 13.33989143 RNLLEDDS(ph)DEEEDFFLR ddPTM_HeLa_Curcumin_4h_R1 1 RNLLEDDSDEEEDFFLR 17 1 O75379 O75379 VAMP4 Vesicle-associated membrane protein 4 1 0 RNLLEDDS(1)DEEEDFFLR 117.55 0.00035002 3999000 1998.7 1747.4 1992.9 2301.4 2071.3 2211.9 1505.9 1216.9 2655.1 2162.5 TRUE FALSE FALSE 1840.500786 1898.43747 2066.758627 2291.877417 2046.6011 1753.127007 1548.151501 1587.927208 2363.842173 2237.646714 0.822516251 0.848408043 0.923630444 1.024235596 0.914622084 0.783469077 0.691865919 0.709641606 1.056396507 1 11.12776656 -5.0903869 2.901398635 0.91807059 0.702947674 0.649836416 0.071841848 0.146639778 2.373975002 0.011268218 0.034788468 8.12E-06 5.0903869 -0.215122916 RNPNTQLSTS(ph)FDETYIK ddPTM_HeLa_Curcumin_4h_R1 1 RNPNTQLSTSFDETYIK 17 1 Q9P242 Q9P242 NYAP2 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 1 0 RNPNTQLST(0.19)S(0.649)FDET(0.161)YIK 99.569 0.0010607 6441100 2222.9 1969.3 2048.4 1934.4 1718.4 2281.3 1936.6 976.81 2162.8 1930.8 TRUE FALSE FALSE 2046.955119 2139.517517 2124.315506 1926.395965 1697.909202 1808.132664 1990.935784 1274.634872 1925.546251 1997.895156 1.024555825 1.070885782 1.063276769 0.964212741 0.849849001 0.905018794 0.996516648 0.63798887 0.963787436 1 10.96426516 -5.908482911 3.680324559 1.020731264 0.862070101 0.466899796 0.088646819 0.160163902 4.236640307 0.012061319 0.022650175 1.23E-06 5.908482911 -0.158661163 RNPNTQLSTS(ph)FDETYIKK ddPTM_HeLa_Curcumin_4h_R1 2 RNPNTQLSTSFDETYIKK 18 2 Q9P242 Q9P242 NYAP2 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 1 0 RNPNTQLS(0.025)T(0.335)S(0.581)FDET(0.056)Y(0.003)IKK;RNPNT(0.011)QLS(0.056)T(0.32)S(0.607)FDET(0.005)Y(0.001)IKK ; 100.01 0.00108 59847000 1970.06 1699.57 1747.11 1682.41 1532.22 2276.32 1529.42 679.52 2011.73 1687.57 TRUE FALSE FALSE 1814.127672 1846.473258 1811.859434 1675.448633 1513.949277 1804.185573 1572.331409 886.7025199 1791.048252 1746.212932 1.038892588 1.057415865 1.037593641 0.959475561 0.866990073 1.033199067 0.900423643 0.507786023 1.025675746 1 10.77001378 -4.236944197 2.318728679 1.009116414 0.364892406 0.886058891 0.053021051 0.153801744 0.915793209 0.007837113 0.204603927 5.80E-05 4.236944197 -0.644224008 RNPS(ph)PDHSYK ddPTM_HeLa_Curcumin_4h_R1 1 RNPSPDHSYK 10 1 Q15696 Q15696 ZRSR2 U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 1 0 RNPS(0.999)PDHS(0.001)YK 77.192 0.016524 2068800 1325.3 1337.5 1166 1248.7 1518.1 1643.7 1298.7 804.19 1323 1196.1 TRUE FALSE FALSE 1220.401107 1453.10754 1209.212986 1243.53321 1499.997649 1302.778092 1335.138027 1049.383829 1177.87021 1237.664386 0.986051728 1.174072355 0.977012023 1.004741854 1.211958319 1.052610147 1.078756117 0.847874303 0.951687892 1 10.27340444 RNS(ph)EGSELSCTEGSLTSSLDSR ddPTM_HeLa_Curcumin_4h_R1 2 RNSEGSELSCTEGSLTSSLDSR 22 1 Q5T5U3;A0A087WW76;A0A452Q6Z5 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 0 RNS(0.999)EGS(0.001)ELSCTEGSLTSSLDSR;RNS(0.979)EGS(0.021)ELSCTEGSLTSSLDSR ; 161.04 2.37E-07 57271000 1322.01 1208.14 1197.89 1227.45 1375.18 1268.16 1313.77 610.09 1263.89 1316.99 TRUE FALSE FALSE 1217.371514 1312.566238 1242.284857 1222.371137 1358.781877 1005.129321 1350.63085 796.1036325 1125.244429 1362.755304 0.893316291 0.963170889 0.911597888 0.896985052 0.997084269 0.737571388 0.991102985 0.584186779 0.825712749 1 10.41231082 -3.898755134 2.180118978 0.935927408 1.19E-16 0.552145816 0.084537142 1.619128218 2.994645637 0.010711106 4.377839165 0.000126254 3.898755134 -0.935927408 RNS(ph)FSENEK ddPTM_HeLa_Curcumin_4h_R1 4 RNSFSENEK 9 1 Q9HCG8 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 1 0 RNS(0.999)FS(0.001)ENEK;RNS(0.999)FS(0.001)ENEK;RNS(0.987)FS(0.013)ENEK;RNS(0.993)FS(0.007)ENEK ;;; 108.98 0.007087 413341000 15256.7 13524 14073 14484.6 13380.6 14489.8 12150.4 9315.2 13799.3 13779.7 TRUE FALSE FALSE 14049.1161 14692.9543 14594.55776 14424.66656 13221.04508 11484.45215 12491.30752 12155.3616 12285.55131 14258.54355 0.985312143 1.030466699 1.023565816 1.01165077 0.927236715 0.805443565 0.876057746 0.852496719 0.861627365 1 13.799539 -5.526855552 3.743425497 0.99946202 0.848482527 0.617251597 0.048730431 0.047389961 1.455472063 0.003327127 0.007338073 2.97E-06 5.526855552 -0.150979493 RNS(ph)FTPLSSSNTIR ddPTM_HeLa_Curcumin_4h_R1 2 RNSFTPLSSSNTIR 14 1 O60825 O60825 PFKFB2 "6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase" 1 0 RNS(1)FTPLSSSNTIR;RNS(1)FTPLSSSNTIR ; 227.92 3.73E-20 68007000 4650.2 3469 4491.1 3592.8 3596.4 6168.1 5606.9 3278.3 4902.9 4748.6 TRUE FALSE FALSE 4282.131763 3768.844902 4657.544117 3577.933946 3553.515279 4888.766531 5764.214524 4277.838579 4365.064136 4913.613497 0.87148323 0.767021034 0.94788573 0.728167559 0.723197964 0.99494324 1.173111098 0.870609498 0.888361313 1 12.26256866 -5.015090668 24.54729092 0.895309823 1.037402025 0.235496485 0.116014649 655.2926268 1065940.893 0.017743728 0.047065635 9.66E-06 5.015090668 0.142092203 RNS(ph)LEGYSR ddPTM_HeLa_Curcumin_4h_R1 2 RNSLEGYSR 9 1 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 0 RNS(1)LEGYSR;RNS(1)LEGYSR ; 93.839 0.0078468 92355000 4956 4094.4 4145.2 4035.4 4353 5266.9 5639.2 5129.3 4399 4247.8 TRUE FALSE FALSE 4563.72737 4448.301692 4298.824758 4018.702584 4301.093318 4174.48557 5797.420775 6693.199958 3916.440706 4395.410734 1.038293722 1.012033223 0.978025722 0.91429512 0.978541843 0.949737311 1.318971338 1.522770081 0.891029518 1 12.10178227 -4.593962267 3.346043322 1.00121499 1.495888058 0.921420427 0.053399905 0.039983521 0.8557896 0.006622876 0.033638943 2.55E-05 4.593962267 0.494673068 RNS(ph)S(ph)SPVS(ph)PASVPGQR ddPTM_HeLa_Curcumin_4h_R1 1 RNSSSPVSPASVPGQR 16 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 3 0 RNS(0.817)S(0.594)S(0.593)PVS(0.944)PAS(0.052)VPGQR 84.195 0.0037969 0 2241.3 2317 2202.4 2097.5 2026.7 2406.9 2447.4 2777.4 2486.4 2165.7 TRUE FALSE FALSE 2063.89874 2517.271156 2284.022881 2088.821101 2002.532926 1907.681809 2516.067457 3624.216474 2213.648141 2240.957914 0.920989514 1.123301397 1.019217214 0.932110812 0.893605772 0.851279623 1.122764262 1.617262177 0.987813348 1 11.12989984 -4.305718026 3.027008323 0.964558676 1.690019988 0.878130657 0.072739736 0.080849226 1.135144659 0.010565939 0.132594392 4.95E-05 4.305718026 0.725461312 PAEKPAETPVATS(ph)PTATDSTSGDSSR ddPTM_HeLa_Curcumin_4h_R1 2 PAEKPAETPVATSPTATDSTSGDSSR 26 1 P54727;H0Y579;P54727-2 P54727 RAD23B UV excision repair protein RAD23 homolog B 1 0 PAEKPAETPVAT(0.111)S(0.609)PT(0.274)AT(0.004)DS(0.001)T(0.001)SGDSSR;PAEKPAETPVAT(0.333)S(0.458)PT(0.165)AT(0.032)DS(0.003)T(0.004)S(0.004)GDSSR ; 135.02 3.23E-08 24351900 2544.2 2613.5 2835.3 2690.4 2762 3350.9 3512.4 6074.3 2667.7 2454.29 TRUE FALSE FALSE 2342.823885 2839.399294 2940.378712 2679.267838 2729.064954 2655.885568 3610.948491 7926.326107 2375.059984 2539.576395 0.922525461 1.118060201 1.157822509 1.055005805 1.074614239 1.045798651 1.421870395 3.121121351 0.935218956 1 11.31037216 -4.21212378 2.222846186 1.004958443 3.843466164 0.984999201 0.076716976 0.070689076 0.355317406 0.013005055 0.411822711 6.14E-05 4.21212378 2.83850772 up VLSST(ph)SEEDEPGVVK ddPTM_HeLa_Curcumin_4h_R1 2 VLSSTSEEDEPGVVK 15 0 Q8NI08-2;Q8NI08;Q8NI08-7;Q8NI08-4;Q8NI08-3 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 0 VLS(0.159)S(0.159)T(0.557)S(0.124)EEDEPGVVK;VLS(0.042)S(0.037)T(0.461)S(0.461)EEDEPGVVK ; 271.64 1.52E-50 25537800 6718.8 5900.3 5603.1 6742.5 6327.7 7880.9 6707.9 8851.4 6231.9 5480.3 TRUE FALSE FALSE 6186.99989 6410.295641 5810.755815 6714.601322 6252.24631 6246.312504 6896.105621 11550.15111 5548.276161 5670.740017 1.091039242 1.130416069 1.024690922 1.184078498 1.102545046 1.101498655 1.216085661 2.036797857 0.978404255 1 12.4693213 -4.211462262 2.441175282 1.065932557 2.336572606 0.95835108 0.05966307 0.093099982 0.601193024 0.008841529 0.259363195 6.15E-05 4.211462262 1.270640049 up RNS(ph)SS(ph)PVSPASVPGQR ddPTM_HeLa_Curcumin_4h_R1 1 RNSSSPVSPASVPGQR 16 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 2 0 RNS(0.998)S(0.234)S(0.576)PVS(0.192)PAS(0.001)VPGQR 133.23 0.00068104 24739000 6867.5 6341.9 5995.2 6313.1 6804.2 9414 8948.8 8049.9 7620.2 6804.3 TRUE FALSE FALSE 6323.930128 6890.065577 6217.387386 6286.978065 6723.064359 7461.430282 9199.879244 10504.27745 6784.283125 7040.748919 0.89818998 0.978598393 0.883057677 0.892941665 0.954879152 1.059749519 1.306662026 1.491926154 0.963574075 1 12.78151318 -4.658342882 1.690948623 0.942610198 1.520067117 0.962236241 0.036895509 0.081072163 0.369879584 0.006919719 0.059213455 2.20E-05 4.658342882 0.577456919 VVDVEEQQLEES(ph)GPHDLTETSYLPR ddPTM_HeLa_Curcumin_4h_R1 2 VVDVEEQQLEESGPHDLTETSYLPR 25 0 P38398-8;P38398-4;P38398;P38398-7;K7EPC7;H0Y8B8;B7ZA85;E7EUM2;A0A2R8Y7V5;P38398-6;P38398-5;P38398-3 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 0 VVDVEEQQLEES(1)GPHDLTETSYLPR;VVDVEEQQLEES(1)GPHDLTETSYLPR ; 133.56 4.74E-08 46786000 3289.7 2735.4 2909.8 2981.3 2676.8 4058.8 2717.6 796.29 3447.7 2691.9 TRUE FALSE FALSE 3029.316774 2971.835787 3017.639748 2968.964171 2644.880908 3216.959128 2793.848542 1039.075155 3069.495936 2785.443325 1.087552831 1.066916624 1.08336067 1.065885687 0.949536788 1.154918177 1.003017551 0.373037622 1.101977523 1 11.44369125 -4.26427114 4.776135118 1.049225958 0.3362895 0.934462358 0.054437552 0.029761681 1.917650927 0.007319256 0.070148184 5.44E-05 4.26427114 -0.712936459 down SDSPVPTAPTSGGPKPS(ph)TASAVPELATDPELEKK ddPTM_HeLa_Curcumin_4h_R1 1 SDSPVPTAPTSGGPKPSTASAVPELATDPELEKK 34 2 Q86U44;B4E349;F5H6D8;B4DTN4 Q86U44 METTL3 N6-adenosine-methyltransferase 70 kDa subunit 1 0 S(0.005)DS(0.021)PVPT(0.013)APT(0.082)S(0.082)GGPKPS(0.266)T(0.266)AS(0.266)AVPELATDPELEKK 64.152 6.41E-05 147860000 9178.4 7279.9 8217.3 8587.3 7316.3 7634.5 6089.8 1499.9 8656.8 6876.5 TRUE FALSE FALSE 8451.919955 7909.142117 8521.840367 8551.768028 7229.057901 6051.018641 6260.663398 1957.212605 7707.170698 7115.457863 1.187825171 1.111543666 1.197651723 1.201857729 1.015965246 0.850404676 0.879867961 0.275064886 1.083158786 1 12.79674088 -4.263982146 1.156825784 1.103676901 5.19E-14 0.877398894 0.092186923 0.462005014 0.498529564 0.01577628 0.614957386 5.45E-05 4.263982146 -1.103676901 down RNS(ph)SSSSSPSERPR ddPTM_HeLa_Curcumin_4h_R1 3 RNSSSSSSPSERPR 14 2 B7WPE2;Q32P44;G3V1D0;H0Y3M3;Q32P44-2 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 0 RNS(0.863)S(0.134)S(0.003)SSSPSERPR;RNS(0.972)S(0.026)S(0.002)SSSPSERPR;RNS(0.983)S(0.013)S(0.004)SSSPSERPR ;; 112.12 0.0010768 8158100 121.35 360.63 413.18 220.059 262.114 462.68 351.689 240.86 278.223 308.98 TRUE FALSE FALSE 111.7450195 391.8012503 428.4928143 219.1484542 258.9884617 366.7149525 361.5564468 314.2971052 247.702633 319.717032 0.349512251 1.225462553 1.340225172 0.685445041 0.810055255 1.146998489 1.130863891 0.983047738 0.774755825 1 8.320651791 -7.244270277 24.97093047 0.692825215 1.041533928 0.304861763 0.233427508 901.2238808 1310750.931 0.050015207 0.061172772 5.70E-08 7.244270277 0.348708713 RNS(ph)TIVLR ddPTM_HeLa_Curcumin_4h_R1 1 RNSTIVLR 8 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 RNS(0.815)T(0.185)IVLR 112.83 0.004906 6637400 1439.2 1279.9 1357.6 1459.9 1662.9 1652.2 2081.4 1407.3 1638 1260.7 TRUE FALSE FALSE 1325.285801 1390.528853 1407.91385 1453.859321 1643.071004 1309.515096 2139.798482 1836.379292 1458.315498 1304.509231 1.015926733 1.065940217 1.079267066 1.114487568 1.25953191 1.003837355 1.640309191 1.407716594 1.117903548 1 10.34929144 -4.433732285 0.543705803 1.007336476 1.818077824 0.566178145 0.130209701 1.32733592 0.295979454 0.022171409 0.653978968 3.68E-05 4.433732285 0.810741349 SVS(ph)VDSGEQR ddPTM_HeLa_Curcumin_4h_R1 2 SVSVDSGEQR 10 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 0 S(0.006)VS(0.994)VDSGEQR;S(0.028)VS(0.965)VDS(0.007)GEQR ; 151.13 0.00071048 78304000 3876.9 3309.3 3855 3848.1 4240 6541.5 11366.9 22138.3 0 4559.8 TRUE FALSE FALSE 3570.039274 3595.341146 3997.869691 3832.177582 4189.440769 5184.719162 11685.82462 28888.16576 0 4718.252711 0.756644354 0.762006905 0.847319959 0.812202698 0.887922082 1.098864236 2.476727157 6.122640632 0 1 12.20403698 -4.209928792 1.708534277 0.862241841 8.435376113 0.970584995 0.283632315 0.049192141 0.125377227 0.016124574 0.63098298 6.17E-05 4.209928792 7.573134271 up RNS(ph)TTIMSR ddPTM_HeLa_Curcumin_4h_R1 1 RNSTTIMSR 9 1 Q7Z309;Q7Z309-2;G1UD79;Q7Z309-4;Q7Z309-3 Q7Z309 FAM122B;SPACIA2 Protein FAM122B 1 0 RNS(0.999)T(0.001)TIMSR 110.64 0.0041921 70694000 1423.1 916.49 733.86 867.42 925.42 1347.1 1092.2 1219.7 1004.3 897.87 TRUE FALSE FALSE 1310.460133 995.7073118 761.0574972 863.8308459 914.3849709 1067.696275 1122.844192 1591.580915 894.1308026 929.0709157 1.410506035 1.071723692 0.819159748 0.929779236 0.98419287 1.149208588 1.208566724 1.71308873 0.962392415 1 9.859644911 -2.330906288 5.787466752 1.159045171 1.268754783 0 0.253573852 0 0 0.03535736 0 0.004667601 2.330906288 0.109709612 DMSPLS(ph)ETEMALGKDVTPPPETEVVLIK ddPTM_HeLa_Curcumin_4h_R1 2 DMSPLSETEMALGKDVTPPPETEVVLIK 28 1 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 DMS(0.299)PLS(0.318)ET(0.318)EMALGKDVT(0.063)PPPETEVVLIK;DMS(0.169)PLS(0.631)ET(0.191)EMALGKDVT(0.008)PPPETEVVLIK ; 54.855 0.0039312 0 1467.97 1330.68 1294.45 1545.43 1463.93 1955.6 1487.45 2237.1 1865.11 1302.3 TRUE FALSE FALSE 1351.778626 1445.69805 1342.423456 1539.03542 1446.473591 1549.986516 1529.183844 2919.181492 1660.512099 1347.554828 1.003134416 1.072830596 0.996192086 1.142094843 1.073406114 1.150221485 1.134784138 2.166280311 1.232240844 1 10.39612826 -4.209698649 2.779837655 1.029748829 2.468319972 0.929985638 0.087648075 0.072393254 0.66770052 0.00938128 0.249639706 6.17E-05 4.209698649 1.438571143 up S(ph)PISVPGGSALISNLGK ddPTM_HeLa_Curcumin_4h_R1 2 SPISVPGGSALISNLGK 17 0 P51610-2;P51610;A6NEM2;P51610-4 P51610-2 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 0 S(0.998)PIS(0.002)VPGGSALISNLGK;S(1)PISVPGGSALISNLGK ; 169.15 7.57E-05 74975000 3538.8 2899.7 3009.1 2780.8 3883.3 4964.7 4302.8 9975.2 2940.4 3086.1 TRUE FALSE FALSE 3258.700246 3150.337147 3120.619893 2769.293786 3836.994184 3934.965256 4423.524988 13016.59256 2617.845477 3193.341745 1.020467117 0.986533042 0.977227037 0.867208713 1.201560775 1.232240571 1.385233821 4.076166473 0.819782436 1 11.64085124 -4.209303236 2.619945842 1.021257779 4.954038217 0.981775303 0.124353412 0.048498701 0.37835876 0.015678843 0.439728055 6.18E-05 4.209303236 3.932780438 up RNS(ph)VTPLASPEPTKKPR ddPTM_HeLa_Curcumin_4h_R1 1 RNSVTPLASPEPTKKPR 17 3 Q9H178;Q5W015;Q5VX20;A0A1W2PR17;Q16875-3;Q16875-2;Q16875;Q16875-4 Q9H178 PFKFB3 "6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;6-phosphofructo-2-kinase;Fructose-2,6-bisphosphatase" 1 0 RNS(0.96)VT(0.039)PLAS(0.001)PEPTKKPR 57.973 0.01854 16647000 2999.2 2133.7 2575.4 2552.2 2573.4 3330.4 2937.5 4532.9 3995.4 3523.9 TRUE FALSE FALSE 2761.810155 2318.12752 2670.84659 2541.639673 2542.713886 2639.637499 3019.918344 5914.960343 3557.114616 3646.355263 0.757416641 0.635738252 0.732470206 0.697035667 0.697330266 0.723911223 0.828201897 1.622156898 0.975526069 1 11.83223941 -1.250804829 11.72472233 0.855605097 1.185556511 0 0.27645372 0 0 0.035144444 0 0.056130017 1.250804829 0.329951414 RNSNS(ph)PPS(ph)PSSMNQR ddPTM_HeLa_Curcumin_4h_R1 1 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 2 0 RNS(0.002)NS(0.997)PPS(0.92)PS(0.068)S(0.012)MNQR 73.593 0.012579 1751000 891.92 479.95 637.56 802.37 887.01 833.02 646.85 475.95 1211.3 820.57 TRUE FALSE FALSE 821.3235909 521.4347394 661.1885345 799.0500055 876.4329851 660.2422619 664.9988701 621.064964 1078.423421 849.0847464 0.967304612 0.614113893 0.778707352 0.941072147 1.03220908 0.77759289 0.783194932 0.731452269 1.270101041 1 9.729764745 -7.485865723 24.74463734 0.985575655 0.816757928 0.394896844 0.139816259 350.2993801 234190.6942 0.019347583 0.021625619 3.27E-08 7.485865723 -0.168817727 RNSNSPPS(ph)PSSMNQR ddPTM_HeLa_Curcumin_4h_R1 2 RNSNSPPSPSSMNQR 15 1 Q7Z5L9;Q7Z5L9-2;Q7Z5L9-3 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 0 RNS(0.003)NS(0.037)PPS(0.884)PS(0.07)S(0.006)MNQR;RNSNS(0.112)PPS(0.663)PS(0.112)S(0.112)MNQR ; 89.353 0.0038467 5805500 1776.03 1303.33 1297.17 1409.93 1264.49 1756.82 1026.38 951.56 1798.25 1709.81 TRUE FALSE FALSE 1635.455351 1415.984038 1345.244261 1404.096083 1249.411783 1392.435729 1055.17746 1241.686264 1600.986474 1769.22577 0.924390419 0.800341065 0.7603576 0.793621768 0.706191264 0.787031114 0.596406337 0.701824654 0.904907955 1 10.78890245 -6.869948631 0.461892354 1.001051904 0.659370577 0.761904313 0.055223814 0.226857268 0.111282747 0.017608964 0.029438369 1.35E-07 6.869948631 -0.341681327 RNSS(ph)EASSGDFLDLK ddPTM_HeLa_Curcumin_4h_R1 1 RNSSEASSGDFLDLK 15 1 Q9UK76;J3KT51;Q9UK76-2;Q9UK76-3;J3KSH8 Q9UK76;Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 1 0 RNS(0.454)S(0.542)EAS(0.002)S(0.002)GDFLDLK 97.235 0.0023009 2034600 794.02 860.4 778.67 827.82 1024.2 1105 990.85 1104.9 676.84 747.42 TRUE FALSE FALSE 731.1724792 934.7691421 807.5281952 824.3947002 1011.987084 875.8105441 1018.650584 1441.778924 602.5923454 773.3927894 0.945408968 1.208660276 1.044137218 1.065945677 1.308503386 1.13242657 1.317119319 1.864225971 0.779154336 1 9.595057503 -1 0.513210309 0.994646936 29.38777725 0.809713354 0.122167302 26.09543026 0.242006944 0.019784045 808.5271772 0.1 1 28.39313032 NGSMGS(ph)PVNQQPK ddPTM_HeLa_Curcumin_4h_R1 1 NGSMGSPVNQQPK 13 0 A0A0A0MRW1;A0A0A0MRW0;Q8IW50-3;Q8IW50-2;Q8IW50-4;Q5T586;A0A0A0MRW2;Q5T593;A0A0A0MRW3;Q8IW50-5;Q8IW50-6;Q8IW50;A0A0A0MRV9;Q8IW50-7 A0A0A0MRW1 FAM219A Protein FAM219A 1 0 NGS(0.029)MGS(0.971)PVNQQPK 102.9 0.0064931 945980 580.63 462.6 538.96 603.77 525.13 796.08 516.09 140.16 588.78 531.29 TRUE FALSE FALSE 534.6725228 502.5850827 558.9343317 601.2717597 518.8681677 630.9640343 530.5700964 182.8941388 524.1923071 549.752288 0.972569891 0.914202803 1.016702147 1.093713974 0.943821752 1.147724254 0.965107573 0.332684634 0.953506367 1 9.102637893 -4.263821319 5.427359615 0.998702863 0.308200648 0.900477326 0.066719684 0.029450509 3.233898454 0.008561883 0.075299813 5.45E-05 4.263821319 -0.690502216 down RNSSS(ph)PVSPASVPGQR ddPTM_HeLa_Curcumin_4h_R1 1 RNSSSPVSPASVPGQR 16 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 0 RNS(0.001)S(0.086)S(0.913)PVSPASVPGQR 113.05 0.00065472 9975800 1148.3 880.65 901.95 1158.1 1059.9 1274.9 578.26 444.17 1201.4 1094.3 TRUE FALSE FALSE 1057.410843 956.7694619 935.3770604 1153.308089 1047.261385 1010.471369 594.4844193 579.5953883 1069.609426 1132.326844 0.933838891 0.844958739 0.826066313 1.018529319 0.924875526 0.892384893 0.525011327 0.51186227 0.944611913 1 10.14507473 -4.7869494 4.041524991 0.947631072 0.507225996 0.884119028 0.058391696 0.048648091 1.724234612 0.009370409 0.033999993 1.63E-05 4.7869494 -0.440405076 RNT(ph)LQLHR ddPTM_HeLa_Curcumin_4h_R1 1 RNTLQLHR 8 1 P61313;E7ERA2 P61313 RPL15 60S ribosomal protein L15;Ribosomal protein L15 1 0 RNT(1)LQLHR 89.827 0.0112 10010000 2381.7 2283.4 1253.5 1732.1 1556.1 2015.8 1439.1 1010.4 2020.9 1355.3 TRUE FALSE FALSE 2193.185932 2480.766921 1299.955813 1724.933029 1537.544524 1597.700357 1479.477273 1318.466309 1799.212326 1402.396574 1.563884262 1.768948218 0.926953072 1.229989477 1.096369281 1.139264304 1.054963553 0.94015226 1.282955449 1 10.45367866 RNVPQEESLEDS(ph)DVDADFK ddPTM_HeLa_Curcumin_4h_R1 2 RNVPQEESLEDSDVDADFK 19 1 O00505 O00505 KPNA3 Importin subunit alpha-4 1 0 RNVPQEESLEDS(1)DVDADFK;RNVPQEESLEDS(1)DVDADFK ; 182.19 1.13E-07 26394000 6477.7 5269.9 5840.4 6438.2 6185 6342.2 4974 3999.6 6311.5 5700.8 TRUE FALSE FALSE 5964.98321 5725.406674 6056.850362 6411.560434 6111.247915 5026.756229 5113.557053 5219.059628 5619.144241 5898.902376 1.011202225 0.970588477 1.026775826 1.086907364 1.035997466 0.852151114 0.866865855 0.884750975 0.952574544 1 12.52623082 -5.259540843 24.99984804 1.012436907 0.867816961 0.779517408 0.035115005 52.27302329 688321.1338 0.004563105 0.011023766 5.50E-06 5.259540843 -0.144619946 RNVSSFPDDAT(ph)SPLQENR ddPTM_HeLa_Curcumin_4h_R1 1 RNVSSFPDDATSPLQENR 18 1 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 0 RNVSSFPDDAT(0.5)S(0.5)PLQENR 117.6 0.00022066 8037300 2920.4 2208 2448.5 2842.9 2202.1 3058.7 2316.5 1864.9 2666.7 2704.1 TRUE FALSE FALSE 2689.247258 2398.849681 2539.243564 2831.136833 2175.841396 2424.291141 2381.494755 2433.499425 2374.169682 2798.067274 0.961108864 0.857323805 0.907499111 1.011818715 0.777622974 0.866416317 0.851121336 0.869707261 0.848503431 1 11.45021493 -6.895905778 0.386821888 1.004216082 0.837529898 0 0.072247887 0.727014872 0.27211657 0.028146409 0.04605411 1.27E-07 6.895905778 -0.166686184 RNVSSFPDDATS(ph)PLQENR ddPTM_HeLa_Curcumin_4h_R1 1 RNVSSFPDDATSPLQENR 18 1 P52292;J3QLL0;J3KS65 P52292 KPNA2 Importin subunit alpha-1 1 0 RNVSSFPDDAT(0.263)S(0.736)PLQENR 97.662 0.00083499 13180000 1012.4 534.3 815.64 702.84 633.11 838.21 709.35 593.76 853.97 489.87 TRUE FALSE FALSE 932.2674717 580.4825112 845.8683359 699.9318343 625.5605767 664.3557974 729.2524519 774.7946907 760.2916275 506.892946 1.839180204 1.145177726 1.668731716 1.380827727 1.234107876 1.310643209 1.438671533 1.528517405 1.499905717 1 8.985537277 -9.655084769 1.507190719 1.000909893 1.490840348 0 0.247878023 0.327089463 1.34047019 0.158383385 0.035981667 2.21E-10 9.655084769 0.489930456 RPAAAAAAGSAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 6 RPAAAAAAGSASPR 14 1 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 0 RPAAAAAAGS(0.011)AS(0.989)PR;RPAAAAAAGS(0.004)AS(0.996)PR;RPAAAAAAGS(0.05)AS(0.95)PR;RPAAAAAAGS(0.02)AS(0.98)PR;RPAAAAAAGSAS(1)PR;RPAAAAAAGS(0.024)AS(0.976)PR ;;;;; 182.7 0.00014588 166395700 6798.59 6074.2 6169.18 6058.72 6960.05 7329.26 5327.25 4028.92 6005.67 5808.56 TRUE FALSE FALSE 6260.474428 6599.226782 6397.815238 6033.650622 6877.05595 5809.088858 5476.718297 5257.319161 5346.863026 6010.407028 1.041605735 1.097966702 1.064456235 1.003867225 1.144191386 0.966505069 0.911205892 0.874702684 0.889600821 1 12.55324698 -4.906699175 3.480604011 1.036049162 0.89185186 0.434603106 0.064323739 0.117761858 2.77722698 0.006631353 0.022769371 1.24E-05 4.906699175 -0.144197302 RPAEATSSPT(ph)SPERPR ddPTM_HeLa_Curcumin_4h_R1 1 RPAEATSSPTSPERPR 16 2 Q9BU76 Q9BU76 MMTAG2 Multiple myeloma tumor-associated protein 2 1 0 RPAEATS(0.002)S(0.014)PT(0.918)S(0.066)PERPR 98.804 0.0067713 86666000 779.92 1022.2 621.86 752.24 833.1 954.28 798.42 1115.3 1071.3 851.92 TRUE FALSE FALSE 718.188509 1110.554413 644.9066786 749.1274302 823.1658266 756.351571 820.8215164 1455.349836 953.7810703 881.5241566 0.814712227 1.259811662 0.731581402 0.849809304 0.933798377 0.858004361 0.931138994 1.650947197 1.081968161 1 9.783856294 -4.261702139 6.606335714 0.916029397 1.664654909 0.686790591 0.143223514 0.044544294 12.27867951 0.017980532 0.14859879 5.47E-05 4.261702139 0.748625511 RPAEDMEEEQAFK(ac)R ddPTM_HeLa_Curcumin_4h_R1 4 RPAEDMEEEQAFKR 14 2 P61978-3;P61978;P61978-2;Q5T6W2;S4R457 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 1 ;;; RPAEDMEEEQAFK(1)R;RPAEDMEEEQAFK(1)R;RPAEDMEEEQAFK(1)R;RPAEDMEEEQAFK(1)R 278.36 2.73E-94 31653900 2468.3 2421.13 2021.947 2170.46 2795.45 3978.4 3199.475 3045.41 3353.98 2154.51 FALSE TRUE FALSE 2272.93145 2630.401689 2096.882135 2161.479212 2762.116085 3153.234994 3289.243658 3973.94149 2986.056785 2229.379062 1.019535659 1.179880862 0.940567789 0.969543156 1.238962064 1.41440056 1.475407979 1.782532884 1.339411873 1 11.12242622 -4.806936053 0.866011404 1.011364578 1.871481143 0.739929842 0.131264282 0.238387381 0.212202002 0.012879599 0.162199336 1.56E-05 4.806936053 0.860116565 RLSSSSATLLNS(ph)PDR ddPTM_HeLa_Curcumin_4h_R1 2 RLSSSSATLLNSPDR 15 1 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;A0A087WZ40 Q14244-3 MAP7 Ensconsin 1 0 RLSSSSATLLNS(1)PDR;RLSSSSATLLNS(1)PDR ; 146.67 0.0002231 35753000 5315.1 4238.9 4540.2 4864.3 5051.3 6777.4 4562.6 1548.1 5727.3 4583.1 TRUE FALSE FALSE 4894.404227 4605.291628 4708.463806 4844.172815 4991.066547 5371.690843 4690.614276 2020.108563 5099.029519 4742.362384 1.032060359 0.971096524 0.992851964 1.021468294 1.052443095 1.132703579 0.989088116 0.42597094 1.075208748 1 12.21139019 -4.263756333 5.229740238 1.021385023 0.401257387 0.941982497 0.044971395 0.024147567 2.259490765 0.005947882 0.053603737 5.45E-05 4.263756333 -0.620127636 down RPAS(ph)PSS(ph)PEHLPATPAESPAQR ddPTM_HeLa_Curcumin_4h_R1 2 RPASPSSPEHLPATPAESPAQR 22 1 Q9H7L9 Q9H7L9 SUDS3 Sin3 histone deacetylase corepressor complex component SDS3 2 0 RPAS(0.571)PS(0.571)S(0.858)PEHLPATPAESPAQR;RPAS(0.933)PS(0.313)S(0.753)PEHLPATPAESPAQR ; 75.868 0.00057241 158478000 1943.53 1325.35 1618.47 1389.47 1564.28 1790.87 1617.74 1357.48 1881.9 1178.71 TRUE FALSE FALSE 1789.69755 1439.907348 1678.451922 1383.720741 1545.626983 1419.423375 1663.12943 1771.369403 1675.460278 1219.670085 1.467362012 1.180571178 1.376152406 1.134504124 1.267250056 1.163776494 1.36358959 1.452334877 1.373699576 1 10.25227524 -9.536844466 1.292152003 0.999629389 1.311579629 0 0.158780205 0.305342553 0.911310131 0.083490089 0.019792842 2.91E-10 9.536844466 0.31195024 RPAS(ph)TAGLPTAGLPTATGLPSGAPPGVATIR ddPTM_HeLa_Curcumin_4h_R1 2 RPASTAGLPTAGLPTATGLPSGAPPGVATIR 31 1 Q765P7;A0A087WXN9 Q765P7 MTSS1L MTSS1-like protein 1 0 RPAS(0.48)T(0.48)AGLPT(0.038)AGLPT(0.001)ATGLPSGAPPGVATIR;RPAS(0.584)T(0.397)AGLPT(0.019)AGLPTATGLPSGAPPGVATIR ; 76.853 1.05E-05 51687000 1155.35 849.85 1150.97 1410.24 936.86 1494.19 1233.53 644.58 1459.82 1284.59 TRUE FALSE FALSE 1063.902828 923.3072471 1193.625961 1404.404801 925.6885564 1184.278151 1268.139532 841.1094747 1299.681398 1329.229407 0.80039068 0.694618433 0.897983414 1.05655562 0.696409929 0.890950911 0.954041135 0.632779767 0.977770573 1 10.3763744 -9.289796108 1.026971906 0.999621359 0.834101609 0.211774459 0.123225961 0.665810557 1.263085524 0.079176736 0.021524769 5.13E-10 9.289796108 -0.16551975 RPAS(ph)VSSSAAVEHEQR ddPTM_HeLa_Curcumin_4h_R1 3 RPASVSSSAAVEHEQR 16 1 Q7Z5L9;Q7Z5L9-2 Q7Z5L9 IRF2BP2 Interferon regulatory factor 2-binding protein 2 1 0 RPAS(0.428)VS(0.257)S(0.257)S(0.057)AAVEHEQR;RPAS(0.982)VS(0.016)S(0.002)SAAVEHEQR;RPAS(0.946)VS(0.039)S(0.014)SAAVEHEQR ;; 147.17 0.00017019 185347800 3646.57 3967.11 3770.18 3850.21 3990.08 5505.3 3041.01 2961.01 4340.16 3491.6 TRUE FALSE FALSE 3357.940137 4310.009311 3909.906187 3834.278851 3942.500902 4363.438722 3126.332556 3863.808318 3864.055307 3612.93284 0.929422241 1.192939228 1.082197306 1.061264912 1.091218984 1.207727604 0.865317097 1.069438179 1.069506542 1 11.81895472 -7.291828061 24.99817906 0.966671611 1.077616788 0.107307479 0.094293615 692.3022015 569496.362 0.015033943 0.017192915 5.11E-08 7.291828061 0.110945177 RPDDVPLSLS(ph)PSKR ddPTM_HeLa_Curcumin_4h_R1 2 RPDDVPLSLSPSKR 14 2 F8WDB4;Q9UFC0 F8WDB4 LRWD1 Leucine-rich repeat and WD repeat-containing protein 1 1 0 RPDDVPLS(0.001)LS(0.904)PS(0.096)KR;RPDDVPLS(0.169)LS(0.699)PS(0.133)KR ; 116.61 0.0014961 522470000 4773.9 4258.7 3873 4357.2 3923 4756.1 4026 2500.2 5149.2 3528.2 TRUE FALSE FALSE 4396.040778 4626.803052 4016.536787 4339.171061 3876.220787 3769.631248 4138.958725 3262.49947 4584.345643 3650.804687 1.204129268 1.267337874 1.10017849 1.188551958 1.061744223 1.032548046 1.133711354 0.893638458 1.255708271 1 11.83399877 -4.25768992 23.95503696 1.111281723 0.893638305 0.367367025 0.090258993 197.853395 1263969.813 0.013444594 0.132757363 5.52E-05 4.25768992 -0.217643418 RPDHSGGS(ph)PSPPTSEPAR ddPTM_HeLa_Curcumin_4h_R1 2 RPDHSGGSPSPPTSEPAR 18 1 Q8TAD8 Q8TAD8 SNIP1 Smad nuclear-interacting protein 1 1 0 RPDHS(0.004)GGS(0.987)PS(0.01)PPTSEPAR;RPDHS(0.017)GGS(0.965)PS(0.017)PPTSEPAR ; 96.579 0.00089687 8008430 1597.15 1450.89 1463.823 1285.46 1541.46 1901.37 1513.24 789.507 1788.94 1502.64 TRUE FALSE FALSE 1470.733892 1576.298467 1518.073568 1280.141107 1523.079096 1507.004429 1555.697442 1030.22405 1592.697758 1554.856628 0.945896789 1.013790235 0.976343118 0.82331778 0.979562404 0.969224044 1.000540766 0.662584595 1.024337375 1 10.60256584 -4.257712733 24.97444777 0.967945249 0.662584477 0.74614877 0.053835092 132.8994696 890599.0455 0.007077579 0.071169747 5.52E-05 4.257712733 -0.305360772 RPDPDS(ph)DEDEDYER ddPTM_HeLa_Curcumin_4h_R1 2 RPDPDSDEDEDYER 14 1 H0Y6J6;Q5W012;Q96I25;Q5W011;Q5W010 H0Y6J6 RBM17 Splicing factor 45 1 0 RPDPDS(1)DEDEDYER;RPDPDS(1)DEDEDYER ; 138.98 0.0012569 141648000 9896.4 9378.6 10640.3 10077 11621.1 11492.7 9042.8 9007.1 9565.7 8897.7 TRUE FALSE FALSE 9113.089497 10189.24439 11034.63888 10035.30404 11482.52597 9108.984471 9296.516631 11753.32333 8516.366642 9206.894413 0.989811449 1.106697214 1.198519108 1.089977097 1.247166032 0.989365584 1.009734251 1.276578486 0.924998839 1 13.16849889 -7.214936309 4.81468453 0.995031272 1.127555868 0.390745806 0.090034017 0.173354049 9.295916832 0.014005862 0.017026174 6.10E-08 7.214936309 0.132524596 RPDPDS(ph)DEDEDYERER ddPTM_HeLa_Curcumin_4h_R1 2 RPDPDSDEDEDYERER 16 2 H0Y6J6;Q5W012;Q96I25;Q5W011;Q5W010 H0Y6J6 RBM17 Splicing factor 45 1 0 RPDPDS(1)DEDEDYERER;RPDPDS(1)DEDEDYERER ; 167.9 0.00011899 381240000 5567.3 3816.8 4373 4881.3 4314.7 5408.1 4161.4 3984.4 5553.8 4117.9 TRUE FALSE FALSE 5126.64233 4146.707185 4535.067227 4861.102474 4263.250021 4286.399098 4278.157684 5199.225218 4944.562035 4260.996718 1.203155663 0.973177747 1.064320751 1.140836944 1.00052882 1.005961605 1.004027453 1.220189914 1.160423807 1 12.05697523 -7.236407811 24.92260191 1.095934641 1.055492525 0.078178025 0.086165074 2347.359836 2337143.669 0.016501153 0.020202559 5.80E-08 7.236407811 -0.040442116 RPDPIDWSLKYKTPDFESTGLYSAMPR ddPTM_HeLa_Curcumin_4h_R1 1 RPDPIDWSLKYKTPDFESTGLYSAMPR 27 3 H0YMX4;P50440-3;P50440-2;P50440 H0YMX4 GATM "Glycine amidinotransferase, mitochondrial" 0 0 47.648 0.0085203 0 4838.3 3996.1 4004.2 4519.8 4562.1 4635.5 3874 3730.1 4760.6 4122.1 FALSE FALSE TRUE 4455.34345 4341.505078 4152.599174 4501.098265 4507.699937 3674.045047 3982.694014 4867.390319 4238.37409 4265.342668 1.044545256 1.017856106 0.973567541 1.05527237 1.056820117 0.861371602 0.933733658 1.141148718 0.993677278 1 12.05844593 RPDQQLQGEGK ddPTM_HeLa_Curcumin_4h_R1 3 RPDQQLQGEGK 11 1 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 0 ;; ;; 118.77 0.00064941 17548100 9088.7 6956.8 8086.6 9407.1 8949.5 10461.4 8266.1 8539.1 9651.3 8306.3 FALSE FALSE TRUE 8369.319805 7558.114793 8386.29651 9368.175913 8842.783058 8291.587716 8498.024519 11142.63228 8592.576536 8594.943307 0.973749274 0.879367615 0.975724471 1.089963666 1.028835531 0.964705341 0.988723743 1.296417194 0.999724632 1 13.06927241 -6.274765468 23.15112032 0.97663933 1.06045561 0.251500039 0.090780851 391.055224 679371.4603 0.013503983 0.020719054 5.31E-07 6.274765468 0.08381628 RPDQQLQGEGK(ac)IIDR ddPTM_HeLa_Curcumin_4h_R1 1 RPDQQLQGEGKIIDR 15 2 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 1 RPDQQLQGEGK(1)IIDR 126.91 0.00030165 2765700 451.48 416.08 505.06 357.99 473.85 658.04 369.5 542.02 578.86 382.48 FALSE TRUE FALSE 415.7448816 452.0441012 523.7779679 356.5087322 468.1996482 521.5550864 379.8671755 707.2794028 515.3605062 395.7711515 1.050467878 1.142185577 1.32343645 0.900795146 1.183006003 1.317819867 0.959815222 1.787091859 1.302167943 1 8.628522645 -4.255998717 24.97618187 1.070947325 1.787092166 0.593945752 0.155739171 246.0885932 1129671.69 0.019042529 0.221361499 5.55E-05 4.255998717 0.716144841 RPDS(ph)PTRPTLR ddPTM_HeLa_Curcumin_4h_R1 2 RPDSPTRPTLR 11 2 Q7RTP6 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 0 RPDS(0.919)PT(0.04)RPT(0.04)LR;RPDS(0.978)PT(0.011)RPT(0.011)LR ; 109.95 0.0048601 88057400 3744.8 3640.3 3331.5 3829.3 3229.8 4448.7 3431.6 2480.3 4049.7 3855.9 TRUE FALSE FALSE 3448.395129 3954.951311 3454.968321 3813.455371 3191.286744 3525.989473 3527.88146 3236.532052 3605.458042 3989.892238 0.864282773 0.991242639 0.865930234 0.95577904 0.799842841 0.883730503 0.884204698 0.811182824 0.903647975 1 11.96213407 -13.52287875 0.182538656 1.506956127 0.851022885 0.172492751 0.05906524 37.86868519 0.43809518 6.878319915 0.066970559 3.00E-14 13.52287875 -0.655933242 RPDTTESLNSS(ph)LSNGTSDADLFDSHDDRDDDAEAGSVEEHK ddPTM_HeLa_Curcumin_4h_R1 1 RPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHK 41 2 Q96SU4-5;Q96SU4-4;Q96SU4-3;Q96SU4-7;Q96SU4-2;Q96SU4;Q96SU4-6 Q96SU4-5 OSBPL9 Oxysterol-binding protein-related protein 9 1 0 RPDTTES(0.001)LNS(0.113)S(0.329)LS(0.329)NGT(0.113)S(0.113)DADLFDSHDDRDDDAEAGSVEEHK 50.444 0.0010942 12511000 1059.1 1084.7 1041.5 1219.4 1311.2 1496.6 1157.2 554.39 1043 1316.2 TRUE FALSE FALSE 975.2711174 1178.456635 1080.098906 1214.354446 1295.564796 1186.18829 1189.667918 723.4209589 928.5855095 1361.937852 0.716090764 0.865279303 0.793060347 0.891637195 0.951265724 0.870956254 0.873511163 0.531170316 0.681811955 1 10.41144516 -9.537381532 1.298357748 1.000033433 0.811022501 0 0.148247602 0.474197393 1.431229978 0.078707981 0.018734381 2.90E-10 9.537381532 -0.189010933 RPDY(ph)APMESS(ph)DEEDEEFQFIK ddPTM_HeLa_Curcumin_4h_R1 1 RPDYAPMESSDEEDEEFQFIK 21 1 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 2 0 RPDY(0.693)APMES(0.614)S(0.693)DEEDEEFQFIK 71.091 0.0016041 12536000 1264.1 1216.7 1011.9 1203.4 1326.4 1625.7 1053.7 1140.9 1145.4 1115.7 TRUE FALSE FALSE 1164.045151 1321.866126 1049.401904 1198.42065 1310.583546 1288.511495 1083.263986 1488.755158 1019.752486 1154.470492 1.00829355 1.144997759 0.908989802 1.038069538 1.135224811 1.116106045 0.938321069 1.2895567 0.883307536 1 10.17301558 -4.2499607 24.60852795 1.022296649 1.289556897 0.461082512 0.087612138 841.2251568 1803415.995 0.010119903 0.212661064 5.62E-05 4.2499607 0.267260248 RPDYAPMES(ph)S(ph)DEEDEEFQFIKK ddPTM_HeLa_Curcumin_4h_R1 4 RPDYAPMESSDEEDEEFQFIKK 22 2 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 2 0 RPDY(0.372)APMES(0.814)S(0.814)DEEDEEFQFIKK;RPDY(0.284)APMES(0.858)S(0.858)DEEDEEFQFIKK;RPDY(0.005)APMES(0.997)S(0.997)DEEDEEFQFIKK;RPDY(0.284)APMES(0.858)S(0.858)DEEDEEFQFIKK ;;; 67.227 0.003023 217694600 8921.3 7273 7388.75 7774.2 8085.52 9192.2 7563.85 7468.7 9850.2 8124.93 TRUE FALSE FALSE 8215.169691 7901.645712 7662.583575 7742.03242 7989.105455 7285.634103 7776.071274 9745.872248 8769.657704 8407.270713 0.977150608 0.939858604 0.911423438 0.920873454 0.950261473 0.866587309 0.924922194 1.159219511 1.043103999 1 13.03742181 -7.51033444 2.359426873 0.991357399 0.946059385 0.080810509 0.075469593 0.596431022 6.615102469 0.013353062 0.014483045 3.09E-08 7.51033444 -0.045298014 ANVVTTPS(ph)TNR ddPTM_HeLa_Curcumin_4h_R1 1 ANVVTTPSTNR 11 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;E9PDP5 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 0 ANVVT(0.109)T(0.362)PS(0.52)T(0.009)NR 103.14 0.0092454 15225000 4807.1 3836.1 4557.3 4588.5 4893.3 4423.5 3173.7 849.21 3880 3739.4 TRUE FALSE FALSE 4426.612963 4167.675391 4726.197547 4569.514003 4834.950593 3506.016237 3262.74548 1108.13022 3454.373707 3869.343872 1.144021599 1.07710132 1.221446763 1.180953194 1.249553091 0.90610097 0.84322965 0.286387113 0.892754385 1 11.91787323 -4.263611953 1.512759931 1.098164059 9.65E-13 0.831320379 0.110276496 0.304620612 0.630926515 0.014841946 0.49766754 5.45E-05 4.263611953 -1.098164059 down LASVS(ph)ADAEVAR ddPTM_HeLa_Curcumin_4h_R1 1 LASVSADAEVAR 12 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 LAS(0.282)VS(0.718)ADAEVAR 153.75 0.00038477 21843000 1150.8 791.13 999.94 1334 1123.7 1940.5 2747 4643.3 1202.4 1401.5 TRUE FALSE FALSE 1059.712966 859.511752 1036.998656 1328.480261 1110.300611 1538.018426 2824.073427 6059.020795 1070.499728 1450.202021 0.730734719 0.59268415 0.71507186 0.916065653 0.76561789 1.060554601 1.94736553 4.178052925 0.738172829 1 10.50203817 -4.209165628 1.593668314 0.831299174 5.733681343 0.987017818 0.118146254 0.111628618 0.239354985 0.021438317 0.878872319 6.18E-05 4.209165628 4.90238217 up RPELEDSTLR ddPTM_HeLa_Curcumin_4h_R1 4 RPELEDSTLR 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ;;; ;;; 164.33 0.00049598 50285900 7219.34 6658.31 7083.46 6878.08 7063.3 8677.4 6784.7 5568.29 8348.4 6849.05 FALSE FALSE TRUE 6647.921621 7233.824648 7345.979259 6849.620327 6979.074761 6877.609426 6975.060422 7266.035988 7432.601407 7087.053978 0.938037391 1.020709687 1.036534967 0.966497553 0.984763878 0.970446881 0.984197446 1.025254783 1.048757556 1 12.79097032 -7.249584397 24.9809271 0.970739878 0.996448318 0 0.035913041 1227.746043 2587120.384 0.005317017 0.006483343 5.63E-08 7.249584397 0.02570844 RPEPSTLENITDDKYATVSS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 RPEPSTLENITDDKYATVSSPSK 23 2 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 0 RPEPSTLENITDDKY(0.001)AT(0.047)VS(0.431)S(0.489)PS(0.032)K 100.94 1.53E-05 96651000 2019.4 1526 2040.6 2053.5 2283.4 2340.2 1604.3 1103.7 1984.7 1300.5 TRUE FALSE FALSE 1859.562359 1657.90064 2116.226431 2045.003161 2256.171946 1854.816141 1649.31234 1440.213049 1766.983375 1345.692278 1.381862993 1.232005762 1.572593129 1.519666267 1.676588313 1.378336021 1.225623693 1.070239514 1.313066445 1 10.39413283 -9.037324933 0.675731759 0.978603722 1.398600156 0.097709122 0.193890221 0.670568844 0.52163267 0.157822552 0.039918594 9.18E-10 9.037324933 0.419996435 RPES(ph)PSEIS(ph)PIK ddPTM_HeLa_Curcumin_4h_R1 2 RPESPSEISPIK 12 1 Q7Z5K2;Q7Z5K2-2;Q7Z5K2-3 Q7Z5K2 WAPAL Wings apart-like protein homolog 2 0 RPES(0.999)PS(0.001)EIS(1)PIK;RPES(1)PS(0.001)EIS(1)PIK ; 114.54 0.0017315 59003000 10928.7 10319 11541.2 11594.9 13262.1 11485 9241.2 6386.2 10818.1 9241.2 TRUE FALSE FALSE 10063.68186 11210.92838 11968.92702 11546.92338 13103.95812 9102.881537 9500.483201 8333.322982 9631.381496 9562.331012 1.052429774 1.172405386 1.251674619 1.207542738 1.370372779 0.951952147 0.993532141 0.871474013 1.007221093 1 13.22314663 -2.611000826 8.961641275 1.067938706 0.758297779 0 0.148915494 0 0 0.02074594 0 0.002449059 2.611000826 -0.309640927 RPES(ph)PSEIS(ph)PIKGSVR ddPTM_HeLa_Curcumin_4h_R1 1 RPESPSEISPIKGSVR 16 2 Q7Z5K2;Q7Z5K2-2;Q7Z5K2-3 Q7Z5K2 WAPAL Wings apart-like protein homolog 2 0 RPES(0.923)PS(0.077)EIS(0.989)PIKGS(0.01)VR 135.79 0.001076 42979000 12229 10320 10707 11935 10675 14047 8621.5 4777 13539 11411 TRUE FALSE FALSE 11261.06175 11212.01481 11103.81084 11885.61613 10547.7076 11133.49386 8863.396086 6233.485309 12053.80557 11807.5314 0.953718552 0.949564683 0.940400704 1.006613129 0.89330337 0.942914609 0.750656152 0.527924517 1.02085738 1 13.52741975 -4.19660265 1.153289482 0.972469264 0.257517857 0.940732169 0.034904117 0.262872193 0.256752597 0.004762096 0.233961446 6.36E-05 4.19660265 -0.714951407 RPES(ph)PSEISPIK ddPTM_HeLa_Curcumin_4h_R1 1 RPESPSEISPIK 12 1 Q7Z5K2;Q7Z5K2-2;Q7Z5K2-3 Q7Z5K2 WAPAL Wings apart-like protein homolog 1 0 RPES(0.999)PS(0.001)EISPIK 96.756 0.017507 30937000 1962.7 1760.9 1916.6 1791.9 2081.5 2198.5 1613.3 1180 2228.4 1934.8 TRUE FALSE FALSE 1807.350224 1913.10435 1987.630882 1784.485593 2056.679472 1742.506318 1658.564856 1539.776568 1983.950095 2002.034156 0.902756938 0.955580275 0.99280568 0.891336238 1.027294897 0.870367927 0.82843984 0.769106043 0.990967157 1 10.96725087 -4.883983601 2.428528834 0.955589758 0.788373157 0.705192486 0.043493772 0.135353055 1.564150461 0.006689625 0.027846431 1.31E-05 4.883983601 -0.167216601 RPFGTCDPK ddPTM_HeLa_Curcumin_4h_R1 1 RPFGTCDPK 9 1 P09172 P09172 DBH Dopamine beta-hydroxylase;Soluble dopamine beta-hydroxylase 0 0 89.752 0.0073935 0 1503 1510.9 1758.5 1800.4 1880.1 1953.9 1872.5 1684.9 1816 1917.2 FALSE FALSE TRUE 1384.035964 1641.495464 1823.671557 1792.950422 1857.681035 1548.639115 1925.03731 2198.618254 1616.789343 1983.822557 0.697661169 0.827440669 0.91927151 0.903785681 0.936414917 0.780633887 0.970367689 1.108273644 0.814986873 1 10.95406727 -4.460588415 3.464778993 0.861557931 1.101365612 0.469707637 0.082243838 0.23968023 5.218014796 0.016182828 0.111419561 3.46E-05 4.460588415 0.23980768 RPGAPSLS(ph)PAPR ddPTM_HeLa_Curcumin_4h_R1 4 RPGAPSLSPAPR 12 1 Q5QP82-2;Q5QP82 Q5QP82-2 DCAF10 DDB1- and CUL4-associated factor 10 1 0 RPGAPS(0.018)LS(0.982)PAPR;RPGAPS(0.003)LS(0.997)PAPR;RPGAPS(0.119)LS(0.881)PAPR;RPGAPS(0.002)LS(0.998)PAPR ;;; 113.76 0.0010175 18901100 8952.8 6963.8 7631.8 7323.1 7797.5 8604.8 6001.7 6379.5 8874.7 7607 TRUE FALSE FALSE 8244.176433 7565.719842 7914.641222 7292.798953 7704.519905 6820.067484 6170.091549 8324.580182 7901.167613 7871.342684 1.047365966 0.961172718 1.005500782 0.926499994 0.978806312 0.86644271 0.783867734 1.05758071 1.003789052 1 12.94239403 -6.142383717 1.051551184 1.020247684 0.899705918 0.245152025 0.069450829 0.403703199 0.880821764 0.0114097 0.025684384 7.20E-07 6.142383717 -0.120541765 RPGHDDGQRPSGGAAAAPR ddPTM_HeLa_Curcumin_4h_R1 2 RPGHDDGQRPSGGAAAAPR 19 2 Q8N726-2;Q8N726 Q8N726-2 CDKN2A Tumor suppressor ARF 0 0 ; ; 62.813 0.0070024 5970800 1252.6 1216.8 854.19 1051.5 1196.75 1949.71 1006.1 889.13 1374.62 1124.6 FALSE FALSE TRUE 1153.455388 1321.97477 885.8470328 1047.149172 1182.479538 1545.318168 1034.328458 1160.221644 1223.827625 1163.679766 0.991213753 1.136029695 0.7612464 0.899860255 1.016155451 1.327958269 0.888842866 0.997028287 1.051687638 1 10.18447838 -5.514567156 24.88395101 0.980930964 1.072870388 0.090986142 0.137496631 715.2490532 2141369.825 0.019032146 0.039588888 3.06E-06 5.514567156 0.091939424 RPGNSTVT(ph)SSPPVT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 RPGNSTVTSSPPVTPK 16 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 2 0 RPGNS(0.001)T(0.032)VT(0.651)S(0.295)S(0.02)PPVT(1)PK 145.99 0.00020621 8027300 3463.3 2548.9 2882.6 3338.9 3418.2 3313.6 2474.8 1343.6 3152 3266.2 TRUE FALSE FALSE 3189.176151 2769.215558 2989.431692 3325.084516 3377.440197 2626.322008 2544.236227 1753.257455 2806.233486 3379.700207 0.943626936 0.819367219 0.8845257 0.983840078 0.999331299 0.77708727 0.752799382 0.518761235 0.83032024 1 11.72267956 -3.899392837 0.782735382 0.959529174 1.33E-12 0.713729513 0.075376592 1.291668323 0.387179741 0.011166943 1.231498044 0.000126069 3.899392837 -0.959529174 RPILQLS(ph)PPGPR ddPTM_HeLa_Curcumin_4h_R1 1 RPILQLSPPGPR 12 1 Q8N3X1-2;Q8N3X1;F5GXL1 Q8N3X1-2 FNBP4 Formin-binding protein 4 1 0 RPILQLS(1)PPGPR 71.08 0.016745 227340000 2383.1 2335.7 2617.3 2718.5 1970.3 2260.5 2050.7 1689.2 2513 2956.5 TRUE FALSE FALSE 2194.47512 2537.5875 2714.29944 2707.251567 1946.805459 1791.646819 2108.237123 2204.229304 2237.330187 3059.238155 0.717327324 0.829483477 0.887246858 0.884943058 0.636369371 0.585651305 0.689137954 0.72051576 0.731335736 1 11.57895671 -13.52287875 0.162067187 2.012960784 0.655278651 0.046763551 0.118962298 37.90680114 0.408115238 12.2527607 0.186754694 3.00E-14 13.52287875 -1.357682133 RPIS(ph)DDDCPSASK ddPTM_HeLa_Curcumin_4h_R1 1 RPISDDDCPSASK 13 1 Q96PU4 Q96PU4 UHRF2 E3 ubiquitin-protein ligase UHRF2 1 0 RPIS(0.984)DDDCPS(0.016)ASK 163.91 0.00027737 18731000 3820 2997.5 4042.3 3374.7 3430 3657.7 2925.2 1399.2 3100.8 3797.3 TRUE FALSE FALSE 3517.642969 3256.590543 4192.111194 3360.736386 3389.09949 2899.051789 3007.273239 1825.809639 2760.649998 3929.255892 0.895244053 0.82880592 1.066896967 0.855311152 0.862529594 0.737811909 0.765354388 0.464670586 0.702588499 1 11.94004041 -3.848528577 0.580750587 0.949821744 4.89E-13 0.550918583 0.106358577 1.759285612 0.28901574 0.013452722 1.248048257 0.000141733 3.848528577 -0.949821744 GAGATS(ph)GSPPAGRN ddPTM_HeLa_Curcumin_4h_R1 1 GAGATSGSPPAGRN 14 1 B4DEE8;P16455 B4DEE8 MGMT Methylated-DNA--protein-cysteine methyltransferase 1 0 GAGAT(0.125)S(0.781)GS(0.093)PPAGRN 90.793 0.014705 134860000 4331.1 3449.3 3330 3788.2 3746.2 5330.1 3689.6 1497.6 4553.9 3801.5 TRUE FALSE FALSE 3988.288865 3747.442122 3453.412729 3772.525432 3701.529012 4224.577177 3793.120246 1954.211346 4054.348563 3933.601842 1.013902531 0.952674488 0.877926356 0.959051166 0.94100246 1.07397173 0.964286778 0.496799479 1.030696223 1 11.94163522 -4.263458204 5.247868257 0.990127641 0.476458776 0.886608809 0.051711271 0.03584604 3.4035974 0.007329063 0.066129296 5.45E-05 4.263458204 -0.513668864 down RPLDS(ph)PEAEELPAMK ddPTM_HeLa_Curcumin_4h_R1 1 RPLDSPEAEELPAMK 15 1 Q5VWG9 Q5VWG9 TAF3 Transcription initiation factor TFIID subunit 3 1 0 RPLDS(1)PEAEELPAMK 73.722 0.015243 34065000 6216 4466.9 4675.1 5565.2 5824.7 6016.6 5076.9 4727.2 5804.8 4549.3 TRUE FALSE FALSE 5723.997041 4852.998932 4848.363319 5542.172677 5755.244257 4768.689339 5219.34415 6168.501519 5168.027963 4707.387836 1.215960367 1.030932462 1.029947709 1.177335046 1.222598277 1.013022403 1.108755924 1.31038736 1.097854722 1 12.200711 -9.558945747 1.307886444 0.999390994 1.141211594 0.090727172 0.096195205 0.52886187 1.609806984 0.066829277 0.015468518 2.76E-10 9.558945747 0.1418206 RPLEDGDQPDAK ddPTM_HeLa_Curcumin_4h_R1 2 RPLEDGDQPDAK 12 1 Q96AE4;E9PEB5;Q96AE4-2 Q96AE4 FUBP1 Far upstream element-binding protein 1 0 0 ; ; 101.39 0.0049136 0 5807.1 4541.2 4828.1 4877.8 5339.5 6288.8 5222.4 5117 5252.1 5333.9 FALSE FALSE TRUE 5347.461907 4933.721093 5007.033633 4857.616956 5275.82995 4984.431991 5368.926489 6677.149744 4675.95777 5519.252628 0.968874278 0.893911083 0.907194139 0.880122235 0.955895717 0.903099084 0.972763316 1.209792375 0.847208505 1 12.43025721 -4.264325869 5.196580386 0.958238565 1.22035822 0.677751163 0.054854993 0.069622403 6.341245692 0.007220325 0.064925056 5.44E-05 4.264325869 0.262119655 RPLEDGDQPDAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 RPLEDGDQPDAKK 13 2 Q96AE4;E9PEB5;Q96AE4-2 Q96AE4 FUBP1 Far upstream element-binding protein 1 0 1 ; RPLEDGDQPDAK(1)K;RPLEDGDQPDAK(1)K 115.12 0.00021684 6724900 3887.6 3900.6 2989.3 3278.2 3519.1 5073.9 4185.8 4728.8 5343.9 3210.98 FALSE TRUE FALSE 3579.892358 4237.750483 3100.086088 3264.635677 3477.137031 4021.515945 4303.242282 6170.589351 4757.68754 3322.561316 1.077449599 1.275446886 0.933041047 0.982565968 1.046523059 1.210366209 1.295158124 1.857178473 1.431933706 1 11.69808011 -3.721653341 1.041317999 1.044123577 3.444292737 0.666734963 0.152348796 1.14138821 0.44533789 0.013870934 3.991215543 0.000189822 3.721653341 2.40016916 RCAT(ph)PVIIDEILPSKK ddPTM_HeLa_Curcumin_4h_R1 1 RCATPVIIDEILPSKK 16 2 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 0 RCAT(1)PVIIDEILPSKK 74.649 0.0081558 39678000 3861.3 2768.8 2763.2 3163.1 2858.6 4377.2 3038.1 1045.8 3633.8 3036.1 TRUE FALSE FALSE 3555.674031 3008.122734 2865.606623 3150.01193 2824.513062 3469.319379 3123.340909 1364.659606 3235.181231 3141.604249 1.131802019 0.957511671 0.912147551 1.002676238 0.899067113 1.104314581 0.99418662 0.43438304 1.029786369 1 11.61728574 -4.263334313 4.802709056 1.032194446 0.402015947 0.838982065 0.074021704 0.055042868 3.625466099 0.011968066 0.115333195 5.45E-05 4.263334313 -0.630178499 down RPLPVES(ph)PDTQR ddPTM_HeLa_Curcumin_4h_R1 1 RPLPVESPDTQR 12 1 P57682 P57682 KLF3 Krueppel-like factor 3 1 0 RPLPVES(0.835)PDT(0.165)QR 87.138 0.0083733 21964000 1914.4 1337.7 1459.8 1659.7 1753.7 2172.3 1425.9 942.17 1719.4 1185.7 TRUE FALSE FALSE 1762.87322 1453.324827 1513.901472 1652.832601 1732.788273 1721.740493 1465.906916 1229.433296 1530.786122 1226.902987 1.436848096 1.184547469 1.233921091 1.347158348 1.412327048 1.40332244 1.194802631 1.002062355 1.2476831 1 10.26080546 -9.514200029 1.248610794 0.9989736 1.298580901 0.042621571 0.146976585 0.373852067 1.037584013 0.095870215 0.022762526 3.06E-10 9.514200029 0.299607301 RPLS(ph)GPDVGTPQPAGLASGAK ddPTM_HeLa_Curcumin_4h_R1 1 RPLSGPDVGTPQPAGLASGAK 21 1 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 0 RPLS(0.939)GPDVGT(0.061)PQPAGLASGAK 66.925 0.0018353 19001000 1699.3 1073.9 1612.8 1839.7 1683 1912.2 1292.1 603.41 2048 1382.5 TRUE FALSE FALSE 1564.798612 1166.723131 1672.571787 1832.087809 1662.931324 1515.588165 1328.352848 787.3869312 1823.339524 1430.541772 1.093850346 0.815581309 1.16918766 1.28069508 1.162448631 1.059450479 0.928566278 0.550411702 1.274579715 1 10.48234591 -4.279245721 2.300127068 1.063805437 0.435562092 0.603208991 0.133858545 0.288153879 1.825051493 0.017196374 0.357372116 5.26E-05 4.279245721 -0.628243345 RPLS(ph)SSHEASEGQAK ddPTM_HeLa_Curcumin_4h_R1 1 RPLSSSHEASEGQAK 15 1 A0A0J9YVR0;Q8IZ21-3;Q8IZ21;Q8IZ21-2 A0A0J9YVR0;Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 0 RPLS(0.664)S(0.168)S(0.168)HEASEGQAK 73.296 0.011562 14294000 2821.9 2264.2 1839.7 2081.5 3920.4 5268.1 3061.6 1837.9 3326.9 2061.1 TRUE FALSE FALSE 2598.543637 2459.907359 1907.8809 2072.887305 3873.65179 4175.436676 3147.500256 2398.267249 2961.947393 2132.723072 1.21841587 1.15341152 0.894575074 0.971943958 1.816293846 1.95779599 1.475812916 1.124509451 1.388810124 1 11.05848093 -5.767628743 24.99243633 1.084151313 1.611203267 0.492104456 0.242619548 85.21955783 344115.1167 0.034789923 0.064219462 1.71E-06 5.767628743 0.527051954 RPMDGTYGPPAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 RPMDGTYGPPAKR 13 2 O14497;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497 ARID1A AT-rich interactive domain-containing protein 1A 0 1 RPMDGTYGPPAK(1)R 94.547 0.0030731 3422800 319.74 368.35 204.87 320.85 324 404.11 287.24 361.12 305.04 340.45 FALSE TRUE FALSE 294.4322416 400.1885327 212.4626624 319.5224077 320.1365116 320.2930307 295.2991813 471.2238256 271.5778752 352.2806122 0.835788946 1.135993634 0.603106317 0.907011049 0.908754273 0.909198575 0.838249881 1.337637694 0.770913487 1 8.460581268 -4.255796033 24.74807159 0.9069201 1.337637907 0.500886721 0.134804667 332.2326909 1456906.907 0.01701169 0.198967896 5.55E-05 4.255796033 0.430717807 RPMEFEAALLSPGS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 RPMEFEAALLSPGSPK 16 1 B4DQP0;Q9H9L7-2;Q9H9L7 B4DQP0 AKIRIN1 Akirin-1 1 0 RPMEFEAALLSPGS(1)PK 122.16 0.00037752 23336000 2700.1 2048.4 2619.6 2252.1 2740.5 5102 3307.9 1564.7 3112.3 2950.5 TRUE FALSE FALSE 2486.384236 2225.454569 2716.68468 2242.781407 2707.821327 4043.787689 3400.710771 2041.769827 2770.888477 3053.029655 0.81439898 0.728933165 0.889832392 0.734608458 0.886929258 1.324516348 1.113880687 0.668768423 0.907586493 1 11.57602589 -5.469531515 24.99844434 0.879191858 1.053901959 0.183653763 0.169809208 440.4116198 206375.6441 0.024889089 0.055653325 3.39E-06 5.469531515 0.174710102 RPMSS(ph)PEMK ddPTM_HeLa_Curcumin_4h_R1 1 RPMSSPEMK 9 1 P51610-2;P51610;A6NEM2;P51610-4;H7C1C4 P51610-2 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 1 0 RPMS(0.03)S(0.97)PEMK 45.368 0.020221 104260000 4896.3 3987.1 4213.9 4306.1 4160.3 5446.1 3906.8 2094.1 4414 3680.6 TRUE FALSE FALSE 4508.752688 4331.727158 4370.070841 4288.282499 4110.69114 4316.51747 4016.414293 2732.58145 3929.795243 3808.500576 1.183865566 1.137383879 1.1474518 1.125976592 1.079346335 1.133390263 1.054592014 0.717495349 1.031848405 1 11.8950074 -4.26465435 3.616489593 1.101213289 0.675327926 0.828834386 0.052464474 0.110282296 2.601569256 0.009907036 0.125936393 5.44E-05 4.26465435 -0.425885363 RPNEDS(ph)DEDEEK ddPTM_HeLa_Curcumin_4h_R1 4 RPNEDSDEDEEK 12 1 Q12996;H0YE74;E9PLP8 Q12996 CSTF3 Cleavage stimulation factor subunit 3 1 0 RPNEDS(1)DEDEEK;RPNEDS(1)DEDEEK;RPNEDS(1)DEDEEK;RPNEDS(1)DEDEEK ;;; 171.15 0.00019202 51345700 11949.05 12195.71 13707.14 11318.21 13664.84 12969.8 10701.26 9599.42 10599.83 11302.97 TRUE FALSE FALSE 11003.27008 13249.85283 14215.13867 11271.37825 13501.89571 10279.71728 11001.50855 12526.23897 9437.055168 11695.74737 0.940792387 1.132877824 1.215410886 0.963715947 1.154427783 0.878927781 0.940641774 1.071007998 0.806879191 1 13.51369643 -3.67933269 6.735986957 1.00236773 10.99575922 0.026636142 0.121696127 29968.50443 5109.506288 0.014665101 4575755.898 0.000209251 3.67933269 9.993391488 RPNEDS(ph)DEDEEKGAVVPPVHDIYR ddPTM_HeLa_Curcumin_4h_R1 3 RPNEDSDEDEEKGAVVPPVHDIYR 24 2 Q12996;H0YE74;E9PLP8 Q12996 CSTF3 Cleavage stimulation factor subunit 3 1 0 RPNEDS(1)DEDEEKGAVVPPVHDIYR;RPNEDS(1)DEDEEKGAVVPPVHDIYR;RPNEDS(1)DEDEEKGAVVPPVHDIYR ;; 66.906 0.00037906 852805000 8470.88 7274.13 7459.53 7367.8 7390.94 9060.7 7312.05 6843.68 8340.08 8441.91 TRUE FALSE FALSE 7800.40091 7902.873384 7735.986744 7337.313996 7302.807868 7181.408685 7517.206444 8930.286528 7425.19409 8735.265744 0.892978089 0.904708983 0.885604053 0.8399646 0.836014391 0.822116796 0.860558415 1.022325684 0.85002498 1 13.09263588 -8.870229787 0.552118867 1.010202101 0.872919977 0 0.070339035 0.773233991 0.410000853 0.05269748 0.013880754 1.35E-09 8.870229787 -0.137282124 RPPEDDFR ddPTM_HeLa_Curcumin_4h_R1 2 RPPEDDFR 8 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 0 0 ; ; 107.57 0.007698 3828100 1636.72 1475.44 1599.2 1464.19 1812.59 1952.39 1667.74 1191.33 1976.47 1358.39 FALSE FALSE TRUE 1507.171885 1602.970459 1658.467759 1458.13157 1790.976048 1547.442306 1714.532296 1554.561033 1759.656186 1405.593951 1.072266911 1.140422138 1.179905304 1.037377522 1.274177401 1.100917021 1.219792028 1.10598159 1.251895104 1 10.45696417 -7.665137544 0.588577491 1.006234098 1.165055986 0 0.099114987 0.39288327 0.315554138 0.02196535 0.018903372 2.16E-08 7.665137544 0.158821888 RPPEEDWR ddPTM_HeLa_Curcumin_4h_R1 2 RPPEEDWR 8 1 Q8IXT5 Q8IXT5 RBM12B RNA-binding protein 12B 0 0 ; ; 123.35 0.010589 12481200 2875.1 2635.6 2652 2530.4 2591.3 3193.1 2386.7 2098.7 3177 2945 FALSE FALSE TRUE 2647.532801 2863.40952 2750.285453 2519.929875 2560.40044 2530.815066 2453.664379 2738.583969 2828.491048 3047.338531 0.868801669 0.939642738 0.902520486 0.826928105 0.840208731 0.830500137 0.805182737 0.898680583 0.92818406 1 11.57333406 -13.52287875 0.158279933 1.552775751 0.815249557 0.48626269 0.041511852 25.26992476 0.267910832 4.308507127 0.071484592 3.00E-14 13.52287875 -0.737526194 RPPES(ph)PPIVEEWNSR ddPTM_HeLa_Curcumin_4h_R1 2 RPPESPPIVEEWNSR 15 1 A0A3B3IU46;Q9BTL3 A0A3B3IU46 FAM103A1 RNMT-activating mini protein 1 0 RPPES(1)PPIVEEWNSR;RPPES(1)PPIVEEWNSR ; 173.03 6.09E-05 81678000 1031.42 937.02 832.8 766.38 787.84 2117.9 1351.39 1129.15 1072.44 762.05 TRUE FALSE FALSE 949.7820187 1018.011834 863.6643006 763.2089226 778.4455226 1678.623666 1389.306366 1473.422637 954.7960151 788.5311808 1.204495195 1.291022928 1.09528237 0.967886802 0.987209563 2.128798083 1.761891476 1.868566105 1.210853849 1 9.623023994 -5.266416277 24.99519237 1.097294426 1.903965861 0.889168513 0.131240883 94.93732174 476799.4825 0.019740108 0.045467707 5.41E-06 5.266416277 0.806671435 RPPGPT(ph)TSPASTSLSSPGQR ddPTM_HeLa_Curcumin_4h_R1 1 RPPGPTTSPASTSLSSPGQR 20 1 Q01970-2;Q01970 Q01970-2 PLCB3 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3" 1 0 RPPGPT(0.356)T(0.356)S(0.283)PAS(0.003)T(0.001)SLS(0.001)SPGQR 56.719 0.011368 12672000 1521.6 1405.9 1225.1 1620.5 1823.6 920.9 732.74 490.35 1361.6 1107 TRUE FALSE FALSE 1401.163754 1527.419731 1270.503284 1613.7948 1801.854761 729.8949593 753.2987123 639.8554577 1212.235887 1145.468168 1.223223651 1.333445812 1.109156343 1.408851722 1.5730291 0.637202307 0.657633912 0.558597328 1.058288585 1 10.16172165 -5.175848819 9.990368164 1.175747659 0.619810336 0.72902287 0.171406131 0.24794022 27.74161179 0.027414196 0.070015677 6.67E-06 5.175848819 -0.555937323 RPPGPTT(ph)SPASTSLSSPGQR ddPTM_HeLa_Curcumin_4h_R1 2 RPPGPTTSPASTSLSSPGQR 20 1 Q01970-2;Q01970 Q01970-2 PLCB3 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3" 1 0 RPPGPT(0.024)T(0.486)S(0.486)PAS(0.002)T(0.001)SLSSPGQR;RPPGPT(0.152)T(0.714)S(0.124)PAS(0.004)T(0.001)S(0.002)LS(0.002)S(0.001)PGQR ; 63.115 0.006546 11192000 3939.32 3235.55 3735.02 4041.51 4470.72 1474.17 1507.3 1683.89 3597.13 3086.59 TRUE FALSE FALSE 3627.518665 3515.216525 3873.443127 4024.787302 4417.409584 1168.410525 1549.590781 2197.300309 3202.533839 3193.848773 1.135782851 1.100620842 1.212782258 1.260168401 1.383099169 0.365831512 0.48517976 0.68797882 1.00271931 1 11.64108029 -5.25410174 24.99984716 1.113224517 0.510214978 0.823845755 0.135317763 193.2834841 658528.1813 0.020651449 0.051507943 5.57E-06 5.25410174 -0.60300954 RPPS(ph)PDVIVLS(ph)DNEQPS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 RPPSPDVIVLSDNEQPSSPR 20 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 3 0 RPPS(1)PDVIVLS(0.997)DNEQPS(0.556)S(0.447)PR;RPPS(1)PDVIVLS(0.985)DNEQPS(0.553)S(0.462)PR ; 97.784 0.00026885 164620100 4527.6 3829.85 4247.9 4419.8 4497.1 5025.5 4032.52 3280.45 4382.5 4425.95 TRUE FALSE FALSE 4169.235682 4160.885169 4405.330911 4401.512039 4443.47502 3983.154651 4145.661658 4280.644104 3901.750714 4579.751433 0.910362875 0.90853952 0.96191485 0.961080989 0.97024371 0.869731624 0.905215429 0.934689178 0.851956874 1 12.16105358 -9.345421479 0.970390469 1.001831553 0.926930748 0 0.054513188 0.450129744 0.729309944 0.024296203 0.005779147 4.51E-10 9.345421479 -0.074900805 RPPS(ph)PDVIVLS(ph)DNEQPSSPR ddPTM_HeLa_Curcumin_4h_R1 1 RPPSPDVIVLSDNEQPSSPR 20 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 2 0 RPPS(1)PDVIVLS(0.999)DNEQPSSPR 215.32 2.88E-49 0 2472.5 2087.3 2071.6 2352.4 2170.8 2806.7 1793 1408.9 2268.3 1981.9 TRUE FALSE FALSE 2276.799016 2267.716911 2148.375318 2342.666392 2144.914628 2224.558782 1843.306754 1838.467124 2019.473165 2050.770877 1.110216183 1.105787553 1.047594025 1.142334533 1.045906518 1.084742721 0.89883603 0.896476122 0.984738562 1 11.0019506 -4.756920192 24.9901238 1.064368038 0.897655991 0.67696409 0.046282409 50.90730381 281495.4169 0.006975405 0.024428495 1.75E-05 4.756920192 -0.166712047 RPPS(ph)PDVIVLSDNEQPS(ph)S(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 RPPSPDVIVLSDNEQPSSPR 20 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 3 0 RPPS(1)PDVIVLS(0.509)DNEQPS(0.767)S(0.724)PR 79.67 0.0010877 141850000 3810.1 3220 3572.6 3891.3 3518.9 3907 2944.9 2946.9 3894.3 3497.6 TRUE FALSE FALSE 3508.526565 3498.322452 3705.003699 3875.198832 3476.939416 3096.644159 3027.525968 3845.396244 3467.105033 3619.14134 0.969436183 0.966616698 1.023724511 1.070750896 0.960708381 0.855629518 0.836531565 1.062516184 0.957991056 1 11.82143174 -5.515000065 24.98817386 0.993098562 0.909741764 0.232968179 0.064138202 359.3952496 1139863.741 0.008718456 0.018101823 3.05E-06 5.515000065 -0.083356798 RPPS(ph)PDVIVLSDNEQPS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 4 RPPSPDVIVLSDNEQPSSPR 20 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 2 0 RPPS(1)PDVIVLS(0.004)DNEQPS(0.572)S(0.424)PR;RPPS(1)PDVIVLSDNEQPS(0.818)S(0.182)PR;RPPS(1)PDVIVLS(0.016)DNEQPS(0.555)S(0.429)PR;RPPS(1)PDVIVLS(0.037)DNEQPS(0.519)S(0.445)PR ;;; 185.3 8.59E-08 212042400 7183.18 6050.45 6905.92 6744.25 6447.54 8431.37 6453.4 7730.03 7417.32 6026.76 TRUE FALSE FALSE 6614.623723 6573.423938 7161.85947 6716.34408 6370.657297 6682.608821 6634.465036 10086.88056 6603.658553 6236.189461 1.060683574 1.054077009 1.148435197 1.076994874 1.0215625 1.071585279 1.063865214 1.617475002 1.058925261 1 12.60644904 -4.260604217 5.49809141 1.045519934 1.63862924 0.947147163 0.039234352 0.026198184 3.029894919 0.00639741 0.058134482 5.49E-05 4.260604217 0.593109306 RPPS(ph)PDVIVLSDNEQPSSPR ddPTM_HeLa_Curcumin_4h_R1 2 RPPSPDVIVLSDNEQPSSPR 20 1 Q86YP4-2;Q86YP4;Q86YP4-3;C9JMI3;C9JGN4;C9JHD7;C9JJK9 Q86YP4-2 GATAD2A Transcriptional repressor p66-alpha 1 0 RPPS(1)PDVIVLSDNEQPSSPR;RPPS(1)PDVIVLSDNEQPSSPR ; 186.58 5.31E-08 63318300 4208.03 3325.87 3660.92 3512.97 3251.14 4732.5 2986.51 3624.71 4981.6 3543.32 TRUE FALSE FALSE 3874.959985 3613.343383 3796.596916 3498.434261 3212.372279 3750.926154 3070.303433 4729.867393 4435.130943 3666.450106 1.056869689 0.985515493 1.035496681 0.95417479 0.876153278 1.023040283 0.83740494 1.290040027 1.209652611 1 11.84016819 -7.228296947 22.4863547 1.026855139 0.989682541 0.024516775 0.128770652 690.4905315 468480.3715 0.017443045 0.021361739 5.91E-08 7.228296947 -0.037172598 RPPS(ph)PEPSTK ddPTM_HeLa_Curcumin_4h_R1 1 RPPSPEPSTK 10 1 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 RPPS(1)PEPSTK 83.877 0.012678 11335000 4218.5 4175.4 3561.8 4279.8 4041.1 4811 3955.7 3321.6 4672.4 4160.1 TRUE FALSE FALSE 3884.601274 4536.302971 3693.803441 4262.091322 3992.912522 3813.144369 4066.686296 4334.340549 4159.84941 4304.663165 0.902417013 1.053811366 0.858093491 0.990110296 0.927578388 0.88581713 0.944716495 1.006894241 0.966358865 1 12.07168464 -9.607921574 1.392371888 1.000182545 0.939518003 0.042945394 0.056726655 0.664442549 2.300585427 0.03772422 0.008574034 2.47E-10 9.607921574 -0.060664543 RPPSAFFLFCSEYRPK ddPTM_HeLa_Curcumin_4h_R1 2 RPPSAFFLFCSEYRPK 16 2 Q5T7C4;P09429 Q5T7C4 HMGB1 High mobility group protein B1 0 0 ; ; 109.6 0.00060147 4560400 1306.39 948.08 1473.27 988.74 816.49 7424.2 3614.27 3110.37 1633.55 1432.69 FALSE FALSE TRUE 1202.987853 1030.027811 1527.870682 984.6488559 806.75389 5884.337232 3715.676689 4058.707495 1454.353652 1482.475871 0.81147213 0.694802412 1.030620944 0.664192163 0.544193606 3.969263411 2.506399438 2.737789919 0.981030235 1 10.53379291 -5.272039746 24.99997144 0.861491147 3.014675789 0.877994994 0.384476317 153.8314144 362797.032 0.051111178 0.115400385 5.35E-06 5.272039746 2.153184642 RPPTPAPWPSSGLGTPLT(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 1 RPPTPAPWPSSGLGTPLTPPK 21 1 M0R0S1;M0R2P6;Q8TBC3;M0R1G0;M0QZE8;M0R0K4;M0QYB1;M0R0E3;M0R0S2 M0R0S1 SHKBP1 SH3KBP1-binding protein 1 1 0 RPPTPAPWPSSGLGT(0.092)PLT(0.908)PPK 72.585 0.0013731 23023000 1315.5 1390.9 1441.9 1561.1 1664 1902.1 1388.9 680.6 1441.4 1226 TRUE FALSE FALSE 1211.376787 1511.123198 1495.338082 1554.640582 1644.157887 1507.583019 1427.868796 888.1118069 1283.282026 1268.603409 0.954890061 1.19117069 1.178727782 1.225474069 1.296037734 1.188380079 1.125543875 0.700070488 1.011570691 1 10.30902541 -7.26657104 24.70399064 0.978698082 1.143476066 0.144946853 0.153154773 433.6307778 2087508.533 0.02569165 0.029848808 5.41E-08 7.26657104 0.164777984 RPQS(ph)PGAS(ph)PSQAER ddPTM_HeLa_Curcumin_4h_R1 2 RPQSPGASPSQAER 14 1 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 2 0 RPQS(1)PGAS(0.762)PS(0.238)QAER;RPQS(1)PGAS(0.908)PS(0.092)QAER ; 108.97 0.0012804 27326000 5836.2 4898.7 4712.6 5028.5 5677.4 5446.9 4779.4 3037.6 5539 4404 TRUE FALSE FALSE 5374.258612 5322.1218 4887.253102 5007.693399 5609.700713 4317.151541 4913.497101 3963.750257 4931.385558 4557.038672 1.179331359 1.167890418 1.072462503 1.098892013 1.230996951 0.947358987 1.078221506 0.869808343 1.082146963 1 12.1538809 -5.222954654 24.98110334 1.101498778 0.976438769 0.434448734 0.078318172 555.1372983 360348.5188 0.012822375 0.032689979 5.98E-06 5.222954654 -0.12506001 RPQS(ph)PGASPS(ph)QAER ddPTM_HeLa_Curcumin_4h_R1 1 RPQSPGASPSQAER 14 1 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 2 0 RPQS(0.998)PGAS(0.14)PS(0.862)QAER 103.77 0.0060137 10643000 2580.5 2719.1 2250.5 2507.7 2525.6 2529.4 2167.5 1392 2974 2772.4 TRUE FALSE FALSE 2376.250702 2954.126888 2333.90551 2497.323802 2495.48387 2004.773928 2228.314216 1816.414392 2647.759641 2868.740694 0.828325372 1.029764347 0.813564473 0.870529639 0.869888267 0.698834137 0.776756931 0.633174827 0.922969318 1 11.48620185 -2.172041072 0.201749406 0.973950323 1.74E-18 0.654288444 0.06898777 17.05101038 0.297202173 0.074542832 4.808606605 0.00672913 2.172041072 -0.973950323 RPQS(ph)PGASPSQAER ddPTM_HeLa_Curcumin_4h_R1 2 RPQSPGASPSQAER 14 1 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 1 0 RPQS(1)PGASPSQAER;RPQS(1)PGASPSQAER ; 115.58 0.0010112 16332800 1207.84 990.09 1091.06 1029.06 1325.87 1287.2 864.82 1055.87 1243.24 1008.09 TRUE FALSE FALSE 1112.238189 1075.668968 1131.495643 1024.802022 1310.059866 1020.22021 889.0845217 1377.799902 1106.859682 1043.121052 1.066259939 1.031202434 1.084721319 0.982438251 1.255903965 0.978045844 0.852331107 1.320843731 1.061103771 1 10.02669087 RPQYSNPPVQGEVMEGADNQGAGEQGRPVR ddPTM_HeLa_Curcumin_4h_R1 3 RPQYSNPPVQGEVMEGADNQGAGEQGRPVR 30 2 H0Y449;P67809;C9J5V9 H0Y449 YBX1 Nuclease-sensitive element-binding protein 1 0 0 ;; ;; 118.08 2.24E-16 12067400 1844.49 1544.24 1692.55 1755.02 1533.54 1895.1 1306.92 1368.32 1608.4 1548.95 FALSE FALSE TRUE 1698.49667 1677.717225 1755.277392 1747.758192 1515.253537 1502.034898 1343.588658 1785.514469 1431.962544 1602.775897 1.05972187 1.046757209 1.095148358 1.090456997 0.945393264 0.937145923 0.838288534 1.114013801 0.893426552 1 10.646357 -5.74116992 24.65097859 1.039874726 0.948568451 0.144561315 0.082925548 200.6039363 243965.5907 0.00966774 0.019314888 1.81E-06 5.74116992 -0.091306275 RPRPTPGDGEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 RPRPTPGDGEKR 12 3 I3L4Q4;Q9BUL5-4;Q9BUL5;I3L410;I3L1N0;Q9BUL5-3 I3L4Q4 PHF23 PHD finger protein 23 0 1 RPRPTPGDGEK(1)R 66.023 0.018894 819080 202.74 145.34 114.77 144.4 68.579 213.06 132.01 86.216 131.49 156.02 FALSE TRUE FALSE 186.6929151 157.902542 119.0234772 143.8025111 67.76124022 168.8689543 135.7138453 112.5028615 117.065876 161.4416834 1.156410855 0.978077896 0.737253692 0.890739666 0.419725803 1.046005906 0.840636956 0.696863779 0.725127944 1 7.334869313 -6.902521017 4.076482364 1.073793514 0.77720575 0.122050318 0.18968898 0.150533041 4.684950116 0.024785796 0.032921976 1.25E-07 6.902521017 -0.296587764 RPS(ph)ADSESPGTPSPDGAAWEPPAR ddPTM_HeLa_Curcumin_4h_R1 1 RPSADSESPGTPSPDGAAWEPPAR 24 1 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 0 RPS(0.422)ADS(0.315)ES(0.259)PGT(0.004)PSPDGAAWEPPAR 65.782 0.0007725 13429000 923.14 743.43 749.19 895.28 754.1 1131.5 918.26 727.93 1086.4 807.23 TRUE FALSE FALSE 850.0724949 807.6887765 776.9556405 891.5755686 745.10785 896.8141454 944.0239042 949.872506 967.224638 835.2811824 1.017708184 0.966966326 0.930172566 1.067395731 0.892044339 1.073667364 1.130186965 1.13718892 1.157962921 1 9.706118127 -5.01794566 8.175774347 0.996615066 1.126219005 0.359116792 0.069186902 0.090514244 34.85295925 0.006160046 0.016660825 9.60E-06 5.01794566 0.129603939 SMS(ph)DVSAEDVQNLR ddPTM_HeLa_Curcumin_4h_R1 8 SMSDVSAEDVQNLR 14 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424;E9PJ10;E9PK58;E9PLU6 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 S(0.277)MS(0.723)DVSAEDVQNLR;SMS(1)DVSAEDVQNLR;S(0.045)MS(0.955)DVSAEDVQNLR;S(0.004)MS(0.996)DVSAEDVQNLR;S(0.042)MS(0.958)DVSAEDVQNLR;S(0.041)MS(0.957)DVS(0.002)AEDVQNLR;S(0.036)MS(0.963)DVSAEDVQNLR;S(0.013)MS(0.761)DVS(0.226)AEDVQNLR ;;;;;;; 203.85 5.89E-09 527911000 21835.26 19092.28 20678.1 22239.78 23093.94 28355.8 19402.82 5265.71 24991.84 19616.36 TRUE FALSE FALSE 20106.97613 20742.53161 21444.44858 22147.75768 22818.55985 22474.48744 19947.21091 6871.200739 22250.29768 20298.02705 0.99058771 1.021898905 1.056479456 1.091128592 1.124176246 1.107225219 0.982716737 0.338515695 1.096180315 1 14.30905189 -4.263261604 4.886595637 1.024375745 0.303194516 0.939346207 0.054094122 0.032725598 2.310748593 0.008370156 0.07963751 5.45E-05 4.263261604 -0.721181229 down RPS(ph)EGNEPSTK ddPTM_HeLa_Curcumin_4h_R1 2 RPSEGNEPSTK 11 1 F2Z329;A0A087WWU1;Q96Q45-2;Q96Q45;Q96Q45-5;Q96Q45-3 F2Z329 TMEM237 Transmembrane protein 237 1 0 RPS(1)EGNEPSTK;RPS(1)EGNEPSTK ; 87.083 0.0096186 12604700 2966.2 2886.8 3389.8 6025.7 3503.2 6079.7 2850 3263.7 6541.2 4587 TRUE FALSE FALSE 2731.42214 3136.322129 3515.42897 6000.76725 3461.426628 4818.701688 2929.96333 4258.787106 5823.646725 4746.397909 0.575472641 0.660779435 0.740651972 1.264278167 0.72927443 1.0152334 0.617302507 0.897267188 1.226961337 1 12.21261734 RPS(ph)PGEMR ddPTM_HeLa_Curcumin_4h_R1 2 RPSPGEMR 8 1 A0A0G2JHC2;Q6NYC8;Q6NYC8-2;Q6NYC8-3 A0A0G2JHC2 PPP1R18 Phostensin 1 0 RPS(1)PGEMR;RPS(1)PGEMR ; 101.3 0.0066997 34401000 2048.85 1583.79 1823.31 1701.99 1534.38 1656.45 1055.6 1231.22 1605.42 1879.85 TRUE FALSE FALSE 1886.681361 1720.68575 1890.883473 1694.947616 1516.083521 1312.883598 1085.217295 1606.61331 1429.309443 1945.174648 0.969929031 0.884591907 0.972089306 0.871360121 0.779407403 0.674943815 0.557902241 0.825948103 0.734797487 1 10.92568398 -5.794754835 1.372790309 0.978132072 0.670284032 0.419666978 0.103052524 0.129727769 0.489258483 0.010277906 0.025791076 1.60E-06 5.794754835 -0.30784804 RPS(ph)PHDEEEFEVEEAAEAQAEPK ddPTM_HeLa_Curcumin_4h_R1 2 RPSPHDEEEFEVEEAAEAQAEPK 23 1 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 RPS(1)PHDEEEFEVEEAAEAQAEPK;RPS(1)PHDEEEFEVEEAAEAQAEPK ; 147.87 2.80E-06 14219100 5654.2 5253.3 5013.7 4247.9 5059.2 3440.1 2608.4 2916.4 4755.2 4674.9 TRUE FALSE FALSE 5206.664104 5707.371844 5199.512132 4230.323315 4998.872344 2726.584482 2681.584684 3805.596935 4233.566457 4837.352427 1.076345828 1.179854462 1.074867339 0.874512118 1.033390149 0.56365223 0.554349662 0.786710704 0.875182555 1 12.24000193 -5.267295034 24.77951601 1.038294835 0.626848737 0.728436321 0.106090184 128.1027191 542096.5112 0.013447269 0.030839306 5.40E-06 5.267295034 -0.411446099 RPS(ph)PPEPWDEEDGASCSTFFGSEER ddPTM_HeLa_Curcumin_4h_R1 3 RPSPPEPWDEEDGASCSTFFGSEER 25 1 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 0 RPS(0.999)PPEPWDEEDGAS(0.001)CSTFFGSEER;RPS(0.999)PPEPWDEEDGAS(0.001)CSTFFGSEER;RPS(1)PPEPWDEEDGASCSTFFGSEER ;; 87.748 2.67E-05 29029700 2543.93 2506.51 2074.52 2321.24 2598.87 2641.49 1964.79 1432.08 2552.65 1992.9 TRUE FALSE FALSE 2342.575256 2723.161556 2151.403536 2311.635324 2567.880173 2093.615198 2019.916719 1868.7146 2272.630681 2062.153127 1.135985115 1.320542844 1.043280205 1.120981412 1.245242237 1.015256904 0.979518297 0.906195847 1.102066889 1 11.00993575 -4.858584575 3.000794497 1.099098444 0.935330074 0.374705961 0.09430699 0.264274753 4.679211529 0.015123085 0.057606937 1.38E-05 4.858584575 -0.16376837 RPS(ph)PQPSPR ddPTM_HeLa_Curcumin_4h_R1 5 RPSPQPSPR 9 1 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 RPS(1)PQPSPR;RPS(1)PQPSPR;RPS(0.999)PQPS(0.001)PR;RPS(1)PQPSPR;RPS(1)PQPSPR ;;;; 105.25 0.0050072 144128000 2818.65 2941.25 2419.18 3126.12 2349.27 3048.24 1807.41 1550.96 3472.28 3137.1 TRUE FALSE FALSE 2595.550878 3195.478544 2508.836939 3113.184944 2321.25649 2416.000663 1858.12106 2023.840564 3091.379571 3246.113991 0.799587102 0.984401211 0.772873949 0.959049791 0.715087793 0.744274745 0.572413989 0.623465648 0.952332413 1 11.66449795 -3.114715178 0.239497113 0.958995359 2.76E-18 0.68887299 0.081786207 8.802144882 0.25939816 0.061014336 2.745025357 0.000767865 3.114715178 -0.958995359 RPS(ph)PS(ph)SQS(ph)S(ph)SLLTESEQCSLDGK ddPTM_HeLa_Curcumin_4h_R1 1 RPSPSSQSSSLLTESEQCSLDGK 23 1 Q5D1E8 Q5D1E8 ZC3H12A Ribonuclease ZC3H12A 4 0 RPS(0.569)PS(0.702)S(0.702)QS(0.769)S(0.572)S(0.572)LLT(0.053)ES(0.053)EQCS(0.007)LDGK 42.309 0.0081892 0 605.9 472.77 571.56 286.52 574.44 523.69 420.57 511.31 516.97 395.62 TRUE FALSE FALSE 557.9423757 513.6341322 592.7425164 285.3344562 567.5901782 415.0707908 432.3700623 667.2060652 460.2596844 409.3677656 1.362936759 1.254700969 1.447946239 0.697012516 1.386504327 1.0139313 1.056189809 1.629845145 1.124318335 1 8.677253696 -9.568021816 1.370297224 1.001011247 1.233001144 0.060943004 0.249805267 0.763356405 2.587033856 0.161020484 0.038513061 2.70E-10 9.568021816 0.231989897 RPS(ph)QEQSASASSGQPQAPLNR ddPTM_HeLa_Curcumin_4h_R1 6 RPSQEQSASASSGQPQAPLNR 21 1 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 0 RPS(1)QEQSASASSGQPQAPLNR;RPS(0.552)QEQS(0.381)AS(0.029)AS(0.029)S(0.008)GQPQAPLNR;RPS(1)QEQSASASSGQPQAPLNR;RPS(1)QEQSASASSGQPQAPLNR;RPS(0.995)QEQS(0.005)ASASSGQPQAPLNR;RPS(0.965)QEQS(0.035)ASASSGQPQAPLNR ;;;;; 198.6 2.86E-13 178964900 4378.51 4273.6 4779.52 4298.1 5047 5332.01 4447.68 4973.17 4706.59 4425.5 TRUE FALSE FALSE 4031.946313 4642.990941 4956.653216 4280.315601 4986.817821 4226.091022 4572.46993 6489.466639 4190.288852 4579.285796 0.880474924 1.01391159 1.082407484 0.934712484 1.088994669 0.92287121 0.998511588 1.417135101 0.915052923 1 12.16090689 -4.263069923 4.509788582 0.965810609 1.446427948 0.790134513 0.06704194 0.067805277 3.493126967 0.010099575 0.102941235 5.46E-05 4.263069923 0.480617339 RPS(ph)QGPPAR ddPTM_HeLa_Curcumin_4h_R1 1 RPSQGPPAR 9 1 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 RPS(1)QGPPAR 84.821 0.012272 5168400 486.67 407.73 410.53 395.82 327.49 379.62 387.7 587.26 489.04 393.62 TRUE FALSE FALSE 448.149556 442.9723644 425.7446029 394.1822017 323.5848956 300.8825328 398.5778186 766.3128706 435.3935355 407.2982657 1.100298218 1.087587161 1.045289506 0.967797398 0.794466667 0.738727753 0.97858953 1.881453802 1.068979596 1 8.669941861 -4.2603949 24.68523326 1.004610166 1.881454137 0.840433127 0.117790868 24.67736998 583126.9105 0.018627146 0.152495954 5.49E-05 4.2603949 0.876843971 LNHVAAGLVS(ph)PSLKSDTSSK ddPTM_HeLa_Curcumin_4h_R1 1 LNHVAAGLVSPSLKSDTSSK 20 1 Q5T757;Q05519-2;Q05519;Q5T760 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 0 LNHVAAGLVS(0.995)PS(0.002)LKS(0.001)DT(0.001)SSK 72.793 0.0020153 40652000 3486.2 2305.3 2293 2704.7 2172.4 4032.4 3851 6263.1 3781.1 2841.6 TRUE FALSE FALSE 3210.263591 2504.55986 2377.980597 2693.508668 2146.495549 3196.034785 3959.048696 8172.690358 3366.32279 2940.345388 1.091798128 0.851791041 0.808741928 0.916051794 0.730014765 1.086958967 1.346457022 2.779500119 1.144873253 1 11.52176992 -4.208757846 2.153944631 0.983681158 3.422092012 0.948102067 0.12793369 0.13158727 0.603975616 0.019461717 0.645946762 6.18E-05 4.208757846 2.438410854 up TAPAAAVS(ph)PMQR ddPTM_HeLa_Curcumin_4h_R1 5 TAPAAAVSPMQR 12 0 Q5M775-4;Q5M775;J3KSG2 Q5M775-4 SPECC1 Cytospin-B 1 0 TAPAAAVS(1)PMQR;TAPAAAVS(1)PMQR;TAPAAAVS(1)PMQR;TAPAAAVS(1)PMQR;TAPAAAVS(1)PMQR ;;;; 147.73 0.00070269 90015000 20656.3 17484.6 17876.9 17920.7 18240.6 24288.9 16983.9 5939.53 20591.7 17040 TRUE FALSE FALSE 19021.33206 18995.89091 18539.43364 17846.54889 18023.09276 19251.10835 17460.42252 7750.465355 18332.84203 17632.13873 1.078787568 1.077344683 1.051456883 1.01216019 1.022172808 1.091819242 0.990261181 0.439564676 1.039740119 1 14.10591986 -4.2631615 4.193091723 1.041984254 0.392234161 0.975317819 0.028789403 0.027956284 1.098461554 0.004967252 0.054225199 5.46E-05 4.2631615 -0.649750093 down LLES(ph)PGVEAGEGEAEKEEAGAQGR ddPTM_HeLa_Curcumin_4h_R1 2 LLESPGVEAGEGEAEKEEAGAQGR 24 1 A0A0G2JHC2;Q6NYC8;Q6NYC8-3 A0A0G2JHC2 PPP1R18 Phostensin 1 0 LLES(1)PGVEAGEGEAEKEEAGAQGR;LLES(1)PGVEAGEGEAEKEEAGAQGR ; 114.71 3.65E-07 63205000 3080.9 2924.2 3035.6 3070.7 3699.6 4002.5 4594.7 10551.3 3034.1 2488.6 TRUE FALSE FALSE 2837.043514 3176.954818 3148.102006 3057.994257 3655.484686 3172.336383 4723.614916 13768.3428 2701.266821 2575.078665 1.101730814 1.233731172 1.222526538 1.187534307 1.419562337 1.231937659 1.834357521 5.346765901 1.049003612 1 11.33040079 -4.208063511 2.339760801 1.11861035 6.743304242 0.989635845 0.127074319 0.056804517 0.32426561 0.021919897 0.682478116 6.19E-05 4.208063511 5.624693892 up RPS(ph)VDAPVTDVGFLR ddPTM_HeLa_Curcumin_4h_R1 2 RPSVDAPVTDVGFLR 15 1 A0A1B0GTT1;A0A1B0GVM0;Q9BUH8;G3V536;G3V3S3 A0A1B0GTT1 BEGAIN Brain-enriched guanylate kinase-associated protein 1 0 RPS(1)VDAPVTDVGFLR;RPS(1)VDAPVTDVGFLR ; 129.89 0.00033958 14253800 1971.93 1356.73 1619.66 1615.23 1551.93 1913.31 1664.28 833.95 1843.28 1514.26 TRUE FALSE FALSE 1815.84966 1473.999696 1679.686024 1608.546606 1533.424248 1516.467939 1710.975218 1088.217516 1641.076796 1566.880422 1.158894855 0.940722518 1.071993753 1.026591808 0.978647909 0.967826209 1.091962854 0.694512166 1.047352926 1 10.61367937 -4.257414308 24.68862142 1.051318748 0.694511999 0.704562263 0.064340011 162.0549945 993950.2754 0.010785201 0.110612427 5.53E-05 4.257414308 -0.356806749 RPS(ph)VNGEPGSVPPPR ddPTM_HeLa_Curcumin_4h_R1 1 RPSVNGEPGSVPPPR 15 1 Q8N3D4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 0 RPS(1)VNGEPGSVPPPR 139 0.00087359 3443900 702.95 636.66 544.11 499.13 634.29 863.28 887.38 685.08 716.32 829.7 TRUE FALSE FALSE 647.3107658 691.6900535 564.2751952 497.0647323 626.726506 684.2259968 912.2774945 893.9577383 637.7414881 858.5320132 0.753973941 0.805666001 0.657255858 0.578970527 0.729997829 0.796972025 1.062601604 1.041263138 0.742827848 1 9.745728121 -4.759214137 24.99017809 0.822321564 1.05193246 0.431220489 0.117770136 57.71528313 648113.8444 0.021563018 0.073548249 1.74E-05 4.759214137 0.229610896 RPSADSES(ph)PGTPSPDGAAWEPPAR ddPTM_HeLa_Curcumin_4h_R1 1 RPSADSESPGTPSPDGAAWEPPAR 24 1 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 0 RPS(0.082)ADS(0.157)ES(0.759)PGT(0.002)PSPDGAAWEPPAR 75.156 0.00026856 22249000 1445.4 1473.8 1588.2 1444.3 1442 1599.2 1626.2 972.74 1614.4 1415.2 TRUE FALSE FALSE 1330.995065 1601.188705 1647.060089 1438.323869 1424.805092 1267.507893 1671.826795 1269.323948 1437.304359 1464.378095 0.908914897 1.093425742 1.124750565 0.982207993 0.97297624 0.865560539 1.141663346 0.866800694 0.981511786 1 10.51607238 -1.029196082 20.99902657 0.979425124 0.00494192 0 0.095673913 0 0 0.012409087 0 0.093498344 1.029196082 -0.974483204 RPSAS(ph)SPNNNTAAK ddPTM_HeLa_Curcumin_4h_R1 1 RPSASSPNNNTAAK 14 1 O75151;E7ET14;A0A087WW48 O75151 PHF2 Lysine-specific demethylase PHF2 1 0 RPS(0.001)AS(0.83)S(0.169)PNNNTAAK 173.71 0.00030509 3237000 1179.5 870 835 1082.6 828.46 1018 783.92 137.79 1409.1 655.72 TRUE FALSE FALSE 1086.14133 945.1989234 865.9458345 1078.120488 818.5811556 806.8553248 805.9146854 179.8015367 1254.525255 678.5062212 1.600783156 1.393058595 1.276253345 1.588961832 1.206446058 1.189164225 1.187777887 0.26499615 1.848951736 1 9.406218233 -4.220050226 2.638128016 1.307535236 5.09E-15 0.646700858 0.242152814 0.286338571 2.343498987 0.033385166 0.857711671 6.02E-05 4.220050226 -1.307535236 ERSPS(ph)PLRGNVVPSPLPT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 ERSPSPLRGNVVPSPLPTR 19 2 H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9;Q9Y2V2 H3BTK3 CARHSP1 Calcium-regulated heat stable protein 1 2 0 ERS(0.175)PS(0.853)PLRGNVVPS(0.461)PLPT(0.51)R 83.064 0.013775 27864000 2656 2073.3 2177.5 2591.4 2413.5 3759.1 3337.2 7552.7 2635.9 2440 TRUE FALSE FALSE 2445.774797 2252.506814 2258.200066 2580.677473 2384.720589 2979.420286 3430.83285 9855.483462 2346.748365 2524.789818 0.968704317 0.89215617 0.894411111 1.022135567 0.94452242 1.180066659 1.358858795 3.903486694 0.929482663 1 11.30194758 -4.206770566 2.537945739 0.981721213 4.789255948 0.991092952 0.082635612 0.040095479 0.284522814 0.01176294 0.345358573 6.21E-05 4.206770566 3.807534735 up SDS(ph)DYDLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SDSDYDLSPK 10 0 A0A1B0GW84;A0A087WSZ7;Q08499-2;Q08499-10;Q08499-9;Q08499-11;Q08499;A0A1W2PQN6;E9PMG3;Q07343-3;Q07343;Q08499-6;Q08499-7;Q08499-12 A0A1B0GW84;Q08499-6 PDE4D;PDE4B "cAMP-specific 3,5-cyclic phosphodiesterase 4D;cAMP-specific 3,5-cyclic phosphodiesterase 4B" 2 0 S(0.168)DS(0.831)DY(0.001)DLS(1)PK 108.32 0.019878 10740000 7133.7 6159.4 6945.3 5875.5 6610.7 9210.4 9308.1 11609 7210.1 6323 TRUE FALSE FALSE 6569.060118 6691.79109 7202.698928 5851.188738 6531.87172 7300.059217 9569.260235 15148.53066 6419.170069 6542.723779 1.004025287 1.022783678 1.10087162 0.894304717 0.998341355 1.115752317 1.462580503 2.315324805 0.98111586 1 12.67567565 -4.206429598 1.513675539 1.002245487 2.954249801 0.985069961 0.04918843 0.097308411 0.183208297 0.006873673 0.293518006 6.22E-05 4.206429598 1.952004314 up RPTETNPVTSNS(ph)DEECNETVK ddPTM_HeLa_Curcumin_4h_R1 3 RPTETNPVTSNSDEECNETVK 21 1 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6;A0A096LNW1 P46100-5 ATRX Transcriptional regulator ATRX 1 0 RPTETNPVTSNS(1)DEECNETVK;RPTETNPVTS(0.001)NS(0.999)DEECNETVK;RPTETNPVTSNS(1)DEECNETVK ;; 182.62 2.48E-10 261665000 9069.7 8235.2 9003 9359.8 11126.5 10746.3 8637.4 5670 8614.5 7742 TRUE FALSE FALSE 8351.823675 8947.013993 9336.6591 9321.071628 10993.82375 8517.396244 8879.742198 7398.756899 7669.510902 8011.033924 1.042540046 1.116836363 1.165474917 1.163529167 1.372335189 1.063208111 1.108438971 0.923570786 0.957368422 1 12.96777274 -7.313636725 2.097141065 1.01655566 1.141249749 0.23743957 0.106313562 0.360764859 3.001220681 0.019433681 0.022598857 4.86E-08 7.313636725 0.124694089 RPTETNPVTSNS(ph)DEECNETVKEK ddPTM_HeLa_Curcumin_4h_R1 1 RPTETNPVTSNSDEECNETVKEK 23 2 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6;A0A096LNW1 P46100-5 ATRX Transcriptional regulator ATRX 1 0 RPTETNPVT(0.008)S(0.247)NS(0.745)DEECNETVKEK 107.78 1.38E-05 7623900 1034.5 772.88 724.85 933.68 887.87 1069.4 657.51 570.31 948.3 888.68 TRUE FALSE FALSE 952.6182334 839.6843033 751.7135786 929.8166796 877.2827301 847.5943854 675.957961 744.1948936 844.2738625 919.5615639 1.035948294 0.913135494 0.817469551 1.01115218 0.954022835 0.921737509 0.735087228 0.809293171 0.918126524 1 9.844802355 -2.339490454 0.284545736 1.021635572 0.008370733 0.337157994 0.075333881 12.65895563 0.317616075 0.031479929 5.570983413 0.004576248 2.339490454 -1.013264839 RPTPNDDTLDEGVGLVHSNIAT(ph)EHIPSPAK ddPTM_HeLa_Curcumin_4h_R1 1 RPTPNDDTLDEGVGLVHSNIATEHIPSPAK 30 1 Q01581 Q01581 HMGCS1 "Hydroxymethylglutaryl-CoA synthase, cytoplasmic" 1 0 RPTPNDDTLDEGVGLVHS(0.028)NIAT(0.557)EHIPS(0.414)PAK 62.717 0.0078773 81060000 3120 2556.4 2514.3 2770 3155.2 3456.7 2568.4 2161.1 3143.7 2636.1 TRUE FALSE FALSE 2873.048708 2777.363825 2607.48217 2758.538474 3117.576301 2739.741455 2640.462392 2820.009442 2798.843975 2727.704279 1.053284526 1.018205619 0.955925534 1.011304083 1.142930458 1.004412933 0.968016369 1.033839872 1.026080428 1 11.41347153 -9.752001986 1.70437395 0.999996212 1.027734093 0 0.049198049 1.189729754 6.254009013 0.036201151 0.007802001 1.77E-10 9.752001986 0.027737881 RPTPNDDTLDEGVGLVHSNIATEHIPS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 2 RPTPNDDTLDEGVGLVHSNIATEHIPSPAK 30 1 Q01581 Q01581 HMGCS1 "Hydroxymethylglutaryl-CoA synthase, cytoplasmic" 1 0 RPTPNDDTLDEGVGLVHS(0.088)NIAT(0.438)EHIPS(0.475)PAK;RPTPNDDTLDEGVGLVHS(0.212)NIAT(0.212)EHIPS(0.576)PAK ; 98.98 3.40E-08 160496000 4841.1 4474.1 4827.2 4469.7 5146 6405.2 5151.4 3084.5 5857 5240.5 TRUE FALSE FALSE 4457.921827 4860.821268 5006.100278 4451.205566 5084.637311 5076.689319 5295.93442 4024.949851 5214.501753 5422.606985 0.822099377 0.89639933 0.923190689 0.820860811 0.93767395 0.936208236 0.976639914 0.742253654 0.96162266 1 12.4047709 -9.529212995 1.288329959 0.999982432 0.880644094 0.253624966 0.066997126 0.437442268 1.300413024 0.045519514 0.010892412 2.96E-10 9.529212995 -0.119338338 RPTPNDDTLDEGVGLVHSNIATEHIPS(ph)PAKK ddPTM_HeLa_Curcumin_4h_R1 2 RPTPNDDTLDEGVGLVHSNIATEHIPSPAKK 31 2 Q01581 Q01581 HMGCS1 "Hydroxymethylglutaryl-CoA synthase, cytoplasmic" 1 0 RPTPNDDTLDEGVGLVHS(0.096)NIAT(0.383)EHIPS(0.521)PAKK;RPTPNDDTLDEGVGLVHS(0.102)NIAT(0.102)EHIPS(0.795)PAKK ; 53.097 0.0011233 135293000 6824 6261 6789.1 6315.2 6616.1 8408.8 6800.4 3826.1 7431.6 6397.6 TRUE FALSE FALSE 6283.873199 6802.172942 7040.710018 6289.069376 6537.207329 6664.720093 6991.200922 4992.660277 6616.372073 6619.916124 0.949237586 1.02753159 1.063564838 0.950022517 0.987506066 1.006768057 1.056086028 0.754187845 0.999464638 1 12.69259722 -4.251354845 24.83451687 0.989935115 0.754187704 0.7847553 0.038654167 497.8061156 1225887.961 0.005754658 0.104179408 5.61E-05 4.251354845 -0.235747411 RPTSNGVVSS(ph)PNSTSRPTLPVK ddPTM_HeLa_Curcumin_4h_R1 1 RPTSNGVVSSPNSTSRPTLPVK 22 2 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 0 RPT(0.001)S(0.001)NGVVS(0.423)S(0.53)PNS(0.027)T(0.005)S(0.006)RPT(0.007)LPVK 51.966 0.016829 31733000 580.53 629.99 531.39 523.08 639.45 748.36 748.69 230.38 590.45 437.36 TRUE FALSE FALSE 534.5804379 684.4435284 551.0837809 520.9156336 631.8249764 593.1417002 769.6962264 300.6218015 525.6791122 452.5582274 1.181241232 1.51238777 1.217708015 1.151046654 1.396118639 1.310641735 1.700767282 0.664272094 1.161572325 1 8.821959615 -8.164660764 0.971294292 1.030189489 1.292703898 0.064939102 0.259803268 0.600512802 1.195503738 0.071371742 0.050822578 6.84E-09 8.164660764 0.262514408 RPWEEDFR ddPTM_HeLa_Curcumin_4h_R1 1 RPWEEDFR 8 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 0 0 104.01 0.019114 6954300 4257.7 3030.6 3767 3261.5 3346 4569.9 2870.8 2591.3 3938.3 3187.4 FALSE FALSE TRUE 3920.698552 3292.55156 3906.608334 3248.004777 3306.101135 3622.051227 2951.346922 3381.375441 3506.278343 3298.161913 1.188752601 0.998298946 1.184480458 0.984792397 1.002407166 1.098202976 0.894845978 1.025230274 1.063100732 1 11.68744651 -6.212449353 24.99872161 1.089640603 1.000660664 0.242313433 0.075809412 493.6931288 251922.6737 0.013259751 0.021988781 6.13E-07 6.212449353 -0.08897994 RPWRPEEAVEDPDEEDEDNT(ph)SEAENGFSLEEVLR ddPTM_HeLa_Curcumin_4h_R1 2 RPWRPEEAVEDPDEEDEDNTSEAENGFSLEEVLR 34 2 Q03701 Q03701 CEBPZ CCAAT/enhancer-binding protein zeta 1 0 RPWRPEEAVEDPDEEDEDNT(0.496)S(0.496)EAENGFS(0.008)LEEVLR;RPWRPEEAVEDPDEEDEDNT(0.881)S(0.119)EAENGFSLEEVLR ; 112.35 7.75E-15 23450000 3294.2 2634.4 2754.1 2822.6 3184.8 3495.5 2592.4 2490.5 3614.6 2562.4 TRUE FALSE FALSE 3033.460594 2862.105797 2856.169369 2810.920829 3146.82334 2770.493898 2665.135767 3249.841985 3218.087423 2651.443209 1.144079037 1.079452046 1.077213104 1.060147477 1.186834147 1.044900335 1.00516419 1.225687948 1.213711616 1 11.37256213 -9.478256966 1.186640128 0.999330285 1.102300617 0 0.091333983 0.507975702 1.266409494 0.043177064 0.010303493 3.32E-10 9.478256966 0.102970332 RQAPGVGAVGGGS(ph)PEREEVGAGY(ph)NSEDEYEAAAAR ddPTM_HeLa_Curcumin_4h_R1 1 RQAPGVGAVGGGSPEREEVGAGYNSEDEYEAAAAR 35 2 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74;H7BZQ3 A0A087WXV6 OTUD5 OTU domain-containing protein 5 2 0 RQAPGVGAVGGGS(0.994)PEREEVGAGY(0.654)NS(0.34)EDEY(0.013)EAAAAR 49.567 0.0028172 13849000 1125.3 683.24 691.56 756.52 800 1005.5 593.42 492.5 884.75 827.12 TRUE FALSE FALSE 1036.231318 742.2962211 717.189822 753.3897207 790.4605225 796.9479657 610.0697681 642.6609828 787.6951385 855.8623584 1.210745288 0.867307942 0.83797332 0.880269722 0.923583699 0.931163706 0.712812945 0.750892917 0.92035259 1 9.741234988 -7.181945409 7.055784302 1.099339791 0.844987581 0.439304833 0.097905816 0.139535793 10.74050404 0.017087724 0.020948333 6.58E-08 7.181945409 -0.25435221 RQAPGVGAVGGGS(ph)PEREEVGAGYNS(ph)EDEYEAAAAR ddPTM_HeLa_Curcumin_4h_R1 1 RQAPGVGAVGGGSPEREEVGAGYNSEDEYEAAAAR 35 2 A0A087WXV6;Q96G74-2;Q96G74-3;Q96G74-5;Q96G74;H7BZQ3 A0A087WXV6 OTUD5 OTU domain-containing protein 5 2 0 RQAPGVGAVGGGS(0.699)PEREEVGAGY(0.34)NS(0.885)EDEY(0.076)EAAAAR 55.632 0.00037152 14375000 605.96 592.43 429.51 623.56 826.96 739.3 554.91 614.62 704.34 587.98 TRUE FALSE FALSE 557.9976266 643.6370094 445.4280184 620.9798739 817.0990421 585.9608464 570.4792811 802.0148086 627.0756642 608.4122612 0.917137379 1.057896184 0.732115453 1.020656409 1.34300226 0.963098352 0.937652506 1.318209477 1.030675586 1 9.248905418 -5.99381016 24.99920737 0.949764686 1.121893585 0.274018833 0.146897239 173.1264361 699205.8073 0.02026734 0.036667582 1.01E-06 5.99381016 0.172128899 RQDEDYDEQVEESLQDEDDNDVYILTK ddPTM_HeLa_Curcumin_4h_R1 1 RQDEDYDEQVEESLQDEDDNDVYILTK 27 1 H0Y8C6;O00410-2;O00410;O00410-3 H0Y8C6 IPO5 Importin-5 0 0 94.403 6.67E-06 21718000 2361.2 2115.8 2521.4 2388.3 2512.1 2004.7 2023.3 2159.6 2530.7 2140.3 FALSE FALSE TRUE 2174.308528 2298.680324 2614.845302 2378.417847 2482.144848 1588.902622 2080.068353 2818.052098 2253.088541 2214.675266 0.981773067 1.037931095 1.180690164 1.073935256 1.120771468 0.717442709 0.939220474 1.272444833 1.01734488 1 11.11287946 -4.253234678 24.12675985 1.00021099 1.272445057 0.31159595 0.117591224 593.2965343 1744581.88 0.016209775 0.238980569 5.58E-05 4.253234678 0.272234067 RQDPQVVS(ph)PFSR ddPTM_HeLa_Curcumin_4h_R1 1 RQDPQVVSPFSR 12 1 Q12986-3;Q12986-2;Q12986 Q12986-3 NFX1 Transcriptional repressor NF-X1 1 0 RQDPQVVS(0.648)PFS(0.352)R 91.789 0.0065111 17394000 1634.8 1287.7 1346 1652.3 1643.8 2036.6 1667.3 1018.6 1618.9 1571.8 TRUE FALSE FALSE 1505.403855 1399.00305 1395.883944 1645.46322 1624.198759 1614.186203 1714.079951 1329.166451 1441.31072 1626.419933 0.925593584 0.86017333 0.858255556 1.011708715 0.998634317 0.992478123 1.05389753 0.817234482 0.886186089 1 10.66748409 RQDS(ph)MEALQMDR ddPTM_HeLa_Curcumin_4h_R1 2 RQDSMEALQMDR 12 1 Q8TDR0-2;Q8TDR0 Q8TDR0-2 TRAF3IP1 TRAF3-interacting protein 1 1 0 RQDS(1)MEALQMDR;RQDS(1)MEALQMDR ; 162.67 0.00024061 18662000 6200.4 5550.1 5467.5 5876.6 5642 6849 5024.1 4097.6 6515.1 5789.9 TRUE FALSE FALSE 5709.631797 6029.825913 5670.13036 5852.284186 5574.722835 5428.440196 5165.062724 5346.939377 5800.40983 5991.098594 0.953019168 1.006464143 0.946425813 0.976829891 0.930500934 0.90608427 0.862122805 0.892480618 0.968171319 1 12.54860486 -5.405435306 1.30867468 0.978174275 0.874907218 0.809983121 0.019379371 0.158072573 0.506909302 0.00339833 0.012250768 3.93E-06 5.405435306 -0.103267057 RQDSDLVQCGVTS(ph)PSSAEATGK ddPTM_HeLa_Curcumin_4h_R1 1 RQDSDLVQCGVTSPSSAEATGK 22 1 Q9HC52 Q9HC52 CBX8 Chromobox protein homolog 8 1 0 RQDSDLVQCGVT(0.032)S(0.869)PS(0.052)S(0.047)AEATGK 112.06 9.14E-06 38575000 1093.4 907.36 1248.1 1175.7 1598 1767 1499.1 1299.8 1393.3 1000.7 TRUE FALSE FALSE 1006.856236 985.7881553 1294.355684 1170.835265 1578.944894 1400.504282 1541.160711 1696.103036 1240.458476 1035.474251 0.972362409 0.952016098 1.25001243 1.130723689 1.524851915 1.352524489 1.488362179 1.637996344 1.197961683 1 10.01607596 -5.943007279 0.847413815 0.979976012 1.552405007 0.747750769 0.116572572 0.152069067 0.208484538 0.015772178 0.047072845 1.14E-06 5.943007279 0.572428995 SNVSSPATPT(ph)ASSSSSTTPT(ph)RK ddPTM_HeLa_Curcumin_4h_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 S(0.004)NVS(0.039)S(0.099)PAT(0.44)PT(0.395)AS(0.058)S(0.036)S(0.036)S(0.089)S(0.224)T(0.202)T(0.182)PT(0.196)RK 56.767 0.0048683 47705000 3491.1 2489.1 2598 3013.2 2701.9 4115 2844.7 874.45 2934.2 2927.8 TRUE FALSE FALSE 3214.775751 2704.246713 2694.284165 3000.732177 2669.681607 3261.502614 2924.514626 1141.06578 2612.325601 3029.540832 1.061142902 0.892625933 0.889337466 0.990490752 0.881216579 1.076566647 0.965332632 0.376646443 0.862284335 1 11.56488343 -4.263015955 5.047591257 0.999717013 0.347447294 0.81324046 0.08147505 0.042750697 3.446353555 0.010390504 0.096778218 5.46E-05 4.263015955 -0.652269718 down RQEELENGTAWSLSSESSDDS(ph)SSPQLSGTAR ddPTM_HeLa_Curcumin_4h_R1 1 RQEELENGTAWSLSSESSDDSSSPQLSGTAR 31 1 H3BMG9;H3BSV5;A0A0A0MTL6;Q6ZS17-2;Q6ZS17;Q6ZS17-3;Q6ZS17-4 H3BMG9 FAM65A Protein FAM65A 1 0 RQEELENGT(0.003)AWS(0.006)LS(0.013)S(0.027)ES(0.153)S(0.123)DDS(0.268)S(0.268)S(0.123)PQLS(0.011)GT(0.005)AR 41.846 0.015619 6495200 612.06 513.41 596.8 586.65 602.39 579.66 471.12 272.13 364.26 452.04 TRUE FALSE FALSE 563.6148052 557.7868727 618.917933 584.2225977 595.2068927 459.4319819 484.3383592 355.1011843 324.3015893 467.7483564 1.204953043 1.192493496 1.323185693 1.249010477 1.27249382 0.982220409 1.035467795 0.759171421 0.693324915 1 8.869588774 -4.191057235 1.341898046 1.141985307 0.563011954 0.271007425 0.175530163 1.12366406 1.547773811 0.019185608 0.921302607 6.44E-05 4.191057235 -0.578973353 RQEHLS(ph)RFS(ph)MPDLS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 RQEHLSRFSMPDLSK 15 2 A0A1X7SBR1;Q7Z3G6 A0A1X7SBR1 PRICKLE2 Prickle-like protein 2 3 0 RQEHLS(1)RFS(1)MPDLS(1)K 66.568 0.015783 8261600 1388 1277.1 1387.2 1348.5 1205.3 1534.4 1355.9 1280.9 1356.7 1191.8 TRUE FALSE FALSE 1278.138335 1387.486833 1438.610852 1342.920264 1190.927585 1216.148144 1393.942905 1671.440513 1207.873404 1233.214961 1.036427854 1.125097308 1.166553194 1.088958784 0.965709647 0.986160712 1.130332463 1.355352121 0.979450819 1 10.26820858 -4.333831196 2.842394537 1.035920412 1.387315064 0.684311907 0.063596766 0.156888825 1.894388922 0.00958633 0.116040634 4.64E-05 4.333831196 0.351394652 RQELEAELAK ddPTM_HeLa_Curcumin_4h_R1 1 RQELEAELAK 10 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 107.85 0.0017233 2854600 3260.1 2448.3 2752.3 2400.4 3122.2 3826.2 2499.3 2641.3 3508.4 2974.8 FALSE FALSE TRUE 3002.059645 2659.920143 2854.302659 2390.467781 3084.969804 3032.60299 2569.423631 3446.620211 3123.537298 3078.174079 0.975272863 0.864122715 0.927271358 0.776586288 1.002207713 0.985195415 0.834723302 1.119696327 1.014737054 1 11.58785911 -7.476873406 12.05115181 0.989105976 0.924804903 0.100444268 0.0906468 2.200197247 574.7365615 0.014392989 0.016273173 3.34E-08 7.476873406 -0.064301072 RQEQPSIEST(ph)SPISR ddPTM_HeLa_Curcumin_4h_R1 2 RQEQPSIESTSPISR 15 1 Q5T5P2;Q5T5P2-3 Q5T5P2 KIAA1217 Sickle tail protein homolog 1 0 RQEQPSIES(0.024)T(0.77)S(0.206)PISR;RQEQPSIES(0.03)T(0.871)S(0.1)PISR ; 180.56 0.00055454 17811000 7075.9 6089.8 6055.4 6132 6457.7 7774.3 4979.7 3371.7 7271.4 6637.4 TRUE FALSE FALSE 6515.835049 6616.175176 6279.818451 6106.627409 6380.696145 6161.822546 5119.41698 4399.715809 6473.745612 6868.049156 0.948717008 0.963326707 0.914352578 0.889135658 0.929040547 0.897172167 0.745396089 0.640606336 0.942588713 1 12.74568465 -3.443665729 0.524968457 0.974018169 2.95E-24 0.916552039 0.03014254 1.607263436 0.160946681 0.006347147 1.167064743 0.000360026 3.443665729 -0.974018169 RQFS(ph)APNLK ddPTM_HeLa_Curcumin_4h_R1 1 RQFSAPNLK 9 1 O60333-3 O60333-3 KIF1B Kinesin-like protein KIF1B 1 0 RQFS(1)APNLK 83.226 0.013245 114790000 4176.1 3308.8 3614.6 3560.7 4243.4 5414.8 4338.6 3975.7 4424.5 4173.2 TRUE FALSE FALSE 3845.557278 3594.797928 3748.560256 3545.966767 4192.800226 4291.709443 4460.329439 5187.872628 3939.14342 4318.218389 0.890542564 0.83247247 0.868080286 0.821164297 0.97095604 0.993861138 1.032909649 1.201391908 0.912214961 1 12.07622049 -4.193342985 1.140864323 0.924336541 1.359215126 0.723706734 0.056847554 1.00403264 0.952178403 0.010831979 0.539525673 6.41E-05 4.193342985 0.434878585 RQGIFT(ph)SSPQCPILS(ph)HSGQT(ph)PLGR ddPTM_HeLa_Curcumin_4h_R1 1 RQGIFTSSPQCPILSHSGQTPLGR 24 1 Q13495-3 Q13495-3 3 0 RQGIFT(0.333)S(0.333)S(0.333)PQCPILS(0.728)HS(0.297)GQT(0.975)PLGR 52.273 0.005577 6633100 655.38 422.58 524.29 641.28 565.67 611 384.52 304.2 663.32 445.19 TRUE FALSE FALSE 603.5059814 459.1059322 543.7206486 638.6265533 558.9247547 484.2717126 395.3085963 396.9491796 590.5554555 460.6603194 1.310088923 0.996625741 1.180307106 1.386328552 1.213312133 1.05125554 0.858134681 0.861696054 1.281975961 1 8.847559521 -4.89926833 3.189830311 1.162536263 0.855998669 0.54350098 0.119900825 0.18033039 3.605353796 0.020371758 0.072655284 1.26E-05 4.89926833 -0.306537594 RQGS(ph)FSEDVISHK ddPTM_HeLa_Curcumin_4h_R1 1 RQGSFSEDVISHK 13 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;E9PNZ4 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 1 0 RQGS(0.716)FS(0.284)EDVISHK 72.583 0.014998 20311000 4757 4243 4387.9 4729 4863.3 5946.2 4240.5 4209.6 5413 4608 TRUE FALSE FALSE 4380.47843 4609.746014 4550.519434 4709.432651 4805.308324 4712.891093 4359.477017 5493.087661 4819.207443 4768.127657 0.918699906 0.966783263 0.954361913 0.987690135 1.00779775 0.98841546 0.914295365 1.15204291 1.010712755 1 12.21920715 -4.251694067 24.77741417 0.964994642 1.152043025 0.722134161 0.033228187 501.1466885 1274133.978 0.005059953 0.087892055 5.60E-05 4.251694067 0.187048383 RQHS(ph)RPRPPVS(ph)S(ph)T(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 RQHSRPRPPVSSTK 14 3 Q53F19;Q53F19-2 Q53F19 C17orf85 Uncharacterized protein C17orf85 4 0 RQHS(1)RPRPPVS(1)S(1)T(1)K 49.35 0.009438 0 2134 1196.4 1871 2231.9 1836.7 2222.9 1830.7 1235.3 2640.8 1758 TRUE FALSE FALSE 1965.091648 1299.811485 1940.340906 2222.664989 1814.798552 1761.845483 1882.064515 1611.937283 2351.110847 1819.090369 1.080260597 0.714539259 1.066654488 1.221855179 0.99764068 0.968531038 1.034618481 0.886122708 1.292465117 1 10.8290015 -3.472183459 1.532343899 1.024990692 2.15E-12 0.079362043 0.147210336 21.28645672 7.37516856 0.01722768 59.09014088 0.000337145 3.472183459 -1.024990692 RQLAELETEDGMQES(ph)P ddPTM_HeLa_Curcumin_4h_R1 3 RQLAELETEDGMQESP 16 1 Q96QG7-2;Q96QG7 Q96QG7-2 MTMR9 Myotubularin-related protein 9 1 0 RQLAELETEDGMQES(1)P;RQLAELETEDGMQES(1)P;RQLAELETEDGMQES(1)P ;; 171.11 0.00017389 39173000 5639.1 4578.3 4892.3 5182.8 4887.8 6622.5 4834.9 4808.4 5730.4 5374.5 TRUE FALSE FALSE 5192.759285 4974.027851 5073.612942 5161.354947 4829.516177 5248.918849 4970.554282 6274.459025 5101.789457 5561.263475 0.933737326 0.894406078 0.912312996 0.928090347 0.868420674 0.943835672 0.893781477 1.128243438 0.917379563 1 12.44119697 -8.968099437 0.916060293 0.997687449 0.932443833 0 0.072201744 0.873163907 1.396577408 0.034568004 0.01243958 1.08E-09 8.968099437 -0.065243616 RQLEEAEEEAQR ddPTM_HeLa_Curcumin_4h_R1 2 RQLEEAEEEAQR 12 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ; ; 187.62 2.39E-05 25713000 4716.5 3903.3 4026.4 4687.9 4534.3 5005.8 3993.8 3898.8 4591.8 5012.1 FALSE FALSE TRUE 4343.184048 4240.683859 4175.621926 4668.502712 4480.231434 3967.540653 4105.855279 5087.526172 4088.091028 5186.270102 0.837438846 0.817675087 0.805130054 0.900165749 0.863863884 0.765008489 0.791677872 0.980960512 0.788252626 1 12.34048163 -9.120565353 0.766252267 1.006109762 0.840435118 0 0.087261772 0.454829982 0.4588674 0.045550053 0.011651744 7.58E-10 9.120565353 -0.165674644 RQLEEAEEESQR ddPTM_HeLa_Curcumin_4h_R1 4 RQLEEAEEESQR 12 1 P35749-4;P35749-3;P35749;P35749-2 P35749-4 MYH11 Myosin-11 0 0 ;;; ;;; 247.13 1.00E-26 132969000 9652.4 8155.9 7752.4 8716.6 9105.2 10781.7 8686.9 7586.9 11423 8888.4 FALSE FALSE TRUE 8888.402355 8860.859654 8039.710764 8680.533019 8996.626437 8545.453885 8930.631034 9900.110884 10169.92548 9197.271238 0.966417334 0.963422674 0.874140879 0.943816138 0.978184312 0.929129267 0.97100877 1.07641828 1.105754654 1 13.16699017 -2.943449282 22.1426176 0.97286836 0.965512147 0 0.064640768 0 0 0.006545209 0 0.001139071 2.943449282 -0.007356213 RQLHLEGASLELS(ph)DDDTESK ddPTM_HeLa_Curcumin_4h_R1 2 RQLHLEGASLELSDDDTESK 20 1 P35580;P35580-5;P35580-2;P35580-3;P35580-4 P35580 MYH10 Myosin-10 1 0 RQLHLEGASLELS(0.76)DDDT(0.219)ES(0.021)K;RQLHLEGASLELS(0.995)DDDT(0.005)ESK ; 135.86 4.72E-05 45642300 3307.2 3066.4 3059 2651.7 3780.4 4582.6 3467.6 2648.1 4078.9 3308.2 TRUE FALSE FALSE 3045.43163 3331.445952 3172.369231 2640.727968 3735.321199 3632.117103 3564.891523 3455.4935 3631.454875 3423.159704 0.889655141 0.973207867 0.926737139 0.771429964 1.091191041 1.061042259 1.0414038 1.0094456 1.060848803 1 11.74111289 -5.662216206 22.38063854 0.935784614 1.050838994 0.365460728 0.073436575 4.909188756 1099.360541 0.009910687 0.019821369 2.18E-06 5.662216206 0.11505438 RQPEESESK(ac)TK ddPTM_HeLa_Curcumin_4h_R1 2 RQPEESESKTK 11 2 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;P18583-8 P18583-10 SON Protein SON 0 1 ; RQPEESESK(1)TK;RQPEESESK(1)TK 102.97 0.001675 993890 357.89 355.22 361.39 367.24 499 541.72 429.43 338.53 575.85 440.18 FALSE TRUE FALSE 329.5626289 385.923634 374.7834313 365.7204582 493.0497509 429.3611656 441.47865 441.7462386 512.6806957 455.4762222 0.723556166 0.847296994 0.822838631 0.802940835 1.082492843 0.942664281 0.96926827 0.969855762 1.125592667 1 8.831231931 -5.773389965 24.98356348 0.856528666 0.986055443 0.138239455 0.112463457 237.3373369 496171.069 0.01613179 0.029405828 1.69E-06 5.773389965 0.129526777 RQQEELLAEENQR ddPTM_HeLa_Curcumin_4h_R1 1 RQQEELLAEENQR 13 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 122.1 0.0011318 0 1278.6 1321.5 1050.7 1401.4 1328.6 1688.5 1271.2 1130.6 1240.2 1305.3 FALSE FALSE TRUE 1177.397461 1435.724572 1089.639866 1395.601378 1312.757313 1338.286067 1306.866451 1475.314735 1104.153163 1350.659078 0.871720688 1.062980729 0.806746783 1.033274348 0.971938318 0.990839279 0.967576846 1.092292466 0.817492127 1 10.39944785 -1.000000003 0.640075057 0.944342353 12.22679232 0.237359747 0.081825548 216.3585346 1.34221158 0.012490315 3458.736651 0.099999999 1.000000003 11.28244997 RQS(ph)GLYDSQNPPTVNNCAQDR ddPTM_HeLa_Curcumin_4h_R1 1 RQSGLYDSQNPPTVNNCAQDR 21 1 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 0 RQS(1)GLYDSQNPPTVNNCAQDR 116.7 5.93E-06 9157100 881.51 702.87 730.03 782.18 886.67 1671.3 1369.3 740.56 849.37 464.45 TRUE FALSE FALSE 811.7375533 763.6229509 757.085554 778.9435464 876.0970394 1324.653541 1407.718873 966.3533349 756.196236 480.5896029 1.689045182 1.588929403 1.575326535 1.620808152 1.822962948 2.756309193 2.929149661 2.010766211 1.573476062 1 8.908661627 -1 0.118593105 0.639017873 7.077866718 0.54821621 0.370176089 40.64559678 0.332438815 1.631103085 43.35128923 0.1 1 6.438848845 RQS(ph)LELQK ddPTM_HeLa_Curcumin_4h_R1 4 RQSLELQK 8 1 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 0 RQS(1)LELQK;RQS(1)LELQK;RQS(1)LELQK;RQS(1)LELQK ;;; 109.39 0.0053777 28903300 14868.5 11609.4 13277.2 15482.6 15391.6 19281.1 14949.4 8898.8 16203.8 12563 TRUE FALSE FALSE 13691.64254 12612.86481 13769.26471 15418.5371 15208.06522 15281.98252 15368.83993 11612.00315 14426.28368 12999.56331 1.053238651 0.970252962 1.059209789 1.186081158 1.169890469 1.175576606 1.18225817 0.893261018 1.109751407 1 13.66617554 -6.484204479 7.372701202 1.021368706 1.129983172 0.178032198 0.088028754 0.240817203 38.97376778 0.012361694 0.018718423 3.28E-07 6.484204479 0.108614465 RQS(ph)LPAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 RQSLPASPR 9 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 0 RQS(1)LPAS(1)PR 72.496 0.017287 11101000 2793.3 2228.6 2123.8 2652.1 2646.7 3758.6 2882.7 650.85 3058.2 1998.4 TRUE FALSE FALSE 2572.207358 2421.230254 2202.509896 2641.126313 2615.139831 2979.023992 2963.580804 849.2911689 2722.723111 2067.844251 1.243907686 1.170895851 1.065123689 1.277236577 1.264669633 1.440642345 1.43317409 0.410713316 1.316696414 1 11.01391181 -9.394754312 1.017196743 0.995318679 1.190333914 0 0.292715292 1.37455627 2.444729995 0.200928426 0.046603255 4.03E-10 9.394754312 0.195015235 RQS(ph)PEPSPVTLGR ddPTM_HeLa_Curcumin_4h_R1 2 RQSPEPSPVTLGR 13 1 Q9NRL2;Q9NRL2-2 Q9NRL2 BAZ1A Bromodomain adjacent to zinc finger domain protein 1A 1 0 RQS(0.999)PEPS(0.001)PVTLGR;RQS(0.997)PEPS(0.003)PVTLGR ; 158.52 0.00048629 81495000 4886.5 3873 4458.8 5216.1 4285.7 4993.1 3898.9 1928.25 4986.8 4450.2 TRUE FALSE FALSE 4499.728369 4207.764862 4624.04705 5194.51716 4234.595827 3957.474776 4008.292641 2516.164548 4439.760516 4604.844119 0.977172789 0.913769229 1.004170159 1.128054941 0.919595912 0.859415579 0.87045132 0.546416878 0.964150013 1 12.1689366 -3.872593483 0.988229183 0.990109579 2.85E-19 0.81452753 0.062065119 1.10013882 0.492686275 0.009276933 1.387802906 0.000134093 3.872593483 -0.990109579 T(ph)PTSSPAS(ph)SPLVAK ddPTM_HeLa_Curcumin_4h_R1 1 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 2 0 T(0.982)PT(0.009)S(0.002)S(0.026)PAS(0.899)S(0.082)PLVAK 134.02 0.00027808 0 3454.3 3479.4 3319.5 3347 3357.9 4657.8 3200.3 955.03 4593.7 3359.9 TRUE FALSE FALSE 3180.88851 3780.143832 3442.52359 3333.151001 3317.859236 3691.719776 3290.091805 1246.214251 4089.782603 3476.656275 0.914927522 1.087292943 0.990182324 0.958723192 0.95432478 1.061859293 0.946337959 0.358451958 1.176355176 1 11.76348472 -4.262919611 5.3086018 0.976203884 0.333707749 0.851342466 0.080665734 0.029068103 2.898462512 0.007520764 0.067787553 5.46E-05 4.262919611 -0.642496135 down RQS(ph)SGSATNVASTPDNR ddPTM_HeLa_Curcumin_4h_R1 2 RQSSGSATNVASTPDNR 17 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 0 RQS(0.971)S(0.029)GSATNVASTPDNR;RQS(0.794)S(0.192)GS(0.013)AT(0.001)NVASTPDNR ; 237.16 2.00E-23 11442300 2242.01 1967.38 2011.09 2278.08 1853.42 2165.13 1381.01 1979.92 2280.94 1905.47 TRUE FALSE FALSE 2064.552543 2137.431561 2085.622765 2268.653909 1831.319177 1716.057632 1419.757424 2583.588494 2030.726589 1971.684941 1.04710063 1.084063441 1.057787034 1.150616846 0.928809233 0.870350834 0.720073169 1.310345502 1.029944768 1 10.94521332 -5.656700081 22.76709453 1.038946603 0.934213719 0.091034856 0.144209947 9.389190508 2014.320094 0.019228274 0.038456538 2.20E-06 5.656700081 -0.104732884 RQS(ph)STPSAPELGQQPDVNISEWK ddPTM_HeLa_Curcumin_4h_R1 1 RQSSTPSAPELGQQPDVNISEWK 23 1 I3L213;Q93100-4;Q93100-2;Q93100-3;Q93100 I3L213 PHKB Phosphorylase b kinase regulatory subunit beta 1 0 RQS(0.474)S(0.474)T(0.039)PS(0.013)APELGQQPDVNISEWK 76.208 0.00042139 8190200 2491.1 2058.5 1534.7 2215 1648.5 1658 1632.4 1316.9 1840.7 1540.4 TRUE FALSE FALSE 2293.926806 2236.427568 1591.577332 2205.834917 1628.842714 1314.11211 1678.200751 1718.416748 1638.779815 1593.928785 1.439165179 1.403091272 0.998524744 1.383898037 1.021904322 0.824448446 1.052870596 1.078101333 1.028138666 1 10.63837146 -5.610000612 8.179887034 1.221930238 0.980667083 0.28099657 0.16796686 0.273050034 22.54639887 0.02885101 0.057825251 2.45E-06 5.610000612 -0.241263155 RQS(ph)VGDFVSGALNK ddPTM_HeLa_Curcumin_4h_R1 2 RQSVGDFVSGALNK 14 1 Q6P4F7-3;Q6P4F7;H3BR51;Q6P4F7-2 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 0 RQS(0.992)VGDFVS(0.008)GALNK;RQS(1)VGDFVSGALNK ; 96.805 0.0025507 17431000 8045.8 6076.3 7092 7371.8 7229.8 9613.9 6550.4 3148.8 8859.2 7533.6 TRUE FALSE FALSE 7408.96644 6601.508297 7354.835759 7341.297445 7143.589357 7619.868769 6734.186595 4108.854625 7887.367925 7795.392039 0.950428972 0.846847505 0.943485039 0.941748331 0.916386157 0.977483715 0.863867598 0.527087618 1.01179875 1 12.92840586 -4.260695791 2.509149479 0.957781539 0.431677072 0.888082475 0.044645714 0.124538961 0.96882753 0.006727851 0.139358457 5.49E-05 4.260695791 -0.526104468 RQS(ph)VSGLHR ddPTM_HeLa_Curcumin_4h_R1 1 RQSVSGLHR 9 1 Q8N1G4;J3KRP5 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 1 0 RQS(0.976)VS(0.024)GLHR 72.152 0.020003 5386100 939.81 745.88 1028.6 957.36 980.28 1638 667.55 531.95 914.35 1009.1 TRUE FALSE FALSE 865.4230468 810.3505436 1066.720821 953.398698 968.5908012 1298.260336 686.2796564 694.1391062 814.0480926 1044.16615 0.828817374 0.776074329 1.021600653 0.913071831 0.927621338 1.243346508 0.657251393 0.664778404 0.779615479 1 10.02813558 -13.52287266 0.014925353 2.019680628 3.29E-10 0 0.171040713 12935.65097 15.59391167 1301.613919 853.1909611 3.00E-14 13.52287266 -2.019680628 RQSSGS(ph)ATNVASTPDNR ddPTM_HeLa_Curcumin_4h_R1 1 RQSSGSATNVASTPDNR 17 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 0 RQS(0.037)S(0.105)GS(0.845)AT(0.013)NVASTPDNR 107.83 0.00061891 2349100 1091.1 1088.7 1152.9 1081.4 986.48 1176.8 979.54 786.5 987.3 1165.1 TRUE FALSE FALSE 1004.738284 1182.802377 1195.627488 1076.925453 974.7168703 932.7184147 1007.023256 1026.300229 878.9956601 1205.587138 0.833401628 0.981100693 0.991738756 0.893278818 0.808499725 0.773663209 0.835296947 0.851286644 0.729101723 1 10.23552022 -5.882849325 4.224165509 0.930011971 0.815586221 0.195945616 0.080409828 0.180912566 5.797158988 0.010360904 0.01935965 1.31E-06 5.882849325 -0.11442575 RQSSGSATNVAS(ph)TPDNR ddPTM_HeLa_Curcumin_4h_R1 1 RQSSGSATNVASTPDNR 17 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 0 RQSSGSATNVAS(0.572)T(0.428)PDNR 72.801 0.0077171 696720 201.87 225.21 311.66 276.73 56.474 169.08 207.73 0 185.42 257.51 TRUE FALSE FALSE 185.8917765 244.6761489 323.2103938 275.5849646 55.80058443 134.0109021 213.5583447 0 165.0798899 266.4584533 0.697638878 0.91825253 1.212986076 1.03425116 0.209415703 0.502933573 0.80146958 0 0.619533319 1 8.057766793 -5.766783959 24.99989531 0.899691839 0.417561395 0.523915807 0.248663692 85.72541134 400992.8889 0.035829154 0.066345127 1.71E-06 5.766783959 -0.482130444 RQVDQLTNDK ddPTM_HeLa_Curcumin_4h_R1 2 RQVDQLTNDK 10 1 P08670;B0YJC4 P08670 VIM Vimentin 0 0 ; ; 153.54 4.36E-09 10080800 8505.3 6499.8 7189.6 7088.4 7576.7 9069 7360.7 7498.7 7926.2 7083.5 FALSE FALSE TRUE 7832.09653 7061.613749 7456.052901 7059.070079 7486.352801 7187.987171 7567.221432 9785.01911 7056.71569 7329.651098 1.068549707 0.96343109 1.017245269 0.963084052 1.021379149 0.980672487 1.03241223 1.334991118 0.962762838 1 12.83952881 -4.262570744 5.375909844 1.018125089 1.347239462 0.879829264 0.036574054 0.039158324 4.121488603 0.005268407 0.04731487 5.46E-05 4.262570744 0.329114374 RQVSAS(ph)ELHTSGILGPETLR ddPTM_HeLa_Curcumin_4h_R1 1 RQVSASELHTSGILGPETLR 20 1 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 1 0 RQVS(0.419)AS(0.522)ELHT(0.053)S(0.006)GILGPETLR 57.009 0.020015 23346000 1051.3 783.59 732.63 784.68 559.87 1880.2 1275.3 859.45 1329.4 970.59 TRUE FALSE FALSE 968.0884957 851.320028 759.7819123 781.4332021 553.1939159 1490.225326 1311.081486 1121.492349 1183.568146 1004.31793 0.963926329 0.847659892 0.756515332 0.778073535 0.550815533 1.483818302 1.305444667 1.116670643 1.178479553 1 9.972000331 -5.243797621 24.99827551 0.914079135 1.302324545 0.538046564 0.180800384 525.820112 745083.0943 0.024823399 0.063134642 5.70E-06 5.243797621 0.38824541 RRCEPVLK ddPTM_HeLa_Curcumin_4h_R1 2 RRCEPVLK 8 2 Q9ULV1 Q9ULV1 FZD4 Frizzled-4 0 0 ; ; 114.78 0.0069062 0 7358.6 5223.9 6555.6 7143.4 6066.9 7340.1 5157.1 4725.1 7452.9 6582.5 FALSE FALSE TRUE 6776.159045 5675.430639 6798.556303 7113.842504 5994.55618 5817.68052 5301.794346 6165.761238 6635.335516 6811.241385 0.994849347 0.833244679 0.998137626 1.044426721 0.880097451 0.854129254 0.77838885 0.905233112 0.974174184 1 12.73370205 -5.60712842 5.317164392 0.986627216 0.843268965 0.488956699 0.059751277 0.115135799 5.474832398 0.008692057 0.0176749 2.47E-06 5.60712842 -0.143358251 RRDEDMLYS(ph)PELAQR ddPTM_HeLa_Curcumin_4h_R1 2 RRDEDMLYSPELAQR 15 2 Q9Y2W2 Q9Y2W2 WBP11 WW domain-binding protein 11 1 0 RRDEDMLYS(1)PELAQR;RRDEDMLY(0.134)S(0.866)PELAQR ; 92.096 0.0019385 86645000 5716.7 5233.7 5166.2 5234.7 4701.4 5734.7 5352.3 4257.4 5908.1 5214.9 TRUE FALSE FALSE 5264.217163 5686.077707 5357.663917 5213.040198 4645.338876 4545.258577 5502.471133 5555.461661 5259.996211 5396.117387 0.975556458 1.053734991 0.992873863 0.966072423 0.860866905 0.842320181 1.019709309 1.029529431 0.974774238 1 12.39770602 -5.997516252 24.99703761 0.993750526 0.934140394 0.19099493 0.058779373 109.2046247 1099035.473 0.009028269 0.016292945 1.01E-06 5.997516252 -0.059610132 LPSGS(ph)GAAS(ph)PTGSAVDIR ddPTM_HeLa_Curcumin_4h_R1 1 LPSGSGAASPTGSAVDIR 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 LPS(0.028)GS(0.972)GAAS(0.988)PT(0.011)GSAVDIR 115.53 0.001119 212560000 1084 1004.2 1055.5 1134.3 1205.2 1423.1 1180.7 1663.1 1378 1046.9 TRUE FALSE FALSE 998.2002562 1090.998573 1094.617759 1129.606567 1190.828777 1127.933018 1213.827264 2170.171534 1226.836848 1083.279697 0.921461243 1.007125469 1.010466421 1.042765382 1.099280989 1.041220491 1.120511413 2.003334448 1.132520854 1 10.08119007 -4.205920364 2.529810891 0.988054316 2.314102786 0.947596556 0.067459006 0.087697694 0.615453582 0.008868388 0.26272559 6.22E-05 4.205920364 1.326048471 up RREDS(ph)YHVR ddPTM_HeLa_Curcumin_4h_R1 2 RREDSYHVR 9 2 B1AVT0;P49760-2;P49760-3;P49760 B1AVT0 CLK2 Dual specificity protein kinase CLK2 1 0 RREDS(0.998)Y(0.002)HVR;RREDS(1)YHVR ; 77.124 0.010522 5522200 1320.93 1045.97 1459.47 1278.24 1672.02 1656.75 1316.52 1117.09 1606.53 1622.07 TRUE FALSE FALSE 1216.376997 1136.378986 1513.559242 1272.950982 1652.082254 1313.121375 1353.458008 1457.685599 1430.297678 1678.436812 0.724708245 0.677046034 0.901767187 0.758414599 0.984298153 0.782347816 0.806380078 0.868478091 0.852160575 1 10.71290251 -9.468277217 1.233050764 0.998965363 0.804989813 0.114961972 0.094991759 0.359364437 0.985640253 0.057977576 0.01460361 3.40E-10 9.468277217 -0.19397555 RREEEGLQLR ddPTM_HeLa_Curcumin_4h_R1 1 RREEEGLQLR 10 2 C9J352;C9JWD9;F2Z3G4;C9J4U1;C9JYI4;P52294 C9J352 KPNA1 "Importin subunit alpha-5;Importin subunit alpha-5, N-terminally processed" 0 0 133.13 0.00095431 5267900 1653.6 1348 1683.8 1503.8 1366.7 1838.1 1505.3 1582.3 1852.9 1310.3 FALSE FALSE TRUE 1522.715815 1464.515113 1746.203109 1497.577674 1350.402995 1456.85734 1547.534667 2064.735986 1649.641506 1355.832827 1.123085224 1.080159061 1.287919184 1.104544486 0.995995205 1.074511039 1.141390469 1.522854399 1.216699782 1 10.40496359 -4.253889213 3.034228712 1.07732749 1.598704561 0.642769103 0.089038881 0.164582988 2.195020885 0.01213116 0.207832276 5.57E-05 4.253889213 0.521377072 RREEGPPPPS(ph)PDGAS(ph)SDAEPEPPSGR ddPTM_HeLa_Curcumin_4h_R1 2 RREEGPPPPSPDGASSDAEPEPPSGR 26 2 C9JWF0;C9IYK2;C9JJ64;C9JR83;Q9NTJ3-2;Q9NTJ3;F8WCB7;E9PD53 C9JWF0 SMC4 Structural maintenance of chromosomes protein 4;Structural maintenance of chromosomes protein 2 0 RREEGPPPPS(0.995)PDGAS(0.575)S(0.396)DAEPEPPS(0.034)GR;RREEGPPPPS(0.993)PDGAS(0.739)S(0.267)DAEPEPPSGR ; 56.211 0.0029672 64593000 3285.9 2456.7 2503.6 2533.4 2575.1 3412.9 2207.4 2478.8 2819.6 2801.4 TRUE FALSE FALSE 3025.817548 2669.046201 2596.385618 2522.917462 2544.393614 2705.026069 2269.333703 3234.574709 2510.296934 2898.748441 1.043835852 0.920758132 0.895691941 0.870347156 0.877755923 0.93317034 0.782866726 1.11585216 0.865993371 1 11.50121442 -7.189471994 5.317366987 1.02064918 0.904785766 0 0.093394626 0.180015869 9.53588217 0.012014516 0.014717147 6.46E-08 7.189471994 -0.115863414 RREEGPPPPSPDGASS(ph)DAEPEPPSGR ddPTM_HeLa_Curcumin_4h_R1 1 RREEGPPPPSPDGASSDAEPEPPSGR 26 2 C9JWF0;C9IYK2;C9JJ64;C9JR83;Q9NTJ3-2;Q9NTJ3;F8WCB7;E9PD53 C9JWF0 SMC4 Structural maintenance of chromosomes protein 4;Structural maintenance of chromosomes protein 1 0 RREEGPPPPSPDGAS(0.481)S(0.519)DAEPEPPSGR 56.461 0.0017875 74065000 774.15 679.3 793.32 1073.8 825.98 793.96 729.2 643.03 1169.3 926.42 TRUE FALSE FALSE 712.8752106 738.0156651 822.7211371 1069.3569 816.130728 629.2837462 749.6593895 839.0868869 1041.030715 958.613026 0.743652748 0.769878611 0.858241141 1.115525109 0.851366199 0.656452321 0.782025039 0.875313462 1.085975975 1 9.904804734 -9.499542927 1.255499434 0.999696657 0.823155611 0.321592755 0.117504212 0.562817978 1.592058271 0.084527392 0.020656534 3.17E-10 9.499542927 -0.176541046 RREMT(ph)SFQAGDQEGSLEDIS(ph)KTSVANK ddPTM_HeLa_Curcumin_4h_R1 1 RREMTSFQAGDQEGSLEDISKTSVANK 27 3 A0A1B0GTW6 A0A1B0GTW6 2 0 RREMT(0.464)S(0.464)FQAGDQEGS(0.074)LEDIS(0.36)KT(0.319)S(0.319)VANK 40.404 0.0089153 0 342.26 263.88 432.57 281.52 249.15 378.67 504.83 200.78 354.21 257.85 TRUE FALSE FALSE 315.1697598 286.6886114 448.6014247 280.3551448 246.179049 300.1295735 518.9941711 261.9968977 315.3540492 266.8102683 1.181250489 1.074503666 1.681349925 1.050765949 0.922674568 1.124880146 1.94518065 0.981959575 1.181941202 1 8.05967038 -13.12072987 0.061938362 2.25E-11 1.698623797 0.025269528 0.311221037 436.6433754 2.284110017 68.63771045 13.72385489 7.57E-14 13.12072987 1.698623797 RREY(ph)PDGT(ph)VK ddPTM_HeLa_Curcumin_4h_R1 1 RREYPDGTVK 10 2 Q9HC77 Q9HC77 CENPJ Centromere protein J 2 0 RREY(1)PDGT(1)VK 98.156 0.0056958 76107000 6704.5 6035.6 6528.1 7059.9 7243.1 7559.1 6586.1 4844.6 6380.3 5086.8 TRUE FALSE FALSE 6173.83175 6557.29037 6770.037129 7030.688004 7156.730763 5991.257451 6770.88824 6321.696238 5680.397053 5263.565921 1.172937101 1.24578859 1.286207341 1.335727169 1.359673436 1.138250673 1.28636904 1.201029175 1.079191776 1 12.3618248 -8.19921456 0.67565206 1.014033818 1.271227378 0.645565877 0.064928034 0.250914168 0.251751047 0.02835567 0.016545645 6.32E-09 8.19921456 0.25719356 RREYQLS(ph)DS(ph)T(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 RREYQLSDSTK 11 2 B1AM21;P50148 B1AM21 GNAQ Guanine nucleotide-binding protein G(q) subunit alpha 3 0 RREY(0.001)QLS(1)DS(1)T(1)K 72.607 0.0082132 0 1443.3 1571.1 1836 1540.7 1355.4 1576.2 1514.1 990.11 1538.5 1952.4 TRUE FALSE FALSE 1329.061282 1706.898883 1904.043775 1534.324992 1339.23774 1249.278353 1556.581571 1291.989981 1369.730399 2020.245755 0.657871093 0.844896656 0.942481265 0.759474429 0.66290833 0.618379397 0.770491198 0.639521196 0.67800187 1 10.98031509 -9.443667808 0.944333268 1.01568671 0.734863117 0 0.137539467 0.45642382 0.659176928 0.09489835 0.018928336 3.60E-10 9.443667808 -0.280823593 RRGDS(ph)ES(ph)EEDEQDSEEVR ddPTM_HeLa_Curcumin_4h_R1 3 RRGDSESEEDEQDSEEVR 18 2 Q9NZ63 Q9NZ63 C9orf78 Uncharacterized protein C9orf78 2 0 RRGDS(1)ES(1)EEDEQDSEEVR;RRGDS(1)ES(1)EEDEQDSEEVR;RRGDS(1)ES(1)EEDEQDSEEVR ;; 89.511 0.0022347 59850000 5341.2 5033.13 4571.01 5193.8 5468.86 6677.1 5180.7 5275.68 6222.3 5465.14 TRUE FALSE FALSE 4918.438384 5468.17133 4740.415652 5172.309432 5403.647416 5292.194194 5326.056499 6884.210546 5539.729257 5655.053208 0.869742194 0.966953118 0.838261901 0.914634972 0.955543161 0.935834553 0.941822526 1.217355574 0.97960692 1 12.46532488 -4.260901015 5.423792897 0.931715506 1.228352961 0.770141777 0.046528578 0.063546885 6.931067503 0.007641176 0.069702982 5.48E-05 4.260901015 0.296637455 RRGS(ph)S(ph)GSVDETLFALPAASEPVIR ddPTM_HeLa_Curcumin_4h_R1 1 RRGSSGSVDETLFALPAASEPVIR 24 2 Q9NQC3-5;Q9NQC3 Q9NQC3-5 RTN4 Reticulon-4 2 0 RRGS(0.665)S(0.665)GS(0.665)VDET(0.005)LFALPAASEPVIR 64.749 0.0017845 9827000 1243.9 941.47 1144 1431.7 1069.3 1533 1746.1 1123.9 1601.1 1237.4 TRUE FALSE FALSE 1145.444002 1022.846472 1186.397646 1425.776005 1056.549296 1215.03852 1795.090867 1466.571936 1425.463336 1280.399558 0.894598874 0.798849441 0.926583924 1.113539907 0.825171556 0.948952623 1.401977106 1.145401783 1.113295711 1 10.32237837 -4.776818598 24.76196437 0.939396692 1.27368938 0.55294128 0.114986174 81.97651059 131990.492 0.013765115 0.041518564 1.67E-05 4.776818598 0.334292688 RRGS(ph)SGSVDETLFALPAASEPVIR ddPTM_HeLa_Curcumin_4h_R1 1 RRGSSGSVDETLFALPAASEPVIR 24 2 Q9NQC3-5;Q9NQC3 Q9NQC3-5 RTN4 Reticulon-4 1 0 RRGS(0.332)S(0.332)GS(0.332)VDET(0.004)LFALPAASEPVIR 68.676 0.00033346 3624100 1081.5 716.14 969.43 1044.4 850.78 1072 1220.1 1048.5 1366.4 1097.5 TRUE FALSE FALSE 995.8981338 778.0399505 1005.357929 1040.07855 840.6350042 849.6551161 1254.332722 1368.182823 1216.509339 1135.638043 0.87695031 0.685112616 0.885280248 0.915853916 0.740231458 0.748174228 1.104518055 1.204770157 1.07121221 1 10.14928737 -4.59522409 6.161694781 0.89198455 1.181137767 0.50087218 0.114876165 0.120956472 7.686690348 0.016443825 0.063898684 2.54E-05 4.59522409 0.289153216 RRKEDEVEEWQHR ddPTM_HeLa_Curcumin_4h_R1 1 RRKEDEVEEWQHR 13 3 E7EQR4;P15311 E7EQR4 EZR Ezrin 0 0 48.115 0.016774 21766000 3136.7 2059.7 1994.4 2685.5 2231.3 2830.7 2505.9 2512.5 3591.3 2810.1 FALSE FALSE TRUE 2888.426885 2237.73129 2068.314218 2674.388113 2204.693205 2243.580911 2576.20881 3278.549684 3197.343375 2907.750766 0.993354355 0.769574654 0.711310695 0.919744616 0.758212578 0.771586388 0.885979926 1.127520874 1.099593339 1 11.5056879 -7.282220022 22.15065832 0.996861822 0.841485531 0.327755644 0.11594538 170.1382689 181354.3126 0.018788849 0.021506541 5.22E-08 7.282220022 -0.155376291 RRNDLDDPER ddPTM_HeLa_Curcumin_4h_R1 1 RRNDLDDPER 10 2 Q15393 Q15393 SF3B3 Splicing factor 3B subunit 3 0 0 65.278 0.019298 12495000 1317.4 952.6 967.41 1191.4 1211.8 1212.3 1231.1 1098 1285.6 1344.9 FALSE FALSE TRUE 1213.1264 1034.938499 1003.263066 1186.470302 1197.350076 960.8553146 1265.641353 1432.775145 1144.572896 1391.635175 0.871727319 0.743685211 0.720923906 0.852572803 0.860390782 0.690450581 0.909463468 1.029562324 0.822466202 1 10.44256533 -8.449623456 0.948794422 0.983963857 0.828056891 0 0.10699476 0.445832516 0.827743748 0.034703995 0.020181187 3.55E-09 8.449623456 -0.155906966 RRQSS(ph)S(ph)SANSQQGSPPTK ddPTM_HeLa_Curcumin_4h_R1 1 RRQSSSSANSQQGSPPTK 18 2 Q8WXF8-2 Q8WXF8-2 2 0 RRQS(0.186)S(0.813)S(0.998)S(0.002)ANS(0.001)QQGSPPTK 102.15 0.0015365 0 752.07 1051.1 1122.2 1140.2 1114.7 1083 907.97 1344.3 1120.8 1154.7 TRUE FALSE FALSE 692.5428659 1141.9524 1163.789719 1135.482155 1101.407931 858.3735921 933.4451945 1754.170882 997.8510441 1194.825739 0.579618302 0.955748075 0.974024647 0.950332854 0.9218147 0.718409023 0.78123961 1.468139515 0.835143579 1 10.22258451 -7.115949365 20.38518761 0.799702515 0.948311072 0.10642865 0.210293659 10.49741077 1813.780289 0.038945636 0.047698548 7.66E-08 7.115949365 0.148608557 RRS(ph)PPADAIPK ddPTM_HeLa_Curcumin_4h_R1 1 RRSPPADAIPK 11 2 M0R1Q8;C9JRH2;C9J3R0;C9JMJ4;C9JQZ4;C9JW69;P18754;P18754-2 M0R1Q8 RCC1 Regulator of chromosome condensation 1 0 RRS(1)PPADAIPK 88.706 0.013589 370660000 11425 9066.7 9784 10357 10444 12019 10030 9205.8 10693 9760 TRUE FALSE FALSE 10520.69919 9850.385148 10146.60365 10314.14548 10319.46212 9526.123918 10311.41481 12012.60604 9520.004653 10099.15927 1.0417401 0.975366848 1.004697854 1.021287535 1.021813979 0.943259103 1.021017149 1.189465946 0.942653185 1 13.30194758 -4.265244106 5.558683257 1.011098365 1.195383156 0.726754488 0.034494379 0.048917206 5.968199762 0.004001421 0.034106616 5.43E-05 4.265244106 0.18428479 RRS(ph)PPPGPDGHAK ddPTM_HeLa_Curcumin_4h_R1 1 RRSPPPGPDGHAK 13 2 P57081-3;P57081-2;P57081 P57081-3 WDR4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 1 0 RRS(1)PPPGPDGHAK 50.387 0.019496 34967000 2296.7 1981.4 2404.1 2516 2495.5 2687.8 2005.9 1975.1 2565.2 2382.4 TRUE FALSE FALSE 2114.913772 2152.663387 2493.198061 2505.589459 2465.742792 2130.319982 2062.180155 2577.298898 2283.803978 2465.188223 0.857911681 0.873224757 1.01136215 1.016388702 1.00022496 0.864161188 0.836520366 1.045477532 0.926421746 1 11.26748209 -5.247036001 24.3282023 0.943211302 0.907499779 0.037460871 0.074084539 1855.067755 3133312.976 0.011883659 0.030119008 5.66E-06 5.247036001 -0.035711523 RRS(ph)PPPGPDGHAKK ddPTM_HeLa_Curcumin_4h_R1 2 RRSPPPGPDGHAKK 14 3 P57081-3;P57081-2;P57081 P57081-3 WDR4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 1 0 RRS(1)PPPGPDGHAKK;RRS(1)PPPGPDGHAKK ; 80.318 0.0054898 20730400 11293.5 10779.2 8941.2 8263.4 6960.6 11820.7 8104 8013.5 10440 12210.8 TRUE FALSE FALSE 10399.60756 11710.90602 9272.568737 8229.20824 6877.599391 9368.953573 8331.376429 10456.77926 9294.75812 12635.12439 0.823071245 0.926853243 0.733872374 0.651296179 0.544323837 0.741500699 0.659382225 0.827596068 0.735628541 1 13.62515225 -6.676112185 3.709745552 0.915392599 0.67955568 0.426874998 0.096912269 0.11999631 3.227523251 0.014804687 0.02108715 2.11E-07 6.676112185 -0.235836918 RRS(ph)QS(ph)IEQESQEK ddPTM_HeLa_Curcumin_4h_R1 2 RRSQSIEQESQEK 13 2 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 2 0 RRS(1)QS(1)IEQESQEK;RRS(1)QS(1)IEQESQEK ; 119.08 0.0019096 256050000 12979.9 11712.4 12754.4 12356.2 12380.7 14375.2 12710.4 13331.3 14015 12630 TRUE FALSE FALSE 11952.52722 12724.76767 13227.08928 12305.07332 12233.06824 11393.62148 13067.01962 17395.952 12477.58956 13068.89156 0.914578498 0.973668471 1.012104908 0.941554474 0.936044819 0.871812382 0.999856763 1.331096208 0.954755 1 13.67384916 -4.271651802 4.075622009 0.955351171 1.359908734 0.895914947 0.038624536 0.055335787 1.962551957 0.00617691 0.06453349 5.35E-05 4.271651802 0.404557563 RRS(ph)SDEDAAGEPK ddPTM_HeLa_Curcumin_4h_R1 2 RRSSDEDAAGEPK 13 2 E9PHH9;Q9BUI4 E9PHH9 POLR3C DNA-directed RNA polymerase III subunit RPC3 1 0 RRS(0.847)S(0.153)DEDAAGEPK;RRS(0.911)S(0.089)DEDAAGEPK ; 89.484 0.0093491 71181000 12437.5 12508.2 11733.2 10247 10914.1 16490.3 13082.7 10517.9 11333.8 13387 TRUE FALSE FALSE 11453.05875 13589.35307 12168.04271 10204.60063 10783.95649 13070.0259 13449.76535 13724.75929 10090.5105 13852.19725 0.82680448 0.981025091 0.878419683 0.736677398 0.778501511 0.943534492 0.970948154 0.990800163 0.72844115 1 13.75782722 -5.008068779 23.4960562 0.894898332 0.974966024 0.149306045 0.094831133 301.57784 878209.8359 0.013743223 0.038655593 9.82E-06 5.008068779 0.080067692 RRS(ph)ST(ph)VAPAQPDGAESEWTDVETR ddPTM_HeLa_Curcumin_4h_R1 2 RRSSTVAPAQPDGAESEWTDVETR 24 2 Q02241-2;A0A2U3TZL8;H7BYN4;Q02241-3;Q02241 Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 2 0 RRS(0.567)S(0.567)T(0.865)VAPAQPDGAESEWTDVETR;RRS(0.648)S(0.648)T(0.705)VAPAQPDGAESEWTDVETR ; 130.45 4.51E-06 14502000 1546.84 1533.67 1572.89 1763.91 1979.52 2277.3 1635.52 1008.98 1949.08 1472.26 TRUE FALSE FALSE 1424.405982 1666.233601 1631.182687 1756.611408 1955.915517 1804.96231 1681.408289 1316.613357 1735.2708 1523.420925 0.935004868 1.093744725 1.070736695 1.15307029 1.283896974 1.184808663 1.103705654 0.864247914 1.139061944 1 10.5730989 -7.14142133 4.059469647 0.969422212 1.120513759 0.033907321 0.114673609 0.216655081 6.150297077 0.017631202 0.021759599 7.22E-08 7.14142133 0.151091547 RRT(ph)CETGEPMEAESGDTSSEGPAQVYLPGR ddPTM_HeLa_Curcumin_4h_R1 2 RRTCETGEPMEAESGDTSSEGPAQVYLPGR 30 2 Q9BQ67 Q9BQ67 GRWD1 Glutamate-rich WD repeat-containing protein 1 1 0 RRT(0.471)CET(0.471)GEPMEAES(0.012)GDT(0.014)S(0.016)S(0.016)EGPAQVYLPGR;RRT(0.776)CET(0.215)GEPMEAES(0.002)GDT(0.002)S(0.002)S(0.002)EGPAQVYLPGR ; 50.723 0.0037137 37332000 922.27 729.4 747.61 771.04 779.23 940.76 521.31 458.583 1017.34 876.51 TRUE FALSE FALSE 849.2713563 792.4460859 775.3170843 767.8496408 769.9381912 745.6357714 535.9365556 598.4028456 905.7403473 906.9686573 0.93638446 0.873730398 0.854844407 0.846610999 0.84891378 0.822118565 0.590909676 0.659783379 0.998645697 1 9.824908885 -3.1484204 0.255024747 1.00212972 1.03E-11 0.864593752 0.046001609 3.938765902 0.126639215 0.026764253 1.371462302 0.000710525 3.1484204 -1.00212972 RRVNDAEPGS(ph)PEAPQGK ddPTM_HeLa_Curcumin_4h_R1 2 RRVNDAEPGSPEAPQGK 17 2 Q8N8A6 Q8N8A6 DDX51 ATP-dependent RNA helicase DDX51 1 0 RRVNDAEPGS(1)PEAPQGK;RRVNDAEPGS(1)PEAPQGK ; 141.74 0.00023723 9052000 3873.6 2787.6 3217.5 3422.6 2575 3561.9 2354.8 2418.7 4716.6 3369.1 TRUE FALSE FALSE 3567.000473 3028.547723 3336.74338 3408.438188 2544.294807 2823.121789 2420.86935 3156.150496 4199.20078 3486.175974 1.023184285 0.868730593 0.957135671 0.97770113 0.729823975 0.809804729 0.694419722 0.905333098 1.204529207 1 11.76742968 -6.064716579 1.043529308 1.004418777 0.775562089 0.529430886 0.098137481 0.235196273 0.504518315 0.012235751 0.029188326 8.62E-07 6.064716579 -0.228856689 RRVPRVS(ph)S(ph)EPPAS(ph)IR ddPTM_HeLa_Curcumin_4h_R1 2 RRVPRVSSEPPASIR 15 3 P12755 P12755 SKI Ski oncogene 3 0 RRVPRVS(1)S(1)EPPAS(1)IR;RRVPRVS(1)S(1)EPPAS(1)IR ; 84.41 0.0048051 9383800 3068.2 2673.4 2565.8 2669.3 2636.7 3408.5 2296.7 2130.77 3132.5 2544.5 TRUE FALSE FALSE 2825.348732 2904.476784 2660.890805 2658.255144 2605.259075 2701.538678 2361.139221 2780.431964 2788.872587 2632.921186 1.073085191 1.103138521 1.010623037 1.009621996 0.989493757 1.026061355 0.896775503 1.05602552 1.059231322 1 11.36244862 -6.242300971 2.327511126 1.040655474 0.988903784 0.249557827 0.04685641 0.395011529 4.192882443 0.007759888 0.01337816 5.72E-07 6.242300971 -0.051751691 S(ph)RSSDIVSSVR ddPTM_HeLa_Curcumin_4h_R1 2 SRSSDIVSSVR 11 1 Q14C86-4;Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;F8W9S7;Q14C86-3;H0Y4E7;H0Y7I9;C9IZ08 Q14C86-4 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 0 S(0.333)RS(0.333)S(0.333)DIVSSVR;S(0.465)RS(0.465)S(0.07)DIVSSVR ; 101.45 0.0044606 184067000 4665.1 3405.2 3879.6 4015.6 4000.2 6081 6856.3 9794.4 3962.9 4029.4 TRUE FALSE FALSE 4295.852412 3699.530315 4023.381389 3998.984511 3952.500228 4819.732053 7048.669325 12780.66747 3528.179785 4169.42135 1.030323407 0.88730066 0.964973566 0.959122184 0.947973327 1.155971452 1.690562966 3.065333628 0.846203703 1 12.02563146 -4.205361052 1.562904395 0.992097684 4.055714548 0.989710142 0.065430673 0.068392734 0.138888285 0.007878885 0.332292257 6.23E-05 4.205361052 3.063616863 up RS(ph)ASPDDDLGSSNWEAADLGNEER ddPTM_HeLa_Curcumin_4h_R1 1 RSASPDDDLGSSNWEAADLGNEER 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 0 RS(0.472)AS(0.398)PDDDLGS(0.108)S(0.022)NWEAADLGNEER 47.159 0.016319 8231600 1651.2 1529 1191.9 1418.1 1455.9 1672.9 1349.1 1200.7 1595.2 1306.7 TRUE FALSE FALSE 1520.505778 1661.159947 1236.072863 1412.232278 1438.539343 1325.921683 1386.952115 1566.787903 1420.210551 1352.107728 1.124544847 1.228570707 0.914182234 1.044467278 1.063923616 0.980633167 1.025770422 1.15877446 1.050367897 1 10.40099439 RS(ph)ASPDDDLGSSNWEAADLGNEERK ddPTM_HeLa_Curcumin_4h_R1 1 RSASPDDDLGSSNWEAADLGNEERK 25 2 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 0 RS(0.5)AS(0.5)PDDDLGSSNWEAADLGNEERK 135.21 3.32E-08 20021000 2015.1 1619.6 1757.9 1964.8 1576.3 2093.8 1478.5 1340.2 2299.8 1816 TRUE FALSE FALSE 1855.602709 1759.591007 1823.04932 1956.670178 1557.503652 1659.522278 1519.982731 1748.82081 2047.517694 1879.105865 0.987492373 0.936398018 0.970168501 1.041277245 0.828853595 0.883144643 0.808886162 0.930666464 1.089623385 1 10.87583063 -5.756159097 24.99999806 0.990103345 0.860477372 0.651172149 0.050011479 48.17592258 228090.8616 0.005244304 0.010244699 1.75E-06 5.756159097 -0.129625973 RS(ph)DSAISVR ddPTM_HeLa_Curcumin_4h_R1 2 RSDSAISVR 9 1 H3BR17;Q6Q0C0;Q6Q0C0-2 H3BR17 TRAF7 E3 ubiquitin-protein ligase TRAF7 1 0 RS(0.737)DS(0.263)AISVR;RS(0.579)DS(0.418)AIS(0.002)VR ; 126.66 0.0021142 21137500 2985.3 2587.04 2334.12 2499.31 2060.98 2718.37 2455.14 2604.68 2806.7 2387.67 TRUE FALSE FALSE 2749.010355 2810.65221 2420.624541 2488.968517 2036.40416 2154.54942 2524.024621 3398.834942 2498.812032 2470.641355 1.112670744 1.137620482 0.979755534 1.007417978 0.824241105 0.872060777 1.021607048 1.375689327 1.011402172 1 11.27066988 -6.705117137 24.99978772 1.061024039 0.998529131 0.024189499 0.142935352 254.6215638 113017.8544 0.02299419 0.032518679 1.97E-07 6.705117137 -0.062494908 RS(ph)DSLLSFR ddPTM_HeLa_Curcumin_4h_R1 1 RSDSLLSFR 9 1 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 0 RS(0.976)DS(0.024)LLSFR 102.05 0.0055913 28975000 1539.4 1086.6 1164.1 1458.3 1308.5 1584.5 1295.8 1073.8 1267.3 1053.6 TRUE FALSE FALSE 1417.554866 1180.520862 1207.24257 1452.265941 1292.896992 1255.856839 1332.156661 1401.196677 1128.280361 1090.212522 1.300255535 1.082835538 1.107346087 1.332094351 1.185912807 1.15193764 1.221923831 1.285250948 1.034917815 1 10.09039368 -9.48698274 1.160072372 0.996900509 1.213134938 0.489166029 0.07779336 0.338826889 0.796751815 0.060256565 0.013857978 3.26E-10 9.48698274 0.216234429 RS(ph)DVQEES(ph)EGSDTDDNKDSAAFEDNEVQDEFLEK ddPTM_HeLa_Curcumin_4h_R1 1 RSDVQEESEGSDTDDNKDSAAFEDNEVQDEFLEK 34 2 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 2 0 RS(0.531)DVQEES(0.46)EGS(0.46)DT(0.46)DDNKDS(0.087)AAFEDNEVQDEFLEK 47.96 0.0057619 11005000 2576.7 1912.5 2603.4 2714.9 2934.2 3368.7 2766.4 1570.6 3294.8 1971.1 TRUE FALSE FALSE 2372.751476 2077.807978 2699.884294 2703.666463 2899.211581 2669.993647 2844.017739 2049.46871 2933.368683 2039.595578 1.163344097 1.018735283 1.323735118 1.32558949 1.421463947 1.309079935 1.394402777 1.00484073 1.438210945 1 10.9940674 -6.755278344 24.98690695 1.074909987 1.308539673 0.075806114 0.161695583 94.15928612 381873.981 0.018353328 0.025578572 1.76E-07 6.755278344 0.233629686 RS(ph)ESPPAELPSLR ddPTM_HeLa_Curcumin_4h_R1 2 RSESPPAELPSLR 13 1 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 0 RS(0.5)ES(0.5)PPAELPSLR;RS(0.402)ES(0.402)PPAELPS(0.196)LR ; 140.75 0.00045017 33047400 4863.7 4282.9 4091.1 5542.3 4888.2 5495.3 4573.1 2801.1 5403.1 4512.1 TRUE FALSE FALSE 4478.733013 4653.094792 4242.719765 5519.367431 4829.911408 4355.512835 4701.408878 3655.142495 4810.393448 4668.895139 0.959270423 0.996615827 0.908720294 1.182157077 1.034487018 0.932878702 1.006963904 0.782870976 1.030306594 1 12.18886547 -4.25886402 24.54247589 0.991786585 0.78287088 0.455701426 0.071621663 130.0970716 1239693.147 0.009457858 0.085903472 5.51E-05 4.25886402 -0.208915705 RS(ph)HSPSIDGTPK ddPTM_HeLa_Curcumin_4h_R1 1 RSHSPSIDGTPK 12 1 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 0 RS(0.934)HS(0.066)PS(0.001)IDGTPK 78.326 0.012322 9398700 6858.5 5396.8 5343.6 6256 6113.1 7201.5 6302.8 4365 6870.1 5373.3 TRUE FALSE FALSE 6315.642488 5863.275344 5541.638517 6230.11433 6040.205275 5707.827722 6479.639605 5695.868406 6116.467218 5560.021775 1.135902474 1.054541795 0.996693672 1.120519772 1.086363601 1.026583699 1.165398242 1.024432752 1.100079724 1 12.44087482 -9.601799128 1.407736033 1.000111441 1.084422417 0 0.059390941 0.450282212 1.604647024 0.035523033 0.008252811 2.50E-10 9.601799128 0.084310976 RS(ph)LTVSDDAESSEPER ddPTM_HeLa_Curcumin_4h_R1 2 RSLTVSDDAESSEPER 16 1 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 RS(0.992)LT(0.008)VSDDAESSEPER;RS(0.998)LT(0.002)VSDDAESSEPER ; 128.74 0.00022308 29716000 1903.54 1546.07 1488.85 1910.28 1681.74 1941.28 1311.85 1133.06 2165.45 1792.36 TRUE FALSE FALSE 1752.8728 1679.705402 1544.028091 1902.375768 1661.686349 1538.636645 1348.65698 1478.524778 1927.905553 1854.644377 0.945126097 0.905675192 0.83251976 1.025736142 0.895959554 0.829612763 0.727178211 0.79720123 1.039501468 1 10.85692686 -1.822892435 0.222740773 0.999654983 3.49E-18 0.631284689 0.059895905 16.07442791 0.266721126 0.043323694 5.422181566 0.015035143 1.822892435 -0.999654983 RS(ph)NSSEALLVDR ddPTM_HeLa_Curcumin_4h_R1 1 RSNSSEALLVDR 12 1 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 0 RS(0.926)NS(0.056)S(0.019)EALLVDR 85.976 0.0058314 0 935.98 751.13 1101 932.89 843.32 1585.6 894.3 470.4 1337.7 1093.2 TRUE FALSE FALSE 861.8961954 816.0543302 1141.804029 929.0299484 833.2639598 1256.728687 919.3916511 613.8227945 1190.957657 1131.188619 0.761938532 0.721413137 1.009384297 0.821286506 0.736626895 1.110980668 0.812766002 0.542635228 1.052837376 1 10.14362379 -9.40842562 1.120858056 1.000577256 0.820265835 0.236852422 0.148892997 0.71610188 1.601325266 0.10094705 0.025292663 3.90E-10 9.40842562 -0.180311422 AGS(ph)PDVLR ddPTM_HeLa_Curcumin_4h_R1 2 AGSPDVLR 8 0 Q8NDX6 Q8NDX6 ZNF740 Zinc finger protein 740 1 0 AGS(1)PDVLR;AGS(1)PDVLR ; 91.265 0.020166 159928000 13169.8 6677.5 11367.2 12348.5 12826.1 15425 10633 2296.11 13877 10543.4 TRUE FALSE FALSE 12127.39643 7254.673346 11788.47843 12297.40518 12673.15713 12225.68112 10931.33336 2996.183369 12354.72782 10909.78237 1.111607549 0.664969575 1.080542034 1.127190696 1.161632442 1.120616408 1.001975383 0.274632735 1.132444938 1 13.4133347 -4.262689683 4.953992272 1.045337015 0.236235013 0.742260119 0.136340435 0.063173994 4.714751197 0.018423268 0.174588932 5.46E-05 4.262689683 -0.809102001 down RS(ph)PS(ph)PAPPPR ddPTM_HeLa_Curcumin_4h_R1 2 RSPSPAPPPR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 0 RS(1)PS(1)PAPPPR;RS(1)PS(1)PAPPPR ; 80.905 0.012561 32666000 2886.5 2804 2643.5 2935.1 2435.5 3579.4 2279.37 2140.1 3464.9 2895.7 TRUE FALSE FALSE 2658.030479 3046.365266 2741.470435 2922.955334 2406.458253 2836.992092 2343.322988 2792.606638 3084.809139 2996.325359 0.887096747 1.016700425 0.914944175 0.975513332 0.803136497 0.946823776 0.782065599 0.932010481 1.029530765 1 11.54897857 -5.778012579 24.99876524 0.950434583 0.865785588 0.368118381 0.06394621 220.4592329 332537.1627 0.008997237 0.016341772 1.67E-06 5.778012579 -0.084648995 RS(ph)PS(ph)PYYSR ddPTM_HeLa_Curcumin_4h_R1 1 RSPSPYYSR 9 1 P62995;H7C2L4;P62995-3;H7BXF3;Q13595;Q13595-4;Q13595-3 P62995;Q13595 TRA2B;TRA2A Transformer-2 protein homolog beta;Transformer-2 protein homolog alpha 2 0 RS(0.999)PS(0.948)PY(0.05)Y(0.002)S(0.001)R 113.67 0.012222 445220000 3793.4 4262.5 3954.4 4528.6 3242.7 4337.8 3137 3419.7 5310.6 3975.2 TRUE FALSE FALSE 3493.148387 4630.931507 4100.953543 4509.861853 3204.03292 3438.091383 3225.015777 4462.350788 4728.040466 4113.337904 0.849224758 1.125832989 0.996989219 1.096399556 0.778937446 0.835839764 0.784038621 1.084849067 1.1494413 1 12.00609388 -5.740068557 24.99992089 0.959719476 0.862205268 0.157901681 0.126806615 389.2769077 455379.6656 0.01722944 0.034432212 1.82E-06 5.740068557 -0.097514208 RS(ph)PSPYYSR ddPTM_HeLa_Curcumin_4h_R1 1 RSPSPYYSR 9 1 P62995;H7C2L4;P62995-3;H7BXF3;Q13595;Q13595-4;Q13595-3 P62995;Q13595 TRA2B;TRA2A Transformer-2 protein homolog beta;Transformer-2 protein homolog alpha 1 0 RS(0.996)PS(0.004)PYYSR 72.289 0.01992 5931500 214.43 147.6 186.94 162.64 276.79 275.5 136.28 128.41 411.03 149.38 TRUE FALSE FALSE 197.4576392 160.3578863 193.8681608 161.9670388 273.48946 218.3581945 140.10365 167.5616179 365.9410373 154.5709439 1.277456385 1.037438747 1.254234179 1.047849193 1.769345863 1.412672971 0.906403536 1.084043441 2.367463303 1 7.272125338 RS(ph)PTDSDVSLDSEDSGAK ddPTM_HeLa_Curcumin_4h_R1 3 RSPTDSDVSLDSEDSGAK 18 1 Q8N3V7-2 Q8N3V7-2 SYNPO Synaptopodin 1 0 RS(0.916)PT(0.083)DS(0.001)DVSLDSEDSGAK;RS(0.5)PT(0.5)DS(0.001)DVSLDSEDSGAK;RS(0.75)PT(0.249)DS(0.001)DVSLDSEDSGAK ;; 166.93 7.06E-06 67308000 13006.6 10145.4 10275.3 11204.9 11236.9 14488.8 10741.5 6778.6 12688.6 10558 TRUE FALSE FALSE 11977.11389 11022.32317 10656.11166 11158.53709 11102.90731 11483.65956 11042.87758 8845.363935 11296.69233 10924.88971 1.096314398 1.008918484 0.975397641 1.021386704 1.016294681 1.051146497 1.010799914 0.809652469 1.034032619 1 13.4153311 -4.262931379 3.753723221 1.035233852 0.786460778 0.801690827 0.031724065 0.106325056 2.835551228 0.005911152 0.072927551 5.46E-05 4.262931379 -0.248773074 RS(ph)PTS(ph)SPTPQR ddPTM_HeLa_Curcumin_4h_R1 2 RSPTSSPTPQR 11 1 A0A0D9SFB1;A0A0U1RQP1;A0A0D9SFE4;Q05193-5;Q05193-3;Q05193-2;Q05193 A0A0D9SFB1 DNM1 Dynamin-1 2 0 RS(0.999)PT(0.053)S(0.902)S(0.042)PT(0.004)PQR;RS(0.999)PT(0.306)S(0.682)S(0.011)PT(0.002)PQR ; 109.55 0.0028158 46947000 7288.9 6442 6662 7179.5 7454.5 8106.9 5820.6 5245.5 7719 6568.9 TRUE FALSE FALSE 6711.975874 6998.817775 6908.89958 7149.793131 7365.609956 6425.437556 5983.910371 6844.828803 6872.245012 6797.168786 0.987466412 1.029666615 1.016437843 1.051878121 1.083629109 0.945310873 0.880353359 1.007011745 1.01104522 1 12.73071823 -5.033363498 24.83508105 1.008262098 0.935969925 0.411105435 0.040934278 435.0990912 323878.5695 0.005885011 0.015015189 9.26E-06 5.033363498 -0.072292173 RS(ph)PTVEPSTLPR ddPTM_HeLa_Curcumin_4h_R1 4 RSPTVEPSTLPR 12 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 RS(0.997)PT(0.003)VEPSTLPR;RS(0.995)PT(0.005)VEPSTLPR;RS(0.958)PT(0.041)VEPSTLPR;RS(0.988)PT(0.012)VEPSTLPR ;;; 125.36 0.0014144 93561000 8718.9 7439.5 7349.1 7779.8 7406.3 5501.74 4485.33 5999.9 8278.3 7785.5 TRUE FALSE FALSE 8028.789865 8082.53723 7621.464111 7747.609249 7317.98471 4360.617107 4611.176288 7829.24189 7370.191201 8056.045545 0.996616742 1.003288423 0.946055241 0.961713685 0.908384228 0.541285061 0.572387068 0.971846776 0.914864639 1 12.97585612 -5.445141395 4.971831815 0.990424119 0.684151503 0.543738734 0.111815154 0.102839769 4.547969373 0.014684337 0.03323829 3.59E-06 5.445141395 -0.306272616 GAGATSGS(ph)PPAGRN ddPTM_HeLa_Curcumin_4h_R1 2 GAGATSGSPPAGRN 14 1 B4DEE8;P16455 B4DEE8 MGMT Methylated-DNA--protein-cysteine methyltransferase 1 0 GAGAT(0.006)S(0.208)GS(0.785)PPAGRN;GAGAT(0.003)S(0.036)GS(0.961)PPAGRN ; 133.98 0.0015152 140925000 6759.9 5120.26 5645.07 5597.83 5207.32 7803.73 5584.3 2175.89 6855.49 5619.67 TRUE FALSE FALSE 6224.846782 5562.832459 5854.28126 5574.667663 5145.22611 6185.148432 5740.980429 2839.308844 6103.459899 5814.953114 1.070489591 0.956642702 1.006763278 0.958678007 0.884826758 1.063662649 0.987278885 0.488277169 1.049614636 1 12.50555184 -4.26241518 5.197614515 1.012709704 0.465643782 0.885749339 0.054702563 0.038488142 3.505699475 0.00815912 0.075002104 5.46E-05 4.26241518 -0.547065922 down LFSLS(ph)NPSLSTTNLSGPSR ddPTM_HeLa_Curcumin_4h_R1 2 LFSLSNPSLSTTNLSGPSR 19 0 Q6UUV7;Q6UUV7-3 Q6UUV7 CRTC3 CREB-regulated transcription coactivator 3 1 0 LFS(0.116)LS(0.556)NPS(0.313)LS(0.015)T(0.001)TNLSGPSR;LFSLS(0.867)NPS(0.125)LS(0.004)T(0.004)TNLSGPSR ; 156 3.11E-05 73205000 2593.07 2092.13 2252.78 2101.14 2433.09 3029.54 2125.72 562.23 2497.94 2000.78 TRUE FALSE FALSE 2387.825773 2272.964395 2336.270009 2092.446039 2404.076991 2401.179254 2185.361982 733.6513388 2223.922232 2070.306956 1.15336799 1.097887629 1.128465517 1.010693624 1.161217656 1.159817991 1.055573897 0.354368388 1.074199275 1 11.01562897 -4.262308335 5.414390438 1.087000718 0.326591526 0.941420548 0.055343495 0.030541977 3.314752486 0.009565583 0.085814916 5.47E-05 4.262308335 -0.760409192 down RS(ph)S(ph)LSPPSSAYER ddPTM_HeLa_Curcumin_4h_R1 1 RSSLSPPSSAYER 13 1 Q9BYW2 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 2 0 RS(0.991)S(0.874)LS(0.135)PPSSAYER 64.224 0.018256 10175000 2427.2 1971.9 1854.6 1936.9 2282.7 2392.5 2216.5 1580.4 2542.9 2409.8 TRUE FALSE FALSE 2235.084559 2142.342249 1923.333107 1928.885621 2255.480293 1896.268531 2278.689025 2062.256685 2263.950232 2493.540371 0.896349859 0.859156834 0.771326236 0.773552995 0.904529287 0.76047236 0.913836829 0.827039622 0.907926039 1 11.28397985 -8.066324323 0.74450811 0.986804967 0.827874684 0.407185529 0.056792636 0.277092452 0.337350463 0.018532224 0.012621684 8.58E-09 8.066324323 -0.158930283 RS(ph)S(ph)NVS(ph)Y(ph)KYS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 RSSNVSYKYSK 11 2 P11717 P11717 IGF2R Cation-independent mannose-6-phosphate receptor 5 0 RS(0.991)S(1)NVS(1)Y(1)KY(0.46)S(0.55)K 40.715 0.017893 1069400 566.96 472.71 558.75 571.97 445.34 633.51 598.16 412.66 512.68 673.87 TRUE FALSE FALSE 522.0845177 513.568946 579.4577665 569.6033397 440.0296114 502.1128849 614.9427597 538.4781343 456.4402867 697.2869323 0.748736988 0.736524553 0.831017677 0.816885149 0.631059598 0.720095074 0.881907765 0.772247563 0.654594637 1 9.445608635 -9.229418429 0.758661749 1.015574066 0.765700592 0 0.125002909 0.401967211 0.376445712 0.062418846 0.013729194 5.90E-10 9.229418429 -0.249873475 RS(ph)S(ph)RIMEET(ph)SGMEEEEEEESIAAVPGR ddPTM_HeLa_Curcumin_4h_R1 1 RSSRIMEETSGMEEEEEEESIAAVPGR 27 2 J3KPG5;F8VU39;Q9UIF9-2;Q9UIF9-3;Q9UIF9 J3KPG5 BAZ2A Bromodomain adjacent to zinc finger domain protein 2A 3 0 RS(0.979)S(0.906)RIMEET(0.558)S(0.558)GMEEEEEEESIAAVPGR 46.273 0.0085713 0 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 RS(ph)S(ph)SASPQEQDQDR ddPTM_HeLa_Curcumin_4h_R1 1 RSSSASPQEQDQDR 14 1 O00411 O00411 POLRMT "DNA-directed RNA polymerase, mitochondrial" 2 0 RS(0.657)S(0.657)S(0.657)AS(0.03)PQEQDQDR 63.76 0.017665 11646000 2440 3936.3 3686.7 2776.9 2611 2850 3310.8 2232.5 2139.2 3520 TRUE FALSE FALSE 2246.871425 4276.536232 3823.332345 2765.409924 2579.86553 2258.877874 3403.692137 2913.178973 1904.535112 3642.319738 0.616879238 1.174124333 1.049697067 0.759244142 0.708302872 0.620175612 0.934484719 0.79981418 0.522890699 1 11.83064186 ISHEGS(ph)PVKPVAIR ddPTM_HeLa_Curcumin_4h_R1 1 ISHEGSPVKPVAIR 14 1 Q96II8-3;Q96II8;Q96II8-2 Q96II8-3 LRCH3 Leucine-rich repeat and calponin homology domain-containing protein 3 1 0 IS(0.004)HEGS(0.996)PVKPVAIR 87.669 0.0052906 79390000 2744.2 2381 2186 2551.2 2638.5 2995.5 2080.5 712.75 2751.6 1863.2 TRUE FALSE FALSE 2526.993674 2586.80303 2267.015083 2540.64381 2607.037611 2374.199534 2138.873231 930.0641939 2449.756364 1927.946061 1.310718036 1.341740354 1.175870595 1.31779818 1.352235762 1.231465746 1.10940512 0.482411937 1.270656069 1 10.91284897 -4.262133488 3.503058662 1.196752663 0.396346443 0.809136856 0.108999643 0.131629661 2.79024871 0.020581525 0.2774637 5.47E-05 4.262133488 -0.800406221 down RS(ph)SDPALIGLSTSVSDSNFSSEEPSR ddPTM_HeLa_Curcumin_4h_R1 3 RSSDPALIGLSTSVSDSNFSSEEPSR 26 1 Q5VWV2;Q8TEW0-4;Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-3;Q8TEW0-7;Q8TEW0-6;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 Q5VWV2 PARD3 Partitioning defective 3 homolog 1 0 RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR;RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR;RS(0.5)S(0.5)DPALIGLSTSVSDSNFSSEEPSR ;; 146.75 2.08E-08 120321000 7477.5 5720.9 5217.64 5974.8 6530.5 8141.4 5665.99 4253.24 7882.7 6033.2 TRUE FALSE FALSE 6885.647985 6215.389104 5411.010328 5950.077861 6452.628053 6452.781868 5824.96243 5550.033296 7017.987532 6242.853251 1.102964896 0.995600706 0.866752767 0.953102311 1.033602392 1.03362703 0.933060925 0.889021906 1.124163463 1 12.60798984 -7.005073383 24.97142695 1.048657077 0.955968672 0.441817399 0.060041825 201.7551051 993052.9253 0.010446678 0.013521805 9.88E-08 7.005073383 -0.092688406 RS(ph)SELLVR ddPTM_HeLa_Curcumin_4h_R1 1 RSSELLVR 8 1 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 0 RS(0.936)S(0.064)ELLVR 73.841 0.0095266 0 1223.7 1134.5 1279.1 1210.5 1138.2 1536.7 1244.5 1077.6 1124.8 1000.9 TRUE FALSE FALSE 1126.842854 1232.561125 1326.504571 1205.491272 1124.627708 1217.971098 1279.417321 1406.155279 1001.412254 1035.6812 1.08802096 1.190097034 1.280803949 1.163959789 1.08588213 1.176009661 1.235338944 1.357710537 0.966911684 1 10.01636427 -1.000000008 0.062004646 0.699657559 2.151345101 0.674169131 0.066024667 139.3173939 0.650549388 3.055708339 18.22476176 0.099999998 1.000000008 1.451687542 RS(ph)SFSMEEGDVL ddPTM_HeLa_Curcumin_4h_R1 1 RSSFSMEEGDVL 12 1 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 0 RS(0.453)S(0.453)FS(0.093)MEEGDVL 109.84 0.0088615 31501000 4398.3 3419.3 4205.1 3673.7 3618.7 4755 3596.8 3136.9 4563.8 3763.1 TRUE FALSE FALSE 4050.169914 3714.849056 4360.944705 3658.499203 3575.549366 3768.7594 3697.716528 4093.326369 4063.162558 3893.867445 1.040140675 0.954025556 1.119952019 0.939554121 0.918251434 0.967870492 0.949625682 1.051223861 1.043477369 1 11.92698806 RS(ph)SGFISELPSEEGK ddPTM_HeLa_Curcumin_4h_R1 1 RSSGFISELPSEEGK 15 1 Q5VZK9;Q5VZK9-2;A0A0U1RQQ1 Q5VZK9 LRRC16A Leucine-rich repeat-containing protein 16A 1 0 RS(0.742)S(0.231)GFIS(0.027)ELPSEEGK 94.973 0.0026644 82702000 8210.1 6655.8 7352.2 7585.5 7862.1 9409.4 6776.1 3143 8278.1 7177.4 TRUE FALSE FALSE 7560.261922 7231.097694 7624.679 7554.113211 7768.349592 7457.784374 6966.219129 4101.286231 7370.013141 7426.814116 1.017968378 0.973647325 1.02664196 1.017140471 1.045986808 1.00417006 0.937982158 0.552226859 0.992351906 1 12.85852775 -4.241480887 2.717838123 1.010356757 0.450386669 0.981420477 0.018783946 0.043143129 0.404861744 0.002588864 0.055217946 5.73E-05 4.241480887 -0.559970088 RS(ph)SIGLR ddPTM_HeLa_Curcumin_4h_R1 2 RSSIGLR 7 1 Q96GN5-5;Q96GN5-2;Q96GN5;C9IZR6;Q96GN5-4;C9J8L0 Q96GN5-5 CDCA7L Cell division cycle-associated 7-like protein 1 0 RS(0.997)S(0.003)IGLR;RS(0.988)S(0.012)IGLR ; 92.051 0.011491 18318000 2117.78 1857.91 2014.45 1756.37 2031.98 2554.9 2919.2 2377.64 1980.56 2208.13 TRUE FALSE FALSE 1950.155478 2018.499462 2089.107289 1749.102606 2007.749966 2024.98494 3001.104895 3102.571491 1763.297523 2284.862353 0.853511143 0.883422784 0.914325227 0.765517714 0.878718126 0.886261239 1.31347295 1.357881137 0.771730306 1 11.15789154 -4.747484662 7.46874766 0.906816782 1.339079075 0.865314238 0.072419486 0.039997913 11.29445987 0.010567362 0.037381897 1.79E-05 4.747484662 0.432262293 RPEAS(ph)PVQK ddPTM_HeLa_Curcumin_4h_R1 1 RPEASPVQK 9 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 RPEAS(1)PVQK 84.169 0.01267 4391700 2195.8 2308.4 1829 2384.6 2678.6 3056.3 2154.5 715.48 3094.7 2548.1 TRUE FALSE FALSE 2022.000113 2507.92781 1896.784349 2374.733157 2646.659444 2422.388928 2214.949471 933.6265583 2755.219153 2636.646285 0.766883341 0.951180985 0.719392798 0.900664291 1.003797688 0.91873868 0.840063183 0.354096249 1.044971094 1 11.36448833 -4.26202929 3.962935801 0.890204978 0.305088619 0.736389947 0.098984507 0.100538494 3.22807445 0.014417828 0.168723884 5.47E-05 4.26202929 -0.585116359 down RS(ph)SLDAEIDSLTSILADLECSSPYKPRPPQSSTGSTASPPVSTPVTGHK ddPTM_HeLa_Curcumin_4h_R1 1 RSSLDAEIDSLTSILADLECSSPYKPRPPQSSTGSTASPPVSTPVTGHK 49 3 C9JUT4;A0A087WZF1;Q93052 C9JUT4 LPP Lipoma-preferred partner 1 0 RS(0.48)S(0.48)LDAEIDS(0.014)LT(0.014)S(0.005)ILADLECS(0.001)S(0.001)PY(0.001)KPRPPQS(0.001)S(0.001)T(0.001)GS(0.001)T(0.001)AS(0.001)PPVSTPVTGHK 58.406 4.80E-06 146840000 1684.3 1399.8 1390 1453.3 1825 3069.1 2062.7 1176.8 2069.4 1786.6 TRUE FALSE FALSE 1550.985878 1520.792475 1441.514623 1447.28663 1803.238067 2432.534064 2120.573811 1535.600903 1842.391997 1848.684217 0.838967447 0.822635072 0.779751679 0.782873904 0.975417029 1.315819133 1.14707195 0.830645325 0.996596379 1 10.8522831 -5.514235937 24.21666083 0.892357465 1.109909794 0.364015974 0.132890711 232.6744572 651938.8207 0.019974579 0.04165964 3.06E-06 5.514235937 0.217552329 RS(ph)SPAAFINPPIGTVTPALK ddPTM_HeLa_Curcumin_4h_R1 2 RSSPAAFINPPIGTVTPALK 20 1 Q6R954;F8WEE2;Q8WUT1;F8WCX5;F6VRR5;Q9BY77-2;Q9BY77 Q6R954 PDIP46;POLDIP3 Polymerase delta-interacting protein 3 1 0 RS(0.5)S(0.5)PAAFINPPIGTVTPALK;RS(0.5)S(0.5)PAAFINPPIGTVTPALK ; 148.49 2.31E-05 129746000 8045.7 5741 6467.9 7008 7054.7 9488 8121.9 2925.5 7663.8 6862.8 TRUE FALSE FALSE 7408.874355 6237.226459 6707.606064 6979.002753 6970.57731 7520.081848 8349.778655 3817.471483 6823.100314 7101.281789 1.043315077 0.878324033 0.944562723 0.982780709 0.981594241 1.058975277 1.175812889 0.537574989 0.960826583 1 12.79386374 -4.248840934 24.92921867 1.011534299 0.537574681 0.773391599 0.075435932 671.3278491 1328368.771 0.010236246 0.243649989 5.64E-05 4.248840934 -0.473959618 RS(ph)SPDDGNDVSPYSLSPVSNK ddPTM_HeLa_Curcumin_4h_R1 1 RSSPDDGNDVSPYSLSPVSNK 21 1 K7EQT1;Q9UM11-2;Q9UM11 K7EQT1 FZR1 Fizzy-related protein homolog 1 0 RS(0.572)S(0.416)PDDGNDVS(0.005)PY(0.004)S(0.002)LSPVSNK 62.404 0.0058765 0 2125.7 1799.5 1472.8 1704.1 1628.7 1765.9 1259.1 1362.1 1851.5 1610.2 TRUE FALSE FALSE 1957.448602 1955.040762 1527.383264 1697.048886 1609.278816 1399.632434 1294.426957 1777.39802 1648.395082 1666.15433 1.174830306 1.173385158 0.916711757 1.018542433 0.965864198 0.84003769 0.776894993 1.066766738 0.989341175 1 10.70230632 -6.133148094 1.269999448 1.087507327 0.893674787 0.309208367 0.101251217 0.346752713 1.102790387 0.017825719 0.037232813 7.36E-07 6.133148094 -0.19383254 RS(ph)SPETGTTGDVAWQISPK ddPTM_HeLa_Curcumin_4h_R1 2 RSSPETGTTGDVAWQISPK 19 1 E9PDC2;A0A088AWP5;Q8WUY3-4;Q8WUY3;Q8WUY3-2;Q8WUY3-3;H7BZH9 E9PDC2 PRUNE2 Protein prune homolog 2 1 0 RS(0.295)S(0.214)PET(0.156)GT(0.295)T(0.041)GDVAWQISPK;RS(0.509)S(0.338)PET(0.051)GT(0.051)T(0.051)GDVAWQISPK ; 123.43 8.75E-05 30160000 13278.8 11652.3 12878.8 12976.8 11536.6 13383.3 9952.5 8747.6 14451 12162.5 TRUE FALSE FALSE 12227.76897 12659.47289 13356.09966 12923.10544 11399.03358 10607.45272 10231.74036 11414.70297 12865.76145 12585.14597 0.971603269 1.005905924 1.061259018 1.026853838 0.905752989 0.842854961 0.813001326 0.906998059 1.022297356 1 13.61943433 -5.575706884 3.974449724 0.99645312 0.85240757 0.820936939 0.033677748 0.074585817 2.449407847 0.005217806 0.011058439 2.66E-06 5.575706884 -0.14404555 RS(ph)SPPGHYYQK ddPTM_HeLa_Curcumin_4h_R1 1 RSSPPGHYYQK 11 1 D6RI08;D6RDK1;D6RIV2;D6R9T5;D6RG39;D6RIT9;D6RDK6;D6RBN5;Q9NX40-3;Q9NX40-2;Q9NX40-4;Q9NX40 D6RI08 OCIAD1 OCIA domain-containing protein 1 1 0 RS(0.933)S(0.067)PPGHYYQK 70.977 0.018218 4509900 4317.7 3171.1 3645.6 3672.6 3677 3460.9 1587.2 1438.6 5320 3407.6 TRUE FALSE FALSE 3975.949489 3445.195754 3780.709143 3657.403754 3633.154177 2743.070328 1631.73256 1877.222518 4736.40931 3526.013846 1.127604616 0.977079474 1.072233209 1.037263015 1.03038568 0.777952228 0.462769754 0.532392271 1.343275868 1 11.78382242 -5.019079013 2.313175859 1.054034997 0.488750586 0.840763618 0.102354436 0.048030136 0.500260441 0.008110017 0.02971536 9.57E-06 5.019079013 -0.56528441 RS(ph)SPPPPPSGSSSR ddPTM_HeLa_Curcumin_4h_R1 1 RSSPPPPPSGSSSR 14 1 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 0 RS(0.982)S(0.018)PPPPPSGSSSR 116.98 0.00095661 21873000 789.49 774.28 885.22 904.68 602.11 1154.3 524.24 384.42 896.65 878.19 TRUE FALSE FALSE 727.0010334 841.2053131 918.0270319 900.9366739 594.9302315 914.8851684 538.9487635 501.6278883 798.2897383 908.7070371 0.800038961 0.925716737 1.010256325 0.99144899 0.654699708 1.006798815 0.593094079 0.552023774 0.878489662 1 9.827671441 -4.746545865 22.17455946 0.906242557 0.572557471 0.613834149 0.106548998 32.85466611 48912.49161 0.01571362 0.058088637 1.79E-05 4.746545865 -0.333685086 RS(ph)SPSARPPDVPGQQPQAAK ddPTM_HeLa_Curcumin_4h_R1 1 RSSPSARPPDVPGQQPQAAK 20 2 A0A0A6YYC7;Q96JP5-2;Q96JP5 A0A0A6YYC7 ZFP91-CNTF;ZFP91 E3 ubiquitin-protein ligase ZFP91 1 0 RS(0.473)S(0.473)PS(0.053)ARPPDVPGQQPQAAK 48.5 0.01253 18233000 5165.3 4228.7 5089.7 4996.4 4939.1 5276.4 4443.2 3137.7 5933.2 4783.6 TRUE FALSE FALSE 4756.461055 4594.209985 5278.328759 4975.726221 4880.204458 4182.015163 4567.864234 4094.370286 5282.342804 4949.829744 0.960934275 0.928155153 1.06636572 1.005231791 0.985933802 0.844880608 0.922832596 0.827173963 1.067176666 1 12.27316319 -5.269507493 24.37750473 0.985646715 0.870749409 0.620068473 0.04790514 197.9207665 598011.3753 0.005744578 0.013067538 5.38E-06 5.269507493 -0.114897306 RS(ph)SQPS(ph)PTAVPASDS(ph)PPTKQEVK ddPTM_HeLa_Curcumin_4h_R1 1 RSSQPSPTAVPASDSPPTKQEVK 23 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 3 0 RS(0.884)S(0.306)QPS(0.709)PT(0.102)AVPAS(0.252)DS(0.497)PPT(0.25)KQEVK 43.798 0.018996 19993000 3170.2 2637.5 2796.3 3115.9 2789.4 3538.9 2940.7 2354.3 3510.8 2824 TRUE FALSE FALSE 2919.275325 2865.473748 2899.933338 3103.007231 2756.138227 2804.892248 3023.208128 3072.115232 3125.674024 2922.13379 0.999021788 0.980610045 0.992402657 1.061897728 0.943193716 0.959878106 1.034589223 1.051326001 1.069654659 1 11.51280652 -4.576331968 9.063983463 0.995979272 1.04719382 0.163826225 0.037623073 0.237100702 37.51138909 0.003924884 0.014788286 2.65E-05 4.576331968 0.051214547 RS(ph)SQPSPT(ph)AVPASDS(ph)PPTKQEVK ddPTM_HeLa_Curcumin_4h_R1 1 RSSQPSPTAVPASDSPPTKQEVK 23 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 3 0 RS(0.717)S(0.282)QPS(0.146)PT(0.849)AVPAS(0.172)DS(0.82)PPT(0.014)KQEVK 78.607 0.0013546 21055000 3745.2 2773.9 3013.9 3650.7 3184.1 4188 3389.3 3576.7 4305.4 3340.7 TRUE FALSE FALSE 3448.763468 3013.663556 3125.597785 3635.594371 3146.131687 3319.361592 3484.394636 4667.219365 3833.108392 3456.789076 0.997678305 0.871810078 0.904191062 1.051725833 0.910131228 0.96024418 1.007985897 1.350160297 1.108863835 1 11.75521686 -4.261721504 4.225349273 0.978485043 1.379265006 0.734378568 0.067163777 0.069717645 2.814123172 0.007652342 0.084048603 5.47E-05 4.261721504 0.400779963 RS(ph)SSMSYVDGFIGTWPK ddPTM_HeLa_Curcumin_4h_R1 1 RSSSMSYVDGFIGTWPK 17 1 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 0 RS(0.54)S(0.357)S(0.065)MS(0.038)YVDGFIGTWPK 80.585 0.0045847 0 1862.2 1222.5 1422.8 1607.2 1172.2 1680.1 1628.5 1686 1600.6 1731.1 TRUE FALSE FALSE 1714.804905 1328.167453 1475.53022 1600.549832 1158.222281 1331.628321 1674.191327 2200.053639 1425.018185 1791.255596 0.957320055 0.741472884 0.823740745 0.893535147 0.646597997 0.743404975 0.934646809 1.228218711 0.795541512 1 10.8067555 -7.449973111 8.621717177 0.981277626 0.84892124 0 0.158841796 0.541151749 59.99754295 0.025576708 0.029122266 3.55E-08 7.449973111 -0.132356386 LLES(ph)PGVEAGEGEAEKEEAGAQGRPLR ddPTM_HeLa_Curcumin_4h_R1 1 LLESPGVEAGEGEAEKEEAGAQGRPLR 27 2 A0A0G2JHC2;Q6NYC8;Q6NYC8-3 A0A0G2JHC2 PPP1R18 Phostensin 1 0 LLES(1)PGVEAGEGEAEKEEAGAQGRPLR 55.153 0.0016565 77007000 3025 2424.9 2418.1 2404.3 2378 3916.4 3659.7 7917.3 2616.9 2503.6 TRUE FALSE FALSE 2785.568058 2634.497551 2507.716913 2394.351644 2349.643903 3104.094493 3762.381332 10331.24832 2329.832617 2590.599914 1.075259844 1.01694497 0.968006252 0.924246014 0.906988335 1.198214544 1.452320489 3.987975244 0.899340961 1 11.33907051 -4.205258808 2.4352837 1.021041661 4.939433841 0.990104258 0.089127303 0.043693177 0.275911371 0.012277601 0.377057538 6.23E-05 4.205258808 3.91839218 up RS(ph)STVAPAQPDGAESEWTDVETR ddPTM_HeLa_Curcumin_4h_R1 2 RSSTVAPAQPDGAESEWTDVETR 23 1 Q02241-2;A0A2U3TZL8;H7BYN4;Q02241-3;Q02241 Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 0 RS(0.755)S(0.122)T(0.122)VAPAQPDGAESEWTDVETR;RS(0.8)S(0.1)T(0.1)VAPAQPDGAESEWTDVETR ; 179.86 1.30E-10 57622000 1851.89 1546.59 1808.09 1569.78 2154.89 2141.89 2064.93 2465.8 2586.8 2010.67 TRUE FALSE FALSE 1705.310952 1680.270348 1875.099406 1563.284666 2129.194344 1697.63787 2122.866378 3217.611069 2303.034512 2080.540633 0.819647992 0.807612368 0.901255845 0.751383867 1.023385129 0.815959969 1.020343628 1.546526426 1.106940415 1 11.02274275 -4.277981353 3.043904117 0.895344069 1.637799495 0.764440416 0.10653031 0.107805553 1.505302277 0.013005049 0.188633487 5.27E-05 4.277981353 0.742455426 RS(ph)TQGVTLTDLQEAEK ddPTM_HeLa_Curcumin_4h_R1 3 RSTQGVTLTDLQEAEK 16 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 RS(0.5)T(0.5)QGVT(0.001)LTDLQEAEK;RS(0.499)T(0.499)QGVT(0.003)LTDLQEAEK;RS(0.5)T(0.5)QGVTLTDLQEAEK ;; 150.36 0.00016325 72045400 14112.8 4427.72 16100.6 15392.7 16813.9 26610.2 24119.8 17056.3 15243.1 21384 TRUE FALSE FALSE 12995.75699 4810.432387 16697.3024 15329.00909 16613.40522 21090.94456 24796.53667 22256.68735 13570.97007 22127.09241 0.587323303 0.217400113 0.754608969 0.692771052 0.750817365 0.953172887 1.120641439 1.005856845 0.613319175 1 14.43352627 -5.134973473 3.022528741 0.73946182 1.061295754 0.386508395 0.197356526 0.296033858 5.126259603 0.034940499 0.102955229 7.33E-06 5.134973473 0.321833934 RS(ph)YDVPPPPMEPDHPFYSNISK ddPTM_HeLa_Curcumin_4h_R1 2 RSYDVPPPPMEPDHPFYSNISK 22 1 P18669;Q8N0Y7 P18669 PGAM1;PGAM4 Phosphoglycerate mutase 1;Probable phosphoglycerate mutase 4 1 0 RS(0.549)Y(0.451)DVPPPPMEPDHPFYSNISK;RS(0.536)Y(0.464)DVPPPPMEPDHPFYSNISK ; 94.632 7.61E-05 65531000 4384.2 3601.6 3729.9 3821.5 3746.9 5570.6 3606.5 3883.7 4477.1 3758.7 TRUE FALSE FALSE 4037.185944 3912.906256 3868.133375 3805.687646 3702.220665 4415.194766 3707.688684 5067.822252 3985.973331 3889.314545 1.038019912 1.006065776 0.994554009 0.978498294 0.95189541 1.135211543 0.953301318 1.303011673 1.024852396 1 11.9253002 -4.254107192 24.98933683 1.013486041 1.30301181 0.757811953 0.049782842 305.4144905 1040878.855 0.006280699 0.087296111 5.57E-05 4.254107192 0.289525769 RSAS(ph)PDDDLGSSNWEAADLGNEER ddPTM_HeLa_Curcumin_4h_R1 2 RSASPDDDLGSSNWEAADLGNEER 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 0 RS(0.309)AS(0.672)PDDDLGS(0.01)S(0.01)NWEAADLGNEER;RS(0.199)AS(0.801)PDDDLGSSNWEAADLGNEER ; 115.66 3.35E-07 433905300 1669.93 1296.59 1315.49 1399.18 1580.94 1820.12 1068.93 1268.14 2015.66 1426.68 TRUE FALSE FALSE 1537.753278 1408.661462 1364.243217 1393.390564 1562.088323 1442.606595 1098.921299 1654.790048 1794.547141 1476.257024 1.041656875 0.954211522 0.9241231 0.943867187 1.058141162 0.977205576 0.744396999 1.120936274 1.215606166 1 10.52772821 -7.248071692 22.50498713 1.019671301 0.954476121 0.137335095 0.111085559 354.8875982 597465.1346 0.014347478 0.017499413 5.65E-08 7.248071692 -0.06519518 RSASPDDDLGS(ph)SNWEAADLGNEERK ddPTM_HeLa_Curcumin_4h_R1 1 RSASPDDDLGSSNWEAADLGNEERK 25 2 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 0 RSAS(0.001)PDDDLGS(0.987)S(0.012)NWEAADLGNEERK 121.48 2.40E-08 31328000 1541.8 1025.7 1037.8 1073.8 1298.3 1503.6 1047.1 1052.3 1303.7 1163.7 TRUE FALSE FALSE 1419.764903 1114.356938 1076.261781 1069.3569 1282.81862 1191.736411 1076.478808 1373.141426 1160.687372 1204.138488 1.179071109 0.925439182 0.893802325 0.888068034 1.065341431 0.989700456 0.89398256 1.140351744 0.963915183 1 10.23378561 -7.244390216 24.95898764 1.08456136 0.96619046 0.083050309 0.094642389 855.7010285 1252697.666 0.016286603 0.019921095 5.70E-08 7.244390216 -0.1183709 RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV ddPTM_HeLa_Curcumin_4h_R1 1 RSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV 31 1 H3BRW9;Q02750-2;Q02750 H3BRW9 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 1 0 RSDAEEVDFAGWLCS(0.082)T(0.082)IGLNQPS(0.377)T(0.377)PT(0.082)HAAGV 69.952 4.87E-05 18892000 77.721 0 0 0 0 143.07 0 125.69 75.757 0 TRUE FALSE FALSE 71.56930084 0 0 0 0 113.3956693 0 164.0123024 67.44664663 0 0 RSDLDLGYEPEGSAS(ph)PTPPYLK ddPTM_HeLa_Curcumin_4h_R1 2 RSDLDLGYEPEGSASPTPPYLK 22 1 O15169-2;O15169 O15169-2 AXIN1 Axin-1 1 0 RSDLDLGYEPEGS(0.024)AS(0.91)PT(0.066)PPYLK;RSDLDLGYEPEGS(0.332)AS(0.658)PT(0.01)PPYLK ; 106.73 1.85E-05 20222000 6626.3 5200.3 4975 5875.4 5503.6 7378.4 4985.4 3019.08 6954.6 6027.6 TRUE FALSE FALSE 6101.821363 5649.79076 5159.377876 5851.089152 5437.973165 5848.036668 5125.276906 3939.583594 6191.69778 6237.058651 0.978317137 0.905842173 0.827213301 0.938116744 0.871881037 0.937627333 0.821745825 0.631641261 0.992727201 1 12.60665011 -2.756383022 0.330352442 0.991517801 3.05E-27 0.699448925 0.057749521 7.029511172 0.251207928 0.02002686 3.438698734 0.001752334 2.756383022 -0.991517801 RSDS(ph)LLSFR ddPTM_HeLa_Curcumin_4h_R1 1 RSDSLLSFR 9 1 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 0 RS(0.322)DS(0.678)LLSFR 74.392 0.018636 61394000 3028 2373.4 2414.9 2674.1 2695 3652.8 3086.3 2157.2 3000.2 2739.9 TRUE FALSE FALSE 2788.330605 2578.54612 2504.398318 2663.035283 2662.863885 2895.168104 3172.893272 2814.920349 2671.085566 2835.111321 0.983499513 0.909504364 0.883350964 0.939305368 0.939244913 1.021183219 1.119142394 0.992878244 0.942144863 1 11.46918967 -5.004946891 24.3440255 0.970551791 1.05954845 0.424870797 0.048088856 133.641948 657682.4253 0.007401911 0.021346287 9.89E-06 5.004946891 0.088996658 RSDS(ph)PEIPFQAAAGPSDGLDAS(ph)SPGNSFVGLR ddPTM_HeLa_Curcumin_4h_R1 1 RSDSPEIPFQAAAGPSDGLDASSPGNSFVGLR 32 1 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 RS(0.253)DS(0.747)PEIPFQAAAGPS(0.003)DGLDAS(0.502)S(0.442)PGNS(0.053)FVGLR 71.583 1.66E-05 4776400 431.91 280.03 282.58 396 313.75 382.15 281.22 366.55 293.9 371.29 TRUE FALSE FALSE 397.7238678 304.2345454 293.0526634 394.3614569 310.0087362 302.8877823 289.1102763 478.3094076 261.6599053 384.1922999 1.03522082 0.791880903 0.762775994 1.026468925 0.806910332 0.788375463 0.7525145 1.244973956 0.681064939 1 8.585684794 -7.277392013 24.39770482 1.016632059 0.871490208 0 0.178920721 707.4297391 1081929.598 0.023013923 0.026364554 5.28E-08 7.277392013 -0.145141851 RSDS(ph)PEIPFQAAAGPSDGLDASSPGNSFVGLR ddPTM_HeLa_Curcumin_4h_R1 3 RSDSPEIPFQAAAGPSDGLDASSPGNSFVGLR 32 1 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 RS(0.128)DS(0.872)PEIPFQAAAGPSDGLDASSPGNSFVGLR;RS(0.106)DS(0.894)PEIPFQAAAGPSDGLDASSPGNSFVGLR;RS(0.221)DS(0.779)PEIPFQAAAGPSDGLDASSPGNSFVGLR ;; 99.928 2.32E-09 240830000 5398.7 3798 4525.6 4334.4 4067.8 6107.2 4836.4 2668.15 5455.2 4821.9 TRUE FALSE FALSE 4971.387198 4126.282196 4693.322717 4316.465401 4019.294142 4840.497878 4972.096367 3481.656652 4856.778208 4989.460666 0.996377671 0.826999644 0.940647303 0.865116631 0.805556835 0.970144511 0.996519804 0.697802205 0.973407455 1 12.28466816 -7.280522398 23.05509859 0.998289474 0.880244078 0.296561403 0.082342827 248.0798969 299716.2125 0.013080906 0.014975755 5.24E-08 7.280522398 -0.118045396 RSDS(ph)VSASER ddPTM_HeLa_Curcumin_4h_R1 2 RSDSVSASER 10 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 RS(0.004)DS(0.97)VS(0.026)ASER;RSDS(0.787)VS(0.213)AS(0.001)ER ; 115.37 0.0025159 132570000 7508.3 5656.1 6303.1 5765.4 6573.6 7604.8 6895.6 13177.1 6557 7482.1 TRUE FALSE FALSE 6914.010132 6144.988081 6536.698431 5741.544302 6495.214113 6027.478756 7089.071977 17194.73713 5837.713505 7742.102418 0.893040386 0.793710513 0.844305342 0.741600148 0.838947067 0.778532552 0.915652053 2.220938991 0.754021736 1 12.91850968 -4.261639613 7.201225497 0.8962413 2.238223842 0.951919978 0.092341653 0.017810099 7.698890326 0.014360137 0.115926082 5.47E-05 4.261639613 1.341982541 RSDSASS(ph)EPVGIYQGFEK ddPTM_HeLa_Curcumin_4h_R1 1 RSDSASSEPVGIYQGFEK 18 1 Q05655;Q05655-2 Q05655 PRKCD Protein kinase C delta type;Protein kinase C delta type regulatory subunit;Protein kinase C delta type catalytic subunit 1 0 RS(0.106)DS(0.056)AS(0.077)S(0.761)EPVGIYQGFEK 61.537 0.012181 6618400 2202.7 1421.3 1983.4 2001.8 1710.8 3123.4 2124.4 1740.7 2310.9 2003.9 TRUE FALSE FALSE 2028.353971 1544.150839 2056.906549 1993.517082 1690.399827 2475.571632 2184.004946 2271.431417 2057.400052 2073.535376 0.978210449 0.744694716 0.991980447 0.961409728 0.815225941 1.193889268 1.053275952 1.095438951 0.992218448 1 11.01787695 -5.247337604 24.99985155 0.958573179 1.10810884 0.451275424 0.090097615 682.3010838 1209592.375 0.012876357 0.03264614 5.66E-06 5.247337604 0.149535661 RSDVQEESEGS(ph)DTDDNKDS(ph)AAFEDNEVQDEFLEK ddPTM_HeLa_Curcumin_4h_R1 1 RSDVQEESEGSDTDDNKDSAAFEDNEVQDEFLEK 34 2 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 2 0 RS(0.11)DVQEES(0.256)EGS(0.574)DT(0.401)DDNKDS(0.659)AAFEDNEVQDEFLEK 47.162 0.0064648 11128000 1687.4 1292 1820.9 1987.9 1751.9 2114.6 1598 812.16 1741.7 1532.4 TRUE FALSE FALSE 1553.840509 1403.674723 1888.384156 1979.674597 1731.009737 1676.008124 1642.835579 1059.783845 1550.639868 1585.650786 0.979938662 0.885235725 1.190920581 1.248493435 1.091671478 1.056984387 1.036063926 0.668358919 0.977920158 1 10.63085936 -4.260561119 24.03181352 1.027338507 0.668358731 0.544085784 0.103146428 28.86610103 789624.6835 0.015502058 0.125408834 5.49E-05 4.260561119 -0.358979776 RSEACPCQPDSGS(ph)PLPAEEEK ddPTM_HeLa_Curcumin_4h_R1 1 RSEACPCQPDSGSPLPAEEEK 21 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 RSEACPCQPDS(0.148)GS(0.852)PLPAEEEK 67.388 0.0017857 19187000 1621.9 1672.8 1572.3 1675.4 1369.9 1603.1 1424.2 1065.7 1808.2 1443.4 TRUE FALSE FALSE 1493.524904 1817.389378 1630.570821 1668.467639 1353.564837 1270.598989 1464.159219 1390.627024 1609.844984 1493.558043 0.999977812 1.216818715 1.091735825 1.11710934 0.906268654 0.850719526 0.98031625 0.931083349 1.077859004 1 10.54453759 -5.735448236 24.92353551 1.033023897 0.916871298 0.472532372 0.075634999 210.3268221 201686.3898 0.012267647 0.024528844 1.84E-06 5.735448236 -0.116152599 RSECNMCNT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 RSECNMCNTPK 11 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 RS(0.005)ECNMCNT(0.995)PK 78.615 0.015391 10267000 4575.6 3390.1 3080.3 3738.4 4299.2 7663.3 6562.2 2294.6 4334 2525.6 TRUE FALSE FALSE 4213.436432 3683.125138 3194.458628 3722.931491 4247.934848 6073.845197 6746.317671 2994.212977 3858.571043 2613.364412 1.612265175 1.409342349 1.222354836 1.42457419 1.625465943 2.324147818 2.581468409 1.145731136 1.476476463 1 11.3516926 -6.804663533 0.079640329 9.48E-10 3.151525718 0.188068808 0.429940213 17.78835359 0.904059002 15.64299092 19.14031838 1.57E-07 6.804663533 3.151525717 RSECNMCNTPK ddPTM_HeLa_Curcumin_4h_R1 1 RSECNMCNTPK 11 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 0 0 72.958 0.020108 660960 515.28 389.39 346.23 344.31 487.19 525.78 511.77 323.9 636.01 599 FALSE FALSE TRUE 474.4950443 423.0471365 359.0615884 342.8853365 481.3805774 416.7273012 526.1288888 422.6556189 566.2412942 619.8152054 0.765542762 0.682537525 0.579304259 0.553205751 0.776651772 0.672341204 0.848847986 0.681905857 0.913564703 1 9.275694338 -8.507118196 0.744312261 0.985548484 0.688160648 0.600761612 0.085473644 0.291710135 0.334018443 0.042782379 0.020327683 3.11E-09 8.507118196 -0.297387837 RSEDES(ph)ETEDEEEKSQEDQEQK ddPTM_HeLa_Curcumin_4h_R1 1 RSEDESETEDEEEKSQEDQEQK 22 2 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 0 RS(0.081)EDES(0.717)ET(0.202)EDEEEKS(0.001)QEDQEQK 46.15 0.012696 151480000 773.55 585.36 702.7 664.36 618.52 552.14 339.85 557.82 570.45 383.8 TRUE FALSE FALSE 712.3227013 635.9559101 728.7426802 661.6110544 611.144553 437.6199401 349.3852763 727.8967501 507.8730622 397.1370214 1.793644669 1.601351362 1.834990547 1.665951595 1.538875804 1.101936905 0.879760026 1.832860476 1.278835855 1 8.633493046 -2.512835598 10.79256736 1.426182038 1.311809624 0 0.342851003 0 0 0.053221208 0 0.003070184 2.512835598 -0.114372414 RSEPQPEEGS(ph)PAGGQK ddPTM_HeLa_Curcumin_4h_R1 3 RSEPQPEEGSPAGGQK 16 1 F8WE91;Q9Y6K1-3;Q9Y6K1 F8WE91 DNMT3A DNA (cytosine-5)-methyltransferase 3A 1 0 RSEPQPEEGS(1)PAGGQK;RSEPQPEEGS(1)PAGGQK;RSEPQPEEGS(1)PAGGQK ;; 161.59 0.00011837 12232000 10561.8 9104.2 9008.1 9641.6 9366.8 11255.3 8333.7 5424.7 11231.8 10802.3 TRUE FALSE FALSE 9725.822385 9891.12648 9341.94811 9601.705614 9255.107028 8920.823907 8567.521193 7078.666058 9999.699641 11177.67912 0.870111074 0.884899841 0.835768142 0.85900709 0.82799899 0.798092682 0.766484804 0.633285853 0.894613232 1 13.44833304 -1.453865504 0.121020022 1.058559916 7.28E-15 0.784870747 0.041957535 19.73179654 0.182467372 0.15753782 3.490193492 0.035166933 1.453865504 -1.058559916 RSES(ph)PPAELPSLR ddPTM_HeLa_Curcumin_4h_R1 1 RSESPPAELPSLR 13 1 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 0 RS(0.235)ES(0.765)PPAELPSLR 145.79 0.00034602 13436000 2153.8 1865.8 1726.5 2438.2 2361.5 2795.2 2226.2 1379.3 2360.8 2203.1 TRUE FALSE FALSE 1983.324457 2027.071438 1790.485609 2428.111374 2333.340655 2215.444012 2288.66118 1799.84222 2101.826146 2279.657561 0.870009817 0.889199971 0.78541867 1.065121102 1.023548753 0.971831932 1.003949549 0.789523063 0.921992049 1 11.15460141 -6.213340467 24.99998987 0.922118624 0.975625123 0.126301594 0.086202236 901.4369545 468532.3631 0.014068945 0.023330684 6.12E-07 6.213340467 0.0535065 RSGPTDDGEEEMEEDTVTNGS ddPTM_HeLa_Curcumin_4h_R1 1 RSGPTDDGEEEMEEDTVTNGS 21 1 P09661 P09661 SNRPA1 U2 small nuclear ribonucleoprotein A 0 0 65.038 0.0058078 0 1415.9 1318.2 1041.1 1374.4 1609.9 1442.5 1124.8 1305.1 1455 1282.2 FALSE FALSE TRUE 1303.830021 1432.139334 1079.684082 1368.713097 1590.702994 1143.30924 1156.358861 1703.018982 1295.39014 1326.756355 0.982720012 1.079429037 0.813777208 1.031623547 1.198941304 0.861732628 0.871568361 1.283595874 0.976358723 1 10.37368774 -6.034135758 24.99192402 0.984639328 1.038211378 0.070988304 0.135443516 1876.051457 1373516.352 0.01928138 0.031984793 9.24E-07 6.034135758 0.05357205 RSGSGYEGS(ph)TS(ph)WK ddPTM_HeLa_Curcumin_4h_R1 1 RSGSGYEGSTSWK 13 1 P0C7M8 P0C7M8 CLEC2L C-type lectin domain family 2 member L 2 0 RS(0.001)GS(0.005)GY(0.138)EGS(0.852)T(0.005)S(0.998)WK 64.121 0.01833 5527300 788.46 698.08 916.48 718.47 844.64 1007.3 849.23 824.76 1245.7 958.95 TRUE FALSE FALSE 726.052559 758.4189246 950.445555 715.4971615 834.5682197 798.3746254 873.0571082 1076.225527 1109.049827 992.2734411 0.73170613 0.764324523 0.957846412 0.72106854 0.841066772 0.804591348 0.879855362 1.084605798 1.117685691 1 9.954593929 -4.271373977 4.009027546 0.851887924 1.103280265 0.21630356 0.120602937 0.2331706 7.809349368 0.015661731 0.167069142 5.35E-05 4.271373977 0.251392341 RSHSPSPSS(ph) ddPTM_HeLa_Curcumin_4h_R1 1 RSHSPSPSS 9 1 Q5SV97-2;Q5SV97-3;Q5SV97 Q5SV97-2 PERM1 PGC-1 and ERR-induced regulator in muscle protein 1 1 0 RSHS(0.001)PSPS(0.1)S(0.898) 45.081 0.01825 1276300 475.46 457.59 393 422.22 317.09 478.2 453.92 247.07 399.33 360.13 TRUE FALSE FALSE 437.8268393 497.1420406 407.5649257 420.4729655 313.3089088 379.0159296 466.6557735 322.4005056 355.5244981 372.6444907 1.174918321 1.334092018 1.093709785 1.128348804 0.840771611 1.017097902 1.252281424 0.865169119 0.954058109 1 8.54165612 RSLPSTSSTSSTK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 RSLPSTSSTSSTKR 14 2 A0A590UJA3;S4R3W2;A0A590UJU2;A0A590UK38;A0A590UK73;B1AKN7;B1AKN5;A0A590UK09;B1AKN8;Q12857-2;Q12857-3;Q12857;Q12857-4 A0A590UJA3 NFIA Nuclear factor 1;Nuclear factor 1 A-type 0 1 RSLPSTSSTSSTK(1)R 94.454 0.0028727 959310 0 0 0 0 67.052 0 69.096 0 188.49 0 FALSE TRUE FALSE 0 0 0 0 66.25244869 0 71.0346478 0 167.8131186 0 0 RSLS(ph)PILPGR ddPTM_HeLa_Curcumin_4h_R1 1 RSLSPILPGR 10 1 A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-1;M0QZS0;A0A590UK10;Q6ZSZ5-2;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 A0A3B3IPE9 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 0 RS(0.02)LS(0.98)PILPGR 81.709 0.013922 9379800 1302.4 807.41 999.35 1090.2 899.7 1396.1 988.3 977.97 1078.7 1177.6 TRUE FALSE FALSE 1199.313666 877.1989227 1036.38679 1085.689041 888.9716651 1106.533123 1016.029038 1276.148551 960.3693088 1218.521512 0.98423676 0.719887925 0.850528103 0.890988817 0.729549422 0.90809486 0.833821174 1.04729259 0.788143089 1 10.25091601 -7.443079096 14.7221548 0.993048051 0.852035799 0 0.108452558 1.804045715 331.8556978 0.013892475 0.015882319 3.61E-08 7.443079096 -0.141012252 RSLS(ph)PQEDALTGSR ddPTM_HeLa_Curcumin_4h_R1 1 RSLSPQEDALTGSR 14 1 Q96EN8 Q96EN8 MOCOS Molybdenum cofactor sulfurase 1 0 RS(0.017)LS(0.983)PQEDALTGSR 105.63 0.0057272 7232900 1504.6 1582.7 1096.3 1176.5 1264.1 1631.3 1179.3 1133.6 1916.8 1785.6 TRUE FALSE FALSE 1385.509322 1719.501536 1136.929842 1171.631955 1249.026433 1292.949991 1212.387984 1479.229422 1706.531836 1847.649467 0.74987672 0.930642725 0.615338495 0.634120257 0.676008331 0.699781 0.656178569 0.800600681 0.923623158 1 10.85147536 -9.067897829 0.365315557 1.085444906 0.680783262 0.576224851 0.085556804 1.155252366 0.226527762 0.188202484 0.035607346 8.55E-10 9.067897829 -0.404661644 RSNS(ph)TTQVSQPR ddPTM_HeLa_Curcumin_4h_R1 2 RSNSTTQVSQPR 12 1 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 0 RS(0.01)NS(0.754)T(0.231)T(0.005)QVSQPR;RS(0.011)NS(0.898)T(0.09)TQVSQPR ; 171.81 6.28E-05 20588600 499.38 644.39 742.64 765.99 547.58 706.92 545.85 689.87 527.7 748.24 TRUE FALSE FALSE 459.8535461 700.0882003 770.1628917 762.8205363 541.0504661 560.2968234 561.1650819 900.2081872 469.8126302 774.2412843 0.593940875 0.904224838 0.994732401 0.98524911 0.698813764 0.723672109 0.724793541 1.162697218 0.606803899 1 9.596639427 -4.251392839 24.04310901 0.818201421 1.162697546 0.335166991 0.15047087 895.3139119 2142566.239 0.024166922 0.421124552 5.61E-05 4.251392839 0.344496124 RSNVSSPAT(ph)PTASSSSSTTPTR ddPTM_HeLa_Curcumin_4h_R1 1 RSNVSSPATPTASSSSSTTPTR 22 1 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 RSNVSSPAT(0.949)PT(0.011)AS(0.002)S(0.001)S(0.001)S(0.002)S(0.001)T(0.009)T(0.011)PT(0.014)R 68.386 0.0014358 1827100 554.85 458.82 573.15 420.96 345.19 530.23 535.43 318.75 405.76 446.1 TRUE FALSE FALSE 510.933037 498.4783563 594.3914432 419.2181791 341.0738347 420.2543211 550.4527248 415.9354077 361.2491432 461.6019418 1.106869341 1.07988791 1.28767102 0.908181143 0.738891681 0.910425809 1.192483555 0.90106945 0.782598838 1 8.850505483 RSNVSSPATPTAS(ph)SSSSTTPTR ddPTM_HeLa_Curcumin_4h_R1 1 RSNVSSPATPTASSSSSTTPTR 22 1 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 RSNVSSPATPT(0.02)AS(0.401)S(0.269)S(0.024)S(0.035)S(0.035)T(0.096)T(0.096)PT(0.024)R 88.829 0.0001913 4665400 730.36 526.76 487.57 445.68 813.25 824.91 446.47 418.21 923.47 614.15 TRUE FALSE FALSE 672.5512353 572.2907872 505.6397731 443.8358942 803.5525249 653.8143673 458.9967466 545.7203038 822.1676514 635.4916668 1.058316372 0.900548059 0.795667039 0.698413398 1.264458005 1.028832322 0.722270284 0.858737152 1.293750484 1 9.311729397 -7.250722187 21.9237175 1.027538284 0.896785342 0.205020811 0.175125055 213.262692 436260.8039 0.026301021 0.03198018 5.61E-08 7.250722187 -0.130752942 RSNVSSPATPTASSSSST(ph)TPTR ddPTM_HeLa_Curcumin_4h_R1 2 RSNVSSPATPTASSSSSTTPTR 22 1 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 RSNVSSPATPTAS(0.011)S(0.071)S(0.071)S(0.107)S(0.107)T(0.28)T(0.28)PT(0.071)R;RSNVSSPAT(0.001)PT(0.004)AS(0.039)S(0.034)S(0.034)S(0.112)S(0.112)T(0.323)T(0.256)PT(0.084)R ; 86.997 0.00026307 5103100 1185.32 886.84 823.11 640.17 915.21 1217.82 784.22 557.48 925.27 1239.86 TRUE FALSE FALSE 1091.500671 963.4944979 853.6151807 637.5211462 904.2967185 965.2304043 806.2231026 727.4530857 823.7701959 1282.945043 0.850777418 0.75100216 0.665355999 0.496920074 0.704860059 0.752355223 0.62841593 0.56701812 0.642093128 1 10.32524366 -7.445675748 0.8380173 0.965371107 0.631620688 0.176263102 0.123898919 0.177547269 0.257828489 0.019427741 0.020736327 3.58E-08 7.445675748 -0.33375042 RSPQQTVPYVVPLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 RSPQQTVPYVVPLSPK 16 1 Q9UQR0;H0Y6S1;B4DRC2 Q9UQR0 SCML2 Sex comb on midleg-like protein 2 1 0 RSPQQTVPYVVPLS(1)PK;RSPQQTVPYVVPLS(1)PK;RSPQQTVPYVVPLS(1)PK ;; 117.6 0.00050984 141188000 7438.39 7813.1 6564.66 7322.48 6828.8 8630.07 6436.34 4621.14 7830.13 7337.41 TRUE FALSE FALSE 6849.633583 8488.42955 6807.952074 7292.181518 6747.37102 6840.096201 6616.926378 6030.104313 6971.184329 7592.384451 0.902171594 1.118018931 0.896681684 0.960459993 0.888702497 0.900915417 0.871521512 0.794230634 0.918181156 1 12.89033733 -2.351115179 0.414653637 0.966619453 7.40E-19 0.438582199 0.061498512 15.90734385 0.535652274 0.014777921 10.77194344 0.004455381 2.351115179 -0.966619453 RSPS(ph)PGS(ph)QGPAGSGR ddPTM_HeLa_Curcumin_4h_R1 1 RSPSPGSQGPAGSGR 15 1 Q9Y5B0-4 Q9Y5B0-4 CTDP1 RNA polymerase II subunit A C-terminal domain phosphatase 2 0 RS(0.102)PS(0.909)PGS(0.986)QGPAGS(0.003)GR 46.746 0.017188 16149000 1796.6 1309.8 1375.1 1764.9 1671.8 2041.1 1374.1 1091.9 2112.6 1348.7 TRUE FALSE FALSE 1654.397214 1423.013276 1426.062416 1757.597311 1651.864877 1617.752852 1412.653548 1424.815284 1880.853065 1395.567225 1.185465798 1.019666592 1.021851467 1.259414294 1.183651241 1.159208115 1.012243282 1.020957829 1.347733762 1 10.44663591 -9.579199636 1.352283622 0.999778358 1.118422427 0 0.136803088 0.587809786 1.921481275 0.063561349 0.014720273 2.64E-10 9.579199636 0.118644069 AYILVT(ph)PLK ddPTM_HeLa_Curcumin_4h_R1 2 AYILVTPLK 9 0 Q6P0N0 Q6P0N0 MIS18BP1 Mis18-binding protein 1 1 0 AYILVT(1)PLK;AYILVT(1)PLK ; 121.6 0.016872 83322000 10191.5 6614.9 8648.5 9794.4 9260.2 12505.6 8849.3 1176.17 11353 9637.8 TRUE FALSE FALSE 9384.832021 7186.662481 8969.021018 9753.873368 9149.778163 9911.797593 9097.587541 1534.778819 10107.6043 9972.712833 0.941051064 0.72063265 0.89935619 0.978056175 0.917481363 0.993891808 0.912248021 0.153897825 1.013526056 1 13.28377029 -4.261836644 5.302317512 0.946380673 0.121522094 0.89336975 0.080431838 0.035347636 3.502500509 0.011567622 0.105717046 5.47E-05 4.261836644 -0.824858579 down RSPSAPAATSSASSSTSSYK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 RSPSAPAATSSASSSTSSYKR 21 2 A0A087X0S7;A0A0C4DH00;A0A087WTU1;A0A0B4J2G4;Q15345-3;Q15345 A0A087X0S7 LRRC41 Leucine-rich repeat-containing protein 41 0 1 RSPSAPAATSSASSSTSSYK(1)R 157.02 3.25E-05 1277400 229.43 271.9 410.6 250.21 198.76 461.91 222.52 275.24 395.42 458 FALSE TRUE FALSE 211.2703734 295.4018244 425.8171972 249.1746973 196.3899168 366.1046592 228.7633123 359.159409 352.0434153 473.9154659 0.445797592 0.623321765 0.898508759 0.525778784 0.414398624 0.77251047 0.482709109 0.757855429 0.742840107 1 8.888485933 -9.460936605 1.157116688 1.003345671 0.599262772 0.219367634 0.167212768 0.330613344 0.781351535 0.108360337 0.025893777 3.46E-10 9.460936605 -0.404082898 RSPT(ph)DSDVSLDSEDSGAK ddPTM_HeLa_Curcumin_4h_R1 1 RSPTDSDVSLDSEDSGAK 18 1 Q8N3V7-2 Q8N3V7-2 SYNPO Synaptopodin 1 0 RS(0.25)PT(0.732)DS(0.017)DVSLDSEDSGAK 133.17 0.00013373 24750000 3950.8 3005.8 3655.9 3704.5 3896.2 5196.7 3567.2 2812.6 4185.7 3175.2 TRUE FALSE FALSE 3638.090011 3265.607958 3791.39087 3689.171761 3849.74036 4118.845841 3667.286031 3670.148792 3726.539182 3285.537964 1.107304208 0.993934021 1.153963495 1.122851661 1.171722988 1.253629052 1.11619043 1.117061752 1.134224965 1 11.6819139 -6.739962372 23.57740339 1.047831956 1.157757004 0.422493798 0.054951562 82.02162852 90042.54726 0.008872329 0.01253858 1.82E-07 6.739962372 0.109925048 RSPTS(ph)SPTPQR ddPTM_HeLa_Curcumin_4h_R1 1 RSPTSSPTPQR 11 1 A0A0D9SFB1;A0A0U1RQP1;A0A0D9SFE4;Q05193-5;Q05193-3;Q05193-2;Q05193 A0A0D9SFB1 DNM1 Dynamin-1 1 0 RSPT(0.004)S(0.882)S(0.113)PT(0.001)PQR 86.803 0.0097562 697080 384.54 290.91 118.85 210.59 208.58 500.97 362.42 464.07 395.7 350.5 TRUE FALSE FALSE 354.1032532 316.0549641 123.2546856 209.7186344 206.0928197 397.0631749 372.5885298 605.5628067 352.2927 362.6798489 0.976352158 0.87144341 0.339844317 0.578247275 0.568249988 1.094803519 1.027320737 1.669689696 0.971360005 1 8.502552779 -7.250394903 5.605349153 0.9891199 0.847898348 0.01368311 0.343275591 0.56892652 66.21859368 0.060294043 0.07199947 5.62E-08 7.250394903 -0.141221551 RSQS(ph)IEQESQEK ddPTM_HeLa_Curcumin_4h_R1 4 RSQSIEQESQEK 12 1 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 0 RSQS(1)IEQESQEK;RS(0.012)QS(0.988)IEQESQEK;RS(0.013)QS(0.982)IEQES(0.005)QEK;RSQS(1)IEQESQEK ;;; 177.39 1.84E-06 4061900 11174.2 9751.84 10207.2 10855.5 10340.7 10054.1 7269.6 5082.66 11413.5 9566 TRUE FALSE FALSE 10289.75028 10594.7456 10585.48781 10810.58282 10217.39391 7968.766327 7473.565411 6632.339636 10161.46761 9898.417788 1.039534853 1.070347385 1.069412106 1.09215261 1.03222496 0.805054555 0.755026265 0.670040382 1.026574936 1 13.27298222 -5.119917026 2.544416269 1.034176982 0.71362317 0.946311044 0.033508018 0.055824935 0.695687659 0.005872881 0.018654201 7.59E-06 5.119917026 -0.320553812 RSS(ph)DGS(ph)LSHEEDLAK ddPTM_HeLa_Curcumin_4h_R1 1 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;H0YEF9;E9PJZ7 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 2 0 RS(0.345)S(0.83)DGS(0.719)LS(0.107)HEEDLAK 59.709 0.019217 10643000 3929.5 3426.4 3342.2 3638.5 3361.3 4598 3099.1 1528.3 4644.8 3525.1 TRUE FALSE FALSE 3618.475929 3722.562748 3466.064872 3623.444851 3321.218693 3644.32297 3186.052405 1994.271635 4135.277061 3647.596963 0.992016378 1.020552102 0.950232415 0.993378624 0.910522387 0.999102425 0.873466131 0.546735743 1.133699009 1 11.83273061 -4.214136116 1.953801992 0.989278396 0.375890256 0.860514394 0.054975407 0.12756315 0.459926595 0.004199366 0.146064149 6.11E-05 4.214136116 -0.613388141 RSS(ph)DGSLS(ph)HEEDLAK ddPTM_HeLa_Curcumin_4h_R1 1 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;H0YEF9;E9PJZ7 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 2 0 RS(0.115)S(0.883)DGS(0.444)LS(0.557)HEEDLAK 63.69 0.016254 112620000 2531.6 2669.8 2635.1 2717.3 2851.4 3426.1 2261.1 1736.9 3498.1 2968.7 TRUE FALSE FALSE 2331.221189 2900.565616 2732.759124 2706.056533 2817.398917 2715.48824 2324.540381 2266.472814 3114.367182 3071.862104 0.758895129 0.944236921 0.88960996 0.88091732 0.917163213 0.883987675 0.756720289 0.737817238 1.013836909 1 11.58489774 -9.549613422 1.29924947 1.000529363 0.840991025 0.462150803 0.068789842 0.38385165 1.15457291 0.054159691 0.012644687 2.82E-10 9.549613422 -0.159538339 RSS(ph)DGSLSHEEDLAK ddPTM_HeLa_Curcumin_4h_R1 2 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;H0YEF9;E9PJZ7 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 0 RS(0.33)S(0.63)DGS(0.035)LS(0.006)HEEDLAK;RS(0.182)S(0.813)DGS(0.003)LS(0.001)HEEDLAK ; 79.885 0.0074618 55992000 5371.8 4242.17 4094.18 4041.9 5817.53 7509 4478.74 2741.06 6046.8 4102.35 TRUE FALSE FALSE 4946.616362 4608.844272 4245.913912 4025.175689 5748.159754 5951.548756 4604.40139 3576.796576 5383.481168 4244.906357 1.165306357 1.085735205 1.000237356 0.948236628 1.354131109 1.40204477 1.084688566 0.842609065 1.26822142 1 12.05151701 -5.779564398 24.99384851 1.065919074 1.181225388 0.065660323 0.16623579 434.857017 599654.0394 0.024165482 0.043865882 1.66E-06 5.779564398 0.115306313 YSS(ph)QDADEQDWEFQKR ddPTM_HeLa_Curcumin_4h_R1 1 YSSQDADEQDWEFQKR 16 1 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 YS(0.042)S(0.958)QDADEQDWEFQKR 98.804 0.0015088 16992000 1202.3 975.24 1253.1 1062.5 933.56 1603.3 1616.4 2654.1 1238.3 1182.4 TRUE FALSE FALSE 1107.136686 1059.5354 1299.540988 1058.103657 922.4279067 1270.757507 1661.751834 3463.322872 1102.461588 1223.488312 0.904901727 0.865995523 1.062160525 0.864825308 0.753932749 1.038634775 1.35820818 2.830695511 0.901080605 1 10.2567846 -4.20378833 2.032404 0.937249108 3.56548007 0.978141 0.085585232 0.089237104 0.348269956 0.012709619 0.4547048 6.25E-05 4.20378833 2.628230962 up RSS(ph)FLNAK ddPTM_HeLa_Curcumin_4h_R1 1 RSSFLNAK 8 1 A0A2R8YGD3;Q9Y4G8;A0A2R8Y661;H0Y8T6 A0A2R8YGD3 RAPGEF2 Rap guanine nucleotide exchange factor 2 1 0 RS(0.094)S(0.906)FLNAK 96.171 0.0081054 47845000 2477.6 2190.7 2097.7 2582.9 2348.9 2704.7 2323.6 1407.1 2813.5 2612.8 TRUE FALSE FALSE 2281.495346 2380.054346 2175.442607 2572.212644 2320.890902 2143.714732 2388.793962 1836.118313 2504.866089 2703.594606 0.843874796 0.880329596 0.804648228 0.951404711 0.858446343 0.792912786 0.883562187 0.679139657 0.926494706 1 11.40066313 -13.52287875 0.14333082 1.581842825 0.776171476 0.404073053 0.066334462 42.55615355 0.42152827 7.023922421 0.163889435 3.00E-14 13.52287875 -0.805671348 RSS(ph)FSEGQTLTVTSGAK ddPTM_HeLa_Curcumin_4h_R1 1 RSSFSEGQTLTVTSGAK 17 1 H7C3H3;E9PEM3;H7C357;H0Y6E6;Q92622-3;Q92622-2;Q92622 H7C3H3 KIAA0226 Run domain Beclin-1 interacting and cysteine-rich containing protein 1 0 RS(0.104)S(0.895)FS(0.001)EGQTLTVTSGAK 120.08 0.00033697 0 1273 849.91 1189.8 1257.1 1160.1 1489.1 827.7 640.88 1235.2 973.03 TRUE FALSE FALSE 1172.240707 923.3724333 1233.895035 1251.898453 1146.266565 1180.243874 850.9230344 836.2813618 1099.70165 1006.84272 1.164273906 0.917096995 1.225509218 1.243390282 1.138476291 1.172222683 0.845139978 0.830597813 1.092227841 1 9.975622621 -4.750269844 24.56589535 1.099490882 0.837868644 0.575972641 0.095351323 109.8348524 241560.9034 0.014699158 0.053935348 1.78E-05 4.750269844 -0.261622238 RSS(ph)GFISELPSEEGK ddPTM_HeLa_Curcumin_4h_R1 1 RSSGFISELPSEEGK 15 1 Q5VZK9;Q5VZK9-2;A0A0U1RQQ1 Q5VZK9 LRRC16A Leucine-rich repeat-containing protein 16A 1 0 RS(0.242)S(0.758)GFISELPSEEGK 117.53 0.0023775 14810000 3385.6 2476.4 2843 2898.4 3099.3 2944.8 2375.7 1476.2 3076.6 2765.5 TRUE FALSE FALSE 3117.626188 2690.448981 2948.364081 2886.407189 3062.342872 2334.015285 2442.355748 1926.286584 2739.104677 2861.600919 1.089469243 0.940190144 1.030319798 1.008668668 1.070150226 0.8156327 0.853492789 0.673149974 0.957193108 1 11.48260677 -4.715054145 1.02890294 1.035727073 0.642154627 0.743712128 0.062015389 0.320618334 0.416802703 0.009021148 0.115742525 1.93E-05 4.715054145 -0.393572445 GSPATS(ph)PHLGR ddPTM_HeLa_Curcumin_4h_R1 1 GSPATSPHLGR 11 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 0 GSPAT(0.052)S(0.947)PHLGR 78.964 0.013719 5011400 1416.3 1232.9 1241.6 1576.3 1465.2 1660.3 1023.2 327.1 1761.3 1460.6 TRUE FALSE FALSE 1304.198361 1339.466382 1287.614788 1569.777688 1447.728447 1315.935065 1051.908238 426.8312842 1568.089797 1511.355741 0.862932746 0.886268101 0.8519601 1.038655325 0.957900518 0.870698426 0.696003072 0.28241616 1.037538518 1 10.56162757 -4.261608473 1.597366405 0.932859662 0.03749528 0.907567007 0.064684473 0.230341378 0.544722355 0.009856369 0.320033205 5.48E-05 4.261608473 -0.895364382 down RSS(ph)LLNAK ddPTM_HeLa_Curcumin_4h_R1 2 RSSLLNAK 8 1 E9PCH4;Q8TEU7;Q8TEU7-4;A0A5F9ZHG7;B7Z7Y1;Q8TEU7-2;Q8TEU7-5;Q8TEU7-3;D6RE77 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 0 RS(0.002)S(0.998)LLNAK;RSS(1)LLNAK ; 119.34 0.013361 130729000 10309.4 7297.7 8566.9 9575.5 9105.8 9402.2 7228 4771 8735.7 8428 TRUE FALSE FALSE 9493.400112 7928.48067 8884.39685 9535.879118 8997.219282 7452.077735 7430.798227 6225.655937 7777.415566 8720.872373 1.088583768 0.909138482 1.018750931 1.093454727 1.031687989 0.854510583 0.852070516 0.71387995 0.891816235 1 13.09025674 -4.94732323 1.536571482 1.035002125 0.746361494 0.602622381 0.072695528 0.168362985 0.702803016 0.009016171 0.04940563 1.13E-05 4.94732323 -0.288640631 RSS(ph)LPSFETLDYGDEEDIETQLSSSGK ddPTM_HeLa_Curcumin_4h_R1 1 RSSLPSFETLDYGDEEDIETQLSSSGK 27 1 K7EPU8;K7EQI2;A0A0C4DGP8;K7EJF0;Q96ST8-3;Q96ST8 K7EPU8 CEP89 Centrosomal protein of 89 kDa 1 0 RS(0.239)S(0.51)LPS(0.15)FET(0.067)LDY(0.013)GDEEDIET(0.021)QLSSSGK 44.776 0.016731 7099000 1697.8 1229 1307.7 1461.9 1361.8 2165.3 1413.8 905.54 1870.2 1520.8 TRUE FALSE FALSE 1563.417338 1335.229284 1356.164512 1455.851045 1345.561424 1716.192372 1453.467423 1181.634977 1665.043739 1573.647687 0.993498959 0.848493151 0.861796782 0.925144209 0.855058877 1.090582337 0.923629498 0.750889152 1.058079107 1 10.61989687 -7.292185652 18.75776678 0.996930334 0.900884512 0.303982963 0.083500183 34.83151633 21249.64414 0.013657761 0.015623042 5.10E-08 7.292185652 -0.096045822 QISGQYSGS(ph)PQLLK ddPTM_HeLa_Curcumin_4h_R1 2 QISGQYSGSPQLLK 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GUE9;Q96N67-7 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 QISGQYS(0.24)GS(0.76)PQLLK;QISGQYS(0.011)GS(0.989)PQLLK ; 159.69 2.27E-06 23823000 3972.4 4135.3 4230.6 3871.9 3967.7 4782.6 3318.3 533.2 4010.7 3089.8 TRUE FALSE FALSE 3657.980348 4492.736905 4387.389758 3855.879104 3920.387769 3790.634849 3411.402567 695.7702254 3570.736244 3197.17032 1.144130585 1.405222886 1.372272766 1.206028681 1.226205481 1.185621806 1.06700683 0.217620632 1.116842672 1 11.64257989 -4.261521128 4.165425457 1.142432538 0.142369479 0.843126357 0.124832619 0.081982429 3.141325453 0.021864285 0.244052203 5.48E-05 4.261521128 -1.000063058 down QSS(ph)LTFQSSDPEQMR ddPTM_HeLa_Curcumin_4h_R1 1 QSSLTFQSSDPEQMR 15 0 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 0 QS(0.099)S(0.899)LT(0.001)FQSSDPEQMR 91.592 0.0079804 8789400 1535.6 1064.2 1383.2 1279.1 1214 1753.3 1862.7 4120.6 924.59 926.55 TRUE FALSE FALSE 1414.05564 1156.184706 1434.462609 1273.807423 1199.523843 1389.645816 1914.962349 5376.951971 823.1647902 958.7475435 1.47489884 1.205932379 1.496183869 1.328616101 1.251136288 1.449438724 1.997358284 5.608308472 0.858583467 1 9.905007166 -4.20302405 2.302833806 1.26593273 7.107136099 0.977889193 0.1953249 0.074967434 0.405076953 0.028487892 0.929492123 6.27E-05 4.20302405 5.841203369 up T(ph)SDANETEDHLESLICK ddPTM_HeLa_Curcumin_4h_R1 1 TSDANETEDHLESLICK 17 0 F2Z2T1;Q09161 F2Z2T1 NCBP1 Nuclear cap-binding protein subunit 1 1 0 T(0.815)S(0.185)DANETEDHLESLICK 155.08 0.00017045 16716000 2661.1 2125.7 2025.6 2148.5 2563.2 3707.5 4072.2 7293.5 2845.9 3098.7 TRUE FALSE FALSE 2450.471127 2309.436036 2100.670518 2139.610076 2532.635514 2938.522708 4186.454972 9517.254575 2533.71189 3206.379594 0.764248603 0.720262829 0.655153408 0.667297808 0.789873887 0.916461268 1.305664176 2.968224533 0.790209585 1 11.64672952 -4.201884401 2.038758119 0.833926603 3.802846486 0.973950533 0.106969388 0.127930603 0.501195146 0.020482956 0.739293134 6.28E-05 4.201884401 2.968919883 up RSS(ph)SSGDQSSDSLNSPTLLAL ddPTM_HeLa_Curcumin_4h_R1 2 RSSSSGDQSSDSLNSPTLLAL 21 1 P15408;P15408-3;P15408-2 P15408 FOSL2 Fos-related antigen 2 1 0 RS(0.082)S(0.385)S(0.385)S(0.144)GDQS(0.001)S(0.001)DS(0.001)LNSPTLLAL;RS(0.008)S(0.546)S(0.203)S(0.203)GDQS(0.029)S(0.011)DSLNSPTLLAL ; 70.987 0.004707 27369500 2403.2 1760.9 1781.97 1976.34 2401.72 2937 2787.2 1635.17 2477.4 2431.4 TRUE FALSE FALSE 2212.984184 1913.10435 1848.011376 1968.162429 2373.081058 2327.833093 2865.401331 2133.725806 2205.635418 2515.890969 0.879602579 0.76040829 0.734535558 0.782292418 0.943236844 0.925251977 1.138921108 0.848099473 0.876681639 1 11.29685369 -3.93663924 15.82083446 0.916444003 0.160997818 0 0.116467126 581399.6292 3129129.889 0.017561344 14239263.76 0.000115707 3.93663924 -0.755446185 S(ph)FVPEEEKHEER ddPTM_HeLa_Curcumin_4h_R1 1 SFVPEEEKHEER 12 1 B4DG57;O94880-2;A0A0U1RRH6;O94880 B4DG57;A0A0U1RRH6 PHF14 PHD finger protein 14 1 0 S(1)FVPEEEKHEER 70.272 0.013902 4575800 2991.8 2467.8 2955.5 3022.2 3596.8 3988.9 6204.5 12520 2655.1 2828.7 TRUE FALSE FALSE 2754.995873 2681.105636 3065.03343 3009.694937 3553.910509 3161.557176 6378.581571 16337.29037 2363.842173 2926.997114 0.941236279 0.915991896 1.047159703 1.028253469 1.214183127 1.080136759 2.179223731 5.581587452 0.807599762 1 11.51520561 -4.200543099 1.883290653 0.991120596 7.523339702 0.994233054 0.105022388 0.042773467 0.136511081 0.013340244 0.513313733 6.30E-05 4.200543099 6.532219106 up S(ph)RT(ph)GSESSQTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 0 S(0.975)RT(0.51)GS(0.51)ES(0.004)SQTGTSTTSSR 91.518 0.0039438 2284200 945.39 919.48 841.82 995.22 1005.5 1228.3 876.68 371.59 933.32 978.78 TRUE FALSE FALSE 870.5613839 998.9557541 873.0185897 991.1020433 993.5100692 973.5367342 901.2772813 484.8860804 830.9371311 1012.792532 0.859565366 0.986337994 0.861991535 0.978583483 0.980961093 0.96124004 0.889893293 0.478761508 0.820441605 1 9.984122957 -4.261487279 3.715829621 0.938879 0.429679655 0.834037621 0.060089914 0.073376942 1.888297903 0.008110884 0.102492947 5.48E-05 4.261487279 -0.509199345 down RSSSSGDQSSDSLNS(ph)PTLLAL ddPTM_HeLa_Curcumin_4h_R1 1 RSSSSGDQSSDSLNSPTLLAL 21 1 P15408;P15408-3;P15408-2 P15408 FOSL2 Fos-related antigen 2 1 0 RSSSSGDQSSDS(0.002)LNS(0.98)PT(0.018)LLAL 81.639 0.0016936 3079000 929.21 643.9 687.29 687.65 795.85 1163 672.93 592.59 1003.6 790.22 TRUE FALSE FALSE 855.662048 699.5558468 712.761572 684.8046865 786.3600085 921.7806903 691.8106047 773.2679631 893.5075909 817.6800862 1.046450883 0.855537341 0.871687576 0.837497082 0.961696416 1.127312143 0.846065125 0.945685209 1.092734929 1 9.675392695 -7.277355731 24.73078411 1.021935141 0.922334653 0.308389354 0.083813255 748.2687934 1162655.56 0.014222855 0.016292207 5.28E-08 7.277355731 -0.099600488 RST(ph)QGVTLTDLQEAEK ddPTM_HeLa_Curcumin_4h_R1 1 RSTQGVTLTDLQEAEK 16 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 RST(1)QGVTLTDLQEAEK 184.22 1.95E-23 0 2196.5 580.15 2110 2326 2303 3581.6 3413.9 2502 2120.3 3141.1 TRUE FALSE FALSE 2022.644707 630.2955809 2188.198456 2316.375628 2275.538229 2838.735787 3509.684846 3264.848282 1887.708395 3250.252991 0.622303775 0.193922006 0.673239425 0.712675485 0.70011111 0.873389178 1.079818973 1.004490509 0.580788142 1 11.6663363 -4.967946621 3.508834116 0.74318824 1.040482816 0.316691768 0.204972166 0.293905747 7.601013275 0.03521672 0.114620465 1.08E-05 4.967946621 0.297294576 S(ph)AVFPGEGK ddPTM_HeLa_Curcumin_4h_R1 1 SAVFPGEGK 9 0 A0A1B0GUN5;Q5VTI5;Q9Y2H5 A0A1B0GUN5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 0 S(1)AVFPGEGK 115 0.007534 13555000 4877.1 4382.2 4344.7 4544.2 4938.9 5910.4 3928.1 1284.3 4262.8 4454.7 TRUE FALSE FALSE 4491.072389 4760.977841 4505.718404 4525.397304 4880.006843 4684.516416 4038.311914 1675.877158 3795.181505 4609.500493 0.974307823 1.032861988 0.977485177 0.981754381 1.058684526 1.016274198 0.876084495 0.363570231 0.823338995 1 12.17039471 -4.261380003 2.736868461 0.995962818 0.24211125 0.902268469 0.060754527 0.043416824 0.432952144 0.003972481 0.073575502 5.48E-05 4.261380003 -0.753851568 down RSTSSSSDT(ph)MS(ph)T(ph)FK ddPTM_HeLa_Curcumin_4h_R1 1 RSTSSSSDTMSTFK 14 1 G5EA48;Q7Z6B7-2;Q7Z6B7 G5EA48 SRGAP1 SLIT-ROBO Rho GTPase-activating protein 1 3 0 RSTSSSS(0.002)DT(0.998)MS(1)T(1)FK 65.719 0.0079915 0 141.73 246.23 220.48 255.42 255.2 218.34 0 149.83 289.74 239.15 TRUE FALSE FALSE 130.5119209 267.513024 228.6511828 254.3631397 252.1569067 173.0538228 0 195.5124773 257.9562469 247.4604447 0.527405182 1.081033473 0.923990834 1.027894135 1.018978637 0.69931913 0 0.790075673 1.04241406 1 7.951054126 -4.985967192 24.84489814 0.840744467 0.383693022 0.401717544 0.246585245 186.1485815 329568.5718 0.036496867 0.109419754 1.03E-05 4.985967192 -0.457051445 RSTVNEK(ac)PK ddPTM_HeLa_Curcumin_4h_R1 1 RSTVNEKPK 9 2 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 0 1 RSTVNEK(1)PK 96.113 0.0031279 816390 356.87 331.08 323.23 261.39 409.92 398.91 369.09 316.77 436.24 304.6 FALSE TRUE FALSE 328.6233629 359.6970799 335.2091881 260.3084374 405.0319717 316.1715694 379.445672 413.3517148 388.3855634 315.1848273 1.042637 1.141225874 1.063532122 0.825891397 1.285061769 1.003130677 1.203883053 1.311458163 1.232247017 1 8.300054276 -1.000000186 0.5237114 1.024093585 12.18706305 0.200572897 0.128606325 74.16086092 0.668294611 0.019286806 925.9467864 0.099999957 1.000000186 11.16296946 RSVRKNHMY(ph)S(ph)CR ddPTM_HeLa_Curcumin_4h_R1 1 RSVRKNHMYSCR 12 3 B9VVT8;A0A087WXV4;P41235-7;P41235-3;P41235-6;P41235-5;P41235-2;P41235;P41235-4 B9VVT8 HNF4alpha;HNF4A Hepatocyte nuclear factor 4-alpha 2 0 RSVRKNHMY(1)S(1)CR 109.39 0.0030953 3564500 1192 1293.1 890.84 1254.7 1095.2 1425.1 1115.4 834.62 1386.8 1287.9 TRUE FALSE FALSE 1097.651942 1404.869802 923.8553141 1249.508384 1082.140455 1129.518196 1146.695122 1089.091796 1234.67151 1332.654429 0.823658345 1.054189122 0.69324447 0.937608698 0.812018804 0.847570211 0.860459469 0.817234965 0.926475373 1 10.38008701 -11.9271559 0.308332343 1.444555775 0.841973727 0.16786115 0.090392849 16.65338662 0.541362709 4.592700917 0.033440121 1.18E-12 11.9271559 -0.602582048 RSVSDNDIR ddPTM_HeLa_Curcumin_4h_R1 3 RSVSDNDIR 9 1 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 ;; ;; 126.39 0.0053135 10516300 8745.5 6540.6 7448.6 7113.2 7947 9921.9 7684.9 8304.2 8051.6 7067 FALSE FALSE TRUE 8053.284447 7105.94032 7724.651668 7083.767463 7852.237215 7863.986097 7900.517611 10836.11235 7168.359624 7312.577724 1.10129215 0.971742194 1.056351393 0.96871004 1.073798804 1.075405472 1.080401181 1.481845768 0.980278076 1 12.83616434 -4.243099641 3.36204337 1.042127976 1.549661645 0.892326914 0.046751193 0.084415697 1.512136098 0.006758366 0.112228528 5.71E-05 4.243099641 0.507533669 RSYS(ph)SPDITQAIQEEEKR ddPTM_HeLa_Curcumin_4h_R1 1 RSYSSPDITQAIQEEEKR 18 2 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 0 RS(0.071)Y(0.011)S(0.734)S(0.184)PDITQAIQEEEKR 71.434 0.0037998 6803600 1724.7 1690.3 1588.4 1710.5 1595.1 1962.1 1495.2 1698.6 1792.8 1854.2 TRUE FALSE FALSE 1588.188175 1836.402 1647.267501 1703.422404 1576.079474 1555.138343 1537.151288 2216.495321 1596.134325 1918.633312 0.827770562 0.957140684 0.858562963 0.887831142 0.821459455 0.810544846 0.801169915 1.15524697 0.83191213 1 10.9058633 -9.481059451 1.165451926 1.001441331 0.877411764 0 0.11239932 0.680417497 1.622247977 0.06931848 0.016169075 3.30E-10 9.481059451 -0.124029567 RT(ph)ASPPPPPKR ddPTM_HeLa_Curcumin_4h_R1 1 RTASPPPPPKR 11 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 RT(0.655)AS(0.345)PPPPPKR 82.749 0.010866 5145100 2124.1 1877.3 1853.8 1600.2 1615.9 2322.8 1820.5 2742.3 2478.4 1873.5 TRUE FALSE FALSE 1955.975244 2039.565447 1922.503459 1593.578796 1596.631448 1841.025097 1871.57833 3578.414646 2206.525721 1938.603986 1.008960705 1.052079467 0.991694783 0.822023894 0.823598558 0.949665383 0.965425814 1.845871912 1.138203438 1 10.92080241 -4.260980185 24.97226437 0.976896966 1.845872179 0.893512422 0.090450106 7.792740598 423657.1366 0.011633575 0.091992708 5.48E-05 4.260980185 0.868975213 RT(ph)GSNISGASSDISLDEQYK ddPTM_HeLa_Curcumin_4h_R1 1 RTGSNISGASSDISLDEQYK 20 1 P22059 P22059 OSBP Oxysterol-binding protein 1 1 0 RT(0.475)GS(0.475)NIS(0.05)GAS(0.001)SDISLDEQYK 119.48 0.00019363 0 3399.8 2754.7 3407.2 3360.7 3494.4 3112.4 1894.4 1497.1 3346.5 3343.8 TRUE FALSE FALSE 3130.702243 2992.803993 3533.473829 3346.794314 3452.731562 2466.853156 1947.551765 1953.558898 2979.397323 3459.996801 0.904828074 0.864973052 1.021236155 0.967282488 0.997900218 0.712963999 0.562876753 0.56461292 0.861098288 1 11.75655499 -5.063145375 2.989958713 0.955681409 0.566595035 0.891144729 0.054542801 0.054270822 0.947451968 0.007697058 0.024032742 8.65E-06 5.063145375 -0.389086374 RT(ph)PSDDEEDNLFAPPK ddPTM_HeLa_Curcumin_4h_R1 1 RTPSDDEEDNLFAPPK 16 1 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q641Q2;F8W7U3;E7ESD2;Q641Q2-2 A0A0A0MR88;Q641Q2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 0 RT(0.588)PS(0.412)DDEEDNLFAPPK 77.08 0.0081163 334570000 5658.4 5183.7 5354.1 6045.5 6278.1 6455.6 5251.7 4821.5 5848.9 5096.4 TRUE FALSE FALSE 5210.531669 5631.75593 5552.527656 6020.485323 6203.237758 5116.63579 5399.048568 6291.553155 5207.290303 5273.499521 0.98805957 1.067935231 1.05291138 1.141648975 1.176303844 0.970254339 1.023807539 1.193050863 0.987444918 1 12.36454494 -7.07668213 2.133927718 0.993953812 1.091003922 0.331883527 0.064055229 0.278893816 2.476579055 0.011230754 0.014261333 8.38E-08 7.07668213 0.09705011 RT(ph)PSLALTPPQAEQEVDVLDVNVR ddPTM_HeLa_Curcumin_4h_R1 1 RTPSLALTPPQAEQEVDVLDVNVR 24 1 Q04721 Q04721 NOTCH2 Neurogenic locus notch homolog protein 2;Notch 2 extracellular truncation;Notch 2 intracellular domain 1 0 RT(0.694)PS(0.166)LALT(0.139)PPQAEQEVDVLDVNVR 62.57 0.0021226 1945900 482.87 398.46 393.57 519.16 485.69 719.48 394.86 532.91 759.09 483.98 TRUE FALSE FALSE 444.65033 432.9011069 408.1560504 517.0118535 479.898464 570.2517378 405.9387089 695.3918058 675.8197261 500.798269 0.887883121 0.864422131 0.815010905 1.03237548 0.958267018 1.138685521 0.810583291 1.388566712 1.349484948 1 8.968085765 -4.250560118 24.75806409 0.944144838 1.388567004 0.34060075 0.160401351 651.6232181 1482874.736 0.013141639 0.257649547 5.62E-05 4.250560118 0.444422166 RT(ph)PTMPQEEAAEK ddPTM_HeLa_Curcumin_4h_R1 3 RTPTMPQEEAAEK 13 1 Q9NYV4-2 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 0 RT(0.971)PT(0.029)MPQEEAAEK;RT(0.985)PT(0.015)MPQEEAAEK;RT(0.991)PT(0.009)MPQEEAAEK ;; 137.39 0.011564 63004000 9978.7 9486.4 10399.9 9710.6 10659.6 11405.8 9537.8 9268.5 9848 8324 TRUE FALSE FALSE 9188.875366 10306.36215 10785.32944 9670.42011 10532.49123 9040.10851 9805.404998 12094.42298 8767.699038 8613.25838 1.066829179 1.196569485 1.252177627 1.122736563 1.22282309 1.049557335 1.13840832 1.404163494 1.017930573 1 13.07234339 -7.416544305 2.469625444 1.026139911 1.190677978 0.435115754 0.089009835 0.202651053 2.349492369 0.015992655 0.017938104 3.83E-08 7.416544305 0.164538067 RT(ph)RS(ph)VT(ph)SPRK ddPTM_HeLa_Curcumin_4h_R1 1 RTRSVTSPRK 10 3 O60673-2;O60673 O60673-2 REV3L DNA polymerase zeta catalytic subunit 3 0 RT(0.975)RS(0.975)VT(0.975)S(0.076)PRK 45.68 0.0095094 0 1677.7 1556.1 1637.2 1667.1 1780.2 1735.2 1348.5 1451.3 1707.4 1580.6 TRUE FALSE FALSE 1544.908275 1690.60235 1697.876072 1660.201982 1758.972278 1375.29996 1386.335281 1893.794689 1520.102492 1635.525732 0.944594294 1.033675177 1.038122506 1.015087656 1.075478204 0.840891667 0.847638929 1.157911888 0.929427438 1 10.67553874 -4.229672408 24.0064056 0.975977251 1.157912448 0.356280156 0.075543933 7571.56443 5721695.441 0.010400512 1.921184526 5.89E-05 4.229672408 0.181935197 RT(ph)S(ph)DACSSPLATSRSARSCGVLTAPVK ddPTM_HeLa_Curcumin_4h_R1 1 RTSDACSSPLATSRSARSCGVLTAPVK 27 3 F6UBL3 F6UBL3 CELF6 2 0 RT(0.78)S(0.7)DACS(0.229)S(0.217)PLAT(0.018)S(0.018)RS(0.037)ARSCGVLTAPVK 48.641 0.0068288 0 814.85 691.51 812.46 876.12 965.83 744.76 570.38 435.73 615.77 595.42 TRUE FALSE FALSE 750.3537627 751.2810431 842.5704823 872.4948476 954.3131081 590.2883808 586.3833277 568.5820711 548.2215716 616.1108007 1.217887695 1.219392749 1.367563239 1.416133018 1.548930983 0.958088026 0.951749794 0.922856847 0.889810033 1 9.267046017 -5.0458041 24.99418582 1.186817544 0.941706255 0.322348179 0.184926381 445.6665654 243189.1146 0.028178836 0.07184541 9.00E-06 5.0458041 -0.245111289 RT(ph)SEMDLINKEAQK ddPTM_HeLa_Curcumin_4h_R1 1 RTSEMDLINKEAQK 14 2 Q8TD26 Q8TD26 CHD6 Chromodomain-helicase-DNA-binding protein 6 1 0 RT(0.771)S(0.229)EMDLINKEAQK 66.965 0.017648 22432000 2039.6 2445.7 1712.2 2533.1 2729.3 309.11 718.85 807.95 2209.4 2648.7 TRUE FALSE FALSE 1878.163508 2657.09541 1775.655638 2522.618703 2696.75488 244.9971016 739.0189963 1054.290236 1967.034348 2740.742128 0.685275528 0.969480267 0.647874027 0.920414466 0.983950607 0.089390789 0.26964193 0.38467327 0.717701358 1 11.42035088 -5.263240649 24.99771667 0.854574742 0.250075975 0.798350899 0.137791724 54.52730314 756727.4555 0.021596459 0.050738496 5.45E-06 5.263240649 -0.604498767 RT(ph)SFSFQK ddPTM_HeLa_Curcumin_4h_R1 1 RTSFSFQK 8 1 H0Y7F8;Q9BPZ7-4;Q9BPZ7-3;Q9BPZ7-2;Q9BPZ7 H0Y7F8 MAPKAP1 Target of rapamycin complex 2 subunit MAPKAP1 1 0 RT(0.994)S(0.006)FSFQK 101.3 0.0074828 88233000 3936.5 2780.3 3270.9 3485 3460.6 4349.8 3796.3 2375.7 3685.7 3178.8 TRUE FALSE FALSE 3624.921871 3020.616743 3392.122431 3470.579993 3419.334605 3447.602448 3902.813961 3100.039994 3281.387931 3289.263063 1.102046812 0.918326289 1.03127125 1.055123876 1.039544281 1.048138255 1.186531416 0.942472503 0.997605807 1 11.68354868 -4.981082337 24.99858914 1.038185979 1.077710134 0.014503617 0.072123027 629.4620626 831787.4006 0.009784811 0.029349069 1.04E-05 4.981082337 0.039524156 RT(ph)SFYLPK ddPTM_HeLa_Curcumin_4h_R1 1 RTSFYLPK 8 1 Q9NS23-3;Q9NS23-4;Q9NS23-2;Q9NS23-5;Q9NS23 Q9NS23-3 RASSF1 Ras association domain-containing protein 1 1 0 RT(0.637)S(0.363)FYLPK 77.379 0.018293 36412000 2357.2 2359.2 2268.2 2703.6 1912.1 2955.6 2199.7 1273.9 2520.7 2144.8 TRUE FALSE FALSE 2170.625133 2563.118736 2352.261487 2692.41322 1889.299456 2342.575244 2261.417662 1662.306246 2244.185516 2219.33164 0.978053524 1.154905688 1.059896342 1.213163986 0.851292084 1.055531855 1.018963376 0.749012097 1.011198811 1 11.11590955 -4.261122342 23.30697559 1.016683562 0.74901191 0.440625228 0.094998258 7.454170557 547292.3356 0.012761334 0.099781574 5.48E-05 4.261122342 -0.267671652 RT(ph)SIETNIR ddPTM_HeLa_Curcumin_4h_R1 1 RTSIETNIR 9 1 P14859-6;P14859-2;P14859;P14859-3;P14859-5;P14859-4;A0A0C4DG88;A0A0A0MT46;Q9UKI9;Q9UKI9-2;H0YLC5;Q9UKI9-3 P14859-6 POU2F1;POU2F3 "POU domain, class 2, transcription factor 1;POU domain protein;POU domain, class 2, transcription factor 3" 1 0 RT(0.867)S(0.132)IET(0.001)NIR 77.387 0.018775 5765400 1032 883.21 972.58 1116.7 1111.6 1137.8 1105.3 1163.5 1087.3 915.11 TRUE FALSE FALSE 950.316111 959.5507369 1008.62467 1112.079391 1098.344896 901.8074544 1136.311743 1518.245794 968.0259103 946.9100044 1.003597075 1.013349455 1.065174796 1.174429868 1.159925327 0.952368705 1.200020845 1.603368627 1.022299802 1 9.887083506 -4.317890139 2.541467304 1.028046777 1.6888024 0.846791488 0.070518117 0.122808878 1.084734273 0.010839203 0.16391495 4.81E-05 4.317890139 0.660755623 RT(ph)SPQVLGSILK ddPTM_HeLa_Curcumin_4h_R1 2 RTSPQVLGSILK 12 1 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 RT(0.499)S(0.499)PQVLGS(0.001)ILK;RT(0.875)S(0.125)PQVLGSILK ; 109.48 0.0030021 277590000 29334.1 20858.8 25423.4 23429.3 24002.5 25499.1 17016.6 16241.9 26869.5 23716.2 TRUE FALSE FALSE 27012.27503 22661.74173 26365.61357 23332.35576 23716.28586 20210.29923 17494.04 21193.98054 23921.98307 24540.33618 1.100729624 0.923448707 1.074378663 0.950775718 0.966420577 0.823554293 0.7128688 0.863638557 0.974802582 1 14.58286739 -5.441835353 1.36599106 1.038584242 0.777002786 0.655802728 0.064471505 0.169541084 0.601132373 0.009817617 0.033095092 3.62E-06 5.441835353 -0.261581456 RT(ph)SSEDNLYLAVLR ddPTM_HeLa_Curcumin_4h_R1 1 RTSSEDNLYLAVLR 14 1 Q15149-4 Q15149-4 PLEC Plectin 1 0 RT(0.481)S(0.281)S(0.238)EDNLYLAVLR 109.36 0.0016064 8143800 1206.3 931.69 1014.8 1008.7 852.16 1027.1 618.6 1074.6 1136 1133.1 TRUE FALSE FALSE 1110.820082 1012.221132 1052.409381 1004.526267 841.9985486 814.0678822 635.9562511 1402.240593 1011.383642 1172.475141 0.947414613 0.863319909 0.897596328 0.856756985 0.718137655 0.694315687 0.542404891 1.195966161 0.862605617 1 10.19534162 -6.774945776 0.869871952 0.982216484 0.771232499 0.085104009 0.162873244 0.563381474 0.852697054 0.030863206 0.049074024 1.68E-07 6.774945776 -0.210983984 RT(ph)SSEELR ddPTM_HeLa_Curcumin_4h_R1 1 RTSSEELR 8 1 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 0 RT(0.96)S(0.039)S(0.001)EELR 87.696 0.012401 2566200 522.52 1086.5 776.52 670.62 496.44 1005.7 720.27 1036.5 704.13 785.23 TRUE FALSE FALSE 481.1619906 1180.412219 805.2985143 667.8451521 490.5202772 797.1064834 740.4788377 1352.524079 626.8887006 812.5166841 0.592187213 1.452785207 0.991116281 0.821946386 0.603704868 0.981033989 0.911339856 1.664610838 0.771539481 1 9.666253627 -4.241493978 3.553995922 0.860150014 1.777721219 0.480064594 0.23452711 0.226359989 4.82622837 0.035477322 0.564914175 5.73E-05 4.241493978 0.917571205 RT(ph)SSTLDSEGTFNSYR ddPTM_HeLa_Curcumin_4h_R1 1 RTSSTLDSEGTFNSYR 16 1 Q92609;Q92609-2;C9JNM0;C9JED7;F2Z3C3;C9K0P2;C9J397;C9JWX0;C9JW04;C9JDR8 Q92609 TBC1D5 TBC1 domain family member 5 1 0 RT(0.958)S(0.03)S(0.009)T(0.003)LDSEGTFNSYR 90.498 0.0028408 8135100 1122.1 1590.4 1462.3 1168.9 1195.1 1363 1305.4 1052.5 1417.2 1766.9 TRUE FALSE FALSE 1033.284601 1727.867089 1516.494124 1164.063402 1180.849213 1080.298436 1342.026011 1373.402405 1261.736706 1828.299643 0.565161518 0.945067782 0.829456008 0.636691806 0.645872911 0.59087603 0.734029575 0.751191092 0.690114834 1 10.83628682 -6.263702321 24.258512 0.805489694 0.669264597 0.233666134 0.121498585 216.6390761 2322355.621 0.026024908 0.040970128 5.45E-07 6.263702321 -0.136225096 RT(ph)STPVIMEGVQEETDTR ddPTM_HeLa_Curcumin_4h_R1 2 RTSTPVIMEGVQEETDTR 18 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 RT(0.333)S(0.333)T(0.333)PVIMEGVQEETDTR;RT(0.353)S(0.353)T(0.293)PVIMEGVQEETDTR ; 173.77 2.51E-06 13914700 1907.61 1436.8 1742.44 1998.4 1478.77 1884.31 1396.56 1378.256 1942.17 1877.87 TRUE FALSE FALSE 1756.620656 1560.99059 1807.016359 1990.13115 1461.136634 1493.482865 1435.743715 1798.47991 1729.11881 1943.125843 0.904017958 0.803339936 0.929953336 1.024190563 0.751951624 0.768598118 0.738883547 0.925560183 0.889864553 1 10.92416362 -7.809210348 0.168574245 1.085326787 0.742650255 0.130258971 0.090720625 3.59531151 0.472240869 0.483867211 0.362211977 1.55E-08 7.809210348 -0.342676532 RT(ph)SVPSPEQPQPYR ddPTM_HeLa_Curcumin_4h_R1 1 RTSVPSPEQPQPYR 14 1 Q8TEH3 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 0 RT(0.606)S(0.172)VPS(0.222)PEQPQPYR 86.005 0.00713 14571000 1420.5 1413 1280.6 1347.6 1477.2 1456.7 1073.2 963.83 1553.4 1631.2 TRUE FALSE FALSE 1308.065926 1535.133424 1328.060163 1342.023988 1459.585355 1154.564 1103.311104 1257.69733 1382.995906 1687.884079 0.774973793 0.909501691 0.786819533 0.79509251 0.864742652 0.684030387 0.653665212 0.745132528 0.81936664 1 10.72100011 -13.52287875 0.117036485 1.765781729 0.639480738 0.326959282 0.080022205 42.31199946 0.359498665 7.73792191 0.336976709 3.00E-14 13.52287875 -1.126300991 GLDIESYDS(ph)LERPLRK ddPTM_HeLa_Curcumin_4h_R1 2 GLDIESYDSLERPLRK 16 2 Q9H792 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 0 GLDIES(0.034)YDS(0.966)LERPLRK;GLDIES(0.053)Y(0.007)DS(0.94)LERPLRK ; 61.167 0.01145 56472000 15168.1 13182.3 13777.7 13811.7 13427.3 17957.1 13507.4 2660.5 16805.3 14360.1 TRUE FALSE FALSE 13967.52888 14321.71927 14288.31368 13754.55085 13267.18822 14232.59504 13886.38129 3471.674203 14961.80063 14859.11241 0.939997525 0.963834103 0.961585948 0.925664365 0.892865459 0.957836151 0.934536392 0.233639406 1.006910792 1 13.85906032 -4.261080405 5.491573064 0.959773816 0.206869671 0.979245705 0.031458255 0.015589247 1.79580869 0.004856733 0.043891365 5.48E-05 4.261080405 -0.752904145 down KTGS(ph)YGALAEITASK ddPTM_HeLa_Curcumin_4h_R1 1 KTGSYGALAEITASK 15 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 KT(0.093)GS(0.907)YGALAEITASK 104.82 0.0013014 660110000 7109.7 5712.5 5791.3 7274.7 6079.6 9087.6 5529.3 1466.6 7618.5 7478 TRUE FALSE FALSE 6546.959743 6206.263046 6005.930673 7244.599219 6007.104741 7202.729322 5684.437277 1913.759589 6782.769611 7737.859943 0.846094371 0.802064536 0.776174642 0.936253599 0.776326372 0.930842555 0.73462654 0.247324144 0.876569188 1 12.9177189 -4.260886012 2.301397397 0.89656797 0.084325855 0.859436299 0.074417777 0.179431645 1.099589157 0.012778244 0.29278422 5.48E-05 4.260886012 -0.812242115 down RTAFYNEDDS(ph)EEEQR ddPTM_HeLa_Curcumin_4h_R1 2 RTAFYNEDDSEEEQR 15 1 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 0 RTAFYNEDDS(1)EEEQR;RTAFYNEDDS(1)EEEQR ; 139.39 3.48E-05 9971000 2321.33 1726.54 1870.67 2613.96 2040.78 2245.92 2082.92 1618.8 2067.8 1841.53 TRUE FALSE FALSE 2137.594281 1875.774424 1939.998676 2603.144126 2016.445031 1780.090875 2141.361129 2112.364668 1840.967513 1905.52303 1.121788741 0.98438822 1.018092484 1.366104783 1.05821079 0.934174422 1.123765546 1.108548485 0.966121891 1 10.89597133 -9.480357948 0.976116068 0.994523984 1.09121622 0.124239177 0.110333041 1.385037596 2.130724008 0.102155749 0.019869578 3.31E-10 9.480357948 0.096692235 RTAQEVETYR ddPTM_HeLa_Curcumin_4h_R1 1 RTAQEVETYR 10 1 P17844-2;P17844;J3KTA4;J3QRQ7;J3QR02;J3KRX8;J3KTQ4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 0 91.701 0.0055085 1980200 216.12 198.07 321.52 57.386 259.65 250.68 226.02 189.29 278.13 228.35 FALSE FALSE TRUE 199.013874 215.1902882 333.435814 57.14855194 256.5538433 198.6861423 232.3615129 247.0036496 247.6198348 236.2851455 0.84226147 0.91072288 1.411158595 0.241862652 1.085780669 0.840874452 0.983394502 1.045362581 1.047970385 1 7.884385124 -9.648584791 1.490898084 0.999893475 0.906957032 0.018243139 0.276567137 1.973103486 7.901916148 0.179872292 0.040874923 2.25E-10 9.648584791 -0.092936443 RTAS(ph)NPKVENEDEPVR ddPTM_HeLa_Curcumin_4h_R1 1 RTASNPKVENEDEPVR 16 2 Q9UBF8-2 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 0 RT(0.14)AS(0.86)NPKVENEDEPVR 86.498 0.005898 7159000 1362.1 932.98 1015.2 983.07 1168.9 1202.1 876.84 1019.8 1370.7 1258.2 TRUE FALSE FALSE 1254.288348 1013.622634 1052.824205 979.0023168 1154.961631 952.7709095 901.4417705 1330.732325 1220.337639 1301.922356 0.963412558 0.778558436 0.808668965 0.751966745 0.887120208 0.731818533 0.692392881 1.022128792 0.93733519 1 10.3464277 -7.317742731 5.026622818 0.983798599 0.803394578 0.391734352 0.088473595 0.124483015 6.747892253 0.013927147 0.015976818 4.81E-08 7.317742731 -0.180404022 RTAS(ph)PPPPPKR ddPTM_HeLa_Curcumin_4h_R1 1 RTASPPPPPKR 11 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 RT(0.285)AS(0.715)PPPPPKR 61.48 0.014872 13485000 1480.9 1083.7 1321.2 1496.2 1214.2 1785.3 1228.1 1912.8 1650.1 1339.1 TRUE FALSE FALSE 1363.685202 1177.370199 1370.164834 1490.009121 1199.721458 1415.008656 1262.557181 2496.003915 1469.088158 1385.633625 0.98416001 0.849698057 0.988836305 1.075326907 0.86582877 1.021199709 0.911176777 1.801344792 1.060228427 1 10.43633013 -4.258633785 24.9912102 0.97753282 1.801345089 0.9220364 0.072255228 43.01858582 383172.7685 0.008646074 0.080246907 5.51E-05 4.258633785 0.823812269 LDDGHLNNSLSS(ph)PVQADVYFPR ddPTM_HeLa_Curcumin_4h_R1 1 LDDGHLNNSLSSPVQADVYFPR 22 0 F8WF17;B9A055;U3KQ88;Q3ZCW2 F8WF17 LGALSL Galectin;Galectin-related protein 1 0 LDDGHLNNS(0.002)LS(0.259)S(0.739)PVQADVYFPR 122.59 4.60E-06 11713000 1643.6 1603.3 1528.8 1470.3 1601.9 2332.1 2002.3 4366.6 1920.4 1423.6 TRUE FALSE FALSE 1513.507326 1741.882108 1585.458673 1464.216288 1582.798389 1848.396172 2058.479149 5697.956239 1709.736925 1473.069994 1.027451059 1.182484278 1.076295546 0.993989623 1.0744896 1.254791815 1.397407562 3.868082482 1.16066238 1 10.52461027 -4.1993406 2.499611323 1.045225978 4.7783699 0.986758559 0.095525742 0.05054911 0.337275605 0.013548857 0.425664539 6.32E-05 4.1993406 3.733143922 up ADGAPSAAPPDGLLAS(ph)PDLGLLK ddPTM_HeLa_Curcumin_4h_R1 1 ADGAPSAAPPDGLLASPDLGLLK 23 0 P17535 P17535 JUND Transcription factor jun-D 1 0 ADGAPSAAPPDGLLAS(1)PDLGLLK 115.34 2.07E-06 1867500 1224.3 1279 1088.6 1212.4 1208.8 1717.8 1657.7 4365.2 1202.8 829.69 TRUE FALSE FALSE 1127.395363 1389.551061 1128.944474 1207.38341 1194.385849 1361.508916 1704.210601 5696.129385 1070.855849 858.5216657 1.313182192 1.618539306 1.314986585 1.406351707 1.39121224 1.585876013 1.985052525 6.634811458 1.247325364 1 9.745710732 -4.199085762 2.44133877 1.253749144 8.418848819 0.984719756 0.195465266 0.070265828 0.439552221 0.034874561 1.117578925 6.32E-05 4.199085762 7.165099675 up RTDEAAFQK ddPTM_HeLa_Curcumin_4h_R1 1 RTDEAAFQK 9 1 P26447 P26447 S100A4 Protein S100-A4 0 0 117.71 0.00043809 3664700 1160.5 2221.9 1398.4 1746.6 967.06 801.42 1013.4 782.14 1533 2072.4 FALSE FALSE TRUE 1068.6452 2413.951135 1450.225934 1739.373032 955.5284411 635.1964581 1041.833277 1020.610885 1364.833735 2144.415746 0.498338628 1.12569176 0.676280212 0.81111745 0.445589174 0.296209566 0.485835491 0.475938907 0.636459482 1 11.06636892 -5.741938045 7.386892367 0.78368172 0.419482727 0.514108429 0.173927069 0.130859498 31.08691305 0.031179414 0.061213808 1.81E-06 5.741938045 -0.364198993 RTDPECTAPIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 RTDPECTAPIKK 12 2 Q5T7F5;Q8N1G2 Q5T7F5 CMTR1 Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 0 1 ; RTDPECTAPIK(1)K;RTDPECTAPIK(1)K 124.07 0.0001802 25576000 9684.8 9495.8 10648.7 9546.2 7542.2 9968.1 6987.7 5989.3 8116 9301 FALSE TRUE FALSE 8918.237861 10316.57464 11043.35019 9506.700354 7452.264191 7900.603696 7183.756056 7815.409999 7225.695105 9624.209058 0.926646315 1.071939998 1.147455352 0.9877903 0.774324845 0.820909401 0.746425604 0.812057381 0.750783266 1 13.23245227 -5.764139587 24.93223536 0.99001222 0.787749029 0.477919569 0.098198405 32.48032849 299910.0035 0.010824264 0.020282236 1.72E-06 5.764139587 -0.202263191 RTDYVS(ph)PTASALR ddPTM_HeLa_Curcumin_4h_R1 1 RTDYVSPTASALR 13 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 RT(0.012)DYVS(0.98)PT(0.007)AS(0.001)ALR 92.952 0.016786 3584600 1611.4 1474 1332.4 1563.4 1611.3 2336.4 1386.7 1079.9 1621.7 1265.5 TRUE FALSE FALSE 1483.85599 1601.405992 1381.779916 1556.931065 1592.0863 1851.804303 1425.60707 1409.156539 1443.803567 1309.476031 1.133167736 1.222936468 1.055215891 1.188972557 1.215819352 1.414156701 1.08868512 1.076122438 1.102581134 1 10.35477394 -8.529597561 0.458698439 0.983782252 1.195394294 0.17443867 0.101252212 1.041665735 0.438872546 0.097673315 0.034016806 2.95E-09 8.529597561 0.211612042 RTEARS(ph)S(ph)DEENGPPS(ph)SPDLDR ddPTM_HeLa_Curcumin_4h_R1 1 RTEARSSDEENGPPSSPDLDR 21 2 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 3 0 RT(0.13)EARS(0.933)S(0.924)DEENGPPS(0.616)S(0.396)PDLDR 66.437 0.0032678 30957000 1464.8 1586.2 1375 1430.4 1301 1527.8 1008.4 898.5 1655.1 1216.3 TRUE FALSE FALSE 1348.859534 1723.30406 1425.95871 1424.481384 1285.486425 1210.917058 1036.69299 1172.448514 1473.539671 1258.566334 1.071742901 1.369259619 1.133002425 1.131828609 1.021389489 0.962140036 0.823709455 0.931574667 1.17080811 1 10.29756554 -5.181840006 2.333137771 1.076491121 0.879432266 0.440043776 0.107275406 0.277578045 2.911981437 0.017126077 0.053583997 6.58E-06 5.181840006 -0.197058855 RTEARSS(ph)DEENGPPS(ph)SPDLDR ddPTM_HeLa_Curcumin_4h_R1 1 RTEARSSDEENGPPSSPDLDR 21 2 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 2 0 RT(0.018)EARS(0.248)S(0.735)DEENGPPS(0.539)S(0.46)PDLDR 64.422 0.0046337 8445900 1188.1 885.37 943.06 967.67 693.33 1137 890.49 904.33 1213.5 942.44 TRUE FALSE FALSE 1094.060631 961.8974377 978.0106332 963.6660379 685.0624926 901.1733834 915.4747528 1180.056054 1080.382086 975.1897199 1.121895165 0.986369542 1.002892682 0.988183138 0.702491504 0.924100578 0.938765795 1.210078439 1.107868617 1 9.929539107 -6.654445854 1.869423664 1.055942902 0.939252705 0.140837053 0.120481368 0.483419849 3.440901927 0.020707339 0.031143991 2.22E-07 6.654445854 -0.116690197 RTEEPDRDER ddPTM_HeLa_Curcumin_4h_R1 2 RTEEPDRDER 10 2 O95232;J3KPP4;H0YA81 O95232 LUC7L3 Luc7-like protein 3 0 0 ; ; 74.173 0.015035 5237400 787.33 1029.35 747.68 844.74 594.78 1010.78 553.737 670.44 800.44 767.67 FALSE FALSE TRUE 725.0119997 1118.322427 775.3896785 841.2446897 587.687637 801.1328342 569.2733699 874.8540697 712.6337346 794.3464754 0.912715071 1.407852193 0.976135355 1.059039998 0.739837911 1.008543323 0.716656255 1.101350729 0.897132116 1 9.633624604 -5.798886196 24.99959995 1.002957112 0.887453959 0.131276311 0.172781065 303.4047512 202553.0561 0.024615189 0.044619583 1.59E-06 5.798886196 -0.115503153 RTES(ph)VPSDINNPVDR ddPTM_HeLa_Curcumin_4h_R1 5 RTESVPSDINNPVDR 15 1 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 0 RT(0.012)ES(0.988)VPSDINNPVDR;RT(0.029)ES(0.97)VPSDINNPVDR;RT(0.034)ES(0.966)VPSDINNPVDR;RT(0.025)ES(0.974)VPSDINNPVDR;RT(0.002)ES(0.997)VPS(0.001)DINNPVDR ;;;; 128.4 0.00035263 263877000 5288.34 4646.96 4844.02 4958.44 5175.15 6462.02 4724.71 3759.63 5635.31 5675.11 TRUE FALSE FALSE 4869.762309 5048.622516 5023.543642 4937.923289 5113.439716 5121.72421 4857.272647 4905.92388 5017.130592 5872.31965 0.829274052 0.859732238 0.855461545 0.840881216 0.870769989 0.872180759 0.827147181 0.835432022 0.854369464 1 12.51971479 -9.288977506 0.80021173 1.009933616 0.848227195 0.020199291 0.047165542 0.15315359 0.158685293 0.016069692 0.003425725 5.14E-10 9.288977506 -0.161706421 RTFS(ph)LTEVR ddPTM_HeLa_Curcumin_4h_R1 1 RTFSLTEVR 9 1 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 0 RT(0.018)FS(0.93)LT(0.051)EVR 117.02 0.011036 9902500 1571.3 1547.2 1663.7 1479.1 1405.7 1470.2 1290.5 1960.5 1677.6 1560.6 TRUE FALSE FALSE 1446.929947 1680.933074 1725.358186 1472.979876 1388.937946 1165.263947 1326.707957 2558.247425 1493.571477 1614.830734 0.896025767 1.040934532 1.068445224 0.912157445 0.860113643 0.721601294 0.821577103 1.584220173 0.924908999 1 10.65716723 -4.255383768 24.90163662 0.933436726 1.584220475 0.801344769 0.099449476 235.3974232 967962.4829 0.015142828 0.184969034 5.55E-05 4.255383768 0.650783749 RTHT(ph)GEKPY(ph)VCT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 RTHTGEKPYVCTK 13 2 G3V1M0;Q9Y5A6 G3V1M0 ZSCAN21 Zinc finger and SCAN domain-containing protein 21 3 0 RT(0.004)HT(0.996)GEKPY(1)VCT(1)K 70.908 0.010158 6563500 588.76 485.7 683.87 667.67 597.65 1053.7 867.93 648.59 685.59 563.84 TRUE FALSE FALSE 542.1590247 527.6817438 709.2148238 664.9073584 590.5234141 835.1507424 892.2817799 846.3421053 610.3824923 583.433398 0.929256067 0.904442127 1.215588319 1.139645692 1.012152229 1.431441438 1.529363562 1.450623341 1.046190524 1 9.188424164 -5.25480819 0.7969364 0.969427894 1.585503781 0.767945025 0.105175859 0.296272043 0.280153969 0.017790885 0.120057685 5.56E-06 5.25480819 0.616075887 RTIQEVLEEQS(ph)EDEDR ddPTM_HeLa_Curcumin_4h_R1 2 RTIQEVLEEQSEDEDR 16 1 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 RTIQEVLEEQS(1)EDEDR;RTIQEVLEEQS(1)EDEDR ; 172.99 3.68E-05 12229300 3888.7 3269.8 4355.1 4363.6 4581.4 5063 4061.6 3711.2 4302 3897.9 TRUE FALSE FALSE 3580.905292 3552.426942 4516.503837 4345.544579 4526.769797 4012.876728 4175.557565 4842.727796 3830.081363 4033.351735 0.887823708 0.880762992 1.119789231 1.077402831 1.122334499 0.994923575 1.035257483 1.200670835 0.949602617 1 11.97776351 -6.755252864 24.99179926 0.940577891 1.085502453 0.630563162 0.060468108 89.51877949 361629.4552 0.010765207 0.015006747 1.76E-07 6.755252864 0.144924562 RTIQEVLEEQS(ph)EDEDREAK ddPTM_HeLa_Curcumin_4h_R1 2 RTIQEVLEEQSEDEDREAK 19 2 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 RTIQEVLEEQS(1)EDEDREAK;RTIQEVLEEQS(1)EDEDREAK ; 100.39 0.00070618 52087000 1898.34 1900.6 1858.32 1794.67 2079.61 2622.7 1682.69 1743.37 2241.1 1731.91 TRUE FALSE FALSE 1748.084386 2064.879395 1927.190974 1787.244131 2054.812009 2078.722456 1729.901753 2274.915488 1995.256937 1792.093744 0.975442491 1.152216173 1.075385136 0.997293885 1.146598506 1.159940691 0.965296463 1.269417683 1.113366387 1 10.80743039 -7.273642265 24.56441466 0.988403395 1.101652319 0.087373165 0.090670503 505.6804614 1017933.112 0.012709221 0.014590519 5.33E-08 7.273642265 0.113248924 RTIQLY(ph)EMY(ph)FK ddPTM_HeLa_Curcumin_4h_R1 1 RTIQLYEMYFK 11 1 Q9P2D1;Q9P2D1-2 Q9P2D1 CHD7 Chromodomain-helicase-DNA-binding protein 7 2 0 RTIQLY(1)EMY(1)FK 58.676 0.013458 11267000 3444.8 2720.3 3262.1 3346.3 3065.5 3586.2 3409.8 1691.3 3867.5 3001 TRUE FALSE FALSE 3172.140445 2955.430611 3382.996296 3332.453897 3028.945915 2842.381695 3505.469811 2206.969584 3443.244926 3105.284527 1.021529724 0.951742291 1.089431988 1.073155735 0.975416548 0.915336959 1.12887234 0.710714128 1.108833956 1 11.60050975 -4.247426483 24.95849286 1.013241435 0.710713919 0.654791359 0.06851668 978.0412967 1741968.992 0.007750802 0.216146586 5.66E-05 4.247426483 -0.302527516 RTLEGELHDLR ddPTM_HeLa_Curcumin_4h_R1 2 RTLEGELHDLR 11 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 105.25 0.0024535 33045100 8951 7227.5 7250.9 8415 7828.4 9988.4 6879 6119.4 9075.4 8902 FALSE FALSE TRUE 8242.518905 7852.212895 7519.624733 8380.18096 7735.051443 7916.693248 7072.006226 7985.17689 8079.851326 9211.343837 0.894822629 0.852450308 0.816343941 0.909767468 0.839731051 0.859450411 0.767749674 0.866885118 0.877163145 1 13.16919593 -8.616930711 0.333042765 1.038827598 0.823284431 0.208347329 0.051730889 0.745275225 0.159610712 0.062578812 0.019391722 2.42E-09 8.616930711 -0.215543167 RTLPSTSSSGSK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 RTLPSTSSSGSKR 13 2 A0A286YEX4;P08651-4;P08651-5;P08651-3;P08651-6;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 0 1 ; RTLPSTSSSGSK(1)R;RTLPSTSSSGSK(1)R 125.47 0.00030288 3082700 722.8 349.65 621.39 687.5 533.82 946.08 605.02 772.59 587.32 641.02 FALSE TRUE FALSE 665.5896173 379.872188 644.41926 684.6553072 527.4545451 749.8523435 621.9952329 1008.149134 522.8924654 663.2953973 1.003458821 0.572704393 0.971541884 1.032202711 0.795203083 1.130495322 0.937734885 1.519909739 0.788325183 1 9.373507705 -4.259736833 24.82942787 0.964734212 1.519909943 0.552170708 0.157827646 75.87851778 1106481.869 0.019754273 0.169276653 5.50E-05 4.259736833 0.555175731 RTPAPEPEPCEASELPAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 RTPAPEPEPCEASELPAKR 19 2 H0Y5D5;A0A494C0L7;Q9BTG3;Q5SYW2;F5H2X7;Q9ULV3-5;Q9ULV3-3;Q9ULV3-4;Q9ULV3-2;Q9ULV3 H0Y5D5 CIZ1 Cip1-interacting zinc finger protein 0 1 ; RTPAPEPEPCEASELPAK(1)R;RTPAPEPEPCEASELPAK(1)R 182.28 2.06E-08 5521500 1245.23 963.23 966.55 1077.39 737.15 1361.18 1051.81 901.87 1439.61 1119.43 FALSE TRUE FALSE 1146.668732 1046.487309 1002.371193 1072.932046 728.3599677 1078.855924 1081.320958 1176.846011 1281.688385 1158.330109 0.989932596 0.903444796 0.865358835 0.926274848 0.628801722 0.931389002 0.933517094 1.015984996 1.106496649 1 10.17783075 -7.202356677 3.07312485 0.996010583 0.878459141 0.286387366 0.100900962 0.279274158 5.174768778 0.016306898 0.019778868 6.28E-08 7.202356677 -0.117551441 RTPAPPEPGS(ph)PAPGEGPSGR ddPTM_HeLa_Curcumin_4h_R1 2 RTPAPPEPGSPAPGEGPSGR 20 1 P0C1Z6-2;P0C1Z6 P0C1Z6-2 TFPT TCF3 fusion partner 1 0 RTPAPPEPGS(0.999)PAPGEGPS(0.001)GR;RTPAPPEPGS(0.981)PAPGEGPS(0.018)GR ; 109.4 0.00012243 202759000 2947.12 2943.6 2224.58 2917.45 2843.2 3478.6 2797.2 2502.8 3155.4 2618.96 TRUE FALSE FALSE 2713.852342 3198.031668 2307.024892 2905.378365 2809.296697 2757.099148 2875.681904 3265.892199 2809.260514 2709.968665 1.001433108 1.180099131 0.851310542 1.072107734 1.036652834 1.017391523 1.061149504 1.205140207 1.036639482 1 11.40406045 RTPHVQAVQGPLGS(ph)PPKR ddPTM_HeLa_Curcumin_4h_R1 1 RTPHVQAVQGPLGSPPKR 18 2 Q15149 Q15149 PLEC Plectin 1 0 RTPHVQAVQGPLGS(1)PPKR 44.759 0.018466 59523000 1478.8 1453.4 1688.9 1299 1583 2020.4 1308.3 1028.7 1818.3 1470.4 TRUE FALSE FALSE 1361.75142 1579.02542 1751.49212 1293.625082 1564.123759 1601.346265 1345.007377 1342.345894 1618.837039 1521.496291 0.895008044 1.03781089 1.151164239 0.850232163 1.028016807 1.052481216 0.88400306 0.882253807 1.063976987 1 10.5712751 -4.673616922 13.55382984 0.973862414 0.882853991 0.169861531 0.08657149 1.153860368 173.8263639 0.011895435 0.044519915 2.12E-05 4.673616922 -0.091008423 RTPS(ph)DDEEDNLFAPPK ddPTM_HeLa_Curcumin_4h_R1 3 RTPSDDEEDNLFAPPK 16 1 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q641Q2;F8W7U3;E7ESD2;Q641Q2-2 A0A0A0MR88;Q641Q2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 0 RT(0.004)PS(0.996)DDEEDNLFAPPK;RT(0.001)PS(0.999)DDEEDNLFAPPK;RT(0.002)PS(0.998)DDEEDNLFAPPK ;; 148.97 0.00055884 228901000 9893.9 8687.5 8941.4 9247.3 9487.3 12085.3 9359.6 7798.58 10533.9 9312.7 TRUE FALSE FALSE 9110.787375 9438.408789 9272.77615 9209.037123 9374.170144 9578.672551 9622.205186 10176.33114 9378.357525 9636.315632 0.945463777 0.979462395 0.962274017 0.955659556 0.972796087 0.994018141 0.998535701 1.056039625 0.973230629 1 13.23426593 -3.917664049 1.080233505 0.971880373 1.15773392 0.759929218 0.01451756 1.724376806 0.973917119 0.003186227 0.436654087 0.000120875 3.917664049 0.185853547 RTQS(ph)SLTVSEVLTR ddPTM_HeLa_Curcumin_4h_R1 3 RTQSSLTVSEVLTR 14 1 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 RT(0.032)QS(0.915)S(0.052)LT(0.001)VSEVLTR;RTQS(0.95)S(0.025)LT(0.025)VSEVLTR;RT(0.003)QS(0.835)S(0.15)LT(0.012)VSEVLTR ;; 160.04 0.00047251 41837900 3647.1 2944.59 3548.67 3981.8 3226.97 4472.6 3441.03 1602.31 4294.71 4026.11 TRUE FALSE FALSE 3358.428187 3199.107239 3680.186832 3965.324367 3188.49049 3544.932343 3537.576041 2090.846943 3823.591058 4166.017023 0.806148455 0.767905465 0.883382572 0.951826252 0.765357048 0.850916433 0.849150645 0.501881517 0.917804953 1 12.02445302 -13.52287874 0.030391127 2.170031103 3.08E-13 0.370782886 0.103839865 917.6826355 2.239085374 122.0966163 51.82320744 3.00E-14 13.52287874 -2.170031103 RTS(ph)FSFQK ddPTM_HeLa_Curcumin_4h_R1 1 RTSFSFQK 8 1 H0Y7F8;Q9BPZ7-4;Q9BPZ7-3;Q9BPZ7-2;Q9BPZ7 H0Y7F8 MAPKAP1 Target of rapamycin complex 2 subunit MAPKAP1 1 0 RT(0.41)S(0.59)FSFQK 82.494 0.01373 93167000 5848.6 4431.2 5190.8 5729.3 5215.4 7239.1 5547.9 3790.8 6121.1 5465.2 TRUE FALSE FALSE 5385.677139 4814.213183 5383.175614 5705.593675 5153.209761 5737.629059 5703.559143 4946.597469 5449.630644 5655.115293 0.952354967 0.851302393 0.95191262 1.008926145 0.911247516 1.014590996 1.008566377 0.874712046 0.963663933 1 12.46534072 -8.885542961 1.08626797 0.99615523 0.950201779 0.047005348 0.05395076 0.792933903 1.848711412 0.022132295 0.00987583 1.30E-09 8.885542961 -0.045953451 RTS(ph)FSTSDVSK ddPTM_HeLa_Curcumin_4h_R1 1 RTSFSTSDVSK 11 1 M0R0P8;Q13459-2;Q13459;M0R300 M0R0P8 MYO9B Unconventional myosin-IXb 1 0 RT(0.009)S(0.988)FS(0.002)TS(0.001)DVSK 80.96 0.0091445 0 2431.8 1889.9 2507.5 2467.9 2022.1 3059.8 2605.5 2246.2 2778.1 2227.2 TRUE FALSE FALSE 2239.320464 2053.254535 2600.430156 2457.688484 1997.987778 2425.162989 2678.603318 2931.05604 2473.34938 2304.595034 0.971676338 0.890939408 1.128367508 1.066429653 0.866958294 1.05231633 1.162288071 1.271831275 1.073225163 1 11.17029755 -4.664515162 2.282524931 0.988478993 1.262904746 0.56519994 0.07695086 0.156309316 1.484478518 0.00992394 0.061163127 2.17E-05 4.664515162 0.274425753 RTS(ph)FYLPK ddPTM_HeLa_Curcumin_4h_R1 1 RTSFYLPK 8 1 Q9NS23-3;Q9NS23-4;Q9NS23-2;Q9NS23-5;Q9NS23 Q9NS23-3 RASSF1 Ras association domain-containing protein 1 1 0 RTS(1)FYLPK 110.38 0.017617 47848000 5684.5 5490.8 5554 5672.7 5447.1 6894.8 3878.3 2736.6 6676.9 5521.6 TRUE FALSE FALSE 5234.565827 5965.400285 5759.836126 5649.22787 5382.14689 5464.74076 3987.11466 3570.976742 5944.460775 5713.475189 0.916178972 1.044093146 1.008114315 0.988755124 0.942009322 0.9564653 0.697844049 0.625009582 1.040428212 1 12.48015281 -4.716134657 3.479691046 0.970612508 0.638090239 0.908473102 0.041366394 0.049631666 1.200606894 0.006073613 0.025793425 1.92E-05 4.716134657 -0.332522269 RTS(ph)MGGTQQQFVEGVR ddPTM_HeLa_Curcumin_4h_R1 1 RTSMGGTQQQFVEGVR 16 1 A0A2R8Y6G0;A0A2R8Y804;A0A2R8Y543;A0A2R8Y5C3;A0A2R8Y750;A0A2R8Y5Z1;B4DGU4;A0A2R8YCH5;A0A2R8Y5A3;P35222 A0A2R8Y6G0 CTNNB1 Catenin beta-1 1 0 RT(0.092)S(0.908)MGGTQQQFVEGVR 123.62 0.00024952 0 1710.9 1941.7 1759.8 2311.1 1824.5 3302.8 2138.3 1153.8 2022.6 1741.5 TRUE FALSE FALSE 1575.48046 2109.531896 1825.019736 2301.537281 1802.744029 2617.76205 2198.294943 1505.588309 1800.72584 1802.016995 0.874287237 1.170650389 1.012764997 1.277200652 1.000403456 1.45268444 1.219907997 0.835501725 0.999283495 1 10.8153969 -7.253763289 24.59026433 0.940635639 1.148857796 0.201764408 0.162610994 456.7852134 1463306.324 0.026133277 0.031682958 5.57E-08 7.253763289 0.208222156 RTS(ph)QEGPGDSVK ddPTM_HeLa_Curcumin_4h_R1 1 RTSQEGPGDSVK 12 1 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 0 RT(0.173)S(0.827)QEGPGDSVK 156 0.00015288 13476000 1890.8 2075.3 1830.5 1878.3 2024 2171.7 1714 1495.2 1834.7 1563.1 TRUE FALSE FALSE 1741.141185 2254.679685 1898.33994 1870.528092 1999.865122 1721.26494 1762.090227 1951.079597 1633.438 1617.417609 1.076494515 1.393999714 1.173685714 1.156490496 1.236455638 1.064205639 1.08944667 1.206293036 1.00990492 1 10.65947651 -7.495382487 14.43207255 1.033729477 1.184018115 0.430182834 0.085560978 1.91471732 1005.113643 0.015333973 0.016785563 3.20E-08 7.495382487 0.150288638 RTS(ph)SEDNLYLAVLR ddPTM_HeLa_Curcumin_4h_R1 2 RTSSEDNLYLAVLR 14 1 Q15149-4 Q15149-4 PLEC Plectin 1 0 RT(0.003)S(0.709)S(0.288)EDNLYLAVLR;RT(0.044)S(0.771)S(0.184)EDNLYLAVLR ; 182.91 4.20E-05 29524400 3325.4 2428.4 2932.7 2971.8 2822.1 3257.9 2331.9 1817.73 3262.2 3084.9 TRUE FALSE FALSE 3062.191081 2638.300075 3041.388442 2959.503479 2788.448301 2582.174816 2397.326838 2371.947509 2904.344822 3192.100045 0.959302978 0.826509206 0.952786065 0.927133685 0.87354665 0.808926656 0.751018704 0.743068035 0.909853946 1 11.64029015 -2.139723632 0.221092716 1.009182846 1.42E-11 0.679201504 0.04813038 8.65395684 0.161143646 0.031417701 2.834038871 0.007248971 2.139723632 -1.009182846 RTS(ph)SLDTITGPYLTGQWPR ddPTM_HeLa_Curcumin_4h_R1 1 RTSSLDTITGPYLTGQWPR 19 1 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 0 RT(0.017)S(0.49)S(0.49)LDT(0.002)ITGPYLTGQWPR 104.16 0.0011203 35948000 1849.5 1164.8 1201.3 1053.3 984.09 1527.7 1365.7 809.26 1519 1163.5 TRUE FALSE FALSE 1703.110123 1265.480122 1245.821235 1048.941724 972.3553695 1210.837799 1404.017866 1055.999649 1352.3695 1203.931538 1.41462373 1.051122993 1.034794085 0.871263598 0.807650052 1.005736423 1.166194108 0.877125995 1.123294355 1 10.23353764 -6.931829031 3.425183946 1.19696849 0.960708981 0.334481987 0.135255604 0.243223097 5.801722948 0.029809299 0.039453476 1.17E-07 6.931829031 -0.236259508 RTS(ph)TPVIMEGVQEETDTR ddPTM_HeLa_Curcumin_4h_R1 1 RTSTPVIMEGVQEETDTR 18 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 RT(0.093)S(0.453)T(0.453)PVIMEGVQEETDTR 99.414 0.00073487 6089300 1438.5 1128.6 1173.1 1264.1 901.17 1213.8 1013.8 570.5 1688.6 1264.5 TRUE FALSE FALSE 1324.641207 1226.151155 1216.576118 1258.869489 890.4241363 962.0441977 1042.244499 744.4428237 1503.364805 1308.441281 1.012381088 0.937108278 0.929790382 0.962113858 0.680522809 0.735259741 0.796554278 0.568953941 1.148973841 1 10.35363347 -5.821355656 0.92955368 1.004515671 0.670876798 0.764332761 0.081395767 0.176088029 0.290117742 0.010878701 0.034007249 1.51E-06 5.821355656 -0.333638873 RTSEEDTPK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 RTSEEDTPKK 10 2 A0A1B0GW41;Q8WYH8-2;Q8WYH8 A0A1B0GW41 ING5 Inhibitor of growth protein 5 0 1 ; RTSEEDTPK(1)K;RTSEEDTPK(1)K 138.76 5.80E-05 3083000 3953.1 4326.9 3661.5 3507.8 4043.9 3661.9 2039.33 1711.2 4114.1 3915.2 FALSE TRUE FALSE 3640.207964 4700.897956 3797.198411 3493.285653 3995.679134 2902.380662 2096.548111 2232.937003 3662.793523 4051.252909 0.898538809 1.160356577 0.937289894 0.862272915 0.986282324 0.71641557 0.517506105 0.551171959 0.904113766 1 11.98415244 -5.046597663 2.549678862 0.961785909 0.531132137 0.830819059 0.078907164 0.082084008 1.04224241 0.011483682 0.038927224 8.98E-06 5.046597663 -0.430653772 RTSS(ph)EDNLYLAVLR ddPTM_HeLa_Curcumin_4h_R1 2 RTSSEDNLYLAVLR 14 1 Q15149-4 Q15149-4 PLEC Plectin 1 0 RTS(0.038)S(0.961)EDNLYLAVLR;RTS(0.189)S(0.811)EDNLYLAVLR ; 205.98 1.81E-09 308190000 6379.3 5181.3 5180.4 5904 4674.5 6334.2 4135.9 3671.7 7154.2 5566.6 TRUE FALSE FALSE 5874.371674 5629.148485 5372.390181 5879.570812 4618.759641 5020.415519 4251.942223 4791.184428 6369.402159 5760.038936 1.019849299 0.977276117 0.932700324 1.020751922 0.801862573 0.871594025 0.738179424 0.831797229 1.105791511 1 12.49186285 -5.759371046 24.99981622 1.001238525 0.810005197 0.780929232 0.05140526 14.69273493 177585.7948 0.005662484 0.010893649 1.74E-06 5.759371046 -0.191233328 RTST(ph)PVIMEGVQEETDTR ddPTM_HeLa_Curcumin_4h_R1 1 RTSTPVIMEGVQEETDTR 18 1 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 RT(0.238)S(0.084)T(0.677)PVIMEGVQEETDTR 110.1 0.00039366 6924800 1206.1 1280.6 1079.3 1377.3 1030.4 1277.7 967.15 1267.5 1191.1 1302.7 TRUE FALSE FALSE 1110.635912 1391.289358 1119.299807 1371.601098 1018.113153 1012.690617 994.285626 1653.954915 1060.43931 1347.968728 0.823932996 1.032137711 0.830360367 1.017531838 0.755294342 0.751271596 0.737617725 1.226997986 0.786694296 1 10.39657131 -5.761893476 24.99999882 0.923612114 0.850173893 0.015342245 0.154032868 31.59859324 1739784.267 0.02132419 0.040444485 1.73E-06 5.761893476 -0.073438221 RTSVPS(ph)PEQPQPYR ddPTM_HeLa_Curcumin_4h_R1 1 RTSVPSPEQPQPYR 14 1 Q8TEH3 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 0 RT(0.002)S(0.029)VPS(0.968)PEQPQPYR 66.152 0.018176 3540900 1918.1 1791.3 1630.3 1813.4 1790.4 1756.2 1651.3 1089.2 2031.6 1725 TRUE FALSE FALSE 1766.280361 1946.13199 1690.720352 1805.896631 1769.050649 1391.944324 1697.631034 1421.292066 1808.738563 1784.943622 0.989544062 1.090304459 0.947212187 1.011738752 0.991096093 0.779825372 0.95108384 0.796267203 1.01333092 1 10.80166279 -5.329712681 8.466443855 0.999796068 0.853439749 0.652396842 0.05447367 0.155316564 18.07190515 0.006863463 0.015393519 4.68E-06 5.329712681 -0.14635632 RTYS(ph)DEANQMR ddPTM_HeLa_Curcumin_4h_R1 1 RTYSDEANQMR 11 1 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 0 RT(0.006)YS(0.994)DEANQMR 148.89 0.0011306 6163500 3040.5 2783.9 3072.3 3255.1 3077.2 3293.9 2154 2061.3 2894.5 2583.5 TRUE FALSE FALSE 2799.841217 3024.527911 3186.162141 3241.631259 3040.5064 2610.70801 2214.435443 2689.780881 2576.980592 2673.276433 1.047344443 1.131393624 1.191856593 1.212606081 1.137370742 0.976594855 0.828360066 1.006173865 0.963978345 1 11.38439331 -5.006341799 23.32849068 1.06521673 0.913569549 0.386564758 0.088320397 112.3748171 413390.8187 0.013758276 0.03922479 9.86E-06 5.006341799 -0.151647181 RVAAPQDGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 RVAAPQDGSPR 11 1 Q9HD15 Q9HD15 SRA1 Steroid receptor RNA activator 1 1 0 RVAAPQDGS(1)PR;RVAAPQDGS(1)PR ; 80.916 0.012649 13572100 5132.3 5592 3979.4 4221.9 4030.2 7008.7 6836.4 2876.6 4159 3497.9 TRUE FALSE FALSE 4726.073039 6075.347563 4126.880065 4204.430896 3982.142497 5555.016616 7028.210985 3753.662098 3702.768105 3619.451765 1.305742788 1.678527014 1.140194796 1.161620922 1.100205986 1.534767411 1.941788824 1.037080293 1.02301905 1 11.82155547 -12.36347065 0.164112914 3.79E-09 1.492919661 0.200445373 0.272714076 47.95584749 0.737110192 16.16838512 0.540209312 4.33E-13 12.36347065 1.492919657 RVAIFIEK ddPTM_HeLa_Curcumin_4h_R1 2 RVAIFIEK 8 1 Q9P258 Q9P258 RCC2 Protein RCC2 0 0 ; ; 123.35 0.00067749 6198300 8839.8 5667.2 7085.4 6025.1 7766.2 9900.4 8090.3 8566.5 6884.5 6722.3 FALSE FALSE TRUE 8140.120502 6157.047515 7347.991157 6000.169733 7673.593137 7846.945439 8317.292044 11178.38641 6129.287574 6955.899425 1.17024701 0.885154764 1.056368229 0.862601565 1.103177701 1.128099324 1.195717698 1.607036809 0.881163916 1 12.76402136 -3.925633243 1.293350505 1.051269261 2.304317458 0.737310048 0.106660103 1.158713962 0.931629565 0.015250137 2.36106872 0.000118677 3.925633243 1.253048197 RVDIIPGFEFDR ddPTM_HeLa_Curcumin_4h_R1 1 RVDIIPGFEFDR 12 1 A6NKB8;Q9H4A4 A6NKB8 RNPEP Aminopeptidase B 0 0 101.32 0.012544 6312600 2022.2 1620.7 1719.8 1666.8 1420.5 3118.2 1993 1696.8 1699.8 1925.6 FALSE FALSE TRUE 1862.140736 1760.786086 1783.537301 1659.903223 1403.561465 2471.450171 2048.918216 2214.146509 1513.336193 1992.514457 0.934568244 0.883700532 0.895118876 0.833069601 0.704417205 1.240367498 1.028307829 1.111232343 0.759510772 1 10.96037448 -5.239960591 24.99517751 0.930442988 1.116803065 0.48566124 0.110093397 634.2168961 738046.3381 0.0146912 0.037418642 5.75E-06 5.239960591 0.186360078 RVES(ph)EES(ph)GDEEGK ddPTM_HeLa_Curcumin_4h_R1 1 RVESEESGDEEGK 13 1 H7C118;C9JRC4;B5MBZ8;C9JD73;Q15435-3;Q15435 H7C118 PPP1R7 Protein phosphatase 1 regulatory subunit 7 2 0 RVES(1)EES(1)GDEEGK 97.273 0.0068207 0 4765.3 4118.9 4544.6 4513 4793.8 4905.1 4232.2 3816.1 3931.8 3951.1 TRUE FALSE FALSE 4388.121477 4474.919363 4713.026874 4494.326402 4736.637066 3887.726968 4350.944142 4979.611323 3500.491377 4088.400431 1.0733101 1.09454038 1.152780153 1.099287234 1.158555075 0.950916387 1.064216731 1.217985226 0.856200716 1 11.99732079 -8.459303035 0.708623371 1.004010157 1.100894783 0.348545668 0.081829271 0.69599193 0.730115094 0.03251188 0.015581845 3.47E-09 8.459303035 0.096884627 RVGDPPQPLPEEPMEVQGAERAS(ph)PEPQR ddPTM_HeLa_Curcumin_4h_R1 1 RVGDPPQPLPEEPMEVQGAERASPEPQR 28 2 P46379-3;P46379;P46379-2;P46379-5;A0A0G2JK23;A0A024RCR6;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 0 RVGDPPQPLPEEPMEVQGAERAS(1)PEPQR 81.65 3.07E-06 28859000 2080.4 2288 2420.5 2149.5 2183.2 2325.2 2028.8 1528.8 1719.9 1938.7 TRUE FALSE FALSE 1915.734145 2485.764525 2510.205859 2140.605939 2157.166766 1842.92731 2085.722668 1994.924082 1531.231273 2006.069681 0.954968894 1.239121726 1.251305417 1.067064599 1.075319959 0.918675621 1.039705992 0.994444062 0.763299145 1 10.970156 RVIISAPSADAPMFVMGVNHEK ddPTM_HeLa_Curcumin_4h_R1 1 RVIISAPSADAPMFVMGVNHEK 22 1 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 77.137 0.0029564 6653400 1643.1 1212.2 1319.4 1179.2 1953.9 3474 1722.8 1008.2 1746.3 1148.1 FALSE FALSE TRUE 1513.046901 1316.977167 1368.298125 1174.320783 1930.601019 2753.45324 1771.137131 1315.595539 1554.735259 1187.99639 1.273612373 1.108570008 1.151769599 0.988488512 1.625089971 2.317728626 1.490860702 1.107407018 1.30870369 1 10.21431474 -5.720068947 8.017417953 1.123659242 1.67609447 0.403863649 0.293757773 0.172802583 28.95928696 0.04267567 0.08507787 1.91E-06 5.720068947 0.552435229 RVLETEEVYSHK ddPTM_HeLa_Curcumin_4h_R1 1 RVLETEEVYSHK 12 1 P34947 P34947 GRK5 G protein-coupled receptor kinase 5 0 0 28.206 0.020329 3756900 2667.7 2140.6 2280.6 2113.2 2407.8 317.31 1752.3 1935.8 2478.2 3119.6 FALSE FALSE TRUE 2456.54873 2325.623926 2365.121042 2104.456138 2379.088558 251.4963292 1801.464822 2526.016509 2206.34766 3228.005868 0.761011234 0.720452199 0.732687963 0.6519369 0.737014942 0.077910741 0.55807359 0.782531573 0.68350175 1 11.65642749 -7.424423809 0.33384631 1.02181784 0.477914977 0.179177741 0.20347867 0.865692558 0.299600181 0.163736126 0.161389654 3.76E-08 7.424423809 -0.543902863 RVNDAEPGS(ph)PEAPQGK ddPTM_HeLa_Curcumin_4h_R1 2 RVNDAEPGSPEAPQGK 16 1 Q8N8A6 Q8N8A6 DDX51 ATP-dependent RNA helicase DDX51 1 0 RVNDAEPGS(1)PEAPQGK;RVNDAEPGS(1)PEAPQGK ; 123.54 0.0011338 30400000 12093.8 10906.8 10543.7 11950.2 10521 13446.5 9878.2 7698.7 12957.5 11409.4 TRUE FALSE FALSE 11136.56297 11849.53519 10934.4588 11900.75324 10395.54395 10657.54433 10155.35571 10045.99819 11536.09467 11805.8758 0.943306804 1.003698107 0.926187856 1.008036459 0.880539836 0.902732208 0.860195031 0.850932058 0.977148571 1 13.52721745 -5.744358211 22.13759956 0.973399474 0.874722981 0.769730369 0.027512361 25.69156737 33295.87784 0.004339031 0.008651226 1.80E-06 5.744358211 -0.098676493 RVNNGNTAPEDSS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 2 RVNNGNTAPEDSSPAK 16 1 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 0 RVNNGNTAPEDS(0.047)S(0.953)PAK;RVNNGNTAPEDS(0.084)S(0.916)PAK ; 152.86 0.00015559 9494800 6742.3 5368.2 5729.1 6644.7 6103.2 6914.3 6138 3316.99 7358.8 6518.5 TRUE FALSE FALSE 6208.639841 5832.203288 5941.425486 6617.205992 6030.423326 5480.19624 6310.21576 4328.324981 6551.558051 6745.01739 0.920477959 0.864668384 0.880861404 0.981050991 0.894056009 0.812480669 0.93553736 0.641707016 0.971318185 1 12.71960645 -2.093920935 0.286659158 0.971431969 1.56E-54 0.542510165 0.067096526 15.58177068 0.348977102 0.027916554 6.841469697 0.008055251 2.093920935 -0.971431969 RVNNGNTAPEDSS(ph)PAKK ddPTM_HeLa_Curcumin_4h_R1 1 RVNNGNTAPEDSSPAKK 17 2 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 0 RVNNGNTAPEDS(0.416)S(0.584)PAKK 70.837 0.0054191 8146300 5792.3 4462.3 5343.9 5381.6 5517.1 6436.6 5104.8 3566.1 5816.1 5240.4 TRUE FALSE FALSE 5333.833343 4848.001328 5541.949635 5359.332365 5451.312186 5101.576605 5248.026949 4653.387474 5178.088381 5422.50351 0.983647744 0.894052225 1.022027856 0.988350188 1.0053128 0.940815731 0.967823615 0.858162187 0.954925778 1 12.40474337 -3.177681999 1.014416438 0.986596503 8.79E-11 0.456096792 0.036141793 7.913585318 1.163662903 0.005089669 14.15781447 0.000664229 3.177681999 -0.986596503 RVNS(ph)GDTEVGSSLLR ddPTM_HeLa_Curcumin_4h_R1 1 RVNSGDTEVGSSLLR 15 1 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 0 RVNS(1)GDTEVGSSLLR 108.77 0.0037176 11352000 2988.3 2624.8 3585.2 2967.4 3080.5 3964.1 3200.6 2498 4416 3075.1 TRUE FALSE FALSE 2751.772902 2851.676016 3718.070666 2955.121685 3043.767049 3141.900975 3290.400222 3259.628701 3931.575848 3181.959496 0.864804503 0.896201231 1.168484599 0.928711283 0.956570017 0.987410738 1.034079857 1.024409237 1.235583248 1 11.63569976 AEAAAS(ph)ALADADADLEER ddPTM_HeLa_Curcumin_4h_R1 1 AEAAASALADADADLEER 18 0 M0R1T5;O43633 M0R1T5 CHMP2A Charged multivesicular body protein 2a 1 0 AEAAAS(1)ALADADADLEER 137.52 0.0002972 2550000 1108.8 722.56 774.86 896.97 949.34 1394.5 1321.9 1525.7 1272.8 896.79 TRUE FALSE FALSE 1021.03731 785.0148667 803.5769932 893.2585758 938.0197405 1105.264981 1358.988956 1990.878907 1133.177024 927.9533857 1.100310992 0.845963686 0.865966982 0.962611473 1.01084791 1.191078127 1.464501318 2.145451417 1.221157271 1 9.857908525 -4.198125668 1.282190503 1.009790766 2.770563582 0.919803653 0.103651469 0.282428873 0.353573886 0.014240587 0.675541847 6.34E-05 4.198125668 1.760772816 up RVPS(ph)PTPAPK ddPTM_HeLa_Curcumin_4h_R1 4 RVPSPTPAPK 10 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 RVPS(0.996)PT(0.004)PAPK;RVPS(0.999)PT(0.001)PAPK;RVPS(0.989)PT(0.011)PAPK;RVPS(0.988)PT(0.012)PAPK ;;; 132.56 0.0040276 4032260000 53476 41962.2 44232 47439 43440 53570 42667 35136.7 49015 42691 TRUE FALSE FALSE 49243.31817 45589.22559 45871.27683 47242.70999 42922.00637 42458.97814 43864.12119 45849.71808 43638.17713 44174.50907 1.114745114 1.032025631 1.038410563 1.069456367 0.971646483 0.961164686 0.992973597 1.037922527 0.987858791 1 15.43092648 -5.762025445 24.99999914 1.053240125 0.98894715 0.241527478 0.03912929 14.9880324 639384.473 0.006830445 0.012949799 1.73E-06 5.762025445 -0.064292975 RVS(ph)EVEEEKEPVPQPLPSDDTR ddPTM_HeLa_Curcumin_4h_R1 3 RVSEVEEEKEPVPQPLPSDDTR 22 2 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 1 0 RVS(0.997)EVEEEKEPVPQPLPS(0.003)DDTR;RVS(0.998)EVEEEKEPVPQPLPSDDT(0.002)R;RVS(0.998)EVEEEKEPVPQPLPS(0.001)DDTR ;; 59.792 0.0072712 168814000 5340 4707.2 5559.9 5174.6 5846.6 6242.1 6491 7881.2 5222.5 4519.5 TRUE FALSE FALSE 4917.333365 5114.069393 5765.954785 5153.188876 5776.883114 4947.418097 6673.11999 10284.1416 4649.604816 4676.552289 1.051486878 1.093555482 1.232949923 1.101920509 1.235286758 1.057919979 1.426931547 2.1990862 0.994237748 1 12.1912296 RVS(ph)GDAAQDLDR ddPTM_HeLa_Curcumin_4h_R1 3 RVSGDAAQDLDR 12 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 RVS(1)GDAAQDLDR;RVS(1)GDAAQDLDR;RVS(1)GDAAQDLDR ;; 108.06 0.002885 70582000 6066.9 5388.3 5865.8 5899.4 5386.3 6231.8 4233.44 2489.65 6106.5 6052 TRUE FALSE FALSE 5586.698463 5854.040642 6083.191708 5874.989846 5322.07189 4939.254433 4352.218933 3248.732824 5436.632228 6262.30655 0.892115137 0.934805825 0.971397944 0.938151111 0.849858091 0.788727667 0.694986567 0.518775758 0.868151724 1 12.61247842 -3.86184105 0.608984081 0.95328315 3.92E-17 0.918413813 0.03953836 0.969445314 0.175571761 0.007599464 0.721640916 0.000137454 3.86184105 -0.95328315 RVS(ph)LSEIGFGK ddPTM_HeLa_Curcumin_4h_R1 2 RVSLSEIGFGK 11 1 H0YBX5;E5RJM2;E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2 H0YBX5 CDK16 Cyclin-dependent kinase 16 1 0 RVS(0.999)LS(0.001)EIGFGK;RVS(0.994)LS(0.006)EIGFGK ; 119 0.0020292 260280000 15185.3 13483.6 13725.2 13223.4 14868.8 19853.9 15577.1 11371.2 15013.1 12579 TRUE FALSE FALSE 13983.36748 14649.0623 14233.86799 13168.68507 14691.49927 15735.97734 16014.1515 14838.22653 13366.20049 13016.11931 1.074311563 1.125455441 1.093556969 1.011721294 1.128715781 1.208960748 1.230332261 1.139988515 1.026895972 1 13.66801176 -1 0.114985147 0.946740531 1.758912192 0.591668915 0.047652095 47.39678726 0.378418587 0.253710376 6.16056489 0.1 1 0.812171661 RVS(ph)LVGADDLR ddPTM_HeLa_Curcumin_4h_R1 1 RVSLVGADDLR 11 1 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 RVS(1)LVGADDLR 73.758 0.016595 5933200 2392.6 1862.9 2376.6 3133.8 2333.3 3505.8 2266.3 1150.1 3304.8 2305.8 TRUE FALSE FALSE 2203.223185 2023.920775 2464.678887 3120.833166 2305.476921 2778.657561 2329.886279 1500.760196 2942.271708 2385.926378 0.923424631 0.848274613 1.033007099 1.308017378 0.966281668 1.164603228 0.976512226 0.629005241 1.233177911 1 11.22033381 -4.265776496 5.630019965 0.997670718 0.6174021 0.391846636 0.144841441 0.102741683 13.26540101 0.017787911 0.149546255 5.42E-05 4.265776496 -0.380268618 RVS(ph)PLNLSSVT(ph)P ddPTM_HeLa_Curcumin_4h_R1 3 RVSPLNLSSVTP 12 1 Q9UJX2;Q9UJX2-3 Q9UJX2 CDC23 Cell division cycle protein 23 homolog 2 0 RVS(1)PLNLSSVT(1)P;RVS(0.997)PLNLS(0.002)S(0.001)VT(1)P;RVS(1)PLNLSS(0.001)VT(0.999)P ;; 115.91 0.0062689 49763000 12615.6 10205 11409 10873.2 9559 10196.5 6280.8 6651 12809.6 11586 TRUE FALSE FALSE 11617.06195 11087.07473 11831.82758 10828.20958 9445.015168 8081.630962 6457.022344 8678.859283 11404.41893 11988.61264 0.969008033 0.92480048 0.986922168 0.903207895 0.787832208 0.67410894 0.538596295 0.72392524 0.95127095 1 13.54937709 -5.593520139 1.494314711 0.980440578 0.623774297 0.894821687 0.048277809 0.075168166 0.331680701 0.006870008 0.019189933 2.55E-06 5.593520139 -0.356666281 RVS(ph)STWTTTTSATGLPTLEPAPVRR ddPTM_HeLa_Curcumin_4h_R1 1 RVSSTWTTTTSATGLPTLEPAPVRR 25 2 Q14432 Q14432 PDE3A "cGMP-inhibited 3,5-cyclic phosphodiesterase A" 1 0 RVS(0.674)S(0.045)T(0.045)WT(0.045)T(0.045)T(0.045)T(0.045)S(0.051)AT(0.008)GLPTLEPAPVRR 63.085 0.0021634 35229000 210.43 167.28 208.44 237.66 175.75 229.59 186.89 240.94 252.59 252.58 TRUE FALSE FALSE 193.7742435 181.7389378 216.1649698 236.6766259 173.654296 181.970446 192.1336304 314.4014968 224.8815089 261.3571362 0.741415545 0.695366273 0.827086541 0.905567873 0.664432962 0.696252066 0.73513826 1.202957384 0.860437607 1 8.029878742 -9.34501046 1.064692011 1.000185092 0.79421876 0.057723126 0.154959315 0.641502566 1.299714278 0.098512687 0.025705711 4.52E-10 9.34501046 -0.205966332 RVS(ph)VCAETYNPDEEEEDTDPR ddPTM_HeLa_Curcumin_4h_R1 7 RVSVCAETYNPDEEEEDTDPR 21 1 P13861-2;P13861 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 1 0 RVS(0.993)VCAET(0.005)Y(0.001)NPDEEEEDT(0.001)DPR;RVS(0.999)VCAET(0.001)YNPDEEEEDTDPR;RVS(1)VCAETYNPDEEEEDTDPR;RVS(0.985)VCAET(0.013)Y(0.002)NPDEEEEDTDPR;RVS(0.989)VCAET(0.011)YNPDEEEEDTDPR;RVS(1)VCAETYNPDEEEEDTDPR;RVS(0.985)VCAET(0.011)Y(0.004)NPDEEEEDTDPR ;;;;;; 124.1 7.01E-06 2262844000 7727.41 6782.74 6906.58 8236.4 7221.75 8897.14 6056.63 5649.03 8389.11 8096.45 TRUE FALSE FALSE 7115.777345 7369.009822 7162.54393 8202.319959 7135.635348 7051.772873 6226.562737 7371.393242 7468.845622 8377.801035 0.849360986 0.87958759 0.854943189 0.979054041 0.851731298 0.841721216 0.743221606 0.879872082 0.891504297 1 13.03235591 -13.52287875 0.20404805 1.696593791 0.830762191 0.147985319 0.063145702 31.29654626 0.383606563 8.679476618 0.053745315 3.00E-14 13.52287875 -0.8658316 RVSGPDPKPGSNCSPAQSVLS(ph)EVPSVPTNGMAK ddPTM_HeLa_Curcumin_4h_R1 1 RVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAK 33 2 P22314;Q5JRR9;Q5JRS0;Q5JRS2;Q5JRS1;Q5JRS3 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 1 0 RVS(0.014)GPDPKPGS(0.085)NCS(0.085)PAQS(0.283)VLS(0.44)EVPS(0.076)VPT(0.017)NGMAK 42.367 0.0078425 223110000 3028 2322.9 2465.2 2697.6 2253.2 2953.5 2330 2821.4 2525.1 2458 TRUE FALSE FALSE 2788.330605 2523.681125 2556.562481 2686.438046 2226.332062 2340.910807 2395.373529 3681.631872 2248.102847 2543.415317 1.096293864 0.992241066 1.005169098 1.05623255 0.875331703 0.920380872 0.941794096 1.447515019 0.883891369 1 11.31255135 -4.255369196 24.82778903 1.015934882 1.447515229 0.753417148 0.078003122 243.6635898 996582.0793 0.010779012 0.132208227 5.55E-05 4.255369196 0.431580347 RVTFGEDLS(ph)PEVFDESLPANTPLR ddPTM_HeLa_Curcumin_4h_R1 1 RVTFGEDLSPEVFDESLPANTPLR 24 1 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 0 RVT(0.002)FGEDLS(0.997)PEVFDES(0.001)LPANTPLR 73.981 0.00031739 2785900 868.37 706.72 631.91 702.27 903.77 980.32 606.92 471.61 917.77 765.7 TRUE FALSE FALSE 799.6375982 767.8057277 655.3291405 699.3641928 892.993133 776.9905815 623.9485418 615.401718 817.0929271 792.308018 1.009250923 0.969074792 0.827114109 0.882692308 1.127078248 0.980667321 0.787507545 0.776720296 1.031281911 1 9.629917592 -4.761340653 6.419754632 0.988293659 0.780041418 0.507304398 0.076942941 0.079534169 14.18296552 0.010985734 0.037590508 1.73E-05 4.761340653 -0.208252241 RVTQHES(ph)DNENEIQIQNK ddPTM_HeLa_Curcumin_4h_R1 1 RVTQHESDNENEIQIQNK 18 1 Q5VZL5-2;Q5VZL5-4;Q5VZL5 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 0 RVT(0.128)QHES(0.872)DNENEIQIQNK 72.864 0.0055411 6141100 1965.5 1527.8 1924.1 1608.8 1614.8 2467.8 1381.2 730.97 2287.1 2002.5 TRUE FALSE FALSE 1809.928601 1659.856224 1995.408839 1602.143212 1595.544565 1955.950462 1419.952755 953.839388 2036.210852 2072.086726 0.873481104 0.801055382 0.962994847 0.773202778 0.770018236 0.943952026 0.6852767 0.460327927 0.982686114 1 11.01686867 -3.794582214 0.587644228 0.927240132 1.12E-214 0.688424535 0.088225583 2.542291584 0.407851078 0.017145459 1.809040038 0.000160479 3.794582214 -0.927240132 RVVGCLIAEPIK ddPTM_HeLa_Curcumin_4h_R1 1 RVVGCLIAEPIK 12 1 Q56NI9;Q56NI9-2 Q56NI9;Q56NI9-2 ESCO2 N-acetyltransferase ESCO2 0 0 31.639 0.0192 1254100 1321.9 875.22 1030.8 1922.8 1127.9 3371.8 1617.5 860.27 2533.2 1309.2 FALSE FALSE TRUE 1217.27022 950.8701169 1069.002355 1914.843963 1114.450529 2672.450672 1662.882697 1122.562363 2255.314298 1354.694603 0.898556928 0.701907364 0.789109481 1.413487556 0.822658131 1.972732944 1.227496362 0.828646073 1.664813821 1 10.40375194 -6.263217648 24.97140418 0.917022331 1.267663926 0.061808834 0.392405619 175.7588001 2468102.161 0.04597397 0.072504235 5.45E-07 6.263217648 0.350641595 RVVLGDGVQLPPGDYST(ph)T(ph)PGGTLFSTTPGGTR ddPTM_HeLa_Curcumin_4h_R1 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 0 RVVLGDGVQLPPGDY(0.099)S(0.2)T(0.457)T(0.458)PGGT(0.085)LFS(0.221)T(0.221)T(0.232)PGGT(0.027)R 51.463 0.0028004 33089000 854.25 739.76 744.05 650.69 675.58 875.79 630.93 864.51 741.21 918.94 TRUE FALSE FALSE 786.6352111 803.7015581 771.6251475 647.9976172 667.5241497 694.1412818 648.6321977 1128.095119 659.9011174 950.8730966 0.827276756 0.845224837 0.811491197 0.681476445 0.702011816 0.730004124 0.682143811 1.186378207 0.69399494 1 9.893109002 -8.714192558 0.594700363 1.006167274 0.786975688 0 0.168146624 0.94541848 0.634808376 0.102937248 0.033869727 1.93E-09 8.714192558 -0.219191585 RVVLGDGVQLPPGDYST(ph)TPGGTLFS(ph)TTPGGTR ddPTM_HeLa_Curcumin_4h_R1 5 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 0 RVVLGDGVQLPPGDY(0.036)S(0.183)T(0.415)T(0.415)PGGT(0.152)LFS(0.486)T(0.148)T(0.152)PGGT(0.013)R;RVVLGDGVQLPPGDY(0.032)S(0.174)T(0.411)T(0.411)PGGT(0.108)LFS(0.269)T(0.269)T(0.271)PGGT(0.056)R;RVVLGDGVQLPPGDY(0.018)S(0.018)T(0.482)T(0.482)PGGT(0.046)LFS(0.313)T(0.313)T(0.315)PGGT(0.014)R;RVVLGDGVQLPPGDY(0.025)S(0.108)T(0.387)T(0.387)PGGT(0.155)LFS(0.282)T(0.282)T(0.282)PGGT(0.092)R;RVVLGDGVQLPPGDY(0.014)S(0.034)T(0.428)T(0.428)PGGT(0.17)LFS(0.302)T(0.302)T(0.305)PGGT(0.017)R ;;;; 78.311 1.42E-06 451531000 8276.4 7109.5 7019.9 7861.6 7814.4 8923.58 6739.4 6589.4 8486.9 7124.9 TRUE FALSE FALSE 7621.314207 7724.013501 7280.063669 7829.070782 7721.218384 7072.728919 6928.489426 8598.477726 7555.908303 7372.489745 1.033750398 1.047680467 0.987463384 1.061930373 1.047301339 0.959340625 0.939776068 1.16629226 1.024878781 1 12.8479362 -4.242746745 24.76594733 1.014028336 1.166292411 0.598569829 0.03800986 2167.852653 2872147.457 0.005281597 0.25836887 5.72E-05 4.242746745 0.152264075 RVVLGDGVQLPPGDYST(ph)TPGGTLFS(ph)TTPGGTRIIYDRK ddPTM_HeLa_Curcumin_4h_R1 1 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRK 38 3 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 0 RVVLGDGVQLPPGDY(0.09)S(0.098)T(0.343)T(0.343)PGGT(0.196)LFS(0.276)T(0.276)T(0.276)PGGT(0.048)RIIY(0.053)DRK 71.903 1.04E-06 29100000 1156.4 834.12 865.77 908.23 712.97 1150.1 631.2 676.93 1594.7 1209.8 TRUE FALSE FALSE 1064.86972 906.217616 897.8561978 904.4719849 704.4682984 911.5562957 648.9097732 883.3228408 1419.7654 1251.84046 0.850643316 0.723908234 0.717228933 0.722513782 0.562746069 0.728172898 0.518364595 0.705619341 1.134142445 1 10.289835 -7.396203008 0.478402973 0.994805104 0.609955595 0.795860049 0.079704904 0.216148447 0.123075148 0.026168542 0.027360564 4.02E-08 7.396203008 -0.384849509 RVVLGDGVQLPPGDYSTT(ph)PGGTLFS(ph)TTPGGTR ddPTM_HeLa_Curcumin_4h_R1 4 RVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 32 1 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 0 RVVLGDGVQLPPGDY(0.01)S(0.034)T(0.105)T(0.817)PGGT(0.069)LFS(0.315)T(0.315)T(0.315)PGGT(0.018)R;RVVLGDGVQLPPGDY(0.008)S(0.033)T(0.154)T(0.74)PGGT(0.16)LFS(0.28)T(0.28)T(0.282)PGGT(0.062)R;RVVLGDGVQLPPGDY(0.131)S(0.139)T(0.124)T(0.518)PGGT(0.153)LFS(0.304)T(0.291)T(0.26)PGGT(0.08)R;RVVLGDGVQLPPGDY(0.071)S(0.079)T(0.211)T(0.579)PGGT(0.128)LFS(0.29)T(0.29)T(0.29)PGGT(0.062)R ;;; 79.021 1.05E-06 207288000 4402.64 3832.14 3938.08 4129.37 3875.02 5340.35 4399.46 3537.62 4629.01 4238.93 TRUE FALSE FALSE 4054.166398 4163.373106 4084.028709 4112.283761 3828.812917 4232.701212 4522.897007 4616.224053 4121.219184 4386.232502 0.924293547 0.949191158 0.931101739 0.937543498 0.872916088 0.964997001 1.031157606 1.052434875 0.93958065 1 12.09876657 -4.749547315 3.942740023 0.95136313 1.046267173 0.611304887 0.0317676 0.142913518 4.839022661 0.005675222 0.021991452 1.78E-05 4.749547315 0.094904043 KSTGSPT(ph)QETQAPFIAK ddPTM_HeLa_Curcumin_4h_R1 1 KSTGSPTQETQAPFIAK 17 1 O15231-3;H0Y704;O15231-2 O15231-3 ZNF185 Zinc finger protein 185 1 0 KS(0.082)T(0.082)GS(0.082)PT(0.71)QET(0.044)QAPFIAK 82.586 0.004236 35018000 2604 2132 1959.3 2349.4 1867.1 3204.9 2912.8 4235.2 2811.8 2298.3 TRUE FALSE FALSE 2397.890652 2316.28058 2031.913382 2339.678805 1844.836052 2540.167613 2994.525329 5526.492984 2503.352575 2378.165754 1.008294165 0.973977771 0.8544036 0.983816541 0.775739054 1.068120508 1.259174355 2.323846845 1.052640074 1 11.21563356 -4.197127101 2.047705224 0.975718503 2.860093817 0.960182333 0.083012291 0.116541537 0.456858939 0.011637313 0.430648629 6.35E-05 4.197127101 1.884375313 up RWDDDVVFK ddPTM_HeLa_Curcumin_4h_R1 2 RWDDDVVFK 9 1 Q9P013 Q9P013 CWC15 Spliceosome-associated protein CWC15 homolog 0 0 ; ; 159.34 0.0012433 34804000 7620.6 6633.3 6188.1 6932.7 6166 8213.4 6666.2 5478.8 8272.9 7755.2 FALSE FALSE TRUE 7017.421469 7206.652895 6417.43643 6904.014324 6092.474477 6509.848256 6853.235631 7149.260899 7365.383568 8024.692623 0.874478538 0.898059681 0.799711183 0.860346265 0.759215931 0.811227116 0.854018459 0.890907756 0.917839961 1 12.97023042 -8.599770789 0.472268965 1.013782169 0.827168571 0.502433106 0.045349542 0.464807694 0.200975173 0.039091135 0.012774922 2.51E-09 8.599770789 -0.186613598 RWDNDDMTDDIPES(ph)SLFSPMPSEEK ddPTM_HeLa_Curcumin_4h_R1 1 RWDNDDMTDDIPESSLFSPMPSEEK 25 1 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 0 RWDNDDMT(0.023)DDIPES(0.344)S(0.296)LFS(0.256)PMPS(0.081)EEK 40.428 0.01454 6767700 1009.7 792.09 917.2 942.28 1040.9 1314 1398.1 626.63 1040.6 765.77 TRUE FALSE FALSE 929.7811796 860.5547301 951.1922389 938.381095 1028.487947 1041.461588 1437.326923 817.6866024 926.4487835 792.3804505 1.173402472 1.086037306 1.200423658 1.184255738 1.29797239 1.314345385 1.813935367 1.031936871 1.169196922 1 9.630049476 -6.024894724 0.472106238 1.051255722 1.4654844 0.242992185 0.189696568 1.052932334 0.406043927 0.050685236 0.189859693 9.44E-07 6.024894724 0.414228678 RWDQTADQT(ph)PGAT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 RWDQTADQTPGATPK 15 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 2 0 RWDQTADQT(1)PGAT(1)PK 72.932 0.0091819 33381000 5174.8 4018.6 4111.2 5148.2 4796.8 6280.2 4432.5 2152.1 5795.9 5323.1 TRUE FALSE FALSE 4765.20912 4365.949877 4263.564689 5126.898112 4739.601293 4977.615728 4556.864021 2808.265383 5160.104271 5508.077329 0.865131122 0.792644986 0.774056796 0.930796321 0.860481981 0.903693872 0.827305745 0.509844945 0.93682495 1 12.4273331 -1 0.101093676 1.079298261 0.026689749 0.414389454 0.098024409 91.80385407 0.660572362 0.790654364 13.47205734 0.1 1 -1.052608512 RWDQTADQT(ph)PGATPK ddPTM_HeLa_Curcumin_4h_R1 1 RWDQTADQTPGATPK 15 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 RWDQTADQT(0.928)PGAT(0.071)PK 67.115 0.017698 108710000 5073.3 3785.5 4264.8 4918.1 4431.6 5939.8 4588.4 2312.1 4896.3 3725.7 TRUE FALSE FALSE 4671.742952 4112.701752 4422.85724 4897.750205 4378.756064 4707.818525 4717.138155 3017.048646 4359.18814 3855.167798 1.211813129 1.066802269 1.147254146 1.270437621 1.13581465 1.221170847 1.223588285 0.782598529 1.130738886 1 11.91257794 -4.251754874 24.48353734 1.130821988 0.782598277 0.65075999 0.080205033 628.8600559 1589786.605 0.014143636 0.24094436 5.60E-05 4.251754874 -0.348223711 RWDQTADQTPGAT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 RWDQTADQTPGATPK 15 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 RWDQTADQT(0.013)PGAT(0.987)PK;RWDQTADQT(0.014)PGAT(0.986)PK ; 147.09 0.0017971 38438400 7540.3 6355.4 6266.8 7191.9 7055.7 9149.7 7214.7 3280.3 7654.3 7010.6 TRUE FALSE FALSE 6943.477299 6904.732457 6499.053121 7162.141823 6971.565386 7251.949082 7417.125065 4280.448369 6814.64244 7254.217828 0.957164158 0.951823149 0.895899913 0.987307246 0.961036124 0.999687251 1.022456899 0.590063391 0.939404165 1 12.82460435 -4.257098552 24.99968065 0.974655673 0.590063238 0.913411923 0.034888179 88.7455944 511084.5075 0.004868674 0.051343672 5.53E-05 4.257098552 -0.384592434 RWS(ph)WGGSAMANSESK ddPTM_HeLa_Curcumin_4h_R1 2 RWSWGGSAMANSESK 15 1 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 0 RWS(1)WGGSAMANSESK;RWS(0.999)WGGS(0.001)AMANSESK ; 114.01 0.0028453 27440000 2353.77 1724.36 1904.55 2136.35 2166.67 3308.2 2742 1047.1 2497.5 2100.74 TRUE FALSE FALSE 2167.466621 1873.405995 1975.134298 2127.51035 2140.833875 2622.042029 2818.93314 1366.35597 2223.530498 2173.740559 0.99711376 0.861835138 0.908633871 0.978732416 0.984861725 1.20623504 1.296812138 0.628573619 1.02290519 1 11.08596405 -5.47670174 24.91775282 0.97859424 1.073564305 0.031032793 0.169336833 913.8851484 493144.1394 0.022297958 0.049857964 3.34E-06 5.47670174 0.094970064 RY(ph)NFPVEVEVPMER ddPTM_HeLa_Curcumin_4h_R1 1 RYNFPVEVEVPMER 14 1 P78527-2;P78527 P78527-2 PRKDC DNA-dependent protein kinase catalytic subunit 1 0 RY(1)NFPVEVEVPMER 52.576 0.01787 16619000 2835.2 2659.2 2909 3059.6 2738.4 3733 2869.6 2918.8 2961.5 2577.6 TRUE FALSE FALSE 2610.790928 2889.049399 3016.810099 3046.940186 2705.746369 2958.73372 2950.113253 3808.728683 2636.630859 2667.171408 0.978861321 1.083188501 1.131089697 1.142386341 1.014462873 1.109315176 1.106083113 1.428002967 0.988549462 1 11.38109483 -1 0.596001243 1.010958556 24.17961121 0.735289095 0.064082764 58.7260711 0.424248007 0.012383735 1775.293403 0.1 1 23.16865265 RY(ph)SYLT(ph)EPGMT(ph)S(ph)CTVK ddPTM_HeLa_Curcumin_4h_R1 1 RYSYLTEPGMTSCTVK 16 1 Q12955-7 Q12955-7 ANK3 Ankyrin-3 4 0 RY(0.532)S(0.441)Y(0.388)LT(0.638)EPGMT(0.883)S(0.883)CT(0.235)VK 56.529 0.011889 2654400 723.68 668.33 784.71 817.89 844.99 743.96 829 699.75 625.52 478.01 TRUE FALSE FALSE 666.3999644 726.0974672 813.7920429 814.5057879 834.9140461 589.6543098 852.2595089 913.1005537 556.902021 494.6208119 1.347294631 1.467988103 1.645284677 1.646727692 1.687988103 1.192134046 1.723056306 1.846061734 1.125917081 1 8.950179134 -8.04162624 0.422131345 0.963396264 1.659708928 0.632663946 0.165591306 0.469248797 0.206689382 0.133690401 0.074703955 9.09E-09 8.04162624 0.696312663 RYAS(ph)GSSASLGGPESAVA ddPTM_HeLa_Curcumin_4h_R1 1 RYASGSSASLGGPESAVA 18 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 RYAS(0.555)GS(0.19)S(0.19)AS(0.065)LGGPESAVA 81.713 0.0091394 7205800 1573 1355.5 1472.3 1485 1266 2336.3 1393.8 1067.2 1981 1453.1 TRUE FALSE FALSE 1448.49539 1472.66338 1526.864733 1478.855463 1250.903777 1851.725044 1432.906277 1392.584367 1763.689256 1503.595117 0.963354678 0.979428148 1.015475986 0.983546333 0.831941899 1.231531696 0.952986785 0.926169786 1.1729815 1 10.55420042 RYASGSSAS(ph)LGGPESAVA ddPTM_HeLa_Curcumin_4h_R1 1 RYASGSSASLGGPESAVA 18 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 RYAS(0.001)GS(0.017)S(0.017)AS(0.956)LGGPES(0.008)AVA 104.16 0.0016969 9676600 1604.1 951.88 1466.7 1927.7 1778.1 2846.9 1951.2 1912.4 1481.5 2035.5 TRUE FALSE FALSE 1477.133792 1034.156266 1521.057192 1919.723688 1756.897319 2256.420849 2005.945421 2495.481956 1318.983157 2106.233473 0.701315315 0.490997925 0.722169319 0.911448665 0.834141771 1.071306138 0.952385121 1.184807851 0.626228371 1 11.04044965 -5.188265001 1.409792548 0.815266422 1.095698356 0.436391718 0.153026249 0.481233418 1.732033492 0.026870922 0.115318165 6.48E-06 5.188265001 0.280431934 RYDDPEVQK(ac)DIK ddPTM_HeLa_Curcumin_4h_R1 2 RYDDPEVQKDIK 12 2 P38646;D6RJI2;A0A3B3ITI4 P38646 HSPA9 "Stress-70 protein, mitochondrial" 0 1 ; RYDDPEVQK(1)DIK;RYDDPEVQK(1)DIK 109 0.00083636 15332400 4634.1 4390.8 4626.5 5207.9 4920.5 6939.3 4567.3 4947.6 6148.4 4255 FALSE TRUE FALSE 4267.306095 4770.321187 4797.96216 5186.35109 4861.826251 5500.010958 4695.446146 6456.100464 5473.935903 4402.860933 0.969212101 1.083459428 1.089737385 1.177950239 1.10424252 1.249190252 1.06645343 1.466342127 1.243267954 1 12.10422556 -1 0.265115749 0.972639653 3.662611124 0.288658468 0.116701034 19.46546302 0.246078635 0.037650189 24.11778813 0.1 1 2.68997147 RYEDDGIS(ph)DDEIEGK ddPTM_HeLa_Curcumin_4h_R1 2 RYEDDGISDDEIEGK 15 1 I3VM54;Q9Y2K7-3;Q9Y2K7 I3VM54 KDM2A Lysine-specific demethylase 2A 1 0 RYEDDGIS(1)DDEIEGK;RYEDDGIS(1)DDEIEGK ; 228.46 1.35E-20 36846000 8544.7 6507.6 8050.5 7658.8 8102.7 8695 6652.5 5174.1 7003.1 6353.2 TRUE FALSE FALSE 7868.377979 7070.087947 8348.858612 7627.109915 8006.080595 6891.558987 6839.151246 6751.659271 6234.877451 6573.973227 1.196898391 1.075466495 1.269986707 1.160197897 1.217845026 1.048309561 1.040337557 1.027028714 0.948418443 1 12.68254987 -5.03214821 24.20304728 1.120119729 1.036343165 0.15250518 0.092476091 665.0846123 500715.1939 0.013713699 0.035005514 9.29E-06 5.03214821 -0.083776565 RYEEIVK ddPTM_HeLa_Curcumin_4h_R1 1 RYEEIVK 7 1 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 0 84.498 0.012409 7558700 4034 3385.3 3681.7 3580.2 4136.5 4001.7 2765 2559.6 3666.5 3748.1 FALSE FALSE TRUE 3714.704643 3677.910247 3818.147041 3565.386081 4087.174939 3171.702312 2842.578458 3340.010257 3264.294123 3878.346196 0.957806358 0.948319222 0.984478138 0.919305782 1.053844792 0.817797626 0.732935719 0.86119446 0.841671671 1 11.92122587 -5.1576263 6.106848061 0.976971552 0.792836941 0.555646949 0.061476246 0.073562236 3.6662706 0.005734537 0.014867503 6.96E-06 5.1576263 -0.184134611 RYFGGTEDR ddPTM_HeLa_Curcumin_4h_R1 3 RYFGGTEDR 9 1 Q16658 Q16658 FSCN1 Fascin 0 0 ;; ;; 112.11 0.01241 12796000 5153.37 3976.04 4999.23 4708.5 4348.97 6998.7 4279.06 4405.85 5294.08 4858 FALSE FALSE TRUE 4745.475327 4319.711181 5184.505862 4689.017475 4297.111373 5547.090728 4399.118907 5749.173383 4713.332669 5026.815138 0.944032195 0.859333606 1.031369907 0.932800858 0.854837756 1.103500044 0.875130433 1.143700977 0.937637956 1 12.29542892 -4.242507233 24.08555754 0.962422326 1.143701244 0.360400635 0.075973858 2117.66932 2694040.37 0.009507718 0.427142183 5.72E-05 4.242507233 0.181278917 RYFQT(ph)T(ph)LTPVES(ph)EANTSK ddPTM_HeLa_Curcumin_4h_R1 1 RYFQTTLTPVESEANTSK 18 1 Q8N9W8-2;Q8N9W8 Q8N9W8-2 FAM71D Protein FAM71D 3 0 RY(0.308)FQT(0.822)T(0.864)LT(0.007)PVES(0.495)EANT(0.264)S(0.239)K 50.539 0.011657 77286000 2435.1 3927 4027.5 3161.7 2596.3 3066.5 3325.8 2773.4 3506 5525 TRUE FALSE FALSE 2242.359265 4266.432382 4176.762693 3148.617723 2565.340818 2430.473333 3419.112997 3618.996893 3121.400572 5716.993339 0.392227021 0.746272058 0.730587294 0.550747139 0.448722023 0.425131392 0.598061392 0.633024508 0.545986393 1 12.48104089 -9.453447745 1.096678019 1.00901022 0.552151605 0 0.178948076 0.270407649 0.56294467 0.09789288 0.022407022 3.52E-10 9.453447745 -0.456858615 RYPSS(ph)ISSS(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 1 RYPSSISSSPQK 12 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 2 0 RYPS(0.158)S(0.501)IS(0.34)S(0.076)S(0.924)PQK 97.957 0.016024 33862000 6399.6 6378.1 7328.6 7472.6 9331.7 8637.3 6802 4902.4 6509.8 5966 TRUE FALSE FALSE 5893.064907 6929.394544 7600.204363 7441.680361 9220.425572 6845.826618 6992.845813 6397.119192 5795.691227 6173.318056 0.954602509 1.122474896 1.231137663 1.205458765 1.493593152 1.108937942 1.132753205 1.036252974 0.938829196 1 12.59183041 -7.077734864 3.362510139 0.978707912 1.206760755 0.459976832 0.114093845 0.168146048 3.677937387 0.019519053 0.024546888 8.36E-08 7.077734864 0.228052843 RYPSSISS(ph)SPQK ddPTM_HeLa_Curcumin_4h_R1 1 RYPSSISSSPQK 12 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 0 RYPSSISS(0.5)S(0.5)PQK 101.75 0.003899 9924000 2877.2 2164.6 2886.1 2828.6 3339.6 3239.1 2737.4 1956.6 2536.6 2262.4 TRUE FALSE FALSE 2649.466584 2351.698379 2993.061405 2816.896003 3299.777451 2567.274148 2814.204077 2553.158333 2258.341326 2341.018232 1.131758202 1.00456218 1.278529729 1.203278114 1.409547951 1.096648507 1.202128219 1.090618731 0.964683357 1 11.19292045 -7.928171214 0.546184545 1.011506829 1.207105909 0.380970744 0.103408234 0.645632345 0.454528356 0.049948604 0.033533918 1.18E-08 7.928171214 0.19559908 RYPSSISS(ph)SPQKDLTQAK ddPTM_HeLa_Curcumin_4h_R1 1 RYPSSISSSPQKDLTQAK 18 2 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 0 RYPS(0.005)S(0.007)IS(0.022)S(0.604)S(0.359)PQKDLT(0.003)QAK 75.608 0.0068005 907220000 1300.3 1051 927.94 1273.4 1128.6 1304 1020.9 755.12 1350.9 1329.5 TRUE FALSE FALSE 1197.379883 1141.843757 962.3302727 1268.131008 1115.142182 1033.535701 1049.543706 985.3526119 1202.70965 1375.700026 0.870378615 0.830009257 0.699520429 0.921807795 0.810599812 0.751279844 0.762916106 0.716255429 0.874252836 1 10.42595021 -13.52287873 0.071884761 1.798780142 0.518981827 0.416617332 0.068977488 82.41004469 0.45919548 10.74678346 1.472625635 3.00E-14 13.52287873 -1.279798315 RYPSSISSS(ph)PQKDLTQAK ddPTM_HeLa_Curcumin_4h_R1 1 RYPSSISSSPQKDLTQAK 18 2 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 0 RYPS(0.002)S(0.002)IS(0.01)S(0.179)S(0.806)PQKDLT(0.001)QAK 69.986 0.0041686 1183000000 4361.3 3325.5 3884.5 3642.9 3366.4 4820.6 3912.3 2935.3 4315.7 3470.8 TRUE FALSE FALSE 4016.098503 3612.941402 4028.462987 3627.826645 3326.257879 3820.753221 4022.068609 3830.259458 3842.278507 3591.410042 1.118251176 1.005995239 1.12169397 1.010139918 0.926170457 1.063858812 1.119913505 1.066505749 1.06985236 1 11.81033466 -9.731720994 1.659638497 1.000024087 1.063141063 0 0.062467577 0.668300429 3.3287497 0.045233447 0.00986057 1.85E-10 9.731720994 0.063116977 RYS(ph)DFEWLK ddPTM_HeLa_Curcumin_4h_R1 2 RYSDFEWLK 9 1 A0A087X0R6;Q9UMY4-3;Q9UMY4;Q9UMY4-1 A0A087X0R6 SNX12 Sorting nexin-12 1 0 RYS(1)DFEWLK;RYS(1)DFEWLK ; 131.79 0.0017046 57927000 7566.4 6673.3 7940.6 8173.9 8702.4 8980.1 8051 8809.2 7410.5 6381.3 TRUE FALSE FALSE 6967.511456 7250.110316 8234.885621 8140.078568 8598.629564 7117.526033 8276.889392 11495.08453 6597.58669 6603.0497 1.055195973 1.097994207 1.247133672 1.232775602 1.302220936 1.077914957 1.253494941 1.740875058 0.999172654 1 12.68891679 -1 0.354634075 1.029382512 7.920481402 0.698756783 0.114572701 23.02164861 0.287204415 0.033643318 107.9458403 0.1 1 6.89109889 RYS(ph)DFEWLR ddPTM_HeLa_Curcumin_4h_R1 4 RYSDFEWLR 9 1 O60493-4;O60493;O60493-3 O60493-4 SNX3 Sorting nexin-3 1 0 RY(0.046)S(0.954)DFEWLR;RY(0.011)S(0.989)DFEWLR;RY(0.092)S(0.908)DFEWLR;RY(0.002)S(0.998)DFEWLR ;;; 113.99 0.003685 50787000 9223.7 7213.9 8212.8 8842.3 8468.3 12187.5 9609.3 7488.4 8795.5 8322.7 TRUE FALSE FALSE 8493.634412 7837.437371 8517.173593 8805.712906 8367.321053 9659.675119 9878.911096 9771.578688 7830.655655 8611.913206 0.986265677 0.910069248 0.988999005 1.022503675 0.971598396 1.121664244 1.147121535 1.134658287 0.909281767 1 13.07211806 -5.217096479 5.283511492 0.987517736 1.138140665 0.796351548 0.037438695 0.05620548 3.872891752 0.004122489 0.010614747 6.07E-06 5.217096479 0.150622929 RYS(ph)GDSDSSASSAQSGPLGTR ddPTM_HeLa_Curcumin_4h_R1 3 RYSGDSDSSASSAQSGPLGTR 21 1 A0A5E8;Q99501 A0A5E8 GAS2L1 GAS2-like protein 1 1 0 RYS(0.921)GDS(0.071)DS(0.002)S(0.003)AS(0.001)S(0.001)AQSGPLGTR;RYS(1)GDSDSSASSAQSGPLGTR;RYS(1)GDSDSSASSAQSGPLGTR ;; 204.23 1.10E-17 52476000 2555.17 2324.26 2265.98 2076.71 2297.21 2463.07 2532.41 1712.45 2915.75 2190.9 TRUE FALSE FALSE 2352.925598 2525.158678 2349.959212 2068.117124 2269.817271 1952.201517 2603.462609 2234.568122 2595.89952 2267.033612 1.03788739 1.113860273 1.036578902 0.912256931 1.001227886 0.86112597 1.148400533 0.985679308 1.145064416 1 11.14659007 RYS(ph)PDELR ddPTM_HeLa_Curcumin_4h_R1 4 RYSPDELR 8 1 S5FZ81;Q8WUB8-3;Q8WUB8-2;Q8WUB8 S5FZ81 PHF10 PHD finger protein 10 1 0 RY(0.43)S(0.57)PDELR;RY(0.183)S(0.817)PDELR;RY(0.152)S(0.848)PDELR;RY(0.191)S(0.809)PDELR ;;; 97.163 0.0078334 61510000 4197.25 4164.08 4511.16 4505.34 4166.81 6025.56 3967.01 3578.13 4578.21 4384.16 TRUE FALSE FALSE 3865.033234 4524.00452 4678.347558 4486.698097 4117.123512 4775.790934 4078.313624 4669.085365 4075.991817 4536.509234 0.851983989 0.997243538 1.031265962 0.989019941 0.907553209 1.052745776 0.898998197 1.029224261 0.898486393 1 12.14736688 RYS(ph)SSGTPSSASPALSR ddPTM_HeLa_Curcumin_4h_R1 1 RYSSSGTPSSASPALSR 17 1 Q14934-2;Q14934-9;Q14934-3;Q14934-4;Q14934-5;Q14934-6;Q14934-7;Q14934;Q14934-8;Q14934-10;Q14934-18;Q14934-11;Q14934-12;Q14934-13;Q14934-14;Q14934-15;Q14934-16;Q14934-17 Q14934-2 NFATC4 "Nuclear factor of activated T-cells, cytoplasmic 4" 1 0 RYS(0.973)S(0.022)S(0.005)GTPSSASPALSR 85.473 0.010402 9281100 1083.3 697.25 963.07 829.25 992.37 1419.5 1586.8 917.62 1092.6 839.81 TRUE FALSE FALSE 997.5556619 757.5171831 998.7622214 825.8187832 980.5366359 1125.079699 1631.321337 1197.398114 972.7445136 868.993335 1.147943973 0.871718059 1.14933243 0.95031659 1.128359213 1.294693128 1.877254142 1.377914036 1.119392376 1 9.763201302 -5.018283801 3.44794718 1.057711786 1.628417895 0.7127588 0.144370449 0.080827766 2.009543151 0.018615768 0.05775668 9.59E-06 5.018283801 0.570706109 SRT(ph)GSESSQTGTSTTSS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 0 S(0.039)RT(0.961)GSESS(0.001)QT(0.001)GT(0.001)S(0.008)T(0.038)T(0.025)S(0.053)S(0.874)R 229.55 5.47E-23 143880000 7423.4 5903.7 5349 5981.1 6243.3 7124.7 4462 1389.6 6730 5861.9 TRUE FALSE FALSE 6835.830057 6413.989522 5547.238645 5956.351793 6168.852725 5646.956908 4587.191711 1813.282643 5991.735838 6065.600589 1.126983216 1.05743684 0.914540706 0.981988792 1.017022574 0.930980671 0.756263398 0.298945276 0.987822352 1 12.56643479 -4.26080481 1.296029481 1.042817742 4.90E-17 0.931715903 0.058256637 0.280473149 0.395841475 0.01035916 0.386813082 5.49E-05 4.26080481 -1.042817742 down RYWEEETVPTTAGAS(ph)PGPPR ddPTM_HeLa_Curcumin_4h_R1 1 RYWEEETVPTTAGASPGPPR 20 1 O15213 O15213 WDR46 WD repeat-containing protein 46 1 0 RYWEEETVPT(0.001)TAGAS(0.999)PGPPR 160.05 1.58E-05 11675000 825.11 627.24 617.97 776.84 607.73 1147.7 607.67 319.27 808.53 579.14 TRUE FALSE FALSE 759.8016728 681.4558307 640.8725118 773.6256419 600.4832167 909.6540828 624.7195847 416.6139533 719.8362818 599.2650719 1.267889134 1.137152593 1.069430778 1.290957338 1.002032731 1.517949444 1.042476216 0.695208135 1.201198461 1 9.227050479 -4.316717339 4.111148239 1.152848029 0.677965439 0.482371196 0.149818187 0.141567252 4.461928746 0.021392433 0.171311973 4.82E-05 4.316717339 -0.47488259 S(ph)AASPVVSSMPER ddPTM_HeLa_Curcumin_4h_R1 2 SAASPVVSSMPER 13 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 0 S(0.639)AAS(0.361)PVVSSMPER;S(0.63)AAS(0.361)PVVS(0.009)SMPER ; 190.57 7.94E-06 415350000 3937.9 3069.1 3438 3777.2 3886.1 3903 3793.1 1344.98 4032.8 3289.8 TRUE FALSE FALSE 3626.21106 3334.379328 3565.415304 3761.570947 3839.760796 3093.473804 3899.524177 1755.05821 3590.41193 3404.120305 1.065241747 0.979512776 1.047382285 1.105005291 1.12797447 0.908743971 1.145530659 0.515568797 1.054725335 1 11.73306631 -4.254189719 24.99179683 1.038090311 0.515568553 0.844602048 0.068420148 230.2359455 793674.1389 0.008741878 0.120323085 5.57E-05 4.254189719 -0.522521758 S(ph)AASQTADGSGCR ddPTM_HeLa_Curcumin_4h_R1 1 SAASQTADGSGCR 13 0 Q13905-2;Q13905;Q13905-4;Q13905-3 Q13905-2 RAPGEF1 Rap guanine nucleotide exchange factor 1 1 0 S(1)AASQTADGSGCR 108.36 0.0044006 5770200 3663.3 6502.1 5558.6 8186 3275.8 4352.2 3004.1 1748.1 4723.6 8409.6 TRUE FALSE FALSE 3373.34594 7064.112551 5764.606606 8152.128501 3236.738224 3449.504661 3088.386961 2281.087643 4205.432898 8701.832974 0.387659238 0.811795925 0.662458889 0.936828887 0.371960509 0.39641127 0.354912232 0.262138753 0.483281271 1 13.08710361 -13.52287875 0.230620504 3.689759063 0.439508992 0 0.254413349 35.88747887 0.462725408 43.99133908 0.1595611 3.00E-14 13.52287875 -3.250250071 S(ph)ADSENALSVQER ddPTM_HeLa_Curcumin_4h_R1 2 SADSENALSVQER 13 0 J3KRN4;J3QRB6;Q99759;Q99759-2 J3KRN4 MAP3K3 Mitogen-activated protein kinase kinase kinase 3 1 0 S(1)ADSENALSVQER;S(0.883)ADS(0.117)ENALSVQER ; 181.75 0.00012356 22459000 1211.17 776.12 1210.79 1244.35 1210.94 1382.34 939.85 706.38 1370.72 1074.41 TRUE FALSE FALSE 1115.304616 843.2043545 1255.662943 1239.201209 1196.500331 1095.627102 966.2196615 921.7520102 1220.355445 1111.745668 1.003201226 0.758450767 1.129451618 1.114644514 1.076235659 0.985501571 0.869101351 0.829103308 1.097693008 1 10.11861107 -4.735999628 3.537728625 1.006549274 0.838575581 0.313953491 0.100865603 0.211357445 5.427195236 0.013459316 0.055304436 1.84E-05 4.735999628 -0.167973692 YSVLNNDDYFADVSPLRATS(ph)PS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 YSVLNNDDYFADVSPLRATSPSK 23 1 Q1ED39;H3BMC9 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 2 0 YSVLNNDDY(0.001)FADVS(0.154)PLRAT(0.491)S(0.799)PS(0.555)K 66.467 0.0016005 30079000 4466.3 3808.1 3465.5 4229.5 3371.7 4984.4 3559.5 816.13 4606.3 3538.9 TRUE FALSE FALSE 4112.787642 4137.255195 3593.934479 4211.99945 3331.49468 3950.579254 3659.36999 1064.96428 4101.000414 3661.876512 1.123136629 1.129818327 0.981446116 1.15022979 0.909777997 1.078840109 0.999315509 0.290824739 1.119917726 1 11.83836743 -4.260648514 4.266805904 1.055736217 0.231677205 0.907936391 0.073192714 0.043801747 1.830647726 0.009960746 0.10951616 5.49E-05 4.260648514 -0.824059011 down NSPAT(ph)PPNTLNLR ddPTM_HeLa_Curcumin_4h_R1 1 NSPATPPNTLNLR 13 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2;D6RDY3;D6RB00;D6RB55 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 0 NS(0.349)PAT(0.627)PPNT(0.024)LNLR 139.64 0.0029265 12805000 2626.9 2484.4 2546 2280.5 2243.7 2874.1 2352.3 866.59 2643.9 2414.1 TRUE FALSE FALSE 2418.978093 2699.140466 2640.357 2271.063895 2216.945343 2277.979262 2418.299207 1130.809302 2353.870785 2497.989795 0.968369886 1.080525017 1.056992709 0.909156594 0.887491753 0.911924967 0.968098113 0.452687719 0.942306005 1 11.28655187 -4.260335056 5.962507617 0.979147928 0.437882653 0.869141392 0.060059923 0.035024139 5.831356183 0.008694731 0.076215909 5.49E-05 4.260335056 -0.541265275 down S(ph)AEDELAMR ddPTM_HeLa_Curcumin_4h_R1 1 SAEDELAMR 9 0 A3KFL1;A3KFL5;A3KFL2;Q13868-3;Q13868-2;Q13868 A3KFL1 EXOSC2 Exosome complex component RRP4 1 0 S(1)AEDELAMR 132.25 0.0035653 38475000 636.15 708.64 475.1 727.7 564.84 713 736.35 635.52 726.87 666.06 TRUE FALSE FALSE 585.7980562 769.891684 492.7076239 724.6889702 558.1046519 565.1157628 757.0099992 829.2871224 647.1341795 689.2055354 0.849961334 1.117071243 0.714892146 1.051484547 0.8097797 0.819952443 1.098380614 1.203250815 0.938956735 1 9.428790479 -4.58612783 5.222846933 0.920502396 1.18040466 0.416195629 0.115313517 0.124700487 6.510310892 0.015273177 0.061993031 2.59E-05 4.58612783 0.259902264 S(ph)AEEEAADLPTKPTK ddPTM_HeLa_Curcumin_4h_R1 1 SAEEEAADLPTKPTK 15 1 Q8WW12;Q8WW12-2 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 0 S(1)AEEEAADLPTKPTK 121.82 0.011336 8232000 1604.6 1076.9 1403.4 1275.3 1557.6 1468.3 1377.2 2940.4 1493.4 1480.9 TRUE FALSE FALSE 1477.594217 1169.982437 1455.411239 1270.023147 1539.026637 1163.758029 1415.840525 3836.914424 1329.577756 1532.361165 0.964259765 0.763516111 0.949783427 0.828801444 1.004349805 0.759454139 0.923960068 2.503923039 0.867666048 1 10.58154065 -4.261100893 24.99991368 0.939202914 2.503923507 0.962752322 0.09454842 3.688306843 272296.5689 0.01337642 0.104754242 5.48E-05 4.261100893 1.564720594 S(ph)AEEGELAESK ddPTM_HeLa_Curcumin_4h_R1 2 SAEEGELAESK 11 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 S(1)AEEGELAESK;S(1)AEEGELAESK ; 139.48 0.0014262 29125000 3385 2128.17 2443.51 2718.7 3321.5 2947.5 2386.4 2754.8 2888.5 2482.3 TRUE FALSE FALSE 3117.073678 2312.119532 2534.06863 2707.45074 3281.893282 2336.155275 2453.355961 3594.725838 2571.638777 2568.55974 1.213549223 0.900161867 0.986571809 1.054073494 1.277717326 0.909519541 0.955148492 1.39951031 1.00119874 1 11.32674391 -4.248385876 24.31845394 1.070358462 1.399510623 0.421600116 0.121913686 1266.383743 2359191.299 0.018102717 0.43705064 5.64E-05 4.248385876 0.329152161 RLAS(ph)TSDIEEKENR ddPTM_HeLa_Curcumin_4h_R1 1 RLASTSDIEEKENR 14 2 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 RLAS(0.964)T(0.028)S(0.008)DIEEKENR 101.54 0.0033438 65094000 1616.3 1255.3 1263.2 1363.8 1157.4 2441.3 2889.1 6272.5 1689.4 1840.9 TRUE FALSE FALSE 1488.368149 1363.802538 1310.015303 1358.156957 1143.598761 1934.946861 2970.16037 8184.956375 1504.077047 1904.871138 0.78134847 0.715955275 0.687718595 0.712991514 0.600354921 1.015788849 1.559244776 4.296855683 0.789595168 1 10.89547769 -4.195502756 2.055501002 0.835400483 5.6818657 0.98535948 0.128212999 0.089068675 0.351292847 0.02281094 0.850101444 6.38E-05 4.195502756 4.846465218 up S(ph)AEVDDGAAEKETLPEFGEGK ddPTM_HeLa_Curcumin_4h_R1 2 SAEVDDGAAEKETLPEFGEGK 21 1 H7C5W6;F5H619;Q86XA9-2;Q86XA9 H7C5W6 HEATR5A HEAT repeat-containing protein 5A 1 0 S(1)AEVDDGAAEKETLPEFGEGK;S(0.969)AEVDDGAAEKET(0.031)LPEFGEGK ; 109.39 1.92E-05 19083800 4316.9 4241.3 4548 4233.7 4279.1 5692.7 3952.9 3087.9 4500 4039.5 TRUE FALSE FALSE 3975.21281 4607.899073 4716.552881 4216.182071 4228.074527 4511.96985 4063.807735 4029.386495 4006.361258 4179.872324 0.951036898 1.102401872 1.128396399 1.008686808 1.01153198 1.079451596 0.972232504 0.963997506 0.958488908 1 12.02924316 -7.286570127 24.96010437 0.976878535 1.03847675 0.263421357 0.05190414 860.6262738 854780.2379 0.009456578 0.010815535 5.17E-08 7.286570127 0.061598215 S(ph)AGEEEDGPVLTDEQK ddPTM_HeLa_Curcumin_4h_R1 4 SAGEEEDGPVLTDEQK 16 0 H7BZV4;A0A0C4DG62;Q66PJ3-4;Q66PJ3-3;F5GYV5;F8WCT1;Q66PJ3-2;F5H7X4;Q66PJ3-7;Q66PJ3 H7BZV4;F5H7X4;Q66PJ3 ARL6IP4 ADP-ribosylation factor-like protein 6-interacting protein 4 1 0 S(1)AGEEEDGPVLTDEQK;S(1)AGEEEDGPVLTDEQK;S(1)AGEEEDGPVLTDEQK;S(1)AGEEEDGPVLTDEQK ;;; 383.36 2.95E-221 726818000 19132.6 15682.6 16677.2 16473.3 17609.9 18462.5 13478.4 12290.9 19219.8 16435.4 TRUE FALSE FALSE 17618.23452 17038.13406 17295.2717 16405.13785 17399.91344 14633.16938 13856.56763 16038.33883 17111.43603 17006.52893 1.035968868 1.001858412 1.016978349 0.964637635 1.023131382 0.860444212 0.814779294 0.943069506 1.006168637 1 14.05380109 -5.260461279 24.99594744 1.012514066 0.866965825 0.760000145 0.034413782 27.16604229 694230.0103 0.004688738 0.0112432 5.49E-06 5.260461279 -0.145548241 S(ph)AGEEVPVHPRS(ph)EAGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SAGEEVPVHPRSEAGSR 17 1 Q9NRF2-3;F5GXU7 Q9NRF2-3 SH2B1 SH2B adapter protein 1 3 0 S(1)AGEEVPVHPRS(1)EAGS(1)R 105.9 0.0070636 23849000 1062.5 1671.9 1147.2 1138.7 1045.4 1161.9 1143.7 821.21 1166.1 1768.7 TRUE FALSE FALSE 978.4020039 1816.411586 1189.716241 1133.988361 1032.934288 920.9088427 1175.789144 1071.593149 1038.181747 1830.162193 0.534598522 0.992486673 0.65006055 0.619610855 0.564394944 0.503184278 0.642450788 0.585518132 0.567262154 1 10.83775579 -13.52287872 0.281510746 3.924516114 0.594482161 0 0.187425263 27.01525109 0.364629361 44.45340906 0.061833203 3.00E-14 13.52287872 -3.330033953 S(ph)ALEDKERDEDDEDGDGDGDGATGK ddPTM_HeLa_Curcumin_4h_R1 1 SALEDKERDEDDEDGDGDGDGATGK 25 2 G3V1U3;F8VQZ7;P50579-3;P50579 G3V1U3 METAP2 Methionine aminopeptidase 2 1 0 S(1)ALEDKERDEDDEDGDGDGDGATGK 77.488 0.00017401 8649800 1748.6 1422.3 1436.6 1546 1360.6 2286.5 2155.9 461.78 1959 1632.5 TRUE FALSE FALSE 1610.196465 1545.237274 1489.84166 1539.603062 1344.375734 1812.254126 2216.388752 602.5745962 1744.102601 1689.229253 0.953213699 0.91475877 0.881965344 0.911423395 0.795851558 1.072828997 1.312071021 0.3567157 1.032484251 1 10.72214942 -4.239712702 24.68105826 0.973356194 0.356714943 0.668104606 0.132802059 2228.661568 2531669.685 0.017652864 1.143372185 5.76E-05 4.239712702 -0.616641252 S(ph)AMPFTASPASSTTAR ddPTM_HeLa_Curcumin_4h_R1 1 SAMPFTASPASSTTAR 16 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 0 S(0.866)AMPFT(0.043)AS(0.07)PAS(0.002)S(0.015)T(0.004)TAR 111.52 0.0017636 110970000 3086.1 2830.3 2515.7 2799.9 2867.9 4214.2 3774.7 1579.2 3082.1 2490.8 TRUE FALSE FALSE 2841.831929 3074.93852 2608.934055 2788.314756 2833.702166 3340.127416 3880.607923 2060.69081 2744.001341 2577.355115 1.102615589 1.1930597 1.01225246 1.081851212 1.099461285 1.295951573 1.505655119 0.799537013 1.064657845 1 11.33167561 -5.4179423 4.943384212 1.061683423 1.229781112 0.085925932 0.170699088 0.295115865 11.15923898 0.022646569 0.051539472 3.82E-06 5.4179423 0.168097689 S(ph)APAS(ph)PT(ph)HPGLMSPR ddPTM_HeLa_Curcumin_4h_R1 1 SAPASPTHPGLMSPR 15 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 3 0 S(1)APAS(0.966)PT(0.691)HPGLMS(0.342)PR 77.24 0.012337 19350000 2064.3 1685.8 1541.2 2317.4 2245.9 2273.3 1609.1 1742.9 2139.2 2047.3 TRUE FALSE FALSE 1900.908477 1831.51304 1598.318228 2307.811213 2219.119109 1801.791955 1654.247015 2274.302187 1904.535112 2118.443523 0.897313738 0.864555992 0.75447762 1.089390011 1.047523375 0.850526311 0.780878507 1.073572254 0.899025672 1 11.04878895 -9.273883663 1.080628383 0.998468894 0.914902112 0 0.115412369 1.127240863 2.421268541 0.068274917 0.019899763 5.32E-10 9.273883663 -0.083566782 S(ph)APAS(ph)PTHPGLMS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 SAPASPTHPGLMSPR 15 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 3 0 S(1)APAS(0.975)PT(0.206)HPGLMS(0.818)PR;S(1)APAS(0.983)PT(0.025)HPGLMS(0.992)PR;S(0.999)APAS(0.932)PT(0.374)HPGLMS(0.694)PR ;; 120.08 0.0022983 47567000 8291.2 6423 7035.2 7671.3 7919.1 8647.6 6623.7 5868.4 8260.4 7540 TRUE FALSE FALSE 7634.942771 6978.1755 7295.930701 7639.558193 7824.669905 6853.990281 6809.543195 7657.648145 7354.254787 7802.014439 0.978586086 0.894406894 0.935134222 0.979177654 1.002903797 0.878489823 0.87279295 0.98149628 0.942609738 1 12.92963095 -7.559267295 0.387561905 1.006437239 0.922960969 0 0.047349584 1.08015608 0.456983954 0.032173889 0.028254477 2.76E-08 7.559267295 -0.08347627 S(ph)APAS(ph)PTHPGLMSPR ddPTM_HeLa_Curcumin_4h_R1 1 SAPASPTHPGLMSPR 15 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 2 0 S(0.982)APAS(0.769)PT(0.247)HPGLMS(0.002)PR 84.62 0.014536 10196000 1464.3 1247.2 1369.8 1449.7 1403.5 2568.9 2008.6 1588.9 1805.1 1783.3 TRUE FALSE FALSE 1348.39911 1355.002411 1420.565993 1443.701526 1386.764179 2036.081183 2064.95591 2073.348296 1607.085046 1845.269542 0.730732871 0.734311373 0.769841999 0.782379751 0.751523909 1.103405836 1.119053809 1.123601863 0.87092157 1 10.84961585 -5.247559905 23.13006672 0.837574925 1.115723954 0.749769214 0.080521063 178.2011591 296968.7743 0.016929213 0.042858244 5.66E-06 5.247559905 0.278149029 S(ph)APASPT(ph)HPGLMSPR ddPTM_HeLa_Curcumin_4h_R1 1 SAPASPTHPGLMSPR 15 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 2 0 S(1)APAS(0.022)PT(0.977)HPGLMS(0.002)PR 115.26 0.0075648 185540000 1134.5 1107.8 1052.9 1112.6 1294.6 1856.9 1257.1 1128.8 1545.4 1565.3 TRUE FALSE FALSE 1044.703128 1203.553296 1091.9214 1107.996356 1279.162741 1471.758008 1292.370843 1472.965924 1375.873486 1619.694058 0.645000284 0.743074465 0.674152871 0.684077558 0.789755778 0.908664202 0.797910467 0.909409969 0.849465045 1 10.66150562 -2.861614313 14.75435116 0.808262131 43.68984334 0 0.111145471 0 0 0.019763968 0 0.001375263 2.861614313 42.88158121 S(ph)APS(ph)SPAPR ddPTM_HeLa_Curcumin_4h_R1 1 SAPSSPAPR 9 0 E9PAK5;O75064 E9PAK5 DENND4B DENN domain-containing protein 4B 2 0 S(1)APS(0.614)S(0.386)PAPR 119.53 0.015174 6645900 3601.6 3162.4 3251.1 3036.2 3336.7 3766 2921.3 2867 3251 3112.9 TRUE FALSE FALSE 3316.52956 3435.743765 3371.588626 3023.637009 3296.912032 2984.889148 3003.263816 3741.135102 2894.373434 3221.073043 1.029635005 1.066645717 1.046728398 0.938704888 1.023544635 0.926675399 0.932379917 1.161456152 0.898574293 1 11.65332566 -6.306723354 24.99936027 1.021368136 0.990604457 0 0.076643603 1126.945931 622137.4098 0.009664492 0.014762767 4.93E-07 6.306723354 -0.030763679 S(ph)APS(ph)SPTLDCEK ddPTM_HeLa_Curcumin_4h_R1 1 SAPSSPTLDCEK 12 0 J3QSD2;J3QRZ1;A6NIZ0;Q9GZM8-3;Q9GZM8;Q9GZM8-2 J3QSD2 NDEL1 Nuclear distribution protein nudE-like 1 2 0 S(1)APS(0.593)S(0.368)PT(0.039)LDCEK 155.39 0.00081698 28887000 3731.4 3212.8 3123.5 3129.1 3335.2 4228.6 4025.6 4350.1 3596.8 2869.4 TRUE FALSE FALSE 3436.055753 3490.500116 3239.259658 3116.152613 3295.429918 3351.540694 4138.547502 5676.425465 3202.240039 2969.111436 1.15726736 1.175604281 1.090986218 1.04952363 1.109904424 1.128802595 1.393867354 1.911826345 1.07851797 1 11.53581553 -4.256375083 1.591016622 1.084221839 2.234386261 0.964342247 0.048078074 0.181918677 0.422148671 0.009754784 0.324860933 5.54E-05 4.256375083 1.150164422 S(ph)APSS(ph)PTLDCEK ddPTM_HeLa_Curcumin_4h_R1 1 SAPSSPTLDCEK 12 0 J3QSD2;J3QRZ1;A6NIZ0;Q9GZM8-3;Q9GZM8;Q9GZM8-2 J3QSD2 NDEL1 Nuclear distribution protein nudE-like 1 2 0 S(1)APS(0.213)S(0.776)PT(0.01)LDCEK 103.97 0.017593 28449000 4441.2 4258.2 4520.9 4432.7 4728 6135.1 5520.1 6459.2 4861.2 4398.2 TRUE FALSE FALSE 4089.674334 4626.259834 4688.448531 4414.358662 4671.621688 4862.611103 5674.979149 8428.580346 4327.938522 4551.037123 0.898624692 1.016528696 1.030193427 0.969967623 1.026496063 1.068462193 1.246963933 1.852013095 0.950978514 1 12.15197964 -2.746021634 0.8845401 0.962556166 13.42377353 0.978569234 0.03858394 3.098942805 0.204415238 0.007728122 66.64408369 0.001794644 2.746021634 12.46121737 S(ph)APSTGGVK ddPTM_HeLa_Curcumin_4h_R1 1 SAPSTGGVK 9 0 K7EMV3;K7EP01;A0A590UJJ6;B4DEB1;K7EK07;K7ES00;P84243 K7EMV3 H3F3B;H3F3A Histone H3;Histone H3.3 1 0 S(1)APSTGGVK 104.22 0.011016 10552000 1875.9 1835.1 1768.8 2006.4 2328 4331.2 2880.8 902.87 2978.3 2438.8 TRUE FALSE FALSE 1727.420536 1993.717867 1834.353284 1998.098048 2300.24012 3432.860297 2961.627495 1178.150907 2651.587941 2523.548118 0.684520546 0.790045513 0.726894514 0.791781236 0.911510307 1.360330826 1.173596601 0.466862866 1.050738015 1 11.30123788 -5.515324976 24.49375334 0.829355288 1.037317369 0.07631137 0.236831242 409.9112467 1329170.024 0.033880267 0.070212863 3.05E-06 5.515324976 0.207962081 S(ph)APT(ph)SPTATNISSK ddPTM_HeLa_Curcumin_4h_R1 1 SAPTSPTATNISSK 14 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 2 0 S(1)APT(0.965)S(0.035)PT(0.001)ATNISSK 196.18 1.33E-05 31391000 3388.1 3194.5 3296.5 3729.1 3246.2 3818.9 2827.3 1707.2 3264 3668.1 TRUE FALSE FALSE 3119.92831 3470.618346 3418.67119 3713.669972 3207.491185 3026.817092 2906.626429 2227.717421 2905.947366 3795.566202 0.821992858 0.914387515 0.900701241 0.978423185 0.845062637 0.797461283 0.765795213 0.586926246 0.765616304 1 11.8900994 -3.581999169 0.646090955 0.918712586 2.06E-12 0.633313556 0.069352462 2.908341623 0.450774072 0.012165932 2.418822464 0.000261819 3.581999169 -0.918712586 S(ph)APTS(ph)PTATNISSK ddPTM_HeLa_Curcumin_4h_R1 1 SAPTSPTATNISSK 14 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 2 0 S(1)APT(0.229)S(0.764)PT(0.006)AT(0.002)NISSK 153.41 0.001036 55826000 6320 5533 6429.3 6552.5 6843.4 7327.8 5858.1 3607.2 6084.2 6104 TRUE FALSE FALSE 5819.765331 6011.247865 6667.575514 6525.387491 6761.796925 5807.931679 6022.46252 4707.018674 5416.778482 6316.113546 0.921415565 0.951732077 1.05564529 1.033133341 1.070562914 0.919541999 0.95350764 0.745239718 0.857612588 1 12.62482139 -4.0162086 1.767411124 0.978755637 0.524842009 0.542767004 0.063187682 1.052136676 1.893377501 0.008276531 0.980008384 9.63E-05 4.0162086 -0.453913627 SLIGS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 1 SLIGSPGR 8 0 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 SLIGS(1)PGR 94.409 0.018325 21115000 4336.1 3739.9 3692.9 3573.4 3723.2 4680.2 3630.8 971.72 4374.8 3625.3 TRUE FALSE FALSE 3992.89311 4063.160291 3829.762123 3558.614218 3678.803272 3709.473763 3732.670476 1267.992955 3894.895385 3751.278905 1.064408489 1.083140015 1.020921723 0.948640266 0.980679753 0.988855763 0.995039444 0.338016177 1.038284671 1 11.87316682 -4.260126114 5.14339576 1.021631257 0.306533311 0.966007635 0.03800749 0.023485051 2.039795415 0.006229342 0.05927009 5.49E-05 4.260126114 -0.715097946 down S(ph)AQWLDQEEAPK ddPTM_HeLa_Curcumin_4h_R1 2 SAQWLDQEEAPK 12 0 Q53H47-3;Q53H47 Q53H47-3 SETMAR Histone-lysine N-methyltransferase SETMAR;Histone-lysine N-methyltransferase;Transposon Hsmar1 transposase 1 0 S(1)AQWLDQEEAPK;S(1)AQWLDQEEAPK ; 241.39 2.25E-26 25472300 4883.7 3700 4099.1 3975.1 4372 5081.7 4673.9 5799.1 4764.4 4259.2 TRUE FALSE FALSE 4497.149992 4019.811513 4251.016252 3958.652089 4319.866755 4027.698137 4805.037055 7567.218894 4241.75724 4407.206883 1.020408188 0.912099572 0.964560177 0.898222433 0.980182431 0.913889056 1.090268096 1.717010137 0.962459297 1 12.10564891 -4.268117744 3.400549819 0.984564279 1.806017504 0.961200578 0.0453536 0.044922194 0.871414585 0.007071101 0.09452963 5.39E-05 4.268117744 0.821453225 S(ph)ARS(ph)VRAQRHTDMPK ddPTM_HeLa_Curcumin_4h_R1 1 SARSVRAQRHTDMPK 15 3 P05019-3;P05019-2;P05019-4;P05019 P05019-3 IGF1 Insulin-like growth factor I 2 0 S(0.992)ARS(0.994)VRAQRHT(0.014)DMPK 56.407 0.019826 10551000 1917.9 1850.8 2203.1 2202.7 1825.4 1910.4 1429.6 2028.8 2005.2 2389.2 TRUE FALSE FALSE 1766.096191 2010.774905 2284.748824 2193.585811 1803.633297 1514.161505 1469.710728 2647.371781 1785.234577 2472.224522 0.714375323 0.813346396 0.924167204 0.887292312 0.729558857 0.612469253 0.59448918 1.070846016 0.722116685 1 11.27159406 -9.419106395 1.019751654 1.006685078 0.780462195 0 0.161180662 0.640666497 1.133819925 0.10988937 0.024627189 3.81E-10 9.419106395 -0.226222883 S(ph)AS(ph)AS(ph)PLTPCSVTR ddPTM_HeLa_Curcumin_4h_R1 1 SASASPLTPCSVTR 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 3 0 S(1)AS(0.998)AS(0.763)PLT(0.236)PCS(0.002)VT(0.001)R 93.228 0.0022828 0 1700.2 1594.7 1692.1 1452.1 1519.6 2390 1890.2 1063.7 1881.4 1020.6 TRUE FALSE FALSE 1565.627376 1732.538762 1754.810715 1446.091595 1501.479762 1894.287059 1943.233925 1388.017233 1675.015127 1056.065774 1.482509342 1.640559523 1.661649073 1.36931963 1.421767279 1.793720719 1.84006903 1.314328395 1.586089776 1 10.04448398 -8.913389825 0.498430722 0.920827712 1.603886982 0 0.245118189 0.622970117 0.257076969 0.202448843 0.047907898 1.22E-09 8.913389825 0.683059271 NYPS(ph)QEELIK ddPTM_HeLa_Curcumin_4h_R1 2 NYPSQEELIK 10 0 P38398-8;P38398-4;P38398;P38398-7;K7EPC7;H0Y8B8;B7ZA85;E7EUM2;A0A2R8Y7V5;P38398-6;P38398-5;P38398-3 P38398-8 BRCA1 Breast cancer type 1 susceptibility protein 1 0 NYPS(1)QEELIK;NYPS(1)QEELIK ; 139.48 0.0015792 76050000 10101.1 8015 9180.6 9770.6 10209.7 10860.5 8561.4 1944.95 9933.4 8173.7 TRUE FALSE FALSE 9301.587276 8707.780886 9520.841112 9730.171846 10087.956 8607.909877 8801.609842 2537.956302 8843.730872 8457.735467 1.099772784 1.02956411 1.125696252 1.150446462 1.192749056 1.017755865 1.040657972 0.300075157 1.045638151 1 13.04605572 -4.2601017 5.279550923 1.067482975 0.267485873 0.938038865 0.059966458 0.03113899 3.01909041 0.009602511 0.089907215 5.49E-05 4.2601017 -0.799997102 down S(ph)AS(ph)PHDVDLCLVSPCEFEHR ddPTM_HeLa_Curcumin_4h_R1 1 SASPHDVDLCLVSPCEFEHR 20 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 2 0 S(1)AS(1)PHDVDLCLVSPCEFEHR 100.14 0.0011805 4249800 1627.5 2693.4 1934.7 1482.3 1640.4 1727.2 1318.8 919.77 1768.5 2245 TRUE FALSE FALSE 1498.681658 2926.205494 2006.401684 1476.166635 1620.839301 1368.95925 1355.801979 1200.203639 1574.499975 2323.013583 0.645145456 1.259659227 0.863706394 0.635453295 0.697731306 0.589303162 0.583639282 0.516658038 0.67778337 1 11.18178187 -6.233262522 4.788824176 0.869461712 0.605048297 0.424025026 0.165421806 0.187792786 11.35071775 0.028260898 0.046521911 5.84E-07 6.233262522 -0.264413415 S(ph)AS(ph)PPPATSSSSSSR ddPTM_HeLa_Curcumin_4h_R1 2 SASPPPATSSSSSSR 15 0 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 2 0 S(0.999)AS(0.655)PPPAT(0.236)S(0.061)S(0.016)S(0.012)S(0.01)S(0.007)S(0.005)R;S(1)AS(0.976)PPPAT(0.017)S(0.004)S(0.001)S(0.001)S(0.001)SSR ; 103.66 0.0069204 94658000 13579.3 17291.6 15452.6 13945 11084 12683.3 11315.7 8806 13211.5 16969.8 TRUE FALSE FALSE 12504.48408 18786.20885 16025.28695 13887.29928 10951.83054 10052.64061 11633.18809 11490.90886 11762.2315 17559.49929 0.712120766 1.069860168 0.912627786 0.79087103 0.623698339 0.572490163 0.662501128 0.654398436 0.669850052 1 14.09996409 -5.903955852 3.273900559 0.882035828 0.625921138 0.505952335 0.113817225 0.162313095 3.471396385 0.018621465 0.03540755 1.25E-06 5.903955852 -0.256114691 S(ph)AS(ph)PYPSHSLS(ph)SPQR ddPTM_HeLa_Curcumin_4h_R1 1 SASPYPSHSLSSPQR 15 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 3 0 S(0.999)AS(0.972)PY(0.029)PS(0.003)HS(0.11)LS(0.762)S(0.125)PQR 120.99 0.0031915 49849000 5193.7 4305.4 4626.3 5069.4 5397.7 6201.7 4146.6 3720.4 5835.3 4592.6 TRUE FALSE FALSE 4782.613165 4677.539592 4797.754748 5048.424166 5333.335953 4915.397512 4262.942436 4854.732833 5195.182189 4752.192508 1.006401394 0.984290848 1.009587625 1.062335787 1.122289542 1.034343096 0.897047506 1.021577477 1.093217958 1 12.21437756 -6.509153934 24.02157609 1.00147562 1.026919189 0 0.060032121 1112.75572 1947576.193 0.008636555 0.012841132 3.10E-07 6.509153934 0.025443569 S(ph)AS(ph)PYPSHSLSS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 2 SASPYPSHSLSSPQR 15 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 3 0 S(0.981)AS(0.99)PY(0.018)PS(0.01)HS(0.026)LS(0.131)S(0.843)PQR;S(0.996)AS(0.952)PY(0.049)PS(0.107)HS(0.173)LS(0.12)S(0.604)PQR ; 92.236 0.0031562 50380000 5096.5 4441.9 4729.3 4767.8 4742.3 6051 4623.1 3957.1 5554.8 4655.5 TRUE FALSE FALSE 4693.106647 4825.838043 4904.572018 4748.072107 4685.75117 4795.954391 4752.811744 5163.601574 4945.452337 4817.278278 0.974223696 1.001776888 1.018120967 0.985633761 0.972696801 0.995573457 0.986617644 1.071891901 1.026607153 1 12.23400255 -4.260060715 24.84339637 0.989851448 1.07189193 0.621528648 0.017305644 41.83662193 753806.1502 0.002011827 0.017061315 5.49E-05 4.260060715 0.082040482 S(ph)ASADNLTLPR ddPTM_HeLa_Curcumin_4h_R1 1 SASADNLTLPR 11 0 Q8ND76-3;Q8ND76-2;Q8ND76 Q8ND76-3 CCNY Cyclin-Y 1 0 S(0.794)AS(0.206)ADNLTLPR 96.707 0.0131 34090000 1454.8 1302.1 1593.4 2035.6 1831.8 2563.2 1454.7 742.73 2558.1 1954.5 TRUE FALSE FALSE 1339.651045 1414.647722 1652.452806 2027.177227 1809.956981 2031.563427 1495.514967 969.1849579 2277.48283 2022.41873 0.662400434 0.6994831 0.817067594 1.002352874 0.894946707 1.004521664 0.739468511 0.479220719 1.126118344 1 10.98186601 -9.569319211 1.373283248 0.999027727 0.783583087 0.310071876 0.156704177 0.567841201 1.93338185 0.111397255 0.026646135 2.70E-10 9.569319211 -0.21544464 AGEPDGES(ph)LDEQPSSSSSK ddPTM_HeLa_Curcumin_4h_R1 2 AGEPDGESLDEQPSSSSSK 19 0 Q9H3Q1;J3KRZ9 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 0 AGEPDGES(1)LDEQPSSSSSK;AGEPDGES(1)LDEQPSSSSSK ; 207.16 1.38E-13 158260000 9630.6 9100 9126.7 9197.9 10977.6 11215.3 8178.1 1974.35 9409.7 7718.5 TRUE FALSE FALSE 8868.327848 9886.563451 9464.943531 9159.841527 10846.69929 8889.120358 8407.555476 2576.320226 8377.479452 7986.7173 1.110384594 1.237875723 1.185085583 1.146884406 1.358092303 1.11298798 1.052692259 0.322575613 1.048926503 1 12.96338693 -4.260096598 4.312248933 1.107275717 0.263164476 0.852756943 0.101273059 0.070491786 3.061725212 0.016637413 0.182102724 5.49E-05 4.260096598 -0.844111241 down S(ph)ASASPLT(ph)PCSVTR ddPTM_HeLa_Curcumin_4h_R1 1 SASASPLTPCSVTR 14 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 0 S(0.907)AS(0.049)AS(0.044)PLT(0.97)PCS(0.025)VT(0.004)R 119.77 0.0081417 11309000 2071.3 1746.6 1801 1878.7 2177.8 3194.9 2773.6 1462.4 2407.4 1325.1 TRUE FALSE FALSE 1907.354419 1897.568321 1867.746644 1870.926437 2151.831157 2532.241726 2851.419751 1908.279028 2143.314243 1371.147126 1.391064739 1.383927578 1.362178142 1.364497216 1.569365618 1.846805261 2.079587009 1.391739071 1.563154093 1 10.42116767 -6.009053449 0.11344742 0.56538233 2.517048277 0.171316743 0.25573097 8.625480448 0.356521606 2.055384803 4.012714771 9.79E-07 6.009053449 1.951665948 S(ph)ASDLSEDLFK ddPTM_HeLa_Curcumin_4h_R1 1 SASDLSEDLFK 11 0 Q92541 Q92541 RTF1 RNA polymerase-associated protein RTF1 homolog 1 0 S(0.999)ASDLSEDLFK 144.57 0.00016792 0 1911.4 1505.4 1644.3 1157.2 1953.6 2362 2464.8 1671.2 1770.9 1268.9 TRUE FALSE FALSE 1760.110673 1635.520068 1705.239204 1152.411813 1930.304596 1872.094575 2533.955654 2180.741187 1576.636701 1312.994181 1.340531968 1.245641521 1.29874087 0.877697579 1.470154723 1.425820923 1.929906234 1.660891738 1.200794888 1 10.35864481 -1.000000002 0.286179549 1.107150794 7.075249938 0.5588208 0.191855578 25.99577869 0.331949706 0.083219653 79.22389259 0.1 1.000000002 5.968099145 T(ph)PSIQPSLLPHAAPFAK ddPTM_HeLa_Curcumin_4h_R1 1 TPSIQPSLLPHAAPFAK 17 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3;A0A0A0MSW3;H0YF36 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 0 T(0.5)PS(0.5)IQPSLLPHAAPFAK 107.02 0.0013048 30185000 1870.5 1379.9 1577.6 1595.3 2422.2 3513 2993.4 9088.3 2208.7 2112.3 TRUE FALSE FALSE 1722.447951 1499.172407 1636.067244 1588.699071 2393.316847 2784.3642 3077.386748 11859.28083 1966.411136 2185.702268 0.788052415 0.685899644 0.748531613 0.726859781 1.094987585 1.273899122 1.407962463 5.425844594 0.899670172 1 11.09388118 -4.195090245 2.523714075 0.892292868 6.909176787 0.98217393 0.181542305 0.066125058 0.447546666 0.028158918 0.907332649 6.38E-05 4.195090245 6.016883919 up S(ph)ASEPSLNR ddPTM_HeLa_Curcumin_4h_R1 1 SASEPSLNR 9 0 H7C560;A0A2U3TZI2;A0A2R8Y8E0;P15056 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 0 S(0.517)AS(0.332)EPS(0.151)LNR 95.483 0.015778 147300000 1569.9 1611.8 1403.3 1372 1583.2 1672.2 1081.3 1229.4 1499.2 1564.1 TRUE FALSE FALSE 1445.640758 1751.11681 1455.307532 1366.323028 1564.321374 1325.36687 1111.638368 1604.238401 1334.741511 1618.452359 0.893224166 1.081969945 0.899197017 0.844215784 0.96655386 0.818910031 0.686852697 0.991217562 0.824702379 1 10.66039918 -5.826903814 1.05080537 0.957069896 0.827976221 0.114188494 0.101670474 0.573843118 1.23432653 0.015438104 0.044138485 1.49E-06 5.826903814 -0.129093675 S(ph)ASPCIADK ddPTM_HeLa_Curcumin_4h_R1 1 SASPCIADK 9 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 0 S(0.5)AS(0.5)PCIADK 118.23 0.0066928 38674000 3264.7 2620.7 2781.4 2857.4 3030.9 4270 3542.3 2036 3083 2367.5 TRUE FALSE FALSE 3006.29555 2847.22163 2884.481131 2845.576836 2994.758497 3384.353867 3641.687404 2656.767027 2744.802613 2449.770449 1.227174388 1.162240173 1.177449557 1.161568765 1.222464945 1.381498364 1.486542303 1.084496316 1.120432575 1 11.25843086 -13.52287873 0.124182756 0.130270742 1.377938915 0.301624225 0.111906709 57.00603858 0.507465822 12.33425393 0.4519365 3.00E-14 13.52287873 1.247668174 S(ph)ASPDDDLGSSNWEAADLGNEERK ddPTM_HeLa_Curcumin_4h_R1 1 SASPDDDLGSSNWEAADLGNEERK 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 0 S(0.428)AS(0.366)PDDDLGS(0.103)S(0.103)NWEAADLGNEERK 61.022 0.0043841 0 490.38 625.61 362.18 451.6 553.76 395.39 382.36 558.89 463.1 750.97 TRUE FALSE FALSE 451.5659056 679.6849407 375.6027094 449.7313989 547.1567737 313.381657 393.0879925 729.2929882 412.2990886 777.0661516 0.581116427 0.874680926 0.483360018 0.578755616 0.704131524 0.403288261 0.505861685 0.938521111 0.530584285 1 9.60189361 -9.494570431 0.563676815 1.098434024 0.611160817 0 0.217320795 1.107242755 0.430959257 0.298029574 0.03587018 3.20E-10 9.494570431 -0.487273207 S(ph)ASPHDVDLCLVSPCEFEHR ddPTM_HeLa_Curcumin_4h_R1 1 SASPHDVDLCLVSPCEFEHR 20 0 Q66K74-2;Q66K74 Q66K74-2 MAP1S Microtubule-associated protein 1S;MAP1S heavy chain;MAP1S light chain 1 0 S(0.842)AS(0.158)PHDVDLCLVSPCEFEHR 99.371 0.00021372 11220000 4669.7 4123 3612.7 3746.3 4992.2 6139.1 3528.5 2217.7 5105.6 3768.5 TRUE FALSE FALSE 4300.088318 4479.373748 3746.58984 3730.798803 4932.671276 4865.781458 3627.500214 2893.866521 4545.528454 3899.455094 1.102740822 1.148717869 0.960798304 0.956748754 1.264964247 1.247810615 0.930258235 0.742120745 1.165682985 1 11.92905682 -4.485692046 4.723334878 1.070744223 0.771815319 0.511117133 0.108204495 0.135094803 6.986456724 0.015307227 0.084569358 3.27E-05 4.485692046 -0.298928903 S(ph)ASPPPATSSSSSSR ddPTM_HeLa_Curcumin_4h_R1 1 SASPPPATSSSSSSR 15 0 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 1 0 S(0.992)AS(0.007)PPPATSSSSSSR 77.776 0.018044 1561200 622.55 698.92 490.07 649.18 585.44 548.18 574.21 630.8 946.11 554.54 TRUE FALSE FALSE 573.2745106 759.3315305 508.2324253 646.4938652 578.4590104 434.4812887 590.3207872 823.1280162 842.3241001 573.8102237 0.999066393 1.323314746 0.88571518 1.126668432 1.00810161 0.757186385 1.028773561 1.434495208 1.467948923 1 9.164429863 -4.265327003 6.04413192 1.007469414 1.444992907 0.18428525 0.200922511 0.081004721 14.53849699 0.017874412 0.14555212 5.43E-05 4.265327003 0.437523493 S(ph)ASTDLGTADVVLGR ddPTM_HeLa_Curcumin_4h_R1 1 SASTDLGTADVVLGR 15 0 H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5-3;Q9Y2K5-2;Q9Y2K5 H7C0E9 R3HDM2 R3H domain-containing protein 2 1 0 S(0.806)AS(0.191)T(0.004)DLGTADVVLGR 178.68 6.79E-05 3562200 1057 858.8 1009.7 978.58 931.06 2288.3 2255.5 808.05 852.02 861.8 TRUE FALSE FALSE 973.3373347 933.0308453 1047.12037 974.5308952 919.9577176 1813.680786 2318.78326 1054.420725 758.5555376 891.7474859 1.091494341 1.046294899 1.174234171 1.092832793 1.031634776 2.033850181 2.600268906 1.182420743 0.85063939 1 9.800491433 -5.261545546 24.99997601 1.05760095 2.004988891 0.605138511 0.330870977 3.977612784 936788.5478 0.040796551 0.097041503 5.48E-06 5.261545546 0.947387941 S(ph)ASWGSADQLK ddPTM_HeLa_Curcumin_4h_R1 1 SASWGSADQLK 11 0 Q86VQ1;H7C0Q2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 0 S(0.958)AS(0.041)WGSADQLK 174.21 0.00021557 31981000 3707.9 3320.3 3895.8 3441.7 4062.2 4259 3230.3 1587 3536.2 3134.8 TRUE FALSE FALSE 3414.415802 3607.291937 4040.181775 3427.459157 4013.760918 3375.635391 3320.933524 2070.868994 3148.287707 3243.734067 1.052618905 1.112080048 1.245534218 1.056639998 1.23738902 1.040663421 1.023799564 0.638421323 0.970575159 1 11.66343983 -4.249260131 3.413194816 1.065109321 0.57773758 0.691933056 0.088586692 0.15665241 2.98691246 0.012971226 0.200672515 5.63E-05 4.249260131 -0.487371741 S(ph)ATFPNAGPR ddPTM_HeLa_Curcumin_4h_R1 1 SATFPNAGPR 10 0 Q86X27;Q86X27-3 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 0 S(0.945)AT(0.055)FPNAGPR 131.12 0.0027619 26768000 1942.9 1795.5 1724 1824.6 1769.4 1324.1 1327.4 1519.4 1945.9 1743 TRUE FALSE FALSE 1789.117415 1950.695019 1787.892957 1817.050289 1748.301061 1049.466734 1364.643271 1982.658066 1732.439638 1803.56912 0.991987163 1.08157486 0.991308255 1.007474717 0.969356284 0.58188329 0.756634861 1.099296968 0.960561821 1 10.816639 -5.494573653 24.66695214 1.002931144 0.801776608 0.336762344 0.121315005 467.5504761 407454.3191 0.01616839 0.036078463 3.20E-06 5.494573653 -0.201154536 S(ph)AVDLSCSR ddPTM_HeLa_Curcumin_4h_R1 1 SAVDLSCSR 9 0 Q9Y446;Q9Y446-2;E9PK71;E9PQ15 Q9Y446 PKP3 Plakophilin-3 1 0 S(1)AVDLSCSR 115.29 0.0074559 30957000 767.27 740.64 1040 958.98 920.21 1674.6 1306.7 327.65 1091.7 665.06 TRUE FALSE FALSE 706.5397699 804.6576214 1078.543315 955.0119949 909.2370968 1327.269083 1343.362485 427.5489767 971.9432413 688.1707855 1.026692479 1.169270243 1.567261118 1.387754341 1.321237571 1.928691411 1.952077178 0.621283242 1.412357603 1 9.426622837 -6.922029841 3.309688507 1.014206668 1.49699871 0.110068567 0.370220875 0.221896415 4.911408093 0.054538089 0.072433535 1.20E-07 6.922029841 0.482792042 S(ph)AVEAQNEVTENPK ddPTM_HeLa_Curcumin_4h_R1 1 SAVEAQNEVTENPK 14 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 0 S(1)AVEAQNEVTENPK 249.54 1.62E-30 8653300 1500.2 1305.3 1336.5 1357.8 1384.5 1772.4 1518.8 958.2 1511.9 1341 TRUE FALSE FALSE 1381.457587 1418.124316 1386.031866 1352.181783 1367.990742 1404.784261 1561.41344 1250.350769 1346.048353 1387.59965 0.995573606 1.021998179 0.998870146 0.974475443 0.985868468 1.012384416 1.125262204 0.901088991 0.970055269 1 10.43837567 -5.000373456 24.99999984 0.997362188 1.0270875 0.011645008 0.052473647 30.56940812 2047029.821 0.006256779 0.018469668 9.99E-06 5.000373456 0.029725312 S(ph)HEAEVLK ddPTM_HeLa_Curcumin_4h_R1 3 SHEAEVLK 8 0 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 1 0 S(1)HEAEVLK;S(1)HEAEVLK;S(1)HEAEVLK ;; 133.75 0.002111 175167300 18109.1 14176.5 14578 17121.3 17616.2 20181.6 13508.4 4962.8 17257.3 14440.3 TRUE FALSE FALSE 16675.74563 15401.85349 15118.2735 17050.4566 17406.13832 15995.70867 13887.40935 6475.934874 15364.21737 14942.09935 1.116024277 1.030769046 1.011790455 1.141101809 1.164905808 1.070512804 0.929414872 0.433401942 1.028250248 1 13.86709524 -4.260035674 2.492908696 1.065751789 0.291850809 0.92802905 0.053175925 0.113271879 0.864200343 0.008864462 0.185785879 5.49E-05 4.260035674 -0.77390098 down S(ph)AVLLVDETATTPIFANR ddPTM_HeLa_Curcumin_4h_R1 3 SAVLLVDETATTPIFANR 18 0 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2;A0A087WY36;A0A087WX73 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 S(1)AVLLVDETATTPIFANR;S(0.958)AVLLVDET(0.024)AT(0.014)T(0.004)PIFANR;S(0.946)AVLLVDET(0.015)AT(0.015)T(0.024)PIFANR ;; 215.15 6.44E-17 99181200 2438.04 2340.49 2642.62 2656.35 2753.27 3419.67 2343.45 994.04 2317.2 2050.62 TRUE FALSE FALSE 2245.066561 2542.791527 2740.557822 2645.358728 2720.439053 2710.391894 2409.2009 1297.11822 2063.008957 2121.878892 1.058055938 1.198367888 1.291571273 1.246705803 1.282089691 1.277354662 1.13540924 0.611306434 0.972255752 1 11.0511266 -7.420856644 3.576342583 1.024165316 1.167436598 0.095644255 0.190225724 0.423330814 9.637798483 0.033436601 0.03758222 3.79E-08 7.420856644 0.143271282 S(ph)AVLLVDETATTPIFANRR ddPTM_HeLa_Curcumin_4h_R1 1 SAVLLVDETATTPIFANRR 19 1 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2;A0A087WY36;A0A087WX73 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 S(1)AVLLVDETATTPIFANRR 145.19 6.47E-05 3875000 528.25 544.44 439.14 481.69 525.4 677.76 417.05 293.82 663.95 498.41 TRUE FALSE FALSE 486.4384551 591.4989676 455.4149147 479.6968944 519.1349481 537.1849361 428.7513006 383.4043654 591.1163461 515.7297104 0.943204251 1.146916603 0.8830496 0.930132363 1.006602757 1.041601686 0.831348848 0.743421133 1.1461747 1 9.010471349 -4.595585254 4.494531875 0.981359183 0.761070896 0.509057417 0.085831041 0.096951514 3.632576782 0.009181152 0.039062043 2.54E-05 4.595585254 -0.220288287 S(ph)AVPPGADKK ddPTM_HeLa_Curcumin_4h_R1 1 SAVPPGADKK 10 1 P46783;F6U211;A0A2R8Y7H1;S4R435;A0A2R8YFH6;A0A1W2PQS6 P46783 RPS10;RPS10-NUDT3 40S ribosomal protein S10 1 0 S(1)AVPPGADKK 85.973 0.011476 6846700 3008.2 2931.7 2415.7 3184.6 3049.9 4308.8 4860.1 4251.1 3759.8 3431.4 TRUE FALSE FALSE 2770.097796 3185.103085 2505.227967 3171.422969 3013.531934 3415.10631 4996.461326 5547.24082 3347.359347 3550.640895 0.780168392 0.897050189 0.70557064 0.893197331 0.848729011 0.961828135 1.407199848 1.562320996 0.942747928 1 11.79386374 -4.729029821 2.817233784 0.87628207 1.544265562 0.909188396 0.077807422 0.066817319 1.035837166 0.013852475 0.064686848 1.87E-05 4.729029821 0.667983492 S(ph)CFRAGVRY(ph)Y(ph)VR ddPTM_HeLa_Curcumin_4h_R1 1 SCFRAGVRYYVR 12 2 F8WDN7;E9PGZ4;A0A5F9ZHN7;Q9NTJ5-2;Q9NTJ5 F8WDN7 SACM1L Phosphatidylinositide phosphatase SAC1 3 0 S(1)CFRAGVRY(1)Y(1)VR 52.344 0.018498 2773200 377.22 258.02 254.13 339.1 245.29 370.79 329.59 345.85 294.89 340.44 TRUE FALSE FALSE 347.362639 280.3220991 263.5482814 337.696894 242.365077 293.8839743 338.8374084 451.2980729 262.5413048 352.2702647 0.986068578 0.795758618 0.748142287 0.958630143 0.688008899 0.834257114 0.961867754 1.281113163 0.745283753 1 8.460538891 -7.399659684 9.0748858 0.993862565 0.884443379 0 0.172692486 0.604928221 42.30762392 0.026214546 0.029930128 3.98E-08 7.399659684 -0.109419186 S(ph)CHDLDLLGQSPGWGQTQAVETNIVCK ddPTM_HeLa_Curcumin_4h_R1 2 SCHDLDLLGQSPGWGQTQAVETNIVCK 27 0 Q9P0V3-2;Q9P0V3 Q9P0V3-2 SH3BP4 SH3 domain-binding protein 4 1 0 S(1)CHDLDLLGQSPGWGQTQAVETNIVCK;S(1)CHDLDLLGQSPGWGQTQAVETNIVCK ; 138.09 4.84E-09 43376000 1185.22 1096.01 1086.23 1183.24 1073 1208.3 778.08 969.86 1471.64 1291.02 TRUE FALSE FALSE 1091.408586 1190.744221 1126.486639 1178.344066 1060.205176 957.6849597 799.9108307 1265.565849 1310.204774 1335.882849 0.816994235 0.891353775 0.843252565 0.882071409 0.793636341 0.716892922 0.598788158 0.9473629 0.980778198 1 10.38357778 -13.52287875 0.127394865 1.697178461 0.703881744 0.41694888 0.089333546 57.23886999 0.519661277 10.14906069 0.344355905 3.00E-14 13.52287875 -0.993296718 S(ph)CPELTSGPR ddPTM_HeLa_Curcumin_4h_R1 4 SCPELTSGPR 10 0 Q13111;Q13111-3;Q13111-2 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 0 S(1)CPELTSGPR;S(1)CPELTSGPR;S(1)CPELTSGPR;S(0.999)CPELT(0.001)SGPR ;;; 218.07 1.47E-10 197911000 4389.44 3953.82 4664.18 4699.13 5059.81 5350.24 4163.28 2982.37 5390.33 4317.76 TRUE FALSE FALSE 4042.011192 4295.570583 4837.038614 4679.686245 4999.47507 4240.539914 4280.090432 3891.680884 4799.024285 4467.801839 0.904697956 0.961450561 1.082643946 1.047424755 1.119001077 0.949133392 0.957985736 0.871050468 1.074135438 1 12.12534948 -4.246113874 2.129478358 0.981459892 0.839096927 0.17451263 0.070482563 1.06810291 5.154284349 0.010866991 0.293666189 5.67E-05 4.246113874 -0.142362965 S(ph)DDTLDEEDSFVMK ddPTM_HeLa_Curcumin_4h_R1 1 SDDTLDEEDSFVMK 14 0 P53355-4;P53355;P53355-3 P53355-4 DAPK1 Death-associated protein kinase 1 1 0 S(1)DDTLDEEDSFVMK 212.87 2.59E-41 0 563.22 448.14 483.21 400.28 544.97 402.64 430.64 206.01 558.8 386.66 TRUE FALSE FALSE 518.6405427 486.8752247 501.1181877 398.6237474 538.4715887 319.1279253 442.7225994 268.8215006 497.501038 400.0964062 1.296288931 1.216894771 1.252493599 0.99631924 1.3458546 0.797627573 1.106539805 0.671891815 1.243452904 1 8.64420386 -3.732817028 0.830634739 1.154705133 6.85E-12 0.475484013 0.153879319 3.798750137 1.043137088 0.025517713 4.956309535 0.000185005 3.732817028 -1.154705133 S(ph)DEEASPLHPACSQK ddPTM_HeLa_Curcumin_4h_R1 1 SDEEASPLHPACSQK 15 0 Q5VVD7;Q8IWE5 Q5VVD7 PLEKHM2 Pleckstrin homology domain-containing family M member 2 1 0 S(0.901)DEEAS(0.099)PLHPACSQK 68.845 0.014765 10317000 2383.5 2868.8 2694.3 2622.3 2525.9 3629.8 2289.9 1086.6 2682.4 2113.5 TRUE FALSE FALSE 2194.84346 3116.766289 2794.153128 2611.449617 2495.780292 2876.938564 2354.148431 1417.899338 2388.147431 2186.943968 1.003612115 1.425169705 1.277651906 1.194109065 1.141218216 1.315506298 1.07645576 0.648347355 1.092002112 1 11.09470054 -7.447344856 24.99995809 1.001588694 1.16675361 0.066195597 0.196896144 190.5378292 63063.0583 0.032987003 0.037721813 3.57E-08 7.447344856 0.165164916 S(ph)DENIPGGVMR ddPTM_HeLa_Curcumin_4h_R1 1 SDENIPGGVMR 11 0 O75976-2;O75976 O75976-2 CPD Carboxypeptidase D 1 0 S(1)DENIPGGVMR 99.568 0.011354 12514000 798.86 782.25 949.59 799.22 843.33 763.95 506.25 585.55 776.66 734.95 TRUE FALSE FALSE 735.629388 849.8642044 984.7826407 795.9130394 833.2738405 605.4981585 520.4540125 764.0814995 691.4623411 760.4894578 0.967310435 1.117522663 1.294932666 1.046579977 1.095707287 0.796195335 0.684367163 1.004723329 0.909233302 1 9.570784439 -5.253388458 24.63101454 1.029516364 0.814022443 0.406051228 0.12472661 411.4896573 1258907.819 0.017991968 0.044968792 5.58E-06 5.253388458 -0.21549392 S(ph)DIGAHQPGMSLSSS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SDIGAHQPGMSLSSSK 16 0 Q92599 Q92599 8-Sep Septin-8 2 0 S(0.997)DIGAHQPGMS(0.003)LS(0.002)S(0.036)S(0.962)K 98.227 0.001176 0 2510.9 2366.8 2107.4 2274.2 2576.2 2983.3 2103.2 2202.2 3142.8 2368.1 TRUE FALSE FALSE 2312.159616 2571.375646 2185.502098 2264.789963 2545.480498 2364.529951 2162.210132 2873.640642 2798.042703 2450.391299 0.943587915 1.049373481 0.891899224 0.92425645 1.03880572 0.964960148 0.882393817 1.172727247 1.141875873 1 11.25879643 -4.245623797 24.68708439 0.968482401 1.172727428 0.347803615 0.076427547 1407.954096 2197682.465 0.007081125 0.236089899 5.68E-05 4.245623797 0.204245027 S(ph)DISPLT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SDISPLTPR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 S(1)DISPLT(1)PR 132.86 0.015618 14386000 3410.6 2905.5 2950.4 2419.3 3317 3394.8 2417.7 2624.6 2650.7 2342.1 TRUE FALSE FALSE 3140.647411 3156.638473 3059.744419 2409.289578 3277.446941 2690.680213 2485.534155 3424.828458 2359.924842 2423.487801 1.295920454 1.302518821 1.262537579 0.994141409 1.352367831 1.110251189 1.025602091 1.413181637 0.973772115 1 11.2428691 -9.42862204 1.169370871 1.000509948 1.218119705 0.331294056 0.131103655 0.492021625 1.207803058 0.085756924 0.02175101 3.73E-10 9.42862204 0.217609757 S(ph)DISPLTPR ddPTM_HeLa_Curcumin_4h_R1 1 SDISPLTPR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(0.989)DIS(0.011)PLTPR 119.22 0.0064363 7578100 1317.7 1082.7 1236.4 1147.2 1470.9 1229.9 957.67 817.66 1266.6 946.95 TRUE FALSE FALSE 1213.402655 1176.283764 1282.222072 1142.45319 1453.360478 974.8048762 984.5396428 1066.96077 1127.657149 979.856442 1.238347377 1.200465408 1.30858156 1.165939357 1.483238172 0.994844586 1.004779476 1.088894989 1.150839144 1 9.936426586 -2.738952032 6.880804353 1.143567687 0.695917671 0 0.148445625 3727551.496 1483777.706 0.021752922 5104792.388 0.001824097 2.738952032 -0.447650017 S(ph)DKSPDLAPTPAPQSTPR ddPTM_HeLa_Curcumin_4h_R1 3 SDKSPDLAPTPAPQSTPR 18 1 F8WAE5;Q9BY44-2;Q9BY44-4;Q9BY44-3;Q9BY44 F8WAE5 EIF2A "Eukaryotic translation initiation factor 2A;Eukaryotic translation initiation factor 2A, N-terminally processed" 1 0 S(0.5)DKS(0.5)PDLAPTPAPQSTPR;S(0.761)DKS(0.239)PDLAPTPAPQSTPR;S(0.883)DKS(0.117)PDLAPTPAPQSTPR ;; 161.1 0.00013333 1167318000 15111.4 13214.7 13701.2 13654.7 13679.1 15862.9 13538.6 13940.1 15180 13234 TRUE FALSE FALSE 13915.31674 14356.91978 14208.97852 13598.20047 13515.98567 12572.75573 13918.45668 18190.37232 13514.79198 13693.88051 1.016170451 1.048418655 1.037615197 0.993012934 0.987009172 0.918129504 1.016399746 1.328357751 0.986922002 1 13.74124371 -4.26316957 6.007069031 1.004303849 1.336818874 0.894780532 0.033737416 0.029467748 5.131395876 0.004757323 0.039962727 5.46E-05 4.26316957 0.332515025 RIS(ph)EMEEELK ddPTM_HeLa_Curcumin_4h_R1 1 RISEMEEELK 10 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 RIS(1)EMEEELK 176.99 0.00017269 15337000 3553.1 2948.8 2859.5 2981.7 3125.8 4817 5586.1 14548 3949.9 2654 TRUE FALSE FALSE 3271.868386 3203.681132 2965.475585 2969.362515 3088.526877 3817.899901 5742.830932 18983.61823 3516.605852 2746.226302 1.191405232 1.166575795 1.079836568 1.081251939 1.124643979 1.390234992 2.091171775 6.912619769 1.280522967 1 11.4232348 -4.192164159 2.231055498 1.110327467 9.103806307 0.995179014 0.119365248 0.038735022 0.187432579 0.018073499 0.649288694 6.42E-05 4.192164159 7.993478839 up S(ph)DSDLIAYPSNEK ddPTM_HeLa_Curcumin_4h_R1 1 SDSDLIAYPSNEK 13 0 H0YI72;Q7Z6G8-6;Q7Z6G8 H0YI72 ANKS1B Ankyrin repeat and sterile alpha motif domain-containing protein 1B 1 0 S(0.999)DS(0.001)DLIAYPSNEK 89.356 0.013071 5790400 2121.5 1976.5 1951.3 2523.5 2262.3 498.25 885.43 909.23 2503.6 2152 TRUE FALSE FALSE 1953.581036 2147.339853 2023.616895 2513.058426 2235.32355 394.9073336 910.2727828 1186.450041 2228.961344 2226.78184 0.877311374 0.964324306 0.908762977 1.128560679 1.003835899 0.17734442 0.408783998 0.532809286 1.000978768 1 11.12074451 -5.270822972 24.99384258 0.957878938 0.376559708 0.87713687 0.104384033 159.3933239 424555.2148 0.015280285 0.03459703 5.36E-06 5.270822972 -0.58131923 S(ph)DSDLLTCSPTEDATMGSR ddPTM_HeLa_Curcumin_4h_R1 3 SDSDLLTCSPTEDATMGSR 19 0 A0A3B3ISP1;Q92625 A0A3B3ISP1 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 0 S(0.99)DS(0.01)DLLTCSPTEDATMGSR;S(1)DSDLLTCSPTEDATMGSR;S(0.79)DS(0.205)DLLT(0.003)CS(0.001)PT(0.001)EDATMGSR ;; 225.17 4.26E-21 19832900 3076.83 2937.4 3192.81 3105.33 3283.39 2963.51 1815.6 1088.77 3075.63 2409.15 TRUE FALSE FALSE 2833.295659 3191.295767 3311.138347 3092.480967 3244.237719 2348.84462 1866.54085 1420.730961 2738.241084 2492.867783 1.136560743 1.280170488 1.328244671 1.240531483 1.301407857 0.942225912 0.748752446 0.569918297 1.09843013 1 11.28359065 -4.784114225 2.350382077 1.129694768 0.606068258 0.768370859 0.115200664 0.147202313 1.563336362 0.020759668 0.10139184 1.64E-05 4.784114225 -0.52362651 S(ph)DSELEVKPAESLLR ddPTM_HeLa_Curcumin_4h_R1 1 SDSELEVKPAESLLR 15 1 Q92539 Q92539 LPIN2 Phosphatidate phosphatase LPIN2 1 0 S(0.966)DS(0.034)ELEVKPAESLLR 101.08 0.0015706 5873400 2114.3 1509 1721.4 2204 2162.9 2291.4 1916.5 1676.6 1768.9 1620 TRUE FALSE FALSE 1946.950924 1639.431236 1785.196598 2194.880432 2137.10883 1816.137811 1970.271832 2187.787622 1574.856096 1676.294879 1.161460879 0.978008855 1.064965729 1.309364157 1.274900291 1.083423825 1.175373054 1.305132915 0.939486313 1 10.71106024 -6.284385763 23.7423519 1.06848245 1.221015546 0.54609303 0.087733789 314.7619968 325679.7797 0.013895734 0.021237053 5.20E-07 6.284385763 0.152533096 S(ph)DSLLSFR ddPTM_HeLa_Curcumin_4h_R1 5 SDSLLSFR 8 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 0 S(0.999)DS(0.001)LLSFR;S(0.964)DS(0.035)LLS(0.001)FR;S(0.981)DS(0.019)LLSFR;S(0.996)DS(0.004)LLSFR;S(0.977)DS(0.023)LLSFR ;;;; 160.75 0.00087094 99181400 8658.92 6741.48 7618.75 6953.3 8519.98 10204.3 7776.88 5166.5 7484.96 7110.82 TRUE FALSE FALSE 7973.557345 7324.183492 7901.107577 6924.529087 8418.384803 8087.813154 7995.078322 6741.742066 6663.878614 7357.920466 1.083669956 0.995414877 1.073823455 0.941098659 1.14412555 1.09919823 1.086594828 0.916256447 0.905674184 1 12.84508237 -5.745116946 24.99974532 1.033464744 1.06602267 0.035750201 0.078506573 665.7883094 1019726.295 0.009752108 0.019455578 1.80E-06 5.745116946 0.032557926 S(ph)DSPES(ph)DAEREK ddPTM_HeLa_Curcumin_4h_R1 2 SDSPESDAEREK 12 1 O75400-2;O75400-3;O75400 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 2 0 S(0.963)DS(0.037)PES(1)DAEREK;S(0.997)DS(0.003)PES(1)DAEREK ; 177.21 0.00052983 80467000 9186.8 8749.7 8807.2 8754.2 10990 10585.1 9541.1 8375.9 7896.4 7205 TRUE FALSE FALSE 8459.655086 9505.98508 9133.60258 8717.97744 10858.95143 8389.630941 9808.797587 10929.67335 7030.184676 7455.373214 1.134705781 1.275051538 1.225103334 1.169354932 1.456526872 1.125313341 1.315668218 1.466012906 0.942968846 1 12.86406486 -1.000001378 0.053633394 0.477133908 2.675788212 0.659670694 0.096183177 168.6374246 0.687390644 6.387856282 30.14320539 0.099999683 1.000001378 2.198654304 S(ph)DSPVPTAPTSGGPK ddPTM_HeLa_Curcumin_4h_R1 1 SDSPVPTAPTSGGPK 15 0 Q86U44;B4E349;F5H6D8;B4DTN4 Q86U44 METTL3 N6-adenosine-methyltransferase 70 kDa subunit 1 0 S(0.5)DS(0.5)PVPTAPTSGGPK 184 3.28E-05 6376000 3437.6 3076.6 4189.4 3433.2 4265 2958.8 2577.2 779.32 3112.7 2589.5 TRUE FALSE FALSE 3165.510333 3342.527595 4344.662849 3418.994328 4214.142661 2345.111527 2649.509296 1016.93108 2771.244598 2679.484932 1.181387622 1.247451536 1.621454481 1.275989384 1.572743556 0.875209821 0.988812911 0.379524836 1.034245263 1 11.38773999 -4.188494175 1.51391075 1.177857883 1.66E-12 0.569635164 0.22226604 0.884144799 1.613437829 0.035229997 1.629149581 6.48E-05 4.188494175 -1.177857883 STPLASPS(ph)PSPGRSPQR ddPTM_HeLa_Curcumin_4h_R1 1 STPLASPSPSPGRSPQR 17 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 0 STPLASPS(0.862)PS(0.137)PGRSPQR 117.14 0.0072992 26081000 1870.1 1733.9 1728 2215.4 1991.6 2188 1445.4 591.16 2342.7 1939.7 TRUE FALSE FALSE 1722.079612 1883.77059 1792.0412 2206.233262 1967.851471 1734.184136 1485.954034 771.4019626 2085.711671 2007.104431 0.857992033 0.938551358 0.892849008 1.099211993 0.980442991 0.864022873 0.740347144 0.384335738 1.0391645 1 10.97089997 -4.259838887 1.538723031 0.943522224 0.167183103 0.86375982 0.070748731 0.316505845 0.679641888 0.011033813 0.371178545 5.50E-05 4.259838887 -0.776339121 down SQST(ph)TSDVPANYK ddPTM_HeLa_Curcumin_4h_R1 1 SQSTTSDVPANYK 13 0 Q9NU19 Q9NU19 TBC1D22B TBC1 domain family member 22B 1 0 S(0.001)QS(0.168)T(0.525)T(0.153)S(0.153)DVPANYK 206.67 1.28E-29 0 2288.7 1750 1897.3 2478.9 1921.5 3489.3 4761.4 8125 2366.5 2168.8 TRUE FALSE FALSE 2107.54698 1901.262202 1967.615607 2468.642969 1898.587367 2765.579847 4894.992069 10602.2751 2106.900871 2244.165639 0.939122738 0.847202261 0.876769332 1.100027077 0.846010355 1.232342123 2.181208011 4.724372798 0.938834832 1 11.13196345 -4.191742464 1.573578927 0.954089559 6.612372782 0.994725503 0.083453666 0.06027603 0.121407595 0.012273638 0.549019131 6.43E-05 4.191742464 5.658283223 up S(ph)EDEAGCSSVDEES(ph)Y(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SEDEAGCSSVDEESYK 16 0 Q7L4I2;Q7L4I2-2 Q7L4I2 RSRC2 Arginine/serine-rich coiled-coil protein 2 3 0 S(0.671)EDEAGCS(0.151)S(0.179)VDEES(1)Y(1)K 57.525 0.009195 0 656.11 744.64 891.63 701.5 676.88 597.74 415.18 275.4 933.77 493.95 TRUE FALSE FALSE 604.1782012 809.0033635 924.6745922 698.5973789 668.8086481 473.7619861 426.8288334 359.3681922 831.3377672 511.1147257 1.182079425 1.582821474 1.809133147 1.366811292 1.308529405 0.92691907 0.835093986 0.703106708 1.626518911 1 8.997503347 -5.044039176 3.079391971 1.21572504 0.77424031 0.389300432 0.27322985 0.262017282 4.936023363 0.043049653 0.135258996 9.04E-06 5.044039176 -0.44148473 S(ph)EDEDS(ph)LEEAGSPAPGPCPR ddPTM_HeLa_Curcumin_4h_R1 2 SEDEDSLEEAGSPAPGPCPR 20 0 Q8TBB5-2;Q8TBB5-3;Q8TBB5 Q8TBB5-2 KLHDC4 Kelch domain-containing protein 4 2 0 S(1)EDEDS(1)LEEAGSPAPGPCPR;S(1)EDEDS(1)LEEAGSPAPGPCPR ; 269.85 1.93E-55 30740000 3348.7 2724.92 3114.02 2448.84 3975.7 2984.12 2600.96 1604.61 2877.74 2834.28 TRUE FALSE FALSE 3083.646861 2960.449943 3229.428321 2438.707349 3928.292374 2365.179874 2673.935937 2093.848202 2562.059122 2932.771019 1.051444808 1.009437806 1.101152562 0.831536909 1.339447352 0.806465919 0.911743849 0.71394875 0.873596713 1 11.51804872 QIS(ph)QDVKLEPDILLR ddPTM_HeLa_Curcumin_4h_R1 1 QISQDVKLEPDILLR 15 1 E9PIJ1;A0A590UK85;A0A590UJY6;A0A5F9UK94;H0Y360;Q01433-3;Q01433-5;Q01433-2;Q01433-4;Q01433;E9PJF6 E9PIJ1 AMPD2 AMP deaminase 2 1 0 QIS(1)QDVKLEPDILLR 109.13 0.0010151 24425000 2264.6 1847 1674.6 1818.4 1840.6 3514 3730.3 5593.2 2149.3 2478.4 TRUE FALSE FALSE 2085.35452 2006.64645 1736.662149 1810.875943 1818.652047 2785.156789 3834.962178 7298.540932 1913.527167 2564.524216 0.813154545 0.782463444 0.677186879 0.706125499 0.709157682 1.086032556 1.495389342 2.845962962 0.746152895 1 11.32447548 -4.191445253 1.547111729 0.855735336 3.847852101 0.966360895 0.116114152 0.195759002 0.378303372 0.02059983 0.930448841 6.44E-05 4.191445253 2.992116765 up S(ph)EGFSMDR ddPTM_HeLa_Curcumin_4h_R1 1 SEGFSMDR 8 0 Q7Z4V5-2;Q7Z4V5;Q7Z4V5-4;Q7Z4V5-3;K7ERA4 Q7Z4V5-2 HDGFRP2 Hepatoma-derived growth factor-related protein 2 1 0 S(1)EGFSMDR 128.91 0.0056139 19318000 2518.6 2006.3 2205.3 2205.8 2205.1 2335 1331.3 1450.7 2467.7 1846 TRUE FALSE FALSE 2319.250152 2179.715632 2287.030358 2196.672984 2178.805623 1850.694679 1368.652695 1893.011752 2196.999484 1910.148363 1.214172782 1.141123734 1.19730509 1.150001239 1.140647326 0.968874835 0.716516435 0.991028649 1.150172168 1 10.89946898 -5.060271294 4.096352691 1.119194571 0.849858792 0.655670401 0.08423993 0.119998119 4.017012109 0.014335315 0.040634297 8.70E-06 5.060271294 -0.269335778 S(ph)EGSEYEEIPK ddPTM_HeLa_Curcumin_4h_R1 2 SEGSEYEEIPK 11 0 P48634 P48634 PRRC2A Protein PRRC2A 1 0 S(1)EGSEYEEIPK;S(1)EGSEYEEIPK ; 179.59 0.00016065 26779000 6552.9 4795 6741 5746.2 6695.4 5208.5 3967.8 2936.7 5178.3 4844 TRUE FALSE FALSE 6034.23105 5209.458434 6990.82739 5722.423747 6615.561728 4128.198388 4079.125789 3832.086311 4610.253445 5012.328639 1.203877775 1.039328984 1.394726462 1.141669703 1.319857935 0.823608882 0.813818503 0.764532134 0.919782755 1 12.29126529 -5.167357377 7.466149466 1.133151195 0.798136793 0.577651497 0.134953332 0.153936542 10.78065255 0.018546634 0.04763253 6.80E-06 5.167357377 -0.335014401 S(ph)EHSLFQAK ddPTM_HeLa_Curcumin_4h_R1 1 SEHSLFQAK 9 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 S(0.85)EHS(0.15)LFQAK 87.184 0.0056798 0 4760.4 5044.3 5199 5060.3 5736.2 4167.2 3875.9 3542.5 4715.3 4914.3 TRUE FALSE FALSE 4383.609317 5480.306815 5391.679514 5039.361819 5667.799561 3302.875746 3984.647323 4622.591942 4198.043387 5085.071559 0.862054598 1.07772462 1.060295701 0.991010994 1.114595831 0.649523946 0.783597099 0.909051503 0.825562303 1 12.31205236 -5.258784209 24.99918264 0.968786451 0.781011481 0.450277068 0.104194452 182.217159 1715613.158 0.014941578 0.036261534 5.51E-06 5.258784209 -0.18777497 S(ph)ELEFETLK ddPTM_HeLa_Curcumin_4h_R1 1 SELEFETLK 9 0 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 S(1)ELEFETLK 181.53 0.0013572 4772500 1634 1345.9 1618.7 1478.7 2064.2 3163.5 2666.4 1479.7 1516.5 1325.7 TRUE FALSE FALSE 1504.667176 1462.233599 1678.690446 1472.581531 2039.585763 2507.35444 2741.212008 1930.853718 1350.143744 1371.767976 1.09688169 1.065948195 1.223742262 1.073491696 1.486829988 1.827826924 1.998305876 1.407565821 0.984236232 1 10.42182077 -5.602914057 2.651978415 1.062586484 1.767480426 0.802249797 0.150989284 0.077994646 1.106224842 0.020983307 0.047177379 2.50E-06 5.602914057 0.704893941 S(ph)ESELIDELSEDFDRSECK ddPTM_HeLa_Curcumin_4h_R1 2 SESELIDELSEDFDRSECK 19 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E7EVY3;E9PCH5;P20810-3;E7EQ12;E7EQA0;H0Y7F0;A0A0A0MR45;H0Y9H6;H0YD33;D6RC54 P20810-6 CAST Calpastatin 1 0 S(0.996)ES(0.004)ELIDELSEDFDRSECK;S(0.996)ES(0.004)ELIDELSEDFDRSECK ; 231.39 1.83E-25 1074330000 4530 3805.9 4315.6 3573.63 4176.1 4896.6 3682.42 5677.3 3907.4 3932.8 TRUE FALSE FALSE 4171.44572 4134.865037 4475.539932 3558.843266 4126.302735 3880.989964 3785.738794 7408.282635 3478.767996 4069.464507 1.025060106 1.016071041 1.099785961 0.874523727 1.013967004 0.953685665 0.930279349 1.820456382 0.854846624 1 11.99062325 -4.258422425 24.9987753 1.001234221 1.820456681 0.920034598 0.074460904 41.63213959 344950.1633 0.007645548 0.072007537 5.52E-05 4.258422425 0.81922246 S(ph)ESETSTMAAK ddPTM_HeLa_Curcumin_4h_R1 1 SESETSTMAAK 11 0 A0A087WVF1;Q96B23-2;Q96B23 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 0 S(0.999)ES(0.001)ETSTMAAK 136.27 0.0019055 27382000 1532.4 1419.5 1812.7 1810.5 1655.6 1758.3 1211.5 1363.9 1722.4 1673.7 TRUE FALSE FALSE 1411.108923 1542.195255 1879.880257 1803.008631 1635.858051 1393.60876 1245.491429 1779.746831 1533.457029 1731.86095 0.814793429 0.890484455 1.085468355 1.041081635 0.944566624 0.804688598 0.719163643 1.027649957 0.885438885 1 10.75810739 -5.269929583 23.82314486 0.934002298 0.837367024 0.147550306 0.104204478 520.4168727 1460270.811 0.016671765 0.037884701 5.37E-06 5.269929583 -0.096635274 S(ph)ESPPAELPSLR ddPTM_HeLa_Curcumin_4h_R1 2 SESPPAELPSLR 12 0 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 0 S(0.641)ES(0.359)PPAELPSLR;S(0.942)ES(0.058)PPAELPSLR ; 155.47 0.00034 186533000 5923.5 5261.6 5600.1 6213.7 6529 6829.4 5221.7 3357.7 6265.4 5169.5 TRUE FALSE FALSE 5454.648725 5716.389259 5807.644632 6187.989356 6451.145939 5412.905457 5368.206849 4381.447273 5578.101295 5349.13974 1.019724477 1.068655809 1.085715632 1.156819537 1.206015594 1.011920742 1.003564519 0.819093814 1.042803435 1 12.38509118 -4.226186002 2.346623402 1.043669845 0.752971199 0.536799538 0.067041596 0.504896986 3.032462964 0.011194168 0.308716569 5.94E-05 4.226186002 -0.290698646 S(ph)ESPQEALLLPR ddPTM_HeLa_Curcumin_4h_R1 1 SESPQEALLLPR 12 0 H7BY14;A0A087WYU3;Q96NU1-6;Q96NU1;I7G285 H7BY14 SAMD11 Sterile alpha motif domain-containing protein 11 1 0 S(0.956)ES(0.044)PQEALLLPR 118.52 0.003717 3703400 1729.5 1405.3 1471.9 1327.1 1426.6 1717.5 1189.3 916.97 1573.7 1342.9 TRUE FALSE FALSE 1592.60825 1526.76787 1526.449909 1321.608812 1409.588727 1361.27114 1222.668557 1196.549932 1401.069047 1389.565675 1.146119452 1.098737467 1.098508646 0.951094889 1.014409576 0.979637857 0.879892602 0.861096351 1.008278394 1 10.44041831 -5.01060204 0.799017988 1.072595701 0.826471434 0.65333848 0.051820555 0.602730752 0.500071139 0.010917344 0.104757053 9.76E-06 5.01060204 -0.246124266 TTPATGEQS(ph)PGAR ddPTM_HeLa_Curcumin_4h_R1 2 TTPATGEQSPGAR 13 0 O00308-4;O00308-2;O00308 O00308-4 WWP2 NEDD4-like E3 ubiquitin-protein ligase WWP2 1 0 TTPATGEQS(1)PGAR;TTPATGEQS(1)PGAR ; 175.6 0.00021453 227100000 6989.8 6278.9 5700.7 6375.4 5878.9 6269.6 4467.4 1399.07 6923.8 5746 TRUE FALSE FALSE 6436.549954 6821.620138 5911.972957 6349.020284 5808.797957 4969.214287 4592.743221 1825.640002 6164.276462 5945.673072 1.082560355 1.147325131 0.994331993 1.067838781 0.976979038 0.835769849 0.772451355 0.307053546 1.036766803 1 12.53762442 -4.259800544 1.037273356 1.045795805 1.91E-18 0.937823953 0.057582837 0.323278955 0.268079482 0.009102389 0.373761548 5.50E-05 4.259800544 -1.045795805 down LPSS(ph)PVYEDAASFK ddPTM_HeLa_Curcumin_4h_R1 2 LPSSPVYEDAASFK 14 0 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 1 0 LPS(0.001)S(0.999)PVYEDAASFK;LPS(0.003)S(0.997)PVYEDAASFK ; 154.72 0.00040764 1258613000 8270.1 6700.3 7364.1 7808.5 8534 9023.9 10393.9 17304.3 6353 5634.8 TRUE FALSE FALSE 7615.512858 7279.444076 7637.020024 7776.190496 8432.237624 7152.24142 10685.52486 22580.30141 5656.091794 5830.608881 1.306126515 1.248487804 1.309815181 1.333684124 1.446201897 1.226671445 1.832660204 3.872717562 0.970068806 1 12.50943083 -4.19110724 1.945933644 1.201290798 5.021357322 0.968786605 0.142259712 0.127492876 0.433109361 0.023294428 0.924372227 6.44E-05 4.19110724 3.820066524 up S(ph)FAGNLNTYK ddPTM_HeLa_Curcumin_4h_R1 1 SFAGNLNTYK 10 0 Q01813;Q01813-2;B1APP6 Q01813 PFKP "ATP-dependent 6-phosphofructokinase, platelet type" 1 0 S(1)FAGNLNTYK 110.15 0.007542 46954000 1891 1558.2 1734 1373.3 1942.4 1768 2116.2 1867.9 1495.1 1476.8 TRUE FALSE FALSE 1741.325355 1692.883865 1798.263565 1367.617648 1919.238149 1401.296871 2175.574877 2437.414111 1331.091271 1528.11869 1.13952232 1.107822236 1.176782652 0.89496821 1.255948351 0.917007874 1.423694959 1.595042405 0.871065369 1 10.57754089 -4.610735175 4.914543737 1.072024531 1.557298141 0.693284682 0.124459992 0.065433714 2.636832995 0.014019376 0.057033604 2.45E-05 4.610735175 0.48527361 S(ph)FAGNLNTYKR ddPTM_HeLa_Curcumin_4h_R1 1 SFAGNLNTYKR 11 1 Q01813;Q01813-2;B1APP6 Q01813 PFKP "ATP-dependent 6-phosphofructokinase, platelet type" 1 0 S(1)FAGNLNTYKR 74.537 0.016139 53507000 1985.5 1519.1 1539.7 1714.8 1693.5 2939 2170 2196.5 2244.3 2529.5 TRUE FALSE FALSE 1828.34558 1650.404235 1596.762636 1707.704612 1673.306119 2329.418271 2230.88436 2866.202739 1998.105905 2617.399937 0.698535044 0.630551033 0.610056803 0.652443132 0.639300894 0.889974145 0.852328423 1.095057235 0.763393426 1 11.35391867 -4.120339703 1.633659237 0.791775168 1.284975185 0.371685647 0.127587117 1.821635207 3.490982991 0.024987422 1.572726364 7.58E-05 4.120339703 0.493200018 S(ph)FDDPIVQTER ddPTM_HeLa_Curcumin_4h_R1 4 SFDDPIVQTER 11 0 D6RJ96;E9PDE8;O95757 D6RJ96 HSPA4L Heat shock 70 kDa protein 4L 1 0 S(1)FDDPIVQTER;S(1)FDDPIVQTER;S(1)FDDPIVQTER;S(1)FDDPIVQTER ;;; 219.89 3.30E-11 26326300 5930.75 4854.18 4271.73 4601.47 5874.6 10101.3 9722.4 4366.42 8821.9 4527.13 TRUE FALSE FALSE 5461.324879 5273.753689 4430.044072 4582.430336 5804.549232 8006.176515 9995.184377 5697.721357 7854.159641 4684.447431 1.165841854 1.125800592 0.945691917 0.978222171 1.239110763 1.709097313 2.133695495 1.216305966 1.676645913 1 12.19366316 -5.349040056 3.470803927 1.06813551 1.735794592 0.389292514 0.29017738 0.104381404 2.386003124 0.028996435 0.070605437 4.48E-06 5.349040056 0.667659081 S(ph)FDGNTLLNR ddPTM_HeLa_Curcumin_4h_R1 1 SFDGNTLLNR 10 0 Q05209-2;Q05209-3;Q05209 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 0 S(1)FDGNTLLNR 94.402 0.016292 4939700 3235.6 3418.6 2966 3655.1 2884.5 3030.6 2321.5 2487.6 3942.6 3377.2 TRUE FALSE FALSE 2979.498846 3714.088551 3075.922569 3639.976165 2850.104221 2402.019398 2386.635042 3246.057788 3510.106644 3494.557449 0.852611207 1.062820859 0.88020375 1.041612913 0.815583737 0.687360112 0.682957736 0.928889519 1.004449546 1 11.77089405 -5.571332065 7.101305442 0.94236266 0.756850017 0.5101274 0.091312405 0.13679482 16.05628787 0.013355214 0.026927065 2.68E-06 5.571332065 -0.185512643 S(ph)FDHLISDTK ddPTM_HeLa_Curcumin_4h_R1 3 SFDHLISDTK 10 0 H0Y465;P21359-2;P21359-6;P21359;J3QSG6 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 0 S(1)FDHLISDTK;S(1)FDHLISDTK;S(1)FDHLISDTK ;; 134.98 0.0014235 20093700 15601.7 15053.2 15321 14399.6 13686.9 28694.4 25945.9 14333.6 18993.8 17126.5 TRUE FALSE FALSE 14366.80898 16354.33153 15888.80974 14340.01827 13523.69266 22742.85799 26673.87212 18703.84866 16910.22766 17721.6446 0.810692761 0.922845024 0.89657648 0.80918101 0.763117248 1.28333789 1.50515783 1.055423979 0.954213226 1 14.11322487 -5.247050501 22.97766231 0.892235228 1.303691894 0.692638097 0.122175584 116.0924501 185386.8974 0.017454699 0.044213575 5.66E-06 5.247050501 0.411456666 S(ph)FDYNYR ddPTM_HeLa_Curcumin_4h_R1 3 SFDYNYR 7 0 Q5JRI1;O75494-5;O75494-4;O75494-6;O75494-3;O75494-2;O75494 Q5JRI1 SRSF10 Serine/arginine-rich splicing factor 10 1 0 S(0.52)FDY(0.013)NY(0.467)R;S(0.994)FDYNY(0.006)R;S(0.89)FDY(0.004)NY(0.107)R ;; 107.79 0.016633 1299010000 10216.4 9864.7 10052.7 9991.4 11343.7 10543.5 9372.4 9102.7 8179.4 7925.3 TRUE FALSE FALSE 9407.76116 10717.36071 10425.26191 9950.058234 11208.43379 8356.65925 9635.364319 11878.07133 7282.140284 8200.703585 1.147189514 1.306883074 1.271264325 1.21331763 1.366764896 1.019017352 1.174943615 1.448421005 0.887989696 1 13.00153198 -8.094450296 0.823883991 1.020855316 1.248148555 0.487392291 0.119166762 0.376968728 0.553264082 0.036836324 0.025693292 8.05E-09 8.094450296 0.227293239 RMYS(ph)FDDVLEEGK ddPTM_HeLa_Curcumin_4h_R1 1 RMYSFDDVLEEGK 13 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424;E9PJ10 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 RMYS(1)FDDVLEEGK 77.506 0.015804 7101100 4246.9 3891.7 4168.1 3493.4 4870 5668.5 6849.1 10509 4450.2 4309.3 TRUE FALSE FALSE 3910.753384 4228.081207 4322.573453 3478.945236 4811.928431 4492.789203 7041.267313 13713.14572 3962.024194 4459.047854 0.877037769 0.948202698 0.969393824 0.780199125 1.0791381 1.00756694 1.579096602 3.075352894 0.888535921 1 12.12251997 -4.190631412 1.686280234 0.938155041 4.103240333 0.986400597 0.075955259 0.088210917 0.209742725 0.010952881 0.474976474 6.45E-05 4.190631412 3.165085292 up S(ph)FEMTEFNQALEEIK ddPTM_HeLa_Curcumin_4h_R1 1 SFEMTEFNQALEEIK 15 0 Q9BVS4;Q9BVS4-2;H0Y919 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 0 S(0.99)FEMT(0.01)EFNQALEEIK 86.214 0.012553 1603300 644.11 519.03 721.94 631.74 745.12 826.38 690.9 572.82 614.41 549.25 TRUE FALSE FALSE 593.1280138 563.8926404 748.6957315 629.1260273 736.2349307 654.9794728 710.2847945 747.4701811 547.0107602 568.3363966 1.043621379 0.992181116 1.317346093 1.10696065 1.295421048 1.152450339 1.249761231 1.315189711 0.962477088 1 9.150601299 -6.771110257 24.99998045 1.019043189 1.23254457 0.750464646 0.067339334 71.52664369 184901.8231 0.009638839 0.012757565 1.69E-07 6.771110257 0.213501381 S(ph)FEVEEVETPNS(ph)TPPRR ddPTM_HeLa_Curcumin_4h_R1 1 SFEVEEVETPNSTPPRR 17 1 Q9UHD8;Q9UHD8-5;Q9UHD8-2;Q9UHD8-7;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 9-Sep Septin-9 2 0 S(1)FEVEEVETPNS(0.608)T(0.392)PPRR 82.593 0.0033108 14925000 1015 1066.3 1002.8 986.79 947.77 1361.8 1629.5 688.16 1283.2 1215.7 TRUE FALSE FALSE 934.661679 1158.466221 1039.96465 982.7069244 936.4684618 1079.347329 1675.219384 897.9768161 1142.43617 1257.945485 0.743006506 0.920919257 0.826716788 0.78119993 0.744442802 0.858023931 1.331710639 0.713843984 0.908176216 1 10.29685369 -4.914496871 24.9280051 0.857833096 1.040802621 0.159129396 0.158473923 29.36672155 8557.585833 0.021917545 0.065752648 1.22E-05 4.914496871 0.182969525 S(ph)FEVEEVETPNST(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 1 SFEVEEVETPNSTPPR 16 0 Q9UHD8;Q9UHD8-5;Q9UHD8-2;Q9UHD8-7;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 9-Sep Septin-9 2 0 S(1)FEVEEVET(0.032)PNS(0.253)T(0.716)PPR 169.67 0.00060634 11344000 2265.8 2243.5 1586.1 2398.2 2311.1 3101.8 2877 1246.2 1946.6 2035 TRUE FALSE FALSE 2086.459539 2437.418143 1644.882261 2388.276884 2283.541642 2458.451716 2957.720877 1626.160643 1733.06285 2105.716099 0.990855102 1.15752458 0.781151012 1.134187503 1.084448964 1.167513378 1.404615218 0.772260156 0.823027782 1 11.04009522 S(ph)FEVEEVETPNST(ph)PPRR ddPTM_HeLa_Curcumin_4h_R1 1 SFEVEEVETPNSTPPRR 17 1 Q9UHD8;Q9UHD8-5;Q9UHD8-2;Q9UHD8-7;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 9-Sep Septin-9 2 0 S(0.999)FEVEEVET(0.001)PNS(0.268)T(0.732)PPRR 109.32 0.00091603 17719000 1053.4 1126 1189.7 1309.8 1190.4 1769.2 1861.2 916.96 1407.2 1337.9 TRUE FALSE FALSE 970.0222785 1223.326423 1233.791329 1304.380395 1176.205257 1402.247977 1913.420263 1196.536883 1252.833681 1384.391925 0.700684727 0.883656138 0.891215346 0.942204567 0.849618692 1.012898119 1.382137694 0.864305014 0.904970376 1 10.43503672 -5.026886697 5.877362437 0.867699371 1.141341191 0.331729761 0.137340257 0.135071003 15.29746197 0.0210599 0.057673957 9.40E-06 5.026886697 0.273641819 RDS(ph)FDDR ddPTM_HeLa_Curcumin_4h_R1 1 RDSFDDR 7 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 0 RDS(1)FDDR 79.07 0.0161 12686000 1495.4 2156.5 1622.9 1469.3 2029.2 2550.2 4277.7 7628.9 1610 1615.5 TRUE FALSE FALSE 1377.037512 2342.898251 1683.046102 1463.220426 2005.003115 2021.259773 4397.720749 9954.916491 1433.387028 1671.638505 0.823765131 1.401557959 1.006824201 0.875321083 1.199423864 1.209148849 2.630784549 5.955184965 0.857474283 1 10.70704718 -4.18816418 1.558985321 0.967596101 8.511919324 0.987166386 0.170612686 0.095980172 0.187801053 0.02538945 1.159948749 6.48E-05 4.18816418 7.544323223 up S(ph)FLNYYADLETSAR ddPTM_HeLa_Curcumin_4h_R1 1 SFLNYYADLETSAR 14 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 0 S(1)FLNYYADLETSAR 188.16 1.27E-05 6453900 762.67 658.31 905.16 990.44 712.38 1063.1 675.54 517.11 902.44 815.86 TRUE FALSE FALSE 702.3038647 715.211383 938.7060259 986.3418217 703.8853338 842.6010764 694.4938343 674.7744585 803.4445898 844.2110743 0.831905534 0.847194979 1.11193285 1.168359255 0.833778844 0.998092897 0.822654257 0.79929591 0.951710555 1 9.721459944 -4.675685223 6.757245731 0.94301344 0.806744462 0.224541999 0.109224883 0.297600067 19.21044233 0.016769006 0.063795862 2.11E-05 4.675685223 -0.136268978 S(ph)FNGTDNHIR ddPTM_HeLa_Curcumin_4h_R1 2 SFNGTDNHIR 10 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 0 S(1)FNGTDNHIR;S(0.937)FNGT(0.063)DNHIR ; 134.06 0.0011083 18794600 1323.01 1164.27 1284.97 1316.5 1423.76 1495.01 1330.82 918.36 1322.99 1301.87 TRUE FALSE FALSE 1218.292362 1264.904311 1332.592119 1311.052672 1406.782592 1184.928074 1368.159227 1198.363736 1177.861307 1347.109886 0.904374896 0.938976341 0.989223027 0.973233651 1.044296836 0.879607585 1.015625557 0.88958128 0.874361713 1 10.39565182 -4.220677127 22.19701549 0.960449572 0.889580388 0.119998761 0.054938466 8700.737539 4737549.129 0.007001995 2.553248551 6.02E-05 4.220677127 -0.070869185 S(ph)FQGDDSDLLLK ddPTM_HeLa_Curcumin_4h_R1 3 SFQGDDSDLLLK 12 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 S(0.999)FQGDDS(0.001)DLLLK;S(0.938)FQGDDS(0.062)DLLLK;S(1)FQGDDSDLLLK ;; 174.18 0.00013908 50204900 8915.4 7032.3 6999 7392.06 7281.6 7331.1 4129.26 3337.92 8440.5 6708.7 TRUE FALSE FALSE 8209.736683 7640.140677 7258.389097 7361.473614 7194.771676 5810.547221 4245.115922 4355.636442 7514.598267 6941.826826 1.182647866 1.100595113 1.045602156 1.060451924 1.036437793 0.837034309 0.6115272 0.627448156 1.082510189 1 12.76109966 -5.040539009 1.800021918 1.084817664 0.599523073 0.941025173 0.045841488 0.088701241 0.539231429 0.010280597 0.043281161 9.11E-06 5.040539009 -0.48529459 S(ph)FRDLRNMS(ph)PRLT(ph)S(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SFRDLRNMSPRLTSR 15 3 I3L257;I3L2E1 I3L257 CLUAP1 4 0 S(1)FRDLRNMS(1)PRLT(1)S(1)R 61.959 0.013023 40834000 0 0 53.333 0 0 0 0 0 0 124.18 TRUE FALSE FALSE 0 0 55.3095679 0 0 0 0 0 0 128.4952458 0 0 0.430440578 0 0 0 0 0 0 1 7.005571171 -9.323516577 0.619439508 1.154652487 0.036650976 0 0.336839968 0.28921412 0.1567634 0.184101211 0.029928825 4.75E-10 9.323516577 -1.118001511 S(ph)FSADNFIGIQR ddPTM_HeLa_Curcumin_4h_R1 2 SFSADNFIGIQR 12 0 Q8N7R7-3;Q8N7R7-2;Q8N7R7 Q8N7R7-3 CCNYL1 Cyclin-Y-like protein 1 1 0 S(0.929)FS(0.071)ADNFIGIQR;S(0.969)FS(0.031)ADNFIGIQR ; 163.33 0.00013544 16579700 2794 2437.1 2538.6 3890.1 2768 4957 2282.29 990.77 4987.6 2704.6 TRUE FALSE FALSE 2572.851952 2647.752064 2632.682749 3874.003797 2734.993408 3928.862323 2346.324915 1292.851212 4440.472758 2798.584649 0.919340408 0.946103976 0.940719356 1.38427251 0.977277357 1.40387475 0.838396979 0.461966092 1.58668517 1 11.45048167 -4.362476469 3.865256636 1.015992752 0.45561268 0.33547963 0.252966655 0.149254053 3.557641528 0.024508257 0.185666457 4.34E-05 4.362476469 -0.560380072 S(ph)FSEDTLMDGPAR ddPTM_HeLa_Curcumin_4h_R1 1 SFSEDTLMDGPAR 13 0 Q9BRG2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 0 S(0.904)FS(0.052)EDT(0.044)LMDGPAR 166.62 0.00018266 26097000 2580.5 2060.1 2089 2173.3 2216.7 2683 2450.7 1937.6 2316.4 2500.1 TRUE FALSE FALSE 2376.250702 2238.165864 2166.420178 2164.30746 2190.2673 2126.515556 2519.460046 2528.36532 2062.296715 2586.978289 0.918542963 0.86516608 0.837432686 0.836616012 0.846650824 0.8220075 0.973900731 0.977343077 0.797183619 1 11.33705223 -8.240938467 0.87991733 0.988412701 0.87831367 0 0.080055649 0.389880199 0.640452141 0.01965918 0.012748212 5.74E-09 8.240938467 -0.110099031 S(ph)FSEDVISHK ddPTM_HeLa_Curcumin_4h_R1 1 SFSEDVISHK 10 0 F6QMI7;Q03001;F8W9J4;Q03001-14;E9PHM6;A0A494C1D7;Q03001-8;Q03001-10;H0YC82 F6QMI7 DST Dystonin 1 0 S(0.853)FS(0.147)EDVISHK 132.03 0.001244 20320000 17137 14803 16429 17140 18982 19986 15305 11093 18054 14684 TRUE FALSE FALSE 15780.58837 16082.50536 17037.87319 17069.07922 18755.65205 15840.67831 15734.41711 14475.20463 16073.52137 15194.26791 1.038588267 1.05845872 1.121335578 1.123389381 1.234389979 1.042543044 1.035549538 0.952675359 1.057867445 1 13.89123954 -7.430366781 1.496931211 1.013475361 1.088420308 0.084457418 0.070481373 0.49441283 2.160804786 0.014573063 0.016151309 3.71E-08 7.430366781 0.074944947 GPSPAPASS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 GPSPAPASSPK 11 0 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 1 0 GPSPAPAS(0.225)S(0.775)PK 137.4 0.0017376 13862000 3927.6 3194.7 3910.4 3863.9 4598.5 5297.5 5139.4 10490 3585.6 3501.3 TRUE FALSE FALSE 3616.726316 3470.835633 4055.322864 3847.912206 4543.665891 4198.738785 5283.597732 13688.35271 3192.268651 3622.969914 0.998276663 0.958008406 1.119336611 1.062087816 1.254127414 1.158921792 1.458360918 3.778213188 0.881119282 1 11.82295711 -4.186699901 2.270910339 1.033672948 4.827965523 0.983648132 0.104721587 0.066899607 0.334419608 0.014714184 0.541980294 6.51E-05 4.186699901 3.794292575 up S(ph)FTGGLGQLVVPSK ddPTM_HeLa_Curcumin_4h_R1 1 SFTGGLGQLVVPSK 14 0 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 0 S(0.992)FT(0.008)GGLGQLVVPSK 187.56 2.15E-05 125280000 2540.4 1668.4 2193.9 2399.1 2086.3 2171.1 1851.8 2218.7 1502.6 1404.7 TRUE FALSE FALSE 2339.324659 1812.609062 2275.207864 2389.17316 2061.422235 1720.789387 1903.756524 2895.171416 1337.768539 1453.51322 1.609427851 1.247053715 1.56531625 1.643723033 1.418234252 1.183882859 1.309762097 1.991843883 0.920369021 1 10.50532848 -9.390302762 0.944117354 0.978628162 1.486822921 0.475644517 0.22298685 0.498355219 0.739292863 0.183678584 0.039775828 4.07E-10 9.390302762 0.508194759 S(ph)FTLDDESLK ddPTM_HeLa_Curcumin_4h_R1 1 SFTLDDESLK 10 0 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 0 S(1)FTLDDESLK 123.67 0.0022547 0 607.08 668.02 485.13 525.16 497.19 628.63 471.57 380.76 437.02 372.06 TRUE FALSE FALSE 559.0289774 725.7606722 503.1093446 522.9870271 491.261334 498.2450519 484.800985 496.8519712 389.0799994 384.9890573 1.452064589 1.885146236 1.306814661 1.358446473 1.276039733 1.294179776 1.259259129 1.290561282 1.010626126 1 8.58867363 -9.212337065 1.062292392 1.010090762 1.390734594 0.430797005 0.175855085 0.409346544 0.860064132 0.109205892 0.033874952 6.13E-10 9.212337065 0.380643832 S(ph)FVDAEVDVTR ddPTM_HeLa_Curcumin_4h_R1 3 SFVDAEVDVTR 11 0 A0A2R8YHB3;A0A1B0GUB2;A0A3B3IRP5;Q6P1J9 A0A2R8YHB3 CDC73 Parafibromin 1 0 S(1)FVDAEVDVTR;S(1)FVDAEVDVTR;S(1)FVDAEVDVTR ;; 186.76 6.92E-05 27656500 1905.86 1667.57 1979.17 1887.84 1605.5 2117.06 2131.98 1120.78 1940.3 1648.12 TRUE FALSE FALSE 1755.00917 1811.70732 2052.519781 1880.028618 1586.355461 1677.957892 2191.797621 1462.500663 1727.453944 1705.392047 1.029094262 1.062340664 1.203547175 1.102402595 0.93019987 0.983913285 1.285216279 0.857574459 1.012936554 1 10.73588772 -7.453953351 2.738591529 1.011660227 1.068154396 0.031385422 0.117176468 0.70401258 10.12167906 0.020268644 0.022475828 3.52E-08 7.453953351 0.056494169 S(ph)FVLNLGK ddPTM_HeLa_Curcumin_4h_R1 2 SFVLNLGK 8 0 P09382 P09382 LGALS1 Galectin-1 1 0 S(1)FVLNLGK;S(1)FVLNLGK ; 106.29 0.012379 21505000 4003.1 3146 4017.4 3368.8 4280.2 5880.9 4733.8 4889.3 3862.7 3600.4 TRUE FALSE FALSE 3686.250411 3417.926222 4166.288378 3354.860798 4229.16141 4661.135049 4866.617688 6380.025062 3438.971474 3725.513632 0.989460991 0.917437583 1.118312477 0.900509602 1.135188816 1.251138906 1.306294425 1.71252227 0.923086536 1 11.86322363 -3.097577607 0.617413685 0.988413102 4.266027046 0.908157067 0.071866522 2.063350257 0.184729963 0.010929103 6.698204306 0.000798771 3.097577607 3.277613944 SWSTATS(ph)PLGGERPFR ddPTM_HeLa_Curcumin_4h_R1 2 SWSTATSPLGGERPFR 16 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0;H0Y8P3;Q9UPQ0-2;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46;D6RJ93;Q6NVB9 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 SWSTAT(0.002)S(0.998)PLGGERPFR;SWSTAT(0.026)S(0.974)PLGGERPFR ; 175.66 0.00031862 82994000 5702.7 4774.1 4191.5 4840 4938.4 6746.6 6701.5 9926.4 5637.3 4712.9 TRUE FALSE FALSE 5251.325278 5186.751931 4346.840677 4819.973362 4879.512805 5347.27911 6889.526054 12952.91366 5018.902294 4876.672924 1.076825401 1.06358413 0.891353746 0.988373311 1.00058234 1.096501486 1.412751308 2.656096455 1.029165247 1 12.2516815 -4.18646024 1.894956323 1.022980719 3.38658027 0.988816016 0.052392089 0.079890848 0.251335875 0.008513279 0.352664567 6.51E-05 4.18646024 2.36359955 up S(ph)FYLALYK ddPTM_HeLa_Curcumin_4h_R1 1 SFYLALYK 8 0 H3BSS3;Q9H384;H3BQ53;Q9BQ70 H3BSS3 TCF25 Transcription factor 25 1 0 S(0.754)FY(0.246)LALYK 98.133 0.016145 4225400 1496.8 1386 1346.7 1422.6 1489.9 1769.2 1102.5 1060.8 1279.5 1208.9 TRUE FALSE FALSE 1378.326701 1505.799664 1396.609887 1416.713658 1472.133916 1402.247977 1133.433183 1384.233037 1139.142051 1250.909185 1.101859925 1.203764176 1.116475843 1.132547171 1.176851152 1.120983037 0.906087505 1.106581559 0.910651281 1 10.28876134 -3.233019841 13.93945074 1.074690706 1.090028552 0 0.098490067 0 0 0.012123625 0 0.000584763 3.233019841 0.015337846 S(ph)GAEVEAGDAAER ddPTM_HeLa_Curcumin_4h_R1 1 SGAEVEAGDAAER 13 0 A0A087WZ13;E9PAU2;Q8IY67-2;Q8IY67;K7EKR9;Q8IY67-3 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 0 S(1)GAEVEAGDAAER 188.09 4.92E-21 0 838.62 610.49 833.56 832.05 841.62 1138.2 869.28 478.78 961.6 977.64 TRUE FALSE FALSE 772.2423421 663.2580353 864.4524669 828.6071976 831.5842312 902.1244898 893.6696573 624.757818 856.1148858 1011.612917 0.763377305 0.655644095 0.854528894 0.819095114 0.822037972 0.891768457 0.883410682 0.617585845 0.846287025 1 9.982441649 -9.235397324 0.976028125 0.999716521 0.794543354 0.170266766 0.097443109 0.404447369 0.693380957 0.057250167 0.015929757 5.82E-10 9.235397324 -0.205173168 S(ph)GAKEEAGPGGAGGGGSR ddPTM_HeLa_Curcumin_4h_R1 1 SGAKEEAGPGGAGGGGSR 18 1 Q12872-2;Q12872;F5H1A5 Q12872-2 SFSWAP "Splicing factor, suppressor of white-apricot homolog" 1 0 S(1)GAKEEAGPGGAGGGGSR 55.02 0.016475 8847500 1187.5 747.6 1208.1 1122.5 1243.1 2583.8 1935.6 542.23 1365.8 1006.4 TRUE FALSE FALSE 1093.508122 812.2192128 1252.873249 1117.855392 1228.276844 2047.890755 1989.907727 707.5534309 1215.975157 1041.372325 1.050064512 0.779950833 1.203098276 1.073444498 1.179479054 1.966530803 1.910851363 0.679443283 1.167666096 1 10.02427026 -5.477287281 8.381390998 1.025938548 1.561822268 0.271876326 0.34347503 0.284974421 48.89615639 0.0450303 0.100174436 3.33E-06 5.477287281 0.53588372 S(ph)GAQASS(ph)TPLS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 3 0 S(0.909)GAQAS(0.113)S(0.489)T(0.489)PLS(0.95)PT(0.05)R 111.73 0.0069245 13258000 2653.9 2324.8 2171.1 2388.4 2492.1 4580.5 4160.7 771.69 3146 1774.9 TRUE FALSE FALSE 2443.841015 2525.745353 2251.562876 2378.517434 2462.383335 3630.452667 4277.438044 1006.974729 2800.891671 1836.577643 1.330649441 1.375245617 1.225955725 1.295081339 1.340745568 1.976748808 2.329026524 0.548288678 1.525060311 1 10.84280417 -5.46644047 5.218095049 1.196329239 1.689852756 0.067104545 0.44751268 0.245707699 14.20812295 0.059052042 0.132456695 3.42E-06 5.46644047 0.493523516 TEAELSQDLET(ph)SPTAKPQIK ddPTM_HeLa_Curcumin_4h_R1 1 TEAELSQDLETSPTAKPQIK 20 1 Q5VT06;H0Y7F7 Q5VT06 CEP350 Centrosome-associated protein 350 1 0 TEAELSQDLET(0.485)S(0.485)PT(0.03)AKPQIK 88.565 0.0011595 12365000 2968.1 2525.7 2201.1 2553.3 2597.8 3324 2272 895.67 2993.5 2370.8 TRUE FALSE FALSE 2733.171753 2744.010254 2282.674702 2542.735121 2566.822932 2634.564931 2335.746205 1168.75566 2665.120539 2453.185124 1.11413188 1.118550014 0.930494271 1.036503563 1.046322557 1.073936453 0.952127984 0.476423752 1.086391937 1 11.26044039 -4.259793626 2.894634255 1.049848691 0.374972527 0.913213317 0.052864732 0.09215705 1.079331995 0.008327876 0.14517029 5.50E-05 4.259793626 -0.674876164 down DDSLDLS(ph)PQGR ddPTM_HeLa_Curcumin_4h_R1 1 DDSLDLSPQGR 11 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 0 DDS(0.023)LDLS(0.977)PQGR 160.56 0.0003408 11321000 3047.7 3342 3074.2 3255 3156.8 3674.4 2841.7 973.3 3145.2 2854.4 TRUE FALSE FALSE 2806.471329 3630.867588 3188.132556 3241.531672 3119.157222 2912.288021 2921.430454 1270.054689 2800.179429 2953.590188 0.95018982 1.229306491 1.079409246 1.097488638 1.056056197 0.986016284 0.989111647 0.430003693 0.948059565 1 11.52825395 -4.25957184 4.869909984 1.015487243 0.398019666 0.828210267 0.082524301 0.059725272 4.143225888 0.012501004 0.124329178 5.50E-05 4.25957184 -0.617467577 down TSASEGNPYVSSTLSVPAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 TSASEGNPYVSSTLSVPASPR 21 0 G5E9V3;E9PFQ4;Q86SQ0-2;Q86SQ0-3;Q86SQ0;E9PDY7;A0A1W2PQ63 G5E9V3 PHLDB2 Pleckstrin homology-like domain family B member 2 1 0 TSASEGNPYVSSTLS(0.046)VPAS(0.954)PR;TSASEGNPYVSSTLSVPAS(1)PR;TSASEGNPYVSSTLS(0.001)VPAS(0.999)PR ;; 335.36 4.88E-159 235692900 8054.6 6371.9 6687.6 7004.2 7240.1 9658.7 6341.2 1776.48 7984.7 7502.3 TRUE FALSE FALSE 7417.069911 6922.658643 6935.448339 6975.218476 7153.766536 7655.376744 6519.117006 2318.120574 7108.798387 7763.004367 0.95543807 0.891749936 0.893397454 0.898520489 0.921520355 0.986135829 0.839767273 0.298611268 0.915727733 1 12.92239938 -4.259536635 2.826891853 0.956545738 0.177156268 0.952497956 0.041962119 0.070193252 0.766422245 0.006992323 0.125811111 5.50E-05 4.259536635 -0.77938947 down S(ph)GASEANLIVAK ddPTM_HeLa_Curcumin_4h_R1 2 SGASEANLIVAK 12 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 S(0.934)GAS(0.066)EANLIVAK;S(0.997)GAS(0.003)EANLIVAK ; 155.56 0.00033787 33064000 2864.5 1696.6 2688.7 3443.7 3173.7 5531.6 4754.8 474.2 3600 2179.5 TRUE FALSE FALSE 2637.771802 1843.246544 2788.345587 3429.450882 3135.8557 4384.283806 4888.206891 618.7813971 3205.089007 2255.237463 1.169620426 0.817318165 1.236386692 1.520660657 1.390476946 1.944045307 2.167490995 0.274375274 1.421175845 1 11.13906363 -6.39909958 3.53895161 1.061329845 1.522506613 0.0973651 0.487645396 0.317680653 7.282651523 0.069214431 0.107914254 3.99E-07 6.39909958 0.461176768 S(ph)GDAMGMNMISK ddPTM_HeLa_Curcumin_4h_R1 1 SGDAMGMNMISK 12 0 P04035-2;P04035;P04035-3 P04035-2 HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 0 S(0.999)GDAMGMNMIS(0.001)K 44.543 0.019433 4539400 2104.9 3056.2 2105.8 2113.6 2674.8 4303.7 2733.3 1961.9 2247.6 2402.4 TRUE FALSE FALSE 1938.294944 3320.36431 2183.8428 2104.854483 2642.904757 3411.064107 2809.989042 2560.074279 2001.043903 2485.883221 0.779720836 1.335687969 0.878497744 0.846722994 1.06316529 1.372173913 1.130378538 1.029844949 0.804962955 1 11.27954281 -5.53406003 7.719346143 0.926603187 1.180325313 0.286441019 0.167264434 0.127682021 47.69430462 0.024790056 0.050853685 2.92E-06 5.53406003 0.253722126 S(ph)GDETPGSEVPGDK ddPTM_HeLa_Curcumin_4h_R1 3 SGDETPGSEVPGDK 14 0 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 0 S(0.996)GDET(0.004)PGSEVPGDK;S(0.998)GDET(0.002)PGSEVPGDK;S(1)GDETPGSEVPGDK ;; 241.41 1.23E-28 208696500 5381.6 5874.3 6361.8 5290.9 7302.5 5883.5 4910.2 5483.3 4051.78 4212.99 TRUE FALSE FALSE 4955.640681 6382.048317 6597.573904 5269.007658 7215.422457 4663.195779 5047.966997 7155.132928 3607.309871 4359.391089 1.136773595 1.463977007 1.513416385 1.208656794 1.655144563 1.069689708 1.157952314 1.641314758 0.827480214 1 12.08991092 -7.44509984 3.402621191 1.056102568 1.373857035 0.444964275 0.200729192 0.186112312 3.994836116 0.032558758 0.036324543 3.59E-08 7.44509984 0.317754467 S(ph)GEGEVSGLMR ddPTM_HeLa_Curcumin_4h_R1 2 SGEGEVSGLMR 11 0 Q13263-2;Q13263;M0R0K9 Q13263-2 TRIM28 Transcription intermediary factor 1-beta 1 0 S(1)GEGEVSGLMR;S(1)GEGEVSGLMR ; 174.23 0.00021547 174893000 11248.9 10323.8 14686.4 14391.1 12896.3 15590.5 13532.7 17770 15888 14010.2 TRUE FALSE FALSE 10358.5377 11216.14327 15230.6909 14331.55344 12742.52005 12356.85456 13912.39114 23187.9912 14145.12615 14497.05341 0.714527111 0.773684345 1.050605973 0.988583889 0.878973105 0.852370079 0.959670269 1.599496846 0.975724222 1 13.82347208 -4.259725015 3.559197817 0.878673434 1.68538204 0.802442724 0.102248436 0.110931458 2.468916573 0.017715654 0.238935285 5.50E-05 4.259725015 0.806708606 S(ph)GELQGGPDDNLIEGGGTK ddPTM_HeLa_Curcumin_4h_R1 2 SGELQGGPDDNLIEGGGTK 19 0 Q96A65 Q96A65 EXOC4 Exocyst complex component 4 1 0 S(1)GELQGGPDDNLIEGGGTK;S(1)GELQGGPDDNLIEGGGTK ; 211.17 4.24E-14 8352100 2232.58 1334.67 2124.36 1831.68 1927.09 2570.9 2097.8 1132.96 1778.68 1792.34 TRUE FALSE FALSE 2055.868937 1450.032928 2203.09065 1824.100993 1904.11071 2037.66636 2156.658622 1478.394288 1583.563254 1854.623682 1.108510022 0.781847521 1.18789093 0.983542382 1.026683057 1.09869532 1.162855108 0.797139767 0.85384613 1 10.85691077 -4.24317926 24.2577619 1.045939707 0.797139447 0.210308588 0.123910006 2323.267313 3086286.743 0.013917061 0.58869511 5.71E-05 4.24317926 -0.248800261 S(ph)GEQIFTQDVRPEQLLEGK ddPTM_HeLa_Curcumin_4h_R1 1 SGEQIFTQDVRPEQLLEGK 19 1 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 0 S(0.998)GEQIFT(0.002)QDVRPEQLLEGK 68.569 0.004906 4208000 1292.4 974.56 1123.5 1179.4 883.02 767.53 858.74 1820.4 788.77 775.11 TRUE FALSE FALSE 1190.105176 1058.796624 1165.137898 1174.519955 872.4905632 608.3356262 882.8339332 2375.43158 702.2439044 802.0450148 1.483838381 1.320121196 1.452708859 1.464406528 1.087832412 0.758480652 1.100728659 2.961718527 0.875566697 1 9.6475394 -4.259003182 24.98728861 1.222424579 2.961719141 0.824871626 0.246458927 73.3136207 751906.7407 0.036661968 0.330650668 5.51E-05 4.259003182 1.739294562 S(ph)GEQIT(ph)SSPVSPK ddPTM_HeLa_Curcumin_4h_R1 1 SGEQITSSPVSPK 13 0 A0A087WZV0;O43314-2;O43314;A0A087WWN8 A0A087WZV0 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 2 0 S(0.993)GEQIT(0.507)S(0.363)S(0.138)PVSPK 112.02 0.016279 8308500 3666 3120.4 3518.8 3015.4 3141.3 3540.4 2712.9 2545.6 3309.7 3445 TRUE FALSE FALSE 3375.832232 3390.113472 3649.209823 3002.923074 3103.842049 2806.081131 2789.016673 3321.741721 2946.63419 3564.713494 0.947013621 0.9510199 1.02370354 0.842402364 0.870712907 0.787182795 0.782395746 0.931839747 0.826611787 1 11.79957041 -6.246677536 23.72780301 0.975487166 0.837993983 0.373148329 0.064860541 176.2578415 283311.6939 0.006760634 0.011174736 5.67E-07 6.246677536 -0.137493183 S(ph)GEQITSSPVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SGEQITSSPVSPK 13 0 A0A087WZV0;O43314-2;O43314;A0A087WWN8 A0A087WZV0 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 2 0 S(1)GEQIT(0.01)S(0.013)S(0.03)PVS(0.948)PK 142.88 0.0020688 21409000 3034.3 2306.6 2339.9 2557.5 2417.7 2556.1 2556.5 2263.3 2370.2 2062.6 TRUE FALSE FALSE 2794.131953 2505.972226 2426.618752 2546.917743 2388.870507 2025.936047 2628.22851 2953.369751 2110.19499 2134.275196 1.309171356 1.174156093 1.136975567 1.193340834 1.119288886 0.949238435 1.231438436 1.383781134 0.988717384 1 11.0595305 -9.588283225 1.392594909 1.000498697 1.194629528 0.326887896 0.109764792 0.45815628 1.600185514 0.082267111 0.019339535 2.58E-10 9.588283225 0.194130831 S(ph)GEQITSSPVSPK ddPTM_HeLa_Curcumin_4h_R1 2 SGEQITSSPVSPK 13 0 A0A087WZV0;O43314-2;O43314;A0A087WWN8 A0A087WZV0 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 1 0 S(1)GEQITSSPVSPK;S(0.598)GEQIT(0.289)S(0.026)S(0.087)PVSPK ; 162.64 0.00020719 32710000 6206 4612.6 6301.2 5667.4 5948.3 5805.8 5225 3822.2 5701.2 5911.9 TRUE FALSE FALSE 5714.788551 5011.292591 6534.728015 5643.9498 5877.370407 4601.611635 5371.599438 4987.571185 5075.792624 6117.338085 0.93419531 0.81919497 1.068230646 0.922615314 0.960772533 0.752224509 0.878094257 0.815317237 0.829738777 1 12.5786883 -1 0.18858087 0.997285623 0.141949375 0.073648531 0.088522198 43.51776 0.484615355 0.080447178 10.88230932 0.1 1 -0.855336248 S(ph)GEVTLTK ddPTM_HeLa_Curcumin_4h_R1 2 SGEVTLTK 8 0 A0A0G2JIS2;A2ABF8;A0A0G2JIR1;A2ABF9;A0A0G2JK64;Q96KQ7-2;Q96KQ7 A0A0G2JIS2 EHMT2 Histone-lysine N-methyltransferase EHMT2 1 0 S(0.998)GEVT(0.002)LTK;S(1)GEVTLTK ; 119.22 0.0085171 23341300 4242.9 4082.5 3998.6 4503 4749.2 6994.8 5931.4 3795.7 5551.4 4301 TRUE FALSE FALSE 3907.069988 4435.373109 4146.791634 4484.367779 4692.568892 5543.999632 6097.81912 4952.991457 4942.425309 4450.45943 0.877902619 0.996610165 0.93176709 1.007619067 1.054401004 1.245714003 1.370154973 1.112916888 1.110542717 1 12.11973856 -5.461719739 2.038674358 0.947246834 1.260314877 0.620552809 0.08599196 0.111338405 0.905133033 0.010752313 0.028583089 3.45E-06 5.461719739 0.313068043 S(ph)GGDGGDEVEGSGVGAGEGETVQHFPLAR ddPTM_HeLa_Curcumin_4h_R1 1 SGGDGGDEVEGSGVGAGEGETVQHFPLAR 29 0 Q96DT7-3;Q96DT7-2;Q96DT7 Q96DT7-3 ZBTB10 Zinc finger and BTB domain-containing protein 10 1 0 S(1)GGDGGDEVEGSGVGAGEGETVQHFPLAR 146.49 2.17E-12 3320600 1079.5 1049.6 1115.5 984.52 1411.3 1392.5 1091.1 1318.8 1028.9 1020.5 TRUE FALSE FALSE 994.0564359 1140.322747 1156.841411 980.4463171 1394.471169 1103.679803 1121.713329 1720.896049 916.0322442 1055.962299 0.941374931 1.07988964 1.095532873 0.9284861 1.320569087 1.045188644 1.062266456 1.629694593 0.867485747 1 10.04434261 -1.489907059 1.002932544 1.004028406 200 0.673095445 0.121642184 222.8500299 0.87577855 0.017323513 101149.5107 0.032366291 1.489907059 198.9959716 S(ph)GGGAGSNGSVLDPAER ddPTM_HeLa_Curcumin_4h_R1 2 SGGGAGSNGSVLDPAER 17 0 Q15149-3;Q15149-2;H0YDN1;E9PMV1 Q15149-3 PLEC Plectin 1 0 S(1)GGGAGSNGSVLDPAER;S(1)GGGAGSNGSVLDPAER ; 127.37 0.00033859 121901000 1598.57 1314.9 1393.78 1379.37 1426.68 1847.07 1681.45 1387.37 1798.56 1218.48 TRUE FALSE FALSE 1472.041498 1428.554097 1445.434713 1373.662532 1409.667773 1463.966861 1728.626962 1810.372726 1601.262468 1260.822089 1.167525149 1.133033843 1.146422422 1.089497514 1.11805447 1.161120886 1.371031628 1.435866917 1.270014605 1 10.300149 -1 0.42843989 1.075719486 8.797333243 0.591137739 0.080241898 25.50628327 0.287175472 0.015812146 171.4540455 0.1 1 7.721613757 S(ph)GGGDLTLGLEPSEEEAPR ddPTM_HeLa_Curcumin_4h_R1 2 SGGGDLTLGLEPSEEEAPR 19 0 B4DTR1;P04626-3;P04626-2;P04626-5;P04626-4;P04626 B4DTR1 ERBB2 Receptor protein-tyrosine kinase;Receptor tyrosine-protein kinase erbB-2 1 0 S(1)GGGDLTLGLEPSEEEAPR;S(1)GGGDLTLGLEPSEEEAPR ; 180.31 3.12E-07 20258800 2271.48 2226.83 2142.11 3116.3 2139.61 3849.3 1083.45 284.1758 3390.7 2058.47 TRUE FALSE FALSE 2091.689961 2419.307263 2221.498481 3103.405576 2114.096548 3050.911789 1113.848691 370.8196932 3018.748693 2130.001679 0.982013292 1.13582411 1.042956211 1.456996774 0.992532808 1.432351824 0.522933245 0.174093615 1.41725179 1 11.05663885 -4.572999517 5.664975424 1.061637784 0.25157206 0.699983607 0.211981958 0.062101817 4.374169286 0.025203662 0.101120296 2.67E-05 4.572999517 -0.810065723 S(ph)GGNEVSIEER ddPTM_HeLa_Curcumin_4h_R1 2 SGGNEVSIEER 11 0 Q15061 Q15061 WDR43 WD repeat-containing protein 43 1 0 S(1)GGNEVSIEER;S(1)GGNEVSIEER ; 188.63 4.68E-05 67259000 2285.5 1868.38 1388.71 1976.19 1596.12 2575.7 2135.24 1123.29 2088.6 1679.17 TRUE FALSE FALSE 2104.600263 2029.874442 1440.176814 1968.013049 1577.087311 2041.470786 2195.149088 1465.77595 1859.485805 1737.521033 1.211266065 1.168258918 0.828868709 1.13265567 0.907665163 1.174932992 1.263379865 0.843601846 1.070194703 1 10.76281473 S(ph)GGSGGCSGAGGASNCGTGSGR ddPTM_HeLa_Curcumin_4h_R1 1 SGGSGGCSGAGGASNCGTGSGR 22 0 E9PL01;A0A087WUC6;E9PI68;Q15005 E9PL01 SPCS2 Signal peptidase complex subunit 2 1 0 S(0.833)GGS(0.167)GGCS(0.001)GAGGASNCGTGSGR 125.03 1.02E-05 773600 0 0 0 0 0 70.866 0 0 98.475 123.77 TRUE FALSE FALSE 0 0 0 0 0 56.16759278 0 0 87.67253887 128.0709983 0 0 0 0 0 0.438566057 0 0 0.684562001 1 7.000800004 -9.18310649 0.776018579 1.045828446 0.053011486 0.786641494 0.160687911 0.194018064 0.196243074 0.119306041 0.028507567 6.56E-10 9.18310649 -0.992816961 S(ph)GHFDVTTVASIK ddPTM_HeLa_Curcumin_4h_R1 1 SGHFDVTTVASIK 13 0 Q8TDM6-4;Q8TDM6;A0A0A0MSL1;Q8TDM6-2;Q8TDM6-5 Q8TDM6-4 DLG5 Disks large homolog 5 1 0 S(0.998)GHFDVT(0.001)T(0.001)VASIK 95.264 0.0094706 17555000 703.2 474.92 525.25 553.3 577.19 583.38 348.65 257.44 548.61 277.99 TRUE FALSE FALSE 647.540978 515.9699686 544.7162271 551.0105912 570.3073862 462.380412 358.4321807 335.9322709 488.4288556 287.6501318 2.251140905 1.793741464 1.893676264 1.915558278 1.982642534 1.607440292 1.246069934 1.167850224 1.697996286 1 8.168171321 -2.542784859 9.819275553 1.63720241 1.470629383 0 0.380512725 0 0 0.068290019 0 0.002865597 2.542784859 -0.166573028 S(ph)GKDSEAWVPDSEER ddPTM_HeLa_Curcumin_4h_R1 2 SGKDSEAWVPDSEER 15 1 M0QXS4;Q96F63 M0QXS4 CCDC97 Coiled-coil domain-containing protein 97 1 0 S(0.961)GKDS(0.039)EAWVPDSEER;S(0.997)GKDS(0.003)EAWVPDSEER ; 76.526 0.0086954 14195700 3546.7 3088.7 3360.4 2864.78 3725.3 3222.1 2903.1 3155 2858.2 2932.2 TRUE FALSE FALSE 3265.974953 3355.673465 3484.93938 2852.926299 3680.878231 2553.800139 2984.553173 4116.944976 2544.662611 3034.093732 1.0764252 1.105988727 1.148593184 0.940289441 1.213172221 0.841701136 0.983672041 1.35689446 0.838689518 1 11.56704994 -9.07646957 0.89905311 1.000874023 1.0739094 0.114997344 0.14614492 1.72608579 2.572267293 0.079439936 0.024903856 8.39E-10 9.07646957 0.073035377 S(ph)GLQLSLEQGTGENSFR ddPTM_HeLa_Curcumin_4h_R1 1 SGLQLSLEQGTGENSFR 17 0 P23497;E9PHV6;P23497-7;P23497-6;P23497-2;P23497-3;P23497-4;P23497-5;C9JBL0 P23497 SP100 Nuclear autoantigen Sp-100 1 0 S(0.993)GLQLS(0.007)LEQGTGENSFR 129.05 0.00034105 3401200 2192.8 2141.3 2650.3 3027.2 2454.4 2922.1 2830 2576.9 2797.1 2997 TRUE FALSE FALSE 2019.237566 2326.384431 2748.522449 3014.674249 2425.132883 2316.023521 2909.402183 3362.584947 2490.265128 3101.145527 0.651126349 0.750169384 0.886292638 0.972116343 0.782011957 0.74682839 0.938170156 1.084304144 0.803014598 1 11.59858551 -4.448309296 3.485873323 0.830789662 1.07810502 0.391252924 0.100854988 0.284676342 6.104203568 0.019528009 0.13775232 3.56E-05 4.448309296 0.247315359 S(ph)GPGPPELDSEQPSR ddPTM_HeLa_Curcumin_4h_R1 2 SGPGPPELDSEQPSR 15 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 0 S(1)GPGPPELDSEQPSR;S(1)GPGPPELDSEQPSR ; 118.31 0.0014507 7184300 2604.23 1934.84 2233.58 2845.64 2859.52 2634.4 2029.61 1816.22 3010.1 2716.44 TRUE FALSE FALSE 2398.102448 2102.078948 2316.35844 2833.865496 2825.422092 2087.995744 2086.555394 2369.977117 2679.899561 2810.836088 0.853163391 0.747848285 0.824081649 1.008193081 1.005189205 0.74283796 0.742325532 0.843157354 0.953417231 1 11.45678361 -9.0081842 0.769028256 1.002654738 0.84617111 0.235249051 0.092422535 0.768107553 0.817635499 0.070276029 0.020662814 9.81E-10 9.0081842 -0.156483628 S(ph)GPSPLSSPNGK ddPTM_HeLa_Curcumin_4h_R1 2 SGPSPLSSPNGK 12 0 H0YM23;O75179-6;O75179-7;O75179-2;O75179;O75179-4 H0YM23 ANKRD17 Ankyrin repeat domain-containing protein 17 1 0 S(0.868)GPS(0.127)PLS(0.004)SPNGK;S(0.873)GPS(0.127)PLSSPNGK ; 201.38 8.26E-09 89101000 6018.3 5072.5 5216.1 5406.2 5395.6 6792.9 4873.1 3172.9 5565.9 5769.8 TRUE FALSE FALSE 5541.945205 5510.944297 5409.413255 5383.830577 5331.260994 5383.975968 5009.826071 4140.302604 4955.334695 5970.300121 0.928252365 0.923059844 0.906053824 0.901768834 0.892963651 0.901793186 0.839124662 0.693483162 0.829997587 1 12.54358774 -2.159223257 0.288601432 0.977333168 2.36E-33 0.492085188 0.054885944 7.691190878 0.178784027 0.014641978 3.39926921 0.006930694 2.159223257 -0.977333168 S(ph)GPTDDGEEEMEEDTVTNGS ddPTM_HeLa_Curcumin_4h_R1 1 SGPTDDGEEEMEEDTVTNGS 20 0 P09661 P09661 SNRPA1 U2 small nuclear ribonucleoprotein A 1 0 S(0.968)GPT(0.032)DDGEEEMEEDTVTNGS 125.39 9.49E-05 6826300 1353.3 937.32 1199.2 1204 1313.3 1730.8 1301.6 1212.8 1666.9 1239.5 TRUE FALSE FALSE 1246.184877 1018.337764 1243.643407 1199.018167 1297.639755 1371.81257 1338.119393 1582.577137 1484.04524 1282.572533 0.971629163 0.793980643 0.969647622 0.934854081 1.011747657 1.06957894 1.043308943 1.23390849 1.157084845 1 10.3248247 -3.364130969 0.783840641 0.967526772 2.040023935 0.434944315 0.08610446 4.526785025 0.717334667 0.010515036 5.928108672 0.000432383 3.364130969 1.072497163 S(ph)GQKPVLDVHAELDR ddPTM_HeLa_Curcumin_4h_R1 1 SGQKPVLDVHAELDR 15 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 0 S(1)GQKPVLDVHAELDR 79.022 0.0062836 4384300 2758.9 2578 2016.5 2867.9 2413.1 5075.8 5242 1871.7 2482.6 2687.5 TRUE FALSE FALSE 2540.530154 2800.830833 2091.233264 2856.03339 2384.325359 4023.021864 5389.076412 2442.372714 2210.264991 2780.890425 0.913567155 1.007170512 0.752001318 1.027021189 0.857396371 1.446666804 1.937895993 0.878270029 0.794804776 1 11.44133118 -5.252934399 22.42795829 0.945407115 1.472639714 0.450750443 0.255483041 90.68800053 239143.5106 0.031186559 0.077867939 5.59E-06 5.252934399 0.527232599 S(ph)GS(ph)MDPSGAHPS(ph)VRQT(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 SGSMDPSGAHPSVRQTPSR 19 1 Q07666-2;Q07666;Q07666-3 Q07666-2 KHDRBS1 "KH domain-containing, RNA-binding, signal transduction-associated protein 1" 4 0 S(0.997)GS(0.998)MDPS(0.021)GAHPS(0.93)VRQT(0.629)PS(0.425)R 44.089 0.0091906 0 614.61 1553.2 711.67 1249.6 711.93 727.06 600.35 636.27 1751.5 1590.5 TRUE FALSE FALSE 565.96297 1687.451687 738.0451162 1244.429486 703.4406997 576.2595603 617.1942052 830.265794 1559.364832 1645.769757 0.343889519 1.025326708 0.448449799 0.756138264 0.427423518 0.350145917 0.375018561 0.50448478 0.947498777 1 10.6845468 -9.478390828 1.032842027 1.020971554 0.516135518 0.435435426 0.202085705 0.44303484 0.785951 0.174885101 0.036168718 3.32E-10 9.478390828 -0.504836037 S(ph)GSESEEAELSLSLAR ddPTM_HeLa_Curcumin_4h_R1 1 SGSESEEAELSLSLAR 16 0 Q8IV50 Q8IV50 LYSMD2 LysM and putative peptidoglycan-binding domain-containing protein 2 1 0 S(0.72)GS(0.28)ESEEAELSLSLAR 203.05 2.77E-10 4583200 1744.6 1186.1 1742.1 1784.4 1343.8 2223 1739.4 1871.2 2047.6 1889.7 TRUE FALSE FALSE 1606.513069 1288.621199 1806.663759 1777.016626 1327.776063 1761.924742 1788.202883 2441.720266 1822.983403 1955.366934 0.821591611 0.659017587 0.923951268 0.90878934 0.679041892 0.901071155 0.914510137 1.248727399 0.932297346 1 10.93322365 -4.249677737 3.42088646 0.878613836 1.300938635 0.544051528 0.106024934 0.230099047 4.423081605 0.016628779 0.255680637 5.63E-05 4.249677737 0.4223248 S(ph)GSFRDGFEEESWEK ddPTM_HeLa_Curcumin_4h_R1 1 SGSFRDGFEEESWEK 15 1 A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-11;Q8IVL1 A0A0A0MTE8 NAV2 Neuron navigator 2 1 0 S(0.708)GS(0.292)FRDGFEEESWEK 60.631 0.019791 3944500 1258 744.53 872.88 1108.9 950.32 1563.3 1101.1 468.22 1230.3 767.38 TRUE FALSE FALSE 1158.427973 808.8838556 905.2297007 1104.311666 938.9880547 1239.053958 1131.993903 610.9781226 1095.339168 794.0463979 1.458892044 1.018685883 1.140021166 1.390739469 1.182535501 1.560430173 1.42560171 0.769448894 1.379439754 1 9.633079499 -6.28216975 24.10686504 1.198974185 1.286379734 0.01562634 0.236447386 1899.233128 2208570.133 0.039370916 0.060190703 5.22E-07 6.28216975 0.087405549 S(ph)GSGISVISST(ph)SVDQR ddPTM_HeLa_Curcumin_4h_R1 1 SGSGISVISSTSVDQR 16 0 Q15811;Q15811-3;F8W7U0;Q15811-7;Q15811-8;Q15811-9;Q15811-2;Q15811-4;Q15811-10;Q15811-11;Q15811-12;Q15811-6;Q15811-5;Q15811-13;A8CTZ0;C9JQZ7;D6PAW0 Q15811 ITSN1 Intersectin-1 2 0 S(0.929)GS(0.07)GIS(0.064)VIS(0.05)S(0.024)T(0.715)S(0.147)VDQR 106.28 0.0085969 5015000 3290.3 3192.3 3787.9 3426.4 3848.3 4185.5 3324.3 2891 3631.4 3004.3 TRUE FALSE FALSE 3029.869283 3468.228187 3928.282906 3412.222465 3802.411536 3317.38012 3417.570911 3772.452591 3233.044505 3108.699201 0.974642153 1.115652549 1.26364201 1.097636742 1.223151965 1.067128051 1.09935722 1.213514833 1.039999143 1 11.60209531 -7.172676007 4.44987095 0.988023725 1.155873903 0.557994272 0.061143043 0.099968045 3.517530052 0.009370655 0.011502038 6.72E-08 7.172676007 0.167850178 S(ph)GSIVELIAGGGSSCSPVLSR ddPTM_HeLa_Curcumin_4h_R1 1 SGSIVELIAGGGSSCSPVLSR 21 0 P42858 P42858 HTT Huntingtin 1 0 S(0.617)GS(0.383)IVELIAGGGSSCSPVLSR 94.384 0.0015233 0 243.5 401.72 320.32 401.73 437.56 487.65 286.26 733.72 492.97 472.92 TRUE FALSE FALSE 224.2267181 436.4428868 332.191341 400.0677477 432.3423828 386.5058931 294.2916852 957.4278504 438.8924244 489.3539348 0.458209697 0.891875707 0.678836558 0.817542722 0.883496284 0.789828927 0.601388206 1.956514053 0.896881364 1 8.93473449 -4.256958427 24.91321697 0.754970994 1.956514559 0.839033828 0.154279355 160.5334421 892500.6045 0.027979986 0.296896162 5.53E-05 4.256958427 1.201543565 S(ph)GSLGQPSPSAQR ddPTM_HeLa_Curcumin_4h_R1 1 SGSLGQPSPSAQR 13 0 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0;H0Y4U1 A0A087WWW7 TNS1 Tensin-1 1 0 S(0.727)GS(0.001)LGQPS(0.03)PS(0.242)AQR 128.95 0.0017225 16402000 2398.1 2058.4 1683.3 1669.5 1637.2 2156 1665.1 1112.4 2390.6 2023.1 TRUE FALSE FALSE 2208.287855 2236.318924 1745.684579 1662.592051 1617.677459 1708.821297 1711.818225 1451.565639 2128.357161 2093.402574 1.054879688 1.068269883 0.833898171 0.794205602 0.772750296 0.816288906 0.817720512 0.69340014 1.016697499 1 11.03163406 -6.668321323 4.585226355 1.029744213 0.78572631 0.910610534 0.038100591 0.046620226 1.732417758 0.006403434 0.009091015 2.15E-07 6.668321323 -0.244017902 S(ph)GSMDPSGAHPSVR ddPTM_HeLa_Curcumin_4h_R1 1 SGSMDPSGAHPSVR 14 0 Q07666-2;Q07666;Q07666-3 Q07666-2 KHDRBS1 "KH domain-containing, RNA-binding, signal transduction-associated protein 1" 1 0 S(0.521)GS(0.442)MDPS(0.016)GAHPS(0.02)VR 70.235 0.019823 8979800 1838.5 1648.3 1295.8 1801.6 2383.2 5060.5 2019.8 883.22 2834.6 1830.6 TRUE FALSE FALSE 1692.980785 1790.771707 1343.823488 1794.145457 2354.781897 4010.895256 2076.470152 1152.509712 2523.651472 1894.213214 0.893764637 0.94539078 0.709436234 0.947171862 1.243145111 2.117446562 1.096217753 0.608437162 1.332295358 1 10.88738302 -5.729958053 5.218677063 0.927558904 1.320242827 0.118357081 0.375875817 0.226096898 15.50754608 0.051271463 0.101818571 1.86E-06 5.729958053 0.392683923 LAS(ph)VSADAEVAR ddPTM_HeLa_Curcumin_4h_R1 1 LASVSADAEVAR 12 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 LAS(0.593)VS(0.407)ADAEVAR 109.95 0.0055932 21997000 875.52 795.84 1136 1133.5 1162.8 1613.2 2363.5 4254.3 1093.4 1266.4 TRUE FALSE FALSE 806.2216682 864.6288634 1178.101159 1128.809877 1148.934369 1278.604135 2429.813449 5551.416486 973.4567556 1310.407306 0.615245096 0.659816883 0.899034334 0.861419096 0.876776529 0.975730317 1.854242905 4.236405323 0.742865788 1 10.35579959 -4.182813899 1.641640075 0.813058627 5.964673937 0.988733316 0.110504799 0.118702639 0.260458594 0.022418373 1.024592338 6.56E-05 4.182813899 5.151615309 up S(ph)GSS(ph)SPDSEITELKFPSINHD ddPTM_HeLa_Curcumin_4h_R1 1 SGSSSPDSEITELKFPSINHD 21 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 2 0 S(0.515)GS(0.515)S(0.34)S(0.34)PDS(0.281)EIT(0.007)ELKFPSINHD 61.684 0.0071183 23605000 890.32 794.07 921.69 717.68 1534.8 2360.6 1662.5 1428.9 1497.8 972.66 TRUE FALSE FALSE 819.8502325 862.7058725 955.8486422 714.7104303 1516.498512 1870.984951 1709.145276 1864.565032 1333.495087 1006.459863 0.814588105 0.857168681 0.949713623 0.710123132 1.506765017 1.85897622 1.698175297 1.852597507 1.324936182 1 9.975073924 -5.607587461 4.197891032 0.897088851 1.780561363 0.851751231 0.163077094 0.034538565 1.146461042 0.015001883 0.031159807 2.47E-06 5.607587461 0.883472512 S(ph)GSSPGLR ddPTM_HeLa_Curcumin_4h_R1 1 SGSSPGLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.965)GS(0.018)S(0.018)PGLR 100.02 0.015043 2263000 1103.2 1679.6 1139.6 1173.7 1132.8 1402.9 1239.5 642.22 1028.8 1146.6 TRUE FALSE FALSE 1015.880556 1824.77714 1181.834578 1168.84354 1119.2921 1111.922726 1274.277034 838.0299216 915.9432139 1186.444265 0.856239594 1.538021797 0.996114705 0.985165149 0.943400489 0.937189179 1.074030253 0.70633737 0.772006946 1 10.21242861 -4.249747113 23.73049459 0.987232811 0.706337022 0.171554647 0.194693481 1244.282185 2525283.742 0.025629041 0.523966137 5.63E-05 4.249747113 -0.280895789 S(ph)GSSPGLRDGSGT(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 SGSSPGLRDGSGTPSR 16 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(0.481)GS(0.037)S(0.481)PGLRDGS(0.076)GT(0.724)PS(0.2)R 121.51 0.00042496 0 2223.5 1829 1543.3 1903.8 1267.1 2548.1 1387 958.84 2534.5 2070.5 TRUE FALSE FALSE 2047.507629 1987.09061 1600.496056 1895.92258 1251.99066 2019.595337 1425.915487 1251.185902 2256.471691 2142.449721 0.955685265 0.927485294 0.747040194 0.884932123 0.584373415 0.942657052 0.665553769 0.58399779 1.053220372 1 11.06504563 -4.460171252 0.239549808 1.031029433 0.324023774 0.6088537 0.103583284 4.72898672 0.241740484 0.078958105 0.992866764 3.47E-05 4.460171252 -0.707005659 S(ph)GSSS(ph)PDSEITELK ddPTM_HeLa_Curcumin_4h_R1 1 SGSSSPDSEITELK 14 0 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 2 0 S(0.769)GS(0.23)S(0.004)S(0.983)PDS(0.015)EITELK 219.84 1.08E-13 12621000 6100.5 5205.5 6197.2 5417.9 7727.1 6235.4 6893.9 6355.8 4726.9 4455.9 TRUE FALSE FALSE 5617.638988 5655.440225 6426.873684 5395.482165 7634.959379 4942.107753 7087.32428 8293.654161 4208.370896 4610.742193 1.218380632 1.226579147 1.393891355 1.170198189 1.655906806 1.07186816 1.537133065 1.798767707 0.912731773 1 12.17078329 -1 0.142830878 0.929523821 3.442460012 0.589012735 0.17689556 38.34445599 0.359689901 0.413789678 19.83470031 0.1 1 2.512936191 S(ph)GSSSSSSGTPASQLYPQSR ddPTM_HeLa_Curcumin_4h_R1 1 SGSSSSSSGTPASQLYPQSR 20 0 O15066-2;O15066 O15066-2 KIF3B "Kinesin-like protein KIF3B;Kinesin-like protein KIF3B, N-terminally processed" 1 0 S(0.989)GS(0.011)SSSSSGTPASQLYPQSR 220.89 5.66E-19 7790300 1153.3 1153.3 1146.4 1412 1246.5 1715.5 1416.8 828.42 1689.3 1182.6 TRUE FALSE FALSE 1062.015088 1252.986113 1188.886592 1406.157518 1231.636302 1359.685962 1456.551595 1081.001444 1503.988016 1223.695262 0.86787546 1.023936393 0.971554462 1.149107594 1.006489393 1.111131182 1.190289478 0.883391052 1.229054376 1 10.25702861 -6.660739481 1.964473692 0.939588698 1.072405886 0 0.127243549 0.298193632 2.347328156 0.014943415 0.022305346 2.18E-07 6.660739481 0.132817188 IIGEDS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 IIGEDSPSR 9 0 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 IIGEDS(0.966)PS(0.034)R 131.42 0.003696 54853000 3370.3 3301.5 3288.4 3320.4 3871.3 3733.1 3011.6 1045.3 3207.9 2824.7 TRUE FALSE FALSE 3103.537199 3586.866949 3410.270997 3306.661065 3825.137276 2958.812979 3096.097391 1364.007158 2856.001396 2922.858115 1.061815893 1.227177922 1.166758995 1.131310838 1.308697558 1.012301269 1.059270505 0.46666896 0.977126252 1 11.51316408 -4.259511737 5.283063221 1.078794389 0.440509776 0.771890027 0.10326768 0.063305287 6.145641608 0.015466434 0.145840778 5.50E-05 4.259511737 -0.638284613 down S(ph)GSYSYLEER ddPTM_HeLa_Curcumin_4h_R1 2 SGSYSYLEER 10 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;H0YIM2;H0YIS3;A0A0U1RQZ1 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 S(0.986)GS(0.014)YSYLEER;S(0.637)GS(0.363)YSYLEER ; 108.98 0.0080439 29818100 3408.5 1952.97 2292.2 2252.1 2748.5 4165.2 2270.69 2580.87 2766.1 2115.5 TRUE FALSE FALSE 3138.713628 2121.776025 2377.150948 2242.781407 2715.725933 3301.290569 2334.39945 3367.765382 2462.66575 2189.013468 1.433848478 0.969284135 1.085946242 1.024562635 1.240616366 1.50811798 1.066416212 1.538485456 1.125011695 1 11.09606512 -9.666486188 1.521306755 1.000151563 1.250750477 0.091942309 0.196754953 0.565521567 2.357878227 0.141522096 0.031805082 2.16E-10 9.666486188 0.250598914 S(ph)GT(ph)RCRS(ph)RS(ph)WIQK ddPTM_HeLa_Curcumin_4h_R1 1 SGTRCRSRSWIQK 13 3 Q86VH2-4;Q86VH2-3;Q86VH2-2;Q86VH2 Q86VH2-4 KIF27 Kinesin-like protein KIF27 4 0 S(1)GT(1)RCRS(1)RS(1)WIQK 47.187 0.0094242 0 1497.9 917.92 1353 1187.9 1558.5 1695.9 1088.3 468.77 1303.8 1433 TRUE FALSE FALSE 1379.339634 997.2609146 1403.14337 1182.984785 1539.915905 1344.151223 1118.834769 611.695815 1160.776402 1482.796643 0.930228458 0.672554068 0.946281728 0.797806489 1.038521305 0.906497347 0.754543635 0.41252846 0.782829127 1 10.53410504 -4.304499182 1.907878792 0.934476169 0.279525589 0.592502657 0.112301213 0.308432188 1.240049643 0.015097024 0.344928978 4.96E-05 4.304499182 -0.654950581 S(ph)GTNSPPPPFSDWGR ddPTM_HeLa_Curcumin_4h_R1 1 SGTNSPPPPFSDWGR 15 0 D6RAU6;D6REP2;D6RAJ6;Q9UKT5-2;Q9UKT5 D6RAU6 FBXO4 F-box only protein 4 1 0 S(0.826)GT(0.171)NS(0.003)PPPPFSDWGR 183.28 3.76E-05 31173000 4558.7 4076.5 4259 4313.9 4007.6 4653.3 3726.1 4306.4 4935.4 4213.5 TRUE FALSE FALSE 4197.874085 4428.854495 4416.842287 4296.050225 3959.811987 3688.153127 3830.644338 5619.401536 4393.998968 4359.918811 0.962833086 1.015811231 1.013056086 0.985350969 0.908230671 0.845922433 0.878604512 1.288877564 1.007816695 1 12.09008555 -5.95918799 24.91331231 0.98764826 0.961438397 0 0.115267817 795.7002572 485724.1955 0.016136301 0.029249502 1.10E-06 5.95918799 -0.026209863 AASGGS(ph)GSENVGPPAAAVPGPLSR ddPTM_HeLa_Curcumin_4h_R1 2 AASGGSGSENVGPPAAAVPGPLSR 24 0 Q9UL54-2 Q9UL54-2 TAOK2 Serine/threonine-protein kinase TAO2 1 0 AAS(0.115)GGS(0.861)GS(0.024)ENVGPPAAAVPGPLSR;AAS(0.022)GGS(0.956)GS(0.022)ENVGPPAAAVPGPLSR ; 236.19 2.36E-31 16681600 1170.51 672.57 1176.88 1203.04 1058.93 1456.5 1623.08 3193.3 1266.39 917.85 TRUE FALSE FALSE 1077.862898 730.7039539 1220.496208 1198.062139 1046.302951 1154.405482 1668.619257 4166.92247 1127.470185 949.7452192 1.134896893 0.769368394 1.285077496 1.261456352 1.101666984 1.215489648 1.75691251 4.38741084 1.187129098 1 9.891396734 -4.178322192 2.00675829 1.079972243 5.856371033 0.978454028 0.145012436 0.091177087 0.325271905 0.020374901 0.855502479 6.63E-05 4.178322192 4.77639879 up S(ph)GYGPSDGPSYGR ddPTM_HeLa_Curcumin_4h_R1 1 SGYGPSDGPSYGR 13 0 O95429;O95429-2 O95429 BAG4 BAG family molecular chaperone regulator 4 1 0 S(1)GYGPSDGPSYGR 109.95 0.0040585 9653100 1311.9 1436.8 1389.7 1239.6 1480 2699.8 1874.9 1181.6 1717.3 1289.8 TRUE FALSE FALSE 1208.061731 1560.99059 1441.203505 1234.470864 1462.351967 2139.831047 1927.504648 1541.864401 1528.916486 1334.620454 0.905172498 1.169613867 1.079860196 0.924960246 1.095706245 1.60332553 1.444234308 1.155283059 1.145581489 1 10.3822138 -5.443993564 5.504983799 0.981409407 1.402769935 0.572565091 0.136107382 0.094162317 4.906892064 0.018280996 0.041220362 3.60E-06 5.443993564 0.421360527 S(ph)HDSDDS(ph)DYASSK ddPTM_HeLa_Curcumin_4h_R1 1 SHDSDDSDYASSK 13 0 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 2 0 S(0.874)HDS(0.125)DDS(0.982)DY(0.004)AS(0.012)S(0.003)K 113.43 0.0079095 11623000 7594.7 6376.8 6536.5 7046.4 7399 8840.4 6345.4 4396.7 8722.8 7278.6 TRUE FALSE FALSE 6993.571481 6927.982178 6778.74844 7017.243864 7310.771757 7006.801388 6523.434846 5737.23359 7765.930663 7531.530808 0.928572379 0.919863751 0.900049221 0.931715483 0.970688688 0.930328982 0.866149925 0.761761949 1.031122472 1 12.87872741 -3.252137085 0.781259409 0.957079374 1.88E-12 0.723742812 0.037095013 4.086790004 0.557009688 0.006149443 4.948988731 0.000559581 3.252137085 -0.957079374 ASAS(ph)PDRIPSLPQETVDQEPK ddPTM_HeLa_Curcumin_4h_R1 2 ASASPDRIPSLPQETVDQEPK 21 1 A0A494C1R1;A0A2R8Y5U1;Q76L82;Q8IXJ9 A0A494C1R1 ASXH1;ASXL1 Putative Polycomb group protein ASXL1 1 0 AS(0.071)AS(0.929)PDRIPSLPQETVDQEPK;AS(0.167)AS(0.575)PDRIPS(0.111)LPQET(0.147)VDQEPK ; 98.973 8.75E-05 41930000 6090.7 5068.5 5238.4 5651.6 6063.7 6782 5338.1 1933.38 5565.4 5443.4 TRUE FALSE FALSE 5608.614668 5506.598555 5432.539712 5628.215177 5991.394338 5375.336751 5487.872719 2522.858662 4954.889544 5632.557745 0.995749164 0.977637302 0.964488951 0.999229024 1.063707575 0.954333181 0.974312731 0.4479064 0.879687305 1 12.45957448 -4.259486557 5.042095638 0.995642986 0.420873149 0.922533002 0.0459596 0.018021354 1.43948729 0.003699125 0.035940547 5.50E-05 4.259486557 -0.574769837 down S(ph)HNNFVAILDLPEGEHQYK ddPTM_HeLa_Curcumin_4h_R1 1 SHNNFVAILDLPEGEHQYK 19 0 Q9Y478 Q9Y478 PRKAB1 5-AMP-activated protein kinase subunit beta-1 1 0 S(1)HNNFVAILDLPEGEHQYK 61.524 0.0082087 0 674.92 460.3 540.89 572.66 612.59 796.31 639.8 456.57 604.66 751.44 TRUE FALSE FALSE 621.4993698 500.0862809 560.9358592 570.2904847 605.2852643 631.1463297 657.7510661 595.7760912 538.3303108 777.5524841 0.799302147 0.643154374 0.721412214 0.733443075 0.7784494 0.811708975 0.845924976 0.766219777 0.692339516 1 9.602796249 -8.72219371 0.83678176 0.989022115 0.762613947 0 0.106434497 0.244889725 0.340268523 0.030036214 0.012813206 1.90E-09 8.72219371 -0.226408168 S(ph)HSAPSEVGFSDAR ddPTM_HeLa_Curcumin_4h_R1 1 SHSAPSEVGFSDAR 14 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 S(0.436)HS(0.436)APS(0.127)EVGFSDAR 170.26 0.00020291 12656000 963.98 876.4 959.31 788.43 1020.7 1111.8 985.24 389.21 1131.7 869.19 TRUE FALSE FALSE 887.6799658 952.1521108 994.8628725 785.1676856 1008.528819 881.2001474 1012.883183 507.8783373 1007.555341 899.3942878 0.986975321 1.058659282 1.106147644 0.872996078 1.121342255 0.979770674 1.126183696 0.564689307 1.120259885 1 9.812809911 -4.252267349 24.81635957 1.011662843 0.56468905 0.739989991 0.083105389 368.2244716 996265.6205 0.009389931 0.155681155 5.59E-05 4.252267349 -0.446973793 S(ph)HSDTSIASR ddPTM_HeLa_Curcumin_4h_R1 1 SHSDTSIASR 10 0 H7C3H3;E9PEM3;H7C357;H0Y6E6;Q92622-3;Q92622-2;Q92622 H7C3H3 KIAA0226 Run domain Beclin-1 interacting and cysteine-rich containing protein 1 0 S(0.939)HS(0.061)DTSIASR 115.91 0.0056363 0 944.78 817 695.26 798.36 839.59 1255.3 799.45 539.27 1029.6 802.29 TRUE FALSE FALSE 869.9996661 887.6178395 721.0269472 795.0565979 829.5784376 994.9366299 821.8804154 703.6909405 916.6554559 830.1695178 1.047978331 1.069200712 0.868529778 0.957703916 0.999288001 1.198474057 0.990015169 0.847647288 1.104178648 1 9.69726215 S(ph)HSSSEAYEPR ddPTM_HeLa_Curcumin_4h_R1 1 SHSSSEAYEPR 11 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 S(0.893)HS(0.101)S(0.006)SEAYEPR 111.5 0.0061621 2526600 195.88 135.68 50.983 106.22 0 286.74 0 259.13 175.24 160.19 TRUE FALSE FALSE 180.3758913 147.4075746 52.87247483 105.7804898 0 227.2668918 0 338.1375441 156.0166104 165.7565906 1.088197402 0.88930144 0.318976607 0.638167625 0 1.371088118 0 2.039964402 0.941239259 1 7.372922424 -6.99410946 24.73936573 1.038864616 0.680088488 0.041353769 0.58287372 258.3367101 1084965.381 0.083372123 0.109395714 1.01E-07 6.99410946 -0.358776128 S(ph)HTSEGAHLDITPNSGAAGNSAGPK ddPTM_HeLa_Curcumin_4h_R1 5 SHTSEGAHLDITPNSGAAGNSAGPK 25 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 0 S(0.829)HT(0.118)S(0.05)EGAHLDIT(0.003)PNSGAAGNSAGPK;S(0.444)HT(0.444)S(0.112)EGAHLDITPNSGAAGNSAGPK;S(0.441)HT(0.441)S(0.118)EGAHLDITPNSGAAGNSAGPK;S(0.869)HT(0.095)S(0.035)EGAHLDITPNSGAAGNSAGPK;S(0.463)HT(0.432)S(0.105)EGAHLDITPNSGAAGNSAGPK ;;;; 128.18 1.78E-08 73194700 14664.8 12336.48 11717.2 12007.49 17797.2 35336.4 14569.9 7480.78 19194.5 12098.4 TRUE FALSE FALSE 13504.06561 13402.79036 12151.44974 11957.80619 17584.98001 28007.23232 14978.69218 9761.635385 17088.91137 12518.8185 1.078701285 1.070611445 0.970654678 0.955186481 1.404683678 2.23721051 1.196494077 0.779756922 1.365057843 1 13.61181079 -5.721588881 7.319382009 1.030180429 1.451603726 0.16190789 0.355176526 0.224519811 32.57500277 0.048780208 0.09714686 1.90E-06 5.721588881 0.421423297 QDS(ph)WEVVEGLR ddPTM_HeLa_Curcumin_4h_R1 2 QDSWEVVEGLR 11 0 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3;Q9H4L5-6;Q9H4L5-2;Q9H4L5-8;Q9H4L5-4;C9J8P4;C9JEF2;C9JZ19 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 0 QDS(1)WEVVEGLR;QDS(1)WEVVEGLR ; 138.01 0.0016453 9868100 2723.85 2692.6 2300.74 2536.95 2778.8 3598.7 3346.2 5847.5 2532.03 2519.1 TRUE FALSE FALSE 2508.254398 2925.336346 2386.007448 2526.452773 2745.664625 2852.289054 3440.085366 7630.375831 2254.272644 2606.638537 0.962256317 1.122263906 0.915358004 0.969237866 1.053335392 1.094240346 1.319740085 2.927285744 0.86481981 1 11.34797482 -4.177518552 2.156806662 0.995150894 3.738917321 0.983388138 0.074871145 0.063389293 0.271008722 0.008916576 0.360836698 6.64E-05 4.177518552 2.743766427 up S(ph)IDDLEDELYAQK ddPTM_HeLa_Curcumin_4h_R1 1 SIDDLEDELYAQK 13 0 P09493-4;P09493-10;A0A0S2Z4G6;P09493;H0YKJ4;H0YK48;P09493-6;A0A494C0I0 P09493-4 TPM1 Tropomyosin alpha-1 chain 1 0 S(1)IDDLEDELYAQK 209.19 6.28E-40 0 1020.6 960.02 1314.4 1011.7 993.55 1496 1327.5 864.9 1303.6 933.7 TRUE FALSE FALSE 939.8184331 1042.999851 1363.11282 1007.513853 981.7025652 1185.712737 1364.746077 1128.604028 1160.598341 966.1460055 0.972749903 1.079546823 1.41087663 1.042817388 1.016101665 1.227260404 1.412567117 1.168150592 1.201265994 1 9.916097418 -6.454066116 0.483547845 0.973972934 1.273579032 0.042706639 0.149708438 0.857538013 0.405422505 0.043436974 0.105818172 3.52E-07 6.454066116 0.299606098 S(ph)IDDLEEK ddPTM_HeLa_Curcumin_4h_R1 4 SIDDLEEK 8 0 P09493-3;P09493-9;H7BYY1;Q6ZN40;P09493-2;P09493-8;P09493-7 P09493-3 TPM1 Tropomyosin alpha-1 chain 1 0 S(1)IDDLEEK;S(1)IDDLEEK;S(1)IDDLEEK;S(1)IDDLEEK ;;; 164.66 0.0005856 562025000 18138.1 15393 16864.3 16858.2 15793.9 21093.9 18206.7 15153.3 17265.5 13272.6 TRUE FALSE FALSE 16702.45025 16723.50233 17489.30579 16788.44524 15605.56806 16718.78736 18717.531 19773.47141 15371.51785 13733.82186 1.216154572 1.217687436 1.273447841 1.22241612 1.136287351 1.217344125 1.362878534 1.439764664 1.119245466 1 13.74544554 -13.52287875 0.066308507 0.032806566 1.639503503 0.61124131 0.073021222 106.2682547 0.549613809 16.32202075 2.593469529 3.00E-14 13.52287875 1.606696937 S(ph)IDQDYER ddPTM_HeLa_Curcumin_4h_R1 2 SIDQDYER 8 0 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;A0A3B3IRI3;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISZ5;Q9UDY2-5;A0A3B3IRV6;A0A3B3ISF1 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 S(1)IDQDYER;S(1)IDQDYER ; 132.25 0.0048232 343170000 5013.3 4201.1 4239.3 4165.8 4428.5 4486.5 4334.7 4500.9 4557.2 3969.8 TRUE FALSE FALSE 4616.492015 4564.224364 4396.412187 4148.563023 4375.69303 3555.949327 4456.320016 5873.20369 4057.286562 4107.750255 1.123849243 1.111125088 1.070272513 1.009935553 1.065228594 0.865668336 1.08485661 1.429785972 0.987715005 1 12.00413276 -4.271203637 4.890569669 1.048712795 1.447289933 0.729858548 0.071845333 0.069557354 4.878313678 0.01052017 0.092289714 5.36E-05 4.271203637 0.398577138 S(ph)IDS(ph)TKSRS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 SIDSTKSRSR 10 2 Q8N2Y8 Q8N2Y8 RUSC2 Iporin 3 0 S(0.984)IDS(0.832)T(0.184)KS(0.001)RS(1)R;S(0.973)IDS(0.838)T(0.187)KS(0.002)RS(0.999)R ; 97.957 0.010282 76512000 0 0 64.476 112.789 117.46 0 0 0 0 0 TRUE FALSE FALSE 0 0 66.86553728 112.322309 116.0593662 0 0 0 0 0 0 S(ph)IEDDEEGHLICQSGDVLR ddPTM_HeLa_Curcumin_4h_R1 2 SIEDDEEGHLICQSGDVLR 19 0 Q9HAZ1;B7ZL31;A0A087WX74 Q9HAZ1 CLK4 Dual specificity protein kinase CLK4 1 0 S(1)IEDDEEGHLICQSGDVLR;S(0.954)IEDDEEGHLICQS(0.046)GDVLR ; 149.8 3.35E-05 25240000 3522.9 2810.1 2708.7 3104 3845 4046.5 3314.9 2653.2 4132.4 3232 TRUE FALSE FALSE 3244.058748 3052.992522 2809.086805 3091.15647 3799.150886 3207.210287 3407.907172 3462.148466 3679.086059 3344.311759 0.970022827 0.912891124 0.839959611 0.924302724 1.136003806 0.959004578 1.019015994 1.035234965 1.100102599 1 11.70749363 S(ph)IEDLHR ddPTM_HeLa_Curcumin_4h_R1 2 SIEDLHR 7 0 Q96PY5;Q96PY5-3 Q96PY5 FMNL2 Formin-like protein 2 1 0 S(1)IEDLHR;S(1)IEDLHR ; 140.14 0.0016341 234760000 19236.8 13672.5 15551.2 16347.5 18072.2 20401.4 14917.9 14447.6 19509.8 15430.1 TRUE FALSE FALSE 17714.18698 14854.28998 16127.54115 16279.85838 17856.70082 16169.91967 15336.45612 18852.60673 17369.62375 15966.29483 1.109473874 0.93035298 1.01009917 1.019639093 1.118399792 1.012753419 0.960551981 1.180775311 1.087893211 1 13.96274194 -3.106733712 10.1355314 1.042501036 1.045538757 0 0.074150421 0 0 0.009550608 0 0.000782107 3.106733712 0.003037721 REGT(ph)PPPPPPSR ddPTM_HeLa_Curcumin_4h_R1 2 REGTPPPPPPSR 12 1 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 REGT(1)PPPPPPSR;REGT(1)PPPPPPSR ; 85.976 0.0099322 104746000 5904.4 5037.3 4491.7 4967.9 4469.3 5721 4845.6 1132.67 6321.7 4842.2 TRUE FALSE FALSE 5437.06051 5472.701766 4658.166353 4947.344146 4416.006516 4534.400111 4981.554495 1478.015869 5628.225326 5010.46609 1.085140666 1.092254028 0.929687233 0.987401982 0.881356432 0.90498569 0.994229759 0.294985704 1.123293767 1 12.2907291 -4.259466182 5.519802652 1.012507146 0.268340063 0.880800075 0.077686519 0.037234904 4.365105536 0.011279795 0.103834915 5.50E-05 4.259466182 -0.744167084 down S(ph)IEVENDFLPVEK ddPTM_HeLa_Curcumin_4h_R1 2 SIEVENDFLPVEK 13 0 Q5JPT2;Q96B97-2;Q96B97;Q5JPT1;Q5VSN0 Q5JPT2 SH3KBP1 SH3 domain-containing kinase-binding protein 1 1 0 S(1)IEVENDFLPVEK;S(1)IEVENDFLPVEK ; 200 5.67E-07 168234000 15396.8 13265.2 12723.7 13617.8 14245.8 16652.9 12997 5901.2 15020.9 12932.9 TRUE FALSE FALSE 14178.12703 14411.78478 13195.25151 13561.45315 14075.92814 13198.90082 13361.66084 7700.448714 13373.14485 13382.31731 1.059467258 1.076927444 0.98602142 1.01338601 1.051830398 0.986294116 0.998456435 0.575419678 0.999314583 1 13.70804034 -4.25368344 4.033633077 1.026770155 0.53225515 0.950652637 0.030343366 0.039241714 1.324612855 0.004568087 0.05687941 5.58E-05 4.25368344 -0.494515004 AGGLDWPEATEVSPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 AGGLDWPEATEVSPSR 16 0 Q9Y446;Q9Y446-2;E9PKC4;E9PK71;E9PJR7;E9PRW6 Q9Y446 PKP3 Plakophilin-3 1 0 AGGLDWPEATEVS(0.456)PS(0.544)R 216.77 3.28E-15 50889000 5105.6 4400.5 4657.5 4319.2 4652 5933.9 4206.2 1477.7 5102.9 4365.4 TRUE FALSE FALSE 4701.486373 4780.859612 4830.111047 4301.328295 4596.527938 4703.142251 4324.214652 1928.243928 4543.124637 4517.097325 1.040820251 1.058391987 1.069295324 0.952232814 1.017584437 1.041186831 0.95729942 0.426876773 1.005761955 1 12.14118028 -4.259366541 3.59750405 1.021985572 0.357338227 0.969374648 0.031595047 0.033881775 0.7807347 0.004535705 0.060589343 5.50E-05 4.259366541 -0.664647345 down DLTSLETTS(ph)EMEAGSPENKK ddPTM_HeLa_Curcumin_4h_R1 1 DLTSLETTSEMEAGSPENKK 20 1 Q5VYS8-4;Q5VYS8;Q5VYS8-5;Q5VYS8-3;Q5VYS8-2;Q5VYS8-6 Q5VYS8-4 ZCCHC6 Terminal uridylyltransferase 7 1 0 DLTSLET(0.078)T(0.389)S(0.52)EMEAGS(0.012)PENKK 113.28 0.00011616 20649000 2837.4 2417.3 3007.6 3055 2778.2 3416 2483.2 780.64 3245.9 2517.5 TRUE FALSE FALSE 2612.816796 2626.240641 3119.064302 3042.359219 2745.07178 2707.483094 2552.871909 1018.653542 2889.832891 2604.982938 1.003007259 1.0081604 1.197345386 1.167899864 1.053777259 1.039347726 0.979995635 0.391040389 1.109348107 1 11.34705821 -4.259102096 3.992182532 1.03314731 0.331556602 0.881108156 0.073516666 0.06543531 2.149136835 0.01113635 0.132851422 5.51E-05 4.259102096 -0.701590707 down S(ph)IHEVDISNLEAALR ddPTM_HeLa_Curcumin_4h_R1 2 SIHEVDISNLEAALR 15 0 A0A1B0GUN5;Q5VTI5;Q9Y2H5 A0A1B0GUN5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 0 S(1)IHEVDISNLEAALR;S(1)IHEVDISNLEAALR ; 141.82 0.00052265 13442100 1696.36 1411.5 1352.84 1848.77 1449.45 1698.21 1601.04 1116.99 1579.04 1354.2 TRUE FALSE FALSE 1562.091316 1533.50377 1402.97744 1841.12028 1432.166255 1345.982103 1645.960873 1457.555109 1405.823263 1401.258349 1.114777526 1.094376188 1.00122682 1.313904949 1.02205725 0.960552423 1.174630556 1.04017586 1.003257724 1 10.45250725 -9.354145483 0.980704515 0.997767702 1.092689377 0.121642721 0.094757692 1.007699478 1.668957247 0.069468728 0.016489909 4.42E-10 9.354145483 0.094921675 LLSPQMS(ph)GEEEDSDLAAK ddPTM_HeLa_Curcumin_4h_R1 3 LLSPQMSGEEEDSDLAAK 18 0 P42858;A0A3B3IU44 P42858 HTT Huntingtin 1 0 LLS(0.029)PQMS(0.97)GEEEDSDLAAK;LLS(0.468)PQMS(0.532)GEEEDSDLAAK;LLS(0.32)PQMS(0.678)GEEEDS(0.001)DLAAK ;; 116.13 0.00053052 50231000 2846.84 2470.7 2775.6 2752.79 2719.39 4432.67 6489.3 15494.1 1375.36 2697.51 TRUE FALSE FALSE 2621.50961 2684.256299 2878.466178 2741.399684 2686.96305 3513.284276 6671.372293 20218.17976 1224.486449 2791.248272 0.939188977 0.961668772 1.031246918 0.982141113 0.9626385 1.258678531 2.390103511 7.243418641 0.438687759 1 11.44669474 -4.176136351 1.911404198 0.978900573 10.16046618 0.99022756 0.187844754 0.031995318 0.100558402 0.012744914 0.557169142 6.67E-05 4.176136351 9.181565605 up S(ph)ILVSPTGPSR ddPTM_HeLa_Curcumin_4h_R1 2 SILVSPTGPSR 11 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 0 S(0.999)ILVS(0.001)PTGPSR;S(0.997)ILVS(0.003)PTGPSR ; 139.31 0.0014516 87356000 4455.6 3960.8 4422.6 4372.2 4138.3 6629.4 5655.8 4182.5 4955.7 3798.5 TRUE FALSE FALSE 4102.934558 4303.153903 4586.505447 4354.108995 4088.953475 5254.387711 5814.486526 5457.724996 4412.072109 3930.497592 1.043871536 1.094811484 1.166901986 1.107775515 1.040314459 1.336825068 1.479325808 1.388558285 1.122522532 1 11.94049625 -5.169854667 3.208662809 1.045018933 1.431798019 0.857817428 0.058905429 0.061878182 1.217834389 0.009127086 0.02585797 6.76E-06 5.169854667 0.386779085 S(ph)IMAEPDY(ph)IEDDNPELIR ddPTM_HeLa_Curcumin_4h_R1 1 SIMAEPDYIEDDNPELIR 18 0 Q9H098-2 Q9H098-2 2 0 S(1)IMAEPDY(1)IEDDNPELIR 74.392 0.0069772 13439000 1255.7 925.43 949.62 1243.3 857.22 980.82 857.23 399.59 1036.3 1011 TRUE FALSE FALSE 1156.31002 1005.420046 984.8137526 1238.155554 846.9982114 777.3868759 881.2815667 521.4231515 922.6204827 1046.132175 1.10531924 0.961083188 0.941385588 1.183555562 0.809647415 0.74310579 0.842418949 0.498429514 0.881934907 1 10.03084943 -3.911167129 0.542071762 1.048387788 1.30E-05 0.620942326 0.112783843 2.04039298 0.31059028 0.019327001 1.466025636 0.000122697 3.911167129 -1.048374754 S(ph)IPAGAEPGEK ddPTM_HeLa_Curcumin_4h_R1 1 SIPAGAEPGEK 11 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 0 S(1)IPAGAEPGEK 99.732 0.011254 17848000 2457.1 2483 2436.5 2877.6 2438.9 3288.1 2750.3 2455.4 2683.9 2774.1 TRUE FALSE FALSE 2262.617942 2697.619456 2526.798833 2865.693254 2409.81771 2606.110995 2827.466016 3204.040157 2389.482885 2870.499769 0.788231362 0.939773445 0.880264427 0.998325548 0.83951155 0.907894515 0.985008272 1.116195929 0.832427479 1 11.48708622 -4.374104737 2.127788903 0.90241983 1.146838848 0.516027365 0.065302449 0.417805231 2.500098177 0.01170283 0.176747651 4.23E-05 4.374104737 0.244419018 S(ph)IQDLTVTGTEPGQVSS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SIQDLTVTGTEPGQVSSR 18 0 Q9UG54;O43318-4;O43318-3;O43318-2;O43318 Q9UG54 DKFZp586F0420;MAP3K7 Mitogen-activated protein kinase kinase kinase 7 2 0 S(1)IQDLTVTGTEPGQVS(0.408)S(0.592)R 205.8 7.97E-12 8710100 1569.7 1240.4 1373.6 1515.6 1215.7 1313.3 1035.1 1198 1271.1 1075.2 TRUE FALSE FALSE 1445.456589 1347.614649 1424.506824 1509.328849 1201.203571 1040.906776 1064.14212 1563.264685 1131.66351 1112.56312 1.299213108 1.211270286 1.280382927 1.356623118 1.07967229 0.935593457 0.956477975 1.405102018 1.017167916 1 10.11967147 -4.226728088 23.01681534 1.145157311 1.405103582 0.239182796 0.145727486 7926.670196 5255850.888 0.023051257 4.972919988 5.93E-05 4.226728088 0.259946271 S(ph)IQDLTVTGTEPGQVSSR ddPTM_HeLa_Curcumin_4h_R1 2 SIQDLTVTGTEPGQVSSR 18 0 Q9UG54;O43318-4;O43318-3;O43318-2;O43318 Q9UG54 DKFZp586F0420;MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1 0 S(1)IQDLTVTGTEPGQVSSR;S(1)IQDLTVTGTEPGQVSSR ; 294.39 1.24E-81 158354000 3690.9 2914.6 3434.8 3231.7 3460.8 4512.7 3278.7 4648.4 3106.7 3525.9 TRUE FALSE FALSE 3398.76137 3166.525037 3562.09671 3218.328082 3419.53222 3576.715151 3370.691498 6065.675761 2765.902783 3648.424763 0.931569538 0.867915674 0.976338267 0.882114417 0.937262639 0.980345049 0.923875842 1.662546484 0.758108763 1 11.83305799 -4.260066839 24.99647797 0.951929718 1.662546715 0.899493327 0.07391194 16.70824817 304255.0121 0.006407148 0.053605682 5.49E-05 4.260066839 0.710616998 S(ph)IQFVDWCPTGFK ddPTM_HeLa_Curcumin_4h_R1 2 SIQFVDWCPTGFK 13 0 P68363;P68363-2;P68366-2;P68366 P68363;P68366-2 TUBA1B;TUBA4A Tubulin alpha-1B chain;Tubulin alpha-4A chain 1 0 S(1)IQFVDWCPTGFK;S(1)IQFVDWCPTGFK ; 121.99 0.0023236 74023000 6561 5239.6 6272.4 5467.4 5709.6 8720.2 6666.3 5983.3 5946 5577.8 TRUE FALSE FALSE 6041.689927 5692.487677 6504.860662 5444.777347 5641.516749 6911.532223 6853.338437 7807.580626 5293.738676 5771.628135 1.046791267 0.986288019 1.127040847 0.943369396 0.977456728 1.197501305 1.187418572 1.352751848 0.917200234 1 12.49476263 -4.792000171 1.464320886 1.019669382 1.334932066 0.739011189 0.067293775 0.181185288 0.628552135 0.008272754 0.06235262 1.61E-05 4.792000171 0.315262684 S(ph)IS(ph)REPSPALGPNLDGSGLLPR ddPTM_HeLa_Curcumin_4h_R1 1 SISREPSPALGPNLDGSGLLPR 22 1 Q9BRZ2 Q9BRZ2 TRIM56 E3 ubiquitin-protein ligase TRIM56 2 0 S(0.667)IS(0.667)REPS(0.667)PALGPNLDGSGLLPR 56.766 0.0097383 22146000 1759.5 1360.1 1574.3 1206.2 1484.9 1889.7 1499.5 932.14 1556.2 1195.3 TRUE FALSE FALSE 1620.233718 1477.660984 1632.644943 1201.209064 1467.193537 1497.754919 1541.571934 1216.345195 1385.488753 1236.836586 1.309982043 1.194709956 1.320016695 0.971194641 1.186246877 1.210956189 1.24638287 0.983432418 1.120187395 1 10.27243919 -9.576965033 1.380686189 1.000726287 1.197271874 0.09165673 0.118171945 0.432528218 1.487005612 0.077891274 0.018497922 2.65E-10 9.576965033 0.196545587 S(ph)ISESFLTVK ddPTM_HeLa_Curcumin_4h_R1 2 SISESFLTVK 10 0 J3KSQ9;K7EP00;F5H527;Q76I76-3;Q76I76-4;Q76I76 J3KSQ9 SSH2 Protein phosphatase Slingshot homolog 2 1 0 S(0.973)IS(0.027)ESFLTVK;S(0.957)IS(0.042)ES(0.001)FLT(0.001)VK ; 178.71 0.00033403 42430000 2853.5 1896.68 1961.06 2210.93 2757.6 2915.8 2001.36 1394.66 2697.3 2182.39 TRUE FALSE FALSE 2627.642464 2060.620568 2033.738609 2201.781757 2724.717421 2311.030212 2057.512775 1819.885414 2401.412938 2258.22789 1.163586047 0.912494517 0.900590511 0.975004235 1.206573275 1.023382194 0.911118308 0.805890947 1.063405934 1 11.14097537 -4.60678966 2.607762126 1.054013116 0.814797108 0.355027147 0.094205758 0.250895838 3.135620202 0.015328124 0.09362381 2.47E-05 4.60678966 -0.239216008 S(ph)ISESSR ddPTM_HeLa_Curcumin_4h_R1 2 SISESSR 7 0 Q9H307 Q9H307 PNN Pinin 1 0 S(0.981)IS(0.013)ES(0.007)SR;S(0.988)IS(0.012)ES(0.001)SR ; 123.21 0.010373 149985000 6277.3 8079.8 5557.1 4524.2 4441.6 4846.2 2473.6 1858 4150.1 4762 TRUE FALSE FALSE 5780.445081 8778.181909 5763.051015 4505.480059 4388.636821 3841.043492 2543.002559 2424.495647 3694.844413 4927.479146 1.173103916 1.781475203 1.169573903 0.914358017 0.890645438 0.779514916 0.51608591 0.492035699 0.749844759 1 12.26663405 -5.272117445 1.136266575 1.144668256 0.476637732 0.505394374 0.250002778 0.350622193 0.789597024 0.038031233 0.17918989 5.34E-06 5.272117445 -0.668030524 S(ph)ISGTSTSEKPNSMDTANTSPFK ddPTM_HeLa_Curcumin_4h_R1 2 SISGTSTSEKPNSMDTANTSPFK 23 1 Q9UJF2-2;Q9UJF2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 0 S(0.769)IS(0.144)GT(0.022)S(0.025)T(0.028)S(0.013)EKPNSMDTANTSPFK;S(0.218)IS(0.025)GT(0.181)S(0.181)T(0.181)S(0.181)EKPNS(0.027)MDT(0.005)ANTSPFK ; 92.819 6.68E-05 77356000 3968 3240.75 3695.7 3908.9 4340.8 4978.9 4439.7 3876.7 3456.8 3009 TRUE FALSE FALSE 3653.928613 3520.865989 3832.665893 3892.726008 4289.038795 3946.220016 4564.266033 5058.687984 3077.597688 3113.562526 1.173552348 1.130815893 1.230958383 1.25024822 1.377534178 1.267429185 1.465930424 1.624726641 0.988448975 1 11.60435054 -1 0.185863947 0.990487009 3.61313804 0.916109538 0.054566396 10.94495168 0.120944598 0.064580212 8.234810771 0.1 1 2.622651031 S(ph)ISNPPGSNLR ddPTM_HeLa_Curcumin_4h_R1 2 SISNPPGSNLR 11 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 0 S(0.931)IS(0.069)NPPGSNLR;S(0.997)IS(0.003)NPPGS(0.001)NLR ; 128.57 0.001632 18648000 4262.3 2398.4 3648 4337.1 3785 4330.9 3027.7 2324.71 2913.2 2575.3 TRUE FALSE FALSE 3924.934457 2605.707009 3783.198089 4319.154229 3739.866347 3432.622521 3112.649113 3033.503377 2593.629248 2664.791483 1.472886146 0.977827731 1.419697606 1.620822588 1.403436768 1.288139257 1.168064793 1.138364257 0.973295383 1 11.37980693 -9.504841747 1.187579925 0.995597932 1.329468465 0.346576149 0.175833654 0.491111819 1.212772985 0.137235989 0.031419864 3.13E-10 9.504841747 0.333870533 S(ph)ISPEWK ddPTM_HeLa_Curcumin_4h_R1 1 SISPEWK 7 0 F5H6E2;O00159-2;O00159-3;O00159 F5H6E2 MYO1C Unconventional myosin-Ic 1 0 S(0.999)IS(0.001)PEWK 112.41 0.015343 26005000 5099.9 4057.3 4693.9 4498.5 4427.3 5112.7 3770 4335.4 4998.3 3774 TRUE FALSE FALSE 4696.237534 4407.994933 4867.860063 4479.886399 4374.507339 4052.268388 3875.776054 5657.243502 4449.998995 3905.146219 1.202576618 1.128765656 1.246524404 1.147175073 1.120190409 1.037673921 0.992479112 1.448663682 1.139521735 1 11.93116085 -9.378965473 1.047573031 0.997958001 1.158368737 0.039083352 0.124973343 0.677382781 1.302813099 0.081800478 0.020005095 4.18E-10 9.378965473 0.160410736 S(ph)ISREPS(ph)PALGPNLDGSGLLPR ddPTM_HeLa_Curcumin_4h_R1 1 SISREPSPALGPNLDGSGLLPR 22 1 Q9BRZ2 Q9BRZ2 TRIM56 E3 ubiquitin-protein ligase TRIM56 2 0 S(0.725)IS(0.283)REPS(0.988)PALGPNLDGS(0.004)GLLPR 56.573 0.0098914 7682500 1029.7 984.64 1097.9 853.38 1020.9 1298.2 1090.8 581.83 960.69 691.01 TRUE FALSE FALSE 948.1981585 1069.747894 1138.58914 849.8489397 1008.726434 1028.938686 1121.404912 759.2272886 855.3047105 715.0225461 1.326109454 1.496103724 1.592382151 1.188562437 1.410761716 1.439029709 1.568349024 1.061822865 1.196192645 1 9.481844923 -8.688465882 0.74749 1.010205051 1.400158003 0.302909916 0.164958431 0.400398171 0.442904943 0.081789218 0.032948379 2.05E-09 8.688465882 0.389952952 S(ph)ISTSGPLDKEDTGR ddPTM_HeLa_Curcumin_4h_R1 1 SISTSGPLDKEDTGR 15 1 A0A0U1RR27;Q7Z401;Q7Z401-2 A0A0U1RR27 DENND4A C-myc promoter-binding protein 1 0 S(0.978)IS(0.007)T(0.007)S(0.007)GPLDKEDTGR 153.74 0.0038201 16686000 1975.5 1876.3 2103.9 1950 1742.2 2299.3 1699.2 662.59 2166.9 2356 TRUE FALSE FALSE 1819.13709 2038.479011 2181.872385 1941.931417 1721.425403 1822.399262 1746.874979 864.6106408 1929.196491 2437.870825 0.746199131 0.836171872 0.894990974 0.796568627 0.706118382 0.747537254 0.716557646 0.354658103 0.791344837 1 11.25140597 -3.294285243 0.224666745 0.94503816 3.06E-66 0.593563238 0.101479127 10.17438045 0.298541624 0.088969995 2.874136464 0.000507826 3.294285243 -0.94503816 S(ph)ITST(ph)PLSGK ddPTM_HeLa_Curcumin_4h_R1 1 SITSTPLSGK 10 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3 RAI14 Ankycorbin 2 0 S(1)ITS(0.001)T(0.977)PLS(0.022)GK 152.38 0.0029644 27153000 5437.3 4831.2 4785.2 4519.9 5872.9 9013.7 11636 5042.2 6023.1 5093.5 TRUE FALSE FALSE 5006.931968 5248.787401 4962.543721 4501.197851 5802.869503 7144.157015 11962.47484 6579.543569 5362.380999 5270.498746 0.949992061 0.99588059 0.941570041 0.854036414 1.10100956 1.355499234 2.269704523 1.248372096 1.017433313 1 12.36372377 -5.092512712 3.191058241 0.97187557 1.769114716 0.620742648 0.241473232 0.097252209 1.881761844 0.029382597 0.087560022 8.08E-06 5.092512712 0.797239146 S(ph)ITSTPLSGK ddPTM_HeLa_Curcumin_4h_R1 1 SITSTPLSGK 10 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3 RAI14 Ankycorbin 1 0 S(0.955)IT(0.023)S(0.023)TPLSGK 99.5 0.012909 16455000 2125.7 1729.1 1639.1 1843 2066.4 2790.2 2656.2 2059.7 2211.4 2506.4 TRUE FALSE FALSE 1957.448602 1878.555699 1699.846488 1835.374154 2041.75953 2211.481068 2730.725823 2687.693048 1968.814953 2593.497213 0.754752537 0.724333032 0.655426379 0.707683102 0.787261123 0.852702311 1.052912573 1.036320006 0.759135172 1 11.3406831 -4.785375942 5.73300379 0.832411506 1.046234642 0.473344095 0.100214742 0.155430121 15.21623628 0.019191192 0.06317503 1.64E-05 4.785375942 0.213823136 S(ph)IVVIHPDTGR ddPTM_HeLa_Curcumin_4h_R1 3 SIVVIHPDTGR 11 0 K7EQ71;K7EKI8;O60437 K7EQ71 PPL Periplakin 1 0 S(1)IVVIHPDTGR;S(1)IVVIHPDTGR;S(1)IVVIHPDTGR ;; 96.707 0.0061894 30455300 10084.3 9163.6 9288.6 10535.6 10794.8 14450.9 13863.6 8572.6 10334.7 9005.6 TRUE FALSE FALSE 9286.117014 9955.660752 9632.843687 10492.00648 10666.07906 11453.62044 14252.5753 11186.34628 9201.009266 9318.54393 0.996520174 1.068370856 1.033728419 1.125927673 1.144607907 1.229121259 1.52948523 1.200439292 0.987387014 1 13.18588883 -5.501104772 0.965533762 1.003360816 1.375568698 0.704071311 0.084748241 0.21567022 0.359083631 0.012632624 0.05293071 3.15E-06 5.501104772 0.372207881 S(ph)KFDSDEEEEDTENVEAASSGK ddPTM_HeLa_Curcumin_4h_R1 3 SKFDSDEEEEDTENVEAASSGK 22 1 Q8TF01;Q8TF01-2 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 0 S(0.5)KFDS(0.5)DEEEEDTENVEAASSGK;S(0.498)KFDS(0.498)DEEEEDT(0.004)ENVEAASSGK;S(0.515)KFDS(0.057)DEEEEDT(0.428)ENVEAASSGK ;; 99.873 5.15E-05 194709000 13736.8 10110.3 10409.6 11058 11831.7 13029.1 12238.6 11043.7 13736.6 9110.2 TRUE FALSE FALSE 12649.51778 10984.18928 10795.38893 11012.24493 11690.61471 10326.71779 12581.98218 14410.87329 12229.72935 9426.778772 1.341870653 1.165211314 1.145183227 1.168187479 1.240149471 1.095466229 1.334706423 1.52871661 1.29733917 1 13.20254916 -9.458015572 1.11429286 0.995696769 1.250123908 0 0.149776791 0.459183807 0.991763109 0.093337243 0.02156096 3.48E-10 9.458015572 0.254427139 ETDSPST(ph)PGKDQR ddPTM_HeLa_Curcumin_4h_R1 1 ETDSPSTPGKDQR 13 1 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 0 ETDS(0.001)PS(0.228)T(0.77)PGKDQR 154.13 3.67E-05 0 1964.8 1762.2 1942.6 1863.4 1984.8 1722.3 1366.3 366.16 2119.8 1618.1 TRUE FALSE FALSE 1809.284007 1914.516716 2014.594465 1855.689745 1961.132556 1365.075566 1404.634701 477.8004984 1887.263243 1674.328855 1.080602536 1.143453217 1.203225077 1.10831856 1.171294726 0.815297163 0.838924024 0.285368371 1.127175966 1 10.7093672 -4.259059733 1.31078989 1.069168014 1.03E-12 0.876404059 0.092432134 0.373327885 0.540140167 0.014273342 0.533126937 5.51E-05 4.259059733 -1.069168014 down S(ph)KS(ph)DPIMLLK ddPTM_HeLa_Curcumin_4h_R1 1 SKSDPIMLLK 10 1 P08559-3;P08559;P08559-2;P08559-4;Q5JPU3 P08559-3 PDHA1 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial" 2 0 S(1)KS(1)DPIMLLK 47.187 0.018656 12480000 2412 2312.7 2017.3 2765 2301 1222.4 1322.1 1165 2580 2025.9 TRUE FALSE FALSE 2221.087655 2512.599483 2092.062913 2753.559163 2273.562078 968.8604607 1359.194568 1520.203137 2296.980455 2096.299874 1.059527638 1.198587814 0.997978838 1.313533048 1.084559564 0.462176463 0.648377927 0.725184004 1.095730856 1 11.03362939 -5.27219911 24.74875821 1.064722606 0.615559312 0.798881824 0.112460326 209.3267138 481478.4163 0.016549314 0.037361343 5.34E-06 5.27219911 -0.449163293 S(ph)KS(ph)LAFHTMLT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SKSLAFHTMLTK 12 1 Q14D04-2;Q14D04 Q14D04-2 VEPH1 Ventricular zone-expressed PH domain-containing protein homolog 1 3 0 S(1)KS(0.998)LAFHT(0.002)MLT(1)K 80.102 0.0071269 12647000 2429.7 2882.2 2537 2609.1 2295.5 2157.6 1781.8 2564.2 3506.7 3201.9 TRUE FALSE FALSE 2237.386681 3131.324525 2631.023452 2598.304236 2268.127662 1710.089439 1831.792513 3346.012776 3122.023783 3313.165787 0.675301758 0.945115556 0.79411162 0.784236106 0.684580189 0.516149673 0.552882841 1.00991408 0.942308349 1 11.69399468 -5.968403633 2.265482276 0.848368285 0.668290302 0.230635994 0.150718177 0.395033161 4.078349414 0.026113451 0.050779549 1.08E-06 5.968403633 -0.180077984 S(ph)KS(ph)RS(ph)RS(ph)ES(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SKSRSRSESR 10 3 P62995 P62995;REV__Q5VT06 TRA2B Transformer-2 protein homolog beta 5 0 S(1)KS(1)RS(1)RS(1)ES(1)R 47.915 0.0094328 0 1155.3 1321.2 1441.7 1277.9 1160.6 1677.5 1479 1346.3 1671.4 2075.3 TRUE FALSE FALSE 1063.856786 1435.398641 1495.13067 1272.612388 1146.760603 1329.567591 1520.496759 1756.780672 1488.051602 2147.416521 0.495412406 0.668430473 0.696246236 0.592624848 0.534018711 0.61914751 0.708058611 0.818090322 0.692949685 1 11.06838633 -9.437951669 1.128763826 1.003230924 0.627210856 0.14883953 0.126995189 0.234409217 0.526845093 0.070072898 0.016915649 3.65E-10 9.437951669 -0.376020068 S(ph)KS(ph)RS(ph)S(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 SKSRSSSK 8 2 P30414;A0A087WYW3;Q8WXA9;Q8WXA9-2 P30414 NKTR;SREK1 NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase;Splicing regulatory glutamine/lysine-rich protein 1 4 0 S(1)KS(1)RS(1)S(0.987)S(0.013)K 52.683 0.020047 18695000 1066.5 998.87 1059.2 971.57 814.15 1413.6 1172.2 1475.8 1427.4 935.01 TRUE FALSE FALSE 982.0853996 1085.207872 1098.454884 967.5499008 804.441793 1120.403425 1205.088777 1925.764626 1270.817791 967.5015279 1.015073745 1.121660112 1.135352092 1.000049998 0.831463072 1.158037887 1.245567829 1.990451251 1.313504687 1 9.918120129 -4.103967754 1.614561503 1.016731711 2.655214139 0.820155565 0.127102678 0.294124063 0.530590116 0.012306128 0.846068535 7.87E-05 4.103967754 1.638482428 S(ph)KSDATASISLSSNLK ddPTM_HeLa_Curcumin_4h_R1 1 SKSDATASISLSSNLK 16 1 Q9UBF8-2;A0A0B4J1S8;Q9UBF8 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 0 S(0.658)KS(0.322)DAT(0.015)AS(0.004)ISLSSNLK 130.02 0.0044597 28484000 1852.1 1432.4 1856.2 1694.7 1627.4 1809.4 1655.2 1458.2 1640.8 1813.1 TRUE FALSE FALSE 1705.504331 1556.210273 1924.992405 1687.68778 1607.994318 1434.110044 1701.640457 1902.798467 1460.808345 1876.10509 0.909066523 0.829489927 1.026057877 0.89956996 0.857091816 0.764408162 0.907007004 1.014228082 0.778638869 1 10.87352493 -9.057222592 0.501513503 1.017430734 0.892591731 0 0.101378246 1.718213372 0.663649341 0.103923182 0.020839257 8.77E-10 9.057222592 -0.124839002 LTPVS(ph)PESS(ph)STEEK ddPTM_HeLa_Curcumin_4h_R1 1 LTPVSPESSSTEEK 14 0 Q13501;E7EMC7;Q13501-2 Q13501 SQSTM1 Sequestosome-1 2 0 LT(0.083)PVS(0.885)PES(0.051)S(0.89)S(0.077)T(0.015)EEK 134.37 0.0022648 56274000 5365 4808.2 5139.1 4967.8 5902.1 6679 6112 8913.2 4927.1 4883.1 TRUE FALSE FALSE 4940.354589 5223.799383 5329.559567 4947.24456 5831.721312 5293.700112 6283.48627 11630.79365 4386.609457 5052.787362 0.977748366 1.033845086 1.054776143 0.979111965 1.154159258 1.047679179 1.243568316 2.301856939 0.868156355 1 12.30286375 -4.175852708 2.10207116 1.009448913 2.861881954 0.968495044 0.069355348 0.087936465 0.350693162 0.007997999 0.3320875 6.67E-05 4.175852708 1.852433041 up S(ph)KSMTSELEEMEYEQQPAPVPS(ph)MEK ddPTM_HeLa_Curcumin_4h_R1 1 SKSMTSELEEMEYEQQPAPVPSMEK 25 1 Q9Y566-2;Q9Y566-3;Q9Y566 Q9Y566-2 SHANK1 SH3 and multiple ankyrin repeat domains protein 1 2 0 S(0.73)KS(0.114)MT(0.114)S(0.068)ELEEMEY(0.053)EQQPAPVPS(0.921)MEK 41.597 0.0089736 0 464.18 462.09 313.98 303.39 425.7 594.41 513.49 503.6 410.9 422.12 TRUE FALSE FALSE 427.4396632 502.0310006 325.616375 302.1346526 420.6238055 471.1226656 527.8971474 657.1453217 365.825298 436.7886386 0.978596111 1.149368267 0.745478124 0.691718204 0.962991636 1.078605586 1.208587176 1.504492708 0.837533914 1 8.77079152 -4.428231625 1.520375126 0.960414358 1.608132505 0.657861559 0.132363556 0.408813292 1.097041089 0.01959026 0.358359909 3.73E-05 4.428231625 0.647718147 S(ph)KSPASVNGTPSSQLSTPK ddPTM_HeLa_Curcumin_4h_R1 1 SKSPASVNGTPSSQLSTPK 19 1 G5E9L9;Q8N568-2;Q8N568 G5E9L9 DCLK2 Serine/threonine-protein kinase DCLK2 1 0 S(0.5)KS(0.5)PASVNGTPSSQLSTPK 110.53 0.00020753 23940000 6340.7 4688.2 4985.8 5756.1 5519.1 6417.9 5756.1 6117.3 6381.4 5072.2 TRUE FALSE FALSE 5838.826904 5093.427118 5170.578134 5732.282783 5453.288337 5086.755195 5917.600674 7982.436609 5681.376385 5248.458572 1.112484137 0.970461526 0.985161274 1.092184058 1.039026652 0.969190311 1.127493071 1.520910663 1.082484754 1 12.35767806 -4.280433998 3.264748237 1.040702529 1.577853072 0.895748945 0.049835494 0.07719294 1.332041656 0.007832155 0.101680637 5.24E-05 4.280433998 0.537150543 S(ph)KSPLPPEEEAK ddPTM_HeLa_Curcumin_4h_R1 1 SKSPLPPEEEAK 12 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 0 S(0.644)KS(0.356)PLPPEEEAK 86.777 0.0079607 8653700 2450 2554.7 2187.6 2054 3045 2657.3 2172.9 2149.7 2206.7 2682.9 TRUE FALSE FALSE 2256.079915 2775.516884 2268.67438 2045.501092 3008.690364 2106.146026 2233.865726 2805.133634 1964.630531 2776.130575 0.812670677 0.99977894 0.817207375 0.736817321 1.0837712 0.758662451 0.804668824 1.010447296 0.707686644 1 11.43885971 -9.499315358 1.183071588 1.001683723 0.868848158 0 0.143156715 0.699187941 1.714950768 0.077410551 0.017811393 3.17E-10 9.499315358 -0.132835564 S(ph)KSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK ddPTM_HeLa_Curcumin_4h_R1 1 SKSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK 36 2 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 0 S(0.454)KS(0.454)PLPPEEEAKDEEEDQT(0.092)LVNLDTYTSDLHFQVSK 60.009 0.00011529 907440000 3109.1 2797.1 2327.6 2189.7 3477.9 4371.7 3060.1 2412.4 3245.1 3088.1 TRUE FALSE FALSE 2863.011454 3038.86886 2413.862904 2180.639602 3436.428314 3464.960141 3145.95817 3147.929655 2889.120649 3195.411245 0.895975896 0.951010254 0.755415412 0.682428468 1.075425994 1.084354994 0.984523721 0.985140695 0.904146736 1 11.6417859 S(ph)KSPPKVPIVIQDDSLPAGPPPQIR ddPTM_HeLa_Curcumin_4h_R1 1 SKSPPKVPIVIQDDSLPAGPPPQIR 25 2 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 0 S(0.5)KS(0.5)PPKVPIVIQDDSLPAGPPPQIR 84.025 7.61E-05 285850000 3932.9 3947 3958.8 3866.8 4085.7 4951.2 3652.9 4435.6 3887.9 3457.7 TRUE FALSE FALSE 3621.606815 4288.161093 4105.516611 3850.800206 4036.980696 3924.265308 3755.390543 5787.994021 3461.407097 3577.854818 1.012228556 1.198528535 1.147479934 1.076287441 1.128324346 1.096820723 1.049620718 1.61772747 0.967453201 1 11.80487913 -4.261431491 12.12534106 1.049299536 1.618111175 0.833685106 0.071863582 0.019037632 270.0176103 0.011386679 0.087711954 5.48E-05 4.261431491 0.568811639 MLTTVGPASSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 MLTTVGPASSSPK 13 0 A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-11;Q8IVL1;A0A0A0MTL4;Q8IVL1-4;Q8IVL1-3;Q8IVL1-2 A0A0A0MTE8 NAV2 Neuron navigator 2 1 0 MLTTVGPASS(0.184)S(0.816)PK;MLTTVGPASS(0.214)S(0.786)PK ; 158.01 0.00037458 46698000 7808.7 6148.5 7154 7362.9 6660.2 8470.2 6439.1 1189.3 8635.7 6407.7 TRUE FALSE FALSE 7190.633155 6679.948943 7419.133533 7332.434271 6580.781465 6713.385041 6619.763816 1551.912095 7688.385315 6630.367098 1.084500006 1.007477994 1.11896271 1.105886622 0.992521435 1.012520867 0.9984008 0.234061263 1.15957159 1 12.69487303 -4.258963556 4.543637162 1.042946736 0.179987635 0.950272837 0.056269052 0.025651062 1.354434401 0.006677195 0.070605746 5.51E-05 4.258963556 -0.862959101 down S(ph)KSTAALSGEAASCSPIIMPYK ddPTM_HeLa_Curcumin_4h_R1 1 SKSTAALSGEAASCSPIIMPYK 22 1 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;Q14244-2;Q14244-4 Q14244-3 MAP7 Ensconsin 1 0 S(0.326)KS(0.326)T(0.326)AALS(0.023)GEAASCSPIIMPYK 84.576 0.00027419 29963000 1969 1508.4 2176.6 1886.9 1810.2 3066.8 1958.4 2205.9 1969.8 2493.6 TRUE FALSE FALSE 1813.151572 1638.779375 2257.266711 1879.092508 1788.614547 2430.71111 2013.347433 2878.468755 1753.717868 2580.252414 0.702703178 0.635123667 0.874823989 0.72825918 0.693193634 0.942043924 0.780290882 1.115576422 0.679669112 1 11.33329649 -4.255865024 23.9899355 0.824721789 1.115576646 0.362054132 0.121429914 360.9941426 1553495.463 0.019491541 0.224254492 5.55E-05 4.255865024 0.290854857 S(ph)KSVPGLNVDMEEEEEEEDIDHLVK ddPTM_HeLa_Curcumin_4h_R1 1 SKSVPGLNVDMEEEEEEEDIDHLVK 25 1 Q96C24-2;Q96C24 Q96C24-2 SYTL4 Synaptotagmin-like protein 4 1 0 S(0.5)KS(0.5)VPGLNVDMEEEEEEEDIDHLVK 104.95 1.21E-07 12474000 5091.9 3313.4 4454 4401.6 4441.9 6048.6 4416.4 3672.3 5371.9 4591.7 TRUE FALSE FALSE 4688.870742 3599.795532 4619.069158 4383.387345 4388.933244 4794.052178 4540.312298 4791.967365 4782.61601 4751.261233 0.986868646 0.757650517 0.972177477 0.922573424 0.923740672 1.009006229 0.955601487 1.008567437 1.006599253 1 12.21409482 -7.488839266 24.98685431 0.994206832 0.934841804 0.154232566 0.066796992 614.9176147 451387.4712 0.011334089 0.012528465 3.24E-08 7.488839266 -0.059365028 SSTLSSSSMSLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SSTLSSSSMSLSPK 14 0 O15119-3;O15119-2;O15119 O15119-3 TBX3 T-box transcription factor TBX3 1 0 SSTLSSSSMSLS(1)PK;SSTLSSSSMS(0.025)LS(0.975)PK ; 214.48 9.12E-14 37841000 2130.97 1598.02 1735.23 2011.04 1465.19 2407.34 1718.67 638.12 2101.9 1821.03 TRUE FALSE FALSE 1962.301476 1736.145728 1799.53915 2002.718849 1447.718566 1908.030548 1766.891255 832.6798505 1871.326829 1884.310657 1.041389576 0.921369161 0.955011926 1.062838997 0.768301427 1.0125881 0.937685752 0.441901577 0.993109508 1 10.87982112 -4.258951968 3.709292026 0.992878903 0.381397101 0.789986885 0.080446493 0.085643225 2.184061289 0.01112278 0.143944755 5.51E-05 4.258951968 -0.611481801 down LCPSCPASS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 LCPSCPASSPK 11 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 LCPSCPAS(0.075)S(0.925)PK 158.56 0.00037743 37030000 5377.2 4672.9 5077.3 5209.8 4996.4 5043 3475.5 1027.3 5577.7 4169.8 TRUE FALSE FALSE 4951.588946 5076.804654 5265.469204 5188.243228 4936.821193 3997.024954 3573.013176 1340.519041 4965.840265 4314.70024 1.147609028 1.176629748 1.22035574 1.202457399 1.144186367 0.92637373 0.828102296 0.310686483 1.150911996 1 12.07504462 -4.258821428 1.376523657 1.10340034 1.07E-18 0.914873719 0.076921068 0.336697664 0.548497185 0.014182493 0.515633236 5.51E-05 4.258821428 -1.10340034 down S(ph)KTPVQAAAVSIVEKPVTR ddPTM_HeLa_Curcumin_4h_R1 2 SKTPVQAAAVSIVEKPVTR 19 2 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 0 S(0.5)KT(0.5)PVQAAAVSIVEKPVTR;S(0.5)KT(0.5)PVQAAAVSIVEKPVTR ; 81.643 0.0029552 56622000 3243.1 2870.1 3237.6 3040 3115.8 2823.2 2095.99 1299.55 3632.1 2815.8 TRUE FALSE FALSE 2986.405213 3118.178655 3357.588304 3027.421285 3078.64612 2237.636496 2154.797838 1695.776813 3233.667717 2913.64884 1.024970879 1.07019714 1.152365466 1.039048098 1.056629089 0.767984276 0.739553033 0.58201139 1.109834402 1 11.5086113 -5.048864338 2.075811513 1.032950354 0.645480068 0.88327164 0.061214297 0.082449133 0.681417246 0.00877997 0.033197427 8.94E-06 5.048864338 -0.387470286 S(ph)KY(ph)HGY(ph)PYSFLIK ddPTM_HeLa_Curcumin_4h_R1 1 SKYHGYPYSFLIK 13 1 Q13454-2 Q13454-2 3 0 S(0.987)KY(0.901)HGY(0.546)PY(0.542)S(0.023)FLIK 55.261 0.009332 0 444.08 666.3 474.15 599.49 504.11 626.87 378.35 389.01 601.24 487.97 TRUE FALSE FALSE 408.9305994 723.892003 491.7224161 597.0094692 498.0988175 496.8500957 388.9654827 507.6173582 535.2854762 504.9269212 0.809880761 1.433656976 0.973848681 1.18236807 0.986477046 0.984003971 0.770340155 1.005328369 1.060124651 1 8.979930789 -3.947235916 14.79761167 0.966225434 1.241114253 0 0.184056157 6374648.386 49815631.19 0.025990283 49793851.21 0.000112918 3.947235916 0.274888818 S(ph)LAS(ph)SHSRSRSPSSRS(ph)HS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SLASSHSRSRSPSSRSHSR 19 3 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 4 0 S(0.868)LAS(0.56)S(0.562)HS(0.008)RS(0.004)RS(0.004)PS(0.182)S(0.182)RS(0.814)HS(0.816)R 57.788 0.013826 27566000 2762.5 2586 2424.4 2360.2 2751 3112.5 2220.2 2412.3 2828.7 2276.5 TRUE FALSE FALSE 2543.84521 2809.522317 2514.250397 2350.434118 2718.196122 2466.932415 2282.492837 3147.799165 2518.398687 2355.608206 1.07991015 1.19269508 1.067346595 0.997803502 1.153925392 1.047259221 0.96896115 1.336299966 1.069107622 1 11.20188389 -13.52287875 0.150591178 0.627666866 1.130849944 0.059423336 0.101442683 101.4540272 1.040227188 11.10109643 0.219223266 3.00E-14 13.52287875 0.503183078 S(ph)LASIEAK ddPTM_HeLa_Curcumin_4h_R1 3 SLASIEAK 8 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 0 S(0.998)LAS(0.002)IEAK;S(0.699)LAS(0.301)IEAK;S(1)LASIEAK ;; 150.27 0.0019114 59121000 17099.2 7418.1 10739.7 11517.8 10792 26810.2 11063 7781.4 11158.7 8350.9 TRUE FALSE FALSE 15745.78028 8059.28751 11137.72273 11470.1424 10663.31245 21249.46231 11373.39801 10153.91304 9934.618528 8641.093153 1.822197724 0.932669903 1.288925201 1.327394832 1.23402355 2.459117374 1.316198981 1.175072744 1.149694645 1 13.07699812 -9.628401615 1.443774291 0.999808574 1.49689124 0.104188254 0.405452843 0.614299781 2.298899452 0.292769598 0.066678469 2.35E-10 9.628401615 0.497082667 S(ph)LDGAAAVDSADR ddPTM_HeLa_Curcumin_4h_R1 2 SLDGAAAVDSADR 13 0 A0A2R8Y4N6;A0A2R8YD30;A0A2U3TZH6;A0A3B3IU06;A0A2R8Y5Z6;A0A2R8Y5G2;A0A2R8Y570;A0A2R8YCW8;A0A2R8Y6G5;A0A3B3ITP0;A0A2R8YFR9;Q4VB86;A0A3B3IUD6;A0A2R8Y7Y3;A0A2R8Y7N0;A0A2R8Y420;P11171-3;P11171-7;P11171-5;P11171-4;P11171-6;P11171-2;P11171 A0A2R8Y4N6 EPB41 Protein 4.1 1 0 S(1)LDGAAAVDSADR;S(1)LDGAAAVDSADR ; 179.5 0.00016172 26416000 2432.1 1789.52 2068.18 2130.79 2496 3065 2445.9 1671.33 2235.1 1761.06 TRUE FALSE FALSE 2239.596719 1944.198135 2144.82857 2121.973356 2466.23683 2429.28445 2514.525371 2180.910823 1989.915122 1822.256704 1.229023723 1.066917812 1.177017796 1.164475538 1.353397041 1.333118679 1.379896348 1.196818658 1.092005927 1 10.83151049 -13.52287874 0.089992215 0.154681706 1.474851753 0.537837751 0.082037974 73.48125351 0.500839881 12.04410396 1.030364627 3.00E-14 13.52287874 1.320170047 S(ph)LDGLSEACGGAGSSGSAESGAGGGRR ddPTM_HeLa_Curcumin_4h_R1 1 SLDGLSEACGGAGSSGSAESGAGGGRR 27 1 Q96GS4 Q96GS4 C17orf59 Uncharacterized protein C17orf59 1 0 S(1)LDGLSEACGGAGSSGSAESGAGGGRR 59.732 0.0016763 6809000 841.44 611.03 694.47 564.81 721.77 1005.6 741.47 417.28 765.82 736.34 TRUE FALSE FALSE 774.8391361 663.8447105 720.2076691 562.4729659 713.1633642 797.0272246 762.2736526 544.5067511 681.811462 761.9277602 1.016945669 0.871269883 0.945244033 0.738223484 0.935998662 1.046066656 1.00045397 0.714643539 0.894850533 1 9.573510409 -7.268373309 24.40482144 1.008002125 0.900834134 0.068211387 0.104477698 457.8609038 1611495.005 0.016405647 0.018983857 5.39E-08 7.268373309 -0.107167991 S(ph)LDNNYSTPNER ddPTM_HeLa_Curcumin_4h_R1 1 SLDNNYSTPNER 12 0 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-25;O60716-26;O60716-27;O60716-29;H0YC95 O60716 CTNND1 Catenin delta-1 1 0 S(1)LDNNYSTPNER 151.3 0.00046778 17239000 2416.9 2017.4 2386.8 2325 1838.2 2655.4 2139.2 1683.3 2538 2160.9 TRUE FALSE FALSE 2225.599815 2191.775067 2475.256908 2315.379766 1816.280666 2104.640107 2199.220195 2196.530421 2259.58775 2235.991114 0.99535271 0.980225303 1.107006594 1.035504905 0.812293329 0.941256025 0.98355498 0.982352035 1.010553099 1 11.12669874 S(ph)LDS(ph)PTSSPGAGTR ddPTM_HeLa_Curcumin_4h_R1 1 SLDSPTSSPGAGTR 14 0 Q9P107;K7EJC2 Q9P107 GMIP GEM-interacting protein 2 0 S(0.925)LDS(0.429)PT(0.272)S(0.135)S(0.238)PGAGTR 98.253 0.014489 11192000 4111.7 3416.1 3515.4 3729.3 3614.4 3903 2907.1 1829.2 4091.9 3835 TRUE FALSE FALSE 3786.254606 3711.372462 3645.683816 3713.869145 3571.300641 3093.473804 2988.665402 2386.914659 3643.028807 3968.265965 0.954133276 0.935263033 0.918709544 0.935892195 0.899965041 0.779553042 0.753141404 0.601500676 0.918040484 1 11.95429301 -3.478966839 0.437507907 0.982409463 1.49E-17 0.936047519 0.029063992 1.060345641 0.083226285 0.005270425 0.628362142 0.00033192 3.478966839 -0.982409463 S(ph)LDSESISPGDFHR ddPTM_HeLa_Curcumin_4h_R1 2 SLDSESISPGDFHR 14 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 0 S(0.994)LDS(0.006)ESISPGDFHR;S(0.988)LDS(0.012)ESISPGDFHR ; 161.08 0.00013183 7393800 3236.7 2963.2 3027.7 2696.1 3685.3 4019.8 3149.3 1876.66 3887.9 2890.4 TRUE FALSE FALSE 2980.51178 3219.325804 3139.909225 2684.944253 3641.355204 3186.048168 3237.660882 2448.844995 3461.407097 2990.841185 0.996546321 1.076394768 1.04984151 0.897722108 1.217502027 1.065268254 1.082525177 0.818781354 1.15733564 1 11.54633559 -7.379342314 19.20741307 0.998365797 1.036082164 0 0.11374408 11.65540896 1855.551895 0.016463672 0.018826482 4.18E-08 7.379342314 0.037716368 HGS(ph)PEFCGILGER ddPTM_HeLa_Curcumin_4h_R1 1 HGSPEFCGILGER 13 0 Q15464 Q15464 SHB SH2 domain-containing adapter protein B 1 0 HGS(1)PEFCGILGER 146.27 0.00033887 29361000 5346.1 4490.1 4842 4749.1 4935.2 5395.7 3310 1082.3 4938.1 4240.3 TRUE FALSE FALSE 4922.950544 4878.204237 5021.448779 4729.449483 4876.350963 4276.570998 3402.869692 1412.288288 4396.402785 4387.650109 1.122001623 1.111803383 1.144450595 1.077900326 1.111380999 0.97468369 0.775556302 0.321878056 1.001994843 1 12.09923277 -4.258619699 1.435807986 1.074650996 0.007061232 0.959707189 0.047702681 0.196434101 0.354709528 0.008484593 0.300746919 5.51E-05 4.258619699 -1.067589764 down S(ph)LEDVTAEYIHK ddPTM_HeLa_Curcumin_4h_R1 1 SLEDVTAEYIHK 12 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3 RAI14 Ankycorbin 1 0 S(1)LEDVTAEYIHK 203.88 6.48E-09 10488000 1635.3 1047.6 1053 1211.7 1315.5 1472 1157.5 724 1172.6 948.19 TRUE FALSE FALSE 1505.864279 1138.149876 1092.025106 1206.686306 1299.813522 1166.690607 1189.976335 944.7442671 1043.968714 981.1395319 1.534811544 1.160028558 1.11301713 1.229882465 1.324799867 1.189117928 1.212851278 0.962905108 1.064036949 1 9.938314512 -4.065977455 1.934078029 1.241569643 0.752577921 0.158424777 0.144574406 2.392986839 5.916930478 0.028093424 2.481938932 8.59E-05 4.065977455 -0.488991722 S(ph)LEDVY(ph)Y(ph)SNLTSELKMTGLQGK ddPTM_HeLa_Curcumin_4h_R1 1 SLEDVYYSNLTSELKMTGLQGK 22 1 A0A2R8Y550;P0DPE8;A8MWV9 A0A2R8Y550 Putative uncharacterized protein LOC388820 3 0 S(0.94)LEDVY(0.713)Y(0.729)S(0.607)NLT(0.006)S(0.006)ELKMTGLQGK 47.52 0.0074673 0 908.13 1051.7 1004.8 884.37 1163.2 1459.5 853.69 949.51 1068.4 1096 TRUE FALSE FALSE 836.2505522 1142.604262 1042.038772 880.7107113 1149.3296 1156.783248 877.6422438 1239.011228 951.199193 1134.085918 0.737378481 1.007511197 0.918835826 0.776582001 1.013441381 1.020013765 0.773876326 1.092519718 0.838736446 1 10.14731423 -5.733259567 24.98718342 0.881415504 0.963817382 0.146854411 0.110988034 439.7151698 389895.5297 0.018476813 0.036948005 1.85E-06 5.733259567 0.082401878 GFS(ph)FVATGLMEDDGKPR ddPTM_HeLa_Curcumin_4h_R1 3 GFSFVATGLMEDDGKPR 17 1 E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2;Q5SVM6 E9PGT3 RPS6KA1 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 0 GFS(0.997)FVAT(0.003)GLMEDDGKPR;GFS(1)FVATGLMEDDGKPR;GFS(0.999)FVAT(0.001)GLMEDDGKPR ;; 109.77 0.00052226 17585200 2279.73 1680.86 1705.02 2096.93 2023.41 3511.08 3418.27 8115 1978.35 2399.74 TRUE FALSE FALSE 2099.286965 1826.146049 1768.209541 2088.253459 1999.282157 2782.84243 3514.177456 10589.22614 1761.329955 2483.130786 0.84541941 0.735420808 0.712088767 0.840976025 0.805145733 1.120699097 1.415220445 4.264465731 0.709318238 1 11.27794453 -4.175456776 2.192745059 0.889057649 5.676289939 0.983965636 0.130177202 0.076937411 0.34136111 0.019068616 0.775038138 6.68E-05 4.175456776 4.78723229 up S(ph)LEEEGQELPQSADVQR ddPTM_HeLa_Curcumin_4h_R1 2 SLEEEGQELPQSADVQR 17 0 P48681 P48681 NES Nestin 1 0 S(1)LEEEGQELPQSADVQR;S(1)LEEEGQELPQSADVQR ; 228.08 4.61E-22 8515600 1338.19 1309.34 1178.8 1027.48 1435.55 1498.14 1219.69 1644.84 1196.13 1202.84 TRUE FALSE FALSE 1232.270849 1422.513515 1222.487365 1023.22856 1418.432004 1187.408876 1253.911219 2146.344144 1064.917532 1244.6386 0.990063179 1.142912902 0.982202677 0.822108972 1.139633628 0.954019003 1.007450049 1.724471781 0.855603812 1 10.28151118 -4.261534739 7.710409911 0.999879592 1.731444228 0.836798129 0.097426957 0.022799304 14.37299319 0.010850781 0.086481988 5.48E-05 4.261534739 0.731564636 SRNEVVT(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 1 SRNEVVTPEK 10 1 A0A494C142;Q99728-3;Q99728-2;Q99728;A0A087X2H0 A0A494C142 BARD1 BRCA1-associated RING domain protein 1 1 0 SRNEVVT(1)PEK 89.747 0.016268 22281000 6088.9 5634.7 5574.7 6431.4 7186 6880.8 5525.4 1188.8 5962.4 5582.1 TRUE FALSE FALSE 5606.95714 6121.73836 5781.303286 6404.788571 7100.311643 5453.644517 5680.427853 1551.259647 5308.339637 5776.07756 0.970720542 1.059843518 1.000904719 1.108847398 1.229261825 0.944177854 0.98344037 0.268566277 0.91902153 1 12.4958744 -4.258546122 4.8332266 1.014657415 0.22635497 0.874913074 0.085706976 0.045151659 3.03286973 0.011783861 0.119272057 5.51E-05 4.258546122 -0.788302445 down S(ph)LEGEAAALR ddPTM_HeLa_Curcumin_4h_R1 2 SLEGEAAALR 10 0 P12036-2;P12036 P12036-2 NEFH Neurofilament heavy polypeptide 1 0 S(1)LEGEAAALR;S(1)LEGEAAALR ; 115.29 0.0059296 2025700 1090.31 796.63 906.44 1002.38 960.1 1267.31 992.07 966.86 996.22 873.88 TRUE FALSE FALSE 1004.010813 865.4871475 940.0334638 998.2324172 948.6514346 1004.45562 1019.904814 1261.651163 886.9371584 904.247265 1.11032773 0.957135488 1.039575678 1.103937447 1.049106225 1.110819639 1.127904782 1.395250184 0.980856888 1 9.820573519 -1.000002368 0.902957504 1.047538544 178.6351694 0.828923104 0.04849575 286.5311357 0.59122079 0.00801481 104905.0588 0.099999455 1.000002368 177.5876308 LS(ph)AETWDLLR ddPTM_HeLa_Curcumin_4h_R1 1 LSAETWDLLR 10 0 A0A0A0MSK4;A0A0A0MRC4;Q86YR5-4;Q86YR5 A0A0A0MSK4 GPSM1 G-protein-signaling modulator 1 1 0 LS(0.765)AET(0.235)WDLLR 111.52 0.0076856 0 499.23 429.93 434.34 625.01 601.19 640.85 443.67 171.8 585.08 512.59 TRUE FALSE FALSE 459.7154187 467.0912335 450.4370225 622.4238742 594.0212019 507.9304861 456.1181861 224.1810291 520.8981878 530.4024643 0.866729417 0.880635489 0.849236293 1.173493556 1.119944272 0.957632214 0.859947336 0.422662118 0.98208101 1 9.050943668 -4.258456477 2.759280988 0.956152672 0.319654763 0.728544315 0.100959168 0.204035336 2.07191038 0.015760693 0.294404156 5.51E-05 4.258456477 -0.636497908 down QSLPAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 QSLPASPR 8 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;H0YF21 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 QSLPAS(1)PR;QSLPAS(1)PR ; 144.55 0.0025439 689160000 4811.7 3618.5 4627.9 4193.6 4846.4 5552.3 3805.3 1437.43 5157.1 4082.1 TRUE FALSE FALSE 4430.848868 3931.267016 4799.414045 4176.247994 4788.609845 4400.690393 3912.066477 1875.69579 4591.379032 4223.952671 1.048981656 0.930708112 1.136237647 0.988706153 1.133679806 1.041841785 0.926162479 0.444061744 1.086986382 1 12.04437795 -4.25789058 2.774645474 1.03118522 0.331135372 0.89414606 0.061791033 0.090666251 0.93464985 0.007760195 0.144488514 5.52E-05 4.25789058 -0.700049848 down S(ph)LELNGAVEPSEGAPR ddPTM_HeLa_Curcumin_4h_R1 2 SLELNGAVEPSEGAPR 16 0 F5GYK2;Q9NRL3-2;Q9NRL3;Q9NRL3-3;M0R2A7;M0QYS2;M0R0P4;R4GN16 F5GYK2 STRN4 Striatin-4 1 0 S(1)LELNGAVEPSEGAPR;S(1)LELNGAVEPSEGAPR ; 152.25 0.00033751 36623000 1491.67 1428.53 1019.58 1449.24 1609.79 1780.02 1872.18 1576.02 1736.49 1232.42 TRUE FALSE FALSE 1373.602745 1552.005768 1057.366532 1443.243429 1590.594306 1410.823787 1924.708332 2056.541243 1546.001391 1275.246503 1.077127239 1.217024131 0.82914678 1.131736825 1.247283801 1.10631457 1.509283364 1.612661738 1.212315727 1 10.31656043 -4.355356652 0.801570491 1.040144076 1.954153357 0.668287624 0.12544015 0.752519447 0.377715805 0.017376902 0.592185039 4.41E-05 4.355356652 0.914009281 S(ph)LELSSLAGPGEDPLSADSLGKPTR ddPTM_HeLa_Curcumin_4h_R1 2 SLELSSLAGPGEDPLSADSLGKPTR 25 1 Q13615-3;Q13615-2;Q13615;G5E953 Q13615-3 MTMR3 Myotubularin-related protein 3 1 0 S(0.993)LELS(0.006)S(0.001)LAGPGEDPLSADSLGKPTR;S(0.911)LELS(0.07)S(0.019)LAGPGEDPLSADSLGKPTR ; 98.76 3.00E-06 40678000 3472.3 3130.43 2928.8 3030.7 3008.9 3641.5 2411.85 1393.02 3173.45 2439.89 TRUE FALSE FALSE 3197.463791 3401.01042 3037.343904 3018.159766 2973.020833 2886.211852 2479.52002 1817.745385 2825.330475 2524.675996 1.266484807 1.347107679 1.203062852 1.195464199 1.177585099 1.143200893 0.98211415 0.719991551 1.119086362 1 11.30188254 -4.358837325 1.867088642 1.160418227 0.631029823 0.726574817 0.087917903 0.386489703 1.603790272 0.017677824 0.330813817 4.38E-05 4.358837325 -0.529388404 S(ph)LEQDALR ddPTM_HeLa_Curcumin_4h_R1 1 SLEQDALR 8 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 S(1)LEQDALR 97.452 0.016544 2954400 1393.2 730.31 879.3 1252.2 1122.3 1470.7 688.15 442.29 1454.8 907.31 TRUE FALSE FALSE 1282.92675 793.4347422 911.8876315 1247.018728 1108.917305 1165.660242 707.4576369 577.1421849 1295.21208 938.838955 1.366503534 0.845123371 0.971292922 1.32825627 1.181158174 1.241597652 0.753545252 0.614740347 1.379589197 1 9.874733894 -4.664052442 4.705568462 1.153826662 0.649679571 0.561949511 0.170655959 0.120391893 4.432453822 0.025502975 0.102620838 2.17E-05 4.664052442 -0.504147091 S(ph)LESINSR ddPTM_HeLa_Curcumin_4h_R1 4 SLESINSR 8 0 P62888;A0A0C4DH44;E5RI99;E5RJH3 P62888 RPL30 60S ribosomal protein L30 1 0 S(1)LESINSR;S(1)LESINSR;S(0.996)LES(0.004)INSR;S(1)LESINSR ;;; 126.03 0.0063927 65781200 4167.45 3415.7 3547.31 3581.59 4146.59 4470.44 3156.88 2884.26 4364.35 3223.29 TRUE FALSE FALSE 3837.591935 3710.937888 3678.776429 3566.77033 4097.144622 3543.220352 3245.453556 3763.657597 3885.591724 3335.299088 1.150599042 1.112625222 1.102982471 1.069400445 1.228418956 1.062339616 0.973062227 1.128431813 1.164990492 1 11.70360042 -3.881827673 19.98863644 1.081202099 12.00129136 0 0.073317198 2065.19109 353667.3853 0.010667764 12850.36401 0.000131272 3.881827673 10.92008926 HSLS(ph)LDDIR ddPTM_HeLa_Curcumin_4h_R1 4 HSLSLDDIR 9 0 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 0 HS(0.229)LS(0.771)LDDIR;HS(0.015)LS(0.985)LDDIR;HS(0.08)LS(0.92)LDDIR;HS(0.027)LS(0.973)LDDIR ;;; 131.42 0.0017463 30651000 5229.63 4333.25 4686.37 4389.07 4505.49 4981.46 3042.19 1091.14 5140.06 3915.86 TRUE FALSE FALSE 4815.699267 4707.796821 4860.050995 4370.909191 4451.764974 3948.249043 3127.545664 1423.823563 4576.208278 4051.935844 1.188493464 1.161863614 1.199439276 1.078721224 1.098676076 0.974410552 0.771864557 0.351393412 1.129388138 1 11.98439562 -4.257646398 1.234408158 1.106207073 4.42E-19 0.94690928 0.056784967 0.330621077 0.413043378 0.012045008 0.466167213 5.53E-05 4.257646398 -1.106207073 down S(ph)LFSQRPQRMRS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SLFSQRPQRMRSR 13 3 Q9UBK2-9;Q9UBK2-4;Q9UBK2;Q9UBK2-3 Q9UBK2-9 PPARGC1A Peroxisome proliferator-activated receptor gamma coactivator 1-alpha 2 0 S(0.997)LFS(0.003)QRPQRMRS(1)R 74.338 0.0064449 0 2501.6 2769.4 2502.1 2759.8 2239.2 2551.4 2210.9 2387.1 3564.7 3294.2 TRUE FALSE FALSE 2303.59572 3008.774596 2594.830027 2748.380679 2212.499002 2022.21088 2272.931904 3114.915801 3173.661328 3408.673205 0.675804215 0.882682033 0.761243414 0.806290458 0.649079237 0.593254548 0.666808394 0.913820602 0.931054735 1 11.73499458 -9.45208496 0.781850862 1.032377411 0.732985364 0.433947769 0.099742837 0.593151434 0.529376545 0.119472996 0.019554815 3.53E-10 9.45208496 -0.299392046 ETPQGELRPEVVEDEVPRS(ph)PVAEEPGGGGSSSSEAK ddPTM_HeLa_Curcumin_4h_R1 1 ETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAK 36 2 Q7L8J4 Q7L8J4 SH3BP5L SH3 domain-binding protein 5-like 1 0 ETPQGELRPEVVEDEVPRS(0.915)PVAEEPGGGGS(0.008)S(0.029)S(0.036)S(0.012)EAK 67.153 3.85E-06 32093000 1177.6 1021.8 1061 1102 1103.1 1538.9 1578.9 2176.8 1326.8 1103.7 TRUE FALSE FALSE 1084.391717 1110.119839 1100.321593 1097.440216 1089.946253 1219.714793 1623.199685 2840.496299 1181.253359 1142.053493 0.949510443 0.97203839 0.963458892 0.960935913 0.954374081 1.068001456 1.421299173 2.487183234 1.03432402 1 10.15741451 -4.17539265 1.635022955 0.97160913 3.275106029 0.996086642 0.028497821 0.047594007 0.101954918 0.00387703 0.184117032 6.68E-05 4.17539265 2.303496899 up S(ph)LGEEIQESLK ddPTM_HeLa_Curcumin_4h_R1 1 SLGEEIQESLK 11 0 P48681 P48681 NES Nestin 1 0 S(1)LGEEIQESLK 177.42 0.00018829 3669600 1520.5 1451.8 1680.2 1419 1812 1917.3 1923.2 2148.4 1550.3 1402.8 TRUE FALSE FALSE 1400.150821 1577.287123 1742.46969 1413.128554 1790.393083 1519.630368 1977.159816 2803.43727 1380.235969 1451.547196 0.964592006 1.08662476 1.200422346 0.973532627 1.233437734 1.046903864 1.362105085 1.931344209 0.950872264 1 10.50337577 -1 0.738497941 1.007843348 153.4599225 0.888497352 0.094509648 70.55810449 0.299784082 0.015103148 17886.62723 0.1 1 152.4520792 S(ph)LGEQDQMTLRPPEKVDLEPLK ddPTM_HeLa_Curcumin_4h_R1 2 SLGEQDQMTLRPPEKVDLEPLK 22 2 P48681 P48681 NES Nestin 1 0 S(0.964)LGEQDQMT(0.036)LRPPEKVDLEPLK;S(0.977)LGEQDQMT(0.023)LRPPEKVDLEPLK ; 88.571 0.00030431 379190000 2343.72 1928.39 2121.53 1939.31 2022.23 2750 2098.6 2075.61 2370.7 2082.39 TRUE FALSE FALSE 2158.212089 2095.071439 2200.155768 1931.285649 1998.116228 2179.619001 2157.481068 2708.453934 2110.640141 2154.752898 1.001605377 0.972302412 1.021071034 0.896291009 0.927306435 1.011540118 1.001266118 1.256967301 0.979527696 1 11.07330672 -4.257986896 4.63160312 0.988540797 1.274201033 0.826098629 0.038078497 0.062590231 3.552209869 0.0055041 0.057922744 5.52E-05 4.257986896 0.285660237 S(ph)LGSAGPSGTLPR ddPTM_HeLa_Curcumin_4h_R1 2 SLGSAGPSGTLPR 13 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 0 S(0.998)LGS(0.001)AGPS(0.001)GTLPR;S(1)LGSAGPSGTLPR ; 140.33 0.00097906 50335000 1208.88 835.16 740.17 999.16 1257.04 1911.96 1269.51 797.08 1458.89 813.46 TRUE FALSE FALSE 1113.195872 907.347509 767.6013513 995.0257407 1242.050619 1515.397944 1305.129034 1040.106023 1298.853417 841.7276745 1.322513096 1.077958509 0.911935504 1.182123115 1.475596748 1.800342308 1.550535967 1.235679964 1.543080329 1 9.717209741 -5.749247988 4.223648694 1.129931772 1.545460175 0.384567695 0.209104765 0.126910338 5.20018207 0.027636604 0.054727159 1.78E-06 5.749247988 0.415528403 S(ph)LGSVQAPSYGAR ddPTM_HeLa_Curcumin_4h_R1 1 SLGSVQAPSYGAR 13 0 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 S(0.978)LGS(0.007)VQAPS(0.015)YGAR 168 0.00018754 51843000 1108.7 855.31 1137.8 1348.5 1108.9 1832.8 1056 553.03 1151.2 1096.8 TRUE FALSE FALSE 1020.945225 929.2391852 1179.967869 1342.920264 1095.677092 1452.65662 1085.628518 721.6463012 1024.91624 1134.913718 0.899579597 0.818775181 1.039698305 1.183279612 0.965427657 1.279970976 0.956573615 0.635860057 0.903078554 1 10.14836691 -10.02074997 2.538597499 1.00063887 0.965338183 0 0.17194019 2.558925131 29.98362878 0.141875775 0.024987552 9.53E-11 10.02074997 -0.035300687 EQLVDQGIMPPLKS(ph)PAAFHEQIK ddPTM_HeLa_Curcumin_4h_R1 1 EQLVDQGIMPPLKSPAAFHEQIK 23 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2S3;Q9ULH7-2;Q9ULH7-3 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2;Phosphatase and actin regulator 1 0 EQLVDQGIMPPLKS(1)PAAFHEQIK 65.833 0.00095622 10156000 982.21 635.42 965.07 844.92 655.82 1572.9 1748.6 2900.7 1113 996.25 TRUE FALSE FALSE 904.4670421 690.3428734 1000.836343 841.4239449 647.9997748 1246.66281 1797.66101 3785.110077 990.9066846 1030.869613 0.877382581 0.669670407 0.970866083 0.816227323 0.628595282 1.209331223 1.743829662 3.671764138 0.96123377 1 10.00964615 -4.173776241 1.563524129 0.895629091 5.155704956 0.974280196 0.137809238 0.148641129 0.28522092 0.021048321 1.027169561 6.70E-05 4.173776241 4.260075865 up S(ph)LIYTDTLVR ddPTM_HeLa_Curcumin_4h_R1 1 SLIYTDTLVR 10 0 Q5SYE7-2 Q5SYE7-2 NHSL1 NHS-like protein 1 1 0 S(0.629)LIYT(0.37)DT(0.001)LVR 97.779 0.014051 5795100 849.96 645.3 675.99 781.82 676.3 1047.7 641.37 478.4 517.02 791.73 TRUE FALSE FALSE 782.6847691 701.0768566 701.0427841 778.585036 668.2355642 830.39521 659.365116 624.2619577 460.3041995 819.2425586 0.95537611 0.855762252 0.855720661 0.950371813 0.815674866 1.013613369 0.804847245 0.761998936 0.561865585 1 9.678146853 -1 0.108573693 1.066276992 0.289899172 0 0.153622376 71.0934641 0.542272987 0.401896422 8.297315148 0.1 1 -0.77637782 S(ph)LKAVVT(ph)AAT(ph)MS(ph)NKFTQK ddPTM_HeLa_Curcumin_4h_R1 1 SLKAVVTAATMSNKFTQK 18 2 B7ZLU9;Q14833-3;Q14833-2;Q14833-4;Q14833-5;Q14833 B7ZLU9 GRM4 Metabotropic glutamate receptor 4 4 0 S(1)LKAVVT(0.99)AAT(0.945)MS(0.533)NKFT(0.533)QK 42.277 0.018858 55294000 2962.6 2334.5 2531.4 2792.1 2806.9 3398.8 2792.8 1182.5 2951.8 2048 TRUE FALSE FALSE 2728.107084 2536.283778 2625.215911 2780.54703 2773.429551 2693.850568 2871.158452 1543.038806 2627.994925 2119.167848 1.28734828 1.196830058 1.23879565 1.312093817 1.308735197 1.271183201 1.354851837 0.728134304 1.24010702 1 11.04928214 -9.358935014 0.999759125 0.995376332 1.230150083 0 0.184340192 0.691313271 1.197354727 0.119003063 0.028597522 4.38E-10 9.358935014 0.234773752 S(ph)LLDASEEAIK ddPTM_HeLa_Curcumin_4h_R1 1 SLLDASEEAIK 11 0 P18206;P18206-2 P18206 VCL Vinculin 1 0 S(1)LLDASEEAIK 210.93 6.43E-08 4118000 1916.8 1225.6 2075.5 1666.9 2550 2123.7 1955.8 2220.8 1465.2 1431.8 TRUE FALSE FALSE 1765.083257 1331.535403 2152.419856 1660.002809 2519.592915 1683.220681 2010.674484 2897.911697 1304.471226 1481.554943 1.191372122 0.898741831 1.452811362 1.120446337 1.700640889 1.136117623 1.357137981 1.955993404 0.880474417 1 10.53289641 -1 0.279160779 1.04887823 6.404951144 0.541329038 0.225229337 28.05327776 0.357384268 0.088825286 74.20013874 0.1 1 5.356072914 S(ph)LLDASEEAIKK ddPTM_HeLa_Curcumin_4h_R1 4 SLLDASEEAIKK 12 1 P18206;P18206-2 P18206 VCL Vinculin 1 0 S(1)LLDASEEAIKK;S(1)LLDASEEAIKK;S(0.998)LLDAS(0.002)EEAIKK;S(1)LLDASEEAIKK ;;; 162.72 0.00023835 157332000 8118.5 5801.12 8754.4 7643.5 10335 10467.7 9305.4 9446.5 5908 6416.9 TRUE FALSE FALSE 7475.912158 6302.542964 9078.845765 7611.873222 10211.76188 8296.581025 9566.48448 12326.69436 5259.907181 6639.886797 1.12590958 0.94919434 1.36731936 1.146385993 1.537942165 1.249506396 1.440760177 1.856461524 0.792168201 1 12.69694293 -1 0.276541562 1.017750324 6.564615064 0.724461722 0.156551287 16.57636778 0.21093666 0.056369315 44.83205044 0.1 1 5.54686474 S(ph)LLGIDTEDAIQGR ddPTM_HeLa_Curcumin_4h_R1 4 SLLGIDTEDAIQGR 14 0 P49454 P49454 CENPF Centromere protein F 1 0 S(1)LLGIDTEDAIQGR;S(1)LLGIDTEDAIQGR;S(0.992)LLGIDT(0.008)EDAIQGR;S(1)LLGIDTEDAIQGR ;;; 244.57 7.60E-29 53502000 3768.2 2832.09 3350.75 3336.98 3603.33 4581.7 3939.97 1443.46 3886.59 2916.28 TRUE FALSE FALSE 3469.942994 3076.88324 3474.931743 3323.172461 3560.362643 3631.403774 4050.514954 1883.564309 3460.240801 3017.620513 1.149893759 1.019638893 1.151546965 1.101255922 1.179857649 1.203399751 1.342287719 0.624188595 1.146678579 1 11.55919567 -9.437381161 1.009516574 0.995665722 1.114126275 0 0.183423062 1.499850025 2.566528387 0.135192639 0.029151639 3.65E-10 9.437381161 0.118460552 S(ph)LLRPGQAAELR ddPTM_HeLa_Curcumin_4h_R1 1 SLLRPGQAAELR 12 1 Q96BY6;F8WB48;F8WE73;Q96BY6-2 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 1 0 S(1)LLRPGQAAELR 65.695 0.018727 10454000 1788.5 1147.1 1806.3 1580.2 1186.8 2376.6 2752.4 1143.9 1581 1636.4 TRUE FALSE FALSE 1646.938338 1246.250213 1873.243067 1573.661551 1172.648185 1883.66637 2829.624936 1492.669844 1407.568255 1693.264778 0.972640758 0.736004332 1.106290694 0.929365313 0.692536808 1.112446437 1.671106003 0.881533629 0.83127475 1 10.72559187 -4.99667528 24.99286547 0.953273487 1.305183952 0.315220473 0.216793926 79.89354306 600557.6497 0.026267408 0.078250838 1.01E-05 4.99667528 0.351910465 HTGPNS(ph)PDTANDGFVR ddPTM_HeLa_Curcumin_4h_R1 5 HTGPNSPDTANDGFVR 16 0 P31943;G8JLB6;E9PCY7;D6RBM0;D6RIH9;D6RAM1;E5RGV0;D6R9T0;D6RFM3;D6RIT2;D6RIU0;D6RDU3;D6RJ04;H0YAQ2;E5RGH4;P55795;E7EQJ0 P31943;P55795;E7EQJ0 HNRNPH1;HNRNPH2 "Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2" 1 0 HTGPNS(1)PDTANDGFVR;HTGPNS(1)PDTANDGFVR;HT(0.003)GPNS(0.882)PDT(0.114)ANDGFVR;HTGPNS(1)PDTANDGFVR;HT(0.325)GPNS(0.637)PDT(0.038)ANDGFVR ;;;; 228.99 8.43E-22 2616938300 11645.17 9692.95 9584.36 10287.82 10471.69 14185.66 11661.77 16093.5 12599.7 9946.77 TRUE FALSE FALSE 10723.44251 10530.76541 9939.564813 10245.25173 10346.82194 11243.39421 11988.96788 21000.33406 11217.54443 10292.41952 1.041877713 1.023157421 0.965717031 0.99541723 1.005285678 1.09239564 1.164834747 2.040369034 1.089884105 1 13.32929455 -4.173622881 2.232476624 1.016804695 2.465976452 0.982762344 0.04000279 0.065286748 0.301878934 0.004959016 0.202094241 6.70E-05 4.173622881 1.449171756 up LDDGHLNNSLS(ph)SPVQADVYFPR ddPTM_HeLa_Curcumin_4h_R1 1 LDDGHLNNSLSSPVQADVYFPR 22 0 F8WF17;B9A055;U3KQ88;Q3ZCW2 F8WF17 LGALSL Galectin;Galectin-related protein 1 0 LDDGHLNNS(0.023)LS(0.573)S(0.404)PVQADVYFPR 90.062 0.00016283 6573100 1065.2 806.96 763.42 634.88 622.65 1404.5 1059.9 2317.3 988.2 773.27 TRUE FALSE FALSE 980.888296 876.7100267 791.7130168 632.2530348 615.2253054 1113.190868 1089.637941 3023.834102 879.7969324 800.1410749 1.225894191 1.095694315 0.989466785 0.790176951 0.768896042 1.391243248 1.361807281 3.779126203 1.099552266 1 9.644110577 -4.172053089 2.374388989 1.0671325 4.854740248 0.953719738 0.179330713 0.128293031 0.692389001 0.027246038 1.087155245 6.73E-05 4.172053089 3.787607748 up TTTS(ph)PFFSEDTFR ddPTM_HeLa_Curcumin_4h_R1 1 TTTSPFFSEDTFR 13 0 A0A5F9ZGT0;H0Y9K9;G5E9Z1;A0A590UJE4;A0A494C0H4;H0Y9M2;Q17R98-3;Q17R98-2;Q17R98;A0A5F9ZHK5 A0A5F9ZGT0 ZNF827 Zinc finger protein 827 1 0 T(0.003)T(0.003)T(0.023)S(0.784)PFFS(0.187)EDTFR 104.59 0.0052065 24154000 2827 2440.7 2442.7 2644.4 2931 3146.2 2022.9 446.57 2935.9 2502.5 TRUE FALSE FALSE 2603.239967 2651.663232 2533.228611 2633.458173 2896.049739 2493.642655 2079.65713 582.7271372 2613.839115 2589.461689 1.005320904 1.024021033 0.978283873 1.016990591 1.118398373 0.962996543 0.803123344 0.225037945 1.00941409 1 11.3384365 -4.257484326 2.039202702 1.010294756 7.34E-19 0.975377134 0.037882442 0.077493743 0.340926683 0.005463673 0.14529741 5.53E-05 4.257484326 -1.010294756 down RASGQAFELILS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 RASGQAFELILSPR 14 1 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 1 0 RASGQAFELILS(1)PR;RASGQAFELILS(1)PR ; 114.28 0.0010882 112053000 4229.1 3198.24 3584.02 3621.9 2960.18 5450.3 4720.3 7151.8 4001.3 3879.7 TRUE FALSE FALSE 3894.362272 3474.681615 3716.846934 3606.913537 2924.881787 4319.846342 4852.738914 9332.350897 3562.367401 4014.519286 0.970069389 0.865528689 0.925851059 0.898467109 0.728575846 1.076055695 1.208797011 2.324649661 0.887370852 1 11.97101153 -4.171885399 2.024138679 0.951553891 2.947162926 0.956304509 0.089832193 0.145155011 0.521297817 0.013251514 0.576103632 6.73E-05 4.171885399 1.995609034 up DASSS(ph)PASTASSASSTSLK ddPTM_HeLa_Curcumin_4h_R1 2 DASSSPASTASSASSTSLK 19 0 A0A669KBK8;Q04724 A0A669KBK8 TLE1 Transducin-like enhancer protein 1 1 0 DAS(0.008)S(0.047)S(0.946)PASTASSASSTSLK;DASS(0.001)S(0.999)PASTASSASSTSLK ; 294.05 3.18E-83 59625000 7691.6 6368.7 6352.8 6347.2 6736.5 8403 6204.8 2209 7588 6186.9 TRUE FALSE FALSE 7082.801744 6919.18205 6588.240356 6320.936968 6656.171637 6660.123079 6378.889989 2882.513931 6755.615384 6401.894314 1.106360305 1.080802292 1.029107953 0.987354158 1.039719075 1.040336305 0.996406638 0.450259531 1.055252563 1 12.64428315 -4.257453423 3.907752824 1.04562029 0.391285087 0.966359498 0.032950009 0.041612408 1.265391922 0.006274669 0.077747496 5.53E-05 4.257453423 -0.654335203 down S(ph)LPEEDVAEIQHAEEFLIKPESK ddPTM_HeLa_Curcumin_4h_R1 5 SLPEEDVAEIQHAEEFLIKPESK 23 1 O60832;H7C2Q9;H7C0M1;C9IYT0;O60832-2 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 1 0 S(0.997)LPEEDVAEIQHAEEFLIKPES(0.003)K;S(1)LPEEDVAEIQHAEEFLIKPESK;S(1)LPEEDVAEIQHAEEFLIKPESK;S(1)LPEEDVAEIQHAEEFLIKPESK;S(1)LPEEDVAEIQHAEEFLIKPESK ;;;; 151.41 5.83E-07 423413800 11381.5 9340.14 9109.9 9443.1 9600.9 13554.1 9135.89 5160.41 11651 7936.14 TRUE FALSE FALSE 10480.64227 10147.46008 9447.520908 9404.026954 9486.415538 10742.82687 9392.218485 6733.795253 10372.91445 8211.920274 1.276271799 1.235698807 1.150464275 1.145167834 1.155200638 1.30819912 1.143729867 0.820002512 1.263153331 1 13.00350391 -4.263867992 6.279030449 1.156662851 0.812644906 0.586725132 0.089218699 0.08814421 19.022064 0.015855407 0.129402433 5.45E-05 4.263867992 -0.344017945 S(ph)LPELDRDKSDSDTEGLLFSR ddPTM_HeLa_Curcumin_4h_R1 1 SLPELDRDKSDSDTEGLLFSR 21 2 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 S(0.88)LPELDRDKS(0.097)DS(0.015)DT(0.008)EGLLFSR 48.919 0.010729 6875000 3404.6 3139.5 3207.5 3298.6 3249.5 4389 3762.1 4760.5 3936.7 3518 TRUE FALSE FALSE 3135.122317 3410.864391 3326.372772 3284.951267 3210.751835 3478.671926 3867.654401 6211.954535 3504.853859 3640.250238 0.861238133 0.936986242 0.913775854 0.902397102 0.882014044 0.955613405 1.062469377 1.706463602 0.96280575 1 11.82982191 -4.218073535 2.378436926 0.926801334 1.945117619 0.973444716 0.038462113 0.099761822 0.609888303 0.007572573 0.217361388 6.05E-05 4.218073535 1.018316284 S(ph)LPPGLLR ddPTM_HeLa_Curcumin_4h_R1 3 SLPPGLLR 8 0 Q14432 Q14432 PDE3A "cGMP-inhibited 3,5-cyclic phosphodiesterase A" 1 0 S(1)LPPGLLR;S(1)LPPGLLR;S(1)LPPGLLR ;; 116.37 0.0094078 69939000 4835.9 3894.5 4801.5 4325.4 4548.4 5862.2 4492.2 2268.03 4801.3 3852.9 TRUE FALSE FALSE 4453.133412 4231.123226 4979.447814 4307.502641 4494.163301 4646.313639 4618.239042 2959.541906 4274.609402 3986.787988 1.116972717 1.061286238 1.248987362 1.080444371 1.127264182 1.165427821 1.158385913 0.742337419 1.07219381 1 11.96101117 -1.158026797 15.77587575 1.073432374 0.005389427 0 0.129037924 0 0 0.01618412 0 0.069498143 1.158026797 -1.068042947 KQETAAVCGET(ph)DEEAGES(ph)GGEGIFR ddPTM_HeLa_Curcumin_4h_R1 1 KQETAAVCGETDEEAGESGGEGIFR 25 1 Q9ULL5;Q9ULL5-2;A0A3Q5ADB5 Q9ULL5 PRR12 Proline-rich protein 12 2 0 KQET(0.005)AAVCGET(0.995)DEEAGES(1)GGEGIFR 57.851 0.0047584 22526000 4286.9 3465.3 3778.1 3999.1 3905.3 5283.7 3513.4 920.76 4228.6 4193.6 TRUE FALSE FALSE 3947.587341 3764.825091 3918.11971 3982.552784 3858.731848 4187.80106 3611.976548 1201.495485 3764.733159 4339.327288 0.909723346 0.8676057 0.902932517 0.917781149 0.889246556 0.96508071 0.832381682 0.276885196 0.867584515 1 12.08325569 -4.257426164 2.94819704 0.938716572 0.161406055 0.947335374 0.044566501 0.066631985 0.820515506 0.007084926 0.122650951 5.53E-05 4.257426164 -0.777310516 down S(ph)LPTTVPES(ph)PNYR ddPTM_HeLa_Curcumin_4h_R1 3 SLPTTVPESPNYR 13 0 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50;H0YC33 Q6PKG0 LARP1 La-related protein 1 2 0 S(1)LPTTVPES(1)PNYR;S(1)LPTTVPES(1)PNYR;S(1)LPTTVPES(1)PNYR ;; 204.23 1.55E-08 4206225000 15097.2 15429.1 14437.3 15611.8 14652.2 17205.4 14092.3 8435.2 17062.2 14261.5 TRUE FALSE FALSE 13902.24069 16762.72265 14972.35904 15547.20251 14477.48208 13636.8061 14487.69201 11007.05365 15190.51935 14757.08606 0.942072211 1.135910069 1.01458777 1.053541495 0.9810529 0.924085286 0.981744766 0.745882595 1.029371197 1 13.84912025 -3.655622473 1.414850739 0.99211727 2.41E-17 0.632657832 0.058487739 3.25582788 1.706074021 0.008915266 7.014829161 0.000220992 3.655622473 -0.99211727 S(ph)LPTTVPESPNYR ddPTM_HeLa_Curcumin_4h_R1 4 SLPTTVPESPNYR 13 0 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50;H0YC33 Q6PKG0 LARP1 La-related protein 1 1 0 S(1)LPTTVPESPNYR;S(1)LPTTVPESPNYR;S(1)LPTTVPESPNYR;S(0.992)LPT(0.007)T(0.001)VPESPNYR ;;; 220.37 8.86E-14 1409250000 5114.16 4700.59 4975.74 5027.89 4648.01 5660.54 3984.72 4342.56 5443.89 4787.19 TRUE FALSE FALSE 4709.36884 5106.888054 5160.145302 5007.085923 4592.585516 4486.480197 4096.520519 5666.586553 4846.708887 4953.544496 0.950706881 1.03095633 1.041707671 1.01080871 0.927131172 0.905711092 0.82698773 1.143945827 0.978432492 1 12.2742455 -5.753566437 24.60308582 0.988245959 0.938859014 0.067642138 0.079149964 295.0183207 921928.2385 0.010916523 0.021512068 1.76E-06 5.753566437 -0.049386945 S(ph)LPVSVPVWGFK ddPTM_HeLa_Curcumin_4h_R1 4 SLPVSVPVWGFK 12 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 0 S(1)LPVSVPVWGFK;S(1)LPVSVPVWGFK;S(1)LPVSVPVWGFK;S(1)LPVSVPVWGFK ;;; 225.97 8.20E-19 3143643240 10847.44 8353.28 9345.83 8887.72 9070.04 19165.11 12778.74 9189.36 10893.94 10629.9 TRUE FALSE FALSE 9988.853678 9075.300302 9692.194681 8850.94497 8961.885697 15190.05015 13137.27705 11991.15356 9698.902037 10999.28823 0.908136369 0.825080688 0.881165624 0.804683429 0.814769602 1.381003009 1.194375197 1.09017541 0.881775423 1 13.42512255 -5.268112896 24.99975559 0.919893891 1.219103607 0.735278563 0.092880392 240.9129298 902488.9884 0.01478579 0.033792512 5.39E-06 5.268112896 0.299209716 S(ph)LQEEHVAVAQLR ddPTM_HeLa_Curcumin_4h_R1 2 SLQEEHVAVAQLR 13 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 S(1)LQEEHVAVAQLR;S(1)LQEEHVAVAQLR ; 172.42 9.60E-05 64924000 4816.2 3169.9 3891.1 4292.9 4379 6830.3 5788.7 1810.53 4063.4 3340.3 TRUE FALSE FALSE 4434.992688 3443.892031 4035.307589 4275.137117 4326.783285 5413.618787 5951.115343 2362.552262 3617.655186 3456.375176 1.283134053 0.996388371 1.167496983 1.236884568 1.25182686 1.56627059 1.721779332 0.683534669 1.046661604 1 11.75504411 -5.896397762 2.038913716 1.127507061 1.360537922 0.108691947 0.265341176 0.497283462 4.186071829 0.039752363 0.08169221 1.27E-06 5.896397762 0.233030861 QILIACS(ph)PVSSVR ddPTM_HeLa_Curcumin_4h_R1 2 QILIACSPVSSVR 13 0 E9PRB3;J3KP30;Q5QJE6 E9PRB3 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 0 QILIACS(0.997)PVS(0.002)S(0.001)VR;QILIACS(0.962)PVS(0.029)S(0.009)VR ; 148.85 0.00060361 428570000 6632.6 4728.7 4472.2 4791.1 4901.6 6268.6 5058.6 1403.13 5553.4 4980.7 TRUE FALSE FALSE 6107.622711 5137.427757 4637.943666 4771.275698 4843.151621 4968.421698 5200.530701 1830.937878 4944.205914 5153.778954 1.185076575 0.996827338 0.899911251 0.925781983 0.939728239 0.96403469 1.009071353 0.355261235 0.959336044 1 12.33141495 -4.257285602 4.64511939 1.039156895 0.311325579 0.809429529 0.088782904 0.071132773 4.077025536 0.015886716 0.168142048 5.53E-05 4.257285602 -0.727831316 down EPALPLEPDSGGNTS(ph)PGVTANGEAR ddPTM_HeLa_Curcumin_4h_R1 2 EPALPLEPDSGGNTSPGVTANGEAR 25 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;Q5VY93 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 0 EPALPLEPDSGGNT(0.001)S(0.999)PGVTANGEAR;EPALPLEPDSGGNT(0.393)S(0.607)PGVTANGEAR ; 239.57 4.56E-44 56324000 9142.7 7471.2 7327 7836.7 8034.6 10984.4 9754.2 13107.6 8669 7932.7 TRUE FALSE FALSE 8419.045648 8116.977237 7598.545065 7804.273812 7938.792643 8706.11162 10027.8766 17104.0469 7718.032389 8208.360735 1.025667112 0.988867022 0.925707984 0.950771301 0.967159327 1.060639499 1.221666167 2.083734798 0.940264766 1 13.00287842 -4.170550719 1.95927562 0.997894693 2.592501352 0.985819601 0.039585693 0.083941671 0.277055055 0.005831035 0.259997277 6.75E-05 4.170550719 1.594606659 up S(ph)LS(ph)PVAAPPLREPR ddPTM_HeLa_Curcumin_4h_R1 1 SLSPVAAPPLREPR 14 1 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 2 0 S(1)LS(1)PVAAPPLREPR 86.777 0.0094111 7530000 2912.6 2506.5 3168.1 2487.9 2256.7 2805 2830.2 972.5 2927.1 2721.9 TRUE FALSE FALSE 2682.064637 2723.150691 3285.512573 2477.605729 2229.790326 2223.211381 2909.607795 1269.010773 2606.004453 2816.485822 0.952273438 0.966861139 1.166529065 0.879679816 0.791692367 0.789356496 1.033063178 0.450565298 0.925268089 1 11.45968049 -6.008177277 7.166212692 0.990343849 0.792224263 0.362452652 0.145654232 0.123175311 38.37615536 0.01956221 0.034091194 9.81E-07 6.008177277 -0.198119586 S(ph)LSDS(ph)ESDDSKSK ddPTM_HeLa_Curcumin_4h_R1 1 SLSDSESDDSKSK 13 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 2 0 S(0.734)LS(0.266)DS(0.784)ES(0.198)DDS(0.016)KS(0.002)K 148.85 0.00241 42965000 6662.9 4930.2 5380.8 5080.1 4645.8 5768.1 4478.2 2502.5 7138.6 5838.4 TRUE FALSE FALSE 6135.524434 5356.344519 5580.217181 5059.079892 4590.401869 4571.73104 4603.84624 3265.50073 6355.51344 6041.283965 1.015599411 0.886623531 0.923680663 0.837417993 0.759838785 0.756748245 0.762064201 0.540530912 1.052013691 1 12.56063949 -4.694647969 0.361473551 1.022606077 0.379396628 0.898934768 0.046924574 0.989204366 0.112082868 0.016147378 0.263306344 2.02E-05 4.694647969 -0.643209449 S(ph)LSDSES(ph)DDSKSK ddPTM_HeLa_Curcumin_4h_R1 3 SLSDSESDDSKSK 13 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 2 0 S(0.999)LS(0.002)DS(0.082)ES(0.917)DDSKSK;S(0.957)LS(0.043)DS(0.432)ES(0.464)DDS(0.104)KS(0.001)K;S(0.882)LS(0.118)DS(0.067)ES(0.906)DDS(0.026)KS(0.001)K ;; 212.11 2.09E-40 50342000 14726.4 11040.1 11777.7 11905.6 10297.5 13534.2 9697.7 8277.8 14271.6 12135.6 TRUE FALSE FALSE 13560.7899 11994.35705 12214.19192 11856.33778 10174.70904 10727.05436 9969.791362 10801.66311 12706.04119 12557.3112 1.079911909 0.955169213 0.972675737 0.944178065 0.810261757 0.854247712 0.793943162 0.860189171 1.011844095 1 13.61623996 -6.176009025 1.119528561 1.034869208 0.822882256 0.824322697 0.037525803 0.138793461 0.343397818 0.007268375 0.015561634 6.67E-07 6.176009025 -0.211986953 S(ph)LSDSESDDS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 2 0 S(0.587)LS(0.416)DS(0.214)ES(0.025)DDS(0.759)K 125.84 0.0082082 17530000 5530 5303.6 5727 5475.4 6074.1 5746.7 4429.8 2516.8 5796.6 5104.8 TRUE FALSE FALSE 5092.294665 5762.019552 5939.247658 5452.744246 6001.670325 4554.769641 4554.088266 3284.160734 5160.727482 5282.19142 0.964049626 1.090838838 1.124390842 1.032288271 1.136208412 0.86228788 0.862158885 0.62174209 0.97700501 1 12.36692087 -4.379337758 1.381221327 1.01254703 0.524753338 0.760501769 0.071817895 0.422207988 0.82720266 0.011365144 0.267894138 4.18E-05 4.379337758 -0.487793692 CS(ph)PTVAFVEFPSSPQLK ddPTM_HeLa_Curcumin_4h_R1 1 CSPTVAFVEFPSSPQLK 17 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 CS(0.951)PT(0.049)VAFVEFPSSPQLK 154.46 0.00018344 80609000 752.98 850.59 863.34 976.08 965.49 1128.1 1222.6 2757.9 668.91 671.27 TRUE FALSE FALSE 693.3808385 924.1112094 895.3361399 972.0412396 953.9771623 894.1193437 1256.902866 3598.771014 595.5322465 694.5965825 0.998249712 1.330428673 1.289001648 1.399432799 1.373426225 1.287249846 1.809543694 5.181095192 0.857378601 1 9.440031502 -4.166366375 2.09110567 1.108582141 7.036834068 0.974773043 0.191077517 0.113445919 0.436245423 0.031114906 1.37790946 6.82E-05 4.166366375 5.928251926 up S(ph)LSDSESDDSKS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SLSDSESDDSKSK 13 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 2 0 S(0.97)LS(0.033)DS(0.209)ES(0.069)DDS(0.016)KS(0.703)K 111.81 0.01462 18330000 3001.6 2210.6 2336.5 2523.7 2235.9 3653.9 2130.2 2246.3 2979.2 3040.6 TRUE FALSE FALSE 2764.020193 2401.674414 2423.092745 2513.257598 2209.238353 2896.039952 2189.967679 2931.186529 2652.389214 3146.260624 0.87850961 0.763342488 0.77015004 0.798807823 0.702179068 0.920470456 0.696054123 0.931641361 0.843029085 1 11.61942247 -8.053891191 0.845827158 0.981049142 0.793619245 0.171627057 0.087873053 0.283040447 0.437110106 0.022530594 0.01633983 8.83E-09 8.053891191 -0.187429896 S(ph)LSDSESDDSKSK ddPTM_HeLa_Curcumin_4h_R1 1 SLSDSESDDSKSK 13 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 0 S(0.992)LS(0.007)DS(0.001)ESDDSKSK 148.85 0.0057662 66709000 5435.9 4258.2 4339.8 4347.3 3351.5 6365.6 4708.3 8666.3 5767.9 4935.7 TRUE FALSE FALSE 5005.642779 4626.259834 4500.636806 4329.312024 3311.535551 5045.302805 4840.402226 11308.61498 5135.175801 5107.215208 0.980111974 0.905828254 0.881231086 0.847685451 0.64840337 0.987877464 0.947757639 2.214242893 1.005474724 1 12.31832114 -4.261412676 9.053226233 0.942639958 2.219710274 0.931650552 0.105549391 0.016148099 26.86346017 0.015990366 0.124989733 5.48E-05 4.261412676 1.277070316 S(ph)LSGSS(ph)PCPK ddPTM_HeLa_Curcumin_4h_R1 3 SLSGSSPCPK 10 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(1)LSGS(0.025)S(0.975)PCPK;S(1)LSGS(0.007)S(0.993)PCPK;S(1)LS(0.039)GS(0.168)S(0.793)PCPK ;; 163.45 0.0014202 413502000 25058.9 21981.5 20848.8 22586 21506.1 25021.5 17939.7 15478.3 24279.9 21127 TRUE FALSE FALSE 23075.46162 23881.48291 21621.47487 22492.54512 21249.6538 19831.75885 18443.0397 20197.56242 21616.45572 21861.16168 1.055545994 1.092416005 0.989035953 1.028881514 0.972027659 0.907168573 0.843644083 0.923901608 0.988806361 1 14.41608245 -5.40899985 1.954974625 1.029903219 0.881264525 0.746133707 0.035053325 0.120646765 0.893076911 0.00527929 0.014851555 3.90E-06 5.40899985 -0.148638694 S(ph)LSNPDIASETLTLLSFLR ddPTM_HeLa_Curcumin_4h_R1 1 SLSNPDIASETLTLLSFLR 19 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 0 S(0.569)LS(0.43)NPDIAS(0.001)ETLTLLSFLR 101.23 0.00090364 18443000 552.62 624.15 501.47 669.42 639.57 461.13 326.63 376.63 523.48 454.33 TRUE FALSE FALSE 508.8795439 678.0987448 520.0549193 666.6501174 631.9435455 365.48644 335.7943587 491.4627532 466.0555537 470.1179337 1.082450822 1.442401356 1.106222252 1.418048684 1.344223439 0.777435647 0.714276854 1.045403117 0.991358807 1 8.876878906 -5.238520171 24.71908716 1.122759127 0.832562328 0.396855517 0.183024384 669.7270919 722320.2514 0.028189487 0.071811274 5.77E-06 5.238520171 -0.290196799 S(ph)LSPGGAALGYR ddPTM_HeLa_Curcumin_4h_R1 4 SLSPGGAALGYR 12 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 0 S(0.987)LS(0.013)PGGAALGYR;S(1)LSPGGAALGYR;S(0.999)LS(0.001)PGGAALGYR;S(0.996)LS(0.004)PGGAALGYR ;;; 216.91 2.87E-13 1115700000 16226.4 13847.5 14395.2 13835.2 14571.3 17199.3 13217.8 9294.4 16584.9 14184.8 TRUE FALSE FALSE 14942.06332 15044.4162 14928.69878 13777.95361 14397.54676 13631.9713 13588.65589 12128.21977 14765.57796 14677.72074 1.018009784 1.024983133 1.017099251 0.938698443 0.980911615 0.9287526 0.925801501 0.826301303 1.005985754 1 13.84134033 -2.523470597 0.459447728 1.010941472 7.30E-17 0.873919546 0.02101645 4.5951219 0.188997543 0.004532661 3.603171977 0.002995914 2.523470597 -1.010941472 S(ph)LSPIIGK ddPTM_HeLa_Curcumin_4h_R1 1 SLSPIIGK 8 0 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-4;H7C2K6;X6RC15;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 S(0.716)LS(0.284)PIIGK 102.07 0.013843 461680000 8059.5 6964.6 8049.4 6570.9 7232.8 6480.2 4599.5 2646.3 7824.3 5689.1 TRUE FALSE FALSE 7421.582071 7566.58899 8347.717845 6543.711357 7146.553584 5136.133473 4728.549591 3453.144688 6965.993865 5886.795802 1.26071675 1.285349322 1.418041007 1.111591361 1.213997194 0.872483715 0.803246749 0.586591552 1.183325208 1 12.52326687 -4.888241177 1.617013474 1.166377578 0.623877317 0.761681849 0.118358567 0.215152225 0.997450457 0.021929788 0.125648315 1.29E-05 4.888241177 -0.542500261 S(ph)LSPQEDALTGSR ddPTM_HeLa_Curcumin_4h_R1 1 SLSPQEDALTGSR 13 0 Q96EN8 Q96EN8 MOCOS Molybdenum cofactor sulfurase 1 0 S(1)LSPQEDALTGSR 118.16 0.0026763 4285100 1449.6 1112.5 1405.9 1446.5 1539.7 1750.2 1340 1281.1 1735 1429.7 TRUE FALSE FALSE 1334.86263 1208.659543 1458.003891 1440.514766 1521.340083 1387.188791 1377.596794 1671.701493 1544.674841 1479.381969 0.902311005 0.817003025 0.985549318 0.973727406 1.028361921 0.937681289 0.931197502 1.129999911 1.044135236 1 10.53077888 -6.55426585 24.98993887 0.940360951 0.992971237 0.116524662 0.076330564 349.8375283 278534.1935 0.01168494 0.016525089 2.79E-07 6.55426585 0.052610286 S(ph)LSPSVR ddPTM_HeLa_Curcumin_4h_R1 1 SLSPSVR 7 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 0 S(0.672)LS(0.328)PSVR 110.12 0.015982 26187000 3017.4 2614.3 2456.6 2360.9 2674.9 2526.9 1875.5 1050.9 2739.8 2141.6 TRUE FALSE FALSE 2778.569606 2840.268443 2547.643757 2351.131221 2643.003565 2002.792456 1928.121482 1371.314572 2439.250795 2216.020441 1.253855585 1.281697764 1.149648131 1.060970007 1.192680138 0.903778873 0.870082896 0.618818557 1.10073479 1 11.11375547 -4.555599947 1.097347688 1.138777624 0.523563 0.783922856 0.089405748 0.49263159 0.656152271 0.017764296 0.308893666 2.78E-05 4.555599947 -0.615214624 S(ph)LSPVAAPPLR ddPTM_HeLa_Curcumin_4h_R1 1 SLSPVAAPPLR 11 0 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 0 S(0.612)LS(0.388)PVAAPPLR 107.11 0.008745 0 1507.7 1725.3 1538.6 1471.7 1807.6 1909.5 1516.9 1545.1 1501.7 1333.2 TRUE FALSE FALSE 1388.363954 1874.427244 1595.621869 1465.610495 1786.045551 1513.448175 1559.460131 2016.193877 1336.967267 1379.528601 1.006404618 1.35874475 1.156642833 1.0623995 1.29467816 1.097076331 1.130429721 1.461509298 0.969147915 1 10.42995965 -1 0.124968696 0.899722908 2.234847062 0.389039344 0.123126502 64.77200911 0.551419982 0.488406121 15.20292341 0.1 1 1.335124154 S(ph)LSSS(ph)PVKK ddPTM_HeLa_Curcumin_4h_R1 1 SLSSSPVKK 9 1 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 2 0 S(0.999)LS(0.008)S(0.247)S(0.746)PVKK 118.23 0.01027 94044000 9805.7 8832.6 9794.2 10558 9196.8 11622 9607.5 6983.6 10612 9327.2 TRUE FALSE FALSE 9029.568498 9596.050587 10157.18167 10514.31379 9087.134167 9211.466193 9877.060593 9112.867491 9447.89015 9651.319506 0.935578653 0.994273434 1.052413783 1.089417233 0.941543191 0.954425578 1.023389661 0.944209492 0.97892212 1 13.23651048 -2.884884655 12.80416427 0.982732746 0.611949576 0 0.049539179 0 0 0.007069122 0 0.001303513 2.884884655 -0.37078317 S(ph)LSTSGESLYHVLGLDK ddPTM_HeLa_Curcumin_4h_R1 1 SLSTSGESLYHVLGLDK 17 0 Q9H3Z4-2;Q9H3Z4 Q9H3Z4-2 DNAJC5 DnaJ homolog subfamily C member 5 1 0 S(0.494)LS(0.373)T(0.019)S(0.094)GES(0.019)LYHVLGLDK 110.64 0.0005378 30157000 2269.2 2321.7 1857.7 2277.2 4762.2 8395.1 2411.1 737.43 3818.1 2241 TRUE FALSE FALSE 2089.590426 2522.377403 1926.547996 2267.77755 4705.413875 6653.861628 2478.748977 962.2690123 3399.263982 2318.874583 0.901122657 1.087759304 0.83081164 0.977964727 2.029179978 2.86943575 1.068944821 0.414972426 1.465911096 1 11.17920908 -5.789330038 20.67594988 0.954756657 1.648996978 0.150388529 0.615879886 34.96385625 25919.32767 0.089110085 0.161600223 1.62E-06 5.789330038 0.694240321 S(ph)LSVEHLETK ddPTM_HeLa_Curcumin_4h_R1 1 SLSVEHLETK 10 0 J3KN34;P26045-2;P26045 J3KN34 PTPN3 Tyrosine-protein phosphatase non-receptor type;Tyrosine-protein phosphatase non-receptor type 3 1 0 S(0.978)LS(0.022)VEHLETK 99.011 0.0062526 4267800 9414.4 7890.5 7728.6 9028 9276.9 9746.7 6168.8 6139.4 9722.5 6846.2 TRUE FALSE FALSE 8669.240306 8572.519661 8015.028715 8990.644528 9166.279026 7725.124552 6341.879926 8011.274798 8655.966074 7084.10494 1.223759442 1.21010625 1.131410218 1.269129213 1.293921971 1.090487029 0.895226705 1.130880311 1.221885637 1 12.79036987 -4.992218204 24.91557329 1.143267179 1.008004305 0.259666542 0.102053328 239.0747027 765447.5485 0.017034798 0.050973853 1.02E-05 4.992218204 -0.135262874 S(ph)LSVPVDLSR ddPTM_HeLa_Curcumin_4h_R1 1 SLSVPVDLSR 10 0 Q9NYF3;D6RHW3 Q9NYF3 FAM53C Protein FAM53C 1 0 S(0.985)LS(0.015)VPVDLSR 147.28 0.00099567 60378000 5448.1 3614.2 5128.9 4381.8 5174.9 6276.8 5155.2 4884.5 4973.7 4318 TRUE FALSE FALSE 5016.877136 3926.595343 5318.981546 4363.669273 5113.192697 4974.920926 5299.841037 6373.761565 4428.097554 4468.050179 1.12283366 0.878816304 1.190448033 0.976638377 1.144390169 1.113443387 1.186164171 1.426519692 0.991058152 1 12.12542967 -1 0.700713224 1.05036944 48.6473028 0.65881972 0.084808059 120.7103358 0.59642978 0.013261053 9015.397058 0.1 1 47.59693336 S(ph)LTNLSFLTDSEK ddPTM_HeLa_Curcumin_4h_R1 1 SLTNLSFLTDSEK 13 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 S(0.974)LT(0.018)NLS(0.008)FLTDSEK 95.755 0.0092188 91669000 2206.5 1393.1 1654.9 1668.7 1991.1 3048 3548.6 1120 1746 1346.3 TRUE FALSE FALSE 2031.853197 1513.513356 1716.23205 1661.795362 1967.357433 2415.810442 3648.164165 1461.482844 1554.468168 1393.083825 1.458529028 1.086448159 1.231966102 1.192889711 1.412231912 1.734145784 2.618768591 1.049098998 1.115846829 1 10.44406636 -5.325602164 2.884971414 1.213190433 1.896708938 0.349216878 0.372569936 0.20066298 3.266059691 0.051251417 0.132757225 4.72E-06 5.325602164 0.683518505 S(ph)LTNLSFLTDSEKK ddPTM_HeLa_Curcumin_4h_R1 2 SLTNLSFLTDSEKK 14 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 S(0.894)LT(0.105)NLSFLTDSEKK;S(0.985)LT(0.013)NLS(0.003)FLTDSEKK ; 127.88 0.00054437 266090000 6344 4946.7 5408.8 5893.2 5354.6 6965.8 5398.4 3510.4 7154.4 5783.2 TRUE FALSE FALSE 5841.865706 5374.270706 5609.254886 5868.8155 5290.749892 5521.014559 5549.864575 4580.7048 6369.580219 5984.16577 0.976220568 0.898081857 0.937349516 0.980724085 0.884124888 0.92260388 0.927424939 0.765470907 1.064405711 1 12.54693443 -1.158127515 0.245072184 0.997866843 4.50E-14 0.631565778 0.046092909 20.14871438 0.268178457 0.022389458 8.202133523 0.069482028 1.158127515 -0.997866843 AGDGS(ph)SVKEVETYHR ddPTM_HeLa_Curcumin_4h_R1 1 AGDGSSVKEVETYHR 15 1 Q6PL18 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 0 AGDGS(0.5)S(0.5)VKEVETYHR 73.877 0.0089993 10161000 4106.3 3583.7 3914.8 3810 4179.4 5024.7 3206.4 1138.3 4184.9 4115 TRUE FALSE FALSE 3781.282022 3893.459059 4059.885932 3794.23523 4129.563385 3982.52058 3296.362954 1485.36243 3725.82694 4257.995944 0.888042655 0.914387686 0.953473415 0.891084745 0.969837322 0.935303986 0.774158313 0.348840734 0.875018903 1 12.05595886 -4.256529229 2.030472309 0.941802228 0.17077066 0.951849373 0.039217232 0.121377525 0.52699843 0.006456936 0.17330306 5.54E-05 4.256529229 -0.771031568 down S(ph)LTPAVPVESKPDKPSGK ddPTM_HeLa_Curcumin_4h_R1 1 SLTPAVPVESKPDKPSGK 18 2 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;P20810-2;E7EVY3;E9PCH5;P20810-3;F8W7E0;E9PSG1;H0YA91;H0Y944;E7EQK6 P20810-6 CAST Calpastatin 1 0 S(0.736)LT(0.263)PAVPVESKPDKPSGK 83.606 0.0037042 27090000 2005.4 1827.9 1803.3 1871 1988.4 3652.4 2715.1 934.69 2439.8 1922.5 TRUE FALSE FALSE 1846.670474 1985.895531 1870.131884 1863.258298 1964.689629 2894.851069 2791.278399 1219.672678 2172.160044 1989.306732 0.928298509 0.998285231 0.940092272 0.936637004 0.987625285 1.455205988 1.403141282 0.613114438 1.091918109 1 10.95805003 -5.485701556 24.96565037 0.9639411 1.188363205 0.110795031 0.216722955 672.5984865 451670.48 0.028095377 0.062806552 3.27E-06 5.485701556 0.224422104 S(ph)LTPPPSSTESK ddPTM_HeLa_Curcumin_4h_R1 1 SLTPPPSSTESK 12 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 0 S(0.984)LT(0.016)PPPSSTESK 158.34 0.00026545 67482000 7013.4 5398.2 5697.6 5682.5 5665 6652.1 4373.9 2722.1 6674.4 5394.3 TRUE FALSE FALSE 6458.281989 5864.796354 5908.758068 5658.987321 5597.448575 5272.379475 4496.619862 3552.055759 5942.235019 5581.751523 1.157035021 1.050708963 1.058584934 1.013837197 1.002812209 0.944574378 0.805592983 0.63636938 1.064582505 1 12.44650219 -4.096172543 0.730832336 1.072559249 0.263822141 0.929457139 0.037660483 0.880207956 0.281567368 0.009781333 0.616706642 8.01E-05 4.096172543 -0.808737108 S(ph)LVGTPYWMAPELISR ddPTM_HeLa_Curcumin_4h_R1 1 SLVGTPYWMAPELISR 16 0 O96013;M0R1R1;O96013-2;O96013-3;O96013-4 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 0 S(0.983)LVGT(0.016)PY(0.001)WMAPELISR 153.48 0.00038051 62662000 1619 1349.6 1505.4 1355.4 1409.6 2384.7 1910.9 1673.7 1512.2 1324.3 TRUE FALSE FALSE 1490.854442 1466.25341 1561.191448 1349.791714 1392.791441 1890.086339 1964.514711 2184.003425 1346.315443 1370.319326 1.087961333 1.070008561 1.13929025 0.985019833 1.016399181 1.37930357 1.433618189 1.593791595 0.982483 1 10.42029641 -5.093425495 2.53002733 1.04561003 1.514872325 0.91377079 0.061064148 0.058360323 0.721384509 0.008914201 0.029037991 8.06E-06 5.093425495 0.469262294 S(ph)LYASS(ph)PGGVYATR ddPTM_HeLa_Curcumin_4h_R1 4 SLYASSPGGVYATR 14 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 2 0 S(0.996)LY(0.003)AS(0.09)S(0.792)PGGVYAT(0.118)R;S(0.999)LY(0.001)AS(0.071)S(0.929)PGGVYATR;S(0.999)LY(0.001)AS(0.105)S(0.859)PGGVY(0.006)AT(0.031)R;S(1)LYAS(0.005)S(0.935)PGGVYAT(0.06)R ;;; 183.75 0.00018407 130967000 11171.6 8622.42 10652 11882.1 11255.2 19543.1 20688.1 10459.1 10757.8 10574.4 TRUE FALSE FALSE 10287.35607 9367.703564 11046.77249 11832.93502 11120.98909 15489.64076 21268.55241 13648.03144 9577.696255 10941.85961 0.940183519 0.856134505 1.009588213 1.081437291 1.016371027 1.415631466 1.943778586 1.247322843 0.875326187 1 13.41757033 -5.180667529 3.304771266 0.974266693 1.611105159 0.705632173 0.169796001 0.085089287 1.792948563 0.0210692 0.058871286 6.60E-06 5.180667529 0.636838467 S(ph)LYASSPGGVYATR ddPTM_HeLa_Curcumin_4h_R1 1 SLYASSPGGVYATR 14 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 0 S(0.915)LYAS(0.077)S(0.007)PGGVYATR 204.17 4.88E-09 130060000 401.87 405.01 301.05 433.82 482.78 428.47 289.72 313.87 366.95 548.6 TRUE FALSE FALSE 370.0615654 440.0172597 312.2071778 432.0249678 477.0231638 339.6004921 297.8487635 409.5675181 326.6965031 567.6638092 0.651902692 0.775137066 0.549986053 0.761057797 0.840326891 0.598242281 0.524692183 0.721496617 0.575510536 1 9.148892957 -9.378722443 0.600026658 1.062793379 0.668645442 0 0.163795386 0.671487405 0.326036871 0.149296514 0.021978597 4.18E-10 9.378722443 -0.394147937 S(ph)LYESFVSSSDR ddPTM_HeLa_Curcumin_4h_R1 1 SLYESFVSSSDR 12 0 P18615;P18615-3;A0A0A0MT02;A2ABK4 P18615 NELFE Negative elongation factor E 1 0 S(1)LYESFVSSSDR 201.09 8.47E-09 21856000 159.4 213.12 138.64 222.23 236.25 420.93 316.23 358.5 230.28 289.44 TRUE FALSE FALSE 146.7833218 231.5411432 143.7781204 221.3104711 233.432873 333.6243731 325.1025627 467.8049997 205.0188601 299.4980185 0.490097806 0.773097413 0.480063678 0.738938015 0.779413748 1.113945177 1.085491531 1.561963589 0.684541625 1 8.226402648 -4.410642036 0.96442466 0.730553144 1.820933497 0.746606484 0.156550839 0.857809913 0.708769702 0.03313086 0.916308017 3.88E-05 4.410642036 1.090380353 S(ph)LYYYIQQDTK ddPTM_HeLa_Curcumin_4h_R1 2 SLYYYIQQDTK 11 0 P07355;A6NMY6;P07355-2 P07355;P07355-2 ANXA2;ANXA2P2 Annexin A2;Putative annexin A2-like protein 1 0 S(1)LYYYIQQDTK;S(0.985)LY(0.004)YYIQQDT(0.01)K ; 163.99 0.00027789 7098900 2390.2 1256.97 2742.8 1717.49 3225.4 3023.9 2433.4 3302.9 2091.5 1544.26 TRUE FALSE FALSE 2201.013148 1365.616886 2844.450581 1710.383481 3186.939212 2396.709054 2501.674655 4309.939005 1862.067683 1597.92292 1.377421351 0.85462 1.780092485 1.070379215 1.994426121 1.499890279 1.565579055 2.697213333 1.165305072 1 10.6419821 -1 0.362527475 1.145608648 17.48269453 0.608271709 0.327538027 27.36125475 0.338797638 0.085348501 313.1326611 0.1 1 16.33708589 S(ph)MDEFTASTPADLGEAGR ddPTM_HeLa_Curcumin_4h_R1 5 SMDEFTASTPADLGEAGR 18 0 Q7Z5K2;Q7Z5K2-2;Q7Z5K2-3 Q7Z5K2 WAPAL Wings apart-like protein homolog 1 0 S(0.908)MDEFT(0.084)AS(0.006)T(0.001)PADLGEAGR;S(0.983)MDEFT(0.015)AS(0.001)T(0.001)PADLGEAGR;S(0.998)MDEFT(0.001)ASTPADLGEAGR;S(1)MDEFTASTPADLGEAGR;S(1)MDEFTASTPADLGEAGR ;;;; 204.07 4.15E-12 56379300 7065.65 6054.95 6602.17 7302.36 6849.87 7759.74 6801.46 2747.3 6979.22 5706.32 TRUE FALSE FALSE 6506.396347 6578.312898 6846.852228 7272.144769 6768.189774 6150.282454 6992.290662 3584.939123 6213.617027 5904.614195 1.101917269 1.114096989 1.159576562 1.231603713 1.146254361 1.041606149 1.184207881 0.607141975 1.052332434 1 12.52762708 -4.254138665 24.75258817 1.085994761 0.607141714 0.813533775 0.071718315 297.0294416 1007029.955 0.011845386 0.161840809 5.57E-05 4.254138665 -0.478853046 S(ph)MDELNHDFQALALEGR ddPTM_HeLa_Curcumin_4h_R1 6 SMDELNHDFQALALEGR 17 0 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;H0YEH2;E9PR38;Q14671-4 Q5T1Z4 PUM1 Pumilio homolog 1 1 0 S(1)MDELNHDFQALALEGR;S(1)MDELNHDFQALALEGR;S(1)MDELNHDFQALALEGR;S(1)MDELNHDFQALALEGR;S(1)MDELNHDFQALALEGR;S(1)MDELNHDFQALALEGR ;;;;; 94.922 0.0019036 32285800 5025.79 4796.47 3967.63 4864.92 4934.77 5206.35 4392.69 3986.74 5349.63 3926.8 TRUE FALSE FALSE 4627.993418 5211.055494 4114.673858 4844.79025 4875.926091 4126.494322 4515.937059 5202.278673 4762.788973 4063.256008 1.138986421 1.28248269 1.012654347 1.192341866 1.200004647 1.015563458 1.111408449 1.280322644 1.172160692 1 11.98842055 -8.934959934 0.797073051 1.00073253 1.149622762 0 0.102411669 0.618284454 0.732282314 0.053157026 0.017539443 1.16E-09 8.934959934 0.148890232 S(ph)MDLGIADETK ddPTM_HeLa_Curcumin_4h_R1 2 SMDLGIADETK 11 0 Q5VWV2;Q8TEW0-4;Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-8 Q5VWV2 PARD3 Partitioning defective 3 homolog 1 0 S(1)MDLGIADETK;S(1)MDLGIADETK ; 160.86 0.00039106 31994000 12673.2 10657.2 11001.9 10754 13104.9 12014.8 10475.1 5787.4 10567.3 10141.5 TRUE FALSE FALSE 11670.10285 11578.36088 11409.64009 10709.5028 12948.63263 9522.795045 10769.00311 7551.951618 9408.093628 10493.91637 1.1120827 1.103340304 1.087262342 1.020543944 1.233918031 0.907458637 1.026213926 0.719650448 0.89652836 1 13.35726558 -3.734010273 1.242564233 1.065192758 2.80E-17 0.508508615 0.09494303 2.295998057 1.198744071 0.011511666 4.321601849 0.000184497 3.734010273 -1.065192758 S(ph)MDLVADETK ddPTM_HeLa_Curcumin_4h_R1 1 SMDLVADETK 10 0 F5GZI3 F5GZI3 PARD3 1 0 S(1)MDLVADETK 104.59 0.0099346 5038300 1290.4 1824.3 1819.7 1521.2 1756.8 1323.5 1332.2 812.92 1633.1 1224.2 TRUE FALSE FALSE 1188.263478 1981.984363 1887.139683 1514.905677 1735.851307 1048.991181 1369.577947 1060.775566 1453.953016 1266.740859 0.938047802 1.564632852 1.489759859 1.195908119 1.370328663 0.828102428 1.081182419 0.837405345 1.147790415 1 10.3069057 -2.979038789 14.06813986 1.070573967 1.040778262 0 0.258292734 0 0 0.036781489 0 0.001049449 2.979038789 -0.029795704 S(ph)MFSS(ph)NRQKILERTEILNQEWK ddPTM_HeLa_Curcumin_4h_R1 1 SMFSSNRQKILERTEILNQEWK 22 3 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2;E9PDH6;G3XAL2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 2 0 S(0.919)MFS(0.516)S(0.565)NRQKILERTEILNQEWK 50.883 0.0076653 0 863.76 713.36 597.84 736.82 674.46 894.07 560.31 455.21 892.87 607.58 TRUE FALSE FALSE 795.3924846 775.0196597 619.9964763 733.7712341 666.417505 708.6298038 576.0307906 594.0014335 794.9243949 628.6933598 1.265151719 1.232746692 0.986166732 1.167136924 1.060004046 1.127146951 0.916234889 0.944819003 1.264407175 1 9.296212715 -4.763434261 24.89354011 1.123899819 0.930526897 0.421537844 0.096038961 40.34469664 503486.3203 0.015556588 0.050379856 1.72E-05 4.763434261 -0.193372922 S(ph)MGETESGDAFLDLK ddPTM_HeLa_Curcumin_4h_R1 2 SMGETESGDAFLDLK 15 0 B1AKL4;Q9NRA8;Q9NRA8-3;Q9NRA8-2;B1AKL5;B1AKL6 B1AKL4 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 0 S(0.986)MGET(0.014)ESGDAFLDLK;S(1)MGETESGDAFLDLK ; 132.51 0.00078801 11086000 4697.2 4244.1 4466.6 4270.8 4943.6 5858.3 4301.6 1961.34 4165.9 3574.9 TRUE FALSE FALSE 4325.411664 4610.941093 4632.136125 4253.128561 4884.650799 4643.222543 4422.291319 2559.343537 3708.911193 3699.127509 1.169305911 1.246494229 1.252223967 1.14976533 1.320487274 1.255221003 1.195495778 0.69187762 1.002644863 1 11.85296932 -8.963878111 0.892760753 1.005101949 1.173665654 0.121970755 0.165444961 0.882977043 1.335564879 0.089584694 0.031667732 1.09E-09 8.963878111 0.168563705 S(ph)MGYDDLDYGMMSDYGTAR ddPTM_HeLa_Curcumin_4h_R1 6 SMGYDDLDYGMMSDYGTAR 19 0 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12 O60716 CTNND1 Catenin delta-1 1 0 S(0.984)MGY(0.01)DDLDY(0.003)GMMS(0.003)DYGTAR;S(0.921)MGY(0.013)DDLDY(0.041)GMMS(0.024)DY(0.001)GTAR;S(0.999)MGY(0.001)DDLDYGMMSDYGTAR;S(1)MGYDDLDYGMMSDYGTAR;S(1)MGYDDLDYGMMSDYGTAR;S(1)MGYDDLDYGMMSDYGTAR ;;;;; 352.25 8.41E-177 68308500 7408.3 7215.26 7036.89 7783.28 8125.73 7018.76 6291.01 6356.86 7925.43 5997.57 TRUE FALSE FALSE 6821.925238 7838.914924 7297.683334 7751.07485 8028.835977 5562.990058 6467.518809 8295.037351 7056.030157 6205.985111 1.099249372 1.263121774 1.175910545 1.248967684 1.29372466 0.896391138 1.042142173 1.336618958 1.136971815 1 12.59944452 -8.003432001 1.222355333 1.023188173 1.16853456 0.076386354 0.128915677 0.478886126 1.492298608 0.031651001 0.02638346 9.92E-09 8.003432001 0.145346386 S(ph)MPVLGSVSSVTK ddPTM_HeLa_Curcumin_4h_R1 3 SMPVLGSVSSVTK 13 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 0 S(0.995)MPVLGS(0.004)VSSVTK;S(1)MPVLGSVSSVTK;S(1)MPVLGSVSSVTK ;; 165.64 2.81E-09 84171000 4774.19 3519.84 4498.47 4337.32 4266.95 4709.51 4097.01 3168.13 4254.7 4743.3 TRUE FALSE FALSE 4396.307824 3824.079285 4665.187255 4319.373319 4216.069408 3732.704539 4211.961074 4134.078253 3787.970055 4908.129322 0.895719639 0.779131729 0.950502106 0.880044725 0.858997213 0.760514708 0.858160166 0.842292039 0.771774704 1 12.26095755 -9.107426119 0.255812255 1.080091699 0.817746251 0 0.087748356 2.509211233 0.253162376 0.212697918 0.046220532 7.81E-10 9.107426119 -0.262345448 RKPNAGGS(ph)PAPVR ddPTM_HeLa_Curcumin_4h_R1 1 RKPNAGGSPAPVR 13 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 RKPNAGGS(1)PAPVR 48.423 0.020231 100770000 5690.5 3797.4 5319.2 5488.9 4996.1 6172.7 4055.1 836 6168.3 4990.6 TRUE FALSE FALSE 5240.09092 4125.630335 5516.334231 5466.188386 4936.524771 4892.412439 4168.875192 1090.892552 5491.652922 5164.022979 1.014730365 0.798917889 1.068224184 1.058513568 0.955945547 0.947403305 0.807292146 0.211248586 1.063444711 1 12.3342797 -4.255414671 2.070997849 0.994528446 8.96E-16 0.907136642 0.074726517 0.139647474 0.637484485 0.009864256 0.260984403 5.55E-05 4.255414671 -0.994528446 down S(ph)MSDVSAEDVQNLR ddPTM_HeLa_Curcumin_4h_R1 2 SMSDVSAEDVQNLR 14 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424;E9PJ10;E9PK58;E9PLU6 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 S(0.999)MS(0.001)DVSAEDVQNLR;S(1)MSDVSAEDVQNLR ; 222.55 2.24E-14 54046000 1200.93 1344.46 1388.03 1112.85 1455.4 1655.7 1596.72 1178.56 1273.45 1215.34 TRUE FALSE FALSE 1105.875123 1460.669132 1439.471613 1108.245322 1438.045306 1312.289156 1641.519666 1537.897519 1133.755721 1257.572975 0.879372526 1.161498506 1.144642611 0.881257266 1.143508436 1.043509349 1.305307683 1.222909167 0.901542689 1 10.2964264 -4.378576262 0.428440312 0.952488993 1.489976783 0.442648014 0.106633538 2.963960712 0.39188856 0.028015818 0.794925932 4.18E-05 4.378576262 0.53748779 S(ph)NFSNSADDIK ddPTM_HeLa_Curcumin_4h_R1 2 SNFSNSADDIK 11 0 P45973 P45973 CBX5 Chromobox protein homolog 5 1 0 S(1)NFSNSADDIK;S(0.987)NFS(0.013)NSADDIK ; 153.2 0.00047572 187493000 6490.2 5823.2 6087 6824.5 6223.7 11634.4 10324 3751 6707.4 5423.5 TRUE FALSE FALSE 5976.493822 6326.53146 6312.589575 6796.262027 6149.486442 9221.294293 10613.66365 4894.662633 5971.615001 5611.966221 1.064955416 1.127328856 1.124844542 1.211030459 1.095781086 1.643148574 1.891255798 0.872183196 1.064086056 1 12.45429061 -5.302980905 8.453054426 1.06336293 1.510867294 0.312235625 0.245931756 0.232316611 44.86962022 0.032390951 0.072983549 4.98E-06 5.302980905 0.447504363 S(ph)NGDLSPK ddPTM_HeLa_Curcumin_4h_R1 2 SNGDLSPK 8 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 0 S(1)NGDLSPK;S(1)NGDLSPK ; 116.84 0.0092625 37113000 7588.8 7732.4 8098.7 5758.5 8008 7851.2 6493.4 5745.7 6553.2 6960.6 TRUE FALSE FALSE 6988.138472 8400.754201 8398.844946 5734.672853 7912.50983 6222.772619 6675.587328 7497.53748 5834.330355 7202.480332 0.970240549 1.166369614 1.166104531 0.796208055 1.098581248 0.863976343 0.926845617 1.040966047 0.810044608 1 12.8142781 -6.261570044 24.9999738 1.014275495 0.948285294 0.087281739 0.123252404 25.31375386 4843222.769 0.016072198 0.025560354 5.48E-07 6.261570044 -0.065990201 S(ph)NIDISSGLEDEEPKRPLPR ddPTM_HeLa_Curcumin_4h_R1 1 SNIDISSGLEDEEPKRPLPR 20 2 Q9BZ71;Q9BZ71-3 Q9BZ71 PITPNM3 Membrane-associated phosphatidylinositol transfer protein 3 1 0 S(0.998)NIDIS(0.002)S(0.001)GLEDEEPKRPLPR 51.398 0.0098302 12475000 2852.9 2401 2484.8 2508.9 2995.9 2928.9 1437.8 1878.3 2159.9 2310.5 TRUE FALSE FALSE 2627.089955 2608.531741 2576.888874 2498.518837 2960.175849 2321.413124 1478.140798 2450.985023 1922.964374 2390.789703 1.09883774 1.091075362 1.077840042 1.045060063 1.238158189 0.970981731 0.618264666 1.025178007 0.80432184 1 11.22327152 -4.991357169 24.97671294 1.065899923 0.814946713 0.300643268 0.13697277 115.3942143 333468.6683 0.013957318 0.041781268 1.02E-05 4.991357169 -0.25095321 S(ph)NSFNNPLGNR ddPTM_HeLa_Curcumin_4h_R1 4 SNSFNNPLGNR 11 0 O95835;O95835-2 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 0 S(0.5)NS(0.5)FNNPLGNR;S(0.971)NS(0.029)FNNPLGNR;S(0.967)NS(0.033)FNNPLGNR;S(0.885)NS(0.115)FNNPLGNR ;;; 169.09 0.00024663 97277600 7395.24 6150.74 6499.9 7275.3 7542.4 8263.2 6249.6 3518.48 7344.1 6662.91 TRUE FALSE FALSE 6809.898951 6682.382558 6740.792012 7245.196736 7452.461806 6549.319175 6424.946956 4591.248355 6538.470604 6894.445627 0.987736987 0.969241462 0.97771342 1.050874447 1.080937063 0.949941377 0.931901897 0.665934377 0.948367854 1 12.75121884 -4.131759534 1.787470278 0.999582669 0.470855172 0.863955666 0.039210774 0.308173059 0.746238339 0.005245845 0.304436696 7.38E-05 4.131759534 -0.528727498 S(ph)NSLPHPAGGGK ddPTM_HeLa_Curcumin_4h_R1 1 SNSLPHPAGGGK 12 0 G5E9A7;Q09019 G5E9A7 DMWD Dystrophia myotonica WD repeat-containing protein 1 0 S(0.5)NS(0.5)LPHPAGGGK 70.134 0.017463 9831500 9153.3 7974.9 8475.7 8307.2 8054.1 8891.9 6977.3 6145 9491.1 7589.7 TRUE FALSE FALSE 8428.806646 8664.214821 8789.816898 8272.827008 7958.060118 7047.619708 7173.06426 8018.582212 8449.950076 7853.44151 1.073262803 1.103237964 1.119231217 1.053401492 1.013321371 0.897392525 0.91336572 1.021027813 1.075955053 1 12.93910929 -5.46508784 4.700031509 1.048957598 0.941413809 0.586729381 0.045554931 0.147409096 6.703124799 0.007604168 0.017138091 3.43E-06 5.46508784 -0.107543789 S(ph)NSLSTPRPTR ddPTM_HeLa_Curcumin_4h_R1 1 SNSLSTPRPTR 11 1 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 0 S(0.5)NS(0.5)LSTPRPTR 79.886 0.012271 29344000 1754 1248.9 1225.1 1948.9 1524.2 1735.4 1567.8 1177.5 1770.3 1816.7 TRUE FALSE FALSE 1615.169049 1356.849351 1270.503284 1940.835968 1506.02491 1375.458478 1611.788248 1536.514329 1576.102519 1879.83019 0.859210081 0.721793574 0.675860666 1.032452813 0.801149444 0.73169294 0.85741162 0.817368685 0.838428134 1 10.87638663 -8.484774626 0.849710682 0.986768474 0.810346892 0.081906273 0.103890538 0.434140903 0.64818193 0.038146483 0.020206254 3.28E-09 8.484774626 -0.176421582 S(ph)NSNSSSVIT(ph)TEDNK ddPTM_HeLa_Curcumin_4h_R1 1 SNSNSSSVITTEDNK 15 0 H7C4M0;C9JYJ6;Q4L180-6;Q4L180-5;Q4L180-3;Q4L180-7;Q4L180-2;Q4L180 H7C4M0 FILIP1L Filamin A-interacting protein 1-like 2 0 S(0.49)NS(0.17)NS(0.291)S(0.049)S(0.007)VIT(0.767)T(0.226)EDNK 91.926 0.0068432 49453000 0 135.59 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 147.3097954 0 0 0 0 0 0 0 0 0 TEEAAADGGGGMQNEPLT(ph)PGYHGFPAR ddPTM_HeLa_Curcumin_4h_R1 1 TEEAAADGGGGMQNEPLTPGYHGFPAR 27 0 O43251-6;O43251-8 O43251-6 1 0 TEEAAADGGGGMQNEPLT(1)PGYHGFPAR 191.4 7.67E-18 10764000 1765 1264.2 1598.9 1626.4 1557 2440.4 3199.2 7847.9 1808.5 1277.1 TRUE FALSE FALSE 1625.298388 1373.471815 1658.156641 1619.670388 1538.433792 1934.233531 3288.960942 10240.68858 1610.112075 1321.47913 1.22990848 1.03934431 1.254773233 1.225649616 1.164175625 1.463688292 2.488848191 7.749413782 1.218416574 1 10.36793793 -4.164303209 1.947443736 1.136529829 10.95481984 0.995908553 0.12560497 0.050358445 0.161405347 0.02069943 0.961239349 6.85E-05 4.164303209 9.818290016 up S(ph)NSSSEAVLGQEELSAQAK ddPTM_HeLa_Curcumin_4h_R1 1 SNSSSEAVLGQEELSAQAK 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 0 S(0.768)NS(0.164)S(0.052)S(0.016)EAVLGQEELSAQAK 208.64 4.86E-14 7407400 4352.6 3366.9 3891.6 3631.3 3989.7 4616.2 2156.5 1875.2 4794.8 3754.8 TRUE FALSE FALSE 4008.087117 3657.919833 4035.826119 3616.274643 3942.125433 3658.748085 2217.005586 2446.939848 4268.822436 3885.279021 1.031608566 0.941481889 1.038748079 0.930763177 1.01463123 0.941695066 0.570616827 0.629797715 1.098717084 1 11.92380249 -4.81654824 4.653280772 1.003812255 0.597270197 0.91662452 0.048419025 0.026866338 1.184183573 0.005194819 0.017319665 1.53E-05 4.81654824 -0.406542058 S(ph)PAAGSSQSSGWPNDVDAGSPR ddPTM_HeLa_Curcumin_4h_R1 1 SPAAGSSQSSGWPNDVDAGSPR 22 0 C9JWJ8 C9JWJ8 NFIX Nuclear factor 1 1 0 S(1)PAAGSSQSSGWPNDVDAGSPR 136.67 2.59E-05 6378300 197.59 124.8 428.84 276.55 279.71 324.07 278.84 184.06 422.3 425.76 TRUE FALSE FALSE 181.950543 135.5871559 444.7331876 275.4057094 276.3746409 256.854229 286.6634999 240.1790467 375.9747465 440.5551283 0.413002894 0.307764335 1.009483624 0.625133364 0.627332706 0.583024036 0.650687012 0.545173649 0.853411349 1 8.78317875 -9.469424594 1.223536251 0.998691381 0.583708604 0.350264085 0.176908424 0.3550594 0.955706424 0.12231888 0.030519353 3.39E-10 9.469424594 -0.414982776 S(ph)PAGGESATVAAK ddPTM_HeLa_Curcumin_4h_R1 1 SPAGGESATVAAK 13 0 Q147X3 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 0 S(1)PAGGESATVAAK 132.31 0.0014978 13317000 1557.3 1150.6 1374.4 1338 1654.4 1511.9 1458.6 1301.5 1226.2 1029.8 TRUE FALSE FALSE 1434.038062 1250.052737 1425.336473 1332.463711 1634.672361 1198.314897 1499.52439 1698.321359 1091.688928 1065.585473 1.345774785 1.173113531 1.337608769 1.25045221 1.53406029 1.124560091 1.407230511 1.593791771 1.024496819 1 10.0574306 -12.66352849 0.16904594 7.79E-16 1.448922377 0.555021262 0.127787855 25.82742544 0.371457955 8.886707158 0.218941914 2.17E-13 12.66352849 1.448922377 S(ph)PALPPVWDVSASAK ddPTM_HeLa_Curcumin_4h_R1 1 SPALPPVWDVSASAK 15 0 G3V471;P56179;P56179-2;P56179-3 G3V471 DLX6 Homeobox protein DLX-6 1 0 S(1)PALPPVWDVSASAK 148.7 0.00045645 25696000 2217.7 1508.1 2109.7 2235.3 2417.3 2621 1934.2 1305.1 2395 1665.8 TRUE FALSE FALSE 2042.166705 1638.453444 2187.887338 2226.050921 2388.475276 2077.375055 1988.468446 1703.018982 2132.274492 1723.686426 1.184766947 0.950551921 1.269307053 1.291447729 1.385678532 1.205193139 1.153613799 0.988009743 1.237043153 1 10.75128163 -9.188053111 0.452525099 0.957173168 1.199915004 0 0.143345083 2.126638307 0.606346999 0.23817724 0.03935116 6.49E-10 9.188053111 0.242741836 S(ph)PALSDANK ddPTM_HeLa_Curcumin_4h_R1 2 SPALSDANK 9 0 F8WAX8;A0A087WWJ1;P52701-2;P52701;F8W7G9;P52701-3 F8WAX8 MSH6 DNA mismatch repair protein Msh6 1 0 S(1)PALSDANK;S(1)PALSDANK ; 113.44 0.0080376 154791000 8143.4 6061.4 7731 7065.5 8177.3 8322.5 6837.1 3292 7132 6357.7 TRUE FALSE FALSE 7498.841297 6585.320407 8017.517661 7036.264833 8079.791038 6596.319686 7028.930625 4295.715645 6349.637443 6578.629602 1.139878934 1.001017052 1.218721549 1.069563915 1.22818756 1.002689023 1.068449062 0.652980317 0.965191511 1 12.68357137 -4.258024862 5.145875094 1.080712301 0.632734314 0.678368208 0.087606385 0.070898503 6.136446176 0.011467208 0.111979129 5.52E-05 4.258024862 -0.447977987 S(ph)PAPRPPR ddPTM_HeLa_Curcumin_4h_R1 1 SPAPRPPR 8 1 F8VP90;P50281 F8VP90 MMP14 Matrix metalloproteinase-14 1 0 S(1)PAPRPPR 91.265 0.0088155 3475000 1795.2 2085.6 1977.1 1697.9 1531.6 1700.3 1184.4 1171 1603.1 1573.7 TRUE FALSE FALSE 1653.108026 2265.869971 2050.373065 1690.87454 1513.33667 1347.638614 1217.631076 1528.032509 1427.243941 1628.385958 1.015181946 1.391482136 1.259144403 1.038374552 0.929347654 0.827591645 0.747753363 0.938372443 0.876477676 1 10.66922697 -5.585835849 2.814881412 1.062487504 0.83141064 0.391524624 0.143719827 0.245868679 3.934488741 0.022397018 0.050161755 2.60E-06 5.585835849 -0.231076864 S(ph)PAQILISLESEER ddPTM_HeLa_Curcumin_4h_R1 1 SPAQILISLESEER 14 0 A0A075B6G3;H0Y304;A0A087WTU7;A0A5H1ZRP8;A0A5H1ZRP7;A0A087WV90;A0A5H1ZRQ1;A0A5H1ZRP9;A0A5H1ZRQ8;P11532;P11532-11;P11532-4;P11532-2;P11532-3;P11532-14;P11532-8;P11532-12;P11532-17;P11532-6;P11532-5;P11532-7;P11532-15 A0A075B6G3 DMD Dystrophin 1 0 S(1)PAQILISLESEER 99.371 0.005581 12509000 206.74 0 58.247 0 226.01 265.27 53.933 124.86 0 58.187 TRUE FALSE FALSE 190.3763108 0 60.40568506 0 223.3149784 210.2500118 55.44621483 162.9292392 0 60.20899392 3.161924797 0 1.003266807 0 3.708997009 3.492003405 0.920895886 2.70606148 0 1 5.911907105 -9.797304079 1.803458667 0.997187344 2.061788967 0.10418973 1.356721245 0.835957925 4.919183156 1.027574854 0.214579917 1.59E-10 9.797304079 1.064601623 S(ph)PAQILISLESEERGELER ddPTM_HeLa_Curcumin_4h_R1 1 SPAQILISLESEERGELER 19 1 A0A075B6G3;H0Y304;A0A087WTU7;A0A5H1ZRP8;A0A5H1ZRP7;A0A087WV90;A0A5H1ZRQ1;A0A5H1ZRP9;A0A5H1ZRQ8;P11532;P11532-11;P11532-4;P11532-2;P11532-3;P11532-14;P11532-8;P11532-12;P11532-17;P11532-6;P11532-5;P11532-7;P11532-15 A0A075B6G3 DMD Dystrophin 1 0 S(1)PAQILISLESEERGELER 97.69 0.00053195 8202400 399.26 341.14 283.78 418.13 392.2 362.68 352.37 334.07 461.93 450.36 TRUE FALSE FALSE 367.6581497 370.6266215 294.2971364 416.3998888 387.5232712 287.4560798 362.2565538 435.9264051 411.2574347 466.0099765 0.788949096 0.795319071 0.631525399 0.893542864 0.831577199 0.616845334 0.777357937 0.935444362 0.88250779 1 8.864217031 -9.014844036 0.695934471 1.009660497 0.776623194 0.250957914 0.100612063 0.577230889 0.485964107 0.07588519 0.020232227 9.66E-10 9.014844036 -0.233037303 S(ph)PART(ph)PPSEEDSAEAER ddPTM_HeLa_Curcumin_4h_R1 1 SPARTPPSEEDSAEAER 17 1 O43765;K7EMD6 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 2 0 S(1)PART(1)PPSEEDSAEAER 92.563 0.0055881 18088000 2783.1 2687.3 2286.2 2612.3 3067.1 3051 1966 2034 2611.1 2368.8 TRUE FALSE FALSE 2562.814698 2919.578238 2370.928583 2601.490995 3030.526836 2418.188208 2021.160669 2654.157237 2324.668863 2451.115624 1.045570708 1.191122201 0.967285492 1.061349766 1.236386732 0.986566356 0.824588057 1.082836408 0.948412568 1 11.25922283 -5.005660465 24.98116641 1.048729923 0.941678471 0.15304095 0.104099462 327.0082076 1443201.699 0.013460285 0.038625754 9.87E-06 5.005660465 -0.107051453 S(ph)PARTPPSEEDSAEAER ddPTM_HeLa_Curcumin_4h_R1 1 SPARTPPSEEDSAEAER 17 1 O43765;K7EMD6 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 0 S(0.999)PART(0.001)PPSEEDSAEAER 80.382 0.0040341 18238000 1587.4 1478.2 1541.4 1545.2 1458.9 1543.4 1163.2 1444.4 2274.9 1566.5 TRUE FALSE FALSE 1461.755615 1605.969021 1598.52564 1538.806372 1441.50357 1223.281442 1195.836261 1884.790911 2025.349162 1620.935758 0.901797377 0.990766607 0.98617458 0.949332115 0.889303332 0.754676079 0.737744389 1.162779525 1.249493788 1 10.6626112 -5.711397558 4.204931439 0.958307685 0.863744664 0.084275547 0.144545969 0.330810046 12.15966137 0.015767866 0.031846797 1.94E-06 5.711397558 -0.094563021 S(ph)PDEEDYDYESYEK ddPTM_HeLa_Curcumin_4h_R1 2 SPDEEDYDYESYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(1)PDEEDYDYESYEK;S(1)PDEEDYDYESYEK ; 253.06 1.60E-38 35862000 1825.69 1689.53 1698.1 1742.69 2051.1 1806.08 1918.4 2288.23 1792.02 1460.1 TRUE FALSE FALSE 1681.18471 1835.565445 1761.03308 1735.479211 2026.641972 1431.478649 1972.225141 2985.900793 1595.439889 1510.838366 1.112749549 1.214931713 1.165599921 1.148686219 1.341402242 0.947473059 1.305384603 1.976320472 1.055996409 1 10.56113361 -4.298456671 2.928474994 1.095603406 2.089311128 0.844259801 0.108989162 0.099562909 1.268342856 0.016259499 0.221771233 5.03E-05 4.298456671 0.993707721 S(ph)PDEVTLTSIVPTR ddPTM_HeLa_Curcumin_4h_R1 1 SPDEVTLTSIVPTR 14 0 A0A0C4DGG1;Q9UKS6;H0YDM6 A0A0C4DGG1 PACSIN3 Protein kinase C and casein kinase substrate in neurons protein 3 1 0 S(1)PDEVTLTSIVPTR 168 0.00020895 10506000 232.19 158.38 257.18 194.27 198.53 344.76 113.33 153.23 199.68 164.23 TRUE FALSE FALSE 213.8119165 172.0696615 266.711317 193.4661622 196.1626594 273.2528898 116.5097348 199.9491216 177.7756036 169.9369803 1.25818357 1.012549836 1.56947191 1.13845828 1.15432591 1.60796602 0.685605538 1.176607477 1.046126648 1 7.408856024 -9.381780102 0.99584345 0.994578727 1.203901715 0.074741519 0.247840696 1.184306663 2.011515176 0.18324152 0.042413522 4.15E-10 9.381780102 0.209322988 S(ph)PDGPVLSK ddPTM_HeLa_Curcumin_4h_R1 2 SPDGPVLSK 9 0 Q96AY4 Q96AY4 TTC28 Tetratricopeptide repeat protein 28 1 0 S(1)PDGPVLSK;S(1)PDGPVLSK ; 110.54 0.0089755 34478800 9245.2 8115.2 8520.5 8875.6 10916.4 9921.4 7435.3 7330.5 8973.1 7210.9 TRUE FALSE FALSE 8513.432665 8816.641727 8836.277225 8838.875119 10786.22906 7863.589803 7643.914507 9565.535705 7988.77338 7461.478238 1.140984721 1.181621315 1.184252898 1.184601072 1.445588758 1.053891676 1.024450419 1.281989359 1.070668991 1 12.86524576 -8.494227797 0.629595021 1.002210959 1.192826894 0.231350112 0.111442782 0.716996145 0.587466496 0.065353939 0.027972816 3.20E-09 8.494227797 0.190615935 S(ph)PDPGIVPQEAPVGNSLSELSEENFDGK ddPTM_HeLa_Curcumin_4h_R1 4 SPDPGIVPQEAPVGNSLSELSEENFDGK 28 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;X6RGP5;A0A0C4DH09;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 S(1)PDPGIVPQEAPVGNSLSELSEENFDGK;S(0.997)PDPGIVPQEAPVGNS(0.002)LSELSEENFDGK;S(0.999)PDPGIVPQEAPVGNS(0.001)LSELSEENFDGK;S(0.998)PDPGIVPQEAPVGNS(0.002)LSELSEENFDGK ;;; 92.135 1.36E-07 48498700 12458.1 8465.7 12025.5 11371.4 11959.3 10188.6 8095.2 6753.8 8138.8 8455.6 TRUE FALSE FALSE 11472.02824 9197.437386 12471.17561 11324.34816 11816.69316 8075.369511 8322.329525 8813.002529 7245.994002 8749.431471 1.311174135 1.051204003 1.425369826 1.294295315 1.350566971 0.922959342 0.951185177 1.007265736 0.82816741 1 13.09497356 -5.23949695 24.85709976 1.187236771 0.959541564 0.254068617 0.1721584 744.753579 843679.6651 0.022700862 0.05782368 5.76E-06 5.23949695 -0.227695207 S(ph)PDSTANVR ddPTM_HeLa_Curcumin_4h_R1 2 SPDSTANVR 9 0 B7ZM87;O75044;E9PDX4;A0A087WW56;A0A286YEY3;A0A075B7B5;P0DMP2 B7ZM87 SRGAP2;SRGAP2B SLIT-ROBO Rho GTPase-activating protein 2;SLIT-ROBO Rho GTPase-activating protein 2B 1 0 S(0.998)PDS(0.001)T(0.001)ANVR;S(1)PDSTANVR ; 99.752 0.013275 80440000 1925.56 2075.32 1814.97 2099.3 1707.26 2240.61 1805.54 1757.14 2239.67 1904.67 TRUE FALSE FALSE 1773.149894 2254.701413 1882.234385 2090.613653 1686.90204 1775.882229 1856.198593 2292.883897 1993.983804 1970.857141 0.899684638 1.144020724 0.955033394 1.06076367 0.855923042 0.901071007 0.941823004 1.163394266 1.011734318 1 10.94460749 -8.524932353 0.002747866 2.95E-05 1.935453617 0 0.100635014 270256.2658 286.7090448 101710.4233 100226.6926 2.99E-09 8.524932353 1.935424116 S(ph)PEAVGPELEAEEK ddPTM_HeLa_Curcumin_4h_R1 3 SPEAVGPELEAEEK 14 0 Q96N64-3;Q96N64-2;Q96N64 Q96N64-3 PWWP2A PWWP domain-containing protein 2A 1 0 S(1)PEAVGPELEAEEK;S(1)PEAVGPELEAEEK;S(1)PEAVGPELEAEEK ;; 219.52 4.83E-14 250673700 6325.6 5211.3 5303.8 5937.6 5666.2 6963.3 5474 3648.7 6467.9 5836.8 TRUE FALSE FALSE 5824.922085 5661.741551 5500.363494 5913.031784 5598.634266 5519.033087 5627.585707 4761.171833 5758.387552 6039.628366 0.964450415 0.937432108 0.910712243 0.979039011 0.926983239 0.913803425 0.931776819 0.788321987 0.953434086 1 12.56024406 -1.150759292 0.267499197 0.989823272 1.31E-24 0.624465934 0.03345943 18.27070547 0.249074385 0.01479474 8.303345805 0.070670914 1.150759292 -0.989823272 S(ph)PEDQLGK ddPTM_HeLa_Curcumin_4h_R1 2 SPEDQLGK 8 0 Q9UK61-3;Q9UK61;Q9UK61-2 Q9UK61-3 FAM208A Protein FAM208A 1 0 S(1)PEDQLGK;S(1)PEDQLGK ; 117.52 0.0090492 107146000 9325 8239.4 9211.3 9152.8 11494.4 10372.6 7856.2 5203.9 8892.1 7413 TRUE FALSE FALSE 8586.91641 8951.577022 9552.678881 9114.928139 11357.33679 8221.205837 8076.623828 6790.545154 7916.658877 7670.601198 1.11945807 1.1669981 1.245362473 1.188293838 1.480631895 1.071781158 1.052932309 0.885268961 1.032078017 1 12.90512394 -8.39939009 0.875735301 1.014270677 1.162620267 0.121262995 0.144164084 0.77717935 1.244030379 0.055889218 0.032226685 3.99E-09 8.39939009 0.14834959 S(ph)PENSTLEEILGQYQR ddPTM_HeLa_Curcumin_4h_R1 1 SPENSTLEEILGQYQR 16 0 Q86SQ7-2;Q86SQ7-3;Q86SQ7-4;Q86SQ7 Q86SQ7-2 SDCCAG8 Serologically defined colon cancer antigen 8 1 0 S(0.997)PENS(0.003)TLEEILGQYQR 100.35 0.0036516 0 182.2 224.76 160.95 186.47 255.03 308.29 145.22 208.8 278.17 177.12 TRUE FALSE FALSE 167.7786777 244.1872529 166.9149486 185.6984365 251.9889338 244.3471789 149.2944824 272.4621588 247.6554469 183.2749068 0.915448168 1.332355079 0.910735416 1.013223467 1.374923268 1.33322768 0.814593143 1.486631004 1.351278532 1 7.517865462 -6.457052775 0.753741114 0.965255432 1.21869158 0 0.240457388 0.773179822 0.875750824 0.041842237 0.086962452 3.49E-07 6.457052775 0.253436148 S(ph)PEPDGPAPAFLR ddPTM_HeLa_Curcumin_4h_R1 2 SPEPDGPAPAFLR 13 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 0 S(1)PEPDGPAPAFLR;S(1)PEPDGPAPAFLR ; 135.94 0.001255 14310400 1863.31 1639.61 1841.05 1488.97 2355.6 1313.59 1016.13 1236.48 1583.34 1389.45 TRUE FALSE FALSE 1715.827047 1781.330582 1909.280933 1482.809037 2327.511008 1041.136627 1044.639873 1613.47706 1409.651563 1437.733284 1.193425141 1.238985424 1.327979921 1.031351957 1.618875374 0.724151439 0.726588085 1.122236703 0.98046806 1 10.48958035 S(ph)PEPDPYLSYR ddPTM_HeLa_Curcumin_4h_R1 2 SPEPDPYLSYR 11 0 H3BUL5;H3BVF8;H3BQG1;P49761-3;P49761-1;P49761;H3BRT8;H3BQR7;H3BV35;H3BRK0;P49761-2 H3BUL5 CLK3 Dual specificity protein kinase CLK3 1 0 S(1)PEPDPYLSYR;S(1)PEPDPYLSYR ; 101.71 0.010045 6528600 2717.2 2336.74 2545.6 2355.6 2725.4 2808.3 2177.39 1792.83 2518.09 2352.18 TRUE FALSE FALSE 2502.130753 2538.717393 2639.942175 2345.853151 2692.901385 2225.826924 2238.481703 2339.455614 2241.861827 2433.91808 1.02802587 1.043057864 1.084647095 0.963817628 1.106405925 0.914503632 0.919702977 0.961189135 0.921091735 1 11.2490649 -5.229097792 24.98442899 1.022880272 0.930588999 0.382683619 0.051876503 381.374738 294618.1858 0.005419619 0.013816081 5.90E-06 5.229097792 -0.092291273 S(ph)PEPEATLTFPFLDK ddPTM_HeLa_Curcumin_4h_R1 3 SPEPEATLTFPFLDK 15 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 S(1)PEPEATLTFPFLDK;S(1)PEPEATLTFPFLDK;S(1)PEPEATLTFPFLDK ;; 207.66 1.15E-09 1345445000 3636.12 4032.84 4067.03 3612.46 4768.54 3452.54 3599.45 4730.06 3186.81 2962.73 TRUE FALSE FALSE 3348.317265 4381.42072 4217.75771 3597.512598 4711.678275 2736.444286 3700.44088 6172.233519 2837.224916 3065.684647 1.092192332 1.429181806 1.375796338 1.17347771 1.536908984 0.892604622 1.207052031 2.013329559 0.925478398 1 11.58199359 -1 0.198101781 0.990915687 3.795087849 0.344656735 0.260932956 47.73027894 0.545002973 0.25144923 41.74202999 0.1 1 2.804172162 S(ph)PEPEVLSTQEDLFDQSNK ddPTM_HeLa_Curcumin_4h_R1 1 SPEPEVLSTQEDLFDQSNK 19 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 S(1)PEPEVLSTQEDLFDQSNK 155.92 1.48E-05 19865000 3428.8 2896.9 3336.7 2994.3 4091.4 3650.8 3399.6 2408.6 3015.1 2876.6 TRUE FALSE FALSE 3157.406862 3147.295128 3460.361037 2981.91038 4042.612727 2893.582927 3494.983626 3142.971052 2684.351073 2976.561636 1.060756419 1.0573593 1.162536329 1.001796954 1.358148502 0.97212263 1.174168068 1.055906592 0.901829494 1 11.53943105 -7.576927198 0.670540532 1.010616293 1.12411382 0.226402656 0.107758009 0.771704474 0.767363917 0.029568853 0.028043892 2.65E-08 7.576927198 0.113497526 S(ph)PEPGQTWTR ddPTM_HeLa_Curcumin_4h_R1 4 SPEPGQTWTR 10 0 Q09666;E9PKR9;E9PLK4;E9PJZ0;E9PJC6;Q09666-2 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 S(1)PEPGQTWTR;S(1)PEPGQTWTR;S(1)PEPGQTWTR;S(1)PEPGQTWTR ;;; 154.36 0.0006471 788730000 3025.27 2380.77 2509.07 2669.18 2814.28 2016.74 1876.88 2923.32 2676.25 2260.84 TRUE FALSE FALSE 2785.816687 2586.55315 2602.058341 2658.13564 2780.721549 1598.445391 1929.540201 3814.626811 2382.672071 2339.404022 1.190823244 1.105646193 1.112274031 1.136244794 1.18864528 0.683270344 0.824799899 1.630597697 1.01849533 1 11.19192533 S(ph)PESDRPR ddPTM_HeLa_Curcumin_4h_R1 1 SPESDRPR 8 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 0 S(1)PESDRPR 85.161 0.01155 3523600 554.8 889.28 585.96 412.43 530.4 455.43 372.67 261.7 434.42 646.83 TRUE FALSE FALSE 510.8869946 966.1454006 607.6761931 410.7234739 524.0753264 360.9686842 383.1261172 341.4911253 386.7652129 669.3072944 0.763307077 1.44350048 0.907918079 0.613654561 0.783011527 0.539316824 0.572421846 0.510215753 0.577858954 1 9.386524927 -6.272840516 5.781302768 0.937782724 0.607387972 0.375878747 0.215896037 0.132881023 17.50872152 0.030527414 0.04837622 5.34E-07 6.272840516 -0.330394752 S(ph)PESQVIGENTK ddPTM_HeLa_Curcumin_4h_R1 1 SPESQVIGENTK 12 0 O95218-2 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 S(1)PESQVIGENTK 107.93 0.006196 8013100 810.38 685.73 849 898.8 1067.4 891.37 1003.4 1016.9 966.82 639.99 TRUE FALSE FALSE 746.2375679 745.0014456 880.4646869 895.0810038 1054.671952 706.4898142 1031.552703 1326.948129 860.7622649 662.2296049 1.126856248 1.124989641 1.329545947 1.35161732 1.592607676 1.066835141 1.557696448 2.003758393 1.299794299 1 9.371187697 -1 0.264502291 1.018550657 6.761518498 0.573967987 0.188635672 19.53214523 0.246816009 0.081353488 51.50549576 0.1 1 5.742967841 S(ph)PFEGAVTESQSLFSDNFR ddPTM_HeLa_Curcumin_4h_R1 3 SPFEGAVTESQSLFSDNFR 19 0 O95628-5;O95628-3;O95628-2;O95628;O95628-8;O95628-4;O95628-7;O95628-9;O95628-10;O95628-6 O95628-5 CNOT4 CCR4-NOT transcription complex subunit 4 1 0 S(0.999)PFEGAVT(0.001)ESQSLFSDNFR;S(1)PFEGAVTESQSLFSDNFR;S(1)PFEGAVTESQSLFSDNFR ;; 207.43 1.32E-13 28882800 1456.24 1436.35 906.21 1298.58 1585.28 1398.6 802.07 1025.11 1197.83 1222.12 TRUE FALSE FALSE 1340.977067 1560.501694 939.7949398 1293.20682 1566.376571 1108.514595 824.5739255 1337.66132 1066.431046 1264.588579 1.060405803 1.233999515 0.743162603 1.022630476 1.238645198 0.876581216 0.652049164 1.057783806 0.843302765 1 10.30445238 -5.022526729 24.62072742 1.035511801 0.832266153 0.148244995 0.16983993 596.304459 651736.2861 0.020610428 0.053033774 9.49E-06 5.022526729 -0.203245648 S(ph)PGAFDMSGVR ddPTM_HeLa_Curcumin_4h_R1 1 SPGAFDMSGVR 11 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 0 S(1)PGAFDMSGVR 124.12 0.0036623 9567500 651.64 551.67 523.14 579.79 622.25 539.79 508.17 683.14 475.73 464.21 TRUE FALSE FALSE 600.0620064 599.3538966 542.5280286 577.3909826 614.8300752 427.8314693 522.4278825 891.4262412 423.5436092 480.3412629 1.249241014 1.247766833 1.129463718 1.20204327 1.279985965 0.890682318 1.087618164 1.855818581 0.881755622 1 8.907915936 -1 0.025128896 3.18E-13 2.86252601 0.236088323 0.23003245 2676.775419 5.224914295 205.3888425 428.2895892 0.1 1 2.86252601 S(ph)PGALETPSAAGSQGNTASQGK ddPTM_HeLa_Curcumin_4h_R1 4 SPGALETPSAAGSQGNTASQGK 22 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 S(1)PGALETPSAAGSQGNTASQGK;S(1)PGALETPSAAGSQGNTASQGK;S(0.984)PGALET(0.016)PSAAGSQGNTASQGK;S(0.997)PGALET(0.003)PSAAGSQGNTASQGK ;;; 246.1 3.35E-38 185677000 13326 12285.1 12783.1 12127.5 12529.9 12251.4 9216.8 14796.3 12855.8 11551.7 TRUE FALSE FALSE 12271.23304 13346.9693 13256.85293 12077.31962 12380.48913 9710.321538 9475.398602 19307.62376 11445.5509 11953.12072 1.026613328 1.116609597 1.109070447 1.0103905 1.03575371 0.81236706 0.79271337 1.615278906 0.957536628 1 13.54509971 -6.235195315 0.008927925 6.72E-05 2.086177954 0.035952859 0.211372264 14083.14415 49.50495194 5647.898981 5917.692007 5.82E-07 6.235195315 2.086110713 SRSPES(ph)QVIGENTK ddPTM_HeLa_Curcumin_4h_R1 1 SRSPESQVIGENTK 14 1 O95218-2 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 S(0.001)RS(0.308)PES(0.692)QVIGENTK 181.75 0.0010163 4598000 1684.4 1292.4 1422.4 1350.4 1365.4 1966.5 1864.7 3258.3 1094.7 1169 TRUE FALSE FALSE 1551.077963 1404.109297 1475.115395 1344.812403 1349.118497 1558.625733 1917.018463 4251.740671 974.6141488 1209.622663 1.282282492 1.160782895 1.219483927 1.11176191 1.115321776 1.288522265 1.584807 3.514931392 0.805717501 1 10.24034136 -4.162097379 2.010329562 1.146176208 4.648283349 0.965527093 0.135166122 0.107354267 0.370321528 0.01618211 0.750515442 6.88E-05 4.162097379 3.502107141 up S(ph)PGASNFSTLPK ddPTM_HeLa_Curcumin_4h_R1 3 SPGASNFSTLPK 12 0 Q9Y4E8 Q9Y4E8 USP15 Ubiquitin carboxyl-terminal hydrolase 15 1 0 S(1)PGASNFSTLPK;S(0.834)PGAS(0.166)NFSTLPK;S(1)PGASNFSTLPK ;; 190.24 5.76E-06 112698000 6107.4 5218.9 5746.1 5326.9 5983.4 6191.5 4848.7 8184.2 4823.52 4862.96 TRUE FALSE FALSE 5623.992846 5669.998461 5959.055521 5304.858699 5912.051863 4907.313107 4984.741472 10679.5249 4294.391924 5031.947498 1.117657298 1.126800004 1.184244375 1.054235701 1.174903328 0.975231381 0.990618736 2.122344263 0.853425423 1 12.29690115 -4.258842472 24.99976665 1.069189106 2.122344637 0.913969909 0.098309458 38.54886764 371078.4191 0.01075585 0.098387488 5.51E-05 4.258842472 1.053155531 S(ph)PGDTAKDALFASQEK ddPTM_HeLa_Curcumin_4h_R1 1 SPGDTAKDALFASQEK 16 1 Q5QNY5;P40855;E9PS71;B7Z8B3 Q5QNY5 PEX19 Peroxisomal biogenesis factor 19 1 0 S(1)PGDTAKDALFASQEK 79.346 0.0057135 8294500 2437.6 1836.1 1895.7 2345.5 1703.6 2907.4 1735.8 2067.3 2910.8 2123.5 TRUE FALSE FALSE 2244.661388 1994.804302 1965.95631 2335.794942 1683.285683 2304.372467 1784.501876 2697.610253 2591.492522 2197.291467 1.021558324 0.907846925 0.894718038 1.063033729 0.766073008 1.04873318 0.81213708 1.227697961 1.17940317 1 11.10151054 -7.284859241 23.279193 1.010180324 0.951746716 0.069363735 0.136365236 793.4030145 788635.2825 0.018876484 0.0215957 5.19E-08 7.284859241 -0.058433607 S(ph)PGEPGGAAPER ddPTM_HeLa_Curcumin_4h_R1 1 SPGEPGGAAPER 12 0 Q96EB6;Q96EB6-2 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 0 S(1)PGEPGGAAPER 120.63 0.0035009 133910000 443.59 626.59 551.07 369.7 528.46 703 563.91 439.11 418.46 465.17 TRUE FALSE FALSE 408.4793834 680.7496476 571.493139 368.1702794 522.1584596 557.1898756 579.7317969 572.9926176 372.5559849 481.3346229 0.848639105 1.414296033 1.187309435 0.764894653 1.084813838 1.157593593 1.204425714 1.190424687 0.774006205 1 8.910896391 -4.696436496 0.306653462 0.936307256 1.374193052 0.186683916 0.18190063 7.82490465 0.659232988 0.089481379 1.23774768 2.01E-05 4.696436496 0.437885796 S(ph)PGEYINIDFGEPGAR ddPTM_HeLa_Curcumin_4h_R1 2 SPGEYINIDFGEPGAR 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 S(1)PGEYINIDFGEPGAR;S(1)PGEYINIDFGEPGAR ; 146.67 0.00036547 54652000 768.75 798.67 796.61 761.89 817.42 791.83 603.45 500.04 936.11 688.29 TRUE FALSE FALSE 707.9026263 867.703476 826.1330674 758.7375011 807.6728004 627.5955322 620.3811829 652.4998941 833.421075 712.2080263 0.993954856 1.218328696 1.159960344 1.065331298 1.134040576 0.881196938 0.871067385 0.916164758 1.17019332 1 9.476154884 -5.23763568 24.02925152 1.039765201 0.887635409 0.465755338 0.088144486 413.762671 417681.8483 0.013134219 0.033462418 5.79E-06 5.23763568 -0.152129793 S(ph)PGGPGSHVR ddPTM_HeLa_Curcumin_4h_R1 3 SPGGPGSHVR 10 0 O75382-3;O75382-2;O75382;A0A1W2PPI7;O75382-4 O75382-3 TRIM3 Tripartite motif-containing protein 3 1 0 S(1)PGGPGSHVR;S(1)PGGPGSHVR;S(1)PGGPGSHVR ;; 109.16 0.0037652 12344200 3078.49 3634.2 2878.19 2388.8 2503.99 3710.8 2220.75 2263.81 2859.45 2884.32 TRUE FALSE FALSE 2834.824268 3948.324054 2984.858253 2378.915779 2474.131555 2941.138251 2283.058268 2954.035248 2545.775489 2984.549905 0.949833093 1.322921104 1.000103315 0.797076897 0.82897979 0.985454539 0.764958986 0.989775792 0.852984728 1 11.54329766 -6.330243467 9.080861355 1.008961294 0.871085479 0.24662744 0.131232098 0.496086648 62.69753025 0.019014703 0.029068679 4.67E-07 6.330243467 -0.137875815 S(ph)PGKAEAESDALPDDTVIESEALPSDIAAEAR ddPTM_HeLa_Curcumin_4h_R1 4 SPGKAEAESDALPDDTVIESEALPSDIAAEAR 32 1 Q9GZR7-2;Q9GZR7;G3V529;A0A1W2PRR2;F5GYL3 Q9GZR7-2 DDX24 ATP-dependent RNA helicase DDX24 1 0 S(0.975)PGKAEAES(0.025)DALPDDTVIESEALPSDIAAEAR;S(0.985)PGKAEAES(0.015)DALPDDTVIESEALPSDIAAEAR;S(0.485)PGKAEAES(0.127)DALPDDT(0.387)VIESEALPSDIAAEAR;S(0.859)PGKAEAES(0.14)DALPDDT(0.001)VIESEALPSDIAAEAR ;;; 108.69 1.30E-11 307863500 11602.61 9959.27 11111.03 12307.08 11347.74 13397.39 9695.96 5654.17 12049.5 10451.45 TRUE FALSE FALSE 10684.25118 10820.10492 11522.81455 12256.15656 11212.42561 10618.62029 9968.002542 7378.100404 10727.7 10814.63711 0.987943568 1.000505594 1.065483236 1.133293373 1.036782418 0.98187486 0.92171401 0.682232823 0.991961162 1 13.40069764 -4.205933789 1.7727181 1.01274314 0.539997622 0.844834199 0.044412974 0.344088205 0.953855543 0.007295557 0.284243545 6.22E-05 4.205933789 -0.472745518 IQIISTDSAVAS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 2 IQIISTDSAVASPQR 15 0 C9JKS0;P49116;P49116-2;C9JMI6;C9J2Y1 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 0 IQIISTDSAVAS(1)PQR;IQIISTDSAVAS(1)PQR ; 196.45 1.11E-06 62856000 9237.5 7271.7 7718.5 8091.2 8074.4 8791.3 7676.9 2290.99 9313.3 7636.4 TRUE FALSE FALSE 8506.342128 7900.233346 8004.5544 8057.720758 7978.118054 6967.885282 7892.293153 2989.502305 8291.654291 7901.764332 1.076511747 0.999806248 1.013008496 1.019736912 1.00966287 0.881813857 0.998801384 0.378333519 1.04934214 1 12.9479591 -4.255093689 4.718212732 1.019061321 0.337833358 0.936049039 0.049072031 0.036746657 2.225230834 0.00766543 0.082283751 5.56E-05 4.255093689 -0.681227963 down S(ph)PGLLDTTPIR ddPTM_HeLa_Curcumin_4h_R1 1 SPGLLDTTPIR 11 0 Q8IY92-2;Q8IY92 Q8IY92-2 SLX4 Structure-specific endonuclease subunit SLX4 1 0 S(1)PGLLDTTPIR 124.21 0.0036515 11171000 1055.9 622.06 858.83 735.23 990.11 840.46 632.84 189.2 1032.3 964.1 TRUE FALSE FALSE 972.3244008 675.8280946 890.6589953 732.1878131 978.3035849 666.1391221 650.5957872 246.886209 919.0592727 997.6024032 0.974661245 0.677452352 0.892799569 0.733947523 0.9806548 0.667740094 0.652159402 0.247479565 0.921268102 1 9.96232113 -4.287620786 0.518179116 0.969435304 2.01E-48 0.678623652 0.12473456 1.597665336 0.291677222 0.025134203 0.931377633 5.16E-05 4.287620786 -0.969435304 S(ph)PGLVPPS(ph)PEFAPR ddPTM_HeLa_Curcumin_4h_R1 2 SPGLVPPSPEFAPR 14 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 2 0 S(1)PGLVPPS(1)PEFAPR;S(1)PGLVPPS(1)PEFAPR ; 144.15 0.00158 23579300 4058.1 4159.7 3884.5 4258 4762.7 4963.1 4099.8 2793.5 4261.8 3400.3 TRUE FALSE FALSE 3736.897103 4519.245933 4028.462987 4240.381524 4705.907913 3933.697114 4214.829354 3645.22529 3794.291202 3518.460172 1.062083105 1.284438565 1.144950572 1.20518105 1.337490744 1.118016667 1.197918734 1.036028578 1.078395382 1 11.78072847 -7.436190227 5.405312737 1.026728623 1.191259951 0.392887174 0.080912747 0.139412651 6.480584188 0.013419062 0.015173105 3.66E-08 7.436190227 0.164531328 S(ph)PGLYFLTAGDQGTLR ddPTM_HeLa_Curcumin_4h_R1 1 SPGLYFLTAGDQGTLR 16 0 A0A087WYP7;J3KNP2;Q12788 A0A087WYP7 TBL3 Transducin beta-like protein 3 1 0 S(1)PGLYFLTAGDQGTLR 94.339 0.0069106 0 200.62 73.235 62.344 174.4 153.27 316.46 153.56 120.39 163.96 195.49 TRUE FALSE FALSE 184.7407153 79.56510707 64.65452348 173.678379 151.4423554 250.8226288 157.8684803 157.0963568 145.9739982 202.2832629 0.913277315 0.393335098 0.319623693 0.858589962 0.748664784 1.2399574 0.780432736 0.776615695 0.721631617 1 7.660233145 -7.496029682 20.979922 0.961741064 0.735912098 0.04132698 0.249536441 67.40932712 52676.47283 0.04443664 0.048196232 3.19E-08 7.496029682 -0.225828966 S(ph)PGMLEPLGSSR ddPTM_HeLa_Curcumin_4h_R1 1 SPGMLEPLGSSR 12 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(1)PGMLEPLGSSR 128.21 0.0027017 34930000 751.58 625.6 781.23 689.55 683.99 791.03 555.07 267.41 734.17 486.27 TRUE FALSE FALSE 692.0916499 679.6740764 810.183071 686.6968248 675.833866 626.9614613 570.6437703 348.942078 653.6333878 503.1678463 1.375468753 1.350789963 1.610164634 1.364747032 1.343157896 1.246028469 1.134102218 0.693490414 1.29903648 1 8.974895923 -4.250921189 2.415511021 1.25293899 0.555052502 0.576642866 0.154636786 0.458607636 3.147005889 0.029199213 0.670353984 5.61E-05 4.250921189 -0.697886488 S(ph)PGNTSQPPAFFSK ddPTM_HeLa_Curcumin_4h_R1 2 SPGNTSQPPAFFSK 14 0 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;Q9Y618-2;H7C184 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 S(1)PGNTSQPPAFFSK;S(1)PGNTSQPPAFFSK ; 216.01 7.81E-14 443020000 12545.2 10050.4 11094.1 10569.7 12395 11563.8 9600.7 4223.6 10385.1 9308.5 TRUE FALSE FALSE 11552.23418 10919.11179 11505.25711 10525.96538 12247.19772 9165.337529 9870.069803 5511.356197 9245.880512 9631.969682 1.199363636 1.133632284 1.194486433 1.09281546 1.271515393 0.951553818 1.024719775 0.572194097 0.959915865 1 13.23361514 -3.97445569 1.42775397 1.113670609 1.33E-10 0.71716193 0.099400215 0.987870659 1.055310551 0.014525469 1.90669819 0.000106058 3.97445569 -1.113670609 S(ph)PGNVNNTIVVPLLEDGR ddPTM_HeLa_Curcumin_4h_R1 1 SPGNVNNTIVVPLLEDGR 18 0 Q9Y4X4;Q9Y4X4-3;Q9Y4X4-2 Q9Y4X4 KLF12 Krueppel-like factor 12 1 0 S(1)PGNVNNTIVVPLLEDGR 267.69 1.01E-53 3298600 174.7 168.4 147.08 208.21 208.71 215.46 196.63 172.55 183.08 169.18 TRUE FALSE FALSE 160.8723107 182.9557456 152.5309142 207.3484822 206.2212696 170.7711673 202.1469086 225.1597007 162.996582 175.0589924 0.918960565 1.045109098 0.871311505 1.184449192 1.178010148 0.975506399 1.154735931 1.286193286 0.931095169 1 7.451697362 -6.251099332 24.9666462 0.962174115 1.14694097 0.590241735 0.084031119 409.0650543 987710.5921 0.012574466 0.020702211 5.61E-07 6.251099332 0.184766854 S(ph)PGPIVSR ddPTM_HeLa_Curcumin_4h_R1 1 SPGPIVSR 8 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 S(1)PGPIVSR 94.409 0.018325 9167900 171.46 169.9 191.94 282.26 259.81 188.89 204.04 305.68 153.69 251.5 TRUE FALSE FALSE 157.8887601 184.5853989 199.0534652 281.0920829 256.7119354 149.7120848 209.7648133 398.8804248 136.8305915 260.2396063 0.606705345 0.709290187 0.764885361 1.08012799 0.986444527 0.575285549 0.806044922 1.532742961 0.52578696 1 8.023696735 -6.282785879 23.75293045 0.796648017 0.961650729 0.186520245 0.259562208 874.6966101 973300.9497 0.040998423 0.062672794 5.21E-07 6.282785879 0.165002712 T(ph)SFSVGS(ph)DDELGPIR ddPTM_HeLa_Curcumin_4h_R1 2 TSFSVGSDDELGPIR 15 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 2 0 T(0.99)S(0.01)FS(0.025)VGS(0.975)DDELGPIR;T(0.96)S(0.041)FS(0.009)VGS(0.991)DDELGPIR ; 185.86 9.24E-05 15296800 5530.9 5110.6 4340.5 4836.3 5090.9 6525.4 4826.4 1731.08 6278.9 5393.9 TRUE FALSE FALSE 5093.123429 5552.337492 4501.362748 4816.288672 5030.194342 5171.958484 4961.815794 2258.878323 5590.120379 5581.337624 0.912527385 0.994804089 0.8065025 0.862927312 0.901252474 0.926652145 0.889001191 0.404719885 1.001573593 1 12.4463952 -4.255080565 3.705842747 0.936436482 0.344030761 0.87020792 0.05992904 0.074694691 1.887475549 0.009105952 0.122101792 5.56E-05 4.255080565 -0.59240572 down S(ph)PGS(ph)TPT(ph)TPTSSQAPQK ddPTM_HeLa_Curcumin_4h_R1 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 3 0 S(0.997)PGS(0.808)T(0.209)PT(0.794)T(0.145)PT(0.027)S(0.017)S(0.003)QAPQK 98.062 0.0014419 0 492.52 358.33 533.21 579.3 481.12 568.18 733.01 730.8 441.22 471.03 TRUE FALSE FALSE 453.5365223 389.3024485 552.9712317 576.9030101 475.3829582 450.3330633 753.5762878 953.6175558 392.8192699 487.3982574 0.930525531 0.798735823 1.134536743 1.183637818 0.975348087 0.923952961 1.546120193 1.956546913 0.805951322 1 8.928957283 -4.568332129 2.816043607 0.979266107 1.933682367 0.878049309 0.120812043 0.061945487 0.910462477 0.015833381 0.097884428 2.70E-05 4.568332129 0.95441626 S(ph)PGSNSKVPEIEVTVEGPNNNNPQTSAVR ddPTM_HeLa_Curcumin_4h_R1 1 SPGSNSKVPEIEVTVEGPNNNNPQTSAVR 29 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 0 S(0.707)PGS(0.057)NS(0.058)KVPEIEVT(0.177)VEGPNNNNPQTSAVR 57.985 0.0012708 24862000 1452 852.44 651.47 939.28 627.88 1138.8 903.52 798.42 1553 1494.3 TRUE FALSE FALSE 1337.072668 926.1211152 675.6140513 935.3935082 620.3929411 902.6000431 928.8703395 1041.854583 1382.639785 1546.226814 0.864732558 0.598955539 0.436943691 0.604952326 0.401230231 0.583743624 0.600733561 0.673804498 0.894202437 1 10.59453625 -7.333373404 2.28695603 0.946799012 0.545979537 0.812782112 0.080368624 0.085622469 0.846837329 0.015466951 0.017853916 4.64E-08 7.333373404 -0.400819475 S(ph)PGSPPGPELPIETALDDRER ddPTM_HeLa_Curcumin_4h_R1 2 SPGSPPGPELPIETALDDRER 21 1 F5GZI3;B1AP52;Q5VWV2;Q8TEW0-4;Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-3;Q8TEW0-7;Q8TEW0-6;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 F5GZI3;Q5VWV2 PARD3 Partitioning defective 3 homolog 1 0 S(0.851)PGS(0.149)PPGPELPIETALDDRER;S(0.795)PGS(0.203)PPGPELPIET(0.002)ALDDRER ; 106.63 2.59E-05 29312000 3331.2 3011.3 3340.4 2985.5 3366.6 4032.2 2738.8 2028.49 3664 2838.6 TRUE FALSE FALSE 3067.532005 3271.583354 3464.198163 2973.146792 3326.455494 3195.876268 2815.643357 2646.967263 3262.068367 2937.241139 1.044358246 1.113828657 1.179405435 1.012224278 1.132510181 1.088053761 0.958601362 0.901174653 1.110589227 1 11.520246 -4.587791772 4.504735839 1.050094975 0.91257548 0.4490376 0.06077653 0.155070901 6.057050822 0.009256839 0.039678243 2.58E-05 4.587791772 -0.137519496 S(ph)PGSQAPDEGAGGALR ddPTM_HeLa_Curcumin_4h_R1 2 SPGSQAPDEGAGGALR 16 0 P10075 P10075 GLI4 Zinc finger protein GLI4 1 0 S(0.999)PGS(0.001)QAPDEGAGGALR;S(0.985)PGS(0.015)QAPDEGAGGALR ; 152.94 0.00033116 34145000 794.85 826.81 776.73 972.45 966.92 1397.14 896.36 711.22 1223.89 965.32 TRUE FALSE FALSE 731.9367838 898.2757722 805.5162971 968.4262596 955.3901105 1107.357415 921.5094492 928.0677039 1089.632329 998.8647981 0.732768624 0.899296655 0.80643176 0.969526868 0.956475904 1.108615918 0.922556737 0.929122445 1.090870687 1 9.964145604 -6.146377432 6.6079859 0.868418722 0.981666687 0.048236888 0.1063237 0.316771303 16.34665406 0.016609697 0.027687471 7.14E-07 6.146377432 0.113247965 SQSSEGVSS(ph)LSSS(ph)PSNSLETQSQSLSR ddPTM_HeLa_Curcumin_4h_R1 1 SQSSEGVSSLSSSPSNSLETQSQSLSR 27 0 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 2 0 S(0.002)QS(0.002)S(0.007)EGVS(0.293)S(0.669)LS(0.029)S(0.292)S(0.706)PS(0.001)NSLETQSQSLSR 129.52 4.63E-08 17826000 3137.2 2496.8 2698.4 2997.1 2729.2 3426.1 2180.5 633.11 3210.9 3146.4 TRUE FALSE FALSE 2888.88731 2712.612266 2798.405078 2984.698794 2696.656072 2715.48824 2241.678961 826.1423245 2858.672303 3255.737166 0.88732203 0.833179132 0.859530403 0.916750537 0.828278186 0.834062488 0.68853192 0.253749699 0.878041487 1 11.66876852 -4.254612578 1.314149235 0.921850913 8.10E-28 0.92136623 0.055002033 0.311478535 0.450454518 0.010160164 0.385252076 5.56E-05 4.254612578 -0.921850913 down LAS(ph)TSDIEEKENR ddPTM_HeLa_Curcumin_4h_R1 1 LASTSDIEEKENR 13 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 LAS(0.8)T(0.15)S(0.051)DIEEKENR 79.804 0.009745 35512000 2422.9 2138.2 2589.6 2382.1 2728.9 4113.1 5843.3 11800 3208.8 2882.1 TRUE FALSE FALSE 2231.124908 2323.01648 2685.572854 2372.243501 2696.35965 3259.996696 6007.247272 15397.76568 2856.802668 2982.25276 0.748134074 0.778946879 0.900518189 0.795453535 0.904135184 1.093132259 2.014332035 5.163132342 0.957934453 1 11.54218682 -4.161731466 1.7073071 0.867412496 7.459145531 0.995569964 0.085875912 0.069004349 0.159640721 0.015995267 0.799079655 6.89E-05 4.161731466 6.591733035 up ALLETAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 ALLETASPR 9 0 Q96BT3;H3BMP6;H3BQS6;H3BN05;H3BTS2;H3BQJ0;I3L4F8;H3BUW2;H3BTR4;Q96BT3-3;Q96BT3-2 Q96BT3 CENPT Centromere protein T 1 0 ALLETAS(1)PR;ALLETAS(1)PR ; 147.3 0.0018842 79724000 6991.5 5306.2 5834.7 5996.2 6269.7 7708.2 5657.1 1503.21 6734.9 5968.8 TRUE FALSE FALSE 6438.115398 5764.844284 6050.939115 5971.389313 6194.937922 6109.432431 5815.823001 1961.531809 5996.09832 6176.215356 1.042404616 0.933394312 0.979716342 0.966836318 1.003031398 0.98918708 0.94164835 0.317594465 0.970836989 1 12.59250734 -4.254552369 3.661756636 1.004048452 0.236811273 0.975682585 0.031368537 0.032480796 0.787759249 0.004999191 0.068247438 5.56E-05 4.254552369 -0.767237178 down S(ph)PGVAAAVAEDGGLKK ddPTM_HeLa_Curcumin_4h_R1 4 SPGVAAAVAEDGGLKK 16 1 E9PLH8;E9PM78;H0YD80;E9PLS2;E9PQV9;E9PM04;Q9BTE7 E9PLH8 DCUN1D5 DCN1-like protein;DCN1-like protein 5 1 0 S(1)PGVAAAVAEDGGLKK;S(1)PGVAAAVAEDGGLKK;S(1)PGVAAAVAEDGGLKK;S(1)PGVAAAVAEDGGLKK ;;; 167.92 0.00025901 95202000 11412.2 9328.24 10941 9554.64 9334.07 10615.8 7947.81 5706.46 10356.51 9494.58 TRUE FALSE FALSE 10508.91233 10134.5315 11346.48308 9515.105431 9222.767312 8413.963415 8170.804158 7446.333385 9220.426764 9824.515948 1.069662097 1.0315553 1.154915229 0.968506284 0.938750302 0.856425239 0.831674985 0.757933869 0.938512066 1 13.26217061 -5.355867496 1.285014374 1.041451295 0.787182144 0.750543683 0.055947593 0.151793628 0.462197718 0.007664756 0.029496305 4.41E-06 5.355867496 -0.254269151 S(ph)PGYESESSR ddPTM_HeLa_Curcumin_4h_R1 2 SPGYESESSR 10 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 0 S(1)PGYESESSR;S(1)PGYESESSR ; 132.03 0.0026329 52484000 2265 1542.43 1755.32 1735.05 1534.46 2255.1 1900.55 811.66 1995.04 1665.85 TRUE FALSE FALSE 2085.72286 1675.750776 1820.373703 1727.870823 1516.162567 1787.36684 1953.874318 1059.131398 1776.189103 1723.738164 1.209999816 0.97216086 1.056061612 1.002397498 0.879578232 1.036913191 1.133509926 0.614438678 1.0304286 1 10.75132493 -6.3276119 1.185298428 1.094510573 0.935921188 0.153626163 0.139789331 0.588489163 1.634847447 0.024845713 0.047597026 4.70E-07 6.3276119 -0.158589384 S(ph)PHQLLSPSSFSPSATPSQK ddPTM_HeLa_Curcumin_4h_R1 2 SPHQLLSPSSFSPSATPSQK 20 0 E9PIQ6;A0A3B3ITS5;Q14181 E9PIQ6 POLA2 DNA polymerase alpha subunit B 1 0 S(0.786)PHQLLS(0.213)PSSFSPSATPSQK;S(0.969)PHQLLS(0.03)PS(0.001)S(0.001)FSPSATPSQK ; 81.525 0.0011785 70712000 3436 2641.1 2466.9 2465.8 3644.5 4419 2335.3 2071.26 3539.5 2827.1 TRUE FALSE FALSE 3164.036974 2869.384915 2558.325484 2455.597173 3601.041718 3502.449588 2400.822233 2702.777639 3151.225705 2925.341515 1.081595759 0.980871772 0.874539082 0.839422392 1.230981648 1.197278872 0.820698103 0.923918669 1.077216349 1 11.51438934 -4.730107019 24.99981623 1.03149685 0.872308283 0.229415777 0.119284821 237.9942072 189890.2008 0.016917285 0.063285934 1.86E-05 4.730107019 -0.159188567 S(ph)PIALPVKQEPPQIDAVK ddPTM_HeLa_Curcumin_4h_R1 1 SPIALPVKQEPPQIDAVK 18 1 Q8TF01;Q8TF01-2 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 0 S(1)PIALPVKQEPPQIDAVK 95.622 0.00088749 39556000 840.23 637.45 1003.5 650.58 575.15 786.33 538.87 508.22 698.76 822.61 TRUE FALSE FALSE 773.7249089 692.5483376 1040.690593 647.8880723 568.2917119 623.2362942 553.9892419 663.1739384 622.1077762 851.1956363 0.908985991 0.813618289 1.222622096 0.761150604 0.667639362 0.73218925 0.650836562 0.779108715 0.730863446 1 9.733346945 -6.022758311 24.80843029 0.962344792 0.706321061 0.423766465 0.125799263 337.1806159 367554.4887 0.014547408 0.024244826 9.49E-07 6.022758311 -0.25602373 S(ph)PIINESR ddPTM_HeLa_Curcumin_4h_R1 1 SPIINESR 8 0 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 0 S(1)PIINESR 102.05 0.013854 24176000 614.31 563.65 536.38 447.88 637.74 614.01 569.24 639.28 520.56 396.35 TRUE FALSE FALSE 565.6867153 612.3693944 556.2587146 446.0267912 630.135367 486.6574047 585.2113424 834.1935291 463.4558704 410.123133 1.379309456 1.493135464 1.356321236 1.087543607 1.536454095 1.186612911 1.4269162 2.034007502 1.130040793 1 8.679913311 -1.000000016 0.041582184 4.61E-08 3.688455724 0.410278746 0.21648307 483.3503436 1.544468782 37.07187493 124.2582013 0.099999996 1.000000016 3.688455678 S(ph)PILEEK ddPTM_HeLa_Curcumin_4h_R1 2 SPILEEK 7 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;A0A0A0MR81;F5GXF5;Q12830-2 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 0 S(1)PILEEK;S(1)PILEEK ; 106.88 0.016886 17960200 5421.1 4791.2 5667.3 5808.1 6549.2 6322.3 4882.3 3671.1 5868.3 5651.9 TRUE FALSE FALSE 4992.014215 5205.329979 5877.335123 5784.067621 6471.105067 5010.983713 5019.284198 4790.40149 5224.562172 5848.303104 0.85358336 0.890058173 1.004964178 0.98901639 1.106492764 0.85682695 0.858246248 0.819109647 0.893346682 1 12.51380237 -5.033240554 24.99563329 0.947841733 0.843392488 0.362652198 0.069894594 644.4131949 484574.1708 0.011615737 0.029637479 9.26E-06 5.033240554 -0.104449245 S(ph)PILEEKDIPPLEFPK ddPTM_HeLa_Curcumin_4h_R1 2 SPILEEKDIPPLEFPK 16 1 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;A0A0A0MR81;F5GXF5;Q12830-2 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 0 S(1)PILEEKDIPPLEFPK;S(1)PILEEKDIPPLEFPK ; 115.2 0.00054044 215150000 10999.4 7693.2 9805.5 11423.5 8049 11205.7 8504.6 5345.5 11407.6 10060.2 TRUE FALSE FALSE 10128.78588 8358.165928 10168.90046 11376.23258 7953.020932 8881.511506 8743.216187 6975.318342 10156.21482 10409.7912 0.973005672 0.802913888 0.976859214 1.092839651 0.76399428 0.853188247 0.839903128 0.670072839 0.975640589 1 13.34565351 -2.893058527 0.363420939 0.989191314 8.71E-16 0.498503697 0.086868512 8.656784994 0.370248776 0.024477812 4.641308512 0.001279209 2.893058527 -0.989191314 S(ph)PISDNSGCDAPGNSNPSLSVPSSAESEK ddPTM_HeLa_Curcumin_4h_R1 1 SPISDNSGCDAPGNSNPSLSVPSSAESEK 29 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 0 S(0.961)PIS(0.039)DNSGCDAPGNSNPSLSVPSSAESEK 115.19 5.22E-13 33569000 3122.6 2613.9 2848.2 2726.1 3049.1 2902.7 2521.8 2056.9 2981.8 2532 TRUE FALSE FALSE 2875.442915 2839.833869 2953.756798 2714.820121 3012.741474 2300.6473 2592.554921 2684.039341 2654.704 2619.986812 1.09750282 1.083911513 1.127393766 1.036196102 1.149907114 0.878114077 0.98952976 1.024447653 1.013250902 1 11.35534383 -5.261438372 25 1.06143803 0.966580428 0.423967914 0.056936845 0.086948001 1975502.308 0.008674913 0.020650435 5.48E-06 5.261438372 -0.094857603 S(ph)PISPELHSAPLTPVAR ddPTM_HeLa_Curcumin_4h_R1 1 SPISPELHSAPLTPVAR 17 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;A0A0G2JQF5;A0A0G2JQF4;Q7Z3B3-4;Q7Z3B3-2 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 0 S(0.998)PISPELHS(0.001)APLTPVAR 167.92 8.68E-05 5391600 139.62 134.89 147.49 200.21 332.42 207.33 182.07 0 142.87 114.35 TRUE FALSE FALSE 128.5689297 146.5492905 152.9561091 199.3815841 328.4561086 164.3274209 187.1783942 0 127.1975184 118.323654 1.086586877 1.238546018 1.292692577 1.685052628 2.775912487 1.38879603 1.581918643 0 1.074996538 1 6.8865947 -6.766893735 2.050302412 1.044133538 1.546617644 0.072318701 0.631029085 0.532746585 4.590434199 0.105348452 0.15043499 1.71E-07 6.766893735 0.502484106 S(ph)SLSGDEEDELFK ddPTM_HeLa_Curcumin_4h_R1 2 SSLSGDEEDELFK 13 0 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 0 S(0.891)S(0.109)LSGDEEDELFK;S(0.994)S(0.006)LSGDEEDELFK ; 360.74 1.31E-184 67742000 8637.9 7713.7 7174.3 7213.4 8475.7 10322.8 9630.4 13376.5 8293.2 7380.1 TRUE FALSE FALSE 7954.2011 8380.437856 7440.185869 7183.552862 8374.632813 8181.734918 9900.603105 17454.93327 7383.456709 7636.557926 1.041595072 1.09741037 0.974285266 0.940679418 1.096650205 1.071390409 1.296474564 2.285706917 0.966856636 1 12.89870679 -4.159976298 1.889735553 1.022445412 2.923635563 0.982099315 0.051091115 0.092825792 0.273614312 0.006964568 0.336448649 6.92E-05 4.159976298 1.901190151 up S(ph)PKPAAPAAPPFSSSSGVLGTGLCELDR ddPTM_HeLa_Curcumin_4h_R1 2 SPKPAAPAAPPFSSSSGVLGTGLCELDR 28 1 O43294;H3BQC4;O43294-2;H3BSN4;H3BS04;H3BN49 O43294 TGFB1I1 Transforming growth factor beta-1-induced transcript 1 protein 1 0 S(0.956)PKPAAPAAPPFS(0.018)S(0.024)S(0.002)S(0.001)GVLGTGLCELDR;S(0.995)PKPAAPAAPPFS(0.005)SSSGVLGTGLCELDR ; 92.887 1.17E-07 738240000 2594.6 2208.98 2521.1 2417.7 2538.07 3023.3 2522.23 1972.73 2590.27 2704.9 TRUE FALSE FALSE 2389.234672 2399.914388 2614.534184 2407.696198 2507.805173 2396.2335 2592.996986 2574.206296 2306.123862 2798.895074 0.853634956 0.857450646 0.934130832 0.860230961 0.89599828 0.856135524 0.926435939 0.919722329 0.823940806 1 11.45064169 -9.374786058 1.061147726 1.000996049 0.885589102 0 0.061485537 0.248333325 0.493496048 0.02163562 0.005392405 4.22E-10 9.374786058 -0.115406947 S(ph)PLAQMEEER ddPTM_HeLa_Curcumin_4h_R1 1 SPLAQMEEER 10 0 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;A0A0U1RRM2 G3V1Q4 7-Sep Septin-7 1 0 S(1)PLAQMEEER 126.5 0.0034409 12132000 438.22 375.75 361.1 400.1 372.55 410.48 258.78 176.7 306.39 311.62 TRUE FALSE FALSE 403.5344246 408.2281557 374.4826837 398.4444922 368.1075846 325.3418209 266.0406703 230.5750166 272.7797835 322.4487718 1.251468326 1.266024843 1.161371096 1.235683082 1.141600207 1.00897212 0.82506337 0.715074879 0.845963165 1 8.332926164 -4.797151861 1.861266118 1.14642522 0.717029985 0.583063638 0.120951671 0.180203502 1.131541686 0.015972472 0.093349514 1.60E-05 4.797151861 -0.429395234 S(ph)PLAQMEEERR ddPTM_HeLa_Curcumin_4h_R1 5 SPLAQMEEERR 11 1 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;A0A0U1RRM2 G3V1Q4 7-Sep Septin-7 1 0 S(1)PLAQMEEERR;S(1)PLAQMEEERR;S(1)PLAQMEEERR;S(1)PLAQMEEERR;S(1)PLAQMEEERR ;;;; 122.1 0.0018402 288720700 7455.36 6418.75 6471.37 7222.12 7458.26 7604.1 6297 5282.1 7232.75 6677.72 TRUE FALSE FALSE 6865.260389 6973.558149 6711.204665 7192.236781 7369.325121 6026.923944 6473.676872 6892.587974 6439.33542 6909.770273 0.993558413 1.009231548 0.971263067 1.040879291 1.066507978 0.872232174 0.936887424 0.997513333 0.93191744 1 12.75442203 -5.261536981 25 1.003251365 0.935678625 0.321189404 0.044181191 6.63564931 1699929.488 0.005273436 0.012531949 5.48E-06 5.261536981 -0.06757274 S(ph)PLELEPEAK ddPTM_HeLa_Curcumin_4h_R1 3 SPLELEPEAK 10 0 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 0 S(1)PLELEPEAK;S(1)PLELEPEAK;S(1)PLELEPEAK ;; 164.48 0.00058375 89972000 11274.8 8297.9 9695 10232.2 10463.6 11410.2 11084.6 10462.3 10517.1 9305.6 TRUE FALSE FALSE 10382.38768 9015.133501 10054.30523 10189.86187 10338.8284 9043.595901 11395.60404 13652.20711 9363.400442 9628.968907 1.078245011 0.93625118 1.044172572 1.058250573 1.073721237 0.939207093 1.183470853 1.417826482 0.972419844 1 13.2331656 -4.410856251 2.970833366 1.030073607 1.42942346 0.844488529 0.053515698 0.081842718 1.169162913 0.007123332 0.063586969 3.88E-05 4.410856251 0.399349853 S(ph)PLELEPEAKK ddPTM_HeLa_Curcumin_4h_R1 1 SPLELEPEAKK 11 1 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 0 S(1)PLELEPEAKK 70.412 0.018548 7214600 2434.9 2468.7 2158.7 2340.9 2515.1 2929.7 2074 1582.7 2890.5 2413.6 TRUE FALSE FALSE 2242.175096 2682.083428 2238.703321 2331.213976 2485.109075 2322.047195 2132.190858 2065.257944 2573.419382 2497.47242 0.89777772 1.073919138 0.896387605 0.933429317 0.995049657 0.929758894 0.853739501 0.82693924 1.03040953 1 11.28625303 -4.772683588 2.991618168 0.957126777 0.83221701 0.467168034 0.054943313 0.180721643 3.225081074 0.007619671 0.032264496 1.69E-05 4.772683588 -0.124909767 S(ph)PLGEAPPGTPPCR ddPTM_HeLa_Curcumin_4h_R1 1 SPLGEAPPGTPPCR 14 0 M0QXZ5;Q96B54 M0QXZ5 ZNF428 Zinc finger protein 428 1 0 S(1)PLGEAPPGTPPCR 120.29 0.0022389 0 1683.5 1068 1513.5 1339.9 1340.6 2136.9 1546.7 1280.6 1188.4 1318.6 TRUE FALSE FALSE 1550.249199 1160.313161 1569.591641 1334.355849 1324.614221 1693.682852 1590.096239 1671.049045 1058.035493 1364.421252 1.136195436 0.850406837 1.150371734 0.977964721 0.97082497 1.241319607 1.165399789 1.22473103 0.77544636 1 10.41407342 -5.253208692 24.96316028 1.043826267 1.205975115 0.365292321 0.120065778 466.0373022 1413458.364 0.012495474 0.031270012 5.58E-06 5.253208692 0.162148847 S(ph)PLGSVR ddPTM_HeLa_Curcumin_4h_R1 1 SPLGSVR 7 0 Q92620;J3KSA8;H3BMS7;Q92620-2 Q92620 DHX38 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 1 0 S(1)PLGSVR 109.48 0.016161 43205000 1060.6 894.29 1002 856.53 1034.8 1403.3 1208.5 660.06 1088.2 626.13 TRUE FALSE FALSE 976.6523909 971.5884427 1039.135001 852.9859058 1022.460686 1112.239762 1242.407257 861.3092555 968.8271825 647.8879709 1.507440228 1.499624142 1.603880683 1.316563888 1.578144265 1.716716179 1.917626678 1.329410784 1.495362202 1 9.339600562 -10.57913766 0.241558159 0.291610099 1.672474135 0.065234855 0.226943841 5.250829701 0.237205369 2.21378966 0.129307251 2.64E-11 10.57913766 1.380864036 S(ph)PLPAGPSSCTSPR ddPTM_HeLa_Curcumin_4h_R1 1 SPLPAGPSSCTSPR 14 0 Q8N3V7-2 Q8N3V7-2 SYNPO Synaptopodin 1 0 S(1)PLPAGPSSCTSPR 183.06 8.72E-05 32096000 454.59 307.05 228.3 301.48 252.15 319.31 250.57 138.8 325.36 338.65 TRUE FALSE FALSE 418.6087218 333.5900338 236.7609988 300.2325556 249.1432759 253.0815066 257.6003198 181.119481 289.668822 350.4180623 1.194598016 0.95197728 0.675652954 0.856783905 0.710988681 0.722227345 0.735122836 0.516866853 0.826637817 1 8.45293333 -6.91834731 3.758447988 1.091654535 0.71286168 0.543541824 0.12327061 0.083334082 2.32506031 0.017042758 0.02260042 1.21E-07 6.91834731 -0.378792856 S(ph)PLPGPSEEK ddPTM_HeLa_Curcumin_4h_R1 1 SPLPGPSEEK 10 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 0 S(1)PLPGPSEEK 93.345 0.016993 11172000 1941 1982.2 1966.5 1949.9 2283.4 2261.8 2070.1 1202.9 1617.4 1779.2 TRUE FALSE FALSE 1787.367802 2153.532535 2039.38022 1941.83183 2256.171946 1792.677184 2128.181435 1569.658673 1439.975267 1841.027068 0.970853625 1.169745178 1.107740487 1.054754634 1.225496347 0.973737549 1.155975092 0.852599454 0.782158661 1 10.84629512 -7.295587672 24.83591544 0.986236426 1.08222503 0.216492453 0.118996818 691.0378864 502587.2361 0.015496464 0.01772137 5.06E-08 7.295587672 0.095988604 S(ph)PLQSVVVR ddPTM_HeLa_Curcumin_4h_R1 1 SPLQSVVVR 9 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 S(1)PLQSVVVR 107.09 0.010089 5711500 287.33 340.57 239.7 398.84 236.38 191.6 312.24 179.57 372.08 260.86 TRUE FALSE FALSE 264.5875273 370.0073532 248.5834929 397.1897058 233.5613229 151.8600002 321.000614 234.3200664 331.2637549 269.9248656 0.980226578 1.370779059 0.920935877 1.471482462 0.865282724 0.562601003 1.189222095 0.868093667 1.227244308 1 8.076414074 S(ph)PLSALAR ddPTM_HeLa_Curcumin_4h_R1 1 SPLSALAR 8 0 Q9BQG0;Q9BQG0-2;I3L1L3;I3L2H8 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 0 S(1)PLSALAR 96.665 0.017005 4202000 1158.7 963.63 922.5 1027.6 1339.5 1315.5 1171.9 781.45 1327 1089 TRUE FALSE FALSE 1066.987672 1046.921883 956.6886615 1023.348063 1323.527337 1042.650471 1204.78036 1019.710508 1181.43142 1126.842669 0.946882561 0.929075471 0.848999322 0.90815523 1.174544924 0.925284869 1.069164661 0.904927135 1.048443987 1 10.13807038 S(ph)PLSGIPVR ddPTM_HeLa_Curcumin_4h_R1 3 SPLSGIPVR 9 0 Q5M775-4;Q5M775;J3KSG2 Q5M775-4 SPECC1 Cytospin-B 1 0 S(0.999)PLS(0.001)GIPVR;S(0.999)PLS(0.001)GIPVR;S(0.999)PLS(0.001)GIPVR ;; 109.83 0.009205 115435000 2821.25 2521.5 2761.07 3092.44 2636.59 2865 1965.9 1612.85 2705.46 2255.6 TRUE FALSE FALSE 2597.945086 2739.447224 2863.397683 3079.644303 2605.150386 2270.766705 2021.057863 2104.60054 2408.677807 2333.981932 1.113095628 1.17372255 1.226829413 1.319480781 1.116182756 0.972915288 0.865926953 0.901721008 1.032003622 1 11.18857768 -5.060012118 3.386317758 1.100914344 0.88685896 0.544391069 0.092369723 0.193096299 4.355329247 0.016359604 0.049031147 8.71E-06 5.060012118 -0.214055384 T(ph)APSPLVEAK ddPTM_HeLa_Curcumin_4h_R1 2 TAPSPLVEAK 10 0 Q8TEH3;Q8TEH3-7;Q8TEH3-6;A0A0A0MS48;Q8TEH3-4;Q8TEH3-3;Q8TEH3-5;Q8TEH3-2 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 0 T(0.638)APS(0.362)PLVEAK;T(0.559)APS(0.441)PLVEAK ; 123.01 0.011728 47576000 10822.1 8507.5 9632.1 10233.4 11201.5 11661 8921.4 2157.3 9864.9 8805 TRUE FALSE FALSE 9965.519366 9242.850391 9989.074099 10191.0569 11067.92943 9242.377153 9171.710473 2815.050839 8782.745151 9110.973095 1.093793085 1.014474557 1.096378399 1.11854758 1.214791144 1.014422615 1.006666399 0.308973675 0.963974436 1 13.15338943 -4.254156437 3.89799831 1.061590398 0.231484489 0.915607824 0.068421408 0.051293389 1.537631854 0.009498885 0.121784884 5.57E-05 4.254156437 -0.830105909 down S(ph)PLTQEQLIPNLAMK ddPTM_HeLa_Curcumin_4h_R1 2 SPLTQEQLIPNLAMK 15 0 Q9UNE7;H3BTA3;Q9UNE7-2 Q9UNE7 STUB1 E3 ubiquitin-protein ligase CHIP 1 0 S(0.968)PLT(0.032)QEQLIPNLAMK;S(0.999)PLT(0.001)QEQLIPNLAMK ; 118.19 0.0014595 19419900 4073.2 3389.6 3634.6 3088.3 3786.7 4802.2 3561.8 3451.8 3612.5 3065.6 TRUE FALSE FALSE 3750.801922 3682.58192 3769.301473 3075.521433 3741.546076 3806.169588 3661.734522 4504.23793 3216.217788 3172.129372 1.182424007 1.160917948 1.18825591 0.969544767 1.179506141 1.199878423 1.154345896 1.419941434 1.013898682 1 11.6312359 -1.000000015 0.021676867 5.60E-09 2.685032862 0.443154505 0.092112047 1868.836195 3.151873698 141.7851218 267.4032054 0.099999997 1.000000015 2.685032857 S(ph)PNELVDDLFK ddPTM_HeLa_Curcumin_4h_R1 1 SPNELVDDLFK 11 0 F2Z2K0;Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5 F2Z2K0 NSFL1C NSFL1 cofactor p47 1 0 S(1)PNELVDDLFK 144.88 0.0010174 16421000 3713.8 2837.2 2862.7 2709.2 3339.7 3566.1 2688.3 4168.8 2946 2983.1 TRUE FALSE FALSE 3419.848811 3082.434926 2968.79418 2697.990048 3299.876259 2826.450662 2763.726463 5439.847929 2622.831171 3086.762503 1.107907981 0.998598021 0.961782508 0.874051711 1.06904119 0.915668329 0.895347945 1.762315022 0.849702939 1 11.59187877 -4.255806533 24.92359954 1.015082573 1.762315356 0.864401091 0.092912835 152.8796188 676423.6548 0.012214204 0.144026328 5.55E-05 4.255806533 0.747232783 S(ph)PPADAIPK ddPTM_HeLa_Curcumin_4h_R1 2 SPPADAIPK 9 0 M0R1Q8;C9JRH2;C9J3R0;C9JMJ4;C9JQZ4;C9JW69;P18754;P18754-2 M0R1Q8 RCC1 Regulator of chromosome condensation 1 0 S(1)PPADAIPK;S(1)PPADAIPK ; 97.813 0.014412 140979000 12078.3 9120.5 11047.7 10548.4 11327.2 11853.8 9986.6 10505.5 10338.8 10704 TRUE FALSE FALSE 11122.28981 9908.83538 11457.13748 10504.75352 11192.13054 9395.18826 10266.79712 13708.57859 9204.659506 11075.9632 1.004182626 0.894625162 1.034414549 0.94842799 1.010488238 0.848250223 0.926943953 1.237687264 0.83104822 1 13.43514455 S(ph)PPASPESWK ddPTM_HeLa_Curcumin_4h_R1 1 SPPASPESWK 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 S(0.926)PPAS(0.074)PESWK 121.61 0.0042881 32504000 5069.5 4184 4779.8 4158.4 4488.4 4692.6 3029 2930 5295.1 3608.1 TRUE FALSE FALSE 4668.243726 4545.646316 4956.943593 4141.193643 4434.878761 3719.301863 3113.985588 3823.343512 4714.240778 3733.481206 1.250372901 1.21753561 1.327700159 1.109204363 1.187866904 0.996202112 0.834070246 1.024069307 1.262693052 1 11.86630575 -5.106291493 4.300733241 1.147554389 0.925726257 0.513902161 0.102327692 0.181198385 5.614050384 0.017438591 0.04759423 7.83E-06 5.106291493 -0.221828132 S(ph)PPEEPPDFCCPK ddPTM_HeLa_Curcumin_4h_R1 1 SPPEEPPDFCCPK 13 0 A0A087X0G7;A0A087WUW6;A0A087X1B1;Q9Y6K9-3;Q9Y6K9;Q9Y6K9-2 A0A087X0G7 IKBKG NF-kappa-B essential modulator 1 0 S(1)PPEEPPDFCCPK 151.7 0.00047825 24629000 3198.3 3110 2953.5 3328.7 3524.8 3592.4 2060.4 2694.1 3525.5 2785.4 TRUE FALSE FALSE 2945.15118 3378.814542 3062.959308 3314.926721 3482.769062 2847.295745 2118.209279 3515.518688 3138.76147 2882.192443 1.021844044 1.172307058 1.062718527 1.150140661 1.20837492 0.987892308 0.734929857 1.219737668 1.089018701 1 11.49295095 -3.93014071 21.9763934 1.030296504 7.717022501 0.130147581 0.126795079 1412.120251 443853.2436 0.016916757 390.3227009 0.000117452 3.93014071 6.686725996 S(ph)PPEGDTTLFLSR ddPTM_HeLa_Curcumin_4h_R1 1 SPPEGDTTLFLSR 13 0 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 0 S(1)PPEGDTTLFLSR 85.672 0.016627 21733000 0 67.679 0 54.38 0 0 202.96 0 0 68.584 TRUE FALSE FALSE 0 73.52887119 0 54.15498997 0 0 208.6545114 0 0 70.9672889 0 1.036095254 0 0.763097912 0 0 2.94015052 0 0 1 6.149082288 S(ph)PPKVPIVIQDDSLPAGPPPQIR ddPTM_HeLa_Curcumin_4h_R1 2 SPPKVPIVIQDDSLPAGPPPQIR 23 1 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 0 S(1)PPKVPIVIQDDSLPAGPPPQIR;S(1)PPKVPIVIQDDSLPAGPPPQIR ; 135.06 4.84E-06 145480000 1813.47 1499.56 2201.47 1940.87 2146.36 2259.59 1828.98 2096.58 2103.93 1557.95 TRUE FALSE FALSE 1669.931936 1629.175284 2283.058415 1932.839194 2120.766059 1790.925563 1880.296256 2735.817591 1873.134143 1612.088647 1.035880961 1.010599068 1.416211459 1.198965825 1.315539355 1.110934915 1.166372743 1.69706399 1.161929989 1 10.65471536 -1 0.213905861 0.974238124 3.583147459 0.395164513 0.159232118 30.62125902 0.36211696 0.119184269 27.58123467 0.1 1 2.608909335 S(ph)PPLETR ddPTM_HeLa_Curcumin_4h_R1 1 SPPLETR 7 0 Q9BYV9 Q9BYV9 BACH2 Transcription regulator protein BACH2 1 0 S(1)PPLETR 100.02 0.019717 4800700 1447.2 999.65 1180.9 1150.2 1201.8 1500.3 1012.9 802.28 1211 1199.1 TRUE FALSE FALSE 1332.652593 1086.055292 1224.665193 1145.440777 1187.46932 1189.120868 1041.319248 1046.891479 1078.15633 1240.768636 1.074054062 0.875308466 0.987021397 0.923170319 0.957043308 0.958374377 0.839253361 0.843744312 0.868942282 1 10.27701841 -4.664766917 0.372608687 1.032913801 0.732913678 0.009891356 0.072308742 2.525424333 0.298452733 0.018596173 0.322522287 2.16E-05 4.664766917 -0.300000122 S(ph)PPLIGSESAYESFLSADDK ddPTM_HeLa_Curcumin_4h_R1 2 SPPLIGSESAYESFLSADDK 20 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(0.987)PPLIGS(0.005)ES(0.008)AYESFLSADDK;S(0.993)PPLIGS(0.007)ESAYESFLSADDK ; 122.87 4.60E-05 11582600 3242.7 2660.8 3056.4 2804.3 3955.1 3159.3 3220.5 3249.4 2601.3 2423.1 TRUE FALSE FALSE 2986.036873 2890.787696 3169.672873 2792.69655 3907.938016 2504.025567 3310.858562 4240.127102 2315.943898 2507.302545 1.190936004 1.152947299 1.264176467 1.113825117 1.558622442 0.998693027 1.320486261 1.691111075 0.923679475 1 11.29192037 -1 0.167348452 0.996660185 2.951419617 0.47648632 0.169752899 43.04189806 0.447811363 0.249393847 21.0869622 0.1 1 1.954759433 S(ph)PPLIGSESAYESFLSADDKASGR ddPTM_HeLa_Curcumin_4h_R1 2 SPPLIGSESAYESFLSADDKASGR 24 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(1)PPLIGSESAYESFLSADDKASGR;S(0.999)PPLIGS(0.001)ESAYESFLSADDKASGR ; 111.09 9.26E-07 73435000 2137 1638.43 1911.8 1991.41 2002.88 2651.4 2161.23 2416.1 2200.38 1778.91 TRUE FALSE FALSE 1967.854195 1780.048588 1982.65299 1983.170073 1978.996964 2101.469753 2221.868297 3152.757768 1959.003819 1840.72699 1.069063585 0.967035632 1.077103232 1.077384144 1.075117046 1.141652056 1.207060205 1.712778584 1.064255498 1 10.84605995 -1.194089673 0.879148971 1.034443584 199.9999994 0.963484996 0.03845308 66.66660774 0.226482659 0.006251267 26486.2533 0.063960276 1.194089673 198.9655558 S(ph)PPLPAVIR ddPTM_HeLa_Curcumin_4h_R1 2 SPPLPAVIR 9 0 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 0 S(1)PPLPAVIR;S(1)PPLPAVIR ; 109.83 0.009205 108058000 1045.15 832.35 890.7 843.97 891.22 1231.52 739.12 833.11 917.09 959.26 TRUE FALSE FALSE 962.4252747 904.2946251 923.7101255 840.4778758 880.5927836 976.0888699 759.857718 1087.121404 816.4875214 992.5942136 0.969605969 0.911041605 0.930601965 0.846748716 0.887162923 0.983371509 0.765527048 1.095232462 0.822579369 1 9.955060234 -7.40369355 1.594819086 0.989581667 0.908861609 0 0.096884438 0.439986361 2.163788497 0.014173439 0.01590073 3.95E-08 7.40369355 -0.080720058 S(ph)PPPETIK ddPTM_HeLa_Curcumin_4h_R1 1 SPPPETIK 8 0 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 0 S(1)PPPETIK 95.523 0.017673 116620000 6734.4 5610.7 5935.2 6013.8 5788.6 6573.1 5200.6 2322.5 6285 5744.4 TRUE FALSE FALSE 6201.365134 6095.663907 6155.163733 5988.916489 5719.574726 5209.764966 5346.514839 3030.619559 5595.551224 5944.017472 1.04329524 1.025512448 1.035522483 1.007553648 0.962240564 0.876472014 0.899478318 0.509860473 0.941375299 1 12.53722264 -3.929312052 0.986492858 1.018838098 7.59E-19 0.903441079 0.046661698 0.57496678 0.277812816 0.005945669 0.724323494 0.000117676 3.929312052 -1.018838098 S(ph)PPPGPDGHAK ddPTM_HeLa_Curcumin_4h_R1 1 SPPPGPDGHAK 11 0 P57081-3;P57081-2;P57081 P57081-3 WDR4 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 1 0 S(1)PPPGPDGHAK 107.99 0.0019738 0 2871.8 2719.1 2949.5 2730.8 2670.6 3198.4 2625.7 2708.2 2746.8 2694.1 TRUE FALSE FALSE 2644.494 2954.126888 3058.811065 2719.500673 2638.754839 2535.015787 2699.370075 3533.917713 2445.482912 2787.719774 0.948622607 1.059692913 1.097244814 0.975528709 0.946563878 0.909351008 0.968307539 1.267673224 0.877234123 1 11.44486983 -4.259734327 24.86065403 0.982227578 1.267673326 0.664468976 0.062064611 59.76322186 871300.1492 0.007815085 0.066930465 5.50E-05 4.259734327 0.285445748 S(ph)PPPGRDESYPR ddPTM_HeLa_Curcumin_4h_R1 1 SPPPGRDESYPR 12 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 S(1)PPPGRDESYPR 65.232 0.019033 23302000 1645.5 1502.8 1347.9 1182.2 1398.1 2255.9 1292.5 1097 1416.7 1537.5 TRUE FALSE FALSE 1515.256939 1632.695336 1397.85436 1177.30837 1381.428571 1788.000911 1328.764071 1431.47025 1261.291554 1590.928011 0.952435892 1.026253435 0.878640863 0.740013603 0.868316204 1.123872921 0.835213198 0.8997706 0.792802406 1 10.63565284 -6.747869278 24.95056269 0.98056516 0.891131718 0.00650799 0.109267782 306.339893 563247.902 0.014716428 0.020746346 1.79E-07 6.747869278 -0.089433442 S(ph)PPPTVDESADNAFHLGPLR ddPTM_HeLa_Curcumin_4h_R1 1 SPPPTVDESADNAFHLGPLR 20 0 Q96JK2-2;Q96JK2-3;Q96JK2 Q96JK2-2 DCAF5 DDB1- and CUL4-associated factor 5 1 0 S(0.927)PPPT(0.073)VDESADNAFHLGPLR 106.02 0.00015566 3421900 878.85 427.79 775.16 806.89 660.48 707.94 517.09 655.41 950.93 778 TRUE FALSE FALSE 809.2880951 464.7662614 803.8881115 803.551303 652.6042074 561.1052639 531.5981537 855.2414919 846.6153581 805.0354421 1.005282566 0.577323975 0.998574807 0.99815643 0.810652765 0.696994486 0.660341304 1.062365018 1.051649796 1 9.65290849 S(ph)PPSSSEIFTPAHEENVR ddPTM_HeLa_Curcumin_4h_R1 3 SPPSSSEIFTPAHEENVR 18 0 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 0 S(0.538)PPS(0.434)S(0.027)SEIFTPAHEENVR;S(0.938)PPS(0.059)S(0.003)SEIFTPAHEENVR;S(0.821)PPS(0.071)S(0.071)S(0.037)EIFTPAHEENVR ;; 123.61 0.00013419 108724900 3332.1 3362.2 2743.36 2892.04 2999.88 3034.52 2484.3 2283.71 3401.64 2681.32 TRUE FALSE FALSE 3068.360769 3652.813586 2845.031335 2880.073505 2964.10839 2405.126346 2554.002772 2980.002666 3028.488602 2774.49567 1.105916582 1.316568494 1.025422878 1.038052982 1.068341328 0.866869742 0.920528656 1.074070037 1.091545622 1 11.43800984 -5.298419555 20.98499806 1.069840472 0.950493521 0.281476366 0.096784612 94.58135532 53671.57028 0.014735411 0.032952529 5.03E-06 5.298419555 -0.119346951 S(ph)PPSTGSTYGSSQK ddPTM_HeLa_Curcumin_4h_R1 2 SPPSTGSTYGSSQK 14 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 S(0.997)PPS(0.001)T(0.002)GSTYGSSQK;S(0.822)PPS(0.043)T(0.133)GS(0.001)TYGSSQK ; 96.067 0.0070267 35030700 1266.54 1209.86 1367.03 1557.86 1881.83 1664.66 1510.24 1238.38 1416.4 1115.01 TRUE FALSE FALSE 1166.292023 1314.434907 1417.693334 1551.413988 1859.390406 1319.390751 1552.61327 1615.956361 1261.024464 1153.756515 1.010864951 1.139265426 1.228763016 1.344663253 1.611596886 1.143560825 1.345702711 1.400604322 1.092972779 1 10.17212308 -6.76991212 1.586656209 1.003991714 1.367352077 0.634967652 0.110851148 0.144207315 0.737013007 0.018094374 0.026351398 1.70E-07 6.76991212 0.363360362 S(ph)PPSTGSTYGSSQKEESAASGGAAYTK ddPTM_HeLa_Curcumin_4h_R1 2 SPPSTGSTYGSSQKEESAASGGAAYTK 27 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 S(0.741)PPS(0.167)T(0.042)GS(0.006)T(0.013)Y(0.01)GS(0.01)S(0.01)QKEES(0.001)AASGGAAYTK;S(0.908)PPS(0.049)T(0.03)GS(0.005)T(0.005)Y(0.001)GS(0.001)S(0.001)QKEESAASGGAAYTK ; 74.123 0.00015732 19625000 1908.17 1608.04 1776.72 1609.8 2287.29 2001.31 1819.27 1522.08 1611.6 1714.68 TRUE FALSE FALSE 1757.136331 1747.031812 1842.566806 1603.139074 2260.015561 1586.215747 1870.31382 1986.155185 1434.811512 1774.265002 0.990346047 0.984651002 1.03849583 0.903551088 1.273775652 0.89401287 1.054134426 1.119424202 0.808679374 1 10.79300579 S(ph)PPSYPGAPSSAPAR ddPTM_HeLa_Curcumin_4h_R1 2 SPPSYPGAPSSAPAR 15 0 H0Y8X4 H0Y8X4 DNPH1 1 0 S(0.997)PPS(0.003)YPGAPSSAPAR;S(0.995)PPS(0.002)YPGAPS(0.001)S(0.002)APAR ; 141.34 0.00052721 15034000 883.83 878.39 957.18 1019.42 897.23 1113.35 767.91 612.89 1111.17 893.69 TRUE FALSE FALSE 813.8739229 954.3141176 992.6539328 1015.20191 886.5311183 882.42866 789.4554879 799.7573396 989.277431 924.745661 0.880105695 1.031974691 1.07343454 1.097817436 0.958675618 0.954239308 0.853700127 0.864840327 1.069783263 1 9.852912816 -4.813470973 4.27879676 0.971225897 0.857874542 0.334081777 0.070226793 0.218847084 8.191810759 0.011227173 0.038575861 1.54E-05 4.813470973 -0.113351355 S(ph)PPT(ph)S(ph)ELMMK ddPTM_HeLa_Curcumin_4h_R1 1 SPPTSELMMK 10 0 Q9HC77;F6VUX8;Q9HC77-2 Q9HC77 CENPJ Centromere protein J 3 0 S(1)PPT(1)S(1)ELMMK 53.08 0.0088845 0 2964.5 3365.5 3114.7 3691.9 3120.7 2041.7 1910 1140.4 3817.5 3544.8 TRUE FALSE FALSE 2729.856697 3656.398824 3230.133522 3676.623896 3083.487691 1618.228405 1963.589459 1488.10271 3398.729801 3667.981536 0.744239487 0.996842211 0.880629712 1.002356162 0.840649731 0.441176813 0.535332427 0.405700709 0.926594032 1 11.84077066 -5.303330061 4.915319888 0.894554792 0.466524368 0.864111288 0.082108698 0.069162595 4.063648585 0.015308694 0.035981524 4.97E-06 5.303330061 -0.428030424 S(ph)PPTQVAISSDSAR ddPTM_HeLa_Curcumin_4h_R1 2 SPPTQVAISSDSAR 14 0 Q6ZUT6-4;Q6ZUT6;H0YM82;Q6ZUT6-3 Q6ZUT6-4 C15orf52 Uncharacterized protein C15orf52 1 0 S(1)PPTQVAISSDSAR;S(0.976)PPT(0.002)QVAIS(0.018)S(0.003)DSAR ; 130.02 0.0010916 48195000 147.61 125.26 360.15 202 349.65 342.43 244.59 181.023 405.5 257.82 TRUE FALSE FALSE 135.9265127 136.0869163 373.4974758 201.1641775 345.4806521 271.406158 251.4525371 236.2160794 361.0176645 266.7792258 0.509509361 0.51011062 1.400024588 0.754047385 1.295005828 1.017343675 0.942549167 0.885436558 1.353245042 1 8.059502518 -6.777259961 24.9997732 0.742537541 1.040553165 0.066103512 0.292887605 261.0060999 412442.3342 0.041227177 0.054282671 1.67E-07 6.777259961 0.298015624 S(ph)PPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNK ddPTM_HeLa_Curcumin_4h_R1 2 SPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVNK 37 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 0 S(0.887)PPVQPHT(0.049)PVT(0.041)IS(0.01)LGT(0.01)APS(0.003)LQNNQPVEFNHAINYVNK;S(0.855)PPVQPHT(0.127)PVT(0.013)IS(0.002)LGT(0.002)APSLQNNQPVEFNHAINYVNK ; 59.352 0.0001268 94666000 2753.5 2527.3 3110.2 1897.59 3210.9 7595.2 4337.3 3264.4 2919 2992.5 TRUE FALSE FALSE 2535.55757 2745.748551 3225.466748 1889.738275 3172.612115 6019.869904 4458.992965 4259.700533 2598.793003 3096.489152 0.818849169 0.886729588 1.041652849 0.610284158 1.024583636 1.944095267 1.440015691 1.375654919 0.839270824 1 11.59641768 -5.41699952 6.519432024 0.898596098 1.567902347 0.763989408 0.178859681 0.08660842 4.613824506 0.02470445 0.055572604 3.83E-06 5.41699952 0.669306249 S(ph)PQESTGDPGNSSSVSEGK ddPTM_HeLa_Curcumin_4h_R1 1 SPQESTGDPGNSSSVSEGK 19 0 Q9UHF7;Q9UHF7-3;Q9UHF7-2;E5RFF3;H0YAV4 Q9UHF7 TRPS1 Zinc finger transcription factor Trps1 1 0 S(1)PQESTGDPGNSSSVSEGK 137.21 3.08E-06 0 1767.6 1102.2 1490.9 1588.5 2048.8 2022.8 1559.8 1397.4 1499.8 1432.4 TRUE FALSE FALSE 1627.692595 1197.469257 1546.154066 1581.927208 2024.369398 1603.248478 1603.56379 1823.460827 1335.275692 1482.175793 1.098177829 0.807913111 1.043165104 1.067300664 1.365809243 1.081685779 1.081898515 1.230259484 0.900888881 1 10.53350085 -5.982197201 24.98517434 1.026930734 1.179728354 0.4183772 0.112375599 224.1754928 314615.2821 0.015714091 0.028480571 1.04E-06 5.982197201 0.15279762 S(ph)PQLSDFGLER ddPTM_HeLa_Curcumin_4h_R1 1 SPQLSDFGLER 11 0 Q8IX90-3;Q8IX90 Q8IX90-3 SKA3 Spindle and kinetochore-associated protein 3 1 0 S(1)PQLSDFGLER 134.06 0.0022374 25380000 1515.6 1197.3 1235.6 1197.3 1306.3 1638.3 1335.9 964.64 1621 1050.7 TRUE FALSE FALSE 1395.638661 1300.789277 1281.392423 1192.34589 1290.723226 1298.498113 1373.381759 1258.754295 1443.180356 1087.211747 1.283686149 1.196445201 1.178604285 1.096700706 1.187186608 1.194337825 1.263214606 1.157782096 1.327414241 1 10.08641723 -9.47090833 1.191958688 0.999285952 1.202220464 0 0.111958459 0.23659706 0.598007061 0.03954542 0.009588829 3.38E-10 9.47090833 0.202934512 S(ph)PQPPVEEEDEHFDDTVVCLDTYNCDLHFK ddPTM_HeLa_Curcumin_4h_R1 1 SPQPPVEEEDEHFDDTVVCLDTYNCDLHFK 30 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1W2PRI6 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 1 0 S(0.997)PQPPVEEEDEHFDDT(0.003)VVCLDTYNCDLHFK 105.17 9.22E-11 59750000 1304.5 1274.1 1306.6 1341.8 1467.9 1381.5 937.57 1047.2 1102.2 1132.7 TRUE FALSE FALSE 1201.247448 1384.227527 1355.023745 1336.247987 1450.396251 1094.961327 963.8756909 1366.486459 981.2914176 1172.061241 1.024901606 1.181019795 1.156103195 1.140083761 1.237474802 0.934218528 0.82237656 1.165883157 0.837235618 1 10.19483224 -3.913685744 21.19578764 1.040309971 9.646004436 0.074689994 0.1356053 1675.788694 418181.2445 0.01694115 11233.03164 0.000121987 3.913685744 8.605694465 S(ph)PQQTVPYVVPLSPK ddPTM_HeLa_Curcumin_4h_R1 2 SPQQTVPYVVPLSPK 15 0 Q9UQR0;H0Y6S1;B4DRC2 Q9UQR0 SCML2 Sex comb on midleg-like protein 2 1 0 S(1)PQQTVPYVVPLSPK;S(0.899)PQQT(0.1)VPYVVPLS(0.001)PK ; 218.83 2.10E-14 40440000 4279 3706.4 3958.9 4593.9 4274.2 4099.7 3175.7 1754.28 4047 2987.6 TRUE FALSE FALSE 3940.312635 4026.764701 4105.620317 4574.891659 4223.232957 3249.376007 3264.801595 2289.151896 3603.054225 3091.418878 1.274596808 1.302561982 1.328069886 1.479867931 1.36611476 1.05109535 1.056085158 0.740485837 1.165501787 1 11.59405343 -4.282954833 1.585211935 1.198452551 0.591399845 0.540288887 0.140283218 0.853869053 2.053011612 0.026386741 0.788554759 5.21E-05 4.282954833 -0.607052707 S(ph)PQVKPASTMGMGPLGK ddPTM_HeLa_Curcumin_4h_R1 2 SPQVKPASTMGMGPLGK 17 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 S(0.997)PQVKPAS(0.001)T(0.002)MGMGPLGK;S(1)PQVKPASTMGMGPLGK ; 119.76 0.0062532 63811000 2295.41 1680.46 1893.46 2042.73 2367.9 3073.7 2252.57 1281.78 1977.21 1664.81 TRUE FALSE FALSE 2113.725876 1825.711474 1963.633293 2034.277725 2339.664339 2436.179972 2315.771052 1672.588821 1760.31501 1722.662024 1.227011362 1.059819889 1.13988308 1.180891955 1.358167944 1.414194972 1.344297964 0.97093266 1.021857443 1 10.75042397 -6.02346185 3.327209213 1.108279945 1.286774462 0.30257514 0.127278014 0.255327878 5.846397282 0.020791986 0.037503145 9.47E-07 6.02346185 0.178494517 S(ph)PQVPAAQQMLNFPEK ddPTM_HeLa_Curcumin_4h_R1 1 SPQVPAAQQMLNFPEK 16 0 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 1 0 S(1)PQVPAAQQMLNFPEK 104.16 0.0031473 0 461.02 439.89 492.14 359.26 467.35 791.76 424.12 537.93 466.86 335.52 TRUE FALSE FALSE 424.5297805 477.9121315 510.3791413 357.7734773 461.7771565 627.540051 436.0196657 701.9423807 415.646626 347.179295 1.222796943 1.376557123 1.470073673 1.030515018 1.330082649 1.807538814 1.255891904 2.021844018 1.197210294 1 8.439537101 -1 0.184273246 0.990241004 4.452823764 0.487513852 0.220029848 30.40508913 0.334425264 0.242503901 29.8668259 0.1 1 3.46258276 S(ph)PRPTGSDLLPGAPILSLR ddPTM_HeLa_Curcumin_4h_R1 1 SPRPTGSDLLPGAPILSLR 19 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 0 S(0.986)PRPT(0.012)GS(0.002)DLLPGAPILSLR 111.56 0.00019069 29783000 1079.1 1058.7 1308.8 915.35 1164 1069.7 812.38 833.89 1177.7 982.03 TRUE FALSE FALSE 993.6880963 1150.209311 1357.305279 911.5625242 1150.12006 847.832162 835.1731964 1088.139222 1048.509256 1016.155469 0.977889827 1.13192257 1.335725999 0.897069938 1.131834739 0.834352801 0.821895095 1.070839311 1.031839406 1 9.988905433 -5.250804918 24.96910627 1.0280076 0.900315675 0.192472867 0.132779438 1035.610425 2431547.773 0.01889549 0.047606472 5.61E-06 5.250804918 -0.127691925 S(ph)PRSPQLSDFGLER ddPTM_HeLa_Curcumin_4h_R1 2 SPRSPQLSDFGLER 14 1 Q8IX90-3;Q8IX90 Q8IX90-3 SKA3 Spindle and kinetochore-associated protein 3 1 0 S(0.858)PRS(0.134)PQLS(0.009)DFGLER;S(0.498)PRS(0.498)PQLS(0.004)DFGLER ; 91.307 0.0039826 17033100 1561.36 1093.38 1190.39 1455.27 1120.09 1477.66 1022.1 1178.34 1757.92 1341.54 TRUE FALSE FALSE 1437.776708 1187.886895 1234.506901 1449.248478 1106.733658 1171.176659 1050.777375 1537.610442 1565.080574 1388.158415 1.03574397 0.855728627 0.889312695 1.044007991 0.79726755 0.843690926 0.756957825 1.107662083 1.127450986 1 10.4389565 -7.266668306 24.68550173 1.016879099 0.892889233 0.289073421 0.106426604 358.2919206 1691474.525 0.016085558 0.018684788 5.41E-08 7.266668306 -0.123989866 S(ph)PS(ph)LSPSPPS(ph)PLEK ddPTM_HeLa_Curcumin_4h_R1 1 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 3 0 S(0.993)PS(0.973)LS(0.037)PS(0.032)PPS(0.966)PLEK 84.41 0.0042961 0 981.75 883.84 904.5 717.97 829.38 1030.2 1020 1087 839.99 872.57 TRUE FALSE FALSE 904.0434516 960.2351913 938.0215657 714.9992304 819.4901852 816.5249073 1048.618455 1418.421296 747.8451986 902.8917426 1.001275578 1.06351088 1.038908123 0.79189918 0.907628397 0.904344196 1.161399983 1.570976042 0.828277814 1 9.818409208 -4.335889037 2.722196572 0.981522328 1.635559036 0.809493977 0.09164783 0.109083772 1.179880008 0.011506097 0.146574488 4.61E-05 4.335889037 0.654036708 S(ph)PS(ph)PAPAPAPAAAAGPPTR ddPTM_HeLa_Curcumin_4h_R1 4 SPSPAPAPAPAAAAGPPTR 19 0 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 2 0 S(1)PS(1)PAPAPAPAAAAGPPTR;S(1)PS(1)PAPAPAPAAAAGPPTR;S(1)PS(1)PAPAPAPAAAAGPPTR;S(1)PS(1)PAPAPAPAAAAGPPTR ;;; 183.6 4.46E-07 131033000 7272.4 6664.9 7398.7 7414.2 6352.3 7248.4 6005.7 5209.96 7191.1 7144.7 TRUE FALSE FALSE 6696.781866 7240.984258 7672.902331 7383.522005 6276.552971 5745.000134 6174.203778 6798.45282 6402.254321 7392.977793 0.905830107 0.979440823 1.037863571 0.998720977 0.848988479 0.777088785 0.83514437 0.919582475 0.865991283 1 12.85193986 -5.728228178 9.466276136 0.966039482 0.839374456 0.518866665 0.056226766 0.197759859 53.1733867 0.008050213 0.016022091 1.87E-06 5.728228178 -0.126665026 S(ph)PS(ph)PAPPPR ddPTM_HeLa_Curcumin_4h_R1 2 SPSPAPPPR 9 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 0 S(1)PS(1)PAPPPR;S(1)PS(1)PAPPPR ; 121.61 0.013889 599580000 7051.7 6506.2 7045.2 6540.1 7738.9 8626.7 6440.6 6628.2 6584.8 6556.5 TRUE FALSE FALSE 6493.550504 7068.566937 7306.30131 6513.038799 7646.618672 6837.425177 6621.305902 8649.107668 5862.463914 6784.337887 0.957138429 1.041894884 1.076936531 0.960010971 1.127098738 1.007824977 0.975969359 1.274863931 0.864117326 1 12.72799231 -4.258358643 24.92596917 1.000191068 1.274864036 0.592394394 0.068090875 121.2995746 981372.1235 0.007623078 0.072174721 5.52E-05 4.258358643 0.274672967 S(ph)PS(ph)PAPPPRR ddPTM_HeLa_Curcumin_4h_R1 2 SPSPAPPPRR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 0 S(1)PS(1)PAPPPRR;S(1)PS(1)PAPPPRR ; 72.29 0.01693 60930000 3229.4 3373.9 3202.1 3429.7 3276.1 4124.5 2957.9 2936.5 3293.7 3166.4 TRUE FALSE FALSE 2973.789582 3665.524882 3320.772643 3415.50881 3237.034647 3269.032207 3040.890713 3831.825332 2932.38935 3276.432164 0.907630445 1.118755005 1.013533159 1.042447589 0.987975482 0.997741459 0.928110384 1.169511572 0.894994678 1 11.67790995 -7.284102581 24.98437594 0.956381046 1.028616629 0.291078909 0.070106442 949.0266371 1046223.219 0.011621433 0.013293981 5.20E-08 7.284102581 0.072235583 S(ph)PS(ph)PASGRR ddPTM_HeLa_Curcumin_4h_R1 1 SPSPASGRR 9 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(1)PS(1)PASGRR 65.241 0.008795 0 315.21 589.62 238.21 182.85 132.96 200.36 157.73 123.86 238.26 185.8 TRUE FALSE FALSE 290.2607959 640.5841255 247.0382722 182.0934151 131.3745388 158.8030775 162.1554793 161.6243438 212.1234741 192.2565362 1.509757752 3.331923784 1.284940825 0.947137709 0.683329376 0.825995728 0.843432856 0.840670216 1.103335566 1 7.586888836 -6.256872505 4.434771171 1.441800449 0.813745315 0.273845603 0.626829469 0.297822632 15.36920379 0.105366549 0.171128547 5.54E-07 6.256872505 -0.628055134 S(ph)PS(ph)PEPIYNSEGK ddPTM_HeLa_Curcumin_4h_R1 2 SPSPEPIYNSEGK 13 0 Q15637-5;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-6 Q15637-5;Q15637-6 SF1 Splicing factor 1 2 0 S(1)PS(0.999)PEPIY(0.001)NSEGK;S(1)PS(1)PEPIYNSEGK ; 140.82 0.0022846 17814000 7382.5 7083.7 8079.1 6756.2 9099.6 8324.6 7006.3 6965.9 6417.5 6321.1 TRUE FALSE FALSE 6798.167335 7695.983464 8378.518553 6728.244635 8991.093213 6597.984122 7202.877922 9089.770843 5713.516306 6540.757754 1.039354703 1.176619553 1.280970626 1.028664397 1.374625625 1.008749195 1.101229887 1.389712199 0.873525136 1 12.67524207 -7.289883766 3.77989535 1.017039424 1.188449366 0.367410521 0.130419163 0.200944099 6.173777391 0.01960775 0.022881646 5.13E-08 7.289883766 0.171409943 S(ph)PS(ph)PSPTPEAK ddPTM_HeLa_Curcumin_4h_R1 1 SPSPSPTPEAK 11 0 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 2 0 S(1)PS(0.984)PS(0.016)PTPEAK 109.16 0.016766 92811000 4714.5 3816.8 3718.1 4023 4335.2 4643 3916.5 4218.9 4184.5 3532.7 TRUE FALSE FALSE 4341.34235 4146.707185 3855.896057 4006.353892 4283.505571 3679.989463 4026.386449 5505.223189 3725.470819 3655.461062 1.18763195 1.134386912 1.054831659 1.095991401 1.17180993 1.00671007 1.101471574 1.506027036 1.0191521 1 11.83583767 -4.262174243 6.707617527 1.092024241 1.513227015 0.799629217 0.0630576 0.044985589 13.44385398 0.010530652 0.085978173 5.47E-05 4.262174243 0.421202774 S(ph)PS(ph)PYYSR ddPTM_HeLa_Curcumin_4h_R1 1 SPSPYYSR 8 0 P62995;H7C2L4;P62995-3;H7BXF3;Q13595;Q13595-4;Q13595-3 P62995;Q13595 TRA2B;TRA2A Transformer-2 protein homolog beta;Transformer-2 protein homolog alpha 2 0 S(1)PS(1)PYYSR 136.96 0.0088547 646020000 4669.5 3709.4 3807.8 4021.6 4368.4 4505.5 3819.7 4574.1 3898.7 3637.5 TRUE FALSE FALSE 4299.904148 4030.024007 3948.920418 4004.959685 4316.309683 3571.008513 3926.870502 5968.722033 3471.022364 3763.902854 1.142405719 1.070703513 1.049155775 1.064044382 1.146764369 0.948751509 1.043297517 1.585780044 0.922187022 1 11.87801368 -4.260078832 24.72558576 1.063514557 1.585780244 0.836718461 0.071413827 27.42953439 498419.734 0.009056354 0.075990587 5.49E-05 4.260078832 0.522265687 S(ph)PSAGILR ddPTM_HeLa_Curcumin_4h_R1 2 SPSAGILR 8 0 Q99618;F5GX58;F8WDL1;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 0 S(0.998)PS(0.002)AGILR;S(0.998)PS(0.002)AGILR ; 101.46 0.014198 35646000 2647.9 2453.6 2415.1 2461.3 2769.8 2586.4 2385.2 1351.91 2902.7 2437.5 TRUE FALSE FALSE 2438.315921 2665.678251 2504.605731 2451.115793 2736.771944 2049.951485 2452.122293 1764.101136 2584.281072 2522.202944 0.966740574 1.056884918 0.993023078 0.971815452 1.08507206 0.812762308 0.972214507 0.699428704 1.024612662 1 11.30046865 -3.555613517 0.956982274 0.991905931 4.86E-15 0.631968406 0.066945581 3.010661398 0.801346103 0.009090888 4.285083811 0.000278219 3.555613517 -0.991905931 S(ph)PSAIPEQNHSLNDQAK ddPTM_HeLa_Curcumin_4h_R1 2 SPSAIPEQNHSLNDQAK 17 0 Q13129 Q13129 RLF Zinc finger protein Rlf 1 0 S(0.823)PS(0.177)AIPEQNHSLNDQAK;S(0.959)PS(0.041)AIPEQNHSLNDQAK ; 213.02 2.34E-15 26849100 4579.8 3294.83 4922.7 5028.1 4942.1 5149.6 3172.63 1883.41 4984.7 5071.3 TRUE FALSE FALSE 4217.303997 3579.620424 5105.139592 5007.295054 4883.168685 4081.514912 3261.645459 2457.653039 4437.890881 5247.527298 0.803674523 0.68215375 0.972865752 0.954219916 0.930565657 0.777797748 0.62155855 0.468344975 0.845710871 1 12.35742205 -4.692998255 1.766560999 0.897936316 0.462335374 0.698860639 0.089955101 0.212973751 1.113646531 0.015536958 0.117289482 2.03E-05 4.692998255 -0.435600943 VGS(ph)GSLDNLGR ddPTM_HeLa_Curcumin_4h_R1 2 VGSGSLDNLGR 11 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 0 VGS(0.579)GS(0.421)LDNLGR;VGS(0.627)GS(0.373)LDNLGR ; 112.02 0.0059678 37501000 4662.3 3955.8 4043.8 4536 4013.4 5146.2 4099.2 1579.42 5458.4 4357.1 TRUE FALSE FALSE 4293.274035 4297.721725 4193.666785 4517.231234 3965.542826 4078.82011 4214.21252 2060.977887 4859.627176 4508.508901 0.952260299 0.95324681 0.93016713 1.001934638 0.879568592 0.904693813 0.934724232 0.457130713 1.077879025 1 12.13843465 -4.25406435 4.207677461 0.961753618 0.413677821 0.891163714 0.052727544 0.043102972 1.693713467 0.005984326 0.071345989 5.57E-05 4.25406435 -0.548075797 down S(ph)PSAPAATSSASSSTSSYKR ddPTM_HeLa_Curcumin_4h_R1 2 SPSAPAATSSASSSTSSYKR 20 1 A0A087X0S7;A0A0C4DH00;A0A087WTU1;A0A0B4J2G4;Q15345-3;Q15345 A0A087X0S7 LRRC41 Leucine-rich repeat-containing protein 41 1 0 S(0.765)PS(0.235)APAATSSASSSTSSYKR;S(0.763)PS(0.237)APAATSSASSSTSSYKR ; 164.58 2.14E-06 19094400 4494.4 3784.7 3608.3 3926.7 3630.9 3542.86 1885.76 1774.05 4407.3 3756.9 TRUE FALSE FALSE 4138.663498 4111.832604 3742.026772 3910.452356 3587.603889 2808.0309 1938.66935 2314.949678 3923.830217 3887.451995 1.06462112 1.057719197 0.962591121 1.005916565 0.922867702 0.722331981 0.498699239 0.595492801 1.009357857 1 11.92460914 -5.186087324 1.687270942 1.027348862 0.535624017 0.95674496 0.040132485 0.052424208 0.279333316 0.006189029 0.023155773 6.51E-06 5.186087324 -0.491724845 S(ph)PSASSLSSMSSVASSVSSRPSR ddPTM_HeLa_Curcumin_4h_R1 1 SPSASSLSSMSSVASSVSSRPSR 23 1 F5H1T5;F5H6A0;J3KP58;P30622-2;P30622-1;P30622;F5H0N7 F5H1T5 CLIP1 CAP-Gly domain-containing linker protein 1 1 0 S(0.497)PS(0.497)AS(0.003)S(0.003)LSSMSSVASSVSSRPSR 61.862 0.0026955 16701000 177.37 0 0 177.94 0 133.13 144.39 65.48 182.47 225.77 TRUE FALSE FALSE 163.3309773 0 0 177.2037314 0 105.5173373 148.4411948 85.44455057 162.4534975 233.6154907 0.699144465 0 0 0.758527317 0 0.451670979 0.635408184 0.365748651 0.69538838 1 7.86799213 -7.541264114 3.141859328 0.881317281 0.326152607 0.410818401 0.262310132 0.149710276 3.065760235 0.048041978 0.051742196 2.88E-08 7.541264114 -0.555164674 LFDTPHT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 LFDTPHTPK 9 0 P30291 P30291 WEE1 Wee1-like protein kinase 1 0 LFDTPHT(1)PK 90.614 0.017706 35194000 8349.2 6489.4 7377.7 7660.3 7380.5 9038.4 6817.2 1992.8 7823.6 6891.8 TRUE FALSE FALSE 7688.35201 7050.31482 7651.124052 7628.603708 7292.492358 7163.733956 7008.472284 2600.395546 6965.370654 7131.289537 1.078115251 0.988645151 1.072894883 1.06973692 1.022605003 1.004549587 0.982777694 0.364645908 0.976733677 1 12.79994726 -4.254020492 3.810444989 1.035548559 0.291859468 0.968934957 0.035345348 0.031616065 0.876287924 0.005037453 0.066207815 5.57E-05 4.254020492 -0.743689092 down S(ph)PSDSGYSYETIGK ddPTM_HeLa_Curcumin_4h_R1 2 SPSDSGYSYETIGK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(1)PSDSGYSYETIGK;S(0.737)PS(0.247)DS(0.01)GYS(0.005)YETIGK ; 247.11 3.79E-29 60906000 4430.3 3756.3 4084.2 4010.1 5117.4 4083.1 3178.8 3388.7 3480.2 3877.5 TRUE FALSE FALSE 4079.63708 4080.977834 4235.564045 3993.507269 5056.378347 3236.219034 3267.988573 4421.89903 3098.430767 4012.242836 1.01679715 1.017131315 1.055659943 0.9953304 1.260237367 0.806586033 0.814504183 1.102101545 0.772244077 1 11.97019321 S(ph)PSDSSTASTPVAEQIER ddPTM_HeLa_Curcumin_4h_R1 2 SPSDSSTASTPVAEQIER 18 0 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 0 S(0.985)PS(0.007)DS(0.003)S(0.002)T(0.002)AS(0.002)TPVAEQIER;S(0.971)PS(0.028)DS(0.001)STASTPVAEQIER ; 164.58 1.86E-05 378040000 1457.21 1660.55 1532.76 1768.62 1801.04 1488.26 878.24 1390.83 1699.22 1254.64 TRUE FALSE FALSE 1341.870291 1804.080543 1589.565434 1761.301919 1779.563774 1179.5781 902.8810507 1814.887664 1512.819817 1298.238647 1.033608339 1.389637065 1.224401568 1.356685786 1.370752426 0.908598818 0.695466163 1.397961514 1.165286383 1 10.34233989 -7.486702459 24.56089625 1.014827101 1.178916454 0.04713748 0.221925535 653.3285644 443563.6223 0.03871051 0.043139063 3.26E-08 7.486702459 0.164089353 S(ph)PSELFAQHIVTIVHHVK ddPTM_HeLa_Curcumin_4h_R1 2 SPSELFAQHIVTIVHHVK 18 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 S(0.833)PS(0.167)ELFAQHIVTIVHHVK;S(0.5)PS(0.5)ELFAQHIVTIVHHVK ; 145.44 7.07E-05 28884000 3846.3 3334.1 3861 3095.5 3408.3 6830.1 4966.8 4382.9 3921.6 3610.7 TRUE FALSE FALSE 3541.861296 3622.284748 4004.092056 3082.691641 3367.658249 5413.460269 5106.155041 5719.226034 3491.410291 3736.171556 0.947992147 0.969517779 1.071709903 0.825093708 0.901366064 1.448932467 1.366681097 1.530771793 0.934488751 1 11.86734499 -5.257292581 24.97120661 0.96602389 1.440583753 0.910171939 0.071667901 71.73864502 431993.9574 0.009901892 0.024278595 5.53E-06 5.257292581 0.474559863 S(ph)PSFASEWDEIEK ddPTM_HeLa_Curcumin_4h_R1 3 SPSFASEWDEIEK 13 0 A0A3B3ISP1;Q92625 A0A3B3ISP1 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 0 S(0.721)PS(0.279)FASEWDEIEK;S(0.995)PS(0.005)FASEWDEIEK;S(0.858)PS(0.124)FAS(0.018)EWDEIEK ;; 181.67 0.00012494 54274900 5340.86 4465.99 4755.01 5070.06 4709.24 6467.3 4818.18 2937.64 5548.4 4924.94 TRUE FALSE FALSE 4918.125295 4852.010276 4931.234854 5049.081435 4653.085389 5125.909079 4953.365163 3833.312913 4939.754401 5096.081298 0.965079834 0.952106136 0.967652313 0.990777254 0.913071263 1.005853082 0.971994926 0.752207959 0.969324097 1 12.31517258 -4.261906403 6.620099712 0.97689904 0.748067438 0.86702035 0.025566589 0.029030537 8.098592375 0.003607595 0.029701413 5.47E-05 4.261906403 -0.228831602 S(ph)PSFGAGEGLLR ddPTM_HeLa_Curcumin_4h_R1 1 SPSFGAGEGLLR 12 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 0 S(0.808)PS(0.192)FGAGEGLLR 94.402 0.012431 48161000 1034.2 753.12 961.72 1049.8 814.22 1115.4 1066 610.67 1126.8 736.1 TRUE FALSE FALSE 952.3419787 818.216337 997.3621892 1045.456206 804.5109583 884.0534669 1095.909091 796.8604718 1003.192859 761.6794202 1.250318643 1.074226657 1.30942515 1.372567222 1.056233025 1.160663454 1.438806225 1.046188791 1.317080169 1 9.573040106 -9.378912935 0.693006379 0.969417772 1.223036784 0 0.16116766 0.982623356 0.678017522 0.153437479 0.025208298 4.18E-10 9.378912935 0.253619012 S(ph)PSFGDPQLS(ph)PEAR ddPTM_HeLa_Curcumin_4h_R1 2 SPSFGDPQLSPEAR 14 0 O95425-3;A0A6I8PIX7;O95425-2;O95425;O95425-4 O95425-3 SVIL Supervillin 2 0 S(1)PSFGDPQLS(1)PEAR;S(1)PSFGDPQLS(1)PEAR ; 164.82 0.00051901 15074600 2966.4 3139.8 3197.5 3305.2 3865.3 2926.4 2843.7 2263.96 2755.6 2703.5 TRUE FALSE FALSE 2731.60631 3411.190321 3316.002163 3291.523958 3819.208822 2319.431653 2923.486569 2954.230982 2453.317574 2797.446424 0.976464209 1.219394335 1.185367532 1.176617336 1.365248246 0.829124602 1.045055428 1.056045598 0.87698465 1 11.44989479 -7.28723392 23.893888 0.988885863 1.124306634 0.243564715 0.135805686 542.9542277 502945.361 0.022670345 0.025930083 5.16E-08 7.28723392 0.135420772 S(ph)PSFGDPQLS(ph)PEARPR ddPTM_HeLa_Curcumin_4h_R1 3 SPSFGDPQLSPEARPR 16 1 O95425-3;O95425-2 O95425-3 SVIL Supervillin 2 0 S(0.948)PS(0.052)FGDPQLS(1)PEARPR;S(0.93)PS(0.07)FGDPQLS(1)PEARPR;S(0.916)PS(0.084)FGDPQLS(1)PEARPR ;; 102.43 0.001659 77196900 7311.1 6674.9 6153.3 6437.5 6958.5 7414.9 5513.2 4294.93 6489.8 6040.3 TRUE FALSE FALSE 6732.41872 7251.848613 6381.346711 6410.863331 6875.524432 5876.966157 5667.885554 5604.434386 5777.885177 6250.199975 1.077152531 1.160258654 1.020982806 1.025705314 1.100048712 0.9402845 0.906832674 0.896680811 0.92443205 1 12.60968663 -5.104370007 4.734794952 1.048240392 0.906074333 0.504705507 0.059343954 0.114867931 4.088145841 0.007263985 0.019491765 7.86E-06 5.104370007 -0.142166059 S(ph)PSGGAAGPLLTPSQSLDGSR ddPTM_HeLa_Curcumin_4h_R1 2 SPSGGAAGPLLTPSQSLDGSR 21 0 Q96CX2 Q96CX2 KCTD12 BTB/POZ domain-containing protein KCTD12 1 0 S(1)PSGGAAGPLLTPSQSLDGSR;S(0.897)PS(0.103)GGAAGPLLTPSQSLDGSR ; 179.69 7.93E-10 62532000 1202.35 1216.01 1080.37 1294.47 1031.16 1388.94 1129.93 933.81 1183.84 1291.63 TRUE FALSE FALSE 1107.182729 1321.116486 1120.409463 1289.113826 1018.86409 1100.858187 1161.632795 1218.52437 1053.975714 1336.514046 0.828410844 0.988479313 0.838307286 0.964534439 0.762329504 0.823678726 0.869151206 0.911718342 0.788600551 1 10.38425928 -9.458522512 0.962339902 1.007565972 0.869098736 0 0.091723591 0.550133245 0.826426431 0.057227107 0.011364175 3.48E-10 9.458522512 -0.138467236 S(ph)PSGGAAGPLLTPSQSLDGSRR ddPTM_HeLa_Curcumin_4h_R1 1 SPSGGAAGPLLTPSQSLDGSRR 22 1 Q96CX2 Q96CX2 KCTD12 BTB/POZ domain-containing protein KCTD12 1 0 S(0.832)PS(0.168)GGAAGPLLTPSQSLDGSRR 93.115 0.00012305 27626000 1177.5 1374.8 1471.7 1191.7 1330.2 1877.9 1288.3 1344.5 1198 1488.9 TRUE FALSE FALSE 1084.299633 1493.631586 1526.242497 1186.769061 1314.338234 1488.402372 1324.446231 1754.431861 1066.582397 1540.639164 0.703798565 0.969488262 0.990655393 0.77030955 0.853112308 0.966094077 0.85967322 1.138768831 0.692298639 1 10.58931329 -2.046850588 1.39921642 0.87151079 145.1779293 0.345043989 0.110489701 793.8978781 3.629623102 0.017839585 366173.7743 0.008977376 2.046850588 144.3064185 LSSSS(ph)SNDSGNKVGIQLPEVELSVSTK ddPTM_HeLa_Curcumin_4h_R1 1 LSSSSSNDSGNKVGIQLPEVELSVSTK 27 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 LS(0.028)S(0.069)S(0.199)S(0.288)S(0.167)NDS(0.248)GNKVGIQLPEVELSVSTK 58.319 0.0018502 18184000 1107.6 794.65 809.91 977.05 729.09 1297 1131.9 1507 1232.2 823.63 TRUE FALSE FALSE 1019.932291 863.3360051 839.9259771 973.007226 720.3960779 1027.98758 1163.658068 1966.477363 1097.030743 852.2510812 1.19675095 1.013006641 0.985538177 1.141690809 0.8452862 1.206202729 1.365393478 2.307392042 1.287215431 1 9.735134714 -4.159605915 1.765636185 1.070712579 2.956975881 0.902432576 0.120950119 0.229288517 0.572602938 0.015687518 0.781767599 6.92E-05 4.159605915 1.886263302 up S(ph)PSGSAFGS(ph)QENLR ddPTM_HeLa_Curcumin_4h_R1 1 SPSGSAFGSQENLR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 2 0 S(0.689)PS(0.31)GS(0.005)AFGS(0.997)QENLR 86.411 0.0078839 0 1647.2 1242.9 1191.9 1330 1173.8 1946.1 1790.5 1350.9 1302.7 1240.8 TRUE FALSE FALSE 1516.822382 1350.330738 1236.072863 1324.496812 1159.803202 1542.456923 1840.736611 1762.783191 1159.797069 1283.917708 1.181401559 1.051726859 0.962735271 1.03160569 0.903331417 1.201367435 1.433687377 1.3729721 0.90332664 1 10.32633702 -4.938999388 4.180306722 1.060256629 1.398852435 0.743202841 0.090052697 0.089342893 3.166228615 0.013276925 0.042546207 1.15E-05 4.938999388 0.338595806 S(ph)PSGSAFGSQENLR ddPTM_HeLa_Curcumin_4h_R1 2 SPSGSAFGSQENLR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 S(0.885)PS(0.009)GS(0.08)AFGS(0.026)QENLR;S(0.954)PS(0.041)GS(0.005)AFGSQENLR ; 179.55 0.0001386 46064000 1077.52 919.52 1046.58 806.3 1040.9 1357.52 1085.25 967.02 1142.93 1177.67 TRUE FALSE FALSE 992.233155 998.9992115 1085.367175 802.9637442 1028.487947 1075.95505 1115.699194 1261.859946 1017.553438 1218.593945 0.814244285 0.819796632 0.890671729 0.658926419 0.843995616 0.88294797 0.915562726 1.035504855 0.835022563 1 10.25100176 -4.267123076 2.349307034 0.877912194 1.072148147 0.258199734 0.085714484 0.817893347 5.366998564 0.014881639 0.321631421 5.41E-05 4.267123076 0.194235952 S(ph)PSHSGNAGDLK ddPTM_HeLa_Curcumin_4h_R1 1 SPSHSGNAGDLK 12 0 Q9H694;Q9H694-2;A6NGY7 Q9H694 BICC1 Protein bicaudal C homolog 1 1 0 S(0.998)PS(0.002)HSGNAGDLK 160.22 0.00010226 29707000 8780.3 8427.5 7941.7 7117.9 8689 7640.3 5071.5 5245.3 7451 6919.4 TRUE FALSE FALSE 8085.32999 9155.935548 8236.026388 7088.448016 8585.38935 6055.615656 5213.792641 6844.567824 6633.643941 7159.848635 1.129259905 1.278788982 1.150307333 0.990027636 1.199102074 0.845774257 0.728198724 0.955965436 0.926506171 1 12.80571337 -5.219554639 11.11391446 1.088460447 0.831589207 0.518421045 0.111381578 0.579535564 152.2989733 0.015023924 0.038264741 6.03E-06 5.219554639 -0.256871241 S(ph)PSKPLPEVTDEYKNDVK ddPTM_HeLa_Curcumin_4h_R1 2 SPSKPLPEVTDEYKNDVK 18 2 P05455;E9PGX9;E9PFL9;E7ERC4 P05455 SSB Lupus La protein 1 0 S(0.975)PS(0.024)KPLPEVTDEYKNDVK;S(0.5)PS(0.5)KPLPEVTDEYKNDVK ; 74.062 0.0077785 115069000 4307.2 3336.4 3740.6 3882 3963.8 4626.4 4083.7 4116 3564.4 3715.7 TRUE FALSE FALSE 3966.280575 3624.783549 3879.229927 3865.937313 3916.534274 3666.83249 4198.277631 5370.949452 3173.394238 3844.820298 1.031590625 0.942770603 1.008949606 1.005492328 1.018652101 0.953707119 1.091930781 1.396931205 0.825368676 1 11.90870045 -4.289964278 2.960376908 1.006049194 1.449409482 0.791948076 0.063823897 0.055430044 0.722573019 0.003988214 0.056062489 5.13E-05 4.289964278 0.443360288 S(ph)PSLGSDLTFATR ddPTM_HeLa_Curcumin_4h_R1 1 SPSLGSDLTFATR 13 0 Q13425 Q13425 SNTB2 Beta-2-syntrophin 1 0 S(0.978)PS(0.022)LGSDLTFATR 145.61 0.00074623 14287000 486.31 275.67 416.17 274.73 331.58 449.75 280.73 189.57 378.65 424.63 TRUE FALSE FALSE 447.8180503 299.4976864 431.5936263 273.5932401 327.6261251 356.4667803 288.6065283 247.3690203 337.1130423 439.3858609 1.019190853 0.681627956 0.982265623 0.622671926 0.74564558 0.81128414 0.656840727 0.562988121 0.767236892 1 8.779344635 -6.743486039 0.725267246 1.017652983 0.669561406 0.259066566 0.134812159 0.291527513 0.311073891 0.024096705 0.040936261 1.81E-07 6.743486039 -0.348091577 AQS(ph)LEPYGTGLR ddPTM_HeLa_Curcumin_4h_R1 1 AQSLEPYGTGLR 12 0 K7ERU2;Q63ZY3-3;Q63ZY3;Q63ZY3-2 K7ERU2 KANK2 KN motif and ankyrin repeat domain-containing protein 2 1 0 AQS(0.999)LEPYGT(0.001)GLR 137.73 0.0014762 11371000 451.62 411.46 615.77 654.23 464.45 827.86 875.13 2068.1 634.49 550.21 TRUE FALSE FALSE 415.8738005 447.024769 638.5909779 651.5229696 458.9117371 656.1525041 899.6837925 2698.65417 564.8880344 569.3297565 0.730462084 0.785177244 1.121653963 1.144368377 0.806056124 1.152499929 1.580250781 4.740054667 0.992198331 1 9.153120695 -4.159550765 2.036391122 0.90609749 6.579533276 0.981731207 0.153500455 0.10023395 0.354798893 0.024521526 1.149164883 6.93E-05 4.159550765 5.673435787 up SQAAPGSS(ph)PCR ddPTM_HeLa_Curcumin_4h_R1 3 SQAAPGSSPCR 11 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 0 SQAAPGS(0.12)S(0.88)PCR;SQAAPGS(0.235)S(0.765)PCR;SQAAPGS(0.236)S(0.764)PCR ;; 116.9 0.0046026 446973400 18830.5 15646.5 16562.6 17417.2 17836.4 20872 14626.6 4799.26 18677 14448 TRUE FALSE FALSE 17340.04606 16998.91374 17176.42453 17345.13224 17623.71258 16542.91192 15036.98303 6262.532281 16628.17983 14950.06692 1.159864109 1.137045996 1.148919574 1.160204321 1.178838374 1.106544339 1.00581376 0.418896605 1.112247852 1 13.86786432 -4.253429406 3.065057404 1.101305633 0.304341275 0.942233451 0.051966024 0.091425791 1.256190139 0.010467057 0.17772292 5.58E-05 4.253429406 -0.796964359 down S(ph)PSPAVPLR ddPTM_HeLa_Curcumin_4h_R1 2 SPSPAVPLR 9 0 Q6P4R8-3;Q6P4R8;Q6P4R8-2;E9PQ59 Q6P4R8-3 NFRKB Nuclear factor related to kappa-B-binding protein 1 0 S(0.763)PS(0.237)PAVPLR;S(0.942)PS(0.058)PAVPLR ; 125.71 0.0047557 65111000 7022 5064.3 5907 6166.8 5938 6735.8 5162.6 3771.8 6730.8 5306.2 TRUE FALSE FALSE 6466.20129 5502.035526 6125.918616 6141.283416 5867.193228 5338.719152 5307.448662 4921.804457 5992.44808 5490.590055 1.177687867 1.002084561 1.115712256 1.118510643 1.068590656 0.972339785 0.966644497 0.8964072 1.091403295 1 12.42274548 -5.095478844 1.890271273 1.084488024 0.925124074 0.601264926 0.052040661 0.253884631 1.717645013 0.010399086 0.039685934 8.03E-06 5.095478844 -0.15936395 KGAANASGSS(ph)PDAPAKDAR ddPTM_HeLa_Curcumin_4h_R1 3 KGAANASGSSPDAPAKDAR 19 2 E7EPJ7;O75962-5;O75962-4;O75962 E7EPJ7 TRIO Triple functional domain protein 1 0 KGAANASGS(0.191)S(0.809)PDAPAKDAR;KGAANASGS(0.029)S(0.971)PDAPAKDAR;KGAANAS(0.003)GS(0.07)S(0.927)PDAPAKDAR ;; 173.19 2.13E-06 88538000 19618.5 13947.4 14910.9 17205.1 11758.3 17141.7 11120.7 7124.17 21378.5 18041.7 TRUE FALSE FALSE 18065.67502 15152.95111 15463.51107 17133.90985 11618.08995 13586.31819 11432.71691 9296.296637 19033.33204 18668.64773 0.967701318 0.811679096 0.828314471 0.917790624 0.622331629 0.727761238 0.612401984 0.497963043 1.019534586 1 14.18832981 -4.253275199 0.293334564 1.018807739 0.096298514 0.859626125 0.064278011 1.895262884 0.120364683 0.029829249 0.628863175 5.58E-05 4.253275199 -0.922509225 down SHS(ph)SPSQIPK ddPTM_HeLa_Curcumin_4h_R1 1 SHSSPSQIPK 10 0 Q9H792;H0YN99 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 0 S(0.037)HS(0.48)S(0.48)PS(0.003)QIPK 87.641 0.010606 37078000 8794.4 6924.1 7142.2 7907.4 7803.4 8923.9 6494 957.45 8783.6 7172.2 TRUE FALSE FALSE 8098.31396 7522.588351 7406.896215 7874.681274 7710.349552 7072.982547 6676.204162 1249.372097 7820.061055 7421.433416 1.091206174 1.013630107 0.998041187 1.061072819 1.038929964 0.953048037 0.899584189 0.168346467 1.053713025 1 12.85748215 -4.253215814 2.608646527 1.034282534 1.78E-14 0.97944019 0.037069996 0.058698988 0.502140733 0.006449826 0.133457613 5.58E-05 4.253215814 -1.034282534 down S(ph)PSPLSGHVAQAFPTK ddPTM_HeLa_Curcumin_4h_R1 1 SPSPLSGHVAQAFPTK 16 0 Q6P0Q8;A0A669KBJ4 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 0 S(0.841)PS(0.159)PLSGHVAQAFPTK 129.42 0.00047113 9326900 1041.1 1201.9 818.48 915.65 1156.9 1574.3 992.01 315.49 1219.7 1087.4 TRUE FALSE FALSE 958.6958364 1305.78688 848.8135888 911.8612829 1143.104723 1247.772434 1019.843131 411.6814487 1085.901962 1125.187069 0.852032398 1.160506476 0.754375528 0.810408605 1.015924156 1.108946653 0.906376512 0.365878226 0.96508571 1 10.13594916 -4.265307526 5.236871324 0.941870187 0.342617022 0.68015608 0.120727096 0.069107141 6.501593864 0.016754637 0.148214218 5.43E-05 4.265307526 -0.599253165 QALDYVELSPLTQAS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 2 QALDYVELSPLTQASPQR 18 0 Q9H2D6-3;Q9H2D6-2;Q9H2D6;F6WYE2;F6TR96;H0Y5J9;Q9H2D6-6;Q9H2D6-5;Q9H2D6-7 Q9H2D6-3 TRIOBP TRIO and F-actin-binding protein 1 0 QALDYVELS(0.127)PLT(0.037)QAS(0.836)PQR;QALDYVELSPLTQAS(1)PQR ; 197.94 2.00E-09 97852000 9514 7494.9 8602.2 8612.6 8695.3 10685.3 7204.2 2451.1 8970.9 7592 TRUE FALSE FALSE 8760.956861 8142.725759 8921.005099 8576.963343 8591.614227 8469.048332 7406.330463 3198.429107 7986.814714 7855.821435 1.115218432 1.036521238 1.135591634 1.091797136 1.093662107 1.078060188 0.942782435 0.407141269 1.016674676 1 12.93954642 -4.252940187 2.638280959 1.066576418 0.265020894 0.95912336 0.040970152 0.081620775 0.720657526 0.007086696 0.144919902 5.59E-05 4.252940187 -0.801555524 down S(ph)PSPPDGSPAATPEIR ddPTM_HeLa_Curcumin_4h_R1 1 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-2;O00499;O00499-9;O00499-7;O00499-4;O00499-11;O00499-3;O00499-5;O00499-10;O00499-8 O00499-6 BIN1 Myc box-dependent-interacting protein 1 1 0 S(0.991)PS(0.009)PPDGSPAATPEIR 225.21 1.22E-21 533080000 808.55 554.55 596.86 696.93 611.91 826.73 554.31 1071.1 693.15 672.36 TRUE FALSE FALSE 744.5524143 602.482831 618.9801567 694.0462883 604.6133729 655.2568788 569.8624468 1397.673459 617.1131792 695.72446 1.070182892 0.865979085 0.889691526 0.997587879 0.86904142 0.941833896 0.819092154 2.008946846 0.887008025 1 9.442372233 -4.255842352 24.99882214 0.982951726 2.008947284 0.926625013 0.09011973 127.6083214 569938.4421 0.013603237 0.159460296 5.55E-05 4.255842352 1.025995558 S(ph)PSPPLPT(ph)HIPPEPPRTPPFPAK ddPTM_HeLa_Curcumin_4h_R1 1 SPSPPLPTHIPPEPPRTPPFPAK 23 1 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 2 0 S(0.514)PS(0.557)PPLPT(0.56)HIPPEPPRT(0.368)PPFPAK 51.688 0.0086447 32107000 1798.3 1577.6 1407.3 1597.4 1678.7 1930.3 1550.3 1262.6 1862.4 1576.5 TRUE FALSE FALSE 1655.962657 1713.960714 1459.455776 1590.790382 1658.682599 1529.934021 1593.797246 1647.560928 1658.099379 1631.283258 1.015128826 1.050682465 0.894667293 0.975177287 1.016796189 0.937871466 0.977020538 1.009978445 1.016438667 1 10.6717916 -6.807847815 24.99998601 1.010609123 0.970062777 0.329777713 0.035136149 129.9934494 70026.3519 0.005480451 0.007202739 1.56E-07 6.807847815 -0.040546346 S(ph)PSPSFR ddPTM_HeLa_Curcumin_4h_R1 2 SPSPSFR 7 0 C9JEJ2;P49585 C9JEJ2 PCYT1A Choline-phosphate cytidylyltransferase A 1 0 S(0.999)PS(0.001)PSFR;S(0.999)PS(0.001)PSFR ; 124.08 0.0021511 26901000 1848.32 1806.03 2078.2 1798.01 2155.94 1941.61 1692.55 2370.5 1851.43 1767.52 TRUE FALSE FALSE 1702.023522 1962.135186 2155.21992 1790.570311 2130.231824 1538.8982 1740.038398 3093.254538 1648.332761 1828.941188 0.930605933 1.072825741 1.178397607 0.979020169 1.164735005 0.841414808 0.951391116 1.691281577 0.901249735 1 10.83679297 -4.259385263 24.91219255 0.992510886 1.691281829 0.79857303 0.103723324 54.75351994 663995.7988 0.013885611 0.122061301 5.50E-05 4.259385263 0.698770943 S(ph)PSPVLR ddPTM_HeLa_Curcumin_4h_R1 1 SPSPVLR 7 0 A0A0A0MSA7;A0A0U1RQK7;O43432;O43432-3;O43432-2 A0A0A0MSA7 EIF4G3 Eukaryotic translation initiation factor 4 gamma 3 1 0 S(0.986)PS(0.014)PVLR 101.25 0.018973 13491000 900.91 1227.7 1177.3 1315.9 1380.6 967.55 822.54 719.29 1022.2 1236.2 TRUE FALSE FALSE 829.6020229 1333.816917 1220.931774 1310.455154 1364.137247 766.8692235 845.6182586 938.5982098 910.0672174 1279.157858 0.648553279 1.042730504 0.954480924 1.02446711 1.066433856 0.599511013 0.661074201 0.733762611 0.711458099 1 10.3209786 -5.240557467 24.91368794 0.883845674 0.664411755 0.401849807 0.138185093 848.0034277 1011730.188 0.023943814 0.060973158 5.75E-06 5.240557467 -0.219433919 S(ph)PSPYYSR ddPTM_HeLa_Curcumin_4h_R1 2 SPSPYYSR 8 0 P62995;H7C2L4;P62995-3;H7BXF3;Q13595;Q13595-4;Q13595-3 P62995;Q13595 TRA2B;TRA2A Transformer-2 protein homolog beta;Transformer-2 protein homolog alpha 1 0 S(1)PSPYYSR;S(1)PSPYYSR ; 150.27 0.0019114 71281000 1683.25 1247.47 1290.12 1166.06 1517.89 1806.15 1310.83 2162.14 1406.69 1142.3 TRUE FALSE FALSE 1550.018986 1355.295748 1337.932982 1161.235153 1499.790153 1431.53413 1347.608362 2821.366533 1252.379626 1181.99484 1.311358505 1.146617314 1.131927938 0.982436736 1.268863537 1.211117073 1.140113574 2.386953341 1.059547457 1 10.20700802 -4.261166344 24.93519447 1.149810725 2.38695372 0.931451134 0.101517743 4.737378435 432410.6894 0.017484885 0.136867521 5.48E-05 4.261166344 1.237142995 S(ph)PSSDSWTCADTSTER ddPTM_HeLa_Curcumin_4h_R1 2 SPSSDSWTCADTSTER 16 0 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7;H0YIQ0 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 0 S(1)PSSDSWTCADTSTER;S(0.996)PS(0.002)S(0.002)DSWTCADTSTER ; 270.99 3.06E-52 183945000 2482.31 2660.56 2579.86 2523.81 2723.16 2455.81 1968.95 2347.17 2358.54 1977.6 TRUE FALSE FALSE 2285.832544 2890.526951 2675.471881 2513.367143 2690.688096 1946.447323 2024.193438 3062.811328 2099.814063 2046.321453 1.117044705 1.412547842 1.307454348 1.228236717 1.314890235 0.951193333 0.989186442 1.496740077 1.026140864 1 10.99881708 -7.691549318 2.441907401 1.041739434 1.227140081 0.23243205 0.161494154 0.310481451 3.884791991 0.031873034 0.032322421 2.03E-08 7.691549318 0.185400647 S(ph)PSSKPSLAVAVDSAPEVAVK ddPTM_HeLa_Curcumin_4h_R1 1 SPSSKPSLAVAVDSAPEVAVK 21 1 Q5SRN1;O60508 Q5SRN1 CDC40 Pre-mRNA-processing factor 17 1 0 S(0.414)PS(0.258)S(0.258)KPS(0.069)LAVAVDSAPEVAVK 83.934 0.0004011 38607000 3009.3 2983.2 2969.3 3161.4 2609.4 1778 1760.7 1211.1 2377.3 3527 TRUE FALSE FALSE 2771.11073 3241.054515 3079.34487 3148.318964 2578.284609 1409.222758 1810.100503 1580.358815 2116.516138 3649.562987 0.75929933 0.888066469 0.843757151 0.862656426 0.70646393 0.386134658 0.495977329 0.433026864 0.579936871 1 11.83350801 -5.483885864 2.698197593 0.879125414 0.442821292 0.679074701 0.113537838 0.084773385 1.221040526 0.013745553 0.032978507 3.28E-06 5.483885864 -0.436304122 S(ph)PSSKPSLAVAVDSAPEVAVKEDLETGVHLDPAVK ddPTM_HeLa_Curcumin_4h_R1 2 SPSSKPSLAVAVDSAPEVAVKEDLETGVHLDPAVK 35 2 Q5SRN1;O60508 Q5SRN1 CDC40 Pre-mRNA-processing factor 17 1 0 S(0.25)PS(0.25)S(0.25)KPS(0.25)LAVAVDSAPEVAVKEDLETGVHLDPAVK;S(0.423)PS(0.192)S(0.192)KPS(0.192)LAVAVDSAPEVAVKEDLETGVHLDPAVK ; 73.616 2.37E-06 66767400 2180.42 1884.26 1857.24 1821.68 1793.68 3063.65 1844.35 1479.82 2429.39 2143.61 TRUE FALSE FALSE 2007.837456 2047.127038 1926.070948 1814.142371 1772.291537 2428.214456 1896.097497 1931.010306 2162.891995 2218.100288 0.905205895 0.922919063 0.86834259 0.81788113 0.799013258 1.094727082 0.854829472 0.870569431 0.975110101 1 11.11510888 -8.829072176 0.627277833 1.003914349 0.889175508 0.200603822 0.076800033 1.012453101 0.728515912 0.060228024 0.018206936 1.48E-09 8.829072176 -0.114738841 KPNAGGS(ph)PAPVRR ddPTM_HeLa_Curcumin_4h_R1 1 KPNAGGSPAPVRR 13 2 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 KPNAGGS(1)PAPVRR 74.966 0.0083036 12637000 6721.1 5721.8 6386.3 6788.2 7142.7 6770.4 4934.1 1095.6 7388.1 5820.7 TRUE FALSE FALSE 6189.117843 6216.366896 6622.981896 6760.112227 7057.527968 5366.142722 5072.537567 1429.643396 6577.643914 6022.968892 1.027585889 1.032110079 1.099620804 1.1223887 1.171768956 0.890946445 0.842198865 0.23736523 1.09209329 1 12.55625909 -4.252932898 1.818128788 1.035614461 5.12E-21 0.922896207 0.071318273 0.178681953 0.577940344 0.010476943 0.317748769 5.59E-05 4.252932898 -1.035614461 down S(ph)PSSVTGNALWK ddPTM_HeLa_Curcumin_4h_R1 1 SPSSVTGNALWK 12 0 Q9NYB0;A0A590UJT3 Q9NYB0 TERF2IP Telomeric repeat-binding factor 2-interacting protein 1 1 0 S(0.993)PS(0.006)S(0.002)VTGNALWK 98 0.010418 34314000 667.02 557.51 541.03 487.41 575.16 554.8 516.32 595.08 523.76 475.5 TRUE FALSE FALSE 614.2246632 605.6986802 561.0810477 485.3932266 568.3015926 439.7282261 530.8065496 776.5171526 466.3048384 492.0235896 1.248364258 1.231035855 1.140353958 0.986524298 1.155029158 0.893713707 1.078823375 1.578211226 0.947728622 1 8.942583676 -4.259444127 24.64852322 1.105560907 1.578211421 0.617823074 0.116452743 84.06828353 1038448.727 0.017289723 0.151043672 5.50E-05 4.259444127 0.472650514 S(ph)PSTLLPK ddPTM_HeLa_Curcumin_4h_R1 2 SPSTLLPK 8 0 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;P27816-4;B5MEG9;H7C4C5;H0Y2V1;F8W9U4 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 S(0.998)PS(0.001)TLLPK;S(0.988)PS(0.008)T(0.003)LLPK ; 114.97 0.0098438 1832510000 8451.8 7555.6 8491.1 8800.6 8220.5 10092 8475.5 4779.2 8464.3 6437.9 TRUE FALSE FALSE 7782.831112 8208.672397 8805.787636 8764.185449 8122.475906 7998.80544 8713.299719 6236.356079 7535.787467 6661.616546 1.168309683 1.232234299 1.321869485 1.315624427 1.219295024 1.200730391 1.307985781 0.936162572 1.131225043 1 12.7016566 -8.462478111 0.787733151 1.014108415 1.226454416 0.192363236 0.111474803 0.425735159 0.550034246 0.044236851 0.022709469 3.45E-09 8.462478111 0.212346 S(ph)PSVS(ph)SPEPAEK ddPTM_HeLa_Curcumin_4h_R1 1 SPSVSSPEPAEK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(0.999)PS(0.001)VS(0.665)S(0.335)PEPAEK 104.41 0.017285 10366000 4371.8 4156.1 3865.2 3486.8 3909.2 4484.5 3342.3 2171.2 4504.7 3927.6 TRUE FALSE FALSE 4025.767417 4515.334765 4008.447712 3472.372545 3862.585343 3554.364149 3436.075943 2833.188885 4010.54568 4064.083808 0.990571949 1.111033871 0.986310298 0.854404759 0.950419707 0.874579442 0.845473692 0.697128558 0.98682652 1 11.98871444 -3.156383284 0.461778462 1.004531713 1.11E-16 0.763204446 0.05293128 4.007105319 0.270260253 0.011536741 2.764439109 0.000697616 3.156383284 -1.004531713 S(ph)PSVSS(ph)PEPAEK ddPTM_HeLa_Curcumin_4h_R1 1 SPSVSSPEPAEK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(0.993)PS(0.016)VS(0.308)S(0.683)PEPAEK 99.834 0.0048936 0 2840.9 2703.4 2552.6 2609.2 2460.8 2989.6 2289.7 1774.5 3006.7 2485.3 TRUE FALSE FALSE 2616.039767 2937.06985 2647.201601 2598.403822 2431.456567 2369.52326 2353.94282 2315.536881 2676.872532 2571.66399 1.017255667 1.14208927 1.029373049 1.010397872 0.945479883 0.921396912 0.915338407 0.900404131 1.040910688 1 11.32848644 -5.656785178 2.372925847 1.022080505 0.912905541 0.68093454 0.039447669 0.164995396 1.881747382 0.006505523 0.014590013 2.20E-06 5.656785178 -0.109174964 S(ph)PSVSSPEPAEK ddPTM_HeLa_Curcumin_4h_R1 2 SPSVSSPEPAEK 12 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.999)PS(0.001)VSSPEPAEK;S(0.996)PS(0.004)VSSPEPAEK ; 133.15 0.0020659 12837500 2961.5 2574.8 2243.69 2556.41 2495.5 2501.1 2271.29 1753.5 2493.65 2343.3 TRUE FALSE FALSE 2727.09415 2797.354239 2326.843125 2545.832253 2465.742792 1982.343667 2335.016285 2288.134078 2220.102834 2424.729501 1.124700363 1.153676828 0.959629981 1.04994485 1.016914584 0.817552501 0.963000732 0.943665707 0.915608456 1 11.2436081 -5.46711485 6.607384229 1.058418111 0.913226718 0.323424181 0.07725889 0.161080812 15.35227229 0.010189042 0.022755669 3.41E-06 5.46711485 -0.145191393 S(ph)PTDDEVTPSAVVR ddPTM_HeLa_Curcumin_4h_R1 1 SPTDDEVTPSAVVR 14 0 A0A1B0GUN5;Q5VTI5;Q9Y2H5 A0A1B0GUN5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 0 S(0.997)PT(0.003)DDEVTPSAVVR 177.21 0.00017285 4582900 1670.5 1412 991.67 1696.6 1658.7 1800.5 1330.2 1463.6 1804.1 1305.6 TRUE FALSE FALSE 1538.278162 1534.046988 1028.422163 1689.579919 1638.921086 1427.056004 1367.521832 1909.844902 1606.194744 1350.969503 1.138647585 1.135515632 0.761247504 1.250642531 1.213144399 1.056319925 1.012252186 1.41368469 1.188920061 1 10.39977939 -4.255401604 24.40150264 1.069998216 1.413684903 0.347786325 0.134171284 384.3964704 1553464.082 0.017436667 0.210491534 5.55E-05 4.255401604 0.343686687 S(ph)PTDSDVSLDSEDSGAK ddPTM_HeLa_Curcumin_4h_R1 2 SPTDSDVSLDSEDSGAK 17 0 Q8N3V7-2 Q8N3V7-2 SYNPO Synaptopodin 1 0 S(0.969)PT(0.031)DSDVSLDSEDSGAK;S(0.959)PT(0.041)DSDVSLDSEDSGAK ; 206.13 9.44E-11 103068000 5695.6 4212.2 4589.7 4056.5 4124.2 3925 2036.31 2035.53 5438 4441.7 TRUE FALSE FALSE 5244.78725 4576.283799 4759.79832 4039.715278 4075.021609 3110.910756 2093.443378 2656.153727 4841.465005 4596.048744 1.141151355 0.995699579 1.035628337 0.878953967 0.886635855 0.676866354 0.455487636 0.577921139 1.053397228 1 12.16617838 -5.349822927 0.952443777 1.062445894 0.471795347 0.916021176 0.062293507 0.145155236 0.221780226 0.011758141 0.059471834 4.47E-06 5.349822927 -0.590650548 S(ph)PTFSEELPVLGDGQQLR ddPTM_HeLa_Curcumin_4h_R1 1 SPTFSEELPVLGDGQQLR 18 0 Q8N0Z3 Q8N0Z3 SPICE1 Spindle and centriole-associated protein 1 1 0 S(1)PTFSEELPVLGDGQQLR 261.64 1.89E-43 5922300 603.01 287.05 550.67 459.84 572.22 444 325.47 275.16 426.45 447.83 TRUE FALSE FALSE 555.2811222 311.8613229 571.0783146 457.9373039 565.3966502 351.9093951 334.6018122 359.0550173 379.6695019 463.3920592 1.198296585 0.672996692 1.232386924 0.988228639 1.220125893 0.759420426 0.722070665 0.774840678 0.819326733 1 8.856089512 -5.241194982 22.73833024 1.073157013 0.749106364 0.299158853 0.173561626 167.8779239 188557.2617 0.021334537 0.054281776 5.74E-06 5.241194982 -0.324050649 S(ph)PTGPSNSFLANMGGTVAHK ddPTM_HeLa_Curcumin_4h_R1 4 SPTGPSNSFLANMGGTVAHK 20 0 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 0 S(0.734)PT(0.196)GPS(0.054)NS(0.016)FLANMGGTVAHK;S(0.735)PT(0.209)GPS(0.051)NS(0.005)FLANMGGTVAHK;S(0.761)PT(0.168)GPS(0.056)NS(0.015)FLANMGGTVAHK;S(0.793)PT(0.117)GPS(0.088)NS(0.001)FLANMGGTVAHK ;;; 137.04 5.42E-05 339318700 6960.34 6295.46 6378.96 5933.58 8098.55 8730.7 6805.5 6587.4 6551.17 5151.64 TRUE FALSE FALSE 6409.421744 6839.61151 6615.369869 5909.028418 8001.980081 6919.854405 6996.444014 8595.867935 5832.523041 5330.659107 1.202369466 1.283070512 1.241004112 1.108498649 1.501123955 1.298123603 1.312491359 1.612533791 1.094146695 1 12.38009821 -1.000000002 0.083903912 0.742595034 2.745933751 0.633454212 0.106359326 69.0361931 0.423744773 1.481244733 16.05742178 0.1 1.000000002 2.003338718 S(ph)PTKAPHLQLIEGK ddPTM_HeLa_Curcumin_4h_R1 2 SPTKAPHLQLIEGK 14 1 O43491;O43491-4;E9PHY5;E9PK52;O43491-3;O43491-2;E9PII3;A0A2R8Y5B3;H0Y5B0 O43491 EPB41L2 Band 4.1-like protein 2 1 0 S(0.5)PT(0.5)KAPHLQLIEGK;S(0.831)PT(0.169)KAPHLQLIEGK ; 75.102 0.009623 100208000 14924.4 12470.4 12968.3 12498.1 13324.3 16488.1 14374.7 10355.7 13155.1 10894.1 TRUE FALSE FALSE 13743.11799 13548.28581 13448.91661 12446.38617 13165.41642 13068.2822 14778.01539 13513.10526 11712.01844 11272.66916 1.219153848 1.201870259 1.193055204 1.104120594 1.167905864 1.159289074 1.310959736 1.198749388 1.038974734 1 13.46054154 -9.289040877 0.794373835 0.986695721 1.195559128 0.650993462 0.050841881 0.363165103 0.369537313 0.049045777 0.01038141 5.14E-10 9.289040877 0.208863407 S(ph)PTMEQAVQTASAHLPAPAAVGR ddPTM_HeLa_Curcumin_4h_R1 2 SPTMEQAVQTASAHLPAPAAVGR 23 0 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 0 S(0.951)PT(0.049)MEQAVQTASAHLPAPAAVGR;S(0.831)PT(0.169)MEQAVQTASAHLPAPAAVGR ; 130.69 4.10E-06 65355000 1044.82 1258.04 1118.99 1419.4 1624.61 1954.26 1676.64 671.29 1380 928.31 TRUE FALSE FALSE 962.1213945 1366.779372 1160.460754 1413.526899 1605.237587 1548.924447 1723.682006 875.9632308 1228.617453 960.5687034 1.001616429 1.422885596 1.208097609 1.471552106 1.671132508 1.612507717 1.794439065 0.911921477 1.279052137 1 9.907744994 -6.944579668 1.124556052 0.992213517 1.518902994 0.248901291 0.252523194 0.26865611 0.669168188 0.043185632 0.059829532 1.14E-07 6.944579668 0.526689477 S(ph)PTPESSTIASYVTLR ddPTM_HeLa_Curcumin_4h_R1 4 SPTPESSTIASYVTLR 16 0 A0JP02;B4DJX4;Q9HAU0-8;Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;Q9HAU0-5;H0YGJ6 A0JP02 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 0 S(0.999)PT(0.001)PESSTIASYVTLR;S(0.999)PT(0.001)PESSTIASYVTLR;S(1)PTPESSTIASYVTLR;S(0.998)PT(0.002)PESSTIASYVTLR ;;; 196.8 1.57E-07 37102100 2517.42 2104.13 2287.49 2146.68 2789.08 2695.66 2038.9 1255.25 1995.92 2183.34 TRUE FALSE FALSE 2318.163551 2286.001621 2372.266392 2137.797607 2755.822043 2136.54973 2096.106047 1637.969947 1776.97257 2259.210902 1.026094354 1.011858441 1.050042025 0.946258539 1.219816193 0.945706188 0.927804502 0.725018609 0.786545677 1 11.14160324 -4.29778187 1.758734909 1.022315971 0.64212421 0.378990985 0.103004227 0.388236399 1.248148053 0.00936389 0.23949134 5.04E-05 4.29778187 -0.380191761 S(ph)PTPPLFSLPEAR ddPTM_HeLa_Curcumin_4h_R1 1 SPTPPLFSLPEAR 13 0 A0A087WWS1;Q96FV9;J3KRD7;J3QQZ3;J3KT14;Q96FV9-2 A0A087WWS1 THOC1 THO complex subunit 1 1 0 S(0.998)PT(0.002)PPLFSLPEAR 116.9 0.0027926 10577000 561.45 545.96 519.21 630.8 565.94 874.94 693.79 292.14 570.19 321.91 TRUE FALSE FALSE 517.0106401 593.1503496 538.4523793 628.1899167 559.1915351 693.4675814 713.2558802 381.2121412 507.6415835 333.0963485 1.552135418 1.780717058 1.6165064 1.885910547 1.678768133 2.081882868 2.14129 1.144450075 1.524008251 1 8.379795729 -8.44877 0.483894358 0.953662111 1.826686982 0.226175902 0.305389775 0.542122991 0.264192211 0.211171363 0.081655415 3.56E-09 8.44877 0.873024871 S(ph)PTS(ph)SPTPQR ddPTM_HeLa_Curcumin_4h_R1 1 SPTSSPTPQR 10 0 A0A0D9SFB1;A0A0U1RQP1;A0A0D9SFE4;Q05193-5;Q05193-3;Q05193-2;Q05193 A0A0D9SFB1 DNM1 Dynamin-1 2 0 S(1)PT(0.01)S(0.605)S(0.384)PTPQR 115.92 0.012586 74859000 4288.6 3652.7 4235.1 4353.2 3735.1 4455.7 3398 2896.2 4283.6 3817 TRUE FALSE FALSE 3949.152785 3968.423112 4392.056532 4335.187612 3690.561372 3531.537594 3493.338735 3779.238048 3813.699797 3949.640466 0.999876525 1.004755533 1.112014263 1.097615758 0.934404385 0.894141536 0.884470059 0.95685622 0.965581508 1 11.94750562 -5.550264408 19.06493633 1.015794871 0.909951537 0.570982709 0.04711503 9.350026061 6508.957931 0.007131481 0.014264892 2.82E-06 5.550264408 -0.105843335 S(ph)PTSAPTQR ddPTM_HeLa_Curcumin_4h_R1 2 SPTSAPTQR 9 0 F8VV64;Q63HR2-5;Q63HR2-2;Q63HR2-6;Q63HR2;Q63HR2-4;H0YID7 F8VV64 TNS2 Tensin-2 1 0 S(0.998)PT(0.001)SAPTQR;S(0.998)PT(0.002)SAPTQR ; 96.171 0.015375 18181400 1206.62 1220.26 1618.78 1142.5 1488.82 1378.98 992.27 534.75 1252.78 1312.39 TRUE FALSE FALSE 1111.114754 1325.733837 1678.773411 1137.772638 1471.066794 1092.964004 1020.110426 697.7928133 1115.353168 1357.995455 0.818202115 0.976243206 1.236214308 0.837832434 1.083263415 0.804836275 0.751188395 0.513840316 0.821323197 1 10.40726294 -4.457740241 1.477195235 0.944974749 0.442432575 0.550352351 0.126704886 0.492670363 1.274847849 0.018849634 0.323480889 3.49E-05 4.457740241 -0.502542174 S(ph)PTVEPSTLPR ddPTM_HeLa_Curcumin_4h_R1 2 SPTVEPSTLPR 11 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 S(0.99)PT(0.01)VEPSTLPR;S(0.999)PT(0.001)VEPSTLPR ; 96.334 0.013327 194597000 2924.7 2732.9 2231.49 2830.33 2571.54 2965.5 2420.16 2172.12 3246.9 2972.3 TRUE FALSE FALSE 2693.206909 2969.119698 2314.190982 2818.618844 2540.876065 2350.421872 2488.063176 2834.389389 2890.723193 3075.587204 0.875672426 0.965383032 0.752438747 0.916449009 0.826143399 0.764218901 0.808971754 0.921576662 0.939893101 1 11.58664617 -8.946327165 0.310398142 1.052738969 0.822521046 0.350901123 0.065398321 1.931829966 0.29857049 0.163224014 0.036974412 1.13E-09 8.946327165 -0.230217923 S(ph)PVISRPK ddPTM_HeLa_Curcumin_4h_R1 1 SPVISRPK 8 1 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2 A0A0U1RRM6 ENAH Protein enabled homolog 1 0 S(1)PVISRPK 69.628 0.019403 89810000 4080.4 3792.7 4385.5 4399 5022.9 4852.7 3518.9 2078 4302.6 4327.6 TRUE FALSE FALSE 3757.432034 4120.524088 4548.030488 4380.798104 4963.005198 3846.195319 3617.630863 2711.572634 3830.615545 4477.983778 0.83909014 0.920173965 1.015642466 0.978297002 1.108312456 0.858912294 0.807870471 0.605534269 0.8554331 1 12.12863359 -4.41332065 1.787020652 0.94356375 0.55592572 0.656221448 0.077757455 0.347012646 1.391278891 0.012643599 0.203775173 3.86E-05 4.41332065 -0.38763803 NFELVDS(ph)SPCKK ddPTM_HeLa_Curcumin_4h_R1 1 NFELVDSSPCKK 12 1 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 1 0 NFELVDS(0.5)S(0.5)PCKK 139.77 0.0019323 45887000 3618.7 2875.6 3027.6 3383.8 2873.1 3421.6 2534 608.58 3410.2 3153 TRUE FALSE FALSE 3332.276077 3124.154051 3139.805519 3369.798732 2838.840159 2711.921591 2605.09722 794.1332404 3036.109592 3262.566515 1.02136648 0.957575588 0.962372876 1.032867442 0.870124838 0.831223387 0.798480953 0.243407525 0.930589331 1 11.6717916 -4.252611598 1.230743459 0.995834682 5.45E-38 0.9102301 0.065995698 0.280402137 0.345335234 0.009024616 0.35601801 5.59E-05 4.252611598 -0.995834682 down S(ph)PVPSAFSDQSR ddPTM_HeLa_Curcumin_4h_R1 4 SPVPSAFSDQSR 12 0 Q9UQ35;Q9UQ35-2;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.998)PVPS(0.002)AFSDQSR;S(1)PVPSAFSDQSR;S(1)PVPSAFSDQSR;S(0.999)PVPS(0.001)AFSDQSR ;;; 164.92 0.00011955 421923000 2215.56 1842.33 2134.19 2223.37 2379.75 1917.58 1453.7 1839.29 1729.35 1746.78 TRUE FALSE FALSE 2040.196088 2001.572796 2213.284959 2214.170284 2351.373036 1519.852292 1494.48691 2400.081054 1539.644632 1807.480475 1.128751384 1.107382804 1.224513896 1.225003708 1.300911998 0.84086789 0.826834331 1.327860017 0.851818126 1 10.81976435 -3.927822257 11.3706661 1.076561735 2.991167034 0.187170412 0.16499046 95378.0759 525040.8822 0.021440523 4008353.741 0.00011808 3.927822257 1.914605299 S(ph)PVPTTLPGLR ddPTM_HeLa_Curcumin_4h_R1 1 SPVPTTLPGLR 11 0 F8VV64;Q63HR2-5;Q63HR2-2;Q63HR2-6;Q63HR2;Q63HR2-4 F8VV64 TNS2 Tensin-2 1 0 S(1)PVPTTLPGLR 101.39 0.01024 5964600 986.38 903.83 965.52 1018.7 1037.7 374.96 603.12 434.59 1115.3 1199.3 TRUE FALSE FALSE 908.3069822 981.9530378 1001.303021 1014.484889 1025.326105 297.1890693 620.041924 567.0944904 992.9543803 1240.975586 0.731929776 0.791275065 0.806867623 0.817489805 0.826225848 0.23948019 0.499640711 0.456974736 0.800140141 1 10.27725902 -4.483946269 0.246017118 0.963338145 2.39E-24 0.573429774 0.140342529 4.918824746 0.264209354 0.112311667 1.438224966 3.28E-05 4.483946269 -0.963338145 S(ph)PVQLEEAPFSR ddPTM_HeLa_Curcumin_4h_R1 1 SPVQLEEAPFSR 12 0 Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4 Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 0 S(1)PVQLEEAPFSR 87.824 0.017211 5036200 208.89 102.59 235.41 249.44 292.77 374.68 145.33 319.84 361.05 323.66 TRUE FALSE FALSE 192.3561361 111.4574225 244.1345017 248.4078834 289.278909 296.9671445 149.4075687 417.3577436 321.4437183 334.9071609 0.574356594 0.332800953 0.728961725 0.741721624 0.863758506 0.886714825 0.446116375 1.246189369 0.959799478 1 8.387617414 -4.235314264 23.39209905 0.748209982 1.246190943 0.354592339 0.208606385 3491.888421 3126475.902 0.032062401 2.937103427 5.82E-05 4.235314264 0.497980961 S(ph)PVREPIDNLTPEER ddPTM_HeLa_Curcumin_4h_R1 3 SPVREPIDNLTPEER 15 1 G3XAC6;Q14498-2;Q14498;Q5QP22;Q5QP23;H0Y4X3;Q14498-3 G3XAC6 RBM39 RNA-binding protein 39 1 0 S(1)PVREPIDNLTPEER;S(1)PVREPIDNLTPEER;S(1)PVREPIDNLTPEER ;; 149.19 0.00019749 79270500 2658.14 2189.22 2241.26 2337.41 2566.76 2631.54 2074.12 2158.15 2461 2277.85 TRUE FALSE FALSE 2447.745414 2378.446422 2324.323067 2327.738417 2536.153063 2085.72894 2132.314225 2816.16 2191.034457 2357.005118 1.038498133 1.009096842 0.986134077 0.987583098 1.0760066 0.884906411 0.90467102 1.194804364 0.92958409 1 11.20273918 -6.996610137 22.10322931 1.018475347 0.997946441 0 0.086726939 119.3669799 778273.597 0.01260143 0.016495895 1.01E-07 6.996610137 -0.020528905 S(ph)PVSPLAAQGIPLPAQLTK ddPTM_HeLa_Curcumin_4h_R1 2 SPVSPLAAQGIPLPAQLTK 19 0 K7EIF1;K7EPF0;K7EQS3;K7EM48;K7EN63;Q96SI1-2;Q96SI1 K7EIF1 KCTD15 BTB/POZ domain-containing protein KCTD15 1 0 S(0.997)PVS(0.003)PLAAQGIPLPAQLTK;S(0.899)PVS(0.101)PLAAQGIPLPAQLTK ; 201.95 2.63E-13 31123000 4627.3 3870.6 4378.5 3928.6 4144.9 4776.5 3553.3 1507.24 4042.7 3647.5 TRUE FALSE FALSE 4261.044322 4205.157417 4540.771062 3912.344494 4095.474775 3785.800058 3652.996035 1966.790538 3599.225924 3774.250354 1.128977657 1.114170239 1.203092174 1.036588495 1.085109463 1.003060132 0.967873271 0.521107598 0.953626704 1 11.88197441 -4.015834719 1.536971544 1.07538791 6.37E-15 0.850623348 0.068269353 0.55932133 0.754654534 0.009864758 1.083548975 9.64E-05 4.015834719 -1.07538791 S(ph)PVSSLQIR ddPTM_HeLa_Curcumin_4h_R1 2 SPVSSLQIR 9 0 Q5JT35;P55197-1;P55197 Q5JT35 MLLT10 Protein AF-10 1 0 S(0.999)PVS(0.001)SLQIR;S(0.999)PVS(0.001)S(0.001)LQIR ; 125.23 0.0048819 20563700 647.95 315.74 605.14 485.38 487.42 739.09 650.46 349.73 649.74 560.14 TRUE FALSE FALSE 596.6640738 343.0311587 627.5670207 483.3716262 481.6078348 585.7944027 668.710157 456.361067 578.4651476 579.6048233 1.029432554 0.591836273 1.082749825 0.83396757 0.830924477 1.010678965 1.153734631 0.787365889 0.998033702 1 9.17892579 S(ph)PVSTRPLPSASQK ddPTM_HeLa_Curcumin_4h_R1 3 SPVSTRPLPSASQK 14 1 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 0 S(0.919)PVS(0.074)T(0.006)RPLPSASQK;S(0.999)PVS(0.001)TRPLPSASQK;S(1)PVSTRPLPSASQK ;; 166.79 0.0020269 967280000 8795.6 7475.7 6745 8124.2 8069.7 9091.9 7628.5 5140 9896 7800 TRUE FALSE FALSE 8099.418979 8121.866197 6994.975634 8090.584213 7973.474098 7206.137453 7842.535179 6707.162338 8810.433559 8071.049419 1.003514978 1.00629618 0.866674861 1.002420354 0.987910454 0.892837731 0.971687171 0.831014902 1.091609418 1 12.97854055 -1.283597024 0.303055965 1.003577394 1.99E-15 0.442249055 0.055506537 27.65245001 0.415362115 0.016748508 14.85332146 0.052047872 1.283597024 -1.003577394 S(ph)PVTTLLECMHK ddPTM_HeLa_Curcumin_4h_R1 2 SPVTTLLECMHK 12 0 P55265-5;P55265;P55265-4;A0A3B3ITG9;A0A3B3ISX1;A0A3B3IRQ9;P55265-3;P55265-2 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 0 S(0.999)PVT(0.001)TLLECMHK;S(0.993)PVT(0.004)T(0.003)LLECMHK ; 135.14 0.00085507 14087700 8006.5 7371.5 8307.5 7514.7 8656.7 10542.1 7592.6 5018 7730.6 7850.3 TRUE FALSE FALSE 7372.777077 8008.659613 8615.383258 7483.606163 8553.474506 8355.549626 7805.627922 6547.9651 6882.572521 8123.097341 0.90763126 0.985912058 1.060603228 0.921274958 1.052981904 1.028616213 0.960917689 0.806092162 0.84728426 1 12.98781422 -4.2674375 4.937171775 0.97396541 0.798183676 0.384586163 0.0638761 0.119004075 8.741473957 0.007840692 0.070807239 5.40E-05 4.2674375 -0.175781734 S(ph)PYQEFTDHLVK ddPTM_HeLa_Curcumin_4h_R1 1 SPYQEFTDHLVK 12 0 P15880;H0YEN5;E9PQD7 P15880 RPS2 40S ribosomal protein S2 1 0 S(0.962)PY(0.038)QEFTDHLVK 117.13 0.0018232 7249200 3373.6 3122.5 3824.2 3102.7 3985.1 4183.2 3587.2 2849.1 2923.8 2834.9 TRUE FALSE FALSE 3106.576 3392.394986 3965.928216 3089.86185 3937.580285 3315.557166 3687.847178 3717.777474 2603.066455 2933.412564 1.059031395 1.156467054 1.351984465 1.053333543 1.342320659 1.13027305 1.257186672 1.267389906 0.88738505 1 11.51836428 -7.216055459 2.625694176 1.025132778 1.228275322 0.566916126 0.095947948 0.144830401 1.928748368 0.013660697 0.016469309 6.08E-08 7.216055459 0.203142544 S(ph)QAGVSSGAPPGR ddPTM_HeLa_Curcumin_4h_R1 2 SQAGVSSGAPPGR 13 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 S(1)QAGVSSGAPPGR;S(1)QAGVSSGAPPGR ; 126.07 0.0019472 15788600 2403.49 2578.06 2482.24 2354.11 2351.94 3484.1 2821.51 1417.96 2596.54 2236.21 TRUE FALSE FALSE 2213.25123 2800.896019 2574.233998 2344.369317 2323.894652 2761.458386 2900.673977 1850.289477 2311.706058 2313.918131 0.956495046 1.210455971 1.112500033 1.01316001 1.004311527 1.193412312 1.253576753 0.799634806 0.999044014 1 11.17612211 -7.309739299 24.99506102 0.979455978 1.089927632 0.117210694 0.123025605 520.4056628 269307.1534 0.019866074 0.022717764 4.90E-08 7.309739299 0.110471653 EEFFSPDS(ph)LK ddPTM_HeLa_Curcumin_4h_R1 1 EEFFSPDSLK 10 0 O15062 O15062 ZBTB5 Zinc finger and BTB domain-containing protein 5 1 0 EEFFS(0.057)PDS(0.943)LK 152.07 0.00066021 2543800 1839.7 1416.4 1354.5 1995.8 1634.4 2043.8 1457.2 474.04 1851.9 1485.4 TRUE FALSE FALSE 1694.085804 1538.827305 1404.698962 1987.541908 1614.910847 1619.892842 1498.08511 618.5726138 1648.751203 1537.017539 1.102190288 1.001177453 0.913912122 1.293115958 1.050678217 1.053919555 0.974670146 0.402449938 1.072695113 1 10.58591791 -4.252448612 3.235063345 1.053800182 0.302513262 0.818651513 0.092362654 0.106653173 1.72731431 0.012640597 0.202624888 5.59E-05 4.252448612 -0.75128692 down S(ph)QDATFSPGSEQAEK ddPTM_HeLa_Curcumin_4h_R1 2 SQDATFSPGSEQAEK 15 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 S(1)QDATFSPGSEQAEK;S(0.997)QDAT(0.003)FSPGSEQAEK ; 163.44 2.90E-10 0 2150.3 1798.97 1883.11 2006.24 2036.88 2553.4 3206.4 2532.5 2411.9 1960.56 TRUE FALSE FALSE 1980.101486 1954.464951 1952.899713 1997.93871 2012.591536 2023.796057 3296.362954 3304.647592 2147.320604 2028.689314 0.976049646 0.963412651 0.9626411 0.984842133 0.992064937 0.997587971 1.624873228 1.628956967 1.058476815 1 10.98633222 -4.762929102 7.744262509 0.984899585 1.629807855 0.989634137 0.02599181 0.003982148 1.72858471 0.002075639 0.006945066 1.73E-05 4.762929102 0.644908271 SGIIPTS(ph)PTPYTYNK ddPTM_HeLa_Curcumin_4h_R1 1 SGIIPTSPTPYTYNK 15 0 F8VRP2;R4GN33;Q8IW41-2;Q8IW41 F8VRP2 MAPKAPK5 MAP kinase-activated protein kinase 5 1 0 SGIIPT(0.111)S(0.878)PT(0.011)PYTYNK 136.33 0.00011543 0 1334.1 1108.1 1083 1309.3 1319 1749 2222.1 4860.6 1318.8 999.83 TRUE FALSE FALSE 1228.504577 1203.879226 1123.136933 1303.882464 1303.271786 1386.237685 2284.446146 6342.574565 1174.130939 1034.574018 1.187449671 1.163647265 1.085603266 1.260308533 1.259718264 1.339911558 2.208103147 6.130614585 1.134893124 1 10.01482115 -4.157996784 1.882444131 1.123410002 8.687558684 0.995591746 0.098665355 0.05953329 0.173060348 0.017513598 0.857386781 6.95E-05 4.157996784 7.564148681 up SKYDEIFYNLAPADGKLS(ph)GSK ddPTM_HeLa_Curcumin_4h_R1 2 SKYDEIFYNLAPADGKLSGSK 21 2 Q9NZN4-2;Q9NZN4 Q9NZN4-2 EHD2 EH domain-containing protein 2 1 0 SKYDEIFY(0.001)NLAPADGKLS(0.772)GS(0.227)K;SKYDEIFYNLAPADGKLS(0.791)GS(0.209)K ; 93.269 0.00027186 593200000 8064.6 6532.4 7508.3 7554.2 7112.5 10690.1 10046 12589.7 8353.4 7564.7 TRUE FALSE FALSE 7426.2784 7097.031548 7786.564203 7522.942722 7027.688083 8472.852758 10327.86372 16428.24157 7437.052919 7827.572762 0.948733231 0.906670786 0.994761012 0.961082439 0.897811914 1.082436793 1.31942098 2.098765744 0.950109714 1 12.9343493 -4.157678169 1.516709223 0.965825866 2.753579704 0.987521466 0.038815888 0.111878644 0.193945616 0.006014523 0.320144056 6.96E-05 4.157678169 1.787753838 up S(ph)QEATEAAPSCVGDMADTPR ddPTM_HeLa_Curcumin_4h_R1 2 SQEATEAAPSCVGDMADTPR 20 0 Q9UHD8;Q9UHD8-5;Q9UHD8-2;Q9UHD8-7;Q9UHD8-3;K7ER14;K7EJL9 Q9UHD8 9-Sep Septin-9 1 0 S(0.957)QEAT(0.043)EAAPSCVGDMADTPR;S(0.998)QEAT(0.002)EAAPSCVGDMADTPR ; 183.27 9.17E-08 11215300 794.7 579.51 580.45 653.1 493.73 715.86 785.87 736.11 758.01 721.24 TRUE FALSE FALSE 731.7986564 629.6002622 601.9619876 650.3976452 487.8425922 567.3825666 807.9193971 960.5465504 674.8581994 746.3030363 0.980565026 0.843625487 0.806591905 0.871492696 0.653678959 0.760257615 1.08256212 1.287073084 0.904268329 1 9.543617745 -4.483928111 4.284527136 0.92164044 1.259900226 0.544070768 0.114781726 0.162669423 6.398850399 0.019501519 0.11233046 3.28E-05 4.483928111 0.338259786 S(ph)QEDLNEPIKR ddPTM_HeLa_Curcumin_4h_R1 1 SQEDLNEPIKR 11 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 0 S(1)QEDLNEPIKR 125.73 0.0016186 91226000 4059.1 3239.3 4068.5 4339.8 4135.1 3549.6 2617.8 3422.4 3747.8 3395.1 TRUE FALSE FALSE 3737.817952 3519.290658 4219.282189 4321.843057 4085.791633 2813.372948 2691.248423 4465.874005 3336.675717 3513.079472 1.063971932 1.001768017 1.201020991 1.230214998 1.163022831 0.800828154 0.766065341 1.271213487 0.949786574 1 11.7785205 -3.940762029 19.88117662 1.033457849 4.851749161 0.201257659 0.148070545 329.6837288 116964.3783 0.020344543 3085.189502 0.000114614 3.940762029 3.818291312 S(ph)QEGLRPR ddPTM_HeLa_Curcumin_4h_R1 2 SQEGLRPR 8 1 Q27J81-2 Q27J81-2 INF2 Inverted formin-2 1 0 S(1)QEGLRPR;S(1)QEGLRPR ; 97.597 0.0071953 60049000 3384.3 3406.9 3528 3140.5 4715.9 3650 3052.8 2147.6 3154.3 2808 TRUE FALSE FALSE 3116.429084 3701.377255 3658.750784 3127.505443 4659.665973 2892.948856 3138.453352 2802.393354 2808.281182 2905.577791 1.072567767 1.273886821 1.259216255 1.076379869 1.603696857 0.995653555 1.080147763 0.964487464 0.966513852 1 11.50460937 -7.471485088 4.514356739 1.030585341 1.183820374 0.161757752 0.173597023 0.313869486 12.7277757 0.029814312 0.033191373 3.38E-08 7.471485088 0.153235033 S(ph)QEQEVLER ddPTM_HeLa_Curcumin_4h_R1 2 SQEQEVLER 9 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 S(1)QEQEVLER;S(1)QEQEVLER ; 152.38 0.0015184 25819000 1685.53 1215.08 1482.09 1742.57 1491.29 1691.35 1858.09 1730.74 1806.38 1518.94 TRUE FALSE FALSE 1552.118522 1320.106101 1537.017559 1735.359707 1473.507341 1340.544945 1910.223005 2258.434659 1608.224633 1571.723052 0.987526727 0.839910122 0.977918824 1.104112906 0.937510803 0.852914222 1.215368701 1.436916418 1.023223927 1 10.61813131 -4.529779306 3.935178087 0.978360297 1.406020952 0.79767943 0.076118278 0.065098967 2.207999344 0.010423805 0.054543874 2.95E-05 4.529779306 0.427660655 S(ph)QES(ph)PNTPAPPLSMLR ddPTM_HeLa_Curcumin_4h_R1 1 SQESPNTPAPPLSMLR 16 0 X6R8M6;Q5T124-5;Q5T124-3;Q5T124-8;Q5T124-4;Q5T124-2;Q5T124 X6R8M6 UBXN11 UBX domain-containing protein 11 2 0 S(1)QES(0.992)PNT(0.008)PAPPLSMLR 79.489 0.012152 11680000 2046.2 1908.7 1679.1 1717.1 2194 2092.1 1386.8 1299.7 2044.1 1602.5 TRUE FALSE FALSE 1884.241111 2073.679523 1741.328923 1709.995095 2167.837983 1658.174877 1425.709876 1695.972547 1819.867344 1658.186756 1.136326234 1.25057055 1.050140412 1.031243971 1.30735454 0.999992836 0.859800545 1.022787416 1.09750445 1 10.69539079 -5.007151946 24.93817425 1.092798202 0.938444624 0.339281281 0.100180881 319.3309746 1113493.303 0.014839969 0.042139757 9.84E-06 5.007151946 -0.154353578 S(ph)QESGYYDR ddPTM_HeLa_Curcumin_4h_R1 1 SQESGYYDR 9 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 0 S(0.877)QES(0.123)GYYDR 109.24 0.0093968 59751000 1187.1 1147.9 1312 1349.5 1438.1 1471.7 1651.1 1492.2 1260.2 1243.1 TRUE FALSE FALSE 1093.139782 1247.119361 1360.623874 1343.916127 1420.951597 1166.452831 1697.425422 1947.164911 1121.959213 1286.297632 0.849834249 0.96954183 1.057783082 1.044794061 1.104683365 0.906829649 1.319621042 1.513774776 0.872239196 1 10.32900879 -1 0.570073335 0.940585447 32.11323831 0.789433345 0.090627847 44.06155534 0.346106405 0.017522931 1700.791293 0.1 1 31.17265286 ELES(ph)PLTPGK ddPTM_HeLa_Curcumin_4h_R1 2 ELESPLTPGK 10 0 O15014 O15014 ZNF609 Zinc finger protein 609 1 0 ELES(0.503)PLT(0.497)PGK;ELES(0.996)PLT(0.004)PGK ; 157.78 0.0006275 58408000 15366.9 14543.7 15307.3 15479.5 20103.9 16724.7 13542.7 3418.9 14093.3 12778.2 TRUE FALSE FALSE 14150.59365 15800.79262 15874.602 15415.44993 19864.17412 13255.80869 13922.67171 4461.306871 12547.30025 13222.2415 1.070211405 1.195016187 1.200598401 1.165872665 1.502330306 1.002538692 1.052973636 0.337409271 0.948954098 1 13.69067915 -4.252318315 4.033490646 1.0970846 0.263745448 0.706334669 0.151816398 0.113339738 3.813969943 0.021946665 0.2771401 5.59E-05 4.252318315 -0.833339152 down S(ph)QLGMGMVVHACNPSY(ph)SRG ddPTM_HeLa_Curcumin_4h_R1 1 SQLGMGMVVHACNPSYSRG 19 1 M0QY60 M0QY60 ZNF714 2 0 S(0.985)QLGMGMVVHACNPS(0.04)Y(0.688)S(0.286)RG 45.618 0.0087652 0 3490.3 3603.6 2674.7 4239.9 2995.5 1073.3 1514.8 1373.7 4102.9 3170.8 TRUE FALSE FALSE 3214.039072 3915.079127 2773.826735 4222.356417 2959.780619 850.6854814 1557.301211 1792.534806 3652.822135 3280.985064 0.979595764 1.193263319 0.845424981 1.286917293 0.902101217 0.259277462 0.474644407 0.546340435 1.113330925 1 11.67991331 -5.375617393 5.27574884 1.016043154 0.43472018 0.807202634 0.138930351 0.066630054 2.647366493 0.017836358 0.040610923 4.21E-06 5.375617393 -0.581322974 S(ph)QPCDLDAR ddPTM_HeLa_Curcumin_4h_R1 2 SQPCDLDAR 9 0 Q9NYF3 Q9NYF3 FAM53C Protein FAM53C 1 0 S(1)QPCDLDAR;S(1)QPCDLDAR ; 106.79 0.010188 21669200 4536.5 3490.2 3832.9 3719.4 4635.4 5069.8 3003.5 3105.1 3822.6 4095.3 TRUE FALSE FALSE 4177.431238 3791.877336 3974.950646 3704.010108 4580.125882 4018.266332 3087.770126 4051.830696 3403.270344 4237.61137 0.985798572 0.894814792 0.938016797 0.874079708 1.080827259 0.948238519 0.728658165 0.956159105 0.803110537 1 12.04903557 -1 0.165300429 1.017557581 0.402773217 0 0.103946778 70.28213808 0.725730318 0.132072899 10.66127354 0.1 1 -0.614784364 S(ph)QPKAPPVDDAEVDELVLQTK ddPTM_HeLa_Curcumin_4h_R1 2 SQPKAPPVDDAEVDELVLQTK 21 1 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 0 S(1)QPKAPPVDDAEVDELVLQTK;S(1)QPKAPPVDDAEVDELVLQTK ; 102.27 4.30E-05 17809200 7444.7 5259.6 6638.7 7760.9 6947.7 12681.9 9377.3 2328.9 9240.2 5378.2 TRUE FALSE FALSE 6855.444139 5714.216388 6884.736062 7728.787452 6864.853215 10051.53099 9640.4018 3038.970889 8226.573178 5565.09205 1.231865363 1.026796383 1.237128874 1.388797774 1.233556095 1.806175153 1.732298714 0.546077381 1.478245661 1 12.44218984 -6.46288146 3.010084025 1.106267173 1.383671958 0.017330668 0.346049432 0.400796886 7.177663484 0.049902023 0.077137816 3.44E-07 6.46288146 0.277404785 S(ph)QRYSGAYGASVSDEELK ddPTM_HeLa_Curcumin_4h_R1 1 SQRYSGAYGASVSDEELK 18 1 A0A286YEX5;C9JRZ6;F8WAR4;Q9NX63 A0A286YEX5 CHCHD3 MICOS complex subunit MIC19 1 0 S(0.483)QRY(0.113)S(0.404)GAYGASVSDEELK 111.11 0.0066557 21883000 1815.6 1328.9 1670.1 1649 1727.1 2054.6 1378.3 1225.2 2252.5 1661.1 TRUE FALSE FALSE 1671.893344 1443.764195 1731.995375 1642.176875 1706.505461 1628.4528 1416.971388 1598.75784 2005.406385 1718.823101 0.972696575 0.839972533 1.007663542 0.955407728 0.992833677 0.947423152 0.824384654 0.930146819 1.166732274 1 10.74720536 -1 0.137141089 1.016522051 0.584457709 0.270678796 0.077134515 78.19913521 0.712815381 0.158269661 6.623156974 0.1 1 -0.432064342 S(ph)QS(ph)IEQESQEK ddPTM_HeLa_Curcumin_4h_R1 2 SQSIEQESQEK 11 0 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 2 0 S(1)QS(0.991)IEQES(0.009)QEK;S(0.999)QS(0.782)IEQES(0.218)QEK ; 144.51 0.0024943 45237000 7187.7 5840.4 6930.4 6909.9 7765.2 8052.6 6926.9 7579.3 6835.7 5795.5 TRUE FALSE FALSE 6618.785961 6345.218152 7187.246721 6881.308665 7672.605062 6382.399988 7121.250171 9890.193679 6085.840812 5996.893194 1.103702492 1.058084236 1.198495035 1.147478943 1.27943 1.064284419 1.187489912 1.649219581 1.014832283 1 12.54999956 -1.368298817 0.968086631 1.077596806 200 0.776411867 0.08515571 215.7207024 0.737733298 0.014308544 94544.47013 0.042825376 1.368298817 198.9224032 S(ph)QEADVQDWEFR ddPTM_HeLa_Curcumin_4h_R1 2 SQEADVQDWEFR 12 0 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 S(1)QEADVQDWEFR;S(1)QEADVQDWEFR ; 218.28 2.40E-13 372110000 2888.27 1986.91 2600.54 3220.82 2897.62 4531 7101.5 16330.9 2915.06 2595.89 TRUE FALSE FALSE 2659.660382 2158.649647 2696.9183 3207.4931 2863.067774 3591.219525 7300.748977 21310.11623 2595.285211 2686.096984 0.990157987 0.803638014 1.004028639 1.194109192 1.065883991 1.336965696 2.717976685 7.93348727 0.966191923 1 11.39129568 -4.155915657 1.761540688 1.00215293 11.65696536 0.996812995 0.117197477 0.047215921 0.116345553 0.017887178 0.910400255 6.98E-05 4.155915657 10.65481243 up S(ph)QSAAVTPSSTTSSTR ddPTM_HeLa_Curcumin_4h_R1 2 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 0 S(0.972)QS(0.028)AAVTPSSTTSSTR;S(0.995)QS(0.005)AAVTPSSTTSSTR ; 174.72 4.93E-05 25874000 1113.22 1274.87 1370.63 1518.25 1294.11 1775.02 1290.32 1351.97 1498.98 1459.79 TRUE FALSE FALSE 1025.107462 1385.064082 1421.426754 1511.967884 1278.678583 1406.860843 1326.522906 1764.179429 1334.545644 1510.517594 0.678646489 0.916946673 0.941019661 1.000960128 0.846516842 0.931376668 0.878190967 1.167930408 0.883502218 1 10.56082727 -7.013270628 24.65080451 0.845594303 0.950541473 0.155930817 0.109299298 912.0775876 1694227.712 0.02295059 0.028816964 9.70E-08 7.013270628 0.10494717 S(ph)QSFSHQQPSR ddPTM_HeLa_Curcumin_4h_R1 1 SQSFSHQQPSR 11 0 B3KNS5;Q8WVR3-2;Q8WVR3-3;Q8WVR3 B3KNS5 C7orf43 Uncharacterized protein C7orf43 1 0 S(0.886)QS(0.113)FS(0.001)HQQPSR 75.316 0.015812 7906500 1807 1704.3 1680.5 1795.3 1880.2 2383.7 1758.9 1289 2160.8 1790.7 TRUE FALSE FALSE 1663.974043 1851.612098 1742.780808 1787.871524 1857.779843 1889.29375 1808.25 1682.010166 1923.765646 1852.926692 0.898024758 0.999290531 0.940555725 0.964890588 1.002619181 1.01962682 0.975888581 0.907758614 1.038230846 1 10.85559009 -5.993866389 24.05797172 0.954102635 0.980044052 0 0.046768795 247.5722039 971035.3869 0.007020243 0.012696703 1.01E-06 5.993866389 0.025941417 S(ph)QSIEQESQEK ddPTM_HeLa_Curcumin_4h_R1 2 SQSIEQESQEK 11 0 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 0 S(0.999)QS(0.001)IEQESQEK;S(0.995)QS(0.005)IEQESQEK ; 201.3 3.70E-07 56951000 5969.1 4787 4465.6 5135.7 5582.9 6334.8 5461.8 5477.4 4997.5 4771.8 TRUE FALSE FALSE 5496.639436 5200.76695 4631.099064 5114.449834 5516.327564 5020.891072 5615.043408 7147.434045 4449.286753 4937.619695 1.113216444 1.053294355 0.937921377 1.035812831 1.117203816 1.01686468 1.137196414 1.447546487 0.901099523 1 12.26960001 -4.272653766 2.614242077 1.047593646 1.524448602 0.774716248 0.068112841 0.145641277 1.299866054 0.00816472 0.149800383 5.34E-05 4.272653766 0.476854956 AYT(ph)PPPPLGPHPNLGK ddPTM_HeLa_Curcumin_4h_R1 2 AYTPPPPLGPHPNLGK 16 0 J3QS41;P42694 J3QS41 HELZ Probable helicase with zinc finger domain 1 0 AY(0.018)T(0.982)PPPPLGPHPNLGK;AY(0.057)T(0.943)PPPPLGPHPNLGK ; 101.67 0.0023518 163884000 14649.2 12818.4 13153.4 13741.3 12353.3 14556.2 10687.3 2495.75 15393 13427 TRUE FALSE FALSE 13489.70036 13926.36538 13640.87657 13684.44214 12205.99497 11537.08004 10987.15687 3256.692686 13704.42641 13893.58725 0.970929978 1.002359227 0.981810984 0.984946644 0.878534445 0.830388857 0.790807779 0.234402579 0.986385025 1 13.76213152 -4.251836856 1.379009007 0.978469524 1.55E-37 0.943962095 0.052699916 0.206728681 0.334611364 0.007567235 0.282302755 5.60E-05 4.251836856 -0.978469524 down ASSTS(ph)TPEPTR ddPTM_HeLa_Curcumin_4h_R1 3 ASSTSTPEPTR 11 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6 ENAH Protein enabled homolog 1 0 ASS(0.006)T(0.04)S(0.477)T(0.477)PEPTR;ASS(0.006)T(0.062)S(0.718)T(0.214)PEPTR;ASS(0.006)T(0.049)S(0.472)T(0.472)PEPTR ;; 150.09 0.0006279 1075999000 25673.3 21740.6 23137.9 23414 26146.9 27726.5 20150.3 5267.3 23121.5 19094.4 TRUE FALSE FALSE 23641.23121 23619.76059 23995.41093 23317.11907 25835.11529 21975.71136 20715.66319 6873.275522 20585.1293 19757.92898 1.196543992 1.195457308 1.214469945 1.180139836 1.307582152 1.112247715 1.048473411 0.34787429 1.041866752 1 14.27014411 -4.251781179 3.370039661 1.132556279 0.235892068 0.886264318 0.086001314 0.098571646 1.813867488 0.014954413 0.229736212 5.60E-05 4.251781179 -0.896664211 down S(ph)QSREEQAVLLVR ddPTM_HeLa_Curcumin_4h_R1 2 SQSREEQAVLLVR 13 1 A0A5E8;Q99501 A0A5E8 GAS2L1 GAS2-like protein 1 1 0 S(0.875)QS(0.125)REEQAVLLVR;S(0.689)QS(0.311)REEQAVLLVR ; 120.59 0.0010722 7437100 1586.41 1290.26 1373 1688.83 1405.85 1564.17 1444.67 1057.32 1766.64 1588.39 TRUE FALSE FALSE 1460.843975 1401.784325 1423.884588 1681.842069 1389.086157 1239.74351 1485.203552 1379.692001 1572.844012 1643.586434 0.888814816 0.852881416 0.866327781 1.023275706 0.845155526 0.754291642 0.903635806 0.839439881 0.956958502 1 10.68263161 -13.52287875 0.151204913 1.494737063 0.82718949 0.3189866 0.063581009 51.29759868 0.527430131 7.483475304 0.145728705 3.00E-14 13.52287875 -0.667547572 S(ph)QSYIPTSGCR ddPTM_HeLa_Curcumin_4h_R1 1 SQSYIPTSGCR 11 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 0 S(1)QSYIPTSGCR 89.46 0.01803 9729200 1020.5 960.63 1052.6 1031.3 1206.6 1232.7 1241.4 301.9 1008.9 752.28 TRUE FALSE FALSE 939.7263482 1043.662577 1091.610282 1027.032754 1192.212083 977.0241246 1276.230343 393.9479202 898.2261941 778.421674 1.207220173 1.340741929 1.402337985 1.319378414 1.531576166 1.25513479 1.639510288 0.506085498 1.153906969 1 9.60440807 -8.248619593 0.849470095 1.027617729 1.309493098 0.059536732 0.289665784 0.719075352 1.104520174 0.092662873 0.058729166 5.64E-09 8.248619593 0.281875369 S(ph)QVIEKFEALDIEK ddPTM_HeLa_Curcumin_4h_R1 1 SQVIEKFEALDIEK 14 1 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9;J3KSW8;Q6WCQ1-3 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 S(1)QVIEKFEALDIEK 71.933 0.013191 12003000 2089 1951.4 1770.4 2319.2 2397.4 3403.4 3071.8 1588.7 2766.2 2492.8 TRUE FALSE FALSE 1923.653446 2120.070321 1836.012581 2309.603765 2368.812571 2697.496476 3157.986441 2073.087317 2462.754781 2579.424614 0.74576843 0.821915984 0.711791526 0.895394947 0.918349215 1.045774496 1.224298792 0.803701455 0.954769047 1 11.33283357 -5.435333385 2.871137943 0.859783722 1.044059165 0.264162759 0.125156486 0.28919511 4.607996585 0.020196391 0.04909947 3.67E-06 5.435333385 0.184275443 S(ph)QVLERIS(ph)RMT(ph)QGDLVMSMDQLLTK ddPTM_HeLa_Curcumin_4h_R1 1 SQVLERISRMTQGDLVMSMDQLLTK 25 2 E9PDH4;Q9Y2I7 E9PDH4 PIKFYVE 1-phosphatidylinositol 3-phosphate 5-kinase 3 0 S(0.994)QVLERIS(0.983)RMT(0.939)QGDLVMS(0.083)MDQLLT(0.001)K 49.125 0.0060453 0 295.48 154.82 205.96 256.94 408.36 283.21 278.25 0 287.69 335.17 TRUE FALSE FALSE 272.0924462 168.2019509 213.5930588 255.8768504 403.4905737 224.4690536 286.0569461 0 256.1311268 346.8171326 0.784541537 0.484987433 0.615866515 0.737786073 1.163410154 0.647225966 0.824806272 0 0.738519245 1 8.438031358 -5.10196721 0.095218881 1.270392847 1.46E-17 0.127433164 0.2765475 50.66937896 1.079932811 4.270924371 11.06376357 7.91E-06 5.10196721 -1.270392847 S(ph)RAS(ph)S(ph)S(ph)GGS(ph)GGGSGGRVPK ddPTM_HeLa_Curcumin_4h_R1 1 SRASSSGGSGGGSGGRVPK 19 2 O60307 O60307 MAST3 Microtubule-associated serine/threonine-protein kinase 3 5 0 S(0.997)RAS(0.993)S(0.998)S(0.878)GGS(0.9)GGGS(0.235)GGRVPK 45.094 0.013834 36903000 502.16 758.84 530.1 667.97 387.85 461.82 577.27 323.84 513.11 757.14 TRUE FALSE FALSE 462.4135061 824.4307483 549.7459723 665.2061171 383.2251421 366.0333262 593.4666426 422.5773252 456.8231167 783.4505586 0.590226787 1.052307308 0.70169836 0.849072235 0.489150385 0.467206669 0.757503631 0.539379697 0.583091188 1 9.613698423 -5.768380834 24.98626488 0.816402544 0.570316525 0.326744922 0.16198421 150.7210715 542533.2935 0.026461861 0.048733279 1.70E-06 5.768380834 -0.246086019 S(ph)RDAT(ph)PPVSPINMEDQER ddPTM_HeLa_Curcumin_4h_R1 2 SRDATPPVSPINMEDQER 18 1 P17275 P17275 JUNB Transcription factor jun-B 2 0 S(1)RDAT(1)PPVSPINMEDQER;S(1)RDAT(1)PPVSPINMEDQER ; 86.825 0.006214 20572400 3795.3 3079.7 2839.7 3329.7 3194 3814 3088.7 2037.7 3708.8 3325.4 TRUE FALSE FALSE 3494.898 3345.895545 2944.94178 3315.922584 3155.913636 3022.933407 3175.360609 2658.98535 3301.953919 3440.957402 1.015676043 0.972373428 0.855849531 0.963662782 0.917161495 0.878515208 0.922813112 0.772745791 0.959603254 1 11.74859432 -1.304442184 0.224922292 1.021415815 8.20E-18 0.564567541 0.046175424 18.40970892 0.250900675 0.031380137 6.748884274 0.049608696 1.304442184 -1.021415815 S(ph)RDFNEECPR ddPTM_HeLa_Curcumin_4h_R1 1 SRDFNEECPR 10 1 A0A0A0MTH3;Q13418-3;Q13418-2;Q13418 A0A0A0MTH3 ILK Integrin-linked protein kinase 1 0 S(1)RDFNEECPR 72.848 0.017777 9082900 983.28 936.79 692.63 939.24 808.36 785.88 764.79 610.35 924.23 1031.5 TRUE FALSE FALSE 905.4523504 1017.761953 718.2994771 935.3536737 798.720835 622.8796293 786.2479491 796.4429053 822.8442813 1067.344548 0.848322458 0.95354584 0.672978073 0.876337145 0.748325212 0.58357878 0.736639308 0.746191009 0.770926579 1 10.05981025 -7.16981218 0.253267897 1.037011007 0.634856597 0.212077667 0.106790638 0.941408636 0.220814803 0.121304769 0.147097586 6.76E-08 7.16981218 -0.402154409 S(ph)RDRHDDYYR ddPTM_HeLa_Curcumin_4h_R1 2 SRDRHDDYYR 10 2 F8WJN3;Q16630-3;Q16630;Q16630-2 F8WJN3 CPSF6 Cleavage and polyadenylation specificity factor subunit 6 1 0 S(1)RDRHDDYYR;S(1)RDRHDDYYR ; 72.243 0.012036 12630400 591.51 576.5 624.9 527.62 704.88 608.42 457.71 627.97 819.76 695.77 TRUE FALSE FALSE 544.6913593 626.3300912 648.0593437 525.4368482 696.4747664 482.2268337 470.5521107 819.4351622 729.8343789 719.9479557 0.756570465 0.869965789 0.900147488 0.729826155 0.967395991 0.669807907 0.653591842 1.138186664 1.013732136 1 9.491748809 -9.45067788 1.122703179 1.002377224 0.821412507 0.186696415 0.139508166 0.663811552 1.464813999 0.095902185 0.022579887 3.54E-10 9.45067788 -0.180964717 S(ph)RDSGDENEPIQER ddPTM_HeLa_Curcumin_4h_R1 1 SRDSGDENEPIQER 14 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;Q8WX93-4;Q8WX93-7 Q8WX93-3 PALLD Palladin 1 0 S(0.531)RDS(0.469)GDENEPIQER 82.663 0.0072874 119590000 1028.5 1218.6 1139.5 1000.8 1169.8 1649.1 1253.4 1311.3 1368.7 1187.2 TRUE FALSE FALSE 947.0931397 1323.930354 1181.730872 996.6589548 1155.850899 1307.058071 1288.567031 1711.109334 1218.557034 1228.455112 0.770962757 1.077719765 0.961965041 0.811310845 0.940897952 1.063985211 1.048932939 1.392895286 0.991942663 1 10.26262943 -1.000010193 0.721448837 0.904149778 71.85836053 0.665801181 0.093142996 141.6358783 0.644075637 0.017656487 16287.46235 0.099997653 1.000010193 70.95421075 S(ph)RECDITK ddPTM_HeLa_Curcumin_4h_R1 1 SRECDITK 8 1 Q13427;E9PG73 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 0 S(1)RECDITK 70.488 0.018945 50709000 3204.9 3797.2 3120 2958.8 4095.1 4620 2409.7 1867.5 3286 3913.8 TRUE FALSE FALSE 2951.228783 4125.413048 3235.629945 2946.55727 4046.268607 3661.759922 2477.309697 2436.892153 2925.534021 4049.804259 0.728733686 1.018669739 0.798959589 0.72758017 0.999126957 0.904181953 0.611710971 0.601730849 0.722388993 1 11.98363646 -13.52287875 0.029328513 2.107594845 1.51E-16 0.071475689 0.145549677 1433.939978 3.378217564 182.7242919 79.89420189 3.00E-14 13.52287875 -2.107594845 S(ph)REDLSAQPVQTK ddPTM_HeLa_Curcumin_4h_R1 1 SREDLSAQPVQTK 13 1 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 0 S(0.713)REDLS(0.287)AQPVQTK 130.02 0.015774 103470000 4454.3 4669.3 4030.9 4018.8 4678.3 5245.5 4588.7 4599.5 5956.4 4138.6 TRUE FALSE FALSE 4101.737455 5072.893486 4180.2887 4002.17127 4622.514328 4157.524171 4717.446572 6001.866377 5302.997822 4282.416042 0.957809193 1.184586793 0.976151934 0.934559191 1.079417386 0.970836119 1.101585303 1.401514079 1.238319157 1 12.06420925 -4.272125461 2.342351749 0.997157486 1.49425581 0.476732575 0.103526979 0.204064854 1.340731196 0.00966462 0.204002499 5.34E-05 4.272125461 0.497098324 S(ph)REDLTAVVSVSTK ddPTM_HeLa_Curcumin_4h_R1 1 SREDLTAVVSVSTK 14 1 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;A0A3B3IRI3;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISZ5;Q9UDY2-5;A0A3B3IRV6;A0A3B3ISF1;A0A3B3IS03;A0A3B3IT83 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 S(0.934)REDLT(0.066)AVVSVSTK 159.69 0.0029327 15468000 1540.1 1949.5 1576.5 1490.8 1779.7 2213.9 2000.1 1735.8 2289.2 1573 TRUE FALSE FALSE 1418.19946 2118.006093 1634.926477 1484.631465 1758.47824 1754.712184 2056.217423 2265.037429 2038.080487 1627.661633 0.871310985 1.301257 1.004463363 0.912125367 1.080370886 1.078057103 1.263295381 1.391589863 1.252152441 1 10.6685851 -1 0.434260663 0.957617249 10.40359792 0.226806747 0.147280135 38.21172795 0.425536731 0.026860641 319.685947 0.1 1 9.445980668 S(ph)RESLNVDVVK ddPTM_HeLa_Curcumin_4h_R1 2 SRESLNVDVVK 11 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866;H0YGB8 Q07866-6 KLC1 Kinesin light chain 1 1 0 S(0.759)RES(0.241)LNVDVVK;S(0.883)RES(0.117)LNVDVVK ; 105.99 0.0035812 51238000 10465.7 8477.3 8973.7 9452.1 10050.8 11696.8 8766.8 6395.7 10476.8 9050.1 TRUE FALSE FALSE 9637.328802 9210.040038 9306.273216 9412.989715 9930.950774 9270.75183 9012.772813 8345.719488 9327.521252 9364.590301 1.029124446 0.983496313 0.993772596 1.005168343 1.060478938 0.989979437 0.962431086 0.891199638 0.996041573 1 13.19300016 -4.399804228 1.801745281 1.012291469 0.871396223 0.740765035 0.021256071 0.24147458 0.970293877 0.003122163 0.052272762 3.98E-05 4.399804228 -0.140895245 S(ph)RFSGGFGAR ddPTM_HeLa_Curcumin_4h_R1 1 SRFSGGFGAR 10 1 A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8Y5G6;A0A2R8YFR4;A0A2R8YDT5;A0A0J9YVQ7 A0A2R8YCW1 1 0 S(0.999)RFS(0.001)GGFGAR 75.652 0.016251 36812000 3325.4 2498.6 2689.9 3125.3 3461.1 6081.5 4167.5 1750.3 3424.7 2504.5 TRUE FALSE FALSE 3062.191081 2714.56785 2789.59006 3112.368337 3419.828643 4820.128347 4284.428834 2283.958413 3049.018978 2591.531189 1.181614597 1.047476435 1.076425425 1.200976608 1.319617012 1.859953825 1.653242243 0.881316197 1.176531848 1 11.33958904 -5.729723688 2.803519956 1.086850443 1.492883296 0.300130974 0.23963152 0.209944249 3.370657238 0.034569555 0.072296193 1.86E-06 5.729723688 0.406032852 S(ph)RFTPELQPK ddPTM_HeLa_Curcumin_4h_R1 1 SRFTPELQPK 10 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 S(0.996)RFT(0.004)PELQPK 106.79 0.0039303 21731000 7743.3 5404.5 6407.1 6680.6 6577.9 11157 8537.6 3060 7605.8 5093.8 TRUE FALSE FALSE 7130.409634 5871.640898 6644.552762 6652.957447 6499.462839 8842.912435 8777.142078 3992.979913 6771.462769 5270.809171 1.352811191 1.113992313 1.26063239 1.262226962 1.233105322 1.677714398 1.66523617 0.757564879 1.284710288 1 12.36380875 -11.55659754 0.287946488 0.296269077 1.34453954 0 0.265259951 20.07489865 0.730687811 8.451292425 0.118681505 2.78E-12 11.55659754 1.048270463 S(ph)RLSSSS(ph)SNDSGNK ddPTM_HeLa_Curcumin_4h_R1 1 SRLSSSSSNDSGNK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 S(0.926)RLS(0.044)S(0.029)S(0.007)S(0.533)S(0.382)NDS(0.079)GNK 128.74 0.0045252 4364500 3650.4 6980.7 4686.1 4409.7 5244.2 4641.2 2909.9 1367.4 3069 3372.6 TRUE FALSE FALSE 3361.466988 7584.080603 4859.770988 4391.45383 5181.66634 3678.562803 2991.543962 1784.313965 2732.338378 3489.797599 0.963226919 2.173215033 1.392565285 1.258369205 1.48480426 1.054090588 0.857225635 0.511294399 0.782950386 1 11.76892765 -4.490821288 2.124561401 1.157375525 0.480201177 0.26545066 0.375990423 0.549833653 3.81286708 0.057443057 0.587595116 3.23E-05 4.490821288 -0.677174348 S(ph)RLSSSSS(ph)NDSGNK ddPTM_HeLa_Curcumin_4h_R1 1 SRLSSSSSNDSGNK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 S(0.694)RLS(0.261)S(0.045)S(0.095)S(0.213)S(0.479)NDS(0.213)GNK 104.16 0.015409 3770900 4444.1 7438.3 6082.9 4454.3 5798.8 5252.1 3325.2 1888.6 4039.5 4299.5 TRUE FALSE FALSE 4092.344796 8081.233508 6308.337625 4435.869287 5729.653097 4162.755257 3418.496163 2464.425446 3596.376956 4448.907305 0.919853914 1.816453559 1.417952138 0.997069389 1.287878732 0.935680375 0.768390063 0.553939491 0.808373092 1 12.11923532 -4.672886981 2.103995809 1.083832901 0.56915727 0.318724668 0.285745575 0.405836063 3.202878745 0.043819807 0.287546564 2.12E-05 4.672886981 -0.514675631 S(ph)RLTPVS(ph)PESSSTEEK ddPTM_HeLa_Curcumin_4h_R1 1 SRLTPVSPESSSTEEK 16 1 Q13501;E7EMC7;Q13501-2 Q13501 SQSTM1 Sequestosome-1 2 0 S(0.972)RLT(0.028)PVS(0.994)PES(0.006)SSTEEK 120.15 0.00067729 410580000 10089 8804 9302.4 8529.5 7581.8 6532.2 3587.5 3640.4 10429 8106.3 TRUE FALSE FALSE 9290.445004 9564.97853 9647.155127 8494.207189 7491.391987 5177.348087 3688.155595 4750.341202 9284.964792 8387.993322 1.107588508 1.140317852 1.150114784 1.012662608 0.893108959 0.617233215 0.439694627 0.566326298 1.106935167 1 13.03411 -5.335970709 1.869009629 1.066403755 0.497089124 0.950043645 0.056190508 0.062272936 0.416720031 0.009848093 0.03003575 4.61E-06 5.335970709 -0.56931463 S(ph)RNSPLLER ddPTM_HeLa_Curcumin_4h_R1 1 SRNSPLLER 9 1 E7ETY4;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E9PC69;Q7KZI7-14;Q7KZI7-6;Q7KZI7-10;Q7KZI7-12;Q7KZI7-8;Q7KZI7-11;Q7KZI7-9;Q7KZI7-3;Q7KZI7-4;Q7KZI7-5;Q7KZI7-2;Q7KZI7-7;Q7KZI7 E7ETY4 MARK2 Serine/threonine-protein kinase MARK2 1 0 S(0.995)RNS(0.005)PLLER 93.839 0.0073189 390040000 1596.3 1826.5 1702.6 1768.2 1800.5 1919.4 1604 739.24 1866.9 1651.2 TRUE FALSE FALSE 1469.951171 1984.374521 1765.699854 1760.883657 1779.030213 1521.294804 1649.003923 964.630873 1662.105741 1708.579077 0.860335463 1.161418016 1.033431743 1.030612911 1.041233758 0.89038595 0.965131755 0.564580759 0.972800009 1 10.73858131 -4.26122783 8.388778183 0.966915626 0.561988947 0.694636635 0.0837747 0.046371987 47.51164178 0.013248436 0.104818769 5.48E-05 4.26122783 -0.404926679 S(ph)RNTDEMVELR ddPTM_HeLa_Curcumin_4h_R1 4 SRNTDEMVELR 11 1 P61978-3;P61978;P61978-2;Q5T6W2;S4R457 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 0 S(0.976)RNT(0.024)DEMVELR;S(1)RNTDEMVELR;S(0.573)RNT(0.427)DEMVELR;S(1)RNTDEMVELR ;;; 113.37 0.0023919 39749600 14838.88 11332.56 11357.66 12750.92 13230 15727.59 11899.41 10182.88 15083.49 12122.9 TRUE FALSE FALSE 13664.36699 12312.09599 11778.58487 12698.16007 13072.24089 12465.51055 12233.27542 13287.59324 13428.86888 12544.16987 1.089300219 0.981499463 0.938968859 1.012275838 1.042096928 0.993729412 0.97521602 1.059264453 1.070526708 1 13.61472938 -7.231930593 24.79548058 1.042169556 0.998901537 0.267794776 0.038697041 851.5484165 715534.883 0.007520917 0.009210421 5.86E-08 7.231930593 -0.043268019 S(ph)RPTSFADELAAR ddPTM_HeLa_Curcumin_4h_R1 2 SRPTSFADELAAR 13 1 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1-5;A0A0A0MT65;Q641Q2;F8W7U3;E7ESD2;Q641Q2-2;A0A087WYF6 A0A0A0MR88;Q641Q2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 0 S(0.943)RPT(0.042)S(0.015)FADELAAR;S(0.968)RPT(0.024)S(0.008)FADELAAR ; 89.877 0.0054944 11489200 2451.85 1731.01 1555.32 2321.52 2558.45 2428.77 2053.24 1755.95 2294.41 2013.08 TRUE FALSE FALSE 2257.783485 1880.630791 1612.961527 2311.914165 2527.942155 1925.015724 2110.848388 2291.331072 2042.718963 2083.03438 1.083891609 0.902832334 0.774332648 1.109878064 1.213586381 0.924140159 1.01335264 1.099996761 0.980645823 1 11.02447094 S(ph)RPVSMDAR ddPTM_HeLa_Curcumin_4h_R1 1 SRPVSMDAR 9 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 0 S(0.999)RPVS(0.001)MDAR 75.566 0.016715 56958000 4971.1 3800.1 4128.2 4652.6 4180.9 3865.5 3025.2 1569.5 4064.3 3887.3 TRUE FALSE FALSE 4577.63219 4128.563711 4281.194724 4633.348774 4131.045498 3063.751727 3110.07897 2048.033325 3618.456458 4022.383386 1.138039752 1.026397366 1.064342782 1.151891386 1.02701436 0.761675711 0.773193073 0.509159155 0.899580202 1 11.97383488 -4.851025936 1.215480506 1.071011231 0.524981132 0.800018677 0.085419579 0.176946415 0.393276271 0.011280362 0.092841973 1.41E-05 4.851025936 -0.546030099 S(ph)RS(ph)PESQVIGENTK ddPTM_HeLa_Curcumin_4h_R1 3 SRSPESQVIGENTK 14 1 O95218-2 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 2 0 S(0.999)RS(0.998)PES(0.002)QVIGENTK;S(0.982)RS(0.993)PES(0.025)QVIGENTK;S(0.999)RS(0.964)PES(0.036)QVIGENTK ;; 156.72 0.0014664 235621000 20349.8 17625.5 18784.8 19592 22138.1 20722.4 19143.1 16854.6 16406.1 15615.4 TRUE FALSE FALSE 18739.09186 19148.96968 19480.98121 19510.9335 21874.11762 16424.34065 19680.20386 21993.48995 14606.39188 16158.03399 1.159738361 1.185105174 1.205652942 1.20750665 1.353761085 1.016481378 1.217982576 1.361148885 0.90397086 1 13.97996405 -9.080760015 0.29441333 0.907358008 1.248086134 0.558165947 0.093549725 2.375314152 0.308810761 0.28546531 0.05798019 8.30E-10 9.080760015 0.340728126 S(ph)RS(ph)PESQVIGENTKQP ddPTM_HeLa_Curcumin_4h_R1 3 SRSPESQVIGENTKQP 16 2 O95218-2 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 2 0 S(0.695)RS(0.877)PES(0.428)QVIGENTKQP;S(0.933)RS(0.933)PES(0.135)QVIGENTKQP;S(0.976)RS(0.791)PES(0.102)QVIGENT(0.132)KQP ;; 107.73 0.0045498 340859600 11194.4 7582.3 8944.3 9961.7 8809.1 10899.7 9322 8230.3 11104.8 10422.7 TRUE FALSE FALSE 10308.35143 8237.680226 9275.783626 9920.481125 8704.057236 8638.979355 9583.550231 10739.68058 9886.631223 10784.88805 0.955814412 0.763816944 0.860072315 0.919850172 0.807060509 0.801026336 0.888609153 0.995808258 0.91671153 1 13.39672358 -7.456014733 8.18510418 0.980646298 0.860698946 0.296072656 0.065441654 0.226529396 25.56251989 0.010779962 0.012248611 3.50E-08 7.456014733 -0.119947351 SQS(ph)PAASDCSSSSSSASLPSSGR ddPTM_HeLa_Curcumin_4h_R1 1 SQSPAASDCSSSSSSASLPSSGR 23 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 0 S(0.003)QS(0.997)PAAS(0.001)DCSSSSSSASLPSSGR 273.37 5.23E-61 16787000 1961.6 1786.7 1603.2 1969.4 1876.3 2203.8 1596.4 531.96 2535.1 1593.9 TRUE FALSE FALSE 1806.33729 1941.134387 1662.616002 1961.251145 1853.926348 1746.707038 1641.190688 694.1521552 2257.005873 1649.287906 1.09522254 1.176953023 1.008081121 1.189150261 1.124076846 1.05906739 0.995090476 0.420879916 1.368472941 1 10.68762755 -4.25136158 3.288204222 1.068843885 0.32360464 0.76554294 0.113265986 0.081113462 1.379594653 0.009751472 0.154686109 5.61E-05 4.25136158 -0.745239245 down S(ph)RS(ph)PSS(ph)PELNNK ddPTM_HeLa_Curcumin_4h_R1 3 SRSPSSPELNNK 12 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 0 S(1)RS(1)PS(0.048)S(0.952)PELNNK;S(1)RS(0.974)PS(0.335)S(0.691)PELNNK;S(1)RS(0.988)PS(0.029)S(0.983)PELNNK ;; 161.87 0.00084749 141141000 25557.2 21581.5 21090.9 23075.5 22543 25795.7 21374.5 17238.1 25532.3 21081.9 TRUE FALSE FALSE 23534.32065 23446.90869 21872.54731 22980.0197 22274.18945 20445.38104 21974.21094 22493.91734 22731.47057 21814.49446 1.078838691 1.074831633 1.002661205 1.053428937 1.021072915 0.937238362 1.007321576 1.031145479 1.042035176 1 14.41299942 -5.513985413 24.40761195 1.039277132 0.991062424 0.317975292 0.032693394 341.3432785 936808.3736 0.005659865 0.011820767 3.06E-06 5.513985413 -0.048214707 S(ph)RS(ph)PT(ph)PPSSAGLGSNSAPPIPDSR ddPTM_HeLa_Curcumin_4h_R1 1 SRSPTPPSSAGLGSNSAPPIPDSR 24 1 J3QK89;Q8IWX8 J3QK89 CHERP Calcium homeostasis endoplasmic reticulum protein 3 0 S(0.966)RS(0.966)PT(0.968)PPS(0.049)S(0.05)AGLGSNSAPPIPDSR 76.421 0.00037989 13935000 3112 2731.6 3256 2981.5 3081 3308.2 2053.6 1728.9 2993.2 2980.2 TRUE FALSE FALSE 2865.681916 2967.707332 3376.670224 2969.163343 3044.261087 2622.042029 2111.218489 2256.033651 2664.853449 3083.761728 0.929281238 0.962365965 1.094984153 0.962838119 0.987190761 0.850273873 0.684624389 0.731584944 0.864156729 1 11.59047558 -4.992960547 2.824468342 0.976274537 0.707050194 0.775421033 0.056545215 0.07455055 1.192507878 0.006970551 0.023825692 1.02E-05 4.992960547 -0.269224343 S(ph)RS(ph)RDS(ph)GDENEPIQER ddPTM_HeLa_Curcumin_4h_R1 2 SRSRDSGDENEPIQER 16 2 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;Q8WX93-4;Q8WX93-7 Q8WX93-3 PALLD Palladin 3 0 S(1)RS(1)RDS(1)GDENEPIQER;S(1)RS(1)RDS(1)GDENEPIQER ; 83.964 0.0073096 33754900 2293.38 1838.82 2142.3 2483.16 2287.17 2763.09 1894.64 1801.35 2611.33 2272.9 TRUE FALSE FALSE 2111.856553 1997.759407 2221.695523 2472.885342 2259.896992 2189.993988 1947.798499 2350.573323 2324.873632 2351.883106 0.897942822 0.84942972 0.944645385 1.051449086 0.960888314 0.931166172 0.828186781 0.999443092 0.98851581 1 11.19960064 -9.473673565 1.261344132 0.999334515 0.928352025 0.130583047 0.062306058 0.71173594 2.055390863 0.042441857 0.010844571 3.36E-10 9.473673565 -0.07098249 S(ph)RS(ph)S(ph)SVGS(ph)SSSYPISPAVSR ddPTM_HeLa_Curcumin_4h_R1 1 SRSSSVGSSSSYPISPAVSR 20 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 4 0 S(0.683)RS(0.733)S(0.734)S(0.674)VGS(0.312)S(0.297)S(0.279)S(0.265)Y(0.018)PIS(0.003)PAVS(0.001)R 44.105 0.019615 2546800 550.87 496.47 558.89 775.99 529.51 578.72 524.78 404.16 522.17 290.33 TRUE FALSE FALSE 507.2680582 539.3826546 579.602955 772.779159 523.1959391 458.6869485 539.5039144 527.3865235 464.8892574 300.4189459 1.688535511 1.795434882 1.929315587 2.572338295 1.741554407 1.526824306 1.795838518 1.755503542 1.547469838 1 8.230831989 -8.616677054 0.661332437 1.007787761 1.881243262 0.327147785 0.303346654 0.388034328 0.338902932 0.169267228 0.066551442 2.42E-09 8.616677054 0.8734555 S(ph)RS(ph)SS(ph)VGSSSSYPISPAVSR ddPTM_HeLa_Curcumin_4h_R1 1 SRSSSVGSSSSYPISPAVSR 20 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 3 0 S(0.692)RS(0.692)S(0.692)S(0.921)VGS(0.002)S(0.001)SSYPISPAVSR 67.928 0.0049387 19104000 544.01 368.54 307 383.76 481.77 563.06 335.11 447.4 585.07 453.84 TRUE FALSE FALSE 500.9510345 400.3949554 318.3776901 382.1721028 476.0252074 446.275009 344.5122847 583.8102004 520.8892848 469.6109062 1.066736372 0.852610001 0.677960596 0.81380585 1.013658757 0.950308017 0.733612189 1.243178539 1.10919333 1 8.875322104 -7.2610796 24.85957631 1.031514399 0.886336432 0.182508388 0.151344222 38.78905128 2680202.963 0.024140176 0.028608349 5.48E-08 7.2610796 -0.145177967 S(ph)RSAPPNLWAAQR ddPTM_HeLa_Curcumin_4h_R1 1 SRSAPPNLWAAQR 13 1 Q92934;F5H3B1;F5H1R6 Q92934 BAD Bcl2-associated agonist of cell death 1 0 S(0.68)RS(0.32)APPNLWAAQR 118.52 0.0011554 5321600 1470.4 960.31 1272 1004.8 1161.6 1452.5 1243.7 1249 1506.3 1493.2 TRUE FALSE FALSE 1354.016288 1043.314917 1319.141439 1000.642404 1147.748679 1151.235127 1278.594875 1629.81435 1341.062659 1545.088589 0.876335699 0.675246018 0.853764275 0.647627852 0.74283681 0.745093282 0.827522049 1.054835536 0.867951953 1 10.59347384 -8.016916418 1.094959212 0.973707959 0.788161963 0.162197388 0.114182269 0.352875975 0.889356373 0.02894186 0.02335058 9.62E-09 8.016916418 -0.185545995 S(ph)RSAVTLPR ddPTM_HeLa_Curcumin_4h_R1 1 SRSAVTLPR 9 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 S(0.754)RS(0.243)AVT(0.003)LPR 78.548 0.015018 5851700 1211 744.29 1025.2 982.82 979.83 1324.1 974.61 834.76 1151.6 1075.9 TRUE FALSE FALSE 1115.148072 808.6231111 1063.194814 978.7533513 968.1461672 1049.466734 1001.954934 1089.274481 1025.272361 1113.287445 1.001671291 0.726338121 0.955004764 0.879156013 0.869628209 0.942673646 0.899996616 0.978430581 0.920941277 1 10.12061042 -7.420576035 24.6452582 1.000806661 0.893862185 0.194269379 0.069684161 23.62506344 5685.013375 0.010227095 0.011695102 3.80E-08 7.420576035 -0.106944476 S(ph)RSDIDVNAAASAK ddPTM_HeLa_Curcumin_4h_R1 2 SRSDIDVNAAASAK 14 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 0 S(0.769)RS(0.231)DIDVNAAASAK;S(0.5)RS(0.5)DIDVNAAASAK ; 152.01 0.00020214 551780000 18827.7 14282 16611.8 16444.1 16581.2 18206.9 14441.4 11320.6 18624.5 15780.6 TRUE FALSE FALSE 17337.46768 15516.47244 17227.44792 16376.05867 16383.48002 14430.58371 14846.58682 14772.19883 16581.43895 16328.97468 1.061760951 0.950241687 1.055023249 1.002883463 1.003337953 0.883740957 0.909217334 0.904661751 1.015461122 1 13.99514658 -5.346745754 4.067177077 1.023116427 0.899991295 0.739115602 0.030585543 0.087525179 2.665218373 0.004838836 0.011436984 4.50E-06 5.346745754 -0.123125131 S(ph)RSESDLSQPESDEEGYALSGR ddPTM_HeLa_Curcumin_4h_R1 1 SRSESDLSQPESDEEGYALSGR 22 1 Q15751;H0YNB1 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 0 S(0.331)RS(0.331)ES(0.331)DLS(0.006)QPESDEEGYALSGR 130.81 7.17E-06 14798000 2282.3 2261.9 2510.7 2535 2878.2 3084.6 2000.2 3745.6 2866.4 2610.2 TRUE FALSE FALSE 2101.653547 2457.408557 2603.748751 2524.510842 2843.879345 2444.819189 2056.320229 4887.616197 2551.963091 2700.904256 0.778129599 0.909846601 0.964028527 0.934690979 1.052936008 0.905185433 0.761345103 1.809622162 0.944855074 1 11.39922678 -4.255819887 24.94859297 0.905951969 1.809622559 0.907033419 0.085689629 148.0389739 657221.2803 0.014207712 0.166637433 5.55E-05 4.255819887 0.90367059 MGVMS(ph)SPTENSFTLDADF ddPTM_HeLa_Curcumin_4h_R1 1 MGVMSSPTENSFTLDADF 18 0 P31350-2;P31350 P31350-2 RRM2 Ribonucleoside-diphosphate reductase subunit M2 1 0 MGVMS(0.504)S(0.416)PT(0.063)ENS(0.014)FT(0.002)LDADF 51.841 0.019538 2880700 574.53 493.19 293.56 508.84 357.73 911.36 924.33 1505.3 800.57 590.44 TRUE FALSE FALSE 529.0553443 535.819146 304.4395918 506.7345549 353.4643034 722.3336629 950.2642121 1964.25904 712.7494739 610.9577461 0.865944245 0.877015063 0.498298931 0.829410149 0.578541324 1.18229725 1.555368138 3.215048918 1.166610095 1 9.254928796 -4.154504917 1.547212363 0.870563671 4.56527255 0.930857451 0.194202627 0.238908402 0.431403176 0.026809045 1.439457601 7.01E-05 4.154504917 3.694708879 up S(ph)RSFEVT(ph)GQGLSHPK ddPTM_HeLa_Curcumin_4h_R1 1 SRSFEVTGQGLSHPK 15 1 Q2TAC6 Q2TAC6 KIF19 Kinesin-like protein KIF19 2 0 S(0.963)RS(0.037)FEVT(0.854)GQGLS(0.146)HPK 81.651 0.0084628 0 1491.9 1584.5 1521.7 1740.7 1690.1 2247.8 1730.6 1355.5 1708.9 1576.7 TRUE FALSE FALSE 1373.814541 1721.45712 1578.095541 1733.497445 1669.946661 1781.580942 1779.155978 1768.78571 1521.437945 1631.490208 0.842061162 1.05514401 0.967272456 1.062523965 1.023571367 1.091996099 1.09050975 1.084153433 0.932544945 1 10.67197461 -6.488043846 1.189290251 0.929360268 1.077682189 0.543006534 0.052173767 0.29542081 0.833063382 0.012184752 0.021343753 3.25E-07 6.488043846 0.148321921 S(ph)RSLGPGAGPR ddPTM_HeLa_Curcumin_4h_R1 3 SRSLGPGAGPR 11 1 H3BUV2;P78549-3;P78549-2;P78549 H3BUV2 NTHL1 Endonuclease III-like protein 1 1 0 S(0.98)RS(0.02)LGPGAGPR;S(0.865)RS(0.135)LGPGAGPR;S(0.982)RS(0.018)LGPGAGPR ;; 91.307 0.0071673 42538600 3329.55 2945.66 2992.61 3146.31 2854.05 3460.79 2420.38 3307.38 3526.94 2764.12 TRUE FALSE FALSE 3066.012604 3200.269725 3103.518759 3133.291403 2820.017318 2742.983143 2488.289349 4315.784937 3140.043506 2860.172964 1.07196755 1.11890776 1.085080797 1.095490183 0.985960413 0.959027016 0.869978627 1.508924457 1.097850915 1 11.48188668 -4.249196794 24.96208275 1.031386942 1.508924756 0.78835353 0.074198201 660.4794741 1346664.2 0.010373428 0.239395315 5.63E-05 4.249196794 0.477537814 S(ph)RSPAYSR ddPTM_HeLa_Curcumin_4h_R1 1 SRSPAYSR 8 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 1 0 S(0.999)RS(0.001)PAYSR 73.26 0.017469 5177400 998.62 1180.9 851.24 702.25 719.75 788.67 839.25 1596.8 650.22 850.79 TRUE FALSE FALSE 919.5781733 1282.971734 882.7877032 699.3442756 711.1674513 625.0909519 862.7970963 2083.656969 578.8924928 880.3548892 1.044553946 1.457334706 1.002763447 0.79438904 0.807819051 0.710044278 0.980056006 2.366837505 0.657567192 1 9.781941411 -4.261003546 24.9365154 0.997192339 2.366837934 0.786687708 0.221155461 10.9499661 626296.1978 0.027900095 0.219812025 5.48E-05 4.261003546 1.369645594 S(ph)RSPES(ph)QVIGENTK ddPTM_HeLa_Curcumin_4h_R1 1 SRSPESQVIGENTK 14 1 O95218-2 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 2 0 S(0.815)RS(0.539)PES(0.644)QVIGENT(0.002)K 121.45 0.0066639 34007000 6882.7 6361.9 6412.2 6923.1 7876 7430.4 6880.5 5745.4 5838.4 5458.2 TRUE FALSE FALSE 6337.927032 6911.794288 6649.841773 6894.454047 7782.083844 5889.251282 7073.548312 7497.146011 5197.942127 5647.872044 1.122179643 1.223787337 1.177406592 1.220717111 1.377878922 1.042738086 1.252427154 1.327428446 0.920336383 1 12.46349169 -7.853781875 0.489230793 0.999003839 1.249991499 0.588637411 0.088384915 0.466302103 0.274568821 0.045279503 0.03142023 1.40E-08 7.853781875 0.25098766 S(ph)RSPGSPVGEGTGSPPK ddPTM_HeLa_Curcumin_4h_R1 2 SRSPGSPVGEGTGSPPK 17 1 E7EV99;E7ENY0;P35611-5;P35611-2;P35611-6;P35611-4;P35611;P35611-3;A0A0A0MSR2;H0Y9H2 E7EV99 ADD1 Alpha-adducin 1 0 S(0.81)RS(0.145)PGS(0.044)PVGEGTGS(0.001)PPK;S(0.622)RS(0.311)PGS(0.065)PVGEGT(0.001)GS(0.002)PPK ; 77.221 0.0050495 89222000 10136.6 7457.9 9101.9 9684.7 9311.3 12212.2 10080.5 12915.6 10539.8 8405.4 TRUE FALSE FALSE 9334.277414 8102.527644 9439.224421 9644.627278 9200.268829 9679.25206 10363.3317 16853.50698 9383.610309 8697.487024 1.073215446 0.931594105 1.085281805 1.108898151 1.05780771 1.112879161 1.191531723 1.937744424 1.078887532 1 13.08638291 -4.026942161 1.690908398 1.039826893 2.757954402 0.960424395 0.053327122 0.251125076 0.423206911 0.007800121 0.841548634 9.40E-05 4.026942161 1.718127508 STS(ph)QGSINSPVYSR ddPTM_HeLa_Curcumin_4h_R1 1 STSQGSINSPVYSR 14 0 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4;A0A494C1P1;A0A494C1G0;H0Y7N6;F6XFR5 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 ST(0.002)S(0.997)QGS(0.001)INSPVYSR 177.63 0.00016667 92398000 1849.2 1015.5 1581 1544.1 1091.9 3015 3059.1 7120 1870.7 2034.2 TRUE FALSE FALSE 1702.833869 1103.275295 1639.593251 1537.710923 1078.879806 2389.655014 3144.930113 9290.855224 1665.48889 2104.888299 0.808990135 0.524149094 0.778945492 0.730542768 0.512559173 1.135288279 1.494107842 4.41394217 0.791248111 1 11.03952796 -4.154455025 1.973973471 0.837057875 6.207722344 0.973096496 0.180451281 0.131708557 0.426509765 0.028588597 1.402059894 7.01E-05 4.154455025 5.370664469 up S(ph)RSPSSPELNNK ddPTM_HeLa_Curcumin_4h_R1 1 SRSPSSPELNNK 12 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.676)RS(0.32)PS(0.004)SPELNNK 79.036 0.011188 7043600 2953.5 3153.3 2620.3 2926.3 2987.6 2836.6 2350.7 1533 3074.3 2943.1 TRUE FALSE FALSE 2719.727358 3425.857201 2717.410623 2914.191746 2951.974821 2248.257185 2416.654315 2000.404643 2737.056982 3045.372506 0.893068862 1.124938639 0.892308122 0.95692456 0.969331277 0.73825359 0.79354966 0.656866981 0.898759339 1 11.57240299 -5.259440892 24.14569312 0.959229207 0.735956011 0.688567146 0.071637174 48.06426843 580700.5878 0.009988538 0.024123805 5.50E-06 5.259440892 -0.223273196 S(ph)RSQPCDLDAR ddPTM_HeLa_Curcumin_4h_R1 2 SRSQPCDLDAR 11 1 Q9NYF3 Q9NYF3 FAM53C Protein FAM53C 1 0 S(0.733)RS(0.267)QPCDLDAR;S(0.922)RS(0.078)QPCDLDAR ; 130.01 0.0012433 73356000 9122.9 8782.7 8278.2 8378.7 8434.9 9845.5 6665.9 6367 10327.9 9032.7 TRUE FALSE FALSE 8400.812839 9541.837453 8584.997374 8344.031159 8334.319327 7803.432318 6852.927214 8308.26899 9194.955209 9346.585653 0.898810876 1.020890174 0.918516953 0.892735751 0.891696673 0.834896572 0.733201136 0.888909523 0.983776916 1 13.19022372 -5.689270301 1.085714924 0.955953196 0.80609884 0.605994503 0.05016876 0.295733773 0.670829266 0.008911308 0.028124008 2.05E-06 5.689270301 -0.149854356 LVPS(ph)QEETKLSVEESEAAGDGVDTK ddPTM_HeLa_Curcumin_4h_R1 2 LVPSQEETKLSVEESEAAGDGVDTK 25 1 P49321-4;P49321;P49321-3 P49321-4 NASP Nuclear autoantigenic sperm protein 1 0 LVPS(0.495)QEET(0.495)KLS(0.011)VEESEAAGDGVDTK;LVPS(0.442)QEET(0.442)KLS(0.109)VEES(0.007)EAAGDGVDTK ; 88.222 2.22E-05 196446000 5001.2 4580.7 4855 4967.1 4628.6 6306.2 5681.4 7200.7 5698.2 4518.1 TRUE FALSE FALSE 4605.349743 4976.635297 5034.930571 4946.547456 4573.406968 4998.223034 5840.804793 9396.160282 5073.121716 4675.103639 0.985079711 1.064497321 1.076966621 1.058061562 0.978247184 1.069114916 1.249342313 2.009829302 1.085135669 1 12.19078263 -4.152667383 1.771959418 1.009211748 2.552228157 0.977419167 0.044058313 0.111381922 0.276460184 0.006060497 0.313320856 7.04E-05 4.152667383 1.543016409 up S(ph)RSTTELDDYSTNK ddPTM_HeLa_Curcumin_4h_R1 1 SRSTTELDDYSTNK 14 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 S(0.97)RS(0.022)T(0.008)TELDDYSTNK 170.35 0.0019361 153880000 5532.4 4954.5 5627.4 5504.2 5330.5 5388 4891.8 6879 5467.6 4946.4 TRUE FALSE FALSE 5094.504702 5382.744903 5835.956394 5481.425079 5266.937269 4270.468065 5029.050742 8976.375433 4867.817959 5118.287032 0.995353459 1.051669215 1.140216709 1.070949137 1.029042966 0.834354939 0.982565204 1.75378508 0.951063887 1 12.32144534 -4.260342795 24.99550269 1.006149823 1.753785319 0.89658435 0.076175823 20.64745778 470575.2299 0.010609 0.087021306 5.49E-05 4.260342795 0.747635496 SKDYDVYS(ph)DNDICSQESEDNFAK ddPTM_HeLa_Curcumin_4h_R1 1 SKDYDVYSDNDICSQESEDNFAK 23 1 A0A0C4DGZ1;Q8N5P1 A0A0C4DGZ1 ZC3H8 Zinc finger CCCH domain-containing protein 8 1 0 S(0.001)KDY(0.002)DVY(0.104)S(0.844)DNDICS(0.048)QES(0.001)EDNFAK 89.511 9.56E-05 54060000 3490.3 2985.1 3131 3642.1 3198.7 3766.5 2265.7 823.6 3597.7 3321.6 TRUE FALSE FALSE 3214.039072 3243.118743 3247.037614 3627.029955 3160.557592 2985.285443 2329.269444 1074.711849 3203.041311 3437.025353 0.935122306 0.943583014 0.944723207 1.055281699 0.919561908 0.868566605 0.677699233 0.312686622 0.931922515 1 11.74694478 -4.251098202 1.236300595 0.969666206 6.51E-22 0.966346769 0.037555834 0.18584214 0.230858659 0.005830525 0.230774031 5.61E-05 4.251098202 -0.969666206 down S(ph)RT(ph)PPSAPSQSR ddPTM_HeLa_Curcumin_4h_R1 1 SRTPPSAPSQSR 12 1 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(1)RT(1)PPSAPSQSR 105.14 0.010949 293330000 1364.5 1730.1 1258.6 1414.2 1153.4 1218.6 1120 598.06 1509.5 1385.7 TRUE FALSE FALSE 1256.498385 1879.642135 1305.244823 1408.348415 1139.646458 965.8486235 1151.424186 780.4057409 1343.911627 1433.852972 0.876309085 1.310902981 0.910305902 0.982212572 0.79481403 0.67360367 0.803028071 0.544271802 0.937272965 1 10.48568138 -5.586896877 2.595714284 0.971722224 0.68576661 0.569270076 0.128461297 0.179628333 2.439052687 0.019267895 0.043920597 2.59E-06 5.586896877 -0.285955614 LEPTNVQTVTCS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 LEPTNVQTVTCSPR 14 0 J3KTI7;J3QR52;J3QLN7;Q99741 J3KTI7 CDC6 Cell division control protein 6 homolog 1 0 LEPTNVQTVT(0.002)CS(0.998)PR 165.24 0.0002163 102600000 3634.5 3387.5 3278.2 3695.5 3062.4 3330.8 2420.7 754.67 3451.2 3021.8 TRUE FALSE FALSE 3346.82549 3680.300406 3399.692976 3680.209 3025.88288 2639.954534 2488.618327 984.7654089 3072.611994 3126.807325 1.070365117 1.17701541 1.087272934 1.176986177 0.967722845 0.844297157 0.795897562 0.314942786 0.982667518 1 11.61047461 -4.249665963 1.100495202 1.056385616 3.41E-15 0.893597485 0.078409041 0.414970713 0.390387679 0.012281803 0.511202718 5.63E-05 4.249665963 -1.056385616 down S(ph)RTGSESS(ph)QTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 0 S(0.656)RT(0.121)GS(0.132)ES(0.135)S(0.288)QT(0.206)GT(0.082)S(0.174)T(0.106)T(0.02)S(0.067)S(0.013)R 88.396 0.013691 3266600 1586.7 1621.1 1749.5 1424.2 1234.6 1748.4 938.06 736.4 2073.7 1739.8 TRUE FALSE FALSE 1461.111021 1761.220661 1814.338009 1418.307038 1219.878201 1385.762131 964.3794389 960.92497 1846.220298 1800.257921 0.81161205 0.97831574 1.007821151 0.787835466 0.677613017 0.769757553 0.535689596 0.533770722 1.025530996 1 10.8139879 -5.053512698 0.659758135 0.925254564 0.437133523 0.77849976 0.084338476 0.603675488 0.317913676 0.01742976 0.181748548 8.84E-06 5.053512698 -0.488121042 SSSSSGVPYS(ph)PAIPNKR ddPTM_HeLa_Curcumin_4h_R1 2 SSSSSGVPYSPAIPNKR 17 1 A0A0A0MRE1;B4DJ07;A0A0A0MSB8;Q9UPT5-4;Q9UPT5-2;Q9UPT5-5;Q9UPT5-1;Q9UPT5-6;Q9UPT5 A0A0A0MRE1 EXOC7 Exocyst complex component 7 1 0 SSSSSGVPYS(1)PAIPNKR;SSSS(0.002)S(0.011)GVPYS(0.987)PAIPNKR ; 134.83 0.0001638 214405000 6462.9 4860.1 5072.7 5372 5395.4 6907.4 5026.6 1577.87 6117.8 5209.3 TRUE FALSE FALSE 5951.354645 5280.185388 5260.698724 5349.772087 5331.063379 5474.727378 5167.632868 2058.955299 5446.692646 5390.322787 1.10408131 0.979567569 0.975952449 0.99247713 0.989006334 1.015658541 0.95868709 0.381972542 1.010457604 1 12.39615595 -4.249173966 3.28719249 1.029310135 0.282937829 0.957353538 0.039234898 0.062586993 1.0587014 0.007415129 0.119805536 5.63E-05 4.249173966 -0.746372305 down SCS(ph)IDRSPGAGSLGSPASQR ddPTM_HeLa_Curcumin_4h_R1 1 SCSIDRSPGAGSLGSPASQR 20 1 E9PC47;P53667-4;P53667-2;P53667 E9PC47 LIMK1 LIM domain kinase 1 1 0 S(0.013)CS(0.987)IDRSPGAGSLGSPASQR 111.63 0.001189 0 436.88 399.98 420.96 479.4 338.01 759.4 842.16 2003.4 405.92 479.7 TRUE FALSE FALSE 402.300487 434.5524889 436.5611479 477.4163698 333.9794515 601.8918798 865.788743 2614.227437 361.3915916 496.3695393 0.810485848 0.875461636 0.879508337 0.961816413 0.672844373 1.212588268 1.744242292 5.26669594 0.72806964 1 8.955270774 -4.150505618 1.92854088 0.899651756 7.532681399 0.989238275 0.136559315 0.07245667 0.219614861 0.018511637 0.938778476 7.07E-05 4.150505618 6.633029644 up S(ph)RTPLLPR ddPTM_HeLa_Curcumin_4h_R1 2 SRTPLLPR 8 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.681)RT(0.319)PLLPR;S(1)RTPLLPR ; 103.88 0.0036785 5536000 1378.08 1395.07 1393.48 1498.56 1503.75 1580 1111.33 1108.08 1295.18 1229.74 TRUE FALSE FALSE 1269.003514 1515.653634 1445.123595 1492.359356 1485.818763 1252.29019 1142.510929 1445.928491 1153.101994 1272.473373 0.997273138 1.19110833 1.135680812 1.17280203 1.167661968 0.98413862 0.897866276 1.136313357 0.906189488 1 10.31341975 -7.390849432 22.01419743 0.998706042 1.092982295 0.279676353 0.091519562 7.562609542 1274.89299 0.015814038 0.018083909 4.07E-08 7.390849432 0.094276253 S(ph)RTPPSAPSQSR ddPTM_HeLa_Curcumin_4h_R1 5 SRTPPSAPSQSR 12 1 Q9UQ35;I3L3Q8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.969)RT(0.031)PPSAPSQSR;S(0.995)RT(0.005)PPSAPSQSR;S(0.741)RT(0.137)PPSAPS(0.001)QS(0.121)R;S(0.5)RT(0.5)PPSAPSQSR;S(0.499)RT(0.499)PPSAPSQS(0.001)R ;;;; 105.36 0.0030424 1202156000 10012.6 9022.5 8796.9 9004.97 9007.15 11180 9581.4 12439.2 10032.5 8457.9 TRUE FALSE FALSE 9220.092145 9802.364697 9122.920853 8967.70982 8899.745619 8861.141975 9850.228297 16231.85482 8931.95985 8751.811395 1.053506723 1.120038384 1.042403731 1.024668999 1.016903269 1.012492337 1.125507378 1.854685171 1.020584134 1 13.09536593 -4.258288558 3.504279912 1.032916248 1.957175057 0.983133493 0.031951789 0.029274277 0.617973723 0.005151865 0.071621081 5.52E-05 4.258288558 0.924258809 S(ph)RTSVQTEDDQLIAGQSAR ddPTM_HeLa_Curcumin_4h_R1 1 SRTSVQTEDDQLIAGQSAR 19 1 G3XAM7;P35221-3;P35221;P35221-2;A0A0A0MTJ6;A0A0A0MRI5;P26232-4;P26232-6;P26232-3;P26232-2;P26232-5;P26232 G3XAM7 CTNNA1;CTNNA2 Catenin alpha-1;Catenin alpha-2 1 0 S(0.58)RT(0.344)S(0.076)VQTEDDQLIAGQSAR 135.76 8.42E-05 69844000 1645.9 1253.1 1335.5 1572.9 1238 2082.5 1298.7 657.76 1702.5 1191.8 TRUE FALSE FALSE 1515.625278 1361.41238 1384.994805 1566.391757 1223.237659 1650.566025 1335.138027 858.307996 1515.740009 1233.214961 1.229003317 1.10395383 1.123076551 1.270169278 0.991909519 1.338425236 1.082648256 0.695992202 1.229096351 1 10.26820858 -4.273441298 4.710149332 1.129090704 0.674374697 0.605019497 0.109660086 0.096647516 5.812351259 0.01586598 0.140960198 5.33E-05 4.273441298 -0.454716007 S(ph)RVFDLQFSTDSPR ddPTM_HeLa_Curcumin_4h_R1 1 SRVFDLQFSTDSPR 14 1 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 0 S(1)RVFDLQFSTDSPR 101.28 0.0020749 7880700 1248 1171.1 1024.5 1048.5 1062.2 1896.4 902.23 1061.9 1090.8 882.54 TRUE FALSE FALSE 1149.219483 1272.324666 1062.468871 1044.161585 1049.533959 1503.065263 927.5441456 1385.668422 971.141969 913.2081993 1.258441924 1.393247089 1.163446487 1.143399266 1.149282233 1.645917398 1.015698442 1.517363097 1.063439827 1 9.834800003 -12.92058831 0.192291739 4.14E-13 1.339262361 0.248687971 0.179275885 39.94316519 0.584170495 15.10461977 0.198265917 1.20E-13 12.92058831 1.339262361 S(ph)S(ph)S(ph)ERSTPPYLFPEY(ph)PEAS(ph)KNTGQNR ddPTM_HeLa_Curcumin_4h_R1 1 SSSERSTPPYLFPEYPEASKNTGQNR 26 2 Q8TE76-2;Q8TE76-3;Q8TE76 Q8TE76-2 MORC4 MORC family CW-type zinc finger protein 4 5 0 S(0.878)S(0.878)S(0.878)ERS(0.228)T(0.225)PPY(0.212)LFPEY(0.723)PEAS(0.835)KNT(0.141)GQNR 41.76 0.0077853 0 970.45 919.28 863.67 807.54 883.61 1238.2 938.52 669.11 788.76 991.46 TRUE FALSE FALSE 893.6378585 998.738467 895.67837 804.1986135 873.0735279 981.3833626 964.8523453 873.1185588 702.2350014 1025.913161 0.87106579 0.973511701 0.873054761 0.783885658 0.851020886 0.956594963 0.940481497 0.85106478 0.684497507 1 10.0026929 -9.413278939 0.680561678 1.017530772 0.886335223 0 0.112696784 0.957039613 0.618363823 0.07708773 0.011861355 3.86E-10 9.413278939 -0.131195549 S(ph)S(ph)S(ph)PVNVK ddPTM_HeLa_Curcumin_4h_R1 1 SSSPVNVK 8 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1X7SBS1 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 3 0 S(1)S(1)S(1)PVNVK 66.962 0.016966 2666500 3119.4 1482.9 2202.7 2789.2 3101.4 38.982 686.08 756.5 2010.3 2137.9 TRUE FALSE FALSE 2872.496198 1611.075268 2284.334 2777.659029 3064.417831 30.89669378 705.3295583 987.1533675 1789.77512 2212.191866 1.298484206 0.728271039 1.032611156 1.255613978 1.385240529 0.013966552 0.318837425 0.44623316 0.809050583 1 11.1112608 -5.261165185 24.99996332 1.126815811 0.265594863 0.733710991 0.22279897 8.370204102 763109.6835 0.030226782 0.072113094 5.48E-06 5.261165185 -0.861220948 S(ph)S(ph)S(ph)VRRT(ph)QAIRR ddPTM_HeLa_Curcumin_4h_R1 1 SSSVRRTQAIRR 12 3 Q9H6A9-2;Q9H6A9 Q9H6A9-2 PCNXL3 Pecanex-like protein 3 4 0 S(1)S(1)S(1)VRRT(1)QAIRR 51.135 0.0090363 0 349.85 407.88 541.42 1355.4 2427.9 9319.5 9603.7 53183 0 0 TRUE FALSE FALSE 322.1590033 443.1353297 561.4855015 1349.791714 2398.948878 7386.530648 9873.153975 69398.25188 0 0 0 S(ph)S(ph)SPVT(ph)ELASRSPIR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPVTELASRSPIR 15 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 0 S(0.981)S(0.819)S(0.2)PVT(0.999)ELASRSPIR 103.66 0.0046421 10424000 2041.2 1496.3 1665.9 1763.2 1729.8 2102.5 1271 1408.7 1602 1706.8 TRUE FALSE FALSE 1879.636866 1625.633505 1727.639719 1755.904346 1709.173265 1666.4178 1306.660839 1838.206145 1426.264608 1766.111173 1.064280038 0.920459329 0.978216856 0.994220733 0.967760858 0.94355204 0.739851975 1.04082131 0.807573515 1 10.78636045 -5.832323496 0.729635437 1.025219908 0.888852412 0 0.104000128 0.725483516 0.695658407 0.01440691 0.053058677 1.47E-06 5.832323496 -0.136367496 S(ph)SASFSTTAVSAR ddPTM_HeLa_Curcumin_4h_R1 1 SSASFSTTAVSAR 13 0 A0A096LP52;A0A1B0GWF2;A0A1B0GVQ5;A0A2R8Y5D4;A0A0D9SG72;A0A1B0GTP9;P61764;P61764-2 A0A096LP52 STXBP1 Syntaxin-binding protein 1 1 0 S(0.972)S(0.018)AS(0.01)FSTTAVSAR 113.54 0.0032909 4175000 619.3 680.36 514.98 540.18 777.46 936.41 943.5 632.67 903.01 777.45 TRUE FALSE FALSE 570.2817515 739.1672868 534.0656118 537.9448783 768.1892973 742.1880105 969.9720707 825.5681705 803.9520622 804.4663296 0.708894494 0.918829365 0.663875655 0.668697817 0.954905468 0.922584306 1.205733584 1.026230857 0.999360735 1 9.651888229 -5.046274229 2.242523797 0.837695619 1.113559152 0.39490104 0.129805507 0.258907974 2.518039088 0.020959659 0.075920995 8.99E-06 5.046274229 0.275863533 S(ph)SCSSEPNTPK ddPTM_HeLa_Curcumin_4h_R1 1 SSCSSEPNTPK 11 0 I3L2J0;A0A0A0MQR4;Q96RK0;I3L373;I3L135;I3L1Q4 I3L2J0 CIC Protein capicua homolog 1 0 S(0.82)S(0.177)CS(0.003)S(0.001)EPNTPK 89.44 0.01805 6241000 2740.7 2498.7 2734.7 2762.7 2483.1 2192.1 1444.1 1583.9 2588.4 2514.4 TRUE FALSE FALSE 2523.770703 2714.676494 2836.050388 2751.268679 2453.490654 1737.43375 1484.617559 2066.823819 2304.458996 2601.775213 0.970018736 1.043393941 1.090044357 1.057458256 0.943006391 0.667787802 0.570617151 0.794389849 0.885725632 1 11.34528061 -5.313880201 3.988179849 1.003130277 0.664116821 0.803902864 0.073025964 0.058900951 1.95232148 0.009122514 0.022036704 4.85E-06 5.313880201 -0.339013456 S(ph)SDEDAAGEPK ddPTM_HeLa_Curcumin_4h_R1 2 SSDEDAAGEPK 11 0 E9PHH9;Q9BUI4 E9PHH9 POLR3C DNA-directed RNA polymerase III subunit RPC3 1 0 S(0.99)S(0.01)DEDAAGEPK;S(0.99)S(0.01)DEDAAGEPK ; 232.78 8.11E-17 147203000 8287.5 6273.5 8273.2 7840 8372.3 11703.9 10925.4 7923.2 7893.4 7370 TRUE FALSE FALSE 7631.53563 6815.753386 8579.81207 7807.560157 8272.465791 9276.37921 11231.93732 10338.94721 7027.513768 7626.106951 1.000711855 0.893739549 1.125057926 1.023793688 1.084756068 1.216397733 1.472827144 1.355730686 0.921507371 1 12.89673105 -5.114321964 1.63258662 1.002654227 1.426762459 0.852821406 0.068410637 0.091171832 0.449447733 0.008670312 0.036008085 7.69E-06 5.114321964 0.424108232 IQAAAS(ph)TPTNATAASDANTGDR ddPTM_HeLa_Curcumin_4h_R1 2 IQAAASTPTNATAASDANTGDR 22 0 P49841;P49841-2 P49841 GSK3B Glycogen synthase kinase-3 beta 1 0 IQAAAS(0.483)T(0.483)PT(0.032)NAT(0.002)AASDANTGDR;IQAAAS(0.656)T(0.33)PT(0.013)NATAASDANTGDR ; 191.44 5.34E-13 23387000 4516.9 4117.3 4794.6 4831.6 5010.1 7562.2 8273.1 21397.4 3183.7 4371.5 TRUE FALSE FALSE 4159.382599 4473.181066 4972.292094 4811.608119 4950.35783 5993.714476 8505.22092 27921.36876 2834.456075 4523.4093 0.91952382 0.988895934 1.099235502 1.063712744 1.094386447 1.325043585 1.880267815 6.172638138 0.626619412 1 12.14319483 -4.148146987 2.015284742 1.000996977 8.811368616 0.988263718 0.167824377 0.059948225 0.201141661 0.018727711 0.948634776 7.11E-05 4.148146987 7.810371639 up S(ph)SDELDAWTDFR ddPTM_HeLa_Curcumin_4h_R1 2 SSDELDAWTDFR 12 0 O43524;O43524-2 O43524 FOXO3 Forkhead box protein O3 1 0 S(0.854)S(0.146)DELDAWTDFR;S(0.999)S(0.001)DELDAWTDFR ; 237.07 2.45E-20 29531000 2583.9 2000.06 2006.57 1985.12 2005.1 2546.2 1434.2 1226.98 2277.28 2168 TRUE FALSE FALSE 2379.381588 2172.936274 2080.935249 1976.906099 1981.190492 2018.089418 1474.439792 1601.080554 2027.468081 2243.337839 1.060643452 0.968617493 0.927606718 0.881234233 0.883144062 0.899592288 0.657252674 0.713704608 0.903772961 1 11.13143119 -4.852874321 0.485444241 1.029884045 0.545123043 0.700343128 0.063478027 0.756494306 0.171356134 0.012318017 0.188151946 1.40E-05 4.852874321 -0.484761002 S(ph)SDGGSEEPPDRR ddPTM_HeLa_Curcumin_4h_R1 2 SSDGGSEEPPDRR 13 1 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4 Q9HCD6 TANC2 Protein TANC2 1 0 S(0.497)S(0.497)DGGS(0.006)EEPPDRR;S(0.484)S(0.484)DGGS(0.033)EEPPDRR ; 104.9 0.0024089 11135300 887.27 903.26 817.66 957.8 1039.3 1428.67 1083.55 864.29 1025.1 1068.74 TRUE FALSE FALSE 817.0416433 981.3337696 847.9631989 953.8368774 1026.907026 1132.347738 1113.951497 1127.808042 912.6490947 1105.878635 0.738816735 0.887379264 0.766777811 0.862514969 0.928589262 1.023934907 1.007299952 1.019829849 0.825270573 1 10.11097735 -5.469936557 2.856102454 0.864819896 1.01636114 0.549522502 0.067971893 0.25661828 4.122974395 0.014868229 0.035502775 3.39E-06 5.469936557 0.151541245 ASVSPMDEPVPDSES(ph)PIEK ddPTM_HeLa_Curcumin_4h_R1 8 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 ASVSPMDEPVPDS(0.306)ES(0.693)PIEK;ASVSPMDEPVPDS(0.412)ES(0.588)PIEK;ASVSPMDEPVPDS(0.013)ES(0.987)PIEK;ASVSPMDEPVPDS(0.003)ES(0.997)PIEK;ASVSPMDEPVPDS(0.069)ES(0.931)PIEK;ASVSPMDEPVPDS(0.414)ES(0.586)PIEK;ASVSPMDEPVPDS(0.378)ES(0.622)PIEK;ASVSPMDEPVPDS(0.005)ES(0.995)PIEK ;;;;;;; 226.23 9.08E-25 514380500 33219.6 27637.2 29943 31189.3 31856.4 38868.5 36776.9 46880.8 31523.1 27107.1 TRUE FALSE FALSE 30590.23361 30026.03642 31052.71392 31060.24694 31476.53324 30806.73496 37808.76083 61174.54011 28065.0948 28049.06971 1.090597083 1.070482434 1.107085342 1.107353907 1.122195266 1.098315747 1.347950618 2.180982854 1.000571323 1 14.7756653 -4.145314517 1.711362666 1.060159275 2.821349387 0.984658295 0.041540138 0.124404449 0.27981914 0.007173146 0.390716792 7.16E-05 4.145314517 1.761190112 up S(ph)SEDIIK ddPTM_HeLa_Curcumin_4h_R1 2 SSEDIIK 7 0 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 S(0.992)S(0.008)EDIIK;S(0.992)S(0.008)EDIIK ; 113.71 0.014982 52187000 7229.8 6978.3 6090 6114.9 7930.4 10629 9642.1 7129.9 9173 7030.8 TRUE FALSE FALSE 6657.553701 7581.473157 6315.700757 6089.598164 7835.83516 8424.425586 9912.631376 9303.773688 8166.74485 7275.119777 0.91511259 1.042109737 0.868123268 0.837044386 1.07707301 1.157977579 1.362538581 1.27884818 1.12255813 1 12.82875529 -5.175827491 1.973830417 0.951492992 1.318797393 0.717253679 0.086444831 0.100849237 0.748207018 0.010184021 0.034847662 6.67E-06 5.175827491 0.367304401 S(ph)SEDLAGPLPSSVSSSSTTSSKPK ddPTM_HeLa_Curcumin_4h_R1 3 SSEDLAGPLPSSVSSSSTTSSKPK 24 1 Q9NRF2-3;Q9NRF2-2;Q9NRF2 Q9NRF2-3 SH2B1 SH2B adapter protein 1 1 0 S(0.787)S(0.212)EDLAGPLPSSVSSSSTTSSKPK;S(0.765)S(0.234)EDLAGPLPSSVSSSSTTSSKPK;S(0.817)S(0.183)EDLAGPLPSSVSSSSTTSSKPK ;; 143.37 4.29E-08 69184000 6253.8 4731.66 5701.1 5101.86 6374.6 6080.4 4987 2210.03 5584.5 5197.3 TRUE FALSE FALSE 5758.805131 5140.643607 5912.387781 5080.749855 6298.587058 4819.2565 5126.921798 2883.857973 4971.894322 5377.905788 1.070826704 0.955882049 1.099384782 0.944745047 1.171196988 0.896121407 0.953330534 0.536241817 0.924503797 1 12.39282877 -3.96842955 1.449247627 1.031857549 2.81E-12 0.743407485 0.082131718 0.724691637 0.787554514 0.009644357 1.321005225 0.00010754 3.96842955 -1.031857549 S(ph)SEHINEGETAMLVCK ddPTM_HeLa_Curcumin_4h_R1 1 SSEHINEGETAMLVCK 16 0 A0A087WUV8;P35613-3;P35613-4;P35613-2;P35613;R4GN83;R4GMX5;I3L192;A0A087X2B5 A0A087WUV8 BSG Basigin 1 0 S(0.452)S(0.452)EHINEGET(0.096)AMLVCK 102.9 0.0021645 20879000 738.56 580.83 589.49 620.54 794.61 749.47 454.82 742.19 650.61 564.56 TRUE FALSE FALSE 680.1021967 631.0343571 611.337018 617.9723699 785.1347947 594.0214737 467.5810251 968.4803144 579.2397107 584.178418 1.16420288 1.080208268 1.046490249 1.057848683 1.34399829 1.0168494 0.800407907 1.657850212 0.991545892 1 9.19026525 -1.00003309 0.016387102 2.14E-07 2.506818758 0.109777594 0.210083663 9554.881665 12.20640885 733.321933 1185.254977 0.099992381 1.00003309 2.506818544 S(ph)SELLVR ddPTM_HeLa_Curcumin_4h_R1 3 SSELLVR 7 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 0 S(0.987)S(0.013)ELLVR;S(0.993)S(0.007)ELLVR;S(0.999)S(0.001)ELLVR ;; 116.37 0.013928 49624200 5903.8 5040.44 4745.6 5905.1 6359.1 7058.2 6247.24 7975.79 6913 6416.3 TRUE FALSE FALSE 5436.508 5476.113174 4921.476111 5880.666261 6283.271886 5594.249758 6422.520741 10407.57165 6154.661195 6639.265947 0.818841728 0.824807022 0.741268108 0.885740428 0.946380509 0.842600643 0.967354041 1.567578666 0.927009288 1 12.69680803 -4.263065532 3.675189623 0.890477408 1.640487304 0.893832352 0.071148874 0.07796673 1.937117107 0.012576851 0.158866115 5.46E-05 4.263065532 0.750009897 S(ph)SENLSLDDCNK ddPTM_HeLa_Curcumin_4h_R1 2 SSENLSLDDCNK 12 0 Q96T17;Q96T17-2;Q96T17-5;Q96T17-4 Q96T17 MAP7D2 MAP7 domain-containing protein 2 1 0 S(0.991)S(0.009)ENLSLDDCNK;S(0.951)S(0.049)ENLSLDDCNK ; 214.45 3.73E-13 20835000 4304.9 3912.4 3897.2 4042.9 4630.7 3982.9 2437.6 2032.14 3728.2 3211.3 TRUE FALSE FALSE 3964.162622 4250.570423 4041.63366 4026.171551 4575.481927 3156.801643 2505.992496 2651.730131 3319.225787 3322.892436 1.192985539 1.279177856 1.216299877 1.211646669 1.37695758 0.9500162 0.754159981 0.798018649 0.998896549 1 11.69822388 -5.003634277 5.647217462 1.143959154 0.789525543 0.67278924 0.113260763 0.085988723 9.985077687 0.018537153 0.053243972 9.92E-06 5.003634277 -0.354433611 S(ph)SFSMEEGDVL ddPTM_HeLa_Curcumin_4h_R1 1 SSFSMEEGDVL 11 0 B1AKB5;B0QYS6;B0QYS7;P19484-2;P19484 B1AKB5 TFEB Transcription factor EB 1 0 S(0.436)S(0.436)FS(0.128)MEEGDVL 95.483 0.013847 1143800 679.92 462.98 558.82 442.55 689.81 635.46 507.23 176.26 853.55 651.31 TRUE FALSE FALSE 626.1036146 502.9979282 579.5303608 440.7188454 681.5844663 503.6584329 521.4615087 230.0008626 759.9177005 673.942974 0.929015716 0.746350875 0.859910086 0.653940856 1.011338485 0.747330935 0.773747229 0.341276445 1.127569735 1 9.396482712 -3.601739252 0.306700447 0.979706256 2.97E-33 0.558424219 0.140442296 6.339018852 0.317153008 0.052158846 2.503054909 0.000250185 3.601739252 -0.979706256 S(ph)SFSSDPDEKAQDSK ddPTM_HeLa_Curcumin_4h_R1 2 SSFSSDPDEKAQDSK 15 1 P46013 P46013 MKI67 Antigen KI-67 1 0 S(0.499)S(0.499)FS(0.001)S(0.001)DPDEKAQDSK;S(0.772)S(0.219)FS(0.005)S(0.004)DPDEKAQDSK ; 78.244 0.0075848 32821000 7496.7 9950.2 7850.8 9850.8 6439.5 6227.4 5940.8 4782.6 10386.2 10395.5 TRUE FALSE FALSE 6903.328285 10810.25095 8141.757554 9810.04 6362.713168 4935.767043 6107.482859 6240.792724 9246.859845 10756.74285 0.641767529 1.004974377 0.756898038 0.911989822 0.591509275 0.458853308 0.567781804 0.580174948 0.85963381 1 13.39295367 -5.671164894 5.397970064 0.840106583 0.537677541 0.671159468 0.106954349 0.133576116 6.262753158 0.020897267 0.042182881 2.13E-06 5.671164894 -0.302429042 S(ph)SGDPEQIKEDSLSEESADAR ddPTM_HeLa_Curcumin_4h_R1 2 SSGDPEQIKEDSLSEESADAR 21 1 Q9BVS4;Q9BVS4-2 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 0 S(0.9)S(0.1)GDPEQIKEDSLSEESADAR;S(0.773)S(0.227)GDPEQIKEDSLSEESADAR ; 94.72 0.00014498 21400000 6823.7 5832.4 6067.3 6291.7 6096.2 6748.9 4407.6 2780.9 6742.6 5875 TRUE FALSE FALSE 6283.596945 6336.526667 6292.159475 6265.666612 6023.506797 5349.102064 4531.265394 3628.783608 6002.953649 6079.155813 1.033629856 1.042336611 1.035038362 1.030680378 0.99084593 0.879908696 0.745377407 0.59692229 0.987465009 1 12.56965528 -4.658595282 1.227813588 1.021818028 0.542554301 0.98432921 0.017870507 0.069789934 0.137899572 0.002899307 0.035235657 2.19E-05 4.658595282 -0.479263726 S(ph)SGFISELPSEEGK ddPTM_HeLa_Curcumin_4h_R1 2 SSGFISELPSEEGK 14 0 Q5VZK9;Q5VZK9-2;A0A0U1RQQ1 Q5VZK9 LRRC16A Leucine-rich repeat-containing protein 16A 1 0 S(0.95)S(0.05)GFISELPSEEGK;S(0.875)S(0.125)GFISELPSEEGK ; 328.14 1.68E-125 44605000 8562.5 6609.6 6983.5 7742.3 7629.9 9042.5 6073.3 3398 8216.8 7418.3 TRUE FALSE FALSE 7884.76909 7180.904372 7242.314653 7710.264414 7538.918426 7166.98357 6243.700453 4434.034558 7315.437597 7676.085373 1.027186216 0.935490426 0.943490634 1.004452666 0.982130612 0.933676897 0.813396432 0.577642684 0.953016706 1 12.90615504 -3.863076449 0.939496292 1.002275888 7.42E-13 0.932244402 0.032867433 0.615859963 0.248138225 0.005103307 0.749980922 0.000137064 3.863076449 -1.002275888 S(ph)SGFLNLIK ddPTM_HeLa_Curcumin_4h_R1 1 SSGFLNLIK 9 0 Q5VZK9;Q5VZK9-2;A0A0U1RQQ1 Q5VZK9 LRRC16A Leucine-rich repeat-containing protein 16A 1 0 S(0.946)S(0.054)GFLNLIK 91.469 0.018132 5577500 1218.5 1642.6 1120.3 1289.2 1316.1 1903.5 1623.5 989.08 1276.7 1087.7 TRUE FALSE FALSE 1122.054439 1784.579025 1161.819304 1283.865632 1300.406367 1508.692643 1669.051041 1290.645939 1136.649204 1125.497494 0.99694086 1.585591291 1.032271782 1.140709454 1.155405831 1.34046735 1.482945142 1.146733729 1.00990825 1 10.13634713 -7.414501347 24.99655615 0.998527121 1.26381315 0.372268135 0.158681333 20.42733418 4697.931115 0.026091474 0.029836682 3.85E-08 7.414501347 0.265286029 S(ph)SGGGYGGGPAGGHGGNR ddPTM_HeLa_Curcumin_4h_R1 1 SSGGGYGGGPAGGHGGNR 18 0 Q9H2U1-3;Q9H2U1-2;Q9H2U1 Q9H2U1-3 DHX36 ATP-dependent RNA helicase DHX36 1 0 S(0.685)S(0.315)GGGYGGGPAGGHGGNR 184.97 1.48E-07 2281000 232.43 0 202.87 242.67 282.14 319.45 154.3 108.43 172.6 176.37 TRUE FALSE FALSE 214.0329202 0 210.3885407 241.6658958 278.7756648 253.1924691 158.6292427 141.4898078 153.6662118 182.4988444 1.172790551 0 1.152821221 1.324205075 1.527547562 1.38736478 0.869206834 0.775291528 0.842011972 1 7.511743518 -6.546880083 24.99913984 0.982453746 1.195600351 0.125556857 0.383166959 548.5222525 571323.5501 0.063139955 0.089295632 2.84E-07 6.546880083 0.213146605 S(ph)SGPYGGGGQYFAKPR ddPTM_HeLa_Curcumin_4h_R1 2 SSGPYGGGGQYFAKPR 16 1 F8W6I7;P09651-2;P09651;P09651-3;H0YH80 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 1 0 S(0.499)S(0.499)GPY(0.001)GGGGQYFAKPR;S(0.905)S(0.095)GPYGGGGQYFAKPR ; 164.92 9.41E-05 389060000 3122.7 2427.86 2723.2 2840.1 2997.7 4543.6 3011 1629.36 3224.9 2933 TRUE FALSE FALSE 2875.535 2637.7134 2824.124188 2828.348419 2961.954385 3601.206143 3095.480556 2126.144363 2871.136538 3034.921532 0.947482487 0.86912079 0.930542737 0.931934612 0.975957485 1.18658954 1.019954066 0.700559913 0.946033203 1 11.5674435 -5.523714936 24.98925533 0.959140694 0.99198429 0 0.116284341 129.4368734 3868233.427 0.016686193 0.033609864 2.99E-06 5.523714936 0.032843596 S(ph)SGREEDDEELLR ddPTM_HeLa_Curcumin_4h_R1 2 SSGREEDDEELLR 13 1 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4;A0A494C1P1;A0A494C1G0 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 S(0.967)S(0.033)GREEDDEELLR;S(0.614)S(0.386)GREEDDEELLR ; 162.88 0.0019241 165345000 6389.6 5700.9 5051.2 5927.7 5666.8 7311.1 5363.6 3353.2 6355.4 5100.7 TRUE FALSE FALSE 5883.856418 6193.660393 5238.401915 5903.172748 5599.227111 5794.695447 5514.088181 4375.575244 5658.22852 5277.948945 1.114799798 1.173497595 0.992507122 1.118459616 1.060871784 1.097906688 1.04474072 0.829029475 1.072050635 1 12.36576168 -4.265467105 4.19874983 1.066969607 0.81088322 0.665142183 0.052303624 0.115741886 4.573509469 0.008272891 0.088280615 5.43E-05 4.265467105 -0.256086386 S(ph)SGS(ph)PYGGGYGSGGGSGGYGSR ddPTM_HeLa_Curcumin_4h_R1 2 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 2 0 S(0.743)S(0.256)GS(0.976)PY(0.025)GGGYGSGGGSGGYGSR;S(0.796)S(0.061)GS(0.958)PY(0.042)GGGY(0.003)GS(0.009)GGGS(0.13)GGYGSR ; 113.33 3.52E-05 35678000 2848.1 2263.92 2727.41 3162.4 3028.6 3789.2 3491.1 1674.59 2771.5 2675.38 TRUE FALSE FALSE 2622.66988 2459.603157 2828.490214 3149.314827 2992.485923 3003.277207 3589.05087 2185.164782 2467.473384 2768.349256 0.947376807 0.888472851 1.021724484 1.137614707 1.080964014 1.084862107 1.296458842 0.789338548 0.891315783 1 11.43481025 -6.518902223 23.99233689 0.967342814 1.089466952 0.2190791 0.121983657 115.3821526 696157.9499 0.017000259 0.024387877 3.03E-07 6.518902223 0.122124138 S(ph)SGSETEQVVDFSDR ddPTM_HeLa_Curcumin_4h_R1 1 SSGSETEQVVDFSDR 15 0 O95251-4;O95251;O95251-2 O95251-4 KAT7 Histone acetyltransferase KAT7 1 0 S(0.927)S(0.064)GS(0.009)ETEQVVDFSDR 356.74 6.77E-167 37504000 2873.2 2473.3 2301.7 2932.7 2575.6 2960.4 2427 2310.4 2460.9 2171.6 TRUE FALSE FALSE 2645.783188 2687.081031 2387.003027 2920.565264 2544.887652 2346.379669 2495.095088 3014.830324 2190.945427 2247.062938 1.177440624 1.195819212 1.062276889 1.299725617 1.132539551 1.044198464 1.110380597 1.34167596 0.975026284 1 11.13382482 -9.229410004 0.751318454 0.988449281 1.166061942 0.393564533 0.089909896 0.735766482 0.672888283 0.080835669 0.017619077 5.90E-10 9.229410004 0.177612661 S(ph)SGSPYGGGYGSGGGS(ph)GGYGSR ddPTM_HeLa_Curcumin_4h_R1 1 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 2 0 S(0.935)S(0.058)GS(0.014)PY(0.001)GGGYGS(0.454)GGGS(0.533)GGYGS(0.005)R 181.32 1.26E-24 0 1513.1 1416.2 1054 1289.3 1550.8 1989.3 1576.9 626.38 1631 1207.9 TRUE FALSE FALSE 1393.336538 1538.610018 1093.062167 1283.965218 1532.307723 1576.696756 1621.14357 817.3603785 1452.083381 1249.874435 1.114781213 1.231011672 0.874537583 1.027275366 1.225969329 1.261484123 1.297045147 0.653953994 1.161783408 1 10.28756745 -5.801626817 24.99765019 1.053543425 1.133849486 0.001276971 0.190858629 431.0313278 268111.7015 0.026525637 0.048082325 1.58E-06 5.801626817 0.080306061 S(ph)SGSPYGGGYGSGGGSGGYGSR ddPTM_HeLa_Curcumin_4h_R1 4 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 0 S(0.89)S(0.099)GS(0.011)PYGGGYGSGGGSGGYGSR;S(0.477)S(0.046)GS(0.477)PYGGGYGSGGGSGGYGSR;S(0.873)S(0.023)GS(0.104)PYGGGYGSGGGSGGYGSR;S(0.476)S(0.048)GS(0.476)PYGGGYGSGGGSGGYGSR ;;; 314.43 8.21E-120 624475000 10651 8218.94 8952.94 8677.58 8832.85 12326.9 9304.04 4630.11 10407.2 7947.04 TRUE FALSE FALSE 9807.962111 8929.348551 9284.743832 8641.674473 8727.524033 9770.161987 9565.086322 6041.809225 9265.556198 8223.199048 1.192718558 1.085872846 1.129091462 1.050889614 1.061329536 1.188121792 1.16318312 0.734727347 1.126758108 1 13.00548404 -4.25536186 24.81730042 1.100328408 0.734727169 0.778437701 0.059966695 289.1502431 1180695.836 0.010878115 0.132993676 5.55E-05 4.25536186 -0.365601239 S(ph)SISGSLPSSGSLQAVSSR ddPTM_HeLa_Curcumin_4h_R1 1 SSISGSLPSSGSLQAVSSR 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 0 S(0.947)S(0.019)IS(0.019)GS(0.012)LPS(0.002)S(0.001)GSLQAVSSR 236.68 5.13E-26 11188000 1775.5 1284.2 1770.9 1603.2 1727.8 1722.9 1124.6 1253.2 2007.8 1580.1 TRUE FALSE FALSE 1634.967302 1395.200526 1836.531112 1596.566383 1707.197113 1365.551119 1156.153249 1635.294911 1787.549363 1635.008357 0.999974889 0.853329293 1.123254877 0.976488209 1.044151919 0.835195192 0.707123755 1.000175261 1.093296774 1 10.67508229 -5.250925587 24.10391993 0.998928717 0.833460606 0.376635487 0.095848976 301.7019496 691678.4302 0.011467592 0.02886589 5.61E-06 5.250925587 -0.16546811 S(ph)SKASLGSLEGEAEAEASSPK ddPTM_HeLa_Curcumin_4h_R1 1 SSKASLGSLEGEAEAEASSPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 S(0.328)S(0.328)KAS(0.328)LGS(0.017)LEGEAEAEASSPK 71.527 0.0012523 20376000 3688.1 3042.4 3178.4 3062 2481.5 2849.2 2943.8 5023 3642.2 3011.7 TRUE FALSE FALSE 3396.182993 3305.371499 3296.1943 3049.330255 2451.909733 2258.243803 3026.395105 6554.489577 3242.659772 3116.356351 1.08979289 1.060652611 1.057707762 0.978492159 0.786787343 0.724642354 0.971132555 2.103254198 1.040529197 1 11.6056445 -4.2605482 24.94561459 0.999379967 2.103254554 0.892328831 0.117870786 19.23100108 538218.0482 0.018661056 0.151155267 5.49E-05 4.2605482 1.103874587 S(ph)SLETLEDIEENAPLR ddPTM_HeLa_Curcumin_4h_R1 1 SSLETLEDIEENAPLR 16 0 V9GYB4;Q8TDN4-2;Q8TDN4 V9GYB4 CABLES1 CDK5 and ABL1 enzyme substrate 1 1 0 S(0.787)S(0.213)LETLEDIEENAPLR 121.72 0.0008324 4527500 1293.4 1124.2 1229.7 1316.7 1210.2 1254.3 919.88 602.84 1092.1 842.94 TRUE FALSE FALSE 1191.026025 1221.370839 1275.273764 1311.251844 1195.769155 994.1440411 945.6893571 786.6431409 972.2993623 872.2321023 1.365492077 1.400281915 1.462080747 1.503329035 1.370929999 1.139770066 1.084217555 0.90187364 1.114725495 1 9.768568279 -4.571540588 1.87328556 1.251605001 0.896483252 0.382717067 0.156909116 0.571493191 3.131321823 0.030178457 0.284812934 2.68E-05 4.571540588 -0.355121749 S(ph)SLETLEDIEENAPLRR ddPTM_HeLa_Curcumin_4h_R1 3 SSLETLEDIEENAPLRR 17 1 V9GYB4;Q8TDN4-2;Q8TDN4 V9GYB4 CABLES1 CDK5 and ABL1 enzyme substrate 1 1 0 S(0.392)S(0.392)LET(0.217)LEDIEENAPLRR;S(0.498)S(0.498)LET(0.004)LEDIEENAPLRR;S(0.5)S(0.5)LETLEDIEENAPLRR ;; 169.58 3.37E-05 38154800 2242.03 2106.5 2123.03 1953.67 1950.53 3120.57 2550.63 1184.21 2443.28 2012.01 TRUE FALSE FALSE 2064.57096 2288.576474 2201.711359 1945.586231 1927.271204 2473.328606 2622.193813 1545.270178 2175.258297 2081.927198 0.991663379 1.099258647 1.057535231 0.934512135 0.925714985 1.187999565 1.259503126 0.74223065 1.044829185 1 11.02370391 -5.27509058 24.95887359 0.999852114 1.082870327 0.026086756 0.135407291 1487.686669 2719976.47 0.017770401 0.039934535 5.31E-06 5.27509058 0.083018212 S(ph)SLGSHQLPR ddPTM_HeLa_Curcumin_4h_R1 3 SSLGSHQLPR 10 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 0 S(0.988)S(0.012)LGSHQLPR;S(0.944)S(0.055)LGS(0.001)HQLPR;S(0.498)S(0.498)LGS(0.004)HQLPR ;; 126.66 0.0034134 38673000 5475.8 4911.5 4392.8 5125.6 6155.8 10411.7 7310.2 5988.6 6377.8 5064.1 TRUE FALSE FALSE 5042.384652 5336.028175 4555.601032 5104.391625 6082.396105 8252.196056 7515.304538 7814.496572 5678.171296 5240.077098 0.962272989 1.018311005 0.869376719 0.974106207 1.160745537 1.574823405 1.434197321 1.491294198 1.083604533 1 12.35537232 -5.455837196 3.206349447 0.97570784 1.492814364 0.931091784 0.062481828 0.036044045 0.722557797 0.007552486 0.017775058 3.50E-06 5.455837196 0.517106524 S(ph)SLGSLQT(ph)PEAVTTR ddPTM_HeLa_Curcumin_4h_R1 1 SSLGSLQTPEAVTTR 15 0 Q7Z2W4-2;Q7Z2W4;C9J6P4;Q7Z2W4-3 Q7Z2W4-2 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 2 0 S(0.931)S(0.071)LGS(0.011)LQT(0.987)PEAVTTR 109.1 0.010466 31733000 2361.1 2036.2 2089.2 2099.4 2167.7 3190.2 2798.8 1078.3 2252 1548.7 TRUE FALSE FALSE 2174.216444 2212.200055 2166.62759 2090.713239 2141.851593 2528.516559 2877.326795 1407.068706 2004.961234 1602.51721 1.356750761 1.380453228 1.352015178 1.304643237 1.336554503 1.577840502 1.795504459 0.878036565 1.25113242 1 10.64612413 -9.267722999 0.429191812 0.884661434 1.415283437 0.105233403 0.23199034 1.875226264 0.455202691 0.446395466 0.066454202 5.40E-10 9.267722999 0.530622003 S(ph)SLGSLQTPEAVTTR ddPTM_HeLa_Curcumin_4h_R1 2 SSLGSLQTPEAVTTR 15 0 Q7Z2W4-2;Q7Z2W4;C9J6P4;Q7Z2W4-3 Q7Z2W4-2 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 0 S(0.498)S(0.498)LGS(0.003)LQTPEAVTTR;S(0.905)S(0.094)LGS(0.001)LQTPEAVTTR ; 200 1.88E-07 54418000 3340.5 3068.6 2821.56 3712.9 3405.5 4572 3730 1459.12 3816.6 3001 TRUE FALSE FALSE 3076.0959 3333.836111 2926.129496 3697.537004 3364.891637 3623.715663 3834.653761 1903.998971 3397.928529 3105.284527 0.990600338 1.073600851 0.942306404 1.190724061 1.083601714 1.166951251 1.234880002 0.613147992 1.09424064 1 11.60050975 -6.297399969 24.7983113 0.998912023 1.075186137 0 0.166961822 1342.987947 926117.6373 0.023188098 0.03542089 5.04E-07 6.297399969 0.076274114 S(ph)SLS(ph)GDEEDELFK ddPTM_HeLa_Curcumin_4h_R1 2 SSLSGDEEDELFK 13 0 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 2 0 S(0.937)S(0.063)LS(1)GDEEDELFK;S(0.995)S(0.005)LS(1)GDEEDELFK ; 193.45 1.36E-05 100245000 17550.5 14468.3 15159.2 15550.7 16272 18635.5 16017.4 15241.7 15848 14575.7 TRUE FALSE FALSE 16161.35941 15718.87538 15721.01329 15486.35532 16077.96703 14770.28723 16466.80514 19888.82417 14109.51405 15082.20449 1.071551537 1.042213384 1.042355134 1.026796536 1.066022347 0.979318855 1.091803598 1.318694769 0.935507409 1 13.8805597 -4.29007257 3.25308494 1.03449357 1.349782186 0.823228704 0.041060602 0.070320736 1.205367374 0.004341031 0.053457916 5.13E-05 4.29007257 0.315288616 GLS(ph)EDTTEETLKESFDGSVR ddPTM_HeLa_Curcumin_4h_R1 1 GLSEDTTEETLKESFDGSVR 20 1 P19338;H7BY16 P19338 NCL Nucleolin 1 0 GLS(0.976)EDT(0.019)T(0.005)EETLKESFDGSVR 67.785 0.0032537 10967000 1630 1443.4 1225.7 1244.5 1644.9 2397.4 2101.9 2220.7 1654.9 1214.1 TRUE FALSE FALSE 1500.98378 1568.161064 1271.12552 1239.350589 1625.285642 1900.152216 2160.873657 2897.781207 1473.36161 1256.289885 1.194775026 1.248247784 1.011809086 0.986516411 1.293718641 1.512510957 1.720043824 2.306618275 1.172787928 1 10.29495368 -4.144804906 0.80566054 1.090450177 3.19691346 0.935243416 0.099087596 0.53364917 0.220205529 0.018214134 1.046657439 7.16E-05 4.144804906 2.106463283 up S(ph)SLSNNSLK ddPTM_HeLa_Curcumin_4h_R1 1 SSLSNNSLK 9 0 Q9ULJ7-2;Q9ULJ7 Q9ULJ7-2 ANKRD50 Ankyrin repeat domain-containing protein 50 1 0 S(0.73)S(0.14)LS(0.052)NNS(0.078)LK 120.63 0.0060719 14540000 3859.7 3768 3321.6 3383.7 3772.8 4256.3 3879.2 2242.2 3179.1 3078.3 TRUE FALSE FALSE 3554.200672 4093.68913 3444.701418 3369.699146 3727.811824 3373.495402 3988.039912 2925.836458 2830.360684 3185.270696 1.115823744 1.28519348 1.081446994 1.057900401 1.170328107 1.059092217 1.25202543 0.918551903 0.888577755 1 11.63720027 -8.90192401 0.973405214 1.00666854 1.12190257 0.257519428 0.105916226 0.630084772 1.164423545 0.043465381 0.017600611 1.25E-09 8.90192401 0.11523403 S(ph)SLSRRSS(ph)MES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SSLSRRSSMESPK 13 2 Q5T1R4-2;Q5T1R4 Q5T1R4-2 HIVEP3 Transcription factor HIVEP3 3 0 S(0.455)S(0.456)LS(0.073)RRS(0.042)S(0.983)MES(0.992)PK 48.284 0.0096281 0 1687.5 1470 1434.1 1610.7 1334.4 1982.3 1388.4 782.56 1510.7 1525.4 TRUE FALSE FALSE 1553.932594 1597.06025 1487.249008 1604.03535 1318.488152 1571.148635 1427.354767 1021.158942 1344.97999 1578.407536 0.984493902 1.011817425 0.942246519 1.0162365 0.835328089 0.995401123 0.904300527 0.646955186 0.852111992 1 10.62425403 -3.762081425 1.215272279 0.984102488 2.77E-16 0.638676916 0.06612044 1.347846259 0.717850311 0.007154999 2.245353133 0.000172949 3.762081425 -0.984102488 S(ph)SPAAFINPPIGTVTPALK ddPTM_HeLa_Curcumin_4h_R1 2 SSPAAFINPPIGTVTPALK 19 0 Q6R954;F8WEE2;Q8WUT1;F8WCX5;F6VRR5;Q9BY77-2;Q9BY77 Q6R954 PDIP46;POLDIP3 Polymerase delta-interacting protein 3 1 0 S(0.5)S(0.5)PAAFINPPIGTVTPALK;S(0.5)S(0.5)PAAFINPPIGTVTPALK ; 240.34 2.80E-33 74002000 4501.3 2931.6 3555.2 3586.4 3569.9 4770.7 4082.9 1629.18 4345.5 3314.6 TRUE FALSE FALSE 4145.017355 3184.994441 3686.958839 3571.560427 3527.331274 3781.203043 4197.455185 2125.909482 3868.809522 3429.782103 1.208536645 0.928628801 1.074983404 1.041337414 1.028441798 1.102461594 1.223825613 0.619838059 1.128004464 1 11.74390121 -4.250697928 24.77308758 1.085475808 0.61983776 0.722837256 0.085790518 632.6336923 1459016.17 0.013545388 0.262046206 5.61E-05 4.250697928 -0.465638048 S(ph)SPAFGDR ddPTM_HeLa_Curcumin_4h_R1 1 SSPAFGDR 8 0 P13716;P13716-2 P13716 ALAD Delta-aminolevulinic acid dehydratase 1 0 S(0.5)S(0.5)PAFGDR 91.265 0.020166 6911000 1633.1 1589.7 1697.4 1617.5 1841.5 1806.3 1777.3 1255.9 1757.5 1563.2 TRUE FALSE FALSE 1503.838412 1727.106584 1760.307137 1610.807214 1819.541315 1431.653019 1827.166255 1638.818129 1564.706647 1617.521084 0.929717966 1.06774904 1.088274617 0.995849284 1.12489496 0.885090793 1.129608926 1.013166471 0.967348533 1 10.6595688 -7.255426089 24.83046805 0.966811262 1.043754649 0.211551414 0.068843984 493.195767 2036537.428 0.010885329 0.013145175 5.55E-08 7.255426089 0.076943387 S(ph)SPAFGDRR ddPTM_HeLa_Curcumin_4h_R1 2 SSPAFGDRR 9 1 P13716;P13716-2 P13716 ALAD Delta-aminolevulinic acid dehydratase 1 0 S(0.5)S(0.5)PAFGDRR;S(0.5)S(0.5)PAFGDRR ; 112.85 0.0038579 24576000 1811.72 1626.74 1920.46 1838.36 1579.29 1867.61 1745.29 1804.47 2059.8 1558.06 TRUE FALSE FALSE 1668.32045 1767.348157 1991.633937 1830.753353 1560.457998 1480.246634 1794.25814 2354.644596 1833.845093 1612.202469 1.034808271 1.096232136 1.235349762 1.135560445 0.967904484 0.918151822 1.112923578 1.460514198 1.137478157 1 10.65481722 -4.288017199 3.655414822 1.037323815 1.496134377 0.611705948 0.091354233 0.115176252 2.807831468 0.012879064 0.137080146 5.15E-05 4.288017199 0.458810562 S(ph)SPAPHSGPCPSR ddPTM_HeLa_Curcumin_4h_R1 2 SSPAPHSGPCPSR 13 0 P85299-2;P85299-4;P85299-3;P85299;P85299-5 P85299-2 PRR5 Proline-rich protein 5 1 0 S(0.5)S(0.5)PAPHSGPCPSR;S(0.5)S(0.5)PAPHSGPCPSR ; 70.134 0.016783 6454300 1276.14 1246.1 1138.37 1094.8 1398.03 1629.64 907.52 387.52 1951.39 1112.66 TRUE FALSE FALSE 1175.132172 1353.807331 1180.558994 1090.270008 1381.359405 1291.634294 932.9825687 505.6730641 1737.327399 1151.324852 1.020678195 1.175869112 1.02539174 0.946969924 1.199799868 1.121867813 0.810355624 0.439209718 1.508981063 1 10.16907924 -4.396294591 2.762260906 1.037532549 0.40616044 0.583363733 0.169907068 0.098654979 1.172985545 0.0118686 0.120020912 4.02E-05 4.396294591 -0.631372108 S(ph)SPELLPSGVTDENEVTTAVTEK ddPTM_HeLa_Curcumin_4h_R1 2 SSPELLPSGVTDENEVTTAVTEK 23 0 P42566;B1AUU8;P42566-2 P42566 EPS15 Epidermal growth factor receptor substrate 15 1 0 S(0.5)S(0.5)PELLPSGVTDENEVTTAVTEK;S(0.5)S(0.5)PELLPSGVTDENEVTTAVTEK ; 143.21 4.40E-06 35487000 13805 11783.6 13037.8 11591.3 13462.7 13893.1 10845.2 10475.1 11910.7 11812.2 TRUE FALSE FALSE 12712.31968 12802.12188 13520.99234 11543.33827 13302.1661 11011.51445 11149.48712 13668.90977 10604.12601 12222.67307 1.040060518 1.047407699 1.106222204 0.944420112 1.088318899 0.900908859 0.912197116 1.118324092 0.867578307 1 13.57727221 -5.266404444 24.99143522 1.026504731 0.970648733 0.019217953 0.085780424 653.3621594 3288680.31 0.009253884 0.021327608 5.41E-06 5.266404444 -0.055855997 S(ph)SPEQPRPSTSK ddPTM_HeLa_Curcumin_4h_R1 1 SSPEQPRPSTSK 12 1 P29590;P29590-5;P29590-4;P29590-9;P29590-3;P29590-8;P29590-11;H3BVD2;P29590-12;H3BT57;P29590-13;H3BRN3;H3BUJ5;P29590-2 P29590;P29590-2 PML Protein PML 1 0 S(0.992)S(0.008)PEQPRPSTSK 182.25 0.00072976 114800000 7441.6 6467.4 6333.4 6392.7 6155.6 7609 6470.9 3620 7146.5 6218.9 TRUE FALSE FALSE 6852.589508 7026.413238 6568.121375 6366.248701 6082.19849 6030.807629 6652.456038 4723.721336 6362.54683 6435.006312 1.06489243 1.091904638 1.020686081 0.989315067 0.945173663 0.937187523 1.033791688 0.73406631 0.988739796 1 12.65172585 -3.726630388 1.536227145 1.023117363 3.52E-49 0.71211149 0.050438005 2.136693518 1.47122174 0.00785617 4.978738807 0.000187659 3.726630388 -1.023117363 S(ph)SPGAGPSDHHSASR ddPTM_HeLa_Curcumin_4h_R1 1 SSPGAGPSDHHSASR 15 0 I3VM54;Q9Y2K7-3;Q9Y2K7;Q9Y2K7-4;Q9Y2K7-5;Q9Y2K7-2 I3VM54 KDM2A Lysine-specific demethylase 2A 1 0 S(0.5)S(0.5)PGAGPSDHHSASR 102.5 0.0014661 570310 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 S(ph)SPGAVAGLSNAPGTPR ddPTM_HeLa_Curcumin_4h_R1 2 SSPGAVAGLSNAPGTPR 17 0 V9GYB2;U3KPY3;Q9BWG4-2;Q9BWG4 V9GYB2 SSBP4 Single-stranded DNA-binding protein 4 1 0 S(0.901)S(0.099)PGAVAGLSNAPGTPR;S(0.864)S(0.136)PGAVAGLSNAPGTPR ; 228.99 4.16E-22 42132000 1636.03 1471.53 1737.47 1691.15 1994.49 1708.57 1360.38 893.2 1906.25 1237.03 TRUE FALSE FALSE 1506.536499 1598.722496 1801.862167 1684.152469 1970.707009 1354.193322 1398.548602 1165.532568 1697.139144 1280.0167 1.176966284 1.248985654 1.407686451 1.31572695 1.539594764 1.05794973 1.09260184 0.910560439 1.325872657 1 10.32194692 -8.486125503 0.904658881 1.019886829 1.230340178 0 0.195161859 0.648701234 1.093988061 0.06860713 0.037758924 3.26E-09 8.486125503 0.210453349 S(ph)SPGGQDEGGFMAQGK ddPTM_HeLa_Curcumin_4h_R1 3 SSPGGQDEGGFMAQGK 16 0 A0A1B0GTU4;F5GZ78;P49023;A0A1B0GV30 A0A1B0GTU4 PXN Paxillin 1 0 S(0.5)S(0.5)PGGQDEGGFMAQGK;S(0.5)S(0.5)PGGQDEGGFMAQGK;S(0.842)S(0.158)PGGQDEGGFMAQGK ;; 171.15 0.00010964 369125000 12395.4 11157.6 11691.7 12084.2 11439 10506.9 6515.3 5147.4 11202 9656.9 TRUE FALSE FALSE 11414.29101 12122.01323 12125.00469 12034.19878 11302.5974 8327.650503 6698.101783 6716.818564 9973.168626 9992.476556 1.142288495 1.213114002 1.213413373 1.204325946 1.131110724 0.833392048 0.670314486 0.672187573 0.998067753 1 13.28662657 -5.075609214 2.936069826 1.105434725 0.674905917 0.856040662 0.077149357 0.08876892 1.482171977 0.013758778 0.042799288 8.40E-06 5.075609214 -0.430528808 S(ph)SPGPDTLVVLEFNPASK ddPTM_HeLa_Curcumin_4h_R1 2 SSPGPDTLVVLEFNPASK 18 0 O60303 O60303 KIAA0556 Uncharacterized protein KIAA0556 1 0 S(0.603)S(0.397)PGPDTLVVLEFNPASK;S(0.5)S(0.5)PGPDTLVVLEFNPASK ; 191.37 6.73E-09 19938500 3109.1 2511.4 3021.4 2653.9 2894.4 2358.9 1843.83 1119.35 2868 2373.8 TRUE FALSE FALSE 2863.011454 2728.474225 3133.375742 2642.918865 2859.88617 1869.63755 1895.562907 1460.634662 2553.387575 2456.289373 1.165583944 1.110811395 1.275654154 1.075980254 1.164311584 0.761163391 0.771718075 0.59465089 1.039530441 1 11.26226482 -5.181543303 4.420295618 1.10239939 0.702469883 0.83216107 0.084290416 0.077725816 2.799794797 0.013635313 0.036228891 6.58E-06 5.181543303 -0.399929507 S(ph)SPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR ddPTM_HeLa_Curcumin_4h_R1 2 SSPGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR 36 1 P40222 P40222 TXLNA Alpha-taxilin 1 0 S(0.5)S(0.5)PGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR;S(0.5)S(0.5)PGQPEAGPEGAQERPSQAAPAVEAEGPGSSQAPR ; 95.628 1.77E-11 225750000 731.45 493.27 627.07 777.52 707.36 745.79 771.33 431.64 726.03 706.34 TRUE FALSE FALSE 673.5549607 535.9060608 650.3097658 774.3028283 698.925194 591.1047472 792.9714439 563.245049 646.3863254 730.8852624 0.921560463 0.733228714 0.889756299 1.059404079 0.956272113 0.808751767 1.08494655 0.770634021 0.884388233 1 9.513501133 -8.707051852 1.112787973 0.991136653 0.909464721 0 0.113168403 0.824677426 2.048151516 0.038125081 0.020043937 1.96E-09 8.707051852 -0.081671932 S(ph)SPGQTPEEGAQALAEFAALHGPALR ddPTM_HeLa_Curcumin_4h_R1 5 SSPGQTPEEGAQALAEFAALHGPALR 26 0 Q14166 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 1 0 S(0.5)S(0.5)PGQTPEEGAQALAEFAALHGPALR;S(0.488)S(0.488)PGQT(0.025)PEEGAQALAEFAALHGPALR;S(0.5)S(0.5)PGQTPEEGAQALAEFAALHGPALR;S(0.5)S(0.5)PGQT(0.001)PEEGAQALAEFAALHGPALR;S(0.475)S(0.475)PGQT(0.049)PEEGAQALAEFAALHGPALR ;;;; 190.56 8.39E-18 1375512300 15538.69 13101.07 13743.85 13950.68 12968.75 17248.84 10799.58 11252.96 15230.2 13740.2 TRUE FALSE FALSE 14308.78629 14233.46811 14253.20917 13892.95578 12814.10613 13671.23615 11102.58715 14683.9357 13559.48516 14217.67093 1.0064086 1.001111095 1.002499583 0.977161158 0.901280258 0.961566505 0.780900557 1.032794737 0.953706499 1 13.79539753 -5.892379725 3.327206171 1.002671991 0.911891649 0.237157658 0.060750552 0.187989663 4.120984115 0.007699399 0.014673394 1.28E-06 5.892379725 -0.090780342 S(ph)SPLPAK ddPTM_HeLa_Curcumin_4h_R1 1 SSPLPAK 7 0 Q7L2J0 Q7L2J0 MEPCE 7SK snRNA methylphosphate capping enzyme 1 0 S(0.99)S(0.01)PLPAK 118.74 0.012695 42764000 8973.4 8534.3 10740 9257.1 10405 9285.6 4102.2 3175.4 8233.6 7972.9 TRUE FALSE FALSE 8263.145921 9271.966864 11138.03385 9218.796573 10280.92717 7359.66189 4217.296691 4143.564842 7330.394679 8249.957682 1.001598583 1.123880536 1.350071634 1.11743562 1.246179383 0.892084805 0.5111901 0.50225286 0.888537246 1 13.010171 -4.856352421 3.525331713 1.060635957 0.497554708 0.767698257 0.128390499 0.086757992 2.070929 0.019151719 0.068024428 1.39E-05 4.856352421 -0.56308125 S(ph)SPNPFITGLTR ddPTM_HeLa_Curcumin_4h_R1 3 SSPNPFITGLTR 12 0 J3KQV8;O43426;A0A0D9SGJ6 J3KQV8 SYNJ1 Synaptojanin-1 1 0 S(0.907)S(0.093)PNPFITGLTR;S(0.843)S(0.157)PNPFITGLTR;S(0.832)S(0.168)PNPFITGLTR ;; 172.58 0.0001357 29492900 3724.8 2477.52 2939.94 2970.71 3109.29 3085.8 1732.44 1290.41 3012.79 2900.17 TRUE FALSE FALSE 3429.97815 2691.665789 3048.896763 2958.417989 3072.213747 2445.770296 1781.047604 1683.850069 2682.294475 3000.950692 1.142963848 0.896937693 1.015976961 0.985826924 1.023746827 0.814998495 0.593494458 0.561105543 0.893814911 1 11.5512039 -4.964449185 1.63634681 1.046684773 0.53801743 0.805301001 0.079021873 0.108779525 0.528725112 0.011291612 0.056906639 1.09E-05 4.964449185 -0.508667343 S(ph)SPNPFVGSPPK ddPTM_HeLa_Curcumin_4h_R1 1 SSPNPFVGSPPK 12 0 P98082-3;P98082 P98082-3 DAB2 Disabled homolog 2 1 0 S(0.5)S(0.5)PNPFVGSPPK 110.98 0.0052891 13394000 4854 4350.1 3865.6 5031.6 4777.8 3812.3 2282.3 2306.6 5258.4 4353.9 TRUE FALSE FALSE 4469.800778 4726.10326 4008.862537 5010.780572 4720.827855 3021.586007 2346.335196 3009.871722 4681.566676 4505.197701 0.992143092 1.049033488 0.889830547 1.112222128 1.047862529 0.670688881 0.520806267 0.66808871 1.039147888 1 12.1373747 -5.184127637 4.502862532 1.00399949 0.59704784 0.886926522 0.065309049 0.046659657 1.759862187 0.008388338 0.022219263 6.54E-06 5.184127637 -0.40695165 S(ph)SPNVANQPPS(ph)PGGK ddPTM_HeLa_Curcumin_4h_R1 2 SSPNVANQPPSPGGK 15 0 A8MQ02;J3KN01;P55196-3;P55196;P55196-5;Q5TIG5;P55196-2;P55196-6;P55196-1 A8MQ02 MLLT4 Afadin 2 0 S(0.759)S(0.241)PNVANQPPS(1)PGGK;S(0.805)S(0.195)PNVANQPPS(1)PGGK ; 154.72 0.00092243 18073500 6481 6365.2 6351.9 5943.9 6222.4 6873.4 6298 6549.8 7814.3 7089.9 TRUE FALSE FALSE 5968.022011 6915.379525 6587.307002 5919.305717 6148.201944 5447.779361 6474.70493 8546.803868 6957.09084 7336.273497 0.813495028 0.94262837 0.897909137 0.806854559 0.838055172 0.74258128 0.882560462 1.165006167 0.948313997 1 12.84083171 -9.510636278 1.232970921 1.00071347 0.871807339 0.076876728 0.109262612 0.699708313 1.886916249 0.076725451 0.018086811 3.09E-10 9.510636278 -0.128906131 S(ph)SPPLPPPAEER ddPTM_HeLa_Curcumin_4h_R1 2 SSPPLPPPAEER 12 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 0 S(0.987)S(0.013)PPLPPPAEER;S(0.981)S(0.019)PPLPPPAEER ; 179.6 0.00010596 233030000 10499.4 8505.2 8827.2 9257.6 8697.6 10662.9 8705.2 6331.5 10285.6 9276.1 TRUE FALSE FALSE 9668.361411 9240.35159 9154.343797 9219.294504 8593.886801 8451.294344 8949.444483 8261.945203 9157.295413 9598.443785 1.007284267 0.962692682 0.953732084 0.96049888 0.895341682 0.880485893 0.932384945 0.860758826 0.954039594 1 13.2285848 -6.224657334 0.778572856 1.004261705 0.886865886 0.678436891 0.026181138 0.17172264 0.203684942 0.003939687 0.009711064 5.96E-07 6.224657334 -0.117395819 S(ph)SPPPGYVPER ddPTM_HeLa_Curcumin_4h_R1 1 SSPPPGYVPER 11 0 J3KRN4;J3QRB6;Q99759;Q99759-2 J3KRN4 MAP3K3 Mitogen-activated protein kinase kinase kinase 3 1 0 S(0.918)S(0.082)PPPGYVPER 147.28 0.00083796 23727000 1967.8 1601.9 1723.6 1802.3 1841.4 1658.2 1444.4 914.96 1757.2 1520.8 TRUE FALSE FALSE 1812.046554 1740.361098 1787.478132 1794.84256 1819.442508 1314.270628 1484.925977 1193.927092 1564.439556 1573.647687 1.151494435 1.105940747 1.135882032 1.140561877 1.156194314 0.835174632 0.943620347 0.758700376 0.994148544 1 10.61989687 -5.254718358 24.96697322 1.090865797 0.855610624 0.734972026 0.069161283 238.2586181 885070.0949 0.010805394 0.026873485 5.56E-06 5.254718358 -0.235255172 S(ph)SPPSAGNSPSSLK ddPTM_HeLa_Curcumin_4h_R1 2 SSPPSAGNSPSSLK 14 0 P57682;P57682-2 P57682 KLF3 Krueppel-like factor 3 1 0 S(0.982)S(0.018)PPSAGNSPSSLK;S(0.916)S(0.084)PPSAGNSPSSLK ; 170.26 0.00020291 19175600 3520.8 2463.1 3607.2 3830.2 3802.4 4440 3636.5 2497.8 3479.7 3229.9 TRUE FALSE FALSE 3242.124965 2675.999389 3740.886005 3814.351647 3757.058863 3519.093951 3738.530403 3259.367722 3097.985616 3342.138785 0.970074905 0.8006847 1.119308995 1.141290621 1.12414807 1.052946684 1.118604176 0.975234104 0.926947029 1 11.70655593 S(ph)SPQLDPLR ddPTM_HeLa_Curcumin_4h_R1 2 SSPQLDPLR 9 0 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 0 S(0.901)S(0.099)PQLDPLR;S(0.981)S(0.019)PQLDPLR ; 135.1 0.0031177 66570500 7745.6 6213 7089.9 7397.7 8399.5 12069.1 11864.1 3589.6 6488.5 6404 TRUE FALSE FALSE 7132.527587 6750.024035 7352.657931 7367.090278 8299.341448 9565.832613 12196.97472 4684.052516 5776.727783 6626.538523 1.076357975 1.018634995 1.109577482 1.111755444 1.252439931 1.443564024 1.840625339 0.70686264 0.871756463 1 12.69403974 -5.716203214 2.260346373 1.042020636 1.377687545 0.209097199 0.266091034 0.298194189 3.101811737 0.035553118 0.078183821 1.92E-06 5.716203214 0.335666909 S(ph)SPSVKPAVDPAAAK ddPTM_HeLa_Curcumin_4h_R1 2 SSPSVKPAVDPAAAK 15 1 H3BV90;Q6FI81-3;Q6FI81;H3BPG7;H3BT65 H3BV90 CIAPIN1 Anamorsin 1 0 S(0.66)S(0.293)PS(0.047)VKPAVDPAAAK;S(0.5)S(0.5)PSVKPAVDPAAAK ; 161.82 0.0027568 23304000 4519.9 4299.8 3649 4778 4457.8 5418.5 3658.3 2197.44 4903.9 4055.8 TRUE FALSE FALSE 4162.145146 4671.455552 3784.23515 4758.229902 4404.643646 4294.642021 3760.942052 2867.42934 4365.954439 4196.738748 0.991757027 1.113115644 0.901708535 1.133792258 1.049539633 1.023328417 0.89615825 0.683251809 1.040320759 1 12.03505294 -4.352316393 2.286989699 1.012769589 0.636124499 0.736440582 0.0635787 0.182198178 1.276334065 0.008400078 0.126151427 4.44E-05 4.352316393 -0.37664509 S(ph)SPSVLIHSLGK ddPTM_HeLa_Curcumin_4h_R1 2 SSPSVLIHSLGK 12 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3 RAI14 Ankycorbin 1 0 S(0.499)S(0.499)PS(0.001)VLIHSLGK;S(0.499)S(0.499)PS(0.003)VLIHSLGK ; 118.73 0.001746 37586000 11786.5 9637.8 8771.9 8793.5 12091.9 18396.8 8719.2 8351.2 10108 7769.1 TRUE FALSE FALSE 10853.58609 10470.84849 9096.994331 8757.114827 11947.71199 14581.09631 8963.837285 10897.44244 8999.177689 8039.075647 1.350103739 1.302494086 1.131597055 1.089318625 1.486204698 1.813777721 1.11503333 1.355559136 1.119429408 1 12.97281391 -12.3924332 0.214519162 8.15E-12 1.397038672 0.230799481 0.201569725 30.82279986 0.592645683 13.30875514 0.190734722 4.05E-13 12.3924332 1.397038672 S(ph)SPVCSTAPVETEPK ddPTM_HeLa_Curcumin_4h_R1 2 SSPVCSTAPVETEPK 15 0 Q96BY7 Q96BY7 ATG2B Autophagy-related protein 2 homolog B 1 0 S(0.93)S(0.07)PVCSTAPVETEPK;S(0.499)S(0.499)PVCST(0.001)APVETEPK ; 240.46 5.18E-29 14782300 4242.5 3940 3496.7 3617.4 4188.1 4860.7 3263.6 3098.16 4084.8 4004.8 TRUE FALSE FALSE 3906.701648 4280.556044 3626.290778 3602.432157 4138.159643 3852.536029 3355.167832 4042.774722 3636.70766 4143.966502 0.942744505 1.032961063 0.875077242 0.869319806 0.99859872 0.929673545 0.809651292 0.975580937 0.877590989 1 12.01679663 -7.927376144 0.173193146 1.040313037 0.873846013 0 0.071254695 5.174902311 0.646596029 0.324991396 0.223011383 1.18E-08 7.927376144 -0.166467024 S(ph)SPVEFECINEK ddPTM_HeLa_Curcumin_4h_R1 1 SSPVEFECINEK 12 0 H0YB26;O75131 H0YB26 CPNE3 Copine-3 1 0 S(0.991)S(0.009)PVEFECINEK 249.28 1.01E-27 29504000 2514 1992.9 2199.2 2465.2 2418 2787.9 2358 1893.6 2227.1 1743.8 TRUE FALSE FALSE 2315.014247 2165.157396 2280.704287 2454.999656 2389.166929 2209.658114 2424.159134 2470.949923 1982.792702 1804.39692 1.282985036 1.199934101 1.263970394 1.360565199 1.324080585 1.224596478 1.343473327 1.369404866 1.098867261 1 10.81730101 -11.13150226 0.244293631 0.50494866 1.342838739 0.75400204 0.056633309 3.976783157 0.144089073 1.068465669 0.035625544 7.39E-12 11.13150226 0.837890078 S(ph)SPVESLKK ddPTM_HeLa_Curcumin_4h_R1 1 SSPVESLKK 9 1 B1AKL4;Q9NRA8;Q9NRA8-3;Q9NRA8-2;B1AKL5 B1AKL4 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 0 S(0.88)S(0.12)PVESLKK 112.71 0.013034 117800000 5240.8 4036.4 4040 3894.8 4383.4 4484.9 3254.1 1937.4 4684.1 3760.7 TRUE FALSE FALSE 4825.98515 4385.28843 4189.725954 3878.68435 4331.130818 3554.681185 3345.401288 2528.104341 4170.265949 3891.384045 1.240171901 1.12692255 1.0766673 0.996736458 1.113005236 0.91347478 0.859694456 0.64966714 1.071666508 1 11.92606765 -4.179938545 0.736119171 1.112987669 0.326033518 0.809670807 0.068601092 1.237342806 0.435063536 0.015984111 0.825738765 6.61E-05 4.179938545 -0.786954151 DVYLS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 DVYLSPR 7 0 P38159;P38159-2;H3BUY5;Q96E39;H0Y6E7;H3BT71 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 1 0 DVYLS(1)PR;DVYLS(1)PR ; 144.65 0.0019065 527030000 12417.6 11006 10752.8 12131.8 12497.3 14884.2 10459.9 4430.9 11956.6 11619.4 TRUE FALSE FALSE 11434.73386 11957.3096 11151.30823 12081.60183 12348.27786 11797.04914 10753.37664 5781.861013 10644.99089 12023.17329 0.951057893 0.994521938 0.927484613 1.004859661 1.027039831 0.98119264 0.894387562 0.480893095 0.885372825 1 13.5535301 -4.248886987 2.713159219 0.9797657 0.375096832 0.930023426 0.040097534 0.061603442 0.584523562 0.004154421 0.084386 5.64E-05 4.248886987 -0.604668868 down S(ph)SPVLQHK ddPTM_HeLa_Curcumin_4h_R1 3 SSPVLQHK 8 0 Q3V6T2;Q3V6T2-3;Q3V6T2-2;Q3V6T2-4;Q3V6T2-5;A0A2U3TZV9;A0A2R8Y7B1;A0A2R8Y7D4;H7C2C6;A0A2R8Y820;A0A2R8Y885;A0A2R8YCU9;A0A2R8YDS8;H0Y470;H0Y7U8;A0A2R8Y5D7;H0Y7K3;A0A2R8Y4Z5;A0A2R8Y4C6 Q3V6T2 CCDC88A Girdin 1 0 S(0.5)S(0.5)PVLQHK;S(0.5)S(0.5)PVLQHK;S(0.5)S(0.5)PVLQHK ;; 125.71 0.0030666 32269500 18025.3 26247.7 15076.4 14057.9 14152.4 20974.3 13237.8 4905.69 14102.7 17218.5 TRUE FALSE FALSE 16598.57848 28516.43423 15635.14465 13999.73213 13983.64187 16623.99375 13609.21704 6401.412298 12555.66909 17816.84159 0.931622948 1.600532512 0.877548614 0.785758355 0.784855262 0.933049422 0.763840043 0.35928996 0.704707904 1 14.12095399 -6.525568499 24.99798357 1.024973589 0.751271495 0.274834723 0.251464535 92.83730682 862805.6944 0.036720804 0.052102948 2.98E-07 6.525568499 -0.273702095 S(ph)SPVNNHHSPGQTPTLGQPEAR ddPTM_HeLa_Curcumin_4h_R1 1 SSPVNNHHSPGQTPTLGQPEAR 22 0 H0Y2V6;Q5SW79;Q5SW79-3;Q5SW79-2;E7EWM2;E7EMW0;Q96L14 H0Y2V6 CEP170;CEP170P1 Centrosomal protein of 170 kDa;Cep170-like protein 1 0 S(0.368)S(0.368)PVNNHHS(0.235)PGQT(0.015)PT(0.015)LGQPEAR 56.247 0.0065822 3794100 763.86 593.57 679.5 685.18 675.36 830.4 631.05 309.21 795.14 437.67 TRUE FALSE FALSE 703.399675 644.8755459 704.6828677 682.3449067 667.3067731 658.1656795 648.7555646 403.4867056 707.9151313 452.8789999 1.55317353 1.423946675 1.556006942 1.506682595 1.473476962 1.453292556 1.432514126 0.890937106 1.563144088 1 8.822981833 -9.3723355 1.058876687 0.996291932 1.433102911 0 0.25028183 0.387576675 0.766995127 0.127566334 0.031839571 4.24E-10 9.3723355 0.436810979 S(ph)SPVVNDGVVR ddPTM_HeLa_Curcumin_4h_R1 1 SSPVVNDGVVR 11 0 H0YAM1;H0Y8R1;F5H5I6;H0YAK1;Q12849-5;Q12849 H0YAM1 GRSF1 G-rich sequence factor 1 1 0 S(0.905)S(0.095)PVVNDGVVR 164.92 0.00027194 15718000 1946.8 1500 1740.2 2044.3 2115.1 2949.2 2360 1983.5 2572.7 1790.6 TRUE FALSE FALSE 1792.708726 1629.653316 1804.693343 2035.841228 2089.878814 2337.502676 2426.215248 2588.260019 2290.481247 1852.823217 0.967555193 0.879551433 0.974023494 1.098777914 1.127942912 1.261589694 1.309469369 1.39692767 1.236211434 1 10.85550952 -5.348955596 1.003174671 0.974265086 1.38529588 0.677991116 0.092051971 0.119393224 0.20630918 0.007204011 0.034752352 4.48E-06 5.348955596 0.411030794 S(ph)SPYGTLKPEEMSGPGLAEPK ddPTM_HeLa_Curcumin_4h_R1 1 SSPYGTLKPEEMSGPGLAEPK 21 1 Q5JSZ5;Q5JSZ5-5;A0A494C0D3;H0Y412;A0A494C065 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 S(0.439)S(0.439)PY(0.055)GT(0.067)LKPEEMSGPGLAEPK 91.589 0.0001873 26903000 1414 888.19 941.43 1074.4 1325.4 1194.6 773.51 464.68 1532.6 1106.9 TRUE FALSE FALSE 1302.080408 964.9611859 976.320224 1069.954417 1309.595471 946.8264941 795.2126088 606.3587929 1364.477614 1145.364693 1.13682604 0.84249252 0.852409918 0.934160468 1.143387324 0.826659404 0.694287692 0.529402379 1.191304065 1 10.16159132 -4.001498482 0.674325143 1.038082793 5.94E-13 0.648607252 0.118509628 1.835235697 0.456497683 0.020852384 1.577440021 9.97E-05 4.001498482 -1.038082793 S(ph)SRGQEEISGALPVASPASSR ddPTM_HeLa_Curcumin_4h_R1 4 SSRGQEEISGALPVASPASSR 21 1 Q9UBK8;Q9UBK8-1;H0Y9D5;H0Y8S9 Q9UBK8 MTRR Methionine synthase reductase 1 0 S(0.5)S(0.5)RGQEEIS(0.001)GALPVASPASSR;S(0.5)S(0.5)RGQEEIS(0.001)GALPVASPASSR;S(0.5)S(0.5)RGQEEIS(0.001)GALPVASPASSR;S(0.5)S(0.5)RGQEEISGALPVASPASSR ;;; 238.72 1.47E-36 309795000 11759 10452.5 10519.8 10328.6 11768.2 12526.5 10003.1 5559.12 12960.6 11743.3 TRUE FALSE FALSE 10828.26274 11355.96752 10909.67304 10285.86299 11627.8719 9928.362697 10283.76006 7254.070097 11538.85461 12151.3788 0.891113915 0.93454148 0.897813591 0.846477026 0.956917901 0.817056472 0.846303965 0.596975061 0.949592206 1 13.5688324 -3.500321032 0.654626218 0.941403256 2.24E-39 0.791182174 0.04889743 2.696994043 0.393093971 0.009546399 2.393623182 0.000315994 3.500321032 -0.941403256 S(ph)SS(ph)PVTELASR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPVTELASR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(0.997)S(0.304)S(0.555)PVT(0.144)ELASR 116.24 0.011192 166500000 2326.6 2188.6 2051.3 1989.9 2526.1 2170.8 1762.5 1561.4 2156.6 1702.8 TRUE FALSE FALSE 2142.447155 2377.772832 2127.322983 1981.666321 2495.977907 1720.55161 1811.951006 2037.463672 1920.026376 1761.972173 1.215936998 1.34949511 1.207353337 1.124686503 1.41658191 0.976491931 1.02836528 1.156354058 1.089703007 1 10.78297542 -3.14999272 11.00624425 1.136997257 1.144112697 0 0.13913967 0 0 0.01997077 0 0.000707958 3.14999272 0.00711544 S(ph)SSDPPAVHPPLPPLR ddPTM_HeLa_Curcumin_4h_R1 2 SSSDPPAVHPPLPPLR 16 0 O43150 O43150 ASAP2 "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2" 1 0 S(0.621)S(0.042)S(0.337)DPPAVHPPLPPLR;S(0.465)S(0.071)S(0.465)DPPAVHPPLPPLR ; 137.73 0.00019447 16610700 11330.9 9473.2 8875.2 10772.1 10316 12321.6 9803.9 5843.7 11820.7 10100.5 TRUE FALSE FALSE 10434.04731 10292.0212 9204.122719 10727.5279 10192.98844 9765.961267 10078.97105 7625.417229 10523.99878 10451.49162 0.998330926 0.98474185 0.88065159 1.026411185 0.975266384 0.934408371 0.964357186 0.729600855 1.006937494 1 13.35142124 -3.661456416 1.346529388 0.988253987 1.43E-12 0.757871012 0.041050217 1.922525737 0.962585773 0.005828479 3.869453924 0.000218044 3.661456416 -0.988253987 S(ph)SSEDAESLAPR ddPTM_HeLa_Curcumin_4h_R1 1 SSSEDAESLAPR 12 0 Q4G0J3-3;Q4G0J3;H0YA82 Q4G0J3-3 LARP7 La-related protein 7 1 0 S(0.794)S(0.046)S(0.16)EDAESLAPR 89.663 0.015458 5724800 1441 1189.9 1036.6 1239.5 1204.1 1426.7 1259.9 923.85 1300.8 1214 TRUE FALSE FALSE 1326.943329 1292.749654 1075.017308 1234.371277 1189.741894 1130.786338 1295.249403 1205.527612 1158.105494 1256.18641 1.056326767 1.029106543 0.855778489 0.982633842 0.947106166 0.900173994 1.031096494 0.959672548 0.921921687 1 10.29483485 -6.893106183 22.57015924 1.02754446 0.948964211 0.130365344 0.056398854 3.676657288 762.6303772 0.007430528 0.009765633 1.28E-07 6.893106183 -0.078580249 KSDASDMNSDTS(ph)PSCR ddPTM_HeLa_Curcumin_4h_R1 3 KSDASDMNSDTSPSCR 16 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 0 KSDASDMNS(0.004)DT(0.205)S(0.734)PS(0.058)CR;KSDASDMNS(0.017)DT(0.238)S(0.697)PS(0.048)CR;KSDASDMNS(0.002)DT(0.056)S(0.744)PS(0.198)CR ;; 128.74 0.00022308 47900000 17334.6 15160.7 15533.7 16082.2 16306 19182.6 12044.5 5298.2 18169.4 15633.8 TRUE FALSE FALSE 15962.54812 16471.12335 16109.39259 16015.65612 16111.5616 15203.91253 12382.43625 6913.59679 16176.26228 16177.07339 0.986738932 1.018176957 0.995816252 0.99002185 0.995950331 0.939843207 0.765431173 0.427370058 0.999949861 1 13.98166301 -4.248042308 1.424602924 0.996296633 0.17643108 0.997247155 0.009232243 0.047651833 0.082997214 0.001509038 0.056050961 5.65E-05 4.248042308 -0.819865553 down S(ph)SSFSDTLEESSPIAAIFDTENLEK ddPTM_HeLa_Curcumin_4h_R1 2 SSSFSDTLEESSPIAAIFDTENLEK 25 0 P15924-2;P15924-3;P15924 P15924-2 DSP Desmoplakin 1 0 S(0.229)S(0.229)S(0.229)FS(0.143)DT(0.122)LEES(0.023)S(0.023)PIAAIFDTENLEK;S(0.319)S(0.319)S(0.265)FS(0.082)DT(0.015)LEESSPIAAIFDTENLEK ; 81.406 6.59E-05 4091330 1171.1 1025.4 970.93 980.5 913.6 1888.9 1099.4 1007.3 1328.7 1101.1 TRUE FALSE FALSE 1078.406199 1114.031007 1006.91352 976.4429508 902.7059167 1497.120848 1130.246205 1314.421133 1182.944934 1139.363143 0.946499109 0.977766407 0.883751178 0.857007669 0.792289905 1.313997962 0.991998216 1.153645474 1.03825101 1 10.15401193 -5.265375793 24.99984113 0.947845285 1.137092313 0.505025367 0.100483505 230.7437382 1465440.894 0.013788913 0.031935497 5.43E-06 5.265375793 0.189247029 S(ph)SSPAGETEGDREPQAR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPAGETEGDREPQAR 17 1 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 0 S(0.619)S(0.162)S(0.219)PAGETEGDREPQAR 132.62 0.00015137 33088000 2047 1678.3 1959.3 2282 2634.7 1984.7 1928 1173.6 1775.2 1738.9 TRUE FALSE FALSE 1884.97779 1823.364774 2031.913382 2272.557689 2603.282923 1573.050848 1982.094491 1531.425237 1580.465001 1799.326646 1.047601776 1.013359513 1.129263209 1.263004521 1.446809522 0.87424418 1.10157569 0.851110187 0.878364696 1 10.8132414 -6.760816059 24.9619347 1.022422759 1.121984364 0.101231839 0.168103307 34.36085265 1375992.379 0.025861694 0.035326279 1.73E-07 6.760816059 0.099561604 ATSVDYS(ph)SFADR ddPTM_HeLa_Curcumin_4h_R1 1 ATSVDYSSFADR 12 0 Q86YS7-3;Q86YS7-2;Q86YS7-4 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 0 AT(0.317)S(0.317)VDYS(0.364)S(0.001)FADR 207.34 4.01E-09 6328000 1737.4 1669.3 1459.3 1940.5 1715.9 2238.8 2095.2 3353.3 1952.4 1516.5 TRUE FALSE FALSE 1599.882957 1813.586854 1513.382942 1932.470725 1695.439013 1774.447644 2153.985673 4375.705733 1738.226605 1569.198262 1.019554377 1.155741054 0.964430677 1.231501953 1.080449204 1.130798884 1.372666364 2.788497693 1.107716371 1 10.61581193 -4.144353159 1.93224931 1.040872977 3.721185407 0.972854434 0.084642901 0.120709261 0.362308344 0.012091093 0.636447177 7.17E-05 4.144353159 2.68031243 up S(ph)SSPGKPQAVSSLNSSHSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPGKPQAVSSLNSSHSR 19 1 Q9UHB7;Q9UHB7-2;Q9UHB7-3 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 0 S(0.333)S(0.333)S(0.333)PGKPQAVSSLNSSHSR 127.49 5.02E-05 19273000 3288.8 2349 1704.8 1907.6 4339.4 8924.9 3612 2681.1 4758.7 2664.1 TRUE FALSE FALSE 3028.48801 2552.037093 1767.981388 1899.706857 4287.655489 7073.775136 3713.342999 3498.555048 4236.682516 2756.677277 1.098600854 0.925765636 0.641345072 0.689129218 1.555370854 2.566051237 1.347035807 1.269120284 1.536880124 1 11.42871467 -5.618800081 6.166953964 0.983006902 1.747642139 0.430510011 0.398695679 0.132709534 7.144511558 0.052520474 0.105896341 2.41E-06 5.618800081 0.764635237 S(ph)SSPHDKNLPQK ddPTM_HeLa_Curcumin_4h_R1 1 SSSPHDKNLPQK 12 1 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 0 S(0.333)S(0.333)S(0.333)PHDKNLPQK 71.513 0.015372 21535000 3616.6 3126.1 2570.8 2924.2 3729.9 6073.5 2865.8 2188 5352.6 3564.3 TRUE FALSE FALSE 3330.342294 3396.306154 2666.07611 2912.100435 3685.423379 4813.787638 2946.206635 2855.111128 4765.433172 3688.15916 0.90298226 0.920867568 0.722874473 0.78958101 0.999258226 1.305200624 0.798828496 0.774129045 1.292089892 1 11.8486852 -4.559142428 24.99999002 0.948338549 0.780300237 0.137632015 0.181566842 199.4039287 137467.6435 0.020643518 0.077241425 2.76E-05 4.559142428 -0.168038313 S(ph)SSPTAGPSTEGAEGPEEK ddPTM_HeLa_Curcumin_4h_R1 1 SSSPTAGPSTEGAEGPEEK 19 0 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;A0A0C4DGG3 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 0 S(0.219)S(0.219)S(0.219)PT(0.219)AGPS(0.062)T(0.062)EGAEGPEEK 62.237 0.019103 12400000 6558.9 6198.9 6469.1 6353.6 7094.6 6811.7 5109.3 4927.2 5980.7 5524.7 TRUE FALSE FALSE 6039.756144 6734.705294 6708.850537 6327.310487 7010.001529 5398.876636 5252.653207 6429.480598 5324.632173 5716.682914 1.056514107 1.178079211 1.173556525 1.106815015 1.226235849 0.944407223 0.918828853 1.124687287 0.93141989 1 12.48096256 -3.89329643 20.1632258 1.05376825 11.17699558 0.030899653 0.105070281 1826.194431 348885.8098 0.014126563 9381.954612 0.000127851 3.89329643 10.12322732 S(ph)SSPVGLAK ddPTM_HeLa_Curcumin_4h_R1 1 SSSPVGLAK 9 0 B1AKL4;Q9NRA8;Q9NRA8-3;Q9NRA8-2 B1AKL4 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 0 S(0.333)S(0.333)S(0.333)PVGLAK 128.91 0.0040908 211770000 13692 10973 11688 11377 10926 12994 9506.4 5594.8 12828 10716 TRUE FALSE FALSE 12608.26375 11921.45723 12121.16756 11329.92499 10795.71459 10298.89793 9773.123999 7300.628765 11420.80049 11088.3802 1.137069935 1.075130633 1.093141409 1.021783595 0.973606098 0.928800938 0.88138428 0.658403539 1.029979157 1 13.43676101 -3.643618461 0.648318916 1.068189056 5.00E-11 0.901612387 0.040532058 1.747052734 0.289087235 0.009695627 1.663193099 0.000227186 3.643618461 -1.068189056 S(ph)SSPVTELASR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPVTELASR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.333)S(0.333)S(0.333)PVTELASR 196.67 1.59E-05 284260000 3150.2 2891.1 3399.3 3294.8 3649 3777.2 3479 2818.1 2795.6 2792.8 TRUE FALSE FALSE 2900.858346 3140.993802 3525.281048 3281.166991 3605.488058 2993.766142 3576.611377 3677.325717 2488.929674 2889.849592 1.003809456 1.086905633 1.21988392 1.135410991 1.247638655 1.035959155 1.237646204 1.27249727 0.861266165 1 11.49677869 -7.010192178 2.921290582 1.001813204 1.186557876 0.63480519 0.077772062 0.115146092 1.996559278 0.010219521 0.013207255 9.77E-08 7.010192178 0.184744671 S(ph)SSVGS(ph)SSSYPISPAVSR ddPTM_HeLa_Curcumin_4h_R1 2 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 S(0.94)S(0.05)S(0.009)VGS(0.621)S(0.378)S(0.001)SYPISPAVSR;S(0.583)S(0.026)S(0.391)VGS(0.987)S(0.012)S(0.001)SYPISPAVSR ; 212.35 6.65E-13 716340000 10579.3 9285 9711.1 10980 9448 12775.7 9044.7 5529.5 11122.9 10123.3 TRUE FALSE FALSE 9741.937242 10087.55403 10071.00191 10934.56767 9335.338771 10125.87581 9298.469939 7215.419095 9902.745698 10475.08392 0.930010424 0.963004602 0.961424461 1.043864446 0.891194652 0.966662977 0.887674983 0.688817307 0.945361944 1 13.35467418 -4.00708939 1.403538892 0.967277256 0.411904758 0.822877379 0.038328276 0.688354352 0.75747717 0.005784282 0.636389118 9.84E-05 4.00708939 -0.555372498 S(ph)SSVGSSSS(ph)YPISPAVSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 S(0.94)S(0.042)S(0.018)VGS(0.234)S(0.148)S(0.061)S(0.557)YPISPAVSR 204.81 9.07E-12 292630000 2202 1498.8 1731.3 2219.9 2083.1 2550.1 1870.4 904.24 2342.2 2103.5 TRUE FALSE FALSE 2027.709376 1628.349593 1795.463501 2210.714642 2058.260393 2021.180514 1922.87839 1179.938613 2085.26652 2176.596468 0.931596373 0.748117355 0.82489498 1.015675011 0.945632515 0.9285968 0.883433571 0.542102604 0.958040018 1 11.08785825 -4.232476816 2.709291966 0.940814223 0.447581078 0.67016835 0.077648169 0.24428334 2.22463606 0.012153347 0.277395335 5.85E-05 4.232476816 -0.493233145 S(ph)SSVGSSSSYPIS(ph)PAVSR ddPTM_HeLa_Curcumin_4h_R1 3 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 S(0.926)S(0.05)S(0.024)VGSSSS(0.028)YPIS(0.972)PAVSR;S(0.799)S(0.173)S(0.028)VGSSSSYPIS(1)PAVSR;S(0.988)S(0.008)S(0.004)VGSSSSYPIS(0.968)PAVS(0.032)R ;; 253.52 1.56E-41 275469200 8150.9 6994.4 7090.6 7773.5 7537.9 10382.7 9805.5 7680.6 8582.3 6658.5 TRUE FALSE FALSE 7505.747664 7598.96477 7353.383874 7741.335317 7448.015466 8229.210983 10080.61594 10022.37958 7640.843162 6889.882379 1.089386908 1.102916472 1.067272773 1.123580185 1.081007636 1.194390634 1.463104214 1.454651768 1.108994717 1 12.75026364 -4.900817829 2.092061218 1.057083832 1.480931327 0.930482873 0.040138668 0.063447188 0.532845216 0.006939115 0.031283937 1.26E-05 4.900817829 0.423847495 S(ph)SSVLSLEGSEK ddPTM_HeLa_Curcumin_4h_R1 1 SSSVLSLEGSEK 12 0 A1L390-3;A1L390;A0A0U1RR71;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 0 S(0.987)S(0.007)S(0.007)VLSLEGSEK 181.98 7.94E-05 35665000 4639.5 4025 3641.3 3607.5 3655.7 4630.5 3166.4 2449.6 4395.4 3436.2 TRUE FALSE FALSE 4272.278679 4372.903065 3776.249781 3592.573121 3612.108165 3670.082104 3255.240662 3196.471763 3913.235617 3555.607694 1.201560759 1.229860952 1.062054677 1.010396374 1.015890524 1.032195455 0.915523011 0.898994501 1.100581378 1 11.79588044 -5.106250814 0.83627734 1.104195046 0.879539808 0.560966695 0.067685888 0.784019164 0.772765938 0.015622256 0.12432745 7.83E-06 5.106250814 -0.224655238 S(ph)SSVSPSSWK ddPTM_HeLa_Curcumin_4h_R1 1 SSSVSPSSWK 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 S(0.441)S(0.047)S(0.441)VS(0.029)PS(0.029)S(0.014)WK 115.91 0.0052741 18558000 4602.6 3517.2 4057.1 3711.6 4485 6168.2 3183.3 2272.6 5466.1 3537.8 TRUE FALSE FALSE 4238.299353 3821.211096 4207.459695 3696.242383 4431.519304 4888.84579 3272.614831 2965.505278 4866.482506 3660.738287 1.157771745 1.043836187 1.149347308 1.009698616 1.210553434 1.335480826 0.893976727 0.810083936 1.329371871 1 11.83791892 -4.543638363 24.68995073 1.098785096 0.831057 0.455667535 0.122015327 108.1452605 128619.9208 0.014733514 0.05513944 2.86E-05 4.543638363 -0.267728096 S(ph)STDS(ph)LPGPISR ddPTM_HeLa_Curcumin_4h_R1 1 SSTDSLPGPISR 12 0 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 2 0 S(0.937)S(0.062)T(0.001)DS(0.999)LPGPISR 106.55 0.015766 6388800 5492.8 6320.3 5735 5997.3 5710 6092.2 5041.3 3686.6 6172.9 7250.2 TRUE FALSE FALSE 5058.039084 6866.598569 5947.544145 5972.484762 5641.911979 4828.609047 5182.74531 4810.627369 5495.748314 7502.14391 0.674212484 0.915284837 0.792779266 0.796103732 0.752039956 0.643630555 0.690835229 0.641233683 0.732557037 1 12.87308722 -13.52287875 0.253055202 2.726074064 0.702398684 0 0.113333368 24.045351 0.318726322 20.80429428 0.048969287 3.00E-14 13.52287875 -2.023675381 S(ph)STDSLPGPISR ddPTM_HeLa_Curcumin_4h_R1 1 SSTDSLPGPISR 12 0 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 0 S(0.498)S(0.498)T(0.003)DS(0.001)LPGPISR 142.12 0.0010723 6814900 2106.6 1847.8 1943.3 2295.5 2214.9 2419.7 1324.7 850.21 1961.2 2078.1 TRUE FALSE FALSE 1939.860387 2007.515598 2015.320408 2286.001829 2188.488764 1917.826944 1361.867517 1109.435115 1746.061267 2150.31382 0.902128968 0.933591915 0.937221529 1.063101491 1.017753196 0.89188235 0.633334309 0.515941024 0.812002997 1 11.07033151 -4.7232244 2.654512501 0.962283191 0.530311709 0.840718082 0.06567858 0.062448059 0.84978624 0.007863488 0.038564964 1.89E-05 4.7232244 -0.431971482 S(ph)STGPEPPAPTPLLAER ddPTM_HeLa_Curcumin_4h_R1 1 SSTGPEPPAPTPLLAER 17 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.96)S(0.02)T(0.02)GPEPPAPTPLLAER 180.7 7.64E-06 3045700 756.23 953.93 865.01 918.47 855.52 907.8 830.76 807.57 892.32 764.48 TRUE FALSE FALSE 696.3735975 1036.383459 897.0680315 914.6696145 845.3184828 719.512047 854.0688897 1053.794375 794.4347285 791.0456231 0.880320398 1.310143724 1.134028184 1.156279218 1.068609013 0.909570859 1.079670837 1.332153727 1.004284336 1 9.627617093 -7.288320621 24.92435127 0.943484629 1.127674059 0.319056108 0.118409496 604.9697148 560927.7133 0.02090354 0.023907889 5.15E-08 7.288320621 0.18418943 S(ph)STPEEVK ddPTM_HeLa_Curcumin_4h_R1 3 SSTPEEVK 8 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 1 0 S(0.985)S(0.015)TPEEVK;S(0.981)S(0.019)TPEEVK;S(0.99)S(0.01)TPEEVK ;; 132.88 0.0046753 62235000 11262 11410.3 8992.2 10473.3 8959 11235.4 10592.8 9788.2 11433.3 9898.6 TRUE FALSE FALSE 10370.60082 12396.55549 9325.458842 10429.96426 8852.169776 8905.051391 10890.00546 12772.57712 10179.09559 10242.57561 1.012499317 1.210296702 0.910460337 1.018295071 0.864252324 0.869415245 1.063209672 1.247008331 0.993802338 1 13.32229092 -4.3294133 3.693712464 0.996576561 1.258426184 0.409775913 0.093991457 0.178965719 4.152730503 0.012793283 0.111043011 4.68E-05 4.3294133 0.261849623 S(ph)STPPGESYFGVSSLQLK ddPTM_HeLa_Curcumin_4h_R1 1 SSTPPGESYFGVSSLQLK 18 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.333)S(0.333)T(0.333)PPGESYFGVSSLQLK 84.14 0.0087327 0 603.51 1296.7 320.09 502.13 396.36 648.2 495.92 271.64 487.08 562.02 TRUE FALSE FALSE 555.7415467 1408.78097 331.952817 500.0523191 391.6336659 513.7560133 509.8341805 354.4617855 433.6485426 581.5501532 0.955621013 2.422458256 0.57080686 0.859861039 0.673430595 0.883425119 0.876681362 0.60951198 0.745676947 1 9.183759806 DLFAFQES(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 1 DLFAFQESPPR 11 0 E7EX48;P51957-3;P51957;P51957-2 E7EX48 NEK4 Serine/threonine-protein kinase Nek4 1 0 DLFAFQES(1)PPR 131.79 0.0025763 12954000 2253.4 1906.8 2339.7 2314.2 2566.4 2772.8 2057.2 440.21 2627.4 2376 TRUE FALSE FALSE 2075.041012 2071.615295 2426.41134 2304.624454 2535.797356 2197.690024 2114.919495 574.4280025 2339.180793 2458.565823 0.84400466 0.84261128 0.986921447 0.937385703 1.031413246 0.893891066 0.860224882 0.233643532 0.95144119 1 11.26360127 -4.247516554 3.34761876 0.929039061 0.129451996 0.925020844 0.059580107 0.078570876 1.402829031 0.010177494 0.163348461 5.66E-05 4.247516554 -0.799587065 down S(ph)STPSHGQTTATEPTPAQK ddPTM_HeLa_Curcumin_4h_R1 2 SSTPSHGQTTATEPTPAQK 19 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 0 S(0.268)S(0.268)T(0.268)PS(0.196)HGQTTATEPTPAQK;S(0.435)S(0.435)T(0.126)PS(0.003)HGQT(0.001)T(0.001)ATEPTPAQK ; 151.01 2.51E-05 14677300 5173.8 3907 3367.6 3797.4 5742.3 8812.2 4458 2051.56 6338.8 4022.5 TRUE FALSE FALSE 4764.288271 4244.703671 3492.406218 3781.687365 5673.826823 6984.450386 4583.079482 2677.0712 5643.449499 4162.281576 1.144633823 1.019802143 0.839060538 0.908561157 1.36315305 1.678034092 1.101097895 0.643173978 1.355854811 1 12.02315885 -5.763480975 24.99991894 1.036761317 1.223964922 0.064741622 0.273602578 98.94750227 1211662.294 0.038505063 0.07239287 1.72E-06 5.763480975 0.187203605 S(ph)STSGSDFDTK ddPTM_HeLa_Curcumin_4h_R1 1 SSTSGSDFDTK 11 0 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6;A0A096LNW1 P46100-5 ATRX Transcriptional regulator ATRX 1 0 S(0.849)S(0.135)T(0.006)S(0.009)GS(0.001)DFDTK 174.21 0.00021557 25467000 5019.2 3563.5 4441.8 4482.9 5184.9 5144.1 3419.3 2405.7 5080.5 3878 TRUE FALSE FALSE 4621.925024 3871.513061 4606.417015 4464.350948 5123.073454 4077.155674 3515.236355 3139.186856 4523.181861 4012.760211 1.151806931 0.964800501 1.147942257 1.11253868 1.276695637 1.016047673 0.876014556 0.782301132 1.127199639 1 11.97037923 -4.740991239 2.957328597 1.087342913 0.804366579 0.63420335 0.084211158 0.140046408 2.421664002 0.012973503 0.057807339 1.82E-05 4.740991239 -0.282976334 S(ph)EAASPALPVITK ddPTM_HeLa_Curcumin_4h_R1 1 SEAASPALPVITK 13 0 Q99958 Q99958 FOXC2 Forkhead box protein C2 1 0 S(0.632)EAAS(0.368)PALPVITK 155.43 0.0003847 249000000 10817 7531.1 7520.6 9320.2 7817.5 9712.6 8080.5 1669.1 9855.8 7706.4 TRUE FALSE FALSE 9960.823036 8182.054726 7799.320052 9281.635482 7724.281418 7698.097276 8307.217082 2178.000906 8774.643398 7974.196826 1.249131825 1.026066312 0.978069669 1.163958664 0.968659488 0.96537588 1.041762232 0.273131069 1.100379585 1 12.9611235 -4.247350073 3.860052819 1.086261331 0.181675653 0.865299341 0.091900553 0.08743436 2.49477061 0.016308148 0.226035536 5.66E-05 4.247350073 -0.904585678 down S(ph)STVTEAPIAVVTSR ddPTM_HeLa_Curcumin_4h_R1 1 SSTVTEAPIAVVTSR 15 0 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 0 S(0.994)S(0.005)T(0.001)VTEAPIAVVTSR 115.09 0.0016928 15142000 2224.8 2622.9 2331.4 2553.3 2409.3 3017.5 2591.9 2143.9 2813.8 3232.8 TRUE FALSE FALSE 2048.704732 2849.611789 2417.803735 2542.735121 2380.570671 2391.636486 2664.621738 2797.565241 2505.13318 3345.139559 0.61244223 0.851866339 0.722781125 0.760128263 0.711650629 0.714958657 0.796565193 0.836307482 0.748887493 1 11.70785069 -9.518514819 1.257030411 1.000777656 0.736370058 0 0.100594237 0.230438464 0.648775013 0.052390308 0.012438295 3.03E-10 9.518514819 -0.264407598 S(ph)SVGPSKPVSQPR ddPTM_HeLa_Curcumin_4h_R1 1 SSVGPSKPVSQPR 13 1 Q9Y657 Q9Y657 SPIN1 Spindlin-1 1 0 S(0.865)S(0.135)VGPSKPVSQPR 76.358 0.011617 11471000 2033.3 1565.9 1878.1 2484.6 2361.5 4637.7 3706.4 2345.4 2791.1 2115.1 TRUE FALSE FALSE 1872.362159 1701.249418 1947.704038 2474.319384 2333.340655 3675.788742 3810.391609 3060.501663 2484.923313 2188.599568 0.855506959 0.777323291 0.889931656 1.130549151 1.066134111 1.679516343 1.741018168 1.398383564 1.135394226 1 11.0957923 -5.39498986 2.610754684 0.926619453 1.625969262 0.804634408 0.140591319 0.076032561 0.999971917 0.018886859 0.048177337 4.03E-06 5.39498986 0.69934981 S(ph)T(ph)EKQSVK ddPTM_HeLa_Curcumin_4h_R1 2 STEKQSVK 8 1 Q8IY50;Q8IY50-2 Q8IY50 SLC35F3 Putative thiamine transporter SLC35F3 2 0 S(1)T(1)EKQSVK;S(1)T(1)EKQSVK ; 145.34 0.010407 225199000 8178.5 6613 7009.3 7666.5 7504.9 7958.5 6333.4 6841.9 8539.2 7170.2 TRUE FALSE FALSE 7531.163095 7184.598253 7269.070824 7634.778054 7415.408969 6307.817389 6511.098159 8927.963814 7602.471124 7419.363916 1.015068567 0.96835771 0.97974313 1.029034044 0.999466943 0.850183043 0.877581722 1.203332781 1.024679637 1 12.85707979 -5.483638628 24.99843946 1.003584851 0.96004371 0.005940722 0.090058689 1402.077493 893211.2933 0.011906957 0.026620918 3.28E-06 5.483638628 -0.043541141 S(ph)T(ph)GDVPHTSVT(ph)GDS(ph)GS(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 STGDVPHTSVTGDSGSGK 18 0 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 5 0 S(0.993)T(0.994)GDVPHT(0.233)S(0.233)VT(0.798)GDS(0.874)GS(0.874)GK 42.083 0.0095813 0 566.77 458.49 521.12 509.58 421.22 568.51 268.29 446.63 605.11 446.18 TRUE FALSE FALSE 521.9095564 498.1198326 540.4331656 507.471493 416.1972266 450.5946176 275.8174953 582.805431 538.7309469 461.6847218 1.130445804 1.078917731 1.170567576 1.099173243 0.901474983 0.975979053 0.597415254 1.262345067 1.166880604 1 8.850764181 -5.758967211 24.92783943 1.07590595 0.91321693 0.203143434 0.158815012 73.80625787 744200.5193 0.021079862 0.0406333 1.74E-06 5.758967211 -0.16268902 S(ph)T(ph)SLLNS(ph)MT(ph)IIQNPVK ddPTM_HeLa_Curcumin_4h_R1 1 STSLLNSMTIIQNPVK 16 0 F8W9A8;B7WPL9;Q6PFW1-7;Q6PFW1-4;Q6PFW1-3;Q6PFW1-2;Q6PFW1;Q6PFW1-5;Q6PFW1-6 F8W9A8 PPIP5K1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 4 0 S(0.686)T(0.728)S(0.686)LLNS(0.912)MT(0.987)IIQNPVK 55.589 0.0086236 0 301.38 238.4 314.93 196.59 396.85 396.23 433.32 325.66 468.36 499.62 TRUE FALSE FALSE 277.525455 259.0062337 326.6015828 195.7765627 392.1178229 314.0474316 445.477793 424.9522348 416.9820798 516.9817578 0.536818661 0.500996853 0.631746823 0.378691433 0.758475163 0.607463275 0.861689578 0.821986905 0.8065702 1 9.013969564 -9.335343274 1.058500745 1.00001806 0.628809686 0.303889997 0.151006919 0.365362139 0.73263306 0.100474606 0.026424138 4.62E-10 9.335343274 -0.371208375 S(ph)TAALEEDAQILK ddPTM_HeLa_Curcumin_4h_R1 2 STAALEEDAQILK 13 0 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5;Q15052-2;Q15052;Q14155-6;Q14155-2;Q14155-3;Q14155;E9PDQ5 B1ALK7;Q14155-6 ARHGEF7;ARHGEF6 Rho guanine nucleotide exchange factor 7;Rho guanine nucleotide exchange factor 6 1 0 S(0.992)T(0.008)AALEEDAQILK;S(0.981)T(0.019)AALEEDAQILK ; 244.67 4.07E-27 73384000 8830.1 7307.2 8197.2 8801.8 9141.3 15370 12850.7 2533.2 10820.9 8925.8 TRUE FALSE FALSE 8131.188268 7938.801808 8500.995443 8765.380484 9032.295968 12182.08874 13211.25606 3305.561019 9633.874343 9235.970886 0.880382622 0.859552494 0.920422503 0.949048085 0.977947644 1.318983017 1.43041335 0.357900762 1.043081931 1 13.17304791 -5.506033443 24.00822772 0.934818523 1.08743627 0.012534346 0.269903092 968.8090217 1380761.003 0.035374435 0.077221821 3.12E-06 5.506033443 0.152617747 S(ph)TDEYS(ph)EADEEEEEEEGKPSR ddPTM_HeLa_Curcumin_4h_R1 3 STDEYSEADEEEEEEEGKPSR 21 1 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 2 0 S(0.584)T(0.241)DEY(0.478)S(0.697)EADEEEEEEEGKPSR;S(0.464)T(0.464)DEY(0.228)S(0.845)EADEEEEEEEGKPSR;S(0.579)T(0.2)DEY(0.557)S(0.664)EADEEEEEEEGKPSR ;; 98.267 0.00016174 12329000 5229.7 3756.8 4316.3 4282.5 4579.9 5386.2 4289.1 4534.5 4469.9 4410.93 TRUE FALSE FALSE 4815.763727 4081.521052 4476.265875 4264.78015 4525.287684 4269.041405 4409.440602 5917.048176 3979.563153 4564.209489 1.055114525 0.894244899 0.980731907 0.934396232 0.991472388 0.935329856 0.966090757 1.296401532 0.871906332 1 12.15614929 -4.257773571 24.77013136 0.997250579 1.296401663 0.697376803 0.06224081 130.3268845 880584.9131 0.00786906 0.0776056 5.52E-05 4.257773571 0.299151084 S(ph)TDSSSVSGSLQQETK ddPTM_HeLa_Curcumin_4h_R1 4 STDSSSVSGSLQQETK 16 0 Q9H8G2;A0A3B3ISJ3 Q9H8G2 CAAP1 Caspase activity and apoptosis inhibitor 1 1 0 S(0.646)T(0.354)DSSSVSGSLQQETK;S(0.988)T(0.012)DSSSVSGSLQQETK;S(0.946)T(0.049)DS(0.004)SSVSGSLQQETK;S(0.857)T(0.122)DS(0.01)S(0.01)S(0.001)VSGSLQQETK ;;; 289.87 1.61E-79 156447000 8012.4 7444.7 7062.5 8422 8257.5 9331.4 9059.6 9433.92 8709.4 7065.3 TRUE FALSE FALSE 7378.210085 8088.186695 7324.242463 8387.151996 8159.034706 7395.962453 9313.787993 12310.27878 7754.00061 7310.818649 1.009218042 1.10633119 1.001836157 1.147224736 1.116022035 1.011646275 1.273973332 1.683844091 1.060620018 1 12.83581725 S(ph)TELLLGVK ddPTM_HeLa_Curcumin_4h_R1 2 STELLLGVK 9 0 Q6R327-3;Q6R327 Q6R327-3 RICTOR Rapamycin-insensitive companion of mTOR 1 0 S(0.97)T(0.03)ELLLGVK;S(0.989)T(0.011)ELLLGVK ; 149.33 0.0017445 4811200 3690.7 2855.1 3467.4 2930.8 3734.8 3054.3 2297.23 1873.51 3235 2980 TRUE FALSE FALSE 3398.577201 3101.882122 3595.904894 2918.673126 3690.264949 2420.803751 2361.684091 2444.734574 2880.128594 3083.554778 1.102162097 1.005943577 1.166155672 0.94652871 1.196756735 0.785069157 0.76589659 0.792829948 0.934028678 1 11.59037876 -5.240127174 24.03475358 1.055840376 0.779728269 0.693753008 0.081828514 172.8514982 194931.8647 0.009679489 0.02464562 5.75E-06 5.240127174 -0.276112108 AQPGSPES(ph)SGQPK ddPTM_HeLa_Curcumin_4h_R1 2 AQPGSPESSGQPK 13 0 Q05GC8;Q96PN7-2;Q96PN7-3;Q96PN7-4;Q96PN7-5;Q96PN7 Q05GC8 BCAR2;TRERF1 Transcriptional-regulating factor 1 1 0 AQPGS(0.134)PES(0.571)S(0.295)GQPK;AQPGS(0.031)PES(0.941)S(0.028)GQPK ; 134.4 0.0013579 96539000 12804.2 11349.3 11534.7 11812.4 11226.9 14374.6 10712.7 4187.3 12998.4 11020.2 TRUE FALSE FALSE 11790.73406 12330.28292 11962.18613 11763.52342 11093.02655 11393.14592 11013.26953 5463.988494 11572.50804 11403.15113 1.033989107 1.081304876 1.049024607 1.031602869 0.972803607 0.999122593 0.965809311 0.479164788 1.014851764 1 13.47714493 -4.247330714 3.33352863 1.020035849 0.397321107 0.970064112 0.028467138 0.044893115 0.790558683 0.004488815 0.072501533 5.66E-05 4.247330714 -0.622714742 down S(ph)TENVNKLPELSSFGKPSSSVQGTGLIR ddPTM_HeLa_Curcumin_4h_R1 1 STENVNKLPELSSFGKPSSSVQGTGLIR 28 2 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 0 S(0.5)T(0.5)ENVNKLPELSSFGKPSSSVQGTGLIR 62.677 0.0012391 22754000 277.54 138.33 264.13 235.9 213.87 242.63 217.26 264.33 340.32 132.51 TRUE FALSE FALSE 255.5724161 150.2866288 273.9188902 234.9239083 211.3197399 192.305803 223.3557309 344.9230002 302.9877474 137.1147126 1.863931384 1.096064937 1.997735217 1.713338443 1.541189387 1.402517639 1.628969835 2.515579791 2.209739142 1 7.099239573 -9.495309073 0.741660585 0.890297163 1.710698443 0 0.519238045 0.864292958 0.657155673 0.46790592 0.068236214 3.20E-10 9.495309073 0.82040128 S(ph)TEPELIQVK ddPTM_HeLa_Curcumin_4h_R1 1 STEPELIQVK 10 0 M0QXM4;Q15758-3;Q15758-2;Q15758 M0QXM4 SLC1A5 Amino acid transporter;Neutral amino acid transporter B(0) 1 0 S(0.979)T(0.021)EPELIQVK 108.56 0.008225 2690800 1476.8 1856.3 1713.1 2424.7 1954.2 3305.1 1336.6 870.59 2722.1 1801.4 TRUE FALSE FALSE 1359.909722 2016.7503 1776.588993 2414.667234 1930.897441 2619.585004 1374.101399 1136.028883 2423.49244 1863.998516 0.729565882 1.081948448 0.953106442 1.295423367 1.03589001 1.405357881 0.737179449 0.609458041 1.300157924 1 10.864185 -10.14895301 3.334187807 1.002212757 0.929592695 0 0.258046179 1.624263166 33.29545571 0.236451723 0.037012266 7.10E-11 10.14895301 -0.072620062 NFELVDSS(ph)PCKK ddPTM_HeLa_Curcumin_4h_R1 1 NFELVDSSPCKK 12 1 A0A087WUU7;Q96GX5-2;Q96GX5-3;Q96GX5 A0A087WUU7 MASTL Serine/threonine-protein kinase greatwall 1 0 NFELVDS(0.428)S(0.572)PCKK 108.36 0.0095584 51886000 6810.7 5487.3 6108.2 5801.2 6199.3 6585.1 4371.7 1558.6 6971.7 6353.2 TRUE FALSE FALSE 6271.625908 5961.597761 6334.575265 5777.196172 6125.377396 5219.276031 4494.358136 2033.809965 6206.921952 6573.973227 0.954008435 0.9068485 0.963583977 0.878798251 0.931761841 0.793930223 0.683659331 0.309373022 0.944165992 1 12.68254987 -4.247042724 0.963212236 0.96609735 1.89E-21 0.959550883 0.039571581 0.273973525 0.188331549 0.006370576 0.276629051 5.66E-05 4.247042724 -0.96609735 down S(ph)TFSTNYR ddPTM_HeLa_Curcumin_4h_R1 2 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 S(0.897)T(0.017)FS(0.061)T(0.025)NYR;S(0.899)T(0.015)FS(0.074)T(0.012)NYR ; 117.71 0.0089912 321129000 1822.59 1439.05 1968.65 2470.2 1408.21 3062.8 2142.93 572.08 2209.13 2409.34 TRUE FALSE FALSE 1678.330078 1563.43507 2041.609901 2459.978967 1391.418015 2427.540755 2203.054848 746.5045585 1966.793966 2493.064386 0.673199653 0.627113796 0.818915834 0.986729016 0.558115556 0.973717634 0.883673467 0.299432523 0.788906206 1 11.28370443 -9.350568508 1.040280494 1.002105941 0.739261211 0.056807685 0.206554948 0.681014954 1.302668346 0.13271793 0.03358269 4.46E-10 9.350568508 -0.262844731 S(ph)TGDIAGTVVPETNKEPR ddPTM_HeLa_Curcumin_4h_R1 1 STGDIAGTVVPETNKEPR 18 1 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;A0A3B3IRI3;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISZ5;Q9UDY2-5;A0A3B3IRV6;A0A3B3ISF1;A0A3B3IS03;A0A3B3IT83 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 S(0.972)T(0.028)GDIAGTVVPETNKEPR 165.49 7.53E-06 5995400 545.52 567.27 574.25 568.06 709.48 1024.7 597.92 750.52 678.4 821.71 TRUE FALSE FALSE 502.3415164 616.3022911 595.5322102 565.7095182 701.0199144 812.1656693 614.696026 979.350093 603.9812173 850.2643613 0.590806271 0.724836085 0.700408293 0.665333682 0.824472889 0.955191945 0.722946949 1.151818349 0.710345211 1 9.731767659 -4.254914547 24.09344437 0.788072087 1.151818628 0.463283585 0.122520416 440.9916094 1628319.514 0.022782769 0.284947217 5.56E-05 4.254914547 0.363746541 S(ph)TGSMSVVSAALVAEPVQNGSR ddPTM_HeLa_Curcumin_4h_R1 2 STGSMSVVSAALVAEPVQNGSR 22 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 0 S(0.476)T(0.476)GS(0.04)MS(0.009)VVSAALVAEPVQNGSR;S(0.808)T(0.191)GS(0.001)MSVVSAALVAEPVQNGSR ; 127.01 5.28E-05 7978600 1266.46 1092.6 1067.23 1040.53 1156.85 1503.27 1021.96 537.69 1344.47 1298.96 TRUE FALSE FALSE 1166.218355 1187.039475 1106.782483 1036.224563 1143.055319 1191.474857 1050.633447 701.6292058 1196.985005 1344.098763 0.867658231 0.883148998 0.823438361 0.770943766 0.850425096 0.88644889 0.781663875 0.522007181 0.890548401 1 10.39242343 -1.904996443 0.149251636 1.024166094 5.16E-21 0.565572181 0.078288209 26.65196058 0.330238192 0.182946764 5.656230326 0.012445248 1.904996443 -1.024166094 S(ph)TGVVNIPAAECLDEYEDDEAGQKER ddPTM_HeLa_Curcumin_4h_R1 1 STGVVNIPAAECLDEYEDDEAGQKER 26 1 Q96IZ0;H0YI16 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 1 0 S(0.828)T(0.172)GVVNIPAAECLDEYEDDEAGQKER 115.54 5.25E-09 14466000 1461.6 1340.1 1321.9 1449.7 1298.3 1911.6 1630.9 756.23 1355.5 1137.5 TRUE FALSE FALSE 1345.912818 1455.932273 1370.890777 1443.701526 1282.81862 1515.112612 1676.658665 986.8010457 1206.805041 1177.02804 1.143484073 1.236956319 1.164705283 1.226565108 1.089879405 1.287235784 1.424484895 0.838383634 1.025298464 1 10.20093297 -8.554865681 0.638459809 1.000649654 1.194309629 0.167406418 0.143181729 0.852196483 0.705316601 0.080438667 0.032768603 2.79E-09 8.554865681 0.193659975 S(ph)TNTAVSR ddPTM_HeLa_Curcumin_4h_R1 1 STNTAVSR 8 0 Q9NWB6-2;Q9NWB6 Q9NWB6-2 ARGLU1 Arginine and glutamate-rich protein 1 1 0 S(0.982)T(0.018)NTAVSR 103.31 0.013249 2401400 719.15 1598.4 686.22 445.72 721 413.67 379.02 299.33 536.58 425.61 TRUE FALSE FALSE 662.2285187 1736.558574 711.6519169 443.8757287 712.4025459 327.870179 389.6542811 390.5943391 477.7185165 440.3999158 1.503698105 3.943140113 1.615922009 1.007892401 1.617626435 0.744482838 0.884773741 0.886908296 1.084737983 1 8.782670383 -6.255897369 23.38393836 1.51561119 1.03732963 0.140082032 0.826067649 467.0966984 1970856.692 0.13713598 0.222981253 5.55E-07 6.255897369 -0.47828156 S(ph)TPAEDDSRDSQVK ddPTM_HeLa_Curcumin_4h_R1 1 STPAEDDSRDSQVK 14 1 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 1 0 S(0.774)T(0.226)PAEDDSRDSQVK 71.781 0.01329 7736600 2121.8 2164.6 1646.6 1950.3 1916.8 3071.1 2672.6 2327.2 2251.7 2084.3 TRUE FALSE FALSE 1953.857291 2351.698379 1707.624444 1942.230175 1893.943412 2434.119242 2747.585963 3036.752567 2004.694143 2156.72927 0.905935352 1.090400363 0.791765786 0.900544265 0.87815538 1.128616037 1.273959602 1.408036052 0.929506624 1 11.07462937 -4.842896921 2.05027504 0.943915769 1.383537352 0.816528428 0.078836851 0.108179104 0.860559764 0.011531025 0.05739705 1.44E-05 4.842896921 0.439621582 S(ph)TPKEDDSSASTSQSTR ddPTM_HeLa_Curcumin_4h_R1 2 STPKEDDSSASTSQSTR 17 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 S(0.498)T(0.498)PKEDDS(0.001)SASTS(0.001)QS(0.001)TR;S(0.958)T(0.042)PKEDDSSASTSQSTR ; 145.79 0.0026451 76435000 6253.8 5056.5 5159.3 5656.4 6035.1 10672 9690.5 2857.5 5956.8 4233.1 TRUE FALSE FALSE 5758.805131 5493.561329 5350.508197 5632.995316 5963.135374 8458.506902 9962.389349 3728.738596 5303.353943 4380.19991 1.314735685 1.254180504 1.221521462 1.286013294 1.361384297 1.931077822 2.274414309 0.851271328 1.210756142 1 12.096781 -5.485784055 3.435744173 1.177157678 1.741211188 0.260949762 0.344918366 0.198625472 4.78297715 0.047952264 0.109893866 3.27E-06 5.485784055 0.56405351 S(ph)TPLEENVVDREQIDFLAAR ddPTM_HeLa_Curcumin_4h_R1 2 STPLEENVVDREQIDFLAAR 20 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 S(0.5)T(0.5)PLEENVVDREQIDFLAAR;S(0.5)T(0.5)PLEENVVDREQIDFLAAR ; 102.9 0.00017146 10025300 1408.78 1484.47 1718.76 1501.47 1651.76 1931.2 1333.06 2573.8 1835.98 1492.06 TRUE FALSE FALSE 1297.273576 1612.780972 1782.458758 1495.257315 1632.063841 1530.647351 1370.462076 3358.539772 1634.577587 1543.908974 0.84025263 1.044608846 1.154510264 0.968488 1.057098487 0.99141036 0.887657303 2.175348306 1.058726657 1 10.59237198 -4.259342386 24.99895916 0.960866376 2.175348722 0.934741513 0.092616286 34.86545364 415612.7598 0.014358733 0.12632525 5.50E-05 4.259342386 1.214482346 S(ph)TPLSQPSANGVQTEGLDYDR ddPTM_HeLa_Curcumin_4h_R1 5 STPLSQPSANGVQTEGLDYDR 21 0 A0A0U1RRM6;Q8N8S7-3;Q8N8S7-2;Q8N8S7 A0A0U1RRM6 ENAH Protein enabled homolog 1 0 S(0.855)T(0.145)PLSQPSANGVQTEGLDYDR;S(0.854)T(0.146)PLSQPSANGVQTEGLDYDR;S(0.595)T(0.152)PLS(0.087)QPS(0.028)ANGVQT(0.138)EGLDYDR;S(0.827)T(0.171)PLS(0.002)QPSANGVQTEGLDYDR;S(0.785)T(0.175)PLS(0.04)QPS(0.001)ANGVQTEGLDYDR ;;;; 280.01 3.86E-73 120550500 5855.4 5661.92 6019.84 6151.04 6736.31 8245.5 7043.72 2811.09 6776.4 4864.13 TRUE FALSE FALSE 5391.938911 6151.311136 6242.940566 6125.588626 6655.983903 6535.290354 7241.347826 3668.1784 6033.045874 5033.158155 1.071283426 1.222157331 1.240362487 1.21704672 1.322426933 1.298447248 1.438728449 0.728802531 1.198660103 1 12.29724822 -7.373629381 2.078037015 1.026838375 1.230156414 0.045608053 0.184277593 0.339864541 2.790986039 0.030345 0.034525918 4.23E-08 7.373629381 0.203318039 S(ph)TPPLYR ddPTM_HeLa_Curcumin_4h_R1 1 STPPLYR 7 0 Q99958 Q99958 FOXC2 Forkhead box protein C2 1 0 S(0.999)T(0.001)PPLYR 101.6 0.018763 24235000 4562.8 3900.8 4384.9 4760.1 5291.2 5479.2 4659.2 1398.9 4161 3649.6 TRUE FALSE FALSE 4201.649565 4237.96777 4547.408251 4740.403967 5228.105896 4342.752157 4789.924612 1825.41817 3704.54871 3776.423328 1.112600257 1.122217347 1.204157441 1.255262865 1.384406737 1.149964339 1.268375973 0.483372231 0.980967542 1 11.88280478 -4.253245438 24.822079 1.121599458 0.483371883 0.726713198 0.122777227 449.3943232 1361325.527 0.019386377 0.290240445 5.58E-05 4.253245438 -0.638227575 S(ph)TPPPNNLVNPVQELETER ddPTM_HeLa_Curcumin_4h_R1 3 STPPPNNLVNPVQELETER 19 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 0 S(0.564)T(0.436)PPPNNLVNPVQELETER;S(0.593)T(0.407)PPPNNLVNPVQELETER;S(0.803)T(0.197)PPPNNLVNPVQELETER ;; 102.84 0.00076077 18240400 4245.56 3548.94 3617.37 3401.11 3669.97 5369 4106.72 3015.89 3805.59 3586.58 TRUE FALSE FALSE 3909.519446 3855.69456 3751.432914 3387.037108 3626.208005 4255.408879 4221.943511 3935.420978 3388.126298 3711.213388 1.053434292 1.038930979 1.010837298 0.912649518 0.977094989 1.146635462 1.137618097 1.060413554 0.912943004 1 11.85767524 -5.258820104 24.91677432 1.014284103 1.117161946 0.502946456 0.053708739 144.2297063 1372023.689 0.006878084 0.01666257 5.51E-06 5.258820104 0.102877843 S(ph)TPPPNNLVNPVQELETERR ddPTM_HeLa_Curcumin_4h_R1 2 STPPPNNLVNPVQELETERR 20 1 Q8NDI1-3;Q8NDI1-2;Q8NDI1 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 0 S(0.875)T(0.125)PPPNNLVNPVQELETERR;S(0.5)T(0.5)PPPNNLVNPVQELETERR ; 121.63 4.93E-05 29657700 3206.4 2488.4 2701.6 2808 2674.6 3072.1 2686.7 2028.61 3086.5 2510 TRUE FALSE FALSE 2952.610057 2703.486208 2801.723673 2796.38124 2642.707142 2434.91183 2762.081571 2647.12385 2747.918672 2597.222313 1.136833779 1.040914439 1.078738489 1.076681509 1.017512875 0.937506126 1.06347522 1.019213425 1.058022125 1 11.34275379 -5.691342453 5.827160184 1.066049838 1.007208635 0.287943344 0.043076028 0.26932083 16.38228932 0.008339793 0.016757062 2.04E-06 5.691342453 -0.058841204 S(ph)TPQPPSGK ddPTM_HeLa_Curcumin_4h_R1 2 STPQPPSGK 9 0 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 0 S(0.878)T(0.122)PQPPSGK;S(0.982)T(0.018)PQPPSGK ; 123.62 0.0021339 14435000 14201.1 12647.5 14665 13747.2 14424.8 13186.5 10806.3 4537.5 13625.1 10914.3 TRUE FALSE FALSE 13077.06795 13740.69354 15208.4978 13690.31773 14252.79368 10451.47126 11109.49569 5920.962862 12130.46062 11293.57111 1.157921424 1.216682784 1.346650909 1.21222221 1.262027178 0.925435467 0.983700867 0.52427729 1.074103178 1 13.46321413 -4.032973309 1.301273814 1.125172391 9.77E-12 0.732004255 0.115056032 1.103007597 1.088556239 0.020035125 1.890594963 9.27E-05 4.032973309 -1.125172391 S(ph)TPS(ph)PTPVESSDPK ddPTM_HeLa_Curcumin_4h_R1 1 STPSPTPVESSDPK 14 0 Q9NW07 Q9NW07 ZNF358 Zinc finger protein 358 2 0 S(0.809)T(0.193)PS(0.861)PT(0.137)PVESSDPK 151.07 0.0011582 15272000 7100.4 5787.6 5712.3 5539.9 5883.4 5727.5 4380.2 4032.3 6534.9 5082.8 TRUE FALSE FALSE 6538.395848 6287.854355 5924.002863 5516.977362 5813.244298 4539.551938 4503.096623 5261.729708 5818.03782 5259.426922 1.24317648 1.195539828 1.126359003 1.048969297 1.105299947 0.863126726 0.856195302 1.00043784 1.106211362 1 12.36068989 -5.272154167 19.74368537 1.118779903 0.90154752 0.634201947 0.073524269 26.11082374 48115.0214 0.014602475 0.03314981 5.34E-06 5.272154167 -0.217232383 S(ph)TPSPT(ph)PVESSDPK ddPTM_HeLa_Curcumin_4h_R1 1 STPSPTPVESSDPK 14 0 Q9NW07 Q9NW07 ZNF358 Zinc finger protein 358 2 0 S(0.772)T(0.228)PS(0.38)PT(0.62)PVESSDPK 163.62 0.001025 14309000 5790.2 5670.3 5416.1 5488.6 5844.1 5974.8 4931 4019.7 5850.3 5411.2 TRUE FALSE FALSE 5331.89956 6160.415466 5616.82543 5465.889627 5774.412924 4735.55913 5069.350589 5245.288026 5208.536727 5599.238797 0.952254361 1.100223743 1.003140897 0.976184411 1.031285347 0.845750521 0.905364242 0.936785912 0.930222288 1 12.45101499 -5.265602354 24.99888021 0.991396745 0.896906626 0.483117017 0.048405633 238.5793778 1432687.281 0.006708464 0.015517637 5.42E-06 5.265602354 -0.094490118 S(ph)TQGVTLTDLQEAEK ddPTM_HeLa_Curcumin_4h_R1 1 STQGVTLTDLQEAEK 15 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 S(0.5)T(0.5)QGVTLTDLQEAEK 96.096 0.0052999 4132400 1572.8 619.31 1972.4 1825.2 1924.7 2798.1 2615.8 1790.3 1879.1 2459 TRUE FALSE FALSE 1448.31122 672.8403968 2045.498879 1817.647806 1901.74921 2217.742519 2689.192308 2336.154228 1672.967431 2544.450067 0.569204025 0.264434506 0.80390608 0.714357821 0.747410702 0.871599937 1.056885471 0.918137188 0.657496664 1 11.31313816 -5.059536286 3.172771547 0.742739147 0.986886398 0.275664223 0.186436148 0.360119935 7.113754623 0.033354582 0.102238574 8.72E-06 5.059536286 0.244147251 S(ph)TSATDTHHVEMAR ddPTM_HeLa_Curcumin_4h_R1 2 STSATDTHHVEMAR 14 0 H3BQP2;H3BNP3;H3BTL2;H3BS02;O14874-2;O14874-3;O14874 H3BQP2 BCKDK "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial" 1 0 S(0.329)T(0.329)S(0.329)AT(0.014)DT(0.001)HHVEMAR;S(0.807)T(0.166)S(0.021)ATDT(0.005)HHVEMAR ; 119.96 0.00084705 47321000 1230.07 1221.51 1106.87 1165.64 1410.51 1862.38 1122.84 841.76 1439.02 1051.88 TRUE FALSE FALSE 1132.708662 1327.091881 1147.891576 1160.816891 1393.690589 1476.101395 1154.343868 1098.408749 1281.163106 1088.432752 1.04067859 1.219268604 1.054627926 1.066503088 1.280456314 1.356171424 1.060555984 1.00916547 1.17707144 1 10.08803656 -7.407486663 5.489866743 1.017619071 1.152035476 0.027204992 0.115807245 0.244521236 10.09397328 0.018846072 0.021394441 3.91E-08 7.407486663 0.134416406 S(ph)TSDTDLVTSDSR ddPTM_HeLa_Curcumin_4h_R1 1 STSDTDLVTSDSR 13 0 Q76N89-2;Q76N89 Q76N89-2 HECW1 E3 ubiquitin-protein ligase HECW1 1 0 S(0.844)T(0.095)S(0.06)DTDLVTSDSR 144.51 0.00079495 8053000 1533.6 1101.9 1342.3 1560.2 1161.4 1256.7 981.46 954.77 1631.8 1293.8 TRUE FALSE FALSE 1412.213942 1197.143326 1392.046819 1553.744306 1147.551064 996.0462541 1008.997126 1245.874978 1452.795623 1338.759454 1.054867577 0.894218392 1.03980354 1.160585123 0.857174947 0.744006887 0.753680673 0.930618995 1.085180477 1 10.38668105 -5.58959172 7.517475475 1.024915334 0.80326749 0.643946634 0.079435219 0.103518951 9.931462258 0.010894464 0.021881238 2.57E-06 5.58959172 -0.221647843 S(ph)TSFRGGMGSGGLATGIAGGLAGMGGIQNEK ddPTM_HeLa_Curcumin_4h_R1 3 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 S(0.327)T(0.327)S(0.155)FRGGMGS(0.139)GGLAT(0.051)GIAGGLAGMGGIQNEK;S(0.344)T(0.255)S(0.294)FRGGMGS(0.015)GGLAT(0.091)GIAGGLAGMGGIQNEK;S(0.309)T(0.309)S(0.309)FRGGMGS(0.037)GGLAT(0.036)GIAGGLAGMGGIQNEK ;; 76.734 1.04E-05 472086700 4604.7 3622.89 3633.47 3937.5 3397.11 4799.7 3990.86 7408.6 4565.9 3853.21 TRUE FALSE FALSE 4240.233136 3936.036468 3768.129595 3921.207668 3356.601682 3804.188116 4102.832791 9667.448035 4065.032193 3987.108761 1.063485696 0.987190645 0.945078206 0.983471459 0.841863587 0.954121983 1.029024548 2.424676279 1.019543844 1 11.96112724 -4.261508855 6.524933447 1.000315277 2.452678423 0.981614171 0.059254246 0.012574375 3.252357266 0.009648709 0.080307462 5.48E-05 4.261508855 1.452363146 S(ph)TSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDR ddPTM_HeLa_Curcumin_4h_R1 1 STSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDR 40 2 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 S(0.248)T(0.248)S(0.248)FRGGMGS(0.248)GGLAT(0.007)GIAGGLAGMGGIQNEKETMQSLNDR 43.069 0.0049512 54938000 882.61 454.14 513.05 582.4 448.53 996.54 391.98 1531.1 903.76 783.78 TRUE FALSE FALSE 812.7504872 493.393838 532.0640843 579.9901831 443.1815727 789.8463707 402.9779038 1997.925342 804.6197891 811.0162967 1.002138293 0.608364887 0.656046107 0.715139986 0.546452118 0.97389704 0.496880156 2.463483594 0.992112973 1 9.663587094 APSQVSISAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 APSQVSISASPR 12 0 A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-11;Q8IVL1;A0A0A0MTL4;Q8IVL1-4;Q8IVL1-3;Q8IVL1-2;Q8IVL1-5;Q8IVL1-6;Q8IVL1-7 A0A0A0MTE8 NAV2 Neuron navigator 2 1 0 APSQVSISAS(1)PR;APSQVSISAS(1)PR;APSQVSISAS(1)PR ;; 191.01 5.33E-06 83103000 3866.1 3053.03 3309.67 3227.67 3178.49 3759.1 2395.73 768.72 3433.96 3105.52 TRUE FALSE FALSE 3560.094106 3316.920309 3432.329282 3214.314757 3140.588583 2979.420286 2462.947736 1003.099189 3057.263179 3213.436589 1.107877503 1.032203442 1.068117944 1.00027328 0.977330187 0.92717569 0.766452882 0.312157767 0.951399878 1 11.64990129 -4.246938869 1.224418017 1.0454491 6.64E-25 0.953217017 0.04737368 0.214919245 0.259347189 0.007093396 0.286149727 5.66E-05 4.246938869 -1.0454491 down S(ph)TSPIIGSPPVR ddPTM_HeLa_Curcumin_4h_R1 1 STSPIIGSPPVR 12 0 Q86TB9-2;Q86TB9-4;Q86TB9 Q86TB9-2 PATL1 Protein PAT1 homolog 1 1 0 S(0.333)T(0.333)S(0.333)PIIGSPPVR 163.45 0.00013249 18901000 3194.9 2613.4 2665 3278.6 2821.2 3389.6 3494.7 3077.1 2600.1 3003 TRUE FALSE FALSE 2942.020294 2839.290651 2763.767244 3265.034022 2787.559033 2686.558751 3592.751876 4015.293625 2314.875535 3107.354026 0.94679276 0.913732593 0.889427861 1.050744136 0.897084468 0.864580839 1.156209381 1.292190587 0.744966784 1 11.6014709 -4.575127591 4.508455831 0.95818048 1.266100967 0.656534287 0.087489089 0.059877887 2.505780656 0.008111891 0.035348484 2.66E-05 4.575127591 0.307920487 S(ph)TSPVTDPSIPIRK ddPTM_HeLa_Curcumin_4h_R1 1 STSPVTDPSIPIRK 14 1 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 0 S(0.515)T(0.241)S(0.241)PVT(0.003)DPSIPIRK 73.279 0.013204 7657400 5383.2 4294.5 4213.9 4419.9 4421.8 5401.9 3812.7 2616.5 5398 5077.9 TRUE FALSE FALSE 4957.11404 4665.697444 4370.070841 4401.611625 4369.072923 4281.485048 3919.674101 3414.258805 4805.852905 5254.356647 0.943429305 0.887967406 0.831704266 0.837707054 0.831514344 0.814844773 0.745985544 0.649795786 0.914641549 1 12.35929841 -2.356629687 0.181756034 1.031822864 1.35E-17 0.85236676 0.036377015 5.667112942 0.095730168 0.036835292 1.478263072 0.004399166 2.356629687 -1.031822864 TVSLTPSPTTQVET(ph)PDLVDHDNTSPLFR ddPTM_HeLa_Curcumin_4h_R1 2 TVSLTPSPTTQVETPDLVDHDNTSPLFR 28 0 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 0 TVSLTPSPT(0.01)T(0.01)QVET(0.98)PDLVDHDNTSPLFR;TVS(0.001)LT(0.016)PS(0.066)PT(0.298)T(0.298)QVET(0.32)PDLVDHDNTSPLFR ; 130.81 4.40E-10 21816000 3087 2728.5 3107.4 3053.4 3077.4 4428.3 4449.2 5494.1 3477.2 3123.4 TRUE FALSE FALSE 2842.660693 2964.339382 3222.562978 3040.76584 3040.704015 3509.820663 4574.032578 7169.225798 3095.75986 3231.937918 0.879553 0.917201833 0.997099282 0.940849087 0.940829958 1.085980224 1.415260037 2.218243661 0.957864891 1 11.65818377 -4.144334251 1.326458268 0.942085186 3.042210663 0.991401352 0.036046012 0.139861773 0.173851363 0.007268567 0.423944688 7.17E-05 4.144334251 2.100125478 up S(ph)TSSSSDTMSTFKPMVAPR ddPTM_HeLa_Curcumin_4h_R1 2 STSSSSDTMSTFKPMVAPR 19 1 G5EA48;Q7Z6B7-2;Q7Z6B7 G5EA48 SRGAP1 SLIT-ROBO Rho GTPase-activating protein 1 1 0 S(0.253)T(0.253)S(0.253)S(0.196)S(0.034)S(0.01)DTMSTFKPMVAPR;S(0.313)T(0.313)S(0.313)S(0.058)S(0.002)S(0.001)DTMSTFKPMVAPR ; 100.59 0.00041973 40630000 1949.85 1471.93 1872.13 1676.15 1450.65 1975.47 1197.69 1433.92 1707.31 1746.69 TRUE FALSE FALSE 1795.517315 1599.15707 1941.512785 1669.214535 1433.351946 1565.735254 1231.293958 1871.115607 1520.022364 1807.387347 0.993432491 0.884789347 1.07420957 0.923551079 0.793051887 0.866297563 0.681256267 1.035259879 0.841005314 1 10.81969001 -5.97178475 5.443265962 0.992297902 0.835353353 0.178641354 0.103808849 0.126545725 10.47090896 0.012125258 0.021922389 1.07E-06 5.97178475 -0.156944549 S(ph)TTELDDYSTNK ddPTM_HeLa_Curcumin_4h_R1 3 STTELDDYSTNK 12 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 S(0.989)T(0.01)TELDDYSTNK;S(0.895)T(0.104)T(0.001)ELDDYSTNK;S(0.658)T(0.042)T(0.3)ELDDYSTNK ;; 248.36 3.50E-27 171230000 7401.7 6613 7443.1 7288.1 7955.6 7874 6469.6 10190.2 7356.6 6544.5 TRUE FALSE FALSE 6815.847635 7184.598253 7718.947834 7257.943773 7860.734666 6240.843642 6651.119564 13297.14507 6549.599385 6771.920888 1.006486601 1.060939484 1.139846132 1.071770314 1.160783594 0.921576573 0.982161439 1.963570646 0.967170097 1 12.7253494 -4.259861312 24.96492943 1.024715118 1.963570962 0.937194909 0.072110415 22.72707218 359506.7271 0.010086175 0.085524139 5.50E-05 4.259861312 0.938855844 S(ph)TTPPPAEPVSLPQEPPKPR ddPTM_HeLa_Curcumin_4h_R1 4 STTPPPAEPVSLPQEPPKPR 20 1 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 0 S(0.355)T(0.355)T(0.29)PPPAEPVSLPQEPPKPR;S(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR;S(0.333)T(0.333)T(0.333)PPPAEPVSLPQEPPKPR;S(0.367)T(0.367)T(0.266)PPPAEPVSLPQEPPKPR ;;; 138.05 3.86E-05 3183942000 20314.6 19732.8 19731.3 18989.5 20114.5 22978.2 18529.6 19505.65 18418.6 17757.2 TRUE FALSE FALSE 18706.67797 21438.4153 20462.55934 18910.92648 19874.64772 18212.2623 19049.49071 25452.83289 16398.12566 18374.26138 1.018091426 1.16676338 1.113653437 1.029207438 1.081656961 0.991183369 1.036748651 1.385243867 0.892450876 1 14.16539864 -4.26163871 7.653797412 1.032642754 1.38874657 0.687678773 0.070438341 0.036469099 22.09284816 0.008406828 0.066972787 5.47E-05 4.26163871 0.356103815 EVAPVTNFSDS(ph)DDTMVAK ddPTM_HeLa_Curcumin_4h_R1 1 EVAPVTNFSDSDDTMVAK 18 0 G3V5D0;G3V290;G3V553;Q9NWQ4-1;Q9NWQ4-4;Q9NWQ4 G3V5D0 GPATCH2L G patch domain-containing protein 2-like 1 0 EVAPVTNFS(0.002)DS(0.499)DDT(0.499)MVAK 88.338 0.0040228 4389900 3725.5 2586.2 3142.4 3311.9 3404.1 3895.8 2971.1 852.2 3777.1 3027.8 TRUE FALSE FALSE 3430.622744 2809.739604 3258.860108 3298.196235 3363.508331 3087.767165 3054.46107 1112.031857 3362.76158 3133.015825 1.094990557 0.896816282 1.04016714 1.052722495 1.073568893 0.985557475 0.974926793 0.354939751 1.073330544 1 11.61333634 -4.246888659 3.468268954 1.033450432 0.259424863 0.931250267 0.054451774 0.060132561 1.20085498 0.007984123 0.123940702 5.66E-05 4.246888659 -0.774025569 down S(ph)TTTGHLIYK ddPTM_HeLa_Curcumin_4h_R1 1 STTTGHLIYK 10 0 A0A2U3TZH3;Q05639;A0A2R8Y488;A0A2R8Y660;A0A2R8YDN5;Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A6PW80;Q5JR01 A0A2U3TZH3;Q5VTE0 EEF1A2;EEF1A1P5;EEF1A1 Elongation factor 1-alpha 2;Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 1 0 S(0.986)T(0.013)T(0.001)TGHLIYK 110.08 0.0075736 6048700 2357 1927.4 1808 2053.8 3141.9 2541.2 1633.9 1177.4 2152.2 1965.3 TRUE FALSE FALSE 2170.440963 2093.995868 1875.00607 2045.30192 3104.434895 2014.126475 1679.742837 1536.38384 1916.109045 2033.594029 1.067293143 1.029702014 0.922015921 1.005757241 1.526575536 0.990427021 0.825997133 0.755501746 0.942227907 1 10.98981598 -4.774447166 4.143887235 1.056910817 0.780822219 0.315436969 0.161681714 0.179561199 6.930089095 0.022073405 0.080915604 1.68E-05 4.774447166 -0.276088598 S(ph)TVLGLPQHVQK ddPTM_HeLa_Curcumin_4h_R1 1 STVLGLPQHVQK 12 0 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 1 0 S(0.5)T(0.5)VLGLPQHVQK 89.9 0.015231 17320000 1509.4 1136.2 1380.2 1156.3 1703.3 1922.9 1716.2 1516.8 1424 1392.3 TRUE FALSE FALSE 1389.929397 1234.408065 1431.351426 1151.515537 1682.98926 1524.068864 1764.351953 1979.265338 1267.790763 1440.682321 0.964771606 0.856821831 0.993523281 0.799284839 1.168189014 1.057879896 1.224664124 1.373838846 0.879993281 1 10.49253653 -4.543034255 0.989865492 0.966007842 1.480261124 0.72032967 0.089772488 0.506900911 0.511077644 0.012690877 0.247839745 2.86E-05 4.543034255 0.514253282 S(ph)TY(ph)NYS(ph)LPITVK ddPTM_HeLa_Curcumin_4h_R1 1 STYNYSLPITVK 12 0 H0Y5D2;H7BY84;Q5T7U1;Q9Y5Q8-2;Q9Y5Q8;Q9Y5Q8-3 H0Y5D2 GTF3C5 General transcription factor 3C polypeptide 5 3 0 S(0.967)T(0.436)Y(0.531)NY(0.531)S(0.459)LPIT(0.076)VK 61.532 0.015143 13517000 858.5 805.36 879.53 647.97 831.64 1233.3 659.76 346.7 661.58 803.48 TRUE FALSE FALSE 790.5488191 874.9717298 912.1261555 645.2888718 821.7232362 977.4996778 678.2710899 452.407234 589.0063292 831.4008702 0.950863594 1.05240656 1.097095503 0.776146496 0.988359846 1.17572607 0.815817152 0.544150542 0.70845046 1 9.699400448 -4.416371869 3.545183836 0.987855416 0.548636899 0.477199791 0.133920721 0.111791702 2.320562134 0.013323216 0.09904114 3.83E-05 4.416371869 -0.439218517 S(ph)VASSQPAKPTK ddPTM_HeLa_Curcumin_4h_R1 2 SVASSQPAKPTK 12 1 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 0 S(0.987)VAS(0.013)SQPAKPTK;S(0.922)VAS(0.078)SQPAKPTK ; 164.22 0.0011279 44291000 4935.9 4314.9 3991.1 4602.1 5162.8 4939.1 4196.9 4465.7 5080.5 3743.7 TRUE FALSE FALSE 4545.218307 4687.860729 4139.013677 4583.05773 5101.236982 3914.674985 4314.653719 5827.271372 4523.181861 3873.793296 1.173324945 1.21014736 1.06846529 1.183092999 1.316858333 1.0105534 1.113805872 1.504280411 1.167636349 1 11.91953126 -13.52287875 0.096299934 0.370127129 1.343436439 0.12314919 0.133308077 127.6150746 0.922360713 16.46350422 1.19953531 3.00E-14 13.52287875 0.973309309 ESCS(ph)SPSTVGSSLTTR ddPTM_HeLa_Curcumin_4h_R1 1 ESCSSPSTVGSSLTTR 16 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;H0YEP9 E9PMC9 C11orf30;EMSY Protein EMSY 1 0 ESCS(0.912)S(0.08)PS(0.004)T(0.004)VGSSLTTR 200.97 3.36E-10 30308000 4676.5 3371.5 3703.5 3956.4 3890.3 4552.7 3543.9 1057.9 3763.4 3315.8 TRUE FALSE FALSE 4306.35009 3662.917437 3840.754968 3940.029465 3843.910713 3608.4187 3643.332296 1380.44884 3350.564436 3431.023803 1.255121019 1.0675873 1.119419505 1.148353871 1.120339273 1.051703196 1.06187905 0.402343125 0.976549458 1 11.74442342 -4.246851583 3.579925792 1.116302111 0.307910884 0.874805454 0.077561835 0.088747837 1.964875579 0.012991926 0.195079168 5.66E-05 4.246851583 -0.808391227 down S(ph)VDEIAK ddPTM_HeLa_Curcumin_4h_R1 2 SVDEIAK 7 0 A6ND36;A6ND36-2 A6ND36 FAM83G Protein FAM83G 1 0 S(1)VDEIAK;S(1)VDEIAK ; 103.55 0.017816 14335800 5599.7 5057.1 4724.9 5267.7 5850.1 12648.5 10873.7 7045.4 6591 5337.9 TRUE FALSE FALSE 5156.477836 5494.21319 4900.00895 5245.903653 5780.341378 10025.05852 11178.78676 9193.510027 5867.98379 5523.391628 0.933570926 0.994717297 0.887137701 0.949761307 1.046520285 1.815018597 2.023898994 1.664468255 1.062387784 1 12.43133871 -5.272358793 4.313336962 0.963621176 1.865172002 0.947430738 0.092131142 0.025329721 1.19104513 0.011297515 0.027943054 5.34E-06 5.272358793 0.901550826 S(ph)VDEVNYWDK ddPTM_HeLa_Curcumin_4h_R1 2 SVDEVNYWDK 10 0 F5GXU9;F5H5P2;P12694;P12694-2 F5GXU9 BCKDHA "2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial" 1 0 S(1)VDEVNYWDK;S(1)VDEVNYWDK ; 173.06 0.0004377 11830800 3062.1 2926 2808.9 2948.1 3844.6 3437 3548.6 3448.6 2586.18 2267.9 TRUE FALSE FALSE 2819.731554 3178.910402 2913.000305 2935.901543 3798.755656 2724.127457 3648.164165 4500.062265 2302.482524 2346.709356 1.201568292 1.354624676 1.241312776 1.251071649 1.618758474 1.160828651 1.554587131 1.917605285 0.981153682 1 11.19642346 -1 0.196251105 1.000470195 4.531603646 0.699047629 0.152176042 21.64112745 0.245966564 0.147516988 23.53985776 0.1 1 3.531133452 S(ph)VDFDSLTVR ddPTM_HeLa_Curcumin_4h_R1 3 SVDFDSLTVR 10 0 Q9Y5K6 Q9Y5K6 CD2AP CD2-associated protein 1 0 S(0.998)VDFDS(0.002)LTVR;S(1)VDFDSLTVR;S(1)VDFDSLTVR ;; 174.57 0.00041194 143145000 2652.6 2779.35 2296.89 2045.3 2255.53 3272.35 2518.27 2277.69 3474.13 2566.13 TRUE FALSE FALSE 2442.643911 3019.584629 2382.014764 2036.837091 2228.634278 2593.627723 2588.925879 2972.147196 3093.026631 2655.302826 0.919911615 1.137190304 0.897078382 0.767082786 0.839314543 0.976772855 0.975002118 1.119325135 1.16484892 1 11.37466069 -5.857097683 0.003850878 1.900609668 8.82E-08 0 0.124687757 140556.8008 167.2346904 40715.66696 41824.26281 1.39E-06 5.857097683 -1.90060958 SQS(ph)S(ph)DTEQQS(ph)PTSGGGK ddPTM_HeLa_Curcumin_4h_R1 1 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 3 0 S(0.108)QS(0.912)S(0.975)DT(0.368)EQQS(0.52)PT(0.102)S(0.015)GGGK 97.095 0.0069778 13478000 1692.3 1988.5 1659.4 1879.4 1737.9 2692.4 3385.5 6170.7 2194.3 1737.6 TRUE FALSE FALSE 1558.352669 2160.377079 1720.898824 1871.623541 1717.176678 2133.96589 3480.488018 8052.118024 1953.59078 1797.981471 0.866723431 1.201556921 0.957128231 1.040958192 0.95505805 1.186867565 1.935775243 4.478421027 1.08654667 1 10.81216244 -4.141138465 1.621053046 0.966134925 6.572323243 0.990647096 0.100801386 0.086444086 0.169680577 0.014659882 0.829414617 7.23E-05 4.141138465 5.606188318 up S(ph)VEAAAELSAK ddPTM_HeLa_Curcumin_4h_R1 2 SVEAAAELSAK 11 0 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 1 0 S(1)VEAAAELSAK;S(1)VEAAAELSAK ; 170.66 0.00023712 10098800 2649.3 2451.7 2639.5 2968.9 3494.3 2780.9 2465.5 2225.17 2423.8 2637.7 TRUE FALSE FALSE 2439.605109 2663.614023 2737.322192 2956.615478 3452.632755 2204.109993 2534.675294 2903.61409 2157.915204 2729.359879 0.893837829 0.975911621 1.002917282 1.083263333 1.264997255 0.807555651 0.92867024 1.063844351 0.790630514 1 11.41434692 -6.784453378 3.290090364 0.949515101 1.025620888 0.143236738 0.122622703 0.495506043 11.17266801 0.019118139 0.026418105 1.64E-07 6.784453378 0.076105787 S(ph)VEDDEEGHLICQSGDVLSAR ddPTM_HeLa_Curcumin_4h_R1 2 SVEDDEEGHLICQSGDVLSAR 21 0 F8WBF5;P49759;P49759-3 F8WBF5 CLK1 Dual specificity protein kinase CLK1 1 0 S(1)VEDDEEGHLICQSGDVLSAR;S(1)VEDDEEGHLICQSGDVLSAR ; 203.29 1.22E-17 55133000 3311.7 2289.9 2610.7 2956 2965.9 4455 3779 1687.73 3397.4 2717.9 TRUE FALSE FALSE 3049.575451 2487.828752 2707.454839 2943.768855 2930.53358 3530.982782 3885.028569 2202.311108 3024.71372 2812.346823 1.084352551 0.884609513 0.962703041 1.046730379 1.042024247 1.255528925 1.381418728 0.783086599 1.075512343 1 11.45755881 -5.408077766 6.955773283 1.022703305 1.163700133 0.120254132 0.152016361 0.347746288 18.93907831 0.020216501 0.045419852 3.91E-06 5.408077766 0.140996828 S(ph)VEDDKEGHLVCR ddPTM_HeLa_Curcumin_4h_R1 2 SVEDDKEGHLVCR 13 1 H3BUL5;H3BVF8;H3BQG1;P49761-3;P49761-1;P49761 H3BUL5 CLK3 Dual specificity protein kinase CLK3 1 0 S(1)VEDDKEGHLVCR;S(1)VEDDKEGHLVCR ; 77.776 0.0092743 26418000 5977.9 5301.2 5472.1 5438.2 6205.9 5675.7 4067.3 2320.58 4944.2 5638.6 TRUE FALSE FALSE 5504.742907 5759.412106 5674.90084 5415.698169 6131.898696 4498.495842 4181.417491 3028.114159 4401.83363 5834.54093 0.943474898 0.987123439 0.972638792 0.928213245 1.050965066 0.771011104 0.716666065 0.518997843 0.754443868 1 12.51040343 -4.694152781 1.3585464 0.975370207 0.497853664 0.715736116 0.084676673 0.128384475 0.341835349 0.006726649 0.067592667 2.02E-05 4.694152781 -0.477516543 S(ph)VEEPTQPGGTGLSDSR ddPTM_HeLa_Curcumin_4h_R1 2 SVEEPTQPGGTGLSDSR 17 0 Q9H0B6;Q9H0B6-2 Q9H0B6 KLC2 Kinesin light chain 2 1 0 S(1)VEEPTQPGGTGLSDSR;S(0.984)VEEPT(0.016)QPGGTGLSDSR ; 243.61 1.46E-30 59319000 3269.4 2712 3374 3349.2 3794.3 4870.4 4225.8 2010.06 3036.2 2742.6 TRUE FALSE FALSE 3010.62354 2946.413196 3499.043408 3335.341898 3749.055451 3860.224139 4344.364575 2622.918041 2703.136456 2837.905146 1.060861229 1.038235263 1.232967005 1.175283079 1.321064397 1.360237196 1.530835018 0.924244436 0.952511207 1 11.47061065 -6.56324139 1.17159243 1.024228127 1.301330645 0.38883342 0.147917903 0.311525807 0.855576685 0.024303186 0.041004273 2.73E-07 6.56324139 0.277102518 S(ph)VELDLNQAHMEETPK ddPTM_HeLa_Curcumin_4h_R1 3 SVELDLNQAHMEETPK 16 0 Q14680-3;Q14680-4;Q14680-5;Q14680-2;Q14680-8;Q14680-6;Q14680;Q14680-7 Q14680-3 MELK Maternal embryonic leucine zipper kinase 1 0 S(1)VELDLNQAHMEETPK;S(1)VELDLNQAHMEETPK;S(1)VELDLNQAHMEETPK ;; 250.27 3.71E-82 12143000 7566.9 6682.6 6513.5 7548.7 7565.9 7031.4 5926.93 3399.92 7934.3 7917.7 TRUE FALSE FALSE 6967.97188 7260.214167 6754.89604 7517.46548 7475.681584 5573.00838 6093.223704 4436.539957 7063.927141 8192.839486 0.850495349 0.886165801 0.82448778 0.917565332 0.912465281 0.680229167 0.743725507 0.541514327 0.862207438 1 13.00014783 -3.360963081 0.370645165 0.940824887 3.03E-36 0.730004192 0.065818705 4.206272729 0.242087426 0.020261707 2.02908546 0.000435549 3.360963081 -0.940824887 S(ph)VENLPECGITHEQR ddPTM_HeLa_Curcumin_4h_R1 4 SVENLPECGITHEQR 15 0 Q9UBF8-2;A0A0B4J1S8;Q9UBF8;F8W860;Q9UBF8-3 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 0 S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR;S(1)VENLPECGITHEQR ;;; 196.76 4.87E-07 772397000 19508.4 16092 15611.1 17437.3 16316.2 15599.8 11534.4 10435.7 19180.6 17336.3 TRUE FALSE FALSE 17964.28955 17482.92078 16189.6611 17365.14907 16121.63997 12364.22563 11858.02422 13617.49689 17076.53617 17938.73513 1.001424539 0.974590496 0.90249736 0.968025278 0.898705502 0.689247349 0.661029004 0.759111319 0.951936468 1 14.13079055 -5.418831722 2.461661494 0.988649332 0.695079157 0.895180591 0.039759734 0.059212778 0.696243546 0.005990662 0.015327059 3.81E-06 5.418831722 -0.293570175 S(ph)VENQESVEIINDLK ddPTM_HeLa_Curcumin_4h_R1 1 SVENQESVEIINDLK 15 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 0 S(0.953)VENQES(0.047)VEIINDLK 79.326 0.016376 3990000 638.2 668.24 601.93 890.13 571.91 1105.1 863.22 326.59 858.25 631.31 TRUE FALSE FALSE 587.6857966 725.999688 624.2380553 886.4468779 565.0903468 875.889803 887.43963 426.1657876 764.1021222 653.2479755 0.899636614 1.111369212 0.955591259 1.356983735 0.865047222 1.340822836 1.358503452 0.652379806 1.169696885 1 9.351486938 -6.882821224 1.76199971 0.954515577 1.121692755 0 0.229552171 0.574295076 3.598624809 0.035610455 0.049052112 1.31E-07 6.882821224 0.167177178 S(ph)VEPQDAGPLER ddPTM_HeLa_Curcumin_4h_R1 4 SVEPQDAGPLER 12 0 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 0 S(1)VEPQDAGPLER;S(1)VEPQDAGPLER;S(1)VEPQDAGPLER;S(1)VEPQDAGPLER ;;; 168.93 0.000128 80422000 5396.17 4253.66 4671.44 4271.54 4501.71 5386.4 4060.86 2717.33 5240.49 5220.89 TRUE FALSE FALSE 4969.05745 4621.327416 4844.567676 4253.865499 4448.030048 4269.199923 4174.796802 3545.831408 4665.621358 5402.315539 0.91980141 0.85543456 0.896757629 0.787415224 0.82335621 0.790253715 0.772779149 0.656353999 0.863633626 1 12.39936219 -1.927468686 0.14171908 1.056789296 2.27E-20 0.676345002 0.050767013 9.540424444 0.113752124 0.075009214 1.970331008 0.011817655 1.927468686 -1.056789296 S(ph)VEYEGDLK ddPTM_HeLa_Curcumin_4h_R1 2 SVEYEGDLK 9 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0;H7C3N7 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 S(1)VEYEGDLK;S(1)VEYEGDLK ; 135.8 3.04E-05 13138000 2630.46 2287.92 2380.06 2387.99 3090.23 2899.43 1943.18 1969.15 2455.88 2349.46 TRUE FALSE FALSE 2422.256315 2485.67761 2468.267117 2378.10913 3053.381026 2298.055535 1997.700401 2569.53477 2186.476108 2431.10356 0.996360811 1.022448262 1.015286703 0.978201492 1.255965018 0.94527258 0.821725752 1.056941717 0.899375964 1 11.24739564 -5.022511038 24.98195682 1.017914312 0.925375019 0.119417857 0.100579565 945.7987817 1049616.048 0.012416364 0.031935788 9.49E-06 5.022511038 -0.092539293 S(ph)VFGTPTLETANK ddPTM_HeLa_Curcumin_4h_R1 1 SVFGTPTLETANK 13 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 S(0.432)VFGT(0.423)PT(0.045)LET(0.1)ANK 146.67 0.0006996 16235000 4114.4 2972.6 3082.4 2786 3770.4 4768.8 4377.6 1507 3109 2130.5 TRUE FALSE FALSE 3788.740899 3229.538298 3196.636456 2774.47227 3725.440443 3779.697125 4500.423674 1966.477363 2767.950478 2204.534716 1.71861249 1.464952343 1.450027723 1.258529634 1.689898741 1.71451014 2.041439239 0.892014695 1.255571281 1 11.10625848 -9.401853022 1.021512069 0.985826807 1.557878507 0.199726108 0.301777853 0.50303347 0.901114616 0.216720113 0.049946285 3.96E-10 9.401853022 0.572051699 S(ph)VGDGETVEFDVVEGEK ddPTM_HeLa_Curcumin_4h_R1 2 SVGDGETVEFDVVEGEK 17 0 H0Y449;P67809;A0A0D9SEI8;Q9Y2T7;P16989-2;P16989;P16989-3 H0Y449;P16989-2 YBX1;YBX3;YBX2 Nuclease-sensitive element-binding protein 1;Y-box-binding protein 2;Y-box-binding protein 3 1 0 S(1)VGDGETVEFDVVEGEK;S(1)VGDGETVEFDVVEGEK ; 231.21 3.06E-22 31112000 5556.5 4888.5 5958.9 5523 6501.1 6481.7 5172 8442.9 6065.9 4715.5 TRUE FALSE FALSE 5116.697162 5311.040157 6179.742076 5500.147289 6423.578629 5137.322356 5317.1124 11017.10134 5400.485946 4879.363274 1.04864034 1.088469921 1.266505839 1.127226439 1.316478866 1.052867366 1.089714395 2.257897337 1.106801368 1 12.25247718 -4.261457872 7.348989064 1.075366409 2.272066031 0.915509132 0.102674064 0.021988134 10.5877344 0.016118314 0.129905858 5.48E-05 4.261457872 1.196699622 S(ph)VGGSGGGSFGDNLVTR ddPTM_HeLa_Curcumin_4h_R1 1 SVGGSGGGSFGDNLVTR 17 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 0 S(1)VGGSGGGSFGDNLVTR 234.36 1.51E-22 108150000 1973.5 1434.3 1489.5 1835.9 1846.7 2196.8 3068.6 1799.1 1956.2 1804.7 TRUE FALSE FALSE 1817.295393 1558.274501 1544.70218 1828.303532 1824.679309 1741.158917 3154.696657 2347.637308 1741.609754 1867.413191 0.973161913 0.834456192 0.827188213 0.979056773 0.977116001 0.93239082 1.689340459 1.257160076 0.932632244 1 10.86682546 -4.774803054 24.99580449 0.96045274 1.473250249 0.7792658 0.114427016 62.42601598 116764.1284 0.014827594 0.044850561 1.68E-05 4.774803054 0.512797509 GSSGENNNPGS(ph)PTVSNFR ddPTM_HeLa_Curcumin_4h_R1 1 GSSGENNNPGSPTVSNFR 18 0 D6R8Z7;D6RDZ7;D6RD37;D6RAX8;D6RBL1;D6RDZ9;D6RCK9;Q99576-3 D6R8Z7 TSC22D3 1 0 GSSGENNNPGS(1)PTVSNFR 241.98 6.14E-32 20797000 2506.8 1792 1912.1 2034.2 2135 3069.5 2891.8 3524.4 2284 2028 TRUE FALSE FALSE 2308.384135 1946.892495 1982.964108 2025.783019 2109.541519 2432.8511 2972.936125 4598.973336 2033.450914 2098.472849 1.100030499 0.92776635 0.944955809 0.965360605 1.005274631 1.159343615 1.416714124 2.191581053 0.969014641 1 11.03512408 -4.140884568 1.399996604 1.022525767 2.934623429 0.97647715 0.056500194 0.200495868 0.280229086 0.009902197 0.580544805 7.23E-05 4.140884568 1.912097662 up S(ph)VILDGR ddPTM_HeLa_Curcumin_4h_R1 2 SVILDGR 7 0 Q2M1Z3 Q2M1Z3 ARHGAP31 Rho GTPase-activating protein 31 1 0 S(1)VILDGR;S(1)VILDGR ; 119.75 0.012173 10714900 8130.2 6683.8 7147.4 7922.2 8376.4 12695.2 8744.7 2177.6 8786.7 6808.7 TRUE FALSE FALSE 7486.686091 7261.51789 7412.288931 7889.420036 8276.516901 10062.07242 8990.052747 2841.540216 7822.820993 7045.301818 1.062649448 1.030689398 1.052089623 1.119812925 1.174756897 1.428196077 1.276035148 0.403324128 1.110359953 1 12.7824458 -6.374664717 3.602049939 1.030837949 1.115861759 0 0.253524013 0.934679583 22.216492 0.037797276 0.059206819 4.22E-07 6.374664717 0.08502381 TT(ph)DIVIRIGNT(ph)EDGAPHK ddPTM_HeLa_Curcumin_4h_R1 1 TTDIVIRIGNTEDGAPHK 18 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 2 0 T(0.422)T(0.578)DIVIRIGNT(1)EDGAPHK 87.85 0.0032331 4419400 2304.5 2051 2008.4 2575.2 2173.1 3450.8 3341.8 4133.5 2748.8 2460.8 TRUE FALSE FALSE 2122.096393 2228.279301 2082.833071 2564.544505 2147.187202 2735.065181 3435.561914 5393.785122 2447.263517 2546.312617 0.833399787 0.875100444 0.817980109 1.007160114 0.843253569 1.074127805 1.349230213 2.118272943 0.961100967 1 11.31419384 -4.138698154 1.317390247 0.908983536 2.912236974 0.967269439 0.067770754 0.240000716 0.29100783 0.011581994 0.692290001 7.27E-05 4.138698154 2.003253438 up S(ph)VLQIEQLQS(ph)MRS(ph)SQQT(ph)AFS(ph)TIK ddPTM_HeLa_Curcumin_4h_R1 1 SVLQIEQLQSMRSSQQTAFSTIK 23 1 Q495C1-3;Q495C1-5;Q495C1 Q495C1-3 RNF212 Probable E3 SUMO-protein ligase RNF212 5 0 S(0.999)VLQIEQLQS(0.991)MRS(0.505)S(0.505)QQT(0.736)AFS(0.646)T(0.618)IK 51.236 0.0066859 0 715.95 633.36 724.03 815.04 721.53 871.6 782.23 532.64 783.3 775.91 TRUE FALSE FALSE 659.281802 688.1048162 750.8631887 811.6675804 712.926226 690.820335 804.1772685 695.039484 697.3739497 802.8728147 0.821153475 0.857053326 0.935220592 1.010954121 0.887969069 0.860435579 1.001624733 0.865690644 0.868598285 1 9.649027654 -6.951979565 0.006475508 1.822328995 7.72E-07 0 0.067900436 9585.052144 43.85472199 6130.988825 6208.00754 1.12E-07 6.951979565 -1.822328223 S(ph)VNFSLT(ph)PNEIK ddPTM_HeLa_Curcumin_4h_R1 3 SVNFSLTPNEIK 12 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 S(1)VNFS(0.003)LT(0.997)PNEIK;S(1)VNFSLT(1)PNEIK;S(1)VNFSLT(1)PNEIK ;; 160.93 0.0008908 25550200 15065.1 14848.4 14502.6 15390.9 17268.6 28323.4 30850 11767.3 14612.8 12501 TRUE FALSE FALSE 13872.68144 16131.82953 15040.07911 15327.21653 17062.68322 22448.80757 31715.56797 15355.0956 13009.8124 12935.40882 1.072457905 1.247106277 1.162706129 1.184903914 1.319067952 1.735454046 2.451841176 1.187059166 1.005751931 1 13.65903803 -5.393094902 2.272104982 1.072374943 1.872706746 0.510170391 0.295221586 0.151794512 1.517733539 0.039500055 0.105654623 4.04E-06 5.393094902 0.800331803 S(ph)VPEDDGHALLAER ddPTM_HeLa_Curcumin_4h_R1 2 SVPEDDGHALLAER 14 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 S(1)VPEDDGHALLAER;S(1)VPEDDGHALLAER ; 171.78 9.40E-05 12865900 1464.27 1325.42 1289.44 1273.13 1439.92 1669.89 1218.3 1025.88 1641.56 1263.08 TRUE FALSE FALSE 1348.371484 1439.983399 1337.227781 1267.862125 1422.749894 1323.53599 1252.482219 1338.666089 1461.484975 1306.971936 1.031675928 1.101770711 1.023149575 0.970076013 1.088584885 1.012673611 0.958308426 1.024250064 1.118222155 1 10.35201245 -4.988305491 24.78171753 1.024391946 0.989832175 0.061110977 0.049689476 344.9987352 731072.3304 0.005566983 0.016683319 1.03E-05 4.988305491 -0.03455977 S(ph)VPSETVVEDSR ddPTM_HeLa_Curcumin_4h_R1 1 SVPSETVVEDSR 12 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 S(1)VPSETVVEDSR 103.97 0.007371 15344000 895.57 749.53 889.58 637.26 624.97 1068.3 807.76 779.87 815.3 789.64 TRUE FALSE FALSE 824.6846895 814.3160334 922.5486174 634.623187 617.5176409 846.7225378 830.4235716 1017.648773 725.8636298 817.0799312 1.009307239 0.996617347 1.129080011 0.776696579 0.755761606 1.036278711 1.016330887 1.245470283 0.888363062 1 9.674333407 -4.193061562 2.333124985 0.980843268 1.339870785 0.358583733 0.1128206 0.703484467 3.837825706 0.015794348 0.546368212 6.41E-05 4.193061562 0.359027517 AENGLLMT(ph)PCYTANFVAPEVLKR ddPTM_HeLa_Curcumin_4h_R1 1 AENGLLMTPCYTANFVAPEVLKR 23 1 B4DG22;B1AXG1;B7ZB17;P51812;A0A2R8Y603;E9PGT3;Q15418-3;Q15418-4;Q15418;Q15418-2 B4DG22;E9PGT3 RPS6KA3;RPS6KA1 Ribosomal protein S6 kinase alpha-3;Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-1 1 0 AENGLLMT(0.791)PCY(0.186)T(0.023)ANFVAPEVLKR 83.871 0.00021813 7911700 201.8 192.44 295.62 132.86 144.92 626.66 763.5 2343.4 279.91 386.57 TRUE FALSE FALSE 185.8273171 209.0736561 306.5759373 132.3102605 143.1919237 496.6836521 784.9217551 3057.891872 249.2045733 400.0032787 0.464564485 0.522679856 0.766433561 0.33077294 0.357976875 1.241698952 1.962288303 7.644667019 0.623006327 1 8.643868015 -4.138285646 1.918857658 0.68438409 11.47100415 0.984397575 0.26288204 0.112657977 0.327791833 0.04363971 2.390409053 7.27E-05 4.138285646 10.78662006 up S(ph)VQEGENPDDGVR ddPTM_HeLa_Curcumin_4h_R1 2 SVQEGENPDDGVR 13 0 H7C5M1;Q5TCT4;A2A2V2;P42696-2;P42696 H7C5M1 RBM34 RNA-binding protein 34 1 0 S(1)VQEGENPDDGVR;S(1)VQEGENPDDGVR ; 199.61 8.71E-07 74916000 713.13 825.68 979.78 1069.78 984.5 872.73 459.48 818.04 902.22 880.69 TRUE FALSE FALSE 656.685008 897.0481 1016.091509 1065.353534 972.7604805 691.7159603 472.3717722 1067.45663 803.2487232 911.2939119 0.720607259 0.984367489 1.11499868 1.16905591 1.067449774 0.759048153 0.518352823 1.171363724 0.881437605 1 9.831772619 -3.966929201 22.07403626 0.896699755 2.646376917 0.137516905 0.190441671 403.4853617 463503.6704 0.028504846 82310.69063 0.000107912 3.966929201 1.749677161 S(ph)VS(ph)PCSNVESR ddPTM_HeLa_Curcumin_4h_R1 1 SVSPCSNVESR 11 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(1)VS(0.999)PCS(0.001)NVESR 111.72 0.014514 499130000 6941.3 5907.5 5834.8 6356.1 6040.7 7214.5 5785.3 3928.5 6494.9 5779.7 TRUE FALSE FALSE 6391.888781 6418.117977 6051.042821 6329.800142 5968.668598 5718.131376 5947.619948 5126.281565 5782.425719 5980.544145 1.06878047 1.073166224 1.011788004 1.058398699 0.998014303 0.956122259 0.994494782 0.857159723 0.966872843 1 12.54606104 -2.917492614 0.662759183 1.03581498 1.46E-13 0.628259705 0.03712226 6.472427121 0.504543916 0.005992924 7.621685274 0.001209226 2.917492614 -1.03581498 S(ph)VSEINS(ph)DDELSGK ddPTM_HeLa_Curcumin_4h_R1 2 SVSEINSDDELSGK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 2 0 S(1)VSEINS(1)DDELSGK;S(1)VSEINS(1)DDELSGK ; 268.08 8.40E-50 35775000 11432.2 9699.6 9953 10464.4 10844.9 11725.6 9590.9 5248.9 10744.4 9821.1 TRUE FALSE FALSE 10527.32931 10537.9902 10321.86694 10421.10109 10715.58165 9293.578385 9859.994841 6849.265447 9565.766201 10162.38249 1.035911541 1.036960596 1.015693607 1.025458458 1.054435971 0.914507832 0.970244413 0.673982253 0.941291691 1 13.31095105 -3.746037042 1.208023642 1.019522034 8.01E-12 0.843648301 0.042116965 0.91808773 0.47011643 0.004738474 1.589641403 0.000179458 3.746037042 -1.019522034 S(ph)VSEINSDDELSGK ddPTM_HeLa_Curcumin_4h_R1 3 SVSEINSDDELSGK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 0 S(0.861)VS(0.033)EINS(0.106)DDELSGK;S(1)VSEINSDDELSGK;S(0.999)VS(0.001)EINSDDELSGK ;; 298.7 1.36E-91 356731000 12221.9 12780.8 11080.3 12701.4 12419.8 12931.4 9256.7 7088.2 12812.5 10338.2 TRUE FALSE FALSE 11254.52372 13885.5154 11490.94567 12648.84497 12271.702 10249.28187 9516.418089 9249.35955 11407.00081 10697.45168 1.05207521 1.298020857 1.074175982 1.182416649 1.147161246 0.958104994 0.889596735 0.864632048 1.066328799 1 13.38497954 -5.011365361 3.932359305 1.069124793 0.881785096 0.51835851 0.087860382 0.17331591 6.050669046 0.014456274 0.043604458 9.74E-06 5.011365361 -0.187339697 S(ph)VSGS(ph)PEPAAK ddPTM_HeLa_Curcumin_4h_R1 3 SVSGSPEPAAK 11 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 0 S(0.997)VS(0.004)GS(0.999)PEPAAK;S(0.97)VS(0.508)GS(0.522)PEPAAK;S(0.963)VS(0.091)GS(0.946)PEPAAK ;; 145.83 0.002258 467610000 36287 29873.3 30882.1 32357 33425 37815 30343.1 26954.1 35662 28181.3 TRUE FALSE FALSE 33414.84566 32455.41494 32026.61779 32223.11531 33026.42871 29971.74274 31194.44572 35172.28101 31749.96782 29160.59808 1.145890272 1.112988659 1.098283983 1.105022442 1.132570348 1.027816462 1.069746431 1.206157738 1.088796867 1 14.83173269 -9.405498748 1.086903275 0.998879366 1.111147358 0.137599693 0.051595245 0.368344784 0.765948134 0.031937511 0.007793299 3.93E-10 9.405498748 0.112267992 S(ph)VSGSPEPAAK ddPTM_HeLa_Curcumin_4h_R1 2 SVSGSPEPAAK 11 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 S(0.958)VS(0.039)GS(0.003)PEPAAK;S(0.995)VS(0.001)GS(0.004)PEPAAK ; 185.25 8.85E-05 29672600 7355.6 6872.9 6779.8 7540.9 7950.4 8573.4 4355 4637.2 8334.3 7354 TRUE FALSE FALSE 6773.396498 7466.962851 7031.065352 7509.697754 7855.596673 6795.180198 4477.189579 6051.060933 7420.048141 7609.550953 0.890117767 0.981261956 0.92397901 0.986877912 1.032333803 0.892980445 0.588364492 0.795192906 0.975096716 1 12.89359561 -4.905820459 5.801774059 0.955767029 0.694826272 0.762936236 0.060751914 0.072539148 3.636806023 0.008710386 0.026914862 1.24E-05 4.905820459 -0.260940757 S(ph)VSPCSNVESR ddPTM_HeLa_Curcumin_4h_R1 1 SVSPCSNVESR 11 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.59)VS(0.399)PCS(0.007)NVES(0.003)R 101.72 0.010041 62141000 2801.3 3920.5 2807.7 2460.8 2413.8 2647.3 2282.1 3532.2 2447.8 2900.4 TRUE FALSE FALSE 2579.574149 4259.370551 2911.755832 2450.617862 2385.017012 2098.220139 2346.129584 4609.15152 2179.282464 3001.188684 0.859517485 1.419227846 0.970200857 0.816549081 0.794690792 0.699129698 0.78173345 1.535775323 0.726139771 1 11.55131831 -6.484142893 23.68833739 0.979010142 0.897296908 0.009057659 0.273821509 1208.882802 739273.5371 0.039995885 0.061084164 3.28E-07 6.484142893 -0.081713234 SIDAVIATASAPPS(ph)SSPGR ddPTM_HeLa_Curcumin_4h_R1 2 SIDAVIATASAPPSSSPGR 19 0 Q9NR48-2;Q9NR48 Q9NR48-2 ASH1L Histone-lysine N-methyltransferase ASH1L 1 0 SIDAVIAT(0.019)AS(0.046)APPS(0.52)S(0.208)S(0.208)PGR;SIDAVIATAS(0.001)APPS(0.333)S(0.333)S(0.333)PGR ; 184.92 1.37E-07 61743000 4758.4 4028.2 4218.3 4400.1 4172.4 4904.3 2713.5 1335.36 5414.4 4564.1 TRUE FALSE FALSE 4381.767619 4376.379659 4374.633909 4381.893552 4122.646855 3887.092897 2789.633507 1742.505117 4820.453866 4722.702135 0.927809439 0.926668575 0.926298925 0.927836105 0.872942383 0.823065437 0.590685889 0.368963586 1.020698263 1 12.20539683 -4.245075775 0.845337718 0.95977214 5.89E-16 0.973730722 0.031345177 0.259645918 0.132138266 0.005255596 0.233263366 5.69E-05 4.245075775 -0.95977214 down S(ph)AEALGPGALVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SAEALGPGALVSPR 14 0 Q9P227-2;Q9P227 Q9P227-2 ARHGAP23 Rho GTPase-activating protein 23 2 0 S(1)AEALGPGALVS(1)PR 170.79 0.00048093 2141300 1712.5 1513 1300.6 1710.1 1426.4 1582.5 1180.7 366.96 2107.1 1671.8 TRUE FALSE FALSE 1576.953818 1643.776978 1348.80138 1703.024059 1409.391112 1254.271662 1213.827264 478.8444147 1875.956402 1729.894926 0.911589366 0.950217816 0.779701333 0.984466764 0.814726427 0.725056559 0.701676874 0.276805491 1.084433727 1 10.7564687 -4.244679536 0.765990017 0.947541306 1.53E-29 0.839173227 0.087344418 0.671448735 0.273768832 0.012291354 0.546932873 5.69E-05 4.244679536 -0.947541306 down S(ph)GVSITIDDPVR ddPTM_HeLa_Curcumin_4h_R1 3 SGVSITIDDPVR 12 0 S4R3H4;E7EQT4;Q9UKV3;G3V3B0;Q9UKV3-3;Q9UKV3-2;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 S(0.999)GVS(0.001)ITIDDPVR;S(0.998)GVS(0.002)ITIDDPVR;S(0.962)GVS(0.005)IT(0.033)IDDPVR ;; 162.93 0.00014604 15658700 4375.4 3730.21 3898.47 4708 4267.6 6151 6653.7 12270.6 4909.4 4175.1 TRUE FALSE FALSE 4029.082473 4052.632731 4042.950728 4688.519543 4216.711657 4875.213264 6840.384914 16011.84945 4370.851103 4320.184414 0.932618168 0.938069384 0.935828275 1.085259122 0.976048995 1.128473416 1.583354843 3.706288417 1.011727899 1 12.07687718 -4.137752207 1.790131879 0.974064565 5.274065106 0.994773378 0.058794491 0.061718699 0.151975121 0.008813249 0.493937131 7.28E-05 4.137752207 4.300000541 up QS(ph)SFEPEFVISPR ddPTM_HeLa_Curcumin_4h_R1 1 QSSFEPEFVISPR 13 0 A0A0A0MSU3;Q9H9A7 A0A0A0MSU3 RMI1 RecQ-mediated genome instability protein 1 1 0 QS(0.682)S(0.318)FEPEFVISPR 123.1 0.0022212 3920800 549.46 508.73 645.86 805.55 554.31 830.55 883.42 1673.7 697.64 542.07 TRUE FALSE FALSE 505.9696612 552.7023543 669.7961398 802.2168475 547.7002153 658.2845678 908.2063876 2184.003425 621.1106374 560.9068922 0.902056417 0.985372728 1.1941307 1.430213925 0.976454779 1.173607558 1.619174947 3.893700462 1.107332868 1 9.1316175 -4.135272329 1.828354711 1.013266327 5.545365422 0.96523974 0.158179386 0.163516852 0.421011472 0.024871953 1.406046906 7.32E-05 4.135272329 4.532099095 up S(ph)VSSFPVPQDNVDTHPGSGK ddPTM_HeLa_Curcumin_4h_R1 1 SVSSFPVPQDNVDTHPGSGK 20 0 C9JAY7;E7EVC7;Q676U5-4;Q676U5-5;Q676U5-3;Q676U5-2;Q676U5 C9JAY7 ATG16L1 Autophagy-related protein 16-1 1 0 S(0.834)VS(0.083)S(0.083)FPVPQDNVDTHPGSGK 82.294 0.0011228 18339000 3197.1 2821.3 2867.4 2684.6 3650.6 6433.9 4683.1 4056.8 3577.6 3050.7 TRUE FALSE FALSE 2944.046161 3065.160601 2973.668366 2673.491837 3607.068979 5099.436615 4814.495182 5293.699645 3185.146231 3156.711598 0.932630704 0.970997985 0.942014585 0.846923057 1.142666622 1.615426832 1.525161559 1.676966514 1.009007675 1 11.62420674 -5.372839032 3.251994715 0.958362235 1.603347749 0.962192416 0.057984125 0.031444751 0.624340699 0.008130713 0.019843488 4.24E-06 5.372839032 0.644985514 SQSS(ph)DTEQQSPTSGGGK ddPTM_HeLa_Curcumin_4h_R1 3 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 SQS(0.074)S(0.907)DT(0.019)EQQSPTSGGGK;SQS(0.003)S(0.954)DT(0.043)EQQSPTSGGGK;S(0.004)QS(0.078)S(0.915)DT(0.002)EQQSPTSGGGK ;; 339.46 8.69E-151 146444000 7440.9 6380.3 5986.1 6730.1 6565.9 9842.4 10371.4 17221.1 7891.3 6493 TRUE FALSE FALSE 6851.944913 6931.784702 6207.950132 6702.252629 6487.605931 7800.975293 10662.39357 22471.73411 7025.644133 6718.631267 1.019842382 1.031725723 0.923990302 0.997562206 0.965614226 1.161095911 1.586988949 3.344689301 1.045695746 1 12.71395164 -4.135147668 1.687221544 1.00238611 4.744353709 0.995479453 0.047216078 0.057996794 0.123512427 0.006676021 0.385674512 7.33E-05 4.135147668 3.741967599 up ANST(ph)SDSVFTETPSPVLK ddPTM_HeLa_Curcumin_4h_R1 2 ANSTSDSVFTETPSPVLK 18 0 C9JEZ4;Q9UKI2 C9JEZ4 CDC42EP3 Cdc42 effector protein 3 1 0 ANS(0.087)T(0.886)S(0.026)DS(0.001)VFTETPSPVLK;ANS(0.015)T(0.641)S(0.062)DS(0.282)VFTETPSPVLK ; 266.39 3.51E-53 92173000 4409 3218.9 5204.8 4846 4763 6302.6 7580.8 14913.3 4122.6 4061.7 TRUE FALSE FALSE 4060.022998 3497.127373 5397.694467 4825.948536 4706.204336 4995.369715 7793.496845 19460.29652 3670.361094 4202.843773 0.966018062 0.832085978 1.284295767 1.148257893 1.11976666 1.188568975 1.854338935 4.63026883 0.873304194 1 12.03715011 -4.133863713 1.755630389 1.017095472 6.760846996 0.985063458 0.132246092 0.102717173 0.23951349 0.018826509 1.084340972 7.35E-05 4.133863713 5.743751524 up S(ph)VT(ph)S(ph)HSS(ph)GDHVKK ddPTM_HeLa_Curcumin_4h_R1 1 SVTSHSSGDHVKK 13 1 E9PDR5;E7EPI0;Q9P2D0;H0Y9N7;Q9P2D0-3 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 4 0 S(0.996)VT(0.932)S(0.57)HS(0.57)S(0.932)GDHVKK 45.368 0.020384 15514000 2408.6 1863 2376.9 2494.8 2019.7 3012.2 1819.8 1736.9 2799.6 2220.2 TRUE FALSE FALSE 2217.956768 2024.029419 2464.990005 2484.477179 1995.616397 2387.435766 1870.85869 2266.472814 2492.490884 2297.351785 0.965440636 0.881027204 1.0729702 1.081452651 0.868659476 1.039212097 0.814354468 0.986558885 1.084940888 1 11.16575607 -4.774967934 24.99903917 0.984142958 0.900456627 0.164652532 0.083636125 258.1270145 476988.4918 0.009941397 0.030060179 1.68E-05 4.774967934 -0.083686331 S(ph)VTLEEAIAEQNESER ddPTM_HeLa_Curcumin_4h_R1 1 SVTLEEAIAEQNESER 16 0 Q6W2J9-4;Q6W2J9-2;Q6W2J9;H7C231;H7BYY2 Q6W2J9-4 BCOR BCL-6 corepressor 1 0 S(0.662)VT(0.338)LEEAIAEQNESER 248.1 7.59E-31 1789300 314.15 212.76 362.73 158.26 48.108 336.36 200.97 231.13 251.34 135.92 TRUE FALSE FALSE 289.284696 231.1500264 376.1730929 157.6051621 47.53434352 266.5951444 206.6086773 301.600473 223.7686308 140.6432099 2.056869267 1.643520697 2.674662312 1.120602709 0.337978233 1.895542235 1.469027033 2.144436786 1.59103757 1 7.135896092 S(ph)VTPPPPPR ddPTM_HeLa_Curcumin_4h_R1 1 SVTPPPPPR 9 0 O95835;O95835-2;H0YG09 O95835 LATS1 Serine/threonine-protein kinase LATS1 1 0 S(0.519)VT(0.481)PPPPPR 104.75 0.010847 37857000 3825.5 3623.6 4276.4 3637.3 4583.2 4920.4 2867.2 1684.3 4402.4 3575.6 TRUE FALSE FALSE 3522.707638 3936.807838 4434.887146 3622.249816 4528.548333 3899.853576 2947.645915 2197.835316 3919.467734 3699.851834 0.952121273 1.064044728 1.198666148 0.979025642 1.223980996 1.05405669 0.796692962 0.594033333 1.059358026 1 11.85325178 -4.534333159 3.047186117 1.020538183 0.608315499 0.719476222 0.093020073 0.124450629 2.182440176 0.01441295 0.090148368 2.92E-05 4.534333159 -0.412222684 S(ph)VTWPEEGK ddPTM_HeLa_Curcumin_4h_R1 1 SVTWPEEGK 9 0 Q96QC0 Q96QC0 PPP1R10 Serine/threonine-protein phosphatase 1 regulatory subunit 10 1 0 S(1)VTWPEEGK 119.22 0.0064363 8633100 1280.9 1061.3 1000.9 1194 1442.7 1508.8 1371.6 886.83 1299.8 973.95 TRUE FALSE FALSE 1179.515413 1153.034043 1037.994234 1189.059544 1425.496745 1195.857872 1410.083405 1157.220385 1157.215192 1007.79469 1.170392566 1.144116013 1.029965969 1.179862879 1.414471379 1.186608626 1.399177252 1.148269976 1.148264824 1 9.976986045 -5.997292787 23.86937964 1.085722971 1.289106415 0.484745788 0.091170228 29.96145947 264157.409 0.013907507 0.025091027 1.01E-06 5.997292787 0.203383444 S(ph)VVADTDQK ddPTM_HeLa_Curcumin_4h_R1 1 SVVADTDQK 9 0 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 0 S(1)VVADTDQK 107.11 0.010082 9588600 2018.2 1754.9 1835.2 2185.3 1992.1 2868.1 2467.8 2287.6 2079.6 1857.9 TRUE FALSE FALSE 1858.45734 1906.585736 1903.214126 2176.257808 1968.345509 2273.22373 2537.039826 2985.078709 1851.473083 1922.461887 0.966706988 0.991741761 0.989987963 1.1320161 1.023867117 1.182454511 1.319682769 1.552737524 0.963074012 1 10.90873928 -3.376995891 0.575894742 0.983357451 2.866587391 0.957363371 0.037832401 1.076039812 0.1161409 0.006611491 1.709362308 0.000419763 3.376995891 1.88322994 S(ph)VVDMDLDDTDDGDDNAPLFYQPGKR ddPTM_HeLa_Curcumin_4h_R1 1 SVVDMDLDDTDDGDDNAPLFYQPGKR 26 1 E7EMW7;O95071-2;O95071;E7ET84 E7EMW7 UBR5 E3 ubiquitin-protein ligase UBR5 1 0 S(0.649)VVDMDLDDT(0.351)DDGDDNAPLFYQPGKR 82.942 5.16E-05 21073000 3656.8 2493.5 2520.4 3031 2398.2 3697.2 2389.5 2494.1 4111.5 4165 TRUE FALSE FALSE 3367.360421 2709.027029 2613.808241 3018.458525 2369.603031 2930.359044 2456.542939 3254.539609 3660.478736 4309.73344 0.781338444 0.62858343 0.606489538 0.700381721 0.549825892 0.679939742 0.569998812 0.755160303 0.849351541 1 12.07338293 -8.107946335 0.644553428 0.984038772 0.628933358 0.67218257 0.075568023 0.181172495 0.168433575 0.027269527 0.016782464 7.80E-09 8.107946335 -0.355105415 S(ph)VVGTPAYLAPEVLR ddPTM_HeLa_Curcumin_4h_R1 2 SVVGTPAYLAPEVLR 15 0 O94806;F8WBA3;Q15139;H0Y5M6 O94806 PRKD3;PRKD1 Serine/threonine-protein kinase D3;Serine/threonine-protein kinase;Serine/threonine-protein kinase D1 1 0 S(0.998)VVGT(0.002)PAYLAPEVLR;S(0.975)VVGT(0.025)PAYLAPEVLR ; 205.28 1.66E-09 24166000 521.59 577.52 418.86 514.57 583.46 702.86 632.27 650.91 490.12 624 TRUE FALSE FALSE 480.3056011 627.4382554 434.3833201 512.4408457 576.5026206 557.0789131 650.0097945 849.3694626 436.3550622 645.6839536 0.743871051 0.97174206 0.672749133 0.793640361 0.892855734 0.862773358 1.006699626 1.315456978 0.67580286 1 9.334684364 -4.270662893 1.917644609 0.861708861 1.451895945 0.64067172 0.110165616 0.418733338 1.606818577 0.016394404 0.434729439 5.36E-05 4.270662893 0.590187085 VQDLSAGGQGS(ph)LTDSGPER ddPTM_HeLa_Curcumin_4h_R1 2 VQDLSAGGQGSLTDSGPER 19 0 P40222 P40222 TXLNA Alpha-taxilin 1 0 VQDLSAGGQGS(0.999)LT(0.001)DSGPER;VQDLS(0.069)AGGQGS(0.927)LT(0.004)DSGPER ; 169.43 6.01E-06 16852900 2010.85 1960.81 2022.8 2310.3 2514.79 3503.4 4047.8 9517 2373.59 2327.6 TRUE FALSE FALSE 1851.689101 2130.293679 2097.766747 2300.740591 2484.802772 2776.755349 4161.370374 12418.68949 2113.213115 2408.483927 0.768819372 0.884495701 0.870990553 0.95526508 1.031687504 1.152905908 1.727796614 5.156226849 0.877403869 1 11.23390958 -4.126328578 1.858419248 0.906152185 7.666556471 0.99352038 0.101725421 0.080643248 0.211428713 0.017778884 1.056420649 7.48E-05 4.126328578 6.760404287 up S(ph)VVSFDK ddPTM_HeLa_Curcumin_4h_R1 2 SVVSFDK 7 0 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 0 S(1)VVSFDK;S(0.984)VVS(0.016)FDK ; 141.52 0.0033713 137043000 15126.6 16960.1 15671.4 15616.6 18206.3 17373.6 17743.5 4974.8 13333.1 14870.4 TRUE FALSE FALSE 13929.31365 18426.05547 16252.19587 15551.98265 17989.20176 13770.11952 18241.33486 6491.593619 11870.49229 15387.14529 0.905256523 1.197496684 1.056219043 1.010712666 1.169105862 0.894910606 1.185491819 0.421884209 0.771455137 1 13.90943798 -4.250085966 24.91387687 1.002747871 0.421883853 0.644569177 0.132874899 695.659161 1526522.129 0.015660097 0.324922072 5.62E-05 4.250085966 -0.580864019 S(ph)WASPVYTEADGTFSR ddPTM_HeLa_Curcumin_4h_R1 4 SWASPVYTEADGTFSR 16 0 Q8WWI1-3;E9PMS6;E9PMP7;E9PJ10;E9PK58;E9PLU6 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 S(0.956)WAS(0.044)PVYTEADGTFSR;S(0.639)WAS(0.36)PVYT(0.001)EADGTFSR;S(1)WASPVYTEADGTFSR;S(0.998)WAS(0.002)PVYTEADGTFSR ;;; 288.06 1.95E-79 418106400 6191.07 5347.32 5025.96 5687.3 5813.34 8760.38 8479.45 5011.76 6410.34 5353.72 TRUE FALSE FALSE 5701.040277 5809.518514 5212.226499 5663.76746 5744.019717 6943.378438 8717.360546 6539.822553 5707.14174 5539.761372 1.02911297 1.048694722 0.940875635 1.022384735 1.036871326 1.253371395 1.573598565 1.180524235 1.030214364 1 12.43560812 -5.155810215 3.309934472 1.012358164 1.383613591 0.718090792 0.093607508 0.080414701 1.653840747 0.011534222 0.03268998 6.99E-06 5.155810215 0.371255427 S(ph)WDSSSPVDRPEPEAASPTTR ddPTM_HeLa_Curcumin_4h_R1 1 SWDSSSPVDRPEPEAASPTTR 21 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 S(0.925)WDS(0.025)S(0.025)S(0.025)PVDRPEPEAASPTTR 71.54 0.0012511 9636900 309.99 191.53 134.27 201.79 308.77 187.15 364.33 152.57 158.52 128.66 TRUE FALSE FALSE 285.4539644 208.0849998 139.2461643 200.9550464 305.0881194 148.3329804 374.5521193 199.0878907 141.1307526 133.1309254 2.144159695 1.56301024 1.045934022 1.50945429 2.291639741 1.114188758 2.81341182 1.49542933 1.060089924 1 7.056701928 -9.510182804 1.227806693 0.99484891 1.787705096 0.233418421 0.515139167 0.535758799 1.430560131 0.360730736 0.084733573 3.09E-10 9.510182804 0.792856186 S(ph)WEQT(ph)Y(ph)EEEIFLS(ph)S(ph)ELQEEVPTLSR ddPTM_HeLa_Curcumin_4h_R1 1 SWEQTYEEEIFLSSELQEEVPTLSR 25 0 K7EJC3;H0Y843;A4FU69-6;A4FU69-5;A4FU69-2;A4FU69-4;A4FU69-3;A4FU69 K7EJC3 EFCAB5 EF-hand calcium-binding domain-containing protein 5 5 0 S(0.999)WEQT(0.999)Y(0.999)EEEIFLS(0.987)S(0.988)ELQEEVPT(0.014)LS(0.014)R 42.612 0.0093135 0 567.62 273.13 372.69 362.55 537.12 593.71 520.24 358.96 516.8 483.5 TRUE FALSE FALSE 522.6922781 296.7381402 386.5022193 361.0498642 530.7151948 470.5678535 534.8365342 468.4052516 460.108333 500.301589 1.044754383 0.593118524 0.77253846 0.721664436 1.060790544 0.940568377 1.069028254 0.93624578 0.919661946 1 8.966654224 S(ph)WGEQCPETSGTDSGR ddPTM_HeLa_Curcumin_4h_R1 2 SWGEQCPETSGTDSGR 16 0 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 0 S(1)WGEQCPETSGTDSGR;S(1)WGEQCPETSGTDSGR ; 169.06 0.00014513 11651200 980.35 1002.09 955.15 1291.4 1570.08 1006.12 1064.97 663.33 1207.36 1121.55 TRUE FALSE FALSE 902.754263 1088.706194 990.5486992 1286.056529 1551.357821 797.4393707 1094.850192 865.5762634 1074.915629 1160.523779 0.777885192 0.938116232 0.853535892 1.108169046 1.336773834 0.687137468 0.943410391 0.745849658 0.926233179 1 10.18056037 -4.518782448 0.00254984 1.818242714 3.43E-06 0 0.180306391 1569142.38 685.275376 240245.1366 248462.9689 3.03E-05 4.518782448 -1.818239279 S(ph)WGQQAQEYQEQK ddPTM_HeLa_Curcumin_4h_R1 1 SWGQQAQEYQEQK 13 0 Q5VZK9;Q5VZK9-2 Q5VZK9 LRRC16A Leucine-rich repeat-containing protein 16A 1 0 S(0.999)WGQQAQEY(0.001)QEQK 123.1 0.0022212 8805300 888.35 904.16 1009.2 929.2 968.71 918.36 660.76 337.28 1002.5 781.36 TRUE FALSE FALSE 818.0361601 982.3115615 1046.60184 925.3552166 957.1587659 727.8817839 679.2991473 440.1151194 892.5282581 808.5122018 1.01177961 1.21496195 1.29447872 1.144516081 1.183851974 0.900273097 0.840184163 0.544351858 1.103914395 1 9.659125736 -4.440820087 1.507852646 1.063049131 0.456117556 0.725523793 0.109391052 0.415007618 1.108362059 0.01900247 0.336658442 3.62E-05 4.440820087 -0.606931575 S(ph)WHDVQVSSAYVK ddPTM_HeLa_Curcumin_4h_R1 2 SWHDVQVSSAYVK 13 0 O43399;O43399-5;O43399-7;A0A087WYR3 O43399 TPD52L2 Tumor protein D54 1 0 S(1)WHDVQVSSAYVK;S(0.979)WHDVQVS(0.02)S(0.001)AYVK ; 95.273 0.0044726 15465800 6161.8 4818.8 5110.8 5318.1 5578.8 7408.7 4927 5859.7 7475.6 5819.4 TRUE FALSE FALSE 5674.087028 5235.3156 5300.210744 5296.095111 5512.276454 5872.052107 5065.23836 7646.295555 6655.545383 6021.623717 0.94228522 0.869419254 0.880196271 0.879512796 0.915413635 0.975160917 0.841174839 1.269806271 1.105274208 1 12.55593684 -4.250250979 24.92550208 0.9427245 1.269806469 0.646332373 0.074224383 675.1820329 1504140.593 0.008658972 0.177235192 5.62E-05 4.250250979 0.327081969 S(ph)WSPPPEVSR ddPTM_HeLa_Curcumin_4h_R1 2 SWSPPPEVSR 10 0 Q9NR19;Q9NR19-2;F8WCJ4;C9JXD9;C9IYL0;B4DEH9;C9JY31 Q9NR19 ACSS2 "Acetyl-coenzyme A synthetase, cytoplasmic" 1 0 S(0.5)WS(0.5)PPPEVS(0.001)R;S(0.99)WS(0.01)PPPEVSR ; 104.07 0.01016 253129000 5959.4 5148.4 5221.2 5688.9 5360.5 6095.6 4930.3 4502.2 5785 5277.9 TRUE FALSE FALSE 5487.707202 5593.404755 5414.702265 5665.360839 5296.579539 4831.303848 5068.630949 5874.900054 5150.399973 5461.306632 1.004834112 1.024188007 0.991466444 1.037363624 0.969837421 0.884642481 0.928098583 1.075731588 0.943071012 1 12.41503045 -5.53996521 20.54116199 1.005378539 0.953999754 0.094069552 0.050775764 33.35988828 40104.50667 0.00640117 0.012809541 2.88E-06 5.53996521 -0.051378785 S(ph)WSTATSPLGGERPFR ddPTM_HeLa_Curcumin_4h_R1 2 SWSTATSPLGGERPFR 16 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0;H0Y8P3;Q9UPQ0-2;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46;D6RJ93;Q6NVB9 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 S(1)WSTATSPLGGERPFR;S(1)WSTATSPLGGERPFR ; 135.69 0.00018631 41447000 2498 2105.61 2165.32 2069.07 2379.06 2753.07 2239.35 1796.68 2313.47 2294.79 TRUE FALSE FALSE 2300.280664 2287.609546 2245.568664 2060.508737 2350.691263 2182.052249 2302.180134 2344.479461 2059.688129 2374.533782 0.968729391 0.963393136 0.945688236 0.867752968 0.989959074 0.918939231 0.969529325 0.987343065 0.867407381 1 11.21342857 -7.915525014 0.848987274 0.994130345 0.946555068 0 0.052323213 0.520198951 0.809894023 0.009952371 0.007930424 1.21E-08 7.915525014 -0.047575277 DLPPFGINS(ph)PQALKK ddPTM_HeLa_Curcumin_4h_R1 2 DLPPFGINSPQALKK 15 1 A0A2R8YGD3;Q9Y4G8;A0A2R8Y661;H0Y8H7 A0A2R8YGD3 RAPGEF2 Rap guanine nucleotide exchange factor 2 1 0 DLPPFGINS(1)PQALKK;DLPPFGINS(1)PQALKK ; 89.913 0.0036329 101790000 8008.9 5936 7856.4 8004.6 7535.9 8044.2 5175 1593.17 7551.9 6158.8 TRUE FALSE FALSE 7374.987114 6449.08139 8147.565095 7971.479086 7446.039314 6375.742243 5320.196572 2078.920199 6723.475464 6372.817842 1.157256852 1.011967006 1.278487052 1.250856259 1.168406112 1.000458887 0.834826399 0.326216793 1.055023952 1 12.63771571 -4.244601207 1.56965227 1.10470458 0.010914816 0.875267196 0.091914798 0.324953051 0.714503724 0.015565842 0.550587053 5.69E-05 4.244601207 -1.093789765 down S(ph)Y(ph)RIIRGNEAGRFR ddPTM_HeLa_Curcumin_4h_R1 1 SYRIIRGNEAGRFR 14 3 Q6V0I7-3;Q6V0I7 Q6V0I7-3 FAT4 Protocadherin Fat 4 2 0 S(1)Y(1)RIIRGNEAGRFR 78.529 0.0086382 14317000 3295.3 2729.3 2977.4 3409.7 3223 3912.9 3081.2 3034.3 3553.7 3070.2 TRUE FALSE FALSE 3034.473528 2965.20853 3087.745063 3395.591565 3184.56783 3101.320433 3167.650179 3959.444102 3163.868001 3176.889221 0.955171338 0.933368564 0.971939796 1.068841665 1.002417021 0.976212961 0.997091796 1.246327406 0.995901267 1 11.63339907 -4.261105611 4.78950454 0.982728786 1.261139544 0.83637391 0.03410385 0.054701156 3.558106097 0.005114269 0.050612845 5.48E-05 4.261105611 0.278410758 APS(ph)DSS(ph)LGTPSDGRPELR ddPTM_HeLa_Curcumin_4h_R1 1 APSDSSLGTPSDGRPELR 18 1 M0R0F9;W4VSQ9;Q15642-4;Q15642-2;Q15642-3;Q15642;M0R2H7;Q15642-5 M0R0F9 TRIP10 Cdc42-interacting protein 4 2 0 APS(0.998)DS(0.225)S(0.742)LGT(0.012)PS(0.022)DGRPELR 84.66 0.0034653 331170000 3974.9 3617.5 3864.5 4636.6 4418.9 4699.4 3013.7 822.91 4467.2 3998.7 TRUE FALSE FALSE 3660.282471 3930.180581 4007.72177 4617.414978 4366.207504 3724.691467 3098.256311 1073.811471 3977.159336 4137.654527 0.884627377 0.949857112 0.968597485 1.115949857 1.055237327 0.900193924 0.748795312 0.259521781 0.96121107 1 12.01459748 -4.244426182 1.779068764 0.965540404 0.003182014 0.922177517 0.063769934 0.218278211 0.657370008 0.011108076 0.357342106 5.70E-05 4.244426182 -0.962358389 down S(ph)YDVPPPPMEPDHPFYSNISK ddPTM_HeLa_Curcumin_4h_R1 6 SYDVPPPPMEPDHPFYSNISK 21 0 P18669;Q8N0Y7 P18669 PGAM1;PGAM4 Phosphoglycerate mutase 1;Probable phosphoglycerate mutase 4 1 0 S(0.986)Y(0.014)DVPPPPMEPDHPFYSNISK;S(0.996)Y(0.004)DVPPPPMEPDHPFYSNISK;S(0.986)Y(0.014)DVPPPPMEPDHPFYSNISK;S(0.921)Y(0.079)DVPPPPMEPDHPFYSNISK;S(0.981)Y(0.019)DVPPPPMEPDHPFYSNISK;S(0.969)Y(0.031)DVPPPPMEPDHPFYSNISK ;;;;; 120.44 8.38E-06 1140080000 19062.1 15339 16978.8 16945.3 19019.3 24905.1 18907.2 17128.6 21516.6 17531.7 TRUE FALSE FALSE 17553.31467 16664.83481 17608.04926 16875.18484 18792.50727 19739.50152 19437.68515 22351.03129 19156.28281 18140.92527 0.967608565 0.918632019 0.970625754 0.93022735 1.035917793 1.088119885 1.071482565 1.2320778 1.055970549 1 14.14696042 -4.051559875 0.780959173 0.9753312 1.437401771 0.755700532 0.043437284 1.030580098 0.361687841 0.006134771 0.445885138 8.88E-05 4.051559875 0.462070571 S(ph)YEDLTESEDGAASGDSHK ddPTM_HeLa_Curcumin_4h_R1 2 SYEDLTESEDGAASGDSHK 19 0 A0A0A0MSQ9;Q86VX9-5;Q86VX9 A0A0A0MSQ9 MON1A Vacuolar fusion protein MON1 homolog A 1 0 S(0.803)YEDLT(0.197)ESEDGAASGDSHK;S(0.997)YEDLT(0.003)ESEDGAASGDSHK ; 298.09 1.64E-84 55831000 7022.8 6060.2 5963.7 7204.1 8303.2 8176.5 5754.9 4858.4 7562.2 6449.8 TRUE FALSE FALSE 6466.93797 6584.016684 6184.719968 7174.291343 8204.189763 6480.601732 5916.367005 6339.703795 6732.64558 6673.93007 0.968984976 0.98652767 0.926698348 1.074972508 1.229289141 0.97103231 0.886489212 0.949920621 1.008797741 1 12.70432085 -6.259089498 24.98495443 0.981089439 1.02344011 0.059527619 0.087290606 605.5747212 6438738.69 0.01409262 0.022648719 5.51E-07 6.259089498 0.04235067 S(ph)YEQVPPQGFTSR ddPTM_HeLa_Curcumin_4h_R1 1 SYEQVPPQGFTSR 13 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 0 S(0.999)YEQVPPQGFTSR 83.856 0.01838 6062200 2133.1 1511 1980 1931.7 1733.5 2054.9 1202.3 948.44 2303.7 1952.1 TRUE FALSE FALSE 1964.262884 1641.604107 2053.380542 1923.707137 1712.829145 1628.690577 1236.033302 1237.61499 2050.989874 2019.93533 0.972438501 0.812701319 1.016557566 0.952360756 0.847962368 0.806308278 0.611917265 0.612700304 1.015374029 1 10.98009339 -4.95851686 0.898719995 0.976836191 0.533127205 0.834335102 0.059979525 0.25731731 0.279264179 0.009434014 0.088147326 1.10E-05 4.95851686 -0.443708985 S(ph)YERAQKEGSIAMQS(ph)SAT(ph)HLT(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 SYERAQKEGSIAMQSSATHLTSK 23 2 E9PKB1;Q0P6D6 E9PKB1 CCDC15 Coiled-coil domain-containing protein 15 4 0 S(0.52)Y(0.45)ERAQKEGS(0.086)IAMQS(0.727)S(0.253)AT(0.576)HLT(0.841)S(0.547)K 40.097 0.0089294 0 916.3 502.23 918.76 1031.4 662.04 796.11 738.66 608.17 803.44 655.53 TRUE FALSE FALSE 843.7738881 545.6405233 952.8100538 1027.13234 654.1456054 630.987812 759.3848116 793.5982333 715.3046421 678.3096187 1.243936198 0.804412186 1.404683094 1.514252948 0.964376131 0.930235684 1.119525348 1.169964588 1.054540025 1 9.405800141 -4.260615031 17.52189746 1.12035445 1.169965213 0.00568473 0.207456639 10.02000321 209423.2784 0.029010144 0.230703649 5.49E-05 4.260615031 0.049610763 S(ph)YESANGR ddPTM_HeLa_Curcumin_4h_R1 1 SYESANGR 8 0 Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383 Q96HJ9-2 LUC7L2 Putative RNA-binding protein Luc7-like 2 1 0 S(0.997)YES(0.003)ANGR 125.68 0.0065 10006000 1533 2457.6 1630.6 1652.1 1499.9 1574.1 922.47 945.89 1433.5 1752.8 TRUE FALSE FALSE 1411.661432 2670.023993 1691.03147 1645.264048 1482.014672 1247.613916 948.3520255 1234.287507 1276.248636 1813.70967 0.778328228 1.472134178 0.932360619 0.907126469 0.81711792 0.687879619 0.522879732 0.680532021 0.703667548 1 10.82472782 -5.377096563 1.808029833 0.945611451 0.600960672 0.37286602 0.195467187 0.306965589 1.928890267 0.029048907 0.08711591 4.20E-06 5.377096563 -0.344650779 PAS(ph)PSLQLLPWR ddPTM_HeLa_Curcumin_4h_R1 2 PASPSLQLLPWR 12 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 0 PAS(0.909)PS(0.091)LQLLPWR;PAS(0.85)PS(0.15)LQLLPWR ; 157.5 0.00028733 133516000 2070.84 1615.65 1697.88 1559.02 1513 1992.74 1256.56 332.9 1335.81 1392.18 TRUE FALSE FALSE 1906.930829 1755.299587 1760.804926 1552.569188 1494.958463 1579.423261 1291.815692 434.3996775 1189.274985 1440.558151 1.32374443 1.218485755 1.222307426 1.077755304 1.037763357 1.09639674 0.896746647 0.301549561 0.825565413 1 10.49241218 -4.244395002 1.647208902 1.153103848 1.92E-15 0.748437694 0.137142745 0.345337618 0.856079275 0.018713662 0.639814074 5.70E-05 4.244395002 -1.153103848 down S(ph)YSPDGK ddPTM_HeLa_Curcumin_4h_R1 2 SYSPDGK 7 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 0 S(0.872)YS(0.128)PDGK;S(0.993)YS(0.007)PDGK ; 117.81 0.013179 556480000 15152.8 22474.1 17159.7 13780.1 15601.2 14417.8 10768.3 7911 10939 14315.9 TRUE FALSE FALSE 13953.43989 24416.66106 17795.65358 13723.0816 15415.16588 11427.38576 11070.42952 10323.02748 9739.019068 14813.37646 0.941948645 1.648284652 1.201323252 0.926397951 1.04062473 0.771423435 0.74732655 0.696872014 0.657447618 1 13.8546129 -5.212118602 2.583573519 1.04400438 0.720887075 0.274588048 0.238325959 0.297380537 3.868253773 0.032519546 0.09533107 6.14E-06 5.212118602 -0.323117305 S(ph)YTLVVAK ddPTM_HeLa_Curcumin_4h_R1 3 SYTLVVAK 8 0 O43491;O43491-4;E9PHY5;E9PK52;O43491-3;O43491-2;E9PII3;A0A2R8Y5B3;E9PJP4;E9PQD2;E9PIG0;E9PRG1;E9PQN0 O43491 EPB41L2 Band 4.1-like protein 2 1 0 S(1)YTLVVAK;S(1)YTLVVAK;S(0.999)YT(0.001)LVVAK ;; 176.38 0.0011395 120269500 5203 3472.05 4625.3 4017.7 4695.6 10955.4 9998.3 6874.5 5825.8 5343.1 TRUE FALSE FALSE 4791.17706 3772.158531 4796.717687 4001.075822 4639.608037 8683.126547 10278.82539 8970.503404 5186.724315 5528.772327 0.866589683 0.682277784 0.867591827 0.723682508 0.839175094 1.570534295 1.859151504 1.622512716 0.938133099 1 12.43274345 -5.186974079 4.116996757 0.888123182 1.732195106 0.9235261 0.11059741 0.0494614 1.605916878 0.018016522 0.048204158 6.50E-06 5.186974079 0.844071924 S(ph)YVTTSTR ddPTM_HeLa_Curcumin_4h_R1 1 SYVTTSTR 8 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 0 S(0.853)YVT(0.029)T(0.118)STR 148.69 0.0020858 215360000 1850.8 1210.3 1549.2 1912.3 1850.2 1934.6 1940.4 1888.7 1617.6 1408.9 TRUE FALSE FALSE 1704.307227 1314.912939 1606.614715 1904.387409 1828.137573 1533.342153 1994.842402 2464.555935 1440.153327 1457.85917 1.169047918 0.901947847 1.102036978 1.30629038 1.253987773 1.051776594 1.368336834 1.690530873 0.987854902 1 10.50963565 -1 0.597729106 1.077719117 38.68841593 0.723375373 0.116032379 64.08051583 0.460264032 0.021444373 3155.325557 0.1 1 37.61069681 SAADS(ph)ISESVPVGPK ddPTM_HeLa_Curcumin_4h_R1 1 SAADSISESVPVGPK 15 0 P45974-2;P45974 P45974-2 USP5 Ubiquitin carboxyl-terminal hydrolase 5 1 0 S(0.036)AADS(0.58)IS(0.29)ES(0.094)VPVGPK 122.63 0.0011254 22994000 5086.1 4178.5 4933.9 5213.6 5550.3 8330.7 6600 5193.8 5235.4 5213.6 TRUE FALSE FALSE 4683.529818 4539.670921 5116.754674 5192.027505 5484.116298 6602.818914 6785.178237 6777.365711 4661.089718 5394.772212 0.868160811 0.841494458 0.94846538 0.962418301 1.016561234 1.22392914 1.25773211 1.256283944 0.86400121 1 12.39734633 -5.345568818 1.947903199 0.929689759 1.263692851 0.908662195 0.047003059 0.091820648 0.669473305 0.008821541 0.026133739 4.51E-06 5.345568818 0.334003093 SAADSISES(ph)VPVGPK ddPTM_HeLa_Curcumin_4h_R1 1 SAADSISESVPVGPK 15 0 P45974-2;P45974 P45974-2 USP5 Ubiquitin carboxyl-terminal hydrolase 5 1 0 S(0.001)AADS(0.077)IS(0.223)ES(0.7)VPVGPK 104.81 0.004025 0 1180.3 939.51 988.41 1226.1 1354.9 1438.2 1108 989.68 1413.3 1066.5 TRUE FALSE FALSE 1086.87801 1020.717058 1025.041344 1221.026723 1338.743702 1139.901108 1139.087498 1291.428876 1258.264526 1103.560796 0.984882767 0.924930518 0.928849002 1.106442643 1.213112778 1.03293005 1.032192791 1.170238089 1.140185961 1 10.1079504 -6.244266741 23.60484661 0.982139977 1.107943618 0.358144398 0.07597797 241.4735995 331919.7938 0.008772162 0.014517851 5.70E-07 6.244266741 0.125803642 AVTGQTTQVS(ph)PPVIAGR ddPTM_HeLa_Curcumin_4h_R1 2 AVTGQTTQVSPPVIAGR 17 0 Q6MZP7;Q6MZP7-3 Q6MZP7 LIN54 Protein lin-54 homolog 1 0 AVTGQT(0.22)T(0.22)QVS(0.561)PPVIAGR;AVTGQTTQVS(1)PPVIAGR ; 150.9 8.34E-09 4366300 1358.39 1454.17 1090.23 1320.75 1285.05 1795.71 1716.57 2163.4 1510.96 1250.43 TRUE FALSE FALSE 1250.871998 1579.861975 1130.634883 1315.285086 1269.726618 1423.259504 1764.732334 2823.010701 1345.211468 1293.882349 0.966758685 1.221024443 0.87383129 1.016541486 0.981330813 1.099991436 1.36390479 2.181814059 1.039670623 1 10.33749073 -4.124671039 1.469780174 0.995520121 2.965223187 0.945232534 0.084467102 0.224255221 0.340239175 0.011258432 0.704830279 7.50E-05 4.124671039 1.969703066 up SAALS(ph)IT(ph)VPS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 1 SAALSITVPSPQR 13 0 Q6ZV56-3 Q6ZV56-3 3 0 S(0.041)AALS(0.959)IT(1)VPS(1)PQR 64.52 0.0089716 0 963.1 1109.5 1209.3 1016.1 1268 1600.6 463.04 259.59 1500.7 1265.7 TRUE FALSE FALSE 886.8696187 1205.400236 1254.117722 1011.895647 1252.879928 1268.617518 476.0316562 338.737796 1336.076965 1309.682981 0.677163582 0.920375582 0.957573505 0.772626401 0.956628395 0.96864473 0.363470903 0.258641061 1.020152956 1 10.35500192 -4.708389679 6.110262297 0.866430734 0.295816427 0.823190004 0.109579564 0.07127172 5.648726117 0.018288336 0.069353373 1.96E-05 4.708389679 -0.570614307 SAAQAAAQT(ph)NSNAAGK ddPTM_HeLa_Curcumin_4h_R1 1 SAAQAAAQTNSNAAGK 16 0 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 0 SAAQAAAQT(0.716)NS(0.284)NAAGK 137.73 0.00014693 0 256.44 0 253.09 248.12 184.26 207.76 234.57 303.06 463.56 341.63 TRUE FALSE FALSE 236.1425034 0 262.469738 247.0933452 182.0628198 164.6682341 241.1514029 395.4615989 412.7086278 353.5016171 0.668009684 0 0.742485254 0.698987878 0.515026837 0.465820313 0.682179066 1.118698133 1.167487241 1 8.465573004 -8.651541412 1.0425553 0.963349107 0.601862492 0.300557482 0.273020691 0.49894112 1.092819685 0.098687972 0.052127111 2.23E-09 8.651541412 -0.361486616 SAAQAAAQTNS(ph)NAAGK ddPTM_HeLa_Curcumin_4h_R1 2 SAAQAAAQTNSNAAGK 16 0 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 0 SAAQAAAQT(0.031)NS(0.969)NAAGK;SAAQAAAQT(0.001)NS(0.999)NAAGK ; 102.03 0.0023821 10004300 4091.7 3011.09 3610.4 3857.7 3366.37 4659 3963.9 5431.7 4198.3 3630.5 TRUE FALSE FALSE 3767.837627 3271.355202 3744.2046 3841.73786 3326.228236 3692.670882 4075.116366 7087.800326 3737.756994 3756.659605 1.002975522 0.870814912 0.996684553 1.022647315 0.885421781 0.98296659 1.084771258 1.886729454 0.99496824 1 11.87523468 -4.255449512 3.433728848 0.984694129 2.006970054 0.967305519 0.050211738 0.038524649 0.757907931 0.007079067 0.103200114 5.55E-05 4.255449512 1.022275926 SAAQAAAQTNSNAAGK ddPTM_HeLa_Curcumin_4h_R1 2 SAAQAAAQTNSNAAGK 16 0 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 0 ; ; 298.78 6.16E-113 10193000 6921 5358.8 5467.2 6129.9 5707.4 7205.2 5267.1 5416 6420.6 5185.3 FALSE FALSE TRUE 6373.195547 5821.990794 5669.819241 6104.536098 5639.342983 5710.760301 5414.88065 7067.313468 5716.276244 5365.488789 1.187812667 1.085081159 1.056719987 1.13774091 1.051039934 1.06435043 1.009205473 1.317179803 1.065378471 1 12.38949389 -9.605175639 1.418481633 1.000249239 1.116143834 0.110115445 0.085132452 0.520534892 1.886197673 0.056700062 0.013200075 2.48E-10 9.605175639 0.115894594 SAAQAAAQTNSNAAGK(ac)QLR ddPTM_HeLa_Curcumin_4h_R1 2 SAAQAAAQTNSNAAGKQLR 19 1 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 1 ; SAAQAAAQTNSNAAGK(1)QLR;SAAQAAAQTNSNAAGK(1)QLR 418.8 0 6253800 854.06 1048.83 809.84 691.33 794.12 1276.3 1006.07 1263.84 882.35 916.21 FALSE TRUE FALSE 786.4602498 1139.486192 839.8533828 688.4694596 784.6506377 1011.580993 1034.297617 1649.178998 785.5584125 948.0482293 0.829557216 1.201928506 0.885876221 0.726196662 0.82764844 1.067014274 1.090975738 1.739551794 0.828605959 1 9.888816644 -3.98751159 1.46723465 0.919772683 2.599104023 0.786155653 0.128545482 0.803932781 0.930820198 0.019066087 2.378980419 0.000102917 3.98751159 1.67933134 SAAS(ph)PVVSSMPER ddPTM_HeLa_Curcumin_4h_R1 2 SAASPVVSSMPER 13 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 0 S(0.001)AAS(0.996)PVVS(0.001)S(0.002)MPER;SAAS(0.988)PVVS(0.012)SMPER ; 98 0.0094076 63976000 7157.9 5474.5 5902.3 6166.5 6292.6 7066.9 6604.3 2453 6988.1 5545.5 TRUE FALSE FALSE 6591.344662 5947.691386 6121.04443 6140.984657 6217.564855 5601.14528 6789.598883 3200.908408 6221.522913 5738.205712 1.148676955 1.036507174 1.066717496 1.07019249 1.083538159 0.976114409 1.183226818 0.557823921 1.084227932 1 12.48638397 -4.253553116 24.95026702 1.06930241 0.557823665 0.874113992 0.058544315 269.3179064 852037.6648 0.009014981 0.132766147 5.58E-05 4.253553116 -0.511478744 SAAVETASLS(ph)PSLVPAR ddPTM_HeLa_Curcumin_4h_R1 1 SAAVETASLSPSLVPAR 17 0 Q2KHT3-3;Q2KHT3 Q2KHT3-3 CLEC16A Protein CLEC16A 1 0 S(0.001)AAVETAS(0.003)LS(0.771)PS(0.225)LVPAR 281.68 7.37E-66 25972000 1981.3 1587.2 1803 2106.9 2026.5 2261.1 1664.2 1839.8 2104 1739.9 TRUE FALSE FALSE 1824.478014 1724.390496 1869.820766 2098.182206 2002.335311 1792.122372 1710.892973 2400.746551 1873.196464 1800.361395 1.013395432 0.957802417 1.038580793 1.165422793 1.112185207 0.995423684 0.950305298 1.333480354 1.040455804 1 10.81407082 -6.51356889 22.35233973 1.002640661 1.096618508 0.209978373 0.098127939 141.1274684 338837.2643 0.014285096 0.020883677 3.07E-07 6.51356889 0.093977846 SACGVCPGR ddPTM_HeLa_Curcumin_4h_R1 2 SACGVCPGR 9 0 P49207 P49207 RPL34 60S ribosomal protein L34 0 0 ; ; 148.04 6.33E-06 10159800 3390.6 3465 3289.5 3171.4 3254.1 3694.9 3057.5 2859.7 3815.4 3065.1 FALSE FALSE TRUE 3122.230432 3764.49916 3411.411764 3158.277587 3215.296983 2928.53609 3143.285221 3731.609366 3396.860166 3171.611997 0.984430137 1.186935591 1.075608166 0.9957957 1.013773748 0.923358876 0.99106865 1.176565535 1.07102009 1 11.63100057 SADAGSFS(ph)PTPGQIGGAVK ddPTM_HeLa_Curcumin_4h_R1 1 SADAGSFSPTPGQIGGAVK 19 0 O00443 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 0 SADAGS(0.005)FS(0.984)PT(0.011)PGQIGGAVK 217.35 2.25E-18 7304800 2192.1 1708.1 1824.6 1762.1 1410.2 1343.5 1441.5 6272.2 2076.7 1823.2 TRUE FALSE FALSE 2018.592972 1855.740553 1892.221281 1754.808897 1393.384286 1064.842956 1481.94461 8184.564906 1848.891206 1886.556064 1.06998833 0.983665732 1.003002941 0.930165252 0.738586206 0.564437483 0.785529059 4.338362936 0.980035124 1 10.88153926 -4.259662266 24.99953681 0.958263434 4.338364067 0.976912939 0.15853367 18.79618967 264393.0687 0.025834862 0.222705529 5.50E-05 4.259662266 3.380100633 SADAGSQKDS(ph)DDSAATPQDETVEER ddPTM_HeLa_Curcumin_4h_R1 1 SADAGSQKDSDDSAATPQDETVEER 25 1 E7EPJ7;O75962-5;O75962-4;O75962;E7EWP2;O75962-2;A0A1W2PRD7 E7EPJ7 TRIO Triple functional domain protein 1 0 S(0.039)ADAGS(0.023)QKDS(0.918)DDS(0.02)AAT(0.001)PQDETVEER 64.686 0.00086038 10277000 1018.8 704.8 867.36 909.14 788.12 781.32 518.08 353.03 1073.7 753.29 TRUE FALSE FALSE 938.160905 765.7197715 899.5051246 905.3782196 778.7221837 619.2654247 532.6159305 460.6672218 955.9177963 779.4667714 1.203593199 0.982363584 1.154000603 1.161535363 0.999044747 0.794473154 0.683308064 0.591003028 1.226374018 1 9.606343712 -5.122035335 1.706006841 1.098245142 0.618568658 0.861867106 0.078706182 0.114162431 0.619971051 0.012900093 0.051357646 7.55E-06 5.122035335 -0.479676484 SADGVIVSGVKDVDDFFEHER ddPTM_HeLa_Curcumin_4h_R1 1 SADGVIVSGVKDVDDFFEHER 21 1 G3V5X9;Q9UNH7;A0A0A0MRI2;Q9UNH7-2 G3V5X9 SNX6 "Sorting nexin-6;Sorting nexin-6, N-terminally processed" 0 0 67.928 0.0017026 3449000 2467.9 1907.1 2175.8 2178.5 1847.8 3035 2406.9 2163.3 3048.2 2618.4 FALSE FALSE TRUE 2272.563111 2071.941226 2256.437062 2169.485944 1825.766192 2405.506789 2474.431136 2822.880211 2713.820086 2709.389205 0.838773221 0.764726316 0.832821308 0.800728792 0.673866342 0.887840988 0.91328006 1.041888041 1.00163538 1 11.40375194 -9.020768786 0.882804626 0.997167033 0.839104549 0.312731638 0.091703978 0.588332601 0.854880405 0.057045426 0.018752297 9.53E-10 9.020768786 -0.158062483 SADTLWDIQK ddPTM_HeLa_Curcumin_4h_R1 2 SADTLWDIQK 10 0 A0A5F9ZHM4;P07195 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain 0 0 ; ; 167.12 2.57E-12 6047500 8150.9 5422.7 6471.8 5908.1 6425.6 7405.9 5246.3 4570.3 6711 6162.9 FALSE FALSE TRUE 7505.747664 5891.414025 6711.650601 5883.653848 6348.978917 5869.832858 5393.497058 5963.763431 5974.82009 6377.060316 1.176991794 0.923844802 1.052467794 0.922627913 0.995596498 0.920460615 0.845765414 0.935190062 0.936923879 1 12.63867581 -6.323006803 0.994891917 1.077977266 0.90649729 0.133123566 0.081040132 0.370216308 0.726782566 0.015205837 0.03109772 4.75E-07 6.323006803 -0.171479976 SADTLWGIQK ddPTM_HeLa_Curcumin_4h_R1 1 SADTLWGIQK 10 0 P00338;P00338-3;P00338-4 P00338 LDHA L-lactate dehydrogenase A chain 0 0 152.81 1.62E-08 3227600 3582.1 2615.4 2571.1 2344.2 2923.6 3706.8 2307.1 2485.3 2301.2 3028.6 FALSE FALSE TRUE 3298.573005 2841.463522 2666.387228 2334.500322 2888.737979 2937.967896 2371.831017 3243.056529 2048.764117 3133.843625 1.052564646 0.906702396 0.850836081 0.744931975 0.921787532 0.937496649 0.756844087 1.034849507 0.653754419 1 11.61371748 -7.135534481 4.223316995 1.024658149 0.868948212 0 0.142300331 0.151092407 4.512377281 0.012780175 0.015778438 7.32E-08 7.135534481 -0.155709937 SADVS(ph)PTTEGVK ddPTM_HeLa_Curcumin_4h_R1 2 SADVSPTTEGVK 12 0 A0A0J9YX34;Q9C040;Q9C040-2 A0A0J9YX34 TRIM2 Tripartite motif-containing protein 2 1 0 SADVS(0.998)PT(0.002)TEGVK;SADVS(0.921)PT(0.06)T(0.019)EGVK ; 211.22 1.24E-09 102903000 9279.1 8005 7745.9 8980.5 8274.4 9646.5 7415.6 8310 9369.4 8099 TRUE FALSE FALSE 8544.649444 8696.91653 8032.969868 8943.341071 8175.733184 7645.707162 7623.661778 10843.68075 8341.600261 8380.439647 1.019594413 1.037763757 0.958538001 1.067168484 0.975573303 0.912327692 0.909697116 1.293927431 0.995365472 1 13.03281022 -4.250724942 24.99631597 0.998121262 1.293927598 0.77717757 0.049056993 577.8973179 1348184.013 0.006907237 0.13511227 5.61E-05 4.250724942 0.295806336 SAEAELQSK ddPTM_HeLa_Curcumin_4h_R1 1 SAEAELQSK 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 104.42 0.0054415 3402500 2971.5 2632.3 2715.6 2653.8 2569 2862.3 2344.4 1945.8 2868.8 2312.1 FALSE FALSE TRUE 2736.302639 2859.824283 2816.242525 2642.819279 2538.366353 2268.626715 2410.177554 2539.065463 2554.099817 2392.445303 1.143726311 1.195356182 1.177139775 1.104651912 1.060992429 0.948246011 1.007411769 1.061284644 1.06756874 1 11.22427023 -5.490390836 7.878547342 1.091169663 1.005422485 0.362615997 0.060377148 0.340686094 72.27415813 0.01150575 0.02532521 3.23E-06 5.490390836 -0.085747178 SSGAPQDSDSSATCS(ph)ADEVDEAEGGDKNR ddPTM_HeLa_Curcumin_4h_R1 2 SSGAPQDSDSSATCSADEVDEAEGGDKNR 29 1 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 SSGAPQDSDS(0.007)S(0.093)AT(0.158)CS(0.741)ADEVDEAEGGDKNR;SSGAPQDSDS(0.004)S(0.086)AT(0.14)CS(0.77)ADEVDEAEGGDKNR ; 168.45 2.50E-16 88424000 3283.5 2529.6 2822.9 3184.5 3125.3 3079.1 2227.4 697.22 3265.1 2970 TRUE FALSE FALSE 3023.60751 2748.247352 2927.519157 3171.323383 3088.032839 2440.459951 2289.894849 909.7991684 2906.926699 3073.207279 0.983860585 0.894260329 0.952594111 1.031926289 1.004824133 0.794108477 0.745115653 0.296042241 0.945893471 1 11.58552936 -4.242925684 1.196727214 0.984607322 5.14E-17 0.933048243 0.054149429 0.257819378 0.292978411 0.007700309 0.318043923 5.72E-05 4.242925684 -0.984607322 down SAEDLDLLNAS(ph)FQDESK ddPTM_HeLa_Curcumin_4h_R1 2 SAEDLDLLNASFQDESK 17 0 J3KQV8;O43426;A0A0D9SGJ6;C9JFZ1;O43426-4;O43426-2;J3KPK1 J3KQV8 SYNJ1 Synaptojanin-1 1 0 SAEDLDLLNAS(1)FQDESK;SAEDLDLLNAS(0.996)FQDES(0.004)K ; 173.98 3.98E-18 0 2500.09 1815.39 2765.17 2669.18 2090.6 3367.1 2115.88 969.23 2400.69 2887.25 TRUE FALSE FALSE 2302.205238 1972.304222 2867.649633 2658.13564 2065.67096 2668.725505 2175.245898 1264.743765 2137.340313 2987.581723 0.770591553 0.660167455 0.959856466 0.889728177 0.691419065 0.893272805 0.728095865 0.423333613 0.71540815 1 11.54476246 -13.52287875 0.037877949 2.230527095 2.05E-10 0.098746549 0.153525994 616.7031719 1.867273403 92.94277984 32.0279597 3.00E-14 13.52287875 -2.230527095 SAEEEAADLPTK(ac)PTK ddPTM_HeLa_Curcumin_4h_R1 1 SAEEEAADLPTKPTK 15 1 Q8WW12;Q8WW12-2 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 0 1 SAEEEAADLPTK(1)PTK 264.28 1.87E-76 4103600 2822.2 2360.2 2144.6 2217.8 2172 2848 2142.6 2999.8 2246.4 1910.5 FALSE TRUE FALSE 2598.819892 2564.205171 2224.080763 2208.623331 2146.100319 2257.292696 2202.715589 3914.425211 1999.97554 1976.889733 1.314600328 1.297090641 1.125040373 1.117221307 1.085594347 1.141840467 1.114232905 1.980092843 1.011677843 1 10.94901669 -4.259886778 24.97436307 1.15121088 1.98009312 0.867571215 0.098950555 43.55535622 700542.4151 0.01729696 0.146204001 5.50E-05 4.259886778 0.82888224 SAEIDS(ph)DDTGGSAAQK ddPTM_HeLa_Curcumin_4h_R1 1 SAEIDSDDTGGSAAQK 16 0 P33176 P33176 KIF5B Kinesin-1 heavy chain 1 0 SAEIDS(0.999)DDT(0.001)GGSAAQK 224.67 1.98E-16 6143400 2038.3 1640.3 1794.2 1743.4 1664.7 1798 1391.7 1028 2021.5 1822.3 TRUE FALSE FALSE 1876.966404 1782.080223 1860.69463 1736.186273 1644.84954 1425.074532 1430.747356 1341.432468 1799.746508 1885.624789 0.995408214 0.945087397 0.986778834 0.920748541 0.872310095 0.755757211 0.75876567 0.711399466 0.954456325 1 10.88082691 -5.488549125 0.913860269 0.996134049 0.707308101 0.952681267 0.022623649 0.068679102 0.100140219 0.00289005 0.012883921 3.25E-06 5.488549125 -0.288825948 SAEKEISLWFKPEELVDYK ddPTM_HeLa_Curcumin_4h_R1 2 SAEKEISLWFKPEELVDYK 19 2 Q32Q12;P22392-2;P22392 Q32Q12 NME1-NME2;NME2 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B 0 0 ; ; 77.027 0.0022282 64161000 6631.5 4543.7 4197.1 4798.8 3082.2 6858.2 4815.7 4713.7 6583.4 6039.6 FALSE FALSE TRUE 6106.609777 4936.437182 4352.648218 4778.943837 3045.446778 5435.732012 4950.815581 6150.885431 5861.217491 6249.47565 0.977139542 0.789896218 0.696482147 0.764695169 0.487312368 0.869790094 0.792196955 0.984224241 0.937873482 1 12.60951943 -7.239629698 3.897290566 0.990335597 0.757932716 0.370252962 0.120381382 0.150998624 5.142828566 0.020106417 0.024076973 5.76E-08 7.239629698 -0.232402881 SAENPPSGS(ph)VRK ddPTM_HeLa_Curcumin_4h_R1 2 SAENPPSGSVRK 12 1 Q5JXX1;Q5JXX2;Q15014 Q5JXX1 MORF4L2 Mortality factor 4-like protein 2 1 0 SAENPPS(0.151)GS(0.849)VRK;SAENPPS(0.245)GS(0.755)VRK ; 79.326 0.011865 73406000 5028.3 4202.5 3878.3 4545.3 4290.7 6109.2 5715.9 3553.6 4770.9 4588.9 TRUE FALSE FALSE 4630.304749 4565.745374 4022.03321 4526.492753 4239.536205 4842.083055 5876.27277 4637.076281 4247.544206 4748.363933 0.975136871 0.961540741 0.847035582 0.953274184 0.892841464 1.01973714 1.237536308 0.976562948 0.89452794 1 12.2132148 -4.990276592 24.77531791 0.966499417 1.112446457 0.40683291 0.077707905 134.9896659 343948.1318 0.009910637 0.029679768 1.02E-05 4.990276592 0.14594704 TTSFFLNS(ph)PEKEHQEMDEGSQSLEK ddPTM_HeLa_Curcumin_4h_R1 1 TTSFFLNSPEKEHQEMDEGSQSLEK 25 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 0 T(0.003)T(0.003)S(0.008)FFLNS(0.98)PEKEHQEMDEGS(0.005)QS(0.002)LEK 55.051 0.018871 9140100 1061.4 968.88 1139.7 1381.9 1200.6 1443.4 952.22 331.21 1488.3 1251.7 TRUE FALSE FALSE 977.38907 1052.62567 1181.938285 1376.182064 1186.283629 1144.02257 978.9367304 432.1944043 1325.037214 1295.196482 0.7546261 0.812715047 0.9125552 1.062527642 0.915910169 0.883281097 0.755821023 0.333690224 1.02303954 1 10.33895526 -4.242821703 2.138399088 0.894055854 0.164159868 0.787780061 0.091289763 0.298910313 1.448845053 0.015466643 0.423805223 5.72E-05 4.242821703 -0.729895986 down ENPVVVGEK(ac)IQK ddPTM_HeLa_Curcumin_4h_R1 2 ENPVVVGEKIQK 12 1 Q6FIF0-2;Q6FIF0 Q6FIF0-2 ZFAND6 AN1-type zinc finger protein 6 0 1 ; ENPVVVGEK(1)IQK;ENPVVVGEK(1)IQK 176.29 1.49E-07 2537100 2489.74 2749.49 2699.28 2721.5 2840.88 3851.6 2641.97 4784.1 2374.68 2041.02 FALSE TRUE FALSE 2292.674452 2987.143664 2799.317691 2710.239154 2807.004361 3052.734744 2716.096568 6242.750067 2114.183545 2111.945293 1.085574735 1.414403902 1.325468846 1.283290416 1.329108463 1.445461089 1.286063885 2.955924136 1.001059806 1 11.04435675 -2.188488439 1.124955049 1.129368837 199.9999993 0.884794018 0.182049975 42.63896923 0.620951016 0.030409291 21280.97027 0.006479053 2.188488439 198.8706305 up SAEPRPELGPGQETGTNS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 SAEPRPELGPGQETGTNSR 19 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;Q9Y4B5-4 Q9Y4B5;Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 1 0 SAEPRPELGPGQET(0.001)GT(0.003)NS(0.996)R;SAEPRPELGPGQET(0.001)GT(0.012)NS(0.986)R ; 122.35 8.83E-05 50525000 2604.6 2562 2818.7 2653 3093.6 2662.8 2312 1173.33 2922.3 2361.5 TRUE FALSE FALSE 2398.443162 2783.447864 2923.163502 2642.022589 3056.71084 2110.505264 2376.868498 1531.072916 2601.731001 2443.561949 0.981535648 1.139094454 1.196271493 1.081217765 1.250924226 0.863700331 0.972706462 0.626574217 1.06472889 1 11.25476996 -3.912643016 1.372126096 1.036171664 0.092670188 0.597204798 0.107631738 1.793253276 1.569914747 0.016857536 2.948637804 0.00012228 3.912643016 -0.943501477 SAEPSANTTLVS(ph)ETEEEGSVPAFGAAAK ddPTM_HeLa_Curcumin_4h_R1 2 SAEPSANTTLVSETEEEGSVPAFGAAAK 28 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 SAEPSANTTLVS(0.993)ET(0.006)EEEGSVPAFGAAAK;S(0.002)AEPS(0.006)ANT(0.07)T(0.059)LVS(0.786)ET(0.059)EEEGS(0.018)VPAFGAAAK ; 127.68 1.44E-10 22035000 5544.24 5366.5 5709.59 5346.79 6857 5422.7 5640.1 5216.4 4654.53 3867.22 TRUE FALSE FALSE 5105.407554 5830.356347 5921.192428 5324.6664 6775.234753 4297.970894 5798.346026 6806.856347 4143.939704 4001.605607 1.275839764 1.457004243 1.479704151 1.330632482 1.693129063 1.074061593 1.449004873 1.70103129 1.035569247 1 11.96636327 -8.214493405 0.528124738 0.993984076 1.465488949 0.506025353 0.169617061 0.499510883 0.313823643 0.101973243 0.051764749 6.10E-09 8.214493405 0.471504874 SAEPSPTVMSTS(ph)LGSNLSELDR ddPTM_HeLa_Curcumin_4h_R1 3 SAEPSPTVMSTSLGSNLSELDR 22 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-3;A0A1B0GU60;F5H836 A0A1B0GTU4 PXN Paxillin 1 0 SAEPSPTVMST(0.074)S(0.924)LGS(0.002)NLSELDR;SAEPS(0.001)PT(0.008)VMS(0.01)T(0.174)S(0.75)LGS(0.053)NLS(0.004)ELDR;SAEPSPTVMS(0.002)T(0.006)S(0.99)LGS(0.002)NLS(0.001)ELDR ;; 180.41 3.63E-24 21892500 28814.3 26614.7 28973.3 27820.2 30387.1 35032.9 27212.4 29155.6 32378.8 28375.1 TRUE FALSE FALSE 26533.61775 28915.15608 30047.07599 27705.08738 30024.75368 27766.68164 27975.90671 38045.00822 28826.92665 29361.13261 0.903698713 0.984810649 1.023362293 0.943597366 1.022602025 0.945695182 0.952821101 1.295760921 0.981805676 1 14.84162 -4.260330298 24.9895906 0.963421834 1.295761027 0.872074863 0.036898557 26.85284573 604963.8615 0.00609934 0.04998412 5.49E-05 4.260330298 0.332339193 SAEQEK(ac)DPISLK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 SAEQEKDPISLKR 13 2 Q9Y3Y4-2 Q9Y3Y4-2 PYGO1 Pygopus homolog 1 0 2 SAEQEK(1)DPISLK(1)R 122.7 0.004933 2955100 3425.2 3022.6 3562.1 3341.9 2904.2 3851.2 1809.5 3268.5 2892.3 2442.9 FALSE TRUE FALSE 3154.091806 3283.860076 3694.11456 3328.072103 2869.569312 3052.417708 1860.2697 4265.050604 2575.021926 2527.790593 1.247766257 1.299102894 1.461400549 1.316593278 1.135208478 1.20754374 0.735927139 1.687264212 1.018684828 1 11.30366124 -9.026175666 0.894233949 1.004902343 1.245633887 0.158007665 0.228986778 0.863657387 1.289957171 0.128271218 0.042398272 9.42E-10 9.026175666 0.240731543 SAEQQPSEK(ac)STEPK ddPTM_HeLa_Curcumin_4h_R1 1 SAEQQPSEKSTEPK 14 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E7EVY3;E9PCH5;F8W7E0;E9PSG1;H0YA91;H0Y944;D6RBR1;D6RGF7;E7EQK6 P20810-6 CAST Calpastatin 0 1 SAEQQPSEK(1)STEPK 225.79 1.83E-28 669080 192.93 146.82 208.23 267.99 62.519 157.86 134.77 232.95 188.55 191.96 FALSE TRUE FALSE 177.6593869 159.5104666 215.947187 266.8811284 61.77350176 125.1180566 138.5512835 303.9753826 167.8665367 198.6305957 0.894421055 0.803050839 1.087179879 1.343605336 0.310996911 0.629903244 0.697532437 1.530355289 0.845119233 1 7.633944053 -5.778823313 24.99998785 0.972735708 0.773842496 0.085355386 0.31869689 473.4608845 680887.6222 0.04520626 0.082080472 1.66E-06 5.778823313 -0.198893212 SAES(ph)PSWTPAEHVAK ddPTM_HeLa_Curcumin_4h_R1 2 SAESPSWTPAEHVAK 15 0 Q13415 Q13415 ORC1 Origin recognition complex subunit 1 1 0 SAES(0.928)PS(0.072)WTPAEHVAK;S(0.029)AES(0.624)PS(0.347)WTPAEHVAK ; 212.39 1.21E-10 37014000 7662.9 6283.4 7344.8 7905.2 7906.4 9448.2 6073.5 2885.3 8131.5 6564.4 TRUE FALSE FALSE 7056.373379 6826.509098 7617.004749 7872.490377 7812.121344 7488.536817 6243.906064 3765.014688 7239.494794 6792.512411 1.038845857 1.005005024 1.121382529 1.158995361 1.150107776 1.102469361 0.919233663 0.554288967 1.065805162 1 12.72972958 -4.308664192 2.77020416 1.048745598 0.489020108 0.871440782 0.060290287 0.118752616 1.309954617 0.0101652 0.142499681 4.91E-05 4.308664192 -0.559725489 QPEYS(ph)PES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 QPEYSPESPR 10 0 Q9H6F5 Q9H6F5 CCDC86 Coiled-coil domain-containing protein 86 2 0 QPEYS(1)PES(1)PR 122.52 0.0098579 10036000 2846.6 2562.7 2549.2 2581.5 3044 3324.9 3187 4011.4 2580.4 2416.9 TRUE FALSE FALSE 2621.288606 2784.208369 2643.675595 2570.818437 3007.702288 2635.278261 3276.418643 5234.457394 2297.336576 2500.887095 1.048143521 1.11328831 1.05709514 1.027962615 1.202654168 1.053737398 1.310102583 2.093040267 0.918608673 1 11.28822421 -4.122042419 1.677199025 1.04344503 2.758726668 0.952232696 0.070066184 0.178427314 0.364626971 0.008807875 0.546941412 7.55E-05 4.122042419 1.715281638 up SAES(ph)PTSPVTSETGSTFK ddPTM_HeLa_Curcumin_4h_R1 3 SAESPTSPVTSETGSTFK 18 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 S(0.005)AES(0.765)PT(0.218)S(0.013)PVTSETGSTFK;S(0.001)AES(0.793)PT(0.205)S(0.002)PVTSETGSTFK;S(0.007)AES(0.761)PT(0.225)S(0.004)PVT(0.001)S(0.001)ETGSTFK ;; 134.82 0.0002713 45460700 6119.4 5363.4 6382.1 6122.5 7742.1 7444.7 5889.5 4608.4 6246.4 5619 TRUE FALSE FALSE 5635.043033 5826.988397 6618.62624 6097.166717 7649.780514 5900.585301 6054.743519 6013.479946 5561.185548 5814.259832 0.969176335 1.002189198 1.138343733 1.04865742 1.315692923 1.014847198 1.041361015 1.034264054 0.956473517 1 12.50537983 -6.851872733 6.098768166 0.985589327 1.099792574 0.329201783 0.081893482 0.190631285 10.53100135 0.012871343 0.017014143 1.41E-07 6.851872733 0.114203247 SAESPT(ph)SPVTSETGSTFK ddPTM_HeLa_Curcumin_4h_R1 1 SAESPTSPVTSETGSTFK 18 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 S(0.005)AES(0.353)PT(0.621)S(0.021)PVTSETGSTFK 130.29 0.00066056 14219000 2286.1 2367.6 3041.6 2656.8 2497.6 3122.4 2261.6 1909.9 2539.1 1990.5 TRUE FALSE FALSE 2105.152773 2572.244794 3154.324372 2645.806866 2467.817751 2474.779043 2325.054409 2492.219718 2260.567083 2059.669727 1.022082689 1.248862748 1.531470959 1.284578217 1.19816188 1.201541689 1.128848174 1.210009394 1.097538626 1 11.0081973 -7.262725109 5.906072101 1.009971647 1.260336951 0.470922525 0.104434744 0.090559391 13.64069738 0.018357169 0.021689331 5.46E-08 7.262725109 0.250365304 SAESPTS(ph)PVTSETGSTFKK ddPTM_HeLa_Curcumin_4h_R1 1 SAESPTSPVTSETGSTFKK 19 1 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 S(0.005)AES(0.263)PT(0.326)S(0.405)PVTSETGSTFKK 137.09 9.48E-05 56514000 2833.4 2097.6 3003.7 2451.5 2378.9 3236.2 2037.9 2044 3039.1 2286.3 TRUE FALSE FALSE 2609.1334 2278.907197 3115.019764 2441.356343 2350.533171 2564.975641 2095.077989 2667.206191 2705.718333 2365.748755 1.102878484 0.963292147 1.316716223 1.031959263 0.993568386 1.084213036 0.885587696 1.127425803 1.143704854 1 11.20808115 -3.928167055 21.12354513 1.04968686 3.686108475 0.029002775 0.11157526 1898.063663 531544.3505 0.013855309 11261.81691 0.000117987 3.928167055 2.636421615 TVPST(ph)PTLVVPHR ddPTM_HeLa_Curcumin_4h_R1 2 TVPSTPTLVVPHR 13 0 P12270 P12270 TPR Nucleoprotein TPR 1 0 TVPS(0.032)T(0.968)PTLVVPHR;TVPS(0.254)T(0.745)PTLVVPHR ; 168.93 0.00018131 81927000 4474.7 4345.8 5467.8 4941.7 6726.2 8159.5 18015.8 39882 0 3123 TRUE FALSE FALSE 4120.522773 4721.431587 5670.441478 4921.252555 6645.994458 6467.127723 18521.27486 52041.83821 0 3231.524018 1.275102011 1.461054153 1.754726701 1.522889054 2.056613048 2.001262466 5.731436548 16.10442563 0 1 11.657999 -4.120812677 1.517886037 1.275957271 25.94364642 0.986815944 0.516449464 0.085754846 0.139002761 0.054797706 3.478762484 7.57E-05 4.120812677 24.66768915 up EENTSNESTDVTKGDSK(ac)NAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 EENTSNESTDVTKGDSKNAKK 21 3 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 0 2 ; EENTSNESTDVTKGDSK(1)NAK(1)K;EENTSNESTDVTK(0.004)GDSK(0.996)NAK(1)K 191.89 7.25E-14 22861300 7016.3 5424.8 6468.7 6951.3 7152.9 7762.6 5335 2210.76 7044.2 5677.8 FALSE TRUE FALSE 6460.952451 5893.69554 6708.435712 6922.537362 7067.606339 6152.549257 5484.685742 2884.810547 6271.468884 5875.103127 1.099717283 1.00316461 1.141841354 1.178283549 1.202975707 1.047224044 0.933547143 0.491022963 1.067465327 1 12.52039846 -4.24910274 2.20823484 1.072199603 0.327995692 0.880030648 0.066677147 0.194983945 1.043391299 0.011193353 0.286574537 5.64E-05 4.24910274 -0.744203911 down SAGALEEGTSEGQLCGRS(ph)AR ddPTM_HeLa_Curcumin_4h_R1 1 SAGALEEGTSEGQLCGRSAR 20 1 H7BXQ8;C9J5N7;Q8N2F6-3;Q8N2F6 H7BXQ8 ARMC10 Armadillo repeat-containing protein 10 1 0 SAGALEEGTSEGQLCGRS(1)AR 64.454 0.0046231 23330000 2041 1377.2 1672.8 1611.8 1496.7 1929.9 1537.3 1772.7 1941.9 1713 TRUE FALSE FALSE 1879.452696 1496.239031 1734.79544 1605.130799 1478.85283 1529.616986 1580.432501 2313.188069 1728.878428 1772.526622 1.0603241 0.844127819 0.978713334 0.905560897 0.834319108 0.86295854 0.891626947 1.305023033 0.975375155 1 10.79159158 -7.289130756 24.42530556 1.028486383 0.936160282 0.042865522 0.130244407 939.3789361 828580.9288 0.021207416 0.024254661 5.14E-08 7.289130756 -0.092326101 SAGAPASVSGQDADGST(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 SAGAPASVSGQDADGSTSPR 20 0 K7EQY5;P42679-3;P42679;P42679-2 K7EQY5 MATK Non-specific protein-tyrosine kinase;Megakaryocyte-associated tyrosine-protein kinase 1 0 SAGAPASVSGQDADGS(0.009)T(0.495)S(0.495)PR 125.04 0.0017632 0 1115.6 983.04 922.26 1340 1154.5 1080.5 880.54 795.24 1049.2 1213.2 TRUE FALSE FALSE 1027.299083 1068.009597 956.4397669 1334.455435 1140.733342 856.3921203 905.2455825 1037.705015 934.105385 1255.35861 0.818331172 0.850760563 0.761885695 1.063007355 0.908691216 0.682189228 0.721105169 0.826620383 0.744094459 1 10.29388383 -13.52287875 0.178157193 1.728871891 0.782348631 0 0.126538095 54.68867404 0.623953259 13.89294676 0.148668404 3.00E-14 13.52287875 -0.94652326 SAGEALGSSGT(ph)PPVR ddPTM_HeLa_Curcumin_4h_R1 2 SAGEALGSSGTPPVR 15 0 E7ER32;A0A087X287;A0A087WU73;A0A494BZX7;W0Z7M9;B0QY83;A0A499FIJ6;Q969V6 E7ER32 MKL1;mkl1 MKL/myocardin-like protein 1 1 0 SAGEALGSS(0.001)GT(0.999)PPVR;SAGEALGS(0.002)S(0.016)GT(0.982)PPVR ; 194.67 4.56E-06 44021000 2400.77 1801.82 1747.67 2334.8 2250.52 4543.3 4114.7 2589 2408.63 1865.52 TRUE FALSE FALSE 2210.746521 1957.561292 1812.440188 2325.139216 2223.684019 3600.968366 4230.147408 3378.374182 2144.409315 1930.346681 1.145258799 1.014098302 0.938919524 1.20451898 1.151960962 1.865451632 2.191392587 1.750138571 1.110893362 1 10.91464426 -5.254371762 3.399466194 1.066426816 1.987322954 0.911905426 0.122229583 0.04461987 1.091052787 0.01689787 0.044413196 5.57E-06 5.254371762 0.920896138 SAGGRPGS(ph)GPQLGTGR ddPTM_HeLa_Curcumin_4h_R1 2 SAGGRPGSGPQLGTGR 16 1 K7EM11;K7ESN1;O14908-2;O14908 K7EM11 GIPC1 PDZ domain-containing protein GIPC1 1 0 S(0.003)AGGRPGS(0.997)GPQLGTGR;SAGGRPGS(0.981)GPQLGT(0.019)GR ; 142.4 0.0036806 24025000 3457.12 3243.15 3209.33 3459.87 3728.2 4226.4 3100.95 1389.94 3622.51 3214.17 TRUE FALSE FALSE 3183.485304 3523.473435 3328.270593 3445.553975 3683.74365 3349.796999 3187.954311 1813.726308 3225.129716 3325.862168 0.957190991 1.059416553 1.000724151 1.035988204 1.107605626 1.007196579 0.958534705 0.54534019 0.969712379 1 11.69951267 -4.259137694 3.822516343 1.000858618 0.49868791 0.911575614 0.043582047 0.060544484 1.710286604 0.00682835 0.085309904 5.51E-05 4.259137694 -0.502170708 SAGGSS(ph)PEGGEDS(ph)DREDGNYCPPVK ddPTM_HeLa_Curcumin_4h_R1 2 SAGGSSPEGGEDSDREDGNYCPPVK 25 1 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4;K7EID7;K7ENB9 B7Z7F3 RANBP3 Ran-binding protein 3 2 0 S(0.009)AGGS(0.536)S(0.581)PEGGEDS(0.873)DREDGNY(0.002)CPPVK;S(0.006)AGGS(0.209)S(0.823)PEGGEDS(0.939)DREDGNY(0.023)CPPVK ; 61.538 0.002907 16835100 4005.5 4085.3 3644.8 4212.6 4330.1 4975 3914.6 4715.7 3966.4 3387.4 TRUE FALSE FALSE 3688.460448 4438.415128 3779.879494 4195.169377 4278.466386 3943.12892 4024.43314 6153.495222 3531.295843 3505.111898 1.052308901 1.266269168 1.078390535 1.19687174 1.220636177 1.124965204 1.148161102 1.755577397 1.007470217 1 11.77524479 -1.767016488 1.10427277 1.070537049 200 0.788990611 0.095613677 158.1773245 0.846202404 0.016121403 78916.63148 0.017099504 1.767016488 198.929463 SAGGSS(ph)PEGGEDS(ph)DREDGNYCPPVKR ddPTM_HeLa_Curcumin_4h_R1 1 SAGGSSPEGGEDSDREDGNYCPPVKR 26 2 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4;K7EID7;K7ENB9 B7Z7F3 RANBP3 Ran-binding protein 3 2 0 S(0.006)AGGS(0.274)S(0.75)PEGGEDS(0.957)DREDGNY(0.013)CPPVKR 50.873 0.013079 66844000 3835.8 3437.6 3549.1 3787.5 3396.1 4642.3 3522.5 4371.7 4488.6 3672.3 TRUE FALSE FALSE 3532.192382 3734.730826 3680.632768 3771.828329 3355.603726 3679.43465 3621.33187 5704.611205 3996.21181 3799.912152 0.9295458 0.982846623 0.968609963 0.992609349 0.883074027 0.968294661 0.953004103 1.501248181 1.051658999 1 11.89175035 -4.260802107 24.99650171 0.962876249 1.501248346 0.933096445 0.042640864 7.536538959 295548.0342 0.004925621 0.039275493 5.49E-05 4.260802107 0.538372098 SAGGSSPEGGEDS(ph)DREDGNYCPPVKR ddPTM_HeLa_Curcumin_4h_R1 2 SAGGSSPEGGEDSDREDGNYCPPVKR 26 2 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4;K7EID7;K7ENB9 B7Z7F3 RANBP3 Ran-binding protein 3 1 0 SAGGS(0.002)S(0.003)PEGGEDS(0.995)DREDGNY(0.001)CPPVKR;SAGGSSPEGGEDS(0.995)DREDGNY(0.004)CPPVKR ; 73.383 0.00029091 203768000 2170.22 2304.22 2253.8 2227.67 2000.77 2364.92 1790.83 1747.25 2671.73 1849.18 TRUE FALSE FALSE 1998.444797 2503.386509 2337.327811 2218.452492 1976.912124 1874.408934 1841.07587 2279.978482 2378.647903 1913.438867 1.044425736 1.308317999 1.221532525 1.159405994 1.033172347 0.979602205 0.962181704 1.191560661 1.243127201 1 10.90195209 -7.500075667 20.41903278 1.019598853 1.116998468 0 0.124543274 39.9344277 35762.16272 0.019651879 0.021176964 3.16E-08 7.500075667 0.097399615 SAGQGEVLVYVEDPAGHQEEAK ddPTM_HeLa_Curcumin_4h_R1 2 SAGQGEVLVYVEDPAGHQEEAK 22 0 P21333-2;P21333;F8WE98;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 195.15 2.56E-13 18367100 5854.5 4109.9 5798.9 5664.3 6574.6 6449.6 5470.7 5192.6 5466.1 4318.3 FALSE FALSE TRUE 5391.110147 4465.141443 6013.812335 5640.862627 6496.202189 5111.880258 5624.193118 6775.799836 4866.482506 4468.360604 1.206507403 0.999279566 1.34586549 1.26240094 1.453822277 1.144016947 1.258670375 1.516395036 1.08909798 1 12.1255299 -4.13954837 0.036160212 5.60E-09 2.735061623 0.475735933 0.121436916 245.6975984 1.359263379 39.07554981 66.68830018 7.25E-05 4.13954837 2.735061618 SAGSMCITQFMK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 SAGSMCITQFMKK 13 1 Q13111 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 0 1 ; SAGSMCITQFMK(1)K;SAGSMCITQFMK(1)K 95.401 0.002738 81999000 18894.5 19440 13221.2 13263.5 21339.6 39778 16872.2 13879.7 21571.5 14341.7 FALSE TRUE FALSE 17398.98039 21120.30698 13711.1893 13208.61915 21085.13921 31527.59441 17345.58852 18111.55664 19205.16042 14840.07301 1.172432264 1.423194277 0.923930044 0.890064297 1.420824493 2.124490519 1.168834447 1.220449295 1.29414191 1 13.85721057 -5.618198581 6.739606003 1.087559873 1.519244696 0.282274311 0.285515597 0.184882267 11.11863141 0.04026103 0.080960819 2.41E-06 5.618198581 0.431684824 SAINEVVTR ddPTM_HeLa_Curcumin_4h_R1 1 SAINEVVTR 9 0 H7C2W9;C9JU56;B7Z4E3;B7Z4C8;P62899-3;P62899;P62899-2;B8ZZK4 H7C2W9 RPL31 60S ribosomal protein L31 0 0 112.11 0.0029338 8867100 2301.2 2027 2131.6 2235.9 2099.4 3043.5 2077.7 1892.9 2312.3 1986.8 FALSE FALSE TRUE 2119.057592 2202.204848 2210.598971 2226.648438 2074.366026 2412.243793 2135.99467 2470.036496 2058.646475 2055.841152 1.030749671 1.071194068 1.075277129 1.083083893 1.009010849 1.173360982 1.038988186 1.201472445 1.001364562 1 11.00551308 -1 0.168354124 0.987400639 1.642892177 0.500159355 0.046884829 33.80379926 0.352978007 0.064697822 5.595933646 0.1 1 0.655491537 SAKPSEK(ac)PR ddPTM_HeLa_Curcumin_4h_R1 2 SAKPSEKPR 9 2 J3KPH8;Q8WUI4-3;Q8WUI4-4;Q8WUI4;Q8WUI4-7;Q8WUI4-6;Q8WUI4-5;Q8WUI4-8;Q8WUI4-10 J3KPH8 HDAC7 Histone deacetylase;Histone deacetylase 7 0 1 ; SAK(0.001)PSEK(0.999)PR;SAKPSEK(1)PR 74.165 0.014628 7425000 4631.1 3780.2 4418.6 3296.1 4299.9 5610 5516.5 3524.1 4365.3 3779.8 FALSE TRUE FALSE 4264.543548 4106.943644 4582.357203 3282.461612 4248.626501 4446.422762 5671.278143 4598.581867 3886.437511 3911.147769 1.090356029 1.050060976 1.17161444 0.839257887 1.086286367 1.136858801 1.450029116 1.175762753 0.993682096 1 11.93337633 -4.963314619 4.942390517 1.042887524 1.313512379 0.53824722 0.102337475 0.098843413 5.839016252 0.013240435 0.040696492 1.09E-05 4.963314619 0.270624855 SAKPTK(ac)PAASDLPVPAEGVR ddPTM_HeLa_Curcumin_4h_R1 1 SAKPTKPAASDLPVPAEGVR 20 2 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1;C9J813 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 0 1 SAK(0.046)PTK(0.954)PAASDLPVPAEGVR 108.71 1.44E-06 0 692.32 666.62 569 622.72 1314.4 1279.7 921.81 975.17 1479.2 525.12 FALSE TRUE FALSE 637.5221415 724.2396624 590.0876405 620.1433496 1298.726638 1014.275795 947.6735077 1272.494844 1316.935461 543.3678809 1.173279032 1.332871684 1.085981821 1.141295559 2.390142451 1.866646577 1.744073474 2.341866144 2.42365349 1 9.085785479 -5.776364639 24.82644631 1.108714946 2.045636069 0.293132325 0.461117086 58.47507497 97266.516 0.029067852 0.052847086 1.67E-06 5.776364639 0.936921123 SAKPTKPAASDLPVPAEGVR ddPTM_HeLa_Curcumin_4h_R1 2 SAKPTKPAASDLPVPAEGVR 20 2 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1;C9J813 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 0 0 ; ; 63.184 0.0066797 21188200 9164.4 7028.3 7653.3 8040.6 8114.8 9567.6 7480.2 7945.5 9093.2 8530.1 FALSE FALSE TRUE 8439.02807 7635.794935 7936.938031 8007.330128 8018.03631 7583.171911 7690.07428 10368.04637 8095.69871 8826.52034 0.956099091 0.865096849 0.899214835 0.907189903 0.908402859 0.859134927 0.871246424 1.174647083 0.917201615 1 13.10762908 -7.837239874 1.668890431 0.98686609 0.919739781 0 0.089703471 0.544307793 3.151890127 0.017773803 0.016683231 1.45E-08 7.837239874 -0.067126309 SALAPNLLTS(ph)GK ddPTM_HeLa_Curcumin_4h_R1 2 SALAPNLLTSGK 12 0 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 0 SALAPNLLT(0.06)S(0.94)GK;SALAPNLLT(0.079)S(0.921)GK ; 159.58 0.0002332 97341000 7527 5906.9 6260.2 6207.8 7104.5 11603.3 11000 4210.6 7179.7 5076.7 TRUE FALSE FALSE 6931.230008 6417.466115 6492.208519 6182.113768 7019.783478 9196.644784 11308.6304 5494.392557 6392.104873 5253.114947 1.319451426 1.221649665 1.235877871 1.176847229 1.336308752 1.750703131 2.152747562 1.045930388 1.216821817 1 12.35895744 -5.425987674 3.414152541 1.170430637 1.697688668 0.364716867 0.264118529 0.171202828 3.734012643 0.037272935 0.088035844 3.75E-06 5.425987674 0.527258031 SALAPNLLTS(ph)GKK ddPTM_HeLa_Curcumin_4h_R1 2 SALAPNLLTSGKK 13 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 0 SALAPNLLT(0.039)S(0.961)GKK;SALAPNLLT(0.068)S(0.932)GKK ; 128.35 0.0027761 34275000 3413.5 2742.4 3307.6 3506 3237.3 6041.1 5420.4 2120.45 3674.2 2528.5 TRUE FALSE FALSE 3143.317873 2979.440836 3430.182566 3491.493101 3198.697312 4788.107763 5572.481836 2766.965444 3271.149452 2616.365187 1.201406397 1.138771014 1.311048849 1.334482326 1.222572953 1.830060951 2.129856285 1.05756087 1.250264859 1 11.35334821 -5.797194836 1.009643986 1.102298622 1.696513691 0.314433095 0.279713245 0.379597992 0.746578352 0.044665891 0.134624604 1.60E-06 5.797194836 0.594215069 SALAPNLLTSGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 SALAPNLLTSGKK 13 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 0 1 ; SALAPNLLTSGK(1)K;SALAPNLLTSGK(1)K 187.58 7.86E-10 10183400 7057.8 5728.3 6930.9 6148.6 5468.5 8105.4 6072.4 6097.1 7034.6 6283.8 FALSE TRUE FALSE 6499.167683 6223.428727 7187.765251 6123.158722 5403.291709 6424.248673 6242.775201 7956.077722 6262.92198 6502.161582 0.999539553 0.957132278 1.105442423 0.941711252 0.830999298 0.988017383 0.960107669 1.223605046 0.963206143 1 12.66670369 -4.257519129 24.33154948 0.986087423 1.223605182 0.564071479 0.06533172 157.2073323 975667.7082 0.008921159 0.089763017 5.53E-05 4.257519129 0.237517759 SALLTQNGTGS(ph)LPR ddPTM_HeLa_Curcumin_4h_R1 2 SALLTQNGTGSLPR 14 0 Q86UU1-3;Q86UU1-2;Q86UU1;A0A087WZL0 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 0 SALLTQNGT(0.008)GS(0.992)LPR;SALLT(0.002)QNGT(0.179)GS(0.819)LPR ; 181.97 0.0001032 54100000 2434.41 2422.24 2214.98 2267.06 2242.63 3158.9 3385.1 1411.59 2888.5 2468.69 TRUE FALSE FALSE 2241.72388 2631.607632 2297.069107 2257.679506 2215.888102 2503.708532 3480.076795 1841.977293 2571.638777 2554.476794 0.877566743 1.030194378 0.899232717 0.883812886 0.867452821 0.980125769 1.362344259 0.721078108 1.006718395 1 11.31881211 -4.987185961 24.98464684 0.93516847 1.074092077 0.059174908 0.154237728 332.6704403 648626.9844 0.018930193 0.056744007 1.03E-05 4.987185961 0.138923608 SALNLNQPVSVSS(ph)VSPVKATQK ddPTM_HeLa_Curcumin_4h_R1 2 SALNLNQPVSVSSVSPVKATQK 22 1 Q86XJ1;G3V1N3;H0YIT6 Q86XJ1 GAS2L3 GAS2-like protein 3 1 0 SALNLNQPVS(0.089)VS(0.144)S(0.442)VS(0.31)PVKAT(0.015)QK;SALNLNQPVS(0.011)VS(0.055)S(0.781)VS(0.153)PVKATQK ; 89.055 0.00017334 40934000 4475.3 2938.5 3378.29 4566.3 3321.22 6244.1 4616.6 2456.29 6723.9 4652.68 TRUE FALSE FALSE 4121.075283 3192.490846 3503.492399 4547.405861 3281.616621 4949.003274 4746.129371 3205.201514 5986.304992 4814.360284 0.855996444 0.663118391 0.72771712 0.944550385 0.681630877 1.027966954 0.985827626 0.665758548 1.243426881 1 12.23312839 -8.642328006 0.990771552 0.98515566 0.82612803 0.314425259 0.152627814 0.575466018 1.140111878 0.049466525 0.025505932 2.28E-09 8.642328006 -0.15902763 NVT(ph)PNSYAEPLAAPGGGER ddPTM_HeLa_Curcumin_4h_R1 2 NVTPNSYAEPLAAPGGGER 19 0 Q9NYD6 Q9NYD6 HOXC10 Homeobox protein Hox-C10 1 0 NVT(0.994)PNS(0.006)YAEPLAAPGGGER;NVT(0.999)PNS(0.001)YAEPLAAPGGGER ; 191.89 1.75E-09 18951700 3333 2744.8 3445.4 3185.5 3032 3866.6 2489.8 506.282 3806.4 2885.2 TRUE FALSE FALSE 3069.189533 2982.048281 3573.089555 3172.319245 2995.84538 3064.623574 2559.657087 660.6450512 3388.847443 2985.460485 1.028045606 0.998857059 1.196830296 1.062589594 1.00347849 1.026516207 0.857374298 0.221287488 1.135117165 1 11.54373776 -4.241323262 2.320328335 1.029422921 2.00E-13 0.935288847 0.065701678 0.100354818 0.604328955 0.008364762 0.212548296 5.74E-05 4.241323262 -1.029422921 down SALVTSSSS(ph)LPSFPSTLSWSR ddPTM_HeLa_Curcumin_4h_R1 2 SALVTSSSSLPSFPSTLSWSR 21 0 F8VXI9;Q14161-6;Q14161-4;Q14161-3;Q14161 F8VXI9 GIT2 ARF GTPase-activating protein GIT2 1 0 SALVTS(0.002)S(0.007)S(0.008)S(0.983)LPSFPSTLSWSR;SALVTSSS(0.007)S(0.992)LPSFPSTLSWSR ; 152.59 1.40E-10 5842500 1055.28 1028.66 951.34 953.25 674.04 1966.24 1102.93 613.31 1223.05 1097.45 TRUE FALSE FALSE 971.7534745 1117.572787 986.5974973 949.3057041 666.0025132 1558.41966 1133.875247 800.3053957 1088.884475 1135.586306 0.855728419 0.984137252 0.868800101 0.835960859 0.586483396 1.372348057 0.998493238 0.704750834 0.958874257 1 10.14922164 -9.527729967 1.260855301 1.000457003 0.902587772 0.023696659 0.196144987 1.618938497 4.573640413 0.137061105 0.032159606 2.97E-10 9.527729967 -0.097869231 SAMDSPVPASMFAPEPSS(ph)PGAAR ddPTM_HeLa_Curcumin_4h_R1 1 SAMDSPVPASMFAPEPSSPGAAR 23 0 O00178;F8WAZ4 O00178 GTPBP1 GTP-binding protein 1 1 0 SAMDSPVPAS(0.003)MFAPEPS(0.029)S(0.968)PGAAR 83.411 0.00018566 19313000 2063.1 1973.9 1831.7 2112.4 2122.2 2977.3 1832.1 1609.7 2654.4 1937 TRUE FALSE FALSE 1899.803458 2144.51512 1899.584413 2103.659449 2096.894151 2359.774419 1883.503795 2100.49012 2363.218961 2004.310606 0.947858806 1.069951491 0.947749519 1.049567588 1.046192214 1.177349664 0.939726502 1.047986332 1.179068231 1 10.96889038 -6.234864356 18.66739109 0.98146625 1.052541214 0 0.08823841 36.4747482 25620.03086 0.009145509 0.015152858 5.82E-07 6.234864356 0.071074963 SAMEEPSS(ph)SEAPAK ddPTM_HeLa_Curcumin_4h_R1 1 SAMEEPSSSEAPAK 14 0 A1L390-3;A1L390;A0A0U1RR71;G3V3I3;G3V278 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 0 S(0.001)AMEEPS(0.279)S(0.36)S(0.36)EAPAK 86.944 0.014883 5194200 158.65 153.1 135.01 172.72 140.25 75.605 113.56 0 128.69 158.87 TRUE FALSE FALSE 146.0926851 166.3332818 140.0135894 172.0053304 138.5776104 59.92367076 116.746188 0 114.573029 164.3907207 0.888691798 1.011816732 0.851712243 1.046320192 0.842977084 0.364519789 0.710175048 0 0.696955573 1 7.360985056 -4.673028052 0.848525454 0.955319771 1.02E-14 0.681165539 0.176025478 0.492403841 0.375443537 0.023098733 0.382381506 2.12E-05 4.673028052 -0.955319771 SAMPFTAS(ph)PASSTTAR ddPTM_HeLa_Curcumin_4h_R1 3 SAMPFTASPASSTTAR 16 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 0 SAMPFT(0.1)AS(0.668)PAS(0.024)S(0.124)T(0.042)T(0.042)AR;SAMPFT(0.158)AS(0.709)PAS(0.036)S(0.085)T(0.006)T(0.006)AR;SAMPFT(0.124)AS(0.865)PAS(0.001)S(0.008)T(0.001)T(0.001)AR ;; 110.6 0.0018455 254467000 8094.4 6741.2 7032.7 7386.3 7681 12317.8 11295.2 5607.1 8695.9 5997.8 TRUE FALSE FALSE 7453.719699 7323.87929 7293.338049 7355.737448 7589.409092 9762.94943 11612.11291 7316.678978 7741.981526 6206.223104 1.201007372 1.180086369 1.175165302 1.18521963 1.222870813 1.573090311 1.871043422 1.178926193 1.247454595 1 12.59949984 -5.364749242 3.139864071 1.11827168 1.576912983 0.477688641 0.171672077 0.132407934 2.479839567 0.023896648 0.05904788 4.32E-06 5.364749242 0.458641303 SAMPFTASPASS(ph)TTAR ddPTM_HeLa_Curcumin_4h_R1 1 SAMPFTASPASSTTAR 16 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 0 S(0.001)AMPFT(0.007)AS(0.247)PAS(0.079)S(0.501)T(0.158)T(0.008)AR 113.67 0.0015741 157440000 4571.4 3623.9 3713.6 4080.3 3749.9 6571.9 6185.4 2532.3 4469.7 2320.1 TRUE FALSE FALSE 4209.568866 3937.133768 3851.229283 4063.4168 3705.184892 5208.813859 6358.945677 3304.386613 3979.385093 2400.723302 1.753458577 1.639978153 1.604195402 1.69258023 1.543361906 2.169685217 2.648762425 1.376412938 1.657577568 1 11.22925342 -10.39264926 0.183389864 2.60E-14 2.121756386 0.153193815 0.3856979 10.65757617 0.362779237 5.405785745 0.597072198 4.05E-11 10.39264926 2.121756386 SANAFLTPS(ph)YTWTPLKTEVDESQATK ddPTM_HeLa_Curcumin_4h_R1 1 SANAFLTPSYTWTPLKTEVDESQATK 26 1 Q15398-1;Q15398-3;Q15398 Q15398-1 DLGAP5 Disks large-associated protein 5 1 0 SANAFLT(0.021)PS(0.332)Y(0.29)T(0.072)WT(0.254)PLKT(0.021)EVDES(0.01)QAT(0.001)K 69.248 0.00027768 26450000 947.98 624.59 1071.3 912.27 982.88 1916.2 2022.7 611.29 1134.3 702.82 TRUE FALSE FALSE 872.9463827 678.5767765 1111.00332 908.4952685 971.1597979 1518.75852 2079.451518 797.669507 1009.870128 727.2429427 1.200350435 0.933081281 1.52769213 1.249232155 1.335399412 2.088378492 2.859362939 1.096840492 1.388628295 1 9.506293581 -5.344931364 3.435536766 1.133579103 2.105232426 0.3941359 0.434121519 0.140041134 3.161069277 0.056361377 0.137858448 4.52E-06 5.344931364 0.971653323 SANGGSES(ph)DGEENIGWSTVNLDEEK ddPTM_HeLa_Curcumin_4h_R1 1 SANGGSESDGEENIGWSTVNLDEEK 25 0 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 1 0 S(0.01)ANGGS(0.291)ES(0.699)DGEENIGWSTVNLDEEK 105.19 1.69E-07 4052100 3556.8 3659.2 3499.1 3338.7 4238.6 3909.5 3282.8 2387.9 3632.4 3154.9 TRUE FALSE FALSE 3275.275527 3975.484943 3628.779724 3324.885344 4188.057463 3098.625631 3374.906533 3115.959717 3233.934808 3264.53254 1.003290819 1.217780768 1.111577134 1.018487426 1.282896529 0.949178969 1.033810045 0.954488791 0.990627224 1 11.67266071 -7.457577519 24.99998559 1.001450956 1.08291719 0.126438791 0.100031517 301.0184512 115242.4325 0.016504586 0.018872714 3.49E-08 7.457577519 0.081466234 SANPPHTIQAS(ph)EEQSSTPAPVKK ddPTM_HeLa_Curcumin_4h_R1 1 SANPPHTIQASEEQSSTPAPVKK 23 1 Q9Y450-4;Q9Y450;E9PS53;E9PHZ9;B7Z524;H0YDX7;J3QT46 Q9Y450-4 HBS1L HBS1-like protein 1 0 SANPPHT(0.006)IQAS(0.716)EEQS(0.099)S(0.079)T(0.099)PAPVKK 55.208 0.011519 10248000 4087.3 3559.4 3568.9 3903.2 4935.6 8821.1 6288.2 2444.8 4710.8 3474.3 TRUE FALSE FALSE 3763.785892 3867.058676 3701.166574 3887.049593 4876.746194 6991.504426 6464.629968 3190.208266 4194.037026 3595.031666 1.046940957 1.075667486 1.029522663 1.081228193 1.356523849 1.944768523 1.798212246 0.887393648 1.166620329 1 11.81178876 -5.644537967 3.502483 1.03046031 1.579039211 0.396336008 0.262671867 0.14511601 3.455313354 0.035790208 0.075133269 2.27E-06 5.644537967 0.548578901 SAPALPVSEDFKSEPVS(ph)PQDFSFSK ddPTM_HeLa_Curcumin_4h_R1 2 SAPALPVSEDFKSEPVSPQDFSFSK 25 1 P48552 P48552 NRIP1 Nuclear receptor-interacting protein 1 1 0 S(0.002)APALPVS(0.085)EDFKS(0.03)EPVS(0.873)PQDFS(0.009)FS(0.001)K;SAPALPVS(0.07)EDFKS(0.392)EPVS(0.489)PQDFS(0.046)FS(0.002)K ; 69.439 0.0014471 0 1342.18 1041.36 1062.11 1117.79 1206.34 1384.96 1430.11 543.51 1469.59 1210.3 TRUE FALSE FALSE 1235.945037 1131.370518 1101.472731 1113.164881 1191.955183 1097.703684 1470.235038 709.223697 1308.379654 1252.357835 0.986894482 0.903392374 0.879519176 0.888855286 0.951768856 0.876509615 1.173973601 0.566310744 1.044733076 1 10.29043113 -4.242167053 24.75294075 0.971436709 0.566310325 0.653207617 0.08760417 1749.452254 2246919.048 0.011270066 0.558234803 5.73E-05 4.242167053 -0.405126385 SAPAMQSSGS(ph)FNYARPK ddPTM_HeLa_Curcumin_4h_R1 2 SAPAMQSSGSFNYARPK 17 1 Q8WX93-3;Q8WX93;Q8WX93-4;A0A3B3ISX8 Q8WX93-3 PALLD Palladin 1 0 SAPAMQS(0.011)S(0.245)GS(0.744)FNYARPK;SAPAMQSS(0.169)GS(0.831)FNYARPK ; 131.86 0.00015088 99823000 2741.3 2340.5 3056.2 3005.8 2717.9 3181.2 2643.4 2528.7 2463.05 2999.8 TRUE FALSE FALSE 2524.323212 2542.802391 3169.465461 2993.362796 2685.490818 2521.38326 2717.56669 3299.688989 2192.859577 3104.042827 0.813237237 0.819190499 1.021076589 0.964343266 0.865159074 0.812290101 0.875492653 1.063029466 0.706452746 1 11.59993275 -9.636480632 1.486858795 0.999537925 0.888678191 0 0.123984698 0.567864812 2.271172089 0.061221301 0.014173228 2.31E-10 9.636480632 -0.110859733 SAPAPK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 SAPAPKK 7 1 P33778;P58876;P62807;P57053;O60814;Q16778;P06899;Q5QNW6;Q5QNW6-2;Q8N257;Q93079;U3KQK0;Q99877;Q99880 P33778;P58876;P62807;Q16778;Q5QNW6;Q8N257;Q93079;U3KQK0;Q99880 HIST1H2BB;HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST2H2BF;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BL Histone H2B type 1-B;Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 2-F;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-L 0 1 ; SAPAPK(1)K;SAPAPK(1)K 91.041 0.010186 7365000 7969.5 12269.5 6157.3 5052.5 4731.1 6200.6 6052.5 3159.9 4007.4 5464 FALSE TRUE FALSE 7338.705666 13330.02091 6385.494955 5031.594094 4674.684722 4914.525665 6222.316861 4123.338964 3567.798246 5653.873593 1.297996063 2.35767933 1.12940179 0.889937493 0.826810972 0.869231613 1.100540498 0.729294509 0.631036083 1 12.46502391 -6.351446785 5.158928634 1.256734172 0.892093804 0.187522265 0.418762586 0.329151206 14.39089878 0.062630295 0.096585723 4.45E-07 6.351446785 -0.364640368 SAPAPK(ac)K(ac)GSK ddPTM_HeLa_Curcumin_4h_R1 2 SAPAPKKGSK 10 2 P33778;P58876;P62807;P57053;O60814;Q16778;P06899;Q5QNW6;Q5QNW6-2;Q8N257;Q93079;U3KQK0;Q99877;Q99880 P33778;P58876;P62807;Q16778;Q5QNW6;Q8N257;Q93079;U3KQK0;Q99880 HIST1H2BB;HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST2H2BF;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BL Histone H2B type 1-B;Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 2-F;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-L 0 2 ; SAPAPK(1)K(1)GSK;SAPAPK(1)K(1)GSK 136.5 7.69E-05 111291000 17920.7 12313.2 15687.7 15420.3 16132.9 18658.7 16078.3 8674.1 15898.9 13595 FALSE TRUE FALSE 16502.25769 13377.49814 16269.09996 15356.49488 15940.5257 14788.67529 16529.41383 11318.79316 14154.83045 14067.42524 1.17308302 0.950955695 1.15650872 1.091635081 1.13315162 1.051270936 1.175013447 0.804610152 1.006213305 1 13.78007068 -4.250022501 24.82400367 1.086243715 0.804609969 0.5524706 0.074804089 943.5579196 2051560.045 0.010775072 0.223978142 5.62E-05 4.250022501 -0.281633746 SAPAPK(ac)K(ac)GSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 SAPAPKKGSKK 11 3 P33778;P58876;P62807;P57053;O60814;Q16778;P06899;Q5QNW6;Q5QNW6-2;Q8N257;Q93079;U3KQK0;Q99877;Q99880 P33778;P58876;P62807;Q16778;Q5QNW6;Q8N257;Q93079;U3KQK0;Q99880 HIST1H2BB;HIST1H2BD;HIST1H2BC;H2BFS;HIST1H2BK;HIST2H2BE;HIST1H2BJ;HIST2H2BF;HIST3H2BB;HIST1H2BH;HIST1H2BN;HIST1H2BL Histone H2B type 1-B;Histone H2B type 1-D;Histone H2B type 1-C/E/F/G/I;Histone H2B type F-S;Histone H2B type 1-K;Histone H2B type 2-E;Histone H2B type 1-J;Histone H2B type 2-F;Histone H2B type 3-B;Histone H2B type 1-H;Histone H2B;Histone H2B type 1-N;Histone H2B type 1-L 0 3 ; SAPAPK(1)K(1)GSK(1)K;SAPAPK(1)K(1)GSK(1)K 159.44 5.49E-08 682800000 17849 12998.6 15356 14958.8 15506.5 19891.2 17345.6 8943 16141.6 12273.1 FALSE TRUE FALSE 16436.23282 14122.14106 15925.10687 14896.90445 15321.59512 15765.5409 17832.27085 11669.67953 14370.90686 12699.58931 1.294233413 1.112015571 1.253985974 1.173022535 1.206463826 1.241421318 1.404161222 0.918902119 1.131604063 1 13.63249422 -9.454611325 1.123534862 0.996960608 1.215230189 0.11585035 0.126299554 0.467642084 1.032034944 0.081665004 0.019125434 3.51E-10 9.454611325 0.218269581 SAPASPTHPGLMS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SAPASPTHPGLMSPR 15 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 0 SAPAS(0.007)PT(0.093)HPGLMS(0.9)PR 107.45 0.0029135 9405400 2514.3 1923.6 1441.6 1579.9 2089.9 2897.7 1592.2 1127.4 3107.4 1718.7 TRUE FALSE FALSE 2315.290502 2089.867413 1495.026964 1573.362792 2064.979307 2296.684356 1636.872847 1471.13907 2766.525994 1778.424697 1.301877165 1.175122802 0.840646763 0.884694637 1.161128335 1.291415015 0.920406048 0.82721471 1.5556048 1 10.79638417 -6.815311246 24.99996648 1.148979047 1.001551491 0.241868629 0.199401645 144.9058349 67244.8494 0.029394166 0.038631522 1.53E-07 6.815311246 -0.147427556 EGRPPEPTPAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 EGRPPEPTPAKR 12 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 1 ; EGRPPEPTPAK(1)R;EGRPPEPTPAK(1)R 122.18 0.0002103 49079000 4312 3766.3 3304.2 3496.5 4058.2 5626.2 4434.1 7669.1 4693.6 2819.2 FALSE TRUE FALSE 3970.70065 4091.84219 3426.656559 3482.032409 4009.808615 4459.2627 4558.508912 10007.37329 4178.723823 2917.16699 1.361149589 1.402676708 1.174652178 1.193634928 1.374555735 1.528627848 1.562649285 3.430510944 1.432459587 1 11.51035226 -2.167738439 1.061859772 1.205161196 199.9999999 0.938243715 0.161226669 25.26029219 0.403333385 0.026914856 11823.74353 0.006796128 2.167738439 198.7948387 up SAPGST(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 1 SAPGSTPVR 9 0 F5H1D6;Q07864;A0A087WW42;A0A087WX51 F5H1D6 POLE DNA polymerase;DNA polymerase epsilon catalytic subunit A 1 0 SAPGS(0.044)T(0.956)PVR 120.27 0.017871 23286000 4989.9 4262.5 4611.6 4689.4 4341.5 6052.3 4434.2 1962.7 5137.7 5467.3 TRUE FALSE FALSE 4594.94415 4630.931507 4782.509953 4669.996505 4289.730448 4796.984757 4558.611718 2561.118195 4574.107164 5657.288268 0.812216725 0.818577963 0.845371444 0.825483215 0.758266195 0.847930056 0.805794491 0.452711277 0.808533514 1 12.46589497 -2.385931475 0.079862397 1.189970643 4.71E-16 0.36148183 0.1035391 78.96735424 0.617364118 1.828578807 10.8236354 0.004112146 2.385931475 -1.189970643 SAPGST(ph)PVRR ddPTM_HeLa_Curcumin_4h_R1 1 SAPGSTPVRR 10 1 F5H1D6;Q07864;A0A087WW42;A0A087WX51 F5H1D6 POLE DNA polymerase;DNA polymerase epsilon catalytic subunit A 1 0 SAPGS(0.04)T(0.96)PVRR 96.334 0.0078572 2176000 508.23 315.24 547.16 334.94 581.18 792.07 434.69 337.8 627.34 576.54 TRUE FALSE FALSE 468.0030592 342.4879409 567.4382309 333.554107 574.2498081 627.7857535 446.8862315 440.793665 558.5223715 596.5747221 0.784483556 0.574090601 0.951160366 0.559115388 0.962578176 1.052317053 0.74908677 0.738874191 0.936215282 1 9.220559039 -9.1213766 0.988712257 0.994828592 0.800557469 0.163876717 0.152363967 0.671086963 1.226389727 0.086009364 0.027893405 7.56E-10 9.1213766 -0.194271123 SAPS(ph)SPAPR ddPTM_HeLa_Curcumin_4h_R1 2 SAPSSPAPR 9 0 E9PAK5;O75064 E9PAK5 DENND4B DENN domain-containing protein 4B 1 0 S(0.001)APS(0.499)S(0.499)PAPR;S(0.002)APS(0.499)S(0.499)PAPR ; 101.66 0.012154 52457000 11557.9 10974 11969.3 10918.6 11467.6 11395.2 8499.3 7356.6 12037.9 12348.7 TRUE FALSE FALSE 10643.08002 11922.54366 12412.89279 10873.42173 11330.85636 9031.70707 8737.767483 9599.593474 10717.37249 12777.81641 0.832934179 0.933065814 0.971440847 0.850960867 0.886759991 0.706827112 0.683823214 0.751270262 0.838748355 1 13.6413537 -5.349721221 2.535714089 0.919852429 0.706745001 0.698019034 0.055928756 0.135793659 1.690146866 0.010001381 0.026522353 4.47E-06 5.349721221 -0.213107428 SAPT(ph)SPTATNISSK ddPTM_HeLa_Curcumin_4h_R1 1 SAPTSPTATNISSK 14 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 0 SAPT(0.949)S(0.05)PTATNISSK 207.52 8.73E-09 17719000 4296.9 3814.8 3538.7 3472.7 3658.7 4632.4 3866.7 4229.4 4754.3 3568.2 TRUE FALSE FALSE 3956.795831 4144.534314 3669.847335 3458.330888 3615.072392 3671.588022 3975.189195 5518.92459 4232.765185 3692.194684 1.071665004 1.122512399 0.993947408 0.93665995 0.979112073 0.994418858 1.076646693 1.494754492 1.146408992 1 11.85026291 -4.26300789 3.732970968 1.025156876 1.543596763 0.830948577 0.06237527 0.067800609 1.774799051 0.007779352 0.096532709 5.46E-05 4.26300789 0.518439888 NVFEVGPGDS(ph)PTFPR ddPTM_HeLa_Curcumin_4h_R1 2 NVFEVGPGDSPTFPR 15 0 Q16584;Q16584-2 Q16584 MAP3K11 Mitogen-activated protein kinase kinase kinase 11 1 0 NVFEVGPGDS(0.829)PT(0.171)FPR;NVFEVGPGDS(0.773)PT(0.227)FPR ; 216.77 6.90E-42 2941000 6120.3 4755.45 4616.96 5230.84 4758.38 5906.5 3577.02 1272.23 6068.8 4713.14 TRUE FALSE FALSE 5635.871797 5166.489908 4788.068599 5209.19617 4701.639426 4681.42532 3677.381554 1660.12707 5403.067823 4876.921264 1.15562083 1.059375296 0.981780992 1.068132104 0.964058916 0.959914066 0.754037507 0.340404731 1.107884981 1 12.25175497 -4.240886662 1.14917952 1.063409506 4.16E-22 0.945574486 0.052465249 0.330215256 0.339995557 0.010091115 0.426109492 5.74E-05 4.240886662 -1.063409506 down TYSAPAINAIQGGSFES(ph)PKKEK ddPTM_HeLa_Curcumin_4h_R1 1 TYSAPAINAIQGGSFESPKKEK 22 2 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 0 TYSAPAINAIQGGS(0.062)FES(0.938)PKKEK 92.133 8.24E-05 76339000 4393.1 3426.6 3864.3 4191.3 3567.7 4279.4 2589 1060.8 3995.8 3682.9 TRUE FALSE FALSE 4045.381499 3722.780035 4007.514357 4173.957511 3525.157508 3391.804201 2661.640372 1384.233037 3557.470737 3810.880501 1.061534598 0.976881861 1.051598012 1.095273785 0.925024415 0.890031635 0.698431864 0.363231814 0.933503618 1 11.89590865 -4.240198352 1.01602417 1.030284791 8.48E-22 0.942266476 0.050039817 0.247507696 0.190939598 0.006377639 0.279544112 5.75E-05 4.240198352 -1.030284791 down SAPTS(ph)PTATNISSK ddPTM_HeLa_Curcumin_4h_R1 1 SAPTSPTATNISSK 14 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 0 SAPT(0.079)S(0.918)PT(0.002)ATNISSK 209.11 2.13E-09 28302000 2439.5 1771.6 1744.6 2271.1 1783 2483.6 2038.6 2000.2 2383.4 1962.3 TRUE FALSE FALSE 2246.411001 1924.72921 1809.256411 2261.70279 1761.73889 1968.473364 2095.797629 2610.051772 2121.946983 2030.489779 1.106339477 0.947913764 0.891044333 1.113870561 0.867642333 0.969457411 1.032163595 1.285429653 1.045041943 1 10.98761205 -4.263439911 5.403321405 1.019129434 1.295421287 0.522562985 0.080325038 0.104090824 11.20874962 0.011972871 0.106069541 5.45E-05 4.263439911 0.276291853 SAQGSSS(ph)PVPSMVQK ddPTM_HeLa_Curcumin_4h_R1 2 SAQGSSSPVPSMVQK 15 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3;A0A0A0MSW3;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 0 SAQGSS(0.022)S(0.805)PVPS(0.173)MVQK;SAQGSS(0.03)S(0.707)PVPS(0.263)MVQK ; 144.4 0.00058046 84191000 11327.9 9346.7 10105.1 10008.7 8978.8 8655.3 8074.6 7147.5 11187.8 9246.6 TRUE FALSE FALSE 10431.28476 10154.5871 10479.6039 9967.286651 8871.733674 6860.093215 8301.151544 9326.739847 9960.52633 9567.918662 1.090235518 1.061316203 1.095285638 1.04174032 0.927237573 0.716989082 0.867602646 0.97479297 1.041033759 1 13.22398941 -5.635803215 3.808944588 1.049561044 0.850293799 0.673167935 0.063810822 0.106364929 2.911289148 0.00991319 0.020652111 2.31E-06 5.635803215 -0.199267245 SAQGSSS(ph)PVPSMVQKS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SAQGSSSPVPSMVQKSPR 18 1 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3;A0A0A0MSW3;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 2 0 SAQGS(0.002)S(0.126)S(0.87)PVPS(0.012)MVQKS(0.99)PR 107.18 0.0013799 9155000 5160.2 4318.6 5155 5342.5 4389.5 5023.6 4113.6 3057.7 6061.9 4954.4 TRUE FALSE FALSE 4751.764725 4691.880541 5346.048835 5320.394151 4337.158079 3981.648732 4229.016545 3989.978654 5396.924736 5126.565031 0.926890559 0.915209407 1.042813034 1.03780877 0.846016398 0.776669897 0.824922052 0.778294751 1.052737009 1 12.32377678 -5.603633462 5.426201395 0.971201152 0.798582656 0.779134174 0.048882678 0.076252645 3.817803203 0.00697415 0.014170816 2.49E-06 5.603633462 -0.172618495 SAQGSSSPVPS(ph)MVQK ddPTM_HeLa_Curcumin_4h_R1 2 SAQGSSSPVPSMVQK 15 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3;A0A0A0MSW3;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 0 SAQGSS(0.014)S(0.107)PVPS(0.879)MVQK;SAQGSS(0.035)S(0.317)PVPS(0.649)MVQK ; 129.82 0.00084652 41075000 7544.5 6188.5 6298.6 6633.8 5568.4 6009.5 5618.2 5623.2 6775.2 5907.4 TRUE FALSE FALSE 6947.344864 6723.406365 6532.031657 6606.351093 5502.000467 4763.061959 5775.831571 7337.687794 6031.977511 6112.68171 1.13654615 1.099911084 1.068603269 1.080761506 0.900096018 0.779209876 0.944893231 1.200404036 0.986797251 1 12.57758973 -5.770399614 24.96118621 1.070295272 0.94270804 0.186985137 0.105948795 206.061442 574041.7654 0.016078294 0.02945603 1.70E-06 5.770399614 -0.127587231 SAQGSSSPVPSMVQKS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 SAQGSSSPVPSMVQKSPR 18 1 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3;A0A0A0MSW3;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 0 SAQGSSSPVPS(0.17)MVQKS(0.83)PR;SAQGS(0.005)S(0.026)S(0.076)PVPS(0.369)MVQKS(0.524)PR ; 126.3 9.73E-05 85720000 10388.6 8494.9 8978.3 9088.2 7989.7 6424.2 3068.4 4263.4 9932.9 8188.1 TRUE FALSE FALSE 9566.331348 9229.161303 9311.043696 9050.595436 7894.428046 5091.748504 3154.491046 5563.291034 8843.285721 8472.635866 1.129085623 1.089290446 1.098954781 1.068214848 0.931755852 0.600963925 0.372315192 0.656618687 1.0437467 1 13.04859515 -5.308628281 2.537869713 1.067622659 0.505840376 0.913988341 0.072728193 0.057364006 0.719685655 0.011049488 0.030181167 4.91E-06 5.308628281 -0.561782283 SAQPASAEPR ddPTM_HeLa_Curcumin_4h_R1 1 SAQPASAEPR 10 0 Q9Y490 Q9Y490 TLN1 Talin-1 0 0 135.43 0.00071378 1813600 1351.1 1212.7 1254 1082.4 1307.2 1583.8 1147.7 997.67 1267.5 1245.3 FALSE FALSE TRUE 1244.159009 1317.520384 1300.474343 1077.921316 1291.612494 1255.302027 1179.901373 1301.85499 1128.458421 1288.574082 0.965531611 1.022463824 1.009235217 0.83652258 1.002357964 0.974179168 0.915664368 1.01030667 0.875741982 1 10.33155977 SAQQEASADVAT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SAQQEASADVATPK 14 0 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 0 SAQQEAS(0.001)ADVAT(0.999)PK;SAQQEASADVAT(1)PK ; 197.75 5.60E-06 40143000 3071.3 2590.16 2424.7 3067.4 3232.9 5446.5 4741.5 1377.79 3645.5 2267.46 TRUE FALSE FALSE 2828.203364 2814.041889 2514.561515 3054.707912 3194.349779 4316.834505 4874.533729 1797.871828 3245.597771 2346.254066 1.205412238 1.199376457 1.071734537 1.301951036 1.361467978 1.839883654 2.077581366 0.766273293 1.383310451 1 11.19614353 -5.757681578 2.105776911 1.109226023 1.604470062 0.17228857 0.334101865 0.271432565 2.452940289 0.046063331 0.100881333 1.75E-06 5.757681578 0.495244039 SAS(ph)ADNLTLPR ddPTM_HeLa_Curcumin_4h_R1 1 SASADNLTLPR 11 0 Q8ND76-3;Q8ND76-2;Q8ND76 Q8ND76-3 CCNY Cyclin-Y 1 0 S(0.335)AS(0.664)ADNLT(0.001)LPR 118.08 0.0044492 29387000 943.08 1005 868.56 1215.5 852.78 1451.4 1123.3 301.48 1372.2 1144.6 TRUE FALSE FALSE 868.4342229 1091.867722 900.7495977 1210.470583 842.6111555 1150.363279 1154.816775 393.3998642 1221.673093 1184.374765 0.733242761 0.921893774 0.760527516 1.022033413 0.711439639 0.971283173 0.975043381 0.332158263 1.031491998 1 10.20990994 -9.490219519 1.183523175 1.001936507 0.812055213 0.163533725 0.18951533 0.812581435 2.002849238 0.128024538 0.029899824 3.23E-10 9.490219519 -0.189881294 SAS(ph)DTNLQK ddPTM_HeLa_Curcumin_4h_R1 1 SASDTNLQK 9 0 A0A0C4DGH6;A0JNW5 A0A0C4DGH6 UHRF1BP1L UHRF1-binding protein 1-like 1 0 S(0.018)AS(0.91)DT(0.073)NLQK 108.7 0.0095709 23289000 2166.5 3755.6 2156.7 2334.1 1618 3078.1 1871 2569.2 3164.1 4080.7 TRUE FALSE FALSE 1995.019239 4080.217329 2236.629199 2324.442113 1598.706407 2439.667363 1923.495224 3352.537253 2817.006146 4222.504021 0.472473023 0.966302769 0.529692616 0.550489023 0.378615722 0.577777392 0.455534255 0.79396899 0.66714114 1 12.04388308 -9.506932417 0.761652056 1.06360833 0.573560723 0.101932471 0.193048397 0.654759039 0.528365585 0.215839889 0.03162078 3.11E-10 9.506932417 -0.490047608 SAS(ph)EPSLHR ddPTM_HeLa_Curcumin_4h_R1 3 SASEPSLHR 9 0 H7C155;P04049;P04049-2;Q96II5;P10398 H7C155;Q96II5 RAF1;ARAF RAF proto-oncogene serine/threonine-protein kinase;Serine/threonine-protein kinase A-Raf 1 0 S(0.007)AS(0.993)EPSLHR;S(0.026)AS(0.974)EPSLHR;S(0.029)AS(0.971)EPSLHR ;; 100.82 0.005732 75245000 8595.17 7690.18 7055.93 6238.65 11432.91 16117.44 8655.51 4894.22 10922.27 8240.9 TRUE FALSE FALSE 7914.853225 8354.884892 7317.428973 6212.836119 11296.58002 12774.50126 8898.360315 6386.445148 9724.124307 8527.270662 0.928181307 0.97978418 0.858120876 0.72858437 1.324759171 1.498076204 1.043517987 0.748943642 1.140356005 1 13.05786833 -5.752108193 24.99955275 0.942596596 1.170534622 0.205912647 0.205395498 231.0109921 618905.7299 0.029066162 0.057510148 1.77E-06 5.752108193 0.227938027 SAS(ph)EPSLNR ddPTM_HeLa_Curcumin_4h_R1 1 SASEPSLNR 9 0 H7C560;A0A2U3TZI2;A0A2R8Y8E0;P15056 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 0 S(0.029)AS(0.92)EPS(0.051)LNR 117.02 0.0070063 144580000 2169.3 1495.3 1798.4 1770.4 2037.7 2225.3 1921.7 1638 2142.3 1792 TRUE FALSE FALSE 1997.597616 1624.547069 1865.050286 1763.074554 2013.401758 1763.747696 1975.61773 2137.41866 1907.29505 1854.271867 1.077294895 0.876110509 1.00581275 0.950817723 1.085817994 0.951180745 1.065441247 1.152699719 1.028595151 1 10.85663707 -4.391350247 3.525846694 1.016195813 1.153719129 0.354263859 0.06129696 0.241053911 4.810566607 0.008792217 0.068927243 4.06E-05 4.391350247 0.137523316 GCDS(ph)PDPDTSYVLTPHTEEK ddPTM_HeLa_Curcumin_4h_R1 1 GCDSPDPDTSYVLTPHTEEK 20 0 Q02078-3;Q02078-5;Q02078 Q02078-3 MEF2A Myocyte-specific enhancer factor 2A 1 0 GCDS(0.999)PDPDT(0.001)SYVLTPHTEEK 193.36 1.09E-10 100540000 4440.1 3467.1 3814 3892.1 3819.2 4815.7 3075.4 835.56 4457.8 4070.7 TRUE FALSE FALSE 4088.6614 3766.780675 3955.350195 3875.995521 3773.658534 3816.869536 3161.687447 1090.318398 3968.790493 4212.156522 0.97068126 0.894264174 0.939032103 0.920192662 0.895897034 0.906155675 0.750610152 0.258850399 0.942222938 1 12.04034333 -4.240191099 1.616883817 0.964079077 3.91E-15 0.965942358 0.038042207 0.15470222 0.363385993 0.006711634 0.237000194 5.75E-05 4.240191099 -0.964079077 down SAS(ph)LSHPGGEGEPAR ddPTM_HeLa_Curcumin_4h_R1 1 SASLSHPGGEGEPAR 15 0 C9JXU1;A6NN40;Q2M3G4-2;Q2M3G4 C9JXU1 SHROOM1 Protein Shroom1 1 0 S(0.029)AS(0.936)LS(0.035)HPGGEGEPAR 112.96 0.0028672 0 1250.6 947.85 961.15 1182.9 1038.4 1252.2 949.09 563.77 1154.4 1090.8 TRUE FALSE FALSE 1151.61369 1029.77793 996.7710645 1178.005473 1026.017758 992.4796048 975.7189111 735.6608777 1027.765208 1128.705219 1.02029624 0.912353299 0.883110176 1.043678592 0.909021896 0.879308068 0.86445858 0.651774144 0.910570086 1 10.14045303 -3.331545442 0.525568029 1.000479543 1.01E-22 0.668945349 0.059932007 3.127732711 0.286308932 0.010329168 2.402161086 0.000466074 3.331545442 -1.000479543 SAS(ph)PDDDLGS(ph)SNWEAADLGNEERK ddPTM_HeLa_Curcumin_4h_R1 2 SASPDDDLGSSNWEAADLGNEERK 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 2 0 S(0.163)AS(0.869)PDDDLGS(0.798)S(0.17)NWEAADLGNEERK;S(0.059)AS(0.947)PDDDLGS(0.497)S(0.497)NWEAADLGNEERK ; 92.805 1.77E-05 3604700 2322.47 1776.85 1967.31 2392.95 1976.8 2277.62 1689.97 1126.56 2626.24 2130.04 TRUE FALSE FALSE 2138.644049 1930.432997 2040.220239 2383.048607 1953.227951 1805.215938 1737.38601 1470.042958 2338.148043 2204.058731 0.970320808 0.875853701 0.925665097 1.081209213 0.886195963 0.819041667 0.788266658 0.666970865 1.060837449 1 11.10594695 -4.847160834 1.015049464 0.97825081 0.649922633 0.740569281 0.061937286 0.316129058 0.437672546 0.008955637 0.089849773 1.42E-05 4.847160834 -0.328328177 SAS(ph)PDDDLGSSNWEAADLGNEER ddPTM_HeLa_Curcumin_4h_R1 3 SASPDDDLGSSNWEAADLGNEER 23 0 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 0 S(0.211)AS(0.789)PDDDLGSSNWEAADLGNEER;S(0.418)AS(0.582)PDDDLGSSNWEAADLGNEER;S(0.161)AS(0.839)PDDDLGSSNWEAADLGNEER ;; 210.96 8.98E-19 487190100 3448.24 3376.2 2846.34 3498.66 3057.17 3337.65 2719.03 2230.96 3442.76 3006.95 TRUE FALSE FALSE 3175.308165 3668.023684 2951.827864 3484.183472 3020.715244 2645.383767 2795.318664 2911.169434 3065.097841 3111.441289 1.020526461 1.1788825 0.948701129 1.119797274 0.970841152 0.850211693 0.898399939 0.935633735 0.985105473 1 11.60336731 -5.518135652 24.87223695 1.026596823 0.897682393 0.490308794 0.066411633 124.8448296 654670.4495 0.009076854 0.018553099 3.03E-06 5.518135652 -0.12891443 SAS(ph)PDDDLGSSNWEAADLGNEERK ddPTM_HeLa_Curcumin_4h_R1 5 SASPDDDLGSSNWEAADLGNEERK 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 0 S(0.029)AS(0.441)PDDDLGS(0.44)S(0.09)NWEAADLGNEERK;S(0.036)AS(0.964)PDDDLGSSNWEAADLGNEERK;S(0.041)AS(0.958)PDDDLGSSNWEAADLGNEERK;S(0.019)AS(0.975)PDDDLGS(0.002)S(0.004)NWEAADLGNEERK;S(0.027)AS(0.699)PDDDLGS(0.263)S(0.01)NWEAADLGNEERK ;;;; 186.27 5.27E-12 2559518000 8632.1 7789.2 8076.2 8359.7 7459.8 8485.6 6624.95 6345.6 11155.9 9119.2 TRUE FALSE FALSE 7948.860176 8462.46374 8375.511077 8325.109776 7370.846757 6725.590908 6810.828267 8280.344228 9932.125681 9436.091521 0.84238905 0.896818743 0.887603841 0.882262509 0.781133453 0.712751767 0.721784889 0.877518431 1.052567756 1 13.2039737 -13.52287874 0.095846767 1.625878899 0.667936594 0.672230805 0.059115042 64.26415836 0.462604367 8.121989354 0.598598078 3.00E-14 13.52287874 -0.957942305 SAS(ph)PDYNR ddPTM_HeLa_Curcumin_4h_R1 3 SASPDYNR 8 0 Q14669;Q14669-2;Q14669-3;G5E9G6;F8W9P3;C9JLJ5;C9JSX9;C9JLD7 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 0 S(0.038)AS(0.953)PDY(0.009)NR;S(0.009)AS(0.991)PDYNR;SAS(1)PDYNR ;; 122.96 0.0073495 233516000 16958.6 15629.9 16869.5 17973.5 17506.6 18662.9 14159.5 8692.2 18412.9 15901.4 TRUE FALSE FALSE 15616.30892 16980.87891 17494.69851 17899.13042 17297.84523 14792.00417 14556.77746 11342.41177 16393.05094 16453.97247 0.949090498 1.032023054 1.063250747 1.087830337 1.051286871 0.898992884 0.884696841 0.689341847 0.996297458 1 14.00614831 -4.30086201 1.363083844 0.99779927 0.580880333 0.807730149 0.049205816 0.480410886 0.814008074 0.008607216 0.269324306 5.00E-05 4.30086201 -0.416918938 SAS(ph)PDYNRTNS(ph)PSSAK ddPTM_HeLa_Curcumin_4h_R1 2 SASPDYNRTNSPSSAK 16 1 Q14669;Q14669-2;Q14669-3;G5E9G6;F8W9P3;C9JLJ5;C9JSX9;C9JLD7 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 2 0 S(0.186)AS(0.814)PDYNRT(0.005)NS(0.475)PS(0.475)S(0.044)AK;S(0.002)AS(0.998)PDYNRT(0.003)NS(0.793)PS(0.175)S(0.03)AK ; 185.28 2.58E-05 26378000 7302.7 4239.5 5333.8 7070.7 4588.3 7081.5 4597 2014.4 9476.1 7290.7 TRUE FALSE FALSE 6724.683589 4605.943489 5531.47532 7041.443317 4533.587519 5612.717075 4725.979448 2628.581287 8436.595538 7544.051282 0.891388902 0.61053979 0.733223452 0.933376916 0.600948661 0.743992434 0.62645113 0.348430994 1.118311001 1 12.88112377 -4.114784401 0.194520933 1.047655724 9.32E-15 0.670991991 0.124237764 7.38859026 0.247394337 0.162363028 1.93543842 7.68E-05 4.114784401 -1.047655724 SPSAS(ph)SVGSR ddPTM_HeLa_Curcumin_4h_R1 1 SPSASSVGSR 10 0 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 0 S(0.066)PS(0.279)AS(0.587)S(0.068)VGSR 95.477 0.015578 28457000 2181.3 1619.6 1861.4 1814.9 1819.4 1709.6 1342.8 490.74 2455.9 1754.3 TRUE FALSE FALSE 2008.647803 1759.591007 1930.385121 1807.390425 1797.704843 1355.009689 1380.475354 640.3643669 2186.493914 1815.261794 1.106533399 0.969331814 1.063419683 0.995663783 0.990328144 0.746454144 0.76048279 0.35276695 1.204506105 1 10.82596191 -4.236915128 0.786299736 1.046770562 2.15E-17 0.885331589 0.078186861 0.493736901 0.21181233 0.010043961 0.455737496 5.80E-05 4.236915128 -1.046770562 down REVS(ph)PPGAR ddPTM_HeLa_Curcumin_4h_R1 1 REVSPPGAR 9 1 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 REVS(1)PPGAR 97.911 0.0067278 5916600 1573.6 1473.3 1221.4 1320.7 1437.5 1353.6 914.92 455.41 1626.9 1366.3 TRUE FALSE FALSE 1449.0479 1600.645487 1266.666158 1315.235293 1420.358751 1072.848102 940.5901928 594.2624126 1448.43314 1413.778823 1.024946672 1.132175317 0.895943649 0.930297775 1.004654142 0.758851444 0.665302222 0.420336196 1.024511838 1 10.46534072 -4.236723989 0.741973742 1.016072381 0.033615942 0.906984206 0.061750679 0.542018378 0.204409479 0.009863098 0.446373565 5.80E-05 4.236723989 -0.982456438 down SAS(ph)QSS(ph)LDKLDQELK ddPTM_HeLa_Curcumin_4h_R1 1 SASQSSLDKLDQELK 15 1 O60271-3;O60271;A0A087X2D8;O60271-5;O60271-9;O60271-4;O60271-2 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 2 0 S(0.05)AS(0.884)QS(0.287)S(0.78)LDKLDQELK 124.68 0.00050115 0 2855.1 2576 3008.9 2920.6 3135.6 3340.7 3115.8 2109.1 3004.9 2941.5 TRUE FALSE FALSE 2629.115822 2798.657962 3120.412481 2908.515331 3098.210018 2647.801163 3203.220962 2752.154881 2675.269988 3043.716906 0.863784611 0.919486946 1.025197999 0.955580108 1.017903476 0.869923598 1.052404366 0.90420856 0.878948362 1 11.57161847 YLLSQSS(ph)PAPLTAAEEELR ddPTM_HeLa_Curcumin_4h_R1 2 YLLSQSSPAPLTAAEEELR 19 0 F8VS81;Q12792-4;Q12792;Q12792-3 F8VS81 TWF1 Twinfilin-1 1 0 YLLSQS(0.042)S(0.958)PAPLTAAEEELR;YLLS(0.018)QS(0.3)S(0.567)PAPLT(0.115)AAEEELR ; 150.92 5.45E-05 61501700 4598.5 3147.96 3393.9 3747.2 3714.4 5600.3 5268.93 9835.83 3764.5 3275 TRUE FALSE FALSE 4234.523873 3420.055635 3519.68092 3731.695079 3670.108206 4438.734652 5416.761995 12834.72929 3351.543768 3388.806006 1.249562195 1.009221428 1.038619771 1.101182857 1.083009237 1.309822587 1.598427879 3.787389796 0.989004317 1 11.72656134 -4.115392897 1.852429714 1.107612576 5.44792545 0.98511328 0.09888926 0.121297748 0.307650226 0.016160939 1.027473758 7.67E-05 4.115392897 4.340312874 up SAS(ph)SGAEGDVSSEREP ddPTM_HeLa_Curcumin_4h_R1 2 SASSGAEGDVSSEREP 16 1 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 0 S(0.009)AS(0.496)S(0.496)GAEGDVSSEREP;S(0.004)AS(0.498)S(0.498)GAEGDVSSEREP ; 227.91 9.07E-21 254410000 5753.2 4263.7 4944.9 5169 4828 5808.2 4679.6 3154.2 6451.6 5206 TRUE FALSE FALSE 5297.828149 4632.235229 5128.162344 5147.612048 4770.429253 4603.513848 4810.896982 4115.90106 5743.875621 5386.908112 0.983463619 0.859906115 0.951967666 0.955578217 0.885559797 0.854574415 0.893072033 0.764056296 1.06626575 1 12.39524174 -1.03010736 0.195929384 1.015641069 3.66E-20 0.71822821 0.043840111 19.06693553 0.218813372 0.038447817 5.937808156 0.093302362 1.03010736 -1.015641069 SAS(ph)TDLGTADVVLGR ddPTM_HeLa_Curcumin_4h_R1 1 SASTDLGTADVVLGR 15 0 H7C0E9;A0A0U1RRA6;B5MCU0;B5MCG9;Q9Y2K5-3;Q9Y2K5-2;Q9Y2K5 H7C0E9 R3HDM2 R3H domain-containing protein 2 1 0 S(0.127)AS(0.436)T(0.436)DLGTADVVLGR 199.33 3.64E-07 7506000 1433.7 876.98 1005.7 1325.2 1116.4 4285 3884 1142.6 1268.7 1086.6 TRUE FALSE FALSE 1320.221132 952.7822435 1042.972127 1319.716674 1103.087659 3396.242698 3992.974587 1490.97348 1129.526784 1124.359269 1.174198647 0.847400177 0.927614647 1.173749983 0.981081127 3.020602748 3.551333365 1.326065005 1.004595964 1 10.13488738 -5.26608766 24.9859974 1.055266866 2.724533709 0.658773499 0.531580825 148.9944036 800894.7766 0.068388885 0.15779674 5.42E-06 5.26608766 1.669266844 SAS(ph)TEKLEQGTSALIR ddPTM_HeLa_Curcumin_4h_R1 1 SASTEKLEQGTSALIR 16 1 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 0 S(0.039)AS(0.803)T(0.153)EKLEQGT(0.003)S(0.001)ALIR 69.878 0.011064 17643000 2951.5 2417.8 2606 3219.8 2521.1 3452.3 2506.3 1335.5 3237.2 2688.3 TRUE FALSE FALSE 2717.885661 2626.783858 2702.580652 3206.477321 2491.037529 2736.254065 2576.620033 1742.687802 2882.087259 2781.718225 0.977052829 0.944302638 0.971550831 1.152696665 0.895503185 0.983656087 0.926269242 0.62647891 1.036081668 1 11.44176057 -4.171886742 2.11599268 0.989762589 0.466698061 0.749795556 0.063574769 0.320597017 1.287559172 0.008123157 0.344838701 6.73E-05 4.171886742 -0.523064528 SAS(ph)TSGVPPPSVTPLR ddPTM_HeLa_Curcumin_4h_R1 1 SASTSGVPPPSVTPLR 16 0 Q9P242;Q9P242-3 Q9P242 NYAP2 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 1 0 S(0.191)AS(0.4)T(0.4)S(0.009)GVPPPSVTPLR 173.19 7.51E-05 21344000 2259.2 1823 2010 2555.9 1750.6 2572.6 1860.3 1999.1 2224.3 1937.3 TRUE FALSE FALSE 2080.381936 1980.571997 2084.492368 2545.324363 1729.725238 2039.013761 1912.495011 2608.616387 1980.299855 2004.621031 1.037793131 0.988003202 1.039843609 1.269728454 0.862868947 1.017156724 0.954043174 1.301301516 0.987867445 1 10.96911381 -4.252760132 24.31935144 1.02088016 1.301301728 0.433450351 0.097276127 535.0371649 1499131.147 0.012331814 0.19148239 5.59E-05 4.252760132 0.280421567 SAS(ph)VNKEPVSLPGIMR ddPTM_HeLa_Curcumin_4h_R1 2 SASVNKEPVSLPGIMR 16 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 S(0.006)AS(0.994)VNKEPVSLPGIMR;S(0.036)AS(0.942)VNKEPVS(0.022)LPGIMR ; 210.2 7.37E-10 415350000 2614.3 1812.48 1764.35 2111.1 1883.13 2940.9 2897.9 2861.4 2368.7 2168.1 TRUE FALSE FALSE 2407.375396 1969.142695 1829.738363 2102.364828 1860.674905 2330.924189 2979.207275 3733.827688 2108.859536 2243.441314 1.073072597 0.877733098 0.815594485 0.937116035 0.829384256 1.038994947 1.327963097 1.664330449 0.94001101 1 11.13149773 -4.505571139 2.151686842 0.985251396 1.695775638 0.871842447 0.088847464 0.132483869 0.964351521 0.015313433 0.147806313 3.12E-05 4.505571139 0.710524242 SAS(ph)WGSADQLK ddPTM_HeLa_Curcumin_4h_R1 1 SASWGSADQLK 11 0 Q86VQ1;H7C0Q2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 0 S(0.01)AS(0.731)WGS(0.26)ADQLK 165.35 0.00026931 36330000 2828.9 2252.5 2839.8 2949.5 2731.9 2691.7 2508.8 1276.5 2206.4 2013 TRUE FALSE FALSE 2604.98958 2447.196063 2945.045486 2937.295751 2699.323877 2133.411078 2579.190176 1665.698974 1964.36344 2082.9516 1.250624153 1.174869384 1.413880901 1.410160347 1.295912913 1.024224988 1.238238169 0.799682035 0.943067251 1 11.0244136 -2.686590392 11.47622239 1.158428734 0.744768428 0 0.195155431 0 0 0.025629011 0 0.002057831 2.686590392 -0.413660306 SAS(ph)WGSADQLKEQIAK ddPTM_HeLa_Curcumin_4h_R1 1 SASWGSADQLKEQIAK 16 1 Q86VQ1;H7C0Q2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 0 S(0.009)AS(0.863)WGS(0.128)ADQLKEQIAK 124.09 0.0065492 18695000 1486.6 1273.6 1079.2 1377.9 1031.1 1489.7 1249.1 597.54 1081.5 1217.4 TRUE FALSE FALSE 1368.934041 1383.684309 1119.196101 1372.198615 1018.804806 1180.719428 1284.146384 779.7271953 962.8621558 1259.704559 1.086710397 1.098419704 0.888459197 1.089301936 0.808764879 0.937298685 1.019402823 0.618976243 0.764355538 1 10.2988697 -3.378725356 0.591427545 1.035367703 1.65E-23 0.243914649 0.132394696 5.315393384 0.596060417 0.017516473 4.785821518 0.000418095 3.378725356 -1.035367703 SAS(ph)WGSTDQLK ddPTM_HeLa_Curcumin_4h_R1 1 SASWGSTDQLK 11 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 0 S(0.048)AS(0.947)WGS(0.003)T(0.003)DQLK 140.45 0.0013477 29531000 3052.9 2363.1 2696.2 2898.5 3012 3192.3 2202.2 2065.1 2551.3 2745 TRUE FALSE FALSE 2811.259744 2567.355834 2796.123544 2886.506775 2976.083867 2530.180995 2263.987805 2694.739483 2271.428773 2840.388546 0.989744783 0.903874872 0.984415864 1.016236592 1.047773507 0.890786931 0.797069756 0.948722134 0.799689457 1 11.47187258 -5.122722464 5.927461711 0.991694488 0.866319145 0.132999875 0.07753933 0.11826489 5.228104536 0.006456726 0.01681536 7.54E-06 5.122722464 -0.125375343 SAS(ph)WGSTDQLKEIAK ddPTM_HeLa_Curcumin_4h_R1 1 SASWGSTDQLKEIAK 15 1 Q6P1L5 Q6P1L5 FAM117B Protein FAM117B 1 0 S(0.003)AS(0.994)WGS(0.002)T(0.001)DQLKEIAK 136.63 0.0057211 26955000 2632.6 1885.4 1816.8 1671.6 1565.6 2331.5 1266.2 1018.1 2085 1923.6 TRUE FALSE FALSE 2424.226932 2048.365575 1884.132206 1664.683362 1546.931243 1847.920619 1301.726164 1328.514003 1856.280716 1990.444957 1.217932163 1.029099332 0.94658845 0.836337301 0.777178609 0.92839574 0.653987522 0.667445738 0.932595855 1 10.95887526 -6.385956069 1.353422669 1.102804664 0.754701148 0.612305008 0.101459265 0.181784902 0.657982718 0.018405169 0.032936757 4.11E-07 6.385956069 -0.348103516 SASAPT(ph)LAETEKETAEHLDLAGASSRPK ddPTM_HeLa_Curcumin_4h_R1 2 SASAPTLAETEKETAEHLDLAGASSRPK 28 2 Q86W92-2 Q86W92-2 PPFIBP1 Liprin-beta-1 1 0 S(0.018)AS(0.05)APT(0.711)LAET(0.174)EKET(0.046)AEHLDLAGASSRPK;S(0.004)AS(0.042)APT(0.77)LAET(0.171)EKET(0.013)AEHLDLAGASSRPK ; 64.27 0.00048182 19140300 3045.6 2360.3 2170 2730 2940.4 3451.1 2220.7 1776.72 3856.9 2886 TRUE FALSE FALSE 2804.537546 2564.313815 2250.422109 2718.703983 2905.33765 2735.302958 2283.006865 2318.433749 3433.807719 2986.288285 0.939138247 0.858696003 0.753585017 0.91039569 0.972892559 0.915954086 0.764496474 0.776359657 1.149858082 1 11.54413773 -1 0.056974181 1.241636567 0.169820495 0.503922855 0.082215591 243.4586282 1.050502397 4.266366269 22.11250987 0.1 1 -1.071816072 SASDSGCDPASK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 SASDSGCDPASKK 13 1 Q7LBC6;H0Y9V5 Q7LBC6 KDM3B Lysine-specific demethylase 3B 0 1 ; SASDSGCDPASK(1)K;SASDSGCDPASK(1)K 257.54 4.64E-63 5278400 8409.8 8060.7 7078.7 6489.4 6172.2 9812.2 5167.6 3217.6 7726 7112.9 FALSE TRUE FALSE 7744.155456 8757.43099 7341.042849 6462.548582 6098.600546 7777.039114 5312.588948 4198.631428 6878.477129 7360.072746 1.052184635 1.189856581 0.997414442 0.878054987 0.828606015 1.056652479 0.721812016 0.570460588 0.93456646 1 12.84550431 -3.828482519 0.650099069 1.030184396 2.43E-13 0.653087906 0.100828777 2.147604707 0.425221631 0.016958868 1.865454563 0.000148429 3.828482519 -1.030184396 SASFS(ph)QGTR ddPTM_HeLa_Curcumin_4h_R1 1 SASFSQGTR 9 0 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 0 S(0.001)AS(0.287)FS(0.713)QGTR 119.53 0.0063573 40276000 1757.4 1371.5 1328.8 1394.3 1635.5 1571.2 1117.1 609.07 1597.8 1411.1 TRUE FALSE FALSE 1618.299936 1490.046349 1378.046497 1388.530756 1615.997731 1245.315409 1148.442819 794.7726392 1422.525337 1460.13562 1.108321661 1.020484898 0.943779796 0.950960128 1.106744955 0.852876536 0.78653161 0.54431426 0.974241925 1 10.51188666 -3.944990839 0.769876548 1.04280814 6.74E-18 0.835689035 0.064600378 1.053515441 0.321343568 0.01100593 1.055442135 0.000113503 3.944990839 -1.04280814 SASLISQAEHSLK ddPTM_HeLa_Curcumin_4h_R1 1 SASLISQAEHSLK 13 0 C9J453;A0A087X255;O15344-2;O15344 C9J453 MID1 E3 ubiquitin-protein ligase Midline-1 0 0 140.17 0.0084001 27057000 1953.8 1241.3 1433.5 1331 1665 2020.5 1528.5 1393.4 1471.1 1710.8 FALSE FALSE TRUE 1799.154668 1348.592441 1486.626771 1325.492675 1645.145962 1601.425524 1571.385596 1818.241246 1309.724011 1770.250173 1.016327916 0.761808959 0.839783435 0.748760088 0.929329644 0.904632322 0.88766301 1.027109769 0.739852497 1 10.78973754 -7.293428557 24.47784244 1.007710421 0.869516539 0 0.113544852 356.1459102 272518.872 0.012925414 0.014781494 5.09E-08 7.293428557 -0.138193882 SASLS(ph)HPGGEGEPAR ddPTM_HeLa_Curcumin_4h_R1 1 SASLSHPGGEGEPAR 15 0 C9JXU1;A6NN40;Q2M3G4-2;Q2M3G4 C9JXU1 SHROOM1 Protein Shroom1 1 0 S(0.006)AS(0.303)LS(0.691)HPGGEGEPAR 130.66 0.00071029 6193600 399.29 455.11 527.74 834.78 755.71 638.05 419.25 391.83 566.85 480.87 TRUE FALSE FALSE 367.6857752 494.4476805 547.2985086 831.3259015 746.6986518 505.7112377 431.0130266 511.2971632 504.6679732 497.5801967 0.738947767 0.9937045 1.099920198 1.670737515 1.500659907 1.016341167 0.866218209 1.027567348 1.014244491 1 8.958785258 -6.78966705 3.22129221 0.877553143 1.213742057 0.229384412 0.234184023 0.253589461 5.455376007 0.042725206 0.058995613 1.62E-07 6.78966705 0.336188914 SASNGSKT(ph)DT(ph)EEEEEQQQQQK ddPTM_HeLa_Curcumin_4h_R1 2 SASNGSKTDTEEEEEQQQQQK 21 1 Q9UGU0-2;Q9UGU0;A9JX13 Q9UGU0-2 TCF20 Transcription factor 20 2 0 SAS(0.001)NGS(0.165)KT(0.841)DT(0.993)EEEEEQQQQQK;S(0.002)AS(0.015)NGS(0.184)KT(0.815)DT(0.984)EEEEEQQQQQK ; 85.203 0.00051129 32020000 8506 7730.6 7417.8 7798 9236.6 10683 9151 4829.4 9879.1 8092.8 TRUE FALSE FALSE 7832.741125 8398.798617 7692.710193 7765.733942 9126.459578 8467.225378 9407.752431 6301.861828 8795.387446 8374.024198 0.935361654 1.002958484 0.918639595 0.927359864 1.0898535 1.011129796 1.12344462 0.752548796 1.050317892 1 13.03170537 SASNVPSGKS(ph)TDEEEEAQTPQAPR ddPTM_HeLa_Curcumin_4h_R1 1 SASNVPSGKSTDEEEEAQTPQAPR 24 1 Q9P2K3;Q9P2K3-3 Q9P2K3 RCOR3 REST corepressor 3 1 0 SAS(0.001)NVPS(0.096)GKS(0.84)T(0.062)DEEEEAQTPQAPR 106 1.71E-06 12220000 2054 1890.2 1957.6 1766.2 1686.4 2047.9 1704.6 1324.6 2158.4 1905.2 TRUE FALSE FALSE 1891.423733 2053.580465 2030.150378 1758.891932 1666.290781 1623.142455 1752.426488 1728.464442 1921.62892 1971.405558 0.959429035 1.041683411 1.029798445 0.892201975 0.845229828 0.823342741 0.888922364 0.876767561 0.974750686 1 10.94500888 -6.107257967 4.685630605 0.989018099 0.859207119 0.845430772 0.029053418 0.077110561 2.709360964 0.00497993 0.008435925 7.81E-07 6.107257967 -0.12981098 SASNVPSGKST(ph)DEEEEAQTPQAPR ddPTM_HeLa_Curcumin_4h_R1 2 SASNVPSGKSTDEEEEAQTPQAPR 24 1 Q9P2K3;Q9P2K3-3 Q9P2K3 RCOR3 REST corepressor 3 1 0 SASNVPS(0.056)GKS(0.236)T(0.704)DEEEEAQT(0.002)PQAPR;SASNVPS(0.022)GKS(0.162)T(0.816)DEEEEAQTPQAPR ; 102.61 0.00011952 6476500 1697.62 1252.37 1355.08 1550.2 1667.79 2243.1 1529.48 872.61 1692.28 1466.54 TRUE FALSE FALSE 1563.251586 1360.619282 1405.300457 1543.785683 1647.902694 1777.855775 1572.393092 1138.664772 1506.641118 1517.502156 1.030147852 0.896617693 0.926061588 1.017320257 1.085931039 1.171567215 1.0361719 0.750354632 0.992842819 1 10.56748285 SASPDDDLGS(ph)SNWEAADLGNEERK ddPTM_HeLa_Curcumin_4h_R1 1 SASPDDDLGSSNWEAADLGNEERK 24 1 E9PM92;O00193;E9PQA1 E9PM92 C11orf58;SMAP Small acidic protein 1 0 S(0.007)AS(0.11)PDDDLGS(0.704)S(0.179)NWEAADLGNEERK 116.27 3.41E-07 22693000 2455 1925.9 2137.6 2397.1 1977.2 2360.2 1800.1 1600.1 2781.2 2503.4 TRUE FALSE FALSE 2260.684159 2092.366214 2216.821336 2387.181435 1953.623181 1870.667915 1850.605961 2087.963124 2476.109318 2590.392964 0.872718615 0.80774085 0.855785731 0.921551853 0.754180238 0.722156036 0.714411283 0.806041073 0.955881734 1 11.33895526 -8.101482692 0.102808791 1.254266479 0.543328105 0.688727302 0.051801326 5.300933327 0.312356289 1.204075922 0.868776709 7.92E-09 8.101482692 -0.710938373 SASQS(ph)S(ph)LDKLDQELKEQQK ddPTM_HeLa_Curcumin_4h_R1 1 SASQSSLDKLDQELKEQQK 19 2 O60271-3;O60271;A0A087X2D8;O60271-5;O60271-9;O60271-4;O60271-2 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 2 0 S(0.028)AS(0.18)QS(0.9)S(0.892)LDKLDQELKEQQK 61.524 0.014923 53596000 3310.3 2537.3 2656.8 2702.3 2516.9 3149.5 2309.6 1708.1 3235.7 2734.6 TRUE FALSE FALSE 3048.286262 2756.612906 2755.263345 2691.118599 2486.887611 2496.258198 2374.40116 2228.891827 2880.751805 2829.627146 1.077274886 0.974196515 0.973719576 0.951050601 0.878874665 0.882186263 0.839121565 0.787698065 1.018067631 1 11.46639625 -5.743111659 0.728938949 1.035314609 0.803378956 0.890756952 0.027925821 0.219956924 0.204993151 0.006936602 0.028065533 1.81E-06 5.743111659 -0.231935653 SASQS(ph)SLDKLDQELK ddPTM_HeLa_Curcumin_4h_R1 1 SASQSSLDKLDQELK 15 1 O60271-3;O60271;A0A087X2D8;O60271-5;O60271-9;O60271-4;O60271-2 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 SASQS(0.934)S(0.066)LDKLDQELK 319.8 1.29E-107 15055000 3559.1 2942.8 3121 2978.8 3903.9 3431.1 2535.3 1679.8 2551.9 2259.7 TRUE FALSE FALSE 3277.393479 3197.162519 3236.667006 2966.474515 3857.348542 2719.451184 2606.433695 2191.963287 2271.962955 2338.224407 1.401659084 1.367346312 1.384241391 1.268686832 1.649691335 1.163041142 1.114706393 0.937447783 0.971661637 1 11.19119768 -2.967146229 8.874058201 1.231765047 1.225517176 0 0.217471395 0 0 0.030545518 0 0.001078583 2.967146229 -0.006247871 SASQS(ph)SLDKLDQELKEQQK ddPTM_HeLa_Curcumin_4h_R1 3 SASQSSLDKLDQELKEQQK 19 2 O60271-3;O60271;A0A087X2D8;O60271-5;O60271-9;O60271-4;O60271-2 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 SAS(0.004)QS(0.498)S(0.498)LDKLDQELKEQQK;S(0.001)AS(0.025)QS(0.487)S(0.487)LDKLDQELKEQQK;S(0.001)AS(0.024)QS(0.487)S(0.487)LDKLDQELKEQQK ;; 145.73 9.39E-05 132944000 11969 9230.3 10467.1 10936.2 9628.1 13347.1 9275.2 6053.6 11860.2 10369.5 TRUE FALSE FALSE 11021.64102 10028.126 10855.01993 10890.9489 9513.291196 10578.76101 9535.437149 7899.314773 10559.16573 10729.83935 1.027195344 0.934601691 1.011666585 1.015015094 0.886620096 0.985919794 0.888684055 0.736200656 0.984093553 1 13.38934086 -3.276513399 0.649307943 1.006378936 4.99E-20 0.766131847 0.04119838 2.962058985 0.338559253 0.00674074 2.983061145 0.000529038 3.276513399 -1.006378936 SASQSS(ph)LDKLDQELK ddPTM_HeLa_Curcumin_4h_R1 1 SASQSSLDKLDQELK 15 1 O60271-3;O60271;A0A087X2D8;O60271-5;O60271-9;O60271-4;O60271-2 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 SASQS(0.414)S(0.586)LDKLDQELK 151.11 0.0041396 16472000 2796.8 2300.1 3095.2 2745.9 3479.3 3529 2476.1 1294.8 2792.5 2413.1 TRUE FALSE FALSE 2575.430329 2498.910395 3209.910835 2734.538193 3437.81162 2797.04562 2545.572702 1689.578559 2486.169736 2496.955045 1.031428393 1.000783094 1.285530086 1.095149149 1.376801567 1.12018261 1.019470778 0.676655578 0.995680616 1 11.28595413 -4.270549659 3.72961448 1.070729535 0.638621722 0.494638196 0.126518042 0.18974934 4.973583981 0.01903184 0.222522099 5.36E-05 4.270549659 -0.432107813 SASQSS(ph)LDKLDQELKEQQK ddPTM_HeLa_Curcumin_4h_R1 1 SASQSSLDKLDQELKEQQK 19 2 O60271-3;O60271;A0A087X2D8;O60271-5;O60271-9;O60271-4;O60271-2 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 SAS(0.003)QS(0.232)S(0.764)LDKLDQELKEQQK 132.67 0.0001229 27476000 1352.4 965.91 937.7 1111.5 786.56 863.11 924.31 379.38 926.59 711.76 TRUE FALSE FALSE 1245.356113 1049.398956 972.4519869 1106.900908 777.1807857 684.0912567 950.2436509 495.0512155 824.9453952 736.493607 1.690925897 1.424858202 1.320380758 1.50293349 1.055244442 0.928848873 1.290226611 0.672173133 1.120098515 1 9.524529192 -5.648585477 6.247856089 1.352232958 0.996453869 0.371888769 0.227697551 0.231033068 11.85272784 0.041883972 0.084295633 2.25E-06 5.648585477 -0.355779089 TLLTGDGGGEAT(ph)GSPLAQGK ddPTM_HeLa_Curcumin_4h_R1 1 TLLTGDGGGEATGSPLAQGK 20 0 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;H0Y7E2 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 TLLTGDGGGEAT(0.789)GS(0.211)PLAQGK 279.5 1.23E-68 33639000 2635.6 2043.2 2045.3 2092.6 2151.6 3400.3 3566.5 4225.6 1780.1 1555.4 TRUE FALSE FALSE 2426.989479 2219.805104 2121.100617 2083.941376 2125.943575 2695.039451 3666.566391 5513.965988 1584.827484 1609.450034 1.507961992 1.379232071 1.317903987 1.294815826 1.320913063 1.674509549 2.27814863 3.425993893 0.984701264 1 10.65235207 -4.111259453 1.030019334 1.259876048 5.09504999 0.953450721 0.150141421 0.430559954 0.290705243 0.029375109 1.944996457 7.74E-05 4.111259453 3.835173942 up SASS(ph)SWLEGTSTQAK ddPTM_HeLa_Curcumin_4h_R1 1 SASSSWLEGTSTQAK 15 0 Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4;K7EL81;Q9BZL4-3 Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 0 SAS(0.054)S(0.764)S(0.182)WLEGTSTQAK 288.96 2.22E-77 16166000 2562 1842.5 2427.9 2265.2 2483.7 4015.7 3242.6 2095.9 3071.5 2782 TRUE FALSE FALSE 2359.214997 2001.75749 2517.88011 2255.827203 2454.0835 3182.798554 3333.578629 2734.930262 2734.564135 2878.674293 0.819549125 0.695374775 0.874666549 0.783634053 0.852504747 1.105647333 1.158025636 0.950065893 0.949938707 1 11.49118885 -5.261250998 24.861171 0.879309614 1.079924231 0.511105283 0.095119164 12.13590629 1601412.395 0.016022462 0.038184012 5.48E-06 5.261250998 0.200614617 SASSASSLFS(ph)PSSTLFSSSR ddPTM_HeLa_Curcumin_4h_R1 2 SASSASSLFSPSSTLFSSSR 20 0 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;H0YEH2;E9PR38;Q14671-4;H0YDK8 Q5T1Z4 PUM1 Pumilio homolog 1 1 0 SASSASS(0.001)LFS(0.997)PS(0.003)STLFSSSR;SASSASSLFS(0.997)PS(0.003)STLFSSSR ; 259.55 2.88E-44 105837000 3218.2 3026.6 3068.4 2798.2 2640 5401.6 4381.9 1884.67 3371.5 2146.1 TRUE FALSE FALSE 2963.476074 3288.205818 3182.117603 2786.62179 2608.519724 4281.247271 4504.844321 2459.297207 3001.654885 2220.676815 1.334492284 1.480722361 1.432949442 1.254852471 1.174650767 1.927901999 2.028590694 1.107453903 1.351684705 1 11.11678373 -8.869799952 0.138666793 0.502031809 1.860238818 0.113093815 0.298493434 11.31110852 0.5522865 3.794165668 1.592440174 1.35E-09 8.869799952 1.358207009 SASSGAEGDVSS(ph)EREP ddPTM_HeLa_Curcumin_4h_R1 2 SASSGAEGDVSSEREP 16 1 Q8TEA8 Q8TEA8 DTD1 D-tyrosyl-tRNA(Tyr) deacylase 1 1 0 SASSGAEGDVS(0.031)S(0.969)EREP;SASSGAEGDVS(0.03)S(0.97)EREP ; 192.4 3.19E-06 46827000 6748.8 5527.4 5712.6 6989.7 6301.1 8999.9 6707.1 5369.4 7023.8 6074.4 TRUE FALSE FALSE 6214.625359 6005.163826 5924.313981 6960.778473 6225.963498 7133.21929 6895.283175 7006.505342 6253.306713 6285.484948 0.988726472 0.955401831 0.942538886 1.107436981 0.990530333 1.134871748 1.097016894 1.114711975 0.994880549 1 12.61780834 -5.587125019 1.161043341 0.989443112 1.116123449 0.60717899 0.043060723 0.25045866 0.645489342 0.006460093 0.021355224 2.59E-06 5.587125019 0.126680336 SASSS(ph)AAGSPGGLTSLQQQK ddPTM_HeLa_Curcumin_4h_R1 1 SASSSAAGSPGGLTSLQQQK 20 0 E5RJ10;E5RHB8;E5RJX6;E5RG91;Q8NEZ2-3;Q8NEZ2-2;Q8NEZ2 E5RJ10 VPS37A Vacuolar protein sorting-associated protein 37A 1 0 S(0.001)AS(0.003)S(0.062)S(0.72)AAGS(0.214)PGGLTSLQQQK 300.2 3.86E-162 0 1198.3 995.7 722.86 1079.2 1385.1 1930.6 1681.1 989.66 1305.9 706.8 TRUE FALSE FALSE 1103.453291 1081.763871 749.6498275 1074.734556 1368.583587 1530.171798 1728.267142 1291.402778 1162.646037 731.3612474 1.508766419 1.479110187 1.02500622 1.469498911 1.871282614 2.092224333 2.363082742 1.765752264 1.589701452 1 9.514440374 -3.29340204 0.176295628 0.946234311 3.789074679 0.447638174 0.30222606 12.71949918 0.282910718 0.461631427 8.428878783 0.00050886 3.29340204 2.842840367 SASSS(ph)WLEGTSTQAK ddPTM_HeLa_Curcumin_4h_R1 1 SASSSWLEGTSTQAK 15 0 Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4;K7EL81;Q9BZL4-3 Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 0 SAS(0.012)S(0.107)S(0.88)WLEGTSTQAK 110.44 0.0021837 6290400 1493.8 1264.2 1156.5 1484.7 1371.9 1999.4 1941.5 991.74 1756.6 1538.5 TRUE FALSE FALSE 1375.564154 1373.471815 1199.360907 1478.556705 1355.540989 1584.701902 1995.973265 1294.116961 1563.905375 1591.96276 0.864068047 0.862753733 0.753385027 0.928763374 0.851490388 0.995439053 1.253781379 0.812906553 0.982375602 1 10.63659087 -5.005976172 24.90887893 0.909893218 1.056160507 0.184001298 0.120076345 296.7374992 1236833.536 0.016264181 0.046619285 9.86E-06 5.005976172 0.14626729 SASSSAAGS(ph)PGGLTSLQQQK ddPTM_HeLa_Curcumin_4h_R1 1 SASSSAAGSPGGLTSLQQQK 20 0 E5RJ10;E5RHB8;E5RJX6;E5RG91;Q8NEZ2-3;Q8NEZ2-2;Q8NEZ2 E5RJ10 VPS37A Vacuolar protein sorting-associated protein 37A 1 0 SASSS(0.133)AAGS(0.866)PGGLTSLQQQK 308.42 3.46E-99 8237700 2250.7 1850.4 1783.7 2021 1976.3 3587.1 3271.5 1686.9 2009.7 1374.7 TRUE FALSE FALSE 2072.55472 2010.340331 1849.805491 2012.637637 1952.733913 2843.095025 3363.289485 2201.228044 1789.240938 1422.470723 1.457010459 1.413273608 1.300417268 1.41488862 1.372776172 1.998701963 2.364399795 1.547468084 1.257840256 1 10.47418324 -1 0.121765503 0.818856464 4.682330711 0.496269657 0.263447347 48.94175267 0.408512903 1.122035652 32.26917307 0.1 1 3.863474248 RPLLLGS(ph)T(ph)S(ph)FIPIGRR ddPTM_HeLa_Curcumin_4h_R1 1 RPLLLGSTSFIPIGRR 16 2 C9JM78;C9JQ90;A0A0G2JRX6;Q02338;C9JB83;C9JEB9 C9JM78 BDH1 "D-beta-hydroxybutyrate dehydrogenase, mitochondrial" 3 0 RPLLLGS(1)T(1)S(1)FIPIGRR 73.841 0.020006 5189700 2081.6 1631.8 1525.6 1876.7 1887.3 1782.2 1312.8 488.4 2311.3 1891.3 TRUE FALSE FALSE 1916.839164 1772.845521 1582.140078 1868.934713 1864.79518 1412.55163 1349.633635 637.3109117 2057.756173 1957.022534 0.979467088 0.905889171 0.808442443 0.954988857 0.952873637 0.721786084 0.689636226 0.325653333 1.051472907 1 10.93444465 -4.23571413 0.791114745 0.973384551 7.02E-24 0.880194145 0.071120938 0.591042937 0.256731636 0.011210122 0.510223044 5.81E-05 4.23571413 -0.973384551 down LLSSNEDDANILSS(ph)PTDR ddPTM_HeLa_Curcumin_4h_R1 2 LLSSNEDDANILSSPTDR 18 0 H0YEG1;F5GY88;A0A0B4J1W0;O75448-2;O75448 H0YEG1 MED24 Mediator of RNA polymerase II transcription subunit 24 1 0 LLSSNEDDANILS(0.232)S(0.767)PTDR;LLSSNEDDANILS(0.03)S(0.97)PTDR ; 235.02 3.94E-24 95414000 6292.7 5325.5 4971 5658.7 5354.9 6582.3 4299 1319.86 6466.1 6014.9 TRUE FALSE FALSE 5794.626155 5785.81249 5155.229633 5635.285799 5291.046315 5217.056782 4419.61837 1722.279238 5756.785007 6223.917327 0.931025566 0.92960947 0.828293398 0.905424269 0.850115134 0.838227198 0.710102358 0.276719492 0.92494561 1 12.60360718 -4.235339256 1.165097644 0.94413522 4.61E-33 0.925076128 0.053609596 0.347286884 0.366556924 0.009422225 0.403509733 5.82E-05 4.235339256 -0.94413522 down SS(ph)PVGGGPR ddPTM_HeLa_Curcumin_4h_R1 1 SSPVGGGPR 9 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 0 S(0.224)S(0.776)PVGGGPR 139.38 0.0024445 286650000 2869.3 2740.3 2672.4 2443.1 2474.9 2897.8 2095.4 433.89 2207.2 2272.7 TRUE FALSE FALSE 2642.191877 2977.159321 2771.441495 2432.9911 2445.388434 2296.763615 2154.191285 566.1810636 1965.075682 2351.676156 1.123535599 1.265973342 1.178496235 1.034577441 1.039849142 0.976649616 0.916023781 0.240756391 0.835606415 1 11.19947369 -4.234331636 2.063668115 1.076885473 8.04E-19 0.826198751 0.111602112 0.194957017 0.845120028 0.01348616 0.400731738 5.83E-05 4.234331636 -1.076885473 down SAT(ph)PT(ph)PT(ph)VIARAGAQPS(ph)ANS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SATPTPTVIARAGAQPSANSK 21 1 A0A087WUJ4;Q92618 A0A087WUJ4 ZNF516 Zinc finger protein 516 5 0 S(0.667)AT(0.927)PT(0.703)PT(0.703)VIARAGAQPS(1)ANS(1)K 44.587 0.0085247 0 1433 1693.2 1491.8 1479 1521.1 1221.5 1162.3 1101.3 1209.9 2185.4 TRUE FALSE FALSE 1319.576538 1839.552663 1547.08742 1472.88029 1502.961876 968.1471309 1194.91101 1437.0813 1077.176997 2261.342487 0.583536791 0.813478132 0.684145559 0.651330039 0.664632573 0.428129368 0.5284078 0.635499182 0.476344032 1 11.14296379 -13.52287875 0.211196862 2.954535168 0.549441775 0 0.188341147 19.92790649 0.24812875 16.06871656 0.085946072 3.00E-14 13.52287875 -2.405093394 LGASEAAAFDS(ph)DESEAVGATR ddPTM_HeLa_Curcumin_4h_R1 4 LGASEAAAFDSDESEAVGATR 21 0 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2 H0YBE8 WWC1 Protein KIBRA 1 0 LGASEAAAFDS(0.999)DES(0.001)EAVGATR;LGASEAAAFDS(0.993)DES(0.007)EAVGATR;LGASEAAAFDS(0.737)DES(0.263)EAVGATR;LGASEAAAFDS(1)DESEAVGATR ;;; 267.93 1.21E-59 98380000 9601.5 9141 9062 8701.4 8444.3 9897.15 6251.19 2177.95 9315.3 8310.83 TRUE FALSE FALSE 8841.531144 9931.107308 9397.845692 8665.395912 8343.607238 7844.369526 6426.581567 2841.996929 8293.434896 8599.630724 1.028129164 1.154829507 1.09281968 1.007647443 0.970228549 0.912175159 0.747309015 0.33047895 0.964394305 1 13.070059 -4.234171841 1.202993141 1.029163464 2.67E-17 0.942478539 0.053235632 0.26878625 0.305449311 0.008226493 0.349650314 5.83E-05 4.234171841 -1.029163464 down SATDGNTS(ph)TTPPTSAK ddPTM_HeLa_Curcumin_4h_R1 1 SATDGNTSTTPPTSAK 16 0 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 0 SAT(0.005)DGNT(0.108)S(0.404)T(0.404)T(0.078)PPT(0.001)SAK 107.35 0.0018283 80286000 2348.5 1895.9 1786.9 2417.2 2358.5 2413.7 1829.4 1842.7 2452.3 2556.7 TRUE FALSE FALSE 2162.613747 2059.773148 1853.124086 2407.198267 2330.376428 1913.071412 1880.72804 2404.530747 2183.288825 2645.545135 0.817454867 0.778581745 0.700469654 0.909906331 0.880868142 0.72312938 0.710903782 0.908898025 0.825269921 1 11.36934932 -8.94783828 0.675474394 1.008111898 0.797845954 0.06505917 0.091273799 0.517872696 0.418881484 0.05967975 0.016769179 1.13E-09 8.94783828 -0.210265944 SATDGNTST(ph)TPPTSAKK ddPTM_HeLa_Curcumin_4h_R1 1 SATDGNTSTTPPTSAKK 17 1 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 0 SATDGNT(0.008)S(0.144)T(0.821)T(0.017)PPT(0.006)S(0.004)AKK 108.13 0.00068105 14869000 4111.3 3386.3 3273.9 3525.3 3363.8 4214.4 3080.3 2878.7 4626.4 4286.7 TRUE FALSE FALSE 3785.886267 3678.996683 3395.233614 3510.713243 3323.688882 3340.285934 3166.724928 3756.402378 4118.895495 4435.662506 0.853510893 0.829413121 0.765440024 0.791474382 0.749310588 0.753052318 0.713923777 0.846863884 0.928586314 1 12.11493388 -8.202480444 0.432349234 1.01393444 0.75325741 0.773277449 0.039993016 0.259191635 0.112458265 0.028448344 0.013622528 6.27E-09 8.202480444 -0.26067703 SATDGNTSTT(ph)PPTS(ph)AK ddPTM_HeLa_Curcumin_4h_R1 1 SATDGNTSTTPPTSAK 16 0 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 2 0 SATDGNT(0.019)S(0.19)T(0.371)T(0.42)PPT(0.233)S(0.767)AK 99.747 0.013391 32116000 3079.5 2854.8 3054.7 3021.3 3263.8 4471.8 3694.6 1854.2 3790.3 3525 TRUE FALSE FALSE 2835.754326 3101.556191 3167.909869 3008.798661 3224.881317 3544.298272 3798.260532 2419.537044 3374.513573 3647.493488 0.777452882 0.850325354 0.868516936 0.824894869 0.884136278 0.97170791 1.041334425 0.663342389 0.925159588 1 11.83268969 -9.570920594 1.369381527 0.999514804 0.857424938 0.13205778 0.098769202 0.517959487 1.750567856 0.067018887 0.015942061 2.69E-10 9.570920594 -0.142089866 SATDGNTSTT(ph)PPTSAK ddPTM_HeLa_Curcumin_4h_R1 2 SATDGNTSTTPPTSAK 16 0 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 0 SATDGNT(0.001)S(0.008)T(0.012)T(0.942)PPT(0.038)SAK;SATDGNTS(0.004)T(0.043)T(0.935)PPT(0.013)S(0.004)AK ; 170 4.69E-11 110590000 8657.8 7434.2 9421.2 8349.7 8216.8 9097.5 7423.5 7677.8 9341.9 8900.9 TRUE FALSE FALSE 7972.525994 8076.779122 9770.35796 8315.151154 8118.820027 7210.57595 7631.783431 10018.72588 8317.116942 9210.205612 0.865618677 0.876937982 1.060818658 0.902819275 0.881502582 0.782889791 0.828622482 1.087785257 0.903032711 1 13.16901765 -6.012020227 23.80621352 0.93989091 0.883639628 0.050518049 0.091614413 693.1714536 1372842.245 0.014307937 0.024611684 9.73E-07 6.012020227 -0.056251282 SATDGNTSTT(ph)PPTSAKK ddPTM_HeLa_Curcumin_4h_R1 1 SATDGNTSTTPPTSAKK 17 1 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 1 0 SATDGNTS(0.048)T(0.232)T(0.717)PPT(0.002)SAKK 94.911 0.0016449 15953000 3962.6 3204.2 2744.7 3828.1 2833.9 4117.7 2978.9 2534.1 4009.4 3742.5 TRUE FALSE FALSE 3648.956029 3481.15677 2846.420996 3812.260337 2800.107593 3263.642604 3062.479917 3306.735424 3569.578851 3872.551596 0.942261436 0.898931024 0.73502468 0.984431128 0.723065277 0.842762846 0.790817073 0.853890605 0.921764052 1 11.91906875 -7.288757446 1.053857445 0.983406713 0.820237681 0.375238523 0.073218193 0.259814855 0.566601692 0.013950676 0.016362702 5.14E-08 7.288757446 -0.163169032 ATVTPSPVK(ac)GK ddPTM_HeLa_Curcumin_4h_R1 2 ATVTPSPVKGK 11 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 0 1 ; ATVTPSPVK(1)GK;ATVTPSPVK(1)GK 155.06 2.28E-07 5868800 4939.2 3570.6 4902.7 4576 4908.9 6082.9 5030.4 7201.7 4700.6 3973.8 FALSE TRUE FALSE 4548.257108 3879.226754 5084.398375 4557.065724 4850.364574 4821.237972 5171.539485 9397.465177 4184.95594 4111.889254 1.106123445 0.943417129 1.236511506 1.108265676 1.179595138 1.17251163 1.257703981 2.285437325 1.017769614 1 12.00558569 -2.03933419 1.125436564 1.067002026 199.995298 0.941704806 0.088080211 40.73039894 0.4064084 0.01351551 20522.6384 0.009134101 2.03933419 198.928296 SATDGNTSTTPPTSAK(ac)KR ddPTM_HeLa_Curcumin_4h_R1 2 SATDGNTSTTPPTSAKKR 18 2 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 0 1 ; SATDGNTSTTPPTSAK(0.766)K(0.234)R;SATDGNTSTTPPTSAK(0.947)K(0.053)R 157.83 1.87E-05 5921500 2780.8 2038.04 2196.1 1826.61 2015.63 3266.3 2694.1 2765.7 2866 2467.2 FALSE TRUE FALSE 2560.696746 2214.199096 2277.489398 1819.051972 1991.594929 2588.832561 2769.689195 3608.949198 2551.60697 2552.935016 1.003040316 0.867315103 0.892106295 0.712533598 0.780119712 1.014061284 1.084903915 1.413647106 0.999479796 1 11.3179411 -4.274766433 1.924605375 0.94792471 1.546793399 0.68635746 0.10224815 0.425072077 1.659089825 0.017268772 0.447484554 5.31E-05 4.274766433 0.598868689 SATPEPVTDNRDVEDMELS(ph)DVEDDGSK ddPTM_HeLa_Curcumin_4h_R1 4 SATPEPVTDNRDVEDMELSDVEDDGSK 27 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 SATPEPVT(0.008)DNRDVEDMELS(0.991)DVEDDGS(0.001)K;SATPEPVT(0.004)DNRDVEDMELS(0.994)DVEDDGS(0.001)K;SATPEPVTDNRDVEDMELS(0.99)DVEDDGS(0.01)K;SATPEPVT(0.001)DNRDVEDMELS(0.993)DVEDDGS(0.007)K ;;; 85.366 1.42E-05 70242200 5832.8 5480.2 5451.6 6907.5 8004.7 10059 7047.9 7212.4 5457 5285.88 TRUE FALSE FALSE 5371.127725 5953.884069 5653.641092 6878.918595 7909.249181 7972.650012 7245.645106 9411.427558 4858.380753 5469.563937 0.982002914 1.088548217 1.033654814 1.257672216 1.446047486 1.457639056 1.324720799 1.720690656 0.88825742 1 12.4172101 -6.001602045 1.154835228 0.992646298 1.508441179 0.845937017 0.099122705 0.115308454 0.304049176 0.014287392 0.033819427 9.96E-07 6.001602045 0.51579488 VSGTLDTPEKT(ph)VDSQGPTPVCTPTFLER ddPTM_HeLa_Curcumin_4h_R1 2 VSGTLDTPEKTVDSQGPTPVCTPTFLER 28 1 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 0 VSGTLDT(0.046)PEKT(0.95)VDS(0.004)QGPTPVCTPTFLER;VSGTLDT(0.017)PEKT(0.561)VDS(0.364)QGPT(0.057)PVCT(0.001)PTFLER ; 116.55 1.02E-10 183018000 3377.4 2569.4 2739.1 2770.3 2461.03 3372.4 1912.42 751.52 3045.8 2722.3 TRUE FALSE FALSE 3110.075226 2791.487487 2840.613456 2758.837233 2431.683825 2672.926225 1966.077358 980.6549884 2711.68336 2816.899722 1.104077366 0.990978651 1.00841838 0.979387804 0.863248274 0.948889378 0.69795788 0.348132729 0.962648169 1 11.45989249 -4.234168425 0.920522289 1.036009297 1.19E-26 0.915748953 0.0601966 0.429802579 0.262377252 0.009924648 0.450229933 5.83E-05 4.234168425 -1.036009297 down SATTTPSGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SATTTPSGSPR 11 0 Q2M2I8-2;Q2M2I8;A0A096LP60;A0A096LNZ0;A0A096LP25 Q2M2I8-2;A0A096LNZ0 AAK1 AP2-associated protein kinase 1 1 0 SATTTPS(0.004)GS(0.996)PR 108.98 0.0070885 1447500 696.73 651.51 698.17 663.42 530.23 726.54 567.15 431.26 770.62 763.14 TRUE FALSE FALSE 641.5830853 707.8236213 724.0447944 660.6749438 523.9073536 575.8474142 583.0627026 562.7491887 686.084914 789.6590582 0.812481132 0.896366114 0.91690811 0.836658476 0.663460196 0.729235495 0.738372715 0.712648304 0.868836882 1 9.625086082 -13.52287874 0.035277494 2.242185919 6.93E-12 0.556345649 0.067009043 356.4072544 1.00667606 52.21670876 19.34115939 3.00E-14 13.52287874 -2.242185919 SAVAVYSYSCEGPEEES(ph)EDDSHLEGR ddPTM_HeLa_Curcumin_4h_R1 2 SAVAVYSYSCEGPEEESEDDSHLEGR 26 0 A0A1B0GTI3;A0A1B0GTY1;A0A1B0GUC3;A0A1B0GV98;A0A1B0GTC5;A0A1B0GU26;A0A1B0GTC3;A0A1B0GVH5;Q9C0B1 A0A1B0GTI3 FTO Alpha-ketoglutarate-dependent dioxygenase FTO 1 0 SAVAVYSYSCEGPEEES(0.984)EDDS(0.016)HLEGR;SAVAVYSYSCEGPEEES(0.973)EDDS(0.027)HLEGR ; 199.29 1.18E-18 43594000 5320 4889.4 5289.9 4254.9 5668.3 5533.2 3911.7 4301.4 4821.5 3732.1 TRUE FALSE FALSE 4898.916386 5312.017949 5485.948347 4237.294351 5600.709225 4385.551948 4021.451774 5612.877059 4292.593513 3861.790197 1.268560988 1.375532506 1.420571307 1.097235773 1.450288322 1.135626672 1.041343928 1.453439149 1.111555339 1 11.91505407 -9.001434119 0.854101805 1.003447706 1.273028926 0.264053589 0.145129157 0.515445972 0.698975109 0.083820903 0.027332564 9.97E-10 9.001434119 0.269581221 SAVEDEGLK ddPTM_HeLa_Curcumin_4h_R1 2 SAVEDEGLK 9 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37 A0A0G2JIW1 HSPA1B;HSPA1A Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A 0 0 ; ; 161.92 1.73E-08 15671600 10994.7 8728 10141 10594.8 12016.4 11954.6 10675.6 9264.5 9329.2 8370.1 FALSE FALSE TRUE 10124.45789 9482.409429 10516.83438 10550.96152 11873.11228 9475.081204 10975.1286 12089.2034 8305.810101 8660.960352 1.168976359 1.094845034 1.214280398 1.21822074 1.370877108 1.093998912 1.267195341 1.395827127 0.958994126 1 13.08031129 -10.48587699 0.040558539 1.46E-10 2.020221748 0.665137347 0.079604677 150.5381915 0.969893108 31.94979293 17.94450864 3.27E-11 10.48587699 2.020221748 SAVENCQDSWR ddPTM_HeLa_Curcumin_4h_R1 1 SAVENCQDSWR 11 0 P52209-2;P52209 P52209-2 PGD "6-phosphogluconate dehydrogenase, decarboxylating" 0 0 169.99 1.07E-33 0 546.52 420.31 332.34 316.38 445.12 634.05 287.9 365.19 459.2 354.45 FALSE FALSE TRUE 503.2623653 456.6397235 344.6568128 315.0709034 439.8122347 502.5408828 295.9776992 476.5347499 408.8269089 366.7671111 1.372157835 1.245039999 0.939715701 0.859048955 1.199159416 1.370190695 0.80699084 1.299284302 1.114677125 1 8.518720465 -6.79107361 24.98536081 1.185849019 1.075388904 0.065602012 0.191683078 503.25832 424308.0259 0.034711736 0.045623819 1.62E-07 6.79107361 -0.110460114 SAVGFDYQGK ddPTM_HeLa_Curcumin_4h_R1 1 SAVGFDYQGK 10 0 Q14247;Q14247-3;Q14247-2 Q14247 CTTN Src substrate cortactin 0 0 140.16 6.73E-05 3189200 2195.3 1808.2 2006.7 2103 1844.9 1905.2 1863.1 1718 2401.4 1752.6 FALSE FALSE TRUE 2021.539689 1964.492751 2081.070067 2094.298343 1822.900772 1510.040044 1915.373572 2241.810291 2137.972428 1813.50272 1.114715554 1.083258784 1.147541741 1.154836064 1.005182266 0.832664891 1.056173532 1.236176967 1.178918788 1 10.82456319 -4.263063843 8.053969641 1.052071079 1.237567121 0.214332791 0.096808369 0.098183258 82.03290715 0.013201708 0.101557089 5.46E-05 4.263063843 0.185496042 SAVQKPPST(ph)GSAPAIESVD ddPTM_HeLa_Curcumin_4h_R1 1 SAVQKPPSTGSAPAIESVD 19 1 Q9NUQ3;Q9NUQ3-2 Q9NUQ3 TXLNG Gamma-taxilin 1 0 SAVQKPPS(0.363)T(0.469)GS(0.167)APAIES(0.001)VD 103.01 0.007236 4999900 2422.6 1640.9 2016.1 1919.9 1972.3 2526.9 1833.4 2540.6 2098.7 1625.4 TRUE FALSE FALSE 2230.848654 1782.732084 2090.81844 1911.955963 1948.781611 2002.792456 1884.84027 3315.217245 1868.477861 1681.882529 1.326399802 1.059962306 1.243141779 1.136795186 1.15869068 1.190804008 1.120672959 1.971134837 1.110944331 1 10.71586123 -4.259904732 24.96610091 1.156579846 1.97113511 0.889842393 0.086673575 41.10460319 668636.1933 0.01637117 0.138164056 5.50E-05 4.259904732 0.814555264 SAVRPAS(ph)LNLNR ddPTM_HeLa_Curcumin_4h_R1 1 SAVRPASLNLNR 12 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 S(0.053)AVRPAS(0.947)LNLNR 65.565 0.018813 17838000 1424.7 954.02 1426.7 1410.3 1159.3 1617 1542.2 723.11 1321 1366.3 TRUE FALSE FALSE 1311.933492 1036.481238 1479.574757 1404.464552 1145.476105 1281.615973 1585.469981 943.5829102 1176.089605 1413.778823 0.92796233 0.733128281 1.046539057 0.993411791 0.810222989 0.906518015 1.121441314 0.667419044 0.83187666 1 10.46534072 -8.600671821 1.011054866 0.992022698 0.909727861 0 0.140149834 1.028684564 2.129878785 0.045176914 0.024362271 2.51E-09 8.600671821 -0.082294837 SGS(ph)GISVISSTSVDQR ddPTM_HeLa_Curcumin_4h_R1 3 SGSGISVISSTSVDQR 16 0 Q15811;Q15811-3;F8W7U0;Q15811-7;Q15811-8;Q15811-9;Q15811-2;Q15811-4;Q15811-10;Q15811-11;Q15811-12;Q15811-6;Q15811-5;Q15811-13;A8CTZ0;C9JQZ7;D6PAW0 Q15811 ITSN1 Intersectin-1 1 0 S(0.044)GS(0.905)GIS(0.044)VIS(0.002)S(0.006)TSVDQR;S(0.011)GS(0.763)GIS(0.222)VISS(0.001)T(0.003)SVDQR;SGS(0.649)GIS(0.34)VIS(0.005)S(0.001)T(0.004)SVDQR ;; 244.18 2.68E-30 125710000 6348.3 5139.1 5430.4 5529.1 5800.9 6935.4 4485.2 1832.13 5984.7 5287.6 TRUE FALSE FALSE 5845.825356 5583.300905 5631.655401 5506.222049 5731.728056 5496.919862 4611.042641 2390.738003 5328.193383 5471.343706 1.068444183 1.020462468 1.029300242 1.006374731 1.047590567 1.004674566 0.842762379 0.436956282 0.97383635 1 12.41767947 -4.233767397 1.746611182 1.031256126 0.204874674 0.978119524 0.026389258 0.094435159 0.266075766 0.003843927 0.132013903 5.84E-05 4.233767397 -0.826381452 down SAYPPPAPAYALS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 SAYPPPAPAYALSSPR 16 0 O14497;O14497-2 O14497 ARID1A AT-rich interactive domain-containing protein 1A 1 0 SAYPPPAPAYALS(0.5)S(0.5)PR;SAYPPPAPAY(0.274)ALS(0.544)S(0.182)PR ; 102.63 0.0022257 25153000 2434.3 2325.2 2362.8 2774.2 1977.54 2999.9 2138.1 1714.97 2883.2 2236.7 TRUE FALSE FALSE 2241.622586 2526.179927 2450.367447 2762.721095 1953.959127 2377.686924 2198.089332 2237.856458 2566.920173 2314.425159 0.968543994 1.091493461 1.058736956 1.19369645 0.844252457 1.027333684 0.949734461 0.966916753 1.109096211 1 11.1764382 -4.750397565 24.3593399 1.004794826 0.958325583 0.019652282 0.092062802 439.6349451 969850.1609 0.011683957 0.042807239 1.78E-05 4.750397565 -0.046469243 SAYQEYDS(ph)DSDVPEELK ddPTM_HeLa_Curcumin_4h_R1 1 SAYQEYDSDSDVPEELK 17 0 H0Y7Q2;Q96JG6-3;Q96JG6 H0Y7Q2 CCDC132 Coiled-coil domain-containing protein 132 1 0 SAYQEYDS(0.939)DS(0.061)DVPEELK 186.74 4.19E-25 0 530.86 1322.1 918.13 764.24 649.4 716.46 894.1 795.1 620.07 1177.8 TRUE FALSE FALSE 488.8418708 1436.376433 952.1567055 761.0777774 641.6563291 567.8581198 919.1860397 1037.52233 552.0498723 1218.728462 0.401108111 1.178586106 0.781270591 0.62448511 0.526496549 0.465943102 0.754217258 0.851315418 0.452972003 1 10.25116101 -6.256470203 21.9983866 0.756320504 0.634112715 0.057803532 0.236233714 236.2594179 1045897.094 0.04189646 0.067927973 5.54E-07 6.256470203 -0.122207789 SAYQEYDS(ph)DSDVPEELKR ddPTM_HeLa_Curcumin_4h_R1 2 SAYQEYDSDSDVPEELKR 18 1 H0Y7Q2;Q96JG6-3;Q96JG6 H0Y7Q2 CCDC132 Coiled-coil domain-containing protein 132 1 0 SAYQEYDS(0.989)DS(0.011)DVPEELKR;SAY(0.001)QEY(0.02)DS(0.868)DS(0.11)DVPEELKR ; 125.11 0.00011703 89131000 7932.5 7324.7 7681.7 7335.6 8181.2 7791.3 6651.3 6942.4 6841 6617 TRUE FALSE FALSE 7304.634255 7957.81443 7966.39056 7305.247231 8083.644533 6175.296554 6837.917577 9059.105801 6090.559415 6846.940257 1.066846501 1.162243883 1.163496432 1.066936026 1.18062145 0.901906008 0.998682232 1.323088191 0.889530095 1 12.74124371 -8.189530455 1.108045762 1.012792554 1.102325492 0.202279961 0.114409621 0.706002274 1.800218945 0.029695021 0.021838983 6.46E-09 8.189530455 0.089532938 SCDELSPVS(ph)PTQGGYPSEPTR ddPTM_HeLa_Curcumin_4h_R1 1 SCDELSPVSPTQGGYPSEPTR 21 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 0 SCDELS(0.21)PVS(0.775)PT(0.016)QGGYPSEPTR 237.09 1.11E-30 19186000 1801.4 1278.5 1319.1 1341.9 1287.7 1458.8 1531.5 1479.2 1494.1 1328.4 TRUE FALSE FALSE 1658.817289 1389.007843 1367.987006 1336.347573 1272.345019 1156.228436 1574.469768 1930.201271 1330.200968 1374.561801 1.206797168 1.010509562 0.995216807 0.972198974 0.925636823 0.841161478 1.145433961 1.404230257 0.967727291 1 10.42475606 -4.331484235 3.790790084 1.049749867 1.418140922 0.558120367 0.102559244 0.167092052 4.100048518 0.017512568 0.146366515 4.66E-05 4.331484235 0.368391055 SCENLAPFNTALK ddPTM_HeLa_Curcumin_4h_R1 1 SCENLAPFNTALK 13 0 A8MU58;Q13155-2;Q13155 A8MU58 AIMP2 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 0 0 155.42 0.0001239 1291600 864.78 666.33 786.93 807.1 980.15 968.51 709.67 573.34 846.85 712.46 FALSE FALSE TRUE 796.3317505 723.9245961 816.0943181 803.7604341 968.4623514 767.6301086 729.5814302 748.1487267 753.9526737 737.217932 1.080184998 0.981968241 1.106991953 1.090261643 1.313671724 1.041252627 0.98964146 1.014827087 1.022699857 1 9.525947353 -9.135331747 0.510637999 0.986784604 1.084321151 0.082638809 0.088889495 2.816005203 1.08336436 0.135598717 0.024950526 7.32E-10 9.135331747 0.097536547 SCFES(ph)SPDPELK ddPTM_HeLa_Curcumin_4h_R1 1 SCFESSPDPELK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 SCFES(0.5)S(0.5)PDPELK 278.35 1.16E-58 3795500000 9795.2 8239.1 8119.7 8545.9 8669.3 9559.2 8382.8 5554.4 8891.9 7523.9 TRUE FALSE FALSE 9019.899584 8951.251091 8420.623225 8510.53933 8565.92426 7576.514166 8617.998807 7247.910991 7916.480816 7785.354965 1.158572682 1.149755038 1.081597854 1.093147245 1.100261234 0.973175173 1.106950016 0.930967313 1.01684263 1 12.9265471 -5.275128601 24.36092182 1.085636396 1.014022751 0.261642833 0.062438686 732.5318275 1303590.815 0.0104204 0.023428528 5.31E-06 5.275128601 -0.071613645 SCFESS(ph)PDPELK ddPTM_HeLa_Curcumin_4h_R1 2 SCFESSPDPELK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 SCFES(0.044)S(0.956)PDPELK;S(0.001)CFES(0.02)S(0.979)PDPELK ; 277.06 1.34E-58 404161000 17534.9 15476.7 15902.3 17240.3 17211.9 19641.8 15461.5 11603 17246.6 14387.1 TRUE FALSE FALSE 16146.99416 16814.43699 16491.65323 17168.96421 17006.65933 15567.86927 15895.30808 15140.70129 15354.69113 14887.05065 1.084633521 1.129467305 1.107785122 1.153281775 1.142379356 1.04573227 1.067727144 1.01703834 1.031412567 1 13.86177034 -8.796581195 0.838804732 1.003744657 1.095744484 0.351583765 0.041459855 0.442548692 0.608214936 0.022674483 0.009025667 1.60E-09 8.796581195 0.091999828 SCGTDSQSENEAS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 1 SCGTDSQSENEASPVK 16 0 H0Y398;C9JQ48;Q9H8U3 H0Y398 ZFAND3 AN1-type zinc finger protein 3 1 0 SCGTDSQSENEAS(1)PVK 247.5 1.05E-30 4890300 1189.5 1261.3 1427 1144.8 1085.6 1334.1 1024 1214.2 1116.8 1224.3 TRUE FALSE FALSE 1095.34982 1370.321152 1479.885875 1140.063121 1072.654929 1057.392622 1052.730684 1584.403991 994.2898341 1266.844334 0.864628582 1.081680768 1.168167103 0.899923606 0.846714076 0.834666575 0.830986614 1.250669832 0.784855572 1 10.30702355 -4.248403237 24.31221825 0.939681382 1.250670128 0.403928751 0.117761673 1187.463641 2214546.312 0.016049644 0.388317611 5.64E-05 4.248403237 0.310988747 SCLLEEEEES(ph)GEEAAEAME ddPTM_HeLa_Curcumin_4h_R1 1 SCLLEEEEESGEEAAEAME 19 0 Q969H6-2;Q969H6 Q969H6-2 POP5 Ribonuclease P/MRP protein subunit POP5 1 0 SCLLEEEEES(1)GEEAAEAME 78.69 0.004833 10214000 1985.3 1754.6 1590 1748.5 1617.1 1944.3 1250.1 757.48 2006.9 1854.8 TRUE FALSE FALSE 1828.16141 1906.259806 1648.926799 1741.26517 1597.817139 1541.030263 1285.174442 988.432165 1786.748091 1919.254162 0.952537421 0.993229476 0.859149784 0.907261375 0.832519825 0.802931834 0.669621808 0.515008478 0.930959602 1 10.90633006 -3.818645191 0.455314671 0.983347653 1.06E-18 0.941335768 0.035148146 0.862063339 0.090247371 0.00689975 0.497430143 0.000151829 3.818645191 -0.983347653 SCMVEES(ph)GTLESQLEAT(ph)KR ddPTM_HeLa_Curcumin_4h_R1 1 SCMVEESGTLESQLEATKR 19 1 A0A0D9SGF6 A0A0D9SGF6 SPTAN1 2 0 S(0.389)CMVEES(0.463)GT(0.147)LES(0.007)QLEAT(0.993)KR 43.532 0.019456 28630000 2186.5 1457 1899.2 1675.6 1956 3198.7 2076.8 1870.4 2149.2 1595.9 TRUE FALSE FALSE 2013.436218 1582.936588 1969.586023 1668.666811 1932.675978 2535.253563 2135.069419 2440.67635 1913.438137 1651.357406 1.219261324 0.958566923 1.192707294 1.010481925 1.170355957 1.535254303 1.292917821 1.477981896 1.158706244 1 10.68943668 -5.407407964 5.113207861 1.095300622 1.41895546 0.709399615 0.098739089 0.103175182 3.936422642 0.015227388 0.034627422 3.91E-06 5.407407964 0.323654838 T(ph)DGFAEAIHSPQVAGVPR ddPTM_HeLa_Curcumin_4h_R1 1 TDGFAEAIHSPQVAGVPR 18 0 P12270 P12270 TPR Nucleoprotein TPR 1 0 T(1)DGFAEAIHSPQVAGVPR 219.92 9.81E-17 43648000 1155.5 894.11 1184.4 948.65 1252 1737 2675 6412.8 1092.1 756.16 TRUE FALSE FALSE 1064.040956 971.3928843 1228.294906 944.7247377 1237.070718 1376.72662 2750.053301 8368.033199 972.2993623 782.4365037 1.359907099 1.241497399 1.569833335 1.207413935 1.58104934 1.75953782 3.514730317 10.69483998 1.242655931 1 9.611829869 -4.107379483 1.659150612 1.24018036 17.04905914 0.99461278 0.206070374 0.083456469 0.161307768 0.035094815 2.364230408 7.81E-05 4.107379483 15.80887878 up SCS(ph)FSSESR ddPTM_HeLa_Curcumin_4h_R1 2 SCSFSSESR 9 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 0 S(0.128)CS(0.444)FS(0.427)S(0.001)ESR;S(0.007)CS(0.636)FS(0.353)S(0.004)ESR ; 128.51 0.0041524 195632000 4837.5 3711.7 5147.5 5078.6 4988.1 6691.3 5197.9 5868.6 5328.5 4443.7 TRUE FALSE FALSE 4454.60677 4032.522809 5338.270878 5057.586099 4928.620165 5303.448954 5343.739085 7657.909124 4743.976881 4598.118244 0.968789086 0.876994152 1.160968595 1.099925193 1.071877647 1.153395514 1.162157822 1.665444149 1.031721376 1 12.16682785 -1 0.669873313 0.994234608 66.04480216 0.846655349 0.0791851 57.96885685 0.322308764 0.013067621 5626.261502 0.1 1 65.05056755 IADPEHDHTGFLTEY(ph)VATR ddPTM_HeLa_Curcumin_4h_R1 2 IADPEHDHTGFLTEYVATR 19 0 B3KR49;E9PJF0;E9PQW4;P27361-2;P27361-3;P27361 B3KR49 MAPK3 Mitogen-activated protein kinase;Mitogen-activated protein kinase 3 1 0 IADPEHDHTGFLT(0.006)EY(0.99)VAT(0.004)R;IADPEHDHT(0.006)GFLT(0.454)EY(0.481)VAT(0.059)R ; 216.77 1.14E-17 26180500 3571.1 3067.47 3444.8 3021.95 3192.47 6860.8 8145 12183.3 4017.8 3026.96 TRUE FALSE FALSE 3288.443667 3332.608438 3572.467318 3009.445972 3154.40188 5437.792743 8373.526779 15897.93208 3577.057392 3132.146635 1.049900931 1.064001411 1.140581121 0.960825377 1.007105429 1.736123297 2.673414675 5.075730462 1.142046593 1 11.61293604 -4.107062498 1.148009163 1.022456934 8.120900293 0.993610672 0.09890432 0.101056587 0.085896222 0.013722313 0.932937686 7.82E-05 4.107062498 7.098443359 up SCS(ph)PELQQK ddPTM_HeLa_Curcumin_4h_R1 1 SCSPELQQK 9 0 P16152 P16152 CBR1 Carbonyl reductase [NADPH] 1 1 0 S(0.032)CS(0.968)PELQQK 119.27 0.0064232 12357000 3326.2 2469.9 2953.7 2558.1 2605.7 3787.1 2603.1 2780 3045.1 2805.2 TRUE FALSE FALSE 3062.92776 2683.38715 3063.16672 2547.51526 2574.628729 3001.612771 2676.13598 3627.609202 2711.060148 2902.680491 1.055206651 0.924451437 1.055288975 0.877642327 0.886983165 1.034083076 0.921953342 1.249744577 0.933985038 1 11.50317006 -4.25037504 24.42844332 0.997889595 1.249744779 0.559101202 0.070638004 738.7926882 1631103.886 0.009842363 0.196377053 5.62E-05 4.25037504 0.251855184 NSPFQIPPPSPDS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 NSPFQIPPPSPDSK 14 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2;Q86W92-3 PPFIBP1 Liprin-beta-1 1 0 NSPFQIPPPS(0.377)PDS(0.622)K 91.657 0.0089571 12268000 5399.9 4528.8 4255.5 4484.1 4870.5 4769.6 3177.3 1189.9 5266.1 3947.1 TRUE FALSE FALSE 4972.492217 4920.249292 4413.212574 4465.545982 4812.422469 3780.331196 3266.446487 1552.695032 4688.422005 4084.261431 1.217476477 1.204685198 1.080541157 1.09335459 1.17828463 0.925585019 0.799764301 0.380165437 1.14792407 1 11.9958595 -4.232085771 1.159082939 1.115329116 1.61E-15 0.916768305 0.06994603 0.442462224 0.459302529 0.013963013 0.605742438 5.86E-05 4.232085771 -1.115329116 down SCSPELQQK ddPTM_HeLa_Curcumin_4h_R1 1 SCSPELQQK 9 0 P16152 P16152 CBR1 Carbonyl reductase [NADPH] 1 0 0 124.23 0.0010303 2254400 686.21 620.25 629.74 473.12 695.28 972.69 664.72 697.89 783.89 647.23 FALSE FALSE TRUE 631.8957544 673.8616462 653.0787184 471.1623548 686.9892401 770.9431295 683.3702542 910.6734483 697.8992282 669.7211943 0.943520617 1.006182352 0.975150143 0.70352015 1.025783932 1.151140409 1.020380212 1.359779944 1.042074275 1 9.387416815 -1.000008503 0.827985215 0.962085414 119.5836702 0.553705356 0.103861129 312.0129678 0.905974353 0.015771691 69634.66735 0.099998042 1.000008503 118.6215848 SCSSPAVSAVSQLPLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SCSSPAVSAVSQLPLSPK 18 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 0 SCSSPAVSAVSQLPLS(1)PK 187.56 8.86E-08 22772000 2286.6 1992.5 1862 1969 1802.2 1810.6 1102.1 952.51 2203 2286.2 TRUE FALSE FALSE 2105.613197 2164.722822 1931.007358 1960.8528 1780.709942 1435.06115 1133.02196 1242.925914 1961.336412 2365.64528 0.890079851 0.915066532 0.816270882 0.828887076 0.752737512 0.606625669 0.478948374 0.525406715 0.829091508 1 11.20801805 -4.768679664 0.387104657 0.973950504 0.206676704 0.867047268 0.059766159 0.629790428 0.084683108 0.013381718 0.209792888 1.70E-05 4.768679664 -0.7672738 TGS(ph)YGALAEITASK ddPTM_HeLa_Curcumin_4h_R1 3 TGSYGALAEITASK 14 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 T(0.243)GS(0.757)YGALAEITASK;T(0.031)GS(0.964)YGALAEIT(0.005)ASK;T(0.008)GS(0.99)YGALAEIT(0.002)ASK ;; 184.87 6.09E-05 228771000 11759.1 9780.6 10145 11191.2 11149.7 13363.7 9764.47 2543.43 12165.3 10915.3 TRUE FALSE FALSE 10828.35483 10625.99148 10520.98262 11144.89378 11016.74711 10591.91798 10038.43475 3318.910098 10830.79703 11294.60586 0.958719141 0.940802327 0.93150507 0.986744816 0.975398986 0.937785533 0.888781324 0.293849129 0.958935368 1 13.46334631 -4.232041812 2.862664005 0.971250798 0.145229214 0.986877605 0.022914493 0.043149472 0.46052471 0.003938412 0.085110649 5.86E-05 4.232041812 -0.826021584 down SCTPS(ph)PDQISHR ddPTM_HeLa_Curcumin_4h_R1 4 SCTPSPDQISHR 12 0 Q7Z2W4-2;Q7Z2W4;C9J6P4;Q7Z2W4-3 Q7Z2W4-2 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 0 S(0.003)CT(0.403)PS(0.594)PDQISHR;S(0.004)CT(0.334)PS(0.662)PDQISHR;SCTPS(1)PDQISHR;SCT(0.398)PS(0.602)PDQISHR ;;; 153.41 0.00018597 96107200 8010.2 8079.6 7502.1 8282.2 8805.4 8517.7 4624.27 3315.095 8648.7 7084.49 TRUE FALSE FALSE 7376.184218 8777.964622 7780.134426 8247.930451 8700.401356 6751.033006 4754.014571 4325.852205 7699.959248 7330.6755 1.006207984 1.197429162 1.061312075 1.12512557 1.186848518 0.920929184 0.648509755 0.590102809 1.050375132 1 12.83973043 -4.822597161 3.21449354 1.042855803 0.603021575 0.854249835 0.075311996 0.075952324 1.555974151 0.0122198 0.046777467 1.50E-05 4.822597161 -0.439834228 SCTPSPDQIS(ph)HRASLEDAPVDDLTR ddPTM_HeLa_Curcumin_4h_R1 1 SCTPSPDQISHRASLEDAPVDDLTR 25 1 Q7Z2W4-2;Q7Z2W4;C9J6P4;Q7Z2W4-3 Q7Z2W4-2 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 0 SCTPS(0.004)PDQIS(0.855)HRAS(0.141)LEDAPVDDLTR 111.25 6.53E-08 15349000 798.14 487.29 665.36 690.69 770.08 1098.6 795.16 644.01 782.82 644.85 TRUE FALSE FALSE 734.9663768 529.4091763 690.0188269 687.8321078 760.897299 870.7379762 817.4700495 840.3656843 696.9466045 667.2584895 1.101471751 0.793409428 1.034110225 1.030833056 1.140333635 1.304948517 1.225117496 1.259430487 1.044492675 1 9.382101946 -5.54660395 2.92572121 1.025419297 1.258794662 0.677479112 0.080410019 0.136643851 2.375577892 0.012738112 0.028933505 2.84E-06 5.54660395 0.233375364 SCTPSPDQISHRAS(ph)LEDAPVDDLTR ddPTM_HeLa_Curcumin_4h_R1 2 SCTPSPDQISHRASLEDAPVDDLTR 25 1 Q7Z2W4-2;Q7Z2W4;C9J6P4;Q7Z2W4-3 Q7Z2W4-2 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 0 SCTPSPDQIS(0.172)HRAS(0.828)LEDAPVDDLTR;SCT(0.001)PS(0.004)PDQIS(0.207)HRAS(0.788)LEDAPVDDLTR ; 97.366 3.96E-06 40976000 1514.45 1242.54 1114.07 1311.52 1379.39 2186.49 1728.27 1331.14 1432.98 1457.69 TRUE FALSE FALSE 1394.579684 1349.939621 1155.358414 1306.093278 1362.941675 1732.987327 1776.760605 1736.998458 1275.785679 1508.344619 0.924576298 0.894980898 0.765977748 0.865911716 0.90360098 1.148933278 1.177954018 1.151592571 0.845818431 1 10.55875037 -5.254133148 21.32854194 0.931935723 1.161339571 0.75302067 0.068335784 36.58492158 106795.4812 0.01119508 0.027776963 5.57E-06 5.254133148 0.229403848 SSS(ph)SSASPSSPSSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 S(0.012)S(0.001)S(0.965)S(0.002)S(0.019)ASPSSPSSR 162.67 0.00024687 9797400 2285.8 1751.8 1821.1 1830.2 1898.1 1975.1 1420.5 494.89 2100.4 1980.2 TRUE FALSE FALSE 2104.876518 1903.217786 1888.591568 1822.627117 1875.466397 1565.441996 1460.355407 645.7796828 1869.991375 2049.011803 1.027264223 0.928846668 0.921708487 0.889515187 0.915302877 0.763998526 0.712712052 0.315166405 0.912630846 1 11.00071258 -4.231757666 0.704393441 0.999822634 3.95E-26 0.904163878 0.060825413 0.524912013 0.175843855 0.009250876 0.420902611 5.86E-05 4.231757666 -0.999822634 down SDAEEDGGTVS(ph)QEEEDRKPK ddPTM_HeLa_Curcumin_4h_R1 2 SDAEEDGGTVSQEEEDRKPK 20 2 P27824-3;P27824;P27824-2 P27824-3 CANX Calnexin 1 0 SDAEEDGGT(0.01)VS(0.99)QEEEDRKPK;SDAEEDGGT(0.026)VS(0.974)QEEEDRKPK ; 66.041 0.0024088 78711000 6879.2 5992 6238.6 10330.5 6524.2 10883.8 4616.4 3543.3 10743.1 7464.1 TRUE FALSE FALSE 6334.704061 6509.92178 6469.808004 10287.75513 6446.403176 8626.377194 4745.92376 4623.635859 9564.608808 7723.476919 0.820188126 0.842874504 0.837680758 1.332010859 0.83465041 1.116903343 0.614480215 0.598646944 1.238381225 1 12.91503474 -4.738204987 23.97331816 0.937552878 0.606562769 0.40010726 0.180440637 105.6952609 109053.6643 0.021155553 0.079031541 1.83E-05 4.738204987 -0.33099011 SDAGLES(ph)DTAMK ddPTM_HeLa_Curcumin_4h_R1 4 SDAGLESDTAMK 12 0 Q9NR30 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 0 SDAGLES(0.858)DT(0.142)AMK;SDAGLES(0.724)DT(0.276)AMK;SDAGLES(0.993)DT(0.007)AMK;SDAGLES(0.963)DT(0.037)AMK ;;; 195.71 2.76E-06 269297000 17038 15532.1 17947.2 20811.4 18333.6 20896.9 17821.7 17907.8 17894.1 16879 TRUE FALSE FALSE 15689.42432 16874.62551 18612.33902 20725.28794 18114.98379 16562.64738 18321.72894 23367.80578 15931.162 17465.54399 0.898307223 0.966166615 1.065660424 1.186638558 1.037184058 0.948304123 1.049021373 1.337937472 0.912148056 1 14.09222396 -6.726512941 3.982429426 0.951123313 1.097462752 0.380506987 0.100456557 0.202028599 6.876261671 0.016472509 0.023097725 1.88E-07 6.726512941 0.146339439 SDATNYASHS(ph)PPVNR ddPTM_HeLa_Curcumin_4h_R1 1 SDATNYASHSPPVNR 15 0 Q96FJ0;Q96FJ0-2 Q96FJ0 STAMBPL1 AMSH-like protease 1 0 SDATNYASHS(1)PPVNR 63.212 0.019173 18909000 1336.8 1285.9 1193.9 1391.7 1701.7 1792.1 1224.3 740.72 1318.9 1224.6 TRUE FALSE FALSE 1230.990869 1397.047466 1238.146984 1385.941514 1681.408339 1420.398259 1258.650563 966.5621181 1174.21997 1267.154759 0.971460558 1.102507374 0.977107946 1.093742895 1.326916327 1.12093511 0.993288747 0.762781429 0.926658691 1 10.30737702 -7.273501022 23.53291456 0.986523039 1.063224251 0.073082114 0.134871695 786.6168524 1534729.044 0.023440822 0.026929798 5.33E-08 7.273501022 0.076701211 SDDDDT(ph)NFEES(ph)EDELRDEVVEYLEK ddPTM_HeLa_Curcumin_4h_R1 1 SDDDDTNFEESEDELRDEVVEYLEK 25 1 A0A3B3ITQ6 A0A3B3ITQ6 2 0 S(0.521)DDDDT(0.931)NFEES(0.544)EDELRDEVVEY(0.004)LEK 42.325 0.019957 4269800 1745 1281.2 1344.3 1736.2 1753.1 1720.3 1363.2 1656.1 1575.6 1458.1 TRUE FALSE FALSE 1606.881409 1391.941219 1394.120941 1729.016064 1732.195427 1363.490388 1401.447723 2161.037266 1402.760622 1508.768866 1.065028212 0.922567565 0.924012267 1.14597809 1.148085347 0.903710581 0.9288684 1.432318306 0.929738579 1 10.5591561 -6.243642514 24.85846721 1.014382152 1.092085911 0.156080471 0.145071243 1790.360957 2500757.283 0.020862735 0.034553606 5.71E-07 6.243642514 0.077703759 AS(ph)PTGTPSR ddPTM_HeLa_Curcumin_4h_R1 1 ASPTGTPSR 9 0 Q9UF83 Q9UF83 Uncharacterized protein DKFZp434B061 1 0 AS(0.64)PT(0.355)GT(0.006)PSR 114.86 0.0075812 6261700 2090.1 1896.3 1685.7 2103 2207.8 2348 1587.9 628.21 2128.1 1944.2 TRUE FALSE FALSE 1924.66638 2060.207722 1748.173525 2094.298343 2181.473427 1860.998333 1632.4522 819.7483371 1894.652754 2011.760805 0.956707365 1.024081848 0.868976829 1.041027511 1.084360239 0.925059444 0.811454421 0.407478034 0.941788283 1 10.97424307 -4.2315615 1.7553405 0.984701141 0.18316055 0.902575393 0.057203411 0.198592541 0.564290651 0.007829995 0.270723699 5.87E-05 4.2315615 -0.801540591 down SDDYMPMS(ph)PASVSAPK ddPTM_HeLa_Curcumin_4h_R1 4 SDDYMPMSPASVSAPK 16 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 SDDY(0.006)MPMS(0.984)PAS(0.004)VS(0.006)APK;SDDY(0.249)MPMS(0.749)PAS(0.001)VSAPK;S(0.002)DDY(0.424)MPMS(0.47)PAS(0.046)VS(0.058)APK;SDDYMPMS(0.979)PAS(0.02)VS(0.001)APK ;;; 117.09 0.000485 61025400 17809.4 14928.4 15181.1 15212.7 15724.6 22626.7 20383.7 15280.5 20375.8 15416.6 TRUE FALSE FALSE 16399.7672 16218.74438 15743.72492 15149.75388 15537.09442 17933.66736 20955.61176 19939.45411 18140.62572 15952.3257 1.028048668 1.01670093 0.986923488 0.949689353 0.973970486 1.124203937 1.313639914 1.249940258 1.137177491 1 13.96147915 -4.965718001 3.367636195 1.005067031 1.280839821 0.816691981 0.050412815 0.041117485 0.966700412 0.004437502 0.014644364 1.08E-05 4.965718001 0.27577279 SDEEDEDS(ph)DFGEEQR ddPTM_HeLa_Curcumin_4h_R1 2 SDEEDEDSDFGEEQR 15 0 Q5VW52;Q9HCL2 Q5VW52 GPAM "Glycerol-3-phosphate acyltransferase 1, mitochondrial" 1 0 SDEEDEDS(1)DFGEEQR;SDEEDEDS(1)DFGEEQR ; 185.26 2.45E-05 10728400 2225.12 1841.66 2102.39 2043.79 2263.45 1596.06 1747.06 1335 2073.53 1674.48 TRUE FALSE FALSE 2048.999404 2000.844884 2180.306423 2035.333339 2236.459837 1265.019165 1796.077802 1742.035354 1846.068947 1732.668055 1.182568928 1.154776807 1.258352064 1.174681632 1.290760703 0.730098971 1.036596592 1.005406286 1.065448711 1 10.75877957 -5.268796014 24.99949506 1.125187782 0.935290212 0.45829366 0.113264442 499.7253093 1698180.168 0.018179453 0.041437894 5.39E-06 5.268796014 -0.18989757 SDEEDEDS(ph)DFGEEQRDCYLK ddPTM_HeLa_Curcumin_4h_R1 2 SDEEDEDSDFGEEQRDCYLK 20 1 Q5VW52;Q9HCL2 Q5VW52 GPAM "Glycerol-3-phosphate acyltransferase 1, mitochondrial" 1 0 S(0.013)DEEDEDS(0.975)DFGEEQRDCY(0.013)LK;S(0.003)DEEDEDS(0.997)DFGEEQRDCYLK ; 73.675 0.0021684 26179000 5856.3 3886.7 4933.5 5016.9 4944.9 5288.7 4188.3 4027.1 5939 4762.6 TRUE FALSE FALSE 5392.767675 4222.649029 5116.33985 4996.141397 4885.935297 4191.764004 4305.812426 5254.944252 5287.506559 4928.099996 1.094289418 0.856851329 1.038197247 1.013806822 0.991444025 0.850584202 0.873726676 1.06632257 1.072930047 1 12.26681581 -6.293240649 0.790852474 1.037702021 0.933909251 0.133636361 0.081718784 0.792060182 0.976564148 0.016784428 0.038831226 5.09E-07 6.293240649 -0.10379277 SDEGQLS(ph)PATR ddPTM_HeLa_Curcumin_4h_R1 2 SDEGQLSPATR 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 SDEGQLS(0.996)PAT(0.004)R;SDEGQLS(1)PATR ; 139.19 0.0014688 558570000 5898.7 5078.4 5767.4 6169.4 5942.7 7126.9 5830.9 6206.4 5948.4 4840.8 TRUE FALSE FALSE 5431.811671 5517.354267 5981.144918 6143.872657 5871.837184 5648.700603 5994.499361 8098.702789 5295.875402 5009.01744 1.08440662 1.10148434 1.194075483 1.226562441 1.172253292 1.127706316 1.196741563 1.616824634 1.05726831 1 12.29031192 -1 0.471106824 1.054760218 13.49897758 0.755185208 0.079624121 31.61693141 0.325744118 0.018136726 386.2308548 0.1 1 12.44421736 SDEGQLSPATR ddPTM_HeLa_Curcumin_4h_R1 2 SDEGQLSPATR 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;E9PMV1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 117.02 0.0024922 4781100 2056.21 1738.58 1832 1629.18 1944.84 2073.2 1815.13 1519.11 1647.32 1597.48 FALSE FALSE TRUE 1893.458809 1888.855108 1899.895532 1622.438885 1921.649053 1643.19495 1866.057663 1982.279646 1466.613117 1652.992311 1.145473452 1.142688381 1.149367434 0.981516293 1.162527521 0.994072954 1.128896759 1.199206816 0.887247392 1 10.6908643 -9.387348729 1.10246791 0.999760249 1.111750647 0.392323621 0.07680244 0.52120906 1.129452771 0.044920408 0.011418643 4.10E-10 9.387348729 0.111990398 SDESPKPGK(ac)FQR ddPTM_HeLa_Curcumin_4h_R1 2 SDESPKPGKFQR 12 2 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 0 1 ; SDESPKPGK(1)FQR;SDESPKPGK(1)FQR 96.756 0.0029008 17713500 7788.5 8182.7 8229.1 6210 5943.5 9802.5 6869.2 6539.7 8232.4 7088.6 FALSE TRUE FALSE 7172.032007 8889.976127 8534.077685 6184.304665 5872.627644 7769.351003 7061.931264 8533.624425 7329.326316 7334.928322 0.977791696 1.212005862 1.16348481 0.843130893 0.800638723 1.059226575 0.962781223 1.163423015 0.999236256 1 12.84056715 -7.846416536 0.002561493 0.00011454 2.006343348 0 0.128820796 246703.4497 423.9924757 166511.1876 165560.4071 1.42E-08 7.846416536 2.006228808 HRLDLGEDYPSGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 HRLDLGEDYPSGKK 14 2 O43143 O43143 DHX15 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 0 1 HRLDLGEDYPSGK(1)K 58.752 0.018227 7832300 5557.5 4829.4 5088.1 5183.1 5308.8 7614.2 6041.9 9082.9 5539.6 4429.1 FALSE TRUE FALSE 5117.618011 5246.831817 5276.669462 5161.653706 5245.496027 6034.92909 6211.419453 11852.2344 4931.919739 4583.010895 1.116649759 1.144843845 1.151354335 1.126258223 1.14455238 1.316804439 1.355314136 2.586123984 1.076130922 1 12.16208 -1.898809726 1.00776783 1.079228906 199.9999997 0.971025677 0.074812478 26.29323478 0.257855134 0.012690617 11811.93864 0.012623805 1.898809726 198.9207708 up SDGAPASDS(ph)KPGSSEAAPSSK ddPTM_HeLa_Curcumin_4h_R1 2 SDGAPASDSKPGSSEAAPSSK 21 1 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 1 0 S(0.094)DGAPAS(0.159)DS(0.54)KPGS(0.159)S(0.047)EAAPS(0.001)SK;SDGAPAS(0.045)DS(0.659)KPGS(0.23)S(0.06)EAAPS(0.004)S(0.001)K ; 91.889 0.00018325 34948000 3359.9 2655.2 3139.7 3298.5 3075.06 4558.3 3846.9 2900.33 4008 3164.8 TRUE FALSE FALSE 3093.96037 2884.703657 3256.060044 3284.851681 3038.391918 3612.857197 3954.833661 3784.627266 3568.332428 3274.776564 0.944785181 0.880885642 0.994284642 1.003076581 0.927816557 1.103237771 1.20766519 1.155690225 1.089641494 1 11.67718076 -5.073536001 3.704908738 0.967551055 1.179126463 0.703434426 0.054216975 0.066472273 1.746008068 0.005844158 0.016853726 8.44E-06 5.073536001 0.211575407 SDGAPASDSKPGS(ph)SEAAPSSK ddPTM_HeLa_Curcumin_4h_R1 1 SDGAPASDSKPGSSEAAPSSK 21 1 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 1 0 SDGAPASDS(0.002)KPGS(0.816)S(0.181)EAAPS(0.001)SK 87.228 0.00030221 56186000 4339 2928.2 3095.9 3686.7 3447.3 5569.4 4502.3 5543.8 5333.5 3796.9 TRUE FALSE FALSE 3995.563572 3181.30056 3210.636777 3671.445412 3406.193199 4414.24366 4628.622421 7234.079099 4748.428394 3928.841992 1.016982505 0.80972983 0.817196717 0.934485383 0.866971287 1.123548279 1.17811366 1.841275143 1.208607626 1 11.93988843 -3.977258332 1.373516947 0.966637551 2.784436913 0.83646394 0.116269279 0.604359404 0.60135775 0.014513619 1.829837347 0.000105376 3.977258332 1.817799362 SDGAPASDSKPGSSEAAPSSK ddPTM_HeLa_Curcumin_4h_R1 2 SDGAPASDSKPGSSEAAPSSK 21 1 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 0 0 ; ; 166.28 5.16E-06 17197300 6320.9 4605.2 4365.9 6678.2 5466.6 8069.3 6104 6579.8 7614.7 5016.6 FALSE FALSE TRUE 5820.594095 5003.252968 4527.704095 6650.567378 5401.414365 6395.63622 6275.261812 8585.95073 6779.386461 5190.926477 1.121301587 0.963845855 0.872234295 1.281190826 1.040549195 1.232079909 1.208890521 1.654030503 1.306007028 1 12.34177634 -1.000000003 0.696787084 1.047494764 73.55842001 0.605663808 0.133161507 97.36710387 0.488470897 0.017136645 11009.31497 0.099999999 1.000000003 72.51092524 SDGIYIINLK ddPTM_HeLa_Curcumin_4h_R1 2 SDGIYIINLK 10 0 C9J9K3;A0A0C4DG17;P08865;F8WD59 C9J9K3 RPSA 40S ribosomal protein SA 0 0 ; ; 105.4 0.0067474 1574980 800.73 583.38 721.76 499.42 840.72 1792.99 1379.72 1336.14 668.63 710.49 FALSE FALSE TRUE 737.3513756 633.8047677 748.5090605 497.3535324 830.6949631 1421.103663 1418.43123 1743.522935 595.2829618 735.1794746 1.002954246 0.862108899 1.018131064 0.676506281 1.129921321 1.933002365 1.929367289 2.371560953 0.809711074 1 9.521952679 -5.232379606 2.749565487 0.967270488 2.123833937 0.925844619 0.150277652 0.048465125 0.722922309 0.019878904 0.056172365 5.86E-06 5.232379606 1.156563449 up APSDS(ph)S(ph)LGTPSDGRPELR ddPTM_HeLa_Curcumin_4h_R1 1 APSDSSLGTPSDGRPELR 18 1 M0R0F9;W4VSQ9;Q15642-4;Q15642-2;Q15642-3;Q15642;M0R2H7;Q15642-5 M0R0F9 TRIP10 Cdc42-interacting protein 4 2 0 APS(0.118)DS(0.754)S(0.552)LGT(0.24)PS(0.335)DGRPELR 71.969 0.0091861 55202000 2119.9 1709.5 2041.1 2009.6 1825.9 2390.3 1639 357.03 2252.4 1791.4 TRUE FALSE FALSE 1952.107678 1857.261563 2116.744962 2001.284808 1804.127335 1894.524836 1684.985929 465.8868034 2005.317355 1853.651017 1.053114993 1.001947802 1.141932836 1.079644868 0.973283169 1.022050439 0.909009255 0.25133469 1.08182033 1 10.85615394 -4.231471253 2.608763362 1.032312716 0.05479231 0.960499832 0.047962627 0.073218802 0.597236231 0.006725 0.160871444 5.87E-05 4.231471253 -0.977520406 down SDGSAPSTSTASSK(ac)LK ddPTM_HeLa_Curcumin_4h_R1 1 SDGSAPSTSTASSKLK 16 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 0 1 SDGSAPSTSTASSK(1)LK 260.7 6.71E-62 2081100 636.4 351.56 360.41 408.5 241.3 384.16 337.1 415.81 443.44 592.63 FALSE TRUE FALSE 586.0282685 381.9472799 373.7671116 406.8097352 238.4226551 304.4808856 346.5581187 542.5885548 394.7957414 613.2238484 0.955651464 0.622851314 0.609511702 0.663395164 0.388801994 0.49652486 0.565141293 0.884813199 0.643803633 1 9.260269995 -7.25566615 3.693898382 0.981574726 0.589383152 0.289047298 0.160362036 0.093603285 2.797084182 0.020553328 0.024402687 5.55E-08 7.25566615 -0.392191574 SDGSGESAQPPEDSS(ph)PPASSESSSTR ddPTM_HeLa_Curcumin_4h_R1 1 SDGSGESAQPPEDSSPPASSESSSTR 26 0 Q7Z6Z7-2;Q7Z6Z7-3;Q7Z6Z7 Q7Z6Z7-2 HUWE1 E3 ubiquitin-protein ligase HUWE1 1 0 SDGSGESAQPPEDS(0.03)S(0.969)PPASSESSSTR 130.77 2.39E-08 5259000 2161.3 2136.8 1799.7 2213.1 2267.7 2597.3 1793.4 1710.1 2382.5 2245.4 TRUE FALSE FALSE 1990.230824 2321.495471 1866.398465 2203.942779 2240.659159 2058.590702 1843.717977 2231.501618 2121.145711 2323.427483 0.856592615 0.999168465 0.803295338 0.948573947 0.964376627 0.886014613 0.793533687 0.960435234 0.912938203 1 11.1820389 -9.474693411 1.122552857 1.002034893 0.896483867 0.030550356 0.070565383 0.560590454 1.223577431 0.047783783 0.010833867 3.35E-10 9.474693411 -0.105551026 SDHTLTS(ph)PGGGGK ddPTM_HeLa_Curcumin_4h_R1 1 SDHTLTSPGGGGK 13 0 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;H7C2R5 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 SDHTLT(0.046)S(0.954)PGGGGK 104.9 0.0024285 23373000 4278.2 3050.9 3336.6 3543.5 5317.4 11261 4746 1278.5 5651.6 3024.8 TRUE FALSE FALSE 3939.575956 3314.606201 3460.257331 3528.837936 5253.993478 8925.341662 4879.159987 1668.308765 5031.63362 3129.911575 1.258686024 1.059009535 1.105544757 1.127456112 1.678639588 2.851627418 1.558881096 0.533021053 1.607596093 1 11.61190618 -5.748412427 6.218806247 1.118045837 1.737874592 0.131531977 0.547952729 0.17895435 25.62999986 0.076391508 0.14900589 1.78E-06 5.748412427 0.619828755 SDIS(ph)PLTPR ddPTM_HeLa_Curcumin_4h_R1 2 SDISPLTPR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(0.011)DIS(0.988)PLTPR;S(0.121)DIS(0.878)PLT(0.001)PR ; 113.69 0.0079595 317390000 7612.4 6502.8 6795.6 7511.7 6723.6 6515.1 3832.4 5421.5 7772.1 6352.4 TRUE FALSE FALSE 7009.870507 7064.873056 7047.450914 7480.618576 6643.425461 5163.79482 3939.92683 7074.490392 6919.520075 6573.145427 1.066440806 1.074808573 1.07215807 1.138057671 1.010691994 0.78558962 0.599397484 1.076271698 1.052695418 1 12.68236819 -5.304877365 5.13095795 1.046384736 0.797737547 0.475238784 0.114057469 0.116090709 7.520284734 0.015079453 0.035197653 4.96E-06 5.304877365 -0.248647189 SDISPLT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 SDISPLTPR 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 SDISPLT(1)PR;SDISPLT(1)PR ; 126.03 0.013552 1402960000 7857.1 6842.1 6025.1 7201 6801.4 7045.4 5568.1 10418.9 7751.5 6905.3 TRUE FALSE FALSE 7235.202244 7433.500636 6248.395506 7171.20417 6720.297747 5584.104622 5724.3259 13595.57465 6901.179843 7145.258661 1.012587869 1.040340314 0.874481359 1.00363115 0.940525468 0.781511893 0.801136274 1.902740725 0.96584045 1 12.80277052 -4.255072391 24.9490764 0.969865851 1.902741154 0.909456789 0.09097373 163.470094 640540.4643 0.013671459 0.172203507 5.56E-05 4.255072391 0.932875303 SDK(ac)PDMAEIEK ddPTM_HeLa_Curcumin_4h_R1 1 SDKPDMAEIEK 11 1 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 1 SDK(1)PDMAEIEK 97.779 0.010356 6431800 4537.5 3759.8 4327.7 4376.2 4619.2 5094.8 4382.1 4730.3 4023.1 3989.1 FALSE TRUE FALSE 4178.352087 4084.780359 4488.088369 4358.092444 4564.119057 4038.08105 4505.049932 6172.546694 3581.775995 4127.720928 1.012266129 0.989597027 1.087304216 1.055810826 1.105723748 0.978283445 1.0914134 1.49538857 0.867736956 1 12.01112972 -4.266239292 3.264036776 1.019882138 1.559343661 0.839628019 0.062961392 0.062559711 1.064951515 0.005908683 0.084404112 5.42E-05 4.266239292 0.539461523 EGVVAAAEK(ac)TK ddPTM_HeLa_Curcumin_4h_R1 1 EGVVAAAEKTK 11 1 D6RA31;H6UYS7;E7EPV7;G4Y816;A0A669KB41;A0A669KBH5;P37840-2;P37840-3;Q16143;P37840 D6RA31 SNCA;SNCB Alpha-synuclein;Beta-synuclein 0 1 EGVVAAAEK(1)TK 110.86 0.0042391 3837300 898.71 849.69 969.03 1159.1 719.7 1500.5 1099.4 1648.9 947.32 932.24 FALSE TRUE FALSE 827.5761552 923.1334175 1004.943104 1154.303951 711.1180476 1189.279386 1130.246205 2151.642019 843.4013661 964.6352706 0.857916127 0.956976637 1.041785569 1.196622171 0.73718852 1.232879848 1.171682437 2.230523893 0.87432151 1 9.913839751 -1.885788865 1.034570858 0.950675367 199.9999969 0.879158396 0.138012547 55.82783071 0.492678764 0.01973248 25852.03417 0.013008018 1.885788865 199.0493216 up SDKNQQGFS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 SDKNQQGFSPK 11 1 D6RCT7;C9JKA9;Q9NS87-4;Q9NS87-2;Q9NS87 D6RCT7 KIF15 Kinesin-like protein;Kinesin-like protein KIF15 1 0 SDKNQQGFS(1)PK;SDKNQQGFS(1)PK;SDKNQQGFS(1)PK ;; 140.82 0.01108 170362500 17127 14645.6 15022.4 16157.5 14935.6 16864.6 12213.6 12224.6 18370.8 14309.5 TRUE FALSE FALSE 15771.37988 15911.5004 15579.14336 16090.64455 14757.50272 13366.69186 12556.28074 15951.82426 16355.5692 14806.75406 1.06514769 1.074610974 1.052164661 1.086709787 0.996673725 0.902742884 0.848010354 1.077334317 1.104601936 1 13.85396779 -5.486096261 5.319448576 1.040556476 0.934662929 0.406577941 0.062210549 0.151145053 11.08662521 0.008416368 0.01864367 3.27E-06 5.486096261 -0.105893547 SDKS(ph)PDLAPTPAPQS(ph)TPR ddPTM_HeLa_Curcumin_4h_R1 1 SDKSPDLAPTPAPQSTPR 18 1 F8WAE5;Q9BY44-2;Q9BY44-4;Q9BY44-3;Q9BY44 F8WAE5 EIF2A "Eukaryotic translation initiation factor 2A;Eukaryotic translation initiation factor 2A, N-terminally processed" 2 0 S(0.111)DKS(0.889)PDLAPT(0.162)PAPQS(0.541)T(0.297)PR 110.94 0.00051421 12603000 2640.2 2372.3 2077 2167.9 2517.6 5295.1 4034.9 1800.4 2564.8 1889.4 TRUE FALSE FALSE 2431.225384 2577.351041 2153.975447 2158.929804 2487.579264 4196.836572 4148.108435 2349.333672 2283.447857 1955.056509 1.243557602 1.318300023 1.101745876 1.104280001 1.272382283 2.146657425 2.121733267 1.201670469 1.167970259 1 10.93299459 -5.400455615 5.392628391 1.134922247 1.848876119 0.578117554 0.255310387 0.109958413 4.399221151 0.035725905 0.08104288 3.98E-06 5.400455615 0.713953872 SDKS(ph)PDLAPTPAPQST(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SDKSPDLAPTPAPQSTPR 18 1 F8WAE5;Q9BY44-2;Q9BY44-4;Q9BY44-3;Q9BY44 F8WAE5 EIF2A "Eukaryotic translation initiation factor 2A;Eukaryotic translation initiation factor 2A, N-terminally processed" 2 0 S(0.009)DKS(0.991)PDLAPT(0.006)PAPQS(0.264)T(0.73)PR 118.05 0.0017417 6689400 2020.8 1516.1 1494.8 2033.5 1971.3 4302.8 3516.3 1369.4 2059.4 1464.2 TRUE FALSE FALSE 1860.851548 1647.144928 1550.198603 2025.085916 1947.793535 3410.350777 3614.957914 1786.923756 1833.488972 1515.080841 1.228219312 1.087166364 1.023178804 1.336619051 1.2856037 2.250936508 2.385983518 1.179424693 1.21015917 1 10.56517906 -5.394978784 4.536910379 1.122078992 1.9791377 0.561318176 0.312589497 0.109550149 3.550907989 0.042412465 0.097522226 4.03E-06 5.394978784 0.857058708 SDKS(ph)PDLAPTPAPQSTPR ddPTM_HeLa_Curcumin_4h_R1 1 SDKSPDLAPTPAPQSTPR 18 1 F8WAE5;Q9BY44-2;Q9BY44-4;Q9BY44-3;Q9BY44 F8WAE5 EIF2A "Eukaryotic translation initiation factor 2A;Eukaryotic translation initiation factor 2A, N-terminally processed" 1 0 S(0.077)DKS(0.923)PDLAPTPAPQSTPR 101.53 0.00057256 60518000 4258.3 3566.9 3816.9 4103.8 3447.4 5225.3 3679.7 3950 4372.6 4017.5 TRUE FALSE FALSE 3921.251062 3875.206942 3958.357672 4086.819563 3406.292007 4141.513879 3782.942479 5154.336816 3892.93672 4157.107826 0.943264218 0.932188219 0.952190282 0.983092028 0.819389862 0.996248847 0.909993832 1.239885284 0.93645315 1 12.02136445 -4.255511048 24.79315658 0.957352905 1.239885422 0.74566632 0.05154228 232.5077318 972350.0452 0.007094387 0.085020339 5.55E-05 4.255511048 0.282532517 AVTDFVIPECQKKS(ph)PISK ddPTM_HeLa_Curcumin_4h_R1 1 AVTDFVIPECQKKSPISK 18 2 Q6P0N0 Q6P0N0 MIS18BP1 Mis18-binding protein 1 1 0 AVT(0.001)DFVIPECQKKS(0.868)PIS(0.132)K 50.053 0.014455 41927000 2670.4 1845.7 2357.6 2848.1 2107.6 3099 1937.9 518.19 3378.5 2607.3 TRUE FALSE FALSE 2459.035022 2005.234084 2444.97473 2836.315317 2082.468247 2456.232467 1992.272258 676.1837455 3007.887003 2697.903481 0.911461451 0.74325642 0.906249889 1.051303479 0.771883895 0.910422661 0.738452014 0.250633038 1.114897929 1 11.39762302 -4.230567819 1.747978267 0.9316657 1.49E-16 0.784861918 0.106976639 0.298990865 0.839032252 0.013561048 0.472628025 5.88E-05 4.230567819 -0.9316657 down SDLPGSDKDTEDGSAWKQDPFQES(ph)GLHLSPTAAEAK ddPTM_HeLa_Curcumin_4h_R1 1 SDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAK 36 2 H3BN50;H3BQS0;Q15599-3;Q15599 H3BN50 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 0 SDLPGSDKDTEDGS(0.001)AWKQDPFQES(0.735)GLHLS(0.204)PT(0.059)AAEAK 59.426 0.00013239 20573000 904.02 688.42 812.69 720.66 852.12 1436.7 966.63 309.76 1253.5 722.73 TRUE FALSE FALSE 832.4658631 747.9239573 842.8090063 717.6780999 841.9590255 1138.712225 993.7510362 404.204398 1115.994186 747.8448137 1.113153221 1.000105829 1.126983822 0.9596618 1.125847248 1.52265845 1.328819854 0.540492346 1.492280438 1 9.546595115 -5.528942887 24.69497134 1.050192212 1.179436444 0 0.276928332 311.44704 1268304.21 0.032957584 0.066059734 2.96E-06 5.528942887 0.129244233 SDLPGSDKDTEESGLHLS(ph)PTAAEAK ddPTM_HeLa_Curcumin_4h_R1 2 SDLPGSDKDTEESGLHLSPTAAEAK 25 1 Q15599-2 Q15599-2 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 0 S(0.001)DLPGS(0.003)DKDT(0.002)EES(0.014)GLHLS(0.677)PT(0.304)AAEAK;S(0.001)DLPGS(0.007)DKDT(0.006)EES(0.004)GLHLS(0.638)PT(0.344)AAEAK ; 47.728 0.011513 37103000 7875.5 6742 5772.7 6073.6 8312.6 11720.6 7025.9 2816.08 9240.5 6941.5 TRUE FALSE FALSE 7252.145865 7324.748438 5986.64134 6048.469052 8213.477674 9289.615442 7223.027845 3674.689828 8226.840269 7182.716608 1.009666156 1.01977411 0.833478705 0.842086551 1.143505741 1.293328966 1.005612255 0.511601672 1.145366122 1 12.81031388 -4.262095499 8.246702637 1.012112274 0.508160747 0.578636145 0.132341513 0.048981359 46.49764068 0.017836285 0.139104954 5.47E-05 4.262095499 -0.503951527 SDLTSR ddPTM_HeLa_Curcumin_4h_R1 1 SDLTSR 6 0 Q8NCX0 Q8NCX0 CCDC150 Coiled-coil domain-containing protein 150 0 0 92.279 0.0061443 3135800 2861.4 2807.2 2568.8 2508.8 2626.2 2731.4 2752.7 2173.9 2448.2 2441.5 FALSE FALSE TRUE 2634.917171 3049.841859 2664.001988 2498.41925 2594.88428 2164.876851 2829.933353 2836.712103 2179.638585 2526.341943 1.042977249 1.207216572 1.05448987 0.988947382 1.027131061 0.856921549 1.120170356 1.122853583 0.862764675 1 11.30283421 -8.706311636 1.280394217 1.005792653 1.048793766 0.11133903 0.098607341 1.183584351 3.885937474 0.029651207 0.01675683 1.97E-09 8.706311636 0.043001113 SDLYSSGR ddPTM_HeLa_Curcumin_4h_R1 2 SDLYSSGR 8 0 P38159;P38159-2;H3BUY5 P38159 RBMX "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed" 0 0 ; ; 157.21 6.75E-06 9232500 14944.2 11734.7 12351.6 12931.7 13070.7 15293.8 21730.8 13709.6 13659.9 12196.5 FALSE FALSE TRUE 13761.3508 12748.99518 12809.36116 12878.19205 12914.84044 12121.69348 22340.50776 17889.59393 12161.44315 12620.32747 1.090411547 1.010195275 1.014978509 1.02043248 1.023336397 0.960489616 1.770200323 1.417522166 0.96363927 1 13.62346172 -4.768005293 24.99999512 1.031868678 1.593861288 0.874907278 0.087944823 28.54178436 108675.9215 0.010758591 0.033405353 1.71E-05 4.768005293 0.56199261 SDNENDGYVPDVEMS(ph)DSESEASEKK ddPTM_HeLa_Curcumin_4h_R1 1 SDNENDGYVPDVEMSDSESEASEKK 25 1 Q6IE81;Q6IE81-2 Q6IE81 JADE1 Protein Jade-1 1 0 SDNENDGY(0.087)VPDVEMS(0.702)DS(0.204)ES(0.005)EAS(0.002)EKK 59.359 0.0025259 4915100 736.08 626.73 790.15 955.27 1223.9 1032 761.68 485.35 1084.3 664.68 TRUE FALSE FALSE 677.8184913 680.9017485 819.4336541 951.3173459 1209.305792 817.951567 783.0506908 633.3309807 965.3550028 687.7775805 0.985519898 0.990002826 1.191422456 1.383175859 1.758280331 1.189267563 1.13852314 0.920836908 1.403586029 1 9.425798279 -6.64056792 3.636875 0.99244378 1.291837515 0.051598456 0.238252036 0.215919546 5.513328901 0.033275406 0.047814363 2.29E-07 6.64056792 0.299393735 SDPIMLLK(ac)DR ddPTM_HeLa_Curcumin_4h_R1 1 SDPIMLLKDR 10 1 P08559-3;P08559;P08559-2;P08559-4;Q5JPU3 P08559-3 PDHA1 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial" 0 1 SDPIMLLK(1)DR 104.43 0.0069132 1372500 265.39 200.76 221.53 340.48 303.16 245.21 199.51 203.36 191.59 0 FALSE TRUE FALSE 244.3841015 218.1127998 229.7400967 339.071184 299.545015 194.3506819 205.1077136 265.3635278 170.5730563 0 0 SDPVVSYR ddPTM_HeLa_Curcumin_4h_R1 2 SDPVVSYR 8 0 P13639 P13639 EEF2 Elongation factor 2 0 0 ; ; 143.85 0.0004719 26420000 11523 8879.6 10106.8 9921.9 9772.2 11796.4 8760.2 9354.2 10688.3 9801.4 FALSE FALSE TRUE 10610.94239 9647.113057 10481.3669 9880.845807 9655.672897 9349.693667 9005.987635 12206.25252 9515.820231 10141.99792 1.046237879 0.951204401 1.033461748 0.974250427 0.9520484 0.921878878 0.887989497 1.203535301 0.938258941 1 13.30805426 -7.267677667 24.27472289 1.021834553 0.982412881 0 0.08608194 856.109145 3331328.596 0.013130909 0.01521902 5.40E-08 7.267677667 -0.039421671 SDQDYILK ddPTM_HeLa_Curcumin_4h_R1 1 SDQDYILK 8 0 Q9UQ80;Q9UQ80-2;F8VR77;H0YIN7;F8W0A3;F8VZ69 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 0 115.7 0.0033367 5142600 3950 3565.5 3234.3 3419 3704.2 5315.7 4753.5 4128.9 4285.7 3278.8 FALSE FALSE TRUE 3637.353332 3873.685932 3354.166003 3404.853084 3660.029834 4213.1639 4886.870417 5387.782603 3815.569432 3392.738056 1.072099665 1.141758034 0.988630996 1.00357087 1.0787835 1.24181821 1.440391311 1.588033769 1.124628359 1 11.72823433 -4.80189023 1.443933309 1.037229776 1.610111399 0.928464456 0.050974705 0.087743933 0.295398171 0.00722075 0.054195838 1.58E-05 4.80189023 0.572881622 SDS(ph)APPTPVNR ddPTM_HeLa_Curcumin_4h_R1 1 SDSAPPTPVNR 11 0 A2A2F0;Q86X10-4;Q86X10-2;Q86X10-3;Q86X10 A2A2F0 RALGAPB Ral GTPase-activating protein subunit beta 1 0 S(0.34)DS(0.66)APPTPVNR 142.19 0.0012178 19948000 3060.9 3004.2 2354.1 2378.5 2346.9 3066.4 2224.4 1858.4 2968.1 2831.3 TRUE FALSE FALSE 2818.626535 3263.869662 2441.345017 2368.658397 2318.91475 2430.394075 2286.810677 2425.017605 2642.506856 2929.687464 0.962091202 1.114067525 0.833312443 0.808502076 0.791522911 0.829574521 0.780564721 0.827739353 0.901975684 1 11.51653105 -6.625314868 7.913625336 0.99134517 0.807893164 0.756620642 0.050898948 0.069885094 4.847309339 0.006502114 0.009201637 2.37E-07 6.625314868 -0.183452006 SDS(ph)DSSTLAK ddPTM_HeLa_Curcumin_4h_R1 1 SDSDSSTLAK 10 0 Q6AWC2-7;Q6AWC2-3;Q6AWC2-2;Q6AWC2-4;Q6AWC2;Q6AWC2-6 Q6AWC2-7 WWC2 Protein WWC2 1 0 S(0.126)DS(0.858)DS(0.015)STLAK 126.03 0.003523 78938000 2674.9 2933.4 2998.3 2606.5 2584.1 2796.7 2284.8 1528 2399.3 2400.6 TRUE FALSE FALSE 2463.178842 3186.950025 3109.419636 2595.714994 2553.286295 2216.632895 2348.905339 1993.880166 2136.102793 2484.020671 0.99160964 1.282980477 1.251768824 1.044965134 1.02788448 0.892356863 0.945606196 0.802682598 0.859937607 1 11.27846146 -5.25156615 2.772491259 1.044390621 0.879438238 0.317453963 0.12210372 0.306768476 4.674659558 0.018148209 0.050369783 5.60E-06 5.25156615 -0.164952383 SDS(ph)DSSTLPR ddPTM_HeLa_Curcumin_4h_R1 1 SDSDSSTLPR 10 0 Q9ULE0 Q9ULE0 WWC3 Protein WWC3 1 0 S(0.124)DS(0.875)DS(0.001)STLPR 124.39 0.0038071 50425000 2062 1957.3 1730 2147.1 2292.4 2412.2 1809.7 1068.5 2548.4 2159.5 TRUE FALSE FALSE 1898.790524 2126.48029 1794.115322 2138.215869 2265.064627 1911.882529 1860.475311 1394.280731 2268.846896 2234.542464 0.849744659 0.951640134 0.802900527 0.956892027 1.013659245 0.855603579 0.832597877 0.623966988 1.015351882 1 11.12576375 -4.179545266 1.462650737 0.925812431 0.462593024 0.655276987 0.06842955 0.730850236 1.209632288 0.010613902 0.518195125 6.61E-05 4.179545266 -0.463219406 SDS(ph)DSSTLSK ddPTM_HeLa_Curcumin_4h_R1 1 SDSDSSTLSK 10 0 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 0 S(0.002)DS(0.939)DS(0.043)S(0.012)T(0.004)LSK 163.46 0.0005949 166190000 6097.1 8570.9 6687 5170 5715.8 5016.6 3486.5 1262.7 4233.2 5955.6 TRUE FALSE FALSE 5614.508101 9311.730405 6934.826102 5148.60791 5647.642818 3976.100611 3584.321807 1647.691417 3768.828551 6162.556657 0.911067989 1.511017411 1.125316405 0.835466219 0.91644477 0.645203092 0.581629023 0.267371403 0.61156899 1 12.58931329 -4.764664724 0.97304937 1.011720443 0.199083955 0.550667329 0.217516177 0.51962822 0.606749949 0.029925605 0.366489743 1.72E-05 4.764664724 -0.812636488 SDS(ph)DTEGLLFSR ddPTM_HeLa_Curcumin_4h_R1 1 SDSDTEGLLFSR 12 0 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 S(0.004)DS(0.993)DT(0.002)EGLLFSR 181.76 8.19E-05 6623200 1657 1282.9 1614.2 1737.3 2092.2 2124.5 2054.4 717.45 1583.7 1376.9 TRUE FALSE FALSE 1525.846702 1393.78816 1674.023672 1730.111513 2067.251881 1683.854752 2112.040935 936.1972023 1409.972072 1424.747173 1.070959628 0.978270522 1.174961919 1.214328792 1.450960508 1.181862147 1.482397 0.657097077 0.989629669 1 10.47649021 -6.624302175 4.610818859 1.030529586 1.22380288 0.144744438 0.211853927 0.28081381 10.35134201 0.030508235 0.043544031 2.38E-07 6.624302175 0.193273294 TDGFAEAIHS(ph)PQVAGVPR ddPTM_HeLa_Curcumin_4h_R1 5 TDGFAEAIHSPQVAGVPR 18 0 P12270 P12270 TPR Nucleoprotein TPR 1 0 TDGFAEAIHS(1)PQVAGVPR;T(0.006)DGFAEAIHS(0.994)PQVAGVPR;TDGFAEAIHS(1)PQVAGVPR;T(0.008)DGFAEAIHS(0.992)PQVAGVPR;T(0.001)DGFAEAIHS(0.999)PQVAGVPR ;;;; 116.87 0.00031494 659024000 11890 7243.73 10070.7 9821.38 10785.2 16620.6 23661.1 56381.4 10922.6 7153.97 TRUE FALSE FALSE 10948.89395 7869.845744 10443.929 9780.741732 10656.59353 13173.30021 24324.96679 73571.82931 9724.418107 7402.569925 1.479066603 1.063123459 1.410851786 1.321262998 1.43958026 1.779557686 3.286016482 9.938687518 1.31365434 1 12.8538105 -4.106544876 1.675159166 1.25713355 15.76793186 0.994583822 0.190269926 0.086654756 0.170893868 0.033614371 2.273231501 7.82E-05 4.106544876 14.51079831 up SDS(ph)DYDLSPK ddPTM_HeLa_Curcumin_4h_R1 1 SDSDYDLSPK 10 0 A0A1B0GW84;A0A087WSZ7;Q08499-2;Q08499-10;Q08499-9;Q08499-11;Q08499;A0A1W2PQN6;E9PMG3;Q07343-3;Q07343;Q08499-6;Q08499-7;Q08499-12 A0A1B0GW84;Q08499-6 PDE4D;PDE4B "cAMP-specific 3,5-cyclic phosphodiesterase 4D;cAMP-specific 3,5-cyclic phosphodiesterase 4B" 1 0 S(0.013)DS(0.985)DYDLS(0.001)PK 150.09 0.00078757 168980000 3084.1 2299.6 2264.8 2728.7 2716.5 4627.7 4671.5 2075.3 2674.8 2912 TRUE FALSE FALSE 2839.990231 2498.367177 2348.73548 2717.409362 2684.107512 3667.862855 4802.569717 2708.049416 2381.381132 3013.191783 0.942518909 0.8291431 0.779484231 0.901837506 0.890785488 1.217268305 1.593848007 0.898731183 0.790318474 1 11.55707678 -5.193111225 5.245848544 0.936199532 1.279827182 0.44039082 0.176127924 0.144340409 7.671364496 0.022477388 0.058550231 6.41E-06 5.193111225 0.34362765 SDS(ph)FENPVLQQHFR ddPTM_HeLa_Curcumin_4h_R1 2 SDSFENPVLQQHFR 14 0 P12956;P12956-2;B1AHC9 P12956 XRCC6 X-ray repair cross-complementing protein 6 1 0 S(0.138)DS(0.862)FENPVLQQHFR;S(0.35)DS(0.65)FENPVLQQHFR ; 164.53 0.0001031 48811000 5379.8 4464.9 3601.7 3756 4640 8266.3 7206.6 2582.5 7183.2 4009 TRUE FALSE FALSE 4953.983153 4850.826061 3735.18217 3740.458667 4584.67103 6551.7762 7408.7978 3369.892362 6395.220931 4148.312452 1.194216494 1.169349252 0.900410038 0.901682 1.10518942 1.579383491 1.785978729 0.812352589 1.541643983 1 12.01830885 -5.337889449 7.047935338 1.070356963 1.43102668 0.144392344 0.290009887 0.228614326 18.17267574 0.033935618 0.076410314 4.59E-06 5.337889449 0.360669717 SDS(ph)GGSSSEPFDR ddPTM_HeLa_Curcumin_4h_R1 1 SDSGGSSSEPFDR 13 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 0 SDS(0.534)GGS(0.295)S(0.086)S(0.086)EPFDR 206.46 4.82E-09 80393000 1295.1 1050.6 905.5 1108.8 1167.7 1231.1 1076.2 508.7 1381.9 1033.8 TRUE FALSE FALSE 1192.591468 1141.409183 939.0586266 1104.212079 1153.77594 975.7559826 1106.395276 663.8002882 1230.309027 1069.724473 1.114858544 1.067012311 0.877850933 1.03223971 1.078573006 0.912156361 1.034280605 0.62053389 1.150117678 1 10.06302354 -3.89759378 1.73523608 1.03782474 3.63E-13 0.688238624 0.081675721 1.247014134 1.599271604 0.011234978 2.918440693 0.000126592 3.89759378 -1.03782474 SDS(ph)LLSFR ddPTM_HeLa_Curcumin_4h_R1 2 SDSLLSFR 8 0 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 0 S(0.165)DS(0.835)LLSFR;S(0.143)DS(0.856)LLSFR ; 162.64 0.00068785 135365000 8263.4 6459.9 8151.8 8253.5 8358.5 10604.7 8252.5 5882.8 7998.9 6993.5 TRUE FALSE FALSE 7609.343171 7018.264971 8453.912879 8219.349204 8258.830347 8405.16568 8484.04294 7676.438639 7121.440682 7236.523604 1.051519153 0.969839298 1.168228467 1.135814606 1.141270422 1.161492194 1.172392077 1.060790935 0.984096933 1 12.82108108 -6.754129896 24.99999964 1.020921565 1.142315256 0.761300407 0.037380242 64.41472696 220311.5698 0.00567343 0.007930156 1.76E-07 6.754129896 0.121393691 SDS(ph)PEIPFQAAAGPSDGLDAS(ph)SPGNSFVGLR ddPTM_HeLa_Curcumin_4h_R1 1 SDSPEIPFQAAAGPSDGLDASSPGNSFVGLR 31 0 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 S(0.478)DS(0.522)PEIPFQAAAGPS(0.084)DGLDAS(0.509)S(0.326)PGNS(0.081)FVGLR 71.969 0.00017166 3546100 1016.4 681.37 859.18 878.44 725.83 1145.5 950.89 788.75 963.99 599.81 TRUE FALSE FALSE 935.9508675 740.2645867 891.0219666 874.805248 717.1749513 907.9103876 977.5694142 1029.236244 858.2427088 620.6533529 1.508009041 1.192718259 1.435619356 1.409490892 1.155516115 1.46283007 1.575065066 1.658310938 1.38280524 1 9.27764391 -11.57470915 0.310548899 4.83E-12 1.461073225 0.051918491 0.187939361 8.888078999 0.348879298 5.708841302 0.063933137 2.66E-12 11.57470915 1.461073225 SDS(ph)PEIPFQAAAGPSDGLDASS(ph)PGNSFVGLR ddPTM_HeLa_Curcumin_4h_R1 1 SDSPEIPFQAAAGPSDGLDASSPGNSFVGLR 31 0 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 S(0.205)DS(0.795)PEIPFQAAAGPSDGLDAS(0.299)S(0.642)PGNS(0.059)FVGLR 95.097 9.04E-08 3495300 2851 2396 2611.5 2212.6 2496.7 2952.6 2278.7 2576.1 3044.3 2571.6 TRUE FALSE FALSE 2625.340342 2603.099564 2708.284487 2203.444847 2466.928483 2340.197477 2342.634189 3361.541031 2710.347906 2660.962909 0.986612904 0.978254734 1.01778363 0.828062969 0.927081124 0.879455129 0.880370854 1.263279928 1.01855907 1 11.37773269 SDS(ph)PEIPFQAAAGPSDGLDASSPGNSFVGLR ddPTM_HeLa_Curcumin_4h_R1 1 SDSPEIPFQAAAGPSDGLDASSPGNSFVGLR 31 0 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 S(0.199)DS(0.801)PEIPFQAAAGPSDGLDASSPGNSFVGLR 136.02 7.88E-13 66058000 3692.8 3485.1 3377.4 3627.6 3245.4 4317.5 3348.8 2104 3959.9 3553.2 TRUE FALSE FALSE 3400.510983 3786.336515 3502.569415 3612.589952 3206.700725 3422.001832 3442.758315 2745.499914 3525.508877 3676.673436 0.924887957 1.029826712 0.952646319 0.982570254 0.872174475 0.930733146 0.936378598 0.746734776 0.958885509 1 11.84418533 -3.377556935 0.929911478 0.964823701 6.00E-31 0.691887938 0.041483398 4.150439288 0.808516957 0.006850537 6.002130312 0.000419221 3.377556935 -0.964823701 SDS(ph)PSVGETER ddPTM_HeLa_Curcumin_4h_R1 2 SDSPSVGETER 11 0 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 0 S(0.011)DS(0.948)PS(0.041)VGETER;S(0.007)DS(0.896)PS(0.066)VGET(0.031)ER ; 134.18 0.0022187 22133000 7478.4 7376.9 6704.4 7263.6 6595.9 7094.3 6072.9 6377 8083.8 7109.9 TRUE FALSE FALSE 6886.476749 8014.526365 6952.870962 7233.545148 6517.2482 5622.862211 6243.28923 8321.317944 7197.027365 7356.968496 0.93604815 1.089378916 0.94507282 0.983223613 0.885860556 0.764290647 0.848622532 1.131079731 0.978259914 1 12.8448957 -5.762174392 24.93837051 0.977840513 0.893033817 0.135651024 0.095417931 27.43777158 931004.1127 0.013633491 0.025821434 1.73E-06 5.762174392 -0.084806696 SDS(ph)PVPTAPTSGGPK ddPTM_HeLa_Curcumin_4h_R1 1 SDSPVPTAPTSGGPK 15 0 Q86U44;B4E349;F5H6D8;B4DTN4 Q86U44 METTL3 N6-adenosine-methyltransferase 70 kDa subunit 1 0 S(0.215)DS(0.785)PVPTAPTSGGPK 138.28 0.00056808 8150400 3893.3 3091.1 3968.2 3592.8 4519.3 3246 3048.3 1035.5 3149.6 3009.6 TRUE FALSE FALSE 3585.141197 3358.28091 4115.264983 3577.933946 4465.410299 2572.74301 3133.827094 1351.219183 2804.09676 3114.183376 1.151229958 1.078382518 1.321458786 1.148915627 1.433894463 0.826137288 1.006307823 0.433891977 0.900427631 1 11.60463818 -4.101753972 1.478814432 1.112954307 3.80E-14 0.592862797 0.168143144 0.871638035 1.284810636 0.022655245 1.581643114 7.91E-05 4.101753972 -1.112954307 VSSPLSPLSPGIKS(ph)PTIPR ddPTM_HeLa_Curcumin_4h_R1 2 VSSPLSPLSPGIKSPTIPR 19 1 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 1 0 VS(0.001)S(0.002)PLSPLS(0.008)PGIKS(0.743)PT(0.246)IPR;VSSPLSPLS(0.003)PGIKS(0.843)PT(0.154)IPR ; 147.06 6.74E-05 837910000 4372 4080.6 3696.2 4094.2 4085 4182.9 2746.9 1123.82 4880.8 3930.1 TRUE FALSE FALSE 4025.951587 4433.308881 3833.184424 4077.259285 4036.289043 3315.319389 2823.970621 1466.467545 4345.388451 4066.670682 0.989987117 1.090156845 0.942585403 1.002603752 0.992529112 0.815241668 0.694418319 0.360606417 1.068537089 1 11.98963245 -4.229493078 0.992999142 1.001815503 3.34E-20 0.95432902 0.045019351 0.239998534 0.173341195 0.005711018 0.259767085 5.90E-05 4.229493078 -1.001815503 down SDS(ph)QASLTVPLS(ph)PQVVR ddPTM_HeLa_Curcumin_4h_R1 1 SDSQASLTVPLSPQVVR 17 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 2 0 S(0.28)DS(0.72)QASLTVPLS(1)PQVVR 125.59 0.00028892 0 1276.2 1209.3 1025.1 1248.7 1127.6 1246.2 833.35 1081.5 1300.4 1447.4 TRUE FALSE FALSE 1175.187423 1313.826503 1063.091108 1243.53321 1114.154106 987.7240724 856.7315582 1411.244371 1157.749373 1497.697042 0.784662979 0.877231153 0.709817191 0.830296899 0.743911536 0.659495241 0.572032617 0.942276263 0.773019737 1 10.54853011 -9.981267413 0.247098541 1.214239083 0.706530537 0.01555859 0.121488586 5.125962622 0.313011303 0.794368296 0.079065583 1.04E-10 9.981267413 -0.507708546 SSQSEGIFLGS(ph)ES(ph)DEDSVR ddPTM_HeLa_Curcumin_4h_R1 1 SSQSEGIFLGSESDEDSVR 19 0 Q9BYW2;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 2 0 SSQS(0.005)EGIFLGS(0.852)ES(0.997)DEDS(0.145)VR 112.44 0.00096356 6293000 989.94 936.51 1099.4 1126.2 1026.3 1199.6 769.69 321.03 1174.6 1074 TRUE FALSE FALSE 911.5852044 1017.457751 1140.144731 1121.540083 1014.062043 950.7894377 791.2854299 418.9105692 1045.749319 1111.32142 0.820271425 0.915538685 1.025936071 1.009195056 0.912483125 0.855548557 0.712022117 0.376948164 0.940996277 1 10.11806042 -4.229069619 1.378540336 0.928808142 0.113742558 0.899816571 0.058236806 0.415910082 0.648984953 0.011756123 0.479461262 5.90E-05 4.229069619 -0.815065584 down GAPAT(ph)PHLADAPK ddPTM_HeLa_Curcumin_4h_R1 1 GAPATPHLADAPK 13 0 Q99958 Q99958 FOXC2 Forkhead box protein C2 1 0 GAPAT(1)PHLADAPK 115.34 0.0085128 15156000 4677.9 3224.6 3986.1 4422.2 4434.2 7219.9 6857.7 6878.7 5239.4 3325.8 TRUE FALSE FALSE 4307.639279 3503.320055 4133.828373 4403.902108 4381.325061 5722.411355 7050.108605 8975.983964 4664.650928 3441.371302 1.251721741 1.018001183 1.201215449 1.279693971 1.273133491 1.662828812 2.04863352 2.608257923 1.355462843 1 11.74876784 -4.104785526 0.697247751 1.11021304 3.887276111 0.949638129 0.1076445 0.44384536 0.129810471 0.016826096 1.019334468 7.86E-05 4.104785526 2.777063071 up HDS(ph)VDSGVSK ddPTM_HeLa_Curcumin_4h_R1 1 HDSVDSGVSK 10 0 Q9HC44 Q9HC44 GPBP1L1 Vasculin-like protein 1 1 0 HDS(1)VDSGVSK 96.067 0.015187 6704800 1761.1 1580 1441.2 1550.2 1534.5 2471.9 2139.6 3384.8 1599.9 1775.2 TRUE FALSE FALSE 1621.707077 1716.56816 1494.61214 1543.785683 1516.20209 1959.200076 2199.631418 4416.809938 1424.394973 1836.888068 0.882855687 0.934497964 0.813665332 0.840435359 0.825418879 1.066586533 1.197477111 2.404506848 0.775439178 1 10.843048 -4.102740574 1.794153453 0.920709261 3.386773849 0.965219759 0.085874252 0.173399741 0.396652278 0.011935012 0.821831153 7.89E-05 4.102740574 2.466064589 up SDSDLLTCS(ph)PTEDATMGSR ddPTM_HeLa_Curcumin_4h_R1 2 SDSDLLTCSPTEDATMGSR 19 0 A0A3B3ISP1;Q92625 A0A3B3ISP1 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 0 SDSDLLT(0.041)CS(0.948)PT(0.009)EDAT(0.002)MGSR;S(0.231)DS(0.003)DLLT(0.005)CS(0.438)PT(0.323)EDATMGSR ; 104.16 0.0007112 6663900 2829 2899.4 2463.6 3462.9 2978.6 4640.9 3187.2 3253.3 3475.4 2945.1 TRUE FALSE FALSE 2605.081665 3150.011217 2554.903183 3448.571437 2943.08214 3678.325026 3276.624254 4245.216194 3094.157315 3047.442006 0.854842081 1.033657477 0.83837631 1.131628241 0.96575493 1.207020517 1.075204794 1.393042488 1.015329351 1 11.57338305 -2.15807783 0.454680332 0.9330779 4.2416252 0.617019838 0.096578401 11.55335569 0.349578687 0.019896631 31.16811895 0.006948998 2.15807783 3.3085473 SDSDS(ph)STLSK ddPTM_HeLa_Curcumin_4h_R1 1 SDSDSSTLSK 10 0 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 0 S(0.031)DS(0.122)DS(0.813)S(0.031)T(0.001)LSK 151.13 0.00071048 146740000 6094 8200 6489.7 4887.3 5450.9 4734.2 3238.5 1300.4 4314.2 4883.2 TRUE FALSE FALSE 5611.65347 8908.771462 6730.213991 4867.077648 5385.901578 3752.273555 3329.363594 1696.885974 3840.943054 5052.890837 1.110582764 1.763103884 1.331953175 0.96322636 1.065904994 0.742599371 0.658902735 0.335824784 0.760147642 1 12.3028933 -4.815565235 1.137493294 1.13125801 0.311853673 0.538430412 0.252796288 0.471317867 0.860871243 0.03839777 0.362894818 1.53E-05 4.815565235 -0.819404337 SDSDT(ph)EGLLFSR ddPTM_HeLa_Curcumin_4h_R1 1 SDSDTEGLLFSR 12 0 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 SDS(0.131)DT(0.869)EGLLFSR 212.1 1.76E-09 6863600 1107 1024.5 1014.7 913.33 1499.5 1371.8 1003.8 546.64 1202.1 1021.6 TRUE FALSE FALSE 1019.379782 1113.053215 1052.305675 909.5508825 1481.619442 1087.273217 1031.963926 713.3080196 1070.232638 1057.100524 0.964316788 1.052930341 0.99546415 0.860420425 1.401588031 1.028542879 0.976221185 0.674777851 1.012422767 1 10.04589686 -4.26380054 3.819051902 1.012036264 0.641782969 0.385690954 0.133942206 0.209215746 5.920432821 0.017982131 0.215896527 5.45E-05 4.26380054 -0.370253295 SDSDYDLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 SDSDYDLSPK 10 0 A0A1B0GW84;A0A087WSZ7;Q08499-2;Q08499-10;Q08499-9;Q08499-11;Q08499;A0A1W2PQN6;E9PMG3;Q07343-3;Q07343;Q08499-6;Q08499-7;Q08499-12 A0A1B0GW84;Q08499-6 PDE4D;PDE4B "cAMP-specific 3,5-cyclic phosphodiesterase 4D;cAMP-specific 3,5-cyclic phosphodiesterase 4B" 1 0 SDS(0.005)DYDLS(0.995)PK;SDSDYDLS(1)PK;SDS(0.105)DYDLS(0.895)PK ;; 123.01 0.0040457 677849000 14564.7 14005.7 14710 14699.7 14611 12262 9665.6 9754.7 16483.7 14430.3 TRUE FALSE FALSE 13411.88863 15216.2903 15255.16554 14638.87654 14436.77337 9718.722979 9936.790722 12728.86312 14675.47935 14931.75185 0.898212665 1.019055932 1.02165946 0.980385737 0.966850609 0.650876272 0.665480569 0.852469506 0.982837077 1 13.86609582 -5.270637821 24.98589282 0.964476626 0.717195961 0.784772467 0.061537925 229.8371151 624310.9846 0.009505904 0.021532103 5.36E-06 5.270637821 -0.247280666 GISS(ph)DNESVASCNSVK ddPTM_HeLa_Curcumin_4h_R1 1 GISSDNESVASCNSVK 16 0 A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-11;Q8IVL1;A0A0A0MTL4;Q8IVL1-4;Q8IVL1-3;Q8IVL1-2;Q8IVL1-5;E9PNV5 A0A0A0MTE8 NAV2 Neuron navigator 2 1 0 GIS(0.001)S(0.999)DNESVASCNSVK 281.07 1.69E-65 33619000 3127.5 2628.5 2443.3 2657.7 2464.6 2837.7 2336.5 484.69 2634.4 2691.2 TRUE FALSE FALSE 2879.955075 2855.695828 2533.850847 2646.703142 2435.211255 2249.129033 2402.055902 632.4697498 2345.412911 2784.719 1.034199528 1.025487968 0.909912579 0.950438138 0.874490839 0.807668218 0.862584664 0.227121569 0.842244015 1 11.44331604 -4.228381384 1.401383893 0.99195724 2.19E-85 0.824511825 0.092860292 0.342709713 0.555750862 0.012017626 0.487325695 5.91E-05 4.228381384 -0.99195724 down SDSKEDENLVINEVINS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SDSKEDENLVINEVINSPK 19 1 Q5FWF5-2;Q5FWF5 Q5FWF5-2 ESCO1 N-acetyltransferase ESCO1 1 0 SDSKEDENLVINEVINS(1)PK 102.78 0.00033502 3435500 2638.9 2327.3 2557.7 3236.2 2917.2 2800.4 2212.9 1102.5 3539.5 3030.5 TRUE FALSE FALSE 2430.02828 2528.461442 2652.490612 3222.809462 2882.414295 2219.565473 2274.988018 1438.647175 3151.225705 3135.809649 0.774928504 0.806318535 0.845871054 1.027743971 0.919193005 0.707812566 0.725486644 0.458780135 1.004916133 1 11.61462227 -4.255497161 1.063418172 0.89133397 0.253004722 0.695963306 0.091267568 0.929336359 0.812655339 0.016239126 0.67073081 5.55E-05 4.255497161 -0.638329248 SDSPES(ph)DAER ddPTM_HeLa_Curcumin_4h_R1 2 SDSPESDAER 10 0 O75400-2;O75400-3;O75400 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 0 SDS(0.003)PES(0.997)DAER;SDSPES(1)DAER ; 134.38 0.0022999 5544800 2534.1 2358.9 2494 2589.3 3120 2809.2 2314.5 1801.49 2205.63 2013.67 TRUE FALSE FALSE 2333.523311 2562.792805 2586.429834 2578.586163 3082.796038 2226.540254 2379.438641 2350.756008 1963.677907 2083.644883 1.119923712 1.229956614 1.241300692 1.237536292 1.479520845 1.068579523 1.141959775 1.12819417 0.942424462 1 11.0248937 -7.869907106 0.973497924 1.025632755 1.221541426 0.426219434 0.108147232 0.364798761 0.73445038 0.029009582 0.024703455 1.35E-08 7.869907106 0.195908671 EAPS(ph)PTLR ddPTM_HeLa_Curcumin_4h_R1 2 EAPSPTLR 8 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 EAPS(0.996)PT(0.004)LR;EAPS(0.999)PT(0.001)LR ; 154.01 0.0015269 210810000 8806.3 6927.6 7698.2 8653 8207.6 8708.2 5738.7 2230.24 8900.2 7466.4 TRUE FALSE FALSE 8109.272063 7526.390875 7983.502064 8617.196179 8109.729731 6902.021158 5899.712477 2910.229909 7923.870327 7725.856844 1.049627533 0.974182026 1.033348433 1.115370936 1.049686772 0.893366431 0.763632125 0.376687009 1.02562997 1 12.91547923 -4.228161317 1.260446978 1.029136721 0.049686994 0.959829253 0.041310093 0.218508315 0.274909221 0.006610191 0.281872691 5.91E-05 4.228161317 -0.979449727 down T(ph)SPTVATQTGASATSTR ddPTM_HeLa_Curcumin_4h_R1 4 TSPTVATQTGASATSTR 17 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 0 T(0.843)S(0.157)PTVATQTGASATSTR;T(0.836)S(0.163)PTVATQTGASATSTR;T(0.985)S(0.015)PTVATQTGASATSTR;T(0.863)S(0.137)PTVATQTGASATSTR ;;; 262.82 1.58E-51 236959000 9712.8 7242.5 7090.1 8599.7 7392.7 8193.4 5108.99 2558.8 9782.3 7597.8 TRUE FALSE FALSE 8944.021631 7868.509428 7352.865343 8564.11672 7304.546881 6493.996481 5252.334509 3338.966341 8709.206164 7861.822984 1.13765238 1.000850495 0.935262134 1.08932963 0.929116173 0.826016624 0.668080993 0.424706375 1.107784566 1 12.94064817 -4.227535296 0.718888655 1.05845761 1.16E-09 0.925944399 0.057180892 0.601513344 0.209872623 0.0113006 0.520576173 5.92E-05 4.227535296 -1.058457609 down SDSQAS(ph)LTVPLSPQVVR ddPTM_HeLa_Curcumin_4h_R1 2 SDSQASLTVPLSPQVVR 17 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 0 SDS(0.132)QAS(0.83)LT(0.038)VPLSPQVVR;S(0.058)DS(0.411)QAS(0.513)LT(0.018)VPLSPQVVR ; 179.07 9.18E-06 8476600 1040.23 885.37 908.55 830.1 1082.12 1942.49 1410.88 1672.03 1353.02 1123.09 TRUE FALSE FALSE 957.8946979 961.8974377 942.2216622 826.6652661 1069.216426 1539.595678 1450.465496 2181.82425 1204.597091 1162.117294 0.824266796 0.827711146 0.810780174 0.711344088 0.920058957 1.324819522 1.248123148 1.877456141 1.036553795 1 10.18253997 -4.15370466 0.934371283 0.885406342 2.512825224 0.850980048 0.127486798 0.685990044 0.394719247 0.020643062 1.182534374 7.02E-05 4.15370466 1.627418882 SDSQASLTVPLS(ph)PQVVR ddPTM_HeLa_Curcumin_4h_R1 2 SDSQASLTVPLSPQVVR 17 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 0 SDSQASLTVPLS(1)PQVVR;SDSQASLTVPLS(1)PQVVR ; 288.92 8.83E-80 115856000 5624.8 4784 4559.6 5298.9 4638.2 3744.3 2607.6 1679.06 4614.4 4322.7 TRUE FALSE FALSE 5179.591145 5197.507643 4728.582787 5276.974556 4582.892494 2967.689973 2680.762238 2190.997665 4108.211865 4472.913503 1.157990455 1.16199601 1.057159452 1.179762263 1.024587775 0.663480296 0.599332457 0.489836806 0.918464411 1 12.12699914 -5.208349155 2.586933154 1.090067504 0.550918555 0.890266417 0.07924161 0.05965637 0.777481871 0.010883287 0.031986288 6.19E-06 5.208349155 -0.539148948 SDTDTGVCS(ph)GTDEDPDDKNAPFR ddPTM_HeLa_Curcumin_4h_R1 2 SDTDTGVCSGTDEDPDDKNAPFR 23 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83;Q5JSH3-3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 S(0.002)DT(0.002)DT(0.007)GVCS(0.916)GT(0.072)DEDPDDKNAPFR;SDTDTGVCS(0.985)GT(0.015)DEDPDDKNAPFR ; 126.1 2.45E-06 55904000 7877 6366.4 6847.3 7307.8 8441.7 8729.4 7259.6 5935.8 8003.3 6985.9 TRUE FALSE FALSE 7253.527138 6916.683248 7101.066961 7277.56226 8341.038241 6918.824039 7463.284838 7745.598095 7125.358013 7228.659505 1.003440144 0.956841755 0.982349073 1.006765121 1.153884511 0.957137908 1.032457655 1.071512372 0.985709454 1 12.81951242 -5.975634814 24.99999821 0.996205433 1.0497014 0.306092091 0.047025088 251.8909213 258452.5891 0.006528412 0.011833441 1.06E-06 5.975634814 0.053495967 SDTEIS(ph)LEVTDVEESVEKEK ddPTM_HeLa_Curcumin_4h_R1 2 SDTEISLEVTDVEESVEKEK 20 1 P26374 P26374 CHML Rab proteins geranylgeranyltransferase component A 2 1 0 S(0.033)DT(0.123)EIS(0.74)LEVT(0.104)DVEESVEKEK;S(0.006)DT(0.023)EIS(0.969)LEVT(0.002)DVEESVEKEK ; 119.43 5.21E-05 5511600 1368.75 1097.98 1583.57 1629.33 1251.75 1705.48 1051.07 1106.08 1426.16 1157.49 TRUE FALSE FALSE 1260.411993 1192.884499 1642.258497 1622.588264 1236.823699 1351.744223 1080.560195 1443.3187 1269.713816 1197.712691 1.052349201 0.995968822 1.371162307 1.354739142 1.032654749 1.128604742 0.902186479 1.205062542 1.060115523 1 10.22606616 SDTEISLEVTDVEES(ph)VEKEK ddPTM_HeLa_Curcumin_4h_R1 2 SDTEISLEVTDVEESVEKEK 20 1 P26374 P26374 CHML Rab proteins geranylgeranyltransferase component A 2 1 0 SDTEISLEVTDVEES(1)VEKEK;SDTEISLEVTDVEES(1)VEKEK ; 141.36 4.84E-05 13933600 3085.2 2657.9 2986.1 3549.3 3309.2 4007.6 3120 995.87 3333.7 3655.6 TRUE FALSE FALSE 2841.003165 2887.637033 3096.767493 3534.613937 3269.739951 3176.378585 3207.538803 1299.506179 2968.001451 3782.631828 0.751065209 0.763393628 0.818680652 0.934432453 0.864408724 0.839727134 0.847964843 0.34354551 0.784639263 1 11.88517465 -13.52287875 0.032746157 2.153444506 3.70E-18 0.164947475 0.15249928 1059.201901 2.781124433 144.2228943 57.32099262 3.00E-14 13.52287875 -2.153444506 SDTS(ph)SPEVR ddPTM_HeLa_Curcumin_4h_R1 1 SDTSSPEVR 9 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.001)DT(0.062)S(0.469)S(0.469)PEVR 142.98 0.0021818 115080000 7066.1 6278.8 7076.2 6809.8 6720.8 6739.7 5337.1 4160.3 6653.2 6130.7 TRUE FALSE FALSE 6506.810729 6821.511494 7338.450197 6781.622852 6640.658849 5341.810248 5486.844662 5428.756318 5923.360605 6343.741369 1.02570555 1.07531362 1.156801605 1.069025746 1.04680479 0.842059904 0.864922503 0.855765707 0.933732992 1 12.63111824 -5.261674639 24.99847039 1.034763043 0.855316676 0.716732284 0.05442655 8.773690253 932361.5465 0.007686553 0.018272757 5.47E-06 5.261674639 -0.179446367 SDTSGDYEITLLK ddPTM_HeLa_Curcumin_4h_R1 1 SDTSGDYEITLLK 13 0 P12429;D6RA82 P12429 ANXA3 Annexin A3;Annexin 0 0 172.92 0.0017467 3787200 1027.1 757.04 955.83 1035.3 771.01 938.44 940.88 905.9 841.24 997.32 FALSE FALSE TRUE 945.8039512 822.4751643 991.2539006 1031.016203 761.8162093 743.7969656 967.2785606 1182.10474 748.9580767 1031.976796 0.916497304 0.796989979 0.960538943 0.999069172 0.7382106 0.7207497 0.937306502 1.145476085 0.725750889 1 10.01119482 -8.610295004 0.80817046 0.994843653 0.893503811 0 0.146992317 1.103168283 1.459569939 0.057832879 0.026606363 2.45E-09 8.610295004 -0.101339842 SDTSGHFER ddPTM_HeLa_Curcumin_4h_R1 1 SDTSGHFER 9 0 P20073-2;P20073 P20073-2 ANXA7 Annexin A7 0 0 120.27 0.0049208 1876700 1412.6 1429.1 1061.5 843.63 1758.4 3366.1 1369.9 1105 1920.6 1255.9 FALSE FALSE TRUE 1300.791219 1552.625036 1100.840124 840.1392826 1737.432228 2667.932916 1408.335707 1441.909413 1709.914985 1299.542432 1.000960944 1.194747473 0.847098253 0.646488535 1.336956906 2.052978688 1.083716601 1.109551622 1.315782343 1 10.34378802 -5.5579669 16.01008816 0.982141298 1.43435965 0.294746339 0.299871738 3.178621829 1449.948134 0.039782905 0.079577538 2.77E-06 5.5579669 0.452218352 LQELASPPAGRPT(ph)PAPR ddPTM_HeLa_Curcumin_4h_R1 1 LQELASPPAGRPTPAPR 17 1 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 0 LQELAS(0.236)PPAGRPT(0.764)PAPR 140.68 0.003283 12355000 4147 3608.1 3567 3722.4 3821.1 4797.4 3303.8 1039.7 4345.5 3775.7 TRUE FALSE FALSE 3818.760574 3919.968087 3699.196158 3706.997695 3775.535878 3802.365162 3396.495736 1356.699744 3868.809522 3906.905294 0.977438736 1.003343514 0.94683538 0.948832238 0.96637507 0.973242215 0.869357069 0.34725688 0.990249118 1 11.93181057 -4.227237461 2.444064985 0.98183086 0.168837798 0.989565703 0.01926198 0.047573539 0.320210641 0.003175152 0.083559014 5.93E-05 4.227237461 -0.812993062 down SDVEAIFSK ddPTM_HeLa_Curcumin_4h_R1 2 SDVEAIFSK 9 0 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;G3V576;G3V555;G3V575;B7ZW38;A0A0G2JPF8;P0DMR1;B4DSU6;G3V251;G3V3K6;G3V5X6;G3V4M8;G3V2H6;A0A0G2JNQ3;O60812;B2RXH8 P07910;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL1;HNRNPCL2 Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoprotein C-like 1;Heterogeneous nuclear ribonucleoprotein C-like 2 0 0 ; ; 149.82 3.96E-06 5925100 5760 4603.8 4994.7 4894.9 4968.9 5822.9 4647.9 4100 5399.4 4353 FALSE FALSE TRUE 5304.089922 5001.731958 5179.807976 4874.646201 4909.649113 4615.164902 4778.307565 5350.071126 4807.099329 4504.266426 1.177570201 1.110443185 1.149978151 1.082228656 1.089999713 1.024620763 1.060840348 1.187778568 1.067232458 1 12.13707645 -9.561792708 1.353215578 1.000354508 1.11488914 0.221644672 0.052038222 0.356618559 1.176081339 0.036857973 0.008793525 2.74E-10 9.561792708 0.114534633 SDVLELTDDNFESR ddPTM_HeLa_Curcumin_4h_R1 2 SDVLELTDDNFESR 14 0 H7BZJ3 H7BZJ3 PDIA3 0 0 ; ; 222.73 1.78E-13 196062000 11462.3 8791.7 10094.9 9978.6 9644.8 11826.5 8537.9 6159.3 10359.3 9728.6 FALSE FALSE TRUE 10555.04686 9551.615373 10469.02587 9937.311197 9529.792059 9373.550588 8777.450495 8037.242216 9222.910708 10066.66813 1.048514437 0.948835827 1.039969307 0.987149976 0.946667948 0.931147274 0.871932042 0.798401429 0.91618305 1 13.29729864 -4.190260702 0.577260195 1.020675288 0.631356061 0.654925586 0.042464085 0.954554228 0.202831666 0.005412208 0.252074964 6.45E-05 4.190260702 -0.389319226 SDVYYFS(ph)PSGKK ddPTM_HeLa_Curcumin_4h_R1 1 SDVYYFSPSGKK 12 1 Q9UBB5;X6RBL6;Q9UBB5-3 Q9UBB5 MBD2 Methyl-CpG-binding domain protein 2 1 0 S(0.012)DVYYFS(0.886)PS(0.102)GKK 91.032 0.0051416 0 1532.2 1163 1253.9 1195.6 1182.5 2081.7 1797.7 695.66 1466.1 1074.8 TRUE FALSE FALSE 1410.924753 1263.524538 1300.370637 1190.652924 1168.39946 1649.931954 1848.138624 907.7635316 1305.272498 1112.14922 1.268646984 1.136110618 1.169241154 1.070587384 1.050577961 1.483552679 1.661772171 0.816224581 1.173648711 1 10.11913466 -12.88528687 0.251765775 5.54E-09 1.253310449 0.009136411 0.2286331 54.86011767 0.968212094 27.32065193 0.133026665 1.30E-13 12.88528687 1.253310444 SDY(ph)S(ph)STIGS(ph)DK ddPTM_HeLa_Curcumin_4h_R1 1 SDYSSTIGSDK 11 0 G3V1W5;Q7RTY8 G3V1W5 TMPRSS7 Transmembrane protease serine 7 3 0 S(0.036)DY(0.645)S(0.642)S(0.584)T(0.093)IGS(0.999)DK 58.04 0.0095425 0 1631.3 1056.1 1455.2 1565 1435.3 1817.6 1460.9 1273.3 1823.6 1593.4 TRUE FALSE FALSE 1502.180884 1147.384578 1509.130992 1558.524445 1418.184985 1440.609271 1501.888922 1661.523308 1623.555642 1648.770531 0.911091541 0.695903133 0.915306869 0.945264617 0.860146975 0.873747586 0.910914462 1.007734719 0.984706854 1 10.68717491 -8.551076968 1.126471833 0.987623098 0.888207171 0.219765186 0.076057822 0.479035234 1.229978381 0.025436159 0.015066561 2.81E-09 8.551076968 -0.099415927 SEAAAPHTDAGGGLS(ph)S(ph)DEEEGTSSQAEAAR ddPTM_HeLa_Curcumin_4h_R1 2 SEAAAPHTDAGGGLSSDEEEGTSSQAEAAR 30 0 Q01831-2;Q01831 Q01831-2 XPC DNA repair protein complementing XP-C cells 2 0 SEAAAPHT(0.001)DAGGGLS(0.998)S(0.998)DEEEGT(0.001)S(0.001)S(0.001)QAEAAR;SEAAAPHTDAGGGLS(1)S(1)DEEEGTSSQAEAAR ; 114.84 1.34E-10 13513000 3077.2 2097.22 2763.8 3173 3366.7 4386.9 3911.2 3499.6 4369.4 2728.6 TRUE FALSE FALSE 2833.636373 2278.494352 2866.228859 3159.870967 3326.554301 3477.007489 4020.937746 4566.61193 3890.087752 2823.418647 1.00361892 0.806998408 1.015162545 1.119164871 1.178200868 1.231488463 1.424137986 1.617405175 1.377793462 1 11.46322735 -4.52349197 0.69056574 0.985869995 1.874453644 0.622275463 0.140974853 0.474376078 0.193611459 0.012289348 0.305585926 3.00E-05 4.52349197 0.888583649 SEAAS(ph)PALPVITK ddPTM_HeLa_Curcumin_4h_R1 1 SEAASPALPVITK 13 0 Q99958 Q99958 FOXC2 Forkhead box protein C2 1 0 S(0.115)EAAS(0.885)PALPVITK 163.99 0.00017401 229840000 8589.8 6295.2 6281.2 7095.6 6556.4 8147.4 6972.9 1457.3 7658.3 6568.8 TRUE FALSE FALSE 7909.908266 6839.329037 6513.986798 7066.240287 6478.219212 6457.5374 7168.540807 1901.624061 6818.20365 6797.065311 1.163724034 1.006217937 0.958352833 1.039601646 0.953090623 0.950047867 1.054652336 0.279771339 1.003109921 1 12.73069627 -4.26103124 24.95822101 1.045670561 0.279771103 0.914018626 0.066967887 7.949910507 485971.7713 0.011900364 0.093810647 5.48E-05 4.26103124 -0.765899458 DSENLASPS(ph)EYPENGER ddPTM_HeLa_Curcumin_4h_R1 4 DSENLASPSEYPENGER 17 0 A0A3B3ITD8;P52948-6;P52948-2;P52948-5;P52948;P52948-4;P52948-3 A0A3B3ITD8 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 0 DSENLAS(0.082)PS(0.918)EYPENGER;DSENLASPS(0.998)EY(0.002)PENGER;DSENLAS(0.001)PS(0.999)EYPENGER;DSENLAS(0.01)PS(0.99)EYPENGER ;;; 210.57 3.29E-11 638149000 6866.7 5694 6058.5 5861.12 6507 9270.4 9514.3 13268.7 6539.6 6210.9 TRUE FALSE FALSE 6323.193449 6186.163988 6283.03334 5836.868238 6429.408275 7347.614541 9781.245652 17314.26555 5822.222241 6426.728313 0.983889958 0.962568151 0.977641038 0.908217674 1.000417003 1.143290051 1.521963459 2.694102614 0.905938754 1 12.64986877 -4.10269686 1.415380844 0.982306085 3.927699254 0.993963191 0.040686936 0.079443993 0.106373483 0.005274183 0.366982971 7.89E-05 4.10269686 2.945393169 up SEALS(ph)SVLDQEEAMEIK ddPTM_HeLa_Curcumin_4h_R1 1 SEALSSVLDQEEAMEIK 17 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 SEALS(0.92)S(0.08)VLDQEEAMEIK 158.15 1.36E-09 0 839.04 793.28 977.94 803 972.39 1206.9 662.92 574.1 898.52 613.74 TRUE FALSE FALSE 772.6290986 861.8475884 1014.183317 799.6773988 960.7948843 956.5753354 681.519751 749.1404472 799.954604 635.0674193 1.216609568 1.357096211 1.596969528 1.259200794 1.512902182 1.506257928 1.073145512 1.179623493 1.259637291 1 9.310765948 -8.051260743 0.948357012 1.039995144 1.357343737 0.174263623 0.168874828 0.346656449 0.66383451 0.047586119 0.036054397 8.89E-09 8.051260743 0.317348593 SEANDAVNSS(ph)TK ddPTM_HeLa_Curcumin_4h_R1 1 SEANDAVNSSTK 12 0 O15234;J3KSY7;K7EQ38 O15234 CASC3 Protein CASC3 1 0 SEANDAVNS(0.223)S(0.389)T(0.389)K 222.81 8.23E-14 19231000 2996.9 2082.6 2346.5 2582.8 3460.1 3036 1495.5 3410.2 2450.5 2045.6 TRUE FALSE FALSE 2759.692203 2262.610664 2433.463354 2572.113058 3418.840567 2406.299377 1537.459705 4449.954281 2181.686281 2116.684448 1.303780639 1.06894094 1.149658069 1.215161315 1.6151867 1.136824802 0.726352814 2.102322945 1.030709269 1 11.0475905 -1.000000009 0.02959008 4.71E-11 3.06106729 0.153327591 0.332031201 2203.060764 5.051490456 168.8116258 400.6473969 0.099999998 1.000000009 3.06106729 SEANDAVNSST(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SEANDAVNSSTK 12 0 O15234;J3KSY7;K7EQ38 O15234 CASC3 Protein CASC3 1 0 SEANDAVNS(0.195)S(0.195)T(0.609)K 206.67 1.30E-08 14503000 4070.3 3446.4 4229.2 3944.5 5356.4 4684.9 2538.9 5221 3385 3695.2 TRUE FALSE FALSE 3748.13146 3744.291459 4385.937872 3928.178704 5292.528428 3713.19893 2610.134701 6812.858865 3013.673969 3823.607925 0.980260407 0.97925612 1.147067889 1.027348719 1.38417132 0.971124394 0.682636597 1.781788039 0.788175469 1 11.90071888 -6.761016935 24.35619225 0.989561388 1.13853146 0.126055888 0.27627444 17.38087523 1002035.847 0.039177892 0.053473044 1.73E-07 6.761016935 0.148970072 SEAPAEVTHFS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 5 SEAPAEVTHFSPK 13 0 Q6PID6 Q6PID6 TTC33 Tetratricopeptide repeat protein 33 1 0 SEAPAEVTHFS(1)PK;SEAPAEVT(0.004)HFS(0.996)PK;SEAPAEVT(0.024)HFS(0.976)PK;SEAPAEVT(0.092)HFS(0.908)PK;SEAPAEVT(0.023)HFS(0.977)PK ;;;; 156.29 0.00017182 438813000 32175.1 25274.2 27068.1 27090.1 27995 33869.3 24159.7 20940.9 31395.3 26940.7 TRUE FALSE FALSE 29628.40688 27458.78923 28071.2676 26978.00834 27661.17791 26844.42539 24837.55616 27325.68401 27951.31414 27876.88732 1.062830529 0.985001981 1.006972811 0.967755404 0.99226207 0.962963515 0.89097308 0.980227229 1.00266984 1 14.76678186 -5.942009496 0.841526002 1.027786576 0.938332263 0.432332468 0.0308605 0.385744259 0.520809449 0.006208589 0.018633213 1.14E-06 5.942009496 -0.089454313 SECDS(ph)SPEPK ddPTM_HeLa_Curcumin_4h_R1 1 SECDSSPEPK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 SECDS(0.5)S(0.5)PEPK 115.91 0.0052741 87384000 4635.1 4760.7 3947.6 4059.5 4443.3 5368.7 4339.4 3652.6 4062.9 4330.4 TRUE FALSE FALSE 4268.226944 5172.193695 4093.901529 4042.702865 4390.31655 4255.171102 4461.151885 4766.260925 3617.210035 4480.881078 0.952541893 1.15428051 0.913637621 0.902211595 0.979788678 0.949628216 0.995597028 1.063688333 0.807254192 1 12.12956672 -4.297524276 3.616813964 0.97833071 1.070314647 0.08980953 0.084974363 0.386978897 9.033755367 0.008798391 0.089965666 5.04E-05 4.297524276 0.091983938 SECDSS(ph)PEPK ddPTM_HeLa_Curcumin_4h_R1 1 SECDSSPEPK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 SECDS(0.225)S(0.775)PEPK 160.91 0.00060953 110520000 5398.7 5304.4 4603.5 4619.3 5189.8 5596.8 4645.6 4032.5 5135.6 5058.1 TRUE FALSE FALSE 4971.387198 5762.8887 4774.10976 4600.186561 5127.915025 4435.960591 4775.943033 5261.990687 4572.237529 5233.868599 0.949849448 1.101076306 0.912156977 0.878926644 0.979756165 0.847549094 0.912507248 1.005373098 0.87358661 1 12.35366199 SECLNNIGDSSPLIR ddPTM_HeLa_Curcumin_4h_R1 2 SECLNNIGDSSPLIR 15 0 Q92973-2;Q92973;E7EW37 Q92973-2 TNPO1 Transportin-1 0 0 ; ; 182.37 1.80E-07 3325500 1367.97 2150.4 1824.48 1835.63 2238.2 2611.3 1827.37 1387.77 2847.2 1970.58 FALSE FALSE TRUE 1259.693731 2336.270994 1892.096834 1828.034649 2211.510927 2069.686945 1878.641084 1810.894684 2534.869283 2039.057508 0.617782346 1.145760227 0.927927156 0.896509609 1.084575064 1.015021369 0.921328151 0.888103782 1.243157328 1 10.99368675 -7.253495207 24.98954905 0.819508329 0.980116815 0 0.177187232 760.9232908 2393595.15 0.026352986 0.031969023 5.58E-08 7.253495207 0.160608486 SECS(ph)SDFGGK ddPTM_HeLa_Curcumin_4h_R1 1 SECSSDFGGK 10 0 Q14C86-4;Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;F8W9S7;Q14C86-3;H0Y4E7;H0Y7I9;C9IZ08 Q14C86-4 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 0 SECS(0.97)S(0.03)DFGGK 154.15 0.00064829 10525000 1276.3 1047.5 1615.3 1518.7 1838.2 1591.3 1247.1 1039.2 1209.1 1265.7 TRUE FALSE FALSE 1175.279508 1138.041232 1675.164439 1512.416022 1816.280666 1261.246442 1282.09027 1356.047296 1076.464755 1309.682981 0.897377095 0.868944049 1.279061012 1.154795507 1.386809398 0.963016593 0.978931763 1.035401174 0.821927727 1 10.35500192 -6.775825579 24.99952691 0.943990494 1.130800002 0.417245046 0.132005814 214.1744177 372179.5137 0.021565856 0.028413745 1.68E-07 6.775825579 0.186809507 SEDADRCTLPEHES(ph)PSQDISDACEAESTER ddPTM_HeLa_Curcumin_4h_R1 1 SEDADRCTLPEHESPSQDISDACEAESTER 30 1 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 1 0 S(0.001)EDADRCT(0.031)LPEHES(0.741)PS(0.215)QDIS(0.011)DACEAESTER 50.088 0.0060399 26449000 466.68 445.64 380.48 385.35 424.11 755.94 207.67 264.63 676.79 447.11 TRUE FALSE FALSE 429.7417856 484.1591359 394.5809235 383.7555238 419.0527652 599.1495228 213.4966613 345.3144688 602.5478302 462.6470392 0.928876117 1.046497859 0.852876794 0.829477963 0.905772068 1.295046703 0.461467692 0.746388585 1.30239206 1 8.853768148 -4.741804284 24.99999794 0.966846625 0.60392809 0.454509542 0.174748681 132.7804357 169057.3641 0.017635938 0.065798183 1.81E-05 4.741804284 -0.362918535 SEDDSAKFDS(ph)NEEDSASVFSPSFGLK ddPTM_HeLa_Curcumin_4h_R1 2 SEDDSAKFDSNEEDSASVFSPSFGLK 26 1 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 1 0 S(0.001)EDDS(0.001)AKFDS(0.729)NEEDS(0.142)AS(0.113)VFS(0.014)PSFGLK;S(0.002)EDDS(0.007)AKFDS(0.933)NEEDS(0.055)AS(0.004)VFSPSFGLK ; 91.767 5.15E-06 233534000 8685.9 3456 7148.3 8877.1 7910.7 8475.6 6439.2 4737.5 9766.4 6823.6 TRUE FALSE FALSE 7998.40185 3754.72124 7413.222286 8840.368912 7816.370069 6717.66502 6619.866622 6181.941941 8695.050354 7060.719592 1.132802648 0.531776003 1.049924472 1.252049284 1.107021737 0.951413653 0.9375626 0.875539931 1.231468017 1 12.78559951 -5.054874628 4.914530004 1.039353133 0.913722407 0.082984415 0.188915755 0.427044991 22.0077494 0.026012143 0.071072624 8.81E-06 5.054874628 -0.125630726 SEDDSAKFDSNEEDSAS(ph)VFSPSFGLK ddPTM_HeLa_Curcumin_4h_R1 1 SEDDSAKFDSNEEDSASVFSPSFGLK 26 1 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 1 0 SEDDS(0.003)AKFDS(0.174)NEEDS(0.174)AS(0.633)VFS(0.014)PSFGLK 63.979 0.00075854 10148000 3517.4 1631.2 2420.3 3230.5 2774.1 2928 2462.6 1833.2 3175.4 2169 TRUE FALSE FALSE 3238.994078 1772.19366 2509.998447 3217.133047 2741.020669 2320.699795 2531.693928 2392.134241 2827.066564 2244.372589 1.443162376 0.789616514 1.118351944 1.433422001 1.221285932 1.03400826 1.128018557 1.065836507 1.25962444 1 11.13209648 -5.267518471 23.69248329 1.192429662 1.081160855 0.061617383 0.183226908 618.5006612 2410538.813 0.031147472 0.07144312 5.40E-06 5.267518471 -0.111268808 SEDEESLAGQK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 SEDEESLAGQKR 12 1 F8W126;Q96EZ8-3;Q96EZ8;Q96EZ8-2;F8W0I9;F8VVA6;F8VP44 F8W126 MCRS1 Microspherule protein 1 0 1 ; SEDEESLAGQK(1)R;SEDEESLAGQK(1)R 183.03 4.96E-10 4165700 3043.41 2758.58 2746.13 3295.6 3711.9 1697.05 1582.23 1706.1 3293.4 2770.36 FALSE TRUE FALSE 2802.520887 2997.019363 2847.903994 3281.96368 3667.638017 1345.0627 1626.623115 2226.282036 2932.12226 2866.629804 0.977636137 1.045485315 0.993467657 1.144885774 1.279425063 0.469213952 0.567433965 0.776619999 1.022846499 1 11.48513989 -5.250785613 24.99180947 1.022520783 0.600723758 0.763998652 0.115848607 281.0001753 659174.0797 0.016706702 0.042118113 5.61E-06 5.250785613 -0.421797025 SEDES(ph)ET(ph)EDEEEKSQEDQEQK ddPTM_HeLa_Curcumin_4h_R1 2 SEDESETEDEEEKSQEDQEQK 21 1 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 2 0 S(0.004)EDES(0.994)ET(0.987)EDEEEKS(0.016)QEDQEQK;S(0.058)EDES(0.995)ET(0.944)EDEEEKS(0.004)QEDQEQK ; 94.973 0.00050469 407250000 9352.7 7764 8601.6 8280.6 8362.4 9484.9 7951.1 7173.8 8754.3 8059.5 TRUE FALSE FALSE 8612.423926 8435.085564 8920.382863 8246.337071 8262.683842 7517.624823 8174.186467 9361.058596 7793.975192 8339.567025 1.032718353 1.011453657 1.069645802 0.988820768 0.990780914 0.901440662 0.980169167 1.122487363 0.934577919 1 13.02575677 SEDES(ph)ETEDEEEK ddPTM_HeLa_Curcumin_4h_R1 2 SEDESETEDEEEK 13 0 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 0 SEDES(0.988)ET(0.012)EDEEEK;S(0.022)EDES(0.975)ET(0.003)EDEEEK ; 231.26 1.45E-19 7082000 1995.63 1708.13 1905.5 1682.9 1523.56 1640.6 1097.21 1329.09 1397.37 1149.25 TRUE FALSE FALSE 1837.67378 1855.773146 1976.119506 1675.936606 1505.392542 1300.321067 1127.99476 1734.323423 1244.082007 1189.186352 1.545320274 1.560540232 1.661740822 1.40931369 1.265901294 1.093454415 0.948543311 1.458411812 1.046162366 1 10.2157591 -3.913954367 20.09816314 1.290841145 10.44470732 0.044395035 0.242962372 1602.826156 375494.2589 0.038904413 1980.511658 0.000121912 3.913954367 9.153866179 SEDES(ph)ETEDEEEKSQEDQEQK ddPTM_HeLa_Curcumin_4h_R1 2 SEDESETEDEEEKSQEDQEQK 21 1 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 0 S(0.007)EDES(0.585)ET(0.407)EDEEEKS(0.001)QEDQEQK;S(0.003)EDES(0.854)ET(0.142)EDEEEKS(0.001)QEDQEQK ; 73.928 0.0010126 103392000 4071.71 2947.58 3186.6 3223.14 3212.94 2508.36 2412.83 2366.51 3061.67 2485.01 TRUE FALSE FALSE 3749.429857 3202.355681 3304.698199 3209.803501 3174.627789 1988.097861 2480.527516 3088.048005 2725.812461 2571.363913 1.458148276 1.245391858 1.285192727 1.248288305 1.234608518 0.77316861 0.964673846 1.200937755 1.060064835 1 11.32831809 -5.302271552 23.18741106 1.232038267 0.978101453 0.341210492 0.151542254 209.4334228 118930.8494 0.02734024 0.061135862 4.99E-06 5.302271552 -0.253936814 SEDES(ph)ETEDEEEKSQEDQEQKR ddPTM_HeLa_Curcumin_4h_R1 1 SEDESETEDEEEKSQEDQEQKR 22 2 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 0 S(0.036)EDES(0.743)ET(0.221)EDEEEKSQEDQEQKR 46.962 0.011869 13473000 1159.6 919.09 1000.2 995.75 982.21 1200.7 772.72 928.42 1162.2 735.69 TRUE FALSE FALSE 1067.816436 998.5320442 1037.268292 991.6298503 970.4977873 951.6612853 794.4004435 1211.490984 1034.709568 761.2551727 1.402704999 1.311691638 1.362576346 1.302624778 1.274865278 1.250121273 1.04354029 1.591438755 1.359215155 1 9.572236316 -9.383612052 1.063880096 0.996831847 1.312754406 0 0.168950649 0.369754601 0.736742429 0.088622684 0.021861621 4.13E-10 9.383612052 0.315922559 SEDESET(ph)EDEEEKSQEDQEQK ddPTM_HeLa_Curcumin_4h_R1 2 SEDESETEDEEEKSQEDQEQK 21 1 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 1 0 S(0.002)EDES(0.161)ET(0.837)EDEEEKSQEDQEQK;S(0.012)EDES(0.459)ET(0.528)EDEEEKS(0.001)QEDQEQK ; 115.31 1.00E-05 126127000 3989.2 2975.61 3239.11 3123.18 3205.7 2928.26 2243.74 2621.82 3762.2 2648.64 TRUE FALSE FALSE 3673.450611 3232.808469 3359.154266 3110.257109 3167.474121 2320.905868 2306.693306 3421.200849 3349.496073 2740.680043 1.340342745 1.179564349 1.225664512 1.134848673 1.155725613 0.84683576 0.841649981 1.248303631 1.222140498 1 11.4203182 -5.352050706 7.896211258 1.168696699 0.965616679 0.322979059 0.132201759 0.308463441 24.05463983 0.02264766 0.0508103 4.45E-06 5.352050706 -0.20308002 SEDFGVNEDLADSDAR ddPTM_HeLa_Curcumin_4h_R1 2 SEDFGVNEDLADSDAR 16 0 P04083 P04083 ANXA1 Annexin A1 0 0 ; ; 362.15 1.28E-194 281640000 3328.8 2773.7 2863.11 2902.78 3482.6 3563.9 3441.5 3319.6 3087.5 2824.2 FALSE FALSE TRUE 3065.321967 3013.446269 2969.219375 2890.769065 3441.07227 2824.706967 3538.059228 4331.730758 2748.808975 2922.34074 1.048926953 1.031175533 1.016041468 0.989196443 1.177505492 0.966590558 1.210693599 1.482281207 0.940618915 1 11.51290869 -4.386043093 2.377857799 1.028923185 1.530359853 0.837849398 0.062693318 0.101475039 0.823124564 0.007358726 0.092586083 4.11E-05 4.386043093 0.501436668 SEDMPFS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SEDMPFSPK 9 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 SEDMPFS(1)PK 117.25 0.0069472 63927000 6005.5 5514 5777.8 5993.1 6064.6 6311.9 5418.6 4306.2 5939.4 5767.7 TRUE FALSE FALSE 5530.158338 5990.60559 5991.930351 5968.30214 5992.283606 5002.74079 5570.631333 5619.140557 5287.86268 5968.127146 0.926615369 1.003766415 1.003988388 1.000029322 1.004047578 0.838242998 0.933396893 0.941524941 0.886017096 1 12.54306256 -5.285218809 24.9385833 0.975429921 0.907289117 0.33544572 0.045436688 600.5837292 629858.9005 0.005981455 0.013382383 5.19E-06 5.285218809 -0.068140804 SEDPPGQEAGS(ph)EEEGSSASGLAK ddPTM_HeLa_Curcumin_4h_R1 1 SEDPPGQEAGSEEEGSSASGLAK 23 0 K7EIG1;I3L2B0;A0A494C0R8;O75153 K7EIG1 CLUH Clustered mitochondria protein homolog 1 0 SEDPPGQEAGS(0.999)EEEGS(0.001)SASGLAK 94.834 6.04E-05 10659000 1634.1 1288.8 1364.3 1681.6 1557.3 1378.8 1328.2 1246.9 1568.5 1621.1 TRUE FALSE FALSE 1504.759261 1400.198129 1414.862158 1674.641985 1538.730215 1092.821338 1365.465717 1627.07407 1396.439474 1677.433104 0.897060668 0.834726658 0.843468604 0.998336077 0.917312417 0.651484304 0.814020967 0.969978514 0.83248594 1 10.71203952 -9.025084642 0.289697962 1.059957669 0.835259421 0 0.10479601 3.867049817 0.504640325 0.304640649 0.065993118 9.44E-10 9.025084642 -0.224698249 SEDVTPMEVTAEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 SEDVTPMEVTAEKR 14 1 O94916-2;O94916;O94916-4;O94916-5 O94916-2 NFAT5 Nuclear factor of activated T-cells 5 0 1 SEDVTPMEVTAEK(1)R 150.51 0.0003357 1928100 998.56 756.27 974.86 697.86 615.77 638.91 288.67 485.91 605.79 643.83 FALSE TRUE FALSE 919.5229223 821.6386089 1010.989169 694.9724402 608.4273449 506.392864 296.7693033 634.0617221 539.3363526 666.2030446 1.380244251 1.233315602 1.517539101 1.043184125 0.91327614 0.760117907 0.445463745 0.951754465 0.809567529 1 9.379818137 -5.633344141 2.043318366 1.212210341 0.694560532 0.461210801 0.217697284 0.183199157 1.542643013 0.030924661 0.073365993 2.33E-06 5.633344141 -0.517649809 SEEAHAEDSVMDHHFR ddPTM_HeLa_Curcumin_4h_R1 3 SEEAHAEDSVMDHHFR 16 0 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 0 ;; ;; 121.42 0.00022499 37888500 10439.1 9371.7 8061.7 7974.7 13993.2 18253 10379.5 9193.9 11934.9 8810.1 FALSE FALSE TRUE 9612.83422 10181.74799 8360.473694 7941.702804 13826.34023 14467.12205 10670.72084 11997.07779 10625.67133 9116.250319 1.054472385 1.116878939 0.91709567 0.871158922 1.516669655 1.586959719 1.170516436 1.316010132 1.165574766 1 13.15422482 -5.759402629 24.99999978 1.015205791 1.394853164 0.662470531 0.13167537 23.65787849 290380.1656 0.018417498 0.035415938 1.74E-06 5.759402629 0.379647374 SEEEFIHINNK ddPTM_HeLa_Curcumin_4h_R1 2 SEEEFIHINNK 11 0 Q15046;Q15046-2;H3BVA8;J3KRL2 Q15046 KARS Lysine--tRNA ligase 0 0 ; ; 131.12 0.0021375 11799200 9644.2 8720.6 9765.5 9694.7 11341 11602.5 10082.4 8645.3 9460.2 8869.6 FALSE FALSE TRUE 8880.851393 9474.369806 10127.41802 9654.5859 11205.76598 9196.010713 10365.28501 11281.21217 8422.439728 9177.81794 0.967643012 1.032311805 1.103466868 1.051947856 1.220961895 1.001982255 1.129384466 1.229182388 0.917695228 1 13.16393547 -6.731435363 1.440306483 0.984135215 1.127970352 0.536252363 0.067247609 0.229237875 0.961690021 0.010756526 0.016106161 1.86E-07 6.731435363 0.143835137 SEEEQS(ph)SS(ph)SVKKDETNVK ddPTM_HeLa_Curcumin_4h_R1 1 SEEEQSSSSVKKDETNVK 18 2 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 2 0 S(0.001)EEEQS(0.5)S(0.5)S(0.5)S(0.5)VKKDETNVK 65.231 0.014262 11949000 2929 2759.7 2398.3 2404.8 2725.1 3352.8 3027.6 2245.5 2721.8 2558.5 TRUE FALSE FALSE 2697.166559 2998.236171 2487.183108 2394.849575 2692.604962 2657.391486 3112.546308 2930.142613 2423.22535 2647.407685 1.01879532 1.132517741 0.939478692 0.904601731 1.017072277 1.003771161 1.17569588 1.106796898 0.915320056 1 11.37036466 -4.769926767 24.98572647 1.005791259 1.141246392 0.451675502 0.064489414 104.1525634 306615.1797 0.008027042 0.02465767 1.70E-05 4.769926767 0.135455133 SEEEQSS(ph)S(ph)SMKK ddPTM_HeLa_Curcumin_4h_R1 1 SEEEQSSSSMKK 12 1 A0A0G2JNQ3;O60812;B2RXH8 A0A0G2JNQ3 HNRNPCL1;HNRNPCL2 Heterogeneous nuclear ribonucleoprotein C-like 1;Heterogeneous nuclear ribonucleoprotein C-like 2 2 0 SEEEQS(0.07)S(0.699)S(0.755)S(0.475)MKK 68.515 0.020284 7911900 1948.4 1598.7 1886 1769.1 1530.5 1822.4 1937.6 2011.3 2178 1721.7 TRUE FALSE FALSE 1794.182084 1736.884504 1955.896819 1761.779933 1512.249787 1444.413697 1991.963841 2624.536111 1939.078849 1781.528947 1.007102403 0.974940378 1.097875408 0.98891457 0.848849405 0.810771949 1.11812039 1.473193077 1.088435219 1 10.79890021 -4.330831658 3.408125159 0.985308094 1.502628771 0.745939912 0.087019705 0.093951776 1.791219227 0.011649969 0.111437348 4.67E-05 4.330831658 0.517320676 SEEIS(ph)ESESEETNAPK ddPTM_HeLa_Curcumin_4h_R1 2 SEEISESESEETNAPK 16 0 P54259 P54259 ATN1 Atrophin-1 1 0 SEEIS(0.499)ES(0.499)ES(0.001)EETNAPK;SEEIS(0.998)ES(0.002)ESEETNAPK ; 266.45 7.51E-52 65572000 6192.5 4209.3 4991.5 5533.4 5742.8 5679.2 3703 3177.88 5894.3 3866.5 TRUE FALSE FALSE 5702.357091 4573.133136 5176.489381 5510.504257 5674.320861 4501.269902 3806.896214 4146.800983 5247.710037 4000.860587 1.425282628 1.143037363 1.293843979 1.377329736 1.418275078 1.125075419 0.951519337 1.036477251 1.311645313 1 11.96609464 -4.985610755 6.50009439 1.235391076 1.002298472 0.420870485 0.129096215 0.171163442 30.61352012 0.02494293 0.073465888 1.03E-05 4.985610755 -0.233092604 SEEKISDS(ph)EGFK ddPTM_HeLa_Curcumin_4h_R1 1 SEEKISDSEGFK 12 1 P23246;P23246-2 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 1 0 SEEKIS(0.019)DS(0.981)EGFK 153.81 0.0036619 7824500 1652.3 1504.1 1708.5 1648.1 1484.1 1759.8 1487.8 1405.8 1655.7 1217.9 TRUE FALSE FALSE 1521.518712 1634.107702 1771.818513 1641.280599 1466.403077 1394.797643 1529.543664 1834.421948 1474.073852 1260.221934 1.207341874 1.296682479 1.405957526 1.302374252 1.16360701 1.106787309 1.213709762 1.455634042 1.169693855 1 10.29946211 -8.582874523 0.746873203 1.010101779 1.267530328 0.270615649 0.110832507 0.41307866 0.468324776 0.053806701 0.023933673 2.61E-09 8.582874523 0.257428549 TSLEASMEAS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 TSLEASMEASPK 12 0 A0A0A0MRP0;Q8IWC1-2;Q8IWC1-4;Q8IWC1;Q8IWC1-3 A0A0A0MRP0 MAP7D3 MAP7 domain-containing protein 3 1 0 TSLEASMEAS(1)PK;TSLEAS(0.026)MEAS(0.974)PK;TSLEASMEAS(1)PK ;; 195.72 2.75E-06 362027000 16175 14200.5 15043 16031.9 15083 18034 11681.1 5967.5 19192.1 15152.6 TRUE FALSE FALSE 14894.73168 15427.92794 15600.50681 15965.56425 14903.14508 14293.54511 12008.84023 7786.963279 17086.77465 15679.15172 0.949970505 0.983977209 0.994984109 1.018267093 0.950507103 0.911627451 0.765911348 0.496644424 1.089776727 1 13.93655989 -4.226317933 1.234659147 0.980578802 0.243993553 0.940219986 0.039372894 0.163451785 0.195292416 0.003606178 0.156086921 5.94E-05 4.226317933 -0.736585249 down VVSS(ph)TSEEEEAFTEK ddPTM_HeLa_Curcumin_4h_R1 1 VVSSTSEEEEAFTEK 15 0 Q8N573-3;Q8N573-2;Q8N573-5;Q8N573-8;Q8N573 Q8N573-3 OXR1 Oxidation resistance protein 1 1 0 VVS(0.009)S(0.973)T(0.007)S(0.01)EEEEAFTEK 98.676 0.0044154 16623000 1984.5 1654.4 1685.1 1623.1 1928.6 3063.7 2791.3 4172.2 1801.8 2422.3 TRUE FALSE FALSE 1827.424731 1797.398964 1747.551288 1616.384042 1905.602705 2428.254085 2869.616366 5444.284574 1604.147048 2506.474745 0.729081645 0.717102364 0.6972148 0.644883435 0.760272055 0.96879256 1.14488142 2.172088342 0.640001281 1 11.29144398 -4.093935722 1.60097131 0.822362584 3.134308901 0.923293909 0.121559433 0.376080912 0.652032682 0.021053042 1.527445451 8.05E-05 4.093935722 2.311946318 up RPEGPGAQAPSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 RPEGPGAQAPSSPR 14 1 P40222 P40222 TXLNA Alpha-taxilin 1 0 RPEGPGAQAPS(0.015)S(0.985)PR;RPEGPGAQAPS(0.248)S(0.752)PR;RPEGPGAQAPS(0.057)S(0.943)PR;RPEGPGAQAPS(0.017)S(0.983)PR ;;; 127.2 0.0005576 2941880000 7269.1 6259.8 6410.1 6940 7164.7 9052.2 8892.7 11155.7 6835 6402.5 TRUE FALSE FALSE 6693.743065 6800.869219 6647.663945 6911.284119 7079.265632 7174.671681 9142.205229 14557.02158 6085.2176 6624.986398 1.010378386 1.026548405 1.003423033 1.043214839 1.068570591 1.082971534 1.379958339 2.197290787 0.918525297 1 12.69370178 -4.092215411 1.436079555 1.011719064 3.08191525 0.989791615 0.036417962 0.075518467 0.102447466 0.003422431 0.250138417 8.09E-05 4.092215411 2.070196186 up SEETLDEGPPK ddPTM_HeLa_Curcumin_4h_R1 2 SEETLDEGPPK 11 0 Q00688 Q00688 FKBP3 Peptidyl-prolyl cis-trans isomerase FKBP3 0 0 ; ; 185.14 5.74E-12 3429300 2578.92 2318.16 2119.74 2329.01 2512.2 2994.2 2656.13 2513.08 2457.63 2211.68 FALSE FALSE TRUE 2374.795761 2518.531421 2198.299429 2319.373174 2482.243656 2373.169168 2730.653859 3279.306523 2188.034138 2288.535715 1.037692243 1.100499068 0.960570296 1.013474755 1.084642743 1.036981487 1.193188221 1.432927833 0.956084768 1 11.16020909 -4.185532062 1.337153519 1.022343589 1.668536721 0.895065771 0.043685704 0.299353441 0.405323406 0.005574755 0.274059174 6.52E-05 4.185532062 0.646193132 SEETLLT(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 SEETLLTPER 10 0 Q6P4F7-3;Q6P4F7;H3BQ41 Q6P4F7-3 ARHGAP11A Rho GTPase-activating protein 11A 1 0 SEETLLT(1)PER 115.91 0.015289 29782000 1969.5 1733 1480.8 1888.7 1903.9 2632.3 2026.2 1211.3 2256.8 1476.3 TRUE FALSE FALSE 1813.611997 1882.792798 1535.679751 1880.88506 1881.197236 2086.331308 2083.049719 1580.619794 2009.234686 1527.601315 1.187228617 1.232515827 1.005288314 1.231266981 1.231471338 1.365756423 1.363608226 1.034707013 1.31528735 1 10.57705235 -10.98020351 0.1869208 0.659540977 1.280204442 0 0.147719238 16.49441874 0.459906994 2.497844046 0.169807086 1.05E-11 10.98020351 0.620663465 SEEWADNHLPLTDAELAR ddPTM_HeLa_Curcumin_4h_R1 2 SEEWADNHLPLTDAELAR 18 0 O60664-4;O60664-3;O60664;K7ERZ3;O60664-2 O60664-4 PLIN3 Perilipin-3 0 0 ; ; 93.381 0.0018387 18656300 6657.5 5190.3 5615.5 5425.4 5173.4 7672.9 6324.3 5865.5 6487.2 5609.5 FALSE FALSE TRUE 6130.55185 5638.926404 5823.61537 5402.951132 5111.710584 6081.454049 6501.742837 7653.863949 5775.57039 5804.429707 1.056185045 0.971486725 1.003305348 0.930832382 0.880656816 1.047726367 1.12013465 1.318624625 0.995028053 1 12.50293861 -4.357614526 1.944165791 1.004926172 1.37560047 0.80180199 0.050909654 0.245998712 1.133062667 0.008437074 0.151402558 4.39E-05 4.357614526 0.370674298 SEGDNYSATLLEPAAS(ph)SLSPDHK ddPTM_HeLa_Curcumin_4h_R1 1 SEGDNYSATLLEPAASSLSPDHK 23 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 SEGDNYSATLLEPAAS(0.489)S(0.489)LS(0.023)PDHK 175.33 5.22E-10 24638000 4030.3 3273.1 3020.5 3417.5 4007 4187.5 3352.9 3605.3 3191 2743.1 TRUE FALSE FALSE 3711.297502 3556.012179 3132.442387 3403.359291 3959.219142 3318.965297 3446.97335 4704.539373 2840.955283 2838.422521 1.307521158 1.25281284 1.103585659 1.19903195 1.394866026 1.16929924 1.214397548 1.657448579 1.000892313 1 11.47087365 -13.35119722 0.162351519 5.20E-12 1.369724627 0.444102542 0.138020107 47.0497264 0.533426655 15.21036345 0.260399256 4.45E-14 13.35119722 1.369724627 SEGDNYSATLLEPAASS(ph)LSPDHK ddPTM_HeLa_Curcumin_4h_R1 3 SEGDNYSATLLEPAASSLSPDHK 23 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 SEGDNYSATLLEPAAS(0.048)S(0.899)LS(0.052)PDHK;SEGDNYSATLLEPAAS(0.042)S(0.608)LS(0.349)PDHK;SEGDNYSATLLEPAAS(0.092)S(0.88)LS(0.028)PDHK ;; 170.68 2.23E-09 224601000 11282.2 10573.5 10170 9488.2 13776.9 14404.5 10227.4 10763.5 10900.9 8672.2 TRUE FALSE FALSE 10389.20197 11487.42623 10546.90915 9448.940342 13612.61947 11416.84433 10514.35332 14045.2416 9705.098543 8973.558304 1.157757225 1.280141705 1.175331879 1.052975868 1.516970081 1.272276163 1.171703906 1.565180848 1.081521757 1 13.13146446 -1.000000034 0.081004276 0.755831418 2.503754931 0.44818376 0.132222057 107.2982681 0.638541574 2.102272407 21.08432508 0.099999992 1.000000034 1.747923514 SEGEGEAASADDGSLNT(ph)SGAGPK ddPTM_HeLa_Curcumin_4h_R1 2 SEGEGEAASADDGSLNTSGAGPK 23 0 M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8;M0R2I2 M0QXG9 BABAM1 BRISC and BRCA1-A complex member 1 1 0 SEGEGEAASADDGSLNT(0.5)S(0.5)GAGPK;SEGEGEAASADDGSLNT(0.5)S(0.5)GAGPK ; 153.06 9.21E-07 26207000 7185.1 5524.6 5695.7 5750.4 6507.2 9957.4 7260.2 3139.6 6546.4 5955.8 TRUE FALSE FALSE 6616.391753 6002.121807 5906.787652 5726.606368 6429.60589 7892.122997 7463.901672 4096.849587 5828.276298 6162.763607 1.07360791 0.97393348 0.958464097 0.929227005 1.043299127 1.280614267 1.211128992 0.664774742 0.945724462 1 12.58936174 -5.515848321 24.90768171 1.016294796 1.083716355 0.003682816 0.158671043 928.170943 3288358.349 0.021761346 0.044910172 3.05E-06 5.515848321 0.067421559 SEGETIMSS(ph)SMGKR ddPTM_HeLa_Curcumin_4h_R1 1 SEGETIMSSSMGKR 14 1 B0YIW6;P48444;P48444-2 B0YIW6 ARCN1 Coatomer subunit delta 1 0 SEGET(0.001)IMS(0.03)S(0.485)S(0.485)MGKR 81.972 0.0037478 0 1197 1239.3 1433.9 1471.2 1083.8 1330.1 909.07 569.28 1578.2 1180.8 TRUE FALSE FALSE 1102.256187 1346.41957 1487.041595 1465.112564 1070.876393 1054.222267 934.5760576 742.8508514 1405.075408 1221.832712 0.902133472 1.101967198 1.217058261 1.199110606 0.87645091 0.862820463 0.764896903 0.607980818 1.149973638 1 10.25483106 -4.754320326 1.383088382 0.999333615 0.603824121 0.602208385 0.120029108 0.39254035 1.146956697 0.019401378 0.167838113 1.76E-05 4.754320326 -0.395509494 SEGFDTYR ddPTM_HeLa_Curcumin_4h_R1 1 SEGFDTYR 8 0 P12004 P12004 PCNA Proliferating cell nuclear antigen 0 0 97.798 0.015431 3045000 4201.5 3340.7 3818.2 3961.1 4296.2 5307.1 4300.2 4148 5152.9 4058.6 FALSE FALSE TRUE 3868.946842 3629.455222 3959.705851 3944.710018 4244.970621 4206.347637 4420.852039 5412.706105 4587.639762 4199.636048 0.921257651 0.864230895 0.942868812 0.939298066 1.010794881 1.001598136 1.052675039 1.288851235 1.092389843 1 12.03604859 -2.11250124 0.846585444 0.952374059 14.69267488 0.731719673 0.05794376 22.28092195 0.487071446 0.00724891 555.5384909 0.007717893 2.11250124 13.74030082 SEGGGTGESSQGGTSK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 SEGGGTGESSQGGTSKR 17 1 F5H0R1;Q9H6E5 F5H0R1 TUT1 Speckle targeted PIP5K1A-regulated poly(A) polymerase 0 1 ; SEGGGTGESSQGGTSK(1)R;SEGGGTGESSQGGTSK(1)R 258.91 2.96E-62 1203690 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 SEGS(ph)PVLPHEPAK ddPTM_HeLa_Curcumin_4h_R1 2 SEGSPVLPHEPAK 13 0 Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3;Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5 Q9UKE5-8 TNIK TRAF2 and NCK-interacting protein kinase 1 0 S(0.291)EGS(0.709)PVLPHEPAK;S(0.062)EGS(0.938)PVLPHEPAK ; 139.77 0.0010035 26954000 7781.5 5554.3 6657.7 6932.9 7281.7 7656.2 6249.5 6083.6 7097.3 6768.4 TRUE FALSE FALSE 7165.586064 6034.388943 6904.440219 6904.213497 7194.870483 6068.217817 6424.84415 7938.461635 6318.743947 7003.601396 1.023128767 0.861612276 0.985841402 0.98580903 1.027310105 0.866442488 0.917362909 1.133482788 0.902213531 1 12.77388126 SEGVVAVLLTK ddPTM_HeLa_Curcumin_4h_R1 1 SEGVVAVLLTK 11 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 0 120.06 0.0020952 568450 469.85 501.82 457.47 882.72 589.39 578.7 306.11 267.17 555.66 498.24 FALSE FALSE TRUE 432.6608767 545.1950847 474.4242406 879.0675385 582.3619092 458.6710967 314.6986227 348.6289031 494.7054882 515.5538029 0.83921576 1.057494061 0.920222561 1.705093695 1.129585129 0.88966679 0.610408886 0.676222154 0.959561321 1 9.009979184 -4.891843397 4.105527634 1.004553178 0.64466827 0.326288712 0.234377498 0.234151271 7.125048988 0.035875639 0.118321264 1.28E-05 4.891843397 -0.359884908 SEIDLFNIR ddPTM_HeLa_Curcumin_4h_R1 2 SEIDLFNIR 9 0 P08758;D6RBE9;D6RBL5 P08758 ANXA5 Annexin A5;Annexin 0 0 ; ; 120.87 0.0012865 3094800 1606.36 1446.33 1672.13 1491.02 1835.97 1748.76 1365.56 1312.34 1326.14 1387.87 FALSE FALSE TRUE 1479.214911 1571.34432 1734.100609 1484.850554 1814.077257 1386.047463 1403.873938 1712.466425 1180.66576 1436.098379 1.030023383 1.094175958 1.207508228 1.033947657 1.263198457 0.96514799 0.977561119 1.192443672 0.822134317 1 10.48793887 -7.325907603 3.424379041 1.012858732 1.102188583 0.242189437 0.109868466 0.324340332 7.340826654 0.015570115 0.017945461 4.72E-08 7.325907603 0.089329851 SEIDLFNIRK ddPTM_HeLa_Curcumin_4h_R1 2 SEIDLFNIRK 10 1 P08758;D6RBE9;D6RBL5 P08758 ANXA5 Annexin A5;Annexin 0 0 ; ; 112.36 0.0037365 16027000 6382.6 4906.6 4504.3 5493.5 5008.3 6858.1 5283.3 5413 7270.8 6458.9 FALSE FALSE TRUE 5877.410475 5330.704641 4671.23332 5470.769353 4948.579294 5435.652753 5431.535179 7063.398782 6473.211431 6683.346294 0.879411333 0.79761012 0.698936298 0.818567393 0.740434369 0.813313049 0.812696954 1.056865599 0.968558435 1 12.70635491 -8.179607391 0.93396751 0.980302341 0.814540484 0.32778081 0.090099559 0.378165623 0.698505084 0.028333559 0.01967143 6.61E-09 8.179607391 -0.165761856 SEIDLLDIR ddPTM_HeLa_Curcumin_4h_R1 3 SEIDLLDIR 9 0 P12429;D6RA82 P12429 ANXA3 Annexin A3;Annexin 0 0 ;; ;; 159.28 0.007278 17994300 16662.2 13082 14303.5 14068.4 13983.5 17846.4 15908.7 16758.6 14269.1 14289.5 FALSE FALSE TRUE 15343.36929 14212.74979 14833.60029 14010.18869 13816.7559 14144.85547 16355.05531 21868.21999 12703.81543 14786.05906 1.0376916 0.961226364 1.003215274 0.947526899 0.934444793 0.956634585 1.106113214 1.478975561 0.859175212 1 13.85194996 -4.286152027 2.81846808 0.999076871 1.552045185 0.879884254 0.056339038 0.073525679 0.829367276 0.005887878 0.090494866 5.17E-05 4.286152027 0.552968314 SEIDLVQIK ddPTM_HeLa_Curcumin_4h_R1 2 SEIDLVQIK 9 0 P20073-2;P20073 P20073-2 ANXA7 Annexin A7 0 0 ; ; 110.87 0.0033371 2494900 1027.55 982.81 853.83 767.25 1023.07 1321.59 838.39 909.11 1414.79 813.4 FALSE FALSE TRUE 946.2183332 1067.759717 885.4736909 764.0753228 1010.870558 1047.477337 861.912967 1186.293454 1259.591077 841.6655895 1.124221241 1.26862703 1.052049296 0.907813427 1.201035864 1.244529121 1.024056321 1.409459373 1.496545769 1 9.717103325 SEIDMNDIK ddPTM_HeLa_Curcumin_4h_R1 1 SEIDMNDIK 9 0 P04083 P04083 ANXA1 Annexin A1 0 0 131.5 0.00053583 6334900 5124.2 3913.7 4549.7 4894.5 4416 6293.7 4780.6 5190.1 5287.5 4660.8 FALSE FALSE TRUE 4718.614163 4251.982789 4718.315884 4874.247856 4363.342084 4988.315675 4914.73077 6772.537598 4707.474479 4822.762453 0.978404848 0.881648812 0.978343 1.0106755 0.904739167 1.034327468 1.019069634 1.404285959 0.976095034 1 12.23564404 -4.195925722 2.623755755 0.978976761 1.536654813 0.893373544 0.044554377 0.146073014 1.10159776 0.006120366 0.190598063 6.37E-05 4.195925722 0.557678052 SEIPS(ph)PQSQLLEDAEANLVGR ddPTM_HeLa_Curcumin_4h_R1 1 SEIPSPQSQLLEDAEANLVGR 21 0 Q9ULJ8;Q9ULJ8-4;Q9ULJ8-5;Q9ULJ8-3 Q9ULJ8 PPP1R9A Neurabin-1 1 0 S(0.001)EIPS(0.838)PQS(0.16)QLLEDAEANLVGR 63.16 0.0078933 2325600 1018.9 803.22 823.06 884.4 794.84 1095.1 826.32 671.9 1020.9 967.1 TRUE FALSE FALSE 938.2529899 872.6467577 853.5633276 880.7405871 785.3620521 867.9639157 849.5043153 876.759217 908.9098242 1000.706653 0.937590439 0.872030535 0.85296058 0.880118649 0.784807466 0.867350999 0.848904434 0.87614009 0.908267994 1 9.966803409 -7.519080591 0.811535738 0.987056178 0.845609341 0.551168761 0.036347098 0.149381115 0.206589035 0.007103791 0.007224725 3.03E-08 7.519080591 -0.141446837 SEIS(ph)PEGEK ddPTM_HeLa_Curcumin_4h_R1 1 SEISPEGEK 9 0 Q96PY6-4;Q96PY6-2;Q96PY6-6;Q96PY6;Q96PY6-3 Q96PY6-4 NEK1 Serine/threonine-protein kinase Nek1 1 0 S(0.001)EIS(0.999)PEGEK 92.611 0.017462 8022500 3447.7 3098.8 2760.9 3465.6 3454.9 3437.8 2863.3 2790.3 3199.6 2828.3 TRUE FALSE FALSE 3174.810907 3366.646464 2863.221383 3451.260265 3413.702574 2724.761528 2943.636492 3641.049625 2848.611885 2926.583214 1.084818259 1.150367585 0.978349554 1.179279731 1.166446441 0.93103846 1.005827026 1.244129881 0.973357556 1 11.51500159 -9.02219146 0.774371901 0.998534764 1.087602048 0.162570744 0.093454911 1.226040933 1.319218595 0.064285931 0.018712773 9.50E-10 9.02219146 0.089067284 SEK(ac)AAPR ddPTM_HeLa_Curcumin_4h_R1 2 SEKAAPR 7 1 Q92917 Q92917 GPKOW G patch domain and KOW motifs-containing protein 0 1 ; SEK(1)AAPR;SEK(1)AAPR 107.29 0.015397 2701300 1686.81 2378 1892.53 1490.18 1702.34 2493.5 1664.68 1814.07 1977.94 1480.9 FALSE TRUE FALSE 1553.297209 2583.543724 1962.668827 1484.01403 1682.040707 1976.319992 1711.386441 2367.171592 1760.964931 1532.361165 1.013662604 1.685988776 1.280813474 0.968449256 1.097679024 1.289722056 1.116829687 1.54478699 1.149183999 1 10.58154065 -1.000000027 0.048759563 0.417294914 2.577794582 0.030737974 0.223591595 557.8712575 2.07721668 22.40995712 92.14643897 0.099999994 1.000000027 2.160499668 SELGNQS(ph)PSTSSR ddPTM_HeLa_Curcumin_4h_R1 2 SELGNQSPSTSSR 13 0 A0A0A0MSK5;J3KN66;Q5JTV8;Q5JTV8-3;H0YD16 A0A0A0MSK5 TOR1AIP1 Torsin-1A-interacting protein 1 1 0 SELGNQS(0.975)PS(0.023)T(0.001)SSR;SELGNQS(0.996)PS(0.003)TSSR ; 125.33 0.002015 44123000 6619.7 6477.4 7055 8754.6 7296.4 11685.4 7382.8 3127.1 10330.5 6400.2 TRUE FALSE FALSE 6095.74376 7037.277593 7316.464506 8718.375785 7209.395195 9261.716318 7589.941498 4080.538395 9197.269996 6622.606474 0.92044481 1.062614489 1.10477114 1.316456869 1.088603894 1.398500176 1.146065606 0.616152932 1.388768913 1 12.69318342 -6.994667761 3.062768971 0.962729237 1.134182968 0 0.236550414 0.37675931 7.274928742 0.0318221 0.041311964 1.01E-07 6.994667761 0.171453731 SELSQDAEPAGS(ph)QETK ddPTM_HeLa_Curcumin_4h_R1 2 SELSQDAEPAGSQETK 16 0 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2;X6RJY0 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 0 SELSQDAEPAGS(0.996)QET(0.004)K;SELSQDAEPAGS(1)QETK ; 264.01 9.90E-52 59577500 8616.4 6846.6 8130.8 9178.9 9721.9 10878.3 11609.6 8170.6 8548.4 7193.2 TRUE FALSE FALSE 7934.402848 7438.389596 8432.134601 9140.920144 9605.972692 8622.017956 11935.33413 10661.77833 7610.661907 7443.163165 1.065998779 0.999358664 1.132869778 1.228096166 1.290576665 1.158380888 1.603529825 1.432425716 1.022503704 1 12.86170015 -4.856221873 0.455019832 1.014593731 1.717844583 0.771638729 0.090842041 0.91377857 0.180051636 0.020841162 0.313519693 1.39E-05 4.856221873 0.703250852 SEMEVQDAELK ddPTM_HeLa_Curcumin_4h_R1 1 SEMEVQDAELK 11 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 0 167.93 0.0013272 15641000 4098 4015.6 3834.5 4233 4067 4653 3543.4 3041.1 4707.2 3684.1 FALSE FALSE TRUE 3773.638976 4362.690571 3976.609943 4215.484968 4018.503681 3687.91535 3642.818267 3968.31739 4190.831937 3812.122201 0.989905039 1.144425688 1.043148602 1.105810555 1.054138212 0.967417925 0.95558801 1.04097329 1.099343546 1 11.89637865 -3.900088994 19.88873679 1.015183546 3.544615822 0 0.064032747 2466.250858 478481.2041 0.008464328 7178.203316 0.000125867 3.900088994 2.529432276 SEMT(ph)PEELQK ddPTM_HeLa_Curcumin_4h_R1 2 SEMTPEELQK 10 0 P62316;K7ERG4 P62316 SNRPD2 Small nuclear ribonucleoprotein Sm D2 1 0 SEMT(1)PEELQK;SEMT(1)PEELQK ; 114.86 0.015983 15228500 4536.3 4650.2 4308.6 4418.3 5092 4974.1 4725.4 4152.7 3913.9 3733.2 TRUE FALSE FALSE 4177.247068 5052.142567 4468.280506 4400.018245 5031.281226 3942.41559 4857.982006 5418.839113 3484.554962 3862.928422 1.081367971 1.307853011 1.156708077 1.13903696 1.302452615 1.02057692 1.257590479 1.402780099 0.902050098 1 11.91547923 -1.000000002 0.064440196 0.699642534 2.200994128 0.523821926 0.104365678 171.3449368 0.82914831 3.740889185 23.8710221 0.1 1.000000002 1.501351594 ESVNS(ph)PVFGK ddPTM_HeLa_Curcumin_4h_R1 2 ESVNSPVFGK 10 0 Q9UPS8;E7ESJ3;Q9UPS8-2 Q9UPS8 ANKRD26 Ankyrin repeat domain-containing protein 26 1 0 ES(0.313)VNS(0.687)PVFGK;ES(0.021)VNS(0.979)PVFGK ; 136.27 0.0020321 91638000 14669.3 11813.4 13319.4 13068.6 12651.3 13933.6 10051.2 2651.1 14723.7 11368 TRUE FALSE FALSE 13508.20943 12834.49766 13813.02868 13014.5256 12500.44151 11043.6143 10333.20962 3459.408186 13108.54695 11763.03715 1.148360687 1.091087063 1.174273999 1.106391608 1.062688262 0.938840382 0.878447418 0.29409141 1.114384557 1 13.52197298 -4.225886595 1.547153145 1.080362027 8.22E-19 0.941150238 0.059529443 0.241708558 0.496530733 0.010461645 0.405136381 5.94E-05 4.225886595 -1.080362027 down SENPGEIS(ph)LR ddPTM_HeLa_Curcumin_4h_R1 2 SENPGEISLR 10 0 Q96RF0-3;Q96RF0-2;Q96RF0 Q96RF0-3 SNX18 Sorting nexin-18 1 0 SENPGEIS(1)LR;SENPGEIS(1)LR ; 96.23 0.015079 10590200 2729.5 2979.9 3021.4 2833.5 3318.3 4272.9 3447.9 3146.8 2483.9 2844.6 TRUE FALSE FALSE 2513.457195 3237.469278 3133.375742 2821.775728 3278.73144 3386.652374 3544.638794 4106.244834 2211.422384 2943.449638 0.853915475 1.099889475 1.064525005 0.958662819 1.113907776 1.150572556 1.204246456 1.395045045 0.751302946 1 11.52329223 -3.322802652 0.418826732 0.93811639 2.211695367 0.732947663 0.089120304 3.674649498 0.244566283 0.019688885 2.773285599 0.000475551 3.322802652 1.273578977 KSTGS(ph)PTQETQAPFIAK ddPTM_HeLa_Curcumin_4h_R1 1 KSTGSPTQETQAPFIAK 17 1 O15231-3;H0Y704;O15231-2 O15231-3 ZNF185 Zinc finger protein 185 1 0 KS(0.111)T(0.083)GS(0.555)PT(0.25)QET(0.001)QAPFIAK 94.201 0.0015356 28787000 1499.2 1441 1388.2 1667.3 1484.2 1971.2 2165.3 2780 1556.2 1297.6 TRUE FALSE FALSE 1380.536738 1565.553619 1439.647913 1660.401154 1466.501884 1562.3509 2226.05249 3627.609202 1385.488753 1342.691503 1.028186098 1.165981624 1.072210489 1.23662148 1.092210594 1.163596326 1.657903163 2.701744364 1.031874224 1 10.39091215 -4.087238446 1.290874031 1.046240983 3.997460805 0.977642308 0.074194251 0.211582441 0.22518118 0.012277841 0.912085122 8.18E-05 4.087238446 2.951219822 up SEPELTTVAEVDES(ph)NGEEKSEPVSEIETSVVK ddPTM_HeLa_Curcumin_4h_R1 1 SEPELTTVAEVDESNGEEKSEPVSEIETSVVK 32 1 A0JP02;B4DJX4;Q9HAU0-8;Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6 A0JP02 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 0 SEPELT(0.001)T(0.002)VAEVDES(0.684)NGEEKS(0.201)EPVS(0.035)EIET(0.06)S(0.017)VVK 59.636 0.00038788 1471600 997.95 702.52 802.77 1031.3 844.19 1183.6 725.97 552.54 940.23 749.46 TRUE FALSE FALSE 918.9612045 763.2426984 832.5213624 1027.032754 834.1235856 938.1080181 746.3387644 721.0069024 837.0891213 775.5036792 1.18498626 0.984189655 1.073523421 1.324342851 1.075589463 1.20967578 0.962392293 0.929727249 1.079413475 1 9.598989816 -4.625090489 7.669122996 1.103271789 0.938090887 0.325958158 0.096982144 0.216363698 14.0352417 0.014713521 0.055672963 2.37E-05 4.625090489 -0.165180902 SEPHS(ph)PGIPEIFR ddPTM_HeLa_Curcumin_4h_R1 2 SEPHSPGIPEIFR 13 0 Q9UJJ2;Q8ND82 Q9UJJ2 ZNF280C Zinc finger protein 280C 1 0 SEPHS(1)PGIPEIFR;S(0.001)EPHS(0.999)PGIPEIFR ; 87.99 0.0067993 11022100 4970.9 4391.7 4562.2 4447.6 5042.2 7041.5 5692.9 4577.9 5944.8 3920 TRUE FALSE FALSE 4577.44802 4771.298979 4731.279145 4429.19701 4982.075058 5581.013526 5852.627452 5973.680636 5292.670313 4056.219708 1.128501006 1.176292046 1.166425757 1.091951947 1.22825572 1.375914997 1.442877327 1.47272117 1.304828312 1 11.98592008 -1 0.221004361 1.007647794 3.787538217 0.549691408 0.099428525 10.65993036 0.127749524 0.039894413 10.68626573 0.1 1 2.779890423 SEPIPESNDGPVK ddPTM_HeLa_Curcumin_4h_R1 2 SEPIPESNDGPVK 13 0 P30101 P30101 PDIA3 Protein disulfide-isomerase A3 0 0 ; ; 191.33 3.10E-13 10785300 10166.7 8182.4 9974.2 9926.8 10786.4 11529.5 8550.4 5520.4 8124.2 8161 FALSE FALSE TRUE 9361.994967 8889.650196 10343.85263 9885.725532 10657.77922 9138.151736 8790.301212 7203.544547 7232.995586 8444.594143 1.108637645 1.052703072 1.224908202 1.170657271 1.262083061 1.082130364 1.040938269 0.853036206 0.856523767 1 13.04381237 -1.462898287 14.2556393 1.075754175 0.005373944 0 0.131240777 0 0 0.01547064 0 0.034443059 1.462898287 -1.070380231 SEPRPPIS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 3 SEPRPPISSPR 11 1 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 1 0 SEPRPPIS(0.5)S(0.5)PR;SEPRPPIS(0.5)S(0.5)PR;S(0.002)EPRPPIS(0.499)S(0.499)PR ;; 112.02 0.002609 69826000 11985.1 9480 10470.6 11205.7 11480.8 11746.5 6949.9 4112.16 11912 10198.2 TRUE FALSE FALSE 11036.46669 10299.40896 10858.64965 11159.33378 11343.89896 9310.14349 7144.895489 5365.938654 10605.2834 10552.58669 1.04585416 0.976007993 1.029003596 1.057497475 1.074987516 0.882261739 0.677075271 0.508495103 1.004993725 1 13.36530906 -4.718647992 1.867242543 1.02511958 0.507665246 0.966479252 0.032590767 0.050648868 0.30852261 0.004943925 0.033375093 1.91E-05 4.718647992 -0.517454334 SEPRPPISS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SEPRPPISSPR 11 1 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 1 0 SEPRPPIS(0.344)S(0.656)PR 85.287 0.0097949 56134000 7061.3 5169.9 5549.5 6441.1 6349.8 6293.5 4607.4 2283.2 6779.2 5209.6 TRUE FALSE FALSE 6502.390654 5616.763119 5755.169352 6414.448435 6274.082782 4988.157158 4736.671244 2979.337169 6035.538721 5390.633212 1.206238747 1.041948672 1.067623992 1.189924853 1.163886047 0.925337889 0.878685501 0.552687792 1.119634463 1 12.39623903 -4.283679421 1.201113821 1.102633085 0.321261418 0.851032024 0.071622924 0.505999646 0.613707178 0.01356665 0.486510919 5.20E-05 4.283679421 -0.781371667 ALHS(ph)FITPPTTPQLR ddPTM_HeLa_Curcumin_4h_R1 1 ALHSFITPPTTPQLR 15 0 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;J3QR75 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 0 ALHS(0.897)FIT(0.068)PPT(0.017)T(0.017)PQLR 118.52 0.0014346 28565000 815.4 767.69 662.62 839.08 824.9 754.5 588.46 201.6 907.85 816.65 TRUE FALSE FALSE 750.8602296 834.0457028 687.1772801 835.6081093 815.0636063 598.008195 604.9706038 263.0669119 808.2611263 845.0285267 0.88856199 0.987003014 0.813200097 0.988851953 0.964539753 0.707678115 0.715917374 0.31131128 0.956489752 1 9.722856235 -4.220509747 0.997916772 0.944078116 1.88E-15 0.874806353 0.07194961 0.506041648 0.365670913 0.011142299 0.520372364 6.02E-05 4.220509747 -0.944078116 down SEPSPDAPES(ph)PSSCSPSK ddPTM_HeLa_Curcumin_4h_R1 1 SEPSPDAPESPSSCSPSK 18 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 0 SEPSPDAPES(0.31)PS(0.31)S(0.31)CS(0.069)PSK 147.49 0.000155 6127000 1668.5 1371.9 1444.2 1315 1555.8 1696 947.97 701.87 1789.1 1576.8 TRUE FALSE FALSE 1536.436464 1490.480923 1497.723322 1309.558878 1537.248101 1344.230482 974.5674869 915.866932 1592.840206 1631.593683 0.941678361 0.913512315 0.917951165 0.802625612 0.942175811 0.823875758 0.597310162 0.561332727 0.976248084 1 10.67206611 -3.786722384 0.464912553 0.973908346 1.74E-17 0.866481198 0.053459306 1.597181481 0.169615947 0.011971953 0.938814127 0.00016341 3.786722384 -0.973908346 SEPSPDAPESPSSCS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 SEPSPDAPESPSSCSPSK 18 0 Q5SYE7-2;Q5SYE7 Q5SYE7-2 NHSL1 NHS-like protein 1 1 0 SEPSPDAPES(0.001)PS(0.119)S(0.38)CS(0.486)PS(0.014)K 89.502 0.0030365 6466900 1772.3 1497 1492.3 1409.2 1773.2 1991.2 1000.5 786.62 1674.5 1472.9 TRUE FALSE FALSE 1632.020585 1626.394009 1547.605951 1403.369104 1752.055748 1578.202675 1028.571337 1026.456817 1490.811539 1524.083165 1.070821214 1.067129437 1.015434056 0.92079562 1.149580146 1.035509551 0.674878747 0.673491342 0.978169416 1 10.57372591 -4.761292237 12.2484317 1.035605808 0.674039666 0.858141307 0.057775065 0.016949681 133.6197802 0.007724699 0.02567157 1.73E-05 4.761292237 -0.361566143 SEPVKEES(ph)SELEQPFAQDTSSVGPDR ddPTM_HeLa_Curcumin_4h_R1 2 SEPVKEESSELEQPFAQDTSSVGPDR 26 1 Q15424-2;Q15424;Q15424-4;Q15424-3;Q14151 Q15424-2;Q14151 SAFB;SAFB2 Scaffold attachment factor B1;Scaffold attachment factor B2 1 0 SEPVKEES(0.76)S(0.24)ELEQPFAQDTSSVGPDR;SEPVKEES(0.616)S(0.383)ELEQPFAQDTSSVGPDR ; 126.93 1.35E-08 159840000 4139.8 3838.8 4233.3 4334.9 4451.3 5020.2 5071.3 4303.9 4973.5 3767.7 TRUE FALSE FALSE 3812.130462 4170.608767 4390.189822 4316.963332 4398.221155 3978.953931 5213.587029 5616.139297 4427.919493 3898.627295 0.977813516 1.069763394 1.126086053 1.107303419 1.128146094 1.020603825 1.33728788 1.440542753 1.135763734 1 11.92875053 -1 0.406271647 0.994796888 8.863578984 0.689367085 0.077916942 18.66745207 0.218337644 0.015756067 119.4249553 0.1 1 7.868782095 SEPVKEES(ph)SELEQPFAQDTSSVGPDRK ddPTM_HeLa_Curcumin_4h_R1 2 SEPVKEESSELEQPFAQDTSSVGPDRK 27 2 Q15424-2;Q15424;Q15424-4;Q15424-3;Q14151 Q15424-2;Q14151 SAFB;SAFB2 Scaffold attachment factor B1;Scaffold attachment factor B2 1 0 S(0.005)EPVKEES(0.496)S(0.496)ELEQPFAQDT(0.001)SSVGPDRK;SEPVKEES(0.5)S(0.5)ELEQPFAQDTSSVGPDRK ; 93.34 3.69E-06 34209600 2517.04 2904.18 2744.36 3059.94 2458.28 3293.1 2829.42 2942.77 3221.5 2869.93 TRUE FALSE FALSE 2317.813628 3155.204378 2846.068396 3047.278779 2428.966617 2610.073939 2908.80591 3840.007026 2868.10951 2969.659854 0.780498017 1.06248006 0.958381948 1.026137312 0.817927553 0.878913434 0.97950811 1.293079752 0.965804049 1 11.53608198 -4.273882808 3.154493866 0.913481002 1.344242 0.590936307 0.086796511 0.194722827 3.011668848 0.014327492 0.203208433 5.32E-05 4.273882808 0.430760999 SEPVKEESS(ph)ELEQPFAQDTSSVGPDR ddPTM_HeLa_Curcumin_4h_R1 2 SEPVKEESSELEQPFAQDTSSVGPDR 26 1 Q15424-2;Q15424;Q15424-4;Q15424-3;Q14151 Q15424-2;Q14151 SAFB;SAFB2 Scaffold attachment factor B1;Scaffold attachment factor B2 1 0 SEPVKEES(0.184)S(0.816)ELEQPFAQDTSSVGPDR;S(0.001)EPVKEES(0.402)S(0.597)ELEQPFAQDTSSVGPDR ; 103.51 1.19E-07 45697000 2721.8 2164.5 2773.5 2532.5 2748.9 3412.8 3257 2643.9 2799.8 2254 TRUE FALSE FALSE 2506.366658 2351.589735 2876.28835 2522.021186 2716.121163 2704.94681 3348.382654 3450.012939 2492.668945 2332.326332 1.074620915 1.008259309 1.233227233 1.081332895 1.164554516 1.15976344 1.43564072 1.479215362 1.068747932 1 11.18755394 -1 0.341593028 1.022372531 6.631658862 0.820878281 0.067262518 13.35391472 0.168331484 0.018910632 48.4956769 0.1 1 5.609286331 SEPVKEESS(ph)ELEQPFAQDTSSVGPDRK ddPTM_HeLa_Curcumin_4h_R1 2 SEPVKEESSELEQPFAQDTSSVGPDRK 27 2 Q15424-2;Q15424;Q15424-4;Q15424-3;Q14151 Q15424-2;Q14151 SAFB;SAFB2 Scaffold attachment factor B1;Scaffold attachment factor B2 1 0 S(0.001)EPVKEES(0.214)S(0.785)ELEQPFAQDTSSVGPDRK;SEPVKEES(0.22)S(0.78)ELEQPFAQDTSSVGPDRK ; 105.24 8.38E-08 24364000 4027.4 3257.5 3865.9 3962.7 3780.6 4234.2 3289.5 3366.2 4481 4023.6 TRUE FALSE FALSE 3708.62704 3539.063785 4009.173655 3946.303397 3735.518814 3355.979191 3381.794517 4392.538884 3989.445511 4163.419801 0.890764616 0.850037698 0.962952055 0.947851427 0.897223675 0.806063129 0.812263639 1.055031463 0.958213609 1 12.02355332 -9.215764319 0.768277948 1.006167859 0.897472407 0.140155721 0.071546488 0.913631056 0.888196417 0.061832896 0.014017102 6.08E-10 9.215764319 -0.108695452 SEPVKEESSELEQPFAQDTS(ph)SVGPDRK ddPTM_HeLa_Curcumin_4h_R1 1 SEPVKEESSELEQPFAQDTSSVGPDRK 27 2 Q15424-2;Q15424;Q15424-4;Q15424-3;Q14151 Q15424-2;Q14151 SAFB;SAFB2 Scaffold attachment factor B1;Scaffold attachment factor B2 1 0 SEPVKEESSELEQPFAQDT(0.293)S(0.353)S(0.353)VGPDRK 96.777 9.63E-07 91284000 2707.8 2443.4 2389 2775 2389.1 2928 2683.3 2781.7 2832.8 2482.7 TRUE FALSE FALSE 2493.474773 2654.596608 2477.538442 2763.517785 2360.611543 2320.699795 2758.586176 3629.827525 2522.048927 2568.97364 0.970611272 1.033329641 0.964407888 1.075728354 0.918892863 0.903356795 1.073808673 1.412948528 0.981734062 1 11.32697637 -4.293280241 3.24387188 0.984808849 1.458616373 0.878176638 0.048109728 0.068134261 1.159018614 0.006367239 0.077314494 5.09E-05 4.293280241 0.473807524 SEPVS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 SEPVSPSR 8 0 Q14814-4;Q14814;Q14814-6;Q14814-3;Q14814-5;Q14814-2 Q14814-4 MEF2D Myocyte-specific enhancer factor 2D 1 0 S(0.003)EPVS(0.988)PS(0.009)R;S(0.007)EPVS(0.932)PS(0.062)R ; 146.11 0.0023716 121372000 9828.5 7582.3 8393.6 8913.7 10361.5 8363 6457.8 8699.2 7504.6 6584.5 TRUE FALSE FALSE 9050.563854 8237.680226 8704.6742 8876.817471 10237.94588 6628.41953 6638.988488 11351.54603 6681.364156 6813.310885 1.328365021 1.209056854 1.27759827 1.302864 1.502638886 0.972863215 0.974414437 1.666083674 0.980633978 1 12.73414032 -9.349004592 0.93811545 0.99062632 1.269189314 0.248868764 0.199144864 0.782071025 1.164667471 0.155059231 0.035471118 4.48E-10 9.349004592 0.278562993 SEPVS(ph)PSRER ddPTM_HeLa_Curcumin_4h_R1 1 SEPVSPSRER 10 1 Q14814-4;Q14814;Q14814-6;Q14814-3;Q14814-5;Q14814-2 Q14814-4 MEF2D Myocyte-specific enhancer factor 2D 1 0 SEPVS(0.561)PS(0.439)RER 70.089 0.019279 64425000 1182.2 1086.7 828.46 1027.8 653.12 1249 896.24 1159.3 1214.3 928.52 TRUE FALSE FALSE 1088.627623 1180.629506 859.1634564 1023.547236 645.3319706 989.9433209 921.3860823 1512.765233 1081.094328 960.7860009 1.133059413 1.228816307 0.894229782 1.065322803 0.671670872 1.030347361 0.958991993 1.574507988 1.125218651 1 9.90807132 -4.256720394 24.35772547 1.030559896 1.57450831 0.568948146 0.14609027 198.9248331 1026726.281 0.020162871 0.216605458 5.54E-05 4.256720394 0.543948415 SEPVSPS(ph)RER ddPTM_HeLa_Curcumin_4h_R1 1 SEPVSPSRER 10 1 Q14814-4;Q14814;Q14814-6;Q14814-3;Q14814-5;Q14814-2 Q14814-4 MEF2D Myocyte-specific enhancer factor 2D 1 0 SEPVS(0.204)PS(0.796)RER 80.318 0.013729 60047000 1518 1399.3 1532.6 1318.7 1356.4 1661.3 1129.8 2102 1437.4 1395.9 TRUE FALSE FALSE 1397.848698 1520.249257 1589.399504 1313.243569 1340.225816 1316.727653 1161.499147 2742.890124 1279.720816 1444.407421 0.967766212 1.052507232 1.100381707 0.909191929 0.927872425 0.911604049 0.804135406 1.898972605 0.885983274 1 10.49626202 -4.254986609 24.99873499 0.973973788 1.898973019 0.92026207 0.083463669 139.0595016 538717.2206 0.010955524 0.139814244 5.56E-05 4.254986609 0.924999231 SEQSSMSIEFGQES(ph)PEQSLAMDFSR ddPTM_HeLa_Curcumin_4h_R1 4 SEQSSMSIEFGQESPEQSLAMDFSR 25 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 SEQSSMSIEFGQES(0.973)PEQS(0.026)LAMDFS(0.001)R;SEQSS(0.001)MS(0.017)IEFGQES(0.868)PEQS(0.105)LAMDFS(0.01)R;SEQSSMS(0.001)IEFGQES(0.712)PEQS(0.284)LAMDFS(0.003)R;SEQSSMSIEFGQES(0.995)PEQS(0.004)LAMDFSR ;;; 84.809 4.09E-05 89330600 3677.41 3137.63 3176.04 3635.42 3696.27 4319.68 3569.55 3742.7 3621.64 3038.52 TRUE FALSE FALSE 3386.339118 3408.832756 3293.746836 3620.377595 3652.194394 3423.729675 3669.701966 4883.832001 3224.355153 3144.108344 1.077042757 1.084196975 1.0475933 1.151479911 1.161599409 1.088935018 1.167167783 1.553328151 1.025522915 1 11.61843522 -1 0.84406929 1.05245979 167.3171421 0.887249631 0.050134104 158.8898509 0.428769922 0.009071093 50730.91018 0.1 1 166.2646823 SEREEVSSWR ddPTM_HeLa_Curcumin_4h_R1 1 SEREEVSSWR 10 1 Q14152;Q14152-2 Q14152 EIF3A Eukaryotic translation initiation factor 3 subunit A 0 0 128.35 0.0027194 11867000 1800.1 1385 1760.4 1665.8 1644 2015.1 1510.8 1547.2 1910.9 1649 FALSE FALSE TRUE 1657.620186 1504.713229 1825.641973 1658.907361 1624.396374 1597.145545 1553.188982 2018.934158 1701.279051 1706.302627 0.971469046 0.881856011 1.069940316 0.972223411 0.951997815 0.936027127 0.910265833 1.183221619 0.99705587 1 10.73665783 -4.250367645 24.91018742 0.974423651 1.183221746 0.626693128 0.049965568 796.707941 1792471.021 0.00666612 0.134779891 5.62E-05 4.250367645 0.208798095 SES(ph)DLEDVGPTAEWNGDGSGSLRR ddPTM_HeLa_Curcumin_4h_R1 2 SESDLEDVGPTAEWNGDGSGSLRR 24 1 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 0 S(0.227)ES(0.758)DLEDVGPT(0.013)AEWNGDGSGS(0.002)LRR;S(0.05)ES(0.95)DLEDVGPTAEWNGDGSGSLRR ; 113.67 5.63E-07 19453900 2529 2446.3 2445.1 2943.8 2536.3 2104 1626.05 1209.16 2925.1 2764.4 TRUE FALSE FALSE 2328.826981 2657.747271 2535.717557 2931.619336 2506.056279 1667.606683 1671.672587 1577.827318 2604.223848 2860.462694 0.814143455 0.929131947 0.886471116 1.02487592 0.876101717 0.582984944 0.584406358 0.551598635 0.91042049 1 11.48203281 -5.282028773 4.363204855 0.917532736 0.570186588 0.891558 0.05565365 0.06293702 2.988626532 0.010880835 0.026580959 5.22E-06 5.282028773 -0.347346148 SES(ph)ELIDELSEDFDR ddPTM_HeLa_Curcumin_4h_R1 2 SESELIDELSEDFDR 15 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E7EVY3;E9PCH5;P20810-3;E7EQ12;E7EQA0;H0Y7F0;A0A0A0MR45;H0Y9H6;H0YD33;D6RC54 P20810-6 CAST Calpastatin 1 0 S(0.022)ES(0.978)ELIDELSEDFDR;SES(0.973)ELIDELS(0.027)EDFDR ; 354.25 1.24E-166 184561000 625.43 584.9 348.1 431.11 724.56 474.14 431.73 399.12 262.88 378.74 TRUE FALSE FALSE 575.9265555 635.4561497 361.0008922 429.326181 715.9200952 375.7980193 443.8431819 520.8098507 234.0427217 391.9011868 1.469570838 1.621470338 0.921152843 1.095495996 1.82678726 0.958910133 1.132538499 1.328931548 0.597198298 1 8.614346132 -9.539743047 1.339258038 1.002018891 1.309734066 0.244111511 0.302962529 0.671965691 2.18106253 0.183621117 0.044932377 2.89E-10 9.539743047 0.307715175 SES(ph)ELIDELSEDFDRSECK ddPTM_HeLa_Curcumin_4h_R1 1 SESELIDELSEDFDRSECK 19 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E7EVY3;E9PCH5;P20810-3;E7EQ12;E7EQA0;H0Y7F0;A0A0A0MR45;H0Y9H6;H0YD33;D6RC54 P20810-6 CAST Calpastatin 1 0 S(0.037)ES(0.963)ELIDELSEDFDRSECK 157.02 1.24E-05 19335000 1979.1 1833 1880.1 1785.5 1789.1 3195.9 2027.4 1625.5 2362.7 2021 TRUE FALSE FALSE 1822.452147 1991.436352 1949.77816 1778.112074 1767.766151 2533.034315 2084.283388 2121.107467 2103.517721 2091.2296 0.871473963 0.95228011 0.93235968 0.850271091 0.8453238 1.211265523 0.996678408 1.014287225 1.005876027 1 11.03013575 -5.278590517 24.99830187 0.926195122 1.06633721 0.459686544 0.075086255 589.1592384 858716.6804 0.011199973 0.025098115 5.27E-06 5.278590517 0.140142088 EIEMSVDDDDINSS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 EIEMSVDDDDINSSK 15 0 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 0 EIEMSVDDDDINS(0.004)S(0.996)K 104.41 0.0028199 56706000 4027.5 3027.2 2986 3719.4 3415.1 5899.9 7413.6 14561 3645.5 3137.5 TRUE FALSE FALSE 3708.719125 3288.857679 3096.663787 3704.010108 3374.377163 4676.194234 7621.605663 19000.58187 3245.597771 3246.527891 1.142364781 1.01303848 0.953838652 1.140914304 1.039380309 1.440367799 2.347617491 5.85258544 0.999713503 1 11.66468189 -4.08633194 1.523260794 1.059926428 9.430370984 0.996053424 0.090601367 0.074387478 0.113685848 0.013974565 1.053606657 8.20E-05 4.08633194 8.370444556 up SES(ph)ETSTMAAK ddPTM_HeLa_Curcumin_4h_R1 1 SESETSTMAAK 11 0 A0A087WVF1;Q96B23-2;Q96B23 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 0 S(0.013)ES(0.434)ET(0.434)S(0.097)T(0.022)MAAK 164.81 0.00027259 24677000 3020.4 2453.6 2366.6 2691.3 2684.4 3177.8 1580.7 1260.4 3389 2188.5 TRUE FALSE FALSE 2781.332153 2665.678251 2454.308278 2680.164114 2652.390283 2518.688459 1625.050188 1644.690158 3017.235179 2264.550212 1.228205115 1.177133647 1.083795036 1.183530442 1.17126583 1.112224602 0.717603955 0.726276745 1.332377248 1 11.14500881 -4.765541794 8.168890835 1.123528377 0.720647871 0.787358715 0.089605256 0.036950332 20.66951941 0.012527251 0.041353915 1.72E-05 4.765541794 -0.402880506 SES(ph)FSSEDLIPSR ddPTM_HeLa_Curcumin_4h_R1 1 SESFSSEDLIPSR 13 0 A0A0A0MR69;Q9P219-3;Q9P219-2;Q9P219 A0A0A0MR69 CCDC88C Protein Daple 1 0 S(0.103)ES(0.864)FS(0.031)S(0.002)EDLIPSR 163.33 0.00019023 6810400 945.45 1188.8 1285.1 1301.7 1307.4 1575.4 942.5 299.08 1130.1 1021.3 TRUE FALSE FALSE 870.6166349 1291.554575 1332.726936 1296.31391 1291.810109 1248.644282 968.9440134 390.2681152 1006.130857 1056.790099 0.823831181 1.222148633 1.261108462 1.22665221 1.222390435 1.181544266 0.916874613 0.369295772 0.9520631 1 10.04547314 -2.714709873 8.309530215 0.985311651 0.616618221 0 0.263945229 0 0 0.036133888 0 0.001928813 2.714709873 -0.368693429 VADPDHDHTGFLT(ph)EY(ph)VATR ddPTM_HeLa_Curcumin_4h_R1 2 VADPDHDHTGFLTEYVATR 19 0 P28482-2;P28482 P28482-2 MAPK1 Mitogen-activated protein kinase 1 2 0 VADPDHDHT(0.245)GFLT(0.859)EY(0.886)VAT(0.009)R;VADPDHDHT(0.002)GFLT(0.994)EY(0.994)VAT(0.01)R ; 128.8 6.46E-05 13094800 1707.42 1548.05 1951.15 1967.19 1669.37 4513.4 7343.9 16508.2 1254.9 1931.02 TRUE FALSE FALSE 1572.275905 1681.856544 2023.461335 1959.050289 1649.463853 3577.269963 7549.950069 21541.47419 1117.24061 1998.122801 0.786876514 0.841718308 1.01268117 0.98044539 0.825506747 1.790315371 3.778521552 10.780856 0.559145118 1 10.96442954 -4.078187939 1.443807368 0.900544197 18.47019829 0.995900077 0.191063077 0.067610562 0.090414725 0.024663904 1.928669191 8.35E-05 4.078187939 17.56965409 up LPNLSS(ph)PSAEGPPGPPSGPAPR ddPTM_HeLa_Curcumin_4h_R1 1 LPNLSSPSAEGPPGPPSGPAPR 22 0 O60784-3;O60784-4;O60784;O60784-2 O60784-3 TOM1 Target of Myb protein 1 1 0 LPNLS(0.016)S(0.984)PSAEGPPGPPSGPAPR 218.88 6.58E-23 5787000 783.33 710.26 869.15 576.68 846.58 938.08 1222.8 2248 677.33 462.92 TRUE FALSE FALSE 721.3286039 771.6517095 901.3614636 574.293851 836.4850864 743.5116337 1257.108477 2933.404851 603.0285936 479.0064355 1.505884995 1.610942259 1.881731427 1.198927213 1.746291958 1.5521955 2.624408325 6.123936202 1.258915432 1 8.903901229 -4.07431867 1.527277218 1.345844555 9.855923824 0.965456227 0.264396136 0.254565106 0.38209844 0.046226211 3.707738846 8.43E-05 4.07431867 8.510079269 up LQSVQATGPSS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 2 LQSVQATGPSSPGR 14 0 D6REY2;P23508;P23508-2;A0A096LNU0 D6REY2 MCC Colorectal mutant cancer protein 1 0 LQSVQATGPS(0.028)S(0.972)PGR;LQSVQATGPS(0.009)S(0.991)PGR ; 199.33 9.09E-07 95467000 6560.9 5676.5 5758.5 6065.3 6466.4 7253 5583.8 1745.86 6091 6039.1 TRUE FALSE FALSE 6041.597842 6167.151366 5971.915076 6040.203396 6389.292403 5748.646042 5740.4664 2278.164677 5422.832539 6248.958275 0.9668168 0.986908712 0.955665699 0.966593651 1.022457204 0.919936698 0.918627737 0.364567113 0.867797847 1 12.60939999 -4.219925418 2.854041198 0.979795165 0.217295691 0.940662334 0.04444644 0.049591317 0.507951575 0.003819542 0.091252101 6.03E-05 4.219925418 -0.762499474 down YS(ph)GSYNDYLR ddPTM_HeLa_Curcumin_4h_R1 2 YSGSYNDYLR 10 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 1 0 Y(0.013)S(0.981)GS(0.006)YNDYLR;Y(0.001)S(0.97)GS(0.029)YNDYLR ; 113.07 0.0062856 29328400 2230.69 1860.42 2070.67 1985.62 2102.4 3106.4 2919.8 3502.2 2116.82 2053.55 TRUE FALSE FALSE 2054.128533 2021.226415 2147.410852 1977.404031 2077.330253 2462.097624 3001.72173 4570.004658 1884.610142 2124.91071 0.966689341 0.95120534 1.010588747 0.930582175 0.977608256 1.158682863 1.412634289 2.150680797 0.886912628 1 11.0531865 -4.071997126 1.202565649 0.977645177 3.112249661 0.986670235 0.042140989 0.127829282 0.113891477 0.00481706 0.377404922 8.47E-05 4.071997126 2.134604484 up SES(ph)NEDLFGLVPFDEITGSQQQK ddPTM_HeLa_Curcumin_4h_R1 1 SESNEDLFGLVPFDEITGSQQQK 23 0 H0Y9P1;Q9NSY1 H0Y9P1 BMP2K BMP-2-inducible protein kinase 1 0 S(0.187)ES(0.813)NEDLFGLVPFDEITGSQQQK 114.71 2.42E-06 3658300 1194.5 1134.2 1221.4 1199.3 1581.9 1957 1583.8 782.81 1506.6 913.01 TRUE FALSE FALSE 1099.954065 1232.235194 1266.666158 1194.337614 1563.036876 1551.09614 1628.237165 1021.485165 1341.329749 944.7370295 1.16429655 1.304315546 1.34076057 1.264201124 1.654467674 1.641828458 1.723481894 1.081237565 1.419791654 1 9.883768996 -6.952921155 0.643076564 1.036867163 1.535565185 0.166737227 0.216032157 0.371067589 0.322471568 0.046400904 0.069327011 1.11E-07 6.952921155 0.498698022 SES(ph)PEPAATCSLPSDLTR ddPTM_HeLa_Curcumin_4h_R1 1 SESPEPAATCSLPSDLTR 18 0 Q9NS37;E9PIM0 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 1 0 S(0.041)ES(0.959)PEPAATCSLPSDLTR 101.72 0.0012869 5836700 462.93 342.12 264.08 383.48 457.08 771.42 352.16 210.45 552.77 357.27 TRUE FALSE FALSE 426.288602 371.6913283 273.8670371 381.8932614 451.6296195 611.4187963 362.0406618 274.6152362 492.132514 369.6851059 1.153112731 1.005426841 0.74081166 1.03302312 1.221660306 1.653890802 0.979321742 0.742835543 1.331220831 1 8.53015311 -5.773455821 23.87362116 1.038334408 1.173309828 0.036150753 0.254222796 299.5993431 595229.3338 0.036271991 0.06615753 1.68E-06 5.773455821 0.13497542 SES(ph)PFRETEPLVS(ph)PHQDK ddPTM_HeLa_Curcumin_4h_R1 1 SESPFRETEPLVSPHQDK 18 1 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 2 0 S(0.447)ES(0.551)PFRET(0.002)EPLVS(1)PHQDK 98.533 0.0012207 7872000 2616 2178.8 2369 2837 2640.9 2863 2921.6 2559.9 3067.4 2219.2 TRUE FALSE FALSE 2408.94084 2367.125763 2456.797224 2825.261246 2609.408992 2269.181527 3003.572233 3340.401726 2730.913894 2296.317035 1.049045408 1.030835781 1.069885903 1.230344592 1.136345266 0.988183031 1.30799545 1.454677936 1.189258213 1 11.16510612 -1 0.482496159 1.028573909 13.130964 0.578028719 0.093071187 33.50809726 0.336095368 0.016125954 410.1212176 0.1 1 12.10239009 AS(ph)LASLDS(ph)NPSTNEK ddPTM_HeLa_Curcumin_4h_R1 1 ASLASLDSNPSTNEK 15 0 Q96BY6;H7C0I3;A0A2R8YD85;Q96BY6-3 Q96BY6 DOCK10 Dedicator of cytokinesis protein 10 2 0 AS(0.585)LAS(0.415)LDS(0.967)NPS(0.027)T(0.006)NEK 147.75 0.0011113 6611700 3608.9 3269.6 3583.7 3263.9 3343.3 4171.7 3223.7 891.35 4457.9 3710.6 TRUE FALSE FALSE 3323.251757 3552.209655 3716.515075 3250.394847 3303.433331 3306.442395 3314.148346 1163.118512 3968.879523 3839.543074 0.865533136 0.925164684 0.967957646 0.846557724 0.860371473 0.861155177 0.863162174 0.302931492 1.033685375 1 11.90671892 -4.217832783 2.875816032 0.920496486 0.154508009 0.899977855 0.061299204 0.11765565 1.224605544 0.009071762 0.219035245 6.06E-05 4.217832783 -0.765988477 down SES(ph)PIPVAEQGTLMR ddPTM_HeLa_Curcumin_4h_R1 2 SESPIPVAEQGTLMR 15 0 P86452 P86452 ZBED6 Zinc finger BED domain-containing protein 6 1 0 S(0.005)ES(0.995)PIPVAEQGTLMR;S(0.222)ES(0.778)PIPVAEQGTLMR ; 162.64 0.00027731 50661000 3824 2674 2682.1 3147.4 3178.5 3664.4 2723.1 1721.81 3611.2 2694.2 TRUE FALSE FALSE 3521.326365 2905.128645 2781.500985 3134.376893 3140.598463 2904.362134 2799.502857 2246.781943 3215.060395 2787.823249 1.26310962 1.042077774 0.997732186 1.124309762 1.126541456 1.041802824 1.004189508 0.805926969 1.153251159 1 11.44492338 -3.52901846 0.89486603 1.112291089 7.60E-13 0.577656949 0.075268747 4.890897567 1.145053398 0.016358898 7.295518782 0.000295789 3.52901846 -1.112291089 SES(ph)PKEPEQLR ddPTM_HeLa_Curcumin_4h_R1 3 SESPKEPEQLR 11 1 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 1 0 S(0.002)ES(0.998)PKEPEQLR;S(0.266)ES(0.734)PKEPEQLR;S(0.001)ES(0.999)PKEPEQLR ;; 181.76 0.0012707 1428417000 12955.7 12229.6 11975 12390.3 14336.9 14947.3 13474.8 16677.9 12656.7 11702 TRUE FALSE FALSE 11930.24267 13286.67213 12418.80403 12339.03222 14165.94183 11847.06149 13852.86662 21762.91493 11268.29168 12108.64363 0.985266644 1.09728823 1.025614793 1.019026788 1.169903274 0.978397073 1.14404776 1.797304108 0.930599002 1 13.56374965 -4.257147795 2.92336349 1.016526014 1.93591162 0.928564977 0.063789942 0.06771034 0.812638986 0.008366647 0.146664784 5.53E-05 4.257147795 0.919385606 SES(ph)PPAELPSLR ddPTM_HeLa_Curcumin_4h_R1 1 SESPPAELPSLR 12 0 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 0 S(0.229)ES(0.767)PPAELPS(0.004)LR 94.688 0.012271 140120000 4716.6 3895.4 4236.3 5829.1 5297.5 4203.6 3675.4 2826.2 4860.7 4032.8 TRUE FALSE FALSE 4343.276133 4232.101018 4393.301005 5804.980729 5234.330772 3331.725976 3778.521832 3687.89537 4327.493371 4172.9395 1.040819339 1.014177421 1.052807261 1.3911011 1.254350985 0.798412241 0.905482055 0.883764399 1.03703717 1 12.02684829 -5.236350982 24.99062872 1.064041246 0.866845803 0.42149548 0.125550984 770.4357592 767432.1246 0.019839307 0.050558145 5.80E-06 5.236350982 -0.197195443 SES(ph)PPAELPSLRR ddPTM_HeLa_Curcumin_4h_R1 2 SESPPAELPSLRR 13 1 Q14669;Q14669-2;Q14669-3;G5E9G6;H7C1L9 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 0 S(0.192)ES(0.808)PPAELPSLRR;S(0.169)ES(0.831)PPAELPSLRR ; 109.55 0.0019425 75846000 5024.9 4248.2 4413.5 4540.6 4193.4 5142.4 4092.3 2582.1 5968 4898.6 TRUE FALSE FALSE 4627.173863 4615.395478 4577.068193 4521.8122 4143.396444 4075.808273 4207.118924 3369.370403 5313.325331 5068.825985 0.912868952 0.910545261 0.902983887 0.892082745 0.817427242 0.804093154 0.829998689 0.664724024 1.048235893 1 12.30743592 -1.76799977 0.186138345 1.006420432 3.60E-14 0.8698295 0.036772953 9.324908809 0.132745494 0.036914813 2.543399266 0.017060833 1.76799977 -1.006420432 SES(ph)PPPLSDPK ddPTM_HeLa_Curcumin_4h_R1 4 SESPPPLSDPK 11 0 Q15059;Q15059-2 Q15059 BRD3 Bromodomain-containing protein 3 1 0 S(0.001)ES(0.999)PPPLSDPK;SES(1)PPPLSDPK;S(0.073)ES(0.927)PPPLSDPK;SES(1)PPPLSDPK ;;; 179.6 0.00016046 1400060000 37933.9 30240.7 30173.2 32584.2 32155 38041.2 31998.3 29754.5 37678.4 31387.5 TRUE FALSE FALSE 34931.39179 32854.57136 31291.44534 32449.37521 31771.57263 30151.02631 32896.08618 38826.51008 33545.17379 32478.21329 1.07553305 1.011588016 0.963459568 0.999112079 0.978242625 0.928346213 1.012866252 1.19546324 1.032851576 1 14.98718465 -9.991093687 2.412637592 0.999575897 1.02752549 0 0.070122588 1.399872582 14.81063816 0.058634315 0.010610623 1.02E-10 9.991093687 0.027949593 SES(ph)PQAEALLLPR ddPTM_HeLa_Curcumin_4h_R1 1 SESPQAEALLLPR 13 0 A0A087WXB3;A0A087X223;A0A087WYW1;Q96NU1-4;Q96NU1-5 A0A087WXB3 SAMD11 Sterile alpha motif domain-containing protein 11 1 0 S(0.26)ES(0.74)PQAEALLLPR 114.01 0.0031894 2233100 1160.8 869.63 914.68 1161.9 892.74 1141.1 1134.4 383.44 1049.8 778.78 TRUE FALSE FALSE 1068.921455 944.7969422 948.5788454 1157.092366 882.0946586 904.4229972 1166.228211 500.3490909 934.6395665 805.842547 1.326464406 1.172433679 1.177126784 1.435878969 1.094624082 1.122332148 1.447215979 0.620901804 1.159829014 1 9.654354169 -4.243924283 24.62044958 1.187126495 0.620901229 0.6110635 0.140631355 1852.093995 2603384.889 0.022119503 0.884525356 5.70E-05 4.243924283 -0.566225266 SES(ph)PQEALLLPR ddPTM_HeLa_Curcumin_4h_R1 1 SESPQEALLLPR 12 0 H7BY14;A0A087WYU3;Q96NU1-6;Q96NU1;I7G285 H7BY14 SAMD11 Sterile alpha motif domain-containing protein 11 1 0 S(0.003)ES(0.997)PQEALLLPR 125.47 0.0030063 4198300 1536.3 1451.5 1379.5 1538.1 1722.4 1729 1332 745.85 1553.4 1341.2 TRUE FALSE FALSE 1414.700234 1576.961192 1430.625484 1531.73575 1701.861505 1370.38591 1369.372335 973.2562315 1382.995906 1387.8066 1.019378517 1.136297516 1.030853639 1.103709803 1.226295872 0.987447322 0.986716978 0.701290966 0.996533599 1 10.43859082 -4.189470236 2.202155824 1.040945009 0.570472028 0.676693361 0.073674711 0.419600756 1.949541174 0.01114111 0.411143137 6.46E-05 4.189470236 -0.470472981 SES(ph)PSLTQER ddPTM_HeLa_Curcumin_4h_R1 1 SESPSLTQER 10 0 Q9BXW9;Q9BXW9-1;H7BZJ7;Q9BXW9-3 Q9BXW9 FANCD2 Fanconi anemia group D2 protein 1 0 S(0.209)ES(0.707)PS(0.042)LT(0.042)QER 95.094 0.015833 38155000 1925.8 1878.4 2030.3 2079.3 2100.8 2507 2520.8 2792.7 2208.4 2052.1 TRUE FALSE FALSE 1773.370898 2040.760526 2105.544704 2070.696408 2075.749332 1987.01994 2591.526864 3644.181374 1966.144045 2123.410322 0.835152245 0.96107686 0.991586356 0.975174881 0.977554508 0.93576824 1.220455056 1.716192738 0.925936935 1 11.05216747 -4.294940934 1.813339433 0.934735708 1.94218028 0.958802229 0.048543207 0.146375559 0.506934944 0.009751016 0.244927483 5.07E-05 4.294940934 1.007444572 TPTSS(ph)PASSPLVAK ddPTM_HeLa_Curcumin_4h_R1 2 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 0 T(0.006)PT(0.001)S(0.01)S(0.981)PAS(0.002)SPLVAK;T(0.221)PT(0.001)S(0.072)S(0.707)PASSPLVAK ; 202.13 6.01E-09 143144000 5499.4 4564 5028.6 4830.4 4592.8 6139.2 3973.4 1708.36 5344.6 4455 TRUE FALSE FALSE 5064.116687 4958.491823 5214.96434 4810.413085 4538.03386 4865.860717 4084.88291 2229.2311 4758.310752 4609.810918 1.098551931 1.075638873 1.131275107 1.043516355 0.9844295 1.055544534 0.886128083 0.483584064 1.032213866 1 12.17049186 -4.21705944 1.824227276 1.052813252 0.252745194 0.944797903 0.041647067 0.182328132 0.555235274 0.007155199 0.258198291 6.07E-05 4.21705944 -0.800068058 down SES(ph)PVPQNEK ddPTM_HeLa_Curcumin_4h_R1 3 SESPVPQNEK 10 0 Q9UIF8-4;Q9UIF8-2;Q9UIF8-5;Q9UIF8-3;Q9UIF8 Q9UIF8-4 BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 1 0 S(0.005)ES(0.995)PVPQNEK;S(0.032)ES(0.968)PVPQNEK;S(0.011)ES(0.989)PVPQNEK ;; 174.23 0.00041782 58618500 19874.5 13422.6 16267.1 17141.3 15338.6 18662.2 14125 7133.65 17711.6 14438.6 TRUE FALSE FALSE 18301.41235 14582.78973 16869.97304 17070.37384 15155.69721 14791.44935 14521.30948 9308.667046 15768.68179 14940.34028 1.224966233 0.976068113 1.129155878 1.142569281 1.01441446 0.990034302 0.971953062 0.623055893 1.055443283 1 13.86692539 -3.839394647 0.981192929 1.098590887 5.17E-14 0.759056576 0.074896694 1.705409083 0.719231765 0.014373824 2.408942732 0.000144746 3.839394647 -1.098590887 S(ph)SDIVSSVR ddPTM_HeLa_Curcumin_4h_R1 4 SSDIVSSVR 9 0 Q14C86-4;Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;F8W9S7;Q14C86-3;H0Y4E7;H0Y7I9;C9IZ08 Q14C86-4 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 0 S(0.975)S(0.025)DIVSSVR;S(0.877)S(0.122)DIVS(0.001)SVR;S(0.968)S(0.032)DIVSSVR;S(0.95)S(0.05)DIVSSVR ;;; 178.46 0.0013151 183490200 7572.5 5808.1 5848.19 6540.78 5576.38 9850.4 9101.38 14332.3 6295.9 5946.77 TRUE FALSE FALSE 6973.128635 6310.126284 6064.929066 6513.715985 5509.885311 7807.316003 9356.740228 18702.15229 5605.255522 6153.419815 1.133211912 1.025466565 0.985619257 1.058552184 0.895418398 1.268776751 1.520575633 3.039310311 0.910917131 1 12.58717271 -4.070898228 1.563083293 1.047516369 4.596379633 0.977480062 0.091744377 0.16332774 0.256123899 0.012395629 1.015294937 8.49E-05 4.070898228 3.548863264 up SESADQTVS(ph)PPTPFAR ddPTM_HeLa_Curcumin_4h_R1 1 SESADQTVSPPTPFAR 16 0 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 1 0 SESADQT(0.083)VS(0.783)PPT(0.135)PFAR 102.72 0.0033383 0 2662.2 2060.8 2340.5 2321.2 1926.7 1506 1002.9 879.51 2646.7 2059.1 TRUE FALSE FALSE 2451.484061 2238.926369 2427.240989 2311.595489 1903.725361 1193.638624 1031.038675 1147.66855 2356.363632 2130.653572 1.150578439 1.050816707 1.139200207 1.084923199 0.893493614 0.560221821 0.483907233 0.538646247 1.105934659 1 11.05708033 -5.375045057 2.354794329 1.077630766 0.506794917 0.969956581 0.044141531 0.047733102 0.511952843 0.009027793 0.024135652 4.22E-06 5.375045057 -0.570835849 SESAPT(ph)LHPYSPLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SESAPTLHPYSPLSPK 16 0 Q8WUF5;K7EN03 Q8WUF5 PPP1R13L RelA-associated inhibitor 2 0 S(0.042)ES(0.259)APT(0.693)LHPY(0.007)S(0.26)PLS(0.74)PK 95.307 0.0041969 5627600 1922.1 1431.4 1793.2 1775.7 1835.3 2860.6 2145.5 1296.8 2005.5 1394.2 TRUE FALSE FALSE 1769.963757 1555.123838 1859.657569 1768.352624 1813.415246 2267.279314 2205.696956 1692.18835 1785.501668 1442.648346 1.226885097 1.077964593 1.289058123 1.225768309 1.25700435 1.571609131 1.528922112 1.172973549 1.237655505 1 10.49450396 -7.058675667 0.184744138 0.897097402 1.556159827 0.268733949 0.143433445 2.052753037 0.315919915 0.42696788 0.539217369 8.74E-08 7.058675667 0.659062424 SESAPTLHPYSPLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 SESAPTLHPYSPLSPK 16 0 Q8WUF5;K7EN03 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 0 SESAPTLHPYS(0.002)PLS(0.998)PK;SESAPTLHPYS(0.039)PLS(0.961)PK;SESAPTLHPYS(0.297)PLS(0.703)PK;SESAPTLHPYS(0.02)PLS(0.98)PK ;;; 170.11 0.00012724 508614000 15175.2 12068.3 12987.7 12500.2 15724.3 20332.9 14313.1 8261.5 18180.9 13624.1 TRUE FALSE FALSE 13974.06691 13111.43008 13469.03559 12448.47748 15536.79799 16115.62734 14714.68706 10780.39332 16186.50076 14097.53646 0.991241764 0.930051156 0.955417681 0.883025025 1.102093124 1.143152024 1.043777195 0.76470051 1.148179386 1 13.78315545 -4.254930999 24.7900118 1.000477323 0.76470039 0.424075513 0.086742957 466.7912506 1777924.964 0.010470312 0.133098415 5.56E-05 4.254930999 -0.235776933 SESDLEDVGPTAEWNGDGS(ph)GSLRR ddPTM_HeLa_Curcumin_4h_R1 2 SESDLEDVGPTAEWNGDGSGSLRR 24 1 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 0 SESDLEDVGPT(0.002)AEWNGDGS(0.499)GS(0.499)LRR;SESDLEDVGPTAEWNGDGS(0.5)GS(0.5)LRR ; 84.398 7.97E-05 14385400 5198.5 4597.27 5465.05 5974.58 6005.88 4112.5 3754.89 2878.02 6381.58 5390.73 TRUE FALSE FALSE 4787.03324 4994.637534 5667.589561 5949.858771 5934.263804 3259.521143 3860.242108 3755.515049 5681.53664 5578.057466 0.858190018 0.895408046 1.016050766 1.066654262 1.063858492 0.584346999 0.692040577 0.673265751 1.018551113 1 12.44554708 -5.256618846 24.99873438 0.952912464 0.654100044 0.809023765 0.073966044 165.456538 858034.6648 0.012386368 0.030495217 5.54E-06 5.256618846 -0.29881242 SESDLEDVGPTAEWNGDGSGS(ph)LRR ddPTM_HeLa_Curcumin_4h_R1 1 SESDLEDVGPTAEWNGDGSGSLRR 24 1 Q9H0B6;Q9H0B6-2;A8MZ87 Q9H0B6 KLC2 Kinesin light chain 2 1 0 SESDLEDVGPTAEWNGDGS(0.453)GS(0.547)LRR 104.39 2.10E-06 9001800 1851.8 1324.9 1497.5 1709.7 1384.2 2338.8 1724.5 1396 1715 1740.9 TRUE FALSE FALSE 1705.228076 1439.418452 1552.998667 1702.625714 1367.694319 1853.706516 1772.884829 1821.633974 1526.868791 1801.396145 0.946614702 0.79905714 0.862108355 0.945170066 0.759241282 1.029038794 0.984172656 1.011234524 0.847603008 1 10.81489976 -3.18787508 13.56470299 0.946686272 0.927549086 0 0.094392374 0 0 0.01225379 0 0.000648821 3.18787508 -0.019137185 SESDLSQPES(ph)DEEGYALSGR ddPTM_HeLa_Curcumin_4h_R1 1 SESDLSQPESDEEGYALSGR 20 0 Q15751;H0YNB1 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 0 SESDLSQPES(1)DEEGYALSGR 186.15 1.30E-29 0 1119.5 745.35 762.9 852.39 1041 892.91 617.1 397.88 948.8 1108.1 TRUE FALSE FALSE 1030.890394 809.7747328 791.1737451 848.863036 1028.586755 707.7104008 634.4141652 519.1917804 844.7190138 1146.606393 0.89907958 0.706236018 0.690013374 0.740326446 0.897070487 0.617221747 0.553297251 0.452807331 0.736712284 1 10.16315451 -4.103647073 0.19535471 1.051069437 1.00E-17 0.445530885 0.118320509 5.761005747 0.193130674 0.125432137 1.519938746 7.88E-05 4.103647073 -1.051069437 SESELIDELS(ph)EDFDRSECK ddPTM_HeLa_Curcumin_4h_R1 5 SESELIDELSEDFDRSECK 19 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E7EVY3;E9PCH5;P20810-3;E7EQ12;E7EQA0;H0Y7F0;A0A0A0MR45;H0Y9H6;H0YD33;D6RC54 P20810-6 CAST Calpastatin 1 0 SESELIDELS(1)EDFDRSECK;SESELIDELS(1)EDFDRSECK;SESELIDELS(1)EDFDRSECK;SESELIDELS(1)EDFDRSECK;S(0.001)ES(0.001)ELIDELS(0.998)EDFDRS(0.001)ECK ;;;; 117.38 0.00011925 75197600 10788.54 8434.93 8944.26 10109.64 10395.77 12480.66 10054.03 11659.81 10290.58 9768.23 TRUE FALSE FALSE 9934.615675 9164.007764 9275.742144 10067.80899 10271.80723 9892.03043 10336.11902 15214.83239 9161.72912 10107.67527 0.982878398 0.906638522 0.917692931 0.996055841 1.01623835 0.978665239 1.022601019 1.505275149 0.906413085 1 13.3031636 -4.25915704 4.090916981 0.982047298 1.550958085 0.937384431 0.04154792 0.035958402 1.287998738 0.005181529 0.060253636 5.51E-05 4.25915704 0.568910787 SESELIDELSEDFDR ddPTM_HeLa_Curcumin_4h_R1 4 SESELIDELSEDFDR 15 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E7EVY3;E9PCH5;P20810-3;E7EQ12;E7EQA0;H0Y7F0;A0A0A0MR45;H0Y9H6;H0YD33;D6RC54 P20810-6 CAST Calpastatin 0 0 ;;; ;;; 313.52 3.38E-107 51314000 4683.76 3884.81 4484.94 4012.1 5105.26 5376.43 3828.07 3731.47 4522.85 4156.62 FALSE FALSE TRUE 4313.035454 4220.595666 4651.155822 3995.498993 5044.383109 4261.297813 3935.475341 4869.178025 4026.704671 4301.062236 1.002783782 0.981291466 1.081397005 0.928956331 1.172822627 0.990754744 0.91500079 1.132087321 0.936211673 1 12.07047729 SESELIDELSEDFDRS(ph)ECK ddPTM_HeLa_Curcumin_4h_R1 1 SESELIDELSEDFDRSECK 19 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E7EVY3;E9PCH5;P20810-3;E7EQ12;E7EQA0;H0Y7F0;A0A0A0MR45;H0Y9H6;H0YD33;D6RC54 P20810-6 CAST Calpastatin 1 0 SESELIDELS(0.078)EDFDRS(0.921)ECK 49.993 0.019228 2407600 686.05 466.3 589.09 607.58 564.94 743.12 521.35 408.62 574.88 396.66 TRUE FALSE FALSE 631.7484186 506.6048942 610.9221936 605.0659949 558.2034595 588.9885353 535.9776779 533.2063569 511.8171023 410.4439055 1.539183333 1.234285337 1.4884426 1.474174636 1.359999386 1.43500373 1.305848791 1.299096782 1.246984291 1 8.681041255 -9.431620255 1.089406727 0.993518287 1.40358918 0.402601385 0.116547833 0.221844077 0.458821603 0.071178085 0.016736775 3.70E-10 9.431620255 0.410070893 SESELIDELSEDFDRSECK ddPTM_HeLa_Curcumin_4h_R1 1 SESELIDELSEDFDRSECK 19 1 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;P20810-8;B7Z574;P20810-4;E7ES10;P20810;E9PDE4;P20810-2;E7EVY3;E9PCH5;P20810-3;E7EQ12;E7EQA0;H0Y7F0;A0A0A0MR45;H0Y9H6;H0YD33;D6RC54 P20810-6 CAST Calpastatin 0 0 188.44 2.19E-09 16782000 1677.9 1328.7 1126 1471.1 1274.5 1692.3 1356.4 1115.3 1634.3 1393.7 FALSE FALSE TRUE 1545.092444 1443.546907 1167.730551 1465.012978 1259.30242 1341.297904 1394.456933 1455.349836 1455.021379 1442.130971 1.071395369 1.000981836 0.809725728 1.015866802 0.873223338 0.930080506 0.96694195 1.009166203 1.008938444 1 10.49398648 -6.987584821 24.99923516 1.033844704 0.9338264 0.336821939 0.05980546 174.6652682 351705.2614 0.0094488 0.012413815 1.03E-07 6.987584821 -0.100018304 SESGGLGVSMVEY(ph)VLSSSPADKLDSR ddPTM_HeLa_Curcumin_4h_R1 1 SESGGLGVSMVEYVLSSSPADKLDSR 26 1 C9JW01;A0A0A0MR59;Q8TB72-2;Q8TB72-4;Q8TB72-3;Q8TB72 C9JW01 PUM2 Pumilio homolog 2 1 0 SESGGLGVS(0.004)MVEY(0.551)VLS(0.147)S(0.147)S(0.147)PADKLDS(0.003)R 48.597 0.0083725 2703200 658.74 466.72 827.09 775.89 700.64 775.06 666.73 513.49 773.92 744.12 TRUE FALSE FALSE 606.6000339 507.0611971 857.742683 772.6795728 692.2853256 614.3038193 685.4366494 670.0507372 689.0229123 769.9781146 0.787814644 0.658539753 1.113983199 1.003508487 0.899097406 0.797819844 0.890202769 0.870220496 0.894860385 1 9.58867363 -9.594892594 1.431497199 0.999057249 0.867984411 0.019087276 0.120544552 0.679454969 2.52634303 0.083408848 0.019945558 2.54E-10 9.594892594 -0.131072837 SESGGLGVSMVEYVLS(ph)SSPGDSCLRK ddPTM_HeLa_Curcumin_4h_R1 1 SESGGLGVSMVEYVLSSSPGDSCLRK 26 1 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;H0YEH2 Q5T1Z4 PUM1 Pumilio homolog 1 1 0 SESGGLGVSMVEY(0.003)VLS(0.651)S(0.171)S(0.171)PGDS(0.003)CLRK 72.231 0.00021916 5942400 1614.4 1340.8 1248.8 1329.9 1444.1 1645.1 903.28 648.28 1699.2 1449.8 TRUE FALSE FALSE 1486.618536 1456.692778 1295.081627 1324.397226 1426.880051 1303.887716 928.6236057 845.9375877 1512.802011 1500.180442 0.990959817 0.971011711 0.863283903 0.882825285 0.95113895 0.869153923 0.61900794 0.563890559 1.008413367 1 10.55092032 -3.856081289 0.541996383 0.99157167 1.89E-16 0.880945244 0.051681424 1.253561856 0.182924259 0.010230359 0.863700424 0.00013929 3.856081289 -0.99157167 ETSFGS(ph)SENITMTSLSK ddPTM_HeLa_Curcumin_4h_R1 1 ETSFGSSENITMTSLSK 17 0 Q9UMZ2-6;Q9UMZ2-9;Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2;A0A087WZS7 Q9UMZ2-6 SYNRG Synergin gamma 1 0 ETS(0.001)FGS(0.689)S(0.13)ENIT(0.159)MT(0.018)S(0.003)LSK 91.657 0.0043806 41060000 6491.8 5334.2 5963.6 6294.7 5896 7220.1 5282.7 1914.8 6582.2 5550 TRUE FALSE FALSE 5977.96718 5795.264479 6184.616262 6268.654199 5825.694051 5722.569873 5430.918344 2498.613705 5860.149128 5742.862087 1.040938663 1.009124787 1.076922303 1.091555762 1.014423464 0.996466533 0.945681485 0.435081614 1.020423099 1 12.4875542 -4.215938978 2.57813084 1.026693744 0.268620285 0.971474356 0.030454382 0.07579402 0.575454749 0.004810325 0.130157063 6.08E-05 4.215938978 -0.758073459 down QTETSVNASRS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 1 QTETSVNASRSPEK 14 1 U3KQJ0;H0YG46;J3KNE4;A0A0A0MTP3;Q99550-2;Q99550 U3KQJ0 MPHOSPH9 M-phase phosphoprotein 9 1 0 QTETSVNAS(0.004)RS(0.996)PEK 96.135 0.0030588 16515000 2682.5 2317.1 2020.8 2256.7 2392.3 2873 1914 518.99 3095.7 2381.7 TRUE FALSE FALSE 2470.177294 2517.379799 2095.692626 2247.362373 2363.773385 2277.107415 1967.701689 677.2276619 2756.109455 2464.463898 1.002318312 1.021471567 0.850364506 0.9119072 0.959143036 0.923976779 0.79842991 0.274797153 1.118340365 1 11.26705813 -4.215122058 1.773814147 0.980525912 1.09E-12 0.907784477 0.067140017 0.17871351 0.505205226 0.008179774 0.304168059 6.09E-05 4.215122058 -0.980525912 down RGS(ph)FDATGSGFSMTFSSSSYSSSGYGR ddPTM_HeLa_Curcumin_4h_R1 1 RGSFDATGSGFSMTFSSSSYSSSGYGR 27 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 RGS(0.389)FDAT(0.178)GS(0.353)GFS(0.053)MT(0.024)FS(0.001)SSSYSSSGYGR 44.11 0.017736 6043200 518.44 412.23 356.11 421.66 313.87 627.64 505.58 637.18 325.2 343.93 TRUE FALSE FALSE 477.4049269 447.8613243 369.3077499 419.9152826 310.1273052 497.460389 519.7652141 831.4532488 289.5263736 355.8815419 1.341471447 1.258456176 1.037726621 1.17992993 0.871434083 1.397825766 1.460500624 2.336320238 0.813547036 1 8.475253298 -4.066461113 1.425507116 1.150298546 3.287044879 0.814214626 0.177564663 0.578072956 0.735559785 0.024198829 1.999310376 8.58E-05 4.066461113 2.136746333 up SESLIDASEDS(ph)QLEAAIR ddPTM_HeLa_Curcumin_4h_R1 3 SESLIDASEDSQLEAAIR 18 0 C9JAT7;O94888 C9JAT7 UBXN7 UBX domain-containing protein 7 1 0 SESLIDASEDS(1)QLEAAIR;SESLIDASEDS(1)QLEAAIR;SES(0.003)LIDAS(0.003)EDS(0.994)QLEAAIR ;; 190.37 7.46E-09 55567100 5845.2 6232.5 6611.2 6143.4 5662 7843.5 7004.7 5102.02 7252 5968.9 TRUE FALSE FALSE 5382.546252 6771.209529 6856.216888 6117.980239 5594.484348 6216.669686 7201.23303 6657.602411 6456.473744 6176.318831 0.871481282 1.096318003 1.110081438 0.990554472 0.905795912 1.006533156 1.165942567 1.077924018 1.045359529 1 12.59253151 -7.255196758 24.84698802 0.939310605 1.047629086 0.126373193 0.081104999 486.7691078 1937447.518 0.014505013 0.017531123 5.56E-08 7.255196758 0.108318481 SESPKEPEQLR ddPTM_HeLa_Curcumin_4h_R1 3 SESPKEPEQLR 11 1 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8W646 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 0 0 ;; ;; 104.07 0.0050354 38421000 8916.3 7065.8 7407.4 8016.3 9077 9536.4 8002.5 7987.6 9090.1 7737.5 FALSE FALSE TRUE 8210.565447 7676.536267 7681.92476 7983.130675 8968.762703 7558.443143 8227.028612 10422.98247 8092.938772 8006.377549 1.025503156 0.958802682 0.959475707 0.997096455 1.12020232 0.9440528 1.027559413 1.301834994 1.010811534 1 12.96693393 -4.265222157 4.880098371 1.007076966 1.316674363 0.784544751 0.04679435 0.054977516 3.860650017 0.006137835 0.057240482 5.43E-05 4.265222157 0.309597397 SESQESLVT(ph)SPSKPK ddPTM_HeLa_Curcumin_4h_R1 1 SESQESLVTSPSKPK 15 1 E7EWD6;Q76L83;Q76L83-2;A0A5F9ZHN2 E7EWD6 ASXL2 Putative Polycomb group protein ASXL2 1 0 SESQESLVT(0.494)S(0.494)PS(0.012)KPK 84.94 0.0096634 23956000 7137.4 5955.4 6843.9 6186.3 6298.3 7669 5912.7 2566.5 6429.8 5740.7 TRUE FALSE FALSE 6572.467259 6470.158239 7097.540955 6160.70273 6223.196886 6078.362953 6078.594449 3349.014035 5724.467027 5940.188898 1.106440784 1.089217591 1.194834218 1.03712236 1.047642927 1.023260886 1.023299857 0.563789148 0.963684342 1 12.53629309 -4.250014078 3.688685142 1.061115552 0.503681077 0.857029167 0.06018294 0.077428495 1.907017066 0.008450014 0.11935612 5.62E-05 4.250014078 -0.557434475 SESS(ph)DFEVVPK ddPTM_HeLa_Curcumin_4h_R1 2 SESSDFEVVPK 11 0 E7EPN9;Q9Y520-6;Q9Y520-4;Q9Y520-5;Q9Y520;Q9Y520-7;Q9Y520-3;Q9Y520-2 E7EPN9 PRRC2C Protein PRRC2C 1 0 S(0.002)ES(0.116)S(0.883)DFEVVPK;SES(0.326)S(0.674)DFEVVPK ; 156.01 0.0004242 40305000 12643.7 9448 11713.8 12850.2 12554.6 13225.2 13334.8 9116.7 11317.5 11597.4 TRUE FALSE FALSE 11642.9378 10264.64302 12147.92373 12797.02928 12404.89459 10482.14444 13708.9386 11896.33986 10075.99856 12000.40879 0.970211766 0.85535778 1.012292493 1.06638278 1.033706002 0.873482281 1.142372634 0.991327885 0.839637944 1 13.55079593 -6.54597051 24.98043749 0.973750852 1.022502611 0.14875161 0.085031444 430.3747848 465573.1035 0.011274971 0.015945681 2.84E-07 6.54597051 0.048751759 SESSTSAFST(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 4 SESSTSAFSTPTR 13 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 0 SESSTSAFS(0.038)T(0.842)PT(0.121)R;SESST(0.002)S(0.001)AFS(0.1)T(0.797)PT(0.1)R;SESSTS(0.002)AFS(0.082)T(0.914)PT(0.003)R;SESSTSAFS(0.078)T(0.898)PT(0.025)R ;;; 176.87 0.00059804 89353000 16590.6 11644.6 15085.8 15890.3 15393.4 17247.1 13840.9 5280.8 16161.2 12193.2 TRUE FALSE FALSE 15277.4365 12651.10734 15644.89302 15824.55015 15209.84376 13669.85705 14229.2384 6890.89161 14388.35679 12616.91279 1.210869628 1.002710215 1.239993751 1.25423314 1.205512316 1.083454984 1.127790818 0.546163053 1.140402334 1 13.62307132 -4.261088526 24.69488722 1.122044062 0.546162858 0.803027328 0.087884869 9.617400593 676591.5266 0.014589779 0.114727141 5.48E-05 4.261088526 -0.575881204 SESVEGFLS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 3 SESVEGFLSPSR 12 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 0 SESVEGFLS(0.995)PS(0.005)R;SESVEGFLS(1)PSR;SESVEGFLS(0.999)PS(0.001)R ;; 215.77 3.27E-13 212417000 5430.3 4300.2 4933.4 4988.6 4973.1 6522.2 4159.9 2673.06 5821.7 4535.8 TRUE FALSE FALSE 5000.486025 4671.890127 5116.236144 4967.958495 4913.799031 5169.4222 4276.615598 3488.063689 5183.074075 4693.418712 1.065425084 0.995413027 1.090087303 1.058494628 1.04695518 1.101419353 0.911194134 0.743181869 1.10432808 1 12.19642346 -4.446013633 3.013275053 1.039931934 0.741441813 0.853734698 0.040419849 0.076801082 1.187029966 0.005396225 0.043253418 3.58E-05 4.446013633 -0.298490122 SESVVSGLDS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 2 SESVVSGLDSPAK 13 0 H7BYJ3;O14578;O14578-4;O14578-2 H7BYJ3 CIT Citron Rho-interacting kinase 1 0 SESVVSGLDS(1)PAK;S(0.005)ESVVSGLDS(0.994)PAK ; 201.3 8.65E-09 66086000 10844.6 8883.4 10710.9 10167.4 10767 13640.2 11649.7 4620.2 10349.5 9398.6 TRUE FALSE FALSE 9986.238467 9651.241512 11107.85538 10125.32999 10638.61056 10811.06876 11976.55923 6028.877711 9214.185743 9725.20065 1.026841381 0.992395104 1.14217236 1.041143556 1.09392196 1.111655086 1.231497391 0.619923221 0.947454564 1 13.2475123 -4.245065841 24.95780525 1.045046487 0.619922887 0.726836735 0.081052518 1324.166772 2018365.443 0.010972582 0.399105281 5.69E-05 4.245065841 -0.425123599 SESVVY(ph)ADIR ddPTM_HeLa_Curcumin_4h_R1 1 SESVVYADIR 10 0 O95297-4;O95297-2;O95297;O95297-5 O95297-4 MPZL1 Myelin protein zero-like protein 1 1 0 SESVVY(1)ADIR 146.23 0.006652 7061200 1717.8 1680.1 1446.8 1585.6 1660.1 4539.2 1510.5 502.23 2624.1 2090 TRUE FALSE FALSE 1581.834317 1825.320358 1500.419681 1579.039207 1640.304392 3597.718753 1552.880565 655.357615 2336.242795 2162.627344 0.731441005 0.844029075 0.693794835 0.730148544 0.758477597 1.663587008 0.718052774 0.303037699 1.080279874 1 11.07856937 -9.497603191 1.249208471 0.999805302 0.814287397 0.074031166 0.321348807 1.410594047 3.945770936 0.22202741 0.054148514 3.18E-10 9.497603191 -0.185517905 SET(ph)PPHWR ddPTM_HeLa_Curcumin_4h_R1 1 SETPPHWR 8 0 Q13427;E9PG73;C9JM79 Q13427 PPIG Peptidyl-prolyl cis-trans isomerase G 1 0 S(0.001)ET(0.999)PPHWR 94.409 0.01741 8731600 3721.7 3162 3598.9 4267.8 3849.4 4559.4 3963.3 4851.3 4581.2 3691.8 TRUE FALSE FALSE 3427.123518 3435.30919 3732.2784 4250.140974 3803.498419 3613.729045 4074.499531 6330.439037 4078.653822 3820.089775 0.89713167 0.899274465 0.977013269 1.112576202 0.995656815 0.945980136 1.066597847 1.657144049 1.067685332 1 11.89939083 -4.254006379 2.99509941 0.963217558 1.777994099 0.898056738 0.066928047 0.084282734 1.081145629 0.009482159 0.164915766 5.57E-05 4.254006379 0.814776541 SET(ph)SPVAPR ddPTM_HeLa_Curcumin_4h_R1 2 SETSPVAPR 9 0 A0A2R8YGD3;Q9Y4G8;A0A2R8Y661;H0Y8H7;H0Y8T6 A0A2R8YGD3 RAPGEF2 Rap guanine nucleotide exchange factor 2 1 0 S(0.001)ET(0.932)S(0.067)PVAPR;S(0.001)ET(0.633)S(0.365)PVAPR ; 150.81 0.0047621 232070000 6791.7 6081.4 6597 6827.1 6241.7 6604.5 5367.8 3889.1 7098.7 5791.7 TRUE FALSE FALSE 6254.129778 6607.049118 6841.490623 6798.851269 6167.271804 5234.652252 5518.406021 5074.868687 6319.99037 5992.961144 1.04357923 1.102468205 1.141587682 1.134472777 1.029085899 0.873466743 0.920814584 0.846804871 1.054568888 1 12.5490533 -5.292591547 5.706990007 1.046225429 0.883985615 0.741840911 0.050284818 0.096751147 9.745837205 0.008853037 0.020619303 5.10E-06 5.292591547 -0.162239814 SETAPAAPAAPAPAEKT(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 3 SETAPAAPAAPAPAEKTPVK 20 1 P10412 P10412 HIST1H1E Histone H1.4 1 0 SETAPAAPAAPAPAEKT(1)PVK;SETAPAAPAAPAPAEKT(1)PVK;SETAPAAPAAPAPAEKT(1)PVK ;; 120.24 9.34E-05 81819000 14154.3 10396.7 12890.6 13497.5 14333.2 18844.4 14304.1 6444.8 15172.3 10987.2 TRUE FALSE FALSE 13033.97222 11295.34442 13368.33698 13441.65092 14162.28595 14935.85902 14705.43455 8409.789852 13507.93665 11369.00438 1.14644799 0.993520984 1.175858195 1.182306776 1.245692716 1.313735004 1.293467225 0.739712078 1.188137166 1 13.4728183 -6.729985921 21.58195853 1.065415711 1.176705699 0.040424138 0.161009279 79.60082018 54617.18136 0.024151067 0.034149823 1.86E-07 6.729985921 0.111289988 SETAPAAPAAPAPAEKT(ph)PVKK ddPTM_HeLa_Curcumin_4h_R1 1 SETAPAAPAAPAPAEKTPVKK 21 2 P10412 P10412 HIST1H1E Histone H1.4 1 0 SETAPAAPAAPAPAEKT(1)PVKK 69.935 0.0013995 33799000 3793.8 2612.3 3246 3819 3696 4606.4 3584.9 1265.4 4516.9 3462.1 TRUE FALSE FALSE 3493.516727 2838.095572 3366.299615 3803.19799 3651.927614 3650.980715 3685.482646 1651.214635 4021.407371 3582.407717 0.975186802 0.792231314 0.93967518 1.06163181 1.019405914 1.019141595 1.028772529 0.460923146 1.122543185 1 11.80671383 -4.258367408 24.97187525 0.982800391 0.460922952 0.787362792 0.083094337 86.43611516 702597.8398 0.009986392 0.094704464 5.52E-05 4.258367408 -0.521877439 SETAPAETATPAPVEKS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 3 SETAPAETATPAPVEKSPAK 20 1 P16401 P16401 HIST1H1B Histone H1.5 1 0 SETAPAETAT(0.017)PAPVEKS(0.982)PAK;SETAPAET(0.002)AT(0.22)PAPVEKS(0.778)PAK;SETAPAET(0.004)AT(0.128)PAPVEKS(0.868)PAK ;; 115.96 6.17E-05 373200000 13331.2 8411.22 11088.1 13667.7 12037.51 15400.7 11802.13 7569.3 15030.4 10813.9 TRUE FALSE FALSE 12276.02145 9138.248377 11499.03474 13611.14668 11893.97056 12206.42122 12133.266 9877.144725 13381.60272 11189.68222 1.097084011 0.816667372 1.027646229 1.216401539 1.06294087 1.090863974 1.084326236 0.882701093 1.195887646 1 13.44988144 -9.779876478 1.754948657 0.9998615 1.048838788 0 0.123738298 1.434431035 7.977496373 0.07938793 0.016689033 1.66E-10 9.779876478 0.048977288 SETAPAETATPAPVEKS(ph)PAKK ddPTM_HeLa_Curcumin_4h_R1 1 SETAPAETATPAPVEKSPAKK 21 2 P16401 P16401 HIST1H1B Histone H1.5 1 0 SETAPAETAT(0.003)PAPVEKS(0.997)PAKK 66.977 0.0011345 7146500 6324.6 3732.4 4994.6 6409.5 5199.6 6690.4 5020.4 3686.1 7337.4 5232.3 TRUE FALSE FALSE 5824.001236 4055.012025 5179.70427 6382.979187 5137.598166 5302.735624 5161.258912 4809.974921 6532.505577 5414.122036 1.075705571 0.748969454 0.956702534 1.178950002 0.948925446 0.97942669 0.953295637 0.888412727 1.206567849 1 12.40251169 -2.372848704 0.526388097 1.017035816 7.32E-15 0.106556972 0.120523352 41.47815508 1.600603242 0.020585726 40.13225383 0.004237906 2.372848704 -1.017035816 YEAQGDK(ac)AK ddPTM_HeLa_Curcumin_4h_R1 2 YEAQGDKAK 9 1 O75351;K7EKZ3;K7EL71 O75351 VPS4B Vacuolar protein sorting-associated protein 4B 0 1 ; YEAQGDK(1)AK;YEAQGDK(1)AK 132.78 0.00045396 6957500 5829.3 5320.7 6169.6 5739.4 6335.5 8298 7427.4 11302.3 5322.7 4678.2 FALSE TRUE FALSE 5367.904754 5780.597599 6398.250803 5715.651884 6259.9533 6576.901262 7635.792854 14748.31924 4738.813127 4840.767102 1.108895479 1.194149084 1.321743159 1.180732674 1.293173823 1.358648562 1.577393147 3.04669052 0.978938467 1 12.24101997 -1.727163793 0.88333007 1.097082148 200 0.960663688 0.113491797 25.53593328 0.246685594 0.019407029 9990.974315 0.018742875 1.727163793 198.9029179 up KYGGSVGSQPPPVAPEPGPVPS(ph)SPSQEPPTKR ddPTM_HeLa_Curcumin_4h_R1 2 KYGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR 32 2 E9PS08;A0A087WTZ5;E9PJ81;E9PRQ7;Q04323;Q04323-2 E9PS08 UBXN1 UBX domain-containing protein 1 1 0 KYGGSVGSQPPPVAPEPGPVPS(0.48)S(0.48)PS(0.032)QEPPT(0.007)KR;KYGGSVGSQPPPVAPEPGPVPS(0.472)S(0.472)PS(0.044)QEPPT(0.012)KR ; 115.9 4.47E-14 145798000 11992.6 9767.9 9841.3 10794 10303.3 14967.2 13495 17454.2 12118.8 9988.6 TRUE FALSE FALSE 11043.37306 10612.19375 10206.02724 10749.33729 10180.43988 11862.834 13873.63338 22775.90523 10789.39796 10335.70311 1.068468487 1.026751024 0.987453599 1.040019936 0.984977971 1.147752977 1.342301848 2.2036145 1.043895887 1 13.33534891 -4.062945179 1.473227817 1.027403526 3.162130944 0.990380783 0.034765915 0.131491215 0.17845213 0.005549872 0.469180369 8.65E-05 4.062945179 2.134727418 up TRS(ph)LPITIEMLK ddPTM_HeLa_Curcumin_4h_R1 1 TRSLPITIEMLK 12 1 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 0 T(0.063)RS(0.929)LPIT(0.008)IEMLK 82.942 0.0095596 13547000 2541.5 1911.1 2313 2258.7 2040.1 3794.5 3356.5 4593.3 2096.9 2505.2 TRUE FALSE FALSE 2340.337593 2076.286968 2398.721815 2249.354098 2015.77314 3007.477927 3450.674356 5993.776025 1866.875316 2592.255514 0.902819024 0.800957682 0.925341581 0.867720827 0.777613599 1.160178042 1.331147465 2.31218566 0.720174113 1 11.33999221 -4.060678383 1.358140672 0.924263416 3.459889338 0.942606233 0.10696031 0.289901712 0.328890568 0.01358635 1.143481072 8.70E-05 4.060678383 2.535625922 up SETS(ph)PVAPR ddPTM_HeLa_Curcumin_4h_R1 1 SETSPVAPR 9 0 A0A2R8YGD3;Q9Y4G8;A0A2R8Y661;H0Y8H7;H0Y8T6 A0A2R8YGD3 RAPGEF2 Rap guanine nucleotide exchange factor 2 1 0 S(0.001)ET(0.137)S(0.861)PVAPR 122.94 0.0054741 165880000 2919.2 2652.5 3314.2 2525.1 2845.5 3288.1 2255.2 1676.1 3534.4 2451.2 TRUE FALSE FALSE 2688.14224 2881.770281 3437.027167 2514.651805 2811.569271 2606.110995 2318.474842 2187.135174 3146.685163 2536.379018 1.059834599 1.136174941 1.355092099 0.991433768 1.108497291 1.027492728 0.914088481 0.86230613 1.240621035 1 11.30855463 -4.736137729 2.67632745 1.06437942 0.869497076 0.326767358 0.115069045 0.266256667 3.704294473 0.015405297 0.073645519 1.84E-05 4.736137729 -0.194882344 SETSGPQIK ddPTM_HeLa_Curcumin_4h_R1 2 SETSGPQIK 9 0 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 0 0 ; ; 129.42 0.0006562 12952200 6624.6 5089.1 5902.1 6178.6 5986 7497.8 5839.9 5900 7169.3 5810.8 FALSE FALSE TRUE 6100.25592 5528.979127 6120.837018 6153.03459 5914.62086 5942.671762 6003.751877 7698.88284 6382.845727 6012.724867 1.014557635 0.919546337 1.017980558 1.023335464 0.983683935 0.988349192 0.998507666 1.280431586 1.061556261 1 12.55380323 -4.261276672 24.94521955 0.999819037 1.28043167 0.856888494 0.034276715 2.709167976 414983.6194 0.003799365 0.02955802 5.48E-05 4.261276672 0.280612633 SETSGPQIKELT(ph)DEEAER ddPTM_HeLa_Curcumin_4h_R1 1 SETSGPQIKELTDEEAER 18 1 Q9Y266;A0A0A0MSS4;A0A0A0MSU9 Q9Y266 NUDC Nuclear migration protein nudC 1 0 SETSGPQIKELT(1)DEEAER 88.627 0.0027405 12920000 1922.4 1609.7 1384.7 2064.2 1356.2 1980.5 1286.4 1404.6 2492.6 1952.2 TRUE FALSE FALSE 1770.240011 1748.835295 1436.0182 2055.658887 1340.028201 1569.721975 1322.492922 1832.856074 2219.168016 2020.038805 0.876339607 0.865743416 0.710886443 1.017633366 0.663367554 0.777075159 0.65468689 0.907337062 1.098576924 1 10.98016729 -7.879086157 0.322560629 1.027594594 0.747024805 0.438311318 0.109574067 1.063987534 0.321793134 0.118781365 0.076124969 1.32E-08 7.879086157 -0.280569789 SETSS(ph)NPS(ph)SPEICPNK ddPTM_HeLa_Curcumin_4h_R1 1 SETSSNPSSPEICPNK 16 0 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 2 0 SET(0.006)S(0.069)S(0.925)NPS(0.5)S(0.5)PEICPNK 155.09 0.00074382 18503000 5264.2 4484.5 5556.1 4961.9 5351.3 6605.6 6065.5 6122.1 5115 4239.6 TRUE FALSE FALSE 4847.533015 4872.120197 5762.013954 4941.368973 5287.489243 5235.5241 6235.681606 7988.700107 4553.897297 4386.925784 1.104995446 1.110600096 1.313451432 1.126385359 1.205283495 1.193438038 1.421424002 1.821024676 1.038061166 1 12.09899458 -1 0.500443073 1.063700436 24.4829627 0.878285872 0.079945339 23.38976708 0.224322962 0.017258439 579.567211 0.1 1 23.41926226 SETSS(ph)NPSS(ph)PEICPNK ddPTM_HeLa_Curcumin_4h_R1 1 SETSSNPSSPEICPNK 16 0 A0A1B0GV05;Q684P5-3;Q684P5-2;Q684P5 A0A1B0GV05 RAP1GAP2 Rap1 GTPase-activating protein 2 2 0 SET(0.004)S(0.061)S(0.935)NPS(0.028)S(0.972)PEICPNK 186.08 1.19E-05 21858000 6919.3 6940.1 6605.6 6590 7094.5 8984.7 6931.7 8250.6 6700.1 6551.6 TRUE FALSE FALSE 6371.630104 7539.97132 6850.409347 6562.732326 7009.902721 7121.171942 7126.184846 10766.16996 5965.115793 6779.267612 0.939869978 1.112210308 1.010494015 0.968059192 1.034020653 1.050433815 1.051173261 1.588102222 0.879905638 1 12.72691371 -4.202405519 2.66854759 0.992311291 1.762842347 0.893878856 0.060394798 0.12295001 0.990016186 0.00763082 0.222694518 6.27E-05 4.202405519 0.770531057 LLPDPGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 LLPDPGSPR 9 0 A6ND36 A6ND36 FAM83G Protein FAM83G 1 0 LLPDPGS(1)PR;LLPDPGS(1)PR;LLPDPGS(1)PR ;; 117.14 0.006977 69475000 22305 17648.5 18742.3 19848.5 19037.9 19735.4 14185.2 4557.6 20449.4 16171.1 TRUE FALSE FALSE 20539.53571 19173.9577 19436.90613 19766.37217 18810.88548 15642.05558 14583.19853 5947.191259 18206.15198 16733.04452 1.22748348 1.145873823 1.161588144 1.181277689 1.124175906 0.934800332 0.871520931 0.355415971 1.08803583 1 14.03041234 -4.21487735 1.257535113 1.12197225 1.40E-16 0.918129255 0.06953643 0.423891677 0.520038879 0.014049307 0.629841404 6.10E-05 4.21487735 -1.12197225 down AASSPDGFFWTQGS(ph)PKPGTAS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 AASSPDGFFWTQGSPKPGTASPK 23 1 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 2 0 AAS(0.001)S(0.002)PDGFFWT(0.477)QGS(0.523)PKPGT(0.054)AS(0.944)PK 70.051 0.0015849 0 2125 1683.4 1766.9 1706.2 1866.5 1987 1396.5 463.02 1948.9 1835.8 TRUE FALSE FALSE 1956.804008 1828.905595 1832.382868 1699.140196 1844.243207 1574.873802 1435.682032 604.1926665 1735.110546 1899.593913 1.030117013 0.962787668 0.964618204 0.89447549 0.970861821 0.829058143 0.755783655 0.31806412 0.9134113 1 10.89147532 -4.213398096 1.026164084 0.998795033 4.69E-23 0.923555592 0.054723326 0.317932625 0.242778609 0.007475436 0.355299268 6.12E-05 4.213398096 -0.998795033 down SEVDMLK ddPTM_HeLa_Curcumin_4h_R1 2 SEVDMLK 7 0 P07355;A6NMY6;P07355-2 P07355;P07355-2 ANXA2;ANXA2P2 Annexin A2;Putative annexin A2-like protein 0 0 ; ; 148.33 0.0014066 26323000 12988.1 11516.8 10463.8 13255.9 10963.9 14545.9 13089.9 11499.8 16049.4 10616.7 FALSE FALSE TRUE 11960.07818 12512.26087 10851.59763 13201.0506 10833.16265 11528.91637 13457.16736 15006.03608 14288.82097 10985.62953 1.088702121 1.138966214 0.987799343 1.201665372 0.986121243 1.04945432 1.224979171 1.365969609 1.300682945 1 13.42332993 -4.547241643 2.614743904 1.053301255 1.363344729 0.36744329 0.102122392 0.127913667 1.562263457 0.009337111 0.065213931 2.84E-05 4.547241643 0.310043474 SEVLSESS(ph)ELLQQELEELRK ddPTM_HeLa_Curcumin_4h_R1 1 SEVLSESSELLQQELEELRK 20 1 H0YJ97;Q15643-2;Q15643 H0YJ97 TRIP11 Thyroid receptor-interacting protein 11 1 0 SEVLS(0.006)ES(0.122)S(0.872)ELLQQELEELRK 156.41 6.94E-06 3581800 1264.6 1205.9 1381 1654.7 1526.6 1686.2 923.6 692.87 1476 1451 TRUE FALSE FALSE 1164.505576 1310.132623 1432.181075 1647.85329 1508.396292 1336.463113 949.5137303 904.1228734 1314.086493 1501.422142 0.775601707 0.872594446 0.953883012 1.097528299 1.004645029 0.890131479 0.632409569 0.602177661 0.875227863 1 10.55211395 -4.764361429 4.616834308 0.91779099 0.609379265 0.68848435 0.08489564 0.104343806 5.542735626 0.015644295 0.056494345 1.72E-05 4.764361429 -0.308411725 SEVQAIIESTPELDMDKDLS(ph)GYKGSSTPTK ddPTM_HeLa_Curcumin_4h_R1 1 SEVQAIIESTPELDMDKDLSGYKGSSTPTK 30 2 O60271-3;O60271;A0A087X2D8;O60271-5;O60271-9;O60271-4;O60271-2;H0YBE9 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 SEVQAIIES(0.001)T(0.001)PELDMDKDLS(0.239)GY(0.121)KGS(0.191)S(0.191)T(0.191)PT(0.064)K 50.865 0.0034006 25137000 613.07 630.98 688.56 853.91 823.8 727.92 549.06 653.7 745.01 359.58 TRUE FALSE FALSE 564.5448626 685.5190996 714.0786393 850.3767467 813.976723 576.9411867 564.4651459 853.0101207 663.2842669 372.0753782 1.517286269 1.84241995 1.919177352 2.285495887 2.187666184 1.55060297 1.517072021 2.292573416 1.782661003 1 8.539451114 -7.89359285 0.760286315 1.079984848 1.951567282 0.225507946 0.341523111 0.266637221 0.338338886 0.091282773 0.071197735 1.28E-08 7.89359285 0.871582434 SEVQQPVHPKPLS(ph)PDSR ddPTM_HeLa_Curcumin_4h_R1 3 SEVQQPVHPKPLSPDSR 17 1 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;F8VRN8;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 S(0.006)EVQQPVHPKPLS(0.948)PDS(0.046)R;SEVQQPVHPKPLS(0.914)PDS(0.086)R;SEVQQPVHPKPLS(0.826)PDS(0.174)R ;; 111.57 0.00047116 1187723000 9123.6 7599.5 7410.5 7921 8029.5 9052.5 6631.7 6426.7 9240 7445.2 TRUE FALSE FALSE 8401.457433 8256.366917 7685.139649 7888.225001 7933.753457 7174.909457 6817.767654 8386.171245 8226.395117 7703.920146 1.090543162 1.071709826 0.997562216 1.023923516 1.029833294 0.931332273 0.884973822 1.088558953 1.067819365 1 12.91137703 -5.363950335 5.560055175 1.040633632 0.960316457 0.25733299 0.05566864 0.222637189 9.912921795 0.008261568 0.018767858 4.33E-06 5.363950335 -0.080317174 SEVS(ph)SPIQR ddPTM_HeLa_Curcumin_4h_R1 1 SEVSSPIQR 9 0 A0JP02;B4DJX4;Q9HAU0-8;Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;Q9HAU0-5;H0YG48;Q9HAU0-3 A0JP02 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 0 S(0.012)EVS(0.494)S(0.494)PIQR 109.66 0.0092587 121140000 6113.2 5585.7 5237.4 5378.2 4921.6 6953.2 5312.3 2233.1 6167 5060.7 TRUE FALSE FALSE 5629.333769 6068.503019 5431.502651 5355.946433 4862.913134 5511.027941 5461.348841 2913.96191 5490.495529 5236.558948 1.075006283 1.158872282 1.037227444 1.022798843 0.92864669 1.052413999 1.042927024 0.556465026 1.048493024 1 12.35440338 -4.261080044 24.83821249 1.037978858 0.55646487 0.875664262 0.054732596 7.117887086 491790.3893 0.0081226 0.063971787 5.48E-05 4.261080044 -0.481513988 SEWLDPS(ph)QKSPLHVGETR ddPTM_HeLa_Curcumin_4h_R1 1 SEWLDPSQKSPLHVGETR 18 1 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 0 S(0.018)EWLDPS(0.75)QKS(0.23)PLHVGET(0.002)R 59.15 0.013234 91112000 1543.3 1299.9 1481.5 1120.9 1407.4 1366.5 812.8 880.62 1318.3 1232.3 TRUE FALSE FALSE 1421.146177 1412.257564 1536.405693 1116.262013 1390.617674 1083.072496 835.6049805 1149.116984 1173.685788 1275.122333 1.114517517 1.107546725 1.204908465 0.875415624 1.090575891 0.849387128 0.655313579 0.901181757 0.920449558 1 10.31641995 -5.149117736 3.987068327 1.059373343 0.772813423 0.518459861 0.107525739 0.114137881 3.153364326 0.013691097 0.037362017 7.09E-06 5.149117736 -0.28655992 SEWLDPSQKS(ph)PLHVGETR ddPTM_HeLa_Curcumin_4h_R1 2 SEWLDPSQKSPLHVGETR 18 1 O15164-2;O15164 O15164-2 TRIM24 Transcription intermediary factor 1-alpha 1 0 SEWLDPS(0.031)QKS(0.969)PLHVGETR;SEWLDPS(0.288)QKS(0.712)PLHVGETR ; 78.078 0.0027413 69328100 5713.7 4518.4 4898.5 5394.8 5545.4 5772.3 4173.2 3414 6051.5 4871.5 TRUE FALSE FALSE 5261.454616 4908.950362 5080.042719 5372.477747 5479.274727 4575.059913 4290.28876 4454.912884 5387.66559 5040.784262 1.043776988 0.97384655 1.007788164 1.06580196 1.08698854 0.907608752 0.85111533 0.883773765 1.068814952 1 12.2994325 -5.0983148 5.190072249 1.023620218 0.869847315 0.804042262 0.034935733 0.07034067 2.90999937 0.004883637 0.01294663 7.97E-06 5.0983148 -0.153772903 SFDLLVK ddPTM_HeLa_Curcumin_4h_R1 1 SFDLLVK 7 0 Q9HB71;Q9HB71-3 Q9HB71 CACYBP Calcyclin-binding protein 0 0 107.32 0.015659 2972900 3698.8 2997.2 3346.9 3479.9 3202.1 4005.4 3742.9 3248.5 3647.2 2910.8 FALSE FALSE TRUE 3406.036077 3256.264613 3470.939058 3465.501096 3163.917049 3174.63489 3847.915701 4238.952696 3247.111285 3011.950083 1.130840812 1.081115066 1.152389303 1.150583841 1.050454676 1.054013115 1.277549625 1.407378137 1.078076062 1 11.55648215 -4.594884284 3.132446214 1.075813742 1.392825881 0.829142023 0.047677611 0.08941409 1.666010883 0.008857587 0.047255107 2.54E-05 4.594884284 0.317012138 TTT(ph)SPFFSEDTFR ddPTM_HeLa_Curcumin_4h_R1 1 TTTSPFFSEDTFR 13 0 A0A5F9ZGT0;H0Y9K9;G5E9Z1;A0A590UJE4;A0A494C0H4;H0Y9M2;Q17R98-3;Q17R98-2;Q17R98;A0A5F9ZHK5 A0A5F9ZGT0 ZNF827 Zinc finger protein 827 1 0 T(0.001)TT(0.933)S(0.066)PFFSEDTFR 222.73 1.31E-13 14166000 4493.4 3836.1 3952.2 3948.6 3662.9 4522.5 3283.7 841.83 5314.9 3909.2 TRUE FALSE FALSE 4137.742649 4167.675391 4098.672009 3932.261739 3619.22231 3584.482521 3375.831784 1098.500092 4731.868767 4045.044409 1.022916495 1.03031635 1.013257605 0.972118311 0.894729932 0.886141698 0.834559882 0.271566881 1.169794022 1 11.98193983 -4.213346697 1.560496732 0.999804741 5.98E-36 0.900954048 0.072550545 0.192720042 0.395492705 0.007453618 0.303525202 6.12E-05 4.213346697 -0.999804741 down SFEVEEVET(ph)PNST(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 2 SFEVEEVETPNSTPPR 16 0 Q9UHD8;Q9UHD8-5;Q9UHD8-2;Q9UHD8-7;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 9-Sep Septin-9 2 0 SFEVEEVET(1)PNS(0.293)T(0.707)PPR;SFEVEEVET(1)PNS(0.325)T(0.675)PPR ; 175.27 0.00014384 29205000 6516.6 5866.1 6117.8 6004.1 7162 9535.4 8105.6 2876.43 6826 4923.8 TRUE FALSE FALSE 6000.804234 6373.139545 6344.53105 5979.256625 7076.597828 7557.650554 8333.021321 3753.440266 6077.204878 5094.901684 1.177805698 1.250885678 1.245270556 1.173576449 1.3889567 1.483375151 1.63556077 0.736705141 1.192801207 1 12.31483859 -7.897709821 0.488543562 1.003251244 1.324513728 0.061631519 0.228850575 0.957153518 0.559068941 0.120855073 0.080472746 1.27E-08 7.897709821 0.321262484 SFEVEEVETPNST(ph)PPRR ddPTM_HeLa_Curcumin_4h_R1 1 SFEVEEVETPNSTPPRR 17 1 Q9UHD8;Q9UHD8-5;Q9UHD8-2;Q9UHD8-7;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 9-Sep Septin-9 1 0 SFEVEEVETPNS(0.01)T(0.989)PPRR 181.69 6.69E-05 31629000 3798.6 3354.1 2940.2 3651.4 3614.6 5686 4634.6 2455.9 4256.6 3284.2 TRUE FALSE FALSE 3497.936802 3644.013458 3049.166398 3636.291474 3571.498256 4506.659506 4764.634403 3204.692604 3789.661629 3398.325706 1.029311816 1.072296706 0.897255491 1.070024415 1.050958197 1.326141134 1.402053486 0.943021029 1.115155508 1 11.73060842 -5.384383414 5.197858575 1.01458669 1.24039045 0.324594066 0.123696315 0.150991919 5.785110982 0.01563244 0.035596235 4.13E-06 5.384383414 0.22580376 SFGTRPLSSGFS(ph)PEEAQQQDEEFEK ddPTM_HeLa_Curcumin_4h_R1 1 SFGTRPLSSGFSPEEAQQQDEEFEK 25 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 S(0.006)FGT(0.016)RPLS(0.344)S(0.143)GFS(0.491)PEEAQQQDEEFEK 75.156 0.00017605 110840000 3280.9 2636.9 2505.1 2956.1 3135.1 3326.4 2070.1 1671 3257.5 2626.8 TRUE FALSE FALSE 3021.213303 2864.821886 2597.94121 2943.868441 3097.71598 2636.467144 2128.181435 2180.480208 2900.1604 2718.081104 1.111524339 1.053986903 0.955799739 1.083068653 1.139670179 0.969973685 0.782972013 0.802213077 1.066988176 1 11.40837279 -4.879563842 3.716164752 1.053928862 0.791126998 0.813980987 0.050151333 0.077205058 2.001112035 0.008206011 0.028087797 1.32E-05 4.879563842 -0.262801864 SFINY(ph)QFMS(ph)S(ph)HIK ddPTM_HeLa_Curcumin_4h_R1 1 SFINYQFMSSHIK 13 0 Q86T24 Q86T24 ZBTB33 Transcriptional regulator Kaiso 3 0 S(0.041)FINY(0.961)QFMS(0.998)S(1)HIK 75.509 0.0057775 0 885.63 733.89 823.37 780.28 692.6 1157.4 742.73 807.55 916.6 807.5 TRUE FALSE FALSE 815.531451 797.3241814 853.8848165 777.0514081 684.3411974 917.3421934 763.5690048 1053.768277 816.0512732 835.5605649 0.97602913 0.954238645 1.021930489 0.929976163 0.819020459 1.097876362 0.913840405 1.261151282 0.976651254 1 9.706600594 -4.253529422 24.67502843 0.976703567 1.261151449 0.613850314 0.069839368 402.1763181 1254549.685 0.008861187 0.128696264 5.58E-05 4.253529422 0.284447882 SFISPIPSK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 SFISPIPSKR 10 1 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 0 1 SFISPIPSK(1)R 92.239 0.0062935 2983600 1513.5 918.46 1653.9 949.61 1207.4 2137.6 1192 740.24 957.97 1220.1 FALSE TRUE FALSE 1393.704878 997.8475898 1715.194989 945.6807654 1193.002544 1694.237664 1225.444312 965.9357684 852.8830877 1262.498384 1.103926069 0.79037534 1.358572027 0.74905503 0.944953719 1.341972145 0.970650202 0.765098618 0.675551825 1 10.30206583 SFLDSGY(ph)R ddPTM_HeLa_Curcumin_4h_R1 3 SFLDSGYR 8 0 P18206;P18206-2 P18206 VCL Vinculin 1 0 SFLDSGY(1)R;SFLDSGY(1)R;SFLDSGY(1)R ;; 171.38 0.0056863 79035000 10558.2 5180.3 10523.1 8263.8 10932.8 13331.9 9258.1 11283.6 7931.2 8219.8 TRUE FALSE FALSE 9722.507329 5628.062049 10913.09534 8229.606585 10802.4335 10566.71366 9517.857369 14723.9177 7061.167203 8505.437438 1.143093157 0.661701657 1.28307279 0.967570057 1.270062073 1.242348055 1.119032083 1.731118217 0.830194479 1 13.05416972 -1 0.778521357 1.055350766 136.4377763 0.54382121 0.18735873 231.8252346 0.833022974 0.025980525 55274.74761 0.1 1 135.3824255 SFLNYYADLET(ph)SAR ddPTM_HeLa_Curcumin_4h_R1 1 SFLNYYADLETSAR 14 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 0 S(0.008)FLNYY(0.001)ADLET(0.755)S(0.236)AR 131.09 0.0030627 4026500 308.99 267.17 336.04 416.23 392.64 492.6 350.62 225.57 375.83 186.86 TRUE FALSE FALSE 284.5331155 290.2629843 348.493938 414.5077505 387.9580244 390.4292073 360.4574536 294.3452546 334.6023893 193.3533711 1.471570492 1.501204673 1.802368048 2.143783417 2.006471479 2.019252134 1.864241888 1.522317676 1.730522656 1 7.595096108 -7.652015171 0.619568593 1.066726057 1.928201458 0.290379979 0.272192998 0.232600646 0.203427896 0.069994492 0.061635662 2.23E-08 7.652015171 0.861475401 SFLSEPSS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 3 SFLSEPSSPGR 11 0 Q69YN4;H0YC41;Q69YN4-3 Q69YN4 KIAA1429 Protein virilizer homolog 1 0 SFLSEPS(0.002)S(0.998)PGR;SFLSEPS(0.001)S(0.999)PGR;SFLSEPS(0.133)S(0.867)PGR ;; 174.77 0.00021218 436060000 15344.8 12635 13776.9 15143.1 13862.6 16593.4 13011.1 11699.2 14938.9 14160.7 TRUE FALSE FALSE 14130.24289 13727.1131 14287.48403 15080.44186 13697.29755 13151.74179 13376.15645 15266.23222 13300.14005 14652.78327 0.96433849 0.936826325 0.975069635 1.029186168 0.93479152 0.897559293 0.91287479 1.041865695 0.907686942 1 13.83888711 -9.585442275 0.321856883 1.023158824 0.954006028 0 0.052664597 7.578717489 0.872181913 0.194934437 0.022050354 2.60E-10 9.585442275 -0.069152796 SFLVASVLPGPDGNINS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 2 SFLVASVLPGPDGNINSPTR 20 0 Q7Z3K3-5;Q7Z3K3-7;Q7Z3K3-2;Q7Z3K3-3;Q7Z3K3-6;Q7Z3K3 Q7Z3K3-5 POGZ Pogo transposable element with ZNF domain 1 0 SFLVASVLPGPDGNINS(0.963)PT(0.037)R;SFLVAS(0.001)VLPGPDGNINS(0.769)PT(0.231)R ; 183.6 8.57E-08 39516000 4029.2 3716 4156.1 3823.5 3478.6 4905.7 3376.8 4351.6 3754.6 3243.2 TRUE FALSE FALSE 3710.284568 4037.194482 4310.128722 3807.67937 3437.119967 3888.202521 3471.54392 5678.382808 3342.729774 3355.900959 1.10560014 1.203013597 1.284343244 1.134622093 1.024201849 1.158616589 1.034459587 1.692059115 0.996075216 1 11.71248442 -4.258409489 24.98548888 1.087056176 1.692059338 0.788336291 0.090922491 102.7728808 847455.9341 0.013866059 0.131192801 5.52E-05 4.258409489 0.605003162 SFLVIVDGS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SFLVIVDGSPK 11 0 Q9H116-4;Q9H116 Q9H116-4 GZF1 GDNF-inducible zinc finger protein 1 1 0 SFLVIVDGS(1)PK;SFLVIVDGS(1)PK ; 135.02 0.0020936 28892000 4472.3 3657.7 4024.3 4122.2 4335.4 4412.4 4100.6 2819.91 4252.8 3469.1 TRUE FALSE FALSE 4118.312736 3973.85529 4173.444098 4105.143429 4283.703187 3497.218502 4215.6518 3679.687578 3786.27848 3589.650967 1.147273864 1.107031109 1.162632283 1.143605177 1.193348107 0.974250292 1.174390446 1.025082275 1.054776221 1 11.80962786 -9.335374524 0.996000771 0.998162424 1.119745234 0.203896011 0.06664796 0.50273917 0.871345977 0.044308654 0.010973368 4.62E-10 9.335374524 0.12158281 SFPVNSDVGVLK ddPTM_HeLa_Curcumin_4h_R1 2 SFPVNSDVGVLK 12 0 B0YIW6;P48444;P48444-2 B0YIW6 ARCN1 Coatomer subunit delta 0 0 ; ; 147.37 6.96E-05 1616300 1534.65 1298.8 1319.55 1802.25 1402.3 776.75 925.33 1161.01 1366.1 1651.88 FALSE FALSE TRUE 1413.180833 1411.062485 1368.453684 1794.792767 1385.578488 615.6432942 951.2922694 1514.996604 1216.242248 1709.282707 0.826768344 0.825529024 0.80060114 1.050026868 0.810619848 0.360176401 0.556544722 0.886334717 0.711551251 1 10.73917532 -5.508652867 24.32634884 0.90794157 0.594708993 0.36688014 0.152853735 289.104149 494369.1085 0.020428285 0.044058226 3.10E-06 5.508652867 -0.313232577 SFS(ph)ASQSTDR ddPTM_HeLa_Curcumin_4h_R1 1 SFSASQSTDR 10 0 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 0 S(0.362)FS(0.522)AS(0.116)QSTDR 122.46 0.0041406 28780000 1246.2 1436.9 1823.8 1246.5 1738.6 1717.6 1801.8 1150.8 1245 1185.8 TRUE FALSE FALSE 1147.561955 1561.099233 1891.391632 1241.342313 1717.868331 1361.350399 1852.353659 1501.673622 1108.426615 1227.006462 0.935253392 1.272282813 1.541468355 1.011683599 1.400048316 1.109489185 1.509652733 1.223851438 0.903358417 1 10.26092713 -7.237157867 7.342144321 0.969360187 1.299691819 0.510001596 0.156395707 0.114316225 26.92600153 0.023466956 0.028422758 5.79E-08 7.237157867 0.330331631 SFS(ph)ASQSTDREGASPVTEVR ddPTM_HeLa_Curcumin_4h_R1 1 SFSASQSTDREGASPVTEVR 20 1 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 0 S(0.308)FS(0.452)AS(0.05)QS(0.148)T(0.042)DREGASPVTEVR 54.171 0.011098 41235000 854.86 634.17 813.13 738.68 757.29 894.03 670.82 767.18 973.8 725.7 TRUE FALSE FALSE 787.196929 688.984829 843.2653131 735.6235379 748.2598114 708.5981002 689.6414038 1001.08965 866.9765763 750.918021 1.048312741 0.917523364 1.122979193 0.979632287 0.996460053 0.943642422 0.918397727 1.333154382 1.15455556 1 9.552511605 -4.251567937 24.80220565 1.007762863 1.333154579 0.620997208 0.075952138 491.7372707 1235472.543 0.008090709 0.146256939 5.60E-05 4.251567937 0.325391716 SFS(ph)EDTLMDGPAR ddPTM_HeLa_Curcumin_4h_R1 2 SFSEDTLMDGPAR 13 0 Q9BRG2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 0 S(0.007)FS(0.993)EDTLMDGPAR;S(0.015)FS(0.98)EDT(0.005)LMDGPAR ; 116.9 0.0032564 15531200 5022 4222.7 4146 4298.9 4158.2 5592.7 4781.9 4312.4 4978.8 4486.5 TRUE FALSE FALSE 4624.503401 4587.691372 4299.654407 4281.112291 4108.616181 4432.710977 4916.067244 5627.230908 4432.638096 4642.405541 0.996143779 0.988214263 0.926169498 0.922175422 0.8850188 0.954830623 1.058948254 1.212136867 0.954814925 1 12.18065684 -4.370229134 2.654872066 0.9766905 1.232042018 0.785854324 0.040450987 0.158383823 1.664142119 0.006815778 0.078878398 4.26E-05 4.370229134 0.255351517 SFS(ph)EDVISHK ddPTM_HeLa_Curcumin_4h_R1 1 SFSEDVISHK 10 0 F6QMI7;Q03001;F8W9J4;Q03001-14;E9PHM6;A0A494C1D7;Q03001-8;Q03001-10;H0YC82 F6QMI7 DST Dystonin 1 0 S(0.245)FS(0.755)EDVISHK 92.112 0.008416 9408400 6678.3 5720.6 6232.7 5510 7001.4 7283.4 6007.4 4162.4 6887.2 5423.3 TRUE FALSE FALSE 6149.705508 6215.063174 6463.689345 5487.20108 6917.912878 5772.740739 6175.951476 5431.496599 6131.691391 5611.759271 1.095860533 1.107507089 1.151811586 0.977804074 1.232752964 1.028686453 1.100537492 0.96787769 1.092650467 1 12.45423741 -9.189807116 0.932273916 0.999973214 1.086211413 0 0.079668864 0.791936689 1.238021628 0.045534254 0.01285999 6.46E-10 9.189807116 0.086238199 SFS(ph)ENGDR ddPTM_HeLa_Curcumin_4h_R1 1 SFSENGDR 8 0 P47974 P47974 ZFP36L2 "Zinc finger protein 36, C3H1 type-like 2" 1 0 S(0.024)FS(0.976)ENGDR 96.015 0.017385 15206000 1565 1412.8 1601.9 1975.5 1978.1 2633.4 1923.4 1503.2 1793.5 1903.5 TRUE FALSE FALSE 1441.128599 1534.916137 1661.267823 1967.325904 1954.512449 2087.203155 1977.365427 1961.51876 1596.757537 1969.646483 0.731668658 0.77928509 0.843434513 0.99882183 0.99231637 1.059684148 1.003918949 0.995873512 0.810682298 1 10.943721 -6.229191677 6.193045581 0.859450471 1.012297255 0.608241389 0.069475815 0.182334551 22.65140351 0.016192113 0.026670073 5.90E-07 6.229191677 0.152846784 SFS(ph)LEGLTGGAGVGNKPSSSLEVSSANAEELR ddPTM_HeLa_Curcumin_4h_R1 1 SFSLEGLTGGAGVGNKPSSSLEVSSANAEELR 32 1 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2;A0A087WY36;H0YLH1;H0YMW2 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 S(0.124)FS(0.864)LEGLT(0.005)GGAGVGNKPS(0.001)S(0.001)S(0.003)LEVS(0.001)SANAEELR 56.123 0.00067361 19155000 690.58 507.51 479.89 422.08 662.18 759.92 327.72 325.53 762.58 474.56 TRUE FALSE FALSE 635.9198643 551.376903 497.6751456 420.3335448 654.283936 602.3040259 336.9149412 424.7825984 678.9268819 491.0509247 1.295018159 1.122850758 1.013489886 0.855987686 1.332415648 1.22656123 0.686109982 0.865047956 1.382599742 1 8.939728837 -4.760760072 24.99996551 1.130160478 0.775578903 0.460346683 0.162139251 11.9094677 438196.1462 0.022462579 0.07514793 1.73E-05 4.760760072 -0.354581576 SFS(ph)PEER ddPTM_HeLa_Curcumin_4h_R1 1 SFSPEER 7 0 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;A0A3B3IRI3;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISZ5;Q9UDY2-5;A0A3B3IRV6;A0A3B3ISF1;A0A3B3IT83 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 SFS(1)PEER 106.68 0.016941 52704000 4444.7 3731.7 3846.2 4223.4 3643.7 4222.5 3195.9 3953.4 4546.8 3546.4 TRUE FALSE FALSE 4092.897305 4054.25152 3988.743555 4205.92469 3600.251257 3346.705903 3285.568353 5158.773461 4048.027416 3669.637136 1.11534115 1.104809923 1.086958576 1.146141848 0.981091897 0.911999137 0.895338757 1.405799339 1.103113814 1 11.8414217 -4.246012379 24.79089526 1.044769376 1.405799635 0.633623258 0.083703167 1419.647793 2281306.521 0.012538239 0.400637083 5.68E-05 4.246012379 0.361030259 SFS(ph)SPENFQR ddPTM_HeLa_Curcumin_4h_R1 1 SFSSPENFQR 10 0 G3V1T9;J3KPD3;Q9Y580;I3L521;F5GXV8;F5GY08 G3V1T9 RBM7 RNA-binding protein 7 1 0 S(0.065)FS(0.812)S(0.123)PENFQR 166.29 0.000553 12928000 2701.5 1917.3 1871.1 2306.5 2134.9 3366.2 3211.8 656.1 2567 1609.8 TRUE FALSE FALSE 2487.673424 2083.022869 1940.444612 2296.956314 2109.442712 2668.012175 3301.914464 856.1418697 2285.406522 1665.74043 1.493434018 1.250508681 1.164914159 1.378940123 1.266369402 1.601697435 1.982250298 0.513970757 1.372006395 1 10.70194789 -9.445846638 1.084709339 0.992314596 1.366493453 0 0.370009788 0.853518827 1.735858328 0.251120678 0.057515079 3.58E-10 9.445846638 0.374178857 QQSTS(ph)S(ph)DRVSQTPESLDFLKVPDQGAAGVR ddPTM_HeLa_Curcumin_4h_R1 1 QQSTSSDRVSQTPESLDFLKVPDQGAAGVR 30 2 Q12965 Q12965 MYO1E Unconventional myosin-Ie 2 0 QQS(0.328)T(0.328)S(0.518)S(0.518)DRVS(0.219)QT(0.083)PES(0.008)LDFLKVPDQGAAGVR 54.419 0.0024062 5601200 653.77 565.94 747.27 752.91 685.91 1110 1592 3550.8 531.13 503.81 TRUE FALSE FALSE 602.0234146 614.8573318 774.9644836 749.7946579 677.7309712 879.7734877 1636.667235 4633.422574 472.8663678 521.31736 1.154811754 1.179429996 1.486550311 1.438269115 1.300035301 1.68759676 3.139483472 8.887911529 0.907060467 1 9.026018093 -4.054202729 1.508817443 1.153783631 15.37623937 0.992587997 0.198228847 0.114148773 0.160296681 0.031412721 2.790813185 8.83E-05 4.054202729 14.22245574 up SFSASQSTDREGAS(ph)PVTEVR ddPTM_HeLa_Curcumin_4h_R1 2 SFSASQSTDREGASPVTEVR 20 1 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 0 S(0.004)FS(0.001)AS(0.002)QS(0.003)T(0.002)DREGAS(0.973)PVT(0.015)EVR;SFSASQSTDREGAS(0.982)PVT(0.018)EVR ; 68.952 0.0030387 49317000 1294.8 831.46 886.82 1022.79 1058.16 1126.33 630.16 460.41 1234.06 1068.49 TRUE FALSE FALSE 1192.315214 903.3276975 919.6863293 1018.557966 1045.542133 892.7164616 647.8405936 600.7868895 1098.686705 1105.619948 1.078413261 0.817032742 0.831828632 0.921255055 0.945661423 0.807435198 0.585952338 0.543393678 0.993729091 1 10.11063984 -3.932858526 0.414691861 1.03018647 4.48E-13 0.759754409 0.08149675 2.290167274 0.219315335 0.023373449 1.232491394 0.000116719 3.932858526 -1.03018647 SFSEDAVT(ph)DSSGSGTLPR ddPTM_HeLa_Curcumin_4h_R1 1 SFSEDAVTDSSGSGTLPR 18 0 Q27J81-2;A0A0A0MQU1;Q27J81 Q27J81-2 INF2 Inverted formin-2 1 0 S(0.001)FS(0.001)EDAVT(0.383)DS(0.046)S(0.207)GS(0.28)GT(0.083)LPR 102.39 0.0034938 4591100 1194.1 1162.9 1318.3 1305.6 1113.9 1638.3 1845 1599.9 1247.8 1050.8 TRUE FALSE FALSE 1099.585725 1263.415894 1367.157358 1300.197773 1100.61747 1298.498113 1896.765734 2087.702145 1110.919462 1087.315222 1.011285139 1.161959171 1.257369832 1.195787337 1.012234031 1.194224165 1.744448801 1.920052348 1.021708737 1 10.08655454 -4.750715615 2.637298886 1.051824225 1.906083715 0.911052469 0.091215024 0.061784767 0.836221511 0.015613099 0.073755834 1.78E-05 4.750715615 0.854259491 SFSEDAVTDSS(ph)GSGTLPR ddPTM_HeLa_Curcumin_4h_R1 1 SFSEDAVTDSSGSGTLPR 18 0 Q27J81-2;A0A0A0MQU1;Q27J81 Q27J81-2 INF2 Inverted formin-2 1 0 SFSEDAVTDS(0.231)S(0.539)GS(0.113)GT(0.117)LPR 175.19 2.66E-06 13641000 1939.1 1531.2 2162.6 2066.4 2182.8 2148.5 2346.2 1719.5 2176.1 2179.8 TRUE FALSE FALSE 1785.618189 1663.550105 2242.747858 2057.849784 2156.771536 1702.876881 2412.028058 2243.767634 1937.387274 2255.547888 0.791656075 0.737537037 0.994325091 0.912350297 0.95620738 0.754972612 1.069375681 0.99477721 0.858943091 1 11.1392622 SFSEDAVTDSSGSGT(ph)LPR ddPTM_HeLa_Curcumin_4h_R1 2 SFSEDAVTDSSGSGTLPR 18 0 Q27J81-2;A0A0A0MQU1;Q27J81 Q27J81-2 INF2 Inverted formin-2 1 0 SFSEDAVT(0.003)DS(0.059)S(0.234)GS(0.305)GT(0.399)LPR;SFSEDAVT(0.001)DS(0.105)S(0.308)GS(0.24)GT(0.346)LPR ; 271.45 1.21E-53 15390200 1868.84 1879.62 2217.59 2350.01 2339.13 2336.7 3522 1773.85 2063.35 1969.92 TRUE FALSE FALSE 1720.919342 2042.085977 2299.775836 2340.286281 2311.237402 1852.04208 3620.817841 2314.688699 1837.005667 2038.374573 0.844260601 1.001820766 1.128240053 1.148113949 1.133862948 0.908587707 1.776326043 1.135556109 0.901211039 1 10.99320347 -5.255959922 0.594355361 0.931650166 1.468070427 0.328283595 0.204746439 1.104104612 0.505816488 0.039189428 0.327675381 5.55E-06 5.255959922 0.536420261 SFSEDT(ph)LMDGPAR ddPTM_HeLa_Curcumin_4h_R1 1 SFSEDTLMDGPAR 13 0 Q9BRG2;M0QZQ6 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 0 S(0.022)FS(0.025)EDT(0.953)LMDGPAR 198.74 4.49E-06 23849000 3078.1 2086.7 1885.9 2090.4 2044.9 2674.3 2403.4 2744.3 2340.2 2183.7 TRUE FALSE FALSE 2834.465137 2267.06505 1955.793113 2081.750479 2020.515903 2119.620034 2470.832936 3581.024437 2083.485915 2259.583412 1.254419342 1.003311069 0.865554731 0.921298354 0.894198414 0.938057884 1.093490473 1.584816217 0.922066388 1 11.1418411 -4.26573555 4.82323991 1.05471269 1.612256371 0.643508513 0.124970332 0.10975897 7.350949607 0.021743258 0.203598276 5.42E-05 4.26573555 0.557543681 SFSKEELMS(ph)SDLEETAGSTSIPK ddPTM_HeLa_Curcumin_4h_R1 3 SFSKEELMSSDLEETAGSTSIPK 23 1 O00567 O00567 NOP56 Nucleolar protein 56 1 0 SFSKEELMS(0.499)S(0.499)DLEET(0.002)AGSTSIPK;SFSKEELMS(0.499)S(0.499)DLEET(0.001)AGSTSIPK;SFSKEELMS(0.836)S(0.164)DLEETAGSTSIPK ;; 95.624 5.16E-05 894146000 10777 8928.5 8702 9369.5 8815.6 12399.5 8877.4 8028.4 11111.9 9748.4 TRUE FALSE FALSE 9923.989078 9700.239755 9024.503775 9330.731492 8710.479728 9827.703929 9126.475952 10476.2222 9892.952371 10087.15617 0.983824272 0.961642666 0.894652925 0.925011106 0.863521847 0.97427895 0.904762035 1.038570438 0.980747418 1 13.30023188 -7.102113059 3.084167549 0.992546719 0.930332697 0.22098163 0.045262972 0.23604869 4.300642942 0.007181492 0.008987711 7.90E-08 7.102113059 -0.062214022 SFSKEELMSS(ph)DLEETAGSTSIPK ddPTM_HeLa_Curcumin_4h_R1 2 SFSKEELMSSDLEETAGSTSIPK 23 1 O00567 O00567 NOP56 Nucleolar protein 56 1 0 SFSKEELMS(0.222)S(0.754)DLEET(0.02)AGS(0.002)T(0.001)SIPK;SFSKEELMS(0.095)S(0.904)DLEET(0.001)AGSTSIPK ; 128.55 2.98E-06 879170000 11686.9 8515.9 10598.5 12027 10210.1 11857 10469.7 8138.2 12656.3 9689.9 TRUE FALSE FALSE 10761.86953 9251.97645 10991.28973 11977.23546 10088.35123 9397.724544 10763.4516 10619.49972 11267.93555 10026.6233 1.073329396 0.922741004 1.096210499 1.194543277 1.006156402 0.937277113 1.073487183 1.059130217 1.123801624 1 13.29154821 SFSKEELMSS(ph)DLEETAGSTSIPKR ddPTM_HeLa_Curcumin_4h_R1 1 SFSKEELMSSDLEETAGSTSIPKR 24 2 O00567 O00567 NOP56 Nucleolar protein 56 1 0 S(0.001)FS(0.001)KEELMS(0.212)S(0.778)DLEET(0.008)AGSTSIPKR 62.823 0.0011233 61659000 1466.8 1095.8 1071.1 1305.5 1098.9 1478.2 944.86 1241.8 1788.3 1595.1 TRUE FALSE FALSE 1350.701232 1190.516069 1110.795908 1300.098187 1085.796335 1171.604657 971.3702286 1620.419103 1592.127964 1650.529606 0.818344141 0.721293374 0.672993628 0.787685469 0.657847233 0.70983559 0.58852033 0.981757066 0.964616423 1 10.6887133 -8.257966485 0.648148272 0.989718846 0.718139052 0.481488621 0.100570192 0.368031404 0.338082562 0.044674136 0.024214887 5.52E-09 8.257966485 -0.271579794 GGPAS(ph)PGGLQGLETR ddPTM_HeLa_Curcumin_4h_R1 4 GGPASPGGLQGLETR 15 0 C9JWC4;Q8NCD3-3;Q8NCD3-2;Q8NCD3 C9JWC4 HJURP Holliday junction recognition protein 1 0 GGPAS(1)PGGLQGLETR;GGPAS(0.971)PGGLQGLET(0.029)R;GGPAS(1)PGGLQGLETR;GGPAS(1)PGGLQGLETR ;;; 187.08 1.25E-05 254704000 13175 10560.7 10584.5 11390.2 11231.9 14262.5 10342.2 3253.4 13140.8 11197.3 TRUE FALSE FALSE 12132.18485 11473.51985 10976.77088 11343.07037 11097.96693 11304.29673 10632.3743 4245.346683 11699.28712 11586.40534 1.047105162 0.990257074 0.947383641 0.978998234 0.957843835 0.975651757 0.917659445 0.366407575 1.009742605 1 13.50014542 -4.213205532 2.557485103 1.004975857 0.181801553 0.973164048 0.030680905 0.083038284 0.612164549 0.00555344 0.154431102 6.12E-05 4.213205532 -0.823174304 down SFSQPEAGGS(ph)HHK ddPTM_HeLa_Curcumin_4h_R1 1 SFSQPEAGGSHHK 13 0 B7WPG3;V9GYK2;Q8WVV9-2;Q8WVV9-5;Q8WVV9;C9IYN3;Q8WVV9-3;Q8WVV9-4 B7WPG3 HNRNPLL Heterogeneous nuclear ribonucleoprotein L-like 1 0 SFSQPEAGGS(1)HHK 79.92 0.01048 9145100 5126.1 5979.3 4395.6 4454.5 5915.2 8879.6 7980.8 4111.5 5571.5 4760.2 TRUE FALSE FALSE 4720.363776 6496.124049 4558.504803 4436.068459 5844.665103 7037.870866 8204.719769 5365.077423 4960.320389 4925.616596 0.958329518 1.318844844 0.925468866 0.900611806 1.186585474 1.428830428 1.665724404 1.089219455 1.007045573 1 12.26608862 -5.466178724 3.420080164 0.998941674 1.418715251 0.488889039 0.17061063 0.131634796 3.047623741 0.023284756 0.053974092 3.42E-06 5.466178724 0.419773577 SFSSAPPLILTCSADK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 SFSSAPPLILTCSADKK 17 1 P42568-2;P42568 P42568-2 MLLT3 Protein AF-9 0 1 SFSSAPPLILTCSADK(1)K 129.54 5.50E-11 0 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 SFT(ph)PDHVVYAR ddPTM_HeLa_Curcumin_4h_R1 3 SFTPDHVVYAR 11 0 Q6NZI2;Q6NZI2-3;Q6NZI2-2 Q6NZI2 PTRF Polymerase I and transcript release factor 1 0 S(0.147)FT(0.853)PDHVVYAR;S(0.131)FT(0.869)PDHVVYAR;S(0.021)FT(0.979)PDHVVYAR ;; 120.87 0.0038817 62079000 8851.8 7832.2 7689.8 7455 8233.8 12400.8 11745 5119.38 10984.8 6971.6 TRUE FALSE FALSE 8151.17069 8509.180468 7974.790753 7424.153185 8135.617313 9828.734294 12074.53309 6680.255395 9779.794923 7213.862581 1.129931517 1.179559546 1.105481379 1.029150902 1.127775477 1.362478725 1.673795828 0.926030309 1.355694652 1 12.81655623 -5.324689282 4.377883446 1.074851169 1.356696876 0.112875627 0.197037622 0.174974284 6.749704135 0.023342104 0.055073754 4.73E-06 5.324689282 0.281845707 SFTGGLGQLVVPS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SFTGGLGQLVVPSK 14 0 Q9Y3Q8 Q9Y3Q8 TSC22D4 TSC22 domain family protein 4 1 0 S(0.08)FT(0.001)GGLGQLVVPS(0.918)K 142.98 0.00069181 137900000 8064 5200.2 8027.1 8272.2 8515.7 8205.7 6172.2 7351.1 6020.7 5992.5 TRUE FALSE FALSE 7425.725891 5649.682116 8324.591387 8237.971828 8414.155839 6503.745323 6345.37532 9592.41655 5360.244273 6200.738929 1.197554997 0.911130461 1.342516026 1.328546795 1.356960184 1.048866175 1.02332567 1.546979587 0.864452501 1 12.59822443 -13.52287874 0.129400794 0.234424122 1.318412568 0.310743203 0.177586568 100.3778181 0.922224383 19.77311611 0.639608218 3.00E-14 13.52287874 1.083988446 SFTSS(ph)SPSS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 SFTSSSPSSPSR 12 0 O94875-12;O94875-11;O94875-9;O94875-5;O94875-3;O94875-8;H7BXR3;O94875-4;H7BZX1;H7C1R7;H7BZK1;O94875;O94875-7;O94875-2;O94875-10 O94875-12;O94875-10 SORBS2 Sorbin and SH3 domain-containing protein 2 2 0 S(0.006)FT(0.026)S(0.329)S(0.504)S(0.134)PS(0.001)S(0.986)PS(0.013)R 112.84 0.011299 76995000 6680.5 5581.4 6407.2 6677.6 6385 7336 5779.6 2730 6597 6119 TRUE FALSE FALSE 6151.731376 6063.831346 6644.656468 6649.969861 6308.863045 5814.430906 5941.760021 3562.364433 5873.325605 6331.634795 0.971586577 0.957703902 1.049437734 1.050276915 0.996403496 0.918314321 0.938424311 0.562629486 0.927615978 1 12.62836233 -3.924959671 1.567555202 0.992135358 1.84E-19 0.897717029 0.042330606 0.530049127 0.608182304 0.005510129 1.040515021 0.000118861 3.924959671 -0.992135358 SFTSSS(ph)PSS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 SFTSSSPSSPSR 12 0 O94875-12;O94875-11;O94875-9;O94875-5;O94875-3;O94875-8;H7BXR3;O94875-4;H7BZX1;H7C1R7;H7BZK1;O94875;O94875-7;O94875-2;O94875-10 O94875-12;O94875-10 SORBS2 Sorbin and SH3 domain-containing protein 2 2 0 SFT(0.002)S(0.012)S(0.392)S(0.595)PS(0.313)S(0.684)PS(0.003)R 104.94 0.016911 4894700 1978 1928.9 2372.4 2344.3 1727.7 2278.8 1636.9 1095.2 2153.3 1742.9 TRUE FALSE FALSE 1821.439213 2095.625521 2460.323231 2334.599908 1707.098306 1806.151193 1682.827009 1429.121438 1917.088377 1803.465645 1.009966127 1.161999136 1.364219628 1.294507558 0.94656547 1.001489104 0.933107328 0.792430642 1.063002438 1 10.81655623 -4.48097656 1.360161871 1.062169205 0.746709344 0.347893195 0.132183433 1.030621852 2.212973538 0.022831186 0.397271801 3.30E-05 4.48097656 -0.315459861 SFVLNLGK ddPTM_HeLa_Curcumin_4h_R1 2 SFVLNLGK 8 0 P09382 P09382 LGALS1 Galectin-1 0 0 ; ; 130.27 0.0016363 11816000 7779.5 2949.3 6292.3 3780 5665.1 13597.8 8796.3 8416.9 4604.5 6518.9 FALSE FALSE TRUE 7163.744366 3204.22435 6525.498173 3764.359362 5597.547382 10777.463 9043.100504 10983.17406 4099.39787 6745.43129 1.062014282 0.47502142 0.967395248 0.558060589 0.829827945 1.597742611 1.34062599 1.628238965 0.607729542 1 12.71969497 -5.260753493 24.9999494 0.934762495 1.504044892 0.643792136 0.233163263 33.90514783 1235781.18 0.032344435 0.077414104 5.49E-06 5.260753493 0.569282397 SGAAAEK(ac)ADSR ddPTM_HeLa_Curcumin_4h_R1 1 SGAAAEKADSR 11 1 Q9H967 Q9H967 WDR76 WD repeat-containing protein 76 0 1 SGAAAEK(1)ADSR 91.313 0.019265 706770 384.65 342 375.86 372.41 238.49 280.97 147.5 122.78 201.07 296.83 FALSE TRUE FALSE 354.2045466 371.5609561 389.7897022 370.8690661 235.6461625 222.6936548 151.638453 160.2150568 179.0131241 307.1448204 1.153216734 1.209725613 1.26907464 1.207472962 0.76721516 0.725044474 0.493703435 0.521627083 0.582829702 1 8.262775244 -5.422251324 1.934926545 1.109388287 0.540251587 0.559811909 0.194271658 0.106865692 0.776306344 0.017849333 0.049945693 3.78E-06 5.422251324 -0.5691367 SGAHS(ph)SASPPR ddPTM_HeLa_Curcumin_4h_R1 1 SGAHSSASPPR 11 0 P18615;P18615-3;A0A0A0MT02;P18615-4;A0A0G2JI50;E9PD43;A0A0A0MSN9 P18615 NELFE Negative elongation factor E 1 0 SGAHS(0.866)S(0.067)AS(0.067)PPR 89.663 0.0084182 10659000 144.5 193.03 64.504 0 0 203.96 0 117.46 135.02 188.07 TRUE FALSE FALSE 133.0626725 209.7146531 66.89457498 0 0 161.6563969 0 153.2730133 120.2086438 194.6054185 0.683756257 1.077640359 0.343744668 0 0 0.830688057 0 0.787609176 0.617704506 1 7.60440807 -6.713091755 9.205642772 0.863392411 0.304297471 0.402894298 0.307748858 0.224908729 40.33634234 0.045669245 0.064504738 1.94E-07 6.713091755 -0.559094939 DVSYQGGK(ac)SIK ddPTM_HeLa_Curcumin_4h_R1 2 DVSYQGGKSIK 11 1 Q8NEZ4;Q8NEZ4-3;H0YMU7 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 0 1 ; DVSYQGGK(1)SIK;DVSYQGGK(1)SIK 193.28 3.11E-16 15573400 4159.4 3280.7 3826.2 4124.7 3406.7 3977.7 2808.7 936.4 3915.5 3451 FALSE TRUE FALSE 3830.179101 3564.269089 3968.002338 4107.633084 3366.077327 3152.680182 2887.504563 1221.904049 3485.979446 3570.921993 1.072602288 0.998136923 1.111198269 1.150300424 0.942635357 0.88287568 0.808615973 0.34218167 0.976212713 1 11.8020809 -4.20069973 1.160400454 1.041515863 4.60E-18 0.910714526 0.065191961 0.358652678 0.357356361 0.009645028 0.466418774 6.30E-05 4.20069973 -1.041515863 down SGAMS(ph)PMSWNSDASTSEAS ddPTM_HeLa_Curcumin_4h_R1 2 SGAMSPMSWNSDASTSEAS 19 0 Q13158 Q13158 FADD FAS-associated death domain protein 1 0 S(0.143)GAMS(0.763)PMS(0.095)WNSDASTSEAS;S(0.007)GAMS(0.992)PMS(0.001)WNSDASTSEAS ; 133.52 0.00020568 11703000 5161.1 4207.8 4376.8 4614.3 3892.7 3559 2498.3 1840.49 4854.3 4230 TRUE FALSE FALSE 4752.593489 4571.503482 4539.008058 4595.207249 3846.282095 2820.823282 2568.395574 2401.646928 4321.795435 4376.992185 1.085812651 1.044439489 1.037015344 1.049855027 0.878750048 0.644466145 0.586794645 0.548698016 0.987389342 1 12.09572409 -5.351887727 1.875891827 1.043189478 0.564768971 0.978743376 0.029146349 0.037811316 0.255393713 0.005066702 0.015218908 4.45E-06 5.351887727 -0.478420506 SGAMVK(ac)MAAAGGGGGGGR ddPTM_HeLa_Curcumin_4h_R1 2 SGAMVKMAAAGGGGGGGR 18 1 P14866 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 1 ; SGAMVK(1)MAAAGGGGGGGR;SGAMVK(1)MAAAGGGGGGGR 128.85 0.00019463 7053000 2666 2463.7 3017.7 2687.4 2269.96 1964.69 1463.5 1444.14 2799.1 2393.2 FALSE TRUE FALSE 2454.983287 2676.65125 3129.538617 2676.280251 2242.89221 1557.191147 1504.561871 1884.451638 2492.045733 2476.363522 0.991366278 1.080879776 1.263763817 1.08072996 0.905720097 0.628821711 0.607569066 0.760975366 1.006332758 1 11.2740074 -5.419290375 3.490995682 1.029900592 0.660642418 0.802091325 0.088431185 0.093921434 2.114617301 0.014436308 0.034069238 3.81E-06 5.419290375 -0.369258174 SGAQAS(ph)STPLSPTR ddPTM_HeLa_Curcumin_4h_R1 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 SGAQAS(0.47)S(0.281)T(0.246)PLS(0.001)PT(0.001)R 95.197 0.0089094 0 801.38 1031.2 575.63 626.05 615.52 826.46 582.12 648.52 696.53 673.67 TRUE FALSE FALSE 737.9499274 1120.332333 596.9633542 623.459571 608.180326 655.0428799 598.4527205 846.2507626 620.1224016 697.0799824 1.058630209 1.607179035 0.856377129 0.894387426 0.872468499 0.939695439 0.858513708 1.21399378 0.889600071 1 9.445180389 SGAQASS(ph)TPLSPTR ddPTM_HeLa_Curcumin_4h_R1 3 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 S(0.017)GAQAS(0.162)S(0.539)T(0.23)PLS(0.049)PT(0.003)R;S(0.212)GAQAS(0.066)S(0.258)T(0.138)PLS(0.066)PT(0.258)R;SGAQAS(0.062)S(0.67)T(0.204)PLS(0.062)PT(0.001)R ;; 154.81 0.00040576 242811000 10555.1 10132.8 9229.6 10829 10468.6 11672.7 8679.1 13727.9 11541.6 9749.5 TRUE FALSE FALSE 9719.652697 11008.63408 9571.657095 10784.19247 10343.76878 9251.650442 8922.612187 17913.47351 10275.51536 10088.2944 0.963458471 1.091228472 0.948788439 1.068980745 1.025323843 0.917067849 0.884452003 1.775669187 1.018558237 1 13.30039466 -4.256911882 24.99972666 0.986686095 1.775669503 0.936362589 0.061369201 75.07739822 414544.0343 0.008093346 0.086249341 5.53E-05 4.256911882 0.788983408 SGAQASST(ph)PLS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 2 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 SGAQAS(0.044)S(0.398)T(0.558)PLS(0.789)PT(0.211)R;SGAQAS(0.031)S(0.157)T(0.811)PLS(0.976)PT(0.024)R ; 161.94 0.0011773 988490000 12598.8 11329.9 10178 11732.8 12566 22717.5 21638.1 8467.7 13259.9 9027.6 TRUE FALSE FALSE 11601.59169 12309.20607 10555.20563 11684.25278 12416.15866 18005.63442 22245.20685 11049.46275 11805.32214 9341.308428 1.241966452 1.317717552 1.129949376 1.250815437 1.329166974 1.927528093 2.381380191 1.182860285 1.26377608 1 13.18940893 -5.388604209 3.259374696 1.146510757 1.886398247 0.480396873 0.288242265 0.132293547 2.622174592 0.039290439 0.095122786 4.09E-06 5.388604209 0.73988749 SGAQASST(ph)PLSPT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 2 0 SGAQAS(0.058)S(0.276)T(0.666)PLS(0.209)PT(0.791)R 106.82 0.012477 464120000 4181.5 3548 3865.7 4103.6 4225 7115 7516.6 3159.7 4480.9 3437 TRUE FALSE FALSE 3850.529863 3854.67331 4008.966243 4086.620391 4174.619634 5639.268797 7727.495566 4123.077985 3989.356481 3556.435494 1.082693576 1.083858632 1.127242783 1.149077608 1.173821272 1.585651928 2.172820392 1.159328769 1.121728902 1 11.79621628 -5.27782405 3.140266666 1.061195377 1.709993777 0.522396735 0.232892312 0.117272032 2.361546169 0.029861479 0.078369709 5.27E-06 5.27782405 0.648798401 SGAQASST(ph)PLSPTR ddPTM_HeLa_Curcumin_4h_R1 1 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 S(0.289)GAQAS(0.019)S(0.131)T(0.426)PLS(0.131)PT(0.003)R 132.15 0.0029615 6645000 3147.2 2565.5 2821.4 2584.5 2589.9 2761.3 2233.6 4545.1 3096.7 2683.9 TRUE FALSE FALSE 2898.095799 2787.250388 2925.963566 2573.806024 2559.017134 2188.575254 2296.268805 5930.880067 2756.999758 2777.165325 1.043544571 1.003631423 1.05357918 0.926774507 0.921449332 0.788060845 0.826839074 2.135587685 0.992738795 1 11.43939735 -4.256665598 24.98216141 0.983971673 2.135588158 0.940456135 0.089088022 94.08033902 492324.4578 0.013953394 0.15207162 5.54E-05 4.256665598 1.151616485 SGAQASSTPLS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 8 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 SGAQASSTPLS(0.77)PT(0.23)R;SGAQASSTPLS(0.891)PT(0.109)R;SGAQASSTPLS(0.674)PT(0.325)R;S(0.005)GAQAS(0.077)S(0.275)T(0.275)PLS(0.347)PT(0.022)R;SGAQASSTPLS(0.711)PT(0.289)R;SGAQASSTPLS(0.978)PT(0.022)R;SGAQASSTPLS(0.88)PT(0.12)R;SGAQASSTPLS(0.5)PT(0.5)R ;;;;;;; 169.15 0.00020588 12097548500 17472.43 14010.23 14067.49 16642.36 15856.83 17349.38 11085.22 11120.35 17091.75 15604.33 TRUE FALSE FALSE 16089.46873 15221.21185 14588.84355 16573.49832 15667.74766 13750.92302 11396.24144 14510.89352 15216.82779 16146.57931 0.996462992 0.942689567 0.90352534 1.026440214 0.9703447 0.851630724 0.705799118 0.89869769 0.94241805 1 13.97894094 -5.194142534 3.437281776 0.987794137 0.798336489 0.589203904 0.056701885 0.097183211 2.259569145 0.00735587 0.020208855 6.40E-06 5.194142534 -0.189457649 SGAQASSTPLSPT(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 1 0 SGAQASSTPLS(0.272)PT(0.728)R;SGAQASSTPLS(0.269)PT(0.731)R ; 133.23 0.0028594 515220000 4388.99 3481.47 3776.6 3776.07 3696.65 4485 2452.96 2070.98 4742.2 3250.83 TRUE FALSE FALSE 4041.59681 3782.392754 3916.564118 3760.445623 3652.569863 3554.760444 2521.783456 2702.412268 4221.992524 3363.796101 1.20149875 1.124441744 1.164328634 1.117917231 1.085847582 1.056770487 0.749683804 0.803381712 1.255127362 1 11.71587454 -4.815915752 4.72127236 1.104627218 0.774370573 0.794838739 0.07057083 0.069195172 3.155869405 0.010967731 0.03643322 1.53E-05 4.815915752 -0.330256645 SGAQASSTPLSPTR ddPTM_HeLa_Curcumin_4h_R1 2 SGAQASSTPLSPTR 14 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 184.21 4.25E-08 16479100 2387.9 1882.22 1906.91 2085.1 2061.97 2441.2 1770.56 1937.29 2338.5 1752.76 FALSE FALSE TRUE 2198.895195 2044.91071 1977.581762 2076.472409 2037.382354 1934.867602 1820.237148 2527.960803 2081.972401 1813.66828 1.21240208 1.127499848 1.090376771 1.144901982 1.123348948 1.066825518 1.003621869 1.393838571 1.147934506 1 10.8246949 -9.52051 1.271720197 0.999902715 1.143873065 0 0.107822468 0.527353361 1.525277072 0.065605711 0.01571107 3.02E-10 9.52051 0.143970349 SGAVQGAGSLGPGS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 1 SGAVQGAGSLGPGSPVR 17 0 Q9P270 Q9P270 SLAIN2 SLAIN motif-containing protein 2 1 0 SGAVQGAGSLGPGS(1)PVR 171.52 5.44E-05 154540000 3455.5 2741 2734.4 2605.5 2402 3832.2 3009.3 1327.3 3412.3 2353.4 TRUE FALSE FALSE 3181.993529 2977.919826 2835.739269 2594.719131 2373.357719 3037.358522 3093.732859 1731.98766 3037.979227 2435.180475 1.306676676 1.222874385 1.16448834 1.0655141 0.974612659 1.247282718 1.270432681 0.711235852 1.247537609 1 11.24981298 -6.261033605 21.91896216 1.156935065 1.072197886 0.125327951 0.164157823 18.12568723 978951.4715 0.027272335 0.043456169 5.48E-07 6.261033605 -0.084737179 TLST(ph)SDDVEDRENEK ddPTM_HeLa_Curcumin_4h_R1 1 TLSTSDDVEDRENEK 15 1 Q96A65;Q96A65-2 Q96A65 EXOC4 Exocyst complex component 4 1 0 T(0.051)LS(0.201)T(0.597)S(0.151)DDVEDRENEK 98.077 0.0037834 8242600 1067.9 805.28 1233.4 1431 1254 1896.8 2566.1 6442.5 1140.6 885.49 TRUE FALSE FALSE 983.3745882 874.8848149 1279.110889 1425.078901 1239.046869 1503.382299 2638.09786 8406.788592 1015.479034 916.2607116 1.073247577 0.95484266 1.396011935 1.555320318 1.352286367 1.640780053 2.879200021 9.175105389 1.108286125 1 9.839614349 -4.050934442 1.606631982 1.118883399 15.94116919 0.99055181 0.231366351 0.127624388 0.203683 0.037549385 3.450575506 8.89E-05 4.050934442 14.82228579 up SGDAAIVDMVPGKPMCVES(ph)FSDYPPLGR ddPTM_HeLa_Curcumin_4h_R1 2 SGDAAIVDMVPGKPMCVESFSDYPPLGR 28 1 Q5VTE0;P68104;A0A087WVQ9 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1 1 0 SGDAAIVDMVPGKPMCVES(0.669)FS(0.202)DY(0.128)PPLGR;SGDAAIVDMVPGKPMCVES(0.493)FS(0.493)DY(0.014)PPLGR ; 66.01 0.00019722 29543000 1279.34 1190.6 1300.1 1260.38 1029.37 1643.63 975.93 673.7 1581.86 1074.11 TRUE FALSE FALSE 1178.078889 1293.510159 1348.28285 1255.164882 1017.095435 1302.72261 1003.311969 879.1080287 1408.333916 1111.435243 1.05996179 1.163819635 1.213100681 1.12931895 0.915118935 1.172108424 0.902717433 0.790966486 1.267130879 1 10.11820818 -4.563742332 5.65910586 1.058461305 0.815479928 0.439068739 0.110119597 0.103457929 8.150733664 0.013012042 0.052798621 2.73E-05 4.563742332 -0.242981377 SGDAAIVDMVPGKPMCVESFSDYPPLGR ddPTM_HeLa_Curcumin_4h_R1 4 SGDAAIVDMVPGKPMCVESFSDYPPLGR 28 1 Q5VTE0;P68104;A0A087WVQ9 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1 0 0 ;;; ;;; 101.42 2.31E-07 134817000 7530.24 6109.27 6666.76 7449.25 6820.77 9153.69 6620.96 6774.2 7435.85 7230.4 FALSE FALSE TRUE 6934.213558 6637.328076 6913.83599 7418.426977 6739.436773 7255.111511 6806.726318 8839.622395 6620.155859 7481.655862 0.926828724 0.887146936 0.924105053 0.991548811 0.90079481 0.969720025 0.909788748 1.181506148 0.884851693 1 12.86914189 -4.254943467 24.70417863 0.951759096 1.18150627 0.737866325 0.043161876 258.7944533 984172.8373 0.005975205 0.075400236 5.56E-05 4.254943467 0.229747174 RGS(ph)GDTSSLIDPDTSLSELRDIYDLK ddPTM_HeLa_Curcumin_4h_R1 1 RGSGDTSSLIDPDTSLSELRDIYDLK 26 2 C9JSU1;Q9Y608-4;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 0 RGS(0.455)GDT(0.182)S(0.182)S(0.182)LIDPDTSLSELRDIYDLK 50.234 0.0057808 59886000 1649 1399.5 1602.2 1466 1620.1 1958.8 1736.6 2266.2 1529.2 1325.3 TRUE FALSE FALSE 1518.47991 1520.466544 1661.578941 1459.93408 1600.781366 1552.5228 1785.324322 2957.153948 1361.450586 1371.354076 1.107285081 1.108733747 1.211633793 1.064593095 1.167299819 1.13210937 1.301869702 2.15637522 0.992778313 1 10.4213854 -4.04979604 1.63911571 1.077209924 3.064183508 0.95806384 0.066140756 0.26549095 0.441193283 0.010541772 0.980695426 8.92E-05 4.04979604 1.986973584 up SGDEGS(ph)EDEAPSGED ddPTM_HeLa_Curcumin_4h_R1 2 SGDEGSEDEAPSGED 15 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 S(0.002)GDEGS(0.998)EDEAPSGED;S(0.028)GDEGS(0.972)EDEAPSGED ; 166.62 0.00022122 14972600 7066.8 5721.2 6176.5 6540.8 6851 7999.4 7046.7 4626 6907.7 6046.7 TRUE FALSE FALSE 6507.455323 6215.715035 6405.406523 6513.735903 6769.3063 6340.234268 7244.411437 6036.446105 6149.942592 6256.822375 1.040057546 0.993429997 1.023747541 1.041061343 1.081908019 1.013331351 1.157841953 0.964778244 0.982917881 1 12.61121443 -6.131930688 3.154916224 1.017330123 1.059110803 0.154419533 0.048906413 0.364051793 6.871795537 0.006627978 0.011534076 7.38E-07 6.131930688 0.041780681 SGDEGSEDEAPSGED ddPTM_HeLa_Curcumin_4h_R1 1 SGDEGSEDEAPSGED 15 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 0 0 148.32 0.0039202 1538500 876.3 602.62 549.08 655.52 685.73 880.61 768.24 779.03 853.77 692.62 FALSE FALSE TRUE 806.9399303 654.7077876 569.4293878 652.8076319 677.5531176 697.9615595 789.7947468 1016.552661 760.113567 716.6884934 1.125928402 0.913517928 0.794528436 0.910866629 0.945394162 0.97387019 1.102005619 1.418402374 1.060591281 1 9.485202382 -4.287940252 2.782748194 1.008192834 1.481505707 0.668333052 0.092914494 0.240439451 2.621749209 0.016194533 0.250822009 5.15E-05 4.287940252 0.473312874 YAALS(ph)DQGLDIK ddPTM_HeLa_Curcumin_4h_R1 1 YAALSDQGLDIK 12 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-4;Q8WX93-7 Q8WX93-3 PALLD Palladin 1 0 Y(0.005)AALS(0.995)DQGLDIK 115.12 0.0040649 11551000 1696.6 1584.1 1736.8 1658.8 1638.2 2220.7 1873.7 2665.8 1858.7 1500.4 TRUE FALSE FALSE 1562.31232 1721.022545 1801.167336 1651.936325 1618.665535 1760.101788 1926.270979 3478.590148 1654.80526 1552.538788 1.006295193 1.108521448 1.160143211 1.064022579 1.042592653 1.133692634 1.240723255 2.240581797 1.065870478 1 10.6004136 -4.048108235 1.720687611 1.032418889 3.253278596 0.9710083 0.059890626 0.216910403 0.398444857 0.009815749 0.936959983 8.95E-05 4.048108235 2.220859707 up SGDETPGS(ph)EVPGDKAAEEQGDDQDSEK ddPTM_HeLa_Curcumin_4h_R1 2 SGDETPGSEVPGDKAAEEQGDDQDSEK 27 1 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 0 S(0.109)GDET(0.402)PGS(0.489)EVPGDKAAEEQGDDQDSEK;S(0.166)GDET(0.185)PGS(0.648)EVPGDKAAEEQGDDQDSEK ; 91.064 2.75E-06 181121000 3748.3 3043.8 3589.7 3499.2 3506.9 4530.5 3863.8 5728.8 4160.3 3722.9 TRUE FALSE FALSE 3451.6181 3306.892509 3722.73744 3484.721238 3465.082508 3590.823231 3972.207829 7475.484748 3703.925499 3852.270498 0.895995777 0.858426871 0.96637488 0.904588927 0.899490965 0.932131644 1.031134192 1.940539937 0.961491541 1 11.91149329 -4.257654088 3.746449749 0.937168869 2.049633609 0.982870099 0.039862868 0.029671184 0.781100056 0.007067986 0.09149591 5.53E-05 4.257654088 1.11246474 SGDWVCPNPSCGNMNFAR ddPTM_HeLa_Curcumin_4h_R1 1 SGDWVCPNPSCGNMNFAR 18 0 Q92804-2;Q92804;A0A075B7D9;A0A075B7F4 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 0 0 114.76 0.0025978 11952000 1249.2 945.6 799.35 1130 1016.9 1453.6 1281.7 1255.7 1080.4 1063.6 FALSE FALSE TRUE 1150.324502 1027.33345 828.9746142 1125.324359 1004.774132 1152.106975 1317.661052 1638.557149 961.882823 1100.560021 1.045217417 0.933464265 0.753229809 1.022501579 0.912966229 1.046837022 1.197264145 1.488839426 0.873993971 1 10.10402211 -4.366382743 1.710843322 0.987993358 1.598953068 0.773192398 0.090845424 0.282947408 0.945139479 0.013113814 0.262655842 4.30E-05 4.366382743 0.61095971 SGECS(ph)PVPMGSFPR ddPTM_HeLa_Curcumin_4h_R1 1 SGECSPVPMGSFPR 14 0 P25054-2;P25054-3;P25054;A0A2Q2SV78;E9PFT7;E7EMH9 P25054-2 APC Adenomatous polyposis coli protein 1 0 S(0.007)GECS(0.988)PVPMGS(0.005)FPR 145.61 0.00062459 10530000 2209.7 1806.5 1794.7 1581 1676.1 2025.7 1368.1 742.28 1970.6 1379.1 TRUE FALSE FALSE 2034.799913 1962.64581 1861.213161 1574.458241 1656.113602 1605.546986 1406.485204 968.597755 1754.43011 1427.023622 1.425904856 1.375342202 1.304262334 1.103316172 1.160536922 1.125101898 0.985607513 0.678753834 1.229433124 1 10.4787935 -3.885925172 0.904919378 1.221299455 4.08E-17 0.686408214 0.116158818 2.500522115 0.968726362 0.026945615 3.533268013 0.000130039 3.885925172 -1.221299455 SGEHDFGAAFDGDGDR ddPTM_HeLa_Curcumin_4h_R1 2 SGEHDFGAAFDGDGDR 16 0 A0A3B3ITK7;P36871;P36871-2;P36871-3 A0A3B3ITK7 PGM1 Phosphoglucomutase-1 0 0 ; ; 139.21 0.00032005 36634000 5477.9 4513.8 4440.3 4355.3 6823.5 8444.8 5508.3 5454.7 5980.1 4266.9 FALSE FALSE TRUE 5044.318435 4903.952759 4604.861424 4337.278923 6742.134219 6693.253287 5662.848073 7117.81292 5324.097991 4415.174457 1.142495836 1.110704188 1.042962508 0.982357314 1.527036878 1.515965757 1.282587614 1.612124954 1.205863561 1 12.10825473 -5.759045338 24.99995728 1.06513882 1.472264267 0.795698953 0.099949797 19.12467038 199706.3392 0.013596249 0.026200302 1.74E-06 5.759045338 0.407125447 SGEISLPIKEEPS(ph)PISK ddPTM_HeLa_Curcumin_4h_R1 2 SGEISLPIKEEPSPISK 17 1 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2A0 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2 1 0 SGEISLPIKEEPS(0.981)PIS(0.019)K;S(0.001)GEIS(0.007)LPIKEEPS(0.905)PIS(0.087)K ; 72.316 0.0074335 178920000 2818.1 2426.08 2786.8 3144.9 2860.3 3262.5 2605.7 2249.56 2816.6 2838.78 TRUE FALSE FALSE 2595.044411 2635.779545 2890.08126 3131.887237 2826.192791 2585.820724 2678.808929 2935.440488 2507.626027 2937.427394 0.88344121 0.897308832 0.983881769 1.066200732 0.962131965 0.880301154 0.911957495 0.99932359 0.853681024 1 11.52033748 SGEIT(ph)T(ph)QKK ddPTM_HeLa_Curcumin_4h_R1 1 SGEITTQKK 9 1 Q9Y5G0-2;Q9Y5G0 Q9Y5G0-2 PCDHGB5 Protocadherin gamma-B5 2 0 S(0.001)GEIT(1)T(1)QKK 50.123 0.0096608 0 2001.8 2101.6 2209 2041.7 1962.9 2056.2 1947.5 1596.2 2109.5 2469.2 TRUE FALSE FALSE 1843.355418 2283.252939 2290.867483 2033.251986 1939.4937 1629.720942 2002.141609 2082.874032 1878.093128 2555.004516 0.721468556 0.893639493 0.896619739 0.795791934 0.759095997 0.637854427 0.783615683 0.815213444 0.735064504 1 11.31911013 -9.441552465 0.92883033 1.013767196 0.782795698 0 0.108837604 0.433969055 0.601935405 0.073573831 0.014479362 3.62E-10 9.441552465 -0.230971498 SGEQAEGS(ph)PGGPGDSQGR ddPTM_HeLa_Curcumin_4h_R1 1 SGEQAEGSPGGPGDSQGR 18 0 P38936 P38936 CDKN1A Cyclin-dependent kinase inhibitor 1 1 0 SGEQAEGS(0.999)PGGPGDS(0.001)QGR 198.6 1.53E-09 7199300 1870.2 1344.2 1671.4 1718.2 1559.3 2338.9 2060.5 1421.5 2007.5 1464.2 TRUE FALSE FALSE 1722.171697 1460.386658 1733.343554 1711.090544 1540.706366 1853.785775 2118.312084 1854.908806 1787.282273 1515.080841 1.13668634 0.963900156 1.14406011 1.129372438 1.016913635 1.223555684 1.398151192 1.224296919 1.179661325 1 10.56517906 -5.077633105 4.264208873 1.066951485 1.312512529 0.59008138 0.07793616 0.096122947 3.235468084 0.010473137 0.029033819 8.36E-06 5.077633105 0.245561044 SGEQAEGSPGGPGDS(ph)QGR ddPTM_HeLa_Curcumin_4h_R1 1 SGEQAEGSPGGPGDSQGR 18 0 P38936 P38936 CDKN1A Cyclin-dependent kinase inhibitor 1 1 0 SGEQAEGS(0.311)PGGPGDS(0.689)QGR 130.95 0.00023411 4523700 1752.5 1133.3 1366.7 1365.9 1453.6 2272.7 2062.2 1327.4 1741.3 1366.1 TRUE FALSE FALSE 1613.787776 1231.257402 1417.351104 1360.248268 1436.266769 1801.316401 2120.059782 1732.118149 1550.283747 1413.571873 1.14163829 0.87102568 1.002673533 0.962277401 1.016055 1.274301247 1.499789167 1.225348482 1.096713776 1 10.46512952 -5.1488306 3.975285062 1.037379457 1.366990269 0.70482432 0.094848893 0.103369648 2.842146606 0.014246917 0.038904406 7.10E-06 5.1488306 0.329610812 SGEQIT(ph)SSPVSPK ddPTM_HeLa_Curcumin_4h_R1 1 SGEQITSSPVSPK 13 0 A0A087WZV0;O43314-2;O43314;A0A087WWN8 A0A087WZV0 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 1 0 S(0.283)GEQIT(0.4)S(0.279)S(0.037)PVSPK 111.72 0.010671 9950700 3982.6 3027.1 3734.5 3910.7 4373.9 4446.3 3218.5 3003.9 4264.3 3611 TRUE FALSE FALSE 3667.373008 3288.749036 3872.903855 3894.51856 4321.744099 3524.08726 3308.802448 3919.775282 3796.516959 3736.481981 0.981504267 0.880172593 1.036510781 1.042295555 1.156634535 0.943156498 0.885539517 1.049055047 1.016067247 1 11.86746485 SGFGEISS(ph)PVIR ddPTM_HeLa_Curcumin_4h_R1 2 SGFGEISSPVIR 12 0 P57740;G3V1T4 P57740 NUP107 Nuclear pore complex protein Nup107 1 0 SGFGEIS(0.022)S(0.978)PVIR;SGFGEIS(0.027)S(0.973)PVIR ; 158.34 0.00026545 218298000 14257.3 12199.7 12481.6 12170.9 12525.9 18599.5 17581.7 12058.8 14739.6 11295.5 TRUE FALSE FALSE 13128.81966 13254.18771 12944.17908 12120.54004 12376.53682 14741.75404 18074.99518 15735.47261 13122.70276 11688.01778 1.123271705 1.133997907 1.10747428 1.037005612 1.05890811 1.261270672 1.54645514 1.346290954 1.122748356 1 13.51274266 -5.039309017 3.344845167 1.067911169 1.445022841 0.840002306 0.063186638 0.065202624 1.475838503 0.009694596 0.029730078 9.13E-06 5.039309017 0.377111672 SGGAPSAGVLLRRR ddPTM_HeLa_Curcumin_4h_R1 1 SGGAPSAGVLLRRR 14 2 Q00532-2 Q00532-2 0 0 60.08 0.019224 16299000 5984.8 5259 5421.2 5890.1 5792.3 7050.5 5775.6 5919.7 6975.6 5639.9 FALSE FALSE TRUE 5511.096765 5713.564526 5622.114441 5865.728327 5723.230606 5588.146824 5937.647792 7724.589279 6210.394132 5835.886105 0.944346182 0.979039759 0.963369459 1.005113572 0.980696076 0.957548986 1.01743723 1.323636058 1.064173293 1 12.51073601 -4.261060334 3.472630202 0.97485067 1.366871924 0.900832236 0.033133239 0.041991379 0.864135041 0.003140861 0.04316133 5.48E-05 4.261060334 0.392021254 GSVSQPSTPSPPKPT(ph)GIFQTSANSSFEPVK ddPTM_HeLa_Curcumin_4h_R1 1 GSVSQPSTPSPPKPTGIFQTSANSSFEPVK 30 1 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 GS(0.001)VS(0.004)QPS(0.054)T(0.117)PS(0.179)PPKPT(0.586)GIFQT(0.034)S(0.019)ANS(0.003)S(0.004)FEPVK 66.738 0.0019139 0 902.88 704.66 871.5 826.16 915.33 907.3 609.81 210.03 863.36 784.32 TRUE FALSE FALSE 831.4160953 765.5676705 903.7985566 822.7415688 904.4152876 719.1157526 626.9196274 274.0671801 768.651568 811.5750616 1.024447564 0.943310985 1.113635201 1.013759057 1.114395119 0.886074236 0.772472759 0.337697883 0.947110877 1 9.664580724 -4.21298681 1.378645032 1.019772198 7.12E-19 0.920888701 0.060615011 0.231064225 0.35146013 0.007739609 0.336564144 6.12E-05 4.21298681 -1.019772198 down NSESESNKVAAET(ph)QSPSLFGSTK ddPTM_HeLa_Curcumin_4h_R1 1 NSESESNKVAAETQSPSLFGSTK 23 1 Q9UKX7;Q9UKX7-2 Q9UKX7 NUP50 Nuclear pore complex protein Nup50 1 0 NSESESNKVAAET(0.623)QS(0.304)PS(0.072)LFGSTK 81.949 0.00039641 27866000 1188.7 760.33 1127.5 1245.5 1174.1 2209.9 2391.7 6464.5 1736.3 1112.6 TRUE FALSE FALSE 1094.613141 826.0495372 1169.286142 1240.346451 1160.099624 1751.541829 2458.804665 8435.496291 1545.832234 1151.262767 0.950793487 0.717516071 1.015655309 1.077379106 1.007675795 1.521409255 2.135745839 7.327168507 1.342727549 1 10.16900144 -4.044707342 1.684928824 0.97946881 12.73721471 0.986683225 0.216648444 0.110859924 0.193188931 0.025795807 2.495079716 9.02E-05 4.044707342 11.7577459 up SGGGGGGGGSSWGGR ddPTM_HeLa_Curcumin_4h_R1 2 SGGGGGGGGSSWGGR 15 0 Q13151 Q13151 HNRNPA0 Heterogeneous nuclear ribonucleoprotein A0 0 0 ; ; 176.32 1.68E-05 4130800 909.19 760.8 797.91 775.98 665.25 1086.16 610.11 553.9 822.93 1077.82 FALSE FALSE TRUE 837.2266521 826.5601619 827.4812465 772.7692004 657.3173282 860.8781725 627.2280446 722.7815602 732.6566379 1115.274165 0.750691335 0.741127328 0.74195321 0.692896173 0.589377347 0.771898247 0.562398076 0.648075229 0.656929624 1 10.12318269 -11.35367469 0.157784248 1.604265811 0.558093829 0 0.121623423 7.518803992 0.152465111 1.64893544 0.122114886 4.43E-12 11.35367469 -1.046171982 SGGGLHSVAEGVRLS(ph)PEPGR ddPTM_HeLa_Curcumin_4h_R1 1 SGGGLHSVAEGVRLSPEPGR 20 1 Q9NWK9-2;Q9NWK9 Q9NWK9-2 ZNHIT6 Box C/D snoRNA protein 1 1 0 SGGGLHSVAEGVRLS(1)PEPGR 57.188 0.0091978 14822000 1220.7 834.43 1045.3 1169.1 1227.6 1573.6 1295.3 996.31 1785.9 1145.6 TRUE FALSE FALSE 1124.080307 906.5544111 1084.039738 1164.262574 1212.961672 1247.217622 1331.642632 1300.080333 1589.991238 1185.409515 0.948263274 0.764760532 0.914485437 0.982160645 1.023242733 1.052140721 1.123360843 1.096735193 1.341301228 1 10.21116983 -5.375503625 1.54612349 0.952407339 1.107214658 0.057880903 0.138596901 0.299901208 1.362730925 0.011175423 0.036821965 4.21E-06 5.375503625 0.154807319 SGGGPGPSGSET(ph)PPPPR ddPTM_HeLa_Curcumin_4h_R1 2 SGGGPGPSGSETPPPPR 17 0 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 0 SGGGPGPSGS(0.012)ET(0.988)PPPPR;SGGGPGPSGSET(1)PPPPR ; 160.03 0.0004278 15065900 2828.6 3061.3 2562.3 2958.14 2491.1 3541.7 2563.3 1298.67 3666.2 3176.7 TRUE FALSE FALSE 2604.713325 3325.905131 2657.261092 2945.9 2461.395259 2807.111497 2635.219299 1694.628505 3264.027032 3287.090089 0.792407039 1.011808329 0.808393144 0.896203001 0.748806754 0.853980701 0.80168758 0.515540633 0.992983747 1 11.68259528 -3.665719951 0.724288031 0.899515219 2.68E-73 0.631156126 0.085921126 3.373165987 0.683684023 0.015717085 3.03008496 0.000215914 3.665719951 -0.899515219 SGGGPGPSGSET(ph)PPPPRR ddPTM_HeLa_Curcumin_4h_R1 2 SGGGPGPSGSETPPPPRR 18 1 P27987-2;P27987 P27987-2 ITPKB Inositol-trisphosphate 3-kinase B 1 0 SGGGPGPS(0.002)GS(0.078)ET(0.92)PPPPRR;SGGGPGPSGS(0.003)ET(0.997)PPPPRR ; 114.1 0.00027906 20335900 2025.87 1705.96 1717.88 2050.28 1984.23 1919.54 1677.62 1266.95 2149.55 1867.61 TRUE FALSE FALSE 1865.520252 1853.415581 1781.546144 2041.796485 1960.569353 1521.405766 1724.689502 1653.237223 1913.749743 1932.509308 0.965335713 0.959072007 0.921882309 1.056551953 1.014520005 0.787269567 0.892461162 0.855487327 0.990292639 1 10.91625965 -5.269909368 24.97204017 0.984031308 0.849811531 0.711210814 0.041328813 246.5289613 726841.1125 0.005888918 0.013367666 5.37E-06 5.269909368 -0.134219776 SGGGSVGAVVVKQEPLEEDS(ph)PSSSSAGLDK ddPTM_HeLa_Curcumin_4h_R1 1 SGGGSVGAVVVKQEPLEEDSPSSSSAGLDK 30 1 P15408;P15408-3;P15408-2;C9JCN8 P15408 FOSL2 Fos-related antigen 2 1 0 SGGGSVGAVVVKQEPLEEDS(0.488)PS(0.154)S(0.206)S(0.065)S(0.087)AGLDK 76.31 1.95E-05 8874700 2068.7 1179.8 1085.9 1818.8 809.86 1777.2 1374.8 1038.9 2912.6 1766.1 TRUE FALSE FALSE 1904.960212 1281.776655 1126.144409 1811.274288 800.2029484 1408.588687 1413.373188 1355.655827 2593.095067 1827.471844 1.042401949 0.701393381 0.616230785 0.991136632 0.437874297 0.770785439 0.773403537 0.741820364 1.418952131 1 10.83563346 -7.260859528 24.99889925 1.020023147 0.718744763 0.509817258 0.181705837 27.22357074 1173686.245 0.02028039 0.024050731 5.48E-08 7.260859528 -0.301278384 SGGGYGGDRSS(ph)GGGYSGDR ddPTM_HeLa_Curcumin_4h_R1 1 SGGGYGGDRSSGGGYSGDR 19 1 Q92804-2;Q92804;A0A075B7F4 Q92804-2 TAF15 TATA-binding protein-associated factor 2N 1 0 S(0.001)GGGY(0.016)GGDRS(0.209)S(0.77)GGGY(0.002)S(0.001)GDR 56.553 0.012366 28331000 2644.6 2032.8 1713.6 2142.5 1883.2 3581.8 2126.8 1317.7 2510.8 1744.8 TRUE FALSE FALSE 2435.277119 2208.506174 1777.107523 2133.634903 1860.74407 2838.894305 2186.472284 1719.460664 2235.371522 1805.43167 1.348861416 1.223256582 0.984311704 1.181786571 1.030636662 1.572418581 1.211052359 0.952382022 1.238136873 1 10.8181281 -9.614888179 1.438816808 1.000580527 1.213328963 0 0.188221688 0.607611984 2.268278933 0.122768306 0.028524197 2.43E-10 9.614888179 0.212748435 SGGIVIS(ph)PFR ddPTM_HeLa_Curcumin_4h_R1 2 SGGIVISPFR 10 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 0 SGGIVIS(1)PFR;SGGIVIS(1)PFR ; 139.32 0.0016009 29205000 6264.7 5335.4 5872.2 5888.7 6954.1 7561.9 6081.6 5876.9 5245.6 4732.9 TRUE FALSE FALSE 5768.842385 5796.568202 6089.828898 5864.33412 6871.176899 5993.4767 6252.233328 7668.739756 4670.170804 4897.367923 1.177947517 1.183608888 1.243490176 1.1974461 1.403034652 1.223815893 1.27665175 1.565890061 0.953608321 1 12.25779087 -1 0.086441836 0.783137839 2.554476378 0.768125963 0.080549739 55.21758286 0.34785119 1.006641902 11.67709354 0.1 1 1.771338539 SGGLQT(ph)PECLS(ph)REGS(ph)PIPHDPEFGSK ddPTM_HeLa_Curcumin_4h_R1 1 SGGLQTPECLSREGSPIPHDPEFGSK 26 1 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 3 0 S(0.376)GGLQT(0.988)PECLS(0.937)REGS(0.698)PIPHDPEFGSK 52.79 0.0093403 7234900 1804.8 1412.9 1198.7 1452.6 1577.4 2081.4 1585.3 1046.5 2094.8 2025.6 TRUE FALSE FALSE 1661.948176 1535.02478 1243.124876 1446.589526 1558.590535 1649.694178 1629.779251 1365.573033 1865.005681 2095.989449 0.792918197 0.732362837 0.593096915 0.690170233 0.743606098 0.787071795 0.777570351 0.651517131 0.889797266 1 11.03341574 -8.456633805 0.679985572 0.991087473 0.712718736 0.656524386 0.06467195 0.248326783 0.240091428 0.03310906 0.015466982 3.49E-09 8.456633805 -0.278368736 SGGLQTPECLS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SGGLQTPECLSR 12 0 P85037;P85037-2 P85037 FOXK1 Forkhead box protein K1 1 0 SGGLQT(0.002)PECLS(0.998)R 88.706 0.01637 161150000 1207.4 1033 1225.6 1158.6 1164.8 1144.3 564.48 647.75 1045.8 1125.8 TRUE FALSE FALSE 1111.833016 1122.287917 1271.021814 1153.80602 1150.910521 906.9592811 580.3177896 845.2459931 931.0783565 1164.921466 0.954427443 0.963402212 1.0910794 0.990458201 0.987972627 0.778558304 0.498160439 0.725581954 0.799262769 1 10.18601698 -5.072929909 3.260064925 0.986912504 0.612365012 0.729900062 0.087235997 0.058893468 1.209811607 0.008497412 0.025516991 8.45E-06 5.072929909 -0.374547493 SQS(ph)PINCIRPSVLGPLK ddPTM_HeLa_Curcumin_4h_R1 1 SQSPINCIRPSVLGPLK 17 1 Q96E09 Q96E09 FAM122A Protein FAM122A 1 0 S(0.264)QS(0.732)PINCIRPS(0.004)VLGPLK 58.824 0.016201 38902000 2051.4 1431 1910.2 1785.3 1904.1 2162.8 1447.7 464.48 1953.6 1594.5 TRUE FALSE FALSE 1889.029525 1554.689264 1980.993692 1777.912902 1881.394851 1714.2109 1488.318566 606.0978138 1739.294968 1649.908756 1.144929693 0.942288025 1.200668634 1.07758256 1.140302362 1.038973151 0.902061135 0.367352323 1.054176457 1 10.68817053 -4.211686751 1.966203845 1.075322941 0.094600657 0.901725453 0.070298354 0.204212921 0.744502158 0.010728826 0.376383071 6.14E-05 4.211686751 -0.980722284 down SGGMSNELNNIISR ddPTM_HeLa_Curcumin_4h_R1 1 SGGMSNELNNIISR 14 0 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 0 0 92.65 0.014682 2037200 657.09 652.63 505.35 611.49 827.66 863.61 692.61 697.07 865.74 675.99 FALSE FALSE TRUE 605.0806331 709.0404291 524.0787156 608.9598164 817.7906951 684.4875511 712.0427725 909.6034341 770.770488 699.4806022 0.865042764 1.013667037 0.749239813 0.870588569 1.16913992 0.978565451 1.017959283 1.300398369 1.101918317 1 9.450140239 -1 0.706040238 0.931101316 47.30235812 0.411932819 0.115691657 175.5839242 0.849201228 0.017527251 12884.15851 0.1 1 46.37125681 SGIETFS(ph)PPPPPPK ddPTM_HeLa_Curcumin_4h_R1 2 SGIETFSPPPPPPK 14 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 0 S(0.001)GIET(0.154)FS(0.845)PPPPPPK;S(0.01)GIET(0.351)FS(0.639)PPPPPPK ; 92.295 0.0086776 25195000 7643.9 6062.6 7226.8 7286.9 6641.4 9559.4 7762.3 5104.2 7762.7 6862.4 TRUE FALSE FALSE 7038.877249 6586.62413 7494.631565 7256.748739 6562.205643 7576.672683 7980.089247 6660.447083 6911.151231 7100.867889 0.991269991 0.927580154 1.055452894 1.021952366 0.924141351 1.067006569 1.123818859 0.937976482 0.97328261 1 12.79377965 -5.208224719 24.99991169 0.992985025 1.05102249 0.165035404 0.05703783 404.6062819 190080.5047 0.007260312 0.018510221 6.19E-06 5.208224719 0.058037465 KPVTVSPTTPTS(ph)PTEGEAS ddPTM_HeLa_Curcumin_4h_R1 1 KPVTVSPTTPTSPTEGEAS 19 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 0 KPVTVSPT(0.001)T(0.007)PT(0.256)S(0.715)PT(0.017)EGEAS(0.004) 77.726 0.0084 16157000 2494.2 2089 2530.3 2802.3 2487 4006 4821.7 8417.9 2835.9 2377.5 TRUE FALSE FALSE 2296.781438 2269.563852 2624.075144 2790.704825 2457.344149 3175.110443 4956.983925 10984.47896 2524.808865 2460.117948 0.933606228 0.922542699 1.066646071 1.134378466 0.998872494 1.290633421 2.014937507 4.465021268 1.02629586 1 11.26451177 -4.030078362 1.368244084 0.983031051 7.667296663 0.994930856 0.073989134 0.104768851 0.114216681 0.011508344 1.119948059 9.33E-05 4.030078362 6.684265612 up SGK(ac)FMNPTDQAR ddPTM_HeLa_Curcumin_4h_R1 6 SGKFMNPTDQAR 12 1 F5H5G4;F5GXS9;Q9Y2W2 F5H5G4;Q9Y2W2 WBP11 WW domain-binding protein 11 0 1 ;;;;; SGK(1)FMNPTDQAR;SGK(1)FMNPTDQAR;SGK(1)FMNPTDQAR;SGK(1)FMNPTDQAR;SGK(1)FMNPTDQAR;SGK(1)FMNPTDQAR 155.47 2.22E-05 112763600 11664.57 9186.75 10100.84 7872.73 8880.86 13880.5 9061.36 6651.67 10846.06 10022.75 FALSE TRUE FALSE 10741.30698 9980.811735 10475.18602 7840.154729 8774.961545 11001.52783 9315.597374 8679.733562 9656.274354 10371.03982 1.035702029 0.962373292 1.010042021 0.75596612 0.846102387 1.060793134 0.898231763 0.836920281 0.931080637 1 13.34027293 -6.450797163 24.99938307 1.011956766 0.888258616 0.297255194 0.078414266 117.0757754 40603.96149 0.011552569 0.017646838 3.54E-07 6.450797163 -0.123698151 SGK(ac)K(ac)GQASLYGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 SGKKGQASLYGKR 13 3 Q92922 Q92922 SMARCC1 SWI/SNF complex subunit SMARCC1 0 3 SGK(1)K(1)GQASLYGK(1)R 159.52 7.12E-05 1289600 342.93 220.67 358.86 235.94 325.9 454.72 61.651 515.81 259.53 192.97 FALSE TRUE FALSE 315.7867286 239.7437315 372.1596673 234.9637428 322.0138554 360.4059462 63.38076113 673.0780945 231.0602083 199.6756931 1.581498097 1.200665578 1.863820585 1.176726817 1.6126843 1.80495653 0.317418511 3.370856432 1.157177444 1 7.641514912 -1.000000297 0.048865031 6.13E-10 4.307441962 0.141844519 0.699649483 776.3294051 2.896594659 62.07268612 255.9987745 0.099999932 1.000000297 4.307441961 SGK(ac)LPSGVSAK ddPTM_HeLa_Curcumin_4h_R1 1 SGKLPSGVSAK 11 1 Q5JTH9-2;Q5JTH9-3;Q5JTH9;A0A087WYW2;H7C1M8;A0A087X1U8 Q5JTH9-2 RRP12 RRP12-like protein 0 1 SGK(1)LPSGVSAK 87.667 0.0078114 0 1612.1 2194.8 1859.3 1556.7 1752.1 2618.4 1818.8 1018.9 2254.2 1706.9 FALSE TRUE FALSE 1484.500584 2384.508732 1928.207294 1550.258788 1731.207352 2075.314325 1869.830633 1329.55792 2006.9199 1766.214648 0.840498399 1.350067352 1.091717417 0.87772955 0.980179478 1.175006858 1.058665568 0.752772559 1.136283125 1 10.78644497 SGKLK(ac)GDDLQAIKK ddPTM_HeLa_Curcumin_4h_R1 1 SGKLKGDDLQAIKK 14 3 P07910;P07910-2;G3V2Q1;G3V4C1;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7;G3V576 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 0 1 SGK(0.049)LK(0.951)GDDLQAIKK 95.981 0.0022 19742000 7381.4 6080.1 6228 5803 5607.5 8603.7 6578.4 6114.4 7912.2 6874.7 FALSE TRUE FALSE 6797.154401 6605.636752 6458.815159 5778.988724 5540.634225 6819.195636 6762.972199 7978.652413 7044.251455 7113.595313 0.955516037 0.928593273 0.907953696 0.812386489 0.778879593 0.958614503 0.950710843 1.121606173 0.990251925 1 12.79636319 -7.705730235 1.213466393 0.987483059 0.914727439 0.091756429 0.086932841 0.700920863 2.139831803 0.020751583 0.020035957 1.97E-08 7.705730235 -0.07275562 SGKNSQEDS(ph)EDS(ph)EDKDVK ddPTM_HeLa_Curcumin_4h_R1 2 SGKNSQEDSEDSEDKDVK 18 2 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 2 0 S(0.001)GKNS(0.019)QEDS(0.982)EDS(0.998)EDKDVK;S(0.001)GKNS(0.017)QEDS(0.981)EDS(1)EDKDVK ; 64.619 0.015071 58660000 8531.3 5568.7 4742.9 6996.3 3141.3 6839.5 5311.2 6509.2 13500.7 10674.2 TRUE FALSE FALSE 7856.038603 6050.033614 4918.676046 6967.351164 3103.842049 5420.910603 5460.217978 8493.825115 12019.70699 11045.12766 0.711267343 0.54775588 0.445325414 0.630807663 0.281014593 0.490796555 0.494355353 0.769011041 1.088236131 1 13.43112247 -8.03242534 0.668548906 0.971473207 0.500380392 0.70449952 0.129865888 0.254044495 0.254293734 0.049360604 0.032903619 9.28E-09 8.03242534 -0.471092815 SGKNSQEDS(ph)EDSEDKDVK ddPTM_HeLa_Curcumin_4h_R1 1 SGKNSQEDSEDSEDKDVK 18 2 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 SGKNS(0.042)QEDS(0.917)EDS(0.041)EDKDVK 88.555 0.0024354 6521400 1592.2 719.94 723.12 919.03 445.22 992.63 777.93 815.87 1849.1 1428.8 TRUE FALSE FALSE 1466.17569 782.1684056 749.9194633 915.2272974 439.9110423 786.7473488 799.7566221 1064.625007 1646.258356 1478.450694 0.991697387 0.529045986 0.507233326 0.619044856 0.297548673 0.532143109 0.54094237 0.720095037 1.113502373 1 10.52987042 -7.262255072 8.498363341 0.996243503 0.528061941 0.821894608 0.106149498 0.030222836 29.68654376 0.016250662 0.019200225 5.47E-08 7.262255072 -0.468181561 SGKNSQEDSEDS(ph)EDKDVK ddPTM_HeLa_Curcumin_4h_R1 1 SGKNSQEDSEDSEDKDVK 18 2 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 SGKNSQEDS(0.324)EDS(0.676)EDKDVK 75.868 0.0066356 4082200 830.73 467.57 395.87 581.07 302.68 651.89 470.34 401.83 863.85 957.77 TRUE FALSE FALSE 764.9768439 507.9846673 410.5412904 578.6656863 299.0707387 516.6806657 483.5364745 524.3461172 769.0878162 991.0524362 0.771883319 0.512570928 0.414247799 0.58389008 0.301770853 0.521345437 0.487902009 0.529080095 0.776031407 1 9.952817582 -7.589917095 0.939999904 0.946719299 0.461017202 0.739072627 0.098869906 0.122407166 0.224173638 0.021283358 0.021160922 2.57E-08 7.589917095 -0.485702097 SGKYDLDFK ddPTM_HeLa_Curcumin_4h_R1 1 SGKYDLDFK 9 1 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 0 80.916 0.019445 31219000 10519 8611 9537.7 9770.2 10503 15190 13159 13974 10863 10085 FALSE FALSE TRUE 9686.41005 9355.29647 9891.175552 9729.773501 10377.75858 12039.42277 13528.20612 18234.60827 9671.356078 10435.453 0.928221329 0.896491649 0.947843429 0.932376726 0.994471307 1.153703895 1.296369801 1.747371031 0.926778749 1 13.34920561 -4.004618521 0.952590994 0.954586708 2.520954437 0.980215169 0.035325703 0.334453219 0.166763009 0.006559909 0.603810637 9.89E-05 4.004618521 1.566367729 SGKYDLDFK(ac)SPDDPSR ddPTM_HeLa_Curcumin_4h_R1 2 SGKYDLDFKSPDDPSR 16 2 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 1 ; SGKYDLDFK(1)SPDDPSR;SGKYDLDFK(1)SPDDPSR 100.68 0.0016751 8025700 4814.3 5191.7 4146.1 4320.4 5681.9 12819.4 7990.3 10036.8 12298.4 4836.7 FALSE TRUE FALSE 4433.243075 5640.447414 4299.758113 4302.52333 5614.147053 10160.51194 8214.486313 13096.97412 10949.29629 5004.774965 0.88580268 1.127013193 0.859131158 0.859683674 1.12175814 2.030163595 1.641329804 2.616895706 2.187769953 1 12.28908949 -4.850987133 0.977907809 0.937397117 2.586532966 0.444869277 0.453620512 0.241087203 0.303592648 0.03244597 0.335741519 1.41E-05 4.850987133 1.649135848 SGLCS(ph)PSYVAVTPFSLR ddPTM_HeLa_Curcumin_4h_R1 2 SGLCSPSYVAVTPFSLR 17 0 H0YBT0;A0A087WUS5;P01106;P01106-2;H0YBG3;A0A0B4J1R1 H0YBT0 MYC Myc proto-oncogene protein 1 0 S(0.015)GLCS(0.84)PS(0.144)YVAVTPFSLR;S(0.01)GLCS(0.479)PS(0.479)Y(0.031)VAVT(0.001)PFSLR ; 154.51 0.00018308 62194000 3252.7 2647.77 2949 2824.5 2463.34 4319.5 2084.98 922.26 3041.1 2369.48 TRUE FALSE FALSE 2995.245363 2876.631441 3058.292534 2812.812967 2433.966279 3423.587009 2143.478927 1203.452828 2707.498938 2451.819254 1.221641994 1.173264072 1.247356439 1.147235043 0.992718479 1.396345593 0.874240189 0.490840761 1.10428162 1 11.25963691 -4.429497841 3.55257494 1.132981849 0.50230076 0.755465862 0.117344915 0.101319655 2.165360603 0.017596885 0.12731331 3.72E-05 4.429497841 -0.63068109 SGLEELVLSEMNS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 SGLEELVLSEMNSPSR 16 0 A0A087WXA6;A0A087WT45;Q4V328-4;Q4V328;Q4V328-2;Q4V328-3 A0A087WXA6;Q4V328-3 GRIPAP1 GRIP1-associated protein 1 1 0 SGLEELVLSEMNS(0.986)PS(0.014)R;SGLEELVLS(0.001)EMNS(0.993)PS(0.006)R ; 113.67 0.0015741 25528000 6647.1 4939.3 5190.4 5228.6 5427.4 8597.3 7411.2 2774.22 5779.3 4573.3 TRUE FALSE FALSE 6120.975021 5366.231083 5382.76079 5206.965439 5362.6818 6814.123068 7619.138326 3620.066907 5145.325249 4732.221835 1.293467474 1.133977077 1.137470089 1.100321502 1.133227052 1.439941598 1.61005519 0.764982504 1.087295868 1 12.20830199 -9.442195045 1.047883353 0.993541681 1.220613036 0.07047215 0.21343966 0.926574223 1.73441477 0.162928236 0.036226062 3.61E-10 9.442195045 0.227071355 SGLEPAS(ph)SPSK ddPTM_HeLa_Curcumin_4h_R1 1 SGLEPASSPSK 11 0 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 SGLEPAS(0.624)S(0.373)PS(0.002)K 149.49 0.00067284 79927000 8753.4 7528.1 8367 8427.2 9687.5 9047.2 7557.1 2850.5 7705.5 6438.6 TRUE FALSE FALSE 8060.559153 8178.795419 8677.08838 8392.330479 9571.98289 7170.708737 7769.131887 3719.604328 6860.225928 6662.340871 1.20986892 1.227615875 1.30240835 1.259666931 1.436729683 1.076304692 1.166126447 0.558302915 1.029702031 1 12.70181345 -4.260967749 24.60011529 1.158115374 0.558302684 0.680182315 0.128263592 16.63764552 867478.0575 0.020493053 0.162273744 5.48E-05 4.260967749 -0.59981269 SGLEPAS(ph)SPSKGSEPR ddPTM_HeLa_Curcumin_4h_R1 2 SGLEPASSPSKGSEPR 16 1 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 S(0.001)GLEPAS(0.498)S(0.498)PS(0.004)KGSEPR;SGLEPAS(0.916)S(0.083)PSKGSEPR ; 215.93 3.44E-14 55034300 6699.9 5559.9 6381.5 6374.2 6988.3 7299 5699.6 1860.24 5965 4964.3 TRUE FALSE FALSE 6169.595845 6040.472982 6618.004004 6347.825249 6904.969087 5785.105123 5859.515436 2427.418613 5310.654424 5136.809055 1.201056099 1.175919314 1.288349232 1.23575262 1.344213696 1.126205989 1.140691697 0.472553795 1.033843066 1 12.32665673 -4.261391749 8.094571393 1.145554255 0.467398553 0.803602131 0.102972838 0.037182866 30.96315941 0.017252875 0.136744988 5.48E-05 4.261391749 -0.678155702 SGLEPASS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 SGLEPASSPSK 11 0 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 SGLEPAS(0.123)S(0.857)PS(0.02)K 96.604 0.013162 147730000 7882.3 6453 7494.4 7345.9 7802.8 7898.7 7780.6 3085.8 6277.1 5360.8 TRUE FALSE FALSE 7258.407638 7010.768566 7772.149057 7315.504612 7709.756706 6260.420583 7998.902696 4026.646215 5588.517835 5547.087401 1.308507891 1.26386481 1.401122516 1.318801036 1.389874748 1.128595988 1.44200048 0.725902789 1.007468863 1 12.43751474 -9.263822654 0.953186779 0.997308169 1.264401992 0.194268571 0.195003628 0.683191068 1.095943939 0.126333137 0.033083999 5.45E-10 9.263822654 0.267093823 SGLNGS(ph)ILAER ddPTM_HeLa_Curcumin_4h_R1 1 SGLNGSILAER 11 0 Q96H22-5;Q96H22-4;Q96H22;Q96H22-3 Q96H22-5 CENPN Centromere protein N 1 0 S(0.167)GLNGS(0.833)ILAER 93.228 0.015223 11427000 1908.3 1701.6 1836.7 1696.6 2413.3 2354.8 1883.8 1179.3 1674.8 1880.7 TRUE FALSE FALSE 1757.256041 1848.678722 1904.769718 1689.579919 2384.522974 1866.387936 1936.654358 1538.863141 1491.07863 1946.054185 0.902984128 0.949962615 0.978785551 0.868208055 1.225311706 0.959062677 0.995169802 0.790760685 0.766206122 1 10.92633617 -4.776632039 0.001681337 1.876611617 0.036247133 0 0.123880847 2873171.479 898.9071286 486970.8684 496994.7697 1.67E-05 4.776632039 -1.840364484 SGLNGS(ph)ILAEREEPLR ddPTM_HeLa_Curcumin_4h_R1 1 SGLNGSILAEREEPLR 16 1 Q96H22-5;Q96H22-4;Q96H22;Q96H22-3 Q96H22-5 CENPN Centromere protein N 1 0 S(0.001)GLNGS(0.999)ILAEREEPLR 121.82 0.007897 3398200 1927 1474 1490.8 1657.2 1410.9 1632.1 1360.4 922.34 2118.7 1543.2 TRUE FALSE FALSE 1774.475917 1601.405992 1546.050359 1650.342946 1394.075939 1293.584062 1398.569163 1203.55722 1886.283911 1596.826085 1.111251835 1.002868131 0.968202094 1.03351452 0.873029287 0.810097026 0.875843134 0.753718411 1.181270727 1 10.64099148 -5.680317093 1.06737997 1.048650496 0.798952154 0.749340685 0.063409366 0.187745585 0.409657086 0.009225986 0.029723173 2.09E-06 5.680317093 -0.249698342 SGLQLSLEQGTGENS(ph)FR ddPTM_HeLa_Curcumin_4h_R1 2 SGLQLSLEQGTGENSFR 17 0 P23497;E9PHV6;P23497-7;P23497-6;P23497-2;P23497-3;P23497-4;P23497-5;C9JBL0 P23497 SP100 Nuclear autoantigen Sp-100 1 0 SGLQLSLEQGT(0.002)GENS(0.998)FR;SGLQLSLEQGTGENS(1)FR ; 225.17 2.85E-18 15167900 3879.9 3528.7 3762.6 3517.7 3322.9 5360 3857.5 2867.5 4453.4 3691.9 TRUE FALSE FALSE 3572.801821 3833.705104 3902.045266 3503.144689 3283.276588 4248.27558 3965.731068 3741.78755 3964.873162 3820.19325 0.935241122 1.003536956 1.021426145 0.917007193 0.85945301 1.112057768 1.038096978 0.979475986 1.037872406 1 11.89942991 -5.243896451 24.99808797 0.965011157 1.042698904 0.257070776 0.058619113 842.2606296 1200191.587 0.007896114 0.02007889 5.70E-06 5.243896451 0.077687747 SGLS(ph)LEELR ddPTM_HeLa_Curcumin_4h_R1 1 SGLSLEELR 9 0 A0A087WWA3;Q4R9M9;O60333-2;O60333;O60333-4 A0A087WWA3 KIF1B;KIF1Bbeta Kinesin-like protein;Kinesin-like protein KIF1B 1 0 SGLS(1)LEELR 138.25 0.0026229 44265000 3898.8 3541.6 3463.3 4119.4 3936.3 4103.1 3279.6 3548.8 4404.7 3782 TRUE FALSE FALSE 3590.205866 3847.720123 3591.652945 4102.355014 3889.362193 3252.070809 3371.616749 4630.812783 3921.51543 3913.424218 0.917407791 0.983210587 0.917777564 1.048277617 0.993851414 0.831003905 0.861551562 1.183314797 1.002067553 1 11.93421579 -4.246320987 24.23852406 0.953241322 1.183315051 0.536635778 0.064838519 1147.893262 1840311.137 0.009175466 0.277038002 5.67E-05 4.246320987 0.230073729 SGLTVPT(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 2 SGLTVPTSPK 10 0 Q53EL6;Q53EL6-2;Q5VZS7 Q53EL6 PDCD4 Programmed cell death protein 4 1 0 SGLTVPT(0.913)S(0.087)PK;SGLTVPT(0.93)S(0.07)PK ; 163.9 0.0017174 747050000 35434 28095 29366 29394 29286 30837 25070 18540.3 33998 29480 TRUE FALSE FALSE 32629.36151 30523.40661 30454.32979 29272.37542 28936.78358 24441.0586 25773.39673 24193.15212 30268.50446 30504.42781 1.069659845 1.000622166 0.998357681 0.959610703 0.948609289 0.801229866 0.844906742 0.793102964 0.992265931 1 14.89673105 -5.545928257 1.002275457 1.030865996 0.796673566 0.88318693 0.030675406 0.139139813 0.255806677 0.005529298 0.02138476 2.84E-06 5.545928257 -0.23419243 SGMNVAR ddPTM_HeLa_Curcumin_4h_R1 1 SGMNVAR 7 0 P14618;H3BU13;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 113.7 0.01147 11463000 5022.4 4470.8 4919.4 3389.1 3967.5 6179.2 3883.6 3577.9 3962.1 4285.6 FALSE FALSE TRUE 4624.87174 4857.236031 5101.717292 3375.076802 3920.190154 4897.564266 3992.563364 4668.785239 3527.467543 4434.524281 1.042923986 1.095322908 1.150454247 0.761091064 0.884015941 1.104417059 0.900336341 1.052826627 0.795455683 1 12.11456363 -6.295283825 24.9959971 1.036483761 0.944268181 0.076060299 0.123476812 834.9372484 616645.8707 0.014946666 0.022832178 5.07E-07 6.295283825 -0.09221558 SGNQVSEFISNTFLDKQHEVEIPS(ph)PTQK ddPTM_HeLa_Curcumin_4h_R1 2 SGNQVSEFISNTFLDKQHEVEIPSPTQK 28 1 A0A1B0GW84;A0A087WSZ7;Q08499-2;Q08499-10;Q08499-9;Q08499-11;Q08499;D6RHE0;Q08499-5;Q08499-4;Q08499-3;Q08499-6;Q08499-8 A0A1B0GW84;Q08499-6;Q08499-8 PDE4D "cAMP-specific 3,5-cyclic phosphodiesterase 4D" 1 0 SGNQVSEFISNTFLDKQHEVEIPS(0.871)PT(0.129)QK;SGNQVSEFISNTFLDKQHEVEIPS(0.95)PT(0.05)QK ; 87.457 1.49E-06 98009000 7076.2 5561.9 6364.8 6419.9 6018.8 8885.5 5835 4238.6 7176.2 6233.1 TRUE FALSE FALSE 6516.111303 6042.645853 6600.685087 6393.336155 5947.029741 7042.54714 5998.714396 5530.929628 6388.988814 6449.699761 1.010296842 0.936887929 1.023409667 0.99126105 0.922063036 1.091918601 0.930076534 0.857548387 0.990587012 1 12.65501629 -4.527158814 24.91620371 0.999613467 0.87568039 0.489588689 0.044305025 50.85171674 296034.0201 0.00548457 0.020698514 2.97E-05 4.527158814 -0.123933077 SGNQVSEFISNTFLDKQHEVEIPS(ph)PTQKEK ddPTM_HeLa_Curcumin_4h_R1 2 SGNQVSEFISNTFLDKQHEVEIPSPTQKEK 30 2 A0A1B0GW84;A0A087WSZ7;Q08499-2;Q08499-10;Q08499-9;Q08499-11;Q08499;D6RHE0;Q08499-5;Q08499-4;Q08499-3;Q08499-6;Q08499-8 A0A1B0GW84;Q08499-6;Q08499-8 PDE4D "cAMP-specific 3,5-cyclic phosphodiesterase 4D" 1 0 SGNQVSEFISNTFLDKQHEVEIPS(0.801)PT(0.199)QKEK;SGNQVSEFISNTFLDKQHEVEIPS(0.915)PT(0.084)QKEK ; 62.028 0.00037654 31833000 2055.13 1641.03 1693.87 1677.15 1343.73 2475.6 1662.76 1383.27 2889.3 2177.53 TRUE FALSE FALSE 1892.464292 1782.873321 1756.646312 1670.210398 1327.706897 1962.132654 1709.412571 1805.022655 2572.351019 2253.199005 0.839901086 0.79126314 0.779623241 0.741261821 0.589254164 0.870820842 0.758660272 0.801093313 1.141643953 1 11.13775902 -8.247100634 0.563947518 0.997395145 0.750234819 0.655904178 0.083693281 0.358992334 0.253348056 0.039018693 0.019811587 5.66E-09 8.247100634 -0.247160326 SGNVAELALK ddPTM_HeLa_Curcumin_4h_R1 2 SGNVAELALK 10 0 P49321-4;P49321;P49321-3;H0YDS9;E9PRH9;H0YF33;Q5T624;P49321-2 P49321-4 NASP Nuclear autoantigenic sperm protein 0 0 ; ; 100.69 0.0033005 3267300 4618.3 3568.6 4023.7 4328.1 4230.9 5197.1 4189.7 3989.4 4238.4 4161.9 FALSE FALSE TRUE 4252.756682 3877.053883 4172.821862 4310.191469 4180.449281 4119.162877 4307.251706 5205.749695 3773.458124 4306.525715 0.987514522 0.900274174 0.968953197 1.000851209 0.970724328 0.956493273 1.000168579 1.208804972 0.876218644 1 12.07230873 -4.264020584 4.416874188 0.982145634 1.224190758 0.724215283 0.044264776 0.05930967 2.824616608 0.004328962 0.044551007 5.44E-05 4.264020584 0.242045124 SGNWES(ph)SEGWGAQPEGAGAQR ddPTM_HeLa_Curcumin_4h_R1 2 SGNWESSEGWGAQPEGAGAQR 21 0 Q9Y5X1 Q9Y5X1 SNX9 Sorting nexin-9 1 0 S(0.003)GNWES(0.904)S(0.093)EGWGAQPEGAGAQR;S(0.271)GNWES(0.626)S(0.103)EGWGAQPEGAGAQR ; 139.78 3.23E-05 12851100 1196.75 1023.75 1364.14 1194.04 1057.85 1418.01 979.02 871.59 1131.89 1066.22 TRUE FALSE FALSE 1102.025975 1112.238388 1414.696228 1189.099379 1045.23583 1123.898742 1006.488666 1137.333779 1007.724499 1103.271066 0.998871455 1.008127941 1.282274386 1.077794402 0.94739712 1.018696834 0.912276863 1.030874292 0.913397016 1 10.10757158 -3.846466906 19.48089305 1.016077923 15.53210541 0.001332799 0.100662399 8493.623675 1079625.792 0.013118326 9832.438838 0.000142408 3.846466906 14.51602748 SGPEAEGLGSETSPT(ph)VDDEEEMLYGDSGSLFSPSKEEARR ddPTM_HeLa_Curcumin_4h_R1 1 SGPEAEGLGSETSPTVDDEEEMLYGDSGSLFSPSKEEARR 40 2 Q10570 Q10570 CPSF1 Cleavage and polyadenylation specificity factor subunit 1 1 0 SGPEAEGLGS(0.047)ET(0.045)S(0.042)PT(0.173)VDDEEEMLY(0.162)GDS(0.173)GS(0.173)LFS(0.173)PS(0.011)KEEARR 46.034 0.0030348 5135300 751.98 435.01 682.66 692.35 464.33 816.21 461.36 292.1 951.39 634.65 TRUE FALSE FALSE 692.4599895 472.610326 707.9599801 689.4852391 458.793168 646.9188454 474.3045199 381.1599453 847.0248973 656.7040403 1.054447585 0.719670197 1.078050289 1.049917766 0.698630037 0.985099536 0.722250041 0.580413584 1.289812222 1 9.359099521 -3.628015425 0.473230989 1.014972243 1.96E-13 0.466829825 0.155041383 4.332521538 0.424859797 0.026286567 2.799190682 0.000235497 3.628015425 -1.014972243 SGPEAEGLGSETSPTVDDEEEMLYGDSGS(ph)LFSPSKEEARR ddPTM_HeLa_Curcumin_4h_R1 3 SGPEAEGLGSETSPTVDDEEEMLYGDSGSLFSPSKEEARR 40 2 Q10570 Q10570 CPSF1 Cleavage and polyadenylation specificity factor subunit 1 1 0 SGPEAEGLGSETSPT(0.001)VDDEEEMLY(0.011)GDS(0.135)GS(0.421)LFS(0.34)PS(0.09)KEEARR;SGPEAEGLGS(0.001)ET(0.001)S(0.002)PT(0.027)VDDEEEMLY(0.023)GDS(0.138)GS(0.381)LFS(0.312)PS(0.115)KEEARR;SGPEAEGLGS(0.006)ET(0.009)S(0.023)PT(0.202)VDDEEEMLY(0.186)GDS(0.074)GS(0.24)LFS(0.24)PS(0.02)KEEARR ;; 64.685 1.21E-05 24442500 3874.3 2840.49 2699.26 3263.95 2664.86 4197.2 3367.55 2500.51 4361.2 4404.6 TRUE FALSE FALSE 3567.645067 3086.009299 2799.29695 3250.44464 2633.083285 3326.653408 3462.03439 3262.903988 3882.787271 4557.659522 0.782780076 0.677103957 0.614196154 0.713182857 0.577727071 0.729903889 0.759607946 0.715916573 0.851925698 1 12.15407744 -8.350326274 0.685193815 0.986783911 0.681777559 0.635647827 0.068772006 0.204832218 0.205782475 0.028949198 0.014951494 4.46E-09 8.350326274 -0.305006352 SGPKPFSAPKPQT(ph)SPSPK ddPTM_HeLa_Curcumin_4h_R1 1 SGPKPFSAPKPQTSPSPK 18 2 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 0 SGPKPFSAPKPQT(0.926)S(0.072)PS(0.002)PK 77.027 0.017193 20070000 2016.7 3578.6 1684.8 2345 1731 2244.4 1423.5 1092.8 2270.1 2212.8 TRUE FALSE FALSE 1857.076067 3887.918238 1747.24017 2335.297011 1710.358956 1778.88614 1463.439579 1425.989689 2021.07571 2289.694635 0.8110584 1.698007314 0.763088729 1.019916357 0.746981248 0.776909773 0.639141812 0.622785968 0.882683515 1 11.16093949 -5.444820256 1.505624597 0.969939602 0.646676063 0.280172504 0.250459159 0.489508233 2.132658497 0.03835308 0.120763367 3.59E-06 5.444820256 -0.323263538 SGPKPFSAPKPQT(ph)SPSPKR ddPTM_HeLa_Curcumin_4h_R1 1 SGPKPFSAPKPQTSPSPKR 19 3 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 0 SGPKPFS(0.019)APKPQT(0.431)S(0.118)PS(0.431)PKR 42.78 0.019798 375560000 1170.7 925.15 898.98 1311.6 1027.9 1315.3 1297 776.5 1292.3 1265.3 TRUE FALSE FALSE 1078.03786 1005.115844 932.2969896 1306.172947 1015.642964 1042.491954 1333.390329 1013.251275 1150.537923 1309.269081 0.823389077 0.767692339 0.712074396 0.997635219 0.775732795 0.796239649 1.018423446 0.77390606 0.878763533 1 10.35454591 -9.136857447 0.931114752 0.9984393 0.836227027 0.107707636 0.100856932 0.545197002 0.864641713 0.057697449 0.017384531 7.30E-10 9.136857447 -0.162212274 SGPKPFSAPKPQTS(ph)PS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SGPKPFSAPKPQTSPSPK 18 2 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 2 0 SGPKPFSAPKPQT(0.567)S(0.618)PS(0.815)PK 66.3 0.012949 427140000 3639 3057.6 3344.1 3523.5 2866.8 3683.2 2484.5 2649.4 3403.3 3094.9 TRUE FALSE FALSE 3350.96931 3321.88532 3468.035288 3508.920691 2832.615282 2919.262802 2554.208383 3457.189864 3029.966505 3202.447545 1.046377579 1.037295779 1.082932738 1.095699661 0.884515747 0.911572402 0.797580085 1.079546133 0.94614087 1 11.64495922 -5.750572844 24.9998592 1.033391865 0.909199664 0.359587263 0.075723166 153.2347774 352533.8283 0.009672515 0.019192099 1.78E-06 5.750572844 -0.124192201 SGPKPFSAPKPQTSPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SGPKPFSAPKPQTSPSPK 18 2 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 1 0 SGPKPFSAPKPQT(0.083)S(0.364)PS(0.553)PK;SGPKPFSAPKPQT(0.033)S(0.165)PS(0.802)PK ; 126.3 0.00016064 4173200000 7302.2 5736.7 7043.5 6425.2 6808.7 8085.1 6657.7 3513.1 7731 6975.9 TRUE FALSE FALSE 6724.223165 6232.554786 7304.538306 6398.614225 6727.510699 6408.159122 6844.497144 4584.228018 6882.928642 7218.312006 0.931550639 0.863436601 1.011945494 0.886441902 0.932006083 0.887764219 0.948212981 0.635083107 0.953537148 1 12.81744579 -3.826565046 1.73238646 0.951502831 5.50E-12 0.758357876 0.049486326 1.413316549 1.491815586 0.007539627 3.237390724 0.000149085 3.826565046 -0.951502831 SGPKPFSAPKPQTSPSPK ddPTM_HeLa_Curcumin_4h_R1 1 SGPKPFSAPKPQTSPSPK 18 2 Q01518-2;Q01518 Q01518-2 CAP1 Adenylyl cyclase-associated protein 1 0 0 68.576 0.0058036 4072200 1936.4 1476.6 1872.5 1810.3 1538.6 2668.2 2012.4 3861.4 2277 1926.6 FALSE FALSE TRUE 1783.131897 1604.230724 1941.896497 1802.809458 1520.2532 2114.785243 2068.862528 5038.723084 2027.218797 1993.549207 0.894450907 0.804710874 0.974090076 0.904321525 0.762586243 1.060814168 1.037778511 2.527513777 1.01688927 1 10.9611235 -4.253747727 3.983324457 0.932277254 2.684479761 0.966995135 0.088209751 0.030348528 0.980284105 0.012263921 0.154482305 5.58E-05 4.253747727 1.752202507 up SGPLFNFDVHDDVR ddPTM_HeLa_Curcumin_4h_R1 1 SGPLFNFDVHDDVR 14 0 B0S8I6;Q14320 B0S8I6 FAM50A Protein FAM50A 0 0 119.45 0.0014652 6711400 2185.6 2056.7 2018.6 1989.2 1976.1 3160.1 2096.3 2036 2432.6 2090.1 FALSE FALSE TRUE 2012.607454 2234.471984 2093.411092 1980.969217 1952.536298 2504.659638 2155.116536 2656.767027 2165.749866 2162.730819 0.930586199 1.033171564 0.967948056 0.915957363 0.902810595 1.158100498 0.99647932 1.228431668 1.001395942 1 11.0786384 -5.257353033 24.99891521 0.963986371 1.114551382 0.560140911 0.065931663 200.8886194 1228963.298 0.008761684 0.021474708 5.53E-06 5.257353033 0.150565011 SGPPS(ph)PPSTATSFGGPRPR ddPTM_HeLa_Curcumin_4h_R1 3 SGPPSPPSTATSFGGPRPR 19 1 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2;A0A087X0E3 A0A0A0MS59 SRCAP Helicase SRCAP 1 0 SGPPS(0.967)PPS(0.028)TATS(0.004)FGGPRPR;SGPPS(0.57)PPS(0.425)T(0.004)ATSFGGPRPR;S(0.005)GPPS(0.995)PPSTATSFGGPRPR ;; 123.43 8.16E-05 63848000 3709.76 3289.41 3756.74 3823.37 3718.21 4461.96 3392.54 2892.3 4315.34 4182.09 TRUE FALSE FALSE 3416.128581 3573.731943 3895.968089 3807.549908 3673.872774 3536.499199 3487.725542 3774.148955 3841.957998 4327.417316 0.789415102 0.82583483 0.900298678 0.879866588 0.848975845 0.817230912 0.805960065 0.872148138 0.887817772 1 12.07929054 -9.404002059 1.074001474 1.00206459 0.838885133 0.343724741 0.046877699 0.219735407 0.444219381 0.02755294 0.006658018 3.94E-10 9.404002059 -0.163179458 SGPS(ph)PLSS(ph)PNGK ddPTM_HeLa_Curcumin_4h_R1 2 SGPSPLSSPNGK 12 0 H0YM23;O75179-6;O75179-7;O75179-2;O75179;O75179-4 H0YM23 ANKRD17 Ankyrin repeat domain-containing protein 17 2 0 S(0.015)GPS(0.984)PLS(0.361)S(0.639)PNGK;S(0.012)GPS(0.988)PLS(0.118)S(0.882)PNGK ; 136.27 0.0039698 215261000 19690.8 15860.6 17309.1 17374.5 17720.8 15740.9 11378.7 9924 17643.9 15258.8 TRUE FALSE FALSE 18132.2524 17231.51959 17950.59047 17302.60892 17509.49103 12476.0599 11697.9557 12949.78192 15708.40831 15789.04216 1.148407371 1.0913594 1.136901801 1.095861848 1.10896474 0.790172056 0.740890776 0.82017527 0.99489305 1 13.94663603 -5.25689826 23.51787484 1.082590756 0.779460445 0.878027026 0.050992444 47.66603581 246852.7932 0.008697377 0.021341457 5.53E-06 5.25689826 -0.303130311 SGQGFHGNSEVNAILS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 SGQGFHGNSEVNAILSPR 18 0 C9JW01;A0A0A0MR59;Q8TB72-2;Q8TB72-4;Q8TB72-3;Q8TB72 C9JW01 PUM2 Pumilio homolog 2 1 0 SGQGFHGNS(0.001)EVNAILS(0.999)PR;SGQGFHGNSEVNAILS(1)PR;SGQGFHGNSEVNAILS(1)PR ;; 148.33 6.51E-05 31746400 4229.54 3754.13 3319.98 2743.81 5350.1 6617.1 3693.87 3402.44 5880.8 3712.47 TRUE FALSE FALSE 3894.767446 4078.620269 3443.021379 2732.456841 5286.303552 5244.63887 3797.510051 4439.828293 5235.690953 3841.478056 1.013872106 1.061732023 0.896275165 0.711303514 1.37611187 1.365265867 0.988554404 1.15576042 1.362936577 1 11.9074458 -5.743224225 24.99990585 0.983659066 1.215064079 0.239701602 0.183374199 198.7934238 272838.2045 0.020507755 0.040952032 1.81E-06 5.743224225 0.231405013 SGRS(ph)PTGNTPPVIDSVSEK ddPTM_HeLa_Curcumin_4h_R1 2 SGRSPTGNTPPVIDSVSEK 19 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 S(0.056)GRS(0.928)PT(0.005)GNT(0.011)PPVIDSVSEK;S(0.001)GRS(0.993)PT(0.006)GNTPPVIDSVSEK ; 188.9 7.71E-09 24075000 3679.7 2974 2985.7 3215.9 2747.8 3312.7 2382.3 2511.4 3563.8 3243.8 TRUE FALSE FALSE 3388.447862 3231.059308 3096.352668 3202.593458 2715.03428 2625.608678 2449.140926 3277.114299 3172.860056 3356.521809 1.009511648 0.962621277 0.92248847 0.954140518 0.808883253 0.782240911 0.729666323 0.976342323 0.945282122 1 11.7127513 -6.129627404 1.194389432 1.002105432 0.813223884 0.48141283 0.067393346 0.213028388 0.599728399 0.010246563 0.021975237 7.42E-07 6.129627404 -0.188881548 SGS(ph)ESEEAELSLSLAR ddPTM_HeLa_Curcumin_4h_R1 1 SGSESEEAELSLSLAR 16 0 Q8IV50 Q8IV50 LYSMD2 LysM and putative peptidoglycan-binding domain-containing protein 2 1 0 S(0.008)GS(0.992)ESEEAELSLSLAR 136.63 0.00041944 6493600 1404.6 1041 1001.6 1194.2 1439 1832 1360 1412.6 1616.6 1144.8 TRUE FALSE FALSE 1293.424428 1130.979401 1038.720177 1189.258717 1421.840865 1452.022549 1398.15794 1843.295237 1439.263025 1184.581715 1.091882824 0.954750008 0.876866631 1.003948231 1.200289391 1.22576816 1.180296743 1.556072675 1.214996827 1 10.21016201 -1 0.591070194 1.024647362 31.67947182 0.689688199 0.101871728 54.21980098 0.398135257 0.016134646 2147.702425 0.1 1 30.65482446 SAPTAPT(ph)PPPPPPPATPR ddPTM_HeLa_Curcumin_4h_R1 1 SAPTAPTPPPPPPPATPR 18 0 A6NHN7;A6NHB5;Q14202-2;Q14202 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 0 SAPT(0.124)APT(0.876)PPPPPPPATPR 137.32 0.00085604 4557500 1127 998.65 1125.9 1488.5 1061 1218.6 894.78 293.01 1432.2 1269.5 TRUE FALSE FALSE 1037.796761 1084.968856 1167.626844 1482.340981 1048.348268 965.8486235 919.8851186 382.3474001 1275.091243 1313.615031 0.790031125 0.825941262 0.88886532 1.128443986 0.798063545 0.735260028 0.70026994 0.291065031 0.970673457 1 10.35932682 -4.211584241 1.122585318 0.902487191 1.53E-13 0.770701359 0.102386443 0.747669716 0.700451285 0.017357686 0.81496649 6.14E-05 4.211584241 -0.902487191 down SS(ph)DGS(ph)LSHEEDLAK ddPTM_HeLa_Curcumin_4h_R1 1 SSDGSLSHEEDLAK 14 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YEF9;E9PJZ7 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 2 0 S(0.417)S(0.583)DGS(0.857)LS(0.143)HEEDLAK 98.676 0.014047 37423000 7345.7 5748 5645.9 5633.5 6429.2 7291.3 4953.1 1527.4 7623.4 6400.3 TRUE FALSE FALSE 6764.280094 6244.831507 5855.142021 5610.19007 6352.535989 5779.00219 5092.070655 1993.097229 6787.132093 6622.709949 1.021376468 0.942942022 0.884100627 0.847113963 0.959204923 0.872603849 0.768880216 0.300948893 1.024827019 1 12.69320596 -4.209777491 1.318813587 0.980630408 1.30E-28 0.909479231 0.061012147 0.34212469 0.465961134 0.010320496 0.463223434 6.17E-05 4.209777491 -0.980630408 down SGS(ph)ISVK ddPTM_HeLa_Curcumin_4h_R1 1 SGSISVK 7 0 Q8TF01 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 0 S(0.001)GS(0.994)IS(0.006)VK 140.83 0.0020513 11569000 3621.7 3863.7 3389.2 3627.9 3290.9 5000.3 4021.5 4699 3404.6 4973.9 TRUE FALSE FALSE 3335.038623 4197.661012 3514.806733 3612.888711 3251.658167 3963.181415 4134.332467 6131.703468 3031.123898 5146.742655 0.647990165 0.815595668 0.682918686 0.701975784 0.631789539 0.770036833 0.80329108 1.191375571 0.588940248 1 12.32944393 -4.261675744 5.858799693 0.790971558 1.203100088 0.51442248 0.122854996 0.109400442 16.8879159 0.020647535 0.179057239 5.47E-05 4.261675744 0.41212853 ESDLPAADPS(ph)TPIPLKYEDESSR ddPTM_HeLa_Curcumin_4h_R1 1 ESDLPAADPSTPIPLKYEDESSR 23 1 H0Y353;Q3B7T1-3;Q3B7T1-5;Q3B7T1 H0Y353 EDRF1 Erythroid differentiation-related factor 1 1 0 ES(0.004)DLPAADPS(0.491)T(0.491)PIPLKY(0.013)EDESSR 46.368 0.017589 3074900 752.97 747.3 791.5 876.84 648.71 1419.8 1431.6 2725.4 712.69 900.11 TRUE FALSE FALSE 693.37163 811.8932821 820.8336863 873.2118684 640.9745569 1125.317476 1471.766843 3556.361914 634.5096901 931.3887555 0.744449217 0.871701829 0.881300833 0.937537482 0.688192286 1.208214582 1.580185325 3.818343192 0.681251181 1 9.863239655 -4.027921331 1.484974074 0.872068247 6.522034176 0.979019766 0.129879156 0.193399916 0.249087334 0.018624131 1.888493684 9.38E-05 4.027921331 5.649965929 up SGS(ph)LLQVEETEREEGLGAGR ddPTM_HeLa_Curcumin_4h_R1 3 SGSLLQVEETEREEGLGAGR 20 1 Q8WYL5-2;Q8WYL5-5;Q8WYL5-4;Q8WYL5 Q8WYL5-2 SSH1 Protein phosphatase Slingshot homolog 1 1 0 S(0.223)GS(0.777)LLQVEETEREEGLGAGR;S(0.221)GS(0.779)LLQVEETEREEGLGAGR;S(0.24)GS(0.76)LLQVEETEREEGLGAGR ;; 93.196 0.0004164 30182700 3146.68 2059.49 2829.81 2672.7 3265.35 4270.92 3197.68 2969.47 3136.28 2896.23 TRUE FALSE FALSE 2897.616958 2237.503139 2934.685248 2661.641076 3226.412834 3385.083049 3287.398295 3874.847733 2792.237931 2996.873777 0.96687988 0.746612405 0.979248866 0.888139199 1.076592834 1.129538079 1.096942527 1.292963275 0.931716895 1 11.54924261 -4.807524693 0.982836472 0.95936563 1.287223601 0.641211527 0.084625166 0.544782875 0.674135398 0.013767413 0.153688375 1.56E-05 4.807524693 0.327857971 SGS(ph)MDPSGAHPSVR ddPTM_HeLa_Curcumin_4h_R1 4 SGSMDPSGAHPSVR 14 0 Q07666-2;Q07666;Q07666-3 Q07666-2 KHDRBS1 "KH domain-containing, RNA-binding, signal transduction-associated protein 1" 1 0 S(0.21)GS(0.79)MDPSGAHPSVR;S(0.02)GS(0.98)MDPSGAHPSVR;S(0.43)GS(0.57)MDPSGAHPSVR;S(0.011)GS(0.989)MDPSGAHPSVR ;;; 118.08 0.0019494 69720000 10022.3 9379.2 7872.88 7891.9 12548.3 23438.4 9944.44 4274.94 13448.6 9080.2 TRUE FALSE FALSE 9229.02438 10189.89626 8164.655858 7859.245409 12398.66972 18577.01163 10223.45422 5578.349527 11973.32223 9395.736274 0.982256644 1.084523443 0.868974567 0.836469349 1.319605974 1.977174656 1.08809506 0.593710739 1.274335707 1 13.1977905 -5.748475791 24.90335736 0.979250409 1.285787866 0.098314475 0.335910281 307.1450275 590028.8687 0.046561703 0.092651857 1.78E-06 5.748475791 0.306537457 SGS(ph)NGSVVSLEQQQK ddPTM_HeLa_Curcumin_4h_R1 1 SGSNGSVVSLEQQQK 15 0 Q2M1P5 Q2M1P5 KIF7 Kinesin-like protein KIF7 1 0 S(0.007)GS(0.993)NGSVVSLEQQQK 173.19 0.00012758 10756000 1729.1 1208.2 1513.8 1433.5 1590.3 2166.4 1199 1039.8 1838.1 1495.6 TRUE FALSE FALSE 1592.23991 1312.631424 1569.90276 1427.568557 1571.336711 1717.06422 1232.640713 1356.830233 1636.465029 1547.571989 1.028863227 0.848187635 1.014429552 0.922456963 1.015356134 1.109521387 0.796499757 0.876747733 1.057440326 1 10.59579081 -4.746009201 24.99999579 1.000889707 0.836623679 0.464864641 0.06990298 148.5069457 240607.0448 0.009036343 0.033561606 1.79E-05 4.746009201 -0.164266028 SGS(ph)PAPETTNESVPFAQHSSLDSR ddPTM_HeLa_Curcumin_4h_R1 1 SGSPAPETTNESVPFAQHSSLDSR 24 0 O15047 O15047 SETD1A Histone-lysine N-methyltransferase SETD1A 1 0 S(0.208)GS(0.792)PAPETTNESVPFAQHSSLDSR 148.84 3.75E-07 12502000 1736.8 1423 1716.1 1596.5 1626.5 2492.1 1535.2 1246 1712.5 1211.8 TRUE FALSE FALSE 1599.330447 1545.997779 1779.700176 1589.894106 1607.10505 1975.210368 1578.27358 1625.899664 1524.643034 1253.90996 1.275474714 1.232941622 1.419320551 1.267949181 1.281675002 1.575240991 1.258681748 1.296663809 1.215911097 1 10.29221804 -9.002564808 0.389773455 0.914698945 1.361947017 0.321789919 0.11415488 0.936559611 0.217302862 0.175182015 0.035378157 9.94E-10 9.002564808 0.447248073 SGS(ph)PISSEER ddPTM_HeLa_Curcumin_4h_R1 2 SGSPISSEER 10 0 H8Y6P7;P0CAP2-3;P0CAP2;P0CAP1-11;P0CAP2-2 H8Y6P7 GCOM1;POLR2M DNA-directed RNA polymerase II subunit GRINL1A 1 0 S(0.418)GS(0.581)PIS(0.002)SEER;S(0.014)GS(0.985)PISSEER ; 132.03 0.0026329 173585000 4532.2 3891.3 3878.8 3918 4051.3 4579.9 3476.2 2077.77 4509.5 3609.1 TRUE FALSE FALSE 4173.471588 4227.646633 4022.55174 3901.788354 4002.990893 3629.977114 3573.732816 2711.272508 4014.819132 3734.515956 1.117540168 1.132046745 1.07712801 1.044790918 1.071890157 0.972007392 0.956946726 0.726003728 1.075057432 1 11.86670555 -3.635512465 0.927105243 1.064813677 1.24E-16 0.877903861 0.039021724 1.867276135 0.535688028 0.008141216 2.649602366 0.000231466 3.635512465 -1.064813677 SGS(ph)PISSEERR ddPTM_HeLa_Curcumin_4h_R1 4 SGSPISSEERR 11 1 H8Y6P7;P0CAP2-3;P0CAP2;P0CAP1-11;P0CAP2-2 H8Y6P7 GCOM1;POLR2M DNA-directed RNA polymerase II subunit GRINL1A 1 0 S(0.027)GS(0.973)PISSEERR;S(0.177)GS(0.823)PISSEERR;S(0.011)GS(0.989)PISSEERR;S(0.152)GS(0.848)PISSEERR ;;; 102.33 0.0045308 50964000 7223 7030.36 5895.89 6604.6 6438.8 7577.7 6167.41 4112.48 6855.97 6783.79 TRUE FALSE FALSE 6651.291928 7638.032992 6114.39687 6577.271915 6362.021515 6005.999602 6340.450926 5366.35622 6103.887244 7019.526198 0.947541435 1.088112328 0.871055495 0.936996562 0.906332042 0.855613247 0.903259101 0.764489806 0.869558297 1 12.77715794 -1.87994984 0.291849621 0.990028657 5.90E-10 0.392324287 0.064809309 15.09631753 0.307326009 0.020653747 7.097737517 0.01318409 1.87994984 -0.990028657 SGS(ph)S(ph)PGLRDGSGT(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 SGSSPGLRDGSGTPSR 16 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 3 0 S(0.141)GS(0.867)S(0.981)PGLRDGS(0.283)GT(0.483)PS(0.246)R 92.671 0.0077038 12315000 2991.9 2128.2 2065.9 2468.8 1779.5 2718.9 2258.7 1793.1 2856.3 2415.4 TRUE FALSE FALSE 2755.087958 2312.152125 2142.464071 2458.58476 1758.280625 2154.969492 2322.073043 2339.807936 2542.971036 2499.33497 1.102328416 0.925106939 0.857213658 0.983695579 0.703499389 0.862217157 0.929076363 0.936172207 1.017459071 1 11.28732855 -7.094545413 4.638565834 1.04797257 0.877792831 0.485746169 0.07395644 0.136268611 4.950771536 0.012963504 0.016059357 8.04E-08 7.094545413 -0.17017974 SGS(ph)SPGLR ddPTM_HeLa_Curcumin_4h_R1 2 SGSSPGLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.008)GS(0.668)S(0.324)PGLR;S(0.02)GS(0.49)S(0.49)PGLR ; 134.77 0.0042283 395798000 7889.4 9407.1 7768.1 6441.8 7009.9 6564.7 4310.9 3145.8 5884.6 6747.8 TRUE FALSE FALSE 7264.945665 10220.20781 8055.99262 6415.145538 6926.311521 5203.107221 4431.852252 4104.939939 5239.074103 6982.285548 1.040482463 1.463733864 1.153775875 0.918774446 0.991983423 0.745186828 0.634728016 0.587907772 0.75033799 1 12.76948364 -5.171482061 1.414448998 1.063783089 0.58338393 0.539933673 0.169794384 0.241418066 0.872454325 0.022938411 0.100136954 6.74E-06 5.171482061 -0.480399159 SGS(ph)SQELDVKPSASPQER ddPTM_HeLa_Curcumin_4h_R1 1 SGSSQELDVKPSASPQER 18 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.2)GS(0.773)S(0.026)QELDVKPSASPQER 131.09 0.0022496 17706000 507 626.36 539.92 653.93 563.65 642.15 528.83 280.74 696.07 539.14 TRUE FALSE FALSE 466.870415 680.4997674 559.9299102 651.2242109 556.9288419 508.9608515 543.6675465 366.3363336 619.7128625 557.8750749 0.836872691 1.219806724 1.003683325 1.16732982 0.998303862 0.912320472 0.974532778 0.656663741 1.110845224 1 9.123798285 -4.26088643 23.27710834 0.969884732 0.656663528 0.395032471 0.12049888 15.05337617 633215.2553 0.017392243 0.137852702 5.48E-05 4.26088643 -0.313221204 SGS(ph)SS(ph)PDSEITELK ddPTM_HeLa_Curcumin_4h_R1 1 SGSSSPDSEITELK 14 0 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 2 0 S(0.001)GS(0.695)S(0.353)S(0.778)PDS(0.128)EIT(0.045)ELK 145.61 0.0014908 15776000 4569.9 4512 4948.4 4723.6 5048.4 5021.7 5113.3 4276.3 4154 4409 TRUE FALSE FALSE 4208.187593 4901.997175 5131.792057 4704.054995 4988.201127 3980.142814 5256.765436 5580.124184 3698.316593 4562.212422 0.922400626 1.074478065 1.124847241 1.031090743 1.093373273 0.872415058 1.152240394 1.223118011 0.810641034 1 12.15551791 -7.246330185 22.98146957 0.963355854 1.076486754 0.345486678 0.099957623 283.4374955 431115.041 0.014829401 0.018112848 5.67E-08 7.246330185 0.1131309 TQTPPVS(ph)PAPQPT(ph)EERLPSSPVYEDAASFK ddPTM_HeLa_Curcumin_4h_R1 1 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 2 0 T(0.027)QT(0.034)PPVS(0.632)PAPQPT(0.553)EERLPS(0.338)S(0.335)PVY(0.066)EDAAS(0.014)FK 51.104 0.017224 75966000 1975.4 1551.4 1697.3 1540.8 1676.6 2639.1 2240.8 3042.7 2169.5 1792 TRUE FALSE FALSE 1819.045006 1685.496103 1760.203431 1534.424578 1656.60764 2091.720911 2303.670817 3970.405223 1931.511278 1854.271867 0.981002321 0.908980033 0.94926934 0.827507878 0.893400623 1.128055141 1.242358717 2.141220656 1.041654847 1 10.85663707 -4.016134756 1.463208785 0.965483585 3.262752434 0.961384256 0.071059492 0.286942055 0.350051685 0.010579744 1.133697928 9.64E-05 4.016134756 2.29726885 up SGSAS(ph)PAPGDTLPWNLPK ddPTM_HeLa_Curcumin_4h_R1 1 SGSASPAPGDTLPWNLPK 18 0 F6QMI7;E7ETB9;Q5T0V7;Q03001-11 F6QMI7 DST Dystonin 1 0 S(0.001)GS(0.034)AS(0.964)PAPGDT(0.001)LPWNLPK 124.68 0.00025966 27826000 2489.4 2081.5 1804.5 2122.6 1891.9 2559.9 2220.8 1572.9 2614.9 2041.4 TRUE FALSE FALSE 2292.361363 2261.415585 1871.376357 2113.817244 1869.340328 2028.947884 2283.109671 2052.469969 2328.052012 2112.338498 1.08522444 1.070574431 0.88592636 1.000700051 0.884962486 0.960522135 1.080844606 0.971657701 1.102120713 1 11.04462533 -6.792502013 24.99871998 1.043644086 0.967312154 0.388353733 0.059374231 202.0641666 162617.3328 0.009920158 0.01303838 1.61E-07 6.792502013 -0.076331932 SGSGSVGNGSSRYSPS(ph)QNS(ph)PIHHIPSRR ddPTM_HeLa_Curcumin_4h_R1 1 SGSGSVGNGSSRYSPSQNSPIHHIPSRR 28 2 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 0 S(0.001)GS(0.005)GS(0.005)VGNGS(0.025)S(0.025)RY(0.056)S(0.134)PS(0.74)QNS(0.809)PIHHIPS(0.201)RR 42.557 0.017113 12412000 1066.8 1028.1 968.97 982.22 1064.6 1321.5 932.86 660.08 1309.2 1114.9 TRUE FALSE FALSE 982.3616543 1116.964383 1004.880881 978.1558339 1051.90534 1047.406004 959.0335409 861.3353534 1165.584035 1153.642692 0.851530254 0.968206526 0.871050359 0.847884567 0.911812078 0.907911965 0.83130899 0.746622294 1.01035099 1 10.17198074 -13.52287875 0.161997363 1.505410142 0.825202731 0.577792247 0.050704893 40.67155592 0.437760006 6.582899281 0.100492084 3.00E-14 13.52287875 -0.68020741 SGSGTMNLGGSLTR ddPTM_HeLa_Curcumin_4h_R1 1 SGSGTMNLGGSLTR 14 0 B1AK87;P47756-2;P47756;B1AK88;B1AK85 B1AK87 CAPZB F-actin-capping protein subunit beta 0 0 126.5 0.0017416 3218900 404.02 336.26 268.17 414.31 332.2 503.15 461.71 309.95 624.04 450.71 FALSE FALSE TRUE 372.0413907 365.3248161 278.1086161 412.595695 328.238732 398.7910183 474.66434 404.4523282 555.5843733 466.372139 0.797735027 0.783333277 0.596323393 0.884691989 0.703812909 0.855091857 1.017780224 0.867230896 1.191289802 1 8.865337794 -9.133379111 0.939526874 0.997603962 0.812825828 0.404531537 0.123866593 0.568621612 0.921689368 0.068641693 0.02094409 7.36E-10 9.133379111 -0.184778135 SGSIGAADS(ph)PENWEK ddPTM_HeLa_Curcumin_4h_R1 1 SGSIGAADSPENWEK 15 0 D6RAI0;D6RGK7;D6RAZ3;D6R9T3;E7EMP6;Q96FZ2 D6RAI0 HMCES Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein 1 0 SGSIGAADS(1)PENWEK 100.43 0.0046173 0 956.23 837.75 758.41 870.73 739.21 941.07 841.29 946.64 1025.6 719.97 TRUE FALSE FALSE 880.5433865 910.1613771 786.5173418 867.12715 730.3954035 745.881474 864.8943332 1235.266178 913.0942459 744.9889039 1.181955036 1.22171132 1.0557437 1.163946396 0.980411117 1.001198098 1.160949282 1.658100103 1.225648115 1 9.541075128 -4.270556412 3.793813993 1.088390791 1.710944111 0.77306428 0.08917469 0.085949529 2.384988814 0.012828814 0.146922838 5.36E-05 4.270556412 0.622553321 LNRSDSDS(ph)STLAK ddPTM_HeLa_Curcumin_4h_R1 1 LNRSDSDSSTLAK 13 1 Q6AWC2-7;Q6AWC2-3;Q6AWC2-2;Q6AWC2-4;Q6AWC2;Q6AWC2-6 Q6AWC2-7 WWC2 Protein WWC2 1 0 LNRSDS(0.008)DS(0.49)S(0.49)T(0.012)LAK 150.26 0.0051722 6359200 3319.2 2220.9 2748.2 3029.8 2129.3 2876.8 1891.2 922.58 3154.4 3099.8 TRUE FALSE FALSE 3056.481818 2412.8647 2850.05071 3017.26349 2103.909488 2280.119252 1944.261982 1203.870395 2808.370212 3207.517819 0.952911874 0.752252937 0.888553352 0.940684872 0.655930725 0.710867213 0.606157812 0.375327734 0.875558725 1 11.64724156 -4.207745692 0.374976459 0.989890781 6.37E-14 0.788413655 0.084789911 1.591259516 0.149248554 0.022795475 0.714645453 6.20E-05 4.207745692 -0.989890781 down SGSLDDS(ph)FSDFQELPASSK ddPTM_HeLa_Curcumin_4h_R1 3 SGSLDDSFSDFQELPASSK 19 0 Q9UMZ2-6;Q9UMZ2-9;Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2 Q9UMZ2-6 SYNRG Synergin gamma 1 0 SGSLDDS(0.503)FS(0.496)DFQELPASSK;SGS(0.001)LDDS(0.999)FSDFQELPASSK;SGS(0.001)LDDS(0.765)FS(0.234)DFQELPASSK ;; 302.84 2.51E-98 38449300 15353.4 12703.6 14264.9 14393.6 14086.5 16146.6 12200.2 10968.6 15077.6 14426.3 TRUE FALSE FALSE 14138.16219 13801.64258 14793.56974 14334.0431 13918.52769 12797.61315 12542.50478 14312.87565 13423.625 14927.61285 0.947114742 0.924571311 0.991020459 0.960236793 0.932401438 0.857311432 0.840221736 0.958818787 0.899247933 1 13.86569585 -5.534569782 3.04241337 0.970645541 0.881416287 0.29724108 0.041893482 0.150145312 2.83831736 0.005461567 0.012398258 2.92E-06 5.534569782 -0.089229254 SGSLDSELS(ph)VSPK ddPTM_HeLa_Curcumin_4h_R1 1 SGSLDSELSVSPK 13 0 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 S(0.006)GS(0.001)LDS(0.042)ELS(0.913)VS(0.037)PK 195.71 3.92E-06 239220000 6547.9 5929.8 6590.7 5851.6 6356.3 6913 4640.6 3009.1 6913.7 5235.4 TRUE FALSE FALSE 6029.626806 6442.345489 6834.95714 5827.38763 6280.505274 5479.165874 4770.802746 3926.560738 6155.284407 5417.32976 1.113025618 1.18921051 1.261683789 1.075693725 1.159335974 1.011414501 0.880655776 0.724814791 1.136221105 1 12.4033662 -4.597862918 1.869778908 1.088875785 0.713026418 0.745642365 0.07587763 0.225454708 1.260229102 0.013212744 0.116806523 2.52E-05 4.597862918 -0.375849367 SGSLDSELSVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SGSLDSELSVSPK 13 0 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 SGSLDSELS(0.017)VS(0.983)PK;SGSLDSELS(0.047)VS(0.953)PK ; 180.84 0.00013904 117194000 6787.9 5440 6592.2 6595.5 6267.9 6362.3 4791.4 3580.9 6789.7 5913 TRUE FALSE FALSE 6250.630552 5910.20936 6836.512731 6568.209569 6193.159386 5042.687262 4925.833789 4672.699926 6044.886897 6118.47631 1.021599208 0.965960978 1.11735543 1.073504127 1.012206156 0.824173701 0.805075241 0.763703198 0.987972592 1 12.57895671 -5.222800079 3.732103379 1.020818195 0.790950912 0.861577246 0.04200793 0.063022201 1.868417779 0.006192006 0.016432422 5.99E-06 5.222800079 -0.229867282 SGSLDSELSVS(ph)PKR ddPTM_HeLa_Curcumin_4h_R1 1 SGSLDSELSVSPKR 14 1 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 SGSLDSELSVS(1)PKR 164.15 1.51E-10 0 2220.5 1859.4 1620.7 2022.3 1500.5 1899.7 1127.3 852.06 2235.4 1860.6 TRUE FALSE FALSE 2044.745082 2020.118251 1680.764568 2013.932258 1482.607518 1505.680806 1158.929004 1111.849172 1990.182213 1925.255712 1.062064156 1.049272696 0.873008483 1.04605962 0.770083428 0.78206796 0.601961078 0.577507271 1.033723573 1 10.91083436 -5.190444232 0.797440614 1.029516564 0.517048566 0.875091736 0.063017945 0.218275021 0.19989129 0.010174832 0.074968694 6.45E-06 5.190444232 -0.512467999 SGSMEEDVDTS(ph)PGGDYYTSPS(ph)SPTSSSR ddPTM_HeLa_Curcumin_4h_R1 1 SGSMEEDVDTSPGGDYYTSPSSPTSSSR 28 0 A0A286YEX4;P08651-4;P08651-5;P08651-3;P08651-6;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 2 0 SGSMEEDVDT(0.163)S(0.837)PGGDYYTS(0.001)PS(0.476)S(0.397)PT(0.092)S(0.026)S(0.008)SR 127.59 6.46E-10 9319200 4533.1 4182.3 3941.8 4355.3 4703.4 5064.9 3987.5 2387 5056.6 4311.8 TRUE FALSE FALSE 4174.300352 4543.799376 4087.886576 4337.278923 4647.315027 4014.382647 4099.378518 3114.785312 4501.903631 4461.634729 0.935598857 1.018415817 0.91623067 0.972127748 1.0416171 0.899756007 0.918806394 0.698126472 1.009025594 1 12.12335669 -3.747500939 1.24655987 0.971903952 0.13153412 0.797481906 0.041979492 1.432093161 0.77129128 0.005993636 2.116091407 0.000178854 3.747500939 -0.840369832 SGSMEEDVDTS(ph)PGGDYYTSPSS(ph)PTSSSR ddPTM_HeLa_Curcumin_4h_R1 2 SGSMEEDVDTSPGGDYYTSPSSPTSSSR 28 0 A0A286YEX4;P08651-4;P08651-5;P08651-3;P08651-6;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 2 0 SGSMEEDVDT(0.091)S(0.909)PGGDYYTS(0.002)PS(0.452)S(0.513)PT(0.024)S(0.007)S(0.002)SR;SGSMEEDVDT(0.09)S(0.907)PGGDYY(0.002)T(0.014)S(0.073)PS(0.256)S(0.579)PT(0.053)S(0.018)S(0.006)S(0.002)R ; 175.67 7.56E-15 17779600 5433.5 4300.4 4574.4 4473.7 4644.4 5643.7 4449.8 2236.26 4855 4590.6 TRUE FALSE FALSE 5003.432742 4672.107414 4743.931288 4455.189015 4589.018563 4473.133002 4574.649412 2918.08538 4322.418647 4750.123008 1.053326984 0.98357609 0.998696514 0.937910241 0.966084153 0.941687825 0.963059147 0.614317855 0.909959308 1 12.21374916 -3.853315841 1.408860471 1.008717005 9.75E-26 0.814321002 0.049107901 0.851282258 0.691225191 0.006469667 1.607216373 0.000140179 3.853315841 -1.008717005 SGSMEEDVDTSPGGDYYTSPS(ph)SPTSSSR ddPTM_HeLa_Curcumin_4h_R1 2 SGSMEEDVDTSPGGDYYTSPSSPTSSSR 28 0 A0A286YEX4;P08651-4;P08651-5;P08651-3;P08651-6;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 0 SGSMEEDVDTSPGGDYYTSPS(0.577)S(0.327)PT(0.065)S(0.023)S(0.008)SR;SGSMEEDVDTSPGGDYYTSPS(0.596)S(0.319)PT(0.058)S(0.019)S(0.007)S(0.001)R ; 221.37 3.92E-31 32636000 11284.9 9164.9 10449.6 9919 10993.1 13821.2 10634.4 7491 11329.6 9400.3 TRUE FALSE FALSE 10391.68826 9957.073118 10836.87137 9877.957806 10862.01446 10954.52732 10932.77264 9774.971416 10086.77123 9726.959725 1.068338777 1.023657278 1.114106738 1.015523667 1.116691625 1.126202599 1.123966065 1.00493594 1.036991158 1 13.24777323 -9.490800537 0.272163199 0.953325123 1.092580469 0.19372948 0.044944164 4.661674837 0.422841865 0.213719419 0.030630515 3.23E-10 9.490800537 0.139255347 SGSMEEDVDTSPGGDYYTSPSS(ph)PTSSSR ddPTM_HeLa_Curcumin_4h_R1 2 SGSMEEDVDTSPGGDYYTSPSSPTSSSR 28 0 A0A286YEX4;P08651-4;P08651-5;P08651-3;P08651-6;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 0 SGSMEEDVDTSPGGDYYTSPS(0.284)S(0.538)PT(0.12)S(0.042)S(0.015)S(0.001)R;SGSMEEDVDTSPGGDYYTSPS(0.015)S(0.791)PT(0.135)S(0.044)S(0.015)SR ; 229.77 8.42E-38 21527900 4165.3 3525.4 3656.9 3783.3 4183.3 5356.6 3800.4 3331 4362 3838.4 TRUE FALSE FALSE 3835.61211 3830.119867 3792.427931 3767.645707 4133.41688 4245.580779 3907.028996 4346.606566 3883.499513 3971.784114 0.965715155 0.96433234 0.954842414 0.948602844 1.040695255 1.068935435 0.983696214 1.094371305 0.977772054 1 11.95557149 -5.740955282 22.02888964 0.977195437 1.043980619 0.614618119 0.02990284 36.96312913 39749.46853 0.004364116 0.008714276 1.82E-06 5.740955282 0.066785183 SGSPSDNS(ph)GAEEMEVSLAKPK ddPTM_HeLa_Curcumin_4h_R1 2 SGSPSDNSGAEEMEVSLAKPK 21 1 P31749;P31749-2 P31749 AKT1 RAC-alpha serine/threonine-protein kinase 1 0 S(0.001)GS(0.025)PS(0.032)DNS(0.941)GAEEMEVSLAKPK;S(0.003)GS(0.089)PS(0.101)DNS(0.807)GAEEMEVSLAKPK ; 88.574 0.0013857 131001000 8166.2 6275.8 6660.7 7626.1 7108.4 8193.7 6370.4 7827.3 8090.5 7252.8 TRUE FALSE FALSE 7519.836653 6818.252188 6907.551401 7594.545219 7023.636973 6494.234258 6549.136279 10213.80774 7202.992391 7504.83426 1.001999031 0.908514692 0.920413584 1.011953756 0.93588169 0.86534013 0.872655685 1.360963798 0.959780342 1 12.8736045 -4.252504836 24.84883081 0.97037275 1.360964017 0.825769292 0.056401805 392.6444876 1092001.057 0.008959371 0.145193342 5.59E-05 4.252504836 0.390591267 SGSS(ph)PGLR ddPTM_HeLa_Curcumin_4h_R1 2 SGSSPGLR 8 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.005)GS(0.355)S(0.64)PGLR;S(0.015)GS(0.34)S(0.645)PGLR ; 114.89 0.0098653 370855000 8177.6 10481.3 8660.5 6951 7430.3 8179.8 4754.6 3638.3 7282.3 7729.8 TRUE FALSE FALSE 7530.334331 11387.25687 8981.465749 6922.238604 7341.698525 6483.217275 4888.00128 4747.600921 6483.449909 7998.409975 0.941478913 1.423690071 1.1229064 0.865451837 0.91789475 0.810563261 0.611121622 0.593568089 0.810592346 1 12.96549752 -5.04634592 1.192758177 1.016293591 0.557786914 0.53544306 0.156848883 0.364183412 0.849488764 0.02384287 0.144776711 8.99E-06 5.04634592 -0.458506677 SGSS(ph)PGLRDGSGTPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 SGSSPGLRDGSGTPSR 16 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(0.012)GS(0.294)S(0.694)PGLRDGS(0.003)GT(0.089)PS(0.908)R;S(0.022)GS(0.122)S(0.856)PGLRDGS(0.041)GT(0.361)PS(0.599)R ; 118.15 0.0042058 12114700 4908.4 3431.5 3014.3 4138.4 2791.2 4403.2 2463.7 1884.92 5767.3 4168.4 TRUE FALSE FALSE 4519.894961 3728.10357 3126.01261 4121.276397 2757.916763 3489.926686 2532.824791 2459.623431 5134.641619 4313.25159 1.047908954 0.864337146 0.724746179 0.95549177 0.639405494 0.809117348 0.587219349 0.570248078 1.190434064 1 12.07456015 -5.753586763 0.463509962 1.03359265 0.523664845 0.718878313 0.105601894 0.576924733 0.189656045 0.026047247 0.130911663 1.76E-06 5.753586763 -0.509927805 SGSS(ph)QELDVKPSAS(ph)PQER ddPTM_HeLa_Curcumin_4h_R1 1 SGSSQELDVKPSASPQER 18 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(0.025)GS(0.29)S(0.684)QELDVKPS(0.001)AS(0.999)PQER 236.6 5.36E-24 8858500 2615.2 2195.8 2220.9 2311.3 2375.7 3021.9 2847.6 2929.1 2304 1962.8 TRUE FALSE FALSE 2408.20416 2385.595168 2303.208508 2301.736453 2347.371329 2395.123876 2927.495992 3822.169106 2051.256964 2031.007154 1.185719191 1.17458728 1.134022843 1.133298053 1.15576714 1.179278897 1.441401123 1.881908244 1.009970329 1 10.98797961 -4.053503356 1.114710092 1.103270476 2.572537737 0.942630296 0.058800197 0.495130328 0.365129143 0.011474004 0.948480872 8.84E-05 4.053503356 1.469267261 SGSS(ph)S(ph)PDSEITELK ddPTM_HeLa_Curcumin_4h_R1 1 SGSSSPDSEITELK 14 0 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 2 0 S(0.012)GS(0.123)S(0.784)S(0.666)PDS(0.413)EIT(0.002)ELK 102.52 0.010031 16425000 7645.2 6736.9 7212.9 7875.8 9383.6 8255.9 7792 7791.3 7090.7 6309.2 TRUE FALSE FALSE 7040.074353 7319.207617 7480.216419 7843.212026 9271.706699 6543.533277 8010.622549 10166.8315 6312.86795 6528.44423 1.078369379 1.121125855 1.145788515 1.201390676 1.420201563 1.002311278 1.227033925 1.557313066 0.96697892 1 12.67252351 -1 0.191621704 0.983106249 2.909191209 0.53510733 0.1231863 32.2228232 0.36183851 0.128251866 18.52857351 0.1 1 1.92608496 SGSS(ph)SPDS(ph)EITELKFPSINHD ddPTM_HeLa_Curcumin_4h_R1 1 SGSSSPDSEITELKFPSINHD 21 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 2 0 S(0.329)GS(0.39)S(0.373)S(0.326)PDS(0.546)EIT(0.028)ELKFPS(0.009)INHD 63.701 0.0052506 26601000 1197.2 1205.2 795.02 649.28 1911.3 2718.4 1425.1 1403.2 1712.8 1199 TRUE FALSE FALSE 1102.440357 1309.372118 824.4841406 646.5934514 1888.508996 2154.573197 1465.084471 1831.02922 1524.910125 1240.665161 0.888588147 1.05537913 0.664550087 0.521166768 1.522174601 1.736627468 1.180886283 1.475844796 1.229106913 1 10.27689809 -5.737826959 24.99719663 0.904954234 1.476008372 0.622307435 0.22343728 111.1703248 117689.3912 0.029622169 0.059217632 1.83E-06 5.737826959 0.571054137 SGSS(ph)SPDSEITELK ddPTM_HeLa_Curcumin_4h_R1 1 SGSSSPDSEITELK 14 0 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 0 SGS(0.001)S(0.499)S(0.499)PDS(0.002)EITELK 300.49 1.16E-91 109400000 5117.2 4713.2 5279.3 5239.8 6297.1 6081.2 4920.8 6557.8 4311.6 4722.6 TRUE FALSE FALSE 4712.16822 5120.588006 5474.955502 5218.119096 6222.011195 4819.890571 5058.864404 8557.243032 3838.628267 4886.709998 0.964282354 1.047860014 1.120376594 1.06781845 1.273251574 0.986326296 1.035229102 1.751125611 0.785524058 1 12.25464778 -4.261556042 6.981009372 1.023716413 1.761981667 0.773655465 0.116776772 0.031911065 11.67695506 0.013585141 0.110697832 5.48E-05 4.261556042 0.738265254 SGSSS(ph)PDS(ph)EITELKFPSINHD ddPTM_HeLa_Curcumin_4h_R1 1 SGSSSPDSEITELKFPSINHD 21 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 2 0 S(0.008)GS(0.043)S(0.269)S(0.703)PDS(0.894)EIT(0.084)ELKFPS(0.001)INHD 91.589 0.00031218 35407000 1394.5 1059.7 1020.3 1116.1 1582.9 2500.7 1342.2 1249.8 1796 1106.1 TRUE FALSE FALSE 1284.123854 1151.295746 1058.113216 1111.481874 1564.024951 1982.026631 1379.85852 1630.858267 1598.983293 1144.536893 1.121959337 1.005905317 0.924490265 0.971119307 1.366513357 1.731728041 1.20560423 1.424906682 1.397057014 1 10.16054825 -5.680777737 5.325935206 1.038334032 1.446055397 0.512027243 0.172491591 0.089190962 4.332674918 0.018938833 0.038200621 2.09E-06 5.680777737 0.407721365 SGSSS(ph)PDSEITELK ddPTM_HeLa_Curcumin_4h_R1 2 SGSSSPDSEITELK 14 0 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 0 SGS(0.001)S(0.085)S(0.872)PDS(0.042)EITELK;SGS(0.002)S(0.021)S(0.956)PDS(0.021)EITELK ; 228.7 2.17E-20 251282000 8679.3 7310.9 8640.6 7947.9 10286.1 10202.2 8420.8 9617 7604.3 6150.2 TRUE FALSE FALSE 7992.324247 7942.821619 8960.828237 7915.013696 10163.44498 8086.148718 8657.064985 12549.17903 6770.127315 6363.918992 1.25588089 1.248102251 1.408067615 1.243732628 1.597041852 1.27062408 1.360335509 1.971926268 1.063829902 1 12.63569976 -1 0.12854176 0.894400527 3.463717537 0.627394527 0.160561144 39.7703615 0.34580052 0.546188145 18.55885325 0.1 1 2.56931701 SGSSS(ph)PDSEITELKFPSINHD ddPTM_HeLa_Curcumin_4h_R1 1 SGSSSPDSEITELKFPSINHD 21 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 0 S(0.014)GS(0.05)S(0.191)S(0.735)PDS(0.01)EITELKFPSINHD 126.3 6.84E-06 566550000 1736.1 1468.6 1118.4 1222.6 1939.2 3366.3 1737 2046.6 2350.1 1285.1 TRUE FALSE FALSE 1598.685853 1595.53924 1159.848888 1217.541205 1916.076307 2668.091434 1785.735545 2670.598919 2092.29991 1329.757129 1.202238979 1.199872672 0.87222611 0.915611715 1.440922003 2.006450182 1.342903532 2.008335853 1.573445153 1 10.37694706 -5.546310871 4.936009462 1.078053996 1.742123279 0.56656669 0.255492039 0.074117873 4.741082686 0.028125845 0.059034296 2.84E-06 5.546310871 0.664069282 SGSSSPDS(ph)EITELK ddPTM_HeLa_Curcumin_4h_R1 1 SGSSSPDSEITELK 14 0 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 0 SGS(0.011)S(0.059)S(0.342)PDS(0.551)EIT(0.038)ELK 83.862 0.015576 197850000 2332.1 2212.9 2558.3 2747.8 3201.5 3323.2 2392.2 3056.3 2462.7 2231.2 TRUE FALSE FALSE 2147.511824 2404.173216 2653.112849 2736.430332 3163.324203 2633.93086 2459.318694 3988.151801 2192.547971 2308.734034 0.930168565 1.041338318 1.149163485 1.185251437 1.370155313 1.140855041 1.06522391 1.727419331 0.949675423 1 11.17288627 -6.457972574 1.129778763 0.965403743 1.302143301 0.461581557 0.166164083 0.310029061 0.787970728 0.028006988 0.05056083 3.48E-07 6.457972574 0.336739558 SGSSSPDS(ph)EITELKFPSINHD ddPTM_HeLa_Curcumin_4h_R1 3 SGSSSPDSEITELKFPSINHD 21 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 1 0 S(0.019)GS(0.019)S(0.054)S(0.054)PDS(0.816)EIT(0.037)ELKFPSINHD;S(0.069)GS(0.069)S(0.252)S(0.252)PDS(0.341)EIT(0.015)ELKFPSINHD;S(0.015)GS(0.025)S(0.065)S(0.169)PDS(0.495)EIT(0.23)ELKFPS(0.002)INHD ;; 65.854 0.0019541 330050700 4317.14 4306.36 4109.88 4050.39 4694.43 5850.2 3410.37 4130.84 5464.4 5000.73 TRUE FALSE FALSE 3975.433814 4678.58257 4262.195768 4033.630559 4638.451988 4636.802575 3506.055804 5390.3141 4864.968991 5174.504995 0.768273258 0.904160412 0.823691497 0.779520082 0.896404969 0.896086211 0.677563517 1.041706232 0.940180558 1 12.33720514 -9.484983359 1.196281958 1.00102527 0.83658017 0.192952179 0.094855803 0.448313518 1.136444399 0.06123727 0.014579409 3.27E-10 9.484983359 -0.1644451 SGSYSGRS(ph)PS(ph)PY(ph)GR ddPTM_HeLa_Curcumin_4h_R1 1 SGSYSGRSPSPYGR 14 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 3 0 S(0.021)GS(0.121)Y(0.026)S(0.039)GRS(0.888)PS(0.979)PY(0.927)GR 83.243 0.0067914 27668000 4196.7 3382.4 3781.3 3963.9 3737.9 4961.1 3722.2 2572.4 4421 3912.9 TRUE FALSE FALSE 3864.526767 3674.759584 3921.438304 3947.498432 3693.327984 3932.111937 3826.634914 3356.712918 3936.027361 4048.872984 0.954469746 0.907600609 0.968525889 0.974962279 0.912186675 0.971162087 0.945111128 0.829048709 0.972129127 1 11.98330467 -5.181494374 0.012489594 1.854222536 1.15E-07 0.33467232 0.038158092 1851.270612 5.114335427 356.1948806 403.9530207 6.58E-06 5.181494374 -1.85422242 SGT(ph)FDLLEMDR ddPTM_HeLa_Curcumin_4h_R1 3 SGTFDLLEMDR 11 0 H0YA31;H0YA26;E9PHT6;Q9NVE7 H0YA31 PANK4 Pantothenate kinase 4 1 0 S(0.007)GT(0.993)FDLLEMDR;S(0.338)GT(0.662)FDLLEMDR;S(0.007)GT(0.993)FDLLEMDR ;; 201.38 1.07E-06 11592700 4186.81 6302.5 4157.91 3892.06 4705.77 9038.8 6664.3 3917.36 6199.3 5221.16 TRUE FALSE FALSE 3855.419571 6847.260017 4312.005802 3875.955687 4649.656766 7164.050992 6851.282322 5111.745031 5519.2523 5402.594921 0.713623662 1.267402076 0.798136056 0.71742482 0.860633979 1.326038894 1.268146589 0.946164779 1.021592842 1 12.3994368 -5.276033921 24.42568756 0.876134214 1.188919734 0.30125049 0.182077554 454.0335594 759878.6633 0.026673357 0.059902548 5.30E-06 5.276033921 0.31278552 SGT(ph)PPRQGS(ph)ITSPQANEQSVTPQR ddPTM_HeLa_Curcumin_4h_R1 1 SGTPPRQGSITSPQANEQSVTPQR 24 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(0.204)GT(0.797)PPRQGS(0.514)IT(0.399)S(0.086)PQANEQSVTPQR 77.657 0.00054733 21057000 1641.9 1233.6 1544.5 1618.4 1594.5 1734.5 1428.3 1747.4 1528.7 1047.1 TRUE FALSE FALSE 1511.941882 1340.226887 1601.740529 1611.70349 1575.486629 1374.745148 1468.374254 2280.174216 1361.005435 1083.486647 1.395441177 1.236957457 1.478320506 1.487515784 1.454089566 1.268815958 1.355230596 2.104478373 1.25613494 1 10.08146566 -1 0.044736338 1.33E-09 3.862123678 0.430495757 0.205203204 337.0363023 1.155581513 25.7702927 94.51516333 0.1 1 3.862123677 SGT(ph)PPRQGSIT(ph)SPQANEQSVTPQR ddPTM_HeLa_Curcumin_4h_R1 1 SGTPPRQGSITSPQANEQSVTPQR 24 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(0.228)GT(0.688)PPRQGS(0.299)IT(0.76)S(0.025)PQANEQSVTPQR 71.042 0.00057741 22531000 1291.9 1166.1 1070 1202 1335.4 1270.2 1102.4 1558.4 1092.4 1140.5 TRUE FALSE FALSE 1189.644752 1266.892488 1109.655141 1197.026442 1319.476227 1006.746202 1133.330377 2033.548986 972.5664531 1180.13229 1.008060505 1.073517349 0.940280298 1.014315473 1.118074845 0.853079108 0.960341808 1.723153415 0.824116467 1 10.20473288 -4.259512416 24.99976655 1.000386375 1.72315366 0.865021562 0.087999211 32.51962137 421865.7365 0.008750162 0.076121152 5.50E-05 4.259512416 0.722767285 SGT(ph)PPRQGSITSPQANEQSVTPQR ddPTM_HeLa_Curcumin_4h_R1 2 SGTPPRQGSITSPQANEQSVTPQR 24 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.326)GT(0.657)PPRQGS(0.015)IT(0.001)SPQANEQSVTPQR;S(0.213)GT(0.755)PPRQGS(0.032)ITSPQANEQSVTPQR ; 86.825 0.00010079 45164000 1415.07 1035.04 1361.62 1132.29 1275.13 1795.07 1430.2 1183.32 1488.38 1408.84 TRUE FALSE FALSE 1303.065716 1124.504246 1412.082835 1127.604884 1259.924908 1422.752247 1470.327563 1544.108821 1325.108438 1457.797085 0.893859461 0.771372269 0.968641555 0.773499203 0.86426631 0.975960414 1.008595488 1.059206961 0.90898003 1 10.50957421 -4.839451475 2.581191714 0.918207784 1.042721635 0.344298784 0.075324323 0.325117405 4.250772002 0.012379179 0.052437108 1.45E-05 4.839451475 0.124513851 SGT(ph)PTQDEMMDKPTSSSVDTMSLLSK ddPTM_HeLa_Curcumin_4h_R1 2 SGTPTQDEMMDKPTSSSVDTMSLLSK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 S(0.129)GT(0.753)PT(0.1)QDEMMDKPT(0.005)S(0.003)S(0.004)S(0.004)VDT(0.001)MSLLSK;S(0.085)GT(0.339)PT(0.062)QDEMMDKPT(0.165)S(0.208)S(0.076)S(0.046)VDT(0.014)MS(0.005)LLSK ; 84.962 5.19E-05 130249000 3763.6 2928.8 3612.3 3483.3 3440.4 3779.2 3113.8 2409.7 3691 3312.8 TRUE FALSE FALSE 3465.707089 3181.952422 3746.175016 3468.887028 3399.375477 2995.35132 3201.164848 3144.406437 3286.106534 3427.919553 1.01102346 0.928245944 1.092842162 1.011951119 0.991673061 0.873810273 0.933850634 0.917292949 0.958630004 1 11.74311754 -5.376500178 5.594723034 1.00641315 0.911333794 0.487730392 0.042388729 0.122301832 5.188695577 0.005320534 0.012067675 4.20E-06 5.376500178 -0.095079356 SGTAETEPVEQDS(ph)SQPSLPLVR ddPTM_HeLa_Curcumin_4h_R1 1 SGTAETEPVEQDSSQPSLPLVR 22 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0;H7C3N7 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 SGTAETEPVEQDS(0.5)S(0.5)QPSLPLVR 179.64 2.53E-10 14141000 3287.6 2267 2395.1 2496.5 2692.3 3161.3 2366.3 2279.5 2889 2146.6 TRUE FALSE FALSE 3027.382991 2462.949378 2483.864513 2486.170144 2660.196081 2505.610745 2432.692009 2974.509056 2572.083928 2221.19419 1.362952868 1.108840186 1.118256352 1.119294367 1.197642283 1.128046686 1.095218068 1.339148585 1.157973463 1 11.11711981 -9.690422304 1.576476252 1.000317029 1.203702401 0.042354033 0.103316863 0.364660786 1.637511318 0.076082463 0.0169874 2.04E-10 9.690422304 0.203385373 ESS(ph)PLPK ddPTM_HeLa_Curcumin_4h_R1 2 ESSPLPK 7 0 Q9HCE3 Q9HCE3 ZNF532 Zinc finger protein 532 1 0 ES(0.001)S(0.999)PLPK;ES(0.003)S(0.997)PLPK ; 121.09 0.011474 34283000 29012 26008.1 29093.4 26511.7 31246 29523.7 20780.1 7152 26866.5 22699.4 TRUE FALSE FALSE 26715.66959 28256.12427 30171.627 26402.00161 30873.41186 23400.15182 21363.13368 9332.611876 23919.31217 23488.20246 1.137408009 1.202992197 1.284543892 1.124053731 1.314422077 0.996251282 0.909526121 0.39733189 1.018354308 1 14.51964869 -4.206801493 1.690125882 1.111872606 0.081768973 0.82077573 0.104750779 0.393250808 0.969961446 0.017048074 0.682030447 6.21E-05 4.206801493 -1.030103634 down SGTAETEPVEQDSS(ph)QPSLPLVR ddPTM_HeLa_Curcumin_4h_R1 1 SGTAETEPVEQDSSQPSLPLVR 22 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0;H7C3N7 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 SGTAETEPVEQDS(0.391)S(0.609)QPSLPLVR 122.59 4.60E-06 14999000 2633.2 2423.5 1910.4 2411.6 2898.5 2997.6 1971.2 2139.5 2865.1 2032 TRUE FALSE FALSE 2424.779441 2632.976541 1981.201105 2401.621438 2863.937281 2375.86397 2026.506567 2791.823701 2550.805698 2102.611849 1.153222571 1.252240894 0.942257177 1.142208649 1.36208558 1.129958424 0.963804407 1.327788437 1.213160527 1 11.03796683 -9.290196435 0.561367154 0.97041812 1.157602031 0 0.144727635 1.902956111 0.832169601 0.189974987 0.030232626 5.13E-10 9.290196435 0.187183911 SGTGATATVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SGTGATATVSPK 12 0 Q86TU7;C9K0W5;Q6NXR6;Q86TU7-3;Q86TU7-2 Q86TU7 SETD3 Histone-lysine N-methyltransferase setd3 1 0 SGTGATAT(0.004)VS(0.996)PK 110.8 0.0036841 0 1627.8 1308.1 1628.4 1725.3 1561.8 1898.3 1538.6 1176 1711.3 1659.5 TRUE FALSE FALSE 1498.957912 1421.166335 1688.749936 1718.161166 1543.176555 1504.571182 1581.768975 1534.556986 1523.574671 1717.167501 0.872924692 0.827622427 0.983450907 1.000578665 0.898675612 0.876193604 0.921150076 0.893655968 0.887260369 1 10.74581506 -9.439922767 1.195793447 0.999546411 0.907513834 0 0.05928122 0.468065185 1.206441083 0.034955252 0.008913299 3.63E-10 9.439922767 -0.092032578 SGTLKS(ph)PPKGFDTTAINK ddPTM_HeLa_Curcumin_4h_R1 1 SGTLKSPPKGFDTTAINK 18 2 B1ALK7;A0A2R8YG42;Q14155-1;Q14155-5;E7EUY6;E7EU80;Q14155-6;Q14155-2;Q14155-3;Q14155 B1ALK7;Q14155-6 ARHGEF7 Rho guanine nucleotide exchange factor 7 1 0 S(0.006)GT(0.025)LKS(0.956)PPKGFDT(0.01)T(0.003)AINK 66.022 0.012953 42118000 1089.5 1111.5 948.85 820.21 1114.4 1329.5 1136.3 890.82 1141.9 789.04 TRUE FALSE FALSE 1003.264925 1207.573107 984.0152157 816.8161883 1101.111508 1053.746713 1168.18152 1162.426917 1016.636427 816.4590813 1.228800008 1.479036898 1.205222942 1.000437385 1.348642612 1.290630158 1.430790038 1.423741794 1.245177438 1 9.673236773 -13.35695565 0.093078019 1.00E-12 1.557550991 0.152267328 0.146057275 87.49207881 0.635695957 17.47349173 1.480434273 4.40E-14 13.35695565 1.557550991 SGTNS(ph)PPPPFSDWGR ddPTM_HeLa_Curcumin_4h_R1 1 SGTNSPPPPFSDWGR 15 0 D6RAU6;D6REP2;D6RAJ6;Q9UKT5-2;Q9UKT5 D6RAU6 FBXO4 F-box only protein 4 1 0 S(0.031)GT(0.214)NS(0.755)PPPPFSDWGR 115.04 0.0016983 61987000 3894.4 3168.6 3321.6 3684 3202.1 3663.9 3197.4 3101.3 4074.2 3630.3 TRUE FALSE FALSE 3586.154131 3442.479665 3444.701418 3668.756584 3163.917049 2903.965839 3287.110439 4046.872093 3627.270453 3756.452655 0.954665068 0.91641769 0.91700914 0.976654552 0.842261926 0.773060679 0.875057066 1.077312152 0.965610587 1 11.8751552 -7.484111302 0.644278876 0.9925418 0.89540988 0.120337789 0.076399391 0.788870655 0.72630837 0.024719614 0.024946525 3.28E-08 7.484111302 -0.097131921 SGTPTQDEMMDKPT(ph)SSSVDTMSLLSK ddPTM_HeLa_Curcumin_4h_R1 1 SGTPTQDEMMDKPTSSSVDTMSLLSK 26 1 Q5VT52-2;Q5VT52-3;Q5VT52;Q5VT52-5 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 S(0.021)GT(0.085)PT(0.063)QDEMMDKPT(0.4)S(0.12)S(0.165)S(0.05)VDT(0.095)MS(0.002)LLSK 76.237 0.0001986 117750000 1952.6 1523.3 1929.9 1881.3 1773.5 1713.7 1593.7 1121 1958.6 1660.7 TRUE FALSE FALSE 1798.04965 1654.967264 2001.423792 1873.515679 1752.352171 1358.259303 1638.414933 1462.78774 1743.74648 1718.409201 1.04634545 0.963081007 1.164695691 1.090261666 1.019752553 0.790416684 0.95344865 0.85124529 1.014744613 1 10.74685791 -5.35687563 7.191426099 1.03435645 0.874347392 0.616517637 0.063902872 0.139910833 9.154073918 0.009078852 0.020406857 4.40E-06 5.35687563 -0.160009057 SGTS(ph)SPQS(ph)PVFR ddPTM_HeLa_Curcumin_4h_R1 1 SGTSSPQSPVFR 12 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 2 0 S(0.202)GT(0.222)S(0.432)S(0.198)PQS(0.946)PVFR 111.66 0.012139 58304000 4628.8 3592.7 3761.4 4132.7 3742.4 4166 3353.8 1425.2 4844.1 3392.3 TRUE FALSE FALSE 4262.425596 3903.236979 3900.800793 4115.599982 3697.774324 3301.92464 3447.898602 1859.736919 4312.714349 3510.182172 1.214303243 1.111975615 1.111281581 1.172474755 1.053442284 0.940670449 0.982256314 0.52981208 1.22862978 1 11.77733019 -3.979630955 1.105554481 1.10600231 1.81E-16 0.828338983 0.079560524 0.996143003 0.646719955 0.013577498 1.484280311 0.000104802 3.979630955 -1.10600231 SGTSS(ph)PQS(ph)PVFR ddPTM_HeLa_Curcumin_4h_R1 1 SGTSSPQSPVFR 12 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 2 0 S(0.033)GT(0.019)S(0.107)S(0.874)PQS(0.967)PVFR 103.11 0.018208 70055000 4632.6 3774.3 4074.9 4509.3 4114.4 5063 3404 2114.8 5286.1 3740.4 TRUE FALSE FALSE 4265.924822 4100.533674 4225.919379 4490.641711 4065.338467 4012.876728 3499.507079 2759.592785 4706.228055 3870.378622 1.102198322 1.059465772 1.091862009 1.160259021 1.050372293 1.036817614 0.904176935 0.713003314 1.215960637 1 11.91825899 -4.395380269 1.725326865 1.062299659 0.645516504 0.777324337 0.063137462 0.214771441 0.765577754 0.007514204 0.134198581 4.02E-05 4.395380269 -0.416783154 SGTSSPQS(ph)PVFR ddPTM_HeLa_Curcumin_4h_R1 3 SGTSSPQSPVFR 12 0 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 0 SGTSS(0.001)PQS(0.999)PVFR;SGT(0.001)S(0.021)S(0.107)PQS(0.871)PVFR;S(0.009)GT(0.019)S(0.01)S(0.007)PQS(0.955)PVFR ;; 155.14 0.00034858 818300000 8300.6 7088.6 7285.1 8151.2 7693.1 8807.4 6664.9 4460.6 8530.6 7148.6 TRUE FALSE FALSE 7643.598751 7701.306998 7555.092215 8117.472494 7601.364807 6980.64596 6851.899156 5820.616406 7594.814523 7397.013318 1.03333581 1.041137371 1.021370638 1.097398659 1.027626216 0.943711422 0.926306181 0.786887377 1.026740685 1 12.85272716 -4.325232523 1.182088469 1.024723386 0.69978608 0.869030555 0.029695288 0.399307387 0.492390657 0.004894675 0.154465097 4.73E-05 4.325232523 -0.324937305 NVGMPVAHMES(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 NVGMPVAHMESPER 14 0 Q9UPS8 Q9UPS8 ANKRD26 Ankyrin repeat domain-containing protein 26 1 0 NVGMPVAHMES(1)PER 109.54 0.0014368 5524100 4600.3 3488.1 3557.6 4082.9 3698.6 4663.5 3102.4 859.83 4278.1 3491 TRUE FALSE FALSE 4236.181401 3789.595821 3689.447786 4066.006042 3654.496611 3696.237532 3189.444994 1121.988209 3808.803133 3612.31199 1.172706403 1.049077663 1.021353581 1.125596585 1.011678011 1.023233193 0.8829373 0.310601136 1.054394843 1 11.81870679 -4.205261467 1.806446901 1.073769466 6.88E-16 0.949833331 0.051512107 0.200981894 0.583255464 0.009914086 0.382739214 6.23E-05 4.205261467 -1.073769466 down SGTSTPTTPGS(ph)TAITPGTPPSYSSR ddPTM_HeLa_Curcumin_4h_R1 1 SGTSTPTTPGSTAITPGTPPSYSSR 25 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 S(0.003)GT(0.003)S(0.003)T(0.005)PT(0.043)T(0.131)PGS(0.429)T(0.366)AIT(0.007)PGT(0.007)PPS(0.001)YS(0.001)S(0.001)R 50.873 0.0092127 37709000 1377.6 2050.6 1873.4 1719.7 1786.5 1990.6 1918.2 1208.4 1924.5 2769.7 TRUE FALSE FALSE 1268.561506 2227.844727 1942.829852 1712.584337 1765.197154 1577.727121 1972.019529 1576.835597 1713.387165 2865.946869 0.442632597 0.777350324 0.67790156 0.597563184 0.615921102 0.550508154 0.688086563 0.550197079 0.597843311 1 11.48479615 -9.476798333 1.164123201 1.004354449 0.601957544 0 0.149262306 0.212697032 0.506643422 0.070123148 0.016447803 3.34E-10 9.476798333 -0.402396905 SGTSTPTTPGST(ph)AITPGTPPSYSSR ddPTM_HeLa_Curcumin_4h_R1 1 SGTSTPTTPGSTAITPGTPPSYSSR 25 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 SGTST(0.001)PT(0.019)T(0.088)PGS(0.358)T(0.415)AIT(0.009)PGT(0.107)PPS(0.001)YSSR 85.7 7.95E-05 52597000 2837.1 2097 1970.7 1944.5 2285 2918.7 2293.5 1577 2701.4 2368.1 TRUE FALSE FALSE 2612.540541 2278.255336 2043.735876 1936.454174 2257.752867 2313.328719 2357.849437 2057.82004 2405.063179 2450.391299 1.066172796 0.929751643 0.8340447 0.790263243 0.921384625 0.944065024 0.962233843 0.839792421 0.981501681 1 11.25879643 -7.099637826 4.603106284 1.030894715 0.885693902 0.544220472 0.054086305 0.11951802 4.210971934 0.00965676 0.011956738 7.95E-08 7.099637826 -0.145200813 RIS(ph)QVSSGETEYNPTEAR ddPTM_HeLa_Curcumin_4h_R1 1 RISQVSSGETEYNPTEAR 18 1 H7C3Y7;H0Y764;A0A494C1V1;Q6ZNJ1-2;Q6ZNJ1-3;Q6ZNJ1 H7C3Y7 NBEAL2 Neurobeachin-like protein 2 1 0 RIS(1)QVSSGETEYNPTEAR 186.98 2.19E-07 4915700 547.66 482.27 433.29 563.06 624.26 817.89 967.57 1545.3 992.02 550.54 TRUE FALSE FALSE 504.3121331 523.9552698 449.3481086 560.7302069 616.8161072 648.2503945 994.7174101 2016.454856 883.1978879 569.671224 0.885268751 0.919750284 0.788784986 0.984304952 1.082758056 1.137937756 1.746125428 3.539681787 1.550364229 1 9.153985723 -4.006607661 1.314240873 0.937573736 6.12173095 0.929998526 0.2062795 0.153863515 0.147929931 0.011680296 1.247992024 9.85E-05 4.006607661 5.184157214 up SGVSLAALK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 SGVSLAALKK 10 1 P10412;P16403;P16402 P10412;P16403;P16402 HIST1H1E;HIST1H1C;HIST1H1D Histone H1.4;Histone H1.2;Histone H1.3 0 1 SGVSLAALK(1)K 83.869 0.0061903 0 3599.5 3285.3 3035.7 2919.9 4205.7 4260.7 3450.6 2974.9 5212.9 3015.5 FALSE TRUE FALSE 3314.595777 3569.266693 3148.205712 2907.818227 4155.549774 3376.982792 3547.414549 3881.933315 4641.057912 3120.288401 1.062272249 1.143889998 1.008947029 0.93190688 1.331783874 1.082266239 1.136886753 1.244094397 1.487381074 1 11.60746366 -1 0.190439564 0.997878446 1.996101528 0 0.177788363 47.73633005 0.53432979 0.100200512 14.11112699 0.1 1 0.998223082 SGVSS(ph)DNEDDDDEEDGNYLHPSLFASK ddPTM_HeLa_Curcumin_4h_R1 2 SGVSSDNEDDDDEEDGNYLHPSLFASK 27 0 Q12872-2;Q12872 Q12872-2 SFSWAP "Splicing factor, suppressor of white-apricot homolog" 1 0 S(0.007)GVS(0.247)S(0.746)DNEDDDDEEDGNYLHPSLFASK;S(0.007)GVS(0.154)S(0.84)DNEDDDDEEDGNYLHPSLFASK ; 142.01 1.88E-08 24426600 7505.2 6594.7 5972.5 6840.8 8615.5 17892.7 8104.8 7195.2 10260.8 6838.6 TRUE FALSE FALSE 6911.155501 7164.716483 6193.846104 6812.494582 8512.765789 14181.55233 8332.198875 9388.983357 9135.215911 7076.240841 0.976670475 1.012503198 0.875301766 0.962727914 1.203006791 2.004108205 1.177489441 1.326832081 1.29097018 1 12.78876744 -5.514577517 14.43089167 0.983693454 1.492494497 0.480622124 0.222749501 0.789995576 1370.312135 0.027012255 0.056648937 3.06E-06 5.514577517 0.508801042 SGYIS(ph)ESENSEISQQVR ddPTM_HeLa_Curcumin_4h_R1 2 SGYISESENSEISQQVR 17 0 A0A075B754;Q96QE3-2;Q96QE3 A0A075B754 ATAD5 ATPase family AAA domain-containing protein 5 1 0 SGYIS(0.903)ES(0.092)ENS(0.005)EISQQVR;S(0.001)GYIS(0.943)ES(0.053)ENS(0.003)EISQQVR ; 112.01 0.0010492 4373600 2252.34 1937.09 2037.75 2297.41 1994.09 2481.48 1991.79 1265.22 2564.39 1929.17 TRUE FALSE FALSE 2074.064912 2104.523428 2113.270808 2287.903926 1970.311779 1966.793076 2047.674267 1650.979754 2283.082833 1996.208514 1.039002137 1.054260321 1.058642318 1.146124721 0.987027039 0.985264346 1.025781752 0.827057766 1.143709596 1 10.96304671 -4.260233831 6.362516162 1.028557324 0.822590103 0.550167176 0.057596464 0.063217247 14.30558729 0.006479646 0.055468922 5.49E-05 4.260233831 -0.205967222 SGYS(ph)SPGSPGTPGSR ddPTM_HeLa_Curcumin_4h_R1 2 SGYSSPGSPGTPGSR 15 0 I3L170;A0A0G2JQJ7;A0A0G2JPD5;A0A0G2JS76;A0A0G2JMX7;P10636-3;P10636-2;P10636-4;P10636-6;P10636-5;P10636-7;P10636-8;P10636;P10636-9 I3L170 MAPT Microtubule-associated protein;Microtubule-associated protein tau 1 0 SGYS(0.454)S(0.454)PGS(0.091)PGTPGSR;S(0.001)GYS(0.549)S(0.352)PGS(0.098)PGTPGSR ; 180.3 5.73E-05 38745000 5331 4348.4 4514.9 4111.4 4273.2 5637.2 4026.9 3275.4 5149.3 3838.2 TRUE FALSE FALSE 4909.045725 4724.25632 4682.226166 4094.388116 4222.244881 4467.981176 4139.883976 4274.054382 4584.434673 3971.577164 1.236044403 1.189516438 1.178933701 1.030922464 1.063115409 1.124989139 1.042377827 1.076160479 1.154310865 1 11.95549632 -6.252122523 24.80353827 1.125992412 1.069065465 0.260062484 0.064035824 1332.12778 3546416.855 0.014580982 0.023978933 5.60E-07 6.252122523 -0.056926947 SHDDGNIDLES(ph)DSFLKFDSEPSAVALELPTR ddPTM_HeLa_Curcumin_4h_R1 1 SHDDGNIDLESDSFLKFDSEPSAVALELPTR 31 1 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;P18583-8 P18583-10 SON Protein SON 1 0 SHDDGNIDLES(0.524)DS(0.452)FLKFDS(0.02)EPS(0.003)AVALELPTR 50.583 0.0041956 3383100 290.36 307.19 238.67 307.33 215.9 613.19 328.65 403.64 372.96 381.01 TRUE FALSE FALSE 267.3776996 333.7421348 247.5153202 306.0583499 213.3255335 486.0074819 337.8710345 526.7079779 332.0472211 394.2500691 0.678193158 0.846523973 0.627813004 0.776305127 0.541091937 1.232739117 0.856996767 1.335974345 0.84222489 1 8.622967198 -5.243871204 24.9872222 0.804486937 1.11341275 0.502431318 0.169786112 691.6183794 983687.4136 0.026200764 0.066634488 5.70E-06 5.243871204 0.308925812 SHDS(ph)DDS(ph)DYASSK ddPTM_HeLa_Curcumin_4h_R1 1 SHDSDDSDYASSK 13 0 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 2 0 S(0.054)HDS(0.946)DDS(0.981)DY(0.005)AS(0.008)S(0.005)K 137.73 0.0027098 7970400 3269.1 3147 2910.9 2974.4 3164.4 3939.4 2666.1 1950.3 3437.5 2928.4 TRUE FALSE FALSE 3010.347285 3419.012657 3018.780515 2962.092721 3126.666597 3122.324034 2740.903591 2544.937492 3060.41485 3030.161682 0.993460944 1.128326808 0.99624404 0.977536195 1.031848107 1.030414995 0.904540377 0.839868548 1.009984011 1 11.56517906 -4.598959216 3.626002071 1.009038506 0.850080689 0.678078195 0.041326441 0.101748014 2.544340126 0.005867531 0.027949143 2.52E-05 4.598959216 -0.158957817 SHEAEVLK ddPTM_HeLa_Curcumin_4h_R1 2 SHEAEVLK 8 0 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 0 0 ; ; 88.37 0.013829 9307200 8960.4 8461.8 8487.4 7346.4 8195.9 10219.8 7594.3 8541.3 7901.2 9148.6 FALSE FALSE TRUE 8251.174885 9193.200287 8801.95051 7316.002543 8098.169245 8100.098279 7807.375619 11145.50305 7034.458128 9466.513169 0.871617114 0.971128453 0.929798581 0.772829701 0.855454284 0.855658059 0.824736149 1.177360962 0.743088612 1 13.20861742 -9.415840726 0.881422408 1.007326712 0.896874178 0 0.132018446 1.232606503 1.520077468 0.0965248 0.018763229 3.84E-10 9.415840726 -0.110452534 SHEGETAYIR ddPTM_HeLa_Curcumin_4h_R1 4 SHEGETAYIR 10 0 J3KTL2;Q07955;J3KSR8 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 0 ;;; ;;; 185.33 3.85E-08 75338000 1625.36 1124 1235.86 1417.83 1360.25 1484.5 975.377 595.9 1407.91 1490.44 FALSE FALSE TRUE 1496.711041 1221.153552 1281.662059 1411.963395 1344.029907 1176.597966 1002.743454 777.5871668 1253.465795 1542.232679 0.970483288 0.791808894 0.831043251 0.915532017 0.871483224 0.76291858 0.650189473 0.504195753 0.812760495 1 10.59080473 -3.729997899 0.358327974 0.991259536 1.41E-18 0.672425154 0.08070115 2.395794181 0.161064854 0.019908166 1.106197231 0.00018621 3.729997899 -0.991259536 SHHAPMS(ph)PGSSGGGGQPLAR ddPTM_HeLa_Curcumin_4h_R1 4 SHHAPMSPGSSGGGGQPLAR 20 0 O14497;O14497-2 O14497 ARID1A AT-rich interactive domain-containing protein 1A 1 0 SHHAPMS(0.999)PGSSGGGGQPLAR;S(0.001)HHAPMS(0.998)PGSSGGGGQPLAR;S(0.017)HHAPMS(0.963)PGS(0.018)S(0.003)GGGGQPLAR;SHHAPMS(0.998)PGS(0.002)S(0.001)GGGGQPLAR ;;; 100.62 0.00024682 10071700 2492.04 1936.68 2271.61 2002.99 2873.52 4117.25 1682.67 2089.69 3150.96 1997.31 TRUE FALSE FALSE 2294.792404 2104.07799 2355.797865 1994.702158 2839.255151 3263.285939 1729.881192 2726.826861 2805.307571 2066.716374 1.110356715 1.018077766 1.139874777 0.96515525 1.373800095 1.578971348 0.837019154 1.319400618 1.357374242 1 11.0131247 -5.76454822 24.99934392 1.052368682 1.267397442 0.133756794 0.202953828 84.30005976 677895.6975 0.025343321 0.04737924 1.72E-06 5.76454822 0.21502876 SHILEDDENS(ph)VDISMLK ddPTM_HeLa_Curcumin_4h_R1 2 SHILEDDENSVDISMLK 17 0 O75717-2;O75717 O75717-2 WDHD1 WD repeat and HMG-box DNA-binding protein 1 1 0 SHILEDDENS(0.999)VDIS(0.001)MLK;SHILEDDENS(0.998)VDIS(0.002)MLK ; 94.958 0.0018993 160391000 13095.1 14635.5 14360.1 13845 13282.9 16936.3 15134.7 12727.2 16665.3 14912.8 TRUE FALSE FALSE 12058.60902 15900.52741 14892.29794 13787.71306 13124.51009 13423.52047 15559.33895 16607.66469 14837.15828 15431.01869 0.781452557 1.030426294 0.965088452 0.893506342 0.850527782 0.86990501 1.008315735 1.076251998 0.961515152 1 13.91354569 -4.586531641 4.074421747 0.904337742 1.064100322 0.321235915 0.071909207 0.198523153 6.40969556 0.012760178 0.057655305 2.59E-05 4.586531641 0.15976258 SHILEDDENSVDIS(ph)MLK ddPTM_HeLa_Curcumin_4h_R1 2 SHILEDDENSVDISMLK 17 0 O75717-2;O75717 O75717-2 WDHD1 WD repeat and HMG-box DNA-binding protein 1 1 0 SHILEDDENS(0.051)VDIS(0.949)MLK;SHILEDDENS(0.319)VDIS(0.681)MLK ; 107.06 0.0015985 44404000 6343.5 6438.4 6538.7 7256.9 6004.5 7908.7 6597.9 5508 8067 6367.4 TRUE FALSE FALSE 5841.405281 6994.906607 6781.029974 7226.872871 5932.900259 6268.346471 6783.019317 7187.363844 7182.070283 6588.666676 0.886583822 1.061657381 1.029196089 1.096864241 0.900470543 0.951383152 1.029498023 1.090867728 1.090064293 1 12.68577083 -7.253123435 24.93618369 0.94644236 1.018739365 0 0.07679593 768.1280095 2303309.708 0.011800842 0.014323589 5.58E-08 7.253123435 0.072297005 SHLDS(ph)PEAR ddPTM_HeLa_Curcumin_4h_R1 1 SHLDSPEAR 9 0 K7ER08;K7EP90;Q9BTD8-4;Q9BTD8-2;Q9BTD8-3;Q9BTD8 K7ER08 RBM42 RNA-binding protein 42 1 0 SHLDS(1)PEAR 129.74 0.0018708 17125000 3177.6 2545 2509.4 2844 2826.4 5204.1 5148.5 3243.4 3069.9 2074.2 TRUE FALSE FALSE 2926.089607 2764.97846 2602.400571 2832.232282 2792.697026 4124.710998 5292.953054 4232.297729 2733.139651 2146.278296 1.363331872 1.288266515 1.212517769 1.319601604 1.301181227 1.921796911 2.466107524 1.971924022 1.273432088 1 11.06762144 -5.189374496 2.662040405 1.200175076 2.223990234 0.877706019 0.15050156 0.07246086 0.997041401 0.025446583 0.075164731 6.47E-06 5.189374496 1.023815158 SHLEPSGNPLPATPTTSAPSAPPAS(ph)SQGPDTAPRPSPPQEEAR ddPTM_HeLa_Curcumin_4h_R1 1 SHLEPSGNPLPATPTTSAPSAPPASSQGPDTAPRPSPPQEEAR 43 1 Q8N1F8 Q8N1F8 STK11IP Serine/threonine-protein kinase 11-interacting protein 1 0 SHLEPSGNPLPAT(0.002)PT(0.011)T(0.011)S(0.011)APS(0.108)APPAS(0.358)S(0.358)QGPDT(0.108)APRPS(0.034)PPQEEAR 62.822 1.09E-05 20171000 1911.5 1953.5 1602 1564.2 2023.7 2437.8 1603.8 1234.4 1598.4 1693 TRUE FALSE FALSE 1760.202758 2122.351835 1661.371529 1557.727755 1999.568699 1932.1728 1648.798312 1610.762878 1423.059519 1751.831624 1.004778504 1.211504466 0.948362563 0.889199472 1.141416031 1.102944355 0.941185379 0.91947357 0.812326653 1 10.7746484 -7.487579036 24.9296755 1.002108057 1.025058837 0.01821937 0.11528731 2428.384826 1715012.06 0.017171479 0.019072263 3.25E-08 7.487579036 0.02295078 SHLGNVHDQDN ddPTM_HeLa_Curcumin_4h_R1 1 SHLGNVHDQDN 11 0 Q8WW12;Q8WW12-3 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 0 0 82.489 0.010979 399150 129.6 0 154.62 0 160.37 0 56.145 0 0 0 FALSE FALSE TRUE 119.3420232 0 160.3503532 0 158.4576925 0 57.72027759 0 0 0 0 SHNVAAGS(ph)YEAPLPPGS(ph)FHGDFAYGTYR ddPTM_HeLa_Curcumin_4h_R1 1 SHNVAAGSYEAPLPPGSFHGDFAYGTYR 28 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;X6RGP5;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 2 0 S(0.009)HNVAAGS(0.969)Y(0.022)EAPLPPGS(0.998)FHGDFAYGT(0.002)YR 106.36 1.63E-06 0 720.53 853.9 824.38 741.9 831.52 1006.8 452.61 303.61 954.38 811.06 TRUE FALSE FALSE 663.4992902 927.7073111 854.932248 738.8302144 821.6046671 797.978331 465.3090185 396.1792914 849.6869017 839.2442746 0.790591381 1.105407971 1.018692976 0.880351808 0.978981557 0.950829639 0.554438121 0.472066719 1.012442893 1 9.71294698 -4.719150539 5.015143584 0.929213833 0.497364291 0.805010711 0.087990348 0.072749403 4.113136455 0.014474466 0.055457128 1.91E-05 4.719150539 -0.431849542 SHNVAAGSYEAPLPPGS(ph)FHGDFAYGTYR ddPTM_HeLa_Curcumin_4h_R1 1 SHNVAAGSYEAPLPPGSFHGDFAYGTYR 28 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;X6RGP5;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 SHNVAAGS(0.001)Y(0.002)EAPLPPGS(0.863)FHGDFAY(0.043)GT(0.048)Y(0.043)R 56.234 0.0019662 5072600 603.94 697.07 596.15 455.35 423.3 842.02 540.51 505.76 729.05 606.21 TRUE FALSE FALSE 556.1375117 757.3216247 618.2438434 453.4658824 418.252424 667.3755605 555.6752559 659.9638958 649.075039 627.2757524 0.886591757 1.207318507 0.985601374 0.722913138 0.666776011 1.063926922 0.885854831 1.052111282 1.034752318 1 9.292955985 SHPAMS(ph)PGTPGPTMGR ddPTM_HeLa_Curcumin_4h_R1 3 SHPAMSPGTPGPTMGR 16 0 A0A3F2YNW7;Q8NFD5;Q8NFD5-2;Q8NFD5-3;A0A1B0GUC6;A0A1B0GUG2;A0A1B0GU09;A0A6I8PTU7 A0A3F2YNW7 ARID1B AT-rich interactive domain-containing protein 1B 1 0 SHPAMS(0.999)PGT(0.001)PGPTMGR;SHPAMS(0.999)PGT(0.001)PGPTMGR;S(0.004)HPAMS(0.968)PGT(0.028)PGPTMGR ;; 96.561 0.0016306 29479800 6255.4 5130.7 5911.1 6534.3 5820.4 6812.1 4639.3 5022.3 5731.6 5840.1 TRUE FALSE FALSE 5760.278489 5574.174846 6130.170566 6507.262798 5750.995531 5399.193672 4769.466272 6553.57615 5102.85782 6043.04304 0.953208251 0.922411906 1.014417823 1.076818873 0.951672112 0.893456101 0.789249099 1.084482786 0.844418579 1 12.5610595 -5.518629619 24.93980406 0.983280299 0.911328428 0.031725181 0.088935729 236.8506291 1390165.77 0.010596859 0.021613512 3.03E-06 5.518629619 -0.071951871 SHPAMSPGT(ph)PGPTMGR ddPTM_HeLa_Curcumin_4h_R1 2 SHPAMSPGTPGPTMGR 16 0 A0A3F2YNW7;Q8NFD5;Q8NFD5-2;Q8NFD5-3;A0A1B0GUC6;A0A1B0GUG2;A0A1B0GU09;A0A6I8PTU7 A0A3F2YNW7 ARID1B AT-rich interactive domain-containing protein 1B 1 0 SHPAMS(0.001)PGT(0.997)PGPT(0.002)MGR;SHPAMS(0.025)PGT(0.947)PGPT(0.028)MGR ; 72.968 0.0059232 4344000 1221.78 908.61 1122.46 932.15 1102.6 1262.39 1366.45 536.57 1299.43 1128.37 TRUE FALSE FALSE 1125.074824 987.1461997 1164.059355 928.2930103 1089.452215 1000.556084 1404.788909 700.1677229 1156.88578 1167.580774 0.963594853 0.845462877 0.996984004 0.79505678 0.933085093 0.856948064 1.203162078 0.599673906 0.99084004 1 10.18930664 -7.461576719 5.776142214 0.984314092 0.902733639 0.079712164 0.144639075 0.452372594 29.46393939 0.022329074 0.025120351 3.45E-08 7.461576719 -0.081580453 SHPLDLS(ph)PNVQSR ddPTM_HeLa_Curcumin_4h_R1 2 SHPLDLSPNVQSR 13 0 H0YBM4;H0YBF7;A0A0A0MRE5;Q9ULH1;Q9ULH1-2 H0YBM4 ASAP1 "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1" 1 0 SHPLDLS(0.998)PNVQS(0.002)R;SHPLDLS(0.998)PNVQS(0.002)R ; 87.419 0.0070598 12365000 10932.7 10040.4 10101.8 10948.8 10769.3 9825.7 7566.5 8620.1 10965.6 10506.7 TRUE FALSE FALSE 10067.36526 10908.24744 10476.18159 10903.49677 10640.88313 7787.739062 7778.795626 11248.32881 9762.701115 10871.80704 0.926006617 1.003351825 0.963609964 1.002914853 0.978759381 0.716324253 0.715501627 1.034632859 0.897983295 1 13.40830414 -5.283419165 24.29578852 0.970844312 0.811487786 0.359153244 0.08856219 366.6818272 405318.5246 0.011636829 0.026043301 5.21E-06 5.283419165 -0.159356527 SHPLDPIDTVDFER ddPTM_HeLa_Curcumin_4h_R1 1 SHPLDPIDTVDFER 14 0 A0A1B0GVU9;P47897-2;P47897;A0A0U1RQM8;A0A0U1RQU2;A0A0U1RRI9;A0A0U1RQE9;A0A0U1RQL2;C9J165;A0A0U1RQT0 A0A1B0GVU9 QARS Glutamine--tRNA ligase 0 0 103.13 0.0032049 7683200 5275.3 5651.2 4574.4 4734.3 4690.9 6593.5 4688.2 4141.8 5103.3 4824.2 FALSE FALSE TRUE 4857.754439 6139.664547 4743.931288 4714.710721 4634.964081 5225.933776 4819.738274 5404.615753 4543.480758 4991.840591 0.973138935 1.229940026 0.950337095 0.94448343 0.928508032 1.046895164 0.965523275 1.082689973 0.91018146 1 12.28535615 -5.257862344 0.010694945 0.78092046 1.232893487 0.022086195 0.089791393 28044.51858 68.57513832 1374.748177 1525.40372 5.52E-06 5.257862344 0.451973027 SHS(ph)APSEVGFSDAR ddPTM_HeLa_Curcumin_4h_R1 1 SHSAPSEVGFSDAR 14 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 S(0.008)HS(0.495)APS(0.495)EVGFS(0.002)DAR 148.41 0.00055327 13091000 1219.7 1191 1135.2 1426.2 1654.9 1462.2 923.1 463.86 1505.5 1009.6 TRUE FALSE FALSE 1123.159458 1293.944733 1177.271511 1420.298762 1635.166398 1158.923238 948.9997016 605.2887787 1340.350417 1044.683525 1.075119336 1.238599731 1.126916892 1.359549307 1.565226559 1.109353417 0.908408795 0.579399181 1.283020537 1 10.02885024 -4.416282191 2.536173838 1.121455993 0.548611873 0.520282546 0.176534292 0.2830526 2.802232509 0.028138924 0.295530395 3.83E-05 4.416282191 -0.572844121 SHS(ph)DTSIASR ddPTM_HeLa_Curcumin_4h_R1 1 SHSDTSIASR 10 0 H7C3H3;E9PEM3;H7C357;H0Y6E6;Q92622-3;Q92622-2;Q92622 H7C3H3 KIAA0226 Run domain Beclin-1 interacting and cysteine-rich containing protein 1 0 S(0.229)HS(0.771)DTSIASR 110.64 0.0034645 6000700 345.32 304.04 203.82 193.79 366 360.54 220.47 185.14 307.11 311.2 TRUE FALSE FALSE 317.9875576 330.3198628 211.3737485 192.9881483 361.635689 285.7599399 226.6557948 241.5883337 273.4208014 322.0141768 0.987495522 1.02579292 0.656411313 0.599315689 1.123042757 0.887414159 0.703868994 0.750241297 0.84909554 1 8.330980395 -6.782265398 24.99770025 0.996307478 0.794296539 0.260305094 0.143709753 207.6111558 249197.2074 0.022374493 0.029422967 1.65E-07 6.782265398 -0.202010939 SHS(ph)PSASQSGSQLR ddPTM_HeLa_Curcumin_4h_R1 4 SHSPSASQSGSQLR 14 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 S(0.003)HS(0.717)PS(0.243)AS(0.011)QS(0.021)GS(0.005)QLR;S(0.018)HS(0.975)PS(0.007)ASQSGSQLR;S(0.029)HS(0.969)PS(0.002)ASQSGSQLR;S(0.051)HS(0.945)PS(0.004)ASQSGSQLR ;;; 161.49 0.00027062 82449400 9281.26 8551.1 7410.89 7949.68 10319.43 14714.5 8059.95 5140.43 11879.1 8929.85 TRUE FALSE FALSE 8546.638477 9290.218981 7685.544103 7916.786331 10196.37754 11662.54683 8286.090505 6707.723443 10575.99245 9240.161623 0.924944695 1.005417368 0.831754294 0.856780071 1.103484761 1.262158316 0.896747356 0.725931398 1.144567907 1 13.17370237 -4.361505301 4.300700792 0.978149416 0.727124835 0.291334052 0.128892658 0.204576871 5.876770461 0.01674849 0.115518843 4.35E-05 4.361505301 -0.251024581 SHS(ph)S(ph)LPPNNSYADFER ddPTM_HeLa_Curcumin_4h_R1 1 SHSSLPPNNSYADFER 16 0 O43293 O43293 DAPK3 Death-associated protein kinase 3 2 0 S(0.019)HS(0.977)S(0.964)LPPNNS(0.039)YADFER 90.498 0.012953 9625300 2482.9 1917.4 2457.1 2349.6 2682.1 2984.9 2262.2 1336.6 2589.5 1868.4 TRUE FALSE FALSE 2286.375845 2083.131512 2548.162287 2339.877978 2650.117709 2365.798093 2325.671244 1744.123187 2305.438329 1933.326761 1.182612216 1.07748548 1.318019457 1.210285827 1.370755199 1.223692829 1.202937491 0.90213575 1.192472155 1 10.91686978 -8.953700523 0.614293821 0.987470817 1.201185237 0 0.134496986 0.973932848 0.63159697 0.109866943 0.028368057 1.11E-09 8.953700523 0.21371442 SHS(ph)SLPPNNSYADFER ddPTM_HeLa_Curcumin_4h_R1 1 SHSSLPPNNSYADFER 16 0 O43293 O43293 DAPK3 Death-associated protein kinase 3 1 0 S(0.319)HS(0.362)S(0.319)LPPNNSYADFER 67.43 0.013533 11928000 2736.6 1606.2 1963.8 2439.4 2649.5 2966.5 2094.2 1652.5 2665.5 2219.1 TRUE FALSE FALSE 2519.995222 1745.032771 2036.580156 2429.306409 2617.906443 2351.214461 2152.957616 2156.339643 2373.101319 2296.21356 1.097456816 0.759961008 0.886929766 1.057961878 1.14009711 1.023952868 0.937612099 0.93908497 1.033484585 1 11.16504111 KPNIFYSGPAS(ph)PARPR ddPTM_HeLa_Curcumin_4h_R1 2 KPNIFYSGPASPARPR 16 2 Q6PL18;Q6PL18-2 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 1 0 KPNIFYSGPAS(1)PARPR;KPNIFYSGPAS(1)PARPR ; 129.98 0.00033728 194883000 7977.2 6156.6 6471.8 7453.8 6671.8 6897.8 4907.6 2093.75 7610.7 7092.9 TRUE FALSE FALSE 7345.796202 6688.749071 6711.650601 7422.958151 6592.243142 5467.118526 5045.294048 2732.124737 6775.825251 7339.377747 1.000874523 0.911350976 0.91447134 1.011387941 0.898201914 0.744902186 0.687428038 0.372255637 0.923215221 1 12.84144204 -4.204040497 0.729481256 0.99247602 8.67E-19 0.929353287 0.049902835 0.438135442 0.154479518 0.007446849 0.362905168 6.25E-05 4.204040497 -0.99247602 down SHS(ph)SSEAYEPR ddPTM_HeLa_Curcumin_4h_R1 2 SHSSSEAYEPR 11 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 S(0.195)HS(0.711)S(0.092)S(0.003)EAYEPR;S(0.001)HS(0.799)S(0.195)S(0.004)EAYEPR ; 116.63 0.0021911 29026000 2729.92 3819.33 2527.5 2480.39 2976.05 4413.7 2909.32 2908.19 3001.2 2883.35 TRUE FALSE FALSE 2513.843951 4149.455867 2621.171373 2470.126803 2940.562547 3498.248867 2990.947689 3794.883743 2671.975869 2983.546198 0.842569139 1.390779828 0.878542245 0.827916392 0.9855931 1.172513725 1.00248077 1.271937316 0.895570469 1 11.5428124 -1.000000029 0.524477178 0.949617436 12.12096628 0.196699714 0.162694901 120.9822621 1.087890374 0.031175664 1514.361331 0.099999993 1.000000029 11.17134885 SRS(ph)SDIVSSVR ddPTM_HeLa_Curcumin_4h_R1 1 SRSSDIVSSVR 11 1 Q14C86-4;Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;F8W9S7;Q14C86-3;H0Y4E7;H0Y7I9;C9IZ08 Q14C86-4 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 0 S(0.048)RS(0.476)S(0.476)DIVSSVR 105.19 0.0037103 46355000 1141.9 845.02 1048.3 1160.1 1019.3 1890.7 1852.5 3203.2 1360.3 1254.2 TRUE FALSE FALSE 1051.51741 918.0597635 1087.15092 1155.299814 1007.145513 1498.547507 1904.476164 4179.840934 1211.078493 1297.783357 0.810241097 0.707406023 0.837698307 0.890210071 0.77605057 1.154697739 1.467483887 3.220753998 0.933190033 1 10.34183385 -4.005824522 1.425273199 0.879583465 5.53854215 0.980107173 0.100384501 0.23937102 0.271131145 0.016898715 1.885425628 9.87E-05 4.005824522 4.658958685 up KLS(ph)SSDAPAQDTGSSAAAVETDASR ddPTM_HeLa_Curcumin_4h_R1 2 KLSSSDAPAQDTGSSAAAVETDASR 25 1 A0A1B0GV47;Q7Z4S6-6;Q7Z4S6-5;Q7Z4S6-2;Q7Z4S6;Q7Z4S6-4;H0YHT2;Q7Z4S6-3;H0YIM6 A0A1B0GV47 KIF21A Kinesin-like protein KIF21A 1 0 KLS(0.539)S(0.231)S(0.231)DAPAQDTGSSAAAVETDASR;KLS(0.333)S(0.333)S(0.333)DAPAQDTGSSAAAVETDASR ; 129.04 1.81E-08 248986000 3771.4 2976.2 3333.2 3427.9 3734 5379.2 4958.3 8344.3 4152.8 3709.9 TRUE FALSE FALSE 3472.88971 3233.449466 3456.731324 3413.716258 3689.474489 4263.493284 5097.416553 10888.43866 3697.24823 3838.818749 0.904676656 0.842303239 0.900467449 0.889262161 0.961096298 1.110626357 1.327860701 2.836403428 0.963121333 1 11.90644673 -4.004986143 1.552770865 0.938849683 4.723933404 0.987917817 0.062661534 0.173063746 0.232998814 0.010245036 1.201882693 9.89E-05 4.004986143 3.78508372 up SHSAPS(ph)EVGFSDAR ddPTM_HeLa_Curcumin_4h_R1 1 SHSAPSEVGFSDAR 14 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 S(0.056)HS(0.151)APS(0.785)EVGFS(0.008)DAR 130.19 0.001086 16627000 688.01 616.24 771.16 674.95 734.35 1005.6 590.59 313.57 918.53 720.5 TRUE FALSE FALSE 633.5532825 669.5050397 799.739868 672.1572357 725.5933559 797.0272246 607.1603659 409.1760495 817.769557 745.5373214 0.849794188 0.8980168 1.07270266 0.901574229 0.97324887 1.069064152 0.814392987 0.548833758 1.096886143 1 9.542136765 -4.364614311 3.211808074 0.944437423 0.530900583 0.691949463 0.086103932 0.119499961 1.958652596 0.011290869 0.104596113 4.32E-05 4.364614311 -0.41353684 SHSESASPSALSS(ph)SPNNLSPTGWSQPK ddPTM_HeLa_Curcumin_4h_R1 1 SHSESASPSALSSSPNNLSPTGWSQPK 27 0 H7C155;P04049;P04049-2 H7C155 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 0 SHSESASPSALS(0.089)S(0.453)S(0.453)PNNLS(0.005)PT(0.001)GWSQPK 112.61 1.57E-08 11868000 1768.4 1513.9 1219.2 1161.2 2749.4 3567.9 1293.7 341.51 2516.7 1281.9 TRUE FALSE FALSE 1628.429274 1644.75477 1264.384625 1156.395262 2716.615201 2827.877321 1329.99774 445.6348269 2240.624306 1326.44593 1.227663516 1.239971214 0.953212337 0.871799774 2.048040663 2.131920539 1.00267769 0.335961547 1.68919385 1 10.37335015 SHSESASPSALSSS(ph)PNNLSPTGWSQPK ddPTM_HeLa_Curcumin_4h_R1 1 SHSESASPSALSSSPNNLSPTGWSQPK 27 0 H7C155;P04049;P04049-2 H7C155 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 0 SHSESASPSALS(0.007)S(0.148)S(0.83)PNNLS(0.015)PTGWSQPK 132.86 1.45E-08 12826000 2876.1 2087.1 1616.9 1855.8 3489.3 4970.7 1776.7 521.58 3432 1997.3 TRUE FALSE FALSE 2648.45365 2267.499624 1676.823736 1848.121191 3447.692376 3939.720789 1826.54942 680.6073409 3055.518186 2066.706026 1.281485425 1.097156342 0.811350872 0.894235159 1.668206476 1.906280206 0.883797404 0.329319861 1.478448385 1 11.01311748 -9.707796013 1.608403267 1.000115478 1.154817352 0 0.448377923 1.939881885 9.06593642 0.313454734 0.069194221 1.96E-10 9.707796013 0.154701874 SHSLS(ph)RPGPTEGDAEGEAEGPVGSTLGSYATLTR ddPTM_HeLa_Curcumin_4h_R1 1 SHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTR 34 1 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 0 S(0.128)HS(0.128)LS(0.729)RPGPT(0.014)EGDAEGEAEGPVGSTLGSYATLTR 42.325 0.0095152 13052000 1124.4 961.98 1149.9 983.1 1206.9 1371.6 801.27 781.08 1227.1 1218.7 TRUE FALSE FALSE 1035.402554 1045.129265 1192.516306 979.0321927 1192.508506 1087.114699 823.7514797 1019.227696 1092.4902 1261.049734 0.821064012 0.828777198 0.945653667 0.776362871 0.945647482 0.862071233 0.653226798 0.808237509 0.866333952 1 10.30040946 -13.52287875 0.17058595 1.695806213 0.779950738 0.147271257 0.086812077 43.02976711 0.478395984 10.00710655 0.126307839 3.00E-14 13.52287875 -0.915855476 SHT(ph)SEGAHLDITPNSGAAGNSAGPK ddPTM_HeLa_Curcumin_4h_R1 1 SHTSEGAHLDITPNSGAAGNSAGPK 25 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 0 S(0.302)HT(0.349)S(0.349)EGAHLDITPNSGAAGNSAGPK 83.236 6.65E-05 15986000 2868.6 3068.2 5633.4 2232 3266.5 3087.4 2366.2 1623.1 2605.2 1797.8 TRUE FALSE FALSE 2641.547283 3333.401536 5842.17876 2222.764575 3227.549121 2447.038438 2432.589204 2117.975718 2319.416078 1860.273416 1.419977977 1.79188796 3.140494676 1.194859076 1.734986423 1.315418699 1.307651436 1.138529261 1.246814612 1 10.86129896 -2.458217862 14.88194713 1.404943507 1.262389808 0 0.599382572 0 0 0.083871558 0 0.003481626 2.458217862 -0.1425537 SHTEEDCTEELFDFLHAR ddPTM_HeLa_Curcumin_4h_R1 1 SHTEEDCTEELFDFLHAR 18 0 P07919 P07919 UQCRH "Cytochrome b-c1 complex subunit 6, mitochondrial" 0 0 195.5 1.10E-09 3605200 2611.5 2214.8 2710.7 3107 2433.6 2557.9 1260 1005.8 3296.1 2754.4 FALSE FALSE TRUE 2404.797019 2406.237443 2811.160927 3094.144057 2404.580909 2027.362707 1295.352209 1312.46379 2934.526076 2850.115195 0.843754324 0.844259715 0.986332388 1.085620701 0.843678499 0.711326584 0.454491177 0.460494998 1.029616656 1 11.47680452 -5.004199013 1.979800061 0.932383968 0.441389321 0.862209634 0.078793441 0.100180413 0.749164368 0.012695511 0.052138861 9.90E-06 5.004199013 -0.490994648 SHTPS(ph)PTSPK ddPTM_HeLa_Curcumin_4h_R1 2 SHTPSPTSPK 10 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 0 SHTPS(0.971)PT(0.023)S(0.006)PK;S(0.002)HT(0.001)PS(0.808)PT(0.15)S(0.039)PK ; 95.273 0.0074246 15785000 10621.1 9626.4 9516.1 9925 9621.7 11031.3 8752.3 7951 10813.4 9172.2 TRUE FALSE FALSE 9780.428728 10458.46312 9868.775037 9883.93298 9506.967512 8743.284032 8997.865982 10375.2233 9627.197074 9490.933267 1.030502318 1.101942541 1.039810813 1.04140791 1.001689428 0.921224898 0.948048598 1.093172084 1.014357261 1 13.21233424 -5.524637032 23.13540494 1.025667533 0.979858318 0.151744568 0.049361457 32.22922375 424075.7132 0.007260878 0.014627864 2.99E-06 5.524637032 -0.045809214 SHTPSPT(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 SHTPSPTSPK 10 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 0 SHTPSPT(0.621)S(0.379)PK 136.01 0.0019658 288650000 8218.4 6577.4 6732.6 6793.4 8056.9 8169.1 6618.1 6576.1 7683 6417.1 TRUE FALSE FALSE 7567.904968 7145.921148 6982.116079 6765.290711 7960.82673 6474.736575 6803.786074 8581.122617 6840.194122 6640.093747 1.139728633 1.07617775 1.05150866 1.018854698 1.198902761 0.975097163 1.024652111 1.292319498 1.030135173 1 12.69698789 -9.518065314 1.258100744 0.999748634 1.095069284 0.116371992 0.08932571 0.728582366 2.055810922 0.059718014 0.014200582 3.03E-10 9.518065314 0.095320649 SHTPSPTS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SHTPSPTSPK 10 0 B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 B7Z385 CAP2 Adenylyl cyclase-associated protein;Adenylyl cyclase-associated protein 2 1 0 SHTPSPT(0.409)S(0.591)PK;SHTPSPT(0.229)S(0.771)PK ; 106.54 0.0042973 117505000 11117.6 9897.4 9991.4 9994.6 11727.7 12295.2 9910.4 9915.6 10786.3 9695.5 TRUE FALSE FALSE 10237.63023 10752.88715 10361.69007 9953.244993 11587.85484 9745.036925 10188.45915 12938.82079 9603.069876 10032.4179 1.020454922 1.071814119 1.032820819 0.992108292 1.155041083 0.971354764 1.015553703 1.289701139 0.957203933 1 13.29238173 -4.260623858 24.79479718 1.021790098 1.289701232 0.690190882 0.053377424 23.19256689 704994.046 0.006477385 0.052399215 5.49E-05 4.260623858 0.267911134 SHVEDGDIAGAPAS(ph)SPEAPPAEQDPVQLK ddPTM_HeLa_Curcumin_4h_R1 1 SHVEDGDIAGAPASSPEAPPAEQDPVQLK 29 0 A0A087WVV2;Q9P2E9-3;Q9P2E9;F8W7S5;A0A087WU26 A0A087WVV2 RRBP1 Ribosome-binding protein 1 1 0 SHVEDGDIAGAPAS(0.5)S(0.5)PEAPPAEQDPVQLK 142.01 3.73E-12 61015000 3516.1 2072.8 2674.8 3066.6 3345.8 3625.4 2002.3 1947.3 3929.8 2751.4 TRUE FALSE FALSE 3237.796975 2251.963596 2773.930441 3053.911222 3305.90352 2873.451173 2058.479149 2541.022806 3498.710772 2847.010945 1.137261864 0.790992251 0.974330796 1.072672807 1.161183987 1.009287013 0.723031695 0.89252302 1.228906681 1 11.47523232 -4.857750488 6.275442405 1.045618047 0.809607295 0.39252781 0.119527095 0.139413356 7.527050594 0.015478237 0.047696909 1.39E-05 4.857750488 -0.236010752 SHVEDGDIAGAPASS(ph)PEAPPAEQDPVQLK ddPTM_HeLa_Curcumin_4h_R1 1 SHVEDGDIAGAPASSPEAPPAEQDPVQLK 29 0 A0A087WVV2;Q9P2E9-3;Q9P2E9;F8W7S5;A0A087WU26 A0A087WVV2 RRBP1 Ribosome-binding protein 1 1 0 SHVEDGDIAGAPAS(0.137)S(0.863)PEAPPAEQDPVQLK 178.94 1.50E-20 61829000 2949.4 2026.9 2215.6 3201.4 2431.3 3276.2 1689.3 1757.9 3679.7 2305.9 TRUE FALSE FALSE 2715.951878 2202.096204 2297.712085 3188.153455 2402.308335 2596.67919 1736.697211 2293.875618 3276.046116 2386.029853 1.138272379 0.92291226 0.962985472 1.336175007 1.006822413 1.088284451 0.727860638 0.961377585 1.373011369 1 11.22039638 -4.777236576 24.98484776 1.065523888 0.844619105 0.285541927 0.154747389 165.7176318 262100.162 0.016469131 0.049645603 1.67E-05 4.777236576 -0.220904783 SHVTEEEEEEEEEES(ph)DS ddPTM_HeLa_Curcumin_4h_R1 3 SHVTEEEEEEEEEESDS 17 0 O75971-2;O75971 O75971-2 SNAPC5 snRNA-activating protein complex subunit 5 1 0 SHVTEEEEEEEEEES(0.5)DS(0.5);SHVTEEEEEEEEEES(0.5)DS(0.5);SHVTEEEEEEEEEES(0.5)DS(0.5) ;; 176.48 1.16E-05 40379500 5743.56 4535.95 4143.19 5222.7 5397.84 6596.57 4532.09 3774.74 5986.34 4878.55 TRUE FALSE FALSE 5288.951165 4928.017306 4296.740266 5201.089851 5333.474283 5228.367023 4659.248248 4925.640849 5329.653479 5048.079249 1.047715558 0.976216312 0.851163394 1.030310658 1.056535371 1.035714133 0.922974466 0.975745547 1.055778488 1 12.30151884 -7.239754947 23.04938074 1.022532346 0.978564517 0.155411112 0.057969962 525.6891851 558778.974 0.010041332 0.01228992 5.76E-08 7.239754947 -0.04396783 SHWDDS(ph)TSDS(ph)ELEK ddPTM_HeLa_Curcumin_4h_R1 1 SHWDDSTSDSELEK 14 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 2 0 S(0.096)HWDDS(0.629)T(0.122)S(0.158)DS(0.995)ELEK 101.3 0.011302 5747300 2110.2 1602.3 1896.3 2059.6 2227.8 2891.6 1995.6 1682.5 2171.2 1851.1 TRUE FALSE FALSE 1943.175443 1740.795672 1966.578546 2051.077921 2201.23494 2291.849565 2051.591165 2195.486505 1933.024792 1915.425587 1.014487567 0.908829705 1.026705793 1.070820989 1.149214543 1.196522371 1.071088942 1.146213416 1.009188143 1 10.90344926 -6.068113263 2.496090168 0.999149138 1.139175211 0.739231458 0.041636328 0.117130495 1.439412236 0.006369084 0.011676738 8.55E-07 6.068113263 0.140026073 SHWDDSTS(ph)DS(ph)ELEK ddPTM_HeLa_Curcumin_4h_R1 1 SHWDDSTSDSELEK 14 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 2 0 S(0.001)HWDDS(0.208)T(0.36)S(0.472)DS(0.959)ELEK 86.756 0.0077358 0 2200.7 2052.5 1820.2 2194.9 2205.6 2640.3 1685.7 1373.8 2549.1 2422.6 TRUE FALSE FALSE 2026.512273 2229.908954 1887.658213 2185.818085 2179.299661 2092.672018 1732.996205 1792.665296 2269.470108 2506.78517 0.808410827 0.889549285 0.753019539 0.871960674 0.869360361 0.834803095 0.691322187 0.71512522 0.905330913 1 11.29162265 -13.52287875 0.13802202 1.698508849 0.720104261 0.505429371 0.062949382 36.7423057 0.354174818 7.041711114 0.185895427 3.00E-14 13.52287875 -0.978404588 SHWDDSTS(ph)DSELEK ddPTM_HeLa_Curcumin_4h_R1 2 SHWDDSTSDSELEK 14 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 SHWDDST(0.011)S(0.989)DSELEK;SHWDDS(0.002)T(0.349)S(0.648)DS(0.001)ELEK ; 171.15 9.47E-05 66262000 15199.6 11838.8 11901.9 13120.8 13075.8 15072.1 12530.6 11086.5 15651.3 13506.8 TRUE FALSE FALSE 13996.53562 12862.09312 12342.99488 13066.50961 12919.87963 11945.97656 12882.17491 14466.72281 13934.39155 13976.16029 1.001457863 0.920288037 0.883146345 0.93491412 0.924422685 0.854739521 0.921724897 1.035099949 0.997011429 1 13.77068044 -7.26133644 22.46972904 1.000688439 0.920844388 0.377432857 0.043671229 1.561741221 340803.9685 0.007145191 0.008459029 5.48E-08 7.26133644 -0.079844051 VSS(ph)PVFGATSSIK ddPTM_HeLa_Curcumin_4h_R1 2 VSSPVFGATSSIK 13 0 F6Q6H0;I6L8A6;Q99708-3;Q99708;Q99708-2 F6Q6H0 RBBP8 DNA endonuclease RBBP8 1 0 VS(0.012)S(0.988)PVFGATSSIK;VS(0.05)S(0.949)PVFGAT(0.001)SSIK ; 124.3 0.00211 109280000 5823 4305.9 4355.3 5201 4636.8 5806.8 4105.6 1033.39 5571.8 4586.2 TRUE FALSE FALSE 5362.103406 4678.082809 4516.711249 5179.47964 4581.509188 4602.404224 4220.792086 1348.465854 4960.58748 4745.570109 1.129917646 0.985778885 0.951774212 1.091434648 0.965428617 0.969831678 0.889417286 0.284152551 1.045309071 1 12.2123657 -4.203138849 1.942010943 1.041472933 9.46E-17 0.935083628 0.057505153 0.188416757 0.653553666 0.009913972 0.368079421 6.26E-05 4.203138849 -1.041472933 down ASVS(ph)GPNSPS(ph)ETRR ddPTM_HeLa_Curcumin_4h_R1 1 ASVSGPNSPSETRR 14 1 C9J453;A0A087X255;O15344-2;O15344;A0A087X0X0 C9J453 MID1 E3 ubiquitin-protein ligase Midline-1 2 0 AS(0.07)VS(0.792)GPNS(0.318)PS(0.745)ET(0.075)RR 109.79 0.0046084 65352000 4550.7 3346.6 3507.5 3861.9 3824 4528.5 3444.3 831.08 3977.9 4164.4 TRUE FALSE FALSE 4190.507293 3635.865192 3637.491036 3845.920481 3778.401298 3589.238053 3540.937788 1084.472466 3541.534322 4309.11259 0.972475702 0.843761938 0.844139242 0.892508701 0.876839771 0.832941349 0.821732483 0.251669559 0.821870918 1 12.07317508 -4.203120932 1.811845008 0.946088635 1.69E-31 0.84606394 0.07731135 0.272113975 0.792188953 0.011766252 0.458394375 6.26E-05 4.203120932 -0.946088635 down SIDDLEEK ddPTM_HeLa_Curcumin_4h_R1 2 SIDDLEEK 8 0 P09493-3;P09493-9;H7BYY1;Q6ZN40;P09493-2;P09493-8;P09493-7 P09493-3 TPM1 Tropomyosin alpha-1 chain 0 0 ; ; 160.63 3.77E-06 20919300 10418.9 8569.4 9923.6 9166.9 8894 11687.4 8677.7 9603.5 10395.4 8176.6 FALSE FALSE TRUE 9594.233071 9310.100751 10291.37735 9128.969797 8787.944859 9263.301496 8921.172907 12531.56294 9255.050628 8460.736241 1.133971418 1.10038896 1.216369008 1.078980545 1.038673776 1.094857614 1.054420402 1.481143317 1.093882419 1 13.04656749 GAASTLVPGVS(ph)ETSASPGSPSVR ddPTM_HeLa_Curcumin_4h_R1 1 GAASTLVPGVSETSASPGSPSVR 23 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 0 GAAST(0.002)LVPGVS(0.528)ET(0.356)S(0.04)AS(0.072)PGS(0.002)PSVR 221.81 1.87E-23 48388000 10458 7779.5 8513.8 9375 8957.3 9913.4 6755.3 2402.1 10052 8838.9 TRUE FALSE FALSE 9630.238265 8451.925315 8829.328918 9336.208734 8850.490048 7857.249093 6944.835537 3134.489232 8949.320749 9146.051117 1.052939475 0.924106503 0.965370607 1.020791226 0.967684297 0.859086505 0.759326123 0.342715035 0.97849013 1 13.15893327 -4.203120383 1.096322338 1.011376922 2.01E-15 0.95240684 0.043299399 0.278123807 0.243923224 0.006887453 0.334448109 6.26E-05 4.203120383 -1.011376922 down SIEAVHEDIR ddPTM_HeLa_Curcumin_4h_R1 4 SIEAVHEDIR 10 0 H7C312;H7BZ20;P23919-2;P23919 H7C312 DTYMK Thymidylate kinase 0 0 ;;; ;;; 111.27 0.005637 31613000 30262.8 24400 27340.6 26660.5 28827.3 38022.7 27443.7 26940.6 33218.6 27862.3 FALSE FALSE TRUE 27867.46745 26509.02728 28353.86669 26550.18592 28483.55328 30136.36342 28213.69636 35154.66492 29574.60269 28830.51285 0.966596314 0.919478173 0.983467302 0.92090578 0.987965543 1.045294046 0.978605428 1.219356211 1.025809109 1 14.81530888 SIFAS(ph)PESVTGK ddPTM_HeLa_Curcumin_4h_R1 2 SIFASPESVTGK 12 0 O75940 O75940 SMNDC1 Survival of motor neuron-related-splicing factor 30 1 0 SIFAS(0.774)PES(0.211)VT(0.015)GK;S(0.001)IFAS(0.923)PES(0.074)VT(0.001)GK ; 99.161 0.0097689 182102000 6450.3 6394.7 5885.2 5711.5 6245 10604.7 9608.9 3159.6 7186.6 5143 TRUE FALSE FALSE 5939.751949 6947.429374 6103.310689 5687.867326 6170.532454 8405.16568 9878.499873 4122.947495 6398.24796 5321.718867 1.116134109 1.305485981 1.146868304 1.068802669 1.159499892 1.579408062 1.856261129 0.774739816 1.202289734 1 12.37767658 -6.390536615 0.458071485 1.024760402 1.417732863 0.058121588 0.279755943 1.434315368 0.598601272 0.08859645 0.231795674 4.07E-07 6.390536615 0.392972461 GSDIDNPTLTVMDISPPSRS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 GSDIDNPTLTVMDISPPSRSPR 22 1 Q9Y2U5 Q9Y2U5 MAP3K2 Mitogen-activated protein kinase kinase kinase 2 1 0 GSDIDNPTLTVMDIS(0.001)PPS(0.251)RS(0.748)PR 83.167 0.0016192 28131000 2874.7 2374.6 2355 2458.7 2389.9 2769.6 1408.1 942.04 3188.2 2655.2 TRUE FALSE FALSE 2647.164462 2579.849843 2442.278372 2448.526551 2361.402003 2195.15374 1447.607496 1229.263659 2838.462436 2747.468002 0.963492372 0.93899177 0.888919678 0.891193837 0.859482986 0.79897336 0.526887845 0.447416916 1.033119379 1 11.42388696 -4.202633878 0.579774376 0.980771204 1.58E-13 0.952762816 0.04048132 0.478992949 0.103657107 0.006996069 0.318923126 6.27E-05 4.202633878 -0.980771204 down SILAKPSSS(ph)PDPR ddPTM_HeLa_Curcumin_4h_R1 1 SILAKPSSSPDPR 13 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 0 SILAKPS(0.009)S(0.033)S(0.957)PDPR 124.81 0.019707 41853000 1763.4 1219.3 1403.3 1598.8 1453.5 1203.7 1172.8 439.89 1330.2 986.76 TRUE FALSE FALSE 1623.825029 1324.690859 1455.307532 1592.184589 1436.167962 954.0390515 1205.705612 574.010436 1184.280388 1021.049837 1.590348454 1.297381197 1.425305093 1.55936031 1.406560102 0.934370701 1.180848935 0.562176708 1.159865411 1 9.995837569 -4.050563868 1.100215821 1.318285539 2.43E-12 0.560323552 0.199192531 1.885591706 1.34700124 0.038523113 3.206977639 8.90E-05 4.050563868 -1.318285539 SILKPSTPIPPQEGEEVGESS(ph)EEQDNAPK ddPTM_HeLa_Curcumin_4h_R1 2 SILKPSTPIPPQEGEEVGESSEEQDNAPK 29 1 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;A0A3B3IRI3;A0A3B3ISZ5;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 SILKPSTPIPPQEGEEVGES(0.421)S(0.579)EEQDNAPK;SILKPSTPIPPQEGEEVGES(0.417)S(0.583)EEQDNAPK ; 121.83 8.69E-09 17618000 6055.6 5211.7 4775.2 5285.9 5604.7 6965.6 5247 3069.8 6662.2 5691.1 TRUE FALSE FALSE 5576.29287 5662.176125 4952.173113 5264.028346 5537.867613 5520.856042 5394.216698 4005.767888 5931.373328 5888.865301 0.94692145 0.961505457 0.840938425 0.893895186 0.94039638 0.937507611 0.916002731 0.68022746 1.007218373 1 12.52377396 -3.728086034 1.427123571 0.955099165 1.34E-09 0.723864939 0.047307641 2.023550835 1.269774862 0.007711125 4.027800659 0.000187031 3.728086034 -0.955099164 SILPYPVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SILPYPVSPK 10 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 0 SILPYPVS(1)PK;SILPYPVS(1)PK ; 128.31 0.0031585 102385000 8656.8 5622.7 8480.2 9659.9 8531 11900.2 10503.2 5304.8 11054.9 8823.2 TRUE FALSE FALSE 7971.605145 6108.701134 8794.483672 9619.929893 8429.273397 9431.964377 10797.89152 6922.2091 9842.205128 9129.805543 0.873140738 0.669094331 0.96327174 1.053683986 0.923269763 1.033095867 1.182707723 0.758198963 1.078030094 1 13.15636842 -6.528040196 24.9890545 0.91324245 1.000444921 0.072354566 0.140590758 278.5145379 1348417.689 0.020970456 0.029716596 2.96E-07 6.528040196 0.087202471 SILVS(ph)PTGPSR ddPTM_HeLa_Curcumin_4h_R1 1 SILVSPTGPSR 11 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 0 SILVS(0.997)PT(0.003)GPSR 125.36 0.0035015 39065000 1744.3 1397.2 1349.1 1734 1556.3 2886.3 2204.9 1527.6 1944.6 1307.4 TRUE FALSE FALSE 1606.236814 1517.967742 1399.098833 1726.825167 1537.742139 2287.648845 2266.76356 1993.358208 1731.282245 1352.832053 1.18731428 1.122066659 1.034199944 1.276451991 1.136683697 1.691007276 1.675569081 1.473470564 1.279746619 1 10.40176703 -5.269871706 20.75669037 1.106011068 1.619571049 0.796411341 0.106311999 16.56134768 40767.83955 0.014912394 0.034026153 5.37E-06 5.269871706 0.513559981 SINEENGEVS(ph)EDQSQNK ddPTM_HeLa_Curcumin_4h_R1 2 SINEENGEVSEDQSQNK 17 0 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 0 SINEENGEVS(1)EDQSQNK;SINEENGEVS(1)EDQSQNK ; 199.61 2.20E-08 37137000 5026.3 4669.2 4817.9 5273.6 5134.3 5079.8 4012.6 3834.4 5262.2 4792.6 TRUE FALSE FALSE 4628.463051 5072.784842 4996.455612 5251.779241 5073.076826 4026.192219 4125.182757 5003.490909 4684.949825 4959.142493 0.93331923 1.022915726 1.007524107 1.059009546 1.022974604 0.811872662 0.831833883 1.008942759 0.944709661 1 12.27587496 -5.27128921 24.94883901 0.985124375 0.878978178 0.414086063 0.060808332 514.744515 1303807.316 0.00900305 0.02036321 5.35E-06 5.27128921 -0.106146197 SINHQIES(ph)PSER ddPTM_HeLa_Curcumin_4h_R1 2 SINHQIESPSER 12 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 SINHQIES(0.809)PS(0.191)ER;SINHQIES(0.802)PS(0.197)ER ; 134.04 0.0012386 22066000 2189.7 1998.93 2279.9 2418.4 2841.5 3991.3 2418.1 1541.64 2826.9 2086.4 TRUE FALSE FALSE 2016.382934 2171.708602 2364.3951 2408.393302 2807.616968 3163.459389 2485.945378 2011.678939 2516.796143 2158.902245 0.933985288 1.005931884 1.095183955 1.115563851 1.300483602 1.465309231 1.151485846 0.931806405 1.16577587 1 11.0760822 -6.433959768 1.68180311 0.969601505 1.219236005 0.202172742 0.142030808 0.26488016 1.480815608 0.021843114 0.036553215 3.68E-07 6.433959768 0.2496345 LDLGEDYPSGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 LDLGEDYPSGKK 12 1 O43143 O43143 DHX15 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 0 1 ; LDLGEDYPSGK(1)K;LDLGEDYPSGK(1)K 168.94 4.61E-07 4563600 2348.51 2013.02 2303.4 2350.93 2441 3055.8 2828.1 4084.8 2122.15 1671 FALSE TRUE FALSE 2162.622955 2187.016479 2388.76603 2341.202475 2411.892669 2421.992634 2907.448875 5330.236716 1889.355454 1729.067126 1.250745517 1.264853427 1.381534583 1.354026365 1.394909795 1.400751074 1.681513014 3.082723994 1.092702201 1 10.75577816 -1.578902302 0.833826763 1.170201382 200 0.948880803 0.12642332 35.24514597 0.296247136 0.025010476 13021.58002 0.026369245 1.578902302 198.8297986 up SIPAGAEPGEKGS(ph)AR ddPTM_HeLa_Curcumin_4h_R1 2 SIPAGAEPGEKGSAR 15 1 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 0 SIPAGAEPGEKGS(1)AR;SIPAGAEPGEKGS(1)AR ; 181.81 0.00045137 45052000 3993.4 2971.45 3319.8 3791.9 3674.6 7113.5 7337.6 2750.1 4289.7 2788.3 TRUE FALSE FALSE 3677.318176 3228.288897 3442.834708 3776.210123 3630.782795 5638.079914 7543.473308 3588.59283 3819.130642 2885.193217 1.274548323 1.118916015 1.193277001 1.308823998 1.258419288 1.954142925 2.614547013 1.243796363 1.323700132 1 11.49445222 -5.283703382 4.050042058 1.15362121 2.015824071 0.507244604 0.323958281 0.104432073 3.98068 0.04233734 0.104596666 5.20E-06 5.283703382 0.862202861 SIPTDNQIK ddPTM_HeLa_Curcumin_4h_R1 2 SIPTDNQIK 9 0 B4DLR8;H3BNV2;P15559-3;P15559-2;P15559 B4DLR8 NQO1 NAD(P)H dehydrogenase [quinone] 1 0 0 ; ; 134.05 0.00038856 9913600 7446.3 6612.7 6595.3 6798.8 7343 9514 7785.7 6701.1 7617.7 7740.6 FALSE FALSE TRUE 6856.917498 7184.272322 6839.72762 6770.668367 7255.439521 7540.689155 8004.145788 8744.234542 6782.057369 8009.585274 0.856088956 0.89695934 0.853942793 0.845320717 0.905844594 0.941458128 0.999320878 1.091721262 0.846742639 1 12.96751183 -4.459413806 1.711099655 0.913944298 1.115772044 0.614738603 0.049118702 0.467741322 1.781820519 0.009307119 0.135237111 3.47E-05 4.459413806 0.201827746 SIQADGLVWGS(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 SIQADGLVWGSSK 13 0 P24534 P24534 EEF1B2 Elongation factor 1-beta 1 0 SIQADGLVWGS(0.645)S(0.355)K 188.25 1.34E-05 12316000 2001.5 1534.5 1878.9 1910.5 1892.6 2474.5 1644.2 1394.5 2020.5 1622.5 TRUE FALSE FALSE 1843.079163 1667.135342 1948.533687 1902.594857 1870.031981 1961.260807 1690.331827 1819.676631 1798.856205 1678.881754 1.097801652 0.993003431 1.160614011 1.133251256 1.113855682 1.168194723 1.006820059 1.083862295 1.07146093 1 10.71328491 -9.359103656 0.4772719 0.973998774 1.100726867 0.096965663 0.058505192 1.815807509 0.525559994 0.111589374 0.01510327 4.37E-10 9.359103656 0.126728093 SIQADGLVWGSS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SIQADGLVWGSSK 13 0 P24534 P24534 EEF1B2 Elongation factor 1-beta 1 0 SIQADGLVWGS(0.068)S(0.932)K 143.64 0.00083333 18341000 2363.8 2188.8 2175.8 2122.2 2269.5 3150.2 2425.2 1394.1 2737.4 2251 TRUE FALSE FALSE 2176.702736 2377.990119 2256.437062 2113.418899 2242.437695 2496.81301 2493.244585 1819.154672 2437.114069 2329.222082 0.934519191 1.020937478 0.968751361 0.907349675 0.962741042 1.071951459 1.070419435 0.781013836 1.046321039 1 11.18563249 SIQADGLVWGSSK ddPTM_HeLa_Curcumin_4h_R1 1 SIQADGLVWGSSK 13 0 P24534 P24534 EEF1B2 Elongation factor 1-beta 0 0 186.51 3.68E-09 2093300 1973.5 1451.8 1619.8 1606 1669.5 1677.4 1429.1 1264.8 1752.5 1571.6 FALSE FALSE TRUE 1817.295393 1577.287123 1679.831213 1599.354798 1649.592303 1329.488332 1469.1967 1650.431698 1560.255135 1626.212983 1.117501466 0.969914236 1.032971222 0.983484214 1.014376542 0.817536415 0.903446667 1.014892708 0.95944083 1 10.6673005 -5.896684707 1.249508723 1.049816032 0.916788521 0.185084345 0.068324446 0.342931406 1.064530211 0.011269054 0.027578297 1.27E-06 5.896684707 -0.133027512 SIQDLTVTGTEPGQVSS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 SIQDLTVTGTEPGQVSSR 18 0 Q9UG54;O43318-4;O43318-3;O43318-2;O43318 Q9UG54 DKFZp586F0420;MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1 0 SIQDLTVT(0.003)GT(0.009)EPGQVS(0.224)S(0.765)R;SIQDLTVTGT(0.024)EPGQVS(0.205)S(0.77)R ; 242.9 5.40E-32 72208000 7738.5 6291.2 8053.3 8001.5 6845.6 5687.1 4494.5 2261.52 7130.3 7276.8 TRUE FALSE FALSE 7125.989559 6834.983295 8351.762382 7968.391913 6763.970691 4507.531353 4620.603574 2951.047037 6348.123929 7529.668258 0.946388249 0.907740296 1.109180657 1.058266001 0.898309256 0.598636115 0.613653008 0.391922584 0.843081489 1 12.87837059 -5.210785391 2.099497967 0.985844756 0.5009826 0.846670359 0.085356697 0.076183038 0.643519817 0.010784934 0.034562708 6.15E-06 5.210785391 -0.484862155 SIQEIQELDKDDES(ph)LRK ddPTM_HeLa_Curcumin_4h_R1 1 SIQEIQELDKDDESLRK 17 2 J3KTF8;J3QQX2;P52565;J3KRE2;J3KRY1;P52565-2;J3KS60 J3KTF8 ARHGDIA Rho GDP-dissociation inhibitor 1 1 0 SIQEIQELDKDDES(1)LRK 47.223 0.017765 14717000 2744 2666.2 3220.5 3238.2 3243.6 4114.4 3620.3 1018.9 3074.7 2559.8 TRUE FALSE FALSE 2526.809505 2896.654448 3339.854563 3224.801186 3204.922188 3261.027061 3721.875874 1329.55792 2737.413103 2648.752859 0.953961973 1.093591815 1.260915888 1.217479077 1.209974036 1.231155655 1.405142749 0.5019562 1.033472448 1 11.37109752 -7.086828686 4.339548457 0.978794739 1.162291487 0.063779928 0.227886435 0.342265376 11.55213794 0.034871243 0.043353826 8.19E-08 7.086828686 0.183496748 SIQEIQELDKDDESLR ddPTM_HeLa_Curcumin_4h_R1 2 SIQEIQELDKDDESLR 16 1 J3KTF8;J3QQX2;P52565;J3KRE2;J3KRY1;P52565-2;J3KS60 J3KTF8 ARHGDIA Rho GDP-dissociation inhibitor 1 0 0 ; ; 200 2.50E-08 110187000 6697.9 5825.5 5655.1 6262.6 6440.1 6998.2 5823.3 5921.9 7206 6184.1 FALSE FALSE TRUE 6167.754147 6329.030262 5864.682981 6236.687021 6363.306014 5546.694434 5986.686125 7727.460049 6415.519829 6398.997015 0.963862639 0.989065981 0.916500346 0.974635088 0.994422407 0.866806848 0.935566326 1.207604884 1.002582094 1 12.64363008 -4.256566444 24.88066867 0.968699152 1.207604989 0.756896643 0.041794093 187.8895751 959308.3793 0.005920395 0.065632109 5.54E-05 4.256566444 0.238905837 SIQEIQELDKDDESLRK ddPTM_HeLa_Curcumin_4h_R1 2 SIQEIQELDKDDESLRK 17 2 J3KTF8;J3QQX2;P52565;J3KRE2;J3KRY1;P52565-2;J3KS60 J3KTF8 ARHGDIA Rho GDP-dissociation inhibitor 1 0 0 ; ; 64.565 0.010295 158730000 4170.5 3426.9 3180.6 4072.4 3804.6 4643.1 3245.6 3421.4 4304.3 3774 FALSE FALSE TRUE 3840.400524 3723.105966 3298.475834 4055.549488 3759.23263 3680.068721 3336.662801 4464.56911 3832.129059 3905.146219 0.983420417 0.953384523 0.844648484 1.03851412 0.962635563 0.942363874 0.854427111 1.143252739 0.981302324 1 11.93116085 -7.423502278 3.521870394 0.993068492 0.956346158 0.016417534 0.080620256 0.653371214 14.52970817 0.01318279 0.014803881 3.77E-08 7.423502278 -0.036722334 SIQFVDWCPTGFK ddPTM_HeLa_Curcumin_4h_R1 5 SIQFVDWCPTGFK 13 0 P68363;P68363-2;P68366-2;P68366 P68363;P68366-2 TUBA1B;TUBA4A Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 0 ;;;; ;;;; 196.57 1.33E-32 15173730 4604.02 3991.38 5111.53 4208.13 4823.06 5987.42 3794 3956.81 3907.956 2877.9 FALSE FALSE TRUE 4239.606959 4336.377102 5300.967798 4190.717873 4765.54816 4745.5616 3900.449429 5163.223154 3479.263004 2977.906811 1.423686914 1.456182942 1.780098618 1.407269649 1.600301306 1.593589693 1.309795664 1.733843093 1.16835859 1 11.54008289 -8.658496865 0.550040898 0.972577674 1.560872677 0.621130239 0.142597642 0.372684158 0.216506942 0.105041521 0.034829681 2.20E-09 8.658496865 0.588295003 SSSSSGVPYS(ph)PAIPNK ddPTM_HeLa_Curcumin_4h_R1 3 SSSSSGVPYSPAIPNK 16 0 A0A0A0MRE1;B4DJ07;A0A0A0MSB8;Q9UPT5-4;Q9UPT5-2;Q9UPT5-5;Q9UPT5-1;Q9UPT5-6;Q9UPT5 A0A0A0MRE1 EXOC7 Exocyst complex component 7 1 0 S(0.006)SS(0.001)S(0.004)S(0.02)GVPY(0.33)S(0.639)PAIPNK;SSSSSGVPY(0.005)S(0.995)PAIPNK;SSSSSGVPY(0.041)S(0.959)PAIPNK ;; 127.07 0.00061821 88300000 27252.2 21327.4 23097.7 24866.9 23917.9 25345.6 17496.6 6248.6 26304.4 21704.9 TRUE FALSE FALSE 25095.15961 23170.84542 23953.72108 24764.00736 23632.69466 20088.63686 17987.50751 8153.769375 23418.87313 22459.14366 1.117369388 1.031688731 1.066546501 1.102624736 1.052252705 0.894452485 0.800899081 0.363048988 1.042732238 1 14.4550153 -4.202370987 1.179276799 1.059025153 5.70E-19 0.961590952 0.042164224 0.278319555 0.28854873 0.00778445 0.372699442 6.28E-05 4.202370987 -1.059025153 down (ac)MDLAAAAEPGAGS(ph)QHLEVRDEVAEK ddPTM_HeLa_Curcumin_4h_R1 3 MDLAAAAEPGAGSQHLEVRDEVAEK 25 1 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 1 0 MDLAAAAEPGAGS(1)QHLEVRDEVAEK;MDLAAAAEPGAGS(1)QHLEVRDEVAEK;MDLAAAAEPGAGS(1)QHLEVRDEVAEK ;; 55.02 5.03E-06 104330000 6937.4 5243.3 5777.1 6493.4 6063.1 10585 9485.1 15955.2 8545.1 7241.6 TRUE FALSE FALSE 6388.29747 5696.507488 5991.204408 6466.532031 5990.801492 8389.551682 9751.226378 20819.86703 7607.723909 7493.245061 0.852540844 0.76021903 0.799547374 0.862981523 0.799493603 1.119615282 1.301335576 2.778484737 1.015277606 1 12.87137492 -4.000991735 1.505876579 0.895791343 4.673914517 0.970325171 0.098664774 0.269683355 0.338293625 0.01545506 1.82159187 9.98E-05 4.000991735 3.778123174 up SIS(ph)CGPSSR ddPTM_HeLa_Curcumin_4h_R1 2 SISCGPSSR 9 0 Q5VU43-13;Q5VU43-2 Q5VU43-13 PDE4DIP Myomegalin 1 0 S(0.049)IS(0.951)CGPSSR;S(0.019)IS(0.981)CGPSSR ; 136.5 0.0028974 67433000 5402.6 4100.2 5524.9 5711.2 5141.8 5049.6 3279.7 5941.6 4768.4 5079.6 TRUE FALSE FALSE 4974.978509 4454.603018 5729.657654 5687.568568 5080.487393 4002.256039 3371.719555 7753.166488 4245.31845 5256.115722 0.946512362 0.847508551 1.090093513 1.082085873 0.966585909 0.761447474 0.641485031 1.475075302 0.807691207 1 12.35978132 -4.237468104 24.288016 0.949209387 1.47507621 0.578024505 0.141673113 2759.500885 2795901.723 0.018936993 1.514282636 5.79E-05 4.237468104 0.525866823 SIS(ph)KDSLASNIVNLTPQNQPHPTATK ddPTM_HeLa_Curcumin_4h_R1 1 SISKDSLASNIVNLTPQNQPHPTATK 26 1 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 0 S(0.242)IS(0.699)KDS(0.036)LAS(0.024)NIVNLTPQNQPHPTATK 69.756 0.00026521 17850000 1138.3 1195.7 1050.5 899.34 1813.5 2905.5 1413 1626.3 1995.5 1090.8 TRUE FALSE FALSE 1048.202354 1299.05098 1089.432454 895.6187694 1791.875197 2302.866548 1452.644977 2122.151383 1776.598642 1128.705219 0.928676803 1.150921391 0.965205473 0.793492184 1.587549315 2.040272792 1.287001205 1.880164411 1.574014732 1 10.14045303 -5.680811368 5.749513286 0.970503178 1.707023363 0.545185931 0.274520825 0.067705861 3.687561308 0.025941359 0.052211268 2.09E-06 5.680811368 0.736520185 SIS(ph)LGDSEGPIVATLAQPLR ddPTM_HeLa_Curcumin_4h_R1 3 SISLGDSEGPIVATLAQPLR 20 0 O43379;O43379-4 O43379 WDR62 WD repeat-containing protein 62 1 0 S(0.004)IS(0.996)LGDSEGPIVATLAQPLR;S(0.007)IS(0.977)LGDS(0.016)EGPIVATLAQPLR;S(0.044)IS(0.951)LGDS(0.005)EGPIVATLAQPLR ;; 171.52 1.98E-06 82654400 1711.73 1373.25 1822.44 1874.38 1714.13 2364.53 1802.74 1116.94 1800.36 1416.06 TRUE FALSE FALSE 1576.244764 1491.947611 1889.98123 1866.624312 1693.690119 1874.099824 1853.320033 1457.489864 1602.865012 1465.26798 1.075738217 1.018208022 1.289853635 1.273913262 1.155891033 1.279015068 1.264833504 0.994691677 1.093905712 1 10.51694882 -6.772761632 24.99891747 1.035447784 1.215829428 0.457954681 0.086218378 125.6890202 277513.9531 0.013241517 0.01748964 1.69E-07 6.772761632 0.180381644 SCPSFS(ph)ASSEGTR ddPTM_HeLa_Curcumin_4h_R1 2 SCPSFSASSEGTR 13 0 D6RG38;D6RCP9;D6RFG8;P27707 D6RG38 DCK Deoxycytidine kinase 1 0 SCPS(0.202)FS(0.575)AS(0.168)S(0.055)EGTR;S(0.001)CPS(0.174)FS(0.636)AS(0.185)S(0.004)EGTR ; 212.1 6.30E-10 25607000 1878.27 1604.02 1753.33 1873.35 1637.82 2431.2 2178.03 2959.3 2241.77 1585.84 TRUE FALSE FALSE 1729.602948 1742.664341 1818.309952 1865.598574 1618.290066 1926.941715 2239.13966 3861.576947 1995.85344 1640.947822 1.054026779 1.061986444 1.108085174 1.136903044 0.986192275 1.174285793 1.364540438 2.353260046 1.216280867 1 10.68031365 -3.998226249 1.438886055 1.04146704 3.687635387 0.960817165 0.076042248 0.208472662 0.237158612 0.008117472 0.946399964 0.000100409 3.998226249 2.646168347 up SIS(ph)LTRPGSSSLSSGPNSILCR ddPTM_HeLa_Curcumin_4h_R1 1 SISLTRPGSSSLSSGPNSILCR 22 1 A0A087WZ32;A0A087X038;A8K727;Q9HB19 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 0 S(0.23)IS(0.741)LT(0.029)RPGSSSLSSGPNSILCR 87.92 0.00019888 126850000 279.12 243.69 278.69 397.8 253.97 282.11 191.39 410.43 349.9 415.67 TRUE FALSE FALSE 257.0273575 264.7534777 289.0184966 396.154009 250.9415736 223.597206 196.7598883 535.5682176 311.5168454 430.1145016 0.597578916 0.615541854 0.671957108 0.921043135 0.583429698 0.519855074 0.457459322 1.245175914 0.724264921 1 8.748576963 -9.35921893 1.04154759 1.00309496 0.680889555 0.013075583 0.232692555 0.614901293 1.175644087 0.147529344 0.036915452 4.37E-10 9.35921893 -0.322205405 SIS(ph)NEGLTLNNSHVSK ddPTM_HeLa_Curcumin_4h_R1 2 SISNEGLTLNNSHVSK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 0 S(0.153)IS(0.847)NEGLTLNNSHVSK;S(0.008)IS(0.992)NEGLTLNNSHVSK ; 174.04 2.87E-05 61472000 8866.8 5774.1 6737 7290.8 10995.7 23372.7 11276.1 11939.9 10189.6 7303.1 TRUE FALSE FALSE 8164.983424 6273.187475 6986.679146 7260.632601 10864.58346 18524.93856 11592.47702 15580.32055 9071.826373 7556.882181 1.080469859 0.830129056 0.9245452 0.96079738 1.437707139 2.451399679 1.53402908 2.061739243 1.20047212 1 12.88357541 -5.520910577 4.468530315 1.010545937 1.971562393 0.798289916 0.228189043 0.057860317 2.90925015 0.029309033 0.063585965 3.01E-06 5.520910577 0.961016456 SIS(ph)NPPGSNLR ddPTM_HeLa_Curcumin_4h_R1 1 SISNPPGSNLR 11 0 F5GWT4;Q9H4A3-2;Q9H4A3;Q9H4A3-5;Q9H4A3-6;Q9H4A3-7;Q9H4A3-4 F5GWT4 WNK1 Serine/threonine-protein kinase WNK1 1 0 S(0.013)IS(0.986)NPPGSNLR 97.957 0.012337 8150800 2156.4 1515.3 1740.9 2061.5 2090.7 2266.8 1759.3 1466 1846.9 1573.5 TRUE FALSE FALSE 1985.718665 1646.27578 1805.419285 2052.970059 2065.769768 1796.640128 1808.661223 1912.976651 1644.299691 1628.179008 1.219594808 1.011114731 1.10885798 1.260899477 1.268760841 1.10346597 1.110849123 1.174917894 1.009901051 1 10.66904361 -9.473143982 1.059931058 0.994420459 1.161236234 0.396197671 0.075060206 0.496672759 0.942105805 0.0653516 0.013999979 3.36E-10 9.473143982 0.166815775 SIS(ph)PEVSASRR ddPTM_HeLa_Curcumin_4h_R1 2 SISPEVSASRR 11 1 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 0 S(0.285)IS(0.715)PEVSASRR;S(0.2)IS(0.8)PEVSASRR ; 92.295 0.0074015 25674200 5066.4 4006.2 4412.4 4979.6 3901.4 4866.3 3156.9 2031.7 6493.5 4967.4 TRUE FALSE FALSE 4665.389094 4352.478077 4575.927426 4958.995735 3854.878353 3856.974525 3245.474118 2651.155977 5781.179296 5140.01678 0.907660285 0.846782854 0.890255348 0.964782013 0.749973885 0.750381699 0.631413137 0.515787417 1.124739382 1 12.32755735 -3.785704006 0.389417759 0.967168535 9.13E-15 0.834369938 0.069796426 1.736895197 0.137389811 0.014199383 0.844974008 0.000163793 3.785704006 -0.967168535 SIS(ph)VGENLGLVAEPQAHAPIR ddPTM_HeLa_Curcumin_4h_R1 1 SISVGENLGLVAEPQAHAPIR 21 0 O60336-4;O60336-3;O60336-6;O60336 O60336-4 MAPKBP1 Mitogen-activated protein kinase-binding protein 1 1 0 S(0.05)IS(0.95)VGENLGLVAEPQAHAPIR 144.43 1.35E-05 10121000 1127.3 752.03 836.41 801.63 985.36 1742.8 1232.4 976.59 832.76 1011.9 TRUE FALSE FALSE 1038.073015 817.0321222 867.4080904 798.3130675 973.6102256 1381.323635 1266.977827 1274.347795 741.4083115 1047.06345 0.991413668 0.78030813 0.828419797 0.76243046 0.929848354 1.319235845 1.210029657 1.21706836 0.708083461 1 10.03213315 -5.268511858 24.69089868 0.94460816 1.244903128 0.653066322 0.119423636 232.0454055 810100.425 0.016231489 0.037034018 5.39E-06 5.268511858 0.300294968 SISASKAS(ph)PPGDLQNPK ddPTM_HeLa_Curcumin_4h_R1 1 SISASKASPPGDLQNPK 17 1 O00273 O00273 DFFA DNA fragmentation factor subunit alpha 1 0 SISAS(0.003)KAS(0.997)PPGDLQNPK 102.67 0.00073337 282630000 2898.3 2368.4 2290.3 2692.9 2759.4 3056.3 2632.1 1770.9 2885.8 2400.3 TRUE FALSE FALSE 2668.896497 2573.113943 2375.180533 2681.757493 2726.495957 2422.388928 2705.949642 2310.839258 2569.23496 2483.710246 1.074560328 1.035996025 0.956303392 1.079738467 1.097751222 0.975310599 1.089478793 0.930398085 1.034434256 1 11.27828116 -4.241649147 24.05629749 1.036515351 0.930397919 0.327784388 0.046247778 2660.427476 3233837.927 0.006458963 0.319402085 5.73E-05 4.241649147 -0.106117432 SISASKAS(ph)PPGDLQNPKR ddPTM_HeLa_Curcumin_4h_R1 1 SISASKASPPGDLQNPKR 18 2 O00273 O00273 DFFA DNA fragmentation factor subunit alpha 1 0 SIS(0.001)AS(0.003)KAS(0.996)PPGDLQNPKR 108.25 0.00061624 24276000 1975 1242.1 1215.3 1376.4 1104.4 1721 1219.2 1034.2 2052.5 1533.6 TRUE FALSE FALSE 1818.676666 1349.461589 1260.340087 1370.704821 1091.230751 1364.0452 1253.407471 1349.522819 1827.345885 1586.892486 1.146061679 0.850379973 0.794218952 0.86376666 0.687652605 0.859570017 0.789850278 0.850418558 1.151524695 1 10.63198867 -7.157668935 5.225131794 1.068648126 0.807853785 0.806160777 0.063814902 0.07910905 3.269395805 0.011497149 0.014130034 6.96E-08 7.157668935 -0.260794341 QLLT(ph)LSSELSQAR ddPTM_HeLa_Curcumin_4h_R1 1 QLLTLSSELSQAR 13 0 E7EQR4;P15311 E7EQR4 EZR Ezrin 1 0 QLLT(0.619)LS(0.29)S(0.091)ELSQAR 115.09 0.0085797 3564000 541.46 352.61 380.27 456.54 580.19 621 681.03 613.58 579.4 366.05 TRUE FALSE FALSE 498.6028697 383.0880372 394.3631407 454.6509584 573.2716132 492.1975999 700.1378689 800.6577174 515.8412696 378.7702103 1.316372978 1.011399595 1.041167257 1.20033452 1.513507656 1.299462277 1.848450195 2.113834974 1.361884477 1 8.565179059 -3.995978883 0.656228366 1.129538219 3.163920607 0.813464996 0.150429433 1.22584998 0.287597808 0.026800662 2.014738908 0.00010093 3.995978883 2.034382389 up SISLYYTGEK ddPTM_HeLa_Curcumin_4h_R1 1 SISLYYTGEK 10 0 P19338;H7BY16 P19338 NCL Nucleolin 0 0 205.83 1.87E-26 14275000 4119.7 2679.7 3728.5 3397.2 3584.6 4593.4 4175.8 4215.5 3988.9 3458.3 FALSE FALSE TRUE 3793.621398 2911.321327 3866.68149 3383.143287 3541.855986 3640.677062 4292.961709 5500.786544 3551.32765 3578.475668 1.060122172 0.813564657 1.080538712 0.94541464 0.989766681 1.017382092 1.199662121 1.537187075 0.992413525 1 11.80512945 -4.322054553 1.932129781 1.007112795 1.659453877 0.849454773 0.071151705 0.188170174 0.805544711 0.009983165 0.208551228 4.76E-05 4.322054553 0.652341082 SISS(ph)PSVSSETMDKPVDLSTRK ddPTM_HeLa_Curcumin_4h_R1 1 SISSPSVSSETMDKPVDLSTRK 22 2 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 S(0.001)IS(0.096)S(0.443)PS(0.304)VS(0.067)S(0.067)ET(0.021)MDKPVDLSTRK 82.177 0.00054212 21939000 4259.7 3243.7 2926.2 3365.4 2648.6 4664 3700.3 2767.2 3952.8 3338.2 TRUE FALSE FALSE 3922.54025 3524.070974 3034.647546 3351.474867 2617.017175 3696.633826 3804.120459 3610.906541 3519.187729 3454.202202 1.135585012 1.020227181 0.878537899 0.970260185 0.757632884 1.070184549 1.101302193 1.04536629 1.01881347 1 11.75413682 -6.997723202 24.85469042 1.064756776 0.969499867 0.117568756 0.098867647 100.7146019 1099431.723 0.017432589 0.0228295 1.01E-07 6.997723202 -0.09525691 SISSPSVSSET(ph)MDKPVDLSTR ddPTM_HeLa_Curcumin_4h_R1 1 SISSPSVSSETMDKPVDLSTR 21 1 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 SIS(0.001)S(0.004)PS(0.012)VS(0.147)S(0.147)ET(0.689)MDKPVDLSTR 75.743 0.0010655 41466000 4273.1 3688.8 4158.6 4368.8 4586.5 5710.5 5083.1 3648.1 4507.9 3523.3 TRUE FALSE FALSE 3934.879626 4007.643435 4312.721374 4350.723063 4531.808983 4526.077929 5225.718106 4760.388896 4013.394648 3645.734413 1.079310553 1.099269168 1.182949959 1.193373562 1.243044191 1.241472202 1.433378714 1.305742097 1.100846687 1 11.83199375 -5.589643141 0.338422741 1.000923913 1.477861759 0.81468715 0.051413715 0.581579795 0.091769982 0.017978002 0.103909763 2.57E-06 5.589643141 0.476937846 RSS(ph)ITEPEGPNGPNIQK ddPTM_HeLa_Curcumin_4h_R1 1 RSSITEPEGPNGPNIQK 17 1 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 0 RS(0.008)S(0.663)IT(0.329)EPEGPNGPNIQK 171.87 8.07E-05 22152000 1973 1511.9 1686.9 2117.9 1844.8 2341.2 1569.5 770.11 2276.2 1945.6 TRUE FALSE FALSE 1816.834968 1642.581899 1749.417998 2109.136691 1822.801965 1855.608729 1613.535946 1004.912994 2026.506555 2013.209455 0.902457001 0.815902138 0.868969691 1.04764891 0.905420924 0.921716677 0.801474453 0.499159683 1.006604926 1 10.97528156 -4.201862081 1.657369382 0.940113004 0.294019227 0.802895795 0.065364992 0.386639908 0.900325365 0.010028671 0.41579053 6.28E-05 4.201862081 -0.646093777 down SIST(ph)SGPLDKEDTGR ddPTM_HeLa_Curcumin_4h_R1 1 SISTSGPLDKEDTGR 15 1 A0A0U1RR27;Q7Z401;Q7Z401-2 A0A0U1RR27 DENND4A C-myc promoter-binding protein 1 0 S(0.028)IS(0.086)T(0.443)S(0.443)GPLDKEDTGR 82.121 0.011544 10408000 1378.6 1160.5 1307.7 1469.1 1195.6 1190.1 1282.1 1389.7 1164.7 1104 TRUE FALSE FALSE 1269.482355 1260.808449 1356.164512 1463.021253 1181.343251 943.2598448 1318.072275 1813.413133 1036.935324 1142.363918 1.111276657 1.103683712 1.187156292 1.280696309 1.034121642 0.825708717 1.153811193 1.587421578 0.907710151 1 10.1578066 -4.287566066 4.090648674 1.06762965 1.61978224 0.618485325 0.124110551 0.099878483 3.484055807 0.01654227 0.153535401 5.16E-05 4.287566066 0.552152589 SIGS(ph)PESTPK ddPTM_HeLa_Curcumin_4h_R1 2 SIGSPESTPK 10 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 S(0.452)IGS(0.54)PES(0.001)T(0.007)PK;S(0.033)IGS(0.958)PES(0.004)T(0.004)PK ; 138.99 0.0016479 106689000 16014.8 13485.4 13716.5 14402.2 13994.8 16364.2 11549.7 3470.6 17210.5 14690.4 TRUE FALSE FALSE 14747.21168 14651.01789 14224.84556 14342.60751 13827.92115 12970.08046 11873.7535 4528.769963 15322.55121 15200.89031 0.97015447 0.963826302 0.935790291 0.943537334 0.909678372 0.85324479 0.781122241 0.297927942 1.008003538 1 13.8918682 -4.201130876 1.329404067 0.971699168 1.44E-19 0.962642607 0.038723777 0.201988643 0.276570188 0.005923062 0.274163932 6.29E-05 4.201130876 -0.971699168 down SITS(ph)TPLSGK ddPTM_HeLa_Curcumin_4h_R1 3 SITSTPLSGK 10 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3 RAI14 Ankycorbin 1 0 S(0.01)IT(0.069)S(0.861)T(0.061)PLSGK;S(0.113)IT(0.183)S(0.704)TPLS(0.001)GK;SIT(0.001)S(0.588)T(0.411)PLSGK ;; 205.07 8.45E-07 122347000 19758 17975.3 17448.4 17714.2 19141 29570.1 29767.6 20067.2 23302.7 19184.8 TRUE FALSE FALSE 18194.13345 19529.00484 18095.05305 17640.90333 18912.75608 23436.92794 30602.79874 26185.5969 20746.45211 19851.47037 0.91651314 0.983756088 0.911522054 0.88864467 0.95271311 1.180614206 1.541588515 1.319075938 1.045083902 1 14.27695825 -5.02218445 3.214928977 0.952283714 1.428527577 0.883043241 0.068806384 0.048179323 1.01542493 0.008803524 0.027826188 9.50E-06 5.02218445 0.476243863 SITST(ph)PLSGK ddPTM_HeLa_Curcumin_4h_R1 2 SITSTPLSGK 10 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3 RAI14 Ankycorbin 1 0 SITS(0.036)T(0.964)PLSGK;SIT(0.002)S(0.085)T(0.913)PLSGK ; 177.44 0.0010423 55299000 9143.7 7989.3 7679.2 7518.6 8854.6 13546.3 13765 10302 10223.5 9054.7 TRUE FALSE FALSE 8419.966497 8679.859492 7963.797907 7487.490025 8749.014678 10736.64468 14151.20885 13443.03238 9102.007628 9369.350151 0.898671344 0.926409981 0.84998402 0.799147209 0.933790982 1.145932696 1.510372505 1.434788129 0.971466268 1 13.19373327 -4.949882725 2.786168204 0.928975501 1.478439851 0.929798217 0.061135541 0.056074135 0.869958402 0.010460703 0.037602737 1.12E-05 4.949882725 0.54946435 SIVEGIIEEEEEDEEGSESISKR ddPTM_HeLa_Curcumin_4h_R1 2 SIVEGIIEEEEEDEEGSESISKR 23 1 Q9Y570-4;Q9Y570;Q9Y570-2 Q9Y570-4 PPME1 Protein phosphatase methylesterase 1 0 0 ; ; 227.64 1.76E-29 6585700 1560.19 1420.21 1416.31 1899.1 1739.12 1896.72 1606.99 1532.71 1944.33 1676.16 FALSE FALSE TRUE 1436.699315 1542.966624 1468.799695 1891.242027 1718.38213 1503.318892 1652.077814 2000.026223 1731.041863 1734.406435 0.828352159 0.88962229 0.84686015 1.09042609 0.990760928 0.86676275 0.952532106 1.153147372 0.998060102 1 10.7602263 -6.2734644 24.94411987 0.90930474 0.998385755 0.227844347 0.088798137 1025.365785 2126966.875 0.01504615 0.02309696 5.33E-07 6.2734644 0.089081015 SIVPS(ph)SPQPQR ddPTM_HeLa_Curcumin_4h_R1 1 SIVPSSPQPQR 11 0 H7C5K2;H7C5C6;H7C5A5;A0A1X7SBY3;H0Y860;Q9P246-3;Q9P246;Q9P246-2 H7C5K2 STIM2 Stromal interaction molecule 2 1 0 SIVPS(0.5)S(0.5)PQPQR 105.66 0.0083146 5658700 2559.4 2293 2391.2 2802.6 2293 2177.8 1372 1214.8 3530.3 2415.1 TRUE FALSE FALSE 2356.820789 2491.196703 2479.819976 2791.003584 2265.657473 1726.099731 1410.494627 1585.186928 3143.034922 2499.024545 0.943096295 0.996867641 0.992315174 1.116837203 0.906616734 0.690709395 0.564418077 0.634322272 1.257704703 1 11.28714936 -5.242320049 2.816503712 0.985751554 0.60434663 0.772579435 0.098972168 0.053955008 0.849958656 0.007436676 0.020696376 5.72E-06 5.242320049 -0.381404924 SIYDDISS(ph)PGLGST(ph)PLTSR ddPTM_HeLa_Curcumin_4h_R1 2 SIYDDISSPGLGSTPLTSR 19 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4 Q8NFH5-2 NUP35 Nucleoporin NUP53 2 0 SIYDDIS(0.407)S(0.593)PGLGS(0.288)T(0.711)PLTSR;S(0.009)IYDDIS(0.385)S(0.606)PGLGS(0.32)T(0.679)PLT(0.001)SR ; 186.17 4.01E-07 27766000 5555.2 5244.3 6058.2 5599.5 5762.5 12138 12207.2 6504.5 6701.1 4387.2 TRUE FALSE FALSE 5115.500058 5697.593924 6282.722221 5576.330753 5693.785951 9620.441977 12549.70118 8487.692107 5966.006095 4539.654873 1.126847789 1.255072045 1.383964728 1.228360064 1.25423322 2.119201183 2.764461513 1.869677838 1.314198163 1 12.14836691 -5.243654701 3.232291091 1.118601168 2.345259059 0.794905878 0.237071929 0.066156521 1.425366268 0.032105118 0.086105397 5.71E-06 5.243654701 1.226657891 SIYDDISSPGLGS(ph)TPLTSR ddPTM_HeLa_Curcumin_4h_R1 2 SIYDDISSPGLGSTPLTSR 19 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 0 SIYDDIS(0.002)S(0.014)PGLGS(0.823)T(0.16)PLT(0.001)SR;SIYDDIS(0.143)S(0.369)PGLGS(0.481)T(0.007)PLTSR ; 176.42 4.60E-07 29525000 6050.7 5727.9 6425.8 6135.1 6671.7 9282 7711.5 3308.2 7454.4 6021.3 TRUE FALSE FALSE 5571.78071 6222.994153 6663.945801 6109.714582 6592.144335 7356.80857 7927.863936 4316.854951 6636.67097 6230.539727 0.89426935 0.998788937 1.069561562 0.980607596 1.058037445 1.180765855 1.272420093 0.692854093 1.065183959 1 12.60514143 -6.962198895 4.4768299 0.949779747 1.056460525 0.00667593 0.148071442 0.349006786 15.96550075 0.022570042 0.029536189 1.09E-07 6.962198895 0.106680778 SIYFSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SIYFSSPK 8 0 A2IDA3;P29372-5;P29372-4;P29372-2;P29372 A2IDA3 MPG DNA-3-methyladenine glycosylase 1 0 SIYFS(0.018)S(0.982)PK 101.9 0.013943 30927000 4103.5 3522.6 3714.8 3841.1 3756.2 6066.9 5950.5 1664 5014.5 3228.4 TRUE FALSE FALSE 3778.703645 3827.077848 3852.473756 3825.206546 3711.409768 4808.556552 6117.455015 2171.34594 4464.421896 3340.58666 1.131149714 1.145630465 1.153232695 1.145070293 1.111005385 1.439434759 1.831251705 0.649989406 1.336418525 1 11.70588577 -5.321343987 6.718967719 1.085426036 1.358846189 0.024622793 0.285798472 0.293503945 27.4150781 0.035698217 0.080744391 4.77E-06 5.321343987 0.273420152 SIYGEKFEDENFILK ddPTM_HeLa_Curcumin_4h_R1 5 SIYGEKFEDENFILK 15 1 P62937;F8WE65;C9J5S7;P62937-2 P62937 PPIA "Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase" 0 0 ;;;; ;;;; 171.73 4.99E-05 532595200 13917.3 11699.4 16100 16962.9 11686.4 11507.72 9633.6 6960.24 6711.41 4528.4 FALSE FALSE TRUE 12815.73102 12710.644 16696.68016 16892.71201 11547.04731 9120.889153 9903.892888 9082.385135 5975.185114 4685.761563 2.735036951 2.712610071 3.563279936 3.60511558 2.464284014 1.946511582 2.113614352 1.938294344 1.275179079 1 12.19406783 -5.207043523 24.5255086 2.214376385 2.010887517 0 0.819282796 1835.067903 827373.169 0.148548593 0.378725874 6.21E-06 5.207043523 -0.203488867 SIYYITGESK ddPTM_HeLa_Curcumin_4h_R1 2 SIYYITGESK 10 0 P08238;Q58FF8 P08238 HSP90AB1;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2 0 0 ; ; 150.61 3.97E-06 45876000 11039.9 8398.4 9759.4 8714.8 9068.5 10132 8880.6 9329.8 9436.4 8393.8 FALSE FALSE TRUE 10166.08027 9124.320273 10121.09195 8678.740467 8960.36406 8030.508989 9129.765735 12174.41307 8401.250529 8685.483925 1.170467916 1.050525262 1.165288202 0.999223594 1.031648223 0.924589701 1.051152223 1.401696575 0.967274892 1 13.08439052 -4.259981186 24.72359568 1.065116315 1.401696703 0.649157924 0.077822899 60.06565847 1018288.601 0.011810976 0.099512581 5.50E-05 4.259981186 0.336580388 SK(ac)FDEMAK ddPTM_HeLa_Curcumin_4h_R1 1 SKFDEMAK 8 1 O15347;E9PES6;E7ES08;E7EQU1 O15347 HMGB3 High mobility group protein B3 0 1 SK(1)FDEMAK 93.111 0.01937 2134400 1694.9 1441 1575.1 1320.6 1970.6 1881.4 1768.2 1897.3 2175.1 1837.3 FALSE TRUE FALSE 1560.746877 1565.553619 1633.474592 1315.135707 1947.101882 1491.176432 1817.810933 2475.778036 1936.496972 1901.146038 0.820950545 0.823478885 0.859205216 0.691759434 1.024172706 0.784356595 0.956165858 1.30225558 1.018594539 1 10.89265364 -4.282233539 3.638600122 0.887446626 1.339915308 0.59835941 0.103567635 0.136008943 3.282669342 0.014497099 0.160985286 5.22E-05 4.282233539 0.452468682 SK(ac)IPNEHK(ac)KPAEVFR ddPTM_HeLa_Curcumin_4h_R1 2 SKIPNEHKKPAEVFR 15 3 Q92613;F2Z2B6;F2Z3N8 Q92613 JADE3 Protein Jade-3 0 2 ; SK(1)IPNEHK(0.997)K(0.003)PAEVFR;SK(1)IPNEHK(0.744)K(0.256)PAEVFR 89.136 0.0017513 20217500 6409.4 5903.2 5366.6 5760.9 7394.9 8232 5940.6 3699 6974.8 5417.9 FALSE TRUE FALSE 5902.089227 6413.446304 5565.490917 5737.062922 7306.720647 6524.590406 6107.277248 4826.808072 6209.68189 5606.171622 1.052784257 1.143997497 0.992743586 1.023347716 1.303335171 1.163822809 1.089384639 0.860981147 1.107651051 1 12.45280019 -8.068359593 0.697364871 1.005374068 1.091804733 0 0.114589206 1.208548399 1.303828501 0.043789565 0.028903865 8.54E-09 8.068359593 0.086430665 SK(ac)QPLQVTK ddPTM_HeLa_Curcumin_4h_R1 2 SKQPLQVTK 9 1 F8W126;Q96EZ8-3;Q96EZ8;Q96EZ8-2;F8W0I9;F8VVA6;F8VP44 F8W126 MCRS1 Microspherule protein 1 0 1 ; SK(1)QPLQVTK;SK(1)QPLQVTK 114.89 0.0019887 7929000 9423.3 8239.6 8485.8 9423.1 8893.8 6429.4 6761.7 5625 9297.3 7606.5 FALSE TRUE FALSE 8677.435862 8951.794309 8800.291213 9384.109709 8787.747244 5095.869966 6951.415104 7340.036606 8277.409451 7870.825309 1.102481064 1.137338711 1.118090018 1.192265022 1.116496288 0.647437818 0.883187573 0.93256251 1.051657117 1 12.9422992 -5.283496728 24.99689313 1.076633142 0.827275111 0.685714533 0.086070504 389.263573 441139.4813 0.013495829 0.030199293 5.21E-06 5.283496728 -0.249358031 SKAEEWGVQYVETSAK ddPTM_HeLa_Curcumin_4h_R1 1 SKAEEWGVQYVETSAK 16 1 C9J6B1;P11234;P11234-3;P11234-2 C9J6B1 RALB Ras-related protein Ral-B 0 0 39.033 0.018606 11046000 3551.9 2756.7 2824.8 2959.4 3109.1 3830.9 2723.8 2323.3 3702.6 3181.1 FALSE FALSE TRUE 3270.763367 2994.976864 2929.489573 2947.154787 3072.026013 3036.328157 2800.222497 3031.663475 3296.434043 3291.642988 0.993656778 0.909872934 0.889977918 0.895344604 0.933280439 0.922435443 0.850706625 0.921018314 1.001455521 1 11.68459215 -7.250087994 4.482485836 0.997342049 0.901704589 0.805292732 0.021468173 0.05880923 3.086662251 0.003569511 0.004255186 5.62E-08 7.250087994 -0.09563746 SKDEEEDEES(ph)DDADDTPILKPVSLLR ddPTM_HeLa_Curcumin_4h_R1 1 SKDEEEDEESDDADDTPILKPVSLLR 26 2 A0A3B3ITI3;A0A3B3IS53;A0A3F2YNX6;Q92794 A0A3B3ITI3 KAT6A Histone acetyltransferase KAT6A 1 0 SKDEEEDEES(1)DDADDTPILKPVSLLR 99.964 2.37E-06 16482000 668.08 458.34 395.13 409.65 419.29 535.5 322.76 197.99 611.05 386.57 TRUE FALSE FALSE 615.200763 497.9568673 409.7738654 407.9549768 414.2902406 424.4312637 331.8157769 258.3562396 544.0193438 400.0032787 1.537989301 1.244881964 1.024426266 1.019879082 1.035717112 1.061069462 0.829532643 0.645885305 1.360037211 1 8.643868015 -4.459145538 0.575278526 1.242784474 0.369060476 0.612844805 0.15008333 2.167709592 0.556216794 0.042099665 1.200632174 3.47E-05 4.459145538 -0.873723998 SKDHFGLEGDEESTMLEDSVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SKDHFGLEGDEESTMLEDSVSPK 23 1 Q9Y490 Q9Y490 TLN1 Talin-1 1 0 SKDHFGLEGDEESTMLEDS(0.016)VS(0.983)PK;SKDHFGLEGDEES(0.002)T(0.007)MLEDS(0.034)VS(0.956)PK ; 58.319 0.0031144 222587000 4118.1 3758.4 3106.12 3781.8 4824 7496.8 4070.8 2677.53 5871.9 3852.8 TRUE FALSE FALSE 3792.14804 4083.259349 3221.23554 3766.151914 4766.476951 5941.879174 4185.015692 3493.896571 5227.767261 3986.684513 0.951203444 1.024224349 0.807998609 0.944682706 1.195599234 1.490431248 1.049748401 0.876391538 1.311306988 1 11.96097373 -5.762497363 24.99951532 0.964262532 1.169763658 0.10062104 0.188215522 27.7155786 654926.0712 0.02254326 0.042618318 1.73E-06 5.762497363 0.205501126 TYSAPAINAIQGGSFES(ph)PKK ddPTM_HeLa_Curcumin_4h_R1 1 TYSAPAINAIQGGSFESPKK 20 1 Q9H4L5-5;Q9H4L5;Q9H4L5-7;Q9H4L5-3 Q9H4L5-5 OSBPL3 Oxysterol-binding protein-related protein 3 1 0 TYSAPAINAIQGGS(0.005)FES(0.995)PKK 153.24 8.90E-06 57327000 1378.6 1310.2 1266.7 1122.3 1204.7 1318.3 924.08 284.76 1121.7 1009.3 TRUE FALSE FALSE 1269.482355 1423.44785 1313.645016 1117.65622 1190.334739 1044.86972 950.0071978 371.5820131 998.6523164 1044.3731 1.215544862 1.362968703 1.257831149 1.070169483 1.139760053 1.00047552 0.909643496 0.355794316 0.956221791 1 10.02842149 -4.199923549 1.442805529 1.134194604 2.91E-16 0.800900345 0.116955059 0.495356997 0.821947157 0.018665751 0.839217482 6.31E-05 4.199923549 -1.134194604 down ALDMLQMASSPIASS(ph)SNR ddPTM_HeLa_Curcumin_4h_R1 1 ALDMLQMASSPIASSSNR 18 0 Q96MY7;Q96MY7-2 Q96MY7 FAM161B Protein FAM161B 1 0 ALDMLQMAS(0.001)SPIAS(0.039)S(0.758)S(0.203)NR 67.685 0.005843 0 308.07 307.96 357.31 261.28 299 326.94 259.26 55.273 363.21 281.03 TRUE FALSE FALSE 283.6859344 334.5786902 370.5522229 260.1988926 295.4346203 259.1289586 266.5341378 72.12548325 323.3667717 290.7957716 0.975550411 1.150562432 1.274269639 0.894782242 1.015952256 0.891102911 0.916568134 0.248027964 1.112006443 1 8.183862481 -4.199887266 2.304753208 1.010660707 4.93E-19 0.810180145 0.113568844 0.241607314 1.298271419 0.015619764 0.520186532 6.31E-05 4.199887266 -1.010660707 down GLLSDS(ph)MTDVPVDTGVAAR ddPTM_HeLa_Curcumin_4h_R1 3 GLLSDSMTDVPVDTGVAAR 19 0 O43399;O43399-5;O43399-7;A0A087WYR3;O43399-2;O43399-4;O43399-3;A0A087WZ51 O43399 TPD52L2 Tumor protein D54 1 0 GLLS(0.015)DS(0.981)MT(0.003)DVPVDTGVAAR;GLLS(0.024)DS(0.969)MT(0.007)DVPVDTGVAAR;GLLS(0.002)DS(0.644)MT(0.355)DVPVDTGVAAR ;; 162.15 1.68E-15 121108000 6848.3 5369.8 6385.3 7096 6183.5 6838.8 4524.26 1802.46 5677.14 6270.24 TRUE FALSE FALSE 6306.249829 5833.941585 6621.944835 7066.638632 6109.765801 5420.355791 4651.198559 2352.021756 5054.371946 6488.130373 0.971967187 0.899171448 1.020624503 1.089164093 0.941683574 0.83542646 0.716878098 0.362511482 0.779018246 1 12.66358709 -4.199654619 1.082993509 0.988493656 1.49E-18 0.826320523 0.082698446 0.326301692 0.27698004 0.00772246 0.380204038 6.31E-05 4.199654619 -0.988493656 down SKEGDVEEPTDDS(ph)LPTTGDAGGREPMEEK ddPTM_HeLa_Curcumin_4h_R1 1 SKEGDVEEPTDDSLPTTGDAGGREPMEEK 29 2 Q9UKN8 Q9UKN8 GTF3C4 General transcription factor 3C polypeptide 4 1 0 SKEGDVEEPT(0.042)DDS(0.893)LPT(0.033)T(0.033)GDAGGREPMEEK 78.645 2.92E-06 14692000 2454.4 1884.7 2179.3 2045.8 2060.4 2331 2235.8 1720.3 2593.6 2475.8 TRUE FALSE FALSE 2260.13165 2047.60507 2260.066775 2037.335022 2035.831076 1847.524324 2298.530531 2244.811551 2309.088569 2561.833866 0.882231936 0.799273168 0.882206612 0.795264302 0.794677244 0.721172574 0.897220761 0.876251806 0.901342042 1 11.3229612 -8.289219437 0.58360657 0.998092749 0.816847589 0.390650308 0.057949883 0.363865009 0.271397649 0.02945907 0.014636174 5.14E-09 8.289219437 -0.18124516 SKEGHSLEMENENLVENGADS(ph)DEDDNSFLK ddPTM_HeLa_Curcumin_4h_R1 2 SKEGHSLEMENENLVENGADSDEDDNSFLK 30 1 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 S(0.001)KEGHS(0.001)LEMENENLVENGADS(0.867)DEDDNS(0.132)FLK;SKEGHSLEMENENLVENGADS(0.973)DEDDNS(0.027)FLK ; 66.972 7.06E-05 160777000 4704.8 3877.4 3567 3816.3 6194.3 7829.2 4503.6 3829.6 5128.4 3572.7 TRUE FALSE FALSE 4332.410116 4212.545179 3699.196158 3800.509162 6120.437018 6205.335667 4629.958895 4997.227411 4565.827351 3696.851059 1.171919032 1.139495509 1.00063435 1.028039567 1.655581174 1.6785463 1.252406121 1.351752432 1.235058507 1 11.85208121 -5.772448424 24.99997157 1.077899572 1.481843612 0.654610928 0.137948924 95.89586367 217766.0565 0.020897402 0.038141343 1.69E-06 5.772448424 0.40394404 SKENMAQESSIQEQGVTSNTS(ph)DSESSSK ddPTM_HeLa_Curcumin_4h_R1 2 SKENMAQESSIQEQGVTSNTSDSESSSK 28 1 Q92796-3;Q92796-2 Q92796-3 1 0 S(0.003)KENMAQES(0.008)S(0.008)IQEQGVT(0.01)S(0.02)NT(0.302)S(0.5)DS(0.109)ES(0.025)S(0.01)S(0.004)K;SKENMAQESSIQEQGVTS(0.009)NT(0.253)S(0.431)DS(0.253)ES(0.045)S(0.006)S(0.002)K ; 82.198 2.30E-05 9925400 1698.48 1790.96 2096.56 1603.5 1819.74 1815.74 1653.83 1091.65 1820.13 1565 TRUE FALSE FALSE 1564.043516 1945.762602 2174.260358 1596.865142 1798.040789 1439.135056 1700.232019 1424.48906 1620.466293 1619.383634 0.965826431 1.201545182 1.342646864 0.986094406 1.11032417 0.888693097 1.049925406 0.879648917 1.000668563 1 10.66122909 -3.064817294 12.57998714 1.020949047 0.711871231 0 0.136928034 0 0 0.018453087 0 0.000861356 3.064817294 -0.309077816 SKESVPEFPLS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 6 SKESVPEFPLSPPK 14 1 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 1 0 SKESVPEFPLS(1)PPK;S(0.003)KES(0.002)VPEFPLS(0.995)PPK;SKESVPEFPLS(1)PPK;SKESVPEFPLS(1)PPK;S(0.009)KES(0.009)VPEFPLS(0.982)PPK;SKESVPEFPLS(1)PPK ;;;;; 133.45 0.00049252 6945020600 19738 34029.9 19033 23492.9 19247 22301.6 17820.1 14206.1 21182.8 19080.7 TRUE FALSE FALSE 18175.71647 36971.29292 19738.37972 23395.6926 19017.4921 17675.99677 18320.08405 18537.47449 18859.09984 19743.7529 0.920580629 1.872556504 0.999727854 1.184966846 0.963215666 0.89527036 0.927892693 0.938903287 0.955193267 1 14.26910862 -5.537874633 23.75900519 1.055253448 0.922714757 0.078872907 0.268353641 361.8131025 573243.468 0.040802779 0.081636144 2.90E-06 5.537874633 -0.132538692 SKESVPEFPLS(ph)PPKK ddPTM_HeLa_Curcumin_4h_R1 1 SKESVPEFPLSPPKK 15 2 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 1 0 SKESVPEFPLS(1)PPKK 93.5 0.0044695 14054000 1475.6 1578.8 1455.7 1191.6 1645.8 1842.5 1394 1141.3 1748.6 1591 TRUE FALSE FALSE 1358.804703 1715.264437 1509.649523 1186.669475 1626.17491 1460.344731 1433.111888 1489.277116 1556.782955 1646.287132 0.82537528 1.041898709 0.917002565 0.720815617 0.987783284 0.887053481 0.870511505 0.904627806 0.945632706 1 10.68500027 -9.571190525 1.317096945 1.000677975 0.887076132 0.108378534 0.083358706 0.574229768 1.768201017 0.058666384 0.013400278 2.68E-10 9.571190525 -0.113601843 SKESVPEFPLSPPK ddPTM_HeLa_Curcumin_4h_R1 2 SKESVPEFPLSPPK 14 1 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 0 0 ; ; 108.97 0.00092179 6975900 8046.2 7162.8 7112.3 7559.6 7041.8 8940.2 7480 7624.4 9204.5 7256 FALSE FALSE TRUE 7409.33478 7781.920515 7375.888095 7528.320378 6957.831134 7085.901743 7689.868669 9949.044462 8194.789379 7508.14546 0.986839536 1.036463739 0.982384816 1.002687071 0.92670436 0.943761916 1.024203475 1.325100122 1.091453199 1 12.87424089 -4.266835985 4.033085762 0.988873949 1.353059738 0.833555201 0.043708842 0.043422759 1.486363754 0.004145728 0.045619521 5.41E-05 4.266835985 0.364185789 SKETSSPGTDDVFTPAPS(ph)DSPSSQR ddPTM_HeLa_Curcumin_4h_R1 1 SKETSSPGTDDVFTPAPSDSPSSQR 25 1 P19634 P19634 SLC9A1 Sodium/hydrogen exchanger 1 1 0 SKETSSPGTDDVFTPAPS(0.793)DS(0.177)PS(0.022)S(0.007)QR 148.61 2.01E-08 9836400 1967.8 1701.3 1726.2 2721.7 1623.1 3911.5 1222.7 588.75 3721.3 1893.1 TRUE FALSE FALSE 1812.046554 1848.352791 1790.174491 2710.438327 1603.745593 3100.210808 1257.005671 768.2571647 3313.0827 1958.885084 0.925039742 0.943573876 0.913874175 1.383663773 0.818703254 1.582640469 0.641694442 0.392191033 1.691310392 1 10.93581705 -4.534870771 24.99716188 1.014866092 0.454566613 0.346670438 0.313352622 111.9930682 233447.9627 0.02899023 0.108629358 2.92E-05 4.534870771 -0.560299479 SKFDS(ph)DEEEEDTENVEAASSGK ddPTM_HeLa_Curcumin_4h_R1 1 SKFDSDEEEEDTENVEAASSGK 22 1 Q8TF01;Q8TF01-2 Q8TF01 PNISR Arginine/serine-rich protein PNISR 1 0 S(0.474)KFDS(0.519)DEEEEDT(0.007)ENVEAASSGK 53.39 0.0080073 25637000 4122.7 2774 3559.6 3752.2 3579.5 3986.5 3645.8 2734.7 3289.8 2650.4 TRUE FALSE FALSE 3796.383945 3013.772199 3691.521907 3736.674391 3536.8168 3159.654963 3748.091336 3568.497441 2928.917171 2742.501203 1.384277951 1.09891372 1.346042038 1.362506017 1.289631814 1.152107047 1.366668985 1.301183546 1.067972976 1 11.42127654 -9.430083767 1.020568404 0.990328406 1.293048517 0.551313025 0.09087403 0.31257089 0.551399076 0.072104307 0.015901264 3.71E-10 9.430083767 0.302720111 SYSSSS(ph)SS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 SYSSSSSSPER 11 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 2 0 SYS(0.001)S(0.011)S(0.165)S(0.822)S(0.307)S(0.693)PER 108.35 0.017479 5767200 5994.3 6143.6 5686.8 6108.5 5646.6 6232.4 4239.5 1759.4 6246.6 4731.6 TRUE FALSE FALSE 5519.84483 6674.625409 5897.557811 6083.224646 5579.267983 4939.729986 4358.44896 2295.832961 5561.363608 4896.022748 1.127414049 1.363274999 1.20456095 1.242482921 1.139551074 1.008927091 0.890201942 0.468917952 1.135894152 1 12.25739455 -4.199291381 1.431182324 1.113195267 0.140405383 0.806875775 0.102798577 0.581451423 0.945363936 0.018560366 0.839755358 6.32E-05 4.199291381 -0.972789884 down SKGHYEVT(ph)GSDDETGKLQGSGVSLASK ddPTM_HeLa_Curcumin_4h_R1 1 SKGHYEVTGSDDETGKLQGSGVSLASK 27 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 S(0.003)KGHY(0.045)EVT(0.824)GS(0.127)DDET(0.001)GKLQGSGVSLASK 81.553 6.12E-05 0 467.56 409.88 471.62 282.37 376.16 683.17 491.89 249.2 515.01 377.18 TRUE FALSE FALSE 430.5521326 445.3082008 489.0986521 281.2016278 371.6745377 541.4728411 505.6911095 325.1799328 458.5146915 390.2869769 1.103168074 1.140976325 1.253176972 0.720499644 0.952310888 1.38737102 1.295690452 0.833181613 1.174814223 1 8.608391514 -9.180561113 0.940545777 1.000279941 1.093371926 0 0.202702268 2.083493761 3.335608705 0.129214397 0.037234156 6.60E-10 9.180561113 0.093091985 SKGHYEVTGS(ph)DDETGK ddPTM_HeLa_Curcumin_4h_R1 2 SKGHYEVTGSDDETGK 16 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 SKGHYEVT(0.032)GS(0.964)DDET(0.003)GK;SKGHYEVT(0.028)GS(0.964)DDET(0.007)GK ; 66.261 0.011428 28452600 13040.1 10872.4 10170.7 9219.7 19505.3 27665.5 13496.7 6253.2 15676.4 10518.2 TRUE FALSE FALSE 12007.96233 11812.16181 10547.63509 9181.551324 19272.71204 21927.36345 13875.38108 8159.771894 13956.73814 10883.70667 1.10329713 1.085306888 0.969121588 0.84360518 1.770785692 2.01469629 1.274876428 0.749723614 1.282351552 1 13.40988236 -5.769429274 24.99988904 1.033497452 1.479987072 0.269573944 0.325060507 164.6868197 515296.3414 0.047304257 0.086859343 1.70E-06 5.769429274 0.446489619 SKGHYEVTGS(ph)DDETGKLQGSGVSLASK ddPTM_HeLa_Curcumin_4h_R1 1 SKGHYEVTGSDDETGKLQGSGVSLASK 27 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 SKGHYEVT(0.005)GS(0.756)DDET(0.235)GKLQGS(0.003)GVS(0.001)LASK 72.082 9.92E-05 89228000 3841.6 3001.6 2646.1 3051.3 4560.8 8518.8 3563.5 1811.6 5533.3 3268.6 TRUE FALSE FALSE 3537.533306 3261.044929 2744.166794 3038.674529 4506.415439 6751.904853 3663.482219 2363.9485 4926.310834 3382.183607 1.045931776 0.964183293 0.811359498 0.89843571 1.332398226 1.996315292 1.08317071 0.698941505 1.456547428 1 11.72373927 -5.753009582 24.87096521 0.992171879 1.315140309 0.103687994 0.340391998 222.0332989 655073.0712 0.044819787 0.08847211 1.77E-06 5.753009582 0.32296843 SKGQESFK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 SKGQESFKK 9 2 P06748;P06748-3 P06748 NPM1 Nucleophosmin 0 1 ; SKGQESFK(1)K;SKGQESFK(1)K 104.07 0.0012468 70338000 11629.3 10191.4 11798 9707.9 11790.5 14737.6 13305.2 14262.6 10744.1 10932.2 FALSE TRUE FALSE 10708.82863 11072.2992 12235.24426 9667.731282 11649.90599 11680.85563 13678.5081 18611.20108 9565.49911 11312.09314 0.946670833 0.978801984 1.081607454 0.854636818 1.029862984 1.032598962 1.209193377 1.645248219 0.845599395 1 13.46557828 -4.125338287 1.370633625 0.976371398 2.098666641 0.901586936 0.068588179 0.281831835 0.365446964 0.007546508 0.475209838 7.49E-05 4.125338287 1.122295243 SKHEEEEWT(ph)DDDLVESL ddPTM_HeLa_Curcumin_4h_R1 2 SKHEEEEWTDDDLVESL 17 1 D6RHI7;P51946 D6RHI7 CCNH Cyclin-H 1 0 SKHEEEEWT(0.999)DDDLVES(0.001)L;SKHEEEEWT(1)DDDLVESL ; 100.11 0.0017686 71402000 10834.1 9108.3 8596.9 7492.3 14341 22770.9 12235 9567.2 14722.9 9855.4 TRUE FALSE FALSE 9976.569553 9895.580866 8915.508677 7461.298848 14169.99294 18047.95866 12578.28117 12484.19524 13107.8347 10197.87442 0.978298922 0.9703572 0.874251664 0.731652356 1.389504554 1.769776516 1.233421854 1.22419582 1.285349689 1 13.31598086 -5.694574935 8.910268026 0.962290663 1.420189117 0.550065238 0.190596851 0.144553909 17.72257369 0.023407166 0.04683635 2.02E-06 5.694574935 0.457898454 SKLPDGPTGS(ph)SEEEEEFLEIPPFNK ddPTM_HeLa_Curcumin_4h_R1 2 SKLPDGPTGSSEEEEEFLEIPPFNK 25 1 A6NNK5;Q12888;Q12888-3;Q12888-2 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 S(0.013)KLPDGPT(0.053)GS(0.467)S(0.467)EEEEEFLEIPPFNK;SKLPDGPT(0.109)GS(0.445)S(0.445)EEEEEFLEIPPFNK ; 65.881 0.00052468 39710000 3518.5 2806.2 2662.4 2784.7 3088.1 3762.5 3025.5 2618.2 3289 3267.4 TRUE FALSE FALSE 3240.007012 3048.755424 2761.070886 2773.177649 3051.276424 2982.115088 3110.387387 3416.477127 2928.204929 3380.941907 0.958314902 0.901747356 0.816657299 0.820238184 0.902493006 0.882036773 0.919976584 1.01051045 0.866091465 1 11.72320951 -7.395469898 2.343816628 0.983573134 0.88809612 0 0.063413161 0.226450521 2.361356362 0.010061135 0.011363595 4.02E-08 7.395469898 -0.095477013 SKLTFSCLGGSDNFK ddPTM_HeLa_Curcumin_4h_R1 1 SKLTFSCLGGSDNFK 15 1 A0A087WYT3;Q15185-4;Q15185;Q15185-2;Q15185-3 A0A087WYT3 PTGES3 Prostaglandin E synthase 3 0 0 84.41 0.011709 1552600 882.67 656.21 980.16 621.56 569.48 1344.8 764.93 845.57 903.61 651.76 FALSE FALSE TRUE 812.8057381 712.9298684 1016.485592 618.9881494 562.6893229 1065.873321 786.3918771 1103.3804 804.4862437 674.4086115 1.205212573 1.057118572 1.507225107 0.917823614 0.834344807 1.580456274 1.166046613 1.636071043 1.192876588 1 9.397479148 -1.000004355 0.644068595 1.104063512 44.22871546 0.297486851 0.222281856 174.1841901 1.065039298 0.036470555 10719.14792 0.099998997 1.000004355 43.12465195 SKPIPIMPAS(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 2 SKPIPIMPASPQK 13 1 O00429-7;O00429-4;O00429-5;O00429-3;O00429-9;O00429-2;O00429;O00429-8;O00429-6 O00429-7 DNM1L Dynamin-1-like protein 1 0 SKPIPIMPAS(1)PQK;SKPIPIMPAS(1)PQK ; 145.79 0.0070526 136670000 16435.8 13517.4 16838.1 15325.2 17211.7 16973.8 14211 12657.1 14011.2 12804 TRUE FALSE FALSE 15134.88909 14685.78382 17462.1348 15261.78838 17006.46172 13453.24255 14609.72241 16516.19152 12474.20641 13248.93805 1.142347336 1.108449883 1.3180026 1.151925409 1.283609423 1.015420443 1.102708939 1.246604933 0.941525001 1 13.69358911 -8.711787011 0.661676674 0.999530567 1.173426651 0.441152135 0.08842737 0.624241345 0.528699402 0.055626308 0.019872878 1.94E-09 8.711787011 0.173896085 SKPIPIMPAS(ph)PQKGHAVNLLDVPVPVAR ddPTM_HeLa_Curcumin_4h_R1 3 SKPIPIMPASPQKGHAVNLLDVPVPVAR 28 2 O00429-7;O00429-4;O00429-5;O00429-3;O00429-9;O00429-2;O00429;O00429-8;O00429-6 O00429-7 DNM1L Dynamin-1-like protein 1 0 SKPIPIMPAS(1)PQKGHAVNLLDVPVPVAR;S(0.452)KPIPIMPAS(0.548)PQKGHAVNLLDVPVPVAR;S(0.002)KPIPIMPAS(0.998)PQKGHAVNLLDVPVPVAR ;; 73.072 6.64E-05 288333000 8772.3 6436.2 7281.1 7076.6 7125.8 9804.6 7434.3 6992.1 8998 7390.5 TRUE FALSE FALSE 8077.963199 6992.516449 7550.943971 7047.318904 7040.829489 7771.015439 7642.88645 9123.959102 8010.941912 7647.319325 1.05631305 0.914374848 0.987397498 0.921541079 0.920692492 1.016175095 0.999420336 1.19309247 1.047549026 1 12.9007384 -4.261158951 23.43066489 1.000876996 1.193092576 0.586604719 0.050868869 6.092175359 508339.565 0.007900718 0.061683911 5.48E-05 4.261158951 0.19221558 SKPLAAS(ph)PKPAGLK ddPTM_HeLa_Curcumin_4h_R1 1 SKPLAASPKPAGLK 14 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 SKPLAAS(1)PKPAGLK 50.252 0.019264 835470000 6668.6 5448.1 6770.8 6095.7 6951.8 7399.2 6131.3 2633.9 6481.9 5062.7 TRUE FALSE FALSE 6140.773273 5919.009488 7021.731804 6070.477609 6868.904325 5864.522514 6303.327776 3436.963985 5770.851787 5238.628448 1.172210118 1.129877705 1.340375992 1.158791403 1.311202807 1.119476705 1.203240092 0.656080884 1.101595932 1 12.35497343 -4.25623912 24.99662766 1.132473349 0.656080686 0.690118285 0.100561214 306.3098179 1472324.289 0.01665419 0.188780887 5.54E-05 4.25623912 -0.476392663 SKPLAASPKPAGLKESS(ph)DK ddPTM_HeLa_Curcumin_4h_R1 1 SKPLAASPKPAGLKESSDK 19 3 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 SKPLAAS(0.001)PKPAGLKES(0.43)S(0.569)DK 59.281 0.011471 118220000 2149.4 1687 1707.7 2149.2 1196.9 2155 1825.3 860.97 2235.1 2220.6 TRUE FALSE FALSE 1979.272722 1832.816763 1770.988864 2140.30718 1182.627749 1708.028708 1876.513005 1123.47579 1989.915122 2297.765685 0.861390147 0.797651725 0.770743891 0.931473211 0.514685965 0.743343292 0.816668565 0.488942714 0.866021777 1 11.16601597 -3.430723058 0.106341406 1.170540964 2.50E-09 0.43239891 0.117575532 31.90819348 0.432138477 0.899429876 5.602333811 0.000370917 3.430723058 -1.170540962 SKPNLPSESRS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SKPNLPSESRSR 12 2 Q08170 Q08170 SRSF4 Serine/arginine-rich splicing factor 4 1 0 SKPNLPS(0.008)ES(0.229)RS(0.763)R 75.911 0.0085538 12304000 3404.6 2504.3 2337.5 3135 2160.8 3671 2382 2386.3 3541 3012.8 TRUE FALSE FALSE 3135.122317 2720.760533 2424.129806 3122.028201 2135.033871 2909.593219 2448.832509 3113.871885 3152.561159 3117.494576 1.005654458 0.87273946 0.777589102 1.001454253 0.684855681 0.933311398 0.785512998 0.998837948 1.011248322 1 11.60617133 -7.240002164 5.63920023 1.002841291 0.858893489 0.320229188 0.09376125 0.135347204 14.66512945 0.01386394 0.016687041 5.75E-08 7.240002164 -0.143947802 SKPPPTYES(ph)EEEDK ddPTM_HeLa_Curcumin_4h_R1 1 SKPPPTYESEEEDK 14 1 O60885;O60885-2;O60885-3 O60885 BRD4 Bromodomain-containing protein 4 1 0 S(0.093)KPPPT(0.025)YES(0.882)EEEDK 203.92 4.79E-08 14330000 1698.2 1835.4 1800 1903.3 2152.9 2165.9 1885.5 1685 2091 1496.6 TRUE FALSE FALSE 1563.785678 1994.043798 1866.709583 1895.424649 2127.228074 1716.667925 1938.402055 2198.748743 1861.622531 1548.606739 1.009801675 1.287637299 1.205412282 1.223954799 1.373639944 1.108524122 1.251707104 1.419823825 1.202127361 1 10.59675511 -7.265963468 24.29557358 1.00462856 1.260589864 0.391150116 0.102718494 101.7689995 546525.9031 0.013100987 0.01525574 5.42E-08 7.265963468 0.255961305 T(ph)ASPLPLRPDAPVEKS(ph)PEETATQVPSLESLTLK ddPTM_HeLa_Curcumin_4h_R1 1 TASPLPLRPDAPVEKSPEETATQVPSLESLTLK 33 2 Q9HCK8-2;Q9HCK8;H0YJG4 Q9HCK8-2 CHD8 Chromodomain-helicase-DNA-binding protein 8 2 0 T(0.487)AS(0.443)PLPLRPDAPVEKS(0.548)PEET(0.217)AT(0.302)QVPS(0.002)LESLTLK 48.226 0.004871 73062000 2097.7 1329.3 1658.7 1767.7 1645 1259.1 1322.6 509.93 2251.3 1637.6 TRUE FALSE FALSE 1931.664832 1444.198769 1720.172881 1760.385726 1625.384449 997.948467 1359.708596 665.4053096 2004.338022 1694.506478 1.139957183 0.852282825 1.015146831 1.038878133 0.959208165 0.588931633 0.802421598 0.392683839 1.182844709 1 10.72664944 -4.199086306 0.562726934 1.058353183 4.65E-13 0.748726505 0.117503878 1.383801976 0.280922824 0.021410523 0.968399083 6.32E-05 4.199086306 -1.058353183 down SKPVLEPLT(ph)PPLGSPRPR ddPTM_HeLa_Curcumin_4h_R1 1 SKPVLEPLTPPLGSPRPR 18 2 Q9H7P9-3;Q9H7P9;H7BXC7;E7ESZ3;Q9H7P9-2 Q9H7P9-3 PLEKHG2 Pleckstrin homology domain-containing family G member 2 1 0 SKPVLEPLT(1)PPLGSPRPR 142.89 0.00052317 35421000 1827 991.5 1159.3 1133.7 1234.3 1458 1114.1 549.02 1778.8 1493.1 TRUE FALSE FALSE 1682.391022 1077.200842 1202.264678 1129.00905 1219.581779 1155.594365 1145.358648 716.4136706 1583.67009 1544.985114 1.08893672 0.697224091 0.778172338 0.730757235 0.789380925 0.747964724 0.741339601 0.463702636 1.025039061 1 10.59337722 -7.258492232 24.97188864 1.041997898 0.716663049 0.742722156 0.089151663 90.80287108 769395.6964 0.014919116 0.017852169 5.51E-08 7.258492232 -0.32533485 SKQSETVDQNS(ph)DS(ph)DEMLAILK ddPTM_HeLa_Curcumin_4h_R1 1 SKQSETVDQNSDSDEMLAILK 21 1 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6;A0A096LNW1 P46100-5 ATRX Transcriptional regulator ATRX 2 0 SKQSETVDQNS(1)DS(1)DEMLAILK 61.942 0.016834 15397000 1633.2 1403.2 1418.8 1746 1241.9 1965.9 1301.9 1118 2692.2 2023.9 TRUE FALSE FALSE 1503.930497 1524.486355 1471.381976 1738.775515 1227.091154 1558.15018 1338.42781 1458.873053 2396.872396 2094.230374 0.7181304 0.727945872 0.702588404 0.830269456 0.585938953 0.744020428 0.639102472 0.696615363 1.144512287 1 11.03220444 -9.657057325 0.379699204 1.150774789 0.682758545 0.78913386 0.07433874 1.060985542 0.159739885 0.20992414 0.019858654 2.20E-10 9.657057325 -0.468016244 SKQSETVDQNS(ph)DSDEMLAILK ddPTM_HeLa_Curcumin_4h_R1 3 SKQSETVDQNSDSDEMLAILK 21 1 P46100-5;P46100-3;P46100-4;P46100;P46100-2;A0A096LNL9;P46100-6;A0A096LNW1 P46100-5 ATRX Transcriptional regulator ATRX 1 0 SKQSETVDQNS(0.885)DS(0.115)DEMLAILK;SKQSETVDQNS(0.868)DS(0.132)DEMLAILK;SKQSETVDQNS(0.75)DS(0.25)DEMLAILK ;; 99.313 0.00019908 39940700 8398.9 6022.8 6040.2 7746.9 5291.1 8301.1 6016.9 3959.5 9293.9 7982.1 TRUE FALSE FALSE 7734.118203 6543.383995 6264.055126 7714.84538 5228.007088 6579.358287 6185.71802 5166.733323 8274.382422 8259.477381 0.936393169 0.792227364 0.75840817 0.93405975 0.632970689 0.796582881 0.748923659 0.625552088 1.001804599 1 13.01183478 -6.617559904 0.350871674 1.01567557 0.652288562 0.667709419 0.076233272 0.630192391 0.180163024 0.041715129 0.088151834 2.41E-07 6.617559904 -0.363387008 SKS(ph)AT(ph)TTPSGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 SKSATTTPSGSPR 13 1 Q2M2I8-2;Q2M2I8;A0A096LP60;A0A096LNZ0;A0A096LP25 Q2M2I8-2;A0A096LNZ0 AAK1 AP2-associated protein kinase 1 3 0 S(0.087)KS(0.834)AT(0.416)T(0.423)T(0.242)PS(0.063)GS(0.936)PR;S(0.396)KS(0.734)AT(0.49)T(0.205)T(0.173)PS(0.365)GS(0.636)PR ; 92.952 0.0045798 21930000 14845.3 12703.7 13971.3 14788.2 13782.1 10336.4 6055.2 5666.8 13079 12770.1 TRUE FALSE FALSE 13670.27884 13801.75122 14489.08867 14727.01035 13617.75746 8192.514125 6225.092615 7394.581233 11644.26642 13213.86002 1.034540915 1.044490497 1.096506898 1.114512362 1.030566196 0.619994015 0.471103266 0.559607959 0.881216117 1 13.68976435 -5.199215187 3.697333554 1.034309825 0.522067651 0.923445703 0.063520491 0.031907691 0.871649759 0.006804147 0.018383565 6.32E-06 5.199215187 -0.512242174 SKS(ph)DGEAKPEPSPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SKSDGEAKPEPSPSPR 16 2 P26358;K7EJL0;K7ERQ1;K7ENQ6 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 2 0 S(0.207)KS(0.793)DGEAKPEPS(0.057)PS(0.943)PR 73.404 0.015109 6031600 2677.7 2373.9 2562.4 3132.6 2643.7 2911.2 2160.1 2944.6 2756.6 2474.5 TRUE FALSE FALSE 2465.75722 2579.089338 2657.364798 3119.638131 2612.175604 2307.384304 2220.706592 3842.394985 2454.207877 2560.488691 0.963002582 1.007264491 1.037835007 1.218376063 1.020186347 0.901149969 0.86729795 1.500649075 0.958491981 1 11.32220347 -4.25245829 24.85946569 0.994586464 1.500649358 0.740337498 0.089459899 434.9146876 1203806.94 0.012672478 0.20592171 5.59E-05 4.25245829 0.506062894 SKS(ph)PASTSSVNGTPGSQLSTPR ddPTM_HeLa_Curcumin_4h_R1 3 SKSPASTSSVNGTPGSQLSTPR 22 1 Q5VZY9;O15075-2;O15075 Q5VZY9 DCLK1 Serine/threonine-protein kinase DCLK1 1 0 S(0.157)KS(0.842)PAS(0.001)TSSVNGTPGSQLSTPR;S(0.07)KS(0.885)PAS(0.037)T(0.007)S(0.001)S(0.001)VNGTPGSQLSTPR;S(0.141)KS(0.809)PAS(0.008)T(0.041)S(0.001)SVNGTPGSQLSTPR ;; 124.73 4.45E-06 54464400 3631.31 3127.19 3316.93 3519.8 3353.05 4390 3778.2 3794.98 4150 3522.61 TRUE FALSE FALSE 3343.887982 3397.490369 3439.858344 3505.236 3313.067069 3479.464515 3884.206123 4952.051932 3694.755383 3645.020435 0.91738525 0.932090898 0.943714419 0.961650576 0.908929628 0.954580249 1.065619848 1.358580019 1.013644628 1 11.83171119 -4.273424343 2.163524803 0.952729998 1.461301029 0.937686562 0.031495352 0.118248742 0.627873391 0.004982721 0.114621853 5.33E-05 4.273424343 0.50857103 SKS(ph)PASVNGTPSSQLSTPK ddPTM_HeLa_Curcumin_4h_R1 1 SKSPASVNGTPSSQLSTPK 19 1 G5E9L9;Q8N568-2;Q8N568 G5E9L9 DCLK2 Serine/threonine-protein kinase DCLK2 1 0 S(0.138)KS(0.831)PAS(0.03)VNGT(0.001)PSSQLSTPK 91.175 0.00078419 26046000 3497.9 2847.7 3015.7 3210.8 2852.7 3390.9 3271.6 3305.1 3315.6 3059.9 TRUE FALSE FALSE 3221.037524 3093.842499 3127.464495 3197.51456 2818.683416 2687.589117 3363.392291 4312.809775 2951.886975 3166.231297 1.017309609 0.977137236 0.987756169 1.009880284 0.890232946 0.848829054 1.062269928 1.362127201 0.932303012 1 11.62855093 -4.297896636 3.704834701 0.987067195 1.389225697 0.80527393 0.058341556 0.080445739 2.014777734 0.008373097 0.082792234 5.04E-05 4.297896636 0.402158502 SKS(ph)PPKVPIVIQDDSLPAGPPPQIR ddPTM_HeLa_Curcumin_4h_R1 1 SKSPPKVPIVIQDDSLPAGPPPQIR 25 2 Q7Z422-4;Q7Z422-5;Q7Z422;Q7Z422-2;Q7Z422-3 Q7Z422-4 SZRD1 SUZ domain-containing protein 1 1 0 S(0.154)KS(0.846)PPKVPIVIQDDSLPAGPPPQIR 123.84 2.83E-08 206620000 2917.4 2330.5 2530.2 3436.7 2472.8 3093.7 2786 2868.8 2917.6 2255.6 TRUE FALSE FALSE 2686.484712 2531.938035 2623.971438 3422.479846 2443.313475 2452.031747 2864.167662 3743.483914 2597.546579 2333.981932 1.151030638 1.084814754 1.12424668 1.466369469 1.046843354 1.050578718 1.227159312 1.60390441 1.112924888 1 11.18857768 -4.297489306 2.748894035 1.103079322 1.677381879 0.561208896 0.123545507 0.222568852 2.373258958 0.018464121 0.276520242 5.04E-05 4.297489306 0.574302557 SKS(ph)QSSGSSATHPISVPGAR ddPTM_HeLa_Curcumin_4h_R1 1 SKSQSSGSSATHPISVPGAR 20 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 S(0.022)KS(0.786)QS(0.083)S(0.022)GS(0.027)S(0.033)AT(0.027)HPISVPGAR 59.359 0.0078314 16724000 1118.1 907.57 937.11 1151.7 1894.4 3666.8 1394.9 531.68 1978.2 967.65 TRUE FALSE FALSE 1029.601205 986.0163067 971.840121 1146.934571 1871.810517 2906.264347 1434.03714 693.7867844 1761.196409 1001.275765 1.028289349 0.984759984 0.970601861 1.145473215 1.869425569 2.902561359 1.432209976 0.692902803 1.758952398 1 9.967623652 -5.82990293 5.033175887 1.011251674 1.787243226 0.178192348 0.56051988 0.177964785 8.525690997 0.075290685 0.140253469 1.48E-06 5.82990293 0.775991553 SKSDGEAKPEPS(ph)PSPR ddPTM_HeLa_Curcumin_4h_R1 1 SKSDGEAKPEPSPSPR 16 2 P26358;K7EJL0;K7ERQ1;K7ENQ6 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 0 SKSDGEAKPEPS(0.612)PS(0.388)PR 72.968 0.015238 27520000 1857 1379.1 1074.4 1835.2 1561.2 2114.1 1359.4 827.61 1848 1684.5 TRUE FALSE FALSE 1710.016491 1498.303259 1114.218209 1827.606429 1542.58371 1675.611829 1397.541105 1079.944479 1645.279023 1743.03625 0.981056183 0.859593861 0.639239838 1.048518887 0.884998066 0.961317832 0.801785451 0.619576603 0.943915552 1 10.76738686 -2.074522185 0.225769043 1.007487649 1.62E-20 0.267503781 0.119726664 27.24625219 0.503412564 0.089093304 9.197328151 0.008423214 2.074522185 -1.007487649 SKSDGEAKPEPSPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SKSDGEAKPEPSPSPR 16 2 P26358;K7EJL0;K7ERQ1;K7ENQ6 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 0 SKSDGEAKPEPS(0.044)PS(0.956)PR 70.121 0.018036 4536800 1218.6 922.5 1063.2 1178.2 1116.8 1445.8 1236.5 474.85 1219.3 1075 TRUE FALSE FALSE 1122.146524 1002.236789 1102.603127 1173.324921 1103.482889 1145.924782 1271.192862 619.6295791 1085.545841 1112.35617 1.008801456 0.901003488 0.991232086 1.054810458 0.992022986 1.030177935 1.142793016 0.557042426 0.975897711 1 10.11940309 -4.250691105 24.98477356 1.007729884 0.557042167 0.845085704 0.058263332 415.1267553 964959.7403 0.007569391 0.148542523 5.61E-05 4.250691105 -0.450687717 SKSEVIEDS(ph)DVETVSEKK ddPTM_HeLa_Curcumin_4h_R1 1 SKSEVIEDSDVETVSEKK 18 2 Q56NI9;E5RFE4 Q56NI9 ESCO2 N-acetyltransferase ESCO2 1 0 S(0.017)KS(0.017)EVIEDS(0.959)DVET(0.004)VS(0.002)EKK 54.004 0.011481 5460400 1480.8 1541.2 1439.3 1744 1648.3 1971.5 1444 1402.1 1757.5 1807.9 TRUE FALSE FALSE 1363.593117 1674.414461 1492.641724 1736.78379 1628.645099 1562.588677 1484.514754 1829.593836 1564.706647 1870.72439 0.728911819 0.895062078 0.797895046 0.928401746 0.870595961 0.83528535 0.793550756 0.978013568 0.836417516 1 10.86938131 -9.62121722 1.448610076 0.999588366 0.835352572 0 0.085178568 0.328923047 1.244557845 0.051615587 0.011945337 2.39E-10 9.62121722 -0.164235794 SKSPLPPEEEAKDEEEDQT(ph)LVNLDTYTSDLHFQVSK ddPTM_HeLa_Curcumin_4h_R1 2 SKSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK 36 2 Q1KMD3;H3BQZ7 Q1KMD3 HNRNPUL2;HNRNPUL2-BSCL2 Heterogeneous nuclear ribonucleoprotein U-like protein 2 1 0 S(0.026)KS(0.134)PLPPEEEAKDEEEDQT(0.802)LVNLDT(0.016)Y(0.012)T(0.005)S(0.006)DLHFQVSK;S(0.136)KS(0.151)PLPPEEEAKDEEEDQT(0.705)LVNLDT(0.005)Y(0.002)T(0.001)SDLHFQVSK ; 54.926 0.00032546 1104430000 3808.8 2937.8 2779 2702.3 3371.4 4945.8 3678.6 3310.3 4326 3022.5 TRUE FALSE FALSE 3507.329461 3191.730341 2881.992185 2691.118599 3331.198257 3919.985329 3781.811616 4319.595231 3851.448623 3127.53165 1.12143692 1.020526952 0.921490973 0.860460868 1.065120558 1.253379907 1.20920011 1.381151564 1.231465914 1 11.61080877 -5.260165151 3.715659771 1.029591217 1.280380979 0.556218103 0.102901854 0.123629396 3.808084166 0.013613593 0.034971793 5.49E-06 5.260165151 0.250789762 SKST(ph)AALSGEAASCSPIIMPYK ddPTM_HeLa_Curcumin_4h_R1 1 SKSTAALSGEAASCSPIIMPYK 22 1 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;Q14244-2;Q14244-4 Q14244-3 MAP7 Ensconsin 1 0 S(0.277)KS(0.277)T(0.435)AALS(0.012)GEAASCSPIIMPYK 115.83 6.81E-06 25055000 3537.7 2231.9 3390 3369.7 2565.7 3965.8 2838.7 2984.8 2494.4 3348.5 TRUE FALSE FALSE 3257.687312 2424.815491 3515.636382 3355.757074 2535.105703 3143.248376 2918.346282 3894.85178 2220.770561 3464.860126 0.940207452 0.699830701 1.014654634 0.968511557 0.731661773 0.907179009 0.84226958 1.124100725 0.640940898 1 11.7585814 -7.803352333 2.517645276 0.979503604 0.894209825 0 0.160098663 0.451952718 5.904885131 0.022439148 0.021902794 1.57E-08 7.803352333 -0.085293779 SKT(ph)FDWAEFRPIQQALAQER ddPTM_HeLa_Curcumin_4h_R1 1 SKTFDWAEFRPIQQALAQER 20 2 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 S(0.061)KT(0.939)FDWAEFRPIQQALAQER 76.118 0.008267 176810000 980.72 939.33 934.75 893.07 1153 1563.3 1190.5 361.73 1189.8 1079.2 TRUE FALSE FALSE 903.0949771 1020.5215 969.3926573 889.374713 1139.251228 1239.053958 1223.902226 472.0198118 1059.281917 1116.70212 0.808716095 0.913870836 0.868085267 0.796429681 1.02019259 1.109565332 1.095997047 0.422690889 0.948580555 1 10.12502868 -9.623008027 1.455769439 0.99963623 0.884132692 0.037532496 0.185418768 1.126829336 4.3105943 0.124686561 0.028913598 2.38E-10 9.623008027 -0.115503538 SALSS(ph)SLRDLSEAGK ddPTM_HeLa_Curcumin_4h_R1 1 SALSSSLRDLSEAGK 15 1 A0A2R8Y7T6;A0A3B3IRZ4;Q6DN90-2;Q6DN90;Q6DN90-3 A0A2R8Y7T6 IQSEC1 IQ motif and SEC7 domain-containing protein 1 1 0 S(0.014)ALS(0.163)S(0.481)S(0.342)LRDLSEAGK 65.808 0.015676 17301000 3160.1 2654.8 3117.5 2923 3339.5 3464.5 2452.4 766.07 3428 3325.3 TRUE FALSE FALSE 2909.97475 2884.269082 3233.037292 2910.9054 3299.678644 2745.923647 2521.207744 999.6412164 3051.956976 3440.853927 0.845712957 0.838242234 0.93960318 0.845983428 0.958970858 0.798035518 0.732727339 0.290521259 0.886976617 1 11.74855093 -4.197575583 1.435013191 0.914158223 2.70E-18 0.908559481 0.057392226 0.344255211 0.561664229 0.010297457 0.468744863 6.34E-05 4.197575583 -0.914158223 down SKTDNSSLS(ph)SPLNPK ddPTM_HeLa_Curcumin_4h_R1 1 SKTDNSSLSSPLNPK 15 1 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 0 SKTDNSS(0.001)LS(0.5)S(0.5)PLNPK 84.297 0.0053886 34292000 2563.3 1570.3 2261 2954.9 2456.2 4515.9 4076.9 1347.6 3235.9 2509.8 TRUE FALSE FALSE 2360.4121 1706.029735 2344.794649 2942.673407 2426.911419 3579.251435 4191.286842 1758.477036 2880.929866 2597.015363 0.908894161 0.656919385 0.902880546 1.13309819 0.934500217 1.378217274 1.61388604 0.677114607 1.109323382 1 11.34263883 -5.274477489 23.66636287 0.941061292 1.262153972 0.194282295 0.251275439 351.9802706 638904.0229 0.032750124 0.073720783 5.32E-06 5.274477489 0.32109268 SKTDNSSLSS(ph)PLNPK ddPTM_HeLa_Curcumin_4h_R1 1 SKTDNSSLSSPLNPK 15 1 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 0 SKTDNSSLS(0.116)S(0.884)PLNPK 89.669 0.0034756 30658000 5866 3920.4 4641.1 5429.4 5216.5 9643.6 7853.3 2268.5 6620.3 4458.6 TRUE FALSE FALSE 5401.69991 4259.261907 4813.103249 5406.934581 5154.296645 7643.408654 8073.642462 2960.155207 5894.069653 4613.536018 1.170837269 0.923209853 1.043256892 1.171971902 1.117211749 1.656735446 1.749990123 0.641623951 1.277560125 1 12.1716572 -5.44384682 10.14406491 1.074891417 1.389802222 0.125817695 0.291562432 0.640873636 79.61989664 0.037796411 0.084547986 3.60E-06 5.44384682 0.314910806 SKTPSS(ph)PCPASK ddPTM_HeLa_Curcumin_4h_R1 2 SKTPSSPCPASK 12 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 SKTPS(0.173)S(0.826)PCPASK;SKT(0.001)PS(0.196)S(0.797)PCPAS(0.006)K ; 105.17 0.0030668 158831000 9557 7712.8 8792.7 8826.1 8806.4 11271.3 9531.7 2772.2 10424.2 8594.3 TRUE FALSE FALSE 8800.553365 8379.460064 9118.565197 8789.579937 8701.389432 8933.505326 9799.133849 3617.431018 9280.69134 8892.951285 0.989609982 0.942258627 1.02536997 0.988376036 0.978459136 1.004560245 1.101898969 0.406775085 1.04360083 1 13.11844657 -4.255263412 24.99992622 0.997912879 0.406774825 0.949296183 0.041639752 92.93921492 376201.6783 0.004979187 0.061708447 5.56E-05 4.255263412 -0.591138054 SKTS(ph)PVVSGSSSK ddPTM_HeLa_Curcumin_4h_R1 1 SKTSPVVSGSSSK 13 1 H0Y2V6;Q5SW79;Q5SW79-3;Q5SW79-2 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 0 S(0.001)KT(0.223)S(0.776)PVVSGSSSK 77.191 0.011093 97048000 8681.1 7405.6 7640.7 7217.1 6743.2 9269 6530.5 3523.6 8092.9 6474.7 TRUE FALSE FALSE 7993.981775 8045.707065 7923.871063 7187.237552 6662.791744 7346.504917 6713.728254 4597.929419 7205.129117 6699.695343 1.193185864 1.200906407 1.182721103 1.072770803 0.99449175 1.096543132 1.00209456 0.686289329 1.075441307 1 12.70987978 -3.831308609 1.282935373 1.102594578 3.47E-13 0.765066868 0.069293557 1.721365771 1.141667321 0.013392612 3.260971753 0.000147466 3.831308609 -1.102594578 SKVDEAVAVLQAHQAK ddPTM_HeLa_Curcumin_4h_R1 1 SKVDEAVAVLQAHQAK 16 1 P11940;P11940-2;E7EQV3;A0A087WTT1;E7ERJ7;Q9H361;H0YB75;H0YC10;H0YAS6;H0YAS7 P11940 PABPC1;PABPC3 Polyadenylate-binding protein 1;Polyadenylate-binding protein;Polyadenylate-binding protein 3 0 0 104.95 0.000612 2494700 3595.7 2933.1 3717.8 3259.3 3412.8 4431.6 3132.6 3197 3194.4 3600.4 FALSE FALSE TRUE 3311.096551 3186.624094 3855.584939 3245.81388 3372.104589 3512.436206 3220.492325 4171.750583 2843.982312 3725.513632 0.888762431 0.855351613 1.034913657 0.871239298 0.905138169 0.942805893 0.864442502 1.119778639 0.763379924 1 11.86322363 -2.937017832 9.962528849 0.941447254 0.940166597 0 0.099016001 0 0 0.010325513 0 0.001156065 2.937017832 -0.001280657 MDS(ph)FDEDLARPSGLLAQER ddPTM_HeLa_Curcumin_4h_R1 1 MDSFDEDLARPSGLLAQER 19 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 MDS(1)FDEDLARPSGLLAQER 108.69 0.0002373 10728000 1364 1003.8 875.19 1136.8 1286.9 2295.4 2660.4 5211.2 1212.5 1299.5 TRUE FALSE FALSE 1256.037961 1090.563999 907.6253113 1132.096223 1271.554558 1819.308166 2735.043664 6800.070891 1079.491784 1344.657528 0.934095065 0.811034763 0.674986227 0.841921604 0.945634506 1.352989982 2.034007624 5.057102457 0.802800535 1 10.39302306 -3.995925558 1.37833673 0.92317315 9.286033039 0.98980749 0.127231262 0.16783371 0.174263819 0.020095674 2.314867599 0.000100943 3.995925558 8.362859889 up SLAAEEEAAR ddPTM_HeLa_Curcumin_4h_R1 2 SLAAEEEAAR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 136.99 0.00050077 9352000 3820.5 2682.6 2882 3034.8 2922.4 3887.1 2847.9 2905.9 3797.3 3350.6 FALSE FALSE TRUE 3518.103394 2914.471991 2988.809455 3022.242802 2887.552289 3080.871643 2927.804409 3791.895533 3380.74569 3467.033101 1.014730258 0.840624218 0.862065452 0.871708667 0.832859741 0.888619045 0.844469702 1.093700413 0.975112032 1 11.7594859 -7.272190335 24.72081117 1.006955959 0.884687089 0.308134182 0.071937557 432.3944088 994248.5765 0.011343951 0.013044716 5.34E-08 7.272190335 -0.12226887 SLAALDALNT(ph)DDENDEEEYEAWK ddPTM_HeLa_Curcumin_4h_R1 3 SLAALDALNTDDENDEEEYEAWK 23 0 P55081 P55081 MFAP1 Microfibrillar-associated protein 1 1 0 SLAALDALNT(0.984)DDENDEEEY(0.016)EAWK;SLAALDALNT(1)DDENDEEEYEAWK;SLAALDALNT(1)DDENDEEEYEAWK ;; 149.16 4.15E-06 104962700 26506.2 21881.2 22941.9 25071.4 23329.9 31196 23844.4 22574.5 27650.1 23779.7 TRUE FALSE FALSE 24408.2063 23772.51343 23792.147 24967.66119 23051.70618 24725.59795 24513.40969 29457.36113 24616.95321 24606.0428 0.991959841 0.966125013 0.96692293 1.014696324 0.936831101 1.004858772 0.996235351 1.197159631 1.000443403 1 14.58672504 -4.260250968 5.455408957 0.989761363 1.205070545 0.889510584 0.022262441 0.033583798 3.750354557 0.002929083 0.026855606 5.49E-05 4.260250968 0.215309182 SLADELALVDVLEDKLK ddPTM_HeLa_Curcumin_4h_R1 2 SLADELALVDVLEDKLK 17 1 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;C9J7H8;F5H793 A0A5F9ZHM4 LDHB L-lactate dehydrogenase B chain;L-lactate dehydrogenase 0 0 ; ; 197.73 5.12E-08 69350000 2921 2356.55 2979.5 2499.1 2264.09 3770.8 2910.9 2535.7 3007 2602.2 FALSE FALSE TRUE 2689.799768 2560.239681 3089.922891 2488.759386 2237.092205 2988.693574 2992.57202 3308.823257 2677.139623 2692.626256 0.998950286 0.950833661 1.147549863 0.924286978 0.830821656 1.109954851 1.111395246 1.228846094 0.994248503 1 11.39479828 -5.019349858 21.69304627 0.990833844 1.155259609 0.497021737 0.079807843 85.32731562 95662.34449 0.01084742 0.028257186 9.56E-06 5.019349858 0.164425765 SLANGT(ph)PPMGAASK ddPTM_HeLa_Curcumin_4h_R1 1 SLANGTPPMGAASK 14 0 A0A1B0GV68 A0A1B0GV68 1 0 SLANGT(0.856)PPMGAAS(0.144)K 81.525 0.0077755 0 3432.6 2320.7 2482.7 3093.6 2757.9 5112.3 2438.9 840.01 3492.4 2086.1 TRUE FALSE FALSE 3160.906088 2521.290967 2574.711046 3080.799503 2725.013844 4051.951353 2507.32897 1096.125182 3109.292458 2158.59182 1.464337101 1.168025814 1.192773466 1.427226526 1.262403489 1.877127169 1.16155771 0.507796412 1.440426314 1 11.07587475 -9.565569571 1.341372831 0.999989791 1.300203394 0 0.351424328 0.833262697 2.68697262 0.225601164 0.05300904 2.72E-10 9.565569571 0.300213603 SLAPDRS(ph)DDEHDPLDNTSRPR ddPTM_HeLa_Curcumin_4h_R1 3 SLAPDRSDDEHDPLDNTSRPR 21 2 Q92614;A0A0D9SFK2;Q92614-2;Q92614-3;Q92614-4;Q92614-5 Q92614 MYO18A Unconventional myosin-XVIIIa 1 0 S(0.26)LAPDRS(0.74)DDEHDPLDNTSRPR;S(0.01)LAPDRS(0.973)DDEHDPLDNT(0.008)S(0.008)RPR;S(0.011)LAPDRS(0.987)DDEHDPLDNT(0.001)S(0.001)RPR ;; 59.733 0.0035591 169064000 4281.5 4557.6 4681.2 3910.1 4176.2 5272.2 3851.6 2936.06 4331.4 4134.8 TRUE FALSE FALSE 3942.614757 4951.538636 4854.68939 3893.921042 4126.401543 4178.68629 3959.66553 3831.251178 3856.256257 4278.483992 0.921498074 1.157311479 1.134675132 0.910117006 0.964454127 0.976674518 0.925483311 0.895469326 0.901313704 1 12.06288398 -4.515442536 1.114474188 0.987520699 0.870759536 0.146960787 0.082926186 2.063559849 2.745086172 0.013279196 0.252351638 3.05E-05 4.515442536 -0.116761163 SLAQAEAEK ddPTM_HeLa_Curcumin_4h_R1 1 SLAQAEAEK 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 96.665 0.013345 1846500 596.8 370.11 525.25 693.52 509.86 828.09 498.54 395.32 663.93 535.34 FALSE FALSE TRUE 549.5626503 402.1006592 544.7162271 690.650398 503.7802525 656.3347995 512.5276906 515.8512482 591.0985401 553.9430252 0.992092373 0.725888117 0.983343417 1.246789591 0.909444166 1.184841707 0.92523539 0.931235208 1.067074615 1 9.113593788 -6.496928965 24.94903312 0.970108525 1.042114611 0.088955287 0.132756218 1670.997561 1606556.847 0.019504919 0.029725867 3.18E-07 6.496928965 0.072006086 SLASEAPSQPSLNGGS(ph)PEGVESQDGVDHFR ddPTM_HeLa_Curcumin_4h_R1 3 SLASEAPSQPSLNGGSPEGVESQDGVDHFR 30 0 P38935 P38935 IGHMBP2 DNA-binding protein SMUBP-2 1 0 SLASEAPS(0.004)QPS(0.19)LNGGS(0.805)PEGVESQDGVDHFR;SLASEAPSQPS(0.012)LNGGS(0.988)PEGVES(0.001)QDGVDHFR;SLAS(0.001)EAPS(0.01)QPS(0.129)LNGGS(0.813)PEGVES(0.047)QDGVDHFR ;; 94.927 3.49E-08 29310100 5554.2 4352.7 4527.91 4749.2 5335 6583.7 4339.88 3637.58 5760.1 4718.6 TRUE FALSE FALSE 5114.579209 4728.927993 4695.718328 4729.549069 5271.383609 5218.166406 4461.645353 4746.661397 5128.231441 4882.570999 1.047517632 0.968532356 0.96173068 0.968659559 1.079632761 1.068733339 0.913790164 0.972164337 1.050313747 1 12.25342531 -7.259609694 24.99216941 1.022438881 0.992010619 0.124195561 0.048988939 376.0566339 5136659.583 0.008771053 0.010443855 5.50E-08 7.259609694 -0.030428262 SLAVPTIEELEDEEERNHR ddPTM_HeLa_Curcumin_4h_R1 1 SLAVPTIEELEDEEERNHR 19 1 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 0 0 102.29 0.00037363 1195500 634.94 655.5 459.73 491.06 591.29 770.67 519.91 328.52 629.39 483.56 FALSE FALSE TRUE 584.683829 712.1584991 476.7679982 489.0281238 584.2392529 610.8243548 534.4972753 428.6842357 560.3474917 500.363674 1.168517739 1.423281777 0.952842948 0.977345377 1.167629233 1.220760792 1.068217585 0.856745319 1.11988044 1 8.966833245 SLDDDLDGVPLDATEDSK ddPTM_HeLa_Curcumin_4h_R1 1 SLDDDLDGVPLDATEDSK 18 0 O15042-2;O15042;O15042-3;E7ET15;H7C4V2 O15042-2 U2SURP U2 snRNP-associated SURP motif-containing protein 0 0 183.41 1.63E-19 0 1287.5 897.86 971.16 1066.4 1231.9 1067.6 904.19 1096.6 1051.7 771.25 FALSE FALSE TRUE 1185.593016 975.4670176 1007.152044 1061.987519 1217.210397 846.1677257 929.5591379 1430.948292 936.3311412 798.0508801 1.485610813 1.222311812 1.262014828 1.330726581 1.525229064 1.060292955 1.164786809 1.793053961 1.173272487 1 9.640336919 -9.464452832 1.14263335 0.995639754 1.351388759 0.202959777 0.20328462 0.489070495 1.119546806 0.140731639 0.033020114 3.43E-10 9.464452832 0.355749005 SLDGAAAVDSADRS(ph)PRPTSAPAITQGQVAEGGVLDASAK ddPTM_HeLa_Curcumin_4h_R1 2 SLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAK 39 2 A0A2R8Y4N6;A0A2R8YD30;A0A2U3TZH6;A0A3B3IU06;A0A2R8Y5Z6;A0A2R8Y5G2;A0A2R8Y570;A0A2R8YCW8;A0A2R8Y6G5;A0A3B3ITP0;A0A2R8YFR9;Q4VB86;A0A3B3IUD6;A0A2R8Y7Y3;A0A2R8Y7N0;A0A2R8Y420;P11171-3;P11171-7;P11171-5;P11171-4;P11171-6;P11171-2;P11171 A0A2R8Y4N6 EPB41 Protein 4.1 1 0 S(0.19)LDGAAAVDS(0.12)ADRS(0.421)PRPT(0.129)S(0.129)APAIT(0.011)QGQVAEGGVLDASAK;S(0.137)LDGAAAVDS(0.035)ADRS(0.237)PRPT(0.237)S(0.237)APAIT(0.118)QGQVAEGGVLDASAK ; 53.631 0.00023125 45575000 4956.8 3873.1 4000.4 4111.8 4774.6 3543.6 2398.52 1666.28 4612.9 3511.3 TRUE FALSE FALSE 4564.46405 4207.873506 4148.658343 4094.786461 4717.666013 2808.617415 2465.816016 2174.321101 4106.876411 3633.317414 1.256280014 1.158135397 1.141837575 1.127010386 1.298445876 0.773017355 0.678667932 0.598439622 1.13033791 1 11.82707169 -5.105137417 4.481796428 1.138266122 0.655137183 0.880816416 0.0806974 0.072935871 2.401826853 0.015479977 0.041929763 7.85E-06 5.105137417 -0.483128939 SLDGAAAVDSADRSPRPTS(ph)APAITQGQVAEGGVLDASAK ddPTM_HeLa_Curcumin_4h_R1 1 SLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAK 39 2 A0A2R8Y4N6;A0A2R8YD30;A0A2U3TZH6;A0A3B3IU06;A0A2R8Y5Z6;A0A2R8Y5G2;A0A2R8Y570;A0A2R8YCW8;A0A2R8Y6G5;A0A3B3ITP0;A0A2R8YFR9;Q4VB86;A0A3B3IUD6;A0A2R8Y7Y3;A0A2R8Y7N0;A0A2R8Y420;P11171-3;P11171-7;P11171-5;P11171-4;P11171-6;P11171-2;P11171 A0A2R8Y4N6 EPB41 Protein 4.1 1 0 S(0.018)LDGAAAVDS(0.018)ADRS(0.021)PRPT(0.211)S(0.519)APAIT(0.211)QGQVAEGGVLDAS(0.002)AK 43.118 0.004382 14568000 1981.8 1594.7 1621.6 1514.2 1749.3 2309.9 1575 748.46 1817.4 1525.2 TRUE FALSE FALSE 1824.938439 1732.538762 1681.697923 1507.934642 1728.44074 1830.800702 1619.190261 976.6620085 1618.035767 1578.200586 1.15634125 1.097793764 1.065579329 0.955477177 1.095197122 1.160055773 1.025972411 0.618845296 1.025240886 1 10.62406487 -4.268860288 4.145276885 1.07467319 0.584293271 0.828160305 0.061140814 0.073094969 2.75679156 0.010018104 0.105154928 5.38E-05 4.268860288 -0.490379919 SLDLFNCEVTNLNDYR ddPTM_HeLa_Curcumin_4h_R1 1 SLDLFNCEVTNLNDYR 16 0 P39687;H0YN26;Q92688-2;Q92688 P39687;Q92688-2 ANP32A;ANP32B Acidic leucine-rich nuclear phosphoprotein 32 family member A;Acidic leucine-rich nuclear phosphoprotein 32 family member B 0 0 160.46 0.002239 19555000 1050.6 922.47 1052.9 907.15 1117 1408 1339 1121.2 730.82 735.34 FALSE FALSE TRUE 967.4439014 1002.204196 1091.9214 903.3964537 1103.680505 1115.964929 1376.568736 1463.048719 650.6508744 760.8930103 1.271458521 1.317142072 1.435052478 1.187284469 1.450506825 1.466651571 1.809148879 1.922804782 0.8551148 1 9.571549799 -1 0.212784946 1.029490006 5.604887222 0.852617593 0.119342504 12.62204173 0.148931108 0.087570512 19.79943566 0.1 1 4.575397216 SLDNNYST(ph)PNER ddPTM_HeLa_Curcumin_4h_R1 1 SLDNNYSTPNER 12 0 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-25;O60716-26;O60716-27;O60716-29;H0YC95 O60716 CTNND1 Catenin delta-1 1 0 SLDNNYS(0.003)T(0.997)PNER 164.22 0.00034229 52162000 6050.2 6599.5 7013.5 7669.3 5037.2 6750.8 6855.6 4398.4 7400 7219.1 TRUE FALSE FALSE 5571.320286 7169.931373 7273.42648 7637.566469 4977.13468 5350.607983 7047.949685 5739.451912 6588.238514 7469.963188 0.745829684 0.959834901 0.973689735 1.022436962 0.666286373 0.716283046 0.943505277 0.768337376 0.881963987 1 12.86688542 -5.759529484 24.99999913 0.900548824 0.781644632 0.344332649 0.100921144 71.41787814 934814.5366 0.018492648 0.035536207 1.74E-06 5.759529484 -0.118904192 SLDS(ph)DES(ph)EDEEDDYQQK ddPTM_HeLa_Curcumin_4h_R1 3 SLDSDESEDEEDDYQQK 17 0 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 2 0 S(0.025)LDS(0.974)DES(0.999)EDEEDDY(0.002)QQK;S(0.092)LDS(0.908)DES(1)EDEEDDYQQK;S(0.01)LDS(0.99)DES(0.996)EDEEDDY(0.003)QQK ;; 124.82 0.00094966 129661800 9168.6 7478.4 7939.9 7882.9 8085.7 9617.5 7596.9 7731.2 9157.4 7534.4 TRUE FALSE FALSE 8442.895635 8124.799573 8234.159679 7850.282648 7989.283308 7622.722088 7810.048568 10088.40729 8152.856131 7796.219839 1.082947353 1.042146032 1.056173357 1.00693449 1.024763728 0.977745913 1.001773774 1.294012675 1.045744771 1 12.92855906 SLDS(ph)DES(ph)EDEEDDYQQKR ddPTM_HeLa_Curcumin_4h_R1 4 SLDSDESEDEEDDYQQKR 18 1 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 2 0 S(0.035)LDS(0.965)DES(0.976)EDEEDDY(0.025)QQKR;S(0.052)LDS(0.949)DES(0.999)EDEEDDYQQKR;S(0.126)LDS(0.869)DES(0.977)EDEEDDY(0.028)QQKR;S(0.118)LDS(0.874)DES(0.957)EDEEDDY(0.051)QQKR ;;; 86.258 0.0017144 986930000 16108.9 12997.2 14037.1 14080.2 14636.8 17409.9 13795.8 15426 17178.7 14304.39 TRUE FALSE FALSE 14833.86357 14120.62005 14557.32727 14021.93986 14462.26572 13798.89049 14182.87302 20129.31639 15294.23959 14801.46649 1.002188775 0.95400142 0.983505742 0.947334501 0.9770833 0.93226509 0.958207285 1.359954191 1.033292181 1 13.8534525 -4.258967802 24.99991027 0.984846331 1.359954323 0.937569928 0.029618293 39.66754926 401211.4676 0.004195647 0.037892506 5.51E-05 4.258967802 0.375107992 LNHVAAGLVS(ph)PSLK ddPTM_HeLa_Curcumin_4h_R1 2 LNHVAAGLVSPSLK 14 0 Q5T757;Q05519-2;Q05519;Q5T760 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 0 LNHVAAGLVS(0.5)PS(0.5)LK;LNHVAAGLVS(1)PSLK ; 174.39 0.00019187 400490000 6381.3 5070.8 5374 5619.7 6250.1 8293.5 8311.3 15048.8 5906 4922.8 TRUE FALSE FALSE 5876.213371 5509.097357 5573.165167 5596.44717 6175.57164 6573.334613 8544.492709 19637.10984 5258.126576 5093.866934 1.153585959 1.081515758 1.094093199 1.098663794 1.212354331 1.290440975 1.677407914 3.855049631 1.032246552 1 12.31454556 -3.994820122 1.527435257 1.088178471 6.711438365 0.991715899 0.074881508 0.151115901 0.192561119 0.012583737 1.547472257 0.0001012 3.994820122 5.623259893 up SLDSDES(ph)EDEEDDYQQKR ddPTM_HeLa_Curcumin_4h_R1 2 SLDSDESEDEEDDYQQKR 18 1 Q13442 Q13442 PDAP1 28 kDa heat- and acid-stable phosphoprotein 1 0 SLDS(0.001)DES(0.999)EDEEDDYQQKR;S(0.104)LDS(0.395)DES(0.501)EDEEDDYQQKR ; 146.18 8.51E-05 55055000 4280.2 3100.5 3685 3855.8 3322.1 4630.1 3798.8 9077.3 3694.5 4180 TRUE FALSE FALSE 3941.417654 3368.493404 3821.569342 3839.845721 3282.486127 3669.765068 3905.384104 11844.92698 3289.222593 4325.254689 0.911256778 0.778796544 0.883547818 0.887773321 0.75891164 0.848450631 0.902925812 2.738550175 0.760469112 1 12.07856937 -4.261259964 24.99999951 0.912355304 2.738550714 0.975940613 0.08817142 1.579693323 219943.4696 0.01274854 0.09883778 5.48E-05 4.261259964 1.82619541 SLDSEPSVPSAAKPPS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 3 SLDSEPSVPSAAKPPSPEK 19 1 Q7Z3K3-5;Q7Z3K3-7;Q7Z3K3-2;Q7Z3K3-3;Q7Z3K3-6;Q7Z3K3 Q7Z3K3-5 POGZ Pogo transposable element with ZNF domain 1 0 SLDSEPSVPS(0.072)AAKPPS(0.928)PEK;SLDSEPSVPSAAKPPS(1)PEK;SLDSEPSVPSAAKPPS(1)PEK ;; 82.216 0.0017264 201256600 5230.1 4926.4 5399.5 5145.8 5750.45 5247.4 5051.5 3392.37 5533.06 4505.01 TRUE FALSE FALSE 4816.132066 5352.216064 5599.61022 5124.508043 5681.879639 4159.03009 5193.231495 4426.687996 4926.097161 4661.558762 1.033159145 1.148160162 1.201231285 1.09931212 1.218879763 0.892197289 1.11405471 0.949615402 1.056748914 1 12.18659674 -3.243380553 13.98802891 1.04907657 1.067137909 0 0.102845457 0 0 0.013671427 0 0.000570978 3.243380553 0.018061339 SLDSESIS(ph)PGDFHR ddPTM_HeLa_Curcumin_4h_R1 2 SLDSESISPGDFHR 14 0 Q52LW3;F8VWZ8 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 0 SLDSES(0.003)IS(0.997)PGDFHR;SLDSES(0.012)IS(0.988)PGDFHR ; 152.94 0.00020962 14558500 7826.6 5811.1 6238.4 6887.2 6526.7 8063.2 5946 4925.5 7971.7 5885.4 TRUE FALSE FALSE 7207.116351 6313.38559 6469.600592 6858.702591 6448.873365 6390.801429 6112.828757 6427.262276 7097.224454 6089.917212 1.183450628 1.036694814 1.06234623 1.126239053 1.058942698 1.049406947 1.00376221 1.055394031 1.165405737 1 12.5722069 -5.319504392 2.699539214 1.084985294 1.030761909 0.179163681 0.054493975 0.528313584 7.516675765 0.010250609 0.027210632 4.79E-06 5.319504392 -0.054223385 SLEAASEK ddPTM_HeLa_Curcumin_4h_R1 2 SLEAASEK 8 0 P67936;A0A2R8Y5V9;A0A2R8YGX3;A0A2R8YH90;A0A2R8YE05;P67936-2;K7ENT6;A0A2R8YEU4;A0A2R8YHD2;A0A5F9UN72;K7EPB9 P67936 TPM4 Tropomyosin alpha-4 chain 0 0 ; ; 101.6 0.011953 8293900 5150.2 6577.7 4252.4 3473 3204.8 4989.5 3704.2 4131.9 3536.2 4541.2 FALSE FALSE TRUE 4742.556236 7146.247078 4409.997685 3458.629646 3166.584853 3954.621457 3808.129883 5391.697289 3148.287707 4699.006362 1.00926789 1.520799618 0.938495789 0.736034255 0.673883925 0.841586742 0.810411732 1.147412213 0.669990093 1 12.19814001 -6.523907756 24.99965587 1.052107513 0.831419923 0.159478606 0.224621524 39.59369614 961911.0904 0.030289286 0.04304074 2.99E-07 6.523907756 -0.22068759 SLEDLQDEYDFK ddPTM_HeLa_Curcumin_4h_R1 2 SLEDLQDEYDFK 12 0 A0A669KB68;A0A669KB56;A0A669KBA4;A0A669KB53;P42224;D2KFR9;A0A669KB17;E7EPD2;A0A669KB75;A0A669KB52;J3KPM9;A0A669KBI6;P42224-2 A0A669KB68 STAT1 Signal transducer and activator of transcription 1-alpha/beta;Signal transducer and activator of transcription 0 0 ; ; 182.08 0.00066668 10080200 3734 2668.6 3073.1 2831 2984.7 3375.2 2621 2538.7 3510.4 3320.7 FALSE FALSE TRUE 3438.44996 2899.261893 3186.991789 2819.286072 2949.109402 2675.145474 2694.538206 3312.737943 3125.317903 3436.094078 1.000685628 0.843766738 0.927504229 0.820491526 0.858273765 0.778542558 0.784186389 0.964099896 0.909555394 1 11.74655382 -7.262814213 24.62011954 1.000323772 0.849984372 0.403863635 0.061385116 44.84431043 803056.4027 0.008794978 0.010351271 5.46E-08 7.262814213 -0.1503394 SLEDQVEMLR ddPTM_HeLa_Curcumin_4h_R1 1 SLEDQVEMLR 10 0 K7ELL7;P14314-2;P14314 K7ELL7 PRKCSH Glucosidase 2 subunit beta 0 0 153.08 0.0034242 7544500 1104.9 730.46 1147.9 1002.6 1111.4 1415.1 1250.3 649.12 1149.3 1054.8 FALSE FALSE TRUE 1017.445999 793.5977075 1190.442184 998.4515069 1098.147281 1121.592309 1285.380053 847.0336998 1023.224665 1091.454221 0.932193013 0.727101231 1.090693646 0.914790091 1.00613224 1.027612782 1.17767656 0.776059759 0.937487478 1 10.09203591 -5.637017156 8.125564139 0.954102917 1.012891994 0.037113491 0.125722159 0.64585004 43.51848811 0.017111546 0.034287765 2.31E-06 5.637017156 0.058789077 SLEESQGK ddPTM_HeLa_Curcumin_4h_R1 1 SLEESQGK 8 0 E5RI30;O75330-4;O75330-2;O75330;O75330-3 E5RI30 HMMR Hyaluronan mediated motility receptor 0 0 145.04 4.38E-05 0 2779.7 2269.5 3162.7 3717.4 3394 4000 3446 3994.3 3316.3 3092.9 FALSE FALSE TRUE 2559.683812 2465.665467 3279.912444 3702.018384 3353.528767 3170.354911 3542.685486 5212.143683 2952.510187 3200.378045 0.799806703 0.770429441 1.024851564 1.156744088 1.047853947 0.990618879 1.106958439 1.628602499 0.922550444 1 11.64402662 -1 0.712033861 0.917272825 93.80026772 0.767564879 0.109177154 115.3971409 0.545278967 0.02130997 17120.62723 0.1 1 92.8829949 SLENETLNKEEDCHS(ph)PTSKPPKPDQPLK ddPTM_HeLa_Curcumin_4h_R1 4 SLENETLNKEEDCHSPTSKPPKPDQPLK 28 3 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 SLENET(0.009)LNKEEDCHS(0.33)PT(0.33)S(0.33)KPPKPDQPLK;SLENETLNKEEDCHS(0.644)PT(0.178)S(0.178)KPPKPDQPLK;S(0.001)LENET(0.005)LNKEEDCHS(0.783)PT(0.106)S(0.106)KPPKPDQPLK;SLENETLNKEEDCHS(0.924)PT(0.038)S(0.038)KPPKPDQPLK ;;; 89.272 8.96E-07 770213000 14091.9 10155.6 11110.5 11858.2 13867.4 19478.5 14911.4 16371.5 13941.5 12013.8 TRUE FALSE FALSE 12976.51125 11033.40481 11522.2649 11809.13391 13702.04031 15438.43953 15329.77375 21363.09498 12412.15233 12431.27866 1.043859735 0.887551886 0.92687689 0.949953278 1.102222924 1.241902781 1.233161461 1.718495384 0.998461435 1 13.60168708 -2.853735646 0.723056483 0.999724619 6.47300799 0.9134538 0.068390883 3.75720256 0.284337888 0.012168242 26.59384641 0.00140044 2.853735646 5.473283371 SLENPTPPFT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SLENPTPPFTPK 12 0 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 0 SLENPTPPFT(1)PK 143.58 0.0028299 8241300 4601.2 3295.6 4192.2 4312.4 4614.6 4583.4 3371 2631.9 4755.7 3335.9 TRUE FALSE FALSE 4237.010165 3580.456979 4347.56662 4294.556431 4559.573909 3632.751174 3465.581187 3434.354194 4234.011608 3451.822277 1.227470543 1.037265737 1.259498975 1.244141815 1.320917922 1.052415473 1.003985985 0.994939461 1.226601855 1 11.75314247 -5.011912894 23.92214638 1.140633019 1.006647142 0.315332083 0.101431662 410.7323552 824797.6593 0.017186043 0.046730642 9.73E-06 5.011912894 -0.133985877 SLEPEES(ph)PGKR ddPTM_HeLa_Curcumin_4h_R1 3 SLEPEESPGKR 11 1 Q9BVI0;Q5JWZ0;Q5JXL1 Q9BVI0 PHF20 PHD finger protein 20 1 0 SLEPEES(1)PGKR;SLEPEES(1)PGKR;SLEPEES(1)PGKR ;; 74.649 0.016075 152137000 6805.5 6525.9 7095.7 6679 7131.9 8953.7 6548.8 3078.13 8444.9 6926.8 TRUE FALSE FALSE 6266.837494 7089.969717 7358.672884 6651.364068 7046.85675 7096.601691 6732.541703 4016.637667 7518.515598 7167.505784 0.874340068 0.98918228 1.026671356 0.927988657 0.983167222 0.990107564 0.939314443 0.560395455 1.04897238 1 12.80725545 -4.262098904 5.604513676 0.954220321 0.547041807 0.849734447 0.051714453 0.04317623 5.454832776 0.007600562 0.067037948 5.47E-05 4.262098904 -0.407178515 SLESINS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 SLESINSR 8 0 P62888;A0A0C4DH44;E5RI99;E5RJH3 P62888 RPL30 60S ribosomal protein L30 1 0 SLES(0.001)INS(0.999)R;SLESINS(1)R ; 98.04 0.0162 22143000 3595 2920.9 3284.9 3543.2 3626.1 5359.6 5118.1 4073.7 4124.8 3819.8 TRUE FALSE FALSE 3310.451957 3173.369581 3406.641284 3528.539177 3582.861126 4247.958545 5261.700111 5315.752377 3672.31976 3952.537766 0.837551 0.802868883 0.861887093 0.892727505 0.906471067 1.074742051 1.331220705 1.344896037 0.929104281 1 11.94856353 -4.915069275 2.296851601 0.904015456 1.356606861 0.920328915 0.052337799 0.083879994 0.863407191 0.010820413 0.044897782 1.22E-05 4.915069275 0.452591405 SLESINSR ddPTM_HeLa_Curcumin_4h_R1 1 SLESINSR 8 0 P62888;A0A0C4DH44;E5RI99;E5RJH3 P62888 RPL30 60S ribosomal protein L30 0 0 160.11 4.23E-06 7021600 1920.7 1424.2 1511.6 1486.4 1598.3 2018.4 1472.6 1621.9 1556.3 1575.8 FALSE FALSE TRUE 1768.674568 1547.301502 1567.621226 1480.249671 1579.241316 1599.761088 1513.917193 2116.409844 1385.577784 1630.558933 1.084704473 0.94893933 0.961401146 0.907817339 0.968527592 0.981112093 0.92846518 1.29796587 0.849756336 1 10.67115087 -4.251872624 24.85340563 1.006354434 1.297966039 0.607070389 0.073391903 616.4423126 1601416.089 0.009471584 0.162681857 5.60E-05 4.251872624 0.291611605 SLESLADGGS(ph)ASPIKDQPVMAVK ddPTM_HeLa_Curcumin_4h_R1 4 SLESLADGGSASPIKDQPVMAVK 23 1 A0A3B3ITU7;Q9HB96 A0A3B3ITU7 FANCE Fanconi anemia group E protein 1 0 SLES(0.001)LADGGS(0.579)AS(0.42)PIKDQPVMAVK;SLES(0.002)LADGGS(0.53)AS(0.467)PIKDQPVMAVK;SLES(0.03)LADGGS(0.875)AS(0.095)PIKDQPVMAVK;SLES(0.001)LADGGS(0.578)AS(0.421)PIKDQPVMAVK ;;; 99.86 2.88E-05 153911000 7200.6 6047.6 6580.6 6637.2 6799.2 7279.7 5520.66 3395.98 7060 6807.52 TRUE FALSE FALSE 6630.664912 6570.327596 6824.482825 6609.737025 6718.123981 5769.808161 5675.554862 4431.398669 6285.535663 7044.080813 0.941310171 0.932744494 0.968825175 0.938339182 0.953726137 0.819100222 0.805719726 0.629095376 0.89231453 1 12.78219575 -3.521370164 0.596049796 0.971765066 2.25E-19 0.87953246 0.036293475 1.287633937 0.166506335 0.005302424 1.054159016 0.000301044 3.521370164 -0.971765066 SLETENAGLR ddPTM_HeLa_Curcumin_4h_R1 2 SLETENAGLR 10 0 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 128.6 0.0016457 31433000 5299.9 4150 4880.8 4793.9 4500.7 5639.5 4552.9 3967.5 5066.4 4619 FALSE FALSE TRUE 4880.407323 4508.707508 5061.686742 4774.064112 4447.032092 4469.80413 4680.64212 5177.172486 4510.628596 4779.509906 1.021110411 0.943340969 1.059038864 0.998860596 0.93043684 0.935201353 0.979314242 1.083201539 0.943742912 1 12.22264698 -5.985485022 24.99418549 1.008442771 0.976767184 0 0.051405261 459.0848089 790520.2401 0.006763193 0.012256321 1.03E-06 5.985485022 -0.031675587 SLETENRR ddPTM_HeLa_Curcumin_4h_R1 2 SLETENRR 8 1 P05783;F8VZY9;CON__P05784 P05783 KRT18 "Keratin, type I cytoskeletal 18" 0 0 ; ; 111.01 0.0017042 1629580 1459.07 2628.9 1007.76 1126.02 912.35 1509.5 1024.99 504.51 1210.41 1486.74 FALSE FALSE TRUE 1343.58307 2856.130402 1045.108472 1121.360828 901.4708221 1196.412684 1053.748461 658.3327765 1077.631051 1538.404104 0.8733616 1.85655407 0.679345868 0.72891175 0.58597791 0.777697278 0.684962071 0.42793228 0.700486334 1 10.5872188 -6.567728441 24.99999911 1.019668254 0.65366222 0.346298074 0.300268128 127.3838291 71005.49088 0.044734797 0.063264569 2.71E-07 6.567728441 -0.366006034 SLETSSALS(ph)PSLK ddPTM_HeLa_Curcumin_4h_R1 2 SLETSSALSPSLK 13 0 Q7Z333-3;Q7Z333;Q7Z333-4 Q7Z333-3 SETX Probable helicase senataxin 1 0 SLETSSALS(0.997)PS(0.003)LK;SLETS(0.001)S(0.015)ALS(0.655)PS(0.328)LK ; 197.38 2.61E-06 25368000 4814.8 3656.1 3997.7 3918.2 3914.9 5803.9 5276.5 1989.63 5174.8 3899 TRUE FALSE FALSE 4433.703499 3972.116993 4145.858279 3901.987527 3868.217374 4600.105717 5424.544389 2596.259028 4607.137387 4034.48996 1.098950188 0.984540061 1.027604064 0.967157575 0.958787211 1.140195108 1.344542791 0.643516046 1.141937998 1 11.97817058 -11.51982968 11.74896657 1.039493331 1.037546223 0 0.170348853 0 0 0 0.019642861 3.02E-12 11.51982968 -0.001947109 SLFS(ph)PQNTLAAPTGHPPTSGVEK ddPTM_HeLa_Curcumin_4h_R1 2 SLFSPQNTLAAPTGHPPTSGVEK 23 0 Q5VT52-2;Q5VT52-3;Q5VT52 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 S(0.05)LFS(0.755)PQNT(0.194)LAAPT(0.001)GHPPTSGVEK;S(0.095)LFS(0.558)PQNT(0.346)LAAPT(0.001)GHPPTSGVEK ; 91.079 8.23E-05 22194000 2996.94 2102.5 2413.46 2663.65 2937.92 4383.6 3231.61 2243.87 2578.13 2764.07 TRUE FALSE FALSE 2759.729037 2284.230731 2502.904951 2652.628522 2902.887223 3474.391947 3322.280279 2928.015633 2295.315589 2860.121227 0.964899323 0.798648222 0.875104498 0.927453178 1.014952512 1.214770868 1.161587225 1.023738297 0.802523882 1 11.48186058 -5.465366756 5.238586771 0.955522525 1.135153116 0.547523103 0.087698948 0.134783661 7.782315963 0.011752331 0.026370389 3.42E-06 5.465366756 0.179630591 SLFSNVVTK ddPTM_HeLa_Curcumin_4h_R1 1 SLFSNVVTK 9 0 P31939-2;P31939;H7C1S2 P31939-2 ATIC Bifunctional purine biosynthesis protein PURH;Phosphoribosylaminoimidazolecarboxamide formyltransferase;IMP cyclohydrolase 0 0 109.42 0.0038112 2412800 1912.4 1346.8 1568.2 1709 1741.3 1800.6 1818.3 1784 1986.7 1862.7 FALSE FALSE TRUE 1761.031522 1463.211391 1626.318872 1701.928611 1720.536135 1427.135263 1869.316604 2327.933387 1768.76398 1927.428686 0.913668835 0.759152025 0.843776417 0.883004711 0.892658777 0.740434794 0.969849944 1.207792228 0.917680635 1 10.91246177 -3.236876414 13.59554143 0.928518029 0.904461471 0 0.126391717 0 0 0.017003873 0 0.000579594 3.236876414 -0.024056558 SLFSPQNTLAAPT(ph)GHPPTSGVEK ddPTM_HeLa_Curcumin_4h_R1 1 SLFSPQNTLAAPTGHPPTSGVEK 23 0 Q5VT52-2;Q5VT52-3;Q5VT52 Q5VT52-2 RPRD2 Regulation of nuclear pre-mRNA domain-containing protein 2 1 0 S(0.01)LFS(0.075)PQNT(0.017)LAAPT(0.892)GHPPT(0.004)S(0.001)GVEK 63.936 0.0040533 24544000 1244.4 983.43 1029.7 1271.2 1242.5 2165.8 1565.2 1035.3 1455.4 1090.4 TRUE FALSE FALSE 1145.904427 1068.433307 1067.861588 1265.940111 1227.683999 1716.588666 1609.115299 1350.958204 1295.746261 1128.291319 1.015610426 0.946948088 0.946441376 1.121997564 1.088091328 1.521405543 1.426152335 1.197348753 1.148414633 1 10.1399239 -5.418884587 4.223527937 1.007331533 1.384499856 0.715016021 0.098943694 0.073446579 2.235831263 0.012345036 0.028444114 3.81E-06 5.418884587 0.377168323 SLGAWNLENLRS(ph)PEEVDKESQR ddPTM_HeLa_Curcumin_4h_R1 2 SLGAWNLENLRSPEEVDKESQR 22 2 P48681 P48681 NES Nestin 1 0 SLGAWNLENLRS(1)PEEVDKESQR;SLGAWNLENLRS(1)PEEVDKESQR ; 62.167 0.0023277 35664100 2858.7 2325.2 2250.04 2731.27 2428.7 3152.3 2900.1 2585.3 2763 2496.2 TRUE FALSE FALSE 2632.430879 2526.179927 2333.428462 2719.968728 2399.739339 2498.477446 2981.469001 3373.546069 2459.905813 2582.942764 1.019159586 0.978023966 0.903399214 1.053050329 0.929071821 0.967298804 1.154291548 1.306086265 0.952365591 1 11.33479996 -4.516015336 2.862129175 0.994720478 1.30142643 0.843350407 0.045465275 0.080192497 1.192731789 0.006186717 0.042954821 3.05E-05 4.516015336 0.306705952 SLGDDISSETSGDFR ddPTM_HeLa_Curcumin_4h_R1 2 SLGDDISSETSGDFR 15 0 P12429;D6RA82;D6RFG5 P12429 ANXA3 Annexin A3;Annexin 0 0 ; ; 216.91 2.32E-13 18706800 2465.7 2114.2 2469 2514.9 2473.2 2570.64 2617.6 3259.1 2606.03 2185.9 FALSE FALSE TRUE 2270.537243 2296.942027 2560.503312 2504.49401 2443.708705 2037.460287 2691.042811 4252.784587 2320.155029 2261.859862 1.003836392 1.015510318 1.132034462 1.107271963 1.080397927 0.900789797 1.189747807 1.880215772 1.025773112 1 11.14329383 -4.283130743 3.099194752 1.01996026 1.991498097 0.940170665 0.063717041 0.054491277 0.806512687 0.009133724 0.125277645 5.21E-05 4.283130743 0.971537837 SLGDDISSETSGDFRK ddPTM_HeLa_Curcumin_4h_R1 2 SLGDDISSETSGDFRK 16 1 P12429;D6RA82;D6RFG5 P12429 ANXA3 Annexin A3;Annexin 0 0 ; ; 147.51 0.00052981 19858100 1913.49 1658.25 1735.9 2112.72 1911.18 2087.53 1890.11 1868.89 2061.72 2076.1 FALSE FALSE TRUE 1762.035247 1801.581741 1800.233981 2103.978124 1888.390427 1654.552747 1943.1414 2438.705958 1835.554474 2148.24432 0.820221066 0.838629817 0.838002439 0.979394245 0.879038948 0.770188349 0.904525328 1.135208847 0.854444002 1 11.06894237 -4.264217298 6.290159124 0.894776428 1.140394939 0.546626285 0.068979054 0.091344747 19.8928674 0.011822289 0.095956198 5.44E-05 4.264217298 0.245618512 SLGEKS(ph)PAASGAR ddPTM_HeLa_Curcumin_4h_R1 1 SLGEKSPAASGAR 13 1 O75683 O75683 SURF6 Surfeit locus protein 6 1 0 SLGEKS(0.996)PAAS(0.003)GAR 67.299 0.01731 34330000 6191.3 5447.9 5002.1 5463.6 5518.9 8838.4 8256.2 3057 6143.1 3945.7 TRUE FALSE FALSE 5701.252072 5918.792201 5187.482226 5440.993071 5453.090722 7005.216211 8487.846752 3989.065227 5469.217299 4082.812781 1.396403014 1.44968494 1.270565785 1.332657989 1.335621057 1.715781885 2.078921373 0.977038488 1.339570926 1 11.9953477 -11.72978852 0.151173532 1.29E-11 1.662868859 0.082124328 0.292174538 33.42685871 0.575829556 11.2561149 0.714900757 1.86E-12 11.72978852 1.662868859 SLGGIS(ph)PSEDR ddPTM_HeLa_Curcumin_4h_R1 1 SLGGISPSEDR 11 0 H3BMM1;H3BV44;H3BRD5;B2RTY4-5;B2RTY4-2;B2RTY4;B2RTY4-4 H3BMM1 MYO9A Unconventional myosin-IXa 1 0 SLGGIS(0.831)PS(0.169)EDR 126.66 0.0033323 3015800 2053.8 2016.5 2018.9 1829.7 2191.1 2107 1540.2 1172 2238.6 1726.2 TRUE FALSE FALSE 1891.239563 2190.797275 2093.72221 1822.129186 2164.972564 1669.984449 1583.413867 1529.337405 1993.031181 1786.185322 1.058814861 1.226522942 1.172175241 1.020123256 1.212064917 0.934944672 0.88647793 0.856203097 1.115803135 1 10.80266606 -5.031261733 12.22529327 1.065141564 0.881135522 0.564796388 0.082833302 0.980051027 383.578358 0.012922345 0.03336849 9.31E-06 5.031261733 -0.184006042 AGHPPAVK(ac)AGGMR ddPTM_HeLa_Curcumin_4h_R1 3 AGHPPAVKAGGMR 13 1 P51397;B4DQ75 P51397 DAP Death-associated protein 1 0 1 ;; AGHPPAVK(1)AGGMR;AGHPPAVK(1)AGGMR;AGHPPAVK(1)AGGMR 104.07 0.0046465 9293900 856.34 693.96 743.73 851.88 666.05 681.6 591.743 227.38 1028.69 903.827 FALSE TRUE FALSE 788.5597854 753.9428102 771.2932881 848.3551463 658.1077888 540.2284768 608.345716 296.7071153 915.8452807 935.234921 0.843167602 0.806153399 0.824705398 0.907103795 0.703681796 0.577639334 0.650473696 0.317254102 0.979267626 1 9.86918499 -4.197091703 0.363619251 0.948372314 1.09E-26 0.853067615 0.075211345 1.831770701 0.16183962 0.025083007 0.767026849 6.35E-05 4.197091703 -0.948372314 SLGKDGS(ph)LEDDEDEEDDLDEGVGGK ddPTM_HeLa_Curcumin_4h_R1 1 SLGKDGSLEDDEDEEDDLDEGVGGK 25 1 Q12789-3;Q12789 Q12789-3 GTF3C1 General transcription factor 3C polypeptide 1 1 0 S(0.045)LGKDGS(0.955)LEDDEDEEDDLDEGVGGK 76.796 0.00012634 43026000 2290.7 1495.9 2054.6 2186.6 1765.1 2188.1 1557.9 1023.9 2449.6 2110.9 TRUE FALSE FALSE 2109.388678 1625.19893 2130.745283 2177.552429 1744.052335 1734.263395 1601.610481 1336.082397 2180.885009 2184.253618 0.965725161 0.744052301 0.975502692 0.996932046 0.798466039 0.793984444 0.733252983 0.611688307 0.998457776 1 11.09292466 -3.241416453 0.331016803 0.991212585 1.55E-12 0.68484875 0.075592899 5.141642169 0.238353488 0.026065482 2.345045765 0.000573566 3.241416453 -0.991212585 SLGLSLS(ph)GGDQEDAGR ddPTM_HeLa_Curcumin_4h_R1 1 SLGLSLSGGDQEDAGR 16 0 H0YE82;H7C1L7;H0YEB7;C9JEV6;H7C3G9;Q9UJ70;Q9UJ70-2 H0YE82 NAGK N-acetyl-D-glucosamine kinase 1 0 SLGLS(0.317)LS(0.683)GGDQEDAGR 161.48 0.0002536 43969000 2567.3 2312.1 2366.8 2538.3 2350.9 3078.4 2131.7 2337.1 2876.2 2403.9 TRUE FALSE FALSE 2364.095496 2511.947621 2454.51569 2527.797187 2322.867053 2439.905139 2191.509765 3049.671031 2560.688056 2487.435346 0.950414852 1.009854437 0.986765623 1.016226288 0.933840173 0.980891883 0.88103185 1.226030271 1.029449091 1 11.28044331 -4.247909936 24.99404921 0.974347942 1.226030437 0.758522546 0.042222346 750.2998766 1386067.771 0.005165406 0.136219944 5.65E-05 4.247909936 0.251682495 SLGLWTTSPESSS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SLGLWTTSPESSSR 14 0 H0YEJ7;E9PJK4;A6NI28 H0YEJ7 ARHGAP42 Rho GTPase-activating protein 42 1 0 SLGLWT(0.002)T(0.002)S(0.009)PES(0.002)S(0.212)S(0.774)R 119.17 0.0018588 3094900 942.55 848.5 946.06 1004.6 894.94 814.35 812.92 713.87 911.09 803.99 TRUE FALSE FALSE 867.9461729 921.8405592 981.1218158 1000.443231 884.268425 645.4446304 835.7283473 931.5256767 811.1457064 831.9285927 1.043294077 1.108076543 1.179334169 1.202559018 1.062913852 0.775841384 1.004567405 1.119718309 0.975018425 1 9.700315892 -4.246714017 22.284681 1.035131594 1.119718542 0.042738521 0.113136722 1620.049115 2451508.636 0.016159541 0.405539069 5.67E-05 4.246714017 0.084586947 SLGNILQAKPTS(ph)SPAKGPPQK ddPTM_HeLa_Curcumin_4h_R1 2 SLGNILQAKPTSSPAKGPPQK 21 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 SLGNILQAKPT(0.102)S(0.449)S(0.449)PAKGPPQK;SLGNILQAKPT(0.284)S(0.421)S(0.294)PAKGPPQK ; 88.504 0.00026277 1502640000 10274.7 8284.1 9559 9740.2 8248.4 11022.7 9550.5 5426.9 11098.9 8730.8 TRUE FALSE FALSE 9461.446653 9000.140691 9913.264949 9699.897633 8150.043217 8736.467769 9818.461326 7081.536828 9881.378438 9034.19465 1.04729276 0.996230548 1.097304777 1.073687031 0.902132789 0.967044447 1.086810912 0.783859226 1.093775242 1 13.14118028 -5.762462392 24.99999912 1.030134835 0.948099821 0.321419627 0.078420866 31.02449307 758199.1193 0.0104386 0.019734604 1.73E-06 5.762462392 -0.082035014 SLGNILQAKPTSS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 2 SLGNILQAKPTSSPAK 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 SLGNILQAKPT(0.067)S(0.286)S(0.647)PAK;SLGNILQAKPT(0.013)S(0.068)S(0.919)PAK ; 90.896 0.0023049 583850000 9763.7 7563.4 9720.4 8602.3 10815.2 9946.2 10393.2 5571.2 8375.3 6938.1 TRUE FALSE FALSE 8990.892842 8217.146594 10080.64657 8566.705962 10686.2358 7883.246003 10684.80522 7269.833233 7456.550544 7179.198459 1.252353295 1.144577162 1.404146526 1.193267746 1.488499847 1.098067709 1.488300579 1.012624637 1.038632737 1 12.80960706 -9.08542867 0.526976205 0.959360266 1.280281866 0.284978195 0.15219929 1.098351249 0.467073605 0.176092625 0.035008913 8.21E-10 9.08542867 0.3209216 SLGNILQAKPTSSPAK(ac)GPPQK ddPTM_HeLa_Curcumin_4h_R1 1 SLGNILQAKPTSSPAKGPPQK 21 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 0 1 SLGNILQAKPTSSPAK(1)GPPQK 201.61 3.50E-16 3106800 1763.9 1467.6 1380.8 1293.5 1198.8 1908.7 1708.4 1146.9 1787.5 1612.6 FALSE TRUE FALSE 1624.285454 1594.452805 1431.973663 1288.14784 1184.505093 1512.814105 1756.333106 1496.58453 1591.415722 1668.63773 0.973420069 0.955541623 0.858169294 0.771975736 0.709863544 0.906616264 1.052555072 0.896890022 0.953721526 1 10.70445506 -6.874435912 3.635013683 0.986635458 0.864890654 0.265426882 0.085001348 0.236659177 6.046991283 0.015228626 0.020410807 1.34E-07 6.874435912 -0.121744804 SLGRSAGTS(ph)PPS(ph)S(ph)GASPKAGQS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SLGRSAGTSPPSSGASPKAGQSK 23 2 B7WPD9;A0A0G2JR66;Q2KJY2-2;Q2KJY2 B7WPD9 KIF26B Kinesin-like protein;Kinesin-like protein KIF26B 4 0 S(0.053)LGRS(0.169)AGT(0.518)S(0.631)PPS(0.635)S(0.871)GAS(0.127)PKAGQS(0.996)K 47.66 0.0084478 0 1504.4 1019.8 1216 1370 1408.7 1906.8 1277 1157.4 1562.2 1589.5 TRUE FALSE FALSE 1385.325153 1107.946968 1261.06603 1364.331303 1391.902173 1511.308186 1312.829183 1510.285932 1390.830568 1644.735007 0.842278633 0.673632508 0.766729002 0.829514358 0.846277465 0.918876402 0.798201034 0.918254871 0.845625929 1 10.68363945 -8.793430194 0.940718632 0.9891326 0.82344611 0.094574078 0.081171487 0.347306839 0.607760789 0.032734189 0.014308615 1.61E-09 8.793430194 -0.165686491 SLGS(ph)PLLHER ddPTM_HeLa_Curcumin_4h_R1 3 SLGSPLLHER 10 0 H7C3L4;E7EQA9;Q92844;E7EV32;E7EMT6;E7ENY2;E7EVA2;E7EW82 H7C3L4 TANK TRAF family member-associated NF-kappa-B activator 1 0 S(0.013)LGS(0.987)PLLHER;S(0.007)LGS(0.993)PLLHER;S(0.062)LGS(0.938)PLLHER ;; 92.039 0.0084389 13857900 5643.7 5245.9 5066.5 5146.7 5370.7 6029.6 4353.8 2758.31 5769.8 4735.3 TRUE FALSE FALSE 5196.99519 5699.332221 5254.268947 5125.404319 5306.65791 4778.992992 4475.95591 3599.306021 5136.867375 4899.851323 1.060643446 1.163164318 1.072332322 1.046032621 1.083024272 0.975334286 0.913488107 0.734574538 1.048372091 1 12.25852226 -4.319156002 1.343438611 1.04722351 0.624848478 0.843349567 0.04415991 0.41041137 0.688837726 0.007706016 0.228232504 4.80E-05 4.319156002 -0.422375031 SLGSAGPSGT(ph)LPR ddPTM_HeLa_Curcumin_4h_R1 1 SLGSAGPSGTLPR 13 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 0 SLGS(0.002)AGPS(0.022)GT(0.976)LPR 118.76 0.0075979 9944100 1449.4 1094.9 1695.4 1628.2 1544.8 2267.6 1591 1236 1755.2 1549.4 TRUE FALSE FALSE 1334.678461 1189.538277 1758.233015 1621.46294 1526.379269 1797.274199 1635.639178 1612.85071 1562.658951 1603.241535 0.832487452 0.741958246 1.096673818 1.011365352 0.952058212 1.121025223 1.020207587 1.005993592 0.974687168 1 10.64677607 -6.72512146 24.99975161 0.905266004 1.033028527 0.436629658 0.080916629 162.2237856 111667.7887 0.014697005 0.020784347 1.88E-07 6.72512146 0.127762522 SLGSVQAPS(ph)YGAR ddPTM_HeLa_Curcumin_4h_R1 1 SLGSVQAPSYGAR 13 0 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 S(0.206)LGS(0.292)VQAPS(0.496)Y(0.007)GAR 136.33 0.0012286 66817000 1365.2 1061.5 1179.7 1088.8 1169.9 2090.6 1217.7 491.07 1252.4 1169.6 TRUE FALSE FALSE 1257.142979 1153.25133 1223.42072 1084.294834 1155.949707 1656.985994 1251.865385 640.7949824 1115.014853 1210.243513 1.038752091 0.9529085 1.010888062 0.895931127 0.955138114 1.369134374 1.03439132 0.529476073 0.921314464 1 10.24108165 -4.260824486 24.99997577 1.025611876 0.529475921 0.579080965 0.125330599 26.25853528 1067356.436 0.016339076 0.13020338 5.48E-05 4.260824486 -0.496135955 SLGSVQAPSYGAR ddPTM_HeLa_Curcumin_4h_R1 2 SLGSVQAPSYGAR 13 0 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 0 0 ; ; 147.58 0.00031393 20232100 3683.5 2890.1 3197.4 3127.7 3376.8 4631.9 2905.4 2642.99 3281.7 2888.7 FALSE FALSE TRUE 3391.947088 3139.907366 3315.898457 3114.758406 3336.533865 3671.191728 2986.917705 3448.825484 2921.70572 2989.08211 1.134778826 1.05045872 1.109336691 1.042045113 1.116240285 1.228200361 0.999275896 1.153807543 0.977459171 1 11.54548681 -9.422607163 0.978988162 0.995546781 1.10454321 0.357608917 0.061206167 0.595719937 0.951596201 0.048461566 0.010362793 3.78E-10 9.422607163 0.108996428 SLGSVQAPSYGARPVSSAAS(ph)VYAGAGGSGSR ddPTM_HeLa_Curcumin_4h_R1 1 SLGSVQAPSYGARPVSSAASVYAGAGGSGSR 31 1 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 S(0.001)LGS(0.003)VQAPS(0.067)Y(0.168)GARPVS(0.087)S(0.177)AAS(0.386)VY(0.06)AGAGGS(0.026)GS(0.026)R 40.872 0.016175 24755000 317.78 149.62 160.81 292.91 239.48 475.3 143.24 294.41 316.98 239.21 TRUE FALSE FALSE 292.6273777 162.5524861 166.7697601 291.698016 236.6243574 376.7174223 147.2589289 384.1742537 282.208087 247.5225297 1.182225222 0.656717941 0.673755881 1.178470567 0.955970989 1.521952053 0.594931415 1.552077923 1.14013091 1 7.951416036 -4.214492457 22.96596053 1.033538651 1.552084022 0.259281003 0.276401508 15148.18419 7409821.756 0.035855695 27.426398 6.10E-05 4.214492457 0.518545371 SLGSVQAPSYGARPVSSAASVYAGAGGS(ph)GSR ddPTM_HeLa_Curcumin_4h_R1 2 SLGSVQAPSYGARPVSSAASVYAGAGGSGSR 31 1 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 SLGSVQAPSYGARPVSSAASVYAGAGGS(0.708)GS(0.292)R;SLGSVQAPSYGARPVSSAASVYAGAGGS(0.716)GS(0.284)R ; 99.151 8.83E-09 139716000 2273.3 1848.87 1709.86 2242.4 1481.95 3207.3 1816.66 959.58 2884.8 2042.96 TRUE FALSE FALSE 2093.365906 2008.678084 1773.228916 2233.121543 1464.278714 2542.069826 1867.63059 1252.151525 2568.344657 2113.952708 0.990261465 0.950200105 0.838821469 1.056372517 0.692673355 1.202519724 0.883477943 0.592327123 1.214948966 1 11.04572739 -4.31683921 3.834073456 0.976370019 0.57331312 0.396483374 0.147341797 0.134487117 3.538471169 0.015492332 0.134468814 4.82E-05 4.31683921 -0.403056898 SLGTADVHFER ddPTM_HeLa_Curcumin_4h_R1 2 SLGTADVHFER 11 0 Q86V81;E9PB61 Q86V81 ALYREF THO complex subunit 4 0 0 ; ; 139.76 0.0011171 21419300 9120.1 7807 7555.6 8531.6 8267.2 11742.2 9184.5 7691 10430.9 7951.2 FALSE FALSE TRUE 8398.234462 8481.802293 7835.617183 8496.2985 8168.619039 9306.735358 9442.192351 10035.95049 9286.656367 8227.503608 1.020751234 1.030908365 0.952368732 1.032670285 0.99284296 1.131173659 1.147637583 1.219805055 1.128733187 1 13.00623904 -5.00695284 1.771334301 1.007270949 1.198357902 0.657880974 0.047342462 0.085091028 0.498210164 0.003746442 0.01665882 9.84E-06 5.00695284 0.191086954 SLGVLPFT(ph)LNSGSPEK ddPTM_HeLa_Curcumin_4h_R1 1 SLGVLPFTLNSGSPEK 16 0 P42695 P42695 NCAPD3 Condensin-2 complex subunit D3 1 0 SLGVLPFT(0.611)LNS(0.032)GS(0.357)PEK 106.01 0.0055942 116630000 1144.8 968.28 1139.2 1175.1 898.76 1192.6 1115.6 566.21 953.13 962.69 TRUE FALSE FALSE 1054.187872 1051.973809 1181.419754 1170.237748 888.042874 945.2413166 1146.900734 738.8448225 848.5740236 996.1434058 1.058269187 1.056046552 1.18599365 1.174768352 0.891480954 0.948900842 1.151340988 0.741705279 0.851859299 1 9.960209639 -4.248012228 24.62097285 1.042193828 0.741705033 0.391455953 0.109564285 1251.187677 2294218.207 0.012770771 0.33213472 5.65E-05 4.248012228 -0.300488794 SLGVLPFTLNSGS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 1 SLGVLPFTLNSGSPEK 16 0 P42695 P42695 NCAPD3 Condensin-2 complex subunit D3 1 0 SLGVLPFTLNS(0.021)GS(0.979)PEK 178.22 1.96E-05 118450000 2663 2039.2 2375.8 2764.6 2526.7 3086 1850.3 1069.6 2285 2689.8 TRUE FALSE FALSE 2452.22074 2215.459362 2463.849238 2753.160818 2496.570753 2445.928814 1902.214438 1395.716116 2034.341217 2783.27035 0.881057329 0.795991436 0.885235327 0.989181959 0.896991826 0.878796705 0.683445803 0.50146624 0.730917576 1 11.44256533 -4.511678782 1.59733532 0.928257128 0.442470841 0.659431559 0.083928048 0.2090158 0.709638322 0.010104002 0.13533144 3.08E-05 4.511678782 -0.485786287 SLHDALCVVK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 SLHDALCVVKR 11 1 P17987;E7EQR6;F5H282;E7ERF2;F5GZ03 P17987 TCP1 T-complex protein 1 subunit alpha 0 1 SLHDALCVVK(1)R 122.7 4.19E-08 0 1057.1 1459.7 915.4 673.57 1648.3 2436.4 1145.6 1020.7 2180.9 1257.7 FALSE TRUE FALSE 973.4294196 1585.869964 949.3255293 670.7829458 1628.645099 1931.063176 1177.742453 1331.906731 1941.660726 1301.404981 0.747983474 1.218582983 0.729462037 0.515429828 1.25145141 1.483829556 0.904977674 1.023437554 1.491972717 1 10.34585427 -5.707187324 24.99999846 0.870876699 1.169993025 0.076594643 0.29692049 94.55468138 43571.25333 0.033388561 0.066777091 1.96E-06 5.707187324 0.299116326 SLHLS(ph)PQEQSASYQDR ddPTM_HeLa_Curcumin_4h_R1 1 SLHLSPQEQSASYQDR 16 0 Q9H410-4;Q9H410;Q5JW53 Q9H410-4 DSN1 Kinetochore-associated protein DSN1 homolog 1 0 S(0.001)LHLS(0.999)PQEQSASYQDR 72.21 0.0074316 0 1289.3 1000 1100.3 868.53 1577.3 2602.2 1137.9 702.76 1468.1 1263.1 TRUE FALSE FALSE 1187.250545 1086.435544 1141.078086 864.936253 1558.491728 2062.474387 1169.826411 917.0282889 1307.053103 1306.992631 0.908383503 0.831248408 0.873056251 0.661775922 1.192425795 1.578030616 0.895052033 0.701632333 1.000046268 1 10.35203529 -5.70525656 24.9999585 0.919861208 1.112464757 0.154847256 0.229963545 138.3741889 61572.00476 0.033948509 0.067896994 1.97E-06 5.70525656 0.192603549 S(ph)PSPGLFR ddPTM_HeLa_Curcumin_4h_R1 1 SPSPGLFR 8 0 Q9HAW4-2;Q9HAW4-3;Q9HAW4;E7ESG2 Q9HAW4-2 CLSPN Claspin 1 0 S(0.845)PS(0.155)PGLFR 93.178 0.019046 62479000 5773.1 4424.8 4881.4 4939.2 4830.2 5065.6 3558.2 1425.2 5923.1 4800 TRUE FALSE FALSE 5316.153043 4807.259995 5062.308978 4918.762899 4772.60302 4014.937459 3658.033516 1859.736919 5273.350749 4966.799643 1.070337728 0.967878783 1.019229553 0.990328431 0.960901056 0.808355027 0.736497096 0.37443365 1.061720047 1 12.27810084 -4.197321484 0.834764985 1.027534163 1.89E-14 0.963535098 0.038533811 0.328483144 0.154666567 0.006324309 0.318104764 6.35E-05 4.197321484 -1.027534163 down SLHPWYGITPTS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 2 SLHPWYGITPTSSPK 15 0 Q8N3F8;H0Y6J8 Q8N3F8 MICALL1 MICAL-like protein 1 1 0 SLHPWYGITPT(0.004)S(0.606)S(0.39)PK;SLHPWYGIT(0.006)PT(0.059)S(0.468)S(0.468)PK ; 183.96 3.31E-05 29871000 6453.4 5741.1 4892.3 4583.7 7902.4 13700.4 5534.9 1177.34 9488.2 5347.9 TRUE FALSE FALSE 5942.60658 6237.335102 5073.612942 4564.733864 7808.169041 10858.7826 5690.194398 1536.305546 8447.368198 5533.739127 1.07388629 1.127146575 0.916850763 0.824891409 1.411011409 1.962286685 1.028272975 0.277625221 1.526520858 1 12.43403892 -5.761293392 24.99999015 1.020429526 1.216296289 0 0.427858344 10.47895382 1793883.045 0.058252376 0.11087982 1.73E-06 5.761293392 0.195866762 SLIEEGGDWDRR ddPTM_HeLa_Curcumin_4h_R1 4 SLIEEGGDWDRR 12 1 Q15008;Q15008-4;C9J0E9;Q15008-3;Q15008-2;H7C531 Q15008 PSMD6 26S proteasome non-ATPase regulatory subunit 6 0 0 ;;; ;;; 181.4 0.00012582 106789000 12402.1 10012.7 10781.1 11639 11256.8 12197 9685 9083.4 11840.5 11453.3 FALSE FALSE TRUE 11420.4607 10878.15317 11180.65705 11590.8409 11122.57001 9667.204711 9956.735034 11852.88685 10541.62677 11851.30132 0.963646134 0.917886811 0.943411761 0.978022631 0.938510439 0.815708288 0.840138544 1.000133785 0.889491077 1 13.53275786 -6.769901711 0.394948763 0.997991676 0.884376751 0 0.061861856 1.069793452 0.39519705 0.025424539 0.046863761 1.70E-07 6.769901711 -0.113614924 DTSGGIDLGEEQHPLGT(ph)PTPGR ddPTM_HeLa_Curcumin_4h_R1 2 DTSGGIDLGEEQHPLGTPTPGR 22 0 Q9UIF8-4;Q9UIF8-2;Q9UIF8-5;Q9UIF8-3;Q9UIF8 Q9UIF8-4 BAZ2B Bromodomain adjacent to zinc finger domain protein 2B 1 0 DTSGGIDLGEEQHPLGT(0.741)PT(0.259)PGR;DTSGGIDLGEEQHPLGT(0.776)PT(0.224)PGR ; 133.58 1.87E-05 43610000 2021.55 1614.8 1629.56 1556.84 2022.36 1851.64 1419.22 463.12 2242.95 1890.21 TRUE FALSE FALSE 1861.542184 1754.376117 1689.952927 1550.398209 1998.244678 1467.588992 1459.039494 604.3231561 1996.903997 1955.894657 0.951759942 0.896968613 0.864030648 0.792679812 1.021652506 0.750341531 0.745970387 0.308975309 1.020967049 1 10.93361295 -4.195306095 1.029582923 0.952816547 1.83E-31 0.831364952 0.083003407 0.582412204 0.438044456 0.012482371 0.627864715 6.38E-05 4.195306095 -0.952816547 down SLIPDIKPLAGQEAVVDLHADDS(ph)RISEDETER ddPTM_HeLa_Curcumin_4h_R1 1 SLIPDIKPLAGQEAVVDLHADDSRISEDETER 32 2 S4R3H4;E7EQT4;Q9UKV3;G3V3B0;Q9UKV3-3;Q9UKV3-2 S4R3H4 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 SLIPDIKPLAGQEAVVDLHADDS(0.489)RIS(0.489)EDET(0.021)ER 75.718 4.88E-06 4224800 1022.6 940.72 1148.3 1176.3 1482.1 1356.1 1177 1195 1128.1 1148.2 TRUE FALSE FALSE 941.660131 1022.031645 1190.857008 1171.432782 1464.426925 1074.829574 1210.023452 1559.349999 1004.350252 1188.099865 0.792576583 0.860223686 1.002320633 0.985971649 1.232578985 0.904662651 1.018452647 1.312473846 0.84534161 1 10.21444039 -6.304938794 1.979239049 0.897560642 1.092771457 0.419259296 0.119922687 0.301895876 2.308284872 0.020716922 0.035628247 4.96E-07 6.304938794 0.195210815 SLIPDIKPLAGQEAVVDLHADDSRIS(ph)EDETER ddPTM_HeLa_Curcumin_4h_R1 1 SLIPDIKPLAGQEAVVDLHADDSRISEDETER 32 2 S4R3H4;E7EQT4;Q9UKV3;G3V3B0;Q9UKV3-3;Q9UKV3-2 S4R3H4 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 SLIPDIKPLAGQEAVVDLHADDS(0.228)RIS(0.694)EDET(0.077)ER 55.669 0.00046711 246150000 1865.5 1738.6 1881.1 1705 1943 2041.1 1717.5 1664.8 1803.3 1797.8 TRUE FALSE FALSE 1717.843707 1888.876837 1950.815221 1697.945162 1919.830994 1617.752852 1765.688428 2172.389856 1605.482502 1860.273416 0.923436142 1.015375923 1.048671235 0.912739572 1.032015497 0.869631764 0.94915533 1.167779874 0.863035771 1 10.86129896 -4.258427458 24.72935581 0.966384207 1.16777996 0.496815931 0.062984034 141.1508588 1158846.49 0.00743659 0.069841727 5.52E-05 4.258427458 0.201395753 SLIPDIKPLAGQEAVVDLHADDSRISEDET(ph)ERNGDDGTHDK ddPTM_HeLa_Curcumin_4h_R1 1 SLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDK 41 3 S4R3H4;E7EQT4;Q9UKV3;G3V3B0;Q9UKV3-3;Q9UKV3-2 S4R3H4 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 SLIPDIKPLAGQEAVVDLHADDS(0.044)RIS(0.044)EDET(0.675)ERNGDDGT(0.236)HDK 49.464 0.0016364 690430000 3832.6 3441.5 3195 3904 3369.8 4408.9 3714.8 3510.4 4408.1 3595.5 TRUE FALSE FALSE 3529.245666 3738.967925 3313.409511 3887.846282 3329.617336 3494.444441 3819.02729 4580.7048 3924.542459 3720.443357 0.948608896 1.004979129 0.890595338 1.044995424 0.894951761 0.939254843 1.026497899 1.231225518 1.054858812 1 11.86125884 -4.290983297 2.954644674 0.968631972 1.266243346 0.677064401 0.053439662 0.125641904 1.630364411 0.006070692 0.085089154 5.12E-05 4.290983297 0.297611374 SLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGT(ph)HDK ddPTM_HeLa_Curcumin_4h_R1 2 SLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDK 41 3 S4R3H4;E7EQT4;Q9UKV3;G3V3B0;Q9UKV3-3;Q9UKV3-2 S4R3H4 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 SLIPDIKPLAGQEAVVDLHADDS(0.054)RIS(0.054)EDET(0.198)ERNGDDGT(0.695)HDK;SLIPDIKPLAGQEAVVDLHADDS(0.008)RIS(0.008)EDET(0.448)ERNGDDGT(0.535)HDK ; 56.637 6.41E-05 839605500 3391.5 2724.9 3207.9 2874.2 2967.6 4191.6 3611.8 2661.8 3771.5 3160.8 TRUE FALSE FALSE 3123.059196 2960.428214 3326.787596 2862.307322 2932.213308 3322.214911 3713.137387 3473.370567 3357.775886 3270.637565 0.954877798 0.905153248 1.017167916 0.875152708 0.896526518 1.015769814 1.135294668 1.061985774 1.02664261 1 11.67535618 -4.957885037 5.388686637 0.962537231 1.096113779 0.552515985 0.05159278 0.105073199 7.338476951 0.007033431 0.021537388 1.10E-05 4.957885037 0.133576548 SLIVGLK ddPTM_HeLa_Curcumin_4h_R1 1 SLIVGLK 7 0 P21980-2;P21980 P21980-2 TGM2 Protein-glutamine gamma-glutamyltransferase 2 0 0 108.24 0.015054 2035900 3286.4 2584.8 2488.7 3023.7 2706.9 3029.1 2352.7 2615.7 2743.5 2844.9 FALSE FALSE TRUE 3026.277972 2808.218594 2580.933411 3011.188731 2674.621985 2400.830515 2418.71043 3413.214889 2442.544914 2943.760063 1.028031466 0.953956346 0.876747206 1.022905626 0.908573365 0.815565964 0.8216398 1.159474555 0.829736412 1 11.52344437 -7.107446819 4.489873187 1.013029094 0.92574117 0 0.111280846 0.314636142 10.45814537 0.015161047 0.01876467 7.81E-08 7.107446819 -0.087287924 SLKES(ph)EQES(ph)EEEILAQKK ddPTM_HeLa_Curcumin_4h_R1 2 SLKESEQESEEEILAQKK 18 2 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 2 0 S(0.025)LKES(0.975)EQES(1)EEEILAQKK;S(0.001)LKES(0.999)EQES(1)EEEILAQKK ; 125.04 0.00018513 379200000 15934.9 12754.9 13541.8 14615 13194.4 14403.1 13292.1 9361.5 15984.3 13745.7 TRUE FALSE FALSE 14673.63585 13857.37672 14043.67102 14554.527 13037.0654 11415.7347 13665.04055 12215.77825 14230.86228 14223.36205 1.031657339 0.974268719 0.987366487 1.02328317 0.916595201 0.802604522 0.960746166 0.858853076 1.000527318 1 13.7959749 -5.651270756 4.438393859 1.010077354 0.879510482 0.684335733 0.039739463 0.084750078 2.904846298 0.005487056 0.011222854 2.23E-06 5.651270756 -0.130566872 SLKESEQES(ph)EEEILAQK ddPTM_HeLa_Curcumin_4h_R1 1 SLKESEQESEEEILAQK 17 1 Q9BW71 Q9BW71 HIRIP3 HIRA-interacting protein 3 1 0 SLKESEQES(1)EEEILAQK 74.657 0.0062956 30519000 3653 2999.2 3299 3348.9 3657.1 4135.1 3732.7 2999.4 4045.7 4003.3 TRUE FALSE FALSE 3363.861195 3258.437484 3421.263842 3335.043139 3613.491471 3277.433648 3837.429516 3913.903252 3601.896832 4142.414377 0.812053283 0.786603461 0.825910576 0.805096457 0.872315307 0.791189232 0.926375096 0.944836247 0.869516302 1 12.01625616 -9.280378895 1.000855618 1.000268964 0.842183392 0.122575369 0.064848123 0.332313961 0.595107518 0.037261635 0.01000663 5.24E-10 9.280378895 -0.158085572 SLLDASEEAIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 SLLDASEEAIKK 12 1 P18206;P18206-2 P18206 VCL Vinculin 0 1 SLLDASEEAIK(1)K 163.9 1.46E-06 1105700 312.98 360.49 678.36 304.04 1201.6 1489.5 971.53 1125.8 805.41 502.82 FALSE TRUE FALSE 288.2073027 391.6491493 703.5006183 302.781963 1187.271705 1180.56091 998.7885171 1469.051237 717.058538 520.2929576 0.553932738 0.752747358 1.352124045 0.58194515 2.281929224 2.269031115 1.919665647 2.823507826 1.378182287 1 9.02318037 -5.755682696 24.99995061 0.815335611 2.290793071 0.792076027 0.344649419 38.30605388 166352.6205 0.044127993 0.086371848 1.76E-06 5.755682696 1.475457461 SLLGDSAPT(ph)LHLNKGTPS(ph)QSPVVGR ddPTM_HeLa_Curcumin_4h_R1 1 SLLGDSAPTLHLNKGTPSQSPVVGR 25 1 C9J2I0;B8ZZY2;P52594-2;P52594-3;P52594;P52594-4 C9J2I0 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 2 0 SLLGDS(0.024)APT(0.601)LHLNKGT(0.497)PS(0.512)QS(0.365)PVVGR 85.745 0.00012947 353900000 2809.5 3008.8 2439 2754.4 3377.3 4597.6 2634 400.09 3772.9 2456.1 TRUE FALSE FALSE 2587.12511 3268.867265 2529.391486 2743.003023 3337.027903 3644.005934 2707.902951 522.0755992 3359.022309 2541.449292 1.017972351 1.286221714 0.995255539 1.079306611 1.313041308 1.43382988 1.065495566 0.205424362 1.321695585 1 11.31143573 -4.262378573 7.287751573 1.082890277 0.194722085 0.723882607 0.171265894 0.043121295 20.0694751 0.023851666 0.189642815 5.47E-05 4.262378573 -0.888168191 SS(ph)MEMEGIFNHK ddPTM_HeLa_Curcumin_4h_R1 1 SSMEMEGIFNHK 12 0 E7EPJ7;O75962-5;O75962-4;O75962;E7EWP2;O75962-2 E7EPJ7 TRIO Triple functional domain protein 1 0 S(0.042)S(0.958)MEMEGIFNHK 63.534 0.019984 62707000 5701.9 4681.2 5417.8 5609.3 5623.2 5209.4 4388.6 1046.1 4993.5 4510.4 TRUE FALSE FALSE 5250.588598 5085.822069 5618.588434 5586.090203 5556.147013 4128.911718 4511.732305 1365.051074 4445.725543 4667.136064 1.125012969 1.089709406 1.203862145 1.196898939 1.190483186 0.884677811 0.966702544 0.292481525 0.95255966 1 12.18832181 -4.194873629 1.863573124 1.084813523 7.00E-18 0.842661726 0.10163891 0.290876011 0.893427528 0.014460172 0.577822117 6.38E-05 4.194873629 -1.084813523 down SLLGDSAPTLHLNKGT(ph)PSQSPVVGR ddPTM_HeLa_Curcumin_4h_R1 2 SLLGDSAPTLHLNKGTPSQSPVVGR 25 1 C9J2I0;B8ZZY2;P52594-2;P52594-3;P52594;P52594-4 C9J2I0 AGFG1 Arf-GAP domain and FG repeat-containing protein 1 1 0 S(0.001)LLGDS(0.01)APT(0.008)LHLNKGT(0.893)PS(0.08)QS(0.008)PVVGR;SLLGDS(0.001)APT(0.009)LHLNKGT(0.877)PS(0.104)QS(0.009)PVVGR ; 60.635 0.0015693 64684000 3535.7 3164.8 2665.2 2929.3 3470.1 5349.2 3511.9 839.45 4209.5 3139 TRUE FALSE FALSE 3255.845614 3438.35121 2763.974657 2917.179333 3428.721324 4239.715622 3610.434462 1095.394441 3747.728382 3248.080016 1.002390827 1.058579589 0.850956455 0.89812422 1.055614796 1.305299008 1.111559581 0.337243675 1.153828835 1 11.66537146 -4.256595385 24.94341089 1.017533501 0.337243387 0.741262821 0.12486173 192.3205089 990290.482 0.016860733 0.185177949 5.54E-05 4.256595385 -0.680290114 VVPGQFDDADS(ph)S(ph)DSENRDLK ddPTM_HeLa_Curcumin_4h_R1 1 VVPGQFDDADSSDSENRDLK 20 1 E9PFQ8;Q9BRS2 E9PFQ8 RIOK1 Serine/threonine-protein kinase RIO1 2 0 VVPGQFDDADS(0.989)S(0.952)DS(0.059)ENRDLK 74.812 0.0032648 7410600 1713.9 1352.9 1461.7 1821.9 1567.6 1810.7 1159.2 629.36 1687 1715.2 TRUE FALSE FALSE 1578.243007 1469.838648 1515.871888 1814.361461 1548.907394 1435.140409 1191.724032 821.2489668 1501.940321 1774.803072 0.889249648 0.828169993 0.85410709 1.022288889 0.872720708 0.80861952 0.671468317 0.462726812 0.846257449 1 10.79344324 -4.194262827 0.888576082 0.935823417 0.144220738 0.818016834 0.065024776 0.701603495 0.378308248 0.010889254 0.553519705 6.39E-05 4.194262827 -0.791602679 down SLLSNLDEVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 SLLSNLDEVKK 11 1 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 1 SLLSNLDEVK(1)K 136.81 0.0001106 878090 227.76 375.32 405.07 178.1 678.35 785.48 516.4 491.08 827.2 392.92 FALSE TRUE FALSE 209.7325557 407.7609884 420.0822505 177.3630694 670.2611193 622.5625938 530.8887942 640.8080313 736.4582296 406.5739408 0.515853415 1.002919635 1.033224731 0.436238164 1.648558976 1.531240769 1.305761981 1.576116832 1.81137588 1 8.667373939 -5.751301827 24.99997678 0.78622194 1.501574283 0.264308716 0.382959799 92.23097542 227446.9707 0.034689176 0.068747832 1.77E-06 5.751301827 0.715352343 SLLVNPEGPTLMR ddPTM_HeLa_Curcumin_4h_R1 1 SLLVNPEGPTLMR 13 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 0 122.7 0.0011723 775760 433.68 528.32 522.8 533.19 529.91 555.57 522.75 418.16 627.5 439.96 FALSE FALSE TRUE 399.3537704 573.9856267 542.1754279 530.9838011 523.5911693 440.3385194 537.4169581 545.655059 558.6648199 455.2485773 0.877221347 1.260818057 1.190943706 1.166360155 1.150121484 0.967248535 1.180491241 1.198587072 1.22716434 1 8.830510698 -7.268461016 24.99245817 0.94202119 1.153802919 0.044466375 0.11806377 284.2591854 1011776.04 0.01447524 0.016742119 5.39E-08 7.268461016 0.211781729 SLMASLTNMSRSS(ph)PSELSLNDSLR ddPTM_HeLa_Curcumin_4h_R1 1 SLMASLTNMSRSSPSELSLNDSLR 24 1 Q9ULS6 Q9ULS6 KCNS2 Potassium voltage-gated channel subfamily S member 2 1 0 S(0.001)LMAS(0.001)LT(0.001)NMS(0.01)RS(0.028)S(0.638)PS(0.197)ELS(0.108)LNDS(0.016)LR 45.511 0.012181 6380400 596.7 626.24 660.32 455.82 652.86 576.85 520.71 273.74 558.95 606.6 TRUE FALSE FALSE 549.4705654 680.3693951 684.7920401 453.9339376 645.0750709 457.2048076 535.3197212 357.2020659 497.6345834 627.6793048 0.875400162 1.083944285 1.090990311 0.723194048 1.027714417 0.728405101 0.852855458 0.569083707 0.792816618 1 9.293883833 -3.618123522 0.638375897 0.955901511 1.81E-17 0.427766684 0.125357631 4.083142378 0.643046912 0.019352669 3.447552777 0.000240922 3.618123522 -0.955901511 SLMS(ph)S(ph)PEDLTKDFEELK ddPTM_HeLa_Curcumin_4h_R1 1 SLMSSPEDLTKDFEELK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 S(0.002)LMS(0.997)S(0.997)PEDLT(0.003)KDFEELK 94.45 0.0057578 11667000 3068.3 2784.7 2746.8 3062.1 3322.8 3409.1 2873.5 3163.3 3302.6 2628.4 TRUE FALSE FALSE 2825.440817 3025.39706 2848.598824 3049.429842 3283.17778 2702.014232 2954.122676 4127.775608 2940.313043 2719.736704 1.038865568 1.11238601 1.047380366 1.121222447 1.207167508 0.993483754 1.086179655 1.517711476 1.081102093 1 11.40925128 -4.264062591 4.315900607 1.046738314 1.551699753 0.801150841 0.064735767 0.066562962 2.90820688 0.009740153 0.102442693 5.44E-05 4.264062591 0.504961439 SLMS(ph)S(ph)PEDLTKDFEELKAEEVDVTK ddPTM_HeLa_Curcumin_4h_R1 2 SLMSSPEDLTKDFEELKAEEVDVTK 25 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 S(0.113)LMS(0.892)S(0.892)PEDLT(0.102)KDFEELKAEEVDVTK;S(0.021)LMS(0.732)S(0.776)PEDLT(0.471)KDFEELKAEEVDVTK ; 53.998 0.0032466 93172600 3223 2562.7 2358.8 2749.4 2452.3 3247.4 2480.7 2630.1 3049.2 2576.4 TRUE FALSE FALSE 2967.896149 2784.208369 2446.219203 2738.023711 2423.057924 2573.852634 2550.301766 3432.005383 2714.710389 2665.929708 1.113268718 1.044366759 0.917585785 1.027042725 0.908897904 0.965461552 0.956627535 1.287357792 1.018297812 1 11.38042303 -6.975021576 24.98464132 1.05482117 1.000370919 0.015472421 0.10448977 550.5714108 550706.8448 0.016682408 0.021924591 1.06E-07 6.975021576 -0.054450251 SLMS(ph)SPEDLTKDFEELKAEEVDVTK ddPTM_HeLa_Curcumin_4h_R1 1 SLMSSPEDLTKDFEELKAEEVDVTK 25 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(0.008)LMS(0.493)S(0.493)PEDLT(0.007)KDFEELKAEEVDVTK 64.589 0.010499 17022000 2196.8 1757.4 1795.5 1744.3 1691.3 2059.7 1448.1 4904 1829.8 1983.7 TRUE FALSE FALSE 2022.920962 1909.301825 1862.042809 1737.082549 1671.132352 1632.495002 1488.729789 6399.207025 1629.075518 2052.633427 0.985524709 0.930171846 0.907148244 0.846270223 0.814140669 0.795317362 0.725277962 3.117559589 0.793651461 1 11.00326029 -4.258094153 24.99970511 0.934791188 3.117560402 0.975546276 0.106429997 37.42927605 279705.1867 0.016108924 0.156037394 5.52E-05 4.258094153 2.182769214 SLMSS(ph)PEDLTKDFEELKAEEVDVTK ddPTM_HeLa_Curcumin_4h_R1 1 SLMSSPEDLTKDFEELKAEEVDVTK 25 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(0.028)LMS(0.194)S(0.543)PEDLT(0.236)KDFEELKAEEVDVTK 46.92 0.012232 51430000 1571.7 724.9 1121.3 1050.3 1010.6 1013.4 658.93 1998.7 1193.1 851.28 TRUE FALSE FALSE 1447.298287 787.5571259 1162.856364 1045.954137 998.549255 803.2094166 677.4178024 2608.094429 1062.219915 880.8619166 1.643047859 0.894075576 1.32013468 1.187421226 1.133604753 0.911844866 0.769039721 2.960843669 1.205886978 1 9.782772071 -4.252459754 24.98401088 1.21117175 2.96084458 0.82418491 0.252035638 459.5150036 1278481.392 0.043068625 0.702686088 5.59E-05 4.252459754 1.749672829 SLMTGS(ph)RS(ph)T(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SLMTGSRSTK 10 1 Q8WXI7 Q8WXI7 MUC16 Mucin-16 3 0 S(0.002)LMT(0.005)GS(0.998)RS(0.998)T(0.998)K 55.112 0.018143 6745900 2139.1 2567.5 1895.8 2965.4 2287.1 820.29 972.86 972.1 2637.7 2365.4 TRUE FALSE FALSE 1969.787978 2789.423259 1966.060016 2953.129961 2259.827826 650.1526074 1000.155833 1268.488815 2348.350909 2447.597474 0.804784283 1.13965768 0.803261172 1.206542331 0.923284098 0.265628893 0.40862758 0.518258753 0.959451435 1 11.2571506 -5.271574208 24.26950802 0.939496444 0.39861733 0.790169715 0.135833496 157.6180767 377442.7349 0.019976066 0.045177966 5.35E-06 5.271574208 -0.540879114 SLNDDGSS(ph)DPR ddPTM_HeLa_Curcumin_4h_R1 1 SLNDDGSSDPR 11 0 P54259 P54259 ATN1 Atrophin-1 1 0 S(0.01)LNDDGS(0.058)S(0.933)DPR 140.45 0.0013477 5705800 1832.7 1504.8 1684.4 1876.9 2118.8 1934 1659 1497 1482.2 1505.9 TRUE FALSE FALSE 1687.639861 1634.868207 1746.825346 1869.133885 2093.534694 1532.866599 1705.547075 1953.428409 1319.606368 1558.229913 1.083049329 1.049182918 1.12103184 1.199523812 1.343533888 0.983722997 1.094541352 1.253620145 0.846862429 1 10.6056924 -7.382431651 0.639361312 1.017030429 1.166458224 0.370799664 0.107507572 0.640834752 0.576256514 0.0294165 0.031992376 4.15E-08 7.382431651 0.149427795 SLNDLIEER ddPTM_HeLa_Curcumin_4h_R1 1 SLNDLIEER 9 0 Q96KB5;Q96KB5-2;E5RFX4 Q96KB5 PBK Lymphokine-activated killer T-cell-originated protein kinase 0 0 148.91 0.015107 3699300 2113 1732.1 1733.2 1844.8 1837.3 2287.4 1841 1621.5 2169.5 2136.5 FALSE FALSE TRUE 1945.75382 1881.815006 1797.433917 1837.166706 1815.391397 1812.967456 1892.653505 2115.887886 1931.511278 2210.743216 0.880135606 0.851213742 0.81304509 0.831017684 0.821167915 0.820071478 0.856116392 0.957093465 0.873693183 1 11.11031575 -8.610795609 0.667763938 0.99829457 0.845832166 0.151005944 0.054345128 0.320625556 0.286291129 0.024425019 0.009729058 2.45E-09 8.610795609 -0.152462403 SLNFQEDDDT(ph)S(ph)RETFASDTNEALASLDESQEGHAEAK ddPTM_HeLa_Curcumin_4h_R1 1 SLNFQEDDDTSRETFASDTNEALASLDESQEGHAEAK 37 1 Q9H814 Q9H814 PHAX Phosphorylated adapter RNA export protein 2 0 S(0.078)LNFQEDDDT(0.482)S(0.469)RET(0.32)FAS(0.319)DT(0.319)NEALAS(0.01)LDES(0.003)QEGHAEAK 64.342 4.05E-05 6176100 824.17 661.88 666.5 565.74 655.55 757.2 638.36 403.29 1006.9 675.43 TRUE FALSE FALSE 758.9360748 719.0899579 691.2010763 563.3991178 647.7329944 600.1481846 656.2706635 526.2512645 896.4455891 698.9011422 1.085899033 1.028886511 0.988982611 0.806121329 0.926787718 0.858702538 0.939003564 0.75296953 1.282650056 1 9.448944594 -6.445442823 4.104686271 1.039981824 0.865699859 0.568529058 0.094047366 0.097859035 3.098520229 0.008648096 0.013262508 3.59E-07 6.445442823 -0.174281965 SLNFQEDDDT(ph)SRETFASDTNEALASLDESQEGHAEAK ddPTM_HeLa_Curcumin_4h_R1 1 SLNFQEDDDTSRETFASDTNEALASLDESQEGHAEAK 37 1 Q9H814 Q9H814 PHAX Phosphorylated adapter RNA export protein 1 0 S(0.003)LNFQEDDDT(0.226)S(0.226)RET(0.226)FAS(0.226)DT(0.079)NEALAS(0.015)LDES(0.001)QEGHAEAK 55.213 0.00019324 12306000 2173.3 1879 1789.4 1799.4 1779.5 2471.5 1965.7 1674.5 2324.8 1950.5 TRUE FALSE FALSE 2001.281012 2041.412387 1855.716738 1791.95456 1758.280625 1958.88304 2020.852252 2185.047342 2069.775256 2018.27973 0.99157762 1.011461572 0.919454678 0.887862338 0.871177864 0.970570636 1.001274611 1.082628592 1.025514564 1 10.97891043 -6.775463505 24.99232597 0.997069548 0.951354161 0.152978378 0.057119463 387.6846394 690889.5499 0.009658234 0.012727493 1.68E-07 6.775463505 -0.045715388 SLNFQEDDDTSRETFASDTNEALASLDES(ph)QEGHAEAK ddPTM_HeLa_Curcumin_4h_R1 1 SLNFQEDDDTSRETFASDTNEALASLDESQEGHAEAK 37 1 Q9H814 Q9H814 PHAX Phosphorylated adapter RNA export protein 1 0 SLNFQEDDDTSRETFAS(0.002)DT(0.006)NEALAS(0.435)LDES(0.556)QEGHAEAK 65.757 1.07E-05 22317000 968.29 826.11 796.53 819.43 778.08 1085.5 885.7 1062.4 1257.3 892.17 TRUE FALSE FALSE 891.6488248 897.5152673 826.0501025 816.0394158 768.8019042 860.3550639 910.5503583 1386.320869 1119.377336 923.1728411 0.965852531 0.972207183 0.894794632 0.883950848 0.832782194 0.931954479 0.986327064 1.501691566 1.212532785 1 9.850456972 -4.261611166 4.80510106 0.955691271 1.531885287 0.736849391 0.096353523 0.044628568 2.942278475 0.008726752 0.085662067 5.48E-05 4.261611166 0.576194015 SLNSENSYVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 SLNSENSYVSPR 12 0 F5H6W4;Q9H992;Q9H992-2 F5H6W4 7-Mar E3 ubiquitin-protein ligase MARCH7 1 0 SLNSENSYVS(1)PR;SLNSENSYVS(1)PR ; 135.91 0.00171 14059200 2021.98 1536.7 1844.66 2044.42 1859.9 2563.9 2041.74 965.68 1751.38 1618.17 TRUE FALSE FALSE 1861.938149 1669.525501 1913.024722 2035.960732 1837.721907 2032.118239 2099.025729 1260.111387 1559.257996 1674.401287 1.11200234 0.997088042 1.142512692 1.215933568 1.097539713 1.213638722 1.253597776 0.752574306 0.931233156 1 10.70942961 -9.233279682 0.52307525 0.979139962 1.114853511 0.112187946 0.137716049 2.931421806 1.125265363 0.20160042 0.033214199 5.84E-10 9.233279682 0.135713549 S(ph)RTGSESSQTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 4 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 S(0.851)RT(0.147)GS(0.002)ESSQTGTSTTSSR;S(0.999)RT(0.001)GSESSQTGTSTTSSR;S(0.774)RT(0.057)GS(0.166)ES(0.003)SQTGTSTTSSR;S(0.902)RT(0.06)GS(0.038)ESSQTGTSTTSSR ;;; 141.79 0.00011846 311909000 1027.504 739.78 810.63 909.13 798.767 899.138 698.65 204.667 902.75 829.92 TRUE FALSE FALSE 946.1759742 803.7232868 840.6726609 905.3682609 789.2422252 712.6466434 718.2522387 267.0690261 803.7205836 858.7596582 1.101793692 0.935911788 0.978938231 1.054274327 0.919049023 0.829855754 0.836383302 0.310993913 0.93590864 1 9.746110609 -4.194219442 0.998822383 1.031054916 3.68E-28 0.858211513 0.078864238 0.517781585 0.36306436 0.011630542 0.588809992 6.39E-05 4.194219442 -1.031054916 down SLPEEDVAEIQHAEEFLIKPESK ddPTM_HeLa_Curcumin_4h_R1 1 SLPEEDVAEIQHAEEFLIKPESK 23 1 O60832;H7C2Q9;H7C0M1;C9IYT0;O60832-2 O60832 DKC1 H/ACA ribonucleoprotein complex subunit 4 0 0 113.05 3.90E-06 4150500 2157.9 2146.2 2255.9 2450.7 2494.1 3263.5 2189.7 1150.5 2902.7 1768 FALSE FALSE TRUE 1987.099938 2331.707965 2339.505638 2440.559653 2464.359486 2586.613313 2251.137089 1501.282154 2584.281072 1829.437868 1.086180609 1.274548868 1.278811201 1.334048942 1.347058312 1.413884209 1.230507539 0.820624838 1.412609369 1 10.8371847 -7.406789592 2.543845009 1.033885633 1.258635988 0 0.194180828 0.258209398 3.159535072 0.028054014 0.031573816 3.92E-08 7.406789592 0.224750355 SLPELDRDKS(ph)DSDTEGLLFSR ddPTM_HeLa_Curcumin_4h_R1 2 SLPELDRDKSDSDTEGLLFSR 21 2 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 SLPELDRDKS(0.684)DS(0.253)DT(0.062)EGLLFSR;SLPELDRDKS(0.83)DS(0.157)DT(0.013)EGLLFSR ; 85.054 0.00024427 175336000 7776.2 5970 6986.8 7165.7 6653 9007.7 6016.7 2784.7 9285.8 6633.1 TRUE FALSE FALSE 7160.705565 6486.020198 7245.736954 7136.050232 6573.66732 7139.401482 6185.512409 3633.742211 8267.170972 6863.599731 1.043287174 0.944988119 1.055675919 1.039694987 0.957757966 1.040183251 0.901205293 0.529422221 1.204494915 1 12.74474971 -4.26461412 2.41940762 1.016042409 0.418303579 0.826673369 0.069411697 0.082623734 0.585142363 0.004828935 0.102179991 5.44E-05 4.26461412 -0.59773883 SLPELDRDKSDS(ph)DTEGLLFSR ddPTM_HeLa_Curcumin_4h_R1 1 SLPELDRDKSDSDTEGLLFSR 21 2 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 SLPELDRDKS(0.014)DS(0.878)DT(0.107)EGLLFSR 94.188 0.00025135 78082000 1757.8 1321.3 1478.1 1726.3 1637.8 1956.9 1325.9 506.55 2304 1335.8 TRUE FALSE FALSE 1618.668275 1435.507284 1532.879686 1719.157028 1618.270305 1551.016881 1363.101186 660.9947631 2051.256964 1382.218951 1.171065029 1.038552744 1.108999183 1.243766067 1.170777107 1.122120978 0.986168787 0.478212777 1.484031863 1 10.43277045 -4.262101108 2.789279025 1.101365668 0.362839958 0.674576354 0.138361712 0.128346535 1.353967802 0.011973915 0.215508116 5.47E-05 4.262101108 -0.73852571 SLPS(ph)S(ph)PLLTHQSISVR ddPTM_HeLa_Curcumin_4h_R1 1 SLPSSPLLTHQSISVR 16 0 J3QQY7;J3KTM5 J3QQY7 TANC2 2 0 S(0.311)LPS(0.809)S(0.88)PLLTHQSISVR 119.62 0.0020653 4907600 1770.2 1241.5 1333 1306.2 1327.5 1971.8 1070.4 725.41 1253.4 1237.4 TRUE FALSE FALSE 1630.086802 1348.809728 1382.402153 1300.79529 1311.67043 1562.826453 1100.432543 946.5841696 1115.905156 1280.399558 1.273107908 1.053428767 1.079664659 1.015929194 1.024422745 1.220577158 0.859444645 0.73928811 0.871528851 1 10.32237837 -4.613434324 4.925753876 1.111619989 0.765996686 0.444483284 0.114411711 0.104215667 4.165073481 0.015861695 0.064389437 2.44E-05 4.613434324 -0.345623303 KDGSS(ph)PPLLEK ddPTM_HeLa_Curcumin_4h_R1 1 KDGSSPPLLEK 11 1 Q6W2J9-4;Q6W2J9-2;Q6W2J9;H7BYY2;Q6W2J9-3 Q6W2J9-4 BCOR BCL-6 corepressor 1 0 KDGS(0.384)S(0.616)PPLLEK 70.47 0.018513 97861000 6766.4 5528.4 5414.6 5981.1 5384.1 6132 4328.4 1459.1 6325.4 4993.9 TRUE FALSE FALSE 6230.8323 6006.250262 5615.269839 5956.351793 5319.898124 4860.154078 4449.843255 1903.972873 5631.519445 5167.437653 1.20578761 1.162326605 1.086664265 1.152670277 1.029504076 0.940534633 0.861131484 0.368455896 1.089808881 1 12.33523336 -4.192201046 1.161072581 1.104091561 3.12E-16 0.92224567 0.064137827 0.464655395 0.458076214 0.012920261 0.643741547 6.42E-05 4.192201046 -1.104091561 down SLPSTSSTSSTK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 SLPSTSSTSSTKR 13 1 A0A590UJA3;S4R3W2;A0A590UJU2;A0A590UK38;A0A590UK73;B1AKN7;B1AKN5;A0A590UK09;B1AKN8;Q12857-2;Q12857-3;Q12857;Q12857-4 A0A590UJA3 NFIA Nuclear factor 1;Nuclear factor 1 A-type 0 1 SLPSTSSTSSTK(1)R 257.09 5.04E-63 27900000 68.277 138.46 204.61 153.9 0 145.02 127.05 0 139.93 73.727 FALSE TRUE FALSE 62.8728034 150.4278654 212.1930266 153.2632026 0 114.9412173 130.6146811 0 124.5800291 76.28900776 0.824139745 1.971815729 2.781436446 2.008981465 0 1.50665503 1.712103551 0 1.633001041 1 6.253403294 -4.245269166 24.42455787 1.200773005 0.000142985 0.173058528 0.768899666 3401.247194 5137357.312 0.112645719 3.842598818 5.69E-05 4.245269166 -1.20063002 (ac)S(ph)DEFSLADALPEHSPAK ddPTM_HeLa_Curcumin_4h_R1 3 SDEFSLADALPEHSPAK 17 0 Q8NDC0 Q8NDC0 MAPK1IP1L MAPK-interacting and spindle-stabilizing protein-like 1 0 S(1)DEFSLADALPEHSPAK;S(0.956)DEFS(0.044)LADALPEHSPAK;S(0.904)DEFS(0.096)LADALPEHSPAK ;; 170.4 9.85E-11 3837290000 11464.4 9785.7 9789.1 9679.7 9819.1 16802 15831.5 25635.1 11903.9 10391.3 TRUE FALSE FALSE 10556.98064 10631.5323 10151.89266 9639.647966 9702.013646 13317.0758 16275.68928 33451.12398 10598.07195 10752.3969 0.981825796 0.988759288 0.944151592 0.896511546 0.902311711 1.238521599 1.513680106 3.111038802 0.985647391 1 13.39237068 -3.991358201 1.402575716 0.976908854 5.324651191 0.988780031 0.068193119 0.162832304 0.173582897 0.010009127 1.191166007 0.00010201 3.991358201 4.347742337 up RLAS(ph)TSDIEEK ddPTM_HeLa_Curcumin_4h_R1 1 RLASTSDIEEK 11 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 RLAS(0.701)T(0.242)S(0.057)DIEEK 135.94 0.00019202 0 1051.8 816.77 868.78 935.32 948.55 1513.1 1749.1 3817.1 1066.4 685.08 TRUE FALSE FALSE 968.5489201 887.3679593 900.9777511 931.4498937 937.2391608 1199.266004 1798.175039 4980.916218 949.418588 708.886479 1.366296225 1.251777239 1.27097607 1.313961997 1.322128703 1.691760302 2.536619179 7.026394727 1.339309771 1 9.469410803 -3.986344159 1.475517174 1.211454607 13.19581087 0.992195265 0.151751312 0.158610743 0.185275266 0.026749383 3.370751552 0.000103194 3.986344159 11.98435626 up SLPTTVPES(ph)PNYR ddPTM_HeLa_Curcumin_4h_R1 6 SLPTTVPESPNYR 13 0 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50;H0YC33 Q6PKG0 LARP1 La-related protein 1 1 0 SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR;SLPTTVPES(1)PNYR ;;;;; 252.2 6.05E-36 2187671100 27440.1 21652.1 21038.9 25514.8 24685.8 29647.7 24973 14316 26062.2 23703.5 TRUE FALSE FALSE 25268.18713 23523.61104 21818.62014 25409.22652 24391.43796 23498.43282 25673.67517 18680.8825 23203.24186 24527.19486 1.030211048 0.959082813 0.889568508 1.035961375 0.994465046 0.95805627 1.04674323 0.761639584 0.946021019 1 14.58209462 -4.254589207 24.83375162 1.000542744 0.761639464 0.646898048 0.048081531 302.2096828 1095561.699 0.006317216 0.082294623 5.56E-05 4.254589207 -0.23890328 SLQTT(ph)SPPVVAPGNENGLAVPVPLRK ddPTM_HeLa_Curcumin_4h_R1 1 SLQTTSPPVVAPGNENGLAVPVPLRK 26 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 0 S(0.002)LQT(0.091)T(0.453)S(0.453)PPVVAPGNENGLAVPVPLRK 135.19 1.61E-08 27152000 3803.1 2624 2543.9 2972.4 3466.4 5436.5 3749 2111.7 3166.9 2713.8 TRUE FALSE FALSE 3502.080622 2850.806868 2638.179172 2960.100996 3425.065444 4308.908618 3854.18685 2755.547609 2819.498993 2808.104348 1.247133364 1.015206885 0.939487585 1.054127849 1.219707325 1.534454594 1.37252266 0.981283908 1.004057771 1 11.45538083 -5.560758077 5.834549665 1.093277228 1.315426692 0.336521028 0.153214753 0.18134296 16.20589779 0.023951157 0.049004548 2.75E-06 5.560758077 0.222149464 SLQTTS(ph)PPVVAPGNENGLAVPVPLRK ddPTM_HeLa_Curcumin_4h_R1 1 SLQTTSPPVVAPGNENGLAVPVPLRK 26 1 O94804 O94804 STK10 Serine/threonine-protein kinase 10 1 0 S(0.006)LQT(0.034)T(0.079)S(0.881)PPVVAPGNENGLAVPVPLRK 75.942 0.00012145 24684000 1407.2 1276.9 1187 1316.5 1601.1 2578.4 1692.9 1106.5 1653.1 1304.5 TRUE FALSE FALSE 1295.818635 1387.269546 1230.991264 1311.052672 1582.007928 2043.610775 1740.398218 1443.866756 1471.759066 1349.831278 0.959985634 1.027735517 0.911959357 0.971271516 1.172004201 1.513974975 1.289345007 1.069664617 1.090328169 1 10.39856337 -5.615458408 4.098619338 0.978488816 1.298206124 0.597840851 0.109872302 0.094484133 2.965619188 0.014648841 0.030439126 2.42E-06 5.615458408 0.319717308 SLRS(ph)LEEQDQETLR ddPTM_HeLa_Curcumin_4h_R1 2 SLRSLEEQDQETLR 14 1 P48681 P48681 NES Nestin 1 0 S(0.075)LRS(0.925)LEEQDQETLR;S(0.009)LRS(0.991)LEEQDQETLR ; 125.39 0.00058606 13930800 1201.18 1036.4 1072.27 1254.42 1039.99 1227.38 1204.73 1347.5 1146.54 1014.71 TRUE FALSE FALSE 1106.105336 1125.981798 1112.009269 1249.229542 1027.588798 972.8075526 1238.531481 1758.346547 1020.767431 1049.971097 1.053462651 1.072393136 1.0590856 1.189775172 0.978682938 0.926508887 1.179586262 1.674661857 0.972186219 1 10.0361339 -4.298048239 3.075582025 1.034798931 1.748424696 0.885341843 0.069333186 0.072690681 1.062961881 0.009379584 0.119638475 5.03E-05 4.298048239 0.713625765 SLRVDIAEGR ddPTM_HeLa_Curcumin_4h_R1 1 SLRVDIAEGR 10 1 Q15056;Q15056-2 Q15056 EIF4H Eukaryotic translation initiation factor 4H 0 0 97.456 0.0064668 1125300 1195.9 638.43 607.2 597.87 714.79 1192.7 669.89 681.26 1218.6 775.04 FALSE FALSE TRUE 1101.243253 693.6130444 629.7033661 595.3961724 706.2665961 945.3205755 688.6853105 888.9730379 1084.922629 801.9725823 1.373168207 0.864883738 0.785193135 0.742414623 0.880661773 1.178744257 0.858739221 1.10848308 1.352817606 1 9.647409105 -7.238684519 24.5835007 1.176218328 0.911658156 0.443557889 0.161768461 585.3474903 632388.1559 0.031040365 0.038001871 5.77E-08 7.238684519 -0.264560172 SES(ph)TENQSYAK ddPTM_HeLa_Curcumin_4h_R1 2 SESTENQSYAK 11 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8 Q96RT1-7 ERBB2IP Protein LAP2 1 0 S(0.01)ES(0.491)T(0.491)ENQS(0.008)YAK;S(0.001)ES(0.984)T(0.015)ENQS(0.001)YAK ; 194.06 2.59E-05 24658000 2845.8 2541 2876.4 3497 2452.7 4787.5 5076.9 10925.1 3071.4 2413.7 TRUE FALSE FALSE 2620.551927 2760.632718 2983.001914 3482.530341 2423.453154 3794.518534 5219.34415 14256.1127 2734.475104 2497.575895 1.049238156 1.105324856 1.194358866 1.39436417 0.970322127 1.519280572 2.089763983 5.707979775 1.094851656 1 11.2863128 -3.96109463 1.457099689 1.070018904 11.05781404 0.986348044 0.160042065 0.189133642 0.204607383 0.023581415 3.373669651 0.000109372 3.96109463 9.987795132 up SLS(ph)ASPALGSTK ddPTM_HeLa_Curcumin_4h_R1 2 SLSASPALGSTK 12 0 O95544;O95544-2 O95544 NADK NAD kinase 1 0 S(0.191)LS(0.762)AS(0.047)PALGSTK;S(0.016)LS(0.84)AS(0.145)PALGSTK ; 139.78 0.0012261 127504000 4619.5 3724.3 4106.4 3562.3 3849.7 4511.6 3971.8 3977.7 4347.6 3876.8 TRUE FALSE FALSE 4253.861701 4046.211897 4258.586796 3547.560146 3803.794842 3575.843304 4083.238018 5190.482419 3870.679157 4011.518511 1.060411834 1.008648442 1.061589716 0.884343457 0.948218195 0.891393943 1.017878394 1.29389467 0.964891262 1 11.96993274 -4.264228664 5.936550124 1.004999332 1.301627595 0.682242108 0.062153895 0.065303116 10.76856732 0.009381602 0.078154311 5.44E-05 4.264228664 0.296628264 SLS(ph)DSES(ph)DDSK ddPTM_HeLa_Curcumin_4h_R1 1 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 2 0 S(0.001)LS(0.999)DS(0.089)ES(0.79)DDS(0.121)K 167.73 0.00060837 12852000 5671.4 5354.5 6169 5394.8 6497.3 5946.5 4846.3 2676.5 5420.1 5214 TRUE FALSE FALSE 5222.502706 5817.319121 6397.628567 5372.477747 6419.823941 4713.128869 4982.274135 3492.552529 4825.52859 5395.186112 0.967993058 1.07824253 1.185803128 0.995790995 1.18991705 0.873580405 0.923466593 0.64734607 0.89441374 1 12.39745701 -4.10611718 1.351272644 1.017300858 0.391292864 0.580783906 0.098018605 0.990646392 1.203796169 0.01358954 0.931888091 7.83E-05 4.10611718 -0.626007994 SLS(ph)DSESDDS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 2 0 S(0.138)LS(0.862)DS(0.004)ES(0.019)DDS(0.977)K 139.19 0.0035059 16733000 7043.4 5950.5 7432.5 6699.3 8088.3 6548.2 5240.9 3068.2 6199 6059.6 TRUE FALSE FALSE 6485.907458 6464.834705 7707.954988 6671.580072 7991.852305 5190.029507 5387.945549 4003.680056 5518.985209 6270.170649 1.034406848 1.031046054 1.229305456 1.064018899 1.274582903 0.827733374 0.859298072 0.638528085 0.88019697 1 12.61428899 -5.068884098 8.557547221 1.052863959 0.772034598 0.572866209 0.118024469 0.185933549 21.75692939 0.015148938 0.038875452 8.53E-06 5.068884098 -0.280829362 SLS(ph)DSESDDSK ddPTM_HeLa_Curcumin_4h_R1 7 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 0 S(0.001)LS(0.981)DS(0.016)ES(0.002)DDSK;S(0.001)LS(0.965)DS(0.033)ES(0.001)DDSK;S(0.041)LS(0.881)DS(0.076)ES(0.002)DDSK;S(0.329)LS(0.411)DS(0.239)ES(0.02)DDSK;S(0.016)LS(0.97)DS(0.011)ES(0.002)DDS(0.001)K;S(0.022)LS(0.656)DS(0.315)ES(0.007)DDSK;S(0.303)LS(0.666)DS(0.027)ES(0.004)DDSK ;;;;;; 224.25 5.83E-12 6414199100 18639.1 23215.9 18393.36 18663.2 20042.37 21187.9 16162.71 10193.08 20401 18937 TRUE FALSE FALSE 17163.79557 25222.57895 19075.0341 18585.97662 19803.37783 16793.2907 16616.19214 13300.90317 18163.06134 19595.05934 0.875924654 1.287190741 0.97346141 0.948503207 1.010631174 0.857016578 0.847978659 0.678788614 0.926920456 1 14.25820232 -4.350890355 1.115691098 0.973568928 0.575270164 0.457329307 0.108811793 1.163034994 1.285217797 0.01728822 0.521043226 4.46E-05 4.350890355 -0.398298764 SLS(ph)DSESDDSKSK ddPTM_HeLa_Curcumin_4h_R1 1 SLSDSESDDSKSK 13 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 0 S(0.005)LS(0.943)DS(0.044)ES(0.005)DDS(0.001)KSK 84.62 0.0077128 189740000 3038.7 3291.8 2670.9 2722.5 2264 3451.6 2517.1 1762.7 3677.6 3158.9 TRUE FALSE FALSE 2798.183689 3576.328524 2769.885904 2711.235016 2237.003279 2735.699252 2587.723052 2300.139116 3274.176481 3268.67154 0.856061447 1.094122943 0.847404173 0.829460832 0.684376895 0.836945291 0.791674238 0.703692337 1.001684152 1 11.6744887 -6.337250115 2.68820998 0.942508827 0.765714818 0.619945312 0.076965458 0.174432203 2.467764771 0.01278641 0.020839937 4.60E-07 6.337250115 -0.176794009 SLS(ph)ELCLAVPAPGIR ddPTM_HeLa_Curcumin_4h_R1 1 SLSELCLAVPAPGIR 15 0 A0A5F9ZHW8;O94827-5;O94827-3;O94827;O94827-7;O94827-2;O94827-6 A0A5F9ZHW8 PLEKHG5 Pleckstrin homology domain-containing family G member 5 1 0 SLS(1)ELCLAVPAPGIR 161.21 0.00029711 8533300 748.68 633.02 627.77 760.41 639.58 577.17 673.02 256.29 821.95 695.45 TRUE FALSE FALSE 689.421188 687.7354281 651.0357084 757.2636249 631.9534262 457.458436 691.9031299 334.4316412 731.7841414 719.6168357 0.95803927 0.95569669 0.904697717 1.052315048 0.878180436 0.635697239 0.961488247 0.46473571 1.016908034 1 9.491085129 -3.692094425 0.552661031 0.980750878 1.77E-15 0.604360957 0.111451929 3.166042789 0.42000816 0.019060711 2.297401875 0.000203192 3.692094425 -0.980750878 ASGQAFELILS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 8 ASGQAFELILSPR 13 0 P16949;P16949-2;A2A2D0 P16949 STMN1 Stathmin 1 0 ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR;ASGQAFELILS(1)PR ;;;;;;; 172.09 0.00017567 2059489100 16321 13364.95 14012.081 15062.34 13327.84 22636.13 19394.68 34134.87 18397.83 13333.77 TRUE FALSE FALSE 15029.17563 14520.15672 14531.38105 15000.01603 13168.91421 17941.14148 19938.84252 44542.43473 16379.63408 13797.11752 1.089298226 1.052405092 1.053218618 1.08718477 0.954468511 1.300354328 1.445145517 3.228386993 1.187177978 1 13.75207927 -3.956293854 1.529442724 1.046693271 5.803316505 0.9794443 0.092449674 0.19223397 0.225993533 0.011235004 1.719743828 0.000110588 3.956293854 4.756623234 up S(ph)IGSPESTPK ddPTM_HeLa_Curcumin_4h_R1 1 SIGSPESTPK 10 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 S(0.746)IGS(0.244)PES(0.002)T(0.008)PK 144.17 0.0012262 63614000 7176.6 5387.9 5697.1 5410.7 6319.3 7160.3 4986.5 1465.5 6457.7 5966.1 TRUE FALSE FALSE 6608.564537 5853.606068 5908.239538 5388.311957 6243.946475 5675.173067 5126.40777 1912.324204 5749.306466 6173.421531 1.070486521 0.94819478 0.957044567 0.87282424 1.011423964 0.919291359 0.830399762 0.309767314 0.931299837 1 12.59185459 -4.192187328 1.624951852 1.006524074 2.81E-19 0.907607278 0.061557977 0.254005391 0.553456705 0.009611177 0.42199968 6.42E-05 4.192187328 -1.006524074 down SLS(ph)FEMQQDELIEKPMSPMQYAR ddPTM_HeLa_Curcumin_4h_R1 2 SLSFEMQQDELIEKPMSPMQYAR 23 1 Q9Y6Y0 Q9Y6Y0 IVNS1ABP Influenza virus NS1A-binding protein 1 0 S(0.029)LS(0.971)FEMQQDELIEKPMSPMQYAR;S(0.025)LS(0.974)FEMQQDELIEKPMSPMQYAR ; 125.83 2.43E-06 134604000 1304.19 880.21 1168.44 1247.19 1041.41 2510 1930.31 1861.67 883.74 1246.78 TRUE FALSE FALSE 1200.961985 956.2914303 1211.743414 1242.029458 1028.991866 1989.397706 1984.469303 2429.284613 786.795933 1290.105512 0.930902142 0.741250558 0.939259156 0.962734789 0.797602875 1.542042637 1.538222482 1.883012351 0.609869445 1 10.33327335 -5.152467659 4.036358131 0.937112048 1.677124298 0.846058364 0.154165252 0.052688262 1.49075735 0.016398406 0.044597138 7.04E-06 5.152467659 0.74001225 SLS(ph)FSDEMSSCR ddPTM_HeLa_Curcumin_4h_R1 1 SLSFSDEMSSCR 12 0 Q14153-2;Q14153 Q14153-2 FAM53B Protein FAM53B 1 0 S(0.006)LS(0.993)FS(0.001)DEMSSCR 122.46 0.0033139 6878300 530.6 495.92 589.59 560.1 638.38 563.08 448.76 476.16 609.13 585.66 TRUE FALSE FALSE 488.6024501 538.785115 611.4407241 557.7824546 630.7677354 446.2908608 461.3509978 621.338992 542.309963 606.0116414 0.806259182 0.889067269 1.00895871 0.920415412 1.040850856 0.736439418 0.761290652 1.025292172 0.894883738 1 9.243201698 -9.633008088 1.470236651 0.999703359 0.883875128 0 0.106939858 0.654858853 2.553904207 0.073348884 0.016886738 2.33E-10 9.633008088 -0.115828232 SLS(ph)GSPLK ddPTM_HeLa_Curcumin_4h_R1 1 SLSGSPLK 8 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 0 S(0.088)LS(0.544)GS(0.367)PLK 98.048 0.016195 176010000 4753.2 3198.6 4337.5 5141.5 5028.3 5823 5266.9 1255.6 5040 3881.6 TRUE FALSE FALSE 4376.979204 3475.072731 4498.251566 5120.225835 4968.340807 4615.244161 5414.675039 1638.42666 4487.124609 4016.485311 1.089753569 0.8652024 1.119947222 1.27480258 1.236987172 1.149075324 1.348112745 0.40792547 1.1171769 1 11.97171789 -8.995916737 0.517275723 0.991701539 1.090128407 0 0.255613696 6.192788955 2.653864856 0.298227428 0.065331581 1.01E-09 8.995916737 0.098426868 SLS(ph)LESTDR ddPTM_HeLa_Curcumin_4h_R1 1 SLSLESTDR 9 0 H0Y7V8;A0A0A0MRJ1;H0Y5V1;A0A0A0MRJ0;Q5VT25-3;Q5VT25-4;Q5VT25-5;Q5VT25;Q5VT25-2;Q5VT25-6 H0Y7V8 CDC42BPA Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase MRCK alpha 1 0 SLS(0.989)LES(0.007)T(0.004)DR 136.49 0.0028992 24589000 4038.6 3156.6 3357 3437.3 3762.1 2882.9 2079.9 1369.9 3728.2 2425 TRUE FALSE FALSE 3718.940548 3429.442438 3481.413373 3423.077363 3717.239415 2284.954043 2138.256396 1787.576204 3319.225787 2509.268569 1.482081509 1.366709997 1.387421584 1.364173371 1.481403569 0.910605613 0.852143299 0.712389349 1.322786181 1 11.29305118 -5.102223818 4.977955948 1.28017551 0.802976193 0.731785001 0.14133661 0.136812282 5.250922556 0.029292882 0.078037535 7.90E-06 5.102223818 -0.477199317 SLS(ph)MDSQVPVYSPSIDLK ddPTM_HeLa_Curcumin_4h_R1 2 SLSMDSQVPVYSPSIDLK 18 0 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 0 S(0.04)LS(0.94)MDS(0.02)QVPVYSPSIDLK;S(0.027)LS(0.965)MDS(0.008)QVPVYSPSIDLK ; 176.68 1.03E-06 32975000 4945.3 4308.2 5118.6 4502.4 4738.2 6803 4792.8 4109.8 4905.9 4863.7 TRUE FALSE FALSE 4553.874287 4680.581611 5308.299819 4483.770262 4681.70006 5391.981114 4927.273069 5362.859101 4367.735044 5032.713213 0.904854716 0.930031459 1.054759052 0.890925048 0.930253694 1.071386524 0.979049046 1.06559998 0.867868853 1 12.29712067 -5.268304582 24.9797111 0.953480927 1.03271557 0.369763442 0.057074306 481.1287919 1750636.184 0.007769972 0.017768066 5.39E-06 5.268304582 0.079234644 SLS(ph)MVDLQDAR ddPTM_HeLa_Curcumin_4h_R1 1 SLSMVDLQDAR 11 0 H0Y3A3;A0A3B3ITG3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-2;Q5VWQ8-5;Q5VWQ8 H0Y3A3 DAB2IP Disabled homolog 2-interacting protein 1 0 S(0.026)LS(0.974)MVDLQDAR 193.11 2.96E-05 11947000 1982.3 1895.1 1913 2388.4 1866.1 2541.2 2074.8 1523.9 2484.6 2261 TRUE FALSE FALSE 1825.398863 2058.904 1983.897463 2378.517434 1843.847976 2014.126475 2133.013304 1988.530095 2212.045596 2339.569582 0.780228499 0.880035377 0.847975405 1.016647443 0.788114186 0.860896162 0.911711847 0.849955526 0.945492544 1 11.19202742 -9.568264575 1.357834655 0.999699411 0.858624825 0.282673559 0.064724464 0.354886051 1.176802447 0.045398328 0.010753218 2.70E-10 9.568264575 -0.141074586 SLS(ph)NPDIASETLTLLSFLR ddPTM_HeLa_Curcumin_4h_R1 1 SLSNPDIASETLTLLSFLR 19 0 Q96PE2 Q96PE2 ARHGEF17 Rho guanine nucleotide exchange factor 17 1 0 S(0.006)LS(0.968)NPDIAS(0.023)ET(0.002)LTLLSFLR 203.23 2.32E-13 32618000 1300.2 1189.4 1432.1 1186.7 1465.6 3034.3 1833.4 555.7 1553.5 1262.4 TRUE FALSE FALSE 1197.287798 1292.206436 1485.174886 1181.78975 1448.123677 2404.951976 1884.84027 725.1303719 1383.084937 1306.268306 0.916571115 0.989235083 1.136960056 0.904706747 1.108595891 1.84108576 1.442919698 0.55511595 1.058806166 1 10.35123554 -5.514419115 24.80786455 0.974609651 1.325830457 0.13663063 0.302615091 399.6805056 1172061.054 0.041284351 0.085961418 3.06E-06 5.514419115 0.351220806 SLS(ph)NSNPDISGTPTSPDDEVR ddPTM_HeLa_Curcumin_4h_R1 1 SLSNSNPDISGTPTSPDDEVR 21 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 S(0.047)LS(0.785)NS(0.168)NPDISGTPTSPDDEVR 117.03 1.28E-05 7994500 490.54 517.12 555.01 479.42 470 613.52 280.04 269.32 502.05 394.4 TRUE FALSE FALSE 451.7132414 561.8175486 575.5791588 477.4362871 464.395557 486.2690362 287.8971687 351.4344282 446.9763711 408.1053706 1.10685444 1.37664826 1.410368989 1.169884842 1.137930521 1.191528147 0.705448125 0.861136494 1.095247461 1 8.672797886 -4.762373387 24.99939638 1.122808844 0.783292247 0.554919663 0.135095585 17.03945691 456142.3135 0.022845066 0.074905916 1.73E-05 4.762373387 -0.339516597 SLS(ph)PDEER ddPTM_HeLa_Curcumin_4h_R1 1 SLSPDEER 8 0 Q5UIP0-2;Q5UIP0;H7C2B5 Q5UIP0-2 RIF1 Telomere-associated protein RIF1 1 0 SLS(1)PDEER 112.3 0.010625 37762000 3667.3 3033.2 3801.1 4005.5 3691.4 4651.7 3753.2 3870.6 3973.5 3860.2 TRUE FALSE FALSE 3377.029335 3295.376292 3941.97211 3988.926302 3647.382466 3686.884985 3858.504691 5050.728122 3537.616991 3994.341663 0.845453299 0.825011121 0.986889065 0.998644242 0.913137326 0.923026946 0.965992651 1.264470731 0.885657084 1 11.96374203 -4.255759527 3.379035198 0.926686175 1.310840445 0.758971013 0.057459851 0.147335655 2.754601378 0.009898559 0.146698449 5.55E-05 4.255759527 0.38415427 SLS(ph)PEDAESLSVLSVPSPDTANQEPTPK ddPTM_HeLa_Curcumin_4h_R1 1 SLSPEDAESLSVLSVPSPDTANQEPTPK 28 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 S(0.194)LS(0.806)PEDAESLSVLSVPSPDTANQEPTPK 117.99 6.92E-11 3678400 2497.1 1402.2 1772.6 1813.4 1586.7 2614.8 1877.3 1337.5 2182.6 1815.6 TRUE FALSE FALSE 2299.4519 1523.39992 1838.294115 1805.896631 1567.779639 2072.461005 1929.971986 1745.297593 1943.174241 1878.691965 1.223964302 0.810883289 0.978496821 0.961252119 0.834505958 1.1031404 1.027295598 0.928996145 1.034322963 1 10.87551282 -7.26756167 24.99811003 1.105760918 0.95532315 0.287414821 0.096961714 475.5319937 1941656.567 0.019102082 0.022128542 5.40E-08 7.26756167 -0.150437768 SLS(ph)PGAASSSSGDGDGKEGLEEPK ddPTM_HeLa_Curcumin_4h_R1 2 SLSPGAASSSSGDGDGKEGLEEPK 24 1 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 0 S(0.045)LS(0.954)PGAAS(0.001)SSSGDGDGKEGLEEPK;S(0.042)LS(0.757)PGAAS(0.054)S(0.054)S(0.016)S(0.076)GDGDGKEGLEEPK ; 114.05 4.67E-07 39495000 13090 11487.5 11183 12013.4 12823.9 9238.1 8069.7 6226.9 12393.5 10595.9 TRUE FALSE FALSE 12053.91269 12480.42831 11597.45182 11963.69173 12670.98337 7322.013925 8296.114064 8125.453145 11033.96406 10964.10674 1.099397605 1.138298688 1.057765315 1.09116885 1.155678586 0.667816732 0.756661191 0.741095772 1.006371456 1 13.42050066 -5.258091616 24.9999568 1.065483156 0.725338211 0.905823897 0.052561624 70.82974817 528928.9957 0.008432962 0.020562015 5.52E-06 5.258091616 -0.340144945 SLS(ph)PGVSR ddPTM_HeLa_Curcumin_4h_R1 3 SLSPGVSR 8 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 S(0.036)LS(0.954)PGVS(0.01)R;S(0.001)LS(0.994)PGVS(0.005)R;S(0.135)LS(0.865)PGVSR ;; 122.94 0.0073567 114198000 16879.6 14297.6 14561.6 16077.3 15885.3 17755.7 16123.3 21663.8 16531.2 14609.9 TRUE FALSE FALSE 15543.56185 15533.42084 15101.26571 16010.77639 15695.87817 14072.96767 16575.6764 28268.99289 14717.76872 15117.59294 1.028177033 1.027506224 0.998919985 1.059082386 1.038252468 0.930900027 1.096449446 1.869940076 0.973552389 1 13.88394083 -4.264262379 4.047798069 1.014007613 1.942511371 0.981932259 0.034882785 0.017532637 0.607442715 0.004216278 0.047269358 5.44E-05 4.264262379 0.928503758 SLS(ph)PILPGR ddPTM_HeLa_Curcumin_4h_R1 2 SLSPILPGR 9 0 A0A3B3IPE9;A0A087WZG4;Q6ZSZ5-1;M0QZS0;A0A590UK10;Q6ZSZ5-2;Q6ZSZ5-6;Q6ZSZ5-5;Q6ZSZ5 A0A3B3IPE9 ARHGEF18 Rho guanine nucleotide exchange factor 18 1 0 S(0.005)LS(0.995)PILPGR;S(0.033)LS(0.967)PILPGR ; 92.239 0.01768 145099000 6099.1 6153.4 6692.7 6969.5 4906.4 5262.9 5725 3520 6855.3 8479.5 TRUE FALSE FALSE 5616.349799 6685.272477 6940.737349 6940.662056 4847.894384 4171.315215 5885.628092 4593.231796 6103.290741 8774.161994 0.640100992 0.761927177 0.791042763 0.791034182 0.552519362 0.475408958 0.670790908 0.523495212 0.695598138 1 13.09904563 -13.52287875 0.156563291 2.346391939 0.529567557 0.223043757 0.129922148 29.32788834 0.308701177 12.15293844 0.209583584 3.00E-14 13.52287875 -1.816824382 SLS(ph)PNHNTLQTLK ddPTM_HeLa_Curcumin_4h_R1 1 SLSPNHNTLQTLK 13 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 0 S(0.007)LS(0.993)PNHNTLQTLK 136.93 0.0011884 25160000 2123.4 1701.8 2323 2178.2 3287.2 4480.3 3184.4 1663.3 3396.3 2107.6 TRUE FALSE FALSE 1955.330649 1848.896009 2409.092424 2169.187186 3248.002287 3551.035277 3273.745694 2170.432513 3023.734387 2180.838943 0.896595622 0.847791174 1.104663153 0.994657213 1.489336155 1.62828864 1.501140515 0.995228245 1.386500547 1 11.09066751 -5.790640899 7.322033772 0.956263392 1.426711164 0.375334119 0.214924916 0.084313862 15.61748445 0.024137121 0.044580195 1.62E-06 5.790640899 0.470447772 SLS(ph)PPQSQSK ddPTM_HeLa_Curcumin_4h_R1 1 SLSPPQSQSK 10 0 B4DWA1;I3L4C2;Q9UQB8-3;Q9UQB8-5;Q9UQB8-4;Q9UQB8-2;Q9UQB8;I3L0Y9;I3L3C6;Q9UQB8-6 B4DWA1 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 0 SLS(1)PPQSQSK 112.64 0.0064681 4812700 2965.3 1830.9 2301.4 2303.3 3350.9 4550 2356.7 1734 3831.6 2455.1 TRUE FALSE FALSE 2730.593376 1989.154838 2386.691909 2293.769555 3310.942706 3606.278711 2422.822659 2262.688618 3411.283066 2540.414542 1.074861339 0.783004035 0.939489154 0.90291152 1.303308043 1.419563087 0.953711538 0.890676927 1.342805676 1 11.31084822 -5.775988597 24.99968074 0.998879412 1.148218146 0.100258084 0.196275406 349.5279593 600587.8727 0.025621076 0.046586342 1.67E-06 5.775988597 0.149338734 SLS(ph)PQEDALTGSR ddPTM_HeLa_Curcumin_4h_R1 2 SLSPQEDALTGSR 13 0 Q96EN8 Q96EN8 MOCOS Molybdenum cofactor sulfurase 1 0 SLS(0.98)PQEDALT(0.013)GS(0.007)R;S(0.16)LS(0.839)PQEDALTGS(0.001)R ; 97.203 0.0084761 146371000 5030 3889.9 4752.2 4779.5 4959.8 4903.6 4240.3 4095.27 5428.9 4684.9 TRUE FALSE FALSE 4631.870192 4226.125623 4928.320712 4759.723695 4900.657624 3886.538085 4359.271406 5343.898971 4833.363252 4847.699926 0.95547791 0.871779542 1.01663073 0.981851964 1.010924294 0.801728272 0.899245306 1.102357624 0.997042582 1 12.24308468 -8.858449737 0.893294157 0.998005382 0.950890888 0.042537965 0.079447241 1.452856635 2.2533945 0.039546452 0.0155957 1.39E-09 8.858449737 -0.047114494 SLS(ph)PSHLTEDR ddPTM_HeLa_Curcumin_4h_R1 3 SLSPSHLTEDR 11 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 0 S(0.215)LS(0.778)PS(0.007)HLTEDR;SLS(0.982)PS(0.018)HLTEDR;S(0.002)LS(0.719)PS(0.128)HLT(0.152)EDR ;; 117.09 0.0021747 177110000 5651.9 4687.43 4271.89 4621.4 5675.4 7924 4711.5 4899.48 6580.4 4775.2 TRUE FALSE FALSE 5204.546151 5092.590562 4430.210001 4602.277871 5607.724562 6280.473078 4843.69201 6393.308898 5858.546583 4941.137845 1.053309241 1.030651385 0.896597128 0.93142066 1.134905509 1.271058059 0.980278665 1.293894058 1.185667506 1 12.27062759 -5.619264209 6.648954859 1.009877447 1.16814838 0.335081512 0.106814241 0.15773203 9.266506777 0.012652813 0.025451466 2.40E-06 5.619264209 0.158270933 GSGS(ph)QSSVPSVDQFTGVGIR ddPTM_HeLa_Curcumin_4h_R1 1 GSGSQSSVPSVDQFTGVGIR 20 0 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 1 0 GSGS(0.93)QS(0.054)S(0.016)VPSVDQFTGVGIR 216.9 1.09E-18 16322000 1110 1169.6 1179.4 1092.1 1154.1 1565.8 1717.1 1850.6 1035.1 955.22 TRUE FALSE FALSE 1022.142329 1270.695012 1223.109602 1087.58118 1140.338111 1241.03543 1765.277205 2414.839421 921.5521197 988.4138239 1.03412387 1.285590085 1.237446879 1.100329794 1.153705142 1.255582834 1.785969765 2.443146142 0.932354544 1 9.948971378 -3.951170592 0.900852093 1.054484828 4.02712765 0.942059199 0.104949023 0.554066502 0.231083406 0.017424562 1.842412629 0.0001119 3.951170592 2.972642821 up SLS(ph)SPPSSK ddPTM_HeLa_Curcumin_4h_R1 3 SLSSPPSSK 9 0 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 0 S(0.021)LS(0.488)S(0.488)PPS(0.003)SK;S(0.042)LS(0.853)S(0.104)PPS(0.001)S(0.001)K;S(0.027)LS(0.486)S(0.486)PPS(0.001)SK ;; 136.02 0.0029724 199439000 22500.3 16464.3 19978.8 21650.9 19211.4 20465.2 18184.9 36917 20522.2 18830.6 TRUE FALSE FALSE 20719.37751 17887.40073 20719.2319 21561.31431 18982.3166 16220.48683 18695.11935 48172.82336 18270.966 19484.96195 1.063352218 0.918010555 1.063344745 1.106561787 0.974203422 0.832461817 0.959463991 2.472307797 0.93769575 1 14.25007349 -4.260239183 24.99584465 1.009951008 2.472308267 0.968741245 0.080086451 12.27431095 255599.3239 0.01121559 0.092769676 5.49E-05 4.260239183 1.462357259 SLS(ph)SPTDNLELSLR ddPTM_HeLa_Curcumin_4h_R1 1 SLSSPTDNLELSLR 14 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 0 S(0.34)LS(0.604)S(0.056)PTDNLELSLR 212.03 5.09E-10 70785000 2000.8 1731.5 1659 1542 1703 1614.3 1328 2953.6 2153.8 1587.5 TRUE FALSE FALSE 1842.434569 1881.163145 1720.483999 1535.619613 1682.692837 1279.475983 1365.260106 3854.139043 1917.533529 1642.665507 1.121612745 1.145189411 1.047373304 0.934834028 1.024367304 0.778902325 0.83112484 2.346271366 1.167330489 1 10.68182302 -4.256352915 24.99998235 1.023417819 2.346271914 0.914526104 0.122847953 113.1689408 556207.5113 0.017574597 0.196704196 5.54E-05 4.256352915 1.322854095 SLS(ph)TSGESLYHVLGLDK ddPTM_HeLa_Curcumin_4h_R1 1 SLSTSGESLYHVLGLDK 17 0 Q9H3Z4-2;Q9H3Z4 Q9H3Z4-2 DNAJC5 DnaJ homolog subfamily C member 5 1 0 S(0.397)LS(0.563)T(0.026)S(0.013)GES(0.002)LYHVLGLDK 116.04 0.00038263 34591000 3181.3 2872 3100.2 2892.1 5764.7 10989 2948.5 765.33 5423.4 2848.6 TRUE FALSE FALSE 2929.496748 3120.242883 3215.096139 2880.133257 5695.959718 8709.757528 3031.226975 998.6755939 4828.466589 2947.588638 0.993862139 1.058574742 1.090754693 0.977115063 1.932413378 2.954875526 1.028375173 0.338811047 1.638107342 1 11.52531948 -5.778373284 24.73873379 1.008712038 1.624762555 0.07773167 0.654205592 277.6798948 405662.1028 0.093065795 0.16902236 1.67E-06 5.778373284 0.616050517 SLS(ph)VPDSGR ddPTM_HeLa_Curcumin_4h_R1 1 SLSVPDSGR 9 0 O75420 O75420 GIGYF1 PERQ amino acid-rich with GYF domain-containing protein 1 1 0 S(0.001)LS(0.999)VPDSGR 112.85 0.0082312 70980000 4007.7 2960 3895.8 4015.3 3743.8 4625 3540.5 5736.9 3262 3119.2 TRUE FALSE FALSE 3690.486316 3215.84921 4040.181775 3998.685753 3699.15763 3665.722866 3639.836901 7486.054401 2904.166761 3227.591968 1.143417865 0.996361759 1.251763487 1.238906836 1.146104485 1.135745442 1.127725232 2.319393057 0.899793651 1 11.65624249 -4.261117971 6.124921709 1.099622114 2.350108149 0.924558485 0.104140361 0.022340547 4.236149565 0.013471584 0.115461866 5.48E-05 4.261117971 1.250486035 SLS(ph)VPVDLSR ddPTM_HeLa_Curcumin_4h_R1 1 SLSVPVDLSR 10 0 Q9NYF3;D6RHW3 Q9NYF3 FAM53C Protein FAM53C 1 0 S(0.224)LS(0.765)VPVDLS(0.011)R 111.5 0.0069623 35838000 4494.6 3130.9 4096.9 3641.3 4235.5 5980.5 4019.2 4177.6 3981.9 3655.7 TRUE FALSE FALSE 4138.847667 3401.521045 4248.734718 3626.233265 4184.994429 4740.076886 4131.967935 5451.331009 3545.095532 3782.735303 1.094141497 0.899222592 1.123191124 0.958627283 1.106340807 1.253081833 1.092322778 1.441108238 0.937177796 1 11.88521411 -1 0.593432302 1.034592627 23.59787759 0.650601363 0.090877704 68.17789124 0.496682065 0.014478422 1997.069094 0.1 1 22.56328497 SLS(ph)YEEPR ddPTM_HeLa_Curcumin_4h_R1 1 SLSYEEPR 8 0 F5GZK9;Q8IZD4-2;Q8IZD4 F5GZK9 DCP1B mRNA-decapping enzyme 1B 1 0 S(0.005)LS(0.995)YEEPR 109.83 0.011345 134260000 2853.2 2092.1 2598.8 2470.2 2186.5 3022 2798 1574.7 2244.9 1935.8 TRUE FALSE FALSE 2627.366209 2272.931802 2695.113814 2459.978967 2160.427416 2395.203135 2876.50435 2054.818781 1998.640086 2003.068906 1.311670408 1.134724719 1.345492312 1.228105014 1.07855871 1.19576672 1.436048626 1.025835294 0.997788983 1 10.96799634 -9.437892609 1.112904276 0.997185489 1.231051207 0.356045369 0.117485374 0.439416277 0.954474806 0.081280177 0.019343996 3.65E-10 9.437892609 0.233865718 SLS(ph)YSPVER ddPTM_HeLa_Curcumin_4h_R1 1 SLSYSPVER 9 0 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.296)LS(0.598)Y(0.002)S(0.104)PVER 121.29 0.0059019 46011000 1400.9 1233.7 1216.8 1436.4 1266.7 1460.5 1433.8 2280.1 1429.8 1449.9 TRUE FALSE FALSE 1290.017287 1340.335531 1261.895678 1430.456557 1251.59543 1157.575837 1474.028569 2975.291994 1272.954517 1500.283917 0.859848774 0.893387922 0.841104583 0.953457236 0.83423905 0.771571183 0.982499747 1.983152629 0.848475747 1 10.55101983 -4.263814379 4.672656141 0.907574878 2.045785294 0.960007478 0.067160074 0.02875352 1.699312706 0.010839601 0.106303106 5.45E-05 4.263814379 1.138210416 SLSAIYLEK ddPTM_HeLa_Curcumin_4h_R1 2 SLSAIYLEK 9 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 149.72 4.09E-06 3075600 2397.13 1708.82 1751.99 2035.12 2078.04 2070.75 1983 1632.16 2161.35 2113.89 FALSE FALSE TRUE 2207.394631 1856.522786 1816.920291 2026.699213 2053.26073 1641.253108 2038.637643 2129.79807 1924.255312 2187.34752 1.009165032 0.848755293 0.830650033 0.926555654 0.938698909 0.750339437 0.932013603 0.973689846 0.879720892 1 11.09496673 -7.270598018 24.34933759 1.004327937 0.883860229 0.122271717 0.072580175 295.8579634 786572.3511 0.010197818 0.011744865 5.36E-08 7.270598018 -0.120467707 SLSAS(ph)PALGSTK ddPTM_HeLa_Curcumin_4h_R1 1 SLSASPALGSTK 12 0 O95544;O95544-2 O95544 NADK NAD kinase 1 0 S(0.05)LS(0.239)AS(0.711)PALGSTK 161.25 0.00018951 60022000 4345.6 3965.7 4067.5 4249.9 4075.5 4879.1 4472.5 4565.6 4983.4 5135.3 TRUE FALSE FALSE 4001.641175 4308.477437 4218.245128 4232.31504 4026.902324 3867.119661 4597.986313 5957.630423 4436.733488 5313.751293 0.753072727 0.81081654 0.793835634 0.796483465 0.757826647 0.727756993 0.865299496 1.121172237 0.83495317 1 12.37551499 -9.418907225 1.127073505 1.000790205 0.815206298 0.003174982 0.116746864 0.510757496 1.152626523 0.07462435 0.018510726 3.81E-10 9.418907225 -0.185583908 SLSDNGQPGT(ph)PDPADSGGTSAK ddPTM_HeLa_Curcumin_4h_R1 3 SLSDNGQPGTPDPADSGGTSAK 22 0 O75691 O75691 UTP20 Small subunit processome component 20 homolog 1 0 SLSDNGQPGT(1)PDPADSGGTSAK;SLSDNGQPGT(1)PDPADSGGTSAK;S(0.001)LS(0.003)DNGQPGT(0.996)PDPADSGGTSAK ;; 163.31 1.28E-07 48131700 8590.9 6855 7150.7 7907.5 7404.1 9915.6 7279.1 5077.7 9709.3 7984.6 TRUE FALSE FALSE 7910.9212 7447.515655 7415.711232 7874.78086 7315.810943 7858.992788 7483.331955 6625.867355 8644.214081 8262.064256 0.957499356 0.901411006 0.897561554 0.953125105 0.88547011 0.951214194 0.905746037 0.8019627 1.046253553 1 13.01228657 -1 0.093190066 1.065142713 0.487195298 0.642716227 0.038268965 68.15652147 0.458026257 0.36470326 5.057216765 0.1 1 -0.577947415 SLSDS(ph)ESDDSK ddPTM_HeLa_Curcumin_4h_R1 3 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 0 SLS(0.037)DS(0.827)ES(0.136)DDSK;SLSDS(0.922)ES(0.077)DDSK;S(0.005)LS(0.001)DS(0.99)ES(0.004)DDSK ;; 193.15 2.94E-05 123018000 9931.6 9273.8 9808.1 9974.2 10475.9 10650.7 8846 7087.9 9192.8 9299.4 TRUE FALSE FALSE 9145.50338 10075.38595 10171.59681 9932.929403 10350.98173 8441.624762 9094.194952 9248.968081 8184.372839 9622.553458 0.950423754 1.047059493 1.057057969 1.03225505 1.075700102 0.877274914 0.945091653 0.961176066 0.850540647 1 13.23220407 -5.247627084 24.9627093 0.9976965 0.929571963 0.21671555 0.064116204 832.1211621 1503874.494 0.007321488 0.018564818 5.65E-06 5.247627084 -0.068124537 SLSDS(ph)ESDDSKSK ddPTM_HeLa_Curcumin_4h_R1 1 SLSDSESDDSKSK 13 1 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 0 SLS(0.106)DS(0.726)ES(0.101)DDS(0.046)KS(0.021)K 111.66 0.0029336 0 1053.1 1232.4 1252.7 965.73 908.13 1230.3 802.61 687.75 1259.2 954.21 TRUE FALSE FALSE 969.7460238 1338.923165 1299.126164 961.7340651 897.3011429 975.1219117 825.1290765 897.441809 1121.06891 987.3687265 0.982151852 1.356051826 1.315745708 0.974037398 0.908780194 0.987596513 0.83568484 0.90892266 1.135410592 1 9.94744514 -6.004498238 24.30579417 1.050868707 0.914315672 0.306894206 0.13761037 210.0419304 1134959.169 0.023310288 0.041469108 9.90E-07 6.004498238 -0.136553035 SLSDSESDDSK ddPTM_HeLa_Curcumin_4h_R1 1 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 0 0 150.1 0.0053435 13855000 2765.8 2493.8 2453.5 2336.3 2849.7 2917.1 2287.4 2235.2 2433 2100.3 FALSE FALSE TRUE 2546.884012 2709.35296 2544.428868 2326.63301 2815.719189 2312.060578 2351.578288 2916.70219 2166.105987 2173.285269 1.171905064 1.246662368 1.170775372 1.070560337 1.295604967 1.063855082 1.08203848 1.342070566 0.996696577 1 11.08566184 -9.049620081 0.76809837 0.995804589 1.175317592 0.393250128 0.089609191 0.589089791 0.615456122 0.062607679 0.017509426 8.92E-10 9.049620081 0.179513003 SLSLASTSRDS(ph)PGAVAAPLISGVEIK ddPTM_HeLa_Curcumin_4h_R1 2 SLSLASTSRDSPGAVAAPLISGVEIK 26 1 Q5THJ4-2;Q5THJ4;H3BLS7;A0A2R8YD87 Q5THJ4-2 VPS13D Vacuolar protein sorting-associated protein 13D 1 0 SLS(0.002)LAS(0.064)T(0.064)S(0.064)RDS(0.806)PGAVAAPLISGVEIK;SLSLAS(0.001)T(0.001)S(0.006)RDS(0.991)PGAVAAPLISGVEIK ; 132.48 2.62E-08 46214000 3231.5 3539.4 3180 3197 2916.4 3503.8 3040.9 2449.49 3642.6 2985.5 TRUE FALSE FALSE 2975.723365 3845.329965 3297.853597 3183.771661 2881.623835 2777.072384 3126.21947 3196.328225 3243.015893 3089.245903 0.963252347 1.244747128 1.06752706 1.030598328 0.93279199 0.89894831 1.011968477 1.034662932 1.049775899 1 11.593039 -4.515416883 24.74577351 1.000844177 1.028989347 0 0.091473928 1549.909401 5139909.213 0.013078371 0.053939995 3.05E-05 4.515416883 0.028145169 S(ph)IELEHFEER ddPTM_HeLa_Curcumin_4h_R1 2 SIELEHFEER 10 0 G5E9L9;Q8N568-2;Q8N568;A0A0U1RR70;Q8N568-3 G5E9L9 DCLK2 Serine/threonine-protein kinase DCLK2 1 0 S(1)IELEHFEER;S(1)IELEHFEER ; 133.98 0.0011138 18063300 10448.3 8967.2 8167 9524.8 8995.4 9384.4 6271.1 2972 10227.8 9833.5 TRUE FALSE FALSE 9621.30603 9742.284811 8469.676204 9485.388901 8888.13573 7437.969656 6447.050188 3878.149119 9105.835929 10175.21339 0.945563072 0.957452629 0.832383153 0.932205403 0.873508534 0.730989058 0.633603438 0.381136883 0.894903682 1 13.31277143 -4.190992471 0.622896783 0.970127216 1.14E-14 0.931356686 0.047124131 0.517792464 0.128888704 0.007597734 0.365124637 6.44E-05 4.190992471 -0.970127216 down SLSMDS(ph)QVPVYSPSIDLK ddPTM_HeLa_Curcumin_4h_R1 1 SLSMDSQVPVYSPSIDLK 18 0 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 0 S(0.018)LS(0.113)MDS(0.869)QVPVYSPSIDLK 215.51 6.22E-17 28746000 2165.1 1806.8 1918.4 1882.4 1716.5 2014.8 1864.4 1452.6 2041.1 1679.5 TRUE FALSE FALSE 1993.73005 1962.971741 1989.497592 1874.611128 1696.031859 1596.907769 1916.710046 1895.491053 1817.196437 1737.8625 1.147231182 1.129532251 1.144795743 1.078687829 0.975929833 0.918891897 1.102912369 1.090702546 1.045650295 1 10.76309823 -5.868292633 9.193625567 1.083145675 1.020604754 0.206278154 0.065124904 0.467540885 37.03981316 0.011894158 0.021595862 1.35E-06 5.868292633 -0.06254092 SRT(ph)GS(ph)ESSQTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 2 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 0 S(0.032)RT(0.977)GS(0.74)ES(0.238)S(0.013)QTGTSTTSSR;S(0.013)RT(0.968)GS(0.896)ES(0.06)S(0.048)QT(0.013)GT(0.001)S(0.001)TTSSR ; 119.72 0.00058113 121378300 6296.8 4363.1 5351.4 5667.5 5756.9 6326.7 4183 1432.41 6721.2 5167.9 TRUE FALSE FALSE 5798.401636 4740.226922 5549.727592 5644.049387 5688.252727 5014.471103 4300.363722 1869.145215 5983.901176 5347.48414 1.084323297 0.886440576 1.037820299 1.055458836 1.06372503 0.937725288 0.804184474 0.349537309 1.119012421 1 12.38464458 -4.190743014 1.452147822 1.030851278 4.72E-13 0.920541318 0.060737132 0.250009745 0.414734887 0.008348318 0.389292773 6.45E-05 4.190743014 -1.030851278 down SLSPGAAS(ph)SSSGDGDGKEGLEEPK ddPTM_HeLa_Curcumin_4h_R1 1 SLSPGAASSSSGDGDGKEGLEEPK 24 1 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 0 SLS(0.004)PGAAS(0.421)S(0.076)S(0.076)S(0.421)GDGDGKEGLEEPK 89.831 2.83E-05 13867000 3006 2689.4 3017.2 2811.6 2507 2640.5 2183.6 1715.9 2626.4 2883.3 TRUE FALSE FALSE 2768.071928 2921.859752 3129.020086 2799.966344 2477.105662 2092.830535 2244.865939 2239.070011 2338.290491 2983.49446 0.92779523 0.979341437 1.048776905 0.938485518 0.830269905 0.701469556 0.752428392 0.750485728 0.783742193 1 11.54278738 -5.636790297 2.637915513 0.972483194 0.737680598 0.651794847 0.068399208 0.065673223 0.922487346 0.005913122 0.013076944 2.31E-06 5.636790297 -0.234802596 SLSS(ph)PTDNLELSLR ddPTM_HeLa_Curcumin_4h_R1 2 SLSSPTDNLELSLR 14 0 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 0 SLS(0.043)S(0.889)PT(0.068)DNLELS(0.001)LR;SLS(0.007)S(0.969)PT(0.024)DNLELSLR ; 236.05 3.40E-21 38237700 4264.66 2989.24 3290.64 3133.33 3292.79 4438.46 3148.49 5966.3 4133.49 3566.43 TRUE FALSE FALSE 3927.107661 3247.616586 3412.594013 3120.365111 3253.52563 3517.873364 3236.828156 7785.397405 3680.056488 3690.363177 1.064152083 0.880026282 0.924731212 0.845544181 0.881627491 0.953259394 0.877102876 2.109656159 0.997207134 1 11.84954709 -4.258302953 24.96691364 0.978779999 2.109656583 0.954039769 0.076767048 53.92547245 429241.6686 0.013218435 0.125798367 5.52E-05 4.258302953 1.130876583 SLSS(ph)PTVTLSAPLEGAK ddPTM_HeLa_Curcumin_4h_R1 1 SLSSPTVTLSAPLEGAK 17 0 A0A1B0GVY1;Q96PU5-9;Q96PU5-4;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-7;Q96PU5 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 0 S(0.079)LS(0.263)S(0.656)PT(0.002)VTLSAPLEGAK 171.15 5.77E-05 414660000 5652.4 4884.8 5187.3 5602.4 5085.2 5741.5 4015.9 2869.6 5943.3 4785.8 TRUE FALSE FALSE 5205.006576 5307.020346 5379.545901 5579.218753 5024.562311 4550.64818 4128.575346 3744.52783 5291.334859 4952.106194 1.051069257 1.071669334 1.08631473 1.126635523 1.014631374 0.918931865 0.833700891 0.756148532 1.068501896 1 12.27382654 -4.893507528 1.714491066 1.040910816 0.766379851 0.889309906 0.037832207 0.119634347 0.638407948 0.00669725 0.036010666 1.28E-05 4.893507528 -0.274530965 SLSS(ph)SLDDTEVKK ddPTM_HeLa_Curcumin_4h_R1 1 SLSSSLDDTEVKK 13 1 O95292 O95292 VAPB Vesicle-associated membrane protein-associated protein B/C 1 0 S(0.007)LS(0.047)S(0.675)S(0.269)LDDT(0.003)EVKK 94.454 0.0046336 10296000 3217.4 2847.4 2590 4378.4 3216 4020.4 2249.3 1450.5 5028.7 3401.8 TRUE FALSE FALSE 2962.739395 3093.516568 2685.987678 4360.283341 3177.6513 3186.523721 2312.409304 1892.750773 4477.064191 3520.012297 0.841684388 0.878836864 0.763062016 1.238712531 0.902738693 0.905259258 0.656932167 0.537711409 1.271888793 1 11.78136475 -4.668627104 2.665276597 0.93029837 0.547603881 0.461170864 0.160150292 0.160029963 2.148521784 0.017110296 0.091376733 2.14E-05 4.668627104 -0.382694489 SLSS(ph)SPVKK ddPTM_HeLa_Curcumin_4h_R1 1 SLSSSPVKK 9 1 Q9H3Q1;Q9H3Q1-2 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 0 SLS(0.166)S(0.746)S(0.088)PVKK 97.452 0.0068541 637120000 7384.3 6371.4 5392.7 7094.1 7879.3 11115 8341 12127 9499.7 8655 TRUE FALSE FALSE 6799.824863 6922.115426 5592.558206 7064.746494 7785.344494 8809.623708 8575.026011 15824.46647 8457.606677 8955.760606 0.75926827 0.772923231 0.624464906 0.788849413 0.869311367 0.983682358 0.957487185 1.766959521 0.944376145 1 13.12860025 -3.687231698 1.416860637 0.849642865 4.337920259 0.863862195 0.109281135 1.711900749 0.967923189 0.019431001 12.70630004 0.000205479 3.687231698 3.488277394 SLSSPPSSK(ac)RPK ddPTM_HeLa_Curcumin_4h_R1 2 SLSSPPSSKRPK 12 2 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 0 1 ; SLSSPPSSK(1)RPK;SLSSPPSSK(1)RPK 91.202 0.0043235 6577500 2204.8 2062.73 1946.88 1638.37 1968.13 2946.5 1985.61 575.27 2405.04 1933.14 FALSE TRUE FALSE 2030.287754 2241.02319 2019.033085 1631.590859 1944.661335 2335.362686 2041.320873 750.6671748 2141.213129 2000.316471 1.01498327 1.120334318 1.009356827 0.815666362 0.972176835 1.167496604 1.020498957 0.375274206 1.070437183 1 10.96601255 -4.260927634 24.85056588 1.011188665 0.375273996 0.82432359 0.089350911 11.4174965 554267.8551 0.011991111 0.094941043 5.48E-05 4.260927634 -0.635914668 SLSSS(ph)LDDTEVKK ddPTM_HeLa_Curcumin_4h_R1 1 SLSSSLDDTEVKK 13 1 O95292 O95292 VAPB Vesicle-associated membrane protein-associated protein B/C 1 0 S(0.002)LS(0.065)S(0.065)S(0.858)LDDT(0.011)EVKK 85.576 0.0078364 12562000 3356 3238.4 3218.7 4818 3404 4427.2 2480.3 1226.7 4747 3640.4 TRUE FALSE FALSE 3090.369059 3518.312866 3337.987853 4798.064393 3363.409523 3508.948815 2549.890543 1600.715183 4226.265976 3766.903629 0.820400351 0.934006604 0.886135718 1.273742274 0.89288441 0.931520729 0.676919506 0.424941899 1.121946934 1 11.87916341 -4.488158026 2.10211035 0.939143632 0.390031357 0.648938509 0.130213164 0.21626328 1.455220608 0.01789477 0.186814695 3.25E-05 4.488158026 -0.549112275 SLSSS(ph)PQAQPPRPAELSDEEVAELFQR ddPTM_HeLa_Curcumin_4h_R1 1 SLSSSPQAQPPRPAELSDEEVAELFQR 27 1 A0A087WXA6;A0A087WT45;Q4V328-4;Q4V328 A0A087WXA6 GRIPAP1 GRIP1-associated protein 1 1 0 S(0.004)LS(0.069)S(0.346)S(0.413)PQAQPPRPAELS(0.168)DEEVAELFQR 56.474 0.0022242 106930000 1016.9 411.9 783.7 735.28 524.67 830.57 495.52 695.62 1106.2 922.51 TRUE FALSE FALSE 936.411292 447.5028006 812.7446114 732.2376062 518.4136529 658.3004195 509.4229576 907.7113358 984.8526276 954.5671538 0.980980006 0.468801801 0.851427381 0.767088626 0.543087672 0.689632381 0.533669062 0.950914068 1.031726918 1 9.898702885 -7.347949832 9.727068144 0.991366872 0.684666361 0.51831024 0.140262219 0.247415563 26.54945432 0.021819472 0.024925435 4.49E-08 7.347949832 -0.306700511 SLSSSPQAQPPRPAELS(ph)DEEVAELFQR ddPTM_HeLa_Curcumin_4h_R1 1 SLSSSPQAQPPRPAELSDEEVAELFQR 27 1 A0A087WXA6;A0A087WT45;Q4V328-4;Q4V328 A0A087WXA6 GRIPAP1 GRIP1-associated protein 1 1 0 S(0.009)LS(0.025)S(0.091)S(0.338)PQAQPPRPAELS(0.538)DEEVAELFQR 87.748 9.07E-06 47250000 1141 941.32 1184 1005.6 751.13 839.22 746.58 1282.7 1187.8 1024.3 TRUE FALSE FALSE 1050.688646 1022.683506 1227.880082 1001.439094 742.1732653 665.156312 767.5270255 1673.789325 1057.501312 1059.894349 0.991314509 0.964891932 1.158492904 0.944848036 0.700233251 0.627568505 0.724154277 1.579203934 0.997742193 1 10.04970475 -5.996083962 24.88350406 1.006131494 0.868142752 0.033716213 0.252517816 254.6709465 1618215.027 0.035418809 0.063987229 1.01E-06 5.996083962 -0.137988742 SLSYS(ph)PVER ddPTM_HeLa_Curcumin_4h_R1 4 SLSYSPVER 9 0 Q9UQ35;Q9UQ35-2;I3L4U6 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.31)LS(0.059)YS(0.631)PVER;S(0.004)LS(0.076)YS(0.92)PVER;S(0.009)LS(0.035)YS(0.956)PVER;S(0.011)LS(0.076)YS(0.913)PVER ;;; 140.78 0.0023335 313507000 15327.7 12059.6 13565.4 13152.2 12725.5 16513.1 12503.9 12783.7 15706.4 12371.6 TRUE FALSE FALSE 14114.49637 13101.97809 14068.14566 13097.77968 12573.75672 13088.09692 12854.72578 16681.39128 13983.44722 12801.51218 1.102564773 1.023471126 1.098944051 1.023143164 0.982208707 1.022386788 1.004156822 1.303079749 1.092327767 1 13.64402662 -4.256486164 24.80646609 1.040987528 1.30307987 0.784561047 0.041532159 183.0047863 916482.0914 0.00651052 0.071966104 5.54E-05 4.256486164 0.262092343 SLT(ph)PPPSSTESK ddPTM_HeLa_Curcumin_4h_R1 2 SLTPPPSSTESK 12 0 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 1 0 S(0.069)LT(0.931)PPPSSTESK;S(0.003)LT(0.997)PPPSSTESK ; 128.57 0.0077007 164631000 8219.8 6818 7002 7325.2 7253.8 7944.4 6333.8 3496 9167.5 7011.3 TRUE FALSE FALSE 7569.194157 7407.31754 7261.50028 7294.890263 7167.303173 6296.641888 6511.509381 4561.914306 8161.848186 7254.942153 1.043315577 1.021002977 1.000903953 1.005506331 0.987920099 0.867910695 0.897527402 0.628800921 1.125005274 1 12.8247484 -3.648459162 0.731360577 1.019908122 1.20E-19 0.873785656 0.045778454 1.007686055 0.203595021 0.005079375 1.043812937 0.000224668 3.648459162 -1.019908122 SLT(ph)S(ph)IIEYYY(ph)MWKT(ph)T(ph)DRYVQQK ddPTM_HeLa_Curcumin_4h_R1 1 SLTSIIEYYYMWKTTDRYVQQK 22 2 F6RRE2;E7EV10;Q9BTC8;E7EQY4;Q9BTC8-2;E9PCS8;H0Y4T7;E7ESY4;Q13330-3;Q13330;Q13330-2 F6RRE2;H0Y4T7 MTA3;MTA1 Metastasis-associated protein MTA3;Metastasis-associated protein MTA1 5 0 S(0.176)LT(0.524)S(0.524)IIEY(0.559)Y(0.287)Y(0.936)MWKT(0.889)T(0.578)DRY(0.527)VQQK 40.968 0.014201 37003000 5623.4 4889.8 5051 5614 5383.1 7060.3 4996.2 5024.9 5803.5 5060.7 TRUE FALSE FALSE 5178.301956 5312.452523 5238.194503 5590.770756 5318.910048 5595.914194 5136.379925 6556.968878 5166.87057 5236.558948 0.988874948 1.014493024 1.000312334 1.067642093 1.015726186 1.06862431 0.980869303 1.252152213 0.986691952 1 12.35440338 -4.25774379 24.96110282 1.006825811 1.252152309 0.847307143 0.030242427 96.32253248 650562.5809 0.004265585 0.042245018 5.52E-05 4.25774379 0.245326498 SLTEISTDFDRS(ph)SPPLQPPPVNSLTTENR ddPTM_HeLa_Curcumin_4h_R1 1 SLTEISTDFDRSSPPLQPPPVNSLTTENR 29 1 J3KRR7;Q9NQC7-2;Q9NQC7 J3KRR7 CYLD Ubiquitin carboxyl-terminal hydrolase CYLD 1 0 SLTEISTDFDRS(0.5)S(0.5)PPLQPPPVNSLTTENR 124.1 1.18E-12 57435000 1738.5 1538.6 1796.9 1588.7 1527.3 2177 1679.7 884.32 2030.5 1695.4 TRUE FALSE FALSE 1600.895891 1671.589728 1863.494695 1582.12638 1509.087945 1725.46566 1726.827861 1153.945097 1807.75923 1754.315024 0.912547558 0.952844675 1.062234929 0.901848504 0.860214913 0.983555198 0.984331684 0.657775303 1.030464429 1 10.77669212 -4.258254396 24.95197571 0.957027401 0.65777519 0.71208693 0.058455827 122.9714015 963340.9151 0.007886351 0.075413248 5.52E-05 4.258254396 -0.299252211 SLTEISTDFDRSS(ph)PPLQPPPVNSLTTENR ddPTM_HeLa_Curcumin_4h_R1 1 SLTEISTDFDRSSPPLQPPPVNSLTTENR 29 1 J3KRR7;Q9NQC7-2;Q9NQC7 J3KRR7 CYLD Ubiquitin carboxyl-terminal hydrolase CYLD 1 0 SLTEIST(0.001)DFDRS(0.389)S(0.609)PPLQPPPVNSLTTENR 97.388 3.19E-08 51814000 1031.1 1233.1 1069.9 953.6 1133.6 1458 1160 431.28 1301.6 1310.1 TRUE FALSE FALSE 949.487347 1339.683669 1109.551435 949.6542559 1120.08256 1155.594365 1192.546478 562.7752866 1158.817736 1355.625877 0.700405151 0.988239965 0.81847909 0.700528274 0.82624755 0.852443424 0.879701766 0.415140561 0.854821198 1 10.40474337 -13.52287873 0.31944548 3.251605237 0.761443243 0.115222304 0.150609986 50.01747718 0.674294466 73.06381531 0.052080959 3.00E-14 13.52287873 -2.490161995 SLTLSFVS(ph)ER ddPTM_HeLa_Curcumin_4h_R1 1 SLTLSFVSER 10 0 Q86V48-2;Q86V48-3;Q86V48;E5RFK8 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 SLTLS(0.413)FVS(0.587)ER 93.111 0.017149 1005800 448.63 424.38 1205.9 731.5 2121.2 2512.8 1411.1 1280.3 1618.1 819.67 TRUE FALSE FALSE 413.1204621 461.0615162 1250.591715 728.4732468 2095.906075 1991.616955 1450.691668 1670.657576 1440.598478 848.1534715 0.487082204 0.543606236 1.474487527 0.858893197 2.471140125 2.348179925 1.710411756 1.969758578 1.698511563 1 9.728181531 -5.773159736 24.51474837 0.800344292 2.111218712 0.59673851 0.428353007 61.20558521 128020.1324 0.053276454 0.097168968 1.69E-06 5.773159736 1.31087442 SLTNDWEDHLAVK ddPTM_HeLa_Curcumin_4h_R1 4 SLTNDWEDHLAVK 13 0 P08238;P07900;P07900-2 P08238;P07900 HSP90AB1;HSP90AA1 Heat shock protein HSP 90-beta;Heat shock protein HSP 90-alpha 0 0 ;;; ;;; 140.31 0.00017447 345107600 23362.7 22256.6 19443.6 21815.1 20647.4 23087.2 18281.8 18567.3 24078.6 21128.6 FALSE FALSE TRUE 21513.51764 24180.36133 20164.19692 21724.8349 20401.19324 18298.65447 18794.73811 24228.3843 21437.23782 21862.81728 0.984023119 1.106003907 0.922305514 0.993688719 0.933145668 0.836976051 0.859666797 1.108200466 0.980534098 1 14.4161917 -5.735508496 4.488318476 0.996183587 0.920986734 0.123408375 0.079888541 0.272624723 12.74390944 0.011023322 0.02193236 1.84E-06 5.735508496 -0.075196852 SLTNPT(ph)PIQQQLR ddPTM_HeLa_Curcumin_4h_R1 4 SLTNPTPIQQQLR 13 0 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 0 SLT(0.002)NPT(0.998)PIQQQLR;SLT(0.139)NPT(0.861)PIQQQLR;S(0.002)LTNPT(0.998)PIQQQLR;S(0.128)LT(0.007)NPT(0.864)PIQQQLR ;;; 196.37 5.51E-09 67548200 7591.6 7351.7 7804.7 7125.2 8253.9 11177.7 8505.4 3526.17 8841.8 8413 TRUE FALSE FALSE 6990.716849 7987.148189 8093.949048 7095.71781 8155.477633 8859.319021 8744.038633 4601.283001 7871.876661 8705.351124 0.803036747 0.917498683 0.929767098 0.815098404 0.936835002 1.017686581 1.004444107 0.528558002 0.904257226 1 13.08768677 -9.563283174 1.339289446 0.99996873 0.872395938 0.0392882 0.135057788 0.774534869 2.490710064 0.088947999 0.020945943 2.73E-10 9.563283174 -0.127572792 SLTS(ph)SLENIFSR ddPTM_HeLa_Curcumin_4h_R1 2 SLTSSLENIFSR 12 0 A0A3B3IRT3;O60343-2;O60343-3;O60343;Q5JU47 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 1 0 S(0.304)LT(0.043)S(0.651)S(0.003)LENIFSR;S(0.002)LT(0.006)S(0.496)S(0.496)LENIFSR ; 260.5 2.91E-36 188213000 8517.2 6625.2 7291.6 6913.5 6770.8 10175.9 7303.6 2123.29 8489.2 7307.9 TRUE FALSE FALSE 7843.054633 7197.852767 7561.83311 6884.893769 6690.062632 8065.303634 7508.519359 2770.671347 7557.955999 7561.848981 1.03718742 0.951864125 0.999997901 0.910477555 0.884712542 1.066578247 0.992947542 0.366401307 0.999485181 1 12.88452332 -4.261572698 8.093237744 0.998542927 0.361575227 0.921242653 0.053869982 0.017987903 15.04222796 0.007904943 0.06244149 5.48E-05 4.261572698 -0.636967699 SLTSS(ph)LENIFSR ddPTM_HeLa_Curcumin_4h_R1 2 SLTSSLENIFSR 12 0 A0A3B3IRT3;O60343-2;O60343-3;O60343;Q5JU47 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 1 0 SLTS(0.068)S(0.932)LENIFSR;SLT(0.005)S(0.316)S(0.679)LENIFSR ; 231.69 4.10E-19 204375000 6621.5 5489 5137.1 5198.2 5069.1 7119.5 5796.2 1314.73 6629.7 5199.7 TRUE FALSE FALSE 6097.401288 5963.444701 5327.485445 5176.691226 5008.654293 5642.835447 5958.825772 1715.585125 5902.438497 5380.389188 1.133263984 1.108366792 0.990167302 0.962140664 0.930909293 1.048778304 1.107508317 0.318858927 1.097028168 1 12.39349482 -4.258597605 24.98032973 1.048045439 0.318858662 0.91517292 0.06602675 61.14729283 537479.664 0.010712059 0.100065864 5.51E-05 4.258597605 -0.729186777 SLTVSDDAES(ph)SEPER ddPTM_HeLa_Curcumin_4h_R1 1 SLTVSDDAESSEPER 15 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 SLTVSDDAES(0.69)S(0.31)EPER 207.64 6.00E-32 0 1747.5 1311.2 1800.2 1389.7 1377.4 1696.8 1427.2 796.73 1683.1 1460.9 TRUE FALSE FALSE 1609.183531 1424.534285 1866.916996 1383.94979 1360.975405 1344.864553 1467.243391 1039.649309 1498.468141 1511.666166 1.064509855 0.942360368 1.235006139 0.915512843 0.900314788 0.88965711 0.970613369 0.687750598 0.99126922 1 10.56192386 -6.020264336 24.56516153 1.038829488 0.876319071 0.440608729 0.098703567 439.0380806 532218.1284 0.013540323 0.022650134 9.54E-07 6.020264336 -0.162510417 SLTVSDDAESS(ph)EPER ddPTM_HeLa_Curcumin_4h_R1 3 SLTVSDDAESSEPER 15 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 SLTVSDDAES(0.026)S(0.974)EPER;SLTVSDDAES(0.225)S(0.775)EPER;SLT(0.007)VS(0.11)DDAES(0.198)S(0.686)EPER ;; 275.42 5.51E-114 50262700 8709.4 7534.3 8404.1 8708.5 7491.3 9801.4 8169.4 4665.9 8662.8 7994 TRUE FALSE FALSE 8020.0418 8185.53132 8715.563339 8672.466534 7401.97114 7768.479155 8398.611377 6088.511431 7712.512513 8271.790905 0.969565345 0.989571837 1.053648894 1.048438801 0.894845049 0.939153231 1.015331683 0.736057222 0.932387267 1 13.013984 -4.257412745 24.76880361 0.986680043 0.73605711 0.70117689 0.048206594 140.0442621 861407.0595 0.006289371 0.064369657 5.53E-05 4.257412745 -0.250622933 SLVEIADTVPK ddPTM_HeLa_Curcumin_4h_R1 1 SLVEIADTVPK 11 0 H0Y8C6;O00410-2;O00410;O00410-3 H0Y8C6 IPO5 Importin-5 0 0 108.43 0.0051098 2472900 629.08 348.63 564.22 409.13 411.51 598.16 405.95 424.31 513.32 777.42 FALSE FALSE TRUE 579.2876542 378.7640237 585.1304895 407.4371285 406.603012 474.0948733 417.3398644 553.6801657 457.0100803 804.4352871 0.72011716 0.470844616 0.727380436 0.506488384 0.505451487 0.589351165 0.518798555 0.688284284 0.56811292 1 9.651832558 -8.293250583 0.583732147 0.997068657 0.558039713 0 0.154322013 0.233855154 0.174322017 0.045915731 0.022728625 5.09E-09 8.293250583 -0.439028943 SLVESVSS(ph)SPNKESNEEEQVWHFLGK ddPTM_HeLa_Curcumin_4h_R1 1 SLVESVSSSPNKESNEEEQVWHFLGK 26 1 Q9H2U2-4;Q9H2U2-6;Q9H2U2-3;Q9H2U2;Q9H2U2-2 Q9H2U2-4 PPA2 "Inorganic pyrophosphatase 2, mitochondrial" 1 0 S(0.002)LVES(0.009)VS(0.127)S(0.447)S(0.385)PNKES(0.029)NEEEQVWHFLGK 72.566 0.00016963 149430000 4573.6 3579.6 3385.5 3479.6 4187.2 5406.3 4073.1 3121.7 4190.8 3953.1 TRUE FALSE FALSE 4211.594734 3889.004674 3510.969608 3465.202337 4137.270375 4284.972438 4187.380224 4073.491959 3731.079725 4090.469931 1.029611464 0.95074765 0.858329157 0.847140401 1.011441337 1.047550162 1.023691726 0.995849384 0.912139629 1 11.99805088 -5.537315862 24.99385922 0.98338634 1.023663141 0.060970888 0.066408286 572.6696284 991414.9186 0.011025263 0.022059147 2.90E-06 5.537315862 0.0402768 SLVESVSSS(ph)PNKESNEEEQVWHFLGK ddPTM_HeLa_Curcumin_4h_R1 1 SLVESVSSSPNKESNEEEQVWHFLGK 26 1 Q9H2U2-4;Q9H2U2-6;Q9H2U2-3;Q9H2U2;Q9H2U2-2 Q9H2U2-4 PPA2 "Inorganic pyrophosphatase 2, mitochondrial" 1 0 S(0.002)LVES(0.022)VS(0.082)S(0.127)S(0.383)PNKES(0.383)NEEEQVWHFLGK 61.985 0.0011739 165090000 4090 3209.2 3181.9 3041.7 3516.5 4715.1 3502.3 3626.5 4118.8 3649 TRUE FALSE FALSE 3766.272184 3486.588948 3299.824013 3029.114251 3474.568034 3737.13511 3600.565112 4732.203156 3666.977945 3775.802478 0.997475955 0.923403427 0.873939787 0.802243833 0.920219756 0.989759165 0.953589371 1.253297328 0.971178436 1 11.88256758 -4.260140367 24.60945482 0.96422665 1.253297442 0.669327702 0.064180942 51.65566094 978459.3746 0.010601742 0.088694484 5.49E-05 4.260140367 0.289070792 SLVPAAELLESR ddPTM_HeLa_Curcumin_4h_R1 1 SLVPAAELLESR 12 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 139.43 0.00015541 4061900 4994.3 4305.3 4157.4 4069 4344.9 4631 3675.6 3690.2 4742.7 3545.3 FALSE FALSE TRUE 4598.995885 4677.430948 4311.476901 4052.163556 4293.089905 3670.478398 3778.727444 4815.324992 4222.437676 3668.498911 1.253645155 1.275025852 1.175270051 1.104583552 1.17025792 1.00053959 1.030047312 1.312614535 1.150998754 1 11.84097414 -4.239919658 22.92924807 1.12597438 1.312615132 0.263177037 0.092085012 2275.858484 2424807.268 0.016219686 0.863068288 5.76E-05 4.239919658 0.186640751 SLVSVTK ddPTM_HeLa_Curcumin_4h_R1 2 SLVSVTK 7 0 P08238;Q58FF7;Q58FF8 P08238 HSP90AB1;HSP90AB3P;HSP90AB2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Putative heat shock protein HSP 90-beta 2 0 0 ; ; 121.99 0.0093304 66477000 25318 19982.4 22573 22972 21930 26652 21783 21942 24670 20459.1 FALSE FALSE TRUE 23314.05358 21709.58962 23409.57524 22876.94795 21668.49907 21124.07477 22394.17235 28632.01479 21963.76272 21170.0522 1.101275205 1.02548588 1.105787318 1.080627848 1.023544905 0.997828185 1.057823199 1.352477288 1.037492138 1 14.36973721 -4.262355188 6.143660239 1.048560143 1.359885382 0.862820119 0.036466836 0.040337725 7.801932651 0.006214763 0.052270818 5.47E-05 4.262355188 0.311325238 SLYAS(ph)SPGGVYATR ddPTM_HeLa_Curcumin_4h_R1 6 SLYASSPGGVYATR 14 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 0 SLYAS(0.5)S(0.5)PGGVYATR;SLYAS(0.5)S(0.5)PGGVYATR;SLYAS(0.5)S(0.5)PGGVYATR;SLYAS(0.5)S(0.5)PGGVYATR;SLYAS(0.52)S(0.48)PGGVYATR;SLYAS(0.991)S(0.009)PGGVYATR ;;;;; 243.3 9.50E-29 12211840000 35867 26288.1 28587.3 29213.7 31985.2 51120.7 44773.1 22612 33037.4 26572.6 TRUE FALSE FALSE 33028.0891 28560.32623 29646.77049 29092.82145 31603.79738 40517.69057 46029.31269 29506.29471 29413.27988 27495.99587 1.201196322 1.038708558 1.078221375 1.058074841 1.149396353 1.473585127 1.674036936 1.073112421 1.069729571 1 14.74693392 -5.338697143 4.611211695 1.089709396 1.433390439 0.503004076 0.146662351 0.127343762 5.000405053 0.020675105 0.048097148 4.58E-06 5.338697143 0.343681043 SLYASS(ph)PGGVYATR ddPTM_HeLa_Curcumin_4h_R1 1 SLYASSPGGVYATR 14 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 0 SLYAS(0.048)S(0.794)PGGVYAT(0.158)R 118.73 0.0018953 10587000 890.21 1494.8 825.12 1009 770.91 1482.4 1241.8 895.31 1104.7 996.54 TRUE FALSE FALSE 819.7489392 1624.003851 855.699673 1004.825025 761.7174017 1174.93353 1276.641566 1168.285897 983.5171738 1031.169691 0.794969971 1.574914261 0.829834004 0.974451668 0.738692582 1.139418216 1.238051872 1.132971525 0.9537879 1 10.01006605 -5.028747665 21.63839361 0.942971175 1.186317669 0.120416708 0.220378931 156.9010024 118101.0122 0.031015078 0.079367743 9.36E-06 5.028747665 0.243346494 SLYASSPGGVYATR ddPTM_HeLa_Curcumin_4h_R1 2 SLYASSPGGVYATR 14 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 0 0 ; ; 229 6.45E-37 43347000 5093.9 3448.7 4089.8 3384.9 3791.5 6722.6 5802.4 5971.2 4381.1 4139.5 FALSE FALSE TRUE 4690.71244 3746.790261 4241.371586 3370.894181 3746.288839 5328.256981 5965.199728 7791.791392 3900.504291 4283.347317 1.095104388 0.87473417 0.99020025 0.786976617 0.874617107 1.243946985 1.392649086 1.819089328 0.910620597 1 12.06452295 -4.500231626 1.519966869 1.001116178 1.922718705 0.864872869 0.109103054 0.212570305 0.624962487 0.017410556 0.254840032 3.16E-05 4.500231626 0.921602526 SLYYYIQQDTK ddPTM_HeLa_Curcumin_4h_R1 4 SLYYYIQQDTK 11 0 P07355;A6NMY6;P07355-2 P07355;P07355-2 ANXA2;ANXA2P2 Annexin A2;Putative annexin A2-like protein 0 0 ;;; ;;; 196.44 1.97E-16 67250900 5121.45 5129.51 4208.82 5848.48 5817.63 6010.25 5742.06 4991.35 6041.4 4003.92 FALSE FALSE TRUE 4716.081828 5572.881988 4364.802572 5824.280539 5748.258562 4763.656401 5903.16675 6513.189638 5378.673535 4143.055922 1.138309962 1.345113871 1.053522485 1.405793368 1.387444116 1.149792928 1.424833954 1.572073793 1.298238217 1 12.01647958 -1 0.115786449 0.860302181 2.841015396 0.278860201 0.148278297 43.42044034 0.348566944 0.55983763 13.87018857 0.1 1 1.980713215 SMDAMS(ph)SPTKTETVK ddPTM_HeLa_Curcumin_4h_R1 1 SMDAMSSPTKTETVK 15 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 1 0 S(0.035)MDAMS(0.521)S(0.443)PT(0.001)KTETVK 59.372 0.01422 176880000 47881 39342 38903 43768 42473 49134 35716 31912 47652 39589 TRUE FALSE FALSE 44091.16833 42742.54718 40344.7794 43586.89961 41966.53722 38943.05455 36718.09484 41641.8219 42424.69482 40964.7148 1.076320647 1.043399115 0.9848666 1.064010816 1.02445574 0.950648741 0.896334687 1.016529032 1.035639941 1 15.32209415 -5.284464507 4.864534202 1.035193125 0.948080016 0.481145761 0.037086161 0.123680603 8.137813698 0.005798968 0.013896665 5.19E-06 5.284464507 -0.08711311 SMDAMSS(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 1 SMDAMSSPTK 10 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 1 0 SMDAMS(0.022)S(0.978)PTK 80.737 0.013389 2444200 3055.5 2856.8 3272.1 2944.4 3622.3 3175.1 2550.9 2677.1 3017.8 2728.2 TRUE FALSE FALSE 2813.653951 3103.729062 3393.366904 2932.216853 3579.106438 2516.548469 2622.471389 3493.335466 2686.75489 2823.004747 0.996687644 1.099441673 1.202040807 1.038686476 1.267835785 0.89144323 0.928964569 1.23745292 0.951735874 1 11.46301584 -7.264850809 23.01635615 0.998435826 1.089483359 0.157860522 0.116715815 158.2188115 1067475.769 0.019010253 0.022221685 5.43E-08 7.264850809 0.091047533 SMDAMSS(ph)PTKTETVK ddPTM_HeLa_Curcumin_4h_R1 3 SMDAMSSPTKTETVK 15 1 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 1 0 S(0.003)MDAMS(0.164)S(0.792)PT(0.033)KT(0.007)ETVK;SMDAMS(0.174)S(0.825)PTKTETVK;SMDAMS(0.118)S(0.881)PT(0.001)KTETVK ;; 185.27 0.00023318 211497000 16794.4 12759.7 13887.3 15657.1 13878.6 16321.8 13331.5 11161.6 17716.6 13730.9 TRUE FALSE FALSE 15465.10552 13862.59161 14401.97555 15592.31507 13713.10676 12936.4747 13705.54601 14564.72046 15773.1333 14208.04775 1.088475052 0.975685883 1.013649152 1.097428397 0.965164743 0.910503323 0.964632598 1.025103569 1.110154863 1 13.79442072 -5.66232553 10.36606983 1.038360816 0.961853684 0.39036263 0.048799173 0.293839556 28.52325954 0.007084964 0.014175456 2.18E-06 5.66232553 -0.076507133 SMDS(ph)SDLSDGAVTLQEYLELKK ddPTM_HeLa_Curcumin_4h_R1 1 SMDSSDLSDGAVTLQEYLELKK 22 1 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QLH1 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 0 S(0.058)MDS(0.47)S(0.47)DLS(0.001)DGAVTLQEYLELKK 145.48 1.06E-05 22982000 1163.6 953.7 1217.4 1532.9 1151.5 1402.6 1069.9 994.05 1404 1247.3 TRUE FALSE FALSE 1071.499832 1036.133578 1262.517915 1526.557266 1137.769115 1111.684949 1099.918515 1297.131269 1249.984713 1290.643582 0.830205835 0.802803805 0.978208029 1.182787632 0.881551755 0.861341555 0.852224836 1.005026707 0.968497213 1 10.33387493 -3.698491417 5.972831608 0.922250593 6.242120279 0.041668284 0.105930678 6788.550474 2309.002786 0.015924307 480551.4817 0.000200221 3.698491417 5.319869686 SMDSS(ph)DLSDGAVTLQEYLELKK ddPTM_HeLa_Curcumin_4h_R1 1 SMDSSDLSDGAVTLQEYLELKK 22 1 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QLH1 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 1 0 S(0.259)MDS(0.325)S(0.408)DLS(0.007)DGAVTLQEYLELKK 130.11 9.68E-06 23286000 661.89 863.61 830.9 723.46 1005.3 1206 1062.6 811.89 960.94 1128.9 TRUE FALSE FALSE 609.5007081 938.2566002 861.6938849 720.4665142 993.3124541 955.8620056 1092.413696 1059.431524 855.5272862 1168.129191 0.521775085 0.803213041 0.737670021 0.616769549 0.850344689 0.818284495 0.935182259 0.906947221 0.732390983 1 10.18998412 -5.073579468 1.835963491 0.759652215 0.921570509 0.238217923 0.120759325 0.666750345 4.236038854 0.026731959 0.10666874 8.44E-06 5.073579468 0.161918293 SMGLPTSDEQK ddPTM_HeLa_Curcumin_4h_R1 1 SMGLPTSDEQK 11 0 Q9Y266 Q9Y266 NUDC Nuclear migration protein nudC 0 0 105.17 0.0061799 2683000 1317.7 1345.4 1083.2 1421.3 1527.1 1834.1 1553 1446.6 1630.2 1327.7 FALSE FALSE TRUE 1213.402655 1461.690381 1123.344345 1415.419037 1508.89033 1453.686985 1596.573 1887.661681 1451.371139 1373.837476 0.883221397 1.063947087 0.817669022 1.030266725 1.09830337 1.05812151 1.162126546 1.374006543 1.056435833 1 10.42399563 -2.834562104 0.54126014 0.945980012 3.15905072 0.693001032 0.079268625 5.313818243 0.324586849 0.013984843 10.54537346 0.001463652 2.834562104 2.213070708 SMGS(ph)QEDDSGNKPSSYS ddPTM_HeLa_Curcumin_4h_R1 4 SMGSQEDDSGNKPSSYS 17 1 H7C3P9;Q9UNS2-2;Q9UNS2 H7C3P9 COPS3 COP9 signalosome complex subunit 3 1 0 S(0.185)MGS(0.815)QEDDSGNKPSSYS;S(0.001)MGS(0.999)QEDDSGNKPSSYS;SMGS(1)QEDDSGNKPSSYS;S(0.001)MGS(0.999)QEDDSGNKPSSYS ;;; 151.41 0.001962 92268000 11554.54 8984.86 9316.43 9427.01 9969.89 11888.5 10480.36 9942.35 11657.48 9750.69 TRUE FALSE FALSE 10639.98597 9761.471263 9661.705091 9388.00353 9851.005573 9422.691089 10774.4107 12973.72675 10378.68361 10089.52575 1.054557591 0.967485638 0.957597545 0.930470248 0.976359624 0.933908225 1.067880786 1.285860908 1.028659212 1 13.30057074 -4.306106278 3.254939758 1.00191761 1.3123054 0.822719675 0.04181456 0.109842735 1.886107199 0.007083166 0.080090445 4.94E-05 4.306106278 0.31038779 SMGSQEDDSGNKPS(ph)SYS ddPTM_HeLa_Curcumin_4h_R1 1 SMGSQEDDSGNKPSSYS 17 1 H7C3P9;Q9UNS2-2;Q9UNS2 H7C3P9 COPS3 COP9 signalosome complex subunit 3 1 0 SMGSQEDDSGNKPS(0.363)S(0.363)YS(0.273) 93.342 0.0066955 15838000 3315.1 2655.9 3114.9 3366.9 2787.2 3446.3 2803.7 2861.2 3415.1 2809.5 TRUE FALSE FALSE 3052.706337 2885.464162 3230.340934 3352.96866 2753.96446 2731.498532 2882.364276 3733.566709 3040.472074 2907.129916 1.05007565 0.992547373 1.111178732 1.153360447 0.947313859 0.939585987 0.991481069 1.284279278 1.045867286 1 11.50537983 SMGSQEDDSGNKPSS(ph)YS ddPTM_HeLa_Curcumin_4h_R1 1 SMGSQEDDSGNKPSSYS 17 1 H7C3P9;Q9UNS2-2;Q9UNS2 H7C3P9 COPS3 COP9 signalosome complex subunit 3 1 0 SMGSQEDDSGNKPS(0.097)S(0.583)YS(0.32) 145.48 0.0026837 5454700 2837.5 2331.5 2227 2415.8 2207.9 2848 2234.9 1887.6 2525.4 2364.7 TRUE FALSE FALSE 2612.908881 2533.024471 2309.534579 2405.80406 2181.572235 2257.292696 2297.605279 2463.120551 2248.369938 2446.873149 1.067856289 1.035208741 0.943871806 0.983215685 0.891575534 0.92252134 0.938996482 1.006640067 0.918874744 1 11.2567236 -6.761203396 24.99878244 1.03317599 0.9453078 0.168880422 0.049009393 3.541692299 375152.1202 0.00609346 0.008313211 1.73E-07 6.761203396 -0.08786819 SMGSQEDDSGNKPSSYS(ph) ddPTM_HeLa_Curcumin_4h_R1 2 SMGSQEDDSGNKPSSYS 17 1 H7C3P9;Q9UNS2-2;Q9UNS2 H7C3P9 COPS3 COP9 signalosome complex subunit 3 1 0 SMGSQEDDSGNKPS(0.055)S(0.248)Y(0.007)S(0.69);SMGSQEDDSGNKPS(0.13)S(0.201)YS(0.669) ; 192.72 1.52E-06 98160000 5295.3 4377 4512.3 4924.7 4802.7 6411.9 4858.6 4034.9 5298 4903 TRUE FALSE FALSE 4876.171417 4755.328376 4679.529807 4904.322896 4745.430939 5081.999663 4994.91924 5265.122436 4716.822655 5073.378885 0.961128969 0.937309924 0.922369473 0.966677831 0.935359067 1.001699218 0.984535031 1.037794053 0.929720165 1 12.30873119 -4.065685244 1.33546089 0.970167005 1.090695528 0.378685858 0.028318213 1.995464719 2.202934738 0.00447808 0.367243054 8.60E-05 4.065685244 0.120528523 SMGTGDTPGLEVPS(ph)SPLRK ddPTM_HeLa_Curcumin_4h_R1 3 SMGTGDTPGLEVPSSPLRK 19 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 SMGTGDTPGLEVPS(0.5)S(0.5)PLRK;SMGTGDT(0.119)PGLEVPS(0.492)S(0.389)PLRK;SMGTGDTPGLEVPS(0.5)S(0.5)PLRK ;; 226.67 1.18E-24 158949000 9397.1 7918.8 7908.5 8680.6 8477.9 9383.6 6805.5 6199.6 9460.6 7982.2 TRUE FALSE FALSE 8653.309619 8603.265787 8201.595967 8644.681977 8376.80658 7437.335585 6996.444014 8089.829501 8422.795849 8259.580856 1.047669339 1.041610457 0.992979681 1.046624778 1.014192696 0.900449516 0.847070104 0.979447946 1.019760687 1 13.01185286 -5.278413331 5.884979623 1.023760411 0.902355349 0.695074159 0.034628244 0.064211944 8.649747183 0.004850258 0.011452325 5.27E-06 5.278413331 -0.121405063 SMGTGDTPGLEVPSS(ph)PLR ddPTM_HeLa_Curcumin_4h_R1 5 SMGTGDTPGLEVPSSPLR 18 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 SMGTGDTPGLEVPS(0.012)S(0.988)PLR;SMGTGDTPGLEVPS(0.042)S(0.958)PLR;SMGTGDTPGLEVPS(0.049)S(0.951)PLR;SMGTGDTPGLEVPS(0.244)S(0.756)PLR;SMGTGDTPGLEVPS(0.029)S(0.971)PLR ;;;; 245.67 3.18E-32 229225000 18333.9 15941.2 15749.3 16914.5 17800.7 20392.6 16012.1 17071.4 19511.3 16540.6 TRUE FALSE FALSE 16882.75247 17319.0863 16332.98291 16844.51228 17588.43828 16162.94489 16461.35643 22276.39127 17370.9592 17115.38462 0.986408009 1.011901671 0.954286642 0.984173751 1.02763909 0.944351836 0.961787117 1.301541962 1.014932448 1 14.06300609 -4.258424577 24.98308873 0.988835289 1.301542077 0.929160335 0.026029063 46.73762689 387285.8687 0.003293813 0.031040069 5.52E-05 4.258424577 0.312706787 SMGTGDTPGLEVPSS(ph)PLRK ddPTM_HeLa_Curcumin_4h_R1 2 SMGTGDTPGLEVPSSPLRK 19 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 SMGTGDTPGLEVPS(0.359)S(0.641)PLRK;SMGTGDTPGLEVPS(0.226)S(0.774)PLRK ; 247.02 1.25E-33 159285000 7792.6 6501.8 7159.5 8060.1 7509.8 8951.3 6403.9 7361.2 8823.1 7681.4 TRUE FALSE FALSE 7175.807487 7063.786621 7424.837368 8026.749442 7420.25054 7094.699478 6583.576199 9605.595993 7855.228004 7948.328078 0.902807159 0.888713519 0.934138261 1.009866397 0.93356118 0.892602747 0.828296987 1.208505223 0.988286836 1 12.95643571 -4.246159517 25 0.939515805 1.208505417 0.699190312 0.054359357 1419.051957 2321732.013 0.008232071 0.268197043 5.67E-05 4.246159517 0.268989612 SMIEISR ddPTM_HeLa_Curcumin_4h_R1 1 SMIEISR 7 0 P49368;B4DUR8;P49368-2;Q5SZX9;E9PRC8;Q5SZX6;E9PM09;Q5SZW8 P49368 CCT3 T-complex protein 1 subunit gamma 0 0 102.77 0.018908 2547000 5870.8 4971.4 4747.3 5465.1 5618.9 5870.8 4998.8 4828.9 5945.2 5332.4 FALSE FALSE TRUE 5406.119985 5401.105664 4923.239114 5442.486864 5551.898287 4653.129902 5139.052874 6301.20938 5293.026434 5517.700503 0.979777714 0.978868944 0.892262839 0.986368662 1.006197833 0.843309618 0.931375828 1.141999167 0.959281213 1 12.42985144 -7.691040697 1.39279039 0.993838392 0.962101799 0 0.075085462 1.153178024 4.625576518 0.015613904 0.015384393 2.04E-08 7.691040697 -0.031736594 SMIIDRR ddPTM_HeLa_Curcumin_4h_R1 2 SMIIDRR 7 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 148.33 0.0043096 28854000 8769.1 5992.9 7485.4 6899.6 7269.9 7967.7 7115.1 6634.3 7003.7 8003.1 FALSE FALSE TRUE 8075.016482 6510.899572 7762.815509 6871.051283 7183.211191 6315.109206 7314.730557 8657.067529 6235.411632 8281.207129 0.975101378 0.786225905 0.937401443 0.829716148 0.867411125 0.762583173 0.883292791 1.045387151 0.752959265 1 13.01562537 -7.406633684 7.433270343 0.989079767 0.869968113 0 0.105621435 0.209746933 12.22778516 0.012316238 0.014038788 3.92E-08 7.406633684 -0.119111655 SMMDNIR ddPTM_HeLa_Curcumin_4h_R1 1 SMMDNIR 7 0 P0DKX4 P0DKX4 SMIM18 Small integral membrane protein 18 0 0 68.915 0.0082984 0 2094.3 2078.7 2134.1 1941.2 1907.7 2694 1974.8 1794 1966.7 1874.5 FALSE FALSE TRUE 1928.533945 2258.373565 2213.191623 1933.167829 1884.951923 2135.234032 2030.207573 2340.982341 1750.95793 1939.638735 0.994274815 1.164326905 1.141032906 0.99666386 0.971805671 1.100841096 1.046693663 1.206916679 0.902723738 1 10.92157226 -1 0.198290353 0.989460614 1.678121495 0.296692133 0.077212243 56.80853836 0.648962781 0.073293741 12.21626202 0.1 1 0.688660881 SMMS(ph)PMADR ddPTM_HeLa_Curcumin_4h_R1 2 SMMSPMADR 9 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 0 SMMS(1)PMADR;S(0.002)MMS(0.998)PMADR ; 105.4 0.010637 18450600 1987.74 1550.53 1404.07 1751.07 1740.44 2611.9 2479.5 1584.25 1938.54 1584.24 TRUE FALSE FALSE 1830.408282 1684.550904 1456.106069 1743.824536 1719.68639 2070.162498 2549.068097 2067.280532 1725.887012 1639.292222 1.116584497 1.027608673 0.888252899 1.063766736 1.049041999 1.262839212 1.554980901 1.261081157 1.052824499 1 10.67885734 -5.110625893 3.28748142 1.041354264 1.410022498 0.756867776 0.087969217 0.088807971 1.791240319 0.012591014 0.036711894 7.75E-06 5.110625893 0.368668234 SMMS(ph)PMAER ddPTM_HeLa_Curcumin_4h_R1 3 SMMSPMAER 9 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;H7C1M2 P18583-10 SON Protein SON 1 0 SMMS(1)PMAER;S(0.143)MMS(0.857)PMAER;SMMS(1)PMAER ;; 133.75 0.0033291 54645000 4523.12 4173.39 4545.83 4711.24 4936 7429.6 5750.8 3754.98 5323.5 3580.08 TRUE FALSE FALSE 4165.110279 4534.119235 4714.302459 4691.746137 4877.141424 5888.617211 5912.151971 4899.856116 4739.525369 3704.487514 1.124341832 1.22395317 1.272592347 1.266503429 1.316549565 1.589590244 1.595943285 1.322681234 1.279401092 1 11.85505826 -6.375100709 0.45849225 1.017381715 1.548954131 0.518058377 0.120475215 0.359980791 0.149672229 0.029706098 0.078876124 4.22E-07 6.375100709 0.531572415 SMPEQTGEK ddPTM_HeLa_Curcumin_4h_R1 2 SMPEQTGEK 9 0 P62888;A0A0C4DH44;A0A0B4J213 P62888 RPL30 60S ribosomal protein L30 0 0 ; ; 157.99 3.96E-08 10136800 6392 5325.2 5487.1 5607.1 5608.2 6628.5 5116.9 4666.6 6187.2 5505.4 FALSE FALSE TRUE 5886.066455 5785.486559 5690.456753 5583.899306 5541.325878 5253.674381 5260.466443 6089.424858 5508.47964 5696.71224 1.03323921 1.01558343 0.998901913 0.980196835 0.972723502 0.922229202 0.923421479 1.068936713 0.966957678 1 12.47591382 -6.279218375 1.872611592 1.016032252 0.965429646 0.077556705 0.041703168 0.354598196 2.425554646 0.006099955 0.010704929 5.26E-07 6.279218375 -0.050602606 SMQQLDPS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 1 SMQQLDPSPAR 11 0 Q9H410-4;Q9H410;Q5JW54;Q9H410-3;Q9H410-2 Q9H410-4 DSN1 Kinetochore-associated protein DSN1 homolog 1 0 SMQQLDPS(1)PAR 125.84 0.0034389 15913000 4845.4 4583.2 4514.3 4515.2 4590.6 5934.5 4058 2483 4795.8 4274.1 TRUE FALSE FALSE 4461.881477 4979.351386 4681.603929 4496.517299 4535.860093 4703.617804 4171.856558 3240.05527 4269.712739 4422.624657 1.008876363 1.125881523 1.058557823 1.016707871 1.025603673 1.063535382 0.943298806 0.732609145 0.965425074 1 12.11068709 -4.3153097 2.788238015 1.022331585 0.696769381 0.818143108 0.042619014 0.116722443 1.319146055 0.00602182 0.081091231 4.84E-05 4.3153097 -0.325562203 SMS(ph)AAFCSLLAPER ddPTM_HeLa_Curcumin_4h_R1 2 SMSAAFCSLLAPER 14 0 E9PNR2;Q13671-2;Q13671 E9PNR2 RIN1 Ras and Rab interactor 1 1 0 S(0.142)MS(0.858)AAFCSLLAPER;S(0.005)MS(0.995)AAFCSLLAPER ; 169.3 0.00020549 76029000 2111.82 1610.66 2311.74 2116.6 1926.8 2878.91 1825.53 1297.39 1874.98 2158.91 TRUE FALSE FALSE 1944.667219 1749.878273 2397.415118 2107.84207 1903.824168 2281.791614 1876.749459 1692.958239 1669.299385 2233.931962 0.870513181 0.783317623 1.073181797 0.943556969 0.852230149 1.021423952 0.840110393 0.75783787 0.747247192 1 11.12536953 SMS(ph)AEDLLER ddPTM_HeLa_Curcumin_4h_R1 3 SMSAEDLLER 10 0 A0A2R8Y5P9;Q8TF72 A0A2R8Y5P9 SHROOM3 Protein Shroom3 1 0 S(0.025)MS(0.975)AEDLLER;S(0.306)MS(0.694)AEDLLER;S(0.042)MS(0.958)AEDLLER ;; 158.06 0.00062588 11054100 9735.5 7136.9 7745.2 8446.5 8606.2 9388.5 6417.4 3540.48 9479 7264.4 TRUE FALSE FALSE 8964.924902 7753.781835 8032.243925 8411.550621 8503.576686 7441.21927 6597.454972 4619.956054 8439.177415 7516.837359 1.192645853 1.031521831 1.068566944 1.119027886 1.131270544 0.989940172 0.877690265 0.614614343 1.122703208 1 12.87591007 -4.337830163 1.348030707 1.091096199 0.456630842 0.884883091 0.053716642 0.366635139 0.637387241 0.010979982 0.303954218 4.59E-05 4.337830163 -0.634465357 SSS(ph)LVDIREEETEGGSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSLVDIREEETEGGSR 17 1 Q96Q42-3;Q96Q42 Q96Q42-3 ALS2 Alsin 1 0 S(0.197)S(0.197)S(0.605)LVDIREEETEGGSR 56.553 0.01799 9469800 3898.2 3082.2 3392.9 3197.8 2789.3 3717.3 2608.7 786.89 3536.1 3230.3 TRUE FALSE FALSE 3589.653357 3348.611634 3518.643859 3184.568351 2756.039419 2946.290077 2681.893101 1026.809139 3148.198677 3342.552685 1.073925737 1.001812671 1.052681645 0.952735425 0.824531333 0.881449107 0.80234879 0.307193105 0.941854617 1 11.70673458 -4.190287204 0.865244398 1.025592952 3.43E-32 0.863783634 0.077668042 0.604688141 0.305979713 0.011777162 0.604792411 6.45E-05 4.190287204 -1.025592952 down S(ph)YSAGNASQLEQLSR ddPTM_HeLa_Curcumin_4h_R1 2 SYSAGNASQLEQLSR 15 0 Q14678-2;Q14678 Q14678-2 KANK1 KN motif and ankyrin repeat domain-containing protein 1 1 0 S(0.962)YS(0.033)AGNAS(0.004)QLEQLSR;S(0.984)YS(0.011)AGNAS(0.005)QLEQLSR ; 208.85 8.91E-10 146811000 2665.21 2141.19 2386.86 2539.82 2550.37 2803.24 2043.43 632.78 2934.1 2734.21 TRUE FALSE FALSE 2454.255816 2326.264923 2475.319131 2529.310898 2519.958503 2221.816425 2100.763146 825.711709 2612.236571 2829.223594 0.867466192 0.822227316 0.874911102 0.8939947 0.89068906 0.785309592 0.742522843 0.291850991 0.923305099 1 11.46619048 -4.188711148 1.294491997 0.915526405 8.11E-27 0.911931416 0.055025783 0.40671804 0.513129204 0.01045133 0.512630913 6.48E-05 4.188711148 -0.915526405 down SMS(ph)FPT(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 SMSFPTGK 8 0 Q01780-2;Q01780 Q01780-2 EXOSC10 Exosome component 10 2 0 SMS(1)FPT(1)GK 64.803 0.0096431 0 359.81 198.36 349.73 360.29 305.51 506.28 379.38 370.28 433.44 415.91 TRUE FALSE FALSE 331.3306588 215.5053545 362.6913015 358.7992154 301.8669928 401.271821 390.0243818 483.1766674 385.8927164 430.3628415 0.769886772 0.500752699 0.84275701 0.833713278 0.701424388 0.932403503 0.90626872 1.122719298 0.896668297 1 8.749409708 -4.109080531 1.502389231 0.841342725 1.312008587 0.323954125 0.132525489 1.970600804 3.051809824 0.022655506 1.524903992 7.78E-05 4.109080531 0.470665863 GPSPAPASS(ph)PKR ddPTM_HeLa_Curcumin_4h_R1 1 GPSPAPASSPKR 12 1 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 1 0 GPSPAPAS(0.123)S(0.877)PKR 118.52 0.0017421 16278000 2155.9 1938.5 1919.3 1879.2 2379.1 2769.1 3169 5182.7 2092.6 1697.2 TRUE FALSE FALSE 1985.25824 2106.055302 1990.430946 1871.424368 2350.730786 2194.757446 3257.913611 6762.881372 1863.047015 1756.177574 1.130442769 1.199226851 1.133388204 1.065623657 1.338549599 1.249735493 1.855116282 3.850909767 1.060853437 1 10.77822301 -3.951046642 1.339542398 1.091454027 7.106880144 0.98749137 0.091773198 0.213574434 0.192518629 0.015086578 2.126680462 0.000111932 3.951046642 6.015426118 up SMSQVDVDS(ph)GIENMEVDENDRR ddPTM_HeLa_Curcumin_4h_R1 2 SMSQVDVDSGIENMEVDENDRR 22 1 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 0 SMSQVDVDS(1)GIENMEVDENDRR;SMSQVDVDS(1)GIENMEVDENDRR ; 101.71 3.68E-05 6278100 5279.7 4287.3 4316.3 5197.4 4432.9 5104.8 3795.7 3937 5036.4 4993.2 TRUE FALSE FALSE 4861.806174 4657.875108 4476.265875 5175.894536 4380.040563 4046.006937 3902.197126 5137.373176 4483.91952 5166.713328 0.940986245 0.901516073 0.866366216 1.001776992 0.84774213 0.783091045 0.755257139 0.994321312 0.867847553 1 12.33503112 -7.029857498 0.389960758 0.999262339 0.834223163 0.022057717 0.082904873 0.921609306 0.364450897 0.039201234 0.056600975 9.34E-08 7.029857498 -0.165039176 SMSSIPPY(ph)PASSLASSSPPGSGR ddPTM_HeLa_Curcumin_4h_R1 1 SMSSIPPYPASSLASSSPPGSGR 23 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 0 SMSSIPPY(0.8)PAS(0.093)S(0.093)LAS(0.007)S(0.001)S(0.005)PPGSGR 142.39 7.95E-05 23205000 4992.8 4102.3 4145.4 4535.4 4322.8 5699.6 3571.4 2489.1 4957.6 4255.4 TRUE FALSE FALSE 4597.614612 4456.884533 4299.032171 4516.633717 4271.253433 4517.438712 3671.603872 3248.015132 4413.763683 4403.274833 1.044135282 1.012174961 0.976326106 1.025744222 0.970017452 1.025927039 0.833834819 0.737636249 1.002382057 1 12.10436118 -4.621954497 2.943787546 1.014961821 0.746753642 0.932473416 0.024309878 0.046824266 0.764175534 0.003750597 0.020035671 2.39E-05 4.621954497 -0.268208179 SMSSIPPYPASSLASSS(ph)PPGSGR ddPTM_HeLa_Curcumin_4h_R1 1 SMSSIPPYPASSLASSSPPGSGR 23 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YDW2 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 0 SMSSIPPYPASSLAS(0.045)S(0.223)S(0.732)PPGSGR 210.71 2.14E-18 23769000 7538.3 5900.3 5743 6273.8 6395.2 8314.9 5389.4 4075.1 7196.3 6408 TRUE FALSE FALSE 6941.635601 6410.295641 5955.840632 6247.840678 6318.941417 6590.296012 5540.612059 5317.579231 6406.883894 6630.677523 1.046896878 0.966763294 0.898225047 0.942262786 0.952985784 0.993909897 0.835602703 0.801966196 0.966248754 1 12.69494058 -2.266692855 0.335307365 1.020480615 2.47E-14 0.572397276 0.046793501 10.34682756 0.284923474 0.015889684 5.701584108 0.005411369 2.266692855 -1.020480615 SMVEEGTGLR ddPTM_HeLa_Curcumin_4h_R1 1 SMVEEGTGLR 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 92.051 0.018861 3421600 2303.4 1724.1 2228.2 2513.5 1989.8 3327.2 2119.5 1989.4 2446.3 2101.1 FALSE FALSE TRUE 2121.083459 1873.123522 2310.779052 2503.099803 1966.072935 2637.101215 2178.967466 2595.958902 2177.94701 2174.113069 0.975608624 0.861557547 1.062860569 1.151319975 0.904310343 1.212954953 1.002232817 1.19403123 1.001763451 1 11.08621126 -6.545178316 24.99676972 0.977858224 1.086411353 0.308645018 0.093084843 230.562097 258448.2776 0.01320688 0.018678126 2.85E-07 6.545178316 0.108553128 SNAEDTLR ddPTM_HeLa_Curcumin_4h_R1 1 SNAEDTLR 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 143.37 0.00049685 3273100 4154.1 3173.3 3747.7 3355.4 3707.9 4876.5 3685.5 3233.1 4305.1 4098.4 FALSE FALSE TRUE 3825.298602 3447.585912 3886.593059 3341.516244 3663.685714 3865.058931 3788.905211 4218.857307 3832.841301 4240.819095 0.902018812 0.812952836 0.91647226 0.787941237 0.863909927 0.911394437 0.893437123 0.994821333 0.903797407 1 12.05012723 -8.679068967 0.848044507 0.993621669 0.881885554 0.090968345 0.060954869 0.423109076 0.609465957 0.025269537 0.011331003 2.09E-09 8.679068967 -0.111736114 SNATNSSYS(ph)PTTGR ddPTM_HeLa_Curcumin_4h_R1 2 SNATNSSYSPTTGR 14 0 Q13009-2;Q13009 Q13009-2 TIAM1 T-lymphoma invasion and metastasis-inducing protein 1 1 0 SNATNS(0.11)S(0.36)YS(0.522)PT(0.005)T(0.003)GR;SNATNS(0.001)S(0.001)YS(0.949)PT(0.044)T(0.004)GR ; 139 0.00015167 4412300 2726.7 2410.2 2045.22 2372.7 2082.8 2583.8 1987.47 1846.33 2335.2 2516.1 TRUE FALSE FALSE 2510.878818 2618.526948 2121.017652 2362.882396 2057.96397 2047.890755 2043.233059 2409.267518 2079.034402 2603.534288 0.964411658 1.00575858 0.814668607 0.907567228 0.790450112 0.786581058 0.784792069 0.925383441 0.798543124 1 11.34625569 -6.760461757 24.9999743 0.984417145 0.831714442 0.26578598 0.075104747 10.14265832 259365.4667 0.00731344 0.010008828 1.74E-07 6.760461757 -0.152702702 SNDRNS(ph)MDIQCEVDALLER ddPTM_HeLa_Curcumin_4h_R1 3 SNDRNSMDIQCEVDALLER 19 1 Q02241-2;A0A2U3TZL8;H7BYN4;Q02241;A0A2R8Y531;H0YME6 Q02241-2 KIF23 Kinesin-like protein KIF23;Kinesin-like protein 1 0 S(0.009)NDRNS(0.991)MDIQCEVDALLER;S(0.177)NDRNS(0.823)MDIQCEVDALLER;S(0.182)NDRNS(0.818)MDIQCEVDALLER ;; 93.115 0.0018236 59538300 6416.11 4994.99 5859.97 6260.1 6145.87 7614.35 4256.22 2646.87 7787.05 5909.87 TRUE FALSE FALSE 5908.268123 5426.734678 6077.145643 6234.197365 6072.584514 6035.047979 4375.638078 3453.888478 6932.830097 6115.237543 0.96615513 0.887411918 0.993770986 1.019453017 0.993025123 0.986886926 0.715530353 0.564800378 1.133697595 1 12.57819283 -4.619627183 2.922898638 0.981546296 0.579989224 0.855018058 0.059963444 0.045245947 0.727345195 0.005374096 0.028990662 2.40E-05 4.619627183 -0.401557073 SNEDS(ph)LILEK ddPTM_HeLa_Curcumin_4h_R1 4 SNEDSLILEK 10 0 A0A0U1RRH6;O94880 A0A0U1RRH6 PHF14 PHD finger protein 14 1 0 SNEDS(1)LILEK;S(0.001)NEDS(0.999)LILEK;S(0.006)NEDS(0.994)LILEK;S(0.056)NEDS(0.944)LILEK ;;; 145.61 0.0011192 50686700 11382.7 10230 9986.4 10644.7 10892.4 14406.8 13437.2 8257.6 12396.8 10985.4 TRUE FALSE FALSE 10481.74728 11114.23562 10356.50477 10600.65505 10762.51524 11418.66728 13814.21167 10775.30423 11036.90206 11367.14183 0.922109308 0.977751116 0.911091365 0.932569964 0.946809269 1.004532841 1.215275737 0.947934352 0.970947862 1 13.47258193 -4.990083431 24.96834658 0.956951611 1.088679893 0.385053592 0.065063026 140.9854866 354972.9338 0.008411465 0.025193952 1.02E-05 4.990083431 0.131728281 SNEDVNSS(ph)ELDEEYLIELEK ddPTM_HeLa_Curcumin_4h_R1 1 SNEDVNSSELDEEYLIELEK 20 0 Q99614 Q99614 TTC1 Tetratricopeptide repeat protein 1 1 0 S(0.001)NEDVNS(0.248)S(0.751)ELDEEYLIELEK 164.27 2.22E-06 2070800 1706.6 1450.1 1503.8 1916.6 1622.8 2725.8 1806.5 1224.1 1579.7 1253.1 TRUE FALSE FALSE 1571.520809 1575.440182 1559.532151 1908.669617 1603.44917 2160.438354 1857.185528 1597.322455 1406.410862 1296.645132 1.211989904 1.215012607 1.202743999 1.472006157 1.236613728 1.666175502 1.432300544 1.231888676 1.08465364 1 10.34056798 -7.408121555 0.363499774 0.992032262 1.456486185 0.528548083 0.127451563 0.584903728 0.226236591 0.091500006 0.092169574 3.91E-08 7.408121555 0.464453923 SNEEGS(ph)EEKGPEVR ddPTM_HeLa_Curcumin_4h_R1 1 SNEEGSEEKGPEVR 14 1 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 1 0 SNEEGS(1)EEKGPEVR 130.87 0.01016 6635800 1804.1 1717.4 1589.7 1803.9 1781.3 1916.5 1668.4 1867.8 1845.4 1696.7 TRUE FALSE FALSE 1661.303581 1865.844403 1648.61568 1796.43594 1760.059161 1518.996297 1715.210814 2437.283622 1642.964237 1755.660199 0.946255763 1.062759414 0.939028909 1.023225304 1.002505589 0.865199483 0.976960584 1.388243365 0.935809924 1 10.77779793 -4.261532697 10.03512457 0.975539696 1.38922237 0.851379593 0.052106487 0.018577683 62.74159646 0.006754639 0.052253445 5.48E-05 4.261532697 0.413682674 SNEEGSEEK(ac)GPEVR ddPTM_HeLa_Curcumin_4h_R1 2 SNEEGSEEKGPEVR 14 1 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 1 ; SNEEGSEEK(1)GPEVR;SNEEGSEEK(1)GPEVR 271.04 2.92E-77 5413600 776.8 984.16 679.24 732.71 2055.73 2294.2 1709.41 1790.18 2287.25 800.5 FALSE TRUE FALSE 715.3154603 1069.226405 704.4132319 729.6782402 2031.216762 1818.357059 1757.371444 2335.997641 2036.344397 828.3173154 0.863576611 1.290841547 0.850414713 0.880916319 2.452220574 2.195242119 2.121616211 2.820172412 2.458410997 1 9.694039737 -5.761852871 24.99999928 0.953169795 2.363186776 0.513460934 0.520489923 2.067548803 125018.3955 0.02933364 0.055642283 1.73E-06 5.761852871 1.410016981 SNEEGSEEKGPEVR ddPTM_HeLa_Curcumin_4h_R1 2 SNEEGSEEKGPEVR 14 1 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 0 ; ; 128.35 0.00043949 11860700 7698.4 7014.6 7105.3 7428.5 7269.3 9489.2 7618.3 7603.8 8520.8 7346.4 FALSE FALSE TRUE 7089.063517 7620.910768 7368.628668 7397.762835 7182.618345 7521.032955 7832.048994 9922.163616 7586.089558 7601.686853 0.932564529 1.002528901 0.969341254 0.973173847 0.944871643 0.98939 1.030304082 1.305258137 0.99794818 1 12.89210388 -4.190257814 2.158404083 0.969633325 1.437176156 0.948891922 0.022759943 0.148862024 0.657818723 0.003835251 0.142746504 6.45E-05 4.190257814 0.467542831 SNEQNGLLVS(ph)WGETLS(ph)S(ph)LK ddPTM_HeLa_Curcumin_4h_R1 1 SNEQNGLLVSWGETLSSLK 19 0 Q6ZN30-2 Q6ZN30-2 3 0 S(0.467)NEQNGLLVS(0.527)WGET(0.033)LS(0.981)S(0.993)LK 49.266 0.016422 2205600 269.3 338.6 381.04 353.31 325.48 466.06 359.94 307.64 517.89 336.04 TRUE FALSE FALSE 247.9846208 367.8670752 395.1616776 351.8480968 321.5988636 369.3939024 370.0389477 401.4380198 461.0787627 347.717365 0.713178707 1.05794853 1.136445048 1.011879567 0.92488583 1.062339531 1.064194616 1.154495174 1.326015923 1 8.441771307 -7.223316117 23.79724176 0.864556611 1.055242741 0 0.170194259 254.7715971 159033.0823 0.020041993 0.024545932 5.98E-08 7.223316117 0.19068613 SNES(ph)VDIQDQEEK ddPTM_HeLa_Curcumin_4h_R1 2 SNESVDIQDQEEK 13 0 Q5UIP0-2;Q5UIP0 Q5UIP0-2 RIF1 Telomere-associated protein RIF1 1 0 SNES(1)VDIQDQEEK;S(0.002)NES(0.998)VDIQDQEEK ; 185.86 6.26E-21 14948000 4505.9 2572.1 3416.3 3553.3 3834.8 10934.1 15898.5 5116.1 3842.2 3171.9 TRUE FALSE FALSE 4149.25326 2794.420863 3542.911083 3538.597386 3789.072515 8666.244407 16344.56912 6675.975338 3420.720273 3282.123289 1.264197867 0.851406427 1.079457038 1.078142737 1.154457703 2.640438413 4.979876648 2.03404161 1.042227842 1 11.68041372 -5.130075795 3.593358627 1.100113297 3.564128256 0.687210976 0.677027136 0.083836008 1.950421922 0.082903735 0.233267228 7.41E-06 5.130075795 2.464014958 SNETQNPHKPS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 SNETQNPHKPSPSR 14 1 A0A5S6SZ32;Q96LW4-2;Q96LW4 A0A5S6SZ32 PRIMPOL DNA-directed primase/polymerase protein 1 0 SNETQNPHKPS(0.849)PS(0.151)R 58.98 0.019617 1006900 718.95 585.7 682.49 635.33 674.4 663.59 394.22 252.3 791.6 597.6 TRUE FALSE FALSE 662.0443489 636.3252982 707.7836798 632.7011728 666.3582205 525.9539538 405.2807522 329.2251086 704.7634605 618.3665555 1.070634146 1.029042228 1.144602135 1.023181424 1.077610383 0.850553687 0.655405356 0.532410923 1.139717946 1 9.272318483 -4.841706702 1.870564186 1.044716278 0.540291576 0.930859315 0.051914768 0.061089361 0.394019283 0.00669126 0.036109125 1.44E-05 4.841706702 -0.504424701 SNGDLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SNGDLSPK 8 0 P49006 P49006 MARCKSL1 MARCKS-related protein 1 0 SNGDLS(1)PK 100.69 0.014651 20228000 7437.9 9842.9 7464.2 6841.4 7289.8 9747.5 7788.8 5255 6687 7026 TRUE FALSE FALSE 6849.182367 10693.67642 7740.829818 6813.0921 7202.873896 7725.758623 8007.332766 6857.225309 5953.45283 7270.152977 0.942096045 1.470901156 1.064740982 0.937131876 0.990745851 1.062667959 1.101398112 0.943202341 0.818889623 1 12.82777001 SNGELSES(ph)PGAGK ddPTM_HeLa_Curcumin_4h_R1 2 SNGELSESPGAGK 13 0 E7ETD6;E9PE19;A0A2R8Y7Q1;Q12830-4;Q12830;A0A0A0MR81;F5GXF5;Q12830-2;F5H176 E7ETD6 BPTF Nucleosome-remodeling factor subunit BPTF 1 0 SNGELS(0.001)ES(0.999)PGAGK;SNGELS(0.091)ES(0.909)PGAGK ; 190.18 8.24E-06 209350000 9113.7 7685.6 8846.7 9960.5 9009.3 9967.7 7946.2 3806.2 9015.4 7691.8 TRUE FALSE FALSE 8392.341028 8349.909018 9174.566484 9919.28609 8901.869982 7900.286661 8169.148986 4966.692858 8026.433175 7959.089477 1.054434813 1.049103549 1.152715585 1.246284028 1.118453311 0.992611866 1.026392404 0.62402777 1.008461231 1 12.95838768 -4.227112196 3.167824074 1.056984214 0.540039433 0.752688709 0.076742315 0.186779814 2.660789117 0.01213952 0.247354229 5.93E-05 4.227112196 -0.516944781 SNITSLS(ph) ddPTM_HeLa_Curcumin_4h_R1 1 SNITSLS 7 0 Q14195-2;Q14195;H0YBT4;Q5T0Q6;O14531 Q14195-2 DPYSL3;DPYSL4 Dihydropyrimidinase-related protein 3;Dihydropyrimidinase-related protein 4 1 0 SNITSLS(1) 98.523 0.012386 17329000 10980 9116.8 9090.3 10353 9227.2 12603 9227.4 8187.9 10954 9185.5 TRUE FALSE FALSE 10110.92141 9904.815568 9427.194515 10310.16203 9117.171666 9988.995735 9486.29601 10684.35302 9752.373606 9504.695441 1.063781736 1.042097101 0.991846038 1.084744071 0.959228175 1.050953794 0.998064175 1.124113138 1.026058506 1 13.21442468 -4.250334707 24.76335275 1.027629008 1.124113202 0.407634648 0.035946523 1167.875175 2604299.033 0.004940766 0.100121713 5.62E-05 4.250334707 0.096484193 SNNSETSSVAQS(ph)GSESKVEPK ddPTM_HeLa_Curcumin_4h_R1 1 SNNSETSSVAQSGSESKVEPK 21 1 P49792;J3KNE0;J3KQ37;A6NKT7;Q99666;O14715;Q7Z3J3;H7BZ48 P49792 RANBP2;RGPD3;RGPD8;RGPD5;RGPD4;RGPD6 E3 SUMO-protein ligase RanBP2;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8;RanBP2-like and GRIP domain-containing protein 4 1 0 SNNSETSSVAQS(0.58)GS(0.402)ES(0.017)KVEPK 70.555 0.0013494 8352700 1044.6 1106.2 966.83 949.79 1182.8 1569.8 1781.8 898.64 1069.2 981.57 TRUE FALSE FALSE 961.9188077 1201.814999 1002.66157 945.8600206 1168.695883 1244.205785 1831.792513 1172.631199 951.911435 1015.679484 0.94706925 1.18326206 0.987183049 0.93125837 1.150654218 1.224998441 1.803514338 1.154528783 0.937216366 1 9.988229491 -5.195138294 2.324956537 0.992967293 1.478230783 0.530341394 0.169800436 0.142794168 1.488820089 0.021716987 0.067283121 6.38E-06 5.195138294 0.48526349 SNNVEMDWVLK ddPTM_HeLa_Curcumin_4h_R1 1 SNNVEMDWVLK 11 0 P31943;G8JLB6;E9PCY7;D6RBM0;D6RIH9;D6RAM1;E5RGV0;D6R9T0;D6RFM3;D6RIT2;D6RIU0;D6RDU3;D6RJ04;H0YAQ2;E5RGH4;E7EQJ0 P31943;E7EQJ0 HNRNPH1 "Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed" 0 0 125.82 0.018009 25322000 974.2 666.66 496.14 630.02 660.7 964.8 800.14 586.02 822.65 778.76 FALSE FALSE TRUE 897.091042 724.2831198 514.5273848 627.4131442 652.821584 764.6896045 822.5897749 764.6948003 732.4073532 805.821852 1.113262242 0.898812955 0.638512574 0.77860031 0.810131399 0.948956153 1.020808474 0.948962601 0.908894877 1 9.654317118 -7.145443319 5.635886226 1.053111305 0.856567382 0.230254142 0.11293388 0.181342292 7.820325289 0.01957621 0.024060883 7.15E-08 7.145443319 -0.196543923 SNNWS(ph)LEDVTASDK ddPTM_HeLa_Curcumin_4h_R1 4 SNNWSLEDVTASDK 14 0 Q14680-3;Q14680-4;Q14680-5;Q14680-2;Q14680-8;Q14680-6;Q14680 Q14680-3 MELK Maternal embryonic leucine zipper kinase 1 0 S(0.019)NNWS(0.981)LEDVTASDK;S(0.296)NNWS(0.461)LEDVT(0.242)AS(0.001)DK;SNNWS(0.926)LEDVT(0.014)AS(0.06)DK;S(0.086)NNWS(0.792)LEDVT(0.119)AS(0.003)DK ;;; 205.12 4.35E-09 41632000 7849.1 6343.2 7311.8 7514.4 7431.6 7361.6 5642.3 2408.49 7540.8 6025.8 TRUE FALSE FALSE 7227.835453 6891.477943 7582.78174 7483.307404 7342.983024 5834.721178 5800.607753 3142.827514 6713.593106 6235.196101 1.15919938 1.105254403 1.216125622 1.20017194 1.177666733 0.93577188 0.930300773 0.504046298 1.076725254 1 12.60621922 -4.050404365 1.245511177 1.102701744 3.64E-16 0.855224585 0.076694633 0.754212502 0.699301588 0.01394053 1.203278433 8.90E-05 4.050404365 -1.102701744 SNPKS(ph)PQKPIVR ddPTM_HeLa_Curcumin_4h_R1 1 SNPKSPQKPIVR 12 2 H7C560;A0A2U3TZI2;A0A2R8Y8E0;P15056;A0A2R8YDP5;A0A2R8YES9;H7C5K3;A0A2R8Y467 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 0 S(0.003)NPKS(0.997)PQKPIVR 77.744 0.019531 18657000 4188.5 3782.7 3423.6 3705.1 3670.2 2947.8 2393.8 3558.8 4349.4 3893 TRUE FALSE FALSE 3856.975805 4109.659733 3550.481628 3689.769278 3626.435262 2336.393051 2460.963585 4643.861737 3872.281702 4028.28146 0.957474259 1.020201734 0.881388667 0.915966105 0.900243763 0.579997469 0.610921459 1.152814614 0.961273868 1 11.97594877 -5.490775449 9.364614084 0.968165181 0.760031168 0.208849626 0.149354076 0.410208168 115.207113 0.02004169 0.044203979 3.23E-06 5.490775449 -0.208134013 SNPS(ph)AVAGNETPGASTK ddPTM_HeLa_Curcumin_4h_R1 1 SNPSAVAGNETPGASTK 17 0 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;A0A3B3IRI3;A0A3B3ISZ5;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 S(0.001)NPS(0.962)AVAGNET(0.036)PGAS(0.001)TK 214.63 2.03E-15 9475500 2916.8 2672.4 2449.9 3041.2 3060.4 5095.1 5272.9 1726.8 2825.6 2135.5 TRUE FALSE FALSE 2685.932202 2903.390348 2540.695449 3028.61632 3023.906729 4038.318826 5420.843383 2253.293371 2515.638749 2209.708466 1.215514283 1.313924616 1.149787625 1.370595428 1.36846411 1.827534667 2.453193924 1.019724278 1.138448256 1 11.10964033 -5.579888565 1.725559992 1.131814696 1.828506438 0.347040411 0.33985512 0.242798678 1.437937265 0.048204722 0.12654331 2.63E-06 5.579888565 0.696691743 SNPSAVAGNET(ph)PGASTK ddPTM_HeLa_Curcumin_4h_R1 1 SNPSAVAGNETPGASTK 17 0 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;A0A3B3IRI3;A0A3B3ISZ5;A0A3B3IS03 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 SNPS(0.033)AVAGNET(0.966)PGASTK 231.4 8.61E-22 23357000 2459 2126.2 1879.2 2222.6 2210.4 3602.4 3491.6 1410.7 2187.5 1473.4 TRUE FALSE FALSE 2264.367555 2309.979254 1948.844805 2213.40347 2184.042424 2855.221633 3589.564899 1840.815936 1947.536723 1524.60054 1.485220224 1.515137371 1.27826585 1.451792395 1.432534205 1.872767034 2.35442977 1.207408687 1.277407866 1 10.57421558 -9.580060383 0.096470913 3.13E-13 2.302472983 0.282424427 0.306491393 28.90320981 0.644146803 11.6980445 4.587537753 2.63E-10 9.580060383 2.302472983 SNPTPMEPT(ph)SPGEHQQNSK ddPTM_HeLa_Curcumin_4h_R1 1 SNPTPMEPTSPGEHQQNSK 19 0 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312 E7EUR8 FAM193A Protein FAM193A 1 0 SNPT(0.003)PMEPT(0.498)S(0.498)PGEHQQNSK 73.21 0.0096 3428300 1847.7 1408.4 1441.8 1724.8 1605.4 2477.3 1893.1 1725.1 1882.6 1704.4 TRUE FALSE FALSE 1701.452595 1530.13582 1495.234376 1717.663235 1586.256654 1963.480055 1946.215291 2251.075049 1676.08349 1763.627773 0.964745861 0.867607011 0.847817436 0.973937506 0.899428257 1.113318856 1.103529509 1.276388977 0.950361247 1 10.78433039 -4.608311665 1.305333911 0.958788457 1.297967767 0.757898602 0.06128546 0.338895471 0.750997006 0.010011151 0.128758672 2.46E-05 4.608311665 0.33917931 SNPTPMEPTS(ph)PGEHQQNSK ddPTM_HeLa_Curcumin_4h_R1 1 SNPTPMEPTSPGEHQQNSK 19 0 E7EUR8;A0A1B0GVL4;P78312-4;P78312-6;P78312-2;P78312-5;P78312 E7EUR8 FAM193A Protein FAM193A 1 0 S(0.001)NPT(0.004)PMEPT(0.077)S(0.918)PGEHQQNSK 69.525 0.0050119 11052000 2020.5 1902.6 1813.2 2008.4 1755 2957.5 2014.5 2387.8 2108.1 2055.4 TRUE FALSE FALSE 1860.575293 2067.052266 1880.398787 2000.089773 1734.072771 2344.081162 2071.021448 3115.829228 1876.846704 2126.824997 0.874813535 0.971895793 0.884134233 0.940411071 0.815334018 1.102150466 0.97376204 1.465014391 0.882464099 1 11.05448561 SNQNGKDSK(ac)PSSTPR ddPTM_HeLa_Curcumin_4h_R1 1 SNQNGKDSKPSSTPR 15 2 P06748;P06748-3 P06748 NPM1 Nucleophosmin 0 1 SNQNGK(0.462)DSK(0.538)PSSTPR 62.69 0.017993 639750 535.64 278.13 200.92 229.09 248.96 430.84 329.02 389.44 649.87 339.43 FALSE TRUE FALSE 493.2435288 302.1703179 208.3662719 228.1420863 245.9913146 341.4789274 338.2514157 508.1784632 578.5808869 351.2251672 1.404351324 0.860332192 0.593255528 0.649560759 0.70038066 0.972250736 0.963061441 1.446873717 1.647321835 1 8.456252415 -7.232282583 22.72137158 1.190943667 0.862909648 0.321625703 0.282477731 247.7699299 193082.3586 0.045596418 0.055835204 5.86E-08 7.232282583 -0.32803402 SNRDELELELAENRK ddPTM_HeLa_Curcumin_4h_R1 1 SNRDELELELAENRK 15 2 A0A087WY61;Q14980-2;Q14980;Q14980-5;Q14980-4;Q14980-3;F5H6Y5;F5H4J1 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 0 0 88.803 0.0033357 7283300 1397.5 1127.5 1247 1476.2 1318.3 1575 1510.4 831.54 1455.3 1432.2 FALSE FALSE TRUE 1286.8864 1224.956076 1293.214917 1470.091876 1302.580134 1248.327246 1552.777759 1085.072718 1295.657231 1481.968843 0.868362656 0.826573434 0.872632999 0.991985683 0.878952442 0.842343786 1.0477803 0.732183219 0.874281019 1 10.5332994 -9.259392467 0.985421503 1.000140743 0.887569765 0 0.090385956 0.650582885 1.131371454 0.051208008 0.013932883 5.50E-10 9.259392467 -0.112570978 SNS(ph)APLIHGLSDTSPVFQAEAPSAR ddPTM_HeLa_Curcumin_4h_R1 3 SNSAPLIHGLSDTSPVFQAEAPSAR 25 0 Q96E09 Q96E09 FAM122A Protein FAM122A 1 0 S(0.132)NS(0.867)APLIHGLSDTSPVFQAEAPSAR;S(0.266)NS(0.734)APLIHGLSDTSPVFQAEAPSAR;S(0.475)NS(0.525)APLIHGLSDTSPVFQAEAPSAR ;; 103.51 1.96E-07 212956500 8513.3 6932.5 6242.9 6282.1 8189.9 11428.2 7769.2 7365.2 8728.7 7082.9 TRUE FALSE FALSE 7839.463322 7531.714409 6474.267366 6256.106335 8092.240791 9057.862498 7987.182842 9610.815575 7771.183448 7329.030248 1.069645377 1.027654977 0.88337299 0.853606292 1.10413527 1.235888268 1.089800775 1.311335231 1.060329018 1 12.8394066 -5.523784925 24.99988498 1.008325778 1.195074779 0.585263948 0.085278095 19.3237811 533107.8927 0.012921811 0.026017891 2.99E-06 5.523784925 0.186749002 SQS(ph)MDIDGVSCEK ddPTM_HeLa_Curcumin_4h_R1 2 SQSMDIDGVSCEK 13 0 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 0 S(0.149)QS(0.85)MDIDGVS(0.001)CEK;S(0.002)QS(0.885)MDIDGVS(0.113)CEK ; 209.89 2.27E-09 101222000 9763.4 5830.8 8299.1 8735.5 8508.9 15307.6 17354.2 26823.8 7108.7 7478.9 TRUE FALSE FALSE 8990.616588 6334.78837 8606.671947 8699.354816 8407.436925 12132.63121 17841.11215 35002.25314 6328.893395 7738.791218 1.161759806 0.81857595 1.112146807 1.124123209 1.086401828 1.567768255 2.305413293 4.522961293 0.817814206 1 12.91789252 -3.945023448 1.121122946 1.057437388 8.542984912 0.986052224 0.126768617 0.19500504 0.123359591 0.016059621 2.032827894 0.000113495 3.945023448 7.485547524 up ELPPLS(ph)PSLSR ddPTM_HeLa_Curcumin_4h_R1 2 ELPPLSPSLSR 11 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 0 ELPPLS(0.988)PS(0.012)LSR;ELPPLS(0.908)PS(0.092)LSR ; 163.71 0.00028295 338020000 9419.2 7681.3 7399.1 8452.3 8685.4 9062.7 6131.2 1985.96 8870.8 6545.2 TRUE FALSE FALSE 8673.660381 8345.237345 7673.317155 8417.326622 8581.832278 7182.993862 6303.224971 2591.470062 7897.695434 6772.645213 1.280690204 1.232197625 1.13298673 1.242841808 1.267131528 1.060589125 0.930688789 0.3826378 1.16611681 1 12.72550371 -4.188416404 1.627734784 1.158485807 0.001494178 0.892283345 0.08364331 0.39809874 0.864869018 0.017090261 0.763396709 6.48E-05 4.188416404 -1.156991629 down SNS(ph)FIGVPNGEVEMPLK ddPTM_HeLa_Curcumin_4h_R1 1 SNSFIGVPNGEVEMPLK 17 0 Q9H7E2-2;Q9H7E2;Q9H7E2-3 Q9H7E2-2 TDRD3 Tudor domain-containing protein 3 1 0 S(0.451)NS(0.549)FIGVPNGEVEMPLK 78.441 0.010228 13001000 489.73 546.59 654.18 519.3 575.24 818.24 844.45 841.28 737.73 740.63 TRUE FALSE FALSE 450.9673537 593.834804 678.4244863 517.1512742 568.3806387 648.5278005 868.1429943 1097.782399 656.8028647 766.3668374 0.588448419 0.774870173 0.885247708 0.674809046 0.741656099 0.846236774 1.132803446 1.432450291 0.857034559 1 9.581891323 -4.519181251 1.992491223 0.790742282 1.472430284 0.786415742 0.107465844 0.222522294 1.352044253 0.022405054 0.227295578 3.03E-05 4.519181251 0.681688002 SNS(ph)FSDER ddPTM_HeLa_Curcumin_4h_R1 4 SNSFSDER 8 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 SNS(0.923)FS(0.077)DER;SNS(0.975)FS(0.025)DER;S(0.024)NS(0.952)FS(0.024)DER;S(0.015)NS(0.562)FS(0.424)DER ;;; 158.08 0.00068068 1791000000 32773.1 31281.8 32120.5 30169.4 39430.6 35843 30099.7 26506 28512.2 25989.3 TRUE FALSE FALSE 30179.07455 33985.6594 33310.91399 30044.56702 38960.41585 28408.75777 30944.21657 34587.55738 25384.48299 26892.42624 1.122214644 1.263763228 1.238672691 1.117212956 1.448750496 1.056385077 1.150666596 1.286144919 0.943926843 1 14.7149123 -7.980940807 0.853293356 1.020164917 1.220126006 0.445605887 0.105965001 0.36886577 0.580009572 0.030479892 0.023296326 1.04E-08 7.980940807 0.199961089 RDS(ph)VLTSK ddPTM_HeLa_Curcumin_4h_R1 1 RDSVLTSK 8 1 O75937 O75937 DNAJC8 DnaJ homolog subfamily C member 8 1 0 RDS(0.962)VLT(0.035)S(0.003)K 80.014 0.014981 12821000 2502.7 2586.4 2870.1 2546.5 3212.2 4115.6 4079.1 6049.7 2754.7 3239 TRUE FALSE FALSE 2304.608654 2809.956891 2976.468431 2535.963258 3173.896613 3261.978168 4193.548568 7894.225681 2452.516302 3351.555009 0.687623699 0.83840393 0.888085806 0.756652733 0.946992248 0.973273051 1.251224747 2.355391948 0.731754751 1 11.7106149 -3.939702745 1.332828216 0.848425719 4.190834173 0.960648091 0.092039097 0.471779871 0.41224282 0.017634399 2.617773278 0.000114894 3.939702745 3.342408454 up SNS(ph)LPHPAGGGK ddPTM_HeLa_Curcumin_4h_R1 1 SNSLPHPAGGGK 12 0 G5E9A7;Q09019 G5E9A7 DMWD Dystrophia myotonica WD repeat-containing protein 1 0 S(0.044)NS(0.956)LPHPAGGGK 104.17 0.0073116 18519000 2882.7 2496 2669.5 2861.5 2671.9 2700.1 2104.6 2318.7 2967.9 2964.7 TRUE FALSE FALSE 2654.531253 2711.743118 2768.434018 2849.659871 2640.039338 2140.068824 2163.649412 3025.660956 2642.328795 3067.723104 0.865309926 0.883959545 0.902439342 0.928916911 0.860585929 0.69760821 0.705294884 0.986288805 0.861332234 1 11.58295255 -13.52287875 0.117132775 1.537928434 0.756487328 0.039502123 0.094088415 79.42055201 0.675229604 10.08617718 0.43821223 3.00E-14 13.52287875 -0.781441106 S(ph)VSQDLIKK ddPTM_HeLa_Curcumin_4h_R1 1 SVSQDLIKK 9 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 S(0.999)VS(0.001)QDLIKK 87.184 0.0068748 0 707.45 460.39 642.77 709.66 611.63 948.35 876.56 1449.2 653.97 583.9 TRUE FALSE FALSE 651.454586 500.1840601 666.5916216 706.723615 604.3367117 751.6515199 901.1539145 1891.054409 582.2311272 604.1904815 1.078227158 0.827858226 1.103280575 1.169703325 1.000242027 1.244063822 1.491506308 3.129897717 0.963654915 1 9.238859646 -3.934764943 1.430327625 1.035449725 5.758048648 0.974867878 0.100377653 0.265539923 0.262630283 0.013827772 2.242946795 0.000116208 3.934764943 4.722598923 up SNS(ph)PLPVPPSK ddPTM_HeLa_Curcumin_4h_R1 5 SNSPLPVPPSK 11 0 Q13247-3;Q13247 Q13247-3 SRSF6 Serine/arginine-rich splicing factor 6 1 0 S(0.318)NS(0.681)PLPVPPSK;S(0.228)NS(0.772)PLPVPPSK;S(0.033)NS(0.966)PLPVPPS(0.001)K;S(0.001)NS(0.999)PLPVPPSK;S(0.112)NS(0.887)PLPVPPS(0.001)K ;;;; 153 0.00047945 1172806000 51571.3 43388.5 42639.3 44898.2 45929.3 48276.5 37102.7 29293.1 48908.5 40458.7 TRUE FALSE FALSE 47489.37719 47138.8086 44219.54997 44712.42314 45381.62309 38263.40971 38143.70191 38224.43134 43543.35991 41864.63681 1.134355408 1.125981549 1.056250653 1.068023672 1.084008522 0.913979258 0.911119857 0.913048201 1.040098833 1 15.35344449 -5.258023119 23.91920007 1.070604741 0.912556158 0.799790443 0.036664797 76.46720257 535383.6717 0.007603892 0.01853109 5.52E-06 5.258023119 -0.158048583 SNS(ph)QTLSDAPFTTCPEGPAR ddPTM_HeLa_Curcumin_4h_R1 1 SNSQTLSDAPFTTCPEGPAR 20 0 Q8IZW8 Q8IZW8 TNS4 Tensin-4 1 0 S(0.106)NS(0.446)QT(0.446)LS(0.002)DAPFTTCPEGPAR 132.01 0.00011995 0 650.54 509.92 353.58 759.34 490.85 445.28 457.67 650.17 718.57 455.27 TRUE FALSE FALSE 599.0490726 553.9952126 366.6839858 756.1980523 484.9969343 352.9239087 470.5109884 848.40384 639.7446688 471.0905986 1.271621795 1.175984438 0.77837254 1.605207267 1.029519451 0.749163557 0.998769642 1.800935621 1.358007718 1 8.879860731 -13.52262928 0.018918835 8.76E-05 2.011790588 0 0.323378242 11785.99749 17.98934999 1247.365798 730.5487232 3.00E-14 13.52262928 2.011702987 SNS(ph)RLEDQVIGVALQASK ddPTM_HeLa_Curcumin_4h_R1 1 SNSRLEDQVIGVALQASK 18 1 A0A3B3IRW6;Q2KHR3-2;Q2KHR3 A0A3B3IRW6 QSER1 Glutamine and serine-rich protein 1 1 0 S(0.203)NS(0.797)RLEDQVIGVALQASK 81.477 0.0025731 9989600 1802.4 1645.4 1620.1 1962.1 1865.5 1895.5 1393.8 4347.7 1668.5 1274.2 TRUE FALSE FALSE 1659.738138 1787.621044 1680.142331 1953.98135 1843.255131 1502.351933 1432.906277 5673.293716 1485.469724 1318.478355 1.258828506 1.355821305 1.274304068 1.481997291 1.398016982 1.139458928 1.086787865 4.302910012 1.126654616 1 10.36465817 -4.260264291 24.99936947 1.191961158 4.302911009 0.974666753 0.148193731 12.77964909 271846.2557 0.025328351 0.20938288 5.49E-05 4.260264291 3.110949851 SNS(ph)SEALLVDR ddPTM_HeLa_Curcumin_4h_R1 1 SNSSEALLVDR 11 0 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 0 S(0.019)NS(0.491)S(0.491)EALLVDR 150.05 0.00063109 22121000 1865.8 1511.2 1830.2 1657.7 1907.4 2866 1641.7 831.36 2143.4 2006.6 TRUE FALSE FALSE 1718.119961 1641.821394 1898.028822 1650.840877 1884.655501 2271.559294 1687.761684 1084.837837 1908.274383 2076.329201 0.827479554 0.7907327 0.914127115 0.795076656 0.907686267 1.09402656 0.812858425 0.522478727 0.919061574 1 11.01981948 -13.52287875 0.245554493 1.989802412 0.823872976 0.10856969 0.136575601 65.41843402 0.860365685 31.30786052 0.084998137 3.00E-14 13.52287875 -1.165929436 SNS(ph)SSEAVLGQEELSAQAK ddPTM_HeLa_Curcumin_4h_R1 1 SNSSSEAVLGQEELSAQAK 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 0 S(0.04)NS(0.956)S(0.004)SEAVLGQEELSAQAK 254.26 2.06E-43 33881000 748.37 663.58 581.67 662.91 536.84 676.35 337.19 415.61 787.14 726.28 TRUE FALSE FALSE 689.1357248 720.9368983 603.2272019 660.1670541 530.4385336 536.067386 346.6506439 542.3275758 700.7927113 751.5181759 0.916991427 0.959307335 0.802678127 0.878444561 0.705822628 0.713312603 0.461267146 0.72164266 0.932502678 1 9.553664187 -5.750345165 0.629222366 0.970016492 0.559003593 0.745601898 0.078007965 0.307796374 0.203787238 0.014743521 0.065406368 1.78E-06 5.750345165 -0.411012899 SNS(ph)TSSMSSGLPEQDR ddPTM_HeLa_Curcumin_4h_R1 2 SNSTSSMSSGLPEQDR 16 0 P42684-2;P42684-3;P42684-6;P42684 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 0 SNS(0.774)T(0.223)S(0.003)SMSSGLPEQDR;S(0.003)NS(0.971)T(0.026)SSMSSGLPEQDR ; 234.12 3.29E-22 34519000 3009.8 2330.08 2655.7 2497.6 2590.9 5463.1 3909.2 2570.12 3352.3 3100.3 TRUE FALSE FALSE 2771.571154 2531.481733 2754.122578 2487.265593 2560.00521 4329.991478 4018.881631 3353.737757 2984.561077 3208.035194 0.863946617 0.789106596 0.858507595 0.775323661 0.797997857 1.349733159 1.252754845 1.045418006 0.930339256 1 11.64747425 -5.26481085 24.99797982 0.896861231 1.219647291 0.722393697 0.099420066 139.2240543 1032290.03 0.016281936 0.037839217 5.43E-06 5.26481085 0.32278606 SNS(ph)TTQVSQPR ddPTM_HeLa_Curcumin_4h_R1 3 SNSTTQVSQPR 11 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 0 S(0.001)NS(0.488)T(0.488)T(0.022)QVSQPR;S(0.01)NS(0.372)T(0.372)T(0.244)QVS(0.001)QPR;S(0.011)NS(0.477)T(0.477)T(0.034)QVSQPR ;; 157.33 0.00039995 264692000 4890.5 3625.4 4502.9 4305.7 3961.8 5471.3 4184.4 4638.1 4085.8 3945 TRUE FALSE FALSE 4503.411765 3938.763422 4669.781435 4287.884154 3914.558123 4336.490706 4301.803002 6052.235339 3637.597962 4082.088456 1.103212685 0.964889287 1.143968703 1.050414316 0.958959651 1.062321592 1.053824053 1.48263209 0.891111989 1 11.99509173 -4.261156373 6.40176317 1.045375336 1.491948586 0.776374242 0.072924953 0.034278195 8.048066914 0.007831015 0.065961085 5.48E-05 4.261156373 0.44657325 SNS(ph)VGIQDAFNDGSDSTFQKR ddPTM_HeLa_Curcumin_4h_R1 1 SNSVGIQDAFNDGSDSTFQKR 21 1 O14497;O14497-2;H0Y488;A0A1B0GTU5;O14497-3;A0A087WUV6 O14497 ARID1A AT-rich interactive domain-containing protein 1A 1 0 S(0.023)NS(0.525)VGIQDAFNDGS(0.446)DS(0.004)T(0.002)FQKR 77.276 0.00072735 39440000 1686 1080.1 1589.5 1621.8 1347.8 1253.2 1098.2 2601.7 1916.9 1649.9 TRUE FALSE FALSE 1552.551321 1173.459031 1648.408268 1615.089421 1331.728365 993.2721935 1129.012536 3394.946353 1706.620866 1707.233902 0.909395789 0.687345202 0.965543307 0.946027032 0.780050328 0.581802056 0.661310987 1.98856545 0.999640918 1 10.73744502 -4.254202547 24.88903932 0.886602146 1.988566 0.835522613 0.151866828 271.5039649 933736.6863 0.0232397 0.317236144 5.57E-05 4.254202547 1.101963854 SNSFS(ph)DER ddPTM_HeLa_Curcumin_4h_R1 1 SNSFSDER 8 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 SNS(0.006)FS(0.994)DER 169.21 0.00080995 1481400000 8512.3 8469.2 8205.1 8295.6 10571 9202.5 8258.8 7057.5 7635.9 6970.8 TRUE FALSE FALSE 7838.542473 9201.23991 8509.188224 8261.275005 10444.94773 7293.797766 8490.519701 9209.299261 6798.260874 7213.034781 1.086719073 1.275640585 1.179695992 1.145325824 1.448065626 1.011196811 1.177107827 1.276757917 0.942496616 1 12.81639067 -7.534676834 2.231278982 1.031805466 1.211645744 0.417626452 0.110845915 0.222795486 2.234250166 0.019582176 0.021023571 2.92E-08 7.534676834 0.179840278 SNSGLATYS(ph)PPMGPVSER ddPTM_HeLa_Curcumin_4h_R1 4 SNSGLATYSPPMGPVSER 18 0 H0Y465;P21359-2;P21359-6;P21359;J3KSB5;P21359-4 H0Y465 NF1 Neurofibromin;Neurofibromin truncated 1 0 SNSGLAT(0.218)Y(0.155)S(0.626)PPMGPVSER;SNSGLAT(0.032)Y(0.409)S(0.559)PPMGPVSER;SNSGLAT(0.051)Y(0.043)S(0.907)PPMGPVSER;SNSGLAT(0.051)Y(0.408)S(0.539)PPMGPVS(0.001)ER ;;; 121.51 0.00038712 64154700 13715.6 10963.5 12352.8 13885.5 12976.7 15252.6 11469.5 8776.8 14183.7 14394.9 TRUE FALSE FALSE 12629.99579 11911.13609 12810.60563 13828.04548 12821.96133 12089.03883 11791.3033 11452.80592 12627.7836 14895.1217 0.847928338 0.799666919 0.860053774 0.928360691 0.860816151 0.811610611 0.791621817 0.768896431 0.84777982 1 13.86255229 -13.52287875 0.168530603 1.680242343 0.788928214 0.079097009 0.062805026 25.31997292 0.279412863 5.64344369 0.074526105 3.00E-14 13.52287875 -0.891314129 ETES(ph)APGSPR ddPTM_HeLa_Curcumin_4h_R1 2 ETESAPGSPR 10 0 Q6PKG0;A0A0B4J210;Q6PKG0-3;E5RH50;H0YBW1 Q6PKG0 LARP1 La-related protein 1 1 0 ET(0.303)ES(0.697)APGSPR;ETES(1)APGSPR ; 184.44 0.00021932 157800000 5788.3 5183.5 5249.6 5485.5 5817.7 8685.6 8688.2 14099.5 5579.6 5608.6 TRUE FALSE FALSE 5330.149947 5631.538643 5444.154794 5462.802454 5748.327727 6884.108653 8931.967509 18398.37264 4967.531839 5803.498433 0.918437389 0.970369633 0.938081548 0.941294724 0.990493544 1.186199795 1.539066067 3.170221007 0.855954714 1 12.50270712 -3.934263819 1.32903299 0.959240151 5.90342605 0.992763697 0.056687096 0.1398219 0.12027116 0.00755199 1.148675034 0.000116342 3.934263819 4.944185899 up SNSIDGS(ph)NVTVT(ph)PGPGEQTVDVEPR ddPTM_HeLa_Curcumin_4h_R1 1 SNSIDGSNVTVTPGPGEQTVDVEPR 25 0 Q05GC8;Q96PN7-2;Q96PN7-3;Q96PN7-4;Q96PN7-5;Q96PN7 Q05GC8 BCAR2;TRERF1 Transcriptional-regulating factor 1 2 0 S(0.002)NS(0.007)IDGS(0.991)NVT(0.026)VT(0.974)PGPGEQTVDVEPR 127.76 5.25E-08 3474600 1320.7 770.87 846.98 1068.5 960.49 1272.3 1207.6 910.62 981.13 999.84 TRUE FALSE FALSE 1216.165201 837.5005679 878.3698239 1064.07883 949.0367841 1008.410638 1241.482006 1188.263846 873.5024937 1034.584366 1.175510903 0.809504373 0.84900744 1.028508516 0.917312126 0.974701215 1.19998141 1.148542241 0.844302816 1 10.01483558 -4.755155553 24.99220454 1.026796958 1.174261874 0.18030828 0.122878008 204.1456178 811909.9705 0.018478983 0.065835036 1.76E-05 4.755155553 0.147464916 ESAAPAAAPTAEAPPPSVVTRPEPQALPS(ph)PAIR ddPTM_HeLa_Curcumin_4h_R1 2 ESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIR 33 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 1 0 ESAAPAAAPT(0.001)AEAPPPS(0.089)VVT(0.068)RPEPQALPS(0.842)PAIR;ESAAPAAAPT(0.041)AEAPPPS(0.303)VVT(0.303)RPEPQALPS(0.354)PAIR ; 71.289 8.64E-06 223965000 5704.1 4583.6 5443.3 5426.4 5251.8 9823.4 10898.6 15425.9 5649.4 4544.2 TRUE FALSE FALSE 5252.614466 4979.78596 5645.033486 5403.946995 5189.175715 7785.916107 11204.38538 20129.1859 5029.674954 4702.110612 1.117075905 1.059053342 1.200531836 1.149259862 1.103584357 1.655834316 2.38284173 4.28088311 1.069663258 1 12.19909276 -3.918627579 1.001103544 1.064610831 8.180524754 0.994657197 0.071540508 0.168838513 0.082662783 0.011832248 1.515612754 0.000120607 3.918627579 7.115913923 up SNSLS(ph)EQLAINT(ph)SPDAVK ddPTM_HeLa_Curcumin_4h_R1 1 SNSLSEQLAINTSPDAVK 18 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 2 0 S(0.052)NS(0.334)LS(0.614)EQLAINT(0.938)S(0.062)PDAVK 80.362 0.0090078 0 909.19 569.69 736.26 872.5 764.27 882.08 639.56 506.12 879.77 770.94 TRUE FALSE FALSE 837.2266521 618.9314651 763.5464433 868.8898262 755.1565794 699.1266649 657.5043323 660.4336581 783.2614321 797.7301076 1.049511162 0.775865746 0.957148835 1.089202749 0.946631664 0.876394984 0.824219026 0.827891102 0.981862693 1 9.639756918 -3.244650156 0.34710955 1.018121797 0.408461443 0.277546676 0.083451558 9.407684145 0.464622159 0.027589137 2.783444412 0.000569311 3.244650156 -0.609660353 SNSLSEQLAINT(ph)SPDAVK ddPTM_HeLa_Curcumin_4h_R1 1 SNSLSEQLAINTSPDAVK 18 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 0 S(0.006)NS(0.024)LS(0.139)EQLAINT(0.644)S(0.188)PDAVK 135.1 0.00079418 4706500 2336.2 2185.7 2195.8 2076.7 2372.7 2764.3 1710.1 792.91 2900.7 1920.9 TRUE FALSE FALSE 2151.287305 2374.622169 2277.17828 2068.107166 2344.407102 2190.95302 1758.080804 1034.664609 2582.500467 1987.651132 1.082326405 1.194687604 1.14566296 1.040477945 1.179486211 1.10228248 0.884501699 0.520546384 1.299272506 1 10.95684885 -4.348677355 2.417278494 1.071742229 0.448792211 0.780363636 0.096366396 0.130280258 1.049872204 0.010885888 0.154417017 4.48E-05 4.348677355 -0.622950018 SNSLSEQLAINTS(ph)PDAVK ddPTM_HeLa_Curcumin_4h_R1 2 SNSLSEQLAINTSPDAVK 18 0 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 0 SNSLSEQLAINT(0.071)S(0.929)PDAVK;SNSLSEQLAINT(0.006)S(0.994)PDAVK ; 335.98 3.91E-152 82854000 11885.7 9696.9 10088.1 9939.1 10331.1 15392.1 10846.5 8779.7 11627.3 8591 TRUE FALSE FALSE 10944.9343 10535.05683 10461.97386 9897.974638 10207.90838 12199.60496 11150.8236 11456.59011 10351.81428 8889.536611 1.231215392 1.185107536 1.176886301 1.113441012 1.148306017 1.372355556 1.25437625 1.288772477 1.164494251 1 13.1178925 -13.52287875 0.177975065 0.059609538 1.279580951 0.272997451 0.082348192 28.84198576 0.328868123 9.431283079 0.101322968 3.00E-14 13.52287875 1.219971413 SNSQSDSHDEEVS(ph)PTPPNPVVK ddPTM_HeLa_Curcumin_4h_R1 4 SNSQSDSHDEEVSPTPPNPVVK 22 0 C9J4C2;C9IZL8;C9JR00;C9JSK5;P31321 C9J4C2 PRKAR1B cAMP-dependent protein kinase type I-beta regulatory subunit 1 0 SNSQSDSHDEEVS(0.996)PT(0.004)PPNPVVK;SNSQSDSHDEEVS(0.999)PT(0.001)PPNPVVK;SNSQSDSHDEEVS(0.983)PT(0.017)PPNPVVK;SNSQSDSHDEEVS(0.738)PT(0.262)PPNPVVK ;;; 160.12 3.11E-07 93054000 8911.6 7578.9 6348.7 5850.51 12139.8 18091.6 8982.6 6680.2 11155.6 6754.9 TRUE FALSE FALSE 8206.237457 8233.986345 6583.988407 5826.30214 11995.04081 14339.19823 9234.627581 8716.962228 9931.85859 6989.632272 1.174058539 1.178028546 0.94196492 0.833563471 1.71611901 2.051495367 1.32118933 1.247127444 1.420941504 1 12.77100084 -5.753916292 24.99862293 1.064869121 1.59860565 0.472740084 0.253721558 101.7126991 337980.2394 0.034483232 0.067897206 1.76E-06 5.753916292 0.533736529 SNSS(ph)EALLVDR ddPTM_HeLa_Curcumin_4h_R1 1 SNSSEALLVDR 11 0 Q96HB5-2;Q96HB5;Q96HB5-5;Q96HB5-3;Q96HB5-4 Q96HB5-2 CCDC120 Coiled-coil domain-containing protein 120 1 0 S(0.013)NS(0.314)S(0.673)EALLVDR 155.37 0.00043591 23883000 2439.1 1767.1 2068.2 2090.3 2278.7 3536.3 2010.9 891.61 2548.8 2581.3 TRUE FALSE FALSE 2246.042661 1919.84025 2144.849311 2081.650892 2251.527991 2802.831518 2067.320442 1163.457785 2269.203017 2670.999983 0.840899542 0.718772094 0.8030136 0.779352642 0.842953203 1.049356621 0.773987441 0.43558884 0.849570585 1 11.38316425 -13.52287875 0.033212673 2.221455388 2.24E-13 0.17438907 0.143029401 943.5866331 2.512193803 133.3458297 52.31333984 3.00E-14 13.52287875 -2.221455388 SNSS(ph)SEAVLGQEELSAQAK ddPTM_HeLa_Curcumin_4h_R1 1 SNSSSEAVLGQEELSAQAK 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 0 S(0.003)NS(0.283)S(0.706)S(0.008)EAVLGQEELSAQAK 229.37 5.60E-25 56716000 2738.5 2276.1 2908.3 2348.6 2895 3156 1939.8 1347.2 3459.7 2928.3 TRUE FALSE FALSE 2521.744835 2472.835942 3016.084156 2338.882115 2860.479016 2501.410025 1994.225567 1757.955078 3080.179566 3030.058207 0.832243034 0.816101795 0.995388191 0.771893461 0.944034345 0.825532004 0.65814761 0.580172049 1.016541385 1 11.56512979 -3.659784458 0.597753525 0.917189012 4.18E-19 0.671698968 0.080550473 2.98983466 0.439662179 0.015306582 2.226753498 0.000218885 3.659784458 -0.917189012 SNSTS(ph)SMSSGLPEQDR ddPTM_HeLa_Curcumin_4h_R1 1 SNSTSSMSSGLPEQDR 16 0 P42684-2;P42684-3;P42684-6;P42684 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 0 SNS(0.003)T(0.179)S(0.354)S(0.087)MS(0.354)S(0.022)GLPEQDR 90.697 0.0062085 9830800 3961.6 3084.6 3287.3 3192.1 3698.6 5426.9 4937.8 3225.5 3517 3221.9 TRUE FALSE FALSE 3648.03518 3351.219079 3409.13023 3178.891936 3654.496611 4301.299766 5076.341379 4208.940102 3131.193899 3333.860785 1.094237407 1.005206664 1.022577261 0.953516701 1.096175529 1.290185777 1.522661474 1.262482261 0.939209553 1 11.70297815 -5.21336407 2.939486061 1.034746519 1.39443619 0.812232695 0.076304371 0.074368013 1.271190827 0.009838512 0.027672989 6.12E-06 5.21336407 0.359689671 SNSWVNT(ph)GGPK ddPTM_HeLa_Curcumin_4h_R1 2 SNSWVNTGGPK 11 0 Q96N67-2;Q96N67-6;Q96N67;A0A1B0GWE0;A0A0U1RRC1 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 S(0.115)NS(0.005)WVNT(0.88)GGPK;S(0.001)NSWVNT(0.999)GGPK ; 169.09 0.00071499 110500000 9795 7688.6 9036 9881.3 8979.8 11293.5 9032.8 8153.3 9513.7 9612.5 TRUE FALSE FALSE 9019.715414 8353.168324 9370.882109 9840.413799 8872.72175 8951.100796 9286.236057 10639.20364 8470.070912 9946.53366 0.906819976 0.839806973 0.942125411 0.989330971 0.892041595 0.899921631 0.933615305 1.069639334 0.851560071 1 13.27997812 -9.376293934 1.172640676 0.998930286 0.928899196 0 0.074276765 0.67504826 1.69856795 0.036908151 0.010122877 4.20E-10 9.376293934 -0.070031091 SNT(ph)LDIMDGR ddPTM_HeLa_Curcumin_4h_R1 4 SNTLDIMDGR 10 0 O94915;H0Y9X0;A0A286YEZ9;A0A2C9F2R7 O94915 FRYL Protein furry homolog-like 1 0 SNT(1)LDIMDGR;SNT(1)LDIMDGR;S(0.083)NT(0.917)LDIMDGR;S(0.409)NT(0.591)LDIMDGR ;;; 154.1 0.0018802 150242000 11757 10558.7 10373.1 10879.4 10021.5 13898.3 10856 5296.37 12127.3 11361.6 TRUE FALSE FALSE 10826.42104 11471.34698 10757.53621 10834.38393 9902.000158 11015.63591 11160.59014 6911.208832 10796.96553 11756.41475 0.920894786 0.975752151 0.915035445 0.921572108 0.842263595 0.936989392 0.949319191 0.587867048 0.918389301 1 13.52116054 -4.261160688 24.42439606 0.946508579 0.587866898 0.854178472 0.0421203 4.878649727 427249.936 0.006821918 0.05330164 5.48E-05 4.261160688 -0.358641681 SNT(ph)PESIAETPPAR ddPTM_HeLa_Curcumin_4h_R1 2 SNTPESIAETPPAR 14 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 S(0.023)NT(0.974)PESIAET(0.003)PPAR;S(0.014)NT(0.962)PES(0.004)IAET(0.02)PPAR ; 202.92 1.61E-08 128140000 8794.1 7737.8 8522.4 7859.5 7333.4 6712.7 4193.8 3686.4 8828.8 7427.3 TRUE FALSE FALSE 8098.037706 8406.620953 8838.247641 7826.979471 7245.953995 5320.410352 4311.466741 4810.36639 7860.302729 7685.398122 1.053691374 1.093843262 1.150005179 1.018422123 0.942820903 0.692275178 0.560994586 0.625909851 1.022758041 1 12.90790428 -5.267323319 2.138723916 1.04148739 0.590959226 0.949470913 0.044689189 0.056188195 0.49439663 0.007621599 0.023043939 5.40E-06 5.267323319 -0.450528163 SNT(ph)PILVDGK ddPTM_HeLa_Curcumin_4h_R1 2 SNTPILVDGK 10 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YX90;A0A0J9YYH3;K7EPY4;K7EP41;K7ERC6 P06744-2 GPI Glucose-6-phosphate isomerase 1 0 S(0.001)NT(0.999)PILVDGK;S(0.005)NT(0.995)PILVDGK ; 168.76 0.0014812 46317000 11792.9 10656.1 12449.8 10826.8 14325.5 12575.9 12179.5 11156 10495.7 9802.1 TRUE FALSE FALSE 10859.47952 11577.1658 12911.20054 10782.00157 14154.67777 9967.51658 12521.22399 14557.41304 9344.347969 10142.72225 1.07066715 1.141425893 1.272952194 1.063028377 1.395550171 0.982725972 1.234503291 1.435256994 0.921285996 1 13.30815729 -1 0.120030258 0.911789976 2.203783909 0.447509247 0.124514198 65.34043638 0.5394144 0.514568292 14.17465536 0.1 1 1.291993933 SNT(ph)PILVDGKDVMPEVNK ddPTM_HeLa_Curcumin_4h_R1 1 SNTPILVDGKDVMPEVNK 18 1 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YX90;A0A0J9YYH3;K7EPY4;K7EP41;K7ERC6 P06744-2 GPI Glucose-6-phosphate isomerase 1 0 S(0.091)NT(0.909)PILVDGKDVMPEVNK 64.318 0.017192 69911000 2380 2108 2812.3 2397.7 2481.7 2570.7 2215.7 1908.7 2379.2 2248.5 TRUE FALSE FALSE 2191.620489 2290.206127 2916.526312 2387.778953 2452.107348 2037.507842 2277.866579 2490.653843 2118.207712 2326.635208 0.941969967 0.98434259 1.253538287 1.026279902 1.053928583 0.875731544 0.979038988 1.070496069 0.910416771 1 11.18402931 -3.278999965 2.917129637 0.994857037 10.88987861 0.034699633 0.097980829 873.4330563 59.90221203 0.013671364 56632.51148 0.000526017 3.278999965 9.895021576 SNT(ph)PMGDKDDDDDDDADEK ddPTM_HeLa_Curcumin_4h_R1 1 SNTPMGDKDDDDDDDADEK 19 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;X6RE05;A0A0A0MSW0 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 0 S(0.05)NT(0.95)PMGDKDDDDDDDADEK 89.344 0.0017706 30956000 2622.3 3260.4 3403.4 3407.2 3569.8 3239.7 2212.5 2145.9 3238.1 4030 TRUE FALSE FALSE 2414.742188 3542.214448 3529.532998 3393.101909 3527.232467 2567.749701 2274.576795 2800.175031 2882.888531 4170.0422 0.579069005 0.84944331 0.846402225 0.813685269 0.845850545 0.615761083 0.545456541 0.671498008 0.691333179 1 12.02584627 -9.511826117 1.22606147 1.002118593 0.710459559 0 0.144605021 0.367226736 0.976520216 0.090989875 0.021285568 3.08E-10 9.511826117 -0.291659034 SNTAGS(ph)QSQVETEA ddPTM_HeLa_Curcumin_4h_R1 2 SNTAGSQSQVETEA 14 0 Q02790 Q02790 FKBP4 "Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed" 1 0 S(0.012)NT(0.003)AGS(0.912)QS(0.073)QVETEA;S(0.005)NT(0.002)AGS(0.928)QS(0.065)QVETEA ; 155.09 0.00040009 49945000 4182.7 3960.5 3591.3 3863.6 3506.4 4569.8 5029.1 5191.6 4110.6 4066.9 TRUE FALSE FALSE 3851.634881 4302.827972 3724.396737 3847.613447 3464.58847 3621.971968 5170.203011 6774.494941 3659.677464 4208.224472 0.915263648 1.022480621 0.885028059 0.914308035 0.823289844 0.86068887 1.228594873 1.609822619 0.869648824 1 12.03899595 -4.438329293 2.715106361 0.940331097 1.631229918 0.913311194 0.067033337 0.071828786 0.86154855 0.010010085 0.091034845 3.64E-05 4.438329293 0.690898821 SNTAGSQSQVETEA ddPTM_HeLa_Curcumin_4h_R1 1 SNTAGSQSQVETEA 14 0 Q02790 Q02790 FKBP4 "Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed" 0 0 154.28 0.00087682 1279700 808.47 549.88 618.16 701.92 694.41 839.52 432.17 587.77 708.27 464.2 FALSE FALSE TRUE 744.4787464 597.409177 641.0695534 699.015641 686.1296143 665.3940887 444.2955271 766.9783672 630.574553 480.3309154 1.549928856 1.243745005 1.334641458 1.455279305 1.428451911 1.385282661 0.924977995 1.596770773 1.312791937 1 8.907884857 -9.517990691 1.259925961 0.999159868 1.374007511 0.071170018 0.199434034 0.383394951 1.085601952 0.123632601 0.02944613 3.03E-10 9.517990691 0.374847644 (ac)S(ph)KGPAVGIDLGTTYSCVGVFQHGK ddPTM_HeLa_Curcumin_4h_R1 2 SKGPAVGIDLGTTYSCVGVFQHGK 24 1 P11142;E9PKE3;E9PNE6;P11142-2;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PPY6;E9PN25;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 1 0 S(0.478)KGPAVGIDLGT(0.454)T(0.058)Y(0.008)S(0.002)CVGVFQHGK;S(0.949)KGPAVGIDLGT(0.019)T(0.023)Y(0.006)S(0.002)CVGVFQHGK ; 52.061 2.98E-06 67124000 4438.1 3481.1 3894.5 3787.8 4125.8 6378.8 5554.1 7484.6 4772.8 4357.5 TRUE FALSE FALSE 4086.819702 3781.990773 4038.833596 3772.127087 4076.60253 5055.764976 5709.933098 9766.620085 4249.235781 4508.922801 0.906384936 0.838779225 0.895742459 0.836591633 0.904118946 1.121280004 1.266363021 2.166065049 0.942405973 1 12.13856709 -3.915151275 1.258994684 0.930390423 3.755059963 0.97258966 0.063112347 0.387765752 0.290823547 0.010995993 1.745251392 0.000121576 3.915151275 2.824669541 up SNTEPQSPPIAS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SNTEPQSPPIASPK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 0 SNTEPQSPPIAS(1)PK;SNTEPQS(0.004)PPIAS(0.996)PK ; 214.63 8.98E-14 30459100 10906.9 8385.1 10041.5 10750.1 9595.7 10412.2 8605.2 10731.7 10865.3 10180 TRUE FALSE FALSE 10043.60736 9109.870681 10413.64682 10705.61893 9481.277545 8252.59235 8846.638752 14003.74593 9673.403774 10533.75424 0.953468927 0.864826582 0.988597853 1.016315616 0.900085319 0.783442651 0.839837208 1.329416427 0.918324422 1 13.36273209 -8.810672908 0.985968569 0.996525295 0.948482898 0 0.14345684 2.139567527 4.117050495 0.059394533 0.026465466 1.55E-09 8.810672908 -0.048042397 SNVSDAVAQSTR ddPTM_HeLa_Curcumin_4h_R1 2 SNVSDAVAQSTR 12 0 P60174;P60174-3;P60174-4 P60174 TPI1 Triosephosphate isomerase 0 0 ; ; 168.85 1.38E-06 10149700 3562.5 2561.6 3280.8 2874.7 3097.7 4333 3113.9 3302.4 3404.5 2611.2 FALSE FALSE TRUE 3280.524366 2783.01329 3402.389334 2862.805253 3060.761951 3434.286957 3201.267653 4309.286558 3031.034868 2701.939006 1.214137092 1.030005964 1.259239874 1.059537335 1.132802015 1.271045331 1.184803819 1.59488669 1.121799886 1 11.39977939 -1.00000001 0.785689631 1.107462996 106.8862581 0.720394392 0.085662936 197.3823763 0.688786437 0.015677813 37136.26821 0.099999998 1.00000001 105.7787952 SNVSS(ph)PAT(ph)PTASSSSSTTPTR ddPTM_HeLa_Curcumin_4h_R1 1 SNVSSPATPTASSSSSTTPTR 21 0 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 SNVS(0.048)S(0.952)PAT(0.565)PT(0.338)AS(0.067)S(0.011)S(0.003)S(0.002)S(0.001)T(0.001)T(0.011)PT(0.002)R 105.95 0.00074842 0 715.72 620.62 683.46 640.52 665.73 558.68 633.88 706.01 697.15 714.91 TRUE FALSE FALSE 659.0700068 674.2636274 708.7896288 637.869698 657.7916046 442.8034704 651.6649668 921.2691989 620.6743892 739.7530693 0.89093244 0.911471213 0.958143546 0.862273811 0.889204292 0.598582809 0.880922289 1.245373946 0.83902915 1 9.530899967 -9.257408577 0.572018407 1.018007183 0.890235814 0 0.155576678 3.042626165 1.41801716 0.20863384 0.03508002 5.53E-10 9.257408577 -0.127771369 SVS(ph)ENSLVAMDFSGQTGR ddPTM_HeLa_Curcumin_4h_R1 4 SVSENSLVAMDFSGQTGR 18 0 A0A2R8YCL1;Q13322-3;Q13322-2;Q13322-4;Q13322 A0A2R8YCL1 GRB10 Growth factor receptor-bound protein 10 1 0 S(0.002)VS(0.939)ENS(0.059)LVAMDFSGQTGR;SVS(0.926)ENS(0.074)LVAMDFSGQTGR;SVS(0.967)ENS(0.033)LVAMDFSGQTGR;S(0.026)VS(0.835)ENS(0.138)LVAMDFS(0.001)GQTGR ;;; 156 5.95E-05 98709000 11142.4 9333.9 9517 11081.4 9465.1 11742.6 7316.6 2799.52 11379.1 9622.6 TRUE FALSE FALSE 10260.46728 10140.68072 9869.708392 11035.5481 9352.234864 9307.052394 7521.884104 3653.080761 10130.8412 9956.984634 1.030479373 1.018448968 0.991234671 1.108322299 0.939263764 0.934725997 0.755437954 0.366886251 1.017460765 1 13.28149319 -4.188047353 1.24174913 1.017077174 5.62E-20 0.965610234 0.037631912 0.193732857 0.221679173 0.005267417 0.262151529 6.49E-05 4.188047353 -1.017077174 down SNVSSPAT(ph)PT(ph)ASSSSSTTPTR ddPTM_HeLa_Curcumin_4h_R1 1 SNVSSPATPTASSSSSTTPTR 21 0 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 SNVSSPAT(0.947)PT(0.269)AS(0.147)S(0.11)S(0.113)S(0.025)S(0.168)T(0.126)T(0.095)PT(0.002)R 124.77 5.48E-05 10997000 2292.1 2146.8 2039.3 2282.9 2112.3 2598.2 2284.8 911.87 2719.9 2097.7 TRUE FALSE FALSE 2110.677866 2332.359826 2114.878252 2273.453965 2087.112202 2059.304032 2348.905339 1189.894965 2421.533775 2170.594919 0.972396023 1.074525609 0.974331154 1.04738749 0.961539246 0.948727934 1.082148179 0.548188404 1.115608331 1 11.0838748 -4.254683446 24.95288357 0.996260312 0.548188194 0.848310463 0.059067244 155.099059 572839.4943 0.005754043 0.074842807 5.56E-05 4.254683446 -0.448072118 VVSSVSSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 VVSSVSSSPR 10 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 0 VVSS(0.006)VS(0.022)S(0.075)S(0.896)PR;VVSSVS(0.008)S(0.027)S(0.964)PR ; 126.03 0.003523 167887000 15044.8 10119.7 12684.2 14789.6 13284.5 15117.7 10421.6 3377.7 13604.1 12837.1 TRUE FALSE FALSE 13853.9882 10994.40178 13154.28761 14728.40455 13126.09101 11982.11861 10714.00205 4407.545181 12111.76427 13283.18827 1.042971606 0.827692987 0.990295955 1.108800407 0.988173227 0.902051403 0.806583618 0.3318138 0.911811534 1 13.69731385 -4.187916303 1.452222601 1.00693554 2.91E-21 0.863758389 0.076191694 0.320472895 0.529115661 0.010345747 0.488360543 6.49E-05 4.187916303 -1.00693554 down ATS(ph)VDYSSFADR ddPTM_HeLa_Curcumin_4h_R1 1 ATSVDYSSFADR 12 0 Q86YS7-3;Q86YS7-2;Q86YS7-4 Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 0 AT(0.112)S(0.752)VDYS(0.136)SFADR 180.61 1.98E-14 0 1697.4 1115.5 1322.7 1177.2 1329.1 2085.4 1666.3 2688.9 1316.2 1213.2 TRUE FALSE FALSE 1563.048999 1211.918849 1371.720426 1172.329058 1313.251351 1652.864533 1713.051893 3508.733232 1171.816153 1255.35861 1.245101588 0.965396533 1.092692092 0.933859894 1.046116496 1.316647307 1.364591663 2.795004714 0.933451321 1 10.29388383 -3.913731491 1.52204896 1.091575569 5.125812047 0.948485665 0.120333087 0.457700251 0.485274879 0.018341143 3.577407546 0.000121974 3.913731491 4.034236478 up SNVSSPAT(ph)PTASSSSSTTPTRK ddPTM_HeLa_Curcumin_4h_R1 3 SNVSSPATPTASSSSSTTPTRK 22 1 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 S(0.014)NVS(0.063)S(0.138)PAT(0.753)PT(0.017)AS(0.001)S(0.001)S(0.001)S(0.001)S(0.001)T(0.003)T(0.003)PT(0.004)RK;SNVS(0.005)S(0.047)PAT(0.939)PT(0.008)ASSSSSTTPTRK;SNVSS(0.003)PAT(0.995)PT(0.001)ASSSSSTTPTRK ;; 113.63 7.12E-06 31473000 9830.6 7188.8 8044.8 8417 7526.4 8955 6440.27 6758.42 9296.6 7411 TRUE FALSE FALSE 9052.497637 7810.167839 8342.947365 8382.172684 7436.652596 7097.632056 6620.966643 8819.031146 8276.786239 7668.531698 1.180473393 1.018469786 1.087945867 1.093060968 0.969762255 0.92555294 0.863394311 1.150028649 1.079318253 1 12.90473465 -5.756388966 22.29617788 1.082361811 0.965368576 0.255708937 0.081700149 33.71054552 148814.1974 0.013351586 0.025997339 1.75E-06 5.756388966 -0.116993236 SVSPESNDS(ph)ISEELNHFKPIVCSPCTPPK ddPTM_HeLa_Curcumin_4h_R1 1 SVSPESNDSISEELNHFKPIVCSPCTPPK 29 1 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 0 S(0.019)VS(0.069)PES(0.356)NDS(0.442)IS(0.112)EELNHFKPIVCS(0.002)PCTPPK 59.661 0.00089737 13140000 4961.3 4482.5 4431.8 4434.2 4499.7 5186.2 3032.9 1436 5633.2 4574.2 TRUE FALSE FALSE 4568.60787 4869.947326 4596.046407 4415.852455 4446.044016 4110.523659 3117.995011 1873.829789 5015.252054 4733.15311 0.965235598 1.028901287 0.971032692 0.932962098 0.93934084 0.868453558 0.658756423 0.395894607 1.059600638 1 12.20858588 -4.187644185 0.952445546 0.984761207 2.74E-15 0.972591951 0.032021099 0.176579336 0.110363135 0.003564617 0.184602069 6.49E-05 4.187644185 -0.984761207 down SNVSSPATPT(ph)ASSSSSTTPTR ddPTM_HeLa_Curcumin_4h_R1 2 SNVSSPATPTASSSSSTTPTR 21 0 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 SNVSSPAT(0.08)PT(0.819)AS(0.08)S(0.021)S(0.001)SSTTPTR;SNVSSPAT(0.001)PT(0.333)AS(0.102)S(0.148)S(0.067)S(0.067)S(0.031)T(0.031)T(0.218)PTR ; 270.35 2.14E-59 34324000 5671.1 4010.12 3832.82 4945.2 4528.4 5403.1 4590.1 2789.1 5048.6 4450.93 TRUE FALSE FALSE 5222.226451 4356.736904 3974.867681 4924.738073 4474.401788 4282.436155 4718.885852 3639.483751 4494.781211 4605.599486 1.133886363 0.945965214 0.863051095 1.069293604 0.971513437 0.929832515 1.024597529 0.790230189 0.97593836 1 12.16917324 -7.236074206 23.54519354 1.063224114 0.947759166 0.189617025 0.083763767 341.7924835 317268.3537 0.013827842 0.016930928 5.81E-08 7.236074206 -0.115464948 SNVSSPATPTASS(ph)SSSTTPTR ddPTM_HeLa_Curcumin_4h_R1 1 SNVSSPATPTASSSSSTTPTR 21 0 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 SNVSSPAT(0.001)PT(0.05)AS(0.078)S(0.244)S(0.122)S(0.122)S(0.122)T(0.122)T(0.14)PT(0.001)R 137.85 4.14E-05 15123000 3312.7 2815.6 2884.8 3406.3 2948.7 4225.7 2799.6 1664.2 3328.4 3183.4 TRUE FALSE FALSE 3050.496299 3058.967918 2991.713226 3392.205633 2913.538678 3349.242187 2878.149241 2171.606919 2963.282847 3294.022913 0.926070152 0.928641967 0.908224777 1.029806326 0.884492536 1.016763476 0.873749005 0.659256774 0.899593878 1 11.68563488 -4.324781972 2.853753107 0.959327349 0.626709356 0.754295337 0.049403611 0.112485781 1.36333749 0.006388485 0.079854062 4.73E-05 4.324781972 -0.332617992 SNVSSPATPTASSS(ph)SSTTPTRK ddPTM_HeLa_Curcumin_4h_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 SNVSSPATPT(0.001)AS(0.149)S(0.106)S(0.285)S(0.106)S(0.076)T(0.137)T(0.137)PT(0.001)RK 78.206 0.00045846 49911000 550.01 434.65 420.09 564.42 528.35 498.63 519.22 397.09 643.16 516.68 TRUE FALSE FALSE 506.4761281 472.2192092 435.6589049 562.0845796 522.0497713 395.2085173 533.7879158 518.160913 572.6069571 534.6345915 0.947331385 0.883255997 0.814872273 1.051343457 0.976460894 0.739212396 0.998416347 0.969187032 1.071024895 1 9.062409375 -8.209647379 1.076992038 0.990342564 0.920001856 0.167109143 0.090227403 0.749420478 1.807839927 0.024764783 0.017829671 6.17E-09 8.209647379 -0.070340708 SNVSSPATPTASSSS(ph)STTPTRK ddPTM_HeLa_Curcumin_4h_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 SNVSSPAT(0.007)PT(0.084)AS(0.128)S(0.039)S(0.029)S(0.175)S(0.175)T(0.175)T(0.175)PT(0.012)RK 80.355 0.00039587 45513000 3247.4 2456.5 2543.6 2809.8 2676.5 3497.2 2944.5 1062.7 3332.2 2798.9 TRUE FALSE FALSE 2990.364863 2668.828914 2637.868054 2798.173792 2644.584486 2771.841298 3027.114745 1386.712338 2966.665997 2896.161567 1.032526948 0.921505535 0.910815227 0.96616633 0.913134307 0.957074125 1.045216116 0.478810421 1.024344094 1 11.49992637 -4.257666588 24.99962693 0.989931928 0.478810225 0.898879248 0.049638887 88.87461122 588884.629 0.007770579 0.077752486 5.53E-05 4.257666588 -0.511121702 SNVSSPATPTASSSSS(ph)TTPTRK ddPTM_HeLa_Curcumin_4h_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 SNVSSPAT(0.003)PT(0.036)AS(0.018)S(0.021)S(0.016)S(0.016)S(0.48)T(0.355)T(0.056)PTRK 105.17 2.13E-05 9748300 2514.3 1911.8 1654.9 1883.2 1979.1 2371.7 1715.2 875.45 1948.5 2151.9 TRUE FALSE FALSE 2315.290502 2077.047473 1716.23205 1875.407817 1955.500525 1879.782685 1763.323896 1142.370675 1734.754425 2226.678365 1.039795661 0.932800851 0.770758847 0.842244595 0.878214185 0.844209346 0.791907769 0.513038027 0.779077236 1 11.12067747 -3.374949375 0.303346959 1.029263738 1.38E-15 0.403428612 0.107394195 4.927950528 0.217854575 0.033847867 2.079257285 0.000421746 3.374949375 -1.029263738 SNVSSPATPTASSSSSTT(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 2 SNVSSPATPTASSSSSTTPTR 21 0 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 SNVSSPATPTASSSSST(0.211)T(0.787)PT(0.002)R;SNVSSPATPTAS(0.002)S(0.008)S(0.003)S(0.01)S(0.01)T(0.01)T(0.956)PT(0.001)R ; 258.03 1.50E-47 54791000 8856.1 6865.4 7276.7 7146 7556.7 9424.4 6686.3 3623.9 7719.3 7231.3 TRUE FALSE FALSE 8155.13034 7458.814584 7546.380903 7116.431745 7466.591288 7469.673205 6873.899583 4728.810428 6872.512103 7482.587137 1.089881105 0.99682295 1.00852563 0.95106567 0.997862257 0.998274135 0.918652794 0.631975324 0.918467367 1 12.86932146 -3.823679815 1.169779369 1.029157735 3.87E-15 0.814841545 0.050072263 0.957136869 0.535354901 0.006934982 1.539418995 0.000150079 3.823679815 -1.029157735 SNVVSPT(ph)KNEDNGAPENSVEKPHEKPEAR ddPTM_HeLa_Curcumin_4h_R1 2 SNVVSPTKNEDNGAPENSVEKPHEKPEAR 29 3 X6RLN4;Q71RC2-2;Q71RC2-6;Q71RC2-5;Q71RC2-3;Q71RC2;Q71RC2-4 X6RLN4 LARP4 La-related protein 4 1 0 S(0.002)NVVS(0.033)PT(0.964)KNEDNGAPENSVEKPHEKPEAR;S(0.007)NVVS(0.214)PT(0.778)KNEDNGAPENS(0.001)VEKPHEKPEAR ; 53.209 0.0018212 48147000 4009.68 3480.3 3517.21 3656.02 3720.54 3721.86 3331.71 2634.9 3724.96 3791.5 TRUE FALSE FALSE 3692.309597 3781.121624 3647.560897 3640.892358 3676.17499 2949.904282 3425.188816 3438.26888 3316.341207 3923.254343 0.941134394 0.96377173 0.929728378 0.928028631 0.937021837 0.751902381 0.873047862 0.876381845 0.845303648 1 11.93783515 -5.925384521 0.44884499 0.983839652 0.820957723 0.157541536 0.061429927 0.812741625 0.269535981 0.013568877 0.056975047 1.19E-06 5.925384521 -0.162881928 SPAAPYFLGSSFS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 1 SPAAPYFLGSSFSPVR 16 0 P30291 P30291 WEE1 Wee1-like protein kinase 1 0 SPAAPYFLGS(0.018)S(0.122)FS(0.86)PVR 114.01 0.0019111 0 603.12 413 675.2 677.85 749.76 910.75 639.43 381.01 586.15 603.51 TRUE FALSE FALSE 555.3824156 448.6978797 700.223506 675.0452363 740.8196017 721.8501837 657.3706849 497.178195 521.8508115 624.4819276 0.88934906 0.718512194 1.121287062 1.08096841 1.186294701 1.155918453 1.052665667 0.796145049 0.835653985 1 9.286516011 SPAGPAATPAQAQAAS(ph)TPR ddPTM_HeLa_Curcumin_4h_R1 1 SPAGPAATPAQAQAASTPR 19 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 SPAGPAAT(0.002)PAQAQAAS(0.499)T(0.499)PR 77.912 0.0052134 12106000 919.47 637.4 779.84 1028.6 875.49 1001.4 1018 952.62 901.4 723.78 TRUE FALSE FALSE 846.6929793 692.4940158 808.7415564 1024.343926 865.0503536 793.6983519 1046.56234 1243.069453 802.5186752 748.9313011 1.130534908 0.924642908 1.079860803 1.367740838 1.155046334 1.059774576 1.397407664 1.659791026 1.071551789 1 9.548689577 -1 0.54143521 1.060139344 26.5176994 0.716621425 0.112851746 46.77000232 0.400708495 0.022042952 1386.391872 0.1 1 25.45756006 SPAGPAATPAQAQAAST(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 SPAGPAATPAQAQAASTPR 19 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 SPAGPAATPAQAQAAS(0.239)T(0.761)PR;SPAGPAATPAQAQAAS(0.235)T(0.765)PR;SPAGPAAT(0.002)PAQAQAAS(0.248)T(0.75)PR ;; 173.09 8.80E-06 198103000 7055.4 6170.3 6387.9 7055.7 8203.6 9510.7 9483.4 4718 6631.6 5652.3 TRUE FALSE FALSE 6496.957645 6703.633238 6624.641193 7026.505383 8105.777428 7538.073612 9749.478681 6156.496481 5904.130071 5848.717004 1.110834674 1.146171585 1.132665709 1.201375512 1.38590693 1.288842255 1.666943139 1.052623417 1.009474397 1 12.51390447 -6.317004644 0.697708618 1.040462458 1.387350659 0.426812135 0.146393267 0.434081065 0.414827486 0.028592524 0.068879505 4.82E-07 6.317004644 0.346888201 SPALK(ac)SPLQSVVVR ddPTM_HeLa_Curcumin_4h_R1 2 SPALKSPLQSVVVR 14 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 0 1 ; SPALK(1)SPLQSVVVR;SPALK(1)SPLQSVVVR 112.08 0.0012093 7603300 555.67 563.06 669.31 404.71 578.89 574.01 411.44 624.82 592.43 501 FALSE TRUE FALSE 511.6881332 611.7283975 694.1152174 403.0354173 571.9871148 454.9538556 422.9838991 815.3247417 527.4419112 518.4097127 0.987034233 1.180009522 1.338931738 0.777445729 1.103349534 0.877595162 0.815925876 1.572742026 1.017422896 1 9.017948938 -4.24928107 24.8093809 1.005395344 1.572742413 0.525781532 0.160010997 1017.046695 2075272.26 0.021093197 0.476536687 5.63E-05 4.24928107 0.567347069 SPALKSPLQS(ph)VVVR ddPTM_HeLa_Curcumin_4h_R1 1 SPALKSPLQSVVVR 14 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 SPALKS(0.168)PLQS(0.832)VVVR 130.02 0.010427 61099000 643.53 776.03 783.71 785.96 862.15 1010.7 560.16 1325.2 1117.8 817.43 TRUE FALSE FALSE 592.5939215 843.1065753 812.754982 782.7079058 851.8694243 801.0694271 575.876582 1729.24738 995.1801366 845.8356317 0.700601747 0.996773538 0.960889979 0.925366438 1.007133529 0.947074582 0.680837459 2.044424844 1.176564452 1 9.724233526 -4.255315737 24.9986757 0.883371598 2.044425355 0.835908725 0.146286355 177.8424905 725989.7706 0.018912711 0.233436728 5.56E-05 4.255315737 1.161053757 ILENSEDS(ph)SPECLF ddPTM_HeLa_Curcumin_4h_R1 2 ILENSEDSSPECLF 14 0 A0A087WSW7;F6XU50;A0A0B4J1V9;Q9NRZ9-6;Q9NRZ9-5;Q9NRZ9-3;Q9NRZ9-2;Q9NRZ9 A0A087WSW7 HELLS Lymphoid-specific helicase 1 0 ILENSEDS(0.5)S(0.5)PECLF;ILENSEDS(0.973)S(0.027)PECLF ; 155.39 0.00039416 14429800 5166 4370.2 4278 5221.5 4582 4795.4 3451 1385.53 5213.1 4855.7 TRUE FALSE FALSE 4757.105649 4747.940615 4436.546443 5199.894817 4527.362643 3800.779985 3547.825772 1807.971719 4641.235973 5024.435214 0.946794107 0.944970014 0.882994059 1.034921259 0.901068966 0.756459149 0.706114343 0.359835811 0.923732873 1 12.29474572 -4.187507698 0.861445543 0.970095406 1.50E-12 0.924794512 0.051578682 0.426879128 0.213268712 0.007784764 0.402725789 6.49E-05 4.187507698 -0.970095406 down SPART(ph)PPSEEDSAEAER ddPTM_HeLa_Curcumin_4h_R1 1 SPARTPPSEEDSAEAER 17 1 O43765;K7EMD6 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 0 S(0.032)PART(0.968)PPSEEDSAEAER 110.61 0.00093331 16682000 1029.8 856.66 690.75 1104.6 789.52 1100 560.58 866.96 850.14 849.58 TRUE FALSE FALSE 948.2902434 930.7058732 716.3498026 1100.029458 780.1054897 871.8476004 576.3083661 1131.292113 756.8817689 879.1028418 1.078702284 1.058699653 0.814864619 1.251309182 0.887388201 0.991746994 0.655564217 1.286871182 0.860970677 1 9.779888139 SPASDTYIVFGEAK ddPTM_HeLa_Curcumin_4h_R1 2 SPASDTYIVFGEAK 14 0 F8VZJ2;F8W0W4;H0YHX9;Q13765;E9PAV3-2;E9PAV3;F8W1N5;F8VNW4 F8VZJ2 NACA "Nascent polypeptide-associated complex subunit alpha;Nascent polypeptide-associated complex subunit alpha, muscle-specific form" 0 0 ; ; 180.18 7.54E-08 3402500 2453.29 2054.37 2074.54 2147.97 2103.32 2767.65 2106.48 2113.31 2541.5 2076.88 FALSE FALSE TRUE 2259.109508 2231.940589 2151.424277 2139.082269 2078.239283 2193.608192 2165.582159 2757.648491 2262.703809 2149.051425 1.051212401 1.038570116 1.001104139 0.995361137 0.967049582 1.020733225 1.007692107 1.283193347 1.052884906 1 11.06948429 -4.26018629 24.97515618 1.017269537 1.283193433 0.90821289 0.025572625 24.51089098 488465.0897 0.00391865 0.032632673 5.49E-05 4.26018629 0.265923897 SPAVATSTAAPPPPS(ph)SPLPSK ddPTM_HeLa_Curcumin_4h_R1 1 SPAVATSTAAPPPPSSPLPSK 21 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 0 SPAVATSTAAPPPPS(0.618)S(0.382)PLPSK 221.81 5.25E-23 353240000 3064.2 2595 2851.5 2759.6 2334.4 2031.9 1606.8 1776.7 3018.2 2527.6 TRUE FALSE FALSE 2821.665337 2819.300237 2957.179098 2748.181506 2306.563805 1610.461036 1651.882484 2318.407651 2687.111011 2615.433912 1.078851706 1.07794742 1.130664814 1.050755477 0.881904832 0.615752908 0.631590221 0.886433276 1.027405433 1 11.3528346 -5.541672065 3.381744016 1.049778982 0.705007498 0.806993907 0.076678328 0.075737929 1.813629902 0.011416391 0.025323163 2.87E-06 5.541672065 -0.344771484 SPAVATSTAAPPPPSS(ph)PLPSK ddPTM_HeLa_Curcumin_4h_R1 3 SPAVATSTAAPPPPSSPLPSK 21 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 0 SPAVATSTAAPPPPS(0.234)S(0.766)PLPSK;SPAVATSTAAPPPPS(0.216)S(0.777)PLPS(0.007)K;SPAVATSTAAPPPPS(0.408)S(0.592)PLPSK ;; 171.52 1.14E-08 793680000 22490.5 18328.9 20264.1 19965.3 18444.5 16573.9 10784.1 12804 22886.6 20338.1 TRUE FALSE FALSE 20710.35319 19913.16844 21015.10537 19882.68888 18224.56138 13136.28631 11086.67282 16707.88066 20375.99724 21044.84746 0.984105645 0.946225364 0.998586728 0.944777049 0.865986861 0.624204397 0.526811745 0.793917879 0.968217863 1 14.36117943 -5.449977771 2.488168852 0.986293912 0.633945309 0.832777421 0.064822479 0.071074383 0.859558289 0.008764466 0.02192162 3.55E-06 5.449977771 -0.352348604 SPDASSAFSPAS(ph)PATPNGTK ddPTM_HeLa_Curcumin_4h_R1 1 SPDASSAFSPASPATPNGTK 20 0 Q53GS7-2;Q53GS7 Q53GS7-2 GLE1 Nucleoporin GLE1 1 0 SPDASSAFS(0.005)PAS(0.989)PAT(0.006)PNGTK 142.94 1.03E-06 0 1192 846.91 985.86 920.88 966.75 1430.6 656.68 439.29 1240.6 1020.9 TRUE FALSE FALSE 1097.651942 920.1131266 1022.396839 917.0696426 955.2221377 1133.877434 675.1046734 573.2274988 1104.509284 1056.376199 1.039072958 0.871008953 0.967834035 0.868127892 0.904244282 1.073365185 0.639075998 0.542635757 1.04556434 1 10.04490799 -4.680254014 5.252352447 0.988566585 0.570153595 0.817808922 0.071756013 0.058305406 2.707474935 0.010569015 0.041324158 2.09E-05 4.680254014 -0.41841299 SPDEEDYDYESYEK ddPTM_HeLa_Curcumin_4h_R1 2 SPDEEDYDYESYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 0 ; ; 181.66 0.00091757 65837000 6276.9 5315.2 5838 5345.6 6062.4 6195.3 5150.8 4494.5 5590.2 5330.9 FALSE FALSE TRUE 5780.076742 5774.622204 6054.361416 5323.481324 5990.109839 4910.324945 5295.317585 5864.85236 4976.969046 5516.148378 1.047846495 1.046857664 1.097570442 0.965072177 1.085922537 0.890172745 0.959966488 1.06321512 0.902254382 1 12.42944555 -5.276110944 24.9329037 1.029942414 0.970002944 0.092790818 0.0669963 865.7873414 1471321.62 0.007401435 0.016611587 5.30E-06 5.276110944 -0.059939471 SPEAKPLPGK(ac)LPK ddPTM_HeLa_Curcumin_4h_R1 1 SPEAKPLPGKLPK 13 2 P46087;P46087-4;F5GWB7;F5H709;F5H359;P46087-2;F5H5X6;P46087-3 P46087;P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 0 1 SPEAKPLPGK(1)LPK 79.089 0.008828 6241000 3175.3 3133.3 3265.4 3265 3562.9 4373.5 3435.1 2568 3418.3 2904.6 FALSE TRUE FALSE 2923.971654 3404.12849 3386.418597 3251.490295 3520.414745 3466.3868 3531.479661 3350.971378 3043.321042 3005.534634 0.972862406 1.132619951 1.126727524 1.081834246 1.171310656 1.153334505 1.17499217 1.114933543 1.012572275 1 11.55340593 -7.256816042 24.15169069 0.987185023 1.137517581 0.846768906 0.027498092 58.64652783 306361.4356 0.004613459 0.005548973 5.54E-08 7.256816042 0.150332558 SPEDLER ddPTM_HeLa_Curcumin_4h_R1 1 SPEDLER 7 0 P06744-2;P06744;A0A2U3TZU2;Q8N196 P06744-2 GPI;SIX5 Glucose-6-phosphate isomerase;Homeobox protein SIX5 0 0 102.77 0.018908 11062000 4963.2 3155.3 3752.7 4110.3 4252.7 5082.2 4153 3279.4 4869.1 4354.8 FALSE FALSE TRUE 4570.357483 3428.030072 3891.778363 4093.292668 4201.98933 4028.094432 4269.522003 4279.273963 4334.971912 4506.128976 1.014253588 0.760748325 0.863663331 0.90838338 0.932505339 0.893914589 0.947492188 0.949656343 0.96201683 1 12.13767289 SPEKIEEVLSPEGS(ph)PSKSPSK ddPTM_HeLa_Curcumin_4h_R1 1 SPEKIEEVLSPEGSPSKSPSK 21 2 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 0 SPEKIEEVLSPEGS(0.363)PS(0.217)KS(0.363)PS(0.056)K 108.14 3.67E-05 48948000 1644.1 1150.3 1527.3 1648.7 1496.9 1870 1510.7 1526.9 1651.5 1524.7 TRUE FALSE FALSE 1513.96775 1249.726806 1583.903082 1641.878116 1479.050445 1482.140921 1553.086176 1992.444781 1470.334582 1577.683212 0.959614541 0.792127847 1.003942407 1.04068935 0.937482528 0.939441397 0.984409395 1.262892808 0.931958058 1 10.62359184 -4.262666402 4.911858904 0.967455779 1.277997319 0.67033932 0.064423881 0.080178195 5.779284911 0.008850213 0.084428196 5.46E-05 4.262666402 0.310541541 SPEKIEEVLSPEGSPSKS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 SPEKIEEVLSPEGSPSKSPSK 21 2 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 0 SPEKIEEVLSPEGSPS(0.04)KS(0.861)PS(0.099)K 119.48 9.76E-06 57538000 2102.6 1384.9 1542 1712.1 1391.4 1838.5 1336 1862.6 1928.7 1676.1 TRUE FALSE FALSE 1936.176991 1504.604585 1599.147876 1705.015784 1374.808464 1457.174376 1373.484564 2430.498166 1717.126435 1734.34435 1.11637403 0.867535092 0.922047502 0.983089537 0.792696366 0.840187461 0.791933023 1.401393077 0.990072378 1 10.76017466 -7.261163471 24.99991425 1.054954403 0.927946156 0.051088946 0.169225524 40.79194255 3696198.944 0.026991835 0.031968685 5.48E-08 7.261163471 -0.127008247 SPEKIEEVLSPEGSPSKS(ph)PSKK ddPTM_HeLa_Curcumin_4h_R1 1 SPEKIEEVLSPEGSPSKSPSKK 22 3 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 0 SPEKIEEVLSPEGS(0.007)PS(0.29)KS(0.515)PS(0.188)KK 55.536 0.007064 26457000 2287.6 1276.1 1481.5 1383.9 1249.1 1725.3 1343.4 1547.3 1917 1680.1 TRUE FALSE FALSE 2106.534046 1386.400398 1536.405693 1378.173788 1234.205298 1367.453332 1381.092188 2019.064647 1706.709896 1738.48335 1.211707921 0.797476949 0.883762098 0.792744888 0.709932194 0.786578331 0.794423593 1.161394296 0.981723464 1 10.76361353 -7.25152307 24.84258333 1.099973186 0.836399152 0.361630711 0.129609408 417.6613279 1046336.155 0.022365931 0.027213672 5.60E-08 7.25152307 -0.263574034 SPENTEGK(ac)DGSK ddPTM_HeLa_Curcumin_4h_R1 1 SPENTEGKDGSK 12 1 Q15651;A0A087WZE9;Q15651-2 Q15651 HMGN3 High mobility group nucleosome-binding domain-containing protein 3 0 1 SPENTEGK(1)DGSK 118.87 0.0011517 635390 207.98 227.96 251.77 299.1 348.25 358.37 357.42 298.08 326.31 366.07 FALSE TRUE FALSE 191.5181635 247.6638466 261.1008177 297.8624035 344.0973462 284.0400223 367.4482433 388.9632198 290.5146094 378.7909053 0.505603912 0.653827331 0.689300651 0.786350462 0.908409736 0.749859668 0.970055612 1.026854696 0.766952441 1 8.565257882 -4.468762123 0.922381533 0.750294108 1.140922343 0.365643107 0.127406969 2.059831674 1.616910629 0.030404353 0.745242405 3.40E-05 4.468762123 0.390628235 SPFEVSVDK ddPTM_HeLa_Curcumin_4h_R1 2 SPFEVSVDK 9 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 102.62 0.0069106 5736200 3540.3 2773.3 3086.7 3356.6 4208.6 3943.8 3110.2 2768.1 3204.8 2801.3 FALSE FALSE TRUE 3260.081519 3013.011694 3201.095817 3342.711279 4158.415194 3125.811424 3197.463841 3612.080947 2853.241458 2898.644966 1.124691557 1.039455238 1.104342151 1.153197897 1.434606598 1.07836988 1.10308916 1.246127411 0.984336299 1 11.50116292 -6.282187934 3.12588741 1.060060703 1.205722265 0.383854517 0.09838535 0.238130201 4.756337434 0.015548637 0.02552153 5.22E-07 6.282187934 0.145661562 ELS(ph)LDDPEVEQVSGR ddPTM_HeLa_Curcumin_4h_R1 2 ELSLDDPEVEQVSGR 15 0 L7N2F4;C9J5N1;Q9BTE6;Q9BTE6-2;Q9BTE6-3 L7N2F4 AARSD1;PTGES3L-AARSD1 Alanyl-tRNA editing protein Aarsd1 1 0 ELS(1)LDDPEVEQVSGR;ELS(1)LDDPEVEQVSGR ; 163.91 0.00025991 14197400 4167.4 3136.1 3529.1 3353.2 4025.8 7246.2 7488.3 16419.9 4244.8 3904.4 TRUE FALSE FALSE 3837.545893 3407.17051 3659.891551 3339.325347 3977.794964 5743.256438 7698.401544 21426.25192 3779.15606 4040.077609 0.94986935 0.843342836 0.905896348 0.826549802 0.9845838 1.42157082 1.905508331 5.303425823 0.935416699 1 11.98016729 -3.906938364 1.392417844 0.952724264 11.23300557 0.990812059 0.125017695 0.184419733 0.163960175 0.018399598 3.368290635 0.000123897 3.906938364 10.28028131 up SPFSVAVSPSLDLSK ddPTM_HeLa_Curcumin_4h_R1 1 SPFSVAVSPSLDLSK 15 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 108.37 0.0030545 0 0 0 0 0 0 79.585 0 76.327 0 0 FALSE FALSE TRUE 0 0 0 0 0 63.07817389 0 99.59875093 0 0 0 TAPAAPAEDAVAAAAAAPSEPSEPS(ph)RPSPQPKPR ddPTM_HeLa_Curcumin_4h_R1 2 TAPAAPAEDAVAAAAAAPSEPSEPSRPSPQPKPR 34 2 Q53GA4 Q53GA4 PHLDA2 Pleckstrin homology-like domain family A member 2 1 0 TAPAAPAEDAVAAAAAAPS(0.007)EPS(0.159)EPS(0.417)RPS(0.417)PQPKPR;TAPAAPAEDAVAAAAAAPS(0.028)EPS(0.044)EPS(0.464)RPS(0.464)PQPKPR ; 94.957 2.99E-11 409319000 7630.9 6472.3 8006.7 7249.7 7172.1 7856.4 5413.7 1954.26 7935.6 7090.2 TRUE FALSE FALSE 7026.906213 7031.736772 8303.435345 7219.702662 7086.577392 6226.89408 5565.593852 2550.104878 7065.084534 7336.583922 0.957789932 0.958448352 1.131784961 0.984068708 0.965923305 0.848745703 0.758608354 0.347587502 0.96299376 1 12.84089275 -4.186301207 1.183060911 0.989259683 5.75E-19 0.930577243 0.053541558 0.32120841 0.327849661 0.008017578 0.406338466 6.51E-05 4.186301207 -0.989259683 down SPGGGGGGGSGNDNNQAATKS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 SPGGGGGGGSGNDNNQAATKSPR 23 1 Q9NS37;E9PIM0;J3KN20 Q9NS37 CREBZF CREB/ATF bZIP transcription factor 1 0 SPGGGGGGGSGNDNNQAAT(0.368)KS(0.632)PR;SPGGGGGGGSGNDNNQAAT(0.404)KS(0.596)PR ; 99.171 3.25E-05 3533300 1515.77 1031.74 1319.47 1320.22 1778.1 1876.69 1214.61 753.65 1488.87 1424.1 TRUE FALSE FALSE 1395.795205 1120.919008 1368.370719 1314.757279 1756.897319 1487.443339 1248.688688 983.4344156 1325.544686 1473.587369 0.947208991 0.7606736 0.928598295 0.892215356 1.192258671 1.009402883 0.847380151 0.667374352 0.899535863 1 10.52511689 -4.422159306 2.948448832 0.966979924 0.660906608 0.408705563 0.104503048 0.217537747 3.097447562 0.014631399 0.127687761 3.78E-05 4.422159306 -0.306073316 SPGKAEAES(ph)DALPDDTVIESEALPSDIAAEAR ddPTM_HeLa_Curcumin_4h_R1 1 SPGKAEAESDALPDDTVIESEALPSDIAAEAR 32 1 Q9GZR7-2;Q9GZR7;G3V529;A0A1W2PRR2;F5GYL3 Q9GZR7-2 DDX24 ATP-dependent RNA helicase DDX24 1 0 S(0.007)PGKAEAES(0.903)DALPDDT(0.086)VIES(0.003)EALPS(0.001)DIAAEAR 42.288 0.012875 4190500 869.38 906.93 759.76 1074 700.43 1658.4 1180.3 857.31 1519.1 1143.3 TRUE FALSE FALSE 800.5676556 985.320988 787.917374 1069.556073 692.0778297 1314.429146 1213.416041 1118.699872 1352.458531 1183.02959 0.676709748 0.832879411 0.666016624 0.904082266 0.585004666 1.111070388 1.025685284 0.945622901 1.143216148 1 10.20827044 -5.230256776 24.98279448 0.81822502 1.02728211 0.239734881 0.160475735 673.541144 539625.0794 0.021098237 0.053783712 5.88E-06 5.230256776 0.20905709 SPGLVPPS(ph)PEFAPR ddPTM_HeLa_Curcumin_4h_R1 2 SPGLVPPSPEFAPR 14 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 0 S(0.284)PGLVPPS(0.716)PEFAPR;S(0.001)PGLVPPS(0.999)PEFAPR ; 150.12 0.00050942 15648100 4569.8 3863.9 4277.1 5024.1 5357.3 5442.1 4330.1 5281.1 4958.7 3966.4 TRUE FALSE FALSE 4208.095508 4197.878299 4435.613089 5003.311605 5293.417696 4313.347115 4451.590952 6891.283079 4414.743016 4104.232105 1.025306416 1.022816983 1.080741287 1.219061563 1.289746184 1.050951068 1.084634309 1.679067583 1.075656275 1 12.00289661 -2.114386673 1.323938296 1.049317406 199.9999655 0.74354763 0.099076079 180.7160418 1.278225239 0.01639746 108203.3599 0.00768446 2.114386673 198.9506481 SPGS(ph)NSKVPEIEVTVEGPNNNNPQTSAVR ddPTM_HeLa_Curcumin_4h_R1 1 SPGSNSKVPEIEVTVEGPNNNNPQTSAVR 29 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 0 S(0.292)PGS(0.305)NS(0.305)KVPEIEVT(0.097)VEGPNNNNPQTSAVR 48.321 0.0089409 131000000 1217.1 800.7 863.11 878.34 578.04 1370.5 506.27 709.18 1642.3 1157.6 TRUE FALSE FALSE 1120.765251 869.9089402 895.0976159 874.7056618 571.1472505 1086.242851 520.4745736 925.4057173 1462.143799 1197.826514 0.935665756 0.72623951 0.747268161 0.730244031 0.476819676 0.906844888 0.434515823 0.772570741 1.220664079 1 10.22620326 -7.148148454 1.071228411 0.983354815 0.654613944 0.546017437 0.150421238 0.23211476 0.519478213 0.024145589 0.030329748 7.11E-08 7.148148454 -0.328740871 SPGS(ph)PPGPELPIETALDDR ddPTM_HeLa_Curcumin_4h_R1 2 SPGSPPGPELPIETALDDR 19 0 F5GZI3;B1AP52;Q5VWV2;Q8TEW0-4;Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-3;Q8TEW0-7;Q8TEW0-6;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 F5GZI3;Q5VWV2 PARD3 Partitioning defective 3 homolog 1 0 S(0.008)PGS(0.992)PPGPELPIETALDDR;S(0.003)PGS(0.997)PPGPELPIETALDDR ; 179.09 3.58E-07 8723500 1146.88 1150.99 1221.35 1261.51 1224.19 1294.63 1051.24 740.38 1353.69 986.78 TRUE FALSE FALSE 1056.103238 1250.476447 1266.614305 1256.290206 1209.592334 1026.109145 1080.734965 966.1184537 1205.193594 1021.070532 1.034309781 1.224671958 1.2404768 1.230365746 1.184631518 1.004934638 1.058433215 0.946181898 1.180323549 1 9.99586681 -7.446740029 8.873980259 1.015061771 1.130422013 0 0.107860011 0.450179345 49.50893221 0.017540264 0.019988598 3.57E-08 7.446740029 0.115360242 SPGS(ph)PPGPELPIETALDDRER ddPTM_HeLa_Curcumin_4h_R1 1 SPGSPPGPELPIETALDDRER 21 1 F5GZI3;B1AP52;Q5VWV2;Q8TEW0-4;Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-3;Q8TEW0-7;Q8TEW0-6;Q8TEW0-8;Q8TEW0-5;Q5VWU8;Q8TEW0-9;Q8TEW0-10 F5GZI3;Q5VWV2 PARD3 Partitioning defective 3 homolog 1 0 S(0.128)PGS(0.871)PPGPELPIET(0.001)ALDDRER 75.184 0.00088721 3232500 521.69 530 783.85 801.04 826.75 953.19 695.96 560.6 898.52 690.49 TRUE FALSE FALSE 480.397686 575.8108384 812.9001705 797.7255087 816.8915462 755.4876493 715.4867645 731.5243593 799.954604 714.4844761 0.672369662 0.805910916 1.137743643 1.116505026 1.143330014 1.057388473 1.001402813 1.0238492 1.119624891 1 9.480758855 -6.765140463 24.99978101 0.838009655 1.079967456 0.292730035 0.123504803 66.17385429 446986.7019 0.021037732 0.028253478 1.72E-07 6.765140463 0.241957802 IRAFPMT(ph)MDEKYVNSIWDLLK ddPTM_HeLa_Curcumin_4h_R1 1 IRAFPMTMDEKYVNSIWDLLK 21 2 Q13618 Q13618 CUL3 Cullin-3 1 0 IRAFPMT(0.998)MDEKY(0.002)VNSIWDLLK 41.912 0.0092025 0 148.77 240.9 186.56 107.27 178.9 530.82 403.77 631.36 304.36 245.64 TRUE FALSE FALSE 136.9946975 261.7223226 193.4740777 106.8261452 176.7667343 420.7219484 415.0986995 823.8587576 270.9724695 254.1759717 0.538975799 1.029689474 0.761181619 0.420284201 0.695450216 1.655238871 1.633115423 3.241292841 1.066082162 1 7.989683843 -3.904771471 0.937866814 0.764439486 6.178481941 0.881030061 0.270284504 0.846242084 0.359294794 0.042844227 5.44886629 0.000124517 3.904771471 5.414042456 up ESYDAPPTPS(ph)GAR ddPTM_HeLa_Curcumin_4h_R1 1 ESYDAPPTPSGAR 13 0 Q96S55-2;Q96S55 Q96S55-2 WRNIP1 ATPase WRNIP1 1 0 ESYDAPPT(0.391)PS(0.609)GAR 143.56 0.00083658 45563000 2038.2 1997.2 1659.7 1900.9 2082 3216.3 3222.6 4129.2 2222.1 1852.4 TRUE FALSE FALSE 1876.874319 2169.829069 1721.209942 1893.034579 2057.17351 2549.203125 3313.017483 5388.174072 1978.341189 1916.770762 0.979185595 1.132023251 0.897973809 0.987616577 1.073249629 1.329946791 1.728436988 2.811068584 1.032121957 1 10.90446209 -3.90360771 0.991860394 0.991410815 5.085033216 0.987603058 0.061703957 0.230090989 0.108382226 0.008840636 1.186048408 0.000124851 3.90360771 4.093622402 up RALSS(ph)DSILS(ph)PAPDAR ddPTM_HeLa_Curcumin_4h_R1 2 RALSSDSILSPAPDAR 16 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 2 0 RALS(0.176)S(0.433)DS(0.392)ILS(0.998)PAPDAR;RALS(0.236)S(0.717)DS(0.046)ILS(1)PAPDAR ; 152.66 0.00032235 9478800 4200.9 3467.3 3209.9 4171.4 3504.2 7294.3 8156.1 14915.6 4465.4 3446.5 TRUE FALSE FALSE 3868.394332 3766.997962 3328.861718 4154.139852 3462.414704 5781.379956 8384.938215 19463.29778 3975.556792 3566.265618 1.084718511 1.056286425 0.933430673 1.164843087 0.970879647 1.621129937 2.351181631 5.457613049 1.114767439 1 11.80019844 -3.8935122 1.208276868 1.035576867 11.45547996 0.992577766 0.114212784 0.161383666 0.107958486 0.015469409 2.604730969 0.000127787 3.8935122 10.4199031 up VAAETQS(ph)PSLFGSTK ddPTM_HeLa_Curcumin_4h_R1 1 VAAETQSPSLFGSTK 15 0 Q9UKX7;Q9UKX7-2 Q9UKX7 NUP50 Nuclear pore complex protein Nup50 1 0 VAAET(0.002)QS(0.826)PS(0.172)LFGSTK 190.82 2.57E-06 25585000 1446.2 1382.2 1226.8 1436.4 1914 2548.9 2756.9 7426.4 1375.4 1189.1 TRUE FALSE FALSE 1331.731744 1501.671209 1272.266287 1430.456557 1891.1768 2020.229408 2834.251194 9690.675173 1224.522061 1230.421136 1.082338156 1.220453034 1.034008804 1.16257476 1.537015859 1.641900767 2.303480581 7.875901092 0.995205645 1 10.26493648 -3.888839089 1.478329281 1.097657468 17.90649688 0.987490364 0.223839911 0.228508433 0.217656033 0.033879563 7.364097339 0.00012917 3.888839089 16.80883941 up SPGSNS(ph)KVPEIEVTVEGPNNNNPQTSAVR ddPTM_HeLa_Curcumin_4h_R1 1 SPGSNSKVPEIEVTVEGPNNNNPQTSAVR 29 1 A0A494C1K3;P78347-2;P78347-4;P78347-3;P78347 A0A494C1K3 GTF2I General transcription factor II-I 1 0 S(0.167)PGS(0.167)NS(0.416)KVPEIEVT(0.249)VEGPNNNNPQTSAVR 47.376 0.01014 32102000 1219.5 880.88 809.03 977.51 688.87 1162.3 803.44 859.8 1391.7 1410.1 TRUE FALSE FALSE 1122.975288 957.0193421 839.0133635 973.4653226 680.6556752 921.2258782 825.9823641 1121.949062 1239.033992 1459.10087 0.76963513 0.655896629 0.57502081 0.667167941 0.466489801 0.631365451 0.566089967 0.768931802 0.849176378 1 10.51086391 -8.025092192 0.621014427 0.982289869 0.597910123 0.65292304 0.086867451 0.211482025 0.185250766 0.033352648 0.021651603 9.44E-09 8.025092192 -0.384379746 SPGST(ph)PTTPTSSQAPQK ddPTM_HeLa_Curcumin_4h_R1 1 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 0 SPGS(0.085)T(0.914)PT(0.001)TPTSSQAPQK 228.11 1.33E-21 27396000 4231.5 3515.6 4118.1 3784.1 4297.5 5380.8 4904.7 3207.7 4078 3602.9 TRUE FALSE FALSE 3896.57231 3819.472799 4270.720409 3768.442397 4246.255119 4264.761426 5042.312682 4185.712964 3630.653603 3728.100507 1.045189716 1.024509074 1.145548625 1.010821031 1.138986224 1.143950228 1.352515221 1.122746813 0.973861514 1 11.86422504 -5.486910756 0.79141955 1.022997861 1.250685582 0.548170942 0.071200294 0.408868983 0.422608077 0.011274298 0.057050817 3.26E-06 5.486910756 0.227687721 TAVAPSAVNLADPRT(ph)PTAPAVNLAGAR ddPTM_HeLa_Curcumin_4h_R1 2 TAVAPSAVNLADPRTPTAPAVNLAGAR 27 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 TAVAPSAVNLADPRT(0.944)PT(0.056)APAVNLAGAR;TAVAPSAVNLADPRT(0.881)PT(0.119)APAVNLAGAR ; 101.42 7.30E-07 335620000 2104.99 1923.27 1959.07 1733.23 2131.7 3525 3884 7580.1 2118.22 1848.82 TRUE FALSE FALSE 1938.37782 2089.508889 2031.674858 1726.058354 2106.28087 2793.875265 3992.974587 9891.237596 1885.856566 1913.066357 1.013230834 1.09223022 1.061999156 0.902246985 1.100997287 1.460417332 2.087211754 5.170357817 0.98577687 1 10.9016712 -3.883326345 1.289395908 1.01386464 11.1112595 0.993897812 0.096837512 0.158648865 0.117210003 0.014102477 2.671899163 0.00013082 3.883326345 10.09739486 up SPIYPLSDSETS(ph)ACR ddPTM_HeLa_Curcumin_4h_R1 1 SPIYPLSDSETSACR 15 0 E9PRS6;E9PI72;E9PLB6;E9PII1;E9PK36;E9PN93;E9PQU6;E9PME1;E9PMP1;E9PLH6;E9PMJ9;E9PJY5;E9PLR2;E9PM84;P78524 E9PRS6 ST5 Suppression of tumorigenicity 5 protein 1 0 SPIYPLS(0.034)DS(0.398)ET(0.014)S(0.554)ACR 123.76 0.0010404 9002200 729.07 520.4 629.02 719.64 764.08 817.03 651.46 315.93 890.95 722.06 TRUE FALSE FALSE 671.3633402 565.3810571 652.3320345 716.6623204 754.968845 647.5687682 669.7382143 412.2556026 793.215014 747.1515313 0.898563828 0.756715383 0.873092013 0.959192735 1.010462822 0.866716778 0.896388733 0.551769735 1.061652129 1 9.545257058 -4.08877481 2.039812175 0.932152894 0.29756395 0.647384695 0.082688553 0.640068865 1.893833256 0.011568421 0.880917258 8.15E-05 4.08877481 -0.634588944 SPLAQMEEERR ddPTM_HeLa_Curcumin_4h_R1 1 SPLAQMEEERR 11 1 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;A0A0U1RRM2 G3V1Q4 7-Sep Septin-7 0 0 131.12 0.0026329 27120000 1762.2 1400.4 1653.8 1610.6 1681.1 1778.1 1496.6 1275.6 1776.6 1477.9 FALSE FALSE TRUE 1622.720011 1521.444336 1715.091283 1603.935764 1661.05398 1409.302017 1538.590568 1664.524568 1581.711425 1529.256915 1.061116673 0.994891258 1.12151939 1.048833422 1.08618373 0.921560009 1.006103391 1.08845319 1.034300652 1 10.57861508 -4.244736896 22.83104917 1.030172694 1.08845334 0.099536648 0.052283331 1817.81029 2484674.327 0.007244774 0.228569111 5.69E-05 4.244736896 0.058280646 SPLDPMT(ph)SPGSGLILQANFVHSQR ddPTM_HeLa_Curcumin_4h_R1 1 SPLDPMTSPGSGLILQANFVHSQR 24 0 A0A1B0GW84;A0A087WSZ7;Q08499-2;Q08499-10;Q08499-9;Q08499-11;Q08499;A0A1W2PQN6;Q08499-6;Q08499-7;Q08499-12 A0A1B0GW84;Q08499-6 PDE4D "cAMP-specific 3,5-cyclic phosphodiesterase 4D" 1 0 S(0.082)PLDPMT(0.433)S(0.433)PGS(0.053)GLILQANFVHSQR 60.33 0.0054474 35203000 1357.7 1103.1 1016.6 995.28 1023.3 2171.4 1347.5 1322.4 1563.2 1221.1 TRUE FALSE FALSE 1250.236612 1198.447049 1054.27609 991.1617951 1011.097816 1721.027163 1385.307223 1725.593672 1391.720871 1263.533134 0.989476713 0.948488818 0.834387371 0.784436726 0.800214722 1.362075213 1.096375858 1.365689293 1.101451821 1 10.30324778 -5.256144897 24.98099946 0.951547628 1.256879701 0.645063713 0.118105144 232.5731237 1097347.368 0.016593546 0.040967105 5.54E-06 5.256144897 0.305332073 SPLDPMTS(ph)PGSGLILQANFVHSQR ddPTM_HeLa_Curcumin_4h_R1 2 SPLDPMTSPGSGLILQANFVHSQR 24 0 A0A1B0GW84;A0A087WSZ7;Q08499-2;Q08499-10;Q08499-9;Q08499-11;Q08499;A0A1W2PQN6;Q08499-6;Q08499-7;Q08499-12 A0A1B0GW84;Q08499-6 PDE4D "cAMP-specific 3,5-cyclic phosphodiesterase 4D" 1 0 S(0.037)PLDPMT(0.316)S(0.64)PGS(0.007)GLILQANFVHSQR;S(0.025)PLDPMT(0.112)S(0.453)PGS(0.411)GLILQANFVHSQR ; 87.671 5.04E-05 35979800 2201.8 2016.08 1862.26 2053.05 2035.59 3754.73 2521.68 1813.21 2832.1 2090.35 TRUE FALSE FALSE 2027.525207 2190.340972 1931.276994 2044.555023 2011.316919 2975.956673 2592.431554 2366.049382 2521.425716 2162.989507 0.937371726 1.012645214 0.892873954 0.945245003 0.92987826 1.375853495 1.198540976 1.09387927 1.165713337 1 11.07881095 -5.279432336 24.99867528 0.962795812 1.220336225 0.558853617 0.096241218 287.1828623 398999.6717 0.01002668 0.022460117 5.25E-06 5.279432336 0.257540413 SPLELGEKLS(ph)PLPGGPGAGDPR ddPTM_HeLa_Curcumin_4h_R1 2 SPLELGEKLSPLPGGPGAGDPR 22 1 Q15742-2;Q15742-3;Q15742 Q15742-2 NAB2 NGFI-A-binding protein 2 1 0 S(0.003)PLELGEKLS(0.997)PLPGGPGAGDPR;S(0.001)PLELGEKLS(0.999)PLPGGPGAGDPR ; 69.47 0.001114 92431000 2576.9 2205.33 2499.4 2636.3 2688.9 3371.1 3218.1 2682.4 2744.5 2620.9 TRUE FALSE FALSE 2372.935646 2395.948898 2592.029963 2625.391689 2656.836624 2671.89586 3308.391225 3500.251412 2443.435216 2711.97608 0.874983988 0.883469775 0.955771691 0.968073321 0.979668163 0.985221027 1.219919029 1.290664559 0.900979634 1 11.40512874 -4.728966072 2.288962356 0.940567442 1.295022492 0.911203816 0.039434112 0.085556607 0.842243019 0.007556002 0.041242761 1.87E-05 4.728966072 0.354455049 SPLLAGGS(ph)PPQPVVPAHK ddPTM_HeLa_Curcumin_4h_R1 2 SPLLAGGSPPQPVVPAHK 18 0 Q8NFH5-2;Q8NFH5;C9IYQ7;F8WCF5;F8WEL4;C9JIY9 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 0 SPLLAGGS(1)PPQPVVPAHK;S(0.002)PLLAGGS(0.998)PPQPVVPAHK ; 136.43 0.00028669 221094000 8065.9 6348.4 7241.3 7014.9 7524.7 8212.8 4387.3 3215.38 6740.7 6650 TRUE FALSE FALSE 7427.475504 6897.127408 7509.668948 6985.874203 7434.972867 6509.372703 4510.39583 4195.73456 6001.262074 6881.087005 1.079404387 1.002331086 1.091349222 1.015228291 1.080493948 0.945980293 0.655477227 0.609748802 0.872138671 1 12.74842077 -4.806514188 2.999930841 1.040217297 0.612595619 0.858733723 0.061719566 0.03455562 0.617981207 0.005081964 0.020548686 1.56E-05 4.806514188 -0.427621678 SPLRY(ph)TSILT(ph)NT(ph)QVMK ddPTM_HeLa_Curcumin_4h_R1 1 SPLRYTSILTNTQVMK 16 1 Q9H340 Q9H340 OR51B6 Olfactory receptor 51B6 3 0 S(0.076)PLRY(0.786)T(0.129)S(0.02)ILT(0.991)NT(0.997)QVMK 52.008 0.017031 121760000 2824.6 2564.9 2697.2 3092.7 2663.2 3362.9 2758.5 2571.8 3214.1 2708.2 TRUE FALSE FALSE 2601.029929 2786.598527 2797.160605 3079.903227 2631.443079 2665.396632 2835.896086 3355.929981 2861.521271 2802.309748 0.928173601 0.994393474 0.998162536 1.099058813 0.939026487 0.951142761 1.011985234 1.197558544 1.021129542 1 11.45240072 -4.273313542 3.33444818 0.976521282 1.22426389 0.612024162 0.047743867 0.147538445 2.703228512 0.006941745 0.091779126 5.33E-05 4.273313542 0.247742608 SPLS(ph)PTETFSWPDVR ddPTM_HeLa_Curcumin_4h_R1 1 SPLSPTETFSWPDVR 15 0 A1L390-3;A1L390;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 0 SPLS(0.886)PT(0.113)ETFSWPDVR 132.65 0.00067319 14627000 1045.6 1006.4 937.64 970.02 933.52 1189.1 1029.4 688.79 1050.1 1159 TRUE FALSE FALSE 962.8396567 1093.388732 972.3897632 966.0063143 922.3883837 942.4672561 1058.282194 898.7989002 934.9066572 1199.275164 0.802851327 0.911707975 0.810814559 0.805491803 0.769121559 0.785864066 0.882434845 0.749451775 0.779559759 1 10.227947 -10.1482054 0.369308355 1.147862634 0.802123406 0 0.083287407 1.987750265 0.215126376 0.297929968 0.015496354 7.11E-11 10.1482054 -0.345739228 SPLTILQDDNS(ph)PGTLTLR ddPTM_HeLa_Curcumin_4h_R1 2 SPLTILQDDNSPGTLTLR 18 0 Q99618;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 1 0 SPLTILQDDNS(0.998)PGT(0.002)LTLR;SPLTILQDDNS(0.932)PGT(0.051)LT(0.016)LR ; 121.51 0.00033198 15335300 974.15 781.48 980.5 1234.69 1031.83 1887.29 1488.4 800.97 1243.22 1080.68 TRUE FALSE FALSE 897.0449996 849.027649 1016.838193 1229.58118 1019.526101 1495.84478 1530.160498 1045.182066 1106.841876 1118.23355 0.802198253 0.759257893 0.90932542 1.099574575 0.91172913 1.337685478 1.368372912 0.934672427 0.989812796 1 10.12700582 -5.605467739 1.599033335 0.896266456 1.218116966 0.404691206 0.149580501 0.267194082 1.359041849 0.02335071 0.062379597 2.48E-06 5.605467739 0.32185051 SPMFPALGEAS(ph)SDDDLFQSAKPKPAK ddPTM_HeLa_Curcumin_4h_R1 1 SPMFPALGEASSDDDLFQSAKPKPAK 26 2 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1-5;Q5SRD0;Q641Q2;F8W7U3;E7ESD2;Q641Q2-2;A0A087WYF6 A0A0A0MR88;Q641Q2 FAM21C;FAM21D;FAM21A WASH complex subunit FAM21C;Putative WASH complex subunit FAM21;WASH complex subunit FAM21A 1 0 SPMFPALGEAS(0.533)S(0.464)DDDLFQS(0.003)AKPKPAK 70.917 0.00015733 17868000 2072 1880.3 2114.8 2142.8 2293.3 2581.6 2199.1 803.03 1861.6 1986.2 TRUE FALSE FALSE 1907.999014 2042.824754 2193.176348 2133.933661 2265.953895 2046.147059 2260.800827 1047.87015 1657.387137 2055.220302 0.92836715 0.993968749 1.0671247 1.038299232 1.102535769 0.99558527 1.100028462 0.509857824 0.806427971 1 11.00507733 -4.253948753 24.99720369 0.99667915 0.509857593 0.759168044 0.083344551 278.9941796 931017.6989 0.00935568 0.132505748 5.57E-05 4.253948753 -0.486821557 SPPLIGSESAYESFLS(ph)ADDKASGR ddPTM_HeLa_Curcumin_4h_R1 2 SPPLIGSESAYESFLSADDKASGR 24 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 SPPLIGS(0.002)ES(0.002)AY(0.004)ES(0.005)FLS(0.978)ADDKAS(0.008)GR;SPPLIGS(0.01)ES(0.01)AY(0.043)ES(0.039)FLS(0.893)ADDKAS(0.006)GR ; 60.797 0.0023536 12489900 2109.89 2249.45 1816.42 2075.9 1903.12 1895.48 1799.24 1750.02 2112 1835.32 TRUE FALSE FALSE 1942.88998 2443.882435 1883.738123 2067.310476 1880.426537 1502.336082 1849.721832 2283.593042 1880.318884 1899.097233 1.023059771 1.286865355 0.991912415 1.088575371 0.990168646 0.791079074 0.974000593 1.202462413 0.99011196 1 10.89109806 -5.540396104 23.03884181 1.037493161 0.971489564 0.049563895 0.125153998 234.2336569 308062.9609 0.01804188 0.036093441 2.88E-06 5.540396104 -0.066003597 SPPLLES(ph)PDATR ddPTM_HeLa_Curcumin_4h_R1 1 SPPLLESPDATR 12 0 Q15036-2;Q15036 Q15036-2 SNX17 Sorting nexin-17 1 0 SPPLLES(0.999)PDAT(0.001)R 103.11 0.0076285 20137000 729.06 802.9 784.86 759.46 1030.3 1145.2 554.51 759.71 1008.9 852.8 TRUE FALSE FALSE 671.3541317 872.2990983 813.947602 756.3175558 1018.014345 907.6726109 570.0680582 991.3420817 898.2261941 882.4347365 0.760797489 0.988514008 0.922388442 0.857080444 1.153642647 1.028600273 0.646017246 1.123416884 1.017895326 1 9.785345773 SPPLS(ph)PVGTTPVK ddPTM_HeLa_Curcumin_4h_R1 1 SPPLSPVGTTPVK 13 0 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 0 S(0.084)PPLS(0.912)PVGT(0.004)TPVK 156.2 0.00036589 20662000 2185.5 1953.1 1973.7 1857.8 1930.5 1929.2 1640.2 4462.2 2363.9 1621.7 TRUE FALSE FALSE 2012.515369 2121.917261 2046.847058 1850.112916 1907.480048 1529.062173 1686.219598 5822.704239 2104.586084 1678.053954 1.199315054 1.264510748 1.219774283 1.102534821 1.136721524 0.911211567 1.004866139 3.469914792 1.254182608 1 10.71257339 -4.26000791 24.99980574 1.102354668 3.469915565 0.974417456 0.114119417 13.73245915 239804.8677 0.016766678 0.140832224 5.50E-05 4.26000791 2.367560898 SPPREGS(ph)QGELTPANSQSR ddPTM_HeLa_Curcumin_4h_R1 4 SPPREGSQGELTPANSQSR 19 1 J3QQX0;C9JFE4;A0A096LP07;A0A096LPJ3;A8K070;Q13098-5;Q13098;Q13098-7 J3QQX0 GPS1 COP9 signalosome complex subunit 1 1 0 S(0.035)PPREGS(0.964)QGELT(0.001)PANSQSR;S(0.007)PPREGS(0.992)QGELT(0.001)PANSQSR;S(0.002)PPREGS(0.998)QGELTPANSQSR;SPPREGS(0.999)QGELTPANSQSR ;;; 81.65 0.0017884 135693000 4155.34 3341.86 3483.37 3788.33 3178.39 4114.43 3322.26 3094.16 4283.52 4033.04 TRUE FALSE FALSE 3826.440454 3630.715487 3612.466756 3772.654894 3140.489775 3261.050839 3415.473674 4037.55514 3813.628573 4173.18784 0.916910669 0.87001008 0.865637229 0.904022306 0.75253976 0.781429201 0.818432768 0.967499019 0.913840622 1 12.02693414 -7.726565016 0.558719022 0.992920734 0.832758792 0.3065311 0.061864976 0.423030124 0.312202654 0.0246091 0.019849534 1.88E-08 7.726565016 -0.160161942 SPPREGSQGELTPANS(ph)QSR ddPTM_HeLa_Curcumin_4h_R1 1 SPPREGSQGELTPANSQSR 19 1 J3QQX0;C9JFE4;A0A096LP07;A0A096LPJ3;A8K070;Q13098-5;Q13098;Q13098-7 J3QQX0 GPS1 COP9 signalosome complex subunit 1 1 0 SPPREGS(0.002)QGELT(0.189)PANS(0.658)QS(0.151)R 55.02 0.013449 18698000 1212.8 744.32 822.71 1131.1 964.99 957.32 661.06 691.3 993.93 1133.2 TRUE FALSE FALSE 1116.8056 808.6557042 853.2003563 1126.419808 953.4831245 758.7610408 679.6075644 902.0741876 884.8983657 1172.578616 0.952435585 0.689638796 0.727627423 0.960634786 0.813150702 0.647087565 0.579583795 0.769308067 0.75466016 1 10.19546894 -6.568118839 0.342083342 1.023810477 0.622517184 0.072850001 0.129354292 0.917342699 0.245591216 0.063919991 0.141090006 2.70E-07 6.568118839 -0.401293293 SPPS(ph)SSEIFTPAHEENVR ddPTM_HeLa_Curcumin_4h_R1 1 SPPSSSEIFTPAHEENVR 18 0 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 0 S(0.327)PPS(0.657)S(0.016)SEIFTPAHEENVR 178.56 4.11E-07 95214000 1258.7 1186.5 1343.6 1224.1 1239 1603.5 1123.3 1159.5 1309.9 1094.8 TRUE FALSE FALSE 1159.072567 1289.055773 1393.394998 1219.034999 1224.225734 1270.916025 1154.816775 1513.026212 1166.207247 1132.844219 1.023152652 1.137893235 1.229997007 1.076083524 1.080665562 1.121880665 1.01939592 1.335599536 1.029450677 1 10.14573377 -7.289719312 5.004810061 1.010356198 1.136099966 0.319525672 0.083456014 0.158279278 10.8506023 0.013322689 0.015462186 5.13E-08 7.289719312 0.125743768 SPPST(ph)GSTYGSSQK ddPTM_HeLa_Curcumin_4h_R1 1 SPPSTGSTYGSSQK 14 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 S(0.278)PPS(0.088)T(0.625)GS(0.007)T(0.002)YGSSQK 112.62 0.0074588 12233000 458.33 371.11 372.89 302.49 472.21 387.99 339.21 326.89 304.5 293.49 TRUE FALSE FALSE 422.0526969 403.1870948 386.7096314 301.2383765 466.5792042 307.5165005 348.7273197 426.5572562 271.0971118 303.6887557 1.389754112 1.327632608 1.273374876 0.991931281 1.536372999 1.01260417 1.14830501 1.404586927 0.892680769 1 8.246449682 -9.505667067 1.268617978 1.000702552 1.267009995 0.346521053 0.167270043 0.475425228 1.375200208 0.108431597 0.026520916 3.12E-10 9.505667067 0.266307443 SPPVLGSAAAS(ph)PVHLK ddPTM_HeLa_Curcumin_4h_R1 2 SPPVLGSAAASPVHLK 16 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 0 SPPVLGS(0.005)AAAS(0.995)PVHLK;SPPVLGS(0.031)AAAS(0.969)PVHLK ; 117.4 0.0015321 0 1939.14 1718.24 1583.5 1575.22 1965.59 2398.38 1663.95 1570.54 1957.61 1698.61 TRUE FALSE FALSE 1785.655023 1866.757009 1642.185903 1568.702157 1942.151623 1900.928953 1710.635959 2049.390416 1742.865081 1757.636571 1.015940981 1.062083618 0.934314824 0.892506553 1.10497907 1.081525603 0.973259198 1.165992134 0.991595822 1 10.77942108 -2.454831773 1.861129402 1.007946792 119.7491039 0.357841973 0.062611258 998.617895 5.587495538 0.008729687 505186.0372 0.003508878 2.454831773 118.7411571 SPQEEDFRCPS(ph)DEDFR ddPTM_HeLa_Curcumin_4h_R1 2 SPQEEDFRCPSDEDFR 16 1 Q8IXT5;B9ZVT1 Q8IXT5 RBM12B RNA-binding protein 12B 1 0 SPQEEDFRCPS(1)DEDFR;SPQEEDFRCPS(1)DEDFR ; 69.422 0.011335 25768000 3492.2 3749.6 3997.2 3867.4 5099.8 4937.1 3814.8 2792.7 3898.7 3029.2 TRUE FALSE FALSE 3215.788685 4073.698716 4145.339748 3851.397724 5038.988216 3913.089807 3921.833021 3644.181374 3471.022364 3134.464475 1.025945169 1.299647436 1.322503344 1.228725913 1.607607378 1.248407771 1.251197151 1.162616901 1.10737333 1 11.61400326 -7.26523736 5.057277979 1.011340002 1.309511197 0.506331708 0.115598806 0.088904772 7.162858156 0.018705167 0.022067408 5.43E-08 7.26523736 0.298171194 VHSIIESDPVT(ph)PPSDPSIPIPTLPSVTAAK ddPTM_HeLa_Curcumin_4h_R1 1 VHSIIESDPVTPPSDPSIPIPTLPSVTAAK 30 0 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 0 VHS(0.001)IIES(0.018)DPVT(0.414)PPS(0.414)DPS(0.153)IPIPTLPSVTAAK 79.373 6.33E-06 10711000 1048.9 731.14 868.75 696.37 1060.2 1726.6 1363.9 1718.6 1092 969.94 TRUE FALSE FALSE 965.8784582 794.3364837 900.9466392 693.4886055 1047.557807 1368.483697 1402.167363 2242.593229 972.210332 1003.645343 0.962370289 0.791451372 0.897674309 0.690969784 1.04375297 1.363513224 1.397074548 2.2344479 0.968679164 1 9.97103384 -3.865884525 0.922679709 0.942242972 3.896954892 0.909850873 0.126860338 0.846575867 0.33123612 0.020850206 2.979306158 0.000136181 3.865884525 2.954711919 up SPQGQLDT(ph)SESKPDSFFLEPLMPAVLKPAK ddPTM_HeLa_Curcumin_4h_R1 1 SPQGQLDTSESKPDSFFLEPLMPAVLKPAK 30 2 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 0 S(0.153)PQGQLDT(0.262)S(0.262)ES(0.262)KPDS(0.062)FFLEPLMPAVLKPAK 43.895 0.013293 12018000 1159.5 1099 811.73 1063.5 789.96 718.68 295.4 401.91 1030.7 983.01 TRUE FALSE FALSE 1067.724352 1193.992663 841.8134279 1059.099519 780.5402429 569.6176668 303.688129 524.4505088 917.6347887 1017.169524 1.049701476 1.173838416 0.827603863 1.041222228 0.767364952 0.560002687 0.298561962 0.515597938 0.902145382 1 9.990344428 -5.38135202 1.630628997 1.024794737 0.40031311 0.842601371 0.105013244 0.085717751 0.435644162 0.013531667 0.04288364 4.16E-06 5.38135202 -0.624481627 SPQGQLDTSES(ph)KPDSFFLEPLMPAVLKPAK ddPTM_HeLa_Curcumin_4h_R1 1 SPQGQLDTSESKPDSFFLEPLMPAVLKPAK 30 2 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 0 S(0.02)PQGQLDT(0.179)S(0.179)ES(0.603)KPDS(0.018)FFLEPLMPAVLKPAK 61.141 0.00056071 27017000 2772 2320.9 2458.4 2342.4 2322 1617.1 1149.7 934.3 2577.2 2249.9 TRUE FALSE FALSE 2552.593275 2521.508254 2549.510467 2332.707769 2294.311667 1281.695232 1181.957488 1219.163769 2294.487608 2328.083858 1.096435279 1.083083088 1.095111097 1.001986145 0.985493568 0.55053654 0.50769541 0.523676914 0.985569141 1 11.18492731 -5.281530796 3.337465475 1.049862623 0.513082012 0.973955866 0.038188221 0.029240081 0.678438125 0.00642536 0.016561349 5.23E-06 5.281530796 -0.53678061 SPQNDDHS(ph)DTDSEENRDNQQFLTTVK ddPTM_HeLa_Curcumin_4h_R1 2 SPQNDDHSDTDSEENRDNQQFLTTVK 26 1 Q86W56-3;Q86W56-2;Q86W56 Q86W56-3 PARG Poly(ADP-ribose) glycohydrolase 1 0 S(0.004)PQNDDHS(0.479)DT(0.479)DS(0.037)EENRDNQQFLT(0.001)TVK;S(0.003)PQNDDHS(0.444)DT(0.444)DS(0.099)EENRDNQQFLT(0.008)T(0.002)VK ; 56.164 0.0027606 14602300 1134.02 721.43 884.67 950.79 1334.13 1299.06 855.21 909.7 1034.33 993.27 TRUE FALSE FALSE 1044.26112 783.7871946 917.4566484 946.8558829 1318.221371 1029.620313 879.2048909 1187.063342 920.8665868 1027.786059 1.016029661 0.762597613 0.892653331 0.921257761 1.282583433 1.001784665 0.855435704 1.154971244 0.895971082 1 10.00532427 SPQPVCS(ph)PAGS(ph)EGTPK ddPTM_HeLa_Curcumin_4h_R1 1 SPQPVCSPAGSEGTPK 16 0 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 2 0 S(0.121)PQPVCS(0.879)PAGS(1)EGTPK 125.59 0.0014149 8773800 3178.6 2814.1 3298.4 4024.9 3185.8 4138.3 2931 1381.6 3645.1 4384.1 TRUE FALSE FALSE 2927.010456 3057.338265 3420.641606 4008.24603 3147.811416 3279.969932 3013.235972 1802.84348 3245.24165 4536.447149 0.645220888 0.673949936 0.75403537 0.883565023 0.69389355 0.723026153 0.664228166 0.39741309 0.715370761 1 12.14734714 -13.52287875 0.243434917 2.946248991 0.646029865 0.057515679 0.144539642 28.28631957 0.371098408 26.3957359 0.074635915 3.00E-14 13.52287875 -2.300219126 SPQPVCSPAGS(ph)EGTPK ddPTM_HeLa_Curcumin_4h_R1 1 SPQPVCSPAGSEGTPK 16 0 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 1 0 S(0.275)PQPVCS(0.067)PAGS(0.651)EGT(0.007)PK 97.502 0.0035573 44269000 3769.2 3005.6 2965.9 3550.3 3038.4 3682.9 3552.3 1620.1 4070.3 2867 TRUE FALSE FALSE 3470.863843 3265.390671 3075.818863 3535.609799 3002.169064 2919.025025 3651.967977 2114.061032 3623.798273 2966.628037 1.169969339 1.100707817 1.036806376 1.191794103 1.011980278 0.983953832 1.231016471 0.712614121 1.221520942 1 11.53460833 -4.246603819 24.45710411 1.084224451 0.712613764 0.615475457 0.091765467 1013.308459 1670448.853 0.011957895 0.353372089 5.67E-05 4.246603819 -0.371610687 SPQQTVPYVVPLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SPQQTVPYVVPLSPK 15 0 Q9UQR0;H0Y6S1;B4DRC2 Q9UQR0 SCML2 Sex comb on midleg-like protein 2 1 0 S(0.148)PQQT(0.026)VPY(0.293)VVPLS(0.534)PK;SPQQTVPYVVPLS(1)PK ; 141.6 0.0005247 80706000 9092.8 7863.3 9107.9 8519.8 8216.7 10283.7 7631 5411.3 9821.7 8133.6 TRUE FALSE FALSE 8373.095285 8542.968614 9445.446786 8484.547325 8118.721219 8150.744699 7845.105322 7061.180459 8744.284083 8416.241995 0.9948734 1.015057388 1.122287928 1.008115894 0.964649213 0.968454175 0.932138754 0.838994466 1.038977264 1 13.03896047 -4.14577537 0.961684853 1.008125887 0.722430943 0.674408929 0.039618745 1.197587375 0.727208651 0.006342863 0.373068044 7.15E-05 4.14577537 -0.285694944 SPQTLAPVGEDAMKT(ph)PS(ph)PAAEDAREPEAK ddPTM_HeLa_Curcumin_4h_R1 1 SPQTLAPVGEDAMKTPSPAAEDAREPEAK 29 2 Q92797 Q92797 SYMPK Symplekin 2 0 S(0.001)PQT(0.004)LAPVGEDAMKT(0.996)PS(0.998)PAAEDAREPEAK 64.315 0.00038063 21146000 2906.4 2872.7 3051.9 2854.1 2383.2 1852.6 1460.3 1533.3 3172.5 3469.7 TRUE FALSE FALSE 2676.355373 3121.003387 3165.006099 2842.29049 2354.781897 1468.349877 1501.272088 2000.796112 2824.484687 3590.271817 0.745446448 0.869294456 0.881550551 0.79166443 0.655878445 0.408980142 0.41814998 0.557282628 0.786704971 1 11.80987736 -5.61908802 2.012486181 0.874935744 0.455975944 0.834084632 0.076717361 0.114800724 0.935576833 0.015462043 0.037195433 2.40E-06 5.61908802 -0.418959799 SPQVLGSSLSVRS(ph)PTGS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 SPQVLGSSLSVRSPTGSPSR 20 1 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 2 0 SPQVLGS(0.064)S(0.071)LS(0.442)VRS(0.515)PT(0.263)GS(0.45)PS(0.195)R 75.703 0.016392 8111700 1583.4 1314.6 1608.6 1647.1 1232.1 2235.2 1426.8 740.47 1690.8 1621.9 TRUE FALSE FALSE 1458.072219 1428.228166 1668.216131 1640.284737 1217.408012 1771.594324 1466.832168 966.2358943 1505.32347 1678.260904 0.868799491 0.851016765 0.994014773 0.977371714 0.725398541 1.055613176 0.874019149 0.575736402 0.896954381 1 10.7127513 -4.283011573 3.945669499 0.929457668 0.549893786 0.566951264 0.089615575 0.11767027 3.684718404 0.012315077 0.122892344 5.21E-05 4.283011573 -0.379563882 SPRIKQLS(ph)FSRTHS(ph)ASFYS(ph)VS(ph)QPK ddPTM_HeLa_Curcumin_4h_R1 1 SPRIKQLSFSRTHSASFYSVSQPK 24 3 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 4 0 S(0.107)PRIKQLS(0.33)FS(0.33)RT(0.337)HS(0.676)AS(0.282)FY(0.253)S(0.753)VS(0.931)QPK 42.309 0.0086361 0 253.87 349.82 257.77 316.61 430.72 312.25 308.78 328.6 356.77 241.23 TRUE FALSE FALSE 233.7759216 380.056882 267.323183 315.2999517 425.5839453 247.4858302 317.4435358 428.7886273 317.6332236 249.6127245 0.936554505 1.522586169 1.070951745 1.263156565 1.704976964 0.991479223 1.271744204 1.71781558 1.272504133 1 7.96354767 -7.276082982 24.42248184 0.970039611 1.343478464 0.196719987 0.246204065 433.7583144 723417.0303 0.036657498 0.042023016 5.30E-08 7.276082982 0.373438852 SPRPAS(ph)PASNVVVLPSGSTVYVK ddPTM_HeLa_Curcumin_4h_R1 2 SPRPASPASNVVVLPSGSTVYVK 23 1 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 0 S(0.104)PRPAS(0.886)PAS(0.01)NVVVLPSGSTVYVK;S(0.252)PRPAS(0.72)PAS(0.028)NVVVLPSGSTVYVK ; 94.275 5.89E-05 60961000 4893.8 3580.3 3918.6 3823.7 3366.7 6091.4 5427.4 3005.7 4533.5 4080.5 TRUE FALSE FALSE 4506.450566 3889.765178 4063.826763 3807.878543 3326.554301 4827.974976 5579.678237 3922.124093 4036.186392 4222.297071 1.067298319 0.921243843 0.962468224 0.901849983 0.787854157 1.143447487 1.321479314 0.92890766 0.955921936 1 12.04381237 -5.049731405 24.99695926 0.99349039 1.152011582 0.28039028 0.119273722 357.5265987 179706.6053 0.016843062 0.042942345 8.92E-06 5.049731405 0.158521192 SPS(ph)DSGYSYETIGK ddPTM_HeLa_Curcumin_4h_R1 1 SPSDSGYSYETIGK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(0.081)PS(0.877)DS(0.042)GYSYETIGK 130.66 0.0010705 46966000 1905.3 1796 2167.6 2202.4 1947.9 2305.7 1674.6 2314.8 2151.2 1759.4 TRUE FALSE FALSE 1754.493495 1951.238237 2247.933163 2193.287052 1924.672565 1827.471829 1721.584769 3020.571864 1915.218742 1820.539019 0.963721995 1.071791495 1.234762419 1.204745973 1.057199293 1.003808109 0.945645631 1.659163485 1.052006423 1 10.83014995 -4.257079054 24.89761941 1.024552696 1.659163753 0.77346656 0.095743748 159.3118506 909640.5584 0.015250735 0.160940759 5.53E-05 4.257079054 0.634611056 SPS(ph)FASEWDEIEK ddPTM_HeLa_Curcumin_4h_R1 1 SPSFASEWDEIEK 13 0 A0A3B3ISP1;Q92625 A0A3B3ISP1 ANKS1A Ankyrin repeat and SAM domain-containing protein 1A 1 0 S(0.185)PS(0.63)FAS(0.185)EWDEIEK 152 0.00046915 101820000 4298 3765.6 4007.6 3647 3918.5 5681 4414.5 2341.5 4799.9 3841.9 TRUE FALSE FALSE 3957.808765 4091.081685 4156.125181 3631.90968 3871.774447 4502.696562 4538.358989 3055.412571 4273.362979 3975.405739 0.99557354 1.029097897 1.045459371 0.913594717 0.973931895 1.132638241 1.141609005 0.7685788 1.074950146 1 11.9568864 ASVS(ph)GPNS(ph)PSETRR ddPTM_HeLa_Curcumin_4h_R1 1 ASVSGPNSPSETRR 14 1 C9J453;A0A087X255;O15344-2;O15344;A0A087X0X0 C9J453 MID1 E3 ubiquitin-protein ligase Midline-1 2 0 AS(0.197)VS(0.795)GPNS(0.505)PS(0.369)ET(0.133)RR 111.66 0.0041727 44534000 4926 3581.7 4054.7 4609.5 3944.2 4824.4 3294.6 1082.8 4309.4 3932.2 TRUE FALSE FALSE 4536.101902 3891.286188 4204.970749 4590.42711 3897.167991 3823.765058 3387.037609 1412.940735 3836.669602 4068.843657 1.114838093 0.956361688 1.033455965 1.128189603 0.957807259 0.939767015 0.832432478 0.347258547 0.942938566 1 11.99040313 -4.184921282 1.344377532 1.045449149 3.88E-21 0.901921266 0.065667177 0.306980615 0.420506278 0.00928717 0.456880036 6.53E-05 4.184921282 -1.045449149 down SPS(ph)PAHLPDDPKVAEK ddPTM_HeLa_Curcumin_4h_R1 1 SPSPAHLPDDPKVAEK 16 1 A0A087X183;H0Y4V9;Q92615;H0Y641 A0A087X183 LARP4B La-related protein 4B 1 0 S(0.132)PS(0.868)PAHLPDDPKVAEK 102.57 0.00097937 10222000 4611.8 3328 3210.5 3397.2 3281.9 5290.2 2614.3 1144.4 5996.6 4277.5 TRUE FALSE FALSE 4246.771164 3615.657491 3329.483954 3383.143287 3242.765486 4192.952887 2687.650222 1493.322292 5338.787983 4426.142807 0.959474502 0.816886768 0.75223148 0.764354752 0.732639146 0.94731532 0.607221759 0.33738683 1.206194245 1 12.11183428 -3.935828041 0.302001018 1.002404264 5.19E-17 0.666452637 0.130444677 4.186342279 0.239914328 0.050796925 1.600946746 0.000115924 3.935828041 -1.002404264 SPS(ph)PEPIYNSEGK ddPTM_HeLa_Curcumin_4h_R1 1 SPSPEPIYNSEGK 13 0 Q15637-5;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-6 Q15637-5;Q15637-6 SF1 Splicing factor 1 1 0 S(0.358)PS(0.642)PEPIYNSEGK 139.48 0.0010182 15942000 3295 3023.4 3500.3 3343.3 3896.1 4098.3 3601.8 1864.3 2851.1 2854.3 TRUE FALSE FALSE 3034.197273 3284.729224 3630.024197 3329.46631 3849.641552 3248.266383 3702.856814 2432.716488 2538.341463 2953.486713 1.027327213 1.112153039 1.229064001 1.12730025 1.303422675 1.099807346 1.253723878 0.823676124 0.859438931 1 11.52820341 -7.211754278 3.210901922 1.011879044 1.150954444 0.241710633 0.131883741 0.273717111 5.615246539 0.01936554 0.023416099 6.14E-08 7.211754278 0.1390754 SPS(ph)PISNQPSPR ddPTM_HeLa_Curcumin_4h_R1 2 SPSPISNQPSPR 12 0 F6SS63;Q8N5C8-2;Q8N5C8 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 0 SPS(1)PISNQPSPR;S(0.068)PS(0.922)PIS(0.009)NQPSPR ; 157.33 0.00029154 70742000 2779.2 2532.6 2692 3106.9 3164.4 3105.4 1981.84 1990.59 2863.7 2827.7 TRUE FALSE FALSE 2559.223387 2751.506659 2791.767888 3094.044471 3126.666597 2461.305035 2037.445097 2597.511727 2549.559275 2925.962365 0.874660392 0.940376641 0.954136636 1.057445068 1.068594263 0.841195042 0.696333323 0.887746117 0.871357508 1 11.5146955 -5.013493325 23.92465179 0.956801721 0.786220814 0.482985902 0.075633784 229.5616793 407033.9858 0.011130883 0.029891723 9.69E-06 5.013493325 -0.170580907 FAS(ph)ENDLPEWK ddPTM_HeLa_Curcumin_4h_R1 2 FASENDLPEWK 11 0 P43487-2;P43487;F6WQW2;C9JXG8;C9JJ34;C9JGV6;C9JDM3;C9JIC6 P43487-2 RANBP1 Ran-specific GTPase-activating protein 1 0 FAS(1)ENDLPEWK;FAS(1)ENDLPEWK ; 170 0.00024108 121931000 6502.3 4983.2 4245.3 4181.3 5200.2 14804.7 14883.7 46728 8350.5 4504.9 TRUE FALSE FALSE 5987.636094 5413.925603 4402.634553 4163.998888 5138.191011 11734.03834 15301.29656 60975.15209 7434.471042 4661.44494 1.28450216 1.161426483 0.944478506 0.89328501 1.102274311 2.517253446 3.282522214 13.0807406 1.594885521 1 12.18656151 -3.854194796 1.422395844 1.122088217 32.5818675 0.98516231 0.431543839 0.240592068 0.198906755 0.057053472 14.30411842 0.000139896 3.854194796 31.45977928 up SPS(ph)PPLPTHIPPEPPR ddPTM_HeLa_Curcumin_4h_R1 1 SPSPPLPTHIPPEPPR 16 0 Q8IZ21-3;Q8IZ21;Q8IZ21-2 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 0 S(0.463)PS(0.537)PPLPTHIPPEPPR 65.47 0.014938 8206500 1962.8 1779.7 2027.4 1842.4 2260.8 2922.7 2505.1 2167.8 2318.6 2084.3 TRUE FALSE FALSE 1807.442309 1933.529338 2102.537227 1834.776637 2233.841437 2316.499074 2575.386364 2828.752241 2064.255381 2156.72927 0.838047841 0.896509991 0.974873044 0.850721814 1.035754217 1.074079676 1.194116665 1.311593569 0.957123089 1 11.07462937 -4.779504028 1.034956621 0.919034799 1.358568808 0.855632334 0.053930719 0.303355829 0.421129844 0.010711198 0.119855229 1.66E-05 4.779504028 0.439534009 SPS(ph)PSLSSLLLPSSPGPR ddPTM_HeLa_Curcumin_4h_R1 1 SPSPSLSSLLLPSSPGPR 18 0 Q8TER5;Q8TER5-4;Q8TER5-3;Q8TER5-2 Q8TER5 ARHGEF40 Rho guanine nucleotide exchange factor 40 1 0 S(0.197)PS(0.792)PS(0.01)LS(0.001)SLLLPSSPGPR 79.545 0.0065722 9079300 276.75 154.62 261.37 300.56 272.29 179.36 164.17 213.86 223.44 199.18 TRUE FALSE FALSE 254.8449455 167.9846638 271.0566021 299.3163624 269.0431196 142.1587142 168.7761684 279.0649295 198.929191 206.1014902 1.236502197 0.815057978 1.315160807 1.452276556 1.305391433 0.689751025 0.818898341 1.354017039 0.965200159 1 7.687211126 -3.932775659 18.14396695 1.09995471 5.568145966 0.098627204 0.24246019 12302826.97 52902382.59 0.034042793 2131490391 0.000116741 3.932775659 4.468191255 SPS(ph)TTYLHTPTPSEDAAIPSK ddPTM_HeLa_Curcumin_4h_R1 1 SPSTTYLHTPTPSEDAAIPSK 21 0 Q13111 Q13111 CHAF1A Chromatin assembly factor 1 subunit A 1 0 S(0.209)PS(0.253)T(0.253)T(0.253)Y(0.033)LHT(0.001)PTPSEDAAIPSK 77.894 0.00066653 37550000 2608 2042.1 2151.3 2147.2 2824.2 2979.7 2379.6 2196.6 2819.1 2370.3 TRUE FALSE FALSE 2401.574048 2218.610025 2231.02907 2138.315455 2790.52326 2361.676632 2446.365172 2866.333228 2509.851783 2452.667749 0.979168112 0.904570146 0.909633631 0.8718325 1.137750216 0.962901165 0.997430318 1.168659404 1.023315035 1 11.2601361 -4.262378712 3.899822911 0.978702189 1.18664742 0.403402334 0.070487886 0.189529282 5.756502642 0.009408048 0.111696567 5.47E-05 4.262378712 0.207945231 SPSAPAATSSASSSTSSYK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 SPSAPAATSSASSSTSSYKR 20 1 A0A087X0S7;A0A0C4DH00;A0A087WTU1;A0A0B4J2G4;Q15345-3;Q15345 A0A087X0S7 LRRC41 Leucine-rich repeat-containing protein 41 0 1 SPSAPAATSSASSSTSSYK(1)R 204.67 1.86E-19 1319600 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 TADGRVS(ph)PAGGTLDDKPK ddPTM_HeLa_Curcumin_4h_R1 1 TADGRVSPAGGTLDDKPK 18 2 C9JA69;Q8WY36-2;Q8WY36 C9JA69 BBX HMG box transcription factor BBX 1 0 T(0.467)ADGRVS(0.507)PAGGT(0.027)LDDKPK 66.401 0.012627 22215000 2767.9 2825.5 2463.2 2886.7 2892.9 2842.5 2005.7 670.99 2617.2 2329 TRUE FALSE FALSE 2548.817794 3069.72363 2554.488359 2874.7556 2858.404057 2252.933458 2061.974544 875.5717621 2330.099708 2409.932577 1.057630333 1.273779881 1.05998333 1.19287802 1.186092957 0.934853315 0.855615034 0.363317949 0.966873402 1 11.23477707 -4.18419539 1.507602254 1.069230143 6.76E-16 0.834968525 0.098178555 0.424275842 0.760722456 0.015018652 0.70938701 6.54E-05 4.18419539 -1.069230143 down SQEEPKDTFEHDPSES(ph)IDEFNK ddPTM_HeLa_Curcumin_4h_R1 1 SQEEPKDTFEHDPSESIDEFNK 22 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 SQEEPKDTFEHDPS(0.007)ES(0.993)IDEFNK 101.73 2.95E-05 40099000 4399.3 3804.2 3859.1 4395.5 4449.4 5688.7 5046.6 6578 4679.6 4093.8 TRUE FALSE FALSE 4051.090763 4133.018097 4002.121641 4377.312586 4396.343811 4508.799495 5188.194014 8583.601919 4166.259588 4236.059245 0.956334774 0.975675234 0.944774709 1.033345459 1.037838131 1.064385372 1.224768992 2.026317722 0.983522502 1 12.04850705 -3.831436897 1.316246666 0.982608942 3.789069482 0.989007403 0.032499872 0.267204026 0.185047109 0.00524383 1.324624016 0.000147422 3.831436897 2.80646054 up YPDVASPT(ph)LR ddPTM_HeLa_Curcumin_4h_R1 1 YPDVASPTLR 10 0 A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-11;Q8IVL1;A0A0A0MTL4;Q8IVL1-4;Q8IVL1-3;Q8IVL1-2;Q8IVL1-5;E9PNV5 A0A0A0MTE8 NAV2 Neuron navigator 2 1 0 YPDVAS(0.45)PT(0.55)LR 140.63 0.0043163 70372000 4163.1 3586.5 3109.7 3757.9 3800.4 3969.5 2794.7 865.59 3724.7 2954.8 TRUE FALSE FALSE 3833.586242 3896.501079 3224.948218 3742.350806 3755.082712 3146.180955 2873.11176 1129.504406 3316.109729 3057.47908 1.253838912 1.274416268 1.0547736 1.223998826 1.228163011 1.029011441 0.939699565 0.369423429 1.084589507 1 11.57812691 -4.183836747 1.648167776 1.14165416 9.07E-12 0.869044256 0.09106566 0.39310465 0.872592087 0.016607617 0.753741813 6.55E-05 4.183836747 -1.14165416 down EADES(ph)LNFEEQILEAAK ddPTM_HeLa_Curcumin_4h_R1 2 EADESLNFEEQILEAAK 17 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 0 EADES(1)LNFEEQILEAAK;EADES(1)LNFEEQILEAAK ; 211.29 2.29E-11 5078500 2363.5 1932 1961.64 2340.9 2672.2 4474.2 4712.2 11283.2 3001.7 2356.27 TRUE FALSE FALSE 2176.426481 2098.993471 2034.340104 2331.213976 2640.33576 3546.200485 4844.41165 14723.39574 2672.42102 2438.150207 0.892654798 0.860895881 0.834378496 0.956140425 1.082925799 1.454463501 1.986920919 6.038756634 1.096085472 1 11.25157129 -3.831289073 1.359475263 0.94311766 14.78367031 0.990041768 0.150674274 0.223224445 0.163072258 0.021297733 5.653371718 0.000147472 3.831289073 13.84055265 up SPSFGDPQLS(ph)PEARPR ddPTM_HeLa_Curcumin_4h_R1 2 SPSFGDPQLSPEARPR 16 1 O95425-3;O95425-2 O95425-3 SVIL Supervillin 1 0 SPSFGDPQLS(1)PEARPR;SPSFGDPQLS(1)PEARPR ; 132.62 0.00019594 128577000 8282.7 6021.4 7157.8 7492.4 7672.5 10554.2 9770.4 10287.4 8663.1 7053.9 TRUE FALSE FALSE 7627.115555 6541.862985 7423.074365 7461.398434 7581.010449 8365.13995 10044.53113 13423.9809 7712.779604 7299.0225 1.044950273 0.896265628 1.016995682 1.022246258 1.038633659 1.146063045 1.37614744 1.839147763 1.056686646 1 12.83348755 -4.140732675 1.122264744 1.010064178 2.415311526 0.974989805 0.041200789 0.209420469 0.177747317 0.006132696 0.368467278 7.23E-05 4.140732675 1.405247347 SPSGGAAGPLLTPS(ph)QSLDGSRR ddPTM_HeLa_Curcumin_4h_R1 1 SPSGGAAGPLLTPSQSLDGSRR 22 1 Q96CX2 Q96CX2 KCTD12 BTB/POZ domain-containing protein KCTD12 1 0 SPSGGAAGPLLT(0.054)PS(0.546)QS(0.151)LDGS(0.249)RR 90.765 0.00049281 8575300 1527 1691.4 1477.8 1254.3 1132.2 1592.3 1114.5 1042.1 1780.7 1715.3 TRUE FALSE FALSE 1406.136339 1837.597079 1532.568568 1249.110039 1118.699254 1262.039031 1145.76987 1359.831493 1585.361665 1774.906547 0.792231197 1.035320469 0.863464372 0.703761018 0.630286285 0.711045341 0.64553814 0.766142586 0.893208528 1 10.79352735 -6.299082252 3.881502681 0.910473036 0.684797143 0.71919962 0.070889851 0.120976709 3.960339983 0.013886764 0.022180989 5.02E-07 6.299082252 -0.225675894 SPSGGAAGPLLTPSQSLDGS(ph)RR ddPTM_HeLa_Curcumin_4h_R1 1 SPSGGAAGPLLTPSQSLDGSRR 22 1 Q96CX2 Q96CX2 KCTD12 BTB/POZ domain-containing protein KCTD12 1 0 S(0.046)PS(0.014)GGAAGPLLT(0.072)PS(0.187)QS(0.22)LDGS(0.462)RR 67.227 0.0046487 6355700 1009.9 987.51 1078.5 954.86 877.77 982.98 753.34 949.76 1168 904.02 TRUE FALSE FALSE 929.9653494 1072.865964 1118.470159 950.9090423 867.303166 779.0988675 774.4766929 1239.337452 1039.873322 935.4346277 0.994153222 1.146917093 1.195668971 1.016542486 0.927165983 0.832873666 0.82793246 1.324878741 1.11164724 1 9.869493025 -5.861010539 7.065751891 1.027698297 0.95737171 0.031434217 0.14820038 0.600328637 37.17880738 0.021336837 0.038906801 1.38E-06 5.861010539 -0.070326588 SPSGPVKS(ph)PPLSPVGTTPVK ddPTM_HeLa_Curcumin_4h_R1 2 SPSGPVKSPPLSPVGTTPVK 20 1 C9J4K0;Q9BVC5-2;Q9BVC5 C9J4K0 C2orf49 Ashwin 1 0 S(0.005)PS(0.019)GPVKS(0.975)PPLS(0.001)PVGTTPVK;S(0.005)PS(0.019)GPVKS(0.976)PPLSPVGTTPVK ; 79.177 0.0012476 63930000 3299.9 2946.8 3076.5 2936.5 3301.9 4422.8 4113.9 4770.9 3427.8 3562.6 TRUE FALSE FALSE 3038.709433 3201.508261 3190.517796 2924.349541 3262.526999 3505.461425 4229.324962 6225.525447 3051.778916 3686.400085 0.82430267 0.868464678 0.865483323 0.793280565 0.885017069 0.950917248 1.147277795 1.688781821 0.827847994 1 11.84799694 -4.217341697 1.671719088 0.896358657 2.031610401 0.947737561 0.05820207 0.227404845 0.556823851 0.011163813 0.427676413 6.06E-05 4.217341697 1.135251744 SPSGS(ph)AFGSQENLR ddPTM_HeLa_Curcumin_4h_R1 1 SPSGSAFGSQENLR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 S(0.177)PS(0.066)GS(0.403)AFGS(0.354)QENLR 129.29 0.0011152 54341000 648.26 558.68 503.42 444.56 352.45 672.88 454.6 324.44 550.41 737.86 TRUE FALSE FALSE 596.949537 606.9698098 522.0771881 442.7205285 348.2472639 533.3171031 467.3548525 423.3602625 490.0314001 763.5005801 0.781858655 0.794982775 0.683794095 0.579856178 0.456119187 0.698515649 0.612121149 0.55449894 0.641821909 1 9.576485443 -7.639640637 0.40128859 1.007917915 0.553182829 0.231015142 0.126567891 0.304066274 0.1345347 0.050652185 0.041376636 2.29E-08 7.639640637 -0.454735086 SPSGSAFGS(ph)QENLR ddPTM_HeLa_Curcumin_4h_R1 1 SPSGSAFGSQENLR 14 0 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A1B0GWE0 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 SPSGSAFGS(1)QENLR 161.94 0.00026149 58495000 1099.5 787.16 986.85 697.88 1408.8 964.99 747.34 480.42 1229.5 837.14 TRUE FALSE FALSE 1012.473415 855.1986029 1023.423529 694.9923575 1392.00098 764.8401963 768.308349 626.8978464 1094.626926 866.2305527 1.168826719 0.987264418 1.181467827 0.802317992 1.606963615 0.882952228 0.886955957 0.723707845 1.263666956 1 9.758607248 -5.022948336 24.797165 1.096923859 0.825237225 0.313976725 0.205570177 610.5747165 659766.9869 0.025835322 0.066417892 9.49E-06 5.022948336 -0.271686634 AYSVLQATVAAATT(ph)TPTAK ddPTM_HeLa_Curcumin_4h_R1 2 AYSVLQATVAAATTTPTAK 19 0 A0A087WZT0;M0QZ22;Q5PRF9 A0A087WZT0 SAMD4B Protein Smaug homolog 2 1 0 AYSVLQATVAAAT(0.023)T(0.477)T(0.477)PT(0.023)AK;AYSVLQATVAAAT(0.068)T(0.462)T(0.462)PT(0.008)AK ; 145.61 2.40E-06 0 1452.12 1148.83 1521.21 1320.4 1188.7 2308.1 1872.44 3834 1563.3 1259.96 TRUE FALSE FALSE 1337.18317 1248.129746 1577.587381 1314.936535 1174.525529 1829.374042 1924.975627 5002.96895 1391.809901 1303.743516 1.025648951 0.957343013 1.210044277 1.008585292 0.900886957 1.403170194 1.476498715 3.837387406 1.067548857 1 10.34844436 -3.829072676 1.434835888 1.022205762 8.843728938 0.973783762 0.135374827 0.344707177 0.273759302 0.017892328 5.242663524 0.000148227 3.829072676 7.821523175 up SPSLS(ph)PSPPSPLEK ddPTM_HeLa_Curcumin_4h_R1 1 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 SPS(0.001)LS(0.836)PS(0.162)PPSPLEK 110.25 0.0029335 11679000 1971 1726.6 1771.6 2116.1 2143.4 2783.7 1926.5 1916.5 2027.3 1983.2 TRUE FALSE FALSE 1814.99327 1875.83961 1837.257054 2107.344139 2117.841355 2206.329241 1980.552405 2500.832028 1804.910262 2052.116052 0.884449624 0.914100159 0.895298807 1.02691275 1.032028063 1.075148376 0.9651269 1.218660136 0.879536155 1 11.00289661 -6.02974598 2.950810878 0.937904321 1.06509904 0.528974855 0.069126339 0.198774434 3.487835288 0.010766196 0.019625569 9.34E-07 6.02974598 0.127194718 VADPDHDHTGFLTEY(ph)VATR ddPTM_HeLa_Curcumin_4h_R1 2 VADPDHDHTGFLTEYVATR 19 0 P28482-2;P28482 P28482-2 MAPK1 Mitogen-activated protein kinase 1 1 0 VADPDHDHTGFLT(0.013)EY(0.986)VAT(0.001)R;VADPDHDHTGFLTEY(1)VATR ; 218.28 9.33E-18 93890000 2930.35 2367.2 2845.51 2766.37 2756.74 5181.7 6027.3 11139.8 2750.33 2369.03 TRUE FALSE FALSE 2698.409705 2571.81022 2950.967104 2754.923494 2723.867676 4106.95701 6196.409816 14536.27374 2448.62568 2451.353616 1.100783538 1.049138812 1.203811267 1.123837653 1.111168808 1.675383341 2.527750291 5.929896708 0.998887171 1 11.2593629 -3.81699662 1.154405405 1.062556725 13.92519715 0.99519917 0.100920561 0.172792919 0.093410768 0.015305841 3.438051394 0.000152406 3.81699662 12.86264043 up RGSGDT(ph)SSLIDPDTSLSELRDIYDLK ddPTM_HeLa_Curcumin_4h_R1 1 RGSGDTSSLIDPDTSLSELRDIYDLK 26 2 C9JSU1;Q9Y608-4;Q9Y608 C9JSU1 LRRFIP2 Leucine-rich repeat flightless-interacting protein 2 1 0 RGS(0.021)GDT(0.323)S(0.323)S(0.323)LIDPDT(0.003)S(0.003)LS(0.003)ELRDIYDLK 71.002 0.0011289 76497000 1673.8 1316.1 1602.7 1454.3 1338.8 2196 1713.1 2281.1 1614.8 1380.2 TRUE FALSE FALSE 1541.316964 1429.85782 1662.097472 1448.282492 1322.835684 1740.524846 1761.164975 2976.596889 1437.66048 1428.161847 1.079231298 1.001187521 1.1638019 1.014088491 0.926250542 1.218716807 1.233169041 2.084215381 1.00665095 1 10.47994377 -3.802520585 1.345188628 1.039238539 4.027004511 0.942111771 0.076772013 0.589381989 0.398840664 0.010678276 3.250686772 0.000157572 3.802520585 2.987765972 up ASS(ph)VTTFTGEPNTCPR ddPTM_HeLa_Curcumin_4h_R1 2 ASSVTTFTGEPNTCPR 16 0 H0YFA4;P52943;P52943-2 H0YFA4 CRIP2 Cysteine-rich protein 2 1 0 AS(0.004)S(0.768)VT(0.225)T(0.003)FTGEPNTCPR;AS(0.002)S(0.993)VT(0.004)T(0.001)FTGEPNTCPR ; 199.38 5.38E-08 123444000 3413.5 1920.52 2738.9 2601.3 3466.1 6126.7 6804.2 12587.1 3516.1 3092.3 TRUE FALSE FALSE 3143.317873 2086.521191 2840.406043 2590.53651 3424.769021 4855.953358 6995.107539 16424.84885 3130.392627 3199.757195 0.982361374 0.65208735 0.887694244 0.809604089 1.070321532 1.517600575 2.186136983 5.133154751 0.978321928 1 11.64374672 -3.794476315 1.138944175 0.943956052 12.37313281 0.988190944 0.138362443 0.305214075 0.155187153 0.022133589 5.389003571 0.000160518 3.794476315 11.42917676 up GSHQIS(ph)LDNPDYQQDFFPK ddPTM_HeLa_Curcumin_4h_R1 1 GSHQISLDNPDYQQDFFPK 19 0 P00533;E9PFD7 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 0 GS(0.016)HQIS(0.982)LDNPDY(0.002)QQDFFPK 75.945 0.0025169 0 761.12 386.59 589.21 902.47 769.4 1418.7 1033.8 1092.8 833.58 488.57 TRUE FALSE FALSE 700.8765489 420.005117 611.0466409 898.7358183 760.2254075 1124.445628 1062.805646 1425.989689 742.1383595 505.5477711 1.386370565 0.830792145 1.208682296 1.777746574 1.503765719 2.224212413 2.102285296 2.820682378 1.46798859 1 8.981703614 -3.782969404 0.415810327 1.112886301 4.7446949 0.817701535 0.246396641 1.981026965 0.174124104 0.058215187 3.873284161 0.000164828 3.782969404 3.631808599 up SPSMAVPSPGWVAS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 SPSMAVPSPGWVASPK 16 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 0 SPSMAVPS(0.001)PGWVAS(0.999)PK;SPSMAVPSPGWVAS(1)PK;SPSMAVPSPGWVAS(1)PK ;; 137.73 0.00041158 42595000 8497.1 6381.9 7064.7 7598.3 6457.8 7449.2 7637.9 5724.7 7572.7 6452.2 TRUE FALSE FALSE 7824.545569 6933.522999 7326.523997 7566.860248 6380.794953 5904.15195 7852.198918 7470.134677 6741.993756 6676.41347 1.171968394 1.038510127 1.097374216 1.133372024 0.955721958 0.884329884 1.17611034 1.11888437 1.009822682 1 12.70485759 -5.78323892 24.99617395 1.084147584 1.033255626 0.042950871 0.089960206 592.5093779 679391.8594 0.014870548 0.026971866 1.65E-06 5.78323892 -0.050891958 GAGES(ph)GEEDPFPSRDPR ddPTM_HeLa_Curcumin_4h_R1 1 GAGESGEEDPFPSRDPR 17 1 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 0 GAGES(0.994)GEEDPFPS(0.006)RDPR 54.292 0.019771 6550900 2410.9 1771.6 2015.4 2474.5 2148.4 2207.2 1638.8 858.94 2475.9 2212 TRUE FALSE FALSE 2220.074721 1924.72921 2090.092497 2464.261175 2122.781733 1749.40184 1684.780317 1120.826852 2204.299964 2288.866835 0.969944903 0.840909213 0.913156006 1.076629333 0.927437848 0.764309139 0.736076163 0.489686352 0.963052953 1 11.16041782 -4.183720217 0.798783502 0.976586602 0.165412891 0.831744427 0.06588119 0.773838886 0.326110546 0.011020303 0.571851844 6.55E-05 4.183720217 -0.811173711 down VTSSMS(ph)SPSMQPK ddPTM_HeLa_Curcumin_4h_R1 3 VTSSMSSPSMQPK 13 0 A0A2R8Y7R9;Q13136-2;Q13136 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 0 VTS(0.008)S(0.067)MS(0.633)S(0.281)PS(0.011)MQPK;VTS(0.01)S(0.055)MS(0.456)S(0.456)PS(0.022)MQPK;VTS(0.004)S(0.021)MS(0.395)S(0.395)PS(0.184)MQPK ;; 116.03 0.0012454 123610000 13291.5 10660 11042.8 11244.4 11710.1 12117 8205.6 3184.07 12742.7 9122.5 TRUE FALSE FALSE 12239.46375 11581.4029 11452.05588 11197.87365 11570.46471 9603.797613 8435.827052 4154.878285 11344.85769 9439.506196 1.296621189 1.226907707 1.213204975 1.186277483 1.225748939 1.017404662 0.893672495 0.440158436 1.201848641 1 13.20449568 -4.182828215 1.293764348 1.163268705 0.028949169 0.890374572 0.080225692 0.561360223 0.700839524 0.017514613 0.879256675 6.56E-05 4.182828215 -1.134319536 down SPSPPDGS(ph)PAATPEIR ddPTM_HeLa_Curcumin_4h_R1 5 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-2;O00499;O00499-9;O00499-7;O00499-4;O00499-11;O00499-3;O00499-5;O00499-10;O00499-8 O00499-6 BIN1 Myc box-dependent-interacting protein 1 1 0 S(0.001)PS(0.312)PPDGS(0.686)PAATPEIR;S(0.001)PS(0.008)PPDGS(0.99)PAAT(0.002)PEIR;S(0.209)PS(0.263)PPDGS(0.514)PAAT(0.014)PEIR;SPS(0.004)PPDGS(0.996)PAATPEIR;SPS(0.01)PPDGS(0.961)PAAT(0.028)PEIR ;;;; 234.36 3.05E-22 753857600 6746.43 5653.04 5961.88 6426.68 6808.94 6817.82 5552.69 4672.13 6918.66 6146.58 TRUE FALSE FALSE 6212.442947 6141.663588 6182.832517 6400.088101 6727.747838 5403.727279 5708.483537 6096.640929 6159.700308 6360.173197 0.976772606 0.965644079 0.972117005 1.006275757 1.057793181 0.849619517 0.897535863 0.958565237 0.968479964 1 12.63485034 -5.255580688 24.99980382 0.990989112 0.901469774 0.58008163 0.035282832 255.6100757 1090717.799 0.004821634 0.011945539 5.55E-06 5.255580688 -0.089519338 SPSPPTQHT(ph)GQPPGQPSAPSQLSAPR ddPTM_HeLa_Curcumin_4h_R1 1 SPSPPTQHTGQPPGQPSAPSQLSAPR 26 0 Q68EM7-5;Q68EM7-7;Q68EM7-3;Q68EM7-6;Q68EM7;I3L460;Q68EM7-2 Q68EM7-5 ARHGAP17 Rho GTPase-activating protein 17 1 0 S(0.035)PS(0.035)PPT(0.116)QHT(0.802)GQPPGQPS(0.01)APS(0.002)QLS(0.001)APR 64.013 0.0018886 129190000 1099 778.29 1098.9 806.1 1089 1650.2 1264.7 961.74 1075.2 1472.2 TRUE FALSE FALSE 1012.01299 845.5619196 1139.626201 802.7645718 1076.014386 1307.929918 1300.184078 1254.970099 957.25325 1523.35884 0.664330008 0.555064176 0.748100953 0.526970107 0.70634335 0.858582944 0.853498233 0.82381778 0.628383297 1 10.57304011 -9.253737394 1.00905697 0.998304663 0.71414459 0 0.156266409 0.385058426 0.709467252 0.076926351 0.021573398 5.58E-10 9.253737394 -0.284160073 SPSS(ph)DLDTDAEGDDFELLDQSELSQLDPASSR ddPTM_HeLa_Curcumin_4h_R1 1 SPSSDLDTDAEGDDFELLDQSELSQLDPASSR 32 0 K7EQI9;Q86VR2-2;Q86VR2 K7EQI9 FAM134C Protein FAM134C 1 0 S(0.069)PS(0.22)S(0.712)DLDTDAEGDDFELLDQSELSQLDPASSR 130.43 2.90E-13 2270200 122.75 173.91 168.24 125.8 0 187.14 62.27 56.241 176.99 116.5 TRUE FALSE FALSE 113.034208 188.9420055 174.4751224 125.2794729 0 148.3250545 64.01712861 73.388622 157.5746398 120.5483663 0.937666859 1.567354343 1.447345391 1.039246543 0 1.230419449 0.531049325 0.608789851 1.307148696 1 6.913468289 -5.951331583 24.9999848 1.064697994 0.619467664 0.389691268 0.352579297 116.3000457 59740.38549 0.050990813 0.092428694 1.12E-06 5.951331583 -0.44523033 SPSSESS(ph)PQHPTPPARPR ddPTM_HeLa_Curcumin_4h_R1 1 SPSSESSPQHPTPPARPR 18 1 O14733;O14733-4;O14733-3;O14733-2 O14733 MAP2K7 Dual specificity mitogen-activated protein kinase kinase 7 1 0 S(0.006)PS(0.102)S(0.102)ES(0.163)S(0.575)PQHPT(0.052)PPARPR 85.177 0.00221 0 332 215.24 183.95 149.28 193.8 260.52 256.44 0 228.32 186.27 TRUE FALSE FALSE 305.7218497 233.8443865 190.7673488 148.6623189 191.4890616 206.4852153 263.6350162 0 203.2738672 192.7428686 1.58616426 1.213245336 0.989750491 0.771298674 0.993494924 1.071298859 1.367806851 0 1.054637552 1 7.590533672 -6.72472948 3.502945722 1.281853851 0.8914984 0.176321569 0.361279846 0.296229759 7.568389865 0.060007897 0.084447278 1.88E-07 6.72472948 -0.390355451 KES(ph)KEETPEVTK ddPTM_HeLa_Curcumin_4h_R1 1 KESKEETPEVTK 12 2 P46821;D6RA32;D6RA40 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 KES(0.901)KEET(0.098)PEVT(0.001)K 51.03 0.018764 33664000 2508 1702.2 2064.3 2354.4 2461.7 3906.8 3207 3626 3059.6 2213.3 TRUE FALSE FALSE 2309.489154 1849.330583 2140.804774 2344.658117 2432.345835 3096.485641 3296.979789 4731.550708 2723.969535 2290.21201 1.008417187 0.807493182 0.934762705 1.023773391 1.062061427 1.352051962 1.439595886 2.065988077 1.189396232 1 11.16126544 -3.753549344 0.774195911 0.980125207 3.702158814 0.913129056 0.10126397 0.760647484 0.189977809 0.01300291 2.151176974 0.000176381 3.753549344 2.722033607 up SPT(ph)GPSNSFLANMGGTVAHK ddPTM_HeLa_Curcumin_4h_R1 1 SPTGPSNSFLANMGGTVAHK 20 0 H0Y6J6;Q5W012;Q96I25 H0Y6J6 RBM17 Splicing factor 45 1 0 S(0.394)PT(0.535)GPS(0.066)NS(0.004)FLANMGGTVAHK 154.67 1.63E-05 166140000 1568.1 1750.6 1767.7 1586.1 2422.8 2088.8 1679 1672.7 1648.6 1289.2 TRUE FALSE FALSE 1443.98323 1901.914063 1833.212517 1579.537138 2393.909692 1655.559334 1726.108221 2182.69853 1467.752705 1333.999604 1.082446521 1.425723109 1.374222685 1.184061175 1.794535534 1.241049345 1.293934583 1.63620628 1.100264723 1 10.38154252 -7.310502164 3.788677046 1.035141716 1.41445087 0.475596892 0.173092978 0.131763201 3.860935795 0.02827895 0.032710632 4.89E-08 7.310502164 0.379309154 SPTAPSVFS(ph)PTGNR ddPTM_HeLa_Curcumin_4h_R1 2 SPTAPSVFSPTGNR 14 0 H0Y3X6;A0A0C4DFX9;Q9H3P2;C9JEM7;H7C2C7;C9JHL4 H0Y3X6 NELFA Negative elongation factor A 1 0 SPTAPSVFS(0.972)PT(0.028)GNR;SPTAPS(0.004)VFS(0.869)PT(0.127)GNR ; 191.01 6.31E-06 20610800 2095.73 2114 2103.62 2358.6 2390.05 1891.38 1535.56 2004.32 2371.56 1846.76 TRUE FALSE FALSE 1929.850759 2296.72474 2181.582008 2348.840738 2361.550215 1499.086468 1578.643681 2615.427941 2111.405801 1910.934773 1.009898813 1.201885472 1.141630808 1.229157987 1.235808908 0.784478094 0.82611071 1.368664163 1.104907311 1 10.90006282 -7.472793633 24.14867225 1.004367033 1.099720724 0.022544798 0.17440368 574.7954726 277140.7508 0.029697757 0.03389902 3.37E-08 7.472793633 0.095353691 SPTTVLFTS(ph)SPIK ddPTM_HeLa_Curcumin_4h_R1 1 SPTTVLFTSSPIK 13 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 0 SPTTVLFT(0.002)S(0.499)S(0.499)PIK 124.38 0.0021031 19615000 1775.4 1503.6 1837.1 1504.9 1827.2 2284.7 2269.1 387.29 1909 1702 TRUE FALSE FALSE 1634.875217 1633.564484 1905.184542 1498.673123 1805.411833 1810.827466 2332.764839 505.3729381 1699.587476 1761.144373 0.928302779 0.927558529 1.081787826 0.850965512 1.025135622 1.028210687 1.324573314 0.286957132 0.965047217 1 10.78229747 -4.243351512 24.99392971 0.988963375 0.286956539 0.756737164 0.12299866 1453.496457 2008420.942 0.016055593 0.707668404 5.71E-05 4.243351512 -0.702006836 SPTTVLFTSS(ph)PIK ddPTM_HeLa_Curcumin_4h_R1 1 SPTTVLFTSSPIK 13 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 0 SPTTVLFT(0.002)S(0.393)S(0.605)PIK 107.53 0.0045778 19089000 1546.9 1144.9 1228.4 1402.8 1387.8 1989.3 1973.9 350.64 1377.1 1377.1 TRUE FALSE FALSE 1424.461233 1243.860054 1273.925585 1396.995585 1371.251391 1576.696756 2029.282322 457.5485219 1226.035575 1424.954122 0.999654101 0.872912352 0.894011649 0.980379342 0.96231266 1.106489487 1.424103618 0.32109702 0.860403543 1 10.47669976 -4.236934742 24.78063821 1.008841772 0.321096083 0.64212679 0.154535386 3113.620331 3148638.117 0.019602626 1.755992836 5.80E-05 4.236934742 -0.687745689 SPVDES(ph)GDEVQYGDVPVENGMAPFFEMK ddPTM_HeLa_Curcumin_4h_R1 3 SPVDESGDEVQYGDVPVENGMAPFFEMK 28 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;Q8WX93-4;D6R9F5;F8WA26 Q8WX93-3 PALLD Palladin 1 0 S(0.029)PVDES(0.969)GDEVQY(0.002)GDVPVENGMAPFFEMK;S(0.031)PVDES(0.969)GDEVQYGDVPVENGMAPFFEMK;S(0.139)PVDES(0.861)GDEVQYGDVPVENGMAPFFEMK ;; 74.874 5.33E-05 83021000 8123.9 6977.8 7578.7 7615.9 7781.7 9877 7201.6 4676.48 9046.3 7432.1 TRUE FALSE FALSE 7480.884743 7580.92994 7859.573289 7584.387424 7688.90831 7828.398863 7403.657514 6102.317224 8053.943523 7690.364922 0.972760697 0.985769858 1.022002645 0.986219445 0.999810593 1.017948946 0.962718621 0.793501646 1.047277158 1 12.90883634 -4.271926978 3.506930775 0.991787183 0.771748375 0.879163544 0.022982952 0.050864069 1.091443436 0.002327124 0.029090991 5.35E-05 4.271926978 -0.220038808 SPVGKS(ph)PPSTGSTYGSSQK ddPTM_HeLa_Curcumin_4h_R1 2 SPVGKSPPSTGSTYGSSQK 19 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 S(0.418)PVGKS(0.568)PPS(0.008)T(0.004)GS(0.001)T(0.001)Y(0.001)GSSQK;SPVGKS(0.989)PPS(0.008)T(0.002)GS(0.001)TYGSSQK ; 107.69 0.00057989 86299000 2257 2064.34 2012.73 2057.14 2631.12 2410.07 2117.84 1783.98 2198.97 1807.48 TRUE FALSE FALSE 2078.356068 2242.772351 2087.323544 2048.6281 2599.745612 1910.194315 2177.260891 2327.90729 1957.748493 1870.289795 1.111248146 1.199157669 1.116042845 1.0953533 1.390022882 1.021336009 1.16413023 1.24467732 1.04676211 1 10.86904611 -8.325683064 0.423650538 0.983761326 1.187858194 0.291824809 0.093446515 0.987977443 0.391566319 0.085734743 0.0360713 4.72E-09 8.325683064 0.204096868 SPVGLSSDGIS(ph)SSS(ph)S(ph)S(ph)SRK ddPTM_HeLa_Curcumin_4h_R1 1 SPVGLSSDGISSSSSSSRK 19 1 O60583-2;O60583 O60583-2 CCNT2 Cyclin-T2 4 0 S(0.006)PVGLS(0.003)S(0.005)DGIS(0.721)S(0.395)S(0.41)S(0.694)S(0.694)S(0.814)S(0.257)RK 46.569 0.013648 5311300 2706.9 2006.4 2186.3 2320.7 2319.6 2879.2 2317.1 1846.4 2521.4 2219.8 TRUE FALSE FALSE 2492.646009 2179.824276 2267.326201 2311.097558 2291.940285 2282.021465 2382.11159 2409.35886 2244.808728 2296.937885 1.085203925 0.949013158 0.987108191 1.006164587 0.997824234 0.993505954 1.037081414 1.048943847 0.977304934 1 11.16549613 -7.270150035 24.99510745 1.040235185 1.003100328 0 0.037640494 929.8849758 2668286.28 0.00692053 0.007966421 5.37E-08 7.270150035 -0.037134857 SPVLSNTTTEPAS(ph)TMSPPPAKK ddPTM_HeLa_Curcumin_4h_R1 1 SPVLSNTTTEPASTMSPPPAKK 22 1 Q9P275;A0A075B784 Q9P275 USP36 Ubiquitin carboxyl-terminal hydrolase 36;Ubiquitin carboxyl-terminal hydrolase 1 0 SPVLSNT(0.001)T(0.001)T(0.001)EPAS(0.679)T(0.239)MS(0.078)PPPAKK 65.387 0.0037321 0 956.54 985.15 849.5 854.03 1133.3 986.81 875.95 566.47 876.35 835.1 TRUE FALSE FALSE 880.8288497 1070.301976 880.9832173 850.4962501 1119.786138 782.1344824 900.5267995 739.1840953 780.2165975 864.1196628 1.019336658 1.238603891 1.0195153 0.984234345 1.295869294 0.905122885 1.042132054 0.855418673 0.902903418 1 9.7550873 -3.618616379 1.450174985 1.039733485 0.199180639 0.177513949 0.121559109 8.728447118 4.293826826 0.015845317 16.85108753 0.000240649 3.618616379 -0.840552846 SPVPSPGS(ph)SSPQLQVK ddPTM_HeLa_Curcumin_4h_R1 2 SPVPSPGSSSPQLQVK 16 0 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 0 SPVPSPGS(0.91)S(0.045)S(0.045)PQLQVK;SPVPS(0.013)PGS(0.555)S(0.216)S(0.216)PQLQVK ; 139.77 0.00039749 67397200 4092.2 4139.9 3890.5 3681.9 4326 6533.9 5237.9 2522.4 4364.3 4005.4 TRUE FALSE FALSE 3768.298052 4497.734509 4034.685352 3666.665273 4274.415275 5178.695488 5384.861377 3291.468148 3885.547209 4144.587352 0.909209466 1.085206832 0.973483006 0.884687657 1.031324692 1.249508105 1.29925151 0.794160641 0.937499172 1 12.01701275 -5.515043455 22.94604084 0.963412087 1.134070462 0.193192579 0.134992708 123.6581372 362136.3945 0.018263746 0.037955406 3.05E-06 5.515043455 0.170658375 SPVPSPGSS(ph)SPQLQVK ddPTM_HeLa_Curcumin_4h_R1 1 SPVPSPGSSSPQLQVK 16 0 Q8N3F8 Q8N3F8 MICALL1 MICAL-like protein 1 1 0 SPVPS(0.128)PGS(0.066)S(0.478)S(0.328)PQLQVK 125.39 0.00060557 68669000 4613.3 3827 3634.8 4465.8 4181.7 6526.2 5559.2 2593.4 4268.5 3719.1 TRUE FALSE FALSE 4248.152437 4157.788827 3769.508885 4447.321703 4131.835959 5172.592555 5715.17619 3384.115721 3800.256229 3848.338448 1.103892626 1.080411425 0.979515949 1.155647239 1.07366751 1.344110614 1.485102277 0.879370608 0.98750572 1 11.91001997 -5.34062761 6.669752814 1.056290735 1.260533719 0.227864192 0.15146906 0.224346936 15.84693247 0.019872906 0.044826881 4.56E-06 5.34062761 0.204242984 SPY(ph)HVRGPINQVCSEILLS(ph)RMCANK ddPTM_HeLa_Curcumin_4h_R1 1 SPYHVRGPINQVCSEILLSRMCANK 25 2 A4D0V7 A4D0V7 CPED1 Cadherin-like and PC-esterase domain-containing protein 1 2 0 S(0.444)PY(0.555)HVRGPINQVCS(0.004)EILLS(0.997)RMCANK 46.971 0.0074699 0 853.23 580.38 921.94 874.82 587.93 721.51 700.59 949.81 764.65 797.44 TRUE FALSE FALSE 785.6959452 630.5454611 956.1079074 871.2002266 580.9193187 571.8606929 720.2466699 1239.402697 680.7698081 825.1509806 0.952184465 0.764157682 1.158706624 1.055807055 0.704015789 0.693037646 0.872866526 1.502031417 0.82502454 1 9.688514308 SPYGGGRPGR ddPTM_HeLa_Curcumin_4h_R1 2 SPYGGGRPGR 10 1 P46781 P46781 RPS9 40S ribosomal protein S9 0 0 ; ; 93.111 0.0085281 10962300 2074.28 2125.7 1566.59 1814.19 1792.73 2140.13 1359.14 1781.93 2052.03 1752.22 FALSE FALSE TRUE 1910.098549 2309.436036 1624.649204 1806.683362 1771.352866 1696.242914 1397.27381 2325.232254 1826.927443 1813.109515 1.053493203 1.273743267 0.896056852 0.996455729 0.976969594 0.935543551 0.770650531 1.282455492 1.007621122 1 10.82425035 SPYQEFTDHLVK ddPTM_HeLa_Curcumin_4h_R1 3 SPYQEFTDHLVK 12 0 P15880;H0YEN5;E9PQD7 P15880 RPS2 40S ribosomal protein S2 0 0 ;; ;; 133.05 0.00010097 24451700 9304.5 7349.1 7652.5 8040.4 8324.7 10609.5 7757 7448.8 9007.1 7880.3 FALSE FALSE TRUE 8568.039007 7984.323457 7936.108382 8007.130955 8225.43339 8408.970106 7974.640543 9719.90483 8019.043665 8154.139838 1.050759391 0.979174213 0.973261256 0.981971258 1.008743234 1.031251643 0.977986728 1.192020866 0.983432198 1 12.99331698 -4.254692769 24.99295257 1.012420593 1.192020948 0.808210875 0.02753947 297.1827934 1100890.596 0.004322756 0.056250726 5.56E-05 4.254692769 0.179600354 SQSGT(ph)LDGESAAWSASGEDSR ddPTM_HeLa_Curcumin_4h_R1 2 SQSGTLDGESAAWSASGEDSR 21 0 H3BMQ0;A0A2R8YDR3;A0A2R8Y7X5;P49815-3;P49815-5;A0A2R8Y6C9;A0A2R8Y5F1;P49815;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDZ2;A0A2R8YGU4;X5D2U8;P49815-2;P49815-6;P49815-7;P49815-4;H3BQK4 H3BMQ0 TSC2 Tuberin 1 0 SQS(0.207)GT(0.793)LDGESAAWSASGEDSR;S(0.005)QS(0.065)GT(0.883)LDGES(0.047)AAWS(0.001)ASGEDSR ; 329.52 3.15E-138 69614000 2820 2351.5 2370.5 2582.5 2159.02 2743.5 1484.51 925.12 2765.3 2852.4 TRUE FALSE FALSE 2596.794024 2554.753182 2458.352815 2571.814299 2133.275097 2174.467174 1526.161355 1207.184829 2461.953508 2951.520688 0.879815627 0.865571836 0.832910583 0.871352286 0.722771521 0.736727743 0.517076286 0.40900436 0.834130528 1 11.52724274 -4.182746886 0.406941639 0.956726223 3.88E-15 0.88655824 0.057353725 1.003562842 0.107545138 0.013210899 0.471925941 6.57E-05 4.182746886 -0.956726223 down SQAFIEMETR ddPTM_HeLa_Curcumin_4h_R1 1 SQAFIEMETR 10 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2;H0Y8T4 A0A0R4J2E8 MATR3 Matrin-3 0 0 105.4 0.0067472 1667400 548.57 561.26 443.46 731.63 778.95 671.43 694.65 606.63 799.8 601.18 FALSE FALSE TRUE 505.1501057 609.7728135 459.8950177 728.6027089 769.66153 532.1678494 714.1400094 791.5886944 712.063941 622.0709603 0.812045792 0.980230315 0.739296715 1.171253371 1.237256807 0.855477724 1.148004095 1.272505462 1.144666745 1 9.280935349 -6.240521499 24.96316625 0.90353717 1.127457292 0.306058814 0.147676698 619.4114083 739198.7789 0.019950605 0.033061171 5.75E-07 6.240521499 0.223920121 SQALGQS(ph)APSLTASLK ddPTM_HeLa_Curcumin_4h_R1 1 SQALGQSAPSLTASLK 16 0 O15021;H7C0U3;H7C2V7;H7C3S4;E7EX28;O15021-4 O15021 MAST4 Microtubule-associated serine/threonine-protein kinase 4 1 0 SQALGQS(0.935)APS(0.059)LT(0.006)ASLK 190.23 4.21E-07 20823000 2755.8 2342.2 2165.8 2783.3 2317.6 3107.9 2044.1 1954.8 2502.5 2303.9 TRUE FALSE FALSE 2537.675522 2544.649331 2246.066453 2771.783442 2289.964134 2463.286507 2101.451945 2550.809521 2227.982011 2383.960354 1.064478911 1.067404216 0.942157637 1.162680175 0.9605714 1.033274947 0.88149618 1.069988231 0.934571755 1 11.21914453 SQALGQSAPS(ph)LTASLK ddPTM_HeLa_Curcumin_4h_R1 1 SQALGQSAPSLTASLK 16 0 O15021;H7C0U3;H7C2V7;H7C3S4;E7EX28;O15021-4 O15021 MAST4 Microtubule-associated serine/threonine-protein kinase 4 1 0 S(0.002)QALGQS(0.336)APS(0.631)LT(0.03)ASLK 140.46 0.00039429 24120000 3141.5 2628.4 2806.6 2860.5 2983.5 4015.8 2587.7 2164.4 3539.7 3048 TRUE FALSE FALSE 2892.84696 2855.587184 2910.615065 2848.664009 2947.923711 3182.877813 2660.303898 2824.315596 3151.403766 3153.917773 0.917223329 0.905409522 0.922856991 0.903214419 0.934686293 1.009182243 0.843491837 0.895494366 0.999202894 1 11.62292933 -9.141357952 0.675067906 1.006831109 0.916192075 0.420407719 0.038891614 0.73235801 0.540405501 0.038115717 0.008465761 7.22E-10 9.141357952 -0.090639033 ASSPS(ph)PLTIGTPESQR ddPTM_HeLa_Curcumin_4h_R1 1 ASSPSPLTIGTPESQR 16 0 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 0 ASSPS(1)PLTIGTPESQR 310.17 6.38E-96 67140000 1776 1344.9 1932.8 1701.3 1914.6 1953.7 1430.9 418.36 1617.3 1772.2 TRUE FALSE FALSE 1635.427726 1461.147163 2004.431268 1694.260471 1891.769645 1548.480597 1471.047203 545.9160381 1439.886236 1833.783818 0.891832347 0.796793574 1.093057561 0.923915052 1.031620863 0.844418291 0.80219227 0.297699234 0.785199554 1 10.84060786 -4.180893249 1.730899725 0.947823819 1.26E-13 0.789781431 0.095742118 0.314220607 0.781216845 0.011598009 0.521020086 6.59E-05 4.180893249 -0.947823819 down SQAPLES(ph)SLDSLGDVFLDSGRK ddPTM_HeLa_Curcumin_4h_R1 3 SQAPLESSLDSLGDVFLDSGRK 22 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 S(0.002)QAPLES(0.496)S(0.496)LDS(0.006)LGDVFLDSGRK;S(0.01)QAPLES(0.472)S(0.472)LDS(0.045)LGDVFLDSGRK;S(0.007)QAPLES(0.493)S(0.493)LDS(0.007)LGDVFLDSGRK ;; 86.701 0.00024268 28961000 3110.22 2354.18 2680.79 2518.97 2149.29 3509.26 2534.62 1488.68 3320.62 2328.41 TRUE FALSE FALSE 2864.042805 2557.664829 2780.142436 2508.54717 2123.66112 2781.399918 2605.734616 1942.571679 2956.356294 2409.322074 1.188733891 1.06157033 1.153910665 1.041183824 0.881435132 1.154432588 1.081521912 0.806273142 1.227049022 1 11.23441155 -6.002390712 24.96379413 1.093485173 0.995597613 0.252224278 0.110367231 143.3583251 1496979.952 0.016404542 0.029386773 9.95E-07 6.002390712 -0.09788756 SQAQQPQKEAALS(ph)S ddPTM_HeLa_Curcumin_4h_R1 2 SQAQQPQKEAALSS 14 1 Q3MHD2-2;Q3MHD2 Q3MHD2-2 LSM12 Protein LSM12 homolog 1 0 SQAQQPQKEAALS(0.601)S(0.399);SQAQQPQKEAALS(0.597)S(0.403) ; 137.39 0.00812 12911200 6915.1 4000.3 3017.53 5284.57 2044.96 6397.1 3667.47 4351.34 9895.5 7893.4 TRUE FALSE FALSE 6367.762538 4346.068107 3129.362316 5262.70385 2020.575188 5070.26935 3770.369338 5678.043535 8809.988407 8167.695062 0.77962785 0.532104599 0.383138975 0.644331578 0.247386218 0.620771137 0.461619748 0.695183095 1.078638262 1 12.99571329 -7.607555354 1.117604909 0.940731983 0.497787821 0.68816682 0.137731166 0.171728766 0.439408462 0.028876847 0.029022551 2.47E-08 7.607555354 -0.442944163 SQASMVINSDT(ph)DDEEEVSAALTLAHLK ddPTM_HeLa_Curcumin_4h_R1 1 SQASMVINSDTDDEEEVSAALTLAHLK 27 0 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 SQAS(0.001)MVINS(0.246)DT(0.753)DDEEEVSAALTLAHLK 97.059 3.69E-06 3240300 583.5 310.44 542.16 759.22 674.45 710.47 574.32 450.65 561.95 526.92 TRUE FALSE FALSE 537.3153593 337.2730503 562.2529265 756.0785488 666.4076242 563.1105134 590.4338735 588.0511105 500.3054909 545.2304308 0.985483071 0.618588089 1.031220737 1.386713775 1.222249505 1.032793626 1.082907043 1.078536848 0.917603756 1 9.090722275 -6.513254635 24.99178941 0.958196873 1.158274362 0.424763688 0.142665717 451.4578424 1172341.753 0.023095903 0.033772541 3.07E-07 6.513254635 0.200077489 SQASPS(ph)EDEETFELR ddPTM_HeLa_Curcumin_4h_R1 2 SQASPSEDEETFELR 15 0 Q13829-2;Q13829 Q13829-2 TNFAIP1 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 1 0 SQAS(0.047)PS(0.952)EDEET(0.002)FELR;SQAS(0.031)PS(0.969)EDEETFELR ; 151.31 9.43E-07 0 2024.12 1854.09 2117.11 2089.7 2049.3 1761.35 1226.32 733.28 1964.74 1894.46 TRUE FALSE FALSE 1863.908766 2014.349278 2195.571959 2081.053375 2024.863436 1396.026155 1260.727239 956.8536964 1749.212938 1960.292344 0.950832039 1.027575955 1.120022718 1.061603582 1.032939522 0.712152021 0.643132257 0.488117856 0.892322486 1 10.93685311 -5.032026806 2.232775761 1.001474731 0.552274159 0.878307941 0.069025576 0.075721629 0.73092254 0.009901958 0.036502604 9.29E-06 5.032026806 -0.449200571 SQAVEKPPSEK(ac)PR ddPTM_HeLa_Curcumin_4h_R1 1 SQAVEKPPSEKPR 13 2 A0A0M3HER2;Q7Z7K6-3;Q7Z7K6 A0A0M3HER2 CENPV Centromere protein V 0 1 SQAVEKPPSEK(1)PR 132.79 0.00026011 3287400 1063.2 1030.4 1089 1208.5 1136.5 1199 1129.8 1092.6 1852.4 1326.5 FALSE TRUE FALSE 979.0465981 1119.463185 1129.359298 1203.499547 1122.94798 950.3138845 1161.499147 1425.72871 1649.196354 1372.595776 0.71328108 0.815581108 0.822790888 0.876805516 0.818119944 0.692347959 0.846206267 1.038709819 1.201516414 1 10.42269111 -9.544540936 1.321254752 0.999605409 0.810973849 0.422924969 0.112241325 0.387917428 1.21706485 0.064882999 0.01553965 2.85E-10 9.544540936 -0.18863156 SQDADS(ph)PGSSGAPENLTFK ddPTM_HeLa_Curcumin_4h_R1 3 SQDADSPGSSGAPENLTFK 19 0 A8MQ02;J3KN01;P55196-3;P55196;P55196-5;H0Y8U8;H0Y948;H0Y8L4 A8MQ02 MLLT4 Afadin 1 0 SQDADS(0.997)PGS(0.002)S(0.001)GAPENLTFK;S(0.044)QDADS(0.955)PGS(0.001)SGAPENLTFK;S(0.002)QDADS(0.476)PGS(0.415)S(0.108)GAPENLTFK ;; 201.48 2.74E-13 21705900 8576.5 7246.2 7875.2 8525 7881.8 9303.3 7562.1 7451.7 8189.2 6919.3 TRUE FALSE FALSE 7897.660975 7872.52924 8167.06184 8489.725809 7787.814683 7373.69071 7774.272174 9723.689027 7290.865248 7159.74516 1.103064536 1.099554392 1.140691695 1.185758099 1.087722329 1.029881727 1.08583085 1.358105465 1.018313513 1 12.80569252 -13.52283462 0.024350462 3.83E-06 1.863872689 0.364919006 0.078241376 1532.988244 3.005444891 161.7179505 81.29369636 3.00E-14 13.52283462 1.863868861 SQDAT(ph)FSPGSEQAEK ddPTM_HeLa_Curcumin_4h_R1 2 SQDATFSPGSEQAEK 15 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 S(0.002)QDAT(0.665)FS(0.274)PGS(0.059)EQAEK;S(0.003)QDAT(0.996)FS(0.002)PGSEQAEK ; 168.68 0.00055642 128850000 3246.1 3635.1 2842 3487.1 2729.7 3751.1 2751.5 2509.3 3452 3624.6 TRUE FALSE FALSE 2989.16776 3949.301846 2947.32702 3472.671304 2697.15011 2973.079576 2828.699685 3274.374019 3073.324236 3750.55458 0.796993537 1.052991434 0.785837656 0.92590875 0.719133678 0.792703989 0.754208378 0.873037293 0.819431946 1 11.87288822 -5.774466916 24.98226743 0.905810972 0.783154452 0.276181134 0.088170529 227.2104123 435710.3061 0.014186301 0.025830441 1.68E-06 5.774466916 -0.122656519 SQDATFS(ph)PGS(ph)EQAEKSPGPIVSR ddPTM_HeLa_Curcumin_4h_R1 1 SQDATFSPGSEQAEKSPGPIVSR 23 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 2 0 S(0.001)QDAT(0.029)FS(0.972)PGS(0.994)EQAEKS(0.004)PGPIVSR 73.796 0.00088922 69143000 3449.6 2652.8 2874.4 2792.1 2631 3544.1 2861.7 2947.7 3705.6 2811.4 TRUE FALSE FALSE 3176.56052 2882.096211 2980.927793 2780.54703 2599.627043 2809.01371 2941.9916 3846.44016 3299.104951 2909.095941 1.09194079 0.990718859 1.024692156 0.955811388 0.893620251 0.965596793 1.011307863 1.322211518 1.134065365 1 11.50635516 -4.260782644 23.97371473 1.016843589 1.322211688 0.677905407 0.064787455 14.46906011 527966.675 0.009203622 0.073506634 5.49E-05 4.260782644 0.305368099 SQDATFS(ph)PGSEQAEK ddPTM_HeLa_Curcumin_4h_R1 1 SQDATFSPGSEQAEK 15 0 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 SQDAT(0.35)FS(0.602)PGS(0.047)EQAEK 231.37 5.77E-21 6594700 2126.9 1852.6 2008.3 2321 2235.4 2341 1739.1 1139.5 1965.4 1915.7 TRUE FALSE FALSE 1958.553621 2012.730489 2082.729365 2311.396317 2208.744315 1855.450211 1787.894465 1486.928304 1749.800537 1982.270432 0.988035532 1.015366247 1.050678722 1.166034805 1.114249741 0.936022745 0.90194276 0.750113748 0.882725439 1 10.95293808 -4.48883629 1.737060944 1.019216412 0.726523501 0.570774356 0.07460611 0.315924263 1.299324902 0.01007493 0.131261501 3.24E-05 4.48883629 -0.292692911 SQDATFS(ph)PGSEQAEKS(ph)PGPIVSR ddPTM_HeLa_Curcumin_4h_R1 1 SQDATFSPGSEQAEKSPGPIVSR 23 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 2 0 S(0.005)QDAT(0.13)FS(0.851)PGS(0.042)EQAEKS(0.965)PGPIVS(0.006)R 76.749 0.00060268 93651000 4991.5 3950.7 4258.8 4477.9 4125.4 4680.1 3793.7 4444 4790.4 3811.6 TRUE FALSE FALSE 4596.417508 4292.180904 4416.634874 4459.371636 4076.207299 3709.394504 3900.141012 5798.955142 4264.905105 3944.052816 1.165404654 1.088266589 1.119821432 1.13065718 1.03350728 0.940503253 0.988866324 1.470303622 1.081350911 1 11.94546316 -9.527928921 1.286813933 1.000022895 1.111107889 0.033635001 0.13741356 0.942326025 2.794911667 0.0911753 0.021836424 2.97E-10 9.527928921 0.111084994 SQDATFSPGSEQAEKS(ph)PGPIVSR ddPTM_HeLa_Curcumin_4h_R1 2 SQDATFSPGSEQAEKSPGPIVSR 23 1 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 SQDAT(0.001)FS(0.044)PGS(0.013)EQAEKS(0.926)PGPIVS(0.016)R;SQDATFSPGS(0.008)EQAEKS(0.985)PGPIVS(0.007)R ; 75.939 0.00040874 267381000 3282 2494.4 2450.9 3008.2 2959.8 3825.2 2891.5 4773.8 3252.6 3110.1 TRUE FALSE FALSE 3022.226237 2710.004821 2541.73251 2995.752865 2924.506318 3031.810401 2972.627708 6229.309644 2895.797918 3218.175744 0.93911162 0.842093483 0.789805378 0.930885416 0.908746616 0.942089756 0.923699619 1.935664843 0.89982591 1 11.6520274 -4.260911647 24.97806361 0.938826501 1.935665149 0.961162928 0.061672714 6.810269938 322247.6117 0.010088017 0.08016118 5.48E-05 4.260911647 0.996838648 RES(ph)EALDSPNSK ddPTM_HeLa_Curcumin_4h_R1 2 RESEALDSPNSK 12 1 P0C7T5 P0C7T5 ATXN1L Ataxin-1-like 1 0 RES(1)EALDSPNSK;RES(1)EALDSPNSK ; 73.593 0.015211 22791000 4255.1 3463.4 4169.4 3716.8 4704 6224.4 6979.2 9488.1 3887.4 3655.8 TRUE FALSE FALSE 3918.304345 3762.760863 4323.921632 3701.420866 4647.907872 4933.389277 7175.017568 12380.97801 3460.961946 3782.838778 1.035810558 0.994692368 1.143036192 0.978477034 1.228682517 1.304150022 1.896728354 3.272933038 0.9149113 1 11.88525358 -3.745278464 0.980197967 1.023015217 7.320581494 0.989654427 0.06990715 0.244712846 0.089878307 0.008725257 2.074207267 0.000179772 3.745278464 6.297566278 up SQDQDS(ph)EVNELSR ddPTM_HeLa_Curcumin_4h_R1 2 SQDQDSEVNELSR 13 0 E7ERS3;Q86VM9 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 0 SQDQDS(1)EVNELSR;SQDQDS(0.52)EVNELS(0.48)R ; 191.15 7.48E-06 28438000 3654.8 3394.5 3465.8 3197.6 3963.6 4153.3 3559.2 3792.1 3019.1 3369.2 TRUE FALSE FALSE 3365.518723 3687.905454 3594.245597 3184.369178 3916.336659 3291.858763 3659.061573 4948.293833 2687.912283 3486.279449 0.965361146 1.057834149 1.030968874 0.913400439 1.123357068 0.944232615 1.049560606 1.419362362 0.770997369 1 11.7674725 -4.26752876 3.620146236 0.994753504 1.464659295 0.67749842 0.090600936 0.071036463 1.685188202 0.007186297 0.089197978 5.40E-05 4.26752876 0.469905791 SQDSMSSDTAR ddPTM_HeLa_Curcumin_4h_R1 3 SQDSMSSDTAR 11 0 P25205;P25205-2;J3KQ69;A0A499FHX9;Q7Z6P5 P25205 MCM3 DNA replication licensing factor MCM3 0 0 ;; ;; 150.04 6.41E-06 1348400 2778.54 2512.82 2827.67 2623.13 1917.7 2315.27 1739.76 1798.25 2712.97 2674.17 FALSE FALSE TRUE 2558.615627 2730.016964 2932.465938 2612.276183 1894.83268 1835.056904 1788.572983 2346.528147 2415.363979 2767.097208 0.924656936 0.986599587 1.05976253 0.9440493 0.684772719 0.663170379 0.646371576 0.848010738 0.872887288 1 11.43415761 -5.792423377 5.948860924 0.972843788 0.702078341 0.765070004 0.068901693 0.054102917 5.435923919 0.009233631 0.01725139 1.61E-06 5.792423377 -0.270765448 SQDSVSSPS(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 1 SQDSVSSPSPQK 12 0 I3L4X5;Q70CQ4 I3L4X5 USP31 Ubiquitin carboxyl-terminal hydrolase 31 1 0 SQDS(0.01)VS(0.052)S(0.165)PS(0.772)PQK 104.95 0.0073221 0 1267.6 1549.8 1275.8 1388 1488.8 1342.9 919.57 474.82 1635 1150.5 TRUE FALSE FALSE 1167.268122 1683.757806 1323.08227 1382.256824 1471.047032 1064.367402 945.3706593 619.5904322 1455.644591 1190.479789 0.980502259 1.414352282 1.111385747 1.161092222 1.235675772 0.894065915 0.794108953 0.52045439 1.22273776 1 10.21732741 -4.555882252 1.750053186 1.05845763 0.494400564 0.623285033 0.148828685 0.312015207 1.412785685 0.022624202 0.24083875 2.78E-05 4.555882252 -0.564057066 SQDSYPGS(ph)PS(ph)LSPR ddPTM_HeLa_Curcumin_4h_R1 1 SQDSYPGSPSLSPR 14 0 A0A0D9SEU5;R4GMX8;Q6VN20-2;Q6VN20-3;Q6VN20 A0A0D9SEU5 RANBP10 Ran-binding protein 10 2 0 SQDS(0.107)Y(0.007)PGS(0.885)PS(0.652)LS(0.349)PR 181.69 0.00025624 31826000 6683.2 5345.6 5870.5 6378 6150.7 6770.4 4346.5 3146.1 6595.6 5421.2 TRUE FALSE FALSE 6154.217668 5807.649844 6088.065894 6351.609526 6077.35692 5366.142722 4468.451092 4105.331407 5872.079181 5609.586296 1.097089401 1.035308049 1.085296771 1.13227771 1.083387722 0.956602223 0.796574089 0.731842099 1.046793626 1 12.45367866 -4.823989745 2.309823041 1.057679895 0.739630588 0.916639437 0.036479913 0.079632345 0.820820837 0.006892182 0.03215039 1.50E-05 4.823989745 -0.318049307 SQDSYPGS(ph)PSLS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SQDSYPGSPSLSPR 14 0 A0A0D9SEU5;R4GMX8;Q6VN20-2;Q6VN20-3;Q6VN20 A0A0D9SEU5 RANBP10 Ran-binding protein 10 2 0 S(0.081)QDS(0.029)YPGS(0.883)PS(0.018)LS(0.989)PR 163.34 0.00055656 36189000 4808.8 3941.8 3834.7 4228.6 4408.6 4522 3326.6 2417.5 4606.3 3875.2 TRUE FALSE FALSE 4428.178406 4282.511628 3976.817355 4211.103174 4356.030324 3584.086227 3419.935443 3154.584621 4101.000414 4009.862912 1.104321645 1.067994523 0.991758931 1.05018632 1.086328989 0.893817646 0.852880889 0.786706352 1.022728334 1 11.9693372 -5.064213206 2.788383081 1.049609723 0.820421574 0.860284126 0.037828572 0.084618679 1.282286923 0.006738569 0.021604729 8.63E-06 5.064213206 -0.229188149 PVSVAGSPLS(ph)PGPVR ddPTM_HeLa_Curcumin_4h_R1 2 PVSVAGSPLSPGPVR 15 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 PVS(0.002)VAGSPLS(0.998)PGPVR;PVSVAGSPLS(1)PGPVR ; 227.92 9.06E-21 101587000 5330 4699 4550.9 4546.6 4975.4 5072 3379.6 1370.42 3624.3 4261.5 TRUE FALSE FALSE 4908.124876 5105.160622 4719.560357 4527.787374 4916.071605 4020.010027 3474.42248 1788.254749 3226.723358 4409.586808 1.113057774 1.157741268 1.070295373 1.026805361 1.114859922 0.911652316 0.787924727 0.40553794 0.731751862 1 12.10642776 -4.1803406 1.146430176 1.066250015 0.00379271 0.719566118 0.117025562 0.355757121 0.335014636 0.009064507 0.47214447 6.60E-05 4.1803406 -1.062457305 down SQDVAVS(ph)PQQQQCSK ddPTM_HeLa_Curcumin_4h_R1 3 SQDVAVSPQQQQCSK 15 0 H3BQ37;H3BPW9;Q96F86;H3BTD6 H3BQ37 EDC3 Enhancer of mRNA-decapping protein 3 1 0 SQDVAVS(1)PQQQQCSK;SQDVAVS(1)PQQQQCSK;S(0.008)QDVAVS(0.992)PQQQQCSK ;; 300.56 4.05E-92 454263000 16747.2 13444.2 15286.3 14733.3 15368.4 17166.7 11985.1 5492.4 16739.6 13240.4 TRUE FALSE FALSE 15421.64145 14606.25674 15852.82373 14672.33751 15185.14187 13606.13291 12321.36965 7167.007476 14903.30776 13700.50291 1.125625938 1.066110991 1.157097942 1.070934228 1.108363829 0.993111931 0.899337034 0.523120029 1.087792751 1 13.74194123 -4.099796651 1.376214439 1.072030166 0.122897234 0.937564192 0.043767492 0.401933342 0.503060293 0.008294268 0.584941696 7.95E-05 4.099796651 -0.949132932 SQEADVQDWEFR ddPTM_HeLa_Curcumin_4h_R1 1 SQEADVQDWEFR 12 0 Q9C0C2;Q9C0C2-2;A0A2R8Y5C4 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 0 0 168.98 0.0010916 7755200 2195.6 2029 2051.5 1417.1 1767.6 2234.6 1563.1 513.05 2135.9 2094.2 FALSE FALSE TRUE 2021.815943 2204.377719 2127.530395 1411.236416 1746.522524 1771.118771 1606.956379 669.4765832 1901.597114 2166.973294 0.933013779 1.017261138 0.981798161 0.651247719 0.805973257 0.817323765 0.741567228 0.30894547 0.877536017 1 11.08146566 -4.058443768 0.4899629 0.974045509 1.84E-18 0.699328581 0.110915056 2.026253368 0.283851516 0.022557548 1.183888048 8.74E-05 4.058443768 -0.974045509 SQEDEIS(ph)SPVNK ddPTM_HeLa_Curcumin_4h_R1 2 SQEDEISSPVNK 12 0 Q5UIP0-2;Q5UIP0;H7C2B5 Q5UIP0-2 RIF1 Telomere-associated protein RIF1 1 0 SQEDEIS(0.5)S(0.5)PVNK;SQEDEIS(0.5)S(0.5)PVNK ; 214.48 3.72E-13 144307000 16263.7 12946.9 14499.2 15465.6 14505 18571.5 15740.5 4481.2 17084.4 15575.8 TRUE FALSE FALSE 14976.41098 14065.97235 15036.55311 15401.60745 14332.03735 14719.56156 16182.13607 5847.497251 15210.28406 16117.05789 0.929227349 0.872738216 0.932958931 0.955609116 0.889246502 0.913290853 1.004037845 0.362814187 0.943738253 1 13.97630079 -4.258225907 24.99997784 0.949893008 0.36281397 0.945147328 0.041469694 54.70461488 425567.0046 0.006679821 0.063763066 5.52E-05 4.258225907 -0.587079038 SQEDEISS(ph)PVNK ddPTM_HeLa_Curcumin_4h_R1 2 SQEDEISSPVNK 12 0 Q5UIP0-2;Q5UIP0;H7C2B5 Q5UIP0-2 RIF1 Telomere-associated protein RIF1 1 0 SQEDEIS(0.046)S(0.954)PVNK;SQEDEIS(0.155)S(0.845)PVNK ; 145 0.0008826 138203000 17699.3 13981.3 16348.1 18425.3 16555.9 21964 17800.2 5501.7 20002.1 18190.1 TRUE FALSE FALSE 16298.38173 15189.78127 16953.97497 18349.06099 16358.48171 17408.41881 18299.62571 7179.143003 17807.91967 18822.20462 0.865912472 0.807013927 0.900743314 0.974862475 0.869105508 0.924887343 0.972236041 0.381418816 0.94611232 1 14.200148 -4.258305987 24.99350823 0.923493051 0.381418616 0.890725784 0.05633832 81.33134001 648707.1996 0.00941961 0.08978491 5.52E-05 4.258305987 -0.542074435 SQEEPKDT(ph)FEHDPSESIDEFNK ddPTM_HeLa_Curcumin_4h_R1 1 SQEEPKDTFEHDPSESIDEFNK 22 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 S(0.247)QEEPKDT(0.753)FEHDPSESIDEFNK 69.152 0.0008947 85698000 4634.6 4095.1 4337.3 3860.1 5502.1 5707.5 4957.5 4610.2 3933.5 3867.6 TRUE FALSE FALSE 4267.76652 4449.062197 4498.044153 3844.127929 5436.491051 4523.700163 5096.594108 6015.828757 3502.004891 4001.998812 1.066408742 1.111710024 1.123949397 0.960551992 1.358443944 1.130360196 1.273512149 1.503206033 0.875063951 1 11.96650502 -1 0.336667512 1.021834588 5.870899891 0.678809905 0.102330065 19.77209781 0.250040765 0.025857529 60.8835795 0.1 1 4.849065303 GAPSS(ph)PATGVLPS(ph)PQGK ddPTM_HeLa_Curcumin_4h_R1 1 GAPSSPATGVLPSPQGK 17 0 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 2 0 GAPS(0.129)S(0.802)PAT(0.071)GVLPS(0.999)PQGK 110.32 0.0027669 8077200 2116 1809.6 2042.6 2033.8 1983.7 3207.7 2973.9 3869 2574.2 1929 TRUE FALSE FALSE 1948.516367 1966.013761 2118.300553 2025.384674 1960.045673 2542.386862 3057.33963 5048.640289 2291.8167 1996.032606 0.976194658 0.984960744 1.061255486 1.014705205 0.981970769 1.273720105 1.53170826 2.529337584 1.148186003 1 10.96291957 -3.732407612 0.998127984 0.991062898 5.390320413 0.978957042 0.0664367 0.270525841 0.100366025 0.006400574 1.644746645 0.000185179 3.732407612 4.399257515 up SQEES(ph)PPGSTK ddPTM_HeLa_Curcumin_4h_R1 1 SQEESPPGSTK 11 0 P30304-2;P30304 P30304-2 CDC25A M-phase inducer phosphatase 1 1 0 S(0.003)QEES(0.983)PPGS(0.012)T(0.002)K 102.52 0.009552 4742800 2878.1 2578.8 2316.7 2275.5 2808.2 3335.1 1946.4 1078.5 2690.2 2417.5 TRUE FALSE FALSE 2650.295348 2801.699981 2402.55894 2266.084584 2774.714049 2643.362666 2001.010746 1407.329685 2395.091791 2501.507945 1.059479085 1.12000443 0.960444257 0.905887422 1.109216565 1.056707683 0.799921803 0.562592531 0.957459198 1 11.28858232 -4.490879159 2.597430502 1.029077561 0.55575666 0.8251123 0.066746678 0.091490214 1.048043546 0.009109481 0.074547499 3.23E-05 4.490879159 -0.473320901 SQESGYYDR ddPTM_HeLa_Curcumin_4h_R1 1 SQESGYYDR 9 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 0 109.44 0.0038047 3345200 1484.2 1351.2 1133.1 1213.5 1628.9 1421.8 1373.7 952.98 1478.4 1404.4 FALSE FALSE TRUE 1366.724004 1467.991707 1175.093683 1208.478859 1609.476431 1126.902653 1412.242325 1243.539215 1316.223219 1453.202795 0.940490899 1.010176771 0.808623329 0.831596844 1.10753739 0.775461385 0.971813658 0.85572311 0.905739531 1 10.50502033 -8.079720358 0.407798317 1.005542308 0.897853125 0.012233047 0.09851184 1.770366426 0.724821914 0.07832387 0.041881516 8.32E-09 8.079720358 -0.107689183 KDESFLGK(ac)LGGTLAR ddPTM_HeLa_Curcumin_4h_R1 1 KDESFLGKLGGTLAR 15 2 Q9HBI1 Q9HBI1 PARVB Beta-parvin 0 1 KDESFLGK(1)LGGTLAR 115.38 0.00012182 908370 527.97 501.78 706.33 474.21 565.7 889.08 721.44 1054.5 643.45 496.66 FALSE TRUE FALSE 486.1806174 545.1516273 732.5072112 472.2478447 558.954397 704.674786 741.6816647 1376.012196 572.8651448 513.918898 0.946025957 1.060773654 1.425336204 0.918915118 1.087631529 1.371178971 1.443188152 2.677488999 1.114699512 1 9.005396894 -1.463161476 0.819283237 1.00985862 200 0.900722639 0.155503612 44.2489107 0.314289676 0.023873961 16132.9066 0.034422192 1.463161476 198.9901414 up SQGDEAGGHGEDRPEPLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SQGDEAGGHGEDRPEPLSPK 20 1 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 0 SQGDEAGGHGEDRPEPLS(1)PK;SQGDEAGGHGEDRPEPLS(1)PK ; 46.461 0.018769 280910000 12068.1 10019.3 10251.9 9988.5 11441.3 13915.2 9863 8044.8 13329.9 10410 TRUE FALSE FALSE 11112.89715 10885.32365 10631.84443 9947.170234 11304.86997 11029.03066 10139.72924 10497.62249 11867.64332 10771.74673 1.031670855 1.010543965 0.987012107 0.923450067 1.049492739 1.023885071 0.941326369 0.974551552 1.101738058 1 13.39496459 -6.772172269 4.971260899 1.01517736 0.983356777 0.203087774 0.044107808 0.272640107 18.03187704 0.005751795 0.007852442 1.69E-07 6.772172269 -0.031820583 SQGS(ph)GNEAEPLGK ddPTM_HeLa_Curcumin_4h_R1 3 SQGSGNEAEPLGK 13 0 B8ZZZ7;Q9NUQ6;Q9NUQ6-4;Q9NUQ6-3;Q9NUQ6-2 B8ZZZ7 SPATS2L SPATS2-like protein 1 0 S(0.006)QGS(0.994)GNEAEPLGK;S(0.001)QGS(0.999)GNEAEPLGK;S(0.012)QGS(0.988)GNEAEPLGK ;; 154.81 0.0004 54450500 7051.5 4969.2 6380.1 6794.2 6528.9 6333.3 4956 2941.42 6410.3 6586.3 TRUE FALSE FALSE 6493.366334 5398.715506 6616.552119 6766.087401 6451.047132 5019.702189 5095.052022 3838.245417 5707.106128 6815.173435 0.952780791 0.792161132 0.970856014 0.992797537 0.946571235 0.736547974 0.747604162 0.563191158 0.837411723 1 12.73453466 -4.652404146 0.911417837 0.966022064 0.491233936 0.67318249 0.078039434 0.438960713 0.395086514 0.01100305 0.179599505 2.23E-05 4.652404146 -0.474788128 SQGS(ph)PEDSAPQASPGPSK ddPTM_HeLa_Curcumin_4h_R1 1 SQGSPEDSAPQASPGPSK 18 0 Q9P107;Q9P107-2 Q9P107 GMIP GEM-interacting protein 1 0 S(0.022)QGS(0.555)PEDS(0.288)APQAS(0.134)PGPSK 68.134 0.015968 16985000 2638.8 2335.4 2313.8 2754.6 2664 3144.4 1628.3 2505 2796.9 2967.7 TRUE FALSE FALSE 2429.936196 2537.26157 2399.551463 2743.202195 2632.23354 2492.215995 1673.985716 3268.762968 2490.087067 3070.827354 0.79129691 0.826246896 0.781402269 0.89331046 0.857174056 0.811578024 0.545125311 1.064456771 0.810884749 1 11.58441169 -9.282082805 0.77857091 1.013544537 0.812083569 0 0.133794562 0.820349118 0.797224212 0.105604126 0.022143405 5.22E-10 9.282082805 -0.201460968 SQGS(ph)PMDPMVMK ddPTM_HeLa_Curcumin_4h_R1 2 SQGSPMDPMVMK 12 0 A0A3F2YNW7;Q8NFD5;Q8NFD5-2;Q8NFD5-3;A0A1B0GUC6;A0A1B0GUG2;A0A1B0GU09;A0A6I8PTU7;H0Y7H8 A0A3F2YNW7 ARID1B AT-rich interactive domain-containing protein 1B 1 0 S(0.002)QGS(0.998)PMDPMVMK;S(0.004)QGS(0.996)PMDPMVMK ; 60.157 0.013568 14380600 5806.3 4594.7 4723.7 4799.7 5496.6 7196.3 7416.6 3806.8 5548.6 4251.4 TRUE FALSE FALSE 5346.725228 4991.845394 4898.764477 4779.840113 5431.056635 5703.706261 7624.689835 4967.475796 4939.932462 4399.135834 1.215403532 1.13473318 1.113574271 1.086540697 1.234573525 1.296551522 1.733224461 1.129193547 1.122932469 1 12.10300443 -1 0.139700471 0.9715098 2.562155745 0.281568621 0.163082271 60.54137911 0.559155129 0.433783753 19.29997368 0.1 1 1.590645945 S(ph)VAVSDEEEVEEEAER ddPTM_HeLa_Curcumin_4h_R1 2 SVAVSDEEEVEEEAER 16 0 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 0 S(0.512)VAVS(0.488)DEEEVEEEAER;S(0.641)VAVS(0.359)DEEEVEEEAER ; 215.48 3.78E-15 88466000 6463.1 6245 6321.7 6309.8 6504 6900.3 4761.4 1688.58 7054.3 6159.7 TRUE FALSE FALSE 5951.538815 6784.789973 6555.987763 6283.691719 6426.444048 5469.099998 4894.992069 2203.420269 6280.460939 6373.749117 0.933757935 1.064489651 1.028592065 0.985870577 1.008267494 0.858066406 0.767992586 0.345702385 0.985363688 1 12.63792652 -4.180102913 1.310638728 0.982906885 7.91E-22 0.956293995 0.042201984 0.256797118 0.328984773 0.006979983 0.352874283 6.61E-05 4.180102913 -0.982906885 down SQHVNGGVMNGLEQSEEVGQGMPLVS(ph)EGDRGSPFQEEEGSALK ddPTM_HeLa_Curcumin_4h_R1 1 SQHVNGGVMNGLEQSEEVGQGMPLVSEGDRGSPFQEEEGSALK 43 1 P48681 P48681 NES Nestin 1 0 SQHVNGGVMNGLEQS(0.011)EEVGQGMPLVS(0.638)EGDRGS(0.322)PFQEEEGS(0.029)ALK 47.5 0.0014072 12020000 939.39 869.22 663.7 812.56 976.68 1193.2 618.57 552.68 1124.5 757.61 TRUE FALSE FALSE 865.0362903 944.3515036 688.2973058 809.197842 965.0337289 945.7168699 635.9254094 721.1895878 1001.145163 783.9368911 1.103451439 1.204626947 0.878000913 1.032223194 1.23100946 1.206368626 0.811194647 0.919958731 1.277073671 1 9.614593708 -4.746393783 24.99992235 1.069012038 0.865576618 0.345753859 0.125097299 201.0604349 334078.3463 0.015225518 0.056500704 1.79E-05 4.746393783 -0.20343542 SQIDVALS(ph)QDS(ph)TYQGER ddPTM_HeLa_Curcumin_4h_R1 2 SQIDVALSQDSTYQGER 17 0 Q92900-2;Q92900 Q92900-2 UPF1 Regulator of nonsense transcripts 1 2 0 S(0.009)QIDVALS(0.992)QDS(0.98)T(0.018)Y(0.001)QGER;SQIDVALS(1)QDS(1)TYQGER ; 157.84 0.00038587 12722000 7028.2 6693 7146.1 8245.2 7862.7 10675.4 7336.5 5216.1 7519.2 8651.2 TRUE FALSE FALSE 6471.910554 7271.513097 7410.940752 8211.083547 7768.942438 8461.201703 7542.342445 6806.464878 6694.362572 8951.828556 0.722970789 0.812293606 0.827868933 0.917252101 0.86786095 0.945192555 0.842547687 0.760343525 0.747820686 1 13.12796669 -9.593578328 1.407938078 0.99936558 0.826790621 0 0.099466076 0.322616295 1.1539846 0.051838654 0.012214596 2.55E-10 9.593578328 -0.17257496 SQIDVALSQDS(ph)TYQGER ddPTM_HeLa_Curcumin_4h_R1 3 SQIDVALSQDSTYQGER 17 0 Q92900-2;Q92900 Q92900-2 UPF1 Regulator of nonsense transcripts 1 1 0 SQIDVALS(0.293)QDS(0.701)T(0.006)YQGER;SQIDVALS(0.322)QDS(0.678)T(0.001)YQGER;SQIDVALS(0.376)QDS(0.623)TYQGER ;; 242.67 1.69E-30 357962000 9206.9 7957.9 8225.08 8404.9 8804.3 10781.5 5957.65 3598.63 9635.2 7524.2 TRUE FALSE FALSE 8478.16415 8645.745416 8529.9087 8370.122751 8699.314473 8545.295367 6124.805625 4695.835721 8578.242666 7785.66539 1.088945353 1.110469688 1.095591484 1.075068389 1.11735016 1.097567766 0.786677223 0.603138651 1.101799556 1 12.92660463 -4.589574083 3.20083593 1.062389064 0.624654849 0.938648772 0.040772219 0.052916655 1.034473888 0.007378797 0.039083812 2.57E-05 4.589574083 -0.437734215 SQIHDIVLVGGSTR ddPTM_HeLa_Curcumin_4h_R1 3 SQIHDIVLVGGSTR 14 0 P11142;E9PKE3;E9PNE6;P11142-2;E9PN89;A8K7Q2 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 ;; ;; 83.823 0.0075407 40470200 9689 8516.2 7791.5 7335.2 11821.3 17460.1 9654.8 8645.3 12105.1 8210.6 FALSE FALSE TRUE 8922.105426 9252.302381 8080.259844 7304.848886 11680.33872 13838.67844 9925.687703 11281.21217 10777.20082 8495.917739 1.05016382 1.089029186 0.951075574 0.859806923 1.374817775 1.628862104 1.168289055 1.327839148 1.268515203 1 13.05255408 -5.745434971 24.99087987 1.013391436 1.378326965 0.565004953 0.144657309 103.8990763 162237.4449 0.01711632 0.034145584 1.80E-06 5.745434971 0.364935529 SQLDDHPES(ph)DDEENFIDANDDEDMEK ddPTM_HeLa_Curcumin_4h_R1 3 SQLDDHPESDDEENFIDANDDEDMEK 26 0 Q03701 Q03701 CEBPZ CCAAT/enhancer-binding protein zeta 1 0 S(0.001)QLDDHPES(0.999)DDEENFIDANDDEDMEK;S(0.015)QLDDHPES(0.985)DDEENFIDANDDEDMEK;S(0.001)QLDDHPES(0.999)DDEENFIDANDDEDMEK ;; 89.197 1.21E-05 22388300 3831.12 3985.66 3897.12 4021.98 4504.03 4314.44 3616.84 2259.65 3644.46 3563.11 TRUE FALSE FALSE 3527.882809 4330.162691 4041.550695 4005.338112 4450.322384 3419.57651 3718.318796 2948.606883 3244.671856 3686.927807 0.956862459 1.17446365 1.096183844 1.086361958 1.207054387 0.927486701 1.008514132 0.799746303 0.88004757 1 11.84820345 -3.957884465 1.716388219 1.022704737 0.535591695 0.32729572 0.100395259 2.371964417 3.484624662 0.01434508 2.433947437 0.000110183 3.957884465 -0.487113042 SQLDIIIHSLKK ddPTM_HeLa_Curcumin_4h_R1 1 SQLDIIIHSLKK 12 1 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 0 30.828 0.01943 623530 779.19 695.48 666.96 508 540.9 2027.4 1182.4 1010 978.6 752.41 FALSE FALSE TRUE 717.5162893 755.5941922 691.6781243 505.8980306 534.4501208 1606.894386 1215.574962 1317.944351 871.2500283 778.5561915 0.921598591 0.970506947 0.888411308 0.649790004 0.686463131 2.063941439 1.561319498 1.692805689 1.119058634 1 9.604657358 -5.264858739 24.99993694 0.916980708 1.75155195 0.838577625 0.176970753 81.57646938 596431.8448 0.024330413 0.056536363 5.43E-06 5.264858739 0.834571242 SQLPTLEQDGGTQNPVS(ph)SPGMSQELR ddPTM_HeLa_Curcumin_4h_R1 1 SQLPTLEQDGGTQNPVSSPGMSQELR 26 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 0 SQLPTLEQDGGTQNPVS(0.458)S(0.458)PGMS(0.084)QELR 99.836 2.07E-06 36264000 3886.9 3618 4297.5 3970.6 3905.2 5068.1 3973.9 4128.3 5011.2 4187.8 TRUE FALSE FALSE 3579.247764 3930.723799 4456.76913 3954.170709 3858.633041 4016.918931 4085.396939 5386.999666 4461.483897 4333.325738 0.825981701 0.907091697 1.028486987 0.912502532 0.890455339 0.926982916 0.942785561 1.243155948 1.029575012 1 12.08125897 -4.259035203 4.320681538 0.921779118 1.267663116 0.66821708 0.062940956 0.101880015 4.451330922 0.009788914 0.108115979 5.51E-05 4.259035203 0.345883998 SQLPTLEQDGGTQNPVSS(ph)PGMSQELR ddPTM_HeLa_Curcumin_4h_R1 1 SQLPTLEQDGGTQNPVSSPGMSQELR 26 0 P46937-6;P46937-7;P46937;P46937-9;P46937-5;P46937-3;P46937-2;P46937-8;H0YCI3;P46937-4 P46937-6 YAP1 Transcriptional coactivator YAP1 1 0 SQLPTLEQDGGTQNPVS(0.238)S(0.758)PGMS(0.005)QELR 185.79 2.20E-15 22631000 2194.3 1956.4 1857.7 2482 1699.4 2995.4 2108.5 2362.4 2162.9 1742.1 TRUE FALSE FALSE 2020.61884 2125.502498 1926.547996 2471.730142 1679.135765 2374.120275 2167.658835 3082.684885 1925.635281 1802.637845 1.120923343 1.179106776 1.068738239 1.371173998 0.931488135 1.317025647 1.202492692 1.710096619 1.068231917 1 10.81589387 -1 0.704768911 1.079425395 78.46721669 0.644929494 0.127312589 117.9271091 0.573459758 0.019988134 14412.3575 0.1 1 77.3877913 SQLQALHIGLDS(ph)SSIGSGPGDAEADDGFPESR ddPTM_HeLa_Curcumin_4h_R1 1 SQLQALHIGLDSSSIGSGPGDAEADDGFPESR 32 0 Q14DU5;E9PF63;O75116 Q14DU5 ROCK2 Rho-associated protein kinase 2 1 0 SQLQALHIGLDS(0.333)S(0.333)S(0.333)IGS(0.002)GPGDAEADDGFPESR 122.06 1.38E-13 14043000 1625.1 1566.1 1627.6 1556.9 1921.3 2664.8 1822.5 975.47 1911.1 1421.6 TRUE FALSE FALSE 1496.47162 1701.466706 1687.920288 1550.45796 1898.389752 2112.090442 1873.634445 1272.886312 1701.457111 1471.000494 1.017315512 1.156673103 1.14746412 1.054015934 1.290543246 1.435818988 1.273714355 0.865320112 1.15666658 1 10.52258202 -6.917386436 0.948864402 1.002486714 1.213817884 0.068779114 0.151402085 0.498639431 0.890505741 0.029718846 0.042673111 1.21E-07 6.917386436 0.21133117 SQLQALHIGLDSS(ph)SIGS(ph)GPGDAEADDGFPESR ddPTM_HeLa_Curcumin_4h_R1 1 SQLQALHIGLDSSSIGSGPGDAEADDGFPESR 32 0 Q14DU5;E9PF63;O75116 Q14DU5 ROCK2 Rho-associated protein kinase 2 2 0 SQLQALHIGLDS(0.298)S(0.451)S(0.451)IGS(0.8)GPGDAEADDGFPESR 69.756 0.00010944 4082100 1223.2 836.48 1078.5 1024.5 1249.4 1662.1 848.89 400.34 1466.4 1038.2 TRUE FALSE FALSE 1126.382429 908.7816039 1118.470159 1020.26089 1234.501721 1317.361724 872.7075687 522.4018231 1305.539589 1074.277373 1.048502424 0.845946891 1.041137221 0.94971831 1.149146163 1.226277084 0.812367077 0.486282069 1.215272351 1 10.06915082 -4.424153742 3.473838495 1.026851495 0.492268904 0.695437268 0.116303333 0.095634055 1.934592703 0.013692674 0.101955295 3.77E-05 4.424153742 -0.53458259 SQLS(ph)SEEEGAVMGK ddPTM_HeLa_Curcumin_4h_R1 1 SQLSSEEEGAVMGK 14 0 Q5TB80-2;Q5TB80 Q5TB80-2 CEP162 Centrosomal protein of 162 kDa 1 0 S(0.036)QLS(0.782)S(0.183)EEEGAVMGK 91.592 0.0089854 3854200 1036.5 844.58 949.87 1408 1059.7 280.28 418.61 461.23 1175.3 700.69 TRUE FALSE FALSE 954.4599313 917.5817318 985.0730178 1402.174069 1047.06377 222.1467686 430.35507 601.8569038 1046.37253 725.0389253 1.316425778 1.265562027 1.358648458 1.933929366 1.444148353 0.306392886 0.593561332 0.830102885 1.44319497 1 9.501914641 -5.265715047 24.99780468 1.255012859 0.578373256 0.62862507 0.273740585 224.8902562 1314830.731 0.044666394 0.10325012 5.42E-06 5.265715047 -0.676639603 SQMTQEAS(ph)DEAEDMKEAMNR ddPTM_HeLa_Curcumin_4h_R1 1 SQMTQEASDEAEDMKEAMNR 20 1 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3 RAI14 Ankycorbin 1 0 SQMT(0.001)QEAS(0.998)DEAEDMKEAMNR 102.29 0.00036736 0 800.32 864.71 694.24 722.97 735.1 641.2 665.84 636.6 1132 956.88 TRUE FALSE FALSE 736.9738275 939.4516793 719.9691451 719.9785417 726.3344126 508.2078922 684.5216784 830.6964095 1007.822432 990.1315088 0.744319134 0.948815052 0.727144969 0.727154459 0.733573678 0.513273124 0.691344203 0.838975835 1.017867246 1 9.951476346 -12.49530175 0.172104839 1.760239975 0.651546316 0.567144897 0.098236035 24.08205148 0.370567367 6.408708896 0.169249288 3.20E-13 12.49530175 -1.108693659 SQNSQESTADES(ph)EDDMSSQASK ddPTM_HeLa_Curcumin_4h_R1 2 SQNSQESTADESEDDMSSQASK 22 0 Q9BXW9;Q9BXW9-1 Q9BXW9 FANCD2 Fanconi anemia group D2 protein 1 0 SQNSQESTADES(1)EDDMSSQASK;SQNSQEST(0.001)ADES(0.801)EDDMS(0.164)S(0.035)QASK ; 157.66 6.42E-07 14486100 5727.7 4730.9 5101.2 7009.3 5458.2 6367.2 4729 3515.4 6007.6 5771.8 TRUE FALSE FALSE 5274.346501 5139.817916 5290.254959 6980.297374 5393.11453 5046.570947 4861.683013 4587.229277 5348.58131 5972.36962 0.883124595 0.860599434 0.885788271 1.168765133 0.903010844 0.844986374 0.814029158 0.768075248 0.895554303 1 12.54408774 -5.177253123 2.749645836 0.947885687 0.797439796 0.354544736 0.085049546 0.246426692 3.606431185 0.01294161 0.038163152 6.65E-06 5.177253123 -0.15044589 SQPAPVS(ph)PQQK ddPTM_HeLa_Curcumin_4h_R1 3 SQPAPVSPQQK 11 0 Q13118-2;Q13118 Q13118-2 KLF10 Krueppel-like factor 10 1 0 SQPAPVS(1)PQQK;SQPAPVS(1)PQQK;SQPAPVS(1)PQQK ;; 153.81 0.00046464 18370900 8068 6085.6 6522.7 7448.9 7442.7 8716.8 7389.3 2806.85 7646.2 5893.9 TRUE FALSE FALSE 7429.409287 6611.612147 6764.437 7418.078425 7353.950663 6908.837421 7596.623871 3662.645644 6807.43099 6098.712586 1.21819305 1.084099645 1.109158188 1.21633514 1.205820173 1.132835385 1.245611064 0.600560461 1.116207871 1 12.57428901 -4.253511046 24.94785312 1.127621704 0.600560199 0.829057506 0.074019986 383.7247631 1207426.799 0.013289713 0.195074762 5.58E-05 4.253511046 -0.527061505 SQPDPVDT(ph)PTSSKPQSK ddPTM_HeLa_Curcumin_4h_R1 2 SQPDPVDTPTSSKPQSK 17 1 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 S(0.023)QPDPVDT(0.948)PT(0.025)S(0.004)S(0.001)KPQSK;S(0.003)QPDPVDT(0.912)PT(0.032)S(0.045)S(0.009)KPQSK ; 80.488 0.0075106 13387200 6656.4 4603.4 5674.8 7337.9 6661 13004.5 12032.9 3370.4 9218.7 6258.6 TRUE FALSE FALSE 6129.538916 5001.297384 5885.11308 7307.537714 6581.571925 10307.22011 12370.51079 4398.019445 8207.431674 6476.085884 0.946488207 0.772271627 0.908745373 1.128388018 1.016288549 1.591581751 1.910183251 0.679116912 1.267344476 1 12.6609064 -5.337001506 5.973613884 0.966229436 1.443964245 0.23255265 0.313874751 0.174492321 10.80685111 0.038980542 0.088475673 4.60E-06 5.337001506 0.47773481 SQPERDWVLNEFR ddPTM_HeLa_Curcumin_4h_R1 1 SQPERDWVLNEFR 13 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2;A0A0U1RQJ0 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 0 180.61 0.00012321 15379000 5724.5 3327.6 3537.5 3622.1 3312.4 5999.5 4550.9 4227.8 5797 4128.5 FALSE FALSE TRUE 5271.399785 3615.222917 3668.602862 3607.11271 3272.901793 4755.136072 4678.586006 5516.836758 5161.083603 4271.965068 1.233951987 0.846266966 0.858762374 0.844368494 0.766134962 1.113102752 1.095183582 1.291404932 1.2081287 1 12.06068413 -4.262677516 1.994340174 1.032647643 1.364763492 0.222034527 0.157952516 1.154791656 4.83873663 0.026334744 0.69782708 5.46E-05 4.262677516 0.332115848 SQPGSSASSSS(ph)GVK ddPTM_HeLa_Curcumin_4h_R1 1 SQPGSSASSSSGVK 14 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 0 SQPGSSASSS(0.036)S(0.964)GVK 142.74 0.00069802 1868900 1023.9 969.69 860.83 989.86 1018.1 2011.2 2021.3 773.52 1176.6 728.42 TRUE FALSE FALSE 942.8572346 1053.505683 892.7331171 985.7642216 1005.959822 1594.054449 2078.012238 1009.362687 1047.529924 753.7325408 1.250917512 1.39771819 1.184416313 1.307843523 1.334637644 2.114880761 2.756962351 1.339152329 1.389789968 1 9.557908869 -5.31863479 3.613273996 1.166998496 2.148347687 0.522530082 0.344238447 0.108184589 2.844601692 0.045623264 0.112136574 4.80E-06 5.31863479 0.981349191 SQPLTS(ph)PESR ddPTM_HeLa_Curcumin_4h_R1 1 SQPLTSPESR 10 0 P46939;P46939-2 P46939 UTRN Utrophin 1 0 SQPLT(0.063)S(0.931)PES(0.005)R 136.27 0.0020321 84341000 4726.3 4236.3 4073.4 4581.3 4461.3 5254.4 3587.2 2473.8 4282.4 3886 TRUE FALSE FALSE 4352.208368 4602.466895 4224.363787 4562.343794 4408.101911 4164.578211 3687.847178 3228.050232 3812.631434 4021.038211 1.082359366 1.144596657 1.050565443 1.134618364 1.096259642 1.035697248 0.917138058 0.80279024 0.948170904 1 11.97335233 -4.557741358 2.173146958 1.059792937 0.797190286 0.698308793 0.055704107 0.161044957 1.2646043 0.007756462 0.064144313 2.77E-05 4.557741358 -0.262602652 SQQK(ac)VVITK(ac)VVMHPSK ddPTM_HeLa_Curcumin_4h_R1 2 SQQKVVITKVVMHPSK 16 2 A6NGA6;Q9Y5S8-3;Q9Y5S8 A6NGA6 NOX1 NADPH oxidase 1 0 2 ; SQQK(1)VVITK(1)VVMHPSK;SQQK(1)VVITK(1)VVMHPSK 57.197 0.016284 27411000 4694.6 3291.1 3115 3792.4 3151.3 5214.5 3898.3 2738 5193.1 3894.3 FALSE TRUE FALSE 4323.017456 3575.568019 3230.44464 3776.708054 3113.722806 4132.95392 4007.675806 3572.803596 4623.429922 4029.626635 1.072808438 0.887319929 0.801673438 0.937235232 0.77270752 1.025641901 0.99455264 0.886633904 1.147359381 1 11.97643046 -7.255075913 24.84852423 1.034381763 0.901888628 0.461076816 0.082309982 354.3287524 1383609.132 0.012810179 0.015486905 5.56E-08 7.255075913 -0.132493135 SQQQPT(ph)PVTPK ddPTM_HeLa_Curcumin_4h_R1 3 SQQQPTPVTPK 11 0 O95251-4;O95251;O95251-2 O95251-4 KAT7 Histone acetyltransferase KAT7 1 0 SQQQPT(0.733)PVT(0.267)PK;S(0.005)QQQPT(0.986)PVT(0.009)PK;SQQQPT(0.999)PVT(0.001)PK ;; 184.98 0.0002666 521330000 32326.5 26177.5 28120.7 30339 29258 34033.9 27779.8 18608.4 31539.2 28795.5 TRUE FALSE FALSE 29767.82341 28440.16646 29162.87788 30213.46526 28909.11746 26974.8855 28559.22642 24282.0155 28079.42867 29796.14148 0.999049606 0.95449159 0.978746792 1.014005967 0.970230239 0.905314721 0.958487408 0.814938253 0.942384727 1 14.8628379 -2.734129506 0.565700628 0.996670694 4.27E-14 0.663692651 0.03201935 5.423361019 0.310666047 0.00466321 5.245339751 0.001844465 2.734129506 -0.996670694 KT(ph)GSYGALAEITASK ddPTM_HeLa_Curcumin_4h_R1 2 KTGSYGALAEITASK 15 1 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 KT(0.615)GS(0.383)YGALAEIT(0.001)ASK;KT(0.598)GS(0.402)YGALAEITASK ; 91.589 0.003583 690613600 9529.7 7802.7 8243.3 9210.3 8995.5 10551 7134.8 2315.74 9797.8 9282.7 TRUE FALSE FALSE 8775.414189 8477.13062 8548.80395 9172.190219 8888.234538 8362.603666 7334.983286 3021.798466 8723.005853 9605.273134 0.913603816 0.882549668 0.890011542 0.954911963 0.925349484 0.870626327 0.763641302 0.31459787 0.908147611 1 13.22961092 -4.179875542 1.52576217 0.943901016 3.93E-17 0.958208398 0.037873295 0.221228691 0.404988414 0.006900268 0.330688243 6.61E-05 4.179875542 -0.943901016 down SQRYS(ph)GAYGASVSDEELK ddPTM_HeLa_Curcumin_4h_R1 1 SQRYSGAYGASVSDEELK 18 1 A0A286YEX5;C9JRZ6;F8WAR4;Q9NX63 A0A286YEX5 CHCHD3 MICOS complex subunit MIC19 1 0 S(0.044)QRYS(0.956)GAYGASVSDEELK 170.98 8.58E-05 34226000 5161.6 3786.8 4485.4 5205.1 4287.8 6127.3 3974.1 3217.8 6028 5341 TRUE FALSE FALSE 4753.053914 4114.114118 4651.63287 5183.562675 4236.670785 4856.428911 4085.60255 4198.892407 5366.743481 5526.599352 0.860032293 0.744420548 0.841680855 0.937929881 0.766596331 0.878737285 0.739261577 0.759760594 0.971075184 1 12.43217631 -13.52287875 0.135156785 1.677165944 0.738638305 0.56207944 0.060793655 38.61961837 0.366577807 6.927157918 0.19557464 3.00E-14 13.52287875 -0.938527639 SQS(ph)AAVTPSSTTSSTR ddPTM_HeLa_Curcumin_4h_R1 1 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 0 S(0.001)QS(0.67)AAVT(0.106)PS(0.218)S(0.003)T(0.001)T(0.001)SSTR 142.4 0.00038529 12231000 2040.4 1958 1563.1 1756.7 1988.8 3031.2 2554.3 2300.3 1979.5 1458.9 TRUE FALSE FALSE 1878.900187 2127.240795 1621.029861 1749.431241 1965.084859 2402.494951 2625.966783 3001.650881 1762.353802 1509.596666 1.244637213 1.409145133 1.073816535 1.15887328 1.301728404 1.591481357 1.739515489 1.988379378 1.167433555 1 10.55994743 -1 0.343746945 1.089930186 11.8823456 0.859330236 0.112522141 14.54659198 0.183082752 0.038504317 102.4936861 0.1 1 10.79241541 STGS(ph)PTQETQAPFIAK ddPTM_HeLa_Curcumin_4h_R1 4 STGSPTQETQAPFIAK 16 0 O15231-3;H0Y704;O15231-2 O15231-3 ZNF185 Zinc finger protein 185 1 0 S(0.01)TGS(0.989)PT(0.001)QETQAPFIAK;ST(0.001)GS(0.945)PT(0.035)QET(0.019)QAPFIAK;S(0.003)T(0.013)GS(0.982)PT(0.002)QETQAPFIAK;S(0.03)T(0.03)GS(0.935)PT(0.005)QETQAPFIAK ;;; 253.36 4.10E-40 178767000 11836.7 9098.2 9656.7 9863.9 11048.6 15680.5 14514.2 17644.5 11784.8 9334.3 TRUE FALSE FALSE 10899.8127 9884.607867 10014.5858 9823.085795 10916.85266 12428.18754 14921.42939 23024.22682 10492.03692 9658.66623 1.128500814 1.023392633 1.036849764 1.017023009 1.130265028 1.28673952 1.54487473 2.383789467 1.086282171 1 13.23760827 -3.726729075 0.967395307 1.053284327 4.842043318 0.988581276 0.043292136 0.421879098 0.147596862 0.008566806 2.139831719 0.000187616 3.726729075 3.788758991 up SQS(ph)CSDTAQER ddPTM_HeLa_Curcumin_4h_R1 1 SQSCSDTAQER 11 0 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 0 S(0.034)QS(0.96)CS(0.006)DTAQER 124.81 0.0035728 5163500 1449.3 1749.5 1188.3 885.65 1051.8 1058.5 568.06 494.21 1126.4 1445.9 TRUE FALSE FALSE 1334.586376 1900.718984 1232.339443 881.985415 1039.257972 838.9551682 583.9982347 644.8923539 1002.836738 1496.144917 0.892016783 1.270411016 0.823676523 0.589505338 0.69462387 0.56074459 0.39033534 0.431036022 0.670280483 1 10.54703421 -5.935609538 1.101532817 0.972466181 0.450714952 0.61685658 0.158763904 0.187620829 0.448650064 0.022188099 0.056496273 1.16E-06 5.935609538 -0.521751229 SQS(ph)DLSSSSSR ddPTM_HeLa_Curcumin_4h_R1 1 SQSDLSSSSSR 11 0 J3KP75 J3KP75 PHACTR2 Phosphatase and actin regulator 1 0 S(0.007)QS(0.977)DLS(0.015)S(0.001)SSSR 136.83 0.001823 63337000 2174.2 1756.1 1939.8 1981.9 2203.5 2392.6 1678.4 796.59 2048.3 1872.1 TRUE FALSE FALSE 2002.109776 1907.889459 2011.690694 1973.699423 2177.224702 1896.34779 1725.491387 1039.466624 1823.606615 1937.155336 1.033530837 0.984892344 1.038476707 1.01886482 1.123928815 0.978934293 0.890734654 0.536594358 0.941383781 1 10.91972393 -4.224884994 1.874073542 1.022205105 0.353361258 0.911322424 0.045026119 0.150540569 0.498641189 0.005321166 0.180684005 5.96E-05 4.224884994 -0.668843846 SQS(ph)ESSDEVTELDLSHGKK ddPTM_HeLa_Curcumin_4h_R1 1 SQSESSDEVTELDLSHGKK 19 1 Q86YS7;Q86YS7-5;Q86YS7-3;Q86YS7-2;Q86YS7-4 Q86YS7;Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 0 S(0.173)QS(0.817)ES(0.005)S(0.005)DEVTELDLSHGKK 108.96 0.00024968 4662800 1645.5 1058.8 1047.4 1157.8 925.25 1079.4 977.85 750.14 773.03 842.07 TRUE FALSE FALSE 1515.256939 1150.317954 1086.217565 1153.00933 914.2169981 855.5202727 1005.285839 978.8542328 688.230543 871.3318698 1.739012414 1.320183496 1.246617509 1.323272303 1.049217904 0.981853531 1.15373473 1.123400012 0.789860404 1 9.767078502 -5.78830993 6.797256308 1.34503317 1.075464827 0 0.247194309 0.233020485 36.9658883 0.040854166 0.075892247 1.63E-06 5.78830993 -0.269568343 SQS(ph)FSHQQPSR ddPTM_HeLa_Curcumin_4h_R1 1 SQSFSHQQPSR 11 0 B3KNS5;Q8WVR3-2;Q8WVR3-3;Q8WVR3 B3KNS5 C7orf43 Uncharacterized protein C7orf43 1 0 S(0.388)QS(0.612)FSHQQPSR 91.969 0.0075557 13070000 2288.9 1881.7 1977.8 2241.8 2277.1 2665.5 1913.9 1307.6 2298.9 2060.1 TRUE FALSE FALSE 2107.73115 2044.345763 2051.099008 2232.524026 2249.94707 2112.645254 1967.598883 1706.281221 2046.716422 2131.688322 0.98876141 0.959026581 0.962194607 1.047303212 1.055476566 0.991066673 0.923023719 0.800436538 0.960138685 1 11.0577808 -4.375266138 2.179457531 0.997684537 0.774084156 0.780043517 0.03187758 0.166820107 1.064596985 0.004479562 0.065388821 4.21E-05 4.375266138 -0.223600381 SQS(ph)FTHSPSGDPK ddPTM_HeLa_Curcumin_4h_R1 1 SQSFTHSPSGDPK 13 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 0 S(0.195)QS(0.598)FT(0.195)HS(0.012)PSGDPK 97.823 0.0038548 24407000 6325 5660.9 5316.6 5660.7 7123.4 10613 7371.8 2748.4 8596.4 6353.9 TRUE FALSE FALSE 5824.369576 6150.202972 5513.637873 5637.277523 7038.458107 8411.744167 7578.632868 3586.374508 7653.396427 6574.697552 0.885876427 0.935435117 0.838614678 0.857420053 1.070537169 1.279411578 1.152696806 0.545481291 1.164068212 1 12.68270881 -5.747343727 24.79937429 0.929463227 1.041177794 0.012515447 0.197778395 458.1067788 805970.844 0.025965634 0.05172588 1.79E-06 5.747343727 0.111714567 SQS(ph)GEDESMNQPGPIK ddPTM_HeLa_Curcumin_4h_R1 3 SQSGEDESMNQPGPIK 16 0 A0A0C4DG33;O43933-2;O43933 A0A0C4DG33 PEX1 Peroxisome biogenesis factor 1 1 0 S(0.01)QS(0.989)GEDES(0.001)MNQPGPIK;S(0.001)QS(0.937)GEDES(0.062)MNQPGPIK;SQS(0.999)GEDES(0.001)MNQPGPIK ;; 211.26 4.74E-11 35839100 9938.4 8592.5 9492.7 10085.7 10171.1 11071.5 6027.5 4869.5 10267.1 8246.4 TRUE FALSE FALSE 9151.765153 9335.197413 9844.507813 10043.96805 10049.81628 8775.146098 6196.615428 6354.188134 9140.824817 8532.961786 1.072519177 1.094016081 1.153703492 1.177078756 1.177764125 1.02838221 0.72619749 0.744663845 1.071237051 1 13.05883087 -4.791475466 5.171313771 1.068949732 0.732030321 0.846846044 0.060715147 0.060855209 4.119113176 0.010868371 0.036281219 1.62E-05 4.791475466 -0.336919411 SQS(ph)IEQESQEK ddPTM_HeLa_Curcumin_4h_R1 2 SQSIEQESQEK 11 0 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 0 S(0.003)QS(0.997)IEQESQEK;S(0.01)QS(0.948)IEQES(0.042)QEK ; 169.17 0.00024615 255146300 4662.2 3705.3 3972.6 3954 3585 4311.1 3299 2303.37 4437.6 3601.3 TRUE FALSE FALSE 4293.18195 4025.569622 4119.828051 3937.639396 3542.251216 3416.929264 3391.561061 3005.65691 3950.806382 3726.444907 1.15208518 1.0802708 1.105565265 1.056674523 0.950571203 0.91694077 0.910133155 0.806574895 1.060207914 1 11.86358422 -5.421251332 1.268101369 1.077719743 0.855435841 0.814491037 0.043549067 0.214197218 0.643916316 0.009679596 0.035189378 3.79E-06 5.421251332 -0.222283901 SQS(ph)LNIR ddPTM_HeLa_Curcumin_4h_R1 1 SQSLNIR 7 0 O00443;A0A0C4DGF9;O00443-2 O00443 PIK3C2A Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1 0 S(0.001)QS(0.999)LNIR 93.096 0.014351 6240800 6269.2 4798 4889.4 5647 5155.9 5374.4 4724.9 2859 5197.4 5170.7 TRUE FALSE FALSE 5772.986205 5212.717741 5070.605465 5623.63421 5094.41926 4259.688858 4857.467978 3730.695939 4627.258223 5350.38144 1.078985913 0.974270302 0.947709153 1.051071643 0.952160013 0.796146762 0.907873211 0.69727663 0.864846418 1 12.38542603 -4.296869346 0.539382165 1.034688995 0.532009931 0.498560748 0.077971839 1.389961312 0.277349743 0.011686705 0.434594482 5.05E-05 4.296869346 -0.502679065 GQTPLTEGS(ph)EDLDGHSDPEESFAR ddPTM_HeLa_Curcumin_4h_R1 1 GQTPLTEGSEDLDGHSDPEESFAR 24 0 K7EQI9;Q86VR2-2;Q86VR2 K7EQI9 FAM134C Protein FAM134C 1 0 GQT(0.002)PLT(0.035)EGS(0.75)EDLDGHS(0.211)DPEES(0.001)FAR 87.652 5.06E-05 18882000 1075.2 781.25 1317.9 1229.4 1502.2 1920.1 2013.3 2016 1440.3 1117.7 TRUE FALSE FALSE 990.0967855 848.7777688 1366.742533 1224.313069 1484.287246 1521.849616 2069.787779 2630.669119 1282.302693 1156.539992 0.856085213 0.733894007 1.181751209 1.058599856 1.283386011 1.315864239 1.78963788 2.274602814 1.108740469 1 10.17559944 -3.705196724 0.58413443 0.922158222 4.304592132 0.917756493 0.124698797 1.01763973 0.149791761 0.021181374 2.691758265 0.000197153 3.705196724 3.382433911 up T(ph)GSYGALAEITASK ddPTM_HeLa_Curcumin_4h_R1 2 TGSYGALAEITASK 14 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;F8VZN8;H0YIS4;H0YHI8;A0A3B3ISH4 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 T(0.679)GS(0.321)YGALAEITASK;T(0.646)GS(0.353)YGALAEITASK ; 184 0.00021334 622420000 7229.8 5565.5 5587.2 6269.9 6499.8 7641.2 5152.5 1593.04 6727.5 6219 TRUE FALSE FALSE 6657.553701 6046.557021 5794.266547 6243.956815 6422.29413 6056.328986 5297.065283 2078.750563 5989.510081 6435.109787 1.034567229 0.93961987 0.90041456 0.970295305 0.998008479 0.941138409 0.823150724 0.323032649 0.930754918 1 12.65174905 -4.179747303 1.710744002 0.996431527 3.52E-15 0.947283428 0.044976472 0.180557922 0.435264835 0.006866054 0.31214204 6.61E-05 4.179747303 -0.996431527 down SQS(ph)LPTTLLSPVR ddPTM_HeLa_Curcumin_4h_R1 1 SQSLPTTLLSPVR 13 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 0 S(0.124)QS(0.825)LPT(0.025)T(0.025)LLSPVR 116.87 0.0027951 92675000 1463.8 765.57 1005.5 950.76 768.17 1399.6 490.86 248.7 1055.4 838.48 TRUE FALSE FALSE 1347.938685 831.7424595 1042.764715 946.826007 759.0100745 1109.307183 504.6322105 324.5274851 939.6252605 867.6171176 1.553610064 0.95865151 1.201871993 1.091294752 0.874821461 1.278567655 0.581630077 0.374044586 1.0829953 1 9.760914707 -4.384685699 0.887058356 1.225643065 2.60E-27 0.576194277 0.20835082 1.077980215 0.707723435 0.039796461 1.223116986 4.12E-05 4.384685699 -1.225643065 HGGPGPGGPEPELS(ph)PITEGSEAR ddPTM_HeLa_Curcumin_4h_R1 4 HGGPGPGGPEPELSPITEGSEAR 23 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 0 HGGPGPGGPEPELS(0.953)PIT(0.039)EGS(0.008)EAR;HGGPGPGGPEPELS(0.974)PIT(0.023)EGS(0.004)EAR;HGGPGPGGPEPELS(0.9)PIT(0.099)EGS(0.002)EAR;HGGPGPGGPEPELS(0.997)PIT(0.003)EGSEAR ;;; 198.83 2.72E-14 112639400 5092.89 4010.67 4563.96 4616.98 5236.88 8219.18 7525.42 12230.2 5972.58 5322.1 TRUE FALSE FALSE 4689.782383 4357.334444 4733.104372 4597.87616 5174.433626 6514.429419 7736.563032 15959.13168 5317.402917 5507.042579 0.851597262 0.791229481 0.859463915 0.834908409 0.939602981 1.182927011 1.404848959 2.897949571 0.965564155 1 12.42706205 -3.699747803 1.168391655 0.905559672 7.405574824 0.981807682 0.081133837 0.502426983 0.224629249 0.013994107 5.490582134 0.000199642 3.699747803 6.500015152 up RFS(ph)LDER ddPTM_HeLa_Curcumin_4h_R1 1 RFSLDER 7 1 Q7LBC6;Q7LBC6-2 Q7LBC6 KDM3B Lysine-specific demethylase 3B 1 0 RFS(1)LDER 80.24 0.015674 28959000 1739.7 1434.6 1498 1789.9 1678 2687.1 2806.2 3604.6 2132.4 1443.2 TRUE FALSE FALSE 1602.000909 1558.600432 1553.517198 1782.493868 1657.990946 2129.76517 2884.934419 4703.625946 1898.481055 1493.351093 1.072755708 1.043693234 1.040289323 1.193620092 1.110248591 1.426165073 1.931852753 3.14971206 1.271289159 1 10.54433767 -3.698145334 0.889348813 1.038560384 7.104572429 0.981281295 0.086593515 0.242703477 0.071273376 0.007525495 1.819712915 0.00020038 3.698145334 6.066012044 up YYGGAGGS(ph)PGKK ddPTM_HeLa_Curcumin_4h_R1 1 YYGGAGGSPGKK 12 1 A0A1B0GTT1;A0A1B0GVM0;Q9BUH8 A0A1B0GTT1 BEGAIN Brain-enriched guanylate kinase-associated protein 1 0 Y(0.038)YGGAGGS(0.962)PGKK 97.779 0.016605 25602000 6496.3 4645.5 5146.6 4909.6 5042.5 5277.8 3837.5 1561.4 6271.1 5240.1 TRUE FALSE FALSE 5982.111 5047.03632 5337.337523 4889.285376 4982.371481 4183.124787 3945.169922 2037.463672 5583.17602 5422.193085 1.103264105 0.930810881 0.984350325 0.901717312 0.918884924 0.771482078 0.727596723 0.375763762 1.029689635 1 12.40466077 -4.179505467 0.590022115 1.039746265 2.37E-19 0.914778638 0.057728278 0.78542844 0.173138513 0.011793836 0.566686766 6.61E-05 4.179505467 -1.039746265 down SQS(ph)PHYFR ddPTM_HeLa_Curcumin_4h_R1 2 SQSPHYFR 8 0 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 0 S(0.064)QS(0.936)PHYFR;S(0.226)QS(0.774)PHYFR ; 101.3 0.006754 99715000 6886.8 5649.9 5501.4 5224 8025.1 11128.7 7374.9 6274.1 8584.5 5965.4 TRUE FALSE FALSE 6341.702513 6138.252181 5705.286724 5202.384472 7929.405924 8820.482174 7581.819845 8187.044208 7642.801827 6172.697206 1.027379491 0.994419777 0.924277756 0.842805713 1.284593373 1.428951053 1.22828313 1.326331737 1.238162439 1 12.59168531 -5.668994925 7.059211234 0.993934107 1.323033103 0.682157573 0.104532572 0.065772753 4.296436342 0.010474118 0.021013577 2.14E-06 5.668994925 0.329098996 ESGGSGFRS(ph)PHLWK ddPTM_HeLa_Curcumin_4h_R1 1 ESGGSGFRSPHLWK 14 1 P00519;P00519-2 P00519 ABL1 Tyrosine-protein kinase ABL1 1 0 ES(0.003)GGS(0.001)GFRS(0.996)PHLWK 62.469 0.019898 35336000 1952.7 2036.3 1763.7 1568.6 1987.7 2189.7 1547.5 597.23 2116.8 1700.1 TRUE FALSE FALSE 1798.141735 2212.308698 1829.064274 1562.109549 1963.997976 1735.531537 1590.918685 779.3226777 1884.592336 1759.178348 1.022148628 1.257580677 1.039726458 0.887976793 1.116429143 0.986558036 0.904353266 0.443003791 1.07129123 1 10.78068604 -4.178506821 1.958222965 1.028703009 0.178651754 0.795958779 0.091668851 0.331782441 1.113530051 0.012783614 0.543763189 6.63E-05 4.178506821 -0.850051255 down SQS(ph)PVHLR ddPTM_HeLa_Curcumin_4h_R1 4 SQSPVHLR 8 0 Q96T58;A0A669KB49 Q96T58 SPEN Msx2-interacting protein 1 0 S(0.006)QS(0.994)PVHLR;S(0.003)QS(0.997)PVHLR;S(0.003)QS(0.997)PVHLR;SQS(1)PVHLR ;;; 105.46 0.0059636 258765800 14806.7 11533.4 11460.3 12747.2 12827.3 16400.2 12101.2 9061.7 14378.2 11603.6 TRUE FALSE FALSE 13634.73407 12530.2957 11885.0288 12694.45546 12674.34283 12998.61365 12440.7271 11824.57062 12800.94743 12006.82424 1.135582049 1.043597829 0.989856149 1.057270034 1.055594933 1.082602143 1.036138021 0.98482083 1.06613932 1 13.55156699 -7.020615526 24.61058287 1.065370385 1.036829388 0.110796531 0.041207427 1615.605509 1928690.114 0.009450808 0.011653622 9.54E-08 7.020615526 -0.028540998 LLPSVWSES(ph)EDGAGSPPPYR ddPTM_HeLa_Curcumin_4h_R1 1 LLPSVWSESEDGAGSPPPYR 20 0 K7EN65;K7EMA9;K7EPZ6;A0A0A0MS90;Q9UIS9-4;Q9UIS9-11;Q9UIS9-8;Q9UIS9-7;Q9UIS9-6;Q9UIS9-5;Q9UIS9-10;Q9UIS9-2;Q9UIS9;Q9UIS9-9;Q9UIS9-12 K7EN65 MBD1 Methyl-CpG-binding domain protein 1 1 0 LLPSVWS(0.006)ES(0.894)EDGAGS(0.099)PPPYR 138.66 0.00012227 2513800 552.25 348.29 658.37 573.87 691.68 974.69 1020.1 1059.6 862.92 504.97 TRUE FALSE FALSE 508.5388298 378.3946356 682.7697714 571.495478 683.4321678 772.528307 1048.721261 1382.667162 768.2598349 522.5176699 0.973247144 0.724175769 1.306692215 1.093734262 1.307959916 1.478473077 2.007054155 2.646163454 1.470304028 1 9.029336015 -3.681254695 0.612698984 0.974856448 5.303786905 0.857515615 0.201244305 0.845210653 0.131988169 0.021089532 3.032040962 0.000208327 3.681254695 4.328930457 up RDSFDDRGPS(ph)LNPVLDYDHGSR ddPTM_HeLa_Curcumin_4h_R1 1 RDSFDDRGPSLNPVLDYDHGSR 22 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 0 RDS(0.015)FDDRGPS(0.985)LNPVLDYDHGSR 102.24 1.95E-05 53207000 2013.1 1664.8 1856.3 1862.5 2463.4 5854.9 6545.5 11199 2521.1 2093.9 TRUE FALSE FALSE 1853.761011 1808.697894 1925.096111 1854.793468 2434.025564 4640.527742 6729.149114 14613.52355 2244.541637 2166.662869 0.855583505 0.834785106 0.888507455 0.856060024 1.123398383 2.141785789 3.105766573 6.744714997 1.03594411 1 11.08125897 -3.666020977 0.913052266 0.901769212 18.55474782 0.992703853 0.151515837 0.289966446 0.084902956 0.023347431 6.610771396 0.000215764 3.666020977 17.65297861 up SQS(ph)SDTEQQS(ph)PTSGGGK ddPTM_HeLa_Curcumin_4h_R1 1 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 0 S(0.032)QS(0.611)S(0.288)DT(0.069)EQQS(0.91)PT(0.084)S(0.007)GGGK 216.9 3.80E-15 66577000 6417.4 5460.3 5471.1 6211.3 6055.6 6733.8 5661.4 5286.7 7015.7 5750.3 TRUE FALSE FALSE 5909.456018 5932.264001 5673.863779 6185.599286 5983.390925 5337.133974 5820.243647 6898.590493 6246.095262 5950.122497 0.993165438 0.996998634 0.953570919 1.039575116 1.005591217 0.89697884 0.978172071 1.159403104 1.049742298 1 12.53870365 -4.259057276 24.81951451 0.989705882 1.15940317 0.608207894 0.040683961 89.92870418 936912.8974 0.004884451 0.044393852 5.51E-05 4.259057276 0.169697288 SQS(ph)SDTEQQSPTSGGGK ddPTM_HeLa_Curcumin_4h_R1 4 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 SQS(0.979)S(0.021)DTEQQSPTSGGGK;SQS(0.499)S(0.499)DT(0.003)EQQSPTSGGGK;SQS(0.5)S(0.5)DTEQQSPTSGGGK;SQS(0.475)S(0.475)DT(0.049)EQQSPTSGGGK ;;; 368.58 2.56E-196 596511200 8063.2 7016.4 7546.5 7720.4 6800.87 9705.7 8821.9 13299.6 8530.6 8454.5 TRUE FALSE FALSE 7424.989212 7622.866352 7826.179929 7688.45503 6719.774067 7692.628414 9069.418771 17354.58682 7594.814523 8748.293246 0.848735748 0.87135469 0.894595061 0.878852002 0.768124008 0.879329053 1.03670722 1.9837683 0.868148141 1 13.09478587 -4.257953837 3.35857456 0.903664142 2.130998784 0.969159869 0.058771289 0.049720162 0.915106416 0.010711259 0.157119045 5.52E-05 4.257953837 1.227334642 SQS(ph)SSQFR ddPTM_HeLa_Curcumin_4h_R1 2 SQSSSQFR 8 0 Q16537-2;Q16537 Q16537-2 PPP2R5E Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform 1 0 SQS(0.477)S(0.477)S(0.046)QFR;S(0.171)QS(0.585)S(0.122)S(0.122)QFR ; 95.483 0.017697 187887000 4125.2 3917.8 3937.1 3422.2 3754.4 5091.5 3000.8 2236.32 4045.7 4186.3 TRUE FALSE FALSE 3798.686067 4256.437175 4083.012389 3408.039843 3709.631232 4035.465507 3084.994372 2918.163673 3601.896832 4331.773613 0.876935502 0.982608408 0.942572894 0.786753914 0.856376986 0.931596585 0.712178116 0.673664862 0.83150625 1 12.08074213 -2.630312278 0.305337161 0.961037604 5.33E-26 0.518314255 0.072666155 9.313497599 0.287720926 0.025964086 4.084334337 0.002342544 2.630312278 -0.961037604 SQS(ph)TTFNPDDMSEPEFKR ddPTM_HeLa_Curcumin_4h_R1 2 SQSTTFNPDDMSEPEFKR 18 1 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2;Q86W92-3 PPFIBP1 Liprin-beta-1 1 0 S(0.034)QS(0.387)T(0.387)T(0.15)FNPDDMS(0.042)EPEFKR;S(0.004)QS(0.422)T(0.422)T(0.149)FNPDDMS(0.003)EPEFKR ; 103.28 0.00071362 42595000 5924.6 4364.2 4470.6 5074.5 4734.5 6069.7 5737.3 3131 5710.3 4993.8 TRUE FALSE FALSE 5455.661658 4741.422002 4636.284369 5053.503064 4678.04418 4810.7758 5898.273197 4085.627487 5083.894376 5167.334178 1.05579811 0.917576034 0.897229443 0.977971017 0.905310943 0.930997616 1.141453793 0.79066446 0.983852447 1 12.33520447 -7.260046511 24.99735401 1.026349108 0.943714335 0.136337146 0.084585316 153.487574 2754591.985 0.013149276 0.015629283 5.49E-08 7.260046511 -0.082634773 SQS(ph)YIPTSGCR ddPTM_HeLa_Curcumin_4h_R1 1 SQSYIPTSGCR 11 0 A0A087WZ32;A0A087X038;A8K727;Q9HB19;E5RHB5 A0A087WZ32 PLEKHA2 Pleckstrin homology domain-containing family A member 2 1 0 S(0.078)QS(0.887)YIPT(0.034)SGCR 164.64 0.00027362 323140000 2943.7 2428.1 3559 3385.7 3131.7 3056 2933 3546.3 2622.1 3278.8 TRUE FALSE FALSE 2710.703039 2637.974145 3690.899671 3371.69087 3094.356523 2422.151152 3015.292086 4627.550545 2334.46219 3392.738056 0.798972097 0.77753546 1.087882297 0.993796401 0.912052882 0.71392224 0.888748862 1.363957508 0.688076165 1 11.72823433 -6.761575263 25 0.892852611 0.972254574 0.133177007 0.178919994 10.40919335 1915188.196 0.028048592 0.038204593 1.73E-07 6.761575263 0.079401963 SQSAAVT(ph)PSSTTSSTR ddPTM_HeLa_Curcumin_4h_R1 1 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 0 SQSAAVT(0.874)PS(0.077)S(0.023)T(0.023)T(0.003)SSTR 173.19 0.00021758 78667000 3969.8 3335.2 4301.8 4381.8 4147.6 6824.3 6070.1 4863.2 5227.9 2728.6 TRUE FALSE FALSE 3655.586141 3623.479827 4461.228492 4363.669273 4098.142579 5408.863254 6240.410669 6345.967293 4654.41245 2823.418647 1.29473755 1.283366117 1.58008041 1.545526831 1.451482437 1.915714221 2.210232151 2.247618255 1.648502412 1 11.46322735 -1 0.20743441 0.976261722 7.959245181 0.67799842 0.217530442 8.380962026 0.097789936 0.095925166 19.39707689 0.1 1 6.982983459 SQSAAVTPS(ph)STTSSTR ddPTM_HeLa_Curcumin_4h_R1 2 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 0 S(0.006)QS(0.298)AAVT(0.225)PS(0.443)S(0.023)T(0.001)T(0.002)SSTR;SQS(0.001)AAVT(0.195)PS(0.412)S(0.128)T(0.128)T(0.128)S(0.006)S(0.001)T(0.001)R ; 137.27 0.00041486 17550000 4029.86 3063.64 2724.54 3482.9 3402.23 5272.6 4387.2 3526.3 3511.98 2587.97 TRUE FALSE FALSE 3710.892329 3328.44739 2825.513849 3468.488683 3361.660629 4179.003326 4510.293024 4601.452637 3126.724581 2677.901765 1.38574625 1.242931101 1.055122292 1.295226258 1.255333812 1.560551392 1.684263808 1.718305241 1.16760242 1 11.38688732 -1 0.258037078 1.11550683 5.564611807 0.758940288 0.115908096 22.27598516 0.280073914 0.078710369 44.01259913 0.1 1 4.449104977 SQSAAVTPSST(ph)TSSTR ddPTM_HeLa_Curcumin_4h_R1 1 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 1 0 SQSAAVT(0.006)PS(0.046)S(0.262)T(0.639)T(0.004)S(0.004)S(0.019)T(0.019)R 102.89 0.0062767 70612000 995.81 953.9 822.29 1002.2 1014.5 1347.3 1159.8 1080.5 1056.7 923.61 TRUE FALSE FALSE 916.9905877 1036.350866 852.7647908 998.0531619 1002.40275 1067.854793 1192.340867 1409.939476 940.7826537 955.7053788 0.959490873 1.084383209 0.892288366 1.0443105 1.048861681 1.117347267 1.247602967 1.475286744 0.984385643 1 9.900422128 -3.828158027 0.731701614 0.982989814 2.133605478 0.913467402 0.0467905 0.821579186 0.201445871 0.007179518 0.90038191 0.00014854 3.828158027 1.150615664 SQSAAVTPSSTTSSTR ddPTM_HeLa_Curcumin_4h_R1 2 SQSAAVTPSSTTSSTR 16 0 Q16186;A0A087WX59 Q16186 ADRM1 Proteasomal ubiquitin receptor ADRM1 0 0 ; ; 284.51 1.29E-93 2391100 940.74 658.84 734.69 860.12 981.72 1034.15 772.24 750.45 857.93 803.22 FALSE FALSE TRUE 866.2794363 715.7871939 761.9182577 856.5610513 970.0136302 819.6556327 793.906976 979.2587504 763.8172254 831.1318352 1.04228884 0.861219801 0.916723708 1.030595888 1.167099597 0.986192079 0.955211848 1.178223128 0.919008505 1 9.698933527 -6.000448586 24.99999946 0.997903673 1.062454955 0.225676646 0.086684159 29.17446419 1626123.027 0.012705579 0.022848844 9.99E-07 6.000448586 0.064551282 VSKS(ph)PSPASTSTVPNMTDAPTAPK ddPTM_HeLa_Curcumin_4h_R1 2 VSKSPSPASTSTVPNMTDAPTAPK 24 1 Q659A1 Q659A1 ICE2 Little elongation complex subunit 2 1 0 VS(0.148)KS(0.486)PS(0.119)PAS(0.204)T(0.03)S(0.012)T(0.001)VPNMTDAPTAPK;VS(0.173)KS(0.801)PS(0.023)PAS(0.001)T(0.001)S(0.001)TVPNMTDAPTAPK ; 105.75 1.75E-06 22103000 12223.4 9365.3 10582.4 10914.3 9849.9 11170.2 7455.8 3944.5 12576.9 10078.6 TRUE FALSE FALSE 11255.90499 10174.7948 10974.59305 10869.13952 9732.446376 8853.374606 7664.989682 5147.159892 11197.24554 10428.8306 1.079306532 0.975641008 1.052332085 1.042220354 0.93322509 0.848932632 0.734980745 0.493551012 1.073681793 1 13.34828977 -4.177489817 0.766629757 1.037164572 0.111770867 0.962413525 0.034252569 0.405470251 0.155287875 0.006305339 0.330255954 6.65E-05 4.177489817 -0.925393706 down SQSES(ph)SDEVTELDLSHGKK ddPTM_HeLa_Curcumin_4h_R1 1 SQSESSDEVTELDLSHGKK 19 1 Q86YS7;Q86YS7-5;Q86YS7-3;Q86YS7-2;Q86YS7-4 Q86YS7;Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 0 S(0.016)QS(0.092)ES(0.44)S(0.44)DEVT(0.013)ELDLSHGKK 61.102 0.0098124 4223900 889.62 743.76 846.15 728.58 816.12 800.75 742.63 517.74 974.41 901.6 TRUE FALSE FALSE 819.2056383 808.0473003 877.5090633 725.565329 806.388302 634.6654237 763.4661991 675.5965426 867.5196609 932.9305329 0.87809929 0.866138766 0.940594216 0.777727069 0.8643605 0.680292263 0.818352677 0.724165968 0.929886664 1 9.86562585 -1.286689421 0.07154305 1.208942227 2.07E-14 0.639278141 0.056712709 75.87005557 0.426203095 1.318082444 9.323471429 0.051678581 1.286689421 -1.208942227 SQSGEDES(ph)MNQPGPIK ddPTM_HeLa_Curcumin_4h_R1 1 SQSGEDESMNQPGPIK 16 0 A0A0C4DG33;O43933-2;O43933 A0A0C4DG33 PEX1 Peroxisome biogenesis factor 1 1 0 SQS(0.062)GEDES(0.938)MNQPGPIK 131.61 0.00053107 7828700 3190.2 2348 2907.1 2851 2893.4 2848.8 2389.4 2036.7 3197.4 2598.3 TRUE FALSE FALSE 2937.692304 2550.950658 3014.839683 2839.203317 2858.898095 2257.926767 2456.440133 2657.680454 2846.65322 2688.590732 1.092651354 0.948805866 1.12134571 1.056019157 1.063344473 0.839817954 0.913653426 0.988503167 1.058790089 1 11.39263444 -5.277353859 24.944143 1.045431555 0.913957705 0.550497973 0.055730123 445.5016071 698272.6434 0.008268803 0.018545313 5.28E-06 5.277353859 -0.13147385 TPAAPAS(ph)PAAVPSEGSGGSTTGWR ddPTM_HeLa_Curcumin_4h_R1 4 TPAAPASPAAVPSEGSGGSTTGWR 24 0 P07199 P07199 CENPB Major centromere autoantigen B 1 0 T(0.001)PAAPAS(0.999)PAAVPSEGSGGSTTGWR;TPAAPAS(0.957)PAAVPS(0.043)EGSGGSTTGWR;T(0.073)PAAPAS(0.924)PAAVPS(0.003)EGSGGSTTGWR;TPAAPAS(0.999)PAAVPS(0.001)EGSGGSTTGWR ;;; 244.33 4.20E-39 182305900 17328.3 12643.7 13844.4 15282.4 13734.2 15657.4 9802 4634.45 15728.3 13543.2 TRUE FALSE FALSE 15956.74677 13736.56509 14357.48564 15219.16548 13570.42864 12409.87874 10077.01774 6047.472471 14002.94484 14013.82519 1.138643201 0.980215245 1.024522958 1.086010798 0.968360062 0.885545422 0.719076883 0.431536171 0.999223599 1 13.77456318 -4.177142311 0.854586961 1.059955677 6.51E-12 0.938199711 0.048776585 0.483118849 0.234511394 0.009335501 0.496492678 6.65E-05 4.177142311 -1.059955677 down SQSIEQES(ph)QEK ddPTM_HeLa_Curcumin_4h_R1 1 SQSIEQESQEK 11 0 A0A0A0MRN0;Q5VTL8 A0A0A0MRN0 PRPF38B Pre-mRNA-splicing factor 38B 1 0 SQS(0.013)IEQES(0.987)QEK 160.56 0.0003408 232590000 4022.5 3378.7 4239.3 4410.6 3566.3 4378.3 2938.5 2124.4 4278 3429.6 TRUE FALSE FALSE 3704.11488 3670.739773 4396.412187 4392.350106 3523.774202 3470.191226 3020.946401 2772.11978 3808.714103 3548.778345 1.043771834 1.034367159 1.238852292 1.23770765 0.992954155 0.977855163 0.851263761 0.781147626 1.073246547 1 11.79310675 -4.789351491 1.806533167 1.053849281 0.780992467 0.599485465 0.086596399 0.267941882 1.562143204 0.014374833 0.087671902 1.62E-05 4.789351491 -0.272856814 TNLQPLESTQS(ph)QDF ddPTM_HeLa_Curcumin_4h_R1 3 TNLQPLESTQSQDF 14 0 Q9Y248 Q9Y248 GINS2 DNA replication complex GINS protein PSF2 1 0 TNLQPLESTQS(1)QDF;TNLQPLESTQS(1)QDF;TNLQPLES(0.001)T(0.037)QS(0.962)QDF ;; 220.99 3.57E-14 25997800 14673.2 11584.4 13352.1 12546 13754.8 21478.1 18246.7 23103.5 15630.5 13428.7 TRUE FALSE FALSE 13511.80074 12585.70392 13846.94057 12494.08798 13590.78299 17023.29995 18758.65329 30147.65079 13915.87326 13895.34633 0.972397551 0.905749567 0.996516405 0.899156285 0.978081631 1.225108 1.349995376 2.169622123 1.001477252 1 13.76231417 -3.665706651 1.004074552 0.973076987 4.764234168 0.976628279 0.055901239 0.520410939 0.175822655 0.008403988 2.838914515 0.00021592 3.665706651 3.791157181 up SPSLSPS(ph)PPSPLEK ddPTM_HeLa_Curcumin_4h_R1 1 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 SPSLS(0.008)PS(0.809)PPS(0.183)PLEK 155.14 0.00039905 40803000 904.2 1030.7 1327.5 1161.2 1341.3 3118.5 3354.8 4340 1305.8 938.34 TRUE FALSE FALSE 832.6316159 1119.789115 1376.698318 1156.395262 1325.305874 2471.687947 3448.926659 5663.246021 1162.557007 970.9472452 0.85754568 1.153295528 1.417891986 1.190997006 1.364961773 2.545645976 3.552125696 5.832702085 1.197343123 1 9.923249101 -3.655818023 0.678200925 0.951581724 14.20281207 0.986100479 0.176679767 0.408458896 0.073614073 0.028264866 5.047238565 0.000220893 3.655818023 13.25123035 up S(ph)TELVLSPDMPR ddPTM_HeLa_Curcumin_4h_R1 3 STELVLSPDMPR 12 0 Q8TDY2-2;Q8TDY2 Q8TDY2-2 RB1CC1 RB1-inducible coiled-coil protein 1 1 0 S(0.989)T(0.011)ELVLSPDMPR;S(0.993)T(0.007)ELVLSPDMPR;S(0.991)T(0.009)ELVLSPDMPR ;; 234.49 2.10E-19 62033000 4143.3 3564.1 3488.01 3568.98 3260.54 3793.4 2459.41 1180.22 4127.71 3762.4 TRUE FALSE FALSE 3815.353433 3872.164923 3617.278719 3554.212506 3221.66019 3006.60608 2528.414425 1540.063645 3674.91054 3893.14312 0.980018796 0.994611501 0.929140956 0.912941651 0.827521643 0.772282443 0.649453243 0.395583619 0.943944373 1 11.92671967 -4.174446838 0.592124823 0.991957333 6.38E-22 0.975876503 0.028288811 0.298765454 0.066084358 0.004250286 0.206595132 6.69E-05 4.174446838 -0.991957333 down SQSLPT(ph)TLLSPVR ddPTM_HeLa_Curcumin_4h_R1 1 SQSLPTTLLSPVR 13 0 E9PHV5;P28290-3;P28290;P28290-2;E7EUL7 E9PHV5 SSFA2 Sperm-specific antigen 2 1 0 SQS(0.039)LPT(0.74)T(0.221)LLSPVR 141.59 0.0026776 89211000 1371 742.73 974.89 895.35 1048.6 1108.3 771.74 208.47 839.45 966.65 TRUE FALSE FALSE 1262.483903 806.9282717 1011.020281 891.6452789 1036.09613 878.4260869 793.3929474 272.0315433 747.3644352 1000.241016 1.262179698 0.806733836 1.010776668 0.89143043 1.035846475 0.878214424 0.793201773 0.271965995 0.747184352 1 9.966131955 -4.279725156 0.927720329 1.079652773 5.44E-45 0.534695447 0.167252275 0.886713834 0.579731963 0.023977453 0.956694424 5.25E-05 4.279725156 -1.079652773 SQSPAAS(ph)DCSSSSSSASLPSSGR ddPTM_HeLa_Curcumin_4h_R1 1 SQSPAASDCSSSSSSASLPSSGR 23 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 0 S(0.002)QS(0.434)PAAS(0.538)DCS(0.01)S(0.005)S(0.005)S(0.005)S(0.001)SASLPSSGR 215.89 5.16E-23 5152900 1716 1266.6 1454.5 1434.8 1151.4 1366.9 1022.1 837.62 1876.2 1451.1 TRUE FALSE FALSE 1580.176789 1376.07926 1508.40505 1428.863178 1137.670307 1083.389532 1050.777375 1093.006482 1670.385554 1501.525617 1.052380839 0.916454068 1.004581628 0.951607593 0.757676255 0.72152584 0.699806492 0.727930626 1.112458912 1 10.55221337 -5.793165018 2.1896507 1.014678044 0.712770899 0.898634519 0.046543941 0.055593141 0.543572655 0.005930379 0.012626176 1.61E-06 5.793165018 -0.301907144 ASVSPMDEPVPDS(ph)ESPIEK ddPTM_HeLa_Curcumin_4h_R1 1 ASVSPMDEPVPDSESPIEK 19 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 ASVSPMDEPVPDS(0.855)ES(0.145)PIEK 187.75 3.36E-08 16455000 4602.6 3935.8 4385.9 4258.8 4576.2 5900.8 5592.5 6676.7 4314.5 3967.9 TRUE FALSE FALSE 4238.299353 4275.993014 4548.445312 4241.178214 4521.631804 4676.907564 5749.410499 8712.395094 3841.210144 4105.78423 1.032275228 1.041455852 1.107814015 1.0329764 1.101283348 1.139102131 1.40031969 2.121980749 0.935560646 1 12.0034421 -3.655052894 1.026407575 1.026242582 4.63179324 0.983083515 0.043185359 0.379483152 0.130188831 0.005512975 2.030146497 0.000221283 3.655052894 3.605550658 up SQSS(ph)DTEQQS(ph)PTSGGGK ddPTM_HeLa_Curcumin_4h_R1 2 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 0 S(0.003)QS(0.119)S(0.604)DT(0.292)EQQS(0.387)PT(0.499)S(0.095)GGGK;S(0.011)QS(0.051)S(0.938)DT(0.001)EQQS(0.992)PT(0.008)S(0.001)GGGK ; 184.66 9.25E-06 496649000 9703.8 8813.9 9331.5 9841.9 9987.2 10896.3 8034.9 7623.6 9826.4 9008.6 TRUE FALSE FALSE 8935.733991 9575.734242 9677.333599 9801.176826 9868.109163 8636.284553 8260.337669 9948.000545 8748.468504 9321.648179 0.958600219 1.027257633 1.038156924 1.051442474 1.058622786 0.926476132 0.886145616 1.067193307 0.938510909 1 13.18636935 -3.92676305 20.37562004 0.98829682 3.518022105 0.157614749 0.05539968 627.0113018 182253.8215 0.007550747 3227.62216 0.000118369 3.92676305 2.529725284 SQSS(ph)DTEQQSPT(ph)SGGGK ddPTM_HeLa_Curcumin_4h_R1 1 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 0 S(0.009)QS(0.097)S(0.864)DT(0.029)EQQS(0.251)PT(0.633)S(0.116)GGGK 130.36 0.00025341 0 1546.2 1603.2 1371.8 1760.6 1310.9 1749.6 1502.3 2195.3 1894.9 1600.8 TRUE FALSE FALSE 1423.816638 1741.773464 1422.640115 1753.315104 1295.268374 1386.713238 1544.450495 2864.636864 1687.034211 1656.427681 0.859570662 1.051524002 0.858860384 1.058491792 0.781964941 0.837171012 0.932398385 1.72940654 1.018477432 1 10.6938595 -4.26154284 8.523537829 0.926865122 1.734137953 0.87054719 0.092087952 0.02074262 23.71618404 0.012248497 0.096111186 5.48E-05 4.26154284 0.807272831 SQSS(ph)DTEQQSPTS(ph)GGGK ddPTM_HeLa_Curcumin_4h_R1 1 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 0 S(0.006)QS(0.082)S(0.89)DT(0.023)EQQS(0.271)PT(0.123)S(0.606)GGGK 195.25 2.07E-26 0 2370 1764.1 1668.9 2025.7 1980.4 2279.5 2021.8 1761.5 2125.5 1651 TRUE FALSE FALSE 2182.411999 1916.580943 1730.750902 2017.31819 1956.785023 1806.706005 2078.526267 2298.573241 1892.337968 1708.372127 1.277480453 1.121875564 1.013099473 1.180842369 1.145409125 1.057559987 1.216670674 1.345475734 1.107684876 1 10.73840655 -9.582505453 1.372051177 1.000115896 1.17610434 0.152286189 0.097496964 0.431622504 1.458618158 0.069690083 0.016292146 2.62E-10 9.582505453 0.175988444 VAAETQSPS(ph)LFGSTK ddPTM_HeLa_Curcumin_4h_R1 1 VAAETQSPSLFGSTK 15 0 Q9UKX7;Q9UKX7-2 Q9UKX7 NUP50 Nuclear pore complex protein Nup50 1 0 VAAETQS(0.083)PS(0.917)LFGSTK 226.39 1.05E-20 32199000 2704.7 2448 2049.8 2086.9 2982.3 4623.2 4824.5 12760 2121.2 1723 TRUE FALSE FALSE 2490.620141 2659.594212 2125.767391 2078.264961 2946.73802 3664.296206 4959.862486 16650.46526 1888.509667 1782.874122 1.396969147 1.491745367 1.192326124 1.165682386 1.65280206 2.055274773 2.781947657 9.339114331 1.059250142 1 10.79998913 -3.651091007 1.274250494 1.240878631 32.14332493 0.986138987 0.282240065 0.458041923 0.209399376 0.044567433 27.15378497 0.00022331 3.651091007 30.9024463 up SQSS(ph)SQFR ddPTM_HeLa_Curcumin_4h_R1 1 SQSSSQFR 8 0 Q16537-2;Q16537 Q16537-2 PPP2R5E Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform 1 0 SQS(0.158)S(0.421)S(0.421)QFR 94.409 0.018325 36509000 2073.5 1512.3 1895.9 1580 1626.9 1966 1441.5 1310.5 1793.9 1888.3 TRUE FALSE FALSE 1909.380287 1643.016473 1966.163722 1573.462379 1607.50028 1558.229439 1481.94461 1710.065417 1597.113658 1953.918284 0.977205803 0.8408829 1.006267118 0.805285662 0.822705992 0.797489563 0.758447588 0.875198022 0.8173902 1 10.93215442 -6.561372697 0.720223474 0.994506233 0.7962272 0.161667623 0.079151239 0.264178084 0.275387682 0.011443212 0.022323091 2.75E-07 6.561372697 -0.198279033 SQSSDTEQQS(ph)PTSGGGK ddPTM_HeLa_Curcumin_4h_R1 9 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 SQS(0.001)S(0.052)DTEQQS(0.764)PT(0.176)S(0.006)GGGK;SQS(0.003)SDT(0.005)EQQS(0.827)PT(0.125)S(0.04)GGGK;SQSSDTEQQS(0.98)PT(0.019)S(0.001)GGGK;SQSSDTEQQS(0.718)PT(0.217)S(0.066)GGGK;SQSS(0.001)DT(0.001)EQQS(0.978)PT(0.021)SGGGK;SQS(0.002)SDTEQQS(0.971)PT(0.024)S(0.002)GGGK;SQSSDTEQQS(0.993)PT(0.007)S(0.001)GGGK;SQSSDT(0.003)EQQS(0.789)PT(0.207)S(0.001)GGGK;S(0.087)QS(0.011)S(0.034)DT(0.27)EQQS(0.596)PTS(0.001)GGGK ;;;;;;;; 303.34 3.64E-95 2652730700 27444.63 23722.06 25009.48 24850.72 24892.65 28992.48 20850.92 18967.42 29392 24640.74 TRUE FALSE FALSE 25272.35858 25772.48916 25936.35333 24747.89431 24595.82141 22979.11284 21435.9407 24750.49904 26167.77114 25497.00388 0.991189345 1.010804614 1.017231415 0.970619702 0.964655358 0.901247572 0.840723906 0.97072186 1.026307689 1 14.63804011 -5.473658427 2.105119855 0.997631355 0.897230372 0.642162575 0.032698804 0.133894266 1.164009731 0.004254988 0.011078584 3.36E-06 5.473658427 -0.100400983 SQSSDTEQQSPTSGGGK ddPTM_HeLa_Curcumin_4h_R1 2 SQSSDTEQQSPTSGGGK 17 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 0 ; ; 370.26 6.25E-260 1452830 1505.62 942.25 1242.61 1149.98 1064.29 1360.29 1127.08 759.82 1613.75 1133.81 FALSE FALSE TRUE 1386.448588 1023.693891 1288.66222 1145.221687 1051.599037 1078.15052 1158.702831 991.4856202 1436.725662 1173.209813 1.181756727 0.872558241 1.098407297 0.976143972 0.89634354 0.918975028 0.987634793 0.84510512 1.224611017 1 10.19624533 -6.281284685 1.053862785 1.077447406 0.913551933 0.401257145 0.095221098 0.421076334 0.925726712 0.01690703 0.03472017 5.23E-07 6.281284685 -0.163895473 SQSSEGVSS(ph)LSS(ph)SPSNSLETQSQSLSR ddPTM_HeLa_Curcumin_4h_R1 1 SQSSEGVSSLSSSPSNSLETQSQSLSR 27 0 O95155-2;O95155;O95155-4 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 2 0 S(0.001)QS(0.001)S(0.001)EGVS(0.224)S(0.759)LS(0.016)S(0.556)S(0.442)PSNSLETQSQSLSR 133.56 7.00E-08 15784000 2521 1468.5 2214.8 2377.2 2071.6 2366.2 1477.4 509.32 1983.9 2298.6 TRUE FALSE FALSE 2321.46019 1595.430596 2296.882436 2367.363776 2046.897523 1875.423447 1518.851868 664.6093234 1766.271133 2378.476179 0.976028354 0.670778463 0.965694951 0.995327932 0.86059198 0.78849789 0.638581913 0.279426521 0.74260619 1 11.21582186 -4.310255379 0.958363772 0.961158948 3.12E-20 0.690670767 0.118865432 0.583072607 0.425609586 0.015640635 0.56827082 4.89E-05 4.310255379 -0.961158948 EDLVGPEVGASPQS(ph)GRK ddPTM_HeLa_Curcumin_4h_R1 1 EDLVGPEVGASPQSGRK 17 1 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 0 EDLVGPEVGAS(0.087)PQS(0.913)GRK 87.793 0.0025347 23897000 2080.3 1733.6 2061.2 1857.6 2169.3 2196.7 1609.9 611.26 1786.3 1654.6 TRUE FALSE FALSE 1915.64206 1883.444659 2137.589885 1849.913743 2143.432514 1741.079658 1655.069461 797.6303601 1590.347359 1712.097227 1.118886258 1.100080433 1.248521317 1.08049573 1.251933874 1.016928029 0.966691281 0.465879126 0.928888462 1 10.74154892 -4.172959418 1.979615751 1.088318415 0.180889383 0.795218891 0.095398743 0.320040339 1.089862462 0.012980815 0.567349704 6.71E-05 4.172959418 -0.907429032 down NSSS(ph)PVS(ph)PASVPGQR ddPTM_HeLa_Curcumin_4h_R1 1 NSSSPVSPASVPGQR 15 0 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 2 0 NS(0.018)S(0.118)S(0.865)PVS(0.997)PAS(0.003)VPGQR 102.03 0.0077968 61925000 5993.3 4986.6 5255.3 5482.9 5464.7 5785.9 4397.7 1346.4 6522.5 5081.8 TRUE FALSE FALSE 5518.923981 5417.619484 5450.066041 5460.213213 5399.537022 4585.839119 4521.087626 1756.911162 5806.998068 5258.392172 1.049545907 1.030280608 1.036451041 1.038380751 1.026841826 0.872099107 0.859785174 0.334115658 1.10432959 1 12.36040603 -4.172515873 1.425431961 1.023868057 2.12E-18 0.946589713 0.04930686 0.197388071 0.303758525 0.005988224 0.304295878 6.72E-05 4.172515873 -1.023868057 down SQSSSLLDMGNMS(ph)ASDLDVADRTK ddPTM_HeLa_Curcumin_4h_R1 1 SQSSSLLDMGNMSASDLDVADRTK 24 1 Q9NV70-2;Q9NV70 Q9NV70-2 EXOC1 Exocyst complex component 1 1 0 S(0.001)QS(0.001)SS(0.001)LLDMGNMS(0.553)AS(0.444)DLDVADRTK 63.625 0.00097612 7759000 1518.5 1027.9 1011.3 1177.3 1084.9 1631.1 1277.7 877.96 1695.7 1492.8 TRUE FALSE FALSE 1398.309123 1116.747096 1048.779668 1172.428645 1071.963276 1292.791474 1313.548823 1145.645962 1509.685952 1544.674689 0.905245054 0.72296588 0.678964752 0.759013307 0.693973484 0.836934458 0.850372465 0.741674587 0.977348799 1 10.59308732 -7.473282934 2.497336905 0.963441667 0.756729117 0.74966928 0.054937541 0.112786256 1.37154546 0.011560868 0.012719533 3.36E-08 7.473282934 -0.20671255 SQSST(ph)SPEGQALENR ddPTM_HeLa_Curcumin_4h_R1 1 SQSSTSPEGQALENR 15 0 O60239-2;O60239 O60239-2 SH3BP5 SH3 domain-binding protein 5 1 0 S(0.002)QS(0.003)S(0.064)T(0.466)S(0.466)PEGQALENR 157.83 0.00099589 12639000 1407.8 948.21 1018.2 1276.7 1347.9 1683.2 1291.7 1484.7 1301.1 1325.5 TRUE FALSE FALSE 1296.371144 1030.169047 1055.935388 1271.417354 1331.827173 1334.085346 1327.941626 1937.378195 1158.372585 1371.561026 0.945179339 0.751092389 0.769878531 0.926985624 0.971030196 0.972676622 0.968197259 1.412535176 0.844565107 1 10.4216031 -4.256414112 4.252314763 0.940132258 1.451164047 0.735306221 0.089262259 0.099625493 4.087488603 0.013430421 0.154689399 5.54E-05 4.256414112 0.511031788 SQSSTSTTGAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 SQSSTSTTGAKK 12 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 0 1 SQSSTSTTGAK(1)K 162.49 3.86E-25 0 114.14 0 173.79 0 0 152.36 0 0 0 0 FALSE TRUE FALSE 105.1056986 0 180.2308103 0 0 120.7588185 0 0 0 0 0 SQST(ph)TFNPDDMSEPEFK ddPTM_HeLa_Curcumin_4h_R1 2 SQSTTFNPDDMSEPEFK 17 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2;Q86W92-3 PPFIBP1 Liprin-beta-1 1 0 S(0.001)QS(0.023)T(0.887)T(0.089)FNPDDMSEPEFK;SQS(0.024)T(0.817)T(0.158)FNPDDMSEPEFK ; 284.57 8.14E-66 61252000 5255.3 4087.3 4939.6 4624 5056 6136.5 6139.8 2753.4 4423.1 3645.7 TRUE FALSE FALSE 4839.33746 4440.587999 5122.665921 4604.867113 4995.710502 4863.720727 6312.066264 3592.898985 3937.896996 3772.387804 1.282831382 1.177129243 1.35793725 1.220677023 1.324283388 1.289294998 1.673228361 0.952420369 1.043873854 1 11.88126228 -9.765438467 0.336764069 0.816953777 1.328103752 0.275422454 0.169272004 3.793587468 0.429463558 0.752550088 0.067247261 1.72E-10 9.765438467 0.511149976 MYS(ph)FDDVLEEGK ddPTM_HeLa_Curcumin_4h_R1 1 MYSFDDVLEEGK 12 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424;E9PJ10 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 MYS(1)FDDVLEEGK 126.34 0.0034011 22472000 3557.9 3912.4 4637.7 3677.1 4636.6 6465.5 8432.4 13124 4329.1 3436 TRUE FALSE FALSE 3276.288461 4250.570423 4809.577242 3661.885135 4581.311573 5124.482419 8668.990449 17125.44718 3854.208561 3555.400744 0.921496252 1.195524985 1.352752499 1.029950039 1.288549984 1.441323436 2.438259727 4.816741745 1.084043358 1 11.79579647 -3.644983895 0.972412825 1.012800827 13.36182842 0.985320458 0.136948537 0.460787286 0.143819389 0.023146242 7.973567207 0.000226473 3.644983895 12.34902759 up SQSTT(ph)FNPDDMSEPEFK ddPTM_HeLa_Curcumin_4h_R1 1 SQSTTFNPDDMSEPEFK 17 0 Q86W92-2;Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-2;Q86W92-3 PPFIBP1 Liprin-beta-1 1 0 SQS(0.001)T(0.037)T(0.957)FNPDDMS(0.006)EPEFK 183.88 0.0001222 24353000 3495.9 2711.2 3186.8 3309.3 3547.3 4265.8 3680.5 2171.8 3452.6 2606.4 TRUE FALSE FALSE 3219.195826 2945.544047 3304.905611 3295.606993 3505.000764 3381.024995 3783.764924 2833.971822 3073.858418 2696.972206 1.193633297 1.092167001 1.2254133 1.221965501 1.299605816 1.253637315 1.402967712 1.050797563 1.139744196 1 11.39712494 -9.288325431 0.271399116 0.879699952 1.273665042 0.243376224 0.099649595 2.847713225 0.286555764 0.371415863 0.065001997 5.15E-10 9.288325431 0.39396509 SQT(ph)DDEEMTGE ddPTM_HeLa_Curcumin_4h_R1 1 SQTDDEEMTGE 11 0 M0QY77;Q9BQD3 M0QY77 KXD1 KxDL motif-containing protein 1 1 0 S(0.02)QT(0.962)DDEEMT(0.018)GE 160.18 0.0092208 6848500 4092.6 2947.8 3550.2 3478.6 3117.1 4273.9 2918.4 1892.3 4112.5 3590.3 TRUE FALSE FALSE 3768.666392 3202.594697 3681.773535 3464.206475 3079.930618 3387.444963 3000.28245 2469.253559 3661.369039 3715.062658 1.014428756 0.862056711 0.991039418 0.932475921 0.829038674 0.911813683 0.80759942 0.664660003 0.985547049 1 11.85917083 -2.941821156 0.343203605 1.009634018 6.66E-18 0.768375146 0.050543522 4.580882463 0.188916613 0.015569541 2.322574751 0.001143349 2.941821156 -1.009634018 SQT(ph)PPGVATPPIPK ddPTM_HeLa_Curcumin_4h_R1 4 SQTPPGVATPPIPK 14 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 0 S(0.001)QT(0.999)PPGVATPPIPK;S(0.011)QT(0.989)PPGVATPPIPK;S(0.004)QT(0.996)PPGVATPPIPK;S(0.013)QT(0.987)PPGVATPPIPK ;;; 168.47 0.0006021 259177000 26935.9 21665.7 21996.6 23177.3 22198.5 25605.4 20763.3 13761.1 25340.3 22269.6 TRUE FALSE FALSE 24803.89509 23538.38657 22811.81335 23081.39847 21933.79739 20294.55141 21345.86232 17956.79604 22560.53249 23043.46694 1.076395976 1.021477655 0.989947103 1.001646086 0.951844505 0.88070738 0.926330329 0.779257569 0.979042457 1 14.49207017 -4.644771561 0.580085929 1.035983615 0.721543922 0.781904016 0.036793625 0.802359639 0.238367349 0.007417899 0.154556363 2.27E-05 4.644771561 -0.314439694 QIESSDYDSSSSK(ac)GK ddPTM_HeLa_Curcumin_4h_R1 1 QIESSDYDSSSSKGK 15 1 Q9UNL4-8;Q9UNL4-3;Q9UNL4-6;Q9UNL4-2;Q9UNL4 Q9UNL4-8 ING4 Inhibitor of growth protein 4 0 1 QIESSDYDSSSSK(1)GK 255.85 1.58E-61 1588700 495.78 414.79 330.43 523.44 585.65 708.07 517.21 750.22 709.02 433.39 FALSE TRUE FALSE 456.5384899 450.6425993 342.6760265 521.274144 578.6665063 561.2083004 531.7215206 978.9586244 631.2422799 448.4502702 1.018035934 1.004888678 0.764133839 1.162390077 1.2903694 1.251439318 1.185686699 2.182981457 1.407608205 1 8.8088042 -1.314726481 0.837657637 1.011887144 199.9999999 0.733522365 0.18725058 86.43413397 0.437029159 0.021559083 32484.99469 0.04844774 1.314726481 198.9881128 up YPDVAS(ph)PTLRR ddPTM_HeLa_Curcumin_4h_R1 2 YPDVASPTLRR 11 1 A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-11;Q8IVL1;A0A0A0MTL4;Q8IVL1-4;Q8IVL1-3;Q8IVL1-2;Q8IVL1-5;E9PNV5 A0A0A0MTE8 NAV2 Neuron navigator 2 1 0 YPDVAS(0.838)PT(0.162)LRR;YPDVAS(0.763)PT(0.237)LRR ; 106.29 0.0037875 58852000 11259.1 8658.4 8715 9689.5 9045 10213.8 8439.4 2184.6 11317.7 8978.5 TRUE FALSE FALSE 10367.93035 9406.793515 9037.985566 9649.407416 8937.144282 8095.342747 8676.186851 2850.674483 10076.17663 9290.502207 1.115970926 1.012517225 0.972819915 1.038631411 0.961965681 0.871356851 0.933877056 0.306837501 1.084567486 1 13.18154087 -4.169279259 1.759024938 1.032668029 1.26E-37 0.901818789 0.068407457 0.279400404 0.705552078 0.010890598 0.515924188 6.77E-05 4.169279259 -1.032668029 down SQTTT(ph)ERDSDT(ph)DVEEEELPVENR ddPTM_HeLa_Curcumin_4h_R1 1 SQTTTERDSDTDVEEEELPVENR 23 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 2 0 S(0.02)QT(0.075)T(0.162)T(0.733)ERDS(0.059)DT(0.951)DVEEEELPVENR 92.798 9.42E-05 24866000 2329.3 1527.2 1646.6 2289 1584 2239.8 1805.9 991.7 2595.3 1851.3 TRUE FALSE FALSE 2144.933447 1659.204363 1707.624444 2279.528725 1565.111835 1775.240232 1856.568694 1294.064765 2310.602083 1915.632537 1.119699841 0.866139163 0.891415452 1.189961373 0.817020908 0.926712299 0.969167446 0.675528704 1.206182312 1 10.90360513 -3.055165235 0.446408851 1.042544171 5.41E-14 0.387655609 0.12527296 9.630994102 0.579082076 0.025669211 6.764913866 0.000880714 3.055165235 -1.042544171 SQTTT(ph)ERDSDTDVEEEELPVENR ddPTM_HeLa_Curcumin_4h_R1 1 SQTTTERDSDTDVEEEELPVENR 23 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 S(0.015)QT(0.195)T(0.117)T(0.553)ERDS(0.117)DT(0.002)DVEEEELPVENR 101 4.24E-05 20924000 926.94 681.26 870.24 797.4 794.81 657.38 525.91 366.45 1183.4 715.53 TRUE FALSE FALSE 853.5717209 740.1450788 902.4918599 794.1005701 785.3324099 521.0319778 540.6656192 478.1789181 1053.583981 740.3946142 1.152860521 0.99966297 1.218933583 1.072536935 1.060694385 0.703721999 0.730239806 0.645843323 1.423003302 1 9.532150591 -5.266209643 5.120987928 1.079556921 0.693673037 0.708019581 0.126163615 0.048000456 4.09556619 0.010617853 0.025877541 5.42E-06 5.266209643 -0.385883884 SQTTTERDS(ph)DT(ph)DVEEEELPVENR ddPTM_HeLa_Curcumin_4h_R1 1 SQTTTERDSDTDVEEEELPVENR 23 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 2 0 S(0.18)QT(0.21)T(0.21)T(0.201)ERDS(0.777)DT(0.423)DVEEEELPVENR 80.56 0.00083055 50273000 653.81 443.15 389.45 726.2 665.42 600.36 579.91 392.25 649.54 470.15 TRUE FALSE FALSE 602.0602486 481.4539114 403.8833596 723.1951768 657.4853011 475.8385685 596.1807139 511.8452193 578.2870871 486.4876775 1.237565259 0.989652839 0.830202651 1.486564224 1.351494255 0.978110219 1.225479578 1.052123708 1.188698324 1 8.926259452 -6.26660773 24.9923484 1.084668054 1.213133329 0.183854435 0.170402375 785.4746959 3798279.22 0.027824459 0.043316454 5.41E-07 6.26660773 0.128465275 SQTTTERDS(ph)DTDVEEEELPVENR ddPTM_HeLa_Curcumin_4h_R1 1 SQTTTERDSDTDVEEEELPVENR 23 1 Q14676;Q14676-3;Q14676-2;Q14676-4 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 S(0.007)QT(0.023)T(0.076)T(0.433)ERDS(0.456)DT(0.005)DVEEEELPVENR 131.64 4.15E-06 30542000 1307.1 794.1 1037 1022.7 1136.7 829.52 618.52 367.79 1584 882.42 TRUE FALSE FALSE 1203.641656 862.7384656 1075.432132 1018.468338 1123.145595 657.4682014 635.8740065 479.9274779 1410.239163 913.0840293 1.318215648 0.944862069 1.17780193 1.115415784 1.230057211 0.720052241 0.696402506 0.525611513 1.54447906 1 9.834603824 -5.16460428 4.235816539 1.141669491 0.631956833 0.683954776 0.167408446 0.088485297 2.774808592 0.019328529 0.05194305 6.85E-06 5.16460428 -0.509712658 SQTVPSPT(ph)INNSGQYSR ddPTM_HeLa_Curcumin_4h_R1 1 SQTVPSPTINNSGQYSR 17 0 Q9P2D1;Q9P2D1-2;Q9P2D1-4;Q9P2D1-3 Q9P2D1 CHD7 Chromodomain-helicase-DNA-binding protein 7 1 0 SQTVPS(0.004)PT(0.531)INNS(0.163)GQY(0.008)S(0.293)R 114.28 0.0026157 3040800 1247.3 900.61 1031.1 1187 1151.4 1384.4 1107.2 697.16 1239.6 1042.7 TRUE FALSE FALSE 1148.574889 978.4547154 1069.313473 1182.088509 1137.670307 1097.259835 1138.265052 909.7208747 1103.618981 1078.933747 1.064546263 0.906871917 0.991083536 1.095608059 1.05443945 1.016985368 1.054990684 0.843166577 1.022879286 1 10.07539056 -4.255903696 24.63713411 1.026445969 0.84316648 0.545422588 0.049176757 299.2230639 1331672.794 0.007055331 0.082138322 5.55E-05 4.255903696 -0.183279489 SQVEEELFSVR ddPTM_HeLa_Curcumin_4h_R1 3 SQVEEELFSVR 11 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ;; ;; 191.33 6.78E-12 8940700 3411.37 2795.91 3057.51 3270.84 3139.15 3655.3 2941.55 2339.62 3448.24 2714.67 FALSE FALSE TRUE 3141.356465 3037.576002 3170.82401 3257.306131 3101.717686 2897.149576 3024.081976 3052.959368 3069.976699 2809.00458 1.118316605 1.081370968 1.128806992 1.159594453 1.104205279 1.031379442 1.076567122 1.086847415 1.092905551 1 11.45584326 -9.307335505 0.939208805 0.99761024 1.099266612 0.03649002 0.042924159 0.382297043 0.581548502 0.027225681 0.006618441 4.93E-10 9.307335505 0.101656371 SQWES(ph)PSPTPSYR ddPTM_HeLa_Curcumin_4h_R1 2 SQWESPSPTPSYR 13 0 Q92620 Q92620 DHX38 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 1 0 S(0.072)QWES(0.782)PS(0.104)PT(0.01)PS(0.032)YR;S(0.088)QWES(0.538)PS(0.33)PT(0.039)PS(0.005)YR ; 132.31 0.0014978 3230500 3673.5 2678.42 3026.7 3081.2 2989.4 3982.8 2337.35 1348.93 3692.6 2444.17 TRUE FALSE FALSE 3382.738599 2909.93069 3138.872165 3068.450811 2953.753357 3156.722385 2402.92975 1760.212547 3287.531018 2529.104726 1.33752413 1.15057738 1.241100115 1.213255734 1.167904724 1.248158035 0.950110814 0.695982467 1.299879355 1 11.30441106 -4.474543608 2.851126175 1.176827133 0.694161677 0.748221111 0.093153533 0.15852114 2.236367075 0.017701701 0.138264063 3.35E-05 4.474543608 -0.482665456 SRADLT(ph)AEMISAPLGDFR ddPTM_HeLa_Curcumin_4h_R1 1 SRADLTAEMISAPLGDFR 18 1 Q9H3Q1;Q9H3Q1-2;J3KRZ9;J3QQS6;J3QR93 Q9H3Q1 CDC42EP4 Cdc42 effector protein 4 1 0 S(0.121)RADLT(0.879)AEMISAPLGDFR 86.136 0.0023707 13143000 719.28 649.8 797.33 777.61 736.03 1465.6 1248.4 411.15 1033.7 691.76 TRUE FALSE FALSE 662.348229 705.9658165 826.8797512 774.3924559 727.253323 1161.618039 1283.426744 536.5077423 920.3056962 715.7986085 0.925327629 0.986263187 1.15518491 1.081858007 1.016002706 1.622828021 1.792999775 0.74952331 1.285704785 1 9.483409929 -5.309225153 10.13860288 0.992123582 1.428736122 0.191320855 0.275252767 0.468930131 98.27563794 0.034231463 0.076720429 4.91E-06 5.309225153 0.43661254 SRAEAALEEESR ddPTM_HeLa_Curcumin_4h_R1 1 SRAEAALEEESR 12 1 J3KT85;A0A2U3TZQ7;B4DGM3;A0A2R8Y855;A0A2R8YES3;A0A2R8Y4T4;A0A2R8YD78;A0A2R8Y7I9;A0A2R8Y7U4;J3QKS7;A0A2R8Y765;J3QR61;Q969G3-5;Q969G3-6;Q969G3-3;Q969G3-2;Q969G3-4;Q969G3 J3KT85 SMARCE1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 0 0 111.31 0.0044749 3437000 2216.9 1816.9 1961.1 1928.6 1841.4 2212.1 1868.3 1942.9 2492.4 1916.2 FALSE FALSE TRUE 2041.430026 1973.94474 2033.780091 1920.619964 1819.442508 1753.285524 1920.71947 2535.281266 2218.989956 1982.787807 1.02957564 0.995540084 1.025717469 0.968646245 0.917618366 0.884252726 0.96869643 1.278644773 1.119126286 1 10.95331458 -4.258414029 24.95567422 0.993425838 1.27864488 0.668876761 0.060900711 115.2002459 950220.5994 0.007475392 0.070582697 5.52E-05 4.258414029 0.285219042 SRDAT(ph)PPVS(ph)PINMEDQER ddPTM_HeLa_Curcumin_4h_R1 2 SRDATPPVSPINMEDQER 18 1 P17275 P17275 JUNB Transcription factor jun-B 2 0 S(0.145)RDAT(0.856)PPVS(1)PINMEDQER;S(0.001)RDAT(0.999)PPVS(1)PINMEDQER ; 111.81 0.00091945 44407000 4309.2 3149.7 3544.7 3597.7 3411.4 4097.8 3687.8 3556.4 4041.7 3178.1 TRUE FALSE FALSE 3968.122273 3421.946033 3676.0697 3582.813671 3370.721283 3247.870088 3791.269743 4640.729988 3598.335622 3288.538738 1.20665213 1.040567348 1.117842906 1.089485013 1.024990596 0.987633215 1.152873676 1.411183008 1.094205028 1 11.68323095 -4.298963392 3.515139518 1.084900311 1.438061615 0.725992777 0.062306619 0.140168089 3.00554607 0.011647457 0.12279481 5.02E-05 4.298963392 0.353161304 SRDAT(ph)PPVSPINMEDQER ddPTM_HeLa_Curcumin_4h_R1 2 SRDATPPVSPINMEDQER 18 1 P17275 P17275 JUNB Transcription factor jun-B 1 0 S(0.013)RDAT(0.987)PPVSPINMEDQER;SRDAT(0.972)PPVS(0.028)PINMEDQER ; 164.69 2.74E-05 6665400 3014.9 2424.6 2450.5 2804.3 2671.3 2869.9 2331 1598.65 2917.1 2131.9 TRUE FALSE FALSE 2776.267484 2634.17162 2541.317686 2792.69655 2639.446492 2274.65039 2396.401586 2086.071026 2597.101428 2205.983366 1.258516962 1.19410312 1.152011264 1.265964464 1.196494286 1.031127625 1.086318974 0.945642228 1.177298736 1 11.1072062 -4.418113551 1.301314861 1.145534691 0.909302552 0.411221762 0.080044741 1.255540716 2.223253926 0.016534365 0.362470822 3.82E-05 4.418113551 -0.236232139 SRDEDNDEDEERLEEEEQNEEEEVDN ddPTM_HeLa_Curcumin_4h_R1 2 SRDEDNDEDEERLEEEEQNEEEEVDN 26 2 Q9NRF9 Q9NRF9 POLE3 DNA polymerase epsilon subunit 3 0 0 ; ; 83.395 0.00018953 10875000 1447.54 1355.44 1572.7 1749.41 1757.04 2206.5 1900.23 1580.16 1613.55 1333.83 FALSE FALSE TRUE 1332.965682 1472.598194 1630.985645 1742.171405 1736.088446 1748.847028 1953.54534 2061.94351 1436.547602 1380.180493 0.965790843 1.06696059 1.181719097 1.262277951 1.257870586 1.267114726 1.415427438 1.493966564 1.040840389 1 10.43064123 -5.772608964 0.52285468 0.972356675 1.501065192 0.907292241 0.05118027 0.257538444 0.111962055 0.01352236 0.064286039 1.69E-06 5.772608964 0.528708518 SRDS(ph)GDENEPIQER ddPTM_HeLa_Curcumin_4h_R1 1 SRDSGDENEPIQER 14 1 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;Q8WX93-4;Q8WX93-7 Q8WX93-3 PALLD Palladin 1 0 S(0.001)RDS(0.999)GDENEPIQER 123.08 0.014644 52971000 1729.3 1669.3 1336.8 2041.8 2050.7 2365.9 1556.7 1528.1 2119.3 1665.7 TRUE FALSE FALSE 1592.42408 1813.586854 1386.342984 2033.351573 2026.246742 1875.185671 1600.376812 1994.010655 1886.818092 1723.582951 0.92390336 1.052219072 0.804337838 1.179723651 1.175601523 1.08795789 0.92851743 1.156898572 1.094706867 1 10.75119502 -6.240375504 24.9992868 0.960276134 1.098787442 0.295443835 0.099337808 679.884992 806909.6222 0.013305503 0.022050324 5.75E-07 6.240375504 0.138511309 SREDS(ph)PELNPPPGIEDNR ddPTM_HeLa_Curcumin_4h_R1 1 SREDSPELNPPPGIEDNR 18 1 Q03164-2;Q03164;Q03164-3 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 1 0 S(0.375)REDS(0.625)PELNPPPGIEDNR 60.939 0.01183 6284200 1736 1432.2 1556.7 1936 1784.6 2367.4 1643.7 1519.9 2175.4 1919.3 TRUE FALSE FALSE 1598.593768 1555.992986 1614.392671 1927.989345 1763.319811 1876.374554 1689.817798 1983.310513 1936.764063 1985.995532 0.804933215 0.783482622 0.81288837 0.970792388 0.887877028 0.944803009 0.850866868 0.998648024 0.975210685 1 10.95564666 -4.245026714 23.19437476 0.894012871 0.99864824 0.155949963 0.074117221 2105.656281 2975578.708 0.012316311 0.394193236 5.69E-05 4.245026714 0.104635369 SRES(ph)LNVDVVK ddPTM_HeLa_Curcumin_4h_R1 3 SRESLNVDVVK 11 1 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866;H0YGB8 Q07866-6 KLC1 Kinesin light chain 1 1 0 S(0.366)RES(0.634)LNVDVVK;S(0.015)RES(0.985)LNVDVVK;S(0.088)RES(0.912)LNVDVVK ;; 85.163 0.0098518 24146100 10152.1 9083.5 8939.5 9481.7 10334.1 14425.4 11561 9713.5 10816.3 9097.3 TRUE FALSE FALSE 9348.550573 9868.637265 9270.805734 9442.467238 10210.87261 11433.40943 11885.37055 12675.10143 9629.778951 9413.430498 0.993107728 1.04835716 0.9848488 1.003084608 1.084713231 1.214584782 1.262597153 1.346491211 1.022982955 1 13.20050486 -5.131100243 1.233826993 0.998577805 1.337179031 0.96646602 0.022657126 0.057773186 0.150758533 0.003165117 0.016488056 7.39E-06 5.131100243 0.338601226 SRKTATNDVVSENANY(ph)LR ddPTM_HeLa_Curcumin_4h_R1 1 SRKTATNDVVSENANYLR 18 2 K7ENU7;H0Y9S9 K7ENU7 PPIP5K2 1 0 SRKTAT(0.003)NDVVS(0.086)ENANY(0.911)LR 70.563 0.0074732 0 716.91 681.63 667.67 650.86 564.1 749.48 529.34 441.79 458.35 460.81 TRUE FALSE FALSE 660.165817 740.5470599 692.4144375 648.1669138 557.3734759 594.0293996 544.1918558 576.4897372 408.0701517 476.8231132 1.384508844 1.553085493 1.452141095 1.359344578 1.16893133 1.245806638 1.141286655 1.209022217 0.855810342 1 8.897310359 -9.281197495 1.074202542 1.004801947 1.317631978 0.55409995 0.13339315 0.386259411 0.816468279 0.087721156 0.025182252 5.23E-10 9.281197495 0.312830032 SRLGDLYEEEMR ddPTM_HeLa_Curcumin_4h_R1 1 SRLGDLYEEEMR 12 1 P08670;B0YJC4 P08670 VIM Vimentin 0 0 148.89 0.00054021 42574000 4322.4 2385 3473.1 3614.5 2921.2 4312.8 3193.7 3687.6 4574.9 3477.5 FALSE FALSE TRUE 3980.277479 2591.148773 3601.816141 3599.544157 2886.366598 3418.276665 3283.306627 4811.932264 4073.044916 3598.342866 1.106141807 0.720095018 1.000965243 1.000333845 0.802137735 0.949958576 0.912449633 1.337263414 1.131922406 1 11.81311694 SRLS(ph)SSSSNDSGNK ddPTM_HeLa_Curcumin_4h_R1 2 SRLSSSSSNDSGNK 14 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 S(0.143)RLS(0.826)S(0.03)SSSNDSGNK;SRLS(0.889)S(0.041)S(0.068)S(0.001)SNDSGNK ; 174.4 0.0018049 12186200 3258.9 4619 3469.1 2747.6 3026.3 3986.6 2696.9 1815.91 2993.8 2827 TRUE FALSE FALSE 3000.954626 5018.245778 3597.667898 2736.231159 2990.213349 3159.734222 2772.567756 2369.5726 2665.38763 2925.23804 1.025883906 1.715499973 1.229871843 0.935387521 1.022211973 1.080163111 0.947809278 0.810044368 0.911169482 1 11.51433831 -4.153403787 1.151130215 1.080325679 0.624839326 0.153689107 0.221031527 3.42677919 3.134623208 0.034617442 1.98454125 7.02E-05 4.153403787 -0.455486352 SRLT(ph)PVS(ph)PESSSTEEK ddPTM_HeLa_Curcumin_4h_R1 3 SRLTPVSPESSSTEEK 16 1 Q13501;E7EMC7;Q13501-2 Q13501 SQSTM1 Sequestosome-1 2 0 S(0.319)RLT(0.681)PVS(0.881)PES(0.104)S(0.01)S(0.004)T(0.001)EEK;S(0.236)RLT(0.791)PVS(0.886)PES(0.056)S(0.012)S(0.015)T(0.005)EEK;S(0.529)RLT(0.669)PVS(0.727)PES(0.055)S(0.013)S(0.005)T(0.002)EEK ;; 178.99 7.71E-05 379060000 17650.5 14803.7 15541.4 15617.6 13335.9 11841.3 6772.22 6973.9 18293.4 14123.7 TRUE FALSE FALSE 16253.4443 16083.26586 16117.37796 15552.97851 13176.8781 9385.280901 6962.230267 9100.210006 16286.65979 14614.49752 1.11214527 1.100500776 1.102834903 1.064215755 0.901630595 0.642189777 0.476392038 0.622683742 1.114418047 1 13.83511261 -5.339360015 2.142353138 1.063124864 0.546503323 0.953117066 0.049858523 0.05292402 0.468395289 0.008414178 0.023974201 4.58E-06 5.339360015 -0.516621541 SRLT(ph)PVSPES(ph)SSTEEK ddPTM_HeLa_Curcumin_4h_R1 1 SRLTPVSPESSSTEEK 16 1 Q13501;E7EMC7;Q13501-2 Q13501 SQSTM1 Sequestosome-1 2 0 S(0.031)RLT(0.969)PVS(0.155)PES(0.784)S(0.056)S(0.004)T(0.001)EEK 202.96 1.19E-09 74714000 11801 9547.4 10987 9982.6 8772.4 7709 4143.8 4458.1 12345 9843.3 TRUE FALSE FALSE 10866.9384 10372.63471 11394.18789 9941.294646 8667.794859 6110.066502 4260.063876 5817.354167 10990.78439 10185.35394 1.066918092 1.018387262 1.118683548 0.976038212 0.851005759 0.599887499 0.418253887 0.571148946 1.079077315 1 13.31420849 -5.368415721 1.803445949 1.036666278 0.488412478 0.952666322 0.05154015 0.049845793 0.311211399 0.007465553 0.022581804 4.28E-06 5.368415721 -0.5482538 QPSS(ph)PGPTPR ddPTM_HeLa_Curcumin_4h_R1 4 QPSSPGPTPR 10 0 Q13424-2;Q13424 Q13424-2 SNTA1 Alpha-1-syntrophin 1 0 QPS(0.081)S(0.919)PGPTPR;QPS(0.231)S(0.769)PGPTPR;QPS(0.216)S(0.783)PGPT(0.001)PR;QPS(0.065)S(0.935)PGPTPR ;;; 137.95 0.0017956 261077000 15975.7 12609.9 12964.3 13928.4 13131.2 15072.7 10482.1 3794.67 15180.1 12985.2 TRUE FALSE FALSE 14711.20649 13699.84357 13444.76836 13870.76797 12974.61902 11946.45212 10776.19951 4951.647414 13514.88101 13436.43473 1.094874256 1.019604072 1.000620226 1.032325036 0.965629594 0.889108782 0.802013311 0.368523906 1.005838325 1 13.71386276 -4.169142878 1.065250638 1.037174031 4.22E-21 0.958727712 0.040346958 0.315501588 0.247745033 0.007069199 0.386001679 6.77E-05 4.169142878 -1.037174031 down SRLTPVS(ph)PESSSTEEK ddPTM_HeLa_Curcumin_4h_R1 5 SRLTPVSPESSSTEEK 16 1 Q13501;E7EMC7;Q13501-2 Q13501 SQSTM1 Sequestosome-1 1 0 SRLT(0.002)PVS(0.997)PESSSTEEK;S(0.003)RLT(0.338)PVS(0.634)PES(0.024)S(0.002)STEEK;S(0.211)RLT(0.107)PVS(0.667)PES(0.013)S(0.002)STEEK;SRLT(0.001)PVS(0.998)PES(0.001)SSTEEK;SRLT(0.012)PVS(0.987)PESSSTEEK ;;;; 221.81 1.25E-14 295578000 17182.81 12697.76 14957.77 14858.27 15392.5 18655.25 11668.06 12840.25 18767.7 14038.91 TRUE FALSE FALSE 15822.77246 13795.29779 15512.11811 14796.79042 15208.95449 14785.94086 11995.43436 16755.18312 16708.93026 14526.76108 1.08921544 0.949647187 1.06783047 1.018588406 1.04696115 1.01784154 0.825747343 1.153401163 1.150217187 1 13.82642545 -4.984360044 24.99647244 1.036219056 0.972629342 0.046689779 0.089604121 417.2618002 666877.9697 0.010437476 0.031299133 1.04E-05 4.984360044 -0.063589714 SRMNS(ph)LEMT(ph)PAVR ddPTM_HeLa_Curcumin_4h_R1 1 SRMNSLEMTPAVR 13 1 P09601 P09601 HMOX1 Heme oxygenase 1 2 0 S(0.006)RMNS(0.995)LEMT(0.999)PAVR 54.598 0.018568 9587300 1609.4 1498.9 1622.7 1733.4 1448 1955 1149.8 862.41 1232.1 1740.3 TRUE FALSE FALSE 1482.014292 1628.458237 1682.838689 1726.22765 1430.733546 1549.510963 1182.060293 1125.354839 1096.941713 1800.775295 0.822986797 0.904309517 0.934507872 0.958602472 0.794509759 0.860468803 0.656417431 0.624927964 0.60914969 1 10.81440245 -4.716301283 1.058241349 0.916441728 0.557531447 0.313534504 0.112167763 0.422762101 0.592399584 0.011387004 0.141741323 1.92E-05 4.716301283 -0.35891028 SGTST(ph)PTTPGSTAITPGT(ph)PPSYSSR ddPTM_HeLa_Curcumin_4h_R1 1 SGTSTPTTPGSTAITPGTPPSYSSR 25 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 2 0 S(0.025)GT(0.038)S(0.152)T(0.742)PT(0.021)T(0.023)PGS(0.003)T(0.002)AIT(0.08)PGT(0.896)PPS(0.012)YS(0.003)S(0.002)R 91.115 2.80E-05 15747000 1935.9 1514.2 1761.2 2015.7 1619 1905.4 1357.9 470.34 1788.2 1640.5 TRUE FALSE FALSE 1782.671472 1645.080701 1826.471621 2007.359567 1599.694482 1510.198562 1395.999019 613.7445008 1592.038934 1697.507253 1.050170165 0.969115565 1.075972794 1.182533721 0.942378585 0.889656618 0.82238177 0.361556335 0.937868708 1 10.72920202 -4.16895597 1.22945476 1.030178246 2.65E-19 0.878962559 0.073145802 0.39053387 0.42436566 0.010006437 0.536546879 6.78E-05 4.16895597 -1.030178246 down SRNTDEMVELR ddPTM_HeLa_Curcumin_4h_R1 5 SRNTDEMVELR 11 1 P61978-3;P61978;P61978-2;Q5T6W2;S4R457 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 0 ;;;; ;;;; 140.24 0.00026616 39885500 11552.5 8027.15 9166.3 10462.6 8934 13032.3 9378.7 10088.1 12607.8 8689.9 FALSE FALSE TRUE 10638.10743 8720.981078 9506.011141 10419.30853 8827.467885 10329.25408 9641.841081 13163.91525 11224.75588 8991.873378 1.183080209 0.969873653 1.057178048 1.158747248 0.981716213 1.148732154 1.072283903 1.463979162 1.248322281 1 13.134406 -4.260771014 24.81157517 1.079621408 1.463979293 0.611553243 0.088728807 22.80053393 846214.9025 0.011198517 0.089577854 5.49E-05 4.260771014 0.384357885 SRPFTVAASFQST(ph)SVKSPK ddPTM_HeLa_Curcumin_4h_R1 1 SRPFTVAASFQSTSVKSPK 19 2 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 SRPFTVAAS(0.001)FQS(0.137)T(0.372)S(0.372)VKS(0.118)PK 64.89 0.0064225 45657000 2029.3 1448.2 1511 1949.1 1678.5 2859 2553.7 1768.3 2214.8 1799.3 TRUE FALSE FALSE 1868.678764 1573.375955 1566.998989 1941.035141 1658.484984 2266.011172 2625.349949 2307.44653 1971.841981 1861.825541 1.003680916 0.845071635 0.841646521 1.04254405 0.890784312 1.217091034 1.410094497 1.239346265 1.059090628 1 10.86250218 -5.097415312 4.327925609 0.974604112 1.323769688 0.771754128 0.08394506 0.075895435 2.43068191 0.01159698 0.031722863 7.99E-06 5.097415312 0.349165576 SRPTSEGS(ph)DIES(ph)TEPQK ddPTM_HeLa_Curcumin_4h_R1 1 SRPTSEGSDIESTEPQK 17 1 Q4G0J3-3;Q4G0J3;H0YA82;D6RFF0 Q4G0J3-3 LARP7 La-related protein 7 2 0 S(0.002)RPT(0.004)S(0.037)EGS(0.986)DIES(0.884)T(0.087)EPQK 133.87 0.0013898 82888000 10676 9391.2 9529.2 9812.6 9767.5 10483 8080.6 5663.2 9597.9 8706.3 TRUE FALSE FALSE 9830.983335 10202.93348 9882.360535 9771.998061 9651.028942 8308.707632 8307.319888 7389.88361 8545.034383 9008.843277 1.091259225 1.132546451 1.096962199 1.084711739 1.07128392 0.922283514 0.922129471 0.820292171 0.948516266 1 13.13712616 -5.010186778 1.871394667 1.060240019 0.856953186 0.680758166 0.054720569 0.15757245 1.042136628 0.007837254 0.033272323 9.77E-06 5.010186778 -0.203286833 SRPTSEGS(ph)DIESTEPQK ddPTM_HeLa_Curcumin_4h_R1 2 SRPTSEGSDIESTEPQK 17 1 Q4G0J3-3;Q4G0J3;H0YA82;D6RFF0 Q4G0J3-3 LARP7 La-related protein 7 1 0 S(0.004)RPT(0.109)S(0.109)EGS(0.777)DIESTEPQK;SRPTSEGS(0.806)DIES(0.194)T(0.001)EPQK ; 140.12 0.00015261 309381000 9033.6 7826.8 8318.1 8193.1 8411.3 9652 8203.1 6017.9 8150.4 7087.7 TRUE FALSE FALSE 8318.581028 8503.313716 8626.376103 8159.199123 8311.000741 7650.0664 8433.256908 7852.730007 7256.321511 7333.997047 1.134249301 1.159437843 1.176217559 1.112517372 1.13321572 1.043096466 1.149885506 1.070729911 0.98940884 1 12.84038397 -9.159989922 0.90919952 0.999920753 1.123492578 0.631248078 0.03864086 0.317595682 0.472946049 0.025641574 0.007342195 6.92E-10 9.159989922 0.123571825 SRQNPQS(ph)PPQDSSVTSK ddPTM_HeLa_Curcumin_4h_R1 1 SRQNPQSPPQDSSVTSK 17 1 C9JEF4;C9J172;Q9BRX7;A0A2R8YCS4;E7EP63;E7ER52;A6NDI8;Q9UBN7 C9JEF4 HDAC6 Histone deacetylase 6 1 0 S(0.09)RQNPQS(0.85)PPQDS(0.012)S(0.043)VT(0.003)S(0.001)K 70.917 0.0073823 0 2417 2249 2194.2 1983.5 2424.6 2254.1 1796.1 1239.8 2229.6 2195 TRUE FALSE FALSE 2225.6919 2443.393539 2275.518982 1975.292803 2395.688229 1786.574251 1846.493732 1617.809313 1985.018458 2271.276087 0.979930143 1.075780066 1.001868067 0.869684145 1.054776318 0.786594929 0.812976345 0.712290911 0.873966168 1 11.14928737 -5.248157307 23.31605706 0.992161548 0.774856206 0.664180679 0.067597451 109.5364639 192284.7037 0.007477166 0.018914772 5.65E-06 5.248157307 -0.217305342 SRQPS(ph)GAGLCDISEGTVVPEDR ddPTM_HeLa_Curcumin_4h_R1 2 SRQPSGAGLCDISEGTVVPEDR 22 1 H0Y332;Q5T5C0-3;Q5T5C0-2;Q5T5C0 H0Y332 STXBP5 Syntaxin-binding protein 5 1 0 S(0.298)RQPS(0.702)GAGLCDISEGTVVPEDR;S(0.322)RQPS(0.678)GAGLCDISEGTVVPEDR ; 82.169 0.0003284 14047900 1696.64 1362.92 1714.88 1348.4 1894.41 1831.44 954.01 848.01 1923.93 1518.53 TRUE FALSE FALSE 1562.349154 1480.724732 1778.434961 1342.820678 1871.820398 1451.578699 980.776953 1106.564345 1712.879692 1571.298804 0.994304297 0.942357194 1.131824804 0.854592821 1.191256808 0.923808187 0.624182333 0.704235466 1.090104369 1 10.61774184 -4.8557848 4.688741306 1.005173887 0.665008134 0.693870995 0.094477076 0.070533201 2.638349915 0.010941405 0.035449046 1.39E-05 4.8557848 -0.340165753 SRQPS(ph)PLLLLPPPAGLTSDPGPSVR ddPTM_HeLa_Curcumin_4h_R1 2 SRQPSPLLLLPPPAGLTSDPGPSVR 25 1 I3L2J0 I3L2J0 CIC 1 0 S(0.204)RQPS(0.796)PLLLLPPPAGLTSDPGPSVR;S(0.328)RQPS(0.672)PLLLLPPPAGLTSDPGPSVR ; 75.127 0.00017692 80284000 3158.77 3073.5 2409.7 2182.06 2617.68 2891.3 2001.89 1545.4 3384.7 2785.2 TRUE FALSE FALSE 2908.750021 3339.159645 2499.005602 2173.031214 2586.465876 2291.611788 2058.057646 2016.585346 3013.406878 2881.985493 1.009286837 1.158631663 0.867112485 0.754004911 0.897459714 0.795150355 0.714111036 0.699720853 1.045600988 1 11.49284736 -6.552649532 7.514709995 1.016201976 0.78021556 0.784163209 0.068555255 0.074084026 14.59803471 0.010890934 0.015510317 2.80E-07 6.552649532 -0.235986415 SRS(ph)APPNLWAAQR ddPTM_HeLa_Curcumin_4h_R1 1 SRSAPPNLWAAQR 13 1 Q92934;F5H3B1;F5H1R6 Q92934 BAD Bcl2-associated agonist of cell death 1 0 S(0.211)RS(0.789)APPNLWAAQR 70.563 0.015258 6831100 1748.4 1835.4 1969.3 1811.6 1707.7 2137.3 1770.9 1651.2 2167.1 2373.3 TRUE FALSE FALSE 1610.012295 1994.043798 2042.28399 1804.104079 1687.336793 1693.999888 1820.586688 2154.643279 1929.374552 2455.771998 0.655603328 0.811982464 0.83162606 0.734638265 0.687090167 0.689803406 0.741350048 0.877379203 0.785648893 1 11.26196091 -9.439210595 1.097297513 1.004153475 0.743899088 0.120160325 0.092559786 0.261418142 0.548420942 0.053565355 0.012541292 3.64E-10 9.439210595 -0.260254387 SRS(ph)DIDVNAAAGAK ddPTM_HeLa_Curcumin_4h_R1 3 SRSDIDVNAAAGAK 14 1 E3W994;J3KR49;O75122;E7ERI8;E7EW49;O75122-3;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2 E3W994 CLASP2 CLIP-associating protein 2 1 0 S(0.293)RS(0.707)DIDVNAAAGAK;S(0.47)RS(0.53)DIDVNAAAGAK;S(0.064)RS(0.936)DIDVNAAAGAK ;; 165.17 9.46E-05 711101100 21251.9 16983.7 18021.6 19516.2 18875.5 20447.2 15768.5 13693.3 20595.4 19144.7 TRUE FALSE FALSE 19569.78969 18451.69535 18689.49635 19435.44714 18650.42199 16206.22023 16210.92167 17868.32413 18336.13615 19809.9769 0.987875442 0.931434471 0.943438574 0.981093882 0.941466115 0.818083752 0.818321079 0.901986117 0.925601087 1 14.27393958 -5.429965694 3.535514835 0.983483393 0.843809637 0.648979605 0.035901314 0.082959518 1.93307549 0.004866903 0.011415406 3.72E-06 5.429965694 -0.139673756 SRS(ph)DVDMDPSSATAVLGPAR ddPTM_HeLa_Curcumin_4h_R1 1 SRSDVDMDPSSATAVLGPAR 20 1 M0QZR4;M0QZH8;M0QYS3;M0QYC1 M0QZR4 ARHGEF1 1 0 S(0.083)RS(0.657)DVDMDPS(0.249)S(0.009)AT(0.002)AVLGPAR 91.926 0.0019981 6468000 1666.3 1203.7 1523.5 1707.9 1818.4 1665.7 1335.9 752.01 1657.3 1459.6 TRUE FALSE FALSE 1534.410597 1307.742464 1579.96225 1700.833162 1796.716768 1320.215044 1373.381759 981.2943872 1475.498336 1510.320991 1.01594999 0.865870548 1.046110237 1.126140186 1.189625767 0.874128779 0.909331041 0.649725716 0.97694354 1 10.56063949 -4.238967821 1.458946455 1.016717707 0.497999555 0.602060321 0.090879252 0.657165466 1.195468618 0.013192054 0.501022641 5.77E-05 4.238967821 -0.518718152 SRS(ph)ESETSTMAAK ddPTM_HeLa_Curcumin_4h_R1 1 SRSESETSTMAAK 13 1 A0A087WVF1;Q96B23-2;Q96B23 A0A087WVF1 C18orf25 Uncharacterized protein C18orf25 1 0 S(0.035)RS(0.748)ES(0.216)ETSTMAAK 126.42 0.0008369 37731000 6379.5 5895.4 5765.7 6228.2 5656.2 6244.6 4276.1 3704.4 6041.7 5551.3 TRUE FALSE FALSE 5874.555843 6404.972107 5979.381914 6202.429359 5588.753509 4949.399569 4396.075857 4833.854507 5378.940626 5744.207262 1.022692179 1.115031512 1.040941185 1.079771164 0.972937301 0.86163318 0.765305926 0.841518122 0.936411306 1 12.48789209 -5.250054093 2.586449944 1.02644575 0.804919495 0.789830577 0.048662727 0.082065167 1.075927421 0.006222751 0.017685048 5.62E-06 5.250054093 -0.221526255 SRS(ph)FSGLIK ddPTM_HeLa_Curcumin_4h_R1 1 SRSFSGLIK 9 1 Q14CB8-4;Q14CB8-6;Q14CB8-7;Q14CB8-3;Q14CB8;Q14CB8-2 Q14CB8-4 ARHGAP19 Rho GTPase-activating protein 19 1 0 SRS(0.985)FS(0.015)GLIK 85.973 0.01079 10222000 1569.1 1147 1426.4 1784.7 1427.3 2275.6 1751 916.01 1782.9 1791 TRUE FALSE FALSE 1444.904079 1246.141569 1479.263639 1777.315384 1410.28038 1803.614909 1800.128347 1195.297232 1587.320331 1853.237117 0.77966498 0.672413453 0.798205273 0.95903291 0.760982158 0.973224037 0.971342701 0.644978034 0.856512271 1 10.85583177 -9.330835507 1.106817618 0.997970705 0.824638745 0.069751524 0.119209275 0.54845806 1.223716217 0.071304696 0.019703962 4.67E-10 9.330835507 -0.17333196 SRS(ph)FSSSAEEHS ddPTM_HeLa_Curcumin_4h_R1 1 SRSFSSSAEEHS 12 1 Q96EQ0 Q96EQ0 SGTB Small glutamine-rich tetratricopeptide repeat-containing protein beta 1 0 S(0.019)RS(0.98)FSSSAEEHS 140.45 0.011289 10690000 1844.8 1714.5 1468.7 1807 2121.7 2894 1500.7 1053.3 2501.9 1843.9 TRUE FALSE FALSE 1698.782133 1862.69374 1523.131314 1799.523113 2096.400113 2293.751778 1542.805603 1374.446321 2227.447829 1907.975388 0.890358515 0.976267174 0.79829715 0.943158452 1.098756371 1.202191492 0.808608755 0.720369 1.167440547 1 10.89782685 -11.16487644 0.007348739 1.949482462 2.20E-06 0.058722301 0.148546593 58822.70615 56.33921996 7965.895596 7006.276851 6.84E-12 11.16487644 -1.949480262 SRS(ph)FTLDDESLK ddPTM_HeLa_Curcumin_4h_R1 1 SRSFTLDDESLK 12 1 Q86WR7;Q86WR7-2;X6RHS9 Q86WR7 PROSER2 Proline and serine-rich protein 2 1 0 S(0.09)RS(0.906)FT(0.004)LDDESLK 122.16 0.0014622 59275000 6424.6 5509.9 5799.8 5675.8 5656.3 6002.1 5350.7 3873.9 6289.7 5432.1 TRUE FALSE FALSE 5916.086131 5986.151204 6014.74569 5652.315043 5588.852317 4757.196802 5500.826241 5055.034277 5599.735646 5620.865071 1.052522353 1.064987529 1.070074733 1.005595219 0.994304657 0.846346024 0.978644065 0.899333859 0.996240895 1 12.45657647 -5.479016823 4.642931124 1.030505424 0.914644075 0.666792357 0.038861733 0.098580416 4.766693073 0.005638025 0.012619485 3.32E-06 5.479016823 -0.115861349 SRS(ph)FTSSYAISAANHVK ddPTM_HeLa_Curcumin_4h_R1 1 SRSFTSSYAISAANHVK 17 1 Q14432 Q14432 PDE3A "cGMP-inhibited 3,5-cyclic phosphodiesterase A" 1 0 S(0.115)RS(0.368)FT(0.069)S(0.069)S(0.368)Y(0.011)AISAANHVK 108.25 0.00056549 24090000 2493.1 1229.2 1712 1590.7 1757 3660.4 1758.7 590.33 1883.9 1695.8 TRUE FALSE FALSE 2295.768504 1335.446571 1775.448226 1584.118105 1736.048923 2901.191779 1808.044389 770.3188995 1677.240883 1754.728924 1.308332286 0.761055769 1.011807694 0.90277084 0.98935448 1.653356105 1.030383875 0.438995955 0.95584045 1 10.77703246 -7.28074853 24.94421292 1.145601346 0.998109479 0.015271146 0.298703244 2093.049952 2703866.401 0.052070007 0.059592346 5.24E-08 7.28074853 -0.147491867 TDASSASS(ph)FLDSDELER ddPTM_HeLa_Curcumin_4h_R1 3 TDASSASSFLDSDELER 17 0 G3XAC6;Q14498-2;Q14498;H0Y4X3;Q14498-3;A0A0U1RQW2;A0A0U1RQH7 G3XAC6 RBM39 RNA-binding protein 39 1 0 TDASSAS(0.016)S(0.984)FLDSDELER;TDASSAS(0.001)S(0.999)FLDSDELER;TDAS(0.002)S(0.007)AS(0.18)S(0.797)FLDS(0.014)DELER ;; 405.9 2.45E-275 49636000 6552.68 5699.59 6271.8 6525.82 6524 9138.8 8649.5 12262.9 6862.4 5921.54 TRUE FALSE FALSE 6034.028464 6192.237163 6504.238425 6498.817886 6446.205561 7243.309864 8892.181691 16001.80176 6109.611889 6127.313074 0.984775609 1.01059585 1.061515602 1.06063095 1.052044425 1.182134775 1.451236714 2.611552823 0.997111102 1 12.58103885 -3.606868229 1.10035346 1.004013741 7.014731542 0.994007041 0.036825335 0.3272931 0.113858688 0.006153546 3.248517485 0.000247247 3.606868229 6.0107178 up SRS(ph)LSNSNPDISGTPTSPDDEVR ddPTM_HeLa_Curcumin_4h_R1 1 SRSLSNSNPDISGTPTSPDDEVR 23 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 S(0.125)RS(0.395)LS(0.395)NS(0.086)NPDISGTPTSPDDEVR 81.696 0.00021553 6963900 491.01 433.43 553.23 460.88 259.83 586.16 764.75 568.49 442.92 510.37 TRUE FALSE FALSE 452.1460404 470.8937579 573.7331905 458.9730007 256.731697 464.5838086 786.2068268 741.819984 394.3327841 528.1053195 0.856166419 0.891666379 1.086399188 0.86909369 0.486137305 0.879718101 1.488731126 1.404681901 0.746693452 1 9.044681863 -4.762840306 24.99504602 0.899702408 1.446706659 0.689890747 0.156904928 15.26530365 272387.887 0.022244414 0.072528353 1.73E-05 4.762840306 0.547004251 SRS(ph)PAVNGENK ddPTM_HeLa_Curcumin_4h_R1 1 SRSPAVNGENK 11 1 Q8IZD2-8;Q8IZD2-6;Q8IZD2-5;Q8IZD2-2;Q8IZD2-7;Q8IZD2 Q8IZD2-8 KMT2E Histone-lysine N-methyltransferase 2E 1 0 S(0.007)RS(0.993)PAVNGENK 73.666 0.015528 2274400 878.99 1093.7 1016.5 672.43 879.3 927.78 538.36 207.76 600.57 672.74 TRUE FALSE FALSE 809.417014 1188.234555 1054.172384 669.6476628 868.8149218 735.3479698 553.4649327 271.1050676 534.6889736 696.1176649 1.162758905 1.706944981 1.514359479 0.961974816 1.248086301 1.056355853 0.795073822 0.389452935 0.76810143 1 9.443187376 -4.408088292 1.574092615 1.162825424 0.225978424 0.494225625 0.25534777 0.525842658 1.502484091 0.036585616 0.690178482 3.91E-05 4.408088292 -0.936846999 SRS(ph)PES(ph)QVIGENTK ddPTM_HeLa_Curcumin_4h_R1 1 SRSPESQVIGENTK 14 1 O95218-2 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 2 0 S(0.017)RS(0.983)PES(1)QVIGENTK 106.35 0.014077 6764800 3811.4 3002.7 3676.4 3526.2 3995.6 4100.8 3613.3 3108.3 3372 2867.2 TRUE FALSE FALSE 3509.723668 3262.240008 3812.650618 3511.609519 3947.95508 3250.247854 3714.679473 4056.006361 3002.100036 2966.834987 1.182985803 1.099569077 1.285090217 1.183621447 1.330695875 1.095527007 1.25206811 1.367115589 1.011886421 1 11.53470897 -13.52287875 0.113010182 0.214926129 1.362211321 0.610990934 0.075938841 48.55981126 0.40113231 8.708707843 0.418450714 3.00E-14 13.52287875 1.147285192 SRS(ph)PES(ph)QVIGENTKQP ddPTM_HeLa_Curcumin_4h_R1 1 SRSPESQVIGENTKQP 16 2 O95218-2 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 2 0 S(0.277)RS(0.725)PES(0.964)QVIGENT(0.034)KQP 104.78 0.0051148 121610000 3533.9 2688 2532.9 2726.2 3044.9 3588.9 2808.4 2621.4 3184.7 2935.1 TRUE FALSE FALSE 3254.188086 2920.338743 2626.771502 2714.919707 3008.591556 2844.521685 2887.196146 3420.652793 2835.346378 3037.094507 1.07148068 0.961556756 0.864896201 0.893920061 0.99061506 0.936593076 0.950644157 1.126291192 0.933571995 1 11.56847609 -7.179128083 7.455069599 1.03369968 0.953936718 0.003078173 0.074508606 0.320915164 25.78980932 0.01154837 0.014156968 6.62E-08 7.179128083 -0.079762962 LSPLPPGS(ph)PGSAAR ddPTM_HeLa_Curcumin_4h_R1 2 LSPLPPGSPGSAAR 14 0 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 0 LSPLPPGS(0.97)PGS(0.03)AAR;LSPLPPGS(0.845)PGS(0.155)AAR ; 206.67 3.49E-09 24086300 2702.4 1876.46 2194.5 2724.5 3076.9 5192.8 3916 4747.9 2945.6 2437.6 TRUE FALSE FALSE 2488.502188 2038.652841 2275.8301 2713.226741 3040.209977 4115.754745 4025.872421 6195.512853 2622.47505 2522.306419 0.986597889 0.808249476 0.902281374 1.075692755 1.205329358 1.631742565 1.596107591 2.456288739 1.039713109 1 11.30052783 -3.591572299 0.626982454 0.966099977 4.972865014 0.937446999 0.118400851 1.084820036 0.161889121 0.020582967 3.794688309 0.000256111 3.591572299 4.006765037 up SRS(ph)PGSPVGEGTGSPPK ddPTM_HeLa_Curcumin_4h_R1 1 SRSPGSPVGEGTGSPPK 17 1 E7EV99;E7ENY0;P35611-5;P35611-2;P35611-6;P35611-4;P35611;P35611-3;A0A0A0MSR2;H0Y9H2 E7EV99 ADD1 Alpha-adducin 1 0 S(0.328)RS(0.619)PGS(0.027)PVGEGT(0.001)GS(0.025)PPK 62.005 0.013695 70961000 7811.3 7404.3 7483.8 8020.4 7316.5 10180 7867.6 5526.5 7927.3 8122.7 TRUE FALSE FALSE 7193.027363 8044.294699 7761.156211 7987.21371 7229.255516 8068.553248 8088.343681 7211.504409 7057.695023 8404.96322 0.855807119 0.957088626 0.923401567 0.950297283 0.860117448 0.959974843 0.962329456 0.858005469 0.83970564 1 13.03702579 -9.605362262 1.414598374 0.999869624 0.910788607 0 0.064534714 0.36400183 1.31031679 0.030453448 0.007067417 2.48E-10 9.605362262 -0.089081017 SRS(ph)PLELEPEAK ddPTM_HeLa_Curcumin_4h_R1 4 SRSPLELEPEAK 12 1 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 0 S(0.003)RS(0.997)PLELEPEAK;S(0.052)RS(0.948)PLELEPEAK;S(0.016)RS(0.984)PLELEPEAK;S(0.057)RS(0.943)PLELEPEAK ;;; 146.27 0.00034917 3004939000 30231.9 23593 27347.9 27655 27433.8 32187.5 27266.9 22509.3 31528.9 27231.5 TRUE FALSE FALSE 27839.01321 25632.27379 28361.43723 27540.57094 27106.66985 25511.44967 28031.93583 29372.28195 28070.25855 28177.7926 0.987977079 0.909662235 1.006517353 0.977385679 0.961986989 0.905374315 0.994823698 1.042391161 0.996183731 1 14.78227098 -7.501861307 21.20630113 0.994695917 0.96921972 0.072387826 0.03895306 63.70948382 64286.16949 0.006747228 0.007251547 3.15E-08 7.501861307 -0.025476197 SRS(ph)PLELEPEAKK ddPTM_HeLa_Curcumin_4h_R1 2 SRSPLELEPEAKK 13 2 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 1 0 S(0.111)RS(0.889)PLELEPEAKK;S(0.088)RS(0.912)PLELEPEAKK ; 128.71 0.0012555 149737000 9264.1 6933.3 7728.7 8121.6 7123.4 9212.6 6599.2 5051.3 10682.1 8291.7 TRUE FALSE FALSE 8530.83671 7532.583558 8015.132421 8087.994971 7038.458107 7301.802913 6784.355791 6591.418117 9510.300355 8579.835958 0.994289023 0.877940277 0.934182479 0.94267478 0.820348797 0.851042252 0.790732576 0.768245238 1.108447807 1 13.06673435 -5.390340309 0.389203078 1.007595431 0.700891165 0.793206049 0.04617056 0.649675651 0.122311176 0.010935569 0.082236977 4.07E-06 5.390340309 -0.306704266 SRS(ph)PLLVTVVESDPRPQGQPR ddPTM_HeLa_Curcumin_4h_R1 2 SRSPLLVTVVESDPRPQGQPR 21 2 A0A2R8YH03;Q5VWN6;Q5VWN6-2 A0A2R8YH03 FAM208B Protein FAM208B 1 0 S(0.084)RS(0.873)PLLVT(0.007)VVES(0.035)DPRPQGQPR;S(0.097)RS(0.805)PLLVT(0.05)VVES(0.048)DPRPQGQPR ; 66.702 0.0028643 35537000 1421.35 947.83 806.72 1002.1 1002.82 1101.8 765.1 301.22 1090.35 1018.6 TRUE FALSE FALSE 1308.848648 1029.756202 836.6177529 997.9535757 990.8620265 873.2742602 786.5666468 393.0605914 970.7413329 1053.996274 1.241796276 0.977001748 0.79375779 0.946828371 0.940100122 0.828536382 0.746270804 0.37292408 0.921010213 1 10.04165405 -4.183400918 0.49206494 1.09780571 1.95E-14 0.654406407 0.124631729 1.969465391 0.302391966 0.029708913 1.268059949 6.56E-05 4.183400918 -1.09780571 SRS(ph)PPT(ph)S(ph)ELMMK ddPTM_HeLa_Curcumin_4h_R1 1 SRSPPTSELMMK 12 1 Q9HC77;F6VUX8;Q9HC77-2 Q9HC77 CENPJ Centromere protein J 3 0 S(0.438)RS(0.726)PPT(0.872)S(0.963)ELMMK 46.68 0.019701 1754300 1199.8 2169 1409.9 1574.8 1131.5 1522.3 1542.6 898.13 1585.3 2280.4 TRUE FALSE FALSE 1104.834564 2356.478695 1462.152134 1568.283895 1118.007602 1206.55782 1585.881204 1171.965703 1411.396556 2359.64373 0.468220922 0.998658681 0.619649532 0.664627407 0.473803561 0.511330505 0.67208502 0.496670615 0.598139684 1 11.20435334 -9.474440653 1.02725163 1.017213391 0.606222121 0 0.192337408 0.404598624 0.709573185 0.129497539 0.02680293 3.35E-10 9.474440653 -0.41099127 SRS(ph)PVDLR ddPTM_HeLa_Curcumin_4h_R1 2 SRSPVDLR 8 1 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 1 0 S(0.218)RS(0.782)PVDLR;S(0.231)RS(0.769)PVDLR ; 69.65 0.019391 146248000 4446.5 2863 3700.7 3659.1 4068.5 4502.2 3554.6 14149.8 4155.9 3374.5 TRUE FALSE FALSE 4094.554833 3110.464963 3837.851197 3643.959614 4019.985795 3568.39297 3654.332509 18464.00888 3700.008168 3491.763624 1.172632307 0.890800552 1.099115407 1.04358714 1.151276612 1.021945743 1.046557815 5.287874802 1.059638786 1 11.76974018 -4.261263654 24.99999242 1.06789924 5.28787605 0.996411576 0.076220764 0.61120415 86884.31637 0.011602919 0.090076493 5.48E-05 4.261263654 4.21997681 SRS(ph)S(ph)S(ph)VGSSSSYPISPAVSR ddPTM_HeLa_Curcumin_4h_R1 2 SRSSSVGSSSSYPISPAVSR 20 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 3 0 S(0.182)RS(0.608)S(0.826)S(0.904)VGS(0.38)S(0.028)S(0.034)S(0.028)YPIS(0.009)PAVSR;S(0.023)RS(0.981)S(0.996)S(0.999)VGSSSSYPISPAVSR ; 117.2 0.00065132 27360000 6241.09 4790.36 5352.74 6046.7 6118.2 7035 5740.17 4941 6276.8 5522.3 TRUE FALSE FALSE 5747.101141 5204.417373 5551.117253 6021.680358 6045.244461 5575.861699 5901.223721 6447.488154 5588.250744 5714.199514 1.005757872 0.91078678 0.971460174 1.053809959 1.05793374 0.975790517 1.03272973 1.128327448 0.977958633 1 12.48033569 -6.253103625 24.40917573 0.992299303 1.04512379 0.392787662 0.044325793 516.1667196 1511466.208 0.006864938 0.011253079 5.58E-07 6.253103625 0.052824487 GKPPPLLPSVLGPAGGDREALGLGPPAAQLT(ph)PPPAPVGLR ddPTM_HeLa_Curcumin_4h_R1 1 GKPPPLLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLR 40 2 A0A087WZ13;E9PAU2;Q8IY67-2;Q8IY67 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 0 GKPPPLLPSVLGPAGGDREALGLGPPAAQLT(1)PPPAPVGLR 72.433 5.88E-07 15033000 852.98 580.58 816.35 657.4 771.02 1373.6 1403.3 2254.9 782.36 615.25 TRUE FALSE FALSE 785.4657329 630.7627482 846.6046491 654.679853 761.8260901 1088.699876 1442.672821 2942.40863 696.5370654 636.6298917 1.233787077 0.990784059 1.329822335 1.028352362 1.196654603 1.710098584 2.266109148 4.621851201 1.094100473 1 9.314311087 -3.555116205 0.972031474 1.109064789 14.19749154 0.98626418 0.124302793 0.515706192 0.139992707 0.020145847 9.868954998 0.000278538 3.555116205 13.08842675 up SRS(ph)TTELDDYSTNK ddPTM_HeLa_Curcumin_4h_R1 1 SRSTTELDDYSTNK 14 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 S(0.264)RS(0.72)T(0.016)TELDDYSTNK 216.26 7.26E-13 14276000 3376.5 3078.9 3532.8 3525.2 3455.9 4749.3 3578.5 4720.2 3735.8 3263.7 TRUE FALSE FALSE 3109.246462 3345.026397 3663.728676 3510.613656 3414.69065 3764.241644 3678.903079 6159.367251 3325.992087 3377.113332 0.920681705 0.990498709 1.084869922 1.039530899 1.011127053 1.114632905 1.089363227 1.823855656 0.984862443 1 11.72157488 -1.861915742 1.109430466 0.982152718 200 0.942039097 0.059125121 63.19957063 0.420770808 0.009814184 31605.21735 0.013743086 1.861915742 199.0178473 SRS(ph)TTELDDYSTNKNGNNK ddPTM_HeLa_Curcumin_4h_R1 1 SRSTTELDDYSTNKNGNNK 19 2 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 S(0.056)RS(0.861)T(0.035)T(0.035)ELDDY(0.013)S(0.001)TNKNGNNK 106.47 0.00045161 19318000 1369.3 1165 834.59 1131.1 721.68 1217.3 1152.2 1662.2 1795.1 1242.1 TRUE FALSE FALSE 1260.91846 1265.697409 865.5206396 1126.419808 713.0744373 964.8182582 1184.527631 2168.997128 1598.182021 1285.262883 0.981058799 0.984777065 0.673419151 0.876411996 0.55480824 0.750677757 0.921622842 1.687590265 1.243467031 1 10.32784776 -4.261747847 7.890188072 0.912843163 1.694248391 0.626686716 0.184357957 0.045816026 33.1375116 0.024143473 0.190888435 5.47E-05 4.261747847 0.781405227 SRS(ph)WEDSPER ddPTM_HeLa_Curcumin_4h_R1 1 SRSWEDSPER 10 1 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;A0A3B3IRI3;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISZ5;Q9UDY2-5;A0A3B3IRV6;A0A3B3ISF1;A0A3B3IU26;B1AN86 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 S(0.055)RS(0.945)WEDSPER 103.97 0.0044593 44224000 1066.6 1001.1 774.95 990.08 795.15 1094.2 791.18 1670.1 1010.1 1011 TRUE FALSE FALSE 982.1774845 1087.630623 803.6703287 985.9833113 785.6683556 867.2505858 813.3783814 2179.305802 899.2945571 1046.132175 0.938865574 1.039668456 0.768230199 0.942503572 0.751022074 0.829006704 0.777510147 2.083203112 0.859637605 1 10.03084943 -4.25695954 24.99765627 0.925897242 2.083203574 0.92112497 0.104936266 96.71177949 539635.5895 0.015415976 0.163964837 5.53E-05 4.25695954 1.157306333 SRSESDLSQPES(ph)DEEGYALSGR ddPTM_HeLa_Curcumin_4h_R1 1 SRSESDLSQPESDEEGYALSGR 22 1 Q15751;H0YNB1 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 0 SRSESDLSQPES(0.936)DEEGYALS(0.064)GR 99.148 5.83E-05 8102900 916.25 799.46 811.88 878.52 896.26 896.51 701.52 541.7 655.81 709.72 TRUE FALSE FALSE 843.7278457 868.5617601 841.968987 874.884917 885.5726849 710.5637202 721.2027632 706.8618363 583.8692838 734.3827172 1.148893929 1.182709968 1.146498913 1.191320134 1.205873537 0.967565962 0.982053017 0.962525152 0.795047691 1 9.520388297 -5.226800992 24.14916194 1.103458221 0.97184846 0.194297665 0.11594672 376.5802677 262542.9583 0.012172527 0.031031632 5.93E-06 5.226800992 -0.131609762 SRSFTSS(ph)YAISAANHVK ddPTM_HeLa_Curcumin_4h_R1 1 SRSFTSSYAISAANHVK 17 1 Q14432 Q14432 PDE3A "cGMP-inhibited 3,5-cyclic phosphodiesterase A" 1 0 S(0.211)RS(0.211)FT(0.032)S(0.052)S(0.349)Y(0.144)AISAANHVK 87.654 0.0023955 27682000 1803.3 1258.2 1642.5 1447.7 1520.6 3121.3 2052.4 766.48 2179.7 1790.5 TRUE FALSE FALSE 1660.566902 1366.953202 1703.372495 1441.709801 1502.467838 2473.907196 2109.98482 1000.176224 1940.592363 1852.719742 0.896286073 0.737808947 0.919390265 0.7781586 0.810952571 1.335284091 1.138858065 0.539842158 1.047428988 1 10.85542895 -4.242808388 23.65067979 0.947935019 0.539841402 0.350682804 0.171558844 1760.243829 2234427.024 0.023876293 1.001867346 5.72E-05 4.242808388 -0.408093617 SRSLS(ph)NS(ph)NPDISGTPTSPDDEVR ddPTM_HeLa_Curcumin_4h_R1 2 SRSLSNSNPDISGTPTSPDDEVR 23 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 2 0 S(0.01)RS(0.191)LS(0.834)NS(0.965)NPDISGTPTSPDDEVR;S(0.018)RS(0.266)LS(0.762)NS(0.954)NPDISGTPTSPDDEVR ; 121.14 3.67E-06 40065000 3437.4 2421.93 2881.26 3218.45 3125.67 4018.6 4089.1 2445.75 3398.1 3041.5 TRUE FALSE FALSE 3165.326163 2631.270837 2988.04203 3205.132907 3088.398427 3185.097061 4203.829141 3191.447916 3025.336932 3147.191899 1.005762046 0.836069398 0.949431152 1.018410383 0.981318752 1.012044122 1.335739693 1.014062065 0.961281367 1 11.61984943 -4.939059963 13.12435567 0.986234179 1.174867619 0.45684361 0.088258332 0.657271872 140.2062586 0.011208006 0.033638396 1.15E-05 4.939059963 0.18863344 SRSLSNS(ph)NPDISGTPTSPDDEVR ddPTM_HeLa_Curcumin_4h_R1 2 SRSLSNSNPDISGTPTSPDDEVR 23 1 Q96N67-2;Q96N67-6;Q96N67;Q96N67-4;Q96N67-3;Q96N67-5;A0A0U1RRC1;A0A0U1RQJ5 Q96N67-2 DOCK7 Dedicator of cytokinesis protein 7 1 0 S(0.038)RS(0.157)LS(0.157)NS(0.648)NPDISGTPTSPDDEVR;S(0.019)RS(0.05)LS(0.05)NS(0.88)NPDISGTPTSPDDEVR ; 129.77 3.44E-06 22526400 2504.4 1741.91 2425.2 2568 2360.7 3059.8 2890.9 2606.7 2190.92 2125.75 TRUE FALSE FALSE 2306.174097 1892.472939 2515.080045 2557.374296 2332.550194 2425.162989 2972.010874 3401.47083 1950.581557 2199.619654 1.048442213 0.860363716 1.143415881 1.162643865 1.060433421 1.102537425 1.351147626 1.546390451 0.886781291 1 11.10303837 -1.000000001 0.532400809 1.016758431 23.23013427 0.799532567 0.087582135 31.12576112 0.273712028 0.014388421 788.9063306 0.1 1.000000001 22.21337584 EALGLGPPAAQLT(ph)PPPAPVGLR ddPTM_HeLa_Curcumin_4h_R1 2 EALGLGPPAAQLTPPPAPVGLR 22 0 A0A087WZ13;E9PAU2;Q8IY67-2;Q8IY67 A0A087WZ13 RAVER1 Ribonucleoprotein PTB-binding 1 1 0 EALGLGPPAAQLT(1)PPPAPVGLR;EALGLGPPAAQLT(1)PPPAPVGLR ; 189.11 1.94E-12 93732000 1043.89 781.79 1111.01 833.13 1500.41 1672.32 2043.03 3498.8 839.87 1065.35 TRUE FALSE FALSE 961.265005 849.364444 1152.185008 829.6827288 1482.518591 1325.461981 2100.351923 4565.568014 747.7383623 1102.370833 0.871997858 0.770488858 1.045188219 0.75263487 1.344845624 1.202373957 1.905304331 4.141589995 0.678300205 1 10.10639391 -3.531454352 1.04215078 0.931130769 14.14946392 0.970980235 0.167832382 0.650679688 0.18532879 0.021511717 13.83150332 0.000294134 3.531454352 13.21833315 up RDS(ph)ELGPGVK ddPTM_HeLa_Curcumin_4h_R1 2 RDSELGPGVK 10 1 O95466;O95466-2;O95466-3;K7EK60;A0A0A0MR62 O95466 FMNL1 Formin-like protein 1 1 0 RDS(1)ELGPGVK;RDS(1)ELGPGVK ; 91.712 0.0084728 42306000 4732.2 3916.7 4703.4 4746.9 5017.5 7267.1 6897.5 8773.7 4443.7 4731.9 TRUE FALSE FALSE 4357.641377 4255.242096 4877.712142 4727.258586 4957.66959 5759.821543 7091.025286 11448.76074 3956.237228 4896.333173 0.889980568 0.869067105 0.996196944 0.965469142 1.01252701 1.176354088 1.448231776 2.338231558 0.808000005 1 12.25748601 -3.524185936 0.918784401 0.943053288 6.186256724 0.980556384 0.060204217 0.549366303 0.132200723 0.008269946 3.994231042 0.000299098 3.524185936 5.243203436 up SRSS(ph)S(ph)VGSSSSYPISPAVSR ddPTM_HeLa_Curcumin_4h_R1 2 SRSSSVGSSSSYPISPAVSR 20 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 S(0.027)RS(0.404)S(0.691)S(0.834)VGS(0.023)S(0.007)S(0.006)S(0.005)Y(0.003)PISPAVSR;S(0.193)RS(0.237)S(0.752)S(0.818)VGSSSSYPISPAVSR ; 102.21 0.00031373 19238000 1684.3 1443.52 1451.48 1589.52 1802.69 1899.14 1385.12 1771.36 1927.9 1656.11 TRUE FALSE FALSE 1550.985878 1568.291437 1505.273126 1582.942987 1781.194099 1505.236956 1423.982739 2311.43951 1716.414193 1713.659699 0.905072272 0.915170869 0.878396759 0.923720729 1.039409458 0.878375652 0.830960044 1.348832274 1.001607375 1 10.74286493 -4.252071825 24.95540957 0.938741248 1.348832496 0.80243934 0.062173883 426.6532159 1136591.403 0.008910802 0.151404141 5.60E-05 4.252071825 0.410091247 SRSS(ph)SVGSSSSYPISPAVSR ddPTM_HeLa_Curcumin_4h_R1 1 SRSSSVGSSSSYPISPAVSR 20 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 S(0.006)RS(0.099)S(0.884)S(0.011)VGSSSSYPISPAVSR 120.15 0.00056345 0 933.2 698.04 614.64 996.44 819.05 852.79 575.48 645.08 987.43 719.98 TRUE FALSE FALSE 859.3362353 758.3754672 637.4190991 992.3169953 809.2833637 675.9117411 591.62642 841.7619224 879.1113994 744.9992514 1.153472616 1.01795467 0.855596966 1.33197046 1.086287486 0.907264994 0.794130221 1.12988291 1.180016487 1 9.541095166 -5.263660268 24.6990007 1.073912654 0.928796455 0.174385049 0.141288803 209.7408412 2332596.586 0.019314728 0.045246991 5.45E-06 5.263660268 -0.145116199 SRST(ph)TELDDYSTNK ddPTM_HeLa_Curcumin_4h_R1 1 SRSTTELDDYSTNK 14 1 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 S(0.058)RS(0.083)T(0.851)T(0.008)ELDDYSTNK 217.32 6.42E-13 80263000 4323.8 4123.1 4411.3 4482.8 4969.5 4763.8 4237 6100.7 4697.6 4277 TRUE FALSE FALSE 3981.566668 4479.482392 4574.786659 4464.251361 4910.241958 3775.734181 4355.878817 7960.775346 4182.285033 4425.625432 0.899661919 1.012169344 1.033703988 1.00872779 1.109502382 0.853152676 0.984240281 1.798791034 0.945015591 1 12.11166564 -4.261818683 7.031172447 0.969847177 1.810731799 0.92716255 0.068527386 0.020259782 7.721207554 0.009981725 0.080833488 5.47E-05 4.261818683 0.840884622 SRSTTELDDY(ph)STNKNGNNK ddPTM_HeLa_Curcumin_4h_R1 1 SRSTTELDDYSTNKNGNNK 19 2 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 S(0.013)RS(0.126)T(0.126)T(0.126)ELDDY(0.56)S(0.041)T(0.006)NKNGNNK 75.143 0.0073016 3753900 787.01 839.41 635.6 740.61 627.41 658.67 326.08 682.61 841 820.88 TRUE FALSE FALSE 724.7173281 911.9648601 659.1558951 737.5455521 619.9285455 522.0544173 335.2289272 890.7346467 748.7444041 849.4055189 0.853205344 1.073650735 0.776020264 0.868307935 0.729838142 0.61461152 0.394662996 1.048656533 0.881492276 1 9.730309672 -5.941799719 1.429912589 0.935408565 0.659811025 0.281445065 0.167238553 0.332277885 1.356939825 0.025225162 0.056375669 1.14E-06 5.941799719 -0.27559754 SRSTTELDDYS(ph)TNKNGNNK ddPTM_HeLa_Curcumin_4h_R1 1 SRSTTELDDYSTNKNGNNK 19 2 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 S(0.018)RS(0.218)T(0.018)T(0.013)ELDDY(0.24)S(0.295)T(0.196)NKNGNNK 66.068 0.0093234 6220500 948.14 761.41 838 873.94 649.47 1034.5 801.13 1048.3 1459.4 1455.9 TRUE FALSE FALSE 873.0937185 827.2228876 869.0570172 870.3238678 641.7254944 819.9330388 823.6075517 1367.921844 1299.307471 1506.492417 0.579554008 0.549105245 0.576874472 0.577715399 0.425973266 0.54426629 0.546705408 0.908017743 0.862471963 1 10.5569777 -9.094534803 0.716852845 1.021827936 0.574954093 0.540386092 0.123429428 0.375049961 0.326685948 0.097770539 0.024296743 8.04E-10 9.094534803 -0.446873843 S(ph)PSLSPSPPS(ph)PLEK ddPTM_HeLa_Curcumin_4h_R1 1 SPSLSPSPPSPLEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 S(0.924)PS(0.016)LS(0.06)PS(0.025)PPS(0.975)PLEK 123.92 0.0034914 10205000 2164.7 1613.1 1677.2 1792.6 2151.3 4711.2 4721.3 9885.4 2232.1 2086.6 TRUE FALSE FALSE 1993.361711 1752.529176 1739.358507 1785.182696 2125.647153 3734.044014 4853.766971 12899.41295 1987.244214 2159.109195 0.923233394 0.811690849 0.805590802 0.826814457 0.984501922 1.729437317 2.248041453 5.974414349 0.920400052 1 11.07622049 -3.523848721 1.0694911 0.926494839 22.40329436 0.988360784 0.163886921 0.49788314 0.144237242 0.024992261 17.81505059 0.000299331 3.523848721 21.47679952 up SLPS(ph)SSQLKGSPQAISR ddPTM_HeLa_Curcumin_4h_R1 2 SLPSSSQLKGSPQAISR 17 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 0 S(0.027)LPS(0.467)S(0.467)S(0.035)QLKGS(0.003)PQAISR;S(0.003)LPS(0.427)S(0.427)S(0.139)QLKGS(0.005)PQAISR ; 70.134 0.008494 223254000 4832.6 3603.7 4762.8 5224.2 4371.6 5398 3361.2 1482.68 6058.7 4809.7 TRUE FALSE FALSE 4450.094611 3915.18777 4939.313558 5202.583645 4319.471525 4278.393952 3455.506226 1934.742307 5394.075768 4976.836717 0.894161264 0.786681982 0.99246044 1.045359521 0.867915057 0.859661306 0.694317781 0.388749404 1.083836195 1 12.28101334 -4.168676694 1.132211977 0.943641277 0.032596894 0.822819117 0.081807805 0.546764143 0.492348978 0.011390926 0.619384703 6.78E-05 4.168676694 -0.911044383 down DDS(ph)LDLSPQGR ddPTM_HeLa_Curcumin_4h_R1 1 DDSLDLSPQGR 11 0 Q14669;Q14669-2;Q14669-3;Q14669-4 Q14669 TRIP12 E3 ubiquitin-protein ligase TRIP12 1 0 DDS(0.5)LDLS(0.5)PQGR 107.39 0.0076776 9920900 3151.8 2967.6 2991.6 2880.4 3317 3713.8 2491.2 825.58 3061 3252.5 TRUE FALSE FALSE 2902.331704 3224.106121 3102.471328 2868.481668 3277.446941 2943.516017 2561.096367 1077.295541 2725.215958 3365.524133 0.862371384 0.95798039 0.921838978 0.852313504 0.973829577 0.874608501 0.760979944 0.320097405 0.809744887 1 11.71661549 -4.16849433 1.636708832 0.930146388 1.05E-12 0.900754835 0.058344466 0.256155965 0.542797821 0.00819563 0.402542749 6.78E-05 4.16849433 -0.930146388 down SRT(ph)GSESSQTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 S(0.007)RT(0.99)GS(0.003)ESSQTGTSTTSSR 186.58 1.42E-07 253760000 241.39 174.14 130.23 74.427 245.58 285.32 182.76 0 196.81 168.7 TRUE FALSE FALSE 222.2837268 189.1918856 135.0564384 74.11904079 242.6516189 226.1414158 187.8877537 0 175.2204354 174.5623124 1.273377533 1.083807169 0.773686121 0.424599329 1.390057312 1.295476742 1.076336301 0 1.003770132 1 7.447598308 -6.868343856 6.072396771 1.131313336 0.867400946 0.09122204 0.388785268 0.407503506 20.66407811 0.063137321 0.083395755 1.35E-07 6.868343856 -0.263912391 CIFMSETQSS(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 1 CIFMSETQSSPTK 13 0 B4DGW0;A0A087WUY7;O75928-2;O75928 B4DGW0 PIAS2 E3 SUMO-protein ligase PIAS2 1 0 CIFMSETQS(0.018)S(0.977)PT(0.005)K 208.08 6.31E-31 0 2280.8 1971.2 1961 2175.7 2479.9 2426.1 1951.6 780.29 2101.1 1989.4 TRUE FALSE FALSE 2100.272273 2141.581745 2033.676385 2166.69753 2450.328812 1922.899512 2006.356644 1018.196829 1870.614587 2058.531502 1.020276965 1.040344412 0.987925802 1.052545238 1.190328547 0.934112259 0.974654331 0.494622904 0.908713121 1 11.00739981 -4.166741138 2.411692651 1.02233876 0.282296682 0.821351005 0.072494076 0.210437614 1.164492465 0.008584867 0.354295833 6.81E-05 4.166741138 -0.740042078 down SRT(ph)PVQDHR ddPTM_HeLa_Curcumin_4h_R1 1 SRTPVQDHR 9 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(0.287)RT(0.713)PVQDHR 86.803 0.019323 18521000 3325.6 6479.8 2745.6 2498.6 1636.6 2180.6 1242.4 737.52 2318.8 2966.7 TRUE FALSE FALSE 3062.375251 7039.885039 2847.354351 2488.261455 1617.084614 1728.31898 1277.2584 962.3864529 2064.433441 3069.792604 0.997583761 2.293277086 0.927539648 0.810563375 0.526773246 0.563008386 0.41607319 0.313502108 0.672499321 1 11.58392547 -5.951483691 2.173636905 1.109475327 0.446554098 0.407116684 0.409567848 0.262930091 2.502301101 0.062410565 0.12324182 1.12E-06 5.951483691 -0.662921229 GIAPAS(ph)PMLGNASNPNKADIPER ddPTM_HeLa_Curcumin_4h_R1 1 GIAPASPMLGNASNPNKADIPER 23 1 H0YKP9;H0YIY6;J3KNR0;P27448-8;P27448-6;P27448-3;P27448-4;P27448-2;P27448;P27448-7 H0YKP9 MARK3 MAP/microtubule affinity-regulating kinase 3 1 0 GIAPAS(1)PMLGNASNPNKADIPER 99.343 0.00016722 41479000 2708.5 2078.9 2344.3 2821.5 2200.8 2991.6 2350.4 559.81 3450.1 2707.3 TRUE FALSE FALSE 2494.119367 2258.590853 2431.18182 2809.825381 2174.556897 2371.108438 2416.345898 730.493492 3071.632662 2801.378473 0.890318602 0.806242667 0.867851968 1.003015268 0.776245309 0.846407745 0.862556031 0.260762157 1.096471859 1 11.45192119 -4.166410662 2.459627006 0.918010622 6.49E-13 0.809048935 0.09397805 0.234275706 1.362588418 0.012097892 0.496387254 6.82E-05 4.166410662 -0.918010622 down SRTGS(ph)ESSQTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 2 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 S(0.003)RT(0.448)GS(0.548)ESSQTGTSTTSSR;SRT(0.015)GS(0.97)ES(0.015)SQTGTSTTSSR ; 163.92 8.67E-06 12622850 803.82 358.38 356.28 417.87 498.26 611.76 416.262 315.88 784.24 773.21 TRUE FALSE FALSE 740.1967988 389.3567703 369.4840502 416.1409647 492.3185749 484.87408 427.9411914 412.1903579 698.2108341 800.0789899 0.925154651 0.486647912 0.461809465 0.52012485 0.615337462 0.606032762 0.534873677 0.515187079 0.872677377 1 9.643998631 -7.302264525 5.612867143 0.966292753 0.536650856 0.914232356 0.055657672 0.034194666 2.864728719 0.009616217 0.011066567 4.99E-08 7.302264525 -0.429641898 SRTGSESSQTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 1 SRTGSESSQTGTSTTSSR 18 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 0 74.993 0.011183 252450 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 ADNPSPNLMPAS(ph)AQAQNAQR ddPTM_HeLa_Curcumin_4h_R1 1 ADNPSPNLMPASAQAQNAQR 20 0 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 0 ADNPS(0.304)PNLMPAS(0.696)AQAQNAQR 140.45 0.00013834 9908200 2568.5 2061.2 2145.1 2224.5 2198.6 2501.4 1891.4 531.02 3021 2000.2 TRUE FALSE FALSE 2365.200515 2239.360943 2224.599293 2215.295608 2172.383131 1982.581443 1944.467594 692.9255535 2689.603858 2069.706801 1.142770809 1.081970133 1.074837891 1.070342721 1.049609118 0.957904493 0.939489397 0.334794065 1.2995096 1 11.01521069 -4.166220446 1.859390601 1.065397889 2.22E-15 0.86817177 0.087253958 0.203497498 0.584570135 0.008648872 0.405950627 6.82E-05 4.166220446 -1.065397889 down SRTS(ph)VQTEDDQLIAGQSAR ddPTM_HeLa_Curcumin_4h_R1 3 SRTSVQTEDDQLIAGQSAR 19 1 G3XAM7;P35221-3;P35221;P35221-2;A0A0A0MTJ6;A0A0A0MRI5;P26232-4;P26232-6;P26232-3;P26232-2;P26232-5;P26232 G3XAM7 CTNNA1;CTNNA2 Catenin alpha-1;Catenin alpha-2 1 0 S(0.017)RT(0.249)S(0.734)VQTEDDQLIAGQSAR;S(0.005)RT(0.249)S(0.746)VQTEDDQLIAGQSAR;S(0.098)RT(0.057)S(0.844)VQTEDDQLIAGQSAR ;; 140.88 6.91E-05 132020000 2171.68 1858.87 2268.38 2169.14 2059.68 2539 2036.15 1147.76 2886.63 1830.12 TRUE FALSE FALSE 1999.789236 2019.54244 2352.448158 2160.164673 2035.119661 2012.38278 2093.278889 1497.70674 2569.973911 1893.716534 1.056012978 1.066443897 1.242238802 1.140701174 1.074669638 1.062663151 1.105381324 0.790882222 1.357105916 1 10.88700468 -4.255599124 24.53522048 1.061187405 0.790882068 0.328892895 0.11515432 315.8043272 1326659.487 0.010936344 0.12954609 5.55E-05 4.255599124 -0.270305337 SRTSPVTR ddPTM_HeLa_Curcumin_4h_R1 1 SRTSPVTR 8 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 0 96.665 0.014664 4997400 2751.5 3697.3 2073.2 1896.5 2146.8 2777.2 1512.6 2007.7 2029.7 2988 FALSE FALSE TRUE 2533.715872 4016.878137 2150.034616 1888.652786 2121.200812 2201.177415 1555.039485 2619.838488 1807.046988 3091.832778 0.81948671 1.299189971 0.695391624 0.610852178 0.686065827 0.71193288 0.502950708 0.847341585 0.58445819 1 11.59424658 -6.558943616 24.99999557 0.943878933 0.664230768 0.305060696 0.184172356 112.5702938 78032.781 0.022653767 0.032037316 2.76E-07 6.558943616 -0.279648164 SRVPVRPPQQYS(ph)DDEDDYEDDEEDDVQNTNSALR ddPTM_HeLa_Curcumin_4h_R1 1 SRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALR 34 2 Q92560;F8W6N3 Q92560 BAP1 Ubiquitin carboxyl-terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase 1 0 S(0.003)RVPVRPPQQY(0.073)S(0.549)DDEDDY(0.375)EDDEEDDVQNTNSALR 54.53 0.0003345 18904000 1151 696.17 791.63 852.05 883.05 983.66 852.41 586.64 1222.9 652.42 TRUE FALSE FALSE 1059.897135 756.3438327 820.9685042 848.5244429 872.5202055 779.6378279 876.3263305 765.5038354 1088.75093 675.0915464 1.570005048 1.120357434 1.216084705 1.256902782 1.292447239 1.154862377 1.298085178 1.133925968 1.612745612 1 9.398939343 -5.274739175 23.15228121 1.259823307 1.205870562 0.034608717 0.180829496 1496.653079 2605381.893 0.030487277 0.068625849 5.31E-06 5.274739175 -0.053952746 SRWDETPASQMGGS(ph)TPVLTPGK ddPTM_HeLa_Curcumin_4h_R1 2 SRWDETPASQMGGSTPVLTPGK 22 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 SRWDETPASQMGGS(0.462)T(0.462)PVLT(0.075)PGK;SRWDETPASQMGGS(0.606)T(0.392)PVLT(0.002)PGK ; 102.43 2.75E-05 34924000 4181.6 3214.4 3223.2 3633.6 4074.3 3974.6 2805.2 2519.8 3683.8 3334.7 TRUE FALSE FALSE 3850.621948 3492.238413 3342.654627 3618.565126 4025.716634 3150.223157 2883.906362 3288.07542 3279.696356 3450.580577 1.115934511 1.012072703 0.96872238 1.048682981 1.166678054 0.912954527 0.835774241 0.952904981 0.950476676 1 11.75262341 -5.102728889 7.762688027 1.051907843 0.889481357 0.454683967 0.067602259 0.155012767 10.37086737 0.009275497 0.023825478 7.89E-06 5.102728889 -0.162426486 SRWDETPASQMGGST(ph)PVLTPGK ddPTM_HeLa_Curcumin_4h_R1 1 SRWDETPASQMGGSTPVLTPGK 22 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 SRWDETPAS(0.007)QMGGS(0.138)T(0.85)PVLT(0.006)PGK 73.676 0.0010041 22354000 4250.4 3354.7 4244.2 4152.7 4139.6 4888.4 3046.7 2071.5 4178 3873.7 TRUE FALSE FALSE 3913.976355 3644.66532 4401.493786 4135.517228 4090.237974 3874.490736 3132.182202 2703.090814 3719.683853 4008.310787 0.97646529 0.909277128 1.098091944 1.031735673 1.02043933 0.966614353 0.781421993 0.674371564 0.927992876 1 11.96877866 -4.655957868 2.502014889 0.996437897 0.681082681 0.822720478 0.050224964 0.08049663 0.936648454 0.006517535 0.037539047 2.21E-05 4.655957868 -0.315355217 SRY(ph)RSSPTVYNSPT(ph)DK ddPTM_HeLa_Curcumin_4h_R1 1 SRYRSSPTVYNSPTDK 16 2 Q96SK2-3;Q96SK2-2;Q96SK2 Q96SK2-3 TMEM209 Transmembrane protein 209 2 0 S(0.016)RY(0.782)RS(0.067)S(0.081)PT(0.08)VY(0.049)NS(0.026)PT(0.9)DK 60.255 0.0093729 0 519.01 373.52 646.52 643.92 546.28 557.45 526.57 261.68 984.4 748.83 TRUE FALSE FALSE 477.9298108 405.8054044 670.4805999 641.2556297 539.7659678 441.8285862 541.344137 341.4650274 876.4137828 774.8517868 0.616801586 0.523720034 0.865301741 0.827584889 0.696605437 0.57021045 0.698642174 0.440684313 1.131072804 1 9.597776569 -9.274969362 0.838624058 1.016539631 0.660663891 0.597850195 0.131162379 0.457394949 0.535455483 0.107444214 0.024443096 5.31E-10 9.274969362 -0.355875741 SSS(ph)ESYTQSFQSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSESYTQSFQSR 13 0 Q9BTU6;E9PAM4 Q9BTU6 PI4K2A Phosphatidylinositol 4-kinase type 2-alpha 1 0 S(0.031)S(0.062)S(0.907)ES(0.001)YTQSFQSR 267.77 8.65E-47 28260000 1421.1 1084.3 1241.4 1366.2 1089.9 1576.5 744.94 462.57 1397.8 1366.8 TRUE FALSE FALSE 1308.618435 1178.02206 1287.407376 1360.547026 1076.903654 1249.516129 765.8410115 603.6054636 1244.464837 1414.296198 0.925278903 0.832938717 0.910281296 0.961995817 0.761441384 0.883489704 0.541499731 0.426788578 0.87991811 1 10.46586858 -4.165279944 0.677780094 0.954451383 1.00E-19 0.826490216 0.073883544 0.831406331 0.241887389 0.012005803 0.627456726 6.83E-05 4.165279944 -0.954451383 down SS(ph)GFISELPSEEGK ddPTM_HeLa_Curcumin_4h_R1 2 SSGFISELPSEEGK 14 0 Q5VZK9;Q5VZK9-2;A0A0U1RQQ1 Q5VZK9 LRRC16A Leucine-rich repeat-containing protein 16A 1 0 S(0.226)S(0.774)GFISELPSEEGK;S(0.207)S(0.793)GFISELPSEEGK ; 297.03 1.01E-77 18766200 8243.7 6489.2 6945.1 7278.8 7157.3 8214.9 6704.2 3373.8 7653 7391.2 TRUE FALSE FALSE 7591.202446 7050.097533 7202.491516 7248.682254 7071.953872 6511.037139 6892.301809 4402.456089 6813.485047 7648.04365 0.992567877 0.921817115 0.941742993 0.947782542 0.924674884 0.851333679 0.901184947 0.575631664 0.890879467 1 12.90087504 -3.632023199 0.708157558 0.98439928 1.61E-38 0.771839715 0.054685998 1.581047884 0.298038688 0.007521885 1.534297814 0.000233333 3.632023199 -0.98439928 SS(ph)GSPYGGGYGSGGGSGGYGSR ddPTM_HeLa_Curcumin_4h_R1 2 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 0 S(0.233)S(0.384)GS(0.384)PYGGGYGSGGGSGGYGSR;S(0.185)S(0.63)GS(0.185)PYGGGYGSGGGSGGYGSR ; 274.68 4.76E-73 128731600 3972.74 3056.68 3351.11 3106.4 3252.54 4832.3 3647.33 1877.66 3641.73 3077.05 TRUE FALSE FALSE 3658.293437 3320.885799 3475.305085 3093.54654 3213.755585 3830.026509 3749.664264 2450.14989 3242.24133 3183.977258 1.148969713 1.042999221 1.091498086 0.97159819 1.009352556 1.202906365 1.177666786 0.769524934 1.018299148 1 11.63661432 SS(ph)ITEPEGPNGPNIQK ddPTM_HeLa_Curcumin_4h_R1 1 SSITEPEGPNGPNIQK 16 0 Q13625-2;Q13625;Q13625-3 Q13625-2 TP53BP2 Apoptosis-stimulating of p53 protein 2 1 0 S(0.016)S(0.983)ITEPEGPNGPNIQK 249.41 1.16E-31 26842000 1906.7 1480.4 2145.2 1684.8 2103.6 2400.9 1387.1 508.21 1514.7 1512.2 TRUE FALSE FALSE 1755.782683 1608.359179 2224.702999 1677.828744 2078.515944 1902.926276 1426.018293 663.1608895 1348.5412 1564.748837 1.122085948 1.027870506 1.421763638 1.072267129 1.328338385 1.216122505 0.911340056 0.423812994 0.86182598 1 10.61171539 -4.332016864 2.87256302 1.111024187 0.355880425 0.654359475 0.155256929 0.150775557 1.86849875 0.020093838 0.241479026 4.66E-05 4.332016864 -0.755143762 SS(ph)KASLGS(ph)LEGEAEAEASSPK ddPTM_HeLa_Curcumin_4h_R1 1 SSKASLGSLEGEAEAEASSPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 S(0.435)S(0.492)KAS(0.213)LGS(0.86)LEGEAEAEASSPK 63.893 0.0050724 78219000 4608.6 3401.4 3669 3499.4 3109.8 3871.9 3564.3 3745.9 4922.9 3191.8 TRUE FALSE FALSE 4243.824447 3695.40186 3804.976368 3484.92041 3072.717666 3068.824295 3664.304665 4888.007666 4382.870186 3302.714812 1.284950318 1.118898261 1.152075363 1.055168432 0.930361185 0.929182345 1.109482615 1.479996895 1.327050755 1 11.68943668 -6.270333786 22.95664187 1.137748291 1.082311144 0.017642162 0.168287027 863.7024941 2229239.089 0.027274915 0.042118825 5.37E-07 6.270333786 -0.055437148 SS(ph)LEGPTILDIEK ddPTM_HeLa_Curcumin_4h_R1 1 SSLEGPTILDIEK 13 0 A0A0G2JR96;A0A0G2JQT1;Q7L576-2;Q7L576 A0A0G2JR96 CYFIP1 Cytoplasmic FMR1-interacting protein 1 1 0 S(0.216)S(0.737)LEGPT(0.047)ILDIEK 168 0.00018754 1988500 1241.1 1022 1071.9 1108.2 1210.7 1343.7 875.21 1127.2 1196.3 1203 TRUE FALSE FALSE 1142.865625 1110.337126 1111.625557 1103.614562 1196.263193 1065.001473 899.7660371 1470.878091 1065.068883 1244.80416 0.918108777 0.891977358 0.893012405 0.886576859 0.961005137 0.85555745 0.722817344 1.181614054 0.855611603 1 10.28170307 -8.797664946 0.68858799 1.000786133 0.903645345 0 0.116518169 1.285164963 1.151518235 0.066209219 0.022324534 1.59E-09 8.797664946 -0.097140788 SS(ph)LETLEDIEENAPLR ddPTM_HeLa_Curcumin_4h_R1 1 SSLETLEDIEENAPLR 16 0 V9GYB4;Q8TDN4-2;Q8TDN4 V9GYB4 CABLES1 CDK5 and ABL1 enzyme substrate 1 1 0 S(0.035)S(0.965)LETLEDIEENAPLR 148.33 0.00035777 4215200 977.66 923.86 1011.7 980.94 961.36 1247.6 990.75 494.45 1072.8 878.79 TRUE FALSE FALSE 900.2771794 1003.714342 1049.194492 976.8811302 949.8964099 988.8336967 1018.547779 645.2055288 955.116524 909.3278871 0.990046816 1.103798043 1.15381317 1.074289202 1.044613745 1.087433599 1.120110571 0.709541122 1.050354374 1 9.828656788 -4.251810722 24.54732152 1.033949424 0.709540897 0.752459428 0.058839281 493.6927214 1258587.774 0.009955413 0.170834659 5.60E-05 4.251810722 -0.324408527 SS(ph)LETLEDIEENAPLRR ddPTM_HeLa_Curcumin_4h_R1 1 SSLETLEDIEENAPLRR 17 1 V9GYB4;Q8TDN4-2;Q8TDN4 V9GYB4 CABLES1 CDK5 and ABL1 enzyme substrate 1 1 0 S(0.439)S(0.545)LET(0.017)LEDIEENAPLRR 116.13 0.00037776 3083700 312.45 369.24 314.09 389.65 354.92 457.08 393.05 228.36 336.46 319.19 TRUE FALSE FALSE 287.7192528 401.1554603 325.7304517 388.0377315 350.6878108 362.2764556 404.0779252 297.9859128 299.5511798 330.2818287 0.871132553 1.214585319 0.986219717 1.174868545 1.061783545 1.096870685 1.223433716 0.902217097 0.906956283 1 8.367553788 -7.272724349 24.98533374 0.939145928 1.097042774 0.378465398 0.098333634 559.2104958 1238110.019 0.016103315 0.018505471 5.34E-08 7.272724349 0.157896846 SS(ph)LSGDEEDELFK ddPTM_HeLa_Curcumin_4h_R1 1 SSLSGDEEDELFK 13 0 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 0 S(0.259)S(0.74)LSGDEEDELFK 110.51 0.0039613 0 1165.6 1001.7 1178.2 1300.1 1012.6 1088.6 1171.8 1186.2 1112.3 1103.2 TRUE FALSE FALSE 1073.34153 1088.282485 1221.865128 1294.720531 1000.525406 862.8120889 1204.677554 1547.866919 990.2834728 1141.536118 0.940260683 0.953349147 1.070369224 1.134191473 0.876472843 0.755834244 1.055312693 1.355950894 0.86750078 1 10.15676079 -6.781094819 24.59405204 0.96961849 1.02573662 0.078173587 0.152077397 687.33689 860033.7113 0.024640842 0.032412214 1.66E-07 6.781094819 0.05611813 SS(ph)LYFPR ddPTM_HeLa_Curcumin_4h_R1 1 SSLYFPR 7 0 B8ZZW8;E7ENZ2;E9PG19;O94868-2;O94868 B8ZZW8 FCHSD2 F-BAR and double SH3 domains protein 2 1 0 S(0.224)S(0.776)LYFPR 112.41 0.015343 2487700 1251.1 1098.5 1275 1229.5 1277 1655.3 1490.8 679.92 1481.9 1232.1 TRUE FALSE FALSE 1152.074115 1193.449445 1322.252622 1224.412655 1261.772609 1311.972121 1532.627836 887.224478 1319.339278 1274.915383 0.903647513 0.936100906 1.03712971 0.960387388 0.989691258 1.029066037 1.202140829 0.69590852 1.034844582 1 10.31618578 -6.783288658 24.88118494 0.951848948 0.996557141 0 0.121856795 707.3339453 805483.76 0.017986271 0.023650138 1.65E-07 6.783288658 0.044708193 SS(ph)LYGIAK ddPTM_HeLa_Curcumin_4h_R1 1 SSLYGIAK 8 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 0 S(0.159)S(0.841)LYGIAK 109.29 0.011503 27172000 3553.7 2352.8 2553.8 2643.3 2701.2 4554.8 4690.3 1801 3225.8 2281.9 TRUE FALSE FALSE 3272.420895 2556.165548 2648.446075 2632.362725 2668.989954 3610.083137 4821.897195 2350.116609 2871.937811 2361.195855 1.385916754 1.082572436 1.12165455 1.114843023 1.130355175 1.528921512 2.042141987 0.995307782 1.216306476 1 11.205302 -5.227791551 6.197324854 1.165552128 1.577875867 0.302014688 0.254499559 0.171155156 20.71710738 0.035507616 0.090152916 5.92E-06 5.227791551 0.412323739 MS(ph)ADMSEIEAR ddPTM_HeLa_Curcumin_4h_R1 3 MSADMSEIEAR 11 0 Q9UG54;O43318-4;O43318-3;O43318-2;O43318 Q9UG54 DKFZp586F0420;MAP3K7 Mitogen-activated protein kinase kinase kinase 7 1 0 MS(1)ADMSEIEAR;MS(1)ADMSEIEAR;MS(0.918)ADMS(0.082)EIEAR ;; 218.02 4.46E-11 117326000 8593.7 7027.3 7574 7676.6 7898.2 9101.4 6346.2 2143.26 9077.1 8184 TRUE FALSE FALSE 7913.499577 7634.708499 7854.699103 7644.836263 7804.019123 7213.667046 6524.257292 2796.730108 8081.36484 8468.393391 0.934474724 0.901553358 0.927531202 0.902749307 0.921546598 0.851834193 0.770424447 0.3302551 0.954297287 1 13.04787257 -4.165093822 1.338881156 0.951800381 1.27E-20 0.961180414 0.0359838 0.256925194 0.33755895 0.006575123 0.351197169 6.84E-05 4.165093822 -0.951800381 down SS(ph)PAAKPGS(ph)TPSRPSSAK ddPTM_HeLa_Curcumin_4h_R1 1 SSPAAKPGSTPSRPSSAK 18 2 Q15555-2;Q15555;K7EL66;K7ERD8;Q15555-4;Q15555-5;Q15555-3 Q15555-2 MAPRE2 Microtubule-associated protein RP/EB family member 2 2 0 S(0.449)S(0.551)PAAKPGS(0.602)T(0.169)PS(0.225)RPS(0.002)S(0.001)AK 80.41 0.0046156 4575900 2276.1 2140.6 2193.4 2363.2 2648 3337.6 3169.2 1537.4 2426.8 1764.4 TRUE FALSE FALSE 2095.944283 2325.623926 2274.689334 2353.421705 2616.424329 2645.344137 3258.119223 2006.146183 2160.586112 1825.712769 1.148014255 1.27381698 1.245918511 1.289042693 1.433097459 1.448937743 1.784573827 1.098829026 1.183420606 1 10.83424409 -6.804169209 0.489990001 1.020547849 1.494931792 0.366277626 0.167875677 0.493874342 0.262882113 0.051185324 0.090246963 1.57E-07 6.804169209 0.474383943 SS(ph)PAFGDR ddPTM_HeLa_Curcumin_4h_R1 1 SSPAFGDR 8 0 P13716;P13716-2 P13716 ALAD Delta-aminolevulinic acid dehydratase 1 0 S(0.224)S(0.776)PAFGDR 91.265 0.020166 8029800 1790.7 1852.6 2009.7 1857.1 1728.5 1806.4 1595.3 1530.8 1942.3 1720.9 TRUE FALSE FALSE 1648.964205 2012.730489 2084.18125 1849.415812 1707.888766 1431.732278 1640.059824 1997.533873 1729.234549 1780.701147 0.926019623 1.130302237 1.170427308 1.038588544 0.959110275 0.804027268 0.921019132 1.121768173 0.971097566 1 10.7982297 -4.244441052 23.05867151 0.980687221 1.121768509 0.125089309 0.100213072 1879.443426 2549390.587 0.014966055 0.506846159 5.70E-05 4.244441052 0.141081288 SS(ph)PELTR ddPTM_HeLa_Curcumin_4h_R1 2 SSPELTR 7 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.202)S(0.798)PELTR;S(0.226)S(0.774)PELTR ; 129.42 0.0074215 178027000 5239.2 4540.4 5862.3 4821 5813 5498.1 3160.1 1407.01 4424.7 3838.1 TRUE FALSE FALSE 4824.511792 4932.851944 6079.561995 4801.051979 5743.683772 4357.732084 3248.763901 1836.000872 3939.32148 3971.473689 1.214791327 1.242070911 1.530807572 1.208884247 1.446234879 1.097258203 0.818024783 0.462297126 0.991904212 1 11.95545873 -4.518825983 2.201373969 1.1779505 0.440791487 0.6820739 0.165212948 0.207621432 1.622980051 0.02654951 0.240404726 3.03E-05 4.518825983 -0.737159014 SS(ph)PGGQDEGGFMAQGK ddPTM_HeLa_Curcumin_4h_R1 2 SSPGGQDEGGFMAQGK 16 0 A0A1B0GTU4;F5GZ78;P49023;A0A1B0GV30 A0A1B0GTU4 PXN Paxillin 1 0 S(0.036)S(0.964)PGGQDEGGFMAQGK;S(0.058)S(0.942)PGGQDEGGFMAQGK ; 105.19 0.0023223 160908000 11994.2 10035.2 11707.1 10427.6 11232 9125.9 6716.6 5488.1 10718 9846.7 TRUE FALSE FALSE 11044.84641 10902.59797 12140.97542 10384.45335 11098.06574 7233.08547 6905.049719 7161.396426 9542.262215 10188.87209 1.084010704 1.070049548 1.191591701 1.019195575 1.089233983 0.709900508 0.677705016 0.702864494 0.936537639 1 13.31470673 -5.256376636 23.14128971 1.055831581 0.694911408 0.871733546 0.063100824 33.57914501 153484.3404 0.008153649 0.020060862 5.54E-06 5.256376636 -0.360920172 SS(ph)PKEELHPAAPSQLAPSFSSSSSSSSGPR ddPTM_HeLa_Curcumin_4h_R1 1 SSPKEELHPAAPSQLAPSFSSSSSSSSGPR 30 1 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 S(0.221)S(0.777)PKEELHPAAPS(0.002)QLAPSFSSSSSSSSGPR 59.555 0.00073185 7868100 1104.4 808.52 869.55 1048.7 1090.2 1323.7 853.02 784.23 1423.7 1095.1 TRUE FALSE FALSE 1016.985575 878.4048661 901.7762879 1044.360757 1077.200077 1049.149699 876.9534454 1023.338117 1267.523672 1133.154643 0.897481717 0.775185339 0.795810433 0.921640099 0.950620538 0.925866302 0.773904471 0.903087785 1.118579604 1 10.14612905 -8.529762769 0.930836794 0.988965929 0.867077238 0.462468957 0.074567026 0.402779874 0.714354331 0.025176644 0.013634776 2.95E-09 8.529762769 -0.121888691 SS(ph)PKSEIEVISEPPEEK ddPTM_HeLa_Curcumin_4h_R1 1 SSPKSEIEVISEPPEEK 17 1 B7ZM87;O75044;A0A075B7E9;A0A075B7E6;Q5VZB4 B7ZM87 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 1 0 S(0.448)S(0.542)PKS(0.01)EIEVISEPPEEK 67.579 0.0097358 22988000 4097.1 3509.9 3898.1 4061.6 3863 4035.5 3826.3 3817.6 4038.8 3466.9 TRUE FALSE FALSE 3772.810212 3813.280116 4042.567015 4044.794175 3816.936248 3198.491811 3933.65568 4981.568666 3595.753745 3587.374517 1.0516912 1.062972405 1.126887365 1.127508198 1.063991571 0.891596848 1.096527742 1.388639141 1.002335755 1 11.80871265 -4.287937281 3.9701624 1.036930797 1.412380757 0.717342124 0.06495064 0.086726388 2.743501822 0.00926323 0.088882974 5.15E-05 4.287937281 0.375449959 SS(ph)PNPFVGS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 1 SSPNPFVGSPPK 12 0 P98082-3;P98082 P98082-3 DAB2 Disabled homolog 2 2 0 S(0.399)S(0.601)PNPFVGS(1)PPK 145.94 0.0019595 28341000 3557 3426.1 3580 4040.2 3700.2 4091.5 2995.7 3179.7 3757.6 2776.5 TRUE FALSE FALSE 3275.459697 3722.236818 3712.677949 4023.482723 3656.077532 3242.876779 3079.751279 4149.175892 3345.400681 2872.983168 1.14009011 1.295599939 1.292272781 1.40045468 1.272571859 1.128748966 1.07196983 1.444204734 1.164434487 1 11.48833383 -7.845969236 1.07568398 1.03282339 1.264073191 0.281964132 0.115141414 0.292853989 0.713827062 0.027983145 0.02468068 1.43E-08 7.845969236 0.2312498 SS(ph)PPLRTPDVLESSGPAVR ddPTM_HeLa_Curcumin_4h_R1 1 SSPPLRTPDVLESSGPAVR 19 1 A0A0A6YYC0;E9PJN1;O75676-2;O75676 A0A0A6YYC0 RPS6KA4 Ribosomal protein S6 kinase;Ribosomal protein S6 kinase alpha-4 1 0 S(0.477)S(0.511)PPLRT(0.013)PDVLESSGPAVR 68.705 0.0048679 41351000 963.45 558.14 785.59 883.82 712.65 1224.9 758.84 319.2 875.07 837.65 TRUE FALSE FALSE 887.1919159 606.3831346 814.7046565 880.162987 704.1521142 970.8419325 780.1310081 416.5226106 779.0770103 866.7582752 1.023574786 0.699598899 0.93994448 1.015465341 0.812397337 1.120083835 0.900056025 0.480552217 0.898840003 1 9.759485895 -4.280959305 3.829546506 0.976869445 0.440376327 0.560525822 0.116948046 0.112735547 3.210199528 0.015618927 0.163924155 5.24E-05 4.280959305 -0.536493118 SS(ph)PQLDPLR ddPTM_HeLa_Curcumin_4h_R1 1 SSPQLDPLR 9 0 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 0 S(0.251)S(0.749)PQLDPLR 89.266 0.020391 63431000 2866.2 2514.3 3010.8 2806.7 2963.2 3699.3 3666.3 1393.9 2902.1 2335.1 TRUE FALSE FALSE 2639.337246 2731.624888 3122.382897 2795.086619 2927.865775 2932.02348 3769.166511 1818.893693 2583.746891 2416.244551 1.092330346 1.130525007 1.292246224 1.156789621 1.211742319 1.213463049 1.559927578 0.752777153 1.069323422 1 11.23855076 -7.49427648 0.916591288 1.0231026 1.215368853 0.095682301 0.186982407 0.628737419 1.083339897 0.04130189 0.043213825 3.20E-08 7.49427648 0.192266252 SS(ph)PQLDPLRK ddPTM_HeLa_Curcumin_4h_R1 1 SSPQLDPLRK 10 1 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 1 0 S(0.182)S(0.818)PQLDPLRK 82.774 0.013311 161430000 6042.8 5171.6 5096.5 5299.4 7363.6 5479.1 4943.2 1384.4 4940.1 4014.2 TRUE FALSE FALSE 5564.506004 5618.61006 5285.380773 5277.472487 7275.793879 4342.672898 5081.892888 1806.497187 4398.18339 4153.693151 1.339652642 1.352678172 1.272453352 1.270549435 1.751644528 1.0454968 1.223463723 0.434913491 1.058860929 1 12.02017893 -4.261242325 8.732607471 1.226061456 0.430770469 0.587603184 0.205175358 0.05227856 68.54544885 0.030632391 0.241156898 5.48E-05 4.261242325 -0.795290987 SS(ph)PSPALEQPFR ddPTM_HeLa_Curcumin_4h_R1 1 SSPSPALEQPFR 12 0 Q9UMZ2-6;Q9UMZ2-9;Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2 Q9UMZ2-6 SYNRG Synergin gamma 1 0 S(0.224)S(0.747)PS(0.029)PALEQPFR 112.02 0.004978 18583000 896.48 789.48 919.91 812.12 944.33 923.32 688.78 608.87 694.68 651.51 TRUE FALSE FALSE 825.522662 857.7191333 954.0026738 808.7596626 933.0694815 731.813024 708.105313 794.5116601 618.475342 674.149924 1.224538686 1.272297308 1.415119456 1.199673298 1.384068214 1.085534535 1.050367712 1.17853853 0.917415133 1 9.396925657 -9.000866606 0.882391791 1.004777465 1.22611856 0.458060776 0.112700827 0.501825784 0.732455294 0.067609859 0.02271665 9.98E-10 9.000866606 0.221341095 SS(ph)PSTGSLDSGNESK ddPTM_HeLa_Curcumin_4h_R1 1 SSPSTGSLDSGNESK 15 0 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2" 1 0 S(0.134)S(0.511)PS(0.079)T(0.05)GS(0.225)LDSGNESK 170.74 0.00016252 22043000 1878.3 1783.3 2225.9 1597.1 2000.8 2035.2 1262.3 659.61 1934.7 1384.1 TRUE FALSE FALSE 1729.630573 1937.440506 2308.393812 1590.491623 1976.941767 1613.076579 1297.716741 860.7220525 1722.46825 1432.197372 1.207676125 1.352774795 1.6117847 1.110525445 1.380355673 1.126294888 0.906101887 0.600980053 1.202675193 1 10.48401461 -4.476709977 2.144520698 1.178561181 0.565813058 0.57299682 0.172771395 0.310166361 2.167167402 0.028838985 0.304524325 3.34E-05 4.476709977 -0.612748123 S(ph)YDSSMESR ddPTM_HeLa_Curcumin_4h_R1 2 SYDSSMESR 9 0 Q9HCG8;B7WP74 Q9HCG8 CWC22 Pre-mRNA-splicing factor CWC22 homolog 1 0 S(0.992)YDS(0.008)SMESR;S(0.871)YDS(0.128)S(0.002)MESR ; 153.1 0.0014487 126540000 2806.8 2462.7 2311.6 2194.4 2172.67 2510.9 1634.16 746.66 2188.6 2221.4 TRUE FALSE FALSE 2584.638818 2675.564814 2397.269929 2185.320154 2146.762329 1990.111036 1680.010131 974.3131968 1948.516056 2298.593485 1.124443637 1.164000869 1.042929054 0.95072059 0.93394606 0.865795126 0.730886145 0.423873644 0.847699286 1 11.16653563 -4.164736394 0.717248095 1.065200822 3.37E-17 0.815651125 0.087225948 0.683196062 0.224027307 0.011386441 0.60585697 6.84E-05 4.164736394 -1.065200822 down SS(ph)PVNNHHS(ph)PGQTPTLGQPEAR ddPTM_HeLa_Curcumin_4h_R1 1 SSPVNNHHSPGQTPTLGQPEAR 22 0 H0Y2V6;Q5SW79;Q5SW79-3;Q5SW79-2;E7EWM2;E7EMW0;Q96L14 H0Y2V6 CEP170;CEP170P1 Centrosomal protein of 170 kDa;Cep170-like protein 2 0 S(0.452)S(0.549)PVNNHHS(0.989)PGQT(0.009)PT(0.002)LGQPEAR 91.809 0.00062315 17794000 618.89 680.23 599.72 635.85 717.86 843.56 561.29 403.86 755.07 567.96 TRUE FALSE FALSE 569.9042035 739.0260502 621.9461508 633.2190212 709.2999883 668.5961471 577.0382868 526.9950549 672.2407101 587.6965677 0.969725254 1.257495944 1.058277664 1.077459111 1.206915315 1.137655355 0.981864313 0.896712834 1.143856791 1 9.198927662 SS(ph)PVVNDGVVR ddPTM_HeLa_Curcumin_4h_R1 1 SSPVVNDGVVR 11 0 H0YAM1;H0Y8R1;F5H5I6;H0YAK1;Q12849-5;Q12849 H0YAM1 GRSF1 G-rich sequence factor 1 1 0 S(0.032)S(0.968)PVVNDGVVR 118.76 0.0043603 13303000 610.52 736.43 619.15 802.98 582.71 770.59 708.66 741.99 695.41 761.46 TRUE FALSE FALSE 562.1966978 800.0837277 642.0962437 799.6574815 575.7615638 610.7609477 728.5430923 968.2193353 619.1252628 787.9206783 0.71351941 1.015436896 0.814924981 1.01489592 0.73073544 0.775155373 0.924640148 1.228828437 0.785771055 1 9.621906588 -4.282663583 3.701642103 0.865184812 1.260277947 0.502993107 0.110248405 0.181381209 4.621801099 0.01748379 0.18936465 5.22E-05 4.282663583 0.395093135 SS(ph)RGQEEISGALPVAS(ph)PASSR ddPTM_HeLa_Curcumin_4h_R1 1 SSRGQEEISGALPVASPASSR 21 1 Q9UBK8;Q9UBK8-1;H0Y9D5;H0Y8S9 Q9UBK8 MTRR Methionine synthase reductase 2 0 S(0.47)S(0.53)RGQEEISGALPVAS(0.923)PAS(0.061)S(0.016)R 80.93 0.00081888 20728000 2212 1776.9 1873.9 2214.8 2097.1 3578.6 2656 1264.5 2398.2 1820.6 TRUE FALSE FALSE 2036.917866 1930.487318 1943.348382 2205.635744 2072.093452 2836.358021 2730.520212 1650.040229 2135.12346 1883.865714 1.081243663 1.024747838 1.031574792 1.170803061 1.099915687 1.505605203 1.449424017 0.875879961 1.13337349 1 10.87948042 -5.741340218 1.97889705 1.040038166 1.286416927 0.201725361 0.167100217 0.293721687 2.340205709 0.023750192 0.053407752 1.81E-06 5.741340218 0.246378761 SS(ph)S(ph)MLS(ph)FS(ph)NTDK ddPTM_HeLa_Curcumin_4h_R1 1 SSSMLSFSNTDK 12 0 Q8IWZ5 Q8IWZ5 TRIM42 Tripartite motif-containing protein 42 4 0 S(0.231)S(0.88)S(0.871)MLS(0.973)FS(0.914)NT(0.131)DK 49.482 0.0096924 0 609.16 548.32 704.25 731.8 622.34 656.9 712.09 605.45 663.22 666.34 TRUE FALSE FALSE 560.9443432 595.7143375 730.3501245 728.7720055 614.919002 520.6515352 732.0693289 790.0489179 590.4664253 689.4952654 0.813557933 0.863986118 1.059253284 1.056964481 0.891839339 0.755119812 1.061746709 1.14583661 0.85637488 1 9.429396835 -6.776290919 24.94528136 0.905900032 0.985361425 0.178816686 0.112037043 471.2609385 791548.1506 0.020596316 0.027130905 1.67E-07 6.776290919 0.079461393 SS(ph)S(ph)PAPADIAQTVQEDLR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPAPADIAQTVQEDLR 18 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 2 0 S(0.579)S(0.667)S(0.754)PAPADIAQTVQEDLR 82.877 0.0044467 0 286.97 287.92 334.58 238.36 496.02 304.54 247.23 352.46 180.36 212.54 TRUE FALSE FALSE 264.2560217 312.8065219 346.9798291 237.3737295 490.1052855 241.3749711 254.1666084 459.9234315 160.5749592 219.9257492 1.201569269 1.422327868 1.577713526 1.079335777 2.228503426 1.09752938 1.155692816 2.091266863 0.730132601 1 7.780872716 -7.444950623 0.646314757 1.02731998 1.548477837 0.312592686 0.378232059 0.657091908 0.605718835 0.108444657 0.112720892 3.59E-08 7.444950623 0.521157857 SS(ph)SDSWEPTSAGSK ddPTM_HeLa_Curcumin_4h_R1 1 SSSDSWEPTSAGSK 14 0 A0A3B3IRS8;B1AL16;Q8IX21;Q8IX21-2 A0A3B3IRS8 FAM178A Protein FAM178A 1 0 S(0.017)S(0.628)S(0.354)DS(0.001)WEPTSAGSK 201.3 6.47E-09 7896200 2753.2 2637 2501.5 2975.5 2848.1 3074 2428.7 1784 2991.1 2501.8 TRUE FALSE FALSE 2535.281315 2864.93053 2594.207791 2963.188169 2814.138268 2436.417749 2496.842785 2327.933387 2662.983813 2588.737364 0.979350532 1.1066903 1.002113164 1.144646116 1.087069823 0.941160653 0.964502162 0.89925437 1.028680565 1 11.33803289 -5.124146346 10.26539196 1.017362818 0.937110909 0.378810973 0.057732873 0.445416971 34.98465575 0.009126193 0.023305569 7.51E-06 5.124146346 -0.080251909 SS(ph)SRS(ph)DLS(ph)VIQRNPKR ddPTM_HeLa_Curcumin_4h_R1 1 SSSRSDLSVIQRNPKR 16 3 Q9BVJ6-3;Q9BVJ6;Q9BVJ6-2 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 3 0 S(0.142)S(0.668)S(0.194)RS(0.997)DLS(1)VIQRNPKR 56.304 0.018771 17132000 6261.6 4777.7 5215.6 6950.5 5383.7 6307.6 4640 6913 5795.4 5683.2 TRUE FALSE FALSE 5765.987753 5190.663099 5408.894724 6921.740673 5319.502894 4999.332659 4770.185912 9020.741876 5159.659119 5880.690777 0.980494974 0.882662139 0.919772001 1.177028505 0.904571095 0.850126771 0.811160813 1.533959567 0.877389973 1 12.52176992 -4.251609611 24.92579739 0.9669839 1.533959885 0.750326415 0.102268937 497.9083122 1262543.039 0.013612587 0.241946047 5.60E-05 4.251609611 0.566975985 SS(ph)SSERPEPQQK ddPTM_HeLa_Curcumin_4h_R1 1 SSSSERPEPQQK 12 1 P78362;C9J2M4 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 0 S(0.233)S(0.48)S(0.274)S(0.013)ERPEPQQK 74.649 0.013587 28874000 2982.6 3312.4 2995.7 2850.9 2978.1 4266.7 2915.3 2282.5 3622.3 3226.1 TRUE FALSE FALSE 2746.524063 3598.709096 3106.723277 2839.103731 2942.588103 3381.738324 2997.095472 2978.423743 3224.942753 3338.206735 0.822754335 1.078036617 0.930656345 0.850487689 0.881487678 1.013040412 0.897816016 0.892222675 0.966070411 1 11.70485759 SS(ph)TDSLPGPISR ddPTM_HeLa_Curcumin_4h_R1 1 SSTDSLPGPISR 12 0 Q9HCD5 Q9HCD5 NCOA5 Nuclear receptor coactivator 5 1 0 S(0.075)S(0.785)T(0.129)DS(0.011)LPGPISR 163.71 0.00012549 14751000 2363.9 2216.6 2114.2 1775.9 2302.1 2260.1 1350 968.23 2319.3 2310.6 TRUE FALSE FALSE 2176.794821 2408.193027 2192.554112 1768.551796 2274.648961 1791.329783 1387.877367 1263.43887 2064.878593 2390.893178 0.910452563 1.007235726 0.917043945 0.739703393 0.951380422 0.749230371 0.580484891 0.528438025 0.863643182 1 11.22333396 -3.921013415 0.466646243 0.967559206 1.17E-18 0.777357044 0.075765011 1.673919461 0.19566828 0.015194609 0.953721945 0.000119946 3.921013415 -0.967559206 SS(ph)TPLPTISSSAENTR ddPTM_HeLa_Curcumin_4h_R1 1 SSTPLPTISSSAENTR 16 0 G5E972;P42167;H0YJH7;P42167-3;P42167-2;P42166 G5E972;P42166 TMPO "Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin" 1 0 S(0.215)S(0.78)T(0.006)PLPTISSSAENTR 140.49 0.00039417 9553100 837.21 529.71 739.42 903.88 904.49 1254.9 920.68 310.15 870.02 483.7 TRUE FALSE FALSE 770.9439451 575.4957721 766.8235557 900.1399841 893.7045475 994.6195944 946.5118029 404.7133072 774.5809827 500.508539 1.540321263 1.149822085 1.532088857 1.798450803 1.785593008 1.987218033 1.891100209 0.808604201 1.547587948 1 8.967250872 -6.583211399 4.428439237 1.25507339 1.691861713 0.172614461 0.342329554 0.223799447 8.970000107 0.055767631 0.08036474 2.61E-07 6.583211399 0.436788322 SS(ph)TPLSEAK ddPTM_HeLa_Curcumin_4h_R1 1 SSTPLSEAK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(0.016)S(0.492)T(0.492)PLSEAK 169.76 0.00094529 66693000 13049 10702 10917 12008 12381 20513 20205 6762.9 11985 7965.8 TRUE FALSE FALSE 12016.15788 11627.03319 11321.59362 11958.31408 12233.36466 16258.37257 20771.89792 8824.877077 10670.27548 8242.610957 1.45780966 1.410600749 1.373544582 1.450792005 1.484161357 1.97247846 2.520062882 1.070640981 1.294526157 1 13.00888569 -7.20594354 0.147800264 0.638695649 2.249461833 0.234471126 0.367960802 3.808130694 0.492628857 2.286567693 2.540568886 6.22E-08 7.20594354 1.610766184 LS(ph)S(ph)LRASTSKSESSQK ddPTM_HeLa_Curcumin_4h_R1 1 LSSLRASTSKSESSQK 16 2 P62753;A2A3R5 P62753 RPS6 40S ribosomal protein S6 2 0 LS(0.966)S(0.956)LRAS(0.078)TSKSESSQK 79.337 0.0096335 47664000 8288.3 5898.5 7587.2 7554 5756.2 8941.1 5790.6 1923.1 8820.5 7253.1 TRUE FALSE FALSE 7632.272309 6408.340057 7868.388306 7522.74355 5687.561074 7086.615073 5953.068651 2509.444337 7852.913218 7505.144685 1.016938731 0.853859629 1.048399283 1.002344907 0.757821643 0.944234305 0.793198386 0.334363219 1.046337352 1 12.87366417 -4.164256905 1.289050837 0.985617914 2.33E-35 0.819315123 0.088056009 0.496200683 0.596613621 0.012587308 0.680688882 6.85E-05 4.164256905 -0.985617914 down SS(ph)TVASLDTDSTK ddPTM_HeLa_Curcumin_4h_R1 1 SSTVASLDTDSTK 13 0 C9IZZ8;C9J6Y2;C9J0J6;C9JZ07;G3V1A3;C9J5T5;C9JBU8;A8MPU2;O14713-2;O14713 C9IZZ8 ITGB1BP1 Integrin beta-1-binding protein 1 1 0 S(0.015)S(0.595)T(0.327)VAS(0.061)LDT(0.001)DS(0.001)TK 190.34 8.12E-06 19544000 3388.2 2750 2974.5 2690.1 2669.2 3102.7 2309 1687.6 3556.7 2318.4 TRUE FALSE FALSE 3120.020395 2987.697746 3084.737587 2678.969079 2637.371533 2459.165045 2373.784326 2202.141471 3166.538908 2398.964227 1.300569787 1.245411546 1.28586227 1.116719061 1.099379267 1.025094504 0.989503844 0.91795511 1.31996087 1 11.22819593 -5.146790523 1.332614246 1.164126159 0.938031616 0.51867682 0.097255572 0.469282939 1.472747229 0.019208362 0.09114735 7.13E-06 5.146790523 -0.226094543 SS(ph)VDLEESSTK ddPTM_HeLa_Curcumin_4h_R1 1 SSVDLEESSTK 11 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 S(0.151)S(0.849)VDLEESSTK 127.52 0.0032162 80878000 5386 4578.2 5003.9 5169.8 5093.8 3332.2 4129.4 4967.2 4745 4695 TRUE FALSE FALSE 4959.692417 4973.919208 5189.348936 5148.408737 5033.059762 2641.064158 4245.25985 6481.676414 4224.485371 4858.150901 1.020901268 1.023829706 1.068173682 1.059746567 1.036003176 0.543635678 0.873842731 1.334185896 0.86956652 1 12.24619159 SSADKIGEVS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 SSADKIGEVSSPK 13 1 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 0 SSADKIGEVS(0.625)S(0.375)PK 78.191 0.010465 87547000 6174.4 4145.9 4889.3 6638.3 5362.9 7738.2 5947.2 2050.8 9246.1 6817.3 TRUE FALSE FALSE 5685.689725 4504.253122 5070.501759 6610.832474 5298.95092 6133.210093 6114.062426 2676.079479 8231.825963 7054.200668 0.806000565 0.638520696 0.718791823 0.937148344 0.751176663 0.869440831 0.866726468 0.379359704 1.16693958 1 12.7842669 -13.52287875 0.142144755 1.902008528 0.664518086 0.424137287 0.154210087 65.96529943 0.649538631 16.55794462 0.397108858 3.00E-14 13.52287875 -1.237490442 SSADKIGEVSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SSADKIGEVSSPK 13 1 P35251-2;P35251;A0A1W2PP02 P35251-2 RFC1 Replication factor C subunit 1 1 0 SSADKIGEVS(0.123)S(0.877)PK 85.924 0.0071627 82483000 8516.8 4969 7086.4 8098 6385.7 10176 7637.2 2360.1 10730 8528.3 TRUE FALSE FALSE 7842.686293 5398.498219 7349.028218 8064.492622 6309.554698 8065.382893 7851.479278 3079.683625 9552.945845 8824.65779 0.888724127 0.611751566 0.832783366 0.913858964 0.714991431 0.913959848 0.889720538 0.348986182 1.082528759 1 13.10732462 -2.29656907 0.104594382 1.125944055 4.34E-13 0.375645874 0.159007803 77.40301786 0.767733019 1.222084341 12.49400845 0.005051623 2.29656907 -1.125944055 SSAEDRS(ph)PENTGSSVAVDNFPQVDK ddPTM_HeLa_Curcumin_4h_R1 1 SSAEDRSPENTGSSVAVDNFPQVDK 25 1 H0Y7V5;Q7Z3E2 H0Y7V5 CCDC186 Coiled-coil domain-containing protein 186 1 0 S(0.003)S(0.003)AEDRS(0.815)PENT(0.161)GS(0.009)S(0.009)VAVDNFPQVDK 85.387 3.84E-05 21722000 1932.5 1631.5 1987.2 1781.7 1771.6 2488.5 1781.4 1794.7 2134.7 1692.5 TRUE FALSE FALSE 1779.540586 1772.51959 2060.84738 1774.327797 1750.474827 1972.357049 1831.38129 2341.895768 1900.528751 1751.314249 1.016117231 1.012108245 1.176743341 1.01314073 0.99952069 1.126215384 1.04571826 1.3372219 1.085201443 1 10.77422226 -1.195967273 1.003144247 1.022266686 199.999915 0.623655113 0.062827053 437.0751945 0.875235448 0.008891267 199510.0359 0.063684351 1.195967273 198.9776483 SSAEDRSPENT(ph)GSSVAVDNFPQVDK ddPTM_HeLa_Curcumin_4h_R1 1 SSAEDRSPENTGSSVAVDNFPQVDK 25 1 H0Y7V5;Q7Z3E2 H0Y7V5 CCDC186 Coiled-coil domain-containing protein 186 1 0 S(0.002)S(0.002)AEDRS(0.18)PENT(0.272)GS(0.272)S(0.272)VAVDNFPQVDK 67.478 0.0007656 6494800 1505.1 1196.2 1710 1184.2 1401.7 1163.7 991.09 1105.4 1386.6 1283 TRUE FALSE FALSE 1385.969747 1299.594198 1773.374104 1179.300094 1384.985643 922.3355024 1018.897318 1442.431371 1234.493449 1327.584155 1.043978826 0.978916623 1.335790351 0.88830534 1.043237552 0.694747297 0.767482283 1.086508427 0.92987962 1 10.3745876 -5.293532307 24.13063305 1.033334265 0.84136961 0.243955816 0.146475345 383.0536544 288017.0336 0.019090246 0.042691259 5.09E-06 5.293532307 -0.191964655 SSAPADSERGPKPEPPGS(ph)GSPAPPR ddPTM_HeLa_Curcumin_4h_R1 1 SSAPADSERGPKPEPPGSGSPAPPR 25 2 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 0 SSAPADS(0.007)ERGPKPEPPGS(0.496)GS(0.496)PAPPR 63.125 0.0021451 8092800 818.73 827.85 787.33 911.83 636.41 842.48 1009.1 539.7 951.67 775.32 TRUE FALSE FALSE 753.9266566 899.4056652 816.5091424 908.0570891 628.8212264 667.7401513 1037.41263 704.2520455 847.274182 802.2623123 0.939750808 1.121086771 1.017758319 1.131870555 0.783810004 0.832321475 1.293109017 0.877832642 1.056106175 1 9.647930215 -9.465842635 0.003033918 0.000158673 1.964110228 0 0.148090752 465662.242 325.630832 106942.5187 103860.7616 3.42E-10 9.465842635 1.963951556 SSAPADSERGPKPEPPGSGS(ph)PAPPR ddPTM_HeLa_Curcumin_4h_R1 1 SSAPADSERGPKPEPPGSGSPAPPR 25 2 Q9UKJ3-2;Q9UKJ3 Q9UKJ3-2 GPATCH8 G patch domain-containing protein 8 1 0 S(0.002)S(0.002)APADS(0.087)ERGPKPEPPGS(0.206)GS(0.704)PAPPR 59.636 0.0015143 14570000 2754.1 2734.6 2244.4 2839.7 1858.8 3412.4 2515.4 2241 4661.1 3627.5 TRUE FALSE FALSE 2536.110079 2970.966639 2327.579438 2827.950074 1836.635024 2704.629774 2585.975354 2924.270584 4149.788991 3753.555355 0.675655436 0.791507346 0.620099937 0.75340572 0.489305432 0.720551455 0.688940247 0.77906686 1.10556222 1 11.87404204 -9.297249955 0.580200667 1.055802047 0.678157053 0.715885281 0.089972545 0.556942762 0.262182788 0.114583533 0.018443832 5.04E-10 9.297249955 -0.377644994 SSAQLLEDWGMEDIDHVFSEEDYR ddPTM_HeLa_Curcumin_4h_R1 1 SSAQLLEDWGMEDIDHVFSEEDYR 24 0 F5GWX5;A0A2R8YER1;Q14839-2;Q14839;A0A2R8YFD8;A0A0C4DGG9;A0A2U3TZM0;A0A2R8Y521;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8Y212;A0A2R8Y8C1;A0A2R8Y5Z7;A0A2R8Y685;A0A2R8Y8B3;F5H6N4 F5GWX5 CHD4 Chromodomain-helicase-DNA-binding protein 4 0 0 69.435 0.0041458 17377000 1219.5 1061.6 1612.5 1469.9 1365.1 1871.5 1451.1 1259.4 1181.8 1182.6 FALSE FALSE TRUE 1122.975288 1153.359974 1672.260668 1463.817943 1348.822074 1483.329804 1491.813961 1643.385262 1052.159497 1223.695262 0.917691948 0.942522219 1.366566269 1.196227516 1.102253246 1.212172548 1.219105775 1.342969376 0.859821501 1 10.25702861 -6.778142312 24.99999906 0.958650509 1.229438328 0.78295799 0.079241389 85.97194873 128677.5897 0.012269024 0.016148514 1.67E-07 6.778142312 0.270787819 SSAS(ph)APDVDDPEAFPALA ddPTM_HeLa_Curcumin_4h_R1 1 SSASAPDVDDPEAFPALA 18 0 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 0 S(0.005)S(0.004)AS(0.991)APDVDDPEAFPALA 162.94 2.37E-05 4808700 2011.7 1708.8 1748.2 1583 2164.1 2190.5 2040.9 1926.4 1826.4 1966.7 TRUE FALSE FALSE 1852.471822 1856.501058 1812.98983 1576.449965 2138.294521 1736.165608 2098.162161 2513.750492 1626.048489 2035.042679 0.910286473 0.9122664 0.890885409 0.774652041 1.050736942 0.853134741 1.031016294 1.235232321 0.799024269 1 10.99084334 -4.350930596 3.052755274 0.936709568 1.255622416 0.566491347 0.085797435 0.160479781 2.334590474 0.010530921 0.10859967 4.46E-05 4.350930596 0.318912848 SSASAPDVDDPEAFPALA ddPTM_HeLa_Curcumin_4h_R1 3 SSASAPDVDDPEAFPALA 18 0 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 0 0 ;; ;; 160.53 0.00028264 21942600 10684.2 8971.5 9108.4 9717.6 10059 12352.3 9515.1 9473.8 11623.7 10128.4 FALSE FALSE TRUE 9838.534296 9746.956484 9445.965317 9677.391146 9939.052995 9790.293741 9782.068097 12362.31801 10348.60919 10480.36115 0.93875909 0.930021051 0.901301509 0.923383365 0.948350239 0.934156143 0.93337128 1.179569848 0.987428682 1 13.35540081 -4.258217077 24.86586652 0.954110443 1.179569938 0.85031372 0.029370607 103.42353 798058.0595 0.005174925 0.049309193 5.52E-05 4.258217077 0.225459495 SSATIQNET(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SSATIQNETPK 11 0 F5GX09;Q5HYJ3-3;Q5HYJ3-2;Q5HYJ3 F5GX09 FAM76B Protein FAM76B 1 0 SSATIQNET(1)PK;SSATIQNET(1)PK ; 184.98 0.0002666 55192000 5847.9 5429.6 5621.6 6688.7 6891.1 7715.7 8769.5 3505.8 6122.6 4518.7 TRUE FALSE FALSE 5385.032544 5898.91043 5829.941441 6661.023932 6808.928133 6115.376846 9015.548568 4574.702281 5450.966098 4675.724489 1.151700139 1.261603511 1.246853072 1.424597182 1.456229543 1.307899313 1.928160778 0.97839432 1.165801388 1 12.19097421 -7.004748488 0.601830195 1.029457024 1.468139683 0.249976001 0.224451477 0.514075583 0.400581562 0.057227735 0.082935912 9.89E-08 7.004748488 0.438682659 SSATLWNS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 SSATLWNSPSR 11 0 Q3KQU3-4;Q3KQU3;C9JIR3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 SSATLWNS(0.906)PS(0.094)R 149.57 0.00066708 31886000 2649.8 1835.6 2640.8 2332 2752.9 4315.9 3403.5 704.29 3360.6 2056.6 TRUE FALSE FALSE 2440.065534 1994.261085 2738.670371 2322.350802 2720.073465 3420.73369 3498.99305 919.0247788 2991.950588 2128.066697 1.1466114 0.937123394 1.286928824 1.09129606 1.27818995 1.607437255 1.644212118 0.431859011 1.405947752 1 11.05532765 -6.364110113 1.450277906 1.063026756 1.278893828 0 0.339194943 0.788779199 3.266980358 0.051188494 0.091078858 4.32E-07 6.364110113 0.215867072 SSATLWNSPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SSATLWNSPSR 11 0 Q3KQU3-4;Q3KQU3;C9JIR3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 SSATLWNS(0.446)PS(0.554)R 149.82 0.00064798 55143000 3458.4 2527.5 3256.7 3088.4 3178.2 5589.2 4049.9 1173.1 3915.8 2431.6 TRUE FALSE FALSE 3184.663991 2745.965838 3377.396167 3075.621019 3140.302041 4429.936917 4163.529294 1530.77279 3486.246537 2516.097919 1.265715442 1.091358892 1.342315075 1.222377315 1.248084193 1.760637725 1.654756463 0.608391581 1.385576654 1 11.29697235 -8.996920801 0.343700477 0.910129291 1.343636771 0 0.31786528 4.058305562 0.736582841 0.683550797 0.141678392 1.01E-09 8.996920801 0.43350748 SSATSGDIWPGLS(ph)AYDNSPR ddPTM_HeLa_Curcumin_4h_R1 1 SSATSGDIWPGLSAYDNSPR 20 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 S(0.002)S(0.002)AT(0.009)S(0.01)GDIWPGLS(0.826)AY(0.1)DNS(0.051)PR 52.298 0.01462 6644700 1832.9 2132.6 1784.8 2451.3 2140.9 2350.9 1886.3 1676.3 1986.2 1606.4 TRUE FALSE FALSE 1687.824031 2316.932441 1850.946258 2441.15717 2115.371166 1863.29684 1939.224501 2187.396153 1768.318829 1662.22228 1.015402122 1.39387642 1.113537148 1.468610546 1.272616298 1.120967311 1.166645715 1.315946838 1.063828135 1 10.6988976 -7.287379743 22.00709987 1.007273125 1.257652956 0.499939955 0.108505354 88.21351712 74837.5814 0.017492298 0.020009454 5.16E-08 7.287379743 0.250379831 SSATSGDIWPGLSAYDNS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 SSATSGDIWPGLSAYDNSPR 20 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 SSATSGDIWPGLSAYDNS(1)PR;SSATSGDIWPGLS(0.002)AYDNS(0.998)PR;SSATSGDIWPGLS(0.274)AY(0.008)DNS(0.718)PR;SSATSGDIWPGLSAYDNS(1)PR ;;; 191.61 2.85E-10 260144000 14948.5 13177.1 14372 14539 16552.2 17491.7 13538.1 16380.5 14461.2 12639.6 TRUE FALSE FALSE 13765.31045 14316.06981 14904.63896 14478.84147 16354.82583 13863.72425 13917.94265 21374.83904 12874.84254 13078.82516 1.0524883 1.094599066 1.13960075 1.107044501 1.250481265 1.060012966 1.064158476 1.634308799 0.984403598 1 13.67494533 -4.261439838 9.558682692 1.062342907 1.636121465 0.831525485 0.073801914 0.023926942 57.12903242 0.011313889 0.087989053 5.48E-05 4.261439838 0.573778558 SSATVTGEPPSYSS(ph)GSDSSK ddPTM_HeLa_Curcumin_4h_R1 1 SSATVTGEPPSYSSGSDSSK 20 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 0 SSATVTGEPPS(0.003)YS(0.002)S(0.623)GS(0.372)DSSK 258.17 4.59E-44 6346800 2343.1 1951.9 2085.9 2594.2 2511.2 3565.4 3721.4 1882.9 2357 2086.9 TRUE FALSE FALSE 2157.641163 2120.613539 2163.205289 2583.465888 2481.25558 2825.89585 3825.812468 2456.987542 2098.442997 2159.41962 0.999176419 0.982029393 1.001753096 1.19637048 1.149038176 1.308636739 1.771685518 1.137799953 0.971762495 1 11.0764279 -5.518171037 1.247776233 0.999994235 1.461529695 0.561740357 0.153998918 0.222705106 0.661361972 0.021669465 0.072533949 3.03E-06 5.518171037 0.46153546 RQS(ph)PLPPQK ddPTM_HeLa_Curcumin_4h_R1 7 RQSPLPPQK 9 1 Q01105;B2REB7 Q01105 SET Protein SET 1 0 RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK;RQS(1)PLPPQK ;;;;;; 169.82 0.0014982 508421000 78015 64992.9 67228.4 68868.4 63281.4 70763.6 47860.8 21219.1 78961.5 64874.6 TRUE FALSE FALSE 71840.03043 70610.59667 69719.94364 68583.44081 62526.81064 56086.43169 49203.64524 27688.70591 70299.621 67128.98752 1.070178966 1.051864467 1.038596681 1.021666546 0.931442778 0.835502422 0.732971657 0.412470185 1.047231957 1 16.03464826 -4.164242966 0.804041244 1.036828975 3.20E-21 0.979389828 0.028221279 0.320384533 0.134281787 0.005613679 0.306547221 6.85E-05 4.164242966 -1.036828975 down SSCS(ph)TPLSQANR ddPTM_HeLa_Curcumin_4h_R1 1 SSCSTPLSQANR 12 0 B1AKL4;Q9NRA8;Q9NRA8-3;Q9NRA8-2 B1AKL4 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 0 SSCS(0.5)T(0.5)PLSQANR 207.47 3.92E-09 24416000 4811.4 3415.3 3827.6 4482.4 3897.8 5280 3901.9 1094.8 5223.9 3177.6 TRUE FALSE FALSE 4430.572613 3710.503314 3969.454223 4463.853016 3851.321281 4184.868482 4011.376813 1428.59948 4650.85124 3288.021363 1.347488998 1.128491242 1.20724709 1.35761071 1.171318813 1.27276195 1.219997186 0.43448607 1.414483279 1 11.68300396 -4.260103735 24.86834887 1.191075219 0.434485808 0.787865679 0.122759136 42.13588045 784433.9976 0.01903973 0.159009973 5.49E-05 4.260103735 -0.75658941 GLLPGGTQVLDGTSGFS(ph)PAPK ddPTM_HeLa_Curcumin_4h_R1 2 GLLPGGTQVLDGTSGFSPAPK 21 0 Q96S94;Q96S94-3 Q96S94 CCNL2 Cyclin-L2 1 0 GLLPGGTQVLDGT(0.018)S(0.053)GFS(0.929)PAPK;GLLPGGTQVLDGTSGFS(1)PAPK ; 182 5.85E-10 154606000 13560.5 10706.4 11896.7 12463.1 11427.4 12970.5 10885.8 2758.2 13256 11752.8 TRUE FALSE FALSE 12487.17212 11631.81351 12337.60217 12411.53099 11291.13572 10280.27209 11191.22625 3599.162483 11801.84996 12161.20893 1.026803519 0.956468521 1.014504581 1.02058365 0.92845504 0.845333071 0.920239618 0.295954334 0.970450392 1 13.56999903 -4.163921794 1.991951941 0.996330661 4.21E-30 0.923164879 0.057540893 0.195188848 0.661000853 0.008356981 0.384845327 6.86E-05 4.163921794 -0.996330661 down SSDEENGPPSS(ph)PDLDR ddPTM_HeLa_Curcumin_4h_R1 2 SSDEENGPPSSPDLDR 16 0 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 1 0 SSDEENGPPS(0.064)S(0.936)PDLDR;SSDEENGPPS(0.008)S(0.992)PDLDR ; 255.23 3.20E-40 423250000 9184.9 8474.8 9032.3 8778.4 9574.2 12308 9507.4 10983.8 11231.1 9146 TRUE FALSE FALSE 8457.905473 9207.323949 9367.044984 8742.077307 9460.033918 9755.18206 9774.152056 14332.71006 9999.076429 9463.822819 0.893709195 0.972896907 0.989773917 0.923736367 0.999599644 1.030786633 1.032791108 1.514473626 1.056557865 1 13.20820735 SSDGS(ph)LSHEEDLAK ddPTM_HeLa_Curcumin_4h_R1 2 SSDGSLSHEEDLAK 14 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YEF9;E9PJZ7 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 0 S(0.208)S(0.208)DGS(0.573)LS(0.011)HEEDLAK;S(0.055)S(0.177)DGS(0.754)LS(0.014)HEEDLAK ; 90.706 0.0044288 29241000 8407.1 6699.8 6711.7 7962.3 8802.2 11974 6938.7 3362.5 9986.3 7400.1 TRUE FALSE FALSE 7741.669164 7278.900858 6960.441506 7929.354112 8697.239514 9490.457425 7133.381247 4387.710771 8890.827874 7657.252924 1.01102435 0.95058906 0.908999817 1.035535092 1.135817192 1.239407594 0.931584906 0.573013692 1.16109889 1 12.9026112 -4.298661621 3.924110864 1.020214341 0.545986436 0.664954784 0.100346592 0.095210863 2.8236445 0.012994574 0.118997907 5.03E-05 4.298661621 -0.474227906 SSDGSLS(ph)HEEDLAK ddPTM_HeLa_Curcumin_4h_R1 1 SSDGSLSHEEDLAK 14 0 A0A2R8Y7R9;Q13136-2;Q13136;H0YEF9;E9PJZ7 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 1 0 SSDGS(0.239)LS(0.761)HEEDLAK 220.99 3.57E-14 7228600 1852.3 1511.5 1323.1 1620.6 1618 2470.2 1766.1 872.33 2216.7 1571.2 TRUE FALSE FALSE 1705.6885 1642.147325 1372.13525 1613.894387 1598.706407 1957.852675 1815.652013 1138.299401 1973.533556 1625.799083 1.049138555 1.010055512 0.843975903 0.992677634 0.983335778 1.204240238 1.116775149 0.700147646 1.213885268 1 10.66693326 -4.250832663 24.53850526 1.022865994 0.700147408 0.474137118 0.106797365 722.4372845 1671307.782 0.012463104 0.2371212 5.61E-05 4.250832663 -0.322718587 SSDPGPDIGVVEES(ph)PEKGDEISLR ddPTM_HeLa_Curcumin_4h_R1 1 SSDPGPDIGVVEESPEKGDEISLR 24 1 Q7Z2Z1-2;Q7Z2Z1 Q7Z2Z1-2 TICRR Treslin 1 0 SSDPGPDIGVVEES(0.988)PEKGDEIS(0.012)LR 70.67 0.00042436 8129200 1808.9 1409.4 1848.9 1967.3 2246 1813.4 1485 947.52 1758.6 1842.3 TRUE FALSE FALSE 1665.723656 1531.222256 1917.42186 1959.159834 2219.217917 1437.280399 1526.665103 1236.414486 1565.68598 1906.319788 0.873790256 0.803234728 1.005823825 1.027718354 1.164137272 0.753955558 0.800844178 0.648587133 0.821313397 1 10.89657444 -5.044653935 24.49680285 0.95344146 0.737886593 0.478400961 0.1063596 221.9564657 121763.4899 0.014873114 0.037921787 9.02E-06 5.044653935 -0.215554868 EIS(ph)PYENK ddPTM_HeLa_Curcumin_4h_R1 2 EISPYENK 8 0 H0YCZ2;Q8NG31-4;Q8NG31-2;Q8NG31 H0YCZ2 CASC5 Protein CASC5 1 0 EIS(1)PYENK;EIS(0.999)PY(0.001)ENK ; 119.53 0.0084219 24221100 9403.1 8416.3 8733.6 9331.7 9408.2 10605.9 6904.3 2604.7 9667.9 9132.9 TRUE FALSE FALSE 8658.834713 9143.76747 9057.274899 9293.087898 9296.01336 8406.116787 7098.016076 3398.861039 8607.355558 9450.267595 0.91625286 0.967567043 0.958414649 0.983367699 0.983677263 0.88951098 0.751091544 0.35965765 0.910805485 1 13.20613947 -4.163792305 1.397782733 0.963236695 0.003814219 0.97525272 0.028953375 0.182202764 0.263908338 0.004906084 0.260447689 6.86E-05 4.163792305 -0.959422476 down SSDQPLTVPVS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 4 SSDQPLTVPVSPK 13 0 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 0 SSDQPLTVPVS(1)PK;SSDQPLTVPVS(1)PK;SSDQPLTVPVS(1)PK;SSDQPLT(0.001)VPVS(0.999)PK ;;; 209.6 2.48E-09 1112510000 40219.6 33038.5 34855.8 35188.9 32401.1 44133.9 40269 19144.2 38623.6 32879.8 TRUE FALSE FALSE 37036.17622 35894.20072 36147.58661 35043.29766 32014.73804 34980.03165 41398.83976 24981.17845 34386.68771 34022.3706 1.088583058 1.055017628 1.062465254 1.030007523 0.940990809 1.028147981 1.216812322 0.734257431 1.010708164 1 15.05419605 -5.987499684 24.5426905 1.04553118 0.998536516 0.057162215 0.112779457 550.9089238 1081625.398 0.015454705 0.028000834 1.03E-06 5.987499684 -0.046994665 LEEVLTNK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 LEEVLTNKK 9 1 P78417;Q5TA02;P78417-3 P78417 GSTO1 Glutathione S-transferase omega-1 0 1 ; LEEVLTNK(1)K;LEEVLTNK(1)K 187.22 1.91E-17 6361000 3552.7 3796.3 3517.2 2941.5 4706 5580.7 5228.5 4586.1 4329.6 2866.1 FALSE TRUE FALSE 3271.500046 4124.435256 3647.550526 2929.328852 4649.884024 4423.199913 5375.197638 5984.380778 3854.653712 2965.696762 1.10311347 1.390713747 1.229913514 0.987737145 1.567889234 1.49145387 1.812456927 2.017866714 1.299746408 1 11.53415538 -1 0.295128438 1.012035828 9.944081789 0.749406802 0.161794291 12.15127343 0.155412544 0.051463147 57.77058434 0.1 1 8.932045961 up VIQNSTECTDAQQASLLPSVPALKGEIPS(ph)PQLTRPK ddPTM_HeLa_Curcumin_4h_R1 1 VIQNSTECTDAQQASLLPSVPALKGEIPSPQLTRPK 36 2 Q8IWZ3-6;H7C0V5 Q8IWZ3-6 ANKHD1;ANKHD1-EIF4EBP3 Ankyrin repeat and KH domain-containing protein 1 1 0 VIQNSTECTDAQQASLLPS(0.008)VPALKGEIPS(0.966)PQLT(0.026)RPK 82.364 1.38E-08 19343000 1546 1639.2 1474.6 1473.2 1293.9 1724.1 944.83 613.98 1803.2 1601.9 TRUE FALSE FALSE 1423.632469 1780.885144 1529.249973 1467.104289 1278.471088 1366.502225 971.3393869 801.1796756 1605.393471 1657.565906 0.8588693 1.074397789 0.922587734 0.885095599 0.771294271 0.824402952 0.586003479 0.483347101 0.96852467 1 10.69485052 -4.163114219 0.615349778 0.946206139 0.091576627 0.85924046 0.065294753 1.0861593 0.257764762 0.013287511 0.672375977 6.87E-05 4.163114219 -0.854629511 down SSEEIESAFR ddPTM_HeLa_Curcumin_4h_R1 2 SSEEIESAFR 10 0 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2;A0A0D9SFH4 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 ; ; 113.66 0.0042571 5273100 1398.3 1081.16 1350.37 1732.51 1489.93 1474.15 1235.3 1621.01 1419.54 1528.84 FALSE FALSE TRUE 1287.62308 1174.610653 1400.4159 1725.341333 1472.163558 1168.394673 1269.959193 2115.248487 1263.820014 1581.967076 0.813937976 0.742500062 0.88523707 1.090630367 0.930590516 0.73857079 0.802772202 1.337100195 0.798891477 1 10.62750386 SSEGGVGVGPGGGDEPPT(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 SSEGGVGVGPGGGDEPPTSPR 21 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 SSEGGVGVGPGGGDEPPT(0.829)S(0.171)PR 159.44 3.31E-06 8149500 2587.7 1978 2097.3 1987.3 2238.7 3117.7 2662.2 1843.7 2255 2081 TRUE FALSE FALSE 2382.880814 2148.969506 2175.027783 1979.077079 2212.004965 2471.053876 2736.894167 2405.835643 2007.632142 2153.314595 1.106610627 0.997982139 1.010083612 0.919084041 1.027255827 1.147558226 1.271014543 1.117270857 0.932345021 1 11.07234339 -5.145978353 3.973704635 1.032932333 1.196729125 0.58195508 0.066034417 0.137660117 3.767866734 0.009424487 0.02576405 7.15E-06 5.145978353 0.163796792 SSEGGVGVGPGGGDEPPTS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 SSEGGVGVGPGGGDEPPTSPR 21 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 SSEGGVGVGPGGGDEPPT(0.01)S(0.99)PR;SSEGGVGVGPGGGDEPPT(0.152)S(0.848)PR ; 230.27 2.46E-29 176004000 7370 6356.4 6281.9 6238.8 7124.7 9410.1 6877.1 5298.1 8036.3 6774.2 TRUE FALSE FALSE 6786.656723 6905.818892 6514.71274 6212.985499 7039.742606 7458.339186 7070.052917 6913.466301 7154.737996 7009.602946 0.968194172 0.985194018 0.929398254 0.886353414 1.004299767 1.064017355 1.00862388 0.986285008 1.020705174 1 12.77511701 -5.533802155 24.99967468 0.972711554 1.021143328 0.276032273 0.039709013 236.6658428 541641.0212 0.005903806 0.011816293 2.93E-06 5.533802155 0.048431774 SSEHINEGET(ph)AMLVCK ddPTM_HeLa_Curcumin_4h_R1 1 SSEHINEGETAMLVCK 16 0 A0A087WUV8;P35613-3;P35613-4;P35613-2;P35613;R4GN83;R4GMX5;I3L192;A0A087X2B5 A0A087WUV8 BSG Basigin 1 0 SSEHINEGET(1)AMLVCK 120.77 0.0025839 23969000 315.11 255.9 355.3 358.14 304.89 420.03 297.8 351.79 329.85 430.43 TRUE FALSE FALSE 290.168711 278.0188557 368.4677306 356.6581116 301.2543859 332.9110433 306.1554665 459.0491516 293.6662802 445.3874105 0.651497335 0.624218039 0.827297139 0.800781754 0.676387295 0.747463973 0.68739138 1.030673838 0.659350205 1 8.798916969 -9.422753047 1.157788299 0.9996512 0.741491841 0 0.152051547 0.362792665 0.871672003 0.074549866 0.018886336 3.78E-10 9.422753047 -0.258159359 TSNSLTEDS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 TSNSLTEDSK 10 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0;H7C3N7 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 T(0.003)SNS(0.389)LT(0.083)EDS(0.525)K 120.03 0.0045607 229090000 4910.3 3663.2 3974 3969.5 3902.4 4711.1 2694.8 1350.4 4769.8 3799 TRUE FALSE FALSE 4521.644574 3979.830685 4121.279936 3953.075261 3855.866429 3733.964755 2770.408835 1762.130744 4246.564873 3931.014967 1.150248628 1.012418095 1.048400978 1.005611857 0.980883172 0.949872943 0.704756624 0.448263555 1.080271866 1 11.94068614 -4.160907228 0.878509595 1.064083203 2.10E-16 0.951985641 0.043142888 0.496346538 0.251497849 0.009468246 0.52811296 6.90E-05 4.160907228 -1.064083203 down SSEPVKETVQTTQS(ph)PTPVEK ddPTM_HeLa_Curcumin_4h_R1 1 SSEPVKETVQTTQSPTPVEK 20 1 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 0 SSEPVKETVQTT(0.005)QS(0.908)PT(0.087)PVEK 133.52 4.29E-05 85217000 1819.4 1665.3 1683 1554.8 1834 2308.2 2127 1731.6 1621.7 1625.1 TRUE FALSE FALSE 1675.39257 1809.241112 1745.373461 1548.36665 1812.130748 1829.453301 2186.677895 2259.556869 1443.803567 1681.572104 0.996325145 1.07592241 1.037941493 0.920785166 1.077640824 1.087942228 1.300377123 1.343716908 0.858603425 1 10.71559493 -4.807736598 1.680791633 1.004489184 1.365299803 0.808492848 0.062919159 0.091420607 0.451342359 0.005992751 0.037972765 1.56E-05 4.807736598 0.360810619 SSEPVKETVQTTQSPT(ph)PVEK ddPTM_HeLa_Curcumin_4h_R1 3 SSEPVKETVQTTQSPTPVEK 20 1 A0A0A0MT33;Q9UPN6;Q9UPN6-2 A0A0A0MT33 SCAF8 Protein SCAF8 1 0 SSEPVKETVQTT(0.001)QS(0.119)PT(0.88)PVEK;SSEPVKETVQTT(0.001)QS(0.05)PT(0.949)PVEK;SSEPVKETVQTTQS(0.096)PT(0.904)PVEK ;; 171.78 1.54E-06 203678400 9420 7919.9 8680 8816.5 9266.3 11164.8 9519.1 8168.6 8872.1 7647.7 TRUE FALSE FALSE 8674.39706 8604.460866 9001.688436 8780.019659 9155.805425 8849.094627 9786.180327 10659.16854 7898.852827 7913.457006 1.096157729 1.0873201 1.137516566 1.109504942 1.156991871 1.11823374 1.23665047 1.346967391 0.998154513 1 12.95009236 -1 0.225581664 1.017317014 2.621774667 0.870461902 0.035452388 13.34076331 0.161133284 0.026976849 7.933439381 0.1 1 1.604457653 SSEPVQHEES(ph)IRKPSPEPR ddPTM_HeLa_Curcumin_4h_R1 1 SSEPVQHEESIRKPSPEPR 19 2 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;A0A3B3IRI3 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 SS(0.001)EPVQHEES(0.635)IRKPS(0.363)PEPR 43.794 0.018032 40403000 1525.4 1401.4 1554.8 1260 1328 1959 1070.1 754.02 2015.5 1703.9 TRUE FALSE FALSE 1404.66298 1522.530771 1612.422256 1254.786454 1312.164467 1552.681318 1100.124126 983.9172269 1794.404693 1763.110398 0.796695988 0.863548178 0.914532781 0.711689101 0.744232731 0.880648948 0.623967805 0.558057639 1.017749481 1 10.7839071 -2.523733808 0.10745589 1.099840459 1.20E-19 0.693144786 0.080328454 38.33488977 0.412483747 0.638188762 6.206692703 0.002994099 2.523733808 -1.099840459 SSEQILATLK ddPTM_HeLa_Curcumin_4h_R1 1 SSEQILATLK 10 0 Q9UMS4 Q9UMS4 PRPF19 Pre-mRNA-processing factor 19 0 0 88.056 0.018822 0 1137 908.18 1233.5 1423.2 1241.1 926.83 1016.1 845.02 1138.9 1163.7 FALSE FALSE TRUE 1047.00525 986.6790324 1279.214595 1417.311175 1226.300693 734.5950105 1044.609031 1102.662708 1013.965519 1204.138488 0.869505676 0.819406606 1.062348399 1.177033364 1.01840503 0.610058575 0.86751569 0.915727484 0.842067195 1 10.23378561 -5.308935036 24.99982323 0.960412905 0.804741302 0.279148271 0.125919857 431.2051123 226968.5227 0.01869184 0.041796319 4.91E-06 5.308935036 -0.155671602 SETELK(ac)DTYAR ddPTM_HeLa_Curcumin_4h_R1 1 SETELKDTYAR 11 1 Q13200;Q13200-2;Q13200-3;H7C1H2 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 0 1 SETELK(1)DTYAR 108.7 0.0049342 2953800 373.56 678.67 537.53 637.88 911.87 1045.5 777.03 1333.8 931.59 625.91 FALSE TRUE FALSE 343.9923318 737.3312107 557.4513347 635.2406216 900.9965458 828.6515148 798.8313705 1740.46948 829.3969077 647.6603259 0.531130777 1.138453571 0.860715582 0.980823738 1.391155996 1.279453877 1.233411 2.687318352 1.280604778 1 9.339093561 -1 0.599577627 0.822624501 108.6196119 0.740175226 0.274603811 49.9149193 0.356308355 0.046748476 7069.833984 0.1 1 107.7969874 up SSETGAFRVPS(ph)PGMEEAGCSR ddPTM_HeLa_Curcumin_4h_R1 1 SSETGAFRVPSPGMEEAGCSR 21 1 Q96RL1-2;Q96RL1;Q96RL1-3;Q96RL1-4 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 0 SSET(0.001)GAFRVPS(0.997)PGMEEAGCS(0.001)R 84.159 0.00039435 67411000 1171.5 806.77 838.95 1081.2 817.36 1026.3 875 541.4 903.72 1030.6 TRUE FALSE FALSE 1078.774539 876.5036039 870.042225 1076.726281 807.6135158 813.4338112 899.5501451 706.4703677 804.584177 1066.413273 1.01159144 0.82191738 0.815858398 1.009670742 0.757317577 0.7627754 0.843528647 0.662473344 0.754476897 1 10.05855093 -5.868848829 0.386298232 1.020538127 0.678142332 0.051639554 0.113662821 0.976022175 0.230588526 0.029974974 0.134112614 1.35E-06 5.868848829 -0.342395795 SSFASSSASDAS(ph)KPS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 SSFASSSASDASKPSSPR 18 1 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 2 0 SSFAS(0.001)S(0.001)S(0.001)AS(0.053)DAS(0.885)KPS(0.946)S(0.113)PR;S(0.013)S(0.006)FAS(0.028)S(0.008)S(0.078)AS(0.047)DAS(0.822)KPS(0.918)S(0.081)PR ; 160.03 0.00014042 18092500 5570.5 4837.07 5693.6 6401.49 5509.38 6951.6 5619.04 2510.5 5891 6027 TRUE FALSE FALSE 5129.589047 5255.164777 5904.609825 6375.002331 5443.684242 5509.759799 5776.69514 3275.939893 5244.772039 6236.437801 0.822519074 0.842654885 0.946792065 1.022218538 0.872883594 0.883478674 0.926281208 0.525290237 0.840988431 1 12.60650649 -4.260359818 24.84667531 0.914271636 0.525290103 0.757027645 0.064639611 36.26489771 834532.2034 0.010692517 0.087843017 5.49E-05 4.260359818 -0.388981533 SSFASSSASDASKPS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 SSFASSSASDASKPSSPR 18 1 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 0 SSFASSSASDAS(0.01)KPS(0.495)S(0.495)PR 128.4 9.17E-05 27062000 3133.3 2724.7 2845.8 2462.3 2776.6 3505.4 2588.1 1327.3 3462.5 2363.3 TRUE FALSE FALSE 2885.295999 2960.210927 2951.267851 2452.111655 2743.490858 2778.340526 2660.71512 1731.98766 3082.672413 2445.424499 1.179875314 1.210510048 1.206852983 1.002734558 1.121887369 1.136138338 1.088038139 0.708256444 1.26058785 1 11.25586921 -4.262054738 5.460747769 1.104098272 0.693607088 0.675673365 0.086354525 0.071780726 8.083060391 0.012251912 0.109711098 5.47E-05 4.262054738 -0.410491184 SAS(ph)FSQGTR ddPTM_HeLa_Curcumin_4h_R1 1 SASFSQGTR 9 0 Q9UQC2-2;Q9UQC2 Q9UQC2-2 GAB2 GRB2-associated-binding protein 2 1 0 S(0.012)AS(0.795)FS(0.192)QGTR 114.86 0.0075799 45339000 2116.9 1638.8 1577.9 1757.2 1694.4 2101.9 1427.9 482.43 1806 1666.4 TRUE FALSE FALSE 1949.345131 1780.45057 1636.378362 1749.929172 1674.195387 1665.942247 1467.963031 629.5206862 1607.886318 1724.307276 1.130509137 1.032559912 0.949006239 1.01485924 0.970937959 0.966151608 0.85133494 0.365086139 0.932482476 1 10.75180117 -4.159678787 1.431428977 1.042679122 3.10E-21 0.902701027 0.061658555 0.328663918 0.49955044 0.009727471 0.522172596 6.92E-05 4.159678787 -1.042679122 down SSFDWLTGSSTDPLVDHT(ph)SPSSDSLLFAHK ddPTM_HeLa_Curcumin_4h_R1 2 SSFDWLTGSSTDPLVDHTSPSSDSLLFAHK 30 0 P78527-2;P78527 P78527-2 PRKDC DNA-dependent protein kinase catalytic subunit 1 0 SSFDWLTGSSTDPLVDHT(0.5)S(0.5)PSSDSLLFAHK;SSFDWLTGSSTDPLVDHT(0.414)S(0.414)PS(0.069)S(0.087)DS(0.015)LLFAHK ; 123.65 1.74E-12 23246000 1678.27 1666.34 1658.11 1361.04 2329.92 4293.7 2630.05 1709.23 2331.64 1705.25 TRUE FALSE FALSE 1545.433159 1810.371005 1719.561015 1355.408377 2302.137226 3403.13822 2703.842125 2230.366359 2075.864925 1764.507311 0.87584401 1.025992351 0.974527566 0.768151182 1.304691237 1.928662012 1.53234963 1.264016502 1.176455837 1 10.78504969 -5.554018173 5.499919538 0.940737665 1.57952553 0.694006979 0.180731814 0.060700044 5.007812073 0.023243245 0.047980934 2.79E-06 5.554018173 0.638787865 SSFFSDRGS(ph)GSR ddPTM_HeLa_Curcumin_4h_R1 2 SSFFSDRGSGSR 12 1 A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8Y5G6;A0A2R8YFR4;A0A0D9SFB3;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;A0A0D9SF53;A0A2R8YF78;F6S8Q4;A0A0D9SG12;A0A2R8YDH3;A0A087WX09;A0A2R8YF89;A0A2R8YCU0;A0A2R8Y650 A0A2R8YCW1 DDX3X ATP-dependent RNA helicase DDX3X 1 0 SSFFSDRGS(0.999)GS(0.001)R;SSFFS(0.001)DRGS(0.928)GS(0.071)R ; 148.13 0.0036722 87277000 8935.7 5742.5 7464.8 7366.3 6321.2 10450.5 11731.7 4377.9 6117.5 6519.6 TRUE FALSE FALSE 8228.429916 6238.856112 7741.452055 7335.820202 6245.823819 8282.948499 12060.85993 5712.701557 5446.425555 6746.155615 1.219721333 0.92480169 1.147535352 1.087407499 0.925834531 1.227802762 1.787812291 0.846808447 0.80733767 1 12.71984988 -5.000849661 24.99999772 1.083798196 1.364934619 0.16973315 0.245665581 34.54346808 1016534.1 0.028918366 0.085249572 9.98E-06 5.000849661 0.281136423 FVHGPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 FVHGPSPR 8 0 Q5T200-2;Q5T200;Q5T9K0 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 0 FVHGPS(1)PR 95.483 0.0083615 13602000 4362.4 3366.5 3231.3 3789.5 3326.9 4641.4 3074.8 957.44 4185.8 3432.1 TRUE FALSE FALSE 4017.111437 3657.485259 3351.054821 3773.820053 3287.22889 3678.721321 3161.070613 1249.359048 3726.628212 3551.36522 1.131145683 1.029881477 0.943596227 1.062639244 0.925624003 1.035861167 0.890100121 0.351796836 1.049350878 1 11.79415802 -4.158766223 1.877600176 1.042994813 1.47E-11 0.920815799 0.058558635 0.246792879 0.714151502 0.01001811 0.488769915 6.94E-05 4.158766223 -1.042994813 down SSFLVDCSK ddPTM_HeLa_Curcumin_4h_R1 1 SSFLVDCSK 9 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;A0A0A0MT44 O75369-8 FLNB Filamin-B 0 0 97.565 0.012372 5065800 4359.4 3191.2 3451.7 4081.7 4455.7 4846.5 3850.6 4208.5 4333.9 3541.8 FALSE FALSE TRUE 4014.34889 3467.033108 3579.623038 4064.811007 4402.568688 3841.281269 3958.637473 5491.652276 3858.482013 3664.877286 1.095356973 0.946016152 0.976737489 1.109126088 1.201286795 1.048133667 1.080155531 1.498454613 1.052827069 1 11.83954918 SSFSSTSES(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 2 SSFSSTSESPTR 12 0 Q6ZMT1-2;Q6ZMT1 Q6ZMT1-2 STAC2 SH3 and cysteine-rich domain-containing protein 2 1 0 SSFSSTSES(0.732)PT(0.268)R;SSFSS(0.001)T(0.003)S(0.085)ES(0.827)PT(0.085)R ; 143.55 0.00097814 12294100 4118.8 3371.2 3145.9 4031.1 3862.4 5640.6 4255.1 2699.5 4423.8 3493.1 TRUE FALSE FALSE 3792.792634 3662.591506 3262.489821 4014.420376 3816.343403 4470.675977 4374.486654 3522.565123 3938.520208 3614.484965 1.049331418 1.013309376 0.902615408 1.110647966 1.055847082 1.236877735 1.210265555 0.974569035 1.089649078 1 11.81957437 -6.031782457 23.49316629 1.014398084 1.127894834 0.296041487 0.081822243 270.8675615 200221.5387 0.011536348 0.019147632 9.29E-07 6.031782457 0.11349675 SSFSSTSESPT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SSFSSTSESPTR 12 0 Q6ZMT1-2;Q6ZMT1 Q6ZMT1-2 STAC2 SH3 and cysteine-rich domain-containing protein 2 1 0 SSFSSTS(0.001)ES(0.298)PT(0.701)R 133.05 0.0061856 0 868.09 643.92 877.52 895.89 793.13 971.78 768.59 688.88 724.22 839.48 TRUE FALSE FALSE 799.3797605 699.5775755 910.0416631 892.1830446 783.6724428 770.2218738 790.1545668 898.9163408 644.7748779 868.6518675 0.920253315 0.805360124 1.047648312 1.027089307 0.902170907 0.886686488 0.909633187 1.034840739 0.742270755 1 9.762634289 -7.226700005 0.005988639 1.900999782 1.65E-07 0 0.104045732 9131.212056 46.51306214 7366.380506 7395.650262 5.93E-08 7.226700005 -1.900999617 SSFTPS(ph)SPENVIGDFLLQDR ddPTM_HeLa_Curcumin_4h_R1 1 SSFTPSSPENVIGDFLLQDR 20 0 F5H212;P15822 F5H212 HIVEP1 Zinc finger protein 40 1 0 SSFTPS(0.5)S(0.5)PENVIGDFLLQDR 90.872 0.0010871 708170 859.27 672.33 559.59 796.12 803.1 239.56 501.5 433.13 777.08 535.66 TRUE FALSE FALSE 791.2578728 730.4432094 580.3288977 792.8258664 793.523557 189.8725556 515.5707403 565.1893431 691.8362682 554.2741451 1.427556886 1.31783742 1.047006978 1.4303858 1.431644546 0.34256073 0.930172812 1.019692779 1.248184268 1 9.114455902 -5.282009655 24.96416068 1.234074584 0.780745083 0.523169179 0.219872296 556.1027708 674887.5199 0.035115192 0.078602943 5.22E-06 5.282009655 -0.453329501 SSFYPDGGDQETAK ddPTM_HeLa_Curcumin_4h_R1 1 SSFYPDGGDQETAK 14 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 0 237.49 5.95E-38 1553000 1585.7 1132 1134.1 1446.1 1202.3 1771.1 1272.7 1187 1476.9 1137.4 FALSE FALSE TRUE 1460.190172 1229.845036 1176.130744 1440.116421 1187.963358 1403.753896 1308.408537 1548.910836 1314.887765 1176.924565 1.240682891 1.044965049 0.999325512 1.223626784 1.009379354 1.19273056 1.111718266 1.316066366 1.117223485 1 10.20080614 -9.609333347 1.413111036 1.000010856 1.148481484 0.048461424 0.10489346 0.499081418 1.789077171 0.069738019 0.016056599 2.46E-10 9.609333347 0.148470628 SSFYSGGWQEGSS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 SSFYSGGWQEGSSSPR 16 0 D3DPQ1;Q96BR9-2;Q96BR9 D3DPQ1 ZBTB8A Zinc finger and BTB domain-containing protein 8A 1 0 SSFYSGGWQEGS(0.144)S(0.428)S(0.428)PR 80.719 0.012129 6844100 1653.8 969.76 1156.2 1396.7 1344.8 1490.5 1189.8 863.07 1532.4 1020.4 TRUE FALSE FALSE 1522.899985 1053.581733 1199.049789 1390.920825 1328.764138 1181.353499 1223.182586 1126.21607 1364.299554 1055.858824 1.442332962 0.997843376 1.135615635 1.317335986 1.258467617 1.118855544 1.158471718 1.066635088 1.292123078 1 10.04420123 -5.228547627 21.13971288 1.20270338 1.119035631 0.091474457 0.1317295 297.8615119 191432.3948 0.024939871 0.063568717 5.91E-06 5.228547627 -0.083667749 SSFYSGGWQEGSSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SSFYSGGWQEGSSSPR 16 0 D3DPQ1;Q96BR9-2;Q96BR9 D3DPQ1 ZBTB8A Zinc finger and BTB domain-containing protein 8A 1 0 SSFYSGGWQEGS(0.01)S(0.037)S(0.952)PR 99.069 0.0031503 18599000 1467.5 1170.7 1256.9 1303.5 1223.6 1642.3 1016.9 886.04 1466.4 1126.9 TRUE FALSE FALSE 1351.345827 1271.890091 1303.48182 1298.106462 1209.009369 1301.668467 1045.431477 1156.189517 1305.539589 1166.059691 1.158899357 1.09075899 1.11785171 1.113241863 1.036833173 1.116296599 0.896550567 0.991535447 1.11961643 1 10.18742593 -4.764984286 24.99977279 1.082925381 0.944042993 0.594155746 0.048933033 57.86980421 408130.3636 0.008919496 0.028398576 1.72E-05 4.764984286 -0.138882388 SSFYVNGLTLGGQK ddPTM_HeLa_Curcumin_4h_R1 2 SSFYVNGLTLGGQK 14 0 P07737;K7EJ44;I3L3D5 P07737 PFN1 Profilin-1 0 0 ; ; 263.44 8.59E-77 2601450 1586.42 787.69 1640.21 790.17 1353.83 3741.8 2324.03 1844.08 1262.86 1502.77 FALSE FALSE TRUE 1460.853183 855.7744137 1700.997625 786.9004859 1337.686461 2965.708501 2389.236027 2406.331503 1124.327418 1554.991146 0.939460773 0.550340377 1.093895377 0.50604821 0.860253427 1.907218899 1.53649494 1.547488878 0.723044257 1 10.60269065 -5.271552999 24.97381733 0.905619026 1.651010309 0.762544152 0.213599099 246.510062 608713.6958 0.029425214 0.066506546 5.35E-06 5.271552999 0.745391284 SQGSPEDSAPQAS(ph)PGPSK ddPTM_HeLa_Curcumin_4h_R1 2 SQGSPEDSAPQASPGPSK 18 0 Q9P107;Q9P107-2 Q9P107 GMIP GEM-interacting protein 1 0 SQGSPEDSAPQAS(1)PGPSK;SQGSPEDSAPQAS(1)PGPSK ; 298.42 4.76E-83 14287500 5422 3964 4683.6 4710.2 4904 5478.3 4087.6 1442.38 5531.4 4053.5 TRUE FALSE FALSE 4992.842979 4306.630497 4857.178336 4690.71044 4845.523003 4342.038827 4202.287055 1882.155022 4924.619259 4194.358823 1.190370969 1.026767303 1.158026421 1.118337901 1.155247609 1.035209196 1.001890213 0.448734861 1.17410538 1 12.03423457 -4.158164011 2.140094445 1.096435174 0.147428021 0.904490748 0.063783013 0.251350827 1.003296438 0.010828296 0.501262357 6.95E-05 4.158164011 -0.949007153 down SSGCDVNLPGVNVK ddPTM_HeLa_Curcumin_4h_R1 1 SSGCDVNLPGVNVK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 150.51 0.00099613 2243100 1298.1 1200.9 1217 1404.5 1749 1830.5 1287.8 1238.6 1881.3 1232.2 FALSE FALSE TRUE 1195.354015 1304.700445 1262.103091 1398.688551 1728.144317 1450.833666 1323.932202 1616.243438 1674.926097 1275.018858 0.937518694 1.023279331 0.989870136 1.096994403 1.35538726 1.137891927 1.038362839 1.267623163 1.313648097 1 10.31630287 -6.123384075 3.63138142 0.975785834 1.187491563 0.084488229 0.133971056 0.124844731 2.982946481 0.012212423 0.021029138 7.53E-07 6.123384075 0.211705729 SSGDPEQIKEDS(ph)LS(ph)EESADAR ddPTM_HeLa_Curcumin_4h_R1 1 SSGDPEQIKEDSLSEESADAR 21 1 Q9BVS4;Q9BVS4-2 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 2 0 SSGDPEQIKEDS(0.91)LS(0.91)EES(0.179)ADAR 61.561 0.0072317 19235000 4818.8 3774 4314.5 4617.8 4144.7 4345.9 3278.2 3049 4744.7 4468.8 TRUE FALSE FALSE 4437.386895 4100.207743 4474.399165 4598.692767 4095.277159 3444.511352 3370.177469 3978.626064 4224.218281 4624.090467 0.95962372 0.88670578 0.967627947 0.994507525 0.885639498 0.744905701 0.728830349 0.860412678 0.913524143 1 12.17495391 -5.489479241 3.449084818 0.972113239 0.77439824 0.720860707 0.047903392 0.078582303 1.91843401 0.006681973 0.015271943 3.24E-06 5.489479241 -0.197714999 SSGDPEQIKEDS(ph)LSEESADAR ddPTM_HeLa_Curcumin_4h_R1 4 SSGDPEQIKEDSLSEESADAR 21 1 Q9BVS4;Q9BVS4-2 Q9BVS4 RIOK2 Serine/threonine-protein kinase RIO2 1 0 SSGDPEQIKEDS(0.963)LS(0.018)EES(0.018)ADAR;SSGDPEQIKEDS(0.746)LS(0.249)EES(0.004)ADAR;SSGDPEQIKEDS(0.692)LS(0.251)EES(0.058)ADAR;SSGDPEQIKEDS(0.453)LS(0.453)EES(0.094)ADAR ;;; 104.7 3.06E-05 151238800 14905.1 13164.3 14092.9 14838.4 15233.4 17122.3 13726.7 12383.4 15783.4 14048.3 TRUE FALSE FALSE 13725.34561 14302.16343 14615.19527 14777.00263 15051.75165 13570.94197 14111.83426 16159.04165 14052.00051 14536.47738 0.944200252 0.983880968 1.005415197 1.016546323 1.035446984 0.933578447 0.970787756 1.111620184 0.966671646 1 13.82739008 -6.833376602 3.948762537 0.973273769 1.008175729 0.150543264 0.044837204 0.390308087 11.99582419 0.007527433 0.010147678 1.47E-07 6.833376602 0.03490196 SSGEIVYCGQVFEKS(ph)PLR ddPTM_HeLa_Curcumin_4h_R1 2 SSGEIVYCGQVFEKSPLR 18 1 M0R0P7;M0R3D6;M0R1A7;M0R117;Q02543 M0R0P7 RPL18A 60S ribosomal protein L18a 1 0 SSGEIVYCGQVFEKS(1)PLR;SSGEIVY(0.001)CGQVFEKS(0.999)PLR ; 99.414 0.00068543 419620000 5491.7 4800.5 5165.8 4852.4 4570.5 5875.7 4487 4571.7 5340.7 4761.1 TRUE FALSE FALSE 5057.02615 5215.433829 5357.249092 4832.322055 4515.999773 4657.013587 4612.893144 5965.590284 4754.838572 4926.547871 1.026484728 1.058638618 1.087424548 0.980873866 0.916666171 0.945289422 0.936333771 1.210906793 0.965146122 1 12.26636136 SSGGREDLES(ph)SGLQR ddPTM_HeLa_Curcumin_4h_R1 1 SSGGREDLESSGLQR 15 1 Q9UK76;J3KT51;Q9UK76-2;Q9UK76-3;J3KSH8 Q9UK76;Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 1 0 SSGGREDLES(0.739)S(0.261)GLQR 79.514 0.0070921 228270000 1264.9 1161.5 1428.7 1562.3 1551.8 1943.4 1563.4 490.93 1365.9 1733.5 TRUE FALSE FALSE 1164.78183 1261.894884 1481.648879 1555.835617 1533.295799 1540.316933 1607.264796 640.612297 1216.064187 1793.738996 0.649359708 0.703499722 0.826011411 0.867370125 0.854804295 0.858718541 0.89604162 0.357137966 0.677949351 1 10.80875427 -9.489120553 1.236800032 0.999805982 0.755428134 0 0.180731991 0.503475667 1.379851907 0.103577627 0.02534167 3.24E-10 9.489120553 -0.244377848 SSGGREDLESS(ph)GLQR ddPTM_HeLa_Curcumin_4h_R1 2 SSGGREDLESSGLQR 15 1 Q9UK76;J3KT51;Q9UK76-2;Q9UK76-3;J3KSH8 Q9UK76;Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 1 0 SSGGREDLES(0.178)S(0.822)GLQR;SSGGREDLES(0.025)S(0.975)GLQR ; 188.39 3.59E-05 402710000 3838.1 3277.4 4152.7 3967.8 4004.8 5007.8 4501.4 1134.5 3770.4 3970.2 TRUE FALSE FALSE 3534.310335 3560.683852 4306.602715 3951.382295 3957.045376 3969.12583 4627.697169 1480.403827 3356.796553 4108.164154 0.860313805 0.866733587 1.048303464 0.961836515 0.96321501 0.966155607 1.126463548 0.360356542 0.817103803 1 12.00427811 -4.25083249 24.98456277 0.951500264 0.360356207 0.807256218 0.087382429 474.2756229 1117136.542 0.011572822 0.22378869 5.61E-05 4.25083249 -0.591144057 SSGGREDLESSGLQR ddPTM_HeLa_Curcumin_4h_R1 4 SSGGREDLESSGLQR 15 1 Q9UK76;J3KT51;Q9UK76-2;Q9UK76-3;J3KSH8 Q9UK76;Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 0 0 ;;; ;;; 156.2 0.00050091 51217300 8231.3 7067.3 6887 7447 7495.9 9391.1 7511.3 6922.3 8975.1 7675 FALSE FALSE TRUE 7579.783919 7678.165921 7142.238278 7416.186287 7406.516288 7443.28 7722.046862 9032.877404 7990.553985 7941.705679 0.954427704 0.966815723 0.899333036 0.933827894 0.932610271 0.937239467 0.972341103 1.137397653 1.006150858 1 12.95523318 -4.263362384 5.09588473 0.962635114 1.145311865 0.750336915 0.031243646 0.070845122 5.942570271 0.004913827 0.045281556 5.45E-05 4.263362384 0.182676751 SSGLESSEAR ddPTM_HeLa_Curcumin_4h_R1 1 SSGLESSEAR 10 0 Q8N6H7;E9PMU9;H0YDN9;A0A0D9SF70;G5E9L0;Q8N6H7-3;Q8N6H7-2 Q8N6H7 ARFGAP2 ADP-ribosylation factor GTPase-activating protein 2 0 0 116.37 4.36E-07 0 277.1 237.76 203.51 214.21 405.28 470.55 213.43 190.76 297.97 161.7 FALSE FALSE TRUE 255.1672426 258.310915 211.0522596 213.3236558 400.4473007 372.9526258 219.4182714 248.9218458 265.2834365 167.319063 1.525033897 1.543822386 1.261376055 1.274951294 2.393315463 2.228990643 1.311376406 1.487707625 1.585494395 1 7.386458013 -5.832829447 24.99943812 1.281170523 1.843184831 0.314969732 0.340768292 37.72124705 13208.54893 0.055091583 0.099862007 1.47E-06 5.832829447 0.562014308 SSGNS(ph)PTPVSR ddPTM_HeLa_Curcumin_4h_R1 2 SSGNSPTPVSR 11 0 O95429;O95429-2;H0YBT1 O95429 BAG4 BAG family molecular chaperone regulator 4 1 0 S(0.213)S(0.032)GNS(0.694)PT(0.061)PVSR;S(0.279)S(0.04)GNS(0.621)PT(0.055)PVS(0.004)R ; 98.654 0.011912 421790000 9724.4 8022.5 8222.7 8745.2 8677.8 9459 6954.6 5165.4 9543.3 8211.1 TRUE FALSE FALSE 8954.703479 8715.929152 8527.440495 8709.01468 8574.322903 7497.096775 7149.727359 6740.306681 8496.423866 8496.435114 1.053936546 1.025833663 1.003649222 1.025019854 1.009167114 0.882381455 0.841497318 0.79330997 0.999998676 1 13.05264194 -5.086950611 1.749372501 1.02508603 0.806440254 0.951951602 0.018682212 0.064394181 0.368560092 0.003343766 0.013605443 8.19E-06 5.086950611 -0.218645776 SSGNSSS(ph)SGSGSGSTSAGSSSPGAR ddPTM_HeLa_Curcumin_4h_R1 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 0 SSGNS(0.005)S(0.044)S(0.393)S(0.393)GS(0.148)GS(0.017)GSTSAGSSSPGAR 299.9 1.09E-108 3994400 594.65 654.25 583.47 739.1 869.44 835.87 455.19 488.07 1048.8 587.59 TRUE FALSE FALSE 547.582825 710.8004547 605.0939115 736.0418 859.0724958 662.5011398 467.9614063 636.8802962 933.749264 608.0087088 0.900616746 1.16906295 0.995205994 1.210577726 1.412927946 1.089624425 0.769662341 1.047485483 1.535749818 1 9.247948178 -7.265823662 24.7537408 0.953069019 1.098524578 0 0.241321577 485.377157 2740447.325 0.028399291 0.033078238 5.42E-08 7.265823662 0.145455558 SSGNSSSSGSGSGSTSAGS(ph)SSPGAR ddPTM_HeLa_Curcumin_4h_R1 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 0 SSGNSSSSGSGSGSTS(0.001)AGS(0.49)S(0.255)S(0.255)PGAR 195.94 1.27E-17 1140000 164.46 453.19 515.89 578.97 345.94 689.98 393.24 0 550.3 511.21 TRUE FALSE FALSE 151.4428175 492.3617242 535.0093372 576.5743755 341.8148914 546.8703703 404.273256 0 489.9334668 528.9745094 0.286295114 0.930785351 1.011408542 1.089985179 0.646184051 1.033831235 0.764258483 0 0.926194851 1 9.047054392 -4.261011913 24.99987749 0.754914422 5.74E-05 0.48308887 0.246516614 31.92311033 1866363.059 0.04410313 0.347036998 5.48E-05 4.261011913 -0.754857042 SSGNSSSSGSGSGSTSAGSS(ph)SPGAR ddPTM_HeLa_Curcumin_4h_R1 1 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 0 SSGNSSSSGSGSGSTSAGS(0.008)S(0.851)S(0.142)PGAR 150.95 1.89E-08 57343000 369.64 283.69 269.79 459.55 386.82 501.67 170.32 108.47 479.42 253.97 TRUE FALSE FALSE 340.382604 308.2108995 279.7886547 457.6485039 382.2074241 397.617987 175.0987208 141.5420037 426.8288254 262.7954386 1.295237869 1.172816778 1.064663284 1.74146289 1.454391393 1.5130323 0.666292846 0.538601448 1.624186583 1 8.037796424 -4.65697949 6.550366547 1.224212594 0.575217561 0.543366025 0.255154886 0.128053331 6.951426636 0.035372867 0.135155417 2.20E-05 4.65697949 -0.648995033 SSGNSSSSGSGSGSTSAGSS(ph)SPGARR ddPTM_HeLa_Curcumin_4h_R1 2 SSGNSSSSGSGSGSTSAGSSSPGARR 26 1 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 0 SSGNSSSSGSGSGSTS(0.002)AGS(0.1)S(0.449)S(0.449)PGARR;SSGNSSSSGSGSGST(0.002)S(0.019)AGS(0.166)S(0.584)S(0.228)PGARR ; 131.4 2.53E-08 39217100 481.79 238.32 289.02 689.66 357.59 597.16 34.062 152.23 916.57 595.06 TRUE FALSE FALSE 443.6558131 258.9193189 299.7313354 686.8063697 353.3259728 473.3022846 35.01768805 198.6442262 816.0245641 615.7382907 0.720526594 0.420502221 0.486783655 1.115419294 0.573824916 0.768674438 0.056871058 0.322611456 1.32527825 1 9.266173478 -5.796148275 0.160682068 1.13277697 3.66E-15 0.454210417 0.271426602 8.644789813 0.478985159 0.88901832 2.497152333 1.60E-06 5.796148275 -1.13277697 SSGNSSSSGSGSGSTSAGSSS(ph)PGAR ddPTM_HeLa_Curcumin_4h_R1 2 SSGNSSSSGSGSGSTSAGSSSPGAR 25 0 E5RHJ2;E5RG56;Q12797-7;Q12797-6;Q12797-11;Q12797-2;Q12797 E5RHJ2 ASPH Aspartyl/asparaginyl beta-hydroxylase 1 0 SSGNSSSSGSGSGSTS(0.003)AGS(0.054)S(0.018)S(0.925)PGAR;SSGNSSSSGSGS(0.003)GS(0.001)T(0.035)S(0.109)AGS(0.163)S(0.163)S(0.528)PGAR ; 149.8 3.22E-08 48558520 450.1 528.59 503.97 773.5 664.8 957.77 347.27 51.763 990.17 473.56 TRUE FALSE FALSE 414.4741101 574.2789642 522.6475715 770.299462 656.8726942 759.1177057 357.0134616 67.54530041 881.5508283 490.0161748 0.84583761 1.1719592 1.066592489 1.571987827 1.340512269 1.54916867 0.728574851 0.137843002 1.799023938 1 8.936685561 -2.673020139 9.424622218 1.005531053 1.022011014 0 0.473793754 0 0 0.053831307 0 0.002123146 2.673020139 0.016479961 SSGPPGMSSQK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 SSGPPGMSSQKR 12 1 Q9UGU0-2;Q9UGU0 Q9UGU0-2 TCF20 Transcription factor 20 0 1 SSGPPGMSSQK(1)R 173.64 3.22E-34 0 145.51 0 0 0 0 166.28 0 129.76 136.64 0 FALSE TRUE FALSE 133.99273 0 0 0 0 131.7916536 0 169.3232267 121.6509339 0 0 SSGPTSLFAVTVAPPGAR ddPTM_HeLa_Curcumin_4h_R1 2 SSGPTSLFAVTVAPPGAR 18 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;A0A1X7SBS1;A0A1W2PP22 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 0 ; ; 244.46 1.79E-48 9666600 850.44 849.91 1130.45 1017.86 896.8 1339.24 1057.58 1144.27 1087.11 1064.48 FALSE FALSE TRUE 783.1267766 923.3724333 1172.345471 1013.648365 886.1062457 1061.466528 1087.252848 1493.152655 967.8567528 1101.470601 0.710982913 0.838308742 1.064345676 0.920268198 0.804475621 0.963681216 0.987092027 1.355599191 0.878695039 1 10.10521527 -3.222087769 1.043637789 0.874323493 4.503421772 0.671515918 0.095619768 7.271405279 1.179011081 0.018995774 48.81490254 0.00059967 3.222087769 3.629098279 SSGPYGGGGQYFAK ddPTM_HeLa_Curcumin_4h_R1 1 SSGPYGGGGQYFAK 14 0 F8W6I7;P09651-2;P09651;P09651-3;H0YH80;Q32P51 F8W6I7 HNRNPA1;HNRNPA1L2 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;Heterogeneous nuclear ribonucleoprotein A1-like 2" 0 0 180.88 6.97E-08 2184100 585.96 505.2 525.91 347.14 697.61 675.18 466.61 405.19 389.45 392.12 FALSE FALSE TRUE 539.5806477 548.8672369 545.4006872 345.7036267 689.2914564 535.1400572 479.7018208 528.7305657 346.7283094 405.7461408 1.329847886 1.35273557 1.344191928 0.852019507 1.69882443 1.318903628 1.182270815 1.303106826 0.854544935 1 8.664433563 -9.241810345 0.823458497 0.986412631 1.298408942 0.334902824 0.201377374 0.772442845 0.878278058 0.156070492 0.036505196 5.73E-10 9.241810345 0.311996311 ELKVAMK(ac)KTFFSK ddPTM_HeLa_Curcumin_4h_R1 1 ELKVAMKKTFFSK 13 3 Q9Y4A9 Q9Y4A9 OR10H1 Olfactory receptor 10H1 0 1 ELKVAMK(0.5)K(0.5)TFFSK 56.205 0.012773 0 177.24 69.948 194.37 238.65 236.6 395.6 218.59 386 147.23 175.04 FALSE TRUE FALSE 163.211267 75.99399344 201.5735232 237.6625295 233.7786995 313.5481007 224.7230471 503.6896231 131.0792374 181.122627 0.901109208 0.419572058 1.112911879 1.312163662 1.290720566 1.731137108 1.24072321 2.780931524 0.723704374 1 7.500822978 -1 0.528617429 0.931243888 65.00350741 0.761020954 0.299379247 38.15308904 0.339106541 0.053441047 2765.314124 0.1 1 64.07226352 up SSGPYGGGGQYFAKPR ddPTM_HeLa_Curcumin_4h_R1 2 SSGPYGGGGQYFAKPR 16 1 F8W6I7;P09651-2;P09651;P09651-3;H0YH80 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 0 0 ; ; 187.63 3.18E-08 41884000 4233.1 2863.8 3402.8 3309.2 3627.2 5079.7 3887.6 3828.2 4580.8 4166.4 FALSE FALSE TRUE 3898.045668 3111.334111 3528.910761 3295.507407 3583.948009 4026.11296 3996.675593 4995.400557 4078.297701 4311.18209 0.904170964 0.721689329 0.818548298 0.764409236 0.83131446 0.933876806 0.927048663 1.158707856 0.945981315 1 12.07386778 -4.230117632 3.068179542 0.90423956 1.209508111 0.456801178 0.087971024 0.406409725 5.302399185 0.015177886 0.310465815 5.89E-05 4.230117632 0.305268551 SSGRNS(ph)PSAASTSSNDSK ddPTM_HeLa_Curcumin_4h_R1 4 SSGRNSPSAASTSSNDSK 18 1 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 0 S(0.006)S(0.006)GRNS(0.818)PS(0.17)AASTSSNDSK;S(0.011)S(0.011)GRNS(0.766)PS(0.211)AASTSSNDSK;S(0.136)S(0.136)GRNS(0.713)PS(0.015)AASTSSNDSK;S(0.027)S(0.027)GRNS(0.941)PS(0.004)AASTSSNDSK ;;; 141.36 0.00012229 66092200 5724.6 5850.85 5469.2 5110.99 6016.81 6233.69 4447.36 2407.84 5050.3 4639.7 TRUE FALSE FALSE 5271.491869 6356.571403 5671.893363 5089.842078 5945.06347 4940.752426 4572.140952 3141.979332 4496.294725 4800.92923 1.098014909 1.324029391 1.181415741 1.060178527 1.238315165 1.029124194 0.952345001 0.654452332 0.936546762 1 12.22909795 -4.273367417 1.79417499 1.091320867 0.517593999 0.616878441 0.10932637 0.469447312 1.5230029 0.016153874 0.451125655 5.33E-05 4.273367417 -0.573726868 SSGS(ph)ETEQVVDFSDR ddPTM_HeLa_Curcumin_4h_R1 1 SSGSETEQVVDFSDR 15 0 O95251-4;O95251;O95251-2 O95251-4 KAT7 Histone acetyltransferase KAT7 1 0 SSGS(0.5)ET(0.5)EQVVDFSDR 273.44 1.43E-51 37963000 1533.1 1227.9 1280 1400.2 1796.8 1698.6 1408 1619.7 1320.3 1412.7 TRUE FALSE FALSE 1411.753517 1334.034205 1327.437926 1394.406343 1775.374334 1346.291213 1447.504691 2113.539074 1175.466393 1461.79122 0.965769597 0.91260242 0.908089957 0.95390253 1.214519768 0.920987344 0.990226696 1.445855636 0.804127414 1 10.51352156 -4.261754145 7.203347891 0.983041434 1.451872677 0.670100899 0.100726862 0.039128066 16.96575229 0.011062227 0.08912566 5.47E-05 4.261754145 0.468831243 SSGS(ph)HSHSPSSHY(ph)RYR ddPTM_HeLa_Curcumin_4h_R1 2 SSGSHSHSPSSHYRYR 16 1 E5RJX3;H0YAZ8;H0YB53;E7EWW5;O43312-2;O43312-4;O43312;O43312-5 E5RJX3 MTSS1 Metastasis suppressor protein 1 2 0 SSGS(0.992)HS(0.035)HS(0.022)PS(0.015)S(0.204)HY(0.366)RY(0.366)R;SS(0.005)GS(0.976)HS(0.105)HS(0.064)PS(0.019)S(0.174)HY(0.328)RY(0.328)R ; 83.877 0.0042272 0 2677.3 2093.61 1850.69 2366.2 2831.5 3043.4 2353.3 1545.84 2614.4 2319.2 TRUE FALSE FALSE 2465.38888 2274.572319 1919.278199 2356.409291 2797.736212 2412.164534 2419.327264 2017.1595 2327.606861 2399.792027 1.027334391 0.9478206 0.799768554 0.981922293 1.165824446 1.005155658 1.008140388 0.840555964 0.969920241 1 11.22869367 SSGS(ph)PEPSPAIAK ddPTM_HeLa_Curcumin_4h_R1 2 SSGSPEPSPAIAK 13 0 Q66K64;K7ELE9 Q66K64 DCAF15 DDB1- and CUL4-associated factor 15 1 0 S(0.014)S(0.001)GS(0.985)PEPSPAIAK;S(0.049)SGS(0.951)PEPSPAIAK ; 175.21 0.00020171 130553000 14242.5 12261.6 11876 12581.5 11121 11601.2 7710.6 10315.6 14154 12504.7 TRUE FALSE FALSE 13115.1911 13321.43807 12316.13501 12529.44109 10988.38934 9194.980348 7926.938684 13460.77895 12601.34161 12939.23739 1.01359846 1.029538114 0.951843964 0.968329176 0.849230059 0.710627688 0.612627966 1.040306978 0.973885958 1 13.65946497 -5.703541426 2.483748081 1.003802719 0.770563965 0.443089792 0.103124712 0.160756321 2.017436694 0.014073243 0.030485921 1.98E-06 5.703541426 -0.233238754 SSGS(ph)PYGGGYGS(ph)GGGSGGYGSR ddPTM_HeLa_Curcumin_4h_R1 2 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 2 0 S(0.006)S(0.008)GS(0.987)PYGGGYGS(0.999)GGGS(0.001)GGYGSR;S(0.257)S(0.313)GS(0.423)PY(0.005)GGGY(0.002)GS(0.618)GGGS(0.379)GGYGS(0.004)R ; 178.73 1.41E-09 16544200 4148.6 3609.4 3918.9 4189.2 3849.13 7048.9 6947.1 2587.74 4486.2 4245.7 TRUE FALSE FALSE 3820.233932 3921.380453 4064.137881 4171.8662 3803.231639 5586.878683 7142.016929 3376.730014 3994.075084 4393.237759 0.869571405 0.892594635 0.925089445 0.94961084 0.8657013 1.271699596 1.625684136 0.768619911 0.909141572 1 12.10106886 -5.255631509 24.53185182 0.929203247 1.262369541 0.327883671 0.197648664 273.2547819 1154193.484 0.025165392 0.062262508 5.55E-06 5.255631509 0.333166295 SSGS(ph)PYGGGYGSGGGSGGYGSR ddPTM_HeLa_Curcumin_4h_R1 30 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 1 0 S(0.002)S(0.053)GS(0.945)PYGGGYGSGGGSGGYGSR;S(0.009)S(0.009)GS(0.983)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.002)GS(0.998)PYGGGYGSGGGSGGYGSR;S(0.03)S(0.004)GS(0.966)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;SS(0.01)GS(0.99)PYGGGYGSGGGSGGYGSR;SS(0.001)GS(0.999)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.004)GS(0.995)PYGGGYGSGGGSGGYGSR;S(0.006)S(0.02)GS(0.898)PY(0.007)GGGYGS(0.001)GGGS(0.01)GGYGS(0.058)R;SSGS(1)PYGGGYGSGGGSGGYGSR;SSGS(0.999)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR;S(0.054)S(0.054)GS(0.892)PYGGGYGSGGGSGGYGSR;SS(0.001)GS(0.999)PYGGGYGSGGGSGGYGSR;S(0.038)S(0.038)GS(0.878)PY(0.046)GGGYGSGGGSGGYGSR;S(0.107)S(0.063)GS(0.83)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.002)GS(0.997)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.001)GS(0.997)PY(0.001)GGGYGSGGGSGGYGSR;S(0.182)S(0.039)GS(0.779)PYGGGYGSGGGSGGYGSR;S(0.04)S(0.005)GS(0.472)PY(0.397)GGGY(0.055)GS(0.007)GGGS(0.023)GGY(0.001)GS(0.001)R;S(0.001)S(0.003)GS(0.996)PYGGGYGSGGGSGGYGSR;S(0.396)S(0.039)GS(0.565)PYGGGYGSGGGSGGYGSR;S(0.008)S(0.008)GS(0.964)PY(0.017)GGGY(0.003)GSGGGSGGYGSR;S(0.015)S(0.039)GS(0.946)PY(0.001)GGGYGSGGGSGGYGSR;S(0.01)S(0.026)GS(0.885)PY(0.01)GGGY(0.022)GS(0.009)GGGS(0.011)GGY(0.012)GS(0.014)R;S(0.006)S(0.006)GS(0.988)PYGGGYGSGGGSGGYGSR;S(0.006)S(0.024)GS(0.97)PYGGGYGSGGGSGGYGSR;S(0.001)S(0.001)GS(0.997)PYGGGYGSGGGSGGYGSR;SSGS(1)PYGGGYGSGGGSGGYGSR ;;;;;;;;;;;;;;;;;;;;;;;;;;;;; 369.77 1.06E-205 1942909600 56666.47 46911.31 49659.66 52826.59 52779.25 67689.58 52672.9 32520.64 58278.62 48101.33 TRUE FALSE FALSE 52181.25911 50966.1146 51500.09068 52608.00757 52149.89192 53649.99809 54150.75981 42436.03343 51885.60119 49772.84764 1.048388059 1.023974256 1.034702516 1.05696198 1.047757852 1.077896898 1.08795784 0.852594044 1.042447914 1 15.60307131 -4.250970922 24.80222711 1.035000543 0.852593929 0.826249057 0.026212639 520.6570622 1233531.541 0.004421825 0.084475723 5.61E-05 4.250970922 -0.182406614 SSGS(ph)SPAMETR ddPTM_HeLa_Curcumin_4h_R1 1 SSGSSPAMETR 11 0 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 0 SS(0.009)GS(0.617)S(0.373)PAMETR 138.2 0.0016166 6612900 3059.1 2834.1 2674.2 3226.4 2386.4 2615 2018.8 1098.4 2996.3 2814.9 TRUE FALSE FALSE 2816.969007 3079.066975 2773.308204 3213.050012 2357.943739 2072.619523 2075.442095 1433.297104 2667.613386 2912.717565 0.967127414 1.057111411 0.9521377 1.103110734 0.809533944 0.711575866 0.712544917 0.492082418 0.915850345 1 11.5081501 -5.123175039 1.195953438 0.995123462 0.55272802 0.832594138 0.073289458 0.146855842 0.354831839 0.010005057 0.054316597 7.53E-06 5.123175039 -0.442395442 SSGSEGSS(ph)PNWLQALK ddPTM_HeLa_Curcumin_4h_R1 1 SSGSEGSSPNWLQALK 16 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 SSGSEGS(0.064)S(0.935)PNWLQALK 111.81 0.001491 30162000 3633.6 3360.5 3006.8 3741.1 3224.4 5018.8 4246.4 2130.3 3744.2 2603.4 TRUE FALSE FALSE 3345.996726 3650.966646 3118.234653 3725.620319 3185.951136 3977.844306 4365.542555 2779.818663 3333.470628 2693.867956 1.242078966 1.3552879 1.157530623 1.383000347 1.182667892 1.476629282 1.620548084 1.031906058 1.23742911 1 11.39546342 -8.944968115 0.298104099 0.876797738 1.377598121 0.097721594 0.174455967 2.419183449 0.347951044 0.434498643 0.100390243 1.14E-09 8.944968115 0.500800383 SSGSET(ph)EQVVDFSDRET(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SSGSETEQVVDFSDRETK 18 1 O95251-4;O95251 O95251-4 KAT7 Histone acetyltransferase KAT7 2 0 S(0.083)S(0.096)GS(0.147)ET(0.654)EQVVDFS(0.164)DRET(0.856)K 66.075 0.010986 4356300 3053 2397.8 2546.3 2928 2361.5 3644.8 2750.4 3656 3304.3 2919 TRUE FALSE FALSE 2811.351828 2605.055148 2640.668118 2915.884712 2333.340655 2888.827395 2827.568822 4770.69757 2941.826557 3020.435033 0.930777123 0.862476802 0.874267478 0.965385675 0.772518074 0.956427589 0.936146214 1.579473658 0.973974452 1 11.56054064 -4.261331194 24.59396108 0.938112148 1.57947387 0.899533423 0.065932864 1.675445246 380241.0617 0.009901502 0.076499137 5.48E-05 4.261331194 0.641361722 SSGSETEQVVDFSDRET(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SSGSETEQVVDFSDRETK 18 1 O95251-4;O95251 O95251-4 KAT7 Histone acetyltransferase KAT7 1 0 SSGSETEQVVDFS(0.294)DRET(0.706)K 99.923 0.0011819 0 1463.6 1369.4 1474.4 1377.8 1679.3 2152.4 1301.3 949.63 1695.8 1804.3 TRUE FALSE FALSE 1347.754516 1487.764834 1529.042561 1372.099029 1659.275444 1705.967977 1337.810976 1239.167815 1509.774983 1866.999291 0.721882714 0.796874879 0.818984007 0.734922094 0.888739194 0.913748594 0.716556767 0.663721632 0.808663929 1 10.86650566 -9.387134929 1.033307019 1.004033119 0.782815117 0.092614684 0.093681452 0.353401745 0.655252885 0.058764618 0.014005574 4.10E-10 9.387134929 -0.221218002 SSGSPYGGGYGSGGGSGGYGSR ddPTM_HeLa_Curcumin_4h_R1 2 SSGSPYGGGYGSGGGSGGYGSR 22 0 P51991;P51991-2;H7C1J8 P51991 HNRNPA3 Heterogeneous nuclear ribonucleoprotein A3 0 0 ; ; 331.4 1.94E-181 7688900 405.19 350.14 720.74 414.48 380.39 746.56 505.53 353.61 577.09 634.44 FALSE FALSE TRUE 373.1187839 380.4045414 747.4512584 412.7649916 375.8540977 591.7150405 519.7138112 461.4240612 513.7846708 656.4867428 0.568356921 0.579455024 1.138562609 0.628748404 0.572523515 0.901335856 0.791659263 0.702868818 0.782627641 1 9.358622067 -9.558466498 1.351009422 0.998999061 0.71987244 0.054580649 0.181104654 0.474599176 1.56119101 0.119248623 0.028558589 2.76E-10 9.558466498 -0.279126621 SSGSSSSGLGTVSNS(ph)PASQR ddPTM_HeLa_Curcumin_4h_R1 3 SSGSSSSGLGTVSNSPASQR 20 0 H0Y589;H0Y3N9;Q9UPP1-5;Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1 H0Y589 PHF8 Histone lysine demethylase PHF8 1 0 SSGSSSSGLGTVSNS(0.999)PAS(0.001)QR;SSGSSSSGLGTVSNS(0.997)PAS(0.003)QR;SSGSSSSGLGTVSNS(0.999)PAS(0.001)QR ;; 345.81 1.65E-155 40998500 3818.98 4112.14 3947.04 3935.97 3723.46 4344.52 3657.93 1677.89 4268.91 3829.65 TRUE FALSE FALSE 3516.703703 4467.575058 4093.320775 3919.683999 3679.060171 3443.417579 3760.561671 2189.470937 3800.621253 3962.730052 0.88744468 1.127398283 1.032954736 0.989137273 0.928415542 0.868950833 0.94898255 0.552515793 0.959091637 1 11.95227898 -3.922728795 1.722570229 0.964131802 5.15E-15 0.751313985 0.071783142 1.165721621 1.57642059 0.011373273 2.455811635 0.000119473 3.922728795 -0.964131802 SSGSSSSGLGTVSNSPAS(ph)QR ddPTM_HeLa_Curcumin_4h_R1 1 SSGSSSSGLGTVSNSPASQR 20 0 H0Y589;H0Y3N9;Q9UPP1-5;Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1 H0Y589 PHF8 Histone lysine demethylase PHF8 1 0 SSGSSSSGLGTVSNS(0.232)PAS(0.768)QR 329.64 1.91E-134 26855000 2054.6 2401.4 2114.2 1728.1 1582.2 2387.6 2183.9 768.44 2664.5 2489.5 TRUE FALSE FALSE 1891.976242 2608.966316 2192.554112 1720.94958 1563.333298 1892.384846 2245.174356 1002.733819 2372.211016 2576.00994 0.734459993 1.012793575 0.851143498 0.668067911 0.606881703 0.734618612 0.871570533 0.389258521 0.920885816 1 11.33092244 -6.29570711 4.825182119 0.883280056 0.667327894 0.458469561 0.134727435 0.181158949 10.74281449 0.022602292 0.035574284 5.06E-07 6.29570711 -0.215952163 SSGT(ph)ASSVAFT(ph)PLQGLEIVNPQAAEK ddPTM_HeLa_Curcumin_4h_R1 1 SSGTASSVAFTPLQGLEIVNPQAAEK 26 0 E7EVX8;Q8WWY3 E7EVX8 PRPF31 U4/U6 small nuclear ribonucleoprotein Prp31 2 0 S(0.211)S(0.239)GT(0.24)AS(0.24)S(0.079)VAFT(0.992)PLQGLEIVNPQAAEK 62.487 0.0041921 24297000 2107.6 1982 2137.4 2479.2 2292.7 3272.3 2131.8 2496.9 1760.8 3190.7 TRUE FALSE FALSE 1940.781236 2153.315248 2216.613924 2468.941727 2265.36105 2593.588094 2191.612571 3258.193316 1567.644645 3301.576588 0.587834686 0.652208177 0.671380435 0.747806892 0.686145237 0.785560481 0.663807885 0.986859832 0.474816986 1 11.6889394 -9.462927685 1.205727954 0.999616781 0.705416151 0 0.19185901 0.295551476 0.77019963 0.071595296 0.017778958 3.44E-10 9.462927685 -0.29420063 SSGTAS(ph)SVAFT(ph)PLQGLEIVNPQAAEKK ddPTM_HeLa_Curcumin_4h_R1 1 SSGTASSVAFTPLQGLEIVNPQAAEKK 27 1 E7EVX8;Q8WWY3 E7EVX8 PRPF31 U4/U6 small nuclear ribonucleoprotein Prp31 2 0 S(0.185)S(0.229)GT(0.255)AS(0.285)S(0.08)VAFT(0.966)PLQGLEIVNPQAAEKK 83.054 3.29E-05 17037000 1244.8 1221.3 1455.1 1321.4 949.82 1639.8 1239.5 1271.5 1287 1740.6 TRUE FALSE FALSE 1146.272766 1326.86373 1509.027286 1315.932397 938.4940168 1299.686996 1274.277034 1659.174497 1145.81932 1801.08572 0.63643432 0.736702154 0.837843124 0.730632852 0.521071266 0.72161307 0.707504934 0.921207957 0.636182558 1 10.81465113 -9.392557537 1.023910807 1.00634455 0.716336243 0 0.150330403 0.362491801 0.655787081 0.078927967 0.018489162 4.05E-10 9.392557537 -0.290008307 SSGTAS(ph)SVAFTPLQGLEIVNPQAAEKK ddPTM_HeLa_Curcumin_4h_R1 2 SSGTASSVAFTPLQGLEIVNPQAAEKK 27 1 E7EVX8;Q8WWY3 E7EVX8 PRPF31 U4/U6 small nuclear ribonucleoprotein Prp31 1 0 S(0.092)S(0.107)GT(0.124)AS(0.553)S(0.124)VAFTPLQGLEIVNPQAAEKK;S(0.307)S(0.085)GT(0.031)AS(0.45)S(0.127)VAFTPLQGLEIVNPQAAEKK ; 112.06 1.85E-08 44025000 3198.4 2974.5 3419.1 4585.6 3079.9 4634.6 3090.6 3436.5 3478.3 4430 TRUE FALSE FALSE 2945.243265 3231.602526 3545.814854 4566.626002 3043.174204 3673.331717 3177.313918 4484.27303 3096.739192 4583.94217 0.642513181 0.704983267 0.773529578 0.996222429 0.663877093 0.801347744 0.693140053 0.978256894 0.675562448 1 12.16237313 -9.537940335 1.319691398 0.999159198 0.763070746 0 0.152546686 0.384735654 1.206853173 0.08020805 0.019393201 2.90E-10 9.537940335 -0.236088451 SSGTASS(ph)VAFT(ph)PLQGLEIVNPQAAEKK ddPTM_HeLa_Curcumin_4h_R1 1 SSGTASSVAFTPLQGLEIVNPQAAEKK 27 1 E7EVX8;Q8WWY3 E7EVX8 PRPF31 U4/U6 small nuclear ribonucleoprotein Prp31 2 0 S(0.073)S(0.077)GT(0.099)AS(0.394)S(0.472)VAFT(0.884)PLQGLEIVNPQAAEKK 71.903 0.00026138 17825000 1439 1393.5 1889.4 1844.8 1289.9 2025 1208.1 1641.7 1832.2 2165.2 TRUE FALSE FALSE 1325.101632 1513.947931 1959.422826 1837.166706 1274.518785 1604.992174 1241.996035 2142.246773 1631.212244 2240.440539 0.591446909 0.675736715 0.874570332 0.820002439 0.568869721 0.716373475 0.554353491 0.956172117 0.728076562 1 11.12956672 -9.455805697 1.164734041 1.001602644 0.704019571 0.006582921 0.150748026 0.368927094 0.887633526 0.08902481 0.021585203 3.50E-10 9.455805697 -0.297583073 SSGTASSVAFT(ph)PLQGLEIVNPQAAEKK ddPTM_HeLa_Curcumin_4h_R1 2 SSGTASSVAFTPLQGLEIVNPQAAEKK 27 1 E7EVX8;Q8WWY3 E7EVX8 PRPF31 U4/U6 small nuclear ribonucleoprotein Prp31 1 0 S(0.001)S(0.001)GT(0.001)AS(0.001)S(0.002)VAFT(0.995)PLQGLEIVNPQAAEKK;SSGTASS(0.001)VAFT(0.998)PLQGLEIVNPQAAEKK ; 94.955 2.23E-06 36709000 2325.19 1843.3 2419.65 2500.9 2070.96 2767.3 2236.73 2099.59 2723.4 2140.9 TRUE FALSE FALSE 2141.148758 2002.626638 2509.324358 2490.551938 2046.265155 2193.330786 2299.486624 2739.745326 2424.649834 2215.296116 0.96652937 0.903999526 1.132726384 1.124252384 0.923698254 0.990084698 1.038004178 1.236740003 1.094503717 1 11.11328384 -6.759339653 24.99964781 0.977738183 1.064207139 0.153666218 0.091479078 70.09589908 834565.2779 0.013443973 0.018481484 1.74E-07 6.759339653 0.086468956 LIIESPS(ph)NTSSTEPA ddPTM_HeLa_Curcumin_4h_R1 2 LIIESPSNTSSTEPA 15 0 P38432 P38432 COIL Coilin 1 0 LIIES(0.393)PS(0.607)NTSSTEPA;LIIES(0.26)PS(0.74)NTSSTEPA ; 201.04 2.59E-09 23968000 9781.9 8185 9071.5 9163.7 8743.3 10569.9 7134.5 2394.63 10737.8 8341.4 TRUE FALSE FALSE 9007.652293 8892.474928 9407.69777 9125.783037 8639.041858 8377.583593 7334.674868 3124.741663 9559.890205 8631.263029 1.043607669 1.030263462 1.089956098 1.057294049 1.000901239 0.970609233 0.84978002 0.362026004 1.107588793 1 13.07535597 -4.157937872 1.615312247 1.027849999 2.91E-18 0.967868517 0.037274072 0.138562607 0.278775288 0.004611719 0.239971218 6.95E-05 4.157937872 -1.027849999 down SSHYDELLAAEAR ddPTM_HeLa_Curcumin_4h_R1 1 SSHYDELLAAEAR 13 0 Q7KZF4;H7C597 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 0 169.09 0.00015279 10765000 2170.1 1870 1897.8 1609.8 2190.8 3663.3 1944.5 1581.7 2566.9 1973.5 FALSE FALSE TRUE 1998.334295 2031.634467 1968.134137 1603.139074 2164.676141 2903.490286 1999.057437 2063.953049 2285.317492 2042.078978 0.978578359 0.994885354 0.963789432 0.785052435 1.060035466 1.421830555 0.978932479 1.010711667 1.119113177 1 10.99582295 -5.5240798 24.99999252 0.972987094 1.141268555 0.231931826 0.134205252 38.40605418 799427.2723 0.017714449 0.035661953 2.99E-06 5.5240798 0.16828146 SSILLDVKPWDDETDMAK ddPTM_HeLa_Curcumin_4h_R1 1 SSILLDVKPWDDETDMAK 18 1 P24534 P24534 EEF1B2 Elongation factor 1-beta 0 0 106.82 0.00080331 23901000 1119.5 888.53 872.07 886.11 1094.2 985.4 940.28 1032.7 958.18 1005.4 FALSE FALSE TRUE 1030.890394 965.330574 904.3896814 882.4435116 1081.15238 781.0169323 966.6617262 1347.565476 853.0700512 1040.337575 0.990919119 0.927901286 0.869323288 0.848228049 1.03923227 0.750734138 0.929180825 1.295315586 0.819993502 1 10.02283602 -7.301139536 7.096915256 0.995814009 0.939103928 0 0.14720693 0.708110579 105.5884564 0.022325026 0.025613489 5.00E-08 7.301139536 -0.056710081 GAASTLVPGVSET(ph)SASPGSPSVR ddPTM_HeLa_Curcumin_4h_R1 1 GAASTLVPGVSETSASPGSPSVR 23 0 A0A0A0MS59;A0A0C4DFX4;Q6ZRS2-3;Q6ZRS2-2;Q6ZRS2 A0A0A0MS59 SRCAP Helicase SRCAP 1 0 GAASTLVPGVS(0.007)ET(0.723)S(0.104)AS(0.156)PGS(0.009)PS(0.001)VR 172.99 8.47E-09 18109000 7723.5 5989.6 6460 7279 6458 7516.4 5310.7 1929.6 7995 6774.1 TRUE FALSE FALSE 7112.176825 6507.314335 6699.413283 7248.881427 6380.992568 5957.413913 5459.703949 2517.926157 7117.968503 7009.499471 1.014648315 0.928356491 0.955762007 1.034151077 0.910334981 0.849905751 0.778900686 0.359216256 1.015474576 1 12.77509571 -4.157510572 1.051511572 0.995561476 6.19E-22 0.945341352 0.044712869 0.323510324 0.242987385 0.006651877 0.377792068 6.96E-05 4.157510572 -0.995561476 down SSISGS(ph)LPSSGSLQAVSSR ddPTM_HeLa_Curcumin_4h_R1 1 SSISGSLPSSGSLQAVSSR 19 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 0 S(0.002)S(0.057)IS(0.023)GS(0.399)LPS(0.399)S(0.119)GS(0.001)LQAVSSR 215.64 2.75E-18 9466700 1771.6 1687.8 1789.7 1729.3 1455.5 1649.5 1085.6 1228.9 1890.2 1498.7 TRUE FALSE FALSE 1631.375991 1833.685911 1856.027856 1722.144615 1438.144113 1307.375106 1116.059014 1603.585953 1682.849789 1550.779713 1.051971454 1.182428359 1.19683527 1.110502414 0.927368407 0.843043725 0.719676047 1.034051412 1.08516366 1 10.59877805 -5.577245182 4.294689281 1.057723734 0.854692909 0.540079576 0.096281459 0.146292923 5.625147134 0.015065776 0.031567024 2.65E-06 5.577245182 -0.203030824 ESSKELESPLT(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 3 ESSKELESPLTPGK 14 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 0 ESSKELES(0.024)PLT(0.976)PGK;ESSKELES(0.01)PLT(0.99)PGK;ESSKELES(0.008)PLT(0.992)PGK ;; 88.637 0.0091857 45737000 21280.2 17577 18109.1 21038.1 20410.8 21229.7 17462.4 4622.2 20177 18851.3 TRUE FALSE FALSE 19595.84972 19096.27756 18780.23918 20951.04992 20167.41454 16826.42091 17952.34795 6031.487502 17963.63358 19506.38127 1.004586624 0.97897592 0.962774126 1.074061335 1.033888052 0.862611095 0.920332054 0.309205865 0.920910615 1 14.25165854 -4.15704838 2.070259088 0.998667986 1.38E-18 0.921179457 0.058229211 0.163056039 0.597580674 0.007062533 0.334028462 6.97E-05 4.15704838 -0.998667986 down SSKAS(ph)LGS(ph)LEGEAEAEASSPK ddPTM_HeLa_Curcumin_4h_R1 2 SSKASLGSLEGEAEAEASSPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 S(0.373)S(0.398)KAS(0.407)LGS(0.821)LEGEAEAEASSPK;S(0.329)S(0.361)KAS(0.466)LGS(0.798)LEGEAEAEAS(0.034)S(0.012)PK ; 71.149 0.0021503 57568000 7043.2 5641.1 4983.9 5315.7 4806.3 6025.9 5403.5 5389.1 7008.6 5141.4 TRUE FALSE FALSE 6485.723288 6128.691548 5168.607718 5293.705042 4748.988012 4776.060414 5555.107667 7032.211782 6239.774115 5320.063267 1.219106421 1.151995989 0.97153125 0.995045505 0.892656304 0.897745041 1.044180753 1.3218286 1.172875923 1 12.37722769 -6.759887823 24.98110998 1.109997589 1.009026815 0.154296002 0.125031858 73.27831087 1179819.071 0.022293775 0.030579682 1.74E-07 6.759887823 -0.100970774 SSKASLGS(ph)LEGEAEAEASSPK ddPTM_HeLa_Curcumin_4h_R1 1 SSKASLGSLEGEAEAEASSPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 S(0.208)S(0.208)KAS(0.178)LGS(0.407)LEGEAEAEASSPK 69.47 0.0014578 9895400 3140.5 2424.3 2448.8 3181.9 2633.2 2920.8 2349.5 5155.9 3243.8 2553.1 TRUE FALSE FALSE 2891.926111 2633.84569 2539.554682 3168.734141 2601.80081 2314.993156 2415.420647 6727.910175 2887.963256 2641.820035 1.094671883 0.996981496 0.961289811 1.199451173 0.984851646 0.876287228 0.914301737 2.546695114 1.093171835 1 11.36731648 -4.258898182 24.9999034 1.025374065 2.546695651 0.962902476 0.090257651 30.73929898 302390.1872 0.012677234 0.11581145 5.51E-05 4.258898182 1.521321585 SSLEPDS(ph)EEDDRK ddPTM_HeLa_Curcumin_4h_R1 1 SSLEPDSEEDDRK 13 1 A0A1B0GV45 A0A1B0GV45 1 0 SSLEPDS(1)EEDDRK 82.837 0.0090757 15027000 1536.6 1445.7 1581.1 1816.8 2008.9 2130.7 1523.9 1359.6 1636.5 1444 TRUE FALSE FALSE 1414.976489 1570.659866 1639.696957 1809.282563 1984.94518 1688.768802 1566.656533 1774.135781 1456.980044 1494.178893 0.94699269 1.051185955 1.097389988 1.210887513 1.328452162 1.130232003 1.048506668 1.18736504 0.975104154 1 10.54513717 -6.758082796 2.09396154 0.975744152 1.177056387 0.631284965 0.068437501 0.154214665 1.386644297 0.012334666 0.017645213 1.75E-07 6.758082796 0.201312235 SSLET(ph)LEDIEENAPLRR ddPTM_HeLa_Curcumin_4h_R1 1 SSLETLEDIEENAPLRR 17 1 V9GYB4;Q8TDN4-2;Q8TDN4 V9GYB4 CABLES1 CDK5 and ABL1 enzyme substrate 1 1 0 S(0.324)S(0.085)LET(0.59)LEDIEENAPLRR 68.525 0.011107 1661900 224.93 0 76.451 137.62 197.57 137.77 203.95 167.02 225.01 166.65 TRUE FALSE FALSE 207.1265532 0 79.28434131 137.0505649 195.2141068 109.194949 209.6722881 217.9436291 200.3269659 172.4410751 1.201143945 0 0.459776427 0.794767516 1.132062687 0.633230505 1.215906871 1.263873059 1.161712578 1 7.429959652 SSLGPVGLDK ddPTM_HeLa_Curcumin_4h_R1 1 SSLGPVGLDK 10 0 P17987;E7ERF2;F5GYL4;F5H726;F5GZI8;F5H676;F5H136 P17987 TCP1 T-complex protein 1 subunit alpha 0 0 123.75 0.0023751 5666700 2983.7 2794.5 2954.5 3053.7 3135.2 3282.2 2768.2 2979.4 3404.8 3304.7 FALSE FALSE TRUE 2747.536997 3036.044128 3063.996369 3041.064599 3097.814788 2601.434722 2845.868242 3887.805345 3031.301958 3419.538079 0.803481913 0.887852119 0.896026393 0.889320291 0.905916155 0.760756179 0.832237623 1.136938749 0.886465332 1 11.73958574 -9.565641048 1.354107065 0.999722306 0.873244286 0 0.101167887 0.561908011 1.85312247 0.06428915 0.015251138 2.72E-10 9.565641048 -0.12647802 SSLGQS(ph)AS(ph)ETEEDTVSVSKK ddPTM_HeLa_Curcumin_4h_R1 2 SSLGQSASETEEDTVSVSKK 20 1 E9PPJ0;Q13435;H0YCG1;E9PJ04 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 2 0 S(0.019)S(0.021)LGQS(0.778)AS(0.596)ET(0.53)EEDT(0.045)VS(0.008)VS(0.002)KK;S(0.001)S(0.002)LGQS(0.986)AS(0.95)ET(0.061)EEDTVSVSKK ; 106.11 0.00013407 27528400 9209.1 7446.5 7947 8123.6 7178.5 9460.6 5536.3 4187.3 9920.4 7988.5 TRUE FALSE FALSE 8480.190018 8090.142279 8241.522811 8089.986696 7092.901076 7498.364917 5691.633678 5463.988494 8832.15694 8266.09978 1.025899789 0.978713359 0.997026776 0.978694537 0.858071069 0.907122478 0.688551291 0.661011679 1.068479352 1 13.01299106 -4.623474957 0.694920245 1.011714311 0.505705555 0.908634343 0.040213861 0.325520987 0.145593271 0.005688247 0.116864413 2.38E-05 4.623474957 -0.506008756 SSLGQS(ph)ASET(ph)EEDTVSVSK ddPTM_HeLa_Curcumin_4h_R1 3 SSLGQSASETEEDTVSVSK 19 0 E9PPJ0;Q13435;H0YCG1;E9PJ04 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 2 0 S(0.049)S(0.06)LGQS(0.885)AS(0.046)ET(0.957)EEDT(0.004)VSVSK;SSLGQS(0.997)AS(0.044)ET(0.954)EEDT(0.005)VSVSK;S(0.164)S(0.19)LGQS(0.54)AS(0.201)ET(0.852)EEDT(0.05)VS(0.003)VSK ;; 141.97 1.29E-06 30746900 14042 12019.3 13324 14508.9 14309.4 14787.9 9521.6 6105.36 13511.9 11422.5 TRUE FALSE FALSE 12930.56088 13058.19474 13817.79916 14448.86602 14138.76975 11720.72285 9788.75047 7966.856158 12029.67838 11819.43102 1.094008743 1.104807389 1.169074817 1.222467138 1.196230996 0.991648652 0.828191344 0.67404735 1.01778828 1 13.52887297 -4.672984501 2.261562134 1.082154722 0.686797597 0.792273004 0.074006295 0.141137976 1.318077138 0.012888449 0.07881084 2.12E-05 4.672984501 -0.395357125 SSLGQS(ph)ASET(ph)EEDTVSVSKK ddPTM_HeLa_Curcumin_4h_R1 1 SSLGQSASETEEDTVSVSKK 20 1 E9PPJ0;Q13435;H0YCG1;E9PJ04 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 2 0 S(0.024)S(0.024)LGQS(0.919)AS(0.403)ET(0.555)EEDT(0.073)VS(0.002)VSKK 67.928 0.003135 0 2175.9 1722.3 1530.3 1698.1 1821.5 1838.8 1312.6 764.72 1821 1872.7 TRUE FALSE FALSE 2003.675219 1871.167938 1587.014264 1691.073712 1799.779802 1457.412152 1349.428023 997.8796077 1621.240856 1937.776186 1.034007557 0.965626449 0.818987392 0.872687839 0.928786211 0.752105513 0.696379713 0.51496123 0.836650212 1 10.92018623 -3.824999061 0.402047606 1.019214661 5.39E-19 0.729289816 0.077590193 1.689582891 0.144058929 0.015022046 0.888871608 0.000149624 3.824999061 -1.019214661 SSLGQS(ph)ASETEEDTVSVSK ddPTM_HeLa_Curcumin_4h_R1 1 SSLGQSASETEEDTVSVSK 19 0 E9PPJ0;Q13435;H0YCG1;E9PJ04 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 0 S(0.001)S(0.001)LGQS(0.968)AS(0.029)ETEEDT(0.001)VSVSK 104.95 0.001932 0 2292.5 2625.1 2597.8 2538 2170.4 2773.6 2305.9 1895.3 2504 3593 TRUE FALSE FALSE 2111.046206 2852.001947 2694.076753 2527.498428 2144.519398 2198.324095 2370.597348 2473.168245 2229.317465 3717.856483 0.567812721 0.767109209 0.724631724 0.679826787 0.576816079 0.591288046 0.63762476 0.665213479 0.599624401 1 11.86025536 -9.392564747 0.869244363 1.024391982 0.646037056 0 0.137243138 0.242624428 0.292619331 0.064124019 0.012740385 4.05E-10 9.392564747 -0.378354927 SSLGQS(ph)ASETEEDTVSVSKK ddPTM_HeLa_Curcumin_4h_R1 3 SSLGQSASETEEDTVSVSKK 20 1 E9PPJ0;Q13435;H0YCG1;E9PJ04 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 0 S(0.002)S(0.002)LGQS(0.332)AS(0.332)ET(0.332)EEDT(0.001)VSVSKK;S(0.001)S(0.001)LGQS(0.677)AS(0.218)ET(0.102)EEDTVSVSKK;S(0.012)S(0.003)LGQS(0.887)AS(0.062)ET(0.035)EEDTVSVSKK ;; 137.86 5.55E-05 111811000 7762.6 5148.8 5676.3 6580.2 6159.4 7209.6 5323.3 4184.73 7206.1 6413.4 TRUE FALSE FALSE 7148.182019 5593.839329 5886.668671 6552.972876 6085.953178 5714.247691 5472.657471 5460.634913 6415.608859 6636.265173 1.077139299 0.842919803 0.887045427 0.98744892 0.917075044 0.861063798 0.824659252 0.822847606 0.966749925 1 12.69615582 -6.130450643 0.516672046 1.03552786 0.814885838 0.39880833 0.063394596 0.626059216 0.304581051 0.018700283 0.061237527 7.41E-07 6.130450643 -0.220642022 SSLGQSAS(ph)ETEEDTVSVSK ddPTM_HeLa_Curcumin_4h_R1 3 SSLGQSASETEEDTVSVSK 19 0 E9PPJ0;Q13435;H0YCG1;E9PJ04 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 0 SSLGQS(0.002)AS(0.997)ET(0.001)EEDTVSVSK;S(0.009)S(0.011)LGQS(0.241)AS(0.709)ET(0.03)EEDTVSVSK;SSLGQS(0.016)AS(0.873)ET(0.001)EEDT(0.097)VS(0.012)VSK ;; 289.68 6.25E-83 53907000 7458.5 6226.9 6981.7 6858.5 7957.6 8362.1 6215.2 5467.6 6926 6054.5 TRUE FALSE FALSE 6868.151855 6765.125489 7240.447944 6830.121344 7862.710817 6627.7062 6389.581785 7134.64607 6166.235128 6264.893424 1.09629189 1.07984686 1.155717656 1.090221474 1.255043029 1.057912043 1.019902711 1.1388296 0.984252199 1 12.61307425 -8.80178605 0.610129559 0.995603261 1.11467482 0.385036269 0.060369159 0.790724272 0.541200087 0.048047672 0.014653118 1.58E-09 8.80178605 0.119071559 SSLGQSAS(ph)ETEEDTVSVSKK ddPTM_HeLa_Curcumin_4h_R1 3 SSLGQSASETEEDTVSVSKK 20 1 E9PPJ0;Q13435;H0YCG1;E9PJ04 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 0 SSLGQS(0.191)AS(0.575)ET(0.233)EEDTVSVSKK;SSLGQS(0.073)AS(0.492)ET(0.435)EEDTVSVSKK;S(0.002)S(0.002)LGQS(0.095)AS(0.856)ET(0.046)EEDTVSVSKK ;; 100.44 0.00024964 496665000 6236.9 6095.5 5422.9 6049.6 5594.7 7264 5268.4 4858.8 7611.3 6531.1 TRUE FALSE FALSE 5743.242784 6622.367859 5623.877444 6024.568358 5527.986857 5757.364518 5416.217125 6340.225753 6776.359433 6758.055239 0.849836614 0.979922126 0.832173938 0.891464799 0.817984858 0.851926229 0.801446116 0.938173118 1.0027085 1 12.72239243 -11.15238536 0.306628528 1.235173022 0.853789088 0.517493731 0.051146281 7.10534396 0.339700736 1.109711491 0.021701748 7.04E-12 11.15238536 -0.381383935 SSLGQSASETEEDT(ph)VSVSK ddPTM_HeLa_Curcumin_4h_R1 2 SSLGQSASETEEDTVSVSK 19 0 E9PPJ0;Q13435;H0YCG1;E9PJ04 E9PPJ0 SF3B2 Splicing factor 3B subunit 2 1 0 SSLGQS(0.452)AS(0.094)ETEEDT(0.454)VSVSK;SSLGQSAS(0.018)ETEEDT(0.972)VS(0.01)VSK ; 221.81 2.81E-18 91893000 4727.2 3964.7 4334.7 4667.3 4846.9 5727.4 4253.3 3571.4 4356 3828.6 TRUE FALSE FALSE 4353.037132 4307.391002 4495.347795 4647.987949 4789.103883 4539.472679 4372.636151 4660.303419 3878.157698 3961.643565 1.098795755 1.087273737 1.134717882 1.173247384 1.208867937 1.145855907 1.103742949 1.176356061 0.978926457 1 11.95188337 -8.157961578 0.420330099 0.991409742 1.164023511 0.809185649 0.030897388 0.390885097 0.163925645 0.028121321 0.013990746 6.95E-09 8.157961578 0.172613769 SSLGS(ph)LQTPEAVTTR ddPTM_HeLa_Curcumin_4h_R1 1 SSLGSLQTPEAVTTR 15 0 Q7Z2W4-2;Q7Z2W4;C9J6P4;Q7Z2W4-3 Q7Z2W4-2 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 0 SSLGS(0.609)LQT(0.39)PEAVT(0.001)TR 115.04 0.0016983 26529000 2010.5 1614.3 1594.7 1659 1777.1 2971.5 2531.6 1016.2 2259 1477 TRUE FALSE FALSE 1851.366804 1753.832899 1653.800985 1652.135498 1755.909243 2355.177404 2602.629883 1326.034702 2011.193352 1528.32564 1.211369328 1.147551839 1.082099876 1.081010129 1.148910414 1.541018054 1.702928888 0.867638851 1.315945568 1 10.57773626 -5.385006922 5.987552083 1.104026278 1.402182831 0.176141902 0.21588679 0.210099227 9.408842432 0.028112932 0.063510537 4.12E-06 5.385006922 0.298156553 SSLGSLQT(ph)PEAVTTR ddPTM_HeLa_Curcumin_4h_R1 1 SSLGSLQTPEAVTTR 15 0 Q7Z2W4-2;Q7Z2W4;C9J6P4;Q7Z2W4-3 Q7Z2W4-2 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 0 SSLGS(0.011)LQT(0.543)PEAVT(0.223)T(0.223)R 104.41 0.0081735 10437000 1236.2 1110.6 1017 1140 821.55 1594.5 1755.6 519.17 1146 904.32 TRUE FALSE FALSE 1138.353466 1206.595315 1054.690915 1135.282982 811.7535528 1263.782726 1804.857411 677.462543 1020.286667 935.7450527 1.216520955 1.289448779 1.127113535 1.213239631 0.867494357 1.350563086 1.928791828 0.723981966 1.090346846 1 9.869971705 -13.52287874 0.156751922 0.092873546 1.309034721 0.036161671 0.303080254 125.1664912 1.318537444 34.77062963 0.597091116 3.00E-14 13.52287874 1.216161174 SSLQQGFLKNQIFTGIQMT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SSLQQGFLKNQIFTGIQMTR 20 1 K7EIE6 K7EIE6 ZNF562 1 0 SSLQQGFLKNQIFT(0.003)GIQMT(0.997)R 52.731 0.016559 73304000 714.97 465.19 757.8 583.77 865.47 970.51 573.95 525.8 874.14 771.53 TRUE FALSE FALSE 658.3793701 505.3989508 785.8847346 581.3545144 855.1498355 769.2152861 590.0534923 686.1139995 778.249029 798.3406101 0.824684805 0.633061809 0.984397793 0.72820361 1.071159133 0.963517672 0.739099934 0.859425151 0.974833322 1 9.64086059 -9.236167779 1.075030319 0.996433575 0.850954364 0.160305312 0.124676987 0.697097097 1.495503923 0.072108877 0.02195093 5.81E-10 9.236167779 -0.145479211 SSLS(ph)GDEEDELFK ddPTM_HeLa_Curcumin_4h_R1 1 SSLSGDEEDELFK 13 0 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 0 S(0.329)S(0.006)LS(0.665)GDEEDELFK 164.92 0.00017661 6124900 2155.2 1776.3 1847 2232 2370.7 1477.6 1179.1 1051 2355.3 1919.7 TRUE FALSE FALSE 1984.613646 1929.835457 1915.451445 2222.764575 2342.430951 1171.129104 1212.182373 1371.445062 2096.929483 1986.409432 0.999095964 0.971519479 0.964278267 1.118986116 1.179228669 0.589570853 0.610237926 0.690414091 1.055638102 1 10.9559473 -5.249625342 24.99997083 1.014241323 0.628090618 0.874217381 0.070955191 197.4438453 417814.8146 0.010184269 0.025736853 5.63E-06 5.249625342 -0.386150705 SSLS(ph)GDEEDELFKGATLK ddPTM_HeLa_Curcumin_4h_R1 2 SSLSGDEEDELFKGATLK 18 1 Q5T1M5;Q5T1M5-2 Q5T1M5 FKBP15 FK506-binding protein 15 1 0 S(0.089)S(0.121)LS(0.79)GDEEDELFKGATLK;S(0.302)S(0.095)LS(0.604)GDEEDELFKGATLK ; 144.75 9.22E-05 45782000 6801 4463.3 3926.7 5135.9 3071.6 6072.3 3218.7 3209.1 9248.5 7279.6 TRUE FALSE FALSE 6262.693674 4849.087764 4072.226956 5114.649007 3034.973176 4812.836531 3309.008059 4187.539817 8233.962689 7532.565558 0.831415754 0.643749826 0.540616198 0.679004911 0.402913609 0.638937224 0.439293629 0.555924776 1.093115304 1 12.87892561 -7.360668252 0.683522477 0.972391003 0.511970925 0.831597018 0.088820909 0.152761983 0.153404578 0.02149894 0.023870328 4.36E-08 7.360668252 -0.460420078 SSLS(ph)NNSLK ddPTM_HeLa_Curcumin_4h_R1 1 SSLSNNSLK 9 0 Q9ULJ7-2;Q9ULJ7 Q9ULJ7-2 ANKRD50 Ankyrin repeat domain-containing protein 50 1 0 S(0.324)S(0.066)LS(0.399)NNS(0.211)LK 100.88 0.012615 13928000 3250.8 3084.2 2915.5 3039.3 3216.1 3785.5 3047.2 1860.2 3173 2596.9 TRUE FALSE FALSE 2993.49575 3350.784505 3023.550995 3026.724182 3177.750108 3000.344629 3132.696231 2427.366417 2824.929838 2687.142082 1.114007246 1.246969607 1.125192082 1.126372961 1.182576139 1.116556005 1.165809673 0.903326413 1.051276692 1 11.39185689 -8.789117174 0.935279959 1.007790032 1.12808655 0.162548492 0.084618907 0.53309762 0.922326781 0.036378803 0.015895022 1.63E-09 8.789117174 0.120296518 SSLSNNECGS(ph)LDKTSPEMSNSNNDER ddPTM_HeLa_Curcumin_4h_R1 1 SSLSNNECGSLDKTSPEMSNSNNDER 26 1 Q5UIP0-2;Q5UIP0 Q5UIP0-2 RIF1 Telomere-associated protein RIF1 1 0 SSLS(0.014)NNECGS(0.535)LDKT(0.269)S(0.112)PEMS(0.065)NS(0.004)NNDER 62.678 0.0011909 17130000 1259.9 1385.9 1275.4 1270.2 1243.4 1144.7 996.64 904.65 1454.5 1318.4 TRUE FALSE FALSE 1160.177586 1505.691021 1322.667446 1264.944249 1228.573267 907.2763166 1024.603036 1180.473621 1294.944989 1364.214302 0.850436463 1.103705641 0.969545213 0.927232801 0.900572048 0.665054101 0.751057246 0.865313917 0.949224024 1 10.41385458 -5.436492259 5.47216442 0.944429709 0.760260749 0.583151413 0.076531618 0.147578974 7.162784279 0.012439389 0.028091146 3.66E-06 5.436492259 -0.18416896 SSPEPVALTES(ph)ETEYVIR ddPTM_HeLa_Curcumin_4h_R1 1 SSPEPVALTESETEYVIR 18 0 Q9Y678 Q9Y678 COPG1 Coatomer subunit gamma-1 1 0 SSPEPVALT(0.004)ES(0.941)ET(0.055)EYVIR 180.78 6.77E-07 3650200 377.58 400.46 393.93 422.11 360.12 421.3 402.01 392.21 353.45 393.18 TRUE FALSE FALSE 347.6941446 435.073978 408.5293923 420.3634207 355.8258042 333.917631 413.2893186 511.7930235 314.6774193 406.8429757 0.854615086 1.069390413 1.004145129 1.033232588 0.874602305 0.820753094 1.015844793 1.257962049 0.773461601 1 8.668328272 -7.258116415 24.88576457 0.931346014 0.999091113 0.152066006 0.125003374 649.7635248 4866102.005 0.020695767 0.024775158 5.52E-08 7.258116415 0.067745099 SSPETGTTGDVAWQIS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SSPETGTTGDVAWQISPK 18 0 E9PDC2;A0A088AWP5;Q8WUY3-4;Q8WUY3;Q8WUY3-2;Q8WUY3-3;H7BZH9 E9PDC2 PRUNE2 Protein prune homolog 2 1 0 SSPETGTTGDVAWQIS(1)PK;SSPETGTTGDVAWQIS(1)PK ; 186.75 1.60E-07 17349800 5428.2 4864.3 5230.5 5462.4 5230.9 5444 4485.7 5315 5985.7 5143.8 TRUE FALSE FALSE 4998.552242 5284.748417 5424.346931 5439.798036 5168.524934 4314.853033 4611.556669 6935.519033 5329.083685 5322.546667 0.939127932 0.992898465 1.019126232 1.022029186 0.971062399 0.810674533 0.866419208 1.303045228 1.001228175 1 12.37790098 -4.25125347 24.82704347 0.962778728 1.303045434 0.710767255 0.065958679 584.6250721 1424929.274 0.009618403 0.176827992 5.61E-05 4.25125347 0.340266706 SSPGAVAGLSNAPGT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 SSPGAVAGLSNAPGTPR 17 0 V9GYB2;U3KPY3;Q9BWG4-2;Q9BWG4 V9GYB2 SSBP4 Single-stranded DNA-binding protein 4 1 0 SSPGAVAGLSNAPGT(1)PR;SSPGAVAGLS(0.001)NAPGT(0.999)PR ; 191.41 5.36E-07 20133300 3332.2 2753.9 3482.1 3008.2 3175.3 3387.8 2096.14 6112.2 3377.5 2508.3 TRUE FALSE FALSE 3068.452854 2991.934845 3611.149689 2995.752865 3137.436621 2685.132092 2154.952047 7975.781643 3006.9967 2595.463238 1.18223707 1.152755624 1.391331473 1.15422666 1.208815665 1.034548304 0.830276467 3.072970376 1.158558771 1 11.34177634 -4.256475729 24.99940672 1.108963452 3.072971182 0.945615565 0.140205106 86.14180122 433838.4624 0.020478931 0.227300037 5.54E-05 4.256475729 1.964007731 SSPGLYTSPGQDSLQPTAVSPPYGGDIS(ph)PVSPSR ddPTM_HeLa_Curcumin_4h_R1 1 SSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSR 34 0 Q8N3V7-2;Q8N3V7-3;Q8N3V7 Q8N3V7-2 SYNPO Synaptopodin 1 0 SSPGLYTSPGQDS(0.001)LQPT(0.001)AVS(0.003)PPY(0.003)GGDIS(0.58)PVS(0.205)PS(0.205)R 55.714 0.0029406 0 879.39 606.05 639.62 724.6 791.46 635.94 465.22 969.6 875.07 586.34 TRUE FALSE FALSE 809.7853536 658.4342615 663.3248799 721.6017972 782.0223564 504.0388755 478.2728211 1265.226577 779.0770103 606.7152714 1.334704089 1.085244253 1.093305066 1.189358223 1.288944573 0.830766752 0.788298636 2.085371238 1.284089996 1 9.244875815 -4.248666401 24.60760431 1.122334086 2.085371999 0.732798878 0.178127077 737.605968 1420993.834 0.026807813 0.642478624 5.64E-05 4.248666401 0.963037914 SSPGQT(ph)PEEGAQALAEFAALHGPALR ddPTM_HeLa_Curcumin_4h_R1 1 SSPGQTPEEGAQALAEFAALHGPALR 26 0 Q14166 Q14166 TTLL12 Tubulin--tyrosine ligase-like protein 12 1 0 S(0.279)S(0.279)PGQT(0.441)PEEGAQALAEFAALHGPALR 54.261 0.0069965 2527700 633.21 610.68 543.57 438.72 452.67 590.97 583.71 471.74 724.31 770.2 TRUE FALSE FALSE 583.0907603 663.4644581 563.7151824 436.9046929 447.2722059 468.3961604 600.0873316 615.5713544 644.8550051 796.9643927 0.731639664 0.832489461 0.70732794 0.548211058 0.561219811 0.58772533 0.752966302 0.772395053 0.809139042 1 9.638371458 -8.798027361 0.425168471 1.051540856 0.650202376 0.405700505 0.101772636 0.747829676 0.233619756 0.130924148 0.033425994 1.59E-09 8.798027361 -0.401338481 SNVSS(ph)PATPTASSSSSTT(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 SNVSSPATPTASSSSSTTPTR 21 0 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 S(0.035)NVS(0.026)S(0.938)PATPT(0.212)AS(0.058)S(0.042)S(0.058)S(0.088)S(0.065)T(0.183)T(0.281)PT(0.014)R 160.2 4.31E-06 11128000 3573.8 2996.3 3120.1 3323 2984.3 3944.1 2772.1 1023.9 3481 2985 TRUE FALSE FALSE 3290.929959 3255.286821 3235.733651 3309.250306 2948.714172 3126.049201 2849.877665 1336.082397 3099.143009 3088.728528 1.065464294 1.053924549 1.047594057 1.071395649 0.954669258 1.01208286 0.922670167 0.432567118 1.00337177 1 11.59279736 -4.156324642 2.013427833 1.031864555 0.137716985 0.9636487 0.034408529 0.142594664 0.486964375 0.005328771 0.256181163 6.98E-05 4.156324642 -0.89414757 down SSPNPFVGS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 2 SSPNPFVGSPPK 12 0 P98082-3;P98082 P98082-3 DAB2 Disabled homolog 2 1 0 S(0.001)S(0.001)PNPFVGS(0.998)PPK;S(0.012)S(0.045)PNPFVGS(0.943)PPK ; 132.23 0.0021845 658760000 8252.2 8186.2 8148.1 9025.7 9694.9 10573.3 9118.3 8983.5 8894.5 7091 TRUE FALSE FALSE 7599.029662 8893.778651 8450.075754 8988.354045 9579.294649 8380.278394 9374.134957 11722.5278 7918.795603 7337.411722 1.035655344 1.212113888 1.151642578 1.225003364 1.305541383 1.142130047 1.277580612 1.597638001 1.079235554 1 12.84105553 -1 0.213332279 0.974153014 3.591285233 0.704289169 0.088231278 17.46463945 0.206296077 0.06875984 15.72405227 0.1 1 2.617132219 SSPNPFVGS(ph)PPKGLSIQNGVK ddPTM_HeLa_Curcumin_4h_R1 2 SSPNPFVGSPPKGLSIQNGVK 21 1 P98082-3;P98082 P98082-3 DAB2 Disabled homolog 2 1 0 S(0.001)S(0.001)PNPFVGS(0.956)PPKGLS(0.043)IQNGVK;SSPNPFVGS(0.995)PPKGLS(0.005)IQNGVK ; 80.786 0.00049563 507690000 3481.6 2994.85 3436.8 3036.26 2924.4 3842.6 2865.4 3675.5 3993.3 2957 TRUE FALSE FALSE 3206.027686 3253.711489 3564.170831 3023.696761 2889.52844 3045.601445 2945.795412 4796.14303 3555.244981 3059.75553 1.047805178 1.063389365 1.164854772 0.988215147 0.944365787 0.995374112 0.962755156 1.567492234 1.161937595 1 11.57920067 -4.257586815 24.99824146 1.022892587 1.567492443 0.823528381 0.073494386 92.6424778 601107.011 0.008446127 0.084862532 5.53E-05 4.257586815 0.544599856 SSPNVANQPPS(ph)PGGK ddPTM_HeLa_Curcumin_4h_R1 1 SSPNVANQPPSPGGK 15 0 A8MQ02;J3KN01;P55196-3;P55196;P55196-5;Q5TIG5;P55196-2;P55196-6;P55196-1 A8MQ02 MLLT4 Afadin 1 0 SSPNVANQPPS(1)PGGK 185.74 2.13E-05 10714000 3371.5 2677 2949.4 3143 2859.2 3975.8 4223.9 4514.9 3348.2 2848.4 TRUE FALSE FALSE 3104.642217 2908.387952 3058.707359 3129.995099 2825.105907 3151.174263 4342.411266 5891.472226 2980.910837 2947.381688 1.053356011 0.986770042 1.03777104 1.061957843 0.958513761 1.069143598 1.473311476 1.998883365 1.01137591 1 11.52521819 -4.424210402 1.888064632 1.020838834 2.136235553 0.988138342 0.033816947 0.044640501 0.209827533 0.005315587 0.07739912 3.77E-05 4.424210402 1.115396719 SSPQLDPLRKS(ph)PT(ph)MEQAVQTASAHLPAPAAVGR ddPTM_HeLa_Curcumin_4h_R1 1 SSPQLDPLRKSPTMEQAVQTASAHLPAPAAVGR 33 2 Q8ND56-3;Q8ND56-2;Q8ND56 Q8ND56-3 LSM14A Protein LSM14 homolog A 2 0 S(0.293)S(0.293)PQLDPLRKS(0.704)PT(0.704)MEQAVQT(0.007)AS(0.001)AHLPAPAAVGR 52.234 0.0017878 49585000 431.3 339.53 353.26 411.74 540.77 1004.8 408.86 141.33 575.03 382.49 TRUE FALSE FALSE 397.1621499 368.8774603 366.3521264 410.036329 534.3216709 796.3931536 420.3315112 184.4208664 511.9506477 395.781499 1.003488417 0.932023001 0.925642374 1.036016918 1.350042062 2.012204096 1.062029206 0.465966365 1.293518391 1 8.628560364 -5.855543376 5.92216959 0.99010411 1.266475334 0.049877994 0.366909436 0.355073903 18.39744395 0.05240866 0.096187063 1.39E-06 5.855543376 0.276371224 SSPS(ph)PEVVKPK ddPTM_HeLa_Curcumin_4h_R1 2 SSPSPEVVKPK 11 1 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 0 S(0.031)S(0.13)PS(0.839)PEVVKPK;S(0.106)S(0.106)PS(0.787)PEVVKPK ; 79.639 0.012384 69135000 10057.2 7747.8 8692.7 9128.8 8865 10641.6 8517.3 3513.7 10398 8699 TRUE FALSE FALSE 9261.162008 8417.485308 9014.859109 9091.027444 8759.290665 8434.412204 8756.272515 4585.010955 9257.365415 9001.289603 1.028870575 0.93514215 1.001507507 1.009969443 0.973115081 0.937022646 0.97277978 0.509372674 1.028448792 1 13.13591599 -4.252514302 4.113395834 0.999141564 0.464097522 0.950905703 0.032537361 0.037966863 1.370296359 0.004883641 0.060427056 5.59E-05 4.252514302 -0.535044042 SSPSTGS(ph)LDSGNESK ddPTM_HeLa_Curcumin_4h_R1 1 SSPSTGSLDSGNESK 15 0 A0A0U1RQT1;A0A087X1H5;Q15057 A0A0U1RQT1 ACAP2 "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2" 1 0 SSPST(0.024)GS(0.975)LDSGNESK 210.67 4.95E-10 19614000 3519.2 3346.3 3526.5 3572.7 4130.6 3674 2219.8 1422.2 3290.2 2914 TRUE FALSE FALSE 3240.651607 3635.539261 3657.195192 3557.917114 4081.345293 2911.970985 2282.081614 1855.822233 2929.273292 3015.261283 1.074749848 1.205712845 1.212894953 1.179969754 1.35356273 0.965744163 0.756843736 0.615476424 0.971482408 1 11.55806731 -4.763433419 2.874239692 1.093821285 0.65024588 0.704857314 0.115024126 0.126842429 2.07339054 0.018219506 0.079963205 1.72E-05 4.763433419 -0.443575405 SSPSVLIHS(ph)LGK ddPTM_HeLa_Curcumin_4h_R1 1 SSPSVLIHSLGK 12 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3 RAI14 Ankycorbin 1 0 SSPSVLIHS(1)LGK 112.02 0.004978 17814000 1381.3 1393.3 1158.5 959.64 1420.7 1984 1730.7 703.74 1452.4 1359.5 TRUE FALSE FALSE 1271.968647 1513.730644 1201.435029 955.669264 1403.75908 1572.496036 1779.258784 918.3070864 1293.075354 1406.742524 0.904194354 1.076053804 0.854054675 0.679349097 0.997879183 1.117827896 1.264807706 0.65278974 0.919198312 1 10.45814258 -5.529842549 24.91779478 0.934224169 1.040565946 0.056247615 0.174236128 338.5305768 1211324.721 0.024191708 0.048466254 2.95E-06 5.529842549 0.106341777 SSPVCSTAPVETEPKLS(ph)PSWNPK ddPTM_HeLa_Curcumin_4h_R1 2 SSPVCSTAPVETEPKLSPSWNPK 23 1 Q96BY7 Q96BY7 ATG2B Autophagy-related protein 2 homolog B 1 0 SSPVCSTAPVET(0.001)EPKLS(0.783)PS(0.217)WNPK;SSPVCSTAPVET(0.003)EPKLS(0.788)PS(0.209)WNPK ; 101.59 1.95E-05 43631000 2627.98 2206.19 2171.95 2788.81 2108.17 2956.2 2011.89 1712.63 3020.56 2044.43 TRUE FALSE FALSE 2419.97261 2396.883233 2252.444378 2777.270643 2083.03145 2343.050797 2068.338219 2234.803003 2689.212125 2115.47379 1.143938829 1.133024311 1.064747003 1.312836234 0.984664267 1.107577323 0.977718669 1.056407795 1.271210325 1 11.0467651 -4.771165001 24.97263303 1.087405683 1.017063227 0.056601972 0.105873508 352.613384 905421.0232 0.013130264 0.040137352 1.69E-05 4.771165001 -0.070342456 SSPVNRPSSATNK(ac)ALSPVTSR ddPTM_HeLa_Curcumin_4h_R1 1 SSPVNRPSSATNKALSPVTSR 21 2 Q96L91-4;Q96L91-3;Q96L91-5;Q96L91-2;Q96L91;A0A0A0MR72;A0A0A0MR80 Q96L91-4 EP400 E1A-binding protein p400 0 1 SSPVNRPSSATNK(1)ALSPVTSR 110.61 2.34E-05 6952800 444.51 535.16 502.41 540.04 290.13 587.51 556.53 370.94 464.95 424.27 FALSE TRUE FALSE 409.3265645 581.4168458 521.0297566 537.8054576 286.6703892 465.6538034 572.144734 484.0378984 413.9461482 439.0133509 0.932378397 1.324371672 1.186819844 1.225032124 0.652987862 1.060682557 1.303251331 1.102558493 0.942901047 1 8.778121004 SSQDGDTPAQAS(ph)PPEEK ddPTM_HeLa_Curcumin_4h_R1 1 SSQDGDTPAQASPPEEK 17 0 E9PNX6;A0A0C4DGE6;E9PNT2;E9PIR1;A0A0G2JRG8;A0A0G2JNY3;Q6ZUM4-2;Q6ZUM4-3;Q6ZUM4 E9PNX6 ARHGAP27 Rho GTPase-activating protein 27 1 0 SSQDGDT(0.001)PAQAS(0.999)PPEEK 124.45 0.00045818 7066100 4954.1 4338 4366.3 4770.4 4580.6 5321.4 3918.8 3057.4 4794 4080.8 TRUE FALSE FALSE 4561.977757 4712.95739 4528.118919 4750.661349 4525.979337 4217.681655 4028.750981 3989.587185 4268.110194 4222.607496 1.080369833 1.116124905 1.072351367 1.125053975 1.07184467 0.99883346 0.954090804 0.944816015 1.010775971 1 12.04391844 -4.992113134 2.976139403 1.055937372 0.949388053 0.601342904 0.038531765 0.179229819 3.214969552 0.006894223 0.023099915 1.02E-05 4.992113134 -0.10654932 SSQGK(ac)TEVK ddPTM_HeLa_Curcumin_4h_R1 2 SSQGKTEVK 9 1 Q96EV2;H0Y3K4 Q96EV2 RBM33 RNA-binding protein 33 0 1 ; SSQGK(1)TEVK;SSQGK(1)TEVK 156.16 4.91E-08 6277900 2121.53 2810.1 2453.7 1423.35 1753.64 2961 1716.17 1911.33 2008.72 1857.85 FALSE TRUE FALSE 1953.608662 3052.992522 2544.63628 1417.460555 1732.728988 2346.855223 1764.321111 2494.085718 1788.368442 1922.410149 1.016228853 1.588106744 1.323669812 0.737335139 0.901331586 1.22078799 0.917765188 1.297374402 0.930274137 1 10.90870045 -7.478827561 24.99943399 1.007159291 1.130869148 0.085256887 0.23258979 1066.317513 605148.4016 0.040772364 0.046336619 3.32E-08 7.478827561 0.123709857 SDADSGFLGLRPT(ph)SVDPALR ddPTM_HeLa_Curcumin_4h_R1 1 SDADSGFLGLRPTSVDPALR 20 1 Q9NZM5 Q9NZM5 GLTSCR2 Glioma tumor suppressor candidate region gene 2 protein 1 0 SDADSGFLGLRPT(0.5)S(0.5)VDPALR 70.944 0.0050037 4915200 3336.7 2956.9 2940.3 2566.6 2520.1 2971.7 1925.2 958.08 3430.3 2742.6 TRUE FALSE FALSE 3072.596674 3212.48126 3049.270105 2555.980089 2490.049453 2355.335922 1979.215931 1250.194182 3054.004672 2837.905146 1.082698863 1.131990357 1.074479219 0.900657336 0.877425187 0.82995583 0.697421453 0.440534168 1.076147551 1 11.47061065 -4.154693451 0.627430356 1.048900726 4.70E-15 0.929977567 0.053906267 0.752747323 0.184705906 0.011238967 0.583566527 7.00E-05 4.154693451 -1.048900726 down GSLSLS(ph)FEREPSTSDLGTTDVQK ddPTM_HeLa_Curcumin_4h_R1 2 GSLSLSFEREPSTSDLGTTDVQK 23 1 P57078-2;P57078 P57078-2 RIPK4 Receptor-interacting serine/threonine-protein kinase 4 1 0 GS(0.026)LS(0.07)LS(0.898)FEREPS(0.002)T(0.002)S(0.002)DLGTTDVQK;GS(0.014)LS(0.044)LS(0.925)FEREPS(0.005)T(0.005)S(0.005)DLGT(0.001)TDVQK ; 72.499 0.00060904 17506200 2416.8 2112.62 1817.22 2327.3 2044.33 2294.4 1549.1 674.34 2411.51 2218.11 TRUE FALSE FALSE 2225.50773 2295.225459 1884.567772 2317.670249 2019.9527 1818.515577 1592.563577 879.9431617 2146.973386 2295.189157 0.969640224 1.000015816 0.821094752 1.009794875 0.880081144 0.792316211 0.693870295 0.3833859 0.935423287 1 11.16439734 -4.154243798 0.768609722 0.978787062 7.02E-19 0.903890766 0.057105249 0.544421777 0.204956947 0.008536846 0.473910519 7.01E-05 4.154243798 -0.978787062 down SSQLGMEEEDVIEVY(ph)QEQTGGHS(ph)T(ph)V ddPTM_HeLa_Curcumin_4h_R1 1 SSQLGMEEEDVIEVYQEQTGGHSTV 25 0 B8ZZN6 B8ZZN6 SUMO1 3 0 SSQLGMEEEDVIEVY(0.595)QEQT(0.595)GGHS(0.905)T(0.905)V 48.641 0.0072598 0 1781.7 1211.4 1409.2 1872.9 1742.7 1797.1 1708.5 1118.8 1831.5 1811.6 TRUE FALSE FALSE 1640.676565 1316.108018 1461.426192 1865.150436 1721.919441 1424.361203 1756.435912 1459.91697 1630.589032 1874.552965 0.875236174 0.702091668 0.779613176 0.994984122 0.918576041 0.759840468 0.936989215 0.778808066 0.869854873 1 10.87233087 -8.630103965 0.945618397 0.988149857 0.846728763 0.078333959 0.093820478 0.467786364 0.845767196 0.035323904 0.017846933 2.34E-09 8.630103965 -0.141421094 SSQPLASK(ac)QEK ddPTM_HeLa_Curcumin_4h_R1 2 SSQPLASKQEK 11 1 P17096;P17096-2;P17096-3;A0A669KAX1 P17096 HMGA1 High mobility group protein HMG-I/HMG-Y 0 1 ; SSQPLASK(1)QEK;SSQPLASK(1)QEK 209.19 9.90E-23 623620000 21046 15756.1 17386 18475.7 19664.1 23622 22563 19948.6 20243.2 16164.3 FALSE TRUE FALSE 19380.18689 17117.98708 18030.34045 18399.25245 19429.61845 18722.53093 23196.05705 26030.83631 18022.57161 16726.00822 1.158685721 1.02343529 1.077982279 1.100038467 1.161641092 1.119366359 1.38682564 1.556308951 1.077517801 1 14.02980556 -4.437660577 1.198877264 1.075698593 1.710251113 0.910420905 0.049285135 0.295312498 0.434266985 0.009656695 0.21390643 3.65E-05 4.437660577 0.63455252 SSQPS(ph)PTAVPASDS(ph)PPTK ddPTM_HeLa_Curcumin_4h_R1 1 SSQPSPTAVPASDSPPTK 18 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 0 S(0.026)S(0.032)QPS(0.878)PT(0.085)AVPAS(0.103)DS(0.599)PPT(0.278)K 107.83 0.0020913 31273000 2752.2 2488.1 2631.8 2360.9 2507.2 2401.6 2124.6 5465.2 2036 1793.2 TRUE FALSE FALSE 2534.360466 2703.160277 2729.336823 2351.131221 2477.303278 1903.481088 2184.210558 7131.514321 1812.655894 1855.513567 1.365853913 1.45682593 1.47093337 1.267105379 1.335103834 1.025851345 1.1771461 3.843418043 0.976902528 1 10.85760283 -4.260837707 24.89161091 1.222334778 3.843418898 0.953081809 0.173903404 7.606513628 314606.548 0.027170622 0.216594807 5.48E-05 4.260837707 2.62108412 SSQPSPT(ph)AVPAS(ph)DSPPTK ddPTM_HeLa_Curcumin_4h_R1 1 SSQPSPTAVPASDSPPTK 18 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 0 S(0.001)S(0.001)QPS(0.354)PT(0.645)AVPAS(0.544)DS(0.448)PPT(0.008)K 120.79 0.0015693 32601000 3052.4 2952.9 3177.5 3169.7 3422.9 3059.4 2705.4 4090.1 2709.1 2594.1 TRUE FALSE FALSE 2810.799319 3208.135518 3295.260945 3156.584621 3382.084153 2424.845953 2781.306243 5337.152661 2411.918508 2684.244782 1.047147167 1.195172489 1.227630568 1.175967498 1.259976056 0.903362454 1.036159691 1.988325617 0.898546408 1 11.39030052 -4.260284513 24.98245156 1.066759398 1.988325915 0.828441054 0.123450608 28.14170771 608693.2199 0.016960575 0.140013602 5.49E-05 4.260284513 0.921566516 SSQPSPT(ph)AVPASDSPPTK ddPTM_HeLa_Curcumin_4h_R1 1 SSQPSPTAVPASDSPPTK 18 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 SSQPS(0.181)PT(0.819)AVPASDSPPTK 159.4 0.0001091 14114000 6580.4 4864.3 6193.9 5728.8 5730.4 5345 5246.6 4060 5981.8 6154.4 TRUE FALSE FALSE 6059.554396 5284.748417 6423.451383 5705.095744 5662.068723 4236.386749 5393.805475 5297.87531 5325.611506 6368.264942 0.951523602 0.829856871 1.008665852 0.895863441 0.889106966 0.665234061 0.846981953 0.831918169 0.836273546 1 12.63668464 -6.075664692 0.465142237 0.988710883 0.767650609 0.181191713 0.085920377 0.798157995 0.304547495 0.021274146 0.075880583 8.40E-07 6.075664692 -0.221060274 SSQPSPT(ph)AVPASDSPPTKQEVK ddPTM_HeLa_Curcumin_4h_R1 4 SSQPSPTAVPASDSPPTKQEVK 22 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 S(0.008)S(0.008)QPS(0.173)PT(0.736)AVPAS(0.071)DS(0.005)PPTKQEVK;S(0.014)S(0.014)QPS(0.233)PT(0.735)AVPAS(0.005)DSPPTKQEVK;S(0.001)S(0.001)QPS(0.067)PT(0.875)AVPAS(0.009)DS(0.046)PPTKQEVK;S(0.009)S(0.009)QPS(0.468)PT(0.509)AVPAS(0.005)DSPPTKQEVK ;;; 102.67 0.00013595 35649000 16317.7 11409.7 12369.8 13643.8 10761.9 12611.7 10492.4 10066.9 20216.2 15266.3 TRUE FALSE FALSE 15026.13683 12395.90363 12828.23567 13587.34557 10633.57137 9995.891257 10786.78851 13136.25147 17998.53344 15796.80279 0.951213801 0.784709653 0.812077978 0.860132633 0.673147061 0.632779392 0.682846311 0.831576595 1.139378245 1 13.94734497 -6.926993764 0.713796289 0.992554239 0.70571699 0.7100876 0.081173997 0.224329516 0.234429137 0.01641362 0.024554549 1.18E-07 6.926993764 -0.286837249 SSQPSPTAVPASDS(ph)PPTK ddPTM_HeLa_Curcumin_4h_R1 1 SSQPSPTAVPASDSPPTK 18 0 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 SSQPS(0.013)PT(0.1)AVPAS(0.018)DS(0.867)PPT(0.002)K 195.72 3.60E-09 34713000 6511.9 4760.5 5808.6 5711.5 5115.8 5180.4 4160.5 3965.8 6142.7 5498.9 TRUE FALSE FALSE 5996.476244 5171.976408 6023.871826 5687.867326 5054.797426 4105.926645 4277.232433 5174.954164 5468.861178 5689.986366 1.053864782 0.908961125 1.058679483 0.999627584 0.88836723 0.721605709 0.751712246 0.909484458 0.961137835 1 12.47420948 -5.612347426 3.061360385 1.017929174 0.790558625 0.670496386 0.062937017 0.091753967 1.724538161 0.008691971 0.018889185 2.44E-06 5.612347426 -0.227370549 SSQQPS(ph)TPQQAPPGQPQQGTFVAHK ddPTM_HeLa_Curcumin_4h_R1 1 SSQQPSTPQQAPPGQPQQGTFVAHK 25 0 E7ERS3;Q86VM9;H3BRH3 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 0 S(0.011)S(0.011)QQPS(0.58)T(0.398)PQQAPPGQPQQGTFVAHK 115.06 8.53E-09 14090000 2718.8 2140.8 2103.9 2435.2 2604.5 3401.2 2916.1 1676.3 3089.2 2308.2 TRUE FALSE FALSE 2503.604111 2325.841213 2181.872385 2425.123788 2573.443039 2695.752781 2997.917918 2187.396153 2750.322489 2388.409778 1.048230557 0.973803254 0.913525143 1.015371738 1.077471321 1.128681018 1.255194123 0.915837882 1.151528734 1 11.22183466 -5.634601927 3.412092652 1.009594315 1.114032875 0.129989789 0.09578221 0.255985055 5.833425288 0.011851534 0.025060568 2.32E-06 5.634601927 0.10443856 SSQQPST(ph)PQQAPPGQPQQGTFVAHK ddPTM_HeLa_Curcumin_4h_R1 1 SSQQPSTPQQAPPGQPQQGTFVAHK 25 0 E7ERS3;Q86VM9;H3BRH3 E7ERS3 ZC3H18 Zinc finger CCCH domain-containing protein 18 1 0 S(0.021)S(0.021)QQPS(0.248)T(0.711)PQQAPPGQPQQGTFVAHK 79.304 0.00015856 15074000 2353.9 1998.8 2308.7 2302.6 2329.1 3374.8 3242.3 1775.3 2484.3 2104 TRUE FALSE FALSE 2167.586331 2171.567366 2394.262453 2293.072451 2301.327004 2674.828438 3333.270212 2316.580798 2211.778505 2177.113843 0.995623788 0.997452371 1.099741504 1.053262538 1.057054049 1.228612112 1.531050028 1.064060478 1.015922301 1 11.08820113 -5.233915527 3.109070887 1.011476685 1.312598659 0.50489851 0.110352261 0.122598595 2.400895198 0.014180714 0.038688003 5.84E-06 5.233915527 0.301121974 SSQQQTQPQK(ac)QR ddPTM_HeLa_Curcumin_4h_R1 2 SSQQQTQPQKQR 12 1 F5H7M9;F5H3E1;F5H2E6;A0A0C4DGG8;Q8IX12-2;Q8IX12 F5H7M9 CCAR1 Cell division cycle and apoptosis regulator protein 1 0 1 ; SSQQQTQPQK(1)QR;SSQQQTQPQK(1)QR 175.74 2.38E-07 291960 0 0 75.44 78.524 79.927 144.98 0 0 0 0 FALSE TRUE FALSE 0 0 78.23587276 78.19908849 78.97392273 114.9095137 0 0 0 0 0 SVELDLNQAHMEET(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SVELDLNQAHMEETPK 16 0 Q14680-3;Q14680-4;Q14680-5;Q14680-2;Q14680-8;Q14680-6;Q14680;Q14680-7 Q14680-3 MELK Maternal embryonic leucine zipper kinase 1 0 S(0.294)VELDLNQAHMEET(0.706)PK 140.17 0.010492 11909000 3809.3 3176.5 3343.7 3404.6 3072.2 3447.3 2372.1 1088.2 3291.8 3418.4 TRUE FALSE FALSE 3507.789885 3451.062506 3467.620463 3390.512667 3035.566022 2732.291121 2438.654742 1419.987171 2930.697776 3537.189146 0.991688525 0.975651107 0.980332213 0.958533041 0.858185948 0.772446993 0.689432948 0.401445077 0.828538609 1 11.78838765 -4.153979371 0.667289152 0.996530991 3.81E-18 0.893871783 0.058318304 0.264832215 0.073834393 0.003873591 0.206433474 7.01E-05 4.153979371 -0.996530991 down SSQSEGIFLGS(ph)ESDEDSVR ddPTM_HeLa_Curcumin_4h_R1 1 SSQSEGIFLGSESDEDSVR 19 0 Q9BYW2;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 0 SSQSEGIFLGS(0.62)ES(0.38)DEDSVR 209.23 8.87E-14 20373000 2316.7 2162.8 2276.1 2485.8 2503.9 2445.1 2020 1395.8 2417.6 2210.9 TRUE FALSE FALSE 2133.33075 2349.742795 2360.454268 2475.514418 2474.042628 1937.958698 2076.675763 1821.372995 2152.395329 2287.72861 0.932510413 1.027107317 1.03178946 1.082083953 1.081440612 0.8471104 0.90774568 0.796149065 0.940843822 1 11.1597002 -5.237729912 24.82251359 0.992181389 0.856076082 0.626350375 0.056068694 471.2441975 493366.0096 0.00893915 0.022774542 5.78E-06 5.237729912 -0.136105306 SSQSEGIFLGSES(ph)DEDSVR ddPTM_HeLa_Curcumin_4h_R1 1 SSQSEGIFLGSESDEDSVR 19 0 Q9BYW2;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 0 SSQSEGIFLGS(0.202)ES(0.755)DEDS(0.043)VR 69.922 0.010352 18167000 679.32 363.87 604.75 418.35 479.74 544.82 495.76 371.65 688.37 528.39 TRUE FALSE FALSE 625.5511052 395.3213014 627.162567 416.6189785 474.0194138 431.8181906 509.6696913 484.9643741 612.8575332 546.7515132 1.144123226 0.723036502 1.147070565 0.761989621 0.866974123 0.789788744 0.932177926 0.886992285 1.120906881 1 9.094741498 -7.27671984 24.99661837 1.068058191 0.877772697 0.418289141 0.115751409 610.9136237 999363.8632 0.01919718 0.021995463 5.29E-08 7.27671984 -0.190285493 SSRGQEEIS(ph)GALPVAS(ph)PASSR ddPTM_HeLa_Curcumin_4h_R1 1 SSRGQEEISGALPVASPASSR 21 1 Q9UBK8;Q9UBK8-1;H0Y9D5;H0Y8S9 Q9UBK8 MTRR Methionine synthase reductase 2 0 S(0.272)S(0.347)RGQEEIS(0.381)GALPVAS(0.503)PAS(0.424)S(0.073)R 105.95 0.00025163 14550000 2673.2 1948.8 2473.1 3020.8 2516.8 4418.8 3551.6 1415.3 3036.9 2346.4 TRUE FALSE FALSE 2461.613399 2117.245588 2564.755262 3008.30073 2486.788804 3502.29107 3651.248337 1846.818455 2703.759668 2427.937225 1.013870282 0.872034732 1.056351554 1.23903563 1.024239333 1.442496549 1.503847916 0.760653297 1.113603614 1 11.24551541 -6.372715435 4.102406836 0.99544716 1.215709167 0.168621748 0.20225353 0.264872433 7.70521009 0.029013275 0.045089025 4.24E-07 6.372715435 0.220262007 SSRRQAT(ph)VNVS(ph)Y(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SSRRQATVNVSYK 13 2 O14646-2;O14646 O14646-2 CHD1 Chromodomain-helicase-DNA-binding protein 1 3 0 S(0.041)S(0.234)RRQAT(0.725)VNVS(1)Y(1)K 82.651 0.0093463 10842000 675.94 817.58 1784.1 1285.4 4309 3806.3 1638.9 1322.6 2054.4 1206.4 TRUE FALSE FALSE 622.4386358 888.2479721 1850.220315 1280.081355 4257.617989 3016.830474 1684.883123 1725.854651 1829.03746 1248.32231 0.498620133 0.71155339 1.482165544 1.025441382 3.410672031 2.416707968 1.349718025 1.382539299 1.465196484 1 10.28577476 -6.236157074 2.006831434 0.769809206 2.069760676 0.340528707 0.660830395 0.224308054 1.762274431 0.102235571 0.180605087 5.81E-07 6.236157074 1.299951469 GIGLDESELDS(ph)EAELMR ddPTM_HeLa_Curcumin_4h_R1 5 GIGLDESELDSEAELMR 17 0 Q96RS0 Q96RS0 TGS1 Trimethylguanosine synthase 1 0 GIGLDESELDS(1)EAELMR;GIGLDESELDS(1)EAELMR;GIGLDESELDS(1)EAELMR;GIGLDESELDS(1)EAELMR;GIGLDESELDS(1)EAELMR ;;;; 320.06 1.67E-112 91124100 9976.8 8728.61 8523.94 9705.69 9060.75 11325.41 8067.83 2446 10835.85 9680.13 TRUE FALSE FALSE 9187.125753 9483.072154 8839.844715 9665.530426 8952.706474 8976.392302 8294.191596 3191.77414 9647.184365 10016.5138 0.917197933 0.946743782 0.882527084 0.964959528 0.893794653 0.896159331 0.828051732 0.3186512 0.963127947 1 13.29009285 -4.152772678 1.875390619 0.947087004 3.42E-15 0.961619648 0.036602585 0.178488932 0.508128919 0.006375614 0.322365127 7.03E-05 4.152772678 -0.947087004 down RNS(ph)SSPVSPASVPGQR ddPTM_HeLa_Curcumin_4h_R1 2 RNSSSPVSPASVPGQR 16 1 Q9H1B7 Q9H1B7 IRF2BPL Interferon regulatory factor 2-binding protein-like 1 0 RNS(0.577)S(0.421)S(0.002)PVSPASVPGQR;RNS(0.773)S(0.225)S(0.002)PVSPASVPGQR ; 230.96 1.02E-21 14766200 2125.1 1643.48 1684.95 1758.28 1628.77 2155.6 1247.38 530.66 2855.7 2012.34 TRUE FALSE FALSE 1956.896093 1785.535088 1747.395729 1751.004703 1609.347982 1708.504261 1282.378126 692.4557911 2542.436855 2082.268665 0.939790396 0.857495057 0.839178805 0.840911998 0.772882005 0.820501355 0.615856228 0.332548726 1.220993668 1 11.02394051 -4.150515731 0.478011453 0.968040213 6.21E-31 0.787573397 0.102138403 1.155020513 0.16408328 0.014602819 0.642652645 7.07E-05 4.150515731 -0.968040213 down PGLVTVTSSQST(ph)PAKAPR ddPTM_HeLa_Curcumin_4h_R1 2 PGLVTVTSSQSTPAKAPR 18 1 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 0 PGLVTVT(0.002)S(0.006)S(0.003)QS(0.165)T(0.824)PAKAPR;PGLVTVTS(0.002)SQST(0.998)PAKAPR ; 161.31 2.46E-05 59047000 3542.2 3432.1 2856.03 3900 3180.6 4057.6 2569.56 1063.24 3325.2 3855.3 TRUE FALSE FALSE 3261.831132 3728.755431 2961.876984 3883.862833 3142.673422 3216.008021 2641.654938 1387.416981 2960.433879 3989.271388 0.817650848 0.934695855 0.742460639 0.973576991 0.787781306 0.806164261 0.662189829 0.347787063 0.742098893 1 11.96190956 -4.150437865 0.960421836 0.902332866 1.26E-15 0.737193761 0.091054668 0.798352578 0.486132737 0.013505568 0.782958541 7.07E-05 4.150437865 -0.902332866 down SSS(ph)APNVHINTIEPVNIDDLIR ddPTM_HeLa_Curcumin_4h_R1 2 SSSAPNVHINTIEPVNIDDLIR 22 0 H7C560;A0A2U3TZI2;A0A2R8Y8E0;P15056;A0A2R8Y492;A0A2R8YDP5;A0A2R8Y679 H7C560 BRAF Serine/threonine-protein kinase B-raf 1 0 S(0.155)S(0.155)S(0.69)APNVHINTIEPVNIDDLIR;S(0.071)S(0.071)S(0.85)APNVHINT(0.008)IEPVNIDDLIR ; 157.49 5.14E-07 130582000 5138.7 4803 4873.7 4477.8 5581.7 7111.3 4175.4 4099.34 5270.5 5043.3 TRUE FALSE FALSE 4731.966473 5218.149918 5054.323609 4459.27205 5515.141873 5636.336219 4292.550486 5349.209895 4692.339336 5218.5543 0.906758117 0.999922511 0.968529466 0.854503334 1.056833283 1.080057023 0.82255549 1.025036742 0.899164609 1 12.34943448 -5.715184653 24.99995799 0.953311128 0.989718351 0.096167824 0.078295885 353.2253981 190910.7963 0.011232226 0.022464372 1.93E-06 5.715184653 0.036407222 SSS(ph)ASSPEMK ddPTM_HeLa_Curcumin_4h_R1 5 SSSASSPEMK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 SS(0.004)S(0.969)AS(0.014)S(0.014)PEMK;SS(0.001)S(0.991)AS(0.007)S(0.001)PEMK;S(0.001)S(0.022)S(0.976)AS(0.001)SPEMK;SS(0.003)S(0.955)AS(0.041)S(0.001)PEMK;SS(0.002)S(0.378)AS(0.31)S(0.31)PEMK ;;;; 119.27 0.0054716 223635300 61743.9 58896.4 56127.2 54732.8 60349.8 72901.9 67180 47505 60214.2 57779.8 TRUE FALSE FALSE 56856.80516 63987.14238 58207.32341 54506.33018 59630.16805 57781.22417 69064.88999 61989.05581 53608.85291 59787.64375 0.950979192 1.070240243 0.973567777 0.911665467 0.997366083 0.966440899 1.155169959 1.036820519 0.896654385 1 15.86755973 -4.77610007 24.96169957 0.979076892 1.095995242 0.463236573 0.053295034 116.1120058 197696.5087 0.006258786 0.018890164 1.67E-05 4.77610007 0.11691835 SSS(ph)DSWEPTSAGSK ddPTM_HeLa_Curcumin_4h_R1 1 SSSDSWEPTSAGSK 14 0 A0A3B3IRS8;B1AL16;Q8IX21;Q8IX21-2 A0A3B3IRS8 FAM178A Protein FAM178A 1 0 SS(0.009)S(0.991)DSWEPTSAGSK 172.1 0.00019799 3915200 2239.1 1683.6 1933.5 1815.9 2120.7 2461.5 2170.1 1334.1 2267.2 1728.6 TRUE FALSE FALSE 2061.872872 1829.122882 2005.157211 1808.386287 2095.412038 1950.957153 2230.987165 1740.860949 2018.493832 1788.668721 1.152741616 1.022616911 1.121033306 1.011023598 1.171492525 1.090731408 1.247289193 0.973271869 1.128489478 1 10.8046705 -9.500473113 1.185069485 0.998636394 1.106824505 0 0.087126627 0.587373128 1.445858627 0.053028012 0.012199713 3.16E-10 9.500473113 0.108188111 SSS(ph)EDAESLAPR ddPTM_HeLa_Curcumin_4h_R1 1 SSSEDAESLAPR 12 0 Q4G0J3-3;Q4G0J3;H0YA82 Q4G0J3-3 LARP7 La-related protein 7 1 0 S(0.339)S(0.056)S(0.606)EDAESLAPR 171.62 0.00013367 121540000 615.93 798.38 688.43 629.94 761.66 1195 1093.4 1029.7 671.12 788.14 TRUE FALSE FALSE 567.1784906 867.3884097 713.9438214 627.3334752 752.577702 947.1435296 1124.077861 1343.65079 597.4998151 815.5278063 0.695474129 1.063591459 0.875437742 0.769236156 0.922810597 1.161387168 1.378344003 1.647584275 0.73265413 1 9.671590258 -4.731919945 1.29952876 0.864147162 1.70239427 0.854554348 0.109571551 0.214550853 0.523752809 0.01954921 0.189774679 1.85E-05 4.731919945 0.838247109 LKSVEDEMDS(ph)PGEEPFYTGQGR ddPTM_HeLa_Curcumin_4h_R1 2 LKSVEDEMDSPGEEPFYTGQGR 22 1 A0A590UJA3;S4R3W2;A0A590UJU2;A0A590UK38;A0A590UK73;B1AKN7;B1AKN5;A0A590UK09;B1AKN8;Q12857-2;Q12857-3;Q12857;Q12857-4 A0A590UJA3 NFIA Nuclear factor 1;Nuclear factor 1 A-type 1 0 LKS(0.01)VEDEMDS(0.99)PGEEPFYTGQGR;LKS(0.001)VEDEMDS(0.999)PGEEPFYTGQGR ; 97.689 0.00038083 169603000 5574 3742.9 4399.3 5120.1 3841.6 5603.1 3144 1478.98 6626.2 4919.9 TRUE FALSE FALSE 5132.812018 4066.419598 4562.341928 5098.914383 3795.791429 4440.9539 3232.212178 1929.914194 5899.322438 5090.866159 1.008239435 0.798767729 0.896181865 1.001580914 0.745608176 0.872337587 0.634904175 0.379093485 1.158805251 1 12.31369542 -4.149758559 0.596664745 0.988185414 4.83E-32 0.776378537 0.100319736 1.131846848 0.249464234 0.015430007 0.790308556 7.08E-05 4.149758559 -0.988185414 down SSS(ph)ENDVELLTK ddPTM_HeLa_Curcumin_4h_R1 1 SSSENDVELLTK 12 0 Q9C0D6 Q9C0D6 FHDC1 FH2 domain-containing protein 1 1 0 S(0.002)S(0.051)S(0.947)ENDVELLTK 115.83 0.0039923 4674800 1280.7 706.54 915.2 1165.5 1307.9 1392 898.39 683.81 1036.6 860 TRUE FALSE FALSE 1179.331244 767.6101693 949.1181171 1160.67747 1292.304147 1103.283509 923.5964055 892.3005211 922.8875734 889.884936 1.325262622 0.862594857 1.066562742 1.304300616 1.452214881 1.239804681 1.037882953 1.002714492 1.03708641 1 9.797474994 -6.275305089 24.10670303 1.125108977 1.213369752 0.106652252 0.166429723 1391.76817 2419705.082 0.030168779 0.046230056 5.31E-07 6.275305089 0.088260775 EYPSPPPS(ph)PLR ddPTM_HeLa_Curcumin_4h_R1 1 EYPSPPPSPLR 11 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 0 EYPS(0.205)PPPS(0.795)PLR 104.07 0.0089007 6612400 3405.4 2679.5 3254.6 3148.1 3965.7 3440.6 2666.2 1013.8 3417.2 2782.6 TRUE FALSE FALSE 3135.858997 2911.10404 3375.218339 3135.073996 3918.411618 2726.980776 2741.006396 1322.902953 3042.341709 2879.295143 1.08910648 1.01104746 1.172237708 1.088833843 1.360892657 0.94710012 0.951971319 0.459453751 1.05662725 1 11.49149996 -4.146637232 1.827243136 1.071634218 0.12892773 0.75418521 0.107997375 0.468612466 1.235832519 0.01567973 0.829593166 7.13E-05 4.146637232 -0.942706488 down ESCSS(ph)PSTVGSSLTTR ddPTM_HeLa_Curcumin_4h_R1 1 ESCSSPSTVGSSLTTR 16 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;H0YEP9 E9PMC9 C11orf30;EMSY Protein EMSY 1 0 ESCS(0.026)S(0.883)PS(0.032)T(0.032)VGS(0.026)S(0.001)LTTR 193.98 2.71E-07 33488000 5320.6 4235.3 4978.3 4959.8 4709.9 5639.6 3928.1 1370.2 5222 4779.7 TRUE FALSE FALSE 4899.468896 4601.38046 5162.800177 4939.277662 4653.737519 4469.883389 4038.311914 1787.967672 4649.159665 4945.794219 0.99063339 0.930362295 1.043876868 0.998682404 0.940948473 0.90377464 0.816514342 0.361512751 0.940022868 1 12.2719865 -4.144827229 1.417389428 0.990172904 1.77E-21 0.95889341 0.037890675 0.185532833 0.26859765 0.004878685 0.280380061 7.16E-05 4.144827229 -0.990172904 down SSS(ph)ETILSSLAGSDIVK ddPTM_HeLa_Curcumin_4h_R1 4 SSSETILSSLAGSDIVK 17 0 Q01850 Q01850 CDR2 Cerebellar degeneration-related protein 2 1 0 SS(0.019)S(0.98)ETILSSLAGSDIVK;S(0.064)S(0.064)S(0.534)ET(0.337)ILSSLAGSDIVK;S(0.152)S(0.152)S(0.347)ET(0.347)ILS(0.001)S(0.001)LAGSDIVK;S(0.005)S(0.223)S(0.765)ET(0.007)ILSSLAGSDIVK ;;; 289.59 8.22E-80 103070200 7508 7193.6 8080.7 7930.4 7264.7 12233.3 9753.2 10314.9 9432.5 7821.4 TRUE FALSE FALSE 6913.733878 7815.38273 8380.177851 7897.586106 7178.073197 9695.975682 10026.84854 13459.86553 8397.778349 8093.193068 0.854265284 0.965673581 1.035460019 0.975830681 0.886927216 1.198040823 1.238923681 1.663109407 1.037634748 1 12.9824933 -3.612209447 0.772604858 0.936439439 3.092823501 0.889425224 0.074446781 1.314204729 0.277691518 0.012359477 3.101013216 0.000244225 3.612209447 2.156384062 SSS(ph)FGSVSTSSNSSK ddPTM_HeLa_Curcumin_4h_R1 3 SSSFGSVSTSSNSSK 15 0 E5RG30;E5RJ65;E5RHF1;E5RGS8;E5RH07;E5RGQ6;A0A0C4DGW2;P57768-2;P57768 E5RG30 SNX16 Sorting nexin-16 1 0 S(0.04)S(0.04)S(0.915)FGS(0.005)VSTSSNSSK;SS(0.002)S(0.957)FGS(0.041)VSTSSNSSK;S(0.03)S(0.043)S(0.907)FGS(0.019)VSTSSNSSK ;; 282.73 7.10E-64 18127300 7997.6 6589.5 6611.9 7099.4 8075.8 9635.1 7073.2 2409.21 8884.7 6962.4 TRUE FALSE FALSE 7364.581521 7159.067018 6856.94283 7070.024564 7979.501359 7636.67165 7271.654955 3143.767038 7910.070638 7204.342882 1.022241951 0.993715476 0.951779079 0.981355924 1.107596 1.060009466 1.009343263 0.436371101 1.097958657 1 12.81465113 -4.261521108 8.351808266 1.013564548 0.432595477 0.929296908 0.048610445 0.014060666 14.17901772 0.005830333 0.045889976 5.48E-05 4.261521108 -0.580969071 SSS(ph)KDSRPSQAAGDNQGDEAKEQTFSGGTSQDTK ddPTM_HeLa_Curcumin_4h_R1 1 SSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTK 34 3 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 S(0.207)S(0.207)S(0.47)KDS(0.094)RPS(0.012)QAAGDNQGDEAKEQT(0.004)FS(0.004)GGT(0.001)S(0.001)QDTK 41.303 0.0082267 37617000 3163.3 2345.4 2441.9 2788.8 2614.7 3918.8 2474.9 1664 3633.8 3008.3 TRUE FALSE FALSE 2912.921467 2548.125925 2532.398962 2777.260685 2583.52141 3105.996706 2544.339033 2171.34594 3235.181231 3112.838201 0.935776702 0.818586049 0.813533759 0.892195644 0.829956857 0.997802168 0.817369509 0.697545391 1.039302727 1 11.60401488 -1.146926922 0.042255587 1.407940473 1.78E-06 0.506808874 0.071839582 395.9490752 1.316954391 11.92462845 39.60713361 0.071297299 1.146926922 -1.407938689 SSS(ph)LDALGPTR ddPTM_HeLa_Curcumin_4h_R1 2 SSSLDALGPTR 11 0 E5RI90;Q9H425-2;Q9H425-3;Q9H425 E5RI90 C1orf198 Uncharacterized protein C1orf198 1 0 S(0.003)S(0.006)S(0.991)LDALGPTR;S(0.003)S(0.011)S(0.986)LDALGPTR ; 162.49 0.00030547 25307000 4254.3 4081 4229.7 4911.5 4597.8 6227 6230.5 4664.1 4575 3841.6 TRUE FALSE FALSE 3917.567666 4433.743455 4386.456403 4891.177514 4542.974238 4935.450007 6405.311061 6086.162619 4073.133946 3975.095314 0.985527983 1.115380414 1.103484585 1.230455405 1.142859197 1.241592872 1.611360371 1.53107338 1.024663215 1 11.95677374 -4.244441162 0.433376764 0.987232539 2.089422902 0.860760932 0.076285439 1.106697397 0.138224006 0.018055673 0.628983647 5.70E-05 4.244441162 1.102190362 SSS(ph)LDMNR ddPTM_HeLa_Curcumin_4h_R1 3 SSSLDMNR 8 0 E9PMG1;H0YDT0;Q96D71-4;Q96D71-3;Q96D71 E9PMG1 REPS1 RalBP1-associated Eps domain-containing protein 1 1 0 SSS(1)LDMNR;SS(0.004)S(0.996)LDMNR;SSS(1)LDMNR ;; 164.97 0.00036094 658587000 18652.2 15479.9 16650.1 17744.3 16566.4 18728.7 14345.6 12399.4 18537.4 17605.8 TRUE FALSE FALSE 17175.85869 16817.91358 17267.16735 17670.87879 16368.8565 14844.1565 14748.09893 16179.91998 16503.8936 18217.60024 0.942816752 0.923168439 0.947828865 0.969989381 0.898518811 0.814825021 0.809552232 0.888147713 0.905931263 1 14.15304531 -5.144138628 0.295069214 0.993097931 0.755652428 0.431771865 0.044053651 2.18689669 0.214065105 0.021378065 0.178541397 7.18E-06 5.144138628 -0.237445503 SSS(ph)LESLQTAVAEVR ddPTM_HeLa_Curcumin_4h_R1 2 SSSLESLQTAVAEVR 15 0 R4GN62;A0A087WZG6;A0A087X1S9;Q8TEW8-5;Q8TEW8-2;Q8TEW8 R4GN62 PARD3B Partitioning defective 3 homolog B 1 0 SS(0.006)S(0.994)LESLQTAVAEVR;S(0.005)S(0.064)S(0.931)LESLQTAVAEVR ; 293.52 1.17E-77 10921400 3495.2 2993.9 3620.9 3853.7 3775.8 3891.7 3238.6 2302.01 4060.6 3545.4 TRUE FALSE FALSE 3218.551232 3252.679375 3755.093739 3837.75441 3730.776051 3084.517552 3329.4664 3003.882252 3615.162339 3668.602386 0.87732354 0.886626304 1.023576104 1.046108029 1.016947507 0.840788188 0.90755717 0.818808346 0.985433132 1 11.84101483 -5.244873092 24.90536142 0.955152077 0.860901821 0.440277889 0.0589983 833.0257646 1252348.76 0.010098329 0.025665557 5.69E-06 5.244873092 -0.094250257 SSS(ph)LGSTPHEELER ddPTM_HeLa_Curcumin_4h_R1 2 SSSLGSTPHEELER 14 0 B1AKL4;Q9NRA8;Q9NRA8-3;Q9NRA8-2 B1AKL4 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 0 S(0.029)S(0.113)S(0.858)LGSTPHEELER;S(0.032)S(0.224)S(0.742)LGS(0.001)TPHEELER ; 110.55 0.0028884 13442800 4428 4182.6 4204.2 4262.9 3965.1 5483.4 3281.6 2437.3 5268.7 4121.7 TRUE FALSE FALSE 4077.519128 4544.125307 4360.01135 4245.261249 3917.818772 4346.081029 3373.672864 3180.42155 4690.736792 4264.928768 0.956057967 1.065463353 1.022294061 0.995388547 0.918612944 1.019027812 0.791026778 0.745715045 1.099839422 1 12.05830593 -4.702989222 5.374584415 0.987042507 0.759827433 0.763470765 0.052622902 0.054817555 3.157049462 0.005582484 0.021510348 1.98E-05 4.702989222 -0.227215074 SSS(ph)LIQLTSQNS(ph)SPNQQR ddPTM_HeLa_Curcumin_4h_R1 1 SSSLIQLTSQNSSPNQQR 18 0 O95639;H7C419 O95639 CPSF4 Cleavage and polyadenylation specificity factor subunit 4 2 0 S(0.331)S(0.152)S(0.517)LIQLT(0.001)S(0.001)QNS(0.509)S(0.489)PNQQR 170 2.49E-05 3223000 1208.4 729.38 646.69 945.86 1000.4 1561.6 932.47 844.74 1096.3 718.3 TRUE FALSE FALSE 1112.753865 792.4243571 670.6569003 941.9462819 988.4708834 1237.706557 958.6325986 1102.297337 976.0386328 743.2608715 1.497124237 1.066145666 0.902316974 1.267315848 1.3299111 1.665238417 1.289765996 1.483055788 1.313184469 1 9.53772485 -9.558943981 1.297572796 0.997964572 1.32571644 0 0.225796374 0.55508824 1.657809425 0.161672717 0.037116132 2.76E-10 9.558943981 0.327751868 SSS(ph)LIQLTSQNSS(ph)PNQQR ddPTM_HeLa_Curcumin_4h_R1 1 SSSLIQLTSQNSSPNQQR 18 0 O95639;H7C419 O95639 CPSF4 Cleavage and polyadenylation specificity factor subunit 4 2 0 S(0.011)S(0.015)S(0.974)LIQLT(0.006)S(0.005)QNS(0.444)S(0.545)PNQQR 158.5 9.83E-05 6742400 2666.8 2178.5 2344.7 2446.8 2198.1 3688.4 3026.4 2440.1 2216 2678.4 TRUE FALSE FALSE 2455.719966 2366.799833 2431.596645 2436.67579 2171.889093 2923.384263 3111.312639 3184.075257 1972.910344 2771.474201 0.886069935 0.85398588 0.877365788 0.879198439 0.78365842 1.054812007 1.122620098 1.148874219 0.711863146 1 11.43643786 -5.03957427 6.204812692 0.917898241 1.125727883 0.594319302 0.087217915 0.097022192 10.62634982 0.010440412 0.027892814 9.13E-06 5.03957427 0.207829641 S(ph)EEEQS(ph)SS(ph)SVKK ddPTM_HeLa_Curcumin_4h_R1 1 SEEEQSSSSVKK 12 1 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7 P07910 HNRNPC Heterogeneous nuclear ribonucleoproteins C1/C2 3 0 S(0.894)EEEQS(0.841)S(0.189)S(0.952)S(0.123)VKK 93.228 0.0038571 0 1556.6 1576 1468.4 1522.9 1527.5 2413.2 1973.2 3783.4 1918.5 1390 TRUE FALSE FALSE 1433.393467 1712.222417 1522.820196 1516.598643 1509.28556 1912.675118 2028.562681 4936.941243 1708.04535 1438.302397 0.996586998 1.190446753 1.05876219 1.054436568 1.049352044 1.329814316 1.410386777 3.432477937 1.187542588 1 10.49015131 -3.490319898 1.255252401 1.026624439 14.03791893 0.972573618 0.115904894 0.78287069 0.249456758 0.015283644 21.09609631 0.000323355 3.490319898 13.01129449 up SAS(ph)PSVPGPTKPKPK ddPTM_HeLa_Curcumin_4h_R1 2 SASPSVPGPTKPKPK 15 2 Q03164-2;Q03164;Q03164-3;A0A3B3ITZ6 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 1 0 S(0.174)AS(0.744)PS(0.082)VPGPT(0.001)KPKPK;S(0.025)AS(0.942)PS(0.032)VPGPTKPKPK ; 90.706 0.005161 114927000 13679.5 9558.6 11379.1 13227.2 12167.7 12345.5 9649.4 2998.44 12863.8 9349.3 TRUE FALSE FALSE 12596.75314 10384.80279 11800.81946 13172.46935 12022.60812 9784.904138 9920.136194 3912.650553 11452.67332 9674.187479 1.302099341 1.07345478 1.219825384 1.36160989 1.242751203 1.011444543 1.025423191 0.404442292 1.183838265 1 13.23992478 -4.143793093 1.721351004 1.164245327 2.37E-16 0.812875095 0.110785197 0.525503205 1.194606535 0.020021211 1.097554244 7.18E-05 4.143793093 -1.164245327 down SSS(ph)MAAGLER ddPTM_HeLa_Curcumin_4h_R1 4 SSSMAAGLER 10 0 B4DWA1;I3L4C2;Q9UQB8-3;Q9UQB8-5;Q9UQB8-4;Q9UQB8-2;Q9UQB8;I3L0Y9;I3L3C6;Q9UQB8-6 B4DWA1 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 0 SS(0.004)S(0.996)MAAGLER;S(0.314)S(0.006)S(0.68)MAAGLER;SS(0.002)S(0.998)MAAGLER;SS(0.006)S(0.994)MAAGLER ;;; 172.61 0.0004453 341929600 7034.15 6773.8 7092.37 7463.4 7803.2 10189.7 8071.79 8251.77 7517.3 8118.6 TRUE FALSE FALSE 6477.389605 7359.297089 7355.219471 7432.518428 7710.151936 8076.241358 8298.262703 10767.69669 6692.670997 8400.720746 0.771051652 0.87603163 0.875546241 0.884747708 0.917796481 0.961374816 0.98780366 1.281758674 0.79667819 1 13.03629739 SSS(ph)MS(ph)SIDLVSASDDVHR ddPTM_HeLa_Curcumin_4h_R1 2 SSSMSSIDLVSASDDVHR 18 0 Q9Y5P4;Q9Y5P4-3;A0A0A0MRE4;A0A2R8YFA1;A0A2U3TZL3 Q9Y5P4 COL4A3BP Collagen type IV alpha-3-binding protein 2 0 S(0.096)S(0.119)S(0.782)MS(0.559)S(0.445)IDLVSASDDVHR;S(0.126)S(0.145)S(0.706)MS(0.511)S(0.511)IDLVSASDDVHR ; 103.92 0.0010215 3966500 1510.2 1359.93 1551.63 1706.64 1466.06 2840.8 2103.88 2259.25 1976.73 1777.66 TRUE FALSE FALSE 1390.666076 1477.476289 1609.134773 1699.578376 1448.578192 2251.586058 2162.90921 2948.084925 1759.887665 1839.433553 0.756029526 0.803223518 0.874799076 0.923968345 0.787513194 1.224064905 1.175856126 1.602713466 0.956755226 1 10.84504585 -4.28068911 0.935849427 0.871095829 1.949883102 0.829344573 0.10203036 0.665713399 0.444657072 0.018196965 0.722631423 5.24E-05 4.28068911 1.078787273 SSS(ph)MSSLTGAYTSGIPSSSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSMSSLTGAYTSGIPSSSR 20 0 A8CG34-2;A8CG34 A8CG34-2 POM121C Nuclear envelope pore membrane protein POM 121C 1 0 S(0.002)S(0.032)S(0.831)MS(0.113)S(0.021)LTGAYTSGIPSSSR 105.14 0.00040476 7698700 1299.7 772.89 912.19 889.13 1032 1095.1 818.56 444.61 1403 820.63 TRUE FALSE FALSE 1196.827374 839.6951677 945.9965638 885.4510156 1019.694074 867.9639157 841.5265906 580.1695423 1249.09441 849.1468314 1.409446905 0.988869223 1.114055342 1.042753718 1.200845409 1.022159989 0.991026003 0.683238188 1.470999318 1 9.729870231 -3.75888791 0.786027366 1.170032631 1.56E-10 0.491831396 0.152962826 3.591340703 0.926303201 0.026644257 4.427747731 0.000174226 3.75888791 -1.17003263 SSS(ph)MSYVDGFIGTWPK ddPTM_HeLa_Curcumin_4h_R1 1 SSSMSYVDGFIGTWPK 16 0 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 0 SS(0.017)S(0.861)MS(0.122)YVDGFIGTWPK 321.82 1.39E-112 121500000 3971.7 3051.7 3842.1 3342.3 3402.7 4562.1 3840.8 4702.8 3359.7 3469.3 TRUE FALSE FALSE 3657.335754 3315.47535 3984.491606 3328.470448 3362.125025 3615.869035 3948.562511 6136.662071 2991.149316 3589.857917 1.018796799 0.923567291 1.109930169 0.927187238 0.936562143 1.007245723 1.099921669 1.709444277 0.833222201 1 11.80971103 -4.24660282 2.925653599 0.999498748 1.84520794 0.896827185 0.074416201 0.064738483 0.762490704 0.006914412 0.130569716 5.67E-05 4.24660282 0.845709192 SSS(ph)PAGETEGDREPQAR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPAGETEGDREPQAR 17 1 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 0 S(0.306)S(0.306)S(0.389)PAGETEGDREPQAR 88.283 0.0022539 32322000 2613.7 2374.8 2716.5 2704.9 2789.8 2360.3 2425.9 1611.7 2243.8 2272.7 TRUE FALSE FALSE 2406.822887 2580.06713 2817.17588 2693.707841 2756.533457 1870.747174 2493.964225 2103.099911 1997.660754 2351.676156 1.023449968 1.097118378 1.197943804 1.14544166 1.17215691 0.795495234 1.060504959 0.894298267 0.84946252 1 11.19947369 -5.265899564 24.99966139 1.051934335 0.931140037 0.265708187 0.112939342 422.4942759 2368118.404 0.014634997 0.033773016 5.42E-06 5.265899564 -0.120794298 SSS(ph)PAPADIAQTVQEDLR ddPTM_HeLa_Curcumin_4h_R1 25 SSSPAPADIAQTVQEDLR 18 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 0 S(0.004)S(0.004)S(0.992)PAPADIAQTVQEDLR;S(0.3)S(0.013)S(0.688)PAPADIAQTVQEDLR;S(0.012)S(0.012)S(0.977)PAPADIAQTVQEDLR;S(0.001)S(0.001)S(0.998)PAPADIAQTVQEDLR;SS(0.008)S(0.992)PAPADIAQTVQEDLR;S(0.047)S(0.047)S(0.906)PAPADIAQTVQEDLR;SSS(1)PAPADIAQTVQEDLR;S(0.132)S(0.047)S(0.822)PAPADIAQTVQEDLR;S(0.016)S(0.024)S(0.959)PAPADIAQTVQEDLR;S(0.166)S(0.166)S(0.669)PAPADIAQTVQEDLR;S(0.004)S(0.039)S(0.958)PAPADIAQTVQEDLR;S(0.001)S(0.019)S(0.98)PAPADIAQTVQEDLR;S(0.003)S(0.003)S(0.994)PAPADIAQTVQEDLR;S(0.001)S(0.016)S(0.983)PAPADIAQTVQEDLR;SS(0.023)S(0.977)PAPADIAQTVQEDLR;S(0.001)S(0.001)S(0.999)PAPADIAQTVQEDLR;S(0.001)S(0.024)S(0.975)PAPADIAQTVQEDLR;S(0.002)S(0.002)S(0.996)PAPADIAQTVQEDLR;S(0.221)S(0.022)S(0.756)PAPADIAQTVQEDLR;SS(0.037)S(0.963)PAPADIAQTVQEDLR;S(0.001)S(0.001)S(0.997)PAPADIAQTVQEDLR;SS(0.03)S(0.97)PAPADIAQTVQEDLR;SS(0.024)S(0.976)PAPADIAQTVQEDLR;SS(0.095)S(0.905)PAPADIAQTVQEDLR;SS(0.034)S(0.965)PAPADIAQTVQEDLR ;;;;;;;;;;;;;;;;;;;;;;;; 378.44 3.06E-222 37057602800 56249.91 54451.94 48750.65 54189.05 47774.59 55454.48 43199.65 39241.53 63687.14 54618.16 TRUE FALSE FALSE 51797.67027 59158.52306 50557.39197 53964.83007 47204.90922 43952.59575 44411.71591 51206.09185 56700.82008 56516.13699 0.91651116 1.046754541 0.8945656 0.954857019 0.835246564 0.777699929 0.78582363 0.906043735 1.003267794 1 15.78637524 -5.743695777 3.991390806 0.961545059 0.817207656 0.639927695 0.052407327 0.107267395 3.770988829 0.007789424 0.015538542 1.80E-06 5.743695777 -0.144337403 SSS(ph)PATEQSWMENDFDELR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPATEQSWMENDFDELR 19 0 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 0 S(0.108)S(0.108)S(0.498)PAT(0.286)EQSWMENDFDELR 118.23 0.00026065 4126700 1152.5 1061.1 1270.6 960.6 1363.5 1459.5 1331 698.81 994.41 1091.3 TRUE FALSE FALSE 1061.278409 1152.816756 1317.689554 956.6252917 1347.241153 1156.783248 1368.344278 911.8739521 885.3257109 1129.222594 0.939831008 1.020894164 1.166899742 0.847153871 1.193069604 1.024406751 1.211757793 0.807523651 0.784013458 1 10.14111418 -7.008751327 24.51711551 0.97204874 1.05069233 0.106182045 0.140763596 619.9759811 1736888.295 0.018699251 0.023897336 9.80E-08 7.008751327 0.07864359 SSS(ph)PATEQSWMENDFDELREEGFR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPATEQSWMENDFDELREEGFR 24 1 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 0 S(0.045)S(0.045)S(0.691)PAT(0.181)EQS(0.038)WMENDFDELREEGFR 62.303 0.0018602 16692000 613.69 519.93 498.02 362.47 642.32 497.67 499.87 366.37 587.56 454.41 TRUE FALSE FALSE 565.1157889 564.8704324 516.4770593 360.9701952 634.6607535 394.4476321 513.8950069 478.0745264 523.106138 470.2007137 1.201860764 1.201338952 1.09841828 0.767693848 1.349765611 0.838892032 1.092926897 1.016745642 1.112516682 1 8.877132919 -6.485824554 24.99724059 1.10803027 1.017288461 0.107829221 0.154785858 1250.078569 843319.5785 0.023542585 0.035955941 3.27E-07 6.485824554 -0.09074181 SSS(ph)PATEQSWMENDFDELREEGFRR ddPTM_HeLa_Curcumin_4h_R1 3 SSSPATEQSWMENDFDELREEGFRR 25 2 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 0 S(0.383)S(0.121)S(0.433)PAT(0.054)EQS(0.009)WMENDFDELREEGFRR;S(0.097)S(0.097)S(0.741)PAT(0.049)EQS(0.017)WMENDFDELREEGFRR;S(0.135)S(0.135)S(0.566)PAT(0.164)EQSWMENDFDELREEGFRR ;; 65.374 0.00044338 37590100 3437.28 2731.21 3195.31 3413.46 3007.1 3924.3 3113.72 2490.85 4022.4 3240.45 TRUE FALSE FALSE 3165.215661 2967.283622 3313.730999 3399.336007 2971.242297 3110.355944 3201.082603 3250.298699 3581.152784 3353.055396 0.943979531 0.88494918 0.988272071 1.013802519 0.886129797 0.927618419 0.954676325 0.96935431 1.068026728 1 11.7112606 -9.085659113 0.897124865 0.999526872 0.945846018 0.325289306 0.044491803 0.716919744 1.060177468 0.024322151 0.007527903 8.21E-10 9.085659113 -0.053680854 SSS(ph)PCRTPEPDNDAHLR ddPTM_HeLa_Curcumin_4h_R1 2 SSSPCRTPEPDNDAHLR 17 1 Q9Y2K6 Q9Y2K6 USP20 Ubiquitin carboxyl-terminal hydrolase 20 1 0 S(0.126)S(0.126)S(0.586)PCRT(0.161)PEPDNDAHLR;S(0.139)S(0.139)S(0.583)PCRT(0.139)PEPDNDAHLR ; 97.823 0.00098 13616000 5047.9 5162.3 5049.6 5539.8 4809.5 5806.3 4073.4 3135.4 6009.8 5712.4 TRUE FALSE FALSE 4648.353388 5608.506209 5236.742618 5516.877775 4752.149854 4602.00793 4187.688641 4091.369026 5350.539976 5910.905475 0.786402931 0.94884045 0.885945925 0.93333886 0.803963094 0.778562261 0.708468213 0.692172975 0.905198027 1 12.52916343 -1 0.058533836 1.228540182 7.14E-14 0.57049482 0.065351425 211.2139788 0.934730737 4.140039508 22.4148662 0.1 1 -1.228540182 SSS(ph)PEDPGAEV ddPTM_HeLa_Curcumin_4h_R1 2 SSSPEDPGAEV 11 0 Q9Y5U2-2;Q9Y5U2 Q9Y5U2-2 TSSC4 Protein TSSC4 1 0 S(0.012)S(0.012)S(0.976)PEDPGAEV;S(0.008)S(0.008)S(0.984)PEDPGAEV ; 144.77 0.0010255 21649000 6537.4 5305.7 5302.2 5361.1 5818.3 5695.4 4600 4704.1 5537 5309.9 TRUE FALSE FALSE 6019.957892 5764.301066 5498.704196 5338.917189 5748.920573 4514.10984 4729.06362 6138.358435 4929.604953 5494.41863 1.095649658 1.04911938 1.000779985 0.97169829 1.046320086 0.821580979 0.860703186 1.117198897 0.897202286 1 12.42375112 -6.018813717 1.29226327 1.045355645 0.938254548 0 0.094024841 0.486285985 1.609714933 0.013616984 0.030252613 9.58E-07 6.018813717 -0.107101097 S(ph)GSPAPETTNESVPFAQHSSLDSR ddPTM_HeLa_Curcumin_4h_R1 1 SGSPAPETTNESVPFAQHSSLDSR 24 0 O15047 O15047 SETD1A Histone-lysine N-methyltransferase SETD1A 1 0 S(0.858)GS(0.141)PAPET(0.001)TNESVPFAQHSSLDSR 110.33 1.13E-06 11501000 1300 1083 1151.4 1138.1 1114.1 1995 1365.9 2213.2 1280.3 1292.5 TRUE FALSE FALSE 1197.103628 1176.609694 1194.071897 1133.390844 1100.815085 1581.214512 1404.223478 2887.994492 1139.854293 1337.414279 0.895088117 0.879764567 0.892821257 0.847449337 0.823092068 1.182292231 1.049954005 2.159386615 0.852282132 1 10.38523071 -3.424574062 1.319490044 0.92945784 9.280791892 0.931983529 0.099629389 1.795904796 0.509838902 0.014225134 34.31734823 0.000376206 3.424574062 8.351334052 up SSS(ph)PELVTHLKWDDPYYDIAR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPELVTHLKWDDPYYDIAR 21 1 E9PNR6;H0YE29;Q07960 E9PNR6 ARHGAP1 Rho GTPase-activating protein 1 1 0 S(0.076)S(0.076)S(0.832)PELVT(0.015)HLKWDDPYYDIAR 72.271 0.0010186 3906100 2158.1 1250.9 1381 1822.4 1061.4 2679.3 1497.3 5560.9 3217 2599.3 TRUE FALSE FALSE 1987.284108 1359.022222 1432.181075 1814.859392 1048.743498 2123.582978 1539.310208 7256.392811 2864.103149 2689.625482 0.738870196 0.505283071 0.532483457 0.674762864 0.389921759 0.789545977 0.572313959 2.697919417 1.064870618 1 11.39318958 -4.258068787 24.99854894 0.759743221 2.69792014 0.888554353 0.21158128 85.57699337 634666.3566 0.032459107 0.315076915 5.52E-05 4.258068787 1.938176919 SSS(ph)PGKLLGSGYGGLTGGSSR ddPTM_HeLa_Curcumin_4h_R1 2 SSSPGKLLGSGYGGLTGGSSR 21 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 0 S(0.133)S(0.133)S(0.733)PGKLLGSGYGGLTGGSSR;S(0.01)S(0.01)S(0.979)PGKLLGSGYGGLTGGSSR ; 139.43 0.00012246 144158000 5425.5 3939.5 3812.3 4532.5 2965.18 4995.9 3422.1 2938 6590.4 5986.9 TRUE FALSE FALSE 4996.06595 4280.012826 3953.587192 4513.745716 2929.822165 3959.694025 3518.114916 3833.782675 5867.449608 6194.944329 0.806474713 0.690888021 0.638195758 0.72861764 0.47293761 0.639181535 0.567900974 0.618856679 0.947135163 1 12.5968756 -7.638118729 0.457525317 1.000839242 0.567467674 0.85202623 0.060236848 0.200602535 0.107893684 0.031085282 0.025938079 2.30E-08 7.638118729 -0.433371569 SSS(ph)PGKPQAVSSLNSSHSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPGKPQAVSSLNSSHSR 19 1 Q9UHB7;Q9UHB7-2;Q9UHB7-3 Q9UHB7 AFF4 AF4/FMR2 family member 4 1 0 S(0.136)S(0.136)S(0.727)PGKPQAVSSLNSSHSR 99.371 0.00040367 12033000 3457.8 2585.2 1849.5 1880.7 4930.6 10532 3735.8 2333.8 4349.7 2559.2 TRUE FALSE FALSE 3184.111481 2808.653169 1918.044097 1872.918162 4871.805815 8347.54448 3840.616494 3045.364877 3872.548792 2648.13201 1.202399076 1.060616751 0.724300786 0.70726012 1.839714107 3.152238805 1.450311571 1.150004934 1.462369995 1 11.37075933 -5.679512436 6.804199882 1.04041211 1.96751358 0.396168541 0.525712752 0.161947364 11.10539605 0.074020836 0.148515762 2.09E-06 5.679512436 0.927101471 SSS(ph)PHDKNLPQK ddPTM_HeLa_Curcumin_4h_R1 1 SSSPHDKNLPQK 12 1 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 0 S(0.067)S(0.218)S(0.715)PHDKNLPQK 77.372 0.012036 19434000 7763.4 6500.2 4811.6 5592.7 7743.3 11904 6021.2 4624.9 10705 7561.3 TRUE FALSE FALSE 7148.918698 7062.048324 4989.922129 5569.558889 7650.966205 9434.976214 6190.138667 6035.01072 9530.688283 7824.054612 0.913710225 0.902607238 0.637766782 0.711850717 0.977877403 1.205893451 0.79116762 0.771340567 1.218126503 1 12.93370073 -8.027973953 1.139115141 0.980549815 0.862595845 0.187993687 0.166620868 0.785425683 2.134138344 0.041565193 0.033668497 9.38E-09 8.027973953 -0.11795397 NSITEIS(ph)DNEDDLLEYHR ddPTM_HeLa_Curcumin_4h_R1 4 NSITEISDNEDDLLEYHR 18 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 0 NSITEIS(1)DNEDDLLEYHR;NSITEIS(1)DNEDDLLEYHR;NSIT(0.003)EIS(0.997)DNEDDLLEYHR;NSITEIS(1)DNEDDLLEYHR ;;; 212.06 1.96E-13 32464600 10145.4 8248.6 8387.3 8564.9 9577.5 10697.9 8288.8 2398.35 8178.1 9531.7 TRUE FALSE FALSE 9342.380885 8961.572229 8698.140716 8529.460713 9463.294568 8479.03495 8521.36142 3129.595874 7280.982891 9862.925866 0.947222053 0.908611942 0.881902676 0.864800246 0.959481466 0.859687588 0.86397906 0.317309074 0.738217339 1 13.26779997 -4.143541503 2.006485706 0.949152469 7.23E-16 0.799588455 0.082865967 0.225976517 0.741716426 0.008321406 0.434952718 7.19E-05 4.143541503 -0.949152469 down SSS(ph)PPILTKPTLK ddPTM_HeLa_Curcumin_4h_R1 1 SSSPPILTKPTLK 13 1 A0A3B3ITI3;A0A3B3IS53;A0A3F2YNX6;Q92794 A0A3B3ITI3 KAT6A Histone acetyltransferase KAT6A 1 0 S(0.168)S(0.168)S(0.665)PPILTKPTLK 72.662 0.01394 26147000 3479.2 3098 3447.5 3058 3765.5 4061 3709.5 2452.7 2884.5 2794.7 TRUE FALSE FALSE 3203.817649 3365.777316 3575.267383 3045.346806 3720.598872 3218.702823 3813.578586 3200.516939 2568.077567 2891.815617 1.107891399 1.163897621 1.236340022 1.053091625 1.286596161 1.113038744 1.318748873 1.106750002 0.888050245 1 11.49775985 -8.037368176 0.44158463 0.991325408 1.204106246 0.514483304 0.086808954 0.59441698 0.283458077 0.051806358 0.029363577 9.18E-09 8.037368176 0.212780838 SSS(ph)PRGEASSLNGESH ddPTM_HeLa_Curcumin_4h_R1 1 SSSPRGEASSLNGESH 16 1 Q8IY57-3;Q8IY57;Q8IY57-5 Q8IY57-3 YAF2 YY1-associated factor 2 1 0 S(0.084)S(0.084)S(0.832)PRGEASSLNGESH 108.23 0.016827 12354000 1934.4 1500.6 1518.6 1751.6 1844.4 2505.7 1533.2 1240.2 2265.2 1655.8 TRUE FALSE FALSE 1781.290199 1630.305177 1574.880652 1744.352343 1822.406735 1985.989575 1576.217466 1618.331271 2016.713227 1713.338927 1.039660146 0.95153688 0.919188041 1.018101157 1.063658046 1.1591341 0.91996828 0.944548242 1.177066134 1 10.74259485 SSS(ph)PSASLTENEVK ddPTM_HeLa_Curcumin_4h_R1 3 SSSPSASLTENEVK 14 0 O96028-5 O96028-5 WHSC1 Histone-lysine N-methyltransferase NSD2 1 0 S(0.072)S(0.072)S(0.855)PSASLTENEVK;SS(0.08)S(0.897)PS(0.023)ASLTENEVK;S(0.002)S(0.05)S(0.888)PS(0.05)AS(0.01)LTENEVK ;; 227.92 2.37E-20 103538000 15686.6 12093.3 14039.7 16497.3 15142.6 19932.3 13359.4 7390.8 19558.8 14918 TRUE FALSE FALSE 14444.98906 13138.59097 14560.02363 16429.03854 14962.03438 15798.1163 13734.22881 9644.220897 17413.24857 15436.39939 0.935774509 0.851143498 0.943226673 1.064305097 0.969269712 1.023432725 0.889730076 0.624771403 1.128064138 1 13.91404866 -4.297528627 3.024614652 0.968246073 0.583471842 0.681948737 0.073956077 0.118924131 1.65816713 0.007988869 0.104615506 5.04E-05 4.297528627 -0.384774231 SSS(ph)PTAGPSTEGAEGPEEK ddPTM_HeLa_Curcumin_4h_R1 2 SSSPTAGPSTEGAEGPEEK 19 0 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;A0A0C4DGG3 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 0 S(0.003)S(0.003)S(0.993)PTAGPSTEGAEGPEEK;S(0.063)S(0.212)S(0.719)PT(0.006)AGPSTEGAEGPEEK ; 292.19 4.49E-83 42483000 5964 4588.6 5383.9 4940.3 4963.1 5762.7 3937.6 3389 5397.8 3859.3 TRUE FALSE FALSE 5491.943107 4985.218138 5583.43207 4919.858348 4903.918274 4567.451061 4048.078458 4422.290499 4805.674845 3993.410388 1.37525137 1.248361088 1.398161353 1.231994178 1.228002584 1.143746978 1.01368957 1.107396954 1.203401198 1 11.96340562 -4.989473963 4.268561996 1.210201082 1.061432222 0.291309293 0.106598213 0.314203687 13.81808318 0.022028011 0.067107356 1.02E-05 4.989473963 -0.14876886 SSS(ph)PTLTPSQEGSPVFAGFEGR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPTLTPSQEGSPVFAGFEGR 22 0 P0C860 P0C860 MSL3P1 Putative male-specific lethal-3 protein-like 2 1 0 S(0.007)S(0.007)S(0.545)PT(0.429)LT(0.012)PSQEGSPVFAGFEGR 150.98 3.89E-06 4494100 1025 882.92 919.27 1160 1060.9 981.2 731.47 539.51 1162.8 910.47 TRUE FALSE FALSE 943.8701684 959.2356706 953.3389549 1155.200227 1048.24946 777.6880596 751.9930795 704.0041154 1035.243749 942.1087647 1.001869639 1.01817933 1.011920269 1.226185628 1.11266289 0.825475878 0.798201978 0.747264161 1.098857996 1 9.879749816 -5.137867508 5.154558232 1.026593667 0.782130312 0.728997807 0.074829109 0.104953105 3.974284599 0.011276456 0.029709721 7.28E-06 5.137867508 -0.244463355 SSS(ph)PTQYGLTK ddPTM_HeLa_Curcumin_4h_R1 1 SSSPTQYGLTK 11 0 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 0 S(0.157)S(0.298)S(0.545)PTQYGLTK 195.77 1.94E-05 136180000 4477 3055.1 2980 3409.7 3573 3629.1 3252.5 1748.3 3779.7 3208.8 TRUE FALSE FALSE 4122.640726 3319.169231 3090.441421 3395.591565 3530.394309 2876.383752 3343.756396 2281.348622 3365.076366 3320.305561 1.241644978 0.999657763 0.930770185 1.02267442 1.06327392 0.866300917 1.007062855 0.687089962 1.013483941 1 11.6971003 -3.242312472 0.461537299 1.099595459 1.44E-10 0.452247445 0.099542888 7.104743875 0.509972414 0.025797695 5.263697322 0.000572384 3.242312472 -1.099595459 SSS(ph)PTSYWK ddPTM_HeLa_Curcumin_4h_R1 2 SSSPTSYWK 9 0 Q92614;A0A0D9SFK2;Q92614-2;Q92614-3;Q92614-4;Q92614-5 Q92614 MYO18A Unconventional myosin-XVIIIa 1 0 S(0.004)S(0.067)S(0.922)PT(0.005)S(0.002)YWK;S(0.014)S(0.074)S(0.862)PT(0.039)S(0.011)YWK ; 128.35 0.0041784 36111000 10048.9 7859.7 8986.6 8639 9043.4 10030.2 8401.3 13792.4 9220.7 7710.8 TRUE FALSE FALSE 9253.518961 8539.057446 9319.651301 8603.254107 8935.563361 7949.823456 8637.017867 17997.63927 8209.212279 7978.749726 1.15977055 1.070225003 1.16805911 1.078270958 1.119920247 0.996374586 1.082502668 2.25569668 1.028884545 1 12.96194698 -4.261451324 11.11391057 1.080864157 2.257156152 0.975106245 0.056439247 0.008187691 58.24056192 0.009326486 0.071962878 5.48E-05 4.261451324 1.176291995 SSS(ph)PVGLAK ddPTM_HeLa_Curcumin_4h_R1 1 SSSPVGLAK 9 0 B1AKL4;Q9NRA8;Q9NRA8-3;Q9NRA8-2 B1AKL4 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 0 S(0.034)S(0.383)S(0.583)PVGLAK 112.36 0.0083888 52087000 7978 6419.3 6550.2 7216.1 7285.8 7948.3 5764.8 3692.2 7996.2 6800.8 TRUE FALSE FALSE 7346.532882 6974.155688 6792.956174 7186.24169 7198.921594 6299.732984 5926.544773 4817.934783 7119.036866 7037.127294 1.043967599 0.991051518 0.965302444 1.021189669 1.022991527 0.895213732 0.842182403 0.684645109 1.011639632 1 12.78077089 -4.330443683 0.952899444 1.016875308 0.532785986 0.937481835 0.026512844 0.322500015 0.237464402 0.004538602 0.156301085 4.67E-05 4.330443683 -0.484089322 SSS(ph)PVQVEEEPVR ddPTM_HeLa_Curcumin_4h_R1 2 SSSPVQVEEEPVR 13 0 A0A0J9YVR0;Q8IZ21-3;Q8IZ21;Q8IZ21-2 A0A0J9YVR0;Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 0 S(0.006)S(0.006)S(0.988)PVQVEEEPVR;S(0.062)S(0.062)S(0.875)PVQVEEEPVR ; 271.43 3.66E-47 618550000 7023.9 5512.1 5398.6 5664 4709.1 5222.2 3045.9 2301.3 6955.1 5357.5 TRUE FALSE FALSE 6467.950903 5988.541363 5598.676865 5640.563869 4652.947058 4139.056854 3131.359756 3002.955776 6192.142931 5543.672726 1.166726685 1.080247998 1.009921967 1.017477789 0.839325712 0.746627202 0.564852925 0.541690667 1.116974835 1 12.43662637 -5.258346507 0.972451753 1.079751585 0.50142125 0.951601962 0.046864995 0.142933862 0.221159345 0.0107541 0.059841156 5.52E-06 5.258346507 -0.578330335 SSS(ph)PVTELAS(ph)RSPIR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPVTELASRSPIR 15 1 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(0.018)S(0.023)S(0.956)PVT(0.124)ELAS(0.674)RS(0.205)PIR 101.04 0.014397 17175000 3118 2583.8 3433.2 3161.7 3668.8 3875.5 3141.2 3487 3619.9 3194.8 TRUE FALSE FALSE 2871.20701 2807.132159 3560.437412 3148.617723 3625.051956 3071.677614 3229.333618 4550.170248 3222.806027 3305.819062 0.868531204 0.84914876 1.07702126 0.952447083 1.096566959 0.929172939 0.976863391 1.376412369 0.974888815 1 11.69079205 -4.261746014 4.759324832 0.952149508 1.400490156 0.71922734 0.075757315 0.076060608 4.827794489 0.011411078 0.112689992 5.47E-05 4.261746014 0.448340648 SSS(ph)PVTELASR ddPTM_HeLa_Curcumin_4h_R1 3 SSSPVTELASR 11 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.035)S(0.035)S(0.93)PVTELASR;S(0.062)S(0.062)S(0.876)PVTELASR;SS(0.079)S(0.916)PVT(0.004)ELASR ;; 231.17 1.09E-16 438830000 12626.2 11519.6 12551.2 12159 14127.5 14602.9 13425.8 15518.5 11715.3 10270.9 TRUE FALSE FALSE 11626.82295 12515.30289 13016.35851 12108.68928 13959.03879 11574.09393 13802.49181 20250.01921 10430.1609 10627.81301 1.093999578 1.177599087 1.224744781 1.139339699 1.313444147 1.089038161 1.298714213 1.905379704 0.981402372 1 13.37555713 -1.194887461 0.851870287 1.08234462 200 0.84239541 0.099747527 127.8849374 0.486343676 0.01690115 49109.11066 0.06384289 1.194887461 198.9176554 SSS(ph)QENLLDEVMK ddPTM_HeLa_Curcumin_4h_R1 5 SSSQENLLDEVMK 13 0 Q3V6T2;Q3V6T2-3;Q3V6T2-2;Q3V6T2-4;Q3V6T2-5;A0A2U3TZV9;A0A2R8Y7B1;A0A2R8Y7D4;H7C2C6;A0A2R8Y820;A0A2R8Y885;A0A2R8YCU9;A0A2R8YDS8;H0Y470;H0Y7U8;A0A2R8Y5D7;H0Y7K3;A0A2R8Y4Z5;A0A2R8Y4C6 Q3V6T2 CCDC88A Girdin 1 0 S(0.004)S(0.105)S(0.891)QENLLDEVMK;S(0.004)S(0.11)S(0.886)QENLLDEVMK;S(0.002)S(0.089)S(0.909)QENLLDEVMK;S(0.001)S(0.027)S(0.972)QENLLDEVMK;S(0.327)S(0.032)S(0.641)QENLLDEVMK ;;;; 226.06 2.67E-19 77632800 22071.5 19837.9 17163.8 18315.1 17199.3 21974 16858.6 10283.8 25544.4 18940.3 TRUE FALSE FALSE 20324.51749 21552.59968 17799.90553 18239.31697 16994.20958 17416.3447 17331.60694 13419.28328 22742.24323 19598.47402 1.037045918 1.099708052 0.908229157 0.930649853 0.86711902 0.888658203 0.884334511 0.684710619 1.160408877 1 14.25845371 -2.955436357 0.375795724 1.024655422 3.15E-13 0.710521957 0.068912159 5.112749191 0.235699835 0.015354609 2.925169554 0.001108061 2.955436357 -1.024655422 SSS(ph)QGPLSSIR ddPTM_HeLa_Curcumin_4h_R1 1 SSSQGPLSSIR 11 0 A0A0U1RQE4 A0A0U1RQE4 1 0 S(0.221)S(0.024)S(0.755)QGPLSSIR 148.89 0.00071775 13140000 4522.1 3674.9 4213.7 4252.1 3959.1 4985.4 4378.9 2817.9 4509.6 4297.5 TRUE FALSE FALSE 4164.171013 3992.541981 4369.863429 4234.505937 3911.890318 3951.371843 4501.760149 3677.064738 4014.908162 4446.837805 0.936434202 0.897838454 0.982690087 0.952251043 0.879701597 0.888580159 1.012350876 0.826894278 0.902868137 1 12.11856407 -13.52287875 0.133641943 1.274139608 0.890772305 0 0.057936385 73.98743777 0.69644027 5.350147371 0.156533981 3.00E-14 13.52287875 -0.383367304 SSS(ph)RQLS(ph)ES(ph)FKS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SSSRQLSESFKSK 13 2 Q08945 Q08945 SSRP1 FACT complex subunit SSRP1 4 0 S(0.264)S(0.328)S(0.408)RQLS(1)ES(1)FKS(1)K 74.789 0.0084386 8670000 2099.9 2499.7 2900.5 2314.5 2051.9 1781.5 2071.9 1893.5 3256.5 2814.2 TRUE FALSE FALSE 1933.690699 2715.76293 3007.995082 2304.923212 2027.432433 1411.996818 2130.031938 2470.819433 2899.270097 2911.993241 0.664043677 0.932613061 1.032967742 0.791527666 0.696235281 0.484890143 0.73146871 0.848497654 0.995630779 1 11.50779129 -5.865517189 4.001639882 0.860394393 0.678303055 0.357488668 0.134757262 0.269353848 8.015506043 0.024102201 0.045435972 1.36E-06 5.865517189 -0.182091338 SSS(ph)RSSSPS(ph)S(ph)S(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SSSRSSSPSSSR 12 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 4 0 S(0.102)S(0.123)S(0.755)RS(0.009)S(0.009)S(0.01)PS(0.998)S(0.997)S(0.997)R 52.891 0.0096734 0 3009.7 2599 2820.4 3284.2 3324.3 127.88 559.89 831.96 2663.5 2571.4 TRUE FALSE FALSE 2771.479069 2823.645979 2924.926505 3270.610851 3284.659894 101.3562465 575.5990065 1085.620774 2371.320714 2660.755959 1.041613403 1.061219452 1.099284019 1.229203618 1.234483712 0.038093026 0.216329124 0.408012156 0.891220672 1 11.37762048 -5.26167568 24.99999978 1.05791002 0.220363177 0.905067539 0.127317717 4.283041591 453168.3511 0.01755434 0.041706811 5.47E-06 5.26167568 -0.837546843 SSS(ph)SERPEPQQK ddPTM_HeLa_Curcumin_4h_R1 1 SSSSERPEPQQK 12 1 P78362;C9J2M4 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 0 S(0.001)S(0.004)S(0.993)S(0.002)ERPEPQQK 153.81 0.003662 7535900 2753.7 2385.4 2419.5 1989.7 2436.7 2445.7 1984.5 1947.3 2398.4 2305 TRUE FALSE FALSE 2535.741739 2591.583347 2509.168798 1981.467149 2407.643944 1938.434251 2040.179729 2541.022806 2135.301521 2385.098578 1.06316014 1.086572845 1.052018907 0.830769498 1.009452593 0.8127271 0.855385915 1.065374332 0.895267617 1 11.21983318 -6.281745799 24.59318159 1.037255246 0.911038549 0.249008245 0.088079531 485.8215185 588379.1458 0.011256625 0.017208504 5.23E-07 6.281745799 -0.126216698 SSS(ph)SGDQSSDSLNSPTLLAL ddPTM_HeLa_Curcumin_4h_R1 1 SSSSGDQSSDSLNSPTLLAL 20 0 P15408;P15408-3;P15408-2 P15408 FOSL2 Fos-related antigen 2 1 0 S(0.074)S(0.122)S(0.682)S(0.122)GDQSSDSLNSPTLLAL 233.57 1.23E-25 1126700 287.4 344.03 275.83 329.92 307.51 642.8 470.08 190.01 342.26 230.37 TRUE FALSE FALSE 264.6519867 373.7664202 286.0525024 328.5548785 303.8431441 509.4760342 483.2691796 247.9431743 304.7149343 238.3753404 1.110232234 1.567974354 1.200008785 1.378309006 1.274641679 2.137284978 2.027345525 1.040137683 1.278298896 1 7.897091188 -6.515104478 0.553948755 1.01743415 1.723915805 0.221751977 0.331236857 0.649337409 0.404471943 0.085913758 0.190770523 3.05E-07 6.515104478 0.706481655 ASYDVSDSGQLEHVQPWS(ph)V ddPTM_HeLa_Curcumin_4h_R1 2 ASYDVSDSGQLEHVQPWSV 19 0 Q01813;Q01813-2;B1APP6 Q01813 PFKP "ATP-dependent 6-phosphofructokinase, platelet type" 1 0 ASYDVSDSGQLEHVQPWS(1)V;ASYDVSDSGQLEHVQPWS(1)V ; 161.75 1.63E-05 22475300 3924.71 3676.16 4255.32 3729.82 4088.48 8159.7 5563.7 6958.2 4614.5 4306.7 TRUE FALSE FALSE 3614.065062 3993.91089 4413.025903 3714.386993 4039.727546 6467.286241 5719.802448 9079.723148 4108.300895 4456.357504 0.810990828 0.896227667 0.990276453 0.83350292 0.906508857 1.451249419 1.283515167 2.037476378 0.921896614 1 12.12164926 -3.41310163 0.704219231 0.902409188 4.838730911 0.878949308 0.126476351 1.924788426 0.28303418 0.02152267 7.999194068 0.000386277 3.41310163 3.936321723 up NS(ph)PATPPNTLNLR ddPTM_HeLa_Curcumin_4h_R1 1 NSPATPPNTLNLR 13 0 Q92870;Q92870-4;H0YAJ5;G5E9Y1;Q92870-2;D6RDY3;D6RB00;D6RB55 Q92870 APBB2 Amyloid beta A4 precursor protein-binding family B member 2 1 0 NS(0.854)PAT(0.089)PPNT(0.057)LNLR 106.54 0.0054602 0 2002.6 1453.9 1650 1609.9 1528.2 2055.5 1249.9 507.04 1982 1563.6 TRUE FALSE FALSE 1844.092097 1579.568638 1711.150451 1603.23866 1509.977213 1629.16613 1284.96883 661.6341619 1764.579559 1617.934984 1.139781336 0.976286843 1.057613853 0.990916617 0.933274346 1.006941655 0.794203008 0.408937422 1.090636878 1 10.65993792 -4.142879135 1.176753963 1.049875631 6.96E-19 0.917899396 0.056712843 0.444514391 0.420716144 0.010224443 0.608226452 7.20E-05 4.142879135 -1.049875631 down SSS(ph)SSASPS(ph)SPSSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 0 S(0.287)S(0.129)S(0.584)S(0.001)S(0.001)AS(0.013)PS(0.563)S(0.394)PS(0.006)S(0.024)R 118.71 0.0045281 5420700 3810 4027 4225.4 3670 4483.8 4542.1 2983.9 2415.7 3551.8 3976.2 TRUE FALSE FALSE 3508.43448 4375.075936 4381.997041 3654.814512 4430.333613 3600.01726 3067.620203 3152.235809 3162.176426 4114.372654 0.852726472 1.063364042 1.06504622 0.888304201 1.076794444 0.874985706 0.745586378 0.766152236 0.768568307 1 12.00645675 -4.924096694 4.197325716 0.95545355 0.758227538 0.416660737 0.095450622 0.141522579 4.792009159 0.012126696 0.039165338 1.19E-05 4.924096694 -0.197226012 LSESSAS(ph)PQPK ddPTM_HeLa_Curcumin_4h_R1 3 LSESSASPQPK 11 0 Q8N5Y2;Q8N5Y2-3;Q8N5Y2-2;A0A3B3IT59;Q8N5Y2-6;Q8N5Y2-4;A0A3B3ITL5;A0A3B3ITF3;A0A3F2YNX2;A0A3B3IRN2;A0A3B3IU80;A0A3B3IUB0;A0A3B3IS72;A0A3B3ISB4;A0A3B3IRI6;A0A3B3ITV8;A0A3B3IRT2;A0A3B3ITF8;A0A3B3IT49;Q8N5Y2-5;A0A3B3ITX5 Q8N5Y2 MSL3 Male-specific lethal 3 homolog 1 0 LSES(0.01)S(0.01)AS(0.981)PQPK;LSES(0.023)S(0.056)AS(0.921)PQPK;LSES(0.002)S(0.009)AS(0.989)PQPK ;; 165.35 0.00026931 77902000 15277.7 11510.3 11922.7 13505.6 13563.7 14712.9 11049.1 3466.1 14802.7 11613 TRUE FALSE FALSE 14068.45392 12505.19904 12364.56575 13449.71741 13401.96174 11661.27869 11359.10801 4522.897934 13178.88084 12016.55089 1.170756406 1.040664594 1.028961294 1.119266047 1.115291889 0.970434761 0.945288554 0.37638903 1.09672742 1 13.55273524 -4.142640476 1.760123482 1.07710832 1.83E-16 0.931728945 0.056004873 0.284103304 0.679230255 0.010211835 0.559496198 7.20E-05 4.142640476 -1.07710832 down SSS(ph)SSQESLNRPFSSK ddPTM_HeLa_Curcumin_4h_R1 1 SSSSSQESLNRPFSSK 16 1 E3W994;J3KR49;O75122;E7ERI8;E7EW49;O75122-3;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2 E3W994 CLASP2 CLIP-associating protein 2 1 0 S(0.04)S(0.04)S(0.629)S(0.201)S(0.083)QES(0.007)LNRPFSSK 94.313 0.001917 75391000 5163 4171.6 5256.5 4755.8 5125.7 5092.5 3979.7 3344.5 5700.1 4886.6 TRUE FALSE FALSE 4754.343102 4532.174516 5451.310514 4736.12176 5064.579375 4036.258096 4091.359671 4364.222654 5074.813291 5056.408986 0.940260789 0.896322771 1.078099206 0.936657176 1.001615848 0.79824597 0.809143343 0.863107131 1.003639797 1 12.30389744 -5.26023291 25 0.9725742 0.822063261 0.676640356 0.049257945 47.21053122 978263.6382 0.006792389 0.016322222 5.49E-06 5.26023291 -0.150510939 SSS(ph)SSS(ph)SSSGSEASSEHKR ddPTM_HeLa_Curcumin_4h_R1 1 SSSSSSSSSGSEASSEHKR 19 1 A0A1B0GV45 A0A1B0GV45 2 0 S(0.077)S(0.097)S(0.816)S(0.011)S(0.002)S(0.888)S(0.106)S(0.001)SGS(0.001)EAS(0.001)S(0.001)EHKR 87.647 0.0039709 4834800 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 SSS(ph)T(ph)RSGGGDLTLGLEPSEEEAPR ddPTM_HeLa_Curcumin_4h_R1 1 SSSTRSGGGDLTLGLEPSEEEAPR 24 1 B4DTR1;P04626-3;P04626-2;P04626-5;P04626-4;P04626 B4DTR1 ERBB2 Receptor protein-tyrosine kinase;Receptor tyrosine-protein kinase erbB-2 2 0 S(0.372)S(0.414)S(0.441)T(0.75)RS(0.024)GGGDLTLGLEPSEEEAPR 72.514 0.0012581 2434700 3146.7 2469.2 2377.7 2891.8 2649.7 4043.3 2565.9 2060.2 3651 2611.3 TRUE FALSE FALSE 2897.635375 2682.626645 2465.819654 2879.834498 2618.104058 3204.674003 2637.892248 2688.345496 3250.494434 2702.042481 1.072387054 0.992814386 0.912576198 1.06579912 0.968935195 1.186019104 0.976258614 0.994930877 1.202976806 1 11.39983464 -2.935479826 13.38182951 1.026521407 1.027257791 0 0.090490862 0 0 0.009014288 0 0.001160166 2.935479826 0.000736384 SSS(ph)TEPPPPVR ddPTM_HeLa_Curcumin_4h_R1 1 SSSTEPPPPVR 11 0 Q8N684-2;Q8N684;Q8N684-3;F5H669;F5H6M0;F5H047;F5H5B7;F5H1W4;F5H2K8;F5H6P5;F5H6A8;F5GXA3;C9JM38;C9J286;C9J323;J3QT54 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 0 SS(0.025)S(0.949)T(0.025)EPPPPVR 183.99 0.0001046 54901000 3210.2 2816.9 3283.7 2818.3 2697.4 2623.6 2733.2 2617.3 2936.8 2498 TRUE FALSE FALSE 2956.109283 3060.380284 3405.396811 2806.638621 2665.235267 2079.435786 2809.886236 3415.302721 2614.640388 2584.805314 1.143648718 1.1839887 1.317467429 1.085822056 1.031116445 0.80448449 1.087078482 1.321299791 1.011542484 1 11.33583991 -4.26565261 6.713590423 1.075476967 1.3252781 0.255925925 0.126620849 0.12643188 38.23598457 0.01864003 0.144621877 5.42E-05 4.26565261 0.249801134 SSS(ph)TGNLLDKDDLAIPPPDYGAASR ddPTM_HeLa_Curcumin_4h_R1 2 SSSTGNLLDKDDLAIPPPDYGAASR 25 1 B4DWA1;I3L4C2;Q9UQB8-3;Q9UQB8-5;Q9UQB8-4;Q9UQB8-2;Q9UQB8;I3L3C6;Q9UQB8-6 B4DWA1 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 0 S(0.155)S(0.175)S(0.472)T(0.197)GNLLDKDDLAIPPPDYGAASR;S(0.085)S(0.085)S(0.415)T(0.415)GNLLDKDDLAIPPPDYGAASR ; 66.853 0.0004277 158351000 2450.22 3137.86 2616.53 3112.26 2723.65 3173.1 2471.3 3068.36 4124 3482.07 TRUE FALSE FALSE 2256.282502 3409.082636 2713.500904 3099.382293 2691.172253 2514.963292 2540.638027 4003.888839 3671.607518 3603.071673 0.62621083 0.946160095 0.753107667 0.860205562 0.746910552 0.698005346 0.705131137 1.111243184 1.019021505 1 11.81501164 -9.632820608 1.462477263 0.999692596 0.775636468 0.239575995 0.135861642 0.438890238 1.690386679 0.094925582 0.021741586 2.33E-10 9.632820608 -0.224056128 SSS(ph)TRS(ph)GGGDLTLGLEPSEEEAPR ddPTM_HeLa_Curcumin_4h_R1 1 SSSTRSGGGDLTLGLEPSEEEAPR 24 1 B4DTR1;P04626-3;P04626-2;P04626-5;P04626-4;P04626 B4DTR1 ERBB2 Receptor protein-tyrosine kinase;Receptor tyrosine-protein kinase erbB-2 2 0 S(0.131)S(0.146)S(0.511)T(0.487)RS(0.725)GGGDLT(0.001)LGLEPSEEEAPR 69.576 0.0014664 0 2160.6 1918.5 1981.6 2322.3 1748.4 2297.6 1735.4 1463.9 2521.4 2045.9 TRUE FALSE FALSE 1989.58623 2084.326591 2055.039839 2312.690938 1727.551472 1821.051861 1784.090653 1910.236371 2244.808728 2116.994873 0.939816272 0.984568559 0.970734443 1.0924405 0.816039516 0.86020608 0.842746799 0.902333962 1.060375137 1 11.04780206 -5.737620412 24.99984426 0.979483905 0.85478083 0.668333617 0.050334791 111.0252588 116528.9565 0.006475362 0.012945103 1.83E-06 5.737620412 -0.124703075 AAHVPENS(ph)DTEQDVLTVKPVR ddPTM_HeLa_Curcumin_4h_R1 4 AAHVPENSDTEQDVLTVKPVR 21 1 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 0 AAHVPENS(0.93)DT(0.07)EQDVLTVKPVR;AAHVPENS(0.967)DT(0.033)EQDVLTVKPVR;AAHVPENS(0.993)DT(0.007)EQDVLTVKPVR;AAHVPENS(0.933)DT(0.066)EQDVLT(0.001)VKPVR ;;; 144.33 9.11E-06 62203500 7097.1 5829.52 6268.98 7304 6231.85 7502.1 5171.13 1910.61 6728.4 6489.07 TRUE FALSE FALSE 6535.357046 6333.397733 6501.313914 7273.777983 6157.539259 5946.079894 5316.21799 2493.146194 5990.311354 6714.564699 0.973310607 0.943232811 0.968240564 1.083283624 0.917042211 0.885549572 0.79174425 0.371304218 0.892136962 1 12.71307816 -4.141460471 1.280714374 0.98489989 1.18E-19 0.920067041 0.05245732 0.26778497 0.305966524 0.00623822 0.370066104 7.22E-05 4.141460471 -0.98489989 down SSS(ph)TSDILEPFTVER ddPTM_HeLa_Curcumin_4h_R1 2 SSSTSDILEPFTVER 15 0 A0A1B0GUI1;Q6GYQ0-3;Q6GYQ0-4;Q6GYQ0;Q6GYQ0-7;Q6GYQ0-5;Q6GYQ0-6;Q6GYQ0-2 A0A1B0GUI1 RALGAPA1 Ral GTPase-activating protein subunit alpha-1 1 0 SS(0.002)S(0.998)TSDILEPFTVER;S(0.001)S(0.001)S(0.998)T(0.001)SDILEPFTVER ; 255.39 4.36E-39 175114000 6181.7 5453.1 6060.6 6071.9 5605.9 7106.3 4286.2 4985.2 6923.8 6610.3 TRUE FALSE FALSE 5692.411922 5924.441665 6285.211167 6046.776087 5539.053304 5632.373275 4406.459236 6505.164531 6164.276462 6840.007433 0.832223061 0.866145501 0.918889523 0.884030631 0.809802235 0.82344549 0.644218487 0.951046413 0.90120903 1 12.73978218 -13.5228787 0.176636312 1.698805175 0.792202439 0.192207134 0.082747637 40.7275572 0.462348934 9.801673475 0.108403724 3.00E-14 13.5228787 -0.906602736 SSS(ph)VGS(ph)SSS(ph)YPISPAVSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 3 0 S(0.172)S(0.199)S(0.878)VGS(0.749)S(0.139)S(0.308)S(0.359)Y(0.019)PIS(0.177)PAVSR 111.73 0.001694 23763000 1657.5 1428.4 1655.6 1684.6 1494.2 1989.6 1720.4 2012.8 1188 1514.6 TRUE FALSE FALSE 1526.307126 1551.864531 1716.957992 1677.629572 1476.382641 1576.934533 1768.669794 2626.493454 1057.679372 1567.232237 0.973887015 0.990194366 1.095535143 1.070440954 0.942031823 1.00619072 1.128530764 1.675880187 0.674870863 1 10.61400326 -4.238873964 2.454196292 0.998983707 1.852383091 0.781560615 0.111213761 0.086397462 0.603937266 0.006499847 0.157925019 5.77E-05 4.238873964 0.853399384 SSS(ph)VGS(ph)SSSYPISPAVSR ddPTM_HeLa_Curcumin_4h_R1 3 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 S(0.263)S(0.016)S(0.721)VGS(0.638)S(0.324)S(0.008)S(0.018)YPIS(0.007)PAVS(0.005)R;S(0.006)S(0.012)S(0.982)VGS(0.968)S(0.026)S(0.005)S(0.001)YPISPAVSR;S(0.027)S(0.032)S(0.947)VGS(0.626)S(0.254)S(0.061)S(0.047)Y(0.006)PISPAVSR ;; 166.67 3.69E-05 284290300 11217.2 9244.86 10147.97 11039.32 10128.7 11694.7 8880.02 5835.44 11751.5 10747.2 TRUE FALSE FALSE 10329.34678 10043.9445 10524.0627 10993.64222 10007.92187 9269.087394 9129.169462 7614.638793 10462.38985 11120.6644 0.928842595 0.903178456 0.946351973 0.988577824 0.899939204 0.833501224 0.820919428 0.684728764 0.940806185 1 13.44095536 -3.129174944 0.476018015 0.967400445 3.62E-15 0.868310527 0.032302687 3.081477434 0.211379088 0.007810326 2.135194687 0.00074272 3.129174944 -0.967400445 SSS(ph)VGSSSS(ph)YPISPAVSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 S(0.054)S(0.072)S(0.874)VGS(0.059)S(0.009)S(0.202)S(0.698)YPIS(0.029)PAVS(0.003)R 144.17 0.00052447 7306600 5420.9 4988.4 4603.3 4133 4670.7 5207.9 3699.8 3410.4 4962.7 3812.4 TRUE FALSE FALSE 4991.830045 5419.575068 4773.902347 4115.898741 4615.004953 4127.722835 3803.60643 4450.21526 4418.304226 3944.880616 1.265394452 1.373824862 1.210151285 1.043351914 1.169871893 1.04634924 0.964187969 1.128098843 1.120009616 1 11.94576593 -5.232555482 8.250616754 1.149923741 1.037686224 0.199547596 0.107642131 0.503459131 129.7492386 0.019373184 0.04890124 5.85E-06 5.232555482 -0.112237517 SSS(ph)VGSSSSYPIS(ph)PAVSR ddPTM_HeLa_Curcumin_4h_R1 2 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 2 0 S(0.206)S(0.314)S(0.481)VGSSSS(0.026)YPIS(0.974)PAVSR;S(0.19)S(0.015)S(0.702)VGS(0.09)S(0.002)S(0.001)S(0.005)YPIS(0.993)PAVS(0.001)R ; 228.08 3.66E-23 299931000 7866.9 6560.9 5838.7 5911.5 6114.5 8920.5 8180.7 6154.1 7972.1 5184.2 TRUE FALSE FALSE 7244.226564 7127.994961 6055.087358 5887.039779 6041.588581 7070.287745 8410.228425 8030.45676 7097.580575 5364.350564 1.350438693 1.328771279 1.12876429 1.097437557 1.126247904 1.318013739 1.567799927 1.497004468 1.323101555 1 12.38918781 -1.000015205 0.030784916 1.64E-08 3.161322088 0.193844635 0.155102596 980.0180421 2.336197855 76.14146923 187.0672319 0.099996499 1.000015205 3.161322072 SSS(ph)VGSSSSYPISPAVSR ddPTM_HeLa_Curcumin_4h_R1 6 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 S(0.108)S(0.003)S(0.889)VGSSSSYPISPAVSR;S(0.007)S(0.007)S(0.986)VGSSSSYPISPAVSR;S(0.001)SS(0.998)VGS(0.001)SSSYPISPAVSR;S(0.002)S(0.004)S(0.993)VGS(0.001)SSSYPISPAVSR;S(0.158)S(0.011)S(0.829)VGS(0.001)SSSYPISPAVSR;S(0.076)S(0.153)S(0.674)VGS(0.076)S(0.021)SSYPISPAVSR ;;;;; 336.79 3.64E-152 3944165000 18350.6 16657 16523.9 17437 16817.8 20458.7 17350.93 8855.41 21745.4 17798.2 TRUE FALSE FALSE 16898.13065 18096.75686 17136.29027 17364.85031 16617.25872 16215.335 17837.7504 11555.38374 19359.98402 18416.68613 0.917544586 0.982628293 0.930476317 0.942886804 0.902293638 0.880469749 0.968564609 0.627440988 1.051219741 1 14.16872587 -4.25938386 24.89209291 0.949608595 0.627440871 0.807024963 0.047719981 49.98072958 605213.5069 0.005939745 0.052065374 5.50E-05 4.25938386 -0.322167724 ALS(ph)SDSILS(ph)PAPDAR ddPTM_HeLa_Curcumin_4h_R1 2 ALSSDSILSPAPDAR 15 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 2 0 ALS(0.977)S(0.023)DS(0.29)ILS(0.71)PAPDAR;ALS(0.951)S(0.049)DSILS(1)PAPDAR ; 194.67 3.76E-06 37254000 4492.5 3691.67 4403.3 4073.6 3940.12 8330.4 7853.3 15547.2 5005.8 3775 TRUE FALSE FALSE 4136.913885 4010.761505 4566.490172 4056.744523 3893.136642 6602.581137 8073.642462 20287.46971 4456.676264 3906.180969 1.05906867 1.02677309 1.169042143 1.038544951 0.996660593 1.690290642 2.066888996 5.193684028 1.140929286 1 11.93154307 -3.404943456 1.061145035 1.034507136 23.14299612 0.986471597 0.143318605 0.60402667 0.139883644 0.019625551 23.33842545 0.000393601 3.404943456 22.10848898 up SSS(ph)VTSIDKESR ddPTM_HeLa_Curcumin_4h_R1 4 SSSVTSIDKESR 12 1 H0Y332;Q5T5C0-3;Q5T5C0-2;Q5T5C0;Q5JRH0 H0Y332 STXBP5 Syntaxin-binding protein 5 1 0 SS(0.022)S(0.966)VT(0.012)SIDKESR;SSS(0.844)VT(0.078)S(0.078)IDKESR;SS(0.003)S(0.957)VT(0.031)S(0.008)IDKESR;SS(0.069)S(0.738)VT(0.191)S(0.002)IDKESR ;;; 196.15 2.40E-05 33589700 11556.5 9196.3 8729 8705.3 8603.8 14073.6 11995.1 13591.9 11948.4 8936.1 TRUE FALSE FALSE 10641.79083 9991.187194 9052.504419 8669.279775 8501.205304 11154.57672 12331.65022 17736.00774 10637.69041 9246.62881 1.150883316 1.080522145 0.979005928 0.937561132 0.919384294 1.20633984 1.333637424 1.918105301 1.150439866 1 13.17471176 -4.195843001 1.475162034 1.04912203 2.35718097 0.909623522 0.083888901 0.309922212 0.538463269 0.013645285 0.618074633 6.37E-05 4.195843001 1.30805894 SSSALDS(ph)PAGPR ddPTM_HeLa_Curcumin_4h_R1 4 SSSALDSPAGPR 12 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 0 SSSALDS(1)PAGPR;SSSALDS(1)PAGPR;S(0.001)SS(0.006)ALDS(0.993)PAGPR;SSS(0.001)ALDS(0.999)PAGPR ;;; 172.33 0.00013519 259214000 11728 10038.6 9800.3 10676.8 11500.6 14414.3 9351.3 4498.14 11764.6 9761.4 TRUE FALSE FALSE 10799.71642 10906.29185 10163.50774 10632.62223 11363.46286 11424.6117 9613.67231 5869.602179 10474.05281 10100.60792 1.069214497 1.079765885 1.00622733 1.052671514 1.125027616 1.131081593 0.951791455 0.581113753 1.036972516 1 13.30215451 -4.291826127 3.219380134 1.048085526 0.529731605 0.914849454 0.043850792 0.070126936 1.166465826 0.007022298 0.086874645 5.11E-05 4.291826127 -0.518353921 SSSAS(ph)SPEMK ddPTM_HeLa_Curcumin_4h_R1 1 SSSASSPEMK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 SSSAS(0.5)S(0.5)PEMK 121.29 0.0043436 40575000 3935.4 4902.7 3921.7 3275 3688.4 3889.7 2434.6 1173 3187.8 2998.6 TRUE FALSE FALSE 3623.908937 5326.467542 4067.041652 3261.448918 3644.418239 3082.932374 2502.908324 1530.6423 2838.106315 3102.801127 1.167947538 1.716664177 1.310764527 1.051130506 1.174557469 0.993596511 0.806660892 0.493309831 0.914691661 1 11.59935552 -4.44978882 1.294030124 1.152534714 0.336810485 0.531579293 0.209087998 0.676122505 1.227843376 0.033037752 0.661112082 3.55E-05 4.44978882 -0.815724229 SSSASS(ph)PEMK ddPTM_HeLa_Curcumin_4h_R1 4 SSSASSPEMK 10 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 SSSAS(0.046)S(0.954)PEMK;SSSAS(0.205)S(0.795)PEMK;SSSAS(0.17)S(0.829)PEMK;SSSAS(0.004)S(0.996)PEMK ;;; 136.96 0.0022569 181950000 46887 54954 47557 37839.4 41892.1 43260.7 28009.7 12753.1 36147.4 36391.4 TRUE FALSE FALSE 43175.84448 59703.97889 49319.50426 37682.83059 41392.56407 34287.94317 28795.5768 16641.46148 32182.12066 37655.99844 1.146586102 1.585510446 1.309738323 1.00071256 1.099228962 0.910557271 0.764700924 0.44193388 0.85463464 1 15.20059208 -4.437619705 1.067412977 1.129066695 0.233454258 0.592083353 0.187814083 0.752178759 0.823700979 0.029187373 0.705727535 3.65E-05 4.437619705 -0.895612436 SSSCGS(ph)GGGGIS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SSSCGSGGGGISPK 14 0 F5H375;F5GWH4;Q96EP1-2;Q96EP1-4;Q96EP1 F5H375 CHFR E3 ubiquitin-protein ligase CHFR 2 0 SS(0.001)S(0.001)CGS(0.999)GGGGIS(0.999)PK 105.14 0.0088568 4933100 4415.8 3427.6 4029.2 4196.4 3629.9 3958.2 2490.1 1679.3 4199.9 3847.9 TRUE FALSE FALSE 4066.28477 3723.866471 4178.525696 4179.036409 3586.615813 3137.224702 2559.965504 2191.310839 3739.181478 3981.614239 1.021265378 0.93526551 1.049455182 1.04958345 0.900794401 0.787927839 0.642946642 0.550357395 0.939111941 1 11.95913774 -4.977008243 1.288288525 1.010137844 0.539978635 0.935058492 0.041994494 0.076408101 0.209717509 0.005353902 0.03338633 1.05E-05 4.977008243 -0.470159209 SSSET(ph)ILSSLAGSDIVK ddPTM_HeLa_Curcumin_4h_R1 1 SSSETILSSLAGSDIVK 17 0 Q01850 Q01850 CDR2 Cerebellar degeneration-related protein 2 1 0 S(0.014)S(0.047)S(0.156)ET(0.782)ILSSLAGSDIVK 161.48 0.00040071 56536000 2080.7 2216.1 2197.9 2159.1 2360.9 3874.7 2507.5 3495.3 3247.4 2423.4 TRUE FALSE FALSE 1916.010399 2407.649809 2279.356107 2150.166216 2332.747809 3071.043543 2577.853701 4561.00088 2891.168345 2507.61297 0.764077401 0.960136129 0.908974445 0.857455374 0.930266288 1.224688012 1.028010994 1.818861577 1.152956369 1 11.29209898 -1.171802923 0.830514838 0.894372857 199.9998277 0.772073104 0.134548391 117.3875954 0.465801179 0.018554022 43931.02154 0.067328211 1.171802923 199.1054548 SSSFS(ph)LPSR ddPTM_HeLa_Curcumin_4h_R1 2 SSSFSLPSR 9 0 Q14153-2;Q14153 Q14153-2 FAM53B Protein FAM53B 1 0 S(0.004)S(0.006)S(0.309)FS(0.681)LPSR;S(0.002)SS(0.007)FS(0.991)LPSR ; 120.45 0.0061181 46263000 5193.8 4282.5 4491.6 4539.9 4781.9 7009.8 4151.2 3490.1 5444.7 4624.8 TRUE FALSE FALSE 4782.70525 4652.660218 4658.062647 4521.115097 4724.878966 5555.888463 4267.6715 4554.215424 4847.430032 4785.511456 0.999413604 0.972238863 0.973367777 0.944750658 0.987329987 1.160981123 0.89179005 0.951667437 1.012938758 1 12.22445741 -7.211987649 0.002785601 1.983988576 6.65E-05 0.01700102 0.06554733 73201.59846 172.6876348 61430.24257 61553.86939 6.14E-08 7.211987649 -1.983922103 AGGPS(ph)DDDNADKPK ddPTM_HeLa_Curcumin_4h_R1 4 AGGPSDDDNADKPK 14 1 E7EVA0 E7EVA0 MAP4 Microtubule-associated protein 1 0 AGGPS(1)DDDNADKPK;AGGPS(1)DDDNADKPK;AGGPS(1)DDDNADKPK;AGGPS(1)DDDNADKPK ;;; 139 0.00034855 1159719000 23276 19105.6 21545 23568.2 23117.1 25146.1 18637.6 6062.56 26894.2 21947.8 TRUE FALSE FALSE 21433.68004 20757.00293 22343.47665 23470.68103 22841.44368 19930.51541 19160.5209 7911.006635 23943.97355 22710.48442 0.943779078 0.913983275 0.983839721 1.033473377 1.005766467 0.877590942 0.843686138 0.348341607 1.054313642 1 14.47107086 -4.139507911 1.686246525 0.973023614 2.54E-18 0.938516492 0.048333104 0.20568076 0.441405755 0.006276351 0.354254832 7.25E-05 4.139507911 -0.973023614 down SSSGESLAQSPDSS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SSSGESLAQSPDSSK 15 0 Q9H7U1-2;Q9H7U1;Q9H7U1-3 Q9H7U1-2 CCSER2 Serine-rich coiled-coil domain-containing protein 2 1 0 SSSGES(0.054)LAQS(0.041)PDS(0.355)S(0.55)K 128.82 0.00074456 25684000 4037.1 3254.5 3596.9 3868.4 3850.7 4525.1 3087.7 1741.8 4690.3 3291.8 TRUE FALSE FALSE 3717.559275 3535.804478 3730.204278 3852.393586 3804.782917 3586.543252 3174.332552 2272.866802 4175.785825 3406.189805 1.091412836 1.038052687 1.095125196 1.13099792 1.117020229 1.052948737 0.931930613 0.66727544 1.225940439 1 11.73394311 -4.312215169 2.108108785 1.059661879 0.584343453 0.793822304 0.065265802 0.165462474 0.877622052 0.007231771 0.142528547 4.87E-05 4.312215169 -0.475318426 SSSGLLEWESK ddPTM_HeLa_Curcumin_4h_R1 1 SSSGLLEWESK 11 0 P14866;M0QXS5;A0A3B3ITJ4;P14866-2;M0QYT0;M0R076 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 0 149.23 8.26E-06 3049000 2357.1 1958.1 2121 2587.4 2767.5 2332.9 2031.9 1648 2278.4 2028.3 FALSE FALSE TRUE 2170.533048 2127.349439 2199.606126 2576.694024 2734.49937 1849.030243 2088.909645 2150.467614 2028.46522 2098.783274 1.034186366 1.013610822 1.048038715 1.227708481 1.302897447 0.881001038 0.995295546 1.024625858 0.9664958 1 11.03533748 -6.518430599 23.64888993 1.017091333 1.087476302 0.104297228 0.111493145 202.5362662 1076801.773 0.018138863 0.026064764 3.03E-07 6.518430599 0.070384969 SSSIS(ph)EEKGDS(ph)DDEKPR ddPTM_HeLa_Curcumin_4h_R1 1 SSSISEEKGDSDDEKPR 17 2 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 2 0 S(0.005)S(0.006)S(0.1)IS(0.895)EEKGDS(0.994)DDEKPR 68.676 0.015509 28654000 3911.8 3488.9 2898.2 3692 3868 4241.1 3772 2192.9 4063.2 3854.3 TRUE FALSE FALSE 3602.176902 3790.46497 3005.609842 3676.723482 3821.876626 3361.448053 3877.832168 2861.505115 3617.477126 3988.236638 0.903200394 0.95041125 0.753618733 0.921892008 0.958287327 0.842840673 0.972317473 0.717486292 0.907036732 1 11.9615353 -13.52287875 0.131582904 1.429914164 0.827269184 0.103030396 0.084275586 76.48548979 0.711641008 8.539161923 0.262288391 3.00E-14 13.52287875 -0.602644979 SSSISEEKGDS(ph)DDEKPR ddPTM_HeLa_Curcumin_4h_R1 3 SSSISEEKGDSDDEKPR 17 2 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 SSSISEEKGDS(1)DDEKPR;SSSIS(0.001)EEKGDS(0.999)DDEKPR;SSS(0.001)IS(0.004)EEKGDS(0.996)DDEKPR ;; 105.92 0.0010431 1696057000 23467.6 19345.8 21426.8 21853.4 21694.8 21939.7 22451.4 21806.6 23462.7 20138.4 TRUE FALSE FALSE 21610.1147 21017.96475 22220.89606 21762.97642 21436.10368 17389.15891 23081.32586 28455.33195 20888.90051 20838.2079 1.037042859 1.00862631 1.066353506 1.044378505 1.028692284 0.834484376 1.107644475 1.365536427 1.002432676 1 14.34694359 -4.330486109 3.6526307 1.012658292 1.382114036 0.75491772 0.061976453 0.082495842 1.859710571 0.00818425 0.071759584 4.67E-05 4.330486109 0.369455745 SSSLEMTPYNT(ph)PQLSPATTPANKK ddPTM_HeLa_Curcumin_4h_R1 1 SSSLEMTPYNTPQLSPATTPANKK 24 1 Q14C86-4;Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;F8W9S7;Q14C86-3;H0Y4E7;H0Y7I9;C9IZ08;B4DGD8;B0QZ65;A0A0A0MQV8 Q14C86-4 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 1 0 S(0.041)S(0.041)S(0.034)LEMT(0.003)PY(0.173)NT(0.557)PQLS(0.15)PATTPANKK 108.37 1.61E-06 15889000 1536.7 1259.1 1414.2 1549.9 1517.1 1949.8 1011.7 1061.7 1672.8 1753.8 TRUE FALSE FALSE 1415.068573 1367.930994 1466.611496 1543.486924 1499.009573 1545.389501 1040.085579 1385.407443 1489.298025 1814.744419 0.779761909 0.753787133 0.808164213 0.850525786 0.826016908 0.851574186 0.573130612 0.763417387 0.820665439 1 10.82555066 -13.52287875 0.191979597 2.040261148 0.727684012 0.137403951 0.093645326 28.68008119 0.341015626 11.12963774 0.088640802 3.00E-14 13.52287875 -1.312577136 SSSLEMTPYNTPQLS(ph)PAT(ph)TPANKK ddPTM_HeLa_Curcumin_4h_R1 2 SSSLEMTPYNTPQLSPATTPANKK 24 1 Q14C86-4;Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;F8W9S7;Q14C86-3;H0Y4E7;H0Y7I9;C9IZ08;B4DGD8;B0QZ65;A0A0A0MQV8 Q14C86-4 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 2 0 S(0.003)S(0.003)S(0.003)LEMT(0.014)PY(0.096)NT(0.181)PQLS(0.595)PAT(0.552)T(0.552)PANKK;SSSLEMTPY(0.001)NT(0.013)PQLS(0.984)PAT(0.764)T(0.237)PANKK ; 80.994 0.00019353 0 2106.89 1727.09 1500.92 1915.72 1672.66 3086.7 2546.5 1112.59 2012.38 1709.4 TRUE FALSE FALSE 1940.127433 1876.371964 1556.545416 1907.793258 1652.714622 2446.483626 2617.947936 1451.813569 1791.626949 1768.801523 1.096859884 1.060815439 0.880000043 1.078579611 0.934369742 1.383130665 1.480068794 0.820789416 1.012904459 1 10.78855646 -5.266653699 24.99799777 1.03123399 1.253203543 0.243351774 0.172139553 408.9914506 1960752.456 0.022693356 0.052216278 5.41E-06 5.266653699 0.221969552 LYADS(ph)DS(ph)GDDSDKR ddPTM_HeLa_Curcumin_4h_R1 3 LYADSDSGDDSDKR 14 1 O43896 O43896 KIF1C Kinesin-like protein KIF1C 2 0 LY(0.003)ADS(0.999)DS(0.99)GDDS(0.008)DKR;LYADS(1)DS(0.887)GDDS(0.113)DKR;LYADS(1)DS(0.897)GDDS(0.103)DKR ;; 132.06 0.0015724 74902900 16915 14291.6 14533.2 15559.4 15592.4 16205.7 11475.2 4670.4 16092.7 14654.8 TRUE FALSE FALSE 15576.1599 15526.90222 15071.81318 15495.01933 15406.47081 12844.45514 11797.16323 6094.38346 14327.37107 15164.05321 1.027176553 1.023928234 0.993917191 1.021825703 1.015986333 0.84703311 0.777968995 0.401896734 0.944824637 1 13.8883678 -4.139388377 1.050744107 1.0144341 3.05E-21 0.961519432 0.036497294 0.210016655 0.153753842 0.004175449 0.251954031 7.25E-05 4.139388377 -1.0144341 down SSSLGNS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 2 SSSLGNSPER 10 0 Q5SQI0-7;Q5SQI0-6;Q5SQI0-5;Q5SQI0-4;Q5SQI0-3;Q5SQI0-2;Q5SQI0 Q5SQI0-7 ATAT1 Alpha-tubulin N-acetyltransferase 1 1 0 SSSLGNS(0.999)PER;SSSLGNS(1)PER ; 116.84 0.0051144 20011200 3481.7 3174.8 3327.3 3090.7 4211.7 4723.7 3734.8 3457.5 3403 2884.3 TRUE FALSE FALSE 3206.119771 3449.215565 3450.612665 3077.911502 4161.478228 3743.951373 3839.588436 4511.675834 3029.699414 2984.52921 1.074246404 1.155698377 1.156166491 1.031288785 1.394349974 1.254452917 1.286497188 1.511687612 1.015134784 1 11.54328766 -1.00000001 0.215660854 0.987153263 3.514065816 0.762569356 0.079508893 15.85572201 0.188147879 0.058272427 13.98410982 0.099999998 1.00000001 2.526912554 S(ph)RTLTAVHDAILEDLVFPSEIVGK ddPTM_HeLa_Curcumin_4h_R1 1 SRTLTAVHDAILEDLVFPSEIVGK 24 1 P62081;A0A2R8Y623;B5MCP9 P62081 RPS7 40S ribosomal protein S7 1 0 S(0.331)RT(0.331)LT(0.331)AVHDAILEDLVFPS(0.008)EIVGK 42.416 0.019601 4313300 1581.4 1135.8 1395.2 1264 1433 2119 1778.8 2346.8 1634.8 1287.9 TRUE FALSE FALSE 1456.230521 1233.973491 1446.907339 1258.769903 1415.912411 1679.495514 1828.708341 3062.328517 1455.46653 1332.654429 1.092729285 0.925951593 1.085733336 0.944558376 1.062475297 1.260263334 1.372229965 2.297916436 1.092156 1 10.38008701 -3.337286178 0.995900098 1.031357989 8.121203884 0.967123537 0.069574875 1.130970832 0.219544417 0.010321531 13.3246521 0.000459953 3.337286178 7.089845895 up SSSMSS(ph)LTGAYTSGIPSSSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSMSSLTGAYTSGIPSSSR 20 0 A8CG34-2;A8CG34 A8CG34-2 POM121C Nuclear envelope pore membrane protein POM 121C 1 0 S(0.005)S(0.005)S(0.281)MS(0.281)S(0.427)LT(0.001)GAYTSGIPSSSR 76.588 0.0043522 5934100 1692.2 1257.8 1338.1 1512.6 1579.7 1465.6 834.38 689.58 2060.6 1558.4 TRUE FALSE FALSE 1558.260584 1366.518627 1387.691163 1506.341262 1560.863109 1161.618039 857.7904572 899.8297676 1834.557335 1612.554284 0.966330622 0.847424884 0.860554697 0.934133677 0.967944537 0.72035903 0.531945167 0.558015179 1.137671676 1 10.65513201 -5.052856568 2.47859663 0.959828519 0.541579639 0.829128276 0.076562831 0.067933647 0.812397458 0.009044843 0.030888273 8.85E-06 5.052856568 -0.418248879 SSSNDS(ph)VDEETAESDTSPVLEK ddPTM_HeLa_Curcumin_4h_R1 2 SSSNDSVDEETAESDTSPVLEK 22 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 0 S(0.053)S(0.053)S(0.068)NDS(0.82)VDEET(0.005)AESDTSPVLEK;S(0.024)S(0.024)S(0.096)NDS(0.855)VDEET(0.001)AESDTSPVLEK ; 157.64 5.02E-07 36822000 8297 6750.2 7414.3 7339.6 7826.5 7913.4 6464.4 5139.7 7449 6235.6 TRUE FALSE FALSE 7640.283695 7333.65721 7689.08048 7309.23068 7733.174099 6272.071638 6645.773666 6706.77087 6631.863336 6452.286636 1.184120317 1.136598174 1.191683029 1.132812457 1.198516826 0.972069592 1.029987358 1.039440937 1.027831482 1 12.65559481 -5.243812458 24.95850571 1.110655595 1.015448103 0.363809991 0.065283455 993.6353681 1406917.569 0.011834737 0.030086509 5.70E-06 5.243812458 -0.095207492 SSSPAGET(ph)EGDREPQARPGEGTAPLPPPGQK ddPTM_HeLa_Curcumin_4h_R1 2 SSSPAGETEGDREPQARPGEGTAPLPPPGQK 31 2 Q9BTC0 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 0 S(0.094)S(0.094)S(0.323)PAGET(0.471)EGDREPQARPGEGT(0.017)APLPPPGQK;S(0.012)S(0.012)S(0.034)PAGET(0.933)EGDREPQARPGEGT(0.01)APLPPPGQK ; 69.99 0.00021747 103335000 3238.8 2360 2606.2 2766.1 2414 2960.9 2779.7 1738.28 3206.2 2684.4 TRUE FALSE FALSE 2982.445562 2563.987884 2702.788065 2754.654611 2385.214627 2346.775964 2857.690901 2268.27357 2854.487882 2777.6827 1.073717154 0.923067233 0.973037008 0.991709604 0.858706657 0.844868265 1.028803938 0.816606436 1.027650812 1 11.43966609 -6.518891539 1.013279704 1.032303219 0.899522758 0.384737191 0.065662479 0.360770329 0.739446592 0.012334695 0.022149688 3.03E-07 6.518891539 -0.132780461 SSSPAPADIAQTVQEDLR ddPTM_HeLa_Curcumin_4h_R1 2 SSSPAPADIAQTVQEDLR 18 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 0 0 ; ; 252.12 6.48E-41 16939200 3315 2482.8 2462.7 2856 2622.5 2991.2 2199.34 1579.59 2925.8 2569.8 FALSE FALSE TRUE 3052.614252 2697.402169 2553.969828 2844.182629 2591.2284 2370.791402 2261.047561 2061.199719 2604.84706 2659.100359 1.147987605 1.014404048 0.960463873 1.069603341 0.974475594 0.891576504 0.850305463 0.775149277 0.979597123 1 11.37672251 -4.924530465 0.742178518 1.064116908 0.724891306 0.703327522 0.055274942 0.562226936 0.366194877 0.011224481 0.131337658 1.19E-05 4.924530465 -0.339225602 SSSPAPEFLAS(ph)SPPDNK ddPTM_HeLa_Curcumin_4h_R1 1 SSSPAPEFLASSPPDNK 17 0 C9JME2;Q9Y4F1;Q9Y4F1-2;M0QXT1 C9JME2 FARP1 "FERM, RhoGEF and pleckstrin domain-containing protein 1" 1 0 S(0.002)S(0.001)S(0.003)PAPEFLAS(0.497)S(0.497)PPDNK 112.17 0.0020391 0 917.16 1200.4 1055.3 1096.4 1175 1536.5 1067.6 630.43 1413.9 804.72 TRUE FALSE FALSE 844.5658182 1304.157227 1094.410346 1091.863387 1160.988892 1217.81258 1097.553983 822.6452049 1258.798707 832.6839601 1.014269349 1.566209138 1.314316594 1.31125786 1.394273155 1.462514758 1.3180919 0.987944099 1.511736466 1 9.701625224 -7.314954424 13.99838919 1.006714288 1.340925429 0 0.212188003 1.513417104 395.5045707 0.022998265 0.026296036 4.84E-08 7.314954424 0.334211141 SSSPAT(ph)EQSWMENDFDELREEGFRR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPATEQSWMENDFDELREEGFRR 25 2 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 0 S(0.024)S(0.103)S(0.388)PAT(0.471)EQS(0.014)WMENDFDELREEGFRR 69.256 0.00024941 6419100 1878.1 1730.4 1775.2 1769.4 1949.4 2360.8 1436.3 1793.5 2131.1 2168.8 TRUE FALSE FALSE 1729.446403 1879.968065 1840.990474 1762.078692 1926.154678 1871.143468 1476.598712 2340.329894 1897.323662 2244.165639 0.770641157 0.837713595 0.820345184 0.785182101 0.858294346 0.833781356 0.657972249 1.042850783 0.845447247 1 11.13196345 -9.365889014 0.997696285 1.004111113 0.816899149 0.04246968 0.101795833 0.452549488 0.777564987 0.062253097 0.014778451 4.31E-10 9.365889014 -0.187211964 SSSPATEQS(ph)WMENDFDELREEGFR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPATEQSWMENDFDELREEGFR 24 1 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 0 S(0.001)S(0.001)S(0.04)PAT(0.027)EQS(0.931)WMENDFDELREEGFR 190.1 2.23E-14 15006000 359.28 452.71 561.65 482.55 360.42 525.88 448.18 390.57 534.12 324.26 TRUE FALSE FALSE 330.8426089 491.8402352 582.4652431 480.553336 356.1222269 416.8065601 460.7547246 509.652995 475.5283723 335.5280109 0.986035735 1.465869374 1.735966072 1.432230158 1.06137853 1.242240727 1.37322283 1.518958115 1.417253871 1 8.390289402 -7.266843744 24.45073149 0.993405751 1.397485993 0.170328911 0.212746505 188.5950388 853250.7093 0.030312221 0.035208672 5.41E-08 7.266843744 0.404080241 SSSPVT(ph)ELASRS(ph)PIRQDR ddPTM_HeLa_Curcumin_4h_R1 1 SSSPVTELASRSPIRQDR 18 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 S(0.001)S(0.001)S(0.03)PVT(0.964)ELAS(0.336)RS(0.669)PIRQDR 102.89 0.0042266 16587000 5387.9 4241 4262.4 5344.9 4521.7 6783.2 5673.3 5150.4 6147.3 5556.5 TRUE FALSE FALSE 4961.44203 4607.573142 4420.368294 5322.78422 4467.781681 5376.287858 5832.477529 6720.73325 5472.95657 5749.587961 0.862921319 0.801374494 0.768814796 0.925767943 0.777061193 0.93507359 1.01441661 1.168906937 0.951886745 1 12.48924286 -4.430850786 2.042700793 0.900101839 1.196251809 0.586392665 0.075866992 0.355117475 2.067407463 0.013125249 0.170133025 3.71E-05 4.430850786 0.296149971 SSSQLGS(ph)PDVSHLIR ddPTM_HeLa_Curcumin_4h_R1 2 SSSQLGSPDVSHLIR 15 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 0 SSSQLGS(1)PDVSHLIR;SSSQLGS(1)PDVSHLIR ; 156.15 0.00017329 16035800 3337 3320.9 2795.2 3221.6 3240 4834.5 3464.6 1157.86 4042.3 3086.1 TRUE FALSE FALSE 3072.872929 3607.943798 2898.792571 3208.269873 3201.365116 3831.770204 3561.807352 1510.886184 3598.869803 3193.341745 0.962275 1.129833286 0.907761462 1.004674767 1.002512531 1.199924878 1.115385585 0.47313639 1.12699175 1 11.64085124 -4.254544773 24.83199155 1.010765575 0.473136117 0.765294989 0.093591959 266.8194221 960964.0742 0.012308677 0.162634758 5.56E-05 4.254544773 -0.537629458 SSSQPAAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 SSSQPAAKR 9 1 O94776;O94776-2 O94776 MTA2 Metastasis-associated protein MTA2 0 1 SSSQPAAK(1)R 113.62 0.00082212 637670 246.48 285.5 294.06 203.59 300.66 262.98 230.97 163.1 177.99 130.47 FALSE TRUE FALSE 226.9708479 310.1773478 304.9581223 202.7475985 297.0748259 208.4349836 237.4503966 212.8284392 158.4649423 135.0038228 1.681217933 2.297544925 2.258885089 1.501791537 2.200491954 1.543919122 1.758842021 1.576462316 1.17378115 1 7.076856449 -8.581561972 0.873567607 1.059136929 1.86239529 0.521955847 0.290845958 0.299427373 0.465418741 0.124586747 0.062105213 2.62E-09 8.581561972 0.803258362 SSSQTSGSLVS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SSSQTSGSLVSK 12 0 Q9NXV6 Q9NXV6 CDKN2AIP CDKN2A-interacting protein 1 0 SSSQT(0.071)S(0.151)GS(0.083)LVS(0.695)K 139.48 0.0012507 8830100 1308.1 1256.5 1140.5 1296.9 1268.9 2187.6 1586.5 831.36 1125.1 978.43 TRUE FALSE FALSE 1204.562505 1365.106261 1182.767933 1291.533771 1253.769196 1733.867101 1631.01292 1084.837837 1001.679345 1012.43037 1.189773184 1.348345824 1.168246201 1.275676639 1.238375728 1.712579109 1.610987747 1.071518466 0.989380974 1 9.983606974 -7.223222846 0.335764336 0.983469691 1.476647715 0.399289883 0.177798125 0.938717084 0.318352624 0.142291264 0.1694165 5.98E-08 7.223222846 0.493178024 SSSS(ph)FTPFIDPR ddPTM_HeLa_Curcumin_4h_R1 1 SSSSFTPFIDPR 12 0 O95819-3;E7EX83;G5E948;C9J840;H7C360;E7ENQ1;H7C0P6;G3XAA2;A0A0D9SG62;A0A0D9SEY1;O95819-4;O95819-2;O95819;O95819-5;O95819-6;E7EN19 O95819-3 MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 1 0 SSS(0.035)S(0.733)FT(0.231)PFIDPR 204.69 5.90E-09 5281400 735.94 594.21 527.25 754.92 699.21 845.06 693.75 379 731.05 775.71 TRUE FALSE FALSE 677.6895724 645.5708647 546.7903488 751.7963411 690.8723774 669.7850302 713.2147579 494.5553553 650.855644 802.6658648 0.844298484 0.804283442 0.681217893 0.936624284 0.86072226 0.834450622 0.88855748 0.616141008 0.810867476 1 9.648655735 -8.800667482 0.615593243 1.008055211 0.809501635 2.82E-06 0.106636079 0.674567948 0.471155947 0.068551355 0.021072818 1.58E-09 8.800667482 -0.198553577 SSSS(ph)PELQTLQDILGDPGDKADVGR ddPTM_HeLa_Curcumin_4h_R1 2 SSSSPELQTLQDILGDPGDKADVGR 25 1 H3BMQ0;A0A2R8YDR3;A0A2R8Y7X5;P49815-3;P49815-5;A0A2R8Y6C9;A0A2R8Y5F1;P49815;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDZ2;A0A2R8YGU4;X5D2U8;P49815-2;P49815-6;P49815-7;P49815-4;H3BQK4;A0A2R8Y670 H3BMQ0 TSC2 Tuberin 1 0 S(0.055)S(0.055)S(0.267)S(0.623)PELQTLQDILGDPGDKADVGR;S(0.014)S(0.014)S(0.262)S(0.689)PELQT(0.021)LQDILGDPGDKADVGR ; 128.49 2.53E-08 21198000 4402 4430.9 4406.7 4876.4 5101.9 6261.7 4905.2 3195.1 4812.7 3978.8 TRUE FALSE FALSE 4053.577055 4813.887252 4570.016179 4856.222749 5041.063175 4962.952836 5042.82671 4169.271282 4284.758851 4117.063004 0.984579797 1.169252753 1.110018519 1.179535689 1.224431875 1.205459531 1.224860223 1.012680952 1.040731912 1 12.00739981 -7.260402857 24.90107202 0.992718235 1.166270176 0.559302862 0.061412314 37.81695634 908505.7565 0.009592308 0.011396049 5.49E-08 7.260402857 0.173551941 AS(ph)WES(ph)LDEEWRAPQAGSR ddPTM_HeLa_Curcumin_4h_R1 1 ASWESLDEEWRAPQAGSR 18 1 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 2 0 AS(1)WES(1)LDEEWRAPQAGSR 65.416 0.013863 15331000 2703.7 2213.4 2657.3 2753.6 2697.8 3145.4 2186.1 935.15 3109.9 2628.2 TRUE FALSE FALSE 2489.699292 2404.716433 2755.781876 2742.206333 2665.630497 2493.008584 2247.436082 1220.27293 2768.751751 2719.529754 0.915488896 0.884239795 1.01333029 1.008338419 0.98018067 0.916705758 0.826406138 0.448707328 1.018099451 1 11.4091415 -4.138460666 1.633526539 0.961895715 0.141755984 0.928874281 0.04339766 0.274644734 0.545925441 0.006791029 0.388748027 7.27E-05 4.138460666 -0.820139731 down SSSSGS(ph)DDYAYTQALLLHQR ddPTM_HeLa_Curcumin_4h_R1 1 SSSSGSDDYAYTQALLLHQR 20 0 F6SS63;Q8N5C8-2;Q8N5C8 F6SS63 TAB3 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 1 0 S(0.009)S(0.009)S(0.367)S(0.081)GS(0.53)DDY(0.002)AY(0.001)TQALLLHQR 127.2 6.99E-05 11637000 2495.9 2337.4 2644.4 2621.4 2181.9 970.78 1264.9 2169.5 2391.9 2164.4 TRUE FALSE FALSE 2298.346881 2539.434441 2742.40379 2610.553341 2155.882268 769.4292851 1300.38969 2830.970563 2129.514554 2239.612739 1.026225133 1.133872118 1.224499103 1.165627118 0.962613862 0.343554612 0.580631494 1.264044678 0.950840526 1 11.12903358 -5.503712863 24.40126665 1.050613206 0.704290982 0.317001731 0.228528819 486.6403453 619570.8266 0.031353812 0.069040832 3.14E-06 5.503712863 -0.346322224 SSSSS(ph)ASPS(ph)SPSSREEK ddPTM_HeLa_Curcumin_4h_R1 1 SSSSSASPSSPSSREEK 17 1 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 0 S(0.02)S(0.027)S(0.068)S(0.095)S(0.626)AS(0.22)PS(0.847)S(0.092)PS(0.005)S(0.001)REEK 125.41 0.0016706 13216000 3729.8 3162.9 2897.3 3315.3 2878.1 4122.4 2856 2147.5 4215.7 3089.3 TRUE FALSE FALSE 3434.582394 3436.286982 3004.676487 3301.582167 2843.780537 3267.367771 2936.131673 2802.262864 3753.248257 3196.652945 1.074430804 1.074964046 0.939944541 1.032824715 0.889611912 1.022121521 0.918501859 0.876624054 1.174118155 1 11.64234641 -5.178688285 0.599035123 1.036240375 0.873680028 0.437964953 0.067346315 1.070800652 0.47894388 0.010627726 0.098194914 6.63E-06 5.178688285 -0.162560347 SSSSS(ph)QESLNRPFSSK ddPTM_HeLa_Curcumin_4h_R1 2 SSSSSQESLNRPFSSK 16 1 E3W994;J3KR49;O75122;E7ERI8;E7EW49;O75122-3;A0A0U1RQI6;B3KR06;E7ENG2;O75122-2 E3W994 CLASP2 CLIP-associating protein 2 1 0 SSSS(0.014)S(0.986)QESLNRPFSSK;SSS(0.002)S(0.128)S(0.856)QES(0.013)LNRPFS(0.001)SK ; 308 2.66E-94 41589000 6780.3 5499.2 6244.4 5362.2 5414.5 6282.9 4286.5 4249 6841.3 4820.7 TRUE FALSE FALSE 6243.6321 5974.526344 6475.822957 5340.012637 5349.935624 4979.755717 4406.767653 5544.50054 6090.826506 4988.218966 1.251675627 1.197727362 1.298223474 1.070524905 1.07251419 0.998303353 0.883435086 1.111519077 1.221042329 1 12.28430908 -5.58886173 2.115775688 1.141064251 0.988182023 0.375253757 0.098213725 0.363299312 3.261759641 0.018295455 0.044103832 2.58E-06 5.58886173 -0.152882228 SSSSS(ph)QESLNRPLSAK ddPTM_HeLa_Curcumin_4h_R1 1 SSSSSQESLNRPLSAK 16 1 Q7Z460;Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460;Q7Z460-4 CLASP1 CLIP-associating protein 1 1 0 S(0.001)S(0.001)S(0.006)S(0.102)S(0.89)QESLNRPLSAK 121.02 0.0083664 8245100 3034.6 2318.8 2288.4 2508.2 2969.6 3371.8 2879.4 2339.1 3454.6 2885.9 TRUE FALSE FALSE 2794.408208 2519.22674 2373.210117 2497.821733 2934.18946 2672.450672 2960.188214 3052.280822 3075.639023 2986.18481 0.935778723 0.843627203 0.79472982 0.836459192 0.982588033 0.894938137 0.991294378 1.022133932 1.02995602 1 11.54408774 -3.191134182 13.52674976 0.941952301 0.919693415 0 0.081454718 0 0 0.011358727 0 0.00064397 3.191134182 -0.022258886 SSSSSAS(ph)PS(ph)SPSSREEK ddPTM_HeLa_Curcumin_4h_R1 1 SSSSSASPSSPSSREEK 17 1 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 0 S(0.019)S(0.025)S(0.043)S(0.077)S(0.186)AS(0.655)PS(0.961)S(0.033)PSSREEK 106.19 0.0056965 13397000 2645.5 2046 2037.8 1952 1613.9 2435.6 1681.4 1547.9 2493.2 2009.6 TRUE FALSE FALSE 2436.105883 2222.847123 2113.322661 1943.923141 1594.655297 1930.429105 1728.575559 2019.847584 2219.702198 2079.43345 1.171523851 1.068967667 1.016297329 0.934833063 0.76687008 0.928343778 0.831272363 0.971345144 1.067455271 1 11.0219748 -6.318844269 2.299967444 1.081626068 0.87415071 0.663820326 0.065110488 0.159099829 1.64623173 0.012586635 0.021058233 4.80E-07 6.318844269 -0.207475358 SSSSSASPS(ph)SPSSREEK ddPTM_HeLa_Curcumin_4h_R1 1 SSSSSASPSSPSSREEK 17 1 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 S(0.001)S(0.001)S(0.004)S(0.025)S(0.001)AS(0.025)PS(0.468)S(0.468)PS(0.003)S(0.005)REEK 113.01 0.0094013 1657200 1217.2 602.88 680.31 928.87 715.23 984.31 765.46 593.08 999.19 931.47 TRUE FALSE FALSE 1120.857336 654.9902608 705.5228871 925.0265821 706.7013494 780.1530105 786.9367475 773.9073618 889.5813569 963.8385132 1.162909886 0.679564317 0.731992836 0.959731915 0.733215512 0.809422948 0.816461198 0.802942974 0.922956849 1 9.912647639 -7.264981383 24.99998983 1.07692967 0.794262288 0.565775474 0.092712697 126.4416912 892442.809 0.015200195 0.017744919 5.43E-08 7.264981383 -0.282667383 SSSSSASPSS(ph)PSSR ddPTM_HeLa_Curcumin_4h_R1 5 SSSSSASPSSPSSR 14 0 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 SSSSSAS(0.014)PS(0.084)S(0.872)PS(0.029)S(0.001)R;SSSSSASPSS(0.706)PS(0.288)S(0.006)R;SSSSSAS(0.001)PS(0.051)S(0.893)PS(0.048)S(0.007)R;SSSSSASPS(0.002)S(0.965)PS(0.03)S(0.003)R;SSSSS(0.001)AS(0.02)PS(0.032)S(0.901)PS(0.044)S(0.001)R ;;;; 209.11 2.13E-09 922089740 21017.5 21621.5 20500.94 17540.58 22485.35 22056.33 15532.76 14349.83 17383.41 18464.58 TRUE FALSE FALSE 19353.9427 23490.36612 21260.72287 17468.00173 22217.22689 17481.59853 15968.56744 18725.02711 15476.49341 19106.22278 1.012965405 1.229461542 1.112764313 0.914257199 1.162826747 0.914968842 0.835778355 0.980048612 0.810023708 1 14.22175497 -5.036807536 24.27154571 1.033807152 0.899778481 0.190380336 0.117323809 365.7036597 241151.6147 0.013244318 0.033780817 9.19E-06 5.036807536 -0.134028671 SSSSSASPSS(ph)PSSREEK ddPTM_HeLa_Curcumin_4h_R1 3 SSSSSASPSSPSSREEK 17 1 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 SSSSSAS(0.303)PS(0.148)S(0.491)PS(0.045)S(0.014)REEK;SSSS(0.003)S(0.016)AS(0.18)PS(0.185)S(0.612)PS(0.003)S(0.001)REEK;SSSSSASPS(0.199)S(0.788)PS(0.004)S(0.008)REEK ;; 162.26 0.0012723 4122330 4817.05 4505.79 4154.67 4328.76 3270.85 5816.15 4067.97 3613.55 6106.88 4774.02 TRUE FALSE FALSE 4435.77541 4895.25041 4308.645725 4310.848738 3231.84725 4609.814928 4182.10629 4715.30476 5436.970543 4939.91684 0.897945361 0.99095806 0.872210174 0.872656135 0.654231104 0.933176626 0.846594472 0.954531202 1.100619852 1 12.27027104 -6.620120531 4.916932604 0.953278056 0.847737306 0.322658891 0.09233237 0.214952992 8.726475918 0.012967441 0.018479626 2.40E-07 6.620120531 -0.10554075 SSSSSASPSSPSS(ph)REEKESK ddPTM_HeLa_Curcumin_4h_R1 1 SSSSSASPSSPSSREEKESK 20 2 E9PK91;Q9NYF8-3;H0YF63;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 SSSSSAS(0.007)PS(0.085)S(0.206)PS(0.206)S(0.495)REEKES(0.001)K 79.565 0.0020177 20873000 2640.6 1975.9 1588.7 2591.1 1321 3312.7 1930.8 1907.6 4200.7 2983.9 TRUE FALSE FALSE 2431.593724 2146.687992 1647.57862 2580.378715 1305.247938 2625.608678 1984.973052 2489.218458 3739.89372 3087.590303 0.787537686 0.695263225 0.533613096 0.835725748 0.422740004 0.8503747 0.642887448 0.806201022 1.211266183 1 11.59226562 -8.269929195 0.714692823 0.981848622 0.678468039 0.517408226 0.148587381 0.369195052 0.407824552 0.050697647 0.028764069 5.37E-09 8.269929195 -0.303380583 GLPNGPTHAFSS(ph)PSES(ph)PDSTVDR ddPTM_HeLa_Curcumin_4h_R1 1 GLPNGPTHAFSSPSESPDSTVDR 23 0 Q9ULJ7-2;Q9ULJ7 Q9ULJ7-2 ANKRD50 Ankyrin repeat domain-containing protein 50 2 0 GLPNGPT(0.014)HAFS(0.57)S(0.614)PS(0.213)ES(0.55)PDS(0.02)T(0.018)VDR 65.744 0.0056009 5245800 1500.8 1060.4 1285.2 1328.9 1343.4 1638.5 1047.9 410.64 1626 1373 TRUE FALSE FALSE 1382.010096 1152.056251 1332.830643 1323.401364 1327.380832 1298.65663 1077.301254 535.8422456 1447.631868 1420.711648 0.972759038 0.810900828 0.938142968 0.931505958 0.934306996 0.914088818 0.758282833 0.377164674 1.018948405 1 10.47239805 -4.136964758 1.352997786 0.963285716 1.29E-16 0.907412633 0.05467072 0.364974717 0.468777992 0.008644114 0.518480531 7.30E-05 4.136964758 -0.963285716 down SQSES(ph)SDEVTELDLSHGK ddPTM_HeLa_Curcumin_4h_R1 2 SQSESSDEVTELDLSHGK 18 0 Q86YS7;Q86YS7-5;Q86YS7-3;Q86YS7-2;Q86YS7-4 Q86YS7;Q86YS7-3 C2CD5 C2 domain-containing protein 5 1 0 S(0.331)QS(0.203)ES(0.386)S(0.08)DEVTELDLSHGK;S(0.115)QS(0.064)ES(0.703)S(0.118)DEVTELDLSHGK ; 147.02 7.78E-05 17724700 4171.1 4034.8 4337.2 4212.3 4407.1 3845 3242.2 1226.13 4649.5 4122.6 TRUE FALSE FALSE 3840.953034 4383.550133 4497.940447 4194.870619 4354.548211 3047.503658 3333.167406 1599.971393 4139.461482 4265.860043 0.900393589 1.027588831 1.05440413 0.983358708 1.02079022 0.714393728 0.781358829 0.375064202 0.970369736 1 12.05862092 -4.136676529 0.999547637 0.970434626 6.82E-15 0.862424105 0.073971247 0.654601219 0.427806055 0.011854916 0.719743041 7.30E-05 4.136676529 -0.970434626 down SSSSTTTGEK(ac)ITK ddPTM_HeLa_Curcumin_4h_R1 2 SSSSTTTGEKITK 13 1 A0A3F2YNW7;Q8NFD5;Q8NFD5-2;Q8NFD5-3;H0Y7H8;H0Y3S9;H0Y2R3;A0A1B0GV63;A0A1B0GWJ2;A0A1B0GTJ8;A0A1B0GVK1;Q8NFD5-4 A0A3F2YNW7 ARID1B AT-rich interactive domain-containing protein 1B 0 1 ; SSSSTTTGEK(1)ITK;SSSSTTTGEK(1)ITK 203.61 1.32E-19 3248000 1308.83 1291.53 1422.3 1152.62 1251.88 1648.29 1118.74 1003.01 1476.76 1046.65 FALSE TRUE FALSE 1205.234724 1403.164098 1475.011689 1147.850764 1236.952149 1306.416074 1150.128833 1308.823132 1314.763123 1083.02101 1.112845193 1.295601919 1.361941898 1.059860108 1.142131258 1.206270296 1.061963548 1.208492836 1.213977486 1 10.08084551 -8.051690814 1.316972268 1.026938749 1.183321564 0 0.108104685 0.315159493 1.130042715 0.023317003 0.019270518 8.88E-09 8.051690814 0.156382815 SSSSVGS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 1 SSSSVGSPTR 10 0 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 0 SSSSVGS(0.999)PT(0.001)R 158.06 0.00062588 110050000 3752.7 4200.2 3414.8 2955.5 2859.5 3324.8 2010.2 1043.4 2985.5 3249 TRUE FALSE FALSE 3455.669835 4563.246572 3541.355492 2943.270924 2825.40233 2635.199002 2066.600802 1361.527857 2657.998119 3361.902508 1.02789115 1.357340542 1.053378402 0.875477774 0.840417687 0.783841588 0.614711699 0.404987311 0.7906232 1 11.71506217 -4.724787602 0.78129172 1.041854426 0.270846949 0.689338044 0.137520295 0.553530871 0.356594947 0.020207853 0.321690898 1.88E-05 4.724787602 -0.771007478 SSSSVSSQGSVASSTGS(ph)PASIR ddPTM_HeLa_Curcumin_4h_R1 1 SSSSVSSQGSVASSTGSPASIR 22 0 A0A087WXK8;Q9H4H8-2;Q9H4H8 A0A087WXK8 FAM83D Protein FAM83D 1 0 SSSSVSSQGSVASSTGS(1)PASIR 297.3 2.60E-88 5576000 2038.2 1527.3 1482.2 1789.4 1594.1 2414.2 1457.2 675.68 1975.6 1609.2 TRUE FALSE FALSE 1876.874319 1659.313006 1537.131636 1781.995937 1575.091399 1913.467706 1498.08511 881.6917216 1758.881623 1665.11958 1.12717089 0.996512819 0.923135884 1.070190969 0.945932903 1.149147322 0.899686201 0.529506548 1.056309495 1 10.70141007 -4.324722234 2.924258774 1.044219683 0.476984127 0.822693582 0.070162251 0.10352169 1.337778422 0.010501887 0.126901877 4.73E-05 4.324722234 -0.567235556 SSST(ph)GNLLDKDDLAIPPPDYGAASR ddPTM_HeLa_Curcumin_4h_R1 1 SSSTGNLLDKDDLAIPPPDYGAASR 25 1 B4DWA1;I3L4C2;Q9UQB8-3;Q9UQB8-5;Q9UQB8-4;Q9UQB8-2;Q9UQB8;I3L3C6;Q9UQB8-6 B4DWA1 BAIAP2 Brain-specific angiogenesis inhibitor 1-associated protein 2 1 0 S(0.054)S(0.054)S(0.191)T(0.7)GNLLDKDDLAIPPPDYGAASR 73.919 0.00039994 128690000 3644 4060 3212.2 3339.7 2958.7 4247.1 2544.8 3361.8 4816.2 3578.6 TRUE FALSE FALSE 3355.573555 4410.928309 3331.246958 3325.881206 2923.419435 3366.203585 2616.200239 4386.797344 4287.87491 3702.956084 0.906187781 1.191191094 0.899618273 0.898169228 0.78948261 0.909058468 0.70651668 1.184674418 1.157959968 1 11.85446172 -6.549629224 24.99990891 0.975613382 0.883327307 0.1352441 0.147275229 382.0673385 357063.1338 0.020010368 0.028299334 2.82E-07 6.549629224 -0.092286075 SSSTS(ph)ESGDSDNMR ddPTM_HeLa_Curcumin_4h_R1 1 SSSTSESGDSDNMR 14 0 H0YM23;O75179-6;O75179-7;O75179-2;O75179;O75179-4 H0YM23 ANKRD17 Ankyrin repeat domain-containing protein 17 1 0 SSS(0.001)T(0.002)S(0.99)ES(0.007)GDSDNMR 145.61 3.34E-05 0 1143.1 1237 1208.6 1285.7 932.5 1254.3 941.07 1047.7 1355.3 1315.2 TRUE FALSE FALSE 1052.622429 1343.920768 1253.391779 1280.380114 921.3805465 994.1440411 967.4738914 1367.138907 1206.626981 1360.903102 0.773473458 0.987521276 0.921000016 0.940831211 0.677036113 0.730503178 0.710905787 1.004582108 0.886636954 1 10.41034863 -5.777903472 24.99154777 0.903731277 0.772177874 0.296833608 0.101871061 271.1298597 411559.2104 0.017245765 0.031324361 1.67E-06 5.777903472 -0.131553403 SSSVGS(ph)S(ph)SSYPIS(ph)PAVSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 3 0 S(0.054)S(0.06)S(0.63)VGS(0.403)S(0.438)S(0.126)S(0.164)Y(0.128)PIS(0.987)PAVS(0.009)R 108.97 0.0020798 36212000 2190.1 1923.4 2126.2 2504.6 2743.4 2914.3 2590 2819.9 2568.1 1953 TRUE FALSE FALSE 2016.751274 2089.650125 2204.998842 2494.236629 2710.686747 2309.841329 2662.668429 3679.674529 2286.385855 2020.866605 0.997963581 1.034036646 1.091115483 1.234241104 1.341348677 1.142995447 1.317587427 1.820839891 1.131388806 1 10.98075838 -1 0.39663799 0.998838735 12.68581617 0.800017322 0.104623637 16.98631856 0.201617224 0.024161738 156.4542186 0.1 1 11.68697743 SSSVGSS(ph)SSYPISPAVSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 S(0.004)S(0.012)S(0.195)VGS(0.298)S(0.465)S(0.019)S(0.007)Y(0.002)PISPAVSR 154.88 5.55E-05 1858000000 1273.7 1042.5 1095.4 1271.7 962.02 1424.2 978.61 579.63 1402.8 1051.6 TRUE FALSE FALSE 1172.885301 1132.609055 1135.996488 1266.438042 950.5485398 1128.804866 1006.067163 756.3565187 1248.91635 1088.143022 1.077877887 1.040864144 1.043977184 1.163852561 0.873551106 1.037368106 0.924572545 0.695089252 1.147750181 1 10.08765248 -3.6937431 1.008075878 1.0405169 1.22E-14 0.676103478 0.075155998 2.030804176 0.721125667 0.009896684 3.011353432 0.000202422 3.6937431 -1.0405169 SSSVGSSS(ph)SYPISPAVSR ddPTM_HeLa_Curcumin_4h_R1 1 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 SSSVGS(0.005)S(0.085)S(0.455)S(0.455)YPISPAVSR 167.29 1.45E-05 3854200 773.32 1128.6 870.11 1006.1 940.19 620.3 729.82 697.88 1015.8 1057.3 TRUE FALSE FALSE 712.110906 1226.151155 902.357042 1001.937025 928.9788483 491.6427878 750.296785 910.6603994 904.3692814 1094.041096 0.650899595 1.120754201 0.824792638 0.915812969 0.849126099 0.449382376 0.685803109 0.832382259 0.82663191 1 10.09545122 -5.472671476 24.65932086 0.860215195 0.657251043 0.332832102 0.145396918 358.8441743 176245.8623 0.024308723 0.054355127 3.37E-06 5.472671476 -0.202964152 SSSVGSSSSYPIS(ph)PAVSR ddPTM_HeLa_Curcumin_4h_R1 3 SSSVGSSSSYPISPAVSR 18 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 SSSVGSSS(0.004)S(0.004)YPIS(0.992)PAVSR;SSSVGSSSSYPIS(1)PAVSR;SSSVGSSS(0.007)S(0.007)YPIS(0.985)PAVSR ;; 302.9 1.24E-96 344286000 3782.16 3394.01 3404.19 3492.97 3543.04 5140.6 4784.2 2951.99 3333.81 2950.21 TRUE FALSE FALSE 3482.798045 3687.373101 3530.352276 3478.517016 3500.791562 4074.381613 4918.431776 3852.038162 2968.099384 3052.729578 1.140879975 1.20789379 1.156457585 1.139477614 1.146774214 1.334668371 1.611158686 1.261834061 0.972277206 1 11.57588408 -1 0.16296079 0.970555745 2.873013801 0.603774492 0.108065659 29.84636129 0.305478783 0.179770261 13.75997315 0.1 1 1.902458056 SSSVLS(ph)LEGSEK ddPTM_HeLa_Curcumin_4h_R1 3 SSSVLSLEGSEK 12 0 A1L390-3;A1L390;A0A0U1RR71;G3V311;A1L390-2 A1L390-3 PLEKHG3 Pleckstrin homology domain-containing family G member 3 1 0 SSSVLS(0.968)LEGS(0.032)EK;S(0.001)S(0.006)S(0.266)VLS(0.726)LEGSEK;S(0.264)S(0.028)S(0.018)VLS(0.689)LEGSEK ;; 158.11 0.00027134 69203500 8542.1 6681.7 7236.3 7071.5 7188.5 8573.2 5972.1 4454.9 8598.6 6452.8 TRUE FALSE FALSE 7865.983771 7259.236375 7504.483644 7042.240007 7102.781832 6795.02168 6139.661053 5813.178502 7655.355093 6677.03432 1.1780655 1.087194708 1.123924677 1.054695793 1.063762966 1.017670624 0.91951917 0.870622828 1.146520255 1 12.70499174 -4.747910749 1.223561137 1.087974409 0.843040657 0.747172512 0.046460834 0.405759848 0.855454151 0.010030821 0.100459259 1.79E-05 4.747910749 -0.244933752 SSSVS(ph)PSASFR ddPTM_HeLa_Curcumin_4h_R1 3 SSSVSPSASFR 11 0 Q04727-4;Q04727;Q04727-3;H7C4W5;H7C4P7;Q5JSY7;Q04727-2 Q04727-4 TLE4 Transducin-like enhancer protein 4 1 0 SSS(0.012)VS(0.954)PS(0.034)ASFR;SSS(0.001)VS(0.992)PS(0.007)ASFR;S(0.021)SS(0.005)VS(0.948)PS(0.026)ASFR ;; 168.98 0.00024727 156452000 7989.8 6846.8 7292.4 7048.6 7092.1 8140.4 5690.9 5312.6 8455.9 6846.6 TRUE FALSE FALSE 7357.398899 7438.606883 7562.662759 7019.434761 7007.53134 6451.989279 5850.571338 6932.387284 7528.308926 7084.51884 1.038517797 1.049980535 1.067491375 0.990813197 0.989132995 0.910716652 0.825824798 0.978526198 1.062642234 1 12.79045416 -5.388635753 2.261075182 1.023673284 0.894552578 0.650051989 0.042116383 0.139127073 1.377047447 0.005815051 0.015631045 4.09E-06 5.388635753 -0.129120706 SSSVSPSSWKS(ph)PPAS(ph)PESWK ddPTM_HeLa_Curcumin_4h_R1 2 SSSVSPSSWKSPPASPESWK 20 1 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 2 0 SSSVS(0.004)PS(0.023)S(0.026)WKS(0.948)PPAS(0.911)PES(0.088)WK;SSS(0.001)VS(0.05)PS(0.255)S(0.233)WKS(0.795)PPAS(0.607)PES(0.058)WK ; 94.301 0.00064739 139451000 7280.1 5054.4 5599.6 6091.7 5444.2 7112.7 5601.5 4813.9 6860.1 6518 TRUE FALSE FALSE 6703.872403 5491.279814 5807.126102 6066.494159 5379.281471 5637.445843 5758.663014 6281.63595 6107.564193 6744.500015 0.993976186 0.814186345 0.861016545 0.899472777 0.797580467 0.83585823 0.853830974 0.931371627 0.905562188 1 12.71949578 -7.272738139 24.52777254 0.997155428 0.854911919 0.512925525 0.046460978 181.0852755 393105.9062 0.006000715 0.006895884 5.34E-08 7.272738139 -0.142243508 SSSYADPWT(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 1 SSSYADPWTPPR 12 0 A0A0C4DGA7;O94929-2;O94929-3;O94929;A0A0A0MRD5;O94929-4 A0A0C4DGA7 ABLIM3 Actin-binding LIM protein 3 1 0 SSSYADPWT(1)PPR 145.83 0.0023994 27361000 685.32 662.82 582.11 606.03 775.75 1241.1 961.48 379.74 836.45 693.99 TRUE FALSE FALSE 631.0761989 720.1112073 603.6835087 603.5224084 766.4996879 983.6818699 988.4565411 495.5209779 744.6935277 718.1061008 0.878806346 1.002792215 0.840660604 0.840436264 1.067390581 1.369828036 1.376477014 0.690038669 1.037024371 1 9.488053209 -5.533375657 9.381916674 0.93233918 1.176914867 0.203745226 0.188231335 0.165858137 123.0802349 0.025377438 0.051668526 2.93E-06 5.533375657 0.244575686 SQS(ph)SDLLER ddPTM_HeLa_Curcumin_4h_R1 2 SQSSDLLER 9 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 S(0.016)QS(0.939)S(0.045)DLLER;S(0.001)QS(0.527)S(0.472)DLLER ; 115.34 0.0074415 69165000 2880.9 2153.9 2294.5 2421.1 2663.3 7356.5 7030.8 18278.6 3832.3 2552.1 TRUE FALSE FALSE 2652.873725 2340.073518 2379.536188 2411.08213 2631.541887 5830.678975 7228.065326 23851.661 3411.906278 2640.785285 1.004577593 0.8861279 0.901071436 0.913017103 0.996499754 2.207933757 2.737089368 9.032033437 1.292004427 1 11.36675129 -3.317420996 1.089595506 0.976464318 54.06034475 0.984627454 0.296196724 0.775144985 0.155049887 0.039398682 77.37218254 0.000481481 3.317420996 53.08388043 up SST(ph)DFSELEQPR ddPTM_HeLa_Curcumin_4h_R1 2 SSTDFSELEQPR 12 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 S(0.111)S(0.111)T(0.778)DFSELEQPR;SST(1)DFSELEQPR ; 276.12 4.29E-58 148812000 4732.4 5248 5097.7 5541 5072.7 8983.9 6908 2506.5 4437.7 6226.7 TRUE FALSE FALSE 4357.825546 5701.613735 5286.625246 5518.07281 5012.211366 7120.537871 7101.819888 3270.720311 3950.895413 6443.077362 0.676357787 0.884920887 0.820512459 0.856434356 0.777921959 1.105145487 1.102240357 0.507633252 0.613200058 1 12.6535342 APVPEPGLDLSLSPRPDS(ph)PQPR ddPTM_HeLa_Curcumin_4h_R1 3 APVPEPGLDLSLSPRPDSPQPR 22 1 Q8TAP8 Q8TAP8 PPP1R35 Protein phosphatase 1 regulatory subunit 35 1 0 APVPEPGLDLSLS(0.005)PRPDS(0.995)PQPR;APVPEPGLDLSLSPRPDS(0.999)PQPR;APVPEPGLDLS(0.002)LS(0.012)PRPDS(0.986)PQPR ;; 105.65 1.90E-05 293621000 6741.5 5552.3 5530.4 5745.9 5400.7 7110.9 4927.6 1672.25 6545.7 5823.3 TRUE FALSE FALSE 6207.903161 6032.216071 5735.361489 5722.124988 5336.30018 5636.019184 5065.855194 2182.111327 5827.653087 6025.659242 1.030244644 1.001088151 0.951823072 0.949626383 0.885596076 0.935336526 0.840713852 0.36213653 0.967139503 1 12.55690337 -4.136450381 1.500866959 0.995210425 3.12E-23 0.94275238 0.044152263 0.270088957 0.439355709 0.007338892 0.432953065 7.30E-05 4.136450381 -0.995210425 down SST(ph)PLHSPSPIR ddPTM_HeLa_Curcumin_4h_R1 1 SSTPLHSPSPIR 12 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 0 SS(0.07)T(0.929)PLHSPS(0.001)PIR 187.58 4.88E-05 59957000 2138.5 1792.1 1312 1666.5 1848.4 2592.8 1754.7 404.34 2391.9 1696.2 TRUE FALSE FALSE 1969.235468 1947.001139 1360.623874 1659.604465 1826.359037 2055.024053 1803.932159 527.6214046 2129.514554 1755.142824 1.121980184 1.109312081 0.77522117 0.945566618 1.040575737 1.170858591 1.027797929 0.300614513 1.213299867 1 10.77737272 -4.261917906 7.045689005 1.041120253 0.290061687 0.781778666 0.117982298 0.03475039 13.403602 0.015372074 0.124216395 5.47E-05 4.261917906 -0.751058565 CSVGTYNS(ph)SGAYR ddPTM_HeLa_Curcumin_4h_R1 1 CSVGTYNSSGAYR 13 0 E9PEW5;A0A0A0MQX1;Q9HD67-3;Q9HD67 E9PEW5 MYO10 Unconventional myosin-X 1 0 CSVGT(0.002)YNS(0.965)S(0.033)GAYR 156.2 0.00036589 8811600 1406.4 968.6 969.65 1291.2 1304.6 1268.2 986.45 352.05 1624.5 1336.1 TRUE FALSE FALSE 1295.081956 1052.321468 1005.586082 1285.857357 1289.043497 1005.161024 1014.127132 459.3884244 1446.296414 1382.529376 0.936748238 0.761156679 0.727352416 0.930075975 0.932380548 0.727044967 0.73353026 0.332281131 1.04612346 1 10.43309442 -4.135788155 0.82063409 0.936202488 2.91E-46 0.721061042 0.103952928 1.164131128 0.495105667 0.017520495 1.035257389 7.31E-05 4.135788155 -0.936202488 down SST(ph)PLSEAK ddPTM_HeLa_Curcumin_4h_R1 1 SSTPLSEAK 9 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 S(0.001)S(0.001)T(0.997)PLSEAK 157.75 0.0029037 148370000 9703.7 8332.1 8384.8 9016.1 9554 16095 15555 4942.5 9088.4 5660.5 TRUE FALSE FALSE 8935.641906 9052.289597 8695.548064 8978.793767 9440.07479 12756.71557 15991.43144 6449.445498 8091.425258 5857.201954 1.525582006 1.545497264 1.484590788 1.532949323 1.611703825 2.177953855 2.730216845 1.101113731 1.381448911 1 12.51599592 -7.466782252 0.185523404 0.695230911 2.286536371 0.238754646 0.41786024 2.333228988 0.39909045 1.500392352 1.412078566 3.41E-08 7.466782252 1.59130546 SST(ph)PPGESYFGVSSLQLK ddPTM_HeLa_Curcumin_4h_R1 2 SSTPPGESYFGVSSLQLK 18 0 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 S(0.068)S(0.068)T(0.865)PPGESYFGVSSLQLK;S(0.01)S(0.01)T(0.981)PPGESYFGVSSLQLK ; 152.68 0.00018601 2152900000 6797.4 5403 5305 5403.9 5242.9 8295.7 6493 4961.9 5920 5716.4 TRUE FALSE FALSE 6259.378617 5870.011245 5501.607967 5381.540094 5180.381842 6575.078308 6675.176105 6474.760468 5270.590811 5915.044475 1.05821328 0.992386663 0.930104244 0.909805517 0.875797615 1.111585608 1.128508185 1.09462583 0.891048382 1 12.5301733 -5.06897553 24.99890909 0.999848105 1.11368826 0.45832027 0.066515392 131.9536402 47823.87962 0.009736623 0.024823636 8.53E-06 5.06897553 0.113840154 SST(ph)PPRQS(ph)PS(ph)RS(ph)SSPQPK ddPTM_HeLa_Curcumin_4h_R1 1 SSTPPRQSPSRSSSPQPK 18 2 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 4 0 S(0.132)S(0.175)T(0.699)PPRQS(0.987)PS(0.74)RS(0.464)S(0.422)S(0.379)PQPK 55.02 0.015126 17404000 3479 2938.3 3245.8 3673.6 3588.6 5397.2 5001 4014.9 3664.8 3577.9 TRUE FALSE FALSE 3203.633479 3192.273559 3366.092203 3658.399617 3545.808289 4277.759881 5141.3146 5239.024528 3262.780609 3702.231759 0.865324941 0.862256543 0.909206236 0.988160616 0.957748871 1.155454375 1.388706849 1.415099018 0.881301016 1 11.8541795 -4.965636432 1.729671538 0.929359138 1.435738488 0.948014863 0.045085751 0.078671945 0.434592936 0.008698289 0.041698117 1.08E-05 4.965636432 0.50637935 SST(ph)PSPSPLNLSSSR ddPTM_HeLa_Curcumin_4h_R1 1 SSTPSPSPLNLSSSR 15 0 P37275-3;P37275-4;P37275-5;P37275;P37275-2 P37275-3 ZEB1 Zinc finger E-box-binding homeobox 1 1 0 S(0.015)S(0.015)T(0.962)PS(0.008)PSPLNLSSSR 109.99 0.0064673 8725300 1113.4 997.98 1018 1094.5 1260.9 1600.7 1062 297.32 1566.8 1068.2 TRUE FALSE FALSE 1025.273215 1084.240944 1055.727976 1089.971249 1245.864591 1268.696776 1091.796862 387.9714993 1394.92596 1105.31987 0.927580552 0.980929569 0.955133445 0.986113865 1.127152985 1.147809616 0.987765525 0.351003822 1.262011113 1 10.11024822 -4.261568892 9.397387703 0.990880352 0.348776857 0.768689042 0.110543798 0.021056777 45.26534747 0.011075032 0.085998142 5.48E-05 4.261568892 -0.642103494 SST(ph)VASLDTDSTK ddPTM_HeLa_Curcumin_4h_R1 1 SSTVASLDTDSTK 13 0 C9IZZ8;C9J6Y2;C9J0J6;C9JZ07;G3V1A3;C9J5T5;C9JBU8;A8MPU2;O14713-2;O14713 C9IZZ8 ITGB1BP1 Integrin beta-1-binding protein 1 1 0 S(0.001)S(0.002)T(0.833)VAS(0.163)LDTDSTK 171.99 0.00058476 41513000 7023.6 5529.5 6413.7 6761.9 6238.3 7225.8 5391 3276.4 7892.6 5947.6 TRUE FALSE FALSE 6467.674649 6007.445341 6651.397364 6733.921049 6163.912347 5727.087628 5542.256951 4275.359277 7026.801526 6154.278657 1.05092327 0.976141263 1.080776113 1.094185269 1.001565365 0.930586336 0.900553462 0.694697058 1.141775002 1 12.58737405 -4.035281638 0.992284687 1.029307892 0.397078817 0.814320019 0.051873559 0.706911209 0.398798665 0.006231674 0.527735021 9.22E-05 4.035281638 -0.632229076 SSTAISSIAADGEFLHELEEK ddPTM_HeLa_Curcumin_4h_R1 2 SSTAISSIAADGEFLHELEEK 21 0 E9PF10;O75694-2;O75694 E9PF10 NUP155 Nuclear pore complex protein Nup155 0 0 ; ; 108.13 4.06E-05 4941300 1609.95 1508.86 1302.36 1481.07 1746.61 1564.55 1236.17 731.66 1987.55 1328.2 FALSE FALSE TRUE 1482.520759 1639.279135 1350.626607 1474.941725 1725.782816 1240.044694 1270.853603 954.7397659 1769.520738 1374.354851 1.078703042 1.192762651 0.982734995 1.07318843 1.255703951 0.902274033 0.92469103 0.694682138 1.28752828 1 10.42453883 -4.407897858 1.490523892 1.059164284 0.625752656 0.532770247 0.116426417 0.455759002 1.129887875 0.013368357 0.266797841 3.91E-05 4.407897858 -0.433411628 SSTETCY(ph)SAIPK ddPTM_HeLa_Curcumin_4h_R1 1 SSTETCYSAIPK 12 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;A0A0A0MT44 O75369-8 FLNB Filamin-B 1 0 SSTET(0.088)CY(0.889)S(0.022)AIPK 185.96 0.00021636 29546000 2834.4 3992.6 2091.3 2151.9 1889.6 4065 1553.2 268.23 5494.8 2079.4 TRUE FALSE FALSE 2610.054249 4337.702553 2168.805418 2142.996008 1867.067754 3221.873178 1596.778612 350.0120922 4892.034187 2151.658995 1.213042706 2.015980489 1.007968931 0.99597381 0.867734041 1.497390239 0.742115091 0.162670801 2.273610362 1 11.07123374 -4.438644103 3.378103227 1.158661044 0.175374643 0.335151361 0.476611294 0.171880795 3.376117808 0.044792157 0.330830978 3.64E-05 4.438644103 -0.983286401 SSTETCYSAIPK ddPTM_HeLa_Curcumin_4h_R1 2 SSTETCYSAIPK 12 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;A0A0A0MT44 O75369-8 FLNB Filamin-B 0 0 ; ; 200.71 5.19E-15 9877200 5662.6 4163.9 4875.7 5029.2 4813.1 5714.1 4382.6 4107.8 5730 4618.6 FALSE FALSE TRUE 5214.399235 4523.808962 5056.397731 5008.390503 4755.706926 4528.931249 4505.563961 5360.24931 5101.433336 4779.096006 1.091084847 0.946582566 1.058023887 1.047978634 0.995105961 0.947654377 0.942764898 1.121603187 1.067447343 1 12.22252203 -5.75069575 22.38761985 1.037539351 0.993700269 0.063676113 0.059201615 109.8775361 228955.6793 0.008797273 0.01741362 1.78E-06 5.75069575 -0.043839082 SSTFPQTDVLSSS(ph)LEAEHR ddPTM_HeLa_Curcumin_4h_R1 2 SSTFPQTDVLSSSLEAEHR 19 0 D4PHA4;Q86WP2-4;Q86WP2-3;Q86WP2;Q86WP2-2 D4PHA4 GPBP1 Vasculin 1 0 SSTFPQTDVLS(0.005)S(0.151)S(0.844)LEAEHR;SSTFPQTDVLS(0.002)S(0.228)S(0.77)LEAEHR ; 242.11 1.07E-33 97616000 11403.4 10447.5 10424.7 10260.5 11045.3 13253.3 8322.3 5780.9 13007.1 9647.4 TRUE FALSE FALSE 10500.80886 11350.53535 10811.04855 10218.04477 10913.59201 10504.41618 8555.80134 7543.469798 11580.25367 9982.646432 1.051906319 1.137026682 1.082984219 1.023580755 1.093256391 1.052267678 0.857067452 0.755658317 1.160038448 1 13.28520661 -4.629025499 3.244506241 1.043818312 0.770393457 0.791524818 0.05431629 0.07472969 1.481518489 0.006758909 0.033214298 2.35E-05 4.629025499 -0.273424855 SSTGEAT(ph)WS(ph)GWLKMR ddPTM_HeLa_Curcumin_4h_R1 1 SSTGEATWSGWLKMR 15 1 F5GWJ5;Q96MS0-2;Q96MS0 F5GWJ5 ROBO3 Roundabout homolog 3 2 0 SST(0.001)GEAT(0.999)WS(0.999)GWLKMR 87.913 0.005389 0 2696.2 2125.8 2655.5 2298.6 2523.2 2366.9 2022.5 1911.2 2514.5 2096.3 TRUE FALSE FALSE 2482.792925 2309.54468 2753.915166 2289.089002 2493.112488 1875.97826 2079.245907 2493.916082 2238.665641 2169.146269 1.144594517 1.064725193 1.269584816 1.055294903 1.149351947 0.864846362 0.958554956 1.149722413 1.032049186 1 11.08291162 -5.286481034 24.98395002 1.088638013 0.987792558 0.206806269 0.097207785 980.0453969 977785.7059 0.014553088 0.032552924 5.17E-06 5.286481034 -0.100845456 RES(ph)LGLESK ddPTM_HeLa_Curcumin_4h_R1 1 RESLGLESK 9 1 Q96BH1 Q96BH1 RNF25 E3 ubiquitin-protein ligase RNF25 1 0 RES(0.999)LGLES(0.001)K 81.565 0.014259 27452000 4446.8 4124.2 4410.7 4282 4769.6 7674.8 7887.9 11699 5578.4 4057.8 TRUE FALSE FALSE 4094.831088 4480.677471 4574.164422 4264.282219 4712.725635 6082.959967 8109.213245 15265.97124 4966.463476 4198.808248 0.975236507 1.067130768 1.089395884 1.015593465 1.122396013 1.448734881 1.931313069 3.635786714 1.182826932 1 12.03576419 -3.308011317 0.881473586 0.998265918 14.47132286 0.989840778 0.078600209 0.430884557 0.071506585 0.008653366 8.368742282 0.000492027 3.308011317 13.47305695 up SSTIFKT(ph)T(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SSTIFKTTK 9 1 O94916-2;O94916;O94916-4;O94916-5 O94916-2 NFAT5 Nuclear factor of activated T-cells 5 2 0 SSTIFKT(1)T(1)K 153.04 0.0012985 13875000 2478.3 2006.4 2581.8 2136 2176.3 3102.7 2457.4 2419.9 2271.1 2634.3 TRUE FALSE FALSE 2282.13994 2179.824276 2677.483779 2127.161798 2150.349044 2459.165045 2526.34803 3157.71637 2021.966012 2725.841729 0.837223936 0.799688497 0.982259443 0.780368785 0.788875238 0.902167217 0.92681391 1.158437167 0.741776748 1 11.41248608 -4.25300219 3.296968178 0.896359933 1.197027881 0.46478394 0.089390972 0.255301332 4.392820155 0.012586728 0.196402166 5.58E-05 4.25300219 0.300667948 (ac)ATDELATKLS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 ATDELATKLSR 11 1 Q96C19 Q96C19 EFHD2 EF-hand domain-containing protein D2 1 0 ATDELAT(0.027)KLS(0.973)R;ATDELAT(0.112)KLS(0.888)R ; 76.24 0.0024264 43599000 4482.3 3980 4055.5 4226.4 3900.1 4801.2 3811.4 1124.74 4079.2 4438.3 TRUE FALSE FALSE 4127.521225 4324.013465 4205.800398 4208.912277 3853.593855 3805.376999 3918.337626 1467.668048 3631.721966 4592.530595 0.898746593 0.941531771 0.915791482 0.916469077 0.839100312 0.828601339 0.853197936 0.319577196 0.790788845 1 12.16507362 -4.134311277 1.84278519 0.9327775 1.60E-27 0.855825086 0.068303721 0.284798717 0.745470558 0.008947618 0.507665571 7.34E-05 4.134311277 -0.9327775 down SSTPEEVK ddPTM_HeLa_Curcumin_4h_R1 2 SSTPEEVK 8 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;E9PS23 P23528 CFL1 Cofilin-1 0 0 ; ; 109.21 0.0069383 26212000 13555.6 16163.2 12572 11299.6 12181.8 15596 11859.8 11174.2 12025.5 12470 FALSE FALSE TRUE 12482.65996 17560.27499 13037.92938 11252.84525 12036.53999 12361.2138 12192.55407 14581.16214 10706.33274 12903.33157 0.967398217 1.360910156 1.010431245 0.872088358 0.932824203 0.957986217 0.944915195 1.130030803 0.829733986 1 13.65545599 -6.495292098 24.62967692 1.02064856 0.961588975 0.04929226 0.138920735 1733.025827 1547265.362 0.020065408 0.03059745 3.20E-07 6.495292098 -0.059059585 SSTPLHS(ph)PSPIR ddPTM_HeLa_Curcumin_4h_R1 2 SSTPLHSPSPIR 12 0 O95817;C9JFK9 O95817 BAG3 BAG family molecular chaperone regulator 3 1 0 S(0.001)S(0.002)T(0.029)PLHS(0.952)PS(0.017)PIR;S(0.001)S(0.004)T(0.006)PLHS(0.774)PS(0.216)PIR ; 98.654 0.0047498 26895000 4588.8 3468.3 3054.7 3585.7 4511.9 4982.1 3406.9 2803.5 4190.6 3438.2 TRUE FALSE FALSE 4225.591638 3768.084398 3167.909869 3570.863323 4458.098539 3948.7563 3502.488445 3658.274244 3730.901664 3557.677194 1.187738911 1.059141735 0.890443314 1.003706387 1.25309248 1.109925405 0.984487421 1.028276048 1.048690328 1 11.7967199 -7.015592467 24.79645308 1.090485318 1.046274586 0.019081789 0.098211395 2174.994209 3458854.402 0.019003868 0.023665844 9.65E-08 7.015592467 -0.044210732 SSTPLPTISSS(ph)AENTR ddPTM_HeLa_Curcumin_4h_R1 1 SSTPLPTISSSAENTR 16 0 G5E972;P42167;H0YJH7;P42167-3;P42167-2;P42166 G5E972;P42166 TMPO "Lamina-associated polypeptide 2, isoforms beta/gamma;Thymopoietin;Thymopentin;Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin" 1 0 SSTPLPTIS(0.015)S(0.232)S(0.753)AENTR 137.27 0.00041485 11394000 3369.7 2681.4 3274.4 3588.5 3775.2 5114.4 4000.4 4387.3 3330.8 3424.7 TRUE FALSE FALSE 3102.984689 2913.168268 3395.752144 3573.651738 3730.183206 4053.615789 4112.640457 5724.967573 2965.419573 3543.70807 0.875632142 0.822067792 0.958248275 1.008449812 1.052621472 1.143891006 1.160547194 1.615530247 0.836812603 1 11.79104404 -1 0.609192613 0.933811045 45.82577502 0.903385409 0.068187794 36.80307023 0.254326119 0.012661644 2211.375076 0.1 1 44.89196398 SSTTVSSFANSKPGSAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 SSTTVSSFANSKPGSAKK 18 2 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 0 1 SSTTVSSFANSKPGSAK(1)K 179.74 4.28E-08 4186800 1666.6 1699.2 1688.4 1535.8 1781.6 1755.8 1064.5 1101.9 1794.5 1765.6 FALSE TRUE FALSE 1534.686851 1846.071277 1750.973589 1529.445267 1760.355584 1391.627288 1094.367005 1437.864237 1597.64784 1826.954469 0.840024685 1.010463757 0.958411181 0.837155656 0.9635465 0.761719743 0.599011647 0.787027954 0.874486949 1 10.83522496 -5.120352945 4.116142728 0.927418409 0.690026764 0.649484233 0.071726322 0.110146903 3.142891684 0.01110375 0.030418464 7.58E-06 5.120352945 -0.237391645 SSTVATLQGT(ph)PDHGDPR ddPTM_HeLa_Curcumin_4h_R1 2 SSTVATLQGTPDHGDPR 17 0 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 SSTVATLQGT(1)PDHGDPR;SST(0.001)VAT(0.012)LQGT(0.987)PDHGDPR ; 110.6 0.0010837 63229000 4141.4 3779.9 3547.8 3674.2 4589.4 9440.9 9539.4 3995.7 4763.9 3432.7 TRUE FALSE FALSE 3813.60382 4106.617713 3679.284589 3658.997134 4534.674402 7482.750919 9807.04989 5213.970536 4241.312089 3551.986069 1.073653935 1.156146908 1.035838688 1.030127107 1.276658836 2.106638588 2.761004604 1.467902867 1.194067771 1 11.79441021 -5.315647298 3.423225516 1.048943687 2.192537545 0.704580222 0.298110032 0.079085128 1.86196471 0.037625097 0.093830038 4.83E-06 5.315647298 1.143593858 SSTYEVR ddPTM_HeLa_Curcumin_4h_R1 2 SSTYEVR 7 0 A0A096LNZ9;A0A096LPJ4;P05161 A0A096LNZ9 ISG15 Ubiquitin-like protein ISG15 0 0 ; ; 114.19 0.011148 3822300 5467.3 5227 5612.2 5350.8 5609.4 6826.6 5593.6 5156.8 5987.8 6021.1 FALSE FALSE TRUE 5034.557436 5678.798589 5820.193069 5328.659807 5542.511569 5410.686208 5750.541362 6729.084581 5330.953321 6230.332777 0.808071995 0.911475966 0.934170497 0.855276917 0.889601209 0.86844257 0.922991045 1.080052193 0.855645037 1 12.60509351 -4.270560089 3.984329309 0.901826205 1.094713114 0.55219447 0.050161147 0.193640049 6.350077806 0.009815663 0.10614117 5.36E-05 4.270560089 0.192886909 SSVKT(ph)PETVVPTALELQPSTSTDRPVTSEPTSQATR ddPTM_HeLa_Curcumin_4h_R1 1 SSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATR 36 2 Q14676;Q14676-2;H0Y6Z8 Q14676 MDC1 Mediator of DNA damage checkpoint protein 1 1 0 S(0.043)S(0.043)VKT(0.672)PET(0.222)VVPT(0.019)ALELQPSTSTDRPVTSEPTSQATR 54.241 0.00034492 27868000 2417.8 1754.5 2120 2490.8 2500.9 3224.9 2188.7 2268 2846.8 2232.6 TRUE FALSE FALSE 2226.428579 1906.151162 2198.569065 2480.49373 2471.078401 2556.019388 2250.109031 2959.502759 2534.513162 2310.182684 0.963745679 0.82510841 0.951686237 1.073721895 1.069646318 1.1064144 0.973996146 1.281068714 1.097105082 1 11.17379123 -6.180662888 4.387890881 0.966004953 1.094932942 0.335022991 0.094121429 0.193968466 6.906220499 0.012472027 0.020971178 6.60E-07 6.180662888 0.128927989 SSVLPS(ph)PSGR ddPTM_HeLa_Curcumin_4h_R1 1 SSVLPSPSGR 10 0 A0A494C1F2;P35658-2;P35658;P35658-5;A0A0A0MSW3;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 0 SSVLPS(0.991)PS(0.009)GR 122.18 0.0041893 18499000 2368.2 1659.8 2321.6 2307.6 2486.7 2950.9 2930.2 2896.9 2758.5 1947 TRUE FALSE FALSE 2180.754471 1803.265716 2407.640538 2298.051763 2457.047727 2338.850077 3012.413526 3780.151474 2455.899451 2014.658105 1.082443947 0.895072822 1.1950616 1.140665881 1.219585457 1.160916619 1.495248012 1.87632406 1.219015497 1 10.97631931 -1 0.540721456 1.034582517 37.26718507 0.860003114 0.098221417 21.34502539 0.183252239 0.014448681 899.1020861 0.1 1 36.23260255 SSVLPSPS(ph)GR ddPTM_HeLa_Curcumin_4h_R1 1 SSVLPSPSGR 10 0 A0A494C1F2;P35658-2;P35658;P35658-5;A0A0A0MSW3;A0A494BZU9 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 0 SSVLPS(0.46)PS(0.54)GR 91.123 0.018468 46143000 1476.1 1374.8 1573.4 1345.6 1349.7 2134.4 1605.4 1564.2 1539.7 1785.5 TRUE FALSE FALSE 1359.265127 1493.631586 1631.711588 1340.032264 1333.605709 1691.70138 1650.443203 2041.117379 1370.798762 1847.545992 0.735713824 0.808440814 0.883177791 0.725303873 0.721825446 0.915647777 0.893316437 1.104772162 0.741956502 1 10.85139456 -4.11375325 1.76941822 0.848735374 1.265659967 0.443349209 0.092299658 1.37407953 3.121596388 0.016696492 1.077931887 7.70E-05 4.11375325 0.416924594 SSVSEGIR ddPTM_HeLa_Curcumin_4h_R1 1 SSVSEGIR 8 0 B7Z2Y2;Q14746-2;Q14746 B7Z2Y2 COG2 Conserved oligomeric Golgi complex subunit 2 0 0 93.195 0.01964 8447400 8480.8 7681.7 7561.4 7683.5 8073.7 2236.5 4702 1121.8 8881.2 7619 FALSE FALSE TRUE 7809.535731 8345.671919 7841.632136 7651.707713 7977.426401 1772.624689 4833.925465 1463.831656 7906.95458 7883.759683 0.990585209 1.05859035 0.994656414 0.970565824 1.011880971 0.224845094 0.613149774 0.185676849 1.002942111 1 12.94466808 -5.268758841 24.99615862 0.999258223 0.368416486 0.885943425 0.108864297 109.7039723 374642.4036 0.013279825 0.030264537 5.39E-06 5.268758841 -0.630841737 SSWLEEDDDPVVAR ddPTM_HeLa_Curcumin_4h_R1 1 SSWLEEDDDPVVAR 14 0 O15460-2;O15460 O15460-2 P4HA2 Prolyl 4-hydroxylase subunit alpha-2 0 0 215.08 7.33E-13 6368900 1166.9 580.59 888.33 842.43 855.71 997.77 676.56 644.45 1011.2 846.96 FALSE FALSE TRUE 1074.538634 630.7736125 921.2522913 838.9442479 845.5062171 790.8212548 695.5424527 840.9398383 900.2738899 876.391797 1.226093897 0.719739293 1.051187716 0.957270767 0.964758251 0.902360403 0.793643271 0.95954782 1.027250475 1 9.775432171 -7.275189906 24.91776772 1.106766559 0.912105492 0.370669779 0.104642646 578.2860934 1047928.381 0.01987726 0.02279517 5.31E-08 7.275189906 -0.194661068 SSYDMYHLSRERGAHER ddPTM_HeLa_Curcumin_4h_R1 1 SSYDMYHLSRERGAHER 17 2 A0A1W2PRK8;Q15702;Q5UCE1 A0A1W2PRK8 KIR3DL1 0 0 66.246 0.0075396 0 1676.5 1780.3 3057.1 2156.2 4212.3 5643.7 3522 2848.1 4719.7 2262.2 FALSE FALSE TRUE 1543.803256 1934.181199 3170.398815 2147.278216 4162.071074 4473.133002 3620.817841 3716.472579 4201.960718 2340.811282 0.659516326 0.826286687 1.354401715 0.917322226 1.778046401 1.910932777 1.546821766 1.587685692 1.795087349 1 11.19279291 -6.010792826 1.379431984 0.846902606 1.715292207 0.256980316 0.370798542 0.160180939 0.605095268 0.037941073 0.082490881 9.75E-07 6.010792826 0.868389601 SSYLES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SSYLESPR 8 0 H0YIQ2;P49750-3;P49750-1;P49750;F8VU51 H0YIQ2 YLPM1 YLP motif-containing protein 1 1 0 SSY(0.001)LES(0.999)PR 104.42 0.012925 26247000 2043.4 2335.4 2118 2368.7 2428.2 3509.4 3299.6 2763.5 1987.8 2038.6 TRUE FALSE FALSE 1881.662734 2537.26157 2196.494943 2358.898947 2399.245301 2781.510881 3392.177896 3606.078428 1769.743313 2109.441198 0.892019524 1.202812182 1.041268628 1.11825774 1.1373843 1.318600814 1.608093128 1.709494643 0.838963093 1 11.04264516 -4.286140901 0.530438216 0.958063886 2.304938373 0.897366472 0.087114746 0.782391738 0.149699448 0.017218684 0.647295681 5.17E-05 4.286140901 1.346874487 SSYVFS(ph)PESEVSAPGVSEDALKPQEGK ddPTM_HeLa_Curcumin_4h_R1 2 SSYVFSPESEVSAPGVSEDALKPQEGK 27 1 A0A5F9ZGT0;H0Y9K9;G5E9Z1;A0A590UJE4;A0A494C0H4;H0Y9M2;Q17R98-3;Q17R98-2;Q17R98 A0A5F9ZGT0 ZNF827 Zinc finger protein 827 1 0 S(0.003)S(0.003)Y(0.009)VFS(0.473)PES(0.412)EVS(0.1)APGVSEDALKPQEGK;S(0.025)S(0.025)Y(0.001)VFS(0.876)PES(0.07)EVS(0.002)APGVSEDALKPQEGK ; 71.299 0.00016415 10001700 2847.5 2422.88 2368.94 2851.2 2722.5 4076 3469.2 2070.53 3387.1 2593.8 TRUE FALSE FALSE 2622.11737 2632.302951 2456.735 2839.40249 2690.035966 3230.591654 3566.536415 2701.825065 3015.543604 2683.934357 0.976967773 0.980762791 0.915348393 1.05792546 1.002273382 1.203677596 1.328846365 1.006665852 1.123553412 1 11.39013367 -5.279854054 6.163394424 0.988331612 1.195183957 0.414989234 0.090769656 0.079065583 12.40453914 0.010273718 0.024106166 5.25E-06 5.279854054 0.206852344 ST(ph)GVVNIPAAECLDEYEDDEAGQKER ddPTM_HeLa_Curcumin_4h_R1 1 STGVVNIPAAECLDEYEDDEAGQKER 26 1 Q96IZ0;H0YI16 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 1 0 S(0.461)T(0.539)GVVNIPAAECLDEYEDDEAGQKER 93.596 8.09E-06 13152000 477.48 549.82 564.33 481.79 590.37 669.66 310.62 288.53 496.2 331.11 TRUE FALSE FALSE 439.6869542 597.3439908 585.2445662 479.7964806 583.3302233 530.7649674 319.3351612 376.5014688 441.7681014 342.6160479 1.283322708 1.74347931 1.708164489 1.400391148 1.70257706 1.549153843 0.932049632 1.098902025 1.289396992 1 8.420448917 -8.126224524 1.235983666 1.061939847 1.443303174 0.142617155 0.264125937 0.397722716 1.255029376 0.071934097 0.056485414 7.48E-09 8.126224524 0.381363327 ST(ph)LIS(ph)S(ph)DGVS(ph)KK ddPTM_HeLa_Curcumin_4h_R1 1 STLISSDGVSKK 12 1 F8VY01;Q6ZV73-2;Q6ZV73 F8VY01 FGD6 "FYVE, RhoGEF and PH domain-containing protein 6" 4 0 S(0.11)T(0.894)LIS(0.998)S(0.997)DGVS(1)KK 57.034 0.015504 6459300 169.71 169.99 168.38 190.98 163.46 254.5 182.99 189.21 222.52 333.99 TRUE FALSE FALSE 156.2772744 184.6831781 174.6203109 190.1897754 161.5108463 201.7138312 188.1242069 246.899258 198.1101127 345.5961276 0.452196254 0.534390184 0.505272765 0.550323803 0.467339861 0.583669246 0.544346976 0.71441558 0.573241703 1 8.432943242 -9.301615032 0.9237914 1.012693418 0.536413129 0.074053821 0.146504543 0.169753734 0.248660195 0.056141208 0.013534112 4.99E-10 9.301615032 -0.476280289 ST(ph)LTQASSMTPHS(ph)GPR ddPTM_HeLa_Curcumin_4h_R1 1 STLTQASSMTPHSGPR 16 0 Q9H2D6-3;Q9H2D6-2;Q9H2D6;Q9H2D6-4 Q9H2D6-3 TRIOBP TRIO and F-actin-binding protein 2 0 S(0.09)T(0.437)LT(0.437)QAS(0.066)S(0.033)MT(0.056)PHS(0.88)GPR 40.278 0.019457 5492200 1736 1274.3 1444.7 1090.3 1592.2 3833.3 1950.6 2722.8 1961.3 1631.9 TRUE FALSE FALSE 1598.593768 1384.444814 1498.241853 1085.788627 1573.214055 3038.23037 2005.328586 3552.969186 1746.150297 1688.608404 0.946693008 0.819873223 0.887264241 0.64300795 0.93166305 1.799251007 1.187562837 2.104081194 1.034076517 1 10.72161908 -5.269306577 24.56753976 0.927616231 1.646024802 0.706686343 0.235515088 184.001659 574597.8438 0.030630292 0.069702827 5.38E-06 5.269306577 0.71840857 ANTIPIIGS(ph)PSSK ddPTM_HeLa_Curcumin_4h_R1 1 ANTIPIIGSPSSK 13 0 E9PGM7;O94988-6;O94988-5;O94988-1;O94988 E9PGM7 FAM13A Protein FAM13A 1 0 ANTIPIIGS(0.602)PS(0.316)S(0.081)K 104.55 0.0052159 15987000 4259.3 3347.5 3638.6 3419.5 3583.9 4613.2 3123.6 1053.7 4423 3556.4 TRUE FALSE FALSE 3922.171911 3636.842984 3773.449717 3405.351015 3541.164333 3656.370319 3211.239809 1374.968279 3937.807966 3679.984635 1.065812034 0.988276676 1.025398226 0.925370987 0.962276934 0.993583039 0.872623157 0.373634245 1.07006098 1 11.84548403 -4.134034641 1.781787939 1.015528392 6.85E-12 0.951894283 0.042379401 0.20166404 0.487112303 0.006644874 0.380912503 7.34E-05 4.134034641 -1.015528392 down ST(ph)PFIVPS(ph)SPTEQEGR ddPTM_HeLa_Curcumin_4h_R1 1 STPFIVPSSPTEQEGR 16 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 S(0.421)T(0.579)PFIVPS(0.577)S(0.42)PT(0.003)EQEGR 101.3 0.011572 2637500 1167.6 1348.6 1183.4 1358.9 1455.6 1377.2 1191.3 769.05 1230.6 1081.3 TRUE FALSE FALSE 1075.183228 1465.166975 1227.257845 1353.277232 1438.242921 1091.553196 1224.724672 1003.529805 1095.606259 1118.875095 0.960950184 1.309500034 1.096867605 1.209498038 1.285436532 0.975580922 1.094603569 0.896909592 0.979203366 1 10.12783327 ST(ph)S(ph)PAGQHHS(ph)PISSR ddPTM_HeLa_Curcumin_4h_R1 2 STSPAGQHHSPISSR 15 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 3 0 S(0.546)T(0.63)S(0.825)PAGQHHS(0.748)PIS(0.16)S(0.091)R;S(0.598)T(0.729)S(0.673)PAGQHHS(0.934)PIS(0.055)S(0.011)R ; 85.224 0.005797 29652000 5731.8 5676.6 5503.6 5373.6 5504.7 5932.8 4777.2 4164.7 6012.6 5434.4 TRUE FALSE FALSE 5278.121982 6167.26001 5707.568257 5351.365467 5439.060048 4702.270404 4911.235375 5434.497858 5353.032823 5623.244995 0.938625649 1.096743964 1.014995481 0.951650777 0.96724579 0.836220084 0.873381007 0.966434481 0.951947288 1 12.45718719 -5.414142445 6.124475463 0.982395761 0.89044226 0.417683738 0.052221841 0.193535563 9.399965642 0.00783066 0.017649746 3.85E-06 5.414142445 -0.091953501 ST(ph)SFRQGPEESGLGDGTGPK ddPTM_HeLa_Curcumin_4h_R1 1 STSFRQGPEESGLGDGTGPK 20 1 Q92614;A0A0D9SFK2;Q92614-2;Q92614-3;Q92614-4;Q92614-5 Q92614 MYO18A Unconventional myosin-XVIIIa 1 0 S(0.084)T(0.457)S(0.457)FRQGPEES(0.002)GLGDGTGPK 61.477 0.012169 47776000 1510.6 1136.1 1083 1265.5 1021.6 1864.6 1220.9 1118.2 1772.5 1481 TRUE FALSE FALSE 1391.034416 1234.299422 1123.136933 1260.263696 1009.418087 1477.860942 1255.155168 1459.134032 1578.061185 1532.46464 0.907710612 0.805434194 0.732895823 0.822377015 0.658689317 0.964368706 0.819043478 0.952148581 1.029753734 1 10.58163807 -7.749375491 1.315136805 0.974030637 0.8189308 0.404363397 0.088661616 0.291725534 1.049857863 0.019313393 0.018421116 1.78E-08 7.749375491 -0.155099837 GQTPLTEGSEDLDGHS(ph)DPEESFAR ddPTM_HeLa_Curcumin_4h_R1 1 GQTPLTEGSEDLDGHSDPEESFAR 24 0 K7EQI9;Q86VR2-2;Q86VR2 K7EQI9 FAM134C Protein FAM134C 1 0 GQTPLTEGS(0.003)EDLDGHS(0.997)DPEES(0.001)FAR 120.29 3.82E-07 19198000 1234.7 961.05 1073.5 1610.3 1721.7 2724.2 2055.5 2525.2 1444.1 1264.3 TRUE FALSE FALSE 1136.972192 1044.11888 1113.284854 1603.637005 1701.169852 2159.170212 2113.171798 3295.121855 1285.685843 1308.234331 0.869089096 0.798113041 0.850982754 1.22580257 1.30035561 1.650446071 1.615285387 2.518755071 0.982764183 1 10.35340526 -3.248423419 0.518989573 0.913651891 6.156659616 0.927395314 0.135782887 1.847647615 0.155298571 0.027847762 7.478971445 0.000564386 3.248423419 5.243007726 up ST(ph)VLGLPQHVQK ddPTM_HeLa_Curcumin_4h_R1 1 STVLGLPQHVQK 12 0 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 1 0 S(0.167)T(0.833)VLGLPQHVQK 139.78 0.0035544 11786000 1298.9 873.02 822.15 1089.2 975.09 1325 1480.9 945.55 976.6 1161.9 TRUE FALSE FALSE 1196.090694 948.4799587 852.6196022 1084.693179 963.4626886 1050.180064 1522.450068 1233.843842 869.4694233 1202.275939 0.994855387 0.788903719 0.70917131 0.902199856 0.801365691 0.873493372 1.266306693 1.026256787 0.723186247 1 10.23155234 -4.77137894 24.99985833 0.934543555 1.14628176 0.320358049 0.132634546 169.6933108 426814.8256 0.018664864 0.056977003 1.69E-05 4.77137894 0.211738205 STADS(ph)GGEGLETAPK ddPTM_HeLa_Curcumin_4h_R1 2 STADSGGEGLETAPK 15 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 STADS(1)GGEGLETAPK;S(0.024)T(0.278)ADS(0.697)GGEGLET(0.001)APK ; 115.04 0.0016983 43429000 7444.5 6327.2 6774.4 6410.7 7607.3 7940.3 6285 5810.1 7151 6802.5 TRUE FALSE FALSE 6855.25997 6874.094975 7025.465223 6384.174222 7516.587916 6293.392274 6461.340185 7581.572744 6366.553191 7038.886369 0.973912578 0.976588428 0.998093286 0.906986402 1.067866069 0.894089199 0.91794921 1.077098329 0.904483019 1 12.78113148 -9.207732732 0.5225458 1.00505474 0.972191631 0 0.065678717 5.007488824 1.946770434 0.083072198 0.014129637 6.20E-10 9.207732732 -0.032863109 STAGDTHLGGEDFDNR ddPTM_HeLa_Curcumin_4h_R1 7 STAGDTHLGGEDFDNR 16 0 P11142;E9PKE3;P11142-2;E9PN89;P54652 P11142;P54652 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 0 ;;;;;; ;;;;;; 248.67 4.11E-30 988903800 24878.6 21908.5 21789.1 23042.5 26787.3 34820.8 23465.7 23731.7 29235.2 23377.2 FALSE FALSE TRUE 22909.43256 23802.17312 22596.62321 22947.15624 26467.87894 27598.57357 24124.08439 30967.38608 26028.1717 24189.55596 0.9470795 0.983985533 0.934147913 0.948639003 1.094186226 1.140929317 0.997293395 1.28019655 1.07600866 1 14.56209667 -1 0.513652685 0.971945084 10.44320862 0.559990998 0.068570814 46.1340782 0.427338366 0.011599789 477.3129424 0.1 1 9.471263532 STALT(ph)S(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 STALTSR 7 0 J3KN16 J3KN16 KIAA0368 2 0 STALT(1)S(1)R 63.148 0.018027 1953300 125.1 94.914 0 262.93 0 160.82 68.217 0 176.02 0 TRUE FALSE FALSE 115.198203 103.1179432 0 261.8420653 0 127.4641192 70.13098542 0 156.7110464 0 0 STAQQELDGKPAS(ph)PTPVIVASHTANK ddPTM_HeLa_Curcumin_4h_R1 1 STAQQELDGKPASPTPVIVASHTANK 26 1 H0YAC7;P35606-2;P35606 H0YAC7 COPB2 Coatomer subunit beta 1 0 S(0.005)T(0.005)AQQELDGKPAS(0.706)PT(0.282)PVIVAS(0.001)HTANK 58.249 0.0019526 18615000 5868.3 6034.8 6112.7 6086.9 6099.8 6070.4 4760.5 4542.9 5541.2 5453.6 TRUE FALSE FALSE 5403.817863 6556.421221 6339.242039 6061.714021 6027.063869 4811.330612 4894.066818 5928.009297 4933.344223 5643.112194 0.957595326 1.161844917 1.123359207 1.074179249 1.068038994 0.852602331 0.867263781 1.050485812 0.874224019 1 12.46227532 -5.266414289 24.98913404 1.01689166 0.917831955 0.217702959 0.093171476 516.3578785 2593687.312 0.01319022 0.030393117 5.41E-06 5.266414289 -0.099059705 STAQQELDGKPAS(ph)PTPVIVASHTANKEEK ddPTM_HeLa_Curcumin_4h_R1 3 STAQQELDGKPASPTPVIVASHTANKEEK 29 2 H0YAC7;P35606-2;P35606 H0YAC7 COPB2 Coatomer subunit beta 1 0 STAQQELDGKPAS(0.781)PT(0.217)PVIVAS(0.001)HTANKEEK;STAQQELDGKPAS(0.5)PT(0.5)PVIVASHTANKEEK;STAQQELDGKPAS(0.865)PT(0.135)PVIVASHTANKEEK ;; 122.78 6.82E-13 2149388000 8559.9 6950.4 7105.7 7740.6 6745.5 6639.2 5239.49 4795.83 9264.4 7764 TRUE FALSE FALSE 7882.374883 7551.161606 7369.043493 7708.571448 6665.064318 5262.155081 5386.495988 6258.05649 8248.118498 8033.798422 0.981151688 0.939924206 0.917255214 0.959517658 0.829628025 0.65500213 0.670479355 0.778966083 1.026677303 1 12.97186655 -5.589366844 2.410114042 0.979975734 0.698240822 0.888156296 0.042899036 0.062573501 0.731317578 0.00631722 0.014650178 2.57E-06 5.589366844 -0.281734911 STAQQELDGKPASPT(ph)PVIVASHTANK ddPTM_HeLa_Curcumin_4h_R1 1 STAQQELDGKPASPTPVIVASHTANK 26 1 H0YAC7;P35606-2;P35606 H0YAC7 COPB2 Coatomer subunit beta 1 0 S(0.001)T(0.001)AQQELDGKPAS(0.204)PT(0.767)PVIVAS(0.021)HT(0.006)ANK 50.055 0.0070369 9939200 2442.3 1972 1765.7 2164.2 2199.1 2289.5 1704.4 1546.2 2135 2141.1 TRUE FALSE FALSE 2248.989378 2142.450893 1831.138395 2155.245114 2172.877169 1814.631892 1752.220877 2017.629262 1900.795842 2215.503066 1.015114541 0.967026824 0.826511334 0.972801684 0.980760172 0.819060881 0.790890748 0.910686739 0.857952251 1 11.11341861 -6.058765332 0.516751085 1.011214194 0.830537215 0.048492965 0.077621979 0.71377153 0.338676343 0.016436669 0.057878957 8.73E-07 6.058765332 -0.180676979 STAYEDYYYHPPPR ddPTM_HeLa_Curcumin_4h_R1 3 STAYEDYYYHPPPR 14 0 O43390;B4DT28;O43390-4;O43390-3;O43390-2;A0A286YEZ8 O43390 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 0 ;; ;; 92.781 0.0041308 21965400 6587.9 5611 5936 6258.6 5967.5 7065.8 6065.8 4810.88 6830.7 5889.3 FALSE FALSE TRUE 6066.460763 6095.989838 6155.993382 6232.703572 5896.34146 5600.273432 6235.990023 6277.695165 6081.3893 6093.952737 0.995488647 1.000334282 1.01018069 1.02276861 0.967572562 0.918988655 1.023307907 1.030151601 0.997938376 1 12.5731626 -5.747453129 24.95483809 1.00060753 0.983025631 0.083648358 0.02966409 534.3346647 953375.3017 0.004376434 0.008721587 1.79E-06 5.747453129 -0.017581899 STCIYGGAPK ddPTM_HeLa_Curcumin_4h_R1 2 STCIYGGAPK 10 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2;P17844-2;P17844;J3KTA4;J3QRQ7;J3KRZ1 A0A1X7SBZ2;P17844-2 DDX17;DDX5 Probable ATP-dependent RNA helicase DDX17;Probable ATP-dependent RNA helicase DDX5 0 0 ; ; 149.82 5.46E-06 7025300 6596.8 5621.2 6497.1 5615.8 6063.9 8128.2 6680 5428.8 6658.8 6383.4 FALSE FALSE TRUE 6074.656319 6107.07148 6737.888241 5592.563308 5991.591953 6442.319696 6867.422822 7084.016129 5928.346299 6605.222675 0.919674721 0.924582225 1.02008495 0.84668808 0.907099162 0.975337247 1.039695883 1.072487103 0.897524064 1 12.68939148 -4.745683173 2.939110638 0.950544766 1.065567122 0.475409065 0.049586437 0.195654005 3.343318813 0.007350161 0.032649721 1.80E-05 4.745683173 0.115022356 STCS(ph)CPDLQPNGQDLGENSR ddPTM_HeLa_Curcumin_4h_R1 2 STCSCPDLQPNGQDLGENSR 20 0 O43847;O43847-2;F5H7V1 O43847 NRD1 Nardilysin 1 0 S(0.001)T(0.002)CS(0.997)CPDLQPNGQDLGENSR;S(0.171)T(0.048)CS(0.781)CPDLQPNGQDLGENSR ; 218.05 9.41E-19 16949700 2611.1 2627.31 2659.39 2011.17 2828.22 2788.16 2042.19 2617.24 2250.44 2287.34 TRUE FALSE FALSE 2404.42868 2854.402969 2757.949333 2002.848311 2794.495324 2209.864187 2099.488355 3415.224428 2003.572362 2366.824895 1.015887861 1.206005132 1.165252799 0.846217359 1.180693734 0.933683008 0.88704845 1.442956103 0.846523275 1 11.20873726 -4.249723191 24.43903011 1.021242251 1.442956451 0.500747189 0.129466634 755.5193878 1575913.247 0.015273615 0.326393463 5.63E-05 4.249723191 0.4217142 VFDVNRPCS(ph)PDSTTGSFADSFSSQK ddPTM_HeLa_Curcumin_4h_R1 1 VFDVNRPCSPDSTTGSFADSFSSQK 25 1 Q9NRE2-2;Q9NRE2 Q9NRE2-2 TSHZ2 Teashirt homolog 2 1 0 VFDVNRPCS(0.702)PDS(0.087)T(0.087)T(0.058)GS(0.02)FADS(0.028)FS(0.008)S(0.01)QK 45.679 0.016439 14333000 1730.6 1463.5 1255.4 1473.1 1514.9 1760.2 1196.3 431.1 1780.5 1296.2 TRUE FALSE FALSE 1593.621184 1589.998419 1301.926228 1467.004703 1496.835807 1395.114678 1229.864958 562.5404055 1585.183605 1341.242854 1.188167512 1.185466461 0.970686423 1.093765159 1.116006548 1.040165601 0.916959188 0.419417262 1.181876646 1 10.38935477 -4.133246017 1.648371641 1.090877312 0.010726452 0.891183297 0.071538673 0.373010119 0.749336178 0.011985397 0.703435283 7.36E-05 4.133246017 -1.08015086 down VYS(ph)PYNHR ddPTM_HeLa_Curcumin_4h_R1 2 VYSPYNHR 8 0 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 0 VY(0.002)S(0.947)PY(0.051)NHR;VY(0.002)S(0.988)PY(0.01)NHR ; 97.597 0.016459 59421000 6746.3 5909.5 5595.1 5659 6400.4 6871.2 4946.3 1730.36 5533.3 5616.7 TRUE FALSE FALSE 6212.323236 6420.290848 5802.459328 5635.584557 6324.07941 5446.035666 5085.079866 2257.938798 4926.310834 5811.879907 1.068900827 1.104684018 0.998379082 0.969666381 1.088129747 0.93705234 0.874945792 0.388504036 0.847627775 1 12.50478918 -4.130878846 1.550276004 1.033198388 1.18E-23 0.856668077 0.074669728 0.242508961 0.42060966 0.006916196 0.41638304 7.40E-05 4.130878846 -1.033198388 down STDSEVSQS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 6 STDSEVSQSPAK 12 0 A0A0G2JNJ7;H7C148;H7C3F5;A0A2H2FJL5;B7Z6J7;O75175 A0A0G2JNJ7 CNOT3 CCR4-NOT transcription complex subunit 3 1 0 STDS(0.006)EVS(0.008)QS(0.986)PAK;STDSEVSQS(1)PAK;STDSEVS(0.004)QS(0.996)PAK;STDS(0.021)EVS(0.024)QS(0.954)PAK;STDS(0.106)EVS(0.044)QS(0.85)PAK;STDSEVS(0.157)QS(0.843)PAK ;;;;; 233.52 2.79E-19 451393300 28532 23183.7 24863 25230.5 24598.5 28651.8 22561.2 11479.3 27472.8 24968.4 TRUE FALSE FALSE 26273.66209 25187.59572 25784.44465 25126.10288 24305.17895 22709.09371 23194.20655 14979.28573 24459.10257 25836.05004 1.01693804 0.974901182 0.998002582 0.972521064 0.940746705 0.878969257 0.897745844 0.579782347 0.946704412 1 14.6570979 -3.743067993 0.822309553 1.001490554 1.22E-27 0.899733019 0.038355194 0.860039446 0.235134435 0.00517057 0.958625072 0.000180689 3.743067993 -1.001490554 STDSSS(ph)VSGSLQQETK ddPTM_HeLa_Curcumin_4h_R1 2 STDSSSVSGSLQQETK 16 0 Q9H8G2;A0A3B3ISJ3 Q9H8G2 CAAP1 Caspase activity and apoptosis inhibitor 1 1 0 STDSS(0.04)S(0.959)VS(0.001)GSLQQETK;STDSS(0.049)S(0.951)VSGSLQQETK ; 213.69 9.67E-32 11660000 10865.5 9823.2 10124.2 10693.3 10286.7 11684.9 9929.1 9597.3 11301.9 11903 TRUE FALSE FALSE 10005.48421 10672.27364 10499.41176 10649.05396 10164.03782 9261.320024 10207.68382 12523.47259 10062.10985 12316.62836 0.812355777 0.866493112 0.852458274 0.864607882 0.825228912 0.751936305 0.828772577 1.0167939 0.816953272 1 13.58831976 -9.346175656 0.934576307 1.005438456 0.845697075 0 0.084946171 0.449758358 0.664461699 0.050998475 0.011670287 4.51E-10 9.346175656 -0.159741381 STELKTEIKEEEDQPSTSATQS(ph)SPAPGQSK ddPTM_HeLa_Curcumin_4h_R1 2 STELKTEIKEEEDQPSTSATQSSPAPGQSK 30 2 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 0 STELKTEIKEEEDQPSTS(0.003)AT(0.017)QS(0.489)S(0.489)PAPGQSK;STELKTEIKEEEDQPS(0.024)T(0.08)S(0.102)AT(0.102)QS(0.346)S(0.346)PAPGQSK ; 97.771 1.38E-08 49012000 7870.4 6048.3 5479.3 6646.6 4843.9 7735.4 5426.3 3828.8 8704.2 6793.3 TRUE FALSE FALSE 7247.449535 6571.088101 5682.367678 6619.09813 4786.139656 6130.990844 5578.547374 4996.183494 7749.371037 7029.366669 1.03102454 0.934805141 0.808375483 0.941635064 0.680877792 0.872196761 0.793605973 0.710758697 1.102428057 1 12.779179 -6.702702727 1.114119593 1.016923572 0.784310002 0.684761526 0.07403181 0.181913354 0.451829231 0.01206654 0.019045111 1.98E-07 6.702702727 -0.232613569 STESLQANVQR ddPTM_HeLa_Curcumin_4h_R1 2 STESLQANVQR 11 0 P26373;J3QSB4 P26373 RPL13 60S ribosomal protein L13 0 0 ; ; 201.61 1.63E-18 14088000 3465.8 2876.1 2955.4 3240.9 2901.6 4100.5 2790.4 6730.2 2966.6 3010.8 FALSE FALSE TRUE 3191.478273 3124.697268 3064.929724 3227.490015 2867.000315 3250.010078 2868.691114 8782.206998 2641.171402 3115.425076 1.02441182 1.002976221 0.983791826 1.035970995 0.920259754 1.043199563 0.920802473 2.818943414 0.847772403 1 11.60521331 -4.259876785 24.99999978 1.002443546 2.818944012 0.986755653 0.064003571 5.948783856 95165.80469 0.005065037 0.042976252 5.50E-05 4.259876785 1.816500466 STETSDFENIES(ph)PLNER ddPTM_HeLa_Curcumin_4h_R1 2 STETSDFENIESPLNER 17 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 1 0 STETSDFENIES(1)PLNER;STETSDFENIES(1)PLNER ; 241.11 2.07E-30 63704700 6318.9 5815.4 6087.1 6316.9 7042.4 7744.1 6276.7 7309 5922.6 5443.6 TRUE FALSE FALSE 5818.752397 6318.057263 6312.693281 6290.762342 6958.42398 6137.886366 6452.807309 9537.480454 5272.905598 5632.764695 1.033018901 1.121661849 1.120709567 1.116816108 1.23534789 1.089675621 1.14558439 1.693214784 0.936113238 1 12.45962749 -1.457025403 0.982421615 1.048813242 200 0.828505732 0.081856626 152.8421511 0.60165489 0.012835648 67907.66694 0.034911989 1.457025403 198.9511868 STFAGS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 STFAGSPER 9 0 H0YE03;H7C3G7;Q2TBE0-3;Q2TBE0-2;Q2TBE0 H0YE03 CWF19L2 CWF19-like protein 2 1 0 ST(0.001)FAGS(0.999)PER 93.561 0.016905 21312000 3091.2 3151.6 3695 3251.9 3750 3639.8 2939.7 1708.7 3039.9 2765.1 TRUE FALSE FALSE 2846.528258 3424.010261 3831.93995 3238.444499 3705.283699 2884.864451 3022.18007 2229.674764 2706.430575 2861.187019 0.994876685 1.1967097 1.339283285 1.131853485 1.295016255 1.008275388 1.056267923 0.779283126 0.945911804 1 11.48239809 -3.06052996 9.502776273 1.052425842 1.074606648 0 0.161938404 0 0 0.022039555 0 0.000869901 3.06052996 0.022180807 STFREESPLR ddPTM_HeLa_Curcumin_4h_R1 2 STFREESPLR 10 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 0 ; ; 118.03 0.0016816 0 8342.8 7109.9 7154.6 6963.9 7601.3 8795.7 8200.2 6002.9 8460.8 7534.8 FALSE FALSE TRUE 7682.458577 7724.448075 7419.75577 6935.085227 7510.659462 6971.372672 8430.275542 7833.156576 7532.671408 7796.633739 0.985355839 0.990741432 0.95166145 0.889497373 0.963320801 0.894151618 1.081271203 1.004684437 0.966144064 1 12.92863565 -6.805212277 9.717322334 0.992737545 0.962827116 0.032119445 0.051785904 0.852870599 182.1239867 0.00842104 0.011092976 1.57E-07 6.805212277 -0.029910429 STFS(ph)TNYR ddPTM_HeLa_Curcumin_4h_R1 1 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 STFS(0.5)T(0.5)NYR 122.94 0.0073567 73786000 2218.3 1466 1780.2 1879.9 1834.8 2734.4 1942.8 1051.6 2175.3 1598.2 TRUE FALSE FALSE 2042.719214 1592.714508 1846.175778 1872.121472 1812.921208 2167.254617 1997.309739 1372.227999 1936.675032 1653.737331 1.235213825 0.963100051 1.116365788 1.132054914 1.09625705 1.310519256 1.207755126 0.829773854 1.171089868 1 10.69151439 -6.526517756 24.85088018 1.100062273 1.129601654 9.61E-05 0.134883544 631.8638797 4315002.248 0.022754481 0.032272139 2.97E-07 6.526517756 0.02953938 STFSTNYR ddPTM_HeLa_Curcumin_4h_R1 2 STFSTNYR 8 0 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 0 0 ; ; 183.26 1.03E-14 21740300 4093.8 2494.09 3583.9 3284.3 3974.1 4742.3 3304.5 2409.46 3370.9 3363.9 FALSE FALSE TRUE 3769.77141 2709.668026 3716.722487 3270.710437 3926.711453 3758.693523 3397.215376 3144.093262 3001.120704 3480.795275 1.083020147 0.778462338 1.067779686 0.939644587 1.128107557 1.079837574 0.975988275 0.903268654 0.862193972 1 11.76520125 ALSSSK(ac)QSSSSR ddPTM_HeLa_Curcumin_4h_R1 2 ALSSSKQSSSSR 12 1 P53999;D6RC37;D6R970 P53999 SUB1 Activated RNA polymerase II transcriptional coactivator p15 0 1 ; ALSSSK(1)QSSSSR;ALSSSK(1)QSSSSR 307.97 6.10E-134 19019100 1058.03 1157.85 1476.11 1155.51 1486.13 2052.05 2076.5 2130.71 1203.32 1027.18 FALSE TRUE FALSE 974.2858091 1257.929395 1530.815935 1150.728806 1468.40887 1626.431699 2134.761001 2780.35367 1071.318807 1062.874429 0.916651848 1.183516473 1.440260386 1.082657344 1.381545017 1.530219991 2.00847903 2.615881609 1.00794485 1 10.05375545 -1 0.406706068 0.963440924 29.95757079 0.93802165 0.125953359 10.26143755 0.119938011 0.031731901 242.2258991 0.1 1 28.99412987 up STFVQSPADACT(ph)PPDTSSASEDEGSLRR ddPTM_HeLa_Curcumin_4h_R1 1 STFVQSPADACTPPDTSSASEDEGSLRR 28 1 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 1 0 STFVQS(0.012)PADACT(0.988)PPDTSSASEDEGSLRR 107.75 1.02E-09 8409400 423.96 449.03 516.32 609.28 331.77 522.47 311.18 241.66 461.87 432.75 TRUE FALSE FALSE 390.4031186 487.8421524 535.4552734 606.7589608 327.8138594 414.1038325 319.9108733 315.3410215 411.2040165 447.7880303 0.871848045 1.089448845 1.195778442 1.355013801 0.732073743 0.924776467 0.714424798 0.704219408 0.918300599 1 8.806672154 STFVQSPADACTPPDTS(ph)S(ph)ASEDEGSLRR ddPTM_HeLa_Curcumin_4h_R1 1 STFVQSPADACTPPDTSSASEDEGSLRR 28 1 Q9P265 Q9P265 DIP2B Disco-interacting protein 2 homolog B 2 0 S(0.001)T(0.001)FVQS(0.001)PADACT(0.012)PPDT(0.401)S(0.68)S(0.68)AS(0.203)EDEGS(0.022)LRR 53.777 0.0043561 0 1022.2 1003 959.31 1034.1 948.97 1140.1 856.96 945.07 1110.4 910.2 TRUE FALSE FALSE 941.2917914 1089.694851 994.8628725 1029.821168 937.6541525 903.6304084 881.0039912 1233.217492 988.5918981 941.8293823 0.999429206 1.156998148 1.056309021 1.093426461 0.995566894 0.959441726 0.935417824 1.309385241 1.049650729 1 9.879321921 -4.251916251 24.88321682 1.014049136 1.309385408 0.638034609 0.063012797 578.6823373 1512020.763 0.008933999 0.152506182 5.60E-05 4.251916251 0.295336272 STGCDFAVSPK ddPTM_HeLa_Curcumin_4h_R1 1 STGCDFAVSPK 11 0 P55809;E9PDW2;P55809-2 P55809 OXCT1 "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial" 0 0 124.67 0.0014933 1869700 1840.9 1508.2 1668.6 1752.9 2148.1 2557.3 1512.5 1375.1 2082.1 1587.4 FALSE FALSE TRUE 1695.190822 1638.562088 1730.439784 1745.646964 2122.48531 2026.887153 1554.936679 1794.36166 1853.698839 1642.562032 1.032040672 0.997564814 1.053500416 1.062758624 1.292179698 1.233979061 0.946653246 1.092416375 1.128541147 1 10.68173214 -5.990486948 24.93612604 1.018342419 1.13945349 0.183933524 0.092725639 197.7375679 518316.5115 0.013105243 0.02373203 1.02E-06 5.990486948 0.121111071 STGDGTLGR ddPTM_HeLa_Curcumin_4h_R1 2 STGDGTLGR 9 0 Q32MZ4-2;Q32MZ4;Q32MZ4-3 Q32MZ4-2 LRRFIP1 Leucine-rich repeat flightless-interacting protein 1 0 0 ; ; 100.02 0.0097238 766410 1101.57 1313.67 992.68 952.13 931.94 1292.97 874.98 865.36 884.41 968.7 FALSE FALSE TRUE 1014.379572 1427.217781 1029.469594 948.1903383 920.8272242 1024.793447 899.5295839 1129.20428 787.3924357 1002.362253 1.011988998 1.423854277 1.027043458 0.945955752 0.918657124 1.022378331 0.897409675 1.126543101 0.785536799 1 9.969188276 -6.506178941 24.9305812 1.046149091 0.977213804 0.044397018 0.15779428 1891.192174 2823300.162 0.021651193 0.032567759 3.12E-07 6.506178941 -0.068935287 STGEAFVQFASK ddPTM_HeLa_Curcumin_4h_R1 1 STGEAFVQFASK 12 0 P31942;P31942-3;P31942-2 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 0 113.24 0.0023065 1148100 730.88 746.75 818.2 889.36 668.81 1056.2 959.89 746.66 918.64 772.08 FALSE FALSE TRUE 673.0300768 811.2957425 848.5232118 885.680064 660.8348776 837.1322142 986.82193 974.3131968 817.8674903 798.9097225 0.842435707 1.015503654 1.062101496 1.108610947 0.827170904 1.047843318 1.235210816 1.219553561 1.023729549 1 9.641888676 -4.891635206 3.754271474 0.949345657 1.22808107 0.519614842 0.088316339 0.122490888 3.244758981 0.013892637 0.047027285 1.28E-05 4.891635206 0.278735413 STGGAPTFNVT(ph)VTK ddPTM_HeLa_Curcumin_4h_R1 2 STGGAPTFNVTVTK 14 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 1 0 STGGAPTFNVT(0.999)VTK;STGGAPTFNVT(0.983)VT(0.017)K ; 150.01 0.001485 60553000 3040.3 2106.88 3076.1 3307.4 2795.9 3991.3 2656.1 2478.2 3229.6 2500.8 TRUE FALSE FALSE 2799.657047 2288.989319 3190.102972 3293.714855 2762.560719 3163.459389 2730.623017 3233.791772 2875.32096 2587.702614 1.081908343 0.884564288 1.232793504 1.272833608 1.06757272 1.222497273 1.055230614 1.249676742 1.111148145 1 11.33745611 -6.737704462 24.99963752 1.02820104 1.178179447 0.452484185 0.088068096 162.2511749 170896.3271 0.012833796 0.01814404 1.83E-07 6.737704462 0.149978408 STGGAPTFNVTVTK ddPTM_HeLa_Curcumin_4h_R1 2 STGGAPTFNVTVTK 14 0 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 0 ; ; 223.36 1.57E-27 103496000 6026 4512.1 5038.4 4959.5 5014.6 6911.8 5775.9 5512.5 5186.5 4590.4 FALSE FALSE TRUE 5549.035741 4902.105818 5225.127536 4938.978903 4954.80417 5478.214768 5937.956209 7193.235874 4617.553926 4749.916058 1.168238696 1.032040516 1.10004629 1.039803408 1.043135102 1.153328754 1.250118136 1.514392209 0.972133795 1 12.2136863 -4.246427404 1.350608201 1.074089176 1.714053371 0.865909088 0.055789527 0.414439101 0.632459495 0.00948044 0.365322484 5.67E-05 4.246427404 0.639964194 STGHTPTKPS(ph)GSSVSEK ddPTM_HeLa_Curcumin_4h_R1 1 STGHTPTKPSGSSVSEK 17 1 Q8NI08-2;Q8NI08;Q8NI08-7 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 0 STGHT(0.349)PT(0.191)KPS(0.381)GS(0.019)S(0.024)VS(0.035)EK 63.546 0.012482 18641000 3949.6 3621.3 3613.4 3365.6 5452.2 8044.2 4921.8 2511.8 5259.9 3860.8 TRUE FALSE FALSE 3636.984992 3934.309036 3747.315783 3351.674039 5387.186076 6375.742243 5059.892462 3277.636257 4682.90213 3994.962513 0.910392771 0.98481751 0.938010249 0.838975091 1.348494775 1.59594545 1.266568196 0.820442306 1.17220177 1 11.96396625 -5.756704539 24.99991801 0.949902208 1.282633314 0.328162396 0.195840284 86.17563514 455001.0463 0.026459359 0.05157285 1.75E-06 5.756704539 0.332731105 FWEVISDEHGIDPTGTYHGDS(ph)DLQLER ddPTM_HeLa_Curcumin_4h_R1 1 FWEVISDEHGIDPTGTYHGDSDLQLER 27 0 P04350;M0QYM7;M0R0X0;M0QY85;M0QY37;M0QX14;M0R2D3;M0QZL7;M0R278;P68371 P04350;P68371 TUBB4A;TUBB4B Tubulin beta-4A chain;Tubulin beta-4B chain 1 0 FWEVISDEHGIDPT(0.033)GT(0.064)Y(0.057)HGDS(0.845)DLQLER 45.679 0.011782 3212300 1134.7 824.02 928.24 774.93 922.2 1973 1284.5 1901.8 1335.9 1129.1 TRUE FALSE FALSE 1044.887298 895.244617 962.641391 771.723545 911.2033673 1563.77756 1320.539613 2481.650065 1189.355112 1168.336141 0.894337906 0.766256033 0.823942149 0.660532117 0.779915416 1.338465451 1.1302737 2.124089103 1.017990517 1 10.1902397 -3.175953802 0.993697038 0.901439997 10.12931419 0.840123645 0.161291633 3.955956585 0.574349674 0.025128197 64.48952382 0.000666878 3.175953802 9.227874189 up STGSAT(ph)SLASQGER ddPTM_HeLa_Curcumin_4h_R1 1 STGSATSLASQGER 14 0 H0Y2V6;Q5SW79;Q5SW79-3;Q5SW79-2 H0Y2V6 CEP170 Centrosomal protein of 170 kDa 1 0 S(0.002)T(0.001)GS(0.259)AT(0.736)S(0.001)LASQGER 186.29 3.29E-21 0 663.26 761.01 697.79 617.17 610.94 914.32 848.29 363.13 936.24 812.28 TRUE FALSE FALSE 610.7622711 826.7883134 723.6507112 614.6163141 603.6549395 724.6797255 872.0907343 473.8466654 833.5368144 840.5066695 0.726659637 0.983678468 0.860969624 0.731245017 0.718203628 0.862193903 1.037577411 0.563763124 0.991707555 1 9.715115457 -9.511323787 1.198524442 1.002430921 0.810837873 0.244317553 0.130239905 0.579146725 1.458129176 0.093488244 0.021382075 3.08E-10 9.511323787 -0.191593049 STGTEPPGEVRLADS(ph)AASR ddPTM_HeLa_Curcumin_4h_R1 1 STGTEPPGEVRLADSAASR 19 1 O43586-2 O43586-2 1 0 STGTEPPGEVRLADS(1)AASR 112.12 0.0039691 21861000 2934 2252.6 2571.9 2197.8 2409.6 2753.3 1903.4 1504.5 2462.3 2372.2 TRUE FALSE FALSE 2701.770804 2447.304707 2667.216876 2188.706086 2380.867094 2182.234544 1956.804281 1963.215124 2192.19185 2454.633773 1.100681834 0.997014191 1.086604815 0.891662988 0.96994799 0.889026529 0.797187875 0.799799606 0.893083064 1 11.26129208 -5.314267484 0.783363183 1.047203112 0.76826714 0.545938484 0.068115944 0.328202718 0.306318888 0.009266453 0.058673297 4.85E-06 5.314267484 -0.278935971 YLLSQS(ph)SPAPLTAAEEELR ddPTM_HeLa_Curcumin_4h_R1 1 YLLSQSSPAPLTAAEEELR 19 0 F8VS81;Q12792-4;Q12792;Q12792-3 F8VS81 TWF1 Twinfilin-1 1 0 YLLSQS(0.677)S(0.322)PAPLTAAEEELR 157.74 2.66E-05 30902000 1556.9 1133.7 1332 1607 1270.1 2705.1 2387.7 5446.7 1386.3 1151.6 TRUE FALSE FALSE 1433.669722 1231.691976 1381.365092 1600.35066 1254.954887 2144.031767 2454.692436 7107.373756 1234.226358 1191.618014 1.203128607 1.033629873 1.159234818 1.343006434 1.053151993 1.799260956 2.059965867 5.964473238 1.035756714 1 10.21870612 -3.13023274 1.102518011 1.111431434 50.52587679 0.981828943 0.194145481 1.409509919 0.193190671 0.028049379 143.2199212 0.000740913 3.13023274 49.41444535 up STIGVMVTAS(ph)HNPEEDNGVK ddPTM_HeLa_Curcumin_4h_R1 6 STIGVMVTASHNPEEDNGVK 20 0 D6RC77;D6RCQ8;D6RF77;A0A494C163;A0A494C099;A0A494C0G1;H0Y987;O95394;O95394-3;O95394-4 D6RC77 PGM3 Phosphoacetylglucosamine mutase 1 0 STIGVMVT(0.025)AS(0.975)HNPEEDNGVK;STIGVMVT(0.001)AS(0.999)HNPEEDNGVK;STIGVMVTAS(1)HNPEEDNGVK;STIGVMVT(0.009)AS(0.991)HNPEEDNGVK;STIGVMVT(0.015)AS(0.985)HNPEEDNGVK;STIGVMVT(0.029)AS(0.971)HNPEEDNGVK ;;;;; 135.86 6.62E-05 555529900 31085.6 24828.3 28176.8 27117.8 29197.2 34616 26471.5 22296.5 30753.2 26584.9 TRUE FALSE FALSE 28625.14196 26974.34762 29221.05699 27005.59373 28849.04246 27436.2514 27214.21905 29094.60021 27379.6509 27508.7233 1.040584169 0.980574319 1.062246935 0.981710181 1.048723423 0.997365494 0.989294151 1.057649964 0.995307947 1 14.74760156 -4.23090696 22.30372901 1.016347983 1.057650257 0.174469277 0.028326654 3468.154765 2533280.944 0.00360452 0.445143485 5.88E-05 4.23090696 0.041302274 GAPS(ph)SPATGVLPS(ph)PQGK ddPTM_HeLa_Curcumin_4h_R1 1 GAPSSPATGVLPSPQGK 17 0 Q5SRE5-2;Q5SRE5 Q5SRE5-2 NUP188 Nucleoporin NUP188 homolog 2 0 GAPS(0.969)S(0.031)PATGVLPS(1)PQGK 208.62 1.43E-10 24632000 2435.3 2282.3 2085.3 2342.5 2074.9 3527.5 3367 4743.4 2878.4 1778.9 TRUE FALSE FALSE 2242.543435 2479.571842 2162.583052 2332.807356 2050.158173 2795.856737 3461.468958 6189.640824 2562.646721 1840.716643 1.218299103 1.347068737 1.174859293 1.267336483 1.113782603 1.518895778 1.880500713 3.362625556 1.39220055 1 10.84605184 -3.090469107 0.877032111 1.131442591 17.50196235 0.958182451 0.133787681 1.683865168 0.198166497 0.019752842 42.68471725 0.000811953 3.090469107 16.37051976 up STLEPVEK ddPTM_HeLa_Curcumin_4h_R1 2 STLEPVEK 8 0 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;P17066;P48741 A0A0G2JIW1;P17066 HSPA1B;HSPA1A;HSPA6;HSPA7 Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 0 ; ; 155.1 8.59E-06 35336000 12059.8 10168.4 10253.9 11191.2 10922.3 13460.6 10458.2 10000.6 11998.7 9522.8 FALSE FALSE TRUE 11105.2541 11047.31119 10633.91855 11144.89378 10792.05871 10668.71983 10751.62895 13049.7369 10682.47263 9853.716591 1.127011722 1.121131411 1.079178446 1.131034537 1.095227228 1.082710237 1.091124232 1.324346685 1.084105934 1 13.26645226 -13.52287875 0.120172203 0.578958597 1.196854766 0.262335944 0.06747016 71.22821439 0.618003827 7.357440449 0.296935108 3.00E-14 13.52287875 0.61789617 STLESEKPGSPEAAET(ph)S(ph)PPSNIIDHCEK ddPTM_HeLa_Curcumin_4h_R1 1 STLESEKPGSPEAAETSPPSNIIDHCEK 28 1 Q96T23-3;Q96T23-2;Q96T23;H0YER1;H0YCN2 Q96T23-3 RSF1 Remodeling and spacing factor 1 2 0 S(0.013)T(0.014)LES(0.017)EKPGS(0.071)PEAAET(0.929)S(0.94)PPS(0.016)NIIDHCEK 59.282 0.0012163 117350000 5262.2 3777.6 4728.8 4654.4 4640.3 5817.7 4275.7 4255.5 5186.5 4750.9 TRUE FALSE FALSE 4845.691317 4104.118911 4904.053488 4635.141326 4584.967453 4611.043441 4395.664635 5552.98236 4617.553926 4915.993421 0.985699309 0.834850367 0.997571206 0.942869717 0.932663464 0.937967781 0.894155923 1.129574815 0.939292129 1 12.26326727 -7.495490298 24.73383204 0.993690918 0.947669205 0 0.073832906 498.3284398 450033.3882 0.01152111 0.012466133 3.20E-08 7.495490298 -0.046021713 STLNEIYFGK ddPTM_HeLa_Curcumin_4h_R1 2 STLNEIYFGK 10 0 B1AK87;P47756-2;P47756;B1AK88 B1AK87 CAPZB F-actin-capping protein subunit beta 0 0 ; ; 190.96 3.79E-20 7282100 3446.4 2758.9 3312.1 3050.6 3172.6 3813.6 3627.1 3421.7 3575.2 3198 FALSE FALSE TRUE 3173.613803 2997.367023 3434.84934 3037.977426 3134.768817 3022.616372 3728.866664 4464.960578 3183.009505 3309.130262 0.959047711 0.905786955 1.037991577 0.918059183 0.947308981 0.913417162 1.12684191 1.349285228 0.961887038 1 11.69223637 -4.423370453 2.732742752 0.96876288 1.36461868 0.89381081 0.042123173 0.076207904 0.91134868 0.005964422 0.056280209 3.77E-05 4.423370453 0.3958558 STLNEIYFGK(ac)TK ddPTM_HeLa_Curcumin_4h_R1 1 STLNEIYFGKTK 12 1 B1AK87;P47756-2;P47756;B1AK88 B1AK87 CAPZB F-actin-capping protein subunit beta 0 1 STLNEIYFGK(1)TK 148.62 5.90E-05 1348700 459.95 508.29 447.9 477.04 586.19 760.49 543.71 389.06 588.46 540.54 FALSE TRUE FALSE 423.5444722 552.2243227 464.499568 475.0661349 579.2000671 602.7558015 558.9650393 507.682603 523.9074103 559.3237248 0.757243888 0.987307168 0.830466414 0.849358098 1.035536383 1.077651054 0.999358716 0.907672213 0.936680114 1 9.127539716 -5.758857963 24.99878871 0.884365802 1.009833218 0.317893046 0.079247813 73.26530438 709496.2542 0.014927371 0.02878958 1.74E-06 5.758857963 0.125467416 STLNPQWNES(ph)FTFK ddPTM_HeLa_Curcumin_4h_R1 2 STLNPQWNESFTFK 14 0 P17252;J3KRN5 P17252 PRKCA Protein kinase C alpha type 1 0 STLNPQWNES(0.983)FT(0.017)FK;STLNPQWNES(0.996)FT(0.004)FK ; 222.45 2.33E-14 210484000 7840.4 5393.9 7227.9 6845.2 6668.5 9118.7 6390.3 7879.2 7962.7 6844 TRUE FALSE FALSE 7219.824067 5860.124681 7495.772332 6816.876376 6588.982493 7227.378831 6569.594619 10281.53181 7089.211732 7081.828491 1.019485868 0.827487518 1.058451549 0.962587047 0.930406957 1.02055265 0.927669263 1.45181881 1.001042561 1 12.78990619 -4.25681979 24.99874228 0.988861603 1.451818996 0.833272572 0.063992794 136.5032703 738656.6896 0.00837268 0.090088861 5.54E-05 4.25681979 0.462957393 STLPDADRER ddPTM_HeLa_Curcumin_4h_R1 2 STLPDADRER 10 1 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 0 ; ; 140.11 3.56E-05 22245000 9571.6 5972 8183.8 7442.3 9487.8 10457.3 8619.3 8087.9 7020.9 7019.7 FALSE FALSE TRUE 8813.99776 6488.193069 8487.098827 7411.505735 9374.664182 8288.338102 8861.13436 10553.86348 6250.724835 7263.634052 1.21344188 0.893243385 1.168437006 1.02035781 1.290630023 1.141073193 1.219931276 1.452972906 0.860550627 1 12.82647581 -1 0.53520383 1.08690053 15.15825294 0.486979526 0.124921605 73.82138732 0.643978617 0.020850039 1192.788743 0.1 1 14.07135241 STLS(ph)PPEASPGPPAAPR ddPTM_HeLa_Curcumin_4h_R1 2 STLSPPEASPGPPAAPR 17 0 Q6NUJ5-2;Q6NUJ5 Q6NUJ5-2 PWWP2B PWWP domain-containing protein 2B 1 0 S(0.032)T(0.01)LS(0.954)PPEAS(0.004)PGPPAAPR;S(0.015)T(0.015)LS(0.97)PPEAS(0.001)PGPPAAPR ; 116.87 0.00077501 17702200 4302.7 3848.8 4076.74 4032.2 4485.3 5091.9 3596.3 2026.23 4529.7 4215.6 TRUE FALSE FALSE 3962.136755 4181.473122 4227.827571 4015.515825 4431.815727 4035.782542 3697.202499 2644.018199 4032.803243 4362.091786 0.908311184 0.958593566 0.969220222 0.920548219 1.015984061 0.92519432 0.847575585 0.606135388 0.924511322 1 12.09080441 -4.236152387 1.728810594 0.957733428 0.469904403 0.912041055 0.032748768 0.233211495 0.643165215 0.005570257 0.190650532 5.81E-05 4.236152387 -0.487829025 STLTDSLVCK ddPTM_HeLa_Curcumin_4h_R1 2 STLTDSLVCK 10 0 P13639 P13639 EEF2 Elongation factor 2 0 0 ; ; 200.86 2.83E-21 18768400 11479.8 10152.9 11294.8 12392.9 10685 9782.7 8105 6501.7 11581.9 12311.7 FALSE FALSE TRUE 10571.16172 11030.47144 11713.39522 12341.62146 10557.58835 7753.657746 8332.404487 8484.0384 10311.39455 12739.53066 0.829792086 0.865845982 0.91945265 0.968765788 0.828726633 0.60862978 0.654058985 0.665961614 0.809401447 1 13.63702451 -5.417527118 3.743465974 0.91605989 0.644894495 0.791574235 0.058198356 0.086305438 2.176692821 0.010022438 0.023427253 3.82E-06 5.417527118 -0.271165395 STLTTLPFPGAEANS(ph)PGKAEAEKPR ddPTM_HeLa_Curcumin_4h_R1 2 STLTTLPFPGAEANSPGKAEAEKPR 25 2 Q96GV9 Q96GV9 C5orf30 UNC119-binding protein C5orf30 1 0 STLTTLPFPGAEANS(1)PGKAEAEKPR;STLT(0.001)T(0.001)LPFPGAEANS(0.998)PGKAEAEKPR ; 55.691 0.0022507 227096000 7176.8 5970 6065.5 7101.7 6143.2 7962.8 4790.1 2694.32 7535.1 6390.7 TRUE FALSE FALSE 6608.748707 6486.020198 6290.292766 7072.315047 6069.946352 6311.225521 4924.497314 3515.805765 6708.518382 6612.776349 0.99939093 0.980831629 0.951233254 1.069492551 0.917911938 0.954398756 0.74469437 0.531668633 1.014478341 1 12.69104039 -4.380615862 1.316636663 0.996918023 0.384147651 0.940382239 0.037129933 0.151805204 0.26372229 0.004778697 0.116815294 4.16E-05 4.380615862 -0.612770373 STNGDTFLGGEDFDQALLR ddPTM_HeLa_Curcumin_4h_R1 2 STNGDTFLGGEDFDQALLR 19 0 P38646 P38646 HSPA9 "Stress-70 protein, mitochondrial" 0 0 ; ; 222.75 5.96E-18 16521000 2806.1 2351.7 2613.5 2906.8 2972.7 4547.6 3116.8 2997.8 3551.6 2401.6 FALSE FALSE TRUE 2583.994224 2554.970469 2710.358609 2894.772432 2937.252494 3604.376498 3204.24902 3911.81542 3161.998366 2485.055421 1.03981352 1.028134201 1.090663245 1.164872384 1.181966595 1.450420971 1.289407468 1.574136088 1.272405572 1 11.27906231 -4.960892919 0.524019033 1.008449117 1.661957298 0.662205563 0.104582712 0.459057599 0.1316988 0.01223152 0.160212031 1.09E-05 4.960892919 0.653508182 STNT(ph)SQTGLVGTK ddPTM_HeLa_Curcumin_4h_R1 3 STNTSQTGLVGTK 13 0 Q96R06 Q96R06 SPAG5 Sperm-associated antigen 5 1 0 S(0.003)T(0.013)NT(0.88)S(0.1)QT(0.004)GLVGTK;STNT(0.988)S(0.011)QTGLVGTK;S(0.003)T(0.003)NT(0.985)S(0.009)QTGLVGTK ;; 180.95 1.76E-13 13260000 8332 6747.4 7156.9 7393.3 7501.5 12276 8064.3 2454.99 7593.9 6993.1 TRUE FALSE FALSE 7672.513408 7330.61519 7422.14101 7362.708484 7412.049512 9729.819221 8290.562554 3203.50515 6760.868169 7236.109704 1.060309161 1.013060262 1.025708746 1.01749542 1.024314143 1.344620192 1.14572096 0.44271097 0.934323614 1 12.82099857 -4.256164135 24.98065936 1.053725383 0.442710711 0.75037927 0.107184776 209.2896685 991049.1622 0.014602735 0.165308241 5.54E-05 4.256164135 -0.611014672 STPAEDDS(ph)PGDSQVK ddPTM_HeLa_Curcumin_4h_R1 2 STPAEDDSPGDSQVK 15 0 Q9UHB6-4;Q9UHB6-5 Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 STPAEDDS(1)PGDSQVK;STPAEDDS(1)PGDSQVK ; 203.52 2.05E-09 41183000 7658.1 6955.9 8385.8 7711.3 8059.1 9129.3 8032.7 8896.9 7652.9 6638.5 TRUE FALSE FALSE 7051.953304 7557.137001 8696.585125 7679.392684 7963.000496 7235.780272 8258.075943 11609.52385 6813.396017 6869.187381 1.026606629 1.100150073 1.266028228 1.117947766 1.159234718 1.053367723 1.202191101 1.690086936 0.991878026 1 12.74592372 -1.43292035 0.970242841 1.049964155 199.9999993 0.810429771 0.08514079 169.6630861 0.6627065 0.014764091 74432.29443 0.036904528 1.43292035 198.9500352 STPAEDDSRDSQVK ddPTM_HeLa_Curcumin_4h_R1 2 STPAEDDSRDSQVK 14 1 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;F8VRN8 Q9UHB6 LIMA1 LIM domain and actin-binding protein 1 0 0 ; ; 94.551 0.0060815 2329200 1043.32 1135.8 848.63 1021.22 951.62 1548.22 1096.01 1273.24 1464.95 1099.92 FALSE FALSE TRUE 960.7401211 1233.973491 880.0809743 1016.994462 940.272553 1227.10172 1126.761091 1661.445015 1304.24865 1138.142138 0.844130174 1.084199811 0.773261041 0.893556638 0.826146859 1.078162102 0.990000329 1.459786927 1.145945314 1 10.15246503 -3.127561534 1.146496764 0.920035766 6.877334966 0.60568637 0.11953354 7.083908964 0.968489911 0.014483913 91.4042772 0.000745484 3.127561534 5.9572992 STPENHPET(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 STPENHPETPK 11 0 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 1 0 STPENHPET(1)PK 90.759 0.015895 69600000 7047.5 6740.5 5989.3 6357.6 8889.6 9768.8 7736.7 3517.8 7872.2 5530.4 TRUE FALSE FALSE 6489.682939 7323.118785 6211.268727 6331.293936 8783.597326 7742.640763 7953.77098 4590.361026 7008.639355 5722.580988 1.134048247 1.279688099 1.085396387 1.106370351 1.534901357 1.352998023 1.389892252 0.802148722 1.224733974 1 12.48245026 -7.85772208 0.565224742 1.009661798 1.254385989 0 0.200881722 0.893642499 0.670772932 0.084007908 0.060734958 1.39E-08 7.85772208 0.244724191 STPES(ph)GDSDKESVGSSSTSNEGGR ddPTM_HeLa_Curcumin_4h_R1 3 STPESGDSDKESVGSSSTSNEGGR 24 1 Q6GQQ9-2;Q6GQQ9 Q6GQQ9-2 OTUD7B OTU domain-containing protein 7B 1 0 S(0.009)T(0.009)PES(0.681)GDS(0.212)DKES(0.031)VGS(0.006)S(0.018)S(0.025)T(0.007)S(0.002)NEGGR;S(0.003)T(0.003)PES(0.519)GDS(0.468)DKES(0.004)VGSS(0.001)S(0.001)TSNEGGR;S(0.078)T(0.078)PES(0.66)GDS(0.107)DKES(0.037)VGS(0.003)S(0.014)S(0.017)T(0.004)S(0.001)NEGGR ;; 66.31 0.00059334 91368400 6738.7 5551 5646.1 5877.6 5757.8 6633.1 5508.7 6210.49 6356.1 5658.7 TRUE FALSE FALSE 6205.324784 6030.803705 5855.349433 5853.280049 5689.141996 5257.32029 5663.259296 8104.039811 5658.851732 5855.339404 1.059772006 1.029966547 1.000001713 0.999648294 0.971616093 0.897867728 0.967195735 1.384042709 0.966442992 1 12.51553708 -4.257488989 24.98393341 1.009564745 1.384042856 0.868214319 0.045595202 118.6256301 750207.7427 0.007243063 0.073454381 5.53E-05 4.257488989 0.374478111 STPESGDS(ph)DKESVGSSSTSNEGGR ddPTM_HeLa_Curcumin_4h_R1 1 STPESGDSDKESVGSSSTSNEGGR 24 1 Q6GQQ9-2;Q6GQQ9 Q6GQQ9-2 OTUD7B OTU domain-containing protein 7B 1 0 S(0.002)T(0.002)PES(0.056)GDS(0.907)DKES(0.005)VGS(0.001)S(0.001)S(0.012)T(0.012)SNEGGR 79.935 0.00011221 82310000 1964.1 1730.8 1888.7 1663.7 1676.3 1535.5 1455.5 1559.7 2102.4 1575.8 TRUE FALSE FALSE 1808.639412 1880.40264 1958.696883 1656.81605 1656.311217 1217.019991 1496.337413 2035.24535 1871.77198 1630.558933 1.109214378 1.153225806 1.201242619 1.016103139 1.015793532 0.746382094 0.917683736 1.248188771 1.147932738 1 10.67115087 -5.77471763 3.208137398 1.072819983 0.957106213 0.152850699 0.130199507 0.382116385 8.152243715 0.019577422 0.039317393 1.68E-06 5.77471763 -0.11571377 STPFIVPS(ph)SPTEQEGR ddPTM_HeLa_Curcumin_4h_R1 3 STPFIVPSSPTEQEGR 16 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 STPFIVPS(0.487)S(0.487)PT(0.026)EQEGR;STPFIVPS(0.831)S(0.143)PT(0.025)EQEGR;S(0.03)T(0.001)PFIVPS(0.909)S(0.059)PT(0.001)EQEGR ;; 191.63 3.65E-07 1553320000 13419.8 11675.4 14126.6 12763.3 13838.2 15812.7 13905.2 12781 13014.8 11989.9 TRUE FALSE FALSE 12357.60867 12684.56955 14650.14422 12710.48885 13673.1885 12532.96777 14295.34249 16677.86806 11587.109 12406.54813 0.996055352 1.022409248 1.180839672 1.024498411 1.102094503 1.010189751 1.15224173 1.344279479 0.933951078 1 13.59881415 -1 0.616411512 1.012756921 23.76746937 0.68359607 0.064541601 67.13748757 0.452660461 0.010656431 2072.862839 0.1 1 22.75471245 STPFIVPSS(ph)PTEQEGR ddPTM_HeLa_Curcumin_4h_R1 1 STPFIVPSSPTEQEGR 16 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 STPFIVPS(0.137)S(0.85)PT(0.013)EQEGR 252.1 4.70E-40 275720000 2601.3 2304 2390 2161.9 2581.1 2594.6 2109 2038 2378.7 1883 TRUE FALSE FALSE 2395.40436 2503.147494 2478.575502 2152.954631 2550.322068 2056.450713 2168.172864 2659.376818 2117.762561 1948.43411 1.229399726 1.284697019 1.272085871 1.104966609 1.308908551 1.055437647 1.112777103 1.36487901 1.08690489 1 10.92809943 -9.168249404 0.894937285 0.99863528 1.211016645 0.322182357 0.097194521 0.453959144 0.649483675 0.062850514 0.017544772 6.79E-10 9.168249404 0.212381366 STPKEDDSSASTS(ph)QSTR ddPTM_HeLa_Curcumin_4h_R1 1 STPKEDDSSASTSQSTR 17 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 STPKEDDSSAS(0.015)T(0.082)S(0.483)QS(0.338)T(0.082)R 81.016 0.0038912 8995600 2848.3 2964.1 2449.4 3390 2866.1 5024.7 3654.6 4893.8 4245 3544.8 TRUE FALSE FALSE 2622.854049 3220.303596 2540.176919 3375.973078 2831.923629 3982.52058 3757.13824 6385.897092 3779.33412 3667.981536 0.715067408 0.877949784 0.692527183 0.920389878 0.772065945 1.085752625 1.024306748 1.74098398 1.030358 1 11.84077066 STPKEDDSSASTSQSTR ddPTM_HeLa_Curcumin_4h_R1 3 STPKEDDSSASTSQSTR 17 1 E7EX17;P23588-2;P23588;F8VX11 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 0 ;; ;; 125.39 0.00022545 9605800 4215.5 3788.93 3538.39 4073.75 3486.92 4843.38 3756.7 3751.26 4693.89 4106.52 FALSE FALSE TRUE 3881.838727 4116.428226 3669.525846 4056.893902 3445.340756 3838.808392 3862.102891 4895.001905 4178.982011 4249.221264 0.913541208 0.968748853 0.863576081 0.95473821 0.810816981 0.903414568 0.908896631 1.151976233 0.983470088 1 12.05298275 -9.315146599 0.893167967 1.00287875 0.92690607 0.06134191 0.084823313 1.276642805 1.711853643 0.066746675 0.015267462 4.84E-10 9.315146599 -0.07597268 STPKEETVNDPEEAGHR ddPTM_HeLa_Curcumin_4h_R1 1 STPKEETVNDPEEAGHR 17 1 O00567 O00567 NOP56 Nucleolar protein 56 0 0 55.755 0.013103 1194500 646.24 377.9 429.78 745.43 646.03 628.74 539.03 349.7 757.33 523.51 FALSE FALSE TRUE 595.0894221 410.5639921 445.7080249 742.3456082 638.3265142 498.3322366 554.1537311 456.3219202 674.2527937 541.7019335 1.098555101 0.757914947 0.822792014 1.370394976 1.178372228 0.91993808 1.022986437 0.842385622 1.244693349 1 9.08135543 -3.914837638 1.502245551 1.036968096 0.584761162 0.105165554 0.177912178 5.380122061 5.584221531 0.024345815 4.646179667 0.000121664 3.914837638 -0.452206934 GMDS(ph)EDDLRDEVEDAVQK ddPTM_HeLa_Curcumin_4h_R1 2 GMDSEDDLRDEVEDAVQK 18 1 Q5T2D3 Q5T2D3 OTUD3 OTU domain-containing protein 3 1 0 GMDS(1)EDDLRDEVEDAVQK;GMDS(1)EDDLRDEVEDAVQK ; 83.065 0.0023266 21151300 8255.1 6812.1 8047.5 7142.5 7326.3 7701.7 5437.3 2433.29 7985.9 7571.7 TRUE FALSE FALSE 7601.700124 7400.90757 8345.747429 7112.946228 7238.938657 6104.280604 5589.856004 3175.18892 7109.86675 7834.816011 0.970246157 0.944617916 1.065212944 0.90786385 0.923944946 0.779122394 0.713463596 0.405266558 0.907470799 1 12.93568368 -4.130802265 0.772618633 0.986999984 7.74E-21 0.926583147 0.048804118 0.416966947 0.155089643 0.006288552 0.37078032 7.40E-05 4.130802265 -0.986999984 down STPPHPCSLEDNVITVFSS(ph)VK ddPTM_HeLa_Curcumin_4h_R1 1 STPPHPCSLEDNVITVFSSVK 21 0 A8MQ11;A4D2B8 A8MQ11 PMS2P5;PMS2P1 Postmeiotic segregation increased 2-like protein 5;Putative postmeiotic segregation increased 2-like protein 1 1 0 STPPHPCS(0.005)LEDNVIT(0.165)VFS(0.139)S(0.689)VK 50.827 0.014327 17255000 2098.9 1623.9 1630 1535.5 1762.4 2034.5 1559.8 1114 1874.2 1808.2 TRUE FALSE FALSE 1932.76985 1764.26268 1690.409234 1529.146508 1741.384531 1612.521766 1603.56379 1453.653472 1668.604949 1871.034815 1.032995129 0.94293418 0.903462202 0.817273145 0.930706643 0.861834186 0.857046473 0.776924865 0.891808605 1 10.86962069 -6.850881034 1.923140463 1.015584778 0.854723591 0.456287795 0.055092541 0.106730581 0.803206446 0.00661974 0.009190918 1.41E-07 6.850881034 -0.160861187 STPQPPS(ph)GKT(ph)TPNSGDVQVTEDAVR ddPTM_HeLa_Curcumin_4h_R1 1 STPQPPSGKTTPNSGDVQVTEDAVR 25 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 2 0 S(0.152)T(0.067)PQPPS(0.915)GKT(0.688)T(0.173)PNS(0.005)GDVQVTEDAVR 61.904 0.0058515 10117000 1857.2 1700.2 1255.2 1842.3 1999.6 2621.5 2560.2 2020.4 1768.7 2039.4 TRUE FALSE FALSE 1710.20066 1847.157712 1301.718816 1834.677051 1975.756076 2077.77135 2632.032322 2636.410659 1574.678035 2110.268998 0.810418322 0.875318603 0.616849708 0.869404352 0.936257926 0.984600234 1.247249675 1.249324452 0.746197777 1 11.0432112 -4.867788874 2.122465843 0.880965596 1.271278684 0.692998295 0.105597454 0.167379987 1.444714242 0.016755815 0.078237016 1.36E-05 4.867788874 0.390313088 STPRPSLPMEK(ac)IVIK ddPTM_HeLa_Curcumin_4h_R1 1 STPRPSLPMEKIVIK 15 2 A0A087X0G5;Q8IZL2 A0A087X0G5 MAML2 Mastermind-like protein 2 0 1 STPRPSLPMEK(1)IVIK 77.192 0.0079046 570600 0 160.36 148.43 0 57.858 0 82.336 0 0 0 FALSE TRUE FALSE 0 174.2208038 153.9309464 0 57.16808114 0 84.64612656 0 0 0 0 STPS(ph)PTPVESSDPK ddPTM_HeLa_Curcumin_4h_R1 2 STPSPTPVESSDPK 14 0 Q9NW07 Q9NW07 ZNF358 Zinc finger protein 358 1 0 S(0.003)T(0.001)PS(0.981)PT(0.014)PVESSDPK;S(0.042)T(0.007)PS(0.943)PT(0.007)PVESSDPK ; 197.06 2.38E-06 89041000 8321.9 6524.4 7400.9 8366.9 8242.9 10326.5 8429.6 7656.7 8425.8 6931.5 TRUE FALSE FALSE 7663.212834 7088.340064 7675.183864 8332.279985 8144.608801 8184.667496 8666.111889 9991.192583 7501.51082 7172.369109 1.068435369 0.988284339 1.070104417 1.161719351 1.135553494 1.141138635 1.208263512 1.39301149 1.045890236 1 12.80823402 -1 0.346548023 1.02146209 5.01091043 0.880747129 0.038936538 12.93652704 0.162477905 0.012192637 34.05885665 0.1 1 3.98944834 STPSHGSVSSLNSTGS(ph)LSPK ddPTM_HeLa_Curcumin_4h_R1 1 STPSHGSVSSLNSTGSLSPK 20 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 0 STPSHGSVS(0.007)S(0.02)LNS(0.003)T(0.025)GS(0.882)LS(0.062)PK 75.764 0.0019275 13279000 2244.7 1936 1743.3 1675 2603 4618.9 2000.5 1426.6 2670.2 2084 TRUE FALSE FALSE 2067.029626 2103.339213 1807.908232 1668.069294 2571.960925 3660.888074 2056.628646 1861.563773 2377.285741 2156.418845 0.958547377 0.975385287 0.838384545 0.773536782 1.192700078 1.697670229 0.953724111 0.863266326 1.102423004 1 11.07442171 -5.68817524 12.17017752 0.954802675 1.198451326 0.209096969 0.221848682 0.803944094 130.8126394 0.031556602 0.063118636 2.05E-06 5.68817524 0.24364865 STPVNVPISQK ddPTM_HeLa_Curcumin_4h_R1 2 STPVNVPISQK 11 0 Q8WUM4;Q8WUM4-2 Q8WUM4 PDCD6IP Programmed cell death 6-interacting protein 0 0 ; ; 152.69 3.51E-07 5196200 2564.7 2464.5 2304.8 2619 2255.39 2829.8 1786.3 2236.9 2679.2 2571.7 FALSE FALSE TRUE 2361.701289 2677.520398 2390.217916 2608.163272 2228.495947 2242.867582 1836.41877 2918.920513 2385.298463 2661.066384 0.887501831 1.006183241 0.898218072 0.980119582 0.837444703 0.842845408 0.690106335 1.096898796 0.896369395 1 11.37778879 -5.755419333 24.97286954 0.948604104 0.852488376 0.11768761 0.101180292 187.5572639 778032.9654 0.013747821 0.026938541 1.76E-06 5.755419333 -0.096115728 STPVTVVLPDTK ddPTM_HeLa_Curcumin_4h_R1 1 STPVTVVLPDTK 12 0 Q15029-3;Q15029;Q15029-2 Q15029-3 EFTUD2 116 kDa U5 small nuclear ribonucleoprotein component 0 0 134.13 0.00032166 2360900 1405.4 1136 1209.6 1564.1 1219.4 1452.3 1210.9 1256.5 1489 1269.2 FALSE FALSE TRUE 1294.161107 1234.190778 1254.42884 1557.628169 1204.859451 1151.076609 1244.874595 1639.601066 1325.660425 1313.304606 0.985423413 0.939759727 0.955169756 1.186037239 0.917425741 0.876473443 0.947894791 1.248454516 1.00940819 1 10.35898586 STQIENQHQGAQDTS(ph)DLMSPSKR ddPTM_HeLa_Curcumin_4h_R1 1 STQIENQHQGAQDTSDLMSPSKR 23 1 H0YBW3;Q9NVR2 H0YBW3 INTS10 Integrator complex subunit 10 1 0 STQIENQHQGAQDT(0.058)S(0.472)DLMS(0.332)PS(0.138)KR 54.047 0.0084467 9967100 1604.2 961.31 1423.5 1329.4 944.41 1951.4 1523.8 1241 1691.2 1363 TRUE FALSE FALSE 1477.225877 1044.401353 1476.256162 1323.899295 933.1485276 1546.657643 1566.553727 1619.375187 1505.679591 1410.364149 1.047407422 0.740518932 1.046719859 0.938693242 0.661636591 1.096637095 1.11074415 1.148196506 1.067582151 1 10.46185199 -5.027003253 24.93856146 0.972226766 1.123025577 0.266803014 0.131578508 812.5963047 750465.2093 0.018834562 0.048179464 9.40E-06 5.027003253 0.150798811 STS(ph)ATDTHHVEMAR ddPTM_HeLa_Curcumin_4h_R1 1 STSATDTHHVEMAR 14 0 H3BQP2;H3BNP3;H3BTL2;H3BS02;O14874-2;O14874-3;O14874 H3BQP2 BCKDK "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial" 1 0 S(0.01)T(0.01)S(0.783)AT(0.195)DT(0.002)HHVEMAR 124.25 0.00087004 21377000 2526 1753.7 1611.4 1908.3 2634.4 3775.5 1861.4 1748.5 2887.8 1978.4 TRUE FALSE FALSE 2326.064435 1905.282014 1671.119902 1900.40396 2602.986501 2992.418741 1913.625874 2281.609601 2571.015565 2047.149253 1.136245651 0.9307001 0.816315615 0.928317248 1.271517696 1.46174918 0.934775944 1.114530168 1.2559004 1 10.99940057 -5.756990401 24.99941001 1.025529923 1.196017435 0.22341845 0.16715111 143.9047107 808609.6742 0.023916434 0.046546078 1.75E-06 5.756990401 0.170487512 STS(ph)DTDLVTSDSR ddPTM_HeLa_Curcumin_4h_R1 2 STSDTDLVTSDSR 13 0 Q76N89-2;Q76N89 Q76N89-2 HECW1 E3 ubiquitin-protein ligase HECW1 1 0 S(0.002)T(0.002)S(0.663)DT(0.333)DLVTSDSR;ST(0.002)S(0.997)DTDLVTSDSR ; 175.88 0.00020378 23892000 2659.44 2357.07 2751.93 2772.7 2743.31 3397.8 2371.05 1889.38 3427.4 3112.1 TRUE FALSE FALSE 2448.942518 2560.804628 2853.918947 2761.227302 2710.59782 2693.057979 2437.575282 2465.443264 3051.422795 3220.245243 0.760483234 0.795220374 0.886242733 0.857458701 0.841736456 0.836289716 0.756953306 0.765607299 0.947574661 1 11.65295485 -9.38068584 1.023575476 1.003674318 0.811681407 0.677444793 0.044052916 0.249511381 0.453362222 0.035777021 0.008527015 4.16E-10 9.38068584 -0.19199291 ADSEPES(ph)PLNASYVYK ddPTM_HeLa_Curcumin_4h_R1 2 ADSEPESPLNASYVYK 16 0 Q5T1V6-2;Q5T1V6 Q5T1V6-2 DDX59 Probable ATP-dependent RNA helicase DDX59 1 0 ADS(0.013)EPES(0.987)PLNASYVYK;ADS(0.001)EPES(0.996)PLNAS(0.003)YVYK ; 168.68 2.76E-05 4340900 3747.2 2266.1 3401.1 2881.9 3519.5 4525.9 3958.5 4793.2 2721 2871.86 TRUE FALSE FALSE 3450.605166 2461.971586 3527.147758 2869.975461 3477.532261 3587.177323 4069.564856 6254.624615 2422.513108 2971.656921 1.16117212 0.828484462 1.186929666 0.965782907 1.170233426 1.207130371 1.369459855 2.104759998 0.815206187 1 11.53705185 -3.015853922 0.923009821 1.060691112 10.63138361 0.866222934 0.128130794 3.527111508 0.373996195 0.015770003 57.20789971 0.000964153 3.015853922 9.570692497 up STS(ph)FRGGMGSGGLATGIAGGLAGMGGIQNEK ddPTM_HeLa_Curcumin_4h_R1 4 STSFRGGMGSGGLATGIAGGLAGMGGIQNEK 31 1 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 S(0.053)T(0.185)S(0.567)FRGGMGS(0.134)GGLAT(0.06)GIAGGLAGMGGIQNEK;S(0.084)T(0.084)S(0.413)FRGGMGS(0.413)GGLAT(0.005)GIAGGLAGMGGIQNEK;S(0.373)T(0.148)S(0.422)FRGGMGS(0.054)GGLAT(0.004)GIAGGLAGMGGIQNEK;S(0.388)T(0.14)S(0.448)FRGGMGS(0.021)GGLAT(0.002)GIAGGLAGMGGIQNEK ;;; 89.396 1.13E-06 315630500 7147.61 5434 5727.75 5823.93 5156.64 7146.69 5726.13 11951.3 7332.4 5987.9 TRUE FALSE FALSE 6581.869126 5903.690747 5940.025454 5799.832121 5095.150436 5664.385934 5886.789797 15595.19635 6528.054065 6195.979079 1.062280721 0.952826127 0.958690366 0.936063864 0.822331769 0.914203528 0.950098398 2.516986606 1.05359524 1 12.59711656 -4.26056712 24.99964556 0.9884635 2.516987084 0.977799411 0.070222937 8.68665933 248925.1105 0.011609677 0.094053632 5.49E-05 4.26056712 1.528523584 STS(ph)LGSNLSELDR ddPTM_HeLa_Curcumin_4h_R1 2 STSLGSNLSELDR 13 0 P49023-4;F8W1E0;F8W0G0;F8W0K8 P49023-4 PXN Paxillin 1 0 S(0.017)T(0.055)S(0.929)LGSNLSELDR;ST(0.012)S(0.987)LGS(0.001)NLSELDR ; 142.95 0.00086355 29190300 5673.2 4546.9 4676.1 6384.1 5039.3 1784.39 1996 2107.9 5526.7 4851.4 TRUE FALSE FALSE 5224.160234 4939.913775 4849.40038 6357.684286 4979.209639 1414.2874 2052.002388 2750.589006 4920.434837 5019.985789 1.040672315 0.984049355 0.966018747 1.266474559 0.991877238 0.281731355 0.408766573 0.547927648 0.980169077 1 12.29346756 -5.272076591 22.92699039 1.030267436 0.412404344 0.887286111 0.101252694 47.43290831 102235.2631 0.013794662 0.031205158 5.34E-06 5.272076591 -0.617863092 STS(ph)LSALVR ddPTM_HeLa_Curcumin_4h_R1 2 STSLSALVR 9 0 Q5VZ89-3;Q5VZ89;Q5VZ89-7;X6RAE7;Q5VZ89-5;X6R5W5;A0A0A0MRX3 Q5VZ89-3 DENND4C DENN domain-containing protein 4C 1 0 S(0.013)T(0.043)S(0.901)LS(0.043)ALVR;S(0.008)T(0.033)S(0.861)LS(0.098)ALVR ; 123.96 0.0052106 34787000 5071.3 3834.4 4174.84 4674 4211.97 6377.1 5364.3 5754.5 4476.12 4924.8 TRUE FALSE FALSE 4669.901254 4165.82845 4329.563243 4654.660226 4161.745009 5054.417575 5514.807821 7509.02056 3985.100835 5095.936433 0.916397077 0.817480458 0.84961092 0.913406258 0.816679145 0.991852556 1.082197137 1.473531049 0.782015413 1 12.31513157 -4.212706419 1.754784892 0.928464872 1.702850146 0.837045153 0.077634446 0.309339437 0.847174995 0.010896903 0.413196624 6.13E-05 4.212706419 0.774385274 STS(ph)PPPSPEVWADSR ddPTM_HeLa_Curcumin_4h_R1 2 STSPPPSPEVWADSR 15 0 E5RJ61;E5RGQ7;E5RJC0;E5RGQ0;E5RFK4;Q08495-3;Q08495-2;Q08495 E5RJ61 DMTN Dematin 1 0 ST(0.002)S(0.997)PPPSPEVWADSR;S(0.001)T(0.001)S(0.999)PPPSPEVWADSR ; 132.24 0.00068071 15007000 4579.7 3846.8 3952.6 4170.2 3657.5 5241 3779.2 1924.43 4588.3 3562.3 TRUE FALSE FALSE 4217.211913 4179.300251 4099.086833 4152.944817 3613.886701 4153.957522 3885.234181 2511.179848 4084.974969 3686.08966 1.144088262 1.1338032 1.112042086 1.126653229 0.980412045 1.126927966 1.054025957 0.681258482 1.108213675 1 11.84787545 -4.263276705 4.843009137 1.078713336 0.660243653 0.832761968 0.05458034 0.062508091 4.257193032 0.009144156 0.08759428 5.45E-05 4.263276705 -0.418469683 STS(ph)PSAAGGQQK ddPTM_HeLa_Curcumin_4h_R1 1 STSPSAAGGQQK 12 0 Q2TB10 Q2TB10 ZNF800 Zinc finger protein 800 1 0 S(0.002)T(0.006)S(0.981)PS(0.011)AAGGQQK 114.87 0.0041323 2323400 2458.7 4459.5 2953.3 2497.8 2326.8 1997.4 1390.6 956.41 2128.3 2274.3 TRUE FALSE FALSE 2264.091301 4844.959309 3062.751896 2487.464765 2299.05443 1583.116725 1429.616493 1248.015006 1894.830815 2353.331756 0.962079101 2.058765959 1.301453519 1.056997068 0.976935965 0.67271294 0.607486169 0.530318347 0.805169441 1 11.200489 -5.276906346 2.026359086 1.102507756 0.56726034 0.380118314 0.328112057 0.33285818 2.619764864 0.051667706 0.158999672 5.29E-06 5.276906346 -0.535247416 TQASSS(ph)PAALKPPAGR ddPTM_HeLa_Curcumin_4h_R1 1 TQASSSPAALKPPAGR 16 1 H7C1J4;Q6BDS2 H7C1J4 UHRF1BP1 UHRF1-binding protein 1 1 0 T(0.001)QAS(0.003)S(0.253)S(0.743)PAALKPPAGR 99.011 0.0013838 18327000 1805.8 1802.7 1883.7 1421.1 1472.6 1830.4 1158.2 604.92 2122.6 2080.1 TRUE FALSE FALSE 1662.869025 1958.517355 1953.511579 1415.219865 1455.040207 1450.754407 1190.695975 789.3573233 1889.75609 2152.38332 0.772571042 0.909929629 0.907603939 0.657512931 0.676013512 0.674022324 0.553198849 0.366736406 0.877983058 1 11.07171932 -4.130665489 0.284378743 0.949022371 3.93E-22 0.834367605 0.074393513 3.07620418 0.175976951 0.045031343 1.031275965 7.40E-05 4.130665489 -0.949022371 down STS(ph)PVTDPSIPIR ddPTM_HeLa_Curcumin_4h_R1 1 STSPVTDPSIPIR 13 0 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 0 S(0.001)T(0.048)S(0.793)PVT(0.158)DPSIPIR 146.79 0.00069455 51782000 4768.7 3087.4 2983.7 3494.8 3468.7 3521.6 2747.6 1632.8 4548.9 3447.4 TRUE FALSE FALSE 4391.252363 3354.261099 3094.278547 3480.339444 3427.338018 2791.180463 2824.690261 2130.633204 4049.897051 3567.196893 1.231009247 0.940307249 0.86742578 0.975651064 0.96079306 0.78245764 0.791851514 0.597285002 1.135316376 1 11.80057513 -4.79376437 0.486098797 1.099088734 0.459171452 0.723036123 0.090579672 1.356124473 0.297554238 0.027098679 0.449879389 1.61E-05 4.79376437 -0.639917282 NSEPAGLET(ph)PEAK ddPTM_HeLa_Curcumin_4h_R1 1 NSEPAGLETPEAK 13 0 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 0 NSEPAGLET(1)PEAK 102.29 0.017002 10191000 3040.4 2871.5 3048.5 3361.6 4016.4 5049.5 4806 4543 3331 2781.8 TRUE FALSE FALSE 2799.749132 3119.699665 3161.480092 3347.69059 3968.507053 4002.17678 4940.843425 5928.139787 2965.597634 2878.467343 0.972652734 1.083805822 1.098320639 1.163011489 1.378687538 1.39038464 1.7164841 2.059477868 1.030269682 1 11.49108513 -3.013428295 0.421928041 0.975473722 4.886316449 0.981198315 0.04628815 1.024920167 0.056034699 0.010513959 2.544701761 0.000969553 3.013428295 3.910842727 up STS(ph)STSSGSNSNALVPVSWK ddPTM_HeLa_Curcumin_4h_R1 1 STSSTSSGSNSNALVPVSWK 20 0 O94915;H0Y9X0;A0A286YEZ9;A0A2C9F2R7 O94915 FRYL Protein furry homolog-like 1 0 S(0.067)T(0.067)S(0.577)S(0.239)T(0.042)S(0.007)S(0.001)GS(0.001)NSNALVPVSWK 183.73 8.36E-08 10414000 2228.7 1795.5 2620.5 2687.3 2235.5 2678.8 1992.1 3502.6 2208.8 2743.4 TRUE FALSE FALSE 2052.296043 1950.695019 2717.618035 2676.180665 2208.843123 2123.186684 2047.992965 4570.526616 1966.500166 2838.732946 0.722961998 0.687171022 0.95733487 0.942737734 0.778108813 0.747934633 0.721446153 1.610058679 0.692738698 1 11.47103142 -4.255807912 24.8521771 0.843846709 1.610059036 0.805408129 0.117277193 215.951715 952983.2919 0.018483935 0.217416069 5.55E-05 4.255807912 0.766212327 STS(ph)TPNVHMVSTTLPVDSR ddPTM_HeLa_Curcumin_4h_R1 2 STSTPNVHMVSTTLPVDSR 19 0 H7C155;P04049;P04049-2 H7C155 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 0 S(0.017)T(0.017)S(0.746)T(0.22)PNVHMVSTTLPVDSR;S(0.168)T(0.168)S(0.332)T(0.332)PNVHMVSTTLPVDSR ; 108.96 0.00032291 136538000 2672.7 2409.2 2338 2377 2994 4015.8 2834.8 1852.12 3294 3186.6 TRUE FALSE FALSE 2461.152975 2617.440513 2424.648337 2367.164604 2958.298505 3182.877813 2914.336859 2416.822862 2932.656441 3297.334113 0.746406913 0.793805063 0.735335957 0.717902561 0.897178874 0.965288231 0.883846392 0.732962684 0.889402269 1 11.68708436 -9.404307439 1.123295037 1.00029064 0.808261454 0.258377582 0.084815556 0.400960956 0.902706602 0.060120498 0.015187889 3.94E-10 9.404307439 -0.192029187 STS(ph)TPTSPGPR ddPTM_HeLa_Curcumin_4h_R1 1 STSTPTSPGPR 11 0 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3;H3BUF6;H3BRB0;A0A0C4DGL7 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 0 S(0.003)T(0.003)S(0.922)T(0.054)PT(0.016)S(0.001)PGPR 208.15 1.53E-07 68500000 4691.2 3559.6 4364.3 4187.9 3972.2 5904.5 3866.4 1898.2 5386.9 5118.8 TRUE FALSE FALSE 4319.88657 3867.275963 4526.044797 4170.571579 3924.834109 4679.840143 3974.880778 2476.952442 4795.970547 5296.677919 0.815584152 0.730132363 0.854506328 0.787393843 0.740999202 0.883542517 0.750447892 0.467642639 0.905467657 1 12.37087207 -13.18131918 0.039429374 2.243124202 9.62E-13 0.497118448 0.095758166 351.3622276 1.174014167 55.89623125 19.62299843 6.59E-14 13.18131918 -2.243124202 NLNNSNLFS(ph)PVNR ddPTM_HeLa_Curcumin_4h_R1 3 NLNNSNLFSPVNR 13 0 A0A3B3ITD8;P52948-6;P52948-2;P52948-5;P52948;P52948-4;P52948-3;H0YEN4 A0A3B3ITD8 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 0 NLNNSNLFS(1)PVNR;NLNNSNLFS(1)PVNR;NLNNSNLFS(1)PVNR ;; 209.22 2.77E-09 99393000 2675.89 2720.79 2287.48 2444.5 3132.64 5115.31 5352.32 6806.52 2882.45 2055.78 TRUE FALSE FALSE 2464.090483 2955.962964 2372.256021 2434.385307 3095.285314 4054.337045 5502.491694 8881.796615 2566.252447 2127.218202 1.158362824 1.389590857 1.115191671 1.144398494 1.455085948 1.905933788 2.586707696 4.175310556 1.206388909 1 11.05475231 -3.00791959 0.651795201 1.084747232 17.97289487 0.986415858 0.109259977 0.989594742 0.084557322 0.019544923 18.15430558 0.00098193 3.00791959 16.88814764 up STS(ph)YGYSR ddPTM_HeLa_Curcumin_4h_R1 1 STSYGYSR 8 0 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 0 S(0.002)T(0.137)S(0.861)YGYSR 120.27 0.0081895 10933000 2408.2 1950.2 2337.3 2199.1 2248.1 2973.5 2567.1 1082.6 2782 2126.3 TRUE FALSE FALSE 2217.588429 2118.766598 2423.922394 2190.000707 2221.292876 2356.762582 2639.125917 1412.679756 2476.82156 2200.188767 1.007908259 0.962993099 1.101688378 0.995369461 1.009591954 1.07116381 1.199499769 0.64207207 1.125731391 1 11.10341159 -4.243620934 24.75294669 1.021734578 0.64207171 0.718006807 0.074972234 1292.660886 1795701.913 0.009045965 0.385904939 5.71E-05 4.243620934 -0.379662868 STSAPQMS(ph)PGSSDNQSS(ph)SPQPAQQK ddPTM_HeLa_Curcumin_4h_R1 2 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 2 0 STSAPQMS(0.943)PGS(0.042)S(0.015)DNQS(0.002)S(0.682)S(0.316)PQPAQQK;STSAPQMS(0.962)PGS(0.029)S(0.008)DNQSS(0.551)S(0.449)PQPAQQK ; 161.68 1.81E-09 91002000 25166.8 20458.8 22113.5 21817 20386.9 24693.9 18604.6 8671.2 25887.3 21472.1 TRUE FALSE FALSE 23174.82122 22227.16751 22933.04576 21726.72703 20143.79953 19572.10678 19126.595 11315.00896 23047.52796 22218.25388 1.043053219 1.000401185 1.03217138 0.977877342 0.906632881 0.880902113 0.860850502 0.509266346 1.037323999 1 14.43945782 -3.881169866 0.781138621 1.016522087 6.11E-18 0.927115136 0.041065627 0.750550919 0.219680227 0.006574662 0.761826486 0.000131471 3.881169866 -1.016522087 STSAPQMS(ph)PGSSDNQSSS(ph)PQPAQQK ddPTM_HeLa_Curcumin_4h_R1 2 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 2 0 STSAPQMS(0.879)PGS(0.053)S(0.068)DNQS(0.006)S(0.388)S(0.606)PQPAQQK;STSAPQMS(0.875)PGS(0.115)S(0.01)DNQS(0.01)S(0.244)S(0.747)PQPAQQK ; 151.02 1.69E-08 85423000 21543.2 17297.3 17077.1 18230.8 16587.9 20894.3 14899.2 7062.2 20472.9 16927.7 TRUE FALSE FALSE 19838.03299 18792.40154 17709.99235 18155.36578 16390.10013 16560.58665 15317.23145 9215.43227 18227.07409 17515.93632 1.132570514 1.072874507 1.011078827 1.036505583 0.935725035 0.945458259 0.874474032 0.526117023 1.040599473 1 14.09638049 -3.917643479 0.829327677 1.057495226 3.81E-19 0.906993993 0.048736756 0.971279026 0.331688083 0.009764621 1.07368475 0.000120881 3.917643479 -1.057495226 STSAPQMS(ph)PGSSDNQSSSPQPAQQK ddPTM_HeLa_Curcumin_4h_R1 4 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 0 STSAPQMS(0.94)PGS(0.059)S(0.001)DNQSSSPQPAQQK;STSAPQMS(0.701)PGS(0.242)S(0.057)DNQSSSPQPAQQK;S(0.001)T(0.001)S(0.003)APQMS(0.277)PGS(0.277)S(0.277)DNQS(0.055)S(0.055)S(0.055)PQPAQQK;S(0.002)TSAPQMS(0.985)PGS(0.011)S(0.001)DNQSSSPQPAQQK ;;; 162.01 3.15E-18 184333500 16727.2 13993.3 14093.5 15071.3 15331.7 18699.4 16116.1 21839.6 16982.1 14012.4 TRUE FALSE FALSE 15403.22447 15202.8185 14615.81751 15008.93895 15148.87949 14820.93365 16568.27439 28498.3935 15119.20612 14499.32986 1.062340441 1.0485187 1.008034002 1.035147079 1.044798597 1.022180597 1.142692425 1.965497287 1.042752063 1 13.8236986 -4.254829756 3.323510079 1.031561441 2.09898969 0.995653937 0.018366682 0.019914814 0.352646392 0.003582453 0.054560523 5.56E-05 4.254829756 1.067428249 STSAPQMSPGSS(ph)DNQSSS(ph)PQPAQQK ddPTM_HeLa_Curcumin_4h_R1 1 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 2 0 S(0.001)TS(0.001)APQMS(0.135)PGS(0.408)S(0.447)DNQS(0.128)S(0.437)S(0.443)PQPAQQK 54.311 0.0080849 18460000 3389.3 2420.7 2766.6 2922.4 2794 3260.1 2060.2 1299.9 3481.8 2873.7 TRUE FALSE FALSE 3121.033329 2629.934522 2869.13263 2910.307883 2760.683375 2583.918511 2118.003667 1696.233526 3099.855251 2973.560861 1.049594568 0.884439446 0.964881085 0.978728205 0.928409911 0.868964394 0.712278566 0.570438476 1.042472442 1 11.53797589 -3.818994099 0.576887317 1.014609263 3.73E-16 0.913104746 0.042610469 1.092641975 0.173111815 0.008463802 0.829063947 0.000151707 3.818994099 -1.014609263 AS(ph)PGLLPVANGNSLNK ddPTM_HeLa_Curcumin_4h_R1 2 ASPGLLPVANGNSLNK 16 0 Q14814-4;Q14814;Q14814-6;Q14814-3;Q14814-5;Q14814-2 Q14814-4 MEF2D Myocyte-specific enhancer factor 2D 1 0 AS(1)PGLLPVANGNSLNK;AS(0.998)PGLLPVANGNS(0.002)LNK ; 193.3 2.98E-07 164313000 7059 5087.9 5638 6028.7 5269.2 6002.2 4459.2 1599.77 6351.1 4431.7 TRUE FALSE FALSE 6500.272701 5527.675405 5846.94924 6003.754837 5206.368231 4757.276061 4584.313151 2087.532509 5654.40022 4585.701245 1.417508981 1.20541551 1.275039286 1.30923375 1.135348326 1.037415175 0.999697299 0.455226452 1.233050283 1 12.16292665 -4.130445598 1.210583044 1.211355318 1.88E-17 0.811578196 0.110202493 0.914185011 0.904779396 0.023924259 1.489574361 7.41E-05 4.130445598 -1.211355318 down STSIQSFK ddPTM_HeLa_Curcumin_4h_R1 1 STSIQSFK 8 0 P13797;A0A0A0MSQ0;P13797-3;P13797-2 P13797 PLS3 Plastin-3 0 0 101.64 0.0072591 0 1045.6 906.3 1089.7 896.55 1015 1320.7 978.27 839.64 1244.1 1049.1 FALSE FALSE TRUE 962.8396567 984.6365336 1130.085241 892.8403137 1002.896788 1046.771933 1005.717623 1095.642371 1107.625343 1085.556147 0.886955188 0.907034184 1.041019614 0.822472717 0.923855289 0.964272494 0.926453805 1.009291296 1.020329852 1 10.08421863 -9.576826917 1.377059859 0.999777182 0.92800201 0.191686564 0.058798705 0.595680396 2.035285823 0.039138679 0.009271959 2.65E-10 9.576826917 -0.071775172 STSIQSFK(ac)DK ddPTM_HeLa_Curcumin_4h_R1 1 STSIQSFKDK 10 1 P13797;A0A0A0MSQ0;P13797-3;P13797-2 P13797 PLS3 Plastin-3 0 1 STSIQSFK(1)DK 164.33 8.15E-10 2613100 943.02 755.49 716.97 623.56 791.37 1486.2 907.84 683.41 1673.5 764.21 FALSE TRUE FALSE 868.3789719 820.7911892 743.5415389 620.9798739 781.9334296 1177.945367 933.3115471 891.778563 1489.921237 790.7662406 1.098148767 1.037969437 0.940279821 0.785288802 0.988830061 1.48962526 1.180262256 1.127739801 1.884148767 1 9.627107471 -5.305167274 24.99576226 1.015140748 1.257314648 0 0.299773076 307.7261614 175902.0849 0.01817754 0.040646448 4.95E-06 5.305167274 0.2421739 QPGQVIGATTPSTGS(ph)PTNK ddPTM_HeLa_Curcumin_4h_R1 2 QPGQVIGATTPSTGSPTNK 19 0 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 0 QPGQVIGATTPS(0.001)T(0.018)GS(0.915)PT(0.066)NK;QPGQVIGAT(0.006)T(0.069)PS(0.259)T(0.085)GS(0.29)PT(0.29)NK ; 285.34 1.35E-69 32619000 14864.7 11869.6 12879.1 12981.3 13947.1 14680 10114.9 3924.6 13234 11586.1 TRUE FALSE FALSE 13688.14331 12895.55533 13356.41078 12927.58682 13780.78994 11635.20252 10398.69687 5121.192473 11782.26331 11988.71611 1.141752226 1.075641062 1.114081829 1.078312865 1.149480045 0.970512807 0.867373685 0.427167715 0.982779407 1 13.54938955 -4.130225192 1.382605927 1.077736374 1.00E-09 0.925842326 0.055172592 0.336497624 0.448762312 0.008887345 0.547186849 7.41E-05 4.130225192 -1.077736373 down STSMDSGS(ph)SESPASLK ddPTM_HeLa_Curcumin_4h_R1 1 STSMDSGSSESPASLK 16 0 Q15811;Q15811-3;F8W7U0;Q15811-7;Q15811-8;Q15811-9;Q15811-2;Q15811-4;Q15811-10;Q15811-11;Q15811-12;Q15811-6;H0Y7J7 Q15811 ITSN1 Intersectin-1 1 0 STSMDS(0.069)GS(0.43)S(0.43)ES(0.069)PAS(0.001)LK 98.421 0.0038696 10391000 2956.1 2638.1 2827.8 3021 3200.1 3601.1 2429.8 948.08 2582.4 2355.1 TRUE FALSE FALSE 2722.121566 2866.125609 2932.600756 3008.499902 3161.940898 2854.191267 2497.973649 1237.145228 2299.117181 2436.93955 1.117024657 1.176116826 1.203394953 1.234540226 1.297504855 1.17121956 1.025045389 0.507663486 0.943444486 1 11.25085475 -4.269609506 3.458755245 1.111756782 0.437879108 0.767520442 0.103349729 0.120040014 2.460784024 0.016158426 0.209083661 5.38E-05 4.269609506 -0.673877674 STSPVT(ph)DPSIPIR ddPTM_HeLa_Curcumin_4h_R1 1 STSPVTDPSIPIR 13 0 A0A087WU18;Q99607 A0A087WU18 ELF4 ETS-related transcription factor Elf-4 1 0 S(0.085)T(0.011)S(0.207)PVT(0.696)DPSIPIR 193 1.75E-05 101060000 3508.6 2650.4 2860.4 3192.6 3102.9 3367.3 2112.2 1604.8 3304.8 3013.1 TRUE FALSE FALSE 3230.890608 2879.488766 2966.40894 3179.389867 3065.899944 2668.884023 2171.462647 2094.096132 2942.271708 3117.805001 1.036270904 0.923562816 0.951441459 1.019752636 0.983352052 0.856013773 0.696471603 0.671657186 0.943699721 1 11.60631498 -4.952180328 1.846589886 1.004911623 0.663029427 0.901241167 0.03846205 0.069924964 0.44724153 0.0055728 0.025786574 1.12E-05 4.952180328 -0.341882196 STSQGS(ph)INSPVYSR ddPTM_HeLa_Curcumin_4h_R1 2 STSQGSINSPVYSR 14 0 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4;A0A494C1P1;A0A494C1G0;H0Y7N6;F6XFR5 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 STSQGS(0.925)INS(0.075)PVYSR;S(0.033)T(0.004)S(0.173)QGS(0.789)INS(0.001)PVYSR ; 281.68 2.58E-63 115491400 3044.91 2796.3 2665.44 2651.36 2373.95 3964.7 3025.13 1172.71 2955.63 2256.84 TRUE FALSE FALSE 2803.902161 3037.999712 2764.223551 2640.389375 2345.642197 3142.376529 3110.007006 1530.263881 2631.404784 2335.265022 1.200678353 1.300922886 1.183687301 1.130659411 1.004443682 1.345618805 1.331757628 0.655284889 1.126812057 1 11.18937057 -9.322454741 1.104957353 1.002082821 1.160626596 0.00555675 0.19497555 0.965836063 2.152320862 0.11433517 0.03190603 4.76E-10 9.322454741 0.158543774 STSQGSINS(ph)PVYSR ddPTM_HeLa_Curcumin_4h_R1 2 STSQGSINSPVYSR 14 0 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4;A0A494C1P1;A0A494C1G0;H0Y7N6;F6XFR5 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 STSQGS(0.003)INS(0.997)PVYSR;STSQGS(0.017)INS(0.983)PVYSR ; 268.13 3.49E-50 46356000 4368.9 3817.9 3660.5 3581.3 4060.6 5546.2 3985.6 709.7 4695.5 3400.5 TRUE FALSE FALSE 4023.096955 4147.902264 3796.16135 3566.48153 4012.179997 4395.855601 4097.425209 926.0842629 4180.415398 3518.667122 1.143358214 1.178827698 1.07886345 1.013588784 1.14025563 1.249295671 1.164482194 0.26319178 1.188067883 1 11.78081332 -4.258543402 24.99940334 1.095286994 0.26319148 0.91152082 0.080281368 63.92330202 551785.8613 0.012472353 0.116441805 5.51E-05 4.258543402 -0.832095515 STST(ph)PTSPGPR ddPTM_HeLa_Curcumin_4h_R1 2 STSTPTSPGPR 11 0 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3;H3BUF6;H3BRB0;A0A0C4DGL7 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 0 STS(0.028)T(0.967)PT(0.005)SPGPR;STS(0.034)T(0.964)PT(0.001)SPGPR ; 155.26 0.0012696 46207000 7484.8 6954.5 6622.8 7702.1 7592 14748.3 14304.4 10021.1 9111 7259.9 TRUE FALSE FALSE 6892.370182 7555.615991 6868.246794 7670.230751 7501.470358 11689.33633 14705.74297 13076.48726 8111.546095 7512.180985 0.917492563 1.005781944 0.914281326 1.021039132 0.998574232 1.556050947 1.957586352 1.740704502 1.079785765 1 12.87501611 -5.139391309 2.709764838 0.963754211 1.84714313 0.958792021 0.073630418 0.028652213 0.403946275 0.008688717 0.026499248 7.25E-06 5.139391309 0.883388919 STSTLEIQPSRAS(ph)PTSDIESVER ddPTM_HeLa_Curcumin_4h_R1 2 STSTLEIQPSRASPTSDIESVER 23 1 Q96JK2-2;Q96JK2-3;Q96JK2 Q96JK2-2 DCAF5 DDB1- and CUL4-associated factor 5 1 0 STSTLEIQPS(0.359)RAS(0.618)PT(0.016)S(0.007)DIESVER;S(0.001)T(0.001)S(0.001)T(0.001)LEIQPS(0.03)RAS(0.451)PT(0.451)S(0.057)DIES(0.006)VER ; 73.796 0.0005335 17872800 2012.54 1424.41 1504.94 1471.49 2031.42 1508.91 1345.25 937.45 1681.28 1710.63 TRUE FALSE FALSE 1853.245335 1547.529653 1560.7144 1465.401364 2007.196643 1195.945057 1382.994094 1223.27419 1496.84779 1770.074265 1.046987334 0.874273856 0.881722553 0.82787564 1.133961825 0.675646825 0.781319813 0.691086365 0.845641237 1 10.78959418 -3.525463341 0.325667545 1.026861794 0.198264829 0.267916052 0.120313812 6.300757301 0.330526381 0.037782225 2.265305036 0.00029822 3.525463341 -0.828596964 STSTPNVHMVS(ph)TTLPVDSR ddPTM_HeLa_Curcumin_4h_R1 1 STSTPNVHMVSTTLPVDSR 19 0 H7C155;P04049;P04049-2 H7C155 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 0 STS(0.002)T(0.008)PNVHMVS(0.952)T(0.03)T(0.008)LPVDSR 104.41 0.00081846 7071000 1061 1013.3 1051.5 1006.9 1241.2 1457.6 963.33 658.51 1145.3 950.68 TRUE FALSE FALSE 977.0207304 1100.885137 1090.469515 1002.733715 1226.399501 1155.277329 990.3584471 859.2866676 1019.663455 983.7160592 0.99319384 1.119108636 1.108520599 1.019332464 1.246700701 1.174401209 1.006752343 0.873510867 1.036542451 1 9.942098145 -7.275336405 22.93917768 0.996785971 1.084641836 0.088907455 0.096223784 375.5816201 619953.2172 0.016595285 0.019044436 5.30E-08 7.275336405 0.087855865 STSTPTS(ph)PGPR ddPTM_HeLa_Curcumin_4h_R1 3 STSTPTSPGPR 11 0 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3;H3BUF6;H3BRB0;A0A0C4DGL7 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 0 STST(0.003)PT(0.009)S(0.988)PGPR;STSTPTS(1)PGPR;ST(0.003)S(0.017)T(0.09)PT(0.09)S(0.799)PGPR ;; 139.31 0.0014516 24551500 18408.7 13936.7 15122.2 16467 16537.2 10819.1 5745.1 8430.9 16196.3 12913.6 TRUE FALSE FALSE 16951.63197 15141.32625 15682.64203 16398.86392 16340.00469 8575.096704 5906.292044 11001.4426 14419.60641 13362.34664 1.268611901 1.133133772 1.173644305 1.227244313 1.222839456 0.641735837 0.44201009 0.82331666 1.079122313 1 13.70588577 -5.25434245 23.66610514 1.146915813 0.616319665 0.816764765 0.113132291 91.4197291 304854.2707 0.018382402 0.045714889 5.57E-06 5.25434245 -0.530596148 STSVTNDK(ac)LTSK ddPTM_HeLa_Curcumin_4h_R1 1 STSVTNDKLTSK 12 1 G5E9C0;Q9HB58-5;Q9HB58-3;Q9HB58-7;Q9HB58;Q9HB58-6;C9JZQ4;E7EM70 G5E9C0 SP110 Sp110 nuclear body protein 0 1 STSVTNDK(1)LTSK 80.17 0.016382 0 0 0 0 0 0 72.249 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 57.26374299 0 0 0 0 0 STSYGYS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 STSYGYSR 8 0 Q13242 Q13242 SRSF9 Serine/arginine-rich splicing factor 9 1 0 STSYGYS(1)R 105.17 0.012708 322160000 2978.2 2575.7 2495.2 2611.5 3098.9 2613.9 1821.2 2192.3 2112.3 2531.4 TRUE FALSE FALSE 2742.472327 2798.332031 2587.674307 2600.694305 3061.947641 2071.747675 1872.29797 2860.722178 1880.585975 2619.365962 1.046998536 1.068324194 0.987901021 0.992871688 1.168965195 0.790934793 0.714790525 1.092142992 0.717954651 1 11.35500192 -5.244886897 24.97218587 1.029793404 0.850839539 0.122977568 0.142381163 596.2412523 899527.9537 0.013198949 0.033544891 5.69E-06 5.244886897 -0.178953864 STT(ph)PGGTGIKPFLER ddPTM_HeLa_Curcumin_4h_R1 1 STTPGGTGIKPFLER 15 1 Q9NQW6;Q9NQW6-2 Q9NQW6 ANLN Actin-binding protein anillin 1 0 S(0.005)T(0.017)T(0.977)PGGTGIKPFLER 146.27 0.0046053 33423000 2445 2242.5 1796.9 2357.8 2145 3907.4 3997.8 1271 2276.9 1715.3 TRUE FALSE FALSE 2251.47567 2436.331708 1863.494695 2348.044048 2119.422276 3096.961195 4109.967508 1658.522049 2027.129767 1774.906547 1.268503783 1.372653513 1.049911443 1.322911368 1.194103588 1.744858736 2.315596567 0.934427816 1.14210507 1 10.79352735 -5.273832582 6.684204546 1.160940929 1.731330138 0.289675705 0.331444747 0.112060559 26.70346426 0.043817733 0.103107556 5.32E-06 5.273832582 0.570389209 STT(ph)PPPAEPVSLPQEPPK ddPTM_HeLa_Curcumin_4h_R1 4 STTPPPAEPVSLPQEPPK 18 0 Q9UN86-2;Q9UN86 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 0 S(0.028)T(0.005)T(0.967)PPPAEPVSLPQEPPK;S(0.143)T(0.143)T(0.713)PPPAEPVSLPQEPPK;S(0.141)T(0.141)T(0.717)PPPAEPVS(0.001)LPQEPPK;S(0.101)T(0.128)T(0.771)PPPAEPVSLPQEPPK ;;; 201.04 1.61E-11 132371100 32819.6 28822.4 30700.3 29053.7 32728.5 34828.9 29885.6 30131.9 27334.1 25232.7 TRUE FALSE FALSE 30221.89403 31313.67983 31838.08012 28933.48349 32338.23401 27604.99354 30724.1095 39318.9776 24335.61762 26109.53445 1.157504133 1.199319731 1.219404359 1.108157771 1.238560346 1.05727636 1.176739078 1.505924117 0.932058657 1 14.67228911 -1 0.025332857 3.71E-14 2.788595313 0.499734122 0.105382417 1211.834407 2.384483694 90.30522228 189.4236685 0.1 1 2.788595313 STT(ph)PPPAEPVSLPQEPPKPR ddPTM_HeLa_Curcumin_4h_R1 2 STTPPPAEPVSLPQEPPKPR 20 1 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 1 0 S(0.155)T(0.155)T(0.691)PPPAEPVSLPQEPPKPR;S(0.176)T(0.176)T(0.648)PPPAEPVSLPQEPPKPR ; 165.03 3.61E-06 773320000 8218.2 9802.7 8196 8792.1 9075.3 8812.7 8032.6 7900.2 7523.8 7166 TRUE FALSE FALSE 7567.720798 10650.00171 8499.75097 8755.72062 8967.082975 6984.84668 8257.973137 10308.93461 6698.457964 7415.017967 1.020593724 1.436274565 1.146288655 1.18080909 1.209313722 0.941986481 1.113682148 1.390277766 0.903363686 1 12.85623447 -7.476213191 24.99481868 1.00908529 1.189458804 0.365040151 0.134841843 364.890285 195442.2513 0.021863446 0.024914031 3.34E-08 7.476213191 0.180373513 QIDS(ph)SPVGGETDETTVSQNYR ddPTM_HeLa_Curcumin_4h_R1 1 QIDSSPVGGETDETTVSQNYR 21 0 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 QIDS(0.616)S(0.384)PVGGETDETTVSQNYR 104.77 3.29E-05 32990000 2939.7 2365.5 2426.3 2449.2 2517.3 2939.6 1849.7 824.99 2870.9 2485.1 TRUE FALSE FALSE 2707.019643 2569.96328 2516.220812 2439.065859 2487.282842 2329.893824 1901.597604 1076.525653 2555.969453 2571.45704 1.052718206 0.9994191 0.978519483 0.948515111 0.967265952 0.906059789 0.739501992 0.41864423 0.993977116 1 11.32837034 -4.129001343 0.968445914 1.015749814 3.80E-18 0.977770075 0.026778591 0.27738628 0.16755196 0.005022758 0.311466417 7.43E-05 4.129001343 -1.015749814 down S(ph)VSQDLIK ddPTM_HeLa_Curcumin_4h_R1 2 SVSQDLIK 8 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 S(0.981)VS(0.019)QDLIK;S(0.999)VS(0.001)QDLIK ; 121.29 0.0078726 43421000 4643.5 3384.5 3383.9 3909.5 5262 6605.9 6369.8 11874.6 4312.8 3896.4 TRUE FALSE FALSE 4275.962075 3677.041099 3509.310311 3893.323525 5199.254087 5235.761876 6548.519445 15495.11088 3839.69663 4031.79961 1.060559177 0.912009885 0.87040792 0.965654026 1.289561632 1.298616594 1.62421749 3.843224459 0.952353044 1 11.97720822 -2.91977928 1.0558432 1.012916392 43.36222516 0.980771187 0.117840039 2.341608418 0.20620001 0.018430954 205.835143 0.001202876 2.91977928 42.34930876 up STTPPPAEPVSLPQEPPKPR ddPTM_HeLa_Curcumin_4h_R1 1 STTPPPAEPVSLPQEPPKPR 20 1 Q9UN86-2 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 0 0 63.392 0.010439 5983000 1393.7 1291.3 1392.5 1550.7 1507.8 1701.6 1266 1111.1 1498 1297.1 FALSE FALSE TRUE 1283.387174 1402.914218 1444.107275 1544.283614 1489.82047 1348.668979 1301.520553 1449.869275 1333.673148 1342.174128 0.956200203 1.045255 1.075946291 1.150583655 1.110005355 1.004839052 0.969710655 1.080239325 0.993666261 1 10.39035614 -7.132275831 4.784820257 0.979457009 1.063763255 0.360972672 0.048622599 0.193453724 6.764741805 0.00902542 0.011125274 7.37E-08 7.132275831 0.084306246 STTQELMEDDR ddPTM_HeLa_Curcumin_4h_R1 1 STTQELMEDDR 11 0 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 0 0 133.75 0.011946 6565300 2462.1 2580.4 2247.9 2673.6 2567.7 2714.2 2154.6 1703.2 2669.2 2146.3 FALSE FALSE TRUE 2267.222187 2803.438278 2331.209151 2662.537352 2537.081855 2151.244325 2215.052277 2222.497839 2376.395438 2220.883765 1.020864857 1.26230752 1.049676344 1.198863891 1.142374893 0.968643365 0.997374249 1.000726771 1.070022428 1 11.11691817 -3.282921528 14.02167513 1.044604012 1.064023849 0 0.096902448 0 0 0.013498647 0 0.000521289 3.282921528 0.019419836 STTSVS(ph)EEDVSSR ddPTM_HeLa_Curcumin_4h_R1 2 STTSVSEEDVSSR 13 0 Q96IZ0 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 1 0 STTS(0.008)VS(0.985)EEDVS(0.007)SR;STTSVS(0.987)EEDVS(0.012)SR ; 182.72 0.00010712 76770000 3302.4 2772.9 3135.3 3027.6 3330 3054.1 2390.4 2120.3 2452.7 2628.2 TRUE FALSE FALSE 3041.011555 3012.57712 3251.496976 3015.072593 3290.291925 2420.645233 2457.468191 2766.769709 2183.644946 2719.529754 1.118212276 1.107756632 1.195610002 1.108674244 1.209875317 0.890096984 0.903637177 1.017370634 0.802949459 1 11.4091415 -5.240446741 24.99681777 1.084723281 0.933695146 0.24509667 0.112501111 619.3582306 737494.825 0.011541239 0.029392784 5.75E-06 5.240446741 -0.151028135 STTSVSEEDVSSR ddPTM_HeLa_Curcumin_4h_R1 2 STTSVSEEDVSSR 13 0 Q96IZ0 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 0 0 ; ; 291.24 8.60E-113 2964500 1181.11 1069.8 965.52 896.98 1087.15 1268.74 886.61 1180.01 1131.74 1108.56 FALSE FALSE TRUE 1087.623897 1162.268745 1001.303021 893.2685344 1074.186446 1005.589022 911.4858904 1539.789617 1007.590953 1147.082377 0.948165466 1.013239126 0.872912914 0.778730937 0.936451006 0.876649352 0.794612408 1.342353127 0.878394589 1 10.16375329 -8.153560614 0.789242406 0.992045612 0.928175307 0 0.153997145 1.821270087 2.457218738 0.050905029 0.033359742 7.02E-09 8.153560614 -0.063870305 STTTGHLIYK ddPTM_HeLa_Curcumin_4h_R1 3 STTTGHLIYK 10 0 A0A2U3TZH3;Q05639;A0A2R8Y488;A0A2R8Y660;A0A2R8YDN5;Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A6PW80;Q5JR01 A0A2U3TZH3;Q5VTE0 EEF1A2;EEF1A1P5;EEF1A1 Elongation factor 1-alpha 2;Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 0 ;; ;; 98.249 0.0036128 105255000 31304.4 23478.7 20449.8 18477.7 40979 64924 31950.6 28069.5 38992.9 21180 FALSE FALSE TRUE 28826.62371 25508.09421 21207.68758 18401.24417 40490.35219 51458.03056 32847.04785 36627.76133 34715.47643 21916.00342 1.315323015 1.163902638 0.967680428 0.839625903 1.847524451 2.347965985 1.498769972 1.67127923 1.584024046 1 14.41969711 -5.747189257 24.99394443 1.119188016 1.853097049 0.599155832 0.278457909 108.670827 190601.6171 0.036728661 0.073181154 1.79E-06 5.747189257 0.733909033 STVGTLFAVGGMDS(ph)T(ph)KGAT(ph)SIEK ddPTM_HeLa_Curcumin_4h_R1 1 STVGTLFAVGGMDSTKGATSIEK 23 1 Q96PQ7-5;Q96PQ7-4;Q96PQ7-6;Q96PQ7;Q96PQ7-2;Q96PQ7-3 Q96PQ7-5 KLHL5 Kelch-like protein 5 3 0 S(0.021)T(0.021)VGT(0.02)LFAVGGMDS(0.944)T(0.889)KGAT(0.553)S(0.552)IEK 46.178 0.0077894 0 3203.2 2404.1 2974.4 2985.9 2843.7 3234.9 2244.2 2304.7 3360.8 2713.4 TRUE FALSE FALSE 2949.66334 2611.899692 3084.633881 2973.545137 2809.790735 2563.945275 2307.166212 3007.39242 2992.128648 2807.690448 1.050565721 0.93026626 1.098637452 1.059071572 1.000748048 0.913186593 0.821730976 1.071126777 1.065690361 1 11.45516817 -5.366822028 4.394995009 1.025142663 0.924354748 0.267119751 0.071275143 0.205258388 6.618470793 0.009391246 0.02179765 4.30E-06 5.366822028 -0.100787915 STVNEK(ac)PK ddPTM_HeLa_Curcumin_4h_R1 2 STVNEKPK 8 1 A0A590UJS4;Q6KC79-2;Q6KC79-3;Q6KC79 A0A590UJS4;Q6KC79 NIPBL Nipped-B-like protein 0 1 ; STVNEK(1)PK;STVNEK(1)PK 135.71 0.0010899 17499200 13114 10030.5 11414.4 11541.1 11967.8 13648.7 11519.9 6321.6 12943.1 12792.5 FALSE TRUE FALSE 12076.01306 10897.49172 11837.42771 11493.34599 11825.0918 10817.80577 11843.11739 8249.026739 11523.27431 13237.03842 0.912289643 0.823257543 0.89426557 0.86827171 0.893333646 0.817237619 0.8946954 0.623177668 0.870532663 1 13.69229276 -1 0.12535658 1.044581996 0.086840443 0.382583421 0.072556279 42.41890479 0.361967566 0.228077263 7.167599985 0.1 1 -0.957741553 STVTGERQS(ph)GDGQESTEPVENK ddPTM_HeLa_Curcumin_4h_R1 4 STVTGERQSGDGQESTEPVENK 22 1 O15234;J3KSY7 O15234 CASC3 Protein CASC3 1 0 STVTGERQS(1)GDGQESTEPVENK;STVTGERQS(1)GDGQESTEPVENK;STVTGERQS(1)GDGQESTEPVENK;STVTGERQS(0.884)GDGQES(0.086)T(0.03)EPVENK ;;; 120.27 3.91E-06 639166000 11642.3 9602.8 9943.5 10216.6 10124.9 12325.2 8924 10246.1 11104.7 8905.2 TRUE FALSE FALSE 10720.79967 10432.82324 10312.01486 10174.32642 10004.16718 9768.814586 9174.383422 13370.08872 9886.542193 9214.655037 1.163451006 1.132199003 1.119088541 1.104146208 1.085680054 1.060138936 0.995629612 1.450959224 1.072915063 1 13.16971444 -9.366923857 1.004970059 0.997276959 1.13021907 0.095516156 0.115950986 0.817639852 1.429270105 0.080132062 0.019132889 4.30E-10 9.366923857 0.132942111 STVTGERQS(ph)GDGQESTEPVENKVGK ddPTM_HeLa_Curcumin_4h_R1 1 STVTGERQSGDGQESTEPVENKVGK 25 2 O15234;J3KSY7 O15234 CASC3 Protein CASC3 1 0 STVT(0.001)GERQS(0.853)GDGQES(0.125)T(0.021)EPVENKVGK 98.23 5.56E-06 9469700 1223.8 765.53 788.03 732.97 449.8 822.49 522.59 621.59 1711.8 1242.5 TRUE FALSE FALSE 1126.934939 831.6990021 817.235085 729.9371644 444.4364288 651.8963026 537.2524689 811.1099296 1524.019823 1285.676783 0.87653052 0.646895871 0.63564583 0.567745466 0.345682861 0.507045248 0.41787522 0.630881681 1.185383328 1 10.32831228 -7.074063973 0.886255172 0.968226913 0.473810607 0.827200558 0.103913351 0.11761683 0.183928629 0.016811101 0.022247441 8.43E-08 7.074063973 -0.494416307 SVAAEGALLPQTPPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SVAAEGALLPQTPPSPR 17 0 Q86X27;Q86X27-3;H7C2H2 Q86X27 RALGPS2 Ras-specific guanine nucleotide-releasing factor RalGPS2 1 0 SVAAEGALLPQT(0.018)PPS(0.982)PR 154.52 0.00018303 33476000 2523.6 2128.2 2507.1 2899.1 2671.2 2986.4 2411.5 2419 2779.8 2727.2 TRUE FALSE FALSE 2323.854397 2312.152125 2600.015331 2887.104292 2639.347685 2366.986976 2479.1602 3156.541964 2474.862895 2821.969997 0.823486571 0.819339726 0.921347617 1.023081144 0.935285523 0.838771135 0.878521105 1.118559718 0.876998302 1 11.46248693 -6.51318826 24.2826884 0.905272975 0.94898312 0.125147721 0.086828651 974.9977586 2443176.254 0.01578051 0.023097524 3.07E-07 6.51318826 0.043710145 SVAAGCPVLLGKDNPS(ph)PGPSR ddPTM_HeLa_Curcumin_4h_R1 1 SVAAGCPVLLGKDNPSPGPSR 21 1 Q9NQS1 Q9NQS1 AVEN Cell death regulator Aven 1 0 SVAAGCPVLLGKDNPS(0.996)PGPS(0.004)R 121.44 6.18E-06 34142000 821.3 574.12 703.89 560.34 560.93 1339.9 1095 881.41 1373.4 913.68 TRUE FALSE FALSE 756.2932384 623.7443746 729.9767826 558.0214616 554.2412761 1061.989636 1125.722753 1150.147851 1222.741456 945.430312 0.799946044 0.659746537 0.772110618 0.590230136 0.58623176 1.123287061 1.190698816 1.216533717 1.293317382 1 9.88482731 -5.085771237 7.207083632 0.831812204 1.192581992 0.412765736 0.198704603 0.171734875 12.51173899 0.024348824 0.062812251 8.21E-06 5.085771237 0.360769788 SVAAGCPVLLGKDNPSPGPS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SVAAGCPVLLGKDNPSPGPSR 21 1 Q9NQS1 Q9NQS1 AVEN Cell death regulator Aven 1 0 SVAAGCPVLLGKDNPS(0.207)PGPS(0.793)R 76.606 0.00074526 39795000 459.87 496.56 475.8 572.38 564.54 715.07 479.71 380.28 590.39 347.43 TRUE FALSE FALSE 423.4708042 539.4804338 493.4335666 570.0116432 557.8082292 566.7564215 493.1693715 496.2256214 525.6256941 359.5031666 1.177933447 1.500627766 1.372543033 1.585553887 1.551608667 1.576499108 1.371808143 1.380309459 1.462089191 1 8.489860668 -7.476594798 1.171049067 1.050568589 1.492328684 0.21888207 0.156549978 0.124900976 0.341625323 0.020167209 0.021689527 3.34E-08 7.476594798 0.441760095 SVAEGLS(ph)GSLVQEPFQLATEKR ddPTM_HeLa_Curcumin_4h_R1 2 SVAEGLSGSLVQEPFQLATEKR 22 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 0 SVAEGLS(0.5)GS(0.5)LVQEPFQLATEKR;SVAEGLS(0.872)GS(0.128)LVQEPFQLATEKR ; 153.06 8.50E-07 48723000 2204.6 2152.49 2031.52 1828.01 1734.74 3699.5 2584 814.04 2683.3 1689.23 TRUE FALSE FALSE 2030.103584 2338.541644 2106.809918 1820.446179 1714.054358 2932.181998 2656.500086 1062.237049 2388.948703 1747.930617 1.16143259 1.337891574 1.205316675 1.041486522 0.98061922 1.677516241 1.519797216 0.607711221 1.366729709 1 10.7714322 -8.613246263 0.661989878 1.000182144 1.215438007 0 0.300956347 1.542739512 1.351680624 0.165727436 0.065429717 2.44E-09 8.613246263 0.215255863 SVAGGFVYT(ph)Y(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SVAGGFVYTYK 11 0 Q15393;Q15393-3 Q15393 SF3B3 Splicing factor 3B subunit 3 2 0 SVAGGFVY(0.443)T(0.63)Y(0.927)K 71.379 0.0070213 0 1049.6 933.27 988.1 986.35 810.85 1216.9 835.53 907.09 1012.3 982.59 TRUE FALSE FALSE 966.5230525 1013.9377 1024.719855 982.268745 801.1811433 964.5012227 858.9727231 1183.657565 901.2532226 1016.734929 0.950614585 0.997248812 1.007853498 0.966101111 0.787994117 0.948626033 0.844834478 1.164175176 0.886419062 1 9.989727891 -5.981229087 24.9969082 0.980382039 0.924027845 0.011318432 0.097052435 487.3653309 649012.954 0.012579996 0.022800785 1.04E-06 5.981229087 -0.056354194 SVARIGGRLLMRIGDK ddPTM_HeLa_Curcumin_4h_R1 2 SVARIGGRLLMRIGDK 16 3 I3L520;Q9P225-2;Q9P225 I3L520 DNAH2 "Dynein heavy chain 2, axonemal" 0 0 ; ; 70.26 0.01136 19419800 10830.6 7841.6 9040.7 8870.2 9221.2 11538.1 6966.8 3142.7 10829.9 8635.1 FALSE FALSE TRUE 9973.346582 8519.392963 9375.756295 8833.497463 9111.243213 9144.967999 7162.269658 4100.894763 9641.887065 8935.169082 1.116190023 0.953467459 1.049309331 0.988621187 1.019705741 1.023480128 0.801581883 0.45896107 1.079093969 1 13.12527931 -4.309950258 1.640778828 1.041958824 0.279723937 0.937790017 0.04541531 0.173343281 0.475567919 0.007790136 0.202443478 4.90E-05 4.309950258 -0.762234887 down SVAS(ph)NQSEMEFSSLQDMPK ddPTM_HeLa_Curcumin_4h_R1 2 SVASNQSEMEFSSLQDMPK 19 0 Q8N163-2;Q8N163;A0A087X2B6;G3V119;H0YB24 Q8N163-2 CCAR2 Cell cycle and apoptosis regulator protein 2 1 0 S(0.075)VAS(0.735)NQS(0.182)EMEFS(0.001)S(0.007)LQDMPK;S(0.126)VAS(0.74)NQS(0.126)EMEFS(0.001)S(0.008)LQDMPK ; 59.512 0.010082 23069000 6518.7 5096.1 4630.3 4777.9 5117.2 5354.8 3881.9 2536.3 6505.9 5289.6 TRUE FALSE FALSE 6002.738016 5536.584176 4801.902991 4758.130316 5056.180732 4244.154119 3990.815666 3309.606194 5792.219047 5473.413206 1.096708359 1.011541422 0.877314175 0.869316848 0.923771062 0.775412701 0.729127423 0.604669531 1.058246259 1 12.41822506 -4.840099157 0.48488208 1.047180214 0.466597387 0.887135996 0.049812551 0.747701328 0.167671194 0.014340755 0.2229686 1.45E-05 4.840099157 -0.580582827 SVAVS(ph)DEEEVEEEAER ddPTM_HeLa_Curcumin_4h_R1 3 SVAVSDEEEVEEEAER 16 0 Q9Y6X9-2;Q9Y6X9 Q9Y6X9-2 MORC2 MORC family CW-type zinc finger protein 2 1 0 SVAVS(1)DEEEVEEEAER;SVAVS(1)DEEEVEEEAER;S(0.022)VAVS(0.978)DEEEVEEEAER ;; 226.39 1.10E-21 56201000 5658.92 4728.38 4354.06 5007.7 4683.84 5305.36 4069.64 1755.5 5712.45 4405.83 TRUE FALSE FALSE 5211.010511 5137.080098 4515.425294 4986.979464 4627.988267 4204.968532 4183.823146 2290.743869 5085.808527 4558.932265 1.143033107 1.1268165 0.990456763 1.093891985 1.015147407 0.922358194 0.917719962 0.502473767 1.115570101 1 12.15448026 -3.992622626 1.048561734 1.066930652 1.95E-13 0.888400403 0.059421133 0.769039531 0.457810932 0.010326393 1.043034133 0.000101713 3.992622626 -1.066930652 SVCPGGS(ph)SPGSSSGGGR ddPTM_HeLa_Curcumin_4h_R1 2 SVCPGGSSPGSSSGGGR 17 0 Q53LP3 Q53LP3 SOWAHC Ankyrin repeat domain-containing protein SOWAHC 1 0 SVCPGGS(0.489)S(0.489)PGS(0.016)S(0.005)S(0.001)GGGR;S(0.003)VCPGGS(0.482)S(0.482)PGS(0.023)S(0.007)S(0.002)GGGR ; 182.7 5.74E-06 65182300 4932.1 4663.1 4135.6 4221.38 4254.29 4372.7 2702.42 2267.87 4874.5 4380 TRUE FALSE FALSE 4541.719081 5066.157586 4288.868974 4203.913048 4203.56037 3465.75273 2778.242632 2959.333123 4339.779545 4532.204674 1.002099289 1.117813062 0.94630964 0.927564695 0.927486879 0.764694664 0.613000257 0.652956637 0.95754271 1 12.1459973 -5.17960923 1.197502289 1.00597563 0.603341279 0.897026564 0.049268065 0.108770888 0.268662581 0.007083373 0.035639695 6.61E-06 5.17960923 -0.402634351 VSPT(ph)PEPS(ph)PPATEK ddPTM_HeLa_Curcumin_4h_R1 3 VSPTPEPSPPATEK 14 0 Q5JTC6;Q5JTC6-2 Q5JTC6 AMER1 APC membrane recruitment protein 1 2 0 VS(0.063)PT(0.937)PEPS(1)PPATEK;VS(0.013)PT(0.987)PEPS(1)PPATEK;VS(0.012)PT(0.988)PEPS(1)PPATEK ;; 164.53 0.0002564 18313000 14063.9 10990.3 12694.5 12812.5 13324.3 14181.7 9886.4 4545.2 14234.2 11861.7 TRUE FALSE FALSE 12950.72747 11940.25256 13164.96934 12759.48527 13165.41642 11240.25556 10163.78578 5931.010556 12672.74387 12273.89319 1.055144221 0.972817049 1.072599307 1.039563003 1.072635733 0.915785675 0.828081654 0.48322162 1.032495857 1 13.58330531 -4.128462089 1.226380533 1.029585277 0.108235484 0.955685196 0.036022172 0.275077274 0.279380044 0.005504454 0.345170858 7.44E-05 4.128462089 -0.921349793 down SVDS(ph)SGETTYKK ddPTM_HeLa_Curcumin_4h_R1 1 SVDSSGETTYKK 12 1 A6PW58;A2A5X0;A6PW57;Q99755-2;Q99755-4;Q99755-3;Q99755 A6PW58 PIP5K1A Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 1 0 S(0.006)VDS(0.892)S(0.102)GETTYKK 110.8 0.0084137 3503500 695.42 701.51 820.79 802.48 936.52 962.94 928.06 765.15 866.48 928.28 TRUE FALSE FALSE 640.3767732 762.1453985 851.2091994 799.1595504 925.3526107 763.2153894 954.0988659 998.4407127 771.4293118 960.5376609 0.666685752 0.793457071 0.886179932 0.831991897 0.963369421 0.79457102 0.993296676 1.039460245 0.8031224 1 9.90769837 -4.162390044 0.934985245 0.84044214 1.200583394 0.347563824 0.091413507 2.971382637 1.729846845 0.02024246 1.129969865 6.88E-05 4.162390044 0.360141254 SVDVILDDDLVDK ddPTM_HeLa_Curcumin_4h_R1 2 SVDVILDDDLVDK 13 0 P25205;P25205-2;J3KQ69;A0A499FHX9 P25205 MCM3 DNA replication licensing factor MCM3 0 0 ; ; 195.25 3.65E-05 9188800 5492.3 4833.3 5618 5060.7 5253.9 5554.9 4415.9 4162.7 4806.5 4225.7 FALSE FALSE TRUE 5057.57866 5251.068915 5826.208022 5039.760164 5191.250674 4402.751123 4539.798269 5431.888067 4279.238975 4372.54276 1.156667627 1.200918825 1.332453069 1.152592539 1.187238401 1.006908649 1.038251315 1.242272143 0.978661436 1 12.09425678 -8.960020346 0.900948158 1.005162792 1.160656621 0.376143589 0.088832415 0.550812095 0.850908724 0.051591466 0.018458879 1.10E-09 8.960020346 0.155493829 SVDVILDDDLVDKAKPGDR ddPTM_HeLa_Curcumin_4h_R1 1 SVDVILDDDLVDKAKPGDR 19 2 P25205;P25205-2;J3KQ69;A0A499FHX9 P25205 MCM3 DNA replication licensing factor MCM3 0 0 48.547 0.018574 11104000 2407.9 1540.9 1849.2 1935.9 1473.6 2473.9 1973.6 1887.1 2781.7 2394.5 FALSE FALSE TRUE 2217.312174 1674.08853 1917.732979 1927.889759 1456.028282 1960.785253 2028.973904 2462.468103 2476.554469 2477.708697 0.894904303 0.675659948 0.77399453 0.778093793 0.587651117 0.791370372 0.818891223 0.993848916 0.999534155 1 11.27479087 -7.612738987 2.103183269 0.962925322 0.770032021 0.428171736 0.10108179 0.210096107 1.920608293 0.020094763 0.020900107 2.44E-08 7.612738987 -0.192893301 AEGDSAGTAGT(ph)PGGTPAGDKVASWELR ddPTM_HeLa_Curcumin_4h_R1 1 AEGDSAGTAGTPGGTPAGDKVASWELR 27 1 J3KMX2;B9EGA3;Q92925-3;Q92925-2;Q92925 J3KMX2 SMARCD2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 1 0 AEGDSAGT(0.015)AGT(0.984)PGGTPAGDKVASWELR 125.79 1.17E-08 9467300 2362.5 1700.5 2008.3 2169.4 1947.4 2986.3 2655.9 3597 2101.5 1674.6 TRUE FALSE FALSE 2175.505632 1847.483643 2082.729365 2160.423598 1924.178527 2366.907717 2730.417406 4693.708741 1870.970708 1732.792225 1.25549134 1.066188788 1.201949855 1.246787449 1.110449654 1.365950102 1.57573272 2.708754502 1.079743249 1 10.75888296 -2.915725047 0.938422999 1.128430617 19.32412879 0.968728183 0.08427543 3.020362409 0.268427838 0.016476815 98.02758084 0.001214157 2.915725047 18.19569817 up SVEAAAELS(ph)AK ddPTM_HeLa_Curcumin_4h_R1 2 SVEAAAELSAK 11 0 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 1 0 SVEAAAELS(1)AK;SVEAAAELS(1)AK ; 131.69 0.0025916 13796100 4616.9 4322.3 4701.6 4729.9 4628.7 5169.4 4636.1 5409.8 5465.5 4482.1 TRUE FALSE FALSE 4251.467493 4695.900352 4875.845432 4710.328927 4573.505776 4097.208169 4766.176489 7059.223116 4865.948324 4637.852641 0.916688783 1.012516075 1.051315298 1.015627121 0.98612572 0.883427846 1.027668806 1.522088704 1.049181313 1 12.17924127 -4.267361724 4.130614351 0.971153114 1.564968963 0.89892415 0.053001746 0.045063665 1.678872522 0.007354032 0.078496342 5.40E-05 4.267361724 0.593815849 SVEAAAELSAK ddPTM_HeLa_Curcumin_4h_R1 2 SVEAAAELSAK 11 0 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 0 0 ; ; 180.07 1.25E-11 12995900 10145.7 7391.8 8248.8 9399.8 9280.8 6593.5 7487.2 7846.7 10117.3 7906.1 FALSE FALSE TRUE 9342.657139 8030.714255 8554.507784 9360.906118 9170.132521 5225.933776 7697.270681 10239.12271 9007.457502 8180.836387 1.142017356 0.981649537 1.04567643 1.144248054 1.120928483 0.638801894 0.940890432 1.251598519 1.101043595 1 12.99803263 SVEAAAELSAK(ac)DLK ddPTM_HeLa_Curcumin_4h_R1 2 SVEAAAELSAKDLK 14 1 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 0 1 ; SVEAAAELSAK(1)DLK;SVEAAAELSAK(1)DLK 235.73 1.78E-37 6913900 3802.75 2988.21 2767.18 3957.05 3124.58 3720.84 3287.41 3852.31 3540.09 2543.11 FALSE TRUE FALSE 3501.758325 3246.497557 2869.734125 3940.676776 3087.321424 2949.095841 3379.645877 5026.861585 3151.750984 2631.482883 1.33071674 1.233714108 1.090538777 1.49751184 1.173224969 1.12069733 1.284312316 1.910277136 1.197709095 1 11.3616603 -1 0.033943002 1.59E-12 3.264088301 0.278186635 0.209316325 917.0315702 2.405473778 70.0674634 188.5825117 0.1 1 3.264088301 IEEEEEVEQELLSHS(ph)WGR ddPTM_HeLa_Curcumin_4h_R1 4 IEEEEEVEQELLSHSWGR 18 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 0 IEEEEEVEQELLSHS(1)WGR;IEEEEEVEQELLSHS(1)WGR;IEEEEEVEQELLS(0.089)HS(0.911)WGR;IEEEEEVEQELLS(0.002)HS(0.998)WGR ;;; 245.63 1.52E-32 20917800 8357 7360.3 7148.6 8031 6981.6 8570.9 6468.7 2131.14 8719.3 7716.5 TRUE FALSE FALSE 7695.534632 7996.491535 7413.533405 7997.76985 6898.34898 6793.198726 6650.194312 2780.914775 7762.814605 7984.647801 0.963791369 1.001483313 0.928473439 1.00164341 0.863951567 0.850782514 0.832872592 0.34828271 0.972217535 1 12.96301306 -4.128156738 1.270546251 0.973007763 7.09E-35 0.922693088 0.051849452 0.344626989 0.378629275 0.007517971 0.471031636 7.44E-05 4.128156738 -0.973007763 down SVEEEEQVWR ddPTM_HeLa_Curcumin_4h_R1 2 SVEEEEQVWR 10 0 A0A087WVV2;Q9P2E9-3;Q9P2E9;F8W7S5;A0A087WU26 A0A087WVV2 RRBP1 Ribosome-binding protein 1 0 0 ; ; 140.17 0.012975 13959400 2499.8 2170.7 2260.5 2713.3 2480.2 2860.7 1626.56 1026.98 3283.4 2519.3 FALSE FALSE TRUE 2301.938192 2358.325636 2344.276119 2702.073084 2450.625235 2267.358573 1672.196896 1340.101474 2923.219235 2606.845487 0.883035916 0.904666443 0.899276973 1.03652982 0.940073068 0.869770987 0.641463755 0.514070159 1.121362677 1 11.34808936 -4.694145909 2.086067952 0.943851775 0.511966672 0.826250999 0.071308006 0.086406338 0.676388068 0.00795463 0.050439601 2.02E-05 4.694145909 -0.431885103 SVEETLR ddPTM_HeLa_Curcumin_4h_R1 1 SVEETLR 7 0 P30048-2;P30048 P30048-2 PRDX3 "Thioredoxin-dependent peroxide reductase, mitochondrial" 0 0 120.62 0.0094705 2850500 2014.7 1689.9 1796.9 2241.3 2103.9 2977.4 2341.5 1736.9 2421.3 2043.3 FALSE FALSE TRUE 1855.234369 1835.967426 1863.494695 2232.026094 2078.812367 2359.853678 2407.196188 2266.472814 2155.689448 2114.304523 0.877467909 0.868355247 0.881374785 1.055678626 0.983213319 1.116137081 1.138528609 1.071970849 1.019573777 1 11.04596747 -5.649657172 1.407074681 0.931898476 1.112005199 0.590639839 0.06002796 0.22778455 0.894054384 0.010230681 0.028268218 2.24E-06 5.649657172 0.180106723 S(ph)RS(ph)PLELEPEAK ddPTM_HeLa_Curcumin_4h_R1 1 SRSPLELEPEAK 12 1 A0A087WTQ7;A0A087WV56;A0A087WW71;A0A087X0X5;Q92466-3;Q92466-2;Q92466-5;Q92466-4;Q92466 A0A087WTQ7 DDB2 DNA damage-binding protein 2 2 0 S(1)RS(1)PLELEPEAK 77.726 0.019725 34845000 4415.3 3498.4 3915.6 4013 4024.9 4270.5 3148.6 1199 4398.6 4015.7 TRUE FALSE FALSE 4065.824346 3800.786107 4060.715581 3996.395269 3976.905696 3384.750162 3236.941242 1564.56958 3916.084585 4155.245276 0.978479988 0.91469597 0.977250514 0.961771208 0.957080854 0.814572892 0.779001245 0.376528815 0.942443664 1 12.02071792 -4.128104676 1.029057069 0.980364172 7.43E-16 0.948272332 0.040576209 0.312208437 0.215089707 0.005709183 0.357304253 7.45E-05 4.128104676 -0.980364172 down SVEST(ph)SPEPSK ddPTM_HeLa_Curcumin_4h_R1 5 SVESTSPEPSK 11 0 P18583-10;P18583-3;P18583-4;P18583-7;P18583;P18583-5;P18583-9;P18583-6;P18583-2;P18583-8 P18583-10 SON Protein SON 1 0 SVES(0.002)T(0.499)S(0.499)PEPSK;SVES(0.001)T(0.5)S(0.5)PEPSK;SVES(0.033)T(0.483)S(0.483)PEPSK;SVES(0.003)T(0.907)S(0.09)PEPSK;SVES(0.001)T(0.998)SPEPSK ;;;; 225.55 6.02E-16 1858438000 43134.9 36243.4 37165 39560 36593.7 42786.6 31182.3 22257.6 41360 36558.5 TRUE FALSE FALSE 39720.72715 39376.118 38542.36759 39396.3112 36157.34403 33912.17686 32057.19142 29043.83978 36822.91148 37828.90515 1.050009959 1.040900281 1.018860246 1.041434084 0.955812596 0.896462023 0.847425832 0.767768447 0.973406746 1 15.2072014 -4.93712252 1.050282361 1.027163529 0.757841297 0.919393884 0.025425071 0.134452403 0.215354109 0.003741217 0.030895152 1.16E-05 4.93712252 -0.269322232 SVETLK ddPTM_HeLa_Curcumin_4h_R1 1 SVETLK 6 0 P14618;H3BU13;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 132.72 0.019789 34805000 4695 5993 4673.5 3829 3473.6 5208.7 4650 3672.7 4051 4460.2 FALSE FALSE TRUE 4323.385796 6511.008216 4846.704021 3813.156613 3432.179589 4128.356906 4780.466485 4792.489323 3606.615435 4615.191618 0.936772761 1.41077744 1.050163118 0.826218482 0.743670008 0.894514735 1.035811052 1.038416109 0.781466022 1 12.17217483 -6.276412461 24.28531045 1.014897928 0.904993715 0.119447674 0.169125862 1063.030074 1724159.524 0.025509159 0.039070386 5.29E-07 6.276412461 -0.109904213 SVFALTNGIYPHK ddPTM_HeLa_Curcumin_4h_R1 1 SVFALTNGIYPHK 13 0 Q02878 Q02878 RPL6 60S ribosomal protein L6 0 0 94.402 0.0039339 3050300 275.12 325.61 261.28 226.29 229.43 446.35 352.05 347.45 227.91 278.05 FALSE FALSE TRUE 253.3439617 353.7542775 270.9632666 225.3536719 226.6941971 353.7719786 361.9275755 453.3859055 202.9088432 287.7122168 0.880546417 1.22954208 0.941785753 0.783260699 0.787919956 1.229603604 1.257949974 1.575831261 0.705249313 1 8.168482672 -4.678745996 1.601024408 0.945182732 1.56650098 0.654229804 0.153863652 0.22829031 0.920644275 0.019877688 0.172497796 2.10E-05 4.678745996 0.621318248 SVFGT(ph)PTLETANK ddPTM_HeLa_Curcumin_4h_R1 3 SVFGTPTLETANK 13 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 SVFGT(0.892)PT(0.032)LET(0.076)ANK;S(0.001)VFGT(0.998)PT(0.001)LETANK;SVFGT(0.499)PT(0.499)LET(0.001)ANK ;; 174.94 0.00061509 96722000 10404.1 8700.6 9267 8483.8 10301.7 15501.2 13600.4 4561.36 9599.4 7110.4 TRUE FALSE FALSE 9580.604507 9452.641095 9610.443172 8448.696284 10178.85896 12286.07639 13981.99062 5952.097666 8546.369837 7357.485871 1.302157378 1.284765103 1.306212929 1.148312947 1.383469725 1.669874275 1.900376143 0.808985266 1.161588345 1 12.84499715 -9.162984253 0.225892073 0.770451328 1.491426396 0.127012482 0.276798468 6.868602215 0.552403612 1.475594942 0.337487161 6.87E-10 9.162984253 0.720975069 SVFLEQMK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 SVFLEQMKK 9 1 Q7L1Q6-2;Q7L1Q6;Q7L1Q6-4;Q7L1Q6-3;H0Y503 Q7L1Q6-2 BZW1 Basic leucine zipper and W2 domain-containing protein 1 0 1 SVFLEQMK(1)K 80.755 0.0086137 0 0 0 64.742 0 146.83 243.47 0 0 194.94 189.99 FALSE TRUE FALSE 0 0 67.14139547 0 145.0791481 192.9715775 0 0 173.5555697 196.5921384 0 0 0.34152635 0 0.737970243 0.98158339 0 0 0.882820499 1 7.61906182 -9.414042662 1.143648494 0.999647095 0.251769837 0.402345004 0.332396564 0.412522973 0.965765916 0.243514877 0.061733586 3.85E-10 9.414042662 -0.747877257 RQEEEQAHAT(ph)SLPPR ddPTM_HeLa_Curcumin_4h_R1 1 RQEEEQAHATSLPPR 15 1 E9PPA1;C9JJ16;C9JCS0;C9JBS2;E9PID2;B5MBY7;B4DXU5;E9PLL4;Q13133-2;Q13133-3;Q13133 E9PPA1 NR1H3 Oxysterols receptor LXR-alpha 1 0 RQEEEQAHAT(0.822)S(0.178)LPPR 82.651 0.0052446 0 591.28 451.31 506.6 651.15 589.42 582.97 467.66 169.04 654.19 615.05 TRUE FALSE FALSE 544.4795641 490.3192254 525.3750417 648.4557138 582.3915515 462.0554506 480.781281 220.5795178 582.4269937 636.4229417 0.855531013 0.77042984 0.825512418 1.01890688 0.915101442 0.726019476 0.755443039 0.346592656 0.915157131 1 9.313842033 -4.124665168 1.091244382 0.914198588 9.20E-14 0.785870263 0.084114544 0.816743733 0.637035943 0.014466698 0.919739945 7.50E-05 4.124665168 -0.914198588 down SVGDES(ph)WEQTQEGDVGALYHEQLALK ddPTM_HeLa_Curcumin_4h_R1 2 SVGDESWEQTQEGDVGALYHEQLALK 26 0 O75691 O75691 UTP20 Small subunit processome component 20 homolog 1 0 S(0.009)VGDES(0.936)WEQT(0.052)QEGDVGALY(0.003)HEQLALK;S(0.001)VGDES(0.989)WEQT(0.009)QEGDVGALYHEQLALK ; 164.64 3.43E-12 20357200 4984.5 4590.9 5589 5083.9 5004.8 5702.4 5146.2 3134.9 5629.3 4964.8 TRUE FALSE FALSE 4589.971565 4987.716939 5796.133257 5062.864169 4945.121029 4519.657961 5290.588522 4090.716579 5011.779874 5137.32643 0.893455307 0.970877947 1.128239238 0.985505639 0.962586492 0.879768499 1.029833045 0.796273438 0.975561888 1 12.32680203 -4.2467009 24.06296368 0.964660098 0.796273237 0.385363691 0.06717709 1477.951511 2412927.922 0.010069952 0.288572275 5.67E-05 4.2467009 -0.168386861 SVGGDS(ph)DTEDMR ddPTM_HeLa_Curcumin_4h_R1 4 SVGGDSDTEDMR 12 0 Q9UK61-3;Q9UK61;Q9UK61-2;A0A087X0F1;Q9UK61-4 Q9UK61-3 FAM208A Protein FAM208A 1 0 S(0.005)VGGDS(0.571)DT(0.424)EDMR;SVGGDS(0.746)DT(0.253)EDMR;SVGGDS(0.977)DT(0.023)EDMR;SVGGDS(0.975)DT(0.025)EDMR ;;; 212.1 6.06E-10 114398000 12962.3 9550.1 10921.2 11874.2 11348.9 11253.2 8668.1 4679.6 11964.6 11011.1 TRUE FALSE FALSE 11936.32028 10375.56809 11325.94928 11825.06771 11213.57178 8919.15947 8911.303557 6106.388498 10652.11331 11393.73491 1.047621379 0.910638011 0.994050623 1.037857016 0.984187527 0.78281262 0.782123126 0.535942652 0.934909703 1 13.47595312 -4.147661705 0.735618574 1.01709973 0.191099573 0.861459496 0.056229242 0.661280578 0.225230049 0.008387206 0.46790119 7.12E-05 4.147661705 -0.826000157 SVGGS(ph)GGGSFGDNLVTR ddPTM_HeLa_Curcumin_4h_R1 1 SVGGSGGGSFGDNLVTR 17 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 0 S(0.079)VGGS(0.538)GGGS(0.383)FGDNLVTR 240.34 2.25E-30 149290000 1608.3 1018 1203.8 1018.2 1252.2 1227.3 2201.4 1283.2 1498.9 996.69 TRUE FALSE FALSE 1481.001358 1105.991384 1248.413887 1013.986958 1237.268333 972.7441455 2263.165359 1674.441773 1334.47442 1031.324903 1.436018226 1.072398601 1.210495241 0.983188668 1.199688215 0.943198542 2.194425202 1.623583187 1.293941818 1 10.01028319 -4.764184756 24.99999994 1.170375106 1.909004256 0.712720964 0.194038664 28.48424753 259396.2767 0.029438964 0.094509419 1.72E-05 4.764184756 0.73862915 SVGGSGGGS(ph)FGDNLVTR ddPTM_HeLa_Curcumin_4h_R1 2 SVGGSGGGSFGDNLVTR 17 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 0 SVGGS(0.05)GGGS(0.949)FGDNLVT(0.001)R;S(0.012)VGGS(0.001)GGGS(0.982)FGDNLVT(0.005)R ; 159.95 0.00014803 167241000 1924.71 1479.16 1574.66 1661.32 1440.05 1994.56 3060.7 1824.36 2227.4 1856.69 TRUE FALSE FALSE 1772.367173 1607.011999 1633.018285 1654.445898 1422.878344 1580.865773 3146.575005 2380.598966 1983.059793 1921.209839 0.922526596 0.836458343 0.849994754 0.861147941 0.740615791 0.822849092 1.637809124 1.239114498 1.032193232 1 10.90779939 -4.768669224 24.99993075 0.914765932 1.438461845 0.760811836 0.123520244 52.45689608 181392.352 0.017238075 0.053296373 1.70E-05 4.768669224 0.523695912 SVGGSGGGSFGDNLVTR ddPTM_HeLa_Curcumin_4h_R1 2 SVGGSGGGSFGDNLVTR 17 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 281.6 1.69E-93 11642600 2294.7 1726.88 1992.73 2069.37 1710.07 2028.16 1683.54 1575.8 2671.6 1783.96 FALSE FALSE TRUE 2113.072074 1876.143812 2066.582327 2060.807495 1689.678532 1607.496754 1730.775601 2056.254166 2378.532164 1845.952477 1.144705565 1.016355424 1.119520872 1.116392497 0.915342379 0.870822393 0.93760572 1.113925841 1.288512133 1 10.8501497 -5.759336075 24.99993834 1.072862144 0.951536928 0.322753022 0.099312318 49.56401899 589103.8629 0.011906842 0.022913737 1.74E-06 5.759336075 -0.121325216 LEPTAPALS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 LEPTAPALSPR 11 0 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 0 LEPTAPALS(1)PR;LEPTAPALS(1)PR ; 168.83 0.00024822 317510000 6181.9 4720 5164.5 5641.3 5437.4 6399.8 4382.3 1592.32 5834.5 4882.2 TRUE FALSE FALSE 5692.596092 5127.975768 5355.900913 5617.957795 5372.562556 5072.409339 4505.255544 2077.811038 5194.469947 5051.856087 1.126832593 1.015067666 1.060184776 1.112058162 1.063482899 1.004068456 0.891802036 0.411296562 1.028229993 1 12.30259783 -4.124608491 1.598156896 1.061294991 2.01E-13 0.960795237 0.038970648 0.248343407 0.45636321 0.007307173 0.451446786 7.51E-05 4.124608491 -1.061294991 down SVGKVEPSSQSPGRS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 SVGKVEPSSQSPGRSPR 17 2 X6RM00;G8JLD3;X6RLX0;Q8IUD2-5;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 0 S(0.036)VGKVEPS(0.098)S(0.073)QS(0.201)PGRS(0.592)PR;S(0.011)VGKVEPS(0.009)S(0.04)QS(0.015)PGRS(0.925)PR;S(0.012)VGKVEPS(0.01)S(0.026)QS(0.095)PGRS(0.857)PR ;; 58.658 0.010856 42258000 12508.2 11814.4 9399.7 10554.8 7137.6 11640 6751 5120.3 14702.4 12278.1 TRUE FALSE FALSE 11518.16277 12835.58409 9748.061151 10511.12703 7052.488782 9225.73279 6940.414891 6681.455899 13089.5835 12704.76306 0.906601935 1.010297007 0.767276108 0.82733751 0.555105888 0.726163309 0.546284481 0.525901653 1.030289462 1 13.63308185 -5.9042268 0.619327044 0.972038372 0.515453308 0.835599845 0.076316429 0.254089731 0.171133983 0.015150353 0.05752648 1.25E-06 5.9042268 -0.456585064 SVLFVCLGNICR ddPTM_HeLa_Curcumin_4h_R1 1 SVLFVCLGNICR 12 0 F2Z2Q9;G5E9R5;D3YTI2;P24666-4;P24666-3;P24666-2;P24666 F2Z2Q9 ACP1 Low molecular weight phosphotyrosine protein phosphatase 0 0 104.05 0.00050773 0 310.34 247.76 305.36 195.57 186.79 277.06 68.351 69.359 191.81 298.97 FALSE FALSE TRUE 285.7762615 269.1752704 316.6769102 194.7607832 184.5626512 219.5946329 70.2687451 90.50623981 170.7689229 309.3591852 0.923768471 0.870105959 1.023654462 0.629561986 0.596596643 0.709837119 0.227142908 0.292560377 0.552008575 1 8.27313906 -4.921391184 0.51579674 0.978437438 4.47E-12 0.57347477 0.172539044 0.592575033 0.160163201 0.022202536 0.308038294 1.20E-05 4.921391184 -0.978437438 SVLGQNY(ph)DIT(ph)MEDISLMGKMY(ph)LK ddPTM_HeLa_Curcumin_4h_R1 1 SVLGQNYDITMEDISLMGKMYLK 23 1 G3V435;G3V3A5 G3V435 TTC6 3 0 S(0.218)VLGQNY(0.788)DIT(0.972)MEDIS(0.133)LMGKMY(0.889)LK 40.369 0.013855 7312600 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 SVLISLK(ac)QAPLVH ddPTM_HeLa_Curcumin_4h_R1 1 SVLISLKQAPLVH 13 1 P09496-2;P09496-4;P09496-3;P09496;P09496-5;C9J8P9 P09496-2 CLTA Clathrin light chain A 0 1 SVLISLK(1)QAPLVH 150.09 0.00023239 2796000 927.71 1059.8 849.05 616.19 829.85 1790.3 1010 1179.1 833.82 712.05 FALSE TRUE FALSE 854.2807746 1151.40439 880.5165399 613.640369 819.9545807 1418.971599 1038.337882 1538.602162 742.3520321 736.7936845 1.159457244 1.562722936 1.195065265 0.832852374 1.112868633 1.925873727 1.409265448 2.088240161 1.007543968 1 9.525116885 -1 0.397440245 1.076002797 16.60372187 0.558394503 0.261196946 34.22274948 0.405721558 0.063995391 419.9028954 0.1 1 15.52771907 APPPESWNTVSGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 APPPESWNTVSGKK 14 1 Q01804-5;Q01804-3;Q01804;D6RI06 Q01804-5 OTUD4 OTU domain-containing protein 4 0 1 ; APPPESWNTVSGK(1)K;APPPESWNTVSGK(1)K 117.27 0.00017447 8249700 2693.2 2455.02 2370.7 2647.35 2618.62 3435.62 2857.03 3574.6 3201.36 1927.35 FALSE TRUE FALSE 2480.030378 2667.220989 2458.560227 2636.395967 2587.394667 2723.033685 2937.190572 4664.479085 2850.178817 1994.325269 1.243543577 1.337405202 1.232777955 1.321948836 1.29737847 1.365390955 1.472774085 2.338875788 1.429144414 1 10.96168501 -1 0.713382486 1.154167473 158.4323766 0.831891375 0.13731742 72.88495201 0.342468291 0.022386446 18348.77252 0.1 1 157.2782091 up SVNEILGLAES(ph)SPNEPK ddPTM_HeLa_Curcumin_4h_R1 1 SVNEILGLAESSPNEPK 17 0 Q9H8G2;Q9H8G2-2 Q9H8G2 CAAP1 Caspase activity and apoptosis inhibitor 1 1 0 SVNEILGLAES(0.571)S(0.429)PNEPK 72.771 0.0077952 3609700 1907.1 1625.4 1475.3 1858.9 2011.7 2322.8 2052.9 1839.8 2039.5 1962.9 TRUE FALSE FALSE 1756.151023 1765.892333 1529.975916 1851.208364 1987.711791 1841.025097 2110.498849 2400.746551 1815.771953 2031.110629 0.864625982 0.869422034 0.753270597 0.911426654 0.978632952 0.906413009 1.039086113 1.181987094 0.893979839 1 10.98805311 -4.374564232 1.746701991 0.915514956 1.24021177 0.646875874 0.065920999 0.441009849 1.574354006 0.01154696 0.219367391 4.22E-05 4.374564232 0.324696814 SVNEILGLAESS(ph)PNEPK ddPTM_HeLa_Curcumin_4h_R1 2 SVNEILGLAESSPNEPK 17 0 Q9H8G2;Q9H8G2-2 Q9H8G2 CAAP1 Caspase activity and apoptosis inhibitor 1 1 0 SVNEILGLAES(0.216)S(0.784)PNEPK;SVNEILGLAES(0.468)S(0.532)PNEPK ; 248.01 3.97E-31 20791700 3298 2802.6 3038.4 3439.8 3199.3 4655.9 2970.4 3427.2 3428.8 3202.1 TRUE FALSE FALSE 3036.95982 3044.844256 3151.005777 3425.567019 3161.150437 3690.213857 3053.74143 4472.137503 3052.669218 3313.372737 0.916576571 0.918956151 0.95099647 1.033861051 0.954058202 1.113733392 0.921641382 1.349723638 0.921317781 1 11.69408479 -2.283961536 1.582657796 0.966668595 199.9999997 0.746782149 0.06485428 267.910709 1.618448657 0.009050144 192725.3682 0.005200421 2.283961536 199.0333311 SVNELIYK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 SVNELIYKR 9 1 P18124;A8MUD9 P18124 RPL7 60S ribosomal protein L7 0 1 SVNELIYK(1)R 83.883 0.011643 7197400 7833.2 6205.5 6019.4 6620 6332.5 8378.9 6069.4 6364.2 8964.9 7524.3 FALSE TRUE FALSE 7213.193954 6741.875769 6242.484259 6592.608194 6256.989073 6641.02169 6239.691029 8304.615283 7981.472899 7785.768865 0.926458784 0.865922928 0.801781348 0.84675108 0.803644339 0.852969284 0.801422587 1.066640357 1.025136122 1 12.9266238 -7.744038081 1.099580569 0.981328025 0.854556232 0.360455145 0.07543523 0.336017556 0.848704658 0.017020637 0.015910971 1.80E-08 7.744038081 -0.126771793 SVNFSLT(ph)PNEIK ddPTM_HeLa_Curcumin_4h_R1 2 SVNFSLTPNEIK 12 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 SVNFS(0.3)LT(0.7)PNEIK;SVNFS(0.428)LT(0.572)PNEIK ; 129.77 0.0078614 174160000 8512.4 6939 7256.9 7489.7 8225.7 8873.8 4610.7 3807.7 8522.2 7211.1 TRUE FALSE FALSE 7838.634558 7538.77624 7525.847098 7458.709606 8127.6139 7033.273852 4740.063833 4968.650202 7587.335981 7461.685188 1.050517994 1.010331587 1.00859885 0.999601218 1.089246423 0.942585177 0.635253795 0.665888479 1.016839466 1 12.86528578 -4.834939998 3.98120144 1.023790539 0.646217466 0.963420073 0.028700047 0.025876787 0.78762174 0.004164044 0.014375309 1.46E-05 4.834939998 -0.377573073 SVNGGPGS(ph)PDLAR ddPTM_HeLa_Curcumin_4h_R1 1 SVNGGPGSPDLAR 13 0 A0A087X2C4;H0YAH0;O60245;O60245-2 A0A087X2C4 PCDH7 Protocadherin-7 1 0 SVNGGPGS(1)PDLAR 173.19 0.00020597 74755000 6645.2 3785.8 3823.2 5647 5414.7 13296 4737.7 2016 7289.6 4092.6 TRUE FALSE FALSE 6119.225408 4113.027683 3964.891155 5623.63421 5350.133239 10538.25972 4870.627111 2630.669119 6489.949118 4234.817545 1.444979705 0.971240824 0.936260208 1.327951948 1.263368063 2.488480226 1.150138597 0.621200109 1.532521543 1 12.0480841 -5.771386504 3.357234147 1.176277964 1.450858944 0.032028498 0.471465806 0.558466523 13.16120253 0.069760848 0.139528125 1.69E-06 5.771386504 0.274580979 ASQGLLSSIENSES(ph)DSSEAKEEGSR ddPTM_HeLa_Curcumin_4h_R1 1 ASQGLLSSIENSESDSSEAKEEGSR 25 1 Q5UIP0-2;Q5UIP0 Q5UIP0-2 RIF1 Telomere-associated protein RIF1 1 0 ASQGLLSSIENS(0.007)ES(0.82)DS(0.143)S(0.03)EAKEEGSR 137.51 5.85E-08 27419000 2134.5 1453.4 1992.3 2413.7 1827.8 1894 1487.6 617.92 2300.1 1878.2 TRUE FALSE FALSE 1965.552073 1579.02542 2066.136391 2403.712749 1806.004679 1501.16305 1529.338052 806.3209634 2047.784785 1943.46731 1.011363588 0.812478508 1.063118674 1.236816661 0.929269388 0.77241487 0.786912157 0.414887845 1.05367596 1 10.92441713 -4.124084627 0.947038217 1.007540937 0.002483619 0.733433927 0.110533333 0.977917571 0.55929723 0.017003517 1.067311903 7.51E-05 4.124084627 -1.005057318 down SVNVSLTQEELDS(ph)GLDELSVR ddPTM_HeLa_Curcumin_4h_R1 1 SVNVSLTQEELDSGLDELSVR 21 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 SVNVSLTQEELDS(1)GLDELSVR 174.5 2.32E-09 1233800 372.56 365.59 239.91 362.06 479.52 563.34 160.74 134.27 382.6 262.62 TRUE FALSE FALSE 343.0714829 397.1899706 248.8012756 360.5618917 473.8020372 446.4969338 165.2499318 175.2083049 340.6297372 271.7460255 1.262471023 1.461622005 0.915565463 1.326834095 1.743547257 1.643067026 0.608104319 0.644750202 1.253485627 1 8.086115124 -9.275917048 1.053982637 1.002542901 1.218545911 0 0.371625084 1.565226733 3.170545424 0.243419362 0.069111532 5.30E-10 9.275917048 0.21600301 SVPAGLTLQSVS(ph)PQSLQGK ddPTM_HeLa_Curcumin_4h_R1 1 SVPAGLTLQSVSPQSLQGK 19 0 A0JP02;B4DJX4;Q9HAU0-8;Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;Q9HAU0-5;H0YG48;Q9HAU0-3 A0JP02 PLEKHA5 Pleckstrin homology domain-containing family A member 5 1 0 SVPAGLT(0.121)LQS(0.151)VS(0.694)PQS(0.035)LQGK 177.02 4.38E-07 21352000 947.41 926.98 814.9 863.64 919.69 1260.8 994.26 552.82 854.34 764.09 TRUE FALSE FALSE 872.4214988 1007.104021 845.1009109 860.0664865 908.7232974 999.2958679 1022.15626 721.3722731 760.6210395 790.6420706 1.103434198 1.273779954 1.068879259 1.087807642 1.149348525 1.263904243 1.292817948 0.912387919 0.962029555 1 9.626880914 -8.370409158 0.715127381 1.006137721 1.156271352 0.247263698 0.109995156 0.684760976 0.744684264 0.04818276 0.025118408 4.26E-09 8.370409158 0.150133631 SVPGTTSSPLVGDIS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SVPGTTSSPLVGDISPK 17 0 Q9UQR0;H0Y6S1;B4DRC2;Q9UQR0-2 Q9UQR0 SCML2 Sex comb on midleg-like protein 2 1 0 SVPGTTS(0.001)S(0.021)PLVGDIS(0.978)PK;SVPGTTSS(0.001)PLVGDIS(0.999)PK ; 216.53 1.66E-15 102805000 6246.6 4783.8 5614 5776 5638.7 6587.9 4927.2 6592.7 6606.2 5876.6 TRUE FALSE FALSE 5752.175019 5197.290356 5822.059779 5752.100442 5571.462185 5221.495279 5065.443971 8602.783881 5881.516388 6080.811413 0.945955174 0.854703427 0.957447844 0.94594291 0.916236635 0.858683969 0.83302106 1.414742753 0.967225587 1 12.57004813 -4.253019251 24.87328334 0.944305257 1.414743006 0.869268118 0.056865553 307.0804906 907102.236 0.009082858 0.139164773 5.58E-05 4.253019251 0.470437749 SVPHLQK ddPTM_HeLa_Curcumin_4h_R1 2 SVPHLQK 7 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YNP5;H0YN28;H0YL33;P07355-2 P07355;P07355-2 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 0 ; ; 89.55 0.0094284 41405000 17895.4 12603 15252.5 15507.9 18414.5 26188 19154 19876.4 21600 13952.6 FALSE FALSE TRUE 16478.96021 13692.34716 15817.77107 15443.73242 18194.91911 20756.3136 19691.40969 25936.62286 19230.53404 14437.45181 1.141403651 0.948390848 1.095606848 1.069699322 1.260258344 1.437671541 1.363911717 1.796482038 1.331989488 1 13.81752851 -1 0.422773239 1.044823621 15.03029196 0.747010968 0.120607831 16.15433084 0.18376147 0.019529856 193.352369 0.1 1 13.98546834 SVPTSTVFYPSDGVATEK ddPTM_HeLa_Curcumin_4h_R1 1 SVPTSTVFYPSDGVATEK 18 0 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 0 267.77 6.69E-77 1856800 613.7 511.23 562.56 444.78 382.51 618.49 590.07 663.01 583.45 550.79 FALSE FALSE TRUE 565.1249974 555.4184432 583.4089685 442.9396182 377.9488181 490.2082022 606.6257761 865.1586969 519.4469947 569.9299115 0.99156929 0.974538153 1.023650376 0.777182614 0.663149644 0.860120152 1.064386627 1.518008933 0.911422588 1 9.154640701 -4.290518413 3.238917175 0.949862228 1.58032694 0.710905766 0.11527093 0.148440659 2.512285689 0.018199731 0.224914402 5.12E-05 4.290518413 0.630464711 SVPVNNLPERS(ph)PTDS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 SVPVNNLPERSPTDSPR 17 1 P49454 P49454 CENPF Centromere protein F 2 0 SVPVNNLPERS(0.938)PT(0.064)DS(0.999)PR;SVPVNNLPERS(0.983)PT(0.16)DS(0.856)PR ; 144.3 0.0011814 19586700 2196.47 2001.54 1813.55 2086.5 2043.5 3333.8 2927.4 1234.5 2243.75 1933.66 TRUE FALSE FALSE 2022.617082 2174.544199 1880.761758 2077.866616 2019.132597 2642.3323 3009.534965 1610.893367 1997.616239 2000.854541 1.010876623 1.086807739 0.939979254 1.038489592 1.009135125 1.320601896 1.504124814 0.805102687 0.99838154 1 10.96640057 -5.274858359 23.82617767 1.009313276 1.239361291 0.223287498 0.166479091 350.184383 621772.9954 0.021255774 0.047817952 5.31E-06 5.274858359 0.230048015 SVPVNNLPERS(ph)PTDSPR ddPTM_HeLa_Curcumin_4h_R1 2 SVPVNNLPERSPTDSPR 17 1 P49454 P49454 CENPF Centromere protein F 1 0 SVPVNNLPERS(0.648)PT(0.333)DS(0.019)PR;SVPVNNLPERS(0.872)PT(0.128)DSPR ; 127.05 0.00015288 42536000 3529 3155.4 3116.8 3338.2 3059.27 3961.7 2590.52 2794.5 3450.6 3727 TRUE FALSE FALSE 3249.675926 3428.138716 3232.31135 3324.387413 3022.790203 3139.998762 2663.203019 3646.530186 3072.077813 3856.512973 0.84264618 0.888921868 0.838143518 0.862018989 0.783814349 0.814206716 0.690572815 0.945551127 0.796594705 1 11.91308125 -10.36970552 0.247953376 1.187837545 0.796454583 0 0.089406137 5.444859313 0.279703856 0.659540636 0.045061425 4.27E-11 10.36970552 -0.391382963 SVPVNNLPERSPT(ph)DSPR ddPTM_HeLa_Curcumin_4h_R1 1 SVPVNNLPERSPTDSPR 17 1 P49454 P49454 CENPF Centromere protein F 1 0 SVPVNNLPERS(0.379)PT(0.589)DS(0.031)PR 95.414 0.0024951 52361000 2166.9 1440.6 1967.4 2154.7 1912.1 2698.5 1736 2071 2438.3 1861.1 TRUE FALSE FALSE 1995.387578 1565.119045 2040.313575 2145.784422 1889.299456 2138.800682 1784.707488 2702.438366 2170.82459 1925.773086 1.036148855 0.812722462 1.059477666 1.114245722 0.981060266 1.110619261 0.926748588 1.403300516 1.127248379 1 10.91122201 -4.253687447 24.95215847 1.012390444 1.40330071 0.611549345 0.09183374 411.6607471 1325034.237 0.010800106 0.157127286 5.58E-05 4.253687447 0.390910266 SVQEGENPDDGVRGS(ph)PPEDYR ddPTM_HeLa_Curcumin_4h_R1 1 SVQEGENPDDGVRGSPPEDYR 21 1 H7C5M1;Q5TCT4;A2A2V2;P42696-2;P42696 H7C5M1 RBM34 RNA-binding protein 34 1 0 SVQEGENPDDGVRGS(0.996)PPEDY(0.004)R 62.792 0.0057257 0 773.99 694.03 936.83 894 758.3 666.35 523.32 801.42 1127.6 834.44 TRUE FALSE FALSE 712.7278748 754.0188607 971.5497439 890.3008649 749.2577678 528.1414987 538.0029508 1045.769269 1003.905101 863.4367279 0.825454665 0.873276334 1.125212436 1.031113035 0.867762215 0.611673654 0.623094818 1.211170703 1.162685196 1 9.753946652 -5.520087498 24.7882138 0.936887073 0.786695684 0.11634126 0.187976996 154.2651153 1369977.401 0.0251733 0.051099466 3.02E-06 5.520087498 -0.150191389 GYYSPYS(ph)VSGSGSTAGSRT(ph)GS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 GYYSPYSVSGSGSTAGSRTGSR 22 1 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 3 0 GYYS(0.005)PY(0.003)S(0.607)VS(0.301)GS(0.197)GS(0.227)T(0.312)AGS(0.456)RT(0.443)GS(0.448)R 59.893 0.008211 12605000 2523.4 2477.6 2822.9 3008.8 3071.4 4687.2 4067.7 5284.2 3080.3 3293.4 TRUE FALSE FALSE 2323.670227 2691.752704 2927.519157 2996.350383 3034.775561 3715.021884 4181.828714 6895.328255 2742.398797 3407.845405 0.681859049 0.78986937 0.859052806 0.879250678 0.890526183 1.090138032 1.227118081 2.023368855 0.804730987 1 11.73464417 -2.824132476 0.826769174 0.841815554 13.14635252 0.950380291 0.081263494 4.502384671 0.33947231 0.019170595 85.91600973 0.001499227 2.824132476 12.30453696 up SVS(ph)EESANSLVSVGVEAK ddPTM_HeLa_Curcumin_4h_R1 1 SVSEESANSLVSVGVEAK 18 0 Q8NEZ4;Q8NEZ4-3;H0YMU7;C9J4Z5 Q8NEZ4 KMT2C Histone-lysine N-methyltransferase 2C 1 0 S(0.004)VS(0.996)EESANSLVSVGVEAK 244.18 2.54E-71 0 1343.2 899.09 1416.3 1120.2 1172.6 1879.8 1328.4 852.38 1372.6 1021.4 TRUE FALSE FALSE 1236.884303 976.8033333 1468.789324 1115.564909 1158.617511 1489.90829 1365.671329 1112.266738 1222.029214 1056.893574 1.170301659 0.924221092 1.389723015 1.055513002 1.096248042 1.409705127 1.292155958 1.052392375 1.156246233 1 10.04561439 -13.52287819 0.12249671 0.3557076 1.282288327 0.046549999 0.15132655 102.2901052 0.900948445 16.18620449 0.617610932 3.00E-14 13.52287819 0.926580727 SVS(ph)EINSDDELSGK ddPTM_HeLa_Curcumin_4h_R1 1 SVSEINSDDELSGK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 0 S(0.001)VS(0.999)EINSDDELSGK 288.45 6.61E-77 15566000 4121.1 3669.1 3520.3 3865.9 3720 3975.4 3121.9 1609.2 3865.2 3407.8 TRUE FALSE FALSE 3794.910586 3986.240655 3650.765415 3849.90393 3675.64143 3150.857228 3209.492112 2099.837672 3441.19723 3526.220796 1.076197665 1.130456907 1.035319575 1.091793212 1.042374157 0.893550747 0.910178998 0.595492396 0.97588819 1 11.7839071 -3.846525069 0.940674826 1.048278351 6.75E-17 0.867742593 0.052915679 0.988394161 0.390318065 0.008150873 1.270437454 0.000142389 3.846525069 -1.048278351 YEAVS(ph)PERLELER ddPTM_HeLa_Curcumin_4h_R1 1 YEAVSPERLELER 13 1 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 0 YEAVS(1)PERLELER 78.508 0.010292 51783000 3389.9 2438.7 2673.5 2628.6 2819.2 3144.8 2180.4 854.54 3543.1 2762.4 TRUE FALSE FALSE 3121.585838 2649.490361 2772.582262 2617.72355 2785.582881 2492.533031 2241.576156 1115.085312 3154.430794 2858.393194 1.092077131 0.926915991 0.969979311 0.915802471 0.974527538 0.872004956 0.784208471 0.39010914 1.103567837 1 11.48098867 -4.123953578 0.899780786 1.022561336 1.83E-30 0.896471355 0.06221302 0.604351458 0.309356386 0.010296601 0.640917036 7.52E-05 4.123953578 -1.022561336 down SVS(ph)GSPEPAAK ddPTM_HeLa_Curcumin_4h_R1 2 SVSGSPEPAAK 11 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 S(0.006)VS(0.497)GS(0.497)PEPAAK;S(0.077)VS(0.461)GS(0.461)PEPAAK ; 165.35 0.00026931 135933000 13892.1 11416.9 11411.7 10876.9 10661.7 14345.8 11523.2 14661.6 13398.9 9877.3 TRUE FALSE FALSE 12792.52563 12403.72596 11834.62764 10831.89427 10534.56619 11370.31937 11846.50998 19131.85435 11929.07419 10220.53544 1.251649261 1.213608234 1.157926384 1.059816713 1.03072547 1.112497426 1.159088978 1.871903332 1.167167245 1 13.31918316 -4.26085865 4.843023322 1.120302201 1.912932251 0.899424631 0.074694245 0.052713486 3.583398087 0.014244319 0.140160788 5.48E-05 4.26085865 0.792630049 SQDSYPGS(ph)PSLSPR ddPTM_HeLa_Curcumin_4h_R1 2 SQDSYPGSPSLSPR 14 0 A0A0D9SEU5;R4GMX8;Q6VN20-2;Q6VN20-3;Q6VN20 A0A0D9SEU5 RANBP10 Ran-binding protein 10 1 0 SQDSYPGS(0.922)PS(0.078)LSPR;SQDSYPGS(0.977)PS(0.023)LSPR ; 284.53 1.00E-63 65310000 5780.9 4521.7 4854 4966.8 4887.8 4966.1 3961.7 1400.94 5260.7 4234.4 TRUE FALSE FALSE 5323.335665 4912.5356 5033.89351 4946.248698 4829.516177 3936.074881 4072.85464 1828.080157 4683.614372 4381.545085 1.214944857 1.121187961 1.148885476 1.128882301 1.102240439 0.898330339 0.929547582 0.41722272 1.068941271 1 12.09722399 -4.121989585 1.137070592 1.109374326 1.48E-14 0.885048885 0.073480388 0.626284684 0.532746513 0.013821989 0.888755953 7.55E-05 4.121989585 -1.109374326 down SNS(ph)LPHSAVSNAGSK ddPTM_HeLa_Curcumin_4h_R1 2 SNSLPHSAVSNAGSK 15 0 A0A088AWN2;Q8TBZ3-4;Q8TBZ3-5;Q8TBZ3-6;Q8TBZ3;Q8TBZ3-2;Q8TBZ3-7 A0A088AWN2 WDR20 WD repeat-containing protein 20 1 0 SNS(0.5)LPHS(0.5)AVSNAGSK;S(0.007)NS(0.953)LPHS(0.041)AVSNAGSK ; 168.68 0.00019194 8701600 2698.7 1826.98 1855.44 1906.52 2479.5 4444.3 3298.7 4495.8 2759.4 1908.45 TRUE FALSE FALSE 2485.095047 1984.89601 1924.204239 1898.631325 2449.933582 3522.502082 3391.252644 5866.548724 2456.700724 1974.768495 1.258423483 1.005128457 0.974394843 0.961445015 1.240618122 1.783754445 1.717291243 2.970752641 1.244044924 1 10.94746782 -2.756381414 0.702808687 1.089697112 16.79738424 0.922164036 0.164390287 3.730724467 0.245368296 0.028645642 74.86074262 0.001752341 2.756381414 15.70768712 up VASPSQGQVGSSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 VASPSQGQVGSSSPK 15 0 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 0 VASPSQGQVGS(0.005)S(0.337)S(0.658)PK;VASPSQGQVGS(0.034)S(0.309)S(0.657)PK ; 157.07 0.0003541 6842600 2727.3 2511.3 2745.6 3563.3 2995 3095.7 2281.2 813.11 3284.1 2649.9 TRUE FALSE FALSE 2511.431327 2728.365582 2847.354351 3548.556009 2959.286581 2453.616924 2345.204332 1061.023496 2923.842446 2741.983828 0.915917629 0.995033433 1.038428572 1.294156433 1.079250195 0.894832748 0.855294735 0.386954688 1.066323739 1 11.42100435 -4.121545708 1.630784038 0.998167015 1.25E-06 0.766545511 0.107080354 0.613586306 1.174007315 0.01709654 1.06953226 7.56E-05 4.121545708 -0.998165766 down SVS(ph)PSPVPLLFQPDQNAPPIR ddPTM_HeLa_Curcumin_4h_R1 2 SVSPSPVPLLFQPDQNAPPIR 21 0 Q02241-2;Q02241-3 Q02241-2 KIF23 Kinesin-like protein KIF23 1 0 S(0.185)VS(0.604)PS(0.211)PVPLLFQPDQNAPPIR;S(0.161)VS(0.795)PS(0.044)PVPLLFQPDQNAPPIR ; 120.44 6.53E-06 82856000 2652.7 1570.81 2067.88 2643.7 2248.7 2931.9 1990.66 932.89 3168.4 2259.58 TRUE FALSE FALSE 2442.735996 1706.583817 2144.517452 2632.76107 2221.885721 2323.790891 2046.512562 1217.323867 2820.834447 2338.100237 1.044752469 0.729901905 0.917205096 1.126025749 0.950295324 0.993879926 0.875288634 0.520646569 1.206464292 1 11.19112107 -4.227465055 2.038659523 0.994909015 0.356600204 0.589010267 0.119553343 0.371034786 1.535736232 0.01444846 0.450807492 5.92E-05 4.227465055 -0.638308811 SVS(ph)PTFLNPSDENLK ddPTM_HeLa_Curcumin_4h_R1 1 SVSPTFLNPSDENLK 15 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 0 S(0.027)VS(0.486)PT(0.486)FLNPSDENLK 142.95 0.00051176 46605000 4675.8 3571.3 4294.6 4017.3 4339.7 4288.4 2284.1 1705.9 4398.1 4046 TRUE FALSE FALSE 4305.705496 3879.987259 4453.761654 4000.677477 4287.951912 3398.9375 2348.185699 2226.021057 3915.639434 4186.598199 1.02844966 0.926763705 1.063813971 0.955591458 1.024209085 0.811861406 0.560881553 0.531701623 0.935279491 1 12.03156275 -4.922120497 2.220621701 1.007720466 0.524373691 0.939992405 0.044474409 0.037817775 0.362216216 0.005064643 0.021294441 1.20E-05 4.922120497 -0.483346775 SVS(ph)PTTEMVSNESVDYR ddPTM_HeLa_Curcumin_4h_R1 1 SVSPTTEMVSNESVDYR 17 0 P08581;P08581-2 P08581 MET Hepatocyte growth factor receptor 1 0 S(0.031)VS(0.922)PT(0.047)T(0.001)EMVSNESVDYR 190.55 2.02E-07 19545000 1719.1 1047.8 1063.1 1486.9 940.41 1364.3 680.41 864.88 1868.6 1231.4 TRUE FALSE FALSE 1583.031421 1138.367163 1102.499421 1480.747602 929.196225 1081.328801 699.5004734 1128.577931 1663.619255 1274.191058 1.242381518 0.893403823 0.865254401 1.162107984 0.729244032 0.848639452 0.548976128 0.885721119 1.30562779 1 10.3153659 -5.847655423 0.82952035 1.101017717 0.706114965 0.467820886 0.162100967 0.432046558 0.555785332 0.028646117 0.094814658 1.42E-06 5.847655423 -0.394902752 SVS(ph)PVQDLDDDTPPS(ph)PAHSDMPYDAR ddPTM_HeLa_Curcumin_4h_R1 2 SVSPVQDLDDDTPPSPAHSDMPYDAR 26 0 G3V3A7;O00409-2;O00409 G3V3A7 FOXN3 Forkhead box protein N3 2 0 S(0.205)VS(0.794)PVQDLDDDTPPS(0.891)PAHS(0.073)DMPY(0.035)DAR;S(0.187)VS(0.812)PVQDLDDDT(0.001)PPS(0.998)PAHS(0.001)DMPY(0.001)DAR ; 90.164 3.65E-05 9301300 1019.28 1150.65 1054.06 1073.77 892.27 1157.94 736.9 586.13 1256.96 1282.86 TRUE FALSE FALSE 938.6029125 1250.107059 1093.124391 1069.327024 881.630263 917.7701913 757.5754307 764.8383388 1119.074633 1327.43929 0.707077845 0.941743301 0.823483529 0.805556256 0.664158632 0.691383929 0.570704391 0.576175758 0.843032628 1 10.37443017 -8.504326502 0.05555312 1.705799927 6.44E-24 0.605459686 0.086557024 33.78704318 0.754748383 13.14661253 9.884455572 3.13E-09 8.504326502 -1.705799927 SVS(ph)PVQDLDDDTPPSPAHSDMPYDAR ddPTM_HeLa_Curcumin_4h_R1 1 SVSPVQDLDDDTPPSPAHSDMPYDAR 26 0 G3V3A7;O00409-2;O00409 G3V3A7 FOXN3 Forkhead box protein N3 1 0 S(0.462)VS(0.525)PVQDLDDDT(0.013)PPSPAHSDMPYDAR 52.532 0.0057617 4894500 2625.6 2480.9 1926.8 2829.9 2428.5 731.13 1141.7 812.4 2479.9 2547.5 TRUE FALSE FALSE 2417.780989 2695.337941 1998.208903 2818.190624 2399.541724 579.4853965 1173.733029 1060.09702 2207.861174 2636.025435 0.917207003 1.022500734 0.758038552 1.069106006 0.910287773 0.219833006 0.4452662 0.402157356 0.83757203 1 11.36414858 -5.296619735 8.583315154 0.954907048 0.364870326 0.868541929 0.1021803 0.068360564 15.88256258 0.012658647 0.028591432 5.05E-06 5.296619735 -0.590036721 SVS(ph)RGS(ph)YQLQAQMNR ddPTM_HeLa_Curcumin_4h_R1 1 SVSRGSYQLQAQMNR 15 1 Q9H1Z4;Q9H1Z4-2 Q9H1Z4 WDR13 WD repeat-containing protein 13 2 0 S(0.23)VS(0.784)RGS(0.967)Y(0.019)QLQAQMNR 109.55 0.009092 8794900 2958.9 2676.8 2723.9 2984 2923.5 2883.5 2283.3 2173.8 2916.6 2514.4 TRUE FALSE FALSE 2724.699943 2908.170664 2824.85013 2971.652999 2888.639172 2285.429596 2347.363253 2836.581613 2596.656277 2601.775213 1.047246484 1.117763998 1.085739504 1.142163621 1.110257011 0.878411626 0.902216011 1.090248535 0.998032522 1 11.34528061 -5.265782976 24.90577306 1.049305311 0.951484454 0.32268965 0.071020043 364.2113849 2088360.428 0.010791308 0.024948309 5.42E-06 5.265782976 -0.097820858 FGVPAEGRT(ph)PPPFPGEPWK ddPTM_HeLa_Curcumin_4h_R1 2 FGVPAEGRTPPPFPGEPWK 19 1 Q9UJY1 Q9UJY1 HSPB8 Heat shock protein beta-8 1 0 FGVPAEGRT(1)PPPFPGEPWK;FGVPAEGRT(1)PPPFPGEPWK ; 100.47 0.00079503 68060000 3070.9 2298.02 2484 2514.3 2553.96 6686.5 4515.4 7065 2810.2 2667.4 TRUE FALSE FALSE 2827.835025 2496.650609 2576.059225 2503.896493 2523.505695 5299.644528 4642.089971 9219.085977 2501.928091 2760.091951 1.024543774 0.904553418 0.933323697 0.907178651 0.914283198 1.920097091 1.681860624 3.340137263 0.906465485 1 11.43050062 -2.701899748 0.739478839 0.980006526 24.50673243 0.920873066 0.210103331 3.835118288 0.237135065 0.031604413 124.7431026 0.001986553 2.701899748 23.52672591 up SVS(ph)TTNIAGHFNDESPLGLR ddPTM_HeLa_Curcumin_4h_R1 1 SVSTTNIAGHFNDESPLGLR 20 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 0 S(0.164)VS(0.627)T(0.164)T(0.044)NIAGHFNDESPLGLR 93.229 0.00044916 26250000 922.02 1161.8 1021.4 979.9 1075.8 1782.1 1079.2 1003.8 1459.7 910.13 TRUE FALSE FALSE 849.0411441 1262.220815 1059.253983 975.8454334 1062.971788 1412.472372 1109.479447 1309.853999 1299.574562 941.7569498 0.901550176 1.340282984 1.124763648 1.036196689 1.128711381 1.499826863 1.178095312 1.390862047 1.379946877 1 9.879210964 -6.028978831 0.509966383 0.953368237 1.376852623 0 0.193206676 0.735406371 0.335374571 0.038312907 0.139748905 9.35E-07 6.028978831 0.423484386 AATEALGEKSPDSATVS(ph)GYDIMK ddPTM_HeLa_Curcumin_4h_R1 1 AATEALGEKSPDSATVSGYDIMK 23 1 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;H0Y7E2;K7EL39;J3QRL2;H7C3G6 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 AATEALGEKS(0.01)PDS(0.06)AT(0.086)VS(0.539)GY(0.305)DIMK 89.011 0.00054668 21540000 1118.2 1052.7 1029.2 1289.2 945.1 1621.2 999.78 1904.3 1149.6 755.97 TRUE FALSE FALSE 1029.69329 1143.690697 1067.343057 1283.865632 933.8302998 1284.944845 1027.831136 2484.912304 1023.491756 782.2399012 1.316339512 1.46207154 1.364470229 1.641268401 1.193790164 1.642648046 1.313958971 3.176662683 1.308411594 1 9.611467318 -2.428493633 1.277510528 1.240401164 199.9999981 0.848001766 0.224048298 43.94356474 0.877461307 0.036858765 24846.39515 0.003728262 2.428493633 198.7595969 up SVS(ph)VDIR ddPTM_HeLa_Curcumin_4h_R1 2 SVSVDIR 7 0 Q6UB99 Q6UB99 ANKRD11 Ankyrin repeat domain-containing protein 11 1 0 S(0.004)VS(0.996)VDIR;S(0.004)VS(0.996)VDIR ; 101.25 0.018973 62483000 28771 19678.9 26765 30382 26258 31415 38877 29488 24212 23798 TRUE FALSE FALSE 26493.74499 21379.85643 27756.93444 30256.28733 25944.8905 24899.17488 39967.78399 38478.75545 21556.00418 24624.97873 1.075889051 0.86821827 1.127186129 1.228682781 1.053600524 1.011134879 1.62305862 1.562590404 0.875371484 1 14.58783486 -4.761220292 24.99998065 1.044824238 1.592824692 0.825847251 0.103201675 1.385100425 157942.3901 0.012580596 0.041833356 1.73E-05 4.761220292 0.548000453 VASGPSPGEGIS(ph)PQSAQAPQAPGDNHVVPVLR ddPTM_HeLa_Curcumin_4h_R1 2 VASGPSPGEGISPQSAQAPQAPGDNHVVPVLR 32 0 Q14764 Q14764 MVP Major vault protein 1 0 VAS(0.003)GPS(0.009)PGEGIS(0.531)PQS(0.458)AQAPQAPGDNHVVPVLR;VASGPS(0.001)PGEGIS(0.771)PQS(0.228)AQAPQAPGDNHVVPVLR ; 64.383 0.00015631 21201900 1270.45 1194.75 1152.96 1369.54 1320.06 2183.1 1426.75 2894.6 1608.27 1374.89 TRUE FALSE FALSE 1169.892542 1298.018866 1195.689712 1363.873206 1304.319147 1730.300451 1466.780765 3777.150215 1431.846805 1422.667325 0.822323337 0.912383973 0.840456297 0.958673319 0.916812472 1.216236868 1.031007558 2.654977835 1.006452302 1 10.47438263 -2.40052732 1.28297187 0.916773855 200 0.946389275 0.119759293 25.16869315 0.458734944 0.01726856 14354.05887 0.003976241 2.40052732 199.0832261 up VEEAS(ph)PGRPS(ph)SVDTLLSPTALIDSILR ddPTM_HeLa_Curcumin_4h_R1 1 VEEASPGRPSSVDTLLSPTALIDSILR 27 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 2 0 VEEAS(0.958)PGRPS(0.415)S(0.416)VDT(0.03)LLS(0.128)PT(0.047)ALIDS(0.005)ILR 57.735 0.0032812 9854800 2121.5 1766.3 2184.6 2092.5 2205.1 3936.6 3118.1 7119.8 2072.9 1764.4 TRUE FALSE FALSE 1953.581036 1918.971102 2265.563198 2083.841789 2178.805623 3120.104785 3205.585494 9290.594244 1845.508056 1825.712769 1.070037451 1.051080506 1.240919841 1.14138534 1.193400003 1.708979002 1.75579946 5.08874912 1.010842498 1 10.83424409 -2.394524571 1.049287574 1.067267389 200 0.97630702 0.18209146 7.607454727 0.21088509 0.026105205 3438.83552 0.004031581 2.394524571 198.9327326 up SVSCDNVS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SVSCDNVSK 9 0 A0A087WXN4;Q96CB8 A0A087WXN4 INTS12 Integrator complex subunit 12 1 0 S(0.007)VS(0.057)CDNVS(0.936)K 105.17 0.010711 232500000 3016.8 2636.9 3189.2 3220 2633.2 3555 3004.3 3657.7 3111.7 2863 TRUE FALSE FALSE 2778.017097 2864.821886 3307.394558 3206.676493 2601.80081 2817.652927 3088.592572 4772.915892 2770.354295 2962.489037 0.93773076 0.967032063 1.116424235 1.082426451 0.878248249 0.951109993 1.042566752 1.611116812 0.935144151 1 11.5325941 -4.261532594 3.855757761 0.980757595 1.672901202 0.886821303 0.066843722 0.059323141 1.731141708 0.00954047 0.115564862 5.48E-05 4.261532594 0.692143607 SVSDNDIR ddPTM_HeLa_Curcumin_4h_R1 1 SVSDNDIR 8 0 P55072 P55072 VCP Transitional endoplasmic reticulum ATPase 0 0 110.12 0.0064354 5462900 6602.1 6119.2 6119.8 6557.5 6264.8 7394.5 5282.4 6032.4 7175.4 6374.8 FALSE FALSE TRUE 6079.536818 6648.116381 6346.605172 6530.366803 6190.096352 5860.797347 5430.609927 7871.65099 6388.276572 6596.323826 0.921655301 1.00785173 0.962142754 0.990000942 0.938416081 0.888494486 0.823278249 1.193339078 0.968460121 1 12.68744651 -5.730552494 24.15748441 0.967495353 0.945882597 0 0.092161958 747.1801246 584384.3322 0.012607534 0.025212549 1.86E-06 5.730552494 -0.021612757 SVSDYDGK ddPTM_HeLa_Curcumin_4h_R1 2 SVSDYDGK 8 0 P07237;H7BZ94;I3L398;I3L312;I3L4M2 P07237 P4HB Protein disulfide-isomerase 0 0 ; ; 137.9 0.00089719 7324800 6123.1 6004.6 6461.6 4983.4 5927.5 6604.9 4360.6 3163.2 4310.4 4936.8 FALSE FALSE TRUE 5638.450174 6523.610868 6701.07258 4962.780011 5856.818434 5234.969287 4482.9467 4127.645118 3837.559904 5108.353433 1.103770569 1.277047674 1.311787187 0.971502868 1.146517858 1.02478604 0.877571758 0.808018704 0.751232262 1 12.31864263 -4.754699093 2.48225076 1.087762454 0.816273772 0.283967244 0.14993248 0.223733368 2.657435458 0.016941611 0.083080425 1.76E-05 4.754699093 -0.271488682 SVSEINS(ph)DDELSGK ddPTM_HeLa_Curcumin_4h_R1 3 SVSEINSDDELSGK 14 0 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 0 S(0.027)VS(0.061)EINS(0.912)DDELSGK;S(0.021)VS(0.424)EINS(0.555)DDELS(0.001)GK;SVS(0.01)EINS(0.989)DDELS(0.001)GK ;; 213.94 9.58E-14 339632600 14447.2 12644.7 13645.6 13823.1 14033.3 15846.6 11831.59 5890.68 13895.1 11848.96 TRUE FALSE FALSE 13303.68888 13737.65152 14151.31794 13765.90367 13865.96206 12559.83653 12163.55257 7686.721215 12370.84229 12260.71048 1.085066718 1.120461294 1.154200482 1.122765577 1.130926473 1.024397122 0.992075671 0.626939298 1.008982499 1 13.58175496 -4.166218081 2.071520298 1.066786174 0.425586356 0.869067803 0.052509437 0.308572898 1.158493169 0.009039402 0.40255725 6.82E-05 4.166218081 -0.641199818 SVSEINS(ph)DDELSGKGYALVPIIVNSSTPK ddPTM_HeLa_Curcumin_4h_R1 1 SVSEINSDDELSGKGYALVPIIVNSSTPK 29 1 F8WF45;A0A2R8Y7M0;P82094;P82094-2 F8WF45 TMF1 TATA element modulatory factor 1 0 S(0.005)VS(0.012)EINS(0.801)DDELS(0.095)GKGY(0.087)ALVPIIVNSSTPK 59.555 0.0010527 13960000 2842.5 1816.2 1374.3 1919.9 1110.8 2473.8 1358.3 1022.1 3133.2 2654 TRUE FALSE FALSE 2617.513126 1973.184235 1425.232767 1911.955963 1097.554435 1960.705995 1396.410242 1333.733585 2789.495799 2746.226302 0.953130892 0.718507515 0.518978631 0.696212093 0.399659138 0.713963737 0.508483311 0.48566048 1.015755984 1 11.4232348 -7.115272232 2.237751128 0.981854352 0.556913259 0.823795468 0.090021399 0.079339153 0.768612567 0.014348649 0.017953812 7.67E-08 7.115272232 -0.424941093 AEPVPGGQTSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 AEPVPGGQTSSPR 13 0 O15018-2;O15018 O15018-2 PDZD2 PDZ domain-containing protein 2;Processed PDZ domain-containing protein 2 1 0 AEPVPGGQT(0.01)S(0.033)S(0.957)PR 147.7 0.00065456 20315000 3281.7 2651.6 3204.5 3104.3 3007.5 3125.5 2489.6 838.14 3614 2676.9 TRUE FALSE FALSE 3021.949982 2880.792489 3323.261589 3091.455229 2971.637527 2477.236068 2559.451476 1093.685028 3217.553242 2769.922076 1.090987363 1.040026546 1.199767177 1.116080216 1.072823511 0.894334209 0.924015696 0.394843247 1.161604245 1 11.43562968 -4.120518474 1.428311012 1.059071766 2.04E-13 0.874293691 0.077412485 0.42470609 0.599324608 0.010965137 0.702388683 7.58E-05 4.120518474 -1.059071766 down SVSGS(ph)PEPAAK ddPTM_HeLa_Curcumin_4h_R1 2 SVSGSPEPAAK 11 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 S(0.318)VS(0.184)GS(0.499)PEPAAK;S(0.038)VS(0.072)GS(0.89)PEPAAK ; 162.49 0.00030547 386920000 16053.4 12756.1 13227.5 13883 13485.7 15183 12560.4 17345.9 15883.5 11165.8 TRUE FALSE FALSE 14782.75645 13858.68044 13717.72279 13825.55582 13324.89184 12033.87465 12912.81102 22634.58506 14141.11979 11553.81072 1.279470195 1.199490002 1.187289901 1.196623016 1.153289781 1.041550268 1.117623556 1.959057977 1.22393556 1 13.49608114 -4.260417255 24.93615816 1.141605094 1.959058245 0.899103143 0.080637743 24.15821963 589286.3771 0.015113843 0.123833575 5.49E-05 4.260417255 0.817453151 SVSLT(ph)IY ddPTM_HeLa_Curcumin_4h_R1 1 SVSLTIY 7 0 P30291;P30291-2 P30291 WEE1 Wee1-like protein kinase 1 0 SVS(0.001)LT(0.984)IY(0.014) 117.93 0.0039309 6385600 8481.6 6398.5 7605.9 7645.6 7248.2 10299 9083.1 8476.6 8611.9 6914.5 TRUE FALSE FALSE 7810.27241 6951.557829 7887.781345 7613.964533 7161.769949 8162.871306 9337.94734 11061.07632 7667.196116 7154.77836 1.091616262 0.97159653 1.102449433 1.064178951 1.000977192 1.140897858 1.305134397 1.545970506 1.071618956 1 12.80469136 -4.456661823 1.439939213 1.04164959 1.647056627 0.935181931 0.042021948 0.152298459 0.368168814 0.006703959 0.118508629 3.49E-05 4.456661823 0.605407037 SVSMLSLNT(ph)PNSNR ddPTM_HeLa_Curcumin_4h_R1 2 SVSMLSLNTPNSNR 14 0 Q9H8V3-2;Q9H8V3-4;Q9H8V3;Q9H8V3-3;H7C3G1 Q9H8V3-2 ECT2 Protein ECT2 1 0 SVSMLS(0.019)LNT(0.981)PNSNR;SVSMLS(0.1)LNT(0.899)PNSNR ; 129.29 0.0032329 30072000 2751.6 1831.97 1929.8 2371.2 1993.93 2651.9 2446 1047.26 2929.7 2317.2 TRUE FALSE FALSE 2533.807957 1990.317324 2001.320086 2361.388603 1970.153687 2101.866047 2514.628177 1366.564753 2608.31924 2397.722528 1.056756121 0.830086593 0.834675432 0.984846485 0.821677098 0.876609375 1.048756955 0.569942826 1.087831978 1 11.227449 -7.262304834 24.97986814 1.026801503 0.864090369 0.351093375 0.120218133 67.03914469 1934959.321 0.018249834 0.021535076 5.47E-08 7.262304834 -0.162711134 EAPS(ph)PTLRR ddPTM_HeLa_Curcumin_4h_R1 2 EAPSPTLRR 9 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 EAPS(0.899)PT(0.101)LRR;EAPS(0.972)PT(0.028)LRR ; 84.188 0.007583 118280000 3066.2 2137.8 2325.8 2680.6 2578.5 3076.9 2085.7 810.61 3259.3 2593 TRUE FALSE FALSE 2823.507035 2322.581906 2411.996194 2669.508387 2547.753072 2438.716256 2144.219129 1057.761257 2901.762944 2683.106557 1.052327582 0.865631631 0.898956543 0.994931931 0.949553444 0.908915171 0.799155413 0.394230059 1.08149374 1 11.38968864 -4.120361946 1.221104217 0.997630177 7.49E-20 0.882996147 0.063492643 0.475364445 0.472233879 0.009985608 0.646473958 7.58E-05 4.120361946 -0.997630177 down SVSPS(ph)PVPLLFQPDQNAPPIR ddPTM_HeLa_Curcumin_4h_R1 1 SVSPSPVPLLFQPDQNAPPIR 21 0 Q02241-2;Q02241-3 Q02241-2 KIF23 Kinesin-like protein KIF23 1 0 S(0.012)VS(0.346)PS(0.641)PVPLLFQPDQNAPPIR 115.91 1.24E-05 236990000 2816.9 2652.5 2717.9 2995.2 2495.9 3875.1 2830.9 2287.3 3561.5 2588.5 TRUE FALSE FALSE 2593.939393 2881.770281 2818.627765 2982.806656 2466.138023 3071.360579 2910.327435 2984.687241 3170.81236 2678.450182 0.968447877 1.075909606 1.052335333 1.11363156 0.920733206 1.146693188 1.086571426 1.114333677 1.183823534 1 11.38718275 -7.256484615 24.43195319 0.985100386 1.071176492 0 0.085208873 251.8887315 1242063.926 0.009182378 0.011052976 5.54E-08 7.256484615 0.086076106 SVSPT(ph)FLNPSDENLK ddPTM_HeLa_Curcumin_4h_R1 1 SVSPTFLNPSDENLK 15 0 Q9UKA4 Q9UKA4 AKAP11 A-kinase anchor protein 11 1 0 S(0.006)VS(0.136)PT(0.858)FLNPSDENLK 101.72 0.0097725 4731200 1574.3 1511.8 1732.2 1631.8 1712.6 1860.4 1164 998.88 1930.1 1555.9 TRUE FALSE FALSE 1449.692494 1642.473256 1796.396856 1625.048044 1692.178364 1474.532069 1196.658707 1303.433914 1718.372859 1609.967409 0.900448348 1.020190375 1.115797031 1.009367044 1.051063738 0.915876968 0.743281324 0.80960267 1.06733394 1 10.65281577 -4.905446475 4.431947665 0.979842714 0.77830571 0.660323215 0.065606982 0.115170322 4.016251961 0.010218482 0.032904579 1.24E-05 4.905446475 -0.201537004 SVSPT(ph)TEMVSNESVDYR ddPTM_HeLa_Curcumin_4h_R1 1 SVSPTTEMVSNESVDYR 17 0 P08581;P08581-2 P08581 MET Hepatocyte growth factor receptor 1 0 S(0.005)VS(0.151)PT(0.841)T(0.003)EMVSNESVDYR 143.83 0.00087528 20206000 1954.8 1603.1 1663.9 2291.7 1411.7 1558.7 1093.3 1196.2 2977 2141.6 TRUE FALSE FALSE 1800.075517 1741.664821 1725.565598 2282.217553 1394.8664 1235.40805 1123.975056 1560.915873 2650.430548 2216.020441 0.812300954 0.785942579 0.778677654 1.029872067 0.62944654 0.557489465 0.507204282 0.704377922 1.196031634 1 11.11375547 -3.615453615 0.139549369 1.082158533 2.69E-12 0.58399601 0.134252452 19.28677105 0.36815439 0.429688276 3.913382264 0.000242408 3.615453615 -1.082158533 SVSPTTEMVS(ph)NES(ph)VDYR ddPTM_HeLa_Curcumin_4h_R1 2 SVSPTTEMVSNESVDYR 17 0 P08581;P08581-2 P08581 MET Hepatocyte growth factor receptor 2 0 SVSPTTEMVS(1)NES(1)VDYR;SVS(0.007)PT(0.072)T(0.072)EMVS(0.848)NES(1)VDYR ; 158.17 0.00038071 14168200 2563.3 2807.8 3094.9 5339.8 3826.2 7452 1595.22 360.28 4876 3049.5 TRUE FALSE FALSE 2360.4121 3050.493721 3209.599717 5317.705322 3780.575064 5906.371199 1639.97758 470.1277135 4341.114999 3155.469898 0.748038225 0.966731998 1.017154281 1.685234052 1.198102085 1.871788161 0.519725313 0.148988179 1.375742802 1 11.62363915 -6.758289224 3.54999012 0.881714112 1.121846191 0 0.497979746 0.623733814 16.74675124 0.079118437 0.109987926 1.74E-07 6.758289224 0.240132079 SVSPTTEMVS(ph)NESVDYR ddPTM_HeLa_Curcumin_4h_R1 1 SVSPTTEMVSNESVDYR 17 0 P08581;P08581-2 P08581 MET Hepatocyte growth factor receptor 1 0 SVSPTTEMVS(0.997)NES(0.002)VDYR 93.738 0.0039661 0 808.71 664.61 796.41 1056.2 819 1424.1 458.19 486.56 1299.6 1039.9 TRUE FALSE FALSE 744.6997502 722.055927 825.9256552 1051.829724 809.2339599 1128.725607 471.0455782 634.9099042 1157.037131 1076.036448 0.692076697 0.671032964 0.767562899 0.977503807 0.752050697 1.048965962 0.437759873 0.59004498 1.075276896 1 10.07151123 -9.32260734 0.971649525 1.004872552 0.745685656 0.322300891 0.167942749 0.676520389 1.110257445 0.125246535 0.030818558 4.76E-10 9.32260734 -0.259186896 SVSPVQDLDDDT(ph)PPS(ph)PAHSDMPYDAR ddPTM_HeLa_Curcumin_4h_R1 2 SVSPVQDLDDDTPPSPAHSDMPYDAR 26 0 G3V3A7;O00409-2;O00409 G3V3A7 FOXN3 Forkhead box protein N3 2 0 S(0.083)VS(0.326)PVQDLDDDT(0.59)PPS(0.908)PAHS(0.071)DMPY(0.021)DAR;S(0.061)VS(0.282)PVQDLDDDT(0.657)PPS(0.999)PAHSDMPYDAR ; 95.19 8.37E-06 9704100 710.24 967.73 885.64 945.92 865.44 859.96 506.03 564.15 1019.46 789.52 TRUE FALSE FALSE 654.0237546 1051.376269 918.4625975 942.0060337 855.1201932 681.5946023 520.2278399 736.156738 907.6277886 816.9557612 0.80056202 1.286943944 1.124250102 1.153068597 1.046715421 0.834310295 0.636788263 0.901097431 1.110987683 1 9.674114147 -5.06827102 5.411899754 0.976515032 0.760829374 0.303725014 0.154658182 0.244303532 13.6219478 0.024991171 0.066567728 8.55E-06 5.06827102 -0.215685658 DKRPLS(ph)GPDVGTPQPAGLASGAK ddPTM_HeLa_Curcumin_4h_R1 1 DKRPLSGPDVGTPQPAGLASGAK 23 2 O96013 O96013 PAK4 Serine/threonine-protein kinase PAK 4 1 0 DKRPLS(1)GPDVGTPQPAGLASGAK 109.69 1.10E-05 107980000 5923 4144.6 4147.3 5524 5385.5 5572.9 4013.7 1617.9 5941.6 5181.5 TRUE FALSE FALSE 5454.1883 4502.840756 4301.002586 5501.143152 5321.28143 4417.01772 4126.31362 2111.190262 5289.821345 5361.556739 1.01727699 0.839838311 0.80219287 1.02603468 0.992488131 0.8238312 0.769611107 0.393764417 0.986620417 1 12.38843624 -4.119487456 1.056169088 0.981110391 1.18E-18 0.809384576 0.080008349 0.723526477 0.521624096 0.013188032 0.851628857 7.59E-05 4.119487456 -0.981110391 down SVSQPVAQK(ac)QECK ddPTM_HeLa_Curcumin_4h_R1 1 SVSQPVAQKQECK 13 1 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2;H7BXU7 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 0 1 SVSQPVAQK(1)QECK 266.78 2.00E-77 1926200 780.11 899.83 956.21 609.69 701.78 912.93 470.8 136.91 565.2 732.7 FALSE TRUE FALSE 718.3634703 977.6072956 991.6479838 607.1672643 693.4117318 723.5780272 484.0093809 178.6532287 503.1989741 758.1612705 0.947507474 1.289445048 1.307964443 0.800841837 0.914596615 0.954385373 0.638398979 0.235640141 0.66370968 1 9.56636095 -4.351828374 1.350322146 1.011055642 1.10E-16 0.620978165 0.184989385 0.464623113 0.827316896 0.023147797 0.609993532 4.45E-05 4.351828374 -1.011055642 SVSS(ph)FPVPQDNVDTHPGSGK ddPTM_HeLa_Curcumin_4h_R1 1 SVSSFPVPQDNVDTHPGSGK 20 0 C9JAY7;E7EVC7;Q676U5-4;Q676U5-5;Q676U5-3;Q676U5-2;Q676U5 C9JAY7 ATG16L1 Autophagy-related protein 16-1 1 0 S(0.28)VS(0.316)S(0.404)FPVPQDNVDTHPGSGK 65.213 0.0044801 3323100 1243.3 966.22 1154.8 833.5 1442.7 2414.3 1700.1 1497.4 1556.7 1091.6 TRUE FALSE FALSE 1144.891493 1049.735751 1197.597904 830.0511978 1425.496745 1913.546965 1747.80023 1953.950367 1385.933905 1129.533019 1.013597189 0.929353754 1.060259314 0.73486227 1.262023085 1.694104496 1.547365328 1.729874501 1.226997247 1 10.14151073 -5.451061239 3.787170063 0.987271217 1.641444839 0.84802072 0.125120443 0.046260849 1.273863898 0.0132445 0.030533384 3.54E-06 5.451061239 0.654173622 TCPSLSPT(ph)SPLNNK ddPTM_HeLa_Curcumin_4h_R1 1 TCPSLSPTSPLNNK 14 0 O75925;O75925-2 O75925 PIAS1 E3 SUMO-protein ligase PIAS1 1 0 TCPSLS(0.331)PT(0.414)S(0.255)PLNNK 158.31 0.00097129 15872000 2264.1 1621 1843.2 2210.1 1952.2 2120.9 1407.1 689.95 2214.7 2019.8 TRUE FALSE FALSE 2084.894096 1761.112017 1911.510613 2200.955192 1928.92129 1681.001433 1446.579439 900.3125789 1971.752951 2089.9879 0.997562759 0.842642207 0.914603675 1.053094706 0.92293419 0.804311562 0.69214728 0.430774063 0.943427927 1 11.02927887 -4.118866776 0.811760148 0.986060193 3.23E-16 0.884456732 0.059414778 0.645409921 0.263454655 0.009770653 0.602403896 7.61E-05 4.118866776 -0.986060193 down SVSS(ph)SSYR ddPTM_HeLa_Curcumin_4h_R1 1 SVSSSSYR 8 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 0 SVS(0.073)S(0.911)S(0.008)S(0.008)YR 171.33 0.00054965 12110000 10014 8236.7 7690.5 9882.2 8408.9 12281 10794 13427 10295 8549 TRUE FALSE FALSE 9221.381333 8948.643646 7975.516695 9841.310075 8308.62936 9733.782165 11096.85059 17520.83049 9165.664257 8846.077114 1.042426062 1.011594578 0.901587969 1.112505571 0.939244509 1.100350137 1.254437469 1.980632801 1.036127556 1 13.1108221 -4.115752259 1.631358658 1.01344265 2.612544926 0.961956642 0.057714957 0.173631948 0.328566665 0.007553194 0.487221539 7.66E-05 4.115752259 1.599102276 SVSS(ph)YGNIR ddPTM_HeLa_Curcumin_4h_R1 1 SVSSYGNIR 9 0 Q8N122-3;Q8N122 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 0 SVS(0.019)S(0.981)YGNIR 181.87 0.0013438 99677000 4491.1 4233 4237.3 4054.8 3365.7 5489.6 3646.6 2899.2 5827.4 5490 TRUE FALSE FALSE 4135.624696 4598.881658 4394.338066 4038.022312 3325.566226 4350.995079 3748.913782 3783.152734 5188.148799 5680.777091 0.72800334 0.809551508 0.773545238 0.710822172 0.585406921 0.765915474 0.659929746 0.665956906 0.913281531 1 12.47187258 -13.52287875 0.174815748 2.237623157 0.635654201 0.738996595 0.05969637 16.51126504 0.186296945 6.929125979 0.079729334 3.00E-14 13.52287875 -1.601968956 SVSSNVAS(ph)VSPIPAGSKK ddPTM_HeLa_Curcumin_4h_R1 1 SVSSNVASVSPIPAGSKK 18 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 0 SVSSNVAS(0.624)VS(0.376)PIPAGSKK 135.66 0.00013092 139160000 4609.3 3653.8 3436.1 4381.8 3700.7 5795.1 4648.9 3075.1 4551.9 3616.4 TRUE FALSE FALSE 4244.469041 3969.618191 3563.444889 4363.669273 3656.57157 4593.130936 4779.335622 4012.683834 4052.567958 3742.069631 1.134257098 1.060808211 0.952265789 1.166111191 0.977152199 1.227430644 1.277190457 1.07231672 1.082975027 1 11.86962069 -1 0.075151863 0.918396539 1.580646131 0.146580007 0.093502584 254.953153 1.419227422 2.074890112 17.76390511 0.1 1 0.662249593 SVSSNVASVS(ph)PIPAGSK ddPTM_HeLa_Curcumin_4h_R1 3 SVSSNVASVSPIPAGSK 17 0 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 0 SVSSNVAS(0.068)VS(0.932)PIPAGSK;SVSSNVAS(0.001)VS(0.999)PIPAGSK;SVSSNVAS(0.036)VS(0.492)PIPAGS(0.471)K ;; 229.93 3.69E-22 105366000 14879.7 11985.9 12533 13005.6 12684.8 20122.9 18076 6981.4 13661.1 10460.2 TRUE FALSE FALSE 13701.95604 13021.90779 12997.48401 12951.78627 12533.54204 15949.18371 18583.16391 9109.996722 12162.51151 10823.69117 1.265922672 1.203093065 1.200836554 1.196614544 1.157972991 1.473543864 1.716897093 0.841671901 1.123693509 1 13.40190496 -13.07927758 0.180145128 3.04E-08 1.34420183 0.098401347 0.216340894 56.08827255 0.743110873 19.86738319 0.289019866 8.33E-14 13.07927758 1.3442018 SVSSNVASVS(ph)PIPAGSKK ddPTM_HeLa_Curcumin_4h_R1 1 SVSSNVASVSPIPAGSKK 18 1 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 0 SVSSNVAS(0.01)VS(0.99)PIPAGSKK 164.69 8.63E-06 112280000 5647.6 4486.2 4443.7 4680.5 5204.1 9140.7 6871.8 2813.9 6677.6 5018.9 TRUE FALSE FALSE 5200.586501 4873.967138 4608.387431 4661.133331 5142.044506 7244.815783 7064.604213 3671.845156 5945.083987 5193.306401 1.001401824 0.938509451 0.887370603 0.897527119 0.990129237 1.395029529 1.36032879 0.707034185 1.144758951 1 12.34243763 -5.474989094 24.9703547 0.978179772 1.17772222 0.151841079 0.186334042 450.0215083 234647.179 0.023944889 0.053541079 3.35E-06 5.474989094 0.199542447 SVSSNVASVSPIPAGS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SVSSNVASVSPIPAGSK 17 0 Q9Y6G9;E9PHI6 Q9Y6G9 DYNC1LI1 Cytoplasmic dynein 1 light intermediate chain 1 1 0 SVSSNVASVS(0.02)PIPAGS(0.98)K 142.76 0.00031548 68300000 6869.8 6232.8 6172 6698.7 6705.9 10759 8784.2 3564.9 6890.6 5192.8 TRUE FALSE FALSE 6326.048081 6771.535459 6400.739749 6670.982554 6625.936522 8527.462121 9030.661011 4651.821599 6134.718419 5373.249413 1.177322621 1.260230996 1.191223272 1.241517384 1.233133996 1.587021459 1.680670357 0.865737144 1.141714807 1 12.39157909 -7.452545939 0.382769372 0.995703309 1.386775316 0.151277346 0.211823504 1.042060526 0.433282407 0.138620692 0.13449792 3.53E-08 7.452545939 0.391072007 SSGPYGGGGQYFAK(ac)PR ddPTM_HeLa_Curcumin_4h_R1 2 SSGPYGGGGQYFAKPR 16 1 F8W6I7;P09651-2;P09651;P09651-3;H0YH80 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 0 1 ; SSGPYGGGGQYFAK(1)PR;SSGPYGGGGQYFAK(1)PR 282.21 2.32E-93 109208000 1227.9 1048.86 1357.21 1072.7 1384.49 2212.26 1540.97 1915.1 1536.74 1138.14 FALSE TRUE FALSE 1130.710419 1139.518785 1407.509397 1068.261452 1367.980861 1753.412339 1584.205471 2499.005174 1368.163467 1177.69028 0.960108475 0.967587832 1.195143936 0.907081827 1.161579478 1.488856933 1.345180051 2.121954487 1.161734532 1 10.20174446 -1 0.536133882 0.980919648 45.78116284 0.853264382 0.131879895 22.87928277 0.199055066 0.020327018 1179.445505 0.1 1 44.80024319 up SSAWAEGGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 SSAWAEGGSPR 11 0 Q8N9B5-2;Q8N9B5 Q8N9B5-2 JMY Junction-mediating and -regulatory protein 1 0 SSAWAEGGS(1)PR;SSAWAEGGS(1)PR;SSAWAEGGS(1)PR ;; 148.13 0.0007746 81815000 8250.3 7094.2 6804.4 7817.7 7655.1 8289.5 5716.73 2397.78 8100.3 7349.9 TRUE FALSE FALSE 7597.280049 7707.391037 7056.57705 7785.352429 7563.817932 6570.164258 5877.126058 3128.852084 7211.717356 7605.308478 0.998944365 1.01342254 0.927848893 1.023673458 0.994544528 0.863891883 0.772766295 0.411403705 0.948247843 1 12.89279105 -4.117727079 1.099086366 0.997500765 9.55E-20 0.961692081 0.034792984 0.226951862 0.178085052 0.004320667 0.281640063 7.63E-05 4.117727079 -0.997500765 down SVSSS(ph)SYR ddPTM_HeLa_Curcumin_4h_R1 1 SVSSSSYR 8 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 0 SVS(0.046)S(0.332)S(0.548)S(0.074)YR 95.358 0.01777 37745000 5714 5190.9 5665.7 5209.5 6636.2 7682.6 7091.7 3214.4 5338.8 5165.9 TRUE FALSE FALSE 5261.730871 5639.578266 5875.675826 5187.944469 6557.067649 6089.142159 7290.674016 4194.455763 4753.146997 5345.41464 0.984344756 1.055031021 1.099199262 0.970541075 1.226671473 1.139133738 1.363911783 0.784682956 0.889200804 1 12.38408615 -6.482159935 1.021762803 0.993170695 1.133511794 0.130947406 0.147251547 0.672662062 1.400424918 0.024142311 0.044231744 3.29E-07 6.482159935 0.140341099 SVSSS(ph)SYRR ddPTM_HeLa_Curcumin_4h_R1 3 SVSSSSYRR 9 1 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 0 SVSS(0.003)S(0.498)S(0.498)YRR;SVS(0.001)S(0.003)S(0.587)S(0.41)YRR;SVSS(0.002)S(0.499)S(0.499)YRR ;; 80.102 0.015153 268606000 5372.2 4541.1 4587.2 4321.8 4368.4 6698.5 5481 3038.84 4709.1 4977.1 TRUE FALSE FALSE 4946.984701 4933.612449 4757.205667 4303.917537 4316.309683 5309.155592 5634.782109 3965.368327 4192.523512 5150.053855 0.960569509 0.957972982 0.923719596 0.835703404 0.838109621 1.030893218 1.094121007 0.769966381 0.814073722 1 12.3303718 -7.615715439 1.030190009 0.989230752 0.924425454 0 0.10531233 0.894575624 1.957795118 0.021521728 0.021344227 2.42E-08 7.615715439 -0.064805298 SVSSSS(ph)YR ddPTM_HeLa_Curcumin_4h_R1 1 SVSSSSYR 8 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 1 0 SVS(0.005)S(0.035)S(0.063)S(0.897)YR 119.21 0.0085211 33487000 5080.3 4722.4 4961.9 4343.5 5673.8 6294.5 5659.4 3052.4 4548.9 4484.8 TRUE FALSE FALSE 4678.188894 5130.583213 5145.792379 4325.527748 5606.143641 4988.949746 5818.187533 3983.062708 4049.897051 4640.646466 1.008089913 1.105575107 1.108852488 0.932095944 1.208052301 1.075054905 1.253745049 0.858299105 0.872701052 1 12.18011008 -7.274924951 20.64815597 1.003820199 1.084724035 0.142624836 0.116908959 121.584956 186161.3853 0.016796762 0.019301924 5.31E-08 7.274924951 0.080903836 SVSSSSYR ddPTM_HeLa_Curcumin_4h_R1 2 SVSSSSYR 8 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 0 0 ; ; 101.6 0.011953 2291500 1735.36 675.49 987.57 833.8 1268.84 1587.57 1554.55 1059.35 817.49 1187.17 FALSE FALSE TRUE 1598.004425 733.8763457 1024.170213 830.3499565 1253.709912 1258.290086 1598.166489 1382.340938 727.8133923 1228.424069 1.300857306 0.597412868 0.833726918 0.675947319 1.020583969 1.024312465 1.300989234 1.125296201 0.592477313 1 10.26259297 SVSSVLSSLT(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 2 SVSSVLSSLTPAK 13 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 0 SVSSVLS(0.002)S(0.007)LT(0.991)PAK;SVSSVLS(0.018)S(0.043)LT(0.94)PAK ; 139.74 0.0029125 175121000 5469.4 4753 4489.4 4727.7 4788 8552 8079 1818.55 5393.7 5037 TRUE FALSE FALSE 5036.491219 5163.828141 4655.781113 4708.13803 4730.906227 6778.218799 8305.674996 2373.017523 4802.024604 5212.035375 0.966319462 0.990750785 0.893275041 0.903320429 0.907688818 1.300493629 1.593556912 0.455295744 0.921333847 1 12.34763116 -5.276078077 24.55437027 0.966657725 1.164159587 0.068904383 0.268715002 996.0553718 1670743.425 0.034520912 0.077528618 5.30E-06 5.276078077 0.197501863 DGSLASNPYS(ph)GDLTK ddPTM_HeLa_Curcumin_4h_R1 1 DGSLASNPYSGDLTK 15 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5;H0Y5H6;H7C2T8 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 0 DGSLASNPYS(0.999)GDLT(0.001)K 115.56 0.0024563 0 916.95 846.07 1034.7 988.57 1003.3 1460.6 977.64 1896.4 1145.6 816.23 TRUE FALSE FALSE 844.3724399 919.2005208 1073.046892 984.4795593 991.3363028 1157.655096 1005.069947 2474.60363 1019.930546 844.5939317 0.999737753 1.088334271 1.270488517 1.165624713 1.173743104 1.370664709 1.190003751 2.929932997 1.207598714 1 9.722114071 -2.33952807 1.217620729 1.054648222 199.9999857 0.922545212 0.150554795 28.52716518 0.502657382 0.02226454 15401.4263 0.004575852 2.33952807 198.9453375 up SVST(ph)TNIAGHFNDESPLGLR ddPTM_HeLa_Curcumin_4h_R1 1 SVSTTNIAGHFNDESPLGLR 20 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 0 S(0.036)VS(0.151)T(0.646)T(0.168)NIAGHFNDESPLGLR 111.56 0.00020683 28323000 795.41 1011.3 785.32 638.48 760.88 1448.9 1075.3 879.6 805.28 784.49 TRUE FALSE FALSE 732.4524592 1098.712266 814.42465 635.8381389 751.8070029 1148.381808 1105.470024 1147.785991 716.9427987 811.7509691 0.902311777 1.353509029 1.003293721 0.783292122 0.926154734 1.414697181 1.361833944 1.413963191 0.88320535 1 9.664893392 -5.259339972 24.79644038 0.972701067 1.393331718 0.647522737 0.141271568 78.38223238 925774.8399 0.020349956 0.049187206 5.50E-06 5.259339972 0.420630651 SVSTPS(ph)EAGSQDSGDGAVGSR ddPTM_HeLa_Curcumin_4h_R1 2 SVSTPSEAGSQDSGDGAVGSR 21 0 E7EQL5;Q13409-2;E7EV09;Q13409-3;Q13409-6;E7EQU2;E9PGG1;E7ETL8;E7ESD3;E7EMU4;Q13409;Q13409-7;Q13409-5;E7ET01;E7ERR6;E7EUM4;E7ERH4 E7EQL5 DYNC1I2 Cytoplasmic dynein 1 intermediate chain 2 1 0 S(0.001)VS(0.006)T(0.029)PS(0.702)EAGS(0.008)QDS(0.254)GDGAVGSR;SVS(0.094)T(0.094)PS(0.81)EAGS(0.001)QDSGDGAVGSR ; 303.73 7.97E-103 38752000 3000 2644.7 2744.2 2689.2 2764.9 3424.5 2789.9 3855.6 3121 2603.8 TRUE FALSE FALSE 2762.546834 2873.296083 2845.902466 2678.072803 2731.930373 2714.220098 2868.177085 5031.154691 2778.634108 2694.281856 1.025336985 1.066442279 1.056274962 0.993983906 1.013973489 1.007400206 1.06454233 1.867345348 1.03130788 1 11.39568507 -4.260804429 4.752956427 1.018295273 1.916302558 0.99209286 0.022478463 0.011594722 0.731364351 0.003442905 0.034392232 5.49E-05 4.260804429 0.898007285 SVSTTNIAGHFNDES(ph)PLGLR ddPTM_HeLa_Curcumin_4h_R1 1 SVSTTNIAGHFNDESPLGLR 20 0 V9GYM8;A0A5F9ZI21;Q92974-3;Q92974-2;Q92974;V9GYF5;V9GYG5;V9GZ14 V9GYM8 ARHGEF2 Rho guanine nucleotide exchange factor 2 1 0 SVS(0.001)T(0.006)T(0.008)NIAGHFNDES(0.985)PLGLR 95.926 0.00037532 12646000 2061.8 1545.2 1499.7 1536.8 1947.8 2840.2 1978.6 607.01 1782.5 1146.9 TRUE FALSE FALSE 1898.606354 1678.760203 1555.280201 1530.441129 1924.573757 2251.110504 2034.114191 792.0845547 1586.96421 1186.75469 1.599830505 1.414580635 1.310532172 1.289601922 1.621711525 1.896862531 1.714014032 0.667437476 1.337230199 1 10.21280604 -9.392366054 1.002808905 0.986854902 1.470769654 0.055425409 0.330066099 0.673665404 1.158354347 0.242721527 0.055690918 4.05E-10 9.392366054 0.483914752 SVTEQGAELSNEER ddPTM_HeLa_Curcumin_4h_R1 5 SVTEQGAELSNEER 14 0 P63104;E7EX29;E7ESK7;E5RIR4;E9PD24;E7EVZ2;E5RGE1 P63104 YWHAZ 14-3-3 protein zeta/delta 0 0 ;;;; ;;;; 378.52 2.68E-290 616877000 5539.76 4431.59 4594.83 4766.01 4750.7 5585.29 4419.58 4394.93 5373.74 4635.86 FALSE FALSE TRUE 5101.28215 4814.636893 4765.118442 4746.289513 4694.051005 4426.837895 4543.58152 5734.923925 4784.254166 4796.95579 1.06344156 1.003685901 0.99336301 0.989437827 0.978547898 0.922843172 0.947180195 1.195534038 0.997352149 1 12.22790343 -7.025646634 22.03293044 1.030148269 0.996490668 0 0.071377976 443.3018679 380838.561 0.011508225 0.014138102 9.43E-08 7.025646634 -0.033657601 SVTLLIK ddPTM_HeLa_Curcumin_4h_R1 2 SVTLLIK 7 0 P40227;P40227-2 P40227 CCT6A T-complex protein 1 subunit zeta 0 0 ; ; 117.17 0.009824 18942600 8353.8 5263.4 8056 6567.7 7439.9 9537.1 7569.8 7096 7849.4 6841 FALSE FALSE TRUE 7692.587915 5718.344843 8354.562447 6540.524598 7351.184052 7558.997955 7782.188215 9259.537734 6988.340458 7078.724241 1.086719535 0.807821388 1.180235613 0.923969401 1.03848996 1.067847496 1.099377225 1.308080018 0.987231628 1 12.78927366 -3.91207922 1.28105115 1.026103115 1.675634362 0.47508611 0.094124373 1.974750539 1.521135545 0.012731159 2.084498215 0.000122439 3.91207922 0.649531246 SVTVVEDDEDEDGDDLLHHHHVSGSR ddPTM_HeLa_Curcumin_4h_R1 2 SVTVVEDDEDEDGDDLLHHHHVSGSR 26 0 P02545-2;Q3BDU5;Q5TCI8 P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 111.35 6.74E-07 74267000 3479.5 2711.48 2687.7 2234 3838.2 5188 2874.4 2234.73 4210.2 3508.7 FALSE FALSE TRUE 3204.093903 2945.848249 2787.308526 2224.7563 3792.431972 4111.950319 2955.047928 2916.08889 3748.351593 3630.627064 0.882518046 0.81138828 0.767720969 0.61277467 1.044566656 1.132573037 0.813922189 0.803191525 1.032425399 1 11.82600303 -8.68110091 0.934547738 0.98976864 0.861361362 0.166233543 0.137416791 0.877077586 1.53878265 0.061218399 0.029409116 2.08E-09 8.68110091 -0.128407278 SVVS(ph)DLEADDVK ddPTM_HeLa_Curcumin_4h_R1 4 SVVSDLEADDVK 12 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 S(0.046)VVS(0.954)DLEADDVK;SVVS(1)DLEADDVK;SVVS(1)DLEADDVK;SVVS(1)DLEADDVK ;;; 212.11 5.99E-10 137136000 14492.1 9497.6 13983.3 16122.5 17152.7 14724.7 12915.6 9123 13644.8 11168.6 TRUE FALSE FALSE 13345.03499 10318.53022 14501.5334 16055.78937 16948.16526 11670.63124 13277.97698 11904.5607 12147.99958 11556.70802 1.154743632 0.892860684 1.254815245 1.389304752 1.466521887 1.009857757 1.148941113 1.030099634 1.051164359 1 13.49644288 -8.418331821 0.505739194 1.000097225 1.193993544 0.125421787 0.161934556 1.520052907 0.819820855 0.13234534 0.053827254 3.82E-09 8.418331821 0.193896319 SVVS(ph)FDKVKEPR ddPTM_HeLa_Curcumin_4h_R1 1 SVVSFDKVKEPR 12 2 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 0 S(0.038)VVS(0.962)FDKVKEPR 81.185 0.017 546650000 4779.3 4832.2 3305.3 4788.4 4482.4 5270 5137.1 1636.2 5272.6 5921.6 TRUE FALSE FALSE 4401.013362 5249.873836 3427.797326 4768.58687 4428.950308 4176.942595 5281.2332 2135.069848 4694.208971 6127.375159 0.718254268 0.856790012 0.559423446 0.778243007 0.722813634 0.681685467 0.861907924 0.348447711 0.766104384 1 12.58105347 -13.52287874 0.156236845 2.174179328 0.59869286 0.18290629 0.153190461 41.39389274 0.43510236 14.83609777 0.257747692 3.00E-14 13.52287874 -1.575486468 SVVSDLEADDVKGSVPLS(ph)SSPPATHFPDETEITNPVPK ddPTM_HeLa_Curcumin_4h_R1 1 SVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPK 38 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 SVVSDLEADDVKGS(0.002)VPLS(0.31)S(0.31)S(0.31)PPAT(0.062)HFPDET(0.003)EIT(0.003)NPVPK 82.554 7.42E-10 159460000 2426.8 1219.9 1880.9 2743.4 1640.5 2440.4 1771.8 1122.8 3072.1 1985.1 TRUE FALSE FALSE 2234.716219 1325.34272 1950.607809 2732.048538 1620.938109 1934.233531 1821.511939 1465.136551 2735.098316 2054.082077 1.087939106 0.645223837 0.949625056 1.330058116 0.789130155 0.941653477 0.886776609 0.713280432 1.331542856 1 11.00427811 -3.301493239 0.583151657 1.018385152 3.34E-15 0.200770697 0.19735796 10.93517213 1.11987494 0.030681359 9.731991798 0.000499467 3.301493239 -1.018385152 SVVSDLEADDVKGSVPLSS(ph)SPPATHFPDETEITNPVPK ddPTM_HeLa_Curcumin_4h_R1 1 SVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPK 38 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 SVVSDLEADDVKGS(0.006)VPLS(0.111)S(0.336)S(0.336)PPAT(0.111)HFPDET(0.05)EIT(0.05)NPVPK 66.004 3.86E-06 190650000 4013 2005.6 3434.4 5263.7 3707.1 4438.7 3817.7 2056.2 5672.7 4216.6 TRUE FALSE FALSE 3695.366816 2178.955127 3561.681885 5241.920204 3662.895254 3518.063586 3924.814387 2683.125914 5050.419002 4363.126536 0.846953849 0.499402231 0.81631414 1.201413748 0.83951158 0.806317111 0.899541729 0.614954871 1.157522928 1 12.0911466 -8.745574416 1.066132351 0.984806362 0.82587806 0.215077256 0.181790783 0.757544123 1.721730186 0.068684376 0.03413525 1.80E-09 8.745574416 -0.158928301 SVVSDLEADDVKGSVPLSSSPPATHFPDET(ph)EITNPVPK ddPTM_HeLa_Curcumin_4h_R1 1 SVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPK 38 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 SVVSDLEADDVKGS(0.003)VPLS(0.113)S(0.113)S(0.113)PPAT(0.113)HFPDET(0.484)EIT(0.06)NPVPK 62.183 5.52E-05 3695400 1198.4 561.19 946.99 1298.9 972.58 1147.5 1250.8 539.81 1429.9 1057 TRUE FALSE FALSE 1103.545375 609.696763 982.0862825 1293.525496 960.9826187 909.495565 1285.894082 704.395584 1273.043547 1093.730671 1.008973602 0.557446892 0.897923326 1.182672782 0.878628207 0.831553497 1.175695366 0.644030201 1.163946098 1 10.09504181 SVVTSIFGVK ddPTM_HeLa_Curcumin_4h_R1 2 SVVTSIFGVK 10 0 J3KR24;A0A0A0MSX9;P41252 J3KR24 IARS "Isoleucine--tRNA ligase, cytoplasmic" 0 0 ; ; 164.68 3.66E-10 1248860 1217.43 933.61 1153.75 1225.95 1048.69 1132.53 945.56 1154.26 1188.78 1025.11 FALSE FALSE TRUE 1121.069131 1014.307088 1196.50899 1220.877344 1036.185057 897.6305118 972.0898688 1506.18856 1058.373808 1060.732496 1.056882046 0.95623269 1.128002578 1.150975715 0.97685803 0.846236459 0.916432628 1.419951369 0.997776359 1 10.05084516 SVWGSLAVQNS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 SVWGSLAVQNSPK 13 0 P18615;P18615-3;P18615-4 P18615 NELFE Negative elongation factor E 1 0 SVWGSLAVQNS(1)PK 92.939 0.010663 114860000 3417.9 2712.2 2708.6 2851.2 2961.1 3931.8 3698.3 1099 3531.5 2836 TRUE FALSE FALSE 3147.369608 2946.630483 2808.983099 2839.40249 2925.790816 3116.300359 3802.064345 1434.080041 3144.103285 2934.550789 1.072521771 1.004116369 0.957210592 0.967576537 0.997014885 1.061934376 1.295620563 0.488688097 1.071408713 1 11.51892396 -4.24342901 24.91533893 1.035727741 0.488687615 0.766059674 0.092434839 1360.885544 1882604.184 0.012306436 0.537959965 5.71E-05 4.24342901 -0.547040126 SVYAT(ph)MGDHENRSPVKEPVEQPR ddPTM_HeLa_Curcumin_4h_R1 1 SVYATMGDHENRSPVKEPVEQPR 23 2 Q96T58 Q96T58 SPEN Msx2-interacting protein 1 0 S(0.008)VY(0.065)AT(0.702)MGDHENRS(0.224)PVKEPVEQPR 47.603 0.0094635 26844000 6164.2 4877.3 4767.6 5352 6272.4 7331.4 5229.2 2297 6261.6 5295.3 TRUE FALSE FALSE 5676.297066 5298.872079 4944.29145 5329.854842 6197.605727 5810.784998 5375.917278 2997.344726 5574.718146 5479.311281 1.035950829 0.967069 0.902356372 0.972723499 1.131092104 1.060495508 0.98113011 0.547029466 1.0174122 1 12.41977885 -4.263252021 4.632502499 1.013159586 0.519015105 0.853376132 0.057378379 0.051732517 2.955728997 0.008302392 0.082501586 5.45E-05 4.263252021 -0.494144481 SWDEEEEDEYDYFVR ddPTM_HeLa_Curcumin_4h_R1 3 SWDEEEEDEYDYFVR 15 0 Q8NEM2;I3L3Z1 Q8NEM2 SHCBP1 SHC SH2 domain-binding protein 1 0 0 ;; ;; 216.91 2.32E-13 22794300 5644.88 3789.92 4323.61 4380.1 4616.3 5026.7 3832.41 4378.38 4975.7 4265.81 FALSE FALSE TRUE 5198.081792 4117.503797 4483.84679 4361.976307 4561.253638 3984.105757 3939.93711 5713.327906 4429.878159 4414.04658 1.177622777 0.932818384 1.015813202 0.988203506 1.033349684 0.902597126 0.892590742 1.294351521 1.003586636 1 12.10788614 -7.250169205 24.96041627 1.083877424 1.000451032 0.025387601 0.116575921 1306.499573 2893550.621 0.019582864 0.023863734 5.62E-08 7.250169205 -0.083426392 KSYESSEDCSEAAGS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 3 KSYESSEDCSEAAGSPAR 18 1 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 0 KSYESSEDCSEAAGS(1)PAR;KSYESSEDCSEAAGS(1)PAR;KSYESSEDCS(0.001)EAAGS(0.999)PAR ;; 185.06 1.43E-07 256065000 18729 15188.1 15900.2 16883.6 16502.2 18823 14300.2 4806.3 18824.4 15834.9 TRUE FALSE FALSE 17246.57989 16500.89169 16489.4754 16813.74014 16305.42204 14918.89762 14701.42512 6271.718745 16759.41042 16385.1616 1.052573073 1.007063103 1.006366358 1.026156504 0.995133429 0.910512694 0.897240167 0.382768196 1.022840716 1 14.00010228 -4.117102839 1.597040942 1.017734763 6.05E-19 0.967079907 0.034172142 0.19157963 0.346247558 0.005226445 0.335696696 7.64E-05 4.117102839 -1.017734763 down FLSLEYS(ph)PAGK ddPTM_HeLa_Curcumin_4h_R1 1 FLSLEYSPAGK 11 0 Q9C0H5;Q9C0H5-2 Q9C0H5 ARHGAP39 Rho GTPase-activating protein 39 1 0 FLSLEYS(1)PAGK 92.112 0.015904 8726200 1784.8 1391.8 1928.4 1501.8 1610.9 1643.1 1294.6 482.69 1593.5 1565.6 TRUE FALSE FALSE 1643.531197 1512.10099 1999.8682 1495.58595 1591.69107 1302.302538 1330.922992 629.859959 1418.697037 1620.004483 1.014522622 0.93339309 1.234483127 0.923198648 0.982522632 0.803888231 0.821555129 0.388801368 0.875736488 1 10.66178209 -4.116731595 0.961651261 1.012811061 1.52E-15 0.757446867 0.101017516 0.737877183 0.432334016 0.012822469 0.825482451 7.64E-05 4.116731595 -1.012811061 down LSTEADTDT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 LSTEADTDTPK 11 0 Q9BYW2;H7C3H4;A0A1W2PPX9 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 0 LSTEADT(0.002)DT(0.998)PK;LSTEADT(0.428)DT(0.571)PK ; 152.38 0.001423 24589800 5478.4 5253.3 6384.8 6433.7 5846.2 5760.9 4577.8 1642.62 6595.4 5323 TRUE FALSE FALSE 5044.778859 5707.371844 6621.426305 6407.079054 5776.487883 4566.024401 4706.240747 2143.447276 5871.901121 5507.973854 0.915904649 1.036201695 1.202152821 1.163237013 1.048750055 0.8289844 0.854441374 0.389153495 1.066072802 1 12.427306 -4.116622592 1.370638352 1.00049842 1.54E-14 0.786381005 0.101438864 0.731320099 0.934135164 0.016896554 1.10557424 7.64E-05 4.116622592 -1.00049842 down SWEDS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 SWEDSPER 8 0 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;A0A3B3IRI3;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISZ5;Q9UDY2-5;A0A3B3IRV6;A0A3B3ISF1;A0A3B3IU26;B1AN86 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 S(0.029)WEDS(0.971)PER 101.97 0.013897 152130000 3984.1 3462.1 3421 3607.2 3706.1 4511.1 2922.3 2946.9 3829.1 3329.8 TRUE FALSE FALSE 3668.754281 3761.348497 3547.785269 3592.274362 3661.907178 3575.447009 3004.291873 3845.396244 3409.05731 3445.510302 1.064792718 1.091666594 1.029683547 1.04259574 1.062805465 1.037711891 0.871943953 1.116060005 0.989420147 1 11.75050196 -4.937077573 24.99976971 1.039093975 0.98420851 0.076790545 0.061701975 95.76853136 38048.22198 0.007772548 0.023317644 1.16E-05 4.937077573 -0.054885465 SWEEPNWMGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 SWEEPNWMGSPR 12 0 B0QY95;Q9NQG6-2;Q9NQG6 B0QY95 MIEF1 Mitochondrial dynamics protein MID51 1 0 SWEEPNWMGS(1)PR 86.467 0.018506 3169000 1743.6 1471.3 1261.1 1844.4 1642.1 1031.1 949.34 839.1 2031.8 1463.1 TRUE FALSE FALSE 1605.59222 1598.472616 1307.837475 1836.768362 1622.51903 817.2382371 975.9759254 1094.937727 1808.916623 1513.942616 1.06053704 1.055834349 0.863861986 1.213235127 1.071717655 0.539807935 0.644658467 0.723235951 1.194838301 1 10.56409481 -5.266762477 24.99212545 1.035318188 0.636776546 0.78084846 0.103473583 127.286208 597614.2068 0.012441725 0.028601868 5.41E-06 5.266762477 -0.398541643 SWQQTTFQNRPDS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 SWQQTTFQNRPDSR 14 1 Q9BYW2;H7C3H4;C9JG86;Q9BYW2-3;Q9BYW2-2;H7BZ93;H7BXT4 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 0 SWQQTTFQNRPDS(1)R 95.236 0.0069193 0 1173.6 935.21 1082.4 1078.6 1006.8 876.27 739.89 404.05 1027.3 873.85 TRUE FALSE FALSE 1080.708322 1016.045385 1122.514696 1074.137039 994.7945676 694.5217244 760.6493221 527.242985 914.6077602 904.2162225 1.195187937 1.123675245 1.241422868 1.187920557 1.100173325 0.768092528 0.841225034 0.583093924 1.011492315 1 9.820523991 -5.239552532 3.769611698 1.117022374 0.731340844 0.790890002 0.092557977 0.089089749 2.802554254 0.015018225 0.039235171 5.76E-06 5.239552532 -0.38568153 SWS(ph)LATFR ddPTM_HeLa_Curcumin_4h_R1 2 SWSLATFR 8 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 1 0 SWS(1)LATFR;SWS(1)LATFR ; 114.4 0.010009 21159300 2317.21 2326.1 2229.18 2538.3 2143 3982.6 4815.9 4244.4 3661.2 2801.3 TRUE FALSE FALSE 2133.800383 2527.157719 2311.795372 2527.797187 2117.446125 3156.563867 4951.021193 5538.498021 3259.57552 2898.644966 0.736137198 0.871841067 0.797543472 0.872061676 0.730495162 1.088979128 1.708046777 1.910719693 1.124516992 1 11.50116292 -4.779170462 2.650902733 0.85787715 1.886512223 0.912842144 0.114324295 0.048526838 0.667926143 0.015134234 0.068340157 1.66E-05 4.779170462 1.028635073 SWS(ph)SEEESNQATGTSR ddPTM_HeLa_Curcumin_4h_R1 1 SWSSEEESNQATGTSR 16 0 F6UZG9;Q8NFZ0;Q8NFZ0-2 F6UZG9 FBXO18 F-box only protein 18 1 0 S(0.167)WS(0.71)S(0.122)EEESNQATGTSR 113.14 0.0013902 15288000 915.68 885 807.58 1108 937.64 1183.7 702.52 428.16 1187.1 852.14 TRUE FALSE FALSE 843.2029618 961.4954565 837.5096252 1103.41539 926.4592554 938.187277 722.2308205 558.704013 1056.8781 881.7518016 0.95628153 1.090437757 0.949824683 1.251390003 1.050702991 1.064003811 0.8190863 0.633629568 1.198611784 1 9.784228808 -4.516371917 3.045288963 1.013669324 0.643363817 0.619116759 0.104890661 0.128116589 2.219278363 0.012908475 0.084704665 3.05E-05 4.516371917 -0.370305508 TAQALSS(ph)GSGSQETKIPISLVLR ddPTM_HeLa_Curcumin_4h_R1 1 TAQALSSGSGSQETKIPISLVLR 23 1 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 0 TAQALS(0.044)S(0.501)GS(0.097)GS(0.355)QET(0.003)KIPISLVLR 91.655 7.30E-05 63072000 1361.5 944.75 1055.1 970.03 958.01 1675.4 1028.3 1466.2 1236.6 890.1 TRUE FALSE FALSE 1253.735838 1026.40998 1094.202934 966.0162729 946.5863564 1327.903154 1057.15133 1913.23763 1100.948074 921.0309087 1.361231015 1.114414262 1.188019776 1.048842404 1.027746569 1.441757428 1.147791372 2.07727842 1.195343243 1 9.847105762 -2.335424067 1.401786751 1.161725324 199.9999999 0.786868993 0.140067086 124.3038073 1.42520398 0.023819961 78373.21991 0.004619297 2.335424067 198.8382745 up DSSPSSS(ph)PSPK ddPTM_HeLa_Curcumin_4h_R1 1 DSSPSSSPSPK 11 0 E7EX40;Q6WKZ4-2;Q6WKZ4-3;Q6WKZ4 E7EX40 RAB11FIP1 Rab11 family-interacting protein 1 1 0 DSSPS(0.035)S(0.201)S(0.719)PS(0.044)PK 97.779 0.012445 7456500 3235 3104.7 3927.9 3655.2 4283.4 4642.5 3847.7 7058.8 3349.2 2945.7 TRUE FALSE FALSE 2978.946336 3373.056434 4073.471429 3640.075751 4232.323253 3679.593168 3955.656106 9210.995625 2981.801139 3048.062856 0.977324444 1.106622991 1.336413198 1.194225947 1.388528863 1.207190712 1.297760674 3.021917874 0.97826104 1 11.57367694 -2.292173716 1.171313348 1.060581512 199.9999999 0.921848514 0.160669736 31.61063056 0.541775701 0.026989552 16394.09447 0.005103008 2.292173716 198.9394184 up SWSYNGYYS(ph)DLSTAR ddPTM_HeLa_Curcumin_4h_R1 2 SWSYNGYYSDLSTAR 15 0 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 0 SWSYNGYY(0.001)S(0.997)DLS(0.002)TAR;SWSYNGY(0.021)Y(0.068)S(0.909)DLS(0.001)T(0.001)AR ; 108.25 0.0024141 15015200 3674.6 2149.9 2269.1 2394.2 2844.8 6675.3 2786.6 2731.4 2891 1957.94 TRUE FALSE FALSE 3383.751533 2335.727776 2353.194842 2384.293435 2810.877618 5290.767534 2864.784496 3564.191286 2573.864533 2025.978269 1.670181553 1.15288886 1.161510406 1.17686032 1.387417457 2.611463121 1.414025283 1.759244578 1.270430474 1 10.98440298 -3.639829598 0.050855441 6.63E-13 3.624520278 0.239299318 0.387908982 284.639285 1.925723049 43.97564435 104.1862607 0.000229177 3.639829598 3.624520278 SWVIGS(ph)PEILR ddPTM_HeLa_Curcumin_4h_R1 1 SWVIGSPEILR 11 0 Q6P0Q8;Q6P0Q8-2;A0A669KBJ4;E7ERL6 Q6P0Q8 MAST2 Microtubule-associated serine/threonine-protein kinase 2 1 0 S(0.176)WVIGS(0.824)PEILR 107.39 0.0076776 75626000 2598.9 2290.6 2186.5 2595.5 2379.6 2416.3 1889.8 1004.1 2911.2 2001 TRUE FALSE FALSE 2393.194323 2488.589257 2267.533613 2584.760509 2351.224824 1915.132143 1942.822702 1310.245468 2591.848643 2070.534601 1.155834016 1.201906626 1.095144033 1.248354173 1.135564131 0.924945732 0.93831936 0.632805396 1.251777508 1 11.0157876 -4.204634888 1.153309222 1.101173251 0.383675778 0.739135766 0.092449761 0.771335677 0.76191264 0.014363002 0.686100037 6.24E-05 4.204634888 -0.717497473 SY(ph)T(ph)S(ph)KKS(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 SYTSKKSSK 9 2 H3BPM9;Q9Y3E1 H3BPM9 HDGFRP3 Hepatoma-derived growth factor-related protein 3 4 0 S(0.597)Y(0.678)T(0.741)S(0.985)KKS(0.879)S(0.121)K 54.023 0.019435 9294600 3235.9 3314.9 3330.6 3273 3249.3 4026.3 2478.5 2492.4 3007.9 2990.7 TRUE FALSE FALSE 2979.7751 3601.425185 3454.034966 3259.457193 3210.55422 3191.199994 2548.040039 3252.321286 2677.940895 3094.626602 0.962886798 1.16376728 1.116139493 1.053263483 1.037460939 1.031206799 0.823375601 1.05095758 0.865351863 1 11.59554963 -3.945659636 22.36649122 1.004577007 1.812585394 0.018492264 0.097941419 5345.617124 1554623.116 0.012313414 357830.1996 0.000113329 3.945659636 0.808008387 SYCAEIAHNVSSK ddPTM_HeLa_Curcumin_4h_R1 2 SYCAEIAHNVSSK 13 0 D3YTB1;F8W727;P62910 D3YTB1 RPL32 60S ribosomal protein L32 0 0 ; ; 158.34 2.54E-05 14594100 11198.7 9195.3 8896.7 8401.6 12514.6 17034.3 9859.1 9477.8 13482.7 9608.6 FALSE FALSE TRUE 10312.31108 9990.100759 9226.419528 8366.836405 12365.37157 13501.19416 10135.71981 12367.53759 12003.68154 9942.498135 1.037195174 1.004787793 0.927977999 0.841522552 1.243688598 1.357927754 1.019433916 1.243906453 1.207310414 1 13.27939267 -5.738055808 24.99994895 0.998440486 1.212302361 0.445997478 0.116253376 139.0514375 148662.489 0.01382904 0.027645044 1.83E-06 5.738055808 0.213861875 SYEALVQHVIEDHER ddPTM_HeLa_Curcumin_4h_R1 2 SYEALVQHVIEDHER 15 0 Q9H2P0;A0A669KBJ7;A0A2R8Y6X0 Q9H2P0 ADNP Activity-dependent neuroprotector homeobox protein 0 0 ; ; 137.93 0.0001674 5563500 3183.36 3192.46 3181.85 3324.98 3286.46 4352.6 2727.32 2731.93 3825.7 3057.37 FALSE FALSE TRUE 2931.393697 3468.402017 3299.77216 3311.222114 3247.271111 3449.821696 2803.841259 3564.882881 3406.030281 3163.61338 0.926596693 1.096341936 1.043039008 1.046658272 1.026443728 1.090468803 0.886278101 1.126838982 1.076626589 1 11.62735759 -7.269768192 24.9789066 0.965337328 1.040042093 0.001259034 0.07225988 643.1472751 1928856.689 0.010419883 0.012015934 5.37E-08 7.269768192 0.074704765 SYEDDDDMDLQPNK ddPTM_HeLa_Curcumin_4h_R1 1 SYEDDDDMDLQPNK 14 0 Q9BTE3;Q9BTE3-2 Q9BTE3 MCMBP Mini-chromosome maintenance complex-binding protein 0 0 186.74 0.00017508 10429000 1343.6 1348 1237.5 1639.2 1356.8 1372.4 1352.6 1282.5 1484.6 1364.4 FALSE FALSE TRUE 1237.252642 1464.515113 1283.362839 1632.417425 1340.621046 1087.74877 1390.550316 1673.528346 1321.743094 1411.812798 0.876357435 1.037329535 0.909017711 1.156256287 0.949574227 0.770462466 0.984939588 1.185375531 0.9362028 1 10.46333309 -7.247573516 24.69057339 0.94161323 0.990350622 0.052785539 0.114943844 2123.238623 3780796.296 0.019796934 0.024180044 5.65E-08 7.247573516 0.048737392 SYELPDGQVIT(ph)IGNER ddPTM_HeLa_Curcumin_4h_R1 1 SYELPDGQVITIGNER 16 0 P60709;A0A2R8Y793;P63267-2;Q6S8J3;A5A3E0;A0A2R8YEA7;Q562R1;Q9BYX7;P63261;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;ACTG2;POTEE;POTEF;ACTBL2;POTEKP;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Beta-actin-like protein 2;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 1 0 S(0.002)Y(0.001)ELPDGQVIT(0.997)IGNER 139.39 0.0011586 36922000 4926.8 3790.1 4691.1 4661.8 5300.3 5936.2 3882.5 2702.2 5043.3 4073.5 TRUE FALSE FALSE 4536.838581 4117.699356 4864.956293 4642.510707 5237.097384 4704.965205 3991.432501 3526.088341 4490.062608 4215.053822 1.076341791 0.97690315 1.154186043 1.101411964 1.242474617 1.116228975 0.946946983 0.836546457 1.06524443 1 12.04133534 -4.531093286 3.833978634 1.064464306 0.851499603 0.528997558 0.075134836 0.152463428 4.809080785 0.011839548 0.062752558 2.94E-05 4.531093286 -0.212964703 SYELPDGQVITIGNER ddPTM_HeLa_Curcumin_4h_R1 8 SYELPDGQVITIGNER 16 0 P60709;A0A2R8Y793;P63267-2;Q6S8J3;A5A3E0;A0A2R8YEA7;Q562R1;Q9BYX7;P63261;P68133;P68032;P63267;P62736 P60709;P63261;P68133 ACTB;ACTG2;POTEE;POTEF;ACTBL2;POTEKP;ACTG1;ACTA1;ACTC1;ACTA2 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, gamma-enteric smooth muscle;POTE ankyrin domain family member E;POTE ankyrin domain family member F;Beta-actin-like protein 2;Putative beta-actin-like protein 3;Putative beta-actin-like protein 3, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed;Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, aortic smooth muscle" 0 0 ;;;;;;; ;;;;;;; 356.59 7.03E-172 1316161700 25253.49 21456.99 21613.71 23473.53 20698.27 28059.02 21239.53 21847.09 26296.94 23185.58 FALSE FALSE TRUE 23254.64962 23311.63661 22414.73311 23376.40275 20451.45665 22239.26296 21835.45405 28508.16717 23412.23147 23991.27718 0.969296026 0.971671347 0.93428678 0.974370917 0.852453852 0.926972866 0.910141377 1.188272177 0.975864323 1 14.55022234 -8.320633696 0.796616301 0.996460945 0.957235913 0.002216179 0.08304947 1.698815278 2.291520516 0.031043254 0.01800014 4.78E-09 8.320633696 -0.039225032 SYEPLEDPGVK ddPTM_HeLa_Curcumin_4h_R1 2 SYEPLEDPGVK 11 0 F2Z393;P37837 F2Z393 TALDO1 Transaldolase 0 0 ; ; 139.98 6.98E-05 6738100 7381.8 6849.3 7245.1 7253.2 7594.1 7995.6 7240.1 6225.8 7874.3 7109.6 FALSE FALSE TRUE 6797.522741 7441.322972 7513.609779 7223.18818 7503.545317 6337.222431 7443.23772 8124.01776 7010.508991 7356.658071 0.923996015 1.011508609 1.021334648 0.981857266 1.019966572 0.861426801 1.011768883 1.10430819 0.95294751 1 12.84483482 -7.224869618 24.90179897 0.964109212 0.997417964 0.094774977 0.058879536 1320.858974 899426.0237 0.010273968 0.012582773 5.96E-08 7.224869618 0.033308753 SYES(ph)SEDCSEAAGSPAR ddPTM_HeLa_Curcumin_4h_R1 2 SYESSEDCSEAAGSPAR 17 0 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 0 S(0.001)YES(0.985)S(0.014)EDCSEAAGSPAR;S(0.002)YES(0.499)S(0.499)EDCSEAAGSPAR ; 258.12 8.92E-41 14578100 5297.3 4781.2 5218.6 5303.7 5075.4 4939.8 3528.3 3776.3 5428.9 4635.3 TRUE FALSE FALSE 4878.013115 5194.465623 5412.005907 5281.754695 5014.87917 3915.229797 3627.294602 4927.676486 4833.363252 4796.37633 1.017020513 1.082997927 1.12835306 1.101196889 1.045555816 0.816289117 0.756257298 1.027374865 1.00771143 1 12.22772914 -5.266716097 24.66356555 1.032562083 0.85560211 0.542450902 0.077096973 214.9387452 1004634.5 0.011236483 0.025848685 5.41E-06 5.266716097 -0.176959973 SYESSEDCSEAAGS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 2 SYESSEDCSEAAGSPAR 17 0 Q6P6C2-3;Q6P6C2;K7ER58 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 0 SYESSEDCS(0.011)EAAGS(0.989)PAR;SYESSEDCSEAAGS(1)PAR ; 278.79 1.19E-65 65416000 2253.7 1824.3 2087.2 2053 1665.55 2605.3 2153.08 505.84 2258.8 1742.54 TRUE FALSE FALSE 2075.317267 1981.984363 2164.553468 2044.50523 1645.689404 2064.931412 2213.48963 660.0682874 2011.015291 1803.093135 1.15097619 1.099213526 1.200466812 1.133887757 0.912703494 1.145216169 1.227606931 0.366075537 1.115314152 1 10.8162582 -4.254720544 24.99998744 1.089439056 0.36607521 0.860136855 0.089605257 226.2667016 841889.5384 0.013310901 0.17278441 5.56E-05 4.254720544 -0.723363846 SYETLVDFDNHLDDIR ddPTM_HeLa_Curcumin_4h_R1 2 SYETLVDFDNHLDDIR 16 0 M0R1B0;O43402 M0R1B0 EMC8 ER membrane protein complex subunit 8 0 0 ; ; 162.79 0.00019291 10259800 2498.55 1961.95 2459.64 2127.17 2855 3114.11 2198.77 2333.35 2675.64 2418.92 FALSE FALSE TRUE 2300.787131 2131.532216 2550.796422 2118.368334 2820.95599 2468.208483 2260.461569 3044.777674 2382.128986 2502.97729 0.919220138 0.851598704 1.019104901 0.846339415 1.127040186 0.98610902 0.9031091 1.216462365 0.951718178 1 11.28942949 -5.754637897 24.99999947 0.949329065 1.0419557 0.286767444 0.094125328 206.8815997 760421.4201 0.013104594 0.025738892 1.76E-06 5.754637897 0.092626635 SYLEGS(ph)S(ph)DNQLKDSESTPVDDR ddPTM_HeLa_Curcumin_4h_R1 2 SYLEGSSDNQLKDSESTPVDDR 22 1 Q9UHI6;E9PJ60 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 2 0 S(0.007)Y(0.006)LEGS(0.993)S(0.993)DNQLKDS(0.001)ESTPVDDR;S(0.011)Y(0.01)LEGS(0.983)S(0.983)DNQLKDS(0.009)ES(0.002)T(0.002)PVDDR ; 77.668 0.00078317 29807000 6771.6 5220.2 5833.3 5961.9 6222.3 5570.4 3173 2333.9 5833.5 5121.3 TRUE FALSE FALSE 6235.620715 5671.410827 6049.487229 5937.231237 6148.103136 4415.036249 3262.02584 3045.495366 5193.579645 5299.264794 1.176695439 1.070225974 1.141571041 1.120387727 1.160180398 0.833141279 0.615561963 0.574701489 0.980056639 1 12.3715765 -4.981760972 2.644724132 1.09584651 0.587679397 0.909471861 0.063294311 0.062407801 0.867595152 0.010442931 0.037175859 1.04E-05 4.981760972 -0.508167112 SYLEGS(ph)SDNQLKDSESTPVDDR ddPTM_HeLa_Curcumin_4h_R1 1 SYLEGSSDNQLKDSESTPVDDR 22 1 Q9UHI6;E9PJ60 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 1 0 S(0.001)Y(0.001)LEGS(0.553)S(0.444)DNQLKDSESTPVDDR 98.443 6.49E-05 50358000 1489.8 1195.6 1342.4 1477.3 1360.8 1174.7 752.8 640.27 1370.3 1113.9 TRUE FALSE FALSE 1371.880758 1298.942337 1392.150525 1471.187324 1344.573349 931.0539784 773.9215419 835.4853756 1219.981518 1152.607942 1.190240591 1.126959384 1.207826594 1.276398739 1.166548745 0.807780291 0.67145255 0.724865191 1.05845316 1 10.17068615 -5.145942892 3.872929451 1.122387469 0.706090875 0.856628735 0.077444534 0.084467029 2.225242966 0.014559333 0.040003246 7.15E-06 5.145942892 -0.416296594 SYLEGSS(ph)DNQLKDSESTPVDDR ddPTM_HeLa_Curcumin_4h_R1 3 SYLEGSSDNQLKDSESTPVDDR 22 1 Q9UHI6;E9PJ60 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 1 0 SYLEGS(0.147)S(0.853)DNQLKDSESTPVDDR;SYLEGS(0.045)S(0.954)DNQLKDSESTPVDDR;S(0.001)YLEGS(0.211)S(0.787)DNQLKDSESTPVDDR ;; 113.23 6.60E-06 152422000 5751.4 5316 5694.4 5373.2 5170.7 5737.3 2828.05 2396.96 5478.2 5158.5 TRUE FALSE FALSE 5296.170621 5775.491352 5905.439473 5350.967122 5109.04278 4547.319307 2907.397472 3127.78207 4877.255166 5337.757491 0.992208925 1.082007072 1.106352149 1.002474753 0.957151536 0.851915681 0.544685193 0.585973056 0.91372738 1 12.38201805 -4.935190483 2.11234235 1.010816856 0.547579647 0.908179349 0.055478718 0.058554389 0.503604311 0.007208019 0.03083857 1.16E-05 4.935190483 -0.463237209 GPSPAPAS(ph)SPKR ddPTM_HeLa_Curcumin_4h_R1 1 GPSPAPASSPKR 12 1 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 1 0 GPSPAPAS(0.5)S(0.5)PKR 88.78 0.0076395 15549000 2696.3 2050.2 2368.3 2605 3226.6 3787 3351.5 6362.9 2814.9 2237.9 TRUE FALSE FALSE 2482.88501 2227.410152 2456.071281 2594.2212 3188.124902 3001.533512 3445.53407 8302.918919 2506.112513 2315.666858 1.072211662 0.961887132 1.060632393 1.120291199 1.376763195 1.296185373 1.487923039 3.585541197 1.082242251 1 11.177212 -2.240977049 1.073172474 1.052818836 200 0.971434951 0.12590216 14.1095058 0.261574481 0.019590027 6650.750927 0.005741468 2.240977049 198.9471812 up SYNPFDDDGEDEGARPAPWR ddPTM_HeLa_Curcumin_4h_R1 2 SYNPFDDDGEDEGARPAPWR 20 1 O95721 O95721 SNAP29 Synaptosomal-associated protein 29 0 0 ; ; 129.89 7.01E-05 21238200 2848.2 2239.08 2738.3 2425.7 2514.1 3933.4 2601.6 2376.6 2844.9 2699.8 FALSE FALSE TRUE 2622.761965 2432.616098 2839.783807 2415.663096 2484.121 3117.568501 2674.593894 3101.214399 2532.821588 2793.617849 0.938840638 0.870776258 1.016525509 0.864707783 0.889212889 1.115960976 0.957394332 1.110106882 0.906645692 1 11.44791897 -5.261808184 24.9997798 0.9533617 1.050778088 0.426989731 0.066213469 30.11965121 2041747.953 0.009237875 0.021911917 5.47E-06 5.261808184 0.097416388 SYQNSPS(ph)S(ph)DDGIRPLPEYSTEK ddPTM_HeLa_Curcumin_4h_R1 1 SYQNSPSSDDGIRPLPEYSTEK 22 1 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 2 0 S(0.025)Y(0.021)QNS(0.117)PS(0.872)S(0.906)DDGIRPLPEY(0.031)S(0.014)T(0.014)EK 50.916 0.019665 41587000 1128.2 709.09 1135.2 1306.4 957.66 1399.8 1093.2 911.81 1300.5 936.68 TRUE FALSE FALSE 1038.90178 770.38058 1177.271511 1300.994463 946.24053 1109.465701 1123.87225 1189.816672 1157.838404 969.2295603 1.071884125 0.794838098 1.214646724 1.342297549 0.97628113 1.144688262 1.15955218 1.227590161 1.194596668 1 9.920694596 SYQNSPS(ph)SDDGIRPLPEYSTEK ddPTM_HeLa_Curcumin_4h_R1 1 SYQNSPSSDDGIRPLPEYSTEK 22 1 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 0 SYQNS(0.025)PS(0.758)S(0.217)DDGIRPLPEYSTEK 107.06 1.67E-05 9738700 1326 1296 1299.1 1661.7 1183.3 1738.9 1173.2 1569.4 1668.5 1123.3 TRUE FALSE FALSE 1221.045701 1408.020465 1347.245789 1654.824326 1169.18992 1378.232539 1206.116834 2047.902835 1485.469724 1162.334591 1.050511367 1.211372763 1.159086031 1.423707371 1.005897896 1.185745093 1.037667504 1.761887541 1.278005262 1 10.18280971 -4.25911437 24.83920049 1.082757391 1.761887801 0.592785354 0.142538469 85.74395117 915978.3079 0.01919192 0.172008055 5.51E-05 4.25911437 0.67913041 SYQNSPSS(ph)DDGIRPLPEYSTEK ddPTM_HeLa_Curcumin_4h_R1 1 SYQNSPSSDDGIRPLPEYSTEK 22 1 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 0 SYQNS(0.043)PS(0.145)S(0.812)DDGIRPLPEYSTEK 110.38 1.13E-05 23125000 1522.5 1043.3 1436.4 1409.3 1495.3 1273.3 1114 1427.3 1347.5 1504.8 TRUE FALSE FALSE 1401.992518 1133.478203 1489.634248 1403.46869 1477.469524 1009.203227 1145.255842 1862.4772 1199.682621 1557.091688 0.900391756 0.727945703 0.956677284 0.901339787 0.94886482 0.648133462 0.735509573 1.196125581 0.770463699 1 10.60463818 -8.513866008 0.842008895 0.991549543 0.865908962 0 0.160741269 0.927383866 1.35421582 0.058574897 0.030121898 3.06E-09 8.513866008 -0.125640581 SYS(ph)LSELSVLQAK ddPTM_HeLa_Curcumin_4h_R1 1 SYSLSELSVLQAK 13 0 Q9P0V3-2;Q9P0V3 Q9P0V3-2 SH3BP4 SH3 domain-binding protein 4 1 0 S(0.033)YS(0.966)LSELSVLQAK 240.42 7.55E-27 209410000 2350.2 2084.3 2274.7 2215.7 2079.8 2872 2028 2007.9 2531.9 1865.3 TRUE FALSE FALSE 2164.17919 2264.457605 2359.002383 2206.53202 2054.999743 2276.314826 2084.900222 2620.099467 2254.156905 1930.119036 1.121267212 1.173221735 1.222205646 1.14321033 1.064701039 1.179364994 1.08019256 1.357480766 1.167884914 1 10.91447411 -13.52287875 0.131276998 0.404941928 1.235769006 0 0.092639608 54.63044399 0.507407193 8.385955564 0.259454699 3.00E-14 13.52287875 0.830827078 SYS(ph)PAHNR ddPTM_HeLa_Curcumin_4h_R1 5 SYSPAHNR 8 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 S(0.015)YS(0.985)PAHNR;S(0.005)YS(0.995)PAHNR;S(0.434)Y(0.029)S(0.538)PAHNR;S(0.257)YS(0.742)PAHNR;S(0.228)Y(0.004)S(0.768)PAHNR ;;;; 97.597 0.0077769 48095530 8538.86 10719.14 7607.73 6461.28 7767.36 11098.81 6563.46 10039.76 8881.76 9108.33 TRUE FALSE FALSE 7863.000221 11645.6547 7889.679166 6434.544935 7674.739305 8796.791697 6747.613023 13100.83661 7907.453149 9424.84379 0.834284408 1.23563371 0.837115112 0.682721653 0.814309444 0.933362069 0.715938977 1.390032228 0.839000977 1 13.20225299 -9.676411538 1.515248075 1.000325966 0.904918757 0 0.217472163 1.518984207 6.245369566 0.145488599 0.031972007 2.11E-10 9.676411538 -0.09540721 SYS(ph)PDGK ddPTM_HeLa_Curcumin_4h_R1 1 SYSPDGK 7 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 0 S(0.109)YS(0.891)PDGK 99.013 0.020322 1216900000 5567.2 8471.6 5960.7 4868.7 5559.6 5190.6 3832.6 2592.1 3642.1 5407 TRUE FALSE FALSE 5126.550246 9203.847355 6181.608786 4848.554609 5493.305401 4114.01105 3940.132441 3382.419357 3242.570742 5594.892848 0.916291051 1.645044437 1.10486634 0.866603658 0.981842825 0.735315432 0.704237337 0.604554806 0.579559043 1 12.44989479 -5.186415125 1.41813612 1.02482652 0.629030125 0.277256073 0.250560458 0.425157359 1.549958356 0.033693788 0.144189483 6.51E-06 5.186415125 -0.395796396 SYS(ph)PDGKES(ph)PSDK ddPTM_HeLa_Curcumin_4h_R1 2 SYSPDGKESPSDK 13 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 2 0 S(0.017)YS(0.983)PDGKES(0.5)PS(0.5)DK;S(0.017)YS(0.982)PDGKES(0.507)PS(0.494)DK ; 150.01 0.002206 73540000 16552.6 14646 16907.9 16432.8 16438 17729.5 17060.3 11047.3 18290.9 15572.7 TRUE FALSE FALSE 15242.44424 15911.93498 17534.52165 16364.80543 16241.98759 14052.20185 17538.9661 14415.57091 16284.43403 16113.85017 0.94592193 0.987469464 1.08816462 1.015573886 1.007952005 0.872057373 1.088440436 0.894607482 1.010586164 1 13.97601363 SYS(ph)PDGKESPSDK ddPTM_HeLa_Curcumin_4h_R1 2 SYSPDGKESPSDK 13 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 0 S(0.013)Y(0.005)S(0.98)PDGKES(0.002)PSDK;S(0.15)YS(0.85)PDGKESPSDK ; 139.77 0.0095864 219237000 8756.89 7806.81 7231.32 8009.58 7027.82 9427.2 8751.6 5621.81 9981.9 7805.9 TRUE FALSE FALSE 8063.772916 8481.59587 7499.319081 7976.43848 6944.017837 7471.892454 8997.146342 7335.873989 8886.910543 8077.154444 0.998343287 1.050072266 0.928460528 0.987530762 0.859710915 0.925064948 1.113900496 0.908225049 1.100252645 1 12.97963141 -6.746635141 24.9995889 1.003009904 0.957040242 0.189971126 0.071366528 416.7746982 703796.4638 0.00985336 0.013901017 1.79E-07 6.746635141 -0.045969662 AT(ph)KKLLDNS(ph)HLPATFKVSSS(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 1 ATKKLLDNSHLPATFKVSSSPQK 23 3 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 3 0 AT(0.99)KKLLDNS(0.861)HLPAT(0.227)FKVS(0.157)S(0.175)S(0.59)PQK 42.309 0.017512 59201000 2591.7 2031.2 2039.7 2194 2098.2 2735 1914.9 669 2186.6 2181.1 TRUE FALSE FALSE 2386.56421 2206.767877 2115.293076 2184.921809 2073.180335 2167.73017 1968.62694 872.9750203 1946.735451 2256.893063 1.057455601 0.977790181 0.937258885 0.968110473 0.918599277 0.960493081 0.872273026 0.386803892 0.862573191 1 11.14012235 -4.115283803 1.66057683 1.004743525 4.29E-16 0.879235768 0.061782039 0.274021658 0.539568784 0.007603903 0.490591161 7.67E-05 4.115283803 -1.004743525 down SYS(ph)S(ph)Y(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 SYSSYK 6 0 Q5JSG7;A0A669KA35;Q92824 REV__Q5JSG7 PCSK5 Proprotein convertase subtilisin/kexin type 5 3 0 S(0.322)Y(0.029)S(0.665)S(0.986)Y(0.999)K 46.994 0.0092307 0 13183 11347 11285 11613 11292 14293 9002.9 6055 13326 11680 TRUE FALSE FALSE 12139.55164 12327.78412 11703.23203 11564.94848 11157.35028 11328.47068 9255.497144 7901.141626 11864.17114 12085.87913 1.004440927 1.020015506 0.968339324 0.956897579 0.923172419 0.937331125 0.765810831 0.653749846 0.981655617 1 13.5610348 -3.592282654 0.619948258 1.002639192 8.84E-21 0.954530868 0.023934968 0.797324022 0.116964337 0.003817196 0.689116514 0.000255692 3.592282654 -1.002639192 SYS(ph)SPDITQAIQEEEK ddPTM_HeLa_Curcumin_4h_R1 1 SYSSPDITQAIQEEEK 16 0 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 0 SYS(0.91)S(0.09)PDITQAIQEEEK 250.38 5.53E-40 91286000 5238.2 3739.5 4186.2 4328.2 4102.9 4750.5 3902.5 4215.2 4853.7 4462.4 TRUE FALSE FALSE 4823.590943 4062.725717 4341.344255 4310.291055 4053.975597 3765.192751 4011.993647 5500.395076 4321.261253 4617.468068 1.044639805 0.879860057 0.940200168 0.933475011 0.877965053 0.815423668 0.868873068 1.191214535 0.935850815 1 12.17288627 -7.267826333 24.83611124 1.021079909 0.921421986 0.055560005 0.099580259 563.5638818 2191451.611 0.015720098 0.018203772 5.40E-08 7.267826333 -0.099657923 SYS(ph)SPDITQAIQEEEKR ddPTM_HeLa_Curcumin_4h_R1 4 SYSSPDITQAIQEEEKR 17 1 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 0 S(0.009)YS(0.986)S(0.004)PDITQAIQEEEKR;S(0.175)YS(0.792)S(0.032)PDITQAIQEEEKR;S(0.079)YS(0.913)S(0.007)PDITQAIQEEEKR;S(0.188)YS(0.794)S(0.018)PDITQAIQEEEKR ;;; 200.73 7.93E-11 1330414000 11486.3 9369 9504.9 10277.8 9856 11776.5 9284.2 10077.8 11075.4 10265.1 TRUE FALSE FALSE 10577.14723 10178.81461 9857.159955 10235.27319 9738.473637 9333.921151 9544.689665 13150.47483 9860.456329 10621.81146 0.995795046 0.958293663 0.928011196 0.963609006 0.916837366 0.878750408 0.898593399 1.238063289 0.928321536 1 13.37474221 -7.273073687 6.469826822 0.998075964 0.958891657 0 0.097781671 0.471285063 97.62863202 0.015305928 0.017897438 5.33E-08 7.273073687 -0.039184307 SYSEDDIHR ddPTM_HeLa_Curcumin_4h_R1 4 SYSEDDIHR 9 0 Q9Y5A9;A0A024R7W5;A0A087X0Q1;A0A087WY31;Q9Y5A9-2;Q9BYJ9;Q7Z739 Q9Y5A9 YTHDF2;YTHDF3;YTHDF1 YTH domain-containing family protein 2;YTH domain-containing family protein 1;YTH domain-containing family protein 3 0 0 ;;; ;;; 185.81 8.31E-05 51214500 13913.4 12164.6 12818.9 12509.9 13443.9 16349 12698 11388.4 15104.6 12683.6 FALSE FALSE TRUE 12812.13971 13216.05382 13293.97971 12458.13735 13283.59027 12958.03311 13054.27171 14860.67073 13447.66317 13124.35416 0.976211062 1.006986985 1.012924488 0.949238126 1.012132873 0.987327297 0.994660122 1.132297297 1.02463428 1 13.67995881 -4.261407173 5.795658155 0.990352836 1.136633625 0.7878566 0.021043857 0.036708375 5.387131012 0.002411659 0.021099703 5.48E-05 4.261407173 0.146280789 SYSLS(ph)ELSVLQAK ddPTM_HeLa_Curcumin_4h_R1 1 SYSLSELSVLQAK 13 0 Q9P0V3-2;Q9P0V3 Q9P0V3-2 SH3BP4 SH3 domain-binding protein 4 1 0 S(0.001)YS(0.124)LS(0.876)ELSVLQAK 143.55 0.00083722 233920000 4469.5 3196.3 3596 3871.1 3379.8 5587.3 3372.9 4094.4 5070.2 3079.8 TRUE FALSE FALSE 4115.734359 3472.57393 3729.270923 3855.082414 3339.498092 4428.430998 3467.534496 5342.763712 4514.011745 3186.822821 1.291485153 1.089666456 1.170215959 1.209694618 1.047908302 1.389606905 1.088085122 1.676517338 1.416461472 1 11.6379031 -1 0.026163816 2.21E-12 2.922275533 0.009551447 0.197203696 1646.594222 3.344797164 126.959932 272.8163358 0.1 1 2.922275533 SYSPYDMLESIRK ddPTM_HeLa_Curcumin_4h_R1 1 SYSPYDMLESIRK 13 1 P07355;H0YN42;A6NMY6;H0YM50;H0YN28;H0YL33;P07355-2 P07355;P07355-2 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 0 99.732 0.010519 22706000 1293.2 1533.8 1140.3 1368.5 963.96 2363.4 1902.1 1908.6 1927.1 1673.7 FALSE FALSE TRUE 1190.841855 1666.374838 1182.560521 1362.83751 952.4654066 1873.204199 1955.467807 2490.523354 1715.701951 1731.86095 0.687608237 0.96218743 0.682826483 0.786920861 0.549966443 1.081613509 1.129113631 1.438061961 0.990669575 1 10.75810739 -4.655893673 1.792615687 0.823954669 1.422637638 0.625260606 0.151824753 0.243541144 1.285420345 0.023544984 0.189925557 2.21E-05 4.655893673 0.598682969 SYSS(ph)PDITQAIQEEEK ddPTM_HeLa_Curcumin_4h_R1 1 SYSSPDITQAIQEEEK 16 0 P40818;P40818-2 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 0 S(0.132)YS(0.222)S(0.646)PDITQAIQEEEK 223.68 5.85E-16 39906000 2905 2380.5 2704.4 2713.5 2729.5 3181.1 2259.2 2438.9 3194.2 2727.9 TRUE FALSE FALSE 2675.066185 2586.259813 2804.627443 2702.272256 2696.952495 2521.304002 2322.587072 3182.509383 2843.804251 2822.694322 0.947699566 0.916238004 0.993599421 0.957337901 0.955453261 0.893226015 0.822826281 1.127472202 1.007478645 1 11.46285719 -9.144186968 0.616021216 1.006202994 0.945114168 0.06670737 0.073798031 2.304318454 1.364796864 0.077217412 0.01584829 7.17E-10 9.144186968 -0.061088826 SYSSGGEDGYVR ddPTM_HeLa_Curcumin_4h_R1 1 SYSSGGEDGYVR 12 0 Q13347 Q13347 EIF3I Eukaryotic translation initiation factor 3 subunit I 0 0 157.97 0.0023428 14338000 1972.7 1714 1604.5 1925.5 2021.9 2180.7 1733.5 1719.7 2427.7 1765.8 FALSE FALSE TRUE 1816.558713 1862.150523 1663.964181 1917.532791 1997.790163 1728.398238 1782.137345 2244.028613 2161.387384 1827.161419 0.994197171 1.019149432 0.910682638 1.049459983 1.093384603 0.945947206 0.975358458 1.228150174 1.182920875 1 10.83538838 -4.257952886 24.91101534 0.998268664 1.228150265 0.383101735 0.075599828 136.6937095 976631.3631 0.006263477 0.060589505 5.52E-05 4.257952886 0.229881601 DPQRS(ph)PLLEVK ddPTM_HeLa_Curcumin_4h_R1 1 DPQRSPLLEVK 11 1 A0A140T9E6;A2AB20;Q9BW19 A0A140T9E6 KIFC1 Kinesin-like protein KIFC1 1 0 DPQRS(1)PLLEVK 137.14 0.016972 11368000 3765.9 2802.8 2920.7 2872.4 3341.3 3768.4 2547.6 994.35 3940 2985.1 TRUE FALSE FALSE 3467.825041 3045.061543 3028.943711 2860.51477 3301.45718 2986.791361 2619.078799 1297.522738 3507.791857 3088.832003 1.122697848 0.985829446 0.980611347 0.926082988 1.068836757 0.966964652 0.847918824 0.420069054 1.135636983 1 11.59284569 -4.11411053 1.392414554 1.038782147 1.69E-13 0.895909602 0.062479625 0.408266739 0.537880261 0.009844587 0.650702242 7.69E-05 4.11411053 -1.038782147 down SYSSSSS(ph)SPER ddPTM_HeLa_Curcumin_4h_R1 1 SYSSSSSSPER 11 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 SYS(0.003)S(0.019)S(0.013)S(0.044)S(0.461)S(0.461)PER 103.08 0.0092646 30431000 4147.1 3579.4 3349.1 3628.7 3480.3 3912.5 2259.3 1557.9 3731.5 3052.5 TRUE FALSE FALSE 3818.852659 3888.787387 3473.220592 3613.685401 3438.799696 3101.003397 2322.689877 2032.896538 3322.163786 3158.574148 1.20904322 1.231184454 1.099616609 1.144087563 1.088719003 0.981773184 0.735360251 0.643612099 1.051792242 1 11.62505772 -4.797638212 1.823948651 1.114984323 0.631774919 0.876150155 0.064155563 0.132648815 0.794042287 0.012886235 0.076718523 1.59E-05 4.797638212 -0.483209404 SYSSSSSS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 3 SYSSSSSSPER 11 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 SYSSSSSS(1)PER;SYSSSSS(0.001)S(0.999)PER;SYSS(0.005)S(0.011)S(0.071)S(0.071)S(0.843)PER ;; 215.04 6.32E-11 94821000 14113.4 11458.6 12866.2 13076.2 13241.3 14135.4 9744.8 6822.7 13770.9 11418.9 TRUE FALSE FALSE 12996.3095 12449.03033 13343.03269 13022.09415 13083.40615 11203.5587 10018.21286 8902.909822 12260.26672 11815.70593 1.099918158 1.053600217 1.129262422 1.102100393 1.107289419 0.948192074 0.847872563 0.753480992 1.037624565 1 13.5284182 -4.809770017 2.017267219 1.062503365 0.767326833 0.879438308 0.040919757 0.110128063 0.837247824 0.007520019 0.039979819 1.55E-05 4.809770017 -0.295176531 SYSVGASGSS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 2 SYSVGASGSSSR 12 0 Q8N684-2;Q8N684;Q8N684-3;F5H669 Q8N684-2 CPSF7 Cleavage and polyadenylation specificity factor subunit 7 1 0 SYSVGASGS(0.087)S(0.911)S(0.002)R;SYSVGASGSS(0.998)S(0.002)R ; 158.34 0.00026545 60862000 4158.2 3091.6 3312.2 4179 3832.3 7656.2 21966.1 10700.2 4664.8 3229.75 TRUE FALSE FALSE 3829.074082 3358.824128 3434.953046 4161.708405 3786.602325 6068.217817 22582.40965 13962.64172 4153.083111 3341.983572 1.145748924 1.00503909 1.027818651 1.245280928 1.133040377 1.815753335 6.757187509 4.177950436 1.242700038 1 11.70648893 -4.859256238 5.595840343 1.095776901 5.437139474 0.89186866 0.596789343 0.034486617 1.606616645 0.07075301 0.221185768 1.38E-05 4.859256238 4.341362572 SYT(ph)RFGHGNQVS(ph)S(ph)LLS(ph)VR ddPTM_HeLa_Curcumin_4h_R1 1 SYTRFGHGNQVSSLLSVR 18 1 A0A087WZU1;A0A087X0B9;Q9UMZ3 A0A087WZU1 PTPRQ Protein-tyrosine-phosphatase;Phosphatidylinositol phosphatase PTPRQ 4 0 S(0.395)Y(0.062)T(0.544)RFGHGNQVS(1)S(1)LLS(1)VR 56.335 0.015717 4427200 1718.5 2429.5 1186 2708.5 1586.4 311.55 597.86 512.2 2363.1 1699.7 TRUE FALSE FALSE 1582.478912 2639.495154 1229.954203 2697.292945 1567.483216 246.9310181 614.6343425 668.3674221 2103.873842 1758.764448 0.899767398 1.500766721 0.699328557 1.533629445 0.891241131 0.140400278 0.349469392 0.380020999 1.196222635 1 10.78034656 -5.346349884 5.370814277 1.018830301 0.298047444 0.662782481 0.261910771 0.10160962 4.861578577 0.034665652 0.079156783 4.50E-06 5.346349884 -0.720782857 SYVDPSTDER ddPTM_HeLa_Curcumin_4h_R1 1 SYVDPSTDER 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 119.21 0.0030619 3963200 883.9 771 759.73 804.19 739.06 822.59 757.01 583.58 911.62 687.59 FALSE FALSE TRUE 813.9383823 837.6418045 787.8862621 800.8624749 730.2471922 651.9755615 778.2496632 761.5108555 811.6175668 711.4837013 1.144001445 1.177316926 1.107384836 1.125623079 1.026372341 0.916360502 1.093840466 1.070313844 1.140739507 1 9.474686898 -5.685057286 10.03796751 1.085561868 1.023417543 0.239603287 0.065502934 0.644280838 79.93115759 0.011508548 0.023025518 2.07E-06 5.685057286 -0.062144325 SYVS(ph)EPELATLSGDMAQPSLGLVGPESR ddPTM_HeLa_Curcumin_4h_R1 1 SYVSEPELATLSGDMAQPSLGLVGPESR 28 0 A0A1B0GUM1;A0A1B0GUN0;H0YDE2;A0A1B0GTN9;E9PKC0;Q6IQ23-3;Q6IQ23;Q6IQ23-2 A0A1B0GUM1 PLEKHA7 Pleckstrin homology domain-containing family A member 7 1 0 S(0.036)YVS(0.961)EPELAT(0.002)LSGDMAQPSLGLVGPESR 75.388 6.56E-05 1808400 1188.1 897.4 798.13 745.96 845.47 939.39 838.77 354.3 1071.2 967.46 TRUE FALSE FALSE 1094.060631 974.9672573 827.7093999 742.8734152 835.3883224 744.5499249 862.3036288 462.324439 953.69204 1001.079163 1.092881234 0.973916243 0.826817129 0.742072598 0.834487774 0.7437473 0.861374066 0.461826053 0.95266396 1 9.967340348 -6.717776305 2.131805205 1.044155523 0.742287739 0.593323006 0.107071195 0.136645368 1.272809268 0.016430206 0.023825509 1.92E-07 6.717776305 -0.301867784 SYVTTSTR ddPTM_HeLa_Curcumin_4h_R1 2 SYVTTSTR 8 0 P08670;B0YJC4;A0A1B0GTT5;A0A1B0GVG8 P08670 VIM Vimentin 0 0 ; ; 118.74 0.0028618 35975000 5330.2 2486.3 3825.6 3293.7 4352.3 5847.7 5536.9 4735.6 3625.4 3782.9 FALSE FALSE TRUE 4908.309046 2701.204693 3967.380101 3280.071542 4300.401665 4634.821103 5692.250512 6179.46264 3227.70269 3914.355493 1.253925213 0.690076488 1.013546191 0.837959543 1.098623176 1.184057276 1.45419866 1.578666692 0.824580878 1 11.93455907 -4.764521913 2.019926306 1.058569466 1.57925297 0.602150143 0.168655149 0.219903625 1.650619675 0.025381276 0.145526121 1.72E-05 4.764521913 0.520683504 T(ph)ADGRVSPAGGTLDDKPK ddPTM_HeLa_Curcumin_4h_R1 1 TADGRVSPAGGTLDDKPK 18 2 C9JA69;Q8WY36-2;Q8WY36 C9JA69 BBX HMG box transcription factor BBX 1 0 T(0.974)ADGRVS(0.026)PAGGTLDDKPK 79.341 0.013977 37320000 3336.3 3079.7 3325.4 3227.6 3516 2697.7 2531.8 1090 3216.6 2987.3 TRUE FALSE FALSE 3072.228335 3345.895545 3448.642249 3214.245046 3474.073996 2138.166611 2602.835494 1422.335982 2863.747028 3091.108453 0.99389212 1.082425802 1.115665239 1.03983574 1.123892626 0.691715171 0.842039525 0.460137845 0.926446636 1 11.59390856 -5.249570831 24.46094153 1.023335444 0.682371655 0.730648455 0.104004022 220.5714982 454593.8261 0.013397626 0.033839965 5.63E-06 5.249570831 -0.340963789 T(ph)AKDSDDDDDVAVTVDR ddPTM_HeLa_Curcumin_4h_R1 1 TAKDSDDDDDVAVTVDR 17 1 A0A0C4DFZ1;A8MZ54;Q16623-3;Q16623-2;Q16623 A0A0C4DFZ1 STX1A Syntaxin-1A 1 0 T(0.992)AKDS(0.008)DDDDDVAVTVDR 145.99 0.002634 7224800 1114.7 817.27 1055 1008.6 1220.8 1306.6 1053.9 1303.3 1257.7 980.65 TRUE FALSE FALSE 1026.470319 887.9111771 1094.099228 1004.42668 1206.242757 1035.596432 1083.469598 1700.67017 1119.733457 1014.727515 1.011572372 0.875024245 1.078219731 0.98984867 1.188735636 1.020566031 1.067744377 1.675987047 1.103481911 1 9.986876656 -4.257292159 3.942998593 1.014780015 1.7402527 0.853741149 0.079121811 0.058110636 1.82276583 0.009856054 0.121165689 5.53E-05 4.257292159 0.725472686 NSDDAPWS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 NSDDAPWSPK 10 0 H0Y589;H0Y3N9;Q9UPP1-5;Q9UPP1-4;Q9UPP1-3;Q9UPP1-2;Q9UPP1 H0Y589 PHF8 Histone lysine demethylase PHF8 1 0 NSDDAPWS(1)PK;NSDDAPWS(1)PK ; 124.81 0.0037332 93618000 17528 13547 16423.5 17361.9 15677.4 17107.1 13897.5 4542 17607.8 15339.2 TRUE FALSE FALSE 16140.6403 14717.94232 17032.16936 17290.06106 15490.45724 13558.89462 14287.42645 5926.834891 15676.26839 15872.23606 1.016910298 0.927275921 1.073079388 1.089327363 0.975946753 0.854252329 0.900152089 0.373408943 0.98765343 1 13.95421777 -4.113728712 1.490132733 1.006714685 4.06E-19 0.895141448 0.063051976 0.3509344 0.538239 0.008729708 0.574843469 7.70E-05 4.113728712 -1.006714685 down T(ph)AS(ph)PPPPPK ddPTM_HeLa_Curcumin_4h_R1 1 TASPPPPPK 9 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 0 T(1)AS(1)PPPPPK 129.88 0.01773 280050000 15177 12646 12687 14121 13741 14633 10877 6759.8 14564 12527 TRUE FALSE FALSE 13975.72444 13739.06389 13157.19138 14062.57104 13577.14755 11597.95085 11182.17935 8820.831902 12966.36564 12962.31232 1.07818143 1.059923843 1.015034282 1.084881362 1.047432527 0.894743975 0.862668563 0.680498331 1.0003127 1 13.66203548 -4.498760956 1.111090315 1.042698588 0.600685855 0.903662095 0.037216086 0.264870019 0.343433831 0.006189393 0.12319206 3.17E-05 4.498760956 -0.442012733 T(ph)AS(ph)PPPPPKR ddPTM_HeLa_Curcumin_4h_R1 2 TASPPPPPKR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 2 0 T(1)AS(1)PPPPPKR;T(1)AS(1)PPPPPKR ; 105.25 0.0072233 373860000 22654.8 18237 18966.5 20375.8 19724.3 23477.2 16892.5 10796.8 23152.1 20601.2 TRUE FALSE FALSE 20861.64867 19813.32502 19669.41517 20291.49034 19489.1006 18607.76408 17366.45809 14088.69462 20612.37255 21317.09017 0.978634913 0.929457298 0.922706384 0.951888376 0.914247698 0.872903569 0.814673014 0.660910777 0.966941191 1 14.3797229 -3.218602874 0.461564925 0.987765382 2.28E-17 0.941119793 0.023033656 1.648347123 0.116299399 0.005172055 1.102719941 0.000604501 3.218602874 -0.987765382 VT(ph)SLRSPGASVSSSLTSLCSSSSDPAPSDR ddPTM_HeLa_Curcumin_4h_R1 1 VTSLRSPGASVSSSLTSLCSSSSDPAPSDR 30 1 Q9P206;Q9P206-3;Q9P206-2 Q9P206 KIAA1522 Uncharacterized protein KIAA1522 1 0 VT(0.394)S(0.356)LRS(0.239)PGAS(0.005)VS(0.003)S(0.001)SLTSLCSSSSDPAPSDR 54.748 0.0026045 26056000 471.03 439.18 505.05 593.93 475.17 465.46 393.01 158.37 547.09 556.05 TRUE FALSE FALSE 433.7474785 477.1407623 523.7675973 591.472475 469.5039081 368.9183492 404.0368029 206.656284 487.0755958 575.3726961 0.753854817 0.829272514 0.910310136 1.027981479 0.815999632 0.641181536 0.702217546 0.359169431 0.846539294 1 9.16835295 -4.113377044 0.832192687 0.887779087 4.20E-16 0.748836772 0.092053044 1.349232893 0.57731872 0.018448274 1.162236255 7.70E-05 4.113377044 -0.887779087 down T(ph)ASELLLDRR ddPTM_HeLa_Curcumin_4h_R1 2 TASELLLDRR 10 1 Q92508 Q92508 PIEZO1 Piezo-type mechanosensitive ion channel component 1 1 0 T(0.987)AS(0.013)ELLLDRR;T(0.836)AS(0.164)ELLLDRR ; 107.09 0.0046373 7648300 3433.6 3000.4 2992.6 5197.7 3313.5 5197.5 2173.77 962.67 5924.4 4280.3 TRUE FALSE FALSE 3161.826937 3259.741206 3103.508389 5176.193295 3273.988677 4119.479912 2234.760136 1256.183651 5274.508142 4429.040106 0.71388537 0.735992705 0.700718059 1.168694157 0.739209535 0.930106708 0.504569858 0.283624357 1.190891935 1 12.11277835 -4.593518752 3.409596127 0.857526444 0.313113684 0.569017539 0.176710317 0.118100528 2.62859851 0.021939971 0.109995497 2.55E-05 4.593518752 -0.544412759 T(ph)ASGSS(ph)VTSLDGTR ddPTM_HeLa_Curcumin_4h_R1 1 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 2 0 T(0.575)AS(0.377)GS(0.408)S(0.592)VT(0.043)S(0.005)LDGTR 118.71 0.0085412 40768000 7037.6 6097.8 6161.9 5656.9 6527.1 6081.2 4860.6 5548.4 7439.1 5024.8 TRUE FALSE FALSE 6480.566534 6624.866661 6390.265435 5633.493247 6449.268595 4819.890571 4996.975354 7240.081618 6623.049342 5199.411426 1.246403872 1.274157038 1.22903631 1.083486723 1.240384356 0.927006958 0.961065579 1.392480999 1.273807514 1 12.3441326 -4.236222265 23.68432556 1.12224587 1.392481692 0.252696574 0.12937067 4229.997024 3972757.463 0.0191418 1.64640959 5.80E-05 4.236222265 0.270235822 QFSTAS(ph)DHEQPGVSG ddPTM_HeLa_Curcumin_4h_R1 1 QFSTASDHEQPGVSG 15 0 Q66K14;Q66K14-2;G3V133 Q66K14 TBC1D9B TBC1 domain family member 9B 1 0 QFS(0.194)T(0.114)AS(0.691)DHEQPGVS(0.002)G 80.488 0.01543 13473000 1587.5 1593.4 1380.7 1403.2 1794.4 3285.2 3018.7 6197.8 1702.2 1410.5 TRUE FALSE FALSE 1461.8477 1731.126396 1431.869957 1397.39393 1773.002952 2603.812488 3103.396598 8087.480689 1515.472919 1459.51477 1.001598428 1.18609721 0.981058901 0.957437334 1.214789318 1.784026131 2.126320789 5.541211953 1.038340241 1 10.5112731 -2.2360753 0.92472282 1.012471213 200 0.985657607 0.160335955 5.598603345 0.13573069 0.023437405 2217.200057 0.005806637 2.2360753 198.9875288 up T(ph)ASLNQRPR ddPTM_HeLa_Curcumin_4h_R1 1 TASLNQRPR 9 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 0 T(0.97)AS(0.03)LNQRPR 118.23 0.0054798 17662000 2683.9 1958.7 2448.4 2878.5 2429 4115 4689.9 3314.9 2023 2346.2 TRUE FALSE FALSE 2471.466483 2128.0013 2539.139858 2866.58953 2400.035761 3261.502614 4821.485972 4325.59775 1801.081961 2427.730275 1.018015266 0.876539425 1.045890428 1.180769363 0.988592426 1.343436974 1.98600562 1.781745606 0.741878939 1 11.24539243 -4.94503455 3.083864215 1.014636356 1.887476776 0.891955042 0.124434497 0.038645782 0.74113913 0.012317918 0.042694627 1.13E-05 4.94503455 0.872840419 T(ph)ASLPGYGR ddPTM_HeLa_Curcumin_4h_R1 1 TASLPGYGR 9 0 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 T(0.852)AS(0.148)LPGYGR 136.52 0.0083927 222920000 3028.7 1898.6 2793.9 2631 2626.7 2937.6 2188.3 1631.3 2775.8 3030.6 TRUE FALSE FALSE 2788.975199 2062.706524 2897.444392 2620.113619 2595.378318 2328.308646 2249.697808 2128.67586 2471.301685 3135.913124 0.889366219 0.657769027 0.923955568 0.83551856 0.82763081 0.742465927 0.717398002 0.67880575 0.788064461 1 11.61466988 -3.307852053 0.066115447 1.33409412 3.26E-15 0.129554253 0.097939443 69.65114869 0.56269795 3.028519589 10.16287044 0.000492207 3.307852053 -1.33409412 GVVIPT(ph)WNISPIKK ddPTM_HeLa_Curcumin_4h_R1 1 GVVIPTWNISPIKK 14 1 A0A087WUE6;Q3T8J9-2;Q3T8J9-3;Q3T8J9;A4PB68 A0A087WUE6 GON4L GON-4-like protein 1 0 GVVIPT(0.687)WNIS(0.313)PIKK 77.562 0.011411 34063000 3203.5 2583.4 2838 2928.8 2792.1 3577 2817.2 876.15 3717.8 3382.8 TRUE FALSE FALSE 2949.939595 2806.697585 2943.178777 2916.681402 2758.806031 2835.089879 2896.24305 1143.284102 3309.966641 3500.352048 0.842755116 0.801832943 0.840823647 0.83325373 0.788151018 0.809944211 0.827414789 0.326619747 0.94560964 1 11.77328431 -4.113111297 1.973196824 0.888191125 1.41E-31 0.836033274 0.06905878 0.454948627 1.329682949 0.012978773 0.832280603 7.71E-05 4.113111297 -0.888191125 down T(ph)ASPPPPPKR ddPTM_HeLa_Curcumin_4h_R1 1 TASPPPPPKR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 T(0.609)AS(0.391)PPPPPKR 105.36 0.0050279 408730000 10426 8995.6 8415.2 10232 10332 12618 11675 16489 12097 10782 TRUE FALSE FALSE 9600.771099 9773.13958 8727.074715 10189.6627 10208.79765 10000.88457 12002.56908 21516.42019 10769.98937 11156.6737 0.860540638 0.875990447 0.78222909 0.913324434 0.915039547 0.896403788 1.075819676 1.928569462 0.965340536 1 13.44561934 -4.251538885 2.849767602 0.913340698 2.12427349 0.966675686 0.056923771 0.066410193 0.731115185 0.009971921 0.187541989 5.60E-05 4.251538885 1.210932792 T(ph)AT(ph)LRHDADGQATSPGR ddPTM_HeLa_Curcumin_4h_R1 1 TATLRHDADGQATSPGR 17 1 H0YGV8 H0YGV8 PSMD3 2 0 T(1)AT(1)LRHDADGQATSPGR 82.505 0.0072588 43531000 1705.6 1279.8 1230.2 1335.7 1437.8 214.05 552.59 704.55 1420.4 1506.9 TRUE FALSE FALSE 1570.59996 1390.420209 1275.792294 1330.173227 1420.655174 169.6536172 568.0941882 919.3640517 1264.585674 1559.264663 1.007269643 0.891715334 0.818201249 0.853077261 0.911105862 0.108803605 0.364334678 0.589613857 0.81101413 1 10.60665011 -5.339911699 6.733859104 0.965224575 0.356808004 0.763153608 0.135676797 0.072140574 5.215840017 0.018888719 0.042593519 4.57E-06 5.339911699 -0.608416571 T(ph)AT(ph)PT(ph)VLS(ph)S(ph)SHSHR ddPTM_HeLa_Curcumin_4h_R1 1 TATPTVLSSSHSHR 14 0 A0A087WV20;A0A087WTU9;Q8TCU4-3;Q8TCU4-2;Q8TCU4 A0A087WV20 ALMS1 Alstrom syndrome protein 1 5 0 T(0.992)AT(0.977)PT(0.904)VLS(0.682)S(0.682)S(0.594)HS(0.169)HR 46.797 0.0096749 0 255.75 210.99 222.27 117.67 103.22 140.8 0 0 209.08 118.69 TRUE FALSE FALSE 235.5071176 229.2270354 230.5075217 117.1831127 101.9891689 111.5964929 0 0 186.1444471 122.8144687 1.917584469 1.866449759 1.876875943 0.954147455 0.830432847 0.908659168 0 0 1.515655681 1 6.940336723 -5.23553946 1.063923301 1.498214615 4.76E-08 0.757692418 0.333533582 0.325297863 0.619251322 0.070398845 0.369639669 5.81E-06 5.23553946 -1.498214567 T(ph)AVPSPVEAAAASDPAAAR ddPTM_HeLa_Curcumin_4h_R1 1 TAVPSPVEAAAASDPAAAR 19 0 Q147X3;J3KNC2;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 0 T(0.999)AVPS(0.001)PVEAAAASDPAAAR 173.34 8.21E-06 19909000 3667 3624.6 3818.3 3082.2 3028.1 3583 2700.4 2193.9 3450 3781.7 TRUE FALSE FALSE 3376.753081 3937.894273 3959.809557 3069.446673 2991.991885 2839.845411 2776.165956 2862.810011 3071.543631 3913.113794 0.862932503 1.006332675 1.011933147 0.784400055 0.764606409 0.725725231 0.709451885 0.731593856 0.784935934 1 11.93410135 -6.105947544 4.296352905 0.945062592 0.734562522 0.666401715 0.06759947 0.090327336 2.824829334 0.009310024 0.015872324 7.84E-07 6.105947544 -0.21050007 T(ph)DDT(ph)SGEDNDEKEAVASK ddPTM_HeLa_Curcumin_4h_R1 1 TDDTSGEDNDEKEAVASK 18 1 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;C9JQE8 Q9Y618 NCOR2 Nuclear receptor corepressor 2 2 0 T(0.884)DDT(0.844)S(0.272)GEDNDEKEAVASK 57.525 0.020435 28164000 3591.7 3292.5 3427.7 3372.4 3860.8 3754.1 3560.6 2447.4 3528.3 3074 TRUE FALSE FALSE 3307.413155 3577.089029 3554.733577 3358.445902 3814.762482 2975.457343 3660.500853 3193.600994 3141.254317 3180.821271 1.03979849 1.124580328 1.117552127 1.05584238 1.19930111 0.935436822 1.150803689 1.004017743 0.987560774 1 11.63518359 -7.596693495 2.503903076 1.014771232 1.085272812 0.186816032 0.071594643 0.324180178 4.227608936 0.012236835 0.012862727 2.53E-08 7.596693495 0.07050158 YYS(ph)IDDNQNK ddPTM_HeLa_Curcumin_4h_R1 2 YYSIDDNQNK 10 0 Q8NI08-2;Q8NI08;Q8NI08-4;Q8NI08-3;Q5TF97;Q5TF96 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 0 YYS(1)IDDNQNK;YYS(1)IDDNQNK ; 163.45 0.00059501 56184000 3960.1 3233.7 4568 4702.9 4861.9 5116.1 6203.3 10969.9 3716.6 2813.7 TRUE FALSE FALSE 3646.653906 3513.206619 4737.294098 4683.440646 4803.925018 4054.96319 6377.347903 14314.57201 3308.898278 2911.475866 1.252510436 1.206675508 1.627110894 1.608613934 1.64999651 1.392751778 2.190417574 4.916603356 1.136502046 1 11.50753494 -2.178049847 0.943179744 1.208801373 200 0.954204437 0.23297882 14.82903898 0.309206424 0.042291385 6043.833731 0.006636669 2.178049847 198.7911986 up T(ph)DLQGSASPSK ddPTM_HeLa_Curcumin_4h_R1 1 TDLQGSASPSK 11 0 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 0 T(0.957)DLQGSAS(0.038)PS(0.005)K 144.17 0.0031021 6245400 2906.7 2518.2 3254.9 2549.9 3428.6 2789.1 2164.3 1387.7 2518.2 2317 TRUE FALSE FALSE 2676.631628 2735.861987 3375.529457 2539.349189 3387.716184 2210.60922 2225.024433 1810.803342 2241.95976 2397.515578 1.116418868 1.141123759 1.407928061 1.059158578 1.413011125 0.922041651 0.928054213 0.755283244 0.935117912 1 11.22732447 -5.020832781 24.29949175 1.113008661 0.862513391 0.402723065 0.155206582 434.0143806 506239.2504 0.021746505 0.05619164 9.53E-06 5.020832781 -0.25049527 GLPPS(ph)MER ddPTM_HeLa_Curcumin_4h_R1 7 GLPPSMER 8 0 P38159;P38159-2;H3BUY5 P38159 RBMX "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed" 1 0 GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER;GLPPS(1)MER ;;;;;; 154.01 0.0015269 1496458000 44460.6 40820.7 39826.6 43706.5 41281 46974 39360.8 11882.77 47638.9 43734.7 TRUE FALSE FALSE 40941.4966 44349.05941 41302.60883 43525.65408 40788.75104 37231.06289 40465.15811 15505.77187 42413.03186 45254.47757 0.904694934 0.979992739 0.912674525 0.961797736 0.901319675 0.822704512 0.894169158 0.342635087 0.937211833 1 15.46577292 -4.112999074 2.02802204 0.943709377 9.24E-19 0.92186823 0.050522916 0.257238263 0.801378962 0.007980405 0.511321357 7.71E-05 4.112999074 -0.943709377 down T(ph)DSQTIGDFATR ddPTM_HeLa_Curcumin_4h_R1 1 TDSQTIGDFATR 12 0 Q13480-2 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 0 T(0.751)DS(0.232)QT(0.017)IGDFATR 134.04 0.005655 19644000 1499.5 903.64 1210.9 1174.6 1221.6 1248 1424.4 821.48 1231.3 981.87 TRUE FALSE FALSE 1380.812993 981.7466151 1255.777019 1169.739816 1207.033218 989.1507321 1464.36483 1071.94547 1096.229471 1015.989909 1.359081404 0.966295635 1.236013279 1.151330152 1.18803662 0.973583225 1.441318282 1.055074918 1.07897673 1 9.988670358 -9.695925209 1.582782714 1.000158225 1.200349337 0.080769171 0.148097598 0.496748494 2.246444548 0.102521996 0.022752851 2.01E-10 9.695925209 0.200191112 T(ph)DSVIIADQTPTPTR ddPTM_HeLa_Curcumin_4h_R1 1 TDSVIIADQTPTPTR 15 0 K7ELQ4;P17544-4;P17544-2;P17544;P17544-3;P17544-1;K7ESA4;P17544-5 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 0 T(0.933)DS(0.067)VIIADQTPTPTR 164.66 0.0007227 9814100 1571 1139 1414.7 1834.2 1617.7 1323.6 1537.9 1461.3 1122.7 1172.5 TRUE FALSE FALSE 1446.653692 1237.450085 1467.130026 1826.610566 1598.409984 1049.07044 1581.049335 1906.843643 999.5426189 1213.244288 1.192384507 1.019951297 1.209261846 1.505558761 1.317467554 0.864681953 1.303158276 1.571689776 0.823859324 1 10.24465435 -1.000000044 0.030064949 6.64E-11 2.979226318 0.352847452 0.193531097 1300.726044 3.029490311 96.29793301 231.7122586 0.09999999 1.000000044 2.979226318 T(ph)DTGIVTVEQSPSSSK ddPTM_HeLa_Curcumin_4h_R1 1 TDTGIVTVEQSPSSSK 16 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 T(0.789)DT(0.001)GIVTVEQS(0.208)PS(0.002)SSK 276.75 8.91E-65 40769000 6159.1 5170.8 5176.1 5765 5539.2 8258.4 6631.4 3882.7 5799.2 5022.2 TRUE FALSE FALSE 5671.600736 5617.740911 5367.930819 5741.145958 5473.148658 6545.514749 6817.459237 5066.517356 5163.042269 5196.721076 1.091380633 1.081016439 1.032945725 1.104763152 1.053192692 1.259547059 1.311877073 0.974945024 0.99351922 1 12.34338591 -6.572616611 0.218051797 0.983677451 1.220197808 0.237604931 0.093035335 3.800503715 0.519782389 0.164491121 0.315580505 2.68E-07 6.572616611 0.236520357 T(ph)DYNASVSVPDSSGPER ddPTM_HeLa_Curcumin_4h_R1 1 TDYNASVSVPDSSGPER 17 0 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 0 T(0.565)DYNAS(0.427)VS(0.008)VPDSSGPER 240.66 6.32E-30 11871000 3253.7 2734.6 2797.5 3076 2985.2 3772.1 2835.7 2740.1 3180.3 3020.5 TRUE FALSE FALSE 2996.166212 2970.966639 2901.177811 3063.272327 2949.60344 2989.72394 2915.26211 3575.543876 2831.429047 3125.46215 0.958631418 0.950568747 0.928239624 0.980102199 0.943733534 0.956570195 0.932745933 1.144004856 0.90592332 1 11.60985382 -4.254336508 24.98176149 0.968174342 1.144004938 0.77407061 0.030022202 290.5649157 1021930.622 0.003845829 0.051935509 5.57E-05 4.254336508 0.175830597 T(ph)EMDKSPFNSPSPQDSPR ddPTM_HeLa_Curcumin_4h_R1 2 TEMDKSPFNSPSPQDSPR 18 1 A0A286YEX4;P08651-4;P08651-5;P08651-3;P08651-6;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 0 T(0.988)EMDKS(0.012)PFNSPSPQDSPR;T(0.994)EMDKS(0.006)PFNSPSPQDSPR ; 196.67 3.06E-34 9895700 10714.3 9147.9 8739.2 10698.1 9247.5 11629.7 8723.6 6061.8 11705.1 10164.3 TRUE FALSE FALSE 9866.251849 9938.603714 9063.08244 10653.8341 9137.229602 9217.569126 8968.360738 7910.014915 10421.07981 10517.50867 0.938078794 0.944957977 0.861713807 1.01296176 0.868763686 0.876402332 0.852707711 0.752080665 0.990831588 1 13.36050539 -1.643053921 0.252559432 0.986320886 1.79E-15 0.704466876 0.04232876 13.91756195 0.232694524 0.022414471 5.545162938 0.02274815 1.643053921 -0.986320886 T(ph)ESPATAAETASEELDNR ddPTM_HeLa_Curcumin_4h_R1 2 TESPATAAETASEELDNR 18 0 C9JWF0;C9IYK2;C9JJ64;C9JR83;Q9NTJ3-2;Q9NTJ3 C9JWF0 SMC4 Structural maintenance of chromosomes protein 4 1 0 T(0.587)ES(0.29)PAT(0.123)AAETASEELDNR;T(0.464)ES(0.464)PAT(0.072)AAETASEELDNR ; 176.94 2.93E-06 308306000 15136.6 12039.3 14807.7 14492.5 14503.6 17394.6 14222.5 11538.1 18164.8 15575.1 TRUE FALSE FALSE 13938.52214 13079.92345 15356.48639 14432.53388 14330.65404 13786.76388 14621.54507 15056.01358 16172.16689 16116.33357 0.864869301 0.811594237 0.952852355 0.895522162 0.889200635 0.855452875 0.90725009 0.934208362 1.003464393 1 13.97623595 -9.28946477 1.008877854 1.000217037 0.887249072 0.581211262 0.038056406 0.323916795 0.589234356 0.026128178 0.00698491 5.13E-10 9.28946477 -0.112967965 T(ph)FDDS(ph)FKEKEILQIK ddPTM_HeLa_Curcumin_4h_R1 1 TFDDSFKEKEILQIK 15 2 G3V5X4;A0A0A0MRE3;Q8WXH0;Q8WXH0-2 G3V5X4 SYNE2 Nesprin-2 2 0 T(1)FDDS(1)FKEKEILQIK 79.466 0.0083762 0 1625 1354.7 1430.5 1597.8 1412.1 1661.1 1315.6 1032.6 1343.4 1213.1 TRUE FALSE FALSE 1496.379535 1471.794232 1483.515588 1591.188727 1395.26163 1316.569136 1352.512195 1347.434986 1196.032381 1255.255135 1.192091945 1.172506043 1.181843872 1.267621763 1.111536285 1.048845847 1.077479915 1.073435152 0.952820146 1 10.29376491 -2.781699548 12.80275578 1.11120774 0.666144032 0 0.091466817 0 0 0.012840592 0 0.001653105 2.781699548 -0.445063709 T(ph)FMKDSVVGSSK ddPTM_HeLa_Curcumin_4h_R1 1 TFMKDSVVGSSK 12 1 Q9H582;Q9H582-2;A0A087WZL9 Q9H582 ZNF644 Zinc finger protein 644 1 0 T(1)FMKDSVVGSSK 59.864 0.017741 81719000 13954 10784 10762 11916 11926 16916 13175 5591.5 13183 11010 TRUE FALSE FALSE 12849.52618 11716.12091 11160.84919 11866.69475 11783.79024 13407.43092 13544.65504 7296.32261 11736.85788 11392.59668 1.127883883 1.02839776 0.979658062 1.041614575 1.034337524 1.176854697 1.188899723 0.640444213 1.030217975 1 13.47580899 -4.25091068 24.74102528 1.065200992 0.640443934 0.776080966 0.068813527 521.0162757 1224290.723 0.010609457 0.202238073 5.61E-05 4.25091068 -0.424757057 T(ph)FS(ph)ICKERMRPVK ddPTM_HeLa_Curcumin_4h_R1 2 TFSICKERMRPVK 13 3 O14646-2;O14646;H0Y8V4;A0A087WVF4 O14646-2 CHD1 Chromodomain-helicase-DNA-binding protein 1 2 0 T(1)FS(1)ICKERMRPVK;T(1)FS(1)ICKERMRPVK ; 65.295 0.014868 36509000 3741.9 3248.8 3475 4426.5 3868 4320 3962.7 3030 3918.3 3669.8 TRUE FALSE FALSE 3445.724667 3529.611796 3603.786557 4408.184316 3821.876626 3423.983304 4073.882697 3953.833052 3488.472293 3797.325277 0.907408351 0.92949946 0.949032883 1.160865608 1.006465432 0.901682909 1.072829531 1.041215267 0.91866565 1 11.89076787 T(ph)FS(ph)LKS(ph)QLIVHQRS(ph)HT(ph)GVK ddPTM_HeLa_Curcumin_4h_R1 1 TFSLKSQLIVHQRSHTGVK 19 2 Q14587-2;Q14587 Q14587-2 ZNF268 Zinc finger protein 268 5 0 T(1)FS(1)LKS(1)QLIVHQRS(1)HT(1)GVK 53.255 0.012049 2403300 343.11 371.15 372.4 255.82 361.88 552.2 403.95 271.55 423.73 348.2 TRUE FALSE FALSE 315.9524815 403.2305522 386.2014716 254.7614846 357.5648174 437.6674954 415.2837498 354.3443449 377.2478791 360.2999241 0.876915204 1.119152476 1.071888851 0.707081705 0.992408806 1.214731023 1.15260571 0.983470496 1.047038464 1 8.493054538 -5.504502367 24.18458091 0.947387503 1.117680651 0.213476391 0.122092712 476.6728422 627333.0545 0.017135018 0.037636666 3.13E-06 5.504502367 0.170293149 T(ph)FSLTEVR ddPTM_HeLa_Curcumin_4h_R1 2 TFSLTEVR 8 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 0 T(0.972)FS(0.012)LT(0.016)EVR;T(0.989)FS(0.011)LTEVR ; 142.36 0.0080768 129966000 7303.7 5336.3 6932.4 6579.4 5932.1 6773.4 5517.3 8023 7427.8 6665.9 TRUE FALSE FALSE 6725.604438 5797.545994 7189.320842 6552.176186 5861.363582 5368.520488 5672.100589 10469.17577 6612.988923 6897.539529 0.975072982 0.840523779 1.042302231 0.949929487 0.849776005 0.77832399 0.822336801 1.517813087 0.958746071 1 12.7518661 -4.253663599 24.96968676 0.947695767 1.517813367 0.803143137 0.088339424 356.7237715 1145488.677 0.013635992 0.196693221 5.58E-05 4.253663599 0.5701176 T(ph)FSPTYGLLR ddPTM_HeLa_Curcumin_4h_R1 2 TFSPTYGLLR 10 0 O15061;H0YL34;A0A075B7B1;O15061-2 O15061 SYNM Synemin 1 0 T(0.925)FS(0.053)PT(0.021)YGLLR;T(0.888)FS(0.083)PT(0.029)YGLLR ; 128.51 0.009074 63960000 5781.3 3194.3 4598 4160.3 4503.5 4802.1 3552.7 1623.79 4716.8 4156.3 TRUE FALSE FALSE 5323.704005 3470.401058 4768.405925 4143.085781 4449.798704 3806.090329 3652.3792 2118.876096 4199.378841 4300.731116 1.237860229 0.806932813 1.108743094 0.963344527 1.034660988 0.884986814 0.849246117 0.492678114 0.97643371 1 12.07036622 -3.968926387 0.676846871 1.087611283 1.81E-16 0.615897579 0.117671345 1.949800709 0.474146841 0.021745617 1.780638125 0.000107417 3.968926387 -1.087611283 T(ph)GPPPISPSK ddPTM_HeLa_Curcumin_4h_R1 1 TGPPPISPSK 10 0 A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-2;Q14135;Q14135-4;A0A096LP98;E7EUJ2;F8WBN7;F8W708;E7ERW0;E7EQU6;E7EWF5 A0A075B6E4 VGLL4 Transcription cofactor vestigial-like protein 4 1 0 T(0.999)GPPPIS(0.001)PSK 124.08 0.01119 17492000 2136.5 1910.3 1648.5 2005.4 2149.7 1956.7 1630.1 1100.4 2042.6 1623.2 TRUE FALSE FALSE 1967.393771 2075.41782 1709.59486 1997.102186 2124.066232 1550.858363 1675.836219 1435.906894 1818.53189 1679.606079 1.171342373 1.235657483 1.017854651 1.189030101 1.264621662 0.923346481 0.997755509 0.85490694 1.08271333 1 10.7139072 -5.219550238 24.88738958 1.108619178 0.932578123 0.519055307 0.090525797 387.4162885 230173.1103 0.014696504 0.037468622 6.03E-06 5.219550238 -0.176041055 T(ph)GQARMSATPTPAGEGAR ddPTM_HeLa_Curcumin_4h_R1 1 TGQARMSATPTPAGEGAR 18 1 A0A0C4DFP5;P35398-1 A0A0C4DFP5 RORA 1 0 T(0.963)GQARMS(0.017)AT(0.017)PT(0.003)PAGEGAR 82.505 0.0083314 22876000 2143.6 1962.3 2035.1 1794.3 2247 3076.8 2258.6 1985.4 2364.4 2118 TRUE FALSE FALSE 1973.931798 2131.912468 2110.522596 1786.875662 2220.205993 2438.636997 2321.970237 2590.73932 2105.031235 2191.600342 0.900680548 0.972765165 0.963005232 0.815329158 1.013052403 1.112719756 1.059486163 1.182122155 0.960499592 1 11.09776902 -5.41507529 3.973859108 0.944922346 1.111358176 0.675058218 0.056194202 0.11974861 3.303850144 0.008713597 0.020229816 3.85E-06 5.41507529 0.16643583 T(ph)GSEPALSPAVVR ddPTM_HeLa_Curcumin_4h_R1 1 TGSEPALSPAVVR 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 0 T(0.809)GS(0.188)EPALS(0.003)PAVVR 145.81 0.0021384 16954000 1303.6 1258.9 1117.4 1412.7 1665.4 1897.3 1966.1 665.15 1306.6 1641.6 TRUE FALSE FALSE 1200.418684 1367.713706 1158.811827 1406.854622 1645.541193 1503.778593 2021.263475 867.951173 1163.269249 1698.645478 0.706691714 0.805179023 0.682197576 0.828221451 0.968737276 0.885281015 1.189926621 0.51096664 0.684821679 1 10.73016907 -4.202299865 22.57179921 0.866144918 0.510957069 0.323031149 0.151966531 25284.79301 9649260.979 0.021806532 56.01158517 6.28E-05 4.202299865 -0.35518785 ALHSFIT(ph)PPTTPQLR ddPTM_HeLa_Curcumin_4h_R1 2 ALHSFITPPTTPQLR 15 0 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;J3QR75 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 0 ALHSFIT(0.999)PPTTPQLR;ALHSFIT(1)PPTTPQLR ; 133.9 0.00061744 108307000 4077.3 3013.7 3304.1 3017 3507.5 3641.3 2884.4 956.96 3583.6 3412.4 TRUE FALSE FALSE 3754.577403 3274.190799 3426.552853 3004.516453 3465.675353 2886.053334 2965.328501 1248.732699 3190.488046 3530.980646 1.063324266 0.927275204 0.970425272 0.850901422 0.981505055 0.817351785 0.839803102 0.353650395 0.903569961 1 11.7858532 -4.112568128 0.917414387 1.006808737 8.30E-51 0.804737207 0.082888525 0.733418564 0.386273727 0.012116063 0.783119079 7.72E-05 4.112568128 -1.006808737 down T(ph)GSESS(ph)QTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 2 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 0 T(0.952)GS(0.048)ES(0.137)S(0.805)QT(0.057)GTSTTSSR;T(0.804)GS(0.196)ES(0.002)S(0.807)QT(0.06)GT(0.003)S(0.001)T(0.001)T(0.007)S(0.032)S(0.088)R ; 189.52 2.02E-06 164812100 11071.2 11532 12415.8 11682.2 12742.4 12936.3 9017.9 4893.4 11090.6 11519.2 TRUE FALSE FALSE 10194.90284 12528.77469 12875.94047 11633.86215 12590.4552 10253.16556 9270.918004 6385.375134 9873.988927 11919.49134 0.855313582 1.051116556 1.080242445 0.976036797 1.056291317 0.860201603 0.777794768 0.535708693 0.828390125 1 13.54103505 -4.398603634 1.550852876 0.960698942 0.446157836 0.735682857 0.081587544 0.347222236 0.941852935 0.012594922 0.249200107 3.99E-05 4.398603634 -0.514541106 T(ph)GSESSQTGTSTTS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 2 0 T(0.644)GS(0.356)ESS(0.024)QT(0.024)GT(0.002)S(0.003)T(0.036)T(0.159)S(0.615)S(0.136)R 114.21 0.0058961 924740 424.94 404.63 436.12 597.83 423.53 348.24 417.12 0 460.94 502.12 TRUE FALSE FALSE 391.3055506 439.6044142 452.2829909 595.3563379 418.4796814 276.0110985 428.8232646 0 410.3760352 519.5686326 0.75313544 0.846094985 0.870497106 1.145866591 0.80543677 0.531231258 0.825344791 0 0.789839897 1 9.021170525 -4.356125634 1.470502993 0.882872947 2.14E-50 0.659116671 0.171538914 0.496763784 1.105302547 0.025023063 0.604257283 4.40E-05 4.356125634 -0.882872947 T(ph)GSESSQTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 1 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 T(0.681)GS(0.318)ESSQTGTSTTSSR 150.37 0.0010096 3563500 166.27 209.25 185.24 139.28 178.16 149.31 149.77 0 0 203.3 TRUE FALSE FALSE 153.1095541 227.3366376 192.1051574 138.7036963 176.0355584 118.3414229 153.9721431 0 0 210.3646599 0.727829257 1.080678845 0.913200713 0.659348849 0.836811461 0.562553725 0.731929703 0 0 1 7.71674855 -4.440672669 1.029688708 0.874184029 1.51E-35 0.204142639 0.318876808 0.696438404 0.699052211 0.025229267 0.619932687 3.63E-05 4.440672669 -0.874184029 T(ph)GSGQGPSSTGQPGR ddPTM_HeLa_Curcumin_4h_R1 1 TGSGQGPSSTGQPGR 15 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 T(0.848)GS(0.109)GQGPS(0.014)S(0.026)T(0.002)GQPGR 110.93 0.0061794 11166000 643.72 551.44 559.81 543.09 584.72 950.6 1295.1 395.37 861.03 445.73 TRUE FALSE FALSE 592.7688827 599.1040164 580.5570511 540.8428375 577.7475959 753.4348445 1331.43702 515.9164929 766.5771632 461.2190843 1.285221932 1.29895756 1.258744642 1.172637594 1.252653274 1.633572569 2.886777815 1.118593117 1.662067311 1 8.8493084 -5.101475751 3.844087923 1.170467877 2.051093108 0.279323322 0.4376111 0.140926035 3.721161439 0.051740793 0.145173665 7.92E-06 5.101475751 0.88062523 T(ph)GSGSPFAGNSPAR ddPTM_HeLa_Curcumin_4h_R1 1 TGSGSPFAGNSPAR 14 0 M0QY97;Q9UPT8 M0QY97 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 0 T(0.893)GS(0.009)GS(0.097)PFAGNS(0.002)PAR 148.85 0.0015709 45084000 1923.1 1819.4 1429.3 1826 2079.6 2207.9 1573.5 883.11 1609 2218.4 TRUE FALSE FALSE 1770.884606 1976.660829 1482.271115 1818.444496 2054.802128 1749.956652 1617.648175 1152.366174 1432.496726 2295.489235 0.771462823 0.861106556 0.645732114 0.79218167 0.895147796 0.762345833 0.704707367 0.502013321 0.624048549 1 11.16458595 -13.52287875 0.071535968 1.905446774 0.413913445 0 0.145051784 124.619537 0.691298997 18.86513562 2.609023061 3.00E-14 13.52287875 -1.491533329 T(ph)GSNISGASSDISLDEQYK ddPTM_HeLa_Curcumin_4h_R1 1 TGSNISGASSDISLDEQYK 19 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 0 T(0.374)GS(0.374)NIS(0.157)GAS(0.082)S(0.012)DIS(0.001)LDEQYK 65.197 0.0091692 0 1005.6 773.21 925.27 1158.7 1112.4 914.18 524.87 605.7 869.83 900.69 TRUE FALSE FALSE 926.0056989 840.042827 959.5613202 1153.905606 1099.135357 724.5687631 539.5964396 790.3751417 774.4118252 931.9889105 0.993580169 0.90134423 1.029584483 1.238110876 1.179343814 0.777443546 0.578973026 0.848052088 0.830923862 1 9.864168978 -5.09495125 6.089260547 1.020677126 0.705067482 0.5265469 0.126728414 0.11686149 6.139988674 0.01624868 0.042353762 8.04E-06 5.09495125 -0.315609644 T(ph)GSPGPELLFHEGQQK ddPTM_HeLa_Curcumin_4h_R1 1 TGSPGPELLFHEGQQK 16 0 A6NHN7;A6NHB5;A6NL54;Q14202-2;Q14202;Q14202-3 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 0 T(0.518)GS(0.482)PGPELLFHEGQQK 101.28 0.0012161 0 1686.4 1762.9 1684.2 1757.9 1914.3 1712 1522.6 1189.4 2059.3 1826.6 TRUE FALSE FALSE 1552.919661 1915.277221 1746.617934 1750.626276 1891.473223 1356.911902 1565.320058 1552.042585 1833.399942 1890.074214 0.821618352 1.013334401 0.924100186 0.926220919 1.000740187 0.717914615 0.828179151 0.821154309 0.97001479 1 10.88422717 -5.261992137 24.99999795 0.927807171 0.792992338 0.570213106 0.06211894 39.00984432 1764385.226 0.010968117 0.026016172 5.47E-06 5.261992137 -0.134814833 T(ph)GSSGALGPPERR ddPTM_HeLa_Curcumin_4h_R1 2 TGSSGALGPPERR 13 1 Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4;K7EL81;Q9BZL4-3 Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 0 T(0.972)GS(0.014)S(0.014)GALGPPERR;T(0.716)GS(0.225)S(0.059)GALGPPERR ; 79.804 0.011669 12926000 2279.49 1996.62 1972.49 2293.38 1843.63 3105.2 2536.7 1355.75 2685.2 2466.75 TRUE FALSE FALSE 2099.065961 2169.198936 2045.592215 2283.890601 1821.645916 2461.146517 2607.872975 1769.111934 2390.640278 2552.469379 0.822366755 0.849843275 0.801416946 0.894776886 0.713679832 0.96422176 1.021705881 0.693098201 0.936599004 1 11.31767794 -9.291475035 0.939957476 1.003049254 0.849534768 0.193815279 0.097099717 0.639692084 0.981463733 0.06838726 0.01701005 5.11E-10 9.291475035 -0.153514486 T(ph)PAPEPEPCEASELPAKR ddPTM_HeLa_Curcumin_4h_R1 2 TPAPEPEPCEASELPAKR 18 1 H0Y5D5;A0A494C0L7;Q9BTG3;Q5SYW2;F5H2X7;Q9ULV3-5;Q9ULV3-3;Q9ULV3-4;Q9ULV3-2;Q9ULV3 H0Y5D5 CIZ1 Cip1-interacting zinc finger protein 1 0 T(1)PAPEPEPCEASELPAKR;T(1)PAPEPEPCEASELPAKR ; 118.84 0.00020574 26586000 3595.2 3213.6 3664.7 3481.2 3793.5 3347.1 2816.8 934.15 3601.3 2730.4 TRUE FALSE FALSE 3310.636126 3491.369264 3800.517006 3466.795717 3748.26499 2652.87373 2895.831827 1218.968035 3206.2464 2825.281197 1.171789955 1.23575992 1.345181857 1.227062184 1.326687409 0.938976883 1.024971189 0.431450164 1.134841517 1 11.46417875 -4.111454224 1.666325129 1.13529518 2.69E-17 0.758925604 0.124047025 0.67806591 1.334998302 0.020955067 1.379956175 7.74E-05 4.111454224 -1.13529518 down T(ph)IASDS(ph)EEEAGK ddPTM_HeLa_Curcumin_4h_R1 2 TIASDSEEEAGK 12 0 Q96ST2-3;Q96ST2;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 2 0 T(0.866)IAS(0.135)DS(1)EEEAGK;T(0.987)IAS(0.013)DS(1)EEEAGK ; 173.59 0.00053452 58131000 12678.2 11616.2 12651.3 11435.6 13776.7 13464 12968.2 10412.1 10265.8 9776.8 TRUE FALSE FALSE 11674.70709 12620.25257 13120.16831 11388.28252 13612.42185 10671.41463 13332.05279 13586.70136 9139.667424 10116.54307 1.154021389 1.247486664 1.296902332 1.125708894 1.345560608 1.054847941 1.317846689 1.343018189 0.903437801 1 13.30442877 -8.430038834 0.383464186 0.962282651 1.26699808 0.588220261 0.095042602 0.850160311 0.264413028 0.10750082 0.040033967 3.72E-09 8.430038834 0.304715429 T(ph)ISDGTISASK ddPTM_HeLa_Curcumin_4h_R1 1 TISDGTISASK 11 0 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 0 T(0.846)IS(0.133)DGT(0.021)ISASK 171.49 0.00067277 155540000 11813 9623.5 10615 10962 10978 13449 10528 7374.6 11019 8972.6 TRUE FALSE FALSE 10877.98858 10455.31246 11008.40124 10916.64215 10847.09452 10659.5258 10823.38735 9623.081592 9810.243268 9284.397182 1.171641882 1.126116457 1.185688314 1.175805164 1.168314357 1.148111783 1.165760914 1.03647888 1.056637612 1 13.18059253 -9.268492632 0.84458592 0.99332694 1.151515988 0.523787235 0.043983298 0.315788488 0.377283687 0.03300447 0.007628553 5.39E-10 9.268492632 0.158189048 T(ph)ISPAESTALLQGR ddPTM_HeLa_Curcumin_4h_R1 1 TISPAESTALLQGR 14 0 Q03188;H0Y8J2;Q03188-2 Q03188 CENPC Centromere protein C 1 0 T(0.998)IS(0.002)PAESTALLQGR 177.93 0.00047073 8271000 1453.9 983.86 870.78 1132.9 1186.7 1352.7 954.03 580.37 1121.6 1017.2 TRUE FALSE FALSE 1338.822281 1068.900474 903.0518728 1128.21236 1172.549378 1072.134772 980.7975142 757.3221413 998.5632861 1052.547624 1.271982616 1.015536447 0.857967708 1.071887232 1.114010759 1.018609274 0.931831959 0.71951342 0.948710788 1 10.0396698 -3.58482879 0.722893455 1.103193386 1.13E-14 0.34320017 0.114211194 4.720516642 0.872959792 0.022157296 5.34082813 0.000260118 3.58482879 -1.103193386 T(ph)ISVSGSTAK ddPTM_HeLa_Curcumin_4h_R1 1 TISVSGSTAK 10 0 Q8TDJ6;Q8TDJ6-3 Q8TDJ6 DMXL2 DmX-like protein 2 1 0 T(0.892)IS(0.107)VS(0.001)GS(0.001)TAK 119.27 0.013603 14175000 2238 1989.9 2500.1 2899.5 2397.7 3098.6 2518.7 4353.8 2218.1 3113.1 TRUE FALSE FALSE 2060.859938 2161.898089 2592.755905 2887.502637 2369.108993 2455.915432 2589.367943 5681.253578 1974.779979 3221.279993 0.6397643 0.671130139 0.804883745 0.896383625 0.735455781 0.76240359 0.803832001 1.763663385 0.613042015 1 11.65341835 -4.261329644 24.5542644 0.806804673 1.763663652 0.865485176 0.116737957 2.214542051 494677.7627 0.019668303 0.151999223 5.48E-05 4.261329644 0.956858978 RS(ph)SDGS(ph)LSHEEDLAK ddPTM_HeLa_Curcumin_4h_R1 1 RSSDGSLSHEEDLAK 15 1 A0A2R8Y7R9;Q13136-2;Q13136;H0YEF9;E9PJZ7 A0A2R8Y7R9 PPFIA1 Liprin-alpha-1 2 0 RS(0.697)S(0.312)DGS(0.753)LS(0.238)HEEDLAK 77.357 0.0076396 125670000 8208.1 6767.1 6703.5 7412.9 7627.1 8588.1 5927.5 2281.3 9051.3 6943.7 TRUE FALSE FALSE 7558.420224 7352.01797 6951.937607 7382.227384 7536.151814 6806.831252 6093.809697 2976.857868 8058.395035 7184.993058 1.051973212 1.023246357 0.96756358 1.027450872 1.048873917 0.947367826 0.848130214 0.41431604 1.121559196 1 12.81077105 -4.110779211 1.461903186 1.021772966 6.59E-24 0.952368806 0.041459551 0.177749224 0.259676954 0.004354749 0.291303685 7.75E-05 4.110779211 -1.021772966 down T(ph)KSREHGIAMRK ddPTM_HeLa_Curcumin_4h_R1 1 TKSREHGIAMRK 12 3 H3BPP2;Q9NRP2 H3BPP2 CMC2 COX assembly mitochondrial protein 2 homolog 1 0 T(0.5)KS(0.5)REHGIAMRK 54.471 0.019882 15120000 1294.3 774.47 1497.3 1221.8 881.54 1440.9 1067.6 1023.1 1169.4 1510.4 TRUE FALSE FALSE 1191.854789 841.4117358 1552.791255 1216.744515 871.0282113 1142.041098 1097.553983 1335.03848 1041.119746 1562.886288 0.762598532 0.538370413 0.993540776 0.77852402 0.557320272 0.73072565 0.702260933 0.854213445 0.666151948 1 10.6099971 -8.951980774 0.656887111 1.013730642 0.732673346 0 0.161715919 0.670000874 0.50734316 0.10218329 0.027908886 1.12E-09 8.951980774 -0.281057296 T(ph)LCLST(ph)PS(ph)S(ph)ST(ph)VK ddPTM_HeLa_Curcumin_4h_R1 1 TLCLSTPSSSTVK 13 0 Q03164-2;Q03164;Q03164-3;A0A3B3ITZ1;E9PR05 Q03164-2 KMT2A Histone-lysine N-methyltransferase 2A;MLL cleavage product N320;MLL cleavage product C180 5 0 T(0.98)LCLS(0.26)T(0.791)PS(0.88)S(0.609)S(0.609)T(0.87)VK 52.5 0.015429 14613000 61.923 0 0 161.09 174.91 134.66 66.163 155.75 141.78 66.762 TRUE FALSE FALSE 57.02172921 0 0 160.4234523 172.8243125 106.7299981 68.01935571 203.237458 126.2270887 69.08197453 0.825421242 0 0 2.322218688 2.501728036 1.544976078 0.984618002 2.941975232 1.827207308 1 6.110237414 -6.248216417 24.84091816 0.7694905 1.99543727 0.47518158 0.695915314 486.5540906 914049.7893 0.095004861 0.156930442 5.65E-07 6.248216417 1.22594677 T(ph)LDELSQGTTTVK ddPTM_HeLa_Curcumin_4h_R1 2 TLDELSQGTTTVK 13 0 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 1 0 T(0.999)LDELS(0.001)QGTTTVK;T(1)LDELSQGTTTVK ; 132.44 0.004317 11296200 1872.51 1425.63 1462.56 1507.37 1701.18 6050.7 6249.2 1344.13 2115.7 1512.84 TRUE FALSE FALSE 1724.298858 1548.855105 1516.76376 1501.132902 1680.89454 4795.716615 6424.535733 1753.949049 1883.613003 1565.411077 1.101499077 0.989423882 0.968923615 0.958938469 1.073771972 3.063550964 4.104056644 1.120439912 1.203270521 1 10.61232584 -5.26548646 23.9828264 1.0330277 2.896820004 0.567855847 0.684738463 85.30945939 505543.889 0.08607807 0.199472546 5.43E-06 5.26548646 1.863792304 T(ph)LGTPTQPGSTPR ddPTM_HeLa_Curcumin_4h_R1 1 TLGTPTQPGSTPR 13 0 Q8NFH5-2;Q8NFH5;Q8NFH5-3 Q8NFH5-2 NUP35 Nucleoporin NUP53 1 0 T(0.7)LGT(0.281)PT(0.018)QPGSTPR 135.04 0.0038119 92559000 2050.8 2124.7 2013.1 1728.6 1700.1 2476.5 2017.1 2286.7 2177.4 1930.9 TRUE FALSE FALSE 1888.477016 2308.349601 2087.707257 1721.447511 1679.827418 1962.845984 2073.694397 2983.904303 1938.544668 1997.998631 0.945184339 1.155330922 1.044899243 0.861585931 0.840755039 0.98240607 1.037885795 1.49344662 0.970243241 1 10.96433988 -4.252255939 3.225009576 0.974929983 1.573539807 0.77354151 0.083621782 0.12932301 2.073445771 0.012126956 0.195410922 5.59E-05 4.252255939 0.598609824 T(ph)LQRLSSGFDDIDLPSAVK ddPTM_HeLa_Curcumin_4h_R1 1 TLQRLSSGFDDIDLPSAVK 19 1 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 0 T(0.733)LQRLS(0.178)S(0.089)GFDDIDLPSAVK 86.617 0.0023301 62792000 2808.3 1910.4 1932.5 1926.7 2354.3 4204.5 2755.4 290.52 3402.9 2570.2 TRUE FALSE FALSE 2586.020092 2075.526463 2004.12015 1918.727826 2326.22651 3332.439306 2832.709108 379.0982106 3029.610384 2659.514259 0.972365568 0.780415618 0.753566236 0.721457995 0.874680969 1.253025546 1.065122738 0.142544154 1.139159293 1 11.37694706 -4.256620652 24.88036454 0.953842235 0.142543799 0.686091398 0.16406289 208.1808061 1074853.137 0.022734194 0.248652366 5.54E-05 4.256620652 -0.811298436 T(ph)LRDSPNVEAAHLAR ddPTM_HeLa_Curcumin_4h_R1 1 TLRDSPNVEAAHLAR 15 1 Q9UHF7;Q9UHF7-3;Q9UHF7-2;E5RFF3;H0YC29;E5RJ97 Q9UHF7 TRPS1 Zinc finger transcription factor Trps1 1 0 T(0.811)LRDS(0.189)PNVEAAHLAR 103.83 0.00098925 11857000 6872.1 5916.3 6217.8 7258.9 6272.3 8497.8 7392.7 4590.8 8819.4 6696.2 TRUE FALSE FALSE 6328.166034 6427.678609 6448.237138 7228.864595 6197.506919 6735.26049 7600.119266 5990.513787 7851.933885 6928.892452 0.913301235 0.927663209 0.930630282 1.043292943 0.894444092 0.972054414 1.096873608 0.864570179 1.133216303 1 12.75840905 T(ph)LS(ph)KSVQTISRY(ph)Y(ph)RK ddPTM_HeLa_Curcumin_4h_R1 1 TLSKSVQTISRYYRK 15 3 J3QKX2;Q2M243 J3QKX2 CCDC27 Coiled-coil domain-containing protein 27 4 0 T(0.905)LS(0.547)KS(0.547)VQT(0.016)IS(0.131)RY(0.921)Y(0.933)RK 51.009 0.016237 20941000 1083.7 1692.6 1366.7 1279.8 1406.4 1621.8 1463 1106.1 1901.2 2454.6 TRUE FALSE FALSE 997.9240015 1838.900802 1417.351104 1274.504527 1389.629599 1285.420399 1504.047843 1443.344798 1692.643117 2539.897167 0.392899372 0.724006005 0.558034838 0.501793751 0.547120417 0.506091512 0.592168794 0.56826899 0.666421908 1 11.31055437 -9.424315131 1.053038991 1.010635834 0.53924257 0.343912528 0.127157467 0.183150434 0.349850246 0.06645758 0.015266382 3.76E-10 9.424315131 -0.471393263 T(ph)LS(ph)LLT(ph)FT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 TLSLLTFTK 9 0 J3KP02 J3KP02 LEKR1 4 0 T(1)LS(1)LLT(1)FT(1)K 48.004 0.0093796 0 725.16 642.52 673.34 624.74 617.02 740.5 807.15 603.23 726.32 762.31 TRUE FALSE FALSE 667.7628208 698.0565658 698.2945727 622.1549914 609.6624395 586.9119528 829.7964567 787.1520501 646.6445132 788.8002158 0.846555069 0.884959907 0.88526164 0.788735828 0.772898419 0.744056532 1.051972908 0.997910541 0.819782374 1 9.623516136 -9.281234915 0.874079788 1.004973507 0.866843624 0 0.106412077 0.846148061 1.092964057 0.078721731 0.018488451 5.23E-10 9.281234915 -0.138129884 T(ph)LSDESIYNSQR ddPTM_HeLa_Curcumin_4h_R1 1 TLSDESIYNSQR 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 T(0.996)LS(0.004)DESIYNSQR 238.07 9.14E-26 318560000 855.12 505.81 640.76 707.37 527.88 1010.2 473.07 522.88 810.69 603.3 TRUE FALSE FALSE 787.4363497 549.5299626 664.5071293 704.4430904 521.5853758 800.6731327 486.343071 682.303705 721.7593352 624.2646301 1.261382292 0.880283675 1.064463846 1.128436654 0.835519667 1.282586093 0.779065556 1.09297191 1.156175283 1 9.286013917 -7.259133891 24.99738918 1.123430525 1.010771313 0.129401261 0.15301437 369.7920326 4009495.14 0.026319191 0.031442415 5.51E-08 7.259133891 -0.112659212 T(ph)LSESFSR ddPTM_HeLa_Curcumin_4h_R1 1 TLSESFSR 8 0 O94921 O94921 CDK14 Cyclin-dependent kinase 14 1 0 T(0.7)LS(0.132)ES(0.168)FSR 131.12 0.014759 11383000 1754.1 1482.8 1332.8 1572.4 1666.9 2623.4 2279 2040.8 2199.2 1562.8 TRUE FALSE FALSE 1615.261134 1610.966625 1382.19474 1565.893825 1647.023306 2079.277268 2342.942606 2663.030525 1957.953262 1617.107184 0.998858425 0.996202751 0.854732917 0.968330264 1.018499777 1.285800527 1.44884806 1.646786652 1.210775193 1 10.65919959 -4.87363163 1.463392379 0.983624498 1.642314536 0.865187275 0.087214104 0.074225344 0.268040808 0.007851426 0.050941941 1.34E-05 4.87363163 0.658690038 T(ph)LSMIEEEIR ddPTM_HeLa_Curcumin_4h_R1 1 TLSMIEEEIR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 T(0.967)LS(0.033)MIEEEIR 147.58 0.0028228 204370000 3615.2 2798.5 2700.7 2906.7 2791.7 3793.5 3221.7 2282.5 3382.9 3174.4 TRUE FALSE FALSE 3329.053105 3040.38987 2800.790318 2894.672846 2758.410801 3006.685338 3312.092231 2978.423743 3011.804334 3284.710164 1.013499803 0.925618919 0.852675024 0.881256702 0.839772967 0.915357882 1.00833622 0.906753897 0.916916313 1 11.68155036 -7.177154577 4.300811217 1.006422122 0.901842264 0.249467289 0.051465868 0.132927926 4.50572285 0.007738755 0.0094901 6.65E-08 7.177154577 -0.104579858 SFEVEEVET(ph)PNS(ph)TPPRR ddPTM_HeLa_Curcumin_4h_R1 2 SFEVEEVETPNSTPPRR 17 1 Q9UHD8;Q9UHD8-5;Q9UHD8-2;Q9UHD8-7;K7ENL0;K7EJV0;K7EPY1 Q9UHD8 9-Sep Septin-9 2 0 SFEVEEVET(0.997)PNS(0.608)T(0.394)PPRR;SFEVEEVET(0.995)PNS(0.554)T(0.451)PPRR ; 112.56 0.00075866 29502000 4730.4 4655.3 4741.4 4782.4 5154.3 5290.8 3995.1 1500.68 5485.2 4309.9 TRUE FALSE FALSE 4355.983849 5057.683388 4917.120455 4762.611696 5092.838339 4193.42844 4107.191754 1958.230424 4883.487283 4459.668704 0.976750548 1.134093971 1.102575277 1.067929484 1.141976832 0.940300439 0.920963423 0.439097734 1.095033646 1 12.12272083 -4.110639782 1.837040195 1.022213204 0.070376452 0.871956227 0.070118887 0.380821718 0.93684596 0.010767952 0.705565003 7.75E-05 4.110639782 -0.951836752 down T(ph)LSPTPS(ph)AEGYQDVR ddPTM_HeLa_Curcumin_4h_R1 2 TLSPTPSAEGYQDVR 15 0 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4;A0A494C1P1;A0A494C1G0;H0Y7N6;F6XFR5 F8W8M4 ABLIM1 Actin-binding LIM protein 1 2 0 T(0.982)LS(0.02)PT(0.205)PS(0.793)AEGYQDVR;T(0.998)LS(0.002)PTPS(1)AEGYQDVR ; 180.39 0.00025513 121247000 10892.3 8725.8 9890.5 9106.8 8033.1 6886.8 4404.2 4931.7 8842 8710.1 TRUE FALSE FALSE 10030.16296 9480.019271 10257.05063 9069.118475 7937.310529 5458.40005 4527.769999 6435.352627 7872.054722 9012.775327 1.112882836 1.051842404 1.138056843 1.006251476 0.880673293 0.605629215 0.502372447 0.714025635 0.873432926 1 13.13775571 -5.458048383 2.226759796 1.059527303 0.590032981 0.828765978 0.085352559 0.064589546 0.626767489 0.009915048 0.025562204 3.48E-06 5.458048383 -0.469494322 T(ph)LSPTPSAEGYQDVR ddPTM_HeLa_Curcumin_4h_R1 2 TLSPTPSAEGYQDVR 15 0 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4;A0A494C1P1;A0A494C1G0;H0Y7N6;F6XFR5 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 T(0.646)LS(0.354)PTPSAEGYQDVR;T(0.997)LS(0.003)PTPSAEGYQDVR ; 249.36 4.75E-30 1102031000 5262.8 4399.5 4890.2 3914.2 4233.1 3813 2390.9 2404.8 5043.7 4336.3 TRUE FALSE FALSE 4846.243827 4779.773176 5071.435114 3898.004078 4182.623047 3022.140819 2457.982219 3138.01245 4490.418729 4486.986102 1.080066601 1.065252503 1.13025425 0.868735492 0.932167596 0.673534696 0.547802503 0.699358629 1.000765018 1 12.131531 -5.431055914 1.41164219 1.044106951 0.606598266 0.859965226 0.070058816 0.10583832 0.4014866 0.010519488 0.035004954 3.71E-06 5.431055914 -0.437508685 SDS(ph)SQPMLLR ddPTM_HeLa_Curcumin_4h_R1 1 SDSSQPMLLR 10 0 A0A075B6G3;H0Y304;A0A087WTU7;A0A5H1ZRP8;A0A5H1ZRP7;A0A087WV90;A0A5H1ZRQ1;A0A5H1ZRP9;A0A5H1ZRQ8;P11532;P11532-11;P11532-4;P11532-2;P11532-3;P11532-14;P11532-8;P11532-12;P11532-17;P11532-6;P11532-5;P11532-7;P11532-15;P11532-9;P11532-16;P11532-13;A0A5H1ZRR9 A0A075B6G3 DMD Dystrophin 1 0 S(0.01)DS(0.783)S(0.208)QPMLLR 118.61 0.0048078 33223000 1263.5 940.63 1142.7 1237 1441.7 1800.6 1603.3 2961.7 1122.9 979.81 TRUE FALSE FALSE 1163.492642 1021.933866 1185.049467 1231.881622 1424.508669 1427.135263 1648.284283 3864.708696 999.7206794 1013.858325 1.147588981 1.007965158 1.168851149 1.215043159 1.405037207 1.407627899 1.625754056 3.811882393 0.986055601 1 9.98564035 -2.151000232 1.005398757 1.097038203 200 0.971893858 0.134583819 13.69460418 0.237904833 0.021242725 6032.187631 0.007063172 2.151000232 198.9029618 up T(ph)LT(ph)DYQNKLEDAS(ph)NELNS(ph)MNDVK ddPTM_HeLa_Curcumin_4h_R1 1 TLTDYQNKLEDASNELNSMNDVK 23 1 Q6TFL3-4 Q6TFL3-4 4 0 T(0.667)LT(0.667)DY(0.667)QNKLEDAS(0.999)NELNS(1)MNDVK 45.696 0.012025 4961300 2426.9 1853.6 2089.1 2451.8 1612.6 1957.9 1895.9 1694.2 2497.5 2486 TRUE FALSE FALSE 2234.808304 2013.816925 2166.523884 2441.655101 1593.370798 1551.80947 1949.093851 2210.753781 2223.530498 2572.388315 0.868767865 0.782858837 0.84222272 0.949178274 0.619413014 0.603256305 0.757698144 0.859416818 0.864383688 1 11.32889273 -7.604404506 0.359936688 1.012864495 0.715877227 0.280398117 0.103087001 0.767038224 0.291708219 0.084144283 0.070324309 2.49E-08 7.604404506 -0.296987268 T(ph)LT(ph)FALR ddPTM_HeLa_Curcumin_4h_R1 1 TLTFALR 7 0 Q96C86;A0A3B3ITF0 Q96C86 DCPS m7GpppX diphosphatase 2 0 T(1)LT(1)FALR 42.914 0.018578 2435500 665.22 512.74 577.78 612.95 678.78 620.11 758.26 407.58 595.66 582.09 TRUE FALSE FALSE 612.5671351 557.0589609 599.1930351 610.4137753 670.6859918 491.4921959 779.5347348 531.8492657 530.3175883 602.3175842 1.017016855 0.924859203 0.994812456 1.013441731 1.113508902 0.816001739 1.294225431 0.883004713 0.88046174 1 9.234380568 -5.991899751 24.7794935 0.999965903 1.034837496 0.014266283 0.128317235 709.282828 2169747.793 0.015928705 0.028836878 1.02E-06 5.991899751 0.034871593 T(ph)LT(ph)S(ph)GSRESNMS(ph)S(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 TLTSGSRESNMSSK 14 1 Q68DU8 Q68DU8 KCTD16 BTB/POZ domain-containing protein KCTD16 5 0 T(0.998)LT(0.987)S(0.954)GS(0.324)RES(0.307)NMS(0.729)S(0.701)K 50.534 0.015456 17212000 1765.8 1552.5 2129 2037.1 1815.2 2113.7 2041.6 1604.5 2019.8 2043.4 TRUE FALSE FALSE 1626.035067 1686.691182 2207.902613 2028.67102 1793.554926 1675.294794 2098.881801 2093.704664 1798.232993 2114.407998 0.769026162 0.797713206 1.044217869 0.959451072 0.848253945 0.792323334 0.992656953 0.990208449 0.850466417 1 11.04603807 -6.78612924 24.99980587 0.880890294 0.930637407 0.142995414 0.090326345 670.4292304 678843.3912 0.0186979 0.024579567 1.64E-07 6.78612924 0.049747113 T(ph)MPT(ph)LMMRT(ph)EDRPK ddPTM_HeLa_Curcumin_4h_R1 1 TMPTLMMRTEDRPK 14 2 Q8N7H5-2;Q8N7H5-3 Q8N7H5-2 PAF1 RNA polymerase II-associated factor 1 homolog 3 0 T(1)MPT(1)LMMRT(1)EDRPK 49.188 0.0094508 0 271.19 238.55 189.74 347.05 0 188.78 207.82 228.35 313.25 227.36 TRUE FALSE FALSE 249.7250253 259.169199 196.7719313 345.6139991 0 149.6249 213.6508699 297.9728638 278.8872587 235.2607431 1.06148192 1.101625353 0.836399345 1.469067871 0 0.635996036 0.90814501 1.266564323 1.185438994 1 7.878116794 -5.807491642 24.99999985 1.047207508 0.712576777 0.252216545 0.332519412 149.5326172 81175.04203 0.046876553 0.084971189 1.56E-06 5.807491642 -0.334630731 T(ph)MSSAKKTDY(ph)MYDEEYLES(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 TMSSAKKTDYMYDEEYLESK 20 2 Q8WZ42-6 Q8WZ42-6 TTN Titin 3 0 T(0.445)MS(0.445)S(0.105)AKKT(0.006)DY(0.71)MY(0.272)DEEY(0.212)LES(0.805)K 62.658 0.0053769 6467000 2093.8 1603.4 1931.5 1703.1 1975.5 2238.3 1608.6 1483.3 2100.5 1503.4 TRUE FALSE FALSE 1928.073521 1741.990751 2003.083089 1696.053023 1951.943453 1774.051349 1653.732987 1935.551342 1870.080405 1555.643038 1.239406132 1.119788222 1.287623857 1.090258486 1.254750225 1.140397447 1.063054278 1.244213032 1.20212694 1 10.60329534 -9.415917508 1.084425285 0.997604455 1.1812308 0 0.094596781 0.350337243 0.721380669 0.049883239 0.011956569 3.84E-10 9.415917508 0.183626345 T(ph)MSSDDEDCSAK ddPTM_HeLa_Curcumin_4h_R1 1 TMSSDDEDCSAK 12 0 H0YBW3;Q9NVR2 H0YBW3 INTS10 Integrator complex subunit 10 1 0 T(0.734)MS(0.162)S(0.104)DDEDCSAK 164.13 2.91E-08 0 3625.3 3208.6 3098.6 2927.9 3102.6 3338 2678.5 1926.7 3335.5 3001.4 TRUE FALSE FALSE 3338.35368 3485.937087 3213.436842 2915.785126 3065.603521 2645.661173 2753.651501 2514.141961 2969.603995 3105.698427 1.074912378 1.122432576 1.034690559 0.938850051 0.987089891 0.851873173 0.886644845 0.809525464 0.956179122 1 11.60070203 -5.479524061 1.064073429 1.042951175 0.83339403 0.702391105 0.050969411 0.217841125 0.450330671 0.007935338 0.03132228 3.31E-06 5.479524061 -0.209557145 TVLPTVPES(ph)PEEEVK ddPTM_HeLa_Curcumin_4h_R1 3 TVLPTVPESPEEEVK 15 0 O75152;E9PBY7;E9PQ61;A0A1W2PPR9 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 0 TVLPTVPES(1)PEEEVK;TVLPTVPES(1)PEEEVK;TVLPT(0.001)VPES(0.999)PEEEVK ;; 187.08 1.25E-05 120182000 16836.8 13963.1 15602.8 16063.8 19189.1 21131.3 19430.9 31700.5 17030.6 13707.3 TRUE FALSE FALSE 15504.14951 15170.00815 16181.05349 15997.33225 18960.28252 16748.43018 19976.07876 41365.83652 15162.38579 14183.62765 1.093101842 1.069543597 1.140826162 1.127873111 1.336772438 1.180828388 1.408389958 2.916449693 1.069006192 1 13.79193895 -2.138686558 1.087899401 1.07192023 200 0.968320357 0.096223756 21.30931903 0.299068275 0.015974514 10279.92753 0.007266302 2.138686558 198.9280798 up T(ph)NSPAYS(ph)DIS(ph)DAGEDGEGKVDSVK ddPTM_HeLa_Curcumin_4h_R1 1 TNSPAYSDISDAGEDGEGKVDSVK 24 1 O15014 O15014 ZNF609 Zinc finger protein 609 3 0 T(0.5)NS(0.5)PAY(0.287)S(0.764)DIS(0.949)DAGEDGEGKVDSVK 58.107 0.0046186 0 863.75 949.84 1126 737.26 981.71 649.54 725.14 410.19 922.55 745.4 TRUE FALSE FALSE 795.3832761 1031.939937 1167.730551 734.2094135 970.0037494 514.8180822 745.4854768 535.2550427 821.3485731 771.3025945 1.031220797 1.337918405 1.513972025 0.951908393 1.257617641 0.667465773 0.9665279 0.693962456 1.064885013 1 9.591153154 -5.256338557 24.94679133 1.087500434 0.795039629 0.433530396 0.189511843 401.7397299 1964795.231 0.028670766 0.070710507 5.54E-06 5.256338557 -0.292460804 T(ph)NSTGGSSGSSVGGGSGK ddPTM_HeLa_Curcumin_4h_R1 1 TNSTGGSSGSSVGGGSGK 18 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-5;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 0 T(0.9)NS(0.012)T(0.087)GGSSGSSVGGGSGK 140.89 2.32E-05 0 136.48 144.45 245.83 178.99 229.72 165.38 227.95 0 267.94 157.36 TRUE FALSE FALSE 125.677464 156.9356143 254.9406761 178.2493868 226.980739 131.0783238 234.3456635 0 238.5476524 162.8282483 0.771840668 0.963810739 1.565702995 1.094708005 1.393988705 0.805009728 1.439219951 0 1.465026215 1 7.347207197 -2.899326531 13.00881829 0.967870442 0.996139939 0 0.45024169 0 0 0.051184044 0 0.001260879 2.899326531 0.028269497 ARQPLSEASNQQPLS(ph)GGEEK ddPTM_HeLa_Curcumin_4h_R1 4 ARQPLSEASNQQPLSGGEEK 20 1 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 0 ARQPLSEASNQQPLS(1)GGEEK;ARQPLSEAS(0.006)NQQPLS(0.994)GGEEK;ARQPLS(0.001)EAS(0.08)NQQPLS(0.919)GGEEK;ARQPLSEASNQQPLS(1)GGEEK ;;; 105.82 0.00014577 161997000 14708.2 11693.6 13531.1 13992.6 14280.4 14769 11497.9 4151.38 14860.4 14272.5 TRUE FALSE FALSE 13544.03045 12704.34268 14032.57447 13934.70233 14110.11556 11705.74292 11820.50013 5417.116651 13230.2513 14768.46831 0.917091073 0.860234278 0.950171282 0.94354418 0.955421731 0.792617262 0.800387683 0.366802876 0.895844513 1 13.85023259 -4.109824054 1.199952987 0.948507461 5.82E-19 0.901630953 0.054170341 0.435801092 0.409838204 0.008276793 0.558259688 7.77E-05 4.109824054 -0.948507461 down T(ph)PASTPVSGTPQAS(ph)PMIER ddPTM_HeLa_Curcumin_4h_R1 3 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2 0 T(0.617)PAS(0.028)T(0.037)PVS(0.082)GT(0.241)PQAS(0.995)PMIER;T(0.501)PAS(0.49)T(0.008)PVS(0.001)GT(0.002)PQAS(0.998)PMIER;T(0.819)PAS(0.122)T(0.053)PVS(0.01)GT(0.013)PQAS(0.984)PMIER ;; 155.16 0.00014972 139282700 4635.65 3990.26 4387.25 4491.07 4278.39 4671.7 3220.44 1849.13 4584.8 3955.97 TRUE FALSE FALSE 4268.733411 4335.160294 4549.845344 4472.487142 4227.372994 3702.736759 3310.796879 2412.921225 4081.858911 4093.439663 1.042823093 1.059050738 1.111496863 1.09259877 1.032719019 0.904553887 0.808805589 0.589460557 0.997170899 1 11.99909791 -4.473684647 1.26347593 1.037087583 0.493840827 0.932052191 0.039408146 0.205372142 0.360833984 0.006819197 0.130044572 3.36E-05 4.473684647 -0.543246757 T(ph)PCEEILVK ddPTM_HeLa_Curcumin_4h_R1 1 TPCEEILVK 9 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 T(1)PCEEILVK 118.28 0.019368 16304000 2004.1 1890.2 2130 1684.3 2208 2420.5 2137.7 1628.8 1925.4 1574.1 TRUE FALSE FALSE 1845.47337 2053.580465 2208.939674 1677.330813 2181.671042 1918.461015 2197.678109 2125.413622 1714.188437 1628.799858 1.13302648 1.260793618 1.356176244 1.02979553 1.339434696 1.17783717 1.349262218 1.30489551 1.052424231 1 10.66959363 -8.022446275 0.297528908 0.943229902 1.314590873 0.477441851 0.096046674 0.983087671 0.245410129 0.144639811 0.081399309 9.50E-09 8.022446275 0.371360971 T(ph)PDTIRR ddPTM_HeLa_Curcumin_4h_R1 2 TPDTIRR 7 1 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 1 0 T(1)PDTIRR;T(1)PDTIRR ; 97.602 0.011083 9748200 2673.8 2635.19 2495.09 2237.59 1789.76 2710.9 1715.21 1577.17 2277.45 2682.7 TRUE FALSE FALSE 2462.165909 2862.964081 2587.56023 2228.331445 1768.418281 2148.628782 1763.334176 2058.041873 2027.619433 2775.923625 0.886971776 1.031355494 0.932143884 0.802735142 0.637055813 0.774023018 0.635224312 0.741389948 0.730430555 1 11.43875216 -6.107016498 2.902151917 0.952461683 0.69848173 0.559240004 0.088643438 0.08532655 1.388612686 0.009084083 0.016086714 7.82E-07 6.107016498 -0.253979953 T(ph)PDTSTYCYETAEK ddPTM_HeLa_Curcumin_4h_R1 3 TPDTSTYCYETAEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(1)PDTSTYCYETAEK;T(1)PDTSTYCYETAEK;T(1)PDTSTYCYETAEK ;; 252.46 4.94E-38 475881000 4436.9 4143.8 4495.1 4697.9 4523.4 5439.8 3706.48 3139.31 4498.8 3988.28 TRUE FALSE FALSE 4085.714683 4501.971608 4661.69236 4678.461335 4469.461409 4311.524161 3810.473853 4096.471167 4005.292895 4126.872433 0.990026891 1.090891875 1.12959449 1.133657851 1.083014191 1.044743745 0.923332115 0.99263334 0.970539545 1 12.01083313 -3.292271635 13.48011538 1.022176893 1.045705879 0 0.069089577 0 0 0.010107827 0 0.000510186 3.292271635 0.023528987 T(ph)PEDGDYSYEIIEK ddPTM_HeLa_Curcumin_4h_R1 2 TPEDGDYSYEIIEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(1)PEDGDYSYEIIEK;T(1)PEDGDYSYEIIEK ; 214.58 2.62E-13 29481000 2523.08 2770.5 2473.76 2443.88 2754.2 2660.99 2001.55 2783.4 2177.27 2381.4 TRUE FALSE FALSE 2323.375556 3009.969675 2565.439722 2433.767872 2721.357964 2109.070678 2057.708106 3632.045847 1938.428928 2464.153473 0.942869663 1.221502519 1.041103872 0.98766895 1.104378438 0.855900698 0.835056797 1.473952774 0.786651055 1 11.2668764 -4.249926792 24.7271578 0.988650705 1.47395311 0.589878145 0.124341233 717.7314777 1541537.512 0.014704447 0.307730117 5.62E-05 4.249926792 0.485302405 T(ph)PEEGGYSYDISEK ddPTM_HeLa_Curcumin_4h_R1 4 TPEEGGYSYDISEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK;T(1)PEEGGYSYDISEK ;;; 161.49 0.00078452 513226500 11110.4 10065.9 10657.8 10431.8 11841.3 11225.8 9452.2 7050.46 10698.8 8682.2 TRUE FALSE FALSE 10231.00012 10935.95154 11052.78744 10388.63598 11700.10023 8897.442539 9717.403293 9200.112798 9525.168407 8983.905804 1.138814269 1.217282525 1.230287548 1.156360741 1.302340039 0.99037576 1.081645723 1.024066035 1.060248027 1 13.13312709 -1.002680937 24.97849515 1.10131288 0.001414803 0 0.102734367 0 0 0.015120645 0 0.099384593 1.002680937 -1.099898077 T(ph)PELPEPSVK ddPTM_HeLa_Curcumin_4h_R1 1 TPELPEPSVK 10 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 T(1)PELPEPSVK 119.03 0.013726 64630000 5498 4153.1 4590.5 5209.2 4778.7 5508.6 4807.8 4339.7 5009 5049.2 TRUE FALSE FALSE 5062.827499 4512.075458 4760.627968 5187.645711 4721.717124 4366.054265 4942.693928 5662.854552 4459.525232 5224.659324 0.969025382 0.86361142 0.91118438 0.992915593 0.903736843 0.835662958 0.946031812 1.083870584 0.853553305 1 12.35112125 -7.490822957 10.3424346 0.98638004 0.929753403 0 0.077514467 0.776150354 245.4970318 0.011300913 0.012522741 3.23E-08 7.490822957 -0.056626637 T(ph)PENLITEIR ddPTM_HeLa_Curcumin_4h_R1 2 TPENLITEIR 10 0 Q5VY60;Q7Z4H7-3;Q7Z4H7;Q5SYF9 Q5VY60 HAUS6 HAUS augmin-like complex subunit 6 1 0 T(1)PENLITEIR;T(1)PENLITEIR ; 152 0.001915 40244000 859.29 841.14 1196 773.25 893.23 1046.45 1153.11 1432.71 766.69 1077.88 TRUE FALSE FALSE 791.2762898 913.8443936 1240.324812 770.0504964 882.5788156 829.4044741 1185.463163 1869.536684 682.5860252 1115.33625 0.709450885 0.819344295 1.11206357 0.690420038 0.791311872 0.743636257 1.062875132 1.676209021 0.612000215 1 10.123263 -4.30664291 2.82272908 0.851354259 1.782776002 0.759631989 0.145869477 0.137021329 1.588015614 0.020105619 0.277212418 4.94E-05 4.30664291 0.931421743 T(ph)PEPSSPVKEPPPVLAKPK ddPTM_HeLa_Curcumin_4h_R1 1 TPEPSSPVKEPPPVLAKPK 19 2 Q86TC9;A0A087WX60;Q86TC9-2 Q86TC9 MYPN Myopalladin 1 0 T(0.877)PEPS(0.061)S(0.061)PVKEPPPVLAKPK 64.761 0.0065126 386400000 3417 2863.8 3235.8 3068.8 2694.6 3889.3 3268.4 2464.6 3848.2 3140.1 TRUE FALSE FALSE 3146.540844 3111.334111 3355.721594 3056.102119 2662.468655 3082.615339 3360.102508 3216.045194 3426.062088 3249.218241 0.968399354 0.957563906 1.032778147 0.940565358 0.819418228 0.948725235 1.034126445 0.989790453 1.054426583 1 11.66587693 T(ph)PETLLPFAEAEAFLKK ddPTM_HeLa_Curcumin_4h_R1 2 TPETLLPFAEAEAFLKK 17 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;Q3KQU3-3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 1 0 T(0.992)PET(0.008)LLPFAEAEAFLKK;T(0.987)PET(0.013)LLPFAEAEAFLKK ; 152.07 0.00010409 45671000 2450.13 1848.2 2174.84 2385.58 2212.9 1739.44 1296.47 2901.4 2106.68 1765.74 TRUE FALSE FALSE 2256.199625 2007.950173 2255.441484 2375.709102 2186.512613 1378.660536 1332.845459 3786.023504 1875.582475 1827.099334 1.234853291 1.098982489 1.234438348 1.300262694 1.196712501 0.754562443 0.729487135 2.072149792 1.02653558 1 10.83533936 -9.417886628 1.073759898 0.997109408 1.177985953 0.041506206 0.347631691 1.752960616 3.521161962 0.24518124 0.058011191 3.82E-10 9.417886628 0.180876546 T(ph)PFNTDLGENSGIGK ddPTM_HeLa_Curcumin_4h_R1 1 TPFNTDLGENSGIGK 15 0 Q6P0N0 Q6P0N0 MIS18BP1 Mis18-binding protein 1 1 0 T(0.891)PFNT(0.005)DLGENS(0.104)GIGK 217.39 7.45E-14 6894900 2332.8 2081.5 1749.6 2080.6 1899 2938.9 2404.2 667 2471 1730.3 TRUE FALSE FALSE 2148.156418 2261.415585 1814.441715 2071.991028 1876.355665 2329.339012 2471.655381 870.3652295 2199.937482 1790.427796 1.199800641 1.263058801 1.013412392 1.157260311 1.047992926 1.300995783 1.380483137 0.486121379 1.228721698 1 10.80608862 -4.247272732 24.99975049 1.131145695 0.486120942 0.717943895 0.127008102 1171.29788 2066945.291 0.018771482 0.537480973 5.66E-05 4.247272732 -0.645024753 T(ph)PHTPGTPK ddPTM_HeLa_Curcumin_4h_R1 1 TPHTPGTPK 9 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 T(0.952)PHT(0.045)PGT(0.002)PK 119.62 0.018364 9489600 4493.7 3886 3961.1 4260.5 4274.9 4675.7 3619.9 3001.3 4727.4 4346.8 TRUE FALSE FALSE 4138.018903 4221.888524 4107.901851 4242.87118 4223.92461 3705.907114 3721.464652 3916.382554 4208.816047 4497.850976 0.919999112 0.93864571 0.913303236 0.94331075 0.93909839 0.82392839 0.827387273 0.870723057 0.935739327 1 12.13502015 -1 0.093689182 1.061180224 0.43002538 0.559097967 0.03476458 58.68189944 0.396149913 0.340244995 4.78028049 0.1 1 -0.631154844 T(ph)PKDSPGIPPSANAHQLFR ddPTM_HeLa_Curcumin_4h_R1 2 TPKDSPGIPPSANAHQLFR 19 1 B4DG22;B1AXG1;B7ZB17;P51812 B4DG22 RPS6KA3 Ribosomal protein S6 kinase alpha-3 1 0 T(0.626)PKDS(0.374)PGIPPSANAHQLFR;T(0.626)PKDS(0.374)PGIPPSANAHQLFR ; 80.459 0.0015074 100412000 5073.5 4111.6 3455.3 4227.8 5802.1 7664.3 3760.3 2005.47 5892.3 4278.4 TRUE FALSE FALSE 4671.927121 4466.988383 3583.356458 4210.306484 5732.913747 6074.637786 3865.803898 2616.928571 5245.929432 4427.074082 1.055308096 1.009015955 0.80941868 0.951035923 1.294966753 1.372156344 0.873218705 0.591119218 1.18496536 1 12.1121378 -4.505314584 7.629010104 1.045084582 0.657364669 0.458821603 0.161648564 0.126867447 37.70351573 0.022381507 0.105198627 3.12E-05 4.505314584 -0.387719913 T(ph)PLCNLLVK ddPTM_HeLa_Curcumin_4h_R1 2 TPLCNLLVK 9 0 H7C3M5;A0A1B0GW05;Q2PZI1-2;Q2PZI1 H7C3M5 DPY19L1 Probable C-mannosyltransferase DPY19L1 1 0 T(1)PLCNLLVK;T(1)PLCNLLVK ; 128.6 0.011997 882110000 4059.8 3077.7 3250 3565.8 3668.9 4626.1 3800.4 3617.5 4019.7 3972.1 TRUE FALSE FALSE 3738.462546 3343.722674 3370.447859 3551.045664 3625.150764 3666.594713 3907.028996 4720.459097 3578.748967 4110.130179 0.909572783 0.813532061 0.820034333 0.863974013 0.88200388 0.892087246 0.950585219 1.148493817 0.870714262 1 12.00496837 -4.269494212 3.671507283 0.920795098 1.171550807 0.591500455 0.06013787 0.190014327 4.72667337 0.010665602 0.128155828 5.38E-05 4.269494212 0.250755709 T(ph)PPAPSPFDLPELK ddPTM_HeLa_Curcumin_4h_R1 2 TPPAPSPFDLPELK 14 0 O95239 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 0 T(1)PPAPSPFDLPELK;T(1)PPAPSPFDLPELK ; 115.06 0.0063836 37324300 2493 1881.44 2369.5 2468.2 2603.9 2611.3 2245 1057.72 2185.31 1923.21 TRUE FALSE FALSE 2295.676419 2044.06329 2457.315754 2457.987242 2572.850193 2069.686945 2307.988658 1380.213959 1945.58696 1990.041404 1.153582239 1.027146111 1.234806346 1.23514377 1.292862645 1.040022052 1.159769165 0.693560423 0.977661548 1 10.95858273 -4.257169085 24.7617066 1.109395194 0.693560235 0.598879684 0.105161598 220.3216805 1277500.277 0.01532866 0.160083531 5.53E-05 4.257169085 -0.415834959 T(ph)PPMMPGS(ph)QR ddPTM_HeLa_Curcumin_4h_R1 1 TPPMMPGSQR 10 0 Q96RT1-7;Q96RT1-6;Q96RT1-4;Q96RT1-5;Q96RT1-3;Q96RT1-9;Q96RT1-2;Q96RT1;Q96RT1-8;H0YA04 Q96RT1-7 ERBB2IP Protein LAP2 2 0 T(1)PPMMPGS(1)QR 64.841 0.013333 3952800 1153.8 977.9 1182.8 1241.1 1080 1117.9 828.71 821.89 1281.7 1116.5 TRUE FALSE FALSE 1062.475513 1062.425319 1226.635608 1235.964657 1067.121705 886.0349387 851.9613722 1072.480477 1141.100717 1155.298292 0.919654707 0.919611261 1.061747963 1.069822976 0.923676346 0.766931748 0.737438442 0.928314778 0.987710901 1 10.17404968 -5.411807785 4.776210694 0.973478654 0.805088537 0.584400474 0.067319517 0.133393559 4.727908278 0.01021676 0.023327086 3.87E-06 5.411807785 -0.168390116 T(ph)PPSEEDSAEAER ddPTM_HeLa_Curcumin_4h_R1 1 TPPSEEDSAEAER 13 0 O43765;K7EMD6 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 0 T(0.998)PPS(0.002)EEDSAEAER 102.33 0.016947 6726200 361.54 429.4 439.05 407.24 390.87 282.25 333.58 315.44 379.1 268.03 TRUE FALSE FALSE 332.9237275 466.5154226 455.3215792 405.5549488 386.2091305 223.7081684 342.939357 411.6162039 337.5136785 277.3440225 1.200399866 1.682082124 1.641721264 1.462281195 1.392527328 0.806608941 1.236512523 1.48413584 1.216949532 1 8.115532822 -7.758566953 2.179566676 1.067743128 1.371302498 0.167805467 0.238640626 0.315013065 3.120251308 0.051288848 0.050518871 1.74E-08 7.758566953 0.303559371 T(ph)PS(ph)PPPPIPEDIALGKK ddPTM_HeLa_Curcumin_4h_R1 1 TPSPPPPIPEDIALGKK 17 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 2 0 T(1)PS(1)PPPPIPEDIALGKK 87.228 0.0042661 4557800 1650.8 1515.2 1681.6 1904.5 1623.2 2473.2 1716 2365.8 2024.4 1594.7 TRUE FALSE FALSE 1520.137438 1646.167136 1743.921575 1896.619684 1603.8444 1960.230441 1764.146342 3087.121529 1802.328385 1650.115706 0.921230816 0.997607095 1.056848055 1.149385874 0.971958751 1.187935145 1.06910463 1.870851551 1.09224364 1 10.68835147 -1.834658676 1.088400377 0.988186384 199.9999999 0.870822825 0.092756105 80.3999546 0.534552504 0.013262223 39422.5186 0.014633268 1.834658676 199.0118135 T(ph)PS(ph)YSIS(ph)S(ph)TLNPQAPEFILGCT(ph)ASK ddPTM_HeLa_Curcumin_4h_R1 1 TPSYSISSTLNPQAPEFILGCTASK 25 0 Q14694;Q14694-3;Q14694-2;H3BQC6 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 5 0 T(0.642)PS(0.642)Y(0.593)S(0.428)IS(0.795)S(0.826)T(0.073)LNPQAPEFILGCT(0.5)AS(0.5)K 53.454 0.0049042 0 2299.1 1859.4 1887.5 2174.9 2114.3 2433.5 1919.6 1641.1 2283.9 1785.6 TRUE FALSE FALSE 2117.123809 2020.118251 1957.45241 2165.90084 2089.088353 1928.764669 1973.45881 2141.463835 2033.361884 1847.649467 1.145847114 1.09334497 1.05942845 1.172246619 1.130673534 1.043901835 1.068091564 1.159020622 1.100512798 1 10.85147536 -9.425221648 1.08883976 0.998399958 1.109659356 0.050605517 0.051123311 0.361873614 0.74954444 0.031401902 0.007452189 3.76E-10 9.425221648 0.111259398 T(ph)PSASNDDQQE ddPTM_HeLa_Curcumin_4h_R1 2 TPSASNDDQQE 11 0 O43765 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 0 T(0.496)PS(0.496)AS(0.007)NDDQQE;T(0.498)PS(0.498)AS(0.003)NDDQQE ; 192.3 9.47E-05 47040000 6112.8 5479.3 5548 5442.1 5487.4 6762.1 5812.6 11910.8 6634.1 6398.8 TRUE FALSE FALSE 5628.96543 5952.906277 5753.613761 5419.582032 5421.966339 5359.564235 5975.685912 15542.34809 5906.355828 6621.157824 0.850148204 0.899073309 0.868973964 0.818524822 0.818884927 0.809460275 0.90251374 2.347376169 0.892042749 1 12.6928678 -4.261465641 9.624875713 0.897683231 2.351788236 0.982942304 0.058176435 0.009108689 22.8438742 0.011027448 0.085669389 5.48E-05 4.261465641 1.454105006 T(ph)PSDDEEDNLFAPPK ddPTM_HeLa_Curcumin_4h_R1 1 TPSDDEEDNLFAPPK 15 0 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q641Q2;F8W7U3;E7ESD2;Q641Q2-2 A0A0A0MR88;Q641Q2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 0 T(0.895)PS(0.105)DDEEDNLFAPPK 164.7 0.00072099 47700000 1586.1 1127.1 1215.7 1102.2 1577.5 1740.6 1468.3 1170.5 1491.7 1382.3 TRUE FALSE FALSE 1460.558511 1224.521502 1260.754911 1097.639388 1558.689343 1379.579939 1509.496546 1527.380062 1328.064242 1430.334822 1.0211305 0.856108292 0.88144041 0.767400312 1.089737395 0.964515383 1.055344891 1.067847918 0.928498853 1 10.48213719 -4.688585474 1.702431374 0.974563323 1.077672166 0.136120521 0.091945435 0.887369585 4.215910269 0.014372177 0.114027756 2.05E-05 4.688585474 0.103108843 T(ph)PSIDLQR ddPTM_HeLa_Curcumin_4h_R1 1 TPSIDLQR 8 0 A0A0U1RR27;Q7Z401;Q7Z401-2 A0A0U1RR27 DENND4A C-myc promoter-binding protein 1 0 T(0.958)PS(0.042)IDLQR 126.31 0.018272 4267900 2371.4 2125.6 2001.7 2012.2 1977.4 2451.3 1917.2 905.35 2415.9 2443 TRUE FALSE FALSE 2183.701188 2309.327393 2075.884763 2003.87405 1953.820796 1942.872748 1970.991472 1181.387047 2150.881814 2527.894068 0.863842048 0.91353804 0.821191358 0.792704914 0.772904538 0.768573641 0.77969702 0.467340409 0.850859156 1 11.30372029 -2.979818201 0.208386911 0.995470375 2.44E-20 0.685443845 0.073717107 7.786810618 0.186646152 0.061924006 2.18773668 0.001047567 2.979818201 -0.995470375 SPSDSSTAS(ph)TPVAEQIER ddPTM_HeLa_Curcumin_4h_R1 2 SPSDSSTASTPVAEQIER 18 0 Q16643-3;Q16643;Q16643-2;D6R9Q9 Q16643-3 DBN1 Drebrin 1 0 SPSDSST(0.019)AS(0.49)T(0.49)PVAEQIER;SPSDS(0.012)S(0.012)T(0.059)AS(0.458)T(0.458)PVAEQIER ; 152.94 6.31E-05 182968000 2698.7 2131.88 2697.6 2399.2 2388 4065.5 3124.7 5474.9 2862.9 2161.26 TRUE FALSE FALSE 2485.095047 2316.150208 2797.575429 2389.272746 2359.52466 3222.269472 3212.370672 7144.171807 2548.847033 2236.363624 1.111221369 1.035676928 1.250948369 1.068373998 1.055072008 1.440852211 1.436425918 3.194548386 1.139728354 1 11.12693907 -2.120397426 1.045413786 1.06920598 199.9999993 0.964215391 0.118306463 17.38286878 0.257802996 0.016894956 8026.878724 0.007578837 2.120397426 198.9307933 up T(ph)PSSDVLVFDYTK ddPTM_HeLa_Curcumin_4h_R1 2 TPSSDVLVFDYTK 13 0 E9PC52;Q16576;Q16576-2;Q5JP01;Q09028-3;Q09028;Q09028-2;Q09028-4;H0YF10 E9PC52;Q09028-3 RBBP7;RBBP4 Histone-binding protein RBBP7;Histone-binding protein RBBP4 1 0 T(0.974)PS(0.026)SDVLVFDYTK;T(0.889)PS(0.108)S(0.003)DVLVFDYTK ; 169.79 2.22E-08 2509400 2194.1 1922.89 1931.54 1833.23 2211.04 3085.3 2015.86 2129.73 1675.79 1658.26 TRUE FALSE FALSE 2020.43467 2089.096043 2003.124572 1825.64458 2184.674792 2445.374002 2072.419606 2779.074873 1491.96003 1715.884412 1.177488796 1.217503947 1.167400647 1.063967111 1.27320627 1.425139121 1.207785089 1.619616598 0.869499145 1 10.74473666 -1 0.212086831 1.029006887 3.411302768 0.671797889 0.114828278 22.33059129 0.263113536 0.081488866 18.15899311 0.1 1 2.382295881 T(ph)PSSEEIS(ph)PTKFPGLYR ddPTM_HeLa_Curcumin_4h_R1 1 TPSSEEISPTKFPGLYR 17 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 2 0 T(0.611)PS(0.284)S(0.107)EEIS(0.99)PT(0.009)KFPGLYR 93.255 0.0053845 23304000 3285 2942.5 3279.9 3183.3 3007.7 4180 3650 3479.1 3885.2 3337.6 TRUE FALSE FALSE 3024.988784 3196.836588 3401.455979 3170.128348 2971.835142 3313.020882 3752.409177 4539.861574 3459.00328 3453.581352 0.875899096 0.9256584 0.984906864 0.917924909 0.86050822 0.959300084 1.08652694 1.31453732 1.001569944 1 11.75387749 -4.374046766 1.957189135 0.935027205 1.378556391 0.864538197 0.045806356 0.176250009 0.847050806 0.007703004 0.128736927 4.23E-05 4.374046766 0.443529186 T(ph)PSSEEISPT(ph)KFPGLYR ddPTM_HeLa_Curcumin_4h_R1 1 TPSSEEISPTKFPGLYR 17 1 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 2 0 T(0.597)PS(0.333)S(0.07)EEIS(0.078)PT(0.922)KFPGLYR 121.03 0.00053663 6603800 2902.1 2393.2 2473.4 2723.7 2529.9 3304 2362.3 2207.9 2738.7 2322.7 TRUE FALSE FALSE 2672.395723 2600.057544 2565.06638 2712.430051 2499.732595 2618.713156 2428.57978 2881.078546 2438.271462 2403.413652 1.111916678 1.08181858 1.067259636 1.128573955 1.040075891 1.089580711 1.010470993 1.198744354 1.014503458 1 11.23086926 -9.375539094 1.006836461 0.998005915 1.088626438 0.321988593 0.048384425 0.49878891 0.872596705 0.033468209 0.00790539 4.21E-10 9.375539094 0.090620523 T(ph)PSSEEISPTK ddPTM_HeLa_Curcumin_4h_R1 2 TPSSEEISPTK 11 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 0 T(0.841)PS(0.08)S(0.08)EEISPTK;T(0.833)PS(0.164)S(0.003)EEISPTK ; 171.49 0.00067277 63520000 5562 5268 5180.8 5960.1 5983.8 5911.9 5227.1 3129.5 4891.5 4142 TRUE FALSE FALSE 5121.761831 5723.342446 5372.805005 5935.438685 5912.447093 4685.705299 5373.758358 4083.670144 4354.914688 4285.934192 1.195016443 1.335378051 1.253590178 1.384864634 1.379500204 1.093275139 1.253812615 0.952807477 1.016094623 1 12.06539398 -8.624957773 0.84988288 1.014643087 1.240667863 0.33090071 0.125392085 0.473825111 0.692199189 0.056136842 0.026450791 2.37E-09 8.624957773 0.226024776 ATGDGS(ph)S(ph)PELPSLER ddPTM_HeLa_Curcumin_4h_R1 2 ATGDGSSPELPSLER 15 0 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 2 0 AT(0.236)GDGS(0.814)S(0.95)PELPSLER;ATGDGS(0.997)S(0.974)PELPS(0.029)LER ; 174.59 0.00025693 39505000 7156.9 6110.7 6443.2 6000 6237.1 7251.4 5201.3 1945.31 6421.2 6483.3 TRUE FALSE FALSE 6590.423813 6638.881679 6681.99066 5975.17359 6162.726656 5747.3779 5347.234479 2538.426064 5716.810425 6708.594192 0.982385225 0.989608477 0.99603441 0.890674472 0.918631606 0.856718671 0.797072282 0.378384203 0.852162206 1 12.71179476 -4.108822077 1.046771708 0.982426826 6.32E-31 0.888651993 0.05873922 0.363723156 0.253499742 0.006390084 0.427537087 7.78E-05 4.108822077 -0.982426826 down T(ph)PTAPAVNLAGAR ddPTM_HeLa_Curcumin_4h_R1 1 TPTAPAVNLAGAR 13 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 T(1)PTAPAVNLAGAR 166.62 0.00052953 36934000 253.26 164.54 173.33 224.94 208.49 221.77 224.26 343.97 170.45 0 TRUE FALSE FALSE 233.2142038 178.7621044 179.7537623 224.0092579 206.0038929 175.7724021 230.552132 448.8448696 151.7520614 0 0 T(ph)PTDPGLDSALEPSGDPHGK ddPTM_HeLa_Curcumin_4h_R1 1 TPTDPGLDSALEPSGDPHGK 20 0 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 0 T(0.794)PT(0.206)DPGLDSALEPSGDPHGK 122.87 9.25E-05 14842000 2936.3 2511.8 2786.3 2528.6 3720.1 3271.9 2583.3 6603.1 2697.3 1993.7 TRUE FALSE FALSE 2703.888757 2728.9088 2889.562729 2518.137323 3675.740237 2593.271058 2655.780445 8616.354793 2401.412938 2062.980927 1.310670749 1.322798851 1.400673507 1.220630443 1.78176162 1.257050429 1.287350945 4.176652669 1.164049995 1 11.01051477 -4.261356221 6.732006526 1.238020475 4.227798851 0.948932264 0.199340759 0.019579142 5.922721166 0.032083777 0.265006677 5.48E-05 4.261356221 2.989778375 T(ph)PTGSPATEVSAK ddPTM_HeLa_Curcumin_4h_R1 1 TPTGSPATEVSAK 13 0 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;S4R3G4;F8WBN2;F6SRV7;Q8NHM5-5 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 0 T(0.669)PT(0.158)GS(0.168)PAT(0.005)EVSAK 104.59 0.015094 4569700 1047.4 909.93 1239.4 1067.3 854.17 890.41 962.86 539.57 904.13 1032.1 TRUE FALSE FALSE 964.4971848 988.5802946 1285.333254 1062.883795 843.9845806 705.728929 989.8752602 704.0824091 804.949201 1067.965398 0.903116511 0.92566697 1.203534549 0.995241791 0.790273339 0.660816287 0.926879524 0.659274552 0.753722173 1 10.06064919 -5.717004515 5.876983983 0.974174744 0.7617838 0.386989895 0.125735146 0.129293831 10.59106413 0.015493315 0.030921063 1.92E-06 5.717004515 -0.212390944 T(ph)PTPEPAEVETR ddPTM_HeLa_Curcumin_4h_R1 2 TPTPEPAEVETR 12 0 F8W6G1;Q9UHY1 F8W6G1 NRBP1 Nuclear receptor-binding protein 1 0 T(0.606)PT(0.394)PEPAEVETR;T(0.999)PT(0.001)PEPAEVETR ; 142.39 0.003056 271570000 2322.35 2402.26 2275.98 1877.26 1706.56 2048 1755.62 1717.02 2140.18 1950.29 TRUE FALSE FALSE 2138.533547 2609.90065 2360.329821 1869.492396 1686.210387 1623.221714 1804.877972 2240.531494 1905.407608 2018.062432 1.059696426 1.293270519 1.169601982 0.926379861 0.835559079 0.804346629 0.894361811 1.110238939 0.94417674 1 10.97875509 -6.101493361 7.319748293 1.062478307 0.89973793 0.348831941 0.118422123 0.264584524 16.80179826 0.01854572 0.030884636 7.92E-07 6.101493361 -0.162740377 T(ph)PTPEPAEVETRK ddPTM_HeLa_Curcumin_4h_R1 1 TPTPEPAEVETRK 13 1 F8W6G1;Q9UHY1 F8W6G1 NRBP1 Nuclear receptor-binding protein 1 0 T(0.799)PT(0.201)PEPAEVETRK 108.72 0.0012193 0 851.72 755.17 841.01 848.19 863.59 1208.6 601.07 673.17 1079.7 801.78 TRUE FALSE FALSE 784.3054633 820.4435298 872.1785704 844.6804145 853.2922533 957.9227363 617.9344065 878.4164341 961.2596113 829.6417953 0.94535433 0.988912968 1.051271254 1.018126641 1.02850683 1.154622081 0.744820729 1.058789997 1.158644148 1 9.696344765 -4.761177304 24.99999999 0.996919902 0.901805445 0.121489275 0.103656771 8.918646725 850277.0596 0.011745285 0.039076086 1.73E-05 4.761177304 -0.095114457 GSWSS(ph)APTSR ddPTM_HeLa_Curcumin_4h_R1 2 GSWSSAPTSR 10 0 Q9H7P9-3;Q9H7P9;H7BXC7 Q9H7P9-3 PLEKHG2 Pleckstrin homology domain-containing family G member 2 1 0 GS(0.007)WS(0.435)S(0.557)APT(0.002)SR;GSWS(0.463)S(0.536)APTSR ; 126.66 0.0034134 94867000 11294 8794.8 8951.1 10515.7 9955.6 11798.9 9313.7 2932.3 11237.3 10052.2 TRUE FALSE FALSE 10400.06798 9554.983323 9282.83564 10472.18882 9836.885972 9351.675139 9575.017355 3826.344771 10004.5963 10401.5132 0.999861057 0.918614738 0.892450498 1.006794744 0.945716818 0.899068718 0.920540807 0.367864242 0.961840466 1 13.34450581 -4.106941657 2.095339859 0.978731233 1.19E-11 0.931849193 0.046737617 0.226996249 0.750825167 0.007226919 0.48344947 7.82E-05 4.106941657 -0.978731233 down T(ph)PVDESDDEIQHDEIPTGK ddPTM_HeLa_Curcumin_4h_R1 1 TPVDESDDEIQHDEIPTGK 19 0 Q86TC9;A0A087WX60;Q86TC9-2 Q86TC9 MYPN Myopalladin 1 0 T(0.5)PVDES(0.5)DDEIQHDEIPTGK 94.671 0.0014102 9608000 3112.8 2646.8 2522.8 2803 2944.3 2909.8 2155 1609.9 3242.5 3250.7 TRUE FALSE FALSE 2866.418595 2875.577598 2616.297187 2791.401929 2909.191145 2306.27468 2215.4635 2100.751099 2886.805862 3363.661583 0.852172112 0.854895038 0.777812251 0.829870027 0.86488818 0.685644088 0.658646373 0.624542941 0.858233146 1 11.71581685 -2.625520002 0.13121414 1.070741462 4.07E-13 0.717529244 0.057870386 13.83611787 0.185520149 0.183990867 2.624476024 0.002368536 2.625520002 -1.070741462 T(ph)PVPSTVQANTFEFADAEEDDEVKV ddPTM_HeLa_Curcumin_4h_R1 1 TPVPSTVQANTFEFADAEEDDEVKV 25 1 Q00587-2;Q00587 Q00587-2 CDC42EP1 Cdc42 effector protein 1 1 0 T(0.932)PVPS(0.056)T(0.012)VQANTFEFADAEEDDEVKV 180.79 4.52E-26 0 1263.7 1067.2 1336.8 1151.7 1240 1084.2 1029.1 1819.3 960.81 928.39 TRUE FALSE FALSE 1163.676812 1159.444013 1386.342984 1146.934571 1225.21381 859.3246985 1057.973776 2373.996195 855.4115468 960.6514834 1.211341295 1.206935119 1.443127927 1.193913287 1.275398863 0.894522846 1.101308638 2.471235652 0.89044941 1 9.907869318 -4.260529277 24.84558991 1.136061011 2.471236109 0.857880029 0.163134415 18.09889176 494008.8884 0.021993617 0.178684747 5.49E-05 4.260529277 1.335175098 T(ph)PVSDDAESTSMFDMR ddPTM_HeLa_Curcumin_4h_R1 2 TPVSDDAESTSMFDMR 16 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 T(1)PVSDDAESTSMFDMR;T(0.997)PVS(0.003)DDAESTSMFDMR ; 139.66 0.0011538 7442200 685.87 614.4 525.72 682.27 538.01 900.54 716.23 406.28 838.66 698.81 TRUE FALSE FALSE 631.5826658 667.5059983 545.2036457 679.4469475 531.5945821 713.7578528 736.3254862 530.1529017 746.6610962 723.0935955 0.873445249 0.923125308 0.753987657 0.939639006 0.735167045 0.987089164 1.018299001 0.733173278 1.032592601 1 9.498038588 -9.107869166 0.722243882 1.006422358 0.873803294 0.256541633 0.097662033 1.007450552 0.887870736 0.078477233 0.019311732 7.80E-10 9.107869166 -0.132619064 T(ph)QLSPSIK ddPTM_HeLa_Curcumin_4h_R1 1 TQLSPSIK 8 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 T(0.825)QLS(0.043)PS(0.132)IK 125.68 0.018844 26338000 4564.1 4273.3 4510.6 4341 5161.1 5319.8 4043.1 3113.4 4107.1 3548.4 TRUE FALSE FALSE 4202.846669 4642.665011 4677.766804 4323.038092 5099.557253 4216.413513 4156.538505 4062.661328 3656.561405 3671.706636 1.144657536 1.264443342 1.274003418 1.17739202 1.388879276 1.148352505 1.132045372 1.106477649 0.995875152 1 11.84223508 -8.293366119 0.856846193 1.018350517 1.212895775 0.509416984 0.080789405 0.332247022 0.516388138 0.030068268 0.018529831 5.09E-09 8.293366119 0.194545258 T(ph)QRLSAETWDLLR ddPTM_HeLa_Curcumin_4h_R1 1 TQRLSAETWDLLR 13 1 A0A0A0MSK4;A0A0A0MRC4;Q86YR5-4;Q86YR5 A0A0A0MSK4 GPSM1 G-protein-signaling modulator 1 1 0 T(0.75)QRLS(0.249)AET(0.001)WDLLR 91.202 0.0094602 3331500 1032.3 823.19 1016.6 1147.5 884.13 1187.3 1260.1 548.92 1107.6 815.96 TRUE FALSE FALSE 950.5923657 894.3428755 1054.27609 1142.751949 873.5873272 941.0405964 1295.455015 716.2831811 986.0990511 844.3145493 1.125874671 1.059253185 1.248676919 1.353467082 1.034670465 1.114561625 1.53432748 0.84836058 1.167928531 1 9.721636765 -8.149575375 0.542133753 1.00400172 1.195241469 0.005233294 0.182825093 1.150756358 0.771543053 0.093785366 0.051235317 7.09E-09 8.149575375 0.191239749 T(ph)QSAPLPQNAQALQHLVIQQQHQQFLEK ddPTM_HeLa_Curcumin_4h_R1 1 TQSAPLPQNAQALQHLVIQQQHQQFLEK 28 0 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 0 T(0.5)QS(0.5)APLPQNAQALQHLVIQQQHQQFLEK 105.52 1.44E-09 29925000 1501.6 895.43 964.28 1215.8 1307.9 1074.8 1067.6 1021.2 1193.4 1267.9 TRUE FALSE FALSE 1382.746776 972.8269792 1000.017065 1210.769342 1292.304147 851.8743645 1097.553983 1332.559179 1062.487006 1311.959431 1.053955437 0.741506907 0.762231698 0.922871023 0.985018375 0.649314563 0.83657616 1.015701513 0.809847455 1 10.35750739 -7.276009896 24.8001922 1.025478961 0.842141251 0.060514155 0.125990988 525.6840179 894754.4268 0.017986592 0.02061538 5.30E-08 7.276009896 -0.183337711 (ac)S(ph)SGIHVALVTGGNK ddPTM_HeLa_Curcumin_4h_R1 1 SSGIHVALVTGGNK 14 0 P16152;E9PQ63;A8MTM1;P16152-2 P16152 CBR1 Carbonyl reductase [NADPH] 1 1 0 S(0.5)S(0.5)GIHVALVTGGNK 72.096 0.0023039 4360300 2172.7 1865.1 1873.2 1652.7 2078.6 3245.1 2330.3 3989.7 2426.8 1810 TRUE FALSE FALSE 2000.728502 2026.310933 1942.62244 1645.861565 2053.814053 2572.02968 2395.681946 5206.141164 2160.586112 1872.897365 1.068253146 1.081912427 1.037228455 0.878778301 1.096597225 1.373289176 1.279131463 2.77972582 1.153606253 1 10.87105613 -2.094906437 1.077336657 1.032854781 199.9999998 0.948060724 0.118193459 24.12890887 0.312296178 0.015929974 11548.6635 0.008036992 2.094906437 198.967145 up T(ph)QSSLTVSEVLTRR ddPTM_HeLa_Curcumin_4h_R1 1 TQSSLTVSEVLTRR 14 1 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 T(0.641)QS(0.192)S(0.121)LT(0.045)VS(0.002)EVLTRR 71.143 0.016412 9899800 2058 1562.1 1926.7 1637.7 2342 2533.2 1642.6 1680.5 1981.5 1973.4 TRUE FALSE FALSE 1895.107128 1697.120963 1998.105197 1630.923631 2314.07318 2007.785765 1688.686935 2192.876714 1764.134407 2041.975503 0.928075349 0.8311172 0.978515753 0.798698921 1.133252175 0.983256539 0.826986873 1.073899619 0.863935147 1 10.99574984 -3.873145491 15.13238153 0.951395784 11.25521479 0.124923169 0.099317053 1110355.799 598998.2382 0.012478943 392121321.6 0.000133923 3.873145491 10.303819 SYLLGNSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 SYLLGNSSPR 10 0 P02545;P02545-3;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 1 0 SYLLGNS(0.026)S(0.974)PR;SYLLGNS(0.001)S(0.999)PR ; 163.12 0.00059689 123955000 9966.2 7147.7 8862.4 8264.5 8499.1 15369.2 12879.4 22675 8895.1 7300.7 TRUE FALSE FALSE 9177.364754 7765.515338 9190.84834 8230.303689 8397.753783 12181.45467 13240.7613 29588.50312 7919.329784 7554.398782 1.214837212 1.027946176 1.216622078 1.089471701 1.111637607 1.612498231 1.752722048 3.916725073 1.048307087 1 12.88310123 -2.057784231 0.94781219 1.102541479 199.9999995 0.977710907 0.125576065 11.91815165 0.191769683 0.019682293 4941.424877 0.008754186 2.057784231 198.897458 up RNALFPEVFS(ph)PTPDENSDQNSR ddPTM_HeLa_Curcumin_4h_R1 1 RNALFPEVFSPTPDENSDQNSR 22 1 Q8IVT2 Q8IVT2 MISP Mitotic interactor and substrate of PLK1 1 0 RNALFPEVFS(0.912)PT(0.088)PDENSDQNSR 114.53 4.81E-06 3326600 569.06 451.79 458.02 614.61 442.9 650.22 494.08 659.34 571.88 351.75 TRUE FALSE FALSE 524.0183005 490.8407145 474.9946241 612.0669067 437.6187068 515.3570425 507.9425551 860.3697308 509.1461948 363.9732863 1.439716375 1.348562471 1.305026061 1.681625904 1.202337433 1.415919964 1.395548998 2.363826586 1.398855943 1 8.507688758 -2.031286734 1.14503039 1.264329705 199.9976816 0.722527567 0.181746785 122.6379545 1.13637761 0.0328713 62934.87588 0.009304933 2.031286734 198.7333519 up LPLS(ph)PPLVEDSAFEPSRK ddPTM_HeLa_Curcumin_4h_R1 3 LPLSPPLVEDSAFEPSRK 18 1 O96007 O96007 MOCS2 Molybdopterin synthase catalytic subunit 1 0 LPLS(1)PPLVEDSAFEPSRK;LPLS(1)PPLVEDSAFEPSRK;LPLS(1)PPLVEDSAFEPSRK ;; 128.74 9.98E-05 299162000 7268.1 6496.7 7054.2 6980.1 7845.1 10558.8 7714.3 11597.5 7094.9 6912.6 TRUE FALSE FALSE 6692.822216 7058.245799 7315.634858 6951.218196 7751.552306 8368.785858 7930.742496 15133.52436 6316.607221 7152.812335 0.935691012 0.986779111 1.022763427 0.971816101 1.083706931 1.16999936 1.108758643 2.11574464 0.883094219 1 12.80429488 -2.008358915 1.126293693 0.982858405 200 0.948885378 0.076619026 36.99616922 0.340269382 0.01038923 18693.03282 0.009809369 2.008358915 199.0171416 up T(ph)QTPPVSPAPQPTEER ddPTM_HeLa_Curcumin_4h_R1 2 TQTPPVSPAPQPTEER 16 0 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 1 0 T(0.814)QT(0.186)PPVSPAPQPTEER;T(0.913)QT(0.086)PPVSPAPQPTEER ; 168.68 0.00043926 362170000 2726.6 2963.3 3059.7 2925.6 3066 2993.3 2827.6 1615.53 3077.1 2378.8 TRUE FALSE FALSE 2510.786733 3219.434448 3173.095174 2913.494642 3029.439952 2372.455839 2906.934846 2108.09766 2739.549829 2461.463123 1.02003833 1.307935275 1.289109369 1.183643425 1.230747649 0.963839684 1.180978427 0.856440887 1.112976182 1 11.26530041 -7.47945938 24.55816833 1.008840359 1.150513474 0.085398387 0.135905073 418.9597917 236967.1071 0.022217049 0.025222738 3.32E-08 7.47945938 0.141673115 T(ph)RAET(ph)MGPMGCLFNMK ddPTM_HeLa_Curcumin_4h_R1 1 TRAETMGPMGCLFNMK 16 1 A0A1B0GUZ5 A0A1B0GUZ5 2 0 T(1)RAET(1)MGPMGCLFNMK 42.716 0.018951 3356800 853.27 833.26 800.78 852.24 785.29 839.09 852.21 834.65 964.65 1021.8 TRUE FALSE FALSE 785.7327791 905.2832815 830.4576112 848.7136567 775.9259296 665.0532755 876.120719 1089.130943 858.8303084 1057.307474 0.743145016 0.856215721 0.785445702 0.802712246 0.73386971 0.629006502 0.828633809 1.030098594 0.812280561 1 10.04617927 -9.367657786 0.934422079 1.008504943 0.791451482 0.015154955 0.112818086 0.528323633 0.772409899 0.082072869 0.018195199 4.29E-10 9.367657786 -0.217053461 T(ph)RIS(ph)QFNMHVDS(ph)RR ddPTM_HeLa_Curcumin_4h_R1 1 TRISQFNMHVDSRR 14 2 A0A0C4DFS5;H0YJJ2;Q8NDG6-2;Q8NDG6 A0A0C4DFS5 TDRD9 Putative ATP-dependent RNA helicase TDRD9 3 0 T(1)RIS(1)QFNMHVDS(1)RR 80.387 0.018833 5948300 428.74 305.91 322.77 364.89 436.21 140.76 176.17 125.14 490.01 274.1 TRUE FALSE FALSE 394.8047766 332.3514973 334.7321401 363.3801819 431.0084806 111.5647893 181.1128561 163.2946099 436.2571289 283.6249546 1.391995909 1.171799208 1.180192838 1.281199612 1.519642308 0.393353221 0.638564601 0.575741335 1.538147902 1 8.147840663 -5.253369991 24.99948583 1.214377307 0.546154175 0.787430456 0.177687984 231.378882 716824.656 0.025639334 0.064113229 5.58E-06 5.253369991 -0.668223132 T(ph)RLSTASEETVQNR ddPTM_HeLa_Curcumin_4h_R1 2 TRLSTASEETVQNR 14 1 O43379;O43379-4;H7C3R4;O43379-3;O43379-2 O43379 WDR62 WD repeat-containing protein 62 1 0 T(0.664)RLS(0.164)T(0.164)AS(0.006)EET(0.002)VQNR;T(0.386)RLS(0.226)T(0.386)AS(0.001)EETVQNR ; 156.2 0.0036255 24412300 1594.5 1452.14 1591.17 1680.1 1515.79 1963.69 1508.72 1326.17 1996.21 1770.06 TRUE FALSE FALSE 1468.293642 1577.656511 1650.14016 1673.148191 1497.715194 1556.398559 1551.050623 1730.513128 1777.230757 1831.569453 0.80165873 0.861368652 0.900943263 0.913505185 0.817722305 0.849762239 0.846842373 0.944825284 0.970332167 1 10.83886469 -9.479702068 1.206415526 1.000397183 0.859891108 0.548756195 0.04224862 0.267908306 0.694508862 0.031272258 0.007571671 3.31E-10 9.479702068 -0.140506075 T(ph)RNSGIWESPELDR ddPTM_HeLa_Curcumin_4h_R1 1 TRNSGIWESPELDR 14 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 0 T(0.985)RNS(0.015)GIWESPELDR 117.53 0.0016337 9668200 860.09 865.23 841.3 929.39 1170.1 1003.3 779.39 711.26 1026.5 856.96 TRUE FALSE FALSE 792.0129689 940.0166258 872.4793181 925.5444304 1156.147322 795.2042705 801.2575858 928.1198998 913.8955182 886.7392962 0.893174547 1.060082292 0.983918635 1.043761604 1.303818751 0.896773464 0.903599952 1.046666031 1.030624809 1 9.7923662 -7.248550192 24.47057246 0.949554646 1.032605177 0.042597356 0.111531509 1037.851299 1970397.996 0.018865925 0.023018248 5.64E-08 7.248550192 0.083050531 T(ph)RS(ph)RS(ph)PESQVIGENTKQP ddPTM_HeLa_Curcumin_4h_R1 1 TRSRSPESQVIGENTKQP 18 3 O95218-2 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 3 0 T(1)RS(1)RS(1)PESQVIGENTKQP 85.636 0.0051411 23836000 3626.5 3148.1 3303.4 3108.8 3184.8 3895 3036.3 1982.6 4340.2 3648.3 TRUE FALSE FALSE 3339.458698 3420.207736 3425.82691 3095.936609 3146.82334 3087.133094 3121.490406 2587.085613 3864.090919 3775.078153 0.884606507 0.905996538 0.90748503 0.82009868 0.833578329 0.817766671 0.826867757 0.685306504 1.023579052 1 11.8822908 -1 0.097255665 1.091955935 0.095137734 0.861167416 0.034536657 34.43922563 0.239939895 0.298247912 4.599941612 0.1 1 -0.996818202 T(ph)RS(ph)VEDDEEGHLICQSGDVLSAR ddPTM_HeLa_Curcumin_4h_R1 1 TRSVEDDEEGHLICQSGDVLSAR 23 1 F8WBF5;P49759;P49759-3 F8WBF5 CLK1 Dual specificity protein kinase CLK1 2 0 T(1)RS(1)VEDDEEGHLICQSGDVLSAR 71.903 0.002295 10561000 1103.2 827.96 972.11 830.15 1011.3 1690.4 1338.5 569.7 1120.5 929.74 TRUE FALSE FALSE 1015.880556 899.5251731 1008.137252 826.7150593 999.240908 1339.791985 1376.054708 743.3989074 997.5839534 962.0483958 1.055955771 0.935010314 1.047907004 0.859327933 1.03865971 1.392645101 1.430338342 0.772725063 1.036937391 1 9.90996566 -5.448342628 10.56501073 1.00830999 1.221115387 0.215748143 0.175084945 0.685479014 94.94175138 0.023077003 0.051612809 3.56E-06 5.448342628 0.212805397 T(ph)RSEPLPPSATAPPPPGPMQPR ddPTM_HeLa_Curcumin_4h_R1 1 TRSEPLPPSATAPPPPGPMQPR 22 1 J3KPH8;Q8WUI4-3;Q8WUI4-4;Q8WUI4;Q8WUI4-7;Q8WUI4-6;Q8WUI4-5;Q8WUI4-8;Q8WUI4-10 J3KPH8 HDAC7 Histone deacetylase;Histone deacetylase 7 1 0 T(0.552)RS(0.429)EPLPPS(0.017)AT(0.002)APPPPGPMQPR 54.3 0.0089929 29428000 1017.8 713.75 718.85 718.81 852.2 863.51 691.6 432.45 795.9 861.3 TRUE FALSE FALSE 937.240056 775.4433696 745.4912134 715.8357547 842.0380716 684.4082922 711.0044347 564.3020142 708.5917612 891.2301109 1.051625214 0.870082104 0.836474446 0.803199697 0.944804334 0.76793668 0.79777874 0.63317207 0.795071612 1 9.799654166 -5.221590386 0.348369624 1.037380481 0.572559218 0.252569455 0.100230809 1.443120328 0.199445384 0.029871647 0.259098838 6.00E-06 5.221590386 -0.464821263 T(ph)RSLSSLR ddPTM_HeLa_Curcumin_4h_R1 1 TRSLSSLR 8 1 O94915;H0Y9X0;A0A286YEZ9;A0A2C9F2R7 O94915 FRYL Protein furry homolog-like 1 0 T(0.988)RS(0.007)LS(0.002)S(0.002)LR 104.05 0.010672 11209000 1889.6 1071 1484.7 1462.1 1345.8 2124.1 1765.2 1267.2 1851.6 1806.8 TRUE FALSE FALSE 1740.036166 1163.572468 1539.724288 1456.050218 1329.752214 1683.537716 1814.726761 1653.563447 1648.484112 1869.586166 0.930706591 0.622368998 0.823564229 0.778808832 0.711254843 0.900486828 0.970656926 0.884454259 0.881737436 1 10.86850325 -7.492070679 15.39470473 0.969439425 0.814735825 0.247018893 0.097073627 3.673985449 1836.260406 0.017152922 0.018894669 3.22E-08 7.492070679 -0.1547036 T(ph)RSNPEGAEDR ddPTM_HeLa_Curcumin_4h_R1 2 TRSNPEGAEDR 11 1 M0QXG9;M0R3F4;M0R2A4;M0R2K3;M0R193;M0R0I0;J3KQS6;Q9NWV8-3;Q9NWV8;M0R3H9;M0R2I2 M0QXG9 BABAM1 BRISC and BRCA1-A complex member 1 1 0 T(0.851)RS(0.149)NPEGAEDR;T(0.932)RS(0.068)NPEGAEDR ; 112.85 0.004638 429320000 7276.4 6141.4 6022.2 6589.8 6356.4 7754.3 5800.5 3184.3 6951.2 6046.1 TRUE FALSE FALSE 6700.465262 6672.23525 6245.38803 6562.533154 6280.604082 6145.970771 5963.246419 4155.178411 6188.670751 6256.201525 1.071011737 1.066499412 0.998271556 1.048964476 1.003900539 0.982380562 0.953173646 0.664169528 0.989205787 1 12.61107127 -3.788277783 1.227546056 1.03326164 7.05E-18 0.925330314 0.030223711 0.783275008 0.445177503 0.004845769 1.362731265 0.000162825 3.788277783 -1.03326164 T(ph)RSYDNLTTACDNTVPLASR ddPTM_HeLa_Curcumin_4h_R1 1 TRSYDNLTTACDNTVPLASR 20 1 Q13615-3;Q13615-2;Q13615;G5E953 Q13615-3 MTMR3 Myotubularin-related protein 3 1 0 T(0.532)RS(0.386)Y(0.082)DNLTTACDNTVPLASR 97.94 0.00055484 20062000 883.06 557.75 710.27 699.42 545.99 838.49 553.2 379.44 784.07 601.09 TRUE FALSE FALSE 813.1648692 605.9594247 736.593231 696.5259854 539.4794258 664.5777223 568.7213031 495.1295093 698.0594826 621.9778328 1.307385611 0.974246015 1.184275696 1.119856607 0.867361178 1.068491009 0.914375518 0.79605652 1.122322124 1 9.280719354 -4.864186312 0.672434572 1.1381435 0.754310987 0.44582075 0.109683374 1.358220158 0.664732476 0.024653169 0.340089522 1.37E-05 4.864186312 -0.383832514 T(ph)RT(ph)FSAT(ph)VRASQGPVY(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 TRTFSATVRASQGPVYK 17 2 H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9;Q9Y2V2 H3BTK3 CARHSP1 Calcium-regulated heat stable protein 1 4 0 T(0.956)RT(0.982)FS(0.361)AT(0.703)VRAS(0.211)QGPVY(0.788)K 50.189 0.019171 27580000 2909.7 2859.7 2509.8 2565.7 2797.6 3119.6 2438.9 2366.9 2217.4 2238.8 TRUE FALSE FALSE 2679.394175 3106.879725 2602.815396 2555.083813 2764.240447 2472.559795 2507.32897 3088.556914 1974.156768 2316.598133 1.156607241 1.341138837 1.123550675 1.102946504 1.193232614 1.067323572 1.082332293 1.333229475 0.85217921 1 11.17779208 -8.892359174 0.902583654 1.006748827 1.167925493 0.434600224 0.104033442 0.489713044 0.771162451 0.046314646 0.0178062 1.28E-09 8.892359174 0.161176666 T(ph)RT(ph)LRDQEDEIFK ddPTM_HeLa_Curcumin_4h_R1 1 TRTLRDQEDEIFK 13 2 Q96S90;Q96S90-2 Q96S90 LYSMD1 LysM and putative peptidoglycan-binding domain-containing protein 1 2 0 T(1)RT(1)LRDQEDEIFK 90.793 0.013621 5062500 1844.8 1533.9 1622.8 1732.2 1677.9 1992.8 1481.7 1637.1 2205.9 1564.1 TRUE FALSE FALSE 1698.782133 1666.483481 1682.942396 1725.032615 1657.892138 1579.470817 1523.272514 2136.244254 1963.918289 1618.452359 1.049633698 1.029677193 1.039846732 1.065853194 1.024368823 0.97591431 0.941190827 1.319930267 1.213454495 1 10.66039918 -4.25192699 24.98132969 1.020993667 1.319930426 0.584385747 0.07011235 355.4464124 933450.2448 0.005197893 0.089979689 5.60E-05 4.25192699 0.298936759 T(ph)RT(ph)PASINATPANINLADLTR ddPTM_HeLa_Curcumin_4h_R1 1 TRTPASINATPANINLADLTR 21 1 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 2 0 T(0.853)RT(0.649)PAS(0.497)INAT(0.002)PANINLADLTR 68.361 0.0022092 3966600 512.3 646.06 606.65 648.55 766.69 621.73 468.3 257.06 750.45 620.43 TRUE FALSE FALSE 471.7509144 701.9025476 629.1329827 645.8664719 757.5477225 492.7761897 481.4392376 335.4364106 668.1275125 641.9898963 0.734826073 1.093323355 0.97997334 1.006038375 1.179999447 0.767576238 0.749917157 0.522494844 1.040713439 1 9.326406782 -4.5400551 1.828861894 0.923505624 0.510620949 0.526248927 0.13284408 0.400110696 1.995860001 0.022115756 0.233691438 2.88E-05 4.5400551 -0.412884675 T(ph)RTPAS(ph)INATPANINLADLTR ddPTM_HeLa_Curcumin_4h_R1 1 TRTPASINATPANINLADLTR 21 1 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 2 0 T(0.504)RT(0.504)PAS(0.871)INAT(0.12)PANINLADLTR 62.696 0.01322 5656400 1073.3 891.69 859.97 1002.8 1022.4 1381.4 634.82 469.97 1309.7 1093.7 TRUE FALSE FALSE 988.3471725 968.7637103 891.8412447 998.6506793 1010.208548 1094.882068 652.6313407 613.2616895 1166.029187 1131.705994 0.873325031 0.856020659 0.788050297 0.882429434 0.892642218 0.96746158 0.57667923 0.541891351 1.030328719 1 10.14428349 -4.754577493 24.72231475 0.916050106 0.559285028 0.808717229 0.068444597 44.44425657 160120.5933 0.010381671 0.037147084 1.76E-05 4.754577493 -0.356765078 T(ph)S(ph)ALPGET(ph)QRRL ddPTM_HeLa_Curcumin_4h_R1 1 TSALPGETQRRL 12 2 J3QLL8;Q8N584-3 J3QLL8 TTC39C Tetratricopeptide repeat protein 39C 3 0 T(1)S(1)ALPGET(1)QRRL 63.864 0.02028 25464000 275.32 348.28 333.39 512.33 343.91 315.44 289.17 316.76 377.65 296.01 TRUE FALSE FALSE 253.5281315 378.3837713 345.7457267 510.2101142 339.8090979 250.0141883 297.2833319 413.3386658 336.2227398 306.2963255 0.827721753 1.235351977 1.128794889 1.665740238 1.10941291 0.816249388 0.970574268 1.349473146 1.097704125 1 8.258784249 -7.257398817 24.81817847 0.918646383 1.173752393 0.138157569 0.22336567 366.8481458 2253279.245 0.038253251 0.04594694 5.53E-08 7.257398817 0.255106011 T(ph)S(ph)AMLTVRAMPSK ddPTM_HeLa_Curcumin_4h_R1 1 TSAMLTVRAMPSK 13 1 H3BQA7;A6NGQ3;Q5VST9-5;Q5VST9-3;Q5VST9;Q5VST9-2;Q5VST9-6 H3BQA7 OBSCN Obscurin 2 0 T(1)S(1)AMLTVRAMPSK 68.171 0.011679 14939000 2470.3 2433.7 2524 2368.5 2820.5 4074.6 2926.8 1935.8 2410.1 2221.9 TRUE FALSE FALSE 2274.773148 2644.058184 2617.54166 2358.699775 2786.86738 3229.48203 3008.918131 2526.016509 2145.71806 2299.11086 0.989414294 1.150035098 1.138501717 1.025918243 1.212150066 1.404665641 1.308731207 1.098692783 0.933281686 1 11.16686032 -6.267339635 0.740739105 0.994392259 1.275634183 0.548635598 0.095399589 0.358773855 0.385596904 0.019443998 0.047447869 5.40E-07 6.267339635 0.281241924 T(ph)S(ph)LPAPMFS(ph)RSDFS(ph)VWT(ph)ILK ddPTM_HeLa_Curcumin_4h_R1 1 TSLPAPMFSRSDFSVWTILK 20 1 A0A2R8Y429;A0A2R8Y703;A0A2R8YG53;A0A087WTV1;A0A2R8YG95;A0A2R8YFT0;A0A2R8Y690;A0A2R8YG59;A0A2R8Y5R1;A0A2R8Y362;A0A2R8YD49;Q9H1P3-2;Q9H1P3 A0A2R8Y429 OSBPL2 Oxysterol-binding protein-related protein 2 5 0 T(1)S(1)LPAPMFS(0.502)RS(0.502)DFS(0.997)VWT(0.999)ILK 48.907 0.0087042 0 1035.2 918.38 875.06 767.18 882.41 1305.6 1090.6 835.52 1132.6 1043.6 TRUE FALSE FALSE 953.2628277 997.760675 907.4904934 764.0056124 871.8878371 1034.803843 1121.199301 1090.266202 1008.356614 1079.865022 0.882761093 0.923967954 0.840374005 0.707501027 0.807404462 0.95827147 1.038277264 1.009631925 0.933780234 1 10.07663528 -4.971496203 5.810539731 0.906786516 1.019833791 0.315768872 0.080493561 0.229429466 22.96061102 0.01405488 0.04234064 1.07E-05 4.971496203 0.113047275 T(ph)S(ph)REDMFS(ph)EKQDIPFVEQEDPY(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 TSREDMFSEKQDIPFVEQEDPYR 23 2 H0Y2M0;A2VDJ0-2;A2VDJ0-6;A2VDJ0-3;A2VDJ0;A2VDJ0-5 H0Y2M0 KIAA0922 Transmembrane protein 131-like 4 0 T(1)S(1)REDMFS(1)EKQDIPFVEQEDPY(1)R 42.355 0.0084529 0 694.15 802.73 697.43 602.59 543.89 652.6 654.89 701.52 751.82 730.3 TRUE FALSE FALSE 639.207295 872.1144043 723.2773693 600.0966422 537.404467 517.2434037 673.2644509 915.4102186 669.347227 755.6778706 0.845872719 1.154082233 0.957123925 0.794116998 0.711155491 0.68447605 0.89094107 1.211376241 0.885757348 1 9.561627565 -6.275949362 23.2944806 0.948032044 0.842376121 0.099966204 0.155741631 633.817937 1017537.171 0.024946674 0.038237644 5.30E-07 6.275949362 -0.105655922 T(ph)S(ph)RT(ph)KRR ddPTM_HeLa_Curcumin_4h_R1 2 TSRTKRR 7 3 J3KN16 J3KN16 KIAA0368 3 0 T(1)S(1)RT(1)KRR;T(1)S(1)RT(1)KRR ; 73.985 0.018253 378180000 8476.5 6586.2 6816.9 7151.4 6702.3 8180.5 6841.6 6683.3 8610.6 7219.6 TRUE FALSE FALSE 7805.576081 7155.48178 7069.540311 7121.809402 6622.37945 6483.772087 7033.556883 8721.007404 7666.038723 7470.480563 1.044855952 0.957834201 0.946330059 0.95332681 0.886473018 0.867919009 0.94151331 1.167395769 1.026177454 1 12.86698534 -7.203506752 7.409640738 1.021156249 0.952042822 0.119678762 0.076785822 0.404027328 45.89613532 0.012707861 0.015557336 6.26E-08 7.203506752 -0.069113427 T(ph)S(ph)S(ph)KT(ph)PS(ph)SPSK ddPTM_HeLa_Curcumin_4h_R1 1 TSSKTPSSPSK 11 1 H0Y911;Q4VXL4;D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-2;O95359-6;O95359-1;O95359-5;O95359-3;O95359;E9PGB3;H0YA73 H0Y911 TACC2 Transforming acidic coiled-coil-containing protein 2 5 0 T(0.98)S(0.98)S(0.98)KT(0.95)PS(0.946)S(0.142)PS(0.023)K 41.029 0.018371 20204000 2456.7 1773.8 2085.6 2199 2322.5 3022.6 2114.6 1937.8 2687.3 2332.4 TRUE FALSE FALSE 2262.249603 1927.119368 2162.894171 2189.901121 2294.805704 2395.678688 2173.929985 2528.626299 2392.509913 2413.450726 0.937350648 0.798491283 0.896183273 0.907373454 0.950840089 0.992636254 0.900755902 1.047722364 0.99132329 1 11.23688166 -3.134678146 16.71741376 0.950009372 0.941455579 0 0.06769817 0 0 0.009285599 0 0.000733368 3.134678146 -0.008553793 SEAEEGEVRT(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 1 SEAEEGEVRTPTK 13 1 A0A1B0GTW6;A0A0C4DH22;Q9H4G0;Q9H4G0-4;H7C2K6;Q9H4G0-3;Q9H4G0-2 A0A1B0GTW6;Q9H4G0-3 EPB41L1 Band 4.1-like protein 1 1 0 SEAEEGEVRT(0.999)PT(0.001)K 86.539 0.012929 399430000 3259.1 2347.8 2902.8 2667.2 3408.7 3535.3 3177.6 4403.7 2717.5 2241.5 TRUE FALSE FALSE 3001.138796 2550.73337 3010.380322 2656.163833 3368.053479 2802.038929 3266.754904 5746.367858 2419.397049 2319.391958 1.293933432 1.099742267 1.297917892 1.145198346 1.452127773 1.208092026 1.408453148 2.477532026 1.043116943 1 11.17953093 -1.972408504 1.072491887 1.164393235 200 0.898226451 0.12887262 57.98811927 0.565620642 0.02196263 27790.04326 0.010655933 1.972408504 198.8356068 up T(ph)SDIFGSPVTATSR ddPTM_HeLa_Curcumin_4h_R1 1 TSDIFGSPVTATSR 14 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2;H3BMV3;H3BMT0;H3BTV5 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 0 T(0.978)S(0.009)DIFGS(0.013)PVTATSR 182.37 0.00028234 705990000 4120.3 3184.7 3182.5 3392.9 3233.9 4765.6 3593.7 1598.1 3965.9 2555.2 TRUE FALSE FALSE 3794.173907 3459.971277 3300.44625 3378.861079 3195.337855 3777.160841 3694.52955 2085.353333 3530.850692 2643.99301 1.435016618 1.308615894 1.248281004 1.277938734 1.208527346 1.428582007 1.397329545 0.788713633 1.335423611 1 11.36850265 -9.529778602 1.299584857 1.000601165 1.291134843 0 0.203885248 0.463951357 1.407761201 0.117902676 0.028437831 2.95E-10 9.529778602 0.290533679 T(ph)SDPNPAAPDSESVIVAMER ddPTM_HeLa_Curcumin_4h_R1 1 TSDPNPAAPDSESVIVAMER 20 0 P42858 P42858 HTT Huntingtin 1 0 T(0.572)S(0.428)DPNPAAPDSESVIVAMER 150.69 1.26E-09 0 698.99 631.06 760.11 535.13 721.01 754.77 336.37 329.09 653.63 688.42 TRUE FALSE FALSE 643.6642039 685.6060145 788.2803453 532.9157739 712.4124267 598.222194 345.8076369 429.4280261 581.9284243 712.3425438 0.903588041 0.962466752 1.106602929 0.748117291 1.000098103 0.839795684 0.485451332 0.602839224 0.816922181 1 9.476427346 -4.887725732 4.070376732 0.951785916 0.545116007 0.700274339 0.09973028 0.0701744 2.100706646 0.012101365 0.040086191 1.30E-05 4.887725732 -0.406669909 SSSLPAS(ph)QNNLRH ddPTM_HeLa_Curcumin_4h_R1 1 SSSLPASQNNLRH 13 1 H3BU49;Q9Y2Y0-2;Q9Y2Y0 H3BU49 ARL2BP ADP-ribosylation factor-like protein 2-binding protein 1 0 SSSLPAS(1)QNNLRH 68.751 0.01758 2072700 1980.2 1841.9 1971.2 2184.8 2080.3 3002.8 2242.5 3337.3 2488.8 2006.9 TRUE FALSE FALSE 1823.465081 2001.105629 2044.254406 2175.759876 2055.493781 2379.985431 2305.418515 4354.827407 2215.784867 2076.639626 0.878084506 0.963626815 0.984404988 1.047731079 0.989817278 1.146075324 1.110167834 2.09705495 1.067005001 1 11.02003516 -1.950386153 1.092838035 0.957228708 200 0.944519761 0.077958797 40.13768889 0.350614948 0.011370173 19677.70037 0.011210213 1.950386153 199.0427713 up T(ph)SDVGGYYYEK ddPTM_HeLa_Curcumin_4h_R1 1 TSDVGGYYYEK 11 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(0.999)S(0.001)DVGGYYYEK 201.38 1.07E-06 83425000 2086 2146.6 2080.4 1893.1 2262.8 3100.1 2273.3 1420.8 2530 1990.1 TRUE FALSE FALSE 1920.890899 2332.142539 2157.501454 1885.266854 2235.817588 2457.104315 2337.08268 1853.995379 2252.46533 2059.255827 0.932808286 1.132517149 1.047709287 0.915508811 1.085740566 1.193200127 1.134916143 0.900322998 1.093824915 1 11.00790736 -7.27545494 24.56997502 0.968270579 1.061800779 0.001732665 0.096896221 779.3475181 1366231.767 0.015428846 0.017687561 5.30E-08 7.27545494 0.093530199 T(ph)SETSISPPGSSIGS(ph)PNR ddPTM_HeLa_Curcumin_4h_R1 1 TSETSISPPGSSIGSPNR 18 0 A0A0C4DGA7;O94929-2;O94929-3;O94929 A0A0C4DGA7 ABLIM3 Actin-binding LIM protein 3 2 0 T(0.871)S(0.081)ET(0.029)S(0.01)IS(0.007)PPGS(0.248)S(0.052)IGS(0.702)PNR 91.926 0.011169 11026000 1775.9 1696.8 1561.8 1636.8 2008.3 1664.9 1238.9 755.55 1771.5 1716.5 TRUE FALSE FALSE 1635.335641 1843.463831 1619.681682 1630.027355 1984.352334 1319.580973 1273.6602 985.9137169 1577.170882 1776.148247 0.92072024 1.037899755 0.91190681 0.91773159 1.117222246 0.742945289 0.717091156 0.555085263 0.887972547 1 10.79453629 -5.059381206 4.221982372 0.969048758 0.6508936 0.771247856 0.075721873 0.068413493 2.451125126 0.009818748 0.027640305 8.72E-06 5.059381206 -0.318155158 LSSGLVS(ph)PAPSFYSK ddPTM_HeLa_Curcumin_4h_R1 2 LSSGLVSPAPSFYSK 15 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 0 LSS(0.1)GLVS(0.9)PAPSFYSK;LSS(0.008)GLVS(0.979)PAPS(0.012)FYS(0.001)K ; 193.77 1.81E-06 81069000 7668.3 4505.8 5801.4 6053.4 5980.8 6327.1 4475.2 1974.22 7000.4 5768.2 TRUE FALSE FALSE 7061.345963 4895.261275 6016.404987 6028.352635 5909.482866 5014.788139 4600.762068 2576.15059 6232.473634 5968.644521 1.183073634 0.82016298 1.008001895 1.01000363 0.990087925 0.840188777 0.770821926 0.431614009 1.044202517 1 12.54318762 -4.105335857 0.698233536 1.06319041 1.65E-14 0.783922169 0.09154743 1.233460739 0.361987489 0.017934605 1.085746823 7.85E-05 4.105335857 -1.06319041 down T(ph)SMLRSLLCSCSWR ddPTM_HeLa_Curcumin_4h_R1 1 TSMLRSLLCSCSWR 14 1 Q7L591-2;Q7L591-4;Q7L591-3 Q7L591-2 1 0 T(0.5)S(0.5)MLRSLLCSCSWR 83.204 0.0090631 68214000 4525.1 3389.5 3852.5 3923.9 3203.6 4247 3967 4094.4 3930.6 3637.3 TRUE FALSE FALSE 4166.93356 3682.473277 3995.277039 3907.663941 3165.399162 3366.124326 4078.303343 5342.763712 3499.423014 3763.695904 1.107138745 0.97841945 1.061530246 1.038251772 0.841034781 0.894366711 1.083590026 1.419552442 0.929783676 1 11.87793435 -4.282374933 3.937854783 1.022147518 1.448929845 0.69617677 0.083422087 0.106035234 3.302294703 0.012396843 0.124536671 5.22E-05 4.282374933 0.426782326 T(ph)SPAKQQAPPVR ddPTM_HeLa_Curcumin_4h_R1 2 TSPAKQQAPPVR 12 1 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 0 T(0.945)S(0.055)PAKQQAPPVR;T(0.953)S(0.047)PAKQQAPPVR ; 86.803 0.014889 235882000 10552.3 8591.5 6515.7 7914.1 5345.8 9351.7 6484 6179.1 12571.1 10403.3 TRUE FALSE FALSE 9717.07432 9334.110977 6757.177574 7881.353551 5282.054826 7412.052005 6665.923589 8063.079145 11192.08178 10764.8139 0.902669977 0.867094505 0.627709651 0.732140251 0.490677765 0.68854437 0.61923259 0.749021694 1.039691153 1 13.39403576 -6.966814063 1.412027504 0.961708883 0.640455761 0.785640906 0.077768499 0.121736458 0.478100159 0.01326219 0.017846024 1.08E-07 6.966814063 -0.321253122 YQQETSVSQLPGRPKS(ph)PLSK ddPTM_HeLa_Curcumin_4h_R1 3 YQQETSVSQLPGRPKSPLSK 20 2 Q9HCD6;Q9HCD6-2 Q9HCD6 TANC2 Protein TANC2 1 0 YQQET(0.001)S(0.001)VS(0.001)QLPGRPKS(0.943)PLS(0.055)K;YQQETSVSQLPGRPKS(0.771)PLS(0.229)K;YQQETSVSQLPGRPKS(0.856)PLS(0.144)K ;; 94.313 0.00025798 322452000 12652.5 11314.7 12092.8 11682.8 12088.3 12904.8 8704.8 4074.52 13397.4 12388.8 TRUE FALSE FALSE 11651.04127 12292.69225 12540.96981 11634.45967 11944.15492 10228.19901 8949.03326 5316.822391 11927.73874 12819.30988 0.908866498 0.958919971 0.978287437 0.907573011 0.931731508 0.797874387 0.698090096 0.414751062 0.930450925 1 13.64603098 -4.104922943 0.870131109 0.957362319 1.22E-21 0.969220474 0.029665524 0.393266166 0.183321497 0.005847796 0.381754922 7.85E-05 4.104922943 -0.957362319 down T(ph)SPDTLR ddPTM_HeLa_Curcumin_4h_R1 1 TSPDTLR 7 0 J3KP15;Q01130;J3QL05;Q01130-2 J3KP15 SRSF2 Serine/arginine-rich splicing factor 2 1 0 T(0.956)S(0.044)PDTLR 160.63 0.01997 1752000000 5817.5 5201.4 5332.5 5163.1 6024.5 6434.4 5053.2 5393.8 4731.5 4482.4 TRUE FALSE FALSE 5357.038736 5650.985839 5530.127141 5141.73646 5952.661772 5099.832909 5194.979192 7038.34479 4212.466288 4638.163066 1.154991461 1.21836722 1.19230977 1.108571731 1.283409334 1.099537217 1.120051002 1.517485412 0.908218669 1 12.17933783 -7.025984797 0.030190442 4.73E-10 2.308398681 0.493593439 0.111247999 87.55463385 1.988578032 73.87026045 77.48246767 9.42E-08 7.025984797 2.30839868 T(ph)SPDTLRR ddPTM_HeLa_Curcumin_4h_R1 1 TSPDTLRR 8 1 J3KP15;Q01130;J3QL05;Q01130-2 J3KP15 SRSF2 Serine/arginine-rich splicing factor 2 1 0 T(0.605)S(0.394)PDT(0.001)LRR 94.409 0.0095928 25041000 4790.1 3679.8 4313.8 4180.1 4131.1 5424.8 3992.1 4885.7 4425.7 3812.4 TRUE FALSE FALSE 4410.958531 3997.865515 4473.673223 4162.803854 4081.839331 4299.63533 4104.107582 6375.327439 3940.211783 3944.880616 1.118147533 1.013431306 1.134045275 1.055242036 1.034718089 1.089927871 1.040362936 1.616101489 0.998816483 1 11.94576593 -4.26025788 24.99484305 1.059286707 1.616101668 0.93351246 0.044994102 19.281366 407850.2455 0.006761288 0.056149722 5.49E-05 4.26025788 0.556814961 T(ph)SPENVQDR ddPTM_HeLa_Curcumin_4h_R1 2 TSPENVQDR 9 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 T(0.618)S(0.382)PENVQDR;T(0.868)S(0.132)PENVQDR ; 190.36 0.0026714 277690000 17272.5 15907.8 14976.1 15742.8 15837.6 18065.9 10885.3 9321 16580.6 14404.8 TRUE FALSE FALSE 15905.3634 17282.79935 15531.12744 15677.66046 15648.74696 14318.8287 11190.71222 12162.92999 14761.74966 14905.36573 1.067089778 1.159501864 1.041982312 1.051813203 1.049873398 0.960649269 0.750784142 0.816010168 0.990364808 1 13.86354415 -4.914046251 3.429488105 1.04495547 0.782823399 0.837037846 0.046594779 0.069285157 1.601639252 0.007042723 0.024166438 1.22E-05 4.914046251 -0.262132071 T(ph)SPGQFGALGACYNPGGQLGGASAGAYHAR ddPTM_HeLa_Curcumin_4h_R1 1 TSPGQFGALGACYNPGGQLGGASAGAYHAR 30 0 O00358 O00358 FOXE1 Forkhead box protein E1 1 0 T(0.5)S(0.5)PGQFGALGACYNPGGQLGGASAGAYHAR 123.57 1.73E-12 16039000 912.35 784.17 1016.9 916.65 1079.2 1520.8 1527.7 840.29 1053.9 847.95 TRUE FALSE FALSE 840.1365348 851.9501606 1054.587209 912.8571452 1066.331245 1205.368937 1570.56315 1096.490553 938.2898067 877.4161994 0.957511994 0.970976101 1.201923568 1.0403924 1.215308363 1.373771008 1.789986498 1.249681227 1.069378258 1 9.777117532 -5.459441455 1.361390833 0.992725881 1.533883217 0.638525626 0.143925569 0.167178853 0.590800859 0.020138398 0.066930777 3.47E-06 5.459441455 0.541157336 T(ph)SPGRVDLPGSSTTLTK ddPTM_HeLa_Curcumin_4h_R1 2 TSPGRVDLPGSSTTLTK 17 1 O94875-12;O94875-11;O94875-9;O94875-5;O94875-3;O94875-8;H7BXR3;O94875-4;H7BZX1;H7C1R7;H7BZK1;O94875;O94875-7;O94875-2;O94875-10 O94875-12;O94875-10 SORBS2 Sorbin and SH3 domain-containing protein 2 1 0 T(0.885)S(0.086)PGRVDLPGS(0.019)S(0.009)TTLTK;T(0.816)S(0.184)PGRVDLPGSSTTLTK ; 133.78 0.00050229 101780000 13284.7 10507.9 10683.2 11575.2 11598.1 13041.4 9692.9 8227.2 12468.1 10564.7 TRUE FALSE FALSE 12233.20198 11416.15605 11079.12879 11527.30489 11459.80023 10336.46663 9964.856687 10735.63541 11100.38062 10931.82254 1.119045057 1.044304919 1.013474995 1.054472376 1.048297317 0.94553919 0.911545779 0.982053575 1.015419029 1 13.41624632 -5.263579471 5.780095303 1.052770101 0.942240988 0.591880704 0.035664541 0.095333586 13.24314201 0.006760793 0.01636259 5.45E-06 5.263579471 -0.110529113 T(ph)SPKPAVVETVTTAKPQQIQALMDEVTK ddPTM_HeLa_Curcumin_4h_R1 6 TSPKPAVVETVTTAKPQQIQALMDEVTK 28 2 P56192;H0YI94;H0YIP0 P56192 MARS "Methionine--tRNA ligase, cytoplasmic" 1 0 T(0.5)S(0.5)PKPAVVETVTTAKPQQIQALMDEVTK;T(0.672)S(0.326)PKPAVVET(0.002)VTTAKPQQIQALMDEVTK;T(0.5)S(0.5)PKPAVVETVTTAKPQQIQALMDEVTK;T(0.495)S(0.495)PKPAVVET(0.003)VT(0.003)T(0.003)AKPQQIQALMDEVTK;T(0.496)S(0.496)PKPAVVET(0.009)VTTAKPQQIQALMDEVTK;T(0.5)S(0.5)PKPAVVETVTTAKPQQIQALMDEVTK ;;;;; 139.04 9.24E-11 409652000 11535.7 10124.73 10485.88 11898.4 10843.1 12736.3 10291.65 9138.94 12191.6 10787.6 TRUE FALSE FALSE 10622.63717 10999.86655 10874.49594 11849.16757 10713.80311 10094.64781 10580.406 11925.36074 10854.21198 11162.4683 0.951638732 0.985433172 0.974201731 1.061518587 0.959805917 0.904338319 0.947855413 1.068344422 0.972384574 1 13.44636846 -4.250477047 24.00950796 0.975237572 1.068344516 0.355560877 0.038395682 852.1410891 1866279.559 0.005584772 0.105903874 5.62E-05 4.250477047 0.093106944 T(ph)SPLKDNPS(ph)PEPQLDDIKR ddPTM_HeLa_Curcumin_4h_R1 3 TSPLKDNPSPEPQLDDIKR 19 2 Q96JC9-2;Q96JC9 Q96JC9-2 EAF1 ELL-associated factor 1 2 0 T(0.738)S(0.262)PLKDNPS(1)PEPQLDDIKR;T(0.864)S(0.136)PLKDNPS(1)PEPQLDDIKR;T(0.784)S(0.476)PLKDNPS(0.74)PEPQLDDIKR ;; 107.85 0.002858 193850000 7691.1 5963.8 6327.9 6899.1 6596 7939.4 6738.4 5044.1 8063.7 6943 TRUE FALSE FALSE 7082.341319 6479.284298 6562.417541 6870.553352 6517.347008 6292.678945 6927.461369 6582.02287 7179.132284 7184.268733 0.985812416 0.901871093 0.91344266 0.956333011 0.907169157 0.875896932 0.96425421 0.916171585 0.999285042 1 12.8106256 -7.328175787 5.771346886 0.993649064 0.920146098 0.67169959 0.024269768 0.094045117 6.07256645 0.004100313 0.00468563 4.70E-08 7.328175787 -0.073502965 T(ph)SPLKDNPSPEPQLDDIKR ddPTM_HeLa_Curcumin_4h_R1 1 TSPLKDNPSPEPQLDDIKR 19 2 Q96JC9-2;Q96JC9 Q96JC9-2 EAF1 ELL-associated factor 1 1 0 T(0.758)S(0.241)PLKDNPS(0.001)PEPQLDDIKR 59.996 0.0098501 41884000 3032.3 2888.3 3328.7 3080.2 2932.2 4068.4 2464.1 1693.9 3059.3 2616.5 TRUE FALSE FALSE 2792.290255 3137.951782 3452.06455 3067.454949 2897.23543 3224.56798 2533.236014 2210.362312 2723.702444 2707.42318 1.031346069 1.159017846 1.275036934 1.132979495 1.070108083 1.191009962 0.935663118 0.816408136 1.006012826 1 11.40270469 -4.542475296 6.571230338 1.065970937 0.843766518 0.486936981 0.090812465 0.108593926 18.60764909 0.014790411 0.060022234 2.87E-05 4.542475296 -0.222204419 T(ph)SPLVSQNNEQGSTLR ddPTM_HeLa_Curcumin_4h_R1 1 TSPLVSQNNEQGSTLR 16 0 A0A1W2PNZ9;Q15652-3;Q15652;H7BXU7 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 0 T(0.845)S(0.155)PLVSQNNEQGSTLR 166.79 0.00053199 14992000 3132.8 2960.4 2818.1 3263.5 3161.8 2843.4 2731.5 1321 2831 2206.3 TRUE FALSE FALSE 2884.835574 3216.283785 2922.541265 3249.996502 3124.0976 2253.646788 2808.138539 1723.766819 2520.446383 2282.968761 1.263633399 1.40881638 1.280149477 1.423583431 1.368436421 0.987156209 1.230038092 0.75505493 1.104021407 1 11.1566954 -4.258017495 24.41788388 1.188468055 0.755054704 0.44351634 0.153356621 217.3049876 1550542.979 0.025065658 0.243598196 5.52E-05 4.258017495 -0.433413352 T(ph)SPPGGELS(ph)PGAGR ddPTM_HeLa_Curcumin_4h_R1 2 TSPPGGELSPGAGR 14 0 Q99958 Q99958 FOXC2 Forkhead box protein C2 2 0 T(0.989)S(0.011)PPGGELS(1)PGAGR;T(0.988)S(0.012)PPGGELS(1)PGAGR ; 167.92 0.00094172 118779000 9636 8435.6 8239.4 8776.3 8830 10699.4 9537.3 7534.4 9584.7 7467.2 TRUE FALSE FALSE 8873.300432 9164.735676 8544.759412 8739.985996 8724.708017 8480.223833 9804.89097 9831.603876 8533.28239 7726.684644 1.148396866 1.186114886 1.105876557 1.131143097 1.129165796 1.097524258 1.268964818 1.272422045 1.104391182 1 12.9156338 -13.52287875 0.080054519 0.431120376 1.347406856 0.436183374 0.058261216 91.1762492 0.560202766 9.32350581 1.031044769 3.00E-14 13.52287875 0.91628648 T(ph)SPPGGELSPGAGR ddPTM_HeLa_Curcumin_4h_R1 2 TSPPGGELSPGAGR 14 0 Q99958 Q99958 FOXC2 Forkhead box protein C2 1 0 T(0.976)S(0.024)PPGGELSPGAGR;T(0.929)S(0.071)PPGGELSPGAGR ; 111.31 0.0080364 631020000 4390.8 3624.9 3953.4 3829.5 4399.1 5039.7 4098.8 1580.44 4429.1 4138.5 TRUE FALSE FALSE 4043.263547 3938.220204 4099.916482 3813.654544 4346.643606 3994.409411 4213.801297 2062.308881 3943.238811 4282.312567 0.944177587 0.919648004 0.957407106 0.890559595 1.0150225 0.932769234 0.984001338 0.481587658 0.920819942 1 12.06417439 -4.259958944 24.99998105 0.963480443 0.4815875 0.930204601 0.038500246 21.97059033 370978.5761 0.00523866 0.044284062 5.50E-05 4.259958944 -0.481892942 T(ph)SPPLLDR ddPTM_HeLa_Curcumin_4h_R1 2 TSPPLLDR 8 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 T(0.996)S(0.004)PPLLDR;T(0.999)S(0.001)PPLLDR ; 166.07 0.0018993 4847150000 11767.4 9956.6 10669.7 10990 11411.7 12453.8 11248.1 8595.9 9475.1 9739.2 TRUE FALSE FALSE 10835.99787 10817.20414 11065.12847 10944.52629 11275.62293 9870.741497 11563.69141 11216.75034 8435.705236 10077.63648 1.07525191 1.073387015 1.097988451 1.086021144 1.118875736 0.979469891 1.147460661 1.113033832 0.837071793 1 13.2988697 -9.377926933 0.366847055 0.964440807 1.093805488 0.423974125 0.066048195 2.287319435 0.377879694 0.120103314 0.016016144 4.19E-10 9.377926933 0.129364681 T(ph)SPQELSEELSR ddPTM_HeLa_Curcumin_4h_R1 1 TSPQELSEELSR 12 0 A0A1B0GVY1;Q96PU5-9;Q96PU5-4;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-7;Q96PU5;K7ERN1;Q96PU5-3 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 0 T(0.88)S(0.12)PQELSEELSR 116.9 0.011255 14957000 1996.2 1564 1777.6 1682.1 1721.1 1780.6 1342.9 1158.4 1958.1 1700.8 TRUE FALSE FALSE 1838.198664 1699.185191 1843.47942 1675.139916 1700.577007 1411.283489 1380.57816 1511.590827 1743.301329 1759.902673 1.044488818 0.965499523 1.047489414 0.951836679 0.966290371 0.801909963 0.784462789 0.858905921 0.990566896 1 10.78127993 -5.441671941 1.909957076 1.016198757 0.807983464 0.834034712 0.036422944 0.085762344 0.608802915 0.005225093 0.014494127 3.62E-06 5.441671941 -0.208215293 T(ph)SPQELSEELSRR ddPTM_HeLa_Curcumin_4h_R1 1 TSPQELSEELSRR 13 1 A0A1B0GVY1;Q96PU5-9;Q96PU5-4;Q96PU5-2;Q96PU5-6;Q96PU5-5;Q96PU5-7;Q96PU5;K7ERN1;Q96PU5-3 A0A1B0GVY1 NEDD4L E3 ubiquitin-protein ligase NEDD4-like 1 0 T(0.509)S(0.305)PQELS(0.05)EELS(0.135)RR 79.347 0.0119 6183800 1895 1997.3 2166.2 2428.8 2109.3 1431.6 1275 1247.1 2353.4 2053.8 TRUE FALSE FALSE 1745.00875 2169.937712 2246.481278 2418.750269 2084.147975 1134.670023 1310.773069 1627.335049 2095.237908 2125.169397 0.821115132 1.021065763 1.057083393 1.138144692 0.98069734 0.533919801 0.616785217 0.765743687 0.985915716 1 11.05336213 -5.269913453 24.92483464 0.953602693 0.636613132 0.724933618 0.099203313 299.9307559 882188.5215 0.017258674 0.039177234 5.37E-06 5.269913453 -0.316989562 T(ph)SPQVLGSILK ddPTM_HeLa_Curcumin_4h_R1 2 TSPQVLGSILK 11 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 T(0.999)S(0.001)PQVLGSILK;T(0.984)S(0.016)PQVLGSILK ; 178.22 0.00051626 368220000 8974.6 6991.8 8173.8 7484.2 6959.1 8338.5 5403.7 5183.8 8919.3 7666 TRUE FALSE FALSE 8264.25094 7596.140037 8476.728218 7453.232363 6876.117278 6609.001106 5555.313279 6764.316757 7940.875105 7932.392929 1.041835801 0.957610157 1.068621826 0.939594449 0.866840226 0.833166128 0.700332589 0.852746052 1.001069309 1 12.95354043 -5.675907479 1.517079525 1.018417874 0.780779436 0.806392138 0.047075595 0.10618117 0.489017655 0.006745186 0.017556265 2.11E-06 5.675907479 -0.237638438 T(ph)SPSGGTWSSVVSGAK ddPTM_HeLa_Curcumin_4h_R1 2 TSPSGGTWSSVVSGAK 16 0 F8WB06;F8VRK6 F8WB06 ATXN2 1 0 T(0.68)S(0.32)PSGGTWSSVVSGAK;T(0.982)S(0.018)PSGGTWSSVVSGAK ; 207.66 4.30E-10 87091000 5839.7 5083.6 4469.4 5358.5 5292.6 5790.9 3829 3579.5 5940.6 4767 TRUE FALSE FALSE 5377.481583 5523.003732 4635.039896 5336.327947 5229.489202 4589.802063 3936.431435 4670.873072 5288.931043 4932.652895 1.090180416 1.119682218 0.939664719 1.081837312 1.060177822 0.930493623 0.798035361 0.946929202 1.072228506 1 12.26814805 -5.112383533 3.910854 1.045392775 0.870507073 0.615489892 0.058799273 0.115550715 3.085304747 0.008445965 0.023474676 7.72E-06 5.112383533 -0.174885701 T(ph)SPSGGTWSSVVSGVPR ddPTM_HeLa_Curcumin_4h_R1 4 TSPSGGTWSSVVSGVPR 17 0 H0YH87;A0A2R8Y7P6;A0A2R8YDM9;A0A5F9ZHH4;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A2R8Y5A6;A0A5F9ZHX3;A0A5F9ZHW5;Q99700-2;Q99700-5;Q99700-4;Q99700 H0YH87 ATXN2 Ataxin-2 1 0 T(0.895)S(0.099)PS(0.005)GGTWSSVVSGVPR;T(0.858)S(0.142)PS(0.001)GGTWSSVVSGVPR;T(0.969)S(0.028)PS(0.002)GGTWSSVVSGVPR;T(0.978)S(0.022)PSGGTWSSVVSGVPR ;;; 240.5 6.42E-30 287916000 8342.4 6474 7772.5 7768.5 7614.9 9146 6476 4656.2 8093.1 6857.9 TRUE FALSE FALSE 7682.090237 7033.583712 8060.555687 7736.356005 7524.097291 7249.016503 6657.699131 6075.853945 7205.307178 7096.211515 1.082562184 0.991174474 1.135895635 1.090209331 1.060297777 1.021533319 0.938204719 0.856210942 1.01537379 1 12.7928333 -4.573277731 1.927246398 1.048789721 0.847847101 0.700916666 0.041887182 0.21477697 1.26686787 0.006744242 0.061334833 2.67E-05 4.573277731 -0.20094262 T(ph)SPSGGTWSSVVSGVPRLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 TSPSGGTWSSVVSGVPRLSPK 21 1 H0YH87;A0A2R8Y7P6;A0A2R8YDM9;A0A5F9ZHH4;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A2R8Y5A6;A0A5F9ZHX3;A0A5F9ZHW5;Q99700-2;Q99700-5;Q99700-4;Q99700 H0YH87 ATXN2 Ataxin-2 2 0 T(0.685)S(0.266)PS(0.253)GGT(0.03)WS(0.017)S(0.03)VVS(0.161)GVPRLS(0.558)PK 67.075 0.0060496 84546000 3439.1 2699.7 2782.9 3006.3 2788.6 3623.2 1830.9 1541.4 3470.1 2850.2 TRUE FALSE FALSE 3166.891606 2933.050038 2886.036722 2993.860727 2755.347766 2871.707478 1882.270126 2011.365764 3089.438712 2949.244238 1.073797675 0.994509034 0.978568233 1.015128109 0.934255539 0.973709617 0.638221176 0.681993623 1.047535729 1 11.52612959 -4.805815958 4.624118182 1.018453284 0.65643946 0.923663629 0.039228166 0.03845064 1.773274081 0.006686266 0.022596054 1.56E-05 4.805815958 -0.362013824 AGT(ph)PVSELTK ddPTM_HeLa_Curcumin_4h_R1 2 AGTPVSELTK 10 0 O75113 O75113 N4BP1 NEDD4-binding protein 1 1 0 AGT(0.994)PVS(0.003)ELT(0.002)K;AGT(1)PVSELTK ; 192.44 0.0002728 91795000 16236.9 13459 15425.3 13594.7 15331 13993.6 11635.4 4237.7 15239.2 12268 TRUE FALSE FALSE 14951.73223 14622.33599 15996.97519 13538.44873 15148.18784 11091.16962 11961.85801 5529.755222 13567.49789 12694.31209 1.177829262 1.151880928 1.260168734 1.066497234 1.193305138 0.873711749 0.942300609 0.435608892 1.068785594 1 13.6318946 -4.104910716 1.18967866 1.106452771 1.41E-13 0.820928269 0.094984291 0.719055097 0.658614039 0.015560966 1.069321856 7.85E-05 4.104910716 -1.106452771 down QQSSSSKGDS(ph)PELKPR ddPTM_HeLa_Curcumin_4h_R1 1 QQSSSSKGDSPELKPR 16 2 H0Y3A3;A0A3B3ITG3;Q5VWQ8-3;Q5VWQ8-4;Q5VWQ8-2;Q5VWQ8-5;Q5VWQ8 H0Y3A3 DAB2IP Disabled homolog 2-interacting protein 1 0 QQS(0.031)S(0.031)S(0.036)S(0.036)KGDS(0.866)PELKPR 52.19 0.016226 22140000 8178.2 6491.9 7414 8087.7 7428.4 8730.5 5806.5 2489.4 7884.1 7616.7 TRUE FALSE FALSE 7530.88684 7053.030909 7688.769362 8054.23524 7339.821182 6919.695887 5969.414763 3248.4066 7019.233955 7881.379758 0.95552899 0.894897991 0.975561335 1.021932135 0.931286324 0.877980265 0.757407325 0.412162172 0.890609788 1 12.9442325 -4.104237879 1.140400211 0.973325178 1.34E-13 0.93589685 0.042785331 0.301719327 0.251714755 0.005537671 0.38025959 7.87E-05 4.104237879 -0.973325178 down GRLPNNS(ph)SRPSTPTINVLESK ddPTM_HeLa_Curcumin_4h_R1 1 GRLPNNSSRPSTPTINVLESK 21 2 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 0 GRLPNNS(0.327)S(0.327)RPS(0.262)T(0.067)PT(0.018)INVLESK 46.833 0.012825 35378000 4542.6 3520.7 3971.7 3696.1 3982.6 3845.4 3059.8 1207.9 3852 3621.1 TRUE FALSE FALSE 4183.048417 3825.01362 4118.894696 3680.806518 3935.110096 3047.820693 3145.649753 1576.18315 3429.445237 3746.932955 1.116392651 1.020838554 1.099270989 0.982351849 1.050221646 0.813417462 0.839526565 0.420659555 0.915267307 1 11.87149445 -4.103884199 0.882196565 1.054421223 1.84E-13 0.84865726 0.075333462 0.601042448 0.288181648 0.009906669 0.651002247 7.87E-05 4.103884199 -1.054421223 down TLS(ph)PSLSR ddPTM_HeLa_Curcumin_4h_R1 1 TLSPSLSR 8 0 A0A1B0GV45 A0A1B0GV45 1 0 T(0.231)LS(0.767)PS(0.001)LSR 117.31 0.0091143 7850300 3154.1 2370.1 2418.7 3188.5 2728.7 3352.6 2304.6 879.27 3304.6 2683.6 TRUE FALSE FALSE 2904.449657 2574.960883 2508.33915 3175.306832 2696.162035 2657.232968 2369.260873 1147.355375 2942.093648 2776.8549 1.045949378 0.927293998 0.903302203 1.143490368 0.970940914 0.956921792 0.853217384 0.41318521 1.059505719 1 11.43923608 -4.10350116 1.524298248 1.011279404 2.31E-21 0.881243426 0.065088539 0.369862692 0.585454926 0.009043882 0.625227405 7.88E-05 4.10350116 -1.011279404 down T(ph)SQETADVK ddPTM_HeLa_Curcumin_4h_R1 4 TSQETADVK 9 0 H3BVG0;Q8N1F7;H3BNN5;H3BV11;H3BRI8;H3BM93 H3BVG0 NUP93 Nuclear pore complex protein Nup93 1 0 T(0.983)S(0.017)QETADVK;T(0.851)S(0.149)QETADVK;T(0.985)S(0.015)QETADVK;T(0.983)S(0.017)QETADVK ;;; 155.47 0.0035379 107842000 21880.7 27207.9 24654.9 18821.6 22135.1 23760.2 17126.5 16963.4 17926.7 21912.5 TRUE FALSE FALSE 20148.81951 29559.62964 25568.63228 18743.72121 21871.15339 18832.06669 17607.0235 22135.46257 15960.18586 22673.95774 0.888632665 1.303681959 1.127665164 0.826662968 0.96459355 0.830559309 0.776530665 0.976250499 0.703899427 1 14.46874862 -6.225794061 24.93322072 0.990752568 0.871970802 0.145372432 0.15549867 892.3918538 624211.2072 0.021056904 0.034918032 5.95E-07 6.225794061 -0.118781766 T(ph)SRDT(ph)SPSSGSAVSSSK ddPTM_HeLa_Curcumin_4h_R1 1 TSRDTSPSSGSAVSSSK 17 1 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;Q8NEY8-7 F8WF16 PPHLN1 Periphilin-1 2 0 T(0.8)S(0.2)RDT(0.715)S(0.254)PS(0.018)S(0.013)GSAVSSSK 160.45 0.00012928 41368000 7074.1 6202.4 6301 6405.8 7654.5 6990.5 7034 4703.9 5616.3 5550.9 TRUE FALSE FALSE 6514.17752 6738.507819 6534.520603 6379.294497 7563.225087 5540.591501 7231.355109 6138.097456 5000.205941 5743.793362 1.13412463 1.173180753 1.13766638 1.110641365 1.31676483 0.964622359 1.258985944 1.068648726 0.870540708 1 12.48778813 -8.935153611 0.64750957 0.992573939 1.150751861 0.37248965 0.100872621 0.799877897 0.590437258 0.067996331 0.018711421 1.16E-09 8.935153611 0.158177923 T(ph)SRDTSPSSGSAVSSSK ddPTM_HeLa_Curcumin_4h_R1 1 TSRDTSPSSGSAVSSSK 17 1 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;Q8NEY8-7 F8WF16 PPHLN1 Periphilin-1 1 0 T(0.492)S(0.492)RDT(0.013)S(0.003)PSSGSAVSSSK 71.54 0.014629 2721100 2074.3 2143.3 1878.4 2195.6 2195.5 2324.1 1846.5 1556.2 1853.7 2150.4 TRUE FALSE FALSE 1910.116966 2328.557302 1948.015156 2186.515189 2169.320096 1842.055462 1898.30782 2030.678216 1650.353748 2225.12624 0.858430831 1.046483233 0.875462759 0.982647703 0.97492001 0.827843126 0.85312365 0.912612588 0.74168994 1 11.11967147 T(ph)SSDPVLLK ddPTM_HeLa_Curcumin_4h_R1 1 TSSDPVLLK 9 0 Q9BRG2;Q9BRG2-2 Q9BRG2 SH2D3A SH2 domain-containing protein 3A 1 0 T(0.866)S(0.01)S(0.123)DPVLLK 140.78 0.0067648 21462000 7998.9 7166.3 7900.2 8208.7 7659 9977.4 8394.8 7310 8511.8 7591.3 TRUE FALSE FALSE 7365.778625 7785.72304 8192.988362 8174.734574 7567.671427 7907.974772 8630.335495 9538.785349 7578.076835 7855.09711 0.937706883 0.991168273 1.043015541 1.040691727 0.963409022 1.006731637 1.0986924 1.214343402 0.964733692 1 12.9394134 -1.000000008 0.651926998 0.977458921 23.1362972 0.814121316 0.033113461 69.02701566 0.410227551 0.006700099 2213.03025 0.099999998 1.000000008 22.15883827 T(ph)SSEDNLYLAVLR ddPTM_HeLa_Curcumin_4h_R1 3 TSSEDNLYLAVLR 13 0 Q15149-4 Q15149-4 PLEC Plectin 1 0 T(0.852)S(0.012)S(0.136)EDNLYLAVLR;T(0.769)S(0.116)S(0.116)EDNLYLAVLR;T(0.83)S(0.151)S(0.019)EDNLYLAVLR ;; 252.46 1.71E-35 2020900000 7350.44 6060.91 6673.58 6840.42 7373.55 7134.7 5047.49 4269.44 7434.26 6224.43 TRUE FALSE FALSE 6768.644918 6584.788054 6920.908745 6812.116155 7285.625232 5654.882795 5189.108985 5571.172602 6618.740278 6440.728479 1.050912942 1.022366969 1.07455372 1.057662371 1.131180309 0.877988074 0.805671129 0.864991067 1.027638457 1 12.65300816 -5.109549935 5.69366618 1.036843905 0.836824947 0.85460963 0.038143108 0.066288589 2.918338245 0.005876395 0.015380333 7.77E-06 5.109549935 -0.200018958 T(ph)SSEEEDSRREEPSLLLVLK ddPTM_HeLa_Curcumin_4h_R1 1 TSSEEEDSRREEPSLLLVLK 20 2 A0A087WZV0;O43314-2;O43314;D6RBU4 A0A087WZV0 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 1 0 T(0.641)S(0.175)S(0.175)EEEDS(0.007)RREEPS(0.003)LLLVLK 62.823 0.0056024 21634000 3730 2449.8 3121.9 3243.1 3242.7 3573 2813.2 2600.5 3795 3110.6 TRUE FALSE FALSE 3434.766564 2661.549796 3237.60036 3229.680912 3204.03292 2831.919524 2892.130821 3393.380479 3378.697995 3218.693118 1.067130801 0.82690387 1.005874198 1.003413744 0.995445295 0.879835206 0.898541959 1.05427276 1.049711131 1 11.65225932 T(ph)SSFTEQLDEGTPNR ddPTM_HeLa_Curcumin_4h_R1 1 TSSFTEQLDEGTPNR 15 0 Q13439-3;Q13439-4;Q13439;Q13439-5;Q86W71;E7EVX2;C9J0Y3;C9JHJ5 Q13439-3 GOLGA4 Golgin subfamily A member 4 1 0 T(0.331)S(0.331)S(0.331)FT(0.007)EQLDEGTPNR 111.62 0.0019561 3115400 1107.6 1280.5 1448.4 1492.5 1072.9 807.78 713.3 799.71 1387 1246 TRUE FALSE FALSE 1019.932291 1391.180714 1502.078978 1486.32443 1060.106368 640.2373224 733.3132783 1043.537898 1234.84957 1289.298407 0.791075429 1.07902151 1.165035937 1.152816464 0.822235072 0.496578076 0.568769242 0.809384307 0.957768631 1 10.3323705 -5.494821052 7.231319087 0.95303504 0.624585573 0.615458512 0.135244244 0.141632199 27.95577469 0.023114851 0.050585595 3.20E-06 5.494821052 -0.328449468 T(ph)SSLTQFPPSQSEER ddPTM_HeLa_Curcumin_4h_R1 4 TSSLTQFPPSQSEER 15 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4 B7Z7F3 RANBP3 Ran-binding protein 3 1 0 T(0.651)S(0.168)S(0.168)LT(0.012)QFPPSQSEER;T(0.379)S(0.379)S(0.232)LT(0.009)QFPPSQSEER;T(0.464)S(0.072)S(0.464)LTQFPPSQSEER;T(0.454)S(0.454)S(0.092)LTQFPPSQSEER ;;; 209.33 2.28E-09 48578200 11107.1 9318.1 9713.6 10236.5 10752.6 12424.1 12435.3 13755.2 11766.3 10608.7 TRUE FALSE FALSE 10227.96131 10123.51504 10073.59456 10194.14408 10624.38227 9847.201612 12784.20105 17949.09716 10475.56633 10977.35154 0.931733058 0.922218352 0.917670763 0.928652421 0.967845681 0.897047123 1.164597946 1.635102702 0.954289046 1 13.4222424 -4.321839716 2.436583976 0.953788864 1.741437694 0.974710736 0.033979631 0.058141667 0.46117224 0.005719431 0.089906555 4.77E-05 4.321839716 0.787648831 T(ph)SSPRSPPSSSEIFTPAHEENVR ddPTM_HeLa_Curcumin_4h_R1 1 TSSPRSPPSSSEIFTPAHEENVR 23 1 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 0 T(0.296)S(0.296)S(0.296)PRS(0.099)PPS(0.004)S(0.004)S(0.004)EIFTPAHEENVR 61.16 0.002338 28116000 1375.3 934.64 998.28 1369.2 1617.9 1923 1288.4 1487.6 1939.1 1475 TRUE FALSE FALSE 1266.443554 1015.426117 1035.277135 1363.534613 1598.607599 1524.148123 1324.549036 1941.162392 1726.385581 1526.25614 0.829771308 0.665305181 0.678311528 0.893385178 1.047404533 0.998618832 0.867841905 1.271845754 1.131124413 1 10.57578138 -4.258927539 24.48913131 0.894525168 1.271845931 0.374715119 0.143355586 140.142253 1366198.865 0.019391874 0.176144845 5.51E-05 4.258927539 0.377320763 T(ph)SSTCS(ph)NESLSVGGTSVTPR ddPTM_HeLa_Curcumin_4h_R1 2 TSSTCSNESLSVGGTSVTPR 20 0 A0A3B3IRT3;O60343-2;O60343-3;O60343;Q5JU47 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 2 0 T(0.515)S(0.191)S(0.189)T(0.228)CS(0.854)NES(0.019)LS(0.005)VGGTSVTPR;T(0.66)S(0.059)S(0.266)T(0.017)CS(0.973)NES(0.024)LS(0.001)VGGTSVTPR ; 136.68 0.0005088 5998400 2682.3 1973.45 2250 2348.98 2054.58 2755.02 2039.77 1075.3 2983.3 2063.67 TRUE FALSE FALSE 2469.993125 2144.026224 2333.386979 2339.260543 2030.080475 2183.597797 2097.000456 1403.15402 2656.039454 2135.382379 1.15669828 1.004047915 1.092725594 1.095476186 0.950687097 1.02257929 0.982025738 0.657097311 1.243823814 1 11.06027872 -3.80883893 1.182919781 1.066193953 1.18E-19 0.709395173 0.079661818 1.4671897 0.814711318 0.010351611 2.496855156 0.000155296 3.80883893 -1.066193953 T(ph)SSVVTLEVAK ddPTM_HeLa_Curcumin_4h_R1 1 TSSVVTLEVAK 11 0 A8MQ02;J3KN01;P55196-3;P55196;P55196-5;Q5TIG5;P55196-2;P55196-6;P55196-1 A8MQ02 MLLT4 Afadin 1 0 T(0.999)S(0.001)SVVTLEVAK 223.77 2.54E-11 6953700 2577.2 1917.4 2158.9 2457.3 2435.3 2652.5 2020.5 2237 2327.9 2341.2 TRUE FALSE FALSE 2373.211901 2083.131512 2238.910733 2447.132344 2406.260638 2102.3416 2077.189792 2919.051002 2072.535194 2422.556526 0.979631177 0.859889745 0.924193392 1.01014458 0.993273268 0.86781942 0.857437079 1.204946498 0.855515722 1 11.24231461 -7.502644369 19.30096246 0.99101431 0.951625094 0 0.106223392 40.07355496 38230.45337 0.016121369 0.017338515 3.14E-08 7.502644369 -0.039389216 T(ph)STSLGSAFGVQLDS(ph)RK ddPTM_HeLa_Curcumin_4h_R1 1 TSTSLGSAFGVQLDSRK 17 1 Q70Z35-4;Q70Z35 Q70Z35-4 PREX2 "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein" 2 0 T(0.31)S(0.31)T(0.31)S(0.071)LGSAFGVQLDS(1)RK 115.29 0.001324 3992300 11502 9075.8 9282.3 10150 10208 12560 8761.8 10031 12208 9495.1 TRUE FALSE FALSE 10591.60456 9860.271711 9626.310204 10108.00199 10086.27627 9954.91442 9007.632527 13089.40572 10868.81294 9825.054018 1.078019983 1.003584478 0.979771733 1.028798617 1.02658736 1.013217271 0.916802341 1.332247711 1.106234421 1 13.26224962 -4.249048165 24.99136768 1.022710076 1.332247903 0.787059131 0.04911152 664.7486657 1340683.071 0.006403293 0.153287886 5.64E-05 4.249048165 0.309537826 T(ph)SVQTEDDQLIAGQSAR ddPTM_HeLa_Curcumin_4h_R1 1 TSVQTEDDQLIAGQSAR 17 0 G3XAM7;P35221-3;P35221;P35221-2;A0A0A0MTJ6;A0A0A0MRI5;P26232-4;P26232-6;P26232-3;P26232-2;P26232-5;P26232 G3XAM7 CTNNA1;CTNNA2 Catenin alpha-1;Catenin alpha-2 1 0 T(0.5)S(0.5)VQTEDDQLIAGQSAR 277.07 4.25E-65 24078000 2164 1676 1752.9 1774.1 2048.2 2332.9 1574.5 723.45 2142.6 1240 TRUE FALSE FALSE 1992.717117 1820.865972 1817.864016 1766.759244 2023.776553 1849.030243 1618.676232 944.0265746 1907.562141 1283.089908 1.553061173 1.419125785 1.416786154 1.376956699 1.577267922 1.441076133 1.261545448 0.735744681 1.486694057 1 10.32540655 -4.270257217 4.048039987 1.329901101 0.688645866 0.565224757 0.165776535 0.186029343 6.447675376 0.03222048 0.343074359 5.37E-05 4.270257217 -0.641255235 T(ph)T(ph)ELTVTAPLT(ph)DK ddPTM_HeLa_Curcumin_4h_R1 1 TTELTVTAPLTDK 13 0 Q9NZN1 Q9NZN1 IL1RAPL1 Interleukin-1 receptor accessory protein-like 1 3 0 T(0.972)T(0.972)ELT(0.054)VT(0.026)APLT(0.976)DK 44.616 0.019046 15598000 952.43 1160.3 910.88 986.82 827.24 1279.4 797.54 918.72 1578.6 1018.3 TRUE FALSE FALSE 877.0441605 1260.591162 944.6380141 982.7368003 817.3757033 1014.038018 819.9168259 1198.833499 1405.431529 1053.685849 0.832358298 1.196363378 0.89650821 0.932665843 0.775729981 0.962372247 0.778141632 1.1377523 1.333824053 1 10.04122908 T(ph)T(ph)LPT(ph)FQS(ph)PEFS(ph)VTR ddPTM_HeLa_Curcumin_4h_R1 1 TTLPTFQSPEFSVTR 15 0 Q5QPE4;Q9Y5X3 Q5QPE4 SNX5 Sorting nexin-5 5 0 T(1)T(1)LPT(0.997)FQS(0.997)PEFS(0.558)VT(0.448)R 48.053 0.0095961 0 273.47 197.96 238.69 0 174.55 164.78 211.1 293.45 270.12 176.24 TRUE FALSE FALSE 251.8245609 215.0707803 247.5360614 0 172.4686053 130.6027705 217.0228979 382.9215541 240.4885118 182.3643269 1.380887179 1.179346772 1.357371069 0 0.945736528 0.716164026 1.190051265 2.099761289 1.31872563 1 7.510679735 T(ph)T(ph)SKRRGK ddPTM_HeLa_Curcumin_4h_R1 1 TTSKRRGK 8 3 Q9NYL2-2 Q9NYL2-2 ZAK Mitogen-activated protein kinase kinase kinase MLT 2 0 T(0.667)T(0.667)S(0.667)KRRGK 64.803 0.0080055 0 1662.2 1432.1 1544.4 1439.7 1689.5 1898.9 1381.2 1732.1 1522.1 1146.1 TRUE FALSE FALSE 1530.635116 1555.884343 1601.636823 1433.742903 1669.353816 1505.046735 1419.952755 2260.209316 1355.129438 1185.92689 1.290665664 1.311956375 1.350535886 1.208963989 1.407636365 1.26908897 1.197335828 1.905858899 1.142675362 1 10.21179936 -1 0.038110878 5.82E-12 3.422831897 0.42203466 0.172568 492.7913218 1.447111478 37.01767912 112.3252527 0.1 1 3.422831897 T(ph)T(ph)T(ph)EDENEKLR ddPTM_HeLa_Curcumin_4h_R1 1 TTTEDENEKLR 11 1 E9PJP2;Q5TF21 E9PJP2 SOGA3 Protein SOGA3 3 0 T(1)T(1)T(1)EDENEKLR 62.338 0.0090875 0 1777 1438.3 1727 1670.6 1972.8 2462.7 2146 2140.2 1564 1677.9 TRUE FALSE FALSE 1636.348575 1562.620243 1791.004139 1663.6875 1949.275648 1951.90826 2206.210984 2792.737128 1392.433113 1736.2069 0.942484778 0.900019602 1.031561468 0.95823113 1.122720828 1.124237128 1.270707416 1.608527836 0.801997223 1 10.76172317 -2.651451568 0.611354379 0.967133191 5.880374277 0.90263167 0.067756285 2.7751145 0.152011871 0.007808855 14.89601942 0.002231251 2.651451568 4.913241086 T(ph)T(ph)T(ph)LRSRPR ddPTM_HeLa_Curcumin_4h_R1 1 TTTLRSRPR 9 2 Q96J86-4 Q96J86-4 3 0 T(1)T(1)T(1)LRS(0.001)RPR 62.107 0.019385 4930900 1661.4 2166.7 1481.5 1417.9 1298.6 1340.7 1033.9 553.25 1390 1453.5 TRUE FALSE FALSE 1529.898437 2353.979893 1536.405693 1412.033105 1283.115043 1062.623707 1062.908451 721.9333782 1237.520478 1504.009017 1.017213607 1.565136822 1.021540214 0.93884617 0.853129887 0.706527484 0.706716808 0.480006017 0.822814534 1 10.5545975 -5.33284702 1.171412576 1.056100366 0.568391804 0.534403351 0.185682695 0.328460078 0.80844233 0.028219865 0.120457343 4.65E-06 5.33284702 -0.487708561 T(ph)TKSPSDSGYSYETIGK ddPTM_HeLa_Curcumin_4h_R1 1 TTKSPSDSGYSYETIGK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(0.34)T(0.34)KS(0.282)PS(0.036)DS(0.002)GYSYETIGK 84.975 0.0056174 74919000 3911.9 3481.7 3746.2 3635.2 3416.5 3715.7 2553.7 2999.1 4146.4 3529.5 TRUE FALSE FALSE 3602.268987 3782.642634 3885.037467 3620.158506 3375.760469 2945.021935 2625.349949 3913.511784 3691.550294 3652.149862 0.986342051 1.035730399 1.063767264 0.991240404 0.924321453 0.806380364 0.718850553 1.071563855 1.010788284 1 11.83453025 -5.578985212 3.26662787 1.002623138 0.851763952 0.375213473 0.085795994 0.17909954 3.891167442 0.011648242 0.02543733 2.64E-06 5.578985212 -0.150859186 T(ph)TKTPEDGDYSYEIIEK ddPTM_HeLa_Curcumin_4h_R1 2 TTKTPEDGDYSYEIIEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(0.677)T(0.171)KT(0.084)PEDGDY(0.026)S(0.039)Y(0.003)EIIEK;T(0.342)T(0.342)KT(0.296)PEDGDY(0.016)S(0.003)YEIIEK ; 85.224 0.0055122 227113000 11910.2 8923.3 9839.6 10249.9 9409.2 11821.9 9102.8 13943.4 11878.7 9260.9 TRUE FALSE FALSE 10967.4951 9694.590291 10204.26423 10207.48863 9297.001435 9369.90468 9358.200069 18194.67847 10575.63633 9582.715586 1.144508047 1.011674635 1.064861431 1.065197912 0.970184428 0.977792213 0.976570784 1.898697536 1.1036158 1 13.22621883 -4.25850794 24.9994621 1.048161656 1.898697845 0.953410891 0.057214809 49.58261577 422820.7603 0.009691878 0.091111059 5.51E-05 4.25850794 0.850536189 T(ph)TPDQELVPASEPVWERPWSVEEIRR ddPTM_HeLa_Curcumin_4h_R1 1 TTPDQELVPASEPVWERPWSVEEIRR 26 2 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q9Y4E1-5;A0A0A0MT65 A0A0A0MR88 FAM21C WASH complex subunit FAM21C 1 0 T(0.5)T(0.5)PDQELVPASEPVWERPWSVEEIRR 53.469 0.0039267 16164000 1076.9 1093.2 908.62 1011.5 782.66 1046.9 781.47 779.72 1311.3 1042.6 TRUE FALSE FALSE 991.6622287 1187.691337 942.2942565 1007.314681 773.3272907 829.761139 803.395945 1017.453039 1167.453671 1078.830272 0.919201337 1.100906572 0.873440689 0.933710062 0.716820162 0.769130382 0.744691696 0.943107609 1.082147675 1 10.07525219 -5.886157172 5.491984742 0.964907099 0.788805037 0.533113223 0.086893796 0.122443685 5.460223843 0.011392611 0.020931263 1.30E-06 5.886157172 -0.176102063 T(ph)TPNSGDVQVTEDAVR ddPTM_HeLa_Curcumin_4h_R1 1 TTPNSGDVQVTEDAVR 16 0 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 0 T(0.905)T(0.095)PNSGDVQVTEDAVR 208.85 3.33E-10 27349000 6561.7 6132.3 6826.1 5583.9 6975.6 7857.2 6688.2 6230.1 6320.5 5703.3 TRUE FALSE FALSE 6042.334521 6662.348687 7079.081271 5560.795301 6892.420526 6227.528151 6875.852892 8129.62881 5627.156963 5901.48925 1.023866056 1.128926683 1.199541501 0.942269835 1.16791207 1.055246885 1.165104705 1.377555472 0.953514736 1 12.52686335 -1 0.518016659 1.026708653 12.78757916 0.580795451 0.082089539 50.75532954 0.464606088 0.014973845 658.8353248 0.1 1 11.7608705 T(ph)TPNSGDVQVTEDAVRR ddPTM_HeLa_Curcumin_4h_R1 2 TTPNSGDVQVTEDAVRR 17 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 0 T(0.583)T(0.157)PNS(0.26)GDVQVTEDAVRR;T(0.6)T(0.354)PNS(0.047)GDVQVTEDAVRR ; 121.47 0.00030509 62684000 3434.1 2842.7 3088.9 3172.3 2669 4163.9 3028.9 3115.6 3334.4 3443.4 TRUE FALSE FALSE 3162.287361 3088.410321 3203.377351 3159.173863 2637.173918 3300.260203 3113.882782 4065.532098 2968.624662 3563.057894 0.887520623 0.866786455 0.899052849 0.886646795 0.740143438 0.926243778 0.8739355 1.141023306 0.833167675 1 11.79890021 -9.149797419 0.883642936 1.000583417 0.895362233 0 0.106325883 0.905367651 1.265479825 0.061396372 0.017329969 7.08E-10 9.149797419 -0.105221183 T(ph)TPSYVAFTDTER ddPTM_HeLa_Curcumin_4h_R1 1 TTPSYVAFTDTER 13 0 P11142;E9PKE3;E9PNE6;P11142-2;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PPY6;E9PN25;E9PI65;A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;Q53FA3;P34931;P17066;P48741;P54652 P11142;A0A0G2JIW1;P17066;P54652 HSPA8;HSPA1B;HSPA1A;HSPA1L;HSPA6;HSPA7;HSPA2 Heat shock cognate 71 kDa protein;Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 1-like;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7;Heat shock-related 70 kDa protein 2 1 0 T(0.533)T(0.11)PS(0.358)YVAFTDTER 118.52 0.0076636 13134000 1567.9 1038.8 1456.3 1434.5 1555.4 1646.4 1316.1 1064.5 1411.3 1252.6 TRUE FALSE FALSE 1443.799061 1128.589243 1510.271759 1428.564419 1536.852871 1304.918081 1353.026224 1389.06115 1256.483921 1296.127757 1.113932676 0.870739198 1.165218283 1.10217871 1.185726378 1.006781989 1.043898811 1.071700797 0.969413636 1 10.33999221 -9.573609074 1.258787876 0.998659702 1.074407969 0.131921076 0.084330542 0.937654535 2.584370491 0.062951594 0.01365685 2.67E-10 9.573609074 0.075748267 T(ph)TPTQPSEQK ddPTM_HeLa_Curcumin_4h_R1 2 TTPTQPSEQK 10 0 O95104-2;O95104-3;O95104 O95104-2 SCAF4 "Splicing factor, arginine/serine-rich 15" 1 0 T(0.869)T(0.131)PTQPSEQK;T(0.879)T(0.121)PTQPSEQK ; 169.82 0.0014287 107524000 12839.6 10955.7 11664.1 10846.8 12127.1 14533.4 12983.2 12056.4 10926.1 9403.4 TRUE FALSE FALSE 11823.33211 11902.66189 12096.38181 10801.91882 11982.49225 11519.00901 13347.47365 15732.34086 9727.534166 9730.16745 1.215121135 1.223274106 1.243183313 1.110147268 1.231478524 1.18384489 1.371761968 1.616862293 0.999729369 1 13.24824892 -1 0.412641853 1.104845584 9.539647835 0.77034968 0.081822529 27.46396691 0.317915941 0.022859535 192.1627519 0.1 1 8.434802251 SSTGPEPPAPT(ph)PLLAER ddPTM_HeLa_Curcumin_4h_R1 2 SSTGPEPPAPTPLLAER 17 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 SSTGPEPPAPT(1)PLLAER;SSTGPEPPAPT(1)PLLAER ; 236.75 9.45E-23 53078000 4597.8 3761.2 3715.6 4412.2 4517.7 7102.2 6071.5 10048.5 4922.9 4075.3 TRUE FALSE FALSE 4233.879278 4086.301368 3853.303405 4393.943485 4463.829378 5629.123662 6241.849949 13112.24139 4382.870186 4216.916372 1.004022586 0.969025944 0.913772782 1.041980229 1.058552977 1.334890988 1.480192965 3.109438328 1.039354305 1 12.0419727 -1.947334956 0.957989419 0.9951309 200 0.985064803 0.076677578 11.72492606 0.145845288 0.011036856 4963.938238 0.011289249 1.947334956 199.0048691 up T(ph)TSISPALAR ddPTM_HeLa_Curcumin_4h_R1 2 TTSISPALAR 10 0 Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3;Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5 Q9UKE5-8 TNIK TRAF2 and NCK-interacting protein kinase 1 0 T(0.683)T(0.008)S(0.001)IS(0.308)PALAR;T(0.975)T(0.011)S(0.007)IS(0.007)PALAR ; 118.23 0.014125 164728000 6857.7 6284.6 6958.7 6916.9 6660.2 8635.9 6074.9 5360 7649.8 7075.2 TRUE FALSE FALSE 6314.905809 6827.81282 7216.595543 6888.279701 6580.781465 6844.716993 6245.345344 6994.239326 6810.636079 7321.062673 0.862566828 0.932625921 0.985730606 0.940885225 0.898883367 0.934934899 0.853065412 0.955358482 0.930279712 1 12.83783736 -9.587523386 1.383837289 0.999889231 0.913296226 0.044118421 0.043974365 0.366468524 1.26128963 0.029280458 0.006847562 2.59E-10 9.587523386 -0.086593005 T(ph)TSPLEEEEREIK ddPTM_HeLa_Curcumin_4h_R1 3 TTSPLEEEEREIK 13 1 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 T(0.333)T(0.333)S(0.333)PLEEEEREIK;T(0.732)T(0.134)S(0.134)PLEEEEREIK;T(0.852)T(0.136)S(0.013)PLEEEEREIK ;; 174.21 0.0020116 108782000 13535.7 10783.1 10149 13174.7 10615.3 13149 11419.2 11962.8 13918.7 11772.3 TRUE FALSE FALSE 12464.33506 11715.14312 10525.13087 13120.18658 10488.71948 10421.74918 11739.59202 15610.20265 12391.85343 12181.38655 1.02322794 0.961724929 0.864033895 1.077068405 0.861044795 0.855547038 0.963732 1.281479952 1.017277744 1 13.57239074 -7.257677743 23.38928276 1.010968749 0.969819969 0.009708481 0.120469169 487.653651 3032156.284 0.01953174 0.023391937 5.52E-08 7.257677743 -0.04114878 T(ph)TSPPEVSGYSYEK ddPTM_HeLa_Curcumin_4h_R1 2 TTSPPEVSGYSYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(0.626)T(0.028)S(0.346)PPEVSGYSYEK;T(0.761)T(0.12)S(0.12)PPEVSGYSYEK ; 211.83 1.80E-09 1538000000 6538.5 6092.2 6311.9 6508.4 6328.5 7021.4 5398.2 5338.7 7631.2 6263.9 TRUE FALSE FALSE 6020.970826 6618.782622 6545.824567 6481.469965 6253.036771 5565.082493 5549.658963 6966.445054 6794.076452 6481.570059 0.928937089 1.021169649 1.009913417 0.999984557 0.96474106 0.858600994 0.856221396 1.074808263 1.048214613 1 12.66212761 -5.498710058 24.19191599 0.976197586 0.920704608 0.126845262 0.065935199 776.5642091 777309.3951 0.008869931 0.019723714 3.17E-06 5.498710058 -0.055492979 LSS(ph)LRAS(ph)TSKSESSQK ddPTM_HeLa_Curcumin_4h_R1 1 LSSLRASTSKSESSQK 16 2 P62753;A2A3R5 P62753 RPS6 40S ribosomal protein S6 2 0 LS(0.149)S(0.853)LRAS(0.997)T(0.001)SKSESSQK 93.5 0.0033863 61890000 5459.6 4400.4 4776 4612.7 4148.3 5766.9 3650.7 1500.4 5902.5 4404.3 TRUE FALSE FALSE 5027.466899 4780.750968 4953.002761 4593.61387 4098.834232 4570.779934 3753.128817 1957.865053 5255.010517 4557.349097 1.103155978 1.049020136 1.086816624 1.007957427 0.899390006 1.002947072 0.823533317 0.429606118 1.15308492 1 12.15397917 -4.103007644 1.179310955 1.043663264 3.85E-21 0.900977307 0.062219176 0.440308384 0.39450953 0.008867862 0.613505276 7.89E-05 4.103007644 -1.043663264 down T(ph)TSPPLSIPTTHLIHQPAGSR ddPTM_HeLa_Curcumin_4h_R1 2 TTSPPLSIPTTHLIHQPAGSR 21 0 Q5T5U3;A0A087WW76;A0A452Q6Z5;E7ESW5;A0A1B0GV73;Q5T5U3-3 Q5T5U3 ARHGAP21 Rho GTPase-activating protein 21 1 0 T(0.333)T(0.333)S(0.333)PPLS(0.001)IPTTHLIHQPAGSR;T(0.333)T(0.333)S(0.333)PPLSIPTTHLIHQPAGSR ; 107.75 5.03E-05 51776000 2411.9 2296.85 1629.6 1916.17 2413.3 2842.9 1468.79 1002.99 2436 2209.7 TRUE FALSE FALSE 2220.99557 2495.379479 1689.99441 1908.241396 2384.522974 2253.250494 1510.000294 1308.797034 2168.776895 2286.486911 0.97135722 1.091359617 0.739122713 0.834573506 1.042876284 0.985463981 0.660401898 0.572405216 0.94851927 1 11.15891694 -4.702118386 4.417851204 0.96949045 0.595819681 0.654686685 0.097324051 0.08700417 3.35556112 0.013708679 0.054702787 1.99E-05 4.702118386 -0.373670769 RDS(ph)FDDRGPSLNPVLDYDHGSR ddPTM_HeLa_Curcumin_4h_R1 1 RDSFDDRGPSLNPVLDYDHGSR 22 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 1 0 RDS(0.633)FDDRGPS(0.367)LNPVLDYDHGSR 67.785 0.00082849 38389000 1017 745.11 721.04 921.74 1526.5 3630.1 2756.2 5696.6 1471.2 1006 TRUE FALSE FALSE 936.5033769 809.5139883 747.7623767 917.9260841 1508.297484 2877.17634 2833.531554 7433.467116 1309.813041 1040.958425 0.899654928 0.77766217 0.71834029 0.881808593 1.448950744 2.763968542 2.72204104 7.140983671 1.258276036 1 10.02369673 -1.940924794 0.728151954 0.909588506 200 0.960290838 0.372650148 7.900531275 0.15822249 0.054751801 2421.719643 0.011457113 1.940924794 199.0904115 up T(ph)TTLSGTAPAAGVVPSR ddPTM_HeLa_Curcumin_4h_R1 1 TTTLSGTAPAAGVVPSR 17 0 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;P27816-4;B5MEG9;H7C4C5;H0Y2V1;F8W9U4 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 T(0.755)T(0.012)T(0.229)LS(0.004)GTAPAAGVVPSR 149.59 0.00066275 18601000 1483 1321.6 1383.7 1562.7 1624.6 1898.5 1442 1500.2 1691.6 1627.4 TRUE FALSE FALSE 1365.618985 1435.833215 1434.981139 1556.233961 1605.227706 1504.729699 1482.458639 1957.604074 1506.035712 1683.952029 0.810960741 0.85265684 0.852150842 0.924155757 0.953250258 0.893570407 0.880344935 1.162505844 0.894345971 1 10.71763533 -4.258465174 24.76805678 0.902357741 1.162505952 0.70554215 0.05154562 150.7797964 1255562.673 0.010228145 0.095435463 5.51E-05 4.258465174 0.260148211 T(ph)TTPPDSGVLFEGLGISTRPR ddPTM_HeLa_Curcumin_4h_R1 1 TTTPPDSGVLFEGLGISTRPR 21 1 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 0 T(0.342)T(0.342)T(0.24)PPDS(0.076)GVLFEGLGISTRPR 139.39 3.70E-05 27706000 574.71 532.16 472.26 657.03 546.99 847.62 489.8 272.01 737.7 547.64 TRUE FALSE FALSE 529.2210971 578.1575391 489.762371 654.311384 540.4675015 671.8140574 503.5424698 354.9445968 656.7761556 566.6704492 0.933913349 1.0202712 0.864280768 1.154659441 0.953759813 1.185546305 0.888598427 0.626368637 1.159009009 1 9.14636616 -4.335204304 3.687215705 0.98930244 0.611365618 0.541346402 0.108446267 0.118169617 2.696568955 0.01222047 0.104327149 4.62E-05 4.335204304 -0.377936823 T(ph)VASDLQK ddPTM_HeLa_Curcumin_4h_R1 1 TVASDLQK 8 0 Q7L8J4;Q7L8J4-2 Q7L8J4 SH3BP5L SH3 domain-binding protein 5-like 1 0 T(0.998)VAS(0.002)DLQK 142.98 0.0078776 53565000 4029.3 3238.3 3714.1 3784.4 4851.1 5211.3 4887.8 4522.6 4489.9 4622 TRUE FALSE FALSE 3710.376653 3518.204222 3851.747813 3768.741156 4793.253801 4130.417637 5024.938513 5901.519921 3997.369203 4782.614156 0.775805142 0.735623679 0.805364532 0.788008615 1.00222465 0.863631793 1.050667762 1.233952756 0.835812606 1 12.22358369 -4.271660768 1.311959965 0.869355239 1.398960032 0.666824106 0.086240834 0.829332623 1.225163992 0.016351895 0.582938561 5.35E-05 4.271660768 0.529604794 T(ph)VFSPTLPAAR ddPTM_HeLa_Curcumin_4h_R1 3 TVFSPTLPAAR 11 0 Q7Z2W4-2;Q7Z2W4;C9J6P4;Q7Z2W4-3 Q7Z2W4-2 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 0 T(0.973)VFS(0.014)PT(0.013)LPAAR;T(0.988)VFS(0.009)PT(0.003)LPAAR;T(0.562)VFS(0.339)PT(0.099)LPAAR ;; 206.36 6.07E-07 532500000 16099.9 12714.3 13936.7 14518 13755.7 14386.6 10828.9 5227.2 15868.2 12643.5 TRUE FALSE FALSE 14825.57593 13813.26744 14453.20636 14457.92836 13591.67226 11402.65699 11132.72979 6820.949217 14127.49816 13082.86068 1.133205977 1.055829285 1.104743581 1.105104511 1.038891462 0.871572148 0.850940024 0.521365272 1.079847787 1 13.67539041 -3.997369856 0.873962164 1.070601361 1.73E-13 0.927182762 0.047731807 0.752000723 0.312396218 0.009542309 0.857106309 0.000100607 3.997369856 -1.070601361 T(ph)VHRDSEEEDDYLFDDPLPIPLR ddPTM_HeLa_Curcumin_4h_R1 1 TVHRDSEEEDDYLFDDPLPIPLR 23 1 B3KSJ7;Q96SD1-2;Q96SD1-3;Q96SD1 B3KSJ7 DCLRE1C Protein artemis 1 0 T(0.797)VHRDS(0.187)EEEDDY(0.016)LFDDPLPIPLR 45.942 0.014337 2912000 495.26 361.36 541.23 454.9 561.94 455.25 263.21 363.53 548.25 393.27 TRUE FALSE FALSE 456.0596484 392.5943482 561.2884599 453.0177443 555.2392325 360.8260183 270.5949642 474.3686235 488.1083467 406.9361032 1.120715623 0.96475674 1.379303668 1.113240484 1.364438368 0.886689619 0.664956886 1.165707883 1.199471718 1 8.668658471 -3.933099749 22.25155812 1.061808587 4.36861869 0.011744238 0.204658647 4317.919767 1543521.684 0.02683454 52961.30194 0.000116654 3.933099749 3.306810103 T(ph)VQLT(ph)S(ph)S(ph)ELESTLET(ph)LK ddPTM_HeLa_Curcumin_4h_R1 1 TVQLTSSELESTLETLK 17 0 P42704 P42704 LRPPRC "Leucine-rich PPR motif-containing protein, mitochondrial" 5 0 T(0.998)VQLT(0.994)S(0.995)S(0.955)ELES(0.119)T(0.109)LET(0.829)LK 45.579 0.0096185 0 4064.2 2717.2 3194.9 3666.3 3401.4 4705.4 3176.9 3014.9 4010.8 3858.4 TRUE FALSE FALSE 3742.514281 2952.06266 3313.305805 3651.129822 3360.840527 3729.446999 3266.035264 3934.129131 3570.825275 3992.479113 0.937391073 0.739405912 0.829886822 0.914501922 0.841792889 0.934118099 0.818046926 0.985385025 0.894387966 1 11.96306914 -7.492230446 8.559187838 0.972587838 0.864435133 0.191331521 0.069540757 0.205173394 50.9725299 0.011125627 0.012311119 3.22E-08 7.492230446 -0.108152705 T(ph)VRLVT(ph)VPSS(ph)PPT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 TVRLVTVPSSPPTK 14 1 O15072 O15072 ADAMTS3 A disintegrin and metalloproteinase with thrombospondin motifs 3 4 0 T(0.963)VRLVT(0.521)VPS(0.521)S(0.994)PPT(1)K 54.608 0.016339 7461700 1801.2 3104.9 3533.1 3357.6 3620.3 3573.9 3018.8 3070 4899.7 3712.9 TRUE FALSE FALSE 1658.633119 3373.273721 3664.039794 3343.707141 3577.130287 2832.632854 3103.499403 4006.028867 4362.215168 3841.922999 0.431719511 0.878017004 0.953699435 0.870321228 0.931078079 0.737295582 0.80779844 1.042714513 1.135424934 1 11.90761289 -7.057091955 24.99946203 0.727604424 0.883623432 0 0.196945571 498.1083911 218110.9812 0.036595891 0.044820715 8.77E-08 7.057091955 0.156019007 T(ph)VSASSTGDLPK ddPTM_HeLa_Curcumin_4h_R1 2 TVSASSTGDLPK 12 0 P78362;H7C5L6;P78362-2 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 0 T(0.828)VS(0.025)AS(0.146)S(0.001)TGDLPK;T(0.944)VS(0.006)AS(0.014)S(0.036)TGDLPK ; 154.23 0.0010792 22938500 5334.2 4241.43 4448.9 4139.9 4837.8 4580.8 3103.13 3596.19 5168.8 4219.3 TRUE FALSE FALSE 4911.992441 4608.04031 4613.780148 4122.770191 4780.112395 3630.690444 3190.195476 4692.651776 4601.795572 4365.920361 1.125076052 1.055456795 1.056771486 0.944307236 1.094869352 0.831597955 0.730704001 1.074836779 1.054026457 1 12.0920701 -5.259756721 24.988585 1.053117675 0.864212013 0.408024869 0.092115646 99.28250749 1474394.271 0.012940938 0.031209374 5.50E-06 5.259756721 -0.188905662 T(ph)VSDNSLS(ph)NSR ddPTM_HeLa_Curcumin_4h_R1 1 TVSDNSLSNSR 11 0 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 2 0 T(0.914)VS(0.078)DNS(0.036)LS(0.971)NS(0.001)R 128.95 0.013516 38003000 5749 5904 6511.5 5827.3 6893.3 9049 8437.8 3849.7 6518.6 5750 TRUE FALSE FALSE 5293.960584 6414.315452 6752.821918 5803.188177 6811.1019 7172.135397 8674.541959 5023.455808 5803.525889 5949.812072 0.889769378 1.078070261 1.134963901 0.97535655 1.144759165 1.20543898 1.45795226 0.844304954 0.97541331 1 12.53862839 -6.355989053 0.885857893 0.951448759 1.184867488 0.177919148 0.153052043 0.530847233 0.827039267 0.027950404 0.058595236 4.41E-07 6.355989053 0.233418729 T(ph)VSDNSLSNSR ddPTM_HeLa_Curcumin_4h_R1 3 TVSDNSLSNSR 11 0 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 0 T(0.985)VS(0.015)DNSLSNSR;T(0.631)VS(0.228)DNS(0.14)LSNSR;T(0.693)VS(0.069)DNS(0.237)LSNSR ;; 152.38 0.001423 640150000 6602.1 5576.8 6057.6 7136.1 6241.3 7041.9 5533.5 5702.9 5862.4 5327.7 TRUE FALSE FALSE 6079.536818 6058.833742 6282.099985 7106.572709 6166.876574 5581.330561 5688.755117 7441.687957 5219.309387 5512.837178 1.102796368 1.099040938 1.139540273 1.289095339 1.118639346 1.012424344 1.031910599 1.349883502 0.946755585 1 12.42857928 -8.469385243 0.529852042 0.995557648 1.146971227 0.316054041 0.099618309 1.056897441 0.614008016 0.07333176 0.028974164 3.39E-09 8.469385243 0.151413579 T(ph)VSKESLLVSHPSVQTK ddPTM_HeLa_Curcumin_4h_R1 1 TVSKESLLVSHPSVQTK 17 1 Q86TC9;A0A087WX60;Q86TC9-2 Q86TC9 MYPN Myopalladin 1 0 T(0.568)VS(0.428)KES(0.004)LLVSHPSVQTK 127.49 0.00027736 12827000 1722 1372.5 1373.3 1375.1 2024.8 6329.2 2854.3 1371 2782.8 1607.6 TRUE FALSE FALSE 1585.701883 1491.132784 1424.195706 1369.410201 2000.655582 5016.452575 2934.383976 1789.011589 2477.533802 1663.46398 0.953252912 0.896402208 0.856162636 0.823228045 1.202704481 3.015666485 1.764020148 1.075473596 1.489382296 1 10.69997491 -5.503298908 24.70166617 0.953288526 1.962322761 0.443522459 0.474818079 375.6797812 473952.143 0.059945171 0.132218308 3.14E-06 5.503298908 1.009034235 T(ph)VSPPTVCTIPTVVGR ddPTM_HeLa_Curcumin_4h_R1 1 TVSPPTVCTIPTVVGR 16 0 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 0 T(0.996)VS(0.004)PPTVCTIPTVVGR 114.54 0.0084908 0 2002.3 2161.9 2169.8 1666.8 1970.3 2514.8 1783.7 1625.2 2074.3 1916.2 TRUE FALSE FALSE 1843.815842 2348.765003 2250.214697 1659.903223 1946.805459 1993.202132 1833.745821 2120.715998 1846.75448 1982.787807 0.929910823 1.184577086 1.134874185 0.837156259 0.981852648 1.005252365 0.924832105 1.069562759 0.931392897 1 10.95331458 T(ph)VSTSSQPEENVDR ddPTM_HeLa_Curcumin_4h_R1 1 TVSTSSQPEENVDR 14 0 P42684-2;P42684-3;P42684-4;P42684-10;P42684-6;P42684;P42684-7;P42684-5 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 0 T(0.675)VS(0.011)T(0.054)S(0.181)S(0.078)QPEENVDR 133.04 0.0028774 11727000 2179.3 2108.5 2550.4 2514.9 2139.4 2752.9 2272.6 1853.6 2102.8 2077.7 TRUE FALSE FALSE 2006.806105 2290.749345 2644.920068 2504.49401 2113.889052 2181.917508 2336.36304 2418.754107 1872.128101 2149.89992 0.933441639 1.06551441 1.230252647 1.164935161 0.983249979 1.014892595 1.086731069 1.12505428 0.870797791 1 11.07005379 -7.132045625 5.369716914 0.968869776 1.097757247 0.485033529 0.074142983 0.173995259 6.949613537 0.012395783 0.015254072 7.38E-08 7.132045625 0.128887471 T(ph)VTPASSAK ddPTM_HeLa_Curcumin_4h_R1 2 TVTPASSAK 9 0 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 0 T(0.998)VT(0.002)PASSAK;T(1)VTPASSAK ; 134.84 0.0091537 584810000 18734.7 24431 20594 15612.3 18221.1 18534.1 15055.2 9923.1 15615.9 18879.4 TRUE FALSE FALSE 17251.82873 26542.70678 21357.23176 15547.70044 18003.82528 14689.91874 15477.60839 12948.60751 13902.87484 19535.45774 0.883103378 1.358693875 1.093254739 0.795870803 0.921597309 0.751961839 0.792282863 0.662825908 0.711673871 1 14.25380744 -5.460088113 1.306187233 0.98519989 0.722451488 0.308791171 0.165130043 0.423156918 1.368799597 0.02378567 0.081386766 3.47E-06 5.460088113 -0.262748402 T(ph)VTPASSAKT(ph)SPAK ddPTM_HeLa_Curcumin_4h_R1 1 TVTPASSAKTSPAK 14 1 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 2 0 T(0.953)VT(0.047)PASSAKT(0.773)S(0.227)PAK 157.07 0.0003214 15182000 5250.9 4285.5 3353.8 4277.9 2800.9 4620 3363.1 2580.8 6055.6 4765.8 TRUE FALSE FALSE 4835.285724 4655.919524 3478.094778 4260.199183 2767.501097 3661.759922 3457.459535 3367.674039 5391.31583 4931.411195 0.980507513 0.944135328 0.70529401 0.86389048 0.561198608 0.742537942 0.70110956 0.682902704 1.093260249 1 12.26778484 -6.744060995 1.380737001 0.99470216 0.694078377 0.769899936 0.078627248 0.120610172 0.463810141 0.011614022 0.017373901 1.80E-07 6.744060995 -0.300623782 T(ph)Y(ph)VDEVNSELVNIYT(ph)FNHTVTR ddPTM_HeLa_Curcumin_4h_R1 1 TYVDEVNSELVNIYTFNHTVTR 22 0 E9PMC3;F5H8L4;C9JBG5;Q8NBJ9;Q8NBJ9-2 E9PMC3 SIDT2 SID1 transmembrane family member 2 3 0 T(0.984)Y(0.974)VDEVNS(0.042)ELVNIYT(0.473)FNHT(0.294)VT(0.233)R 57.629 0.0037864 9768800 1492.5 1391.3 1209.4 1224.2 2613.2 3201.2 1355.3 693.04 2302.1 1597.2 TRUE FALSE FALSE 1374.36705 1511.557772 1254.221428 1219.134585 2582.039297 2537.235035 1393.32607 904.3447056 2049.56539 1652.702581 0.831587647 0.914597575 0.75889119 0.737661209 1.562313344 1.53520365 0.843059172 0.54719144 1.240129599 1 10.69061141 T(ph)YGGDTGSPEISFTK ddPTM_HeLa_Curcumin_4h_R1 1 TYGGDTGSPEISFTK 15 0 O94915;H0Y9X0;A0A286YEZ9;A0A2C9F2R7 O94915 FRYL Protein furry homolog-like 1 0 T(0.795)Y(0.018)GGDT(0.172)GS(0.014)PEISFTK 104.07 0.0082789 8660200 2673.8 2072.2 1976.9 2741.6 2192.1 3507.6 3198.3 3380.9 2870.7 2820.8 TRUE FALSE FALSE 2462.165909 2251.311734 2050.165653 2730.255986 2165.960639 2780.084221 3288.03569 4411.720846 2555.791392 2918.82259 0.84354764 0.771308178 0.702394746 0.935396346 0.74206656 0.952467694 1.126493848 1.511472763 0.875624096 1 11.51117081 -4.345930378 1.809325331 0.884860747 1.650350481 0.828199482 0.092895922 0.266899889 0.999649271 0.016023608 0.326640178 4.51E-05 4.345930378 0.765489733 T(ph)YGGS(ph)YGGRGRGRR ddPTM_HeLa_Curcumin_4h_R1 1 TYGGSYGGRGRGRR 14 3 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 2 0 T(0.768)Y(0.233)GGS(0.94)Y(0.059)GGRGRGRR 92.939 0.012706 13769000 1135.5 1087.8 896.97 1031.7 930.12 901.51 968.3 456.42 1033 970.81 TRUE FALSE FALSE 1045.623977 1181.824585 930.2124973 1027.431099 919.0289265 714.5266639 995.467892 595.5803569 919.6824844 1004.545575 1.040892522 1.176476821 0.92600328 1.022781966 0.914870315 0.711293426 0.990963393 0.592885352 0.915520915 1 9.972327304 -5.541745406 2.983192108 1.025572388 0.786992418 0.477557713 0.114786614 0.150720615 2.731505067 0.014516215 0.03293796 2.87E-06 5.541745406 -0.238579971 T(ph)YGGSY(ph)GGRGRGRR ddPTM_HeLa_Curcumin_4h_R1 1 TYGGSYGGRGRGRR 14 3 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 2 0 T(0.904)Y(0.096)GGS(0.532)Y(0.468)GGRGRGRR 78.705 0.0093039 12384000 2207.9 2045.5 1845.4 2080 2251.2 2754.9 1503.8 1184.3 2323.5 2109.4 TRUE FALSE FALSE 2033.142385 2222.303905 1913.792147 2071.393511 2224.35591 2183.502686 1545.992581 1545.387618 2068.617863 2182.701493 0.931479816 1.01814376 0.876799761 0.949004487 1.019083882 1.000367065 0.70829318 0.708016017 0.94773283 1 11.09189913 -4.757102305 24.99882541 0.968211888 0.70815447 0.859612484 0.041975447 27.68141946 159548.8967 0.006114996 0.021379257 1.75E-05 4.757102305 -0.260057417 T(ph)YSDEANQMR ddPTM_HeLa_Curcumin_4h_R1 3 TYSDEANQMR 10 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 0 T(0.721)YS(0.279)DEANQMR;T(0.796)YS(0.204)DEANQMR;T(0.656)YS(0.344)DEANQMR ;; 182.41 0.0007538 239578000 6665.6 5181.5 5733.3 5802.1 5610.6 6980.7 5474.7 3614.5 7439.6 5930.5 TRUE FALSE FALSE 6138.010726 5629.365772 5945.781142 5778.092448 5543.697259 5532.824131 5628.305348 4716.544411 6623.494493 6136.584434 1.000232425 0.917345118 0.968907249 0.941581186 0.903384826 0.901612972 0.917172314 0.768594397 1.079345451 1 12.58322017 -1.675349731 0.270545511 1.007355459 1.60E-11 0.752844423 0.038736483 9.997869958 0.176276162 0.013893604 4.436319081 0.021117878 1.675349731 -1.007355459 T(ph)YT(ph)LFEY(ph)AK ddPTM_HeLa_Curcumin_4h_R1 1 TYTLFEYAK 9 0 Q6NW29-2 Q6NW29-2 3 0 T(0.811)Y(0.522)T(0.668)LFEY(0.999)AK 67.207 0.0082402 0 1694.2 1078 1118.9 1769.6 1580.8 406.34 478.03 665.14 1293.8 1258.2 TRUE FALSE FALSE 1560.102282 1171.177517 1160.367418 1762.277864 1561.949992 322.0605036 491.4422352 867.9381241 1151.873377 1301.922356 1.1983067 0.899575548 0.891272366 1.353596745 1.199725917 0.24737305 0.377474304 0.666658899 0.884748135 1 10.3464277 -5.265072018 24.99596932 1.09127841 0.425199292 0.726433091 0.176626281 107.6474903 740718.5254 0.0243462 0.056498019 5.43E-06 5.265072018 -0.666079118 T(ph)YVIAASTMSVCSSDVGHVSR ddPTM_HeLa_Curcumin_4h_R1 1 TYVIAASTMSVCSSDVGHVSR 21 0 P60410 P60410 KRTAP10-8 Keratin-associated protein 10-8 1 0 T(0.991)Y(0.009)VIAASTMSVCSSDVGHVSR 95.073 0.00043936 0 1836 1429.2 1491.7 1807.7 1113 2100.5 1334.7 580.56 1766.6 1595.2 TRUE FALSE FALSE 1690.678663 1552.73368 1546.983714 1800.220216 1099.728202 1664.832622 1372.14809 757.5700714 1572.8084 1650.633081 1.024260741 0.940689786 0.937206295 1.090624099 0.666246311 1.008602482 0.83128595 0.458957281 0.952851617 1 10.68880374 -3.980933992 0.999198978 0.992340752 1.80E-69 0.623578244 0.111873372 1.349751361 0.717812061 0.015955538 1.634876641 0.000104488 3.980933992 -0.992340752 T(ph)YVS(ph)KLNAET(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 TYVSKLNAETSR 12 1 Q86Y13 Q86Y13 DZIP3 E3 ubiquitin-protein ligase DZIP3 3 0 T(0.675)Y(0.469)VS(0.856)KLNAET(0.704)S(0.296)R 82.483 0.0095561 0 441.6 416.82 453.18 376.35 418.07 618.54 543.41 445.54 274.35 367.97 TRUE FALSE FALSE 406.646894 452.8480635 469.9752495 374.7927634 413.0847883 490.2478316 558.6566221 581.383095 244.2544914 380.7569301 1.067996041 1.189336366 1.234318307 0.984336026 1.084904189 1.287561152 1.467226406 1.52691402 0.641497165 1 8.572726485 -1.000000001 0.360895934 1.027753389 8.136830268 0.616852093 0.150318017 18.3696698 0.227829149 0.025480881 90.93821906 0.1 1.000000001 7.109076879 TAAAASEK(ac)NR ddPTM_HeLa_Curcumin_4h_R1 2 TAAAASEKNR 10 1 K7EN09;Q9UNZ5 K7EN09 C19orf53 Leydig cell tumor 10 kDa protein homolog 0 1 ; TAAAASEK(1)NR;TAAAASEK(1)NR 154.85 1.32E-08 6476500 2170.67 1711.25 2249 1593.12 2034.6 2623.1 1777.77 1830.29 1835.22 1985.63 FALSE TRUE FALSE 1998.859179 1859.162825 2332.349918 1586.528092 2010.338724 2079.039492 1827.649442 2388.336995 1633.900957 2054.630495 0.972855793 0.904864806 1.135167576 0.772171977 0.978442951 1.011879993 0.889527069 1.162416795 0.795228612 1 11.00466325 -4.244348011 24.12263104 0.973168246 1.162417043 0.235798848 0.10593086 1971.220281 2782095.054 0.011043528 0.40886421 5.70E-05 4.244348011 0.189248796 TAAAASEK(ac)NRGPR ddPTM_HeLa_Curcumin_4h_R1 1 TAAAASEKNRGPR 13 2 K7EN09;Q9UNZ5 K7EN09 C19orf53 Leydig cell tumor 10 kDa protein homolog 0 1 TAAAASEK(1)NRGPR 79.744 0.0085017 886160 403.59 333.18 548.29 375.61 153.11 381.27 140.4 310.74 452.46 557.5 FALSE TRUE FALSE 371.6454256 361.9785946 568.6101097 374.0558253 151.2842632 302.1903042 144.3392461 405.4831955 402.82627 576.8730835 0.644241231 0.627483939 0.985676271 0.64841962 0.262248782 0.523841921 0.250209709 0.702898449 0.698292712 1 9.17211014 -5.983205268 6.69474911 0.819717173 0.429705676 0.492588035 0.169242979 0.100651896 19.098575 0.027559914 0.049417045 1.04E-06 5.983205268 -0.390011497 TAADVVS(ph)PGANSVDSR ddPTM_HeLa_Curcumin_4h_R1 1 TAADVVSPGANSVDSR 16 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 0 TAADVVS(0.795)PGANS(0.205)VDS(0.001)R 108.25 0.0017597 104220000 3397.4 2964.9 3443.3 3446.9 2979.8 3847.2 3001.3 3441.9 3650.1 2846.7 TRUE FALSE FALSE 3128.492205 3221.172745 3570.911727 3432.637641 2944.267831 3049.247353 3085.5084 4491.319465 3249.693162 2945.622613 1.062081813 1.093545633 1.212277401 1.165335174 0.999540069 1.035179232 1.047489379 1.524743681 1.103227938 1 11.52435689 -4.26090171 24.86483656 1.054724176 1.524743833 0.78423607 0.068881084 14.58026101 674078.7658 0.010598612 0.084520397 5.48E-05 4.26090171 0.470019658 TAADVVSPGANS(ph)VDSR ddPTM_HeLa_Curcumin_4h_R1 1 TAADVVSPGANSVDSR 16 0 Q01804-5;Q01804-3;Q01804 Q01804-5 OTUD4 OTU domain-containing protein 4 1 0 TAADVVS(0.145)PGANS(0.855)VDSR 270.79 3.26E-52 102950000 3048.2 2729 2533 2779.4 2720.5 3370.4 2429.7 3365.1 2841 2641 TRUE FALSE FALSE 2806.931754 2964.8826 2626.875208 2767.899579 2688.059814 2671.341048 2497.870843 4391.103499 2529.349408 2732.774553 1.02713623 1.084934941 0.961248415 1.012853247 0.983637604 0.977519732 0.914042046 1.606829767 0.925560949 1 11.41615073 -4.256134935 24.99994059 1.005189232 1.606830019 0.932632723 0.04973538 87.3612802 411722.2342 0.005840547 0.066741516 5.54E-05 4.256134935 0.601640787 SVEDEMDS(ph)PGEEPFYTGQGR ddPTM_HeLa_Curcumin_4h_R1 4 SVEDEMDSPGEEPFYTGQGR 20 0 A0A590UJA3;S4R3W2;A0A590UJU2;A0A590UK38;A0A590UK73;B1AKN7;B1AKN5;A0A590UK09;B1AKN8;Q12857-2;Q12857-3;Q12857;Q12857-4 A0A590UJA3 NFIA Nuclear factor 1;Nuclear factor 1 A-type 1 0 SVEDEMDS(1)PGEEPFYTGQGR;SVEDEMDS(1)PGEEPFYTGQGR;SVEDEMDS(1)PGEEPFYTGQGR;S(0.007)VEDEMDS(0.993)PGEEPFYTGQGR ;;; 409.01 0 224451000 19058.3 15664.2 17535.9 17993.7 18329.6 19121.6 14194.7 5281.12 17498 15204.4 TRUE FALSE FALSE 17549.81544 17018.14365 18185.79588 17919.24684 18111.03149 15155.56462 14592.96508 6891.309177 15578.51318 15732.75177 1.115495605 1.081701657 1.155919584 1.138977281 1.151167435 0.96331302 0.927553253 0.43802313 0.990196337 1 13.94148341 -4.099902899 1.541485404 1.075500339 6.15E-13 0.903802197 0.062714655 0.386894774 0.623627161 0.010007421 0.704208998 7.95E-05 4.099902899 -1.075500339 down TAAK(ac)LSTSAK ddPTM_HeLa_Curcumin_4h_R1 2 TAAKLSTSAK 10 1 F8WF15;F8W8F0;C9J180;Q96LR5 F8WF15 UBE2E2 Ubiquitin-conjugating enzyme E2 E2 0 1 ; TAAK(1)LSTSAK;TAAK(1)LSTSAK 133.07 0.0010176 4336700 2535.8 2204.9 2525.6 1979.42 2615.4 3395.9 3078.8 2607.8 2413.9 2528.8 FALSE TRUE FALSE 2335.088754 2395.481731 2619.200958 1971.229685 2584.213063 2691.55206 3165.182842 3402.906215 2149.101209 2616.675612 0.892387556 0.915467596 1.000965097 0.75333361 0.987593973 1.028615105 1.209619881 1.300469267 0.821309756 1 11.35351937 -4.761911409 1.825022971 0.936581236 1.306181547 0.757525579 0.077214101 0.14677896 0.86585813 0.010472937 0.066518645 1.73E-05 4.761911409 0.369600311 TAAK(ac)SQSSTSTTGAK ddPTM_HeLa_Curcumin_4h_R1 2 TAAKSQSSTSTTGAK 15 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 0 1 ; TAAK(1)SQSSTSTTGAK;TAAK(1)SQSSTSTTGAK 293.8 3.48E-112 1403660 179.09 80.347 198.58 347.41 314.98 395.732 331.18 232.63 402.28 175.85 FALSE TRUE FALSE 164.9148375 87.29183666 205.9395495 345.9725095 311.2240692 313.6527224 340.4720195 303.5578161 358.1508905 181.9607744 0.906320816 0.47972887 1.131779913 1.901357645 1.710390991 1.723738116 1.871128657 1.66825964 1.968286251 1 7.50748367 -6.374718335 4.475644523 0.914826757 1.772205189 0.42831468 0.36878028 0.057619831 1.884363567 0.02505626 0.038756136 4.22E-07 6.374718335 0.857378432 TAAKGEAAAERPGEAAVAS(ph)SPSK ddPTM_HeLa_Curcumin_4h_R1 2 TAAKGEAAAERPGEAAVASSPSK 23 2 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 TAAKGEAAAERPGEAAVAS(0.975)S(0.02)PS(0.005)K;TAAKGEAAAERPGEAAVAS(0.762)S(0.204)PS(0.033)K ; 74.214 0.00084101 179646000 11134.4 8794.6 8962.1 9622.1 7647.7 12207.9 7663.5 5422.6 11773.8 10630.9 TRUE FALSE FALSE 10253.10049 9554.766036 9294.24331 9582.2863 7556.506172 9675.843929 7878.517185 7075.925777 10482.2436 11000.32298 0.932072677 0.868589591 0.844906402 0.871091359 0.686934937 0.879596348 0.716207806 0.643247093 0.952903257 1 13.42525826 -2.405839619 0.164634958 1.045687736 8.09E-11 0.742985003 0.0572813 11.83223672 0.185126711 0.095760752 2.791670852 0.0039279 2.405839619 -1.045687736 TAAPSVRPEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 TAAPSVRPEKR 11 2 Q14137;A0A075B729 Q14137 BOP1 Ribosome biogenesis protein BOP1 0 1 TAAPSVRPEK(1)R 91.123 0.0044925 4249900 1682.3 1314.6 1164.3 1435.1 1356.7 2158 2029.4 1597.6 1732.8 1437 FALSE TRUE FALSE 1549.14418 1428.228166 1207.449982 1429.161936 1340.522239 1710.406474 2086.339502 2084.700886 1542.716175 1486.935643 1.041836738 0.960517809 0.812039168 0.961145792 0.901533462 1.150289511 1.403113519 1.40201151 1.03751375 1 10.53812649 -4.908629277 3.127086919 0.988649905 1.407960552 0.86592516 0.06880165 0.071992104 1.39200632 0.011001583 0.039224048 1.23E-05 4.908629277 0.419310648 TAATS(ph)VPAYEPLDSLDR ddPTM_HeLa_Curcumin_4h_R1 1 TAATSVPAYEPLDSLDR 17 0 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 0 TAAT(0.053)S(0.946)VPAYEPLDSLDR 120.54 0.00062169 2502500 737.72 747.24 505.61 500.42 709.9 885.7 433.85 511.51 764.76 634.02 TRUE FALSE FALSE 679.3286836 811.828096 524.3483514 498.3493946 701.4349062 701.9958361 446.0226634 667.4670443 680.8677413 656.0521478 1.035479704 1.23744446 0.799247976 0.75961857 1.069175535 1.070030543 0.679858552 1.017399374 1.037825642 1 9.357666685 -6.725821981 24.99999762 1.033774513 0.898394369 0.263305773 0.138663523 227.523956 159699.5507 0.021377929 0.030232335 1.88E-07 6.725821981 -0.135380144 VAPGPSSGSTPGQVPGS(ph)SALSSPRR ddPTM_HeLa_Curcumin_4h_R1 1 VAPGPSSGSTPGQVPGSSALSSPRR 25 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-5 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 VAPGPSSGSTPGQVPGS(0.25)S(0.25)ALS(0.25)S(0.25)PRR 69.272 0.00037995 30444000 3005.9 2259.4 2562.4 2354.7 2486.7 2815.9 1771.9 882.82 2910.7 2436.7 TRUE FALSE FALSE 2767.979843 2454.692468 2657.364798 2344.956875 2457.047727 2231.850598 1821.614745 1151.987754 2591.403492 2521.375144 1.097805636 0.973553053 1.053934717 0.930030932 0.974487169 0.885171968 0.722468749 0.456888677 1.027773871 1 11.29999507 -4.0985967 0.770609671 1.039175471 2.65E-13 0.949701257 0.040593128 0.526606947 0.188614924 0.007779856 0.497514579 7.97E-05 4.0985967 -1.039175471 down EVS(ph)PAPAVAGQSK ddPTM_HeLa_Curcumin_4h_R1 1 EVSPAPAVAGQSK 13 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 0 EVS(1)PAPAVAGQSK 124.42 0.0020994 47077000 4348 4055.7 4032.9 3720 4093.3 3921.8 3103.1 1277.4 4244.6 3983.4 TRUE FALSE FALSE 4003.851212 4406.256636 4182.362822 3704.607626 4044.490071 3108.374472 3190.164634 1666.87338 3778.977999 4121.822854 0.97137877 1.069006795 1.014687669 0.898778952 0.981238208 0.754126168 0.773969369 0.404401994 0.916822031 1 12.00906679 -4.097275203 0.806113213 0.993094695 6.45E-19 0.887777914 0.061935974 0.58430803 0.229744573 0.008441349 0.550194711 7.99E-05 4.097275203 -0.993094695 down TADSVS(ph)PLEPPTK ddPTM_HeLa_Curcumin_4h_R1 1 TADSVSPLEPPTK 13 0 Q9UMZ2-6;Q9UMZ2-9;Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2 Q9UMZ2-6 SYNRG Synergin gamma 1 0 TADS(0.008)VS(0.991)PLEPPTK 123.95 0.0019711 0 2199.2 1827.8 2071.2 2316.4 2523.5 2548.3 1988.7 6632.1 2163.7 1951.3 TRUE FALSE FALSE 2025.130999 1985.786887 2147.960494 2306.815351 2493.408911 2019.753855 2044.49757 8654.19676 1926.347523 2019.10753 1.002983234 0.983497341 1.063816792 1.14249257 1.234906449 1.000320104 1.012574882 4.286149515 0.954058907 1 10.97950203 -4.261254942 24.99996747 1.029859234 4.286150478 0.99301242 0.081586821 0.848664169 114945.7464 0.011849908 0.091872416 5.48E-05 4.261254942 3.256291244 TADSVS(ph)PLEPPTKDK ddPTM_HeLa_Curcumin_4h_R1 2 TADSVSPLEPPTKDK 15 1 Q9UMZ2-6;Q9UMZ2-9;Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2 Q9UMZ2-6 SYNRG Synergin gamma 1 0 T(0.065)ADS(0.387)VS(0.548)PLEPPTKDK;T(0.008)ADS(0.093)VS(0.899)PLEPPTKDK ; 122.5 0.00049613 30304000 5699.7 5350.7 5172.9 5319.1 5298.1 6558.2 5790.2 15265.8 5990.5 5944.4 TRUE FALSE FALSE 5248.562731 5813.190666 5364.612225 5297.090974 5234.923618 5197.955394 5952.657428 19920.27214 5333.357137 6150.967458 0.853290603 0.945085583 0.872157471 0.861180133 0.85107321 0.845063062 0.967759539 3.238559183 0.867076143 1 12.58659763 -4.261486757 6.181770957 0.910732518 3.294849377 0.994729395 0.05116484 0.007862051 1.560829344 0.00921395 0.078259112 5.48E-05 4.261486757 2.38411686 NGSGTLTGSHDYPAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 NGSGTLTGSHDYPAKK 16 1 Q7Z7F0 Q7Z7F0 KIAA0907 UPF0469 protein KIAA0907 0 1 NGSGTLTGSHDYPAK(1)K 99.711 0.0017759 6677700 4074.4 3876.5 3594 3147.7 3905.5 7130.8 4556 6277.9 4759 3471 FALSE TRUE FALSE 3751.906941 4211.567387 3727.196802 3134.675651 3858.929463 5651.791699 4683.829098 8192.00281 4236.949606 3591.616992 1.044628909 1.172610386 1.037748961 0.872775593 1.074426776 1.57360646 1.304100384 2.280867595 1.179677459 1 11.81041779 -1 0.692262186 1.023706922 146.1929263 0.838235204 0.155976792 61.43587814 0.313721334 0.023025051 13806.54786 0.1 1 145.1692194 up TAENATSGET(ph)LEENEAGD ddPTM_HeLa_Curcumin_4h_R1 1 TAENATSGETLEENEAGD 18 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 1 0 TAENATS(0.001)GET(0.999)LEENEAGD 86.222 0.012179 2648400 1653.8 1445 1573.6 1463.4 1475.1 1711.6 1620.3 936.31 1701.2 1352.5 TRUE FALSE FALSE 1522.899985 1569.899361 1631.919 1457.344839 1457.510396 1356.594866 1665.761257 1221.786609 1514.582616 1399.499274 1.088174901 1.121757896 1.166073488 1.041333043 1.041451341 0.969343029 1.190255178 0.873016965 1.082231798 1 10.45069502 -4.229283807 23.9170399 1.058629146 0.873016357 0.426585244 0.068035725 6760.171154 5028007.94 0.009666613 1.843998125 5.90E-05 4.229283807 -0.18561279 TAENATSGETLEENEAGD ddPTM_HeLa_Curcumin_4h_R1 2 TAENATSGETLEENEAGD 18 0 Q9UQ80;Q9UQ80-2 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 0 ; ; 213.99 6.13E-16 313390000 26603 21945.9 23203 24030 23250 29223 22794.9 23486 26803 23036 FALSE FALSE TRUE 24497.34448 23842.80581 24062.92359 23930.57023 22972.75894 23161.82039 23434.46354 30646.77328 23862.77796 23836.49929 1.027724088 1.000264574 1.009499059 1.003946508 0.96376396 0.971695554 0.983133608 1.28570781 1.001102455 1 14.54088475 -4.258849739 24.99952583 1.004085215 1.285707909 0.95251677 0.019344702 42.78416368 412999.8001 0.003249199 0.029395612 5.51E-05 4.258849739 0.281622694 TAENFR ddPTM_HeLa_Curcumin_4h_R1 1 TAENFR 6 0 P49792;C9JQD4;R4GN99;H0Y548;P30405;A6NM32;O43447;P30405-2;P62937;F8WE65;C9J5S7;P0DN26;A0A0H2UH34;A0A0B4J2A2;A0A075B767;A0A075B759;Q9Y536;F5H284;P0DN37;Q08752 P49792;P62937;Q08752 RANBP2;PPIH;PPIF;PPIA;PPIAL4C;PPIAL4E;PPIAL4A;PPIAL4D;PPID "E3 SUMO-protein ligase RanBP2;Peptidyl-prolyl cis-trans isomerase;Peptidyl-prolyl cis-trans isomerase F, mitochondrial;Peptidyl-prolyl cis-trans isomerase H;Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase A-like 4A/B/C;Peptidyl-prolyl cis-trans isomerase A-like 4D;Peptidyl-prolyl cis-trans isomerase D" 0 0 143.37 0.0032666 50231000 9348.6 9456.2 7882.1 6648.9 6468.3 10057 6922.9 7870.5 6664.1 8207.8 FALSE FALSE TRUE 8608.648445 10273.55179 8174.21756 6621.388614 6391.169747 7971.064834 7117.137942 10270.17922 5933.064903 8493.020439 1.013614474 1.209646423 0.962462956 0.779627067 0.752520236 0.938542994 0.837998447 1.209249323 0.698581258 1 13.05206201 -6.520595535 24.99926771 1.024907359 0.891248288 0.017652126 0.16711281 112.9328281 1236524.336 0.020007175 0.028569456 3.02E-07 6.520595535 -0.133659071 QGSPDQVS(ph)PVSEMTSTSLYQDK ddPTM_HeLa_Curcumin_4h_R1 2 QGSPDQVSPVSEMTSTSLYQDK 22 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 QGS(0.076)PDQVS(0.923)PVS(0.001)EMTSTSLYQDK;QGS(0.04)PDQVS(0.958)PVS(0.001)EMTSTSLYQDK ; 84.515 0.0003821 7152300 2918.1 2676.4 2579.6 2567.62 3312 4127.8 3813.1 6184.9 2735.2 2349.5 TRUE FALSE FALSE 2687.129306 2907.73609 2675.202245 2556.995869 3272.506563 3271.64775 3920.085324 8070.647538 2435.155403 2431.14495 1.105293745 1.196035674 1.100387801 1.051766111 1.346076285 1.345723031 1.612444097 3.319689983 1.001649615 1 11.2474202 -1.917415962 0.932449273 1.074569528 200 0.976594596 0.101408723 15.55431351 0.19367847 0.016216932 6396.098939 0.012094392 1.917415962 198.9254304 up TAFITNFT(ph)LTIDGVTY(ph)PGNVK ddPTM_HeLa_Curcumin_4h_R1 1 TAFITNFTLTIDGVTYPGNVK 21 0 A0A087WW43;E7ET33;Q06033-2;Q06033 A0A087WW43 ITIH3 Inter-alpha-trypsin inhibitor heavy chain H3 2 0 T(0.134)AFIT(0.139)NFT(0.703)LT(0.025)IDGVT(0.129)Y(0.871)PGNVK 52.162 0.012782 37609000 2698 2216.3 2763.3 2846.4 2683.5 2904.4 2117.4 2192.3 2584 2225.8 TRUE FALSE FALSE 2484.450453 2407.867096 2865.710329 2834.622351 2651.501015 2301.994701 2176.808545 2860.722178 2300.541665 2303.146384 1.078720167 1.045468544 1.244258875 1.230760828 1.151251624 0.999499952 0.945145545 1.242093076 0.99886906 1 11.16939039 -8.127044483 0.86262517 1.012842248 1.118638372 0.195699476 0.097441756 0.723206213 1.154597782 0.033506857 0.023300328 7.46E-09 8.127044483 0.105796124 TAFYNEDDS(ph)EEEQR ddPTM_HeLa_Curcumin_4h_R1 4 TAFYNEDDSEEEQR 14 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 0 TAFYNEDDS(1)EEEQR;TAFYNEDDS(1)EEEQR;TAFYNEDDS(1)EEEQR;TAFYNEDDS(1)EEEQR ;;; 285.18 6.48E-64 197982000 7914 5522.9 7206 7340.7 8831.5 7963.8 6189.1 4794.3 6450 5431 TRUE FALSE FALSE 7287.598549 6000.274866 7473.060699 7310.326128 8726.190131 6312.018109 6362.749489 6256.06 5742.451137 5619.726846 1.29678875 1.067716462 1.329790736 1.300832999 1.552778341 1.123189486 1.132216861 1.113232043 1.021838124 1 12.45628429 -9.380788219 0.835998788 0.98103808 1.247084103 0.310266444 0.135887377 0.756666692 0.832999444 0.137388316 0.026741873 4.16E-10 9.380788219 0.266046023 TAGPIAS(ph)AQKQPAGK ddPTM_HeLa_Curcumin_4h_R1 1 TAGPIASAQKQPAGK 15 1 E7EVA0;P27816;P27816-6;P27816-2;P27816-4;B5MEG9 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 TAGPIAS(1)AQKQPAGK 79.347 0.0071515 14751000 2080.3 1496.4 2105.2 2597.6 1729.7 4120.6 4675.1 1859.2 2385.7 1794 TRUE FALSE FALSE 1915.64206 1625.742148 2183.220564 2586.851819 1709.074457 3265.941111 4806.270724 2426.061521 2123.994679 1856.341366 1.031944929 0.875777579 1.17608787 1.393521615 0.920668196 1.759342958 2.589109315 1.306904843 1.14418324 1 10.85824632 -5.159977299 4.477472552 1.041043175 1.993455885 0.568627484 0.321963196 0.097551894 3.271203024 0.040282255 0.107542326 6.92E-06 5.159977299 0.952412709 TAGPIASAQK(ac)QPAGK ddPTM_HeLa_Curcumin_4h_R1 1 TAGPIASAQKQPAGK 15 1 E7EVA0;P27816;P27816-6;P27816-2;P27816-4;B5MEG9 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 0 1 TAGPIASAQK(1)QPAGK 126.32 0.0012668 4322600 308.91 277.36 261.23 294.59 260.38 411.3 385.85 352.95 509.56 335.66 FALSE TRUE FALSE 284.4594475 301.3337625 270.9114136 293.3710646 257.2751386 325.9917437 396.6759125 460.5628302 453.6625429 347.32416 0.819002765 0.867586529 0.779995879 0.84466069 0.740734933 0.938580673 1.142091332 1.326031654 1.306164659 1 8.440138958 -4.606436716 2.372096791 0.882077221 1.318989731 0.433874402 0.15207496 0.137521852 1.382357217 0.013553714 0.090815055 2.47E-05 4.606436716 0.43691251 TAHNS(ph)EADLEES(ph)FNEHELEPSSPK ddPTM_HeLa_Curcumin_4h_R1 1 TAHNSEADLEESFNEHELEPSSPK 24 0 Q8IWS0-5;Q8IWS0 Q8IWS0-5 PHF6 PHD finger protein 6 2 0 T(0.05)AHNS(0.95)EADLEES(0.764)FNEHELEPS(0.096)S(0.14)PK 68.134 0.00051731 4886300 1927.6 1538.1 1458.8 1948.6 1833.8 2261.1 1597 2411.4 2234.4 2324.7 TRUE FALSE FALSE 1775.028426 1671.04651 1512.864411 1940.53721 1811.933133 1792.122372 1641.807522 3146.624759 1989.29191 2405.483152 0.737909315 0.694682276 0.628923304 0.806714114 0.753251226 0.745015558 0.682527134 1.308105092 0.826982267 1 11.23211098 -2.833984041 14.65861721 0.835174022 43.85055662 0 0.19015445 0 0 0.025655057 0 0.001465602 2.833984041 43.0153826 TAHNS(ph)EADLEESFNEHELEPSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 TAHNSEADLEESFNEHELEPSSPK 24 0 Q8IWS0-5;Q8IWS0 Q8IWS0-5 PHF6 PHD finger protein 6 2 0 T(0.025)AHNS(0.797)EADLEES(0.179)FNEHELEPS(0.194)S(0.805)PK 79.829 0.00055502 6331900 1390 1154.9 1561.1 1263.2 1821.9 1713 1696.4 1799.1 1676.3 1647.2 TRUE FALSE FALSE 1279.980033 1254.72441 1618.955739 1257.973213 1800.175032 1357.704491 1743.996418 2347.637308 1492.414084 1704.440077 0.750968045 0.736150497 0.949846088 0.738056579 1.056167979 0.796569213 1.023207821 1.377365704 0.875603727 1 10.73508216 -4.319413035 2.571965007 0.8718348 1.44994836 0.678452479 0.107181682 0.213804332 1.953818082 0.016983072 0.250968875 4.79E-05 4.319413035 0.578113561 TAHNSEAADLEES(ph)FNEHELEPSSPK ddPTM_HeLa_Curcumin_4h_R1 1 TAHNSEAADLEESFNEHELEPSSPK 25 0 A0A0D9SGE8;Q5JRC6;Q8IWS0-2 A0A0D9SGE8 PHF6 PHD finger protein 6 1 0 TAHNSEAADLEES(0.948)FNEHELEPS(0.015)S(0.037)PK 75.225 0.00014297 12191000 2430.7 2059.9 2018.2 2128.5 2384.5 3547.4 2236 1964.7 2765.6 1996.1 TRUE FALSE FALSE 2238.30753 2237.948577 2092.996267 2119.692831 2356.066395 2811.629253 2298.736142 2563.727986 2462.220599 2065.464326 1.083682493 1.083508705 1.013329662 1.026254873 1.140695758 1.361257717 1.112939165 1.241235664 1.192090596 1 11.01225043 -5.558592347 4.737492134 1.041731844 1.230160315 0.477979525 0.077646597 0.087024538 4.615294733 0.008971489 0.018757444 2.76E-06 5.558592347 0.188428471 TAHNSEADLEES(ph)FNEHELEPSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 TAHNSEADLEESFNEHELEPSSPK 24 0 Q8IWS0-5;Q8IWS0 Q8IWS0-5 PHF6 PHD finger protein 6 2 0 TAHNSEADLEES(0.998)FNEHELEPS(0.325)S(0.677)PK 58.021 0.0032297 8225700 2878.6 2378.2 2428.1 2518 3277.3 5256.1 3084.4 1141.1 3302.6 2792 TRUE FALSE FALSE 2650.755773 2583.761011 2518.087522 2507.581183 3238.220338 4165.925612 3170.939963 1489.016137 2940.313043 2889.021792 0.917527095 0.894337667 0.871605582 0.86796894 1.120870859 1.441984835 1.09758257 0.515404952 1.017753847 1 11.49636537 -5.753924088 24.96580786 0.941315989 1.076221225 0.053931889 0.217496346 356.7332408 1185057.966 0.031086431 0.061212911 1.76E-06 5.753924088 0.134905235 TAHNSEADLEESFNEHELEPSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 TAHNSEADLEESFNEHELEPSSPK 24 0 Q8IWS0-5;Q8IWS0 Q8IWS0-5 PHF6 PHD finger protein 6 1 0 TAHNSEADLEES(0.001)FNEHELEPS(0.065)S(0.934)PK;TAHNSEADLEES(0.024)FNEHELEPS(0.053)S(0.924)PK ; 122.67 3.08E-07 106850000 5808.5 5238.3 4687.2 5430.2 6838.7 11819.9 4947.4 4645 7412 5614.9 TRUE FALSE FALSE 5348.751096 5691.075311 4860.911755 5407.731271 6757.152969 9368.319502 5086.210729 6061.239117 6598.922144 5810.017357 0.920608454 0.979528108 0.836643242 0.930759917 1.163017691 1.612442602 0.875420918 1.043239416 1.135783551 1 12.50432676 -5.738479836 7.520607425 0.950531013 1.184520645 0.221973831 0.187308933 0.178506194 40.90791538 0.025427249 0.050101325 1.83E-06 5.738479836 0.233989632 TAIT(ph)TPNFK ddPTM_HeLa_Curcumin_4h_R1 1 TAITTPNFK 9 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7;H0YMD2 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 0 TAIT(0.938)T(0.062)PNFK 157.78 0.0028947 73058000 4526.9 3675.5 3926.2 4442.8 4553.6 8937.8 8415.3 2119.3 5209.7 3577.6 TRUE FALSE FALSE 4168.591088 3993.193842 4071.708426 4424.416871 4499.301294 7083.99953 8651.410669 2765.464814 4638.208944 3701.921334 1.1260615 1.078681442 1.099890586 1.195167718 1.215396247 1.913600774 2.337005541 0.747035003 1.25291937 1 11.85405852 -5.398957483 4.417890197 1.0784381 1.729167923 0.282887652 0.377496241 0.166919426 5.239663311 0.048788614 0.112394173 3.99E-06 5.398957483 0.650729824 TAK(ac)VLVEDTK ddPTM_HeLa_Curcumin_4h_R1 1 TAKVLVEDTK 10 1 Q9Y490 Q9Y490 TLN1 Talin-1 0 1 TAK(1)VLVEDTK 107.34 0.0060516 2576800 3367.3 2748.3 2701.8 2748.5 2557.9 2252.1 1733.9 2185.7 3337.1 2962.2 FALSE TRUE FALSE 3100.774652 2985.850806 2801.931085 2737.127435 2527.398713 1784.989074 1782.548567 2852.109868 2971.028479 3065.13623 1.011627027 0.974133148 0.914129381 0.892987205 0.824563257 0.582352281 0.581556066 0.930500198 0.969297368 1 11.58173548 -5.881700953 1.363786551 1.000643353 0.690017718 0.595480903 0.096826959 0.180546885 0.67143548 0.014727113 0.034904765 1.31E-06 5.881700953 -0.310625635 TAKDS(ph)DDDDDVAVTVDRDR ddPTM_HeLa_Curcumin_4h_R1 2 TAKDSDDDDDVAVTVDRDR 19 2 A0A0C4DFZ1;A8MZ54;Q16623-3;Q16623-2;Q16623 A0A0C4DFZ1 STX1A Syntaxin-1A 1 0 T(0.109)AKDS(0.889)DDDDDVAVT(0.003)VDRDR;T(0.016)AKDS(0.646)DDDDDVAVT(0.338)VDRDR ; 112.64 0.00028605 52608000 2097.57 1658.03 1881.52 1720.36 1803.84 2169 1885.65 1861.73 2122.59 1930.32 TRUE FALSE FALSE 1931.545121 1801.342725 1951.250786 1713.241606 1782.330386 1719.12495 1938.556264 2429.362907 1889.747187 1997.398476 0.967030437 0.901844447 0.976896102 0.857736514 0.892325897 0.860682017 0.970540574 1.216263523 0.94610425 1 10.96390646 -4.265838632 5.337196898 0.954200107 1.226133497 0.714115522 0.052437701 0.075351019 7.6864689 0.008588576 0.074571517 5.42E-05 4.265838632 0.27193339 TAKDSDDDDDVAVT(ph)VDR ddPTM_HeLa_Curcumin_4h_R1 1 TAKDSDDDDDVAVTVDR 17 1 A0A0C4DFZ1;A8MZ54;Q16623-3;Q16623-2;Q16623 A0A0C4DFZ1 STX1A Syntaxin-1A 1 0 T(0.497)AKDSDDDDDVAVT(0.503)VDR 119.21 0.0065003 5417700 1052 960.67 1018.3 1018.3 770.8 1094.5 1032.2 773.11 1066.3 945.91 TRUE FALSE FALSE 968.7330899 1043.706034 1056.039094 1014.086544 761.6087134 867.4883624 1061.160754 1008.82768 949.3295578 978.7803021 0.989734967 1.066333305 1.078933742 1.036071672 0.778120189 0.886295281 1.084166438 1.030698797 0.969910771 1 9.934841257 TALIHDGLAR ddPTM_HeLa_Curcumin_4h_R1 3 TALIHDGLAR 10 0 P25398 P25398 RPS12 40S ribosomal protein S12 0 0 ;; ;; 125.68 0.0019995 83413700 15450.5 11656.7 13469.9 11905.3 12328 21184.1 15003.3 14363.9 14549.7 13844.2 FALSE FALSE TRUE 14227.57662 12664.25321 13969.10634 11856.03902 12180.99665 16790.27887 15424.25222 18743.38699 12953.63431 14325.28492 0.993179312 0.884048958 0.975136371 0.827630242 0.850314442 1.172072944 1.076715214 1.308412858 0.90424968 1 13.80627621 -4.510471924 1.344930399 0.968315557 1.338313623 0.627337468 0.087617755 0.478502401 1.033042125 0.013092961 0.211660431 3.09E-05 4.510471924 0.369998066 TALINSTGEEVAMR ddPTM_HeLa_Curcumin_4h_R1 3 TALINSTGEEVAMR 14 0 P02545;P02545-6;P02545-5;P02545-4;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ;; ;; 187.62 1.47E-08 11736900 2069.75 1580.53 2096.37 2097.21 2172.63 2104.62 2139.11 1954.63 1970.04 1956.49 FALSE FALSE TRUE 1905.927104 1717.14397 2174.063316 2088.532301 2146.722806 1668.098088 2199.127669 2550.587689 1753.931541 2024.477882 0.941441307 0.848191025 1.073888401 1.03163997 1.060383433 0.82396459 1.086269052 1.259874317 0.866362412 1 10.98333417 -4.428827288 3.803597222 0.972209975 1.251165329 0.541490148 0.085758352 0.129404236 3.14842505 0.010545659 0.072660348 3.73E-05 4.428827288 0.278955354 TALLDAAGVASLLTTAEVVVTEIPKEEK ddPTM_HeLa_Curcumin_4h_R1 1 TALLDAAGVASLLTTAEVVVTEIPKEEK 28 1 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 239.87 4.77E-46 3210400 1121.2 1152.2 810.67 1049.4 1360.6 1825.5 1238.5 1171.8 1168.7 1067.4 FALSE FALSE TRUE 1032.455837 1251.791034 840.7141433 1045.057861 1344.375734 1446.870722 1273.248977 1529.076426 1040.496534 1104.492071 0.934778858 1.133363532 0.761177165 0.94618865 1.217189122 1.309987424 1.152791415 1.384415938 0.942058854 1 10.10916735 -5.706101736 4.851424549 0.963212664 1.267091349 0.698478774 0.101037373 0.086102252 4.177941707 0.013889984 0.027935876 1.97E-06 5.706101736 0.303878685 TALPAQSAATLPAR ddPTM_HeLa_Curcumin_4h_R1 2 TALPAQSAATLPAR 14 0 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 ; ; 138.42 0.00037562 3850100 1954.33 1612.47 1628.01 1467.59 1712.04 2040.63 1264.27 1274.43 1853.7 2055.36 FALSE FALSE TRUE 1799.642718 1751.844722 1688.345483 1461.517501 1691.625041 1617.380335 1299.742014 1662.99784 1650.353748 2126.783607 0.846180454 0.823706143 0.793849208 0.687196148 0.795391236 0.760481852 0.611130352 0.78193091 0.775985738 1 11.05445754 -7.961649379 0.283256815 1.053259767 0.677964881 0.197771998 0.085944241 0.559216501 0.133815952 0.083054808 0.049761564 1.09E-08 7.961649379 -0.375294886 TALPTS(ph)GSSAAYWTR ddPTM_HeLa_Curcumin_4h_R1 1 TALPTSGSSAAYWTR 15 0 K7EMP4 K7EMP4 EPN1 1 0 T(0.001)ALPT(0.089)S(0.881)GS(0.029)SAAYWTR 62.813 0.019515 2412100 1522.2 1361.1 1381 1423.5 1625.8 1795.4 1185.6 1199.3 1612.7 1570 TRUE FALSE FALSE 1401.716264 1478.747419 1432.181075 1417.609934 1606.413397 1423.013802 1218.864745 1564.961049 1435.790845 1624.557383 0.862829641 0.910246344 0.881582325 0.872613026 0.988831428 0.875939389 0.750274972 0.963315341 0.883804327 1 10.66583099 -9.348272766 0.864937888 1.006693058 0.884689229 0 0.070101036 0.630967428 0.769149577 0.052835786 0.011159778 4.48E-10 9.348272766 -0.122003829 TALPTSGS(ph)SAGELELLAGEVPAR ddPTM_HeLa_Curcumin_4h_R1 1 TALPTSGSSAGELELLAGEVPAR 23 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 0 TALPT(0.002)S(0.127)GS(0.854)S(0.017)AGELELLAGEVPAR 138.04 1.51E-05 3867400 1644.8 1454 1425.6 1536.9 1547.1 2573.4 1531.8 3794.1 1791.4 1761.5 TRUE FALSE FALSE 1514.612344 1579.677281 1478.43399 1530.540715 1528.651843 2039.647832 1574.778185 4950.903624 1594.887902 1822.711994 0.830966356 0.86666313 0.811117716 0.839705187 0.838668889 1.119018166 0.863975324 2.716229246 0.875008179 1 10.8318709 -4.260603089 24.99852342 0.907500197 2.71622981 0.973157073 0.090771606 8.356106742 249738.8882 0.013762773 0.111300459 5.49E-05 4.260603089 1.808729613 TALPTSGSS(ph)AGELELLAGEVPAR ddPTM_HeLa_Curcumin_4h_R1 2 TALPTSGSSAGELELLAGEVPAR 23 0 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 0 TALPTSGS(0.041)S(0.959)AGELELLAGEVPAR;TALPTSGS(0.006)S(0.994)AGELELLAGEVPAR ; 350.49 1.55E-181 12742300 7162.8 6097.2 6359.9 5850.5 6157.7 7981.3 5186.9 9304.3 7333.4 6032 TRUE FALSE FALSE 6595.856822 6624.214799 6595.603489 5826.292181 6084.273449 6325.888412 5332.430454 12141.13824 6528.944367 6241.611551 1.056755418 1.061298792 1.05671483 0.933459593 0.974792071 1.01350242 0.854335521 1.945192862 1.046035037 1 12.60770286 -4.255490876 24.98328299 1.012394579 1.945193273 0.952291887 0.063433218 96.54942551 405488.842 0.008677885 0.105235689 5.55E-05 4.255490876 0.932798694 TALPTSGSSAGELELLAGEVPARS(ph)PGAFDMSGVR ddPTM_HeLa_Curcumin_4h_R1 1 TALPTSGSSAGELELLAGEVPARSPGAFDMSGVR 34 1 Q9Y6I3-3;Q9Y6I3;Q9Y6I3-1 Q9Y6I3-3 EPN1 Epsin-1 1 0 TALPTSGS(0.002)S(0.004)AGELELLAGEVPARS(0.938)PGAFDMS(0.055)GVR 56.22 0.0022853 23619000 2071.5 1647.5 1768.5 2090.5 1718.7 1850.6 1205.2 2524.2 2086.8 1842.8 TRUE FALSE FALSE 1907.538589 1789.902559 1834.042166 2081.850065 1698.205625 1466.764699 1239.014668 3293.81696 1857.883261 1906.837163 1.000367848 0.938676146 0.961824219 1.091781776 0.890587649 0.769213401 0.649774764 1.727371914 0.974327172 1 10.89696593 -5.737900978 24.96452522 0.99758272 0.966416624 0 0.271685613 2444.35409 2592434.869 0.036100183 0.072167249 1.83E-06 5.737900978 -0.031166096 TALQEEIK ddPTM_HeLa_Curcumin_4h_R1 1 TALQEEIK 8 0 P46940;H0YLE8;A0A0J9YXZ5;F2Z2E2;Q86VI3 P46940 IQGAP1;IQGAP3 Ras GTPase-activating-like protein IQGAP1;Ras GTPase-activating-like protein IQGAP3 0 0 106.42 0.0084887 2272200 1140.7 1028.4 950.73 1026.1 924.01 1466.9 985.24 1167.8 1609 1000.2 FALSE FALSE TRUE 1050.412391 1117.290314 985.9648901 1021.85427 912.9917842 1162.648405 1012.883183 1523.856844 1432.496726 1034.956876 1.014933488 1.07955253 0.952662776 0.98733995 0.882154422 1.123378599 0.978671872 1.472386802 1.384112478 1 10.01535494 -4.259471681 24.97801388 1.005086188 1.472386963 0.452230516 0.134979696 44.96536537 570747.8828 0.007774692 0.067412549 5.50E-05 4.259471681 0.467300774 TALSSTESCTMKGEEKS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 TALSSTESCTMKGEEKSPK 19 2 Q96T23-3;Q96T23-2;Q96T23;H0YER1;H0YCN2 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 0 TALS(0.001)S(0.003)T(0.003)ES(0.013)CT(0.005)MKGEEKS(0.976)PK 57.985 0.018754 46047000 3031.7 2470.3 2507.2 3297.3 2832.7 2979 2371.1 1714.6 3454.4 2673.4 TRUE FALSE FALSE 2791.737746 2683.821725 2600.119038 3283.656646 2798.921903 2361.12182 2437.626685 2237.373647 3075.460962 2766.300451 1.00919542 0.970184466 0.939926477 1.187020971 1.011792447 0.853530505 0.881186526 0.808796328 1.111759556 1 11.43374214 -5.259633975 9.15407771 1.011358038 0.851031577 0.575717168 0.07111044 0.058217613 87.13428262 0.00884881 0.021225795 5.50E-06 5.259633975 -0.160326461 TAMPS(ph)PGVSQNK ddPTM_HeLa_Curcumin_4h_R1 2 TAMPSPGVSQNK 12 0 Q86UU0-3;Q86UU0-4;Q86UU0-2;Q86UU0;A0A087WZX0 Q86UU0-3 BCL9L B-cell CLL/lymphoma 9-like protein 1 0 T(0.02)AMPS(0.977)PGVS(0.004)QNK;T(0.01)AMPS(0.973)PGVS(0.017)QNK ; 109 0.006854 17134400 7911.4 6705.3 7825.1 7401.5 7734 6860.2 6470.4 9862.8 6512.2 5443.9 TRUE FALSE FALSE 7285.204342 7284.876254 8115.10509 7370.874554 7641.777101 5437.31719 6651.94201 12869.92232 5797.827953 5633.07512 1.29329082 1.293232577 1.440617233 1.308499247 1.356590661 0.965248479 1.180872236 2.284706318 1.029247406 1 12.459707 -4.261214294 25 1.187976727 2.284706644 0.813173599 0.154642171 6.326676745 702255.4572 0.02435746 0.189361447 5.48E-05 4.261214294 1.096729916 MSS(ph)PEDDSDTKR ddPTM_HeLa_Curcumin_4h_R1 4 MSSPEDDSDTKR 12 1 Q15424-2;Q15424;Q15424-4;Q15424-3 Q15424-2 SAFB Scaffold attachment factor B1 1 0 MS(0.022)S(0.978)PEDDSDTKR;MS(0.023)S(0.977)PEDDSDTKR;MS(0.11)S(0.89)PEDDSDTKR;MS(0.194)S(0.806)PEDDSDTKR ;;; 110.51 0.002544 138742000 10820.7 10215.3 10035.2 10438.8 11150.4 16726.5 12663 19646.5 11948.2 10374.4 TRUE FALSE FALSE 9964.230177 11098.26501 10407.11334 10395.60701 11017.43876 13257.23535 13018.2897 25636.62741 10637.51235 10734.90963 0.92820811 1.033848015 0.969464458 0.968392597 1.026318725 1.234964784 1.212706036 2.388154935 0.990927052 1 13.39002243 -1.895796456 1.019944263 0.974887898 200 0.968731939 0.073530105 24.97094036 0.235075308 0.010627409 11376.04017 0.012711697 1.895796456 199.0251121 up TANSPGS(ph)GARPDPVR ddPTM_HeLa_Curcumin_4h_R1 1 TANSPGSGARPDPVR 15 1 A0A3B3ISR7;E9PIF2;Q13206 A0A3B3ISR7 DDX10 Probable ATP-dependent RNA helicase DDX10 1 0 T(0.001)ANS(0.328)PGS(0.671)GARPDPVR 130.02 0.0068998 15887000 2851 2586.5 2487.8 2849.6 2574 2925.7 1975.5 1282.8 2653.3 2157 TRUE FALSE FALSE 2625.340342 2810.065535 2580.000056 2837.80911 2543.306731 2318.876841 2030.927213 1673.919815 2362.239628 2231.955589 1.176251156 1.259014986 1.155937004 1.27144515 1.139497015 1.038943988 0.909931731 0.749978997 1.058372147 1 11.12409261 -4.596188553 1.761384892 1.121320179 0.733051762 0.716254759 0.081395759 0.276779375 1.326879511 0.015154063 0.143992743 2.53E-05 4.596188553 -0.388268417 ERDSASFNPELLT(ph)HILDGSPEK ddPTM_HeLa_Curcumin_4h_R1 1 ERDSASFNPELLTHILDGSPEK 22 1 I3L2U4;K7ELT1;I3L0T4;Q15067-2;Q15067 I3L2U4 ACOX1 Peroxisomal acyl-coenzyme A oxidase 1 1 0 ERDSASFNPELLT(0.972)HILDGS(0.028)PEK 49.655 0.010786 1131500 977.85 802.97 818.74 871.13 881.56 882.24 643.75 290.77 868.59 837.13 TRUE FALSE FALSE 900.4521407 872.3751488 849.0832246 867.5254949 871.0479728 699.2534791 661.8118924 379.4244345 773.3078501 866.2202052 1.039518745 1.007105518 0.980216369 1.00150688 1.005573372 0.807246789 0.764022691 0.438023071 0.892738181 1 9.758590014 -4.096437882 0.851550848 1.01730899 1.36E-20 0.913255645 0.051770851 0.337110519 0.14868602 0.005146497 0.342095564 8.01E-05 4.096437882 -1.01730899 down LTLNS(ph)PIFDKPLSR ddPTM_HeLa_Curcumin_4h_R1 1 LTLNSPIFDKPLSR 14 1 H0YBX5;E5RJM2;E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2;E5RIY8;E5RIU4 H0YBX5 CDK16 Cyclin-dependent kinase 16 1 0 LT(0.015)LNS(0.984)PIFDKPLS(0.001)R 127.66 0.011163 53614000 4741 3747.1 4497.3 4430 4308.1 4962.8 3544.4 1368.5 4387.7 4159.3 TRUE FALSE FALSE 4365.744847 4070.982627 4663.973894 4411.669834 4256.728721 3933.459338 3643.846325 1785.74935 3906.380287 4303.835365 1.014384724 0.945896458 1.08367851 1.025055435 0.989054729 0.913942798 0.846650956 0.41492046 0.907650957 1 12.07140718 -4.096267406 1.370137417 1.007403535 3.69E-14 0.924568059 0.049046473 0.241971123 0.298045938 0.005208597 0.373189603 8.01E-05 4.096267406 -1.007403535 down VDSLVSLS(ph)EEDLESDQREHR ddPTM_HeLa_Curcumin_4h_R1 2 VDSLVSLSEEDLESDQREHR 20 1 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2;A0A087WY36;H0YLH1;H0YMW2 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 VDSLVS(0.012)LS(0.988)EEDLESDQREHR;VDS(0.001)LVS(0.148)LS(0.851)EEDLESDQREHR ; 127.3 2.62E-05 11889500 5391 4364.2 4539.8 4948.4 4619.6 5407.4 3145.69 1791.29 6159.2 5218.8 TRUE FALSE FALSE 4964.296661 4741.422002 4708.048982 4927.924832 4564.514287 4285.844286 3233.949595 2337.446075 5483.55117 5400.152912 0.919288165 0.878016249 0.871836235 0.912552832 0.845256488 0.793652394 0.598862597 0.432848127 1.015443685 1 12.39878454 -4.094620717 0.600289983 0.955533277 8.42E-20 0.945016621 0.040256197 0.674201274 0.144012513 0.008094601 0.464602337 8.04E-05 4.094620717 -0.955533277 down TAPAAPAEDAVAAAAAAPSEPSEPSRPS(ph)PQPK ddPTM_HeLa_Curcumin_4h_R1 1 TAPAAPAEDAVAAAAAAPSEPSEPSRPSPQPK 32 1 Q53GA4 Q53GA4 PHLDA2 Pleckstrin homology-like domain family A member 2 1 0 TAPAAPAEDAVAAAAAAPS(0.025)EPS(0.052)EPS(0.089)RPS(0.834)PQPK 107.51 2.79E-09 0 1555.4 1625 1595.2 1568.9 1936.4 2188.3 1608.9 696.84 1600.1 1571.9 TRUE FALSE FALSE 1432.288449 1765.457759 1654.319515 1562.408308 1913.309695 1734.421913 1654.041404 909.3033081 1424.573033 1626.523408 0.880582746 1.085417984 1.017089276 0.960581508 1.176318573 1.06633689 1.016918291 0.55904717 0.875839245 1 10.66757587 -4.258824279 24.59551343 0.98540369 0.559046978 0.692036096 0.088780449 94.69423182 890550.4233 0.013410877 0.122035381 5.51E-05 4.258824279 -0.426356713 TVSLPLS(ph)SPNIK ddPTM_HeLa_Curcumin_4h_R1 2 TVSLPLSSPNIK 12 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;A0A0A0MQZ8;H0Y7Y3 Q8IWZ3-6 ANKHD1 Ankyrin repeat and KH domain-containing protein 1 1 0 TVSLPLS(0.814)S(0.186)PNIK;TVSLPLS(0.994)S(0.006)PNIK ; 157.68 0.00028261 278240000 11896.1 9458.5 11554.4 9956.6 9941.2 11976.9 9007.9 3145.3 10541.6 9087.2 TRUE FALSE FALSE 10954.51113 10276.05059 11982.61623 9915.402227 9822.657683 9492.755933 9260.63743 4104.287491 9385.212854 9402.979524 1.165004253 1.09285047 1.274342478 1.05449578 1.044632466 1.009547655 0.984862022 0.436487975 0.998110528 1 13.19890226 -4.093769587 1.763513329 1.088998017 2.82E-12 0.849219291 0.080855017 0.441221382 0.950721572 0.012619454 0.917273624 8.06E-05 4.093769587 -1.088998017 down TAPAAPTMAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 TAPAAPTMASPR 12 0 Q9H7P9-3;Q9H7P9;Q9H7P9-2 Q9H7P9-3 PLEKHG2 Pleckstrin homology domain-containing family G member 2 1 0 TAPAAPT(0.02)MAS(0.98)PR 115.24 0.0040522 4006700 1491 1089 1442.8 1161 1341.6 1709.4 958.02 1022.8 1546 1305.7 TRUE FALSE FALSE 1372.985777 1183.128308 1496.271437 1156.19609 1325.602296 1354.851171 984.8994628 1334.647012 1376.407668 1351.072978 1.016218812 0.875695338 1.107468998 0.85576139 0.981147812 1.002796439 0.728975769 0.987842281 1.018751533 1 10.39988989 -5.459247191 0.613186563 1.005032572 0.864774882 0.138156497 0.094807893 1.443267213 0.792248315 0.017338954 0.109794995 3.47E-06 5.459247191 -0.14025769 TAPPALPT(ph)GYDSEEEEESRPMSYDEK ddPTM_HeLa_Curcumin_4h_R1 2 TAPPALPTGYDSEEEEESRPMSYDEK 26 1 P25440-2;P25440;A0A0G2JK44;A0A140T9E9;H0Y6K2;P25440-3;P25440-4;A0A0G2JHN8;A0A140T9I1 P25440-2 BRD2 Bromodomain-containing protein 2 1 0 TAPPALPT(0.706)GY(0.147)DS(0.147)EEEEESRPMSYDEK;TAPPALPT(0.433)GY(0.433)DS(0.115)EEEEES(0.009)RPMS(0.005)Y(0.005)DEK ; 72.864 0.00024205 132987000 2554.6 2061.8 2814 2180.4 2681.1 2899.2 2169.4 2389.5 2073.52 2072.3 TRUE FALSE FALSE 2352.400714 2240.012805 2918.289315 2171.378083 2649.129634 2297.873239 2230.267525 3118.04755 1846.060044 2144.312271 1.097042043 1.044629943 1.360944185 1.012622141 1.235421571 1.071613156 1.040085232 1.454101435 0.860910078 1 11.0662993 -1.000001975 0.053049096 0.704785539 1.96263322 0.329051001 0.139716528 414.3340879 1.671483135 9.061455678 42.06137598 0.099999545 1.000001975 1.257847681 TAPPALPT(ph)GYDSEEEEESRPMSYDEKR ddPTM_HeLa_Curcumin_4h_R1 1 TAPPALPTGYDSEEEEESRPMSYDEKR 27 2 P25440-2;P25440;A0A0G2JK44;A0A140T9E9;H0Y6K2;P25440-3;P25440-4;A0A0G2JHN8;A0A140T9I1 P25440-2 BRD2 Bromodomain-containing protein 2 1 0 TAPPALPT(0.434)GY(0.377)DS(0.134)EEEEES(0.043)RPMS(0.008)Y(0.003)DEKR 50.77 0.0077065 21386000 2025 1762.6 1807.9 1933.6 1823.3 2439.6 1632 2188.7 2817.3 2005.8 TRUE FALSE FALSE 1864.719113 1914.95129 1874.902364 1925.599276 1801.558338 1933.59946 1677.789528 2856.024554 2508.249239 2075.501401 0.898442715 0.922645145 0.90334912 0.927775464 0.868011141 0.931630043 0.808377931 1.376064865 1.208502792 1 11.01924419 -4.251681018 24.94798413 0.930179105 1.376065111 0.622165863 0.101405682 379.7766198 970907.4231 0.008112615 0.144119171 5.60E-05 4.251681018 0.445886006 TAPPALPTGYDS(ph)EEEEESRPMSYDEKR ddPTM_HeLa_Curcumin_4h_R1 1 TAPPALPTGYDSEEEEESRPMSYDEKR 27 2 P25440-2;P25440;A0A0G2JK44;A0A140T9E9;H0Y6K2;P25440-3;P25440-4;A0A0G2JHN8;A0A140T9I1 P25440-2 BRD2 Bromodomain-containing protein 2 1 0 TAPPALPT(0.094)GY(0.064)DS(0.842)EEEEESRPMSYDEKR 114.19 1.13E-08 16072000 792.79 901.32 817.15 1015.6 1054.9 1423.5 857 953.21 1231.6 909.99 TRUE FALSE FALSE 730.039835 979.2260846 847.4342978 1011.397716 1042.321006 1128.250054 881.0451135 1243.839341 1096.496561 941.6120848 0.775308481 1.039946386 0.899982394 1.074112931 1.106953727 1.198211102 0.935677364 1.320967903 1.164488624 1 9.878989026 -6.183725857 1.503502322 0.900112042 1.135647537 0.140859839 0.139321734 0.282069418 1.250004986 0.01970909 0.037930938 6.55E-07 6.183725857 0.235535495 TAPPAS(ph)PEAR ddPTM_HeLa_Curcumin_4h_R1 4 TAPPASPEAR 10 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 TAPPAS(1)PEAR;TAPPAS(1)PEAR;TAPPAS(1)PEAR;TAPPAS(1)PEAR ;;; 158.08 0.00062576 1334530000 10279 9899.7 9457.8 8802.8 8847 11448.1 9023.3 7853.6 10566 8668.7 TRUE FALSE FALSE 9465.406304 10755.38596 9808.314388 8766.376346 8741.505303 9073.635013 9276.469513 10248.12649 9406.936235 8969.93668 1.055236691 1.199048147 1.093465287 0.97730638 0.974533669 1.011560654 1.034173355 1.142497082 1.048718243 1 13.13088209 -8.897196463 1.16324211 1.004984401 1.056805332 0.025435978 0.068226483 0.894275592 2.398684742 0.028668582 0.013253168 1.27E-09 8.897196463 0.051820931 TAPPGSAVGK(ac)QPAPR ddPTM_HeLa_Curcumin_4h_R1 2 TAPPGSAVGKQPAPR 15 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 0 1 ; TAPPGSAVGK(1)QPAPR;TAPPGSAVGK(1)QPAPR 128.36 0.0014433 4717900 1186.77 925.59 1013.53 860.9 1033.15 1571.2 894.61 644.24 730.02 852.61 FALSE TRUE FALSE 1092.835902 1005.593875 1051.092313 857.3378239 1020.830361 1245.315409 919.7103489 840.6658103 649.9386324 882.238134 1.23870853 1.139821366 1.191392973 0.971775976 1.157091631 1.411541126 1.042474037 0.952878569 0.736692971 1 9.785024311 -9.566562109 1.358049941 1.000403832 1.153752819 0.24383096 0.153203738 0.643495081 2.136107216 0.089395699 0.021237862 2.71E-10 9.566562109 0.153348986 TAPTALGIT(ph)LSSSPTSTPELR ddPTM_HeLa_Curcumin_4h_R1 1 TAPTALGITLSSSPTSTPELR 21 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 0 TAPTALGIT(0.315)LS(0.033)S(0.315)S(0.315)PT(0.02)S(0.001)T(0.001)PELR 254.02 3.06E-47 26862000 2692.9 1958.3 2027.9 2219.1 1941.5 2314.8 1699.7 1143.9 2178.5 2017.4 TRUE FALSE FALSE 2479.754123 2127.566726 2103.055758 2209.917952 1918.348881 1834.684387 1747.389007 1492.669844 1939.524 2087.5045 1.187903606 1.019191444 1.007449688 1.058641048 0.918967543 0.87888883 0.837070774 0.715049881 0.929111291 1 11.02756359 -5.072319562 0.721973149 1.084533852 0.689766193 0.650899236 0.073113978 0.502574272 0.33509151 0.013590918 0.129230585 8.47E-06 5.072319562 -0.394767658 TAPTALGITLSS(ph)SPTSTPELR ddPTM_HeLa_Curcumin_4h_R1 1 TAPTALGITLSSSPTSTPELR 21 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 0 TAPTALGITLS(0.002)S(0.899)S(0.081)PT(0.015)S(0.001)T(0.001)PELR 305.63 5.84E-103 23117000 3177.9 2695.2 2458.3 2605.6 2717.6 3259.4 2234.4 1631 3216.3 2424.4 TRUE FALSE FALSE 2926.365862 2928.161078 2549.406761 2594.818718 2685.194395 2583.363699 2297.09125 2128.284392 2863.479937 2508.64772 1.16651128 1.167226891 1.016247415 1.034349581 1.070375236 1.029783368 0.91566912 0.848379139 1.141443621 1 11.29269418 -4.507707457 1.058146253 1.081267152 0.774433836 0.680175684 0.055948176 0.72151161 0.833076729 0.011074445 0.224019857 3.11E-05 4.507707457 -0.306833316 TAPTALGITLSSS(ph)PTSTPELR ddPTM_HeLa_Curcumin_4h_R1 2 TAPTALGITLSSSPTSTPELR 21 0 F5H1U9;O75970-5;O75970-3;O75970-2;O75970 F5H1U9 MPDZ Multiple PDZ domain protein 1 0 TAPTALGITLSS(0.328)S(0.662)PT(0.008)S(0.002)TPELR;TAPTALGITLSS(0.022)S(0.973)PT(0.005)STPELR ; 285.06 7.85E-74 375230000 3171.9 2382.96 2589.17 2668.93 2978.4 3227.6 1976.26 1599.95 3219.8 2553.2 TRUE FALSE FALSE 2920.840768 2588.932444 2685.126918 2657.886675 2942.884525 2558.159377 2031.708537 2087.76739 2866.595996 2641.92351 1.105573555 0.979942241 1.016353012 1.006042251 1.113917384 0.968294263 0.769026253 0.790245207 1.085041253 1 11.36737298 -4.863828572 3.740492181 1.043310172 0.777345355 0.847105596 0.044181691 0.065253072 1.715004939 0.007056119 0.02436002 1.37E-05 4.863828572 -0.265964818 TAPTLS(ph)PEHWK ddPTM_HeLa_Curcumin_4h_R1 4 TAPTLSPEHWK 11 0 Q96JM3 Q96JM3 CHAMP1 Chromosome alignment-maintaining phosphoprotein 1 1 0 TAPT(0.027)LS(0.973)PEHWK;T(0.003)APT(0.031)LS(0.966)PEHWK;TAPT(0.082)LS(0.918)PEHWK;T(0.002)APT(0.245)LS(0.754)PEHWK ;;; 124.07 0.0017339 307125000 12894.7 10520.9 10679.2 11017.7 11100.9 14251.9 10822.7 7199.17 13525.1 11826.6 TRUE FALSE FALSE 11874.07089 11430.27972 11074.98055 10972.11168 10968.52902 11295.89529 11126.35583 9394.163792 12041.43037 12237.57347 0.970296188 0.93403155 0.904998084 0.896592098 0.896299339 0.923050253 0.909196244 0.767649225 0.983972059 1 13.5790299 -1 0.159490171 1.021843172 0.26736402 0.722626819 0.032410554 23.29652967 0.235224535 0.058633117 4.145557737 0.1 1 -0.754479152 TAPTSTIAPGVVMAS(ph)SPALPTQPAEEAAR ddPTM_HeLa_Curcumin_4h_R1 3 TAPTSTIAPGVVMASSPALPTQPAEEAAR 29 0 H7C1R5;C9JBT4;C9J896;P16220;P16220-1 H7C1R5 CREB1 Cyclic AMP-responsive element-binding protein 1 1 0 TAPTSTIAPGVVMAS(0.558)S(0.43)PALPT(0.012)QPAEEAAR;TAPTSTIAPGVVMAS(0.545)S(0.404)PALPT(0.051)QPAEEAAR;TAPTSTIAPGVVMAS(0.522)S(0.448)PALPT(0.029)QPAEEAAR ;; 159.89 1.40E-13 36891000 8604.6 7176.1 7051.88 8162.5 7580.79 9109 7858.4 3021.95 8676.3 6782.7 TRUE FALSE FALSE 7923.53683 7796.370108 7313.228876 8128.725738 7490.39403 7219.69072 8078.885554 3943.328644 7724.531597 7018.39832 1.128966535 1.110847483 1.042008239 1.158202394 1.0672512 1.028680675 1.151101033 0.56185592 1.100611741 1 12.77692611 -4.256118856 24.99918635 1.07337768 0.561855705 0.901829561 0.051841732 146.9843842 690603.8993 0.008323212 0.095428347 5.54E-05 4.256118856 -0.511521975 TAPTSTIAPGVVMASS(ph)PALPTQPAEEAAR ddPTM_HeLa_Curcumin_4h_R1 1 TAPTSTIAPGVVMASSPALPTQPAEEAAR 29 0 H7C1R5;C9JBT4;C9J896;P16220;P16220-1 H7C1R5 CREB1 Cyclic AMP-responsive element-binding protein 1 1 0 TAPTSTIAPGVVMAS(0.447)S(0.524)PALPT(0.03)QPAEEAAR 106.39 1.95E-10 7392800 3347.7 2550.4 2400.9 2977.6 2920.5 3401.8 2819.2 1095.6 3050.3 2774.2 TRUE FALSE FALSE 3082.726013 2770.845212 2489.879466 2965.27948 2885.674945 2696.228334 2898.299165 1429.643396 2715.689721 2870.603244 1.073894841 0.965248408 0.867371509 1.032981303 1.00525036 0.93925496 1.009648119 0.498028907 0.946034506 1 11.48713823 -4.26142158 11.58135519 1.010007311 0.497548547 0.849368356 0.060148946 0.017347482 168.9650862 0.008897552 0.068626093 5.48E-05 4.26142158 -0.512458764 TAPVQAPPAPVIVT(ph)ETPEPAMTSGVYRPPGAR ddPTM_HeLa_Curcumin_4h_R1 1 TAPVQAPPAPVIVTETPEPAMTSGVYRPPGAR 32 1 Q9UKY7-2;Q9UKY7;D6RFH2;D6R9V8;H0Y8K3;Q9UKY7-3;D6RAV0 Q9UKY7-2 CDV3 Protein CDV3 homolog 1 0 TAPVQAPPAPVIVT(0.278)ET(0.278)PEPAMT(0.155)S(0.155)GVY(0.134)RPPGAR 56.631 0.0012007 20627000 167.7 220.5 239.02 228.23 387.11 549.1 414.41 0 211.44 173.33 TRUE FALSE FALSE 154.426368 239.5590375 247.8782915 227.2856447 382.4939661 435.2104704 426.0372293 0 188.245561 179.3532046 0.86101817 1.335683062 1.382067814 1.267251652 2.132629673 2.426555307 2.375409072 0 1.049580137 1 7.486659713 -6.564491556 1.236628996 0.939331501 1.780196229 0.151185608 0.657591492 0.460647688 1.41067886 0.112196809 0.187011505 2.73E-07 6.564491556 0.840864727 TAQALSS(ph)GSGSQETK ddPTM_HeLa_Curcumin_4h_R1 1 TAQALSSGSGSQETK 15 0 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 0 TAQALS(0.195)S(0.399)GS(0.399)GS(0.007)QETK 168.05 1.30E-10 0 1271 686.8 963.51 781.45 983.57 826.59 498.34 531.89 590.97 570.08 TRUE FALSE FALSE 1170.399009 746.1639317 999.2185282 778.216567 971.8415701 655.1459164 512.3220792 694.0608125 526.1420695 589.8902376 1.984096251 1.264919953 1.693905857 1.319256562 1.647495599 1.110623426 0.868504082 1.17659315 0.891932153 1 9.204302723 -5.1270036 5.34999352 1.475753317 1.01566739 0.176270017 0.319484373 0.25892031 10.17491798 0.052543218 0.138078474 7.46E-06 5.1270036 -0.460085928 AAHTEDINACT(ph)LTTSPR ddPTM_HeLa_Curcumin_4h_R1 1 AAHTEDINACTLTTSPR 17 0 H7C155;P04049;P04049-2 H7C155 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 0 AAHTEDINACT(0.389)LT(0.204)T(0.204)S(0.204)PR 137.39 0.00033559 106120000 2114.2 1793.6 2203.8 1941 2353.6 3288.2 2661.6 4199.7 2777.3 2089.4 TRUE FALSE FALSE 1946.858839 1948.630792 2285.474767 1932.968656 2325.534857 2606.190254 2736.277333 5480.169197 2472.637138 2162.006494 0.900487045 0.901306632 1.057108187 0.894062373 1.075637313 1.205449781 1.265619386 2.534760747 1.143677017 1 11.07815514 -1.882350586 0.990280828 0.956947752 200 0.952823804 0.100417601 23.36668351 0.231652917 0.012303327 10310.29537 0.01311141 1.882350586 199.0430522 up TAQALSSGS(ph)GSQETK ddPTM_HeLa_Curcumin_4h_R1 1 TAQALSSGSGSQETK 15 0 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 0 TAQALS(0.008)S(0.012)GS(0.949)GS(0.03)QETK 219.85 1.76E-14 9551100 2374.1 1502.2 2223.8 2393.2 2290.4 2435 2004.3 1713.6 1703.2 1863 TRUE FALSE FALSE 2186.18748 1632.043474 2306.215984 2383.297573 2263.088476 1929.953552 2060.535264 2236.068752 1516.363221 1927.739111 1.134068125 0.846610138 1.196331999 1.236317486 1.173959932 1.001148724 1.068886994 1.159943655 0.786601886 1 10.9126941 -13.236043 0.283111471 0.313043089 1.114070981 0.24152954 0.124863999 67.62321182 1.060595678 26.1550445 0.050576471 5.81E-14 13.236043 0.801027892 TAQALSSGSGS(ph)QETK ddPTM_HeLa_Curcumin_4h_R1 1 TAQALSSGSGSQETK 15 0 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 0 TAQALSSGS(0.001)GS(0.991)QET(0.009)K 234.36 2.92E-21 9160800 2302.7 1797.7 1904.4 1940.7 2416.1 2482.8 2324.4 2249 1773.3 1784.1 TRUE FALSE FALSE 2120.438865 1953.085178 1974.978739 1932.669898 2387.289586 1967.839293 2389.616408 2934.709747 1578.773427 1846.097342 1.148606207 1.057953518 1.069812893 1.046894903 1.293154771 1.065945575 1.294415172 1.589683101 0.855195114 1 10.85026291 -1.00000002 0.670220169 1.071417789 54.29589598 0.724640458 0.101761275 74.39892972 0.413067132 0.013647322 5911.612227 0.099999995 1.00000002 53.22447819 TAQALSSGSGS(ph)QETKIPISLVLR ddPTM_HeLa_Curcumin_4h_R1 1 TAQALSSGSGSQETKIPISLVLR 23 1 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 0 TAQALS(0.015)S(0.166)GS(0.119)GS(0.697)QET(0.002)KIPISLVLR 92.545 6.83E-05 76262000 1771.4 1420.5 1406.4 1470.3 1407.2 2475.8 1711 1706.5 1788.6 1455.8 TRUE FALSE FALSE 1631.191821 1543.28169 1458.522421 1464.216288 1390.420059 1962.291172 1759.006055 2226.803994 1592.395055 1506.388942 1.082849041 1.024490852 0.968224328 0.97200414 0.923015312 1.302645763 1.167697137 1.478239738 1.057094228 1 10.5568786 -4.402010746 1.069829626 1.02427843 1.593892862 0.735606342 0.084734948 0.561029815 0.593606104 0.012775184 0.340362892 3.96E-05 4.402010746 0.569614432 TAQAS(ph)PNTELDFGGAAGSDVDQEEIVDER ddPTM_HeLa_Curcumin_4h_R1 1 TAQASPNTELDFGGAAGSDVDQEEIVDER 29 0 D6RA38;Q9UBS8-2;Q9UBS8 D6RA38 RNF14 E3 ubiquitin-protein ligase RNF14 1 0 T(0.31)AQAS(0.668)PNT(0.021)ELDFGGAAGSDVDQEEIVDER 158.13 1.56E-13 6052300 1650.1 1671 1492.4 1632.4 1664.3 1926.4 1502.1 1670.7 1571.8 1809.9 TRUE FALSE FALSE 1519.492844 1815.433794 1547.709657 1625.645561 1644.454309 1526.842925 1544.244883 2180.088739 1399.377472 1872.79389 0.811350812 0.969371912 0.826417506 0.868032286 0.878075435 0.815275473 0.82456745 1.164083645 0.747213818 1 10.87097642 -9.568803183 1.34327971 1.000070072 0.878382225 0 0.128474389 0.617538704 1.99541676 0.0679287 0.015898568 2.70E-10 9.568803183 -0.121687847 TAQASPNT(ph)ELDFGGAAGSDVDQEEIVDER ddPTM_HeLa_Curcumin_4h_R1 1 TAQASPNTELDFGGAAGSDVDQEEIVDER 29 0 D6RA38;Q9UBS8-2;Q9UBS8 D6RA38 RNF14 E3 ubiquitin-protein ligase RNF14 1 0 T(0.008)AQAS(0.018)PNT(0.974)ELDFGGAAGSDVDQEEIVDER 123.18 2.41E-12 6661300 1844.8 1517.2 1983 2033.2 1857 2634.2 1805 1793.5 2339.4 2005.9 TRUE FALSE FALSE 1698.782133 1648.340007 2056.491724 2024.787157 1834.856488 2087.837226 1855.643442 2340.329894 2082.773673 2075.604876 0.818451601 0.794149227 0.990791527 0.97551667 0.884010492 1.005893391 0.894025382 1.127541143 1.003453835 1 11.01931611 TAQDLSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 TAQDLSSPR 9 0 Q9UHI6;Q9UHI6-2 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 1 0 TAQDLS(0.028)S(0.972)PR 100.04 0.013108 50574000 5537.2 4331.3 5246.2 4834.9 5135.6 8342.2 6228 2408 5164.9 3564.6 TRUE FALSE FALSE 5098.924777 4705.678272 5440.628787 4814.894465 5074.361324 6611.933684 6402.740918 3142.188115 4598.323392 3688.469585 1.382395777 1.27578069 1.475036912 1.305390855 1.375736253 1.79259542 1.735880091 0.851894815 1.246675155 1 11.84880662 -9.312573222 0.379559968 0.847122577 1.458634927 0.122511376 0.256636973 2.532374456 0.464737456 0.641815606 0.091426002 4.87E-10 9.312573222 0.61151235 TAQDPGISPS(ph)QSLCAESSR ddPTM_HeLa_Curcumin_4h_R1 1 TAQDPGISPSQSLCAESSR 19 0 A0A0A0MT72;Q9BSQ5-4;Q9BSQ5;Q9BSQ5-2;A0A3B3IRS0;E9PEC4 A0A0A0MT72 CCM2 Cerebral cavernous malformations 2 protein 1 0 TAQDPGIS(0.356)PS(0.598)QS(0.046)LCAESSR 181.32 2.74E-07 11787000 776.37 827.25 822.8 741.56 659.14 1231.7 861.11 712.05 944.07 696.77 TRUE FALSE FALSE 714.9194953 898.7538038 853.2936918 738.4916212 651.280186 976.2315359 885.270429 929.1507671 840.5078829 720.9827056 0.991590353 1.24656777 1.183514785 1.024284793 0.903322897 1.354029061 1.227866386 1.288728231 1.165780921 1 9.493820843 -1 0.224845328 0.978202632 2.829174974 0.145600107 0.130908814 36.59433071 0.441456612 0.086277505 24.99571266 0.1 1 1.850972341 TAQEKDSLIT(ph)PHVS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 TAQEKDSLITPHVSR 15 1 P49792;J3KNE0;J3KQ37;A6NKT7;Q99666;O14715;F8VYC4;P0DJD0;P0DJD1;A0A1W2PNU4;A0A286YES2;Q7Z3J3;H7BZ48 P49792 RANBP2;RGPD3;RGPD8;RGPD5;RGPD1;RGPD2;RGPD4;RGPD6 E3 SUMO-protein ligase RanBP2;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4 2 0 T(0.002)AQEKDS(0.014)LIT(0.985)PHVS(1)R 104.78 0.011782 4016900 2565.5 2608 2483.3 2506.6 2399.9 2938.5 2388 1653.2 3311.2 2859 TRUE FALSE FALSE 2362.437968 2833.423899 2575.333283 2496.228353 2371.28276 2329.021976 2455.000853 2157.25307 2947.969644 2958.350037 0.798566072 0.957771685 0.870530279 0.843790735 0.801555844 0.787270589 0.829854758 0.729208188 0.996491155 1 11.53057705 -13.52287875 0.196339465 1.800109565 0.788204799 0.672624692 0.050737649 26.83756995 0.322816813 8.268427888 0.060090127 3.00E-14 13.52287875 -1.011904766 TAQEVETYRR ddPTM_HeLa_Curcumin_4h_R1 2 TAQEVETYRR 10 1 P17844-2;P17844;J3KTA4;J3QRQ7;J3QR02;J3KRX8;J3KTQ4 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 0 ; ; 130.56 0.0041617 16342100 5861.2 4715.8 5133.8 4952.3 5106.3 6676.5 5239.3 5565.2 6650.7 5800.5 FALSE FALSE TRUE 5397.279835 5123.412739 5324.063144 4931.808695 5045.410708 5291.71864 5386.300657 7262.003861 5921.134849 6002.066943 0.899236861 0.853608063 0.887038281 0.821685053 0.840612202 0.881649387 0.897407628 1.209917172 0.986515963 1 12.55124369 -4.259089725 24.69182351 0.916947636 1.209917294 0.716563658 0.057868325 97.08868684 1020196.902 0.010026019 0.090047654 5.51E-05 4.259089725 0.292969658 TAQSPAMVGS(ph)PIR ddPTM_HeLa_Curcumin_4h_R1 1 TAQSPAMVGSPIR 13 0 Q5VWG9 Q5VWG9 TAF3 Transcription initiation factor TFIID subunit 3 1 0 TAQSPAMVGS(1)PIR 85.734 0.016568 7960900 1255.5 1019.2 873.67 827.24 1159.1 1164.7 778.84 813.75 987.33 887.87 TRUE FALSE FALSE 1156.12585 1107.295107 906.0489788 823.8171001 1145.27849 923.1280911 800.6921543 1061.858629 879.0223692 918.7234164 1.258404684 1.205254037 0.986204295 0.896697619 1.246597691 1.004794342 0.871526882 1.155797937 0.956786725 1 9.84348679 -6.74915653 24.94879608 1.131676164 1.02293058 0.062040007 0.133272304 367.9374157 747348.4165 0.022168849 0.03121937 1.78E-07 6.74915653 -0.108745584 TAQVPS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 2 TAQVPSPPR 9 0 S4R3H4;E7EQT4;Q9UKV3;G3V3B0;Q9UKV3-3;Q9UKV3-2;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 TAQVPS(1)PPR;TAQVPS(1)PPR ; 112.64 0.0082961 1511520000 3803 3169.1 3397.9 3569.6 3914.4 4485.9 3533.6 3045.2 3625.2 3345.5 TRUE FALSE FALSE 3501.988537 3443.022883 3523.829163 3554.829941 3867.723337 3555.473773 3632.743306 3973.667462 3227.52463 3461.755876 1.011622039 0.994588586 1.017931157 1.026886375 1.117272123 1.027072359 1.049393266 1.147876281 0.932337445 1 11.75728827 -5.939448829 5.936727039 1.006138031 1.078568642 0.54109711 0.039511029 0.112006191 7.851582491 0.004455191 0.008126524 1.15E-06 5.939448829 0.072430611 TAS(ph)EINFDK ddPTM_HeLa_Curcumin_4h_R1 1 TASEINFDK 9 0 Q9Y4K4 Q9Y4K4 MAP4K5 Mitogen-activated protein kinase kinase kinase kinase 5 1 0 T(0.003)AS(0.997)EINFDK 101.71 0.012127 5050100 1705.8 1573.7 1968.7 1866.5 1980.7 1888.6 1854.4 994.08 1856.2 1786.3 TRUE FALSE FALSE 1570.78413 1709.723616 2041.661754 1858.776918 1957.081446 1496.883071 1906.429473 1297.170416 1652.579504 1848.373792 0.849819521 0.924988021 1.104571901 1.005628259 1.058812592 0.809837857 1.031409059 0.701790093 0.894072136 1 10.85204082 -4.249257007 24.23637467 0.95010555 0.701789858 0.425324968 0.090201175 1032.141639 2053350.19 0.01321956 0.288317127 5.63E-05 4.249257007 -0.248315693 TAS(ph)ELLLDR ddPTM_HeLa_Curcumin_4h_R1 2 TASELLLDR 9 0 Q92508 Q92508 PIEZO1 Piezo-type mechanosensitive ion channel component 1 1 0 T(0.03)AS(0.97)ELLLDR;T(0.022)AS(0.978)ELLLDR ; 143.24 2.85E-05 3791600 2894.8 2724.5 2798.8 4819.7 3064.2 5925.7 2334.6 962.86 5150.3 3887 TRUE FALSE FALSE 2665.673525 2959.99364 2902.52599 4799.757358 3027.661416 4696.643024 2400.102593 1256.431582 4585.324975 4022.072961 0.662761106 0.735937331 0.721649264 1.193354125 0.752761436 1.167717013 0.596732734 0.312384085 1.140040228 1 11.97372354 -4.531761428 8.348353118 0.858979948 0.381312803 0.472431138 0.198642639 0.075883054 43.51117337 0.026515244 0.10637803 2.94E-05 4.531761428 -0.477667145 TAS(ph)FSESR ddPTM_HeLa_Curcumin_4h_R1 5 TASFSESR 8 0 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 1 0 T(0.003)AS(0.997)FSESR;T(0.043)AS(0.957)FSESR;T(0.001)AS(0.999)FSESR;T(0.005)AS(0.99)FS(0.004)ESR;TAS(0.993)FS(0.007)ESR ;;;; 122.94 0.0073567 10044923000 14472.2 13085.2 14646 13794.8 15732.4 17691.5 17415.9 12612.9 13361.2 12569.2 TRUE FALSE FALSE 13326.7101 14216.22638 15188.79364 13737.72077 15544.80141 14022.08348 17904.54328 16458.51515 11895.50979 13005.97876 1.0246603 1.093053175 1.16783165 1.056261972 1.195204274 1.07812597 1.376639437 1.265457636 0.914618577 1 13.66688735 -1.762195559 0.231110638 0.983894753 2.42192946 0.680738419 0.073039988 12.67485711 0.210725285 0.042429276 6.484145611 0.017290376 1.762195559 1.438034707 TAS(ph)FSESRADEVAPAK ddPTM_HeLa_Curcumin_4h_R1 2 TASFSESRADEVAPAK 16 1 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 1 0 T(0.196)AS(0.785)FS(0.02)ESRADEVAPAK;T(0.378)AS(0.508)FS(0.065)ES(0.049)RADEVAPAK ; 149.86 0.0033495 393600000 9970.2 8893 8744.7 10686.1 9652.2 12944.3 11907.2 9660.8 13009.4 11063.2 TRUE FALSE FALSE 9181.048149 9661.671294 9068.786275 10641.88375 9537.103819 10259.50627 12241.28399 12606.33345 11582.30137 11447.64538 0.802003193 0.843987648 0.792196646 0.929613331 0.833106155 0.896211049 1.069327672 1.101216279 1.011762768 1 13.48276327 -4.742972333 4.622399388 0.887440201 1.09217444 0.54881394 0.071583389 0.12204809 6.306722197 0.01172405 0.043995221 1.81E-05 4.742972333 0.204734239 TAS(ph)FSESRADEVAPAKK ddPTM_HeLa_Curcumin_4h_R1 3 TASFSESRADEVAPAKK 17 2 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 1 0 T(0.093)AS(0.483)FS(0.115)ES(0.309)RADEVAPAKK;T(0.41)AS(0.587)FS(0.003)ESRADEVAPAKK;T(0.168)AS(0.581)FS(0.199)ES(0.052)RADEVAPAKK ;; 147.84 0.00018114 718786000 8565.3 6700.7 7018.6 7840.7 6286.5 10819.1 7602.4 6327.2 10898.8 8292.5 TRUE FALSE FALSE 7887.347467 7279.87865 7278.71549 7808.257261 6211.537593 8575.096704 7815.702883 8256.334153 9703.228907 8580.663758 0.919200156 0.848405072 0.848269516 0.909982897 0.723899429 0.999351209 0.910850618 0.962202271 1.130824978 1 13.06687354 -8.365882603 0.89493265 0.989823186 0.88629138 0.346342211 0.08384769 0.502041911 0.84087537 0.024963906 0.014937226 4.31E-09 8.365882603 -0.103531807 SGCSEAQPPES(ph)PETR ddPTM_HeLa_Curcumin_4h_R1 2 SGCSEAQPPESPETR 15 0 A0A494BZT8;Q9Y6A5;H0Y8F2;A0A494C117 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 0 SGCSEAQPPES(0.989)PET(0.011)R;SGCSEAQPPES(0.671)PET(0.329)R ; 137.91 0.00057504 107722000 3532.9 2925.8 2919.5 3141.6 3263.1 4896 3392.4 4852 3833.6 2908.4 TRUE FALSE FALSE 3253.267237 3178.693115 3027.699238 3128.600892 3224.189664 3880.514411 3487.581614 6331.352464 3413.063671 3009.466684 1.081011215 1.056231369 1.006058401 1.039586485 1.07134918 1.28943591 1.158870318 2.103812114 1.13410914 1 11.55529213 -1.878000976 1.071985616 1.043166666 199.9999998 0.930445235 0.082783342 46.15126691 0.358553369 0.011057537 22216.00629 0.013243386 1.878000976 198.9568332 up TAS(ph)LPGYGR ddPTM_HeLa_Curcumin_4h_R1 1 TASLPGYGR 9 0 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 T(0.002)AS(0.998)LPGYGR 109.83 0.00553 11780000 10178 8577.6 7780.2 8095.2 7940.5 9407.1 7892.3 5417.7 10552 9931 TRUE FALSE FALSE 9372.40056 9319.009523 8068.541056 8061.704207 7845.814724 7455.96142 8113.736697 7069.53179 9394.472 10276.10151 0.912057997 0.906862346 0.785175297 0.784509982 0.763501092 0.725563232 0.789573428 0.68795854 0.914205839 1 13.32700543 -6.89136349 0.496123334 0.989397306 0.717190683 0.843917431 0.037429102 0.165853368 0.091898946 0.010463701 0.017052263 1.28E-07 6.89136349 -0.272206623 TAS(ph)NPKVENEDEPVR ddPTM_HeLa_Curcumin_4h_R1 2 TASNPKVENEDEPVR 15 1 Q9UBF8-2 Q9UBF8-2 PI4KB Phosphatidylinositol 4-kinase beta 1 0 T(0.083)AS(0.917)NPKVENEDEPVR;T(0.228)AS(0.772)NPKVENEDEPVR ; 71.529 0.011926 533430000 11820.9 10263.1 10061.2 11823.1 11764.5 11998.4 9572.1 9579.3 12154.5 12244.6 TRUE FALSE FALSE 10885.26329 11150.19663 10434.07692 11774.17914 11624.21602 9509.79659 9840.667364 12499.98447 10821.18176 12670.09894 0.859130094 0.880040218 0.823519767 0.929288651 0.917452664 0.750570034 0.776684335 0.986573549 0.854072396 1 13.62914017 -9.318232815 0.553850336 1.028388858 0.857366997 0 0.081042347 1.165415941 0.485545771 0.105865398 0.016103136 4.81E-10 9.318232815 -0.171021861 TAS(ph)PPPPPK ddPTM_HeLa_Curcumin_4h_R1 5 TASPPPPPK 9 0 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 T(0.15)AS(0.85)PPPPPK;TAS(1)PPPPPK;T(0.013)AS(0.987)PPPPPK;T(0.19)AS(0.81)PPPPPK;T(0.196)AS(0.804)PPPPPK ;;;; 120.45 0.0061181 1635080800 38191.9 39433.9 37795.6 39576.1 35486.8 44918.6 39079.8 48022.3 45858.8 41066.8 TRUE FALSE FALSE 35168.97082 42842.3906 39196.33818 39412.34458 35063.64309 35601.97602 40176.27401 62664.0782 40828.20437 42493.86824 0.827624603 1.008201709 0.922399862 0.927483098 0.825145945 0.837814431 0.945460502 1.474661658 0.960802254 1 15.37496706 -4.263349147 4.981296034 0.912597473 1.50195602 0.875425997 0.063181271 0.048797248 3.725746131 0.010529383 0.098647281 5.45E-05 4.263349147 0.589358546 TAS(ph)PPPPPKR ddPTM_HeLa_Curcumin_4h_R1 2 TASPPPPPKR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 T(0.053)AS(0.947)PPPPPKR;T(0.169)AS(0.831)PPPPPKR ; 112.64 0.0030315 678650000 11246.5 10064.4 10521.3 11154.2 11357.7 14599.8 11744.8 17115.2 13300.2 11918.8 TRUE FALSE FALSE 10356.32766 10934.32189 10911.22863 11108.04688 11222.26685 11571.63691 12074.32748 22333.54569 11841.20134 12332.97741 0.839726476 0.886592225 0.884719745 0.900678442 0.909939787 0.938267907 0.979027778 1.810880288 0.960125113 1 13.59023352 -4.257872462 4.146019403 0.916235347 1.887531486 0.976120276 0.041808255 0.033810606 1.268407737 0.008416282 0.097810519 5.52E-05 4.257872462 0.971296138 TAS(ph)PSTSSIDSATDTR ddPTM_HeLa_Curcumin_4h_R1 2 TASPSTSSIDSATDTR 16 0 Q96P50-4;Q96P50-1;Q96P50 Q96P50-4 ACAP3 "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3" 1 0 TAS(0.998)PS(0.002)TSSIDSATDTR;TAS(0.991)PS(0.006)T(0.002)SSIDSATDTR ; 219.95 2.04E-15 18489000 5402.9 4832 4512.2 4981.2 4508.9 5860 4548.3 2720.62 5574 5123.8 TRUE FALSE FALSE 4975.254764 5249.656549 4679.426101 4960.589114 4455.134312 4644.569944 4675.913057 3550.124514 4962.546145 5301.851669 0.938399464 0.990155304 0.882602229 0.935633327 0.840297804 0.876027893 0.881939622 0.669600875 0.936002449 1 12.37228059 -2.372076749 0.30425175 0.983155204 5.90E-17 0.722597135 0.047042803 7.704548639 0.207982405 0.016482494 3.563104059 0.004245445 2.372076749 -0.983155204 TAS(ph)TNNIAQAR ddPTM_HeLa_Curcumin_4h_R1 1 TASTNNIAQAR 11 0 Q9UBI6 Q9UBI6 GNG12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 1 0 T(0.037)AS(0.907)T(0.055)NNIAQAR 113.52 0.0054149 7681000 1101.7 668.83 915.73 1011.8 753.62 1251.8 2539.2 1767.6 1404.9 988.58 TRUE FALSE FALSE 1014.499282 726.640685 949.6677594 1007.61344 744.6335737 992.1625693 2610.443118 2306.533103 1250.785985 1022.933081 0.991755278 0.710350167 0.928377209 0.985023808 0.727939674 0.96991933 2.551919735 2.254823062 1.222744682 1 9.998496054 -4.765498422 24.99171629 0.949430572 2.403371665 0.936532183 0.152161207 12.26514804 75519.44701 0.017645697 0.055912291 1.72E-05 4.765498422 1.453941093 TASAPNLAETEKET(ph)AEHLDLAGASSRPK ddPTM_HeLa_Curcumin_4h_R1 1 TASAPNLAETEKETAEHLDLAGASSRPK 28 2 Q86W92-3;Q86W92-4;Q86W92;F5GZP6 Q86W92-3 PPFIBP1 Liprin-beta-1 1 0 T(0.108)AS(0.333)APNLAET(0.114)EKET(0.445)AEHLDLAGASSRPK 57.735 0.00099673 5086900 2494.4 2082.5 2124.8 2182.5 2223.1 3529.1 1991.5 1673.7 3279.1 1870 TRUE FALSE FALSE 2296.965608 2262.502021 2203.546957 2173.469393 2196.590984 2797.124879 2047.37613 2184.003425 2919.390934 1934.982361 1.187073151 1.169262349 1.138794338 1.123250236 1.135199488 1.445555751 1.058085165 1.12869423 1.508742918 1 10.9181047 -9.359540436 0.609205781 0.968244664 1.178552647 0 0.187376694 1.18499048 0.603782307 0.141418624 0.021608654 4.37E-10 9.359540436 0.210307983 TASDTDSSYCIPT(ph)AGMSPSR ddPTM_HeLa_Curcumin_4h_R1 1 TASDTDSSYCIPTAGMSPSR 20 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 0 TASDTDSSYCIPT(0.554)AGMS(0.411)PS(0.035)R 128.1 0.0019324 5020200 2095 1481.7 1884 1669.2 1470.3 2068.6 1191.8 807.13 2144.9 1705.9 TRUE FALSE FALSE 1929.178539 1609.771546 1953.822697 1662.293293 1452.767633 1639.549042 1225.2387 1053.220221 1909.609836 1765.179898 1.092907608 0.911958916 1.10686888 0.941713247 0.823013923 0.928828299 0.694115485 0.596664523 1.081821654 1 10.78559951 -4.14175161 0.544651194 1.041762541 0.215513737 0.810086502 0.070665898 1.25651142 0.229022056 0.013693065 0.675403709 7.22E-05 4.14175161 -0.826248804 TASDTDSSYCIPTAGMS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 3 TASDTDSSYCIPTAGMSPSR 20 0 Q13480-2;B7Z3B9;Q13480 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 0 TASDTDS(0.002)S(0.009)Y(0.006)CIPT(0.062)AGMS(0.809)PS(0.111)R;T(0.002)AS(0.008)DT(0.001)DSSYCIPTAGMS(0.823)PS(0.166)R;TASDTDSSYCIPTAGMS(0.994)PS(0.006)R ;; 282.41 2.43E-69 24114700 7039.8 7026.5 5690.7 6927.1 6736.7 6079.96 3901.96 2505.67 6757.2 6503.9 TRUE FALSE FALSE 6482.592402 7633.839351 5901.602348 6898.437496 6656.369252 4818.907761 4011.438496 3269.637248 6015.952066 6729.910041 0.963250974 1.134315214 0.876921432 1.025041561 0.989072545 0.716043414 0.596061236 0.485836694 0.893912702 1 12.71637151 -5.00786114 1.884944433 0.991159619 0.514345776 0.867491958 0.071014252 0.074239694 0.498800944 0.0087145 0.036906255 9.82E-06 5.00786114 -0.476813843 TASEGDGGAAAGAAAAGARPVS(ph)VAGSPLS(ph)PGPVR ddPTM_HeLa_Curcumin_4h_R1 1 TASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVR 34 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 2 0 T(0.003)AS(0.006)EGDGGAAAGAAAAGARPVS(0.599)VAGS(0.498)PLS(0.895)PGPVR 48.163 0.0095489 10037000 1639 1384.7 1364.5 1515.5 1370.1 2300.5 1932.6 902.05 1618.1 1612.3 TRUE FALSE FALSE 1509.271421 1504.387298 1415.06957 1509.229263 1353.762452 1823.350368 1986.823555 1177.080892 1440.598478 1668.327305 0.904661463 0.901733906 0.848196614 0.904636193 0.811448957 1.092921253 1.190907533 0.705545542 0.863498712 1 10.70418664 -4.175295109 21.63290366 0.951539584 0.705508846 0.294485743 0.111610325 75849.83931 19038318.95 0.015213811 455.050045 6.68E-05 4.175295109 -0.246030738 TASEGDGGAAAGAAAAGARPVSVAGSPLS(ph)PGPVR ddPTM_HeLa_Curcumin_4h_R1 2 TASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVR 34 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 TASEGDGGAAAGAAAAGARPVS(0.133)VAGS(0.101)PLS(0.766)PGPVR;TASEGDGGAAAGAAAAGARPVS(0.047)VAGS(0.034)PLS(0.92)PGPVR ; 79.497 6.33E-08 29966000 1659.22 1322.11 1227.63 1552.25 1418.05 1755.65 1406.23 962.47 1774.15 1425.04 TRUE FALSE FALSE 1527.890986 1436.387297 1273.127048 1545.827201 1401.14068 1391.5084 1445.685029 1255.922672 1579.530184 1474.560034 1.036167366 0.974112457 0.863394517 1.04833114 0.950209315 0.943677007 0.980417885 0.851727053 1.071187437 1 10.52606884 -1 0.276113511 1.016174765 0.072140669 0.35978263 0.055538341 40.25942734 0.512206406 0.023439596 18.49265654 0.1 1 -0.944034096 TASES(ph)ISNLS(ph)EAGSIKKGER ddPTM_HeLa_Curcumin_4h_R1 1 TASESISNLSEAGSIKKGER 20 2 F5H1T5;F5H6A0;J3KP58;P30622-2;P30622-1;P30622 F5H1T5 CLIP1 CAP-Gly domain-containing linker protein 1 2 0 T(0.004)AS(0.056)ES(0.801)IS(0.161)NLS(0.943)EAGS(0.035)IKKGER 65.881 0.0062768 18149000 2369.8 2585.7 2404.4 3154.5 2772.6 4054.9 3353.3 3457.5 3993.5 3909.1 TRUE FALSE FALSE 2182.227829 2809.196386 2493.509179 3141.447515 2739.538556 3213.868032 3447.384573 4511.675834 3555.423041 4044.940934 0.539495598 0.694496269 0.61645132 0.77663619 0.677275293 0.794540164 0.852270683 1.115387321 0.878980212 1 11.98190292 -4.200223698 1.738025846 0.751935158 1.277878196 0.45129306 0.123165476 1.131174156 2.952039529 0.025325832 1.028542161 6.31E-05 4.200223698 0.525943038 AGAAS(ph)PLNS(ph)PLSSAVPSLGK ddPTM_HeLa_Curcumin_4h_R1 2 AGAASPLNSPLSSAVPSLGK 20 0 E7EPJ7;O75962-5;O75962-4;O75962 E7EPJ7 TRIO Triple functional domain protein 2 0 AGAAS(0.559)PLNS(0.743)PLS(0.515)S(0.117)AVPS(0.067)LGK;AGAAS(1)PLNS(0.993)PLS(0.006)S(0.001)AVPSLGK ; 179.41 3.80E-07 27172000 2509.75 2364.27 2473.98 2513.92 2757.78 3364.81 3571.9 5576.5 2299.91 1829.36 TRUE FALSE FALSE 2311.100639 2568.626964 2565.667875 2503.518065 2724.895275 2666.910477 3672.117901 7276.749179 2047.615627 1892.930124 1.220911755 1.356958153 1.355394921 1.322562325 1.439511813 1.408879516 1.93991202 3.844172105 1.081717493 1 10.88640544 -1.876667186 0.877120847 1.161959033 199.9999964 0.97096897 0.133968944 17.75554867 0.233585129 0.025931664 6823.275942 0.013284121 1.876667186 198.8380374 up TASESISNLS(ph)EAGS(ph)IKKGER ddPTM_HeLa_Curcumin_4h_R1 1 TASESISNLSEAGSIKKGER 20 2 F5H1T5;F5H6A0;J3KP58;P30622-2;P30622-1;P30622 F5H1T5 CLIP1 CAP-Gly domain-containing linker protein 1 2 0 TASES(0.002)IS(0.015)NLS(0.982)EAGS(0.999)IKKGER 55.634 0.0099171 15487000 4173.1 3494.6 4324.1 4060 3906.1 5949.9 5364.6 4808.5 5314.6 4966.4 TRUE FALSE FALSE 3842.794732 3796.657652 4484.35495 4043.200796 3859.522309 4715.823671 5515.116238 6274.589514 4731.601676 5138.98203 0.74777353 0.738795666 0.872615417 0.78677076 0.751028567 0.917657163 1.073192357 1.220979073 0.920727422 1 12.32726689 -4.631608099 2.223491371 0.851621793 1.215889276 0.708365962 0.081650247 0.204477706 1.792972589 0.015933369 0.107864497 2.34E-05 4.631608099 0.364267483 TASESISNLSEAGS(ph)IK ddPTM_HeLa_Curcumin_4h_R1 2 TASESISNLSEAGSIK 16 0 F5H1T5;F5H6A0;J3KP58;P30622-2;P30622-1;P30622 F5H1T5 CLIP1 CAP-Gly domain-containing linker protein 1 1 0 TASESISNLS(0.008)EAGS(0.992)IK;TASESISNLS(0.012)EAGS(0.988)IK ; 257.46 2.13E-40 212018000 9486.1 8144 9160.8 8115.2 10777.2 10476.5 9309.6 7241 9229.2 6946.8 TRUE FALSE FALSE 8735.265175 8847.931071 9500.307307 8081.621453 10648.68893 8303.555806 9570.80232 9448.747567 8216.77985 7188.200783 1.215222757 1.230896484 1.321653025 1.124289888 1.481412282 1.155164701 1.33146007 1.314480195 1.143092701 1 12.81141499 -9.053920542 0.323983656 0.898409759 1.312827532 0.367284757 0.10262493 1.477229348 0.23196811 0.229188683 0.045646051 8.83E-10 9.053920542 0.414417772 TASESISNLSEAGS(ph)IKK ddPTM_HeLa_Curcumin_4h_R1 1 TASESISNLSEAGSIKK 17 1 F5H1T5;F5H6A0;J3KP58;P30622-2;P30622-1;P30622 F5H1T5 CLIP1 CAP-Gly domain-containing linker protein 1 1 0 TASESISNLS(0.001)EAGS(0.999)IKK 90.978 0.0018207 40755000 1522.3 1672.7 1850 1789.1 1880.6 2096 1872.8 1539.1 1804.5 1512.3 TRUE FALSE FALSE 1401.808349 1817.280735 1918.562627 1781.697178 1858.175073 1661.265973 1925.345728 2008.364505 1606.550865 1564.852312 0.895808721 1.161311339 1.226034311 1.138572097 1.187444373 1.061611987 1.23036897 1.283421118 1.026646957 1 10.61181079 -7.217717215 7.341127028 0.950837679 1.181690137 0.681271043 0.065231686 0.098191125 14.32440633 0.011127743 0.013590353 6.06E-08 7.217717215 0.230852458 TASESISNLSEAGS(ph)IKKGER ddPTM_HeLa_Curcumin_4h_R1 2 TASESISNLSEAGSIKKGER 20 2 F5H1T5;F5H6A0;J3KP58;P30622-2;P30622-1;P30622 F5H1T5 CLIP1 CAP-Gly domain-containing linker protein 1 1 0 TASESISNLS(0.027)EAGS(0.973)IKKGER;TASESISNLS(0.109)EAGS(0.891)IKKGER ; 80.786 0.0018828 118670000 5129.8 3855.3 4043.5 4114 3613.02 5845.1 4292.49 3613.66 6787.8 4683.1 TRUE FALSE FALSE 4723.770917 4188.534953 4193.355667 4096.977358 3569.937096 4632.760372 4412.925717 4715.448299 6043.195322 4845.837376 0.974810038 0.864357309 0.865352124 0.845463238 0.736701796 0.956028858 0.910663189 0.97309256 1.247089998 1 12.24253027 -7.31993564 4.539655003 0.988973612 0.875626865 0.358270784 0.102218649 0.15937253 6.771339335 0.010923805 0.012546455 4.79E-08 7.31993564 -0.113346747 TASETRS(ph)EGSEYEEIPK ddPTM_HeLa_Curcumin_4h_R1 1 TASETRSEGSEYEEIPK 17 1 P48634 P48634 PRRC2A Protein PRRC2A 1 0 TAS(0.002)ET(0.012)RS(0.775)EGS(0.205)EY(0.005)EEIPK 77.668 0.0048321 15781000 2417.6 1274.6 2290.3 2257.1 2066.8 2214.7 1166.6 1022.6 1963.6 1797.7 TRUE FALSE FALSE 2226.244409 1384.770744 2375.180533 2247.760718 2042.15476 1755.346255 1199.331656 1334.386033 1748.197993 1860.169941 1.196796249 0.744432384 1.276862119 1.208363101 1.097832362 0.943648328 0.644743058 0.717346304 0.939805527 1 10.86121871 -4.927149861 3.11271676 1.090654721 0.678401144 0.511844842 0.146770282 0.133938284 2.592319928 0.020172921 0.070853961 1.18E-05 4.927149861 -0.412253577 TASFSESR ddPTM_HeLa_Curcumin_4h_R1 1 TASFSESR 8 0 P53396;P53396-2;P53396-3 P53396 ACLY ATP-citrate synthase 0 0 116.9 0.0091748 0 3873.1 3578.4 3473.9 3649.3 3936.9 4050.9 4043.7 2510.8 3657.1 4055.5 FALSE FALSE TRUE 3566.540048 3887.700951 3602.64579 3634.200164 3889.955039 3210.697677 4157.155339 3276.331362 3255.92528 4196.428323 0.849898955 0.92643092 0.858502877 0.866022218 0.926968064 0.76510247 0.990641331 0.780742839 0.775880113 1 12.03494622 -9.382924967 0.775956015 1.013031685 0.871622739 0 0.094517839 0.660734159 0.602816419 0.061372527 0.011088239 4.14E-10 9.382924967 -0.141408946 TASGSSVTS(ph)LDGTR ddPTM_HeLa_Curcumin_4h_R1 1 TASGSSVTSLDGTR 14 0 Q92597;E5RJY1;E7ESM1;Q92597-3;Q92597-2 Q92597 NDRG1 Protein NDRG1 1 0 TASGSSVT(0.002)S(0.998)LDGTR 228.17 2.31E-20 56423000 3968.8 3060.3 3085.6 3123.7 3332.5 2891.1 2071.5 1891 3319.4 2773.8 TRUE FALSE FALSE 3654.665292 3324.818696 3199.95505 3110.774957 3292.762114 2291.453271 2129.620715 2467.557195 2955.270125 2870.189344 1.273318536 1.15839699 1.114893363 1.08382221 1.147228186 0.798363103 0.741979173 0.859719308 1.029642916 1 11.4869302 -5.259202058 24.03684074 1.130574398 0.79421635 0.780785518 0.076244602 49.64548263 533360.6745 0.014779935 0.035756446 5.51E-06 5.259202058 -0.336358048 TASIS(ph)SSPS(ph)EGTPTVGS(ph)YGCTPQSLPK ddPTM_HeLa_Curcumin_4h_R1 1 TASISSSPSEGTPTVGSYGCTPQSLPK 27 0 Q6PKG0;Q6PKG0-3 Q6PKG0 LARP1 La-related protein 1 3 0 T(0.27)AS(0.091)IS(0.552)S(0.068)S(0.139)PS(0.424)EGT(0.423)PT(0.035)VGS(0.654)Y(0.006)GCT(0.336)PQS(0.004)LPK 107.13 3.38E-08 8873800 2748.3 2591.9 2433.2 2904.7 2161.3 2843.5 2087.4 1231.8 2956.8 2620.1 TRUE FALSE FALSE 2530.769155 2815.932287 2523.376532 2892.681121 2135.527909 2253.726047 2145.966826 1607.370149 2632.446438 2711.14828 0.933467628 1.038649309 0.930740879 1.066957917 0.787683922 0.831280998 0.791534289 0.592874304 0.97097103 1 11.4046883 -3.64462503 0.564793232 0.97789587 0.026577939 0.783631851 0.063662721 2.177384018 0.287957173 0.011538633 1.588774412 0.00022666 3.64462503 -0.951317931 TASLS(ph)NQECQLYPR ddPTM_HeLa_Curcumin_4h_R1 1 TASLSNQECQLYPR 14 0 Q9Y675 Q9Y675 SNURF SNRPN upstream reading frame protein 1 0 T(0.004)AS(0.248)LS(0.748)NQECQLYPR 198.29 1.36E-30 0 950.74 706.47 858.12 968.48 962.46 1305.7 688.32 616.4 1136.1 944.72 TRUE FALSE FALSE 875.4879258 767.5341188 889.9226821 964.4726864 950.9832931 1034.883102 707.6324067 804.3375224 1011.472672 977.5489497 0.895594974 0.785161827 0.910361248 0.986623418 0.972824219 1.058650927 0.723884371 0.822810482 1.034702838 1 9.933025135 TASPPGPPPYGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 TASPPGPPPYGKR 13 1 P54259 P54259 ATN1 Atrophin-1 0 1 ; TASPPGPPPYGK(1)R;TASPPGPPPYGK(1)R 114.89 0.00034398 5961500 2934.9 3140.2 2474.3 2687.2 2775.7 2874.4 2866.3 3352.9 2740.3 3471 FALSE TRUE FALSE 2702.599568 3411.624896 2565.999735 2676.081078 2742.60159 2278.217039 2946.720664 4375.183775 2439.695946 3591.616992 0.752474324 0.949885498 0.714441362 0.745090884 0.763611932 0.634315141 0.820444015 1.218165463 0.679275087 1 11.81041779 -9.414204214 1.007301517 1.006159672 0.808762427 0 0.182848112 0.815821601 1.404038266 0.121234572 0.027034404 3.85E-10 9.414204214 -0.197397246 TASPPPPPKR ddPTM_HeLa_Curcumin_4h_R1 1 TASPPPPPKR 10 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 0 0 120.99 0.0064403 3309700 1240.9 877.58 961.99 1008.3 1085.9 1292.1 1134.5 1408.3 1208.9 1176.4 FALSE FALSE TRUE 1142.681456 953.4341048 997.6421957 1004.127922 1072.951352 1024.103895 1166.331017 1837.684187 1076.286695 1217.279812 0.938717166 0.783249747 0.819566862 0.82489491 0.88143362 0.841305248 0.95814537 1.509664556 0.884173617 1 10.24944512 -4.263576029 4.893610896 0.9217399 1.539685593 0.861512293 0.074138016 0.058780821 4.175008913 0.012952703 0.122679831 5.45E-05 4.263576029 0.617945692 VS(ph)PDFTQESR ddPTM_HeLa_Curcumin_4h_R1 1 VSPDFTQESR 10 0 D6RE87;E7EPB1;E7EQS8;Q6N021-2;Q6N021-3;Q6N021 D6RE87 TET2 Methylcytosine dioxygenase TET2 1 0 VS(0.997)PDFT(0.003)QESR 130.69 0.0028228 10305000 1955.4 1533.8 1715 1801.1 1612.9 1548.4 1347.8 562.95 2016.4 1808 TRUE FALSE FALSE 1800.628027 1666.374838 1778.559409 1793.647525 1593.667221 1227.244386 1385.615641 734.5908635 1795.205965 1870.827865 0.962476591 0.890715211 0.950680413 0.958745355 0.851851338 0.655990008 0.740643042 0.392655507 0.959578376 1 10.86946111 -4.092889521 0.555299868 0.982007613 4.11E-17 0.890618924 0.059867884 0.887261668 0.162108743 0.010671948 0.584137813 8.07E-05 4.092889521 -0.982007613 down TASRPDDIPDS(ph)PSSPK ddPTM_HeLa_Curcumin_4h_R1 2 TASRPDDIPDSPSSPK 16 1 Q5VZK9;Q5VZK9-2;A0A0U1RQQ1 Q5VZK9 LRRC16A Leucine-rich repeat-containing protein 16A 1 0 T(0.008)AS(0.288)RPDDIPDS(0.69)PS(0.013)S(0.002)PK;TASRPDDIPDS(0.989)PS(0.002)S(0.008)PK ; 193.27 2.86E-06 12923800 3012.5 2514.2 2784.5 2782.3 3001.7 3557.9 2467.03 1761.77 3189.9 3292.1 TRUE FALSE FALSE 2774.057446 2731.516245 2887.696019 2770.78758 2965.906688 2819.951434 2536.248222 2298.925563 2839.975951 3406.50023 0.814342363 0.80185412 0.847701695 0.813382473 0.870660939 0.827814837 0.744531939 0.67486435 0.833693163 1 11.73407459 -13.52287875 0.151059532 1.751398513 0.731235197 0.247860959 0.068871621 26.53012788 0.272597332 5.907769167 0.115426223 3.00E-14 13.52287875 -1.020163316 TASRPDDIPDSPS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 2 TASRPDDIPDSPSSPK 16 1 Q5VZK9;Q5VZK9-2;A0A0U1RQQ1 Q5VZK9 LRRC16A Leucine-rich repeat-containing protein 16A 1 0 T(0.008)AS(0.031)RPDDIPDS(0.364)PS(0.588)S(0.009)PK;TASRPDDIPDS(0.074)PS(0.895)S(0.031)PK ; 109.32 0.00073406 52345000 7555 5483.3 7085.6 7558.5 7351.2 8822.3 8011.6 7721.2 8410.5 6913.1 TRUE FALSE FALSE 6957.013778 5957.252019 7348.198569 7527.22493 7263.541741 6992.455532 8236.383934 10075.35834 7487.889192 7153.32971 0.972556007 0.832794273 1.0272417 1.052268696 1.015407095 0.977510588 1.151405607 1.408485103 1.046769756 1 12.80439922 -4.324186533 1.824705983 0.983604831 1.515712851 0.822329223 0.059823447 0.206269782 0.76269532 0.008129166 0.179224393 4.74E-05 4.324186533 0.53210802 YDERPGPS(ph)PLPHR ddPTM_HeLa_Curcumin_4h_R1 2 YDERPGPSPLPHR 13 1 P08621;P08621-4 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 1 0 Y(0.007)DERPGPS(0.993)PLPHR;YDERPGPS(1)PLPHR ; 88.108 0.0062411 1300210000 7717.8 6642.9 6822.6 7320.6 6714.1 6490.3 5624.3 2054.6 7076.8 6129.2 TRUE FALSE FALSE 7106.927986 7217.082676 7075.451558 7290.309297 6634.038743 5144.138619 5782.102721 2681.038082 6300.492745 6342.189244 1.120579616 1.137948175 1.115616593 1.149494128 1.046017154 0.811098254 0.911688772 0.422730697 0.993425535 1 12.63076521 -4.092591114 0.99089326 1.073938734 1.21E-12 0.842359827 0.083253061 0.745774594 0.452073754 0.013138536 0.919104681 8.08E-05 4.092591114 -1.073938734 down TASTPTPPQT(ph)GGGLEPQANGETPQVAVIVRPDDR ddPTM_HeLa_Curcumin_4h_R1 1 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDR 34 1 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6;C9JF13;C9J6B6;C9JSU8;C9J556;C9K073;C9J2Z7;C9JWW9;C9JWH7 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 0 T(0.002)AS(0.01)T(0.023)PT(0.181)PPQT(0.473)GGGLEPQANGET(0.311)PQVAVIVRPDDR 49.09 0.0091614 178550000 1147.2 717.88 958.43 1122.5 1101.9 1011.7 533.27 401.78 801.44 938.34 TRUE FALSE FALSE 1056.397909 779.9303484 993.9502589 1117.855392 1088.760562 801.8620158 548.232121 524.2808724 713.5240371 970.9472452 1.088007525 0.803267482 1.023691312 1.151303944 1.121338536 0.82585539 0.564636363 0.539968443 0.734874156 1 9.923249101 -4.925517539 2.895651121 1.035318816 0.544068342 0.622856462 0.13097339 0.07884506 1.317411138 0.013429689 0.048655191 1.19E-05 4.925517539 -0.491250474 TATCHSSS(ph)SPPIDAASAEPYGFR ddPTM_HeLa_Curcumin_4h_R1 1 TATCHSSSSPPIDAASAEPYGFR 23 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 TATCHSSS(0.965)S(0.035)PPIDAASAEPYGFR 138.57 7.34E-06 148770000 989.26 724.56 512.51 854.47 1305.8 2200.8 819.75 829.45 1042.6 961.03 TRUE FALSE FALSE 910.9590271 787.1877378 531.5040714 850.9344295 1290.229188 1744.329272 842.7499788 1082.345487 928.2293885 994.425721 0.916065431 0.791600339 0.534483431 0.855704364 1.297461601 1.754107155 0.847474036 1.088412602 0.933432602 1 9.957719802 -5.760969648 24.99994077 0.903346363 1.254567712 0.382099622 0.246158093 12.14266766 646184.2337 0.037570911 0.071626941 1.73E-06 5.760969648 0.351221349 TATDEAYKDPSNLQGK ddPTM_HeLa_Curcumin_4h_R1 1 TATDEAYKDPSNLQGK 16 1 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 101.72 0.00080539 0 2686.8 1910.9 2123.2 2016.9 2625.6 3455.1 2149.2 1742 2417 2162 FALSE FALSE TRUE 2474.136945 2076.069681 2201.88766 2008.554602 2594.291435 2738.473313 2209.500768 2273.127781 2151.861147 2237.129339 1.105942737 0.928006104 0.984246919 0.897826767 1.159651965 1.22410147 0.987649989 1.016091355 0.961884997 1 11.12743295 TATDS(ph)DERIDDEIDTEVEETQEEK ddPTM_HeLa_Curcumin_4h_R1 2 TATDSDERIDDEIDTEVEETQEEK 24 1 A0A0C4DGZ1;Q8N5P1 A0A0C4DGZ1 ZC3H8 Zinc finger CCCH domain-containing protein 8 1 0 T(0.024)AT(0.079)DS(0.897)DERIDDEIDTEVEETQEEK;T(0.055)AT(0.055)DS(0.835)DERIDDEIDT(0.055)EVEETQEEK ; 108.28 1.36E-06 46550000 2465.9 2004.57 2167.5 2370.02 1998.56 2499.36 2008.07 1165.7 2414.91 2172.07 TRUE FALSE FALSE 2270.721413 2177.836099 2247.829457 2360.213485 1974.728477 1980.964562 2064.41104 1521.116564 2150.000415 2247.549271 1.01030996 0.968982583 1.000124663 1.050127584 0.878614099 0.881388714 0.918516478 0.676788973 0.956597679 1 11.13413703 -3.335974754 0.595148231 1.004243557 6.85E-14 0.773380992 0.048079224 2.666918979 0.28974054 0.007739348 2.374571558 0.000461344 3.335974754 -1.004243557 TATESFASDPILYR ddPTM_HeLa_Curcumin_4h_R1 2 TATESFASDPILYR 14 0 P14618;P14618-3;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 113.69 0.00087364 3455800 1859.49 1449.24 1699.9 1917.42 2223.05 1232.38 1355.27 1093.02 1679.35 1440.96 FALSE FALSE TRUE 1712.309404 1574.505848 1762.899789 1909.486224 2196.541581 976.7704962 1393.295229 1426.276766 1495.129507 1491.033253 1.148404572 1.055983054 1.182334322 1.280646304 1.4731674 0.655096387 0.934449467 0.956569388 1.002747259 1 10.54209672 -5.238255109 24.99934866 1.118589243 0.857279562 0.44142181 0.156535839 702.009735 756968.37 0.023170573 0.059032993 5.78E-06 5.238255109 -0.261309681 TATESFASDPILYRPVAVALDTK ddPTM_HeLa_Curcumin_4h_R1 2 TATESFASDPILYRPVAVALDTK 23 1 P14618;P14618-3;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 148.2 4.80E-06 108231000 3642.7 3502.1 3916.5 2838.4 3504.7 5837.1 4124.2 4253.2 3864.7 3822.1 FALSE FALSE TRUE 3354.376451 3804.805919 4061.648935 2826.655453 3462.908741 4626.419662 4239.913952 5549.981101 3440.752079 3954.917691 0.84815329 0.962044274 1.02698697 0.714719161 0.875595654 1.169789114 1.072061237 1.403311405 0.869993347 1 11.94943195 -4.207120735 1.036440917 0.920891556 1.656230731 0.672080318 0.104864327 0.967648813 0.7500174 0.016635647 0.805216156 6.21E-05 4.207120735 0.735339175 TATESFASDPILYRPVAVALDTKGPEIR ddPTM_HeLa_Curcumin_4h_R1 2 TATESFASDPILYRPVAVALDTKGPEIR 28 2 P14618;P14618-3;P14618-2;H3BTN5;H3BQ34;H3BUW1;H3BTJ2;H3BT25 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 75.054 4.57E-05 30432000 3918.5 2564.67 2825.99 2622.71 2290.37 6173 3181.01 4236.1 4904.6 4152.2 FALSE FALSE TRUE 3608.34659 2786.348647 2930.723675 2611.857921 2263.058834 4892.650216 3270.260579 5527.667389 4366.577651 4296.488641 0.839836176 0.648517634 0.682120662 0.607905231 0.526722871 1.138755534 0.761147265 1.286554638 1.016313091 1 12.06894237 TATNNASSSCQST(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 TATNNASSSCQSTPR 15 0 Q92833-2;Q92833-3;Q92833 Q92833-2 JARID2 Protein Jumonji 1 0 TATNNASSSCQS(0.003)T(0.997)PR 219.53 5.40E-14 2289400 510.57 564.69 588.26 777.19 599.69 787.27 475.4 142.69 806.88 537.26 TRUE FALSE FALSE 470.1578457 613.4992874 610.0614331 773.9741937 592.5390884 623.9813276 488.7384445 186.1955241 718.3672827 555.929745 0.845714499 1.103555427 1.097371455 1.392215834 1.065852464 1.1224104 0.879137065 0.334926357 1.292190765 1 9.118758765 -4.285108853 3.326543333 1.004131325 0.262067724 0.608940775 0.172134201 0.163633552 2.99405053 0.024323376 0.299044143 5.19E-05 4.285108853 -0.742063601 TATPEIVDNKDGTVTVR ddPTM_HeLa_Curcumin_4h_R1 2 TATPEIVDNKDGTVTVR 17 1 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 111.81 0.00066463 9975300 3099 2797.1 2540.6 2840.6 2588.4 3957.3 3299.2 3157.7 3349.5 3184.5 FALSE FALSE TRUE 2853.71088 3038.86886 2634.756871 2828.84635 2557.535021 3136.511372 3391.766673 4120.468194 2982.06823 3295.161138 0.866030753 0.922221625 0.79958362 0.858484982 0.776148696 0.951853715 1.029317393 1.250460303 0.904984037 1 11.6861333 -4.340372647 1.940772835 0.907972065 1.319380694 0.743164893 0.065718372 0.327081362 1.45957762 0.011738039 0.226106556 4.57E-05 4.340372647 0.41140863 TATPQQAQEVHEK ddPTM_HeLa_Curcumin_4h_R1 2 TATPQQAQEVHEK 13 0 P60174;P60174-3;P60174-4;U3KPZ0 P60174 TPI1 Triosephosphate isomerase 0 0 ; ; 151.74 5.29E-05 13711600 7454.2 5777.9 7691.5 6690.7 5845.6 8457.1 7105.5 7543.6 7812.6 8006.8 FALSE FALSE TRUE 6864.192204 6277.31593 7976.553756 6663.015656 5775.895038 6703.002129 7304.861207 9843.608914 6955.577326 8285.035704 0.828504843 0.757669146 0.962766371 0.804222926 0.697147875 0.809049275 0.881693389 1.18811907 0.839534985 1 13.0162922 -9.275266606 1.008596548 0.999829151 0.855739546 0 0.136597529 0.830601035 1.517564215 0.084922434 0.023135232 5.31E-10 9.275266606 -0.144089605 TATSLPVVNFGS(ph)PLR ddPTM_HeLa_Curcumin_4h_R1 2 TATSLPVVNFGSPLR 15 0 Q96T17;Q96T17-2;Q96T17-5;Q96T17-4 Q96T17 MAP7D2 MAP7 domain-containing protein 2 1 0 TATSLPVVNFGS(1)PLR;TATSLPVVNFGS(1)PLR ; 163.02 0.00027213 44181000 2115.01 1857.36 1878.1 2016.31 2263.63 3566 2404.2 535.26 2393.54 1825.6 TRUE FALSE FALSE 1947.604727 2017.901922 1947.704038 2007.967043 2236.637691 2826.371403 2471.655381 698.45831 2130.97465 1889.039464 1.031002668 1.068215863 1.03105524 1.062956641 1.184007922 1.496195001 1.308419135 0.369742572 1.128073124 1 10.88343713 -5.96627947 4.959877605 1.021831765 1.134075262 0 0.276115195 0.604019617 36.78400878 0.038986336 0.070795962 1.08E-06 5.96627947 0.112243497 TATSLPVVNFGS(ph)PLRR ddPTM_HeLa_Curcumin_4h_R1 2 TATSLPVVNFGSPLRR 16 1 Q96T17;Q96T17-2;Q96T17-5;Q96T17-4 Q96T17 MAP7D2 MAP7 domain-containing protein 2 1 0 TATSLPVVNFGS(1)PLRR;TATSLPVVNFGS(1)PLRR ; 69.986 0.011793 180890000 6249.9 5180.3 5818 5185.5 5084 7787.3 5965.8 2565.49 6882.5 5317.1 TRUE FALSE FALSE 5755.21382 5628.062049 6033.620198 5164.043775 5023.37662 6172.126199 6133.184292 3347.696091 6127.506969 5501.868829 1.046047079 1.022936428 1.096649227 0.938598126 0.913030968 1.121823582 1.11474564 0.608465268 1.113713751 1 12.42570603 -4.253908582 24.98075079 1.025753962 0.608465066 0.764150659 0.071622341 310.6564406 1030467.737 0.009054781 0.127416592 5.57E-05 4.253908582 -0.417288896 LGDVS(ph)PTQIDVSQFGSFK ddPTM_HeLa_Curcumin_4h_R1 2 LGDVSPTQIDVSQFGSFK 18 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 LGDVS(0.993)PT(0.007)QIDVSQFGSFK;LGDVS(0.997)PT(0.003)QIDVSQFGSFK ; 264.01 1.58E-53 201757000 7568.5 6964 7636.9 7395.1 9191.1 7663.5 7868.2 9992.5 5775.3 5532.3 TRUE FALSE FALSE 6969.445239 7565.937129 7919.930232 7364.501036 9081.502135 6074.003715 8088.960516 13039.16725 5141.764039 5724.547013 1.217466679 1.321665646 1.383503396 1.286477518 1.586414107 1.061045302 1.413030672 2.277764026 0.898195792 1 12.48294582 -1.872061297 1.057736572 1.174462718 199.9999999 0.718354136 0.195278695 113.7890839 0.91020887 0.030444095 53958.74478 0.013425755 1.872061297 198.8255372 up TAVCDIPPR ddPTM_HeLa_Curcumin_4h_R1 3 TAVCDIPPR 9 0 Q5JP53;P07437;Q5ST81;A0A075B736;Q5SQY0;A6NNZ2;P04350;P68371;Q3ZCM7;Q9BVA1;Q13885 Q5JP53;P04350;P68371;Q9BVA1 TUBB;TUBB8;TUBB4A;TUBB4B;TUBB2B;TUBB2A Tubulin beta chain;Tubulin beta-8 chain-like protein LOC260334;Tubulin beta-4A chain;Tubulin beta-4B chain;Tubulin beta-8 chain;Tubulin beta-2B chain;Tubulin beta-2A chain 0 0 ;; ;; 104.44 0.003505 9872400 13440.8 11872.3 12313.3 12375.5 11382.5 13247.1 10312.4 9872.3 14001 12183.4 FALSE FALSE TRUE 12376.9465 12898.48871 12769.64173 12324.29346 11246.77112 10499.50213 10601.73819 12882.31882 12465.12533 12606.77224 0.98176966 1.023139663 1.012919206 0.977593092 0.892121386 0.832846182 0.840955796 1.021857029 0.98876422 1 13.62191132 -5.798443395 4.304557595 0.995419731 0.887567243 0.495553171 0.04956095 0.12211061 4.950960543 0.006967815 0.013359354 1.59E-06 5.798443395 -0.107852488 TAVETAVLLLR ddPTM_HeLa_Curcumin_4h_R1 2 TAVETAVLLLR 11 0 P49368;B4DUR8;P49368-2 P49368 CCT3 T-complex protein 1 subunit gamma 0 0 ; ; 136.57 0.00034776 825160 134.26 0 52.209 0 0 53.252 63.938 0 0 0 FALSE FALSE TRUE 123.6331793 0 54.14391147 0 0 42.20693493 65.7319282 0 0 0 0 TAVIPINGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 TAVIPINGSPR 11 0 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 0 TAVIPINGS(1)PR;TAVIPINGS(1)PR;TAVIPINGS(1)PR ;; 124.47 0.0036173 103989000 18497.9 15815.2 16720.7 17894.4 15987.6 18409.5 15583.3 6870.7 17507.1 16570 TRUE FALSE FALSE 17033.7717 17182.19542 17340.38385 17820.35771 15796.95831 14591.16218 16020.52546 8965.544801 15586.61493 17145.80627 0.993465774 1.002122335 1.011348407 1.039342066 0.921330736 0.851004727 0.93436991 0.522900158 0.909062816 1 14.06556813 -3.895156487 1.104422682 0.995268553 8.62E-32 0.831534792 0.058606365 0.794948568 0.451909671 0.007297042 1.1163992 0.000127304 3.895156487 -0.995268553 TAVPPLSEGDGYS(ph)SENTSR ddPTM_HeLa_Curcumin_4h_R1 2 TAVPPLSEGDGYSSENTSR 19 0 Q9BYW2;H7C3H4;A0A1W2PPX9 Q9BYW2 SETD2 Histone-lysine N-methyltransferase SETD2 1 0 TAVPPLSEGDGYS(0.497)S(0.497)ENT(0.006)SR;TAVPPLSEGDGYS(0.462)S(0.462)ENT(0.052)S(0.024)R ; 233.65 2.62E-25 23605000 10827.6 8696.5 8889.1 9587.2 9506.8 10980.3 7494.9 4491.9 10958.2 8843 TRUE FALSE FALSE 9970.584035 9448.186709 9218.537866 9547.530707 9393.437619 8702.862007 7705.186723 5861.459632 9756.112876 9150.293592 1.089646352 1.03255558 1.007458151 1.043412499 1.026572265 0.951101942 0.84206989 0.640576127 1.066207633 1 13.15960232 -4.204098779 1.028997592 1.041021628 0.395838798 0.962773373 0.024680039 0.354256921 0.2690701 0.00526215 0.257426453 6.25E-05 4.204098779 -0.645182831 TAVPS(ph)PVEAAAASDPAAAR ddPTM_HeLa_Curcumin_4h_R1 2 TAVPSPVEAAAASDPAAAR 19 0 Q147X3;J3KNC2;Q147X3-2 Q147X3 NAA30 N-alpha-acetyltransferase 30 1 0 T(0.141)AVPS(0.859)PVEAAAASDPAAAR;T(0.031)AVPS(0.969)PVEAAAASDPAAAR ; 235.79 1.13E-25 68621300 7365.7 6158.7 6276.8 6426.7 5952 7598.2 5770 4042.8 8262.6 6184.8 TRUE FALSE FALSE 6782.697073 6691.030585 6509.42373 6400.108018 5881.026287 6022.247671 5931.890671 5275.431109 7356.213452 6399.72134 1.059842564 1.045519052 1.017141745 1.000060421 0.918950369 0.941017171 0.926898275 0.824322002 1.1494584 1 12.64379337 -4.932432238 0.660184711 1.03090103 0.814416582 0.703395789 0.0465877 0.553151807 0.270550186 0.006064696 0.075907931 1.17E-05 4.932432238 -0.216484448 TAVVVGTITDDVR ddPTM_HeLa_Curcumin_4h_R1 2 TAVVVGTITDDVR 13 0 F8VYV2;A0A075B7A0;G3V203;H0YHA7;J3QQ67;Q07020-2;Q07020;F8VUA6 F8VYV2 RPL18 60S ribosomal protein L18 0 0 ; ; 183.03 8.08E-09 6653900 1928.7 1771.18 1637.15 1983.58 1880.19 1863.12 1584.97 1648.77 1965.73 1877.31 FALSE FALSE TRUE 1776.04136 1924.272907 1697.824219 1975.372472 1857.769962 1476.68791 1629.439992 2151.472383 1750.094337 1942.546383 0.914285175 0.99059303 0.874019912 1.016898484 0.956358097 0.760181545 0.838816518 1.107552644 0.900927953 1 10.92373333 -10.99086275 0.327285731 1.118412651 0.919393364 0 0.097255796 20.26083966 1.147805525 1.733979981 0.036178035 1.02E-11 10.99086275 -0.199019287 TCEERPAEDGS(ph)DEEDPDSMEAPTR ddPTM_HeLa_Curcumin_4h_R1 4 TCEERPAEDGSDEEDPDSMEAPTR 24 1 D6RGJ8;Q9H6Y2 D6RGJ8 WDR55 WD repeat-containing protein 55 1 0 TCEERPAEDGS(0.967)DEEDPDS(0.025)MEAPT(0.008)R;TCEERPAEDGS(0.999)DEEDPDS(0.001)MEAPTR;T(0.064)CEERPAEDGS(0.935)DEEDPDS(0.001)MEAPTR;TCEERPAEDGS(1)DEEDPDSMEAPTR ;;; 97.813 1.02E-05 311502000 10631.1 7958.94 8227.9 9361.8 9837.7 10810.6 8400.1 6989.68 10664.5 8856.8 TRUE FALSE FALSE 9789.637217 8646.875309 8532.833212 9323.063352 9720.391853 8568.359699 8635.784198 9120.801255 9494.631031 9164.573141 1.068204385 0.943510972 0.931067174 1.017293791 1.06064862 0.934943676 0.942300756 0.995223794 1.03601454 1 13.16185197 -7.258940288 24.99569646 1.032207626 0.975431553 0.299548796 0.041806412 238.4450291 2384912.896 0.007934525 0.009469167 5.51E-08 7.258940288 -0.056776073 TCELPPS(ph)QTQPSR ddPTM_HeLa_Curcumin_4h_R1 1 TCELPPSQTQPSR 13 0 Q5VZ46-2;Q5VZ46 Q5VZ46-2 KIAA1614 Uncharacterized protein KIAA1614 1 0 TCELPPS(0.998)QT(0.002)QPSR 104.52 0.0052215 18119000 718.42 705.71 633.39 667.09 492.34 804.32 473.05 650.65 975.34 850.6 TRUE FALSE FALSE 661.5562989 766.7084278 656.8639906 664.3297583 486.4691671 637.4949654 486.3225099 849.0301898 868.3476422 880.1582867 0.751633324 0.871102891 0.746302115 0.754784416 0.552706456 0.724295817 0.55253983 0.964633524 0.986581227 1 9.78161919 -9.491301564 0.323727933 1.137186018 0.694429847 0.441802192 0.116093646 2.643049635 0.32361864 0.436149896 0.054474046 3.23E-10 9.491301564 -0.44275617 TCFS(ph)PNRVIGLSSDLQQVGGASAR ddPTM_HeLa_Curcumin_4h_R1 2 TCFSPNRVIGLSSDLQQVGGASAR 24 1 O00303 O00303 EIF3F Eukaryotic translation initiation factor 3 subunit F 1 0 T(0.217)CFS(0.783)PNRVIGLSSDLQQVGGASAR;T(0.483)CFS(0.517)PNRVIGLSSDLQQVGGASAR ; 92.565 1.86E-05 67087000 1396.37 753.21 1114.22 1176.38 655.63 1383.13 1128.08 926.47 1277.87 1023.93 TRUE FALSE FALSE 1285.845841 818.3141162 1155.513973 1171.512451 647.8120405 1096.253247 1159.730889 1208.946438 1137.690858 1059.511491 1.21362142 0.772350393 1.090610138 1.10571 0.611425214 1.034678015 1.094590194 1.141041365 1.073788125 1 10.04918352 -7.298707101 24.9573246 1.100876764 0.980316333 0.095332193 0.165132181 1012.941602 678340.876 0.02950602 0.033741856 5.03E-08 7.298707101 -0.120560431 TCGVNDDES(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 TCGVNDDESPSK 12 0 Q8NG08 Q8NG08 HELB DNA helicase B 1 0 TCGVNDDES(0.59)PS(0.41)K;TCGVNDDES(0.922)PS(0.078)K ; 177.93 8.75E-10 3002300 4697.4 4220.1 4472.8 4195.3 5219.8 4852.7 3961.1 3351.3 3938.6 4298.7 TRUE FALSE FALSE 4325.595833 4584.86664 4638.565903 4177.94096 5157.557294 3846.195319 4072.237805 4373.095943 3506.545434 4448.079505 0.972463695 1.030751954 1.042824414 0.939268499 1.159502048 0.864686729 0.915504725 0.983142486 0.788327958 1 12.11896686 TCNSPQNS(ph)TDSVSDIVPDSPFPGALGSDTR ddPTM_HeLa_Curcumin_4h_R1 1 TCNSPQNSTDSVSDIVPDSPFPGALGSDTR 30 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 0 T(0.026)CNS(0.259)PQNS(0.357)T(0.357)DSVSDIVPDSPFPGALGSDTR 129.04 1.38E-12 8707400 1331.4 1053.1 1124.8 1279.8 1021.7 1459.6 1113.1 815.24 1518.9 1171.6 TRUE FALSE FALSE 1226.018285 1144.125271 1166.486077 1274.504527 1009.516895 1156.862507 1144.33059 1063.802923 1352.28047 1212.313013 1.011305061 0.943754014 0.96219876 1.051299882 0.832719672 0.95426057 0.943923375 0.87749856 1.115454883 1 10.24354653 -5.965023786 0.67141394 1.004790493 0.90354642 0.366445444 0.061370113 0.656421567 0.540172485 0.009814196 0.033385865 1.08E-06 5.965023786 -0.101244073 NYGSPLISGS(ph)TPK ddPTM_HeLa_Curcumin_4h_R1 1 NYGSPLISGSTPK 13 0 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 1 0 NYGS(0.004)PLIS(0.111)GS(0.818)T(0.067)PK 190.37 3.55E-21 0 1805.5 1368.8 1599.3 1493.7 1730 1714.2 1282.5 511.67 1618.6 1494.3 TRUE FALSE FALSE 1662.59277 1487.112973 1658.571465 1487.519465 1709.37088 1358.655597 1318.483498 667.6758276 1441.04363 1546.226814 1.075258012 0.961768972 1.072657291 0.962031865 1.105511083 0.878691008 0.852710279 0.431809759 0.931974285 1 10.59453625 -4.090841697 1.217353563 1.031014839 6.72E-19 0.875586387 0.064647335 0.401000153 0.3778566 0.007857355 0.571815255 8.11E-05 4.090841697 -1.031014839 down AGVNSDS(ph)PNNCSGK ddPTM_HeLa_Curcumin_4h_R1 3 AGVNSDSPNNCSGK 14 0 F8WE62;Q9Y4C1 F8WE62 KDM3A Lysine-specific demethylase 3A 1 0 AGVNSDS(0.993)PNNCS(0.007)GK;AGVNSDS(0.975)PNNCS(0.025)GK;AGVNS(0.009)DS(0.99)PNNCSGK ;; 203.2 5.41E-09 22951600 9334.9 7297.3 8076.4 8121.2 7464.2 9382 6157.7 2653.87 8469.7 7392.1 TRUE FALSE FALSE 8596.032815 7928.046096 8375.718489 8087.596626 7375.19429 7436.067443 6330.468489 3463.022746 7540.5951 7648.974925 1.123815008 1.03648478 1.09501189 1.057343854 0.964206886 0.972165227 0.82762312 0.452743378 0.985830804 1 12.9010507 -4.08855556 1.094314421 1.057651766 3.18E-16 0.937897201 0.045743522 0.426704211 0.318291833 0.007850464 0.567837359 8.16E-05 4.08855556 -1.057651766 down TCTTVAFTQVNSEDKGALAK ddPTM_HeLa_Curcumin_4h_R1 1 TCTTVAFTQVNSEDKGALAK 20 1 P62424;Q5T8U2 P62424 RPL7A 60S ribosomal protein L7a 0 0 210.57 9.53E-20 3065400 615.33 628.93 673.4 482.6 578.06 602.59 401.04 543.46 677.17 527.86 FALSE FALSE TRUE 566.6259812 683.2919067 698.3567964 480.6031291 571.167012 477.6060414 412.2921031 709.1584522 602.8861452 546.2030957 1.037390644 1.25098505 1.278566163 0.879898215 1.045704458 0.874411085 0.754832967 1.29834206 1.103776507 1 9.093293681 TDALTSS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 2 TDALTSSPGR 10 0 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 1 0 TDALTS(0.003)S(0.997)PGR;TDALT(0.001)S(0.023)S(0.976)PGR ; 131.42 0.0027192 220510000 10225.2 11092.7 11464.7 11279.9 12404.2 11363.4 10523.5 13159.3 10064.8 9528.3 TRUE FALSE FALSE 9415.86463 12051.50356 11889.59187 11233.22676 12256.28802 9006.502748 10818.76109 17171.50999 8960.716621 9859.407716 0.955013212 1.222335449 1.205913399 1.139340931 1.243105912 0.913493286 1.097303347 1.741637073 0.908849383 1 13.26728527 -4.265937473 4.47642314 1.037799707 1.786634931 0.714471161 0.12463377 0.078963434 3.955187764 0.018539409 0.184945094 5.42E-05 4.265937473 0.748835224 TDANESSSS(ph)PEIR ddPTM_HeLa_Curcumin_4h_R1 2 TDANESSSSPEIR 13 0 Q96JM7-2;Q96JM7 Q96JM7-2 L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 1 0 TDANESS(0.001)S(0.003)S(0.996)PEIR;TDANESSS(0.035)S(0.965)PEIR ; 177.21 0.00020053 23750000 4366.1 3537.7 3362.9 3501 4101.1 4027.8 3386.9 2505.59 3408.9 3786.5 TRUE FALSE FALSE 4020.518578 3843.483024 3487.532032 3486.51379 4052.197061 3192.388877 3481.927299 3269.532857 3034.952199 3918.080593 1.026144941 0.980960685 0.890112378 0.889852495 1.034230145 0.814783872 0.888681898 0.8344731 0.774601779 1 11.93593136 -5.706886436 0.472319046 1.015856414 0.822857147 0 0.093268981 0.890770949 0.298719234 0.014729062 0.077670596 1.96E-06 5.706886436 -0.192999266 AEAPAGPALGLPS(ph)PEAESGVDR ddPTM_HeLa_Curcumin_4h_R1 3 AEAPAGPALGLPSPEAESGVDR 22 0 Q53F19 Q53F19 C17orf85 Uncharacterized protein C17orf85 1 0 AEAPAGPALGLPS(1)PEAESGVDR;AEAPAGPALGLPS(0.986)PEAES(0.014)GVDR;AEAPAGPALGLPS(0.995)PEAES(0.005)GVDR ;; 256.33 4.99E-48 76183300 4567.9 4043.84 4909.3 4690.52 5747.5 5845.5 5753.4 8385.3 4487.17 4172.52 TRUE FALSE FALSE 4206.345895 4393.371511 5091.242977 4671.111871 5678.964816 4633.077408 5914.82492 10941.93937 3994.938677 4317.514759 0.974251654 1.017569541 1.179206849 1.081898298 1.315331883 1.073088956 1.369960556 2.534314294 0.925286629 1 12.07598539 -1.857824675 0.986747165 1.021492103 200 0.939557799 0.110785472 35.48341782 0.336557546 0.017290056 15609.59037 0.013873158 1.857824675 198.9785079 up ELVEPLT(ph)PSGEAPNQALLR ddPTM_HeLa_Curcumin_4h_R1 2 ELVEPLTPSGEAPNQALLR 19 0 P00533;E9PFD7;Q504U8 P00533 EGFR Epidermal growth factor receptor;Receptor protein-tyrosine kinase 1 0 ELVEPLT(0.995)PS(0.005)GEAPNQALLR;ELVEPLT(0.981)PS(0.019)GEAPNQALLR ; 210.2 1.91E-13 43920000 4525.5 3950 5108.4 7664.3 4501.1 11106.5 7160.4 13630.3 9194.6 6288.9 TRUE FALSE FALSE 4167.3019 4291.420399 5297.721798 7632.587157 4447.427322 8802.886704 7361.301553 17786.11572 8185.975384 6507.438807 0.640390486 0.659463812 0.814102438 1.172901872 0.68343744 1.352742141 1.131213335 2.733197538 1.2579412 1 12.66787412 -1.856257474 0.943635 0.830763747 200 0.820053449 0.247828735 45.31411405 0.48232909 0.032919606 18982.67373 0.013923311 1.856257474 199.1692362 up TDASSASSFLDS(ph)DELER ddPTM_HeLa_Curcumin_4h_R1 2 TDASSASSFLDSDELER 17 0 G3XAC6;Q14498-2;Q14498;H0Y4X3;Q14498-3;A0A0U1RQW2;A0A0U1RQH7 G3XAC6 RBM39 RNA-binding protein 39 1 0 TDASSASSFLDS(1)DELER;TDASSASSFLDS(1)DELER ; 353.55 7.98E-173 19351800 3571.96 2629.26 2734.74 3068.76 3405.08 3499.09 3184.42 3146.48 3228.25 2491.88 TRUE FALSE FALSE 3289.235597 2856.521519 2836.09187 3056.062284 3364.476645 2773.339291 3273.766255 4105.827267 2874.119052 2578.472645 1.275652702 1.107834719 1.09991156 1.185221915 1.304833174 1.075574448 1.269653282 1.592348585 1.114659509 1 11.33230102 -1 0.026378745 1.00E-15 2.914450763 0.38502523 0.125700608 1369.766734 2.804846379 104.9778347 227.0023851 0.1 1 2.914450763 TDASSASSFLDSDELER ddPTM_HeLa_Curcumin_4h_R1 1 TDASSASSFLDSDELER 17 0 G3XAC6;Q14498-2;Q14498;H0Y4X3;Q14498-3;A0A0U1RQW2;A0A0U1RQH7 G3XAC6 RBM39 RNA-binding protein 39 0 0 344.47 2.80E-150 12260000 879.19 990.55 1024.8 1021.1 1245.9 1024.6 922.99 872.36 1203.1 1272 FALSE FALSE TRUE 809.6011838 1076.168728 1062.77999 1016.874959 1231.043456 812.0864104 948.8866153 1138.338548 1071.12294 1316.201905 0.615104096 0.817631948 0.807459695 0.772582804 0.935299859 0.616992277 0.720927854 0.864866206 0.813798351 1 10.3621651 -9.562891357 1.342558652 0.999770362 0.750706638 0.106974366 0.110862743 0.319503881 1.033596893 0.071674557 0.016931548 2.74E-10 9.562891357 -0.249063724 TDAY(ph)VRAMT(ph)EKR ddPTM_HeLa_Curcumin_4h_R1 1 TDAYVRAMTEKR 12 2 Q16518 Q16518 RPE65 Retinoid isomerohydrolase 2 0 TDAY(1)VRAMT(1)EKR 107.45 0.0026152 13072000 1477.3 1536.6 1558.6 1608.6 1706.2 2047.8 1650.9 1442.9 1588.4 1643.7 TRUE FALSE FALSE 1360.370146 1669.416857 1616.363087 1601.944039 1685.854679 1623.063197 1697.219811 1882.833568 1414.156494 1700.818453 0.799832659 0.981537362 0.95034428 0.941866568 0.991202016 0.954283624 0.997884171 1.107016193 0.831456462 1 10.73201344 -1.000011837 0.497649455 0.913908312 6.855432182 0.484881678 0.059410115 79.7986349 0.770812979 0.015489092 498.2014364 0.099997274 1.000011837 5.94152387 TDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPS(ph)PEAR ddPTM_HeLa_Curcumin_4h_R1 2 TDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEAR 42 0 Q15424-2;Q15424;Q15424-4;Q15424-3;Q14151 Q15424-2;Q14151 SAFB;SAFB2 Scaffold attachment factor B1;Scaffold attachment factor B2 1 0 TDCEPVGLEPAVEQSSAASELAEASSEELAEAPT(0.014)EAPS(0.986)PEAR;TDCEPVGLEPAVEQSS(0.001)AAS(0.001)ELAEAS(0.006)S(0.006)EELAEAPT(0.021)EAPS(0.963)PEAR ; 111.46 9.87E-20 27750000 12548.5 10752.4 11125.6 11054.9 12963.7 15365 12400.4 11828.4 11006.1 10213 TRUE FALSE FALSE 11555.27298 11681.78954 11537.92452 11009.15775 12809.11634 12178.1258 12748.32185 15434.82471 9798.758366 10567.90099 1.093431231 1.105403008 1.091789612 1.041754438 1.212077626 1.152369407 1.206324876 1.460538353 0.927218979 1 13.36740123 -1 0.415466219 1.043057267 7.910195571 0.809793505 0.060355852 18.40497853 0.212042791 0.012019971 105.7694845 0.1 1 6.867138304 TDCSSGDASRPSSDNADS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 TDCSSGDASRPSSDNADSPK 20 1 E9PMR6;Q9NZN5-2;Q9NZN5 E9PMR6 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 0 TDCSSGDASRPSSDNADS(1)PK;T(0.001)DCS(0.002)S(0.006)GDAS(0.005)RPS(0.015)S(0.015)DNADS(0.956)PK ; 84.025 0.00092298 42972000 8797.3 7881.8 8644.8 9225.3 9274.8 7943.7 6468.9 5364.1 9032.8 7964.8 TRUE FALSE FALSE 8100.984422 8563.067671 8965.183893 9187.128153 9164.204068 6296.087076 6650.399924 6999.589397 8041.924439 8241.576207 0.982941153 1.039008493 1.087799672 1.114729503 1.111947986 0.763942105 0.806933013 0.849302272 0.97577505 1 13.00870456 -5.253079508 24.93282692 1.019133373 0.806746507 0.791738533 0.054829209 253.3982636 755743.1281 0.009021443 0.022593043 5.58E-06 5.253079508 -0.212386867 TDDEVVQREEEAIQLDGLNASQIR ddPTM_HeLa_Curcumin_4h_R1 2 TDDEVVQREEEAIQLDGLNASQIR 24 1 P14625;Q96GW1;A0A1W2PRR1 P14625 HSP90B1 Endoplasmin 0 0 ; ; 66.845 0.0011295 20806000 2589.3 2170.87 2484.4 2493.9 2476.7 2799.5 2210.3 1923 2757.7 2292.4 FALSE FALSE TRUE 2384.354173 2358.51033 2576.47405 2483.580903 2447.16697 2218.852143 2272.315069 2509.313848 2455.187209 2372.060729 1.005182601 0.994287499 1.086175416 1.047014046 1.031662866 0.935411187 0.957949787 1.057862396 1.035043993 1 11.21192523 -4.199894424 22.19441685 1.005755673 1.057864284 0.097619957 0.041348884 39730.70549 14325439.25 0.005711643 16.44319996 6.31E-05 4.199894424 0.05210861 TDEAAFQK ddPTM_HeLa_Curcumin_4h_R1 2 TDEAAFQK 8 0 P26447 P26447 S100A4 Protein S100-A4 0 0 ; ; 122.18 0.00249 16644400 6953 5629.3 6973.9 6534.7 7541.4 7546.9 6765.2 6448.9 7977.7 6955.1 FALSE FALSE TRUE 6402.662713 6115.871608 7232.358869 6507.661143 7451.47373 5981.587869 6955.013304 8415.139923 7102.566269 7196.789207 0.889655446 0.849805577 1.004942435 0.904245068 1.035388632 0.831146737 0.966405032 1.169290871 0.986907642 1 12.81313769 -4.27520994 4.568554507 0.939609759 1.18154694 0.524695024 0.065597179 0.108565145 5.78551736 0.009085944 0.081835269 5.31E-05 4.27520994 0.241937181 TDEDAVLMDGMTESDT(ph)ASVNENGLGKR ddPTM_HeLa_Curcumin_4h_R1 1 TDEDAVLMDGMTESDTASVNENGLGKR 27 1 E7EU85;E9PFF5;P51114-2 E7EU85 FXR1 Fragile X mental retardation syndrome-related protein 1 1 0 TDEDAVLMDGMT(0.31)ES(0.31)DT(0.345)AS(0.036)VNENGLGKR 52.321 0.0030921 10112000 1753.7 1118.2 1381.1 1385.9 1339.3 1895 1370.7 1246.9 1899.6 1674.9 TRUE FALSE FALSE 1614.892795 1214.852225 1432.284781 1380.165513 1323.329722 1501.955639 1409.158153 1627.07407 1691.218633 1733.10265 0.931792929 0.700969573 0.826428129 0.796355318 0.763561075 0.866628205 0.813084068 0.938821523 0.975832927 1 10.75914139 -7.460269063 6.207969382 0.970474933 0.814350903 0.593363033 0.059266625 0.113764162 8.467076512 0.010328727 0.011647952 3.47E-08 7.460269063 -0.15612403 TDEERPPVEHS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 2 TDEERPPVEHSPEK 14 1 Q15170-2 Q15170-2 1 0 TDEERPPVEHS(1)PEK;TDEERPPVEHS(1)PEK ; 81.346 0.0078126 69152000 8208.6 7240.8 8012.8 6976.2 9606.1 8386.8 7515.3 6923.1 7061.1 6558.2 TRUE FALSE FALSE 7558.880648 7866.662488 8309.761417 6947.334333 9491.553531 6647.283141 7726.159092 9033.92132 6286.514996 6786.096962 1.11387749 1.159232256 1.224527363 1.023759957 1.39867638 0.97954438 1.13852766 1.331239646 0.926381546 1 12.72836633 -8.599522071 0.326647869 0.955134963 1.197320293 0.328090409 0.120216767 2.255366948 0.470908144 0.211210959 0.066866211 2.51E-09 8.599522071 0.24218533 TDEGIAYR ddPTM_HeLa_Curcumin_4h_R1 2 TDEGIAYR 8 0 P32119 P32119 PRDX2 Peroxiredoxin-2 0 0 ; ; 120.49 0.0026728 20206700 6867.8 6078.2 5905.9 6398.3 5808.2 8444 6317.9 5702.4 6829.6 6036 FALSE FALSE TRUE 6324.206383 6603.572524 6124.777849 6371.82553 5738.941008 6692.619217 6495.16327 7441.035509 6080.409967 6245.750551 1.012561474 1.057290468 0.980631199 1.020185721 0.918855302 1.071547633 1.039933186 1.191375712 0.973527508 1 12.60865924 -3.890831325 1.320138268 1.005294927 1.449092606 0.670083203 0.03970132 1.274103812 0.996194672 0.005128985 0.96160651 0.000128579 3.890831325 0.443797679 TDENIDTPGT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 TDENIDTPGTPK 12 0 Q6ULP2-7;Q6ULP2-8;Q6ULP2-6;Q6ULP2;Q6ULP2-9;B8ZZI9;A0A0U1RR74 Q6ULP2-7 AFTPH Aftiphilin 1 0 TDENIDT(0.002)PGT(0.998)PK 137.81 0.0040311 0 2180.5 2066.5 1809.8 2118.5 1972.9 2823.3 2632.4 1922.4 2370 1796.5 TRUE FALSE FALSE 2007.911124 2245.119052 1876.87278 2109.734208 1949.374456 2237.715755 2706.258059 2508.53091 2110.016929 1858.928241 1.080144505 1.207749176 1.009653164 1.13491966 1.048655033 1.203766614 1.455816313 1.349450105 1.135071749 1 10.86025536 -4.978657052 3.064294471 1.057961713 1.402768605 0.754188489 0.069368574 0.077810598 1.489044669 0.009860894 0.033137505 1.05E-05 4.978657052 0.344806892 TDESSPVLS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 TDESSPVLSPR 11 0 Q8NA72-3;Q8NA72 Q8NA72-3 POC5 Centrosomal protein POC5 1 0 TDESSPVLS(1)PR;TDESSPVLS(1)PR ; 148.13 0.0007746 44120000 3841.6 3695.6 3741.5 3501.1 3676.1 3508.4 2866.3 2405.9 4029.8 3655.2 TRUE FALSE FALSE 3537.533306 4015.031197 3880.163281 3486.613376 3632.264908 2780.718292 2946.720664 3139.447835 3587.741022 3782.217928 0.935306578 1.061554694 1.025896274 0.921843596 0.960353152 0.735208374 0.779098592 0.830054718 0.948581253 1 11.88501678 -5.306354305 7.034886802 0.976293159 0.78134024 0.80041311 0.045213716 0.078903015 10.44459028 0.006907559 0.015663573 4.94E-06 5.306354305 -0.194952919 TDEVPAGGS(ph)RS(ph)EAEDEDDEDYVPYVPLR ddPTM_HeLa_Curcumin_4h_R1 1 TDEVPAGGSRSEAEDEDDEDYVPYVPLR 28 1 D6RD33;D6RGI7;A0A499FJW5;Q9UJV9 D6RD33 DDX41 Probable ATP-dependent RNA helicase DDX41 2 0 T(0.004)DEVPAGGS(0.998)RS(0.998)EAEDEDDEDYVPYVPLR 75.896 6.72E-05 7400800 1007.8 698.26 646.98 553.9 845.62 778.11 769.95 581.67 662.95 630.94 TRUE FALSE FALSE 928.0315666 758.614483 670.9576479 551.6081086 835.5365338 616.7212149 791.5527248 759.0185053 590.2260436 652.865118 1.421475188 1.161977355 1.027712508 0.844903631 1.279799626 0.944638024 1.212429188 1.1625962 0.904055106 1 9.350641151 -6.963859622 9.053296161 1.203861108 1.078452915 0 0.17871771 0.604288563 141.2684221 0.030929595 0.040607834 1.09E-07 6.963859622 -0.125408193 TDEVPAGGS(ph)RSEAEDEDDEDYVPYVPLR ddPTM_HeLa_Curcumin_4h_R1 1 TDEVPAGGSRSEAEDEDDEDYVPYVPLR 28 1 D6RD33;D6RGI7;A0A499FJW5;Q9UJV9 D6RD33 DDX41 Probable ATP-dependent RNA helicase DDX41 1 0 T(0.003)DEVPAGGS(0.499)RS(0.499)EAEDEDDEDYVPYVPLR 93.34 1.12E-07 50417000 5329.1 3579.7 3943.2 4935.3 4951.5 5913.1 4498.6 4195.2 5616.7 3908.6 TRUE FALSE FALSE 4907.296112 3889.113317 4089.338461 4914.879036 4892.456596 4686.656406 4624.818609 5474.297168 5000.562062 4044.423559 1.213348711 0.961598918 1.01110539 1.21522362 1.209679581 1.158794656 1.143505012 1.353542004 1.236409092 1 11.98171838 -1.001895355 0.019089552 9.00E-09 2.615970885 0.094398261 0.111843941 3082.398861 4.584121647 237.0591752 414.5452831 0.099564529 1.001895355 2.615970876 TDEVPAGGSRS(ph)EAEDEDDEDYVPYVPLR ddPTM_HeLa_Curcumin_4h_R1 1 TDEVPAGGSRSEAEDEDDEDYVPYVPLR 28 1 D6RD33;D6RGI7;A0A499FJW5;Q9UJV9 D6RD33 DDX41 Probable ATP-dependent RNA helicase DDX41 1 0 T(0.002)DEVPAGGS(0.174)RS(0.823)EAEDEDDEDYVPYVPLR 115.77 4.95E-11 54795000 1156.1 1024 776.44 842.02 983.68 1284.2 947.24 860.51 1014.6 880.2 TRUE FALSE FALSE 1064.593465 1112.509997 805.2155494 838.5359443 971.9502585 1017.842444 973.817005 1122.875538 903.3009184 910.7868845 1.168872195 1.221482233 0.884087774 0.920671958 1.06715443 1.117541833 1.069204027 1.232863095 0.991780771 1 9.830969706 -3.513852968 1.479536181 1.066501683 2.109709279 0.211401482 0.100988654 13.69839336 5.227712798 0.016155198 36.0538217 0.0003063 3.513852968 1.043207596 TDGALLVNAMFFKPHWDEK ddPTM_HeLa_Curcumin_4h_R1 1 TDGALLVNAMFFKPHWDEK 19 1 P50454;E9PR70;E9PPV6;E9PK86;E9PMI5 P50454 SERPINH1 Serpin H1 0 0 136.39 9.11E-05 9623400 3910.3 3186.5 3551.6 3355.4 2984 5391.2 2916.7 1792.2 3415.4 3287.7 FALSE FALSE TRUE 3600.795629 3461.926861 3683.22542 3341.516244 2948.417749 4273.004349 2998.534752 2338.63353 3040.739165 3401.94733 1.058451316 1.01763094 1.082681495 0.982236325 0.866685302 1.256046591 0.881417159 0.687439664 0.893823116 1 11.73214509 -4.52327446 24.99984989 1.030252825 0.735933953 0.496434546 0.102774496 5.45889445 344921.8519 0.011736252 0.04480064 3.00E-05 4.52327446 -0.294318872 DSLGDFIEHYAQLGPSS(ph)PEQLAAGAEEGGGPR ddPTM_HeLa_Curcumin_4h_R1 1 DSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPR 32 0 Q96QR8 Q96QR8 PURB Transcriptional activator protein Pur-beta 1 0 DSLGDFIEHYAQLGPS(0.347)S(0.653)PEQLAAGAEEGGGPR 107.68 1.62E-11 25790000 1507.6 995.78 1084.7 1162.5 1195 1915.4 1255.6 1688.2 1392.2 1060.9 TRUE FALSE FALSE 1388.271869 1081.850786 1124.899936 1157.689883 1180.750405 1518.124449 1290.828757 2202.924408 1239.479143 1097.766196 1.264633466 0.985502004 1.024717231 1.05458693 1.075593701 1.382921477 1.175868561 2.006733689 1.129092103 1 10.1003551 -1.848730738 1.091273106 1.106712669 200 0.840166264 0.116313371 114.8931688 0.785542379 0.019861476 56431.89355 0.014166718 1.848730738 198.8932873 up TDGS(ph)IS(ph)GDRQPVTVADYISR ddPTM_HeLa_Curcumin_4h_R1 1 TDGSISGDRQPVTVADYISR 20 1 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 2 0 T(0.107)DGS(0.925)IS(0.961)GDRQPVT(0.007)VADY(0.001)ISR 67.478 0.0055175 85573000 3202.9 2949.7 2213.4 3452.2 3184.6 3302.2 2877.3 2846 3305.5 3182.1 TRUE FALSE FALSE 2949.387085 3204.658924 2295.430551 3437.915711 3146.625725 2617.286497 2958.029294 3713.732299 2942.89492 3292.677738 0.895741193 0.973268318 0.697131859 1.04410938 0.955643393 0.794880855 0.898365868 1.127876031 0.893769495 1 11.6850456 -9.34060714 1.020260159 1.000851863 0.91609673 0 0.118293502 1.24579485 2.283278469 0.077398276 0.019485768 4.56E-10 9.34060714 -0.084755133 TDGS(ph)ISGDRQPVTVADYISR ddPTM_HeLa_Curcumin_4h_R1 1 TDGSISGDRQPVTVADYISR 20 1 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 0 TDGS(0.911)IS(0.089)GDRQPVTVADYISR 177.44 1.85E-06 77452000 2976.5 2534.2 3280.9 3318.7 2982.8 3725.8 2461.5 2323.7 3295.4 3247.6 TRUE FALSE FALSE 2740.906884 2753.244956 3402.49304 3304.968099 2947.232058 2953.027082 2530.563065 3032.185433 2933.902865 3360.453858 0.815635923 0.819307472 1.012509971 0.983488611 0.877033931 0.878758408 0.753042051 0.902314259 0.873067445 1 11.71444038 -9.510800485 1.269675538 0.999816313 0.874168878 0 0.082242319 0.504742822 1.459954638 0.054481797 0.013229014 3.08E-10 9.510800485 -0.125647434 TDGS(ph)QKTESSTEGKEQEEK ddPTM_HeLa_Curcumin_4h_R1 1 TDGSQKTESSTEGKEQEEK 19 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 0 T(0.108)DGS(0.44)QKT(0.44)ES(0.008)S(0.003)T(0.001)EGKEQEEK 62.589 0.013382 12684000 3197.2 2338.9 2570.4 3187.9 3024.9 3401.2 3558.1 2743.8 3119.7 3503.6 TRUE FALSE FALSE 2944.138246 2541.064094 2665.661285 3174.709314 2988.830043 2695.752781 3657.93071 3580.371989 2777.476715 3625.349839 0.812097695 0.700915555 0.735283877 0.875697369 0.824425276 0.743584178 1.008986959 0.987593515 0.766126536 1 11.8239045 -3.081492742 14.53348711 0.877126748 44.13323795 0 0.115334545 0 0 0.016903683 0 0.00082891 3.081492742 43.25611121 TDGSIS(ph)GDRQPVTVADYISR ddPTM_HeLa_Curcumin_4h_R1 2 TDGSISGDRQPVTVADYISR 20 1 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 0 T(0.001)DGS(0.191)IS(0.804)GDRQPVT(0.003)VADYISR;TDGS(0.009)IS(0.982)GDRQPVT(0.009)VADYISR ; 193.27 2.23E-09 34409400 3220.2 2939.9 2812.6 3127.7 2872 3868 2444.3 2358.8 3442 2445.8 TRUE FALSE FALSE 2965.317772 3194.011856 2916.83743 3114.758406 2837.753276 3065.733199 2512.88048 3077.987261 3064.421211 2530.791368 1.171695861 1.262060515 1.152539663 1.230744836 1.121290878 1.211373343 0.992922811 1.216215331 1.210854933 1 11.30537286 -9.067643111 0.890809908 1.001890842 1.167062864 0 0.095485903 0.41171145 0.602345288 0.042587188 0.013375614 8.56E-10 9.067643111 0.165172022 TDGSQK(ac)TESSTEGKEQEEK ddPTM_HeLa_Curcumin_4h_R1 1 TDGSQKTESSTEGKEQEEK 19 2 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 0 1 TDGSQK(1)TESSTEGKEQEEK 235.79 3.70E-38 1997900 763.82 802.32 681.99 676.39 755.21 1245.6 682.6 821 939.63 800.68 FALSE TRUE FALSE 703.362841 871.6689657 707.2651493 673.5912774 746.204614 987.2485192 701.7519189 1071.319121 836.5549398 828.5035704 0.848955715 1.052100434 0.853665783 0.813021575 0.900665538 1.191604423 0.847011339 1.293077253 1.009717966 1 9.694364104 -5.282476711 24.66881898 0.920352892 1.084209045 0.297525571 0.128281714 643.0513408 754054.85 0.017157185 0.038403216 5.22E-06 5.282476711 0.163856153 TDIFGVEETAIGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 TDIFGVEETAIGKK 14 1 Q15459;Q15459-2 Q15459 SF3A1 Splicing factor 3A subunit 1 0 1 TDIFGVEETAIGK(1)K 213.38 1.21E-20 721690 287.21 212.58 185.18 119.36 201.72 263.41 310.42 320.38 474.03 135.6 FALSE TRUE FALSE 264.4770254 230.954468 192.0429337 118.8661199 199.3146207 208.7757968 319.1295497 418.0623872 422.030095 140.3120899 1.884919722 1.646005473 1.368684151 0.847155224 1.420509244 1.487938758 2.274426601 2.979517926 3.007795659 1 7.132495513 -4.537396745 2.074322961 1.395585563 3.053221245 0.336958704 0.580405742 0.199252008 1.366552775 0.054127532 0.498081698 2.90E-05 4.537396745 1.657635681 TDK(ac)TLVLLMGK ddPTM_HeLa_Curcumin_4h_R1 2 TDKTLVLLMGK 11 1 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 1 ; TDK(1)TLVLLMGK;TDK(1)TLVLLMGK 110.86 4.01E-05 0 180.57 157.23 387.2 311.63 308.843 329.14 392.55 223.6 304.07 136.619 FALSE TRUE FALSE 166.277694 170.8202606 401.5499726 310.3405576 305.1602489 260.8726538 403.5638965 291.7746107 270.7142817 141.3665001 1.176217094 1.208350355 2.840488888 2.195290663 2.158646134 1.845364027 2.854735006 2.06395865 1.914981849 1 7.143296472 -6.839573841 7.313076579 1.090704405 2.313352212 0.579240732 0.399113216 0.069569016 5.517438412 0.046492304 0.061298031 1.45E-07 6.839573841 1.222647806 TDKSSAS(ph)APDVDDPEAFPALA ddPTM_HeLa_Curcumin_4h_R1 1 TDKSSASAPDVDDPEAFPALA 21 1 Q8NC51-2;Q8NC51;Q8NC51-4;Q8NC51-3 Q8NC51-2 SERBP1 Plasminogen activator inhibitor 1 RNA-binding protein 1 0 T(0.083)DKS(0.276)S(0.276)AS(0.366)APDVDDPEAFPALA 65.207 0.0023135 12979000 2024.1 2180.5 2175.3 1924.8 1903.8 2395.9 1829.8 3943.9 2356.3 2192.9 TRUE FALSE FALSE 1863.890349 2368.972704 2255.918532 1916.835688 1881.098428 1898.963333 1881.139263 5146.376955 2097.819785 2269.103112 0.821421618 1.044012805 0.994189519 0.844754775 0.829005266 0.836878378 0.829023262 2.268022519 0.924514966 1 11.14790645 -4.259424731 24.99745963 0.907800355 2.268022982 0.963430373 0.079798234 26.9317132 334139.8386 0.012955346 0.113500192 5.50E-05 4.259424731 1.360222627 TDKTLVLLMGK ddPTM_HeLa_Curcumin_4h_R1 1 TDKTLVLLMGK 11 1 P07737;K7EJ44 P07737 PFN1 Profilin-1 0 0 102.53 0.00019323 0 1014.1 592.34 737.53 492.31 741.56 1285.2 750.83 1040.6 913.85 939.32 FALSE FALSE TRUE 933.8329149 643.5392302 764.8635106 490.2729517 732.7173813 1018.635033 771.896269 1357.87415 813.6029413 971.9613001 0.960771704 0.662103759 0.786927947 0.504416124 0.753854481 1.048020155 0.794163583 1.397045489 0.837073391 1 9.924755062 -7.488636156 22.251352 0.982693716 0.833923254 0.010701726 0.230812956 229.031276 148831.1734 0.038468852 0.042605029 3.25E-08 7.488636156 -0.148770461 TDLEKDIISDTSGDFR ddPTM_HeLa_Curcumin_4h_R1 3 TDLEKDIISDTSGDFR 16 1 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YNP5;H0YN28;H0YKS4;H0YL33;H0YNA0;H0YN52;P07355-2 P07355;P07355-2 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 0 ;; ;; 118.52 0.00088857 155002000 22354.5 17425.3 18831.9 21326.4 22388.1 30632.5 24457.2 25411.2 25819 17615 FALSE FALSE TRUE 20585.11774 18931.46529 19529.82678 21238.15701 22121.13653 24278.9742 25143.40321 33158.9579 22986.7203 18227.11994 1.129367547 1.038642712 1.0714708 1.165195438 1.213638611 1.332024713 1.379450143 1.819209947 1.261127395 1 14.153799 -1 0.468315045 1.052840307 20.18307267 0.873610849 0.080200362 12.40338183 0.12861337 0.011341796 231.2003021 0.1 1 19.13023237 TDLEKDIISDTSGDFRK ddPTM_HeLa_Curcumin_4h_R1 2 TDLEKDIISDTSGDFRK 17 2 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YNP5;H0YN28;H0YKS4;H0YL33;H0YNA0;H0YN52;P07355-2 P07355;P07355-2 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 0 ; ; 95.751 0.0061328 315389000 4983.7 3828.1 3977.79 4738.8 4357 6351.1 5254.95 5784.7 6096.7 4014.5 FALSE FALSE TRUE 4589.234886 4158.983906 4125.210397 4719.192101 4305.045621 5033.810268 5402.389754 7548.428401 5427.907263 4154.003576 1.104773937 1.001198923 0.993068571 1.136058748 1.036360596 1.211797288 1.300526024 1.817145378 1.306668895 1 12.02028674 -2.079214566 0.789182906 1.043858097 27.32522512 0.836009604 0.096164722 9.776604137 0.221720915 0.00853939 429.7740812 0.008332694 2.079214566 26.28136702 TDLETS(ph)PGAAPR ddPTM_HeLa_Curcumin_4h_R1 2 TDLETSPGAAPR 12 0 Q6F5E8-2;Q6F5E8 Q6F5E8-2 RLTPR Leucine-rich repeat-containing protein 16C 1 0 TDLET(0.14)S(0.86)PGAAPR;TDLET(0.133)S(0.867)PGAAPR ; 150.09 0.00054767 44376000 7726.1 6483.5 6590.3 7361 6807.1 10661.1 7187.9 4331.6 8888.9 6500.3 TRUE FALSE FALSE 7114.571032 7043.90485 6834.542315 7330.542132 6725.929778 8449.867685 7389.573129 5652.2849 7913.809909 6726.184941 1.057742404 1.047236273 1.016109782 1.089851409 0.999962064 1.256264548 1.098627706 0.840340393 1.176567397 1 12.71557273 -9.302770177 0.4938401 0.986104514 1.060499111 0 0.112057585 4.775306377 1.543114176 0.175092642 0.025746985 4.98E-10 9.302770177 0.074394596 TDLLLEPYNK ddPTM_HeLa_Curcumin_4h_R1 2 TDLLLEPYNK 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ; ; 185.81 3.97E-16 4022700 7122.9 5745.8 6560.1 6347.3 7295.3 7935.1 6804.5 6056.2 6392.8 6147.4 FALSE FALSE TRUE 6559.114949 6242.441349 6803.223077 6321.036554 7208.308312 6289.270813 6995.415957 7902.707501 5691.525834 6361.021692 1.031141736 0.981358287 1.069517352 0.993714038 1.133199769 0.988720227 1.099731505 1.242364495 0.894750263 1 12.63504279 -1.000000062 0.799656093 1.018062849 57.30194213 0.588171446 0.05914607 184.0791948 0.604106307 0.006478442 18781.23313 0.099999986 1.000000062 56.28387928 TDLQGSAS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 TDLQGSASPSK 11 0 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 0 T(0.001)DLQGSAS(0.997)PS(0.002)K 186.16 7.69E-05 17500000 5139 4756.3 5401.5 5501.6 6319.8 4774.5 4155.7 2548.9 4487.2 4238.2 TRUE FALSE FALSE 4732.242727 5167.413378 5601.684342 5478.835837 6244.440513 3784.21488 4272.297758 3326.047876 3994.965386 4385.477135 1.079071349 1.178301293 1.277326086 1.249313511 1.423890793 0.862896958 0.974192232 0.758423263 0.910953418 1 12.0985181 TDLQGSAS(ph)PSKVEGVHTPR ddPTM_HeLa_Curcumin_4h_R1 1 TDLQGSASPSKVEGVHTPR 19 1 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 0 T(0.014)DLQGS(0.28)AS(0.528)PS(0.175)KVEGVHT(0.002)PR 61.256 0.0090436 64913000 1129.2 784.91 1008.4 1027 1449 1343.2 816.33 898.38 1360.5 1158.9 TRUE FALSE FALSE 1039.822628 852.7541229 1045.772191 1022.750546 1431.721621 1064.605179 839.2340228 1172.291926 1211.256554 1199.171689 0.867117393 0.711119293 0.872078786 0.852880831 1.193925469 0.887783784 0.69984476 0.977584726 1.010077677 1 10.22782251 -9.155056433 1.065059298 0.995659768 0.881152872 0.120034069 0.130648127 0.927583784 1.988055034 0.072551429 0.024164153 7.00E-10 9.155056433 -0.114506896 TDLQGSASPS(ph)KVEGVHTPR ddPTM_HeLa_Curcumin_4h_R1 3 TDLQGSASPSKVEGVHTPR 19 1 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 0 T(0.001)DLQGS(0.041)AS(0.11)PS(0.818)KVEGVHT(0.03)PR;TDLQGSAS(0.001)PS(0.499)KVEGVHT(0.499)PR;T(0.003)DLQGS(0.044)AS(0.082)PS(0.676)KVEGVHT(0.195)PR ;; 68.845 0.0041748 54635000 12410.5 8547.5 8154 8928.1 11245.5 13277.7 7858.7 4471.42 13310.6 9527.5 TRUE FALSE FALSE 11428.19583 9286.307813 8456.194413 8891.157888 11111.40476 10523.75535 8079.193971 5834.735374 11850.46048 9858.579916 1.159213186 0.941951873 0.857749745 0.901870043 1.127079646 1.067471729 0.819508899 0.591843392 1.202045384 1 13.26716413 -4.494725164 2.59759058 1.042661579 0.586067361 0.627529036 0.107160446 0.165129176 1.899431429 0.015982713 0.12937209 3.20E-05 4.494725164 -0.456594218 TDNSSLS(ph)SPLNPK ddPTM_HeLa_Curcumin_4h_R1 2 TDNSSLSSPLNPK 13 0 Q9UIG0-2;Q9UIG0 Q9UIG0-2 BAZ1B Tyrosine-protein kinase BAZ1B 1 0 T(0.001)DNS(0.004)S(0.013)LS(0.491)S(0.491)PLNPK;TDNSS(0.003)LS(0.639)S(0.358)PLNPK ; 179.93 0.00015443 86027000 12796.7 8762.5 10843.2 12100.3 12059.2 22297 18091.2 5260.4 13766.8 9520.2 TRUE FALSE FALSE 11783.82769 9519.891455 11245.05853 12050.23216 11915.40192 17672.35086 18598.79038 6864.271744 12256.61648 9851.026241 1.196203056 0.966385757 1.141511377 1.223246378 1.209559453 1.793960388 1.888005364 0.696807782 1.244196917 1 13.26605831 -5.464910603 6.479204615 1.100794148 1.504992854 0.17889157 0.309551846 0.230547781 20.48801205 0.041066128 0.091800762 3.43E-06 5.464910603 0.404198706 TDNVSDFSES(ph)SDSENSNKR ddPTM_HeLa_Curcumin_4h_R1 1 TDNVSDFSESSDSENSNKR 19 1 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 0 TDNVSDFS(0.008)ES(0.609)S(0.382)DS(0.001)ENSNKR 95.742 0.00065119 10154000 1067.9 962.23 1066.2 1034.7 893.49 907.57 713.6 864.99 1277 1107.6 TRUE FALSE FALSE 983.3745882 1045.400874 1105.71431 1030.418686 882.8357153 719.3297516 733.6216954 1128.721469 1136.916295 1146.089018 0.85802636 0.912146315 0.964771752 0.899073868 0.770302919 0.627638639 0.640108826 0.984846248 0.991996501 1 10.16250339 -5.760095546 3.624842638 0.931406163 0.734272683 0.446066478 0.099293976 0.1589996 4.466601981 0.014925951 0.029767315 1.74E-06 5.760095546 -0.19713348 K(ac)LGEMR ddPTM_HeLa_Curcumin_4h_R1 1 KLGEMR 6 1 I3L2G3;I3L139;Q9HA64 I3L2G3 FN3KRP Ketosamine-3-kinase 0 1 K(1)LGEMR 86.086 0.014418 0 7527.6 5707.1 6755 6139.4 7351.1 8052.4 5203.7 1795.9 6399.3 6588.4 FALSE TRUE FALSE 6931.782517 6200.396294 7005.346242 6113.99679 7263.442934 6382.241471 5349.701817 2343.461643 5697.3128 6817.34641 1.016786019 0.909502895 1.027576688 0.896829415 1.065435508 0.936176789 0.784719082 0.343749826 0.835708274 1 12.73499458 -4.194441527 1.567608455 0.997390953 0.019588808 0.869566198 0.071520089 0.188665141 0.378395114 0.006676351 0.295504667 6.39E-05 4.194441527 -0.977802144 down TDPECTAPIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 TDPECTAPIKK 11 1 Q5T7F5;Q8N1G2 Q5T7F5 CMTR1 Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 0 1 ; TDPECTAPIK(1)K;TDPECTAPIK(1)K 121.6 1.02E-07 5097000 4102.7 4275.1 4273.6 4467.3 3437.5 4899.4 2812.6 2562.7 4092.9 4152.1 FALSE TRUE FALSE 3777.966966 4644.620595 4431.983375 4448.815496 3396.510058 3883.209212 2891.513986 3344.055433 3643.91911 4296.385166 0.879336191 1.081053121 1.031560999 1.03547874 0.790550643 0.903831724 0.673010886 0.77834163 0.848136042 1 12.06890762 -5.228652065 1.455438944 0.964008088 0.734411338 0.51061866 0.088441717 0.271793142 1.057601379 0.01317831 0.052611022 5.91E-06 5.228652065 -0.229596749 TDPTTLTDEEINR ddPTM_HeLa_Curcumin_4h_R1 1 TDPTTLTDEEINR 13 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586;A0A494C1T2 V9GZ78 MTHFD1 "C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed" 0 0 166.69 9.53E-06 2186300 300.37 216.55 245.24 223.54 127.29 289.86 321.01 250.24 312.95 201.06 FALSE FALSE TRUE 276.5953976 235.2676171 254.3288101 222.6150507 125.7721499 229.7397686 330.0166766 326.537024 278.620168 208.04682 1.329486303 1.130839765 1.222459493 1.070023808 0.604537718 1.104269551 1.586261576 1.569536242 1.339218585 1 7.700764427 -4.761375777 24.99971288 1.11348222 1.577899069 0.486638082 0.195910212 1.110804013 435508.2761 0.029460936 0.097785395 1.73E-05 4.761375777 0.464416849 TDPVPEEGEDVAATISATETLSEEEQEELRR ddPTM_HeLa_Curcumin_4h_R1 1 TDPVPEEGEDVAATISATETLSEEEQEELRR 31 1 H0YC42;P55327-2;P55327;P55327-3;P55327-4;P55327-7;P55327-5;P55327-6;E5RFR7;H0YC44;P55327-8 H0YC42 TPD52 Tumor protein D52 0 0 103.74 2.51E-10 4627800 783.03 508.3 585.92 526.17 691.33 838.54 590.73 441.35 524.29 639.06 FALSE FALSE TRUE 721.0523493 552.2351871 607.6347106 523.992848 683.0863413 664.6173517 607.3042939 575.9155833 466.7766987 661.2672874 1.090409828 0.835116446 0.918894254 0.792407031 1.032995816 1.005066127 0.918394582 0.870927073 0.705882035 1 9.369089724 -7.270373682 24.99638835 1.042693531 0.914967761 0 0.127653445 488.1638637 1365782.113 0.012823204 0.014778628 5.37E-08 7.270373682 -0.12772577 TDPVTGR ddPTM_HeLa_Curcumin_4h_R1 2 TDPVTGR 7 0 O14979-3;O14979-2;A0A087WUK2;O14979 O14979-3 HNRNPDL Heterogeneous nuclear ribonucleoprotein D-like 0 0 ; ; 107.32 0.015659 5332500 350.37 602.47 322.37 431.18 376.57 406.89 391.4 259.59 439.96 429.93 FALSE FALSE TRUE 322.6378448 654.5448222 334.3173158 429.3958914 372.0796487 322.4964274 402.3816306 338.737796 391.6974887 444.8700355 0.725240675 1.471316947 0.751494345 0.965216484 0.836378311 0.72492279 0.904492545 0.76143091 0.880476223 1 8.797240118 -5.582300688 6.810713409 0.913140114 0.803299128 0.100625327 0.200618726 0.524225444 47.6360826 0.030135891 0.060742076 2.62E-06 5.582300688 -0.109840986 TDQAQK(ac)AEGAGDAK ddPTM_HeLa_Curcumin_4h_R1 1 TDQAQKAEGAGDAK 14 1 P05204 P05204 HMGN2 Non-histone chromosomal protein HMG-17 0 1 TDQAQK(1)AEGAGDAK 210.91 2.05E-19 3020800 1030.5 884.57 978.84 871.23 1078.4 1366.1 1287.1 786.43 1369.7 996.66 FALSE TRUE FALSE 948.9348376 961.0282892 1015.116671 867.6250811 1065.540784 1082.755461 1323.212562 1026.208887 1219.447337 1031.293861 0.920140101 0.931866586 0.984313696 0.84129763 1.033207726 1.049900035 1.283060641 0.995069326 1.182444096 1 10.01023976 -5.242937219 2.563299557 0.953603332 1.13893091 0.208112553 0.108470989 0.172891145 2.222383981 0.010880162 0.03119695 5.72E-06 5.242937219 0.185327578 TDQAQKAEGAGDAK ddPTM_HeLa_Curcumin_4h_R1 2 TDQAQKAEGAGDAK 14 1 P05204 P05204 HMGN2 Non-histone chromosomal protein HMG-17 0 0 ; ; 106.55 0.0011803 6517400 5172.9 4662.6 3934.7 5450.7 3273.3 6341.1 4000.7 4006 8003.6 6599.7 FALSE FALSE TRUE 4763.459507 5065.614368 4080.523443 5428.146448 3234.268035 5025.884381 4112.948875 5227.410959 7125.625104 6829.039084 0.697529982 0.741775571 0.597525273 0.794862408 0.473605144 0.735957771 0.602273442 0.76546801 1.043430125 1 12.73746688 -9.138808227 0.488637292 1.064951856 0.656349848 0.693554745 0.091818473 0.643326727 0.223664098 0.126518573 0.022731838 7.26E-10 9.138808227 -0.408602007 GSDCSS(ph)LSESESTK ddPTM_HeLa_Curcumin_4h_R1 1 GSDCSSLSESESTK 14 0 A0A0U1RR27;Q7Z401;Q7Z401-2;H3BTW5 A0A0U1RR27 DENND4A C-myc promoter-binding protein 1 0 GSDCS(0.017)S(0.981)LS(0.001)ESESTK 187.11 2.80E-05 3554000 1655.9 1073.9 1314.4 1091.4 1316.6 1317.5 1005.8 397.82 1373.6 1254.1 TRUE FALSE FALSE 1524.833768 1166.723131 1363.11282 1086.884076 1300.900405 1044.235649 1034.020041 519.1134867 1222.919517 1297.679882 1.175046165 0.899083932 1.05042302 0.837559472 1.002481755 0.804694334 0.796822125 0.400032006 0.942389209 1 10.34171882 -4.087602172 0.577823932 1.06747172 9.91E-14 0.724799259 0.104041602 1.490821696 0.293481033 0.019521713 1.109242812 8.17E-05 4.087602172 -1.06747172 down TDRDK(ac)YNR ddPTM_HeLa_Curcumin_4h_R1 2 TDRDKYNR 8 2 D6RAH7;H9KV45;A0A087WY85;P61077;P61077-2;P61077-3 D6RAH7 UBE2D3 Ubiquitin-conjugating enzyme E2 D3 0 1 ; TDRDK(1)YNR;TDRDK(1)YNR 90.37 0.0052511 694700 206.479 0 147.23 70.8 136.09 307.76 0 267.38 66.571 0 FALSE TRUE FALSE 190.1359693 0 152.6864733 70.50704836 134.4672156 243.9271068 0 348.9029311 59.26832785 0 0 TDRGGDSIGET(ph)PTPGASK ddPTM_HeLa_Curcumin_4h_R1 1 TDRGGDSIGETPTPGASK 18 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 TDRGGDSIGET(0.768)PT(0.232)PGASK 69.27 0.012259 6468700 2384.6 2183 2386.2 2705.3 1803.3 3030.5 2024.4 1558.5 3025.4 2542.5 TRUE FALSE FALSE 2195.856394 2371.688793 2474.634671 2694.106185 1781.796825 2401.940139 2081.199216 2033.679476 2693.521189 2630.851686 0.834656095 0.901490877 0.940621125 1.024043354 0.677269964 0.912989566 0.791074323 0.77301183 1.023820994 1 11.3613142 -13.52287875 0.100898448 1.449574675 0.747688491 0.364480296 0.088393092 119.3561673 0.897614038 11.63350957 0.754882549 3.00E-14 13.52287875 -0.701886184 DS(ph)GLESPAAAEAPLR ddPTM_HeLa_Curcumin_4h_R1 1 DSGLESPAAAEAPLR 15 0 H0YM15;J3KNL7;Q8NBR6-2;Q8NBR6 H0YM15 FAM63B Protein FAM63B 1 0 DS(0.725)GLES(0.275)PAAAEAPLR 102.63 0.0030601 4042000 1536.6 1571.4 1563.3 1513.8 1867.2 2317.7 1683.4 2670.5 1638.7 1383.5 TRUE FALSE FALSE 1414.976489 1707.224814 1621.237273 1507.536297 1844.93486 1836.982894 1730.631673 3484.723157 1458.93871 1431.576522 0.988404369 1.192548765 1.132483837 1.053060227 1.288743446 1.283188754 1.208899173 2.434185741 1.019113325 1 10.48338907 -1.843377924 1.002239944 1.040709001 200 0.909657363 0.121933573 49.39563532 0.43398761 0.019472631 22121.88329 0.014342408 1.843377924 198.959291 up TDS(ph)CSSAQAQYDTPK ddPTM_HeLa_Curcumin_4h_R1 1 TDSCSSAQAQYDTPK 15 0 Q96PD2;Q96PD2-2 Q96PD2 DCBLD2 "Discoidin, CUB and LCCL domain-containing protein 2" 1 0 T(0.019)DS(0.9)CS(0.072)S(0.009)AQAQYDTPK 124.29 0.0010008 6020200 1666.9 1356.3 1212.9 2348.6 1554.6 2237.7 1393.5 889 2488.3 1886.3 TRUE FALSE FALSE 1534.963106 1473.532528 1257.851141 2338.882115 1536.06241 1773.575796 1432.59786 1160.052008 2215.339715 1951.848785 0.786414971 0.75494195 0.644440876 1.198290633 0.786978183 0.908664549 0.733969696 0.59433498 1.134995566 1 10.93062557 -9.215158751 0.889725351 1.003484786 0.807997754 0.275508816 0.162931511 0.871801286 1.20864903 0.112845915 0.029486452 6.09E-10 9.215158751 -0.195487032 SQS(ph)LQDQPTR ddPTM_HeLa_Curcumin_4h_R1 2 SQSLQDQPTR 10 0 Q8N4C8;Q8N4C8-2;Q8N4C8-3 Q8N4C8 MINK1 Misshapen-like kinase 1 1 0 S(0.001)QS(0.999)LQDQPTR;S(0.005)QS(0.995)LQDQPTR ; 143.76 0.001257 30573000 4313.6 3772.1 4115.7 4268 4373.4 6758.6 5903.4 9620.1 4835.3 3509.2 TRUE FALSE FALSE 3972.174008 4098.143516 4268.231463 4250.340147 4321.250061 5356.790175 6069.033516 12553.2242 4304.879687 3631.144439 1.09391793 1.128609337 1.175450752 1.170523569 1.190051824 1.475234672 1.671383118 3.457098558 1.1855435 1 11.8262086 -1.8297768 0.88323239 1.070296926 199.9999998 0.980585649 0.096548912 12.78967231 0.151213585 0.014669944 4972.731353 0.014798688 1.8297768 198.9297029 up TDS(ph)QTIGDFATR ddPTM_HeLa_Curcumin_4h_R1 1 TDSQTIGDFATR 12 0 Q13480-2 Q13480-2 GAB1 GRB2-associated-binding protein 1 1 0 T(0.005)DS(0.902)QT(0.093)IGDFATR 186.29 3.12E-05 16520000 2173.4 1482.6 1768.1 1814.7 1940.3 2022.9 1961.1 1071 1727.2 1823.8 TRUE FALSE FALSE 2001.373097 1610.749338 1833.627341 1807.191252 1917.16319 1603.327737 2016.123188 1397.54297 1537.730481 1887.176914 1.060511647 0.853523231 0.971624508 0.957616235 1.015889488 0.849590584 1.068327602 0.740546877 0.814831121 1 10.88201396 -1.958171388 0.343722527 1.019248367 2.55E-18 0 0.108339348 26.73408606 0.622297022 0.025445393 15.86606656 0.011011047 1.958171388 -1.019248367 TDS(ph)VIIADQTPTPTR ddPTM_HeLa_Curcumin_4h_R1 1 TDSVIIADQTPTPTR 15 0 K7ELQ4;P17544-4;P17544-2;P17544;P17544-3;P17544-1;K7ESA4;P17544-5 K7ELQ4 ATF7 Cyclic AMP-dependent transcription factor ATF-7 1 0 T(0.033)DS(0.967)VIIADQTPTPTR 146.27 0.00071376 8911600 1941.1 1426.5 1983.5 2077.1 1612.8 2020.2 1971.2 1941.8 1383.9 1688.3 TRUE FALSE FALSE 1787.459887 1549.800304 2057.010255 2068.505511 1593.568413 1601.187748 2026.506567 2533.845881 1232.089632 1746.968299 1.023178204 0.88713705 1.177474288 1.184054405 0.912190802 0.916552263 1.16001336 1.450424648 0.705273034 1 10.77063771 -4.364997445 3.003349399 1.014708286 1.476444591 0.515198419 0.137740161 0.140619822 1.980064642 0.013341349 0.134194668 4.32E-05 4.364997445 0.461736305 TDS(ph)YSAGQSVEILDGVELGEPAHKK ddPTM_HeLa_Curcumin_4h_R1 2 TDSYSAGQSVEILDGVELGEPAHKK 25 1 B1AKQ2;B1AKP8;P42345 B1AKQ2 MTOR Serine/threonine-protein kinase mTOR 1 0 T(0.178)DS(0.77)Y(0.022)S(0.03)AGQSVEILDGVELGEPAHKK;T(0.196)DS(0.595)Y(0.09)S(0.109)AGQS(0.01)VEILDGVELGEPAHKK ; 155.54 6.01E-09 17498600 5930.1 4670.5 5080.5 5960.2 5428.6 5646.1 3271.5 2518.6 5315.8 5588.5 TRUE FALSE FALSE 5460.726328 5074.197209 5268.787799 5935.538272 5363.867491 4475.035215 3363.289485 3286.509546 4732.670039 5782.699959 0.944321228 0.877478902 0.911129375 1.026430269 0.927571468 0.773866057 0.581612311 0.568334786 0.818418744 1 12.49752753 -4.990042729 1.994074999 0.963724853 0.558833375 0.835742208 0.061557333 0.0652315 0.495484477 0.006818423 0.028347454 1.02E-05 4.990042729 -0.404891478 TDSREDEIS(ph)PPPPNPVVK ddPTM_HeLa_Curcumin_4h_R1 9 TDSREDEISPPPPNPVVK 18 1 K7EMU2;K7EMZ6;K7EIE5;K7EID3;K7EJ40;K7EK41;K7EPB2;P10644-2;P10644 K7EMU2 PRKAR1A "cAMP-dependent protein kinase type I-alpha regulatory subunit;cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed" 1 0 TDSREDEIS(1)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;T(0.003)DS(0.005)REDEIS(0.993)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;TDS(0.001)REDEIS(0.999)PPPPNPVVK;TDS(0.004)REDEIS(0.996)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK;TDSREDEIS(1)PPPPNPVVK ;;;;;;;; 176.68 9.56E-19 6460611000 32528.4 26832 28560.2 28742.5 29609.1 34282.1 26972 25955.1 34178.5 30369.5 TRUE FALSE FALSE 29953.74282 29151.23852 29618.66614 28623.57115 29256.03082 27171.60602 27728.76173 33868.69051 30429.20406 31424.83786 0.953186869 0.927649608 0.942524072 0.910858197 0.930984304 0.864653817 0.882383605 1.077768186 0.968316979 1 14.93961768 -8.213199109 0.655681519 0.996656892 0.927113631 0.099713719 0.054755013 0.775590387 0.733854454 0.023765208 0.013481693 6.12E-09 8.213199109 -0.06954326 TDSTESSGTQS(ph)PKR ddPTM_HeLa_Curcumin_4h_R1 2 TDSTESSGTQSPKR 14 1 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 TDSTESSGTQS(1)PKR;TDSTESSGTQS(0.999)PKR ; 151.11 0.00076279 3953000 2390 3009.8 2379 2051.37 2157.94 2674.9 1845.89 945.81 2681.6 2684.5 TRUE FALSE FALSE 2200.828978 3269.953701 2467.167833 2042.881974 2132.207975 2120.095588 1897.680705 1234.183115 2387.435189 2777.786175 0.792296037 1.177179774 0.888177735 0.735435288 0.76759255 0.763232104 0.683162989 0.444304578 0.85947407 1 11.43971983 -3.838069447 0.472167492 0.925587123 5.29E-18 0.635757367 0.111145083 3.497345133 0.394843405 0.026755224 1.96322801 0.000145188 3.838069447 -0.925587123 AEGDSAGTAGT(ph)PGGTPAGDK ddPTM_HeLa_Curcumin_4h_R1 1 AEGDSAGTAGTPGGTPAGDK 20 0 J3KMX2;B9EGA3;Q92925-3;Q92925-2;Q92925 J3KMX2 SMARCD2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 1 0 AEGDSAGT(0.065)AGT(0.931)PGGT(0.004)PAGDK 260.49 5.71E-104 0 925.54 624.64 953.63 814.61 888.53 1266.2 1271.3 2051.3 519.18 447.26 TRUE FALSE FALSE 852.2825324 678.6310983 988.9723667 811.2393597 877.9348601 1003.575847 1306.969256 2676.731927 462.2272529 462.8022517 1.841569546 1.466352196 2.136922115 1.752885507 1.896997815 2.168476586 2.824033919 5.783748711 0.998757571 1 8.854252073 -1.810440068 0.758959643 1.479727867 200 0.933485082 0.337031093 18.60090038 0.28508816 0.063461137 6055.03285 0.01547248 1.810440068 198.5202721 up TDSVKT(ph)PESEGNPLLEQLEK ddPTM_HeLa_Curcumin_4h_R1 1 TDSVKTPESEGNPLLEQLEK 20 1 Q8WYK2;Q8WYK2-2 Q8WYK2 JDP2 Jun dimerization protein 2 1 0 T(0.074)DS(0.225)VKT(0.598)PES(0.103)EGNPLLEQLEK 61.904 0.011666 8948400 4734.8 4233.7 4457 4679.3 4940.3 5757.9 4564.9 4476.6 5232.7 4667.3 TRUE FALSE FALSE 4360.035584 4599.642163 4622.180341 4659.938296 4881.390149 4563.646635 4692.978808 5841.494732 4658.685902 4829.488328 0.902794517 0.952407761 0.957074544 0.964892755 1.010746857 0.944954481 0.971734165 1.209547334 0.964633432 1 12.23765463 -4.26168315 4.815102008 0.957595031 1.223384452 0.873159096 0.028139039 0.058856124 3.91288528 0.005330633 0.052199532 5.47E-05 4.26168315 0.265789422 TDTAVQAT(ph)GSVPS(ph)TPIAHR ddPTM_HeLa_Curcumin_4h_R1 1 TDTAVQATGSVPSTPIAHR 19 0 I3L533;I3L2R9;Q9NXR1;Q9NXR1-1;I3L2R3;I3L522 I3L533 NDE1 Nuclear distribution protein nudE homolog 1 2 0 TDTAVQAT(0.524)GS(0.524)VPS(0.729)T(0.224)PIAHR 123.64 0.00018679 9627100 2592.3 2514.4 2758.5 2697 3235 4346.6 5124 2859 2680.2 2354.5 TRUE FALSE FALSE 2387.11672 2731.733532 2860.732437 2685.840529 3196.424738 3445.066164 5267.765649 3730.695939 2386.188766 2436.3187 0.979804785 1.121254593 1.174202881 1.102417565 1.311989576 1.414045775 2.162182497 1.531284039 0.979423901 1 11.25048715 -5.277198981 1.24928944 1.014575237 1.859338961 0.737648235 0.176477359 0.159846233 0.447926073 0.024731218 0.106284143 5.28E-06 5.277198981 0.844763724 TDTAVQAT(ph)GSVPST(ph)PIAHR ddPTM_HeLa_Curcumin_4h_R1 1 TDTAVQATGSVPSTPIAHR 19 0 I3L533;I3L2R9;Q9NXR1;Q9NXR1-1;I3L2R3;I3L522 I3L533 NDE1 Nuclear distribution protein nudE homolog 1 2 0 T(0.001)DT(0.004)AVQAT(0.708)GS(0.294)VPS(0.316)T(0.677)PIAHR 93.712 0.0023251 9685400 970.49 1208.2 832.45 1336.5 1204.5 1829 2120.8 978.42 1002.7 1034 TRUE FALSE FALSE 893.6746924 1312.631424 863.3013293 1330.969917 1190.137124 1449.644783 2180.30394 1276.735754 892.7063186 1069.931423 0.835263525 1.226836969 0.806875385 1.243976846 1.112348977 1.354895044 2.037797838 1.193287463 0.834358445 1 10.06330262 -5.404806048 1.296530087 0.94485315 1.624503257 0.507448758 0.241592889 0.243185032 0.764123383 0.034068838 0.123778466 3.94E-06 5.404806048 0.679650107 TDTESELDLISR ddPTM_HeLa_Curcumin_4h_R1 4 TDTESELDLISR 12 0 V9GZ78;V9GYY3;A0A384N5Y3;F5H2F4;P11586;A0A494C1T2 V9GZ78 MTHFD1 "C-1-tetrahydrofolate synthase, cytoplasmic;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase;C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed" 0 0 ;;; ;;; 199.03 7.96E-06 26560700 8372.4 6624.8 6682.8 7035.57 7540.1 8162.8 7244.3 6970.35 7849.1 7539.4 FALSE FALSE TRUE 7709.715705 7197.418192 6930.470447 7006.458676 7450.189232 6469.743266 7447.555561 9095.577627 6988.073367 7801.393589 0.988248525 0.922581089 0.888363133 0.898103473 0.954981844 0.829306097 0.954644254 1.165891392 0.895746803 1 12.92951615 -7.332153146 5.744711763 0.994741895 0.937245056 0 0.088621468 0.412446267 25.26268622 0.013975401 0.015961769 4.65E-08 7.332153146 -0.057496839 TDTGEPMGR ddPTM_HeLa_Curcumin_4h_R1 2 TDTGEPMGR 9 0 P07900;P07900-2 P07900 HSP90AA1 Heat shock protein HSP 90-alpha 0 0 ; ; 105.14 0.0052091 13523600 4881.3 4620.8 4431 4508.6 4409.4 5223.2 4136.4 4197.7 4514.7 4046.9 FALSE FALSE TRUE 4494.939954 5020.201362 4595.216758 4489.944608 4356.820785 4139.849442 4252.456251 5477.559406 4019.448705 4187.529474 1.073410941 1.198845619 1.097357472 1.072218031 1.040427491 0.988613804 1.015504793 1.308064681 0.959861592 1 12.03188363 -8.591674699 0.999770875 1.008208073 1.091511944 0.201084153 0.08993656 0.734837593 1.489469146 0.032494743 0.017526185 2.56E-09 8.591674699 0.083303871 TDTGIVTVEQS(ph)PSSSK ddPTM_HeLa_Curcumin_4h_R1 1 TDTGIVTVEQSPSSSK 16 0 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 TDTGIVT(0.004)VEQS(0.983)PS(0.01)S(0.001)S(0.001)K 229.02 8.39E-22 83875000 6763.1 5381.3 6133.9 6186.1 6467.6 8335.4 7481.2 4426.4 6597.4 5718.1 TRUE FALSE FALSE 6227.793499 5846.435593 6361.22773 6160.503557 6390.478094 6606.544081 7691.102337 5775.988983 5873.681726 5916.803549 1.052560466 0.988107099 1.075112208 1.041187781 1.080055817 1.116573168 1.299874548 0.976200906 0.992711973 1 12.53060228 -5.498262724 1.932897429 1.026704939 1.148478224 0.272294795 0.077270446 0.285167272 2.096031442 0.010445637 0.027658588 3.17E-06 5.498262724 0.121773285 TDTPAPPTHALS(ph)QSPAEADGSVAFVPGEAQVAR ddPTM_HeLa_Curcumin_4h_R1 1 TDTPAPPTHALSQSPAEADGSVAFVPGEAQVAR 33 0 Q5SXM2 Q5SXM2 SNAPC4 snRNA-activating protein complex subunit 4 1 0 TDTPAPPTHALS(0.5)QS(0.5)PAEADGSVAFVPGEAQVAR 86.324 3.42E-08 7981000 716.7 517.3 375.3 543.53 718.84 708.44 777.53 765.62 505.77 660.68 TRUE FALSE FALSE 659.9724387 562.013107 389.2089481 541.2810169 710.2683025 561.5015582 799.3453992 999.0540135 450.2882964 683.6385808 0.965382085 0.822090974 0.569319753 0.791764877 1.038952924 0.821342701 1.169251446 1.461377461 0.658664255 1 9.417090007 -4.459717574 2.898577959 0.923881143 1.465796278 0.57026435 0.161095237 0.174757794 2.515742312 0.021759425 0.174335024 3.47E-05 4.459717574 0.541915135 TDTS(ph)PVLETAGTVAAMAATPSAR ddPTM_HeLa_Curcumin_4h_R1 1 TDTSPVLETAGTVAAMAATPSAR 23 0 Q8WWH5 Q8WWH5 TRUB1 Probable tRNA pseudouridine synthase 1 1 0 T(0.061)DT(0.313)S(0.562)PVLET(0.015)AGT(0.047)VAAMAAT(0.002)PSAR 105.01 0.00026016 0 1295.4 978.06 1186 1119.9 1184.3 1294.2 1283.1 1492.7 1299.4 1033.2 TRUE FALSE FALSE 1192.867723 1062.599148 1229.954203 1115.266151 1170.177996 1025.768331 1319.100333 1947.817358 1156.859071 1069.103623 1.115764363 0.993915955 1.150453685 1.043178721 1.094541231 0.95946577 1.233837679 1.821916338 1.082083201 1 10.06218598 -4.292926443 2.855231491 1.055410104 1.930073351 0.940934307 0.057611697 0.062073882 0.732313144 0.008301447 0.120778917 5.09E-05 4.292926443 0.874663247 TDVSNFDEEFTGEAPT(ph)LSPPRDAR ddPTM_HeLa_Curcumin_4h_R1 1 TDVSNFDEEFTGEAPTLSPPRDAR 24 1 Q16512;Q16512-2 Q16512 PKN1 Serine/threonine-protein kinase N1 1 0 TDVSNFDEEFT(0.157)GEAPT(0.498)LS(0.345)PPRDAR 77.543 0.00029585 17814000 1254.8 1119.4 1366.3 1330.5 1266.2 1325.4 1174.9 1021 1169.6 1032.2 TRUE FALSE FALSE 1155.481256 1216.155948 1416.93628 1324.994744 1251.101392 1050.4971 1207.864532 1332.2982 1041.297806 1068.068873 1.081841523 1.138649369 1.326633811 1.240551782 1.171367712 0.98354809 1.130886371 1.247389783 0.974935074 1 10.06078897 -7.550284574 1.637061631 1.027920614 1.175517779 0.415802009 0.087536323 0.297624075 1.605015419 0.018865213 0.019953244 2.82E-08 7.550284574 0.147597165 TDY(ph)DTREY(ph)SSS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 TDYDTREYSSSK 12 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;Q7Z6E9-4 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 3 0 T(0.245)DY(0.696)DT(0.086)REY(0.957)S(0.042)S(0.203)S(0.772)K 55.885 0.0091031 0 3888.3 2952.7 3251 4206.6 3875.4 3809.7 3016.9 2025.6 4754.9 3994 TRUE FALSE FALSE 3580.536952 3207.918231 3371.48492 4189.194204 3829.188386 3019.525276 3101.546094 2643.196115 4233.299366 4132.791203 0.866372574 0.776211058 0.815788835 1.013647677 0.92653807 0.730626138 0.750472488 0.639566817 1.024319681 1 12.01290076 -1.762395369 0.175337375 0.991413703 5.96E-36 0.561093448 0.083972428 29.75295279 0.403603034 0.131570497 7.436877449 0.017282423 1.762395369 -0.991413703 TDYIPLLDVDEKTGNS(ph)ESK ddPTM_HeLa_Curcumin_4h_R1 2 TDYIPLLDVDEKTGNSESK 19 1 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;H7C456;A0A0J9YW37;A0A0J9YVV8;P27816-7 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 TDYIPLLDVDEKT(0.074)GNS(0.869)ES(0.058)K;TDYIPLLDVDEKT(0.03)GNS(0.723)ES(0.247)K ; 85.884 0.0013245 87132000 3802.2 2954 3197.8 3986.5 3323 6933.2 6670.9 3393.7 4462.7 3287.1 TRUE FALSE FALSE 3501.251858 3209.330597 3316.313281 3970.004919 3283.375395 5495.176167 6858.0675 4428.423507 3973.152975 3401.32648 1.029378355 0.943552645 0.975005869 1.167193135 0.965322034 1.615597973 2.016292038 1.30196955 1.168118673 1 11.73188178 -5.226947571 5.593925969 1.014443234 1.690046676 0.70912424 0.177961396 0.061174092 5.510836039 0.021179725 0.053980898 5.93E-06 5.226947571 0.675603442 TDYNAS(ph)VSVPDSSGPER ddPTM_HeLa_Curcumin_4h_R1 1 TDYNASVSVPDSSGPER 17 0 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 0 TDYNAS(0.995)VS(0.005)VPDSSGPER 149.24 0.00023305 9302500 1037.7 972.52 1081.8 982.41 1071.6 1362.9 1154 1271.7 1128.6 1024.4 TRUE FALSE FALSE 955.56495 1056.580295 1121.89246 978.3450477 1058.82187 1080.219177 1186.378134 1659.435476 1004.795404 1059.997824 0.901478219 0.99677591 1.058391286 0.922968921 0.998890607 1.019076787 1.119226953 1.56550838 0.947922138 1 10.04984559 -3.785637975 1.227446456 0.963496351 2.682506731 0.941943044 0.043640379 0.745956476 0.421820996 0.007593332 2.162558397 0.000163818 3.785637975 1.71901038 TDYNASVSVPDS(ph)SGPER ddPTM_HeLa_Curcumin_4h_R1 2 TDYNASVSVPDSSGPER 17 0 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 1 0 TDYNASVSVPDS(0.75)S(0.249)GPER;TDYNAS(0.055)VS(0.316)VPDS(0.574)S(0.055)GPER ; 124.73 0.0004468 18530800 2338.2 2340.69 2444.3 2380.37 2299.29 3560.4 2943.44 3079.6 2635.96 2321.71 TRUE FALSE FALSE 2153.129003 2543.008814 2534.887908 2370.52066 2271.872468 2821.932906 3026.025005 4018.555863 2346.801783 2402.38925 0.896244854 1.058533214 1.055152869 0.986734627 0.945672092 1.174636003 1.259589804 1.672733036 0.97686159 1 11.23025421 -2.864424183 0.698633663 0.961848531 6.105052007 0.930627218 0.056860535 3.087211772 0.23292614 0.010701784 19.5872263 0.001366394 2.864424183 5.143203476 TDYNASVSVPDSSGPER ddPTM_HeLa_Curcumin_4h_R1 2 TDYNASVSVPDSSGPER 17 0 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 0 ; ; 390.56 0 24613000 5093.1 3143.8 4011.8 4019.9 3932.4 5707.1 3942.9 3722.2 4394.4 3661.9 FALSE FALSE TRUE 4689.975761 3415.536063 4160.480837 4003.266719 3885.508698 4523.383128 4053.527162 4857.081645 3912.345314 3789.150752 1.23773797 0.901398832 1.097998235 1.05650764 1.025429958 1.193772279 1.069771943 1.281839114 1.032512447 1 11.88765882 -2.069760575 1.476999017 1.09152615 135.2142052 0.285464368 0.093418661 1266.035332 5.006943304 0.015861057 573812.6395 0.008516074 2.069760575 134.122679 TEADAEK(ac)TFEEK ddPTM_HeLa_Curcumin_4h_R1 1 TEADAEKTFEEK 12 1 P19338;H7BY16 P19338 NCL Nucleolin 0 1 TEADAEK(1)TFEEK 115.78 0.0014295 5068500 1121.7 1443.7 977.98 1164.8 1966.1 2851.8 1946.3 1781.1 2555.9 864 FALSE TRUE FALSE 1032.916261 1568.486995 1014.224799 1159.980366 1942.655542 2260.304534 2000.90794 2324.149191 2275.524165 894.0239357 1.155356384 1.754412754 1.134449268 1.29748245 2.172934598 2.528237157 2.238092136 2.599649851 2.545260897 1 9.804169647 -5.731908018 2.855599997 1.141460921 2.431839975 0.355237045 0.494409749 0.0664581 1.108052725 0.03517061 0.073262571 1.85E-06 5.731908018 1.290379054 TEADAEKTFEEK ddPTM_HeLa_Curcumin_4h_R1 1 TEADAEKTFEEK 12 1 P19338;H7BY16 P19338 NCL Nucleolin 0 0 92.112 0.011824 44438000 2485 1750 2168.7 2016.7 1860.4 3130 2115 2086.3 2877.5 2508.3 FALSE FALSE TRUE 2288.309628 1901.262202 2249.07393 2008.35543 1838.215945 2480.802718 2174.341208 2722.403266 2561.845449 2595.463238 0.881657499 0.732532896 0.866540468 0.773794597 0.70824195 0.955822714 0.837746871 1.048908428 0.98704748 1 11.34177634 -8.490296084 0.940682173 0.986196773 0.844191821 0.255127738 0.09634955 0.487914431 0.887155892 0.035069186 0.019694455 3.23E-09 8.490296084 -0.142004952 RSSAWAEGGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 RSSAWAEGGSPR 12 1 Q8N9B5-2;Q8N9B5 Q8N9B5-2 JMY Junction-mediating and -regulatory protein 1 0 RSSAWAEGGS(1)PR 95.195 0.0056182 4846300 2708.2 2109.2 1886.9 2132.1 2142.2 2661.1 1861 716.51 2382 2048.3 TRUE FALSE FALSE 2493.843112 2291.50985 1956.830174 2123.277935 2116.655664 2109.157863 1913.214651 934.9706006 2120.700559 2119.478273 1.176630657 1.081166945 0.923260313 1.001792735 0.998668253 0.995130684 0.902681889 0.44113243 1.000576692 1 11.04949346 -4.086690183 1.402990901 1.061278455 9.75E-19 0.856885263 0.07001895 0.580773966 0.740894537 0.012942353 0.969820053 8.19E-05 4.086690183 -1.061278455 down TEAELSQDLETS(ph)PTAKPQIK ddPTM_HeLa_Curcumin_4h_R1 1 TEAELSQDLETSPTAKPQIK 20 1 Q5VT06;H0Y7F7 Q5VT06 CEP350 Centrosome-associated protein 350 1 0 TEAELS(0.003)QDLET(0.354)S(0.639)PT(0.003)AKPQIK 83.245 0.00097522 10895000 3567.4 2858.7 3069 3110.9 2810.8 3860.7 2567.7 1173.3 3879.7 2788.9 TRUE FALSE FALSE 3285.036526 3105.79329 3182.73984 3098.02792 2777.283046 3059.947301 2639.742751 1531.033769 3454.106617 2885.814067 1.138339633 1.076227788 1.102891512 1.073536911 0.96239154 1.060341113 0.91473071 0.530537912 1.196926252 1 11.49476263 -4.007279477 1.403641375 1.066109457 3.46E-12 0.874866659 0.062496399 0.543533221 0.598421113 0.008775011 0.964550341 9.83E-05 4.007279477 -1.066109457 IYS(ph)S(ph)Y(ph)PKVQET(ph)LPVTY(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 IYSSYPKVQETLPVTYK 17 1 Q9NR99 Q9NR99 MXRA5 Matrix-remodeling-associated protein 5 5 0 IY(0.093)S(0.924)S(0.957)Y(0.956)PKVQET(0.947)LPVT(0.19)Y(0.933)K 47.301 0.016153 25431000 2489.8 1880.6 2358.5 2459.6 2619.6 2814.8 2617.4 3442 1883.2 1892.2 TRUE FALSE FALSE 2292.729703 2043.150684 2445.908085 2449.422827 2588.362981 2230.978751 2690.8372 4491.449955 1676.617672 1957.953809 1.170982529 1.04351322 1.249216439 1.251011549 1.321973465 1.139444016 1.374310868 2.293950927 0.856311147 1 10.93513101 -1.782361263 1.00179203 1.111602507 200 0.878805785 0.129560067 60.38719779 0.463133568 0.018121745 27096.83845 0.016505882 1.782361263 198.8883975 up TEAPAPASSTPQEPWPGPTAPS(ph)PTSRPPWAVDPAFAER ddPTM_HeLa_Curcumin_4h_R1 1 TEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAER 38 1 Q9NR12-2;Q9NR12 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 1 0 TEAPAPASSTPQEPWPGPT(0.376)APS(0.471)PT(0.077)S(0.077)RPPWAVDPAFAER 78.415 1.12E-09 17910000 1602.5 1378.8 1692.4 1529.8 1633.9 2235.9 1895.2 3120.9 1933.2 2007.9 TRUE FALSE FALSE 1475.660434 1497.977328 1755.121833 1523.470093 1614.41681 1772.149136 1948.374211 4072.448043 1721.132797 2077.674376 0.71024625 0.720987536 0.844753082 0.733257391 0.777030717 0.852948449 0.937766877 1.960099278 0.828393909 1 11.02075385 -4.255239718 3.670468208 0.834020242 2.091094693 0.943942932 0.08348227 0.065850269 1.611755838 0.016766801 0.226889546 5.56E-05 4.255239718 1.25707445 TEAQDLCRAS(ph)PEPPGPESSSR ddPTM_HeLa_Curcumin_4h_R1 4 TEAQDLCRASPEPPGPESSSR 21 1 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 TEAQDLCRAS(1)PEPPGPESSSR;TEAQDLCRAS(1)PEPPGPESSSR;TEAQDLCRAS(0.997)PEPPGPESS(0.001)S(0.002)R;T(0.001)EAQDLCRAS(0.999)PEPPGPESSSR ;;; 99.943 7.44E-05 1319039000 8205.4 6806.2 6430.6 7112.4 5986.2 6895.6 4528 4413.63 9504 7638.5 TRUE FALSE FALSE 7555.933932 7394.4976 6668.923693 7082.970773 5914.818475 5465.374831 4655.043494 5759.325469 8461.434978 7903.937306 0.955970884 0.935546085 0.843747038 0.896131953 0.748338233 0.691474972 0.588952482 0.728665379 1.070534172 1 12.94835579 -5.856383889 0.678855802 0.984246855 0.625162567 0.865775192 0.053093977 0.174380515 0.142721744 0.008619377 0.032516536 1.39E-06 5.856383889 -0.359084288 TEARS(ph)S(ph)DEENGPPS(ph)SPDLDR ddPTM_HeLa_Curcumin_4h_R1 2 TEARSSDEENGPPSSPDLDR 20 1 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 3 0 T(0.25)EARS(0.875)S(0.875)DEENGPPS(0.702)S(0.298)PDLDR;T(0.434)EARS(0.836)S(0.732)DEENGPPS(0.512)S(0.486)PDLDR ; 90.581 0.00074082 48758000 2845.3 2478.2 2378.29 2365.36 2184.56 2934.6 2185.2 1604.01 3057.1 2291.28 TRUE FALSE FALSE 2620.091503 2692.404565 2466.43152 2355.572767 2158.510549 2325.93088 2246.510831 2093.065265 2721.743778 2370.901809 1.105103338 1.135603573 1.040292563 0.99353451 0.910417521 0.981032142 0.947534319 0.882813981 1.147978279 1 11.2112202 -6.076761111 2.71854591 1.05824161 0.935501502 0.660391238 0.050732018 0.16589602 2.407074883 0.008269395 0.014933722 8.38E-07 6.076761111 -0.122740108 TEARSS(ph)DEENGPPS(ph)SPDLDR ddPTM_HeLa_Curcumin_4h_R1 1 TEARSSDEENGPPSSPDLDR 20 1 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 2 0 T(0.161)EARS(0.379)S(0.46)DEENGPPS(0.547)S(0.453)PDLDR 84.312 0.0015064 93996000 1279.5 942.36 1091.6 1314.1 1149.4 1178.5 1050 1040.7 1388.8 1021.4 TRUE FALSE FALSE 1178.226225 1023.813399 1132.055656 1308.662602 1135.694156 934.0658156 1079.460174 1358.004639 1236.452115 1056.893574 1.1148012 0.968700562 1.071116037 1.238216065 1.074558672 0.883784175 1.021351819 1.284901974 1.169892736 1 10.04561439 -9.521384816 1.190610635 0.99863433 1.07901212 0 0.122645181 1.244335732 3.068805973 0.084498842 0.018881277 3.01E-10 9.521384816 0.08037779 TEARSS(ph)DEENGPPSS(ph)PDLDR ddPTM_HeLa_Curcumin_4h_R1 1 TEARSSDEENGPPSSPDLDR 20 1 Q96B36-3;Q96B36;Q96B36-2 Q96B36-3 AKT1S1 Proline-rich AKT1 substrate 1 2 0 T(0.021)EARS(0.451)S(0.528)DEENGPPS(0.263)S(0.737)PDLDR 80.355 0.0019479 81409000 1326.4 1229.9 1128.5 1375.1 1011.4 1477.3 1418.6 1130.9 1332.8 1224.9 TRUE FALSE FALSE 1221.41404 1336.207076 1170.323203 1369.410201 999.3397156 1170.891327 1458.402098 1475.706204 1186.595175 1267.465184 0.963666739 1.054235724 0.923357278 1.080432203 0.788455358 0.923805515 1.150644701 1.164297231 0.936195479 1 10.3077304 -4.75026963 24.550405 0.973273932 1.157471149 0.508602235 0.077077236 105.9281755 232817.5329 0.010048219 0.036869857 1.78E-05 4.75026963 0.184197217 TEATQGLDYVPS(ph)AGTISPTSSLEEDKGFK ddPTM_HeLa_Curcumin_4h_R1 1 TEATQGLDYVPSAGTISPTSSLEEDKGFK 29 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 TEATQGLDY(0.008)VPS(0.847)AGT(0.143)IS(0.001)PTSSLEEDKGFK 136.3 3.50E-12 6061200 3805.6 2904 2963 3027.7 2884 3530.1 2927.1 4364.9 3671.5 3154.5 TRUE FALSE FALSE 3504.382744 3155.00882 3072.811387 3015.17218 2849.610184 2797.917468 3009.226548 5695.737916 3268.745636 3264.11864 1.073607651 0.966572961 0.941390839 0.92373241 0.873010603 0.85717395 0.921910898 1.744954318 1.001417533 1 11.67247778 -4.258349052 24.99770603 0.988969887 1.744954596 0.917610209 0.070551493 76.59117077 619516.1693 0.012594629 0.119415479 5.52E-05 4.258349052 0.755984709 TEDEEFLIQHLLQAPS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 2 TEDEEFLIQHLLQAPSPPR 19 0 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 0 TEDEEFLIQHLLQAPS(1)PPR;TEDEEFLIQHLLQAPS(1)PPR ; 124.1 8.37E-05 240322400 3153.14 3157.84 3548.5 3438.95 4429.2 3872.9 3307.7 1145.43 2831.74 3193.01 TRUE FALSE FALSE 2903.565642 3430.789619 3680.010532 3424.720536 4376.384683 3069.616883 3400.50516 1494.666334 2521.105207 3303.96686 0.878811975 1.038384997 1.113815812 1.036548089 1.324584921 0.929070119 1.029218907 0.452385389 0.763054024 1 11.6899835 -4.259204812 24.85318151 0.994598138 0.452385185 0.583764605 0.141181458 99.51073909 1106690.854 0.018377358 0.163785736 5.51E-05 4.259204812 -0.542212953 TEDEEFLIQHLLQAPS(ph)PPRTSGADGLVGEDGAADASK ddPTM_HeLa_Curcumin_4h_R1 1 TEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASK 37 1 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 1 0 TEDEEFLIQHLLQAPS(0.776)PPRT(0.112)S(0.112)GADGLVGEDGAADASK 79.018 9.93E-09 3731800 1125 686.25 832.82 1044.9 680.08 1213.8 556.9 302.83 1474.5 1131.4 TRUE FALSE FALSE 1035.955063 745.5663921 863.6850418 1040.576481 671.9704902 962.0441977 572.5251152 395.1614729 1312.751039 1170.716066 0.884890105 0.636846469 0.73774083 0.888837619 0.573982462 0.821757065 0.489038403 0.337538268 1.121323161 1 10.19317551 -4.3276488 0.233661587 1.018266975 7.99E-14 0.696411488 0.126266184 4.604192419 0.214680108 0.100360655 1.368911308 4.70E-05 4.3276488 -1.018266975 TEDEEFLIQHLLQAPSPPR ddPTM_HeLa_Curcumin_4h_R1 1 TEDEEFLIQHLLQAPSPPR 19 0 Q9ULL5;Q9ULL5-2 Q9ULL5 PRR12 Proline-rich protein 12 0 0 130.01 0.00012048 3390700 1559.1 1250.4 1568.7 1269.7 1977.8 1988.4 1389.5 562.46 1627.6 1477.9 FALSE FALSE TRUE 1435.69559 1358.479004 1626.837402 1264.446318 1954.216027 1575.983426 1428.48563 733.9514648 1449.056352 1529.256915 0.938819093 0.888326213 1.063809087 0.826837077 1.277886016 1.030555043 0.934104411 0.479939935 0.947555861 1 10.57861508 -4.264886419 3.955011117 0.98602361 0.434853463 0.641564033 0.114928525 0.108968628 3.481182778 0.014983064 0.171333469 5.43E-05 4.264886419 -0.551170147 SRTDSLAAT(ph)PPAAK ddPTM_HeLa_Curcumin_4h_R1 1 SRTDSLAATPPAAK 14 1 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 SRTDSLAAT(1)PPAAK 102.36 0.0034982 64279000 3850.3 3234.9 3726.7 3284.3 2834.1 3666.1 2820.6 962.44 4189.9 3231.9 TRUE FALSE FALSE 3545.544692 3514.510342 3864.81478 3270.710437 2800.305209 2905.709535 2899.738445 1255.883525 3730.278453 3344.208284 1.060204506 1.050924477 1.155674064 0.978022347 0.837359689 0.868878158 0.867092656 0.375539864 1.115444415 1 11.70744899 -4.085780463 0.856999237 1.032323327 2.76E-21 0.829775123 0.087307282 0.876233073 0.387087121 0.013277607 0.911500816 8.21E-05 4.085780463 -1.032323327 down TEDGDWEWS(ph)DDEMDEK ddPTM_HeLa_Curcumin_4h_R1 3 TEDGDWEWSDDEMDEK 16 0 Q9UEW8-2;Q9UEW8 Q9UEW8-2 STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1 0 TEDGDWEWS(1)DDEMDEK;TEDGDWEWS(1)DDEMDEK;TEDGDWEWS(1)DDEMDEK ;; 204.67 2.32E-10 43214000 10619.2 9915.4 11561.7 9271 12807.8 11005.3 9390.7 8181.9 8985.5 8798.4 TRUE FALSE FALSE 9778.679115 10772.44299 11990.18677 9232.639058 12655.07535 8722.676725 9654.177768 10676.52365 7999.813131 9104.143745 1.074091028 1.183246145 1.317003236 1.014113937 1.390034659 0.958099627 1.060415789 1.172710355 0.878700222 1 13.15230762 -7.626567532 2.0226199 1.025929265 1.153704601 0.249035347 0.131970174 0.37136505 3.143687786 0.023251925 0.024022526 2.36E-08 7.626567532 0.127775336 TEDGDWEWS(ph)DDEMDEKSEEGK ddPTM_HeLa_Curcumin_4h_R1 10 TEDGDWEWSDDEMDEKSEEGK 21 1 Q9UEW8-2;Q9UEW8 Q9UEW8-2 STK39 STE20/SPS1-related proline-alanine-rich protein kinase 1 0 TEDGDWEWS(1)DDEMDEKSEEGK;TEDGDWEWS(1)DDEMDEKSEEGK;TEDGDWEWS(1)DDEMDEKSEEGK;TEDGDWEWS(1)DDEMDEKSEEGK;TEDGDWEWS(1)DDEMDEKSEEGK;TEDGDWEWS(1)DDEMDEKSEEGK;TEDGDWEWS(1)DDEMDEKSEEGK;T(0.06)EDGDWEWS(0.939)DDEMDEKS(0.001)EEGK;T(0.002)EDGDWEWS(0.998)DDEMDEKSEEGK;T(0.001)EDGDWEWS(0.998)DDEMDEKS(0.001)EEGK ;;;;;;;;; 135.31 1.54E-05 946129500 33253.9 27795.39 30808.5 30046.2 30967.1 33712.1 27618.87 26613.97 33684.3 29299.1 TRUE FALSE FALSE 30621.81873 30197.89966 31950.29011 29921.87679 30597.83756 26719.83045 28393.78116 34728.44694 29989.21656 30317.24154 1.010046336 0.996063564 1.053865341 0.986959079 1.009255328 0.881341081 0.936555561 1.145501542 0.98918025 1 14.88785087 TEDGGWEWS(ph)DDEFDEESEEGK ddPTM_HeLa_Curcumin_4h_R1 3 TEDGGWEWSDDEFDEESEEGK 21 0 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 0 TEDGGWEWS(1)DDEFDEESEEGK;TEDGGWEWS(1)DDEFDEESEEGK;T(0.025)EDGGWEWS(0.975)DDEFDEESEEGK ;; 198.45 9.18E-14 27589000 18777.04 15470.17 19558.66 18077.22 23396.95 19199.18 18098.93 15133.92 15121.65 14690.05 TRUE FALSE FALSE 17290.81747 16807.34256 20283.52115 18002.42125 23117.95665 15217.05365 18606.73727 19748.18254 13462.84283 15200.52814 1.137514257 1.105707802 1.334395815 1.184328668 1.520865356 1.001087166 1.224084919 1.299177394 0.88568257 1 13.89183383 -7.766061101 0.632817904 1.018306662 1.254409261 0.41254051 0.135687372 0.527509167 0.4809253 0.04583926 0.037088652 1.71E-08 7.766061101 0.236102599 TEDGGWEWS(ph)DDEFDEESEEGKAAISQLR ddPTM_HeLa_Curcumin_4h_R1 1 TEDGGWEWSDDEFDEESEEGKAAISQLR 28 1 C9JIG9;O95747 C9JIG9 OXSR1 Serine/threonine-protein kinase OSR1 1 0 T(0.001)EDGGWEWS(0.914)DDEFDEES(0.084)EEGKAAIS(0.001)QLR 52.255 0.0044511 12902000 919.16 685.87 1010.4 847.08 865.68 1133.5 637.75 674.84 887.12 802.4 TRUE FALSE FALSE 846.4075161 745.1535466 1047.846313 843.5750074 855.3573314 898.3993228 655.6435486 880.5956094 789.8051555 830.2833403 1.019420088 0.897468985 1.262034612 1.016008592 1.030199319 1.082039443 0.789662416 1.060596506 0.951247745 1 9.697459941 -4.798286921 24.99971125 1.025330814 0.92512808 0.13172743 0.108890516 211.9830998 143822.5555 0.013564982 0.040696563 1.59E-05 4.798286921 -0.100202734 TEDSIRDYEDGMEVDT(ph)TPTVAGQFEDADVDH ddPTM_HeLa_Curcumin_4h_R1 2 TEDSIRDYEDGMEVDTTPTVAGQFEDADVDH 31 1 P54105;E9PMI6;J3KN38 P54105 CLNS1A Methylosome subunit pICln 1 0 TEDSIRDYEDGMEVDT(0.484)T(0.484)PT(0.031)VAGQFEDADVDH;TEDSIRDYEDGMEVDT(0.421)T(0.421)PT(0.158)VAGQFEDADVDH ; 92.664 3.63E-08 27834000 2530.22 2208.04 2356.61 2409.01 2209.79 3781.76 2679.47 2244.45 2662.21 2136.05 TRUE FALSE FALSE 2329.950417 2398.893139 2443.94804 2399.042155 2183.439698 2997.380347 2754.648717 2928.772473 2370.172224 2210.277579 1.054143805 1.085335689 1.105719962 1.085403109 0.987857688 1.356110371 1.246290848 1.325069983 1.072341432 1 11.11001185 -5.261675336 24.99999997 1.039307625 1.302870454 0.865171191 0.045481953 5.403233588 572521.7214 0.006925147 0.016455277 5.47E-06 5.261675336 0.263562829 TEDSIRDYEDGMEVDTTPTVAGQFEDADVDH ddPTM_HeLa_Curcumin_4h_R1 6 TEDSIRDYEDGMEVDTTPTVAGQFEDADVDH 31 1 P54105;E9PMI6;J3KN38 P54105 CLNS1A Methylosome subunit pICln 0 0 ;;;;; ;;;;; 223.57 2.71E-35 182773000 8456.66 6875.51 6089.62 7359.26 7218.34 8898.99 6336.76 6480.81 8493.74 7147.94 FALSE FALSE TRUE 7787.306438 7469.798448 6315.306674 7328.809332 7132.26601 7053.239162 6514.552431 8456.779135 7561.997972 7396.330383 1.052860815 1.009933043 0.853843237 0.990871007 0.964297921 0.953613319 0.880781698 1.143374984 1.022398619 1 12.85259395 -6.979151703 24.99924306 1.025300747 0.958903612 0.126048934 0.073251287 317.2619194 380428.5347 0.011001153 0.014457696 1.05E-07 6.979151703 -0.066397135 TEDSLMPEEEFLRR ddPTM_HeLa_Curcumin_4h_R1 1 TEDSLMPEEEFLRR 14 1 Q15459;Q15459-2 Q15459 SF3A1 Splicing factor 3A subunit 1 0 0 159.66 0.00045096 5241700 953.94 863.26 876.14 912.38 1139.6 931.1 1219.7 1082.5 1145.1 836.65 FALSE FALSE TRUE 878.4346424 937.8763478 908.6105191 908.6048133 1126.011014 737.9793643 1253.921499 1412.549267 1019.485395 865.7235252 1.014682652 1.083343955 1.049538903 1.049532312 1.300658907 0.852442313 1.448408716 1.631640155 1.177610825 1 9.757762554 -4.620398477 5.030051262 1.031896808 1.589822585 0.729466106 0.115990187 0.056757031 2.273971209 0.013925851 0.056007889 2.40E-05 4.620398477 0.557925778 SGDEGS(ph)EDEAPS(ph)GED ddPTM_HeLa_Curcumin_4h_R1 1 SGDEGSEDEAPSGED 15 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 2 0 S(0.002)GDEGS(0.998)EDEAPS(1)GED 99.991 0.0021613 0 496.48 697.44 607.82 593.88 634.13 766.43 644.74 892.32 700.97 543.92 TRUE FALSE FALSE 457.1830841 757.7236059 630.3463439 591.4226819 626.5684139 607.4637786 662.8296692 1164.38426 624.0753447 562.8211795 0.812306112 1.346295473 1.119976232 1.050818099 1.113263745 1.07931933 1.177691411 2.068835187 1.108834151 1 9.136532809 -1.756798371 1.007561844 0.976747358 200 0.774714688 0.151932538 101.9337007 0.724539055 0.025771669 46108.46386 0.017506593 1.756798371 199.0232526 up GLPNGPTHAFSS(ph)PS(ph)ESPDSTVDR ddPTM_HeLa_Curcumin_4h_R1 1 GLPNGPTHAFSSPSESPDSTVDR 23 0 Q9ULJ7-2;Q9ULJ7 Q9ULJ7-2 ANKRD50 Ankyrin repeat domain-containing protein 50 2 0 GLPNGPT(0.094)HAFS(0.346)S(0.561)PS(0.702)ES(0.279)PDS(0.01)T(0.008)VDR 108.3 3.86E-05 10765000 1556.8 1173.4 1163.5 1313.4 1329.7 1491.5 1015 428.21 1673.2 1109.6 TRUE FALSE FALSE 1433.577637 1274.823467 1206.620334 1307.965499 1313.844196 1182.146087 1043.478168 558.7692578 1489.654146 1148.158517 1.248588601 1.110320089 1.050917896 1.139185469 1.144305578 1.02960181 0.908827616 0.486665603 1.29742899 1 10.16510612 -4.085728959 1.319514151 1.117563903 8.88E-12 0.845462929 0.084370725 0.614555946 0.684353468 0.0136683 1.024008287 8.21E-05 4.085728959 -1.117563903 down TEEARPSPAPGPGT(ph)PTGTPTR ddPTM_HeLa_Curcumin_4h_R1 6 TEEARPSPAPGPGTPTGTPTR 21 1 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 0 T(0.022)EEARPS(0.109)PAPGPGT(0.797)PT(0.064)GT(0.006)PT(0.002)R;TEEARPSPAPGPGT(0.939)PT(0.039)GT(0.02)PT(0.002)R;TEEARPS(0.025)PAPGPGT(0.959)PT(0.017)GTPTR;T(0.002)EEARPSPAPGPGT(0.91)PT(0.086)GT(0.001)PTR;TEEARPS(0.002)PAPGPGT(0.969)PT(0.028)GT(0.001)PTR;T(0.015)EEARPS(0.125)PAPGPGT(0.591)PT(0.225)GT(0.034)PT(0.01)R ;;;;; 111.81 2.49E-05 199912600 5031.4 3906.37 5062.76 4888.23 4970.87 5871.82 4632.89 2258.77 5570.51 4040.99 TRUE FALSE FALSE 4633.159381 4244.019216 5250.390339 4868.003799 4911.595622 4653.938343 4762.876425 2947.458575 4959.43899 4181.414102 1.108036484 1.014972235 1.255649455 1.164200359 1.174625498 1.113005847 1.139058775 0.704895163 1.186067409 1 12.02977521 -4.256715042 24.91176337 1.087527445 0.704895 0.682526452 0.082516974 238.372964 1256911.159 0.012404729 0.134519345 5.54E-05 4.256715042 -0.382632446 ITPHT(ph)SPAPR ddPTM_HeLa_Curcumin_4h_R1 1 ITPHTSPAPR 10 0 A0A0C4DFZ9;Q58A45-2;Q58A45-4;Q58A45-3;Q58A45 A0A0C4DFZ9 PAN3 PAB-dependent poly(A)-specific ribonuclease subunit PAN3 1 0 ITPHT(0.5)S(0.5)PAPR 124.48 0.0036006 9812000 1758.3 1728 1318.3 1604.2 1793.4 1694.2 1238.4 559.41 1942.4 1685.7 TRUE FALSE FALSE 1619.1287 1877.36062 1367.157358 1597.562245 1772.014876 1342.803822 1273.146171 729.9715338 1729.32358 1744.27795 0.928251544 1.076296711 0.783795586 0.915887428 1.015901667 0.769833628 0.729898679 0.418494962 0.991426613 1 10.76841424 -4.085717116 0.887322392 0.96231821 4.66E-19 0.811428002 0.080241565 0.834686963 0.396771913 0.012039325 0.835763434 8.21E-05 4.085717116 -0.96231821 down TEEARPSPAPGPGTPT(ph)GTPTR ddPTM_HeLa_Curcumin_4h_R1 1 TEEARPSPAPGPGTPTGTPTR 21 1 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 0 TEEARPSPAPGPGT(0.281)PT(0.657)GT(0.058)PT(0.003)R 119.48 1.11E-05 140900000 1329.4 1156.2 1064.8 1042.3 1282.8 1424 1013.2 420.9 1402.9 838.41 TRUE FALSE FALSE 1224.176587 1256.136776 1104.262425 1037.987239 1267.503448 1128.646348 1041.627665 549.2304724 1249.00538 867.5446851 1.411081882 1.447921701 1.27285942 1.196465446 1.461023818 1.300966241 1.200661687 0.63308609 1.439701495 1 9.760794259 -4.263189625 4.444187919 1.246895595 0.591696892 0.634559429 0.147492842 0.128900782 6.281551245 0.025556029 0.263658813 5.46E-05 4.263189625 -0.655198703 TEEGEIDYS(ph)AEEGENRR ddPTM_HeLa_Curcumin_4h_R1 1 TEEGEIDYSAEEGENRR 17 1 B7WPG3;V9GYK2;Q8WVV9-2;Q8WVV9-5;Q8WVV9;C9IYN3;Q8WVV9-3;Q8WVV9-4 B7WPG3 HNRNPLL Heterogeneous nuclear ribonucleoprotein L-like 1 0 TEEGEIDYS(1)AEEGENRR 93.269 0.001618 6248100 1659 1067.1 991.48 1081.9 1258.7 1442.8 1077.6 804.04 1175.4 1177.3 TRUE FALSE FALSE 1527.688399 1159.335369 1028.225121 1077.423384 1243.690825 1143.547016 1107.834556 1049.188095 1046.461561 1218.211087 1.254042436 0.951670348 0.844045118 0.884430782 1.0209157 0.938710071 0.909394576 0.861253116 0.85901497 1 10.25054842 -7.092168957 7.259267562 1.119699702 0.913596611 0.092988184 0.109987516 0.175174198 12.09116273 0.017178844 0.021090939 8.09E-08 7.092168957 -0.206103091 TEEGPTLSYGR ddPTM_HeLa_Curcumin_4h_R1 1 TEEGPTLSYGR 11 0 A0A0R4J2E8;A8MXP9;P43243;D6REM6;D6R991 A0A0R4J2E8 MATR3 Matrin-3 0 0 112.71 0.0037079 3004200 600.56 576.08 560.47 600.38 713.57 817.83 532.77 610.06 854.78 552.06 FALSE FALSE TRUE 553.0250423 625.8737882 581.2415112 597.8957866 705.0611438 648.2028392 547.7180923 796.0644856 761.0127726 571.2440439 0.968106448 1.095632935 1.017501219 1.046655616 1.234255571 1.134721396 0.958816286 1.393562864 1.332202551 1 9.157963408 -1 0.279508357 0.979589455 3.087842301 0 0.148258686 33.29007562 0.424156563 0.041290062 34.71691878 0.1 1 2.108252846 TEEK(ac)EIAAR ddPTM_HeLa_Curcumin_4h_R1 3 TEEKEIAAR 9 1 Q04727-4;Q04727;Q04727-3;H7C4W5;H7C4P7;Q5JSY7;H7C4E4;Q04727-2 Q04727-4 TLE4 Transducin-like enhancer protein 4 0 1 ;; TEEK(1)EIAAR;TEEK(1)EIAAR;TEEK(1)EIAAR 112.71 0.0026885 3084000 3608.48 3739.41 3676.79 3786.65 4256.73 5005.01 3799.17 3346.86 4533.4 3366.46 FALSE TRUE FALSE 3322.865 4062.627938 3813.055072 3770.981846 4205.971275 3966.914508 3905.764485 4367.302207 4036.097362 3483.444234 0.953902166 1.16626754 1.094622108 1.082544055 1.207417427 1.138790875 1.121236404 1.253731053 1.158651349 1 11.76629875 -7.260270984 24.99795057 0.978231577 1.147632282 0.229683 0.075244294 39.4646528 844353.0352 0.008224026 0.009773749 5.49E-08 7.260270984 0.169400706 TEELIES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 TEELIESPK 9 0 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 0 TEELIES(1)PK;TEELIES(1)PK ; 110.84 0.0088795 16721100 8700.5 9150.6 10012.7 8509.1 10923 9206.3 8102.2 9071.3 8709.7 7947.9 TRUE FALSE FALSE 8011.846244 9941.53709 10383.77947 8473.891599 10792.75036 7296.809604 8329.525926 11837.09761 7754.267701 8224.088933 0.974192559 1.208831418 1.262605445 1.030374509 1.312333858 0.887248382 1.012820507 1.439320234 0.94287255 1 13.00564015 -7.271065864 23.91841787 0.987813146 1.152537914 0.248167351 0.151736534 420.7609043 1045440.252 0.024428734 0.028132784 5.36E-08 7.271065864 0.164724769 TEELIES(ph)PKLES(ph)SEGEIIQTVDR ddPTM_HeLa_Curcumin_4h_R1 2 TEELIESPKLESSEGEIIQTVDR 23 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 2 0 TEELIES(1)PKLES(0.54)S(0.457)EGEIIQT(0.003)VDR;TEELIES(0.992)PKLES(0.539)S(0.462)EGEIIQT(0.007)VDR ; 78.942 0.0004297 63183000 8818.5 7840.2 8763.5 9602.2 9072 10482.7 9060 8193.6 9682 9096 TRUE FALSE FALSE 8120.50642 8517.871953 9088.283019 9562.468641 8963.822325 8308.469856 9314.199216 10691.79092 8619.908823 9412.085323 0.862774416 0.904993066 0.965597177 1.015977683 0.952373679 0.882744851 0.989599955 1.135964088 0.915834114 1 13.20029868 -6.55316546 7.31726238 0.931235438 0.98683318 0.202321225 0.067425711 0.349741381 63.87705524 0.01239409 0.017659594 2.80E-07 6.55316546 0.055597742 TEELIES(ph)PKLESSEGEIIQTVDR ddPTM_HeLa_Curcumin_4h_R1 5 TEELIESPKLESSEGEIIQTVDR 23 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 0 T(0.001)EELIES(0.999)PKLESSEGEIIQTVDR;T(0.017)EELIES(0.981)PKLES(0.001)S(0.001)EGEIIQTVDR;T(0.02)EELIES(0.959)PKLES(0.017)S(0.003)EGEIIQT(0.001)VDR;T(0.002)EELIES(0.977)PKLES(0.018)S(0.002)EGEIIQT(0.001)VDR;T(0.003)EELIES(0.993)PKLES(0.004)S(0.001)EGEIIQTVDR ;;;; 75.224 0.00045035 555142500 4797.13 3897.57 3949.31 4643.26 4633.13 4631.03 4031.07 3918.24 4666.92 4327.92 TRUE FALSE FALSE 4417.432099 4234.458584 4095.674903 4624.04742 4577.882951 3670.502176 4144.170975 5112.893339 4154.970552 4478.314898 0.986404976 0.945547305 0.914557148 1.032541821 1.022233375 0.819616811 0.925386238 1.141700272 0.927797765 1 12.12874026 -7.472391955 5.553623793 0.994166431 0.966015434 0 0.083094432 0.764542149 50.6312772 0.013689957 0.015311883 3.37E-08 7.472391955 -0.028150997 TEELIESPKLESS(ph)EGEIIQTVDR ddPTM_HeLa_Curcumin_4h_R1 2 TEELIESPKLESSEGEIIQTVDR 23 1 F8VXG7;Q99590-2;Q99590;A0A0A0MTP7 F8VXG7 SCAF11 Protein SCAF11 1 0 TEELIES(0.001)PKLES(0.272)S(0.718)EGEIIQT(0.009)VDR;TEELIESPKLES(0.171)S(0.82)EGEIIQT(0.009)VDR ; 100.27 2.66E-05 21625200 2654.9 2213.5 2365.9 2286.3 2057.4 2444.7 1784.73 2101.6 2690.5 2398.4 TRUE FALSE FALSE 2444.761864 2404.825077 2453.582335 2276.839896 2032.866849 1937.641663 1834.80472 2742.368165 2395.358881 2481.744221 0.98509824 0.969006014 0.988652382 0.917435357 0.819128269 0.780758003 0.739320638 1.10501644 0.965191683 1 11.27713872 -6.043522598 3.049945083 0.990298275 0.84712628 0.267038175 0.092111368 0.209706118 3.908301027 0.012998396 0.023460375 9.05E-07 6.043522598 -0.143171995 TEEPDRDER ddPTM_HeLa_Curcumin_4h_R1 1 TEEPDRDER 9 1 O95232;J3KPP4;H0YA81 O95232 LUC7L3 Luc7-like protein 3 0 0 109.48 0.0080358 5298500 3125.6 3215.6 2603.2 2476.7 2729.5 3264.8 2180 2846.4 2257 2922.1 FALSE FALSE TRUE 2878.205462 3493.542136 2699.676882 2466.452072 2696.952495 2587.643678 2241.164933 3714.254257 2009.412747 3023.642757 0.951899974 1.155408365 0.89285577 0.815722051 0.891954742 0.855803375 0.741213534 1.228403801 0.664566851 1 11.56207198 -6.583250143 24.9995842 0.991635506 0.88983841 0 0.166977935 107.4091976 44477.09927 0.019049468 0.026939813 2.61E-07 6.583250143 -0.101797096 TEERAELAESR ddPTM_HeLa_Curcumin_4h_R1 1 TEERAELAESR 11 1 A0A087WWU8;P06753-2;P06753-3;P06753-6;J3KN67;A0A494C0P6;A0A2R2Y2Q3 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 0 82.831 0.018157 989460 834.42 554.79 575.36 639.78 486.84 810.15 613.53 715.01 1290.3 828.6 FALSE FALSE TRUE 768.3747765 602.7435755 596.6833477 637.1327599 481.034751 642.1157577 630.7440006 933.0132575 1148.757318 857.3937883 0.896174881 0.702995034 0.695926838 0.743104007 0.561042962 0.748915803 0.735652636 1.088196894 1.339824633 1 9.743814155 -7.506582053 2.172823978 0.961668402 0.742804624 0.373149683 0.174335292 0.229640379 2.154372792 0.023899686 0.025918559 3.11E-08 7.506582053 -0.218863778 TEES(ph)PASDEAGEKEAK ddPTM_HeLa_Curcumin_4h_R1 3 TEESPASDEAGEKEAK 16 1 P05114;A6NL93;A6NEL0 P05114 HMGN1 Non-histone chromosomal protein HMG-14 1 0 T(0.069)EES(0.821)PAS(0.109)DEAGEKEAK;T(0.198)EES(0.792)PAS(0.01)DEAGEKEAK;T(0.007)EES(0.845)PAS(0.148)DEAGEKEAK ;; 99.371 0.0013429 63003000 10589.1 8367.3 9536.9 9595.1 11108.1 11929.3 11009.3 9585 10403 9207.6 TRUE FALSE FALSE 9750.961561 9090.532128 9890.345904 9555.398019 10975.64316 9455.028709 11318.19133 12507.42238 9261.816927 9527.563415 1.023447563 0.954129795 1.038077153 1.002921482 1.151988466 0.992386857 1.187941852 1.312761913 0.972107613 1 13.21789159 -1.000000092 0.592088515 1.007976688 20.01639276 0.7765706 0.051946021 44.63586063 0.326634092 0.008125626 1098.5602 0.099999979 1.000000092 19.00841607 TEESPAS(ph)DEAGEK ddPTM_HeLa_Curcumin_4h_R1 1 TEESPASDEAGEK 13 0 P05114;A6NL93;A6NEL0 P05114 HMGN1 Non-histone chromosomal protein HMG-14 1 0 TEES(0.006)PAS(0.994)DEAGEK 144.88 0.00077869 16311000 2389.7 1865.9 2374.9 2082.4 3010.4 2648.5 2434.6 2020 1557.6 1689.4 TRUE FALSE FALSE 2200.552723 2027.180082 2462.915883 2073.783581 2974.502946 2099.171245 2502.908324 2635.888701 1386.735177 1748.106524 1.258820726 1.159643336 1.40890492 1.186302752 1.70155703 1.200825703 1.431782497 1.507853592 0.793278417 1 10.77157739 -11.69214521 0.082401619 6.43E-12 1.805084634 0.601851983 0.156134052 57.50430105 0.543450705 12.70075852 2.598781485 2.03E-12 11.69214521 1.805084634 TEESPAS(ph)DEAGEKEAK ddPTM_HeLa_Curcumin_4h_R1 1 TEESPASDEAGEKEAK 16 1 P05114;A6NL93;A6NEL0 P05114 HMGN1 Non-histone chromosomal protein HMG-14 1 0 T(0.091)EES(0.349)PAS(0.56)DEAGEKEAK 82.651 0.0047233 16717000 2757.6 2356 2563.3 3641.5 3663.9 3517.5 2719.8 3126.6 3141.6 2705.5 TRUE FALSE FALSE 2539.33305 2559.642142 2658.298153 3626.432438 3620.210385 2787.93085 2796.110268 4079.885947 2796.97434 2799.515924 0.907061478 0.914315979 0.949556361 1.295378393 1.293155847 0.995861758 0.998783484 1.457354078 0.999092135 1 11.45096167 -6.278572964 23.87701461 0.950750884 1.189411203 0.476182618 0.132508774 318.3073401 443586.0119 0.02013428 0.030811492 5.27E-07 6.278572964 0.238660319 TEESPASDEAGEKEAKS(ph)D ddPTM_HeLa_Curcumin_4h_R1 3 TEESPASDEAGEKEAKSD 18 2 P05114;A6NL93;A6NEL0 P05114 HMGN1 Non-histone chromosomal protein HMG-14 1 0 TEESPASDEAGEKEAKS(1)D;TEESPASDEAGEKEAKS(1)D;TEESPASDEAGEKEAKS(1)D ;; 99.603 0.0011155 285075000 9248.3 8228.4 9038.2 9531.2 11306.6 10739.7 10307.9 8977.2 9628.1 9274.7 TRUE FALSE FALSE 8516.287296 8939.626231 9373.163643 9491.76242 11171.77618 8512.165159 10597.11193 11714.30695 8571.921518 9596.995135 0.887391019 0.931502632 0.976676919 0.989034827 1.164091054 0.886961496 1.104211452 1.220622371 0.893188065 1 13.22836705 -5.954390801 6.74713952 0.947593347 1.080218585 0.414786182 0.086682599 0.179207089 19.93956685 0.013028965 0.023663173 1.11E-06 5.954390801 0.132625238 TEFLDLDNSPLSPPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 TEFLDLDNSPLSPPSPR 17 0 Q8NCF5 Q8NCF5 NFATC2IP NFATC2-interacting protein 1 0 TEFLDLDNSPLSPPS(1)PR;TEFLDLDNSPLSPPS(1)PR;TEFLDLDNSPLSPPS(1)PR ;; 222.93 4.34E-16 50454600 10121.5 8373.4 9804.7 9232.3 10428.6 11830.6 9270.5 9744.1 9141.1 9544.9 TRUE FALSE FALSE 9320.372595 9097.159385 10168.07081 9194.099189 10304.24576 9376.800202 9530.60528 12715.03123 8138.3442 9876.584565 0.943683774 0.921083531 1.029512858 0.930898645 1.043300514 0.949397045 0.964969744 1.287391522 0.8240039 1 13.26979651 -4.260554289 24.96383305 0.972966456 1.287391622 0.722108392 0.060830511 18.76737341 529243.0365 0.005173432 0.041963774 5.49E-05 4.260554289 0.314425166 TEFLHSQNS(ph)LSPR ddPTM_HeLa_Curcumin_4h_R1 1 TEFLHSQNSLSPR 13 0 F6RY50;Q96FS4 F6RY50 SIPA1 Signal-induced proliferation-associated protein 1 1 0 TEFLHS(0.001)QNS(0.983)LS(0.016)PR 198.81 1.50E-06 9683100 903.72 785.06 898.3 860.71 1089.4 922.37 737.1 514.54 1034.6 645.3 TRUE FALSE FALSE 832.1896084 852.9170882 931.5917882 857.1486101 1076.409617 731.0600647 757.7810422 671.4208773 921.1069684 667.724127 1.246307531 1.277349513 1.39517467 1.283686743 1.612057395 1.094853451 1.134871441 1.005536344 1.379472347 1 9.38310836 -8.906315119 0.808245258 1.004277783 1.264248849 0 0.196055438 0.656890283 0.80956682 0.098031106 0.03378187 1.24E-09 8.906315119 0.259971066 TEFLHSQNSLS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 TEFLHSQNSLSPR 13 0 F6RY50;Q96FS4 F6RY50 SIPA1 Signal-induced proliferation-associated protein 1 1 0 TEFLHSQNS(0.033)LS(0.967)PR 89.466 0.006126 29993000 3142.2 2725.2 2620.1 2376.6 3105.4 3864.1 2440.7 2679.2 3359.5 2277.5 TRUE FALSE FALSE 2893.491554 2960.754145 2717.203211 2366.766259 3068.370133 3062.642103 2509.179473 3496.075746 2990.971255 2356.642955 1.227802263 1.256343961 1.152997404 1.004295646 1.302008913 1.299578324 1.064726189 1.48349827 1.26916606 1 11.20251748 -13.46265154 0.199050451 3.95E-13 1.260763893 0 0.150017529 44.46380838 0.550169425 17.29096253 0.125169913 3.45E-14 13.46265154 1.260763893 TEFSPAAFEQEQLGS(ph)PQVR ddPTM_HeLa_Curcumin_4h_R1 1 TEFSPAAFEQEQLGSPQVR 19 0 Q92585 Q92585 MAML1 Mastermind-like protein 1 1 0 TEFSPAAFEQEQLGS(1)PQVR 126.04 0.00014961 2588800 963.21 874.35 960.98 866.47 924.88 991.42 833.67 731.29 1213.5 931.45 TRUE FALSE FALSE 886.9709121 949.924918 996.5947642 862.8847767 913.8514101 785.7883164 857.0605365 954.2569546 1080.382086 963.8178182 0.920268224 0.985585554 1.034007408 0.895277884 0.948157829 0.815287186 0.889234999 0.990080217 1.120940146 1 9.912616662 -6.212980355 24.98880014 0.968390768 0.903710773 0.26618343 0.069801189 424.8605103 219087.2218 0.008170882 0.013549855 6.12E-07 6.212980355 -0.064679995 TEGAEAT(ph)PGAQK ddPTM_HeLa_Curcumin_4h_R1 3 TEGAEATPGAQK 12 0 X6RHM1;Q16666-3;Q16666-2;Q16666;H3BM18 X6RHM1 IFI16 Gamma-interferon-inducible protein 16 1 0 TEGAEAT(1)PGAQK;TEGAEAT(1)PGAQK;T(0.002)EGAEAT(0.998)PGAQK ;; 165.51 0.00034487 14106000 7650.2 7293 7827.4 9197.8 8748.4 15464 16064 4986.5 7089.4 6459.1 TRUE FALSE FALSE 7044.678598 7923.374423 8117.49033 9159.741941 8644.081044 12256.59208 16514.71261 6506.860895 6311.710557 6683.553244 1.054031941 1.185503299 1.214547118 1.370489859 1.293336153 1.833843711 2.470948013 0.973563112 0.944364521 1 12.70639959 -5.795045811 1.066879002 1.03943789 1.812921664 0.379645844 0.356914233 0.338092273 0.748928458 0.054460834 0.158391589 1.60E-06 5.795045811 0.773483774 TEGAEATPGAQK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 TEGAEATPGAQKR 13 1 X6RHM1;Q16666-3;Q16666-2;Q16666;H3BM18 X6RHM1 IFI16 Gamma-interferon-inducible protein 16 0 1 ; TEGAEATPGAQK(1)R;TEGAEATPGAQK(1)R 149.94 8.13E-05 1684040 1153.65 1135.23 1055.79 1315.33 979.48 1426.29 1168.54 942.79 1468.89 1142.95 FALSE TRUE FALSE 1062.337385 1233.354223 1094.918506 1309.887513 967.8003407 1130.461376 1201.326087 1230.242331 1307.756442 1182.667427 0.898255385 1.042858029 0.925804229 1.107570465 0.818319942 0.95585737 1.01577676 1.040226781 1.105768546 1 10.20782872 -7.269301581 24.91120492 0.951953935 0.982406519 0 0.091357064 1915.08341 6067889.608 0.013404748 0.01549723 5.38E-08 7.269301581 0.030452585 TEGKPAEVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 TEGKPAEVKK 10 2 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;P27816-4;B5MEG9;H7C4C5;H0Y2V1 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 0 1 ; TEGKPAEVK(1)K;TEGKPAEVK(1)K 110.84 0.0011459 17153400 9109.2 9565.5 8637.6 7864.8 8218.8 12410.3 7860.3 6852.9 9692.3 9049.7 FALSE TRUE FALSE 8388.197208 10392.2992 8957.717054 7832.257541 8120.796178 9836.263887 8080.838863 8942.317663 8629.078939 9364.176401 0.895775223 1.10979319 0.956594224 0.83640645 0.867219479 1.050414203 0.862952439 0.954949723 0.921498973 1 13.1929364 -6.493702793 24.42956478 0.964755265 0.914470682 0.131254039 0.077464551 1105.774942 925886.1895 0.01235542 0.018849096 3.21E-07 6.493702793 -0.050284584 TEGSS(ph)PPDSK ddPTM_HeLa_Curcumin_4h_R1 2 TEGSSPPDSK 10 0 A0A1P0AZG4;Q96JN0-3 A0A1P0AZG4 1 0 TEGS(0.348)S(0.648)PPDS(0.003)K;T(0.001)EGS(0.032)S(0.956)PPDS(0.011)K ; 116.84 0.0052059 0 6758 10169.3 7975.6 7327 7382.9 7176.4 4627.3 2538.48 6793.6 7075.7 TRUE FALSE FALSE 6223.097169 11048.28898 8271.182752 7296.682815 7294.863739 5687.933745 4757.129584 3312.450866 6048.359077 7321.580048 0.849966418 1.509003372 1.129699149 0.996599473 0.996351019 0.776872438 0.649740842 0.452422953 0.826100246 1 12.83793931 -4.776845809 1.468984965 0.997936165 0.448083965 0.541650094 0.18352661 0.370419575 1.283655916 0.029013238 0.224547062 1.67E-05 4.776845809 -0.5498522 TEGT(ph)PPPPGQPAK ddPTM_HeLa_Curcumin_4h_R1 1 TEGTPPPPGQPAK 13 0 A0A494C150;F8VWT9;J3KPF0;Q9Y4D8-2;Q9Y4D8-4;Q9Y4D8 A0A494C150 HECTD4 Probable E3 ubiquitin-protein ligase HECTD4 1 0 T(0.014)EGT(0.986)PPPPGQPAK 169.58 0.00055994 6650000 5600.4 4208.6 4305.4 4602 4367.6 5018.1 3269.1 4589.3 4809.7 4593.2 TRUE FALSE FALSE 5157.12243 4572.372631 4464.961911 4582.958143 4315.519223 3977.289494 3360.822148 5988.556443 4282.087943 4752.813358 1.085067315 0.962034965 0.939435567 0.964262174 0.907992571 0.836828462 0.707122686 1.260002443 0.900958574 1 12.21456603 -7.033078248 3.593976691 1.040060077 0.921815409 0 0.139001308 0.330381432 8.927193529 0.020862669 0.026573511 9.27E-08 7.033078248 -0.118244668 TEHQVPSSVSSPDDAMVS(ph)PLKPAPK ddPTM_HeLa_Curcumin_4h_R1 1 TEHQVPSSVSSPDDAMVSPLKPAPK 25 1 A0A0X1KG75;A0A590PXD8;A0A0D9SG04;Q53SF7;Q53SF7-3;Q53SF7-2 A0A0X1KG75 COBLL1 Cordon-bleu protein-like 1 1 0 TEHQVPS(0.017)S(0.017)VS(0.014)S(0.014)PDDAMVS(0.939)PLKPAPK 69.133 0.00027152 8117900 1749.4 1669.3 1660.7 1437.2 1675.6 2821.3 1790.6 1420.1 2181.3 1591.1 TRUE FALSE FALSE 1610.933144 1813.586854 1722.247003 1431.253247 1655.619564 2236.130577 1840.839417 1853.081953 1942.016847 1646.390607 0.978463517 1.101553208 1.046074362 0.869327875 1.00560557 1.358201734 1.118106122 1.125542107 1.179560209 1 10.68509094 -5.396856145 9.809066258 0.993749127 1.192121719 0.357784329 0.101065297 0.20087355 15.04730768 0.011251712 0.025179059 4.01E-06 5.396856145 0.198372591 TEIIS(ph)EVNHLDNDK ddPTM_HeLa_Curcumin_4h_R1 1 TEIISEVNHLDNDK 14 0 Q562F6-2;Q562F6 Q562F6-2 SGOL2 Shugoshin-like 2 1 0 TEIIS(1)EVNHLDNDK 90.108 0.0098765 9718100 914.85 815.06 857.92 826.46 951.33 868.2 587.66 513.37 902.17 794.14 TRUE FALSE FALSE 842.4386572 885.5101546 889.7152699 823.0403275 939.9860111 688.1255334 604.148158 669.8941497 803.2042081 821.7363059 1.025193424 1.077608654 1.082726008 1.00158691 1.143902252 0.837404321 0.73520928 0.815217905 0.977447634 1 9.682531699 -5.096554936 5.49879999 1.02916194 0.777402151 0.832408885 0.051162984 0.060798598 2.749483315 0.006904233 0.018177994 8.01E-06 5.096554936 -0.25175979 TEIKEEEDQPSTSATQS(ph)SPAPGQSK ddPTM_HeLa_Curcumin_4h_R1 1 TEIKEEEDQPSTSATQSSPAPGQSK 25 1 A0A669KB12;Q09472 A0A669KB12 EP300 Histone acetyltransferase p300 1 0 TEIKEEEDQPS(0.001)T(0.002)S(0.009)AT(0.1)QS(0.44)S(0.44)PAPGQS(0.007)K 84.948 4.08E-05 92142000 6129.8 4642.9 5314.8 6192.6 7288.9 6907.2 5788.8 4077.4 5175.9 5027.5 TRUE FALSE FALSE 5644.619862 5044.211588 5511.771163 6166.976662 7201.984628 5474.56886 5951.218148 5320.58049 4608.116719 5202.205251 1.085043667 0.969629483 1.05950667 1.185454315 1.384409934 1.052355414 1.143979882 1.022754819 0.885800636 1 12.34490761 -6.346011373 5.17580025 1.035310824 1.163496062 0.33338425 0.106030189 0.221451021 10.09793181 0.014904677 0.022998634 4.51E-07 6.346011373 0.128185238 RIS(ph)QVS(ph)SGETEYNPTEAR ddPTM_HeLa_Curcumin_4h_R1 1 RISQVSSGETEYNPTEAR 18 1 H7C3Y7;H0Y764;A0A494C1V1;Q6ZNJ1-2;Q6ZNJ1-3;Q6ZNJ1 H7C3Y7 NBEAL2 Neurobeachin-like protein 2 2 0 RIS(1)QVS(0.798)S(0.197)GET(0.006)EYNPTEAR 107.63 0.0016621 0 1110 789.43 1048.4 1037.6 1140.6 1487.1 1363.4 1941.3 1144.1 933.99 TRUE FALSE FALSE 1022.142329 857.6648116 1087.254626 1033.306686 1126.99909 1178.658697 1401.653335 2533.193433 1018.595092 966.446083 1.057629957 0.887441966 1.12500288 1.069181928 1.166127226 1.219580396 1.450317156 2.62114305 1.053959564 1 9.916545438 -1.702614937 0.909985634 1.028402375 199.9999996 0.977760126 0.070637521 20.46750023 0.174155216 0.010789079 8293.045408 0.019832847 1.702614937 198.9715972 up TEKEPDATPPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 TEKEPDATPPSPR 13 1 A0A494C0S2;A0A090HNM7;A0A1W2PS85;R4GMW8;P28715 A0A494C0S2 ERCC5-201;BIVM-ERCC5;ERCC5 DNA repair protein complementing XP-G cells 1 0 TEKEPDATPPS(1)PR 104.16 0.0023166 34765000 4075.4 2986.2 3739 3990.1 4072 5316.4 4258.9 4054.1 4313 4544.7 TRUE FALSE FALSE 3752.82779 3244.313822 3877.570629 3973.590023 4023.44406 4213.718712 4378.393272 5290.176427 3839.874691 4702.627987 0.798027784 0.689893785 0.824553981 0.844972223 0.855573537 0.896034882 0.931052442 1.124940447 0.816538051 1 12.19925149 -4.145191625 1.759216326 0.872857375 1.266029045 0.518205531 0.078839417 1.122508885 2.695095874 0.014898547 0.804889159 7.16E-05 4.145191625 0.39317167 TELADK(ac)VTK ddPTM_HeLa_Curcumin_4h_R1 2 TELADKVTK 9 1 P35579 P35579 MYH9 Myosin-9 0 1 ; TELADK(1)VTK;TELADK(1)VTK 159.4 3.10E-08 6216000 2807.4 3456.7 2580.8 2398.75 4645 6093.7 4445.6 4398.6 8083.1 3314.4 FALSE TRUE FALSE 2585.191328 3755.481745 2676.446718 2388.824608 4589.611409 4829.79793 4570.331571 5739.712891 7196.404153 3429.575153 0.753793462 1.09502827 0.780401828 0.696536597 1.338244886 1.408278785 1.332623245 1.673592977 2.098336917 1 11.74381415 -5.649777195 5.440422372 0.878926187 1.443536277 0.062545695 0.409400083 0.074238322 3.272243373 0.021578003 0.043630291 2.24E-06 5.649777195 0.56461009 ISFPGSSES(ph)PLSSK ddPTM_HeLa_Curcumin_4h_R1 1 ISFPGSSESPLSSK 14 0 Q15911;Q15911-2 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 0 ISFPGS(0.075)S(0.04)ES(0.881)PLS(0.003)SK 235.93 3.69E-21 39728000 3834.9 2615.9 2659.5 3164 3236.8 3049.4 2958.2 906.42 3551.1 2607.8 TRUE FALSE FALSE 3531.363618 2842.00674 2758.06341 3150.908206 3198.203274 2416.920066 3041.19913 1182.783285 3161.553214 2698.420856 1.308677855 1.053211078 1.022102762 1.167685982 1.185212924 0.895679434 1.127029212 0.438324245 1.171630885 1 11.39789966 -4.084267112 2.227873936 1.125000819 9.77E-15 0.744262647 0.115243386 0.599596572 2.13497858 0.019574101 1.58189647 8.24E-05 4.084267112 -1.125000819 down TELGSQT(ph)PESSR ddPTM_HeLa_Curcumin_4h_R1 3 TELGSQTPESSR 12 0 H0YID1;F8VUX5;H0YIQ8;F8VXI8;F8VX10;Q9H9L4-4;Q9H9L4 H0YID1 KANSL2 KAT8 regulatory NSL complex subunit 2 1 0 TELGS(0.001)QT(0.976)PES(0.022)SR;TELGS(0.005)QT(0.995)PESSR;T(0.001)ELGS(0.002)QT(0.997)PESSR ;; 168 1.44E-08 17455100 5009.6 4193.1 4660.1 4708.15 4670.1 5937.3 4306.1 2261.25 5574.1 4316.15 TRUE FALSE FALSE 4613.084874 4555.53288 4832.807405 4688.668923 4614.412108 4705.837053 4426.917577 2950.694715 4962.635176 4466.135891 1.032902936 1.02001663 1.082100394 1.049826749 1.033200113 1.053670817 0.991218737 0.660681804 1.111169767 1 12.12481143 -4.263078525 3.963855773 1.026653129 0.627609447 0.913123131 0.035140797 0.038202616 1.228636341 0.00376787 0.043669363 5.46E-05 4.263078525 -0.399043681 TELIQK(ac)AK ddPTM_HeLa_Curcumin_4h_R1 1 TELIQKAK 8 1 P27348;E9PG15 P27348 YWHAQ 14-3-3 protein theta 0 1 TELIQK(1)AK 99.136 0.013957 2190700 2097.7 2140 1808.2 1524.6 1792.8 2022.4 1908.8 2001 2436 1726.2 FALSE TRUE FALSE 1931.664832 2324.972064 1875.213483 1518.291609 1771.422031 1602.931443 1962.355791 2611.095689 2168.776895 1786.185322 1.081447041 1.301641009 1.049842623 0.850019083 0.991734737 0.89740489 1.098629446 1.461827985 1.214194781 1 10.80266606 -4.281364702 3.938030687 1.033544723 1.493883312 0.479287769 0.127553338 0.130544237 4.072620086 0.016388125 0.165758128 5.23E-05 4.281364702 0.460338589 TELPS(ph)PESAQSPSPSGDVR ddPTM_HeLa_Curcumin_4h_R1 1 TELPSPESAQSPSPSGDVR 19 0 O15021;H7C1I9;O15021-2;O15021-3;O15021-6 O15021 MAST4 Microtubule-associated serine/threonine-protein kinase 4 1 0 T(0.045)ELPS(0.953)PESAQS(0.001)PS(0.001)PSGDVR 124.98 0.00016472 8812700 1329.2 1014.5 972.63 1133.6 1482.2 1356.9 1103 1952.5 1385.7 1222.6 TRUE FALSE FALSE 1223.992417 1102.188859 1008.676523 1128.909464 1464.525733 1075.463645 1133.947211 2547.808262 1233.692177 1265.085259 0.96751773 0.871236821 0.797319008 0.892358405 1.157649828 0.850111593 0.896340546 2.013941941 0.975185007 1 10.3050189 -4.259466761 24.99734597 0.956317382 2.0139423 0.917130867 0.097165436 35.58032779 450845.6709 0.013635967 0.119043049 5.50E-05 4.259466761 1.057624918 TELSQSDMFDQR ddPTM_HeLa_Curcumin_4h_R1 1 TELSQSDMFDQR 12 0 B7Z7P8;P62495-2;P62495 B7Z7P8 ETF1 Eukaryotic peptide chain release factor subunit 1 0 0 183.67 0.00031642 19708000 1490.3 1296.8 1642.4 1040.7 1402.4 1795.2 1255.6 1272.2 1486.6 1266.6 FALSE FALSE TRUE 1372.341182 1408.889614 1703.268789 1036.393859 1385.677296 1422.855284 1290.828757 1660.087924 1323.523699 1310.614256 1.047097707 1.074984197 1.299595805 0.790769561 1.057273175 1.085640018 0.984903644 1.266648761 1.009849918 1 10.35602741 TEMDKSPFNS(ph)PSPQDSPR ddPTM_HeLa_Curcumin_4h_R1 1 TEMDKSPFNSPSPQDSPR 18 1 A0A286YEX4;P08651-4;P08651-5;P08651-3;P08651-6;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 0 TEMDKS(0.006)PFNS(0.434)PS(0.294)PQDS(0.266)PR 66.448 0.0091131 0 3458.8 2785 3033 3292.9 2522.6 3728.4 3145.3 2210.5 3635.3 2769.2 TRUE FALSE FALSE 3185.03233 3025.72299 3145.405648 3279.274852 2492.519643 2955.087812 3233.548653 2884.471274 3236.516685 2865.429494 1.111537498 1.055940478 1.097708268 1.144426991 0.869859003 1.031289661 1.128469104 1.006645349 1.129504911 1 11.48453568 TEMEDLMSSK ddPTM_HeLa_Curcumin_4h_R1 2 TEMEDLMSSK 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ; ; 159.83 1.37E-23 0 824.87 1037.44 1202.03 725.95 940.16 1186.12 876.4 1001.91 873.59 816.31 FALSE FALSE TRUE 759.5806691 1127.111691 1246.578289 722.9462113 928.949206 940.1053417 900.9894253 1307.387747 777.7593626 844.6767117 0.899256081 1.334370506 1.475805207 0.855885099 1.099768933 1.112976514 1.066667771 1.547796605 0.920777561 1 9.722255465 -1 0.246052733 0.960288168 3.368846163 0.207920197 0.204920791 54.04140678 0.671458851 0.122446603 54.21393715 0.1 1 2.408557995 TEMQDNTYPEILR ddPTM_HeLa_Curcumin_4h_R1 1 TEMQDNTYPEILR 13 0 O43143 O43143 DHX15 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 0 0 178.71 9.15E-15 0 868.02 853.7 997.19 1054 829 1071.4 1010.4 885.34 941.69 848.77 FALSE FALSE TRUE 799.3153011 927.490024 1034.146739 1049.638827 819.1147164 849.1795628 1038.749105 1155.27609 838.388963 878.2646943 0.910107518 1.056048399 1.177488683 1.195128113 0.932651309 0.96688341 1.182728978 1.315407642 0.954597137 1 9.778511999 -7.049730144 4.996771367 0.958073731 1.117886907 0.343066951 0.106794674 0.195748298 10.93249967 0.018967825 0.02368373 8.92E-08 7.049730144 0.159813176 TENNDHINLK ddPTM_HeLa_Curcumin_4h_R1 1 TENNDHINLK 10 0 P61956-2;P61956 P61956-2 SUMO2 Small ubiquitin-related modifier 2 0 0 83.862 0.0095429 7411900 9585.7 7815.5 7262.4 7803.2 8161.5 9549.1 7218.4 5091.3 8930.8 7620.7 FALSE FALSE TRUE 8826.98173 8491.036995 7531.550933 7770.912426 8064.179443 7568.509019 7420.928877 6643.613933 7951.113584 7885.518758 1.119391381 1.076788637 0.955111663 0.985466228 1.022656808 0.959798493 0.941083156 0.842508164 1.008318391 1 12.94498995 -3.628370458 0.490461102 1.053689401 0.551613646 0.614893831 0.044775967 4.013985327 0.416947825 0.011789732 1.333040923 0.000235304 3.628370458 -0.502075755 TEPAAEAEAASGPS(ph)ESPS(ph)PPAAEELPGSHAEPPVPAQGEAPGEQAR ddPTM_HeLa_Curcumin_4h_R1 1 TEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR 46 0 P55884-2;P55884 P55884-2 EIF3B Eukaryotic translation initiation factor 3 subunit B 2 0 TEPAAEAEAAS(0.02)GPS(0.573)ES(0.516)PS(0.835)PPAAEELPGS(0.056)HAEPPVPAQGEAPGEQAR 90.177 3.52E-13 7193600 2457.9 2210.8 1895.6 1938.7 2051.1 1882.2 1687.8 1628.6 2543.8 2221.2 TRUE FALSE FALSE 2263.354621 2401.891701 1965.852604 1930.678173 2026.641972 1491.810503 1735.155126 2125.152643 2264.751504 2298.386535 0.984758041 1.045033838 0.855318535 0.840014568 0.881767249 0.649068588 0.754944871 0.924628043 0.985365808 1 11.16640573 -6.612946833 4.025562721 0.996377924 0.805150676 0.620302984 0.071707165 0.110095636 3.395403506 0.011340425 0.016311574 2.44E-07 6.612946833 -0.191227248 TEPAAEAEAASGPS(ph)ESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR ddPTM_HeLa_Curcumin_4h_R1 1 TEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR 46 0 P55884-2;P55884 P55884-2 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 0 TEPAAEAEAAS(0.004)GPS(0.33)ES(0.33)PS(0.33)PPAAEELPGS(0.005)HAEPPVPAQGEAPGEQAR 94.437 4.45E-17 66581000 2345.4 2188.2 1877.2 2138.7 1545.2 1856 1352.5 1723.5 2027.2 1876.3 TRUE FALSE FALSE 2159.759115 2377.338258 1946.770683 2129.850626 1526.774499 1471.044679 1390.44751 2248.987216 1804.821232 1941.501285 1.112417041 1.224484514 1.002714084 1.097012215 0.786388611 0.757684113 0.716171305 1.158375342 0.929600843 1 10.92295695 -5.76472014 24.99878359 1.06715288 0.837836666 0.356727232 0.134868445 60.2936607 459431.5514 0.0183782 0.034333075 1.72E-06 5.76472014 -0.229316214 TEPAAEAEAASGPSES(ph)PS(ph)PPAAEELPGSHAEPPVPAQGEAPGEQAR ddPTM_HeLa_Curcumin_4h_R1 1 TEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR 46 0 P55884-2;P55884 P55884-2 EIF3B Eukaryotic translation initiation factor 3 subunit B 2 0 TEPAAEAEAAS(0.034)GPS(0.25)ES(0.771)PS(0.912)PPAAEELPGS(0.033)HAEPPVPAQGEAPGEQAR 101.92 5.91E-18 7292500 889.37 645.34 701.13 892.67 577.55 901.31 789.78 590.47 730.87 834.93 TRUE FALSE FALSE 818.975426 701.120314 727.1144946 888.9763681 570.6630935 714.3681461 811.9391012 770.5015848 650.6953895 863.9437554 0.947949934 0.811534674 0.84162249 1.028974818 0.660532691 0.826868811 0.93980551 0.891842299 0.753168694 1 9.754793583 -7.450215577 3.775215961 0.978399052 0.857910675 0 0.11445915 0.227464161 5.970313743 0.015676071 0.017500339 3.55E-08 7.450215577 -0.120488378 TEPAAEAEAASGPSES(ph)PSPPAAEELPGSHAEPPVPAQGEAPGEQAR ddPTM_HeLa_Curcumin_4h_R1 2 TEPAAEAEAASGPSESPSPPAAEELPGSHAEPPVPAQGEAPGEQAR 46 0 P55884-2;P55884 P55884-2 EIF3B Eukaryotic translation initiation factor 3 subunit B 1 0 TEPAAEAEAAS(0.005)GPS(0.185)ES(0.637)PS(0.162)PPAAEELPGS(0.012)HAEPPVPAQGEAPGEQAR;TEPAAEAEAAS(0.069)GPS(0.276)ES(0.295)PS(0.295)PPAAEELPGS(0.065)HAEPPVPAQGEAPGEQAR ; 96.411 3.40E-17 14210600 2450.3 1636.37 1450.51 1644.53 1912.35 2407.4 1798.97 1614.21 2261.5 2132.8 TRUE FALSE FALSE 2256.356169 1777.810531 1504.267177 1637.725371 1889.546475 1908.078103 1849.444257 2106.375198 2013.419108 2206.914641 1.022403009 0.805563794 0.681615477 0.742088226 0.856193729 0.864590804 0.83802256 0.954443438 0.912323055 1 11.10781511 -7.261151134 24.9957485 1.010579201 0.815771722 0.461796248 0.075617153 12.7279723 1103747.095 0.012305087 0.01458249 5.48E-08 7.261151134 -0.194807479 TEPLNSSETTATTGDGALDTFTGSVITSSGYS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 TEPLNSSETTATTGDGALDTFTGSVITSSGYSPR 34 0 E9PLN6;F2Z2Y1;O95677-3;O95677-2;O95677-4;O95677 E9PLN6 EYA4 Eyes absent homolog;Eyes absent homolog 4 1 0 TEPLNSSETTATTGDGALDTFTGSVIT(0.003)S(0.006)S(0.032)GYS(0.959)PR 108.5 2.04E-14 4884100 1386.6 961.81 1060.1 1246.7 996.49 1119.4 779.25 450.9 1085.2 1069.6 TRUE FALSE FALSE 1276.849147 1044.944571 1099.388239 1241.541486 984.6075076 887.2238218 801.1136578 588.3773343 966.156275 1106.76852 1.15367317 0.944140126 0.993331684 1.121771593 0.889623701 0.801634493 0.723831265 0.531617338 0.872952435 1 10.1121378 -4.688781699 0.75965718 1.06543815 0.401995117 0.733920471 0.09101743 0.46910671 0.274142994 0.013380794 0.232134086 2.05E-05 4.688781699 -0.663443033 TEPS(ph)SPLSDPSDIIR ddPTM_HeLa_Curcumin_4h_R1 1 TEPSSPLSDPSDIIR 15 0 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 0 TEPS(0.497)S(0.497)PLS(0.005)DPSDIIR 177.21 7.77E-05 29837000 3357.1 2702 3175.2 3115.9 3396.5 3831.7 3024.8 2548.2 3270.2 2394.2 TRUE FALSE FALSE 3091.381993 2935.54884 3292.875705 3103.007231 3355.998956 3036.962228 3109.667747 3325.13445 2911.467242 2477.398272 1.24783408 1.184932142 1.329166869 1.252526599 1.354646523 1.225867581 1.255215111 1.342188088 1.175211622 1 11.2746101 -9.313891477 0.394216098 0.904309252 1.295477929 0.46360155 0.072099334 0.68106192 0.13481275 0.113272364 0.016001383 4.85E-10 9.313891477 0.391168676 TEPSS(ph)PLSDPSDIIR ddPTM_HeLa_Curcumin_4h_R1 1 TEPSSPLSDPSDIIR 15 0 Q9ULJ3;Q9ULJ3-2 Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 1 0 TEPS(0.029)S(0.971)PLSDPSDIIR 188.63 3.14E-06 33445000 3329.2 3410.7 3739.3 3679.3 3475.2 4009.2 3125.8 2745.9 3158.5 3111.5 TRUE FALSE FALSE 3065.690307 3705.50571 3877.881747 3664.076031 3433.76051 3177.646727 3213.501535 3583.112269 2812.020452 3219.624393 0.952188806 1.150912423 1.204451599 1.138044562 1.066509658 0.986961937 0.998098269 1.112897603 0.873400157 1 11.65267668 -7.272395425 24.93829594 0.97742249 1.091065161 0.466476487 0.071534837 570.9639998 1299633.877 0.012319105 0.014165255 5.34E-08 7.272395425 0.113642671 TEPTS(ph)PTPSAFK ddPTM_HeLa_Curcumin_4h_R1 1 TEPTSPTPSAFK 12 0 Q86XN7-2;Q86XN7 Q86XN7-2 PROSER1 Proline and serine-rich protein 1 1 0 T(0.001)EPT(0.01)S(0.987)PT(0.002)PSAFK 92.792 0.013331 21767000 3894.2 3310.3 3855.5 3682.7 3789.8 4109.3 3490 3444 3804 3115.1 TRUE FALSE FALSE 3585.969961 3596.427582 3998.388222 3667.461963 3744.60911 3256.984859 3587.920007 4494.059746 3386.710717 3223.349493 1.11249803 1.115742363 1.240445143 1.137779807 1.161713652 1.010434911 1.113103005 1.394220439 1.050680581 1 11.65434491 -13.52287875 0.080338087 0.443508568 1.324671648 0.300539097 0.092082748 153.5600334 0.946500428 15.14776489 1.662793229 3.00E-14 13.52287875 0.881163081 TEQELPRPQS(ph)PSDLDS(ph)LDGR ddPTM_HeLa_Curcumin_4h_R1 1 TEQELPRPQSPSDLDSLDGR 20 1 P54259 P54259 ATN1 Atrophin-1 2 0 TEQELPRPQS(0.946)PS(0.174)DLDS(0.88)LDGR 90.601 0.00080469 19595000 3222.3 2748.1 2923.8 2897.3 2960.8 3582.9 2888.5 2325.9 2808.4 2566.1 TRUE FALSE FALSE 2967.251555 2985.633519 3032.1586 2885.31174 2925.494394 2839.766152 2969.543536 3035.056203 2500.325546 2655.271784 1.117494477 1.124417296 1.141939073 1.086635183 1.101768343 1.069482292 1.118357659 1.143030337 0.941645809 1 11.37464382 -9.157197469 0.793966106 0.99594447 1.11208666 0.771429463 0.029714495 0.256950116 0.277763078 0.018514581 0.004675083 6.96E-10 9.157197469 0.116142189 TEQELPRPQS(ph)PSDLDSLDGR ddPTM_HeLa_Curcumin_4h_R1 2 TEQELPRPQSPSDLDSLDGR 20 1 P54259 P54259 ATN1 Atrophin-1 1 0 T(0.003)EQELPRPQS(0.699)PS(0.245)DLDS(0.053)LDGR;TEQELPRPQS(0.749)PS(0.25)DLDS(0.001)LDGR ; 102.84 0.00017218 71263000 3836.9 3023.6 3519.2 3334.2 3392.8 3818.3 2729.88 1888.75 3707.3 2858.6 TRUE FALSE FALSE 3533.205316 3284.946511 3649.624648 3320.403964 3352.343076 3026.341539 2806.473086 2464.62118 3300.618465 2957.936137 1.194483299 1.110553561 1.233841597 1.122540789 1.133338558 1.023126058 0.948794347 0.833223256 1.115851835 1 11.53037519 -4.646654778 1.562847691 1.110837694 0.820527027 0.7178325 0.060725032 0.335110431 1.235987709 0.012379495 0.118919945 2.26E-05 4.646654778 -0.290310667 TEQSLAGPKGS(ph)PS(ph)ESEKER ddPTM_HeLa_Curcumin_4h_R1 1 TEQSLAGPKGSPSESEKER 19 2 Q9NYD6;D6RAG4;V9GYH0 Q9NYD6 HOXC10 Homeobox protein Hox-C10 2 0 TEQS(0.002)LAGPKGS(0.997)PS(0.741)ES(0.259)EKER 61.903 0.014471 11015000 3846.7 3597.8 4486.4 3857.3 4787.2 4307.5 3699.5 2654.7 4359.5 4082 TRUE FALSE FALSE 3542.229636 3908.777801 4652.669931 3841.339515 4730.115767 3414.075944 3803.298013 3464.105809 3881.273757 4223.849196 0.838625972 0.925406571 1.101523685 0.909440498 1.119859054 0.808285473 0.900434139 0.820130087 0.918894964 1 12.04434261 TES(ph)PATAAETASEELDNR ddPTM_HeLa_Curcumin_4h_R1 6 TESPATAAETASEELDNR 18 0 C9JWF0;C9IYK2;C9JJ64;C9JR83;Q9NTJ3-2;Q9NTJ3 C9JWF0 SMC4 Structural maintenance of chromosomes protein 4 1 0 TES(0.972)PAT(0.028)AAETASEELDNR;T(0.357)ES(0.606)PAT(0.036)AAETAS(0.001)EELDNR;T(0.055)ES(0.945)PATAAETASEELDNR;T(0.001)ES(0.763)PAT(0.235)AAET(0.001)ASEELDNR;T(0.094)ES(0.906)PATAAETASEELDNR;T(0.098)ES(0.897)PAT(0.005)AAETASEELDNR ;;;;; 262.74 1.78E-53 1339191900 13172.7 11279.1 11331.52 12411.5 12133.9 12279.32 9318.05 7743.6 13530.7 11428 TRUE FALSE FALSE 12130.0669 12254.01515 11751.4761 12360.1445 11989.21117 9732.450616 9579.489405 10104.58799 12046.41606 11825.12215 1.025787873 1.036269646 0.993772069 1.045244552 1.013876306 0.823031719 0.810096444 0.854501786 1.01871388 1 13.52956747 -5.262537591 24.83768745 1.015518381 0.827298619 0.959394058 0.017889903 11.88024101 268694.0657 0.002614191 0.006167172 5.46E-06 5.262537591 -0.188219763 TES(ph)PQGLPTVQR ddPTM_HeLa_Curcumin_4h_R1 2 TESPQGLPTVQR 12 0 F5H212;P15822;A0A0D9SFF3;P15822-2;P15822-3 F5H212 HIVEP1 Zinc finger protein 40 1 0 T(0.292)ES(0.706)PQGLPT(0.002)VQR;T(0.226)ES(0.756)PQGLPT(0.018)VQR ; 147.39 0.00072531 44994000 3402.1 2549.6 3291.5 3343.3 3208.3 3809.1 2704.1 1226.25 3870.8 2727.5 TRUE FALSE FALSE 3132.820195 2769.976063 3413.485885 3329.46631 3170.043118 3019.049723 2779.969768 1600.12798 3446.182924 2822.280422 1.110031509 0.981467342 1.209477931 1.179707829 1.123220461 1.069719968 0.985008345 0.566962789 1.221063257 1 11.46264563 -4.243844255 2.61144358 1.074215381 0.449294489 0.788208852 0.083007866 0.175061394 1.472927587 0.011064233 0.242981193 5.70E-05 4.243844255 -0.624920893 TES(ph)VPSDINNPVDR ddPTM_HeLa_Curcumin_4h_R1 2 TESVPSDINNPVDR 14 0 A0A2R8Y4X0;A0A0A0MQW1;A0A2R8Y5H9;Q8IVT5-4;Q8IVT5-3;Q8IVT5-2;Q8IVT5;A8MY87 A0A2R8Y4X0 KSR1 Kinase suppressor of Ras 1 1 0 T(0.203)ES(0.789)VPS(0.007)DINNPVDR;T(0.003)ES(0.943)VPS(0.055)DINNPVDR ; 250.46 2.07E-38 190663000 7111.3 6573.5 6419 6899.3 6683.9 7773.4 5858.6 4904.4 6441.5 6104.2 TRUE FALSE FALSE 6548.433101 7141.684049 6656.893787 6870.752525 6604.198858 6161.109216 6022.976548 6399.728983 5734.883566 6316.320496 1.036748073 1.130671576 1.053919571 1.087777691 1.045576909 0.975426947 0.95355778 1.013205234 0.907946892 1 12.62486866 -5.257283683 24.08307775 1.036301373 0.978012759 0.175854413 0.056203281 234.7904373 1360643.088 0.006507686 0.015947396 5.53E-06 5.257283683 -0.058288614 TESAYDWTSLSSSS(ph)IK ddPTM_HeLa_Curcumin_4h_R1 2 TESAYDWTSLSSSSIK 16 0 C9K0J5;Q70E73;C9J164;Q70E73-5;Q70E73-2;Q70E73-8;Q70E73-7;Q70E73-4;Q70E73-3;Q70E73-9;Q70E73-6 C9K0J5 RAPH1 Ras-associated and pleckstrin homology domains-containing protein 1 1 0 TESAYDWTSLS(0.001)S(0.022)S(0.135)S(0.842)IK;TESAYDWTSLS(0.003)S(0.002)S(0.082)S(0.912)IK ; 184.51 7.89E-06 10209400 2113.44 1730.74 2086.4 2215.41 1865.28 3243.1 2096.56 1913.89 1659.08 2068.61 TRUE FALSE FALSE 1946.158994 1880.337454 2163.723819 2206.24322 1843.037754 2570.444503 2155.383831 2497.426251 1477.083075 2140.494044 0.909210189 0.878459559 1.01085253 1.030716823 0.861033816 1.200865058 1.006956239 1.166752254 0.690066426 1 11.06372811 -5.260218592 24.9999636 0.954403856 1.113067687 0.408149794 0.109243509 66.39367894 1359628.769 0.009870924 0.023678035 5.49E-06 5.260218592 0.158663831 TESS(ph)TEGKEQEEK ddPTM_HeLa_Curcumin_4h_R1 2 TESSTEGKEQEEK 13 1 A0A0R4J2E8;A8MXP9;P43243;D6REM6;B3KM87;P43243-2 A0A0R4J2E8 MATR3 Matrin-3 1 0 T(0.031)ES(0.211)S(0.683)T(0.075)EGKEQEEK;T(0.064)ES(0.399)S(0.483)T(0.054)EGKEQEEK ; 82.837 0.0084651 65195000 10483.7 12373.4 11054.6 8898 9861.3 9776.9 7318.6 6273.4 7720.5 9717.1 TRUE FALSE FALSE 9653.904083 13442.90156 11464.2932 8861.182434 9743.710438 7749.060732 7523.940219 8186.130781 6873.580466 10054.7685 0.96013191 1.336967784 1.140184699 0.881291542 0.969063628 0.770685146 0.748295718 0.814154078 0.683613995 1 13.29559225 -5.456507794 1.73221832 1.019626574 0.769171145 0.280987964 0.159095255 0.285069436 1.662976079 0.019515854 0.056130178 3.50E-06 5.456507794 -0.25045543 TET(ph)PPPLASLNVSK ddPTM_HeLa_Curcumin_4h_R1 4 TETPPPLASLNVSK 14 0 Q3MHD2-2;Q3MHD2;K7ELG9 Q3MHD2-2 LSM12 Protein LSM12 homolog 1 0 T(0.001)ET(0.999)PPPLASLNVSK;T(0.011)ET(0.985)PPPLAS(0.003)LNVSK;T(0.161)ET(0.839)PPPLASLNVSK;TET(1)PPPLASLNVSK ;;; 188.63 2.28E-05 142205000 12415.6 11750.1 12171.7 10504.5 12034.9 12657.1 11013.2 7855.6 10679.1 10068.1 TRUE FALSE FALSE 11432.89216 12765.72629 12622.79391 10461.03516 11891.39168 10031.87479 11322.20075 10250.73628 9507.629448 10417.96573 1.097420788 1.22535691 1.211637112 1.00413415 1.141431254 0.962939891 1.086795738 0.983947975 0.912618615 1 13.34678598 -4.253971743 23.06491642 1.069932644 0.983947874 0.066818242 0.09787954 679.7892203 2099469.991 0.012521568 0.164565657 5.57E-05 4.253971743 -0.08598477 TET(ph)QEKNTLPTK ddPTM_HeLa_Curcumin_4h_R1 1 TETQEKNTLPTK 12 1 P63313;CON__P21752 P63313 TMSB10 Thymosin beta-10 1 0 T(0.068)ET(0.932)QEKNTLPTK 137.93 0.013911 7390400 1186.3 874.5 853.37 1080.5 1058.4 2491.7 5222.3 1970.2 1292.3 684.94 TRUE FALSE FALSE 1092.403103 950.0878833 884.9966429 1076.029177 1045.779271 1974.893333 5368.823683 2570.90491 1150.537923 708.741614 1.54132773 1.340527866 1.248687287 1.518224916 1.475543767 2.786478589 7.5751495 3.627421982 1.623353138 1 9.46911595 -4.955215242 5.254722628 1.323997752 5.58799859 0.770985841 0.905616553 0.052548398 3.366488772 0.110683804 0.340264642 1.11E-05 4.955215242 4.264000838 TETDSVGTPQS(ph)NGGMR ddPTM_HeLa_Curcumin_4h_R1 1 TETDSVGTPQSNGGMR 16 0 Q9H0H5;F8VRD2;H0YIK5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 0 TET(0.005)DS(0.08)VGT(0.08)PQS(0.834)NGGMR 101.3 0.0029972 4264500 2419.2 1704.7 1803 1711.2 1834.4 3590.5 3197.3 1609.2 1769 1453.1 TRUE FALSE FALSE 2227.717767 1852.046672 1869.820766 1704.119508 1812.525978 2845.789827 3287.007633 2099.837672 1574.945126 1503.595117 1.481594175 1.231745602 1.243566666 1.13336329 1.205461469 1.892657002 2.186098901 1.396544621 1.04745294 1 10.55420042 -1 0.162855563 1.033531187 4.19490833 0.404994186 0.279192787 51.68512851 0.528786029 0.518133024 39.56389277 0.1 1 3.161377143 TETQAEDTEPDPGESK(ac)GEPR ddPTM_HeLa_Curcumin_4h_R1 1 TETQAEDTEPDPGESKGEPR 20 1 Q92793;Q92793-2;I3L466 Q92793 CREBBP CREB-binding protein 0 1 TETQAEDTEPDPGESK(1)GEPR 221.31 2.16E-27 1164600 347.89 262.16 241.72 347.71 258.85 318.77 289.39 231.9 248.08 177.65 FALSE TRUE FALSE 320.3541394 284.8199422 250.6783558 346.2712682 255.7633828 252.6535087 297.5095045 302.6052425 220.8662447 183.8233243 1.742728463 1.549422215 1.363691778 1.883717801 1.391354355 1.374436621 1.618453511 1.646174356 1.201513712 1 7.522176023 -9.391981499 1.041303777 0.989756212 1.577054944 0.546282741 0.168264225 0.27107097 0.511039304 0.120274296 0.028681728 4.06E-10 9.391981499 0.587298732 TETQEK(ac)NPLPSK ddPTM_HeLa_Curcumin_4h_R1 2 TETQEKNPLPSK 12 1 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 1 ; TETQEK(1)NPLPSK;TETQEK(1)NPLPSK 277.15 7.86E-95 40467000 4763.9 6456.4 5164 4850.3 9923.8 10706.7 8647.3 7958.9 9354.9 4298.8 FALSE TRUE FALSE 4386.832288 7014.462447 5355.382383 4830.230744 9805.465166 8486.009731 8889.919965 10385.53197 8328.690875 4448.18298 0.986207696 1.576927586 1.20394831 1.0858885 2.204375407 1.907747449 1.99855087 2.334780745 1.872380456 1 12.11900042 -5.7053613 0.62665986 0.989723302 2.339531835 0.417819856 0.372894259 0.331131511 0.213421452 0.049827605 0.232980287 1.97E-06 5.7053613 1.349808533 TPTVPDS(ph)PGYMGPTR ddPTM_HeLa_Curcumin_4h_R1 2 TPTVPDSPGYMGPTR 15 0 Q765P7;A0A087WXN9 Q765P7 MTSS1L MTSS1-like protein 1 0 T(0.005)PTVPDS(0.991)PGYMGPT(0.004)R;TPTVPDS(1)PGYMGPTR ; 178.47 6.93E-05 27229000 2461.4 2369.83 1950.45 2219.89 2394.97 3636.4 3298.5 4852.8 2541.7 1962.77 TRUE FALSE FALSE 2266.577593 2574.667545 2022.735393 2210.704683 2366.411547 2882.169649 3391.047033 6332.39638 2262.881869 2030.976111 1.116004063 1.267699571 0.995942484 1.088493691 1.165159715 1.419105638 1.669663672 3.11790786 1.114184385 1 10.98795756 -1.674785245 0.851407223 1.067837557 199.999916 0.978636866 0.088658347 17.06326961 0.163088033 0.014547656 6424.063924 0.021145344 1.674785245 198.9320784 up TETQEKNPLPSK ddPTM_HeLa_Curcumin_4h_R1 3 TETQEKNPLPSK 12 1 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 0 ;; ;; 118.61 0.00057013 122393000 20146.8 17494 19367.9 19111 20075.8 20039.4 19040.2 17919 18097 16598.1 FALSE FALSE TRUE 18552.15952 19006.10341 20085.69141 19031.92375 19836.4092 15883.00255 19574.41677 23382.42061 16111.80438 17174.88274 1.080191335 1.106622019 1.169480556 1.108125397 1.154966208 0.924780844 1.139711814 1.361431165 0.938102729 1 14.06801263 -1 0.11672571 0.962143941 1.691383317 0.356655757 0.096637167 99.34823796 0.802596257 0.464786705 11.78962206 0.1 1 0.729239377 TETQEKNPLPSK(ac)ETIEQEK ddPTM_HeLa_Curcumin_4h_R1 1 TETQEKNPLPSKETIEQEK 19 2 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 1 TETQEKNPLPSK(1)ETIEQEK 149.24 0.00039256 10930000 1185.5 1766.6 1186.4 1414.9 2561.8 3327.6 2575.1 2362.6 3764.1 1568.7 FALSE TRUE FALSE 1091.666424 1919.297032 1230.369028 1409.045519 2531.252208 2637.41825 2647.350375 3082.945864 3351.187647 1623.212208 0.672534631 1.182406726 0.757984089 0.868059956 1.559409297 1.624814203 1.630933012 1.899287011 2.064540687 1 10.66463591 -5.712892571 3.929707655 0.862040574 1.692839793 0.240763323 0.408427739 0.061786646 1.974006971 0.025033859 0.050746901 1.94E-06 5.712892571 0.830799218 TETQEKNPLPSKETIEQEK ddPTM_HeLa_Curcumin_4h_R1 3 TETQEKNPLPSKETIEQEK 19 2 P62328 P62328 TMSB4X Thymosin beta-4;Hematopoietic system regulatory peptide 0 0 ;; ;; 95.205 0.002143 105425000 7621.2 5875.9 6258.6 6869.5 6322.7 8318.4 6030 6122.3 7407.4 7436.3 FALSE FALSE TRUE 7017.973978 6383.786613 6490.549222 6841.075829 6247.305932 6593.070072 6199.185571 7988.961086 6594.826752 7694.710871 0.91205168 0.829633071 0.843507876 0.889062103 0.811896124 0.856831424 0.805642431 1.038240581 0.857059721 1 12.9096514 -8.214777118 0.824752648 0.988752003 0.863342137 0 0.075822241 0.37871956 0.55201862 0.021368657 0.013676635 6.10E-09 8.214777118 -0.125409866 TETQEKNT(ph)LPTK ddPTM_HeLa_Curcumin_4h_R1 1 TETQEKNTLPTK 12 1 P63313;CON__P21752 P63313 TMSB10 Thymosin beta-10 1 0 T(0.002)ET(0.033)QEKNT(0.89)LPT(0.076)K 161.87 0.0016652 11956000 1854.6 1422.8 1519.9 1528.6 1856.1 5201.4 9106.1 3807.7 1944.5 1103.6 TRUE FALSE FALSE 1707.806453 1545.780492 1576.228831 1522.275058 1833.96722 4122.571008 9361.592658 4968.650202 1731.193215 1141.950018 1.49551769 1.353632355 1.380295815 1.333048763 1.605996052 3.610115105 8.197900531 4.351022482 1.515997362 1 10.15728379 -5.037825041 3.3086073 1.293995673 6.277245626 0.820014792 0.910003762 0.057663094 1.276480089 0.112460191 0.346621307 9.17E-06 5.037825041 4.983249952 TETVVDDWDEEFDR ddPTM_HeLa_Curcumin_4h_R1 1 TETVVDDWDEEFDR 14 0 Q9P275;K7EKN3;K7EKL7;K7EIH0 Q9P275 USP36 Ubiquitin carboxyl-terminal hydrolase 36 0 0 114.87 0.019015 2134000 8895.5 7559.8 8832.5 9413.8 9143.9 10853 7911 8002.7 9891.1 8361.6 FALSE FALSE TRUE 8191.411789 8213.235426 9159.84022 9374.84819 9034.864965 8601.965461 8132.961369 10442.68639 8806.071076 8652.164978 0.946747064 0.949269396 1.058676094 1.083526287 1.044231702 0.99419804 0.939991481 1.2069449 1.01778816 1 13.07884546 -6.755958628 24.99243173 0.972231382 1.047484235 0.229102827 0.067290345 147.0385959 670499.676 0.01010035 0.014049408 1.75E-07 6.755958628 0.075252853 TEVNSGFFYK ddPTM_HeLa_Curcumin_4h_R1 1 TEVNSGFFYK 10 0 P40227;P40227-2;Q92526;J3KRI6;Q92526-2 P40227 CCT6A;CCT6B T-complex protein 1 subunit zeta;T-complex protein 1 subunit zeta-2 0 0 150.85 4.79E-17 0 1267 833.52 1146 1105.6 1307.6 1079.2 841.25 970.78 1127.8 825.31 FALSE FALSE TRUE 1166.715613 905.5657547 1188.471768 1101.02532 1292.007724 855.3617549 864.8532109 1266.766353 1004.083162 853.9894611 1.366194393 1.060394532 1.391670298 1.289272726 1.512908277 1.001606921 1.012721176 1.483351272 1.175755917 1 9.738074456 -9.466246251 1.130621738 0.995878681 1.265314421 0.101909254 0.183859397 0.59725457 1.331563269 0.129774193 0.030037837 3.42E-10 9.466246251 0.269435739 TEVQAHS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 TEVQAHSPSR 10 0 A0A669KB77;P11137-3;P11137 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 TEVQAHS(0.872)PS(0.128)R 79.614 0.015246 1581500 1124.7 895.32 1081.2 743.1 936.07 1315.1 1040.4 632.87 1318.8 1044.2 TRUE FALSE FALSE 1035.678808 972.7074713 1121.270223 740.0252491 924.9079766 1042.333436 1069.590824 825.8291496 1174.130939 1080.485872 0.958530634 0.90025006 1.037746306 0.68490044 0.856011171 0.964689555 0.989916529 0.76431277 1.086669405 1 10.07746449 TEVSETARPSSPDT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 TEVSETARPSSPDTR 15 1 O75132 O75132 ZBED4 Zinc finger BED domain-containing protein 4 1 0 TEVSETARPS(0.002)S(0.121)PDT(0.876)R 144.15 0.004801 7324800 3058.3 2078.1 2845.2 2672 3255.3 2766.1 2313.5 986.99 2594 2109.2 TRUE FALSE FALSE 2816.232328 2257.721704 2950.645615 2660.943972 3216.482674 2192.37968 2378.410584 1287.918707 2309.44469 2182.494543 1.290373136 1.03446843 1.351960134 1.219221363 1.47376436 1.004529284 1.089767024 0.59011314 1.058167452 1 11.09176233 -4.031847648 1.680158899 1.171652363 0.074362767 0.577262787 0.150756143 1.157317586 1.946514898 0.023485641 2.451839662 9.29E-05 4.031847648 -1.097289596 TEWLDGK ddPTM_HeLa_Curcumin_4h_R1 2 TEWLDGK 7 0 P62937;P62937-2;P0DN26;A0A0H2UH34;A0A0B4J2A2;A0A075B767;A0A075B759;Q9Y536;F5H284;P0DN37 P62937 PPIA;PPIAL4C;PPIAL4E;PPIAL4A;PPIAL4D "Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase;Peptidyl-prolyl cis-trans isomerase A-like 4A/B/C;Peptidyl-prolyl cis-trans isomerase A-like 4D" 0 0 ; ; 173.59 1.05E-08 110842000 32659 27309 29073 27706 26779 41748 33696 31693 31520 26791 FALSE FALSE TRUE 30074.00569 29669.46827 30150.47096 27591.35991 26459.67791 33088.9942 34641.41907 41356.0498 28062.33486 27721.98526 1.084843146 1.070250489 1.087601435 0.995288024 0.954465478 1.193601176 1.249600949 1.491814148 1.012277245 1 14.75874296 -4.459491233 1.35380256 1.039388611 1.579086122 0.884909633 0.051874801 0.231080241 0.477431746 0.008239735 0.153521909 3.47E-05 4.459491233 0.539697512 ANTIPIIGSPS(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 ANTIPIIGSPSSK 13 0 E9PGM7;O94988-6;O94988-5;O94988-1;O94988 E9PGM7 FAM13A Protein FAM13A 1 0 ANTIPIIGS(0.204)PS(0.682)S(0.115)K 91.789 0.011253 17754000 5125.2 4248.4 4418.6 4770.8 4188.4 4677.8 3453.2 1473.1 4598.5 4203.5 TRUE FALSE FALSE 4719.535012 4615.612765 4582.357203 4751.059694 4138.456066 3707.57155 3550.087498 1922.241409 4094.056055 4349.571312 1.085057509 1.061164983 1.053519272 1.092305276 0.951462976 0.852399302 0.816192503 0.441938129 0.941255071 1 12.0866575 -4.084249847 0.877128693 1.046102041 1.58E-11 0.909808314 0.0558231 0.509948544 0.23616514 0.007910323 0.549523367 8.24E-05 4.084249847 -1.046102041 down TFDQLTPEESKER ddPTM_HeLa_Curcumin_4h_R1 1 TFDQLTPEESKER 13 1 O43852-2;O43852;O43852-4;O43852-3;O43852-9;O43852-5;O43852-12;O43852-13;O43852-14;O43852-7;O43852-11;O43852-8;O43852-10;O43852-6 O43852-2 CALU Calumenin 0 0 70.438 0.01977 0 1483.2 1269.1 1591.5 1457.4 1628.4 1944.6 1295.9 1220.6 1572.6 1282.6 FALSE FALSE TRUE 1365.803155 1378.795349 1650.48239 1451.369665 1608.982394 1541.26804 1332.259466 1592.755321 1400.089714 1327.170255 1.029109227 1.038898622 1.243610143 1.093582123 1.212340608 1.161319005 1.003834634 1.200113788 1.054943561 1 10.37413774 -6.928104793 8.977868001 1.014798848 1.14608998 0.453178246 0.064872769 0.180516853 20.74960458 0.009718073 0.012780512 1.18E-07 6.928104793 0.131291132 TFEHVTSEIGAEEAEEVGVEHLLR ddPTM_HeLa_Curcumin_4h_R1 1 TFEHVTSEIGAEEAEEVGVEHLLR 24 0 H3BNT7;H3BTM8;P51665 H3BNT7 PSMD7 26S proteasome non-ATPase regulatory subunit 7 0 0 142.93 5.92E-07 2254600 666.6 477.39 556.93 604.8 865.96 818.99 584.61 599.09 832.96 528.37 FALSE FALSE TRUE 613.8379066 518.6534644 577.5703157 602.2974979 855.6339926 649.1222421 601.0125832 781.7497831 741.586372 546.7308182 1.122742465 0.948645014 1.056407096 1.101634438 1.565000479 1.187279408 1.099284261 1.429862296 1.356401262 1 9.09468689 -5.976339637 24.93264119 1.050678392 1.299842465 0.297704608 0.158675643 148.2192511 156188.565 0.018276794 0.033128247 1.06E-06 5.976339637 0.249164073 TFIAIKPDGVQR ddPTM_HeLa_Curcumin_4h_R1 4 TFIAIKPDGVQR 12 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;E5RHP0;F6XY72;C9K028;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Nucleoside diphosphate kinase A 0 0 ;;; ;;; 145.23 4.12E-05 165144000 16373.7 13158.4 13282.4 13395.4 12096.4 25845.4 19516 17085.1 16448.7 14248.9 FALSE FALSE TRUE 15077.70437 14295.75346 13774.65743 13339.97338 11952.15833 20484.7727 20063.56644 22294.26834 14644.31876 14744.04821 1.022629888 0.969594867 0.934252061 0.90477006 0.810642922 1.389358771 1.360790886 1.512085963 0.993235952 1 13.84784507 -5.217781537 9.983380744 0.982216768 1.41541352 0.89699401 0.07277799 0.161602417 36.17092038 0.011066873 0.028191916 6.06E-06 5.217781537 0.433196752 TFLDKDAQRLS(ph)PIPEEVPK ddPTM_HeLa_Curcumin_4h_R1 1 TFLDKDAQRLSPIPEEVPK 19 2 Q96T23-3;Q96T23-2;Q96T23;H0YER1;H0YCN2 Q96T23-3 RSF1 Remodeling and spacing factor 1 1 0 TFLDKDAQRLS(1)PIPEEVPK 65.207 0.010328 306040000 2897.7 1891.7 2249.7 2229.1 2336.7 2787.7 2305 1916 2661.3 2374.6 TRUE FALSE FALSE 2668.343987 2055.210119 2333.075861 2219.876575 2308.836379 2209.499596 2369.672096 2500.17958 2369.362048 2457.117173 1.0859653 0.836431466 0.949517543 0.903447584 0.939652534 0.899224351 0.964411515 1.017525581 0.964285332 1 11.26275094 -7.277816056 24.99700215 1.040594725 0.930264813 0.325006562 0.054088965 498.4469291 760816.7796 0.008991948 0.010298603 5.27E-08 7.277816056 -0.110329912 TFLEGDWT(ph)SPSK ddPTM_HeLa_Curcumin_4h_R1 1 TFLEGDWTSPSK 12 0 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 0 TFLEGDWT(0.903)S(0.097)PSK 124.39 0.0090361 200320000 10473 7794.5 9508.6 9906 9735.4 10649 8916.5 5464.9 10035 8743.9 TRUE FALSE FALSE 9644.050999 8468.221848 9860.997081 9865.011597 9619.311713 8440.277361 9166.672992 7131.122853 8934.185606 9047.749874 1.065906013 0.935947829 1.089883918 1.090327621 1.063171711 0.932859272 1.013143944 0.78816534 0.987448341 1 13.14334333 -3.554698023 1.175802419 1.03267541 1.17E-10 0.609914232 0.055258389 3.352248244 1.145414733 0.00792922 6.374427655 0.000278806 3.554698023 -1.03267541 TFLEGDWTS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 3 TFLEGDWTSPSK 12 0 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 0 TFLEGDWT(0.083)S(0.894)PS(0.024)K;TFLEGDWT(0.381)S(0.615)PS(0.004)K;TFLEGDWT(0.058)S(0.939)PS(0.003)K ;; 160.86 0.00019987 260472000 13987.6 12256.1 12391 13008.2 13234 16422.7 12962.4 7393.6 13938.3 12911.9 TRUE FALSE FALSE 12880.4667 13315.46267 12850.22136 12954.37552 13076.19319 13016.4469 13326.09006 9647.874604 12409.30336 13360.58756 0.96406439 0.996622537 0.961800617 0.969596244 0.978713932 0.974242101 0.997417965 0.722114545 0.928799224 1 13.70569583 -4.259255249 24.99981677 0.981155246 0.722114455 0.927496456 0.02110463 25.84940074 295854.8331 0.002171263 0.01918073 5.50E-05 4.259255249 -0.25904079 TFLVWVNEEDHLR ddPTM_HeLa_Curcumin_4h_R1 1 TFLVWVNEEDHLR 13 0 P12277;H0YJG0 P12277 CKB Creatine kinase B-type 0 0 123.28 0.0017598 1011100 723 514.82 663.99 560.19 623.11 770.23 513.12 697.09 771.41 513.54 FALSE FALSE TRUE 665.7737871 559.3187468 688.5980535 557.8720822 615.6798202 610.4756157 527.5167662 909.629532 686.788253 531.3854768 1.252901737 1.052566868 1.295854109 1.049844429 1.158631252 1.1488376 0.992719578 1.711807288 1.292448294 1 9.053614988 -1.000000005 0.021426946 1.93E-11 2.736077478 0.048719906 0.198418014 3550.256651 5.919303934 275.5203216 515.8534851 0.099999999 1.000000005 2.736077478 TFNKDTVIIVS(ph)EPS(ph)EDEESQGLPTMAR ddPTM_HeLa_Curcumin_4h_R1 2 TFNKDTVIIVSEPSEDEESQGLPTMAR 27 1 Q9H4L7-2;Q9H4L7;D6RAY8 Q9H4L7-2 SMARCAD1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 2 0 TFNKDTVIIVS(0.599)EPS(0.689)EDEES(0.643)QGLPT(0.068)MAR;TFNKDTVIIVS(0.648)EPS(0.476)EDEES(0.616)QGLPT(0.26)MAR ; 61.709 0.0047429 260890000 16410 11309.6 12682.6 14980.5 12124.8 16729.6 11228.1 9280 17683.1 15096.8 TRUE FALSE FALSE 15111.13118 12287.15143 13152.62831 14918.51466 11980.21968 13259.69238 11543.13027 12109.42928 15743.30817 15621.41268 0.967334485 0.786558276 0.841961517 0.955004196 0.766910133 0.848815191 0.738929987 0.775181447 1.007803103 1 13.9312373 -6.599533492 0.356811367 1.015360268 0.739331093 0.640809255 0.059200194 0.661754692 0.192804624 0.03272929 0.070492448 2.51E-07 6.599533492 -0.276029175 TFNLEK(ac)QNHTPR ddPTM_HeLa_Curcumin_4h_R1 1 TFNLEKQNHTPR 12 1 Q15233;C9IZL7;C9JYS8;C9J4X2;C9JJ13 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 1 TFNLEK(1)QNHTPR 109 0.0047167 6440800 914.01 1188.5 686.86 669.85 1083.6 1568.3 1061.7 1258 1387 961.32 FALSE TRUE FALSE 841.665144 1291.228644 712.3156358 667.0783382 1070.678778 1243.016902 1091.488445 1641.558409 1234.84957 994.7257984 0.846127793 1.298074953 0.716092452 0.670615298 1.076355695 1.249607584 1.097275698 1.650262224 1.241396948 1 9.958155084 -2.2514012 0.716571079 0.928666387 14.1697979 0.45030967 0.208228829 22.44866078 0.728961263 0.030045364 430.5230503 0.005605299 2.2514012 13.24113151 TFNTS(ph)TGGLLLPSDTKR ddPTM_HeLa_Curcumin_4h_R1 1 TFNTSTGGLLLPSDTKR 17 1 P12956;P12956-2;B1AHC9 P12956 XRCC6 X-ray repair cross-complementing protein 6 1 0 T(0.009)FNT(0.095)S(0.895)T(0.001)GGLLLPSDTKR 170.16 4.36E-14 0 1204.3 899.16 1115.7 1191.2 1107.8 1803.2 1598.8 754.17 1113.9 1221.5 TRUE FALSE FALSE 1108.978384 976.8793838 1157.048823 1186.27113 1094.590209 1429.195994 1643.658025 984.1129612 991.7079568 1263.947034 0.877393082 0.77288 0.915425087 0.938544969 0.866009555 1.130740415 1.300416854 0.778603007 0.784611958 1 10.30372029 -5.257915607 24.96377614 0.921125084 1.092969774 0.242257722 0.139788136 312.6926625 2215223.44 0.018186897 0.044413904 5.52E-06 5.257915607 0.171844691 TFNTSTGGLLLPSDTK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 TFNTSTGGLLLPSDTKR 17 1 P12956;P12956-2;B1AHC9 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 1 ; TFNTSTGGLLLPSDTK(1)R;TFNTSTGGLLLPSDTK(1)R 270.74 2.39E-77 4457100 910.52 982.43 893.26 749.9 1444.91 2040.17 1062.01 1350.37 2189.91 954.63 FALSE TRUE FALSE 838.4513812 1067.346872 926.3650014 746.7971125 1427.680392 1617.015745 1091.807142 1762.091597 1949.682352 987.8033214 0.84880397 1.080525696 0.937803084 0.756018021 1.445308353 1.636981481 1.105287985 1.783848625 1.973755615 1 9.948080009 -5.747015257 23.61332856 0.929580038 1.475468237 0.122273908 0.376017344 49.39478855 80861.6966 0.023944325 0.047682275 1.79E-06 5.747015257 0.5458882 TFNTSTGGLLLPSDTKR ddPTM_HeLa_Curcumin_4h_R1 2 TFNTSTGGLLLPSDTKR 17 1 P12956;P12956-2;B1AHC9 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 0 ; ; 161.2 0.00038384 16850100 8342.1 6143.3 7240.4 7770 7055.5 9216.2 7455.4 7384.3 8831 7886.5 FALSE FALSE TRUE 7681.813982 6674.299478 7508.735593 7737.849799 6971.367771 7304.656232 7664.578459 9635.739077 7862.261394 8160.555288 0.941334715 0.817873201 0.920125571 0.948201382 0.854276152 0.895117547 0.939222662 1.180770026 0.963446863 1 12.99445161 -4.261073681 24.95935645 0.941734469 1.180770099 0.658429145 0.054355536 17.05484922 1163545.05 0.008928762 0.07043963 5.48E-05 4.261073681 0.23903563 TFPLAHS(ph)PQAECEDQLDAQER ddPTM_HeLa_Curcumin_4h_R1 1 TFPLAHSPQAECEDQLDAQER 21 0 A0A1W2PRB5;A0A0J9YVS1;A0A3B3IT55;A0A0G2JNB1;A0A0G2JNT7;Q7Z3B3;A0A0G2JQF5;A0A0G2JQF4;Q7Z3B3-4;Q7Z3B3-2 A0A1W2PRB5 KANSL1 KAT8 regulatory NSL complex subunit 1 1 0 TFPLAHS(1)PQAECEDQLDAQER 135.81 1.72E-05 28438000 1734.5 1244.2 1071.4 1634.1 1427.7 1468.8 986.53 968.11 1519.9 1223.1 TRUE FALSE FALSE 1597.212495 1351.743104 1111.107026 1627.338527 1410.67561 1164.154323 1014.209377 1263.282282 1353.170773 1265.602634 1.26201736 1.068062809 0.877927239 1.285821065 1.114627587 0.919841893 0.80136478 0.998166603 1.069190863 1 10.30560879 -5.235749456 5.241620795 1.115342029 0.89294616 0.337691975 0.120140266 0.163832737 13.37236345 0.019350961 0.04903386 5.81E-06 5.235749456 -0.222395869 TFQARPLS(ph)ADLTK ddPTM_HeLa_Curcumin_4h_R1 1 TFQARPLSADLTK 13 1 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 TFQARPLS(0.638)ADLT(0.362)K 158.65 0.0029175 91925000 2316.2 1992 1847.8 2162.8 1981.7 2742.4 2415.5 562.16 2203.5 1937.5 TRUE FALSE FALSE 2132.870326 2164.179604 1916.281093 2153.850907 1958.069522 2173.595327 2483.272429 733.5599961 1961.781563 2004.827981 1.063866998 1.079483938 0.955833175 1.074332026 0.976677072 1.084180462 1.238646135 0.365896727 0.978528623 1 10.96926274 -4.251039533 24.93392723 1.042459517 0.365896336 0.873780385 0.077971943 334.403048 801724.8375 0.010014498 0.187556151 5.61E-05 4.251039533 -0.676563182 TFRLRS(ph)Y(ph)LAS(ph)HRR ddPTM_HeLa_Curcumin_4h_R1 1 TFRLRSYLASHRR 13 3 A0A3B3IT03;Q6ZNG1 A0A3B3IT03 ZNF600 Zinc finger protein 600 3 0 T(0.02)FRLRS(0.991)Y(0.989)LAS(1)HRR 61.56 0.017314 49317000 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 TFS(ph)ATVR ddPTM_HeLa_Curcumin_4h_R1 1 TFSATVR 7 0 H3BTK3;I3L3X8;H3BSW7;H3BUY4;H3BPY5;H3BNU9;Q9Y2V2 H3BTK3 CARHSP1 Calcium-regulated heat stable protein 1 1 0 TFS(0.969)AT(0.03)VR 140.35 0.0020696 69462000 5230.4 4797.3 4827.1 5117 4917.2 6442.4 4099.1 2423 5613.7 4934.7 TRUE FALSE FALSE 4816.408321 5211.957236 5005.996572 5095.82721 4858.565602 5106.173619 4214.109714 3161.761546 4997.891155 5106.180458 0.943250706 1.020715441 0.980379878 0.997972409 0.951506834 0.999998661 0.825295884 0.619202861 0.978792504 1 12.31802881 -4.40616591 2.223335772 0.978590691 0.580565644 0.953792163 0.025043988 0.074007636 0.518938748 0.003993992 0.050856079 3.92E-05 4.40616591 -0.398025047 TFS(ph)DESNVL ddPTM_HeLa_Curcumin_4h_R1 2 TFSDESNVL 9 0 H7C113;Q8NB49 H7C113 ATP11C Phospholipid-transporting ATPase IG 1 0 T(0.378)FS(0.622)DESNVL;T(0.378)FS(0.622)DESNVL ; 132.01 0.0036029 4267500 5076.5 3711.4 5065 6474.8 4246.8 5488 3664.9 2739 5378.6 5578.4 TRUE FALSE FALSE 4674.689668 4032.196878 5252.713356 6448.008993 4196.159684 4349.726937 3767.72723 3574.108491 4788.581037 5772.248985 0.80985586 0.698548675 0.909994245 1.117070489 0.726954034 0.75355844 0.652731239 0.619188206 0.829586709 1 12.49491782 -2.876963439 0.279664529 0.935123788 1.18E-90 0.346012843 0.121139796 14.6135251 0.46365532 0.061148014 5.437713593 0.001327506 2.876963439 -0.935123788 LPLS(ph)PPLVEDSAFEPSR ddPTM_HeLa_Curcumin_4h_R1 3 LPLSPPLVEDSAFEPSR 17 0 O96007 O96007 MOCS2 Molybdopterin synthase catalytic subunit 1 0 LPLS(1)PPLVEDSAFEPSR;LPLS(1)PPLVEDSAFEPSR;LPLS(1)PPLVEDSAFEPSR ;; 120.59 0.00061983 11912000 1824.24 1415.27 1469.61 1728.41 1981.34 2266.22 2025.95 2617.25 1749.71 1621.7 TRUE FALSE FALSE 1679.849479 1537.599632 1524.075039 1721.258297 1957.713815 1796.180426 2082.792704 3415.237477 1557.771191 1678.053954 1.001070004 0.916299281 0.908239592 1.025746695 1.166657252 1.070394919 1.241195314 2.035236989 0.928320086 1 10.71257339 -1.651740072 0.969239866 0.993889689 200 0.955001083 0.06763646 44.17346568 0.280468564 0.010218332 19231.84271 0.022297693 1.651740072 199.0061103 up TFS(ph)HGS(ph)S(ph)LTRHQIS(ph)HSGEKPY(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 TFSHGSSLTRHQISHSGEKPYK 22 2 A0A087WYF4;E7EVR1;A0A0D9SFG5;Q9NR11-2;Q9NR11 A0A087WYF4 ZNF302 Zinc finger protein 302 5 0 T(0.306)FS(0.81)HGS(0.914)S(0.91)LT(0.072)RHQIS(0.506)HS(0.506)GEKPY(0.975)K 41.53 0.018372 7396800 245.58 273 297.18 474.47 288.23 479.53 370.73 200.33 356.7 278.78 TRUE FALSE FALSE 226.1420839 296.5969035 308.1937522 472.5067689 284.7930455 380.0700726 381.131686 261.4096948 317.5709024 288.4675842 0.783942794 1.02818105 1.068382616 1.637989135 0.987261866 1.317548637 1.32122882 0.906201282 1.100889388 1 8.172265399 -6.73716191 2.817393077 0.900371811 1.235764165 0.220678484 0.206980583 0.201747344 3.294034875 0.031329939 0.044313292 1.83E-07 6.73716191 0.335392354 TFS(ph)LTEVR ddPTM_HeLa_Curcumin_4h_R1 2 TFSLTEVR 8 0 O95239;O95239-2 O95239 KIF4A Chromosome-associated kinesin KIF4A 1 0 TFS(0.979)LT(0.02)EVR;T(0.222)FS(0.768)LT(0.009)EVR ; 145.46 0.0024431 201099000 9503.4 7575.5 8312 8305.7 7584.1 7714.5 7122.4 11038.9 9610.2 7396.8 TRUE FALSE FALSE 8751.195862 8230.292464 8620.050032 8271.333214 7493.664561 6114.42574 7322.235375 14404.60979 8555.985104 7653.838249 1.143373504 1.075315704 1.126238856 1.080677817 0.979072763 0.79887052 0.956674957 1.882011263 1.117868555 1 12.9019677 -4.257750704 24.89633821 1.044857505 1.882011602 0.86844384 0.099244829 98.70683396 666181.2909 0.015361771 0.15258247 5.52E-05 4.257750704 0.837154097 TFSSSSSSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 TFSSSSSSKK 10 1 A0A087WVP4;A0A087X1R1;P53814-5;P53814;P53814-6;H7BZZ8;B5MCI0;P53814-2;A0A096LNK9 A0A087WVP4 SMTN Smoothelin 0 1 TFSSSSSSK(1)K 87.806 0.0038292 0 118.9 68.878 221.78 155.02 110 0 192.48 0 107.07 0 FALSE TRUE FALSE 109.4889395 74.83150741 229.9993619 154.3785683 108.6883218 0 197.8804708 0 95.32468888 0 0 TFSVWYVPEVTGTHK ddPTM_HeLa_Curcumin_4h_R1 2 TFSVWYVPEVTGTHK 15 0 P21333-2;P21333;F8WE98;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 149.3 0.00076269 13808400 5069.8 4158.1 4700.7 3984 4775.1 9095.1 6384.1 5622 4453.8 4387.6 FALSE FALSE TRUE 4668.51998 4517.507636 4874.912077 3967.515264 4718.160051 7208.673737 6563.220664 7336.121919 3965.229283 4540.068773 1.028292789 0.995030662 1.073752914 0.873888802 1.039226559 1.587789546 1.445621419 1.615861408 0.87338529 1 12.14849844 -5.277397379 8.59834204 1.007460396 1.539588354 0.919234617 0.076686507 0.032280904 15.46101708 0.008213834 0.01893561 5.28E-06 5.277397379 0.532127958 TFTTQETITNAETAK ddPTM_HeLa_Curcumin_4h_R1 2 TFTTQETITNAETAK 15 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YX90;A0A0J9YYH3;CON__Q3ZBD7 P06744-2 GPI Glucose-6-phosphate isomerase 0 0 ; ; 268.93 2.72E-101 1896100 791.25 553.44 782.84 691.78 902.57 715.32 470.17 608.92 766.45 641.65 FALSE FALSE TRUE 728.6217276 601.2768875 811.8527391 688.9175977 891.8074422 566.9545687 483.3617048 794.5769049 682.3723526 663.9472897 1.097408994 0.905609371 1.222766855 1.037608871 1.343190124 0.853915028 0.728012166 1.196746966 1.027750792 1 9.374924901 TFVLAGSADS(ph)PELGK ddPTM_HeLa_Curcumin_4h_R1 2 TFVLAGSADSPELGK 15 0 O15061 O15061 SYNM Synemin 1 0 TFVLAGS(0.005)ADS(0.995)PELGK;TFVLAGSADS(1)PELGK ; 223.68 4.95E-15 74459000 4252.4 3540.2 3428.7 4000.6 3666.8 6880.1 5688.2 1912.07 3756.9 2603 TRUE FALSE FALSE 3915.818053 3846.199113 3555.770638 3984.046577 3623.075805 5453.089705 5847.795583 2495.051341 3344.777469 2693.454056 1.453827677 1.427980219 1.320152698 1.479158914 1.34514112 2.024571272 2.171113916 0.926338927 1.241817161 1 11.39524174 -10.23093294 0.172917245 0.328364814 1.77055957 0.180957549 0.338405379 15.86313772 0.534938278 5.243545769 0.715962205 5.88E-11 10.23093294 1.442194756 TFVNITPAEVGVLVGKDR ddPTM_HeLa_Curcumin_4h_R1 1 TFVNITPAEVGVLVGKDR 18 1 P07737;I3L3D5 P07737 PFN1 Profilin-1 0 0 101.38 0.0025637 623440 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 TFVQEDIYDEFVER ddPTM_HeLa_Curcumin_4h_R1 1 TFVQEDIYDEFVER 14 0 S4R3S4;P05091-2;P05091 S4R3S4 ALDH2 "Aldehyde dehydrogenase, mitochondrial" 0 0 140.31 0.0064758 1361900 1286.1 1064.8 1111.6 1370.4 1137.4 1367.5 1177 912.32 1534.2 959.92 FALSE FALSE TRUE 1184.303828 1156.836567 1152.796874 1364.729648 1123.837248 1083.865085 1210.023452 1190.482168 1365.902098 993.2771485 1.192319616 1.164666447 1.160599411 1.373966621 1.131443776 1.091201068 1.218213319 1.198539773 1.375147007 1 9.956052511 -9.155907486 0.649454711 0.981445276 1.1943889 0 0.136349556 0.619159474 0.4133434 0.074505844 0.015718194 6.98E-10 9.155907486 0.212943624 TFVSGACDASIK ddPTM_HeLa_Curcumin_4h_R1 1 TFVSGACDASIK 12 0 P62879;C9JIS1;C9JXA5;E7EP32;P62879-2 P62879 GNB2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0 0 182.28 1.64E-09 1153800 334.18 175.97 305.21 452.82 495.9 499.68 339.08 397.8 391.22 287.11 FALSE FALSE TRUE 307.7293004 191.1800627 316.5213511 450.9463508 489.9867164 396.0407354 348.5936722 519.0873888 348.3041448 297.0870511 1.03582199 0.6435153 1.06541618 1.517892985 1.649303511 1.333079762 1.173372151 1.747256862 1.172397597 1 8.214741915 -6.320736185 5.205398388 0.984492651 1.467761475 0.626042921 0.193854353 0.10545314 6.035771374 0.028042346 0.043477543 4.78E-07 6.320736185 0.483268824 TFWS(ph)PELK ddPTM_HeLa_Curcumin_4h_R1 1 TFWSPELK 8 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-5;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;K7EPP6;O15083 X6RM00 ERC1;ERC2 ELKS/Rab6-interacting/CAST family member 1;ERC protein 2 1 0 T(0.377)FWS(0.623)PELK 112.71 0.010503 94381000 5863.5 4587.4 5265.2 5487.2 5647.2 6443 5084.2 4471.3 5734.4 5133.1 TRUE FALSE FALSE 5399.397788 4983.914415 5460.332944 5464.49542 5579.860828 5106.649172 5226.848969 5834.578787 5105.350667 5311.474843 1.016553396 0.938329666 1.028025757 1.028809433 1.050529466 0.961437138 0.984067349 1.09848563 0.961192666 1 12.3748968 TGAAPIIDVVR ddPTM_HeLa_Curcumin_4h_R1 2 TGAAPIIDVVR 11 0 E9PLL6;P46776;E9PJD9;E9PLX7 E9PLL6 RPL27A 60S ribosomal protein L27a 0 0 ; ; 131.12 0.00079168 21679000 6568.4 6423.4 6016.2 5885.1 6240.9 7519.6 5355.4 5315 6762.3 6174 FALSE FALSE TRUE 6048.504209 6978.610074 6239.165664 5860.749016 6166.481344 5959.950197 5505.658111 6935.519033 6020.492608 6388.54604 0.946773205 1.092362805 0.976617469 0.917383858 0.965240182 0.932911833 0.86180143 1.085617759 0.942388545 1 12.64127191 -6.501285 24.28509534 0.985428241 0.947140991 0.076413052 0.065473779 1136.11939 1277719.958 0.00954045 0.014481761 3.15E-07 6.501285 -0.03828725 TGADTTAAGPLFQQRPYPS(ph)PGAVLR ddPTM_HeLa_Curcumin_4h_R1 2 TGADTTAAGPLFQQRPYPSPGAVLR 25 1 O60828-5;O60828-4;O60828-2;O60828;H7C053 O60828-5 PQBP1 Polyglutamine-binding protein 1 1 0 TGADT(0.003)T(0.004)AAGPLFQQRPY(0.174)PS(0.819)PGAVLR;TGADTTAAGPLFQQRPY(0.005)PS(0.995)PGAVLR ; 73.753 0.00021856 235610000 1129.87 834.52 1044.92 833.93 1072.82 1707.49 1290.87 535.62 1170.66 1107.78 TRUE FALSE FALSE 1040.439597 906.6521903 1083.645654 830.4794186 1060.027322 1353.337327 1327.088338 698.9280723 1042.241527 1146.275273 0.907669931 0.790955028 0.945362497 0.724502603 0.924758082 1.180639031 1.157739655 0.609738419 0.909241918 1 10.16273783 -4.235809038 23.73181986 0.951269106 0.609737547 0.366258482 0.133844655 3580.054504 3314766.728 0.019022489 1.730230226 5.81E-05 4.235809038 -0.34153156 TGAIVDVPVGEELLGR ddPTM_HeLa_Curcumin_4h_R1 1 TGAIVDVPVGEELLGR 16 0 P25705;P25705-2;K7ERX7;K7EK77;K7EQH4;K7EJP1 P25705 ATP5A1 "ATP synthase subunit alpha, mitochondrial" 0 0 99.531 0.0084389 430660 75.114 216.22 196.69 141.34 252.47 193.51 143.85 0 0 209.32 FALSE FALSE TRUE 69.16864764 234.9090933 203.9795044 140.7551725 249.4594601 153.3738447 147.8860438 0 0 216.5938544 0.319347231 1.084560289 0.941760351 0.649857647 1.151738404 0.708117251 0.682780424 0 0 1 7.758848499 -4.284326443 4.617223695 0.751173 2.00E-17 0.294237312 0.336756877 0.151733726 8.094417614 0.041700316 0.347111612 5.20E-05 4.284326443 -0.751173 TGDEEESCGS(ph)PNSVVK ddPTM_HeLa_Curcumin_4h_R1 1 TGDEEESCGSPNSVVK 16 0 A0A384DVK4;Q7Z5L2-2;Q7Z5L2 A0A384DVK4 R3HCC1L Coiled-coil domain-containing protein R3HCC1L 1 0 TGDEEES(0.102)CGS(0.449)PNS(0.449)VVK 114.27 0.0013045 4623400 1138.4 1189 1248 1111.4 1367.1 1865.8 1485.9 911.48 1352.3 1173.8 TRUE FALSE FALSE 1048.294439 1291.771862 1294.251978 1106.801321 1350.798225 1478.812048 1527.590355 1189.386056 1203.956073 1214.589463 0.863085405 1.06354608 1.065588018 0.911255494 1.11214387 1.217540654 1.257700978 0.979249444 0.991245281 1 10.24625304 -5.646497229 4.7316106 0.954029399 1.162403367 0.400937559 0.091741123 0.135565637 5.037178921 0.014254097 0.029047122 2.26E-06 5.646497229 0.208373968 TGDEEESCGSPNS(ph)VVK ddPTM_HeLa_Curcumin_4h_R1 1 TGDEEESCGSPNSVVK 16 0 A0A384DVK4;Q7Z5L2-2;Q7Z5L2 A0A384DVK4 R3HCC1L Coiled-coil domain-containing protein R3HCC1L 1 0 TGDEEES(0.001)CGS(0.015)PNS(0.985)VVK 161.94 0.00024934 4886100 2987.7 2175.2 2121.3 2531.9 2583.2 3755.9 2841 1554.4 2523.1 1692.2 TRUE FALSE FALSE 2751.220392 2363.214595 2199.917244 2521.423669 2552.397027 2976.884002 2920.710814 2028.329404 2246.322242 1751.003824 1.571224662 1.349634172 1.256374894 1.439987528 1.457676444 1.700101371 1.668020808 1.158380911 1.282876834 1 10.77396652 -9.395542986 0.876721924 0.968651365 1.465960493 0.261269439 0.182339007 0.446315857 0.549070986 0.155851939 0.031088209 4.02E-10 9.395542986 0.497309128 TGDLGIPPNPEDRS(ph)PS(ph)PEPIYNSEGK ddPTM_HeLa_Curcumin_4h_R1 6 TGDLGIPPNPEDRSPSPEPIYNSEGK 26 1 Q15637-5;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-6 Q15637-5;Q15637-6 SF1 Splicing factor 1 2 0 T(0.017)GDLGIPPNPEDRS(0.983)PS(0.996)PEPIY(0.002)NS(0.001)EGK;T(0.002)GDLGIPPNPEDRS(0.992)PS(0.968)PEPIY(0.013)NS(0.024)EGK;T(0.195)GDLGIPPNPEDRS(0.973)PS(0.826)PEPIY(0.004)NS(0.002)EGK;T(0.008)GDLGIPPNPEDRS(0.891)PS(0.939)PEPIY(0.094)NS(0.069)EGK;T(0.006)GDLGIPPNPEDRS(0.995)PS(0.99)PEPIY(0.004)NS(0.005)EGK;T(0.001)GDLGIPPNPEDRS(0.962)PS(0.833)PEPIY(0.095)NS(0.11)EGK ;;;;; 70.533 0.00041024 1220133000 33150.9 27489.9 30972.4 29837.8 32679.3 35810 30622.8 28343.3 32781.2 30017 TRUE FALSE FALSE 30526.97128 29866.00446 32120.26439 29714.33909 32289.62069 28382.60234 31481.99335 36985.04169 29185.18437 31060.08852 0.98283594 0.961555678 1.03413306 0.956672711 1.039585598 0.91379657 1.013583504 1.190757769 0.939636227 1 14.92277432 -4.275564553 4.313343876 0.9885852 1.203439862 0.728023634 0.038296202 0.062622582 2.701550597 0.00421222 0.040096569 5.30E-05 4.275564553 0.214854662 TGDLGIPPNPEDRS(ph)PS(ph)PEPIYNSEGKR ddPTM_HeLa_Curcumin_4h_R1 4 TGDLGIPPNPEDRSPSPEPIYNSEGKR 27 2 Q15637-5;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-6 Q15637-5;Q15637-6 SF1 Splicing factor 1 2 0 T(0.03)GDLGIPPNPEDRS(0.994)PS(0.969)PEPIY(0.003)NS(0.003)EGKR;T(0.036)GDLGIPPNPEDRS(0.978)PS(0.961)PEPIY(0.011)NS(0.013)EGKR;T(0.009)GDLGIPPNPEDRS(0.988)PS(0.984)PEPIY(0.009)NS(0.01)EGKR;T(0.026)GDLGIPPNPEDRS(0.934)PS(0.951)PEPIY(0.024)NS(0.066)EGKR ;;; 64.257 0.0010889 339951000 19635.5 15543.9 16136.7 17984.3 14985.9 22384.1 16355.9 16478.8 21958.1 18696.7 TRUE FALSE FALSE 18081.32946 16887.44545 16734.7403 17909.88573 14807.20293 17741.38534 16814.80253 21503.11026 19549.35137 19346.40893 0.93460908 0.872898196 0.865004992 0.925747295 0.765372167 0.917037648 0.869143343 1.111478122 1.010489928 1 14.23977818 -8.169776897 0.947507047 0.989104831 0.89829413 0.173861093 0.082672664 0.595445176 1.130867019 0.024415034 0.017160034 6.76E-09 8.169776897 -0.0908107 TGDLGIPPNPEDRS(ph)PSPEPIYNSEGK ddPTM_HeLa_Curcumin_4h_R1 1 TGDLGIPPNPEDRSPSPEPIYNSEGK 26 1 Q15637-5;Q15637-4;Q15637-7;Q15637-3;Q15637-2;Q15637;Q15637-6 Q15637-5;Q15637-6 SF1 Splicing factor 1 1 0 T(0.005)GDLGIPPNPEDRS(0.487)PS(0.487)PEPIY(0.009)NS(0.013)EGK 57.278 0.0024922 3973600 2469.7 2268.7 2071 2597 2147.9 2679 2120.7 1423.2 2173.1 2355.6 TRUE FALSE FALSE 2274.220639 2464.796319 2147.753082 2586.254302 2122.287695 2123.345201 2180.201134 1857.127128 1934.716367 2437.456925 0.933030084 1.01121636 0.881145041 1.061046157 0.870697518 0.871131375 0.894457298 0.761911774 0.793743819 1 11.25116101 -2.60769762 0.440216815 0.973603463 8.76E-13 0.240258244 0.078552631 9.460457092 0.402663702 0.011573417 6.65916375 0.002467757 2.60769762 -0.973603463 TGEDEDEEDNDALLKENES(ph)PDVRR ddPTM_HeLa_Curcumin_4h_R1 1 TGEDEDEEDNDALLKENESPDVRR 24 2 A0A087WWS1;Q96FV9 A0A087WWS1 THOC1 THO complex subunit 1 1 0 TGEDEDEEDNDALLKENES(1)PDVRR 49.66 0.0075079 17087000 1430.7 1371.6 1581.9 1315 1473 1612.2 1190.6 1141.1 1444.5 1559.3 TRUE FALSE FALSE 1317.458585 1490.154992 1640.526606 1309.558878 1455.435437 1277.811547 1224.005032 1489.016137 1286.041964 1613.485559 0.816529518 0.923562646 1.016759398 0.811633467 0.902044291 0.791957226 0.758609226 0.922856811 0.797058243 1 10.65596495 -6.213052547 24.99740032 0.919137808 0.834106303 0.173907793 0.078736111 511.0984575 264041.4571 0.012831328 0.021278333 6.12E-07 6.213052547 -0.085031505 TGEEDEEEFFCNR ddPTM_HeLa_Curcumin_4h_R1 1 TGEEDEEEFFCNR 13 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 0 0 178.53 0.0015181 4898900 551.11 393.84 656.93 588.93 560.37 648.08 536.15 292.29 545.85 833.6 FALSE FALSE TRUE 507.489062 427.8817747 681.2764037 586.4931637 553.6879537 513.6609026 551.192926 381.4078755 485.9716206 862.567538 0.588347045 0.496055968 0.789823838 0.679938831 0.641906783 0.595502242 0.639014224 0.442177405 0.56340124 1 9.752493612 -9.230857888 0.739197228 1.029315211 0.611977619 0 0.162207962 0.342846342 0.301120556 0.087848319 0.018823562 5.88E-10 9.230857888 -0.417337592 TGEEVGFVVDAK ddPTM_HeLa_Curcumin_4h_R1 1 TGEEVGFVVDAK 12 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 136.48 0.0015706 0 1129.8 913.73 920.39 1214.8 871.79 1345.8 950.78 826.15 1247.6 951.67 FALSE FALSE TRUE 1040.375138 992.7087497 954.5004631 1209.773479 861.3944736 1066.66591 977.4563279 1078.039332 1110.741401 984.7404617 1.056496791 1.008091765 0.969291402 1.228520129 0.874742643 1.083194965 0.992602991 1.09474463 1.12795345 1 9.943599728 -9.526251532 1.234124401 0.999632121 1.038393945 0 0.095996624 1.732203396 4.650519583 0.057609535 0.013254343 2.98E-10 9.526251532 0.038761823 NNK(ac)K(ac)TNK(ac)NK ddPTM_HeLa_Curcumin_4h_R1 2 NNKKTNKNK 9 3 Q92793;Q92793-2 Q92793 CREBBP CREB-binding protein 0 3 ; NNK(1)K(1)TNK(1)NK;NNK(1)K(1)TNK(1)NK 136.96 5.26E-05 53675000 6638 4758.4 5834.7 5472.2 5529.6 6417.5 3940.2 1701.44 6646.2 5050.8 FALSE TRUE FALSE 6112.595296 5169.694893 6050.939115 5449.557486 5463.663131 5086.43816 4050.751407 2220.201224 5917.128488 5226.314924 1.169580361 0.989166357 1.157783104 1.0427151 1.045414065 0.973236063 0.775068373 0.424811986 1.132179858 1 12.35157834 -4.168930842 1.105459396 1.078724583 1.14E-09 0.927026998 0.057232205 0.430196884 0.367122411 0.010376795 0.565233493 6.78E-05 4.168930842 -1.078724582 down K(ac)MAPPPK ddPTM_HeLa_Curcumin_4h_R1 2 KMAPPPK 7 1 P19338 P19338 NCL Nucleolin 0 1 ; K(1)MAPPPK;K(1)MAPPPK 80.18 0.017483 15979100 10943.7 10131.9 11060.3 9405.8 12887.3 12846.3 14498.4 13857.1 9464.9 8505.5 FALSE TRUE FALSE 10077.4946 11007.65629 11470.20445 9366.881292 12733.62736 10181.83257 14905.18608 18082.066 8426.62415 8801.065492 1.145031202 1.250718598 1.303274525 1.064289466 1.44682793 1.156886354 1.693566091 2.054531467 0.957454999 1 13.10346248 -1 0.460799649 1.079466322 25.19023621 0.825624593 0.135638998 21.33990363 0.225022831 0.027113283 491.2635871 0.1 1 24.11076989 up TGGPAYGPSSDVSTAS(ph)ETESEKR ddPTM_HeLa_Curcumin_4h_R1 3 TGGPAYGPSSDVSTASETESEKR 23 1 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 0 TGGPAYGPSSDVST(0.005)AS(0.992)ET(0.002)ES(0.001)EKR;TGGPAYGPSSDVS(0.001)T(0.007)AS(0.986)ET(0.003)ES(0.004)EKR;TGGPAYGPSSDVS(0.002)T(0.024)AS(0.967)ET(0.004)ES(0.002)EKR ;; 147.86 2.81E-06 59034000 7557.3 7233.7 9095.1 8625 10506.9 10113.3 7613.2 5269.1 7255.8 8136.1 TRUE FALSE FALSE 6959.131731 7858.948795 9432.172407 8589.312035 10381.61208 8015.68758 7826.805902 6875.624334 6459.856893 8418.828869 0.826615179 0.93349668 1.12036633 1.020250223 1.233142072 0.952114327 0.929678703 0.816696056 0.767310631 1 13.03940384 -10.09116185 2.917963317 1.001304929 0.948198988 0 0.142177151 1.280544213 19.89839808 0.12094219 0.020037566 8.11E-11 10.09116185 -0.053105941 TGGPAYGPSSDVSTAS(ph)ETESEKREEPNR ddPTM_HeLa_Curcumin_4h_R1 1 TGGPAYGPSSDVSTASETESEKREEPNR 28 2 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 0 TGGPAY(0.001)GPS(0.034)S(0.03)DVS(0.187)T(0.187)AS(0.521)ET(0.033)ES(0.008)EKREEPNR 70.316 0.00019285 17547000 1184.6 1052.5 1132.7 773.11 887.14 1264.4 1055.3 747.05 1199.9 1183.1 TRUE FALSE FALSE 1090.83766 1143.47341 1174.678858 769.9110757 876.5614349 1002.149187 1084.908878 974.822106 1068.273972 1224.212637 0.891052442 0.934048037 0.959538256 0.628903062 0.716020574 0.818607125 0.886209507 0.796284956 0.872621259 1 10.25763845 -6.298058208 24.86972173 0.946676173 0.775495135 0.556713482 0.071639004 311.7639918 211734.2447 0.011935807 0.018232568 5.03E-07 6.298058208 -0.171181038 STSAPQMSPGSSDNQSSS(ph)PQPAQQK ddPTM_HeLa_Curcumin_4h_R1 4 STSAPQMSPGSSDNQSSSPQPAQQK 25 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 0 STSAPQMSPGSSDNQS(0.005)S(0.239)S(0.756)PQPAQQK;STSAPQMSPGSSDNQS(0.001)S(0.218)S(0.781)PQPAQQK;STSAPQMSPGSSDNQS(0.002)S(0.215)S(0.783)PQPAQQK;STSAPQMSPGS(0.003)S(0.008)DNQS(0.057)S(0.309)S(0.623)PQPAQQK ;;; 149.44 1.63E-08 42259100 15979.1 11920.7 13708.7 13883.3 13465.5 15126.2 11543.3 4301.77 15418.8 13768 TRUE FALSE FALSE 14714.33737 12951.07219 14216.75648 13825.85458 13304.93271 11988.85561 11867.17393 5613.35987 13727.39622 14246.43698 1.032843328 0.909074473 0.997916637 0.970478065 0.933913001 0.841533615 0.832992414 0.39401851 0.963566977 1 13.79831353 -4.084076042 0.998156444 1.000361681 4.40E-31 0.910576973 0.052639973 0.48522725 0.295481577 0.007812564 0.563010703 8.24E-05 4.084076042 -1.000361681 down TGGTQTDLFTCGK ddPTM_HeLa_Curcumin_4h_R1 1 TGGTQTDLFTCGK 13 0 A0A1W2PRL9;A0A1W2PPZ5;P23193-2;P23193;B7Z4S1;Q5JRI7;A0A0A0MT58;Q15560-2;Q15560 A0A1W2PRL9 TCEA1;TCEA2 Transcription elongation factor A protein 1;Transcription elongation factor A protein 2 0 0 142.12 1.12E-15 0 248.04 433.63 229 343.44 366.44 502.07 360.76 399.28 416.5 398.07 FALSE FALSE TRUE 228.4073723 471.111045 237.4869414 342.0189363 362.0704423 397.9350225 370.8819547 521.0186339 370.810992 411.9029029 0.554517511 1.143742959 0.576560495 0.830338737 0.879018914 0.966089386 0.900411121 1.264906439 0.900238841 1 8.686160483 -1.000018986 0.716109 0.802596279 63.57445887 0.322522908 0.171900619 275.0455121 1.278889359 0.032555666 27752.38574 0.099995628 1.000018986 62.7718626 TGHILHPEYLQPLPSTPVS(ph)PIELDAK ddPTM_HeLa_Curcumin_4h_R1 1 TGHILHPEYLQPLPSTPVSPIELDAK 26 0 Q96F45-3;Q96F45-2;Q96F45 Q96F45-3 ZNF503 Zinc finger protein 503 1 0 TGHILHPEYLQPLPSTPVS(1)PIELDAK 135.92 2.84E-08 31738000 1933.4 1530.3 1312.7 1530.7 1745.2 2637.4 2223.9 2003.9 1900.9 1830.7 TRUE FALSE FALSE 1780.36935 1662.572313 1361.349817 1524.366369 1724.38963 2090.37351 2286.296649 2614.879885 1692.376026 1894.316689 0.939847788 0.877663341 0.71864954 0.804705136 0.910296383 1.103497384 1.206924197 1.380381591 0.893396567 1 10.88746182 -4.769169519 1.704557676 0.928497932 1.366713915 0.782940375 0.087261156 0.199532409 1.00046356 0.015454641 0.103757112 1.70E-05 4.769169519 0.438215983 TGISDVFAK ddPTM_HeLa_Curcumin_4h_R1 2 TGISDVFAK 9 0 P19338 P19338 NCL Nucleolin 0 0 ; ; 149.94 3.80E-06 34071000 9366 7862.6 8566.5 9654.2 8342.5 10474 8605.3 8551.7 10242.3 8650.8 FALSE FALSE TRUE 8624.671217 8542.208109 8883.982026 9614.253478 8243.021136 8301.574334 8846.741558 11159.07396 9118.745315 8951.414656 0.963498123 0.954285824 0.992466819 1.074048499 0.920862395 0.927403617 0.98830653 1.246626862 1.018693208 1 13.12789998 -4.262601676 6.070824164 0.979490794 1.25340294 0.776561964 0.042558896 0.042182448 7.712667185 0.005645613 0.047565239 5.46E-05 4.262601676 0.273912145 TGKEYIPGQPPLS(ph)QSSDSSPTRNSEPAGLETPEAK ddPTM_HeLa_Curcumin_4h_R1 1 TGKEYIPGQPPLSQSSDSSPTRNSEPAGLETPEAK 35 2 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 0 TGKEYIPGQPPLS(0.219)QS(0.193)S(0.193)DS(0.193)S(0.193)PT(0.004)RNS(0.004)EPAGLETPEAK 62.105 0.00010119 7279400 2308.8 1350.7 1126.6 1488.7 742.75 2241.8 852.89 1241.2 4237.6 2977.7 TRUE FALSE FALSE 2126.056044 1467.448489 1168.352787 1482.540154 733.8931914 1776.82541 876.819798 1619.636166 3772.745882 3081.174853 0.690014733 0.476262646 0.37919068 0.481160669 0.238186155 0.576671398 0.284573203 0.525655389 1.224450433 1 11.58926484 -7.839983645 0.649073993 0.965809746 0.391670244 0.790650896 0.135047847 0.170986368 0.163183296 0.037341429 0.028721286 1.45E-08 7.839983645 -0.574139502 TGKEYIPGQPPLSQSSDS(ph)SPTR ddPTM_HeLa_Curcumin_4h_R1 4 TGKEYIPGQPPLSQSSDSSPTR 22 1 P07814;V9GYZ6 P07814 EPRS Bifunctional glutamate/proline--tRNA ligase;Glutamate--tRNA ligase;Proline--tRNA ligase 1 0 TGKEYIPGQPPLS(0.25)QS(0.106)S(0.071)DS(0.302)S(0.201)PT(0.071)R;TGKEYIPGQPPLS(0.041)QS(0.126)S(0.126)DS(0.393)S(0.238)PT(0.077)R;TGKEYIPGQPPLS(0.003)QS(0.031)S(0.031)DS(0.422)S(0.422)PT(0.091)R;TGKEYIPGQPPLS(0.006)QS(0.072)S(0.048)DS(0.464)S(0.297)PT(0.112)R ;;; 135.63 1.06E-05 104345600 14808.9 9068.4 8264.6 10615.4 5550.84 13562.1 7210.1 8464.6 20411.8 16209.8 TRUE FALSE FALSE 13636.75994 9852.232088 8570.893346 10571.47629 5484.649858 10749.16758 7412.396001 11045.41757 18172.67661 16773.08934 0.813014207 0.587383271 0.510990741 0.630264114 0.326991036 0.640857946 0.441921929 0.658520166 1.083442426 1 14.03386082 -7.495649052 0.94203953 0.954519118 0.518400132 0.768768999 0.108021077 0.151406123 0.274588455 0.022734199 0.023830056 3.19E-08 7.495649052 -0.436118986 TLNAEGTDALGPNVDGTSVS(ph)PGDTEPMIR ddPTM_HeLa_Curcumin_4h_R1 1 TLNAEGTDALGPNVDGTSVSPGDTEPMIR 29 0 Q5M775-4;Q5M775;Q5M775-5;Q5M775-3;Q5M775-2 Q5M775-4 SPECC1 Cytospin-B 1 0 TLNAEGTDALGPNVDGT(0.033)S(0.307)VS(0.653)PGDT(0.008)EPMIR 134.11 3.24E-12 4303700 1096.2 931.35 979.33 943.98 1026.4 1178.8 809.19 330.5 1419.2 967.2 TRUE FALSE FALSE 1009.434613 1011.851744 1015.624831 940.0740609 1014.16085 934.3035922 831.8936936 431.2679286 1263.517311 1000.810128 1.008617504 1.011032678 1.014802711 0.939313097 1.013339915 0.933547299 0.831220299 0.430918829 1.262494528 1 9.966952579 -4.083860142 1.376606367 1.001266505 2.61E-17 0.815186126 0.085890136 0.157154141 0.19133708 0.003217307 0.243923431 8.24E-05 4.083860142 -1.001266505 down TGLSLWDT(ph)SPSYIDK ddPTM_HeLa_Curcumin_4h_R1 2 TGLSLWDTSPSYIDK 15 0 E7EPP6;O14757-2;O14757-3;O14757 E7EPP6 CHEK1 Serine/threonine-protein kinase Chk1 1 0 TGLSLWDT(0.464)S(0.464)PS(0.068)Y(0.005)IDK;TGLSLWDT(0.56)S(0.382)PS(0.057)YIDK ; 115.09 0.0049074 44594000 3312.8 3132.8 3070.1 3668 3612 5825.4 3695.9 4044 3819.1 3112.3 TRUE FALSE FALSE 3050.588384 3403.585273 3183.880607 3652.822788 3568.929259 4617.146374 3799.597007 5276.996984 3400.154285 3220.452193 0.947254671 1.056865641 0.988643959 1.134257728 1.108207495 1.433695052 1.179833383 1.638588828 1.055800267 1 11.65304756 -2.743678006 0.389602192 0.966886129 3.388575077 0.771603616 0.098996179 4.594449623 0.192720057 0.022630589 6.733834141 0.001804355 2.743678006 2.421688949 TGLYNYYDDEKEK ddPTM_HeLa_Curcumin_4h_R1 1 TGLYNYYDDEKEK 13 1 P50454;E9PR70;E9PPV6;E9PKH2 P50454 SERPINH1 Serpin H1 0 0 108.66 0.0037386 64546000 1671.2 1335.4 1759.8 1767.3 1779 1430.7 1120.8 797.29 1560.7 1631.6 FALSE FALSE TRUE 1538.922757 1450.826026 1825.019736 1759.987381 1757.786587 1133.956693 1152.246632 1040.380051 1389.495115 1688.297979 0.911523189 0.859342393 1.080982006 1.042462529 1.041158971 0.671656726 0.682490085 0.616230111 0.823015328 1 10.72135384 -5.251534203 23.98728619 0.970423885 0.659362019 0.759317265 0.079608399 129.7069672 314108.5669 0.010199531 0.025632235 5.60E-06 5.251534203 -0.311061866 SPGS(ph)PVGEGTGSPPK ddPTM_HeLa_Curcumin_4h_R1 1 SPGSPVGEGTGSPPK 15 0 E7EV99;E7ENY0;P35611-5;P35611-2;P35611-6;P35611-4;P35611;P35611-3;A0A0A0MSR2;H0Y9H2 E7EV99 ADD1 Alpha-adducin 1 0 SPGS(1)PVGEGTGSPPK 241.39 4.66E-29 327330000 3740.7 3217 3770.8 3401.6 4099.1 4059.2 4239.1 5413 3954.1 2723.3 TRUE FALSE FALSE 3444.619648 3495.063145 3910.549165 3387.525081 4050.22091 3217.276163 4358.037737 7063.398782 3520.345123 2817.934472 1.222391678 1.240292555 1.387736019 1.202130537 1.43730131 1.141714328 1.546536224 2.506587307 1.249264366 1 11.46042235 -1.644168609 0.917222332 1.152955119 199.9999999 0.88370886 0.136096558 62.77364666 0.463516531 0.024103443 25713.58311 0.022689838 1.644168609 198.8470448 up TGNESGSNLS(ph)DSGSVK ddPTM_HeLa_Curcumin_4h_R1 1 TGNESGSNLSDSGSVK 16 0 Q9UDT6-2;Q9UDT6 Q9UDT6-2 CLIP2 CAP-Gly domain-containing linker protein 2 1 0 TGNESGS(0.005)NLS(0.995)DSGSVK 256.67 2.51E-40 9365100 2064.8 1624.2 1610.8 1549.8 1248.2 2114.9 1208.7 2166 1869.5 1653.3 TRUE FALSE FALSE 1901.368901 1764.588611 1670.497665 1543.387338 1233.31603 1676.2459 1242.612869 2826.403429 1664.420527 1710.752052 1.111422838 1.031469528 0.976469771 0.902168924 0.720920386 0.979829835 0.726354744 1.652140897 0.972917452 1 10.74041496 -6.793563312 3.899280215 1.053291702 0.963044072 0 0.246235848 0.73498488 23.96493455 0.037027155 0.050581949 1.61E-07 6.793563312 -0.09024763 TGPAVAK(ac)AQAGK ddPTM_HeLa_Curcumin_4h_R1 2 TGPAVAKAQAGK 12 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 0 1 ; TGPAVAK(1)AQAGK;TGPAVAK(1)AQAGK 143.24 9.94E-05 3292600 2154.38 2013.52 1852.53 2152.3 2299.58 2176.59 2297.93 1548.5 2815.3 2124.95 FALSE TRUE FALSE 1983.85855 2187.559697 1921.186391 2143.394353 2272.15901 1725.140699 2362.403731 2020.630522 2506.468634 2198.791854 0.902249363 0.994891669 0.873746366 0.974805482 1.033367031 0.784585724 1.074409898 0.91897308 1.139929925 1 11.10249532 -9.61906656 1.439167422 0.999905414 0.940434459 0.149353765 0.090447903 0.889656811 3.317303984 0.050382806 0.011624627 2.40E-10 9.61906656 -0.059470955 TGPPPIS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 TGPPPISPSK 10 0 A0A075B6E4;A0A0A6YYI5;G5E9M7;Q14135-2;Q14135;Q14135-4;A0A096LP98;E7EUJ2;F8WBN7;F8W708;E7ERW0;E7EQU6;E7EWF5 A0A075B6E4 VGLL4 Transcription cofactor vestigial-like protein 4 1 0 T(0.347)GPPPIS(0.503)PS(0.151)K 112.02 0.0067355 74536000 4690.4 3818.5 4053.6 4585 4076.8 4024 2856.5 2278.8 4060.7 3636 TRUE FALSE FALSE 4319.149891 4148.554125 4203.829982 4566.028485 4028.186823 3189.37704 2936.645702 2973.59563 3615.251369 3762.350729 1.147992359 1.102649493 1.117341334 1.213610536 1.070656914 0.847708592 0.780534807 0.790355776 0.960902273 1 11.87741863 -5.211569181 3.555431876 1.089407232 0.79188941 0.790576457 0.066877259 0.084501894 2.183517172 0.010348277 0.027920004 6.14E-06 5.211569181 -0.297517822 TGQLEGAPAPGPAAS(ph)PQTLDHSGATATGGASELK ddPTM_HeLa_Curcumin_4h_R1 1 TGQLEGAPAPGPAASPQTLDHSGATATGGASELK 34 0 P55317-2;P55317 P55317-2 FOXA1 Hepatocyte nuclear factor 3-alpha 1 0 TGQLEGAPAPGPAAS(0.952)PQT(0.048)LDHSGATATGGASELK 118.63 2.64E-18 15678000 3341 2776.4 3064.7 2510.5 3596.8 4366.3 2958.8 811.38 3117.6 2723.7 TRUE FALSE FALSE 3076.556325 3016.379645 3178.280478 2500.112216 3553.910509 3460.680162 3041.815965 1058.766027 2775.60708 2818.348372 1.091616762 1.070265009 1.127710296 0.887084166 1.260990495 1.227910714 1.079290266 0.375668969 0.984834631 1 11.46063424 -4.260958446 24.92224348 1.069713594 0.375668749 0.801009027 0.105340638 12.28117593 636220.8883 0.014419368 0.113927727 5.48E-05 4.260958446 -0.694044845 TGQPAQPAPSAQQPPRPPAS(ph)PDEPSVAASSVGSSR ddPTM_HeLa_Curcumin_4h_R1 2 TGQPAQPAPSAQQPPRPPASPDEPSVAASSVGSSR 35 1 O94964-2 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 1 0 TGQPAQPAPS(0.005)AQQPPRPPAS(0.915)PDEPS(0.038)VAAS(0.018)S(0.022)VGS(0.002)S(0.001)R;TGQPAQPAPS(0.112)AQQPPRPPAS(0.445)PDEPS(0.25)VAAS(0.121)S(0.043)VGS(0.014)S(0.015)R ; 61.382 0.0001778 34329000 2195.8 2181.75 1914.78 2208 1910.9 1621.8 1199.95 1166.17 2832.5 1995.19 TRUE FALSE FALSE 2022.000113 2370.330748 1985.743431 2198.863881 1888.113766 1285.420399 1233.617367 1521.729865 2521.781837 2064.522704 0.979403186 1.1481253 0.961841411 1.0650713 0.914552193 0.622623523 0.597531509 0.737085556 1.221484187 1 11.01159257 -5.368430599 3.728051302 1.00509502 0.646177255 0.785799832 0.092718137 0.056592904 1.420512904 0.008698634 0.020693826 4.28E-06 5.368430599 -0.358917765 TGQPAQPAPSAQQPPRPPASPDEPSVAASSVGS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 TGQPAQPAPSAQQPPRPPASPDEPSVAASSVGSSR 35 1 O94964-2 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 1 0 TGQPAQPAPS(0.002)AQQPPRPPAS(0.103)PDEPS(0.013)VAAS(0.201)S(0.206)VGS(0.238)S(0.238)R 49.942 0.0037866 11238000 909.52 526.6 621.9 673.06 473.03 427.14 556.39 364.41 699.59 516.6 TRUE FALSE FALSE 837.5305323 572.1169575 644.9481611 670.2750561 467.3894262 338.5463491 572.000806 475.5169315 622.8467273 534.5518115 1.566790186 1.070274097 1.206521327 1.253901009 0.874357576 0.633327475 1.070056809 0.889561912 1.165175599 1 9.062185978 -5.757863309 8.43346743 1.251618515 0.864057935 0.47544433 0.173618129 0.094688722 60.38488839 0.03416268 0.065571948 1.75E-06 5.757863309 -0.387560581 TGRDT(ph)PENGETAIGAENSEK ddPTM_HeLa_Curcumin_4h_R1 2 TGRDTPENGETAIGAENSEK 20 1 Q8N3X1-2;Q8N3X1 Q8N3X1-2 FNBP4 Formin-binding protein 4 1 0 T(0.085)GRDT(0.915)PENGETAIGAENSEK;T(0.003)GRDT(0.997)PENGETAIGAENSEK ; 144.45 6.89E-05 146326000 7462.4 6106.6 7228 6656.1 7649.4 7449.8 6691.4 4521.4 5639.6 5518.7 TRUE FALSE FALSE 6871.743166 6634.427294 7495.876038 6628.558822 7558.185901 5904.627503 6879.142675 5899.954046 5020.94999 5710.474414 1.203357667 1.161799671 1.312653817 1.160772003 1.323565321 1.033999467 1.204653445 1.033181067 0.87925269 1 12.47939489 -9.204056878 0.875306816 0.996483312 1.1839285 0.448843824 0.100179653 0.516677098 0.691892466 0.063468802 0.016563357 6.25E-10 9.204056878 0.187445188 TGS(ph)CSELDACPSK ddPTM_HeLa_Curcumin_4h_R1 1 TGSCSELDACPSK 13 0 Q9H1H9-3;Q9H1H9-4;Q9H1H9-2;A0A1B0GUA8;Q9H1H9;H0Y9Z7 Q9H1H9-3 KIF13A Kinesin-like protein KIF13A 1 0 T(0.02)GS(0.911)CS(0.069)ELDACPSK 239.38 8.40E-27 108240000 4299.5 3207.8 3900.1 3617.5 3616.5 5737.5 3778.7 3189.7 4861.5 3859 TRUE FALSE FALSE 3959.190038 3485.067938 4044.641137 3602.531744 3573.3756 4547.477825 3884.720152 4162.224846 4328.205613 3993.099963 0.99150787 0.872772525 1.012907559 0.902189221 0.894887589 1.138833955 0.972858228 1.042354282 1.083921177 1 11.96329347 -5.269424306 24.9982248 0.974678495 1.043499764 0.225938683 0.070997251 713.7459733 2234508.997 0.008938395 0.02036271 5.38E-06 5.269424306 0.068821269 TGS(ph)EPALSPAVVR ddPTM_HeLa_Curcumin_4h_R1 1 TGSEPALSPAVVR 13 0 O75815;O75815-3;O75815-2 O75815 BCAR3 Breast cancer anti-estrogen resistance protein 3 1 0 T(0.014)GS(0.983)EPALS(0.003)PAVVR 109.6 0.0041345 28937000 1376.8 1115.6 1266.8 1320.6 1202.7 2235.4 2199.7 904.22 1075 1385.4 TRUE FALSE FALSE 1267.824827 1212.027493 1313.748722 1315.135707 1188.358588 1771.752842 2261.417662 1179.912515 957.0751895 1433.542547 0.88439986 0.845477168 0.916435111 0.917402633 0.828966389 1.235926234 1.577502995 0.82307464 0.667629427 1 10.48536901 -5.248166368 23.02088603 0.925449164 1.248701604 0.370490595 0.194678254 190.4658335 330343.4323 0.022655724 0.057293703 5.65E-06 5.248166368 0.32325244 TGS(ph)ESSQTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 6 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 T(0.003)GS(0.96)ES(0.027)S(0.009)QT(0.001)GTSTTSSR;T(0.005)GS(0.903)ES(0.057)S(0.01)QT(0.001)GT(0.003)S(0.01)T(0.003)T(0.001)S(0.003)S(0.002)R;T(0.031)GS(0.955)ES(0.007)S(0.006)QTGTSTTSSR;T(0.001)GS(0.963)ES(0.035)S(0.002)QTGTSTTSSR;T(0.188)GS(0.81)ES(0.001)S(0.001)QTGTSTTSSR;T(0.028)GS(0.81)ES(0.093)S(0.067)QT(0.001)GTSTTSSR ;;;;; 157.83 0.0002867 1060436930 3106.51 3376.416 3224.095 3476.55 2564.57 3117.34 2379.6 2080.693 3411.315 3376.8 TRUE FALSE FALSE 2860.626456 3668.258354 3343.582797 3462.164957 2533.989178 2470.768544 2446.365172 2715.086717 3037.102279 3494.143549 0.818691738 1.049830467 0.956910542 0.990847946 0.725210382 0.707117069 0.70013299 0.77703926 0.869197913 1 11.77072316 -5.751054483 24.86319415 0.931999148 0.723982016 0.727425745 0.065608274 103.0743645 246775.5346 0.011909162 0.023608494 1.77E-06 5.751054483 -0.208017132 TGS(ph)GQGPSSTGQPGR ddPTM_HeLa_Curcumin_4h_R1 1 TGSGQGPSSTGQPGR 15 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 T(0.417)GS(0.576)GQGPS(0.007)STGQPGR 99.915 0.0039909 1974500 422.88 467.8 386.18 447.2 217.06 492.46 469.02 156.29 352.49 277.63 TRUE FALSE FALSE 389.4086018 508.2345475 400.4921705 445.3496049 214.4717013 390.3182448 482.1794389 203.9421015 313.8227289 287.2776218 1.355513177 1.769140751 1.394094562 1.550241199 0.746565987 1.358679602 1.678444133 0.709912941 1.092402279 1 8.166301805 -9.07369935 1.041196598 1.015069677 1.334762743 0.094698481 0.331926264 0.788283917 1.634320491 0.16495855 0.059074832 8.44E-10 9.07369935 0.319693067 SSINSVDGES(ph)PNGSSDR ddPTM_HeLa_Curcumin_4h_R1 1 SSINSVDGESPNGSSDR 17 0 E9PGE5;Q9NUY8-2;Q9NUY8 E9PGE5 TBC1D23 TBC1 domain family member 23 1 0 SSINS(0.001)VDGES(0.999)PNGSSDR 280.31 9.55E-66 51765000 2598.3 2418.1 2270.6 2140.1 2387.3 2850.2 1982.5 772.28 2817.2 2273.3 TRUE FALSE FALSE 2392.641813 2627.109789 2354.750433 2131.244833 2358.833007 2259.036392 2038.123614 1007.744617 2508.160208 2352.297006 1.017151239 1.116827417 1.001042992 0.906027099 1.002778561 0.960353385 0.866439744 0.428408749 1.066260001 1 11.19985451 -4.083138517 1.549156369 1.007807331 1.77E-16 0.919507886 0.051773537 0.313202488 0.493704382 0.007082746 0.543382023 8.26E-05 4.083138517 -1.007807331 down TGS(ph)PGPELLFHEGQQK ddPTM_HeLa_Curcumin_4h_R1 1 TGSPGPELLFHEGQQK 16 0 A6NHN7;A6NHB5;A6NL54;Q14202-2;Q14202;Q14202-3 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 0 T(0.087)GS(0.913)PGPELLFHEGQQK 166.3 9.06E-05 25550000 3733.4 3109.5 3487.1 3648.4 4015.9 4596.1 4390.9 2762.5 3341 3150.5 TRUE FALSE FALSE 3437.897451 3378.271324 3616.334994 3633.303887 3968.013015 3642.817051 4514.096836 3604.773533 2974.500659 3259.97964 1.054576356 1.036286019 1.109312141 1.114517355 1.217189508 1.117435522 1.384700929 1.105765658 0.912429213 1 11.67064724 -6.118246718 0.659654912 1.018335256 1.240421147 0.555207696 0.080710814 0.391633787 0.321474314 0.014060331 0.04165753 7.62E-07 6.118246718 0.222085891 TGS(ph)PGPELLFHEGQQKR ddPTM_HeLa_Curcumin_4h_R1 1 TGSPGPELLFHEGQQKR 17 1 A6NHN7;A6NHB5;A6NL54;Q14202-2;Q14202;Q14202-3 A6NHN7 ZMYM3 Zinc finger MYM-type protein 3 1 0 T(0.161)GS(0.839)PGPELLFHEGQQKR 92.671 0.0033503 6312700 5615.3 4468.5 4306.2 5072.5 4419.6 6177.8 5139.1 3687.2 6352.6 5736.7 TRUE FALSE FALSE 5170.84308 4854.737229 4465.79156 5051.511339 4366.899157 4896.454642 5283.289315 4811.410306 5655.735673 5936.049898 0.871091579 0.817839693 0.752317052 0.850988692 0.735657421 0.8248675 0.890034519 0.810540745 0.95277765 1 12.5352875 -8.344337314 0.681815545 0.992157516 0.81091767 0.668280584 0.044963746 0.257071532 0.256098399 0.021535077 0.011146827 4.53E-09 8.344337314 -0.181239846 TGS(ph)QGQCTQVR ddPTM_HeLa_Curcumin_4h_R1 2 TGSQGQCTQVR 11 0 P62857 P62857 RPS28 40S ribosomal protein S28 1 0 T(0.15)GS(0.85)QGQCTQVR;T(0.165)GS(0.834)QGQCT(0.001)QVR ; 154.72 0.00044793 108918000 1941.18 1247.86 644.61 1071.89 1204.64 2593.37 2727.75 921.71 2237.82 1137.56 TRUE FALSE FALSE 1787.533555 1355.719458 668.4998137 1067.454803 1190.275455 2055.475829 2804.283324 1202.735136 1992.336745 1177.090125 1.518603815 1.151755018 0.567925768 0.906859025 1.011201631 1.746234876 2.382386245 1.021786786 1.692594902 1 10.20100907 -5.249280377 20.60129831 1.151435265 1.783362112 0.285939823 0.425531546 65.8855352 111626.7199 0.057806494 0.145483957 5.63E-06 5.249280377 0.631926848 TGS(ph)SSSILSASSESSEK ddPTM_HeLa_Curcumin_4h_R1 1 TGSSSSILSASSESSEK 17 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 TGS(0.745)S(0.117)S(0.117)S(0.02)ILSASSESSEK 234.82 1.28E-22 13212000 2084.5 1798.4 1708.6 1484.2 2004 2995.1 2677.3 1169.8 2396.9 2128.8 TRUE FALSE FALSE 1919.509625 1953.845682 1771.922219 1478.058774 1980.103609 2373.882498 2752.417832 1526.466635 2133.966067 2202.775642 0.871404963 0.886992595 0.80440431 0.670998329 0.898912977 1.077677841 1.249522548 0.692974176 0.968762332 1 11.10510684 -5.275128568 22.82072268 0.900607858 1.031004617 0.112617149 0.155477847 383.000789 638487.5254 0.022279439 0.05014386 5.31E-06 5.275128568 0.130396759 SPS(ph)PPDGSPAATPEIR ddPTM_HeLa_Curcumin_4h_R1 2 SPSPPDGSPAATPEIR 16 0 O00499-6;O00499-2;O00499;O00499-9;O00499-7;O00499-4;O00499-11;O00499-3;O00499-5;O00499-10;O00499-8 O00499-6 BIN1 Myc box-dependent-interacting protein 1 1 0 S(0.021)PS(0.979)PPDGSPAATPEIR;S(0.001)PS(0.995)PPDGS(0.004)PAATPEIR ; 244.57 2.49E-30 514907100 1686.68 1323.65 1352.75 1521.62 1638.72 2173.5 1969.24 2692.3 1943.73 1309.29 TRUE FALSE FALSE 1553.177498 1438.060408 1402.884105 1515.32394 1619.179334 1722.6916 2024.491574 3513.169876 1730.507682 1354.78773 1.146436053 1.06146548 1.035501041 1.118495471 1.195153527 1.271558312 1.494323819 2.593151531 1.277327543 1 10.40385111 -1.62133922 0.887127887 1.071281695 200 0.964855222 0.083670217 21.87850076 0.169463104 0.010467267 8649.34666 0.023914471 1.62133922 198.9287183 up RLS(ph)ASSTGSTR ddPTM_HeLa_Curcumin_4h_R1 2 RLSASSTGSTR 11 1 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 0 RLS(0.796)AS(0.068)S(0.068)T(0.068)GSTR;RLS(0.882)AS(0.077)S(0.031)T(0.009)GSTR ; 132.86 0.0038062 48953000 7326.3 6294.3 6699.8 6905.1 6601.9 7915.7 5596.9 2155.54 7644.1 6138 TRUE FALSE FALSE 6746.415624 6838.351245 6948.100482 6876.528526 6523.176654 6273.894592 5753.933951 2812.754223 6805.561355 6351.295043 1.062211026 1.076686124 1.093965945 1.082697069 1.027062451 0.987813438 0.905946569 0.442863102 1.071523415 1 12.63283508 -4.082188285 1.607580302 1.041568706 1.01E-18 0.969477766 0.032424434 0.237177824 0.405002366 0.005686338 0.439610264 8.28E-05 4.082188285 -1.041568706 down GLNNDS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 GLNNDSPER 9 0 G5EA48;Q7Z6B7-2;Q7Z6B7 G5EA48 SRGAP1 SLIT-ROBO Rho GTPase-activating protein 1 1 0 GLNNDS(1)PER 142.89 0.0021878 43498000 3223 3120.8 2229.2 2881.7 2631.5 3177.3 2339 855.36 3234.4 2845.9 TRUE FALSE FALSE 2967.896149 3390.548046 2311.816113 2869.776289 2600.121081 2518.292164 2404.626045 1116.155326 2879.594412 2944.794813 1.007844803 1.151369878 0.785051679 0.974525042 0.882954924 0.855167278 0.816568283 0.379026519 0.977859102 1 11.5239514 -4.081671364 0.8995229 0.994987809 1.12E-39 0.771403603 0.094110693 0.930311657 0.453020337 0.013847013 0.976980775 8.29E-05 4.081671364 -0.994987809 down VEVAAPAHRGT(ph)PDTDLEVQR ddPTM_HeLa_Curcumin_4h_R1 2 VEVAAPAHRGTPDTDLEVQR 20 1 P0C7T5 P0C7T5 ATXN1L Ataxin-1-like 1 0 VEVAAPAHRGT(0.974)PDT(0.026)DLEVQR;VEVAAPAHRGT(0.97)PDT(0.03)DLEVQR ; 63.443 0.0041317 45234000 10557.7 7982 9375.5 9671.7 8114.7 10027.5 7218.3 2840.9 10921.8 7548.1 TRUE FALSE FALSE 9722.046905 8671.928513 9722.964278 9631.681068 8017.937502 7947.683467 7420.826071 3707.077332 9723.705865 7810.395913 1.244757246 1.110305881 1.244874701 1.233187303 1.02657248 1.017577541 0.950121627 0.474633728 1.24496965 1 12.93117997 -4.081148589 1.258086346 1.130130405 5.00E-16 0.833680971 0.090827738 0.755126011 0.752390722 0.016087388 1.222742841 8.30E-05 4.081148589 -1.130130405 down TGSES(ph)SQTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 2 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 TGS(0.005)ES(0.634)S(0.359)QT(0.003)GTSTTSSR;T(0.034)GS(0.009)ES(0.476)S(0.476)QT(0.006)GTSTTSSR ; 251.28 5.10E-40 1047128000 4641.3 4198.8 4333.76 3868.3 3834 4635.6 4037.11 2754.83 4243.3 4322.3 TRUE FALSE FALSE 4273.936208 4561.725563 4494.372958 3852.294 3788.282054 3674.124306 4150.380441 3594.764985 3777.820606 4472.499603 0.955603485 1.019949909 1.004890633 0.861329087 0.847016745 0.821492372 0.927977822 0.803748531 0.844677684 1 12.12686564 -6.253074729 22.58385153 0.98398487 0.85451 0.488352701 0.056005424 58.69209214 158462.6238 0.005229076 0.008561982 5.58E-07 6.253074729 -0.12947487 TGSESSQTGTSTTS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 1 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 1 0 TGSESSQTGT(0.001)S(0.006)T(0.007)T(0.047)S(0.468)S(0.468)R 88.187 0.0070108 5686100 1579.7 1384.9 1421.5 1434 1524.5 1658 1483.3 1237.9 1596.1 1394.4 TRUE FALSE FALSE 1454.665078 1504.604585 1474.18204 1428.066488 1506.321333 1314.11211 1524.917406 1615.330011 1421.011823 1442.855296 1.008185008 1.042796592 1.021711633 0.989750318 1.043986419 0.910771935 1.056874802 1.119537084 0.98486094 1 10.4947109 -4.52487898 24.99999895 1.004142628 1.103871547 0.518684311 0.036008674 28.05435754 350646.7433 0.004440068 0.016838023 2.99E-05 4.52487898 0.099728919 TGSESSQTGTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 2 TGSESSQTGTSTTSSR 16 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 0 ; ; 181.67 2.88E-07 3092800 0 0 0 78.759 0 0 0 0 0 115.62 FALSE FALSE TRUE 0 0 0 78.43311613 0 0 0 0 0 119.6377864 0 0 0 0.655588159 0 0 0 0 0 1 6.902529312 -9.242038914 0.777628054 1.057412873 0.079777049 0 0.363833998 0.297416948 0.294019289 0.183489136 0.040610945 5.73E-10 9.242038914 -0.977635824 TGSGGVASSSESNR ddPTM_HeLa_Curcumin_4h_R1 1 TGSGGVASSSESNR 14 0 K7EMT0;Q15428 K7EMT0 SF3A2 Splicing factor 3A subunit 2 0 0 193.28 1.62E-12 964560 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 TGSGGVASSSESNRDR ddPTM_HeLa_Curcumin_4h_R1 1 TGSGGVASSSESNRDR 16 1 K7EMT0;Q15428 K7EMT0 SF3A2 Splicing factor 3A subunit 2 0 0 95.822 0.0034436 851360 381.85 320.43 296.7 278.95 383.58 376.27 267.41 271.72 387.12 251.96 FALSE FALSE TRUE 351.6261696 348.1265414 307.695963 277.7957788 379.006059 298.2273606 274.9128049 354.5661772 344.6539045 260.7155912 1.348696363 1.335273198 1.180197784 1.06551272 1.453714591 1.143880039 1.054454793 1.359973047 1.321953562 1 8.026333051 -9.472385409 1.221454855 1.000494214 1.24686186 0 0.159614102 0.423842789 1.134960214 0.086773825 0.021515844 3.37E-10 9.472385409 0.246367646 TGSGQGPS(ph)STGQPGR ddPTM_HeLa_Curcumin_4h_R1 1 TGSGQGPSSTGQPGR 15 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 T(0.106)GS(0.262)GQGPS(0.31)S(0.31)T(0.012)GQPGR 135.55 0.00061904 1714900 273.21 254.62 376.99 360.41 294.82 431.01 315.58 285.94 340.74 359.91 TRUE FALSE FALSE 251.5851402 276.6282182 390.961581 358.9187189 291.3044641 341.6136675 324.4343255 373.1217897 303.3616745 372.4168457 0.675547154 0.742791905 1.04979564 0.963755327 0.78220002 0.91728844 0.871159104 1.00189289 0.814575597 1 8.540774522 -6.776357559 24.99094412 0.83470563 0.922394448 0.233558423 0.103958862 487.8405141 817228.8499 0.023000307 0.030297315 1.67E-07 6.776357559 0.087688819 TGSGQGPSS(ph)TGQPGR ddPTM_HeLa_Curcumin_4h_R1 1 TGSGQGPSSTGQPGR 15 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 T(0.297)GS(0.08)GQGPS(0.175)S(0.395)T(0.054)GQPGR 145.94 0.00048306 11563000 1297 779.49 929.14 1042.3 980.34 1734.4 1758.3 941.96 966.23 711.46 TRUE FALSE FALSE 1194.341081 846.8656423 963.5747458 1037.987239 968.6500858 1374.665889 1807.633166 1229.159268 860.2369864 736.183182 1.622342252 1.150346358 1.308879052 1.409957826 1.315773179 1.86728782 2.455412199 1.669637799 1.168509425 1 9.523920982 -1 0.179738456 1.084015094 5.382016915 0.512848538 0.283691777 38.32135684 0.415727286 0.405786957 45.23970123 0.1 1 4.298001821 TGSGQGPSSTGQPGR ddPTM_HeLa_Curcumin_4h_R1 1 TGSGQGPSSTGQPGR 15 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 0 0 107.17 0.0031342 261250 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 TGSGS(ph)PFAGNS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 2 TGSGSPFAGNSPAR 14 0 M0QY97;Q9UPT8 M0QY97 ZC3H4 Zinc finger CCCH domain-containing protein 4 2 0 T(0.01)GS(0.398)GS(0.592)PFAGNS(1)PAR;T(0.025)GS(0.234)GS(0.742)PFAGNS(1)PAR ; 165.16 0.00051683 201332000 8962.1 8812.4 8627.1 8535.7 10409.4 8895.7 8379.6 5882.7 7788.7 7492.5 TRUE FALSE FALSE 8252.740328 9574.104589 8946.827915 8500.381535 10285.2747 7050.631545 8614.709023 7676.308149 6934.299096 7752.863817 1.064476369 1.234912003 1.154002976 1.09641827 1.326641993 0.909422855 1.111164755 0.990125498 0.894417761 1 12.92051361 -7.783590496 2.134542515 1.021420968 1.118238206 0.192935736 0.117053211 0.415335766 3.935506818 0.021523613 0.020982576 1.65E-08 7.783590496 0.096817237 TGSGS(ph)PFAGNS(ph)PAREGEQDAASLK ddPTM_HeLa_Curcumin_4h_R1 1 TGSGSPFAGNSPAREGEQDAASLK 24 1 M0QY97;Q9UPT8 M0QY97 ZC3H4 Zinc finger CCCH domain-containing protein 4 2 0 T(0.025)GS(0.083)GS(0.894)PFAGNS(0.6)PAREGEQDAAS(0.398)LK 54.308 0.0074661 28839000 5506.3 4450.2 5616.2 4705.3 5695.4 5213.3 4457 3287.1 4803 4415.1 TRUE FALSE FALSE 5070.470545 4834.855458 5824.341313 4685.830715 5627.486075 4132.002814 4582.051425 4289.321658 4276.122917 4568.524396 1.109870519 1.058296955 1.274884581 1.02567707 1.231795124 0.904450202 1.002960918 0.938885576 0.935996516 1 12.15751254 -5.220593041 24.9637899 1.079009469 0.95418509 0.297388304 0.098852532 514.1426511 314224.4613 0.012888693 0.032859481 6.02E-06 5.220593041 -0.124824379 TGSGS(ph)PFAGNS(ph)PAREGEQDAASLKDVFK ddPTM_HeLa_Curcumin_4h_R1 3 TGSGSPFAGNSPAREGEQDAASLKDVFK 28 2 M0QY97;Q9UPT8 M0QY97 ZC3H4 Zinc finger CCCH domain-containing protein 4 2 0 T(0.006)GS(0.034)GS(0.961)PFAGNS(0.999)PAREGEQDAASLKDVFK;T(0.093)GS(0.117)GS(0.818)PFAGNS(0.961)PAREGEQDAAS(0.012)LKDVFK;T(0.241)GS(0.5)GS(0.723)PFAGNS(0.528)PAREGEQDAAS(0.007)LKDVFK ;; 92.49 2.05E-07 65997700 8036.9 5552.2 5297.4 7213 5540.5 7456.5 5037 3982.9 8420.3 6934.4 TRUE FALSE FALSE 7400.770885 6032.107428 5493.726304 7183.154517 5474.433156 5909.937848 5178.324664 5197.267875 7496.614157 7175.369884 1.031413154 0.840668499 0.76563667 1.00108491 0.762947868 0.823642257 0.721680519 0.724320552 1.044770413 1 12.80883749 -6.223437558 0.480948677 1.024333455 0.71111808 0.629799288 0.076779023 0.537860408 0.232861241 0.023576385 0.07188439 5.98E-07 6.223437558 -0.313215376 TGSGS(ph)PFAGNSPAR ddPTM_HeLa_Curcumin_4h_R1 1 TGSGSPFAGNSPAR 14 0 M0QY97;Q9UPT8 M0QY97 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 0 T(0.02)GS(0.308)GS(0.672)PFAGNSPAR 123.68 0.0014832 83255000 2916.6 2610 2781.5 2884.4 2846.7 3669.9 2774.8 1573.3 3055.5 2894.6 TRUE FALSE FALSE 2685.748032 2835.59677 2884.584837 2872.465117 2812.754962 2908.721372 2852.65342 2052.991927 2720.319294 2995.187135 0.89668789 0.946717732 0.963073326 0.959026928 0.939091561 0.971131766 0.952412418 0.68543027 0.908230161 1 11.54843043 -4.261368734 23.7738876 0.951896413 0.685430152 0.88592778 0.028293981 0.863925898 289480.2868 0.005133247 0.039634797 5.48E-05 4.261368734 -0.266466261 TGSGSPFAGNS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 4 TGSGSPFAGNSPAR 14 0 M0QY97;Q9UPT8 M0QY97 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 0 T(0.022)GS(0.001)GS(0.138)PFAGNS(0.839)PAR;TGSGSPFAGNS(1)PAR;TGSGSPFAGNS(1)PAR;T(0.011)GS(0.017)GS(0.008)PFAGNS(0.965)PAR ;;; 188.19 1.22E-05 171317000 6676.3 5277 6265 5751.9 6967.5 7233.8 5461 4700.17 6235.1 5050.9 TRUE FALSE FALSE 6147.86381 5733.120366 6497.186411 5728.100162 6884.417113 5733.428338 5614.220962 6133.230196 5551.125129 5226.418399 1.176305328 1.096950135 1.243143184 1.095989591 1.31723421 1.097009061 1.074200444 1.173505397 1.062127963 1 12.35160691 -9.273471198 0.755363268 0.987457846 1.160387283 0.311329194 0.074094898 0.616940063 0.558976019 0.066993425 0.01381727 5.33E-10 9.273471198 0.172929438 TGSGSPFAGNS(ph)PAREGEQDAASLK ddPTM_HeLa_Curcumin_4h_R1 2 TGSGSPFAGNSPAREGEQDAASLK 24 1 M0QY97;Q9UPT8 M0QY97 ZC3H4 Zinc finger CCCH domain-containing protein 4 1 0 T(0.001)GS(0.001)GS(0.006)PFAGNS(0.991)PAREGEQDAAS(0.001)LK;T(0.002)GS(0.005)GS(0.004)PFAGNS(0.986)PAREGEQDAAS(0.003)LK ; 55.302 0.0041539 40968000 3767.3 2658.75 3629.6 3490.6 3393.1 4113.6 2433.83 2792.3 3659.5 3291.9 TRUE FALSE FALSE 3469.11423 2888.560503 3764.116169 3476.156822 3352.639499 3260.39299 2502.116719 3643.659416 3258.062006 3406.29328 1.018442613 0.848006987 1.105047587 1.020510137 0.984248631 0.957167432 0.734557043 1.069684586 0.956483115 1 11.73398694 -4.992570163 24.99827887 1.00222941 0.888056171 0.104071986 0.096914938 198.8745625 669115.3756 0.011789909 0.035265299 1.02E-05 4.992570163 -0.114173239 TGSNIS(ph)GASSDISLDEQYK ddPTM_HeLa_Curcumin_4h_R1 1 TGSNISGASSDISLDEQYK 19 0 P22059 P22059 OSBP Oxysterol-binding protein 1 1 0 TGSNIS(1)GASSDISLDEQYK 224.99 5.37E-20 10049000 2625.7 2236.1 3195.5 3020.1 2464.6 2023.3 1472.3 474.28 1746.6 2181.5 TRUE FALSE FALSE 2417.873074 2429.37852 3313.928041 3007.603626 2435.211255 1603.644773 1513.608776 618.8857887 1555.00235 2257.306963 1.071131713 1.076228692 1.46808923 1.332385748 1.078812627 0.710423881 0.670537415 0.274169973 0.688875007 1 11.1403869 -4.766466467 1.453975566 1.095520406 0.30443465 0.624900661 0.205248715 0.247114149 0.828581138 0.026982242 0.215614693 1.71E-05 4.766466467 -0.791085756 TGSPGS(ph)PGAGGVQSTAK ddPTM_HeLa_Curcumin_4h_R1 2 TGSPGSPGAGGVQSTAK 17 0 O43237;O43237-2;J3KRZ2;J3KRI4 O43237 DYNC1LI2 Cytoplasmic dynein 1 light intermediate chain 2 1 0 TGSPGS(1)PGAGGVQSTAK;TGS(0.002)PGS(0.998)PGAGGVQSTAK ; 220.78 8.46E-16 28128200 4419.8 3995.8 4702.5 4755 4995.6 5939.1 4913.6 2624.4 4282.1 3721.2 TRUE FALSE FALSE 4069.968166 4341.179147 4876.778787 4735.32507 4936.030733 4707.263713 5051.462392 3424.567479 3812.364343 3850.511423 1.056994181 1.127429235 1.266527547 1.229791202 1.281915619 1.222503505 1.311893885 0.889379904 0.990092984 1 11.91083436 -7.164683995 2.163213398 1.023837075 1.211228399 0.347375403 0.112067862 0.23495844 2.106494249 0.018600665 0.022860565 6.84E-08 7.164683995 0.187391325 TGSQGQCTQVR ddPTM_HeLa_Curcumin_4h_R1 1 TGSQGQCTQVR 11 0 P62857 P62857 RPS28 40S ribosomal protein S28 0 0 158.47 1.56E-07 1504000 302.87 233.99 299.29 256.5 337.1 246.87 237.36 286.12 317.83 271.56 FALSE FALSE TRUE 278.8975199 254.215053 310.3819507 255.438671 333.0803027 195.6663792 244.0196828 373.3566709 282.9648442 280.9966898 0.992529557 0.904690561 1.104575114 0.909045125 1.185353119 0.696329837 0.868407678 1.328687079 1.007004191 1 8.134409325 TGSS(ph)SPPGGPPKPGSQLDSMLGSLQSDLNK ddPTM_HeLa_Curcumin_4h_R1 2 TGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 30 1 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-3;P49023-4 A0A1B0GTU4;P49023-4 PXN Paxillin 1 0 T(0.097)GS(0.097)S(0.269)S(0.269)PPGGPPKPGS(0.267)QLDS(0.001)MLGSLQSDLNK;T(0.096)GS(0.109)S(0.37)S(0.37)PPGGPPKPGS(0.048)QLDS(0.006)MLGSLQSDLNK ; 79.365 2.91E-06 1306570000 3367.9 2849.3 3304.4 3015.1 2827.8 3796.3 3026.4 3002.8 3298.2 2978.2 TRUE FALSE FALSE 3101.327161 3095.580796 3426.863971 3002.624315 2794.080332 3008.904587 3111.312639 3918.339897 2936.395712 3081.692228 1.006371478 1.004506799 1.112007208 0.974342696 0.906670792 0.976380626 1.009611735 1.27148969 0.952851711 1 11.58950707 -4.262002126 5.77433678 1.000357148 1.279799817 0.73600755 0.049805797 0.052293829 7.558951471 0.006588005 0.057284628 5.47E-05 4.262002126 0.279442668 TGSSSPPGGPPKPGSQLDS(ph)MLGSLQSDLNK ddPTM_HeLa_Curcumin_4h_R1 1 TGSSSPPGGPPKPGSQLDSMLGSLQSDLNK 30 1 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-3;P49023-4 A0A1B0GTU4;P49023-4 PXN Paxillin 1 0 T(0.034)GS(0.085)S(0.085)S(0.249)PPGGPPKPGS(0.093)QLDS(0.317)MLGS(0.119)LQS(0.019)DLNK 56.452 0.0063393 147130000 1029.1 714.57 954.01 919.08 1073.7 1170.3 750.87 1057 1111.1 914.16 TRUE FALSE FALSE 947.6456491 776.3342467 989.3664498 915.2770905 1060.896829 927.566588 771.9373913 1379.274434 989.2151098 945.926992 1.001816903 0.820712648 1.045922633 0.967598026 1.121541977 0.980590041 0.816064451 1.458119333 1.045762642 1 9.885585028 -4.248198545 24.96011016 0.987105983 1.458119645 0.714354375 0.090950917 843.0737925 1589239.445 0.011458514 0.294351933 5.65E-05 4.248198545 0.471013662 DGGRS(ph)SPGGQDEGGFMAQGK ddPTM_HeLa_Curcumin_4h_R1 1 DGGRSSPGGQDEGGFMAQGK 20 1 A0A1B0GTU4;F5GZ78;P49023;A0A1B0GV30 A0A1B0GTU4 PXN Paxillin 1 0 DGGRS(0.609)S(0.391)PGGQDEGGFMAQGK 103.25 0.00016835 151330000 4490.5 3420.7 3567.1 4236.8 3225.1 3902.1 2373.2 1663.8 5316.7 4371.1 TRUE FALSE FALSE 4135.072187 3716.370066 3699.299864 4219.269244 3186.642789 3092.760474 2439.785605 2171.084961 4733.471312 4522.9954 0.914233118 0.821661253 0.81788716 0.932848449 0.704542567 0.683785899 0.539418104 0.480010429 1.046534629 1 12.14306281 -4.080748571 0.331376769 0.984446449 3.32E-17 0.902054896 0.056405364 1.488071652 0.105882823 0.019389887 0.601398161 8.30E-05 4.080748571 -0.984446449 down TGTAEMSSILEER ddPTM_HeLa_Curcumin_4h_R1 2 TGTAEMSSILEER 13 0 P25705;P25705-3;K7ERX7;K7ESA0 P25705 ATP5A1 "ATP synthase subunit alpha, mitochondrial" 0 0 ; ; 152.54 0.00016143 4805600 1460.2 1017.62 1192.73 1423.05 1526.78 1463.19 1275.51 1024.81 1348.47 1166.44 FALSE FALSE TRUE 1344.623629 1105.578538 1236.933623 1417.161796 1508.574146 1159.7079 1311.297378 1337.269851 1200.546215 1206.973703 1.114045505 0.915992234 1.024822347 1.174144716 1.249881536 0.96083941 1.086434091 1.107952765 0.994674707 1 10.23717853 -6.287642877 24.29750213 1.040710339 1.113050711 0.246063199 0.084450911 834.5198663 773816.9187 0.013848234 0.021158267 5.16E-07 6.287642877 0.072340371 TGTITTFEHAHNMR ddPTM_HeLa_Curcumin_4h_R1 2 TGTITTFEHAHNMR 14 0 P13639 P13639 EEF2 Elongation factor 2 0 0 ; ; 76.522 0.0071112 13914100 6714 6247.7 5992.7 6191.7 6439.7 7346.5 5548.4 5158.9 7857 6993.1 FALSE FALSE TRUE 6182.579815 6787.723349 6214.794734 6166.080386 6362.910783 5822.753088 5704.073171 6731.824861 6995.106757 7236.109704 0.85440659 0.938034887 0.858858556 0.852126438 0.879327573 0.804680046 0.788278979 0.930309951 0.966694404 1 12.82099857 -11.82515464 0.244661223 1.343089938 0.839202519 0.537160714 0.044742025 10.28229047 0.27927556 1.774804563 0.029303521 1.50E-12 11.82515464 -0.503887419 TGTLQPWNS(ph)DSTLNSR ddPTM_HeLa_Curcumin_4h_R1 1 TGTLQPWNSDSTLNSR 16 0 Q9H0H5;F8VRD2;H0YIK5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 0 TGT(0.001)LQPWNS(0.356)DS(0.212)T(0.212)LNS(0.219)R 93.909 0.0072286 0 720.7 739.8 938.74 916.86 840.27 741.59 553.55 400.54 832.86 747.99 TRUE FALSE FALSE 663.6558345 803.7450155 973.5305302 913.0662763 830.250329 587.7758746 569.0811232 522.6628021 741.4973417 773.9825968 0.857455758 1.038453602 1.257819664 1.179698717 1.072698963 0.75941743 0.735263461 0.675290122 0.958028442 1 9.596157317 -5.158280747 5.170461965 0.991226091 0.716170575 0.595619381 0.117135969 0.173070711 7.011613673 0.020894783 0.054879351 6.95E-06 5.158280747 -0.275055516 TGVAVNKPAEFTVDAK ddPTM_HeLa_Curcumin_4h_R1 2 TGVAVNKPAEFTVDAK 16 1 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 162.64 0.00054526 19246100 11061.7 6588.3 10715.2 8591.9 10358.7 12818.5 9412.4 9627.4 9272.1 8800.6 FALSE FALSE TRUE 10186.15477 7157.763295 11112.31474 8556.348994 10235.17927 10159.79861 9676.486612 12562.74994 8254.973828 9106.420195 1.118568499 0.78601285 1.220272566 0.939595232 1.123952008 1.115674259 1.062600496 1.379548678 0.906500431 1 13.15266832 -1.604257223 1.160546574 1.045900243 199.9999992 0.419339377 0.121653689 620.1321314 1.780066681 0.015527632 327300.589 0.024873837 1.604257223 198.954099 TGVAVNKPAEFTVDAK(ac)HGGK ddPTM_HeLa_Curcumin_4h_R1 2 TGVAVNKPAEFTVDAKHGGK 20 2 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 1 ; TGVAVNKPAEFTVDAK(1)HGGK;TGVAVNKPAEFTVDAK(1)HGGK 81.639 0.0015656 28151000 9992.9 5882.9 9571 8019.7 9775.8 12353.4 9523 9134.7 9561.8 8436.6 FALSE TRUE FALSE 9201.951421 6391.391662 9925.70968 7986.516606 9659.22997 9791.165588 9790.18975 11919.82798 8512.894462 8729.771222 1.054088496 0.732137361 1.136995395 0.914859783 1.106470001 1.121583297 1.121471514 1.365422721 0.97515665 1 13.09172813 -2.118754912 0.66594799 1.005788583 7.660708839 0.536573241 0.107166257 25.69901948 0.722250689 0.016910404 230.2232619 0.007607555 2.118754912 6.654920256 TGVELGKPTHFTVNAK ddPTM_HeLa_Curcumin_4h_R1 2 TGVELGKPTHFTVNAK 16 1 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 82.483 0.0035096 16765800 6403.8 5998.4 4438.8 5341.1 9520.2 16101.5 8572.5 6342.5 10148.8 6945.6 FALSE FALSE TRUE 5896.932473 6516.874968 4603.305833 5318.999943 9406.677833 12761.8674 8813.021278 8276.299053 9035.502031 7186.959083 0.820504528 0.906763889 0.640508145 0.740090472 1.308853678 1.775697795 1.226251767 1.151571751 1.257207941 1 12.81116576 -5.677399743 5.994696808 0.879135971 1.393873548 0.529856156 0.217547663 0.10510545 5.922305027 0.027897129 0.056110574 2.10E-06 5.677399743 0.514737576 LNRSDS(ph)DSSTLSK ddPTM_HeLa_Curcumin_4h_R1 2 LNRSDSDSSTLSK 13 1 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 0 LNRS(0.001)DS(0.91)DS(0.08)S(0.003)T(0.007)LSK;LNRSDS(0.84)DS(0.156)S(0.004)TLSK ; 194.01 5.01E-05 24011900 6973.1 5378.3 5141.8 6261.4 4707.7 6513.9 4291.3 1913.95 7500.7 6671.1 TRUE FALSE FALSE 6421.171777 5843.176287 5332.359631 6235.491986 4651.563752 5162.843713 4411.702329 2497.504544 6677.891976 6902.920228 0.93021092 0.846478895 0.772478814 0.90331219 0.673854485 0.747921683 0.639106665 0.361804057 0.967401006 1 12.7529911 -4.080104374 0.333152539 0.988643783 3.18E-16 0.85108556 0.070378688 1.878867964 0.134819187 0.02449207 0.76654652 8.32E-05 4.080104374 -0.988643783 down TGVTS(ph)TSDS(ph)EEEGDDQEGEKKR ddPTM_HeLa_Curcumin_4h_R1 1 TGVTSTSDSEEEGDDQEGEKKR 22 2 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 2 0 T(0.006)GVT(0.058)S(0.519)T(0.204)S(0.419)DS(0.794)EEEGDDQEGEKKR 52.298 0.0094334 226300000 4244.5 3483.3 3689.9 4614.2 3467.3 4874.8 3495.6 3751.7 5123.4 4488.5 TRUE FALSE FALSE 3908.543346 3784.380931 3826.65094 4595.107663 3425.954712 3863.71153 3593.677128 4895.576059 4561.375838 4644.475041 0.841546851 0.814813493 0.823914631 0.98937073 0.737640892 0.831894131 0.773753136 1.054064456 0.982107945 1 12.18129982 -9.173947206 0.836452217 1.003771891 0.852173633 0.2510791 0.090593786 0.661042155 0.803834857 0.063842403 0.016582971 6.70E-10 9.173947206 -0.151598258 TGVTST(ph)SDS(ph)EEEGDDQEGEKK ddPTM_HeLa_Curcumin_4h_R1 2 TGVTSTSDSEEEGDDQEGEKK 21 1 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 2 0 T(0.008)GVT(0.133)S(0.147)T(0.572)S(0.208)DS(0.932)EEEGDDQEGEKK;T(0.029)GVT(0.252)S(0.254)T(0.507)S(0.303)DS(0.655)EEEGDDQEGEKK ; 65.854 0.0033456 42330000 6030.8 5126.2 5413.2 5568 6096.7 6694.7 5788.6 5889.4 6122.9 5366 TRUE FALSE FALSE 5553.455816 5569.285886 5613.817954 5544.961091 6024.000834 5306.143755 5951.012537 7685.050949 5451.233189 5552.468101 1.000177888 1.003028885 1.011049114 0.998647987 1.084923087 0.955636963 1.071777888 1.384078361 0.981767583 1 12.43891348 -4.275726776 3.183960521 1.004652454 1.433565473 0.929499744 0.031213666 0.050149525 0.799243867 0.003777676 0.052283441 5.30E-05 4.275726776 0.428913019 TGVTSTS(ph)DS(ph)EEEGDDQEGEK ddPTM_HeLa_Curcumin_4h_R1 2 TGVTSTSDSEEEGDDQEGEK 20 0 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 2 0 T(0.014)GVT(0.018)S(0.042)T(0.19)S(0.82)DS(0.917)EEEGDDQEGEK;T(0.002)GVT(0.007)S(0.028)T(0.162)S(0.849)DS(0.953)EEEGDDQEGEK ; 114.19 0.0003535 64362000 5394.4 4371.9 5128.3 5292.2 6186.8 5994.3 4995.2 4826.1 4769.7 4874.2 TRUE FALSE FALSE 4967.427548 4749.787555 5318.359309 5270.302279 6113.026451 4751.01461 5135.351868 6297.555673 4246.475843 5043.578087 0.984901485 0.941749582 1.054481405 1.044953045 1.212041599 0.941992873 1.018196165 1.248628566 0.841956994 1 12.30023188 -6.465494553 2.746657367 0.989055893 1.087470855 0.308221491 0.09689412 0.304160045 4.54086082 0.012846521 0.019973869 3.42E-07 6.465494553 0.098414962 TGVTSTS(ph)DS(ph)EEEGDDQEGEKK ddPTM_HeLa_Curcumin_4h_R1 2 TGVTSTSDSEEEGDDQEGEKK 21 1 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 2 0 T(0.029)GVT(0.139)S(0.128)T(0.229)S(0.713)DS(0.762)EEEGDDQEGEKK;T(0.008)GVT(0.033)S(0.07)T(0.219)S(0.758)DS(0.913)EEEGDDQEGEKK ; 76.161 0.00073947 326320000 15472.8 13030.3 15658.2 15883.6 15248.3 17988.9 16232.6 14241.2 16085.7 14879 TRUE FALSE FALSE 14248.11155 14156.58107 16238.50667 15817.87787 15066.47398 14257.79936 16688.04307 18583.27632 14321.13895 15396.04414 0.92543977 0.919494705 1.054719415 1.027398839 0.978593842 0.92606901 1.08391759 1.207016306 0.930183028 1 13.91027209 -4.485758821 3.080796026 0.970773183 1.203178492 0.733238444 0.045086455 0.113228747 1.953376962 0.006848618 0.048378508 3.27E-05 4.485758821 0.232405309 TGVTSTS(ph)DS(ph)EEEGDDQEGEKKR ddPTM_HeLa_Curcumin_4h_R1 3 TGVTSTSDSEEEGDDQEGEKKR 22 2 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 2 0 T(0.005)GVT(0.029)S(0.097)T(0.244)S(0.69)DS(0.934)EEEGDDQEGEKKR;T(0.002)GVT(0.019)S(0.108)T(0.301)S(0.697)DS(0.874)EEEGDDQEGEKKR;T(0.001)GVT(0.006)S(0.029)T(0.251)S(0.777)DS(0.936)EEEGDDQEGEKKR ;; 60.938 0.0064991 553528000 10766.8 9093.9 9504.4 10931.4 9664.8 12906.9 9436.7 8802.7 12261.3 10821.9 TRUE FALSE FALSE 9914.596419 9879.936194 9856.641425 10886.16876 9549.553572 10229.86345 9701.468404 11486.60271 10916.26607 11197.96022 0.885393074 0.882297847 0.880217578 0.972156406 0.852794025 0.913547043 0.86636032 1.025776345 0.974844155 1 13.45094834 -9.311927233 1.007236621 1.000678204 0.905687479 0.267957765 0.050377763 0.472862718 0.849760351 0.032368 0.008376964 4.88E-10 9.311927233 -0.094990725 TGVTSTS(ph)DS(ph)EEEGDDQEGEKKRK ddPTM_HeLa_Curcumin_4h_R1 1 TGVTSTSDSEEEGDDQEGEKKRK 23 3 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 2 0 T(0.007)GVT(0.054)S(0.161)T(0.477)S(0.564)DS(0.737)EEEGDDQEGEKKRK 49.066 0.014715 14294000 4912.4 2740.8 2990.2 4125 2441.8 4260.2 3259.2 3405.9 6056.1 4876.7 TRUE FALSE FALSE 4523.578356 2977.702539 3101.019442 4107.931843 2412.68313 3376.586498 3350.64438 4444.343231 5391.760982 5046.164962 0.896438858 0.590092191 0.614529938 0.814070066 0.478122128 0.669139143 0.663998186 0.88073681 1.068486865 1 12.30097165 -7.404861432 3.972656332 0.956282387 0.668598339 0.620091397 0.11285856 0.114803321 3.052525337 0.018605701 0.021018982 3.94E-08 7.404861432 -0.287684048 TGVTSTS(ph)DSEEEGDDQEGEKKR ddPTM_HeLa_Curcumin_4h_R1 1 TGVTSTSDSEEEGDDQEGEKKR 22 2 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 1 0 T(0.008)GVT(0.094)S(0.094)T(0.105)S(0.391)DS(0.309)EEEGDDQEGEKKR 51.301 0.018512 2772400 531.25 434.34 452.16 389.97 607.09 461.54 410.7 442.3 500.06 576.35 TRUE FALSE FALSE 489.2010019 471.8824142 468.9174474 388.3564075 599.8508483 365.8114014 422.2231367 577.1552339 445.2046691 596.3781196 0.820286637 0.791247027 0.786275405 0.651191576 1.005823032 0.613388368 0.707978919 0.967767285 0.74651409 1 9.220083518 -8.796909181 0.575565119 1.01278914 0.778932015 0 0.140187316 0.816278341 0.491934343 0.095239952 0.028000429 1.60E-09 8.796909181 -0.233857125 TGVTSTSDS(ph)EEEGDDQEGEKKR ddPTM_HeLa_Curcumin_4h_R1 1 TGVTSTSDSEEEGDDQEGEKKR 22 2 O75475;O75475-3;O75475-2 O75475 PSIP1 PC4 and SFRS1-interacting protein 1 0 T(0.001)GVT(0.007)S(0.021)T(0.025)S(0.088)DS(0.859)EEEGDDQEGEKKR 78.122 0.00071721 3326600 946.18 775.9 682.82 613.78 687.37 780.51 701.68 744.29 948.76 661.49 TRUE FALSE FALSE 871.2888546 842.9653387 708.1259099 611.240341 679.1735617 618.6234278 721.3672523 971.2205947 844.6834017 684.4767283 1.272926922 1.231547113 1.034550746 0.893003832 0.992252232 0.9037903 1.053895951 1.418924201 1.234057152 1 9.418857681 -6.676691704 13.623859 1.140177465 1.033203418 0.124614124 0.155474868 1.74883528 275.659946 0.027103485 0.038329951 2.11E-07 6.676691704 -0.106974046 SFS(ph)SSAEEHS ddPTM_HeLa_Curcumin_4h_R1 1 SFSSSAEEHS 10 0 Q96EQ0 Q96EQ0 SGTB Small glutamine-rich tetratricopeptide repeat-containing protein beta 1 0 SFS(0.998)S(0.001)S(0.001)AEEHS 200.56 3.02E-06 52984000 4143.1 3794.9 3551.8 3723.4 4740.4 6726.4 4644 6992.3 5178 4149.9 TRUE FALSE FALSE 3815.169263 4122.914246 3683.432832 3707.993557 4683.873826 5331.268818 4774.298141 9124.220081 4609.986355 4294.108716 0.888465923 0.960132712 0.857787512 0.863507145 1.090767406 1.241530937 1.111825167 2.124822794 1.073560699 1 12.068143 -1.612335248 0.935730314 0.943856356 199.99993 0.902886925 0.110424736 56.54477939 0.368180641 0.015672817 23732.6009 0.024415451 1.612335248 199.0560737 up TGYLEQGLLVK ddPTM_HeLa_Curcumin_4h_R1 2 TGYLEQGLLVK 11 0 P29973;P29973-2 P29973 CNGA1 cGMP-gated cation channel alpha-1 0 0 ; ; 99.442 0.011058 4897600 1151.15 1073.61 923.33 2068.04 1393.07 1275.9 904.15 997.99 1160.36 1070.47 FALSE FALSE TRUE 1060.035263 1166.408064 957.549422 2059.482998 1376.45855 1011.263958 929.5180156 1302.272557 1033.071411 1107.668753 0.956996629 1.053029673 0.864472722 1.859295022 1.242662616 0.912966042 0.839166053 1.175687726 0.932653745 1 10.11331079 TGYTLDVTTGQR ddPTM_HeLa_Curcumin_4h_R1 2 TGYTLDVTTGQR 12 0 O60506-4;O60506-3;O60506-2;O60506;B7Z645;F6UXX1;O43390;O43390-4;O43390-2 O60506-4;O43390 SYNCRIP;HNRNPR Heterogeneous nuclear ribonucleoprotein Q;Heterogeneous nuclear ribonucleoprotein R 0 0 ; ; 184.71 1.09E-09 10241900 5478.9 3903.4 4248.1 4585.5 4952.5 6173.6 5068.6 4291.9 4862.4 4339.5 FALSE FALSE TRUE 5045.239284 4240.792503 4405.538323 4566.526416 4893.444672 4893.125769 5210.811275 5600.480553 4329.006885 4490.297302 1.123586913 0.944434682 0.981123972 1.016976407 1.089781888 1.089710868 1.160460193 1.247240478 0.964080237 1 12.13259525 -4.483757277 1.146268909 1.042566695 1.299350544 0.646414773 0.054874547 0.688275835 0.951262897 0.009479336 0.191397457 3.28E-05 4.483757277 0.256783849 THAVS(ph)VSETDDYAEIIDEEDTYTMPSTR ddPTM_HeLa_Curcumin_4h_R1 1 THAVSVSETDDYAEIIDEEDTYTMPSTR 28 0 Q05397-5;Q05397;Q05397-7;Q05397-2;E7ESA6;H0YBP1;Q05397-3;Q05397-4;H0YB33;H0YB99 Q05397-5 PTK2 Focal adhesion kinase 1 1 0 T(0.062)HAVS(0.552)VS(0.32)ET(0.066)DDYAEIIDEEDTYTMPSTR 95.543 9.30E-08 5185400 438.32 365.02 371.04 267.65 369.7 578.21 215.5 253.22 380.69 339.55 TRUE FALSE FALSE 403.6265095 396.5707023 384.7910688 266.5425352 365.291569 458.2827282 221.54635 330.4256123 338.9292594 351.3493372 1.148789728 1.1287077 1.095180859 0.758625411 1.039681964 1.304350627 0.630558611 0.940447518 0.964650345 1 8.456762367 THAVSVSETDDY(ph)AEIIDEEDTYTMPSTR ddPTM_HeLa_Curcumin_4h_R1 1 THAVSVSETDDYAEIIDEEDTYTMPSTR 28 0 Q05397-5;Q05397;Q05397-7;Q05397-2;E7ESA6;H0YBP1;Q05397-3;Q05397-4;H0YB33;H0YB99 Q05397-5 PTK2 Focal adhesion kinase 1 1 0 THAVSVSET(0.001)DDY(0.999)AEIIDEEDTYTMPSTR 131.75 2.40E-09 9280500 984.07 801.98 657.35 1078.7 883.95 1288.9 926.01 483.92 1108.9 1105.9 TRUE FALSE FALSE 906.1798211 871.2995776 681.7119693 1074.236625 873.4094736 1021.567611 951.9913484 631.4649803 987.2564443 1144.329943 0.791886839 0.761405907 0.595730256 0.938747284 0.76324969 0.89272121 0.831920334 0.551820726 0.862737579 1 10.16028737 -8.934205921 0.703846487 1.005941114 0.770755394 0.201978158 0.119524295 0.617646691 0.5520403 0.080548099 0.023820348 1.16E-09 8.934205921 -0.23518572 THCVGDSQSSASS(ph)PPATSK ddPTM_HeLa_Curcumin_4h_R1 1 THCVGDSQSSASSPPATSK 19 0 Q9H4Z2-2;Q9H4Z2 Q9H4Z2-2 ZNF335 Zinc finger protein 335 1 0 THCVGDSQSS(0.001)AS(0.318)S(0.681)PPATSK 124.66 8.00E-05 5212500 796.95 753.95 951.65 673.4 1151.9 1662.7 1028.9 608.15 1148.5 701.44 TRUE FALSE FALSE 733.8705666 819.1180785 986.9189862 670.6136492 1138.164345 1317.837278 1057.768165 793.5721354 1022.512423 725.8149878 1.011098667 1.128549413 1.359739056 0.923945717 1.568119099 1.815665562 1.457352332 1.093353194 1.408778326 1 9.503458038 -6.22841262 1.007920685 1.00960074 1.481849905 0.142924363 0.255135597 0.356664354 0.716279896 0.039448075 0.085435994 5.91E-07 6.22841262 0.472249166 THEAQIQEMR ddPTM_HeLa_Curcumin_4h_R1 5 THEAQIQEMR 10 0 P35579 P35579 MYH9 Myosin-9 0 0 ;;;; ;;;; 135.8 0.00018851 134271300 3171.04 2580.93 2593.24 3174.3 3099.89 2940.87 2701.49 2792.11 2920.49 2719.44 FALSE FALSE TRUE 2920.048838 2804.014089 2689.347756 3161.165588 3062.925836 2330.900412 2777.286539 3643.411486 2600.119554 2813.940338 1.037708156 0.996472474 0.95572309 1.123394674 1.088482863 0.828340381 0.986974209 1.294772116 0.924013746 1 11.45837602 -4.258565332 24.66904736 1.010155387 1.294772241 0.553137055 0.079990727 124.7039104 1070310.336 0.010158136 0.09403418 5.51E-05 4.258565332 0.284616854 THILLFLPK ddPTM_HeLa_Curcumin_4h_R1 2 THILLFLPK 9 0 P07237;H7BZ94;I3L398;I3L312;I3L4M2 P07237 P4HB Protein disulfide-isomerase 0 0 ; ; 86.67 0.010275 0 1890.85 1020.84 1444.66 1286.23 1379.94 1565.31 1260.45 949.41 1403.43 1590.47 FALSE FALSE TRUE 1741.187227 1109.076861 1498.20037 1280.907921 1363.485117 1240.647061 1295.814835 1238.880738 1249.47724 1645.738714 1.057997368 0.673908228 0.910351296 0.778317913 0.828494283 0.753854212 0.787375799 0.752780941 0.759219692 1 10.68451959 -7.2743074 24.99955741 1.027387652 0.788986212 0.204327792 0.102857138 230.4770454 447762.1937 0.009417619 0.010805683 5.32E-08 7.2743074 -0.23840144 THINIVVIGHVDSGK ddPTM_HeLa_Curcumin_4h_R1 1 THINIVVIGHVDSGK 15 0 A0A2U3TZH3;Q05639;A0A2R8Y488;A0A2R8Y660;A0A2R8YDN5;Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A6PW80;Q5JR01 A0A2U3TZH3;Q5VTE0 EEF1A2;EEF1A1P5;EEF1A1 Elongation factor 1-alpha 2;Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 0 84.62 0.0043452 4179200 4538.5 4650.7 4173 4352.4 4803.3 8036.6 5543 4601.9 5500.4 4721.5 FALSE FALSE TRUE 4179.272936 5052.685785 4327.655051 4334.390922 4746.023785 6369.718569 5698.521662 6004.998125 4897.019881 4885.571774 0.855431694 1.03420562 0.885803188 0.887181915 0.971436713 1.303781597 1.166398106 1.229129036 1.002343248 1 12.2543117 -5.341005872 5.580730796 0.93231936 1.225679376 0.807666246 0.063532268 0.070676969 3.760920143 0.009839021 0.022421788 4.56E-06 5.341005872 0.293360016 THLGEQAGKDS(ph)S ddPTM_HeLa_Curcumin_4h_R1 1 THLGEQAGKDSS 12 1 Q5VV50;Q5VV52-3;Q5VV52 Q5VV50 ZNF691 Zinc finger protein 691 1 0 THLGEQAGKDS(0.564)S(0.436) 70.373 0.016022 5685300 3082.7 2730.8 2335.5 2753.6 2768 3318.3 3053.5 1389.2 2890.7 2813.9 TRUE FALSE FALSE 2838.701042 2966.838184 2422.055685 2742.206333 2734.993408 2630.047175 3139.172992 1812.760685 2573.597442 2911.682816 0.974934848 1.01894278 0.831840498 0.941794318 0.939317083 0.903273928 1.078130137 0.622581785 0.883886606 1 11.50763749 -4.250516515 24.91865524 0.972064868 0.622581576 0.661267941 0.069566657 597.3386355 1362699.841 0.008569323 0.170489887 5.62E-05 4.250516515 -0.349483292 THLMSEEEWR ddPTM_HeLa_Curcumin_4h_R1 1 THLMSEEEWR 10 0 P33552 P33552 CKS2 Cyclin-dependent kinases regulatory subunit 2 0 0 142.98 0.0050444 12397000 2640.3 2147.6 2382.8 2661.9 2635.1 3353.1 1908.1 1486.8 2647.8 2319.7 FALSE FALSE TRUE 2431.317469 2333.228974 2471.108664 2650.885763 2603.678154 2657.629263 1961.636151 1940.118476 2357.342964 2400.309402 1.012918362 0.972053425 1.02949589 1.104393359 1.084726057 1.107202788 0.817243039 0.808278497 0.982099625 1 11.22900467 -4.745943699 24.98330481 1.023514529 0.812760566 0.778687299 0.047325027 90.23944582 145488.3123 0.007098075 0.026364799 1.79E-05 4.745943699 -0.210753963 THNDIIHNENMR ddPTM_HeLa_Curcumin_4h_R1 7 THNDIIHNENMR 12 0 E7EQR4;P15311 E7EQR4 EZR Ezrin 0 0 ;;;;;; ;;;;;; 185.3 1.22E-05 46987300 5453.88 4114.11 4627.43 5369.21 4828.61 6350.22 4634.45 4603.64 6241 5204.84 FALSE FALSE TRUE 5022.199643 4469.715336 4798.926627 5346.993632 4771.031979 5033.11279 4764.480194 6007.268643 5556.377914 5385.707803 0.932505035 0.829921618 0.891048457 0.992811684 0.885869073 0.934531351 0.88465256 1.115409314 1.031689449 1 12.39492024 -8.878866648 1.042715215 0.994948694 0.928937585 0.147451702 0.074549556 0.770147732 1.650436607 0.030549734 0.013322524 1.32E-09 8.878866648 -0.066011109 THS(ph)DAS(ph)DDEAFTTSK ddPTM_HeLa_Curcumin_4h_R1 1 THSDASDDEAFTTSK 15 0 Q13017-2;Q13017;H0YK04 Q13017-2 ARHGAP5 Rho GTPase-activating protein 5 2 0 T(0.13)HS(0.879)DAS(0.992)DDEAFTTSK 103.99 0.0061444 19848000 7002.5 5875.7 5618 7202.4 6736.7 7622.8 5549.5 6215.2 7390.3 7648.9 TRUE FALSE FALSE 6448.244736 6383.569326 5826.208022 7172.598377 6656.369252 6041.745353 5705.204034 8110.185869 6579.60258 7914.698706 0.814717651 0.806546094 0.736125055 0.906237703 0.8410136 0.763357593 0.720836541 1.024699255 0.831314346 1 12.95031872 -9.123431745 0.79064117 1.005381267 0.820107198 0.002078106 0.098182582 0.536774683 0.582717059 0.060935642 0.015995501 7.53E-10 9.123431745 -0.185274069 LYSGS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 2 LYSGSPTR 8 0 H3BMH3;Q6PJI9-4;Q6PJI9-3;Q6PJI9 H3BMH3 WDR59 WD repeat-containing protein 59 1 0 LYS(0.014)GS(0.948)PT(0.038)R;LYS(0.01)GS(0.495)PT(0.495)R ; 102.06 0.013846 128450000 6804.1 5490.2 5943.9 5931.4 5756.9 6908.9 5227.3 1909.6 6143.2 5689.5 TRUE FALSE FALSE 6265.548305 5964.748424 6164.186163 5906.857438 5688.252727 5475.916261 5373.963969 2491.828249 5469.30633 5887.209702 1.064264503 1.013170708 1.047047154 1.00333736 0.966205217 0.930137797 0.912820205 0.423261337 0.929015035 1 12.5233683 -4.079235537 1.544584227 1.022414233 1.31E-19 0.928123878 0.046997544 0.264260123 0.410612677 0.005944196 0.465297727 8.33E-05 4.079235537 -1.022414233 down THS(ph)EGSLLQEPR ddPTM_HeLa_Curcumin_4h_R1 1 THSEGSLLQEPR 12 0 C9J582;P49796-1;P49796-4;P49796-6;P49796 C9J582 RGS3 Regulator of G-protein signaling 3 1 0 T(0.046)HS(0.953)EGS(0.001)LLQEPR 108.36 0.0028672 3996900 2010.3 1628.8 1492.6 1439.8 1952.3 2324.6 1339.8 1055.5 2191.1 1529.9 TRUE FALSE FALSE 1851.182634 1769.586214 1547.917069 1433.842489 1929.020098 1842.451756 1377.391182 1377.317091 1950.741812 1583.063911 1.16936696 1.117823609 0.977798217 0.905738852 1.21853583 1.163851784 0.870079327 0.870032525 1.232257143 1 10.62850379 -4.746277321 24.72953725 1.078924044 0.870055711 0.430185962 0.10312947 160.7100107 262114.9973 0.014198506 0.052691689 1.79E-05 4.746277321 -0.208868333 THS(ph)MIDS(ph)S(ph)LS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 THSMIDSSLSK 11 0 D6RFX5;P15514 D6RFX5 AREG Amphiregulin 4 0 T(0.003)HS(0.998)MIDS(1)S(0.999)LS(1)K 50.805 0.009268 0 1549.5 1176.7 1187 1476.6 1293.3 1093.6 838.42 688.8 1414.6 1423.8 TRUE FALSE FALSE 1426.85544 1278.408705 1230.991264 1470.49022 1277.878242 866.7750326 861.9438087 898.8119492 1259.421919 1473.276944 0.968490986 0.867731427 0.835546412 0.998108486 0.867371371 0.588331363 0.585052126 0.610076709 0.854843975 1 10.52481294 -5.35997742 3.15964421 0.962940908 0.589399715 0.832355274 0.064092009 0.06165318 1.171816532 0.009094585 0.022497205 4.37E-06 5.35997742 -0.373541193 THS(ph)QGGYGSQGYK ddPTM_HeLa_Curcumin_4h_R1 1 THSQGGYGSQGYK 13 0 K7ER00;Q9Y285-2;Q9Y285;K7ERS0;K7EPH2 K7ER00 FARSA Phenylalanine--tRNA ligase alpha subunit 1 0 T(0.003)HS(0.997)QGGYGSQGYK 104.9 0.0051397 6577800 1230.2 1203.4 892.04 1185.5 1331.2 1837.2 1251.3 1353.2 1296 1308.3 TRUE FALSE FALSE 1132.828372 1307.416534 925.0997871 1180.594715 1315.326309 1456.14401 1286.40811 1765.784451 1153.832042 1353.763328 0.836799423 0.965764478 0.683354149 0.87208354 0.971607284 1.075626722 0.950245943 1.304352404 0.852314447 1 10.40275983 -1.000000484 0.829570703 0.907483395 118.2406936 0.600113703 0.098794096 342.3931952 0.986002354 0.016766846 75740.50836 0.099999889 1.000000484 117.3332102 THSAGTS(ph)PTITHQK ddPTM_HeLa_Curcumin_4h_R1 1 THSAGTSPTITHQK 14 0 P35568 P35568 IRS1 Insulin receptor substrate 1 1 0 T(0.025)HS(0.077)AGT(0.147)S(0.746)PT(0.004)ITHQK 74.338 0.012566 2998500 2204.5 1925.5 1843.2 2283.8 1872.7 2602.9 1565.9 1045.6 2152.5 2109.4 TRUE FALSE FALSE 2030.011499 2091.93164 1911.510613 2274.350241 1850.369276 2063.029199 1609.83494 1364.398627 1916.376135 2182.701493 0.930045407 0.958413987 0.875754481 1.041988677 0.847742709 0.945172396 0.737542419 0.6250963 0.87798361 1 11.09189913 -4.387663495 1.109666185 0.960829508 0.489235639 0.734268527 0.06093184 0.414983065 0.472985132 0.007952701 0.215655752 4.10E-05 4.387663495 -0.471593869 THSDAS(ph)DDEAFTTSK ddPTM_HeLa_Curcumin_4h_R1 1 THSDASDDEAFTTSK 15 0 Q13017-2;Q13017;H0YK04 Q13017-2 ARHGAP5 Rho GTPase-activating protein 5 1 0 THSDAS(0.973)DDEAFT(0.027)TSK 265.64 1.80E-50 18468000 2014.1 1882 1567.9 2004.1 1808 2179.3 1487 751.24 2108.3 1744.1 TRUE FALSE FALSE 1854.68186 2044.671694 1626.007753 1995.807565 1786.440781 1727.288614 1528.721218 980.2896177 1877.024765 1804.707345 1.027691201 1.132965796 0.900981402 1.105889867 0.989878379 0.957101781 0.847074304 0.543184811 1.040071549 1 10.81754919 -4.048249222 1.206664623 1.020163901 0.124483831 0.857773629 0.060147274 0.550521446 0.475788533 0.008035889 0.693786341 8.95E-05 4.048249222 -0.89568007 THSLSNADGQYDPYT(ph)DSR ddPTM_HeLa_Curcumin_4h_R1 1 THSLSNADGQYDPYTDSR 18 0 A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-11;Q8IVL1;A0A0A0MTL4;Q8IVL1-4;Q8IVL1-3;Q8IVL1-2;Q8IVL1-5;E9PNV5;Q8IVL1-6 A0A0A0MTE8 NAV2 Neuron navigator 2 1 0 THSLSNADGQY(0.271)DPY(0.271)T(0.444)DS(0.015)R 122.18 0.00091829 3203900 1224.2 997.97 1237.8 1515.2 1274.2 1367 1062.3 1105.7 1464.4 1224.8 TRUE FALSE FALSE 1127.303278 1084.23008 1283.673957 1508.930504 1259.005997 1083.468791 1092.105279 1442.82284 1303.758984 1267.361709 0.889488195 0.855501687 1.012871028 1.190607617 0.993407003 0.854900999 0.86171554 1.138445978 1.028718932 1 10.30761262 THSTLT(ph)QRFPHSEMT(ph)T(ph)LMSR ddPTM_HeLa_Curcumin_4h_R1 1 THSTLTQRFPHSEMTTLMSR 20 1 Q8WXI7 Q8WXI7 MUC16 Mucin-16 3 0 T(0.156)HS(0.156)T(0.154)LT(0.535)QRFPHS(0.039)EMT(0.808)T(0.6)LMS(0.553)R 48.555 0.0082657 0 1456.6 1448.5 1459.1 1566.8 1648.6 2037.4 917.09 1528.4 1329.1 1180.2 TRUE FALSE FALSE 1341.308573 1573.701886 1513.17553 1560.316997 1628.941522 1614.820274 942.8210772 1994.402124 1183.301055 1221.211862 1.098342241 1.288639535 1.239076999 1.277679201 1.333872993 1.322309686 0.772037274 1.633133599 0.968956405 1 10.25409779 -7.508887128 1.834663692 1.034347638 1.2526889 0.236844014 0.199655848 0.368499252 2.465320173 0.035585175 0.038412899 3.10E-08 7.508887128 0.218341262 THTGEK(ac)PYR ddPTM_HeLa_Curcumin_4h_R1 2 THTGEKPYR 9 1 Q8N8E2-2;Q8N8E2;Q9UJW8-2;M0QZI7;F5H032;A0A1W2PQ54;G5E9B8;A0A0A0MP75;P17017;Q8WXB4;Q9NX65;Q9UJW8;Q9UJW8-4;Q9UJW8-3;O94892;A0A087X2B0;Q86UD4;Q99612;Q86TJ5;Q7Z3I7;Q15937;Q9BSK1;Q9NX65-2;Q499Z4;Q9BSK1-2;Q9NX65-3;Q9HCG1;E7EN86;P52747-2;P52747-3;P52747 Q8N8E2-2;E7EN86 ZNF513;ZNF180;ZNF160;ZNF79;ZNF14;ZNF606;ZSCAN32;ZNF432;ZNF329;KLF6;ZNF554;ZNF572;ZNF577;ZNF672;ZNF143 Zinc finger protein 513;Zinc finger protein 180;Zinc finger protein 14;Zinc finger protein 606;Zinc finger and SCAN domain-containing protein 32;Zinc finger protein 432;Zinc finger protein 329;Krueppel-like factor 6;Zinc finger protein 554;Zinc finger protein 572;Zinc finger protein 79;Zinc finger protein 577;Zinc finger protein 672;Zinc finger protein 160;Zinc finger protein 143 0 1 ; THTGEK(1)PYR;THTGEK(1)PYR 128.86 0.00087158 8775600 1892.77 1535.89 1374.97 1882.62 1947.65 1834.55 1965.26 1740.81 1906.25 1617.18 FALSE TRUE FALSE 1742.955257 1668.645488 1425.927598 1874.830217 1924.425546 1454.04365 2020.399906 2271.574955 1697.139144 1673.376885 1.041579619 0.997172546 0.852125789 1.120387305 1.150025176 0.868927773 1.207378879 1.357479583 1.014200184 1 10.7085467 -4.556372923 5.614516755 1.014999089 1.324968287 0.622810369 0.089351327 0.07140332 6.038253851 0.011727132 0.048261323 2.78E-05 4.556372923 0.309969198 THTTALAGRS(ph)PS(ph)PASGR ddPTM_HeLa_Curcumin_4h_R1 2 THTTALAGRSPSPASGR 17 1 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182;I3L1I8;Q9UQ35-3;A0A087X1W1 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 THTTALAGRS(0.997)PS(0.965)PAS(0.038)GR;THTTALAGRS(0.998)PS(0.997)PAS(0.004)GR ; 77.726 0.008007 52216000 5123.3 4362.3 3421.7 3870.2 6383.9 13744.8 4991.6 4384.9 6780.8 4040.2 TRUE FALSE FALSE 4717.785399 4739.357774 3548.511212 3854.186138 6307.776162 10893.97354 5131.650862 5721.835824 6036.963205 4180.596649 1.128495714 1.133655832 0.84880497 0.921922506 1.508821991 2.605841811 1.227492459 1.368664883 1.444043449 1 12.02949314 -5.61950818 5.243438237 1.04346491 1.739594739 0.388747207 0.37246706 0.136771191 6.00723273 0.049473522 0.100519079 2.40E-06 5.61950818 0.69612983 THYDPPRK ddPTM_HeLa_Curcumin_4h_R1 1 THYDPPRK 8 1 P31943;G8JLB6;E9PCY7;D6RBM0;E5RGV0;H0YB39;H0YBD7;E7EN40;P55795 P31943;P55795 HNRNPH1;HNRNPH2 "Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2" 0 0 60.972 0.016358 4158100 1240.6 2167.5 1213.5 1204.3 1311.5 1558.8 1257.1 1179.1 1224.3 1449.8 FALSE FALSE TRUE 1142.405201 2354.849042 1258.473378 1199.316926 1295.861219 1235.487309 1292.370843 1538.602162 1089.997353 1500.180442 0.761511861 1.569710533 0.838881339 0.799448448 0.863803568 0.823559136 0.861476931 1.025611399 0.726577499 1 10.55092032 TIAATPIQTLPQSQST(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 TIAATPIQTLPQSQSTPK 18 0 P14859-6;P14859-2;P14859;P14859-3;P14859-5;P14859-4;A0A0C4DG88 P14859-6 POU2F1 "POU domain, class 2, transcription factor 1;POU domain protein" 1 0 TIAATPIQTLPQSQS(0.209)T(0.791)PK;TIAATPIQTLPQSQS(0.169)T(0.831)PK ; 218.36 1.27E-16 51002000 11723.4 8703.1 9810.9 9974.9 9258.1 13915.2 13497.3 8094.8 12733.4 8772.5 TRUE FALSE FALSE 10795.48052 9455.357184 10174.50058 9933.626507 9147.703204 11029.03066 13875.99791 10562.86726 11336.57788 9077.343722 1.189277486 1.041643621 1.120867612 1.094331867 1.007751109 1.215006394 1.528640794 1.163651788 1.248887144 1 13.14805447 -4.998793284 24.98615316 1.086673662 1.352565675 0.442810138 0.109785397 22.51833554 466212.4461 0.013891432 0.041205691 1.00E-05 4.998793284 0.265892014 TIAMDGTEGLVR ddPTM_HeLa_Curcumin_4h_R1 2 TIAMDGTEGLVR 12 0 P06576;H0YH81;F8W079 P06576 ATP5B "ATP synthase subunit beta, mitochondrial;ATP synthase subunit beta" 0 0 ; ; 104.22 0.0053271 9820700 2311.2 1849.64 1981.38 2305.6 2573.7 4002.1 3007.3 2261.1 2955.9 2130.1 FALSE FALSE TRUE 2128.266081 2009.51464 2054.811686 2296.060038 2543.010308 3172.019347 3091.676744 2950.498981 2631.645165 2204.120816 0.965585038 0.911708027 0.932259099 1.041712424 1.153752684 1.439131341 1.402680253 1.338628518 1.193965932 1 11.10598759 -5.528451306 2.240355681 0.974817368 1.396506744 0.816867028 0.080737666 0.04604935 0.459344951 0.00651825 0.016021902 2.96E-06 5.528451306 0.421689376 TIAPALVSK ddPTM_HeLa_Curcumin_4h_R1 1 TIAPALVSK 9 0 P06733;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8Y6I8 P06733 ENO1 Alpha-enolase;Enolase 0 0 119.21 0.0014129 38565000 8723.7 6041.8 7513.2 7165.6 7491.8 10073 9286.4 9463.8 7465.8 6895.4 FALSE FALSE TRUE 8033.20994 6564.02627 7791.645801 7135.950646 7402.465178 7983.746254 9546.951391 12349.26905 6646.820419 7135.014637 1.125885559 0.919973764 1.092029407 1.000131185 1.037484232 1.118953031 1.338042299 1.730797999 0.931577685 1 12.80070067 -4.317029672 1.513571773 1.046148891 1.951961638 0.920011605 0.065210326 0.18809031 0.424769285 0.009027461 0.245255356 4.82E-05 4.317029672 0.905812747 TIAPALVSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 TIAPALVSKK 10 1 P06733;K7EM90;A0A2R8YEM5;A0A2R8Y879;K7ERS8;A0A2R8Y6I8 P06733 ENO1 Alpha-enolase;Enolase 0 1 ; TIAPALVSK(1)K;TIAPALVSK(1)K 161.17 1.70E-09 11835200 8966.3 5851.7 7758.4 6476.6 8338.6 12462.7 9727.5 10901 8965.4 6899.8 FALSE TRUE FALSE 8256.607894 6357.494873 8045.933129 6449.801545 8239.167641 9877.795536 10000.42747 14224.66472 7981.91805 7139.567536 1.156457706 0.890459379 1.126949649 0.903388267 1.154014945 1.383528552 1.400704933 1.992370637 1.117983409 1 12.80162097 -3.556086475 0.777871038 1.053187602 4.017710258 0.883724701 0.104551616 1.555213175 0.310385506 0.017216817 5.19379459 0.000277916 3.556086475 2.964522656 TIAPQNAPRDES(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 TIAPQNAPRDESR 13 1 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 TIAPQNAPRDES(1)R 75.911 0.011898 8153300 1951.5 2077.9 1924.3 2555.4 1509.6 1824.9 1521.4 1311.5 2550.7 2609 TRUE FALSE FALSE 1797.036716 2257.504417 1995.616251 2544.826432 1491.599006 1446.395169 1564.086389 1711.370313 2270.894592 2699.662556 0.665652347 0.836217257 0.739209516 0.942646119 0.552513129 0.535768875 0.579363664 0.633920083 0.841177201 1 11.39856337 -13.52287875 0.128255322 2.092788116 0.520175299 0.44409341 0.117194595 48.72168699 0.444615276 13.78274117 0.458152006 3.00E-14 13.52287875 -1.572612817 TIAQDYGVLK ddPTM_HeLa_Curcumin_4h_R1 2 TIAQDYGVLK 10 0 A0A0A0MSI0;Q06830 A0A0A0MSI0 PRDX1 Peroxiredoxin-1 0 0 ; ; 185.29 4.54E-16 27023000 8728.8 6542 7742.7 6048.5 7187.5 9885.1 7319.4 6756.4 8156.3 7286.4 FALSE FALSE TRUE 8037.906269 7107.461329 8029.651273 6023.47291 7101.793757 7834.818832 7524.762665 8816.395257 7261.574296 7539.601858 1.066091608 0.942683906 1.064996723 0.798911272 0.941932199 1.039155512 0.998031833 1.169344937 0.963124371 1 12.88027263 -4.259755534 23.75610844 1.00557438 1.169345042 0.301594835 0.07805523 77.42800831 1092166.464 0.011060686 0.093753051 5.50E-05 4.259755534 0.163770662 TIAS(ph)DSEEEAGK ddPTM_HeLa_Curcumin_4h_R1 1 TIASDSEEEAGK 12 0 Q96ST2-3;Q96ST2;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 0 T(0.115)IAS(0.831)DS(0.054)EEEAGK 104.81 0.0071241 5764000 1963.1 1896.5 1682.2 1428.7 2136.3 2156.6 1576.2 1084.1 1566.2 1387.6 TRUE FALSE FALSE 1807.718564 2060.425009 1744.543812 1422.788418 2110.826018 1709.29685 1620.42393 1414.637099 1394.391778 1435.818997 1.259015633 1.435017237 1.215016528 0.990924637 1.470119857 1.190468196 1.128571173 0.985247516 0.971147325 1 10.48765818 -9.267865053 1.067244554 1.003501186 1.216156246 0.25310648 0.151360891 0.608289676 1.271689822 0.093144927 0.027043972 5.40E-10 9.267865053 0.212655061 RPISDDDCPS(ph)ASK ddPTM_HeLa_Curcumin_4h_R1 2 RPISDDDCPSASK 13 1 Q96PU4 Q96PU4 UHRF2 E3 ubiquitin-protein ligase UHRF2 1 0 RPIS(0.114)DDDCPS(0.878)AS(0.007)K;RPIS(0.355)DDDCPS(0.638)AS(0.006)K ; 180.56 0.00022636 57674000 7689.9 6330 7156.4 6990.5 6596.8 7210.1 5868.1 2078.9 7669.4 7215.1 TRUE FALSE FALSE 7081.236301 6877.136994 7421.622479 6961.575163 6518.137469 5714.643985 6032.743093 2712.74704 6828.086008 7465.824188 0.948486881 0.921149068 0.99407946 0.932459028 0.873063349 0.765440471 0.808047838 0.363355334 0.914578998 1 12.86608582 -4.07893406 0.819949536 0.969023044 1.84E-22 0.882965638 0.060737782 0.651029397 0.260161868 0.008879585 0.61189068 8.34E-05 4.07893406 -0.969023044 down TIDDLEDKLK ddPTM_HeLa_Curcumin_4h_R1 3 TIDDLEDKLK 10 1 A0A087WWU8;P06753-2;P06753-5;P06753-7;J3KN67 A0A087WWU8;J3KN67 TPM3 Tropomyosin alpha-3 chain 0 0 ;; ;; 123.75 0.0033781 104329900 9034 7049.3 7079.6 8342.4 7494.5 10355 7114.4 6724.6 9128.5 8052.8 FALSE FALSE TRUE 8318.949367 7658.610081 7341.976204 8307.881359 7405.132982 8207.256275 7314.010917 8774.899584 8127.126388 8332.634201 0.998357682 0.919110319 0.881111066 0.99702941 0.888690515 0.984953387 0.87775495 1.053076299 0.975336993 1 13.02455693 -7.275733685 23.08822773 0.999224468 0.939796816 0.136591039 0.053899803 293.7687206 474495.4951 0.008034932 0.009216511 5.30E-08 7.275733685 -0.059427653 TIDDLEEK ddPTM_HeLa_Curcumin_4h_R1 2 TIDDLEEK 8 0 P67936;A0A2R8YE05;P67936-2;K7ENT6;A0A5F9UN72;K7EPB9 P67936 TPM4 Tropomyosin alpha-4 chain 0 0 ; ; 133.86 0.0012886 41299000 11089.4 8896.4 9689.6 10238.2 10016 11684 11132.3 9735.4 11273.2 9092.3 FALSE FALSE TRUE 10211.66229 9665.365174 10048.7051 10195.83704 9896.565742 9260.606694 11444.64238 12703.67864 10036.55816 9408.256748 1.085393667 1.027327956 1.06807301 1.083711607 1.051902176 0.984306332 1.216446647 1.350269129 1.066781916 1 13.19971172 -4.559332013 3.654619207 1.043303841 1.332015392 0.893944948 0.034053414 0.054334491 1.471251196 0.005630489 0.02870345 2.76E-05 4.559332013 0.288711551 TIDFDSLS(ph)VGR ddPTM_HeLa_Curcumin_4h_R1 1 TIDFDSLSVGR 11 0 A0A1C7CYX9 A0A1C7CYX9 1 0 TIDFDSLS(1)VGR 142.76 0.0011752 4516800 1545.7 1739.3 1938.2 2522.2 2036.6 3110.9 2364.5 1958.5 2018.4 2447.3 TRUE FALSE FALSE 1423.356214 1889.637342 2010.031397 2511.763805 2012.314875 2465.664273 2430.841506 2555.637634 1796.98657 2532.343493 0.562070753 0.746201038 0.793743583 0.991873264 0.794645308 0.973668967 0.959917765 1.00919865 0.709614069 1 11.30625739 -6.295319646 10.92730062 0.783684271 0.939772084 0.38057966 0.115346663 1.247966294 400.2831503 0.026367823 0.040389695 5.07E-07 6.295319646 0.156087812 TIDGSK(ac)TCTIEDVSR ddPTM_HeLa_Curcumin_4h_R1 1 TIDGSKTCTIEDVSR 15 1 Q96PU4;B1AL33;Q96PU4-2 Q96PU4 UHRF2 E3 ubiquitin-protein ligase UHRF2 0 1 TIDGSK(1)TCTIEDVSR 177.21 3.06E-07 1458500 428.13 493.78 261.72 319.07 333.25 752.38 249.4 184 415.96 325.43 FALSE TRUE FALSE 394.2430587 536.460143 271.4195734 317.7497729 329.2762114 596.3279069 256.3974928 240.100753 370.3302287 336.7386683 1.170768599 1.593105258 0.806024371 0.9436094 0.977839026 1.770892277 0.761413871 0.713018063 1.099755578 1 8.395485588 TIDLGAAAHYTGDKAS(ph)PDQNASTHTPQSSVK ddPTM_HeLa_Curcumin_4h_R1 1 TIDLGAAAHYTGDKASPDQNASTHTPQSSVK 31 1 Q14677-2;Q14677;Q14677-3 Q14677-2 CLINT1 Clathrin interactor 1 1 0 TIDLGAAAHY(0.008)T(0.026)GDKAS(0.811)PDQNAS(0.096)T(0.052)HT(0.006)PQS(0.001)SVK 58.342 0.00065194 43119000 419.37 442.74 295.41 260.26 590.58 1585.1 503.01 547.71 868.49 476.78 TRUE FALSE FALSE 386.176422 481.0084728 306.3581545 259.1831131 583.5377192 1256.332392 517.1231068 714.7042577 773.2188199 493.3480695 0.782766663 0.974988051 0.62097771 0.525355482 1.182811397 2.546543647 1.048191204 1.448681574 1.56728863 1 8.946462053 -5.516371214 24.94738649 0.855157896 1.658982976 0.377647597 0.437764363 172.6822745 661996.6579 0.051706276 0.106520193 3.05E-06 5.516371214 0.80382508 TIEGSS(ph)PADNRYSEYAEEFSK ddPTM_HeLa_Curcumin_4h_R1 1 TIEGSSPADNRYSEYAEEFSK 21 1 Q9Y217 Q9Y217 MTMR6 Myotubularin-related protein 6 1 0 T(0.001)IEGS(0.166)S(0.826)PADNRY(0.003)S(0.004)EYAEEFSK 73.574 0.001048 7403800 1663.1 1255.7 1342 1381.2 1371.4 1358.1 1028.9 657.36 1527.6 1277.2 TRUE FALSE FALSE 1531.46388 1364.237113 1391.735701 1375.48496 1355.046951 1076.414751 1057.768165 857.7860379 1360.026102 1321.582605 1.158810561 1.032275325 1.053082641 1.040786217 1.025321418 0.814489194 0.800379909 0.649059722 1.029088985 1 10.36805089 -4.956221767 1.044274003 1.07312299 0.64048191 0.887840983 0.048982143 0.220313853 0.351554884 0.00999804 0.080444499 1.11E-05 4.956221767 -0.43264108 TIET(ph)SPSLSR ddPTM_HeLa_Curcumin_4h_R1 1 TIETSPSLSR 10 0 H3BP78;F8W7R3;Q9NVI1-2;Q9NVI1-1;Q9NVI1 H3BP78 FANCI Fanconi anemia group I protein 1 0 T(0.001)IET(0.496)S(0.496)PS(0.007)LSR 146.11 0.0031386 127570000 2912.1 2684.7 2603.1 3066.4 2788.4 3603.3 2248.5 1424.1 3721.7 2736.4 TRUE FALSE FALSE 2681.604212 2916.753505 2699.573176 3053.712049 2755.150151 2855.934962 2311.586858 1858.301534 3313.438821 2831.489696 0.947064796 1.030112703 0.953410913 1.078482487 0.973039088 1.008633359 0.816385404 0.65629818 1.170210446 1 11.46734556 -4.506261899 2.564857116 0.986195149 0.652075678 0.72762389 0.070065491 0.079635567 0.898132767 0.005665472 0.044988429 3.12E-05 4.506261899 -0.33411947 TIFAYFTGSK ddPTM_HeLa_Curcumin_4h_R1 2 TIFAYFTGSK 10 0 I3L0K2;I3L3M7;Q9BRA2 I3L0K2 TXNDC17 Thioredoxin domain-containing protein 17 0 0 ; ; 140.16 3.45E-05 618030 342.61 159.18 270.78 307.73 217.29 425.49 372.45 404.17 314.53 177.25 FALSE FALSE TRUE 315.492057 172.9388099 280.815345 306.4566948 214.6989587 337.2385777 382.8999446 527.3995724 280.0268459 183.4094243 1.720151831 0.942911252 1.5310846 1.670888483 1.170599382 1.838720006 2.087678679 2.875531475 1.52678548 1 7.518923962 -1 0.560479644 1.315563776 78.14678586 0.765889575 0.261200139 50.96450905 0.412472297 0.056610581 4751.922387 0.1 1 76.83122208 up TIGGGDDS(ph)FNTFFSETGAGK ddPTM_HeLa_Curcumin_4h_R1 3 TIGGGDDSFNTFFSETGAGK 20 0 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;A0A1W2PQM2;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;F8W0F6;F8VXZ7;P68363;P68363-2 Q9BQE3;P68363 TUBA1C;TUBA1B;TUBA1A;TUBA3E Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain 1 0 TIGGGDDS(0.905)FNT(0.095)FFSETGAGK;TIGGGDDS(1)FNTFFSETGAGK;TIGGGDDS(0.985)FNT(0.015)FFSETGAGK ;; 194.92 1.82E-10 296026000 14982 13429.1 15209.3 15640.5 15111.5 19954.6 13225.6 16046.2 16625.4 15165.7 TRUE FALSE FALSE 13796.15889 14589.85157 15772.97004 15575.78376 14931.30523 15815.79103 13596.67474 20938.61251 14801.63521 15692.70695 0.87914462 0.929721788 1.005114675 0.992549202 0.951480537 1.007843394 0.866432719 1.334289399 0.943217462 1 13.93780661 -4.253799878 24.94167429 0.949512328 1.334289589 0.849494015 0.048150103 291.193968 950675.4967 0.007808102 0.111225495 5.57E-05 4.253799878 0.384777262 TIGGGDDSFNT(ph)FFSETGAGK ddPTM_HeLa_Curcumin_4h_R1 1 TIGGGDDSFNTFFSETGAGK 20 0 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;A0A1W2PQM2;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;F8W0F6;F8VXZ7;P68363;P68363-2 Q9BQE3;P68363 TUBA1C;TUBA1B;TUBA1A;TUBA3E Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain 1 0 TIGGGDDS(0.496)FNT(0.503)FFSETGAGK 161.2 2.46E-05 240910000 9275.1 8784.6 9302.5 8284.2 9017.8 12240 8250.7 9690.7 10496 8629.8 TRUE FALSE FALSE 8540.966048 9543.901681 9647.258833 8249.922175 8910.268625 9701.286027 8482.192436 12645.34982 9344.61506 8929.684908 0.956468916 1.068783701 1.080358258 0.923876067 0.997825647 1.086408549 0.949887093 1.416102578 1.046466382 1 13.12439355 -4.25770973 24.9951487 0.994918509 1.416102739 0.816568303 0.05689564 103.296865 692239.4903 0.007577641 0.075594584 5.52E-05 4.25770973 0.42118423 TIGGGDDSFNTFFS(ph)ETGAGK ddPTM_HeLa_Curcumin_4h_R1 1 TIGGGDDSFNTFFSETGAGK 20 0 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;A0A1W2PQM2;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;F8W0F6;F8VXZ7;P68363;P68363-2 Q9BQE3;P68363 TUBA1C;TUBA1B;TUBA1A;TUBA3E Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain 1 0 TIGGGDDSFNTFFS(0.5)ET(0.5)GAGK 185.87 1.33E-29 0 1443.4 1496 1246.3 1447.7 1440.1 1902.9 1128.1 1243.5 1394.5 887.22 TRUE FALSE FALSE 1329.153367 1625.307574 1292.488974 1441.709801 1422.927748 1508.21709 1159.75145 1622.637426 1241.526839 918.050829 1.447799321 1.770389528 1.407862107 1.570403027 1.549944407 1.642847043 1.263275859 1.767481031 1.352350872 1 9.842430222 -8.730217771 0.655542542 0.992199624 1.557581817 0.356664338 0.180492259 0.323465564 0.266726288 0.093922193 0.032679694 1.86E-09 8.730217771 0.565382193 TIGGGDDSFNTFFSET(ph)GAGK ddPTM_HeLa_Curcumin_4h_R1 1 TIGGGDDSFNTFFSETGAGK 20 0 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;A0A1W2PQM2;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;F8W0F6;F8VXZ7;P68363;P68363-2 Q9BQE3;P68363 TUBA1C;TUBA1B;TUBA1A;TUBA3E Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain 1 0 TIGGGDDSFNTFFS(0.143)ET(0.857)GAGK 191.97 2.52E-29 0 1542 1216.7 1454.2 1395.4 1492.8 1623 1187 1056.8 1365.4 1053.4 TRUE FALSE FALSE 1419.949073 1321.866126 1508.093931 1389.626205 1474.999335 1286.371505 1220.304025 1379.013455 1215.619036 1090.005572 1.302698913 1.212715018 1.383565342 1.27487991 1.353203482 1.180151312 1.119539255 1.265143492 1.115241121 1 10.09011979 -9.27529624 0.88998323 0.991866705 1.262321371 0.482882068 0.081195132 0.334921905 0.453230464 0.06133878 0.014784696 5.31E-10 9.27529624 0.270454666 TIGGGDDSFNTFFSETGAGK ddPTM_HeLa_Curcumin_4h_R1 2 TIGGGDDSFNTFFSETGAGK 20 0 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;A0A1W2PQM2;P0DPH7-2;F8VVB9;F8VQQ4;Q6PEY2;F8VRZ4;F8VS66;F8VWV9;F8VX09;F8VRK0;F8W0F6;F8VXZ7;P68363;P68363-2 Q9BQE3;P68363 TUBA1C;TUBA1B;TUBA1A;TUBA3E Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-1B chain 0 0 ; ; 228.73 2.36E-24 90769000 2675.7 2167.25 2620.1 2356.7 2656.7 3726.2 2823.7 3547 2753.8 2590.9 FALSE FALSE TRUE 2463.915522 2354.577433 2717.203211 2346.9486 2625.020588 2953.344117 2902.925422 4628.463972 2451.71503 2680.933582 0.91905131 0.878267723 1.013528731 0.875422135 0.979144207 1.101610326 1.082803931 1.726437388 0.914500473 1 11.38851976 TIGGGDDSFTTFFCETGAGK ddPTM_HeLa_Curcumin_4h_R1 2 TIGGGDDSFTTFFCETGAGK 20 0 P68366-2;P68366;C9JEV8;C9JQ00;C9JJQ8;C9JDL2 P68366-2 TUBA4A Tubulin alpha-4A chain 0 0 ; ; 202.13 1.01E-12 20225300 3131.5 2725.97 2845.2 2699.69 2773.63 4067.3 2988.9 2525.38 3783.9 3123 FALSE FALSE TRUE 2883.638471 2961.5907 2950.645615 2688.519398 2740.556274 3223.696132 3072.76049 3295.356737 3368.815637 3231.524018 0.892346291 0.916468726 0.913081753 0.831966398 0.848069288 0.997577649 0.950870386 1.019753132 1.042485099 1 11.657999 TIIFVETK ddPTM_HeLa_Curcumin_4h_R1 1 TIIFVETK 8 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 0 111.04 0.0059256 1001400 1504.6 1053.4 1093.2 1602.5 1280.6 1525.9 1424.4 1259 1093.3 1264.5 FALSE FALSE TRUE 1385.509322 1144.451202 1133.714954 1595.86928 1265.329681 1209.41114 1464.36483 1642.863304 973.3677253 1308.441281 1.05890065 0.874667606 0.866462233 1.219672065 0.967051178 0.924314417 1.119167403 1.255588102 0.743913953 1 10.35363347 -4.47231506 3.71304853 1.009714957 1.244265193 0.299474217 0.128877001 0.185599106 4.890219551 0.013366318 0.085431048 3.37E-05 4.47231506 0.234550236 TIIPLISQCTPK ddPTM_HeLa_Curcumin_4h_R1 2 TIIPLISQCTPK 12 0 P40926;P40926-2;G3XAL0 P40926 MDH2 "Malate dehydrogenase, mitochondrial;Malate dehydrogenase" 0 0 ; ; 202.16 2.81E-20 3008000 2414.93 2529.41 2823.24 2996.05 2894.48 4158.7 2729.73 3050.21 3259.69 2170.27 FALSE FALSE TRUE 2223.785742 2748.04093 2927.871758 2983.653139 2859.965216 3296.138742 2806.318877 3980.204988 2902.110162 2245.686721 0.990247536 1.223697368 1.303775692 1.328615034 1.273537039 1.467764275 1.249648426 1.772377665 1.292304102 1 11.13294097 -4.607277035 0.269754961 0.940450651 2.01549299 0.452160261 0.156351401 2.727780626 0.178290624 0.07386877 0.957087128 2.47E-05 4.607277035 1.075042339 TIIQNPTDQQK ddPTM_HeLa_Curcumin_4h_R1 1 TIIQNPTDQQK 11 0 Q9UQ80;Q9UQ80-2;F8VR77 Q9UQ80 PA2G4 Proliferation-associated protein 2G4 0 0 173.64 3.62E-09 1654500 1126.4 745.88 802.72 1098 1034.6 1114.3 967.59 797.96 859.75 942.98 FALSE FALSE TRUE 1037.244251 810.3505436 832.4695093 1093.456767 1022.263071 883.1816193 994.7379713 1041.254331 765.437576 975.7484848 1.063024199 0.830491214 0.85315993 1.120633835 1.047670672 0.905132453 1.019461456 1.067133946 0.784461967 1 9.930365507 TILETS(ph)FHQHR ddPTM_HeLa_Curcumin_4h_R1 2 TILETSFHQHR 11 0 Q5M775-4;Q5M775;Q5M775-5;Q5M775-3;Q5M775-2 Q5M775-4 SPECC1 Cytospin-B 1 0 TILET(0.182)S(0.818)FHQHR;TILET(0.242)S(0.758)FHQHR ; 195.77 9.15E-06 19071000 4005.1 3392.28 3410.5 3598.8 3519 4965.8 3612.4 1229.35 4156.6 3741.5 TRUE FALSE FALSE 3688.092109 3685.493567 3536.89613 3583.909119 3477.038223 3935.837104 3713.754222 1604.173156 3700.631379 3871.516847 0.952621997 0.951950802 0.913568575 0.925711875 0.898107476 1.01661371 0.959250436 0.414352622 0.955860849 1 11.9186832 -4.261563365 8.004078872 0.964296501 0.40992148 0.952951974 0.035798332 0.014752562 11.55289314 0.005567305 0.044061282 5.48E-05 4.261563365 -0.554375021 TIMQVSS(ph)GSRGSSGEAT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 TIMQVSSGSRGSSGEATR 18 1 K7EJ87 K7EJ87 POLR2E 2 0 T(0.264)IMQVS(0.333)S(0.395)GS(0.008)RGS(0.001)S(0.095)GEAT(0.904)R 74.561 0.016108 67635000 0 0 0 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 0 0 0 0 0 0 TINEVENQILTR ddPTM_HeLa_Curcumin_4h_R1 2 TINEVENQILTR 12 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144;P12814-4;P12814-3;P12814;P12814-2;H9KV75;H7C5W8;H0YJW3;H0YJ11 O43707;P12814-4 ACTN4;ACTN1 Alpha-actinin-4;Alpha-actinin-1 0 0 ; ; 136.01 0.00026262 10552000 1621.24 1182.53 1532.44 1426.37 1416.36 1858.03 1520.29 1482.8 1138.58 1205.55 FALSE FALSE TRUE 1492.917143 1284.742624 1589.233574 1420.468059 1399.470832 1472.653634 1562.945246 1934.898894 1013.680623 1247.442773 1.19678207 1.029901052 1.273993172 1.138703987 1.12187177 1.18053803 1.252919396 1.551092312 0.812606914 1 10.28475792 -1 0.691487195 1.102492802 53.24409954 0.59474108 0.117607062 109.8785207 0.562511079 0.014933327 8858.246479 0.1 1 52.14160673 TINNQHSVESQDNDQPDY(ph)DS(ph)VASDEDTDLETTASK ddPTM_HeLa_Curcumin_4h_R1 1 TINNQHSVESQDNDQPDYDSVASDEDTDLETTASK 35 0 F8VXI9;Q14161-6;Q14161-4;Q14161-3;Q14161;R4GNG3;F8WAK2;Q14161-11;Q14161-7;Q14161-10;Q14161-8;Q14161-5;F8W822;Q14161-2 F8VXI9 GIT2 ARF GTPase-activating protein GIT2 2 0 TINNQHSVES(0.001)QDNDQPDY(0.444)DS(0.468)VAS(0.306)DEDT(0.306)DLET(0.232)T(0.2)AS(0.043)K 63.967 8.82E-05 3027700 1157.2 746.59 924.36 753.87 913.8 1020.2 800.07 401.04 950.94 950.02 TRUE FALSE FALSE 1065.606399 811.1219129 958.6175947 750.7506857 902.9035318 808.59902 822.5178109 523.3152498 846.6242611 983.0331243 1.083998466 0.825121649 0.975163065 0.763708432 0.918487393 0.822555212 0.836714237 0.532347524 0.861236758 1 9.94109622 -3.366820364 0.31535169 1.043642792 4.38E-15 0.459666476 0.10555717 5.378714708 0.249365852 0.035331408 2.403860433 0.000429714 3.366820364 -1.043642792 TIPWLEDR ddPTM_HeLa_Curcumin_4h_R1 1 TIPWLEDR 8 0 O43707;O43707-2;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 0 112.17 0.005296 1090300 947.08 2494.2 1641.8 929.14 1476.5 2145.2 2463.3 1988.9 1031.7 975.49 FALSE FALSE TRUE 872.1176186 2709.787534 1702.646552 925.2954649 1458.893702 1700.261339 2532.413568 2595.306454 918.5250912 1009.388205 0.864006152 2.684584108 1.68681043 0.916689397 1.445324697 1.684447401 2.508859878 2.571167804 0.909981994 1 9.979265418 -1 0.231976173 0.877752392 10.98841593 0.420327348 0.528664144 31.77532819 0.387643851 0.369387336 123.6219172 0.1 1 10.11066354 TIPWLEDRVPQK ddPTM_HeLa_Curcumin_4h_R1 1 TIPWLEDRVPQK 12 1 O43707;O43707-2;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 0 110.93 0.0014745 1238700 839.09 565.59 875.77 418.23 615.37 859.24 661.22 700.15 563.57 563.62 FALSE FALSE TRUE 772.6751411 614.4770794 908.2268066 416.4994751 608.0321147 681.0239384 679.7720536 913.6225119 501.747781 583.205753 1.324875718 1.053619715 1.557300836 0.714155292 1.042568787 1.167725001 1.165578443 1.56655264 0.860327214 1 9.187861141 -9.598660848 1.404837911 1.000353075 1.202399667 0.149490076 0.241815623 0.853197421 3.029583654 0.160891465 0.037499678 2.52E-10 9.598660848 0.202046592 TIQAPTQVPVVVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 TIQAPTQVPVVVSPR 15 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 0 TIQAPTQVPVVVS(1)PR 129.29 0.00073575 5717400 1754.6 1345.1 1375.6 1404 1429.8 2259.6 1664.8 1277.8 1553.5 1438.6 TRUE FALSE FALSE 1615.721559 1461.36445 1426.580946 1398.19062 1412.750569 1790.933489 1711.509807 1667.395338 1383.084937 1488.591243 1.085403106 0.981709692 0.958342965 0.939271023 0.949052049 1.203106291 1.149751361 1.120116315 0.929123386 1 10.53973194 -5.255902366 24.99969859 1.017340515 1.156867329 0.642300084 0.05635887 279.0363865 1259848.849 0.008761513 0.021655538 5.55E-06 5.255902366 0.139526815 TIQEMQQK ddPTM_HeLa_Curcumin_4h_R1 1 TIQEMQQK 8 0 O43707;O43707-2;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 0 128.38 0.001156 0 1161.4 991.63 916.86 1098.7 948.25 1071.2 842.76 785.04 1108.5 905.44 FALSE FALSE TRUE 1069.473964 1077.342079 950.8396382 1094.153871 936.9427381 849.0210451 866.4055774 1024.395082 986.9003233 936.9039726 1.14149795 1.149895945 1.014874166 1.167839931 1.000041376 0.906198575 0.924753873 1.09338322 1.053363367 1 9.871757377 -5.537951173 24.56690472 1.077548905 0.967000059 0.353450004 0.070325816 177.6796173 289603.4811 0.011377307 0.022761524 2.90E-06 5.537951173 -0.110548846 TIQEVLEEQS(ph)EDEDR ddPTM_HeLa_Curcumin_4h_R1 2 TIQEVLEEQSEDEDR 15 0 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 TIQEVLEEQS(1)EDEDR;TIQEVLEEQS(1)EDEDR ; 252.25 6.48E-39 20141500 2486 2289.38 2739.65 2499.86 2898.97 2870.22 2624 2082.35 2379.26 2301.2 TRUE FALSE FALSE 2289.230477 2487.263806 2841.183839 2489.516242 2864.401676 2274.904018 2697.622378 2717.248929 2118.261131 2381.166529 0.961390331 1.044556849 1.193189894 1.045502787 1.202940509 0.955373759 1.132899503 1.141141914 0.889589663 1 11.2174528 -7.000003645 8.768469893 0.982829478 1.107867973 0.473119169 0.073923303 0.071236651 68.87191652 0.010234012 0.01315374 1.00E-07 7.000003645 0.125038495 TIQEVLEEQS(ph)EDEDREAK ddPTM_HeLa_Curcumin_4h_R1 4 TIQEVLEEQSEDEDREAK 18 1 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK;TIQEVLEEQS(1)EDEDREAK ;;; 160.2 1.51E-05 1009223000 10065.2 8563.1 9071.1 10003.8 9798.4 10446.2 9522 8131.5 9381.6 8535.9 TRUE FALSE FALSE 9268.528799 9303.256208 9407.282946 9962.406926 9681.56048 8279.540367 9789.161693 10610.75692 8352.461952 8832.52189 1.049363807 1.053295573 1.065073267 1.127923265 1.096126407 0.937392567 1.108308795 1.20132812 0.945648599 1 13.1086097 -1 0.099524982 0.959476569 1.421891299 0.356966673 0.062163336 130.4743193 0.926711891 0.505889298 8.276731037 0.1 1 0.462414731 TIQEVLEEQS(ph)EDEDREAKR ddPTM_HeLa_Curcumin_4h_R1 2 TIQEVLEEQSEDEDREAKR 19 2 M0R0Q7;P18858-2;P18858;P18858-3 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 T(0.001)IQEVLEEQS(0.999)EDEDREAKR;TIQEVLEEQS(1)EDEDREAKR ; 55.247 0.0088333 152118000 9179.3 7432.7 7309.6 8656.1 7992.4 9308.9 7892.3 7721.9 9559 8324.2 TRUE FALSE FALSE 8452.748719 8075.149469 7580.500206 8620.283352 7897.09585 7378.129207 8113.736697 10076.27176 8510.401615 8613.46533 0.981341237 0.937502986 0.880075546 1.000791554 0.916831443 0.856580821 0.941982859 1.169827866 0.988034582 1 13.07237806 -7.448291446 3.764662358 0.992233646 0.950399373 0.02750616 0.08118744 0.587227163 15.26886908 0.014014714 0.015653468 3.56E-08 7.448291446 -0.041834273 TIQFVDWCPTGFK ddPTM_HeLa_Curcumin_4h_R1 1 TIQFVDWCPTGFK 13 0 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;A0A1W2PQM2;P0DPH7-2;Q6PEY2;Q9NY65-2;Q9NY65;C9J2C0;V9GZ17 Q9BQE3 TUBA1C;TUBA3E;TUBA8 Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain 0 0 183.66 7.28E-09 452690 1198.8 1103.6 1389.1 1379.9 1094.4 810.32 740.31 445.21 135.79 0 FALSE FALSE TRUE 1103.913715 1198.990266 1440.581268 1374.190339 1081.349995 642.2504978 761.0811062 580.9524795 120.8941767 0 0 TIQGDEEDLR ddPTM_HeLa_Curcumin_4h_R1 1 TIQGDEEDLR 10 0 M0R213;M0R0Y2;P54920 M0R213 NAPA Alpha-soluble NSF attachment protein 0 0 112.13 0.004718 1397600 1387.5 901.79 1222.1 1074.1 1277.8 1776.8 1070.8 1213.9 1716.2 934.3 FALSE FALSE TRUE 1277.677911 979.7367093 1267.392101 1069.655659 1262.56307 1408.271651 1100.843766 1584.012522 1527.937154 966.7668555 1.321598795 1.0134157 1.310959404 1.106425663 1.305964372 1.456681767 1.138685878 1.638463827 1.580460837 1 9.917024203 -1.2328489 0.030633263 2.70E-19 3.084097206 0 0.224002565 897.3959379 2.211621738 71.99475716 170.4402589 0.058499358 1.2328489 3.084097206 TIQNSSVS(ph)PTSSSSSSSSTGETQTQSSSR ddPTM_HeLa_Curcumin_4h_R1 1 TIQNSSVSPTSSSSSSSSTGETQTQSSSR 29 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 TIQNS(0.005)S(0.015)VS(0.658)PT(0.281)S(0.038)S(0.002)SSSSSSTGETQTQSSSR 165.61 3.68E-16 10212000 2096.7 1846.3 1685.7 1794.2 2027.6 2707.6 1941.3 996.18 2177.4 1598.1 TRUE FALSE FALSE 1930.743983 2005.885945 1748.173525 1786.776076 2003.422194 2146.013239 1995.767653 1299.910696 1938.544668 1653.633856 1.167576471 1.213016979 1.057170859 1.080514933 1.211527078 1.297755988 1.206898157 0.786093422 1.17229377 1 10.69142412 -9.304453288 0.994613111 0.998775528 1.139032478 0 0.142703619 0.910758948 1.592577685 0.09134246 0.023591839 4.96E-10 9.304453288 0.14025695 TIQNSSVSPT(ph)SSSSSSSSTGETQTQSSSR ddPTM_HeLa_Curcumin_4h_R1 1 TIQNSSVSPTSSSSSSSSTGETQTQSSSR 29 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 TIQNSS(0.001)VS(0.053)PT(0.407)S(0.407)S(0.123)S(0.005)S(0.002)S(0.001)SSSTGETQTQSSSR 123.62 2.49E-12 10864000 1784.2 1728.6 1592 1963.9 1590.7 2343.8 2106.2 1013.5 1983.6 1651 TRUE FALSE FALSE 1642.978687 1878.012482 1651.00092 1955.773902 1571.731941 1857.66946 2165.294303 1322.511484 1766.004043 1708.372127 0.961721783 1.099299416 0.966417617 1.144817263 0.920017317 1.087391576 1.267460566 0.774135485 1.033734989 1 10.73840655 -7.283221626 24.4043735 0.981924174 1.044797008 0.011463998 0.12757669 1375.919545 1541546.705 0.019564548 0.022386558 5.21E-08 7.283221626 0.062872834 TIS(ph)DGTISASK ddPTM_HeLa_Curcumin_4h_R1 1 TISDGTISASK 11 0 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 0 T(0.348)IS(0.631)DGT(0.022)ISASK 163.45 0.00028788 85816000 6327.2 5457.8 6149.3 6201.1 6187.2 7466.6 6357.1 4295.5 6537.4 5668.3 TRUE FALSE FALSE 5826.395444 5929.547913 6377.198467 6175.441491 6113.421681 5917.942994 6535.463117 5605.178176 5820.263576 5865.273003 0.993371569 1.010958554 1.087280756 1.052882191 1.042308121 1.008979973 1.114264095 0.95565512 0.992326116 1 12.51798255 -6.983403552 24.26544667 0.997148597 1.045866033 0.233477536 0.039999503 162.4792188 237557.2644 0.00572543 0.007523478 1.04E-07 6.983403552 0.048717436 TIS(ph)DGTISASKQESGK ddPTM_HeLa_Curcumin_4h_R1 1 TISDGTISASKQESGK 16 1 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 0 T(0.226)IS(0.711)DGT(0.063)ISASKQESGK 103.66 0.020133 7624800 1811.9 1317.1 1129.8 1566.1 829.34 2010.3 1066 913.07 2697.4 1811.4 TRUE FALSE FALSE 1668.486203 1430.944255 1171.671382 1559.619893 819.4506622 1593.341119 1095.909091 1191.46084 2401.501969 1874.346015 0.890169792 0.76343655 0.625109437 0.832087502 0.437192842 0.850078431 0.584688783 0.635667497 1.281247939 1 10.87217159 -7.281316288 0.841082363 0.97473092 0.647907664 0.573074806 0.14887919 0.246697021 0.354170354 0.024748031 0.029118223 5.23E-08 7.281316288 -0.326823255 TIS(ph)PSTSNNIPLMR ddPTM_HeLa_Curcumin_4h_R1 1 TISPSTSNNIPLMR 14 0 O94806;O94806-2;F8WBA3;Q15139 O94806 PRKD3;PRKD1 Serine/threonine-protein kinase D3;Serine/threonine-protein kinase;Serine/threonine-protein kinase D1 1 0 T(0.203)IS(0.732)PS(0.038)T(0.01)S(0.018)NNIPLMR 108.71 0.0045147 0 514.63 306.89 347.74 367.02 595.96 388.11 404.26 438.58 503.1 318.24 TRUE FALSE FALSE 473.8964925 333.4162041 360.6275503 365.5013685 588.8535662 307.6116111 415.6024476 572.301023 447.9111887 329.2988163 1.439107792 1.0125035 1.095137706 1.1099383 1.788204321 0.93414126 1.262083029 1.737938294 1.360196777 1 8.363253516 -9.532971159 1.231506104 0.996440078 1.297167928 0 0.294267522 0.760727775 2.02584816 0.19684128 0.044692691 2.93E-10 9.532971159 0.30072785 TISDGT(ph)ISASKQESGK ddPTM_HeLa_Curcumin_4h_R1 2 TISDGTISASKQESGK 16 1 A0A075B6Q2;S4R347;Q5T0N5-3;Q5T0N5-4;Q5T0N5-2;Q5T0N5-5;Q5T0N5 A0A075B6Q2 FNBP1L Formin-binding protein 1-like 1 0 T(0.13)IS(0.13)DGT(0.74)ISASKQESGK;T(0.32)IS(0.108)DGT(0.404)IS(0.164)AS(0.003)KQESGK ; 82.578 0.0088874 38986000 8164.9 6092.7 6213.9 6857.7 4382.8 9314.4 5816.9 4145 11473.9 9010.4 TRUE FALSE FALSE 7518.639549 6619.325839 6444.1926 6829.324654 4330.537973 7382.488445 5980.106559 5408.791419 10215.24188 9323.510729 0.806417214 0.709960661 0.691176617 0.732484238 0.464475035 0.791814227 0.641400727 0.580123901 1.09564328 1 13.18665758 -7.911311259 0.418857108 1.016151227 0.616467564 0.751381373 0.088415406 0.366777762 0.16553762 0.058286511 0.036932714 1.23E-08 7.911311259 -0.399683663 TISHVIIGLK ddPTM_HeLa_Curcumin_4h_R1 1 TISHVIIGLK 10 0 Q9Y265;Q9Y265-2;E7ETR0 Q9Y265 RUVBL1 RuvB-like 1 0 0 118.18 1.41E-07 0 9177.1 7052.4 6606.2 6118.2 7012.6 17343 10941 10459 8716.2 8375.7 FALSE FALSE TRUE 8450.722851 7661.978031 6851.031583 6092.88451 6928.979325 13745.8663 11247.97501 13647.90095 7760.054667 8666.754952 0.975073473 0.884065382 0.790495592 0.703017974 0.79948947 1.58604534 1.29783005 1.574741761 0.895381802 1 13.0812762 -5.260546422 25 0.931925126 1.467368168 0.834698698 0.12426526 28.82975131 807123.9225 0.01988633 0.047646036 5.49E-06 5.260546422 0.535443042 TISIDENMEPS(ph)PTGDFYPSPS(ph)SPAAGSR ddPTM_HeLa_Curcumin_4h_R1 2 TISIDENMEPSPTGDFYPSPSSPAAGSR 28 0 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 2 0 TISIDENMEPS(0.726)PT(0.263)GDFY(0.012)PS(0.009)PS(0.574)S(0.402)PAAGS(0.014)R;TISIDENMEPS(0.544)PT(0.202)GDFY(0.239)PS(0.019)PS(0.509)S(0.465)PAAGS(0.022)R ; 92.731 2.54E-07 24131400 2820.1 2837.31 2772.84 3200.5 3072.5 3026.5 2396 1544.95 3456.8 2978.5 TRUE FALSE FALSE 2596.886109 3082.554434 2875.60389 3187.257179 3035.862444 2398.769784 2463.225311 2015.998143 3077.597688 3082.002653 0.842596974 1.000179033 0.933030958 1.034151342 0.985029147 0.778315289 0.79922881 0.654119535 0.998570746 1 11.58965239 -5.128054337 3.74454226 0.942017373 0.737246246 0.71259096 0.064493353 0.13059363 3.238575846 0.010931629 0.030481951 7.45E-06 5.128054337 -0.204771127 TISIDENMEPS(ph)PTGDFYPSPSS(ph)PAAGSR ddPTM_HeLa_Curcumin_4h_R1 1 TISIDENMEPSPTGDFYPSPSSPAAGSR 28 0 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 2 0 TISIDENMEPS(0.959)PT(0.024)GDFY(0.017)PS(0.019)PS(0.288)S(0.688)PAAGS(0.005)R 93.805 2.27E-07 8339500 1394.5 1263.3 1038.6 1493.8 1434 1549.7 1151.8 826.01 1665.3 1243.5 TRUE FALSE FALSE 1284.123854 1372.494023 1077.09143 1487.619051 1416.900487 1228.274751 1184.116408 1077.856647 1482.620756 1286.711532 0.997988921 1.066668005 0.837088502 1.156140296 1.101179597 0.954584396 0.920265637 0.83768321 1.152255746 1 10.32947294 -4.632562658 2.137049683 1.009566631 0.844232794 0.3091229 0.092369772 0.326201865 2.604729809 0.010926213 0.076889427 2.33E-05 4.632562658 -0.165333838 TISIDENMEPSPTGDFYPSPS(ph)SPAAGSR ddPTM_HeLa_Curcumin_4h_R1 3 TISIDENMEPSPTGDFYPSPSSPAAGSR 28 0 Q5VW31;A0A1B0GWB8;A0A2R8Y7V8;Q5VW30;Q5VW27;A0A1B0GWI9;A0A1B0GU97;A0A0A0MRX8;A0A1B0GWJ4;A0A1B0GVN4;U3KQE8;A0A1B0GW37;Q5VW26;O00712-4;O00712;O00712-5;O00712-6 Q5VW31 NFIB Nuclear factor 1;Nuclear factor 1 B-type 1 0 TISIDENMEPSPTGDFYPS(0.088)PS(0.453)S(0.453)PAAGS(0.006)R;TISIDENMEPS(0.055)PT(0.019)GDFY(0.048)PS(0.282)PS(0.435)S(0.155)PAAGS(0.005)R;TISIDENMEPSPTGDFYPSPS(0.499)S(0.499)PAAGS(0.001)R ;; 135.06 4.06E-10 42162500 9421.6 7404.1 8163.1 8402.5 8087.3 10096.9 7929.2 4869.3 9276.6 8454.6 TRUE FALSE FALSE 8675.870418 8044.077412 8465.631667 8367.732681 7990.864229 8002.689124 8151.672012 6353.927154 8258.980189 8748.396721 0.991709761 0.919491613 0.967678071 0.956487565 0.913408992 0.914760656 0.931790392 0.726296184 0.944056431 1 13.09480293 -2.767681109 0.463330375 0.991010607 2.67E-31 0.713193916 0.038997479 5.13684824 0.258513225 0.007491074 3.806842158 0.001707336 2.767681109 -0.991010607 GSES(ph)PNSFLDQESR ddPTM_HeLa_Curcumin_4h_R1 2 GSESPNSFLDQESR 14 0 Q5T4Y8;A0A5H1ZRR2;G9CGD6-3;G9CGD6;G9CGD6-2;Q6P9H4 Q5T4Y8 CNKSR3 Connector enhancer of kinase suppressor of ras 3 1 0 GS(0.132)ES(0.867)PNS(0.001)FLDQESR;GS(0.003)ES(0.997)PNSFLDQESR ; 240.5 1.37E-28 30854000 5078 4589 4741 4341.5 4497.6 5233.5 3515.4 1553.24 5469.9 4399.9 TRUE FALSE FALSE 4676.070942 4985.652712 4916.705631 4323.536023 4443.969057 4148.013106 3614.032663 2026.815726 4869.865655 4552.796198 1.02707671 1.095074872 1.079930974 0.949644095 0.976096637 0.911091322 0.793805061 0.445180421 1.069642796 1 12.15253716 -4.078594369 1.031454823 1.020335785 4.41E-17 0.94691745 0.042470169 0.387671853 0.251322724 0.006406121 0.47401917 8.34E-05 4.078594369 -1.020335785 down TISLVIR ddPTM_HeLa_Curcumin_4h_R1 1 TISLVIR 7 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 111.28 0.013057 3741600 2074.6 1460.9 2486.5 1855.4 2253.4 2421.4 2614.3 1984.3 1977.6 2331.3 FALSE FALSE TRUE 1910.393221 1587.173686 2578.651877 1847.722846 2226.529677 1919.174345 2687.650222 2589.303935 1760.662228 2412.312501 0.791934386 0.657946964 1.068954323 0.76595501 0.92298559 0.795574514 1.114138496 1.073370027 0.729864902 1 11.2362011 -4.750588705 24.98031886 0.880444822 1.09375438 0.369774553 0.123610135 187.0278095 430564.777 0.016896901 0.061972803 1.78E-05 4.750588705 0.213309558 TISPMVMDAK ddPTM_HeLa_Curcumin_4h_R1 1 TISPMVMDAK 10 0 P18206;P18206-2 P18206 VCL Vinculin 0 0 127.4 3.97E-08 0 512.52 358.66 456.91 418.45 670.1 667.26 482.08 467.42 338.06 470.69 FALSE FALSE TRUE 471.9535012 389.6609722 473.8434865 416.7185648 662.1094952 528.8627544 495.6058673 609.9342063 300.9756638 487.0464425 0.969011289 0.800048903 0.972891793 0.855603344 1.35943811 1.085856929 1.017574145 1.252312209 0.617960912 1 8.927915537 -5.779131439 24.99999885 0.960432839 1.160641172 0.437557875 0.151584446 160.5487733 226865.3617 0.015435604 0.028023358 1.66E-06 5.779131439 0.200208334 TITGNSAAVIT(ph)PFK ddPTM_HeLa_Curcumin_4h_R1 1 TITGNSAAVITPFK 14 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 0 TITGNS(0.008)AAVIT(0.992)PFK 176.29 0.00054002 16203000 2451.3 1853.5 2383.4 2771.8 2853.9 5424.8 4993.4 1002 2763.6 1819.1 TRUE FALSE FALSE 2257.277018 2013.708281 2471.730901 2760.331026 2819.869106 4299.63533 5133.501365 1307.505187 2460.439994 1882.31359 1.199203486 1.069804889 1.313134493 1.466456515 1.498086781 2.284229022 2.727229614 0.694626652 1.307136073 1 10.87829128 -5.873618362 1.463837835 1.10258247 1.953893324 0.259993576 0.497835023 0.310993536 1.337829291 0.072997447 0.168635798 1.34E-06 5.873618362 0.851310853 SGS(ph)YSYLEER ddPTM_HeLa_Curcumin_4h_R1 3 SGSYSYLEER 10 0 O14974-5;O14974-4;O14974-3;O14974-2;O14974;H0YIM2;H0YIS3;A0A0U1RQZ1 O14974-5 PPP1R12A Protein phosphatase 1 regulatory subunit 12A 1 0 S(0.067)GS(0.467)YS(0.467)YLEER;S(0.388)GS(0.606)YS(0.006)YLEER;S(0.271)GS(0.687)Y(0.002)S(0.04)YLEER ;; 203.03 1.06E-06 158251000 4214.11 4174.02 4519.92 4280.43 4525.48 5774.34 5313.78 6944.24 4076.59 3976.84 TRUE FALSE FALSE 3880.558747 4534.80369 4687.432211 4262.718715 4471.516607 4576.676794 5462.870365 9061.506809 3629.398276 4115.034894 0.943019645 1.102008563 1.139099019 1.035888838 1.086629086 1.112184201 1.327539257 2.202048595 0.881984812 1 12.00668895 -1.604446833 0.923420493 0.999851116 199.9998459 0.958379088 0.073145419 37.48475313 0.249925032 0.011463463 15506.86106 0.024862979 1.604446833 198.9999948 up TITVPVSGS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 TITVPVSGSPK 11 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 0 TITVPVS(0.138)GS(0.862)PK;TITVPVS(0.32)GS(0.68)PK ; 182.23 0.00012693 52955000 9192 6375 7406.7 7909.9 8526 11502.6 9755 4081.5 9639.2 7561.6 TRUE FALSE FALSE 8464.443501 6926.026594 7681.198818 7877.17093 8424.333019 9116.831099 10028.69905 5325.930561 8581.803876 7824.365037 1.081805803 0.885187048 0.981702513 1.006748905 1.076679447 1.165184786 1.281726888 0.680685338 1.096805151 1 12.93375796 -5.75314689 23.46967606 1.020006446 1.075695821 0.004693329 0.153762157 294.7967 834325.8883 0.020739834 0.040873622 1.77E-06 5.75314689 0.055689375 TIY(ph)TTAY(ph)KLPGILR ddPTM_HeLa_Curcumin_4h_R1 1 TIYTTAYKLPGILR 14 1 A0A096LNH6;Q14185 A0A096LNH6 DOCK1 Dedicator of cytokinesis protein 1 2 0 T(0.179)IY(0.698)T(0.301)T(0.058)AY(0.763)KLPGILR 45.28 0.018256 11325000 1697.7 2199.1 2121.5 1945.8 1709.4 2373.2 1550.4 1632.9 2487.4 1798.5 TRUE FALSE FALSE 1563.325254 2389.180405 2200.124656 1937.748795 1689.016521 1880.971569 1593.900051 2130.763693 2214.538443 1860.997741 0.84004683 1.283816929 1.182228547 1.041241885 0.907586551 1.01073286 0.856476081 1.1449577 1.189973741 1 10.86186059 TIYLS(ph)SPDSAVGVQWPR ddPTM_HeLa_Curcumin_4h_R1 1 TIYLSSPDSAVGVQWPR 17 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 0 TIYLS(0.614)S(0.383)PDS(0.002)AVGVQWPR 164.7 6.31E-13 0 893.28 834.31 758.67 747.61 972.8 1126.9 826.08 667.65 1091.1 1080.3 TRUE FALSE FALSE 822.5759454 906.4240388 786.7869776 744.5165879 961.1999954 893.1682372 849.2575815 871.2134115 971.4090598 1117.840345 0.735861744 0.81087075 0.703845573 0.666031237 0.859872342 0.799012347 0.759730659 0.779371952 0.869005189 1 10.12649843 -9.257080013 0.809662137 1.012682698 0.762532764 0.481833793 0.065101674 0.291267654 0.315524492 0.047062298 0.010606345 5.53E-10 9.257080013 -0.250149933 TKDGVVEITGK ddPTM_HeLa_Curcumin_4h_R1 2 TKDGVVEITGK 11 1 P04792 P04792 HSPB1 Heat shock protein beta-1 0 0 ; ; 108.72 0.0024019 45497000 22262 18411 22062 19745 22208 27348 21343 17445.6 21222 17955.3 FALSE FALSE TRUE 20499.93921 20002.3648 22879.63713 19663.30042 21943.1841 21675.71652 21941.82714 22764.68313 18893.99969 18579.24534 1.103378465 1.07659727 1.231462135 1.058347638 1.181058956 1.166662915 1.180985919 1.225274908 1.016941181 1 14.18140428 -13.52287864 0.040006038 0.163336286 1.637625461 0.675723706 0.045537699 246.0435144 0.785731025 25.18459186 8.181832106 3.00E-14 13.52287864 1.474289174 TKDGVVEITGKHEER ddPTM_HeLa_Curcumin_4h_R1 2 TKDGVVEITGKHEER 15 2 P04792 P04792 HSPB1 Heat shock protein beta-1 0 0 ; ; 60.157 0.01089 10201400 15656.7 10503.5 12629.2 13146.7 10692 19161.4 12374.3 10895.9 16348.8 14840.4 FALSE FALSE TRUE 14417.45567 11411.37574 13097.24926 13092.30244 10564.50488 15187.10965 12721.48955 14218.00975 14555.37754 15356.1028 0.938874652 0.743116655 0.852901901 0.85257976 0.687967841 0.98899505 0.82843217 0.925886596 0.94785622 1 13.9065245 -7.465002054 5.887791243 0.973640198 0.839990798 0.334132327 0.079995144 0.163396135 11.48644015 0.013280801 0.014927847 3.43E-08 7.465002054 -0.1336494 TKDIEDVFYK ddPTM_HeLa_Curcumin_4h_R1 2 TKDIEDVFYK 10 1 J3KTL2;Q07955;Q07955-3;Q07955-2;J3QQV5;J3KSW7 J3KTL2 SRSF1 Serine/arginine-rich splicing factor 1 0 0 ; ; 112.83 0.0021573 8268900 12871.6 10015.5 11073.1 11556.9 10111.8 12518.8 10537.6 10088.9 10769.9 8743.3 FALSE FALSE TRUE 11852.79928 10881.19519 11483.47883 11509.08061 9991.223389 9922.259764 10833.2567 13164.95917 9588.468915 9047.129024 1.310117193 1.202723556 1.269295353 1.272125177 1.104352924 1.096730215 1.197424804 1.455153246 1.059835544 1 13.14324433 -9.410111055 1.085051484 0.99725732 1.235639486 0.411424602 0.099024171 0.397132889 0.820864207 0.073225769 0.017715434 3.89E-10 9.410111055 0.238382166 TKDQPDGSSLS(ph)PAQS(ph)PSQSQPPAASSLR ddPTM_HeLa_Curcumin_4h_R1 2 TKDQPDGSSLSPAQSPSQSQPPAASSLR 28 1 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9;J3KSW8;Q6WCQ1-3 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 2 0 TKDQPDGS(0.001)S(0.009)LS(0.991)PAQS(0.525)PS(0.432)QS(0.042)QPPAASSLR;T(0.001)KDQPDGS(0.024)S(0.184)LS(0.794)PAQS(0.917)PS(0.07)QS(0.011)QPPAASSLR ; 128.04 5.48E-08 20159000 2946.9 2485.7 3294 3545.1 3493.4 3457.7 3520.4 3995.5 2965.2 2829.4 TRUE FALSE FALSE 2713.649755 2700.552832 3416.078538 3530.431316 3451.743487 2740.534044 3619.172949 5213.709557 2639.924979 2927.721439 0.92688113 0.922407711 1.166804496 1.205863122 1.178986307 0.936063796 1.236173941 1.78080793 0.901699507 1 11.51556258 -1.288130683 0.885910754 0.99594386 199.9999897 0.78772549 0.116112029 152.3859035 0.607328476 0.01927055 60908.02494 0.051507363 1.288130683 199.0040459 TKDQPDGSSLS(ph)PAQS(ph)PSQSQPPAASSLREPGLESK ddPTM_HeLa_Curcumin_4h_R1 1 TKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESK 35 2 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9;J3KSW8;Q6WCQ1-3 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 2 0 TKDQPDGSS(0.002)LS(0.848)PAQS(0.534)PS(0.527)QS(0.07)QPPAAS(0.008)S(0.008)LREPGLES(0.001)K 69.548 6.40E-06 53913000 2755.6 2226.2 2238.7 2063.3 2775.9 3114.5 2350.4 2884.1 2607.1 2289.4 TRUE FALSE FALSE 2537.491352 2418.622808 2321.668191 2054.762611 2742.799205 2468.517592 2416.345898 3763.448813 2321.107653 2368.95648 1.071143085 1.020965488 0.980038347 0.86737035 1.157809031 1.042027413 1.020004343 1.588652576 0.979801728 1 11.21003598 -4.261012072 24.91778164 1.026890513 1.588652753 0.854889484 0.070704924 8.847413868 515743.7463 0.009444511 0.074677144 5.48E-05 4.261012072 0.56176224 TKDQPDGSSLS(ph)PAQSPSQSQPPAASSLR ddPTM_HeLa_Curcumin_4h_R1 2 TKDQPDGSSLSPAQSPSQSQPPAASSLR 28 1 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9;J3KSW8;Q6WCQ1-3 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 TKDQPDGSS(0.003)LS(0.997)PAQSPSQSQPPAASSLR;TKDQPDGS(0.003)S(0.028)LS(0.926)PAQS(0.041)PS(0.001)QSQPPAASSLR ; 139.79 3.88E-10 27679000 6795.6 5819.5 6290.5 6203.1 6907.8 7290.5 5574.9 3787.8 6078.2 5435.8 TRUE FALSE FALSE 6257.721089 6322.511649 6523.631464 6177.433216 6825.428997 5778.368119 5731.31669 4942.682783 5411.436667 5624.693645 1.112544342 1.124063291 1.159819872 1.098270165 1.213475689 1.027321394 1.01895624 0.878747021 0.962085583 1 12.45755881 -4.295432533 1.807550542 1.080451317 0.823975686 0.449695646 0.070624915 0.624348369 2.14620087 0.010549869 0.26527668 5.06E-05 4.295432533 -0.256475632 TKDQPDGSSLS(ph)PAQSPSQSQPPAASSLREPGLESK ddPTM_HeLa_Curcumin_4h_R1 1 TKDQPDGSSLSPAQSPSQSQPPAASSLREPGLESK 35 2 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9;J3KSW8;Q6WCQ1-3 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 TKDQPDGS(0.002)S(0.013)LS(0.96)PAQS(0.01)PS(0.01)QS(0.003)QPPAASSLREPGLESK 80.583 2.72E-08 13927000 2113.8 1863.7 2074.8 1747.6 2285.4 2073.2 1609.5 906.88 1910.1 1744.3 TRUE FALSE FALSE 1946.4905 2024.789924 2151.693913 1740.368894 2258.148098 1643.19495 1654.658238 1183.383537 1700.566809 1804.914295 1.078439295 1.121820537 1.192130795 0.964239077 1.251110983 0.910400541 0.916751694 0.655645279 0.942187013 1 10.81771462 -4.310450826 1.396999191 1.061497926 0.522055705 0.616419364 0.099676341 0.536390256 0.980067201 0.013277735 0.394190042 4.89E-05 4.310450826 -0.539442221 TKDSGSIS(ph)LQETR ddPTM_HeLa_Curcumin_4h_R1 1 TKDSGSISLQETR 13 1 Q9H2G2-2;Q9H2G2 Q9H2G2-2 SLK STE20-like serine/threonine-protein kinase 1 0 TKDS(0.18)GS(0.18)IS(0.639)LQETR 219.97 9.16E-13 68905000 4408.5 2701.4 4204.8 4986.9 3887.4 4158.4 3168.8 1189.7 3229.6 2735.9 TRUE FALSE FALSE 4059.562573 2934.896979 4360.633587 4966.265529 3841.045294 3295.900965 3257.708 1552.434053 2875.32096 2830.972321 1.433981725 1.036709881 1.540330703 1.754261422 1.356793659 1.164229315 1.150738202 0.548374861 1.015665515 1 11.46708193 -4.116814875 1.877163616 1.26997558 0.10888318 0.472454987 0.233253356 1.02533381 2.691332259 0.037286384 2.345889397 7.64E-05 4.116814875 -1.1610924 TKEAVLLLK ddPTM_HeLa_Curcumin_4h_R1 1 TKEAVLLLK 9 1 P36578;H3BM89;H3BTP7 P36578 RPL4 60S ribosomal protein L4 0 0 87.806 0.0054572 0 2602.5 1835.8 2124.8 1859.4 2176.8 3129.3 2485.3 2419.5 2313.4 2322.6 FALSE FALSE TRUE 2396.509379 1994.478372 2203.546957 1851.706295 2150.843082 2480.247906 2555.030829 3157.194412 2059.625808 2403.310177 0.997170237 0.82988804 0.916879968 0.77048161 0.894950266 1.032013233 1.063129867 1.313685783 0.856995417 1 11.23080714 -4.210017794 1.581197962 0.957471153 1.475087844 0.653591199 0.085873758 0.670627086 1.412799445 0.013498421 0.553747886 6.17E-05 4.210017794 0.517616691 LPTEMEGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 3 LPTEMEGKK 9 1 Q9NWX6 Q9NWX6 THG1L Probable tRNA(His) guanylyltransferase 0 1 ;; LPTEMEGK(1)K;LPTEMEGK(1)K;LPTEMEGK(1)K 99.815 0.0033506 43951000 6241.8 5797.3 6434 6120.9 7843.8 8854.2 9039.1 8664.8 6042.8 5230.5 FALSE TRUE FALSE 5747.754944 6298.39278 6672.4497 6095.573338 7750.267808 7017.739113 9292.712819 11306.65763 5379.919958 5412.259486 1.061988059 1.163727053 1.232839947 1.126252973 1.431983782 1.296637593 1.716974739 2.089082695 0.994024764 1 12.40201529 -1 0.384443054 1.021413964 16.96737656 0.938568176 0.082435408 8.588408804 0.103678372 0.019568144 103.6259254 0.1 1 15.9459626 up TKEVYELLDS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 2 TKEVYELLDSPGK 13 1 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 0 TKEVYELLDS(1)PGK;TKEVYELLDS(1)PGK ; 106.44 0.0021035 996440000 12177.9 10407.4 11016.6 12071.9 12666.5 17969.4 18230.4 7665.9 11508.5 9183.4 TRUE FALSE FALSE 11214.00636 11306.96928 11424.88489 12021.94968 12515.46026 14242.34388 18741.89596 10003.19762 10246.04634 9502.522466 1.180108377 1.18989135 1.202300224 1.265132465 1.317067158 1.498796128 1.972307461 1.052688658 1.078244895 1 13.21409482 -6.081174984 0.527865565 1.057307374 1.576976735 0.3483724 0.217126315 0.770707681 0.385959384 0.052837416 0.180446833 8.30E-07 6.081174984 0.519669361 TKEVYELLDS(ph)PGKVLLQSK ddPTM_HeLa_Curcumin_4h_R1 2 TKEVYELLDSPGKVLLQSK 19 2 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 1 0 TKEVYELLDS(0.995)PGKVLLQS(0.005)K;T(0.001)KEVYELLDS(0.839)PGKVLLQS(0.16)K ; 69.081 0.0031656 661110000 9458 7162 6703.5 7946 5882.5 15413.6 12682.9 5472.4 10204.3 8550.6 TRUE FALSE FALSE 8709.38932 7781.051367 6951.937607 7913.121557 5812.355029 12216.64561 13038.74804 7140.909568 9084.91382 8847.732714 0.984363972 0.879440148 0.78573097 0.894367158 0.65693158 1.380765673 1.473682407 0.807089206 1.026806993 1 13.11109209 -5.242837228 24.95688259 0.94091344 1.245829426 0.351842043 0.196480923 700.452848 939734.8646 0.026610792 0.067709335 5.72E-06 5.242837228 0.304915986 TKEVYELLDSPGK ddPTM_HeLa_Curcumin_4h_R1 1 TKEVYELLDSPGK 13 1 E9PBS1;P22234;P22234-2 E9PBS1 PAICS Multifunctional protein ADE2;Phosphoribosylaminoimidazole-succinocarboxamide synthase;Phosphoribosylaminoimidazole carboxylase 0 0 102.33 0.0025432 2157100 4355.4 3595.6 3521.4 4242.9 3702.7 4262.2 3745.2 3842.8 4933.5 4409.7 FALSE FALSE TRUE 4010.665494 3906.387642 3651.906182 4225.344004 3658.547721 3378.171675 3850.280232 5014.45203 4392.307393 4562.936747 0.878965832 0.8561126 0.80034118 0.926014152 0.801796721 0.740350319 0.843816263 1.098952782 0.962605365 1 12.15574694 -8.799459485 0.700261156 1.000467892 0.858729518 0.186795402 0.091936491 0.780842691 0.725522936 0.059013553 0.020139245 1.59E-09 8.799459485 -0.141738374 TKEYVSNDAAQS(ph)DDEEK ddPTM_HeLa_Curcumin_4h_R1 1 TKEYVSNDAAQSDDEEK 17 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 T(0.002)KEYVSNDAAQS(0.998)DDEEK 97.488 0.001161 9783600 2118.6 2348.6 2473.9 1960.1 2612.9 2874.3 2469.1 2352.8 1999.5 2235.4 TRUE FALSE FALSE 1950.910574 2551.602519 2565.58491 1951.989626 2581.742874 2278.13778 2538.376301 3070.157889 1780.159853 2313.079984 0.843425471 1.103119017 1.109163941 0.843891971 1.116149417 0.984893647 1.097401006 1.327302951 0.769605835 1 11.17559944 -1.000000001 0.557708137 0.946387342 18.21352015 0.496779587 0.112398048 74.79507423 0.610383648 0.019352714 1558.103501 0.1 1.000000001 17.26713281 TKEYVSNDAAQS(ph)DDEEKLQSQPTDTDGGR ddPTM_HeLa_Curcumin_4h_R1 3 TKEYVSNDAAQSDDEEKLQSQPTDTDGGR 29 2 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 TKEYVSNDAAQS(0.999)DDEEKLQSQPTDTDGGR;T(0.002)KEY(0.002)VS(0.001)NDAAQS(0.991)DDEEKLQS(0.003)QPT(0.001)DTDGGR;TKEYVSNDAAQS(0.997)DDEEKLQS(0.002)QPTDTDGGR ;; 86.248 1.10E-06 558210000 8256.3 6600.7 6895.57 6826.56 7363.21 8426.38 6646.32 7211.16 8383.4 7818.7 TRUE FALSE FALSE 7602.805143 7171.235096 7151.12589 6798.313504 7275.40853 6678.653803 6832.797852 9409.809488 7463.761994 8090.399243 0.939731763 0.886388283 0.883902719 0.840293946 0.899264463 0.825503613 0.844556325 1.163083453 0.922545572 1 12.98199518 -8.001811787 0.979955706 0.98807435 0.897760217 0.026639663 0.093450308 0.633973947 1.293700252 0.024485825 0.019320589 9.96E-09 8.001811787 -0.090314133 TKFAS(ph)DDEHDEHDENGATGPVK ddPTM_HeLa_Curcumin_4h_R1 2 TKFASDDEHDEHDENGATGPVK 22 1 P05455 P05455 SSB Lupus La protein 1 0 T(0.383)KFAS(0.615)DDEHDEHDENGAT(0.002)GPVK;T(0.227)KFAS(0.773)DDEHDEHDENGATGPVK ; 58.812 0.0042097 180879000 9815.2 8926.2 9585.9 9248.1 10770.3 10421.7 9343.3 7257.9 9779.6 9710.3 TRUE FALSE FALSE 9038.316563 9697.740954 9941.161887 9209.833813 10641.87121 8260.121943 9605.447852 9470.800299 8706.802347 10047.7322 0.899537964 0.96516714 0.989393595 0.916608208 1.059131652 0.822088186 0.955981674 0.942580884 0.866544029 1 13.2945823 -6.534154098 0.006187437 1.887473421 1.68E-05 0 0.067448206 11232.02545 34.33691146 5174.072547 5298.876205 2.92E-07 6.534154098 -1.887456613 TKFAS(ph)DDEHDEHDENGATGPVKR ddPTM_HeLa_Curcumin_4h_R1 1 TKFASDDEHDEHDENGATGPVKR 23 2 P05455 P05455 SSB Lupus La protein 1 0 T(0.256)KFAS(0.744)DDEHDEHDENGATGPVKR 71.265 0.0011246 13229000 1362.4 1110.2 1362.9 1344.4 960.21 1661.9 857.75 1044.2 1894.4 1397.8 TRUE FALSE FALSE 1254.564602 1206.160741 1413.410273 1338.837229 948.7601229 1317.203207 881.8161565 1362.571773 1686.58906 1446.373446 0.867386363 0.833920689 0.977209777 0.92565114 0.655957924 0.910693715 0.609673912 0.942060833 1.166081322 1 10.49822438 -13.52287875 0.075900721 1.617297285 0.627730511 0.359170812 0.123325978 175.4412446 1.027289816 18.50626552 2.281379826 3.00E-14 13.52287875 -0.989566774 TKFICVTPTTCSNTIDLPMS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 TKFICVTPTTCSNTIDLPMSPR 22 1 G8JLH9;P40763-2;P40763 G8JLH9 STAT3 Signal transducer and activator of transcription;Signal transducer and activator of transcription 3 1 0 TKFICVTPTTCSNT(0.002)IDLPMS(0.998)PR;TKFICVTPTT(0.002)CS(0.021)NT(0.017)IDLPMS(0.96)PR ; 88.708 0.00018114 16314000 1854.46 1400.69 1153.91 1233.77 936.18 2008.92 1647.93 1800.21 2184.25 1789.72 TRUE FALSE FALSE 1707.677534 1521.759402 1196.67492 1228.664987 925.0166649 1592.247347 1694.166481 2349.085742 1944.64324 1851.912637 0.922115601 0.821723105 0.646183246 0.663457316 0.499492604 0.859785346 0.914819872 1.268464665 1.050072882 1 10.85480033 -7.387240559 2.377266298 0.969070833 0.791617862 0.149778163 0.194511744 0.446602922 4.779786259 0.036975739 0.041882109 4.10E-08 7.387240559 -0.177452971 TKPLATTQPAKTS(ph)TSK ddPTM_HeLa_Curcumin_4h_R1 2 TKPLATTQPAKTSTSK 16 2 E7EVA0;P27816;P27816-6;P27816-5;P27816-4;B5MEG9;H7C4C5 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 TKPLATTQPAKT(0.29)S(0.483)T(0.168)S(0.059)K;TKPLATTQPAKT(0.108)S(0.763)T(0.108)S(0.022)K ; 94.188 0.0031899 37928000 4225.5 3282.3 3285 3898.2 3347.6 7101.9 6724 1721.7 4082.5 3154.5 TRUE FALSE FALSE 3891.047216 3566.007386 3406.74499 3882.070281 3307.682056 5628.885885 6912.657343 2246.638404 3634.659964 3264.11864 1.192066725 1.092487063 1.04369521 1.189316538 1.01334615 1.724473435 2.117771474 0.688283317 1.113519564 1 11.67247778 -5.266913295 24.9310231 1.092292971 1.570935622 0.238212596 0.337432924 368.3752658 1677773.994 0.043620702 0.100214075 5.41E-06 5.266913295 0.478642651 TKPLTPS(ph)IGAK ddPTM_HeLa_Curcumin_4h_R1 1 TKPLTPSIGAK 11 1 Q14004-2;Q14004;A0A2R8Y7W5;A0A2R8Y4Z0;A0A2R8Y7Y0;A0A2R8YCQ1;A0A2R8YD28;A0A2R8YF61 Q14004-2 CDK13 Cyclin-dependent kinase 13 1 0 T(0.002)KPLT(0.113)PS(0.885)IGAK 68.44 0.018373 58567000 4110 3014.8 3893.8 4349.4 3430.8 4585.7 4944.6 4425.8 4281.5 3577 TRUE FALSE FALSE 3784.689163 3275.385878 4038.107653 4331.403335 3389.889951 3634.574129 5083.332168 5775.206046 3811.830162 3701.300484 1.022529562 0.88492839 1.090996981 1.170238232 0.915864563 0.981972186 1.373390837 1.560318075 1.02986239 1 11.85381655 -4.634284886 3.454286563 1.010377135 1.529349323 0.848271637 0.078542059 0.059131751 1.316161368 0.010751132 0.050376082 2.32E-05 4.634284886 0.518972188 TKPTQAAGPS(ph)SPQKPPT(ph)PEETK ddPTM_HeLa_Curcumin_4h_R1 1 TKPTQAAGPSSPQKPPTPEETK 22 2 F5H8D7;P18887 F5H8D7 XRCC1 DNA repair protein XRCC1 2 0 T(0.001)KPT(0.001)QAAGPS(0.563)S(0.563)PQKPPT(0.763)PEET(0.11)K 50.776 0.0095484 65667000 3518.9 2787 3850 3570 3355.4 3190.3 3159.7 3695.1 3002 2787.5 TRUE FALSE FALSE 3240.375352 3027.895861 3992.684387 3555.228286 3315.389046 2528.595818 3248.352678 4821.71898 2672.688111 2884.365418 1.123427473 1.049761533 1.38425054 1.232585949 1.149434474 0.87665585 1.126193186 1.671674106 0.926612174 1 11.49403823 -4.266108787 5.293192322 1.088594664 1.69414548 0.606275243 0.139196636 0.07577519 7.456809393 0.019032355 0.165660737 5.42E-05 4.266108787 0.605550816 TKPTQAAGPS(ph)SPQKPPTPEETK ddPTM_HeLa_Curcumin_4h_R1 2 TKPTQAAGPSSPQKPPTPEETK 22 2 F5H8D7;P18887 F5H8D7 XRCC1 DNA repair protein XRCC1 1 0 TKPTQAAGPS(0.497)S(0.497)PQKPPT(0.005)PEETK;T(0.002)KPT(0.016)QAAGPS(0.746)S(0.211)PQKPPT(0.022)PEET(0.002)K ; 60.347 0.0027505 519780000 10562.3 7826.1 9118.1 8527 9053.3 10889.3 8791.3 6497.1 9999.1 9073.1 TRUE FALSE FALSE 9726.28281 8502.553212 9456.024807 8491.717533 8945.34531 8630.736432 9037.960217 8478.035881 8902.223747 9388.38955 1.035990545 0.905645549 1.007204138 0.904491392 0.952809346 0.919298926 0.962674181 0.903034097 0.948216273 1 13.19666199 -7.26786878 24.99159517 1.016995536 0.938921187 0.275140564 0.03842589 252.3740573 980996.0192 0.005100562 0.00590276 5.40E-08 7.26786878 -0.078074349 TKPTQAAGPSS(ph)PQKPPT(ph)PEETK ddPTM_HeLa_Curcumin_4h_R1 1 TKPTQAAGPSSPQKPPTPEETK 22 2 F5H8D7;P18887 F5H8D7 XRCC1 DNA repair protein XRCC1 2 0 T(0.005)KPT(0.003)QAAGPS(0.412)S(0.804)PQKPPT(0.651)PEET(0.125)K 47.822 0.013147 65291000 3569.5 3093.4 3483.1 3243.2 3754.5 3816.6 3676 3728.8 3217.8 3190.6 TRUE FALSE FALSE 3286.970308 3360.779712 3612.18675 3229.780498 3709.73004 3024.994138 3779.138667 4865.693955 2864.815391 3301.473113 0.995607172 1.017963678 1.094113636 0.978284659 1.123659019 0.916255876 1.144682552 1.473794815 0.867738519 1 11.68889418 -4.329309741 2.869335792 1.009438353 1.521495821 0.797988497 0.072111797 0.079251906 0.977483681 0.007093387 0.086332475 4.68E-05 4.329309741 0.512057467 TKPYIQVDIGGGQTK ddPTM_HeLa_Curcumin_4h_R1 1 TKPYIQVDIGGGQTK 15 1 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 0 127.2 0.00065622 6826700 9220.1 7489.3 8166.4 8289.4 8154.1 10111 7836.6 5694.6 9028.1 7992.1 FALSE FALSE TRUE 8490.319356 8136.64172 8469.053968 8255.100659 8056.867683 8013.864626 8056.473905 7430.857325 8037.740017 8269.82488 1.026662533 0.983895287 1.024091089 0.998219524 0.974248887 0.969048891 0.97420127 0.898550747 0.97193594 1 13.01364106 -2.074933783 0.490722616 1.01162152 9.44E-10 0.668864825 0.019692183 9.56993171 0.273481155 0.003273623 8.839062806 0.008415234 2.074933783 -1.011621519 S(ph)PSPAHLPDDPKVAEK ddPTM_HeLa_Curcumin_4h_R1 1 SPSPAHLPDDPKVAEK 16 1 A0A087X183;H0Y4V9;Q92615;H0Y641 A0A087X183 LARP4B La-related protein 4B 1 0 S(0.5)PS(0.5)PAHLPDDPKVAEK 73.688 0.0076061 65919000 14816 11858 11047 12048 10103 15812 9139.7 3509.6 17983 14450 TRUE FALSE FALSE 13643.29797 12882.95268 11456.41154 11998.14857 9982.528323 12532.41296 9396.135384 4579.660884 16010.30989 14952.13642 0.912464786 0.861612837 0.766205659 0.802437072 0.667632239 0.838168714 0.628414236 0.306288062 1.07077072 1 13.86806402 -4.078238113 0.318945037 0.984530249 6.50E-18 0.792543711 0.093449696 2.630644176 0.175737024 0.03500165 1.025362489 8.35E-05 4.078238113 -0.984530249 down TKSPT(ph)DDEVTPSAVVR ddPTM_HeLa_Curcumin_4h_R1 1 TKSPTDDEVTPSAVVR 16 1 A0A1B0GUN5;Q5VTI5;Q9Y2H5 A0A1B0GUN5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 0 TKS(0.128)PT(0.787)DDEVT(0.08)PS(0.004)AVVR 110.6 0.01519 14728000 1754.1 1507.2 1695.6 1869 1634.3 1870.9 1111 1114.3 2091.4 1676.5 TRUE FALSE FALSE 1615.261134 1637.475652 1758.440428 1861.266573 1614.81204 1482.854251 1142.17167 1454.04494 1861.978652 1734.75825 0.931115983 0.943921524 1.013651572 1.072925621 0.930857103 0.854790142 0.658403942 0.838183038 1.073336099 1 10.76051891 -5.120791214 2.792674541 0.975171049 0.748989442 0.692097286 0.065863367 0.105861096 1.581056319 0.008359122 0.025569948 7.57E-06 5.120791214 -0.226181607 TKVGDGDLS(ph)AEEIPENEVSLR ddPTM_HeLa_Curcumin_4h_R1 2 TKVGDGDLSAEEIPENEVSLR 21 1 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 0 TKVGDGDLS(1)AEEIPENEVSLR;T(0.003)KVGDGDLS(0.997)AEEIPENEVSLR ; 75.044 0.00090122 16113400 3839.7 3277.2 3429.6 3349.2 3539.8 4609.1 2722.1 1856.55 3941.8 3788.9 TRUE FALSE FALSE 3535.783693 3560.466565 3556.703993 3335.341898 3497.590197 3653.120705 2798.4748 2422.603548 3509.394402 3920.563993 0.901855881 0.908151626 0.907191924 0.850730126 0.892114044 0.931784486 0.713793935 0.617922205 0.895124887 1 11.93684549 -3.504850703 0.57253386 0.947352137 2.17E-36 0.788237053 0.048992027 2.518624635 0.301990109 0.010089684 1.930230766 0.000312715 3.504850703 -0.947352137 TLAPTWEELSK ddPTM_HeLa_Curcumin_4h_R1 1 TLAPTWEELSK 11 0 Q8NBS9-2;Q8NBS9 Q8NBS9-2 TXNDC5 Thioredoxin domain-containing protein 5 0 0 123.79 0.0016078 806070 402.67 418.83 339.13 383.05 435.54 257.1 374.35 368.18 340.12 202.86 FALSE FALSE TRUE 370.7982446 455.0317989 351.6984561 381.4650406 430.34647 203.7745619 384.8532535 480.4363871 302.8096869 209.9093699 1.766468285 2.167753632 1.675477642 1.817284482 2.050153693 0.970774015 1.833425795 2.288780093 1.442573464 1 7.713622757 -8.983941471 0.773981725 0.992211736 1.806134165 0.273701494 0.362840835 0.487076782 0.53087357 0.230518789 0.070111653 1.04E-09 8.983941471 0.813922428 TLDFDPLLS(ph)PASPK ddPTM_HeLa_Curcumin_4h_R1 1 TLDFDPLLSPASPK 14 0 Q53H80 Q53H80 AKIRIN2 Akirin-2 1 0 TLDFDPLLS(0.83)PAS(0.17)PK 197.06 2.38E-06 136180000 8490.2 6963.9 7461.3 7784.6 7745.9 11717 8953.5 2602.3 8611.6 7228.2 TRUE FALSE FALSE 7818.191711 7565.828485 7737.822342 7752.389388 7653.535202 9286.762122 9204.711113 3395.72929 7666.929025 7479.379412 1.04529952 1.011558322 1.034554061 1.036501688 1.023284791 1.241648753 1.230678457 0.454012172 1.025075558 1 12.86870285 -4.250327063 24.78753997 1.048293619 0.454011784 0.817065539 0.087082455 496.4036263 1107272.952 0.012829336 0.256613979 5.62E-05 4.250327063 -0.594281835 TLDFDPLLSPAS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 TLDFDPLLSPASPK 14 0 Q53H80 Q53H80 AKIRIN2 Akirin-2 1 0 TLDFDPLLSPAS(1)PK 293.42 3.36E-77 136740000 6897.2 6008.8 6501.9 5972.4 5857.6 9249.6 7595.4 2495.9 6847.2 6215.4 TRUE FALSE FALSE 6351.279342 6528.173897 6742.866134 5947.687791 5787.751946 7331.128696 7808.506482 3256.88842 6096.079291 6431.384687 0.987544619 1.015049513 1.048431475 0.924791173 0.899923147 1.139898957 1.214125241 0.506405475 0.947864198 1 12.65091367 -4.246353665 24.982586 1.008842597 0.506405115 0.737341362 0.091706495 1093.226805 1810401.612 0.012298896 0.389552388 5.67E-05 4.246353665 -0.502437482 TLDFDPLLSPAS(ph)PKR ddPTM_HeLa_Curcumin_4h_R1 2 TLDFDPLLSPASPKR 15 1 Q53H80 Q53H80 AKIRIN2 Akirin-2 1 0 TLDFDPLLS(0.295)PAS(0.705)PKR;TLDFDPLLS(0.211)PAS(0.789)PKR ; 96.153 0.0024748 123767000 8211.6 6179.8 7116 7645 7430.9 12666.9 9320.6 3144 7680.2 6818.3 TRUE FALSE FALSE 7561.643195 6713.954375 7379.72522 7613.367016 7342.291371 10039.64215 9582.110951 4102.591127 6837.701275 7055.235417 1.071777588 0.951627264 1.045992768 1.079108855 1.040686942 1.423005975 1.35815609 0.581495993 0.96916699 1 12.78447851 -5.475817272 24.98568139 1.032791775 1.159151907 0.032136603 0.214116443 869.7162668 461745.1265 0.028263562 0.063197153 3.34E-06 5.475817272 0.126360132 TLDPLVNTS(ph)S(ph)LIMR ddPTM_HeLa_Curcumin_4h_R1 2 TLDPLVNTSSLIMR 14 0 J3KNS1;Q9UPW5 J3KNS1 AGTPBP1 Cytosolic carboxypeptidase 1 2 0 T(0.257)LDPLVNT(0.269)S(0.494)S(0.98)LIMR;T(0.004)LDPLVNT(0.463)S(0.608)S(0.925)LIMR ; 94.023 0.009545 2656508000 3184.5 2940 2908.5 2984 2746.2 3231.3 2914.1 2342.8 2990.4 2618.4 TRUE FALSE FALSE 2932.443465 3194.1205 3016.291569 2971.652999 2713.453359 2561.091956 2995.861803 3057.108935 2662.360602 2709.389205 1.0823264 1.17890796 1.113273635 1.096798124 1.001500026 0.945265431 1.105733277 1.128338789 0.98264236 1 11.40375194 -9.048360157 1.040415304 1.003827838 1.07868615 0.239851295 0.062653647 0.706835018 1.470089414 0.03423806 0.012594537 8.95E-10 9.048360157 0.074858312 TLDSGTSEIVKS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 TLDSGTSEIVKSPR 14 1 Q9H501 Q9H501 ESF1 ESF1 homolog 1 0 TLDSGTSEIVKS(1)PR 146.84 0.0056665 23178000 1274.8 1070.1 1178.1 1244.4 1200.3 1362.6 1089.7 769.34 1304.2 1154.1 TRUE FALSE FALSE 1173.898235 1162.594676 1221.761422 1239.251003 1185.987206 1079.9814 1120.274049 1003.908224 1161.132523 1194.204889 0.98299567 0.973530327 1.023075214 1.03772059 0.9931187 0.90435185 0.938091997 0.840649903 0.972305953 1 10.22183466 -4.688260993 1.150773293 0.996159562 0.839353265 0.738868135 0.028436609 0.329061382 0.56209931 0.004237355 0.051490188 2.05E-05 4.688260993 -0.156806297 TLEAEFNSPS(ph)PPTPEPGEGPR ddPTM_HeLa_Curcumin_4h_R1 1 TLEAEFNSPSPPTPEPGEGPR 21 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 0 TLEAEFNS(0.013)PS(0.986)PPTPEPGEGPR 183.21 4.75E-10 11956000 2627.4 2213.6 2135.7 1886 2270.6 3074.7 2297.3 679.08 2285.9 2112.2 TRUE FALSE FALSE 2419.438518 2404.93372 2214.850921 1878.196232 2243.524578 2436.972561 2361.756055 886.1283659 2035.142489 2185.598793 1.106991148 1.100354616 1.013384034 0.859350874 1.026503394 1.115013684 1.080599085 0.40543963 0.931160145 1 11.09381288 -4.259425583 24.91480709 1.043767744 0.405439401 0.844120246 0.079660978 46.0264303 569397.2338 0.010858823 0.095295845 5.50E-05 4.259425583 -0.638328342 YDEIFYNLAPADGKLS(ph)GSK ddPTM_HeLa_Curcumin_4h_R1 2 YDEIFYNLAPADGKLSGSK 19 1 Q9NZN4-2;Q9NZN4 Q9NZN4-2 EHD2 EH domain-containing protein 2 1 0 YDEIFYNLAPADGKLS(0.954)GS(0.046)K;YDEIFYNLAPADGKLS(0.898)GS(0.102)K ; 130.83 6.86E-05 304250000 6194.1 4938.5 5688.5 5036.3 6274 7687.6 6751.7 8922.9 5159.8 4756.5 TRUE FALSE FALSE 5703.830449 5365.361934 5899.320814 5015.461125 6199.186648 6093.105103 6941.134531 11643.45113 4593.782849 4921.788021 1.158893968 1.090124547 1.198613347 1.019032332 1.259539546 1.237986089 1.410287176 2.36569537 0.933356502 1 12.26496681 -1.602531271 0.912876618 1.088170743 200 0.946878941 0.089866611 38.77530514 0.266427704 0.013116218 15833.86762 0.024972886 1.602531271 198.9118293 up TLEEDEEELFK ddPTM_HeLa_Curcumin_4h_R1 4 TLEEDEEELFK 11 0 P43487-2;P43487;F6WQW2;C9JJ34;C9JDM3 P43487-2 RANBP1 Ran-specific GTPase-activating protein 0 0 ;;; ;;; 201.61 1.10E-08 88266120 6352.68 4862.35 5878.79 6097.33 5524.65 6965.97 5639.86 5526.57 6688.15 5397.46 FALSE FALSE TRUE 5849.858675 5282.629868 6096.663129 6072.100864 5458.772157 5521.149299 5798.099293 7211.595752 5954.476678 5585.021333 1.047419218 0.945856704 1.09160964 1.087211758 0.977395041 0.98856369 1.038151682 1.291238712 1.066151107 1 12.44734708 -4.263318344 4.878617595 1.021647387 1.305179192 0.748659181 0.045948191 0.059918967 4.203102464 0.006012614 0.057243266 5.45E-05 4.263318344 0.283531805 TLEEEAK ddPTM_HeLa_Curcumin_4h_R1 2 TLEEEAK 7 0 P35579 P35579 MYH9 Myosin-9 0 0 ; ; 127.12 0.0088051 15789500 6565.5 7776.9 7152 5927.2 5365.6 7512.4 5509.9 4668.1 5931.6 6644.5 FALSE FALSE TRUE 6045.833747 8449.100583 7417.059412 5902.674817 5301.618724 5954.243558 5664.492965 6091.382201 5280.91832 6875.39588 0.879343365 1.228889322 1.078782886 0.858521447 0.77110014 0.866021922 0.823878808 0.885968213 0.768089345 1 12.74722707 -6.088192768 8.189491935 0.976700278 0.835077356 0.29092362 0.116333588 0.319838154 27.05060095 0.016496236 0.027432314 8.16E-07 6.088192768 -0.141622922 TLEEEAKTHEAQIQEMR ddPTM_HeLa_Curcumin_4h_R1 1 TLEEEAKTHEAQIQEMR 17 1 P35579 P35579 MYH9 Myosin-9 0 0 79.471 0.002741 13248000 2056.2 1719.4 1504.7 1769.8 1397.2 2078.6 1679.4 1469.7 2329.6 1980.8 FALSE FALSE TRUE 1893.4496 1868.017275 1560.465506 1762.477037 1380.539303 1647.474929 1726.519444 1917.804764 2074.048708 2049.632653 0.923799491 0.911391255 0.761339113 0.859898984 0.673554503 0.803790341 0.842355552 0.935682188 1.011912406 1 11.00114965 -7.275298131 1.11988171 0.975091308 0.809311445 0.537288671 0.068548918 0.260429689 0.636480612 0.014440302 0.017047479 5.31E-08 7.275298131 -0.165779863 TLEEVVMAEEEDEGTDRPGS(ph)PA ddPTM_HeLa_Curcumin_4h_R1 2 TLEEVVMAEEEDEGTDRPGSPA 22 1 F8WC89;A6NKF1 F8WC89 SAC3D1 SAC3 domain-containing protein 1 1 0 TLEEVVMAEEEDEGT(0.009)DRPGS(0.991)PA;TLEEVVMAEEEDEGT(0.025)DRPGS(0.975)PA ; 95.444 0.00049206 8262000 4250.8 3310.1 3606 3832.2 3675 4132.3 2887.61 2630.59 4901.8 3790.4 TRUE FALSE FALSE 3914.344695 3596.210294 3739.641532 3816.343372 3631.178025 3275.214399 2968.628565 3432.644781 4364.084804 3922.116118 0.998018564 0.916905616 0.953475476 0.973031715 0.925821142 0.835063089 0.756894614 0.875202232 1.112686283 1 11.93741653 -5.417957873 1.873891876 0.987717828 0.809784115 0.662872252 0.054235666 0.112670206 0.766371102 0.005738078 0.016353762 3.82E-06 5.417957873 -0.177933713 TLEGELHDLR ddPTM_HeLa_Curcumin_4h_R1 7 TLEGELHDLR 10 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;H0YAB0;P02545-2;Q3BDU5;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ;;;;;; ;;;;;; 181.87 0.00021614 351184800 46212.3 36316 39707.6 40502.1 40226.7 47939.6 36137.6 31096.8 45009.9 40173.9 FALSE FALSE TRUE 42554.54769 39454.99322 41179.19859 40334.51304 39747.02288 37996.38657 37151.5238 40578.07117 40072.42658 41569.94003 1.023685568 0.949123169 0.990600385 0.970280761 0.956148189 0.914035155 0.893711267 0.976139757 0.96397605 1 15.34325305 -6.188191534 0.796544884 1.009899418 0.924728213 0.324449567 0.030168117 0.310881258 0.385197474 0.005168835 0.012972486 6.48E-07 6.188191534 -0.085171205 TLENQS(ph)HETLER ddPTM_HeLa_Curcumin_4h_R1 2 TLENQSHETLER 12 0 P48681 P48681 NES Nestin 1 0 TLENQS(0.999)HETLER;TLENQS(1)HETLER ; 99.711 0.0034823 6201100 2790 2414.7 2273.25 2284.3 2957.7 3821.6 2765.1 2162.86 2728.5 2727.9 TRUE FALSE FALSE 2569.168556 2623.415908 2357.498645 2274.848172 2922.431359 3028.957082 2842.681264 2822.306057 2429.190376 2822.694322 0.91018306 0.929401348 0.835194455 0.805913752 1.035333984 1.073073006 1.007080803 0.999862449 0.860592788 1 11.46285719 S(ph)LQQLAEER ddPTM_HeLa_Curcumin_4h_R1 1 SLQQLAEER 9 0 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 1 0 S(1)LQQLAEER 114.56 0.0076765 8442200 527.23 459.16 572.1 586.07 676.18 666.71 610.7 816.36 596.84 488.47 TRUE FALSE FALSE 485.4991892 498.8477444 593.3025293 583.6449976 668.1169951 528.4268306 627.8345984 1065.264406 531.3681452 505.4442961 0.960539456 0.986949004 1.17382377 1.154716755 1.321841003 1.045469965 1.242143997 2.10758023 1.051289231 1 8.981408295 -1.599979287 0.944429825 1.019991398 199.9999987 0.867451182 0.116934115 81.98133721 0.505223391 0.019612154 34761.18165 0.025120062 1.599979287 198.9800073 up TLENSPISSCDT(ph)S(ph)DTEGPVPVNSAAVLKK ddPTM_HeLa_Curcumin_4h_R1 1 TLENSPISSCDTSDTEGPVPVNSAAVLKK 29 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 2 0 TLENS(0.011)PIS(0.209)S(0.208)CDT(0.681)S(0.681)DT(0.21)EGPVPVNSAAVLKK 116.35 1.68E-08 0 910.39 667.19 379.11 642.29 697.03 935.56 757.87 614.4 694.94 643.51 TRUE FALSE FALSE 838.3316709 724.8589307 393.1601501 639.6323742 688.7183725 741.5143101 779.1337925 801.7277317 618.7068207 665.8719246 1.258998375 1.088586114 0.590444101 0.960593698 1.034310574 1.113599001 1.170095575 1.204026934 0.929167904 1 9.379100902 -5.339692891 0.003329613 0.941144435 1.220783763 0 0.184649339 3507697.389 2781.15132 114986.1606 118604.7177 4.57E-06 5.339692891 0.279639329 TLENSPISSCDTS(ph)DTEGPVPVNSAAVLKK ddPTM_HeLa_Curcumin_4h_R1 2 TLENSPISSCDTSDTEGPVPVNSAAVLKK 29 1 Q8N556;Q8N556-2 Q8N556 AFAP1 Actin filament-associated protein 1 1 0 TLENSPIS(0.001)S(0.004)CDT(0.192)S(0.786)DT(0.017)EGPVPVNSAAVLKK;TLENSPISSCDT(0.033)S(0.484)DT(0.484)EGPVPVNSAAVLKK ; 112.39 4.71E-11 109870000 8589 6604.2 7771 8488.5 7351.2 9296.6 5957.3 4961.6 10465.2 8327.3 TRUE FALSE FALSE 7909.171587 7175.03762 8059.000096 8453.376836 7263.541741 7368.380366 6124.445805 6474.369 9317.193743 8616.673055 0.917891573 0.832692337 0.935279782 0.981048809 0.8429636 0.85513055 0.710766878 0.75137689 1.081298279 1 13.07291523 -2.072875382 0.23445671 0.986634936 9.10E-12 0.681514553 0.061267022 12.39563482 0.235912887 0.036321047 4.295595409 0.008455214 2.072875382 -0.986634936 TLEPVKPPTVPNDYMT(ph)SPAR ddPTM_HeLa_Curcumin_4h_R1 1 TLEPVKPPTVPNDYMTSPAR 20 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 0 TLEPVKPPT(0.002)VPNDY(0.001)MT(0.499)S(0.499)PAR 71.143 0.004935 111230000 992.65 981.46 1091.7 1168.2 874.6 1089.9 1099.1 449.62 1078.6 772.79 TRUE FALSE FALSE 914.0807051 1066.293029 1132.159362 1163.366298 864.1709662 863.8424543 1129.937788 586.7070682 960.2802785 799.644395 1.143109 1.333459017 1.415828548 1.454854564 1.080694083 1.080283261 1.413050345 0.733709974 1.200884149 1 9.64321476 -8.089284528 1.271464566 1.032835143 1.225640157 0.016760253 0.21310695 0.554919896 1.854050671 0.050610576 0.040761431 8.14E-09 8.089284528 0.192805015 TLEPVKPPTVPNDYMTS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 2 TLEPVKPPTVPNDYMTSPAR 20 1 A0A0A0MRT6;Q8IZP0-2;Q8IZP0-4;Q8IZP0-3;Q8IZP0-5;Q8IZP0-6;Q8IZP0-9;Q8IZP0-12;Q8IZP0;B6VEX4;Q8IZP0-11;Q8IZP0-10;Q8IZP0-8;Q8IZP0-7 A0A0A0MRT6 ABI1 Abl interactor 1 1 0 TLEPVKPPTVPNDYMT(0.069)S(0.931)PAR;TLEPVKPPTVPNDY(0.003)MT(0.041)S(0.955)PAR ; 114.66 6.79E-05 187624000 4186.1 3567.8 2806.8 3456 3743.9 4496 3627.4 1467.96 3661.2 3385.5 TRUE FALSE FALSE 3854.765768 3876.184734 2910.822477 3441.699988 3699.256438 3563.47892 3729.175081 1915.534246 3259.57552 3503.145873 1.10037261 1.106486819 0.83091672 0.982459798 1.055981273 1.017222533 1.06452178 0.54680402 0.930470965 1 11.77443535 -4.259171702 24.97273306 1.032875685 0.546803849 0.738436964 0.081640388 72.18334848 794863.3873 0.010988314 0.098086797 5.51E-05 4.259171702 -0.486071836 TLEPVRPPVVPNDYVPS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 3 TLEPVRPPVVPNDYVPSPTR 20 1 H7C3Q7;H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9 H7C3Q7 ABI2 Abl interactor 2 1 0 TLEPVRPPVVPNDYVPS(0.734)PT(0.266)R;T(0.001)LEPVRPPVVPNDY(0.028)VPS(0.485)PT(0.485)R;TLEPVRPPVVPNDYVPS(0.5)PT(0.5)R ;; 93.229 0.00041557 109625000 3318.52 2642.1 2586.38 2740.88 2863.62 4075.55 3173.47 1466.79 3474.96 2681.61 TRUE FALSE FALSE 3055.85564 2870.471351 2682.233518 2729.538965 2829.473202 3230.234989 3262.509027 1914.007519 3093.765582 2774.795748 1.1012903 1.034480233 0.966641786 0.983690049 1.019705037 1.16413433 1.17576547 0.68978321 1.114952545 1 11.43816586 -6.993982656 24.22948497 1.048886993 1.014315696 0.043921057 0.129063343 508.8518419 2048920.417 0.020115837 0.026395907 1.01E-07 6.993982656 -0.034571297 TLEPVRPPVVPNDYVPSPT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 TLEPVRPPVVPNDYVPSPTR 20 1 H7C3Q7;H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9 H7C3Q7 ABI2 Abl interactor 2 1 0 TLEPVRPPVVPNDYVPS(0.085)PT(0.915)R 88.418 0.0011779 33603000 744.85 555.01 552.59 627.14 729.44 975.8 678.16 391.43 921.34 790.65 TRUE FALSE FALSE 685.8943365 602.9825913 573.0694715 624.5450609 720.7419044 773.4080805 697.1873444 510.7752051 820.2713071 818.1250286 0.838373491 0.73702988 0.700466862 0.763385838 0.88096792 0.945342158 0.852177015 0.62432414 1.002623411 1 9.676177527 -8.612485696 0.809221183 0.989599676 0.796780527 0.464788237 0.088737233 0.440752117 0.58443318 0.044007172 0.020225681 2.44E-09 8.612485696 -0.192819149 TLETVPLER ddPTM_HeLa_Curcumin_4h_R1 2 TLETVPLER 9 0 P22626;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 ; ; 123.21 0.0011082 15555100 6466.5 5339.7 5347.3 5361.6 5753 7196.1 5625.9 5750.1 6669.4 5644.6 FALSE FALSE TRUE 5954.669702 5801.239875 5545.475642 5339.41512 5684.399232 5703.547743 5783.747613 7503.27902 5937.783506 5840.74943 1.019504393 0.993235533 0.949445907 0.914166099 0.973231141 0.976509575 0.990240667 1.284643197 1.016613292 1 12.51193778 -4.261172059 24.77218936 0.992469232 1.284643289 0.89104525 0.031596367 5.268591876 487929.5746 0.005138997 0.040148499 5.48E-05 4.261172059 0.292174057 TLEVVS(ph)PSQSVTGSAGHTPYYQS(ph)PTDEK ddPTM_HeLa_Curcumin_4h_R1 1 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 T(0.007)LEVVS(0.33)PS(0.199)QS(0.256)VT(0.179)GS(0.204)AGHT(0.151)PY(0.128)Y(0.128)QS(0.317)PT(0.101)DEK 63.534 0.0029833 10709000 1129.9 1153 1448.4 954.79 1915.5 2906.2 959.63 905.8 1473.4 1079.2 TRUE FALSE FALSE 1040.467223 1252.660182 1502.078978 950.839332 1892.658914 2303.42136 986.5546351 1181.97425 1311.771706 1116.70212 0.93173211 1.121749624 1.345102648 0.851470876 1.69486462 2.062699909 0.883453714 1.058450798 1.174683636 1 10.12502868 -6.603091885 1.152878148 0.968035506 1.372878053 0.110089773 0.34905195 0.557876683 1.484999259 0.063747964 0.105596338 2.49E-07 6.603091885 0.404842547 TLEVVS(ph)PSQSVTGSAGHTPYYQSPTDEK ddPTM_HeLa_Curcumin_4h_R1 1 TLEVVSPSQSVTGSAGHTPYYQSPTDEK 28 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(0.014)LEVVS(0.442)PS(0.442)QS(0.099)VTGS(0.003)AGHTPYYQSPTDEK 123.45 1.08E-10 27955000 2172 2264.6 1457 1517.8 4216.7 6229.5 2836.9 4366.3 2972.9 1659.8 TRUE FALSE FALSE 2000.083908 2460.341933 1510.997702 1511.519746 4166.418607 4937.431479 2916.495779 5697.56477 2646.780308 1717.477926 1.164547082 1.432531909 0.879777072 0.880081032 2.42589354 2.874815101 1.698127082 3.317402036 1.541085488 1 10.74607584 -5.735001654 7.907791752 1.080114867 2.542392829 0.722938717 0.432038844 0.066986753 15.86933479 0.05289662 0.104598759 1.84E-06 5.735001654 1.462277962 TLFLGIPDENFEDHSAPPS(ph)PEEK ddPTM_HeLa_Curcumin_4h_R1 2 TLFLGIPDENFEDHSAPPSPEEK 23 0 Q99683-2;Q99683 Q99683-2 MAP3K5 Mitogen-activated protein kinase kinase kinase 5 1 0 TLFLGIPDENFEDHS(0.149)APPS(0.851)PEEK;TLFLGIPDENFEDHS(0.106)APPS(0.893)PEEK ; 80.439 0.0002538 8132500 4285 3828.4 3954.3 3412.9 3988.7 4675.1 3834.5 2629.9 3928.3 4372.1 TRUE FALSE FALSE 3945.837728 4159.309837 4100.849837 3398.778324 3941.137358 3705.431561 3942.08575 3431.744403 3497.375318 4524.03015 0.872195277 0.919381547 0.90645944 0.751272253 0.871156298 0.819055452 0.871365933 0.758559136 0.773066315 1 12.14339283 -13.52287875 0.107321905 1.53787664 0.74067321 0 0.084288954 46.06186622 0.364749122 5.433850141 0.300403874 3.00E-14 13.52287875 -0.797203429 TLFPLIEAK ddPTM_HeLa_Curcumin_4h_R1 2 TLFPLIEAK 9 0 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 0 ; ; 118.5 0.0014674 2862500 1999.92 1355.16 2011.29 1602.7 1650.03 2363.16 2349.01 1560.17 1563.79 1493.96 FALSE FALSE TRUE 1841.624222 1472.293992 2085.830177 1596.068452 1630.35447 1873.013978 2414.916899 2035.858651 1392.246149 1545.874999 1.191315095 0.95240171 1.349287736 1.032469283 1.05464832 1.21162059 1.562168287 1.316962013 0.900620135 1 10.59420795 -4.944403071 5.051024539 1.096092275 1.436260438 0.543087847 0.133337289 0.102483426 5.476716937 0.016597341 0.051543822 1.14E-05 4.944403071 0.340168164 TLFPLIEAK(ac)KK ddPTM_HeLa_Curcumin_4h_R1 1 TLFPLIEAKKK 11 2 P13010 P13010 XRCC5 X-ray repair cross-complementing protein 5 0 1 TLFPLIEAK(0.939)K(0.061)K 84.188 0.007851 1049800 520.15 228.37 548.18 515.05 629.99 543.62 519.86 401.79 506.22 522.72 FALSE TRUE FALSE 478.9795786 248.1092852 568.496033 512.9188596 622.4777807 430.8670841 534.4458725 524.2939214 450.6889325 540.8844811 0.885548755 0.458710305 1.051048889 0.948296499 1.150851619 0.796597239 0.988096148 0.969326981 0.83324434 1 9.079176694 TLGLYGK ddPTM_HeLa_Curcumin_4h_R1 1 TLGLYGK 7 0 P09211;A8MX94 P09211 GSTP1 Glutathione S-transferase P 0 0 107.66 0.015435 14793000 4754.1 4165.2 4126.8 4379.1 4371.5 5388 4628.6 4688.5 4655.1 3391.8 FALSE FALSE TRUE 4377.807968 4525.221328 4279.742838 4360.980445 4319.372718 4270.468065 4758.466059 6118.002067 4144.447176 3509.664798 1.247357859 1.289359979 1.219416407 1.242563235 1.23070805 1.216773769 1.355817815 1.743187005 1.180866953 1 11.77711753 -1 0.528752812 1.136279668 22.76654097 0.771822817 0.08553299 46.26671993 0.411092437 0.021842716 1132.422397 0.1 1 21.6302613 TLGLYGKDQQEAALVDMVNDGVEDLR ddPTM_HeLa_Curcumin_4h_R1 1 TLGLYGKDQQEAALVDMVNDGVEDLR 26 1 P09211;A8MX94 P09211 GSTP1 Glutathione S-transferase P 0 0 67.552 0.0041043 38056000 1495.8 1266.1 889.83 1099.8 537.45 1877.7 1223 1394.3 2421.4 1773.9 FALSE FALSE TRUE 1377.405852 1375.536042 922.8078826 1095.249319 531.0412598 1488.243854 1257.314088 1819.415651 2155.778478 1835.542893 0.75040788 0.749389212 0.50274384 0.596689581 0.289310188 0.810792197 0.684982134 0.991213912 1.174463689 1 10.84199111 -8.337756939 0.71922253 0.979015826 0.646269864 0.415496957 0.188111486 0.515053156 0.569659858 0.079479989 0.042757977 4.59E-09 8.337756939 -0.332745962 MDS(ph)FDEDLAR ddPTM_HeLa_Curcumin_4h_R1 2 MDSFDEDLAR 10 0 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 MDS(1)FDEDLAR;MDS(1)FDEDLAR ; 156.01 0.00063761 10566900 9473.8 8246.4 8937.4 9980 10071.6 11980.3 12006.9 15677.8 9380.3 8122.6 TRUE FALSE FALSE 8723.938733 8959.182071 9268.627906 9938.705404 9951.502748 9495.450734 12343.7813 20457.88905 8351.304558 8404.859745 1.03796363 1.065952597 1.102770086 1.182495093 1.184017705 1.129757191 1.4686481 2.434054781 0.993628069 1 13.03700803 -1.555526728 0.87828775 1.039317437 199.9999714 0.975897231 0.064028655 27.87754608 0.194888195 0.011244749 10933.49679 0.027827441 1.555526728 198.960654 up TLHCEGTEINS(ph)DDEQESK ddPTM_HeLa_Curcumin_4h_R1 5 TLHCEGTEINSDDEQESK 18 0 Q9BPX3;H0Y9Z8 Q9BPX3 NCAPG Condensin complex subunit 3 1 0 TLHCEGTEINS(1)DDEQESK;TLHCEGTEINS(1)DDEQESK;TLHCEGTEINS(0.999)DDEQES(0.001)K;TLHCEGTEINS(1)DDEQESK;TLHCEGTEINS(1)DDEQESK ;;;; 245.12 1.71E-32 502742800 14084.18 13189.48 12904.63 12815.8 15461.8 14248.5 11082.2 9089.5 12356.37 11850.1 TRUE FALSE FALSE 12969.40229 14329.51988 13382.88694 12762.77162 15277.42813 11293.20049 11393.13671 11860.84671 11000.90713 12261.89009 1.057700093 1.168622437 1.091421211 1.040848639 1.245927668 0.920999976 0.929150124 0.96729351 0.897162431 1 13.58189376 TLHCEGTEINS(ph)DDEQESKEVEETATAK ddPTM_HeLa_Curcumin_4h_R1 5 TLHCEGTEINSDDEQESKEVEETATAK 27 1 Q9BPX3;H0Y9Z8 Q9BPX3 NCAPG Condensin complex subunit 3 1 0 TLHCEGT(0.072)EINS(0.926)DDEQES(0.002)KEVEETATAK;T(0.003)LHCEGT(0.157)EINS(0.835)DDEQES(0.005)KEVEET(0.001)ATAK;TLHCEGTEINS(1)DDEQESKEVEETATAK;TLHCEGT(0.068)EINS(0.908)DDEQES(0.024)KEVEETATAK;TLHCEGTEINS(1)DDEQESKEVEETATAK ;;;; 132.86 6.98E-09 981086900 13008.7 9968.64 10989.95 10966.8 11789.6 13472.7 10458.7 7697.33 12222.7 10717.9 TRUE FALSE FALSE 11979.04767 10830.28482 11397.24721 10921.42229 11649.01672 10678.31015 10752.14297 10044.21048 10881.90039 11090.34623 1.080132885 0.97655065 1.027672805 0.98476838 1.050374486 0.962847321 0.969504716 0.905671498 0.981204749 1 13.43701678 -3.435106636 0.545855953 1.033224212 0.65660813 0.414500035 0.035638408 4.929571922 0.518835456 0.007151575 1.44985616 0.000367192 3.435106636 -0.376616082 TLHLQTGNLLNWGR ddPTM_HeLa_Curcumin_4h_R1 2 TLHLQTGNLLNWGR 14 0 P48507-2;P48507 P48507-2 GCLM Glutamate--cysteine ligase regulatory subunit 0 0 ; ; 161.87 8.69E-05 2707400 763.778 653.67 658.16 344.67 658.61 3662.85 1970.59 1598.65 815.08 809.48 FALSE FALSE TRUE 703.3241654 710.1703221 682.5519886 343.2438469 650.7565059 2903.133621 2025.879452 2086.071026 725.6677632 837.6093697 0.839680394 0.847853842 0.814881033 0.409789884 0.776921235 3.46597558 2.418644687 2.490505838 0.866355833 1 9.710133771 -5.2734244 24.98097299 0.860290534 2.754402291 0.900660474 0.303448497 152.4918585 317846.3191 0.042731748 0.096234401 5.33E-06 5.2734244 1.894111758 TLHPAVHAGILAR ddPTM_HeLa_Curcumin_4h_R1 1 TLHPAVHAGILAR 13 0 P31939-2;P31939;C9JLK0 P31939-2 ATIC Bifunctional purine biosynthesis protein PURH;Phosphoribosylaminoimidazolecarboxamide formyltransferase;IMP cyclohydrolase 0 0 100.93 0.0012252 7122600 2727.1 1864.6 2280.7 1928.4 2214.6 4109 2619.4 2431.5 3074.1 2311 FALSE FALSE TRUE 2511.247157 2025.767716 2365.224748 1920.420792 2188.192341 3256.747082 2692.893314 3172.853157 2736.878921 2391.307078 1.050156703 0.847138259 0.989092856 0.803084141 0.915061207 1.361910861 1.126117737 1.326827987 1.144511697 1 11.22358369 -5.265955695 24.98673868 0.984716639 1.257068753 0.619268781 0.109474227 190.7150651 1055143.736 0.014680725 0.03391135 5.42E-06 5.265955695 0.272352114 TLHPDLGTDK(ac)DKEQWK ddPTM_HeLa_Curcumin_4h_R1 1 TLHPDLGTDKDKEQWK 16 2 P00338;P00338-3;P00338-4;P00338-5;P00338-2 P00338 LDHA L-lactate dehydrogenase A chain 0 1 TLHPDLGTDK(0.979)DK(0.021)EQWK 82.925 0.0042683 18189000 5798.6 8224.4 6189.6 5949.7 12817 14359 11479 9693.2 14670 6282 FALSE TRUE FALSE 5339.634691 8935.280489 6418.992021 5925.081718 12664.16565 11380.78154 11801.06985 12648.61206 13060.7377 6500.299032 0.82144447 1.374595298 0.987491804 0.9115091 1.948243547 1.750808922 1.815465687 1.945850798 2.009251826 1 12.66629037 -5.763329637 24.99999873 0.957684878 1.853384483 0.376661719 0.365032619 11.88449917 157184.1793 0.023843229 0.044861334 1.72E-06 5.763329637 0.895699605 TLHPDLGTDKDK(ac)EQWK ddPTM_HeLa_Curcumin_4h_R1 1 TLHPDLGTDKDKEQWK 16 2 P00338;P00338-3;P00338-4;P00338-5;P00338-2 P00338 LDHA L-lactate dehydrogenase A chain 0 1 TLHPDLGTDK(0.163)DK(0.837)EQWK 74.133 0.0063876 12931000 2274.6 2812.5 2169.3 2337.2 4733.6 5351.4 3921 3353.9 5197.4 2361.2 FALSE TRUE FALSE 2094.56301 3055.599968 2249.696166 2327.529286 4677.154912 4241.459317 4031.012707 4376.488671 4627.258223 2443.251524 0.857285052 1.250628491 0.920779602 0.95263597 1.914315765 1.735989633 1.649855804 1.791255885 1.893893517 1 11.25458668 -5.767898936 24.99961248 0.957805595 1.76143551 0.419145775 0.318221242 29.94412101 115889.4475 0.017980546 0.033162678 1.71E-06 5.767898936 0.803629914 TLHS(ph)DDEGTVLDDSR ddPTM_HeLa_Curcumin_4h_R1 1 TLHSDDEGTVLDDSR 15 0 E9PMH2;O00170 E9PMH2 AIP AH receptor-interacting protein 1 0 T(0.004)LHS(0.996)DDEGTVLDDSR 108.58 0.0023799 6198300 766.15 715.25 465.64 536.89 752.53 900.28 457.42 596.64 587.57 712.38 TRUE FALSE FALSE 705.5084191 777.0730229 482.897028 534.6684914 743.5565712 713.5517798 470.2539741 778.5527894 523.115041 737.135152 0.957095069 1.054179849 0.655099715 0.725333055 1.008711319 0.968006719 0.637948106 1.056187305 0.709659605 1 9.525785348 -6.800143985 24.99998388 0.984756269 0.840629332 0.025495057 0.161626567 182.4399775 117840.5394 0.021035936 0.027646907 1.58E-07 6.800143985 -0.144126937 TLHS(ph)PPLQLQQR ddPTM_HeLa_Curcumin_4h_R1 1 TLHSPPLQLQQR 12 0 F8W9A8;B7WPL9;Q6PFW1-7;Q6PFW1-4;Q6PFW1-3;Q6PFW1-2;Q6PFW1;A0A2R8YGT1 F8W9A8 PPIP5K1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 1 0 T(0.049)LHS(0.951)PPLQLQQR 85.163 0.0093316 7466800 2147.2 2217.5 2067.7 1892.6 2139.1 2469.5 1394.6 1764.3 2416.7 2150.4 TRUE FALSE FALSE 1977.246854 2409.170819 2144.330781 1884.768923 2113.59263 1957.297863 1433.728723 2302.226948 2151.594056 2225.12624 0.888599855 1.082711972 0.963689494 0.847039098 0.949875379 0.879634525 0.644335902 1.034650038 0.966953703 1 11.11967147 -5.627326792 1.293962383 0.956904847 0.836846746 0.170926319 0.10564739 0.587500377 1.926102061 0.016220855 0.048005612 2.36E-06 5.627326792 -0.120058101 TLIPS(ph)PPPRPK ddPTM_HeLa_Curcumin_4h_R1 1 TLIPSPPPRPK 11 1 J3KSG3;J3KSS7;Q9NZ52-3;Q9NZ52-4;Q9NZ52-2;Q9NZ52 J3KSG3 GGA3 ADP-ribosylation factor-binding protein GGA3 1 0 TLIPS(1)PPPRPK 68.171 0.01852 124560000 4290 3459.1 3626.3 3522.8 3706.6 3939 3076.2 3652.5 4587.7 3825.4 TRUE FALSE FALSE 3950.441973 3758.089191 3760.693868 3508.223587 3662.401216 3122.006998 3162.509893 4766.130436 4084.440788 3958.332365 0.998006637 0.949412238 0.950070262 0.886288281 0.925238428 0.78871775 0.798950063 1.204075352 1.031858978 1 11.95067704 -6.878088849 1.490740206 0.999659535 0.907716192 0.099794934 0.107951503 0.581177522 2.586001015 0.018270558 0.025489443 1.32E-07 6.878088849 -0.091943343 TLK(ac)MIQPSASGSLVGR ddPTM_HeLa_Curcumin_4h_R1 2 TLKMIQPSASGSLVGR 16 1 H7C608;E2QRF9;O75496;C9K0U5 H7C608 GMNN Geminin 0 1 ; TLK(1)MIQPSASGSLVGR;TLK(1)MIQPSASGSLVGR 146.27 0.0031652 3669900 1936.3 1900.59 1849.35 1358.76 1739.49 2324.1 1947.59 1464.27 1586.8 1450.08 FALSE TRUE FALSE 1783.039812 2064.868531 1917.888538 1353.137811 1718.747718 1842.055462 2002.234134 1910.719182 1412.73201 1500.470172 1.188320731 1.37614767 1.278191712 0.901809204 1.145472766 1.227652169 1.334404489 1.273413639 0.94152622 1 10.55119892 -8.845648276 0.799042869 1.00381155 1.213077 0.36527314 0.125742941 0.646883718 0.790948452 0.07586916 0.027595186 1.43E-09 8.845648276 0.20926545 TLLAK(ac)NLPYK ddPTM_HeLa_Curcumin_4h_R1 1 TLLAKNLPYK 10 1 P19338 P19338 NCL Nucleolin 0 1 TLLAK(1)NLPYK 104.42 0.0069163 1604300 2307.6 1514.4 2135.8 1693.7 1946.1 3262.9 2577.4 2186.1 1976.6 2354.8 FALSE TRUE FALSE 2124.951025 1645.297988 2214.954627 1686.691918 1922.894029 2586.13776 2649.714907 2852.631826 1759.771925 2436.629125 0.87208636 0.675235296 0.909024112 0.692223491 0.789161555 1.061358798 1.087451053 1.170728773 0.722215748 1 11.25067096 -5.08970753 4.871878999 0.888139683 1.118098422 0.511044987 0.11760553 0.170716177 6.756615408 0.01782074 0.047822527 8.13E-06 5.08970753 0.229958738 TLLEQLDDDQ ddPTM_HeLa_Curcumin_4h_R1 3 TLLEQLDDDQ 10 0 O75400-2;O75400-3;O75400 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 0 0 ;; ;; 186.3 0.0015522 45248500 24444.9 19990.7 20675.8 21960.8 21030 25593.4 20422.8 20484.6 23479.1 21159.9 FALSE FALSE TRUE 22510.06037 21718.60703 21442.06334 21869.93203 20779.23099 20285.04034 20995.8088 26730.26024 20903.50147 21895.20495 1.028081739 0.991934402 0.979304071 0.998845733 0.949031125 0.9264604 0.958922689 1.220827131 0.954706819 1 14.41832733 -4.255637353 24.97629954 0.996075704 1.220827229 0.813920523 0.033907396 234.7204575 1010384.528 0.005275609 0.062888541 5.55E-05 4.255637353 0.224751525 TLLIK(ac)TVETR ddPTM_HeLa_Curcumin_4h_R1 2 TLLIKTVETR 10 1 P08670 P08670 VIM Vimentin 0 1 ; TLLIK(1)TVETR;TLLIK(1)TVETR 133.91 0.00090459 6027200 2054.7 2120.45 1807.24 2344.6 1912.91 2672.9 2001.62 2445.8 2435.2 1980.83 FALSE TRUE FALSE 1892.068327 2303.732249 1874.217904 2334.898666 1890.099798 2118.51041 2057.78007 3191.513161 2168.064653 2049.663695 0.923111597 1.123956215 0.914402645 1.13916184 0.922151181 1.033589274 1.003959857 1.557091131 1.057766041 1 11.0011715 -4.259896886 5.322447691 0.985218059 1.580831733 0.803176182 0.079767123 0.043272158 4.340371899 0.010025138 0.093654068 5.50E-05 4.259896886 0.595613674 TLLISS(ph)LSPALPAEHLEDR ddPTM_HeLa_Curcumin_4h_R1 1 TLLISSLSPALPAEHLEDR 19 0 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 0 T(0.004)LLIS(0.156)S(0.457)LS(0.383)PALPAEHLEDR 80.702 0.0020452 14053000 1186 1089.5 1131.6 1075.1 1271.4 2023.5 2235.3 1085.7 1535.8 1020.3 TRUE FALSE FALSE 1092.126849 1183.671525 1173.538091 1070.651521 1256.239385 1603.80329 2298.016502 1416.724932 1367.326582 1055.755349 1.034450689 1.121160813 1.111562534 1.014109492 1.189896302 1.519105058 2.176656272 1.341906469 1.295116888 1 10.04405984 -5.224018448 2.675686568 1.035849759 1.771994896 0.601869061 0.212699349 0.096987401 1.361951484 0.024811143 0.071192933 5.97E-06 5.224018448 0.736145137 TLLISSLS(ph)PALPAEHLEDR ddPTM_HeLa_Curcumin_4h_R1 1 TLLISSLSPALPAEHLEDR 19 0 Q8NDT2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 0 TLLIS(0.004)S(0.017)LS(0.978)PALPAEHLEDR 101.16 0.00042976 3328400 1440.8 1445.1 1292.1 1493.3 1383.6 2900.9 2737.2 1293.2 1799.8 1500.2 TRUE FALSE FALSE 1326.75916 1570.008005 1339.986363 1487.12112 1367.101474 2299.22064 2813.998465 1687.490727 1602.366443 1552.331838 0.854687849 1.011386848 0.863208709 0.957991767 0.880676051 1.481139911 1.81275575 1.087068296 1.0322319 1 10.60022128 -5.257395506 24.2866799 0.929937663 1.495564833 0.647803776 0.174075681 89.07763767 534977.2461 0.021949564 0.053752136 5.53E-06 5.257395506 0.56562717 QQSSSSRES(ph)PVPK ddPTM_HeLa_Curcumin_4h_R1 1 QQSSSSRESPVPK 13 1 Q9UJF2-2;Q9UJF2;H0Y638 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 0 QQS(0.002)S(0.002)S(0.002)S(0.002)RES(0.992)PVPK 70.281 0.015436 127100000 4231.9 4092.8 3660.4 3943.3 4267.9 4521.8 3333.6 1350.3 4618.2 4305.2 TRUE FALSE FALSE 3896.94065 4446.563395 3796.057644 3926.983669 4217.00808 3583.927709 3427.131844 1762.000254 4111.595014 4454.80538 0.874772368 0.998149866 0.852126484 0.881516326 0.946620047 0.804508256 0.769311239 0.395527998 0.922957271 1 12.12114669 -4.074668605 1.114908544 0.933570424 1.46E-13 0.89601297 0.053528683 0.583146067 0.443752158 0.009188682 0.701830836 8.42E-05 4.074668605 -0.933570424 down TLLLSS(ph)DDEF ddPTM_HeLa_Curcumin_4h_R1 1 TLLLSSDDEF 10 0 A0A0J9YYJ3;Q9Y519 A0A0J9YYJ3 TMEM184B Transmembrane protein 184B 1 0 TLLLS(0.279)S(0.721)DDEF 106.18 0.0092521 909400 870.61 809.95 648.17 765.28 714.77 806.72 582.42 678.22 880.74 962.28 TRUE FALSE FALSE 801.7002998 879.9584689 672.1917504 762.1134741 706.2468346 639.3971784 598.7611377 885.0061559 784.1250255 995.7191584 0.805147007 0.883741627 0.675081668 0.765389987 0.709283163 0.642146104 0.601335359 0.888811015 0.787496172 1 9.959595079 -8.370634409 0.341253754 1.0458207 0.685648434 0.197490379 0.105489284 0.833019834 0.215572311 0.119931431 0.047475066 4.26E-09 8.370634409 -0.360172265 TLLSDPTYR ddPTM_HeLa_Curcumin_4h_R1 2 TLLSDPTYR 9 0 P31948;P31948-2;P31948-3;F5H783 P31948 STIP1 Stress-induced-phosphoprotein 1 0 0 ; ; 130.22 0.00060999 12662900 17759.1 15166.3 16499.8 15698.5 16306.3 19999.5 15884 15692 16968.9 15559.9 FALSE FALSE TRUE 16353.4485 16477.20739 17111.2971 15633.54377 16111.85802 15851.37826 16329.66229 20476.41856 15107.45412 16100.60537 1.015703952 1.023390551 1.062773524 0.970991053 1.000698896 0.984520637 1.014226603 1.27177942 0.938315907 1 13.97482731 -4.261791096 6.412060453 1.008054976 1.277300684 0.86529895 0.031935118 0.022379165 5.317097198 0.00312906 0.026092271 5.47E-05 4.261791096 0.269245708 TGGSGS(ph)PPLR ddPTM_HeLa_Curcumin_4h_R1 1 TGGSGSPPLR 10 0 Q8N2Y8 Q8N2Y8 RUSC2 Iporin 1 0 T(0.007)GGS(0.035)GS(0.958)PPLR 89.9 0.019681 45818000 4074.1 3026.3 3402.5 2995.5 3327.7 3647.5 2484.2 1135.6 3774.3 3294.9 TRUE FALSE FALSE 3751.630686 3287.879887 3528.599643 2983.105415 3288.019351 2890.967384 2553.899966 1481.839212 3360.268733 3409.39753 1.100379364 0.964358031 1.034962809 0.874965559 0.964398936 0.847940834 0.749076617 0.434633744 0.985590182 1 11.73530111 -4.074108249 0.668674797 1.038232048 4.73E-15 0.899401708 0.057308337 0.794588091 0.207461194 0.010397317 0.662416634 8.43E-05 4.074108249 -1.038232048 down KLANDFPLDLS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 2 KLANDFPLDLSPVK 14 1 Q96JM2;Q96JM2-3 Q96JM2 ZNF462 Zinc finger protein 462 1 0 KLANDFPLDLS(1)PVK;KLANDFPLDLS(1)PVK ; 142.88 2.27E-05 27452000 6251.4 4081 5651 5921 5579.5 5813.3 5146.8 1717.28 6134 5048.7 TRUE FALSE FALSE 5756.595094 4433.743455 5860.431031 5896.500471 5512.968107 4607.556051 5291.205356 2240.870767 5461.115547 5224.141949 1.101921646 0.848702715 1.121797816 1.128702192 1.055286813 0.881973747 1.01283721 0.428945229 1.045361248 1 12.35097838 -4.071193223 2.034044176 1.038708387 4.67E-16 0.78540406 0.092180844 0.487350621 1.365030444 0.012884168 1.115461441 8.49E-05 4.071193223 -1.038708387 down SPGSTPT(ph)TPTSSQAPQK ddPTM_HeLa_Curcumin_4h_R1 3 SPGSTPTTPTSSQAPQK 17 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 0 S(0.005)PGS(0.007)T(0.045)PT(0.569)T(0.358)PT(0.006)S(0.006)S(0.004)QAPQK;SPGS(0.001)T(0.009)PT(0.79)T(0.197)PT(0.002)S(0.001)SQAPQK;SPGS(0.005)T(0.013)PT(0.9)T(0.082)PTSSQAPQK ;; 229.92 1.07E-21 18162800 5154.6 4374.38 4277.49 4468.54 5337.2 5948.3 5370.2 6662.3 4352.7 3893.34 TRUE FALSE FALSE 4746.607971 4752.481915 4436.017542 4450.050365 5273.557376 4714.555529 5520.873359 8693.604601 3875.2197 4028.633275 1.178217933 1.179675982 1.101122202 1.104605473 1.309018969 1.170261775 1.370408519 2.157953829 0.961919201 1 11.97607477 -1.539808812 0.923619846 1.102665682 200 0.924554098 0.088898691 62.11587211 0.362007375 0.014427237 25752.40733 0.028853014 1.539808812 198.8973343 up TLLTGDGGGEATGS(ph)PLAQGK ddPTM_HeLa_Curcumin_4h_R1 1 TLLTGDGGGEATGSPLAQGK 20 0 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;J3KSW8;Q6WCQ1-3;H0Y2S9;H0Y7E2 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 TLLTGDGGGEAT(0.02)GS(0.98)PLAQGK 306.75 5.87E-99 45250000 2893.6 1930.8 2429 2631.9 2780.1 3681.6 3730.7 4969.5 2163.6 2086.5 TRUE FALSE FALSE 2664.568507 2097.689749 2519.020877 2621.009895 2746.949123 2917.99466 3835.373401 6484.677673 1926.258493 2159.00572 1.234164635 0.971599903 1.166750442 1.213989324 1.272321374 1.35154559 1.776453562 3.003548168 0.892197031 1 11.07615135 TLMGMNWVAT(ph)YCPHIPYVMK ddPTM_HeLa_Curcumin_4h_R1 1 TLMGMNWVATYCPHIPYVMK 20 0 O43825 O43825 B3GALT2 "Beta-1,3-galactosyltransferase 2" 1 0 T(0.115)LMGMNWVAT(0.77)Y(0.115)CPHIPYVMK 47.09 0.01184 39027000 2085.1 4255.8 1884.8 2675.7 1469.1 2035.4 2085.3 1341.4 2477.3 3079.4 TRUE FALSE FALSE 1920.062135 4623.652389 1954.652346 2664.628662 1451.581942 1613.235096 2143.807906 1750.386685 2205.546388 3186.408921 0.602578697 1.451054307 0.613434244 0.836248181 0.455554192 0.506286273 0.672797484 0.549328956 0.692173052 1 11.63771571 -5.775354413 23.69984853 0.846106634 0.552213213 0.305437852 0.235134229 133.4947124 227366.2825 0.036249772 0.065989387 1.68E-06 5.775354413 -0.29389342 KPLSLAGDEETECQS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 2 KPLSLAGDEETECQSSPK 18 1 F5H1K3;Q86TN4-2;Q86TN4;Q86TN4-4 F5H1K3 TRPT1 tRNA 2-phosphotransferase 1 1 0 KPLSLAGDEETECQS(0.625)S(0.375)PK;KPLSLAGDEETECQS(0.842)S(0.158)PK ; 130.89 0.00010945 76156000 9926.4 8238.4 9643.8 9786 9179.6 10558.1 8363.2 3011.2 9718.2 9217.6 TRUE FALSE FALSE 9140.714966 8950.490586 10001.20771 9745.508125 9070.139265 8368.231046 8597.848884 3929.301018 8652.137774 9537.910914 0.958356085 0.938412056 1.048574242 1.02176548 0.950956593 0.877365193 0.90143942 0.41196663 0.907131326 1 13.21945759 -4.071032707 1.692864353 0.979446181 1.37E-15 0.913654823 0.050306398 0.292435631 0.546381946 0.006496919 0.538251615 8.49E-05 4.071032707 -0.979446181 down GLLSDSMT(ph)DVPVDTGVAAR ddPTM_HeLa_Curcumin_4h_R1 1 GLLSDSMTDVPVDTGVAAR 19 0 O43399;O43399-5;O43399-7;A0A087WYR3;O43399-2;O43399-4;O43399-3;A0A087WZ51 O43399 TPD52L2 Tumor protein D54 1 0 GLLS(0.002)DS(0.383)MT(0.616)DVPVDTGVAAR 183.75 4.80E-06 63727000 3599.9 2637.3 3028.1 3109.8 2788.8 3136.7 2205.1 1073.6 2919.4 2954.3 TRUE FALSE FALSE 3314.964116 2865.25646 3140.32405 3096.932472 2755.545381 2486.113062 2266.969171 1400.935698 2599.149124 3056.961705 1.084398313 0.937288961 1.027269673 1.013075325 0.901400033 0.813262743 0.741575914 0.45827715 0.850239347 1 11.57788276 -4.068353213 0.654973164 1.035170278 3.54E-21 0.827167629 0.072197937 0.643363171 0.160262724 0.008232419 0.525350131 8.54E-05 4.068353213 -1.035170278 down TLNDELEIIEGMK ddPTM_HeLa_Curcumin_4h_R1 1 TLNDELEIIEGMK 13 0 P10809;E7EXB4;E7ESH4 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 99.732 0.0043031 0 1258.8 1074.8 1120.5 1434.6 1401.9 1822.7 1294.1 1257.9 1100.3 950.73 FALSE FALSE TRUE 1159.164652 1167.700923 1162.026716 1428.664005 1385.183258 1444.651474 1330.408963 1641.427919 979.5998428 983.7677967 1.178290909 1.186968029 1.181200197 1.452237012 1.408038831 1.468488274 1.352360758 1.668511538 0.995763275 1 9.94217402 -1.000013492 0.121491737 0.851871595 3.240234797 0.860212378 0.077066147 22.54029836 0.187819004 0.320812352 9.163891546 0.099996893 1.000013492 2.388363203 TLNDELEIIEGMKFDR ddPTM_HeLa_Curcumin_4h_R1 2 TLNDELEIIEGMKFDR 16 1 P10809;E7EXB4;E7ESH4 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 ; ; 207.92 1.22E-10 83415000 4853.6 4541.8 4730.9 4768.1 3652.5 9724.7 5164.7 5026.1 9212.2 5681.2 FALSE FALSE TRUE 4469.432439 4934.372954 4906.231316 4748.370866 3608.946323 7707.6876 5309.607582 6558.534753 8201.644708 5878.621277 0.760285827 0.839375888 0.834588773 0.807735461 0.613910329 1.311138656 0.903206268 1.115658663 1.395164669 1 12.52126212 -5.258594941 24.99998692 0.854878393 1.089321685 0.157566089 0.216192685 214.5256745 1885470.115 0.020486578 0.049798108 5.51E-06 5.258594941 0.234443291 TLNMTTS(ph)PEEK ddPTM_HeLa_Curcumin_4h_R1 1 TLNMTTSPEEK 11 0 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 1 0 T(0.001)LNMT(0.065)T(0.216)S(0.719)PEEK 92.943 0.017954 67679000 8413.8 7203.4 7683.1 7700.2 8292.6 8539.7 7047.8 6415.7 9074.5 7122.5 TRUE FALSE FALSE 7747.838852 7826.029798 7967.842445 7668.338613 8193.716161 6768.469958 7245.5423 8371.817396 8079.050053 7370.006345 1.051266239 1.061875585 1.081117447 1.040479242 1.111765143 0.918380479 0.983112084 1.135930826 1.096206662 1 12.84745015 -4.245058995 24.13712478 1.02877667 1.13593096 0.200585813 0.055688768 2102.182837 3097565.949 0.007231019 0.245889716 5.69E-05 4.245058995 0.10715429 TLPIRS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 TLPIRSPK 8 1 Q5UIP0-2;Q5UIP0;H7C2B5 Q5UIP0-2 RIF1 Telomere-associated protein RIF1 1 0 TLPIRS(1)PK 69.65 0.019391 48809000 1331.4 1587.5 1236 1950.9 2171.6 2663.3 2151.8 554.95 2260 2528.6 TRUE FALSE FALSE 1226.018285 1724.716426 1281.807247 1942.827693 2145.705088 2110.901558 2212.173717 724.1517003 2012.083654 2616.468662 0.468577477 0.659177177 0.489899713 0.742538109 0.820076739 0.806775021 0.845480685 0.276766816 0.769007359 1 11.35340526 -9.505468163 1.260067749 0.999610373 0.635306743 0.18403227 0.185247952 0.394995744 1.124409856 0.12295566 0.029877908 3.12E-10 9.505468163 -0.36430363 TLPS(ph)PIDAK ddPTM_HeLa_Curcumin_4h_R1 1 TLPSPIDAK 9 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 0 T(0.162)LPS(0.838)PIDAK 89.403 0.020212 8401700 2769.2 1995.3 2026.5 2679.6 2251.7 3301.5 2890.3 2211.5 2604.9 2374.6 TRUE FALSE FALSE 2550.014898 2167.764841 2101.603873 2668.512525 2224.849948 2616.731684 2971.394039 2885.77617 2319.148987 2457.117173 1.037807609 0.882239099 0.855312842 1.086033891 0.905471653 1.064960073 1.209300912 1.174456066 0.94384957 1 11.26275094 -4.910717865 4.100249562 0.993711089 1.190472896 0.594118775 0.073096379 0.123662185 3.878109677 0.010389299 0.033961044 1.23E-05 4.910717865 0.196761807 TLPSTSSS(ph)GSK ddPTM_HeLa_Curcumin_4h_R1 1 TLPSTSSSGSK 11 0 A0A286YEX4;P08651-4;P08651-5;P08651-3;P08651-6;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 0 TLPST(0.001)S(0.001)S(0.034)S(0.898)GS(0.065)K 120.53 0.0030598 0 3750.1 3435.4 3111.3 3640.3 3782.2 5101.6 5263.6 1872.7 3832.8 3184.2 TRUE FALSE FALSE 3453.275628 3732.340668 3226.607515 3625.237403 3737.099735 4043.470653 5411.28245 2443.677609 3412.351429 3294.850713 1.048082578 1.132779902 0.979287924 1.100273645 1.134224297 1.227209062 1.64234526 0.741665654 1.035661924 1 11.68599738 -5.63689875 2.095804428 1.031369165 1.241965251 0.093122612 0.206937388 0.399662771 3.543983927 0.027937449 0.065602244 2.31E-06 5.63689875 0.210596086 TLPSTSSSGS(ph)KR ddPTM_HeLa_Curcumin_4h_R1 1 TLPSTSSSGSKR 12 1 A0A286YEX4;P08651-4;P08651-5;P08651-3;P08651-6;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 1 0 TLPSTSS(0.007)S(0.128)GS(0.864)KR 89.992 0.0070976 41472000 2405.6 1826.9 1745.8 2077.9 1761.9 3149.1 2665.6 964.46 2459.8 1895.2 TRUE FALSE FALSE 2215.194222 1984.809095 1810.500884 2069.3022 1740.890493 2495.941162 2740.389562 1258.519414 2189.966094 1961.058059 1.129591351 1.012111338 0.923226559 1.055196806 0.887730215 1.272752304 1.397403585 0.641755306 1.116726802 1 10.93741653 -9.780637199 1.766257547 0.999896593 1.065032979 0 0.201084771 1.858517651 10.49156699 0.137133348 0.028983887 1.66E-10 9.780637199 0.065136386 TLPSTSSSGSK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 TLPSTSSSGSKR 12 1 A0A286YEX4;P08651-4;P08651-5;P08651-3;P08651-6;P08651-2;P08651 A0A286YEX4 NFIC Nuclear factor 1 C-type 0 1 ; TLPSTSSSGSK(1)R;TLPSTSSSGSK(1)R 228.84 9.14E-39 22024000 957.84 803.87 986.31 848.27 839.11 926.96 681.36 667.22 813.38 673.38 FALSE TRUE FALSE 882.0259533 873.3529408 1022.863516 844.7600835 829.1041613 734.698047 700.4771278 870.6523065 724.154249 696.7799049 1.265860205 1.253412928 1.467986532 1.212377219 1.189908256 1.05441911 1.005306156 1.24953705 1.039286931 1 9.444559207 -3.89402909 19.31672727 1.157559041 11.50536475 0.029127298 0.139271596 1313.733315 241022.5023 0.021729212 3879.817764 0.000127635 3.89402909 10.34780571 TLQPPES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 TLQPPESPR 9 0 Q86UU1-3;Q86UU1-2;Q86UU1 Q86UU1-3 PHLDB1 Pleckstrin homology-like domain family B member 1 1 0 TLQPPES(1)PR;TLQPPES(1)PR;TLQPPES(1)PR ;; 141.71 0.0022694 526231800 11124 8526.8 8129.7 8783.3 9182 10584.9 7313.7 3555.2 10471.6 8378.9 TRUE FALSE FALSE 10243.52366 9263.818597 8430.993834 8746.957032 9072.510647 8389.472424 7518.902738 4639.164114 9322.891679 8670.066151 1.181481604 1.068483035 0.972425549 1.008868546 1.046417696 0.967636495 0.867225533 0.535078283 1.075296487 1 13.08182729 -3.967168568 0.946209591 1.073294742 2.37E-13 0.885256745 0.056013705 1.002975102 0.470090055 0.012085054 1.25440542 0.000107853 3.967168568 -1.073294742 TLQQNAESR ddPTM_HeLa_Curcumin_4h_R1 2 TLQQNAESR 9 0 O95816-2;O95816 O95816-2 BAG2 BAG family molecular chaperone regulator 2 0 0 ; ; 123.86 0.0010583 1905020 725.76 591.73 331.197 629.54 539.06 848.23 653.6 513.204 729.16 696.85 FALSE FALSE TRUE 668.3153302 642.8765045 343.4714522 626.9351303 532.6320616 672.2975365 671.9382569 669.6775371 649.1729723 721.0654856 0.926844154 0.89156466 0.476338778 0.869456579 0.738673633 0.932366824 0.931868562 0.928733313 0.900296832 1 9.493986478 -7.19875774 3.634482822 0.966437621 0.814829722 0.149344061 0.131673644 0.278913505 7.337868946 0.022609112 0.027513235 6.33E-08 7.19875774 -0.151607899 TLQRLSS(ph)GFDDIDLPSAVK ddPTM_HeLa_Curcumin_4h_R1 1 TLQRLSSGFDDIDLPSAVK 19 1 Q9Y446;Q9Y446-2;E9PKC4 Q9Y446 PKP3 Plakophilin-3 1 0 T(0.002)LQRLS(0.395)S(0.603)GFDDIDLPSAVK 99.454 0.00046364 77011000 3968.3 3447.5 3462.4 3300.9 3329.8 5999.6 4113.2 399.28 4939.2 3852.9 TRUE FALSE FALSE 3654.204868 3745.486538 3590.71959 3287.24175 3290.09431 4755.215331 4228.605322 521.0186339 4397.382117 3986.787988 0.916578679 0.939474722 0.900654763 0.824533875 0.825249379 1.192743468 1.060654676 0.130686316 1.102988704 1 11.96101117 -4.257047269 24.98016885 0.956850088 0.130685984 0.830997152 0.113818917 125.1939504 712015.1839 0.014795175 0.156150729 5.53E-05 4.257047269 -0.826164104 TLQTDSIDSFETQRT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 TLQTDSIDSFETQRTPR 17 1 A0A3B3IS71;P06400 A0A3B3IS71 RB1 Retinoblastoma-associated protein 1 0 TLQTDSIDSFETQRT(1)PR 203.93 1.20E-09 7152600 2332.5 2306.3 2175 2540 2226.1 3890.7 3128.1 1600.2 2857.7 2368.6 TRUE FALSE FALSE 2147.880164 2505.646295 2255.607413 2529.490153 2199.555211 3083.724963 3215.866067 2088.093614 2544.21746 2450.908674 0.87636075 1.022333603 0.920314754 1.032062182 0.897444787 1.258196601 1.312111749 0.851967124 1.038071099 1 11.25910101 -5.269676929 24.92814038 0.949339806 1.157893819 0.266900272 0.12605842 432.5152103 1308861.055 0.016679583 0.037890305 5.37E-06 5.269676929 0.208554013 TLRDS(ph)PNVEAAHLAR ddPTM_HeLa_Curcumin_4h_R1 1 TLRDSPNVEAAHLAR 15 1 Q9UHF7;Q9UHF7-3;Q9UHF7-2;E5RFF3;H0YC29;E5RJ97 Q9UHF7 TRPS1 Zinc finger transcription factor Trps1 1 0 T(0.018)LRDS(0.982)PNVEAAHLAR 64.331 0.016849 9005900 1133.8 968.93 1140.6 1077.7 1047.2 1250.4 1143.4 674.96 1341.3 768.48 TRUE FALSE FALSE 1044.058534 1052.679992 1182.871639 1073.240763 1034.712824 991.0529451 1175.480727 880.7521969 1194.162746 795.1846228 1.312976262 1.323818346 1.487543402 1.349674946 1.301223382 1.246318046 1.478248815 1.107607179 1.501742754 1 9.635146048 -8.965599039 0.719532989 0.991888465 1.335715486 0 0.185116283 0.371246104 0.3446593 0.071966707 0.020934827 1.08E-09 8.965599039 0.34382702 TLS(ph)DDLDEAAK ddPTM_HeLa_Curcumin_4h_R1 2 TLSDDLDEAAK 11 0 A0A087WV29;Q9H0A0-2;Q9H0A0 A0A087WV29 NAT10 N-acetyltransferase 10 1 0 T(0.018)LS(0.982)DDLDEAAK;T(0.002)LS(0.998)DDLDEAAK ; 168.98 0.00024727 7483200 4917 4338.6 4949.6 5094.2 5183.2 5125.5 3896.2 3165.8 4979.3 3968.4 TRUE FALSE FALSE 4527.814262 4713.609252 5133.03653 5073.12155 5121.393725 4062.413524 4005.516886 4131.037846 4433.083248 4106.301605 1.102650194 1.147896503 1.250038849 1.235447865 1.247203498 0.989312017 0.975456085 1.006023971 1.079580526 1 12.00362388 -2.753746291 10.51642537 1.081984913 0.741612046 0 0.10784044 0 0 0.016194614 0 0.001763006 2.753746291 -0.340372867 TLS(ph)DESIYNSQR ddPTM_HeLa_Curcumin_4h_R1 3 TLSDESIYNSQR 12 0 O43166-3;O43166-2;O43166;F5GYF8 O43166-3 SIPA1L1 Signal-induced proliferation-associated 1-like protein 1 1 0 T(0.01)LS(0.966)DES(0.023)IYNS(0.001)QR;T(0.207)LS(0.696)DES(0.097)IYNSQR;T(0.225)LS(0.775)DESIYNSQR ;; 198.52 1.22E-06 363651000 4627.1 3924.2 3833.86 4454.9 4015 4908.6 4199.1 3558.19 5000.9 4205.3 TRUE FALSE FALSE 4260.860153 4263.390362 3975.946224 4436.466804 3967.123747 3890.501029 4316.915445 4643.065751 4452.313782 4351.433862 0.979185319 0.979766784 0.913709446 1.019541362 0.911681959 0.894073345 0.992067346 1.067019722 1.023183144 1 12.08727515 -7.916072003 0.968114842 0.995562732 0.964447878 0.080653709 0.050693825 1.067636408 2.129524139 0.013712795 0.011347865 1.21E-08 7.916072003 -0.031114854 TLS(ph)DESLCSGR ddPTM_HeLa_Curcumin_4h_R1 4 TLSDESLCSGR 11 0 O60292;M0R2Q7 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 0 T(0.003)LS(0.577)DES(0.42)LCSGR;T(0.225)LS(0.773)DES(0.003)LCSGR;T(0.009)LS(0.942)DES(0.049)LCSGR;T(0.02)LS(0.868)DES(0.11)LCS(0.002)GR ;;; 190.66 3.90E-05 269662000 8504.26 7381.03 7637.45 8076.78 7903.39 8789.96 6402.09 4323.22 8664.34 7424.14 TRUE FALSE FALSE 7831.138847 8019.013344 7920.500616 8043.360424 7809.147236 6966.823213 6581.715415 5641.349876 7713.883579 7682.128312 1.019397038 1.043853086 1.031029461 1.0470224 1.01653434 0.906887119 0.856756767 0.73434726 1.004133655 1 12.90729035 -4.650447126 1.284995374 1.017545501 0.709769093 0.950459994 0.021575064 0.126397283 0.279668304 0.003585413 0.042328784 2.24E-05 4.650447126 -0.307776408 TLS(ph)ESFSR ddPTM_HeLa_Curcumin_4h_R1 1 TLSESFSR 8 0 O94921 O94921 CDK14 Cyclin-dependent kinase 14 1 0 T(0.069)LS(0.816)ES(0.113)FS(0.002)R 92.239 0.019596 10201000 1736 1302.7 1393.1 1702.1 1678.8 2367.4 2138.3 1924.5 1721.6 1656 TRUE FALSE FALSE 1598.593768 1415.299583 1444.729511 1695.057161 1658.781406 1876.374554 2198.294943 2511.271191 1532.744787 1713.545877 0.932915652 0.825947879 0.84312275 0.989210259 0.968040266 1.095024405 1.282892377 1.465540681 0.894487161 1 10.7427691 -4.632952574 1.310417248 0.946261954 1.531146881 0.910810875 0.057339147 0.182586836 0.418632675 0.009835188 0.118571804 2.33E-05 4.632952574 0.584884926 TLS(ph)KSEHSLFQAK ddPTM_HeLa_Curcumin_4h_R1 1 TLSKSEHSLFQAK 13 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 T(0.095)LS(0.904)KS(0.001)EHSLFQAK 102.38 0.0025451 92996000 3692.5 2775.4 2928.1 3189.2 3416.3 4484.7 3313.5 1739.4 4960.6 4163.3 TRUE FALSE FALSE 3400.234729 3015.293209 3036.617962 3176.003935 3375.562854 3554.522667 3406.467892 2269.735053 4416.434591 4307.974365 0.789288524 0.699932951 0.704883016 0.737238355 0.7835615 0.825103022 0.790735414 0.526868282 1.025176618 1 12.07279395 -8.747873118 0.556155931 1.017466336 0.727472593 0.669856757 0.078789315 0.482467924 0.275764694 0.068320917 0.020718566 1.79E-09 8.747873118 -0.289993743 TLS(ph)LSYNALGAPALAR ddPTM_HeLa_Curcumin_4h_R1 1 TLSLSYNALGAPALAR 16 0 Q96HA7-2;Q96HA7 Q96HA7-2 TONSL Tonsoku-like protein 1 0 T(0.289)LS(0.356)LS(0.356)YNALGAPALAR 75.669 0.017426 25631000 2850.1 2433.4 2880.8 2991.2 3310 3019.4 2877.9 2098.8 2494.8 2364.9 TRUE FALSE FALSE 2624.511578 2643.732253 2987.564982 2978.823207 3270.530412 2393.142404 2958.646129 2738.714458 2221.126682 2447.080099 1.072507426 1.08036196 1.220869306 1.217296977 1.336503212 0.977958345 1.209051608 1.119176466 0.90766407 1 11.25684561 -7.16812526 1.579111393 1.028838204 1.179728191 0.414813317 0.096031448 0.291853966 1.389588019 0.016311663 0.020082367 6.79E-08 7.16812526 0.150889987 TLS(ph)MIEEEIR ddPTM_HeLa_Curcumin_4h_R1 7 TLSMIEEEIR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 T(0.21)LS(0.79)MIEEEIR;T(0.002)LS(0.998)MIEEEIR;T(0.117)LS(0.883)MIEEEIR;T(0.02)LS(0.98)MIEEEIR;TLS(1)MIEEEIR;T(0.012)LS(0.988)MIEEEIR;T(0.035)LS(0.965)MIEEEIR ;;;;;; 142.76 0.0013306 259287500 18220.9 15376.35 16351.77 17010.92 16151.75 21469.39 18991.88 13487.06 18938.88 16100.7 TRUE FALSE FALSE 16778.69654 16705.41318 16957.78098 16940.53332 15959.15093 17016.3965 19524.74104 17599.20251 16861.33225 16660.19813 1.007112665 1.002713956 1.017861904 1.016826642 0.957920837 1.021380201 1.171939307 1.056362138 1.012072733 1 14.02411794 -4.891548688 6.858328651 1.00246273 1.113137492 0.677998839 0.030449373 0.073767511 4.194759472 0.00363587 0.01108805 1.28E-05 4.891548688 0.110674762 TLS(ph)NESEESVK ddPTM_HeLa_Curcumin_4h_R1 1 TLSNESEESVK 11 0 Q8NHM5-4;Q8NHM5-2;Q8NHM5-3;Q8NHM5;S4R3G4;F8WBN2;F6SRV7;Q8NHM5-5 Q8NHM5-4 KDM2B Lysine-specific demethylase 2B 1 0 TLS(1)NESEESVK 168.31 0.00025137 13783000 1781.1 1418.5 1657.9 1004.8 1597.2 1682.4 1318.1 1247.2 1464.5 1406.5 TRUE FALSE FALSE 1640.124056 1541.108819 1719.343232 1000.642404 1578.154433 1333.451275 1355.082339 1627.465539 1303.848014 1455.37577 1.126941982 1.058907844 1.181374094 0.687549171 1.084362173 0.916224732 0.931087604 1.118244217 0.895884101 1 10.50717598 TLS(ph)PEFNER ddPTM_HeLa_Curcumin_4h_R1 1 TLSPEFNER 9 0 Q9BSJ8;Q9BSJ8-2 Q9BSJ8 ESYT1 Extended synaptotagmin-1 1 0 T(0.1)LS(0.9)PEFNER 92.611 0.017462 5931600 2034 1806.8 1820.3 2203.9 1634.5 1769.9 1760.7 2187 1961.9 2003.9 TRUE FALSE FALSE 1873.006754 1962.971741 1887.761919 2194.780846 1615.009655 1402.802789 1810.100503 2853.806232 1746.684478 2073.535376 0.903291439 0.946678684 0.910407385 1.058472824 0.778867664 0.676527059 0.87295376 1.376299756 0.842370233 1 11.01787695 -9.404179522 1.028506834 1.001807444 0.925185975 0 0.182282197 2.302795303 4.190169485 0.133377937 0.030843672 3.94E-10 9.404179522 -0.076621469 NMTVEQLLTGS(ph)PTSPTVEPEKPTR ddPTM_HeLa_Curcumin_4h_R1 2 NMTVEQLLTGSPTSPTVEPEKPTR 24 1 Q9C0C9;K7ES11 Q9C0C9 UBE2O E2/E3 hybrid ubiquitin-protein ligase UBE2O 1 0 NMT(0.001)VEQLLT(0.215)GS(0.776)PT(0.006)S(0.002)PTVEPEKPTR;NMTVEQLLT(0.003)GS(0.953)PT(0.041)S(0.002)PTVEPEKPTR ; 135.13 9.15E-07 51955000 3829.3 3160.13 3587.2 3837.4 3510.3 3696.6 2729.42 1230.67 3968.9 3193.1 TRUE FALSE FALSE 3526.206864 3433.277556 3720.144788 3821.521856 3468.441965 2929.883491 2806.000179 1605.895618 3533.5216 3304.059987 1.067234517 1.039108724 1.12593137 1.156613945 1.049751511 0.886752511 0.849258243 0.486037065 1.06944838 1 11.69002416 -4.067457733 1.093623281 1.049544526 0.026195932 0.910658093 0.055611542 0.572623525 0.413901134 0.009542039 0.745107565 8.56E-05 4.067457733 -1.023348594 down TLS(ph)PTPASATAPTSQGIPT(ph)SDEES(ph)TPKK ddPTM_HeLa_Curcumin_4h_R1 1 TLSPTPASATAPTSQGIPTSDEESTPKK 28 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 3 0 T(0.149)LS(0.644)PT(0.09)PAS(0.031)AT(0.039)APT(0.014)S(0.032)QGIPT(0.488)S(0.488)DEES(0.544)T(0.481)PKK 52.577 0.0049183 26714000 2955.8 2165.6 2545.3 2732.9 2486.4 3289 3094.2 848.6 3342.8 2370.4 TRUE FALSE FALSE 2721.845311 2352.784814 2639.631057 2721.591984 2456.751304 2606.824325 3181.014924 1107.334234 2976.103203 2452.771224 1.109702073 0.95923533 1.076183148 1.109598791 1.001622687 1.062807774 1.296906492 0.451462502 1.213363552 1 11.26019696 -4.24725474 24.88426254 1.061719127 0.451462057 0.781369381 0.100517734 732.8163949 1285565.343 0.011861123 0.338199099 5.66E-05 4.24725474 -0.61025707 TLS(ph)PTPASATAPTSQGIPTSDEESTPKK ddPTM_HeLa_Curcumin_4h_R1 1 TLSPTPASATAPTSQGIPTSDEESTPKK 28 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 T(0.038)LS(0.709)PT(0.251)PAS(0.001)ATAPTSQGIPTSDEESTPKK 126.8 1.31E-10 12300000 3139.2 2262.1 2748.2 3301 2706 2368.1 1378.5 941.35 3595.3 2406 TRUE FALSE FALSE 2890.729008 2457.625844 2850.05071 3287.341337 2673.732717 1876.929366 1417.177 1228.363282 3200.904585 2489.608321 1.161117989 0.987153611 1.144778753 1.320425108 1.073957174 0.753905484 0.569236931 0.493396199 1.285706092 1 11.28170307 -5.056825069 2.41295013 1.095574639 0.526604174 0.840038368 0.108445134 0.085620818 0.967991464 0.015203286 0.052407671 8.77E-06 5.056825069 -0.568970465 TLS(ph)PTPSAEGYQDVR ddPTM_HeLa_Curcumin_4h_R1 2 TLSPTPSAEGYQDVR 15 0 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4;A0A494C1P1;A0A494C1G0;H0Y7N6;F6XFR5 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 T(0.138)LS(0.862)PTPSAEGYQDVR;T(0.044)LS(0.953)PT(0.004)PSAEGYQDVR ; 249.36 1.64E-30 1150231000 5882.4 5062.3 4974.9 4795.4 4630.8 4201.9 2610.9 2242.89 5544.5 4342.6 TRUE FALSE FALSE 5416.801833 5499.862655 5159.27417 4775.557905 4575.580734 3330.378575 2684.154827 2926.736836 4936.282222 4493.505027 1.205473634 1.223958274 1.148162546 1.062769014 1.018265409 0.741153855 0.597341009 0.65132604 1.098537154 1 12.1336255 -5.245001298 1.94909626 1.112559203 0.617341564 0.916934633 0.062656458 0.097050595 0.703411765 0.013384453 0.043230205 5.69E-06 5.245001298 -0.495217639 LVPS(ph)QEETK ddPTM_HeLa_Curcumin_4h_R1 1 LVPSQEETK 9 0 P49321-4;P49321;P49321-3 P49321-4 NASP Nuclear autoantigenic sperm protein 1 0 LVPS(1)QEETK 125.72 0.0047538 132330000 5462.7 4735.6 4827.3 4543.4 6296 6305.9 6807.9 9027.1 4221 3980.9 TRUE FALSE FALSE 5030.321531 5144.924163 5006.203985 4524.600615 6220.924312 4997.985258 6998.911351 11779.42123 3757.96686 4119.235979 1.221178286 1.248999618 1.215323427 1.098407724 1.510213142 1.21332822 1.699079972 2.859613116 0.912297057 1 12.00816106 -1.531790035 0.832696741 1.13273409 200 0.925223452 0.145844616 36.94522159 0.285408476 0.02223233 13663.92165 0.029390702 1.531790035 198.8672659 up NEIIQS(ph)PISQVPSVEK ddPTM_HeLa_Curcumin_4h_R1 2 NEIIQSPISQVPSVEK 16 0 Q7Z3T8 Q7Z3T8 ZFYVE16 Zinc finger FYVE domain-containing protein 16 1 0 NEIIQS(0.695)PIS(0.305)QVPSVEK;NEIIQS(0.993)PIS(0.007)QVPSVEK ; 202.6 2.90E-10 20561400 12277.2 10327.2 10656.3 11499 11002.1 16134.5 11687.3 15312 12270.4 9097.8 TRUE FALSE FALSE 11305.44667 11219.83715 11051.23185 11451.42018 10870.90714 12788.02283 12015.21418 19980.55831 10924.36782 9413.947873 1.20092514 1.191831238 1.17392108 1.216431229 1.154766023 1.358412326 1.27632045 2.122441996 1.160444902 1 13.20058415 -1.483989746 0.917077731 1.121640742 200 0.906986309 0.089086951 82.40939778 0.436856593 0.016208746 33966.40775 0.032810304 1.483989746 198.8783593 up TLSASTQDLS(ph)PH ddPTM_HeLa_Curcumin_4h_R1 2 TLSASTQDLSPH 12 0 Q6P597-2;Q6P597;Q6P597-3 Q6P597-2 KLC3 Kinesin light chain 3 1 0 TLSASTQDLS(1)PH;TLSASTQDLS(1)PH ; 151.16 0.00047684 39775000 5085.7 4884.6 4473 5506.3 4931.1 4845.8 4374.9 10162 5349.9 4940.2 TRUE FALSE FALSE 4683.161479 5306.803059 4638.773315 5483.51639 4872.299853 3840.726457 4497.64792 13260.34702 4763.029355 5111.871582 0.916134414 1.038133093 0.907451066 1.072702297 0.953134243 0.751334691 0.879843683 2.594029761 0.931758413 1 12.31963588 -4.259948028 24.99852169 0.950349522 2.594030301 0.971196182 0.085489005 14.95472845 250651.3004 0.012069716 0.102100693 5.50E-05 4.259948028 1.643680779 TLSDDLDEAAKEFQEK ddPTM_HeLa_Curcumin_4h_R1 1 TLSDDLDEAAKEFQEK 16 1 A0A087WV29;Q9H0A0-2;Q9H0A0 A0A087WV29 NAT10 N-acetyltransferase 10 0 0 104.94 0.0017338 1864800 808.69 510.64 570.08 762.09 662.05 846.94 573.57 497.94 828.33 734.61 FALSE FALSE TRUE 744.6813332 554.7774462 591.2076663 758.9366735 654.1554861 671.275097 589.6628305 649.7596138 737.4642714 760.1376428 0.979666433 0.729838144 0.777763964 0.998420063 0.860575045 0.88309677 0.775731653 0.85479205 0.970172019 1 9.57011687 -7.39617165 8.555080912 0.991042002 0.843790097 0.470227664 0.069544367 0.188841911 12.30562931 0.01195946 0.013649973 4.02E-08 7.39617165 -0.147251905 TLSDFNSLISS(ph)PHLGR ddPTM_HeLa_Curcumin_4h_R1 1 TLSDFNSLISSPHLGR 16 0 Q9NRJ4 Q9NRJ4 TULP4 Tubby-related protein 4 1 0 TLSDFNSLIS(0.417)S(0.583)PHLGR 127.49 0.00022913 9333200 1694.9 1535.3 1538.1 1462.4 1940.8 1729.2 1185.6 662.53 2175.5 1551.1 TRUE FALSE FALSE 1560.746877 1668.004491 1595.103339 1456.348976 1917.657228 1370.544428 1218.864745 864.5323471 1936.853093 1605.00061 0.972427591 1.03925474 0.993833479 0.907382195 1.194801557 0.853921438 0.759416998 0.538649233 1.206761593 1 10.64835813 -4.588728586 1.80199814 0.996917517 0.526087875 0.707851471 0.10186974 0.149930753 0.75654805 0.010186833 0.096121813 2.58E-05 4.588728586 -0.470829642 TLSDVEDQKELAS(ph)PVSPELR ddPTM_HeLa_Curcumin_4h_R1 2 TLSDVEDQKELASPVSPELR 20 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 0 TLSDVEDQKELAS(0.994)PVS(0.005)PELR;T(0.009)LS(0.042)DVEDQKELAS(0.751)PVS(0.198)PELR ; 92.136 0.00044324 46104000 3299.4 2690.3 2930.3 3689 3022.7 4079.5 3296.5 4265 3334.7 3387.7 TRUE FALSE FALSE 3038.249008 2922.837544 3038.899496 3673.735895 2986.656277 3233.365715 3388.990918 5565.378866 2968.891753 3505.422323 0.866728379 0.833804682 0.866913945 1.048015205 0.8520104 0.922389777 0.966785342 1.587648607 0.846942673 1 11.77537255 -4.260150833 4.461746507 0.924937808 1.633509295 0.896996029 0.068746591 0.048146434 2.375892773 0.010106365 0.1071807 5.49E-05 4.260150833 0.708571487 TLSDVEDQKELASPVS(ph)PELR ddPTM_HeLa_Curcumin_4h_R1 2 TLSDVEDQKELASPVSPELR 20 1 Q5T4S7-3;Q5T4S7-4;Q5T4S7;Q5T4S7-2;Q5T4S7-5 Q5T4S7-3 UBR4 E3 ubiquitin-protein ligase UBR4 1 0 TLSDVEDQKELAS(0.112)PVS(0.888)PELR;TLSDVEDQKELAS(0.039)PVS(0.961)PELR ; 105.56 0.00014803 76376000 5016.9 4358.4 4294.8 5284 4447.5 4858.8 3487.2 4239.2 4929.7 4993.2 TRUE FALSE FALSE 4619.807071 4735.120675 4453.969066 5262.136208 4394.466467 3851.03011 3585.041447 5531.712565 4388.924244 5166.713328 0.894148132 0.916466693 0.862050743 1.018468778 0.850534215 0.745353935 0.693872723 1.070644376 0.849461537 1 12.33503112 -9.701624681 0.185883193 1.119962896 0.822481714 0 0.114930643 15.08689551 0.700650438 1.118821549 0.203864538 1.99E-10 9.701624681 -0.297481182 TLSES(ph)FSR ddPTM_HeLa_Curcumin_4h_R1 1 TLSESFSR 8 0 O94921 O94921 CDK14 Cyclin-dependent kinase 14 1 0 T(0.001)LS(0.346)ES(0.653)FSR 123.21 0.0072727 23347000 2043.1 2438.4 2098.4 1965.1 1787.4 3389.2 2747.9 2210.7 2397.8 1889.3 TRUE FALSE FALSE 1881.386479 2649.164431 2176.16855 1956.968937 1766.086422 2686.241716 2824.998678 2884.732253 2134.767339 1954.953034 0.962369144 1.355103874 1.113156435 1.001031177 0.903390716 1.374069693 1.445046827 1.475601819 1.091978836 1 10.93291823 -5.15623291 4.893581056 1.017820899 1.447532512 0.653364904 0.121498706 0.096639953 3.610994911 0.01820457 0.0481059 6.98E-06 5.15623291 0.429711613 TLSEVDY(ph)APAGPAR ddPTM_HeLa_Curcumin_4h_R1 2 TLSEVDYAPAGPAR 14 0 O15357;A0A0A0MTP6;H0YFZ4;O15357-2 O15357 INPPL1 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2" 1 0 TLSEVDY(1)APAGPAR;TLSEVDY(1)APAGPAR ; 227.36 1.55E-19 24349000 2603.76 2816.94 2689.24 2610 2360.64 4233.1 2177.55 2033.46 3898.7 2558.36 TRUE FALSE FALSE 2397.669649 3060.423742 2788.9056 2599.200512 2332.49091 3355.107343 2238.646192 2653.452593 3471.022364 2647.26282 0.905716512 1.156070987 1.053505371 0.981844527 0.881095331 1.267387325 0.845645614 1.002338179 1.311174069 1 11.37028572 TLSNAEDYLDDEDS(ph)D ddPTM_HeLa_Curcumin_4h_R1 5 TLSNAEDYLDDEDSD 15 0 Q92882 Q92882 OSTF1 Osteoclast-stimulating factor 1 1 0 TLSNAEDYLDDEDS(1)D;TLSNAEDYLDDEDS(1)D;TLSNAEDYLDDEDS(1)D;TLSNAEDYLDDEDS(1)D;TLSNAEDYLDDEDS(1)D ;;;; 306.14 1.85E-92 343961600 25097.57 21844.3 21359.44 22774.19 22202.88 27958.73 20270.95 13953.58 26596.57 22420.94 TRUE FALSE FALSE 23111.07085 23732.42396 22151.03964 22679.95644 21938.12516 22159.77424 20839.6983 18207.96231 23678.99281 23200.066 0.996164013 1.022946398 0.954783475 0.977581548 0.945606153 0.955159966 0.898260303 0.784823729 1.020643339 1 14.50184129 -2.991329346 0.585807187 0.997703089 3.64E-17 0.919313252 0.019143493 2.17378088 0.165827099 0.003048642 2.068997708 0.001020166 2.991329346 -0.997703089 TLSNAEDYLDDEDSD ddPTM_HeLa_Curcumin_4h_R1 2 TLSNAEDYLDDEDSD 15 0 Q92882 Q92882 OSTF1 Osteoclast-stimulating factor 1 0 0 ; ; 206.97 1.11E-08 20930500 10708 8648.8 9133.3 9188.3 9084.4 10551.2 5426.8 4726.1 10408.3 8478.1 FALSE FALSE TRUE 9860.450501 9396.363734 9471.788132 9150.281249 8976.074463 8362.762183 5579.061403 6167.066134 9266.53553 8772.713344 1.123990961 1.071089795 1.079687408 1.043038897 1.023181097 0.953269742 0.635956196 0.702982748 1.056290701 1 13.09880741 -4.885826519 3.07874503 1.058251571 0.66384608 0.941432693 0.037928347 0.052156821 0.9712597 0.007372831 0.027015359 1.30E-05 4.885826519 -0.39440549 TSQCSSPSLSAS(ph)PGS(ph)PTRPQIR ddPTM_HeLa_Curcumin_4h_R1 1 TSQCSSPSLSASPGSPTRPQIR 22 1 P37275-3;P37275-4;P37275-5;P37275;P37275-2;H0YMD3;H0YND9 P37275-3 ZEB1 Zinc finger E-box-binding homeobox 1 2 0 T(0.017)S(0.02)QCS(0.177)S(0.209)PS(0.111)LS(0.001)AS(0.457)PGS(0.969)PT(0.039)RPQIR 75.43 0.0010762 21692000 1505.3 1202.2 1365.3 1167.4 1280.5 1402.4 1037.9 400.81 1597 1407.8 TRUE FALSE FALSE 1386.153917 1306.112811 1415.899219 1162.569608 1265.230874 1111.526432 1067.020681 523.0151239 1421.813095 1456.720945 0.951557621 0.896611541 0.971976976 0.798072968 0.868547183 0.763033191 0.732481183 0.359035906 0.976036694 1 10.50850882 -4.066922628 0.57519773 0.971519163 3.95E-24 0.882299841 0.062121539 0.962170724 0.184735525 0.011056664 0.652244712 8.57E-05 4.066922628 -0.971519163 down TLSPT(ph)PSAEGYQDVRDR ddPTM_HeLa_Curcumin_4h_R1 1 TLSPTPSAEGYQDVRDR 17 1 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4;A0A494C1P1;A0A494C1G0;H0Y7N6;F6XFR5 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 T(0.001)LS(0.036)PT(0.935)PS(0.029)AEGYQDVRDR 88.471 0.0041421 70478000 1073.8 711.04 588.19 661.63 610.45 795.06 578.51 540.05 1405.4 948.45 TRUE FALSE FALSE 988.8075969 772.4991293 609.9888388 658.8923504 603.1707824 630.1555938 594.7414336 704.7087589 1251.231136 981.4085669 1.007539194 0.787133061 0.621544237 0.671374158 0.614597022 0.642093023 0.606007991 0.718058495 1.274933986 1 9.938710055 -7.077142914 2.677008947 1.004599855 0.643464228 0.818878949 0.091329589 0.030747874 0.431193845 0.005104234 0.006457491 8.37E-08 7.077142914 -0.361135627 S(ph)TEPSVTPDLLNFK ddPTM_HeLa_Curcumin_4h_R1 2 STEPSVTPDLLNFK 14 0 A0A494BZV2;Q6WCQ1;Q6WCQ1-2 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 S(0.852)T(0.148)EPSVTPDLLNFK;S(0.963)T(0.037)EPSVTPDLLNFK ; 195.87 3.15E-06 12920100 3825.8 3455.1 3570.5 3691.8 3480.7 4276.9 2863.1 1255.78 4030.3 3387.1 TRUE FALSE FALSE 3522.983893 3753.743448 3702.825871 3676.52431 3439.194926 3389.822729 2943.43088 1638.661541 3588.186173 3504.801473 1.00518786 1.071028838 1.056500889 1.048996452 0.981280952 0.967193935 0.839828134 0.467547607 1.023791562 1 11.77511701 -4.066483644 1.356057233 1.014591249 0.019068573 0.974024224 0.027578661 0.247452744 0.282720205 0.004652601 0.381188537 8.58E-05 4.066483644 -0.995522676 down TLSPTPASATAPTS(ph)QGIPTSDEES(ph)TPKK ddPTM_HeLa_Curcumin_4h_R1 1 TLSPTPASATAPTSQGIPTSDEESTPKK 28 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 2 0 TLSPTPASAT(0.01)APT(0.073)S(0.388)QGIPT(0.273)S(0.285)DEES(0.522)T(0.448)PKK 90.858 1.31E-07 14254000 3712.4 2509.4 3268.5 3649.2 4068.3 5372.9 4458.5 1600.6 3573.8 2785.3 TRUE FALSE FALSE 3418.559623 2726.301354 3389.633485 3634.100577 4019.78818 4258.499975 4583.593511 2088.615572 3181.763081 2882.088968 1.186139519 0.945946286 1.176103001 1.260925883 1.394748124 1.477574087 1.59037197 0.724688098 1.103978093 1 11.49289916 -6.308536756 2.683071464 1.079542681 1.328199189 0.179409791 0.22365455 0.327922843 4.657271826 0.033678288 0.055530513 4.91E-07 6.308536756 0.248656507 TLSPTPASATAPTSQGIPT(ph)SDEESTPKK ddPTM_HeLa_Curcumin_4h_R1 1 TLSPTPASATAPTSQGIPTSDEESTPKK 28 1 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 TLSPTPASATAPTSQGIPT(0.499)S(0.499)DEES(0.001)T(0.001)PKK 85.777 3.07E-06 19139000 1413.2 1145.7 1319.9 1504.6 1785.5 2456.5 1958.7 1711.4 1383.5 1079.6 TRUE FALSE FALSE 1301.343729 1244.729203 1368.816655 1498.374364 1764.209079 1946.99421 2013.65585 2233.197982 1231.733511 1117.11602 1.164913676 1.114234494 1.225312887 1.341288047 1.579253227 1.742875561 1.80254854 1.999074351 1.102601243 1 10.12556331 -5.287945323 0.525488914 1.050821606 2.170104768 0.981331028 0.045098622 0.184285837 0.064014697 0.012419012 0.104885337 5.15E-06 5.287945323 1.119283162 TLSS(ph)PSNRPSGETSVPPPPAVGR ddPTM_HeLa_Curcumin_4h_R1 1 TLSSPSNRPSGETSVPPPPAVGR 23 1 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 0 T(0.013)LS(0.204)S(0.38)PS(0.132)NRPS(0.132)GET(0.07)S(0.07)VPPPPAVGR 56.292 0.0049248 153830000 877.95 650.02 970.4 968.84 907.06 1066.2 1040.8 678.22 966.03 793.28 TRUE FALSE FALSE 808.4593311 706.2048324 1006.363878 964.8311968 896.2439019 845.0581014 1070.002047 885.0061559 860.0589259 820.846421 0.98490937 0.860337347 1.226007511 1.175410128 1.091853335 1.029495993 1.303535009 1.078162898 1.047770818 1 9.680968511 -6.751443543 24.99968017 0.982734514 1.15062223 0.509056997 0.085187493 124.3741738 311060.1021 0.012471823 0.017518651 1.77E-07 6.751443543 0.167887717 TLSSPS(ph)NRPSGETSVPPPPAVGR ddPTM_HeLa_Curcumin_4h_R1 2 TLSSPSNRPSGETSVPPPPAVGR 23 1 Q8WWM7-6;Q8WWM7-8;Q8WWM7-5;Q8WWM7-4;Q8WWM7-9;Q8WWM7-2;Q8WWM7;Q8WWM7-3 Q8WWM7-6 ATXN2L Ataxin-2-like protein 1 0 TLS(0.01)S(0.033)PS(0.358)NRPS(0.304)GET(0.177)S(0.117)VPPPPAVGR;TLS(0.001)S(0.005)PS(0.574)NRPS(0.381)GET(0.019)S(0.019)VPPPPAVGR ; 102.07 1.69E-05 136322000 2413.32 2018.82 2154.9 2237.21 2101.86 2951.36 2236.08 1238.06 2698.58 1834.26 TRUE FALSE FALSE 2222.303175 2193.317805 2234.76249 2227.953018 2076.796692 2339.214667 2298.818387 1615.538795 2402.552526 1898.000398 1.170865495 1.155593965 1.177429937 1.173842229 1.094202453 1.232462685 1.211179085 0.851179376 1.26583352 1 10.89026458 -9.297123565 0.975024408 0.998288183 1.142914162 0 0.130580963 0.668930103 1.118422746 0.068467831 0.017518125 5.05E-10 9.297123565 0.144625978 TLSSS(ph)SMDLSR ddPTM_HeLa_Curcumin_4h_R1 1 TLSSSSMDLSR 11 0 Q9H0B6;Q9H0B6-2 Q9H0B6 KLC2 Kinesin light chain 2 1 0 TLS(0.002)S(0.238)S(0.521)S(0.238)MDLSR 103.14 0.0092454 60962000 1536.8 1340.8 1241.4 1627.6 1403.5 2021.9 1429.8 1715.6 1829.7 1583.2 TRUE FALSE FALSE 1415.160658 1456.692778 1287.407376 1620.865422 1386.764179 1602.535148 1469.91634 2238.678542 1628.986488 1638.216082 0.863842489 0.889194529 0.78585932 0.989408809 0.846508708 0.978219641 0.897266457 1.366534346 0.99436607 1 10.67790995 -4.259666597 24.92097782 0.919962133 1.366534502 0.791234107 0.069389418 52.81212626 742344 0.010021353 0.086061372 5.50E-05 4.259666597 0.446572369 TLSSSS(ph)MDLSR ddPTM_HeLa_Curcumin_4h_R1 1 TLSSSSMDLSR 11 0 Q9H0B6;Q9H0B6-2 Q9H0B6 KLC2 Kinesin light chain 2 1 0 TLS(0.004)S(0.027)S(0.181)S(0.788)MDLSR 104.43 0.010222 31329000 4271.6 3932.8 4590.9 4813 4879 5948.3 4760.7 5689.3 4893.2 5124.5 TRUE FALSE FALSE 3933.498353 4272.733708 4761.042793 4793.085081 4820.821112 4714.555529 4894.272429 7423.94138 4356.428202 5302.575994 0.741808954 0.805784531 0.897873562 0.903916339 0.90914701 0.889106641 0.922999017 1.400063175 0.821568273 1 12.37247768 -4.254749246 3.711364555 0.877044495 1.459754223 0.849729433 0.06627806 0.111996742 2.842618863 0.013429897 0.180331651 5.56E-05 4.254749246 0.582709728 S(ph)QDVELWEGEVVK ddPTM_HeLa_Curcumin_4h_R1 1 SQDVELWEGEVVK 13 0 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 S(1)QDVELWEGEVVK 125.86 0.0019662 5999800 1577.3 1249.4 1322.7 1532.1 1933.1 1768.1 1788.9 2180.1 1541.2 1365.3 TRUE FALSE FALSE 1452.455041 1357.392569 1371.720426 1525.760576 1910.049045 1401.376129 1839.091719 2844.802454 1372.134216 1412.744073 1.028109102 0.960819864 0.970961727 1.07999786 1.35201349 0.991953289 1.301786894 2.013671484 0.971254625 1 10.46428442 -1.444177756 0.899673336 1.020801709 199.9998004 0.874632337 0.110496748 81.77828409 0.425378514 0.01663973 33073.32704 0.035960212 1.444177756 198.9789987 up TLSVAAAFNEDEDS(ph)EPEEMPPEAK ddPTM_HeLa_Curcumin_4h_R1 6 TLSVAAAFNEDEDSEPEEMPPEAK 24 0 Q8WW12 Q8WW12 PCNP PEST proteolytic signal-containing nuclear protein 1 0 TLSVAAAFNEDEDS(0.999)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK;TLSVAAAFNEDEDS(1)EPEEMPPEAK ;;;;; 113.29 6.31E-07 362022900 35447.8 32211.13 31118.26 33508.6 32617.1 39418.5 32160.7 31444.1 38299.1 32953.4 TRUE FALSE FALSE 32642.06923 34995.31655 32271.53009 33369.95029 32228.16239 31242.65876 33063.04269 41031.26134 34097.78455 34098.5282 0.95728675 1.026299914 0.94642003 0.978633157 0.945148195 0.916246548 0.969632545 1.203314733 0.999978191 1 15.05742185 -4.260903116 24.99990254 0.973184173 1.203314803 0.839144169 0.030491888 13.06006118 608682.2071 0.004329718 0.034514653 5.48E-05 4.260903116 0.23013063 TLTAEEAEEEWER ddPTM_HeLa_Curcumin_4h_R1 2 TLTAEEAEEEWER 13 0 P35269;M0R0R9 P35269 GTF2F1 General transcription factor IIF subunit 1 0 0 ; ; 196.16 3.04E-05 10452000 998.59 747.66 952.23 866.91 803.92 1111.51 1035.54 911.86 1132.17 698.52 FALSE FALSE TRUE 919.5505478 812.2843989 987.5204815 863.3229561 794.3337791 880.9702967 1064.594465 1189.881916 1007.973784 722.793518 1.27221748 1.123812512 1.366255309 1.194425427 1.098977452 1.218840893 1.472888783 1.646226601 1.394552882 1 9.497439758 -1 0.5125687 1.135043959 19.6148929 0.500191956 0.130083462 49.5089745 0.459932056 0.024631716 996.862872 0.1 1 18.47984894 TLTAEEAEEEWERR ddPTM_HeLa_Curcumin_4h_R1 2 TLTAEEAEEEWERR 14 1 P35269;M0R0R9 P35269 GTF2F1 General transcription factor IIF subunit 1 0 0 ; ; 240.37 2.03E-28 24206000 2603.8 2165.39 2548.8 2574 2339.02 3250.8 2156.3 2065.23 2777.2 2578.69 FALSE FALSE TRUE 2397.706482 2352.556663 2643.26077 2563.34947 2311.128714 2576.547436 2216.799975 2694.90912 2472.548108 2668.299286 0.898589785 0.881668963 0.990616302 0.9606679 0.866142987 0.965614109 0.830791353 1.009972582 0.926638223 1 11.38170478 -9.386624804 1.08490339 1.000474607 0.921722844 0 0.058616843 0.586646209 1.223697972 0.03534445 0.008851597 4.11E-10 9.386624804 -0.078751764 TLTDEVNS(ph)PDSDRR ddPTM_HeLa_Curcumin_4h_R1 3 TLTDEVNSPDSDRR 14 1 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 1 0 TLTDEVNS(1)PDSDRR;TLTDEVNS(0.998)PDS(0.002)DRR;TLTDEVNS(0.926)PDS(0.074)DRR ;; 154.52 0.00019294 558205000 11853.2 9569.9 9819.2 10900.7 10462 12407.4 9834.7 7622.1 11315.7 9066.9 TRUE FALSE FALSE 10915.00671 10397.07951 10183.10819 10855.59579 10337.24748 9833.96538 10110.63521 9946.043202 10074.39602 9381.9741 1.163401923 1.108197422 1.08539078 1.157069469 1.101820083 1.048176564 1.077666076 1.060122645 1.073803436 1 13.1956758 -5.26557234 24.21964514 1.089410106 1.063556195 0.103114913 0.043887186 752.2684537 4408409.895 0.009361153 0.021705048 5.43E-06 5.26557234 -0.025853912 RGNDPLTS(ph)S(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 1 RGNDPLTSSPGR 12 1 P49736;F8WDM3;C9J013;C9JZ21 P49736 MCM2 DNA replication licensing factor MCM2 2 0 RGNDPLT(0.13)S(0.911)S(0.96)PGR 103.11 0.011706 31471000 4599.3 3692.5 4436.3 5089.3 4237.1 5342.3 3649.1 1560.4 4775 5151.6 TRUE FALSE FALSE 4235.260552 4011.663247 4600.713181 5068.241825 4186.57535 4234.24676 3751.483925 2036.158777 4251.194446 5330.617717 0.794515904 0.752570051 0.863073179 0.950779458 0.785382778 0.794325721 0.703761576 0.381974264 0.797505031 1 12.38008701 -4.066335418 1.005933378 0.885538003 1.41E-21 0.758419916 0.077737581 1.080135425 0.653274198 0.014706663 1.126890783 8.58E-05 4.066335418 -0.885538003 down TLTLVDTGIGMTK ddPTM_HeLa_Curcumin_4h_R1 1 TLTLVDTGIGMTK 13 0 P08238 P08238 HSP90AB1 Heat shock protein HSP 90-beta 0 0 195.25 1.92E-13 920520 1831.5 1304.9 1696.7 1837.3 1522.8 1889.7 1370.6 1238 1588 1569.9 FALSE FALSE TRUE 1686.534842 1417.689741 1759.581195 1829.697739 1504.641605 1497.754919 1409.055347 1615.460501 1413.800373 1624.453908 1.038216495 0.872717739 1.083183207 1.126346356 0.926244566 0.92200518 0.867402479 0.994463735 0.870323477 1 10.66573909 -5.577560075 24.99963615 1.018862696 0.92227146 0.122310171 0.082501445 78.23891555 35769.54765 0.00959917 0.019198342 2.65E-06 5.577560075 -0.096591236 TLTRTS(ph)QETADVK ddPTM_HeLa_Curcumin_4h_R1 1 TLTRTSQETADVK 13 1 H3BVG0;Q8N1F7;H3BNN5;H3BV11;H3BRI8;H3BM93 H3BVG0 NUP93 Nuclear pore complex protein Nup93 1 0 T(0.017)LT(0.017)RT(0.232)S(0.732)QET(0.001)ADVK 100.18 0.0061317 0 1274.4 1171.5 935.08 988.93 950.93 1462.3 1050 1037.6 1440.2 1178.6 TRUE FALSE FALSE 1173.529895 1272.75924 969.7348874 984.8380697 939.5907808 1159.002496 1079.460174 1353.959463 1282.213663 1219.556262 0.962259743 1.043624865 0.795153875 0.807538037 0.7704366 0.950347706 0.885125359 1.110206643 1.051377212 1 10.2521406 -6.770840014 24.99989171 0.986288747 0.880448739 0.28343756 0.095225863 220.4804818 586341.2404 0.014920292 0.019754923 1.69E-07 6.770840014 -0.105840008 TLVLLMGK ddPTM_HeLa_Curcumin_4h_R1 4 TLVLLMGK 8 0 P07737;K7EJ44;CON__P02584 P07737 PFN1 Profilin-1 0 0 ;;; ;;; 111.82 0.0054934 15575600 21773.9 8966 16508.5 11466.2 17547.2 20686.5 17007.4 14206.4 13450.7 14915.1 FALSE FALSE TRUE 20050.47284 9740.981088 17120.31953 11418.7559 17337.9611 16395.88672 17484.58187 18537.86596 11975.19186 15433.39861 1.299161211 0.631162412 1.109303269 0.739873063 1.123405255 1.062363976 1.13290548 1.201152541 0.775927076 1 13.91376817 -4.460831123 2.325623674 1.071019705 1.208688137 0 0.212549534 1.287532444 10.84232358 0.029607501 0.298829099 3.46E-05 4.460831123 0.137668431 TLWLFDIDRDPEER ddPTM_HeLa_Curcumin_4h_R1 2 TLWLFDIDRDPEER 14 1 P15848 P15848 ARSB Arylsulfatase B 0 0 ; ; 81.904 0.0088167 5452600 2573.91 1940.71 2775.9 2585.1 2488.6 4707.4 3000.3 2829.1 2988.3 2338.34 FALSE FALSE TRUE 2370.182308 2108.456325 2878.777296 2574.403541 2458.92507 3731.032177 3084.480343 3691.679566 2660.490966 2419.597141 0.979577248 0.871408008 1.189775458 1.063980238 1.016253916 1.542005532 1.274790869 1.525741415 1.099559477 1 11.24055115 -5.272195119 24.26890073 1.003496274 1.430240426 0.761932886 0.105620666 140.333902 316645.1043 0.013628959 0.030781751 5.34E-06 5.272195119 0.426744153 TLYSFFS(ph)PSPAR ddPTM_HeLa_Curcumin_4h_R1 2 TLYSFFSPSPAR 12 0 P13051 P13051 UNG Uracil-DNA glycosylase 1 0 TLYSFFS(0.994)PS(0.006)PAR;TLYS(0.006)FFS(0.988)PS(0.006)PAR ; 177.21 0.0001327 111965000 4979.8 4095.7 4509.8 5032.9 4642.6 4930.7 2857.5 1917.08 4982.3 4260.4 TRUE FALSE FALSE 4585.643575 4449.714058 4676.937155 5012.075193 4587.240027 3908.01724 2937.673759 2501.588867 4435.754155 4408.448583 1.040194411 1.009360544 1.060903188 1.136924952 1.040556545 0.88648357 0.666373602 0.567453339 1.006193919 1 12.10605532 -4.818529502 2.085388204 1.032134816 0.57373934 0.949358908 0.039161759 0.057512839 0.472550527 0.006390592 0.032567744 1.52E-05 4.818529502 -0.458395475 TMCPLLSMKPGEYSYFS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 TMCPLLSMKPGEYSYFSPR 19 1 C9J470;E9PHA2;Q15003;Q15003-2 C9J470 NCAPH Condensin complex subunit 2 1 0 TMCPLLSMKPGEY(0.001)S(0.032)Y(0.002)FS(0.966)PR;TMCPLLSMKPGEYS(0.001)YFS(0.999)PR ; 126.61 6.18E-05 62876000 2643.1 2612.4 2697.8 2575.7 2729.8 5653.6 3726.5 1454.65 3544.8 2532.1 TRUE FALSE FALSE 2433.895846 2838.204215 2797.782841 2565.042436 2697.248918 4480.979631 3831.055561 1898.166089 3155.944309 2620.090287 0.928935869 1.083246722 1.067819249 0.978990094 1.029448844 1.710238633 1.462184559 0.724465908 1.204517388 1 11.35540081 -5.489688247 24.88246144 0.985410344 1.32437836 0.163634205 0.244046753 537.4910372 402949.2779 0.031496913 0.070381859 3.24E-06 5.489688247 0.338968016 TMFAQVES(ph)DDEEAK ddPTM_HeLa_Curcumin_4h_R1 1 TMFAQVESDDEEAK 14 0 Q9NW82 Q9NW82 WDR70 WD repeat-containing protein 70 1 0 TMFAQVES(1)DDEEAK 188.9 7.68E-06 9559300 2456.3 2001.2 2151.4 2310.1 2852.1 2500.4 1996.1 1961.1 1973.6 1767.2 TRUE FALSE FALSE 2261.881263 2174.174811 2231.132777 2300.541418 2818.09057 1981.788855 2052.105194 2559.030362 1757.101018 1828.610068 1.236940178 1.188976725 1.220124954 1.258082003 1.541110715 1.083767879 1.122221314 1.399440157 0.960894314 1 10.83653175 -9.22950624 0.456884197 0.936147497 1.267278258 0.444392018 0.124307272 1.512984878 0.429838075 0.233307565 0.03673391 5.90E-10 9.22950624 0.331130761 TMFAQVES(ph)DDEEAKNEPEWK ddPTM_HeLa_Curcumin_4h_R1 1 TMFAQVESDDEEAKNEPEWK 20 1 Q9NW82 Q9NW82 WDR70 WD repeat-containing protein 70 1 0 T(0.005)MFAQVES(0.995)DDEEAKNEPEWK 64.68 0.0044812 69327000 1674.9 1257 2033 1843.3 1833.5 2041.9 1667.4 1514.2 2071.1 1726.3 TRUE FALSE FALSE 1542.329898 1365.649479 2108.344768 1835.672913 1811.63671 1618.386923 1714.182756 1975.872609 1843.905512 1786.288797 0.863426956 0.764517743 1.180293339 1.027646211 1.014190266 0.906005191 0.959633604 1.10613279 1.032254983 1 10.80274963 -6.762020331 24.99999602 0.920880973 1.022235411 0.251589955 0.097958161 19.99257157 860361.9415 0.016151973 0.021964056 1.73E-07 6.762020331 0.101354438 TMFAQVES(ph)DDEEAKNEPEWKK ddPTM_HeLa_Curcumin_4h_R1 2 TMFAQVESDDEEAKNEPEWKK 21 2 Q9NW82 Q9NW82 WDR70 WD repeat-containing protein 70 1 0 TMFAQVES(1)DDEEAKNEPEWKK;T(0.009)MFAQVES(0.991)DDEEAKNEPEWKK ; 94.057 0.00025427 24519000 2015.36 1357.52 1183.91 1518.58 1373.61 1783.64 1474.55 1280.23 1792.43 1601.01 TRUE FALSE FALSE 1855.842129 1474.85798 1227.786746 1512.296518 1357.230598 1413.692958 1515.921904 1670.566234 1595.804913 1656.644978 1.120241303 0.890267981 0.741128463 0.912866992 0.819264607 0.853346961 0.915055383 1.008403282 0.963275134 1 10.69404875 -7.194875264 6.975186235 1.056677362 0.870944476 0.434141822 0.076592261 0.142004576 12.78978588 0.012932991 0.015843447 6.38E-08 7.194875264 -0.185732886 IGQQVDREPGDVAT(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 1 IGQQVDREPGDVATPPR 17 1 H3BT22;Q9Y5N6 H3BT22 ORC6 Origin recognition complex subunit 6 1 0 IGQQVDREPGDVAT(1)PPR 100.41 0.0017231 221730000 2707.9 2301 2393.9 2471.3 2612.6 2912 1977.6 882.03 2444.9 2571.2 TRUE FALSE FALSE 2493.566858 2499.888187 2482.62004 2461.074415 2581.446451 2308.018375 2033.086134 1150.956887 2176.700587 2660.549009 0.937237709 0.939613658 0.933123213 0.925025026 0.970268333 0.867497034 0.764160377 0.432601272 0.818139632 1 11.37750826 -4.066334721 1.129704619 0.962319072 6.06E-21 0.890999616 0.051917559 0.297553421 0.230034676 0.004748464 0.375308026 8.58E-05 4.066334721 -0.962319072 down TMIVHDDVESEPAMTPS(ph)KEGTLIVR ddPTM_HeLa_Curcumin_4h_R1 1 TMIVHDDVESEPAMTPSKEGTLIVR 25 1 O95819-3;E7EX83;G5E948;C9J840;H7C360;E7ENQ1;H7C0P6;G3XAA2;A0A0D9SG62;A0A0D9SEY1;O95819-4;O95819-2;O95819;O95819-5;O95819-6;E7EN19 O95819-3 MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 1 0 TMIVHDDVES(0.001)EPAMT(0.061)PS(0.883)KEGT(0.054)LIVR 47.991 0.0088332 7233700 776.03 653.09 484.6 770.9 607.4 665.25 715.99 725.51 771.65 607.48 TRUE FALSE FALSE 714.6064066 709.5401895 502.5597023 767.7102201 600.1571517 527.2696511 736.0787524 946.7146592 687.0019256 628.5898848 1.136840449 1.128780794 0.799503324 1.221321308 0.954767435 0.838813452 1.170999996 1.506092736 1.092925518 1 9.295975246 -4.335054225 3.534406601 1.041987644 1.529046132 0.563268456 0.127849258 0.138403245 2.864197834 0.017264961 0.155324508 4.62E-05 4.335054225 0.487058488 TMLLLSRS(ph)PEAQPK ddPTM_HeLa_Curcumin_4h_R1 1 TMLLLSRSPEAQPK 14 1 P55265-5;P55265;P55265-4 P55265-5 ADAR Double-stranded RNA-specific adenosine deaminase 1 0 T(0.016)MLLLS(0.05)RS(0.933)PEAQPK 98.676 0.01146 14296000 3823.6 3004 3067.4 3178.3 2565.3 4015.3 2658.6 1924.1 4577.2 4011.5 TRUE FALSE FALSE 3520.958025 3263.652374 3181.080542 3165.149037 2534.710473 3182.481518 2733.193161 2510.749233 4075.092612 4150.899326 0.848239803 0.786251874 0.766359358 0.762521273 0.610641279 0.766696869 0.65845807 0.604868737 0.981737279 1 12.01920823 -7.181893309 0.208983522 1.088839052 0.535456848 0.886010634 0.043834842 0.553072764 0.103975101 0.104207417 0.122197849 6.58E-08 7.181893309 -0.553382204 TMQAVNK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 TMQAVNKK 8 1 Q9UQN3-2;Q9UQN3;A0A087WW88 Q9UQN3-2 CHMP2B Charged multivesicular body protein 2b 0 1 ; TMQAVNK(1)K;TMQAVNK(1)K 119.21 0.00094737 9825900 3056.6 3007.9 3338.4 2809.73 2855.71 3539.1 3399.7 4279.7 3149.2 3683.7 FALSE TRUE FALSE 2814.666885 3267.889473 3462.124041 2798.104082 2821.657523 2805.050766 3495.086432 5584.560829 2803.740639 3811.708301 0.738426622 0.857329369 0.908286723 0.734081378 0.740260613 0.735903838 0.916934392 1.465107083 0.735560126 1 11.896222 -4.269588242 4.040714115 0.84685934 1.514724872 0.809032033 0.093910608 0.090794402 3.127747161 0.016252938 0.174368187 5.38E-05 4.269588242 0.667865531 TMS(ph)SDDEDCSAK ddPTM_HeLa_Curcumin_4h_R1 1 TMSSDDEDCSAK 12 0 H0YBW3;Q9NVR2 H0YBW3 INTS10 Integrator complex subunit 10 1 0 T(0.007)MS(0.496)S(0.496)DDEDCSAK 116.71 0.0045495 32613000 7930.2 7286.6 8002.5 7435.6 7614.8 7658.1 5712.4 3598.7 8311.2 6792 TRUE FALSE FALSE 7302.516302 7916.421236 8299.07969 7404.833457 7523.998483 6069.723735 5872.67457 4695.927064 7399.482154 7028.021494 1.039057195 1.126408228 1.180855764 1.053615653 1.070571353 0.863646154 0.83560851 0.668171984 1.052854229 1 12.77890289 -4.789556659 1.454626659 1.045561215 0.679515578 0.824009169 0.061569232 0.200388415 0.682473124 0.010477054 0.079913038 1.62E-05 4.789556659 -0.366045637 TMSS(ph)DDEDCSAK ddPTM_HeLa_Curcumin_4h_R1 2 TMSSDDEDCSAK 12 0 H0YBW3;Q9NVR2 H0YBW3 INTS10 Integrator complex subunit 10 1 0 T(0.001)MS(0.159)S(0.839)DDEDCSAK;TMS(0.051)S(0.949)DDEDCSAK ; 133.88 0.001972 79001000 12950.2 10898.5 12194.7 11583.2 11621 12469.4 8961 5773.4 12436.6 11240.7 TRUE FALSE FALSE 11925.17801 11840.51778 12646.64631 11535.27179 11482.42716 9883.105881 9212.421543 7533.683083 11072.33609 11631.31349 1.025264947 1.0179863 1.087293049 0.991742833 0.987199526 0.849698178 0.792036218 0.647706993 0.951942023 1 13.5057264 -4.724106652 1.075668747 1.018914108 0.608137098 0.919206512 0.035834385 0.142410094 0.209656819 0.004571682 0.055072018 1.89E-05 4.724106652 -0.41077701 TNATSPGVNSST(ph)SPQSTDK ddPTM_HeLa_Curcumin_4h_R1 2 TNATSPGVNSSTSPQSTDK 19 0 B7ZM87;O75044 B7ZM87 SRGAP2 SLIT-ROBO Rho GTPase-activating protein 2 1 0 TNATSPGVNSS(0.001)T(0.996)S(0.002)PQSTDK;TNATSPGVNS(0.01)S(0.01)T(0.659)S(0.319)PQS(0.001)TDK ; 224.99 1.56E-19 30910800 6951.9 6129.8 6169.7 6202.3 6370.5 6816.9 3604.4 3132.5 6433.2 5146.3 TRUE FALSE FALSE 6401.649779 6659.632598 6398.354509 6176.636526 6294.535948 5402.998098 3705.529763 4087.58483 5727.494055 5325.133542 1.202157604 1.250603867 1.201538789 1.159902654 1.182042835 1.014622085 0.695856683 0.767602314 1.075558765 1 12.37860199 -4.880474578 3.790548301 1.126936526 0.730530282 0.835041764 0.073241639 0.087086822 2.330421962 0.014118081 0.047977862 1.32E-05 4.880474578 -0.396406244 TNEAQAIETAR ddPTM_HeLa_Curcumin_4h_R1 1 TNEAQAIETAR 11 0 P61088;Q5JXB2;F8VQQ8 P61088 UBE2N;UBE2NL Ubiquitin-conjugating enzyme E2 N;Putative ubiquitin-conjugating enzyme E2 N-like 0 0 97.779 0.012751 3071500 2174.2 1288.2 1646 1452.1 1613.3 2166.3 1647.4 1355.5 1619.3 1508 FALSE FALSE TRUE 2002.109776 1399.546268 1707.002208 1446.091595 1594.062451 1716.984961 1693.62161 1768.78571 1441.666841 1560.402888 1.283072334 0.896913405 1.09394966 0.92674245 1.021571072 1.100347208 1.085374568 1.133544243 0.923906802 1 10.60770286 -7.258610385 24.99480072 1.133673045 1.038588959 0 0.116252322 419.1724466 3703478.421 0.020756383 0.024837123 5.51E-08 7.258610385 -0.095084085 TNEK(ac)VELQELNDR ddPTM_HeLa_Curcumin_4h_R1 1 TNEKVELQELNDR 13 1 P08670;B0YJC4;A0A1B0GTT5;P17661 P08670 VIM;DES Vimentin;Desmin 0 1 TNEK(1)VELQELNDR 283.47 1.57E-94 12544000 1812.8 2368.1 1761.6 1479.7 2729 4610.2 3475 3039.7 4927.8 1970.8 FALSE TRUE FALSE 1669.314967 2572.788012 1826.886446 1473.577393 2696.458457 3653.992552 3572.499148 3966.490537 4387.232669 2039.285153 0.818578493 1.261612682 0.895846489 0.722595068 1.3222567 1.791800694 1.751838943 1.945039678 2.151358118 1 10.99384781 -5.435208966 2.853214141 0.92818584 1.829804978 0.280305132 0.41244937 0.063437368 0.998639088 0.021599861 0.052590245 3.67E-06 5.435208966 0.901619138 TNEKVELQELNDR ddPTM_HeLa_Curcumin_4h_R1 4 TNEKVELQELNDR 13 1 P08670;B0YJC4;A0A1B0GTT5;P17661 P08670 VIM;DES Vimentin;Desmin 0 0 ;;; ;;; 177.36 0.0012426 138630500 6347.06 5068.2 4895.28 5192 4677.83 7600.73 6309.68 5585.52 7393.98 6275.84 FALSE FALSE TRUE 5844.683504 5506.272625 5076.703383 5170.51688 4622.049932 6024.25292 6486.712639 7288.519335 6582.878893 6493.924973 0.900023257 0.84791134 0.78176194 0.796208287 0.71174982 0.927675165 0.998889372 1.122359646 1.013698021 1 12.664875 -4.472041125 2.424649992 0.902480941 1.128382452 0.394817943 0.093615889 0.37689413 3.568575215 0.015562384 0.144834545 3.37E-05 4.472041125 0.225901511 TNELINISS(ph)S(ph)KT(ph)NAILSR ddPTM_HeLa_Curcumin_4h_R1 1 TNELINISSSKTNAILSR 18 1 Q13439-3;Q13439-4;Q13439;Q13439-5;H0Y6I0 Q13439-3 GOLGA4 Golgin subfamily A member 4 3 0 T(0.001)NELINIS(0.257)S(0.847)S(0.895)KT(0.828)NAILS(0.172)R 61.165 0.0081328 0 2495.5 3425.3 2560.4 2057.5 2873.5 5197.8 3474.8 2832.1 3865.2 4605.6 TRUE FALSE FALSE 2297.978542 3721.367669 2655.290676 2048.98661 2839.235389 4119.717689 3572.293536 3695.594253 3441.19723 4765.644257 0.482196827 0.780873995 0.557173497 0.429949551 0.595771576 0.864461858 0.749592992 0.775465824 0.72208437 1 12.21845555 -9.490001739 1.213782262 1.001439878 0.637459127 0.127744054 0.157302476 0.342624751 0.897481049 0.104376453 0.02502147 3.24E-10 9.490001739 -0.363980751 TNGHS(ph)PSQPR ddPTM_HeLa_Curcumin_4h_R1 1 TNGHSPSQPR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 TNGHS(0.78)PS(0.219)QPR 99.161 0.0062055 5279300 1806.8 4022.8 1167.8 1362.2 1081.6 943.94 492.67 620.2 986.79 1343.5 TRUE FALSE FALSE 1663.789873 4370.512907 1211.079695 1356.563577 1068.702626 748.1562036 506.4929942 809.296125 878.5416058 1390.186525 1.196810531 3.143832017 0.871163454 0.975814075 0.768747652 0.538169656 0.364334559 0.582149309 0.631959518 1 10.44106275 -5.781347229 1.751947675 1.258892385 0.491697917 0.254963637 0.647785511 0.426378682 2.655062216 0.099938855 0.228326209 1.65E-06 5.781347229 -0.767194468 TNGHSPS(ph)QPR ddPTM_HeLa_Curcumin_4h_R1 1 TNGHSPSQPR 10 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 T(0.01)NGHS(0.361)PS(0.629)QPR 82.925 0.013332 4467800 1693.2 4113.7 1284.8 1337.8 1024.5 920.54 668.58 426.15 1105.4 1328.6 TRUE FALSE FALSE 1559.181433 4469.269898 1332.415818 1332.264538 1012.283507 729.6096274 687.3385554 556.0811732 984.1403856 1374.768751 1.134140874 3.250924851 0.969192686 0.969082645 0.736330023 0.53071444 0.499966671 0.404490699 0.715858856 1 10.42497325 -5.786574458 1.897467666 1.249850434 0.490959276 0.263747074 0.667808758 0.428492127 3.137967604 0.104845523 0.232715709 1.63E-06 5.786574458 -0.758891158 GEPAAAAAPEAGAS(ph)PVEK ddPTM_HeLa_Curcumin_4h_R1 4 GEPAAAAAPEAGASPVEK 18 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 GEPAAAAAPEAGAS(1)PVEK;GEPAAAAAPEAGAS(1)PVEK;GEPAAAAAPEAGAS(1)PVEK;GEPAAAAAPEAGAS(1)PVEK ;;; 212.55 1.84E-13 378767900 12638 12114 13888.5 12621.8 18541.6 19166.4 21718.5 32371.2 10780.5 10497.1 TRUE FALSE FALSE 11637.68896 13161.08018 14403.22003 12569.57434 18320.50353 15191.07259 22327.86266 42241.02986 9597.906121 10861.87344 1.071425572 1.211676811 1.326034602 1.157219738 1.686679892 1.398568366 2.055618009 3.88892672 0.88363266 1 13.40698534 -1.419778645 0.717478822 1.079596507 200 0.952830412 0.182475813 20.09506571 0.181894568 0.028886079 6314.226579 0.038038322 1.419778645 198.9204035 up TNLTSQSSTTNLPGSPGS(ph)PGSPGS(ph)PGSPGSVPK ddPTM_HeLa_Curcumin_4h_R1 1 TNLTSQSSTTNLPGSPGSPGSPGSPGSPGSVPK 33 0 Q6IN85-4;Q6IN85-2;Q6IN85 Q6IN85-4 SMEK1 Serine/threonine-protein phosphatase 4 regulatory subunit 3A 2 0 TNLTSQSSTTNLPGS(0.19)PGS(0.456)PGS(0.362)PGS(0.482)PGS(0.329)PGS(0.182)VPK 98.95 1.42E-10 6649900 1586.9 1319.4 1538.9 1813.8 1494 1635.5 1503.6 558.64 1570.2 1508.7 TRUE FALSE FALSE 1461.295191 1433.443057 1595.932988 1806.294976 1476.185026 1296.278864 1545.786969 728.9667643 1397.952988 1561.127213 0.936051322 0.918210281 1.022295284 1.157045346 0.945589196 0.830348003 0.990173611 0.466948983 0.895476664 1 10.60837239 -4.260178716 24.95874803 0.971889955 0.466948817 0.765318676 0.082872461 36.63835014 725283.1715 0.011172316 0.092839629 5.49E-05 4.260178716 -0.504941139 TNNNQILEVKS(ph)PIK ddPTM_HeLa_Curcumin_4h_R1 1 TNNNQILEVKSPIK 14 1 P42568-2;P42568;A0A0D9SF09;B1APT5 P42568-2 MLLT3 Protein AF-9 1 0 TNNNQILEVKS(1)PIK 73.877 0.011927 119300000 2363.7 2286 1867.4 2783 2984.4 2782.7 2847.3 1381.7 2613.8 1973.2 TRUE FALSE FALSE 2176.610651 2483.591654 1936.607487 2771.484683 2948.812979 2205.536653 2927.187575 1802.973969 2327.072679 2041.768553 1.066041813 1.216392353 0.948495109 1.357394147 1.444244488 1.080208944 1.433652982 0.883045224 1.139733823 1 10.99560362 -6.263051147 24.99964167 1.04317744 1.252985765 0.17444774 0.172484163 139.9361397 2170511.245 0.023782149 0.037509829 5.46E-07 6.263051147 0.209808325 TNNNQILEVKS(ph)PIKQSK ddPTM_HeLa_Curcumin_4h_R1 1 TNNNQILEVKSPIKQSK 17 2 P42568-2;P42568;A0A0D9SF09;B1APT5 P42568-2 MLLT3 Protein AF-9 1 0 T(0.008)NNNQILEVKS(0.987)PIKQS(0.005)K 54.004 0.013293 62918000 4022.2 2812.5 2983.3 3136.7 2630.5 3759.3 2587.2 2465.4 3941.3 3470.2 TRUE FALSE FALSE 3703.838626 3055.599968 3093.863722 3123.721167 2599.133006 2979.578804 2659.789869 3217.089111 3508.949251 3590.789192 1.031483172 0.850954986 0.861611071 0.86992608 0.72383336 0.829783829 0.740725709 0.895928148 0.977208369 1 11.81008524 -7.17070318 3.484527251 1.015221192 0.817082409 0.703554619 0.052958067 0.083198251 1.915933598 0.008533321 0.010469447 6.75E-08 7.17070318 -0.198138784 TNNPQFDEVFYFEVTRPCS(ph)YSK ddPTM_HeLa_Curcumin_4h_R1 1 TNNPQFDEVFYFEVTRPCSYSK 22 1 Q14644-2;Q14644 Q14644-2 RASA3 Ras GTPase-activating protein 3 1 0 TNNPQFDEVFY(0.002)FEVT(0.181)RPCS(0.52)Y(0.115)S(0.181)K 69.765 0.0010907 9030500 391.29 184.46 249.44 532.79 244.38 724.93 307.12 231.85 438.47 395.71 TRUE FALSE FALSE 360.3189836 200.4039005 258.6844658 530.5854562 241.4659281 574.5713464 315.7369606 302.5399977 390.370938 409.460893 0.879983876 0.489433555 0.631768431 1.295814729 0.589716704 1.403238639 0.771104069 0.738873975 0.953377831 1 8.677581859 -4.554230297 24.9993976 0.918115507 0.746928048 0.044409767 0.275876274 390.1468792 311098.3315 0.03587901 0.134249133 2.79E-05 4.554230297 -0.171187459 TNPS(ph)PTNPFSSDLQK ddPTM_HeLa_Curcumin_4h_R1 1 TNPSPTNPFSSDLQK 15 0 G3V3Z8;P49757-9;P49757-8;P49757-7;P49757-6;P49757-5;P49757-4;P49757-2;P49757-3;P49757 G3V3Z8 NUMB Protein numb homolog 1 0 T(0.096)NPS(0.83)PT(0.074)NPFSSDLQK 249.86 8.09E-39 17475000 2199.8 1915.4 2085.2 2206.3 1879.6 2430.7 2229.9 1656.4 2300 2020.4 TRUE FALSE FALSE 2025.683509 2080.958641 2162.479346 2197.170915 1857.186998 1926.54542 2292.464993 2161.428735 2047.695754 2090.60875 0.968944337 0.995384068 1.034377832 1.050971836 0.888347472 0.921523657 1.096553811 1.033875294 0.979473445 1 11.02970738 -7.006011959 24.38421281 0.98516795 1.002671179 0.026101516 0.057703001 918.2957 3724587.781 0.009857856 0.0127028 9.86E-08 7.006011959 0.017503229 TNPSPT(ph)NPFSSDLQK ddPTM_HeLa_Curcumin_4h_R1 1 TNPSPTNPFSSDLQK 15 0 G3V3Z8;P49757-9;P49757-8;P49757-7;P49757-6;P49757-5;P49757-4;P49757-2;P49757-3;P49757 G3V3Z8 NUMB Protein numb homolog 1 0 T(0.007)NPS(0.451)PT(0.542)NPFSSDLQK 206.13 4.29E-09 17180000 4106.4 3366.6 3536.4 3622.2 4089.6 5196.4 3405.5 2542.3 4229.3 3812.6 TRUE FALSE FALSE 3781.374107 3657.593903 3667.462095 3607.212296 4040.834191 4118.608065 3501.049165 3317.435567 3765.356371 3945.087566 0.958501945 0.927126164 0.929627552 0.914355445 1.024269835 1.043983941 0.887445236 0.840902898 0.954441773 1 11.94584161 -5.235764701 0.010373921 1.874937263 3.04E-05 0.091620213 0.056327223 5039.863774 11.83774542 1015.994685 1125.015455 5.81E-06 5.235764701 -1.874906865 TNQELQEINR ddPTM_HeLa_Curcumin_4h_R1 4 TNQELQEINR 10 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YNP5;H0YN28;H0YKS4;H0YL33;H0YMM1;H0YNA0;H0YN52;H0YLE2;P07355-2 P07355;P07355-2 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 0 ;;; ;;; 219.5 5.19E-16 189524000 8655.3 6559.2 7523.86 8770.3 7529.01 11191.1 9275.9 8758.3 10000.9 7294.97 FALSE FALSE TRUE 7970.223872 7126.148021 7802.70087 8734.010822 7439.231473 8869.93971 9536.156789 11428.66535 8903.826291 7548.469665 1.055872809 0.944052018 1.033679834 1.157057153 0.985528432 1.17506463 1.263323192 1.514037396 1.179553828 1 12.88196847 -3.385075078 0.69401937 1.022073221 2.838507558 0.788359246 0.073835707 1.807741493 0.252721571 0.008848066 3.439244205 0.000412026 3.385075078 1.816434336 TNS(ph)TGGS(ph)SGSSVGGGSGK ddPTM_HeLa_Curcumin_4h_R1 2 TNSTGGSSGSSVGGGSGK 18 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-5;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 2 0 T(0.137)NS(0.776)T(0.086)GGS(0.892)S(0.089)GS(0.017)S(0.003)VGGGSGK;T(0.132)NS(0.827)T(0.041)GGS(0.661)S(0.262)GS(0.068)S(0.009)VGGGSGK ; 124.2 0.00064552 3759000 4541.7 4817.3 5610.5 4950 5258 3662.3 2465.6 1777.38 3362.2 4860.3 TRUE FALSE FALSE 4182.219653 5233.685947 5818.430065 4929.518212 5195.301784 2902.697697 2534.7781 2319.29498 2993.375072 5029.195063 0.831588276 1.040660758 1.15693068 0.980180357 1.03302849 0.57716944 0.504012684 0.46116624 0.595199636 1 12.2961118 -5.169990443 4.424150209 0.957192427 0.496503349 0.66011929 0.143261877 0.077083785 2.637144415 0.015434322 0.041157843 6.76E-06 5.169990443 -0.460689078 TNS(ph)TGGSSGSSVGGGSGK ddPTM_HeLa_Curcumin_4h_R1 1 TNSTGGSSGSSVGGGSGK 18 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-5;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 0 T(0.066)NS(0.423)T(0.423)GGS(0.01)S(0.039)GS(0.012)S(0.027)VGGGSGK 185.09 3.03E-07 13212000 3363.9 3500.4 3388.5 2892.7 3291.1 2291 2081.4 1696.2 2248.2 2565.9 TRUE FALSE FALSE 3097.643765 3802.958979 3514.080791 2880.730774 3251.855782 1815.820775 2139.798482 2213.363572 2001.578085 2655.064834 1.166692325 1.432341286 1.323538599 1.084994512 1.224774529 0.683908262 0.805930784 0.833638239 0.753871642 1 11.37453138 -5.261857528 24.99997276 1.135351599 0.777636254 0.47469592 0.176550432 22.43905367 1341625.552 0.022148983 0.052583332 5.47E-06 5.261857528 -0.357715345 TPQGPVSATVEVS(ph)SPTGFAQSQVLEDVSQAAR ddPTM_HeLa_Curcumin_4h_R1 1 TPQGPVSATVEVSSPTGFAQSQVLEDVSQAAR 32 0 O15061;H0YL34;A0A075B7B1;O15061-2 O15061 SYNM Synemin 1 0 TPQGPVS(0.002)AT(0.014)VEVS(0.832)S(0.143)PT(0.009)GFAQSQVLEDVSQAAR 110.41 1.03E-11 5911000 518.68 343.26 571.5 598.47 763.75 879.5 873.34 1212.4 614.09 668.52 TRUE FALSE FALSE 477.6259307 372.9298649 592.6802927 595.9936897 754.6427801 697.081786 897.8435699 1582.055179 546.7258634 691.7510202 0.690459308 0.53910996 0.85678268 0.861572549 1.090916758 1.007706191 1.297928798 2.287029773 0.790350643 1 9.434109056 -1.358252851 0.806674933 0.830137817 199.9999988 0.915651218 0.133962775 62.27890193 0.381009202 0.026282751 22440.49662 0.043827545 1.358252851 199.169861 up TNSMSSSGLGS(ph)PNR ddPTM_HeLa_Curcumin_4h_R1 1 TNSMSSSGLGSPNR 14 0 F8VQD8;A0A087X050;F8VVY1;F8VX63;F8VUB4;F8VV52;F8VP97;Q9NZN8-4;Q9NZN8-5;Q9NZN8 F8VQD8 CNOT2 CCR4-NOT transcription complex subunit 2 1 0 TNSMSSSGLGS(1)PNR 185.86 4.63E-05 254600000 2275.2 2206.8 2153 2124.4 1971.8 2603.2 2028.1 837.89 2639.3 1964.7 TRUE FALSE FALSE 2095.115519 2397.545959 2232.792074 2115.609796 1948.287573 2063.266976 2085.003028 1093.358804 2349.775393 2032.973179 1.030567221 1.179329852 1.098288997 1.040648159 0.958343963 1.014901228 1.025592983 0.537812705 1.15583197 1 10.98937547 -4.26136944 7.71199743 1.030044039 0.533063616 0.827385219 0.070108383 0.026873317 16.90159527 0.008635273 0.069026965 5.48E-05 4.26136944 -0.496980423 TNSPAY(ph)SDISDAGEDGEGKVDSVK ddPTM_HeLa_Curcumin_4h_R1 1 TNSPAYSDISDAGEDGEGKVDSVK 24 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 0 T(0.004)NS(0.1)PAY(0.693)S(0.168)DIS(0.034)DAGEDGEGKVDSVK 67.11 0.0051289 15266000 1269.5 1018 1101.7 1164.9 1296.7 1543.6 933.35 500.77 1163.6 1114.7 TRUE FALSE FALSE 1169.017735 1105.991384 1142.529971 1160.079952 1281.237699 1223.43996 959.537289 653.4524677 1035.955991 1153.435742 1.013509199 0.958866926 0.990544969 1.005760365 1.110801107 1.06069191 0.831894881 0.56652698 0.898147988 1 10.17172192 -4.414148681 2.656377368 1.012012757 0.543300369 0.856042387 0.055343435 0.071385712 0.7890466 0.006219463 0.062307326 3.85E-05 4.414148681 -0.468712388 SNVSSPAT(ph)PT(ph)ASSSSSTTPTRK ddPTM_HeLa_Curcumin_4h_R1 1 SNVSSPATPTASSSSSTTPTRK 22 1 A6NNK5;Q12888;Q12888-3;Q12888-2;H7BZY0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 2 0 S(0.001)NVS(0.003)S(0.011)PAT(0.473)PT(0.596)AS(0.304)S(0.249)S(0.092)S(0.073)S(0.066)T(0.061)T(0.056)PT(0.016)RK 61.139 0.0031339 24532000 3439 2559.8 2594.1 2490.5 2532.7 3445.9 2474.7 937.9 3476.4 2675 TRUE FALSE FALSE 3166.799521 2781.057706 2690.239628 2480.194971 2502.499207 2731.181497 2544.133422 1223.861392 3095.047618 2767.956051 1.144093137 1.004733332 0.971922812 0.896038422 0.904096438 0.986714184 0.91913794 0.442153477 1.118170795 1 11.43460532 -4.06597807 1.537858828 1.033257008 2.35E-31 0.814161712 0.079006144 0.650403092 0.974576999 0.013888645 1.164672763 8.59E-05 4.06597807 -1.033257008 down TNSS(ph)SSSPVVLK ddPTM_HeLa_Curcumin_4h_R1 1 TNSSSSSPVVLK 12 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 0 TNS(0.021)S(0.609)S(0.177)S(0.177)S(0.015)PVVLK 191.01 5.33E-06 49157000 3666.6 2952.9 3335.1 3319.9 3234.9 3846.7 3178.5 1784.6 3787.6 3370.1 TRUE FALSE FALSE 3376.384741 3208.135518 3458.70174 3306.163133 3196.32593 3048.851059 3267.680156 2328.716325 3372.109756 3487.210724 0.968219304 0.919971797 0.991824703 0.948082406 0.916585255 0.874295046 0.937046945 0.66778767 0.9669934 1 11.76785783 -3.399750802 0.720245022 0.976909197 3.50E-38 0.79161556 0.041556946 2.554377869 0.380964201 0.006671439 2.717999694 0.000398336 3.399750802 -0.976909197 TNSSS(ph)SSPVVLK ddPTM_HeLa_Curcumin_4h_R1 1 TNSSSSSPVVLK 12 0 E9PMC9;Q7Z589-6;Q7Z589;Q7Z589-5;Q7Z589-4;Q7Z589-7;Q7Z589-2 E9PMC9 C11orf30;EMSY Protein EMSY 1 0 T(0.013)NS(0.024)S(0.106)S(0.3)S(0.3)S(0.257)PVVLK 175.6 0.00014209 49150000 2810.6 2103.7 2296.1 2573.7 2328.8 2447.8 2206.2 1347 2637.8 2527.1 TRUE FALSE FALSE 2588.138044 2285.534454 2381.195486 2563.050711 2301.030581 1940.098688 2268.100034 1757.694099 2348.439939 2614.916537 0.989759332 0.874037248 0.910620072 0.980165399 0.879963298 0.741935224 0.867369953 0.672179809 0.898093651 1 11.35254918 -2.59650421 0.274492093 1.009651709 1.67E-16 0.592889526 0.063859875 7.20313485 0.197192702 0.025279264 2.927996703 0.002532187 2.59650421 -1.009651709 TNST(ph)GGSSGSSVGGGSGK ddPTM_HeLa_Curcumin_4h_R1 1 TNSTGGSSGSSVGGGSGK 18 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-5;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 0 TNS(0.009)T(0.973)GGS(0.017)SGSSVGGGSGK 294.52 3.48E-81 207520000 4540.4 5168 5630.3 3985.3 3971.2 2999.6 2335.5 1408.3 3036.3 3737.3 TRUE FALSE FALSE 4181.022549 5614.698892 5838.963871 3968.809885 3923.846034 2377.449148 2401.027844 1837.684187 2703.225486 3867.170897 1.081157947 1.451887967 1.509879968 1.026282518 1.014655452 0.614777369 0.620874512 0.475201184 0.699018884 1 11.91706281 -5.28400688 2.278680953 1.111899013 0.54641754 0.569549823 0.218012315 0.167284338 1.679672672 0.029949188 0.086871308 5.20E-06 5.28400688 -0.565481473 TNSTFNQVVLK ddPTM_HeLa_Curcumin_4h_R1 2 TNSTFNQVVLK 11 0 F8VYV2;A0A075B7A0;G3V203;H0YHA7;J3QQ67;Q07020-2;Q07020 F8VYV2 RPL18 60S ribosomal protein L18 0 0 ; ; 152.7 3.44E-07 3361200 940.84 781.94 1030.44 870.59 990.41 1630.32 967.71 843 960.12 1038.23 FALSE FALSE TRUE 866.3715212 849.5274093 1068.629013 866.9877293 978.6000076 1292.173255 994.8613381 1100.026819 854.7972381 1074.308415 0.806445811 0.790766783 0.994713434 0.807019397 0.910911609 1.202795432 0.926048166 1.023939498 0.795672105 1 10.06919251 -5.485155987 24.93476823 0.89593868 1.041508757 0.393420187 0.098624822 532.845384 352210.6835 0.014923131 0.033361213 3.27E-06 5.485155987 0.145570077 TNSTGGS(ph)SGSSVGGGSGK ddPTM_HeLa_Curcumin_4h_R1 1 TNSTGGSSGSSVGGGSGK 18 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-5;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 0 T(0.001)NS(0.039)T(0.353)GGS(0.601)S(0.007)GSSVGGGSGK 245.22 3.55E-32 95232000 10319 11666 10871 8717.4 9345.6 7188 5847 3730.6 7447.5 8725.8 TRUE FALSE FALSE 9502.240261 12674.35706 11273.88882 8681.329709 9234.159824 5697.127775 6011.051084 4868.042766 6630.527883 9029.020901 1.052410928 1.403735488 1.248628057 0.961491817 1.022719952 0.630979575 0.665747831 0.539155111 0.734357352 1 13.14035384 -5.281113745 2.639212826 1.071058574 0.600083234 0.599502571 0.168096596 0.128982883 1.764635964 0.021247391 0.058503276 5.23E-06 5.281113745 -0.47097534 TNT(ph)PQGVLPSSQLK ddPTM_HeLa_Curcumin_4h_R1 2 TNTPQGVLPSSQLK 14 0 Q14004-2;Q14004;A0A2R8Y7W5;A0A2R8Y4Z0;A0A2R8YF61 Q14004-2 CDK13 Cyclin-dependent kinase 13 1 0 T(0.001)NT(0.997)PQGVLPS(0.001)SQLK;T(0.047)NT(0.953)PQGVLPSSQLK ; 159.14 0.00092271 35041000 4996.4 4499.3 4915.7 4780.2 5329 4568.5 4343.9 1865.37 5546.4 3364 TRUE FALSE FALSE 4600.929668 4888.199444 5097.880166 4760.420799 5265.455155 3620.941602 4465.778143 2434.112726 4937.973796 3480.89875 1.321764866 1.404292338 1.464529862 1.367583817 1.512671162 1.040231809 1.282938248 0.699277084 1.41859162 1 11.76524414 -4.257803842 23.92602811 1.229963643 0.699276706 0.464120392 0.178877169 164.5917722 1083112.413 0.028665656 0.281150291 5.52E-05 4.257803842 -0.530686936 TNYNDRYDEIR ddPTM_HeLa_Curcumin_4h_R1 3 TNYNDRYDEIR 11 1 P62424;Q5T8U2 P62424 RPL7A 60S ribosomal protein L7a 0 0 ;; ;; 112.94 0.0048556 53010900 11093.5 10556 10614.2 11342.3 10791.2 12395 10412.4 9950.2 11733 11157.6 FALSE FALSE TRUE 10215.43777 11468.4136 11007.57159 11295.36857 10662.52199 9824.13728 10704.54392 12983.97017 10445.91925 11545.32577 0.884811566 0.993338242 0.953422347 0.978349922 0.923535827 0.850919019 0.927175563 1.124608386 0.904774752 1 13.49502126 -4.258572797 24.24389107 0.94177327 1.124608489 0.603829325 0.045756498 112.3753739 950326.2402 0.00743638 0.068932777 5.51E-05 4.258572797 0.182835219 TNYNDRYDEIRR ddPTM_HeLa_Curcumin_4h_R1 1 TNYNDRYDEIRR 12 2 P62424;Q5T8U2 P62424 RPL7A 60S ribosomal protein L7a 0 0 80.102 0.0094707 41678000 4127.9 2952.8 3283.6 3086 3076.2 3691.2 2690.3 3203.5 3704.4 2903.4 FALSE FALSE TRUE 3801.172359 3208.026875 3405.293105 3073.23095 3039.518324 2925.603512 2765.782577 4180.232403 3298.036588 3004.292934 1.265246913 1.067814273 1.133475723 1.022946503 1.011725019 0.973807673 0.920610153 1.39141971 1.097774638 1 11.55280977 -6.269223136 23.30354692 1.123775655 1.048203889 0.022091383 0.134468233 590.5307645 1767972.223 0.02257738 0.034932085 5.38E-07 6.269223136 -0.075571766 S(ph)IADSEESEAYK ddPTM_HeLa_Curcumin_4h_R1 1 SIADSEESEAYK 12 0 A0A0A0MQR2;Q9BY42 A0A0A0MQR2 RTFDC1 Protein RTF2 homolog 1 0 S(0.999)IADS(0.001)EESEAYK 139.78 0.00070335 0 1902.9 1457 1760 2002.2 2005.3 2190.3 2323.8 2734.9 2275.2 1604.7 TRUE FALSE FALSE 1752.283457 1582.936588 1825.227148 1993.915427 1981.388107 1736.00709 2388.999574 3568.75842 2025.616252 1660.463206 1.055297974 0.953310246 1.099227699 1.200818796 1.193274323 1.045495669 1.4387549 2.149254743 1.219910351 1 10.69737004 -1.340410606 0.843263079 1.036902865 200 0.910029612 0.099560345 51.92643843 0.269956164 0.013379752 19638.669 0.045665624 1.340410606 198.9630971 up S(ph)APTTLYLVHTDHAYQATPPVTIPGSAK ddPTM_HeLa_Curcumin_4h_R1 1 SAPTTLYLVHTDHAYQATPPVTIPGSAK 28 0 Q6ZNC4 Q6ZNC4 ZNF704 Zinc finger protein 704 1 0 S(0.657)APT(0.109)T(0.109)LY(0.084)LVHT(0.037)DHAY(0.003)QATPPVTIPGSAK 60.562 0.0011901 17640000 1834 1266.5 1469.5 1609.5 1622.5 2122.4 1218.5 603.51 2063.1 1827.8 TRUE FALSE FALSE 1688.836965 1375.970617 1523.960963 1602.840315 1603.152747 1682.190316 1252.687831 787.5174208 1836.783092 1891.315914 0.89294282 0.727520245 0.805767535 0.847473605 0.847638798 0.889428521 0.662336642 0.416385975 0.97116673 1 10.88517465 -4.06528706 0.969598537 0.912986062 2.39E-142 0.747965968 0.081180984 1.103769167 0.616985748 0.015102329 1.14815644 8.60E-05 4.06528706 -0.912986062 down KETSFGSS(ph)ENITMTSLSK ddPTM_HeLa_Curcumin_4h_R1 1 KETSFGSSENITMTSLSK 18 1 Q9UMZ2-6;Q9UMZ2-9;Q9UMZ2-4;Q9UMZ2-8;Q9UMZ2-3;Q9UMZ2-7;Q9UMZ2-5;Q9UMZ2 Q9UMZ2-6 SYNRG Synergin gamma 1 0 KET(0.024)S(0.024)FGS(0.406)S(0.546)ENITMTSLSK 65.197 0.0091019 22777000 2327.6 1512.8 1983 2040.5 1705.8 1991 1633.2 581.73 1951.9 1579.4 TRUE FALSE FALSE 2143.368004 1643.559691 2056.491724 2032.056952 1685.459449 1578.044157 1679.023196 759.096799 1737.781453 1634.284032 1.311502751 1.005675671 1.258344133 1.243392771 1.031313661 0.965587453 1.027375391 0.464482785 1.063328907 1 10.67444302 -4.06483266 1.234316904 1.145204616 1.05E-26 0.725905736 0.117416286 1.023925106 0.953583206 0.020569337 1.667839695 8.61E-05 4.06483266 -1.145204616 down TPADTGFAFPDWAYKPESS(ph)PGSR ddPTM_HeLa_Curcumin_4h_R1 2 TPADTGFAFPDWAYKPESSPGSR 23 1 P50548 P50548 ERF ETS domain-containing transcription factor ERF 1 0 TPADTGFAFPDWAYKPES(0.401)S(0.432)PGS(0.167)R;TPADTGFAFPDWAYKPES(0.242)S(0.737)PGS(0.021)R ; 123.68 2.00E-06 195454000 1827.53 1532.08 1486.19 1550.42 2215.6 3026 2478.2 1706.11 1992.62 2049.41 TRUE FALSE FALSE 1682.879072 1664.506168 1541.269509 1544.004773 2189.180417 2398.37349 2547.731622 2226.295085 1774.034571 2120.626845 0.793576237 0.784912335 0.726799018 0.728088856 1.032327032 1.130973842 1.201404966 1.049828776 0.836561404 1 11.05027506 -5.559143381 5.889408587 0.864913679 1.127256441 0.708070889 0.089470303 0.109651452 10.25858714 0.017248998 0.035295259 2.76E-06 5.559143381 0.262342762 TPAPEPEPCEASELPAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 TPAPEPEPCEASELPAKR 18 1 H0Y5D5;A0A494C0L7;Q9BTG3;Q5SYW2;F5H2X7;Q9ULV3-5;Q9ULV3-3;Q9ULV3-4;Q9ULV3-2;Q9ULV3 H0Y5D5 CIZ1 Cip1-interacting zinc finger protein 0 1 TPAPEPEPCEASELPAK(1)R 84.566 0.0065747 3116100 140.49 160.62 232.04 260.36 262.34 204.69 129.32 159.23 287.82 180.7 FALSE TRUE FALSE 129.3700683 174.5032771 240.6396065 259.2826993 259.2117668 162.2349867 132.9483712 207.778494 256.2468661 186.9793115 0.691895094 0.933275856 1.286985199 1.386691913 1.386312553 0.867662766 0.71103252 1.111237881 1.370455715 1 7.546734841 -6.966349404 10.69087838 0.852300173 1.117722012 0 0.2677939 0.623966446 194.3120251 0.039936338 0.05244759 1.08E-07 6.966349404 0.265421839 TPAQFDADELR ddPTM_HeLa_Curcumin_4h_R1 3 TPAQFDADELR 11 0 P04083;Q5T3N1 P04083 ANXA1 Annexin A1;Annexin 0 0 ;; ;; 181.4 7.04E-07 86408000 5896.9 4259.8 4744.7 4361.3 4900.8 7040.9 5068.1 5084.5 5318.6 4939 FALSE FALSE TRUE 5430.154143 4627.998131 4920.542756 4343.254096 4842.361161 5580.537973 5210.297246 6634.740644 4735.162886 5110.629882 1.062521503 0.905563157 0.962805538 0.849847122 0.947507699 1.091947197 1.019501973 1.298223663 0.926532149 1 12.3192854 -3.614274513 1.416973951 0.999847298 2.353970892 0.624144391 0.073124223 3.816661102 1.814372618 0.011400588 11.56571183 0.000243067 3.614274513 1.354123593 TPAQYDASELK ddPTM_HeLa_Curcumin_4h_R1 1 TPAQYDASELK 11 0 H0YMW4;P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YNP5;H0YKS4;H0YMM1;H0YKX9;H0YMT9;H0YLV6;H0YKZ7;P07355-2 H0YMW4;P07355;P07355-2 ANXA2;ANXA2P2 Annexin;Annexin A2;Putative annexin A2-like protein 0 0 163.46 4.55E-08 32044000 4566.1 2847.6 3281.4 3680.7 3722.6 5609.7 4322.1 4390.3 4288.3 2921.2 FALSE FALSE TRUE 4204.688367 3093.733855 3403.011571 3665.470239 3678.210426 4446.184986 4443.366494 5728.88226 3817.884219 3022.711483 1.391031989 1.023496246 1.12581422 1.212643105 1.216857926 1.470926025 1.469993587 1.89527922 1.263066039 1 11.56162757 -1.000000277 0.539869293 1.162632751 31.8411187 0.79130991 0.114933586 49.53897268 0.426368432 0.028717047 1763.476665 0.099999936 1.000000277 30.67848595 TPAS(ph)PHFR ddPTM_HeLa_Curcumin_4h_R1 2 TPASPHFR 8 0 P29590-2 P29590-2 PML Protein PML 1 0 TPAS(1)PHFR;TPAS(1)PHFR ; 112.13 0.005043 34396000 3254.8 2484.6 2300.1 2908.7 2892.2 3185.8 2050.6 1679.02 3132.1 2574.5 TRUE FALSE FALSE 2997.179146 2699.357753 2385.343729 2896.66457 2857.712404 2525.029169 2108.134317 2190.945469 2788.516466 2663.963683 1.125082584 1.013286243 0.895411504 1.087351374 1.07272949 0.947846693 0.791352499 0.82243819 1.046754685 1 11.3793587 -4.945610258 3.129338512 1.046868219 0.805931987 0.690497791 0.059850874 0.112848287 2.232305791 0.010033433 0.03457247 1.13E-05 4.945610258 -0.240936232 TPAS(ph)TPVSGTPQAS(ph)PMIER ddPTM_HeLa_Curcumin_4h_R1 1 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2 0 T(0.149)PAS(0.831)T(0.017)PVS(0.003)GT(0.005)PQAS(0.996)PMIER 136.67 0.00047541 92710000 2064.6 1806.1 1992.5 1857.7 2012 1767.8 1391.6 955.01 2086.1 1372.6 TRUE FALSE FALSE 1901.184731 1962.211236 2066.343803 1850.01333 1988.008214 1401.138353 1430.644551 1246.188153 1857.260049 1420.297748 1.338581811 1.381549213 1.454866633 1.302553167 1.399712291 0.986510297 1.007284953 0.877413313 1.307655421 1 10.47197769 -5.130403195 7.018061603 1.227704717 0.955957925 0.531624506 0.137826986 0.241430072 12.67501282 0.026389568 0.067995905 7.41E-06 5.130403195 -0.271746793 TPASTPVS(ph)GTPQAS(ph)PMIER ddPTM_HeLa_Curcumin_4h_R1 2 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2 0 TPAS(0.001)T(0.018)PVS(0.491)GT(0.491)PQAS(0.998)PMIER;TPAST(0.001)PVS(0.564)GT(0.439)PQAS(0.996)PMIER ; 111.93 0.00050934 10771000 3011.92 2655.19 2661.24 2715.66 2564.6 1907.39 1671.07 704.9 2555.61 2296.17 TRUE FALSE FALSE 2773.523354 2884.692792 2759.867895 2704.423318 2534.01882 1511.775813 1717.955727 919.820765 2275.265977 2375.961737 1.167326608 1.214115845 1.161579268 1.138243633 1.066523413 0.636279528 0.723056984 0.387136186 0.957618947 1 11.21429589 -5.20799521 2.455797933 1.104599643 0.559971387 0.836911127 0.105296345 0.086979974 1.017166502 0.015476894 0.046385031 6.19E-06 5.20799521 -0.544628256 TPASTPVSGT(ph)PQAS(ph)PMIER ddPTM_HeLa_Curcumin_4h_R1 1 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2 0 TPAS(0.003)T(0.01)PVS(0.325)GT(0.671)PQAS(0.993)PMIER 88.092 0.01879 8853900 1683.7 1703.9 1673.4 1690.2 2125.8 1719 1303 783.12 1853.9 1821.5 TRUE FALSE FALSE 1550.433368 1851.177524 1735.417676 1683.2064 2100.451223 1362.460023 1339.558673 1021.889683 1650.531808 1884.796989 0.822599663 0.982162819 0.920745144 0.893043871 1.114417752 0.722868314 0.710717749 0.542174934 0.875708003 1 10.88019342 -5.061808781 5.977306973 0.929669006 0.646328965 0.705944563 0.085354965 0.098670264 7.174315352 0.013197862 0.034806189 8.67E-06 5.061808781 -0.283340041 TPASTPVSGT(ph)PQASPMIER ddPTM_HeLa_Curcumin_4h_R1 3 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 0 T(0.071)PAS(0.014)T(0.018)PVS(0.055)GT(0.842)PQASPMIER;T(0.006)PAS(0.01)T(0.001)PVS(0.045)GT(0.645)PQAS(0.292)PMIER;TPAST(0.001)PVS(0.364)GT(0.628)PQAS(0.007)PMIER ;; 137.52 0.0054462 51066300 3081.71 2114.21 2584.89 2236.07 2758.31 3703.23 2303.99 1679.78 3086.11 2020.89 TRUE FALSE FALSE 2837.789402 2296.952892 2680.688297 2226.817735 2725.418955 2935.138354 2368.633759 2191.937189 2747.571454 2091.115777 1.357069481 1.098434107 1.281941596 1.064894521 1.303332405 1.403623073 1.132712872 1.04821417 1.313926031 1 11.03005723 -9.566374106 1.34168417 0.999951509 1.230703976 0 0.152778874 0.412992335 1.332044586 0.085990837 0.020182896 2.71E-10 9.566374106 0.230752467 TPASTPVSGTPQAS(ph)PMIER ddPTM_HeLa_Curcumin_4h_R1 1 TPASTPVSGTPQASPMIER 19 0 Q9UHR4 Q9UHR4 BAIAP2L1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 1 0 TPASTPVS(0.029)GT(0.005)PQAS(0.966)PMIER 181.64 2.62E-07 62738000 1836.6 1522.5 1359.9 1212.8 1715.5 1583.5 1174.7 1128.2 1506.7 1121.8 TRUE FALSE FALSE 1691.231172 1654.098116 1410.29909 1207.781755 1695.043783 1255.06425 1207.65892 1472.182986 1341.41878 1160.782467 1.456975119 1.424985442 1.214955542 1.040489316 1.460259637 1.081222612 1.040383496 1.268267767 1.15561599 1 10.18088192 TPAT(ph)TPEAR ddPTM_HeLa_Curcumin_4h_R1 1 TPATTPEAR 9 0 H0Y7U4;A0A0C4DG98;Q8NI27-2;Q8NI27;H7C477 H0Y7U4 THOC2 THO complex subunit 2 1 0 T(0.014)PAT(0.493)T(0.493)PEAR 118.03 0.019552 15369000 5272.5 5219.9 5480.4 4963.9 6075.2 6262.2 4637.8 3168.9 5547.7 4676.1 TRUE FALSE FALSE 4855.176061 5671.084897 5683.508445 4943.360697 6002.757208 4963.34913 4767.924186 4135.083022 4939.13119 4838.594127 1.003427015 1.172052201 1.174619796 1.021652275 1.240599449 1.025783316 0.98539453 0.854604233 1.020778156 1 12.24037221 -4.343313698 2.359201012 1.045658378 0.828468918 0.344828862 0.087185874 0.502173408 3.768912099 0.013752599 0.20579524 4.54E-05 4.343313698 -0.21718946 TPAVEGLTEAEEEELRAELTK ddPTM_HeLa_Curcumin_4h_R1 1 TPAVEGLTEAEEEELRAELTK 21 1 O43399;O43399-5;O43399-7;A0A087WYR3;O43399-2;O43399-4;O43399-3;A0A087WZ51;O43399-6 O43399 TPD52L2 Tumor protein D54 0 0 65.808 0.0039054 2200400 759.11 422.44 623.07 553.74 935.72 770.63 515.56 606.14 674.33 510.07 FALSE FALSE TRUE 699.0256425 458.9538312 646.1615223 551.4487706 924.5621501 610.7926512 530.025226 790.9492957 600.3576861 527.7948945 1.324426685 0.869568531 1.224266337 1.044816417 1.751745157 1.157253807 1.004225754 1.498592169 1.137482936 1 9.043833585 TPCNAGTFSQPEK ddPTM_HeLa_Curcumin_4h_R1 2 TPCNAGTFSQPEK 13 0 O43684-2;O43684;J3QT28;J3QSX4 O43684-2 BUB3 Mitotic checkpoint protein BUB3 0 0 ; ; 169.09 7.36E-06 3599900 1244.28 1019.49 1213.44 1145.4 1122.25 1328.77 1215.29 883.24 1364.06 1615.59 FALSE FALSE TRUE 1145.793925 1107.610173 1258.411154 1140.660638 1108.867902 1053.168124 1249.387767 1152.53581 1214.426031 1671.731632 0.685393458 0.66255262 0.752759073 0.682322818 0.663304971 0.629986359 0.747361444 0.689426334 0.726447958 1 10.70712755 -9.185025001 0.650120859 1.032805024 0.684404247 0.150591104 0.091365404 0.204582627 0.134806726 0.040552245 0.00824623 6.53E-10 9.185025001 -0.348400777 TPDGNKS(ph)PAPKPSDLRPGDVSSK ddPTM_HeLa_Curcumin_4h_R1 1 TPDGNKSPAPKPSDLRPGDVSSK 23 3 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 1 0 T(0.208)PDGNKS(0.79)PAPKPS(0.002)DLRPGDVSSK 46.415 0.011695 101470000 6113.6 4985.2 5758.7 5802.6 6321.3 5886.2 4895.4 5511.3 4709.5 4562.6 TRUE FALSE FALSE 5629.702109 5416.098474 5972.122488 5778.590379 6245.922626 4665.335769 5032.751749 7191.669999 4192.879633 4721.15001 1.192442963 1.14719898 1.264971982 1.223979405 1.322966356 0.988177829 1.066001236 1.523287755 0.888105572 1 12.20492261 -9.197353855 0.479063177 0.953493772 1.216943576 0.361333251 0.141323869 1.802883562 0.579519505 0.227177918 0.037716877 6.35E-10 9.197353855 0.263449804 TPDTIRR ddPTM_HeLa_Curcumin_4h_R1 1 TPDTIRR 7 1 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 116.9 0.020003 1343100 435.37 522.49 477 298.73 296.75 576.43 380.45 247.27 471.32 566.03 FALSE FALSE TRUE 400.9100051 567.6517074 494.6780396 297.4939344 293.2114501 456.8719203 391.1244031 322.6614847 419.6173752 585.6995004 0.684497775 0.969185917 0.844593583 0.507929295 0.500617552 0.780044921 0.667790228 0.550899368 0.716437994 1 9.194016854 -6.283567904 19.58963176 0.857534003 0.609461128 0.506202463 0.118686993 37.57228663 33261.35854 0.021896154 0.033495203 5.21E-07 6.283567904 -0.248072875 TPEAS(ph)PEPK ddPTM_HeLa_Curcumin_4h_R1 1 TPEASPEPK 9 0 A0A087WW66;Q99460-2;Q99460 A0A087WW66 PSMD1 26S proteasome non-ATPase regulatory subunit 1 1 0 T(0.246)PEAS(0.754)PEPK 119.27 0.0064232 18862000 3567.8 2709.5 3094.8 3259 2900.7 2827.6 2461.9 2341.5 3174.2 2696.6 TRUE FALSE FALSE 3285.404865 2943.697107 3209.49601 3245.515122 2866.111047 2241.123886 2530.974288 3055.412571 2825.998201 2790.306649 1.177435056 1.054972617 1.150230571 1.163139228 1.027167049 0.803181932 0.907059548 1.095009601 1.012791265 1 11.44620796 -5.515973259 24.00411094 1.093887363 0.929430133 0.397703612 0.08701263 145.8749447 507072.8256 0.013733248 0.028372621 3.05E-06 5.515973259 -0.16445723 TPEDGDYS(ph)YEIIEK ddPTM_HeLa_Curcumin_4h_R1 3 TPEDGDYSYEIIEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 TPEDGDYS(1)YEIIEK;TPEDGDYS(1)YEIIEK;T(0.008)PEDGDYS(0.992)YEIIEK ;; 224.67 4.37E-15 64043800 5524.4 4404.4 4459.3 5219.9 4973.4 6868.7 4825.4 2351.71 5162 4347 TRUE FALSE FALSE 5087.137911 4785.09671 4624.565581 5198.301437 4914.095453 5444.054194 4960.787737 3068.735553 4595.741515 4498.057926 1.130963183 1.063813937 1.02812495 1.155676855 1.092492701 1.210312158 1.102873244 0.682235668 1.021716836 1 12.13508653 -4.259522226 24.72254568 1.081127327 0.682235509 0.794091116 0.062090484 56.1587262 724124.3873 0.009809201 0.085186414 5.50E-05 4.259522226 -0.398891818 TPEDGDYSYEIIEK ddPTM_HeLa_Curcumin_4h_R1 1 TPEDGDYSYEIIEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 0 0 155.86 0.0032769 7186300 1146.7 782.05 857.57 1001.4 898.51 1190.6 947.18 915.57 1072.2 782.31 FALSE FALSE TRUE 1055.937485 849.6469173 889.3522986 997.2564721 887.7958551 943.6561392 973.7553216 1194.723078 954.5823425 809.4952143 1.304439441 1.049600915 1.098650471 1.231948571 1.096727738 1.165734056 1.202916712 1.475886524 1.179231607 1 9.660878741 -9.535564222 1.259808088 0.998560737 1.204451648 0.045979337 0.127132075 0.474723636 1.333990614 0.084886985 0.019647818 2.91E-10 9.535564222 0.205890911 TPEEGGYSYDISEKTT(ph)SPPEVSGYSYEK ddPTM_HeLa_Curcumin_4h_R1 1 TPEEGGYSYDISEKTTSPPEVSGYSYEK 28 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 TPEEGGYSYDIS(0.004)EKT(0.187)T(0.791)S(0.018)PPEVSGYSYEK 99.378 7.39E-06 0 1053 552.35 390.6 776.17 497.4 1016.9 905.71 650.46 1506.2 1156.6 TRUE FALSE FALSE 969.6539389 600.0926728 405.0759796 772.9584142 491.4688299 805.9834772 931.121785 848.7822597 1340.973628 1196.791764 0.810211073 0.501417783 0.338468221 0.645858735 0.410655257 0.673453396 0.778014867 0.709214656 1.120473644 1 10.22495644 -7.576247256 2.073494549 0.932080786 0.579338329 0.607413597 0.145950792 0.166376424 1.460995954 0.02836408 0.029914251 2.65E-08 7.576247256 -0.352742456 TPEELDDS(ph)DFETEDFDVR ddPTM_HeLa_Curcumin_4h_R1 10 TPEELDDSDFETEDFDVR 18 0 G3XAM7;P35221-3;P35221;P35221-2 G3XAM7 CTNNA1 Catenin alpha-1 1 0 TPEELDDS(1)DFETEDFDVR;TPEELDDS(1)DFETEDFDVR;TPEELDDS(1)DFETEDFDVR;T(0.005)PEELDDS(0.995)DFETEDFDVR;TPEELDDS(1)DFETEDFDVR;TPEELDDS(1)DFETEDFDVR;TPEELDDS(1)DFETEDFDVR;T(0.002)PEELDDS(0.998)DFETEDFDVR;TPEELDDS(1)DFETEDFDVR;TPEELDDS(1)DFETEDFDVR ;;;;;;;;; 237.06 7.88E-57 1735593600 12249.64 10687.76 10830.15 12796.89 11664.97 14033.08 9310.33 10705.59 13970.66 11610.39 TRUE FALSE FALSE 11280.06807 11611.56235 11231.52489 12743.93986 11525.87285 11122.46102 9571.552802 13969.67511 12438.11355 12013.85019 0.938921985 0.966514662 0.934881384 1.060770666 0.959382102 0.925803206 0.796709852 1.162797512 1.035314521 1 13.55241096 -9.546228199 1.318989499 0.999952692 0.959760494 0.030391343 0.090369067 1.608949126 5.023987431 0.057364104 0.01367719 2.84E-10 9.546228199 -0.040192198 TPEELDDSDFETEDFDVRS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 TPEELDDSDFETEDFDVRSR 20 1 G3XAM7;P35221-3;P35221;P35221-2 G3XAM7 CTNNA1 Catenin alpha-1 1 0 TPEELDDSDFETEDFDVRS(1)R;TPEELDDSDFETEDFDVRS(1)R ; 69.649 0.0029102 5947500 1286.55 1208.52 803.84 1087.25 983.2 1555.91 889.44 886 1383.69 1229.28 TRUE FALSE FALSE 1184.71821 1312.979084 833.6310175 1082.751248 971.4759821 1233.196727 914.3952926 1156.137321 1231.902669 1271.997389 0.931384153 1.03221838 0.655371642 0.851221282 0.763740548 0.969496273 0.7188657 0.908914855 0.968478929 1 10.31287999 -6.786677899 24.99936932 0.971539253 0.813916032 0.475630299 0.087990913 146.8984284 145505.9668 0.01310662 0.017229201 1.63E-07 6.786677899 -0.157623221 TPFNTDLGENS(ph)GIGK ddPTM_HeLa_Curcumin_4h_R1 1 TPFNTDLGENSGIGK 15 0 Q6P0N0 Q6P0N0 MIS18BP1 Mis18-binding protein 1 1 0 TPFNT(0.004)DLGENS(0.996)GIGK 163.91 0.00025991 5317600 2062.9 1795.2 1658.2 1905.7 1919.5 2313.9 2574.7 838.67 1925.6 1752.2 TRUE FALSE FALSE 1899.619288 1950.369089 1719.654351 1897.814718 1896.611216 1833.971057 2646.939153 1094.376622 1714.366498 1813.08882 1.047725444 1.075716241 0.94846669 1.046730142 1.046066357 1.011517493 1.459905948 0.60359791 0.945550201 1 10.82423389 -5.61361399 2.355094057 1.022694157 1.064063236 0 0.196788115 1.758588334 19.66977169 0.02586387 0.059519379 2.43E-06 5.61361399 0.041369078 TPGDFSYAYQKPEET(ph)TRSPDEEDYDYESYEK ddPTM_HeLa_Curcumin_4h_R1 4 TPGDFSYAYQKPEETTRSPDEEDYDYESYEK 31 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 TPGDFS(0.001)Y(0.002)AY(0.002)QKPEET(0.407)T(0.119)RS(0.407)PDEEDY(0.056)DY(0.004)ESYEK;T(0.008)PGDFS(0.028)Y(0.099)AY(0.083)QKPEET(0.542)T(0.119)RS(0.119)PDEEDY(0.001)DYESYEK;T(0.003)PGDFS(0.018)Y(0.047)AY(0.125)QKPEET(0.521)T(0.143)RS(0.143)PDEEDYDYESYEK;T(0.002)PGDFS(0.017)Y(0.039)AY(0.102)QKPEET(0.362)T(0.116)RS(0.362)PDEEDY(0.001)DYESYEK ;;; 66.432 6.30E-05 548978000 7120.2 5342.8 6331.5 6340.8 6643.9 8300.6 6384.02 8344.9 6446.4 6721.8 TRUE FALSE FALSE 6556.628657 5804.607825 6566.15096 6314.56345 6564.675832 6578.961993 6563.138419 10889.22159 5739.246048 6955.38205 0.942669807 0.834549099 0.944038863 0.907867232 0.943826778 0.94588075 0.943605739 1.565582094 0.825151804 1 12.76391405 -4.260979048 24.95960813 0.951725405 1.565582284 0.914194908 0.058573634 6.552670917 355178.1383 0.00695626 0.055065265 5.48E-05 4.260979048 0.613856879 TPGNGDGGS(ph)TSETPQPPR ddPTM_HeLa_Curcumin_4h_R1 1 TPGNGDGGSTSETPQPPR 18 0 H0YMJ0;B3KTM8;Q9UBU8-2;H0YNE0;H0YLJ3;Q9UBU8;H0YNI8;H0YNX3;H0YLV1;H0YMT8;H0YM21;Q9UBU8-3 H0YMJ0 MORF4L1 Mortality factor 4-like protein 1 1 0 T(0.019)PGNGDGGS(0.368)T(0.368)S(0.199)ET(0.046)PQPPR 142.97 0.00024696 5315200 768.6 773.07 775.78 964.05 1029.5 1258.8 1054.9 504.51 1022.6 776.84 TRUE FALSE FALSE 707.764499 839.8907261 804.5310892 960.0610165 1017.223885 997.7106904 1084.497655 658.3327765 910.4233384 803.8351322 0.880484655 1.044854464 1.000865796 1.194350655 1.265463332 1.241188212 1.349154337 0.818989803 1.132599587 1 9.650755823 -6.426887964 2.114906058 0.948458182 1.19398929 0.170025051 0.149380555 0.233279557 2.054317323 0.021311128 0.034551021 3.74E-07 6.426887964 0.245531108 TPGRPAQWPPWDPGACS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 TPGRPAQWPPWDPGACSR 18 1 J3QQL7 J3QQL7 SMARCD2 1 0 TPGRPAQWPPWDPGACS(1)R 83.966 0.0021867 20600000 1766.8 1424.5 1497.9 1507.8 1299.8 1843.1 1169.4 1175 1326 1401.2 TRUE FALSE FALSE 1626.955916 1547.627433 1553.413492 1501.561123 1284.300734 1460.820284 1202.210217 1533.252091 1180.541117 1449.891596 1.122122454 1.067409065 1.071399749 1.035636821 0.885790867 1.00753759 0.829172485 1.057494295 0.814227161 1 10.50172932 -5.901904264 6.12895951 1.06063863 0.941689532 0.026723817 0.100962356 0.159126129 8.450788763 0.00992685 0.018146957 1.25E-06 5.901904264 -0.118949099 TPGT(ph)PGTPSYPR ddPTM_HeLa_Curcumin_4h_R1 1 TPGTPGTPSYPR 12 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 TPGT(0.999)PGT(0.001)PSYPR 171.26 0.00038533 59572000 1974.1 1357.7 1511.8 1890.3 1976.6 1833.8 1691.9 764.24 2144.2 1932.5 TRUE FALSE FALSE 1817.847902 1475.053538 1567.828638 1882.478439 1953.030336 1453.449209 1739.37016 997.2532579 1908.986625 1999.654231 0.909081117 0.737654298 0.784049869 0.941401973 0.976684021 0.726850265 0.869835461 0.498712849 0.954658358 1 10.96553484 -2.437358068 0.223562417 0.984930443 4.80E-40 0.427559295 0.111263278 19.43566711 0.409240933 0.086633917 6.124522321 0.003652935 2.437358068 -0.984930443 TPHDILEDINAS(ph)PEMR ddPTM_HeLa_Curcumin_4h_R1 3 TPHDILEDINASPEMR 16 0 Q9Y6Q9-2;Q9Y6Q9-3;Q9Y6Q9-5;Q9Y6Q9;Q9Y6Q9-4 Q9Y6Q9-2 NCOA3 Nuclear receptor coactivator 3 1 0 TPHDILEDINAS(1)PEMR;TPHDILEDINAS(1)PEMR;TPHDILEDINAS(1)PEMR ;; 167.97 7.73E-05 56132000 3940.76 3536.08 3755.5 4305.58 3815.11 4282.57 2795.14 2535.34 4349.46 3141.04 TRUE FALSE FALSE 3628.844688 3841.722999 3894.682134 4287.764651 3769.617305 3394.316707 2873.564106 3308.353495 3872.33512 3250.190906 1.116502012 1.181999184 1.198293345 1.319234708 1.15981412 1.044343796 0.884121637 1.01789513 1.191417745 1 11.66630874 -4.969327642 6.499389029 1.10337108 0.952568326 0.347223099 0.096212729 0.20061862 26.58686551 0.016064089 0.048269592 1.07E-05 4.969327642 -0.150802754 TPHPVLT(ph)PVAANQAK ddPTM_HeLa_Curcumin_4h_R1 3 TPHPVLTPVAANQAK 15 0 A0A494C1F2;P35658-2;P35658;P35658-5;P35658-4;P35658-3;A0A0A0MSW3;A0A494C104;H0Y837 A0A494C1F2 NUP214 Nuclear pore complex protein Nup214 1 0 TPHPVLT(1)PVAANQAK;TPHPVLT(1)PVAANQAK;TPHPVLT(1)PVAANQAK ;; 138.97 0.00052745 45802700 8630.51 6494.06 6586.19 7431.14 7811.42 14105.3 12495.26 5352.98 8794.89 5797.11 TRUE FALSE FALSE 7947.396027 7055.377609 6830.279995 7400.391912 7718.273918 11179.70178 12845.84337 6985.07896 7830.112571 5998.559141 1.324884166 1.17617872 1.138653439 1.233694915 1.286687976 1.863731192 2.141488158 1.164459464 1.305332228 1 12.55040029 -5.373887689 4.131650461 1.16577888 1.763263803 0.480063551 0.243515012 0.128939756 3.751590079 0.03422662 0.079947688 4.23E-06 5.373887689 0.597484923 TPHVQAVQGPLGS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 2 TPHVQAVQGPLGSPPK 16 0 Q15149 Q15149 PLEC Plectin 1 0 TPHVQAVQGPLGS(1)PPK;TPHVQAVQGPLGS(1)PPK ; 144.5 0.00017744 588750000 8045.5 7405 8080.4 7707.3 8323.2 9220.1 7127.9 6373.2 7758.2 7523.3 TRUE FALSE FALSE 7408.690185 8045.055204 8379.866732 7675.409235 8223.951276 7307.747328 7327.88969 8316.359341 6907.14487 7784.734115 0.951694698 1.033439946 1.076448676 0.985956504 1.056420316 0.938727928 0.941315346 1.068290737 0.887267923 1 12.92643205 -3.494240278 4.151379151 0.988916193 11.10323353 0.16250954 0.055576911 1081.666011 121.6894736 0.006676749 102334.6719 0.00032045 3.494240278 10.11431733 TPITSVPLGPLASS(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 2 TPITSVPLGPLASSPTK 17 0 Q15911 Q15911 ZFHX3 Zinc finger homeobox protein 3 1 0 TPITSVPLGPLAS(0.228)S(0.769)PT(0.003)K;TPITSVPLGPLAS(0.042)S(0.941)PT(0.017)K ; 197.29 6.82E-08 119490000 6614 3872.2 5305.6 5581.2 5550.1 6583.8 5597.3 2754.6 6004.4 5268.7 TRUE FALSE FALSE 6090.494921 4206.895714 5502.230203 5558.106473 5483.918682 5218.245665 5754.345174 3594.464859 5345.732342 5451.786933 1.117155714 0.771654462 1.009252612 1.019501778 1.005893801 0.957162437 1.055497077 0.659318661 0.98054682 1 12.41251346 -4.258220458 24.86819969 1.022152576 0.659318516 0.530062285 0.089314075 161.4910494 1247554.593 0.013078196 0.125032999 5.52E-05 4.258220458 -0.36283406 TPKDESANQEEPEAR ddPTM_HeLa_Curcumin_4h_R1 1 TPKDESANQEEPEAR 15 1 P50552;K7EM16 P50552 VASP Vasodilator-stimulated phosphoprotein 0 0 85.163 0.011251 1003900 365.17 254.14 222.56 177.32 283.67 205.84 206.87 0 295.92 266.73 FALSE FALSE TRUE 336.2664092 276.1067292 230.8082694 176.5862968 280.2874205 163.1464637 212.6742154 0 263.4583164 275.9988476 1.218361642 1.000390877 0.836265337 0.639808095 1.015538372 0.591112844 0.770561969 0 0.954563103 1 8.108518433 -4.695458373 0.525304995 1.0921323 4.80E-16 0.630229545 0.195813233 1.286378983 0.315640212 0.040777075 0.78742904 2.02E-05 4.695458373 -1.0921323 TPLALAGS(ph)PTPK ddPTM_HeLa_Curcumin_4h_R1 1 TPLALAGSPTPK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 0 T(0.005)PLALAGS(0.873)PT(0.122)PK 127.79 0.0027559 102990000 2179.2 1793.5 1611.1 2136.3 1991.5 2163.4 1996.2 982.01 1735.9 1956.3 TRUE FALSE FALSE 2006.714021 1948.522148 1670.808783 2127.460557 1967.752663 1714.686453 2052.208 1281.420328 1545.476113 2024.281279 0.99132173 0.9625748 0.825383705 1.05097082 0.972074723 0.847059384 1.013795869 0.633024838 0.763469054 1 10.98319406 -3.875340769 2.095990422 0.976640521 1.10E-07 0.400098879 0.098314534 1.61833994 2.608945985 0.009804032 4.493837429 0.000133248 3.875340769 -0.97664041 TPLALAGSPT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 TPLALAGSPTPK 12 0 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785 B9EGQ5 WIZ Protein Wiz 1 0 T(0.001)PLALAGS(0.318)PT(0.681)PK 109.6 0.01652 88444000 2304.2 2208.1 2415 2630.9 2427 2959.5 2387.1 1507.6 2282.6 1880.1 TRUE FALSE FALSE 2121.820139 2398.958325 2504.502024 2620.014033 2398.05961 2345.66634 2454.075601 1967.2603 2032.204491 1945.433335 1.090667102 1.233122864 1.287374889 1.346750868 1.232660902 1.205729488 1.261454483 1.01121959 1.044602482 1 10.92587583 -7.462103185 1.960124808 1.03315304 1.234383845 0.497404417 0.083486545 0.180105647 1.351609228 0.016125699 0.01774939 3.45E-08 7.462103185 0.201230805 TPLGAS(ph)LDEQSSSTLK ddPTM_HeLa_Curcumin_4h_R1 4 TPLGASLDEQSSSTLK 16 0 E9PHV5;P28290-3;P28290 E9PHV5 SSFA2 Sperm-specific antigen 2 1 0 TPLGAS(1)LDEQSSSTLK;T(0.011)PLGAS(0.984)LDEQS(0.005)SSTLK;TPLGAS(0.999)LDEQS(0.001)SSTLK;T(0.011)PLGAS(0.987)LDEQS(0.002)SSTLK ;;; 224.67 1.98E-16 84742000 8085.6 3661.56 4913.4 4873.8 4879 15263.8 6099.8 1829.18 6852.2 3971.6 TRUE FALSE FALSE 7445.616228 3978.048931 5095.494926 4853.633507 4820.821112 12097.91582 6270.943971 2386.888561 6100.530803 4109.612804 1.811756139 0.967986309 1.239896596 1.181043991 1.173059687 2.943809161 1.525920876 0.580806192 1.484453912 1 12.00478676 -9.617820356 1.424173557 0.999708687 1.496525851 0 0.616083224 0.911320136 3.316118114 0.429396587 0.098213719 2.41E-10 9.617820356 0.496817164 TPLSFTNPLHS(ph)DDS(ph)DSDERNSDGAVTQNK ddPTM_HeLa_Curcumin_4h_R1 3 TPLSFTNPLHSDDSDSDERNSDGAVTQNK 29 1 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 2 0 T(0.001)PLS(0.001)FT(0.029)NPLHS(0.97)DDS(0.978)DS(0.02)DERNS(0.001)DGAVTQNK;T(0.001)PLS(0.002)FT(0.017)NPLHS(0.87)DDS(0.62)DS(0.477)DERNS(0.011)DGAVT(0.001)QNK;T(0.001)PLS(0.014)FT(0.254)NPLHS(0.71)DDS(0.506)DS(0.506)DERNS(0.008)DGAVT(0.001)QNK ;; 78.645 7.32E-06 63497000 5629.2 4283.1 4240.12 4340.12 5016.17 6364.4 4315.43 3357.08 5951.9 4921 TRUE FALSE FALSE 5183.64288 4653.312079 4397.262577 4322.161733 4956.355449 5044.351698 4436.509351 4380.638238 5298.991461 5092.004384 1.017996547 0.913846833 0.863562214 0.848813435 0.973360405 0.990641665 0.871269743 0.860297421 1.04064943 1 12.31401795 -7.231823924 6.328191437 1.008538855 0.904026468 0.569686455 0.046092337 0.114952029 15.94087536 0.007982401 0.00967595 5.86E-08 7.231823924 -0.104512387 TPLYLQPDAYGS(ph)LDR ddPTM_HeLa_Curcumin_4h_R1 3 TPLYLQPDAYGSLDR 15 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 0 TPLYLQPDAYGS(1)LDR;TPLYLQPDAYGS(1)LDR;TPLYLQPDAYGS(1)LDR ;; 149.19 0.00045175 302161000 6941.3 5993.3 6064.5 5799.5 6570 8706.4 7183.1 2988.29 7460.7 5838.5 TRUE FALSE FALSE 6391.888781 6511.334146 6289.255705 5775.503206 6491.657041 6900.594499 7384.638454 3899.405865 6642.279876 6041.38744 1.058016696 1.077787877 1.041028368 0.955989541 1.074530827 1.142220155 1.222341478 0.645448732 1.099462655 1 12.5606642 -4.245170892 24.76673293 1.047959199 0.645448382 0.74533958 0.073790532 1165.603282 1774453.695 0.01046353 0.368634727 5.69E-05 4.245170892 -0.402510817 TPMYGSQT(ph)PLQDGSR ddPTM_HeLa_Curcumin_4h_R1 2 TPMYGSQTPLQDGSR 15 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 0 TPMYGSQT(1)PLQDGSR;T(0.176)PMY(0.062)GS(0.239)QT(0.522)PLQDGSR ; 234.82 7.18E-21 30413000 2497.78 2107.79 2049.54 2533.92 2244.19 3747.5 2462.44 1657.08 2937.9 1994.52 TRUE FALSE FALSE 2300.078077 2289.977975 2125.497755 2523.43531 2217.4295 2970.226257 2531.529439 2162.316064 2615.61972 2063.829422 1.114471018 1.109577154 1.029880538 1.222695676 1.074424793 1.43918205 1.226617574 1.04772034 1.267362357 1 11.01110802 -6.10808423 1.391315578 1.056751239 1.224369654 0.047316394 0.125167748 0.372178494 1.42033988 0.017435887 0.035746617 7.80E-07 6.10808423 0.167618415 TPNNVVS(ph)TPAPS(ph)PDASQLASSLSSQK ddPTM_HeLa_Curcumin_4h_R1 1 TPNNVVSTPAPSPDASQLASSLSSQK 26 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424 Q8WWI1-3 LMO7 LIM domain only protein 7 2 0 T(0.001)PNNVVS(0.577)T(0.448)PAPS(0.958)PDAS(0.016)QLASSLSSQK 87.339 9.04E-05 13959000 4118.3 3676.4 3275.5 4245.4 3951.5 4198.4 2244.1 1988.8 4395.8 3661.6 TRUE FALSE FALSE 3792.332209 3994.171634 3396.892911 4227.83366 3904.380943 3327.604514 2307.063406 2595.175965 3913.591738 3788.840327 1.000921623 1.054193708 0.896552142 1.115864828 1.030494982 0.878264647 0.60891017 0.684952582 1.032926014 1 11.88754063 -4.925586086 3.378976267 1.006459544 0.646384797 0.870328901 0.056655098 0.052752611 1.19962145 0.007325484 0.025029028 1.19E-05 4.925586086 -0.360074746 TPNNVVST(ph)PAPSPDAS(ph)QLASSLSSQK ddPTM_HeLa_Curcumin_4h_R1 1 TPNNVVSTPAPSPDASQLASSLSSQK 26 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424 Q8WWI1-3 LMO7 LIM domain only protein 7 2 0 T(0.002)PNNVVS(0.218)T(0.657)PAPS(0.442)PDAS(0.677)QLAS(0.002)S(0.001)LSSQK 63.906 0.0020817 15397000 2594.1 2245.4 2123.3 2432.3 2142.8 2370.8 1533.1 1625.9 2621.9 2512.9 TRUE FALSE FALSE 2388.774248 2439.482371 2201.991366 2422.235787 2117.24851 1879.069356 1576.11466 2121.629425 2334.28413 2600.223088 0.9186805 0.938181951 0.846847094 0.931549219 0.814256484 0.722656977 0.606145937 0.815941307 0.897724561 1 11.34441969 -5.711622383 0.606714757 0.968199559 0.66866675 0.637746757 0.066490993 0.40668217 0.243480004 0.013194929 0.062467153 1.94E-06 5.711622383 -0.299532809 TPPGALLGAPPPLVPAPRPS(ph)SPPRGPGPAR ddPTM_HeLa_Curcumin_4h_R1 1 TPPGALLGAPPPLVPAPRPSSPPRGPGPAR 30 2 J3KNZ9;Q9HAH7 J3KNZ9 FBRS Probable fibrosin-1 1 0 TPPGALLGAPPPLVPAPRPS(0.5)S(0.5)PPRGPGPAR 55.871 0.00083987 21400000 557.12 453.95 370.03 356.89 351.9 537.58 409.15 171.09 461.8 597.72 TRUE FALSE FALSE 513.0233641 493.1874152 383.7436373 355.4132837 347.7038223 426.0798482 420.6296478 223.2545534 411.1416954 618.4907255 0.829476244 0.797404706 0.620451725 0.574646101 0.562181142 0.688902567 0.680090469 0.360966696 0.664749977 1 9.272608151 -7.220512877 0.420068725 1.001444682 0.526220136 0.339393242 0.13333093 0.331638736 0.152619707 0.045776976 0.055578051 6.02E-08 7.220512877 -0.475224546 TPPS(ph)PSGQPEEPGMVR ddPTM_HeLa_Curcumin_4h_R1 1 TPPSPSGQPEEPGMVR 16 0 M0R0S1;M0R2P6;Q8TBC3;M0QXA4;Q8TBC3-2 M0R0S1 SHKBP1 SH3KBP1-binding protein 1 1 0 T(0.001)PPS(0.971)PS(0.028)GQPEEPGMVR 137.91 3.15E-05 0 4019.8 3450.3 5525.9 5675.9 5671.7 5954 6644 5435.2 5168.4 4797.8 TRUE FALSE FALSE 3701.628588 3748.528558 5730.694715 5652.41463 5604.068682 4719.073285 6830.412759 7092.367459 4601.439451 4964.523193 0.745616134 0.755063158 1.154329327 1.138561431 1.128823145 0.950559218 1.375844667 1.428609996 0.926864328 1 12.27743945 -4.15689353 0.479061285 0.880432132 1.902137877 0.604190258 0.137917046 2.629095083 0.376629346 0.035409901 1.545084703 6.97E-05 4.15689353 1.021705746 TPPSEEDSAEAER ddPTM_HeLa_Curcumin_4h_R1 1 TPPSEEDSAEAER 13 0 O43765;K7EMD6 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 0 0 94.465 0.013784 515110 78.875 0 0 0 0 183.76 166.17 0 136.19 0 FALSE FALSE TRUE 72.63196052 0 0 0 0 145.6461046 170.832283 0 121.2502977 0 0 TPPSTTVGSHS(ph)PPETPVLTR ddPTM_HeLa_Curcumin_4h_R1 1 TPPSTTVGSHSPPETPVLTR 20 0 Q9ULU4-9;Q9ULU4-11;Q9ULU4-23;Q9ULU4-21;Q9ULU4;Q9ULU4-5;H7C4X9;A0A087WVZ6;Q9ULU4-10;Q9ULU4-13;Q9ULU4-20;Q9ULU4-12;Q9ULU4-7;Q9ULU4-19;Q9ULU4-16;Q9ULU4-22;Q9ULU4-18;Q9ULU4-14;Q9ULU4-15;Q9ULU4-6;Q9ULU4-3;Q9ULU4-4;Q9ULU4-2 Q9ULU4-9 ZMYND8 Protein kinase C-binding protein 1 1 0 TPPSTT(0.001)VGS(0.005)HS(0.994)PPET(0.001)PVLTR 161.55 8.03E-06 6901300 291.98 197.52 0 286.39 206.21 166.71 261.23 163.63 357.98 178.83 TRUE FALSE FALSE 268.8694749 214.5927487 0 285.2049941 203.7510804 132.1324668 268.5594107 213.5200337 318.7104896 185.0443292 1.453000349 1.159682924 0 1.541279299 1.101093351 0.71405845 1.451324728 1.153885854 1.722346699 1 7.531727114 -10.03392202 2.603673222 0.997036735 1.152406354 0 0.486678469 1.459897061 18.00947955 0.36421789 0.063493916 9.25E-11 10.03392202 0.155369619 TPPVAVT(ph)SPITHTAQSALK ddPTM_HeLa_Curcumin_4h_R1 1 TPPVAVTSPITHTAQSALK 19 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 TPPVAVT(0.499)S(0.499)PIT(0.001)HTAQSALK 106.47 0.00059421 14978000 871.6 864.9 948.42 953.16 1224.8 1652.3 1020.8 1458.3 1131.5 1045.1 TRUE FALSE FALSE 802.6119403 939.6581021 983.5692795 949.2160765 1210.19506 1309.594355 1049.440901 1902.928957 1007.377281 1081.417147 0.742185328 0.868913633 0.909518849 0.877752012 1.119082551 1.210998326 0.970431164 1.759662274 0.931534407 1 10.07870742 -1 0.663934416 0.883891111 78.60709669 0.769676174 0.129926219 83.06786018 0.472174174 0.024168491 9536.585686 0.1 1 77.72320558 TPPVAVTS(ph)PITHTAQSALK ddPTM_HeLa_Curcumin_4h_R1 1 TPPVAVTSPITHTAQSALK 19 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-6;Q8NEY1-5;H0Y6F6 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 T(0.04)PPVAVT(0.156)S(0.803)PITHTAQSALK 93.255 0.00076053 17567000 1004.4 901.05 531.41 761.56 759.49 995.13 1311.1 988.67 1090.1 675.29 TRUE FALSE FALSE 924.9006802 978.932747 551.1045221 758.4088665 750.4335778 788.7288206 1347.885937 1290.110932 970.5187573 698.7562772 1.323638456 1.400964512 0.788693483 1.085369665 1.073956116 1.12876098 1.928978646 1.846296017 1.388923132 1 9.448645528 -4.76302371 24.9940333 1.135851936 1.88763754 0.732538793 0.178442243 14.29025349 225459.439 0.025422793 0.082699582 1.73E-05 4.76302371 0.751785603 TPQEAIMDGTEIAVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 6 TPQEAIMDGTEIAVSPR 17 0 Q06587 Q06587 RING1 E3 ubiquitin-protein ligase RING1 1 0 TPQEAIMDGTEIAVS(1)PR;TPQEAIMDGTEIAVS(1)PR;TPQEAIMDGTEIAVS(1)PR;TPQEAIMDGT(0.004)EIAVS(0.996)PR;TPQEAIMDGTEIAVS(1)PR;TPQEAIMDGTEIAVS(1)PR ;;;;; 211.11 2.54E-11 65822500 5946.23 5335.68 5875.28 6112.63 5775.62 7655.29 5490.34 5509.2 6602.55 5683.58 TRUE FALSE FALSE 5475.579621 5796.872404 6093.023045 6087.337557 5706.749504 6067.496561 5644.384164 7188.929719 5878.266784 5881.083982 0.931049384 0.985680943 1.036037415 1.035070673 0.970356744 1.031696976 0.959752349 1.222381748 0.999520973 1 12.52186638 -4.258316684 24.83311679 0.981225281 1.222381846 0.786877706 0.035007141 100.7058528 800815.6052 0.005722087 0.054327476 5.52E-05 4.258316684 0.241156565 TPQEAITDGLEIVVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 TPQEAITDGLEIVVSPR 17 0 X6RFN3;Q99496-2;Q99496 X6RFN3 RNF2 E3 ubiquitin-protein ligase RING2 1 0 TPQEAITDGLEIVVS(1)PR 128.66 0.00034048 1928000 552.78 479.08 546.05 484.85 555.72 675.21 341.01 380.89 491.19 512.18 TRUE FALSE FALSE 509.0268797 520.4895405 566.2870934 482.8438192 549.093402 535.1638348 350.5778228 497.0216076 437.3076859 529.9782169 0.96046755 0.982096101 1.06851013 0.911063519 1.036067869 1.009784587 0.661494778 0.937815163 0.825142755 1 9.049789253 -4.786470109 24.99980982 0.98765574 0.799654884 0.369158985 0.089859172 99.63529568 99512.30463 0.008919995 0.02677538 1.64E-05 4.786470109 -0.188000856 LGPELSPSPTS(ph)PTATSTTPSR ddPTM_HeLa_Curcumin_4h_R1 1 LGPELSPSPTSPTATSTTPSR 21 0 M0QY76;P26651 M0QY76 ZFP36 Tristetraprolin 1 0 LGPELS(0.008)PS(0.302)PT(0.171)S(0.511)PT(0.007)ATSTTPSR 159.01 1.25E-06 8638600 1702.5 1354.1 1492.3 1489.6 1547.6 3040.5 2430.6 3618.4 1842.1 1267.7 TRUE FALSE FALSE 1567.745329 1471.14237 1547.605951 1483.43643 1529.145881 2409.866027 2498.796094 4721.633503 1640.026239 1311.752481 1.195153317 1.12150912 1.179800285 1.13088136 1.165727455 1.83713472 1.904929574 3.599485095 1.25025587 1 10.3572798 -1.31218434 0.706553941 1.093169211 200 0.964850224 0.139919484 18.41291276 0.145467386 0.021240477 5719.156525 0.04873216 1.31218434 198.9068308 up TPQNVPAS(ph)PGGDR ddPTM_HeLa_Curcumin_4h_R1 1 TPQNVPASPGGDR 13 0 H0YLX2;A0A669KBM4;Q2KHR2-2;Q2KHR2 H0YLX2 RFX7 DNA-binding protein RFX7 1 0 TPQNVPAS(1)PGGDR 134.88 0.0013256 16846000 4714.6 4164.7 4787.3 4236.7 4837.3 5189.2 3654.8 2563.8 3845.4 4056.6 TRUE FALSE FALSE 4341.434435 4524.67811 4964.721549 4219.169658 4779.618357 4112.901426 3757.343852 3345.490818 3423.569241 4197.566548 1.034274117 1.077928857 1.182761844 1.005146579 1.138664105 0.979829951 0.895124308 0.797007213 0.815608091 1 12.03533748 -4.661192836 2.184990103 1.040589792 0.803937008 0.408396344 0.092929225 0.177872689 1.523787931 0.009154264 0.05925627 2.18E-05 4.661192836 -0.236652784 TPS(ph)DDEEDNLFAPPK ddPTM_HeLa_Curcumin_4h_R1 1 TPSDDEEDNLFAPPK 15 0 A0A0A0MR88;A0A096LPC5;Q9Y4E1-6;Q9Y4E1;J3KP36;Q9Y4E1-3;Q9Y4E1-2;Q9Y4E1-1;Q641Q2;F8W7U3;E7ESD2;Q641Q2-2 A0A0A0MR88;Q641Q2 FAM21C;FAM21A WASH complex subunit FAM21C;WASH complex subunit FAM21A 1 0 T(0.027)PS(0.973)DDEEDNLFAPPK 123.1 0.0010903 28812000 6092.3 5357.2 6072.5 6230.3 6427.5 7217.7 6082 4877 5904.3 5696.3 TRUE FALSE FALSE 5610.088026 5820.252497 6297.552192 6204.520669 6350.85626 5720.66766 6252.644551 6363.974849 5256.613062 5894.246001 0.951790615 0.987446485 1.068423712 1.052640264 1.07746712 0.970551222 1.060804817 1.07969278 0.891821119 1 12.52509156 -6.837607035 6.016992263 0.976968858 1.049456656 0.538313875 0.041093262 0.123719616 7.511792909 0.005392708 0.007138787 1.45E-07 6.837607035 0.072487798 TPS(ph)GEFLER ddPTM_HeLa_Curcumin_4h_R1 2 TPSGEFLER 9 0 B3KT28;B1ANM7;Q9UNN5-2;Q9UNN5 B3KT28 FAF1 FAS-associated factor 1 1 0 T(0.013)PS(0.987)GEFLER;T(0.461)PS(0.539)GEFLER ; 120.63 0.0060719 41353000 3450.5 2921.5 2967.8 2946.9 3345.9 3463.3 2753.2 3304.6 3182 2648.3 TRUE FALSE FALSE 3177.389284 3174.021442 3077.789279 2934.706509 3306.002328 2744.972541 2830.447382 4312.157327 2832.942561 2740.328228 1.159492229 1.158263236 1.123146216 1.070932481 1.206425673 1.001694802 1.032886263 1.573591544 1.033796803 1 11.42013299 -4.25756752 24.9770814 1.08685614 1.573591734 0.819783941 0.068386312 134.300046 866323.3277 0.010878181 0.110675758 5.53E-05 4.25756752 0.486735594 PSMSPT(ph)PLDR ddPTM_HeLa_Curcumin_4h_R1 1 PSMSPTPLDR 10 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 PS(0.001)MS(0.291)PT(0.709)PLDR 139.86 0.0044819 32237000 2064.5 1916.3 2179.3 1924.8 2385 2408.1 2593.2 3087.6 1450.9 1714.4 TRUE FALSE FALSE 1901.092647 2081.936433 2260.066775 1916.835688 2356.560433 1908.632915 2665.958213 4028.995026 1291.7399 1773.975272 1.07165679 1.173599466 1.274012558 1.080531233 1.328406585 1.075907283 1.502815882 2.271167524 0.728161164 1 10.79277018 -1.26928453 0.810366969 1.069215628 199.9999974 0.845904188 0.154293095 63.68932014 0.326969924 0.018526522 23115.18695 0.053791725 1.26928453 198.9307818 up TPS(ph)PGPVESK ddPTM_HeLa_Curcumin_4h_R1 1 TPSPGPVESK 10 0 Q5T0W9 Q5T0W9 FAM83B Protein FAM83B 1 0 T(0.049)PS(0.951)PGPVESK 124.39 0.0038071 42413000 3209.6 2973.5 2791 3107.6 2841.6 2949.7 1802 1231.1 3594 3019 TRUE FALSE FALSE 2955.556773 3230.51609 2894.436915 3094.741575 2807.715776 2337.89897 1852.55927 1606.456723 3199.747192 3123.910025 0.946108162 1.034125844 0.926542984 0.990662839 0.898782536 0.748388702 0.593025809 0.514245516 1.024276361 1 11.60913719 -4.968146903 1.308855309 0.977425362 0.495776706 0.966577405 0.032189782 0.062140949 0.176762972 0.004523824 0.028144943 1.08E-05 4.968146903 -0.481648656 TPS(ph)PTPQPTSPQR ddPTM_HeLa_Curcumin_4h_R1 1 TPSPTPQPTSPQR 13 0 O15021;H7C1I9;O15021-2;O15021-3;O15021-6 O15021 MAST4 Microtubule-associated serine/threonine-protein kinase 4 1 0 T(0.24)PS(0.721)PT(0.034)PQPT(0.005)SPQR 113.43 0.0033138 3683000 990.56 752.51 986.47 724.17 1323.1 919.45 864.82 809.22 1030.6 834.99 TRUE FALSE FALSE 912.1561308 817.5536113 1023.029446 721.1735764 1307.322897 728.7457057 889.0845217 1055.947453 917.5457584 864.0058403 1.055729126 0.946236209 1.184053855 0.834685997 1.513094976 0.843449976 1.029026055 1.222153142 1.061967079 1 9.754897254 TPS(ph)SEEISPTK ddPTM_HeLa_Curcumin_4h_R1 1 TPSSEEISPTK 11 0 J3QLT3;E7ENF8;A0A1W2PRI7;Q15311 J3QLT3 RALBP1 RalA-binding protein 1 1 0 T(0.205)PS(0.397)S(0.397)EEIS(0.001)PTK 158.34 0.00038157 24854000 2018.2 2527.2 2067 2392.7 3009.3 2845.5 2290 1426.5 1846.3 1899.4 TRUE FALSE FALSE 1858.45734 2745.639907 2143.604838 2382.799641 2973.416063 2255.311225 2354.251237 1861.433283 1643.765509 1965.404009 0.945585402 1.396984994 1.090668803 1.212371416 1.512877785 1.147505151 1.197845953 0.947099566 0.836349932 1 10.94061019 -7.286550184 24.75598049 0.974304204 1.218358858 0.416150785 0.153143193 503.5884928 496471.2362 0.024304966 0.02779958 5.17E-08 7.286550184 0.244054655 TPS(ph)SPCPASK ddPTM_HeLa_Curcumin_4h_R1 1 TPSSPCPASK 10 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 T(0.172)PS(0.491)S(0.336)PCPAS(0.001)K 95.477 0.015578 38766000 7231.6 5107.1 6636.8 6667.1 6111.8 7746.8 6682.4 2572.2 7026.1 6198.2 TRUE FALSE FALSE 6659.211229 5548.534967 6882.765646 6639.513307 6038.920777 6140.026356 6869.890159 3356.451939 6255.354408 6413.586989 1.038297483 0.865121963 1.073153862 1.035226203 0.941582423 0.957346703 1.071146329 0.523334593 0.975328536 1 12.64691574 -4.256766009 24.99901145 1.006541974 0.523334398 0.839502957 0.061724137 125.416698 670861.4317 0.007962157 0.085791244 5.54E-05 4.256766009 -0.483207576 TPS(ph)SSSTLAYSPR ddPTM_HeLa_Curcumin_4h_R1 1 TPSSSSTLAYSPR 13 0 H3BR17;Q6Q0C0;A0A087WUB0 H3BR17 TRAF7 E3 ubiquitin-protein ligase TRAF7 1 0 T(0.158)PS(0.53)S(0.018)S(0.167)S(0.051)T(0.076)LAYSPR 113.25 0.0033523 14803000 607.55 530.16 447.39 691.53 735.14 666.67 453.42 476.55 521.24 553.81 TRUE FALSE FALSE 559.4617764 575.9846681 463.970667 688.6686321 726.3739356 528.3951271 466.1417449 621.8479012 464.0612761 573.0548563 0.976279618 1.00511262 0.80964442 1.201749928 1.267546951 0.92206727 0.813433024 1.085145505 0.809802536 1 9.162529439 -6.253988786 24.90511978 0.977782201 1.048493055 0.131075268 0.142050242 1384.401621 4627639.69 0.020649094 0.03381898 5.57E-07 6.253988786 0.070710853 TPS(ph)VTEASPWR ddPTM_HeLa_Curcumin_4h_R1 2 TPSVTEASPWR 11 0 A0A3B3IU55;Q8WXE9;Q8WXE9-3 A0A3B3IU55 STON2 Stonin-2 1 0 T(0.31)PS(0.689)VT(0.001)EASPWR;T(0.356)PS(0.643)VT(0.001)EASPWR ; 117.86 0.0044779 15738700 2154.34 2046.6 2064.16 2465.44 1689.65 2341.36 2001.73 2338.5 2089.99 1733.84 TRUE FALSE FALSE 1983.821716 2223.498985 2140.659585 2455.238663 1669.502027 1855.735543 2057.893156 3051.497885 1860.723326 1794.090811 1.105753234 1.239345841 1.19317237 1.368514151 0.930556033 1.034359873 1.147039572 1.700860328 1.03713999 1 10.8090372 -4.26407828 4.034557664 1.08804146 1.753336038 0.666704578 0.122899841 0.106125991 3.63419145 0.018153711 0.204577907 5.44E-05 4.26407828 0.665294579 TPSKPPAQLS(ph)PSVPK ddPTM_HeLa_Curcumin_4h_R1 1 TPSKPPAQLSPSVPK 15 1 F5H8D7;P18887;M0QYS5 F5H8D7 XRCC1 DNA repair protein XRCC1 1 0 TPSKPPAQLS(0.911)PS(0.089)VPK 98.882 0.0018993 19242000 1443.4 1156.3 1271.7 1639.3 1407 1806.8 1474.2 1645.8 1625.1 1533.1 TRUE FALSE FALSE 1329.153367 1256.24542 1318.830321 1632.517011 1390.222444 1432.049313 1515.562084 2147.596844 1446.830596 1586.375111 0.837855661 0.791896829 0.831348344 1.029086374 0.876351649 0.902717966 0.955361739 1.353776184 0.912035612 1 10.63151823 -4.25791517 3.612968041 0.909302063 1.405934862 0.790581781 0.069787274 0.117251839 2.734693067 0.011697551 0.157409724 5.52E-05 4.25791517 0.496632799 TPSLS(ph)PASSLDV ddPTM_HeLa_Curcumin_4h_R1 1 TPSLSPASSLDV 12 0 B7WPE2;Q32P44;H7C355;G3V195 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 0 T(0.082)PS(0.057)LS(0.857)PAS(0.004)SLDV 103.08 0.0076361 1681800 424.83 334.91 590.86 615.08 370.55 525.7 566.24 673.56 518.76 495.96 TRUE FALSE FALSE 391.2042572 363.8581281 612.7577914 612.5349619 366.1314333 416.6638941 582.1271704 878.9253433 461.8533259 513.1945731 0.762292272 0.709006188 1.194006764 1.193572563 0.713435902 0.811902378 1.134320589 1.712655179 0.899957541 1 9.003362104 -4.322882436 2.697716531 0.900519346 1.813906702 0.672592838 0.168579081 0.183195273 1.909750761 0.025498433 0.347500081 4.75E-05 4.322882436 0.913387356 TPSNTPSAEADWS(ph)PGLELHPDYK ddPTM_HeLa_Curcumin_4h_R1 3 TPSNTPSAEADWSPGLELHPDYK 23 0 Q9Y3Z3-3;Q9Y3Z3-4;Q9Y3Z3;A0A2R8Y7R5;A0A2R8Y755;A0A2R8Y586;A0A2R8YF51;A0A2R8Y5D2;A0A2R8YCS7 Q9Y3Z3-3 SAMHD1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 1 0 T(0.007)PS(0.007)NT(0.043)PS(0.093)AEADWS(0.829)PGLELHPDY(0.02)K;TPSNT(0.001)PS(0.002)AEADWS(0.996)PGLELHPDYK;T(0.013)PS(0.014)NT(0.073)PS(0.155)AEADWS(0.743)PGLELHPDY(0.002)K ;; 92.901 7.17E-05 113283000 7489.2 7077.7 7963.1 7401.9 7842.6 9297.4 5831.5 5715.2 8370 7434.6 TRUE FALSE FALSE 6896.421917 7689.46485 8258.219491 7371.272899 7749.082117 7369.014437 5995.116195 7457.73817 7451.831941 7692.951797 0.896459785 0.999546735 1.073478648 0.958185245 1.007296331 0.957891669 0.779299852 0.969424789 0.968657043 1 12.90932155 -4.962127966 24.92412786 0.967559193 0.872920468 0.308974662 0.061721702 162.6619513 107048.4389 0.009231122 0.027693281 1.09E-05 4.962127966 -0.094638724 TPSPKEEDEEPES(ph)PPEK ddPTM_HeLa_Curcumin_4h_R1 2 TPSPKEEDEEPESPPEK 17 1 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 T(0.001)PS(0.001)PKEEDEEPES(0.999)PPEK;TPS(0.001)PKEEDEEPES(0.999)PPEK ; 74.657 0.0062956 26917000 4226.8 3595.5 3592.9 4186.9 3882.5 4777.6 4171.8 3960.7 4714.2 4213 TRUE FALSE FALSE 3892.24432 3906.278999 3726.056035 4169.575717 3836.203723 3786.671905 4288.84948 5168.299197 4197.064054 4359.401436 0.892839161 0.896058566 0.854717348 0.956456013 0.879984048 0.86862198 0.983816137 1.185552483 0.962761543 1 12.08991435 -4.298535549 3.339598873 0.92893848 1.209774666 0.753802308 0.046034629 0.133441872 2.468499109 0.007979196 0.090442865 5.03E-05 4.298535549 0.280836186 TPSPKEEDEEPES(ph)PPEKK ddPTM_HeLa_Curcumin_4h_R1 1 TPSPKEEDEEPESPPEKK 18 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 TPSPKEEDEEPES(1)PPEKK 103.31 0.00081143 263160000 3244.5 2603.6 2896.2 2775.2 2988.5 3721.8 3229 3471.7 3724.5 3413 TRUE FALSE FALSE 2987.694401 2828.643583 3003.53572 2763.716958 2952.864089 2949.856727 3319.59705 4530.205348 3315.931668 3531.601496 0.845988542 0.800952085 0.850474133 0.782567614 0.836126073 0.835274515 0.939969318 1.282762326 0.938931437 1 11.78610684 -4.269796731 3.730083641 0.889408117 1.32104268 0.778993826 0.065745665 0.122736171 3.217836881 0.012243472 0.143962838 5.37E-05 4.269796731 0.431634564 TPSS(ph)PSKSPASFEIPASAMEANGVDGDGLNKPAK ddPTM_HeLa_Curcumin_4h_R1 1 TPSSPSKSPASFEIPASAMEANGVDGDGLNKPAK 34 2 H0Y911;Q4VXL4;D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-2;O95359-6;O95359-1;O95359-5;O95359-3;O95359;E9PGB3;H0YA73 H0Y911 TACC2 Transforming acidic coiled-coil-containing protein 2 1 0 T(0.119)PS(0.127)S(0.208)PS(0.208)KS(0.152)PAS(0.152)FEIPAS(0.034)AMEANGVDGDGLNKPAK 51.321 0.0019114 33348000 1930.1 1600.8 1735.4 1914.2 1745.8 2509.8 1900.8 1637.6 2266.4 2047.4 TRUE FALSE FALSE 1777.330548 1739.166019 1799.715451 1906.279548 1724.982475 1989.239189 1954.131332 2136.896701 2017.78159 2118.546998 0.838938457 0.820923973 0.849504615 0.899805173 0.814229034 0.938963918 0.92239225 1.008661457 0.952436549 1 11.04885942 -2.16812024 14.57532555 0.907971132 0.895057481 0 0.068094687 0 0 0.010727945 0 0.006790156 2.16812024 -0.012913651 TPSS(ph)PSKSPASFEIPASAMEANGVDGDGLNKPAKK ddPTM_HeLa_Curcumin_4h_R1 1 TPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKK 35 3 H0Y911;Q4VXL4;D6RAA5;Q4VXL8;E7EMZ9;E9PBC6;O95359-2;O95359-6;O95359-1;O95359-5;O95359-3;O95359;E9PGB3;H0YA73 H0Y911 TACC2 Transforming acidic coiled-coil-containing protein 2 1 0 T(0.115)PS(0.115)S(0.328)PS(0.328)KS(0.102)PAS(0.012)FEIPASAMEANGVDGDGLNKPAKK 51.306 0.0029006 11002000 1379.7 1010.7 1135.3 1049.1 1082.3 1170.1 989.72 1067.8 1664.8 1109.6 TRUE FALSE FALSE 1270.495289 1098.060404 1177.375217 1044.759102 1069.394279 927.4080703 1017.48888 1393.367304 1482.175605 1148.158517 1.10655042 0.956366554 1.025446573 0.909943258 0.931399509 0.807735218 0.886191988 1.213567015 1.290915481 1 10.16510612 -6.733938378 1.706917432 1.04834107 0.940164511 0.178651978 0.129835835 0.470804685 2.79645929 0.018124223 0.02662338 1.85E-07 6.733938378 -0.10817656 TPSS(ph)SPPITPPASETK ddPTM_HeLa_Curcumin_4h_R1 1 TPSSSPPITPPASETK 16 0 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 0 T(0.167)PS(0.014)S(0.409)S(0.409)PPITPPASETK 145.7 0.00036996 27356000 3601.5 2595.2 2803.1 3273 3065.7 3717.5 3699.3 3856.9 3344.1 3000.8 TRUE FALSE FALSE 3316.437475 2819.517524 2906.985352 3259.457193 3029.14353 2946.448595 3803.092402 5032.851055 2977.260597 3105.077577 1.06806912 0.908034487 0.936203776 1.049718441 0.975545201 0.948913038 1.22479787 1.620845512 0.95883614 1 11.6004136 -4.360637931 2.505959983 1.010028204 1.687912789 0.923872205 0.056056835 0.084140777 0.755820453 0.008460916 0.109285949 4.36E-05 4.360637931 0.677884585 TPSSDVLVFDYTK ddPTM_HeLa_Curcumin_4h_R1 1 TPSSDVLVFDYTK 13 0 E9PC52;Q16576;Q16576-2;Q5JP01;Q09028-3;Q09028;Q09028-2;Q09028-4;H0YF10 E9PC52;Q09028-3 RBBP7;RBBP4 Histone-binding protein RBBP7;Histone-binding protein RBBP4 0 0 131.42 0.0012711 468280 597.08 564.61 441.13 346.69 757.07 1007.3 691.64 613.47 1070.6 410.59 FALSE FALSE TRUE 549.820488 613.4123725 457.4786659 345.2554886 748.0424347 798.3746254 711.0455569 800.5141789 953.1578585 424.8579719 1.294127742 1.443805726 1.076780233 0.812637426 1.76068824 1.879156514 1.673607662 1.88419244 2.243474105 1 8.730836825 -5.7019088 9.580043684 1.14211247 1.79806712 0.210717121 0.38611561 0.141144753 21.5169898 0.027262735 0.054526678 1.99E-06 5.7019088 0.65595465 TPSSS(ph)PPITPPASETK ddPTM_HeLa_Curcumin_4h_R1 1 TPSSSPPITPPASETK 16 0 F5GZ90;Q9NZJ0 F5GZ90 DTL Denticleless protein homolog 1 0 T(0.003)PS(0.012)S(0.063)S(0.911)PPIT(0.012)PPASETK 100.38 0.0028109 13944000 3978.1 2994.9 3631.8 3311.4 3355.4 4587.8 4179.6 4155.8 3720 3242.7 TRUE FALSE FALSE 3663.229187 3253.765811 3766.397703 3297.698304 3315.389046 3636.238565 4296.868327 5422.884289 3311.925307 3355.383584 1.091746769 0.969715006 1.122493929 0.982808142 0.988080487 1.083702794 1.280589304 1.616174173 0.987048194 1 11.71226199 -4.367959687 1.75843736 1.036349932 1.738829687 0.932259007 0.049682659 0.130517516 0.46945293 0.007331378 0.141698139 4.29E-05 4.367959687 0.702479755 TPT(ph)PEPAEVETRK ddPTM_HeLa_Curcumin_4h_R1 1 TPTPEPAEVETRK 13 1 F8W6G1;Q9UHY1 F8W6G1 NRBP1 Nuclear receptor-binding protein 1 0 T(0.375)PT(0.612)PEPAEVET(0.013)RK 98.942 0.0021901 0 1075.5 866.06 765.58 1135.6 737.51 1208.2 729.33 578.6 1116.8 817.18 TRUE FALSE FALSE 990.3730401 940.9183673 793.9530683 1130.901188 728.7156749 957.6057008 749.7930369 755.0124765 994.2898341 845.5769442 1.171239409 1.112753102 0.93894834 1.337431438 0.861797001 1.132487951 0.886723606 0.892896243 1.175871505 1 9.72379223 -4.657079869 1.390748932 1.083519808 0.847228574 0.250390785 0.130009855 0.714183535 1.959102598 0.018003622 0.192061685 2.20E-05 4.657079869 -0.236291234 TPT(ph)PEPFDSETR ddPTM_HeLa_Curcumin_4h_R1 2 TPTPEPFDSETR 12 0 Q9NSY0;H0YCB1;Q9NSY0-2;Q9NSY0-4 Q9NSY0 NRBP2 Nuclear receptor-binding protein 2 1 0 T(0.419)PT(0.581)PEPFDSETR;T(0.052)PT(0.947)PEPFDSETR ; 131.32 0.0066711 14704200 2707.5 3009.6 2877.7 2769.8 2329.5 1103.76 1203.67 2176.1 3095.2 3245 TRUE FALSE FALSE 2493.198518 3269.736413 2984.350093 2758.339302 2301.722234 874.8277341 1237.441741 2839.582872 2755.664304 3357.763508 0.742517605 0.97378401 0.888791032 0.821481112 0.685492658 0.260538818 0.368531535 0.845676852 0.820684452 1 11.71328491 -5.598287581 3.162612427 0.881526094 0.477555654 0.54115044 0.157344895 0.141959147 2.857270289 0.024305338 0.052865301 2.52E-06 5.598287581 -0.40397044 QTS(ph)IETDR ddPTM_HeLa_Curcumin_4h_R1 1 QTSIETDR 8 0 E9PFK9;Q9UJ41;Q9UJ41-4;Q9UJ41-3 E9PFK9 RABGEF1 Rab5 GDP/GTP exchange factor 1 0 QT(0.004)S(0.994)IET(0.002)DR 112.94 0.010437 63497000 2547.4 2014.7 2567.9 2888.6 2960.7 4217.4 4522.3 6311.7 2494.7 2021.9 TRUE FALSE FALSE 2345.770602 2188.841691 2663.068633 2876.647739 2925.395586 3342.6637 4649.183567 8236.108275 2221.037651 2092.160875 1.121219037 1.046210986 1.272879474 1.374964886 1.398265125 1.597708733 2.222192195 3.936651514 1.061599841 1 11.03077808 -1.226803901 0.663090717 1.075725808 200 0.987763629 0.094065109 12.07523222 0.096134618 0.017912812 3503.062955 0.059319311 1.226803901 198.9242742 up TPT(ph)SSPASSPLVAK ddPTM_HeLa_Curcumin_4h_R1 1 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 0 T(0.157)PT(0.388)S(0.265)S(0.182)PAS(0.007)S(0.002)PLVAK 113.54 0.0070554 85147000 5027.5 4483.9 5155.5 5110.2 4126.4 5965 3898 2065.1 4909.3 4534 TRUE FALSE FALSE 4629.56807 4871.468336 5346.567365 5089.055346 4077.195375 4727.791761 4007.367389 2694.739483 4370.762072 4691.556163 0.986787307 1.038348081 1.139614912 1.084726511 0.869049679 1.007723578 0.854165921 0.574380736 0.931623095 1 12.19585082 -3.918750194 1.172460269 1.009565176 0.02270837 0.7807672 0.070427027 1.014866515 0.670218553 0.010116815 1.481285536 0.000120573 3.918750194 -0.986856806 TPTCQSSTDCS(ph)PYAR ddPTM_HeLa_Curcumin_4h_R1 2 TPTCQSSTDCSPYAR 15 0 O95235-2;O95235 O95235-2 KIF20A Kinesin-like protein KIF20A 1 0 TPTCQSSTDCS(1)PYAR;TPTCQSSTDCS(0.999)PYAR ; 218.34 2.26E-14 29542000 2129.62 1731.41 1511.91 1759.62 2295.7 2793.5 2189.05 587.47 2539.9 1668.07 TRUE FALSE FALSE 1961.05833 1881.065365 1567.942715 1752.339159 2268.325277 2214.096611 2250.468851 766.5868986 2261.279325 1726.035308 1.136163507 1.08981859 0.908407092 1.015239462 1.314182431 1.282764379 1.303837089 0.444131644 1.310100271 1 10.75324626 TPTGEGLLDS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 2 TPTGEGLLDSPSK 13 0 O95425-3;A0A6I8PIX7;O95425-2;O95425;O95425-4;A0A0J9YWY6 O95425-3 SVIL Supervillin 1 0 TPTGEGLLDS(0.995)PS(0.005)K;T(0.009)PTGEGLLDS(0.989)PS(0.002)K ; 174.24 0.00020968 173759000 8161 7646.5 8694.8 7483.1 8747.7 10871 9603.2 3521.1 8656.6 6893.9 TRUE FALSE FALSE 7515.048239 8307.429388 9017.036937 7452.136915 8643.389391 8616.232059 9872.639946 4594.667181 7706.992638 7133.462512 1.053492357 1.164571815 1.264047708 1.044673173 1.211668159 1.207861126 1.383989883 0.644100558 1.080399964 1 12.8003868 -7.423300876 3.116077365 1.021852908 1.148830425 0.035827993 0.186044498 0.454114758 8.144404664 0.030383975 0.034067972 3.77E-08 7.423300876 0.126977517 GLGKPGGQGDAIQLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 GLGKPGGQGDAIQLSPK 17 1 Q5VV41 Q5VV41 ARHGEF16 Rho guanine nucleotide exchange factor 16 1 0 GLGKPGGQGDAIQLS(1)PK;GLGKPGGQGDAIQLS(1)PK ; 100.53 0.00090971 137364000 9301.7 7484 7958.6 9130.4 8558.5 9850.2 7413.4 2826.7 9357.3 8077.9 TRUE FALSE FALSE 8565.46063 8130.883612 8253.552717 9092.620824 8456.445477 7807.157485 7621.400052 3688.547817 8330.827601 8358.606424 1.024747451 0.972755888 0.987431672 1.087815404 1.011705187 0.934026211 0.911802718 0.441287414 0.99667662 1 13.02904672 -4.063820819 1.672670024 1.010629619 2.44E-18 0.954415311 0.036593179 0.232987191 0.417258832 0.005109506 0.4405142 8.63E-05 4.063820819 -1.010629619 down TPTSS(ph)PASS(ph)PLVAK ddPTM_HeLa_Curcumin_4h_R1 1 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 2 0 T(0.212)PT(0.095)S(0.095)S(0.589)PAS(0.133)S(0.876)PLVAK 93.228 0.019737 9247200 3474.5 2724.5 3944.4 3689.5 3092 4265.7 3388.2 1071.2 4007.8 3506.5 TRUE FALSE FALSE 3199.489659 2959.99364 4090.582934 3674.233827 3055.129919 3380.945736 3483.263773 1397.803949 3568.154367 3628.350614 0.88180278 0.815795923 1.127394612 1.012645749 0.842016179 0.931813404 0.960013004 0.385245005 0.983409474 1 11.82509816 -4.260462724 24.6437163 0.944519214 0.385244787 0.794981828 0.086073582 23.09685238 582689.4053 0.012176376 0.099470317 5.49E-05 4.260462724 -0.559274427 NLS(ph)SDEATNPISR ddPTM_HeLa_Curcumin_4h_R1 3 NLSSDEATNPISR 13 0 Q7Z417 Q7Z417 NUFIP2 Nuclear fragile X mental retardation-interacting protein 2 1 0 NLS(0.92)S(0.08)DEATNPISR;NLS(0.788)S(0.21)DEAT(0.003)NPISR;NLS(0.498)S(0.498)DEAT(0.004)NPISR ;; 213.83 2.09E-13 421270000 4303.7 3648.8 3948.8 3911.9 3980.8 4416.4 3386.2 1273.84 4049.8 3418.77 TRUE FALSE FALSE 3963.057604 3964.186013 4095.146002 3895.713594 3933.33156 3500.388857 3481.207659 1662.227952 3605.547072 3537.572003 1.120276167 1.120595145 1.157614883 1.101239379 1.111873216 0.989489077 0.984066941 0.469878196 1.019215176 1 11.7885438 -4.062436923 1.759884197 1.074836544 6.56E-16 0.919830052 0.053560328 0.38375799 0.765346326 0.009185907 0.808146859 8.66E-05 4.062436923 -1.074836544 down TPTSSPAS(ph)SPLVAK ddPTM_HeLa_Curcumin_4h_R1 2 TPTSSPASSPLVAK 14 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 0 T(0.006)PT(0.001)SS(0.008)PAS(0.844)S(0.14)PLVAK;T(0.011)PT(0.001)S(0.001)S(0.237)PAS(0.691)S(0.058)PLVAK ; 195.87 3.15E-06 72001000 6881.5 5494.9 5802.5 5631.1 5361.9 6490.8 4527.1 2665.3 6486.5 5217.5 TRUE FALSE FALSE 6336.822014 5969.854671 6017.545754 5607.8 5297.962844 5144.534914 4654.118242 3477.9377 5774.947178 5398.807737 1.173744709 1.105772786 1.114606418 1.038710818 0.981320896 0.952902041 0.862064083 0.644204771 1.069670835 1 12.39842512 -3.860669404 0.69403556 1.086954245 0.112265406 0.899188457 0.045871005 1.458504282 0.335531181 0.011633655 1.268221036 0.000137826 3.860669404 -0.974688839 YTPPTQPPIS(ph)PPYQEACTLKR ddPTM_HeLa_Curcumin_4h_R1 1 YTPPTQPPISPPYQEACTLKR 21 1 B7Z4K4;Q9UET6-2;Q9UET6 B7Z4K4 FTSJ1 Putative tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase 1 0 YTPPTQPPIS(1)PPYQEACTLKR 124.81 6.74E-05 0 652.88 588.99 769.11 559.11 771.39 1128 893.5 1179.9 818.61 743.34 TRUE FALSE FALSE 601.2038591 639.8996711 797.6138932 556.796551 762.1916781 894.0400848 918.5692053 1539.646078 728.8105311 769.1710097 0.781625739 0.831934203 1.036978621 0.723891754 0.990926164 1.16234241 1.194232744 2.001695408 0.947527301 1 9.587160578 -1.226472704 0.812034707 0.890291171 199.9999996 0.905236893 0.105691532 74.74161619 0.352918802 0.01828955 27251.64371 0.059364566 1.226472704 199.1097084 up TPVCHQCHK(ac)VIR ddPTM_HeLa_Curcumin_4h_R1 2 TPVCHQCHKVIR 12 1 Q9NR12-2;Q9NR12 Q9NR12-2 PDLIM7 PDZ and LIM domain protein 7 0 1 ; TPVCHQCHK(1)VIR;TPVCHQCHK(1)VIR 79.036 0.0066671 1399540 647.31 703.68 732.22 551.25 666.2 641.74 645.73 331.77 535.33 649.02 FALSE TRUE FALSE 596.0747305 764.5029637 759.3567173 548.9690736 658.2560001 508.6358901 663.8474459 432.9251457 476.6056383 671.5733967 0.887579427 1.138375891 1.130712921 0.817437195 0.980169857 0.75737945 0.988495746 0.644643084 0.709685108 1 9.391401271 -5.272416184 24.41975948 0.96659699 0.816005059 0.182524949 0.146558207 552.3973334 1228902.144 0.017289584 0.039026964 5.34E-06 5.272416184 -0.150591931 TPVDDPMSLLY(ph)NMNDCY(ph)S(ph)KLK ddPTM_HeLa_Curcumin_4h_R1 1 TPVDDPMSLLYNMNDCYSKLK 21 1 Q02363 Q02363 ID2 DNA-binding protein inhibitor ID-2 3 0 TPVDDPMS(0.001)LLY(1)NMNDCY(1)S(1)KLK 54.974 0.0055666 0 358.09 324.01 448.86 337.94 776.82 1079.3 475.59 540.94 885.79 379.06 TRUE FALSE FALSE 329.7467986 352.0159806 465.4951465 336.5416938 767.5569289 855.4410138 488.9337754 705.8701158 788.6210531 392.2323068 0.840692602 0.897468094 1.186784307 0.858016252 1.956893697 2.180955008 1.246541315 1.79962258 2.010596882 1 8.61556456 -5.765243768 24.99998388 0.938406735 1.784252492 0.32720639 0.413438191 35.09795667 230643.1423 0.034449062 0.064205266 1.72E-06 5.765243768 0.845845757 TPVDES(ph)DDEIQHDEIPTGK ddPTM_HeLa_Curcumin_4h_R1 4 TPVDESDDEIQHDEIPTGK 19 0 Q86TC9;A0A087WX60;Q86TC9-2 Q86TC9 MYPN Myopalladin 1 0 T(0.098)PVDES(0.895)DDEIQHDEIPT(0.006)GK;T(0.016)PVDES(0.984)DDEIQHDEIPTGK;T(0.014)PVDES(0.986)DDEIQHDEIPTGK;T(0.093)PVDES(0.907)DDEIQHDEIPTGK ;;; 138.09 9.90E-05 997321600 11078 9808.1 9746.5 10358.2 10498.1 12166.8 9439.7 5913.33 12357.9 9843.9 TRUE FALSE FALSE 10201.16461 10655.86846 10107.71386 10315.34051 10372.91701 9643.268532 9704.552576 7716.277095 11002.26929 10185.97479 1.001491248 1.046131438 0.992316795 1.012700377 1.018352904 0.946720243 0.952736756 0.757539387 1.080139065 1 13.31429643 -3.552416246 1.093550773 1.004945935 5.46E-14 0.856884606 0.031489961 1.139116411 0.356538663 0.002902119 1.93120952 0.000280275 3.552416246 -1.004945935 TPVEPEVAIHR ddPTM_HeLa_Curcumin_4h_R1 5 TPVEPEVAIHR 11 0 P60866;P60866-2;E5RIP1;E5RJX2 P60866 RPS20 40S ribosomal protein S20 0 0 ;;;; ;;;; 164.33 0.0001606 28282200 20366 17176.1 19582.9 19788.9 20365.9 17197.7 15004.3 14032.3 18781.1 16861.8 FALSE FALSE TRUE 18754.00961 18660.72555 20308.6595 19707.01878 20123.04994 13630.70316 15425.28028 18310.68367 16720.86032 17447.74629 1.074867166 1.069520684 1.163970358 1.129487926 1.153332333 0.781230019 0.884084398 1.049458386 0.958339263 1 14.09075308 -5.268255459 24.99893485 1.062683112 0.902840279 0.451938058 0.086364931 384.5269319 1410308.182 0.012421249 0.028357629 5.39E-06 5.268255459 -0.159842833 TPVQYSQQQNS(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 3 TPVQYSQQQNSPQK 14 0 P46013 P46013 MKI67 Antigen KI-67 1 0 TPVQYSQQQNS(1)PQK;TPVQYSQQQNS(1)PQK;T(0.039)PVQYSQQQNS(0.961)PQK ;; 249.36 4.34E-30 38006900 5127.81 3912.15 4515.54 5469.63 5180.6 6694.3 5545.5 2551.87 5715.7 4874.8 TRUE FALSE FALSE 4721.938428 4250.298814 4682.889885 5446.99812 5118.824729 5305.82672 5701.091805 3329.923416 5088.70201 5044.198937 0.936112649 0.842611258 0.928371371 1.079853945 1.014794379 1.051867063 1.130227391 0.660149105 1.008822624 1 12.30040946 TPVSGSLKS(ph)PVPR ddPTM_HeLa_Curcumin_4h_R1 1 TPVSGSLKSPVPR 13 1 H0Y7U4;A0A0C4DG98;Q8NI27-2;Q8NI27;H7C477 H0Y7U4 THOC2 THO complex subunit 2 1 0 TPVSGSLKS(1)PVPR 130.66 0.015364 61323000 1695.1 1435.6 1193.5 1343.9 1142.4 1819.8 1306.7 895.43 1403.4 1466.5 TRUE FALSE FALSE 1560.931046 1559.686867 1237.73216 1338.339298 1128.777626 1442.352967 1343.362485 1168.442485 1249.450531 1517.460766 1.028646724 1.027826816 0.815660074 0.881959737 0.743859513 0.950504289 0.885269995 0.769998481 0.823382429 1 10.5674435 -6.764958752 24.9997932 1.014978047 0.845606801 0.316560587 0.08255258 36.72479779 260874.252 0.008538274 0.011474663 1.72E-07 6.764958752 -0.169371246 TQAEK(ac)GDTENGKEK ddPTM_HeLa_Curcumin_4h_R1 1 TQAEKGDTENGKEK 14 2 Q9H981 Q9H981 ACTR8 Actin-related protein 8 0 1 TQAEK(1)GDTENGKEK 84.508 0.0057444 2324100 1355.4 1234.9 1195.3 1508.9 1346 1782.4 1254.1 1211 1484.5 1545.1 FALSE TRUE FALSE 1248.11866 1341.639253 1239.598869 1502.656572 1329.949829 1412.710148 1289.286671 1580.228325 1321.654064 1598.79211 0.78066351 0.83915804 0.775334618 0.939869894 0.83184663 0.883610908 0.806412956 0.988388869 0.82665786 1 10.64276664 -9.481872101 1.230197235 0.999788184 0.846047019 0 0.083125042 0.335436864 0.910249548 0.043170881 0.010624616 3.30E-10 9.481872101 -0.153741165 TQARPVGVK(ac)IPTCK ddPTM_HeLa_Curcumin_4h_R1 1 TQARPVGVKIPTCK 14 2 G3V438;H0YJG7;O95433-2;O95433 G3V438 AHSA1 Activator of 90 kDa heat shock protein ATPase homolog 1 0 1 TQARPVGVK(1)IPTCK 119.62 0.00018598 4514300 1809.3 1720.2 1568.7 1684.9 1542.1 2514.6 1825.9 1936.5 1828.3 1492.7 FALSE TRUE FALSE 1666.091996 1868.886423 1626.837402 1677.92833 1523.711465 1993.043615 1877.12984 2526.929935 1627.740064 1544.571214 1.078676063 1.20997103 1.053261505 1.086339248 0.986494796 1.290353981 1.215308056 1.6360074 1.053845915 1 10.59299067 -1.000000004 0.675314028 1.049866791 61.98113433 0.813365102 0.079603656 67.55011684 0.368004392 0.013266987 6197.165218 0.099999999 1.000000004 60.93126754 TQASSS(ph)FQDSSQPAGK ddPTM_HeLa_Curcumin_4h_R1 1 TQASSSFQDSSQPAGK 16 0 P46087;P46087-4;P46087-2 P46087;P46087-2 NOP2 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase 1 0 TQASS(0.019)S(0.981)FQDSSQPAGK 314.61 9.53E-112 8073700 2853.3 2157.9 2234.6 2823.6 2538 5023 5189.3 1097.6 3480.9 2114 TRUE FALSE FALSE 2627.458294 2344.419261 2317.416242 2811.916691 2507.736008 3981.173179 5334.897792 1432.253187 3099.053979 2187.461343 1.201145018 1.071753459 1.059409004 1.285470347 1.146413863 1.819997045 2.438853518 0.654755885 1.416735427 1 11.09504181 -5.271520263 19.94737093 1.110122477 1.717967217 0.187879526 0.425562812 36.47423331 72175.20439 0.053215035 0.120965997 5.35E-06 5.271520263 0.607844739 HGLQLGAQS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 1 HGLQLGAQSPGR 12 0 Q8N1G0;A6PVV7 Q8N1G0 ZNF687 Zinc finger protein 687 1 0 HGLQLGAQS(1)PGR 137.09 0.0015579 27367000 2762.2 1954 2252.3 2490.1 2965.5 2724.5 2147.3 829.52 2821.6 2308.5 TRUE FALSE FALSE 2543.568955 2122.895053 2335.772219 2479.796626 2930.138349 2159.407989 2207.547459 1082.436829 2512.077539 2388.720203 1.064824985 0.888716498 0.977834163 1.038127707 1.226656159 0.904002062 0.924154891 0.453145089 1.051641601 1 11.22202216 -4.06221699 1.65925788 1.026392511 8.37E-09 0.788070803 0.087880727 0.56085296 0.983488719 0.012325868 1.070734379 8.67E-05 4.06221699 -1.026392502 down TQDPS(ph)SPGTTPPQAR ddPTM_HeLa_Curcumin_4h_R1 1 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 0 T(0.002)QDPS(0.902)S(0.077)PGT(0.005)T(0.014)PPQAR 110.6 0.0021669 231870000 1427.6 1279.2 1389.3 1003.5 1243.5 1545.3 1062 1073.5 1790.7 1567.6 TRUE FALSE FALSE 1314.603954 1389.768348 1440.78868 999.3477829 1228.672075 1224.787361 1091.796862 1400.805208 1594.26469 1622.073983 0.810446359 0.856784809 0.888238573 0.616092603 0.757469812 0.755074906 0.67308697 0.863588975 0.982855718 1 10.66362391 -9.054590841 0.298006949 1.092439857 0.729254152 0.578762089 0.076301157 1.822038077 0.245698115 0.235504877 0.04877371 8.82E-10 9.054590841 -0.363185705 TQDPSS(ph)PGT(ph)TPPQAR ddPTM_HeLa_Curcumin_4h_R1 1 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 2 0 T(0.016)QDPS(0.376)S(0.918)PGT(0.394)T(0.296)PPQAR 101.01 0.016279 38456000 2722 2198.1 2613.3 2825.5 2919.2 3351.7 2192 1966.9 3415.1 2794 TRUE FALSE FALSE 2506.550828 2388.093969 2710.151197 2813.80883 2884.390447 2656.519639 2253.501621 2566.598756 3040.472074 2891.091292 0.866991241 0.826018181 0.937414603 0.973268758 0.997682244 0.918863976 0.779464013 0.887761228 1.051669341 1 11.49739845 -9.379471843 1.112832973 0.999807388 0.897484395 0.367163056 0.064231024 0.579357252 1.287497568 0.045593907 0.011831284 4.17E-10 9.379471843 -0.102322992 TQDPSS(ph)PGTTPPQAR ddPTM_HeLa_Curcumin_4h_R1 1 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 0 TQDPS(0.085)S(0.909)PGT(0.005)T(0.001)PPQAR 205.52 1.61E-09 243890000 5737.8 4824 5056.1 5728.2 5247.3 5731.5 5427 6302.8 5118.5 5328.2 TRUE FALSE FALSE 5283.647076 5240.965065 5243.483514 5704.498226 5184.729375 4542.722293 5579.267014 8224.494705 4557.013356 5513.354553 0.958336168 0.9505946 0.95105139 1.034669215 0.940394695 0.823948877 1.011955056 1.491740578 0.826540958 1 12.42871467 -4.267866345 4.677011103 0.966895305 1.520640833 0.849496997 0.068782676 0.03905565 2.311852013 0.007425021 0.069865997 5.40E-05 4.267866345 0.553745528 TQDPSSPGTT(ph)PPQAR ddPTM_HeLa_Curcumin_4h_R1 1 TQDPSSPGTTPPQAR 15 0 Q13112 Q13112 CHAF1B Chromatin assembly factor 1 subunit B 1 0 TQDPS(0.004)S(0.004)PGT(0.041)T(0.951)PPQAR 139 0.0016078 16603000 7381.2 5838.9 6798.1 7223.2 6472.1 8579.6 5771.5 6304.4 7932.1 6618.7 TRUE FALSE FALSE 6796.970231 6343.588498 7050.043566 7193.312312 6394.924435 6800.094248 5933.432757 8226.582538 7061.968475 6848.699332 0.992446872 0.926247188 1.029398901 1.050318019 0.933742909 0.99290302 0.866359066 1.201189034 1.031140094 1 12.74161431 TQEDEEEISTS(ph)PGVSEFVSDAFDACNLNQEDLRK ddPTM_HeLa_Curcumin_4h_R1 1 TQEDEEEISTSPGVSEFVSDAFDACNLNQEDLRK 34 1 Q96A49 Q96A49 SYAP1 Synapse-associated protein 1 1 0 TQEDEEEIS(0.102)T(0.293)S(0.413)PGVS(0.188)EFVS(0.003)DAFDACNLNQEDLRK 85.784 5.92E-08 5016700 1174.8 730.15 849.77 1165.3 821.99 1124 821.06 1131.7 885.06 824.9 TRUE FALSE FALSE 1081.81334 793.2609125 881.2632237 1160.478297 812.1883061 890.8697299 844.0967338 1476.75012 787.9711323 853.5652136 1.26740561 0.929350095 1.032449788 1.359566063 0.951524609 1.043704354 0.98890714 1.73009642 0.923152818 1 9.737357571 -4.25512001 24.69446411 1.100773366 1.730096755 0.652322174 0.144410697 303.5501757 1186156.736 0.020032205 0.249686433 5.56E-05 4.25512001 0.62932339 TQETLS(ph)QAGQK ddPTM_HeLa_Curcumin_4h_R1 2 TQETLSQAGQK 11 0 O43399;O43399-5;O43399-7;A0A087WYR3;O43399-2;O43399-4;O43399-3;O43399-6 O43399 TPD52L2 Tumor protein D54 1 0 TQET(0.013)LS(0.987)QAGQK;TQETLS(1)QAGQK ; 152 1.06E-05 13153000 2694.5 2616.3 3166.7 3225.6 2353.1 4456.1 4415.4 3558.5 3143.8 3022.4 TRUE FALSE FALSE 2481.227482 2842.441314 3284.060688 3212.253322 2325.040819 3531.854629 4539.284241 4643.470269 2798.933005 3127.428175 0.793376328 0.90887501 1.050083488 1.027122972 0.743435401 1.129315985 1.451443162 1.484756806 0.894963161 1 11.61076104 -4.893158245 3.12768489 0.912600728 1.478271961 0.846600821 0.092952482 0.074576909 1.43351624 0.015315602 0.055364373 1.28E-05 4.893158245 0.565671233 TQETLSQAGQK ddPTM_HeLa_Curcumin_4h_R1 1 TQETLSQAGQK 11 0 O43399;O43399-5;O43399-7;A0A087WYR3;O43399-2;O43399-4;O43399-3;O43399-6 O43399 TPD52L2 Tumor protein D54 0 0 181.68 1.04E-11 1490300 1490 1195.5 1126.1 1347.7 1185.1 1392.3 927.7 1102.7 1434.8 1236.2 FALSE FALSE TRUE 1372.064928 1298.833693 1167.834257 1342.123574 1170.968457 1103.521286 953.7287652 1438.908154 1277.40603 1279.157858 1.072631434 1.015381866 0.912971178 1.049224352 0.915421384 0.862693591 0.74559114 1.124887085 0.998630483 1 10.3209786 -6.015143879 1.133944732 1.03112659 0.896016401 0.13894972 0.09850181 0.488397134 1.24061422 0.015703005 0.037164265 9.66E-07 6.015143879 -0.135110188 TQFVSPWKEGDELEDNGKNFY(ph)ESDDDQKEK ddPTM_HeLa_Curcumin_4h_R1 1 TQFVSPWKEGDELEDNGKNFYESDDDQKEK 30 3 O00203-3;O00203 O00203-3 AP3B1 AP-3 complex subunit beta-1 1 0 TQFVS(0.002)PWKEGDELEDNGKNFY(0.925)ES(0.073)DDDQKEK 60.993 0.00045069 50747000 1557.2 1085.3 1281.8 1418.4 902.08 1375.6 927.59 892.02 1420.9 1334.5 TRUE FALSE FALSE 1433.945977 1179.108496 1329.304636 1412.531037 891.3232852 1090.285054 953.6156789 1163.992792 1265.030825 1380.873776 1.038433782 0.853885791 0.962654704 1.022925528 0.645477741 0.789561706 0.690588594 0.842939313 0.91610895 1 10.43136573 -5.771663414 24.99766667 1.000557239 0.741846595 0.666185808 0.075117757 71.44896957 174692.2779 0.010325462 0.018869812 1.69E-06 5.771663414 -0.258710644 TQKPNPAVPPPLSSS(ph)PLYSR ddPTM_HeLa_Curcumin_4h_R1 1 TQKPNPAVPPPLSSSPLYSR 20 1 H7C1T0;H0Y770;A0A2R8Y5T1;A0A2R8Y842;A0A2R8YEW8;A0A5F9UWT1;A0A2R8Y5K9;A0A2R8Y721;A0A2R8Y6V4;A0A2R8Y6H3;A0A2R8Y7U0;O75140-9;O75140-4;O75140-8;O75140-1;O75140-5;O75140-6;O75140 H7C1T0 DEPDC5 DEP domain-containing protein 5 1 0 TQKPNPAVPPPLS(0.271)S(0.271)S(0.417)PLYS(0.04)R 86.508 0.00075677 13234000 2753.8 2105.3 2324 2360.6 2257.6 2844.9 1688.8 1410.3 2347.7 2314.2 TRUE FALSE FALSE 2535.833824 2287.272751 2410.129484 2350.832463 2230.679594 2254.835671 1736.183183 1840.293978 2090.163184 2394.618278 1.058972049 0.955172176 1.006477528 0.981714908 0.931538699 0.941626351 0.725035468 0.768512458 0.872858611 1 11.22557998 -4.84437449 0.837420917 1.021890089 0.675370427 0.614575094 0.062652561 0.313715623 0.26308128 0.006851933 0.083096312 1.43E-05 4.84437449 -0.346519662 S(ph)LNLEDYK ddPTM_HeLa_Curcumin_4h_R1 1 SLNLEDYK 8 0 Q92541 Q92541 RTF1 RNA polymerase-associated protein RTF1 homolog 1 0 S(0.997)LNLEDY(0.003)K 109.72 0.011377 11779000 5754.7 4528.5 5399.9 5277.9 5113 8876.3 7595 10016 6528.7 4575.9 TRUE FALSE FALSE 5299.209423 4919.923361 5600.025044 5256.061448 5052.030814 7035.255323 7808.095259 13069.83229 5812.517944 4734.912184 1.119177973 1.039073835 1.182709378 1.110065244 1.066974554 1.485825935 1.649047534 2.760311445 1.227587275 1 12.20912195 -1.188979595 0.734020211 1.058920011 199.9999999 0.965815081 0.093328564 22.70503684 0.134140986 0.012620073 7408.665636 0.064717302 1.188979595 198.9410799 up ST(ph)SPAGQHHSPISS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 STSPAGQHHSPISSR 15 0 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 2 0 S(0.414)T(0.549)S(0.037)PAGQHHS(0.008)PIS(0.018)S(0.974)R 99.011 0.0038028 0 709.28 553.19 480.25 480.1 813.12 884.24 712.67 957.76 786.43 499.31 TRUE FALSE FALSE 653.1397396 601.0052786 498.0484875 478.1134734 803.4240751 700.8386566 732.6656021 1249.776615 700.1605966 516.6609853 1.264155332 1.163248814 0.963975414 0.925391092 1.555031438 1.356476832 1.418078049 2.41894908 1.355164443 1 9.013074135 -1.179139363 0.778817204 1.119896971 200 0.799162362 0.183840242 93.43023125 0.459828739 0.028831856 32557.67795 0.066200404 1.179139363 198.880103 up TQLEELEDELQATEDAK ddPTM_HeLa_Curcumin_4h_R1 4 TQLEELEDELQATEDAK 17 0 P35579;P35579-2;P35580;P35580-5;P35580-2;P35580-3;P35580-4;P35749-4;P35749-3;P35749;P35749-2 P35579;P35580;P35749-4 MYH9;MYH10;MYH11 Myosin-9;Myosin-10;Myosin-11 0 0 ;;; ;;; 281.93 5.94E-65 46172900 7861.2 6644.59 7429.99 7377.49 8390.59 7812.2 7394.57 6415.24 7275.33 6610.75 FALSE FALSE TRUE 7238.977725 7218.918752 7705.351965 7346.963901 8290.537694 6191.861658 7602.041733 8371.217144 6477.244501 6840.47307 1.058256885 1.05532449 1.126435538 1.074043246 1.211983091 0.905180328 1.111332748 1.223777516 0.94690008 1 12.73988039 -1.05010507 0.014161587 7.63E-07 2.365191699 0.280873346 0.083205327 6132.897143 6.830180382 463.748258 699.9966527 0.089103534 1.05010507 2.365190935 TQLTS(ph)MLMMNLESR ddPTM_HeLa_Curcumin_4h_R1 1 TQLTSMLMMNLESR 14 0 Q5SXN9;Q10713-2;Q10713 Q5SXN9 PMPCA Mitochondrial-processing peptidase subunit alpha 1 0 T(0.021)QLT(0.086)S(0.892)MLMMNLES(0.001)R 50.102 0.017617 8975700 1234.8 1213.4 1307 1028.5 1092.7 1333.2 911.11 1796.5 1391.8 1319.2 TRUE FALSE FALSE 1137.064277 1318.280889 1355.43857 1024.24434 1079.670266 1056.679292 936.6732945 2344.24458 1239.123022 1365.042102 0.83298843 0.965743758 0.992964662 0.75033901 0.790942832 0.774100147 0.686186377 1.717342327 0.907754435 1 10.41472973 -4.252885649 24.8632239 0.885811874 1.717342781 0.85287306 0.106707306 327.073463 950685.6604 0.016769637 0.261699596 5.59E-05 4.252885649 0.831530906 TQLWAS(ph)EPGTPPLPTSLPSQNPILK ddPTM_HeLa_Curcumin_4h_R1 1 TQLWASEPGTPPLPTSLPSQNPILK 25 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;H7C3A1 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 0 T(0.003)QLWAS(0.711)EPGT(0.286)PPLPTSLPSQNPILK 161.04 1.06E-09 281360000 5283.5 4557.1 4928 4301.8 4892.4 6292.2 4867.2 4509.5 5092 4516.1 TRUE FALSE FALSE 4865.3054 4950.995418 5110.636015 4284.000291 4834.061325 4987.126792 5003.760533 5884.425791 4533.42034 4673.034139 1.041144844 1.059481971 1.093644057 0.916749196 1.034458808 1.067213858 1.070773374 1.259230217 0.970123523 1 12.19014386 -3.625755022 1.187806417 1.022535886 1.921530848 0.692132271 0.047549569 2.376682641 0.944744732 0.006577469 3.82545547 0.000236725 3.625755022 0.898994962 TQLWASEPGT(ph)PPLPTSLPSQNPILK ddPTM_HeLa_Curcumin_4h_R1 1 TQLWASEPGTPPLPTSLPSQNPILK 25 0 Q9BXP5-5;Q9BXP5-4;Q9BXP5-2;Q9BXP5-3;Q9BXP5;H7C3A1 Q9BXP5-5 SRRT Serrate RNA effector molecule homolog 1 0 TQLWAS(0.02)EPGT(0.977)PPLPT(0.002)SLPSQNPILK 95.141 1.19E-05 226520000 11232 7933.1 10046 9212 9758.9 13456 10302 10828 10765 9125.4 TRUE FALSE FALSE 10342.97535 8618.801815 10418.3136 9173.883185 9642.531491 10665.07392 10591.04639 14129.40735 9584.106433 9442.506971 1.095363274 0.912766264 1.103341902 0.971551645 1.021183413 1.129474826 1.121635009 1.496361866 1.014995961 1 13.20495423 -3.217012336 1.092161367 1.034376626 4.824634487 0.848880581 0.059171389 3.850459311 0.630562684 0.008956581 28.69600571 0.000606719 3.217012336 3.790257861 TQMAEVLPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 TQMAEVLPSPR 11 0 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 TQMAEVLPS(1)PR;TQMAEVLPS(1)PR ; 143.55 0.0013022 116667000 8893.8 5496.2 7181.5 9173.4 7698.7 11186.9 9274.9 3573.6 9980.7 7951.7 TRUE FALSE FALSE 8189.846345 5971.267037 7447.652707 9135.442901 7606.898031 8866.610838 9535.128732 4663.174189 8885.84218 8228.020983 0.995360411 0.72572336 0.905157233 1.110284347 0.924511258 1.077611598 1.158860527 0.566743109 1.079948896 1 13.00632976 -3.753022689 0.010057354 1.861959557 1.09E-06 0.046384544 0.171016951 25976.06525 35.67349281 3035.287695 3588.661436 0.000176595 3.753022689 -1.861958463 TQNVLGEK ddPTM_HeLa_Curcumin_4h_R1 2 TQNVLGEK 8 0 E9PL09;P23396;P23396-2;E9PPU1;E9PQ96;E9PJH4;F2Z2S8;E9PK82;H0YCJ7;H0YF32 E9PL09 RPS3 40S ribosomal protein S3 0 0 ; ; 108.98 0.0070699 15673400 6804.4 5395.3 6159.7 5829.5 5722.6 6469.4 5599.6 5433.2 5978.1 6042 FALSE FALSE TRUE 6265.82456 5861.645691 6387.983901 5805.379074 5654.361733 5127.573515 5756.709705 7089.757669 5322.317386 6251.95905 1.002217786 0.937569431 1.021757156 0.928569593 0.90441439 0.820154686 0.920784935 1.134005775 0.851303942 1 12.61009261 -6.248295916 23.22884657 0.996715212 0.931618998 0 0.0891977 458.5290308 810370.1053 0.011245552 0.018561192 5.65E-07 6.248295916 -0.065096214 TQPDGTSVPGEPAS(ph)PISQR ddPTM_HeLa_Curcumin_4h_R1 6 TQPDGTSVPGEPASPISQR 19 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 TQPDGTSVPGEPAS(1)PISQR;TQPDGTSVPGEPAS(1)PISQR;TQPDGTSVPGEPAS(1)PISQR;TQPDGTSVPGEPAS(0.997)PIS(0.003)QR;TQPDGTSVPGEPAS(0.999)PIS(0.001)QR;TQPDGTSVPGEPAS(0.999)PIS(0.001)QR ;;;;; 325.1 7.51E-134 2945184000 17092.4 13834.5 15651.7 15119.4 15913.5 20073.8 17500.3 14445.8 16402.8 14963.7 TRUE FALSE FALSE 15739.5185 15030.29253 16231.76577 15056.83993 15723.74191 15910.2676 17991.31132 18850.25792 14603.45388 15483.68746 1.016522617 0.970717897 1.048313963 0.972432437 1.0155037 1.027550294 1.161952627 1.217426919 0.943150907 1 13.91846147 -4.699030244 2.544500666 1.005964461 1.214140328 0.875720708 0.029071319 0.04793229 0.589490522 0.002725097 0.014345025 2.00E-05 4.699030244 0.208175867 TQPDGTSVPGEPAS(ph)PISQRLPPK ddPTM_HeLa_Curcumin_4h_R1 1 TQPDGTSVPGEPASPISQRLPPK 23 1 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 TQPDGTSVPGEPAS(0.982)PIS(0.017)QRLPPK 109.98 6.40E-06 10404000 3754.3 2434.9 2548.8 2717 1784.7 3561 2723.6 3022.9 4881.8 4332.5 TRUE FALSE FALSE 3457.143193 2645.361906 2643.26077 2705.757774 1763.418618 2822.408459 2800.016886 3944.568294 4346.278754 4483.054053 0.771158044 0.590080306 0.589611622 0.603552342 0.393352076 0.629572703 0.624577989 0.87988417 0.969490598 1 12.13026618 -8.007853823 0.797559262 0.965637544 0.60342054 0.604442928 0.115634052 0.261634103 0.362633323 0.039226626 0.028704298 9.82E-09 8.007853823 -0.362217004 TQPSSGVDSAVGTLPAT(ph)SPQSTSVQAK ddPTM_HeLa_Curcumin_4h_R1 3 TQPSSGVDSAVGTLPATSPQSTSVQAK 27 0 Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 Q13428 TCOF1 Treacle protein 1 0 TQPSSGVDSAVGT(0.036)LPAT(0.414)S(0.414)PQS(0.045)T(0.067)S(0.024)VQAK;TQPSSGVDSAVGTLPAT(0.495)S(0.495)PQS(0.003)T(0.005)S(0.002)VQAK;TQPSSGVDS(0.022)AVGT(0.098)LPAT(0.652)S(0.227)PQS(0.001)TSVQAK ;; 142.45 3.62E-08 50927000 7183.3 6047 6286.4 6288.7 6756.4 8082.2 5455.97 3590.83 7360.3 6869.1 TRUE FALSE FALSE 6614.734225 6569.675735 6519.379514 6262.679026 6675.834343 6405.860615 5609.049834 4685.657537 6552.893505 7107.800714 0.930630232 0.92429093 0.91721473 0.881099411 0.939226437 0.9012437 0.789139997 0.659227478 0.92192983 1 12.79518752 -3.336062742 0.557734756 0.961686435 2.13E-30 0.868350174 0.032979128 2.37535627 0.236609691 0.007114437 1.876936202 0.000461251 3.336062742 -0.961686435 TQQLHPVLQKPSVFGNDS(ph)DDDDETSVSESLQR ddPTM_HeLa_Curcumin_4h_R1 1 TQQLHPVLQKPSVFGNDSDDDDETSVSESLQR 32 1 Q9H0G5 Q9H0G5 NSRP1 Nuclear speckle splicing regulatory protein 1 1 0 TQQLHPVLQKPS(0.011)VFGNDS(0.989)DDDDETSVSESLQR 105.75 1.63E-11 58272000 2254.6 2052.3 2271 2096.7 3195.4 2690.4 2361.5 2120.8 2237.3 2129.5 TRUE FALSE FALSE 2076.146031 2229.691667 2355.165258 2088.024411 3157.296942 2132.380713 2427.757334 2767.422157 1991.873787 2203.499966 0.942203795 1.011886408 1.068829269 0.947594483 1.432855453 0.967724414 1.101773257 1.255921125 0.903959073 1 11.10558116 TQQS(ph)PISNGS(ph)PELGIK ddPTM_HeLa_Curcumin_4h_R1 1 TQQSPISNGSPELGIK 16 0 Q15723-2;Q15723-3;Q15723-1;Q15723 Q15723-2 ELF2 ETS-related transcription factor Elf-2 2 0 T(0.058)QQS(0.936)PIS(0.127)NGS(0.879)PELGIK 105.06 0.0047769 4814600 2057.7 1764.8 1635.4 1778.1 1782.5 2182.8 1414.3 735.75 2274.8 1700.7 TRUE FALSE FALSE 1894.830874 1917.341448 1696.009363 1770.742693 1761.244852 1730.062675 1453.981452 960.076788 2025.260131 1759.799198 1.076731297 1.089522856 0.963751639 1.006218604 1.000821488 0.98310232 0.82622009 0.545560419 1.150847286 1 10.7811951 -3.960075309 1.049729388 1.034096714 6.14E-17 0.902093926 0.050671327 0.531765228 0.302733659 0.006244134 0.711793901 0.000109629 3.960075309 -1.034096714 TQRLS(ph)AETWDLLR ddPTM_HeLa_Curcumin_4h_R1 1 TQRLSAETWDLLR 13 1 A0A0A0MSK4;A0A0A0MRC4;Q86YR5-4;Q86YR5 A0A0A0MSK4 GPSM1 G-protein-signaling modulator 1 1 0 T(0.02)QRLS(0.979)AET(0.001)WDLLR 101.3 0.0027862 2662800 1431.5 1037.7 890.33 955.31 1169.4 1281.3 925.21 523.02 886.71 921.14 TRUE FALSE FALSE 1318.195264 1127.394164 923.326413 951.3571803 1155.455669 1015.543937 951.1689025 682.4863903 789.4401314 953.1495464 1.382988923 1.182809317 0.968710961 0.998119533 1.212250138 1.065461281 0.997922001 0.716032854 0.828243726 1 9.896558776 -3.717062907 0.839810246 1.161739418 4.03E-13 0.225845368 0.159381375 4.054261503 1.111779077 0.026116963 5.421376921 0.000191839 3.717062907 -1.161739418 TQS(ph)APLPQNAQALQHLVIQQQHQQFLEK ddPTM_HeLa_Curcumin_4h_R1 1 TQSAPLPQNAQALQHLVIQQQHQQFLEK 28 0 P56524-2;P56524 P56524-2 HDAC4 Histone deacetylase 4 1 0 T(0.396)QS(0.604)APLPQNAQALQHLVIQQQHQQFLEK 49.038 0.0072324 30067000 811.91 1018.9 1078.2 1041.4 1172.9 1130.2 846.36 645.78 1191.9 1227.6 TRUE FALSE FALSE 747.6464668 1106.969176 1118.15904 1037.090963 1158.913934 895.78378 870.1065837 842.6753492 1061.151552 1270.259009 0.588577969 0.871451545 0.880260666 0.816440549 0.912344589 0.705197738 0.684983596 0.663388603 0.835382032 1 10.31090698 -9.614440184 1.429726143 0.99965626 0.747940552 0.164647589 0.112345704 0.349709117 1.286223102 0.083413148 0.019268588 2.43E-10 9.614440184 -0.251715708 TQS(ph)PEFEAQSSK ddPTM_HeLa_Curcumin_4h_R1 1 TQSPEFEAQSSK 12 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 0 T(0.095)QS(0.904)PEFEAQS(0.001)SK 184.02 5.66E-05 20675000 1786.7 1608.7 1979 2271.9 2244.6 2435.3 2046.2 1568.6 2131.8 1746 TRUE FALSE FALSE 1645.28081 1747.74886 2052.343481 2262.49948 2217.834611 1930.191329 2103.610865 2046.858919 1897.946874 1806.67337 0.910668656 0.967385078 1.135979262 1.252301339 1.227579178 1.06836762 1.164355937 1.132943538 1.050520202 1 10.81911999 -6.733679792 4.436256265 0.956731304 1.168611109 0.689876366 0.058953149 0.073505666 3.318110619 0.009290289 0.012973292 1.85E-07 6.733679792 0.211879805 TQS(ph)PGGCSAEAVLAR ddPTM_HeLa_Curcumin_4h_R1 2 TQSPGGCSAEAVLAR 15 0 K7ESM2;K7ELS4;K7EJA3;K7ERG7;Q96MH2 K7ESM2 HEXIM2 Protein HEXIM2 1 0 T(0.388)QS(0.611)PGGCSAEAVLAR;T(0.016)QS(0.983)PGGCSAEAVLAR ; 118.55 0.0014327 204334000 4323.9 3505.1 3608.8 4469.5 3689.6 4075.6 3692.8 1632.97 3856.5 4173.8 TRUE FALSE FALSE 3981.658752 3808.065226 3742.545303 4451.006393 3645.60393 3230.274619 3796.410029 2130.855036 3433.451598 4318.839239 0.921927984 0.881733497 0.866562772 1.030602471 0.844116608 0.747949724 0.87903481 0.493386051 0.794994073 1 12.0764279 -3.6845434 0.611715021 0.955176889 2.16E-25 0.567037763 0.093728609 2.476951874 0.386909374 0.013736544 1.95531766 0.000206755 3.6845434 -0.955176889 TQSAS(ph)PPPK ddPTM_HeLa_Curcumin_4h_R1 1 TQSASPPPK 9 0 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 0 TQS(0.002)AS(0.998)PPPK 89.403 0.020212 16596000 3971.7 4558 4250.2 3586 4417.4 3938.7 3236.7 3169.8 3825 3316.7 TRUE FALSE FALSE 3657.335754 4951.97321 4407.716151 3571.162082 4364.72539 3121.769222 3327.513091 4136.257428 3405.40707 3431.955078 1.06567122 1.442901523 1.284316388 1.040562012 1.271789779 0.909618323 0.969567787 1.205218989 0.992264465 1 11.74481495 -7.502439996 19.01567864 1.028970545 1.155583712 0.159442629 0.150202748 19.06784329 17743.03131 0.027415772 0.029499133 3.14E-08 7.502439996 0.126613166 TQSAS(ph)PPPKER ddPTM_HeLa_Curcumin_4h_R1 2 TQSASPPPKER 11 1 Q9UN81 Q9UN81 L1RE1 LINE-1 retrotransposable element ORF1 protein 1 0 TQS(0.008)AS(0.992)PPPKER;T(0.009)QS(0.007)AS(0.984)PPPKER ; 68.277 0.018462 185595000 8078.9 6912.1 7510.7 6833.8 7089.3 8851.4 7144.7 6403 8697.9 7487.5 TRUE FALSE FALSE 7439.44654 7509.551124 7789.053149 6805.523546 7004.764728 7015.519864 7345.161053 8355.245224 7743.762131 7747.690068 0.960214783 0.969263233 1.005338763 0.878393881 0.904110085 0.905498259 0.948045287 1.078417587 0.999493018 1 12.91955053 -6.306656189 24.99681701 0.981293983 0.938947018 0.143837519 0.052328083 683.6393033 377929.071 0.008099135 0.012371659 4.94E-07 6.306656189 -0.042346965 DLESCSDDDNQGS(ph)KSPK ddPTM_HeLa_Curcumin_4h_R1 1 DLESCSDDDNQGSKSPK 17 1 F8W895;A0A0A0MRK1;Q5T3I0;E9PAV9;Q5T3I0-3 F8W895 GPATCH4 G patch domain-containing protein 4 1 0 DLESCSDDDNQGS(0.518)KS(0.481)PK 58.658 0.016331 21491000 1825.6 1727 1530.7 1844.5 2185.1 2527.5 2135.7 2937.4 1798.3 1529.4 TRUE FALSE FALSE 1681.101834 1876.274185 1587.429089 1836.867948 2159.04411 2003.268009 2195.621994 3832.999738 1601.030989 1582.546536 1.062276398 1.18560443 1.00308525 1.160703907 1.364284753 1.265850933 1.38739806 2.422045514 1.011680196 1 10.62803221 -1.147939644 0.763446397 1.055532637 199.9999984 0.927502421 0.108383691 52.75554151 0.260860864 0.01774422 18010.74228 0.071131236 1.147939644 198.9444657 up TQSLS(ph)ALPK ddPTM_HeLa_Curcumin_4h_R1 2 TQSLSALPK 9 0 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 0 T(0.008)QS(0.321)LS(0.671)ALPK;T(0.084)QS(0.128)LS(0.787)ALPK ; 110.54 0.0089755 114408000 18251.7 15360.6 16995.4 16730.8 17057.4 21325.5 20846.7 16955.9 18781.8 18805.7 TRUE FALSE FALSE 16807.05869 16688.30182 17625.26447 16661.57238 16854.00165 16902.35091 21431.6023 22125.67585 16721.48353 19459.19668 0.863707735 0.857604869 0.905754989 0.856231255 0.866120114 0.868604763 1.101361102 1.137029253 0.859310063 1 14.24816453 -4.712868029 6.724861713 0.912448773 1.123325147 0.775744509 0.04866662 0.098519859 10.13393204 0.009057811 0.034060333 1.94E-05 4.712868029 0.210876374 TQSRPGGPPNPPGPS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 TQSRPGGPPNPPGPSPK 17 1 B9EGQ5;A0A669KBG4;M0QXA7;A0A669KBH9;A0A2R8YFV2;A0A669KAV7;O95785-4;O95785-3;O95785;O95785-2 B9EGQ5 WIZ Protein Wiz 1 0 TQSRPGGPPNPPGPS(1)PK;TQSRPGGPPNPPGPS(1)PK ; 64.761 0.011525 31918000 4586.4 4376 4147.6 4764.1 4591.4 5809.1 5400 2916.85 5726.6 4949.1 TRUE FALSE FALSE 4223.3816 4754.241941 4301.313705 4744.387417 4536.650554 4604.227178 5551.509467 3806.184137 5098.406307 5121.080857 0.82470512 0.928366896 0.839923021 0.926442591 0.885877548 0.899073322 1.084050344 0.743238438 0.995572312 1 12.32223262 -9.580894335 1.377176539 0.999779555 0.888708885 0.206871986 0.083041882 0.538435968 1.837021741 0.054879978 0.012914054 2.62E-10 9.580894335 -0.11107067 TQSSLT(ph)VSEVLTR ddPTM_HeLa_Curcumin_4h_R1 2 TQSSLTVSEVLTR 13 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 T(0.008)QS(0.013)S(0.013)LT(0.966)VSEVLTR;T(0.003)QS(0.028)S(0.028)LT(0.867)VS(0.074)EVLTR ; 199.33 3.17E-06 131413000 2192.26 2061.42 1920.16 2557.3 2487.2 3386.3 2325.4 665.66 2185.8 1908.99 TRUE FALSE FALSE 2018.740308 2239.599959 1991.322819 2546.71857 2457.541764 2683.943209 2390.644466 868.6166697 1946.023209 1975.32726 1.021977648 1.133786793 1.008097675 1.289264124 1.244118792 1.358733442 1.210252353 0.439733044 0.985164964 1 10.94787597 -7.248533034 1.574466572 1.007101734 1.126560572 0.02125311 0.242526663 0.997104667 4.699001956 0.044952431 0.053608573 5.64E-08 7.248533034 0.119458838 TQSSS(ph)CEDLPSTTQPK ddPTM_HeLa_Curcumin_4h_R1 2 TQSSSCEDLPSTTQPK 16 0 Q5JS72;O14936-5;A0A2U3TZM4;O14936-3;O14936-4;A0A2R8Y6F8;A0A2R8YFN5 Q5JS72 CASK 1 0 TQSS(0.066)S(0.932)CEDLPS(0.001)TTQPK;TQSS(0.017)S(0.981)CEDLPS(0.001)TTQPK ; 223.29 7.38E-16 57433000 5031.2 4254.9 4435.7 5025.4 4594.2 5402.3 3519.3 2802.2 5495.9 4080.7 TRUE FALSE FALSE 4632.975211 4622.674597 4600.090944 5004.606226 4539.417166 4281.802084 3618.042086 3656.57788 4893.01352 4222.504021 1.097210373 1.094770916 1.089422513 1.185222371 1.075053367 1.014043341 0.856847517 0.865973807 1.158794283 1 12.04388308 -4.849947471 3.377054503 1.065946322 0.857433169 0.730089714 0.054762907 0.105631963 2.342398227 0.008385692 0.030498765 1.41E-05 4.849947471 -0.208513153 SDS(ph)PVPTAPTSGGPKPSTASAVPELATDPELEKK ddPTM_HeLa_Curcumin_4h_R1 1 SDSPVPTAPTSGGPKPSTASAVPELATDPELEKK 34 2 Q86U44;B4E349;F5H6D8;B4DTN4 Q86U44 METTL3 N6-adenosine-methyltransferase 70 kDa subunit 1 0 S(0.16)DS(0.719)PVPT(0.022)APT(0.02)S(0.02)GGPKPS(0.019)T(0.019)AS(0.019)AVPELATDPELEKK 53.499 0.00060363 19127000 2905.8 2058 2734.4 2589 2488.6 2706.5 2160.2 817.05 2846.6 2312.9 TRUE FALSE FALSE 2675.802864 2235.88435 2835.739269 2578.287404 2458.92507 2145.141391 2220.809398 1066.164784 2534.335102 2393.273103 1.118051618 0.934237028 1.184879096 1.077305971 1.027431875 0.896321188 0.927938143 0.445483962 1.058941037 1 11.22476932 -4.061016073 1.253118235 1.054924298 9.33E-14 0.845289921 0.076191077 0.617616252 0.590336038 0.011394215 0.941758784 8.69E-05 4.061016073 -1.054924298 down IS(ph)LPLPNFSSLNLR ddPTM_HeLa_Curcumin_4h_R1 1 ISLPLPNFSSLNLR 14 0 P08670;B0YJC4 P08670 VIM Vimentin 1 0 IS(0.695)LPLPNFS(0.238)S(0.068)LNLR 114.21 0.0023322 308870000 600.55 700.02 759.67 745.62 825.41 1531.4 1073.3 1669.3 799.48 865.64 TRUE FALSE FALSE 553.0158338 760.5266096 787.8240385 742.534822 815.5675248 1213.770378 1103.413909 2178.261885 711.7790442 895.7209256 0.617397471 0.849066476 0.879541848 0.8289801 0.910515208 1.355076501 1.231872426 2.431853296 0.79464376 1 9.8069055 -1.10221752 0.725069941 0.82107051 200 0.917100056 0.141415285 59.54650774 0.315307425 0.027820366 19256.74925 0.079028271 1.10221752 199.1789295 up GWLRDPS(ph)ASPGDAGEQAIR ddPTM_HeLa_Curcumin_4h_R1 1 GWLRDPSASPGDAGEQAIR 19 1 P18206;P18206-2 P18206 VCL Vinculin 1 0 GWLRDPS(0.594)AS(0.406)PGDAGEQAIR 127.96 5.95E-05 32002000 1837 1530.7 1790.5 1593.3 2385.9 2917.1 2405 2440.4 1683.4 1531.7 TRUE FALSE FALSE 1691.599512 1663.006887 1856.857505 1586.707347 2357.449701 2312.060578 2472.477827 3184.466726 1498.735232 1584.926461 1.067304732 1.049264384 1.171573288 1.001123639 1.487418981 1.458780981 1.559995298 2.009220493 0.945618152 1 10.63020019 -1.101160586 0.364270579 1.007504736 12.9942624 0.910930252 0.097309542 9.345073972 0.124197308 0.024394832 78.16300295 0.079220835 1.101160586 11.98675766 up TQT(ph)PPVSPAPQPT(ph)EERLPSSPVYEDAASFK ddPTM_HeLa_Curcumin_4h_R1 1 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 2 0 T(0.128)QT(0.659)PPVS(0.168)PAPQPT(0.593)EERLPS(0.142)S(0.292)PVY(0.017)EDAASFK 67.279 0.00012796 89184000 4425 3551.1 4027.3 3651.2 3246.8 4294.1 4406.3 5313 4808.1 3905.7 TRUE FALSE FALSE 4074.756581 3858.041261 4176.555281 3636.092302 3208.084031 3403.455256 4529.928919 6932.909242 4280.663459 4041.422784 1.008248035 0.954624514 1.033436862 0.899705994 0.793800649 0.842142839 1.120874791 1.715462502 1.059197141 1 11.98064757 -4.290037673 3.249927749 0.971492343 1.796915102 0.883141158 0.08320761 0.076203923 1.302472548 0.012290191 0.151582865 5.13E-05 4.290037673 0.825422758 TQT(ph)PPVSPAPQPTEER ddPTM_HeLa_Curcumin_4h_R1 3 TQTPPVSPAPQPTEER 16 0 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 1 0 T(0.018)QT(0.982)PPVSPAPQPTEER;T(0.018)QT(0.967)PPVS(0.013)PAPQPT(0.002)EER;TQT(1)PPVSPAPQPTEER ;; 138.81 0.0011707 398392400 7259.2 6961.9 7451.3 6769.6 8576.5 8568.3 8191.8 4687.3 6874.2 6261.5 TRUE FALSE FALSE 6684.62666 7563.655614 7727.451733 6741.589189 8474.230839 6791.137995 8421.639861 6116.436192 6120.117458 6479.086659 1.031723607 1.167395346 1.192676088 1.04051536 1.307936023 1.048162859 1.299818987 0.944027533 0.944595709 1 12.66157474 -7.327649851 4.68167077 1.013928576 1.149672929 0.278849146 0.109283115 0.198001467 8.534359755 0.016186449 0.018541652 4.70E-08 7.327649851 0.135744353 TQTESS(ph)TPPGIPGGSR ddPTM_HeLa_Curcumin_4h_R1 2 TQTESSTPPGIPGGSR 16 0 E9PER6;Q6A1A2;O15530-4;O15530-5;O15530;H3BQ10;O15530-3 E9PER6 PDPK1;PDPK2P Putative 3-phosphoinositide-dependent protein kinase 2;3-phosphoinositide-dependent protein kinase 1 1 0 TQTES(0.005)S(0.498)T(0.498)PPGIPGGSR;TQTES(0.046)S(0.477)T(0.477)PPGIPGGSR ; 242.9 3.31E-30 52735000 7703.5 6182.7 6401.6 7158.3 7534.1 10286.4 8555.8 5152.4 7638.5 5819.5 TRUE FALSE FALSE 7093.759846 6717.105038 6638.848927 7128.680851 7444.260778 8152.884688 8795.852721 6723.343041 6800.575661 6021.727192 1.178027436 1.115478138 1.102482513 1.183826604 1.236233483 1.353911333 1.460686019 1.116514054 1.129339713 1 12.55596163 -6.217372627 0.086516549 0.722215227 1.698473388 0.355757315 0.101779437 16.40749166 0.575224722 2.500721386 3.895886806 6.06E-07 6.217372627 0.976258161 TQTGDSS(ph)SISSFSYR ddPTM_HeLa_Curcumin_4h_R1 2 TQTGDSSSISSFSYR 15 0 A0A087WXA6;A0A087WT45;Q4V328-4;Q4V328;Q4V328-2;Q4V328-3 A0A087WXA6;Q4V328-3 GRIPAP1 GRIP1-associated protein 1 1 0 TQTGDSS(0.498)S(0.498)IS(0.003)SFSYR;TQTGDS(0.002)S(0.497)S(0.497)IS(0.004)SFSYR ; 235.78 1.56E-21 82862000 5296.9 4420.9 4738.8 5373.2 5032.3 6384.7 5238.1 2769.2 5582.9 4938.6 TRUE FALSE FALSE 4877.644776 4803.022897 4914.424097 5350.967122 4972.293109 5060.44125 5385.066988 3613.516332 4970.469838 5110.215982 0.954488967 0.939886477 0.961686182 1.047111735 0.973010363 0.990259759 1.053784616 0.707116166 0.972653574 1 12.31916855 -4.252340336 24.97491475 0.983166222 0.707116021 0.847157264 0.035749487 343.1233817 941779.8459 0.005058008 0.082896283 5.59E-05 4.252340336 -0.276050201 GEGDIHENVDTDLPGSLGQS(ph)EEKPVPAAPVPSPVAPAPVPSR ddPTM_HeLa_Curcumin_4h_R1 3 GEGDIHENVDTDLPGSLGQSEEKPVPAAPVPSPVAPAPVPSR 42 1 Q9UK76;Q9UK76-3 Q9UK76;Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 1 0 GEGDIHENVDT(0.001)DLPGS(0.227)LGQS(0.771)EEKPVPAAPVPS(0.002)PVAPAPVPSR;GEGDIHENVDT(0.009)DLPGS(0.223)LGQS(0.762)EEKPVPAAPVPS(0.006)PVAPAPVPSR;GEGDIHENVDT(0.094)DLPGS(0.227)LGQS(0.677)EEKPVPAAPVPS(0.002)PVAPAPVPSR ;; 88.149 6.19E-11 235940000 7615.1 7040.6 7957.7 7757.6 9989.1 10504.4 9587.2 13591.3 6425.8 6343.7 TRUE FALSE FALSE 7012.3568 7649.158092 8252.619362 7725.501107 9869.986507 8325.669031 9856.191029 17735.2248 5720.905817 6564.143103 1.068282134 1.165294231 1.257227217 1.176924541 1.503621471 1.268355808 1.501519829 2.701833968 0.871538863 1 12.68039098 -1.09389723 0.724529219 1.07569223 199.9999999 0.899076615 0.15511738 53.61858747 0.280950341 0.024487108 17308.31407 0.080556905 1.09389723 198.9243076 up TQTPPVS(ph)PAPQPTEER ddPTM_HeLa_Curcumin_4h_R1 2 TQTPPVSPAPQPTEER 16 0 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 1 0 TQT(0.035)PPVS(0.866)PAPQPT(0.098)EER;TQT(0.001)PPVS(0.999)PAPQPTEER ; 179.66 1.69E-05 29651000 4783.9 4357.2 4865.1 4407.2 5066.6 5185.5 3877.7 13590.2 4407.8 4176.6 TRUE FALSE FALSE 4405.249267 4733.816953 5045.404886 4388.964174 5006.184104 4109.968847 3986.497826 17733.78942 3924.275368 4321.736539 1.019323882 1.095350656 1.167448511 1.0155557 1.158373274 0.950999398 0.922429627 4.103394378 0.908032068 1 12.07739541 -4.260248957 24.99999169 1.027767124 4.103395364 0.991453496 0.085705159 5.547044279 116478.9064 0.010725495 0.088636487 5.49E-05 4.260248957 3.07562824 TQTPPVS(ph)PAPQPTEERLPSSPVY(ph)EDAASFK ddPTM_HeLa_Curcumin_4h_R1 1 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 2 0 T(0.189)QT(0.161)PPVS(0.653)PAPQPT(0.264)EERLPS(0.222)S(0.222)PVY(0.289)EDAASFK 49.888 0.0046323 14508000 2261.5 1926.2 2185.4 2311.2 1768.2 2572.7 2385.2 2778.4 2635.6 2382.9 TRUE FALSE FALSE 2082.499889 2092.692145 2266.392846 2301.636867 1747.11537 2039.09302 2452.122293 3625.52137 2346.481274 2465.705598 0.844585781 0.848719388 0.919166039 0.933459724 0.708566088 0.826981543 0.994491108 1.470378854 0.951646975 1 11.26778484 -4.276773676 3.338723545 0.898743034 1.537075589 0.83315441 0.078707542 0.104277262 1.922758171 0.012905467 0.166427953 5.29E-05 4.276773676 0.638332555 AVT(ph)PVSQGSNSSSADPK ddPTM_HeLa_Curcumin_4h_R1 2 AVTPVSQGSNSSSADPK 17 0 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 1 0 AVT(0.993)PVS(0.007)QGSNSSSADPK;AVT(0.678)PVS(0.163)QGS(0.009)NS(0.138)S(0.012)SADPK ; 195.96 2.74E-07 54679000 19024.6 15752.7 17319.2 16671.4 16356.7 20731.2 15479.8 5821.4 19021.1 17055 TRUE FALSE FALSE 17518.78284 17114.2932 17961.06479 16602.41816 16161.65704 16431.31543 15914.12153 7596.318062 16934.53292 17647.65998 0.992697211 0.969776912 1.017759001 0.940771648 0.915796035 0.931076157 0.901769501 0.43044336 0.959590843 1 14.10718928 -4.060860545 1.75064761 0.984766013 1.13E-12 0.954557534 0.034629052 0.241869472 0.475112025 0.005243098 0.465154565 8.69E-05 4.060860545 -0.984766013 down ATEPPS(ph)PDAGELSLASR ddPTM_HeLa_Curcumin_4h_R1 2 ATEPPSPDAGELSLASR 17 0 Q8IYB8 Q8IYB8 SUPV3L1 "ATP-dependent RNA helicase SUPV3L1, mitochondrial" 1 0 ATEPPS(1)PDAGELSLASR;ATEPPS(1)PDAGELSLASR ; 201.4 1.60E-10 52738000 3921.3 3647.6 3774 4602.2 4301.7 5605.5 4524.4 5907.6 4938.5 3596.6 TRUE FALSE FALSE 3610.924967 3962.882291 3913.86776 4583.157316 4250.405037 4442.856113 4651.342487 7708.800045 4396.758906 3721.581582 0.97026624 1.064838215 1.051667866 1.231507953 1.142096429 1.193808604 1.24982951 2.071377417 1.181422148 1 11.86170015 -1.087578803 0.786354583 1.01421396 200 0.887913619 0.100275981 72.01634199 0.292695205 0.014606832 25449.80309 0.081737471 1.087578803 198.985786 up TQTPPVSPAPQPTEERLPS(ph)SPVYEDAASFK ddPTM_HeLa_Curcumin_4h_R1 4 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 1 0 TQTPPVSPAPQPT(0.046)EERLPS(0.449)S(0.449)PVY(0.055)EDAASFK;TQTPPVSPAPQPT(0.141)EERLPS(0.409)S(0.409)PVY(0.04)EDAAS(0.001)FK;TQTPPVS(0.001)PAPQPT(0.01)EERLPS(0.471)S(0.471)PVY(0.047)EDAASFK;TQTPPVS(0.001)PAPQPT(0.01)EERLPS(0.473)S(0.473)PVY(0.043)EDAASFK ;;; 83.647 1.82E-06 1608620000 21882.7 17028.9 19242.2 19881.6 20085.2 28807.1 27474.4 26302 22273.9 18550.7 TRUE FALSE FALSE 20150.6612 18500.80224 19955.33286 19799.33521 19845.69711 22832.18274 28245.25772 34321.35872 19830.5089 19195.33544 1.049768641 0.963817605 1.039592818 1.031465966 1.033881235 1.18946516 1.471464659 1.788005155 1.03308999 1 14.22846815 -4.510034272 1.305979406 1.01914638 1.942909268 0.990856684 0.024029886 0.061073202 0.122022345 0.003968385 0.066145152 3.09E-05 4.510034272 0.923762887 TQTPQLHFLDT(ph)DDEVSPTSWGDSR ddPTM_HeLa_Curcumin_4h_R1 1 TQTPQLHFLDTDDEVSPTSWGDSR 24 0 Q86US8 Q86US8 SMG6 Telomerase-binding protein EST1A 1 0 TQTPQLHFLDT(0.998)DDEVS(0.001)PTSWGDSR 80.943 0.0002253 11068000 2280.4 2427.7 2294.6 2562.6 2328.3 3579 2468.6 1010 3358.7 2778.5 TRUE FALSE FALSE 2099.903934 2637.53957 2379.639895 2551.99664 2300.536543 2836.675056 2537.862272 1317.944351 2990.259013 2875.052668 0.730387988 0.917388262 0.82768567 0.887634744 0.800171965 0.98665151 0.882718532 0.458407029 1.040071038 1 11.48937267 -9.513020512 1.232842572 1.001157838 0.814972879 0.26605186 0.13676896 0.596477952 1.606514232 0.094584997 0.022209349 3.07E-10 9.513020512 -0.186184959 TQTTSAK(ac)QEK ddPTM_HeLa_Curcumin_4h_R1 2 TQTTSAKQEK 10 1 D6RIY6;Q06265-3;Q06265-4;Q06265;Q06265-2 D6RIY6 EXOSC9 Exosome complex component RRP45 0 1 ; TQTTSAK(1)QEK;TQTTSAK(1)QEK 192.5 3.19E-20 5267400 1730.38 2165.1 1865.67 1523.04 1498.14 2431.7 2500.2 2090.8 2033.95 1780.98 FALSE TRUE FALSE 1593.418597 2352.241597 1934.813371 1516.738064 1480.275659 1927.338009 2570.348883 2728.275295 1810.830774 1842.868922 0.864640224 1.27640201 1.049892018 0.823030898 0.803245223 1.045835646 1.394754045 1.480449999 0.982615069 1 10.84773774 -4.775353037 3.407055197 0.95233965 1.462182679 0.671718658 0.128672416 0.099551401 2.370989741 0.019179178 0.075802279 1.68E-05 4.775353037 0.509843029 TQVAGGQLSFK(ac)GK ddPTM_HeLa_Curcumin_4h_R1 2 TQVAGGQLSFKGK 13 1 B0QYT5;B0QYT4;P46060;B0QYT6 B0QYT5 RANGAP1 Ran GTPase-activating protein 1 0 1 ; TQVAGGQLSFK(1)GK;TQVAGGQLSFK(1)GK 184.21 6.47E-09 3952300 2384.58 2204.29 1298.46 1878.97 1719.89 2138.76 1501.5 1540.96 2108.05 1643.8 FALSE TRUE FALSE 2195.837977 2394.819005 1346.58207 1871.19532 1699.381435 1695.157067 1543.628049 2010.79161 1876.802189 1700.921928 1.290969292 1.407953514 0.791677765 1.10010653 0.999094319 0.996610744 0.907524339 1.182177487 1.103402901 1 10.73210121 -6.752580196 24.99874634 1.161532702 0.997041394 0.317871622 0.142140363 243.8004293 687951.0659 0.025652102 0.03597071 1.77E-07 6.752580196 -0.164491308 TRDDGDEEGLLT(ph)HSEEELEHS(ph)QDTDADDGALQ ddPTM_HeLa_Curcumin_4h_R1 2 TRDDGDEEGLLTHSEEELEHSQDTDADDGALQ 32 1 Q9UKM9-2;Q9UKM9 Q9UKM9-2 RALY RNA-binding protein Raly 2 0 TRDDGDEEGLLT(0.541)HS(0.453)EEELEHS(0.503)QDT(0.503)DADDGALQ;TRDDGDEEGLLT(0.645)HS(0.355)EEELEHS(0.537)QDT(0.463)DADDGALQ ; 84.408 3.09E-07 142510000 1776.33 1932.85 1920.2 1663.46 1747.16 2141.2 1287.31 1425.77 2121.92 1969.24 TRUE FALSE FALSE 1635.731606 2099.916941 1991.364301 1656.577043 1726.326258 1697.090984 1323.428454 1860.48071 1889.150685 2037.670943 0.802745709 1.03054762 0.97727472 0.81297574 0.847205612 0.832858215 0.649480947 0.913042764 0.927112737 1 10.99270538 -6.180919666 7.421684492 0.920474747 0.804733574 0.365651966 0.086051252 0.326077134 26.61013495 0.015195154 0.025265012 6.59E-07 6.180919666 -0.115741173 TRDDGDEEGLLTHS(ph)EEELEHSQDTDADDGALQ ddPTM_HeLa_Curcumin_4h_R1 1 TRDDGDEEGLLTHSEEELEHSQDTDADDGALQ 32 1 Q9UKM9-2;Q9UKM9 Q9UKM9-2 RALY RNA-binding protein Raly 1 0 TRDDGDEEGLLT(0.022)HS(0.678)EEELEHS(0.15)QDT(0.15)DADDGALQ 70.718 1.72E-05 223640000 924.08 890.93 910.08 851.12 929.02 1075.9 826.56 716.64 1054.5 1087.9 TRUE FALSE FALSE 850.9380929 967.9380193 943.8083654 847.598291 917.9420433 852.7462121 849.751049 935.140237 938.8239882 1125.704444 0.755916082 0.859850936 0.838415776 0.752949227 0.815437878 0.757522293 0.754861592 0.830715595 0.833987991 1 10.13661238 -9.390074464 0.772537983 1.021941139 0.791559538 0.217123585 0.06343955 0.28525621 0.256331618 0.043151469 0.007681501 4.07E-10 9.390074464 -0.230381601 TRDDGDEEGLLTHSEEELEHS(ph)QDTDADDGALQ ddPTM_HeLa_Curcumin_4h_R1 2 TRDDGDEEGLLTHSEEELEHSQDTDADDGALQ 32 1 Q9UKM9-2;Q9UKM9 Q9UKM9-2 RALY RNA-binding protein Raly 1 0 TRDDGDEEGLLTHS(0.199)EEELEHS(0.4)QDT(0.4)DADDGALQ;TRDDGDEEGLLTHS(0.152)EEELEHS(0.738)QDT(0.109)DADDGALQ ; 93.176 7.10E-09 130336500 1632.13 1470.33 1307.85 1582.7 1655.11 2043.14 1492.7 1156.06 1472.44 1666.03 TRUE FALSE FALSE 1502.945188 1597.418774 1356.320072 1576.151207 1635.373894 1619.369733 1534.581145 1508.537372 1310.917016 1723.924418 0.871816173 0.926617638 0.786763072 0.914280922 0.948634335 0.939350772 0.8901673 0.875060041 0.760426038 1 10.75148081 -9.321156886 0.964605952 1.002148849 0.894054998 0 0.086074727 0.434350412 0.700801795 0.033422231 0.008181594 4.77E-10 9.321156886 -0.108093852 TRDELDQFLDKMDDPDYWR ddPTM_HeLa_Curcumin_4h_R1 2 TRDELDQFLDKMDDPDYWR 19 2 Q14137;Q14137-2;A0A075B729 Q14137 BOP1 Ribosome biogenesis protein BOP1 0 0 ; ; 96.096 0.00052332 39820000 3674.3 3567.8 3343.1 3955.8 3196.6 5398.6 4049.1 3423.1 4591.7 3996.6 FALSE FALSE TRUE 3383.475278 3876.184734 3466.998227 3939.431948 3158.482633 4278.869505 4162.706848 4466.787432 4088.001998 4135.481553 0.818157507 0.937299486 0.838354175 0.952593283 0.763752079 1.034672613 1.006583344 1.080113011 0.988518978 1 12.01383962 -5.065836881 24.9799568 0.902398157 1.037668619 0.435027854 0.07339567 148.5642261 56368.27024 0.011481726 0.029272802 8.59E-06 5.065836881 0.135270462 TRDELEVIHLIEEHR ddPTM_HeLa_Curcumin_4h_R1 2 TRDELEVIHLIEEHR 15 1 P10155-3;P10155-5;P10155-4;P10155 P10155-3 TROVE2 60 kDa SS-A/Ro ribonucleoprotein 0 0 ; ; 132.51 0.00015914 26509300 5653.5 3757.8 4094.2 5018.5 4621.7 5064 4018 3293 5134 4279 FALSE FALSE TRUE 5206.019509 4082.607488 4245.934654 4997.734777 4566.589246 4013.669317 4130.734266 4297.020541 4570.813045 4427.694931 1.175785502 0.922061603 0.958949232 1.128744156 1.031369441 0.906491838 0.932931092 0.970487038 1.032323391 1 12.11234011 -5.396992843 4.790700108 1.064568293 0.93715677 0.219878923 0.074437791 0.225166889 7.813823249 0.013054582 0.029863497 4.01E-06 5.396992843 -0.127411523 TREEECHFYAGGQVYPGEASR ddPTM_HeLa_Curcumin_4h_R1 1 TREEECHFYAGGQVYPGEASR 21 1 Q13162;A6NG45 Q13162 PRDX4 Peroxiredoxin-4 0 0 79.461 0.0005656 10218000 1737 2095.5 2126.3 2031 1844.6 2048.5 1259.4 1231.2 2311.6 1771.4 FALSE FALSE TRUE 1599.514617 2276.625683 2205.102548 2022.59626 1822.60435 1623.618009 1294.735374 1606.587212 2058.023263 1832.956018 0.872642115 1.242051451 1.203030802 1.103461425 0.994352473 0.885792126 0.706364671 0.876500689 1.122789223 1 10.83995645 -5.067313595 3.571279859 0.997475288 0.790727053 0.376372906 0.126439961 0.243237636 6.02954418 0.020520591 0.060113947 8.56E-06 5.067313595 -0.206748235 TREEEEDSTIEASDQVS(ph)DDTVEMPLPK ddPTM_HeLa_Curcumin_4h_R1 2 TREEEEDSTIEASDQVSDDTVEMPLPK 27 1 P12270 P12270 TPR Nucleoprotein TPR 1 0 TREEEEDSTIEAS(0.002)DQVS(0.499)DDT(0.499)VEMPLPK;TREEEEDSTIEAS(0.114)DQVS(0.442)DDT(0.442)VEMPLPK ; 77.053 5.47E-05 31122000 5499.2 4070 4388 4826.6 4096.6 5866 4175.2 3851.4 5530.7 4074.7 TRUE FALSE FALSE 5063.932517 4421.792664 4550.62314 4806.628808 4047.750721 4649.325477 4292.344875 5025.67413 4923.996047 4216.295522 1.201038326 1.04873879 1.079294162 1.140012313 0.960025382 1.102703891 1.018037007 1.191964393 1.167848891 1 12.04176027 TREEIQEVR ddPTM_HeLa_Curcumin_4h_R1 4 TREEIQEVR 9 1 P08559-3;P08559;P08559-2;P08559-4;Q5JPU3;P29803 P08559-3 PDHA1;PDHA2 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial" 0 0 ;;; ;;; 112.83 0.0035349 14575600 9241.7 8272.3 7732.9 9547.1 8935.9 13947.6 10333.7 8304.8 9971.9 7496.1 FALSE FALSE TRUE 8510.209693 8987.320751 8019.488077 9507.59663 8829.345229 11054.71054 10623.63581 10836.89529 8878.007518 7756.588917 1.097158788 1.15866921 1.033893656 1.225744555 1.138302587 1.42520258 1.369627284 1.397121261 1.144576258 1 12.92120663 -4.88447579 0.373896564 1.022265496 1.624856555 0.726995584 0.074947816 1.107645659 0.147823246 0.020930978 0.278560083 1.30E-05 4.88447579 0.602591059 TREPLILEEEREMER ddPTM_HeLa_Curcumin_4h_R1 1 TREPLILEEEREMER 15 2 Q9UNX4 Q9UNX4 WDR3 WD repeat-containing protein 3 0 0 73.877 0.0091749 2755600 929.53 1003.3 648.15 888.72 844.24 745.61 590.33 512.77 750.88 730.67 FALSE FALSE TRUE 855.9567197 1090.020781 672.1710092 885.0427121 834.1729894 590.9620812 606.893071 669.1112125 668.5103426 756.0607281 1.132126941 1.44171062 0.889043676 1.170597386 1.103314798 0.781633087 0.802704133 0.884996651 0.884201914 1 9.562358309 -5.264916193 24.55955475 1.090262236 0.821070567 0.392789484 0.151317202 162.1575133 1145456.172 0.019681142 0.045735857 5.43E-06 5.264916193 -0.26919167 TRNS(ph)GIWESPELDR ddPTM_HeLa_Curcumin_4h_R1 3 TRNSGIWESPELDR 14 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 0 TRNS(1)GIWESPELDR;T(0.002)RNS(0.998)GIWESPELDR;TRNS(1)GIWESPELDR ;; 108.97 0.0013674 42853700 4431.9 3553.7 4381.4 4326.82 4331.1 5177.4 3995.1 3669.3 4337.3 3922.79 TRUE FALSE FALSE 4081.110438 3860.865993 4543.778538 4308.916765 4279.454461 4103.548879 4107.191754 4788.052679 3861.509041 4059.106661 1.005420843 0.951161503 1.119403583 1.061543124 1.054284802 1.010948768 1.011846226 1.179582869 0.951319924 1 11.98694653 -6.764452623 24.99997905 0.998776494 1.065975045 0.429527623 0.051420271 70.11422016 581718.33 0.00751098 0.010116059 1.72E-07 6.764452623 0.067198551 TRPGS(ph)FQSLSDALSDTPAK ddPTM_HeLa_Curcumin_4h_R1 1 TRPGSFQSLSDALSDTPAK 19 1 G3V4K3;Q9H9C1-2;Q9H9C1 G3V4K3 VIPAS39 Spermatogenesis-defective protein 39 homolog 1 0 T(0.004)RPGS(0.996)FQSLSDALSDTPAK 135.43 0.0018174 13582000 1073.3 621.27 464.26 698.75 641.15 1329.2 1089.6 765.64 1063.6 620.26 TRUE FALSE FALSE 988.3471725 674.9698105 481.465884 695.8587576 633.504705 1053.508937 1120.171243 999.0801114 946.925741 641.8139888 1.539927751 1.05165955 0.75016421 1.084206281 0.987053439 1.641455243 1.745320705 1.55665057 1.475389688 1 9.326011424 -5.243849256 22.70390566 1.177384244 1.657560336 0.518122994 0.226513993 199.7257745 257787.3008 0.038588019 0.098032999 5.70E-06 5.243849256 0.480176093 GS(ph)PTGGAQLLKR ddPTM_HeLa_Curcumin_4h_R1 1 GSPTGGAQLLKR 12 1 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 0 GS(0.841)PT(0.159)GGAQLLKR 100.02 0.014629 34616000 2413.8 2106 1998.1 2234.4 1689.5 2287.3 1595.8 688.94 2350.8 2029.6 TRUE FALSE FALSE 2222.745183 2288.033256 2072.151344 2225.154645 1669.353816 1812.888197 1640.573853 898.9946345 2092.923121 2100.128449 1.05838535 1.089473007 0.986678384 1.059532642 0.794881769 0.863227293 0.781177863 0.4280665 0.996569102 1 11.03626185 -4.060554449 0.684070311 1.032041395 2.70E-12 0.872511724 0.067951332 0.877934472 0.237162131 0.011222102 0.746470907 8.70E-05 4.060554449 -1.032041395 down AAHTEDINACTLTT(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 AAHTEDINACTLTTSPR 17 0 H7C155;P04049;P04049-2 H7C155 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 0 AAHTEDINACT(0.193)LT(0.193)T(0.307)S(0.307)PR 79.565 0.0091672 73493000 2146.2 1724.5 1963.5 1785.1 2259.9 3231.8 2500.6 3174.6 2404.7 1966 TRUE FALSE FALSE 1976.326005 1873.558096 2036.269037 1777.713729 2232.952168 2561.48825 2570.760106 4142.520926 2140.910426 2034.318354 0.971492983 0.92097586 1.000958888 0.87386211 1.09764146 1.259138347 1.263696069 2.036318907 1.052396948 1 10.99032975 -1.05454604 0.773021813 0.976661747 199.9999999 0.943829192 0.07598528 51.42215692 0.208444097 0.01108436 17857.96819 0.08819703 1.05454604 199.0233382 up TRS(ph)PDVISSASTALSQDIPEIASEALSR ddPTM_HeLa_Curcumin_4h_R1 1 TRSPDVISSASTALSQDIPEIASEALSR 28 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 0 T(0.05)RS(0.542)PDVIS(0.174)S(0.174)AS(0.056)T(0.004)ALSQDIPEIASEALSR 129.04 1.63E-10 32160000 1370.4 1104.3 1249.3 1361.8 1310.2 1602.2 892.33 631.57 1376.8 1393.2 TRUE FALSE FALSE 1261.931394 1199.750771 1295.600157 1356.165232 1294.576721 1269.885659 917.3663782 824.1327856 1225.768485 1441.613596 0.875360358 0.832227703 0.898715273 0.940727277 0.898005349 0.880877971 0.636346924 0.571673844 0.850275336 1 10.49346881 -4.745147466 2.728098373 0.925408755 0.575159735 0.847394618 0.049273322 0.079739928 1.159471722 0.008505601 0.039601237 1.80E-05 4.745147466 -0.35024902 TRS(ph)WDSSSPVDRPEPEAASPTTR ddPTM_HeLa_Curcumin_4h_R1 1 TRSWDSSSPVDRPEPEAASPTTR 23 2 C9J0I9;Q86WB0;Q86WB0-2 C9J0I9 ZC3HC1 Nuclear-interacting partner of ALK 1 0 T(0.223)RS(0.73)WDS(0.013)S(0.017)S(0.017)PVDRPEPEAASPTTR 62.303 0.0041605 14106000 559.59 810.59 758.95 729.87 670.57 1172.2 1495.4 963.09 842.6 692.98 TRUE FALSE FALSE 515.297861 880.6537877 787.0773546 726.8499913 662.5738907 929.0725066 1537.356899 1256.731707 750.1688881 717.0610034 0.718624857 1.228143468 1.097643507 1.013651541 0.924013281 1.295667317 2.14396947 1.752614773 1.046171643 1 9.48595205 -4.948004724 3.484598499 0.926852528 1.94544053 0.825611294 0.167992045 0.065983839 1.640886158 0.026692833 0.088663837 1.13E-05 4.948004724 1.018588002 TRSEGGGTGESSQGGTSK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 TRSEGGGTGESSQGGTSKR 19 2 F5H0R1;Q9H6E5 F5H0R1 TUT1 Speckle targeted PIP5K1A-regulated poly(A) polymerase 0 1 ; TRSEGGGTGESSQGGTSK(1)R;TRSEGGGTGESSQGGTSK(1)R 69.975 0.0040869 381130 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 TRSPDVIS(ph)SASTALSQDIPEIASEALSR ddPTM_HeLa_Curcumin_4h_R1 1 TRSPDVISSASTALSQDIPEIASEALSR 28 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 1 0 T(0.049)RS(0.049)PDVIS(0.273)S(0.273)AS(0.273)T(0.079)ALS(0.003)QDIPEIASEALSR 45.125 0.014089 9302400 621.31 390.3 689.67 532.56 396.06 673.8 462.15 308.8 643.76 636.87 TRUE FALSE FALSE 572.1326579 424.0357929 715.2297769 530.3564078 391.3372432 534.0462847 475.1166852 402.9516985 573.1411386 659.0011851 0.868181531 0.643452246 1.085323962 0.804788246 0.593833899 0.810387442 0.720964842 0.61145823 0.869711848 1 9.364137249 -2.745104251 0.099346742 1.159438043 1.19E-11 0.313915793 0.128279541 56.04627675 0.590344893 1.192211465 8.993263794 0.001798439 2.745104251 -1.159438043 TRSPDVISSASTALSQDIPEIASEALSR ddPTM_HeLa_Curcumin_4h_R1 1 TRSPDVISSASTALSQDIPEIASEALSR 28 1 Q6P2E9;Q6P2E9-2 Q6P2E9 EDC4 Enhancer of mRNA-decapping protein 4 0 0 103.59 3.29E-06 0 346.89 226.98 301.83 333.8 391.36 359.8 232.77 297.88 378.15 249.83 FALSE FALSE TRUE 319.4332905 246.5991398 313.0160853 332.418824 386.6932876 285.1734242 239.3008997 388.7022407 336.6678911 258.5115739 1.2356634 0.953919146 1.210839734 1.285895324 1.495845164 1.103136002 0.925687373 1.503616395 1.302331985 1 8.014085063 -13.20088705 0.227926245 9.04E-12 1.241664499 0 0.204047531 57.13226621 0.83643816 25.53978363 0.134769248 6.30E-14 13.20088705 1.241664499 TRT(ph)PASINATPANINLADLTR ddPTM_HeLa_Curcumin_4h_R1 2 TRTPASINATPANINLADLTR 21 1 Q7KZ85;Q7KZ85-2 Q7KZ85 SUPT6H Transcription elongation factor SPT6 1 0 T(0.046)RT(0.953)PAS(0.001)INATPANINLADLTR;T(0.222)RT(0.741)PAS(0.037)INATPANINLADLTR ; 169.77 1.46E-07 34630000 3600.39 2686.2 2860.25 2953.53 2812.93 4272.3 2569.77 1070.42 3509.35 2230.78 TRUE FALSE FALSE 3315.415332 2918.383159 2966.253381 2941.309075 2779.387647 3386.176821 2641.87083 1396.78613 3124.383085 2308.299439 1.4363021 1.264300077 1.285038384 1.274232028 1.204084531 1.466957347 1.144509584 0.60511479 1.353543233 1 11.17261467 -4.281795502 4.017050161 1.240405929 0.560267555 0.704799145 0.12908088 0.124130361 4.133873323 0.023937413 0.235738733 5.23E-05 4.281795502 -0.680138374 TRT(ph)YSATAR ddPTM_HeLa_Curcumin_4h_R1 1 TRTYSATAR 9 1 H7C4E7;Q9Y534 H7C4E7 CSDC2 Cold shock domain-containing protein C2 1 0 T(0.227)RT(0.748)YS(0.016)AT(0.01)AR 94.538 0.013372 2387000 847.79 506.27 609.38 719.26 422.8 695.39 380.26 394.63 1298.5 797.37 TRUE FALSE FALSE 780.6865269 550.0297229 631.9641589 716.2838927 417.7583861 551.1582753 390.9290722 514.9508703 1156.057799 825.0785481 0.946196612 0.666639224 0.765944237 0.868140245 0.506325594 0.668007036 0.47380831 0.62412345 1.401148777 1 9.688387661 -6.539144759 0.485413781 1.005688695 0.524548047 0.624682054 0.160540791 0.349737294 0.170847079 0.030392577 0.068308809 2.89E-07 6.539144759 -0.481140648 TRTDSYS(ph)AGQSVEILDGVELGEPAHKK ddPTM_HeLa_Curcumin_4h_R1 1 TRTDSYSAGQSVEILDGVELGEPAHKK 27 2 B1AKQ2;B1AKP8;P42345 B1AKQ2 MTOR Serine/threonine-protein kinase mTOR 1 0 T(0.132)RT(0.132)DS(0.192)Y(0.233)S(0.283)AGQS(0.027)VEILDGVELGEPAHKK 84.156 1.06E-05 4298400 1997 1800.7 1762.6 2275.3 1860.6 2442.6 1353.5 916.12 2462.3 2251 TRUE FALSE FALSE 1838.935343 1956.344484 1827.923507 2265.885411 1838.41356 1935.977226 1391.475567 1195.440771 2192.19185 2329.222082 0.789506229 0.839913248 0.784778541 0.972807801 0.789282213 0.831169016 0.597399268 0.513236063 0.9411691 1 11.18563249 -3.860186476 0.649055071 0.894414055 4.94E-20 0.733219624 0.075865481 2.231186993 0.453502801 0.016322357 1.663297736 0.000137979 3.860186476 -0.894414055 TRTLLSDPTY(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 TRTLLSDPTYR 11 1 P31948;P31948-2;P31948-3;F5H783 P31948 STIP1 Stress-induced-phosphoprotein 1 1 0 TRTLLSDPTY(1)R 85.958 0.0041624 0 1411.9 1289.3 1979.7 1374.1 2525 3401.2 1874.6 2162.6 2348.3 1284.8 TRUE FALSE FALSE 1300.146625 1400.741347 2053.069424 1368.414338 2494.891024 2695.752781 1927.196231 2821.966785 2090.697365 1329.446704 0.977960697 1.053627304 1.544303669 1.029311167 1.876638617 2.027725347 1.449622783 2.12266259 1.572607129 1 10.37661023 -6.027660463 0.87731321 0.986953661 1.899470572 0.456145311 0.308434439 0.232788229 0.347471351 0.04144305 0.112394107 9.38E-07 6.027660463 0.912516911 TRVS(ph)LGGEPPSEAQPQPEVPLGGLSEAADSLR ddPTM_HeLa_Curcumin_4h_R1 1 TRVSLGGEPPSEAQPQPEVPLGGLSEAADSLR 32 1 Q9BVQ7-3;Q9BVQ7-2;Q9BVQ7 Q9BVQ7-3 SPATA5L1 Spermatogenesis-associated protein 5-like protein 1 1 0 T(0.138)RVS(0.857)LGGEPPS(0.004)EAQPQPEVPLGGLSEAADSLR 86.144 1.87E-07 0 239.93 152.39 222.04 190.56 157.86 258.38 160.66 196.41 173.32 293.5 TRUE FALSE FALSE 220.9392873 165.5619126 230.2689977 189.7715132 155.9776226 204.7890755 165.1676872 256.2945048 154.3072296 303.6991032 0.727494039 0.545151141 0.758214283 0.624866887 0.513592635 0.674315707 0.543853062 0.843909324 0.508092477 1 8.246498838 -8.597700566 0.594421997 1.007588568 0.632266965 0 0.179590087 0.355275261 0.249535141 0.064588538 0.02399156 2.53E-09 8.597700566 -0.375321603 ESTESSNT(ph)TIEDEDVK ddPTM_HeLa_Curcumin_4h_R1 2 ESTESSNTTIEDEDVK 16 0 H0Y9J2;D6R938;Q13557-8;Q13557-12;Q13557;E9PBG7;E9PF82;Q13557-10;Q13557-6;Q13557-11 H0Y9J2 CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta 1 0 ESTESSNT(0.711)T(0.289)IEDEDVK;ESTESS(0.003)NT(0.498)T(0.498)IEDEDVK ; 186.98 9.55E-06 80157000 9272.6 8057.7 8949.4 8583.3 10618 12138.4 11247 14362.4 8145.3 7443.2 TRUE FALSE FALSE 8538.663926 8754.171684 9281.072637 8547.784579 10491.38728 9620.759012 11562.56055 18741.42964 7251.780969 7701.850646 1.108650936 1.136632231 1.205044484 1.109835152 1.362190435 1.249148997 1.50127042 2.433367057 0.941563437 1 12.91098943 -1.026285988 0.730957571 1.076314284 200 0.94218074 0.097916712 46.39980006 0.21229719 0.015621999 15162.52939 0.094126956 1.026285988 198.9236857 up TS(ph)GETTQTHTEPTGDSK ddPTM_HeLa_Curcumin_4h_R1 2 TSGETTQTHTEPTGDSK 17 0 P46013;P46013-2 P46013 MKI67 Antigen KI-67 1 0 T(0.421)S(0.578)GET(0.001)TQTHTEPTGDSK;T(0.19)S(0.789)GET(0.006)T(0.006)QT(0.009)HTEPTGDSK ; 134.58 0.00016496 28093000 6526 4861 5352.4 7340 7926.8 11922.2 13496.7 3119.46 7565.9 5836.4 TRUE FALSE FALSE 6009.460214 5281.16318 5550.764652 7309.629025 7832.278087 9449.401329 13875.38108 4070.568994 6735.939699 6039.214466 0.995073159 0.874478495 0.919120307 1.210360895 1.296903452 1.564673913 2.297547331 0.674022924 1.115366864 1 12.56014519 -5.704168795 1.874449832 0.983795855 1.57684775 0.265199269 0.373399899 0.273201312 1.9460164 0.050843514 0.11891462 1.98E-06 5.704168795 0.593051894 TS(ph)IETNIR ddPTM_HeLa_Curcumin_4h_R1 2 TSIETNIR 8 0 P14859-6;P14859-2;P14859;P14859-3;P14859-5;P14859-4;A0A0C4DG88;A0A0A0MT46;Q9UKI9;Q9UKI9-2;H0YLC5;Q9UKI9-3 P14859-6 POU2F1;POU2F3 "POU domain, class 2, transcription factor 1;POU domain protein;POU domain, class 2, transcription factor 3" 1 0 T(0.203)S(0.797)IETNIR;T(0.025)S(0.972)IET(0.003)NIR ; 134.84 0.0042096 29093000 4702.2 3643.3 3914.4 4217.5 5069 6300.8 5229.9 4830.7 4652.5 3977.1 TRUE FALSE FALSE 4330.015908 3958.210618 4059.471107 4200.049102 5008.555486 4993.943055 5376.636918 6303.558192 4142.13239 4115.303929 1.052174027 0.961827045 0.98643288 1.020592689 1.217056036 1.213505282 1.306498137 1.53173576 1.006519193 1 12.00678327 -4.234969254 0.646497633 1.013608769 1.859113116 0.927451717 0.047129089 0.633719515 0.176866395 0.008954283 0.397825281 5.82E-05 4.234969254 0.845504348 TS(ph)PDTLR ddPTM_HeLa_Curcumin_4h_R1 1 TSPDTLR 7 0 J3KP15;Q01130;J3QL05;Q01130-2 J3KP15 SRSF2 Serine/arginine-rich splicing factor 2 1 0 T(0.223)S(0.775)PDT(0.002)LR 114.89 0.0088013 420460000 9520.8 8509 8780.4 8260 9685.4 9039.4 8281.7 8505.4 7569 6617.1 TRUE FALSE FALSE 8767.218634 9244.480045 9105.809348 8225.822309 9569.907931 7164.526545 8514.062213 11098.65731 6738.699637 6847.043732 1.280438533 1.350141814 1.329889176 1.201368449 1.397670046 1.046367867 1.243465435 1.620941495 0.984176515 1 12.74126551 -9.047298888 0.630744123 0.97514715 1.30383524 0.448849201 0.139595926 0.733608356 0.483178121 0.131281907 0.03096595 8.97E-10 9.047298888 0.32868809 TS(ph)PDTLRR ddPTM_HeLa_Curcumin_4h_R1 1 TSPDTLRR 8 1 J3KP15;Q01130;J3QL05;Q01130-2 J3KP15 SRSF2 Serine/arginine-rich splicing factor 2 1 0 T(0.399)S(0.6)PDTLRR 94.309 0.0086162 65174000 3673.2 3212.7 3575 3334.7 3448.5 4296.4 3786.8 3584.9 3468.2 2976.9 TRUE FALSE FALSE 3382.462344 3490.391472 3707.492645 3320.901895 3407.37889 3405.27821 3893.047416 4677.919507 3087.747137 3080.347053 1.098078329 1.133116305 1.203595757 1.078093422 1.106167205 1.105485243 1.263834025 1.518633916 1.002402354 1 11.58887719 -1 0.669229273 1.063536658 47.73328497 0.839730837 0.057744572 68.78762831 0.383380421 0.011212907 4784.629261 0.1 1 46.66974831 TS(ph)PINEDIR ddPTM_HeLa_Curcumin_4h_R1 2 TSPINEDIR 9 0 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 0 T(0.228)S(0.772)PINEDIR;T(0.224)S(0.776)PINEDIR ; 128.51 0.0041524 78477000 6333.3 6057.5 5778.6 5587.1 6772.9 6076.1 5443.4 3591.1 5416.9 4976.7 TRUE FALSE FALSE 5832.012622 6581.083308 5992.759999 5563.982061 6692.137591 4815.848368 5596.127154 4686.009859 4822.679622 5149.639955 1.132508811 1.277969599 1.163724076 1.080460403 1.299535045 0.935181568 1.086702605 0.909968444 0.936508118 1 12.33025585 -3.846193662 1.192952453 1.099152687 0.638052645 0.197989445 0.118138604 4.859407759 2.924536462 0.017148629 3.526991393 0.000142497 3.846193662 -0.461100042 TS(ph)PLVSQNNEQGSTLR ddPTM_HeLa_Curcumin_4h_R1 1 TSPLVSQNNEQGSTLR 16 0 A0A1W2PNZ9;Q15652-3;Q15652;H7BXU7 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 0 T(0.193)S(0.807)PLVSQNNEQGSTLR 74.966 0.018382 8055900 2132.4 2023.4 2323.5 2100.4 2265.5 2443.3 2280.2 1562.6 2261.5 1796.3 TRUE FALSE FALSE 1963.61829 2198.29368 2409.610954 2091.709101 2238.485392 1936.532038 2344.176275 2039.029547 2013.419108 1858.721291 1.056435034 1.182691397 1.296380993 1.125348438 1.20431471 1.041862515 1.261176856 1.097006612 1.083228087 1 10.86009474 -7.380549119 3.246837576 1.023480349 1.175259725 0.377158989 0.073328875 0.150339527 2.884637774 0.01202438 0.01364477 4.16E-08 7.380549119 0.151779376 TS(ph)PPCSPANLSR ddPTM_HeLa_Curcumin_4h_R1 1 TSPPCSPANLSR 12 0 C9JEJ2;P49585 C9JEJ2 PCYT1A Choline-phosphate cytidylyltransferase A 1 0 T(0.473)S(0.527)PPCSPANLSR 109.16 0.0058298 110640000 1668.9 1438.6 1458.1 1749.5 1775.8 2184 1372.8 1676.1 1858.9 1561.3 TRUE FALSE FALSE 1536.804804 1562.946174 1512.138469 1742.261033 1754.624745 1731.013781 1411.317073 2187.135174 1654.983321 1615.555059 0.951254985 0.967436031 0.93598696 1.078428756 1.086081675 1.071466907 0.8735803 1.353797979 1.024405397 1 10.6578142 -6.247742787 23.23884191 0.972733973 1.07895534 0.212186682 0.110940369 380.8334534 646153.2843 0.014934831 0.024659304 5.65E-07 6.247742787 0.106221368 TS(ph)PPLLDR ddPTM_HeLa_Curcumin_4h_R1 1 TSPPLLDR 8 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 T(0.223)S(0.777)PPLLDR 104.42 0.012925 2619000 2310 2113.2 2682.1 2651.9 2426.9 2691.7 2275.6 2228.8 2494.8 2343.5 TRUE FALSE FALSE 2127.161062 2295.855592 2781.500985 2640.92714 2397.960803 2133.411078 2339.447212 2908.35086 2221.126682 2424.936451 0.877202808 0.946769385 1.147040775 1.08907066 0.98887573 0.879780201 0.964745782 1.199351372 0.915952532 1 11.24373122 -6.954395191 24.99622046 0.940431962 1.034286588 0.256230627 0.090485909 170.3086291 93346.55484 0.015882504 0.020873697 1.11E-07 6.954395191 0.093854626 TS(ph)PYILR ddPTM_HeLa_Curcumin_4h_R1 2 TSPYILR 7 0 P49454 P49454 CENPF Centromere protein F 1 0 T(0.076)S(0.924)PYILR;T(0.228)S(0.772)PYILR ; 127.46 0.008181 55107000 5844.7 5441.9 4698.5 5474.3 5457.2 7423.3 6677.6 1754.8 5935.3 4971.3 TRUE FALSE FALSE 5382.085828 5912.273587 4872.630543 5451.648797 5392.126454 5883.623902 6864.955484 2289.830442 5284.212439 5144.052305 1.046273542 1.149341655 0.947235808 1.059796533 1.048225433 1.143772177 1.334542317 0.445141361 1.027247027 1 12.3286896 -4.244095838 24.98024247 1.05383395 0.445140862 0.763750358 0.105404042 1387.134255 1997886.622 0.014485725 0.590103194 5.70E-05 4.244095838 -0.608693088 TS(ph)SAVWNSPPLQGAR ddPTM_HeLa_Curcumin_4h_R1 1 TSSAVWNSPPLQGAR 15 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 T(0.355)S(0.557)S(0.04)AVWNS(0.048)PPLQGAR 145.52 0.00048705 15362000 3778.4 2863.6 3409.1 3128.7 3142.4 5744.5 4200.3 1959.8 3560.9 2724.4 TRUE FALSE FALSE 3479.335653 3111.116824 3535.444245 3115.754268 3104.928932 4553.025946 4318.149113 2557.333998 3170.278179 2819.072697 1.234212816 1.103595813 1.254116025 1.105240837 1.101400803 1.615079296 1.531762241 0.907154328 1.124581917 1 11.46100497 -13.52287868 0.136332778 0.101470614 1.356982199 0.097711311 0.200569453 93.65208379 0.894644447 22.70090411 0.623462168 3.00E-14 13.52287868 1.255511585 SNSLPHS(ph)AVSNAGSK ddPTM_HeLa_Curcumin_4h_R1 1 SNSLPHSAVSNAGSK 15 0 A0A088AWN2;Q8TBZ3-4;Q8TBZ3-5;Q8TBZ3-6;Q8TBZ3;Q8TBZ3-2;Q8TBZ3-7 A0A088AWN2 WDR20 WD repeat-containing protein 20 1 0 SNS(0.006)LPHS(0.992)AVS(0.002)NAGSK 189.44 2.93E-06 8896700 2040 1423.4 1187.8 1605.3 2092.1 3150.9 2307 3236.9 1850.1 1542.3 TRUE FALSE FALSE 1878.531847 1546.432353 1231.820913 1598.657694 2067.153074 2497.367822 2371.728211 4223.815909 1647.148659 1595.89481 1.177102548 0.969006443 0.771868487 1.001731244 1.295294064 1.564869944 1.486143194 2.646675634 1.032116057 1 10.64014985 -1.022092408 0.706279347 1.050949687 199.9999998 0.905792477 0.155671572 60.37025696 0.302176442 0.027679882 18997.26407 0.095040255 1.022092408 198.9490502 up TS(ph)STCS(ph)NESLSVGGTSVTPR ddPTM_HeLa_Curcumin_4h_R1 1 TSSTCSNESLSVGGTSVTPR 20 0 A0A3B3IRT3;O60343-2;O60343-3;O60343;Q5JU47 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 2 0 T(0.415)S(0.504)S(0.075)T(0.055)CS(0.951)NESLSVGGTSVTPR 84.312 0.0044347 9048600 644.72 704.55 617.94 473.78 534.93 763.33 265.55 532.94 739.11 510.23 TRUE FALSE FALSE 593.6897317 765.4481626 640.8414 471.8196239 528.5513091 605.0067535 273.0006183 695.4309526 658.0314822 527.9604545 1.124496592 1.449821016 1.213805683 0.893664705 1.001119127 1.145931951 0.517085354 1.317202731 1.246365095 1 9.044286062 -6.251453721 24.83644353 1.106400905 0.960508225 0.136345327 0.22914315 1260.331066 3134709.101 0.033254728 0.054702615 5.60E-07 6.251453721 -0.145892679 TS(ph)STDEVLSLEEK ddPTM_HeLa_Curcumin_4h_R1 1 TSSTDEVLSLEEK 13 0 K7ENH8;A0A0A0MRB7;P15923-2;K7EMM4 K7ENH8 TCF3 Transcription factor E2-alpha 1 0 T(0.124)S(0.492)S(0.381)T(0.003)DEVLSLEEK 90.861 0.011729 70887000 1168.8 976.33 999.36 964.77 1275.6 1173.8 1295.4 1258.2 1274.4 1136.9 TRUE FALSE FALSE 1076.288247 1060.719615 1036.397161 960.7780374 1260.389303 930.3406485 1331.745438 1641.819388 1134.601508 1176.40719 0.914894312 0.901660261 0.880985061 0.816705343 1.071388643 0.790832168 1.132044626 1.395621687 0.964463255 1 10.20017179 -4.442881729 3.337947611 0.93792037 1.389870421 0.765583757 0.08202443 0.093705729 1.80909084 0.011154235 0.082385348 3.61E-05 4.442881729 0.451950051 TS(ph)SVSSISQVSPER ddPTM_HeLa_Curcumin_4h_R1 1 TSSVSSISQVSPER 14 0 P42356 P42356 PI4KA Phosphatidylinositol 4-kinase alpha 1 0 T(0.049)S(0.697)S(0.251)VS(0.002)S(0.001)ISQVSPER 96.707 0.0067468 16220000 1017.3 949.56 1200.2 1017.9 961.61 1125.8 946.42 988.21 1129.4 1027 TRUE FALSE FALSE 936.7796315 1031.635735 1244.680468 1013.6882 950.1434288 892.2963896 972.973998 1289.51068 1005.507646 1062.688174 0.881518826 0.970779351 1.171256535 0.953890544 0.894094291 0.839659659 0.91557808 1.213442204 0.946192562 1 10.05350261 -8.761377255 0.002759496 5.10E-08 1.914384674 0 0.116275959 377611.6401 346.7000058 121322.5004 119198.2034 1.73E-09 8.761377255 1.914384623 SSFASSSASDASKPSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 SSFASSSASDASKPSSPR 18 1 Q96IF1 Q96IF1 AJUBA LIM domain-containing protein ajuba 1 0 SSFASSSASDASKPS(0.009)S(0.991)PR;SSFASSSASDASKPS(0.001)S(0.999)PR;SSFASSS(0.002)ASDAS(0.006)KPS(0.034)S(0.958)PR ;; 332.61 1.11E-131 112463000 18037.4 14131.7 14377.2 14181.8 14864.9 17565.6 12131.5 5164.3 17619.2 13617.2 TRUE FALSE FALSE 16609.72076 15353.18118 14910.03168 14123.11947 14687.64578 13922.29655 12471.87724 6738.871296 15686.41784 14090.39669 1.178797242 1.089620223 1.05816976 1.002322346 1.042386961 0.988069879 0.885133153 0.478259871 1.113270136 1 13.78242461 -4.057954284 1.178579694 1.077222568 1.83E-12 0.924728013 0.050654208 0.59608771 0.497747855 0.010655703 0.879082874 8.75E-05 4.057954284 -1.077222568 down TS(ph)VAGTVR ddPTM_HeLa_Curcumin_4h_R1 1 TSVAGTVR 8 0 Q96EB6;B0QZ35;E9PC49 Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1;SirtT1 75 kDa fragment 1 0 T(0.223)S(0.777)VAGTVR 99.013 0.01563 10315000 3296.6 2934.5 2801.5 3369.4 2887.6 4307.9 3842.6 3316.5 3640 2959.8 TRUE FALSE FALSE 3035.670631 3188.145104 2905.326054 3355.458316 2853.167256 3414.39298 3950.413014 4327.685583 3240.701107 3062.65283 0.991189926 1.040975024 0.948630555 1.095605184 0.931599961 1.114848195 1.289866411 1.413051307 1.058135312 1 11.58056612 -4.739779045 1.968049526 0.999138158 1.410458998 0.887091691 0.048842986 0.065365741 0.456662001 0.005603549 0.034447053 1.82E-05 4.739779045 0.41132084 TSADAQEPAS(ph)PVVSPQQS(ph)PPT(ph)SPHTWR ddPTM_HeLa_Curcumin_4h_R1 1 TSADAQEPASPVVSPQQSPPTSPHTWR 27 0 E9PMG1;H0YDT0;Q96D71-4;Q96D71-3;Q96D71;F2Z3L2;Q96D71-2 E9PMG1 REPS1 RalBP1-associated Eps domain-containing protein 1 3 0 T(0.002)S(0.002)ADAQEPAS(0.994)PVVS(0.005)PQQS(0.995)PPT(0.491)S(0.424)PHT(0.087)WR 73.817 0.00013322 8633400 975.01 947.03 1038.1 1488.4 1433.9 1417.3 1167.8 1127.1 1503.2 1225.8 TRUE FALSE FALSE 897.8369297 1028.887053 1076.572899 1482.241395 1416.801679 1123.336004 1200.565325 1470.747601 1338.302721 1268.396459 0.707851968 0.811171496 0.848766876 1.168594713 1.117002235 0.885634768 0.946522136 1.15953304 1.055113889 1 10.30879004 -6.289327715 23.370205 0.85300729 1.043389984 0.303861823 0.124155755 297.7310515 249495.6205 0.021247955 0.03246338 5.14E-07 6.289327715 0.190382694 TSADAQEPASPVVS(ph)PQQSPPT(ph)SPHTWR ddPTM_HeLa_Curcumin_4h_R1 1 TSADAQEPASPVVSPQQSPPTSPHTWR 27 0 E9PMG1;H0YDT0;Q96D71-4;Q96D71-3;Q96D71;F2Z3L2;Q96D71-2 E9PMG1 REPS1 RalBP1-associated Eps domain-containing protein 1 2 0 TSADAQEPASPVVS(0.954)PQQS(0.045)PPT(0.494)S(0.494)PHT(0.013)WR 85.571 3.21E-05 17764000 1705.6 1484.6 1538.6 1509.1 1705.6 2064 1183.6 1018.8 2067.5 1555.3 TRUE FALSE FALSE 1570.59996 1612.922209 1595.621869 1502.855744 1685.261834 1635.903134 1216.808631 1329.42743 1840.700423 1609.346559 0.975924018 1.002221802 0.991471887 0.93382978 1.04717149 1.016501464 0.756088627 0.826066594 1.143756397 1 10.65225932 -4.763145357 24.99999138 0.991337802 0.791077569 0.69435831 0.057592354 9.494360711 139145.1352 0.004173043 0.01355596 1.73E-05 4.763145357 -0.200260233 TSADAQEPASPVVSPQQS(ph)PPTS(ph)PHTWR ddPTM_HeLa_Curcumin_4h_R1 1 TSADAQEPASPVVSPQQSPPTSPHTWR 27 0 E9PMG1;H0YDT0;Q96D71-4;Q96D71-3;Q96D71;F2Z3L2;Q96D71-2 E9PMG1 REPS1 RalBP1-associated Eps domain-containing protein 1 2 0 TSADAQEPAS(0.005)PVVS(0.089)PQQS(0.673)PPT(0.53)S(0.681)PHT(0.022)WR 69.803 0.00094515 14549000 2799.6 2621.5 2695.2 2528.3 2903.8 3295.4 2204.3 2133.9 3178.8 2465.4 TRUE FALSE FALSE 2578.008706 2848.090779 2795.086483 2517.838565 2869.174082 2611.896893 2266.146725 2784.516287 2830.093593 2551.072466 1.01055879 1.116428802 1.095651542 0.986972576 1.124693288 1.023842689 0.888311389 1.09150811 1.10937405 1 11.31688817 -3.926080426 20.90827375 1.019760761 3.611194188 0 0.072795141 1150.786128 331095.8461 0.008974766 2398.856462 0.000118555 3.926080426 2.591433426 TSAGTTDPEEATR ddPTM_HeLa_Curcumin_4h_R1 1 TSAGTTDPEEATR 13 0 Q14244-3;Q14244;Q14244-5;Q14244-6;Q14244-7;A0A087WZ40;Q14244-2;Q14244-4 Q14244-3 MAP7 Ensconsin 0 0 137.89 0.00074321 506530 882.79 637.89 771.52 513.23 705.32 965.81 682.74 421.13 568.74 550.92 FALSE FALSE TRUE 812.91624 693.0263692 800.1132099 511.1063902 696.9095197 765.4901191 701.8958469 549.5305984 506.3506449 570.064429 1.426007656 1.215698321 1.403548738 0.896576535 1.222510096 1.342813339 1.23125705 0.963979807 0.888234065 1 9.154981172 VTQHES(ph)DNENEIQIQNK ddPTM_HeLa_Curcumin_4h_R1 4 VTQHESDNENEIQIQNK 17 0 Q5VZL5-2;Q5VZL5-4;Q5VZL5 Q5VZL5-2 ZMYM4 Zinc finger MYM-type protein 4 1 0 VT(0.008)QHES(0.992)DNENEIQIQNK;VT(0.034)QHES(0.966)DNENEIQIQNK;VT(0.013)QHES(0.987)DNENEIQIQNK;VT(0.072)QHES(0.928)DNENEIQIQNK ;;; 216.16 8.20E-16 189052800 13673.5 11402.4 11951.9 12623.1 11904.3 13759.6 10114 4178.09 13032.7 11832 TRUE FALSE FALSE 12591.22805 12387.97265 12394.84793 12570.86896 11762.349 10905.70386 10397.77162 5451.970407 11603.04542 12243.16112 1.028429498 1.011827953 1.012389513 1.026766603 0.960728106 0.890758829 0.849271811 0.445307413 0.947716468 1 13.57968848 -4.049759525 1.132653322 1.011548011 1.35E-23 0.954498782 0.035698074 0.270040667 0.204790023 0.004299116 0.362183699 8.92E-05 4.049759525 -1.011548011 down TSAVSS(ph)PLLDQQR ddPTM_HeLa_Curcumin_4h_R1 4 TSAVSSPLLDQQR 13 0 Q5T200-2;Q5T200;A0A087WX14 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 0 TSAVS(0.044)S(0.956)PLLDQQR;T(0.001)SAVS(0.164)S(0.836)PLLDQQR;TSAVS(0.001)S(0.999)PLLDQQR;TSAVS(0.029)S(0.971)PLLDQQR ;;; 234.52 6.81E-20 383907700 20991.6 16966.2 18919.6 18712.6 19922.7 23100.8 20534.9 8852.3 20978.4 18114.2 TRUE FALSE FALSE 19330.09271 18432.68273 19620.77702 18635.17222 19685.13481 18309.43368 21111.05403 11551.32552 18677.12201 18743.6671 1.0312866 0.983408563 1.046795001 0.994211651 1.050228576 0.976833059 1.126303296 0.616278845 0.996449729 1 14.19411562 -4.251966036 24.99270523 1.019132935 0.616278631 0.892341399 0.042346805 254.0945403 670342.0467 0.004998439 0.086215519 5.60E-05 4.251966036 -0.402854304 TSCSGSGERES(ph)PERK ddPTM_HeLa_Curcumin_4h_R1 1 TSCSGSGERESPERK 15 2 Q9H8Y5;C9JQZ3;C9K022 Q9H8Y5 ANKZF1 Ankyrin repeat and zinc finger domain-containing protein 1 1 0 T(0.001)S(0.001)CS(0.023)GS(0.105)GERES(0.869)PERK 48.229 0.019409 60351000 2104.5 2175.7 1826.3 1542.1 1613.8 2087.3 1468.7 856.01 1951.5 1967.8 TRUE FALSE FALSE 1937.926604 2363.757813 1893.984285 1535.719199 1594.556489 1654.370451 1509.907769 1117.003508 1737.425332 2036.180904 0.951745791 1.160878097 0.930165037 0.7542155 0.783111405 0.812486969 0.741539107 0.548577735 0.853276509 1 10.99165003 -6.306563395 3.599581222 0.992261937 0.733985895 0.631784067 0.096610258 0.107040993 2.878131842 0.013418654 0.021500103 4.94E-07 6.306563395 -0.258276042 TSDDEVGS(ph)PKEESR ddPTM_HeLa_Curcumin_4h_R1 1 TSDDEVGSPKEESR 14 1 Q6ULP2-7;Q6ULP2-8;Q6ULP2-6;Q6ULP2;Q6ULP2-9;B8ZZI9 Q6ULP2-7 AFTPH Aftiphilin 1 0 T(0.001)SDDEVGS(0.997)PKEES(0.001)R 65.298 0.017635 33700000 4735.6 4012.6 4079.2 4244 4736.7 5145.5 4720 6738.8 5341.4 4330.5 TRUE FALSE FALSE 4360.772263 4359.431264 4230.37874 4226.439453 4680.217946 4078.265298 4852.430497 8793.429098 4755.461784 4480.984553 0.973172795 0.972873531 0.944073493 0.943194381 1.044461968 0.91012706 1.082893824 1.962387729 1.061253778 1 12.12960004 -4.26294387 3.81259897 0.979882456 2.059843453 0.978246546 0.0436202 0.018235385 0.512696593 0.004529538 0.054887671 5.46E-05 4.26294387 1.079960997 TSDIFGS(ph)PVTATSR ddPTM_HeLa_Curcumin_4h_R1 3 TSDIFGSPVTATSR 14 0 A6NGP5;Q9H910;Q9H910-3;H3BU16;Q9H910-2;H3BMV3;H3BMT0;H3BTV5 A6NGP5 HN1L Hematological and neurological expressed 1-like protein 1 0 TSDIFGS(0.834)PVT(0.164)AT(0.002)SR;TSDIFGS(0.919)PVT(0.08)ATSR;T(0.02)S(0.002)DIFGS(0.83)PVT(0.136)AT(0.012)SR ;; 195.94 3.11E-06 453114500 8262.4 6416.8 6196.6 6865.7 6991.8 9368.8 7758 3767.47 8626.5 6395.8 TRUE FALSE FALSE 7608.422322 6971.439599 6426.251447 6837.291553 6908.427351 7425.605272 7975.6686 4916.15426 7680.194532 6618.053574 1.149646529 1.053397275 0.971018348 1.03312726 1.043876009 1.122022539 1.205138114 0.742839901 1.160491442 1 12.69219126 -6.998336817 24.9338629 1.07229039 1.032610256 0.065517678 0.120265258 206.9278386 3102082.003 0.019029077 0.024910722 1.00E-07 6.998336817 -0.039680135 TSDPDVILCNS(ph)VELIR ddPTM_HeLa_Curcumin_4h_R1 1 TSDPDVILCNSVELIR 16 0 Q96CW6;A0A087X0P9 Q96CW6 SLC7A6OS Probable RNA polymerase II nuclear localization protein SLC7A6OS 1 0 TSDPDVILCNS(1)VELIR 235.75 1.67E-22 17334000 2020.6 1530.9 1766.6 1440.8 1598.8 2234.7 1326.3 772.8 1627.5 1748.8 TRUE FALSE FALSE 1860.667378 1663.224174 1832.07175 1434.838351 1579.735354 1771.19803 1363.512408 1008.423162 1448.967322 1809.57067 1.028236923 0.9191264 1.012434485 0.79291645 0.872989036 0.978794616 0.753500502 0.557272053 0.800724363 1 10.82143174 -3.591652749 0.48738373 1.006476889 1.11E-24 0.509819806 0.098658895 2.810665803 0.281437829 0.015653367 1.874302688 0.000256063 3.591652749 -1.006476889 KESSVK(ac)TVR ddPTM_HeLa_Curcumin_4h_R1 2 KESSVKTVR 9 2 O95696-2;O95696;J3KQ61 O95696-2 BRD1 Bromodomain-containing protein 1 0 1 ; K(0.001)ESSVK(0.999)TVR;KESSVK(1)TVR 70.399 0.018121 12949700 3905.52 2941.6 3121.07 3325.1 2980.15 3829.3 2766.72 1032.82 3674.12 2937.62 FALSE TRUE FALSE 3596.393971 3195.858796 3236.7396 3311.341617 2944.613658 3035.060015 2844.346717 1347.722063 3271.078228 3039.702076 1.183140282 1.051372377 1.064821327 1.08936387 0.968717849 0.998472856 0.93573207 0.443373077 1.076118036 1 11.56971422 -4.084038928 1.447177562 1.075641093 5.07E-16 0.909876548 0.057396474 0.488737948 0.664182528 0.01120245 0.851750671 8.24E-05 4.084038928 -1.075641093 down TSDS(ph)PWFLSGSETLGR ddPTM_HeLa_Curcumin_4h_R1 1 TSDSPWFLSGSETLGR 16 0 E7EMW7;O95071-2;O95071 E7EMW7 UBR5 E3 ubiquitin-protein ligase UBR5 1 0 TSDS(1)PWFLSGSETLGR 205.66 2.04E-10 2901200 597.7 395.71 616.14 298.73 505.81 747.52 840.71 228.94 451.29 461.13 TRUE FALSE FALSE 550.3914143 429.9134092 638.9746904 297.4939344 499.7785461 592.4759257 864.2980599 298.7427521 401.7846161 477.1542332 1.153487439 0.900994645 1.339136585 0.623475417 1.047415094 1.241686408 1.811359933 0.626092637 0.842043491 1 8.898311862 -5.226542336 5.715532448 1.045273759 1.287912489 0.075627829 0.324558324 0.326233444 31.04443362 0.040412464 0.102954451 5.94E-06 5.226542336 0.24263873 TSDVNETQPPQS(ph)E ddPTM_HeLa_Curcumin_4h_R1 1 TSDVNETQPPQSE 13 0 P35580;P35580-5;P35580-2;P35580-3;P35580-4 P35580 MYH10 Myosin-10 1 0 TSDVNETQPPQS(1)E 88.056 0.014326 5660500 1645.6 1528.6 1421.5 1596.1 1536.5 1693.1 1625.9 897.55 1448.4 1391 TRUE FALSE FALSE 1515.349024 1660.725373 1474.18204 1589.495761 1518.178241 1341.931975 1671.518378 1171.208863 1289.514144 1439.337146 1.052810335 1.153812626 1.024208987 1.104324838 1.054775974 0.932326369 1.16131122 0.813714053 0.895908333 1 10.49118885 -4.240566066 24.18260039 1.041871912 0.813713701 0.414474785 0.081457867 2038.166525 2361245.288 0.008858347 0.495672837 5.75E-05 4.240566066 -0.228158211 TSEEDTPK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 TSEEDTPKK 9 1 A0A1B0GW41;Q8WYH8-2;Q8WYH8 A0A1B0GW41 ING5 Inhibitor of growth protein 5 0 1 ; TSEEDTPK(1)K;TSEEDTPK(1)K 191.17 2.31E-21 5818400 6248.3 5158.3 5356.6 4579.2 5010.6 5310.4 3368.5 2779.1 5293.6 4719 FALSE TRUE FALSE 5753.740462 5604.160467 5555.120308 4560.252484 4950.851868 4208.963179 3463.011044 3626.434797 4712.905324 4882.984899 1.178324443 1.147691542 1.137648472 0.933906735 1.013898664 0.861965226 0.709199622 0.742667625 0.965168933 1 12.2535476 -5.20093925 1.070367287 1.092160604 0.693473511 0.760962987 0.075519714 0.233152353 0.444293256 0.013135242 0.071715238 6.30E-06 5.20093925 -0.398687093 TSET(ph)SISPPGSSIGSPNR ddPTM_HeLa_Curcumin_4h_R1 1 TSETSISPPGSSIGSPNR 18 0 A0A0C4DGA7;O94929-2;O94929-3;O94929 A0A0C4DGA7 ABLIM3 Actin-binding LIM protein 3 1 0 TSET(0.429)S(0.429)IS(0.141)PPGSSIGSPNR 233.84 1.70E-23 21619000 1518.9 1214.3 1225.7 1433 1354.7 1603.8 1063.3 1238.2 1215.4 1398.3 TRUE FALSE FALSE 1398.677462 1319.258681 1271.12552 1427.070626 1338.546087 1271.153801 1093.133336 1615.72148 1082.073661 1446.890821 0.966677957 0.911788687 0.878522071 0.986301527 0.925118929 0.878541617 0.75550506 1.116685141 0.747861307 1 10.49874035 -7.480209746 1.969563479 0.987912707 0.914473651 0 0.114930016 0.465174142 3.547920809 0.015361672 0.016794277 3.31E-08 7.480209746 -0.073439056 TSETDDGVVGKS(ph)SDGEDEQQVPK ddPTM_HeLa_Curcumin_4h_R1 3 TSETDDGVVGKSSDGEDEQQVPK 23 1 Q16649 Q16649 NFIL3 Nuclear factor interleukin-3-regulated protein 1 0 TSETDDGVVGKS(0.919)S(0.081)DGEDEQQVPK;T(0.002)S(0.001)ET(0.005)DDGVVGKS(0.905)S(0.088)DGEDEQQVPK;TSET(0.002)DDGVVGKS(0.876)S(0.121)DGEDEQQVPK ;; 79.029 0.00025646 35456400 8879.88 6470.09 8052.68 8414.17 7649.88 10201.1 7345.84 3615.42 9390.9 7103.88 TRUE FALSE FALSE 8177.028128 7029.335749 8351.119405 8379.354394 7558.660177 8085.27687 7551.9445 4717.744915 8360.741765 7350.739301 1.112408942 0.956276024 1.136092448 1.139933556 1.028285709 1.099927033 1.027372104 0.6418055 1.137401481 1 12.84367364 -4.263349855 4.37817276 1.060258518 0.612487496 0.81412517 0.06151079 0.063893256 2.943572446 0.008449054 0.088255131 5.45E-05 4.263349855 -0.447771022 TSETSIS(ph)PPGSSIGSPNR ddPTM_HeLa_Curcumin_4h_R1 1 TSETSISPPGSSIGSPNR 18 0 A0A0C4DGA7;O94929-2;O94929-3;O94929 A0A0C4DGA7 ABLIM3 Actin-binding LIM protein 3 1 0 TSETS(0.005)IS(0.892)PPGS(0.079)S(0.024)IGSPNR 152.94 6.31E-05 30399000 3671.3 2824.5 2557.5 3318.3 3245.7 3344.1 3051.3 2293.5 3126 2838.3 TRUE FALSE FALSE 3380.712731 3068.637194 2652.2832 3304.569754 3206.997147 2650.495964 3136.911266 2992.777592 2783.085621 2936.930714 1.151104013 1.04484494 0.903079936 1.125177975 1.09195533 0.902471397 1.068091682 1.019015388 0.947617051 1 11.52009352 -7.001589895 24.99941063 1.072755717 1.019374856 0 0.08550915 129.3348165 2033691.545 0.013805493 0.0180017 9.96E-08 7.001589895 -0.053380861 TSEVNCYR ddPTM_HeLa_Curcumin_4h_R1 1 TSEVNCYR 8 0 P62633-7;P62633-3;P62633-2;P62633-8;P62633-5;P62633;P62633-4;P62633-6 P62633-7 CNBP Cellular nucleic acid-binding protein 0 0 93.429 0.019427 2202000 383.18 359.11 434.77 358.29 377.52 437.84 362.06 397.28 314.57 350.32 FALSE FALSE TRUE 352.8508987 390.1498682 450.8829587 356.8074909 373.0183206 347.0270485 372.2184292 518.4088431 280.062458 362.4935939 0.973398991 1.076294519 1.243837039 0.984313921 1.029034242 0.957332914 1.026827606 1.430118633 0.772599744 1 8.501811689 -4.262319938 5.845262026 1.012310269 1.442324099 0.571133987 0.109962578 0.058187362 8.90269062 0.011533948 0.0992697 5.47E-05 4.262319938 0.43001383 TISINS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 TISINSPK 8 0 A0A0J9YX88;E9PJ24;B7ZM65;F8WEF5;A0A0J9YYB5;A0A0J9YWD5;Q9P1Y6-2;Q9P1Y6-3;Q9P1Y6 A0A0J9YX88 PHRF1 PHD and RING finger domain-containing protein 1 1 0 T(0.001)ISINS(0.999)PK 132.32 0.0048068 11769000 6479.5 5614.4 5467.7 6077 5399.4 6561.3 5515.3 1985 6737.8 5827.7 TRUE FALSE FALSE 5966.640738 6099.683719 5670.337772 6051.854984 5335.015681 5200.412419 5670.044474 2590.217362 5998.680197 6030.212141 0.98945785 1.011520586 0.940321441 1.003589068 0.884714427 0.862392947 0.940272803 0.429540006 0.994771006 1 12.55799304 -4.04840298 1.797845954 0.980058301 3.32E-24 0.895072244 0.053820394 0.38284396 0.772992676 0.007836734 0.758888819 8.95E-05 4.04840298 -0.980058301 down TSFFQALGITTK ddPTM_HeLa_Curcumin_4h_R1 1 TSFFQALGITTK 12 0 F8VWS0;P05388-2;Q8NHW5;P05388;G3V210;F8VU65;F8VPE8;F8VW21 F8VWS0 RPLP0;RPLP0P6 60S acidic ribosomal protein P0;60S acidic ribosomal protein P0-like 0 0 191.79 5.41E-14 1465300 2046 1222.2 1779.5 1612.1 1508.9 2016.1 1923.1 2056.3 1711.9 1718.7 FALSE FALSE TRUE 1884.056941 1327.841522 1845.449835 1605.429557 1490.907353 1597.938134 1977.05701 2683.256404 1524.108853 1778.424697 1.059396523 0.74663916 1.037687926 0.902725631 0.838330324 0.898513238 1.111690033 1.508782693 0.856999374 1 10.79638417 -4.308602293 2.978616566 0.980040827 1.568275924 0.720363025 0.106639398 0.145967964 1.9635803 0.015135106 0.191622918 4.91E-05 4.308602293 0.588235097 TSFSQEQSCDS(ph)AGEGSER ddPTM_HeLa_Curcumin_4h_R1 3 TSFSQEQSCDSAGEGSER 18 0 Q1RLN5;Q8IWW6-3;Q8IWW6-2;Q8IWW6-4;Q8IWW6 Q1RLN5 ARHGAP12 Rho GTPase-activating protein 12 1 0 TSFSQEQS(0.006)CDS(0.994)AGEGSER;TSFSQEQS(0.001)CDS(0.999)AGEGSER;TSFSQEQS(0.046)CDS(0.954)AGEGSER ;; 279.5 3.51E-67 21032200 2897.94 2381.48 2862.88 2781.5 2562.33 3161.99 2001.18 1277.05 3247.41 2721.49 TRUE FALSE FALSE 2668.564991 2587.32452 2968.980851 2769.99089 2531.775888 2506.157631 2057.327725 1666.416666 2891.177248 2816.061575 0.947623097 0.918774129 1.054302533 0.983640029 0.899048483 0.88995129 0.730569155 0.591754343 1.026674016 1 11.45946316 -4.467195374 1.038416663 0.976365904 0.465906499 0.910488268 0.040485892 0.265863224 0.280437934 0.006040839 0.137614464 3.41E-05 4.467195374 -0.510459405 TSFSVGS(ph)DDELGPIR ddPTM_HeLa_Curcumin_4h_R1 2 TSFSVGSDDELGPIR 15 0 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 0 TSFS(0.008)VGS(0.992)DDELGPIR;TSFSVGS(1)DDELGPIR ; 191.63 2.36E-06 389330000 2492.7 1859.38 2503.95 2440 2268.38 2870.9 1908.37 1539.25 2782.8 2404.3 TRUE FALSE FALSE 2295.400165 2020.096522 2596.74859 2429.903927 2241.33105 2275.442978 1961.913726 2008.560239 2477.533802 2487.849246 0.922644396 0.811985101 1.043772485 0.976708669 0.90091112 0.914622533 0.788598316 0.807348051 0.99585367 1 11.28068335 -2.33895969 0.381026626 0.965850817 1.01E-17 0.453500451 0.062976902 14.93335109 0.47137485 0.017121955 9.078258114 0.004581844 2.33895969 -0.965850817 TSFSVGS(ph)DDELGPIRK ddPTM_HeLa_Curcumin_4h_R1 3 TSFSVGSDDELGPIRK 16 1 Q9NRY4 Q9NRY4 ARHGAP35 Rho GTPase-activating protein 35 1 0 TSFS(0.034)VGS(0.966)DDELGPIRK;TSFS(0.002)VGS(0.998)DDELGPIRK;TSFS(0.007)VGS(0.993)DDELGPIRK ;; 148.18 6.68E-08 36626000 2888.02 2471.31 2265.9 2965.21 2588.22 2952.78 2073.06 1789.47 2924.06 2804.17 TRUE FALSE FALSE 2659.43017 2684.919024 2349.876247 2952.940747 2557.357167 2340.340143 2131.224484 2335.071165 2603.297934 2901.614699 0.916534566 0.925318936 0.809851235 1.017688788 0.881356566 0.806564753 0.734496033 0.804748875 0.897189394 1 11.50264024 -1 0.16318693 1.011930653 2.74E-09 0.425313848 0.065295303 31.35776222 0.321225577 0.100121938 7.703133119 0.1 1 -1.01193065 TSGAPGS(ph)PQTPPER ddPTM_HeLa_Curcumin_4h_R1 2 TSGAPGSPQTPPER 14 0 K7ESM2;K7ELS4;K7EJA3;K7ERG7;Q96MH2;K7EIM4 K7ESM2 HEXIM2 Protein HEXIM2 1 0 TSGAPGS(0.997)PQT(0.003)PPER;TSGAPGS(0.948)PQT(0.052)PPER ; 130.66 0.0010705 36139000 7310.6 6564.5 7457.9 7419.6 7407.5 8257.4 5912 4594.5 7001.4 6352 TRUE FALSE FALSE 6731.958296 7131.906129 7734.296335 7388.899661 7319.1704 6544.72216 6077.874809 5995.3419 6233.363937 6572.731527 1.024225357 1.085074919 1.176724822 1.124174878 1.113566007 0.99573855 0.924710645 0.912153779 0.948367343 1 12.68227734 -4.881538293 3.533172466 1.044908247 0.917009962 0.432736972 0.064858285 0.202595402 4.830926468 0.010171303 0.035389275 1.31E-05 4.881538293 -0.127898285 TSGGDHAPDS(ph)PSGENSPAPQGR ddPTM_HeLa_Curcumin_4h_R1 1 TSGGDHAPDSPSGENSPAPQGR 22 0 E9PL60;E9PII7;H0YDE3;H0YDU2;E9PRI1;Q96NY9 E9PL60 MUS81 Crossover junction endonuclease MUS81 1 0 TSGGDHAPDS(0.864)PS(0.113)GENS(0.022)PAPQGR 58.319 0.005516 5737800 1646.2 1252.1 1224.7 1222.6 1856.1 2743.2 1391.7 999.77 1639.2 1596.4 TRUE FALSE FALSE 1515.901533 1360.325945 1270.088459 1217.541205 1833.96722 2174.229398 1430.747356 1304.595271 1459.383861 1651.874781 0.917685499 0.823504275 0.76887696 0.737066283 1.110233803 1.316219257 0.86613548 0.789766443 0.88347124 1 10.68988861 -4.530571131 24.99283262 0.955311655 0.808858495 0.081788404 0.162159064 282.4369347 917651.8712 0.023339316 0.087666798 2.95E-05 4.530571131 -0.14645316 TSGGDHAPDSPS(ph)GENSPAPQGR ddPTM_HeLa_Curcumin_4h_R1 1 TSGGDHAPDSPSGENSPAPQGR 22 0 E9PL60;E9PII7;H0YDE3;H0YDU2;E9PRI1;Q96NY9 E9PL60 MUS81 Crossover junction endonuclease MUS81 1 0 TSGGDHAPDS(0.412)PS(0.49)GENS(0.098)PAPQGR 71.524 0.0010296 6097100 2906.4 1992.2 2136.2 2029.7 2522.1 4592.4 3022.8 1440.7 3725.9 2026.8 TRUE FALSE FALSE 2676.355373 2164.396891 2215.369451 2021.301639 2492.025605 3639.884473 3107.611633 1879.962798 3317.178092 2097.231149 1.276137527 1.032025913 1.056330606 0.963795355 1.188245562 1.735566666 1.481768776 0.896402287 1.581694079 1 11.03427016 -5.506429566 24.84558562 1.107346563 1.395566199 0.112080481 0.258088712 686.0150757 1036187.032 0.030836836 0.067276496 3.12E-06 5.506429566 0.288219637 TSGNS(ph)FKVNS(ph)CK ddPTM_HeLa_Curcumin_4h_R1 1 TSGNSFKVNSCK 12 1 A0A590UJI7;P51587 A0A590UJI7 BRCA2 Breast cancer type 2 susceptibility protein 2 0 T(0.018)S(0.018)GNS(0.965)FKVNS(1)CK 85.731 0.0095585 0 1044.9 942.96 723.17 900.03 1014.4 1098.4 632.53 680.64 1101.9 796.42 TRUE FALSE FALSE 962.1950624 1024.465261 749.9713164 896.3059143 1002.303943 870.5794585 650.2770894 888.1640027 981.0243268 824.0955357 1.167577084 1.243138952 0.910053852 1.087623795 1.216247266 1.056405988 0.789079738 1.07774398 1.190425484 1 9.686667786 -4.976728557 24.20152079 1.090760172 0.930744394 0.258193299 0.117209252 171.0057793 177837.0057 0.016052409 0.048152516 1.06E-05 4.976728557 -0.160015779 TSGSEMANK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 TSGSEMANKR 10 1 Q86T24 Q86T24 ZBTB33 Transcriptional regulator Kaiso 0 1 ; TSGSEMANK(1)R;TSGSEMANK(1)R 144.65 5.10E-06 3952500 1571.36 1352.81 1584.31 1437.57 1593.24 1855.18 1497.64 554.05 1240.59 1297.47 FALSE TRUE FALSE 1446.985198 1469.740868 1643.025922 1431.621716 1574.241654 1470.394756 1539.659748 722.9772945 1104.500381 1342.556986 1.077783076 1.094732577 1.223803488 1.066339627 1.172569708 1.095219623 1.146811468 0.538507715 0.822684171 1 10.39076761 -4.256699489 24.99840651 1.0741865 0.538507497 0.709652301 0.103457722 157.1134141 828595.0405 0.010805328 0.117533241 5.54E-05 4.256699489 -0.535679002 TSIDAYDNFDNISLAQR ddPTM_HeLa_Curcumin_4h_R1 1 TSIDAYDNFDNISLAQR 17 0 A0A087WVQ6;Q00610-2;Q00610;J3KS13;K7EJJ5 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 168.67 0.00068144 6897200 1251.5 1106.1 880.4 1060.9 1081.9 1237.8 1043.4 1091.2 1240.3 1103.3 FALSE FALSE TRUE 1152.442454 1201.706355 913.0283985 1056.510277 1068.999049 981.0663271 1072.674996 1423.901857 1104.242193 1141.639593 1.009462585 1.05261447 0.799751869 0.925432407 0.936371737 0.859348549 0.939591621 1.247242883 0.967242377 1 10.15689156 TSISDPPES(ph)PPLLPPREPVR ddPTM_HeLa_Curcumin_4h_R1 1 TSISDPPESPPLLPPREPVR 20 1 G5E9C8;Q07889 G5E9C8 SOS1 Son of sevenless homolog 1 1 0 T(0.002)S(0.001)IS(0.015)DPPES(0.983)PPLLPPREPVR 58.635 0.0082872 14897000 2134.5 1509.6 1678.3 1623.9 1724.9 2083.1 2091.7 1579.8 1849.5 1821.6 TRUE FALSE FALSE 1965.552073 1640.083097 1740.499274 1617.180732 1704.331694 1651.041579 2150.387472 2061.473747 1646.614477 1884.900464 1.042788258 0.870116554 0.923390549 0.857966117 0.90420249 0.875930379 1.140849352 1.093677776 0.87358166 1 10.88027263 -4.740710739 24.99604615 0.975369327 1.117263671 0.386999701 0.076903576 229.5164643 276762.5956 0.012010428 0.044837628 1.82E-05 4.740710739 0.141894344 TSKEPPSS(ph)PLQPQK ddPTM_HeLa_Curcumin_4h_R1 2 TSKEPPSSPLQPQK 14 1 A0A087X183;H0Y4V9;Q92615 A0A087X183 LARP4B La-related protein 4B 1 0 T(0.005)S(0.001)KEPPS(0.038)S(0.956)PLQPQK;TSKEPPS(0.005)S(0.994)PLQPQK ; 94.61 0.0033507 147699000 10510.5 8884.8 9874.7 9562.6 11664.1 13601.6 11981.7 6533.9 10693.5 9271.4 TRUE FALSE FALSE 9678.582834 9652.762522 10240.66507 9523.032495 11525.01323 10780.47484 12317.87425 8526.056032 9520.449804 9593.58046 1.008860339 1.006168923 1.067449751 0.992646336 1.20132554 1.123717561 1.283970495 0.888725129 0.992377126 1 13.22785363 -5.77573057 24.88734201 1.008997903 1.135778876 0.248179387 0.095649044 189.8824144 330669.9085 0.012496127 0.022729042 1.68E-06 5.77573057 0.126780974 TSLAGDTS(ph)NSS(ph)SPASTGAK ddPTM_HeLa_Curcumin_4h_R1 1 TSLAGDTSNSSSPASTGAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 2 0 T(0.027)S(0.01)LAGDT(0.114)S(0.835)NS(0.065)S(0.522)S(0.422)PAS(0.004)T(0.001)GAK 102.69 0.00082892 0 2316.1 1927 2077.6 2277 2183.8 4135.5 3431.1 1301.2 2655 2105.5 TRUE FALSE FALSE 2132.778241 2093.561293 2154.597684 2267.578377 2157.759611 3277.750683 3527.367432 1697.92989 2363.753142 2178.665968 0.978937695 0.960937254 0.988952742 1.040810482 0.990404056 1.50447601 1.619049218 0.779343835 1.084954361 1 11.0892293 -5.281925835 23.29060638 0.99144021 1.33276561 0.292218843 0.207380822 236.0480042 268357.7419 0.026562468 0.059482468 5.22E-06 5.281925835 0.3413254 TSLAGDTSNSSS(ph)PASTGAK ddPTM_HeLa_Curcumin_4h_R1 1 TSLAGDTSNSSSPASTGAK 19 0 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3;H0Y6T5;H0Y4F5;H0Y314 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 1 0 TSLAGDTSNSS(0.004)S(0.996)PASTGAK 161.48 1.70E-05 12953000 3679.6 3182.9 3379 3259.6 3167.3 5407 4949.9 1729.5 3863.3 2899 TRUE FALSE FALSE 3388.355777 3458.015693 3504.228712 3246.112639 3129.532016 4285.527251 5088.780872 2256.816588 3439.505656 2999.740034 1.129549807 1.152771791 1.168177466 1.082131319 1.043267743 1.428632882 1.696407293 0.75233739 1.146601244 1 11.55062176 -7.017246911 0.301417854 0.992779273 1.298772452 0.026572524 0.236090145 2.545882574 0.700754654 0.209561679 0.298317218 9.61E-08 7.017246911 0.305993179 TSLDIEEYS(ph)DTEVQK ddPTM_HeLa_Curcumin_4h_R1 3 TSLDIEEYSDTEVQK 15 0 P51580 P51580 TPMT Thiopurine S-methyltransferase 1 0 TSLDIEEYS(0.99)DT(0.01)EVQK;TSLDIEEYS(0.839)DT(0.161)EVQK;T(0.003)S(0.002)LDIEEYS(0.547)DT(0.448)EVQK ;; 230.86 4.38E-54 42999000 9662.5 8000.7 8468.4 9574.6 8176.2 10392 8164.5 6695.1 9221.2 8040.4 TRUE FALSE FALSE 8897.702929 8692.244858 8782.246354 9534.982842 8078.704155 8236.582058 8393.573896 8736.40517 8209.65743 8319.803302 1.069460732 1.044765668 1.055583412 1.146058686 0.971021052 0.98999721 1.008866868 1.050073524 0.986761001 1 13.0223337 DTTKLEPAS(ph)PPEDTSAEVSR ddPTM_HeLa_Curcumin_4h_R1 3 DTTKLEPASPPEDTSAEVSR 20 1 E9PFE2;Q9UHL9-2;Q9UHL9;Q9UHL9-3 E9PFE2 GTF2IRD1 General transcription factor II-I repeat domain-containing protein 1 1 0 DT(0.001)T(0.001)KLEPAS(0.993)PPEDT(0.002)S(0.002)AEVSR;DTTKLEPAS(1)PPEDTSAEVSR;DT(0.001)T(0.007)KLEPAS(0.717)PPEDT(0.186)S(0.083)AEVS(0.005)R ;; 112.28 8.89E-05 115454000 8899.2 7188.6 7902.5 7862.5 6866.3 9082 6399 2441.93 9956 8279.1 TRUE FALSE FALSE 8194.81893 7809.950552 8195.373602 7829.967058 6784.423857 7198.290825 6578.538718 3186.463216 8863.851709 8566.798109 0.956578972 0.911653392 0.956643719 0.913989913 0.791943941 0.840254519 0.767911025 0.37195498 1.034674985 1 13.06454037 -4.047339438 0.713120343 0.969157234 1.37E-33 0.881002201 0.062260921 0.829749287 0.240898309 0.00986062 0.692061221 8.97E-05 4.047339438 -0.969157234 down TSLPLS(ph)PVKTAPLFSNDR ddPTM_HeLa_Curcumin_4h_R1 1 TSLPLSPVKTAPLFSNDR 18 1 Q86XL3;Q86XL3-2 Q86XL3 ANKLE2 Ankyrin repeat and LEM domain-containing protein 2 1 0 TSLPLS(0.997)PVKT(0.002)APLFSNDR 78.95 0.00342 0 650.74 509.84 460.75 562.01 348.51 654.28 514.7 537.29 864.58 560.67 TRUE FALSE FALSE 599.2332423 553.9082978 477.8258003 559.6845515 344.3542459 518.5749527 529.1410968 701.1072476 769.7377371 580.1532408 1.032887865 0.954762051 0.82361998 0.964718478 0.593557394 0.893858581 0.912071259 1.208486307 1.326783482 1 9.180290212 -7.001864647 5.394032267 1.014763723 0.888429838 0.175904956 0.172615838 0.249049774 23.76207074 0.022753919 0.02916343 9.96E-08 7.001864647 -0.126333884 TSLS(ph)FQDPK ddPTM_HeLa_Curcumin_4h_R1 2 TSLSFQDPK 9 0 P48681 P48681 NES Nestin 1 0 TSLS(1)FQDPK;T(0.008)S(0.004)LS(0.988)FQDPK ; 117.14 0.006977 28377000 8744.1 7754.7 9414.4 8873.8 9505.2 11681.7 7377.2 5079.7 8357.9 7205.8 TRUE FALSE FALSE 8051.995258 8424.981714 9763.305946 8837.082567 9391.856698 9258.78374 7584.184377 6628.477146 7441.05928 7456.201014 1.079905872 1.129929531 1.309420968 1.185199078 1.259603474 1.241756187 1.017164688 0.888988526 0.997969243 1 12.86422504 -7.67421885 1.456217013 1.024766782 1.156733599 0.191629853 0.116734422 0.462951236 2.026119769 0.026364894 0.026265302 2.12E-08 7.67421885 0.131966818 TSLS(ph)FQDPKLELQFPR ddPTM_HeLa_Curcumin_4h_R1 1 TSLSFQDPKLELQFPR 16 1 P48681 P48681 NES Nestin 1 0 T(0.013)S(0.013)LS(0.973)FQDPKLELQFPR 81.128 0.0051796 26689000 2646.6 2406.2 2572.9 2386.1 2050.9 3526.5 1879.2 1852.2 3422.6 2818.3 TRUE FALSE FALSE 2437.118817 2614.181206 2668.253937 2376.22695 2026.444357 2795.064148 1931.925294 2416.927254 3047.149343 2916.235715 0.835707074 0.89642315 0.914965112 0.814826778 0.694883595 0.958449323 0.66247227 0.828783229 1.044891305 1 11.50989162 -13.52287875 0.119578095 1.616586643 0.721753664 0.495328521 0.083285863 61.2565481 0.529411667 9.113173273 0.373120878 3.00E-14 13.52287875 -0.89483298 TSLS(ph)PTSK ddPTM_HeLa_Curcumin_4h_R1 1 TSLSPTSK 8 0 Q8NDI1-3;Q8NDI1-2;Q8NDI1;H7C0Q4 Q8NDI1-3 EHBP1 EH domain-binding protein 1 1 0 T(0.218)S(0.028)LS(0.508)PT(0.246)SK 99.815 0.015161 22583000 7031.3 5832.8 6237 6554.3 6209.8 8227.7 7443 8352.7 7245.4 6979.6 TRUE FALSE FALSE 6474.765186 6336.961242 6468.148707 6527.180043 6135.752191 6521.182275 7651.830548 10899.39978 6450.597747 7222.14058 0.896516083 0.877435321 0.895599945 0.903773607 0.849575292 0.902943137 1.059496207 1.509164722 0.893169785 1 12.81821079 -4.275502507 2.602966389 0.927973343 1.619176747 0.945489236 0.043531144 0.099578743 0.882260918 0.008131611 0.147609627 5.30E-05 4.275502507 0.691203404 TSMPS(ph)GDESIDEK ddPTM_HeLa_Curcumin_4h_R1 1 TSMPSGDESIDEK 13 0 Q03468 Q03468 ERCC6 DNA excision repair protein ERCC-6 1 0 T(0.005)S(0.014)MPS(0.979)GDES(0.002)IDEK 96.707 0.010181 5875600 2884.2 2331.2 2499.1 3071.9 2673.9 2513.3 2218.1 1616.5 3077.1 2498.8 TRUE FALSE FALSE 2655.912527 2532.69854 2591.718844 3059.189292 2642.015489 1992.013249 2280.333916 2109.363409 2739.549829 2585.633114 1.027180737 0.979527423 1.002353671 1.183149023 1.021806023 0.77041605 0.88192478 0.815801514 1.05952767 1 11.33630186 -5.272789732 24.2727817 1.023361387 0.828635184 0.727371691 0.060132809 197.2239339 421764.6149 0.008490004 0.019156026 5.34E-06 5.272789732 -0.194726203 ARS(ph)DDYLSR ddPTM_HeLa_Curcumin_4h_R1 1 ARSDDYLSR 9 1 Q9P227-2;Q9P227 Q9P227-2 ARHGAP23 Rho GTPase-activating protein 23 1 0 ARS(1)DDYLSR 127.52 0.0011071 0 2331.7 2182 2072.3 2167.9 2062.9 2677.3 1926.9 766.36 2382.7 2159.6 TRUE FALSE FALSE 2147.143485 2370.602357 2149.101261 2158.929804 2038.301265 2121.997801 1980.963628 1000.019636 2121.323771 2234.645939 0.96084281 1.06084025 0.961718912 0.966117167 0.912136115 0.949590163 0.886477626 0.447506971 0.949288536 1 11.12583055 -4.046679801 1.711582201 0.979436312 3.94E-14 0.944055408 0.037905281 0.273952393 0.495900494 0.005410823 0.520048328 8.98E-05 4.046679801 -0.979436312 down TSNTLEKDLDLLASVPS(ph)PSSSGSR ddPTM_HeLa_Curcumin_4h_R1 2 TSNTLEKDLDLLASVPSPSSSGSR 24 1 A0A087WV97;Q8WU79-3;Q8WU79-2;Q8WU79 A0A087WV97 SMAP2 Stromal membrane-associated protein 2 1 0 TSNTLEKDLDLLAS(0.325)VPS(0.554)PS(0.114)S(0.005)S(0.002)GSR;TSNTLEKDLDLLAS(0.006)VPS(0.521)PS(0.17)S(0.17)S(0.076)GS(0.058)R ; 109.48 1.18E-06 88536000 5582 3632.2 3283.4 4664 3146.5 6156.5 4625.4 2760.1 6696.2 4458.8 TRUE FALSE FALSE 5140.17881 3946.151183 3405.085692 4644.701604 3108.980043 4879.572502 4755.176275 3601.641784 5961.643613 4613.742968 1.114101684 0.855303646 0.738031077 1.006710091 0.673852025 1.057616893 1.030654787 0.780633384 1.292149054 1 12.17172192 -7.254433588 24.41809733 1.053881351 0.882125786 0.366290193 0.143819964 365.8876573 1275270.795 0.020199405 0.024451812 5.57E-08 7.254433588 -0.171755565 TSPDTLRR ddPTM_HeLa_Curcumin_4h_R1 1 TSPDTLRR 8 1 J3KP15;Q01130;J3QL05;Q01130-2 J3KP15 SRSF2 Serine/arginine-rich splicing factor 2 0 0 115.49 0.014187 9553100 6881.4 6328.5 6845.8 6452.8 7136.1 8388.6 6527 7144.3 7050.2 5770.5 FALSE FALSE TRUE 6336.729929 6875.507341 7099.51137 6426.100023 7051.006668 6648.709801 6710.130053 9322.564182 6276.810699 5971.024445 1.06124669 1.151478679 1.188993854 1.076213987 1.180870508 1.113495659 1.123782044 1.561300622 1.05121169 1 12.54376276 -1.475947645 1.033148556 1.062143738 200 0.792839922 0.067392268 230.4456314 0.781280586 0.012006804 107937.6103 0.033423533 1.475947645 198.9378563 TSPPGGELS(ph)PGAGR ddPTM_HeLa_Curcumin_4h_R1 2 TSPPGGELSPGAGR 14 0 Q99958 Q99958 FOXC2 Forkhead box protein C2 1 0 TSPPGGELS(1)PGAGR;TSPPGGELS(1)PGAGR ; 125.47 0.0013339 92090000 2477 1505.49 1815.96 2171.2 1835.63 2024.67 1456.07 1925.74 2504 1800.88 TRUE FALSE FALSE 2280.942836 1635.617847 1883.261075 2162.21615 1813.741311 1604.730619 1496.923405 2512.889261 2229.317465 1863.460446 1.224036089 0.877731454 1.010625731 1.160323072 0.973318921 0.861156255 0.803303021 1.348506896 1.196332055 1 10.86376848 -7.261663875 24.99947534 1.105794817 0.996677813 0.11881111 0.159556367 39.81469932 4433643.998 0.027436526 0.032443885 5.47E-08 7.261663875 -0.109117004 TSPSGGTWSSVVSGVPRLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 TSPSGGTWSSVVSGVPRLSPK 21 1 H0YH87;A0A2R8Y7P6;A0A2R8YDM9;A0A5F9ZHH4;F8VQP2;V9GY86;A0A5F9ZI57;A0A2R8Y7E6;A0A2R8Y5A6;A0A5F9ZHX3;A0A5F9ZHW5;Q99700-2;Q99700-5;Q99700-4;Q99700 H0YH87 ATXN2 Ataxin-2 1 0 TSPSGGTWSSVVSGVPRLS(1)PK;TSPSGGTWSSVVSGVPRLS(1)PK ; 96.045 0.00012708 257840000 3252.2 2428.3 2349.3 2747.2 2443 2993.4 2032.95 1661.77 2624.6 2738.1 TRUE FALSE FALSE 2994.784938 2638.191432 2436.367125 2735.832814 2413.868821 2372.535097 2089.989106 2168.436023 2336.687946 2833.248771 1.057014466 0.931154178 0.859919944 0.965616871 0.851979129 0.837390321 0.73766523 0.765353203 0.824738008 1 11.46824157 -5.678209493 0.540884878 1.027918633 0.716156933 0.355981844 0.078238089 0.404430282 0.182394254 0.011788287 0.06145959 2.10E-06 5.678209493 -0.3117617 TSPVTASDPAGPSYAAATLQASSAASSAS(ph)PVSR ddPTM_HeLa_Curcumin_4h_R1 1 TSPVTASDPAGPSYAAATLQASSAASSASPVSR 33 0 F5H8D7;P18887;M0QYS5;M0R1U8 F5H8D7 XRCC1 DNA repair protein XRCC1 1 0 TSPVTASDPAGPSYAAATLQASSAAS(0.013)S(0.122)AS(0.676)PVS(0.188)R 93.055 7.82E-11 18402000 2321 1609.2 1824 2087.3 1672.6 2373.5 1882.6 526.64 2037.9 1596.4 TRUE FALSE FALSE 2137.290401 1748.292078 1891.599045 2078.663306 1652.655337 1881.209345 1935.420689 687.2101116 1814.347469 1651.874781 1.293857395 1.058368405 1.14512254 1.258366148 1.000472527 1.138832899 1.17165097 0.416018284 1.09835654 1 10.68988861 -4.259756128 24.95569103 1.136817274 0.416018038 0.842313671 0.092555107 50.16503291 743673.4705 0.016111545 0.137180609 5.50E-05 4.259756128 -0.720799235 AWLDEDSNLS(ph)PSPLRDLSGGLGGQEEEEEQR ddPTM_HeLa_Curcumin_4h_R1 2 AWLDEDSNLSPSPLRDLSGGLGGQEEEEEQR 31 1 Q9C086;B8ZZ93;B8ZZH7;F8WCL7;J3KQ70 Q9C086 INO80B;INO80B-WBP1 INO80 complex subunit B 1 0 AWLDEDS(0.095)NLS(0.448)PS(0.448)PLRDLS(0.009)GGLGGQEEEEEQR;AWLDEDS(0.158)NLS(0.457)PS(0.366)PLRDLS(0.019)GGLGGQEEEEEQR ; 71.118 3.94E-05 10796200 1213.56 854.05 942.18 1103.88 1042.8 1339.24 908.93 396.99 1308.46 1072.27 TRUE FALSE FALSE 1117.505445 927.8702764 977.0980196 1099.312437 1030.365291 1061.466528 934.4321295 518.0304235 1164.925212 1109.531303 1.007186947 0.836272284 0.880640336 0.990789926 0.928649141 0.956680109 0.84218636 0.46689122 1.049925503 1 10.11573465 -4.046187332 1.497220316 0.976320063 0.025717409 0.847798414 0.06186219 0.537436025 0.730552068 0.009491745 0.877421598 8.99E-05 4.046187332 -0.950602654 down TSQLGDS(ph)PFYPGK ddPTM_HeLa_Curcumin_4h_R1 2 TSQLGDSPFYPGK 13 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 0 T(0.001)S(0.006)QLGDS(0.993)PFY(0.001)PGK;TSQLGDS(0.968)PFY(0.032)PGK ; 115.1 0.0029587 74302000 10518.6 8894 9454.7 9244.4 9953.1 16400.9 14343.2 4669.8 11757.4 8307.3 TRUE FALSE FALSE 9686.041711 9662.757729 9805.099499 9206.149122 9834.415783 12999.16846 14745.63159 6093.600523 10467.64264 8595.978057 1.126810893 1.124102187 1.140661299 1.070983321 1.144071765 1.512238442 1.715410567 0.708889725 1.217737245 1 13.06944608 -5.447304643 6.154531768 1.075196916 1.351604363 0.098920329 0.246319444 0.261543217 16.94241897 0.031930279 0.071736429 3.57E-06 5.447304643 0.276407447 TSQVGAASAPAKES(ph)PR ddPTM_HeLa_Curcumin_4h_R1 4 TSQVGAASAPAKESPR 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR;TSQVGAASAPAKES(1)PR ;;; 222.93 8.39E-15 4220700000 26188.6 22166.7 23080.7 23798.1 23803.2 29730.9 24399.1 17669.4 27455.3 23601 TRUE FALSE FALSE 24115.74468 24082.69078 23936.09105 23699.62977 23519.36239 23564.3762 25083.67308 23056.71872 24443.52228 24421.13299 0.987494916 0.98614142 0.980138434 0.970455784 0.96307417 0.964917402 1.027129785 0.944129772 1.0009168 1 14.57584251 -7.699082339 0.659094035 0.998066843 0.976056367 0.192210994 0.020066645 0.828972416 0.808176123 0.006516105 0.005618329 2.00E-08 7.699082339 -0.022010476 TSQVGAASAPAKES(ph)PRK ddPTM_HeLa_Curcumin_4h_R1 1 TSQVGAASAPAKESPRK 17 2 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 TSQVGAAS(0.004)APAKES(0.996)PRK 71.527 0.012911 64440000 1132.8 1206.7 985.26 1284.6 1430.6 1336 1336.5 976.45 1319.7 1102.3 TRUE FALSE FALSE 1043.137685 1311.001771 1021.774602 1279.284666 1413.541029 1058.89854 1373.998593 1274.16511 1174.932212 1140.604843 0.914547831 1.149391728 0.895818222 1.121584459 1.239290748 0.928365811 1.204622794 1.117096002 1.030095759 1 10.15558335 -6.240211174 22.88619652 0.971520062 1.122508877 0.254122556 0.101468982 227.8514309 245646.5358 0.014368108 0.023803711 5.75E-07 6.240211174 0.150988815 TSQVGAASAPAKESPR ddPTM_HeLa_Curcumin_4h_R1 1 TSQVGAASAPAKESPR 16 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 0 0 176.42 1.98E-05 3921100 2079.1 1447 1711.8 1635.4 1661.2 1831.2 1598.4 1128.1 1769.6 1894.2 FALSE FALSE TRUE 1914.537041 1572.072232 1775.240814 1628.633148 1641.391275 1451.388478 1643.246802 1472.052497 1575.479307 1960.023309 0.976792996 0.802068131 0.905724338 0.830925398 0.837434569 0.740495519 0.838381255 0.751038261 0.803806414 1 10.9366551 -6.944137996 0.658075255 1.001259172 0.784920327 0.13912384 0.076812441 0.205696196 0.186025163 0.011176325 0.01674586 1.14E-07 6.944137996 -0.216338846 TSRDTS(ph)PSSGSAVSSSK ddPTM_HeLa_Curcumin_4h_R1 3 TSRDTSPSSGSAVSSSK 17 1 F8WF16;B7Z8L1;F8W6A0;F8W0Q9;Q8NEY8-5;Q8NEY8-6;Q8NEY8-9;Q8NEY8-8;Q8NEY8-2;Q8NEY8-3;Q8NEY8;Q8NEY8-7 F8WF16 PPHLN1 Periphilin-1 1 0 T(0.001)S(0.003)RDT(0.071)S(0.925)PSSGSAVSSSK;T(0.001)S(0.001)RDT(0.196)S(0.8)PS(0.002)SGSAVSSSK;T(0.024)S(0.024)RDT(0.105)S(0.834)PS(0.012)S(0.001)GSAVSSSK ;; 91.565 0.0016498 23262100 9004.4 6003.71 5083.07 6767.61 3278.42 8314.2 4301.7 4059.83 13554.7 7893.1 TRUE FALSE FALSE 8291.692239 6522.64394 5271.453046 6739.607423 3239.326983 6589.7412 4422.394125 5297.653478 12067.78332 8167.384637 1.015220001 0.798620884 0.645427304 0.825185506 0.396617415 0.806836153 0.541470045 0.648635238 1.477557855 1 12.99565846 -7.026364804 2.049238001 1.009374414 0.639007085 0.570945639 0.18757288 0.121043583 1.002618992 0.018169515 0.023528364 9.41E-08 7.026364804 -0.370367329 TSRPENAIIYNNNEDFQVGQAK ddPTM_HeLa_Curcumin_4h_R1 1 TSRPENAIIYNNNEDFQVGQAK 22 1 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 0 208.87 1.02E-79 0 1584.6 1124.8 1357.8 1332.3 1415.2 1753.7 1303.8 1235.3 1855.5 1100.2 FALSE FALSE TRUE 1459.177238 1222.0227 1408.121262 1326.787296 1398.324664 1389.962852 1340.381119 1611.937283 1651.956292 1138.431868 1.281743141 1.073426293 1.236895507 1.165451647 1.228290163 1.220945136 1.177392479 1.415927759 1.451080507 1 10.15283224 -9.437903764 0.891994457 0.983403654 1.223016937 0 0.163175228 0.449770475 0.564614807 0.077456049 0.014720763 3.65E-10 9.437903764 0.239613284 TSS(ph)DDES(ph)EEDEDDLLQR ddPTM_HeLa_Curcumin_4h_R1 2 TSSDDESEEDEDDLLQR 17 0 Q9Y5J1 Q9Y5J1 UTP18 U3 small nucleolar RNA-associated protein 18 homolog 2 0 T(0.009)S(0.013)S(0.978)DDES(1)EEDEDDLLQR;T(0.005)S(0.005)S(0.99)DDES(1)EEDEDDLLQR ; 247.5 1.24E-30 17667600 6020 5947.7 6274.2 6760.3 4721.3 6119.8 5226.5 3770.52 6403.2 6515.9 TRUE FALSE FALSE 5543.510648 6461.792686 6506.727371 6732.32767 4665.001581 4850.484496 5373.141524 4920.134191 5700.78498 6742.32704 0.822195455 0.958392058 0.965056624 0.998516926 0.69189785 0.719408072 0.796926861 0.729738288 0.845521872 1 12.71903089 -5.756687083 24.99999302 0.926851329 0.737874848 0.718215155 0.060429114 63.56056275 334363.2579 0.011058911 0.021555523 1.75E-06 5.756687083 -0.188976481 TSS(ph)DPNLNNHCQEVR ddPTM_HeLa_Curcumin_4h_R1 2 TSSDPNLNNHCQEVR 15 0 J3QR65;Q9NYA4 J3QR65 MTMR4 Myotubularin-related protein 4 1 0 T(0.16)S(0.16)S(0.679)DPNLNNHCQEVR;T(0.008)S(0.169)S(0.823)DPNLNNHCQEVR ; 123.54 0.00049928 37834000 7414.7 6645.3 6326.6 7034.5 6684 7243.9 5077.3 5385.2 8606.3 6919.8 TRUE FALSE FALSE 6827.818671 7219.690121 6561.069361 7005.393103 6604.297665 5741.433484 5219.755373 7027.12269 7662.210422 7160.262535 0.953570995 1.008299638 0.916316871 0.978370984 0.922354122 0.801846784 0.728989384 0.981405731 1.070101883 1 12.80579677 -5.457272572 3.508666335 0.974640013 0.827480714 0.472223412 0.070020323 0.136781388 3.286138007 0.008543792 0.019823353 3.49E-06 5.457272572 -0.147159299 LLLAS(ph)PPNER ddPTM_HeLa_Curcumin_4h_R1 1 LLLASPPNER 10 0 Q52LW3 Q52LW3 ARHGAP29 Rho GTPase-activating protein 29 1 0 LLLAS(1)PPNER 105.36 0.0096049 10333000 4314.5 3926.6 3920.3 4125.2 4009.1 4194.4 3060 1451.8 4963 4201.7 TRUE FALSE FALSE 3973.002772 4265.997807 4065.589767 4108.131015 3961.294101 3324.434159 3145.855364 1894.447137 4418.571317 4347.708762 0.913815297 0.981205973 0.93511088 0.944895631 0.91112223 0.76464049 0.723566259 0.4357346 1.016298827 1 12.08603959 -4.044139316 0.760795357 0.960793274 9.93E-20 0.952847419 0.036640385 0.517717546 0.170920527 0.00622702 0.45562334 9.03E-05 4.044139316 -0.960793274 down TSS(ph)EDNLYLAVLR ddPTM_HeLa_Curcumin_4h_R1 9 TSSEDNLYLAVLR 13 0 Q15149-4 Q15149-4 PLEC Plectin 1 0 T(0.007)S(0.168)S(0.825)EDNLYLAVLR;T(0.004)S(0.007)S(0.988)EDNLYLAVLR;T(0.381)S(0.06)S(0.559)EDNLYLAVLR;T(0.001)S(0.031)S(0.967)EDNLYLAVLR;TS(0.043)S(0.956)EDNLYLAVLR;T(0.348)S(0.061)S(0.591)EDNLYLAVLR;T(0.4)S(0.061)S(0.54)EDNLYLAVLR;T(0.405)S(0.027)S(0.568)EDNLYLAVLR;T(0.002)S(0.224)S(0.774)EDNLYLAVLR ;;;;;;;; 234.83 6.08E-20 2768709800 16525.82 16211.19 15849.81 15874.77 15528.42 16977.62 12508.88 9873.97 17322.46 14723.7 TRUE FALSE FALSE 15217.78391 17612.41303 16437.2179 15809.08441 15343.25373 13456.27023 12859.84551 12884.498 15422.22948 15235.34748 0.998847183 1.156023061 1.078886972 1.037658277 1.007082625 0.883226999 0.844079567 0.845697679 1.012266343 1 13.89513478 -5.207997301 2.958299499 1.021761246 0.847069298 0.753489737 0.047644895 0.124731975 2.154111471 0.008030679 0.022640308 6.19E-06 5.207997301 -0.174691948 TSS(ph)EEEDSRREEPSLLLVLK ddPTM_HeLa_Curcumin_4h_R1 1 TSSEEEDSRREEPSLLLVLK 20 2 A0A087WZV0;O43314-2;O43314;D6RBU4 A0A087WZV0 PPIP5K2 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 1 0 T(0.122)S(0.134)S(0.361)EEEDS(0.144)RREEPS(0.239)LLLVLK 56.766 0.015631 6849400 933.8 754.09 781.95 1026.1 974.13 1171 863.19 726.45 806.82 808.27 TRUE FALSE FALSE 859.8887447 819.2701794 810.9297549 1021.85427 962.514136 928.1214001 887.4087882 947.9412608 718.3138646 836.3573223 1.028135609 0.979569566 0.969597244 1.221791503 1.150840807 1.109718747 1.061040257 1.133416586 0.858860018 1 9.707975636 -6.277496487 24.99240486 1.007579793 1.130667977 0.616491045 0.062313488 360.2738756 560754.4496 0.00659963 0.010099681 5.28E-07 6.277496487 0.123088184 TSS(ph)FTEQLDEGTPNR ddPTM_HeLa_Curcumin_4h_R1 3 TSSFTEQLDEGTPNR 15 0 Q13439-3;Q13439-4;Q13439;Q13439-5;Q86W71;E7EVX2;C9J0Y3;C9JHJ5 Q13439-3 GOLGA4 Golgin subfamily A member 4 1 0 T(0.001)SS(0.988)FT(0.011)EQLDEGTPNR;T(0.028)S(0.027)S(0.674)FT(0.271)EQLDEGTPNR;T(0.001)S(0.017)S(0.86)FT(0.121)EQLDEGTPNR ;; 301.75 3.58E-92 208187000 6549.8 6095.9 6719.7 6174.8 7363.9 7557.9 6253.9 6389.1 6480 5363 TRUE FALSE FALSE 6031.376419 6622.802433 6968.737993 6149.250314 7276.090302 5990.306345 6429.367602 8337.107178 5769.160212 5549.363851 1.086859067 1.193434529 1.255772406 1.108100042 1.311157548 1.079458206 1.158577411 1.502353676 1.039607488 1 12.43810668 -1 0.103013294 0.87725905 2.185150762 0.463170601 0.104427807 71.99541802 0.526143973 0.747687971 13.38711486 0.1 1 1.307891712 TSS(ph)FTEQLDEGTPNRESGDTQSFAQK ddPTM_HeLa_Curcumin_4h_R1 1 TSSFTEQLDEGTPNRESGDTQSFAQK 26 1 Q13439-3;Q13439-4;Q13439;Q86W71 Q13439-3 GOLGA4 Golgin subfamily A member 4 1 0 T(0.175)S(0.175)S(0.533)FT(0.056)EQLDEGT(0.004)PNRES(0.056)GDT(0.001)QSFAQK 62.858 0.0011475 10846000 1809.4 1699.9 1447.5 1586.7 1488.3 2122.6 1407.8 1321.3 2074.3 1610.2 TRUE FALSE FALSE 1666.184081 1846.831781 1501.145623 1580.134656 1470.552995 1682.348833 1447.299079 1724.158287 1846.75448 1666.15433 1.000017856 1.108439805 0.900964332 0.948372325 0.882603111 1.00971969 0.868646471 1.034813076 1.10839341 1 10.70230632 -6.71012502 24.99999992 1.008141763 0.938395405 0.335966042 0.066411087 99.57097782 48509.92795 0.008257933 0.011678474 1.95E-07 6.71012502 -0.069746358 TSS(ph)GLGGSTTDFLEEWK ddPTM_HeLa_Curcumin_4h_R1 2 TSSGLGGSTTDFLEEWK 17 0 Q96IZ0;A0A0B4J260;F8W1M8 Q96IZ0 PAWR PRKC apoptosis WT1 regulator protein 1 0 T(0.03)S(0.02)S(0.95)GLGGSTTDFLEEWK;T(0.004)S(0.001)S(0.996)GLGGSTTDFLEEWK ; 241.64 1.94E-30 6820700 2625.4 1816.22 2420.22 2672.4 2416.43 3320.9 2735.8 1460.66 2550.2 2313.8 TRUE FALSE FALSE 2417.59682 1973.205964 2509.915482 2661.342317 2387.61565 2632.107906 2812.559185 1906.00851 2270.44944 2394.204378 1.009770445 0.824159367 1.048329669 1.111576915 0.997248051 1.099366424 1.174736464 0.796092651 0.948310621 1 11.2253306 TSS(ph)IADEGTYTLDSILR ddPTM_HeLa_Curcumin_4h_R1 2 TSSIADEGTYTLDSILR 17 0 E7ERV5;A0A087WY00;G3V394;F8WE88;F8W6H6;Q9Y4I1-2;Q9Y4I1;Q9Y4I1-3 E7ERV5 MYO5A Unconventional myosin-Va 1 0 T(0.044)S(0.076)S(0.88)IADEGTYTLDSILR;TS(0.01)S(0.99)IADEGTYTLDSILR ; 231.17 3.08E-22 42680000 3191.4 2989.6 3423.3 2919.4 3023.8 3971.7 2440.4 2078.4 3215.2 3339.1 TRUE FALSE FALSE 2938.797322 3248.007703 3550.170509 2907.320296 2987.74316 3147.92465 2508.871056 2712.094592 2862.500604 3455.133476 0.850559708 0.940052743 1.027506038 0.841449488 0.864725829 0.911086264 0.726128548 0.784946402 0.828477575 1 11.75452573 -1.194493255 0.214036924 0.96295097 6.32E-34 0.30601183 0.073865761 34.48371495 0.439224162 0.058308117 11.2771766 0.063900866 1.194493255 -0.96295097 ASGSLSPPILAPLS(ph)PGAEISPHDLSLESCR ddPTM_HeLa_Curcumin_4h_R1 1 ASGSLSPPILAPLSPGAEISPHDLSLESCR 30 0 Q9NRF2-3;Q9NRF2-2;Q9NRF2 Q9NRF2-3 SH2B1 SH2B adapter protein 1 1 0 ASGSLS(0.001)PPILAPLS(0.967)PGAEIS(0.029)PHDLS(0.002)LES(0.001)CR 62.108 0.00060251 8695600 607.83 522.9 406.54 508.8 735.79 1075.5 674.88 880 579.2 525.1 TRUE FALSE FALSE 559.7196141 568.097146 421.60673 506.6947204 727.0161848 852.4291766 693.8153165 1148.307949 515.6632091 543.3471859 1.030132535 1.045550912 0.775943524 0.932543194 1.338032484 1.568848056 1.276928149 2.113396331 0.949049194 1 9.08573053 -1.00000001 0.518603624 0.992945958 39.39035619 0.80014863 0.167404947 33.3464109 0.304755443 0.031876353 1415.162273 0.099999998 1.00000001 38.39741023 up TSS(ph)KES(ph)SPIPS(ph)PTSDR ddPTM_HeLa_Curcumin_4h_R1 1 TSSKESSPIPSPTSDR 16 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 3 0 T(0.083)S(0.111)S(0.67)KES(0.568)S(0.568)PIPS(0.754)PT(0.218)S(0.028)DR 119.62 0.0047019 60440000 5703.1 4281.5 5604.4 5637.5 5305.3 6120.2 5720.9 7809.3 6584.3 6458 TRUE FALSE FALSE 5251.693617 4651.573782 5812.103994 5614.173519 5242.037763 4850.801531 5881.413057 10190.31962 5862.018763 6682.415019 0.785897554 0.696091723 0.869761004 0.840141401 0.784452589 0.725905457 0.880132862 1.524945636 0.877230574 1 12.70615387 -4.262695359 5.984301241 0.856884802 1.542774739 0.851910314 0.086410125 0.047684552 8.147968776 0.015680976 0.132800099 5.46E-05 4.262695359 0.685889937 TSS(ph)KES(ph)SPIPSPT(ph)SDR ddPTM_HeLa_Curcumin_4h_R1 1 TSSKESSPIPSPTSDR 16 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 3 0 T(0.335)S(0.08)S(0.589)KES(0.498)S(0.498)PIPS(0.257)PT(0.634)S(0.109)DR 137.69 0.00065939 83637000 2237.2 2085.3 1860.5 1956.8 2159.1 2473.3 1996 3632.6 2296.2 2236.8 TRUE FALSE FALSE 2060.123259 2265.54404 1929.451767 1948.70328 2133.354143 1960.3097 2052.002388 4740.163018 2044.312605 2314.528634 0.890083289 0.978836039 0.833626225 0.841943907 0.921722943 0.8469585 0.886574639 2.048003619 0.883252242 1 11.1765027 -4.260317453 24.99988956 0.922892884 2.048003978 0.972631101 0.05773275 12.52327513 279019.8694 0.009433116 0.077698974 5.49E-05 4.260317453 1.125111094 AES(ph)MLQQADK ddPTM_HeLa_Curcumin_4h_R1 1 AESMLQQADK 10 0 P13797;A0A0A0MSQ0;P13797-3;P13797-2;H7C4N2 P13797 PLS3 Plastin-3 1 0 AES(1)MLQQADK 145.81 0.0011043 9633800 1377.8 755.68 1404.3 1065.7 1703.8 1896.7 1587.8 1939 1217.1 1158.5 TRUE FALSE FALSE 1268.745676 820.997612 1456.344593 1061.290416 1683.483298 1503.30304 1632.349395 2530.192174 1083.587175 1198.757789 1.058383677 0.684873641 1.214878107 0.885325147 1.404356504 1.254050696 1.361700762 2.110678402 0.903925034 1 10.22732447 -1.000000009 0.620742219 1.009991811 78.67333582 0.791731952 0.17142487 52.26191225 0.347182541 0.026763202 5551.944876 0.099999998 1.000000009 77.66334401 up TSS(ph)LDTITGPYLTGQWPR ddPTM_HeLa_Curcumin_4h_R1 3 TSSLDTITGPYLTGQWPR 18 0 Q86VQ1;H7C0Q2;H7C2L5 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 0 T(0.06)S(0.06)S(0.881)LDTITGPYLTGQWPR;T(0.225)S(0.048)S(0.726)LDTITGPYLTGQWPR;T(0.001)S(0.033)S(0.966)LDTITGPYLTGQWPR ;; 302.64 1.28E-96 172486000 3737.9 3201.15 3139.65 3577.52 3476.3 4626 3346.72 3164.56 4057.8 3227.79 TRUE FALSE FALSE 3442.041271 3477.843142 3256.008191 3562.71717 3434.847393 3666.515454 3440.619956 4129.419776 3612.669492 3339.955462 1.030565021 1.041284287 0.974865751 1.066696011 1.028411137 1.097773756 1.030139472 1.236369713 1.081651996 1 11.70561315 -1 0.859580816 1.018611114 78.17506956 0.67120651 0.039304753 228.1418416 0.571896658 0.004938736 34462.09049 0.1 1 77.15645845 TSS(ph)LTQFPPSQSEER ddPTM_HeLa_Curcumin_4h_R1 3 TSSLTQFPPSQSEER 15 0 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4 B7Z7F3 RANBP3 Ran-binding protein 3 1 0 T(0.029)S(0.111)S(0.861)LTQFPPSQSEER;T(0.349)S(0.053)S(0.597)LTQFPPSQSEER;T(0.216)S(0.037)S(0.739)LT(0.008)QFPPSQSEER ;; 238.83 6.10E-29 56031000 8485.9 7208.7 7324.9 7751.92 7758.5 9608.6 10033.5 10975.8 9675.9 7455.8 TRUE FALSE FALSE 7814.232061 7831.787907 7596.367238 7719.844609 7665.984955 7615.668049 10315.01301 14322.27089 8614.477978 7714.888495 1.012876863 1.015152443 0.984637334 1.000642409 0.993661147 0.987139095 1.337026843 1.856445612 1.11660434 1 12.91342959 -4.364283687 2.06955338 1.001902993 1.996710934 0.974028118 0.042376573 0.03041766 0.1668097 0.003200951 0.051937856 4.32E-05 4.364283687 0.994807941 TSS(ph)PHSETQGWK ddPTM_HeLa_Curcumin_4h_R1 1 TSSPHSETQGWK 12 0 H7C1N2;J3KR05;O75128-2;O75128-6;O75128-3;O75128;O75128-7 H7C1N2;O75128-3 COBL Protein cordon-bleu 1 0 TSS(0.999)PHSETQGWK 185.3 4.23E-05 9735000 2251.9 2050.6 2132.8 1707 1907.5 3131.5 2397.4 1356.2 2623.8 2024.7 TRUE FALSE FALSE 2073.659739 2227.844727 2211.843444 1699.936886 1884.754308 2481.991601 2464.664592 1769.699137 2335.975704 2095.058174 0.989786233 1.063380843 1.055743211 0.81140319 0.89961908 1.184688631 1.176418212 0.844701669 1.114993241 1 11.03277459 -5.26878852 24.98692952 0.985329202 1.079384376 0.079446466 0.11885919 848.4020783 2884553.182 0.015446137 0.035207848 5.39E-06 5.26878852 0.094055173 GGCPGGEATLS(ph)QPPPR ddPTM_HeLa_Curcumin_4h_R1 1 GGCPGGEATLSQPPPR 16 0 P20290 P20290 BTF3 Transcription factor BTF3 1 0 GGCPGGEAT(0.001)LS(0.999)QPPPR 176.29 2.32E-05 9795300 1597.8 1628.7 1890.1 1594.4 1740.9 1962.9 1506.3 595.36 1860.1 1950.1 TRUE FALSE FALSE 1471.332444 1769.477571 1960.148769 1587.802795 1720.140905 1555.772414 1548.562724 776.8825233 1656.051684 2017.86583 0.729152762 0.876905463 0.971396978 0.786872334 0.852455539 0.770998939 0.767426011 0.385002071 0.820694646 1 10.97861454 -4.042314387 1.319111042 0.86838853 3.13E-22 0.754595966 0.079514012 1.072562598 1.107107491 0.015716667 1.428093205 9.07E-05 4.042314387 -0.86838853 down TSS(ph)TCS(ph)NESLSVGGTSVTPR ddPTM_HeLa_Curcumin_4h_R1 2 TSSTCSNESLSVGGTSVTPR 20 0 A0A3B3IRT3;O60343-2;O60343-3;O60343;Q5JU47 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 2 0 T(0.182)S(0.137)S(0.597)T(0.407)CS(0.673)NES(0.003)LS(0.001)VGGTSVTPR;T(0.199)S(0.281)S(0.4)T(0.12)CS(0.999)NES(0.001)LSVGGTSVTPR ; 185.85 1.11E-07 129307700 3143.3 2562.3 2629.5 2958.4 2761.4 3002.4 1669.2 1599.13 3615.9 2470.8 TRUE FALSE FALSE 2894.504488 2783.773795 2726.951583 2946.158925 2728.472109 2379.668396 1716.03326 2086.697376 3219.244817 2556.660116 1.132142857 1.088832175 1.066607003 1.15234673 1.067201734 0.930772292 0.671201169 0.816180986 1.25916026 1 11.32004467 -4.994929437 3.263665415 1.072717504 0.744866908 0.766675025 0.079071823 0.071247019 1.573726012 0.009027315 0.029201811 1.01E-05 4.994929437 -0.327850596 TSS(ph)TDEVLSLEEK ddPTM_HeLa_Curcumin_4h_R1 1 TSSTDEVLSLEEK 13 0 K7ENH8;A0A0A0MRB7;P15923-2;K7EMM4 K7ENH8 TCF3 Transcription factor E2-alpha 1 0 T(0.042)S(0.069)S(0.881)T(0.008)DEVLSLEEK 179.83 0.00015608 74320000 4506.1 3826.3 4319.5 4113 4787.9 5760.4 6423.3 5608 4589.8 4651.9 TRUE FALSE FALSE 4149.43743 4157.028322 4479.58447 4095.981496 4730.80742 4565.628107 6603.520511 7317.853384 4086.310423 4813.553179 0.862032116 0.863609099 0.930619088 0.850926819 0.982809838 0.948494374 1.371859885 1.520260214 0.848917685 1 12.23288651 -4.695958259 3.086610381 0.924144972 1.500239794 0.940701153 0.054242648 0.046813031 0.865145218 0.008876909 0.041103707 2.01E-05 4.695958259 0.576094822 TSS(ph)TDEVLSLEEKDLR ddPTM_HeLa_Curcumin_4h_R1 1 TSSTDEVLSLEEKDLR 16 1 K7ENH8;A0A0A0MRB7;P15923-2;K7EMM4 K7ENH8 TCF3 Transcription factor E2-alpha 1 0 T(0.031)S(0.097)S(0.436)T(0.436)DEVLSLEEKDLR 135.95 0.0001855 18520000 3925.4 3032.1 3268.9 3682.5 3456.8 5328.7 4584.7 5367 5701 5350.2 TRUE FALSE FALSE 3614.700448 3294.181213 3390.04831 3667.262791 3415.579918 4223.467553 4713.334343 7003.373593 5075.614563 5536.119052 0.652930404 0.595034388 0.612351049 0.662424842 0.616962873 0.762893195 0.851378791 1.265033054 0.916818175 1 12.43465925 -4.258497822 2.880923095 0.768030423 1.354365568 0.582208624 0.133219078 0.321589966 3.705235374 0.024839677 0.439428583 5.51E-05 4.258497822 0.586335146 TSS(ph)TNEDEDLNPEQK ddPTM_HeLa_Curcumin_4h_R1 2 TSSTNEDEDLNPEQK 15 0 Q99081;Q99081-3;B4DGI9;F5GY10;Q99081-4;Q99081-2;B4DZP2 Q99081 TCF12 Transcription factor 12 1 0 TS(0.001)S(0.925)T(0.074)NEDEDLNPEQK;T(0.01)S(0.005)S(0.916)T(0.069)NEDEDLNPEQK ; 300.56 4.05E-92 75307000 6471.5 5444.2 6653 6782.5 8043.8 7903.6 6367.3 4968.2 5744.5 5318.9 TRUE FALSE FALSE 5959.273946 5914.772389 6899.566033 6754.435812 7947.882939 6264.304268 6545.949301 6482.981309 5114.342722 5503.731379 1.082769768 1.074684061 1.253616057 1.227246634 1.444089908 1.138192226 1.189365696 1.177924732 0.929250061 1 12.42619434 -6.833341343 3.851880428 1.040667775 1.24111495 0.598691047 0.08664104 0.122809308 3.607424432 0.013448722 0.018153225 1.47E-07 6.833341343 0.200447175 TSS(ph)TNEDEDLNPEQKIER ddPTM_HeLa_Curcumin_4h_R1 2 TSSTNEDEDLNPEQKIER 18 1 Q99081;Q99081-3;B4DGI9;F5GY10;Q99081-4;Q99081-2;B4DZP2 Q99081 TCF12 Transcription factor 12 1 0 T(0.145)S(0.145)S(0.685)T(0.025)NEDEDLNPEQKIER;T(0.127)S(0.127)S(0.593)T(0.153)NEDEDLNPEQKIER ; 136.92 0.00012741 16530400 3505.5 2576.4 2686.6 3073.2 2056.15 3143.9 2635 1920.96 4817.3 4205 TRUE FALSE FALSE 3228.035976 2799.092536 2786.167759 3060.483913 2031.631754 2491.819701 2708.931008 2506.651861 4288.854242 4351.123437 0.741885635 0.643303408 0.640332962 0.703377865 0.466921195 0.572684213 0.622581972 0.576093025 0.985688939 1 12.08717223 -8.299623127 0.376985467 1.051579212 0.554834518 0.894070527 0.053659614 0.310444256 0.10011884 0.063572376 0.027011669 5.02E-09 8.299623127 -0.496744694 TSS(ph)VPEYVYNLHLVENDFVGGR ddPTM_HeLa_Curcumin_4h_R1 1 TSSVPEYVYNLHLVENDFVGGR 22 0 Q99959-2;Q99959 Q99959-2 PKP2 Plakophilin-2 1 0 T(0.057)S(0.057)S(0.883)VPEY(0.004)VYNLHLVENDFVGGR 113.62 6.45E-06 3109800 685.76 521.49 817.44 712.68 620.6 975.7 496.43 392.86 717.6 678.99 TRUE FALSE FALSE 631.4813724 566.5652719 847.7350455 709.731119 613.1997503 773.3288216 510.3584897 512.6412055 638.8810753 702.584852 0.898797306 0.806401206 1.206594539 1.010171394 0.872776788 1.100690998 0.726401214 0.729650239 0.909329419 1 9.456528662 -4.739255442 24.94346248 0.965432142 0.728025411 0.445317052 0.110054381 161.8244981 181951.3308 0.014732366 0.055033225 1.82E-05 4.739255442 -0.237406731 TSS(ph)VSNPQDSVGSPCSR ddPTM_HeLa_Curcumin_4h_R1 1 TSSVSNPQDSVGSPCSR 17 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-3;A0A1B0GU60;F5H836 A0A1B0GTU4 PXN Paxillin 1 0 TSS(0.977)VS(0.023)NPQDSVGSPCSR 232.26 2.55E-22 11835000 1146.3 1344.5 1257.8 1241 1207.6 2002.7 1440.6 903.74 1472.1 1280.1 TRUE FALSE FALSE 1055.569145 1460.712589 1304.415174 1235.865071 1193.200159 1587.317445 1481.019359 1179.286166 1310.614313 1324.58338 0.79690653 1.10277134 0.984773925 0.933021726 0.900811664 1.198352229 1.118102025 0.890307235 0.989453992 1 10.37132295 -5.289858337 24.93628608 0.925558081 1.07383868 0.138615173 0.106255036 707.6183379 620900.2228 0.016827072 0.037633378 5.13E-06 5.289858337 0.148280599 TSS(ph)VVTLEVAK ddPTM_HeLa_Curcumin_4h_R1 1 TSSVVTLEVAK 11 0 A8MQ02;J3KN01;P55196-3;P55196;P55196-5;Q5TIG5;P55196-2;P55196-6;P55196-1 A8MQ02 MLLT4 Afadin 1 0 T(0.059)S(0.032)S(0.903)VVT(0.006)LEVAK 178.95 0.00016872 10492000 3976.1 3281 3490.5 3757.4 3872.3 4392.3 4143.2 3497.5 3699.3 3991.6 TRUE FALSE FALSE 3661.387489 3564.59502 3619.861001 3741.852874 3826.125352 3481.287469 4259.447041 4563.871649 3293.496045 4130.307803 0.886468434 0.863033747 0.876414343 0.905950126 0.926353564 0.84286393 1.03126625 1.104971316 0.797397241 1 12.01203358 -4.565398332 6.023658943 0.924580545 1.088304633 0.542095372 0.060661626 0.097568793 8.763705682 0.008336494 0.033195285 2.72E-05 4.565398332 0.163724088 TSSAFVGK(ac)TPEASPEPK ddPTM_HeLa_Curcumin_4h_R1 2 TSSAFVGKTPEASPEPK 17 1 A0A087WW66;Q99460-2;Q99460 A0A087WW66 PSMD1 26S proteasome non-ATPase regulatory subunit 1 0 1 ; TSSAFVGK(1)TPEASPEPK;TSSAFVGK(1)TPEASPEPK 296.25 1.85E-112 5432300 2618.3 2500.5 2670.9 2644.6 2697.4 2867.5 2365.2 1929.21 2771 2486.4 FALSE TRUE FALSE 2411.058792 2716.632078 2769.885904 2633.657346 2665.235267 2272.748177 2431.561146 2517.417248 2467.028233 2572.802215 0.937133363 1.055903972 1.076602736 1.023653249 1.035926995 0.883374619 0.945102244 0.978472901 0.958887636 1 11.32912484 -5.267504272 24.96349979 0.992323487 0.936595154 0.29428952 0.047864047 650.4564184 2677325.266 0.008079907 0.018510345 5.40E-06 5.267504272 -0.055728333 TSSAFVGKT(ph)PEASPEPK ddPTM_HeLa_Curcumin_4h_R1 1 TSSAFVGKTPEASPEPK 17 1 A0A087WW66;Q99460-2;Q99460 A0A087WW66 PSMD1 26S proteasome non-ATPase regulatory subunit 1 1 0 T(0.007)S(0.002)S(0.002)AFVGKT(0.822)PEAS(0.166)PEPK 65.598 0.02035 32250000 2478.6 1776.3 2001.4 2193.4 2029 2613.3 1951.8 2881.3 2227.7 2011.3 TRUE FALSE FALSE 2282.416195 1929.835457 2075.573645 2184.324292 2004.8055 2071.272122 2006.562255 3759.795106 1983.326883 2081.192525 1.096686715 0.927273875 0.997300163 1.049554169 0.963296512 0.995233308 0.964140622 1.806558048 0.952976171 1 11.02319472 -4.258837799 24.99990655 1.022723576 1.806558326 0.952829181 0.053895974 38.65276478 371412.2425 0.008044264 0.073401692 5.51E-05 4.258837799 0.78383475 TSSEDNLYLAVLR ddPTM_HeLa_Curcumin_4h_R1 1 TSSEDNLYLAVLR 13 0 Q15149-4 Q15149-4 PLEC Plectin 0 0 202.05 6.89E-08 3216200 975.89 911.09 783.21 605.26 1035.9 988.72 594.25 610.78 948.21 657.91 FALSE FALSE TRUE 898.6472767 989.8405599 812.2364516 602.7555945 1023.547569 783.6483268 610.9230557 797.0040103 844.1937353 680.7723235 1.32004085 1.453996477 1.193110271 0.885399676 1.503509373 1.151116606 0.897397022 1.170735035 1.240052961 1 9.411028576 -4.97791093 24.08473147 1.186220652 1.031613515 0.117355722 0.188618533 301.2731558 328485.4349 0.028422133 0.085255427 1.05E-05 4.97791093 -0.154607137 TSSESIYSRPGSSIPGS(ph)PGHTIYAK ddPTM_HeLa_Curcumin_4h_R1 1 TSSESIYSRPGSSIPGSPGHTIYAK 25 1 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;A0A494C1P1;A0A494C1G0;H0Y7N6;F6XFR5 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 T(0.003)S(0.003)S(0.003)ES(0.003)IY(0.003)S(0.003)RPGS(0.003)S(0.007)IPGS(0.913)PGHT(0.059)IY(0.001)AK 50.255 0.009465 23835000 853.45 736.99 786.46 716.04 885.54 1055.6 759.6 606.66 787.78 1211.7 TRUE FALSE FALSE 785.8985319 800.6921316 815.6068994 713.0772162 874.9805139 836.6566609 780.9123316 791.6278413 701.3625049 1253.806485 0.626810071 0.638609021 0.650504611 0.568729884 0.697859298 0.667293295 0.622833221 0.631379604 0.559386567 1 10.29209898 -9.186140038 0.69169517 1.030713174 0.634237447 0 0.13976728 0.148396994 0.11347843 0.034558293 0.007399894 6.51E-10 9.186140038 -0.396475728 TSSGDPPS(ph)PLVK ddPTM_HeLa_Curcumin_4h_R1 2 TSSGDPPSPLVK 12 0 Q99618;F5GX58;F8WDL1 Q99618 CDCA3 Cell division cycle-associated protein 3 1 0 TSSGDPPS(1)PLVK;TSS(0.001)GDPPS(0.999)PLVK ; 164.22 0.00011807 115325000 16615.8 14140.3 14701 16279.7 15733.7 23778 22127 16839.6 17560.8 13860.5 TRUE FALSE FALSE 15300.6419 15362.52452 15245.83199 16212.33891 15546.0859 18846.17477 22747.82407 21973.91652 15634.42417 14342.15134 1.066830319 1.071145057 1.063008724 1.130397981 1.083943791 1.314040991 1.58608172 1.532121367 1.090103137 1 13.80797383 -5.044326275 1.830233582 1.044219909 1.578829806 0.954889277 0.042237657 0.051154775 0.322569022 0.00665655 0.02755287 9.03E-06 5.044326275 0.534609897 TSSIQSRPLPS(ph)PPK ddPTM_HeLa_Curcumin_4h_R1 1 TSSIQSRPLPSPPK 14 1 P56945-6;A0A2R8Y6M6;A0A2R8Y5C9;A0A2R8Y8C4;A0A2R8YFS8;A0A2R8Y5E4;A0A2R8Y4C2;A0A2R8YFK2;A0A2R8Y596;P56945;P56945-8;P56945-2;P56945-3;P56945-5;P56945-7;P56945-4 P56945-6 BCAR1 Breast cancer anti-estrogen resistance protein 1 1 0 TSSIQSRPLPS(1)PPK 68.261 0.015581 38346000 3430 2881.4 2922.6 3082.8 3461.6 3547.8 2539.9 2645.7 3419.2 2821.9 TRUE FALSE FALSE 3158.511881 3130.455377 3030.914127 3070.04419 3420.322681 2811.946288 2611.162758 3452.361751 3044.122314 2919.960815 1.081696667 1.072088146 1.03799822 1.051399106 1.171359103 0.963008227 0.894245822 1.182331534 1.042521632 1 11.51173329 -3.924080303 15.95481551 1.038923317 3.515353332 0.284385015 0.069891241 2240230.446 7758686.18 0.009779251 188842217.8 0.000119102 3.924080303 2.476430015 AAHTEDINACTLTTS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 AAHTEDINACTLTTSPR 17 0 H7C155;P04049;P04049-2 H7C155 RAF1 RAF proto-oncogene serine/threonine-protein kinase 1 0 AAHTEDINACTLTT(0.004)S(0.996)PR 195.45 3.60E-26 0 857.88 768.29 812.83 897.21 830.3 1262.1 1093.3 1264 1090.7 793.96 TRUE FALSE FALSE 789.9778928 834.6975642 842.9541948 893.4975827 820.3992148 1000.326233 1123.975056 1649.387781 971.0529388 821.5500509 0.961570013 1.016003302 1.026053366 1.087575348 0.998599189 1.217608388 1.368115131 2.007653434 1.181976604 1 9.68220466 -1.000000005 0.715260346 0.987131395 145.4255296 0.940671325 0.072809959 22.89388173 0.106765134 0.006308628 5308.447641 0.099999999 1.000000005 144.4383982 up TSSKESS(ph)PIPS(ph)PTSDR ddPTM_HeLa_Curcumin_4h_R1 2 TSSKESSPIPSPTSDR 16 1 A0A087WUZ3;Q01082 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 2 0 T(0.034)S(0.045)S(0.01)KES(0.383)S(0.528)PIPS(0.994)PT(0.005)S(0.001)DR;T(0.001)S(0.001)S(0.002)KES(0.416)S(0.58)PIPS(0.779)PT(0.212)S(0.01)DR ; 141.86 0.0015483 28135000 6253.7 4402.4 4322.1 5212.5 3633.1 5651 3884.2 4172.3 7990.2 6091.7 TRUE FALSE FALSE 5758.713046 4782.923839 4482.280828 5190.932056 3589.777655 4478.9189 3993.180198 5444.415063 7113.69505 6303.386122 0.9135904 0.758786428 0.71109095 0.823514847 0.569499882 0.710557598 0.633497635 0.863728631 1.128551371 1 12.62191132 -7.312122665 1.075762517 0.97600369 0.70326297 0.662765687 0.094113529 0.180426523 0.4098888 0.016437339 0.019063648 4.87E-08 7.312122665 -0.272740721 TSSLDT(ph)LAAPYLAGHWPR ddPTM_HeLa_Curcumin_4h_R1 1 TSSLDTLAAPYLAGHWPR 18 0 Q6P1L5;Q6P1L5-2 Q6P1L5 FAM117B Protein FAM117B 1 0 T(0.097)S(0.097)S(0.097)LDT(0.709)LAAPYLAGHWPR 114.56 0.00063143 0 618.82 802.35 586.17 747.72 641.63 740.66 552.35 542.55 708.65 781.3 TRUE FALSE FALSE 569.839744 871.7015588 607.8939758 744.6261328 633.9789813 587.038767 567.8474544 707.9709974 630.912868 808.4501168 0.704854551 1.078237903 0.751925151 0.9210539 0.784190599 0.726128619 0.702390219 0.875713891 0.780398017 1 9.659014949 -9.555618043 1.278207734 1.001748766 0.805428993 0 0.129436574 0.469465765 1.354183021 0.081332033 0.018485305 2.78E-10 9.555618043 -0.196319773 TSSPRS(ph)PPSSSEIFTPAHEENVR ddPTM_HeLa_Curcumin_4h_R1 1 TSSPRSPPSSSEIFTPAHEENVR 23 1 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 0 T(0.079)S(0.079)S(0.238)PRS(0.551)PPS(0.036)S(0.017)SEIFTPAHEENVR 48.224 0.014709 15588000 536.7 549 480.31 463.52 422.66 652.61 523.25 517.74 835.65 606.75 TRUE FALSE FALSE 494.2196287 596.4531137 498.1107111 461.6020771 417.6200555 517.2513296 537.9309867 675.5965426 743.9812857 627.8345173 0.787181359 0.950016441 0.793378983 0.735228893 0.665175367 0.823865709 0.856803779 1.076074227 1.184995831 1 9.294240538 -9.387539848 0.871308434 1.011533646 0.825763054 0.358784921 0.123316104 0.797864871 0.970595545 0.103477229 0.020765034 4.10E-10 9.387539848 -0.185770593 TSSPRSPPS(ph)SSEIFTPAHEENVR ddPTM_HeLa_Curcumin_4h_R1 1 TSSPRSPPSSSEIFTPAHEENVR 23 1 I3L3A7;I3L2L5;I3L317;I3L4Q0;C9JLW8 I3L3A7 FAM195B Protein FAM195B 1 0 T(0.032)S(0.032)S(0.013)PRS(0.223)PPS(0.233)S(0.233)S(0.233)EIFT(0.001)PAHEENVR 48.788 0.013835 24963000 753.73 511.3 625.22 633.79 684.77 744.19 666.91 422.44 718.41 709.69 TRUE FALSE FALSE 694.0714752 555.4944937 648.3912032 631.1675449 676.604565 589.8366053 685.6216997 551.2400113 639.6022204 734.3516747 0.945148624 0.75644206 0.882943725 0.859489488 0.92136314 0.803207272 0.933642182 0.750648538 0.870975368 1 9.520327313 -7.461264552 6.469072392 0.976205589 0.850544477 0.249700988 0.067685099 0.134046112 10.95470788 0.009536378 0.010761686 3.46E-08 7.461264552 -0.125661111 TSSSS(ph)PANSDVEIDGIGR ddPTM_HeLa_Curcumin_4h_R1 1 TSSSSPANSDVEIDGIGR 18 0 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 0 T(0.178)S(0.015)S(0.228)S(0.228)S(0.336)PANS(0.015)DVEIDGIGR 81.606 0.0058403 2233500 724.34 632.4 666.03 780.22 1011.8 943.75 874.71 579.1 938 560.49 TRUE FALSE FALSE 667.0077247 687.0618381 690.7136577 776.9916564 999.7349458 748.0056117 899.2520084 755.6649242 835.1037468 579.9669858 1.150078782 1.184656808 1.190953407 1.339717045 1.72377906 1.289738261 1.550522755 1.302944724 1.439916008 1 9.179826968 -6.555323341 1.089818702 1.065241809 1.464215288 0.245390785 0.17337145 0.212263248 0.503888923 0.022908884 0.039484261 2.78E-07 6.555323341 0.398973479 TSSSSPANS(ph)DVEIDGIGR ddPTM_HeLa_Curcumin_4h_R1 4 TSSSSPANSDVEIDGIGR 18 0 O60293-2;O60293 O60293-2 ZFC3H1 Zinc finger C3H1 domain-containing protein 1 0 TSSSSPANS(1)DVEIDGIGR;TSSSSPANS(1)DVEIDGIGR;TSSSS(0.001)PANS(0.999)DVEIDGIGR;TSSSSPANS(1)DVEIDGIGR ;;; 159.5 1.43E-06 5823200 3960.37 4229.67 4401.39 4310.94 4422.94 4625.78 3125.34 2787.99 4903.85 4253.41 TRUE FALSE FALSE 3646.902536 4595.263828 4564.509385 4293.102473 4370.199329 3666.341085 3213.028629 3638.035317 4365.909924 4401.215681 0.828612547 1.04408967 1.037101955 0.975435603 0.992952776 0.833029179 0.730032078 0.826597827 0.991978181 1 12.10368636 -5.077546649 4.666824045 0.944332106 0.778257451 0.584227466 0.067460392 0.160256801 6.338292287 0.012179257 0.033118134 8.36E-06 5.077546649 -0.166074655 TSSSTS(ph)PLEPPSDR ddPTM_HeLa_Curcumin_4h_R1 2 TSSSTSPLEPPSDR 14 0 A0A2R8Y549;Q8NI35-4;Q8NI35-3;Q8NI35-2;Q8NI35;A0A0U1RR46;A0A0X1KG69;A0A087WUZ6 A0A2R8Y549 INADL InaD-like protein 1 0 TS(0.001)S(0.003)S(0.017)T(0.091)S(0.887)PLEPPSDR;T(0.001)SS(0.006)S(0.036)T(0.202)S(0.755)PLEPPSDR ; 135.91 0.00089855 18181500 3196 2821.5 2717.9 2519.45 2966.9 3509.3 2599.4 3099.7 3123.9 2909.4 TRUE FALSE FALSE 2943.033228 3065.377888 2818.627765 2509.025183 2931.521655 2781.431622 2672.332168 4044.784261 2781.215986 3010.501433 0.977589047 1.018228343 0.936265213 0.833424344 0.973765241 0.923909748 0.88767012 1.343558324 0.92383812 1 11.55578809 -4.253977399 24.77782001 0.966699746 1.343558527 0.811139184 0.057039453 275.9457392 916264.3896 0.008265572 0.115026243 5.57E-05 4.253977399 0.376858782 TSST(ph)CS(ph)NESLSVGGTSVTPR ddPTM_HeLa_Curcumin_4h_R1 2 TSSTCSNESLSVGGTSVTPR 20 0 A0A3B3IRT3;O60343-2;O60343-3;O60343;Q5JU47 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 2 0 T(0.124)S(0.125)S(0.248)T(0.732)CS(0.762)NES(0.007)LS(0.003)VGGTSVTPR;T(0.11)S(0.137)S(0.332)T(0.428)CS(0.944)NES(0.032)LS(0.018)VGGTSVTPR ; 89.624 0.0056459 122793600 6272.7 5175.5 5427.4 5492.9 5812.5 5721.5 3720.1 2751.5 7398.1 5565.7 TRUE FALSE FALSE 5776.209176 5622.847158 5628.544218 5470.171835 5743.189734 4534.796405 3824.475994 3590.419684 6586.546939 5759.107661 1.002969473 0.976339997 0.977329224 0.949829758 0.997236043 0.787413029 0.664074405 0.623433333 1.143674911 1 12.49162958 -5.025038288 1.910439917 0.995245412 0.626877723 0.894066124 0.051158158 0.033012871 0.228480672 0.003060818 0.012570426 9.44E-06 5.025038288 -0.36836769 TSST(ph)CSNESLSVGGTSVT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 TSSTCSNESLSVGGTSVTPR 20 0 A0A3B3IRT3;O60343-2;O60343-3;O60343;Q5JU47 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 2 0 T(0.045)S(0.062)S(0.088)T(0.793)CS(0.013)NESLSVGGT(0.003)S(0.099)VT(0.898)PR 188.73 4.44E-30 0 1797.3 1374.5 1430 1801.8 1483.8 2060.2 1730.9 988.46 1810.4 1590.2 TRUE FALSE FALSE 1655.041808 1493.305655 1482.997058 1794.344629 1466.106654 1632.891297 1779.464396 1289.836904 1611.803649 1645.459332 1.005823588 0.907531184 0.901266309 1.090482514 0.891001452 0.99236199 1.081439305 0.783876501 0.97954633 1 10.68427465 -4.24487631 24.39933157 0.991328604 0.783876276 0.44683151 0.06601166 1530.886614 2255124.976 0.008515528 0.301992573 5.69E-05 4.24487631 -0.207452328 TSST(ph)NEDEDLNPEQK ddPTM_HeLa_Curcumin_4h_R1 1 TSSTNEDEDLNPEQK 15 0 Q99081;Q99081-3;B4DGI9;F5GY10;Q99081-4;Q99081-2;B4DZP2 Q99081 TCF12 Transcription factor 12 1 0 T(0.052)S(0.052)S(0.115)T(0.781)NEDEDLNPEQK 154.31 0.00037242 8287200 1959 1759.8 1697.1 1640.3 1939.4 1965.2 2096 1507.3 1654.1 1454.8 TRUE FALSE FALSE 1803.943083 1911.90927 1759.996019 1633.512873 1916.273922 1557.595368 2154.808119 1966.868831 1472.649368 1505.354192 1.198351254 1.270072705 1.169157417 1.085135234 1.272972123 1.034703578 1.431429315 1.306582093 0.978274333 1 10.55588726 -13.52287875 0.126582882 0.234611218 1.329754304 0.465157887 0.103262583 61.05408948 0.551589218 11.84901379 0.409905232 3.00E-14 13.52287875 1.095143087 TSSTCS(ph)NESLSVGGTSVTPR ddPTM_HeLa_Curcumin_4h_R1 1 TSSTCSNESLSVGGTSVTPR 20 0 A0A3B3IRT3;O60343-2;O60343-3;O60343;Q5JU47 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 1 0 TSS(0.001)T(0.02)CS(0.965)NES(0.013)LSVGGTSVTPR 169.62 2.69E-06 35375000 1340.8 827.33 942.5 969.18 1381.4 1279.9 1274.7 1087.2 1396.5 1008.5 TRUE FALSE FALSE 1234.674265 898.8407187 977.4298791 965.16979 1364.927707 1014.434313 1310.464651 1418.682275 1243.307444 1043.5453 1.183153492 0.861333685 0.936643459 0.924894961 1.307971688 0.972103763 1.255781279 1.359483173 1.191426423 1 10.02727751 -4.602571737 4.733887741 1.059839151 1.337738207 0.383427543 0.133899417 0.153571381 6.073675277 0.018734303 0.077594394 2.50E-05 4.602571737 0.277899056 TSSTCSNESLSVGGTSVT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 TSSTCSNESLSVGGTSVTPR 20 0 A0A3B3IRT3;O60343-2;O60343-3;O60343;Q5JU47 A0A3B3IRT3 TBC1D4 TBC1 domain family member 4 1 0 TSSTCSNESLSVGGT(0.061)S(0.21)VT(0.729)PR 139.74 0.00036176 4784100 791.11 634.97 578.83 723.65 690.25 1002.9 930.17 711.81 1004.4 547.12 TRUE FALSE FALSE 728.4928087 689.8539774 600.281949 720.655728 682.0192196 794.887235 956.2680668 928.8375922 894.2198329 566.1323793 1.286788807 1.218538283 1.060320821 1.272945612 1.204699191 1.404066017 1.689124491 1.640672087 1.57952427 1 9.144995629 -1 0.293235195 1.093198503 6.406497512 0.36089471 0.180147108 18.45412086 0.235974782 0.047718661 51.74017841 0.1 1 5.313299009 TSSVSNPQDSVGS(ph)PCSR ddPTM_HeLa_Curcumin_4h_R1 3 TSSVSNPQDSVGSPCSR 17 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-3;A0A1B0GU60;F5H836 A0A1B0GTU4 PXN Paxillin 1 0 TSSVSNPQDSVGS(1)PCSR;TSSVSNPQDS(0.004)VGS(0.995)PCS(0.002)R;TSSVSNPQDS(0.001)VGS(0.966)PCS(0.034)R ;; 321.93 6.25E-113 425921200 7167.3 6274.4 6240 6579.7 6023.8 8684.4 8103.8 7178.4 8014.8 5698.5 TRUE FALSE FALSE 6600.000642 6816.731178 6471.259889 6552.474945 5951.970119 6883.157547 8331.170818 9367.061115 7135.596492 5896.522451 1.119303911 1.156059565 1.097470576 1.111243958 1.009403452 1.167324911 1.412895633 1.588573806 1.210136407 1 12.52564864 -4.668835581 2.033607702 1.069411047 1.591864638 0.858593039 0.065025367 0.084161212 0.61102717 0.008747535 0.059924118 2.14E-05 4.668835581 0.522453591 TSSVSSISQVS(ph)PER ddPTM_HeLa_Curcumin_4h_R1 4 TSSVSSISQVSPER 14 0 P42356 P42356 PI4KA Phosphatidylinositol 4-kinase alpha 1 0 TSSVSSISQVS(1)PER;TSSVSSISQVS(1)PER;TSSVSSISQVS(1)PER;TSSVSSISQVS(0.999)PER ;;; 184 7.35E-05 77829000 6526.8 5412.23 5435.49 6044.48 5082.41 6661.2 3831.79 3425.16 7398.1 6102.76 TRUE FALSE FALSE 6010.196893 5880.039045 5636.934041 6019.469543 5021.80558 5279.592033 3939.299715 4469.475517 6586.546939 6314.830456 0.951759027 0.931147572 0.8926501 0.95322742 0.79523997 0.836062357 0.623817178 0.707774428 1.04302831 1 12.62452828 -4.809614508 0.464275189 0.984647335 0.51500353 0.833288959 0.051362732 0.716579427 0.143579851 0.010426383 0.167905828 1.55E-05 4.809614508 -0.469643805 TST(ph)PEDFIR ddPTM_HeLa_Curcumin_4h_R1 2 TSTPEDFIR 9 0 Q9Y490 Q9Y490 TLN1 Talin-1 1 0 T(0.15)S(0.173)T(0.677)PEDFIR;T(0.184)S(0.184)T(0.632)PEDFIR ; 156.16 0.003346 7788900 5825.9 5250.1 5826.5 5378.9 5841.7 5877.7 5568.6 5163.6 5289.1 4779.7 TRUE FALSE FALSE 5364.773868 5703.89525 6042.435216 5356.643537 5772.041543 4658.598765 5724.839929 6737.95787 4708.898963 4945.794219 1.084714331 1.15328196 1.221732031 1.083070443 1.167060595 0.941931378 1.157516806 1.362361144 0.952101675 1 12.2719865 -1.7173873 0.020009342 5.74E-07 2.508740385 0.353268332 0.098540887 2315.978567 4.067685605 196.2090965 329.9870812 0.019169585 1.7173873 2.508739811 TST(ph)SPPPEK ddPTM_HeLa_Curcumin_4h_R1 1 TSTSPPPEK 9 0 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 T(0.041)S(0.006)T(0.885)S(0.068)PPPEK 123.86 0.015175 63346000 9822 9402.9 9725.7 8994.5 10702 10080 8525.5 8513.1 7837.7 7686 TRUE FALSE FALSE 9044.578336 10215.64478 10086.143 8957.283142 10574.38564 7989.294375 8764.702585 11108.705 6977.923919 7953.087928 1.137241084 1.284487845 1.268204638 1.12626482 1.329594962 1.004552502 1.102050256 1.396778849 0.877385486 1 12.95729941 -8.290975623 0.874913808 1.017788918 1.204322864 0.41385037 0.120114937 0.440843721 0.712964844 0.038322634 0.023916465 5.12E-09 8.290975623 0.186533946 TSTGAPAAIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 TSTGAPAAIKK 11 1 P40121-2;P40121;B8ZZL6;E7ENU9 P40121-2 CAPG Macrophage-capping protein 0 1 ; TSTGAPAAIK(1)K;TSTGAPAAIK(1)K 166.34 3.72E-09 16244100 13734.2 10995.7 8703 7280.4 9075.9 16041.7 9910.4 6806.2 13128.8 11017.1 FALSE TRUE FALSE 12647.12358 11946.11931 9025.540836 7250.275634 8967.67582 12714.47059 10188.45915 8881.379048 11688.60349 11399.9434 1.109402313 1.047910405 0.791718039 0.635992248 0.786642135 1.115309975 0.893728924 0.779072205 1.025321186 1 13.47673904 -6.770079162 24.5133683 1.052824349 0.838139266 0.4416616 0.116552603 111.2878934 315753.171 0.020441594 0.027106853 1.70E-07 6.770079162 -0.214685083 TSTS(ph)SSSVQAR ddPTM_HeLa_Curcumin_4h_R1 1 TSTSSSSVQAR 11 0 S4R3H4;E7EQT4;Q9UKV3;Q9UKV3-5 S4R3H4;Q9UKV3-5 ACIN1 Apoptotic chromatin condensation inducer in the nucleus 1 0 T(0.107)S(0.107)T(0.065)S(0.612)S(0.055)S(0.055)SVQAR 135.1 0.0020816 2815600 2022.9 1580.1 1747.4 1811.4 1544 1964.3 1691.6 1648.8 2051.6 1964.8 TRUE FALSE FALSE 1862.78533 1716.676803 1812.160181 1803.904907 1525.588808 1556.882038 1739.061743 2151.51153 1826.544613 2033.076654 0.916239595 0.844373871 0.891338838 0.887278354 0.750384303 0.765776359 0.855384247 1.058254014 0.898414041 1 10.9894489 -8.016964954 0.695934509 0.990509589 0.854309962 0.09322035 0.084785523 0.553637632 0.596859951 0.030969613 0.021272957 9.62E-09 8.016964954 -0.136199627 TSTTAEK(ac)TDEEEKEDR ddPTM_HeLa_Curcumin_4h_R1 2 TSTTAEKTDEEEKEDR 16 2 I3L0H8;Q9NUU7;H3BTB3 I3L0H8 DDX19A ATP-dependent RNA helicase DDX19A 0 1 ; TSTTAEK(1)TDEEEKEDR;TSTTAEK(1)TDEEEKEDR 162.81 0.00022701 2869000 1034.12 1215.86 669.92 1079.07 1175.43 1633.75 1370.17 1271.02 1740.92 931.03 FALSE TRUE FALSE 952.2683108 1320.953521 694.7478245 1074.605094 1161.413765 1294.891834 1408.613283 1658.548147 1549.945432 963.3832232 0.988462626 1.371161018 0.721154166 1.11544925 1.205557391 1.344108764 1.462152598 1.721587118 1.608856574 1 9.91196599 -4.530059027 0.693453596 1.002804163 1.997537851 0.297185455 0.244448927 0.83129515 0.344400696 0.024485395 0.600421361 2.95E-05 4.530059027 0.994733688 TSTTAEKTDEEEKEDR ddPTM_HeLa_Curcumin_4h_R1 1 TSTTAEKTDEEEKEDR 16 2 I3L0H8;Q9NUU7;H3BTB3 I3L0H8 DDX19A ATP-dependent RNA helicase DDX19A 0 0 64.374 0.012947 8124800 3578 2660.5 2740.1 3394.7 3143.8 3694.4 3125.8 2875.3 3733.9 3255.4 FALSE FALSE TRUE 3294.797525 2890.461765 2841.650516 3380.653631 3106.312238 2928.139796 3213.501535 3751.965734 3324.300512 3368.524908 0.978112858 0.85807938 0.843588988 1.003600604 0.922158014 0.869264701 0.953978855 1.113830486 0.986871287 1 11.71790125 -7.493258282 19.14189249 0.990344544 0.932938766 0.086988018 0.074847049 39.05910349 25243.73485 0.01294584 0.014165652 3.21E-08 7.493258282 -0.057405778 TSTTGVATTQS(ph)PTPR ddPTM_HeLa_Curcumin_4h_R1 4 TSTTGVATTQSPTPR 15 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 TSTTGVATTQS(0.954)PT(0.046)PR;TSTTGVATTQS(0.5)PT(0.5)PR;TSTTGVATTQS(0.741)PT(0.259)PR;TSTTGVATT(0.001)QS(0.925)PT(0.074)PR ;;; 244.23 3.05E-29 1134114000 8949.1 8694.3 8335.8 8302.4 8548.6 10733.6 7608.1 3424.87 9404.2 7129.6 TRUE FALSE FALSE 8240.769292 9445.796551 8644.732081 8268.046869 8446.663528 8507.330367 7821.56281 4469.097097 8372.582788 7377.353069 1.117036045 1.280377455 1.171793189 1.120733519 1.144945002 1.153168391 1.060212618 0.605785985 1.13490336 1 12.84888757 -4.263836535 4.500373096 1.097426593 0.573997958 0.809927068 0.074988986 0.079851451 4.082028952 0.012994946 0.131682051 5.45E-05 4.263836535 -0.523428634 TSVATSTEGKDKDVT(ph)LSPVK ddPTM_HeLa_Curcumin_4h_R1 1 TSVATSTEGKDKDVTLSPVK 20 2 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 TSVAT(0.001)S(0.002)T(0.002)EGKDKDVT(0.599)LS(0.395)PVK 77.027 0.0074611 51971000 2374.9 1704.5 1979 2254.2 2046.1 2225.4 2111.7 2332.7 2642.8 2198.1 TRUE FALSE FALSE 2186.924159 1851.829385 2052.343481 2244.872718 2021.701594 1763.826955 2170.948619 3043.929492 2352.891452 2274.483811 0.961503506 0.814175672 0.902333739 0.986981181 0.888861721 0.775484506 0.954479697 1.338294639 1.034472719 1 11.15132345 -4.262906933 6.817788853 0.943800198 1.344622181 0.704064099 0.07965286 0.050341031 16.44362873 0.011640617 0.093498403 5.46E-05 4.262906933 0.400821982 TSVLGGGEDGIEPVS(ph)PPEGMTEPGHSR ddPTM_HeLa_Curcumin_4h_R1 3 TSVLGGGEDGIEPVSPPEGMTEPGHSR 27 0 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 TSVLGGGEDGIEPVS(0.999)PPEGMT(0.001)EPGHSR;TSVLGGGEDGIEPVS(0.999)PPEGMTEPGHSR;TSVLGGGEDGIEPVS(0.913)PPEGMT(0.072)EPGHS(0.015)R ;; 126.62 3.68E-09 123639000 4488.8 3732.13 4697.7 4733.5 5752 6198.6 4585.2 1641.72 4466.2 3709.77 TRUE FALSE FALSE 4133.506743 4054.718687 4871.800895 4713.914031 5683.411157 4912.940487 4713.848372 2142.27287 3976.269034 3838.684231 1.076803012 1.056278256 1.269133016 1.228002552 1.480562301 1.279850123 1.227985447 0.558074783 1.035841657 1 11.90639617 -6.854993802 6.824295621 1.037984372 1.197321308 0.070690832 0.224900255 0.392172616 24.40091848 0.035584917 0.046936295 1.40E-07 6.854993802 0.159336937 TSVPENHAQSR ddPTM_HeLa_Curcumin_4h_R1 1 TSVPENHAQSR 11 0 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 0 0 75.739 0.016857 134350 161.81 0 60.901 0 60.004 272.77 66.226 57.947 70.35 0 FALSE FALSE TRUE 149.0025678 0 63.15804463 0 59.28849149 216.1944272 68.08412332 75.61477354 62.63278101 0 0 TSVPS(ph)PEQPQPYR ddPTM_HeLa_Curcumin_4h_R1 3 TSVPSPEQPQPYR 13 0 Q8TEH3 Q8TEH3 DENND1A DENN domain-containing protein 1A 1 0 TS(0.001)VPS(0.999)PEQPQPYR;T(0.001)S(0.003)VPS(0.997)PEQPQPYR;T(0.024)S(0.004)VPS(0.972)PEQPQPY(0.001)R ;; 151.66 0.00047982 65275000 4128.1 3353.93 3785.4 4100.78 3575.06 4322.3 2829.3 1640.69 4270.3 3978.1 TRUE FALSE FALSE 3801.356529 3643.828764 3925.690254 4083.812059 3532.429744 3425.806258 2908.682543 2140.928828 3801.858774 4116.338679 0.923480021 0.885211118 0.953684952 0.992098167 0.858148471 0.832245965 0.70661886 0.520105121 0.923602033 1 12.00714597 -3.889072403 0.684609408 0.960736936 1.54E-16 0.925809136 0.037973624 0.864322389 0.199255434 0.007220329 0.72374017 0.0001291 3.889072403 -0.960736936 TSVS(ph)PAPDK ddPTM_HeLa_Curcumin_4h_R1 2 TSVSPAPDK 9 0 O75362 O75362 ZNF217 Zinc finger protein 217 1 0 T(0.001)SVS(0.999)PAPDK;T(0.07)SVS(0.93)PAPDK ; 115.91 0.0072932 62673000 13731.8 11751.3 12724.3 12921.2 14087.9 17485.2 13919.7 3416.8 13493.8 11311.5 TRUE FALSE FALSE 12644.91354 12767.03001 13195.87375 12867.7355 13919.91099 13858.57242 14310.24932 4458.566591 12013.5639 11704.57378 1.080339513 1.090772739 1.127411728 1.099376683 1.189271071 1.184030506 1.222620284 0.380925156 1.026399092 1 13.51478478 -4.254328041 24.9905642 1.081290385 0.380924831 0.897036354 0.073726408 233.589116 820854.9961 0.012265656 0.166147406 5.57E-05 4.254328041 -0.700365554 TSVS(ph)QNVIPSSAQK ddPTM_HeLa_Curcumin_4h_R1 1 TSVSQNVIPSSAQK 14 0 Q03188;H0Y8J2;Q03188-2 Q03188 CENPC Centromere protein C 1 0 TSVS(0.491)QNVIPS(0.405)S(0.104)AQK 269.88 2.47E-50 13040000 4225.9 3151.1 3917.9 4365.6 3977.1 5245.8 3910.1 1563 4033.1 3334.8 TRUE FALSE FALSE 3891.415556 3423.467043 4063.100821 4347.536304 3929.67568 4157.761948 4019.806883 2039.551505 3590.67902 3450.684052 1.127722938 0.992112576 1.177476917 1.259905642 1.13881063 1.204909486 1.164930438 0.591057157 1.040570208 1 11.75266667 -4.256822527 24.93745406 1.098111089 0.591056945 0.768435916 0.08663307 199.6329788 1078257.146 0.013869868 0.149809933 5.54E-05 4.256822527 -0.507054143 TSVSQNVIPSS(ph)AQK ddPTM_HeLa_Curcumin_4h_R1 1 TSVSQNVIPSSAQK 14 0 Q03188;H0Y8J2;Q03188-2 Q03188 CENPC Centromere protein C 1 0 TSVSQNVIPS(0.185)S(0.815)AQK 291.13 4.86E-77 17318000 3995 3032.8 3881.4 4015.1 3805.6 4969.7 4477.4 1472 4198.5 3634.4 TRUE FALSE FALSE 3678.791534 3294.941718 4025.248098 3998.48658 3760.220706 3938.9282 4603.023794 1920.806024 3737.935054 3760.695129 0.978221155 0.876152308 1.070346827 1.063230717 0.999873847 1.04739365 1.223982172 0.51075824 0.993947907 1 11.87678364 -4.245320149 24.98166654 1.008465277 0.51075786 0.763438247 0.085772496 1189.38448 1843285.839 0.011520203 0.415361181 5.68E-05 4.245320149 -0.497707417 TSVSSVSAS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 2 TSVSSVSASPSR 12 0 P12036-2;P12036 P12036-2 NEFH Neurofilament heavy polypeptide 1 0 T(0.001)SVSSVS(0.002)AS(0.977)PS(0.02)R;TSVSSVSAS(0.954)PS(0.046)R ; 153.49 0.00039153 95239000 4236.7 3699.6 3946.5 4370.6 3815.3 4696.4 3862.6 2381.8 4189 3724.9 TRUE FALSE FALSE 3901.360724 4019.376939 4092.760762 4352.515615 3769.805039 3722.313701 3970.97416 3107.999856 3729.47718 3854.339998 1.012199424 1.04281847 1.061857741 1.129250564 0.978067592 0.965746069 1.030260476 0.806363698 0.967604618 1 11.91226812 -4.259238224 24.83084814 1.017022215 0.806363618 0.648757867 0.047273615 87.241289 984079.1549 0.006414627 0.057176107 5.51E-05 4.259238224 -0.210658597 EAPS(ph)PTCPDLGAK ddPTM_HeLa_Curcumin_4h_R1 1 EAPSPTCPDLGAK 13 0 O00257 O00257 CBX4 E3 SUMO-protein ligase CBX4 1 0 EAPS(0.868)PT(0.132)CPDLGAK 187.63 2.40E-05 26610000 3356 2234.1 2550.2 3569.8 2662.6 3655.4 3638.2 3795.4 2903 2213.5 TRUE FALSE FALSE 3090.369059 2427.205649 2644.712655 3555.029113 2630.850234 2897.228835 3740.2781 4952.599988 2584.548163 2290.41896 1.349259289 1.059721252 1.154685104 1.552130495 1.148632752 1.264934008 1.633010451 2.162311819 1.128417206 1 11.1613958 -1.000000002 0.676934757 1.169578175 110.0681586 0.805510526 0.147746534 84.10280816 0.455249394 0.028897906 13827.23933 0.1 1.000000002 108.8985804 up TT(ph)PDQELAPASEPVWERPWSVEEIRR ddPTM_HeLa_Curcumin_4h_R1 1 TTPDQELAPASEPVWERPWSVEEIRR 26 2 Q641Q2;E7ESD2;Q641Q2-2;A0A087WYF6;Q5T1D7 Q641Q2 FAM21A WASH complex subunit FAM21A 1 0 T(0.479)T(0.521)PDQELAPASEPVWERPWSVEEIRR 55.783 0.0028286 17529000 2900 2537 2464.9 2468.5 2116.7 2620.9 2217.6 2031.7 2998.1 2480.7 TRUE FALSE FALSE 2670.46194 2756.286975 2556.251362 2458.286001 2091.459735 2077.295796 2279.819888 2651.155977 2669.215931 2566.90414 1.040343462 1.073778694 0.995849951 0.957685159 0.814779057 0.80926115 0.88815934 1.032822354 1.039858049 1 11.3258137 -6.07572001 3.094082804 1.022983811 0.881151475 0.543108318 0.061457576 0.1547668 2.891190123 0.009524968 0.016937349 8.40E-07 6.07572001 -0.141832336 TT(ph)PNSGDVQVTEDAVR ddPTM_HeLa_Curcumin_4h_R1 1 TTPNSGDVQVTEDAVR 16 0 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 1 0 T(0.248)T(0.751)PNS(0.001)GDVQVTEDAVR 105.5 0.0057053 25862000 2921.3 2578.1 2578.9 2746.9 3479.1 3548.7 3346.5 2835.6 2720.2 2338.5 TRUE FALSE FALSE 2690.076022 2800.939476 2674.476303 2735.534056 3437.614005 2812.659618 3440.393783 3700.161387 2421.800866 2419.762701 1.111710674 1.157526511 1.105263876 1.130496827 1.420640959 1.16237002 1.421789741 1.529142252 1.000842299 1 11.24064986 -1 0.228059269 1.005083001 3.895162301 0.790579444 0.080642534 14.67887339 0.178005979 0.051595915 15.95547464 0.1 1 2.8900793 VDIET(ph)PNLEGTLTGPR ddPTM_HeLa_Curcumin_4h_R1 1 VDIETPNLEGTLTGPR 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VDIET(0.692)PNLEGT(0.307)LT(0.001)GPR 145.94 2.23E-05 0 2016.6 1495.1 1617 1993.8 1846.8 2889.6 2605.6 2447.5 1782.9 1425.6 TRUE FALSE FALSE 1856.983982 1624.329782 1676.927442 1985.550184 1824.778116 2290.264387 2678.706123 3193.731483 1587.320331 1475.139494 1.258853139 1.101136393 1.136792452 1.346008423 1.237020718 1.552574788 1.815900215 2.165036931 1.076047613 1 10.52663567 -1.000000001 0.407624739 1.096543235 20.47288844 0.952842093 0.076618171 11.51673042 0.134412589 0.02351532 182.2093581 0.1 1.000000001 19.37634521 up TT(ph)SPPEVSGYSYEK ddPTM_HeLa_Curcumin_4h_R1 1 TTSPPEVSGYSYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(0.369)T(0.489)S(0.14)PPEVS(0.002)GYS(0.001)YEK 98.676 0.017061 22180000 2266.8 2012.9 2068.9 2170.2 2214.7 2731.5 1807 1797.5 2536.5 2167.7 TRUE FALSE FALSE 2087.380388 2186.886107 2145.575254 2161.220287 2188.291149 2164.95611 1857.699557 2345.549475 2258.252296 2243.027414 0.930608505 0.974970744 0.956553291 0.963528254 0.975597149 0.965193781 0.828210812 1.045707003 1.006787649 1 11.13123154 TT(ph)SRSPVLSR ddPTM_HeLa_Curcumin_4h_R1 2 TTSRSPVLSR 10 1 O95819-3;E7EX83;G5E948;C9J840;H7C360;E7ENQ1;H7C0P6;G3XAA2;A0A0D9SG62;A0A0D9SEY1;O95819-4;O95819-2;O95819;O95819-5;O95819-6;E7EN19;H7C3Z6 O95819-3 MAP4K4 Mitogen-activated protein kinase kinase kinase kinase 4 1 0 T(0.018)T(0.49)S(0.49)RS(0.001)PVLSR;T(0.021)T(0.489)S(0.489)RSPVLSR ; 90.434 0.01558 209657000 5063.4 4123.4 3996.3 4211 4995.6 5808.1 3672.1 2315.8 4767.4 3520.7 TRUE FALSE FALSE 4662.626547 4479.808322 4144.406394 4193.575998 4936.030733 4603.434589 3775.129243 3021.876759 4244.428147 3643.044063 1.279871027 1.229688207 1.137621813 1.151118659 1.354919306 1.263623088 1.036256817 0.829492234 1.165077357 1 11.83092873 -4.413331993 3.281366945 1.166304839 0.827462937 0.573123255 0.096110169 0.214176949 3.798327558 0.018041672 0.144671056 3.86E-05 4.413331993 -0.338841902 TTAGS(ph)VDWTDQLGLR ddPTM_HeLa_Curcumin_4h_R1 2 TTAGSVDWTDQLGLR 15 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 T(0.005)T(0.017)AGS(0.582)VDWT(0.396)DQLGLR;T(0.004)T(0.004)AGS(0.965)VDWT(0.027)DQLGLR ; 232.78 4.43E-21 16515900 3401.8 2583.2 2718.9 2574.3 2764.6 4225.4 3428.1 2213.3 3431.6 2831.6 TRUE FALSE FALSE 3132.54394 2806.480297 2819.664826 2563.648229 2731.633951 3349.00441 3524.28326 2888.124981 3055.162065 2929.997889 1.069128395 0.957843795 0.962343637 0.874965896 0.932298948 1.143005741 1.202827918 0.985708895 1.04271818 1 11.51668391 -5.245494394 24.50411667 1.004265793 1.119745569 0.3596245 0.075447763 626.4795253 962765.5795 0.011576334 0.02939422 5.68E-06 5.245494394 0.115479777 TTCMSSQGS(ph)DDEQIKR ddPTM_HeLa_Curcumin_4h_R1 1 TTCMSSQGSDDEQIKR 16 1 E7EW69;E7EX04;B5ME97;Q9P0V9;Q9P0V9-2;C9JEW2;C9JNR7 E7EW69 10-Sep Septin-10 1 0 TTCMS(0.004)S(0.003)QGS(0.993)DDEQIKR 84.975 0.0043176 35160000 2626.2 2335.1 2330.9 1918.6 2522.8 2899.3 1708.9 1266.8 2502.8 2060.2 TRUE FALSE FALSE 2418.333499 2536.935639 2417.285204 1910.661342 2492.717258 2297.952498 1756.847135 1653.041488 2228.249102 2131.791797 1.13441355 1.190048504 1.133921806 0.896270144 1.16930615 1.077944151 0.824117598 0.775423515 1.045247057 1 11.05785083 -4.732220004 5.060999547 1.075533374 0.790846949 0.650663882 0.082524805 0.089798696 5.716563338 0.012345254 0.046405585 1.85E-05 4.732220004 -0.284686425 TTDGSLQNT(ph)SSEGSR ddPTM_HeLa_Curcumin_4h_R1 1 TTDGSLQNTSSEGSR 15 0 A8MQB8;Q06787-6;G3V0J0;Q06787-2;Q06787-4;Q06787-7 A8MQB8 FMR1 1 0 TTDGSLQNT(0.788)S(0.195)S(0.017)EGSR 134.81 0.0018347 7597600 3150.8 2488.7 2537.1 3057.8 2951.6 3898.9 3586.3 1610.4 2698 2566.4 TRUE FALSE FALSE 2901.410855 2703.812139 2631.127158 3045.147634 2916.404098 3090.22419 3686.921926 2101.403547 2402.03615 2655.582209 1.092570528 1.018161716 0.990791077 1.146696805 1.098216462 1.16367107 1.388366707 0.791315569 0.904523363 1 11.37481248 -6.247232812 23.98460267 1.038892945 1.134169679 0.108177537 0.144802511 824.4083661 1391825.6 0.019218106 0.031754198 5.66E-07 6.247232812 0.095276734 TTDLSIQPLS(ph)ADVK ddPTM_HeLa_Curcumin_4h_R1 1 TTDLSIQPLSADVK 14 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 TTDLS(0.011)IQPLS(0.989)ADVK 131.72 0.0010358 3673500 1042.2 614.75 771.78 854.08 837.92 960.01 784.25 7286.8 901.94 594.53 TRUE FALSE FALSE 959.7087703 667.8862507 800.3828457 850.5460433 827.9283513 760.8931045 806.2539443 9508.511776 802.9994385 615.1898732 1.560020429 1.085658721 1.301033844 1.382574844 1.34580946 1.236842701 1.3105774 15.45622285 1.305287154 1 9.264887945 -4.261439322 9.829091735 1.272383786 15.49442456 0.998826388 0.145771772 0.002347501 6.78529273 0.028342891 0.220012323 5.48E-05 4.261439322 14.22204077 GADTAPTLAPEALPS(ph)QGEVER ddPTM_HeLa_Curcumin_4h_R1 1 GADTAPTLAPEALPSQGEVER 21 0 Q8IZL8;C9JFV4 Q8IZL8 PELP1 "Proline-, glutamic acid- and leucine-rich protein 1" 1 0 GADTAPTLAPEALPS(1)QGEVER 183.65 4.36E-10 5600700 357.08 603.1 660.1 581.92 847.92 797.62 1067.1 1293.4 454.43 593.21 TRUE FALSE FALSE 328.8167412 655.2292766 684.5638867 579.5121692 837.8091078 632.184621 1097.039954 1687.751706 404.5801659 613.8240033 0.5356857 1.067454634 1.11524457 0.944101511 1.364901182 1.02991186 1.787222311 2.749569415 0.65911428 1 9.261681253 -1 0.568198802 0.818695716 99.86816679 0.884584958 0.20552311 33.56304187 0.265192399 0.043464253 4100.494301 0.1 1 99.04947107 up TTEEQVQAST(ph)PCPR ddPTM_HeLa_Curcumin_4h_R1 4 TTEEQVQASTPCPR 14 0 Q14137 Q14137 BOP1 Ribosome biogenesis protein BOP1 1 0 TTEEQVQAS(0.036)T(0.964)PCPR;TTEEQVQAST(1)PCPR;TTEEQVQAS(0.027)T(0.973)PCPR;TTEEQVQAS(0.173)T(0.827)PCPR ;;; 201.3 1.87E-08 64025000 10412.4 9904.1 10447.1 10631.5 9427.1 16948.7 16151.1 8911.7 12205.1 9235.5 TRUE FALSE FALSE 9588.247553 10760.16627 10834.27872 10587.50967 9314.68799 13433.34857 16604.2564 11628.83631 10866.23107 9556.432938 1.003329131 1.125960528 1.133715769 1.107893472 0.974703433 1.405686479 1.737495204 1.21685951 1.137059312 1 13.2222565 -5.185449755 4.701318014 1.027943078 1.495334612 0.620945891 0.134996422 0.082011077 3.36509713 0.017096849 0.045058575 6.52E-06 5.185449755 0.467391534 TTGIVMDSGDGVTHTVPIYEGYALPHAILR ddPTM_HeLa_Curcumin_4h_R1 4 TTGIVMDSGDGVTHTVPIYEGYALPHAILR 30 0 P60709;A0A2R8Y793;A0A2R8YEA7;P63261;I3L3I0;I3L1U9;I3L4N8 P60709;P63261 ACTB;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 0 0 ;;; ;;; 135.12 1.80E-12 417382000 2787.13 2991.8 2816.38 1597.3 2514.39 12099.6 7534.2 6727.6 4010.99 2700.93 FALSE FALSE TRUE 2566.52572 3250.397861 2920.75752 1590.690796 2484.407541 9590.006569 7745.589375 8778.81427 3570.994432 2794.787116 0.918326016 1.163021628 1.045073345 0.569163492 0.888943393 3.431390718 2.771441635 3.141138807 1.277733968 1 11.44852268 -5.266225089 24.99693229 0.948187129 3.08033556 0.946769897 0.231784288 49.51594779 258634.5649 0.028090642 0.064771384 5.42E-06 5.266225089 2.132148431 TTGMSQS(ph)TELLPDATDEEVAPPKPPLPGIR ddPTM_HeLa_Curcumin_4h_R1 1 TTGMSQSTELLPDATDEEVAPPKPPLPGIR 30 1 Q13905-2;Q13905;Q13905-4;Q13905-3 Q13905-2 RAPGEF1 Rap guanine nucleotide exchange factor 1 1 0 T(0.043)T(0.018)GMS(0.09)QS(0.553)T(0.285)ELLPDAT(0.011)DEEVAPPKPPLPGIR 59.332 0.0046138 6059500 757.78 490.82 567.45 469.74 485.36 552.38 417.83 345.22 806.66 512.8 TRUE FALSE FALSE 697.8009134 533.2442937 588.4801962 467.7963403 479.572399 437.8101614 429.5531853 450.4759888 718.1714162 530.6197618 1.315067707 1.004946163 1.10904312 0.881603691 0.903796718 0.825092077 0.809531073 0.848961952 1.353457726 1 9.051534597 -6.259458584 1.500112983 1.144283061 0.834701423 0.665364939 0.108038305 0.219315181 0.966517264 0.0203777 0.037813689 5.50E-07 6.259458584 -0.309581638 TTGQVVAMK(ac)K ddPTM_HeLa_Curcumin_4h_R1 5 TTGQVVAMKK 10 1 A0A087WZZ9;P06493;E5RIU6;A0A024QZP7;P06493-2 A0A087WZZ9 CDK1;CDC2 Cyclin-dependent kinase 1 0 1 ;;;; TTGQVVAMK(1)K;TTGQVVAMK(1)K;TTGQVVAMK(1)K;TTGQVVAMK(1)K;TTGQVVAMK(1)K 143.61 5.75E-06 60020700 18084.75 11975.4 14885.56 13113.93 15299.16 17532.13 13926.25 17275.17 13742.63 13832.64 FALSE TRUE FALSE 16653.32295 13010.50021 15437.23195 13059.66803 15116.72751 13895.76861 14316.98309 22542.28981 12235.09787 14313.32321 1.163484029 0.908978301 1.078521858 0.91241341 1.056129823 0.970827557 1.000255698 1.574916564 0.854804834 1 13.80507105 -4.258548558 24.92540922 1.04418272 1.574916764 0.744758555 0.098145183 95.49904806 823371.8419 0.012444794 0.115908819 5.51E-05 4.258548558 0.530734044 TTHFVEGGDAGNREDQINR ddPTM_HeLa_Curcumin_4h_R1 2 TTHFVEGGDAGNREDQINR 19 1 P18124;A8MUD9 P18124 RPL7 60S ribosomal protein L7 0 0 ; ; 59.15 0.0073383 26620000 2245.82 2413.11 2257.39 2440.2 2104.54 2810.6 2154.63 1907.86 3024.7 2435.48 FALSE FALSE TRUE 2068.060977 2621.688476 2341.050859 2430.103099 2079.444735 2227.649878 2215.083119 2489.557731 2692.897977 2520.112749 0.820622402 1.040306025 0.928946874 0.964283483 0.825139564 0.883948498 0.878961912 0.987875536 1.068562499 1 11.29927257 -5.806181457 24.99999364 0.927938836 0.892190961 0.04706811 0.080204357 382.7514794 213864.4285 0.012234754 0.022177465 1.56E-06 5.806181457 -0.035747875 TTHLAGALS(ph)PGEAWPFESV ddPTM_HeLa_Curcumin_4h_R1 2 TTHLAGALSPGEAWPFESV 19 0 Q9Y3X0 Q9Y3X0 CCDC9 Coiled-coil domain-containing protein 9 1 0 T(0.001)T(0.001)HLAGALS(0.93)PGEAWPFES(0.069)V;TTHLAGALS(0.964)PGEAWPFES(0.035)V ; 92.952 0.0016365 174192000 9713.1 8053 8596.9 8243.8 8090.8 14870.2 11019.2 12113.5 10577.6 8501.8 TRUE FALSE FALSE 8944.297886 8749.065437 8915.508677 8209.68934 7994.322494 11785.9529 11328.3691 15806.85039 9417.263744 8797.236917 1.016716723 0.994524249 1.013444194 0.933212259 0.908731067 1.339733488 1.287718997 1.796797169 1.070479724 1 13.10283475 -4.078116155 0.96132313 0.99722692 2.424323324 0.886268686 0.087031992 0.553454814 0.308806842 0.012199477 0.887560786 8.35E-05 4.078116155 1.427096404 TASES(ph)ISNLSEAGS(ph)IK ddPTM_HeLa_Curcumin_4h_R1 1 TASESISNLSEAGSIK 16 0 F5H1T5;F5H6A0;J3KP58;P30622-2;P30622-1;P30622 F5H1T5 CLIP1 CAP-Gly domain-containing linker protein 1 2 0 T(0.011)AS(0.088)ES(0.799)IS(0.11)NLS(0.068)EAGS(0.923)IK 87.676 0.017569 8204100 3058.2 3692.2 3691.3 3969.6 4543.6 5642.6 5801.3 7997.4 4165.9 3368 TRUE FALSE FALSE 2816.140243 4011.337316 3828.102825 3953.174847 4489.420538 4472.261155 5964.068865 10435.77044 3708.911193 3485.037749 0.808065922 1.151016891 1.098439415 1.134327698 1.288198539 1.28327481 1.711335513 2.994449758 1.064238456 1 11.76695857 -1 0.658450819 0.946564622 192.4645211 0.957933407 0.12116934 29.84227096 0.173129722 0.022994304 8363.211762 0.1 1 191.5179565 up TTHS(ph)PYEER ddPTM_HeLa_Curcumin_4h_R1 1 TTHSPYEER 9 0 Q8NDT2;Q8NDT2-2 Q8NDT2 RBM15B Putative RNA-binding protein 15B 1 0 T(0.222)T(0.077)HS(0.701)PYEER 94.402 0.0077545 49364000 778.03 688.07 875.65 932.29 684.52 891.4 604.52 371.22 642.11 823.63 TRUE FALSE FALSE 716.4481045 747.5437048 908.1023593 928.432431 676.3575461 706.5135919 621.4812042 484.4032691 571.6721395 852.2510812 0.840653794 0.877140225 1.065533831 1.089388387 0.79361301 0.828997003 0.729223134 0.568380938 0.670779013 1 9.735134714 -4.567575028 1.090215116 0.93727296 0.499954413 0.438240173 0.120059367 0.584065443 0.774027165 0.015189389 0.257903185 2.71E-05 4.567575028 -0.437318547 TTIFS(ph)PEGR ddPTM_HeLa_Curcumin_4h_R1 1 TTIFSPEGR 9 0 H0YLS6;H0YLC2;H0YMI6;H0YMA1;H0YMZ1;H0YL69;P25789 H0YLS6 PSMA4 Proteasome subunit alpha type;Proteasome subunit alpha type-4 1 0 T(0.005)T(0.005)IFS(0.991)PEGR 123.11 0.0054294 23571000 5541.9 4474.2 4296.1 4916.6 4747.7 6843.7 6014.5 1960.6 4880.6 3108.5 TRUE FALSE FALSE 5103.252767 4860.929911 4455.317245 4896.256412 4691.086778 5424.239476 6183.250683 2558.377915 4345.210391 3216.520144 1.586575721 1.511238759 1.385135813 1.522221591 1.45843538 1.686368881 1.922341663 0.795386878 1.350904144 1 11.65128501 -9.301747862 0.848482017 0.973832097 1.508767317 0.101043059 0.291278356 0.608544275 0.723849231 0.217967673 0.048308377 4.99E-10 9.301747862 0.53493522 TTIPEEEEEEEEAAGVVVEEELFHQQGT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 6 TTIPEEEEEEEEAAGVVVEEELFHQQGTPR 30 0 P20700 P20700 LMNB1 Lamin-B1 1 0 TTIPEEEEEEEEAAGVVVEEELFHQQGT(1)PR;TTIPEEEEEEEEAAGVVVEEELFHQQGT(1)PR;TTIPEEEEEEEEAAGVVVEEELFHQQGT(1)PR;TTIPEEEEEEEEAAGVVVEEELFHQQGT(1)PR;TTIPEEEEEEEEAAGVVVEEELFHQQGT(1)PR;TTIPEEEEEEEEAAGVVVEEELFHQQGT(1)PR ;;;;; 137.84 2.73E-12 307743300 12762.95 10433.82 10330.26 10703.68 9760.78 11859.65 8712.73 4827.13 11641.62 9986.49 TRUE FALSE FALSE 11752.74904 11335.67291 10713.10852 10659.39101 9644.389073 9399.824904 8957.185755 6298.899716 10364.56341 10333.51978 1.137342289 1.096980811 1.036733731 1.031535356 0.933311135 0.909644061 0.866808787 0.609559942 1.003004168 1 13.33504413 -3.717511897 0.616066011 1.067208366 1.29E-13 0.881930619 0.048514778 1.620599447 0.263896217 0.010700761 1.426173805 0.000191641 3.717511897 -1.067208366 TTIPEEEEEEEEAAGVVVEEELFHQQGTPR ddPTM_HeLa_Curcumin_4h_R1 2 TTIPEEEEEEEEAAGVVVEEELFHQQGTPR 30 0 P20700 P20700 LMNB1 Lamin-B1 0 0 ; ; 161 9.46E-14 3964700 1358.05 846.12 1000.64 970.6 1041.26 1090.99 675.47 574.22 967.34 1077.26 FALSE FALSE TRUE 1250.558909 919.2548426 1037.724599 966.5839144 1028.843655 864.706376 694.4218703 749.2970346 861.2252222 1114.694705 1.121884678 0.824669606 0.930949608 0.867128829 0.922982454 0.775733815 0.622970458 0.672199331 0.772610849 1 10.12243292 -5.238275379 0.491013639 1.053420632 0.532727906 0.335729368 0.116375961 0.754029919 0.217850007 0.021031411 0.192204344 5.78E-06 5.238275379 -0.520692726 TTK(ac)LGQR ddPTM_HeLa_Curcumin_4h_R1 1 TTKLGQR 7 1 O60885;O60885-2;O60885-3;M0QZD9 O60885 BRD4 Bromodomain-containing protein 4 0 1 TTK(1)LGQR 107.29 0.015397 5871100 3154.2 2010.1 2839 1509.5 2196.1 2792.6 1265.8 832.07 1619.6 2234.1 FALSE TRUE FALSE 2904.541742 2183.844087 2944.215837 1503.254089 2169.912942 2213.383281 1301.314941 1085.764313 1441.933932 2311.734809 1.256433796 0.944677598 1.273595841 0.650270993 0.938651325 0.957455532 0.562917051 0.469675115 0.623745391 1 11.17476019 -4.282683217 0.532919431 1.115576157 9.82E-15 0.292785858 0.224158116 1.872261822 0.360824591 0.034016276 1.289330306 5.22E-05 4.282683217 -1.115576157 TTKPPYPGS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 2 TTKPPYPGSPVK 12 1 Q96T17;Q96T17-2;Q96T17-5;Q96T17-4 Q96T17 MAP7D2 MAP7 domain-containing protein 2 1 0 TTKPPYPGS(1)PVK;TTKPPYPGS(1)PVK ; 98.508 0.0044302 792110000 14718.8 11903.4 14426.3 14074.7 14308.1 15351.6 14036.5 5721.9 12900.2 10573.3 TRUE FALSE FALSE 13553.79145 12932.27686 14960.95137 14016.46262 14137.48525 12167.50511 14430.32641 7466.48097 11485.08033 10940.72139 1.238838918 1.182031458 1.367455658 1.281127827 1.292189496 1.112130058 1.318955661 0.682448689 1.049755307 1 13.41742025 -3.136777908 11.70078766 1.149403007 1.163264604 0 0.193593491 0 0 0.025026396 0 0.000729831 3.136777908 0.013861597 TQTPPVSPAPQPT(ph)EERLPSSPVYEDAASFK ddPTM_HeLa_Curcumin_4h_R1 2 TQTPPVSPAPQPTEERLPSSPVYEDAASFK 30 1 Q14247;Q14247-3;Q14247-2;H0YEV2;H0YCD9 Q14247 CTTN Src substrate cortactin 1 0 T(0.021)QT(0.064)PPVS(0.389)PAPQPT(0.514)EERLPS(0.005)S(0.006)PVY(0.002)EDAASFK;T(0.033)QT(0.119)PPVS(0.124)PAPQPT(0.684)EERLPS(0.015)S(0.018)PVY(0.007)EDAASFK ; 75.156 5.37E-05 300038000 6985.3 5932.3 5869.8 5884.4 5333 7143.2 6007.5 2186.42 7610.9 6264.4 TRUE FALSE FALSE 6432.406134 6445.061578 6087.339952 5860.051912 5269.407458 5661.6198 6176.054282 2853.049393 6776.003312 6482.087434 0.992335602 0.994287973 0.939101796 0.904037777 0.812918294 0.873425398 0.95278787 0.440143615 1.045342782 1 12.66224277 -4.038277374 2.055325578 0.967365844 1.75E-24 0.818660809 0.070285646 0.54028234 1.408544251 0.010763537 1.204214283 9.16E-05 4.038277374 -0.967365844 down TTKT(ph)PEDGDYSYEIIEK ddPTM_HeLa_Curcumin_4h_R1 2 TTKTPEDGDYSYEIIEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(0.007)T(0.008)KT(0.985)PEDGDYSYEIIEK;T(0.22)T(0.242)KT(0.538)PEDGDYSYEIIEK ; 119.38 0.00054883 172522000 11376.6 9264.5 10061 10660 9918.2 12286.1 9722.3 13915.8 12300.4 9019.2 TRUE FALSE FALSE 10476.13011 10065.2821 10433.86951 10615.89174 9799.931943 9737.824367 9995.081572 18158.66336 10951.07689 9332.616529 1.122528722 1.078505912 1.118000453 1.137504334 1.050073354 1.04341846 1.070983849 1.945720507 1.173419786 1 13.1880659 -4.261448823 9.982245674 1.068735851 1.9478739 0.960854823 0.05178595 0.009742518 31.40186574 0.00740084 0.057382611 5.48E-05 4.261448823 0.879138049 TTLASAVACLEGKS(ph)PGEK ddPTM_HeLa_Curcumin_4h_R1 1 TTLASAVACLEGKSPGEK 18 1 J3KNN7;Q7Z569 J3KNN7 BRAP BRCA1-associated protein 1 0 TTLASAVACLEGKS(1)PGEK 83.871 0.0022015 20513000 1452.6 1016.3 1068.3 1411.6 1124.5 1062.1 758.74 688.12 1383.9 1178.5 TRUE FALSE FALSE 1337.625177 1104.144443 1107.892138 1405.759173 1111.091072 841.8084877 780.0282024 897.9246203 1232.089632 1219.452787 1.09690608 0.905442552 0.908515811 1.152778679 0.911139065 0.690316588 0.639654286 0.736334059 1.010362718 1 10.25201819 -5.384438743 3.335690298 1.030559109 0.681795356 0.780770169 0.075982153 0.08197096 1.692117007 0.011606324 0.028018083 4.13E-06 5.384438743 -0.348763752 KCS(ph)LPAEEDSVLEK ddPTM_HeLa_Curcumin_4h_R1 1 KCSLPAEEDSVLEK 14 1 E7EVA0;P27816;P27816-6 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 KCS(1)LPAEEDSVLEK 99.011 0.0026896 10304000 5324.5 4123 4322.9 4510.4 4693.7 5415.8 3938.3 1645.1 4864.9 4566.1 TRUE FALSE FALSE 4903.060207 4479.373748 4483.110477 4491.73716 4637.730693 4292.502031 4048.798099 2146.683417 4331.232641 4724.771635 1.037734855 0.948061429 0.948852309 0.950678151 0.981577746 0.908509948 0.856929903 0.454346492 0.916707298 1 12.20602889 -4.038225781 1.25807929 1.000148582 2.23E-21 0.917337487 0.044883298 0.388318987 0.360350348 0.006266629 0.571450442 9.16E-05 4.038225781 -1.000148582 down TTPES(ph)PPYSSGSYDSIK ddPTM_HeLa_Curcumin_4h_R1 1 TTPESPPYSSGSYDSIK 17 0 A0A087WTU5;Q96MY1-2;Q96MY1;A0A087X0N3 A0A087WTU5 NOL4L Nucleolar protein 4-like 1 0 TTPES(0.999)PPYSSGSYDSIK 178.01 1.02E-05 43160000 3632.3 2595.4 3131 2724.8 3238.2 3665.5 2599.6 1663.2 3016 2740.6 TRUE FALSE FALSE 3344.799622 2819.734811 3247.037614 2713.5255 3199.58658 2905.233981 2672.53778 2170.302024 2685.152346 2835.835646 1.179475837 0.994322367 1.145002045 0.956869804 1.128269399 1.024471917 0.942416315 0.765313049 0.946864586 1 11.46955821 -4.197297062 1.223578899 1.078117628 0.58593214 0.525160204 0.07938254 0.879640586 0.986183983 0.011725382 0.566061384 6.35E-05 4.197297062 -0.492185488 TTPKEPTEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 TTPKEPTEKK 10 2 P26358;P26358-2 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 0 1 ; TTPKEPTEK(1)K;TTPKEPTEK(1)K 84.31 0.007353 12086600 6319.4 6872.4 6267 6923.1 5545.6 9171.9 6998.9 6967.7 7934.9 7700.5 FALSE TRUE FALSE 5819.212822 7466.419633 6499.260533 6894.454047 5479.472342 7269.544551 7195.270297 9092.119655 7064.461322 7968.091802 0.73031448 0.937039861 0.81566085 0.865257858 0.687676859 0.912331927 0.903010467 1.141066127 0.886593867 1 12.96001855 -4.170057922 2.102453314 0.859075449 1.265625289 0.486982412 0.087884743 0.820263418 3.22670861 0.015858385 0.683643434 6.76E-05 4.170057922 0.40654984 TTPNK(ac)GNK(ac)ALK(ac)VK ddPTM_HeLa_Curcumin_4h_R1 1 TTPNKGNKALKVK 13 3 I3L2F8;O15525 I3L2F8 MAFG Transcription factor MafG 0 3 TTPNK(1)GNK(1)ALK(1)VK 110.66 0.0057986 1527600 598.71 349.95 693.55 507.3 562.25 1007.7 706.27 385.92 501.94 496.63 FALSE TRUE FALSE 551.3214717 380.1981187 719.2535731 505.200927 555.545536 798.6916609 726.0860354 503.5852314 446.8784378 513.8878555 1.07284394 0.739846475 1.399631389 0.983095673 1.081063757 1.554213925 1.412927018 0.97995161 0.869603033 1 9.005309748 -5.443093216 9.427530178 1.037646015 1.325045428 0.296179579 0.208069309 0.401734824 45.26790953 0.02662185 0.059565664 3.61E-06 5.443093216 0.287399414 TTPPT(ph)QKPPSPPMSGK ddPTM_HeLa_Curcumin_4h_R1 1 TTPPTQKPPSPPMSGK 16 1 H7C3Q7;H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9;E9PEZ7 H7C3Q7 ABI2 Abl interactor 2 1 0 T(0.019)T(0.105)PPT(0.857)QKPPS(0.018)PPMSGK 90.229 0.0045939 237990000 2954 2460.4 2272 2837.7 2500.4 3426.6 2663.2 2546.9 3158 2554.7 TRUE FALSE FALSE 2720.187783 2673.066013 2356.202319 2825.958349 2470.584363 2715.884534 2737.922224 3323.438086 2811.575301 2643.475635 1.029019427 1.01119374 0.89132742 1.069031359 0.934596987 1.027391552 1.035728186 1.257222893 1.063590397 1 11.36822031 -4.214899351 2.62892446 1.004212267 1.32703333 0.683196422 0.051546891 0.225354175 1.801904928 0.006238778 0.167147104 6.10E-05 4.214899351 0.322821063 TTPPTQKPPS(ph)PPMSGK ddPTM_HeLa_Curcumin_4h_R1 2 TTPPTQKPPSPPMSGK 16 1 H7C3Q7;H0Y6B5;B7Z836;E7EW77;E7EP65;A0A0C4DG21;F8WAL6;Q9NYB9-3;Q9NYB9-2;Q9NYB9-4;Q9NYB9;E9PEZ7 H7C3Q7 ABI2 Abl interactor 2 1 0 TTPPT(0.002)QKPPS(0.998)PPMSGK;TTPPTQKPPS(0.999)PPMS(0.001)GK ; 115.66 0.00067927 223900000 6110.8 4164.52 4691.7 4890.12 4679.63 5909.2 4558.7 4304.7 5948 4893.1 TRUE FALSE FALSE 5627.123732 4524.482552 4865.578529 4869.885979 4623.828469 4683.56531 4686.604853 5617.183214 5295.519281 5063.134861 1.11139124 0.893612885 0.96098142 0.961832168 0.91323431 0.9250327 0.925633028 1.109427927 1.04589734 1 12.3058152 -7.261352989 24.99999996 1.052601419 0.95215296 0.342580687 0.061282595 6.712103657 1942440.897 0.011157767 0.013217698 5.48E-08 7.261352989 -0.100448459 TTPQQGASGPGRS(ph)PVGQAR ddPTM_HeLa_Curcumin_4h_R1 2 TTPQQGASGPGRSPVGQAR 19 1 A0A2R8YFR7;Q12774;A0A2R8YF49;H0Y895 A0A2R8YFR7 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 0 TTPQQGAS(0.012)GPGRS(0.988)PVGQAR;TTPQQGAS(0.098)GPGRS(0.902)PVGQAR ; 73.953 0.0033921 12588100 1144.73 816.41 1210.2 1437.48 1127.71 725.02 656.17 558.59 1181.41 1283.06 TRUE FALSE FALSE 1054.123413 886.9768425 1255.051077 1431.532089 1114.262795 574.6426793 674.5803642 728.9015196 1051.812279 1327.646239 0.793979135 0.668082217 0.945320402 1.07824814 0.839276881 0.43282816 0.508102493 0.549017877 0.792238359 1 10.37465507 -5.324845461 5.399930959 0.897148081 0.498063217 0.697863224 0.113338015 0.092210361 5.438210354 0.018168326 0.041710277 4.73E-06 5.324845461 -0.399084864 TTPS(ph)YVAFTDTER ddPTM_HeLa_Curcumin_4h_R1 1 TTPSYVAFTDTER 13 0 P11142;E9PKE3;E9PNE6;P11142-2;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PPY6;E9PN25;E9PI65;A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;Q53FA3;P34931;P17066;P48741;P54652 P11142;A0A0G2JIW1;P17066;P54652 HSPA8;HSPA1B;HSPA1A;HSPA1L;HSPA6;HSPA7;HSPA2 Heat shock cognate 71 kDa protein;Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 1-like;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7;Heat shock-related 70 kDa protein 2 1 0 T(0.015)T(0.199)PS(0.774)YVAFT(0.012)DTER 234.83 7.27E-66 0 532.68 462.52 385.24 594.71 746.39 732.97 557.84 247.77 741.8 426.94 TRUE FALSE FALSE 490.5178159 502.4981679 399.5173333 592.2492476 737.4897867 580.9437597 573.4914891 323.3139324 660.4263959 441.7761332 1.110331181 1.137449785 0.904343407 1.340609424 1.669374444 1.315018436 1.298149551 0.731850157 1.49493453 1 8.78717167 -6.245475191 24.33970727 1.051108876 1.297086043 0.022667808 0.263135468 681.586085 1039175.85 0.033218337 0.054955256 5.68E-07 6.245475191 0.245977167 TTPSVVAFTADGER ddPTM_HeLa_Curcumin_4h_R1 2 TTPSVVAFTADGER 14 0 P38646;D6RJI2;A0A3B3ITI4;D6RA73 P38646 HSPA9 "Stress-70 protein, mitochondrial" 0 0 ; ; 166.11 6.71E-05 11244600 812.68 613.94 829.2 963.74 726.71 863.31 709.96 646.5 755.03 556.08 FALSE FALSE TRUE 748.3555205 667.0062379 859.9308814 959.7522992 718.0444579 684.2497745 729.8795668 843.6148739 672.205098 575.4037386 1.300574658 1.159196914 1.494482611 1.667963266 1.247896754 1.189164631 1.26846511 1.466126855 1.168232065 1 9.168430785 -8.812731667 0.55427065 0.975724762 1.362746801 0.315948163 0.153367596 0.756050057 0.415976766 0.144207476 0.040624922 1.54E-09 8.812731667 0.387022039 TTPSYVAFTDTER ddPTM_HeLa_Curcumin_4h_R1 6 TTPSYVAFTDTER 13 0 P11142;E9PKE3;E9PNE6;P11142-2;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PPY6;E9PN25;E9PI65;A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;Q53FA3;P34931;P17066;P48741;P54652 P11142;A0A0G2JIW1;P17066;P54652 HSPA8;HSPA1B;HSPA1A;HSPA1L;HSPA6;HSPA7;HSPA2 Heat shock cognate 71 kDa protein;Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 1-like;Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7;Heat shock-related 70 kDa protein 2 0 0 ;;;;; ;;;;; 316.83 6.93E-155 283510000 8765.73 7483.01 8192.25 8542.1 8386.14 10257.28 7842.27 7863.8 9573.3 8127.49 FALSE FALSE TRUE 8071.913221 8129.808041 8495.861992 8506.755054 8286.140758 8129.804505 8062.30299 10261.43642 8523.132941 8409.919673 0.959808599 0.96669271 1.010219161 1.011514424 0.985281796 0.96669229 0.958665874 1.220158672 1.013461873 1 13.03787631 -4.25803965 24.99687061 0.981902564 1.220158761 0.916262327 0.021223572 65.50160013 481584.9924 0.003053105 0.029688969 5.52E-05 4.25803965 0.238256197 TTQFSCTLGEK ddPTM_HeLa_Curcumin_4h_R1 2 TTQFSCTLGEK 11 0 I6L8B7;Q01469 I6L8B7 FABP5 "Fatty acid-binding protein, epidermal" 0 0 ; ; 172.11 5.16E-09 5609900 2613.4 2257.85 2692.7 2616.8 2805.7 2896.4 2609.3 2302.5 2461.4 2134 FALSE FALSE TRUE 2406.546632 2453.008493 2792.493831 2605.972375 2772.24386 2295.653991 2682.509935 3004.521651 2191.390578 2208.156341 1.089844314 1.110885333 1.264626865 1.180157549 1.255456332 1.039624753 1.214818845 1.360647158 0.992407348 1 11.10862661 -1.000000286 0.051238272 0.605606765 2.192673887 0.57024163 0.077123227 227.9985086 0.889988682 6.47225893 28.54642866 0.099999934 1.000000286 1.587067122 TTQPSINESES(ph)DPFEVVRDDFK ddPTM_HeLa_Curcumin_4h_R1 1 TTQPSINESESDPFEVVRDDFK 22 1 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101;F5GWN9 Q76FK4-2 NOL8 Nucleolar protein 8 1 0 TTQPS(0.012)INES(0.105)ES(0.883)DPFEVVRDDFK 61.361 0.003655 10615000 1656.1 951.19 1191.2 1130 1034.9 1632.2 1034.8 416.97 1070.1 1429.5 TRUE FALSE FALSE 1525.017937 1033.406625 1235.34692 1125.324359 1022.559493 1293.663321 1063.833703 544.1022335 952.7127073 1479.175019 1.030992221 0.698637154 0.835159399 0.76077837 0.691303923 0.874584349 0.719207457 0.367841687 0.644083827 1 10.53057705 -3.875719487 0.249007998 1.051754072 2.18E-15 0.139132075 0.167816193 5.813034277 0.245467345 0.083136878 1.941606865 0.000133131 3.875719487 -1.051754072 TTQSMQDFPVVDS(ph)EEEAEEEFQK ddPTM_HeLa_Curcumin_4h_R1 5 TTQSMQDFPVVDSEEEAEEEFQK 23 0 Q9UBB9 Q9UBB9 TFIP11 Tuftelin-interacting protein 11 1 0 TTQSMQDFPVVDS(1)EEEAEEEFQK;TTQSMQDFPVVDS(1)EEEAEEEFQK;TTQSMQDFPVVDS(1)EEEAEEEFQK;TTQSMQDFPVVDS(1)EEEAEEEFQK;TTQSMQDFPVVDS(1)EEEAEEEFQK ;;;; 180.21 1.26E-10 47486900 21013.94 17929.62 19217.29 18162.32 20943.04 23210.66 19711.05 14827.79 19251.31 16863.12 TRUE FALSE FALSE 19350.66448 19479.37646 19929.49967 18087.16913 20693.30793 18396.50748 20264.08901 19348.71491 17139.48946 17449.11216 1.108977024 1.116353444 1.142149783 1.03656673 1.185923257 1.054294757 1.161324933 1.108865295 0.982255676 1 14.09086601 -9.13391907 0.570050368 0.984057315 1.117643435 0.5664615 0.0428016 0.667945577 0.331425391 0.046865574 0.009211087 7.35E-10 9.13391907 0.13358612 TTRT(ph)PDTSTYCYETAEK ddPTM_HeLa_Curcumin_4h_R1 1 TTRTPDTSTYCYETAEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(0.008)T(0.002)RT(0.991)PDTSTYCYETAEK 170.47 0.00061273 104270000 4249.9 3926.4 3749.3 4368.8 3675.2 5206.2 4205.3 2629.5 4862.9 3883.5 TRUE FALSE FALSE 3913.515931 4265.78052 3888.252356 4350.723063 3631.37564 4126.375434 4323.2894 3431.222445 4329.452036 4018.451336 0.973886605 1.061548384 0.967599712 1.082686513 0.903675405 1.026857137 1.075859588 0.853866865 1.077393173 1 11.9724239 -4.239997629 24.01107855 0.998783436 0.853866612 0.37678713 0.058759526 2280.900176 2554149.798 0.006697094 0.386729017 5.75E-05 4.239997629 -0.144916824 TTRT(ph)PEEGGYSYDISEK ddPTM_HeLa_Curcumin_4h_R1 3 TTRTPEEGGYSYDISEK 17 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(0.227)T(0.227)RT(0.546)PEEGGYSYDISEK;T(0.09)T(0.09)RT(0.821)PEEGGYSYDISEK;T(0.054)T(0.054)RT(0.892)PEEGGYSYDISEK ;; 163.41 0.00010295 779445500 7936.73 5872.24 6566.43 6773.64 6707.18 8265.22 6417.86 4882.5 7405.6 6320.5 TRUE FALSE FALSE 7308.529446 6379.810259 6809.787672 6745.612472 6627.201259 6550.920204 6597.927879 6371.151774 6593.224208 6540.136905 1.117488755 0.975485736 1.041230141 1.031417625 1.013312314 1.001648788 1.008836355 0.974161836 1.008117155 1 12.67510512 -5.772628198 0.832549809 1.050775981 0.990117222 0.038025008 0.038156927 0.902142014 1.151066314 0.008789397 0.031228612 1.69E-06 5.772628198 -0.06065876 TTS(ph)FAESCKPVQQPSAFGSMK ddPTM_HeLa_Curcumin_4h_R1 2 TTSFAESCKPVQQPSAFGSMK 21 1 P49841;P49841-2;A0A3B3ITW1 P49841 GSK3B Glycogen synthase kinase-3 beta 1 0 T(0.146)T(0.036)S(0.76)FAES(0.058)CKPVQQPSAFGSMK;T(0.406)T(0.085)S(0.507)FAES(0.002)CKPVQQPSAFGSMK ; 114.39 7.01E-06 159174000 2829.2 2606.5 2604.9 3542 2660 4883.1 3805.5 2554.1 3744.5 2876.3 TRUE FALSE FALSE 2605.265835 2831.794246 2701.439886 3527.344143 2628.281237 3870.290016 3912.272088 3332.833332 3333.737718 2976.251211 0.875351457 0.95146345 0.907665279 1.185163446 0.883084475 1.300390909 1.314496597 1.119809148 1.120113015 1 11.53928059 -5.258883615 24.98902775 0.95351439 1.251858669 0.51630755 0.109758575 101.2010019 989486.708 0.013838595 0.033585728 5.51E-06 5.258883615 0.298344279 TTS(ph)FFSR ddPTM_HeLa_Curcumin_4h_R1 1 TTSFFSR 7 0 Q9BZ67-2;Q9BZ67-3;Q9BZ67 Q9BZ67-2 FRMD8 FERM domain-containing protein 8 1 0 T(0.003)T(0.131)S(0.866)FFSR 104.01 0.017686 7316100 3731.8 3255.1 3221.4 3966.4 3689.9 3965.2 2974.9 3079.5 4078.8 3793.4 TRUE FALSE FALSE 3436.424092 3536.45634 3340.787918 3949.988088 3645.900352 3142.772823 3058.367687 4018.425374 3631.365845 3925.220368 0.875472909 0.900957401 0.851108372 1.006309893 0.92883966 0.800661499 0.779158213 1.023745165 0.925136809 1 11.93855794 -9.307993142 0.813590167 1.007171956 0.890856787 0.070406192 0.077557098 0.88686822 0.948132195 0.067870232 0.014311675 4.92E-10 9.307993142 -0.116315169 TTS(ph)PPEVSGYSYEK ddPTM_HeLa_Curcumin_4h_R1 2 TTSPPEVSGYSYEK 14 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 T(0.459)T(0.06)S(0.481)PPEVSGYSYEK;T(0.059)T(0.083)S(0.858)PPEVSGYSYEK ; 127.83 0.0011631 27375000 5447.5 4943.5 4745.6 5141.4 5507.8 6238.4 3857.8 3962.3 5298.6 5151.3 TRUE FALSE FALSE 5016.324627 5370.794112 4921.476111 5120.126249 5442.123082 4944.485519 3966.039485 5170.38703 4717.356836 5330.307292 0.941094829 1.007595588 0.923300636 0.960568682 1.020977363 0.927617349 0.744054567 0.969997928 0.885006544 1 12.38000299 -4.990890756 24.99896985 0.972538768 0.851728639 0.28919495 0.064131908 129.1742669 354493.2153 0.00724689 0.021697624 1.02E-05 4.990890756 -0.120810129 TTS(ph)PSS(ph)DTDLLDR ddPTM_HeLa_Curcumin_4h_R1 1 TTSPSSDTDLLDR 13 0 C9J9G2;Q96QT6-2;Q96QT6-5;Q96QT6-3;Q96QT6;K7ENU0;K7ERZ4;K7EJ43 C9J9G2 PHF12 PHD finger protein 12 2 0 T(0.003)T(0.022)S(0.974)PS(0.18)S(0.73)DT(0.091)DLLDR 115.06 0.0070755 15729000 1842.8 1679.8 1715.9 1915.8 1799.2 2331.7 1817.1 965 2217 2079.6 TRUE FALSE FALSE 1696.940435 1824.994427 1779.492763 1907.872927 1777.745715 1848.079136 1868.082936 1259.224058 1973.800647 2151.865945 0.788590218 0.848098568 0.826953355 0.886613282 0.826141479 0.858826332 0.868122357 0.585177743 0.917250747 1 11.07137249 -13.52287875 0.259695601 2.261810434 0.796908292 0.316529081 0.083857448 31.5583769 0.420757898 20.47227886 0.042530572 3.00E-14 13.52287875 -1.464902141 TTS(ph)PSSDTDLLDR ddPTM_HeLa_Curcumin_4h_R1 2 TTSPSSDTDLLDR 13 0 C9J9G2;Q96QT6-2;Q96QT6-5;Q96QT6-3;Q96QT6;K7ENU0;K7ERZ4;K7EJ43 C9J9G2 PHF12 PHD finger protein 12 1 0 T(0.02)T(0.048)S(0.931)PSSDTDLLDR;TT(0.009)S(0.991)PSSDTDLLDR ; 310.34 8.11E-89 129697000 9948.1 8955.3 8669.7 8282.5 8644.6 9661.9 6793.5 4207.7 9982.8 8286.5 TRUE FALSE FALSE 9160.697388 9729.356228 8991.006709 8248.22921 8541.518791 7657.913028 6984.107326 5490.60836 8887.711816 8574.455258 1.068370772 1.134690885 1.048580515 0.961953729 0.996158769 0.893107818 0.814524902 0.640344861 1.036533698 1 13.0658293 -4.256616263 0.774947033 1.041289311 0.400371039 0.913769307 0.040122822 0.604337516 0.255766587 0.007745314 0.335000443 5.54E-05 4.256616263 -0.640918272 TY(ph)KQIS(ph)TLAMHK ddPTM_HeLa_Curcumin_4h_R1 3 TYKQISTLAMHK 12 1 E7EN86;P52747-2;P52747-3;P52747 E7EN86 ZNF143 Zinc finger protein 143 2 0 T(0.251)Y(0.75)KQIS(0.784)T(0.216)LAMHK;T(0.382)Y(0.618)KQIS(0.909)T(0.091)LAMHK;T(0.404)Y(0.596)KQIS(0.881)T(0.119)LAMHK ;; 65.092 0.017384 54704000 12761.9 11514.1 11835.6 11854.5 10859.7 13890.7 10136.4 4116.46 13952.7 11618.8 TRUE FALSE FALSE 11751.78215 12509.3275 12274.23775 11805.44922 10730.20517 11009.61224 10420.8001 5371.549704 12422.12372 12022.55244 0.977478136 1.040488496 1.020934433 0.981942003 0.892506415 0.91574666 0.866771025 0.446789459 1.033235146 1 13.5534556 -4.036760599 1.336312484 0.9883419 1.25E-17 0.935593248 0.042355878 0.3663239 0.384749568 0.006026437 0.563890368 9.19E-05 4.036760599 -0.9883419 down TTSIS(ph)PALAR ddPTM_HeLa_Curcumin_4h_R1 2 TTSISPALAR 10 0 Q9UKE5-8;Q9UKE5-5;Q9UKE5-7;Q9UKE5-3;Q9UKE5-6;Q9UKE5-2;Q9UKE5-4;Q9UKE5 Q9UKE5-8 TNIK TRAF2 and NCK-interacting protein kinase 1 0 T(0.329)T(0.004)S(0.002)IS(0.665)PALAR;T(0.003)TS(0.006)IS(0.992)PALAR ; 121.29 0.0043436 131210000 9570.8 6853.3 7728.2 8451.9 8404.9 10488.1 7236.9 6240.4 9589.4 7634.4 TRUE FALSE FALSE 8813.261081 7445.668714 8014.61389 8416.928277 8304.677057 8312.749835 7439.947937 8143.069233 8537.466811 7899.694832 1.115645765 0.942526119 1.014547278 1.065475117 1.051265553 1.052287463 0.941801942 1.030808076 1.080733749 1 12.94758121 -4.787734257 24.79703961 1.045245409 0.986304971 0.15589175 0.049206232 250.6129947 236337.5198 0.007880675 0.023653311 1.63E-05 4.787734257 -0.058940438 TTSSANNPNLMYQDECDRR ddPTM_HeLa_Curcumin_4h_R1 1 TTSSANNPNLMYQDECDRR 19 1 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 0 112.91 0.00037954 28746000 2221.9 1909.7 1919.2 1992.8 2065.4 2171.9 1666.6 1307.1 2664.7 1787.7 FALSE FALSE TRUE 2046.03427 2074.765959 1990.32724 1984.554322 2040.771454 1721.423458 1713.360311 1705.628773 2372.389077 1849.822442 1.106070628 1.121602761 1.07595583 1.072835034 1.103225589 0.930588482 0.926229605 0.922049995 1.282495564 1 10.85317108 -5.249228626 23.68278686 1.063471587 0.926283346 0.484843923 0.076846879 185.3893017 359560.6373 0.006800988 0.017173744 5.63E-06 5.249228626 -0.137188241 TTSVSLTIGSS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 TTSVSLTIGSSSPK 14 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;H0Y952;Q8WX93-6;D6R9Z5;D6RBH5;D6RBB1 Q8WX93-3 PALLD Palladin 1 0 TTSVSLTIGS(0.001)S(0.5)S(0.5)PK 223.03 1.83E-14 50125000 3907.3 3352.9 3464.8 3510.9 3617.2 6669.2 5357.8 2103.3 3953.6 2961.6 TRUE FALSE FALSE 3598.033082 3642.709736 3593.208536 3496.372826 3574.067252 5285.932743 5508.125448 2744.586488 3519.899971 3064.51538 1.174095293 1.188673994 1.172520967 1.140921938 1.166274862 1.724883738 1.797388744 0.895602126 1.148599219 1 11.58144323 -5.401271705 6.282342157 1.106106856 1.503312173 0.292670396 0.231418005 0.181037533 8.590588582 0.031505824 0.070993758 3.97E-06 5.401271705 0.397205317 TTSVSLTIGSSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 TTSVSLTIGSSSPK 14 0 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;H0Y952;Q8WX93-6;D6R9Z5;D6RBH5;D6RBB1 Q8WX93-3 PALLD Palladin 1 0 TTSVSLTIGSS(0.06)S(0.94)PK;TTSVSLTIGS(0.002)S(0.385)S(0.613)PK ; 239.03 1.59E-28 47926500 4179.7 3722.2 3876.2 3971.5 3608.3 6125.2 4871.3 2748 4176.4 3789.3 TRUE FALSE FALSE 3848.872335 4043.930382 4019.855382 3955.066985 3565.273379 4854.764475 5007.975568 3585.85255 3718.259369 3920.977893 0.981610312 1.031357608 1.025217558 1.008694028 0.909281683 1.238151453 1.277226168 0.914530163 0.948298988 1 11.93699779 -5.260868374 24.99999742 0.993421297 1.156694951 0.356462965 0.095806281 37.34697655 1635084.37 0.012261314 0.029355904 5.48E-06 5.260868374 0.163273654 TASPSTS(ph)SIDSATDTR ddPTM_HeLa_Curcumin_4h_R1 2 TASPSTSSIDSATDTR 16 0 Q96P50-4;Q96P50-1;Q96P50 Q96P50-4 ACAP3 "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3" 1 0 TAS(0.001)PS(0.005)T(0.028)S(0.482)S(0.482)IDS(0.002)ATDTR;TASPST(0.053)S(0.473)S(0.473)IDSATDTR ; 168.93 0.00014732 17527500 4514 4614 4063.3 4356.8 4089.2 4422.6 2982.6 1673.03 4603.6 4727.8 TRUE FALSE FALSE 4156.712137 5012.8136 4213.889472 4338.772716 4040.438961 3505.302907 3066.283729 2183.129145 4098.596598 4892.090698 0.849680105 1.024677159 0.861367814 0.886895396 0.825912521 0.716524513 0.626783909 0.446256883 0.837800615 1 12.25623544 -4.035864469 0.553107559 0.939054258 2.17E-12 0.87298431 0.058332576 1.125490581 0.19552387 0.011773226 0.716013067 9.21E-05 4.035864469 -0.939054258 down TTTAAAVASTGPS(ph)SR ddPTM_HeLa_Curcumin_4h_R1 2 TTTAAAVASTGPSSR 15 0 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;P27816-4;B5MEG9;H7C4C5;H0Y2V1;F8W9U4 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 TTTAAAVASTGPS(0.949)S(0.051)R;TTTAAAVAS(0.093)T(0.017)GPS(0.755)S(0.134)R ; 220.52 3.63E-43 5088100 3142.6 2735.5 2706.7 2865.7 2846.9 3376.6 2854.2 2742 3641.3 3014.9 TRUE FALSE FALSE 2893.859894 2971.944431 2807.012683 2853.842493 2812.952577 2676.255098 2934.28117 3578.023177 3241.8585 3119.667551 0.927618038 0.952647801 0.899779428 0.914790582 0.901683443 0.857865479 0.940574956 1.14692451 1.039167939 1 11.60717658 -9.238408408 0.886880725 1.001470717 0.936033081 0.12601044 0.074646697 1.248770214 1.702031235 0.054510776 0.013767775 5.78E-10 9.238408408 -0.065437636 TTTAAAVASTGPSSR ddPTM_HeLa_Curcumin_4h_R1 2 TTTAAAVASTGPSSR 15 0 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;P27816-4;B5MEG9;H7C4C5;H0Y2V1;F8W9U4 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 0 0 ; ; 190.78 6.58E-12 5002300 2165.95 2202.9 2246.49 2106.2 2162.96 2637.4 2240.54 1661.42 2773.6 2263 FALSE FALSE TRUE 1994.512772 2393.30886 2329.746896 2097.485102 2137.168115 2090.37351 2303.403522 2167.97931 2469.343019 2341.639082 0.85175926 1.022065646 0.994921427 0.895733727 0.912680409 0.892696713 0.983671455 0.92583837 1.054536132 1 11.19330301 TTTAAAVASTGPSSRS(ph)PSTLLPK ddPTM_HeLa_Curcumin_4h_R1 2 TTTAAAVASTGPSSRSPSTLLPK 23 1 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;P27816-4;B5MEG9;H7C4C5;H0Y2V1;F8W9U4 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 T(0.001)T(0.001)T(0.007)AAAVAS(0.148)T(0.087)GPS(0.088)S(0.087)RS(0.441)PS(0.088)T(0.052)LLPK;TTTAAAVAS(0.002)T(0.005)GPS(0.006)S(0.028)RS(0.876)PS(0.041)T(0.041)LLPK ; 68.49 0.0008425 1959750000 3106.5 2575.44 2727.7 3187.9 2505.2 4123.7 2965.2 1737.73 4219.3 2887.8 TRUE FALSE FALSE 2860.617247 2798.049558 2828.790962 3174.709314 2475.327126 3268.398136 3048.395532 2267.555877 3756.453346 2988.150835 0.957320231 0.936381633 0.946669401 1.062432752 0.828380916 1.093786196 1.020161197 0.758849202 1.257116375 1 11.54503726 -4.444368508 0.007706257 1.886769425 2.80E-07 0.097607699 0.125161819 24874.179 32.15721107 3736.303329 4145.035407 3.59E-05 4.444368508 -1.886769145 TTTLSGTAPAAGVVPSR ddPTM_HeLa_Curcumin_4h_R1 2 TTTLSGTAPAAGVVPSR 17 0 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;P27816-4;B5MEG9;H7C4C5;H0Y2V1;F8W9U4 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 0 0 ; ; 164.22 0.00047222 6198600 3861.5 3391.1 2878.5 3286.2 3574.1 4690.5 3580.6 3334.6 4050.3 3360.7 FALSE FALSE TRUE 3555.8582 3684.211574 2985.179742 3272.602575 3531.481192 3717.637427 3681.061999 4351.304189 3605.992223 3477.484075 1.022537594 1.059447432 0.858430888 0.941083411 1.015527639 1.069059512 1.058541727 1.251279401 1.036954346 1 11.76382819 -3.596350412 1.047481065 0.999190834 1.913522297 0.649346893 0.056398689 2.970988768 0.951460459 0.008639526 4.253842476 0.000253308 3.596350412 0.914331463 TTTPPDS(ph)GVLFEGLGISTRPR ddPTM_HeLa_Curcumin_4h_R1 1 TTTPPDSGVLFEGLGISTRPR 21 1 Q9NS56-2;Q9NS56 Q9NS56-2 TOPORS E3 ubiquitin-protein ligase Topors 1 0 T(0.224)T(0.184)T(0.136)PPDS(0.457)GVLFEGLGISTRPR 123.42 6.45E-06 27880000 725.84 566.34 613.11 572.49 596.65 736.96 674.19 199.32 555.66 560.42 TRUE FALSE FALSE 668.3889981 615.291906 635.8323959 570.1211881 589.5353384 584.1061887 693.1059569 260.0917504 494.7054882 579.8945533 1.152604373 1.061041016 1.096462094 0.983146306 1.016625066 1.007262761 1.195227569 0.448515595 0.853095594 1 9.179646777 -4.254093675 24.99365493 1.066511841 0.448515303 0.778943993 0.093715482 228.6155701 777842.1718 0.010214663 0.140302577 5.57E-05 4.254093675 -0.617996538 REVS(ph)PAPAVAGQSK ddPTM_HeLa_Curcumin_4h_R1 1 REVSPAPAVAGQSK 14 1 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 0 REVS(1)PAPAVAGQSK 82.609 0.0078359 7972200 3852.3 3064.4 3001.3 3292.1 3297.5 3498.7 2513.7 1173.8 3682.1 3186.8 TRUE FALSE FALSE 3547.38639 3329.273081 3112.530818 3278.478162 3258.179466 2773.030182 2584.227657 1531.686216 3278.182842 3297.541063 1.075767162 1.009622934 0.943894483 0.994219056 0.988063349 0.840938787 0.783683238 0.464493447 0.994129498 1 11.68717491 -4.03523098 0.783301557 1.028432075 2.28E-15 0.943658451 0.040149964 0.5587454 0.193973824 0.007140844 0.54283699 9.22E-05 4.03523098 -1.028432075 down TTTTALKTTS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 TTTTALKTTSR 11 1 Q8WXI7 Q8WXI7 MUC16 Mucin-16 1 0 TTTTALKT(0.142)T(0.168)S(0.69)R 64.224 0.017946 6645100 2207.2 1753.2 1712.7 2182 1616.1 2610.1 1538.7 1994 2651.6 2048.7 TRUE FALSE FALSE 2032.497791 1904.738796 1776.174169 2172.971462 1596.829063 2068.735838 1581.871781 2601.961421 2360.726114 2119.892173 0.958774138 0.898507396 0.837860619 1.025038674 0.753259568 0.975868426 0.746203888 1.227402721 1.113606694 1 11.04977517 -7.631055294 1.863738412 0.985964215 0.913294499 0.07884198 0.138396465 0.685409888 4.912457906 0.023534776 0.024198963 2.34E-08 7.631055294 -0.072669716 TTVISAVGTIVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 TTVISAVGTIVKK 13 1 J3QQJ0;Q9UHR5-2;Q9UHR5 J3QQJ0 SAP30BP SAP30-binding protein 0 1 TTVISAVGTIVK(1)K 196.16 2.99E-57 0 724.6 683.23 754.69 598.71 440.47 1140.3 848.53 1167.1 909.84 799.04 FALSE TRUE FALSE 667.2471454 742.2853568 782.6594753 596.2326967 435.2176829 903.7889262 872.3374681 1522.943417 810.0328283 826.8065805 0.807017217 0.897773886 0.946605281 0.721127179 0.526383913 1.093108047 1.055068366 1.84195851 0.979712604 1 9.691406061 -4.074076989 1.658344105 0.875992599 2.571709173 0.792365947 0.149186173 0.582018548 1.046244059 0.022388173 1.816742194 8.43E-05 4.074076989 1.695716573 TTVTSSK(ac)ISQR ddPTM_HeLa_Curcumin_4h_R1 1 TTVTSSKISQR 11 1 E7EX82;Q8NDX5-2;Q8NDX5;Q8NDX5-7;Q8NDX5-3 E7EX82 PHC3 Polyhomeotic-like protein 3 0 1 TTVTSSK(1)ISQR 126.03 8.30E-08 0 529.82 446.69 459.7 474.2 370.11 525.38 567.63 291.82 309.44 328.6 FALSE TRUE FALSE 487.8841879 485.2998932 476.7368864 472.237886 365.69668 416.4102657 583.5561701 380.7945746 275.4952062 340.0188255 1.434874046 1.4272736 1.40208968 1.388858059 1.07551892 1.224668267 1.71624665 1.119922034 0.810235156 1 8.409470815 -9.316554554 0.997076143 0.996129969 1.357762402 0.457882456 0.184558081 0.461979639 0.80883841 0.12018867 0.030598734 4.82E-10 9.316554554 0.361632432 TTYDS(ph)AEEENKENLYAGK ddPTM_HeLa_Curcumin_4h_R1 2 TTYDSAEEENKENLYAGK 18 1 Q9HAW4-2;Q9HAW4-3;Q9HAW4;E7ESG2 Q9HAW4-2 CLSPN Claspin 1 0 T(0.002)T(0.001)Y(0.012)DS(0.985)AEEENKENLYAGK;T(0.042)T(0.015)Y(0.002)DS(0.937)AEEENKENLY(0.004)AGK ; 75.998 0.0039674 103065000 5095.2 3873.8 4109.6 4559.2 5069 4032.5 3296.6 1732.46 4467.4 3640.7 TRUE FALSE FALSE 4691.909544 4208.634011 4261.905391 4540.335238 5008.555486 3196.114044 3389.093724 2260.679079 3977.337397 3767.214054 1.245458707 1.117174111 1.1313149 1.205223588 1.329511786 0.848402559 0.899628658 0.600093078 1.055776853 1 11.87928229 -4.705169271 1.584320748 1.136485944 0.626768896 0.692058582 0.113630635 0.254490701 1.019504052 0.018674477 0.154590536 1.97E-05 4.705169271 -0.509717048 TTYLVLDEADR ddPTM_HeLa_Curcumin_4h_R1 2 TTYLVLDEADR 11 0 P17844-2;P17844;J3KTA4;J3KRZ1;J3QSF1 P17844-2 DDX5 Probable ATP-dependent RNA helicase DDX5 0 0 ; ; 182.46 0.0010568 44596000 7267.3 5837.2 5967 5691.5 5667.7 6937.7 5872.2 4961.5 6354 6327.3 FALSE FALSE TRUE 6692.085537 6341.741558 6188.142269 5667.950081 5600.116379 5498.742816 6036.958128 6474.23851 5656.982097 6547.173204 1.022133572 0.968622848 0.94516245 0.865709506 0.855348744 0.839865182 0.922070937 0.988860125 0.864034282 1 12.67665643 -6.717492583 2.0169646 1.009916671 0.89151472 0.077993833 0.06128825 0.154175728 1.284526088 0.007062539 0.010288703 1.92E-07 6.717492583 -0.118401951 TVACNRS(ph)NS(ph)QPRIMQVIAMS(ph)KQQGVLQS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 TVACNRSNSQPRIMQVIAMSKQQGVLQSSPK 31 3 W4VSQ3;Q7Z2D5-3;Q7Z2D5 W4VSQ3 LPPR4 Lipid phosphate phosphatase-related protein type 4 4 0 T(0.005)VACNRS(0.995)NS(0.993)QPRIMQVIAMS(0.72)KQQGVLQS(0.644)S(0.644)PK 45.862 0.0078437 12660000 2419.3 1858.9 1933.2 2122.8 1725.6 2186.4 2053 1824.2 2142.6 2004.6 TRUE FALSE FALSE 2227.809852 2019.575033 2004.846093 2114.016416 1705.023347 1732.915994 2110.601655 2380.390182 1907.562141 2074.259701 1.074026483 0.973636537 0.96653572 1.019166701 0.821991261 0.835438298 1.017520445 1.147585416 0.919635155 1 11.01838082 -7.114278723 5.982768856 1.03485243 0.960738448 0 0.096218149 0.39002418 18.07411501 0.015664793 0.019263439 7.69E-08 7.114278723 -0.074113982 TVADS(ph)DESYMEK ddPTM_HeLa_Curcumin_4h_R1 1 TVADSDESYMEK 12 0 Q9HAW4-2;Q9HAW4-3;Q9HAW4;E7ESG2 Q9HAW4-2 CLSPN Claspin 1 0 TVADS(0.853)DES(0.147)YMEK 133.16 0.0020646 7701500 3659.1 3118 3658.3 3037.5 3366.3 4267.4 3774.2 2100.5 4061.4 3924.4 TRUE FALSE FALSE 3369.478374 3387.506026 3793.879816 3024.93163 3326.159071 3382.293136 3880.093894 2740.93278 3615.874581 4060.772608 0.82976288 0.834202344 0.934275366 0.744915296 0.819095131 0.832918625 0.955506321 0.67497815 0.890440054 1 11.98753853 -9.599533186 0.445311049 1.068593567 0.824282767 0.193238429 0.083259154 1.806983547 0.388875535 0.209212793 0.020528212 2.51E-10 9.599533186 -0.2443108 TVAISDAAQLPHDYCTTPGGTLFSTT(ph)PGGTR ddPTM_HeLa_Curcumin_4h_R1 2 TVAISDAAQLPHDYCTTPGGTLFSTTPGGTR 31 0 Q13542 Q13542 EIF4EBP2 Eukaryotic translation initiation factor 4E-binding protein 2 1 0 TVAISDAAQLPHDYCTTPGGT(0.171)LFS(0.125)T(0.125)T(0.409)PGGT(0.171)R;TVAISDAAQLPHDY(0.001)CTT(0.008)PGGT(0.039)LFS(0.164)T(0.164)T(0.46)PGGT(0.164)R ; 109.97 7.36E-11 92599000 3347.4 2949.66 2904.1 2731.3 2859.2 3421.2 2461.9 2930.7 3110.5 2720.01 TRUE FALSE FALSE 3082.449758 3204.615467 3011.728501 2719.998604 2825.105907 2711.604555 2530.974288 3824.256939 2769.285932 2814.530145 1.095191595 1.13859696 1.070064396 0.96641303 1.003757559 0.963430632 0.899252862 1.358755011 0.983924772 1 11.45867838 TVANLLSGKS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 TVANLLSGKSPR 12 1 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;A0A2R8Y857;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 TVANLLSGKS(1)PR;TVANLLS(0.006)GKS(0.994)PR ; 175.01 0.0013453 2806400000 9977.8 8593.2 8741.8 9801.7 8455.6 12504.7 10095.3 5528.4 10934.5 9126.2 TRUE FALSE FALSE 9188.046601 9335.957917 9065.778798 9761.143163 8354.772493 9911.084263 10378.54695 7213.98371 9735.012707 9443.334771 0.972966312 0.98862935 0.960018788 1.033654255 0.884726921 1.049532237 1.099034102 0.763923326 1.030887175 1 13.2050807 -4.243363263 24.75363508 0.991279034 0.763923107 0.616459934 0.055783553 1683.041584 2304736.607 0.00699229 0.301170307 5.71E-05 4.243363263 -0.227355927 TVAQQHDEDGIEEEDDDDDEIDDDDTISDWNLRK ddPTM_HeLa_Curcumin_4h_R1 3 TVAQQHDEDGIEEEDDDDDEIDDDDTISDWNLRK 34 1 Q92973-2;Q92973;Q92973-3 Q92973-2 TNPO1 Transportin-1 0 0 ;; ;; 147.23 2.55E-18 255626000 7461.1 4908.6 5439.6 6651.6 5849.9 7746 5193 4659.4 8096.5 7085.5 FALSE FALSE TRUE 6870.546062 5332.877512 5641.196361 6624.077442 5780.143763 6139.392285 5338.701604 6080.029611 7208.334206 7331.720598 0.93709873 0.727370532 0.76942326 0.90348198 0.7883748 0.837374011 0.728164901 0.82927732 0.983170882 1 12.83993609 -7.418930015 4.665176449 0.973121388 0.799441663 0.720027351 0.050597271 0.089968993 3.092210879 0.009076358 0.010257407 3.81E-08 7.418930015 -0.173679725 TVAT(ph)PLNQVANPNSAIFGGAR ddPTM_HeLa_Curcumin_4h_R1 2 TVATPLNQVANPNSAIFGGAR 21 0 Q15056;Q15056-2 Q15056 EIF4H Eukaryotic translation initiation factor 4H 1 0 T(0.002)VAT(0.998)PLNQVANPNSAIFGGAR;T(0.006)VAT(0.993)PLNQVANPNS(0.001)AIFGGAR ; 118.16 3.80E-05 28874000 1916.18 1847.34 1813.24 1902.41 2247.81 4202.5 3708.1 1471.52 2019.83 1317.76 TRUE FALSE FALSE 1764.512331 2007.015838 1880.440269 1894.538331 2221.006334 3330.854128 3812.139306 1920.179674 1798.259702 1363.552062 1.29405571 1.471902609 1.379074787 1.389414005 1.628838675 2.442777376 2.795741661 1.408218819 1.318805312 1 10.41315407 -5.545928747 2.319121622 1.199509651 2.268919009 0.548712098 0.35662956 0.140970522 1.513784853 0.052033858 0.125180409 2.84E-06 5.545928747 1.069409357 TVAT(ph)PLNQVANPNSAIFGGARPR ddPTM_HeLa_Curcumin_4h_R1 2 TVATPLNQVANPNSAIFGGARPR 23 1 Q15056;Q15056-2 Q15056 EIF4H Eukaryotic translation initiation factor 4H 1 0 T(0.402)VAT(0.598)PLNQVANPNSAIFGGARPR;T(0.054)VAT(0.946)PLNQVANPNSAIFGGARPR ; 112.28 8.19E-06 150820000 2090.4 1494.93 2213.1 2241.48 2127.84 4513.3 3018.1 1537.64 2148.85 1677.82 TRUE FALSE FALSE 1924.942634 1624.145088 2295.119433 2232.20535 2102.466898 3577.190705 3102.779763 2006.459358 1913.126531 1736.12412 1.108758649 0.935500561 1.321978887 1.285740647 1.211011859 2.060446407 1.787187752 1.15571193 1.101952625 1 10.76165438 -5.835593971 1.303965902 1.053888238 1.655140949 0.464173552 0.247543256 0.255163715 0.865363359 0.038434026 0.096127448 1.46E-06 5.835593971 0.601252711 TVATPLNQVANPNSAIFGGARPR ddPTM_HeLa_Curcumin_4h_R1 2 TVATPLNQVANPNSAIFGGARPR 23 1 Q15056;Q15056-2 Q15056 EIF4H Eukaryotic translation initiation factor 4H 0 0 ; ; 218.88 6.28E-30 6433900 490.66 415.28 453.852 623.04 403.13 559.07 362.6 420.19 361.9 392.83 FALSE FALSE TRUE 451.8237433 451.1749527 470.6721544 620.4620256 398.322938 443.11258 372.7735801 548.3039967 322.2004754 406.4808133 1.111549988 1.109953872 1.157919732 1.526423893 0.979930479 1.090119301 0.917075463 1.348904988 0.792658509 1 8.667043445 -8.365807694 0.769479726 1.010898241 1.154263878 0.202104253 0.178581546 1.001142589 1.255544101 0.067698784 0.037087588 4.31E-09 8.365807694 0.143365637 TVAYTEQK ddPTM_HeLa_Curcumin_4h_R1 2 TVAYTEQK 8 0 P30101 P30101 PDIA3 Protein disulfide-isomerase A3 0 0 ; ; 112.41 0.0051628 5059800 4787.2 3243.3 4538.6 3887 4125.9 4729.6 3108.8 2406.1 3759 3846 FALSE FALSE TRUE 4408.288069 3523.6364 4706.804509 3870.916624 4076.701337 3748.627646 3196.024561 3139.708814 3346.647105 3979.648214 1.107707976 0.885414039 1.182718737 0.97267809 1.024387362 0.9419495 0.803092231 0.788941295 0.840940436 1 11.95842519 -4.913179715 1.52596782 1.044140168 0.768853109 0.35739039 0.098506114 0.221170365 0.898721947 0.010833075 0.063060925 1.22E-05 4.913179715 -0.275287059 TVCDAAEK(ac)GVR ddPTM_HeLa_Curcumin_4h_R1 2 TVCDAAEKGVR 11 1 O60664-4;O60664-3;O60664;K7ER39;K7EL96 O60664-4 PLIN3 Perilipin-3 0 1 ; TVCDAAEK(1)GVR;TVCDAAEK(1)GVR 174.98 2.22E-09 29422000 2297.9 1886.88 2044.9 1906.94 1732.1 2246.12 1724.39 1820.79 1967.61 1679.31 FALSE TRUE FALSE 2116.01879 2049.973499 2120.685793 1899.049588 1711.445839 1780.249393 1772.771742 2375.940489 1751.768106 1737.665898 1.217736271 1.179728222 1.220422059 1.092873832 0.984910759 1.024506147 1.020202874 1.367317211 1.008115604 1 10.76293501 -6.017444674 24.7295365 1.122015821 1.082081535 0.004437482 0.12164846 2727.760214 3866874.035 0.019729902 0.033189883 9.61E-07 6.017444674 -0.039934286 TVDLGIS(ph)DLEDDC ddPTM_HeLa_Curcumin_4h_R1 1 TVDLGISDLEDDC 13 0 F5H5U2;Q8NHQ9-2;Q8NHQ9 F5H5U2 DDX55 ATP-dependent RNA helicase DDX55 1 0 TVDLGIS(1)DLEDDC 154.66 0.00040381 2269000 2065.5 1662.8 1721.2 2252.9 1991.3 2242.3 1446.4 1354.8 2051.1 1956.6 TRUE FALSE FALSE 1902.013495 1806.525023 1784.989186 2243.578097 1967.555048 1777.221704 1486.982091 1767.872283 1826.099462 2024.591704 0.939455344 0.892291033 0.881653907 1.108163237 0.97182807 0.87781734 0.734460231 0.873199411 0.901959372 1 10.98341528 -5.060486669 3.809070916 0.967986595 0.803033451 0.427669114 0.07007226 0.136296242 3.915310935 0.009568081 0.027655766 8.70E-06 5.060486669 -0.164953145 TVDLK(ac)PDWGK ddPTM_HeLa_Curcumin_4h_R1 1 TVDLKPDWGK 10 1 P31948;P31948-2;P31948-3;F5H783;F5GXD8 P31948 STIP1 Stress-induced-phosphoprotein 1 0 1 TVDLK(1)PDWGK 105.17 0.0066968 2846100 1748.4 2575.1 2056.4 2170.6 4092.8 5183.1 3757.3 3172.1 4476.3 2170.5 FALSE TRUE FALSE 1610.012295 2797.68017 2132.611993 2161.618632 4043.996033 4108.066634 3862.719726 4139.258687 3985.261089 2245.924713 0.716859423 1.245669613 0.949547409 0.962462642 1.800592873 1.829120366 1.719879434 1.843008656 1.774441087 1 11.13309385 -5.773219888 6.013175838 0.906027663 1.798203671 0.492618436 0.30435949 0.037500678 4.801785624 0.023196569 0.044043148 1.69E-06 5.773219888 0.892176008 TVDSQGPTPVCT(ph)PTFLER ddPTM_HeLa_Curcumin_4h_R1 1 TVDSQGPTPVCTPTFLER 18 0 H7BZL0;Q9BYG3;C9J808 H7BZL0 NIFK MKI67 FHA domain-interacting nucleolar phosphoprotein 1 0 TVDSQGPT(0.026)PVCT(0.953)PT(0.021)FLER 146.67 0.00049797 10419000 1142.6 1180.4 806.71 1257.4 976.74 1283.6 780.69 1058.8 1065.6 846.45 TRUE FALSE FALSE 1052.162004 1282.428516 836.6073823 1252.197212 965.0930134 1017.366891 802.5940603 1381.623246 948.706346 875.8640745 1.201284577 1.464186686 0.95517947 1.429670709 1.101875327 1.161557964 0.916345451 1.577440251 1.083166183 1 9.774563185 -8.929898405 0.888945141 1.006693921 1.212222921 0.106890576 0.20465507 0.825624166 1.247301562 0.10068674 0.036763894 1.18E-09 8.929898405 0.205529 VGS(ph)LDNVGHLPAGGAVK ddPTM_HeLa_Curcumin_4h_R1 4 VGSLDNVGHLPAGGAVK 17 0 E7EVA0;P27816;P27816-6;P27816-2;P27816-5;P27816-4;H7C4C5;H0Y2V1;F8W9U4 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 VGS(1)LDNVGHLPAGGAVK;VGS(1)LDNVGHLPAGGAVK;VGS(1)LDNVGHLPAGGAVK;VGS(1)LDNVGHLPAGGAVK ;;; 202.5 1.45E-10 796785000 41015.7 32052 36677.3 39813.2 34039.6 36577.7 31033.4 11803.5 45014.3 33688.9 TRUE FALSE FALSE 37769.26407 34822.43206 38036.593 39648.46353 33633.7 28991.0727 31904.11368 15402.33281 40076.34391 34859.58677 1.083468497 0.998934161 1.091137232 1.137376177 0.964833583 0.831652793 0.915217782 0.441839225 1.149650573 1 15.08926785 -4.034722727 1.003580573 1.043246951 1.33E-14 0.835157709 0.080175938 0.761910104 0.439666813 0.011131903 0.948859868 9.23E-05 4.034722727 -1.043246951 down TVEDEDQDS(ph)EEEKDNDSYIK ddPTM_HeLa_Curcumin_4h_R1 2 TVEDEDQDSEEEKDNDSYIK 20 1 Q9Y5T5-2;Q9Y5T5;Q9Y5T5-4;Q9Y5T5-3 Q9Y5T5-2 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 0 TVEDEDQDS(0.998)EEEKDNDS(0.001)YIK;TVEDEDQDS(1)EEEKDNDSYIK ; 87.411 0.00069631 366750000 5279.3 4770.7 5565.8 5422.7 5579.9 5513.9 4656.4 4332.1 4673.9 4331.5 TRUE FALSE FALSE 4861.437834 5183.05805 5772.073444 5400.262304 5513.363337 4370.254986 4787.046052 5652.937347 4161.184864 4482.019303 1.08465348 1.156411363 1.287828779 1.204872612 1.230107004 0.975063847 1.068055653 1.261247881 0.928417435 1 12.12993315 -7.726239188 1.37047335 1.024764316 1.164616265 0.396292282 0.093505711 0.34382742 1.340705902 0.020673154 0.020014417 1.88E-08 7.726239188 0.139851949 TVEDEDQDS(ph)EEEKDNDSYIKER ddPTM_HeLa_Curcumin_4h_R1 2 TVEDEDQDSEEEKDNDSYIKER 22 2 Q9Y5T5-2;Q9Y5T5;Q9Y5T5-4;Q9Y5T5-3 Q9Y5T5-2 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 0 TVEDEDQDS(0.999)EEEKDNDSYIKER;T(0.007)VEDEDQDS(0.81)EEEKDNDS(0.047)Y(0.136)IKER ; 70.295 0.00069741 217170000 7870.5 6432.7 6544.2 7267.3 6520 8087.7 6780.2 5312.2 9135.3 7907.4 TRUE FALSE FALSE 7247.54162 6988.713924 6786.733809 7237.229838 6442.253258 6410.219853 6970.434164 6931.865326 8133.180445 8182.181561 0.885771303 0.854138211 0.829452849 0.88451103 0.787351541 0.783436521 0.851904118 0.847190358 0.994011241 1 12.99826984 -8.408236125 0.417790682 1.017453404 0.818488592 0.842431396 0.028005017 0.359478388 0.133375559 0.030479224 0.011746166 3.91E-09 8.408236125 -0.198964811 TVEDLKNNESQWKDS(ph)PLATR ddPTM_HeLa_Curcumin_4h_R1 1 TVEDLKNNESQWKDSPLATR 20 2 O95155-2;O95155;O95155-4;O95155-3;K7EP75 O95155-2 UBE4B Ubiquitin conjugation factor E4 B 1 0 TVEDLKNNES(0.012)QWKDS(0.965)PLAT(0.023)R 59.561 0.0051213 79360000 1610.4 1568.4 1296.7 1655.5 1517.4 2160 1361.2 1320.3 1917.9 1850.7 TRUE FALSE FALSE 1482.935141 1703.965507 1344.756843 1648.64998 1499.305996 1711.991652 1399.391609 1722.853392 1707.511168 1915.011687 0.774373938 0.88979379 0.702218609 0.860908573 0.782922635 0.893984963 0.730748338 0.899656855 0.891645299 1 10.90313748 -9.341867209 0.905908541 1.008002464 0.812498103 0.287362218 0.073628875 0.362114987 0.496515065 0.049504957 0.01105071 4.55E-10 9.341867209 -0.195504362 TVEIVHIDIADR ddPTM_HeLa_Curcumin_4h_R1 2 TVEIVHIDIADR 12 0 A0A0A0MSW4;P48739;P48739-2;P48739-3;B3KYB6;B3KYB7 A0A0A0MSW4 PITPNB Phosphatidylinositol transfer protein beta isoform 0 0 ; ; 98.942 0.0078955 8555600 8083.5 6706.1 6922.2 6808.4 6686.6 9069.8 6173 6305.7 8891 8654.3 FALSE FALSE TRUE 7443.682445 7285.745402 7178.742821 6780.228645 6606.866662 7188.621242 6346.197766 8228.278902 7915.679544 8955.036281 0.83122862 0.813591947 0.801643075 0.757141393 0.737782233 0.802746188 0.708673596 0.918843726 0.883936066 1 13.12848356 -8.718282696 0.502336966 1.018679675 0.778280647 0.427222258 0.063254675 0.436601393 0.202908612 0.049058333 0.014499619 1.91E-09 8.718282696 -0.240399028 TVESLEETLKK ddPTM_HeLa_Curcumin_4h_R1 1 TVESLEETLKK 11 1 F2Z3J9;Q14914-2;Q14914 F2Z3J9 PTGR1 Prostaglandin reductase 1 0 0 101.35 0.0026143 2317300 2216.4 2076.3 2180.9 1770.6 1901 1987.9 1938.8 1473.7 1998 2167 FALSE FALSE TRUE 2040.969601 2255.76612 2261.726073 1763.273726 1878.331817 1575.587132 1993.19751 1923.024346 1778.824399 2242.303089 0.910211296 1.006004109 1.008662069 0.786367256 0.837679717 0.702664657 0.888906375 0.857611246 0.79330239 1 11.13076558 -6.257547145 24.99457908 0.964404682 0.813829913 0.40307019 0.076421976 172.9746408 1110781.391 0.008906125 0.014411004 5.53E-07 6.257547145 -0.150574769 TVFPGAVPVLPAS(ph)PPPK ddPTM_HeLa_Curcumin_4h_R1 2 TVFPGAVPVLPASPPPK 17 0 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 0 TVFPGAVPVLPAS(1)PPPK;TVFPGAVPVLPAS(1)PPPK ; 134.37 0.00034882 58531000 7992.4 7048 8504.6 7397.1 8193.8 8710.2 8287 8412.5 7162.7 6209.6 TRUE FALSE FALSE 7359.793106 7657.197715 8819.787957 7366.49276 8096.094287 6903.606336 8519.510917 10977.43252 6376.96973 6425.383138 1.145424786 1.191710681 1.372647789 1.146467472 1.260017358 1.074427188 1.32591485 1.70844793 0.992465289 1 12.64956677 -1 0.724678398 1.106831433 88.97574962 0.676922614 0.114783332 139.9897189 0.628837721 0.020645394 20033.7924 0.1 1 87.86891819 TVFPGAVPVLPAS(ph)PPPKDSLR ddPTM_HeLa_Curcumin_4h_R1 2 TVFPGAVPVLPASPPPKDSLR 21 1 M0R165;Q9UBC2-4;Q9UBC2-3;Q9UBC2;Q9UBC2-2;M0R2S2 M0R165 EPS15L1 Epidermal growth factor receptor substrate 15-like 1 1 0 TVFPGAVPVLPAS(0.999)PPPKDS(0.001)LR;TVFPGAVPVLPAS(0.999)PPPKDS(0.001)LR ; 149.74 4.42E-06 1161080000 9641.9 7688.3 8370.4 9265.7 8516.2 11883.3 8680.8 10329.4 9773.4 8646.7 TRUE FALSE FALSE 8878.733441 8352.842394 8680.614387 9227.360988 8414.649877 9418.569628 8924.359885 13478.78651 8701.282472 8947.172181 0.992350797 0.933573449 0.970207593 1.031315906 0.940481496 1.052686752 0.997450334 1.506485651 0.972517606 1 13.12721606 -4.261150154 7.379574887 0.992591894 1.512569342 0.951728399 0.035028144 0.013977265 6.849928271 0.004428688 0.035851154 5.48E-05 4.261150154 0.519977448 TVFS(ph)PTLPAAR ddPTM_HeLa_Curcumin_4h_R1 1 TVFSPTLPAAR 11 0 Q7Z2W4-2;Q7Z2W4;C9J6P4;Q7Z2W4-3 Q7Z2W4-2 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 0 T(0.142)VFS(0.854)PT(0.004)LPAAR 136.81 0.0018258 185830000 2549.7 2181 2175.4 2551.4 2076 2354.8 2030.2 1312 2607 1899.5 TRUE FALSE FALSE 2347.888555 2369.515922 2256.022238 2540.842983 2051.245056 1866.387936 2087.161948 1712.02276 2321.018622 1965.507484 1.194545721 1.205549173 1.147806486 1.292716005 1.043621087 0.949570506 1.061894684 0.871033448 1.180874986 1 10.94068614 -5.525374353 24.99774184 1.122594615 0.975215162 0.491263306 0.088930425 75.01219926 751374.4079 0.01559722 0.031341954 2.98E-06 5.525374353 -0.147379453 TVGDISR ddPTM_HeLa_Curcumin_4h_R1 1 TVGDISR 7 0 Q6ZN68-3;Q6ZN68-2;Q6ZN68 Q6ZN68-3 DPY19L2P2 Putative C-mannosyltransferase DPY19L2P2 0 0 115.46 0.0085803 0 3779.7 2894.4 3027.7 3291 3107.5 3810.9 2873.5 1881.7 3435.5 2984.8 FALSE FALSE TRUE 3480.532757 3144.579039 3139.909225 3277.382714 3070.445092 3020.476382 2954.122676 2455.421668 3058.634245 3088.521578 1.126925187 1.018150257 1.016638267 1.061149366 0.994147204 0.97796836 0.95648439 0.795015222 0.990323094 1 11.59270069 -3.191425328 0.636453889 1.055393416 2.15E-22 0.732005087 0.041602384 4.3631026 0.445272932 0.008786049 4.611544552 0.000643539 3.191425328 -1.055393416 TVGQLYK ddPTM_HeLa_Curcumin_4h_R1 2 TVGQLYK 7 0 P35579;P35579-2;Q7Z406-5;Q7Z406-4;M0QY43;P35580;P35580-5;P35580-2;P35580-3;P35580-4;P35749-4;P35749-3;P35749;P35749-2;Q7Z406;Q7Z406-6;Q7Z406-2 P35579;P35580;P35749-4;Q7Z406 MYH9;MYH14;MYH10;MYH11 Myosin-9;Myosin-14;Myosin-10;Myosin-11 0 0 ; ; 104.21 0.0177 8615500 4143.6 3315.6 3284.43 3541.8 4097.5 4547.7 3260 4110.8 4086.7 3974.4 FALSE FALSE TRUE 3815.629688 3602.18569 3406.153865 3527.14497 4048.639989 3604.455757 3351.466826 5364.163996 3638.399234 4112.510104 0.92781041 0.875909262 0.828242066 0.857662323 0.984469311 0.876461253 0.814944338 1.304352782 0.884714965 1 12.00580351 -4.250210447 24.74959615 0.930606622 1.304353033 0.756314936 0.067030715 654.2254498 1441942.205 0.010641313 0.215508295 5.62E-05 4.250210447 0.373746411 TVGSEPDFFS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 TVGSEPDFFSK 11 0 H0YLU3 H0YLU3 MAN2A2 1 0 TVGSEPDFFS(1)K 91.853 0.016062 22970000 1411.5 1417.7 1251 1410.2 1549.3 1524.4 1233.1 1206.1 1041.3 1096.1 TRUE FALSE FALSE 1299.778286 1540.239671 1297.36316 1404.364966 1530.825609 1208.222256 1267.697467 1573.834338 927.0719952 1134.189393 1.145997567 1.358009235 1.143868183 1.23821028 1.34970898 1.06527381 1.117712328 1.387629215 0.817387291 1 10.14744585 -8.248947893 0.833941776 1.017803742 1.226869168 0.476916535 0.122583857 0.385666743 0.572109173 0.036783246 0.023089214 5.64E-09 8.248947893 0.209065426 TVGVEPAADGK ddPTM_HeLa_Curcumin_4h_R1 2 TVGVEPAADGK 11 0 H0YMF4;H0YKD8;P46779-4;P46779-5;P46779;P46779-2;P46779-3;H0YLP6 H0YMF4 RPL28 60S ribosomal protein L28 0 0 ; ; 146.11 1.54E-05 25773000 9665.6 9038.1 9021.3 10023.7 9374.4 9051.3 7262 7594.3 9635.7 9063.2 FALSE FALSE TRUE 8900.557561 9819.313091 9355.637314 9982.224585 9262.616403 7173.958351 7465.752175 9909.76711 8578.687817 9378.145525 0.94907437 1.04704209 0.997599929 1.064413488 0.987681027 0.764965561 0.796079796 1.056687283 0.914753113 1 13.19508695 -5.350131158 11.41094975 0.990101964 0.864972371 0.312765694 0.082331753 0.569414915 71.34810173 0.010932946 0.024454671 4.47E-06 5.350131158 -0.125129594 TVHPNS(ph)PGIPYR ddPTM_HeLa_Curcumin_4h_R1 1 TVHPNSPGIPYR 12 0 J3KPH8;Q8WUI4-3;Q8WUI4-4;Q8WUI4;Q8WUI4-7;Q8WUI4-6;Q8WUI4-5;Q8WUI4-8;C9J102;C9JNI4;F8VWY3 J3KPH8 HDAC7 Histone deacetylase;Histone deacetylase 7 1 0 TVHPNS(1)PGIPYR 130.66 0.0011277 17515000 4807.6 3388.3 4219.5 4311.8 4565.2 5609.7 4795.3 4097.4 4516.6 4047.8 TRUE FALSE FALSE 4427.073387 3681.169554 4375.878382 4293.958914 4510.762972 4446.184986 4929.843212 5346.678398 4021.14028 4188.460749 1.056969052 0.878883622 1.044746183 1.025187813 1.07695004 1.061531969 1.177005948 1.276525845 0.960052039 1 12.03220444 -4.229216535 0.885265727 1.016653384 1.443754939 0.751547711 0.051927937 0.867500792 0.481956822 0.007864825 0.363027384 5.90E-05 4.229216535 0.427101555 TVIESS(ph)PESPVTITEPYR ddPTM_HeLa_Curcumin_4h_R1 1 TVIESSPESPVTITEPYR 18 0 Q8TEQ6 Q8TEQ6 GEMIN5 Gem-associated protein 5 1 0 TVIES(0.021)S(0.667)PES(0.306)PVT(0.005)IT(0.001)EPYR 174.18 4.17E-06 9026400 1137.9 1117.4 986.81 1036.4 1279.8 1609.4 811.43 2147.7 1100.3 1175.7 TRUE FALSE FALSE 1047.834014 1213.983077 1023.382047 1032.111651 1264.539221 1275.592298 834.1965419 2802.523843 979.5998428 1216.555487 0.861312143 0.997885497 0.841212799 0.848388472 1.039442289 1.048527841 0.685703653 2.303654763 0.805224137 1 10.24858641 -4.255261103 24.98691388 0.927709282 2.303655374 0.931717828 0.113570913 113.4120855 458661.6441 0.014245081 0.176648092 5.56E-05 4.255261103 1.375946093 TVIIEQS(ph)WGSPK ddPTM_HeLa_Curcumin_4h_R1 2 TVIIEQSWGSPK 12 0 P10809;E7EXB4;E7ESH4;P10809-2;C9JL25;C9JL19;C9JCQ4 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 1 0 TVIIEQS(0.984)WGS(0.016)PK;TVIIEQS(0.9)WGS(0.1)PK ; 167.22 0.00012441 711860000 6264.3 5393.4 5815.9 7102.2 7107.8 9657.7 6385.5 5712.3 7097.7 5156.8 TRUE FALSE FALSE 5768.474045 5859.581463 6031.44237 7072.812978 7023.044127 7654.584155 6564.659944 7453.953974 6319.100068 5335.998416 1.08104868 1.098122789 1.130330615 1.325490082 1.316163083 1.434517696 1.230258975 1.396918326 1.184239495 1 12.38154252 -6.440351054 1.296181649 1.037156424 1.350480923 0.724576217 0.072278658 0.106381157 0.354924062 0.009591344 0.016873605 3.63E-07 6.440351054 0.313324499 TVIIEQSWGSPK ddPTM_HeLa_Curcumin_4h_R1 2 TVIIEQSWGSPK 12 0 P10809;E7EXB4;E7ESH4;P10809-2;C9JL25;C9JL19;C9JCQ4 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 ; ; 252.97 4.83E-63 4459100 5299.4 4365 4625 5170 5262.2 8035.2 4948.8 5256 6156.1 4281.2 FALSE FALSE TRUE 4879.946898 4742.29115 4796.406569 5148.60791 5199.451702 6368.608945 5087.650009 6858.530204 5480.791232 4429.971381 1.101575265 1.070501532 1.082717281 1.162221483 1.173698711 1.43761853 1.148461146 1.548210951 1.237206916 1 12.11308166 -1.000000004 0.258318954 1.014750973 4.037882927 0.521553931 0.112375427 17.6093414 0.221452681 0.042111109 23.67595435 0.099999999 1.000000004 3.023131954 TVIRLPS(ph)GSGAAS(ph)PTGSAVDIR ddPTM_HeLa_Curcumin_4h_R1 1 TVIRLPSGSGAASPTGSAVDIR 22 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 T(0.05)VIRLPS(0.507)GS(0.537)GAAS(0.725)PT(0.173)GS(0.008)AVDIR 75.911 0.0055521 10936000 1016.1 838.83 722.09 1122.3 533.05 1189.5 700.6 743.22 1907.2 1349.6 TRUE FALSE FALSE 935.6746128 911.3347274 748.8512906 1117.65622 526.6937269 942.7842916 720.2569504 969.8243566 1697.984932 1396.4985 0.670014764 0.65258554 0.536234941 0.800327548 0.377153092 0.675105839 0.515759201 0.694468599 1.215887401 1 10.44759831 -8.972171364 0.44672157 1.074857339 0.583919699 0.685521347 0.1294798 0.668854551 0.210230479 0.148198864 0.031466138 1.07E-09 8.972171364 -0.49093764 GSSDGRGSDS(ph)ESDLPHR ddPTM_HeLa_Curcumin_4h_R1 1 GSSDGRGSDSESDLPHR 17 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46;D6RJ93;Q6NVB9;D6R8Y0;Q9UPQ0-7 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 GSSDGRGS(0.114)DS(0.801)ES(0.085)DLPHR 94.911 0.0013737 19460000 2572 2231.4 2149.7 2427.7 2890 4000.9 2879.4 3592.8 3069.5 2136.9 TRUE FALSE FALSE 2368.423486 2424.272273 2229.369773 2417.654821 2855.538638 3171.068241 2960.188214 4688.228181 2732.78353 2211.157116 1.071124014 1.096381734 1.008236709 1.093388979 1.291422765 1.434121627 1.338750735 2.120260088 1.235906535 1 11.11058583 -1 0.535207056 1.033611163 42.25010556 0.870386486 0.113763749 20.26688142 0.176802758 0.016766378 959.1922033 0.1 1 41.2164944 up TVIRLPS(ph)GSGAASPTGSAVDIR ddPTM_HeLa_Curcumin_4h_R1 2 TVIRLPSGSGAASPTGSAVDIR 22 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 TVIRLPS(0.995)GS(0.004)GAAS(0.001)PTGSAVDIR;TVIRLPS(0.853)GS(0.046)GAAS(0.026)PT(0.009)GS(0.066)AVDIR ; 167.53 1.29E-07 64139000 1146.92 470.99 680.8 1014.38 433.26 983.47 825.63 10026.2 1113.29 975.55 TRUE FALSE FALSE 1056.140072 511.7002769 706.0310469 1010.182764 428.0936575 779.487236 848.7949557 13083.14223 991.1648723 1009.45029 1.046252681 0.506909832 0.699421313 1.000725617 0.424085923 0.772189818 0.840848692 12.96066023 0.981885767 1 9.979354152 -4.261270482 24.99949156 0.899473625 12.96066379 0.996336538 0.221009628 0.608349632 89969.93889 0.034441992 0.266880678 5.48E-05 4.261270482 12.06119017 TVIRLPSGSGAAS(ph)PTGSAVDIR ddPTM_HeLa_Curcumin_4h_R1 1 TVIRLPSGSGAASPTGSAVDIR 22 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 TVIRLPS(0.174)GS(0.054)GAAS(0.765)PT(0.003)GS(0.003)AVDIR 137.73 0.00026435 55767000 3888.7 3064.1 2799.6 3748.7 2401.2 4198.7 2468.4 1650.4 5516.8 3982.2 TRUE FALSE FALSE 3580.905292 3328.947151 2903.355639 3733.188873 2372.567258 3327.842291 2537.656661 2153.599362 4911.620842 4120.581154 0.869029187 0.807882924 0.704598582 0.905986009 0.575784621 0.807614792 0.615849213 0.522644569 1.191972845 1 12.00863211 -3.591015455 0.14746665 1.08639523 1.49E-14 0.702078731 0.106396338 11.32314624 0.227836966 0.235605858 2.41760093 0.000256439 3.591015455 -1.08639523 TVIRLPSGSGAASPT(ph)GSAVDIR ddPTM_HeLa_Curcumin_4h_R1 1 TVIRLPSGSGAASPTGSAVDIR 22 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 TVIRLPSGSGAAS(0.209)PT(0.424)GS(0.367)AVDIR 97.085 0.00014535 179700000 2145.4 1190.7 1024.7 1252.6 682.35 1577 840.78 1021.1 2949.1 2013.2 TRUE FALSE FALSE 1975.589326 1293.618802 1062.676283 1247.417073 674.2134219 1249.912424 864.370024 1332.428689 2625.591108 2083.15855 0.94836244 0.620989124 0.510127414 0.598810433 0.323649595 0.600008302 0.414932423 0.639619432 1.260389474 1 11.02455693 -7.186482834 2.462214963 0.980464413 0.508582952 0.792738148 0.125019331 0.06662663 0.776088578 0.014100379 0.017185616 6.51E-08 7.186482834 -0.471881461 TVKEPEGPPPS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 2 TVKEPEGPPPSPGK 14 1 P58012 P58012 FOXL2 Forkhead box protein L2 1 0 TVKEPEGPPPS(1)PGK;TVKEPEGPPPS(1)PGK ; 108.17 0.0014206 26508000 12213.1 11282.3 11473.9 11522.4 13223.5 13308.2 10028.5 5646.7 12813.8 11749.8 TRUE FALSE FALSE 11246.42025 12257.49174 11899.13283 11474.72336 13065.8184 10547.92931 10309.87272 7368.352836 11408.1582 12158.10468 0.925014264 1.008174552 0.978699653 0.943792118 1.074659147 0.86756362 0.847983546 0.60604453 0.938317156 1 13.56963072 -4.172820211 1.301502524 0.97209654 0.395193926 0.845062762 0.048041246 0.457763378 0.570396022 0.007069912 0.368652155 6.72E-05 4.172820211 -0.576902614 TVKQEQINTEPLEDTVLS(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 1 TVKQEQINTEPLEDTVLSPTK 21 1 O15446;O15446-2 O15446 CD3EAP DNA-directed RNA polymerase I subunit RPA34 1 0 TVKQEQINTEPLEDT(0.013)VLS(0.854)PT(0.133)K 149.3 5.09E-06 87678000 4865.3 3077.5 2643.1 3749.4 2141.4 4689.1 2764.3 1942.6 6356.5 4476.5 TRUE FALSE FALSE 4480.206371 3343.505387 2741.055611 3733.885976 2115.865204 3716.527803 2841.858818 2534.889797 5659.207853 4632.058042 0.967217235 0.721818543 0.591757613 0.806096543 0.456787282 0.802349144 0.613519691 0.547249144 1.221748044 1 12.17743762 -7.19719744 2.994027064 0.986870122 0.642352447 0.69234079 0.124577151 0.09298822 1.626053584 0.015700591 0.01907525 6.35E-08 7.19719744 -0.344517675 TVLCGTCGQPADK ddPTM_HeLa_Curcumin_4h_R1 2 TVLCGTCGQPADK 13 0 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5 P02545 LMNA Prelamin-A/C;Lamin-A/C 0 0 ; ; 167.84 8.49E-06 7428700 3114.5 2888.7 2863.2 3150.8 2935.6 3231.6 2698.4 2235.54 3217 3097 FALSE FALSE TRUE 2867.984039 3138.386356 2969.312711 3137.762824 2900.594887 2561.329732 2774.109842 2917.145855 2864.103149 3204.620519 0.894952779 0.979331667 0.926572333 0.979137095 0.905128975 0.799261478 0.865659389 0.910293695 0.893741749 1 11.64593781 -5.523532291 7.234078739 0.951178439 0.857844554 0.467123169 0.041559553 0.087317464 29.54972342 0.006705381 0.014007971 3.00E-06 5.523532291 -0.093333885 TVLEGSTAST(ph)SPADHSALPNQSLTVR ddPTM_HeLa_Curcumin_4h_R1 1 TVLEGSTASTSPADHSALPNQSLTVR 26 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 TVLEGST(0.001)AS(0.167)T(0.697)S(0.134)PADHSALPNQSLTVR 115.66 1.16E-08 30758000 1391.1 950.1 1088.5 1166.3 1222.5 1790 1182.7 1519.2 1463.3 1042.8 TRUE FALSE FALSE 1280.992967 1032.22241 1128.840768 1161.47416 1207.922486 1418.733823 1215.883379 1982.397086 1302.779651 1079.037222 1.187162908 0.956614275 1.04615554 1.076398604 1.119444687 1.314814534 1.126822461 1.837190641 1.207353763 1 10.07552892 -1.674102956 1.044941481 1.081870715 200 0.812617609 0.103148285 132.2801257 0.686266907 0.015431481 62386.04817 0.02117859 1.674102956 198.9181293 QLPLEPES(ph)PSGQVGPRPAPPQEES(ph)PSSEAK ddPTM_HeLa_Curcumin_4h_R1 1 QLPLEPESPSGQVGPRPAPPQEESPSSEAK 30 1 Q3KQU3-4;Q3KQU3;Q3KQU3-2;C9JIR3;E9PLH3 Q3KQU3-4 MAP7D1 MAP7 domain-containing protein 1 2 0 QLPLEPES(0.584)PS(0.425)GQVGPRPAPPQEES(0.921)PS(0.049)S(0.021)EAK 59.011 0.0015135 20656000 2000.1 1374.8 1778.1 1755.8 1958.4 3059.8 2086.1 2188.2 1968 1354.7 TRUE FALSE FALSE 1841.789975 1493.631586 1843.99795 1748.534965 1935.047359 2425.162989 2144.630352 2855.372107 1752.115324 1401.775724 1.313897753 1.065528216 1.315472881 1.247371412 1.380425788 1.730064908 1.529938288 2.036967867 1.249925572 1 10.45303983 -1 0.273559029 1.083025629 7.529285311 0.810816667 0.127737149 14.23186397 0.180839767 0.058627871 44.0826013 0.1 1 6.446259683 up TVLPTVPES(ph)PEEEVKASQLSVQQNK ddPTM_HeLa_Curcumin_4h_R1 1 TVLPTVPESPEEEVKASQLSVQQNK 25 1 O75152;E9PBY7;E9PQ61;A0A1W2PPR9 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 0 TVLPTVPES(0.966)PEEEVKAS(0.031)QLS(0.002)VQQNK 77.53 0.0001041 29074000 2827.6 1823.7 2210.3 2135.4 1880.2 3448.9 2482.5 4674.5 3660.8 2796.1 TRUE FALSE FALSE 2603.792476 1981.332502 2292.215662 2126.564281 1857.779843 2733.559263 2552.152269 6099.733531 3259.219399 2893.264267 0.899949758 0.684808686 0.792259348 0.7350052 0.642105135 0.9448011 0.882101334 2.108253159 1.126485208 1 11.49848239 -4.26138167 23.56902021 0.884021941 2.108253709 0.87254323 0.143187592 0.535608752 217435.1931 0.020074355 0.154621883 5.48E-05 4.26138167 1.224231768 TVMDGGLES(ph)DGPNMTENGLEDESRPQR ddPTM_HeLa_Curcumin_4h_R1 2 TVMDGGLESDGPNMTENGLEDESRPQR 27 1 P51116 P51116 FXR2 Fragile X mental retardation syndrome-related protein 2 1 0 T(0.005)VMDGGLES(0.782)DGPNMT(0.213)ENGLEDESRPQR;TVMDGGLES(0.998)DGPNMT(0.002)ENGLEDESRPQR ; 78.755 2.85E-05 21321300 2393.6 2495.3 2360.26 2347.92 2879.7 2580 2401.6 2028.25 2241.75 1934.69 TRUE FALSE FALSE 2204.144034 2710.982613 2447.733312 2338.204929 2845.361458 2044.878917 2468.982432 2646.654088 1995.835634 2001.920333 1.101014859 1.354191057 1.222692667 1.167981008 1.421316029 1.021458688 1.233307036 1.322057648 0.996960568 1 10.96716885 -7.501618365 3.534675535 1.041006713 1.2422781 0.472710512 0.105397578 0.154202239 3.918139771 0.018298237 0.020036956 3.15E-08 7.501618365 0.201271387 TVPEELVKPEELSK ddPTM_HeLa_Curcumin_4h_R1 2 TVPEELVKPEELSK 14 1 Q9UMS4;H0YGF3;F5GY56 Q9UMS4 PRPF19 Pre-mRNA-processing factor 19 0 0 ; ; 105.95 0.0012442 3585800 2691.76 2195.64 2868.23 2495.58 2371.34 3545.51 2634.18 2302.03 3362.36 2881.39 FALSE FALSE TRUE 2478.704356 2385.421338 2974.529127 2485.253951 2343.063319 2810.13126 2708.088001 3003.90835 2993.51752 2981.518088 0.831356471 0.800069383 0.997655905 0.833553203 0.78586252 0.942516925 0.908291656 1.007509685 1.004024605 1 11.54183137 -9.470637625 1.231311468 0.999478096 0.880690817 0.267792652 0.073958952 0.507948958 1.38729444 0.050224668 0.012587575 3.38E-10 9.470637625 -0.118787279 TVPIDDS(ph)SETLEPVCR ddPTM_HeLa_Curcumin_4h_R1 1 TVPIDDSSETLEPVCR 16 0 Q9Y5T5-2;Q9Y5T5;H9KVB6;Q9Y5T5-5 Q9Y5T5-2 USP16 Ubiquitin carboxyl-terminal hydrolase 16 1 0 TVPIDDS(0.465)S(0.465)ET(0.07)LEPVCR 115.82 0.001198 3387900 851.5 557.69 693.38 733.18 646.73 877.37 750.65 539.69 751.55 648.48 TRUE FALSE FALSE 784.1028765 605.8942386 719.0772728 730.1462954 639.0181671 695.393572 771.7112187 704.2389966 669.1068453 671.0146317 1.168533202 0.90295235 1.071626815 1.088122763 0.952316294 1.036331459 1.150066157 1.049513622 0.997156863 1 9.390200415 DSLS(ph)PVLHPSDLILTR ddPTM_HeLa_Curcumin_4h_R1 2 DSLSPVLHPSDLILTR 16 0 Q9HCN4-3;Q9HCN4-2;Q9HCN4-4;Q9HCN4;Q9HCN4-5 Q9HCN4-3 GPN1 GPN-loop GTPase 1 1 0 DS(0.005)LS(0.995)PVLHPSDLILTR;DS(0.084)LS(0.916)PVLHPSDLILTR ; 125.59 0.00028008 32939000 4005.7 3980.8 3612.8 3611 6263.3 12013.7 5812.5 12262.3 4887.2 3704.6 TRUE FALSE FALSE 3688.644618 4324.882614 3746.693546 3596.058639 6188.614238 9521.923198 5975.583106 16001.01882 4351.086387 3833.334574 0.962254806 1.128229882 0.977398 0.93810195 1.614420583 2.483979161 1.558847262 4.174177472 1.135065647 1 11.90438421 -1 0.560478567 0.981535059 141.8422054 0.833623265 0.396324858 32.22036029 0.260745181 0.065613382 5507.888932 0.1 1 140.8606704 up TVPVEAVTSK ddPTM_HeLa_Curcumin_4h_R1 2 TVPVEAVTSK 10 0 Q14247;Q14247-3;Q14247-2 Q14247 CTTN Src substrate cortactin 0 0 ; ; 123.75 0.0023751 9447000 3946.2 3000.49 3784.4 3514.72 3330.62 4511.4 3212.39 3250.4 3943.4 3116.03 FALSE FALSE TRUE 3633.854106 3259.838986 3924.653193 3500.17702 3290.904532 3575.684786 3302.521018 4241.431997 3510.818886 3224.311811 1.127016963 1.01101853 1.217206469 1.085557857 1.020653313 1.108976115 1.024256093 1.31545342 1.088858365 1 11.65477555 -13.52287875 0.254988174 0.27579497 1.121225305 0.04979738 0.093116749 57.49677086 0.763506888 20.9982837 0.047654749 3.00E-14 13.52287875 0.845430334 TVQS(ph)LEIDLDSMR ddPTM_HeLa_Curcumin_4h_R1 1 TVQSLEIDLDSMR 13 0 P05783;F8VZY9;CON__H-INV:HIT000015463 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 T(0.001)VQS(0.998)LEIDLDS(0.002)MR 97.073 0.0099616 5397200 2595.7 1798.1 1828.1 2444.6 2090.4 2368.6 1676 1180.5 2414.7 1895.2 TRUE FALSE FALSE 2390.247606 1953.519752 1895.850994 2434.484893 2065.473345 1877.32566 1723.024049 1540.429016 2149.813451 1961.058059 1.218856115 0.996156 0.966749039 1.241413982 1.053244363 0.957302438 0.878619601 0.785509133 1.096251812 1 10.93741653 -4.895481291 1.594276036 1.095280731 0.796530209 0.580275281 0.086482499 0.2785319 1.250930334 0.01544728 0.088671926 1.27E-05 4.895481291 -0.298750521 TVS(ph)ASS(ph)TGDLPK ddPTM_HeLa_Curcumin_4h_R1 1 TVSASSTGDLPK 12 0 P78362;H7C5L6;P78362-2 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 2 0 T(0.039)VS(0.955)AS(0.205)S(0.669)T(0.131)GDLPK 112.02 0.011882 20072000 6473.5 6071.4 5416.8 5629 5114.2 6468.5 3632.1 2974.8 5983.2 5826.7 TRUE FALSE FALSE 5961.115644 6596.184762 5617.551373 5605.708689 5053.216505 5126.860185 3734.006951 3881.802826 5326.857929 6029.177391 0.988711271 1.094043903 0.931727665 0.929763436 0.838127024 0.850341573 0.619322788 0.643836227 0.88351322 1 12.55774546 -5.003567911 0.774349592 1.001131601 0.550611712 0.809651647 0.06224028 0.254459702 0.194106603 0.007974973 0.079507353 9.92E-06 5.003567911 -0.450519888 TVS(ph)DNSLSNSR ddPTM_HeLa_Curcumin_4h_R1 1 TVSDNSLSNSR 11 0 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 0 T(0.178)VS(0.611)DNS(0.211)LSNSR 158.86 0.00037204 159320000 1907.5 1472.1 1526.6 1595.5 1549.4 1512.8 1317.6 1378.5 1620.3 1404.1 TRUE FALSE FALSE 1756.519362 1599.341764 1583.177139 1588.898244 1530.924417 1199.028227 1354.56831 1798.798304 1442.557144 1452.89237 1.208981063 1.100798515 1.089672691 1.093610426 1.053708071 0.825269821 0.932325296 1.238080907 0.992886447 1 10.50471212 -5.514517914 22.95381987 1.099033898 0.983194282 0.079944571 0.112151021 184.6990889 507069.576 0.017111576 0.035661692 3.06E-06 5.514517914 -0.115839616 TVS(ph)DNSLSNSRGEGKPDLK ddPTM_HeLa_Curcumin_4h_R1 1 TVSDNSLSNSRGEGKPDLK 19 2 H0Y7W6;B7ZL14;Q96RU3-4;Q96RU3-3;Q96RU3-5;Q96RU3-2;Q96RU3 H0Y7W6;Q96RU3-5 FNBP1 Formin-binding protein 1 1 0 T(0.042)VS(0.95)DNS(0.001)LS(0.006)NS(0.001)RGEGKPDLK 77.575 0.004834 0 1466.5 795.1 1125.3 1274 749.31 1316.1 790.46 881.52 1720.7 1289.2 TRUE FALSE FALSE 1350.424978 863.8249011 1167.004608 1268.728526 740.3749676 1043.126024 812.6381802 1150.29139 1531.943515 1333.999604 1.012312877 0.647545096 0.874816308 0.951071141 0.555003889 0.781953774 0.609174229 0.862287655 1.148383785 1 10.38154252 -7.27647022 24.47070276 1.005814427 0.754522141 0.533424276 0.125796584 348.4875827 567348.0159 0.019129669 0.021924269 5.29E-08 7.27647022 -0.251292286 TVS(ph)FEALPIMR ddPTM_HeLa_Curcumin_4h_R1 2 TVSFEALPIMR 11 0 O15084-2;O15084;O15084-4;O15084-1 O15084-2 ANKRD28 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A 1 0 T(0.481)VS(0.519)FEALPIMR;T(0.192)VS(0.808)FEALPIMR ; 112.5 0.0057926 31957000 2692.9 1793.41 2505.7 2200.76 1804.61 3618.2 3464.2 1869.65 2655.5 1960.82 TRUE FALSE FALSE 2479.754123 1948.424369 2598.563446 2191.653838 1783.091204 2867.744534 3561.396129 2439.697678 2364.198294 2028.958349 1.222180891 0.960307721 1.280737698 1.080186707 0.878821 1.413407296 1.755283015 1.202438522 1.165227613 1 10.98652353 -5.094684189 6.461000927 1.095246251 1.504016674 0.507195878 0.168611539 0.129919933 7.409887984 0.022748686 0.059021926 8.04E-06 5.094684189 0.408770422 TVS(ph)PPIR ddPTM_HeLa_Curcumin_4h_R1 1 TVSPPIR 7 0 Q9UHB6;F8VQE1;Q9UHB6-2;F8VS07;Q9UHB6-3;Q9UHB6-4;Q9UHB6-5 Q9UHB6;Q9UHB6-4 LIMA1 LIM domain and actin-binding protein 1 1 0 TVS(1)PPIR 86.136 0.017339 12475000 4311.9 3909.5 4039.1 4421.9 3952.8 5006.5 4074.6 3243.4 4860 4248.9 TRUE FALSE FALSE 3970.608565 4247.41976 4188.792599 4403.603349 3905.665442 3968.095465 4188.92231 4232.297729 4326.870159 4396.548959 0.903119379 0.966080396 0.952745583 1.001604529 0.888347993 0.902547772 0.952775085 0.962640873 0.984151479 1 12.10215582 -9.558774106 1.325365443 1.000065193 0.936856199 0.262078776 0.033262958 0.435142375 1.367398694 0.024612322 0.005776958 2.76E-10 9.558774106 -0.063208994 RLS(ph)S(ph)LRASTSKSESSQK ddPTM_HeLa_Curcumin_4h_R1 1 RLSSLRASTSKSESSQK 17 3 P62753;A2A3R5 P62753 RPS6 40S ribosomal protein S6 2 0 RLS(0.963)S(0.991)LRAS(0.036)T(0.008)S(0.001)KSESSQK 72.315 0.013401 33980000 8531 6295.4 6700.9 7805.9 5997.3 9560.8 5613.5 1948 9823.1 8386 TRUE FALSE FALSE 7855.762348 6839.546324 6949.241249 7773.601254 5925.786114 7577.782308 5770.999702 2541.936233 8745.530506 8677.412876 0.905311579 0.788201094 0.800842526 0.895843193 0.682897794 0.87327668 0.665059942 0.292937108 1.007849993 1 13.08304926 -4.031601717 0.437677632 0.951658518 2.16E-47 0.727298429 0.104082224 2.344823297 0.262194071 0.024832421 1.207015312 9.30E-05 4.031601717 -0.951658518 down TVS(ph)QQS(ph)FDGVSLDSSGPEDR ddPTM_HeLa_Curcumin_4h_R1 1 TVSQQSFDGVSLDSSGPEDR 20 0 H7C1J4;Q6BDS2 H7C1J4 UHRF1BP1 UHRF1-binding protein 1 2 0 T(0.041)VS(0.956)QQS(0.999)FDGVS(0.001)LDS(0.003)SGPEDR 190.1 7.94E-10 17762000 1273.4 1406.2 1131.8 1074.3 1251.2 2070.2 1429 1423.7 1614.7 1347.7 TRUE FALSE FALSE 1172.609046 1527.745662 1173.745504 1069.854831 1236.280257 1640.817184 1469.093894 1857.779576 1437.57145 1394.532475 0.840861771 1.095525339 0.841676709 0.767178141 0.886519518 1.176607368 1.053466965 1.332188106 1.030862655 1 10.44556582 -5.257808124 24.63813255 0.915626752 1.174025452 0.535615841 0.112365803 153.2762244 1039973.887 0.015735302 0.038441506 5.52E-06 5.257808124 0.2583987 TVS(ph)S(ph)PPTSPRPGS(ph)AATVSASTSNIIPPR ddPTM_HeLa_Curcumin_4h_R1 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 3 0 T(0.172)VS(0.556)S(0.57)PPT(0.483)S(0.483)PRPGS(0.597)AAT(0.07)VS(0.025)AS(0.027)T(0.012)S(0.006)NIIPPR 41.609 0.0089678 0 764.86 752.49 453.91 691.78 493.8 442.29 455.9 290.56 829.08 632.86 TRUE FALSE FALSE 704.3205239 817.5318826 470.7323039 688.9175977 487.9117575 350.5540684 468.691327 379.1504064 738.1319983 654.8518379 1.075541799 1.248422674 0.718837875 1.052020561 0.745071983 0.535318141 0.715721175 0.57898655 1.12717405 1 9.355024719 -5.724740802 1.331674593 1.040150764 0.604542049 0.671829982 0.135519906 0.186131428 0.656249092 0.019885888 0.053432568 1.88E-06 5.724740802 -0.435608714 TVS(ph)SPIPYTPSPSSSR ddPTM_HeLa_Curcumin_4h_R1 1 TVSSPIPYTPSPSSSR 16 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 0 T(0.03)VS(0.856)S(0.114)PIPYTPSPSSSR 178.14 1.98E-05 6969700 1888.6 1482.8 1530.8 2020.9 2281.4 2154.1 3139.4 926.85 2359.1 1718.3 TRUE FALSE FALSE 1739.115317 1610.966625 1587.532795 2012.538051 2254.195795 1707.315378 3227.483115 1209.442298 2100.312632 1778.010797 0.97812416 0.906049967 0.892870165 1.131904291 1.267818957 0.960239039 1.815221325 0.680222134 1.181271022 1 10.79604837 -6.06718074 4.895821887 0.975654868 1.209898883 0.091655852 0.277043353 0.291169132 13.5575552 0.035710566 0.060839956 8.57E-07 6.06718074 0.234244015 TVS(ph)VPSEGQFPEYPPEGATK ddPTM_HeLa_Curcumin_4h_R1 1 TVSVPSEGQFPEYPPEGATK 20 0 Q9UJF2-2 Q9UJF2-2 RASAL2 Ras GTPase-activating protein nGAP 1 0 T(0.098)VS(0.447)VPS(0.447)EGQFPEY(0.008)PPEGATK 84.68 0.0009502 8105900 3437.6 2362.7 3040.6 3108.3 3223.1 4172 3000.9 2118.4 3147.9 2876.9 TRUE FALSE FALSE 3165.510333 2566.92126 3153.287311 3095.438678 3184.666638 3306.680172 3085.097177 2764.290408 2802.583246 2976.872061 1.063367947 0.862288069 1.059261952 1.039829262 1.069802992 1.110790153 1.036355313 0.928588919 0.941452366 1 11.5395815 TVSAS(ph)STGDLPK ddPTM_HeLa_Curcumin_4h_R1 1 TVSASSTGDLPK 12 0 P78362;H7C5L6;P78362-2 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 0 TVSAS(0.5)S(0.5)TGDLPK 253.42 1.79E-35 45504000 6840.6 5164.1 5975.4 6568.6 5590 6745.5 4273.9 3331.9 7361.4 6122.8 TRUE FALSE FALSE 6299.159292 5610.461793 6196.85358 6541.420874 5523.342901 5346.407263 4393.814131 4347.780972 6553.872837 6335.566844 0.994253466 0.885550091 0.978105627 1.032491809 0.871799325 0.843871968 0.693515551 0.68624972 1.034457216 1 12.62925799 -5.054745509 1.19706798 0.989122343 0.658577116 0.862630621 0.045853145 0.138876046 0.327915033 0.006644278 0.039700951 8.82E-06 5.054745509 -0.330545228 TVSASS(ph)TGDLPK ddPTM_HeLa_Curcumin_4h_R1 1 TVSASSTGDLPK 12 0 P78362;H7C5L6;P78362-2 P78362 SRPK2 SRSF protein kinase 2;SRSF protein kinase 2 N-terminal;SRSF protein kinase 2 C-terminal 1 0 TVSAS(0.006)S(0.984)T(0.01)GDLPK 187.78 1.46E-05 80255000 6734.5 5448.8 5837.8 6317 5816.7 6331.4 4412.5 2861 6508.3 5593.7 TRUE FALSE FALSE 6201.457219 5919.769993 6054.154003 6290.861928 5747.339652 5018.19627 4536.302874 3733.30573 5794.355773 5788.080659 1.07141859 1.022751814 1.045969184 1.086864938 0.992961223 0.866987965 0.7837318 0.644998912 1.001084144 1 12.49886931 -4.795540921 1.252896743 1.038691454 0.628975327 0.946262114 0.031313501 0.115955229 0.269218967 0.005378329 0.047647326 1.60E-05 4.795540921 -0.409716127 TVSGPGT(ph)PEPR ddPTM_HeLa_Curcumin_4h_R1 2 TVSGPGTPEPR 11 0 Q9H3U1 Q9H3U1 UNC45A Protein unc-45 homolog A 1 0 TVS(0.001)GPGT(0.999)PEPR;T(0.018)VS(0.001)GPGT(0.981)PEPR ; 145.14 0.0028933 44481000 4321.5 3805.8 4274.1 4689.1 4779.8 5074.5 4489.1 4202.3 4097.1 3804.4 TRUE FALSE FALSE 3979.448715 4134.756394 4432.501906 4669.697747 4722.804007 4021.991499 4615.052064 5483.561925 3647.65838 3936.602617 1.010884029 1.050336241 1.125971386 1.186225332 1.199715711 1.021691009 1.1723439 1.392968115 0.926600609 1 11.94273537 -1 0.238333924 0.986266087 2.897315522 0.655509339 0.07538654 22.92633448 0.282184655 0.045999254 17.48260076 0.1 1 1.911049435 APS(ph)PSINR ddPTM_HeLa_Curcumin_4h_R1 2 APSPSINR 8 0 E9PFK9;Q9UJ41;Q9UJ41-4;Q9UJ41-3 E9PFK9 RABGEF1 Rab5 GDP/GTP exchange factor 1 0 APS(0.786)PS(0.214)INR;APS(0.5)PS(0.5)INR ; 133.99 0.0044108 124900000 6177 5284.3 5430.4 5794.5 5346 6098.1 4507.6 1938.46 6429.3 5088.1 TRUE FALSE FALSE 5688.083932 5741.051346 5631.655401 5770.523894 5282.252442 4833.28532 4634.071124 2529.48753 5724.021875 5264.911096 1.080376065 1.090436522 1.069658214 1.096034442 1.003293758 0.918018411 0.880180318 0.480442591 1.087202 1 12.36219345 -4.031286559 1.125664276 1.047229642 1.00E-16 0.944061848 0.042221418 0.458404129 0.333782518 0.007083878 0.639364376 9.30E-05 4.031286559 -1.047229642 down RSS(ph)PPPPPSGSSSR ddPTM_HeLa_Curcumin_4h_R1 2 RSSPPPPPSGSSSR 14 1 Q5VUA4;Q5VUA4-2 Q5VUA4 ZNF318 Zinc finger protein 318 1 0 RS(0.032)S(0.968)PPPPPSGSSSR;RS(0.158)S(0.842)PPPPPSGSSSR ; 125.67 0.00061724 26840600 656.07 513.91 445.39 442.66 508.74 577.43 329.66 217.57 698.13 554.285 TRUE FALSE FALSE 604.1413672 558.3300905 461.8965452 440.8283902 502.6736078 457.664509 338.9093724 283.9060914 621.5468856 573.5463625 1.05334356 0.973469848 0.805334277 0.768601144 0.876430644 0.79795556 0.590901442 0.495001119 1.083690746 1 9.163766301 -4.030426465 0.364852859 1.035445089 1.02E-17 0.8657616 0.067417293 1.909732183 0.155321928 0.023450061 0.896689869 9.32E-05 4.030426465 -1.035445089 down TVSLGAGAKDELHIVEAEAMNY(ph)EGSPIK ddPTM_HeLa_Curcumin_4h_R1 2 TVSLGAGAKDELHIVEAEAMNYEGSPIK 28 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 0 TVSLGAGAKDELHIVEAEAMNY(0.797)EGS(0.203)PIK;TVSLGAGAKDELHIVEAEAMNY(0.536)EGS(0.464)PIK ; 72.227 6.50E-05 149811000 5830 4850.6 4724.8 4929 6101.2 7772.9 6513.2 6253.47 5264.9 4915.6 TRUE FALSE FALSE 5368.549348 5269.86425 4899.905244 4908.605104 6028.447175 6160.712921 6695.942863 8160.124216 4687.353642 5086.416734 1.055467853 1.036066159 0.963331457 0.965041868 1.185205124 1.211208842 1.31643615 1.604297218 0.921543375 1 12.31243395 -3.994112208 0.72626357 1.018561097 2.168921276 0.916002889 0.057885459 0.689847538 0.197330609 0.008744384 0.707643645 0.000101365 3.994112208 1.150360178 TVSLGAGAKDELHIVEAEAMNY(ph)EGSPIKVTLATLK ddPTM_HeLa_Curcumin_4h_R1 3 TVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLK 35 2 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 0 TVSLGAGAKDELHIVEAEAMNY(0.753)EGS(0.247)PIKVTLATLK;TVSLGAGAKDELHIVEAEAMNY(0.673)EGS(0.322)PIKVT(0.004)LAT(0.001)LK;T(0.001)VS(0.001)LGAGAKDELHIVEAEAMNY(0.605)EGS(0.361)PIKVT(0.014)LAT(0.017)LK ;; 90.211 9.16E-10 186358000 9838.1 8800 8577.8 7686.5 7645.5 21992.8 14969.3 13727.6 13382.7 11257.2 TRUE FALSE FALSE 9059.404004 9560.632788 8895.700814 7654.6953 7554.332406 17431.24537 15389.29827 17913.08205 11914.65129 11648.38686 0.777738936 0.820768824 0.763685214 0.657146383 0.64853035 1.496451447 1.321152744 1.537816546 1.022858481 1 13.50784256 -5.25320294 24.98176617 0.844447953 1.438741541 0.834907585 0.129614523 208.8757553 633534.632 0.020511596 0.051331878 5.58E-06 5.25320294 0.594293588 TVSLGAGAKDELHIVEAEAMNYEGS(ph)PIK ddPTM_HeLa_Curcumin_4h_R1 5 TVSLGAGAKDELHIVEAEAMNYEGSPIK 28 1 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 0 TVSLGAGAKDELHIVEAEAMNY(0.117)EGS(0.883)PIK;TVSLGAGAKDELHIVEAEAMNY(0.461)EGS(0.539)PIK;TVSLGAGAKDELHIVEAEAMNY(0.001)EGS(0.999)PIK;TVSLGAGAKDELHIVEAEAMNY(0.001)EGS(0.999)PIK;TVSLGAGAKDELHIVEAEAMNY(0.005)EGS(0.995)PIK ;;;; 139.61 1.74E-10 223189300 16965.6 14105.4 15231.3 13665.4 17235.2 22506.6 19304.7 17219.9 16099.9 13426.9 TRUE FALSE FALSE 15622.75486 15324.60792 15795.78538 13608.8562 17029.6815 17838.47746 19846.33793 22470.16824 14333.78125 13893.48378 1.124466341 1.103006861 1.136920418 0.979513592 1.225731557 1.283945607 1.428463749 1.617317053 1.031690934 1 13.76212078 -4.246370238 0.664908219 1.058768587 2.001179722 0.910330573 0.057570264 0.690116142 0.206544463 0.011304797 0.493475445 5.67E-05 4.246370238 0.942411136 TVSLGAGAKDELHIVEAEAMNYEGS(ph)PIKVTLATLK ddPTM_HeLa_Curcumin_4h_R1 3 TVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLK 35 2 P06748;P06748-3;P06748-2 P06748 NPM1 Nucleophosmin 1 0 T(0.001)VS(0.002)LGAGAKDELHIVEAEAMNY(0.465)EGS(0.502)PIKVT(0.023)LAT(0.008)LK;TVSLGAGAKDELHIVEAEAMNY(0.198)EGS(0.792)PIKVT(0.007)LAT(0.002)LK;TVSLGAGAKDELHIVEAEAMNY(0.13)EGS(0.779)PIKVT(0.058)LAT(0.033)LK ;; 48.865 0.0036017 154001400 4123.46 3637.11 3173.51 3347.72 2937.34 8213.03 5396.21 6057.87 4945.82 3977.31 TRUE FALSE FALSE 3797.08379 3951.485582 3291.123072 3333.868022 2902.314139 6509.554998 5547.613129 7904.886676 4403.27592 4115.521226 0.922625247 0.960142194 0.799685603 0.810071881 0.705211802 1.581708522 1.347973397 1.920749825 1.06991938 1 12.00685944 -5.249018468 24.69264579 0.923124782 1.589926965 0.799391766 0.165041245 212.0382284 421528.7058 0.021840849 0.055241948 5.64E-06 5.249018468 0.666802182 TLLLMS(ph)FTK ddPTM_HeLa_Curcumin_4h_R1 1 TLLLMSFTK 9 0 F8WE24;P48553-2;P48553 F8WE24 TRAPPC10 Trafficking protein particle complex subunit 10 1 0 TLLLMS(0.775)FT(0.225)K 104.75 0.010847 506690000 3196.7 2987.4 2746.6 3111.2 2851.8 3308.5 2344.9 1060.5 3010.3 3117.1 TRUE FALSE FALSE 2943.677822 3245.617544 2848.391412 3098.326679 2817.794148 2622.279806 2410.691583 1383.841568 2680.077621 3225.418993 0.912649745 1.006262303 0.88310741 0.96059665 0.873621118 0.813004391 0.747404163 0.429042419 0.830923867 1 11.65527087 -4.026347314 0.824224912 0.956610847 1.69E-15 0.869234531 0.057632425 0.603277277 0.230109026 0.007180978 0.574104682 9.41E-05 4.026347314 -0.956610847 down TVSLTPS(ph)PT(ph)TQVETPDLVDHDNTSPLFR ddPTM_HeLa_Curcumin_4h_R1 1 TVSLTPSPTTQVETPDLVDHDNTSPLFR 28 0 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 2 0 T(0.002)VS(0.011)LT(0.195)PS(0.616)PT(0.592)T(0.582)QVET(0.002)PDLVDHDNTSPLFR 110.06 1.39E-09 13343000 2516.4 2251.4 2256 2014.9 2185 1657.9 1085.1 2234.6 2750.4 2589.4 TRUE FALSE FALSE 2317.224285 2446.000984 2339.609345 2006.562878 2158.945302 1314.032852 1115.544986 2915.919253 2448.688001 2679.381457 0.864835531 0.912897631 0.873190093 0.748890335 0.805762575 0.490423955 0.416344221 1.088280747 0.91390048 1 11.38768427 -6.143127411 1.18433133 0.936091907 0.65468231 0.261193773 0.172497232 0.393256345 1.088399543 0.028120605 0.060020981 7.19E-07 6.143127411 -0.281409597 VDIDT(ph)PDINIEGSEGK ddPTM_HeLa_Curcumin_4h_R1 4 VDIDTPDINIEGSEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK;VDIDT(1)PDINIEGSEGK ;;; 174.35 0.00016091 253040400 21909.4 15338.5 23944.2 23179.4 21411.9 23910.2 27009 30639.8 18685.8 15286.2 TRUE FALSE FALSE 20175.24787 16664.29159 24831.59312 23083.48978 21156.57708 18950.955 27766.79985 39981.73397 16636.01449 15817.39431 1.275510206 1.053542149 1.569891515 1.459373733 1.337551348 1.198108527 1.7554598 2.527706725 1.051754427 1 13.94922434 -1 0.671881633 1.167668352 141.8328935 0.824918753 0.181748129 71.51299278 0.394562758 0.033937988 15059.55386 0.1 1 140.6652252 up TVSLTPSPTTQVETPDLVDHDNT(ph)SPLFR ddPTM_HeLa_Curcumin_4h_R1 1 TVSLTPSPTTQVETPDLVDHDNTSPLFR 28 0 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 0 TVSLTPS(0.003)PT(0.127)T(0.127)QVET(0.081)PDLVDHDNT(0.366)S(0.295)PLFR 62.958 0.0015291 49880000 2215.2 1817.2 1642.8 2061.7 2336 2573 2633.6 2802.1 2205.3 1930.3 TRUE FALSE FALSE 2039.864583 1974.270671 1703.683613 2053.169232 2308.144726 2039.330796 2707.491728 3656.447391 1963.384107 1997.377781 1.02127129 0.988431277 0.852960131 1.027932348 1.155587464 1.021004046 1.355523103 1.830623843 0.982980849 1 10.96389151 -4.120996884 1.237054745 1.002318236 2.430684229 0.931973135 0.069566551 0.33001666 0.337757172 0.010062832 0.649685334 7.57E-05 4.120996884 1.428365993 TVSLTPSPTTQVETPDLVDHDNTS(ph)PLFR ddPTM_HeLa_Curcumin_4h_R1 1 TVSLTPSPTTQVETPDLVDHDNTSPLFR 28 0 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 0 TVSLTPS(0.001)PT(0.012)T(0.034)QVET(0.29)PDLVDHDNT(0.21)S(0.453)PLFR 54.308 0.0023115 23990000 2989.2 2043.6 2286.8 2216.7 2358.5 3298.8 2982.5 2621.3 2594.2 2490.9 TRUE FALSE FALSE 2752.601666 2220.239678 2371.55082 2207.527883 2330.376428 2614.591695 3066.180923 3420.522303 2309.62275 2577.45859 1.067951849 0.861406537 0.920112094 0.856474626 0.904137291 1.014406868 1.189614039 1.32709108 0.896085299 1 11.33173353 -4.602682794 2.547640633 0.989003865 1.319283388 0.712934594 0.07834299 0.158061153 1.870252093 0.012876992 0.081103008 2.50E-05 4.602682794 0.330279523 TVSPDRLELEAAQK ddPTM_HeLa_Curcumin_4h_R1 2 TVSPDRLELEAAQK 14 1 Q14974;J3QR48 Q14974 KPNB1 Importin subunit beta-1 0 0 ; ; 183.81 2.19E-08 8996300 2049.2 2004.36 2041.15 2193.78 2285.4 1830.46 1544.91 1691.12 3018 2427.55 FALSE FALSE TRUE 1887.003658 2177.607947 2116.796815 2184.70272 2258.148098 1450.801962 1588.256017 2206.734703 2686.932951 2511.907182 0.751223481 0.866914177 0.842705029 0.869738633 0.898977524 0.577569893 0.632290886 0.878509652 1.069678438 1 11.29456744 -13.52287875 0.217629773 2.139970198 0.745745049 0.472591608 0.103931486 39.27439205 0.49531007 19.10704234 0.089725232 3.00E-14 13.52287875 -1.394225149 TVSPGS(ph)VSPIHGQGQVVENLK ddPTM_HeLa_Curcumin_4h_R1 1 TVSPGSVSPIHGQGQVVENLK 21 0 A0A087WVF7;Q9NZM3-4;Q9NZM3-3;Q9NZM3-2;Q9NZM3 A0A087WVF7 ITSN2 Intersectin-2 1 0 T(0.002)VS(0.007)PGS(0.496)VS(0.496)PIHGQGQVVENLK 102.92 3.77E-05 26219000 2659.4 2384 2298.3 2300.2 2349.2 2432.3 1026.8 1125.1 2578.5 2284.9 TRUE FALSE FALSE 2448.905684 2590.062337 2383.47702 2290.682382 2321.187324 1927.813562 1055.609245 1468.137811 2295.645001 2364.300105 1.035784619 1.095487976 1.008111032 0.968862784 0.981765098 0.815384459 0.446478534 0.620960853 0.970961764 1 11.20719746 -5.000098325 2.665721081 1.017335885 0.531773951 0.914228642 0.057479125 0.046585345 0.657171005 0.007530441 0.026202673 1.00E-05 5.000098325 -0.485561934 TVSPGSVS(ph)PIHGQGQVVENLK ddPTM_HeLa_Curcumin_4h_R1 1 TVSPGSVSPIHGQGQVVENLK 21 0 A0A087WVF7;Q9NZM3-4;Q9NZM3-3;Q9NZM3-2;Q9NZM3 A0A087WVF7 ITSN2 Intersectin-2 1 0 TVSPGS(0.035)VS(0.964)PIHGQGQVVENLK 115.01 5.94E-06 23690000 5275.3 4226.7 4185.3 4516.3 4978.3 4831 2403.7 2597.8 5394.9 4570.8 TRUE FALSE FALSE 4857.754439 4592.037114 4340.4109 4497.612747 4918.937024 3828.996143 2471.141353 3389.857261 4803.092967 4729.63496 1.027088661 0.970907301 0.917705264 0.950942892 1.040024667 0.809575406 0.522480355 0.716727039 1.015531433 1 12.20751312 -5.017767228 3.726480165 0.998643881 0.621620583 0.868813927 0.057410656 0.049099828 1.477698273 0.00790983 0.02401097 9.60E-06 5.017767228 -0.377023298 TVSQQS(ph)FDGVSLDSSGPEDR ddPTM_HeLa_Curcumin_4h_R1 1 TVSQQSFDGVSLDSSGPEDR 20 0 H7C1J4;Q6BDS2 H7C1J4 UHRF1BP1 UHRF1-binding protein 1 1 0 TVSQQS(0.851)FDGVS(0.149)LDSSGPEDR 229.37 2.57E-25 15842000 1465.9 1214.1 989.06 1251.7 1265.9 1802.6 975.46 827.49 1755.4 1129.8 TRUE FALSE FALSE 1349.872468 1319.041394 1025.715434 1246.520797 1250.804969 1428.720441 1002.828782 1079.787892 1562.837012 1169.060466 1.154664372 1.128291848 0.877384416 1.066258618 1.069923247 1.222109961 0.857807454 0.923637334 1.336831633 1 10.19113384 -4.73457453 24.99993665 1.071745041 0.890722207 0.304693384 0.121687037 179.7433577 167263.1533 0.013108932 0.049022089 1.84E-05 4.73457453 -0.181022833 TVSS(ph)PPT(ph)SPRPGSAATVSASTSNIIPPR ddPTM_HeLa_Curcumin_4h_R1 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 2 0 T(0.009)VS(0.164)S(0.746)PPT(0.561)S(0.515)PRPGS(0.004)AATVSAST(0.001)SNIIPPR 82.91 1.42E-05 205490000 2043.7 1779 1937.6 1838.9 1881.5 1797.4 1178.3 1244.1 2097.1 1625.4 TRUE FALSE FALSE 1881.938988 1932.768833 2009.40916 1831.291119 1859.064341 1424.598979 1211.359927 1623.420363 1867.053377 1681.882529 1.118947938 1.149169933 1.194738114 1.088834141 1.105347317 0.847026445 0.720240508 0.965240042 1.110097373 1 10.71586123 -5.244767909 8.857121725 1.0805561 0.831373732 0.710161681 0.076008905 0.124383341 58.95650221 0.011969218 0.029738481 5.69E-06 5.244767909 -0.249182367 TVSSDGCST(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 TVSSDGCSTPSR 12 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 TVSSDGCS(0.026)T(0.942)PS(0.032)R 142.19 0.0022379 0 3032.8 2712 3069.6 2564.2 3359.9 2872.6 2504 2465.4 3068.4 2504.6 TRUE FALSE FALSE 2792.75068 2946.413196 3183.362076 2553.59002 3319.835387 2276.790379 2574.255501 3217.089111 2731.804197 2591.634664 1.077601993 1.136893728 1.228322078 0.985320213 1.280981241 0.878515175 0.993294131 1.241335886 1.054085375 1 11.33964664 -8.554745306 0.957589187 1.008632096 1.097938343 0.052974857 0.121247011 0.935974924 1.749731015 0.043454438 0.023489464 2.79E-09 8.554745306 0.089306247 TVSSPIPYT(ph)PSPSSSR ddPTM_HeLa_Curcumin_4h_R1 1 TVSSPIPYTPSPSSSR 16 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 0 T(0.005)VS(0.036)S(0.011)PIPY(0.239)T(0.434)PS(0.057)PS(0.007)S(0.106)S(0.106)R 102.63 0.0064523 6851000 1128.1 1125.6 1334.7 1468.2 1648.7 1670 2306.5 535.39 1444.2 1382.2 TRUE FALSE FALSE 1038.809695 1222.891848 1384.165156 1462.124977 1629.040329 1323.623175 2371.214182 698.6279464 1285.774873 1430.231347 0.726322841 0.855030797 0.967791091 1.02229963 1.139004772 0.92546089 1.657923515 0.488471986 0.898997827 1 10.48203281 -6.376478322 2.090298181 0.866648103 1.084776256 0.077197308 0.274560562 0.517704851 4.429709853 0.041351975 0.068496844 4.20E-07 6.376478322 0.218128153 TVSSPIPYTPSPSSS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 TVSSPIPYTPSPSSSR 16 0 Q16204 Q16204 CCDC6 Coiled-coil domain-containing protein 6 1 0 T(0.069)VS(0.028)S(0.099)PIPY(0.116)T(0.048)PS(0.132)PS(0.082)S(0.207)S(0.219)R 113.67 0.0013501 35935000 2254.5 2169.4 2207.8 2705.4 2430.2 981.84 1008.9 926.58 2503.7 1946.9 TRUE FALSE FALSE 2076.053946 2356.913269 2289.62301 2694.205772 2401.221452 778.1953164 1037.207019 1209.089977 2229.050374 2014.55463 1.0305275 1.169942594 1.136540542 1.33737042 1.191936628 0.386286529 0.514856735 0.600177309 1.106473034 1 10.97624521 -5.261123615 24.99995086 1.071167679 0.501881826 0.863161126 0.114295567 9.20828254 729002.5371 0.019118808 0.045608063 5.48E-06 5.261123615 -0.569285853 TVSSPPT(ph)S(ph)PRPGSAATVSASTSNIIPPR ddPTM_HeLa_Curcumin_4h_R1 3 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 2 0 T(0.009)VS(0.103)S(0.33)PPT(0.778)S(0.778)PRPGS(0.002)AATVSASTSNIIPPR;T(0.022)VS(0.08)S(0.29)PPT(0.773)S(0.773)PRPGS(0.037)AAT(0.005)VS(0.002)AS(0.003)T(0.011)S(0.004)NIIPPR;T(0.035)VS(0.097)S(0.245)PPT(0.807)S(0.807)PRPGS(0.003)AAT(0.001)VSAS(0.001)T(0.001)S(0.001)NIIPPR ;; 81.726 1.63E-05 386944000 6386.2 5564.7 5309.4 5423.1 5242.4 6449.6 4543.8 3608.26 6008.4 5650.6 TRUE FALSE FALSE 5880.725531 6045.687872 5506.171035 5400.660649 5179.887804 5111.880258 4671.286799 4708.401864 5349.293552 5846.957929 1.005775243 1.033988605 0.941715521 0.923670174 0.885911591 0.874280321 0.798926015 0.805273771 0.914884905 1 12.5134705 -5.60941806 0.745493481 1.006138684 0.790161381 0.784444216 0.03545319 0.141563818 0.132900883 0.003824573 0.017625564 2.46E-06 5.60941806 -0.215977304 TVSSPPT(ph)SPRPGSAATVSASTSNIIPPR ddPTM_HeLa_Curcumin_4h_R1 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 0 T(0.015)VS(0.061)S(0.246)PPT(0.369)S(0.099)PRPGS(0.003)AAT(0.011)VS(0.006)AS(0.022)T(0.073)S(0.095)NIIPPR 54.855 0.0038356 110910000 707.97 627.29 733.94 570.7 661.24 976.27 616.38 624.04 768.07 630.68 TRUE FALSE FALSE 651.9334275 681.5101525 761.140462 568.3385946 653.3551449 773.7805972 633.6739639 814.3069233 683.8146426 652.5960831 0.998984585 1.044306226 1.166327046 0.870888762 1.001163142 1.185696049 0.971004853 1.247796216 1.047837491 1 9.350046518 -1.000008022 0.940776291 1.010614573 142.8380443 0.295080911 0.090737956 931.5926794 1.604809193 0.012736203 284302.4633 0.099998153 1.000008022 141.8274298 TVSSPPTS(ph)PRPGSAATVSASTSNIIPPR ddPTM_HeLa_Curcumin_4h_R1 1 TVSSPPTSPRPGSAATVSASTSNIIPPR 28 1 O76094-2;O76094 O76094-2 SRP72 Signal recognition particle subunit SRP72 1 0 T(0.022)VS(0.019)S(0.083)PPT(0.22)S(0.628)PRPGS(0.022)AAT(0.004)VS(0.001)AS(0.001)T(0.001)S(0.001)NIIPPR 56.986 0.0016944 129580000 3590 2873.4 2975.6 3453.5 2786.3 3950.1 3129.7 2310.4 3057.8 3008 TRUE FALSE FALSE 3305.847712 3121.763892 3085.878354 3439.210332 2753.075192 3130.804733 3217.510959 3014.830324 2722.36699 3112.527776 1.062110268 1.0029674 0.991438013 1.104957314 0.884514257 1.005872062 1.033729236 0.968611541 0.874648256 1 11.603871 -5.776105231 24.99997 1.029384954 0.979841574 0 0.068206897 290.0960375 494508.9722 0.007083764 0.01287911 1.67E-06 5.776105231 -0.04954338 TVSTSS(ph)QPEENVDR ddPTM_HeLa_Curcumin_4h_R1 1 TVSTSSQPEENVDR 14 0 P42684-2;P42684-3;P42684-4;P42684-10;P42684-6;P42684;P42684-7;P42684-5 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 0 TVST(0.003)S(0.027)S(0.97)QPEENVDR 209.53 1.90E-09 10741000 1816.4 1901.3 2257.6 1918.1 1700.8 2547.8 1604.2 1440.5 1755.6 1640.8 TRUE FALSE FALSE 1672.630023 2065.6399 2341.268642 1910.16341 1680.519071 2019.35756 1649.209535 1879.701819 1563.015072 1697.817678 0.985164688 1.216644123 1.37898708 1.125069809 0.989811269 1.189384223 0.971370222 1.107128194 0.920602425 1 10.72946583 -7.280548644 24.22354707 0.992994427 1.138069513 0.326704136 0.110948165 546.7230559 693042.7442 0.019363095 0.022162733 5.24E-08 7.280548644 0.145075086 AEGAATEEEGTPKES(ph)EPQAAAEPAEAK ddPTM_HeLa_Curcumin_4h_R1 2 AEGAATEEEGTPKESEPQAAAEPAEAK 27 1 P80723;P80723-2 P80723 BASP1 Brain acid soluble protein 1 1 0 AEGAATEEEGT(0.374)PKES(0.626)EPQAAAEPAEAK;AEGAAT(0.002)EEEGT(0.479)PKES(0.519)EPQAAAEPAEAK ; 121.92 4.88E-09 127119000 4032.6 3230.4 3301 4172.1 3676.4 5650.3 4511.1 5497.2 5413.9 3345.74 TRUE FALSE FALSE 3713.415455 3509.621382 3423.337964 4154.836956 3632.561331 4478.364088 4637.669325 7173.270974 4820.008715 3462.004216 1.072620142 1.013754219 0.988831252 1.200124753 1.049265427 1.293575573 1.339590895 2.071999491 1.392259632 1 11.75739177 -1 0.747745885 1.035947922 180.6293906 0.820613227 0.131639095 45.94060395 0.18794291 0.010262077 13907.53021 0.1 1 179.5934427 up SASS(ph)DTSEELNSQDSPPK ddPTM_HeLa_Curcumin_4h_R1 1 SASSDTSEELNSQDSPPK 18 0 J3QRP6;O14745-2;O14745 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 1 0 S(0.001)AS(0.074)S(0.853)DT(0.073)SEELNSQDSPPK 289.5 2.68E-81 65069000 5366.1 4171.9 4927.5 4687.8 6090.3 6628.8 6869.3 6492.3 3682.5 3719.4 TRUE FALSE FALSE 4941.367523 4532.500446 5110.117485 4668.403126 6017.67715 5253.912158 7062.03407 8471.772383 3278.538963 3848.648873 1.283922666 1.177686143 1.327769213 1.212997932 1.563581753 1.365131591 1.834938521 2.201232864 0.851867518 1 11.91013634 -1 0.358439288 1.108422325 14.62176686 0.869345188 0.136179723 12.46726016 0.154992746 0.033964451 116.264182 0.1 1 13.51334454 up TVTELVTK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 TVTELVTKK 9 1 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 0 1 ; TVTELVTK(1)K;TVTELVTK(1)K 171.56 2.32E-12 32153000 7680.1 6511.9 6858.1 6299 6899.7 7528.9 6239.3 3993.5 8136.3 5832.7 FALSE TRUE FALSE 7072.211981 7074.75962 7112.267219 6272.936407 6817.425584 5967.321272 6414.357966 5211.099766 7243.768246 6035.385891 1.171791184 1.172213301 1.178427916 1.039359623 1.129575757 0.988722408 1.062791689 0.863424454 1.200216254 1 12.5592303 -3.352745654 0.920759259 1.095624008 1.87E-08 0.514326862 0.072124109 7.179333079 1.3315574 0.012565914 11.76493283 0.000443869 3.352745654 -1.095623989 TVTIVVR ddPTM_HeLa_Curcumin_4h_R1 2 TVTIVVR 7 0 P50991-2;P50991 P50991-2 CCT4 T-complex protein 1 subunit delta 0 0 ; ; 114.72 0.010797 31415000 7386.4 6209.8 6594.1 6677.6 6619.8 7009.2 5987 6191.9 7056.9 6390.2 FALSE FALSE TRUE 6801.758646 6746.547442 6838.483147 6649.969861 6540.863209 5555.41291 6154.979107 8079.781806 6282.775725 6612.258974 1.02865884 1.020309015 1.034212842 1.005703177 0.989202515 0.840168682 0.930843624 1.221939709 0.950170849 1 12.69092751 -5.787011866 4.302836019 1.015892216 0.979500066 0 0.092598103 0.662214821 27.77013477 0.012841958 0.024784806 1.63E-06 5.787011866 -0.03639215 TVTLELLDNGAGADAT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 TVTLELLDNGAGADATK 17 0 A8K7I4 A8K7I4 CLCA1 Calcium-activated chloride channel regulator 1 1 0 TVTLELLDNGAGADAT(1)K 157.23 0.00047995 197520000 4316.6 3234.6 3654 3433.3 3333.8 6414.1 4379.3 4424.7 4397.8 4077.2 TRUE FALSE FALSE 3974.936555 3514.184411 3789.420454 3419.093914 3294.046612 5083.743358 4502.171372 5773.770661 3915.372343 4218.882397 0.942177615 0.832965719 0.898204808 0.810426457 0.780786546 1.204997646 1.067147872 1.368554541 0.928059134 1 12.04264516 -5.239550255 24.20875931 0.932075861 1.198924886 0.679195722 0.099782397 304.3261208 336575.1266 0.01510451 0.038467557 5.76E-06 5.239550255 0.266849026 TVTNAVVTVPAYFNDSQR ddPTM_HeLa_Curcumin_4h_R1 3 TVTNAVVTVPAYFNDSQR 18 0 P11142;P11142-2;E9PN89;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PI65 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 ;; ;; 265.64 8.65E-77 28779300 2235.78 1921.34 2105.13 2367.83 2347.95 2900.36 2626.31 2144.56 2254.97 2393.89 FALSE FALSE TRUE 2058.815654 2087.412068 2183.14797 2358.032547 2319.95223 2298.792642 2699.99719 2798.426472 2007.605433 2477.077499 0.831147049 0.842691466 0.881340196 0.951941369 0.936568287 0.928026129 1.089993022 1.129729075 0.810473404 1 11.27442329 -4.731630545 3.316272232 0.913260103 1.123945462 0.68268909 0.05742615 0.129065848 2.854208515 0.009754371 0.041471371 1.86E-05 4.731630545 0.210685359 TVTPAK(ac)AVTTPGK ddPTM_HeLa_Curcumin_4h_R1 2 TVTPAKAVTTPGK 13 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 ; TVTPAK(1)AVTTPGK;TVTPAK(1)AVTTPGK 164.48 1.65E-05 23164000 7382.8 6506.9 6201 6784.5 6586.5 9841.5 8129.7 6626.5 8240.5 6513.6 FALSE TRUE FALSE 6798.44359 7069.327442 6430.814515 6756.427537 6507.960289 7800.261963 8357.797502 8646.889345 7336.537767 6739.947115 1.00867907 1.048869868 0.954134269 1.002445186 0.96558032 1.157317977 1.240039033 1.282931334 1.088515628 1 12.71852156 -5.020195312 2.615816313 1.001381744 1.264204824 0.873170558 0.039009564 0.043774855 0.590578748 0.003791818 0.013037774 9.55E-06 5.020195312 0.262823079 TVTPAK(ac)AVTTPGKK ddPTM_HeLa_Curcumin_4h_R1 1 TVTPAKAVTTPGKK 14 2 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 TVTPAK(1)AVTTPGKK 155.09 0.00018306 54957000 5090.6 4599.2 5142.6 4791.2 5134.7 5447.3 5581.1 4521.5 5653 4516.7 FALSE TRUE FALSE 4687.673638 4996.734354 5333.18928 4771.375284 5073.472056 4317.468576 5737.690645 5900.084536 5032.880043 4673.654989 1.002999505 1.069127774 1.141117454 1.020908752 1.085546979 0.923788467 1.22766671 1.262413368 1.076861697 1 12.19033552 -4.685348471 7.278780315 1.019619787 1.250268789 0.645849205 0.059267949 0.088813533 7.083140445 0.007995637 0.030245279 2.06E-05 4.685348471 0.230649002 LSTS(ph)SETVSSTAASK ddPTM_HeLa_Curcumin_4h_R1 2 LSTSSETVSSTAASK 15 0 Q9P242 Q9P242 NYAP2 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 1 0 LS(0.003)T(0.04)S(0.721)S(0.232)ET(0.002)VS(0.002)STAASK;LS(0.001)T(0.015)S(0.968)S(0.015)ET(0.001)VSSTAASK ; 97.2 0.0049212 29427100 5909.3 4736 5228.1 5367.6 5206.9 6630.8 4701.2 1992.18 6300.1 5470.3 TRUE FALSE FALSE 5441.57267 5145.358737 5421.857985 5345.390293 5144.811118 5255.497335 4833.103019 2599.586511 5608.994792 5660.392518 0.96134193 0.909010942 0.957859012 0.944349756 0.908914197 0.928468709 0.853845913 0.459259054 0.990919759 1 12.46668638 -4.026211818 1.497733109 0.966356685 1.34E-16 0.957498964 0.030851951 0.321333264 0.419854045 0.005275917 0.541653573 9.41E-05 4.026211818 -0.966356685 down TVTPASS(ph)AKTSPAK ddPTM_HeLa_Curcumin_4h_R1 1 TVTPASSAKTSPAK 14 1 A0A1C7CYX9;Q16555-2;Q16555 A0A1C7CYX9 DPYSL2 Dihydropyrimidinase-related protein 2 1 0 TVTPAS(0.003)S(0.513)AKT(0.119)S(0.364)PAK 75.445 0.010906 29056000 7449.7 4027.6 2971.5 5040.2 1954.6 5846.9 3149.4 4093.1 14285 8191.7 TRUE FALSE FALSE 6860.048384 4375.727797 3081.626404 5019.344988 1931.292672 4634.187032 3237.763688 5341.067348 12717.97124 8476.360965 0.809315272 0.516227166 0.363555353 0.592158004 0.227844553 0.546718934 0.381975673 0.630113249 1.50040463 1 13.04922931 -7.401996825 1.50483324 0.93575077 0.446919212 0.631178629 0.213423911 0.117814158 0.516994279 0.022449458 0.025174748 3.96E-08 7.401996825 -0.488831558 TWDDDS(ph)DPESETDPDAQAK ddPTM_HeLa_Curcumin_4h_R1 2 TWDDDSDPESETDPDAQAK 19 0 K7EL01;Q5XUX1;Q5XUX1-2 K7EL01 FBXW9 F-box/WD repeat-containing protein 9 1 0 T(0.024)WDDDS(0.976)DPESETDPDAQAK;T(0.01)WDDDS(0.99)DPESETDPDAQAK ; 199.75 3.12E-11 68336000 9814.9 7650.6 7485.3 8756.3 8625.4 9997.8 6972.6 6728.8 9276.3 7962.3 TRUE FALSE FALSE 9038.040308 8311.883774 7762.711803 8720.068751 8522.547738 7924.143582 7168.23239 8780.380144 8258.713098 8238.989332 1.096984101 1.008847498 0.942192239 1.058390586 1.034416649 0.961785877 0.870037829 1.065710828 1.002393955 1 13.00825166 -5.253241874 6.072510645 1.036351711 0.955757268 0.10560218 0.059759033 0.169878011 28.15510285 0.008837616 0.021701192 5.58E-06 5.253241874 -0.080594443 TWDHFWLNEGHTVYLER ddPTM_HeLa_Curcumin_4h_R1 1 TWDHFWLNEGHTVYLER 17 0 P09960-2;P09960;P09960-3;P09960-4 P09960-2 LTA4H Leukotriene A-4 hydrolase 0 0 104.2 0.00045348 13619000 2807.7 2384.8 2870.6 2299.3 2337.6 5436.4 3200.8 3163.5 2925.7 2866 FALSE FALSE TRUE 2585.467582 2590.931486 2976.986961 2289.786106 2309.725647 4308.829359 3290.605833 4128.036587 2604.75803 2965.593287 0.871821363 0.873663795 1.003841955 0.772117376 0.778841002 1.452940084 1.109594444 1.391976643 0.878326115 1 11.53410504 -5.263130456 24.99999986 0.91591923 1.2973128 0.752785962 0.113062868 60.51835593 894680.8939 0.016046763 0.037713277 5.46E-06 5.263130456 0.381393569 TWNDPSVQQDIK ddPTM_HeLa_Curcumin_4h_R1 2 TWNDPSVQQDIK 12 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 0 ; ; 198.97 1.47E-14 6615100 6207.4 5686.8 6480.6 6396.2 6090.2 8453.6 5144.2 4429.9 6465.1 5574 FALSE FALSE TRUE 5716.07774 6178.341652 6720.776737 6369.734219 6017.578343 6700.228068 5288.532407 5780.556117 5755.894705 5767.696085 0.991050439 1.071197504 1.165244603 1.104381043 1.043324449 1.161681886 0.916922863 1.002229665 0.997953883 1 12.49377943 -7.260337654 24.10937893 0.995773819 1.068711574 0.178246984 0.068840165 75.69662793 1656490.433 0.011791023 0.014002834 5.49E-08 7.260337654 0.072937755 QLLLQQQQQQQVSGLKS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 QLLLQQQQQQQVSGLKSPK 19 1 Q9H334-8;Q9H334-4;A0A3B3IST0;A0A3B3IUB6;A0A3B3IRS5;C9J0F0;Q9H334;Q9H334-3;Q9H334-7;Q9H334-6;A0A3B3IST6;A0A087WVT2;G5E965;A0A3B3IU15;A0A3B3IU08;A0A3B3IRY1 Q9H334-8 FOXP1 Forkhead box protein P1 1 0 QLLLQQQQQQQVS(0.027)GLKS(0.973)PK 108.5 0.0002405 63214000 1666.7 1230.9 1363.1 1413.6 1085.3 1650.7 1091.3 431.97 1386.4 1388.1 TRUE FALSE FALSE 1534.778936 1337.293511 1413.617685 1407.750898 1072.358506 1308.326213 1121.918941 563.6756645 1234.315389 1436.336372 1.068537264 0.931044801 0.984182893 0.980098343 0.746592879 0.910877312 0.781097634 0.392439874 0.85934981 1 10.48817793 -4.025684235 0.605531456 1.022559873 7.24E-22 0.721465656 0.097024459 1.298387648 0.266866882 0.014791542 0.983934786 9.43E-05 4.025684235 -1.022559873 down TYAENLS(ph)PHEGR ddPTM_HeLa_Curcumin_4h_R1 1 TYAENLSPHEGR 12 0 E9PQ01 E9PQ01 PCF11 1 0 TYAENLS(1)PHEGR 76.391 0.0085575 0 2258.5 1590.9 1650.7 1935.2 1990.3 2002.3 1746 1120.9 1770.1 1911.1 TRUE FALSE FALSE 2079.737342 1728.410307 1711.876394 1927.192655 1966.566972 1587.000409 1794.988061 1462.65725 1575.924459 1977.510583 1.051694671 0.874033405 0.865672431 0.974554914 0.994465966 0.802524357 0.907700862 0.739645726 0.796923401 1 10.9494697 -2.082845434 0.260534583 1.029758049 4.26E-12 0 0.097928294 15.58101723 0.323323125 0.037300854 6.428678723 0.00826332 2.082845434 -1.029758049 TYAGGTAS(ph)ATK ddPTM_HeLa_Curcumin_4h_R1 1 TYAGGTASATK 11 0 P20810-6;P20810-7;P20810-10;P20810-9;P20810-5;A0A0C4DGB5;F8W7E0;E9PSG1;H0YA91;H0Y944;D6RBR1;D6RGF7;E7EN75 P20810-6 CAST Calpastatin 1 0 T(0.012)YAGGT(0.191)AS(0.794)AT(0.002)K 98.368 0.012086 18357000 2539.8 2072.9 2907.9 2240.8 2306.7 3990.2 3504.6 1668.1 2635.3 2266.5 TRUE FALSE FALSE 2338.77215 2252.072239 3015.669332 2231.528163 2279.194109 3162.587541 3602.929644 2176.696011 2346.214183 2345.260706 0.997233333 0.960265199 1.28585676 0.951505373 0.971829743 1.348501483 1.536259757 0.928125391 1.000406555 1 11.19553259 -5.26268661 24.99486598 1.0126192 1.297491975 0.30947821 0.1671488 80.86748511 1620631.413 0.021706527 0.051207621 5.46E-06 5.26268661 0.284872774 TYEDMTLEELEDHEDEFNEEDER ddPTM_HeLa_Curcumin_4h_R1 2 TYEDMTLEELEDHEDEFNEEDER 23 0 Q9H2J4 Q9H2J4 PDCL3 Phosducin-like protein 3 0 0 ; ; 188.27 5.80E-12 11522300 2537.3 2174.62 2678.9 2676.7 2807.3 2791.9 2596.2 2296.54 2645.1 2188.7 FALSE FALSE TRUE 2336.470028 2362.584463 2778.182391 2665.624525 2773.824781 2212.828469 2669.042385 2996.744474 2354.939148 2264.757162 1.031664704 1.043195492 1.226702111 1.17700236 1.224778015 0.977070966 1.178511511 1.323207858 1.039819715 1 11.14514065 -6.863947369 5.560151306 1.016174175 1.175996835 0.461220681 0.082144715 0.138844511 6.451127555 0.01313337 0.017383784 1.37E-07 6.863947369 0.15982266 TYEEGLK(ac)HEANNPQLK ddPTM_HeLa_Curcumin_4h_R1 1 TYEEGLKHEANNPQLK 16 1 P31948;P31948-2;F5H783;F5GXD8 P31948 STIP1 Stress-induced-phosphoprotein 1 0 1 TYEEGLK(1)HEANNPQLK 134.02 3.97E-11 0 1256.2 1579.7 1134.9 1179.2 2034.5 2694 1810.3 1803.7 2584.2 1141.6 FALSE TRUE FALSE 1156.770444 1716.242229 1176.960392 1174.320783 2010.239916 2135.234032 1861.092146 2353.639827 2300.719725 1181.270515 0.97925956 1.452878242 0.996351282 0.994116731 1.70176085 1.807574138 1.57550038 1.992464721 1.947665413 1 10.20612367 -5.7388757 6.176128142 1.028787086 1.763600908 0.292858865 0.33493293 0.051045396 6.380823113 0.024078016 0.047403977 1.82E-06 5.7388757 0.734813822 TYGCVPVANK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 TYGCVPVANKR 11 1 I3L0X5;O75391 I3L0X5 SPAG7 Sperm-associated antigen 7 0 1 ; TYGCVPVANK(1)R;TYGCVPVANK(1)R 123.86 0.0005387 6803200 2512.01 1261.9 2406.44 1363.59 1812.05 2446.61 1556.23 1500.43 1679.84 2237.65 FALSE TRUE FALSE 2313.181758 1370.973013 2495.624783 1357.947826 1790.442487 1939.155507 1599.893625 1957.9042 1495.565755 2315.408171 0.999038436 0.592108567 1.077833625 0.586483128 0.773272942 0.837500503 0.690976928 0.845597862 0.645918838 1 11.17705083 -7.306905873 22.41374663 0.999546108 0.776053406 0 0.173710831 89.40275335 44072.81142 0.020169033 0.023064294 4.93E-08 7.306905873 -0.223492702 TYGEHK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 TYGEHKR 7 1 Q9NR45 Q9NR45 NANS Sialic acid synthase 0 1 TYGEHK(1)R 73.665 0.016042 425210 391.57 343.85 325.05 0 433.16 565.94 218.3 348.05 343.09 374.53 FALSE TRUE FALSE 360.5768213 373.5708618 337.0966389 0 427.9948499 448.5576645 224.4249105 454.1688428 305.4538854 387.5448896 0.930413046 0.96394217 0.869826046 0 1.104374903 1.157434085 0.579093975 1.171912867 0.788176786 1 8.598219618 -6.525161247 24.75096293 0.963643592 0.787458882 0.020494098 0.32891404 148.5919553 1611288.97 0.049442031 0.070186495 2.98E-07 6.525161247 -0.17618471 TYGGDT(ph)GSPEISFTK ddPTM_HeLa_Curcumin_4h_R1 2 TYGGDTGSPEISFTK 15 0 O94915;H0Y9X0;A0A286YEZ9;A0A2C9F2R7 O94915 FRYL Protein furry homolog-like 1 0 T(0.056)Y(0.008)GGDT(0.629)GS(0.254)PEIS(0.05)FT(0.003)K;T(0.001)YGGDT(0.822)GS(0.157)PEIS(0.02)FTK ; 143.05 0.0014806 62842000 7357.7 5368.6 6035.6 6413.6 5968.6 9356.9 8404.5 9628.5 7435.7 6819.2 TRUE FALSE FALSE 6775.330281 5832.637862 6259.284645 6387.062223 5897.428343 7416.173466 8640.30765 12564.18533 6620.022313 7056.166692 0.960199862 0.826601484 0.88706587 0.905174509 0.835783592 1.051020163 1.224504469 1.780596445 0.938189615 1 12.78466893 -4.234674859 1.614050306 0.94790382 2.123882087 0.944815929 0.063460473 0.209413311 0.485001758 0.010827376 0.392311521 5.83E-05 4.234674859 1.175978267 TYGGDTGSPEISFT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 TYGGDTGSPEISFTK 15 0 O94915;H0Y9X0;A0A286YEZ9;A0A2C9F2R7 O94915 FRYL Protein furry homolog-like 1 0 T(0.245)YGGDT(0.107)GS(0.025)PEIS(0.025)FT(0.598)K 171.11 0.00045608 20080000 2607.6 2205.1 2152.2 2441.8 2372.2 3020.7 3001.9 2694.6 2413.6 2265.9 TRUE FALSE FALSE 2401.205708 2395.699018 2231.962425 2431.696479 2343.913064 2394.17277 3086.125235 3516.171136 2148.834119 2344.639856 1.024125604 1.021776974 0.951942542 1.037130062 0.99969002 1.021126022 1.316247025 1.499663637 0.916487926 1 11.19515062 -4.609397495 2.536778922 1.008125412 1.492987404 0.951730238 0.038035845 0.029451101 0.346164553 0.003533261 0.022028595 2.46E-05 4.609397495 0.484861992 TYLEEELDKWAK ddPTM_HeLa_Curcumin_4h_R1 2 TYLEEELDKWAK 12 1 A0A087X297;Q16719-2;Q16719;B8ZZA3;A0A087WYM2 A0A087X297 KYNU Kynureninase 0 0 ; ; 100.93 0.0075703 30344000 2686.7 2514.4 2691.9 2812.4 2183.1 3605.4 2700.4 3227 2843.2 3084.8 FALSE FALSE TRUE 2474.04486 2731.733532 2791.664182 2800.763034 2157.067958 2857.599399 2776.165956 4210.897445 2531.308073 3191.99657 0.775077543 0.855807164 0.87458245 0.877432971 0.675773896 0.895238869 0.869727111 1.319204878 0.793017166 1 11.64024339 -4.261320077 24.99999939 0.871265304 1.319205006 0.7336699 0.08427898 4.712516132 986355.2589 0.014054849 0.108849802 5.48E-05 4.261320077 0.447939702 TYS(ph)DEANQMR ddPTM_HeLa_Curcumin_4h_R1 1 TYSDEANQMR 10 0 A0A1B0GTL5;Q9BXF6 A0A1B0GTL5 RAB11FIP5 Rab11 family-interacting protein 5 1 0 T(0.266)YS(0.734)DEANQMR 167.84 0.00052653 45776000 3510.5 2744.9 2732.3 2732.9 2954.1 3688.1 2473.2 1937.5 3506.2 2733.1 TRUE FALSE FALSE 3232.640221 2982.156925 2833.561442 2721.591984 2918.874287 2923.146487 2542.591336 2528.234831 3121.578632 2828.075022 1.143053206 1.054482962 1.001939984 0.962347874 1.032106385 1.033617024 0.899053708 0.893977285 1.103782116 1 11.46560468 -4.161623492 0.550315993 1.06284527 0.735635539 0.569625212 0.049819442 2.83341356 0.534910537 0.012660974 0.606072355 6.89E-05 4.161623492 -0.32720973 TYS(ph)FEQPWPNAR ddPTM_HeLa_Curcumin_4h_R1 1 TYSFEQPWPNAR 12 0 Q5VWV2;Q8TEW0-4;Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-3;Q8TEW0-7;Q8TEW0-6;Q8TEW0-5 Q5VWV2 PARD3 Partitioning defective 3 homolog 1 0 T(0.233)Y(0.002)S(0.765)FEQPWPNAR 92.792 0.013331 5996500 587.07 729.99 520.53 857.66 816.11 1002.8 856.35 215.85 818.88 596.88 TRUE FALSE FALSE 540.60279 793.0870828 539.8212997 854.1112302 806.3784213 794.8079761 880.3768763 281.6616713 729.0509127 617.6215356 0.87529783 1.284098816 0.874032508 1.3829039 1.305619016 1.28688514 1.425430989 0.456042504 1.180416923 1 9.270579248 -7.269682338 24.86262058 0.941112862 1.166150392 0.014998428 0.285797229 842.396221 2540853.463 0.043918765 0.050673789 5.37E-08 7.269682338 0.22503753 TYS(ph)LTTPAR ddPTM_HeLa_Curcumin_4h_R1 3 TYSLTTPAR 9 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 T(0.007)YS(0.991)LT(0.002)TPAR;T(0.001)YS(0.996)LT(0.003)TPAR;T(0.049)YS(0.938)LT(0.013)TPAR ;; 123.11 0.0054294 338497000 9328.2 6914.5 7366.1 7735.4 7953.3 9060.6 7515.6 3436.73 8527.9 7908.9 TRUE FALSE FALSE 8589.863127 7512.15857 7639.094146 7703.392964 7858.462092 7181.329426 7726.467509 4484.573156 7592.410706 8183.733686 1.049626424 0.917937809 0.933448526 0.941305431 0.960253888 0.8775126 0.944124993 0.547986204 0.927744108 1 12.99854348 -3.877696885 1.177887903 0.997530901 4.61E-52 0.776584269 0.060771056 1.092694957 0.679075712 0.009439009 1.660551637 0.000132527 3.877696885 -0.997530901 EVSS(ph)RPSTPGLS(ph)VVSGISATSEDIPNKIEDLR ddPTM_HeLa_Curcumin_4h_R1 1 EVSSRPSTPGLSVVSGISATSEDIPNKIEDLR 32 2 Q14C86-4;Q14C86-5;Q14C86-2;Q14C86;Q14C86-6;F8W9S7;Q14C86-3;H0Y4E7;H0Y7I9;C9IZ08 Q14C86-4 GAPVD1 GTPase-activating protein and VPS9 domain-containing protein 1 2 0 EVS(0.467)S(0.486)RPS(0.217)T(0.217)PGLS(0.445)VVS(0.121)GIS(0.019)AT(0.02)S(0.007)EDIPNKIEDLR 42.799 0.01203 56932000 586.07 487.03 460.46 494.98 417.95 524.7 338.07 193.07 444.5 497.88 TRUE FALSE FALSE 539.6819411 529.126703 477.5250527 492.9319039 412.9662192 415.8713054 347.5553343 251.9361542 395.7394621 515.1812929 1.047557333 1.027068937 0.926906817 0.956812506 0.801593973 0.807232932 0.674627241 0.489024267 0.76815573 1 9.008936398 -4.025655153 0.495076989 1.026971653 9.06E-17 0.719453609 0.088967465 0.717703904 0.100262727 0.008019118 0.449767436 9.43E-05 4.025655153 -1.026971653 down SEMTAS(ph)PLVGPER ddPTM_HeLa_Curcumin_4h_R1 2 SEMTASPLVGPER 13 0 B4DIB3;A0A087X0I6;Q9P0L2-2;Q9P0L2-3;Q9P0L2 B4DIB3 MARK1 Serine/threonine-protein kinase MARK1 1 0 SEMT(0.112)AS(0.888)PLVGPER;SEMT(0.044)AS(0.956)PLVGPER ; 144.8 0.00078194 18148100 2828.7 2154 2343.84 2341.13 2326.16 2696.62 1837.52 831.87 3101.7 2528.51 TRUE FALSE FALSE 2604.80541 2340.182162 2430.704772 2331.443024 2298.422061 2137.310615 1889.075866 1085.503334 2761.45127 2616.375534 0.995577804 0.894436648 0.929035125 0.891096478 0.878475598 0.816897493 0.722020154 0.414888199 1.055449126 1 11.35335391 -4.025556524 0.611080096 0.987287794 2.49E-31 0.923429728 0.048124427 0.732725616 0.153304284 0.008075418 0.540856594 9.43E-05 4.025556524 -0.987287794 down YFDNKDDDS(ph)DTETSNDLPK ddPTM_HeLa_Curcumin_4h_R1 1 YFDNKDDDSDTETSNDLPK 19 1 C9J3R1;C9IZP0;J3KR59;J3KR68;Q9UID6 C9J3R1 ZNF639 Zinc finger protein 639 1 0 Y(0.005)FDNKDDDS(0.572)DT(0.299)ET(0.092)S(0.032)NDLPK 67.136 0.005309 25307000 3556.9 3252.2 3397.7 3139.1 3361.2 3972.9 2454.3 1290 3824.9 3422.4 TRUE FALSE FALSE 3275.367612 3533.305676 3523.621751 3126.111236 3321.119885 3148.875756 2523.161053 1683.315062 3405.318039 3541.328145 0.924898083 0.997734616 0.99500007 0.882751077 0.937817607 0.889179321 0.712490046 0.475334392 0.961593476 1 11.79007482 -4.024021758 0.933142662 0.965507753 3.73E-12 0.955553214 0.033023051 0.467443901 0.229070142 0.005909749 0.505556556 9.46E-05 4.024021758 -0.965507753 down TSS(ph)ISGPLSPAYTGQVPYNYNQLEGR ddPTM_HeLa_Curcumin_4h_R1 1 TSSISGPLSPAYTGQVPYNYNQLEGR 26 0 Q01082-3 Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 T(0.137)S(0.137)S(0.588)IS(0.137)GPLSPAYTGQVPYNYNQLEGR 151.35 4.40E-09 17424000 544.61 417.37 614.93 498.22 609.73 744.24 922.12 1058.4 449.28 413.06 TRUE FALSE FALSE 501.5035438 453.445603 637.7198467 496.1584977 602.459368 589.8762347 947.9922054 1381.101288 399.995108 427.4138043 1.173344283 1.060905377 1.492043168 1.16083873 1.409545883 1.380105717 2.217972831 3.231297805 0.935849764 1 8.739489693 -1 0.615877456 1.096059389 157.0073162 0.94840685 0.152674034 23.10216513 0.156083527 0.025304292 4882.310391 0.1 1 155.9112568 up TYSS(ph)PGSFK ddPTM_HeLa_Curcumin_4h_R1 1 TYSSPGSFK 9 0 Q8N3Z6 Q8N3Z6 ZCCHC7 Zinc finger CCHC domain-containing protein 7 1 0 T(0.004)YS(0.073)S(0.921)PGS(0.003)FK 139.38 0.0024445 23849000 5855.9 4760 5814.6 5485.3 5696.5 7935.1 5302 2570.9 6711.1 5424.5 TRUE FALSE FALSE 5392.399336 5171.43319 6030.094191 5462.603282 5628.572958 6289.270813 5450.75985 3354.755575 5974.90912 5613.000971 0.960698094 0.921331248 1.074308418 0.973205476 1.002774271 1.120482759 0.971095476 0.59767593 1.064476766 1 12.45455659 -4.26502074 5.432029394 0.993468653 0.583434437 0.813567214 0.05880719 0.042671561 4.702630301 0.007475917 0.064788614 5.43E-05 4.26502074 -0.410034216 TYSVEYLPK ddPTM_HeLa_Curcumin_4h_R1 2 TYSVEYLPK 9 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 157.91 4.01E-08 10995700 7638.6 6254.6 6069.6 6636.9 7044 9122.8 7064.9 6803.8 7326.5 6743.1 FALSE FALSE TRUE 7033.99675 6795.219754 6294.544715 6609.438266 6960.004901 7230.628445 7263.12208 8878.247299 6522.80128 6977.422223 1.008108227 0.973886851 0.902130402 0.947260758 0.99750376 1.036289365 1.040946333 1.272425119 0.934843997 1 12.76847842 -3.698233973 1.282184584 0.990006737 1.966031258 0.840680189 0.038550876 1.517575886 0.771312926 0.005763069 2.777556602 0.000200339 3.698233973 0.976024521 TYT(ph)HEVVTLWYR ddPTM_HeLa_Curcumin_4h_R1 1 TYTHEVVTLWYR 12 0 G3V5T9;P24941;Q00526;K7EJ83 G3V5T9 CDK2;CDK3 Cyclin-dependent kinase 2;Cyclin-dependent kinase 3 1 0 T(0.177)YT(0.823)HEVVTLWYR 91.845 0.013169 11801000 2567.6 2412.2 2577 1889.6 2136.7 4973.2 3153.9 2864.3 2347.1 2554.8 TRUE FALSE FALSE 2364.371751 2620.699819 2672.505887 1881.781336 2111.221248 3941.70226 3242.389946 3737.611884 2089.629002 2643.57911 0.894382824 0.991345335 1.010942278 0.711830915 0.798622307 1.49104759 1.226515194 1.413845294 0.790454499 1 11.36827679 -5.261259687 24.9999889 0.92983138 1.362073953 0.780921043 0.117643458 5.764716794 801947.4236 0.016014789 0.038184981 5.48E-06 5.261259687 0.432242573 NVAEALGHS(ph)PKDPGGGGGPVR ddPTM_HeLa_Curcumin_4h_R1 1 NVAEALGHSPKDPGGGGGPVR 21 1 Q8IU81 Q8IU81 IRF2BP1 Interferon regulatory factor 2-binding protein 1 1 0 NVAEALGHS(1)PKDPGGGGGPVR 59.585 0.0047004 60319000 3339.8 2668.6 2679.3 3366.8 2624.3 3564.4 2587.2 1072.1 3247 2933.5 TRUE FALSE FALSE 3075.451306 2899.261893 2778.597215 3352.869074 2593.006936 2825.103261 2659.789869 1398.978355 2890.812224 3035.438907 1.013181751 0.95513762 0.915385649 1.104574718 0.854244482 0.930706678 0.876245561 0.460881737 0.952353947 1 11.56768942 -4.023314489 1.345878717 0.992868272 2.14E-25 0.838791662 0.065571369 0.564637244 0.587509147 0.008882058 0.886970465 9.48E-05 4.023314489 -0.992868272 down VAADLQLS(ph)T(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 1 VAADLQLSTPQK 12 0 Q9H582;Q9H582-2 Q9H582 ZNF644 Zinc finger protein 644 2 0 VAADLQLS(1)T(1)PQK 143.37 0.0044553 3724900 1135 799.61 1169.5 1152.3 1172.3 1253.9 1234.4 919.04 1059.5 992.63 TRUE FALSE FALSE 1045.163552 868.7247254 1212.842699 1147.532088 1158.321088 993.8270056 1269.033942 1199.251065 943.2755007 1027.123819 1.017563349 0.845783838 1.1808145 1.117228582 1.127732672 0.967582474 1.235521871 1.167581789 0.91836591 1 10.00439439 -6.728091469 24.99919579 0.996337173 1.128975072 0.509778963 0.08421818 142.579122 106883.884 0.012304245 0.017400206 1.87E-07 6.728091469 0.132637899 VAADLQLS(ph)TPQK ddPTM_HeLa_Curcumin_4h_R1 1 VAADLQLSTPQK 12 0 Q9H582;Q9H582-2 Q9H582 ZNF644 Zinc finger protein 644 1 0 VAADLQLS(0.5)T(0.5)PQK 141.38 0.0011207 5983700 3557.5 3172.5 3322.6 3934.6 3685.7 5271.4 5704.5 1072.7 4518.5 3628 TRUE FALSE FALSE 3275.920121 3446.716764 3445.738479 3918.319668 3641.750435 4178.052219 5864.552917 1399.761292 4022.831855 3754.07273 0.872630968 0.918127328 0.917866735 1.043751666 0.970079883 1.112938539 1.56218415 0.372864724 1.071591347 1 11.87424089 -6.074559902 2.070531032 0.934863055 1.054436075 0 0.275910358 0.928875928 7.854782127 0.038984524 0.073450906 8.42E-07 6.074559902 0.11957302 VAADLQLST(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 1 VAADLQLSTPQK 12 0 Q9H582;Q9H582-2 Q9H582 ZNF644 Zinc finger protein 644 1 0 VAADLQLS(0.078)T(0.922)PQK 150.49 0.0015117 7278100 3664 2554.6 3052.4 3283.8 3087.7 5336.9 4463.1 1031.5 3759.7 2992.2 TRUE FALSE FALSE 3373.990534 2775.408241 3165.524629 3270.212506 3050.881194 4229.966781 4588.322574 1345.999602 3347.270316 3096.178727 1.089727316 0.896397943 1.022397254 1.056209216 0.985369858 1.366189472 1.481930786 0.434729297 1.081097253 1 11.59627304 STKPVVFS(ph)PTLMLTDEEK ddPTM_HeLa_Curcumin_4h_R1 1 STKPVVFSPTLMLTDEEK 18 1 P40818;P40818-2;A0A075B720 P40818 USP8 Ubiquitin carboxyl-terminal hydrolase 8 1 0 STKPVVFS(0.983)PT(0.012)LMLT(0.004)DEEK 84.327 0.0021307 20716000 2536 2156.4 2952.9 2615.8 2849.1 4012.7 3813.5 5016.3 2557.6 2159 TRUE FALSE FALSE 2335.272924 2342.789607 3062.337072 2604.976513 2815.126343 3180.420788 3920.496546 6545.746778 2277.037679 2234.025089 1.045320814 1.048685451 1.370771119 1.166046221 1.260114023 1.423628053 1.754902649 2.930023843 1.019253405 1 11.12542967 -1 0.654663445 1.047192275 173.0185555 0.965837585 0.102856225 25.10920382 0.147708362 0.018254659 6277.402073 0.1 1 171.9713632 up NFLNALTS(ph)PIEYQR ddPTM_HeLa_Curcumin_4h_R1 2 NFLNALTSPIEYQR 14 0 E7EPJ7;O75962-5;O75962-4;O75962;E7EWP2;O75962-2 E7EPJ7 TRIO Triple functional domain protein 1 0 NFLNALT(0.237)S(0.763)PIEYQR;NFLNALT(0.079)S(0.921)PIEYQR ; 176.43 0.00018427 39539000 4168.4 3544.3 3287.4 3449.3 3373.2 5888.1 4939.8 6321.2 3624.8 2549.6 TRUE FALSE FALSE 3838.466742 3850.653499 3409.233936 3435.027711 3332.976793 4666.841687 5078.397493 8248.504781 3227.168509 2638.19841 1.454957568 1.459576916 1.292258354 1.302035396 1.263353348 1.768950231 1.924949039 3.126567262 1.223247083 1 11.36533735 -1 0.669946646 1.234339062 194.8576771 0.937382604 0.14376351 48.65913467 0.270572359 0.032633369 14058.70814 0.1 1 193.623338 up VAAPQDGSPR ddPTM_HeLa_Curcumin_4h_R1 1 VAAPQDGSPR 10 0 Q9HD15 Q9HD15 SRA1 Steroid receptor RNA activator 1 0 0 100.25 0.010743 235660 195.65 212.18 212.06 158.6 163.48 244.86 122.48 112.66 169.6 167.09 FALSE FALSE TRUE 180.1640961 230.5198937 219.9191301 157.9437552 161.5306078 194.0732759 125.9164592 147.0095154 150.9953043 172.8963651 1.042035187 1.333283633 1.271970814 0.913516922 0.934262601 1.122483262 0.728277076 0.850275339 0.873328391 1 7.433763728 -4.760243839 24.99999852 1.052432487 0.789276153 0.362012136 0.144090465 24.628222 514935.0142 0.019573737 0.065874729 1.74E-05 4.760243839 -0.263156334 VAASGAQDPEKS(ph)PDRLK ddPTM_HeLa_Curcumin_4h_R1 1 VAASGAQDPEKSPDRLK 17 2 Q1MSJ5-2;Q1MSJ5-1;Q1MSJ5 Q1MSJ5-2 CSPP1 Centrosome and spindle pole-associated protein 1 1 0 VAASGAQDPEKS(1)PDRLK 76.574 0.0088597 10337000 3240 2393.2 2747.8 2701.1 3137.2 3584.8 2201.2 2064.2 3470.6 2624.3 TRUE FALSE FALSE 2983.550581 2600.057544 2849.635885 2689.923564 3099.790939 2841.272071 2262.959748 2693.565078 3089.883863 2715.49423 1.098713652 0.957489622 1.049398616 0.990583421 1.141519987 1.046318582 0.833350969 0.991924434 1.137871636 1 11.40699908 -4.784897216 24.88625674 1.044138736 0.912637724 0.400220782 0.0679537 133.7217295 141864.6252 0.008595405 0.025808325 1.64E-05 4.784897216 -0.131501012 VAASPKS(ph)PTAALNESLVECPK ddPTM_HeLa_Curcumin_4h_R1 2 VAASPKSPTAALNESLVECPK 21 1 Q53EZ4 Q53EZ4 CEP55 Centrosomal protein of 55 kDa 1 0 VAAS(0.02)PKS(0.526)PT(0.454)AALNES(0.001)LVECPK;VAASPKS(0.744)PT(0.256)AALNESLVECPK ; 92.147 0.00017976 49377000 4716.5 3061.1 3438.1 3598.7 2660.7 4690.2 4100 4516.9 5239.7 4186.2 TRUE FALSE FALSE 4343.184048 3325.687844 3565.51901 3583.809533 2628.97289 3717.399651 4215.034965 5894.082017 4664.918019 4331.670138 1.002658076 0.767761103 0.823128008 0.827350518 0.606918996 0.858190844 0.973073856 1.360695027 1.076932885 1 12.08070767 -4.26899438 3.985257153 0.923375437 1.397258944 0.512508298 0.135556097 0.173272852 5.688727791 0.021370857 0.234009508 5.38E-05 4.26899438 0.473883507 VAASVLNPYVK ddPTM_HeLa_Curcumin_4h_R1 1 VAASVLNPYVK 11 0 A0A494C0K9;H7C0C1;P48047 A0A494C0K9 ATP5O "ATP synthase subunit O, mitochondrial" 0 0 123.86 0.0015985 1275700 447.18 514.07 491.54 487.75 391.76 716.04 561.85 501.21 401.6 308.39 FALSE FALSE TRUE 411.7852311 558.5039201 509.7569048 485.7318197 387.0885179 567.5252326 577.6139989 654.0266217 357.5454848 319.1065295 1.290431856 1.750211508 1.597450562 1.522161958 1.213038537 1.778482043 1.810097712 2.049555748 1.120458065 1 8.317894319 -1.000000002 0.083877658 0.447777627 4.490818138 0.670962852 0.187362883 67.29462099 0.412942012 2.915168614 31.5796326 0.099999999 1.000000002 4.043040512 VAAYDK(ac)LEK ddPTM_HeLa_Curcumin_4h_R1 2 VAAYDKLEK 9 1 P35579 P35579 MYH9 Myosin-9 0 1 ; VAAYDK(1)LEK;VAAYDK(1)LEK 113.26 0.0025138 6977200 4150.3 4311.3 4059.3 3375.5 7929.9 8799 6870.5 5913.5 8732.6 4073.2 FALSE TRUE FALSE 3821.799376 4683.949561 4209.741229 3361.533075 7835.341122 6973.988215 7063.267739 7716.498928 7774.655628 4214.743397 0.906769171 1.111324966 0.998813174 0.797565299 1.859031591 1.65466496 1.675847632 1.83083481 1.844633207 1 12.04122908 -5.759334982 24.99999939 0.961564431 1.742260781 0.499439693 0.294714551 8.780520058 104309.0049 0.013594106 0.026154277 1.74E-06 5.759334982 0.78069635 VADAKGDS(ph)ES(ph)EEDEDLEVPVPSR ddPTM_HeLa_Curcumin_4h_R1 3 VADAKGDSESEEDEDLEVPVPSR 23 1 P13861-2;P13861 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 2 0 VADAKGDS(1)ES(1)EEDEDLEVPVPSR;VADAKGDS(1)ES(1)EEDEDLEVPVPSR;VADAKGDS(1)ES(1)EEDEDLEVPVPSR ;; 90.78 0.00012962 1650551000 35774 29808.1 29841.8 31729.7 30375.7 33571.8 26323.1 24028.6 37726 30125.1 TRUE FALSE FALSE 32942.45015 32384.57934 30947.76336 31598.41091 30013.48962 26608.63025 27061.65534 31354.80953 33587.55219 31171.94498 1.056798033 1.038901466 0.992808225 1.013681082 0.962836603 0.853608277 0.86814138 1.005866318 1.077492989 1 14.92796055 -5.601762692 3.049319131 1.02508705 0.90493122 0.592560279 0.044922542 0.127159537 2.379557296 0.006340966 0.013861073 2.50E-06 5.601762692 -0.120155831 VADAKGDS(ph)ESEEDEDLEVPVPSR ddPTM_HeLa_Curcumin_4h_R1 2 VADAKGDSESEEDEDLEVPVPSR 23 1 P13861-2;P13861 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 1 0 VADAKGDS(0.919)ES(0.081)EEDEDLEVPVPSR;VADAKGDS(0.995)ES(0.005)EEDEDLEVPVPSR ; 95.591 5.18E-05 52410000 3263.3 2545.3 2913.5 3032.4 2883.1 4592.9 3060 3748.3 3604.5 2682.9 TRUE FALSE FALSE 3005.006362 2765.30439 3021.476873 3019.852732 2848.720916 3640.280767 3145.855364 4891.139415 3209.095368 2776.130575 1.082444172 0.996100261 1.088377074 1.087792037 1.026148028 1.311278655 1.133179899 1.761854957 1.155959808 1 11.43885971 -1.043205297 0.832653778 1.043706903 200 0.832694542 0.088901914 123.7510095 0.38227515 0.011756836 46556.9958 0.090530455 1.043205297 198.9562931 VADAKGDSES(ph)EEDEDLEVPVPSR ddPTM_HeLa_Curcumin_4h_R1 1 VADAKGDSESEEDEDLEVPVPSR 23 1 P13861-2;P13861 P13861-2 PRKAR2A cAMP-dependent protein kinase type II-alpha regulatory subunit 1 0 VADAKGDS(0.006)ES(0.994)EEDEDLEVPVPSR 84.169 0.00017759 72177000 918.47 551.51 622.35 741.65 790.26 1070.4 868.77 661.64 801.7 715.16 TRUE FALSE FALSE 845.7721303 599.1800669 645.4148385 738.5812488 780.8366656 848.3869741 893.145348 863.3709902 713.7555158 740.0117568 1.142917153 0.809689929 0.872168358 0.998066912 1.055167919 1.14645067 1.206933998 1.166699018 0.964519157 1 9.531404381 -5.226525944 2.783238149 1.026995963 1.185370368 0.416113895 0.095500115 0.292427643 4.470747394 0.016525211 0.046738901 5.94E-06 5.226525944 0.158374406 VADISGDTQK ddPTM_HeLa_Curcumin_4h_R1 2 VADISGDTQK 10 0 Q7KZF4;H7C597 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 0 ; ; 142.92 1.84E-05 7227300 6627.7 5397.2 5631.7 6170.5 6381.8 6955.7 4899.6 4759.1 6046 5826.4 FALSE FALSE TRUE 6103.110551 5863.709919 5840.415756 6144.968106 6305.701203 5513.009413 5037.069589 6210.127682 5382.768926 6028.866966 1.012314683 0.972605624 0.968741853 1.019257539 1.04591812 0.914435406 0.835491912 1.030065469 0.892832593 1 12.55767118 -5.244037621 24.24601043 1.003881513 0.917547008 0.134216905 0.060031366 399.5792613 556735.272 0.006223088 0.015817702 5.70E-06 5.244037621 -0.086334505 VSAEAEVAPVSPEVT(ph)QEVVEEHCASPEDK ddPTM_HeLa_Curcumin_4h_R1 2 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 VSAEAEVAPVS(0.021)PEVT(0.493)QEVVEEHCAS(0.486)PEDK;VSAEAEVAPVS(0.004)PEVT(0.962)QEVVEEHCAS(0.034)PEDK ; 87.952 2.24E-06 402270000 3770 3972 4004.5 3803.6 5213.2 5832.9 5191.5 6678.9 3674.4 3561.5 TRUE FALSE FALSE 3471.600522 4315.321981 4152.910293 3787.861711 5151.035995 4623.09079 5337.159518 8715.265864 3271.327513 3685.26186 0.942022753 1.170967531 1.126896934 1.027840586 1.39773948 1.254480947 1.44824431 2.364897311 0.887678444 1 11.84755142 -1 0.595878429 0.999142178 81.02370303 0.908424278 0.123371405 28.80065325 0.208134423 0.021017418 3006.498824 0.1 1 80.02456085 up KAEGAATEEEGT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 KAEGAATEEEGTPK 14 1 P80723;P80723-2;U3KQP0 P80723 BASP1 Brain acid soluble protein 1 1 0 KAEGAATEEEGT(1)PK;KAEGAATEEEGT(1)PK ; 117.3 0.0010546 55874000 11601.8 9330.7 11018.4 12147.8 13811.6 15617.7 15461.4 16972.5 12531.3 10256.2 TRUE FALSE FALSE 10683.50529 10137.20413 11426.7516 12097.53562 13646.90569 12378.41297 15895.20527 22147.33712 11156.64774 10612.60219 1.006681029 0.955204384 1.076715342 1.139921709 1.285915127 1.166388107 1.497766994 2.086890353 1.051264105 1 13.37349082 -1 0.572976753 1.005200948 57.58223806 0.95402755 0.069638105 17.66356401 0.137484636 0.012278139 1244.93621 0.1 1 56.57703711 up VADPDHDHTGFLTEYVATR ddPTM_HeLa_Curcumin_4h_R1 2 VADPDHDHTGFLTEYVATR 19 0 P28482-2;P28482 P28482-2 MAPK1 Mitogen-activated protein kinase 1 0 0 ; ; 105.06 0.00019746 16816900 10987 9014.2 9213.3 9473.8 10217.8 11461.7 8521.3 7673.5 11116 10342.1 FALSE FALSE TRUE 10117.36736 9793.347282 9554.753003 9434.599926 10095.95941 9084.41422 8760.384744 10013.11483 9896.602611 10701.48721 0.945416947 0.915138905 0.892843473 0.881615774 0.943416482 0.848892686 0.818613766 0.935675073 0.924787595 1 13.38552368 -7.507606224 0.409691203 1.002814761 0.867336165 0.311153672 0.041128874 0.448003696 0.205102367 0.020878292 0.019366919 3.11E-08 7.507606224 -0.135478596 VAEIEHAEK ddPTM_HeLa_Curcumin_4h_R1 2 VAEIEHAEK 9 0 F5GWF6;P78371;F8VQ14;P78371-2 F5GWF6 CCT2 T-complex protein 1 subunit beta 0 0 ; ; 106.88 0.0048803 10909700 11497.6 9493.3 11024.8 10834.2 12682.8 12986.3 10477.1 9707.1 9651.8 10139.4 FALSE FALSE TRUE 10587.55283 10313.85855 11433.38879 10789.37095 12531.56589 10292.79499 10771.05923 12666.7501 8593.021688 10491.7434 1.009131889 0.983045254 1.089751089 1.028367788 1.194421692 0.981037622 1.026622442 1.20730651 0.819027054 1 13.35696681 -6.755955819 24.9873866 1.002837743 1.082407781 0.299223741 0.088732605 135.6423168 618089.2426 0.009871927 0.01373083 1.75E-07 6.755955819 0.079570038 VAEIEHAEK(ac)EK ddPTM_HeLa_Curcumin_4h_R1 1 VAEIEHAEKEK 11 1 F5GWF6;P78371;F8VQ14;P78371-2 F5GWF6 CCT2 T-complex protein 1 subunit beta 0 1 VAEIEHAEK(1)EK 51.727 0.019622 0 3211.1 4624.1 2806.9 3440.8 4252 6229.9 4604.4 4515.8 7009.6 3760.8 FALSE TRUE FALSE 2956.938047 5023.786599 2910.926183 3426.562881 4201.297677 4937.748515 4733.587072 5892.646632 6240.664417 3891.48752 0.759847753 1.29096819 0.748024031 0.880527784 1.07961227 1.268858885 1.216395285 1.514240146 1.603670675 1 11.92610602 -4.929379442 0.898901194 0.902554639 1.517665499 0.072449571 0.270502374 0.534255252 0.569497187 0.026125031 0.256184556 1.18E-05 4.929379442 0.61511086 VAEIEHAEKEK ddPTM_HeLa_Curcumin_4h_R1 2 VAEIEHAEKEK 11 1 F5GWF6;P78371;F8VQ14;P78371-2 F5GWF6 CCT2 T-complex protein 1 subunit beta 0 0 ; ; 72.2 0.017246 11816000 12154.3 9955.7 9958.2 10546.4 9729.6 13287.8 10040.4 9629.4 14144.4 11267.5 FALSE FALSE TRUE 11192.27433 10816.22635 10327.25965 10502.76179 9613.580875 10531.7605 10322.1066 12565.35973 12592.79471 11659.04479 0.959964949 0.927711193 0.885772363 0.900825238 0.824559906 0.903312466 0.885330384 1.077734923 1.080088029 1 13.50916197 -7.497467501 1.277965086 0.987498399 0.906721441 0.287439876 0.067886556 0.411815735 1.340482171 0.012651736 0.013539825 3.18E-08 7.497467501 -0.080776958 VAEK(ac)LEALSVK ddPTM_HeLa_Curcumin_4h_R1 1 VAEKLEALSVK 11 1 P43487-2;P43487;F6WQW2;C9JXG8 P43487-2 RANBP1 Ran-specific GTPase-activating protein 0 1 VAEK(1)LEALSVK 116.24 0.0025489 538000 213.75 0 234.32 182.63 164.84 411.59 194.39 176.18 329.2 0 FALSE TRUE FALSE 196.831462 0 243.0041053 181.8743255 162.8743907 326.2215944 199.8440602 229.896471 293.0875836 0 0 VAEKLDEIYVAGLVAHSDLDER ddPTM_HeLa_Curcumin_4h_R1 2 VAEKLDEIYVAGLVAHSDLDER 22 1 O60506-4;O60506-3;O60506-2;O60506;F6UXX1 O60506-4 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0 0 ; ; 163.78 2.63E-08 41106000 8004.1 6660.4 6675.7 8011.2 6581.8 8834.7 6811.7 6802.1 8181.6 6931 FALSE FALSE TRUE 7370.567039 7236.095298 6923.107315 7978.051777 6503.316334 7002.283632 7002.817969 8876.028977 7284.098949 7171.851734 1.027707671 1.008957737 0.96531657 1.1124117 0.906783433 0.976356441 0.976430945 1.237620256 1.015651079 1 12.80812995 -4.257086537 24.75082857 1.005122239 1.237620363 0.670173901 0.05007855 165.8147249 942802.6737 0.006422908 0.066797919 5.53E-05 4.257086537 0.232498123 VAELALSLSST(ph)SDDEPPSSVSHGAK ddPTM_HeLa_Curcumin_4h_R1 2 VAELALSLSSTSDDEPPSSVSHGAK 25 0 Q5T7F5;Q8N1G2 Q5T7F5 CMTR1 Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 1 0 VAELALS(0.001)LS(0.003)S(0.081)T(0.511)S(0.404)DDEPPSSVSHGAK;VAELALS(0.001)LS(0.003)S(0.021)T(0.583)S(0.393)DDEPPSSVSHGAK ; 151.19 1.53E-08 34703000 2804.9 2599.4 2034.44 2350.75 4624.2 8998.1 3445.4 2118.7 4728.9 2609.9 TRUE FALSE FALSE 2582.889205 2824.080553 2109.838136 2341.023219 4569.059435 7131.792631 3542.068651 2764.681877 4210.151501 2700.593831 0.95641528 1.045725766 0.781249706 0.866854983 1.691872129 2.640823862 1.311588811 1.023731094 1.558972495 1 11.39906096 -5.756080316 24.67829501 0.960915442 1.711175953 0.325350912 0.436395269 77.77735352 358157.0175 0.056871206 0.111108066 1.75E-06 5.756080316 0.750260511 VAELLLLHGAEPNCADPATLTRPVHDAAR ddPTM_HeLa_Curcumin_4h_R1 1 VAELLLLHGAEPNCADPATLTRPVHDAAR 29 1 J3QRG6;P42771;P42771-4;K7ES20;K7ENC6;P42771-2;P42772 J3QRG6 CDKN2A;CDKN2B Cyclin-dependent kinase inhibitor 2A;Cyclin-dependent kinase 4 inhibitor B 0 0 26.039 0.020398 14091000 1153.5 968.05 824.56 1141.7 1229.8 1645.8 973.77 870.72 1345.3 883.71 FALSE FALSE TRUE 1062.199258 1051.723928 855.118919 1136.975948 1215.135438 1304.442528 1001.091365 1136.19852 1197.723956 914.4188567 1.161611279 1.150155556 0.935150137 1.243386375 1.328860871 1.426526278 1.094784253 1.242536187 1.309819835 1 9.836711344 -6.098997719 7.779990374 1.075489203 1.273180856 0.264764792 0.123574275 0.204344492 14.330072 0.016242175 0.027022428 7.96E-07 6.098997719 0.197691653 VAEPGAEAT(ph)SSTGEESGSEHPPAVPMHNK ddPTM_HeLa_Curcumin_4h_R1 1 VAEPGAEATSSTGEESGSEHPPAVPMHNK 29 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 0 VAEPGAEAT(0.348)S(0.307)S(0.272)T(0.052)GEES(0.011)GS(0.011)EHPPAVPMHNK 65.213 0.00015126 8126500 1975 1456.2 1751 1415.4 3187.5 4081.7 2046.3 1128.6 2064.6 1341.9 TRUE FALSE FALSE 1818.676666 1582.067439 1815.8936 1409.54345 3149.491144 3235.10941 2103.713671 1472.704945 1838.118545 1388.530925 1.309784775 1.139382214 1.307780452 1.015132918 2.268218221 2.329879264 1.515064326 1.060620918 1.323786537 1 10.43934359 -5.779712348 24.999928 1.154378608 1.811878077 0.415894982 0.353396001 171.2560314 234301.4742 0.054057559 0.098121186 1.66E-06 5.779712348 0.657499468 VAETMCY(ph)AY(ph)MK ddPTM_HeLa_Curcumin_4h_R1 1 VAETMCYAYMK 11 0 C9JFU6;C9JCB7;C9JE50;C9JW33;Q8NBZ7-3;Q8NBZ7;Q8NBZ7-2 C9JFU6 UXS1 UDP-glucuronic acid decarboxylase 1 2 0 VAET(0.008)MCY(0.993)AY(0.999)MK 78.264 0.020097 8542200 3045.7 4692.4 4470.2 3281.9 2622.7 3603.1 4256 2851.3 3417.5 5575.3 TRUE FALSE FALSE 2804.629631 5097.990147 4635.869544 3268.320367 2591.426015 2855.776445 4375.411906 3720.648244 3042.6088 5769.04126 0.486151772 0.883680653 0.803577117 0.566527473 0.449195265 0.495017511 0.758429643 0.644933547 0.52740285 1 12.49411587 -9.47056839 1.091020848 1.009789102 0.625070268 0 0.199195109 0.383853395 0.782865976 0.117717553 0.026088749 3.38E-10 9.47056839 -0.384718834 VAFQFPTK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VAFQFPTKK 9 1 Q96GN5-5;Q96GN5-2;Q96GN5;C9IZR6;Q96GN5-4 Q96GN5-5 CDCA7L Cell division cycle-associated 7-like protein 0 1 ; VAFQFPTK(1)K;VAFQFPTK(1)K 136.57 8.20E-05 3324300 2910.4 3142.4 3228.6 3162.5 3252.1 3959.6 2304.2 1632.24 3496.6 3197.6 FALSE TRUE FALSE 2680.038769 3414.015054 3348.254756 3149.414413 3213.320832 3138.334326 2368.849651 2129.902462 3113.031728 3308.716362 0.809993507 1.031824635 1.011949768 0.951853852 0.971168417 0.948505095 0.715942194 0.643724704 0.94085784 1 11.69205591 -4.6867098 4.156317086 0.934015259 0.661114155 0.759801793 0.061852735 0.107537724 3.485850575 0.011821092 0.048565381 2.06E-05 4.6867098 -0.272901104 VAGGAAPSK(ac)PASAK ddPTM_HeLa_Curcumin_4h_R1 2 VAGGAAPSKPASAK 14 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 1 ; VAGGAAPSK(1)PASAK;VAGGAAPSK(1)PASAK 182.23 5.76E-08 7580300 6945.6 6199 5558.4 6223.2 8136.3 9136.3 7285.4 7544.6 7961.2 6038.6 FALSE TRUE FALSE 6395.848431 6734.813938 5764.399194 6197.450047 8039.279936 7241.328393 7489.808716 9844.913809 7087.876278 6248.440901 1.02359109 1.077839103 0.922534003 0.991839428 1.286605741 1.158901638 1.19866841 1.575579247 1.134343173 1 12.60928054 -1.000000001 0.503943331 1.008028159 18.53800961 0.739925619 0.091400989 29.73134273 0.282588813 0.015692746 556.1846406 0.1 1.000000001 17.52998145 VAGGAAPSKPAS(ph)AK ddPTM_HeLa_Curcumin_4h_R1 1 VAGGAAPSKPASAK 14 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 1 0 VAGGAAPS(0.005)KPAS(0.995)AK 69.188 0.014977 384740000 4775.2 3871 4419.1 3964.8 4256.1 6710.3 7062 2672.6 4368.9 3029.2 TRUE FALSE FALSE 4397.237881 4205.591991 4582.875733 3948.394708 4205.348787 5318.508139 7260.140714 3487.463437 3889.6426 3134.464475 1.402867353 1.341725844 1.462092096 1.259671226 1.341648253 1.696783672 2.31623002 1.112618588 1.24092732 1 11.61400326 -8.679752067 0.07570077 1.08E-15 2.440329827 0.221853513 0.308461673 32.89921566 0.905646343 17.67354186 11.35285189 2.09E-09 8.679752067 2.440329827 VAGGAAPSKPASAK ddPTM_HeLa_Curcumin_4h_R1 1 VAGGAAPSKPASAK 14 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 0 108.68 0.00095231 3935200 3333.2 2726.5 2927.3 2910.2 2925.8 3163.7 2749.4 2895.5 3162.2 2884.6 FALSE FALSE TRUE 3069.373703 2962.166511 3035.788313 2898.158364 2890.911746 2507.512958 2826.540764 3778.324621 2815.314571 2984.839635 1.028321142 0.992403905 1.017069151 0.970959488 0.96853168 0.840082974 0.946965703 1.265838398 0.943204633 1 11.54343771 -6.274904794 22.87767585 1.012059173 0.985150839 0 0.103599295 1179.695005 2004295.888 0.015055734 0.023100652 5.31E-07 6.274904794 -0.026908335 VAGGAAPSKPASAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VAGGAAPSKPASAKK 15 2 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 1 ; VAGGAAPSKPASAK(1)K;VAGGAAPSKPASAK(1)K 152.88 0.00066767 94294000 14624.2 10213.6 12883.5 12030.3 13191.4 15387.6 13957 13915.2 13936.3 12183.7 FALSE TRUE FALSE 13466.67914 11096.41807 13360.97384 11980.52181 13034.10117 12196.03831 14348.59586 18157.88042 12407.52276 12607.08267 1.068183615 0.880173341 1.059799019 0.950300884 1.033871318 0.967395759 1.138137683 1.440292009 0.98417081 1 13.62194685 -4.317320006 2.600041051 1.014882167 1.500499407 0.850066826 0.05653442 0.115130265 1.080364896 0.007788721 0.114485287 4.82E-05 4.317320006 0.48561724 VAGPADAPMDS(ph)GAEEEKAGAATVK ddPTM_HeLa_Curcumin_4h_R1 1 VAGPADAPMDSGAEEEKAGAATVK 24 1 Q8TEK3;Q8TEK3-1 Q8TEK3 DOT1L "Histone-lysine N-methyltransferase, H3 lysine-79 specific" 1 0 VAGPADAPMDS(1)GAEEEKAGAATVK 72.916 0.0017853 47043000 3637.4 2799.7 3319.8 3404 3117.2 3984.3 3109.7 1278.9 4166.3 2993.3 TRUE FALSE FALSE 3349.495952 3041.693593 3442.834708 3389.91515 3080.029426 3157.911268 3196.949813 1668.830723 3709.267314 3097.316952 1.081418532 0.982041438 1.111553891 1.094468278 0.994418548 1.019563486 1.032167473 0.538798821 1.197574343 1 11.59680331 -4.261242733 6.805531535 1.03978676 0.530438562 0.850107723 0.064927463 0.022106394 7.062451067 0.006238918 0.051459812 5.48E-05 4.261242733 -0.509348198 VAGQDGSVVQFK ddPTM_HeLa_Curcumin_4h_R1 2 VAGQDGSVVQFK 12 0 A8MUA9;A8MU27;P55854;P55854-2;Q6EEV6;P61956-2;P61956 A8MUA9;P61956-2 SUMO3;SUMO4;SUMO2 Small ubiquitin-related modifier 3;Small ubiquitin-related modifier 4;Small ubiquitin-related modifier 2 0 0 ; ; 199.68 1.08E-14 18316900 7323.8 6375 6947.6 6550.3 5979.7 7480.6 6545.5 4374.6 7559.5 6299.1 FALSE FALSE TRUE 6744.113502 6926.026594 7205.084168 6523.196594 5908.395983 5929.039236 6729.149114 5708.395402 6730.241763 6517.993256 1.034691697 1.062601068 1.105414486 1.000798304 0.9064747 0.909641818 1.032395839 0.87579032 1.032563474 1 12.67021214 -5.921740819 5.875330737 1.028126059 0.937511322 0.55244268 0.047554231 0.148394399 8.565859311 0.00718383 0.013132607 1.20E-06 5.921740819 -0.090614738 VAIEHLDK ddPTM_HeLa_Curcumin_4h_R1 1 VAIEHLDK 8 0 E7ENZ3;B7ZAR1;E9PCA1;P48643-2;P48643 E7ENZ3 CCT5 T-complex protein 1 subunit epsilon 0 0 88.37 0.018332 29930000 9857.5 8160.3 8727.8 9041.4 9486.1 11000 8790.2 7598.2 8917 7698.5 FALSE FALSE TRUE 9077.268473 8865.63997 9051.259946 9003.989082 9372.984453 8718.476004 9036.829354 9914.856202 7938.827409 7966.022302 1.13949825 1.112931854 1.136233317 1.130299256 1.176620413 1.094457896 1.134421799 1.24464329 0.996586139 1 12.9596438 -13.52287875 0.190515081 0.335969135 1.17475209 0.744843942 0.035687773 20.4725963 0.24244575 5.026428596 0.041290044 3.00E-14 13.52287875 0.838782955 VALHLDEEDKLR ddPTM_HeLa_Curcumin_4h_R1 1 VALHLDEEDKLR 12 1 A0A087X297;Q16719-2;Q16719;B8ZZA3;F8WEP1 A0A087X297 KYNU Kynureninase 0 0 117.71 0.0017549 15737000 6932 5665.6 5594.8 5803.1 6609.6 7320.5 5707.9 4938.7 6897.3 6573.4 FALSE FALSE TRUE 6383.324885 6155.309219 5802.14821 5779.08831 6530.784837 5802.145781 5868.048312 6444.486895 6140.683446 6801.825161 0.938472356 0.904949638 0.853028132 0.84963788 0.960151824 0.853027775 0.862716723 0.947464356 0.902799367 1 12.73170621 -7.878981574 0.819346769 0.989251273 0.886135087 0.137821725 0.04661278 0.281433499 0.409695078 0.011432369 0.009230631 1.32E-08 7.878981574 -0.103116186 VALK(ac)GPQVDVK ddPTM_HeLa_Curcumin_4h_R1 2 VALKGPQVDVK 11 1 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 0 1 ; VALK(1)GPQVDVK;VALK(1)GPQVDVK 132.32 0.00068146 6016200 3748.4 3278.4 3412.5 4063.2 4373.5 4799.3 4476.5 4765.7 4941.9 3324 FALSE TRUE FALSE 3451.710185 3561.770288 3538.970252 4046.387555 4321.348869 3803.871081 4602.098542 6218.739991 4399.785934 3439.508753 1.003547435 1.03554622 1.028917356 1.176443453 1.256385484 1.105934409 1.338010418 1.808031448 1.279190213 1 11.74798681 -1 0.541028609 1.009724692 33.34317804 0.772954484 0.110973584 22.59146079 0.193769936 0.013591832 849.7814436 0.1 1 32.33345334 VALLPPVLK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 VALLPPVLKK 10 1 Q5VZK9;Q5VZK9-2;A0A0U1RQQ1 Q5VZK9 LRRC16A Leucine-rich repeat-containing protein 16A 0 1 VALLPPVLK(1)K 109.01 2.74E-05 0 499.32 578.45 558.49 418.33 414.49 705.15 520.27 845.26 523.28 547.32 FALSE TRUE FALSE 459.7982951 628.4486405 579.1881307 416.5990613 409.5474775 558.8939413 534.867376 1102.975883 465.8774932 566.3393293 0.811877741 1.109668017 1.022687461 0.735599736 0.723148572 0.986853486 0.944429158 1.947553041 0.822611938 1 9.145522911 -4.260185694 5.409999544 0.911275311 1.988208192 0.867339257 0.122218371 0.041306776 4.447712222 0.017787989 0.163999447 5.49E-05 4.260185694 1.076932881 VALS(ph)DDETK ddPTM_HeLa_Curcumin_4h_R1 1 VALSDDETK 9 0 H0YD46;Q15054-3;Q15054-2;Q15054 H0YD46 POLD3 DNA polymerase delta subunit 3 1 0 VALS(0.999)DDET(0.001)K 93.442 0.016975 32197000 2466.2 1951.9 2567.2 2407.1 2659.1 2920 2529.8 1794.9 2479.4 2357.4 TRUE FALSE FALSE 2270.997668 2120.613539 2662.34269 2397.140058 2627.391969 2314.359085 2600.779379 2342.156747 2207.416023 2439.319475 0.930996408 0.869346373 1.091428457 0.982708531 1.077100395 0.948772438 1.066190553 0.960168101 0.904931087 1 11.252263 -6.750336706 24.99996797 0.959149356 1.020630769 0.336331642 0.058309399 251.9485047 567312.8718 0.008745685 0.012301554 1.78E-07 6.750336706 0.061481413 VALS(ph)DDETKETENMR ddPTM_HeLa_Curcumin_4h_R1 4 VALSDDETKETENMR 15 1 H0YD46;Q15054-3;Q15054-2;Q15054 H0YD46 POLD3 DNA polymerase delta subunit 3 1 0 VALS(0.609)DDET(0.168)KET(0.223)ENMR;VALS(1)DDETKETENMR;VALS(1)DDETKETENMR;VALS(1)DDETKETENMR ;;; 223.7 4.67E-14 938916100 11090.4 8186.18 9616.5 9234.94 9512.7 10310.9 8397.22 6748.76 10212.5 8679.7 TRUE FALSE FALSE 10212.58314 8893.756922 9972.89595 9196.728265 9399.267265 8172.303112 8632.823393 8806.425857 9092.2143 8981.318929 1.137091692 0.990250652 1.110404388 1.023984154 1.046535296 0.909922382 0.961197733 0.980527017 1.012347337 1 13.13271161 -5.36729016 5.539806688 1.060283616 0.95205499 0.431318928 0.048288307 0.166027601 7.230244658 0.008284576 0.018817845 4.29E-06 5.36729016 -0.108228626 VALSDDET(ph)KETENMR ddPTM_HeLa_Curcumin_4h_R1 1 VALSDDETKETENMR 15 1 H0YD46;Q15054-3;Q15054-2;Q15054 H0YD46 POLD3 DNA polymerase delta subunit 3 1 0 VALS(0.011)DDET(0.976)KET(0.013)ENMR 83.869 0.019127 76618000 8213 6298.2 7500.4 7633.7 6848.6 8318.5 6706.9 6791.6 7883.1 7413.2 TRUE FALSE FALSE 7562.932384 6842.588344 7778.371422 7602.113772 6766.934918 6593.149331 6895.077563 8862.327575 7018.343653 7670.808148 0.985936845 0.892029655 1.014022417 0.991044702 0.882167144 0.859511697 0.898872378 1.155331668 0.914941883 1 12.90516286 -7.492517549 21.70358508 0.9937958 0.950090127 0 0.085415102 185.6415034 132709.3261 0.013820377 0.015116854 3.22E-08 7.492517549 -0.043705672 VALSS(ph)ETEVALAR ddPTM_HeLa_Curcumin_4h_R1 2 VALSSETEVALAR 13 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 VALS(0.023)S(0.955)ET(0.023)EVALAR;VALS(0.041)S(0.864)ET(0.095)EVALAR ; 198.52 1.73E-06 10944000 3447 2477.9 2957.1 3184 2659 3730.4 2649.3 2763.1 3136.1 2861.3 TRUE FALSE FALSE 3174.166313 2692.078635 3066.692727 3170.825452 2627.293162 2956.67299 2723.632228 3605.55647 2792.077676 2960.729962 1.072089097 0.909261793 1.035789406 1.070960706 0.887380205 0.998629739 0.919919163 1.217793084 0.943036924 1 11.5317372 VALVNDSLS(ph)DVTSTTSSR ddPTM_HeLa_Curcumin_4h_R1 1 VALVNDSLSDVTSTTSSR 18 0 Q7Z2W4-2;Q7Z2W4 Q7Z2W4-2 ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 1 0 VALVNDS(0.133)LS(0.812)DVT(0.055)S(0.001)TTSSR 198.67 1.48E-09 10656000 1735.3 2053.3 1533.8 1889.1 1838.2 3096.8 2659 1132 2014.5 1819.3 TRUE FALSE FALSE 1597.949174 2230.778103 1590.643977 1881.283405 1816.280666 2454.488772 2733.604384 1477.141589 1793.51439 1882.52054 0.848834921 1.184995359 0.844954381 0.999342831 0.9648132 1.303831071 1.452098039 0.784661605 0.952719693 1 10.87844989 -5.308386695 8.988344285 0.947761926 1.207232763 0.20696079 0.181710684 0.369150404 68.39622859 0.024332108 0.054650871 4.92E-06 5.308386695 0.259470837 VANPSGNLT(ph)ETYVQDR ddPTM_HeLa_Curcumin_4h_R1 1 VANPSGNLTETYVQDR 16 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 VANPS(0.024)GNLT(0.844)ET(0.133)YVQDR 111.7 0.0043464 4849400 1250.7 907.46 1177.7 1155.5 1217.6 1445.1 756.06 777.55 1241.2 1294.9 TRUE FALSE FALSE 1151.705775 985.8967988 1221.346598 1150.718847 1203.080915 1145.36997 777.2730088 1014.621416 1105.043465 1339.897679 0.859547556 0.735800065 0.911522288 0.858810986 0.897890141 0.854818983 0.58009878 0.757237983 0.824722278 1 10.38790712 -1.828161717 0.064901436 1.253631768 7.44E-12 0.195861828 0.097856317 142.2725595 0.809880365 3.397959547 17.22306668 0.014853824 1.828161717 -1.253631768 VANPSGNLTETYVQDR ddPTM_HeLa_Curcumin_4h_R1 2 VANPSGNLTETYVQDR 16 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 327.94 1.02E-177 25204000 1367.95 1096.26 1071.37 1496.88 1320.86 1520.66 1103.47 1296.86 1352.49 1342.48 FALSE FALSE TRUE 1259.675314 1191.01583 1111.075915 1490.686307 1305.109607 1205.257975 1134.430398 1692.266644 1204.125231 1389.13108 0.906808099 0.857381889 0.799835185 1.073107015 0.939515087 0.867634446 0.816647482 1.218219553 0.866819012 1 10.43996702 -4.246108018 24.21854313 0.932039714 1.218219877 0.539039375 0.083654101 1210.333466 1911884.029 0.011864941 0.365575056 5.67E-05 4.246108018 0.286180163 VAPAPAVVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VAPAPAVVKK 10 1 P62424;Q5T8U3 P62424 RPL7A 60S ribosomal protein L7a 0 1 ; VAPAPAVVK(1)K;VAPAPAVVK(1)K 136.16 0.00020713 13729300 9232.8 8842 8526.6 8197.2 8528.5 11512.1 7908.7 6692.8 10594.7 8460.1 FALSE TRUE FALSE 8502.014138 9606.263081 8842.603297 8163.282158 8426.803208 9124.360692 8130.596837 8733.40391 9432.487917 8754.087845 0.971205029 1.097345977 1.010111328 0.93251088 0.962613508 1.042297136 0.928777159 0.997637226 1.077495232 1 13.09574115 VAPAQPSEEGPGR ddPTM_HeLa_Curcumin_4h_R1 1 VAPAQPSEEGPGR 13 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 0 138.76 0.0006725 2159500 477.61 380.41 478.96 385.88 563.93 464.45 398.57 330.79 570.86 390.05 FALSE FALSE TRUE 439.8066645 413.2909453 496.7106789 384.2833308 557.2055031 368.1178346 409.7528015 431.6463482 508.2380862 403.6042085 1.089697915 1.024000584 1.230687561 0.952129147 1.380574066 0.912076304 1.015234214 1.069479305 1.259248728 1 8.656797408 -9.154843574 0.782850028 0.996815558 1.085180264 0 0.151771145 1.767365361 1.848959668 0.096253515 0.024054639 7.00E-10 9.154843574 0.088364706 VAPAQPSEEGPGRK ddPTM_HeLa_Curcumin_4h_R1 2 VAPAQPSEEGPGRK 14 1 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 0 ; ; 107.39 0.00065343 3121800 918.74 666.5 741.43 700.26 822.95 989.87 880.24 818.72 750.16 678.91 FALSE FALSE TRUE 846.0207595 724.1092901 768.908048 697.3625097 813.1368587 784.5598039 904.9371654 1068.343959 667.8693248 702.502072 1.204296462 1.030757515 1.094527801 0.992683919 1.157486776 1.116807815 1.288162984 1.520769834 0.950700861 1 9.45635867 -4.315371461 1.425255204 1.088199372 1.6735878 0.782234924 0.075658489 0.42690894 0.826222477 0.011999825 0.344585155 4.84E-05 4.315371461 0.585388428 VAPEEHPVLLT(ph)EAPLNPK ddPTM_HeLa_Curcumin_4h_R1 2 VAPEEHPVLLTEAPLNPK 18 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P60709;P63261 ACTB;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 1 0 VAPEEHPVLLT(1)EAPLNPK;VAPEEHPVLLT(1)EAPLNPK ; 134.06 0.00025082 26055700 9695.9 7723.7 9161.1 9345.6 9671.9 12478.2 9043.6 8715.3 9988.6 8608.2 TRUE FALSE FALSE 8928.459284 8391.302212 9500.618425 9306.930383 9556.568909 9890.080662 9297.339076 11372.55485 8892.87557 8907.334309 1.002371638 0.942066607 1.066606248 1.044861466 1.072887643 1.110330018 1.043784678 1.276762997 0.99837676 1 13.12077803 -1 0.464071374 1.000019368 6.923433103 0.742497709 0.043849953 28.66799332 0.300114735 0.008576117 163.5839581 0.1 1 5.923413735 VAPEEHPVLLTEAPLNPK ddPTM_HeLa_Curcumin_4h_R1 4 VAPEEHPVLLTEAPLNPK 18 0 P60709;A0A2R8Y793;A0A2R8YGF8;E7EVS6;G5E9R0;P63261;I3L3I0;I3L1U9;I3L4N8;K7EM38;I3L3R2;J3KT65 P60709;P63261 ACTB;ACTG1 "Actin, cytoplasmic 1;Actin, cytoplasmic 1, N-terminally processed;Actin, cytoplasmic 2;Actin, cytoplasmic 2, N-terminally processed" 0 0 ;;; ;;; 231.13 2.27E-37 1243531300 16988.8 15336.2 14473 14182.6 13996.1 22738.8 17641.9 17681.9 18241.8 15825 FALSE FALSE TRUE 15644.11855 16661.79279 15009.38211 14123.91616 13829.20565 18022.51656 18136.88423 23073.02991 16240.72018 16374.91757 0.955370828 1.017519186 0.916608102 0.862533573 0.844535894 1.100617239 1.107601559 1.409047087 0.991804698 1 13.99920002 -4.220426075 1.383501539 0.962258051 1.618365926 0.817280853 0.06583094 0.456203254 0.708187032 0.010128764 0.426790407 6.02E-05 4.220426075 0.656107875 REGPVGGES(ph)DSEEMFEK ddPTM_HeLa_Curcumin_4h_R1 4 REGPVGGESDSEEMFEK 17 1 Q9Y4B5;Q9Y4B5-2;Q9Y4B5-3;J3QL92 Q9Y4B5 MTCL1 Microtubule cross-linking factor 1 1 0 REGPVGGES(0.824)DS(0.176)EEMFEK;REGPVGGES(0.923)DS(0.077)EEMFEK;REGPVGGES(0.702)DS(0.298)EEMFEK;REGPVGGES(0.827)DS(0.173)EEMFEK ;;; 159.4 0.00023878 99617000 13574.7 11739.8 12231.4 13255.3 13128.8 14103.2 10855.8 4559.36 14880.3 12343.8 TRUE FALSE FALSE 12500.24817 12754.536 12684.70644 13200.45308 12972.24763 11178.03734 11160.38453 5949.487875 13247.96832 12772.74613 0.978665672 0.998574298 0.993107223 1.033485904 1.015619312 0.875147539 0.87376547 0.465795516 1.037205953 1 13.64078112 -4.023276993 1.324756733 0.993384219 2.67E-17 0.949311322 0.036792644 0.303567625 0.305662298 0.004735914 0.470111417 9.48E-05 4.023276993 -0.993384219 down VAPGPSSGSTPGQVPGSSALS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 3 VAPGPSSGSTPGQVPGSSALSSPR 24 0 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-5 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 VAPGPSSGSTPGQVPGS(0.053)S(0.145)ALS(0.401)S(0.401)PR;VAPGPSSGSTPGQVPGS(0.043)S(0.04)ALS(0.459)S(0.459)PR;VAPGPSSGSTPGQVPGS(0.005)S(0.017)ALS(0.489)S(0.489)PR ;; 152.09 1.75E-07 11156000 4039.27 3267.95 3882.98 4152.66 3925.75 4983.24 2897.75 1727.16 4585.61 3572.46 TRUE FALSE FALSE 3719.557517 3550.417036 4026.886655 4135.477393 3878.937995 3949.659851 2979.053066 2253.763133 4082.580056 3696.602719 1.006209701 0.960454046 1.089347966 1.118723787 1.049325094 1.068456675 0.805889432 0.609684974 1.10441407 1 11.85198429 -4.523986181 2.970730034 1.021142773 0.619192089 0.865242554 0.055455596 0.071144457 1.165887569 0.007649215 0.050263609 2.99E-05 4.523986181 -0.401950684 VAPGPSSGSTPGQVPGSSALS(ph)SPRR ddPTM_HeLa_Curcumin_4h_R1 1 VAPGPSSGSTPGQVPGSSALSSPRR 25 1 Q8NEY1-2;Q8NEY1-3;Q8NEY1;A0A0A0MRJ3;Q8NEY1-7;Q8NEY1-4;Q8NEY1-5 Q8NEY1-2 NAV1 Neuron navigator 1 1 0 VAPGPSSGSTPGQVPGS(0.161)S(0.161)ALS(0.401)S(0.276)PRR 83.026 5.55E-05 34411000 1343.2 678.5 1078.4 887 1047.7 888.29 811.23 373.83 1224.8 862.03 TRUE FALSE FALSE 1236.884303 737.1465167 1118.366453 883.329829 1035.206862 704.0486409 833.9909305 487.8090461 1090.442504 891.9854783 1.38666417 0.826410894 1.253794462 0.990296199 1.160564703 0.789305048 0.934982632 0.546880031 1.222489077 1 9.800876413 -3.939801585 0.592625123 1.162716324 9.42E-15 0.52661133 0.164571724 3.078254324 0.565777042 0.03401417 2.660121368 0.000114868 3.939801585 -1.162716324 VAPPYPHLFSSCSPPGMVLDGS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 VAPPYPHLFSSCSPPGMVLDGSPK 24 0 Q9BUK6-2;Q9BUK6;V9GYF2;Q9BUK6-6;Q9BUK6-5 Q9BUK6-2 MSTO1 Protein misato homolog 1 1 0 VAPPYPHLFSSCSPPGMVLDGS(0.999)PK 102.28 3.36E-06 13158000 1855.3 2204.7 1933.1 1445.7 2666.4 6983.4 2881.2 2245.3 3010.8 2000.3 TRUE FALSE FALSE 1708.451047 2395.264444 2004.742387 1439.718076 2634.604921 5534.964121 2962.038718 2929.881634 2680.522773 2069.810276 0.825414323 1.157238647 0.968563356 0.695579732 1.272872665 2.674140806 1.431067742 1.415531495 1.295057235 1 11.01528282 -5.51438691 24.42453555 0.928317101 1.828358494 0.521898877 0.360836675 143.9399819 414004.6534 0.046593741 0.097067027 3.06E-06 5.51438691 0.900041394 ESSVK(ac)TVR ddPTM_HeLa_Curcumin_4h_R1 1 ESSVKTVR 8 1 O95696-2;O95696;J3KQ61 O95696-2 BRD1 Bromodomain-containing protein 1 0 1 ESSVK(1)TVR 112.11 0.0052374 27626000 3832.3 3372.2 2926 2900.4 3418.2 3831 2191.1 1210.8 3750.1 3424.6 FALSE TRUE FALSE 3528.969411 3663.677942 3034.440134 2888.398913 3377.440197 3036.407416 2252.576369 1579.967346 3338.723412 3543.604595 0.995869973 1.033884522 0.856314539 0.815101921 0.953108652 0.856869703 0.635673735 0.445864459 0.942182832 1 11.79100192 -4.075351574 0.635803072 0.991295878 2.34E-19 0.862871139 0.064900865 0.949053027 0.223994424 0.01165241 0.720111865 8.41E-05 4.075351574 -0.991295878 down VAPVINNGS(ph)PTILGK ddPTM_HeLa_Curcumin_4h_R1 2 VAPVINNGSPTILGK 15 0 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 0 VAPVINNGS(0.994)PT(0.006)ILGK;VAPVINNGS(0.999)PT(0.001)ILGK ; 231.41 5.73E-21 395150000 7167.8 6746.2 6418.7 7147.4 7607.6 8377.6 7240.6 1375.42 7426.1 6449.1 TRUE FALSE FALSE 6600.461067 7329.311468 6656.582668 7117.825953 7516.884339 6639.991325 7443.751749 1794.779226 6611.475409 6673.205745 0.989098991 1.098319421 0.997508982 1.066627679 1.126427781 0.995022719 1.115468642 0.268953078 0.990749523 1 12.70416427 -4.257073473 24.9937169 1.021430238 0.268952777 0.944250679 0.056158657 73.94372651 423293.5085 0.00797646 0.083886689 5.53E-05 4.257073473 -0.752477461 VAPVINNGS(ph)PTILGKR ddPTM_HeLa_Curcumin_4h_R1 1 VAPVINNGSPTILGKR 16 1 H0Y4T7;E7ESY4;Q13330-3;Q13330;F8W9Y9 H0Y4T7 MTA1 Metastasis-associated protein MTA1 1 0 VAPVINNGS(0.751)PT(0.249)ILGKR 79.804 0.020093 29682000 2180.2 1892.8 1910.6 1687.2 1498.6 3805.9 2552.9 1702.1 2684.3 2279.1 TRUE FALSE FALSE 2007.634869 2056.405198 1981.408517 1680.218813 1480.730174 3016.513439 2624.527503 2221.062454 2389.839006 2358.298555 0.851306492 0.871986795 0.840185613 0.712470781 0.627880711 1.279105833 1.112890265 0.941807156 1.01337424 1 11.20353066 -5.247474124 24.99896806 0.882802528 1.111429981 0.429013228 0.135866379 712.0811073 1274681.983 0.020484968 0.051940951 5.66E-06 5.247474124 0.228627453 VAQGAT(ph)EKSPEDKVQIAANEETQER ddPTM_HeLa_Curcumin_4h_R1 1 VAQGATEKSPEDKVQIAANEETQER 25 2 P49321-4;P49321;P49321-3 P49321-4 NASP Nuclear autoantigenic sperm protein 1 0 VAQGAT(0.574)EKS(0.426)PEDKVQIAANEETQER 62.735 0.0013961 14684000 3214.6 2451 2786.7 2471.8 3311.1 2863.8 2614.8 2927.2 2632.6 2093.5 TRUE FALSE FALSE 2960.161018 2662.853519 2889.977553 2461.572347 3271.617295 2269.815598 2688.164251 3819.689805 2343.810366 2166.248969 1.366491599 1.229246295 1.334092985 1.136329379 1.510268368 1.0478092 1.240930423 1.763273686 1.081967216 1 11.08098335 -12.04375838 0.292527543 5.62E-11 1.34651607 0.271014706 0.189470835 18.80779802 0.549165578 11.03211473 0.082147583 9.04E-13 12.04375838 1.34651607 VAQGATEKS(ph)PEDKVQIAANEETQER ddPTM_HeLa_Curcumin_4h_R1 1 VAQGATEKSPEDKVQIAANEETQER 25 2 P49321-4;P49321;P49321-3 P49321-4 NASP Nuclear autoantigenic sperm protein 1 0 VAQGAT(0.11)EKS(0.889)PEDKVQIAANEETQER 48.685 0.0078823 8792600 1128.3 1150.2 1105.6 1003.4 1254.9 991.48 1031 912.59 991 1030.2 TRUE FALSE FALSE 1038.993864 1249.618163 1146.574509 999.2481967 1239.936137 785.8358717 1059.927085 1190.83449 882.2897794 1065.999373 0.974666487 1.172250373 1.075586475 0.937381599 1.163167792 0.737182302 0.994303666 1.117106182 0.827664445 1 10.05799087 -4.260289365 22.23050189 0.997819695 1.117106341 0.079204692 0.128415084 40.69655747 786140.1153 0.014990584 0.122865498 5.49E-05 4.260289365 0.119286646 VAQILK(ac)EPK ddPTM_HeLa_Curcumin_4h_R1 2 VAQILKEPK 9 1 A0A494C0K9;H7C0C1;P48047 A0A494C0K9 ATP5O "ATP synthase subunit O, mitochondrial" 0 1 ; VAQILK(1)EPK;VAQILK(1)EPK 139.96 4.60E-05 3076800 1561.89 1275.54 1376.88 1259.72 2492 4394.7 2891.8 2368.6 3226.1 1365.35 FALSE TRUE FALSE 1438.264758 1385.791994 1427.908384 1254.507612 2462.284528 3483.189682 2972.936125 3090.775236 2872.204901 1412.795811 1.018027338 0.980886256 1.010696927 0.887961022 1.742845292 2.46545867 2.104292851 2.187701303 2.032993642 1 10.46433725 -5.586228889 3.53472633 0.999479779 2.229972628 0.661636269 0.342184842 0.024941353 0.631424488 0.013878449 0.029791714 2.59E-06 5.586228889 1.230492849 VAQPTITDNKDGTVTVR ddPTM_HeLa_Curcumin_4h_R1 2 VAQPTITDNKDGTVTVR 17 1 P21333-2;P21333;H0Y5F3;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 102.72 0.0022746 35517000 8185 6228.3 7644.4 7204 7873.8 9046.4 6769.4 6675.6 6742.3 7184.1 FALSE FALSE TRUE 7537.148613 6766.646499 7927.708189 7174.191757 7779.910078 7170.074666 6959.331145 8710.959709 6002.686558 7433.74694 1.013909765 0.910260539 1.066448489 0.965084205 1.046566441 0.964530367 0.936180798 1.171812786 0.807491378 1 12.85987386 -4.248483189 24.83856127 0.997841306 1.171812907 0.338923619 0.075651896 1020.363979 1956122.905 0.005715869 0.141650934 5.64E-05 4.248483189 0.173971601 VAQRS(ph)PVDSGTILR ddPTM_HeLa_Curcumin_4h_R1 1 VAQRSPVDSGTILR 14 1 P49454 P49454 CENPF Centromere protein F 1 0 VAQRS(0.994)PVDS(0.004)GT(0.002)ILR 62.709 0.019706 15130000 1106.3 925.92 898.64 964.89 1095.6 1713.2 1335 895.65 1130.4 850.83 TRUE FALSE FALSE 1018.735188 1005.952399 931.9443889 960.8975408 1082.535686 1357.863008 1372.456507 1168.729562 1006.397948 880.3962792 1.157132546 1.142613188 1.058551031 1.091437531 1.229600478 1.542331607 1.558907664 1.327503977 1.143119266 1 9.782009238 -5.46539695 3.11300898 1.08195244 1.483500228 0.834231744 0.074740937 0.07618888 1.453272223 0.012255202 0.02884629 3.42E-06 5.46539695 0.401547788 VAS(ph)DTEEADR ddPTM_HeLa_Curcumin_4h_R1 1 VASDTEEADR 10 0 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 0 VAS(0.982)DT(0.018)EEADR 98.898 0.013308 37300000 1479.3 1273.5 1262.2 1297.7 1299.3 1247 1585.4 829.2 1345 1312.7 TRUE FALSE FALSE 1362.211844 1383.575665 1308.978242 1292.330461 1283.806696 988.3581434 1629.882057 1082.019263 1197.456865 1358.316227 1.002867975 1.01859614 0.9636771 0.95142091 0.945145667 0.72763479 1.199928282 0.79658863 0.881574438 1 10.40760367 -6.350857334 1.909219402 1.002534649 0.926686829 0.022536164 0.121217615 0.636764063 4.540759804 0.016786088 0.028484657 4.46E-07 6.350857334 -0.07584782 VAS(ph)DTEEADRTSSK ddPTM_HeLa_Curcumin_4h_R1 3 VASDTEEADRTSSK 14 1 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 0 VAS(0.994)DT(0.005)EEADRTS(0.001)SK;VAS(0.999)DT(0.001)EEADRTSSK;VAS(0.543)DT(0.44)EEADRT(0.013)S(0.004)S(0.001)K ;; 182.72 0.00088071 102121000 7602.7 6405.6 7054.5 7495 6242.6 8483.8 5929.9 4579.9 8680.8 7809.4 TRUE FALSE FALSE 7000.938273 6959.271521 7315.945976 7463.987676 6168.161072 6724.164248 6096.277034 5976.290427 7728.537958 8080.776069 0.866369543 0.861213262 0.905351901 0.923672134 0.763312957 0.832118622 0.754417272 0.73956887 0.956410361 1 12.98027814 -1.000000006 0.059635348 1.246996004 0.021928407 0.759308789 0.041287803 109.7326969 0.494158494 2.108071836 11.76993908 0.099999999 1.000000006 -1.225067598 NRPTS(ph)ISWDGLDSGK ddPTM_HeLa_Curcumin_4h_R1 1 NRPTSISWDGLDSGK 15 1 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 1 0 NRPT(0.216)S(0.705)IS(0.074)WDGLDS(0.004)GK 76.118 0.0089592 43735000 6616.2 5077.6 6381.2 5628.7 6663.9 10141 7359.5 8411.9 6017.6 5074.6 TRUE FALSE FALSE 6092.520789 5516.485119 6617.692885 5605.409931 6584.437345 8037.642287 7565.987763 10976.64959 5357.484335 5250.941972 1.16027197 1.050570573 1.260286806 1.067505594 1.253953553 1.530704839 1.440881998 2.090415328 1.020290143 1 12.35836054 -1 0.465832135 1.068941777 25.68323992 0.901828041 0.099279284 16.57332544 0.172816067 0.020137168 394.8503237 0.1 1 24.61429814 up VAS(ph)LTLHNK ddPTM_HeLa_Curcumin_4h_R1 2 VASLTLHNK 9 0 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3 RAI14 Ankycorbin 1 0 VAS(0.984)LT(0.016)LHNK;VAS(0.989)LT(0.011)LHNK ; 93.442 0.0080205 57188000 8354.7 7035.5 7178.9 8169.9 8210.7 11924.6 10973.9 5077.2 8855.2 9132.5 TRUE FALSE FALSE 7693.416679 7643.61727 7444.956349 8136.095119 8112.792765 9451.303542 11281.7981 6625.214907 7883.806715 9449.853695 0.814130771 0.808860911 0.787838266 0.860975776 0.85850988 1.000153425 1.193859552 0.701091797 0.834278177 1 13.20607628 -3.982582347 18.64655851 0.909616826 0.260626408 0.210734489 0.11912727 25736522.36 578004053.2 0.017580997 476515200.9 0.000104092 3.982582347 -0.648990418 VAS(ph)SPAPPEGPSHPR ddPTM_HeLa_Curcumin_4h_R1 2 VASSPAPPEGPSHPR 15 0 H7BYJ3;O14578;O14578-4;O14578-3 H7BYJ3 CIT Citron Rho-interacting kinase 1 0 VAS(0.5)S(0.5)PAPPEGPSHPR;VAS(0.553)S(0.447)PAPPEGPSHPR ; 82.01 0.0067045 35010000 2208.1 2341.96 2202.72 2168.75 2227.97 2860.9 2185.99 480.18 2345.97 2172.57 TRUE FALSE FALSE 2033.326555 2544.388587 2284.354741 2159.776287 2201.402913 2267.517091 2247.322996 626.5846715 2088.62296 2248.066646 0.904477881 1.131811902 1.016141913 0.960726094 0.979242727 1.008652077 0.999669205 0.278721573 0.929075196 1 11.13446909 -4.260348134 24.94956213 0.977765144 0.278721344 0.928443189 0.059300602 18.02959426 412160.8722 0.008951372 0.073461338 5.49E-05 4.260348134 -0.699043801 VASALPGMENVQEK(ac)SK ddPTM_HeLa_Curcumin_4h_R1 1 VASALPGMENVQEKSK 16 1 Q9NRW1-2;Q9NRW1 Q9NRW1-2 RAB6B Ras-related protein Rab-6B 0 1 VASALPGMENVQEK(1)SK 83.397 0.019693 1451700 217.13 155.87 168.65 317.2 450.28 356.85 314.99 173.88 438.76 268.81 FALSE TRUE FALSE 199.9439314 169.3427083 174.9003174 315.8875104 444.9107051 282.8352875 323.8277716 226.8952116 390.6291257 278.1511275 0.718832 0.608815466 0.628796004 1.135668632 1.599528677 1.016840342 1.164215204 0.815726377 1.404377287 1 8.119725143 -6.162773793 7.671577162 0.824330517 1.167565994 0.180040718 0.282251048 0.256276886 17.77843316 0.03519669 0.058522725 6.87E-07 6.162773793 0.343235477 VASDT(ph)EEADR ddPTM_HeLa_Curcumin_4h_R1 2 VASDTEEADR 10 0 D6RA28;A0A590UJ84;B1AKN3;Q9P2R6-2;Q9P2R6 D6RA28 RERE Arginine-glutamic acid dipeptide repeats protein 1 0 VAS(0.138)DT(0.862)EEADR;VAS(0.019)DT(0.981)EEADR ; 135.8 0.0060878 16744100 3983.3 3016.7 3680 4356.3 4704.6 4021.5 4035 2599.3 3711.9 3811.7 TRUE FALSE FALSE 3668.017602 3277.450106 3816.384037 4338.274785 4648.500718 3187.395568 4148.21124 3391.814604 3304.713857 3944.156291 0.929987894 0.830963548 0.967604668 1.099924664 1.178579238 0.808131152 1.05173602 0.859959483 0.83787599 1 11.94550101 -4.423190455 0.001849188 1.382181176 0.551828769 0 0.120486822 5336217.486 1629.654807 361281.7514 370538.0631 3.77E-05 4.423190455 -0.830352407 VASEAPLEHKPQVEAS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 VASEAPLEHKPQVEASSPR 19 1 Q8TD19 Q8TD19 NEK9 Serine/threonine-protein kinase Nek9 1 0 VASEAPLEHKPQVEAS(0.5)S(0.5)PR;VASEAPLEHKPQVEAS(0.5)S(0.5)PR ; 67.214 0.0052871 58082000 4464.6 3960.6 4036.2 4523.1 4235.4 4261.5 3085.5 4078.7 5021.7 4411.5 TRUE FALSE FALSE 4111.222199 4302.936616 4185.785123 4504.384611 4184.895621 3377.616863 3172.070826 5322.276854 4470.832074 4564.799297 0.900635917 0.94263435 0.916970244 0.986765095 0.916775383 0.739926696 0.694898202 1.165938853 0.979414818 1 12.15633571 -5.508867943 23.11471461 0.950274022 0.846157611 0.088068386 0.120295205 359.1149394 592457.1237 0.016259644 0.035008968 3.10E-06 5.508867943 -0.104116411 VASET(ph)HSEGS(ph)EYEELPK ddPTM_HeLa_Curcumin_4h_R1 1 VASETHSEGSEYEELPK 17 0 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 2 0 VAS(0.344)ET(0.562)HS(0.292)EGS(0.713)EY(0.089)EELPK 102.38 0.0078019 8234900 2527.9 1988 1924.8 1648.4 2266.4 2899.6 1851.1 1065 2627.3 1991.2 TRUE FALSE FALSE 2327.814048 2159.833862 1996.134781 1641.579358 2239.37466 2298.190275 1903.036884 1389.713597 2339.091763 2060.394052 1.129790705 1.04826252 0.968812145 0.796730779 1.086867174 1.115412983 0.923627634 0.67448923 1.135264277 1 11.00870456 -6.716458053 4.16479078 1.062420004 0.93529149 0.25643191 0.125245178 0.2883348 10.58374041 0.0207387 0.029160879 1.92E-07 6.716458053 -0.127128514 VASETHS(ph)EGSEYEELPK ddPTM_HeLa_Curcumin_4h_R1 1 VASETHSEGSEYEELPK 17 0 Q5JSZ5;A0A494C0D3 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 VASET(0.001)HS(0.999)EGS(0.001)EYEELPK 114.3 0.00042563 19575000 3686.9 3081.6 3022.3 3146.2 5288.5 5975.5 3012.5 1489.8 4107.1 3429.3 TRUE FALSE FALSE 3395.077975 3347.959773 3134.309097 3133.181858 5225.438092 4736.113942 3097.022642 1944.033162 3656.561405 3548.46792 0.956772909 0.943494446 0.883285172 0.882967503 1.47258992 1.334692619 0.872777411 0.547851412 1.030462016 1 11.79298055 SAS(ph)SDTSEELNSQDSPPK ddPTM_HeLa_Curcumin_4h_R1 1 SASSDTSEELNSQDSPPK 18 0 J3QRP6;O14745-2;O14745 J3QRP6 SLC9A3R1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 1 0 SAS(0.959)S(0.041)DTSEELNSQDSPPK 376.94 3.86E-222 61700000 3609.3 3182 3201.4 3676.6 4481.3 4628.5 4675 4789 3029.7 2990.6 TRUE FALSE FALSE 3323.620096 3457.037901 3320.0467 3661.387203 4427.863424 3668.496926 4806.167918 6249.144054 2697.34949 3094.523127 1.074033045 1.117147218 1.072878296 1.183183015 1.430871007 1.185480533 1.553120697 2.019420698 0.871652716 1 11.59550139 -1 0.44764656 1.034105224 22.59820595 0.890940701 0.104996934 14.27516431 0.15479992 0.019246075 283.3682341 0.1 1 21.56410073 up SAGAAQK(ac)KPAATTAK ddPTM_HeLa_Curcumin_4h_R1 2 SAGAAQKKPAATTAK 15 2 Q6PL18;E5RHW7;E5RIP2 Q6PL18 ATAD2 ATPase family AAA domain-containing protein 2 0 1 ; SAGAAQK(0.986)K(0.014)PAATTAK;SAGAAQK(0.974)K(0.026)PAATTAK 108.14 0.00063456 17737000 10637.3 10212.3 9723.3 9687.9 10206.5 12470.9 9376.6 3560.8 11631.3 11171.8 FALSE TRUE FALSE 9795.346481 11095.00571 10083.65405 9647.814037 10084.79415 9884.294764 9639.68216 4646.471528 10355.37549 11560.01922 0.847346903 0.959773985 0.872286963 0.834584602 0.872385587 0.855041378 0.833881153 0.401943236 0.895792238 1 13.49685618 -4.056925699 1.709237247 0.912147016 5.99E-16 0.886827624 0.051824537 0.507705321 0.938241721 0.009840621 0.888452883 8.77E-05 4.056925699 -0.912147016 down HGAPAAPS(ph)PPPR ddPTM_HeLa_Curcumin_4h_R1 3 HGAPAAPSPPPR 12 0 Q4KMP7 Q4KMP7 TBC1D10B TBC1 domain family member 10B 1 0 HGAPAAPS(1)PPPR;HGAPAAPS(1)PPPR;HGAPAAPS(1)PPPR ;; 87.447 0.0083021 40539100 16834.6 13386.8 14432.6 16027.4 15563.9 18248.5 12716.8 5700 18028 14849.6 TRUE FALSE FALSE 15502.12365 14543.89534 14967.48485 15961.08287 15378.31066 14463.5554 13073.59918 7437.90376 16050.3735 15365.62249 1.008883542 0.946521714 0.974089065 1.038752766 1.00082575 0.941293163 0.850834334 0.484061336 1.044563831 1 13.90741859 -4.02282004 1.35754397 0.999884588 5.78E-10 0.967382899 0.028472956 0.233883085 0.247523573 0.003715127 0.373121995 9.49E-05 4.02282004 -0.999884587 down VASPSQGQVGSS(ph)SPKR ddPTM_HeLa_Curcumin_4h_R1 1 VASPSQGQVGSSSPKR 16 1 A0A0D9SF60;Q99569-2;Q99569 A0A0D9SF60 PKP4 Plakophilin-4 1 0 VASPSQGQVGS(0.169)S(0.615)S(0.216)PKR 118.19 0.00049267 20559000 1596.5 1166.4 1545.2 1609.7 1324.4 1923.6 1282.1 769.98 1934.9 1547.2 TRUE FALSE FALSE 1470.13534 1267.218419 1602.466471 1603.039488 1308.607395 1524.623677 1318.072275 1004.743357 1722.646311 1600.965085 0.918280701 0.791534076 1.000937801 1.00129572 0.817386592 0.952315382 0.823298577 0.627586052 1.076004922 1 10.64472613 -3.687670578 0.947777381 0.948328835 9.20E-17 0.59076979 0.081716146 2.50060972 0.800027514 0.011318559 3.161974958 0.000205272 3.687670578 -0.948328835 GHYEVTGSDDET(ph)GKLQGSGVSLASKK ddPTM_HeLa_Curcumin_4h_R1 1 GHYEVTGSDDETGKLQGSGVSLASKK 26 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GHY(0.006)EVT(0.06)GS(0.113)DDET(0.81)GKLQGS(0.009)GVS(0.002)LAS(0.001)KK 46.558 0.013961 181460000 2902.9 2279.9 2162.1 2335.9 1914 3092.2 2067.2 888.82 4030.9 3009.7 TRUE FALSE FALSE 2673.132402 2476.964397 2242.229328 2326.234665 1891.1768 2450.842864 2125.200068 1159.817126 3588.720355 3114.286851 0.858344953 0.79535525 0.719981632 0.746955812 0.607258384 0.786967605 0.682403443 0.372418207 1.152340978 1 11.60468612 -4.01788649 0.154248921 1.090230735 2.74E-16 0.765302443 0.097257938 8.539507999 0.208413794 0.225281786 1.912104764 9.60E-05 4.01788649 -1.090230735 down VATLNS(ph)EEESDPPTYK ddPTM_HeLa_Curcumin_4h_R1 1 VATLNSEEESDPPTYK 16 0 Q00341;Q00341-2;A0A024R4E5;C9JHZ8;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JK79;C9JHS7;C9JT62;C9JQ82;C9JHN6;C9JEJ8;C9JBS3;C9JMQ6 Q00341 HDLBP Vigilin 1 0 VAT(0.011)LNS(0.966)EEES(0.023)DPPTYK 135.26 0.00020283 13053000 6363.8 5135.6 5566.8 6020.2 6423.4 7179.7 5226 4575.3 5726.1 5030.5 TRUE FALSE FALSE 5860.098515 5579.49838 5773.110505 5995.290008 6346.80515 5690.549288 5372.627495 5970.287908 5097.961156 5205.309501 1.125792523 1.071886 1.109081123 1.151764368 1.219294482 1.093220161 1.032143717 1.146961176 0.979377145 1 12.34576823 -9.33128283 0.602074616 0.97939573 1.120923555 0.536236407 0.047843849 0.904282535 0.455613449 0.071730877 0.01130431 4.66E-10 9.33128283 0.141527825 VATLNSEEES(ph)DPPTYK ddPTM_HeLa_Curcumin_4h_R1 3 VATLNSEEESDPPTYK 16 0 Q00341;Q00341-2;A0A024R4E5;C9JHZ8;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JK79;C9JHS7;C9JT62;C9JQ82;C9JHN6;C9JEJ8;C9JBS3;C9JMQ6 Q00341 HDLBP Vigilin 1 0 VAT(0.001)LNS(0.079)EEES(0.919)DPPTYK;VATLNS(0.002)EEES(0.831)DPPT(0.167)YK;VATLNSEEES(1)DPPTYK ;; 233.14 4.27E-22 46059000 13285.5 10313.1 12318.7 13075.6 15000.2 14613.8 10656.9 9483.3 12098.4 10313.8 TRUE FALSE FALSE 12233.93866 11204.51841 12775.24186 13021.49663 14821.33241 11582.73315 10955.90393 12374.71451 10771.23579 10672.20378 1.14633668 1.049878604 1.197057526 1.220131933 1.388778992 1.085317839 1.02658309 1.15952757 1.009279434 1 13.3815705 -8.930438865 0.529672551 0.983066156 1.168093557 0.301678746 0.095747743 1.255404603 0.587894571 0.114085218 0.02734006 1.17E-09 8.930438865 0.185027402 VATLNSEEES(ph)DPPTYKDAFPPLPEK ddPTM_HeLa_Curcumin_4h_R1 1 VATLNSEEESDPPTYKDAFPPLPEK 25 1 Q00341;Q00341-2;A0A024R4E5;C9JHZ8;C9JIZ1;C9J5E5;C9JZI8;C9JES8;C9JK79;C9JHS7;C9JT62;C9JQ82;C9JHN6;C9JEJ8;C9JBS3 Q00341 HDLBP Vigilin 1 0 VATLNS(0.026)EEES(0.45)DPPT(0.285)Y(0.24)KDAFPPLPEK 83.871 4.70E-05 56815000 3489.8 2573.5 2945.6 3274.4 2356.8 3765.9 2317.9 2442.6 3870.9 3362.5 TRUE FALSE FALSE 3213.578648 2795.941873 3054.766527 3260.8514 2328.696699 2984.80989 2382.934036 3187.337496 3446.271955 3479.346625 0.92361555 0.803582446 0.877971314 0.937202226 0.669291379 0.857865057 0.684879747 0.916073573 0.990494 1 11.7646007 -7.345023622 0.472436889 0.998149957 0.78525724 0.417790227 0.083569925 0.533385287 0.296466156 0.034795899 0.038032994 4.52E-08 7.345023622 -0.212892716 VATTPGS(ph)PSLGR ddPTM_HeLa_Curcumin_4h_R1 3 VATTPGSPSLGR 12 0 A0A087WWW7;E9PGF5;E9PF55;A0A494C067;A0A2R8Y4T1;Q9HBL0;H0Y4U1 A0A087WWW7 TNS1 Tensin-1 1 0 VAT(0.251)T(0.091)PGS(0.644)PS(0.014)LGR;VAT(0.002)T(0.274)PGS(0.709)PS(0.015)LGR;VAT(0.022)T(0.38)PGS(0.528)PS(0.069)LGR ;; 139.19 0.0012874 85421000 9224.3 7146.1 8033.3 8338.8 9037.4 9676.4 7124.1 3732.08 8940 7684.9 TRUE FALSE FALSE 8494.186922 7763.777042 8331.021165 8304.296255 8929.634908 7669.405564 7323.983072 4869.974012 7959.304367 7951.949703 1.068189216 0.976336286 1.047670254 1.044309454 1.122949118 0.964468571 0.921029854 0.612425153 1.000924888 1 12.95709292 -4.131150422 1.543577999 1.035229837 0.347770693 0.898130737 0.042394829 0.329629416 0.566331107 0.006234038 0.375136011 7.39E-05 4.131150422 -0.687459145 VAVATPAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VAVATPAKK 9 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 ; VAVATPAK(1)K;VAVATPAK(1)K 138.1 5.21E-05 188806000 22022 17325 19024.6 17455 18822.5 24180 20785 16320.9 22153 17095.3 FALSE TRUE FALSE 20278.93546 18822.4958 19729.66841 17382.77583 18598.05398 19164.79544 21368.17116 21297.06728 19722.87132 17689.3604 1.146391673 1.064057454 1.115340971 0.98266842 1.051369499 1.083408049 1.207967426 1.203947842 1.114956724 1 14.11059426 -13.52277179 0.015735647 1.59E-06 1.955402059 0.156883628 0.066646621 4898.002016 6.223938437 482.4938601 309.1202491 3.00E-14 13.52277179 1.955400469 VAVEEVDEEGKFVR ddPTM_HeLa_Curcumin_4h_R1 3 VAVEEVDEEGKFVR 14 1 P02545;P02545-3;P02545-6;P02545-5;P02545-4;A0A0C4DGC5;P02545-2;Q5TCI8 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 0 ;; ;; 173.19 0.00016824 138599300 7945.7 6800.9 7119 7487.6 7397.2 9218.5 6898.7 6274.71 9064.5 7927.08 FALSE FALSE TRUE 7316.789461 7388.739492 7382.836403 7456.618295 7308.993221 7306.479186 7092.258955 8187.840194 8070.147028 8202.54544 0.892014499 0.90078617 0.900066505 0.909061504 0.891064033 0.890757539 0.864641227 0.998207234 0.983858863 1 13.00185597 -9.24191576 0.823259141 1.004404563 0.902496231 0.50744745 0.033605364 0.39105321 0.444349224 0.025805936 0.006033783 5.73E-10 9.24191576 -0.101908333 VAVEYLDPS(ph)PEVQK ddPTM_HeLa_Curcumin_4h_R1 1 VAVEYLDPSPEVQK 14 0 O43684-2;O43684;J3QT28 O43684-2 BUB3 Mitotic checkpoint protein BUB3 1 0 VAVEYLDPS(1)PEVQK 144.88 0.00064342 11906000 6212.5 4311.5 4475.1 4573.9 4882 6653.5 5631.1 4229.9 5844.1 5747.9 TRUE FALSE FALSE 5720.77407 4684.166848 4640.951143 4554.974414 4823.785339 5273.4891 5789.093511 5519.577038 5203.016851 5947.639097 0.961856289 0.787567432 0.780301405 0.765845799 0.811042039 0.886652504 0.973343106 0.928028239 0.874803727 1 12.53810139 -7.391700487 5.407460551 0.983414811 0.847020977 0.237124072 0.072219288 0.160095905 6.370651487 0.012535629 0.014245312 4.06E-08 7.391700487 -0.136393834 VAVLLLAGGQGTR ddPTM_HeLa_Curcumin_4h_R1 2 VAVLLLAGGQGTR 13 0 Q16222-2;Q3KQV9;Q16222-3;Q16222 Q16222-2 UAP1;UAP1L1 UDP-N-acetylhexosamine pyrophosphorylase;UDP-N-acetylgalactosamine pyrophosphorylase;UDP-N-acetylglucosamine pyrophosphorylase;UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 0 0 ; ; 134.57 0.0010146 2369700 1656.74 1520.6 1538.46 1760.46 1458.38 1771.08 1681.69 1658.45 1650.85 2040.51 FALSE FALSE TRUE 1525.607281 1652.033888 1595.476681 1753.175683 1440.989771 1403.738044 1728.873695 2164.10377 1469.755885 2111.417571 0.722551191 0.782428787 0.755642419 0.830331104 0.682475031 0.664832037 0.818821307 1.024952999 0.696099107 1 11.04399621 -9.34707861 0.991871672 1.004344654 0.775642432 0 0.133397181 0.43545594 0.743570266 0.07243488 0.017568265 4.50E-10 9.34707861 -0.228702222 VAVNALAVGEPGT(ph)ASKPASPIGGPTQEEK ddPTM_HeLa_Curcumin_4h_R1 1 VAVNALAVGEPGTASKPASPIGGPTQEEK 29 1 Q96L91-4;Q96L91-3;Q96L91-5;Q96L91-2;Q96L91 Q96L91-4 EP400 E1A-binding protein p400 1 0 VAVNALAVGEPGT(0.517)AS(0.269)KPAS(0.213)PIGGPT(0.001)QEEK 94.594 9.01E-08 22784000 1518.8 1196.5 1595.2 1811.3 1475.4 1518.1 1364.6 1492.3 1665.2 1485.5 TRUE FALSE FALSE 1398.585377 1299.920128 1654.319515 1803.805321 1457.806819 1203.228947 1402.887003 1947.2954 1482.531726 1537.121014 0.909873305 0.845684963 1.076245461 1.173495973 0.948400812 0.782780885 0.9126718 1.266845864 0.964486018 1 10.58601503 -6.737263735 24.97840136 0.94786931 1.013575962 0.102566117 0.1327488 616.2617667 636723.3755 0.021675675 0.030644946 1.83E-07 6.737263735 0.065706652 VAVNALAVGEPGTAS(ph)KPASPIGGPTQEEK ddPTM_HeLa_Curcumin_4h_R1 1 VAVNALAVGEPGTASKPASPIGGPTQEEK 29 1 Q96L91-4;Q96L91-3;Q96L91-5;Q96L91-2;Q96L91 Q96L91-4 EP400 E1A-binding protein p400 1 0 VAVNALAVGEPGT(0.216)AS(0.676)KPAS(0.103)PIGGPT(0.005)QEEK 92.38 6.09E-08 31378000 934.99 614.02 878.19 1076.8 774.68 801.14 1094.4 1130.3 974.82 905.11 TRUE FALSE FALSE 860.9845549 667.0931528 910.7364939 1072.344487 765.442447 634.9745333 1125.105919 1474.923267 867.8846849 936.5625051 0.919302823 0.712278304 0.97242468 1.144979092 0.817289228 0.677984149 1.201314288 1.574826302 0.926670329 1 9.871231471 -4.449050335 3.679467456 0.931280104 1.552396617 0.704423022 0.135830722 0.105763068 2.549783947 0.019150526 0.129874317 3.56E-05 4.449050335 0.621116513 VAVPTGPTPLDS(ph)TPPGGAPHPLTGQEEAR ddPTM_HeLa_Curcumin_4h_R1 3 VAVPTGPTPLDSTPPGGAPHPLTGQEEAR 29 0 A0A0A0MR08;E7ESU0;O94966-2;O94966-4;O94966-3;O94966;O94966-7;O94966-6;O94966-5 A0A0A0MR08 USP19 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 19 1 0 VAVPT(0.001)GPT(0.028)PLDS(0.486)T(0.486)PPGGAPHPLTGQEEAR;VAVPT(0.001)GPT(0.006)PLDS(0.496)T(0.496)PPGGAPHPLTGQEEAR;VAVPT(0.028)GPT(0.022)PLDS(0.94)T(0.01)PPGGAPHPLTGQEEAR ;; 146.04 2.33E-12 39749000 6467.2 5841.4 5409.1 6270.3 6285.7 8873.6 6400.7 3429.83 6813.5 5500.2 TRUE FALSE FALSE 5955.314296 6346.304587 5609.566004 6244.35516 6210.747133 7033.115334 6580.286415 4475.569378 6066.076097 5691.331541 1.046383303 1.115082568 0.98563332 1.097169461 1.091264336 1.235759204 1.156194533 0.786383528 1.065844795 1 12.47455051 -8.087638289 0.649670436 1.003794304 1.078982465 0 0.114286531 1.489465762 1.408164039 0.047127189 0.029618241 8.17E-09 8.087638289 0.075188161 VAVPTGPTPLDST(ph)PPGGAPHPLTGQEEAR ddPTM_HeLa_Curcumin_4h_R1 1 VAVPTGPTPLDSTPPGGAPHPLTGQEEAR 29 0 A0A0A0MR08;E7ESU0;O94966-2;O94966-4;O94966-3;O94966;O94966-7;O94966-6;O94966-5 A0A0A0MR08 USP19 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 19 1 0 VAVPT(0.004)GPT(0.024)PLDS(0.452)T(0.52)PPGGAPHPLTGQEEAR 76.899 4.44E-05 6306500 1337.6 772.75 933.4 847.73 951.87 1167.7 1098.7 525.2 1140.6 929.71 TRUE FALSE FALSE 1231.727549 839.5430667 967.9926251 844.2223179 940.5195719 925.5058573 1129.526565 685.3310623 1015.479034 962.0173533 1.280358971 0.872690148 1.006211189 0.877554147 0.977653437 0.962046947 1.174122859 0.712389501 1.05557247 1 9.909919108 -7.247444166 24.93387204 1.13239174 0.951753587 0.262621248 0.129447028 779.4951824 1388749.192 0.0236328 0.028866622 5.66E-08 7.247444166 -0.180638152 VAVTEGCQPSR ddPTM_HeLa_Curcumin_4h_R1 1 VAVTEGCQPSR 11 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 154.85 2.36E-07 6679800 1614.2 2765 1560.4 1595.4 1585 1221.3 1497.4 1512.9 1541.3 2001.9 FALSE FALSE TRUE 1486.434367 3003.994279 1618.229797 1588.798658 1566.09991 967.9886131 1539.413014 1974.176245 1372.223246 2071.465876 0.717576082 1.450178018 0.781200316 0.766992436 0.756034617 0.467296432 0.74315152 0.953033438 0.662440672 1 11.01643634 -6.539344655 24.99633123 0.916625719 0.728709882 0.166619498 0.22736291 370.7714924 562853.5408 0.035621315 0.050383631 2.89E-07 6.539344655 -0.187915837 VAVTSSSSSSSSSSSIPS(ph)AEKVPTTK ddPTM_HeLa_Curcumin_4h_R1 2 VAVTSSSSSSSSSSSIPSAEKVPTTK 26 1 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;J3KSW8;Q6WCQ1-3 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 VAVTSSSSSSSSSSSIPS(0.997)AEKVPT(0.002)T(0.001)K;VAVTSSSSS(0.001)S(0.001)S(0.003)S(0.004)S(0.023)S(0.023)S(0.014)IPS(0.918)AEKVPT(0.006)T(0.008)K ; 110.91 4.62E-08 48382000 6387.4 5426.3 5268.3 5489.7 5387.1 9320.7 7510.4 2389.57 6640.4 5174.9 TRUE FALSE FALSE 5881.83055 5895.325193 5463.547832 5466.985076 5322.862351 7387.481754 7721.121611 3118.138893 5911.964733 5354.72739 1.098436974 1.10095711 1.020322312 1.020964221 0.994049176 1.379618647 1.44192618 0.582315152 1.104064559 1 12.38659741 VAVVAGYGDVGK ddPTM_HeLa_Curcumin_4h_R1 2 VAVVAGYGDVGK 12 0 P23526-2;P23526 P23526-2 AHCY Adenosylhomocysteinase 0 0 ; ; 185.14 9.87E-10 4684100 4986.7 4724.6 5107.4 4712.7 4856.2 5021.5 3677.3 4357.9 5143 4251.3 FALSE FALSE TRUE 4591.997433 5132.973372 5296.684737 4693.200096 4798.292987 3979.984296 3780.475141 5686.603649 4578.825767 4399.032359 1.043865346 1.166841467 1.20405678 1.06687101 1.090761012 0.904740855 0.859387891 1.292694208 1.040871127 1 12.1029705 -4.231064826 23.79260126 1.035013744 1.292695031 0.361420583 0.099614677 5616.310502 4399158.762 0.014446399 2.171090314 5.87E-05 4.231064826 0.257681287 VAYVSFGPHAGK ddPTM_HeLa_Curcumin_4h_R1 1 VAYVSFGPHAGK 12 0 P50914;E7EPB3 P50914 RPL14 60S ribosomal protein L14 0 0 120.77 0.00029456 2281600 1412.6 1026.5 1261.1 914.16 1933.4 3573.3 1776.5 1725.3 1615.5 1506.5 FALSE FALSE TRUE 1300.791219 1115.226086 1307.837475 910.3774481 1910.345468 2832.157301 1826.343809 2251.336028 1438.283692 1558.850763 0.834455261 0.715415556 0.838975421 0.584005519 1.22548323 1.816823886 1.171596315 1.444228069 0.922656438 1 10.6062671 -5.54234596 9.217426714 0.875736606 1.459423099 0.721110377 0.185025915 0.100054647 43.13723983 0.026895598 0.054343154 2.87E-06 5.54234596 0.583686493 VCEATYDT(ph)TLVEK ddPTM_HeLa_Curcumin_4h_R1 1 VCEATYDTTLVEK 13 0 A0A0D9SGK2;Q93096 A0A0D9SGK2 PTP4A1 Protein tyrosine phosphatase type IVA 1 1 0 VCEAT(0.163)Y(0.09)DT(0.373)T(0.373)LVEK 123.86 0.0062349 3132200 1079.3 287.68 913.58 656.38 842.93 251.26 509.41 779.84 559.67 510.1 TRUE FALSE FALSE 993.8722661 312.5457773 947.4380785 653.6640735 832.8786103 199.1458437 523.7026736 1017.609626 498.2756012 527.825937 1.882954581 0.592137967 1.794982042 1.238408399 1.577941802 0.377294539 0.992188214 1.927926528 0.944014999 1 9.043918435 VCEEIAIIPSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VCEEIAIIPSKK 12 1 H0YN88;A0A075B716;H3BNC9;P08708;H0YN73 H0YN88 RPS17 40S ribosomal protein S17 0 1 ; VCEEIAIIPSK(1)K;VCEEIAIIPSK(1)K 181.68 6.01E-10 5010100 4247.8 4315.5 3166.3 3371.9 5128 7103.9 4407.3 2933.8 6058.3 3533.6 FALSE TRUE FALSE 3911.582148 4688.512591 3283.645863 3357.947971 5066.851949 5630.471063 4530.956976 3828.302114 5393.719647 3656.392337 1.069792787 1.282278311 0.898056215 0.918377368 1.385751714 1.53989795 1.239187855 1.047016228 1.475147946 1 11.83620517 -5.755496555 24.99979075 1.036098755 1.31533196 0.126132258 0.205402345 104.9826301 441627.7937 0.022319939 0.043715079 1.76E-06 5.755496555 0.279233205 VCEEIAIIPSKK ddPTM_HeLa_Curcumin_4h_R1 2 VCEEIAIIPSKK 12 1 H0YN88;A0A075B716;H3BNC9;P08708;H0YN73 H0YN88 RPS17 40S ribosomal protein S17 0 0 ; ; 101.56 0.0022486 11180000 10171.9 6804.3 9141 8199.1 9063.4 10851.8 8769.2 7605.6 10216.7 8660.6 FALSE FALSE TRUE 9366.783382 7392.433373 9479.773501 8165.174297 8955.324874 8601.014355 9015.240151 9924.512428 9095.953571 8961.555205 1.04521851 0.824905187 1.057826826 0.911133627 0.999304771 0.959768049 1.005990584 1.107454253 1.014997214 1 13.12953341 VCENIPIVLCGNK ddPTM_HeLa_Curcumin_4h_R1 2 VCENIPIVLCGNK 13 0 F5H018;B5MDF5;J3KQE5;P62826;B4DV51 F5H018 RAN GTP-binding nuclear protein Ran 0 0 ; ; 197.31 1.30E-13 3329800 3366.96 2831.85 2853.21 2966.7 3318.56 4742.5 3386.58 2885.85 2743.54 2726 FALSE FALSE TRUE 3100.461563 3076.622496 2958.952473 2954.424581 3278.988339 3758.852041 3481.59832 3765.73238 2442.580526 2820.728297 1.099170582 1.090719194 1.049003009 1.047397789 1.162461604 1.332582101 1.234290564 1.335021308 0.865939668 1 11.46185199 -5.513077667 2.96002939 1.051792633 1.293731981 0.753500739 0.069652118 0.070770323 1.253429346 0.006804676 0.015730781 3.07E-06 5.513077667 0.241939348 VCNPIITK ddPTM_HeLa_Curcumin_4h_R1 2 VCNPIITK 8 0 P11142;E9PKE3;E9PNE6;A8K7Q2;E9PS65 P11142 HSPA8 Heat shock cognate 71 kDa protein 0 0 ; ; 132.08 0.0014607 36664000 15348.6 11345.4 13454.8 13693.1 14118.9 15755.7 13163 13411 13779.8 13123.1 FALSE FALSE TRUE 14133.74211 12326.04582 13953.44672 13636.44158 13950.54134 12487.79022 13532.31835 17499.95216 12268.19042 13579.12675 1.040843228 0.907720066 1.027565836 1.004220804 1.027351876 0.919631317 0.996552916 1.288739143 0.903459452 1 13.72910308 -4.260465227 24.97920522 1.004513272 1.288739233 0.733002614 0.054076295 27.45627439 703927.8159 0.006110525 0.0499004 5.49E-05 4.260465227 0.284225962 VCTIS(ph)PAPR ddPTM_HeLa_Curcumin_4h_R1 1 VCTISPAPR 9 0 O43439-2;O43439-5;O43439;O43439-4 O43439-2 CBFA2T2 Protein CBFA2T2 1 0 VCT(0.003)IS(0.997)PAPR 113.44 0.0080376 9965100 1557 1666.8 1728.1 1558 1773.6 2501.7 1587.9 474.28 1807 1608.7 TRUE FALSE FALSE 1433.761807 1810.870765 1792.144906 1551.553409 1752.450978 1982.81922 1632.4522 618.8857887 1608.776621 1664.602205 0.861323986 1.087869978 1.076620529 0.932086599 1.052774635 1.191167003 0.980686073 0.371792003 0.966463108 1 10.70096174 -4.261407907 24.99997164 0.980132748 0.371792044 0.805008039 0.09366714 0.993967393 786025.531 0.015223836 0.117369386 5.48E-05 4.261407907 -0.608340704 VCTLAIIDPGDSDIIR ddPTM_HeLa_Curcumin_4h_R1 1 VCTLAIIDPGDSDIIR 16 0 P62888;A0A0C4DH44;E5RI99;A0A0B4J213 P62888 RPL30 60S ribosomal protein L30 0 0 114.24 0.011136 32411000 2772.3 2466.6 2471.2 2304.8 2740.8 838.11 1177.4 1163.6 2194 1744.5 FALSE FALSE TRUE 2552.86953 2679.801913 2562.784846 2295.263348 2708.11775 664.2765386 1210.434675 1518.376283 1953.323689 1805.121245 1.414237153 1.484555079 1.419730034 1.271528632 1.50024147 0.367995524 0.670555886 0.841149196 1.082101102 1 10.81788003 -5.262838484 24.9999493 1.262697081 0.630965765 0.723102699 0.192320746 61.95645308 1107083.989 0.032735026 0.077133526 5.46E-06 5.262838484 -0.631731317 VDALHCPPAAVVTVTPS(ph)PEGVFSSLQAKPSPSPR ddPTM_HeLa_Curcumin_4h_R1 1 VDALHCPPAAVVTVTPSPEGVFSSLQAKPSPSPR 34 1 Q6UB99 Q6UB99 ANKRD11 Ankyrin repeat domain-containing protein 11 1 0 VDALHCPPAAVVT(0.001)VT(0.051)PS(0.851)PEGVFS(0.038)S(0.038)LQAKPS(0.009)PS(0.012)PR 80.554 4.95E-08 20339000 997.63 921.57 1007.4 1008.2 912.57 1203.3 919.08 482.29 1249.2 868.64 TRUE FALSE FALSE 918.6665328 1001.226404 1044.73513 1004.028336 901.6881988 953.722016 944.8669112 629.3380008 1112.165885 898.8251753 1.022074768 1.11392786 1.162334077 1.117045186 1.003185295 1.061076216 1.051224351 0.700178431 1.237355067 1 9.811896724 -4.260237928 24.57348304 1.039688227 0.700178291 0.623082824 0.08331758 33.61809031 687486.786 0.009015959 0.074525793 5.49E-05 4.260237928 -0.339509936 VDATADYICK ddPTM_HeLa_Curcumin_4h_R1 1 VDATADYICK 10 0 P53396;P53396-2 P53396 ACLY ATP-citrate synthase 0 0 96.342 0.01461 3468600 1418.4 1321.5 1491.2 1327.3 1481 1571.7 1066.6 1207 1463.6 1486.2 FALSE FALSE TRUE 1306.132143 1435.724572 1546.465184 1321.807984 1463.340042 1245.711703 1096.525925 1575.008744 1303.046742 1537.845339 0.849326073 0.933594904 1.005605144 0.859519453 0.951552152 0.810037051 0.71302744 1.024165892 0.847319759 1 10.5866947 -5.262712854 24.99806037 0.929565458 0.835471857 0.108305872 0.089775761 145.37431 2853706.744 0.012678524 0.029885425 5.46E-06 5.262712854 -0.0940936 VDATEESDLAQQYGVR ddPTM_HeLa_Curcumin_4h_R1 1 VDATEESDLAQQYGVR 16 0 P07237;H7BZ94;I3L3U6;I3NI03 P07237 P4HB Protein disulfide-isomerase 0 0 258.65 1.32E-39 3504100 700 721.58 793.63 703.96 956.44 1191.5 593.13 499.72 927.56 724.57 FALSE FALSE TRUE 644.5942614 783.9501599 823.0426259 701.0472 945.0350777 944.369469 609.7716315 652.0823276 825.8089886 749.7487536 0.859747026 1.045617157 1.097757912 0.935042835 1.260469021 1.259581246 0.813301294 0.86973446 1.101447631 1 9.550263408 -7.227996195 20.80006468 0.933769457 1.04656416 0 0.151608826 145.3955091 90428.19843 0.025188621 0.030846101 5.92E-08 7.227996195 0.112794703 VDCTAHSDVCSAQGVR ddPTM_HeLa_Curcumin_4h_R1 2 VDCTAHSDVCSAQGVR 16 0 Q8NBS9-2;Q8NBS9 Q8NBS9-2 TXNDC5 Thioredoxin domain-containing protein 5 0 0 ; ; 122.12 0.00012758 4876300 3541.1 2948.3 2985.4 3316.8 3179.1 4601.3 3090.9 2965.56 4703.2 3267.6 FALSE FALSE TRUE 3260.818198 3203.137915 3096.04155 3303.07596 3141.191309 3646.938513 3177.622335 3869.745592 4187.270727 3381.148857 0.96441131 0.947351936 0.915677387 0.976909358 0.929030765 1.078609274 0.939805513 1.14450613 1.238416557 1 11.72329782 VDCTANTNTCNK ddPTM_HeLa_Curcumin_4h_R1 2 VDCTANTNTCNK 12 0 H7BZJ3;P30101 H7BZJ3;P30101 PDIA3 Protein disulfide-isomerase A3 0 0 ; ; 303.31 1.39E-133 6888100 1601.37 1385.56 1689.68 1592.72 1536.91 1717.37 1250.76 1085.56 1481.05 1754.42 FALSE FALSE TRUE 1474.619875 1505.321632 1752.301027 1586.129747 1518.583352 1361.168103 1285.852959 1416.542247 1318.58252 1815.385964 0.812290005 0.829201978 0.965249849 0.873714889 0.836507157 0.749795432 0.708308307 0.780298115 0.726337289 1 10.82606059 -13.52287875 0.084652573 1.602956989 0.633415925 0 0.098413012 91.57429515 0.591420796 10.41520396 1.022206139 3.00E-14 13.52287875 -0.969541064 VDCTQHYELCSGNQVR ddPTM_HeLa_Curcumin_4h_R1 2 VDCTQHYELCSGNQVR 16 0 Q8NBS9-2;Q8NBS9 Q8NBS9-2 TXNDC5 Thioredoxin domain-containing protein 5 0 0 ; ; 120.7 0.00016242 4572900 1932.17 1739.59 2000.64 1821.34 1854.66 2320.9 1971.7 1451.36 2236.7 1822.9 FALSE FALSE TRUE 1779.236706 1889.952408 2074.785478 1813.803778 1832.544391 1839.519178 2027.020595 1893.872983 1991.339606 1886.245639 0.943268824 1.001965157 1.099955083 0.961594683 0.971530087 0.975227796 1.074632356 1.004043664 1.055715949 1 10.88130185 -7.014610928 24.92446782 0.97317905 1.014410669 0 0.0506378 945.2855276 1612543.732 0.007581197 0.009478282 9.67E-08 7.014610928 0.041231618 VDDDS(ph)LGEFPVTNSR ddPTM_HeLa_Curcumin_4h_R1 2 VDDDSLGEFPVTNSR 15 0 J3KMZ8;Q92785;Q92785-2 J3KMZ8 DPF2 Zinc finger protein ubi-d4 1 0 VDDDS(1)LGEFPVTNSR;VDDDS(1)LGEFPVTNSR ; 145.94 0.00048306 139007300 4524.8 3922.59 4307.27 4218.5 4834.9 5777.6 4313.3 2387.22 4458.1 4042.1 TRUE FALSE FALSE 4166.657305 4261.641201 4466.901215 4201.044965 4777.246975 4579.260633 4434.319589 3115.072389 3969.057584 4182.562674 0.996197219 1.018906717 1.067981896 1.004418891 1.142181803 1.09484567 1.060192025 0.744776022 0.948953523 1 12.03017144 -4.256869259 24.96381808 1.023757767 0.744775908 0.717288525 0.054477693 205.6885493 1123512.191 0.007820891 0.084308 5.54E-05 4.256869259 -0.278981859 VDDFLANEAK ddPTM_HeLa_Curcumin_4h_R1 2 VDDFLANEAK 10 0 P52209-2;P52209;K7EMN2;K7EM49;K7EPF6 P52209-2 PGD "6-phosphogluconate dehydrogenase, decarboxylating" 0 0 ; ; 152.54 3.59E-07 5071300 4394.8 3471.9 3964.3 4413.1 4731.9 4764.3 3967.4 3741.4 4365.4 3464.5 FALSE FALSE TRUE 4046.946943 3771.995566 4111.220445 4394.839762 4675.475183 3776.130475 4078.714566 4882.135637 3886.526542 3584.891117 1.128889779 1.052192505 1.146818777 1.225933959 1.304216789 1.053345932 1.13775131 1.361864413 1.084140749 1 11.80771359 -12.60452989 0.034600088 1.38E-07 1.857374598 0.376843514 0.086756932 496.0906554 1.622374236 65.485756 28.58795289 2.49E-13 12.60452989 1.85737446 VDDKPS(ph)SPGDSSK ddPTM_HeLa_Curcumin_4h_R1 2 VDDKPSSPGDSSK 13 1 C9J6K3;C9JM54;Q9HC52 C9J6K3;Q9HC52 CBX8 Chromobox protein homolog 8 1 0 VDDKPS(0.897)S(0.103)PGDSSK;VDDKPS(0.844)S(0.154)PGDS(0.002)SK ; 151.22 0.0047691 263286600 10640.6 8264.9 9206 10441.9 9186.1 10616.9 8459.9 5040.3 10867.5 9583.8 TRUE FALSE FALSE 9798.385282 8979.281128 9547.182458 10398.69418 9076.561757 8414.835263 8697.262025 6577.064267 9675.362439 9916.836337 0.98805556 0.905458235 0.962724616 1.048589876 0.915267879 0.848540298 0.877019821 0.663222024 0.975650108 1 13.27566423 -3.40514272 0.605380455 0.989925234 1.13E-11 0.805168578 0.045356186 2.423971687 0.287782446 0.007878559 2.127888448 0.000393421 3.40514272 -0.989925234 VDDKPSS(ph)PGDSSK ddPTM_HeLa_Curcumin_4h_R1 1 VDDKPSSPGDSSK 13 1 C9J6K3;C9JM54;Q9HC52 C9J6K3;Q9HC52 CBX8 Chromobox protein homolog 8 1 0 VDDKPS(0.01)S(0.981)PGDS(0.008)S(0.001)K 154.13 0.0039813 22654000 4076.6 3383.8 3084.3 3574.8 3488.1 4174.1 2842.8 1750.8 3865.2 3243.3 TRUE FALSE FALSE 3753.932808 3676.280594 3198.606871 3560.008425 3446.506686 3308.344608 2922.561317 2284.61086 3441.19723 3356.004434 1.118572065 1.095433772 0.953099716 1.06078776 1.026967262 0.985798641 0.870845487 0.680753231 1.025385186 1 11.71252891 -3.961042719 0.911977449 1.054035836 0.270162909 0.864959743 0.04438873 0.991238021 0.428721097 0.008476395 0.875841702 0.000109385 3.961042719 -0.783872927 VDDLSS(ph)SPTSSPER ddPTM_HeLa_Curcumin_4h_R1 2 VDDLSSSPTSSPER 14 0 Q96JK2-2;Q96JK2-3;Q96JK2 Q96JK2-2 DCAF5 DDB1- and CUL4-associated factor 5 1 0 VDDLS(0.052)S(0.471)S(0.471)PT(0.006)SSPER;VDDLS(0.064)S(0.419)S(0.419)PT(0.082)S(0.016)SPER ; 155.14 0.00039905 10663000 3959.1 3653.2 4128.1 3885.1 3895.5 4104.5 3072.1 2969.7 3711.3 3202.9 TRUE FALSE FALSE 3645.733057 3968.96633 4281.091017 3869.024486 3849.048707 3253.180433 3158.294858 3875.147859 3304.179675 3314.200537 1.100033935 1.197563722 1.291741695 1.16740808 1.161380751 0.981588289 0.952958285 1.169255697 0.996976387 1 11.69444518 -3.951073159 14.47248959 1.080329091 1.62292202 0.028188347 0.105996774 1427198.697 12549837.49 0.016114094 20938116.14 0.000111925 3.951073159 0.542592929 VDDS(ph)PSTSGGSSDGDQR ddPTM_HeLa_Curcumin_4h_R1 1 VDDSPSTSGGSSDGDQR 17 0 F8WF15;F8W8F0;C9J180;Q96LR5 F8WF15 UBE2E2 Ubiquitin-conjugating enzyme E2 E2 1 0 VDDS(0.701)PS(0.27)T(0.029)S(0.001)GGSSDGDQR 207.21 7.95E-11 4890200 1796.7 1235.1 1299.4 1376.5 1955.6 1837.7 1694.5 637.48 1286.4 1326.6 TRUE FALSE FALSE 1654.489299 1341.856541 1347.556907 1370.804408 1932.280747 1456.540305 1742.043109 831.8447174 1145.285138 1372.699251 1.205281709 0.977531341 0.981684011 0.998619622 1.407650471 1.061077511 1.269063932 0.605991966 0.834330708 1 10.42279986 -4.249251905 24.6614123 1.103475239 0.605991595 0.436945637 0.160293454 969.7026519 1962155.73 0.019237271 0.431115309 5.63E-05 4.249251905 -0.497483644 VDDSPS(ph)TSGGSSDGDQR ddPTM_HeLa_Curcumin_4h_R1 1 VDDSPSTSGGSSDGDQR 17 0 F8WF15;F8W8F0;C9J180;Q96LR5 F8WF15 UBE2E2 Ubiquitin-conjugating enzyme E2 E2 1 0 VDDS(0.272)PS(0.652)T(0.073)S(0.002)GGSSDGDQR 172.26 4.77E-05 7525600 880.19 989.23 913.83 932.49 1276 1279.6 1027 626.97 662.14 704.14 TRUE FALSE FALSE 810.5220327 1074.734633 947.6973437 928.6316035 1260.784533 1014.196536 1055.814856 818.1302668 589.5048986 728.6088126 1.112424141 1.47505028 1.30069432 1.274526999 1.730399786 1.391963038 1.449083291 1.12286628 0.809082855 1 9.509000634 -7.38171899 3.847634064 1.047439824 1.399148153 0.557021496 0.167536423 0.132692815 3.376558921 0.025992068 0.029488554 4.15E-08 7.38171899 0.351708329 VDDSPSTSGGS(ph)SDGDQR ddPTM_HeLa_Curcumin_4h_R1 1 VDDSPSTSGGSSDGDQR 17 0 F8WF15;F8W8F0;C9J180;Q96LR5 F8WF15 UBE2E2 Ubiquitin-conjugating enzyme E2 E2 1 0 VDDSPSTSGGS(0.5)S(0.5)DGDQR 257.46 1.05E-40 17439000 2572.2 2287.3 2674.4 2434.2 3201.1 2727.5 2252 1613.9 2054.6 2034.6 TRUE FALSE FALSE 2368.607656 2485.00402 2773.515617 2424.127925 3162.928973 2161.785755 2315.185059 2105.970681 1829.21552 2105.302199 1.125067773 1.180355021 1.317395488 1.151439412 1.502363402 1.026829192 1.09969251 1.000317523 0.86886126 1 11.03981162 -8.222579183 0.908899981 1.019183183 1.186288014 0.270870627 0.145459555 0.593072947 1.03724599 0.045298109 0.030203813 5.99E-09 8.222579183 0.167104831 VDDSPSTSGGSS(ph)DGDQR ddPTM_HeLa_Curcumin_4h_R1 1 VDDSPSTSGGSSDGDQR 17 0 F8WF15;F8W8F0;C9J180;Q96LR5 F8WF15 UBE2E2 Ubiquitin-conjugating enzyme E2 E2 1 0 VDDSPSTSGGS(0.051)S(0.949)DGDQR 212.35 8.27E-12 13318000 1853 2090.6 1936.7 1939.4 2634.7 2309 2140.9 1111.7 1974.2 1651.3 TRUE FALSE FALSE 1706.333095 2271.302148 2008.475806 1931.375277 2603.282923 1830.087372 2200.967892 1450.652212 1757.635199 1708.682552 0.998624989 1.329270991 1.175452868 1.130330075 1.523561483 1.071051712 1.288108133 0.84898872 1.028649352 1 10.73866868 -7.28818287 23.19005617 0.999350648 1.20341523 0.207177639 0.166020223 286.7637488 248660.2965 0.02602899 0.02977203 5.15E-08 7.28818287 0.204064582 VDDSSGSIGRR ddPTM_HeLa_Curcumin_4h_R1 3 VDDSSGSIGRR 11 1 P41250 P41250 GARS Glycine--tRNA ligase 0 0 ;; ;; 136.49 0.0018932 5589780 2159 2036.79 1755.4 2125.42 1986.51 2715.3 1934.84 1838.5 2457.18 2183.48 FALSE FALSE TRUE 1988.112872 2212.841052 1820.456668 2116.625575 1962.822166 2152.116172 1989.126403 2399.050187 2187.633502 2259.355767 0.879946797 0.979412399 0.805741484 0.93682704 0.868753029 0.952535321 0.88039539 1.061829315 0.968255435 1 11.14169575 -9.465900465 1.160179055 1.000765811 0.913584874 0.112994482 0.067114927 0.620737186 1.473325934 0.0440441 0.010472102 3.42E-10 9.465900465 -0.087180938 VTSSVPLPSGSTSS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 3 VTSSVPLPSGSTSSPGR 17 0 Q15036-2;Q15036 Q15036-2 SNX17 Sorting nexin-17 1 0 VTSSVPLPSGSTS(0.021)S(0.979)PGR;VTSSVPLPSGSTS(0.022)S(0.978)PGR;VTSSVPLPSGST(0.001)S(0.028)S(0.971)PGR ;; 315.47 4.22E-112 257041000 13827.2 14104.4 13485.7 14508.3 14215.8 13274.1 11296.8 4695.9 13543.1 12232.7 TRUE FALSE FALSE 12732.76253 15323.52149 13985.49191 14448.2685 14046.28587 10520.90203 11613.7578 6127.658293 12057.45581 12657.78541 1.005923399 1.210600511 1.104892479 1.141453108 1.10969537 0.831180312 0.917518936 0.484101926 0.952572304 1 13.62773739 -4.017646665 1.189877838 1.039323874 5.71E-16 0.763288366 0.095498354 0.974225217 0.778664642 0.014698274 1.43194672 9.60E-05 4.017646665 -1.039323874 down VDEGAGDSAAVASGGAQT(ph)LALAGSPAPSGHPK ddPTM_HeLa_Curcumin_4h_R1 1 VDEGAGDSAAVASGGAQTLALAGSPAPSGHPK 32 0 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 0 VDEGAGDSAAVAS(0.007)GGAQT(0.534)LALAGS(0.448)PAPS(0.011)GHPK 98.151 7.52E-09 8552900 1051 976.2 850.49 1160 1315.6 2101.1 1511.2 568.02 1435.2 1286.1 TRUE FALSE FALSE 967.812241 1060.578378 882.0099076 1155.200227 1299.912329 1665.308176 1553.600205 741.2066832 1277.762151 1330.791879 0.727245376 0.796952848 0.662770732 0.868054761 0.976796109 1.251366349 1.167425372 0.556966641 0.960151749 1 10.37806925 -5.723656031 4.340328676 0.844000407 1.023702159 0.121114243 0.194361035 0.317682085 13.09049579 0.029648062 0.059459352 1.89E-06 5.723656031 0.179701752 VDEGAGDSAAVASGGAQTLALAGS(ph)PAPSGHPK ddPTM_HeLa_Curcumin_4h_R1 1 VDEGAGDSAAVASGGAQTLALAGSPAPSGHPK 32 0 Q9NZT2-2;Q9NZT2;A0A0A0MRN5 Q9NZT2-2 OGFR Opioid growth factor receptor 1 0 VDEGAGDSAAVASGGAQT(0.007)LALAGS(0.984)PAPS(0.009)GHPK 124.96 1.69E-13 21386000 1653.8 1334.7 1450.4 1506.7 2063.2 3273.7 1884.5 806.79 2009.3 1534.7 TRUE FALSE FALSE 1522.899985 1450.065521 1504.1531 1500.465675 2038.597688 2594.697718 1937.373998 1052.776557 1788.884817 1588.030711 0.958986482 0.913121838 0.947181367 0.944859356 1.283726866 1.63390903 1.219985221 0.662944709 1.126479989 1 10.6330231 -5.764962452 24.93585782 0.969532229 1.232542284 0.174223731 0.227656932 95.17332508 673631.2123 0.032177861 0.060059382 1.72E-06 5.764962452 0.263010055 VDENENCSSLGS(ph)PSEPPQTLDLVR ddPTM_HeLa_Curcumin_4h_R1 2 VDENENCSSLGSPSEPPQTLDLVR 24 0 A0A0C4DGQ6;Q96P16-3;Q96P16 A0A0C4DGQ6 RPRD1A Regulation of nuclear pre-mRNA domain-containing protein 1A 1 0 VDENENCSS(0.001)LGS(0.977)PS(0.022)EPPQTLDLVR;VDENENCSSLGS(0.927)PS(0.073)EPPQTLDLVR ; 170.83 3.44E-10 11541300 3369.3 3168.7 2186.96 3873.5 2760.5 1660.12 1659.91 2015.07 4053.6 2928.5 TRUE FALSE FALSE 3102.61635 3442.588309 2268.010661 3857.472483 2727.58284 1315.792399 1706.482607 2629.455567 3608.930222 3030.265157 1.023876192 1.136068341 0.748452873 1.272981829 0.900113587 0.434216918 0.563146299 0.867731182 1.190961858 1 11.56522832 -5.457260704 6.442118983 1.019107082 0.620381007 0.572932609 0.167555651 0.118628595 9.379393232 0.020519447 0.045973216 3.49E-06 5.457260704 -0.398726075 VDENMT(ph)ASTYSLNKIPER ddPTM_HeLa_Curcumin_4h_R1 1 VDENMTASTYSLNKIPER 18 1 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4;J3KRP9 Q9HCD6 TANC2 Protein TANC2 1 0 VDENMT(0.577)AS(0.004)T(0.043)YS(0.376)LNKIPER 67.227 0.0093919 9772000 1484.5 1374.2 1575.2 1713 1891 2809.8 2224.1 1089.8 1589.1 1905.7 TRUE FALSE FALSE 1367.000259 1492.979725 1633.578298 1705.91206 1868.45106 2227.015807 2286.50226 1422.075003 1414.779706 1971.922933 0.693232091 0.757118698 0.828418936 0.865100776 0.947527425 1.129362497 1.15952922 0.721161552 0.717461967 1 10.94538745 -5.653611303 3.298920714 0.841466093 1.021136448 0.273315684 0.138443806 0.294448141 6.320700816 0.023097522 0.048723022 2.22E-06 5.653611303 0.179670355 VDENMTAS(ph)TYSLNK ddPTM_HeLa_Curcumin_4h_R1 1 VDENMTASTYSLNK 14 0 Q9HCD6;Q9HCD6-2;Q9HCD6-3;Q9HCD6-4;J3KRP9 Q9HCD6 TANC2 Protein TANC2 1 0 VDENMT(0.002)AS(0.318)T(0.318)Y(0.215)S(0.147)LNK 97.813 0.0062626 27776000 2555.4 1940.3 2124.4 1950.3 2010.5 2362.9 1786.2 2152 2382.7 2134.7 TRUE FALSE FALSE 2353.137394 2108.010886 2203.132133 1942.230175 1986.526101 1872.807905 1836.315965 2808.134893 2121.323771 2208.880666 1.065307615 0.954334437 0.997397536 0.879282528 0.89933609 0.847853817 0.83133326 1.271293165 0.960361419 1 11.10909976 -6.898205655 1.983516657 1.030073399 0.934871537 0.013258331 0.121341938 0.523870378 4.171675535 0.019641973 0.026735645 1.26E-07 6.898205655 -0.095201862 VDFNVPMK ddPTM_HeLa_Curcumin_4h_R1 2 VDFNVPMK 8 0 P00558;P07205 P00558 PGK1;PGK2 Phosphoglycerate kinase 1;Phosphoglycerate kinase 2 0 0 ; ; 106.36 0.0085259 18477700 12519.9 9455 9940.6 10445.3 11084.1 12982.8 10963.8 10002.7 11439.9 9508.9 FALSE FALSE TRUE 11528.9367 10272.24807 10309.00738 10402.08012 10951.92935 10290.02093 11271.41472 13052.47718 10184.97159 9839.333567 1.171719266 1.043998356 1.047734311 1.057193563 1.113076335 1.045804664 1.14554656 1.326561102 1.035128195 1 13.26434489 -4.308777564 2.631146399 1.076403192 1.363455626 0.742957718 0.046341331 0.225857452 2.165223643 0.008968235 0.134948056 4.91E-05 4.308777564 0.287052433 VDGANVALKDSDQVAQSDGEES(ph)PAAEEQLLGEHIK ddPTM_HeLa_Curcumin_4h_R1 1 VDGANVALKDSDQVAQSDGEESPAAEEQLLGEHIK 35 1 D6REX3;O94979-3;O94979-9;O94979-2;O94979;O94979-8;D6RHZ5 D6REX3 SEC31A Protein transport protein Sec31A 1 0 VDGANVALKDS(0.001)DQVAQS(0.462)DGEES(0.537)PAAEEQLLGEHIK 55.033 0.00034795 6923700 2743.8 2728.5 2265.8 2808.4 2752.4 3382.2 2203.8 1812.1 3037.7 2431.2 TRUE FALSE FALSE 2526.625335 2964.339382 2349.772541 2796.779585 2719.579428 2680.693595 2265.632697 2364.600948 2704.47191 2515.684019 1.004349241 1.178343289 0.934049159 1.111737231 1.081049689 1.06559233 0.900603049 0.939943542 1.075044358 1 11.29673501 -4.755097871 24.99652408 1.026710372 0.920273261 0.321973336 0.068990046 143.7447238 566586.3127 0.009295295 0.033135927 1.76E-05 4.755097871 -0.106437111 VDGIPNDS(ph)S(ph)DSEMEDKTTANLAALK ddPTM_HeLa_Curcumin_4h_R1 1 VDGIPNDSSDSEMEDKTTANLAALK 25 1 Q9H6S0 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 2 0 VDGIPNDS(0.534)S(0.534)DS(0.516)EMEDKT(0.208)T(0.208)ANLAALK 42.384 0.0087483 0 690.21 704.11 853.03 907.01 909.82 1133.1 854.42 521.77 844.09 905.2 TRUE FALSE FALSE 635.5791502 764.9701309 884.6440422 903.2570329 898.9709907 898.0822873 878.3927256 680.8552711 751.4954388 936.6556326 0.678562246 0.816703711 0.944470958 0.964342712 0.959766812 0.958818007 0.937796875 0.726900311 0.802317749 1 9.871374919 -6.760142051 24.99962447 0.841605788 0.922591433 0.158732039 0.098629646 74.9450528 1444172.35 0.02160171 0.029602249 1.74E-07 6.760142051 0.080985645 VDGIPNDS(ph)SDSEMEDK ddPTM_HeLa_Curcumin_4h_R1 3 VDGIPNDSSDSEMEDK 16 0 Q9H6S0 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 1 0 VDGIPNDS(0.476)S(0.476)DS(0.048)EMEDK;VDGIPNDS(0.484)S(0.484)DS(0.033)EMEDK;VDGIPNDS(0.462)S(0.462)DS(0.075)EMEDK ;; 119.04 0.00099815 26719600 6261.19 5559.7 6606.7 5702.4 7422.4 7603.2 6803.18 4755.09 5635.21 5704.81 TRUE FALSE FALSE 5765.610205 6040.255694 6851.550114 5678.80498 7333.892728 6026.210614 6994.058921 6204.895051 5017.041562 5903.051723 0.97671687 1.023242888 1.160679329 0.962011727 1.24239005 1.020863597 1.184820877 1.051133438 0.849906421 1 12.52724527 -6.939956685 6.183961679 0.989504917 1.103213102 0.36938031 0.088634389 0.157015301 11.95087843 0.01090365 0.014348393 1.15E-07 6.939956685 0.113708186 VDGIPNDSS(ph)DSEMEDK ddPTM_HeLa_Curcumin_4h_R1 1 VDGIPNDSSDSEMEDK 16 0 Q9H6S0 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 1 0 VDGIPNDS(0.159)S(0.686)DS(0.155)EMEDK 174.78 4.81E-05 5085500 2328.8 2850.3 2764.3 2587.4 2829.2 2876.8 2632.5 1874.4 2687.7 2000.6 TRUE FALSE FALSE 2144.473023 3096.667231 2866.74739 2576.694024 2795.463638 2280.119252 2706.360865 2445.895931 2392.866034 2070.120701 1.035916902 1.495887283 1.384821372 1.244707143 1.350386785 1.10144266 1.307344477 1.181523343 1.155906529 1 11.01549917 -7.387184815 8.315527057 1.015855166 1.291613351 0.45880656 0.111596094 0.142004573 9.00291503 0.017416872 0.019876667 4.10E-08 7.387184815 0.275758185 VDGIPNDSSDS(ph)EMEDK ddPTM_HeLa_Curcumin_4h_R1 1 VDGIPNDSSDSEMEDK 16 0 Q9H6S0 Q9H6S0 YTHDC2 Probable ATP-dependent RNA helicase YTHDC2 1 0 VDGIPNDS(0.001)S(0.005)DS(0.993)EMEDK 119.54 0.0011279 4855200 1304.9 1439.3 1511.3 1245 1591.6 1803.4 1442.5 1011.7 1169.5 1005.4 TRUE FALSE FALSE 1201.615788 1563.706679 1567.310107 1239.84852 1572.62121 1429.354511 1482.972668 1320.162673 1041.208776 1040.337575 1.155024885 1.503076228 1.506539939 1.191775198 1.511645111 1.373933371 1.425472561 1.268975287 1.000837421 1 10.02283602 -7.473732786 3.071719127 1.062103154 1.397648054 0.700636867 0.104201202 0.104538218 1.91067324 0.018972406 0.020936873 3.36E-08 7.473732786 0.3355449 VDHGAEIITQS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 5 VDHGAEIITQSPGR 14 0 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 1 0 VDHGAEIITQS(1)PGR;VDHGAEIIT(0.013)QS(0.987)PGR;VDHGAEIITQS(1)PGR;VDHGAEIITQS(1)PGR;VDHGAEIITQS(1)PGR ;;;; 218.34 5.83E-14 648174000 11586.1 8884.69 9808.02 9321 10100.9 12670 8718.93 5375.15 11314.9 9377.6 TRUE FALSE FALSE 10669.04796 9652.643014 10171.51385 9282.432172 9980.453365 10042.09918 8963.55971 7014.008491 10073.68378 9703.470902 1.09950842 0.994761886 1.048234591 0.956609472 1.028544679 1.034897644 0.923747781 0.72283501 1.038152624 1 13.24428517 -4.269792602 1.739011813 1.036831662 0.616158827 0.857353967 0.037375525 0.281467339 0.837403912 0.006659415 0.194441719 5.37E-05 4.269792602 -0.420672835 VDHGAEIITQS(ph)PGRS(ph)S(ph)VASPR ddPTM_HeLa_Curcumin_4h_R1 1 VDHGAEIITQSPGRSSVASPR 21 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 3 0 VDHGAEIIT(0.007)QS(0.984)PGRS(0.77)S(0.77)VAS(0.468)PR 56.131 0.011256 13268000 3255.1 2938.1 2948.3 2856.6 2846.8 2478.5 1911.7 1333.2 3413.9 2752.7 TRUE FALSE FALSE 2997.4554 3192.056272 3057.566592 2844.780146 2812.853769 1964.431162 1965.337157 1739.686543 3039.403711 2848.35612 1.05234573 1.120666145 1.073449549 0.998744548 0.987535845 0.689671894 0.689989971 0.610768622 1.06707293 1 11.47591382 -5.271523304 2.699556453 1.035544629 0.651038745 0.950171628 0.039986567 0.047485141 0.682720895 0.006468045 0.017813998 5.35E-06 5.271523304 -0.384505885 VDHGAEIITQSPGRS(ph)S(ph)VAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 VDHGAEIITQSPGRSSVASPR 21 1 A0A669KB77;P11137-3;P11137;P11137-2;P11137-4 A0A669KB77 MAP2 Microtubule-associated protein 2 3 0 VDHGAEIIT(0.102)QS(0.362)PGRS(0.828)S(0.868)VAS(0.84)PR 55.907 0.011446 12996000 2195.2 2193.3 2241.7 2158.7 1718.3 2142.1 1342.7 992.57 2262 1753.8 TRUE FALSE FALSE 2021.447604 2382.879079 2324.779374 2149.767871 1697.810395 1697.804314 1380.372548 1295.200024 2013.864259 1814.744419 1.113902091 1.313065936 1.281050571 1.18461192 0.935564467 0.935561116 0.76064295 0.71370933 1.109723351 1 10.82555066 -5.051546077 1.465446767 1.100754076 0.714922062 0.700791582 0.105438163 0.264122684 1.010537291 0.019374359 0.095480477 8.88E-06 5.051546077 -0.385832014 VDIAEGR ddPTM_HeLa_Curcumin_4h_R1 1 VDIAEGR 7 0 Q15056;Q15056-2 Q15056 EIF4H Eukaryotic translation initiation factor 4H 0 0 104.45 0.017543 5478500 8341.5 6852 7380.2 7557.7 7580.8 8837.4 7644.8 7183 7570 6998.9 FALSE FALSE TRUE 7681.261473 7444.256348 7653.716704 7526.42824 7490.403911 7004.423622 7859.292513 9373.063634 6739.589939 7242.111254 1.060638425 1.027912454 1.056835008 1.039258854 1.034284568 0.967179787 1.085221179 1.294244635 0.930611213 1 12.82219462 -4.29697856 3.317266634 1.028925123 1.320140879 0.806392635 0.040690067 0.068241025 1.238656503 0.004153268 0.04791088 5.05E-05 4.29697856 0.291215755 VDIDAPDVDVHGPDWHLK ddPTM_HeLa_Curcumin_4h_R1 3 VDIDAPDVDVHGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ;; ;; 127.29 5.83E-05 164713700 22352.5 18341.9 21245.9 20516 20653.2 25057 18975.42 19265.37 24416.96 19138.81 FALSE FALSE TRUE 20583.27604 19927.29211 22033.29174 20431.11023 20406.92408 19859.89575 19507.81922 25139.29263 21738.48058 19803.88222 1.039355608 1.006231601 1.112574368 1.031671972 1.030450689 1.002828411 0.985050254 1.269412348 1.097687834 1 14.27349565 -4.255991028 24.98669579 1.023309664 1.269412452 0.746439766 0.040739371 175.7143498 805818.8429 0.004728212 0.05399369 5.55E-05 4.255991028 0.246102789 VDIDAPDVEVHDPDWHLK ddPTM_HeLa_Curcumin_4h_R1 4 VDIDAPDVEVHDPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ;;; ;;; 156.57 1.42E-05 78993100 25156.1 19957.1 21818.7 24512.2 22519.5 27104.5 20021.2 20955.9 26663.1 22454.3 FALSE FALSE TRUE 23164.96814 21682.1028 22627.32022 24410.77501 22250.96967 21482.72117 20582.94099 27345.25744 23738.22464 23234.58525 0.997003729 0.933182261 0.973863745 1.050622369 0.957665886 0.924601018 0.885875119 1.176920403 1.02167628 1 14.50398627 -7.482044793 24.84251927 0.998678156 0.979678809 0.006621546 0.076799026 2060.17609 1253377.218 0.012257233 0.01384935 3.30E-08 7.482044793 -0.018999347 VDIDAPDVS(ph)IEGPDAK ddPTM_HeLa_Curcumin_4h_R1 2 VDIDAPDVSIEGPDAK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VDIDAPDVS(1)IEGPDAK;VDIDAPDVS(1)IEGPDAK ; 119.46 0.00097253 6064000 5723.7 4066 4819 4786 5074.9 7152.7 4948.1 4115.9 5045.1 4342.5 TRUE FALSE FALSE 5270.663105 4417.446922 4997.596379 4766.1968 5014.385132 5669.149392 5086.930369 5370.818963 4491.665152 4493.401552 1.172978432 0.983096407 1.112207828 1.060710187 1.11594414 1.261660977 1.132088978 1.195267973 0.999613567 1 12.13359228 -13.52287875 0.202340079 0.387992361 1.161241016 0.400343942 0.068014584 46.69003666 0.570002889 11.43631785 0.073359127 3.00E-14 13.52287875 0.773248655 VDIDAPDVSIEGPDAK ddPTM_HeLa_Curcumin_4h_R1 1 VDIDAPDVSIEGPDAK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 126.5 0.0045731 3587100 3677.6 2962.5 3591.3 3468.5 3503.1 3832.9 2976.8 3330.5 3603 3116.8 FALSE FALSE TRUE 3386.514079 3218.565299 3724.396737 3454.148266 3461.32782 3037.913334 3060.320996 4345.954118 3207.759914 3225.108568 1.050046536 0.997971148 1.154812825 1.071017671 1.073243814 0.94195692 0.948904799 1.347537308 0.994620754 1 11.65513201 -4.252563324 24.8965121 1.028392692 1.347537481 0.71588547 0.06077918 460.6325089 1292002.235 0.00846695 0.135943639 5.59E-05 4.252563324 0.319144789 RPSTSQTVST(ph)PAPVPVIESTEAIEAK ddPTM_HeLa_Curcumin_4h_R1 3 RPSTSQTVSTPAPVPVIESTEAIEAK 26 1 P12270;P12270-2 P12270 TPR Nucleoprotein TPR 1 0 RPS(0.028)T(0.028)S(0.028)QT(0.022)VS(0.109)T(0.785)PAPVPVIESTEAIEAK;RPS(0.003)T(0.003)S(0.003)QT(0.009)VS(0.075)T(0.908)PAPVPVIESTEAIEAK;RPS(0.024)T(0.024)S(0.024)QT(0.029)VS(0.208)T(0.686)PAPVPVIES(0.002)T(0.001)EAIEAK ;; 79.299 5.96E-05 47577900 4677.4 3898.1 4679.4 4845.6 4923.5 6317.8 6308.4 7348.4 4922.1 4184.4 TRUE FALSE FALSE 4307.178854 4235.034394 4852.82268 4825.550191 4864.790478 5007.417064 6485.396726 9588.893332 4382.157944 4329.807589 0.994773732 0.978111454 1.120794073 1.114495296 1.123558121 1.15649875 1.497848713 2.21462343 1.012090689 1 12.0800872 -1 0.723416699 1.006609598 182.9546765 0.982534789 0.047679372 27.17226092 0.122698643 0.008466682 8036.602877 0.1 1 181.9480669 up DS(ph)LSPVLHPSDLILTR ddPTM_HeLa_Curcumin_4h_R1 1 DSLSPVLHPSDLILTR 16 0 Q9HCN4-3;Q9HCN4-2;Q9HCN4-4;Q9HCN4;Q9HCN4-5 Q9HCN4-3 GPN1 GPN-loop GTPase 1 1 0 DS(0.599)LS(0.4)PVLHPS(0.002)DLILTR 175.26 4.01E-05 9801300 750.23 771.97 764.72 746.67 936.18 2033.1 1074.3 1794.8 919.29 586.6 TRUE FALSE FALSE 690.8485039 838.695647 793.0611959 743.5804774 925.0166649 1611.412142 1104.441967 2342.026258 818.446187 606.9843063 1.138165347 1.381741897 1.306559639 1.225040696 1.523954829 2.654783864 1.81955605 3.858462621 1.348381133 1 9.245515406 -1 0.430254219 1.05547784 52.19016612 0.822295599 0.353203454 17.13055206 0.192224543 0.068683457 766.7015979 0.1 1 51.13468828 up VDIDTPDIDIHGPEGK ddPTM_HeLa_Curcumin_4h_R1 1 VDIDTPDIDIHGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 130.02 0.00024327 0 3097.8 2824.6 2947.3 2894.6 2952.1 3621.9 2896.6 2902 3139.3 2586.9 FALSE FALSE TRUE 2852.605861 3068.745838 3056.529531 2882.622912 2916.898136 2870.677113 2977.8708 3786.806441 2794.926644 2676.794582 1.06567978 1.146425601 1.141861819 1.076893584 1.089698162 1.072430859 1.1124764 1.414679507 1.044131912 1 11.38629072 -1.705815014 1.142719661 1.054723101 153.6346613 0.81392754 0.046476459 235.2120877 0.937203556 0.008777328 93486.96295 0.019687247 1.705815014 152.5799382 VDIDVPDVDVQGPDWHLK ddPTM_HeLa_Curcumin_4h_R1 2 VDIDVPDVDVQGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 130.77 0.00018553 87678000 6472.3 5130.1 5129.9 5673.1 5050 6694.7 4658.2 5357.8 5807.2 5138.6 FALSE FALSE TRUE 5960.010625 5573.522985 5320.018607 5649.626215 4989.782048 5306.143755 4788.896555 6991.368556 5170.164689 5317.165968 1.120899867 1.048213093 1.000536496 1.062525836 0.93842887 0.997927051 0.900648312 1.314867469 0.972353453 1 12.37644178 -6.983875297 22.15121938 1.05853712 1.024711707 0 0.111580427 255.393387 350838.1271 0.016995906 0.022329984 1.04E-07 6.983875297 -0.033825413 VDIDVPDVNIEGPDAK ddPTM_HeLa_Curcumin_4h_R1 2 VDIDVPDVNIEGPDAK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 183.96 7.60E-05 29542000 11005.8 10126 10889.8 10697.4 11769.8 14407.3 11045.1 11005.1 12020.3 9569.5 FALSE FALSE TRUE 10134.67932 11001.24632 11293.38557 10653.13699 11629.45282 11419.06358 11354.99578 14360.50433 10701.70316 9902.039413 1.02349414 1.111008133 1.14051107 1.075852817 1.174450266 1.153203204 1.146733042 1.450257238 1.08075748 1 13.27350998 -1 0.300637934 1.005001418 4.127372262 0.725136222 0.061836335 15.35038195 0.196374926 0.021071526 26.15461605 0.1 1 3.122370844 ELEAIFGRPVVDGEEGEPHS(ph)ISPR ddPTM_HeLa_Curcumin_4h_R1 5 ELEAIFGRPVVDGEEGEPHSISPR 24 1 P36507;G5E9C7 P36507 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 1 0 ELEAIFGRPVVDGEEGEPHS(0.5)IS(0.5)PR;ELEAIFGRPVVDGEEGEPHS(0.747)IS(0.253)PR;ELEAIFGRPVVDGEEGEPHS(0.779)IS(0.221)PR;ELEAIFGRPVVDGEEGEPHS(0.776)IS(0.224)PR;ELEAIFGRPVVDGEEGEPHS(0.714)IS(0.286)PR ;;;; 113.87 4.28E-07 65350700 5174.17 5356.88 4579.78 4566.69 4655.22 9521.81 5623.16 7621.28 5522.86 4314.15 TRUE FALSE FALSE 4764.628985 5819.904837 4749.510676 4547.794247 4599.709542 7546.879273 5780.930736 9944.973188 4917.016076 4464.066391 1.067329329 1.303722733 1.063942661 1.018755961 1.030385559 1.690584013 1.294992106 2.227783441 1.101465714 1 12.12414277 -1 0.588083695 1.045228273 65.83851532 0.771014652 0.179072913 44.79654118 0.332181104 0.029293629 3728.314981 0.1 1 64.79328705 up VDIEGPDVNIEGPEGK ddPTM_HeLa_Curcumin_4h_R1 2 VDIEGPDVNIEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 238.47 4.67E-29 14903300 6811.5 5209.5 5948.3 6030 5899.9 6885.2 5506.8 5687.7 6543 5161.4 FALSE FALSE TRUE 6272.362588 5659.785967 6168.749231 6005.049458 5829.547546 5457.131908 5661.305987 7421.853547 5825.24927 5340.758266 1.174432969 1.059734533 1.155032474 1.124381438 1.091520577 1.021789723 1.060019141 1.389662886 1.090715771 1 12.38282887 -9.445449733 1.089744758 0.997461799 1.129403271 0.08493474 0.100220381 0.677244381 1.393255805 0.070373289 0.016204225 3.59E-10 9.445449733 0.131941472 LSPLPPGSPGS(ph)AAR ddPTM_HeLa_Curcumin_4h_R1 1 LSPLPPGSPGSAAR 14 0 Q6ZN18-2;Q6ZN18 Q6ZN18-2 AEBP2 Zinc finger protein AEBP2 1 0 LSPLPPGS(0.037)PGS(0.963)AAR 142.95 0.00069264 15732000 1948.8 1425.8 1867.2 2015.9 2272 3802.1 2469.1 3153.6 2085.9 1660.7 TRUE FALSE FALSE 1794.550424 1549.039799 1936.400075 2007.55874 2244.907884 3013.501602 2538.376301 4115.118123 1857.081989 1718.409201 1.044309133 0.901438259 1.126856207 1.168265823 1.306387258 1.753657743 1.477166381 2.394725377 1.08069835 1 10.74685791 -1 0.426153377 0.997839237 26.66663474 0.886847019 0.144248217 13.89048412 0.157050663 0.029493468 308.2764912 0.1 1 25.6687955 up VDINAPDVDVQGPDWHLK ddPTM_HeLa_Curcumin_4h_R1 1 VDINAPDVDVQGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 78.78 0.0054629 34032000 3708 2283.6 2399.9 2470.5 1822.5 3346.1 2167.2 1895.4 3356.9 3652.6 FALSE FALSE TRUE 3414.507887 2480.984208 2488.842405 2460.277726 1800.767878 2652.081142 2228.005799 2473.298735 2988.656469 3779.527578 0.903421874 0.656427069 0.658506216 0.650948478 0.476453165 0.701696465 0.589493198 0.65439362 0.790748687 1 11.8839902 -7.29904687 1.582423366 0.96711325 0.613513928 0.679423853 0.081899996 0.08413249 0.401144233 0.011415362 0.013345512 5.02E-08 7.29904687 -0.353599322 VDINAPDVDVR ddPTM_HeLa_Curcumin_4h_R1 2 VDINAPDVDVR 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 115.57 0.0068241 2211800 2762.5 2735.9 2517.4 2472.4 2528.4 2978 2380.6 2417 3051 2352.5 FALSE FALSE TRUE 2543.84521 2972.379005 2610.697059 2462.169864 2498.250481 2360.329231 2447.393229 3153.932174 2716.312933 2434.2492 1.04502251 1.221066029 1.072485536 1.011469928 1.026292001 0.96963336 1.005399623 1.295648849 1.11587299 1 11.24926115 -13.52287782 0.01196641 1.43E-07 1.933695452 0 0.102547592 15020.93539 14.52803425 1389.413771 990.1547201 3.00E-14 13.52287782 1.933695309 VDINAPDVGVQGPDWHLK ddPTM_HeLa_Curcumin_4h_R1 1 VDINAPDVGVQGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 87.323 0.0030414 12170000 1367.8 1585.3 1221.5 979.87 1042.3 1812.6 1066.5 1328.9 1208.8 1039.3 FALSE FALSE TRUE 1259.537187 1722.326268 1266.769865 975.8155576 1029.871253 1436.646328 1096.42312 1734.075492 1076.197664 1075.415598 1.171209707 1.601544809 1.177935179 0.907384605 0.957649541 1.335898727 1.019534329 1.612470096 1.000727223 1 10.07067859 -8.6402093 1.098760827 1.020692657 1.206060282 0.12365293 0.229904077 0.792634893 1.927803203 0.080798797 0.044357079 2.29E-09 8.6402093 0.185367624 PVEGDMRHQSIY(ph)VRCTLVPSRK ddPTM_HeLa_Curcumin_4h_R1 1 PVEGDMRHQSIYVRCTLVPSRK 22 3 F5H1X6 F5H1X6 MAP3K4 1 0 PVEGDMRHQS(0.039)IY(0.953)VRCT(0.007)LVPS(0.001)RK 43.12 0.0086613 0 875.34 726.56 678.22 735.59 1027.5 1072.2 1003.1 1064.3 899.88 654.59 TRUE FALSE FALSE 806.0559153 789.3606089 703.3554298 732.5463235 1015.247734 849.8136338 1031.244286 1388.800171 801.1654154 677.3369538 1.190036821 1.165388371 1.038412899 1.081509461 1.498881359 1.254639407 1.52249819 2.050382993 1.182816633 1 9.403729897 -1 0.506915871 1.085840687 32.56534619 0.853695533 0.115021679 25.1411519 0.237103033 0.022929952 850.6880251 0.1 1 31.4795055 up VDINTPDVDVHGPDWHLK ddPTM_HeLa_Curcumin_4h_R1 2 VDINTPDVDVHGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 119.51 0.00011008 66872000 5440.1 4421.5 4679.8 5507 5119.8 5805.2 4525.5 3813.7 5856.8 5067 FALSE FALSE TRUE 5009.510345 4803.674758 4853.237505 5484.213493 5058.749729 4601.136082 4652.47335 4976.479574 5214.323693 5243.077873 0.955452211 0.91619367 0.925646657 1.045991234 0.964843524 0.877563941 0.887355378 0.949152329 0.994515782 1 12.35619826 -5.133294038 0.01133999 1.862737571 2.96E-06 0.246626589 0.043247334 3162.525797 7.771572567 601.6757848 676.1958194 7.36E-06 5.133294038 -1.862734609 VDISAPDVDVHGPDWHLK ddPTM_HeLa_Curcumin_4h_R1 2 VDISAPDVDVHGPDWHLK 18 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 148.7 3.80E-05 84652000 10371.8 8737.5 9377.2 8952.8 9007.6 11654.1 8889.8 8629.3 10301.8 8934.9 FALSE FALSE TRUE 9550.861086 9492.730566 9724.727281 8915.755686 8900.190253 9236.908291 9139.223862 11260.33385 9171.718314 9245.38711 1.033040691 1.026753175 1.051846414 0.96434639 0.962662801 0.999082914 0.988517166 1.217940765 0.992031832 1 13.17451801 -4.257874245 24.80511501 1.009650844 1.217940853 0.840846349 0.028004097 96.84902463 673812.6182 0.0041563 0.040417538 5.52E-05 4.257874245 0.208290009 VDKETNTETPAPS(ph)PTVVRPK ddPTM_HeLa_Curcumin_4h_R1 1 VDKETNTETPAPSPTVVRPK 20 2 H0YBE8;H3BLZ3;Q8IX03;Q8IX03-2;H0YAU4 H0YBE8 WWC1 Protein KIBRA 1 0 VDKETNTETPAPS(0.863)PT(0.137)VVRPK 58.015 0.0057683 4948200 912.08 849.15 881.26 813.09 985.47 1132.9 753.38 601.53 1177.8 950 TRUE FALSE FALSE 839.8879056 922.5467423 913.9202708 809.725649 973.7189139 897.9237696 774.5178152 784.9337279 1048.598287 983.0124293 0.854402122 0.938489397 0.929713851 0.823718627 0.990545882 0.913440912 0.787902362 0.798498274 1.066719255 1 9.941065848 -13.52287875 0.230730733 1.677935357 0.860979605 0.477862063 0.063913819 41.26449017 0.532144683 12.72218399 0.046044828 3.00E-14 13.52287875 -0.816955753 VDLEPVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 VDLEPVSPR 9 0 H7C1V4;Q9HCH0-2;Q9HCH0 H7C1V4 NCKAP5L Nck-associated protein 5-like 1 0 VDLEPVS(1)PR 98.04 0.014279 6309600 2735.3 2499.1 2419.1 2425.9 2317 2520.7 1685.8 1026.1 2650 2014.7 TRUE FALSE FALSE 2518.798119 2715.111068 2508.753974 2415.862269 2289.371288 1997.878406 1733.099011 1338.953166 2359.30163 2084.710675 1.208224311 1.30239227 1.203406307 1.158847747 1.09817219 0.958348048 0.831337908 0.642272898 1.131716577 1 11.02563146 -4.674267873 1.301230931 1.130452311 0.600735229 0.827580821 0.078560487 0.312569474 0.730317132 0.016299945 0.17959703 2.12E-05 4.674267873 -0.529717082 VDLEVARMQAQVT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 VDLEVARMQAQVTK 14 1 B7ZBA8;A0A590PWR5;A6NI56 B7ZBA8 CCDC154 Coiled-coil domain-containing protein 154 1 0 VDLEVARMQAQVT(1)K 94.616 0.011562 5817600 2926 2862.5 3231 2957.2 3269.4 3030.8 2933.9 2975 2911.7 2533.6 TRUE FALSE FALSE 2694.404012 3109.921745 3350.743702 2944.96389 3230.41454 2402.177916 3016.217338 3882.063805 2592.293795 2621.642411 1.027754205 1.186249403 1.278108596 1.123327833 1.232210208 0.916287403 1.150506768 1.480775482 0.988805256 1 11.3562552 -1 0.135666488 0.937545322 2.093827434 0.306907633 0.131978394 73.41964137 0.664077505 0.40675027 16.42856535 0.1 1 1.156282113 RNS(ph)SEASSGDFLDLK ddPTM_HeLa_Curcumin_4h_R1 5 RNSSEASSGDFLDLK 15 1 Q9UK76;J3KT51;Q9UK76-2;Q9UK76-3;J3KSH8 Q9UK76;Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 1 0 RNS(0.887)S(0.113)EASSGDFLDLK;RNS(0.996)S(0.003)EASSGDFLDLK;RNS(0.784)S(0.064)EAS(0.151)S(0.002)GDFLDLK;RNS(0.959)S(0.041)EASSGDFLDLK;RNS(0.861)S(0.132)EAS(0.001)S(0.007)GDFLDLK ;;;; 207.05 2.02E-09 2329365000 19207.59 19345.15 19464.44 19436.69 23876.4 25903.1 27602.7 32472.3 16799.03 17067.24 TRUE FALSE FALSE 17687.28898 21017.25857 20185.80927 19356.26613 23591.68952 20530.50507 28377.15747 42372.95479 14956.21844 17660.32532 1.001526793 1.190083319 1.143003252 1.096031119 1.335858151 1.162521341 1.606830959 2.399330364 0.846882386 1 14.1082243 -1 0.652647546 1.02734831 125.744829 0.930961632 0.110881272 30.73847136 0.182167352 0.01665225 5553.671585 0.1 1 124.7174807 up VDLYQQAS(ph)PPDALR ddPTM_HeLa_Curcumin_4h_R1 1 VDLYQQASPPDALR 14 0 P48634;P48634-2;P48634-3;P48634-4 P48634 PRRC2A Protein PRRC2A 1 0 VDLYQQAS(1)PPDALR 130.47 0.0010766 12246000 2741.9 2170.7 2583.6 2389.4 2370.2 2677.1 2017.4 1454.2 2762.6 2127.6 TRUE FALSE FALSE 2524.875722 2358.325636 2679.350489 2379.513296 2341.936913 2121.839283 2074.002814 1897.578886 2459.549692 2201.533942 1.146871131 1.071219294 1.217038011 1.080843339 1.063775066 0.963800395 0.942071696 0.861934876 1.11719817 1 11.10429337 -4.99366921 1.53352107 1.084209715 0.881536008 0.680049322 0.056625174 0.271717444 1.141727811 0.010601495 0.05433274 1.01E-05 4.99366921 -0.202673707 VDNDENEHQLS(ph)LR ddPTM_HeLa_Curcumin_4h_R1 2 VDNDENEHQLSLR 13 0 P06748;P06748-3;P06748-2;E5RGW4 P06748 NPM1 Nucleophosmin 1 0 VDNDENEHQLS(1)LR;VDNDENEHQLS(1)LR ; 83.792 0.0087136 10523500 5552.8 4539.4 5123 5530.1 5688.2 6083.1 4714.1 3775.7 5705.2 4435.3 TRUE FALSE FALSE 5113.290021 4931.765509 5312.862887 5507.217911 5620.37193 4821.396489 4846.364959 4926.893549 5079.353834 4589.426345 1.114145786 1.074593018 1.157631148 1.199979583 1.224634956 1.050544475 1.055984908 1.073531457 1.106751357 1 12.16409812 -8.974475069 0.673563487 0.9949321 1.122500881 0.05146298 0.064963343 0.723418296 0.574642379 0.050857849 0.013822043 1.06E-09 8.974475069 0.127568781 VDNDENEHQLSLR ddPTM_HeLa_Curcumin_4h_R1 8 VDNDENEHQLSLR 13 0 P06748;P06748-3;P06748-2;E5RGW4 P06748 NPM1 Nucleophosmin 0 0 ;;;;;;; ;;;;;;; 253.97 3.95E-36 1240968900 34530 30795.3 32493.6 30982.7 37150.4 46142.9 33963.3 32073.9 33727.7 28834.7 FALSE FALSE TRUE 31796.91406 33457.10851 33697.8414 30854.5018 36707.40574 36572.3424 34916.21879 41853.08446 30027.85569 29836.70368 1.065697954 1.121340644 1.129408991 1.034112284 1.230276848 1.225750096 1.170243844 1.402738215 1.006406606 1 14.86480054 -1 0.223734176 1.000099501 2.880177215 0.78308475 0.05512105 15.21564514 0.183211192 0.037025231 10.48669994 0.1 1 1.880077715 VDNLTYRTSPDS(ph)LR ddPTM_HeLa_Curcumin_4h_R1 1 VDNLTYRTSPDSLR 14 1 Q9BRL6-2;Q9BRL6 Q9BRL6-2 SRSF8 Serine/arginine-rich splicing factor 8 1 0 VDNLTYRT(0.001)S(0.008)PDS(0.991)LR 72.815 0.012617 7669900 1353.1 1142.6 1008.3 1650.3 1173.4 1675.4 1391.1 1065.3 1754.6 1369.2 TRUE FALSE FALSE 1246.000707 1241.361253 1045.668485 1643.471496 1159.407971 1327.903154 1430.130522 1390.105066 1562.12477 1416.779598 0.879459804 0.876185156 0.738060095 1.160005055 0.818340392 0.937268687 1.00942343 0.981172419 1.102588414 1 10.46839963 -6.265069151 24.9992452 0.921572674 0.971314575 0.061709285 0.117533708 867.217393 5972765.888 0.016236457 0.025396998 5.43E-07 6.265069151 0.049741902 VDPSLMEDS(ph)DDGPSLPTK ddPTM_HeLa_Curcumin_4h_R1 1 VDPSLMEDSDDGPSLPTK 18 0 Q5T092;A0A0A0MR06;Q5T091;O15258 Q5T092 RER1 Protein RER1 1 0 VDPS(0.036)LMEDS(0.963)DDGPS(0.001)LPTK 79.514 0.0082792 0 1761.3 1525.4 1558.2 1427.9 1573.4 1434.6 937.74 909.28 1544.7 1469 TRUE FALSE FALSE 1621.891246 1657.248779 1615.948263 1421.991728 1554.638233 1137.047789 964.0504606 1186.515286 1375.250275 1520.047641 1.067000272 1.090261078 1.063090537 0.935491553 1.022756255 0.74803431 0.634223846 0.780577697 0.904741561 1 10.56990083 -5.232929891 3.768765323 1.032368368 0.703138625 0.802524767 0.065758009 0.053569388 1.663991041 0.007659469 0.02012783 5.85E-06 5.232929891 -0.329229743 VDQSAVGFEYQGK ddPTM_HeLa_Curcumin_4h_R1 2 VDQSAVGFEYQGK 13 0 Q14247;Q14247-3;Q14247-2 Q14247 CTTN Src substrate cortactin 0 0 ; ; 211.67 2.91E-20 3212600 1294.67 1153.68 1158.83 1401.72 1328.47 1522.77 1187.54 1164.04 1468.65 1490.77 FALSE FALSE TRUE 1192.195503 1253.398959 1201.777259 1395.920054 1312.628863 1206.930337 1220.859176 1518.950437 1307.542769 1542.574147 0.772861069 0.812537252 0.779072605 0.904928983 0.850934048 0.782413176 0.791442784 0.984685528 0.847636901 1 10.59112412 -9.401284835 1.104959981 1.000846031 0.827203505 0.045111852 0.07815946 0.326928223 0.708467285 0.044012252 0.010986621 3.97E-10 9.401284835 -0.173642526 VDS(ph)EGDFS(ph)ENDDAAGDFR ddPTM_HeLa_Curcumin_4h_R1 2 VDSEGDFSENDDAAGDFR 18 0 O43823;M0QYL4 O43823 AKAP8 A-kinase anchor protein 8 2 0 VDS(1)EGDFS(1)ENDDAAGDFR;VDS(1)EGDFS(1)ENDDAAGDFR ; 134.08 0.00053468 47104000 4179.6 3081.8 3531.8 4155.7 4092.8 4825 4535.6 3448 4307.8 3902.4 TRUE FALSE FALSE 3848.78025 3348.17706 3662.691615 4138.504815 4043.996033 3824.240611 4662.856729 4499.279327 3835.245118 4038.00811 0.953138316 0.829165512 0.907054051 1.024887693 1.00148289 0.947061152 1.154741794 1.114232365 0.949786383 1 11.97942809 -4.761885096 24.99995115 0.965143454 1.134487125 0.638325021 0.054310902 5.923118029 332330.2859 0.008245582 0.027205647 1.73E-05 4.761885096 0.169343671 VDS(ph)PSHGLVTSSLCIPSPAR ddPTM_HeLa_Curcumin_4h_R1 1 VDSPSHGLVTSSLCIPSPAR 20 0 Q9UER7-3;Q9UER7 Q9UER7-3 DAXX Death domain-associated protein 6 1 0 VDS(0.5)PS(0.5)HGLVTSSLCIPSPAR 91.926 0.0010261 23431000 478.1 419.85 385.67 537.97 641.41 703.74 622.98 326.82 809.06 499.19 TRUE FALSE FALSE 440.2578805 456.1399632 399.9632695 535.7440227 633.7616047 557.7763912 640.4591421 426.4659135 720.3081422 516.5368153 0.852326238 0.88307348 0.774317062 1.037184585 1.226943726 1.079838599 1.23990996 0.825625398 1.394495263 1 9.012727368 -6.010304689 24.61708956 0.913230843 1.10630188 0.011794969 0.193635062 333.9247196 797723.3793 0.017717501 0.030744562 9.77E-07 6.010304689 0.193071036 VDS(ph)PTVTTTLK ddPTM_HeLa_Curcumin_4h_R1 1 VDSPTVTTTLK 11 0 Q07866-6;Q07866-4;G3V5R9;Q07866-7;H0YG16;Q07866-9;G3V3H3;H0YJT3;F8W6L3;E7EVH7;G5E9S8;H0YJU9;H0YJL0;G3V2E7;Q07866-8;Q07866-2;Q07866-3;Q07866-5;Q07866-10;Q07866 Q07866-6 KLC1 Kinesin light chain 1 1 0 VDS(0.887)PT(0.102)VT(0.011)TTLK 112.84 0.0056649 21985000 3374 3333.1 3619.3 3901.1 4528.8 4845.7 4057.1 2038.6 3644.8 2917.4 TRUE FALSE FALSE 3106.94434 3621.198312 3753.434442 3884.958282 4474.797018 3840.647198 4170.931307 2660.159755 3244.974559 3018.779433 1.029205482 1.199557103 1.243361605 1.286930154 1.482319963 1.272251678 1.381661496 0.88120375 1.074929332 1 11.55974963 -7.138547009 1.982541087 1.010302005 1.27749947 0.308897355 0.146747248 0.227954652 1.720295021 0.024678765 0.030647702 7.27E-08 7.138547009 0.267197465 VDS(ph)TTCLFPVEEK ddPTM_HeLa_Curcumin_4h_R1 1 VDSTTCLFPVEEK 13 0 A0A6I8PRN4;A0A6I8PTT9;Q06210-2;Q06210 A0A6I8PRN4 GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 1 0 VDS(0.872)T(0.127)T(0.002)CLFPVEEK 212.55 2.93E-10 5877100 2157.2 1776.4 1830.9 1885.3 2050 3514 2935.4 2052.1 2375.8 2330.8 TRUE FALSE FALSE 1986.455344 1929.944101 1898.754765 1877.499128 2025.555089 2785.156789 3017.759424 2677.775843 2115.180684 2411.795127 0.823641827 0.800210631 0.787278631 0.778465429 0.839853712 1.154806542 1.25125032 1.110283296 0.877015075 1 11.23589165 -5.227819789 6.723726676 0.880917307 1.182110184 0.796017401 0.074494883 0.099967981 14.90157664 0.01421234 0.036036003 5.92E-06 5.227819789 0.301192877 VDSLLENLEK ddPTM_HeLa_Curcumin_4h_R1 1 VDSLLENLEK 10 0 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V2D6;G3V5V7;G3V576;B7ZW38;A0A0G2JPF8;P0DMR1;A0A0G2JNQ3;O60812;B2RXH8 P07910;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL1;HNRNPCL2 Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoprotein C-like 1;Heterogeneous nuclear ribonucleoprotein C-like 2 0 0 117.52 3.95E-07 0 145.07 0 114.44 135.64 72.438 0 0 57.153 0 0 FALSE FALSE TRUE 133.5875564 0 118.6812471 135.0787576 71.57422416 0 0 74.5786866 0 0 0 VDSLVS(ph)LSEEDLESDQR ddPTM_HeLa_Curcumin_4h_R1 2 VDSLVSLSEEDLESDQR 17 0 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2;A0A087WY36;H0YLH1;H0YMW2 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 VDS(0.001)LVS(0.669)LS(0.329)EEDLESDQR;VDSLVS(0.909)LS(0.091)EEDLESDQR ; 239.7 2.41E-30 12196300 3182.8 2905.5 3369.3 3062.22 3152.02 4476.8 2810.12 3565.8 3020.75 2336.75 TRUE FALSE FALSE 2930.878022 3156.638473 3494.169222 3049.549345 3114.43422 3548.261216 2888.964404 4652.996005 2689.381283 2417.951889 1.212132481 1.305500944 1.445094602 1.261211755 1.288046398 1.467465599 1.194798134 1.924354255 1.112255912 1 11.23956982 -1 0.102726066 0.80027463 3.11218248 0.522237127 0.166490189 61.83561186 0.450858765 1.14024783 20.2652404 0.1 1 2.31190785 VDSLVSLS(ph)EEDLESDQR ddPTM_HeLa_Curcumin_4h_R1 2 VDSLVSLSEEDLESDQR 17 0 A0A087WTD7;A8MYJ1;Q12802-4;Q12802;Q12802-2;A0A087WY36;H0YLH1;H0YMW2 A0A087WTD7 AKAP13 A-kinase anchor protein 13 1 0 VDSLVS(0.067)LS(0.933)EEDLESDQR;VDSLVS(0.002)LS(0.998)EEDLESDQR ; 181.81 6.57E-06 23936000 2243.98 2158.14 2184.67 1915 2379.1 2755.25 1739.93 1052.11 2084.58 1919.32 TRUE FALSE FALSE 2066.366615 2344.680005 2265.635792 1907.076237 2350.730786 2183.780092 1788.747753 1372.893496 1855.906789 1986.016227 1.040458072 1.180594586 1.140794199 0.960252092 1.183641279 1.099578172 0.900671268 0.6912801 0.934487223 1 10.9556617 -4.432689753 2.830726208 1.051247036 0.682201636 0.658116076 0.084129808 0.147090463 1.933003315 0.011491557 0.101629371 3.69E-05 4.432689753 -0.369045399 GAGGS(ph)PVGVEEGLVNVGTGQK ddPTM_HeLa_Curcumin_4h_R1 2 GAGGSPVGVEEGLVNVGTGQK 21 0 A0A1W2PQJ7;Q7Z5J4-3;Q7Z5J4-2;Q7Z5J4 A0A1W2PQJ7 RAI1 Retinoic acid-induced protein 1 1 0 GAGGS(1)PVGVEEGLVNVGTGQK;GAGGS(1)PVGVEEGLVNVGTGQK ; 240.82 1.24E-37 28831600 7804.1 6908.6 7078.5 7601.8 6697.9 7319.4 6058.4 2413.63 7429.1 6296.9 TRUE FALSE FALSE 7186.39725 7505.7486 7340.835437 7570.345766 6618.031917 5801.273933 6228.382399 3149.534676 6614.146317 6515.716806 1.102932719 1.151945185 1.126635128 1.161859238 1.015702817 0.89035084 0.955901336 0.48337501 1.015106475 1 12.66970819 -4.014728517 1.16879837 1.067357802 2.35E-16 0.847083707 0.073817044 0.786200373 0.602962424 0.011946875 1.168873573 9.67E-05 4.014728517 -1.067357802 down DPSAS(ph)PGDAGEQAIR ddPTM_HeLa_Curcumin_4h_R1 1 DPSASPGDAGEQAIR 15 0 P18206;P18206-2 P18206 VCL Vinculin 1 0 DPS(0.386)AS(0.614)PGDAGEQAIR 209.23 8.07E-10 33803000 1005.8 662.93 1178.8 596.56 1668 1587.7 1546.3 1751.2 606.98 580.49 TRUE FALSE FALSE 926.1898687 720.2307152 1222.487365 594.0915928 1648.110189 1258.393123 1589.685016 2285.132818 540.3958126 600.6619843 1.541948538 1.199061592 2.035233454 0.989061416 2.743823036 2.095010432 2.646555064 3.804357323 0.899667079 1 9.230409549 -1 0.312902716 1.15306021 24.66608735 0.787313234 0.417923049 15.13825442 0.193383101 0.132362728 204.9550414 0.1 1 23.51302714 up VDTNAPDLSLEGPEGK ddPTM_HeLa_Curcumin_4h_R1 1 VDTNAPDLSLEGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 206.06 2.38E-18 1109300 612.28 427.25 417.83 780.1 535.07 536.18 670.84 577.4 721.35 449.5 FALSE FALSE TRUE 563.8173919 464.1795862 433.3151474 776.8721529 528.6896397 424.970224 689.6619649 753.446602 642.2197097 465.1200915 1.212197456 0.99797793 0.931619931 1.670261438 1.136673408 0.913678492 1.482761071 1.619896916 1.380761058 1 8.86145945 -1 0.635474827 1.104672432 45.30475591 0.252361859 0.234753036 156.2102453 0.985205957 0.037530053 9702.588245 0.1 1 44.20008348 VDVADQAQDKDRDDR ddPTM_HeLa_Curcumin_4h_R1 2 VDVADQAQDKDRDDR 15 2 E7EX17;P23588-2;P23588;F8VP89;F8W0K0;F8VSC7 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 0 ; ; 63.727 0.015276 106823500 10218.8 9554.4 10182.3 10356.6 11482.1 12560.8 9633.5 10635.7 10490.6 9211.1 FALSE FALSE TRUE 9409.971197 10380.23976 10559.665 10313.74713 11345.18346 9955.548491 9903.790083 13878.47597 9339.807426 9531.185039 0.987282395 1.089081758 1.107906829 1.082105435 1.190322443 1.044523682 1.039093255 1.456112321 0.9799209 1 13.21843988 -2.095555658 1.398924193 1.028515071 199.9851971 0.734547962 0.068995614 271.9357724 1.468166875 0.011506296 172672.0199 0.008024987 2.095555658 198.956682 VDVDVPDVNIEGPDAK ddPTM_HeLa_Curcumin_4h_R1 2 VDVDVPDVNIEGPDAK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 206.49 1.54E-09 17401700 8001 6515 7215.7 7450.7 7973.6 8364.3 7757.3 6840.4 7610.6 6490.6 FALSE FALSE TRUE 7367.712407 7078.12757 7483.12019 7419.870978 7878.520028 6629.449895 7974.94896 8926.006471 6775.736221 6716.147867 1.097014621 1.053896923 1.114198248 1.104780765 1.173071258 0.987091116 1.187429032 1.329036622 1.008872401 1 12.71341828 -1 0.730815364 1.056904339 43.88601938 0.641295911 0.059454814 154.5040855 0.677149876 0.010273365 10877.86079 0.1 1 42.82911504 GFEGS(ph)CSQKESEEGNPVR ddPTM_HeLa_Curcumin_4h_R1 1 GFEGSCSQKESEEGNPVR 18 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 GFEGS(0.559)CS(0.44)QKESEEGNPVR 84.41 0.0021179 20027000 1291.5 1041.5 1322.2 1350 1601.6 2129.2 2262.3 2845.9 1439.4 1190.2 TRUE FALSE FALSE 1189.276412 1131.522619 1371.201895 1344.414058 1582.501966 1687.579919 2325.774049 3713.601809 1281.501421 1231.559361 0.965667145 0.918772294 1.113386766 1.091635612 1.284957929 1.370278991 1.888479047 3.015365662 1.04055189 1 10.26627045 -1 0.637992742 0.982379328 170.8982579 0.99043995 0.059788213 11.11218166 0.069453996 0.009931705 2665.357138 0.1 1 169.9158786 up VDVGKDQEFTVK ddPTM_HeLa_Curcumin_4h_R1 2 VDVGKDQEFTVK 12 1 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 116.24 0.00065064 47716000 21770.9 17202.6 17784.7 18954.3 19173 22770.5 18521.5 17804.6 22384.7 19247.9 FALSE FALSE TRUE 20047.71029 18689.51609 18443.81663 18875.87213 18944.3745 18047.64162 19041.16344 23233.14058 19929.15441 19916.76309 1.006574723 0.938381202 0.926044887 0.947737945 0.951177378 0.906153351 0.95603705 1.166511871 1.000622155 1 14.28169558 -7.285329428 23.28013514 1.003104735 0.963972371 0.038553616 0.068539603 703.4464048 685484.7269 0.011297621 0.012924928 5.18E-08 7.285329428 -0.039132364 VDVGKDQEFTVK(ac)SK ddPTM_HeLa_Curcumin_4h_R1 1 VDVGKDQEFTVKSK 14 2 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 1 VDVGKDQEFTVK(1)SK 93.228 0.0031591 2895900 767.52 870.25 841.16 752.54 754.38 1003.5 878.45 755.49 1086.1 801.52 FALSE TRUE FALSE 706.7699821 945.4705322 872.3341296 749.4261889 745.3845112 795.3627882 903.0969428 985.8354232 966.9575473 829.3727603 0.852174096 1.13998262 1.051799831 0.903605984 0.89873281 0.958993141 1.088891492 1.188651798 1.165890168 1 9.695876854 -4.585120329 2.57341447 0.94936839 1.18436399 0.149799055 0.105205679 0.227294105 2.729886227 0.013038072 0.084517968 2.60E-05 4.585120329 0.2349956 VDVNAPDVQAPDWHLK ddPTM_HeLa_Curcumin_4h_R1 1 VDVNAPDVQAPDWHLK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 98.062 0.0027234 21580000 1211.9 1019 885.97 1048.4 993.48 1233.7 931.88 1012.1 1207.2 969.59 FALSE FALSE TRUE 1115.976836 1107.077819 918.8048276 1044.061999 981.6333999 977.8167133 958.0260448 1320.684631 1074.77318 1003.28318 1.112324873 1.103454978 0.915798097 1.040645372 0.978421067 0.97461687 0.954890966 1.316362774 1.071256053 1 9.970513154 -4.251595705 24.67056277 1.032304436 1.31636296 0.663309795 0.063161618 617.4759841 1547502.386 0.009870094 0.172540571 5.60E-05 4.251595705 0.284058524 VDVS(ph)CEPLEGVEK ddPTM_HeLa_Curcumin_4h_R1 1 VDVSCEPLEGVEK 13 0 A6NNK5;Q12888;Q12888-3;Q12888-2;C9JXV0;H7C3N7 A6NNK5 TP53BP1 Tumor suppressor p53-binding protein 1 1 0 VDVS(1)CEPLEGVEK 158.81 0.00030145 62675000 8050.8 6652.6 7035 7930.8 8257.8 11384 7538.7 5660.7 7875 6026 TRUE FALSE FALSE 7413.570685 7227.621101 7295.723289 7897.984451 8159.331128 9022.830076 7750.215633 7386.621371 7011.132202 6235.403051 1.188948112 1.15912653 1.170048388 1.266635755 1.308549112 1.447032373 1.242937396 1.184626128 1.124407219 1 12.6062671 -8.36006139 0.302940856 0.942369113 1.314916948 0.49577621 0.079985015 1.00173125 0.2114822 0.143485 0.05842984 4.36E-09 8.36006139 0.372547835 VEADVSLPS(ph)MQGDLK ddPTM_HeLa_Curcumin_4h_R1 1 VEADVSLPSMQGDLK 15 0 Q8IVF2;Q8IVF2-3 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 VEADVS(0.217)LPS(0.783)MQGDLK 123.76 0.0012133 5661500 2037.4 1301 1882.3 1588.5 1622.2 2447.9 1430.9 1683.5 1732 1235.9 TRUE FALSE FALSE 1876.13764 1413.452643 1952.059694 1581.927208 1602.856324 1940.177946 1471.047203 2196.7914 1542.003933 1278.847433 1.467053529 1.105255096 1.526421091 1.236994474 1.253360083 1.51713011 1.150291399 1.717790053 1.205776306 1 10.32062845 -9.421572495 0.938521559 0.980057674 1.367021026 0.213623146 0.190809219 0.51442652 0.740148559 0.145728029 0.029902778 3.79E-10 9.421572495 0.386963352 VEAIVIS(ph)DEETDVSDEQPQGPER ddPTM_HeLa_Curcumin_4h_R1 1 VEAIVISDEETDVSDEQPQGPER 23 0 A0A6E1W9L1;Q9H5J0 A0A6E1W9L1 ZBTB3 Zinc finger and BTB domain-containing protein 3 1 0 VEAIVIS(0.996)DEET(0.004)DVSDEQPQGPER 103.73 1.29E-05 3744800 1748.9 1469.9 1497.2 1739.6 1441 2229.4 1100.7 972.33 1551.5 1760.2 TRUE FALSE FALSE 1610.47272 1596.951606 1552.687549 1732.401996 1423.817016 1766.997309 1131.58268 1268.788941 1381.304332 1821.366819 0.884211079 0.876787471 0.852484811 0.951154912 0.781729963 0.970149061 0.621282143 0.696613624 0.758388874 1 10.83080579 -2.393138146 0.244199354 0.973089936 1.06E-25 0.229052849 0.102698588 13.67126079 0.306866044 0.048326734 4.754417588 0.004044472 2.393138146 -0.973089936 VEAK(ac)FINYVK ddPTM_HeLa_Curcumin_4h_R1 2 VEAKFINYVK 10 1 P06748;P06748-2 P06748 NPM1 Nucleophosmin 0 1 ; VEAK(1)FINYVK;VEAK(1)FINYVK 117.02 0.0033332 51754000 9003.1 6344.7 7751.9 7147.6 6750.2 13093.8 10598.4 13039.7 8253.6 8471.3 FALSE TRUE FALSE 8290.495135 6893.107597 8039.192233 7118.025125 6669.708274 10377.99828 10895.76258 17015.4445 7348.200729 8765.677044 0.945790621 0.786374807 0.917121654 0.812033696 0.760889118 1.183935734 1.243002968 1.941144354 0.838292432 1 13.09764981 -4.103824303 1.31336133 0.933605759 2.664090833 0.898030309 0.107550375 0.447726273 0.508839058 0.016418341 1.137218535 7.87E-05 4.103824303 1.730485074 VEAKEESEES(ph)DEDMGFGLFD ddPTM_HeLa_Curcumin_4h_R1 1 VEAKEESEESDEDMGFGLFD 20 1 F8VWS0;P05388-2;Q8NHW5;P05388;F8W1K8 F8VWS0 RPLP0;RPLP0P6 60S acidic ribosomal protein P0;60S acidic ribosomal protein P0-like 1 0 VEAKEES(0.002)EES(0.998)DEDMGFGLFD 79.92 0.00634 38681000 5115.6 4261.3 4477.7 4699.3 4481.7 6291.3 4287.9 4863.8 5196.5 4379.9 TRUE FALSE FALSE 4710.694862 4629.627784 4643.647501 4679.855542 4428.258655 4986.413462 4408.206934 6346.75023 4626.456951 4532.101199 1.039406371 1.021519066 1.024612491 1.032601731 0.977087329 1.100243186 0.972662953 1.400399054 1.020819427 1 12.14596436 -4.257002938 24.99712446 1.020859311 1.400399205 0.918651278 0.033870629 79.91247177 450250.0105 0.004240261 0.044994766 5.53E-05 4.257002938 0.379539894 VEAKPEVQSQPPR ddPTM_HeLa_Curcumin_4h_R1 1 VEAKPEVQSQPPR 13 1 Q9UN86-2;Q9UN86 Q9UN86-2 G3BP2 Ras GTPase-activating protein-binding protein 2 0 0 87.216 0.01179 3280300 1587.2 1089.1 1366.2 1547.2 1319.2 1679.5 1125.7 1432.2 1543.9 1620.2 FALSE FALSE TRUE 1461.571445 1183.236951 1416.832574 1540.798096 1303.469402 1331.152768 1157.284112 1868.871187 1374.538033 1676.501829 0.8717983 0.70577731 0.845112453 0.919055422 0.777493575 0.794006153 0.690296958 1.114744496 0.819884601 1 10.71123834 -8.51869646 0.850979284 0.988626241 0.829970274 0 0.125752397 0.55544325 0.827558811 0.044442935 0.022925199 3.03E-09 8.51869646 -0.158655967 VEANS(ph)PLPK ddPTM_HeLa_Curcumin_4h_R1 2 VEANSPLPK 9 0 Q9H7C4-2;Q9H7C4 Q9H7C4-2 SYNC Syncoilin 1 0 VEANS(1)PLPK;VEANS(1)PLPK ; 95.477 0.015782 98403000 13233.4 11407.1 11419.8 11702.7 10580.6 12576.2 9671.7 6174 13676.4 12167.1 TRUE FALSE FALSE 12185.96243 12393.07889 11843.02783 11654.27733 10454.43326 9967.754357 9943.061872 8056.424178 12176.13314 12589.90582 0.967915297 0.984366291 0.940676444 0.925684234 0.830382165 0.791725887 0.789764595 0.639911394 0.967134569 1 13.61997987 -3.798969292 0.387567048 0.995976876 0.264749045 0.949436752 0.024865453 1.018265288 0.080536911 0.00642122 0.371864553 0.000158866 3.798969292 -0.73122783 VEAPETNIDKT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 VEAPETNIDKTPK 13 1 O75152;E9PBY7;E9PQ61 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 0 VEAPETNIDKT(1)PK 136.57 0.002992 0 1471.8 1760.4 983.56 1137.1 1313.4 1786 1402.9 674.33 1680.8 1346.6 TRUE FALSE FALSE 1355.305477 1912.561132 1020.011599 1132.394981 1297.738563 1415.563468 1442.261598 879.9301128 1496.420445 1393.39425 0.972664755 1.37259152 0.732033736 0.81268814 0.931350594 1.015910226 1.035070726 0.63150118 1.073939013 1 10.4443878 VEAPEYIPISDDPKAS(ph)AK ddPTM_HeLa_Curcumin_4h_R1 2 VEAPEYIPISDDPKASAK 18 1 Q1ED39;H3BPL4 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 1 0 VEAPEYIPIS(0.022)DDPKAS(0.978)AK;VEAPEYIPIS(0.006)DDPKAS(0.994)AK ; 96.016 0.00086649 47302000 6094.1 4941.5 6071.1 5721.7 6854.7 9746.5 8667.6 3830.6 6116.9 4741.3 TRUE FALSE FALSE 5611.745555 5368.621241 6296.100307 5698.025121 6772.962179 7724.966034 8910.789528 4998.532306 5445.891374 4906.059822 1.14383961 1.094283689 1.283331336 1.161425936 1.38052988 1.574576404 1.816282282 1.018848625 1.110033626 1 12.26034911 -6.06709361 0.941433333 1.06640424 1.502220752 0.374463175 0.197310375 0.362860796 0.629923309 0.033252709 0.083777612 8.57E-07 6.06709361 0.435816512 LDDQES(ph)PVYAAQQR ddPTM_HeLa_Curcumin_4h_R1 1 LDDQESPVYAAQQR 14 0 Q96ST3;H3BMA2;H3BT34;H3BQ76;H3BQ88;H3BNA0;H3BNZ3;H3BQL7;H3BP90 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 0 LDDQES(1)PVYAAQQR 117.13 0.0020285 7197500 2508.4 1944.5 1921.8 2218.8 2645.8 3607.6 3254 3839.2 2418.7 1790.9 TRUE FALSE FALSE 2309.857493 2112.573915 1993.023599 2209.619194 2614.250563 2859.343094 3345.298482 5009.754406 2153.374661 1853.133642 1.246460288 1.140000844 1.075488326 1.192369047 1.410718852 1.542977274 1.805211673 2.703396179 1.162018007 1 10.85575121 -1 0.566153248 1.108345982 81.09985789 0.975219535 0.076019415 16.85394935 0.134015268 0.018099702 1655.811819 0.1 1 79.99151191 up VEAQLQELQVK ddPTM_HeLa_Curcumin_4h_R1 1 VEAQLQELQVK 11 0 P35579 P35579 MYH9 Myosin-9 0 0 180.88 1.14E-11 1685200 627.61 535.78 828.51 662.86 787.49 1030.7 731.26 670.28 787.78 719.37 FALSE FALSE TRUE 577.9340062 582.0904358 859.2153094 660.117261 778.0996961 816.9212016 751.7771875 874.6452864 701.3625049 744.368054 0.776408933 0.781992769 1.154288265 0.886815679 1.045315811 1.097469454 1.009953589 1.175017227 0.942225424 1 9.53987233 -5.940176739 0.976761065 0.891528128 1.094374319 0.34561023 0.107942951 0.510667722 0.949208376 0.021279953 0.058030997 1.15E-06 5.940176739 0.202846192 VEDMAELTCLNEASVLHNLK ddPTM_HeLa_Curcumin_4h_R1 1 VEDMAELTCLNEASVLHNLK 20 0 P35579;Q5BKV1;B1AH99;E7ERA5;P35580;P35580-5;P35580-2;P35580-3;P35580-4 P35579;P35580 MYH9;MYH10 Myosin-9;Myosin-10 0 0 127.22 0.00026793 15614000 1714.9 1427.9 1479.8 1587.8 2029.7 2568.1 1969 1376.9 1875.6 1627.4 FALSE FALSE TRUE 1579.163855 1551.321313 1534.64269 1581.230104 2005.497153 2035.447112 2024.244841 1796.710472 1669.851373 1683.952029 0.937772471 0.921238424 0.911333971 0.938999495 1.190946725 1.208732242 1.202079873 1.066960603 0.99162645 1 10.71763533 -5.761180198 24.99996233 0.958899837 1.172640774 0.842920116 0.04577796 2.115941979 204059.3405 0.00723302 0.013773414 1.73E-06 5.761180198 0.213740937 VEEAEPEEFVVEK ddPTM_HeLa_Curcumin_4h_R1 1 VEEAEPEEFVVEK 13 0 Q13185;S4R2Y4;C9JMM0;B8ZZ43 Q13185 CBX3 Chromobox protein homolog 3 0 0 165.7 0.0015282 5675900 3007 2326.2 2538.4 2619.6 2957.1 3102.9 2245.9 1973.5 2755.9 2521.2 FALSE FALSE TRUE 2768.992777 2527.266363 2632.475337 2608.760789 2921.838514 2459.323563 2308.913909 2575.211065 2453.584665 2608.811512 1.061400091 0.968742414 1.00907073 0.999980557 1.119988355 0.942698831 0.885044358 0.987120401 0.940499018 1 11.349177 -5.033811174 24.80651926 1.026648687 0.930529666 0.28433848 0.052627565 341.1763445 250313.7048 0.006294081 0.016058305 9.25E-06 5.033811174 -0.096119021 VEEAPVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VEEAPVKK 8 1 H0Y9Y2;Q8NFC6 H0Y9Y2;Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 0 1 ; VEEAPVK(1)K;VEEAPVK(1)K 131.06 0.00052564 46012000 17975.2 15635 15087.7 13714 13173.5 17750 12290.8 10565.4 14579 14065.1 FALSE TRUE FALSE 16552.44395 16986.41973 15646.86343 13657.2551 13016.41462 14068.44992 12635.64677 13786.74182 12979.72017 14553.86118 1.137323199 1.1671418 1.0751005 0.938393938 0.894361603 0.966647252 0.868198935 0.947291008 0.891840318 1 13.82911433 -6.233573856 4.822004589 1.07671446 0.91927462 0.411771809 0.076333474 0.110900979 6.85749933 0.009982809 0.016428157 5.84E-07 6.233573856 -0.157439841 QPGVDSLS(ph)PVASLPK ddPTM_HeLa_Curcumin_4h_R1 2 QPGVDSLSPVASLPK 15 0 A0A087X151;Q9UBW7-2;Q9UBW7 A0A087X151 ZMYM2 Zinc finger MYM-type protein 2 1 0 QPGVDS(0.139)LS(0.861)PVASLPK;QPGVDS(0.001)LS(0.995)PVAS(0.005)LPK ; 179.46 6.28E-05 16644600 5465.3 5158.6 5423.7 5699.9 6375.2 8062.9 8678.1 8567 5591.4 4656.6 TRUE FALSE FALSE 5032.715738 5604.486398 5624.707093 5676.315324 6299.179904 6390.563652 8921.58413 11179.03886 4978.037409 4818.416503 1.044475033 1.163138636 1.167335179 1.1780458 1.307313284 1.326278799 1.85155935 2.320064871 1.033127254 1 12.23434339 -1 0.470918602 1.022968098 36.54221664 0.974500952 0.064031128 8.030618426 0.082776799 0.013181233 279.8685405 0.1 1 35.51924855 up VEEASPGRPS(ph)SVDTLLSPTALIDSILR ddPTM_HeLa_Curcumin_4h_R1 2 VEEASPGRPSSVDTLLSPTALIDSILR 27 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 1 0 VEEAS(0.099)PGRPS(0.45)S(0.45)VDT(0.001)LLSPTALIDSILR;VEEAS(0.143)PGRPS(0.416)S(0.416)VDT(0.007)LLS(0.012)PT(0.004)ALIDS(0.002)ILR ; 105.69 4.85E-08 292410000 2256 2162.2 2093.57 2179.8 2735.8 3729.3 2408 1795.76 2401 2313.7 TRUE FALSE FALSE 2077.435219 2349.090933 2171.159546 2170.780565 2703.177372 2955.801142 2475.561999 2343.278957 2137.616307 2394.100903 0.867730853 0.981199636 0.90687888 0.906720583 1.129099182 1.234618448 1.034025757 0.978772012 0.892868093 1 11.22526824 -5.761588516 25 0.935242311 1.09987076 0.562641191 0.072310933 2.574953042 431743.7777 0.011804673 0.022420845 1.73E-06 5.761588516 0.164628448 VEEEEER ddPTM_HeLa_Curcumin_4h_R1 2 VEEEEER 7 0 P35579;P35579-2;P35580;P35580-5;P35580-2;P35580-3;P35580-4 P35579;P35580 MYH9;MYH10 Myosin-9;Myosin-10 0 0 ; ; 126.28 0.0088911 1780430 3129.4 6523.2 2212.6 2286.7 1708.38 2006.02 1424.55 1312.59 1799.2 2294.42 FALSE FALSE TRUE 2881.704688 7087.036341 2294.600902 2277.238241 1688.008684 1589.948839 1464.519039 1712.792649 1601.832261 2374.150924 1.213783277 2.985082485 0.966493275 0.959180066 0.710994683 0.669691561 0.616860126 0.721433769 0.674696897 1 11.21319593 -6.529134613 24.9999722 1.279878998 0.747884835 0.235980763 0.585376211 232.5502557 929324.5157 0.093191938 0.131990341 2.96E-07 6.529134613 -0.531994163 VEEEQEADEEDVS(ph)EEEAESKEGTNKDFPQNAIR ddPTM_HeLa_Curcumin_4h_R1 1 VEEEQEADEEDVSEEEAESKEGTNKDFPQNAIR 33 2 Q9H3N1 Q9H3N1 TMX1 Thioredoxin-related transmembrane protein 1 1 0 VEEEQEADEEDVS(0.63)EEEAES(0.08)KEGT(0.29)NKDFPQNAIR 52.255 0.0014812 49965000 1138.7 977.14 813.52 1795.7 781.33 1467.6 604.93 271.07 1984 1545.6 TRUE FALSE FALSE 1048.570693 1061.599628 843.6697668 1788.269869 772.0131501 1163.203217 621.9027077 353.7179951 1766.360164 1599.309485 0.655639639 0.663786239 0.527521268 1.118151231 0.482716546 0.7273159 0.388857012 0.221169197 1.104451753 1 10.64323343 -6.262938633 0.112276956 1.269072992 2.10E-25 0.500802185 0.204077178 12.10392112 0.584316937 2.364157539 4.055520728 5.46E-07 6.262938633 -1.269072992 VEEESTGDPFGFDS(ph)DDESLPVSSK ddPTM_HeLa_Curcumin_4h_R1 3 VEEESTGDPFGFDSDDESLPVSSK 24 0 Q7Z5K2;Q7Z5K2-2;Q7Z5K2-3 Q7Z5K2 WAPAL Wings apart-like protein homolog 1 0 VEEESTGDPFGFDS(0.989)DDES(0.011)LPVSSK;VEEESTGDPFGFDS(0.766)DDES(0.232)LPVS(0.001)S(0.001)K;VEEEST(0.001)GDPFGFDS(0.931)DDES(0.066)LPVS(0.002)SK ;; 125.52 4.33E-07 75033000 34611.4 27959.1 30253.9 30999.6 31865.7 36981.5 26874.8 17996 34368.6 31459.2 TRUE FALSE FALSE 31871.87117 30375.76002 31375.13615 30871.33187 31485.72234 29311.12003 27628.83456 23482.89756 30598.45057 32552.40486 0.979094212 0.933134131 0.963834662 0.948357948 0.967231837 0.900428714 0.848749414 0.721387488 0.939975117 1 14.99047651 -3.20566867 0.570810345 0.985870564 1.74E-13 0.907736151 0.02359223 1.643388933 0.149882879 0.003765797 1.416242026 0.000622775 3.20566867 -0.985870564 VEEIAASK ddPTM_HeLa_Curcumin_4h_R1 2 VEEIAASK 8 0 M0R0P7;M0R3D6;M0R1A7;M0R117;Q02543 M0R0P7 RPL18A 60S ribosomal protein L18a 0 0 ; ; 133.86 0.0012886 19805600 11113.1 9608.6 9450 9344 8688.1 9795.6 8307 7778.7 10246.2 9083.5 FALSE FALSE TRUE 10233.48641 10439.12457 9800.225313 9305.337004 8584.500082 7763.882141 8540.072063 10150.38982 9122.217495 9399.150949 1.088767109 1.110645485 1.04267134 0.990018892 0.913327185 0.826019518 0.908600374 1.079926248 0.970536333 1 13.19831472 -6.007619591 2.979613001 1.049077264 0.923295027 0.353708917 0.069599073 0.198258924 3.588812255 0.010693845 0.019665238 9.83E-07 6.007619591 -0.125782237 VEEIAASK(ac)CR ddPTM_HeLa_Curcumin_4h_R1 1 VEEIAASKCR 10 1 M0R0P7;M0R3D6;M0R1A7;M0R117;Q02543 M0R0P7 RPL18A 60S ribosomal protein L18a 0 1 VEEIAASK(1)CR 119.22 0.0030059 4827100 1823.3 1962.8 1828 2181.7 1854.5 1815 1355.5 1577.6 2109.6 1737.6 FALSE TRUE FALSE 1678.983881 2132.455686 1895.747288 2172.672703 1832.386299 1438.548541 1393.531682 2058.602978 1878.182158 1797.981471 0.933816009 1.186027621 1.05437532 1.208395492 1.019135252 0.80009086 0.775053417 1.144952276 1.044605959 1 10.81216244 -3.934198123 20.43095313 0.985902437 4.661119708 0.080625975 0.134419976 701.5747468 227973.8884 0.018724121 5402.087939 0.00011636 3.934198123 3.675217271 VEEK(ac)ASR ddPTM_HeLa_Curcumin_4h_R1 1 VEEKASR 7 1 P20962;F5H7R9;F5GXR3 P20962 PTMS Parathymosin 0 1 VEEK(1)ASR 101.43 0.019784 1256400 771.68 753.74 659.66 609.52 664.21 776.56 670.93 652.4 819.03 529.24 FALSE TRUE FALSE 710.6007137 818.889927 684.1075799 606.9979677 656.2897296 615.4927024 689.7544901 851.3137567 729.1844581 547.6310506 1.297590253 1.495331439 1.249212548 1.108406777 1.198415847 1.123918561 1.259524071 1.554538874 1.331525043 1 9.097060439 -9.145343201 0.934560837 1.002281654 1.275064199 0 0.169109677 0.500794505 0.798929759 0.089534103 0.026791398 7.16E-10 9.145343201 0.272782545 VEELEHR ddPTM_HeLa_Curcumin_4h_R1 1 VEELEHR 7 0 Q08379;A0A087WYC0;Q08379-2 Q08379 GOLGA2 Golgin subfamily A member 2 0 0 143.11 0.002611 2634900 3455.7 3112.2 2847.3 2562.2 2984.5 3194 1976.6 1174.9 3621.7 3304.1 FALSE FALSE TRUE 3182.177699 3381.2047 2952.823443 2551.598295 2948.911787 2531.528396 2032.058076 1533.121601 3224.408571 3418.917229 0.930755992 0.988969453 0.863672106 0.746317657 0.862527984 0.740447407 0.594357201 0.448423141 0.943108111 1 11.73932378 -4.039700034 0.411299645 0.980203114 1.57E-15 0.911318302 0.050901809 1.190097193 0.119667167 0.013333412 0.593254289 9.13E-05 4.039700034 -0.980203114 down VEENPDADS(ph)DFDAK ddPTM_HeLa_Curcumin_4h_R1 1 VEENPDADSDFDAK 14 0 Q9H0G5;A0A024QZ33 Q9H0G5 NSRP1;CCDC55 Nuclear speckle splicing regulatory protein 1 1 0 VEENPDADS(1)DFDAK 165.16 0.00021653 56894000 7600.2 7343.5 7442.9 6578.7 8653.2 8945.6 5991.4 6583.3 6641.4 5429.3 TRUE FALSE FALSE 6998.63615 7978.239418 7718.740421 6551.479083 8550.016242 7090.181722 6159.502559 8590.517864 5912.855036 5617.967771 1.245759398 1.420129083 1.373938181 1.166165302 1.521905534 1.262054538 1.09639336 1.529114836 1.052490024 1 12.45583263 -8.556886159 0.691215936 1.006967736 1.328734092 0.445639106 0.13435403 0.438331554 0.426987206 0.069844599 0.030063285 2.77E-09 8.556886159 0.321766356 VEENPDADS(ph)DFDAKS(ph)SADDEIEETR ddPTM_HeLa_Curcumin_4h_R1 1 VEENPDADSDFDAKSSADDEIEETR 25 1 Q9H0G5;A0A024QZ33 Q9H0G5 NSRP1;CCDC55 Nuclear speckle splicing regulatory protein 1 2 0 VEENPDADS(0.973)DFDAKS(0.878)S(0.145)ADDEIEET(0.003)R 50.891 0.014161 17195000 1784.3 1814.2 1671.5 1556.4 1960.4 1909.7 1812.1 1560 1814.5 1414.1 TRUE FALSE FALSE 1643.070772 1971.011364 1733.44726 1549.960029 1937.02351 1513.606693 1862.942649 2035.636819 1615.45389 1463.23987 1.122899127 1.34701863 1.18466377 1.059265853 1.323790822 1.03442144 1.273162854 1.391184631 1.104025337 1 10.51495058 -13.52287874 0.057970165 0.094041407 1.604279797 0.255377679 0.115421156 234.2804903 1.068328369 30.66397621 6.094614023 3.00E-14 13.52287874 1.51023839 VEESSEIS(ph)PEPK ddPTM_HeLa_Curcumin_4h_R1 2 VEESSEISPEPK 12 0 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 0 VEESS(0.005)EIS(0.995)PEPK;VEES(0.005)S(0.003)EIS(0.991)PEPK ; 170.66 0.00013028 36299000 8943 8700.2 9017.2 8575 10774.3 8029.4 4932.3 4726.2 7546.4 7236.4 TRUE FALSE FALSE 8235.152113 9452.206521 9351.385364 8539.518922 10645.82351 6364.01193 5070.687063 6167.196623 6718.5788 7487.864361 1.099799852 1.262336771 1.248872163 1.140447865 1.421743637 0.849910151 0.677187355 0.823625579 0.897262354 1 12.87033859 -5.017881486 24.15124589 1.109998333 0.75369195 0.572960718 0.144502302 260.0209269 351193.8003 0.020390538 0.053265895 9.60E-06 5.017881486 -0.356306383 VEET(ph)SPLGNAR ddPTM_HeLa_Curcumin_4h_R1 2 VEETSPLGNAR 11 0 P30414;A0A087WYW3 P30414 NKTR NK-tumor recognition protein;Putative peptidyl-prolyl cis-trans isomerase 1 0 VEET(0.87)S(0.13)PLGNAR;VEET(0.863)S(0.137)PLGNAR ; 138.42 0.0045918 54202000 9188 7831.2 8513.5 8334.2 10175.8 10079 9475.8 11685.5 8263.4 7857.6 TRUE FALSE FALSE 8460.760105 8508.094033 8829.017799 8299.715289 10054.46023 7988.501786 9741.665445 15248.35516 7356.925694 8130.651015 1.040600573 1.046422238 1.085893095 1.020793449 1.236611953 0.98251687 1.19814089 1.875416265 0.904838454 1 12.98915516 -4.262588726 2.778952938 1.03997405 2.030921722 0.905214989 0.08081386 0.076118429 0.795086434 0.009485655 0.170998313 5.46E-05 4.262588726 0.990947671 VEETVKHDWDR ddPTM_HeLa_Curcumin_4h_R1 4 VEETVKHDWDR 11 1 E2QRB9;E9PIR7;F8W809;A0A087WSW9;A0A182DWI3;A0A087WSY9;Q16881-7;Q16881-5;Q16881-2;Q16881-4;Q16881-3;Q16881-6;Q16881;E9PKD3;A0A0B4J225 E2QRB9 TXNRD1 "Thioredoxin reductase 1, cytoplasmic" 0 0 ;;; ;;; 93.561 0.0069361 267187000 14472.3 11530.6 12493.3 12455.6 11438.1 16284.9 11972 12756.4 16608.1 13782.1 FALSE FALSE TRUE 13326.80218 12527.25368 12956.31269 12404.06203 11301.70813 12907.22817 12307.9021 16645.76764 14786.23298 14261.02695 0.93449106 0.878425777 0.9085119 0.869787433 0.79248908 0.905070036 0.863044586 1.167220825 1.036828065 1 13.79979025 -8.291687986 0.883695693 0.991126815 0.904573597 0.144914947 0.09387266 0.770155425 1.269230782 0.03111462 0.019507883 5.11E-09 8.291687986 -0.086553217 VEFMDDTS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 VEFMDDTSR 9 0 P62857 P62857 RPS28 40S ribosomal protein S28 1 0 VEFMDDT(0.03)S(0.97)R 110.54 0.0089755 5130500 4383.4 3611.7 4137.7 4225 4190.3 4946.9 3800.6 2864.2 4221.9 3759.7 TRUE FALSE FALSE 4036.449265 3923.879255 4291.046802 4207.518069 4140.333409 3920.857177 3907.234607 3737.481395 3758.768133 3890.349295 1.037554461 1.008618753 1.102997823 1.081527069 1.064257499 1.007841939 1.004340307 0.960705868 0.966177545 1 11.92568398 -4.430392186 1.767512125 1.031191325 0.952005848 0.260333059 0.038616214 0.721901571 2.879830506 0.005524597 0.085060974 3.71E-05 4.430392186 -0.079185476 VEFMDDTSR ddPTM_HeLa_Curcumin_4h_R1 2 VEFMDDTSR 9 0 P62857 P62857 RPS28 40S ribosomal protein S28 0 0 ; ; 144.09 1.16E-05 16458100 5711.1 4786.4 5067.9 5114.3 5166.9 6531.1 4797.4 4743.3 5630.6 4934.6 FALSE FALSE TRUE 5259.060409 5200.115088 5255.720832 5093.138382 5105.288092 5176.476239 4932.002132 6189.510335 5012.937267 5106.076983 1.02996105 1.018416899 1.02930701 0.997466039 0.9998455 1.013787347 0.965908299 1.21218508 0.981759046 1 12.31799957 -4.253470922 24.99646566 1.011205249 1.212185177 0.903809358 0.020249425 201.7351173 632813.7213 0.002607516 0.038088754 5.58E-05 4.253470922 0.200979928 VEGDLKGPEVDIR ddPTM_HeLa_Curcumin_4h_R1 1 VEGDLKGPEVDIR 13 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 90.793 0.010145 5975800 5109.9 5262.3 5294.2 5821.3 4957.7 6822 5261.1 4962.4 5965.3 4874.9 FALSE FALSE TRUE 4705.446023 5717.149764 5490.407709 5797.213003 4898.582665 5407.0403 5408.712306 6475.412916 5310.921514 5044.302412 0.932823935 1.133387592 1.088437461 1.149259606 0.971112012 1.071910417 1.072241881 1.283708308 1.052855495 1 12.30043905 -7.260274844 24.99940512 0.968277968 1.102428202 0.279359599 0.080444398 76.69222439 1646377.565 0.012668599 0.015059203 5.49E-08 7.260274844 0.134150234 VEGIYTYSLS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 VEGIYTYSLSPSK 13 0 O95197-7;O95197-2;O95197 O95197-7 RTN3 Reticulon-3 1 0 VEGIYT(0.001)YS(0.238)LS(0.668)PS(0.093)K 112.72 0.0036041 0 925.34 924.63 792.11 823.06 1006.1 1068.5 1040.6 907.25 898.12 929.27 TRUE FALSE FALSE 852.0983626 1004.550897 821.4662934 819.6543958 994.1029146 846.8810555 1069.796435 1183.866349 799.598483 961.5620633 0.886160546 1.04470729 0.854303976 0.852419648 1.033841655 0.880734679 1.112560984 1.231190782 0.831562011 1 9.909236168 -4.574621465 3.850643886 0.941853003 1.212614262 0.636597761 0.07634742 0.094273303 2.79630832 0.009758414 0.046530492 2.66E-05 4.574621465 0.270761259 VEGQATDEKK(ac)EPK ddPTM_HeLa_Curcumin_4h_R1 2 VEGQATDEKKEPK 13 2 F8VXC8;Q8TAQ2-2;Q8TAQ2-3;Q8TAQ2 F8VXC8 SMARCC2 SWI/SNF complex subunit SMARCC2 0 1 ; VEGQATDEK(0.376)K(0.624)EPK;VEGQATDEK(0.372)K(0.628)EPK 85.909 0.0060457 7402400 5310.1 4626.1 4451.7 4624.4 6252 6882.2 3882.8 3389.7 4456.8 4039.3 FALSE TRUE FALSE 4889.799982 5025.95947 4616.683918 4605.265458 6177.448983 5454.754142 3991.740918 4423.203926 3967.90019 4179.665374 1.169902263 1.202478912 1.104558261 1.101826353 1.477976926 1.305069582 0.955038397 1.058267476 0.949334417 1 12.02917173 -9.062446808 0.66184152 0.98793642 1.178210506 0.243660422 0.136198632 1.240732324 0.908273905 0.131860762 0.031777131 8.66E-10 9.062446808 0.190274086 SASVVSSDSISTSADNFS(ph)PDLR ddPTM_HeLa_Curcumin_4h_R1 5 SASVVSSDSISTSADNFSPDLR 22 0 Q13614 Q13614 MTMR2 Myotubularin-related protein 2 1 0 SASVVSSDSISTSADNFS(1)PDLR;SASVVSSDSISTS(0.001)ADNFS(0.999)PDLR;SASVVSSDSISTSADNFS(1)PDLR;SASVVSSDSIS(0.006)T(0.019)S(0.108)ADNFS(0.868)PDLR;SASVVS(0.023)S(0.02)DS(0.001)IS(0.06)T(0.06)S(0.015)ADNFS(0.822)PDLR ;;;; 410.78 0 262263000 18298.23 15147.2 15154.85 16820.01 16272.97 18660.34 14076.1 5963.77 18049.59 15639.39 TRUE FALSE FALSE 16849.90579 16456.45647 15716.50207 16750.41326 16078.92546 14789.97514 14471.03748 7782.096019 16069.59513 16182.85764 1.041219429 1.016906707 0.971182125 1.035071409 0.993577638 0.91392852 0.894220156 0.480885156 0.993001081 1 13.98217877 -4.013982055 1.314553121 1.014197609 1.30E-14 0.958913755 0.031962784 0.303791642 0.296095407 0.00464561 0.479800468 9.68E-05 4.013982055 -1.014197609 down VEIGQK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 VEIGQKR 7 1 H0YER7;G3V1C3;Q9BZZ5-1;Q9BZZ5-5;Q9BZZ5-2;Q9BZZ5-6;Q9BZZ5 H0YER7 API5 Apoptosis inhibitor 5 0 1 ; VEIGQK(1)R;VEIGQK(1)R 143.11 0.0010119 22750000 9466.1 7839.2 8589.8 8275.3 7349.8 9513.5 6315 9086.4 8661.1 7634.5 FALSE TRUE FALSE 8716.848196 8516.785517 8908.145544 8241.059001 7262.158435 7540.292861 6492.181904 11856.80153 7710.998999 7899.798307 1.103426677 1.078101641 1.12764215 1.043198659 0.919284031 0.95449182 0.821816159 1.500899272 0.976100743 1 12.9476001 -5.994016004 24.8533201 1.059301179 1.020516553 0 0.173858172 809.8138297 3363362.356 0.023685002 0.042847236 1.01E-06 5.994016004 -0.038784626 VEILANDQGNR ddPTM_HeLa_Curcumin_4h_R1 3 VEILANDQGNR 11 0 P17066;P48741 P17066 HSPA6;HSPA7 Heat shock 70 kDa protein 6;Putative heat shock 70 kDa protein 7 0 0 ;; ;; 188.99 5.84E-13 157513000 11325.2 9548.6 9825.8 10931.3 9738.2 11858 9693.7 9067.5 10548 9516.9 FALSE FALSE TRUE 10428.79847 10373.93844 10189.95279 10886.06918 9622.078325 9398.517133 9965.679133 11832.13901 9390.91079 9847.611567 1.059018057 1.05344716 1.034763884 1.105452739 0.977097671 0.954395598 1.011989462 1.201523733 0.953623193 1 13.26555814 -11.86598762 0.005807709 2.23E-05 2.011695991 0.125591985 0.067325234 62006.92336 39.74011138 7307.571192 6479.969311 1.36E-12 11.86598762 2.011673692 VEKEEAGGGIS(ph)EEEAAQYDR ddPTM_HeLa_Curcumin_4h_R1 1 VEKEEAGGGISEEEAAQYDR 20 1 A0A590UK93;A0A590UKC5;B3KNJ4;Q9UBE0-2;Q9UBE0-3;Q9UBE0;M0R375;M0QZS6 A0A590UK93 SAE1 "SUMO-activating enzyme subunit 1;SUMO-activating enzyme subunit 1, N-terminally processed" 1 0 VEKEEAGGGIS(0.998)EEEAAQY(0.002)DR 60.814 0.0069151 3116500 975.09 758.4 952.51 1160.8 870.59 1257 722.88 673.52 1239 742.86 TRUE FALSE FALSE 897.9105976 823.9527166 987.8108585 1155.996917 860.2087829 996.2840307 743.1620673 878.8731475 1103.0848 768.6743297 1.168128768 1.071913923 1.285083709 1.503883859 1.119080929 1.296106806 0.96681005 1.143362167 1.435048313 1 9.586228679 -8.68498175 0.660122818 1.001178201 1.202732508 0 0.19166506 0.888666335 0.75587861 0.091079523 0.033385895 2.07E-09 8.68498175 0.201554308 VELDNMPLR ddPTM_HeLa_Curcumin_4h_R1 1 VELDNMPLR 9 0 Q15233;Q15233-2;C9IZL7;C9JYS8;C9J4X2 Q15233 NONO Non-POU domain-containing octamer-binding protein 0 0 106.68 0.0047041 2024600 3257.8 2291.6 2641.3 2814.8 2952.1 3758.1 2450.7 2163.6 3010.3 2483.2 FALSE FALSE TRUE 2999.941692 2489.675693 2739.188902 2803.153103 2916.898136 2978.627697 2519.460046 2823.27168 2680.077621 2569.491015 1.167523714 0.968937302 1.066043386 1.09093711 1.135204645 1.159228688 0.980528841 1.098766901 1.043038332 1 11.32726689 -9.688349357 1.56585241 1.000060451 1.094342829 0.097855212 0.065005732 0.500030923 2.211614628 0.048195049 0.010725617 2.05E-10 9.688349357 0.094282378 VELQELNDR ddPTM_HeLa_Curcumin_4h_R1 5 VELQELNDR 9 0 P08670;B0YJC4;A0A1B0GTT5;P17661 P08670 VIM;DES Vimentin;Desmin 0 0 ;;;; ;;;; 163.88 2.22E-05 271292000 12336.7 10921.1 12133.3 11719.4 14263.5 14334.3 12361 12268.3 10911 10411.5 FALSE FALSE TRUE 11360.23718 11865.07122 12582.97077 11670.90823 14093.41708 11361.2046 12707.81639 16008.84819 9714.090598 10773.29885 1.054480836 1.101340582 1.167977511 1.083317969 1.308180277 1.054570634 1.179565941 1.485974576 0.901682088 1 13.39517246 -1 0.258767088 1.008499528 3.442539025 0.619663843 0.096658974 22.82536637 0.287156507 0.043671921 24.76670022 0.1 1 2.434039497 VELS(ph)PGPPKPAGR ddPTM_HeLa_Curcumin_4h_R1 1 VELSPGPPKPAGR 13 1 A0A087WXE2;Q8IZ73-2;Q8IZ73 A0A087WXE2 RPUSD2 RNA pseudouridylate synthase domain-containing protein 2 1 0 VELS(1)PGPPKPAGR 69.045 0.016212 118250000 6436.6 5848.1 6539.8 6126.3 6401.8 7851.6 5835.5 3627.4 6375 5871 TRUE FALSE FALSE 5927.136318 6353.583705 6782.170741 6100.950994 6325.462716 6223.089654 5999.228425 4733.377562 5675.678449 6075.016813 0.975657599 1.045854506 1.116403617 1.004268989 1.041225549 1.024374063 0.98752458 0.779154644 0.934265472 1 12.56867269 -4.262860357 4.069391885 1.008305344 0.759685596 0.703001024 0.045911821 0.097611754 3.443549355 0.006277827 0.07088025 5.46E-05 4.262860357 -0.248619748 VEMY(ph)S(ph)GSDDDDDFNKLPKK ddPTM_HeLa_Curcumin_4h_R1 2 VEMYSGSDDDDDFNKLPKK 19 2 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 2 0 VEMY(0.667)S(0.667)GS(0.667)DDDDDFNKLPKK;VEMY(0.876)S(0.876)GS(0.249)DDDDDFNKLPKK ; 75.574 0.0026868 63438000 9036.5 6474.8 7268.4 6997.2 6001.1 9118.6 6439.2 7192.9 9684.8 8536.9 TRUE FALSE FALSE 8321.25149 7034.452861 7537.773298 6968.24744 5929.540802 7227.299572 6619.866622 9385.982098 8622.40167 8833.55664 0.942004657 0.796333023 0.853311255 0.788838259 0.671251801 0.818164174 0.749399918 1.06253715 0.976096268 1 13.10877871 -7.398575534 2.045873882 0.97864956 0.809725664 0.344863907 0.095516436 0.230694894 1.846793302 0.017168582 0.019356619 3.99E-08 7.398575534 -0.168923896 VEMYS(ph)GS(ph)DDDDDFNKLPK ddPTM_HeLa_Curcumin_4h_R1 1 VEMYSGSDDDDDFNKLPK 18 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 2 0 VEMY(0.132)S(0.934)GS(0.934)DDDDDFNKLPK 63.062 0.016942 16238000 2451.1 2042.7 2306.1 2394.2 2355.3 2763.6 1960.6 1789.2 2587.9 2313.5 TRUE FALSE FALSE 2257.092849 2219.261886 2391.566095 2384.293435 2327.214586 2190.398208 2015.609159 2334.718844 2304.013845 2393.893953 0.94285415 0.927051043 0.999027585 0.995989581 0.972146065 0.914993835 0.841979302 0.975280814 0.962454432 1 11.22514353 -3.130688989 0.010176679 1.826680915 4.75E-08 0.132195983 0.043369166 8105.068028 9.639320958 782.8942255 954.905379 0.000740135 3.130688989 -1.826680868 VEMYSGS(ph)DDDDDFNKLPK ddPTM_HeLa_Curcumin_4h_R1 1 VEMYSGSDDDDDFNKLPK 18 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 0 VEMYS(0.139)GS(0.861)DDDDDFNKLPK 86.727 0.0017582 32193000 1153.2 777.7 1004.8 1048.6 876.63 1088.7 839.14 1456.2 1075.8 943.26 TRUE FALSE FALSE 1061.923003 844.9209226 1042.038772 1044.261171 866.1767598 862.8913478 862.68401 1900.188676 957.7874315 976.0382148 1.087993264 0.865663772 1.067620874 1.069897833 0.887441441 0.884075372 0.883862944 1.9468384 0.981301159 1 9.930793824 -4.256921188 24.99751963 1.005571075 1.946838778 0.915238008 0.088602699 103.4742555 572465.0271 0.01335214 0.142113245 5.53E-05 4.256921188 0.941267702 VENMSSNQDGNDS(ph)DEFM ddPTM_HeLa_Curcumin_4h_R1 14 VENMSSNQDGNDSDEFM 17 0 Q86WR0-2;Q86WR0 Q86WR0-2 CCDC25 Coiled-coil domain-containing protein 25 1 0 VENMSSNQDGNDS(1)DEFM;VENMS(0.001)S(0.004)NQDGNDS(0.995)DEFM;VENMSSNQDGNDS(1)DEFM;VENMSSNQDGNDS(1)DEFM;VENMSSNQDGNDS(1)DEFM;VENMSSNQDGNDS(1)DEFM;VENMSSNQDGNDS(1)DEFM;VENMSSNQDGNDS(1)DEFM;VENMSSNQDGNDS(1)DEFM;VENMSSNQDGNDS(1)DEFM;VENMSSNQDGNDS(1)DEFM;VENMSSNQDGNDS(1)DEFM;VENMSSNQDGNDS(1)DEFM;VENMSSNQDGNDS(1)DEFM ;;;;;;;;;;;;; 167.92 8.68E-05 245135400 26861.5 21608.84 23128.44 23953.07 23921.91 27450.15 22414.86 19272.56 26914.82 23692.18 TRUE FALSE FALSE 24735.38393 23476.61184 23985.60033 23853.95854 23636.65685 21756.67946 23043.76065 25148.67482 23962.33158 24515.48149 1.008969942 0.957623935 0.978385856 0.973016114 0.964152258 0.887466945 0.939967696 1.025828305 0.97743671 1 14.58140548 -6.870413286 1.046729004 1.004600996 0.95253031 0.128745533 0.034365064 0.435450339 0.945821358 0.006576474 0.00955879 1.35E-07 6.870413286 -0.052070686 VEPEVLSTDTQT(ph)SPEPGTR ddPTM_HeLa_Curcumin_4h_R1 1 VEPEVLSTDTQTSPEPGTR 19 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 0 VEPEVLST(0.002)DT(0.011)QT(0.541)S(0.354)PEPGT(0.091)R 114.4 0.00095907 7429200 1165.9 604.49 955.87 1002.5 1121.2 1309.5 776.43 489.5 972.17 883.07 TRUE FALSE FALSE 1073.617785 656.739422 991.2953831 998.3519206 1107.830422 1037.894939 798.2145361 638.7462966 865.5253832 913.7566168 1.174949396 0.718724669 1.084857132 1.092579689 1.212391136 1.135854909 0.873552674 0.699033293 0.947216543 1 9.835666138 -4.538341971 3.509878269 1.070950088 0.719097814 0.389404117 0.134902334 0.160341374 3.997142723 0.018850362 0.104170229 2.90E-05 4.538341971 -0.351852274 VEPEVLSTDTQTS(ph)PEPGTR ddPTM_HeLa_Curcumin_4h_R1 1 VEPEVLSTDTQTSPEPGTR 19 0 P29375;P29375-2 P29375 KDM5A Lysine-specific demethylase 5A 1 0 VEPEVLSTDTQT(0.084)S(0.916)PEPGTR 180.39 3.09E-07 8327700 3521.1 2202.9 2843.4 3563.5 2478.4 4042.5 2363.3 1132.7 3531.7 3172 TRUE FALSE FALSE 3242.40122 2393.30886 2948.778905 3548.755181 2448.846699 3204.039932 2429.607838 1478.055016 3144.281346 3282.226764 0.987866303 0.729172307 0.898408037 1.081203535 0.746093087 0.976178723 0.74023156 0.45032081 0.957972003 1 11.6804592 -4.037716426 1.056063562 0.963310074 1.23E-20 0.618525256 0.110765165 1.193498644 0.768516001 0.016707261 1.437471926 9.17E-05 4.037716426 -0.963310074 VEPGLGADNSVVR ddPTM_HeLa_Curcumin_4h_R1 2 VEPGLGADNSVVR 13 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 132.03 0.0012214 26979000 3092.5 3021.8 3019.7 3062 3376.3 3784.8 2972.8 3153.1 2965.1 2797.6 FALSE FALSE TRUE 2847.725362 3282.990927 3131.612738 3049.330255 3336.039828 2999.789817 3056.208767 4114.465675 2639.835948 2894.816392 0.983732637 1.134092973 1.081800126 1.05337605 1.152418453 1.03626255 1.055752198 1.42132181 0.911918267 1 11.49925613 -1.827146864 1.24147536 1.023337577 200 0.710495112 0.070505707 286.9759772 1.139616938 0.010359888 161823.4684 0.014888575 1.827146864 198.9766624 VEPSSQS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 1 VEPSSQSPGR 10 0 X6RM00;G8JLD3;X6RLX0;Q8IUD2-5;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 0 VEPS(0.001)S(0.006)QS(0.993)PGR 111.72 0.0068673 100130000 1385 1298.9 1482.2 1571.1 1849.5 2435.2 1824.3 661.68 1108.1 1046.5 TRUE FALSE FALSE 1275.375789 1411.171128 1537.131636 1564.599204 1827.44592 1930.11207 1875.484948 863.423186 986.5442023 1082.865797 1.177778255 1.30318192 1.419503359 1.444868984 1.687601479 1.782411149 1.731964342 0.797350132 0.91104937 1 10.08063874 -7.142201656 0.920218901 1.053003724 1.531767968 0.367284688 0.26467352 0.391534006 0.657601874 0.056148485 0.071310185 7.21E-08 7.142201656 0.478764245 VEPSSQS(ph)PGRSPR ddPTM_HeLa_Curcumin_4h_R1 1 VEPSSQSPGRSPR 13 1 X6RM00;G8JLD3;X6RLX0;Q8IUD2-5;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 0 VEPSS(0.059)QS(0.68)PGRS(0.26)PR 172.09 0.0019302 6259200 2567 1784.3 2066.2 2654.5 2205.1 2018.1 1567.3 902.75 2335.3 2142.1 TRUE FALSE FALSE 2363.819241 1938.526941 2142.77519 2643.516382 2178.805623 1599.523311 1611.27422 1177.994319 2079.123433 2216.537816 1.066446611 0.87457427 0.966721693 1.192633107 0.982976969 0.721631411 0.726932881 0.531456901 0.938004945 1 11.11409226 -5.170719999 2.476707509 1.026294715 0.634432633 0.750336581 0.091365703 0.09919613 1.174270551 0.01265296 0.038970761 6.75E-06 5.170719999 -0.391862082 VEPSSQSPGRS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 VEPSSQSPGRSPR 13 1 X6RM00;G8JLD3;X6RLX0;Q8IUD2-5;Q8IUD2-4;Q8IUD2-2;Q8IUD2-3;Q8IUD2;K7EKH8;K7EIZ7 X6RM00 ERC1 ELKS/Rab6-interacting/CAST family member 1 1 0 VEPSSQSPGRS(1)PR;VEPSSQSPGRS(1)PR;VEPSSQS(0.012)PGRS(0.988)PR ;; 142.57 0.00038481 391545700 12784.8 11542 11441.8 13151.3 12262.8 11427.8 7768.7 4720.54 12401.1 9712.9 TRUE FALSE FALSE 11772.86959 12539.63905 11865.84317 13096.88341 12116.57412 9057.545462 7986.668814 6159.810915 11040.73036 10050.42255 1.171380559 1.24767282 1.180631273 1.303117689 1.205578577 0.901210413 0.794660003 0.61289074 1.098533947 1 13.29496854 -4.855102992 2.045591159 1.126613825 0.657237709 0.799883044 0.094088957 0.150883387 1.197196291 0.017288935 0.084648704 1.40E-05 4.855102992 -0.469376116 VEPTLVTENS(ph)GNK ddPTM_HeLa_Curcumin_4h_R1 1 VEPTLVTENSGNK 13 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 0 VEPTLVT(0.01)ENS(0.99)GNK 124.42 0.0020994 4970500 1252.2 1410.9 1603.4 1351.7 1775.5 1730.5 1235 857.4 1473.7 1422.6 TRUE FALSE FALSE 1153.087049 1532.851909 1662.823414 1346.107024 1754.328322 1371.574793 1269.650776 1118.817313 1312.038797 1472.035244 0.783328425 1.04131468 1.129608426 0.914452985 1.191770597 0.931754045 0.862513844 0.760047912 0.891309364 1 10.5235965 -2.049062949 12.55714154 0.932276783 0.441747133 0 0.1347086 0 0 0.019469037 0 0.00893176 2.049062949 -0.49052965 VEQATKPS(ph)FESGR ddPTM_HeLa_Curcumin_4h_R1 2 VEQATKPSFESGR 13 1 P38159;P38159-2;H0Y6E7;H3BT71 P38159 RBMX "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed" 1 0 VEQATKPS(1)FESGR;VEQAT(0.251)KPS(0.739)FES(0.01)GR ; 179.65 0.0015208 91690000 7563.5 5832.4 6525.2 6694.6 7594.7 7472 6402.8 2706.31 6875.9 6144.5 TRUE FALSE FALSE 6964.840994 6336.526667 6767.029652 6666.899519 7504.138163 5922.222973 6582.445336 3531.451461 6121.630973 6358.020918 1.095441661 0.996619349 1.064329567 1.048580935 1.180263208 0.931456982 1.035297842 0.555432501 0.9628202 1 12.63436205 -4.258378687 5.455224382 1.045757788 0.536206372 0.819380034 0.067384917 0.042844155 4.752163302 0.008597983 0.080818143 5.52E-05 4.258378687 -0.509551416 VEQATKPSFESGR ddPTM_HeLa_Curcumin_4h_R1 1 VEQATKPSFESGR 13 1 P38159;P38159-2;H0Y6E7;H3BT71 P38159 RBMX "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed" 0 0 87.216 0.01179 5133600 2095.1 2218.7 2404.1 2303.6 2617.6 2874.3 2864.3 2328.6 2224.4 2180.4 FALSE FALSE TRUE 1929.270624 2410.474542 2493.198061 2294.068314 2586.38683 2278.13778 2944.664549 3038.57942 1980.388885 2256.168738 0.855109191 1.068392847 1.105058331 1.016798201 1.146362321 1.009737322 1.305161489 1.346787308 0.8777663 1 11.13965925 -2.965761811 0.380053031 0.937524911 2.411724427 0.710641608 0.082175461 5.802357741 0.27267283 0.024942909 4.832441114 0.001082027 2.965761811 1.474199515 VEQFPDASGSLK ddPTM_HeLa_Curcumin_4h_R1 2 VEQFPDASGSLK 12 0 Q96L96 Q96L96 ALPK3 Alpha-protein kinase 3 0 0 ; ; 104.82 0.0056822 45101000 4244.4 4032.6 3244.2 3931.7 4008 4793.7 3573.1 2004.48 4096.8 4187.4 FALSE FALSE TRUE 3908.451261 4381.159975 3364.432906 3915.431667 3960.207218 3799.432584 3673.351569 2615.636725 3647.39129 4332.911838 0.902038031 1.011135269 0.776483121 0.90364905 0.913982875 0.876877427 0.847778978 0.603667192 0.841787561 1 12.08112117 -3.637718745 0.843905148 0.941077359 3.42E-44 0.591207213 0.070584971 2.586196273 0.64587009 0.010738215 2.911833811 0.000230293 3.637718745 -0.941077359 PGWLSS(ph)PTLGR ddPTM_HeLa_Curcumin_4h_R1 2 PGWLSSPTLGR 11 0 C9JS59;C9J266;Q5XPI4;Q5XPI4-2 C9JS59 RNF123 E3 ubiquitin-protein ligase RNF123 1 0 PGWLS(0.006)S(0.961)PT(0.033)LGR;PGWLS(0.038)S(0.925)PT(0.037)LGR ; 131.42 0.0026326 138008000 8634.9 7096.8 7852.2 8512 7597.7 7234.8 6427.4 2726.6 7194.5 7556.6 TRUE FALSE FALSE 7951.438553 7710.215769 8143.209439 8476.779599 7507.10239 5734.220927 6607.735546 3557.927788 6405.28135 7819.191288 1.016913164 0.98606307 1.041438832 1.084099274 0.960086806 0.733352174 0.845066363 0.455025035 0.819174402 1 12.93280369 -4.011242208 0.786399084 1.014264151 1.59E-12 0.73917771 0.091865307 0.879668783 0.300162674 0.010504901 0.853625923 9.74E-05 4.011242208 -1.014264151 down VERADGYEPPVQES(ph)V ddPTM_HeLa_Curcumin_4h_R1 1 VERADGYEPPVQESV 15 1 P61247;H0Y9Y4;D6RAT0;D6R9B6 P61247 RPS3A 40S ribosomal protein S3a 1 0 VERADGYEPPVQES(1)V 122.16 0.01109 8979100 2641 1963 1660.8 2257.4 1521.2 2349.8 1387.8 1556.1 2849.9 2634 TRUE FALSE FALSE 2431.962063 2132.672973 1722.350709 2248.059477 1503.060684 1862.424992 1426.737933 2030.547727 2537.2731 2725.531304 0.892289169 0.782479721 0.631932096 0.824815137 0.551474379 0.683325482 0.52347149 0.745009872 0.930927888 1 11.41232178 -7.14389626 0.665648874 0.981560764 0.625945587 0.687975519 0.084869038 0.213621826 0.200553361 0.020956213 0.027122089 7.18E-08 7.14389626 -0.355615177 VERPPS(ph)PFSMAPQASLPPVPPR ddPTM_HeLa_Curcumin_4h_R1 2 VERPPSPFSMAPQASLPPVPPR 22 1 A0A1B0GW38;A0A0U1RQX8;P22681 A0A1B0GW38 CBL E3 ubiquitin-protein ligase CBL 1 0 VERPPS(0.98)PFS(0.018)MAPQAS(0.002)LPPVPPR;VERPPS(0.987)PFS(0.013)MAPQASLPPVPPR ; 90.765 0.00013677 91051000 668.63 729.15 1051.03 863.06 942.45 1091.66 783.3 430.42 1284.61 856.32 TRUE FALSE FALSE 615.70723 792.174477 1089.982096 859.4888864 931.2118993 865.2374105 805.2772899 561.6530766 1143.691497 886.0770563 0.69486872 0.894024364 1.230121115 0.969993389 1.050937831 0.976481001 0.908811806 0.633864823 1.290735934 1 9.791288356 -1.419411306 21.65849798 0.898917335 0.024716051 0 0.204847293 0 0 0.024542946 0 0.03807051 1.419411306 -0.874201284 VES(ph)EES(ph)GDEEGKK ddPTM_HeLa_Curcumin_4h_R1 2 VESEESGDEEGKK 13 1 H7C118;C9JRC4;B5MBZ8;C9JD73;Q15435-3;Q15435;H7C003 H7C118 PPP1R7 Protein phosphatase 1 regulatory subunit 7 2 0 VES(1)EES(1)GDEEGKK;VES(1)EES(1)GDEEGKK ; 99.991 0.005701 67657000 9691.3 9099 9631.5 8748.4 10415 9408.6 8026.2 7481 8135.9 8160.8 TRUE FALSE FALSE 8924.223379 9885.477016 9988.451863 8712.201439 10290.80793 7457.150303 8251.393571 9761.922462 7243.412125 8444.387193 1.056823092 1.170656531 1.182851003 1.03171506 1.218656569 0.883089576 0.977145337 1.156024971 0.857778304 1 13.04377702 -3.571654781 4.595208109 1.048708526 11.16828476 0.077549563 0.11556087 1762.888453 303.0557502 0.013821303 183763.3541 0.00026813 3.571654781 10.11957624 VESEES(ph)GDEEGKK ddPTM_HeLa_Curcumin_4h_R1 1 VESEESGDEEGKK 13 1 H7C118;C9JRC4;B5MBZ8;C9JD73;Q15435-3;Q15435;H7C003 H7C118 PPP1R7 Protein phosphatase 1 regulatory subunit 7 1 0 VESEES(1)GDEEGKK 143.56 6.69E-05 0 2016.5 2510.6 2373.9 1994.2 2531.2 2425.9 1800.2 2114.4 1991.1 2497.2 TRUE FALSE FALSE 1856.891897 2727.605077 2461.878822 1985.948529 2501.017093 1922.740994 1850.708767 2759.070826 1772.681311 2583.977514 0.718617669 1.055583906 0.952747773 0.76856262 0.967894295 0.744101287 0.716224796 1.067761159 0.686028149 1 11.3353778 -5.262509269 24.82396622 0.883584192 0.830048663 0.009509854 0.145379057 323.0024255 7494523.234 0.020898821 0.049356415 5.46E-06 5.262509269 -0.053535529 VESGYFS(ph)LEK ddPTM_HeLa_Curcumin_4h_R1 2 VESGYFSLEK 10 0 A0A494BZV2;Q6WCQ1;Q6WCQ1-2;A0A1W2PPU9;J3KSW8;Q6WCQ1-3 A0A494BZV2 MPRIP Myosin phosphatase Rho-interacting protein 1 0 VES(0.001)GYFS(0.999)LEK;VESGYFS(1)LEK ; 149.49 0.00083171 42369000 5242.4 4091.5 4110.2 4601.1 4839.4 5648.6 4761.7 2425.1 5509.9 4273.7 TRUE FALSE FALSE 4827.458508 4445.151029 4262.527628 4582.061867 4781.693316 4477.016687 4895.300487 3164.501826 4905.477755 4422.210757 1.091639176 1.005187512 0.963890656 1.03614733 1.081290237 1.012393333 1.106980367 0.715592721 1.109281765 1 12.11055207 -4.254082931 24.99379033 1.03943471 0.715592567 0.808455775 0.048057404 285.4537877 969815.593 0.006570271 0.091588315 5.57E-05 4.254082931 -0.323842143 VESLESLYFT(ph)PIPAR ddPTM_HeLa_Curcumin_4h_R1 2 VESLESLYFTPIPAR 15 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 VESLESLYFT(0.999)PIPAR;VESLES(0.001)LYFT(0.999)PIPAR ; 153.24 3.31E-06 1463900 1822.09 1520.21 1784.11 1860.22 2163.9 2268.4 2067.42 1512.38 1575.21 1288.36 TRUE FALSE FALSE 1677.869654 1651.610178 1850.230686 1852.522903 2138.096906 1797.90827 2125.426241 1973.4977 1402.413404 1333.130414 1.258593785 1.238896181 1.387884236 1.38960366 1.603816763 1.348636451 1.594312318 1.480348568 1.051970152 1 10.3806022 -7.53513244 0.261268878 0.915566921 1.609643556 0.836672088 0.078156547 0.443993726 0.11214634 0.119102398 0.105284636 2.92E-08 7.53513244 0.694076636 VET(ph)PSHPGGVSEEFWER ddPTM_HeLa_Curcumin_4h_R1 1 VETPSHPGGVSEEFWER 17 0 Q92620;H3BQT9 Q92620 DHX38 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 1 0 VET(0.781)PS(0.219)HPGGVSEEFWER 86.258 0.00589 6569700 2075.7 2271.2 1913.4 1786.5 2238.2 3225.6 2282 1297.5 2268.2 2003.1 TRUE FALSE FALSE 1911.406155 2467.512408 1984.312287 1779.107936 2211.510927 2556.5742 2346.026778 1693.101777 2019.384135 2072.707576 0.922178399 1.190477825 0.957352745 0.858349705 1.066967165 1.233446642 1.131865781 0.816855111 0.974273534 1 11.01730088 -5.555081337 24.99366969 0.973817966 1.081565262 0.074932281 0.126320002 281.3389061 218357.0963 0.017971301 0.035942751 2.79E-06 5.555081337 0.107747296 VETFSGVYK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VETFSGVYKK 10 1 P62081;A0A2R8Y623 P62081 RPS7 40S ribosomal protein S7 0 1 ; VETFSGVYK(1)K;VETFSGVYK(1)K 179.81 1.39E-32 6473500 2870.6 3440.2 2648.4 2860.8 5320.9 6262.4 5324.8 4130.3 5934.1 2718.6 FALSE TRUE FALSE 2643.388981 3737.555559 2746.552034 2848.962768 5257.451743 4963.507648 5474.199557 5389.609456 5283.144076 2813.071148 0.939680812 1.32863883 0.976353562 1.012758874 1.868936641 1.764444405 1.945986884 1.91591651 1.878069839 1 11.45793033 -5.762188737 8.876606872 1.00331068 1.872080182 0.506218975 0.299134828 0.019364768 17.32628382 0.01732231 0.032964244 1.73E-06 5.762188737 0.868769502 VETGVLKPGMVVTFAPVNVT(ph)TEVK ddPTM_HeLa_Curcumin_4h_R1 1 VETGVLKPGMVVTFAPVNVTTEVK 24 1 Q5VTE0;P68104;A0A087WVQ9 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1 1 0 VETGVLKPGMVVTFAPVNVT(0.962)T(0.038)EVK 113.34 1.08E-06 11919000 1572.3 1252.9 1274.8 1442.6 1594.5 2274.7 1391 1017.4 1765.1 1405.7 TRUE FALSE FALSE 1447.850796 1361.195093 1322.045209 1436.630903 1575.486629 1802.901579 1430.027716 1327.600576 1571.472946 1454.54797 0.995395701 0.935820008 0.908904509 0.987682038 1.083145184 1.239492692 0.983142354 0.912723818 1.080385782 1 10.50635516 -5.773321506 22.71850884 0.984563865 1.06272479 0.128024553 0.088399666 102.4812498 195944.268 0.012604667 0.023013743 1.69E-06 5.773321506 0.078160925 VETGVLKPGMVVTFAPVNVTTEVK ddPTM_HeLa_Curcumin_4h_R1 2 VETGVLKPGMVVTFAPVNVTTEVK 24 1 Q5VTE0;P68104;A0A087WVQ9 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1 0 0 ; ; 114.88 2.84E-07 11332840 2714.72 2359.25 2056.64 1991.17 2347.14 3072.15 2274.82 1900.21 2367.2 2444 FALSE FALSE TRUE 2499.847047 2563.173057 2132.860888 1982.931066 2319.151888 2434.95146 2338.645327 2479.575282 2107.524082 2528.928818 0.98850036 1.013541006 0.843385101 0.784099201 0.917049097 0.962839065 0.924757277 0.980484411 0.833366312 1 11.30431071 -6.777163654 24.99793832 0.995840745 0.9012085 0.039517367 0.073979074 182.2321067 289705.9772 0.009163653 0.012066098 1.67E-07 6.777163654 -0.094632245 VETLS(ph)PESALQGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 5 VETLSPESALQGSPR 15 0 Q99958 Q99958 FOXC2 Forkhead box protein C2 2 0 VET(0.006)LS(0.99)PES(0.004)ALQGS(1)PR;VET(0.114)LS(0.886)PESALQGS(1)PR;VET(0.01)LS(0.988)PES(0.002)ALQGS(1)PR;VET(0.013)LS(0.978)PES(0.009)ALQGS(1)PR;VETLS(0.993)PES(0.006)ALQGS(1)PR ;;;; 185.71 5.13E-05 329799700 21672.4 17020.6 17951 17264.7 19834 22313.6 15706.9 6763.13 17343.9 16519 TRUE FALSE FALSE 19957.00667 18491.78482 18616.27985 17193.26325 19597.4925 17685.50783 16147.59334 8825.177203 15441.31756 17093.03402 1.167552036 1.081831628 1.089115006 1.005863747 1.146519248 1.034661711 0.944688539 0.516302559 0.90336903 1 14.06112088 -4.161415938 1.784960277 1.080007047 0.223612327 0.818014953 0.07517837 0.300780228 0.774120217 0.009547757 0.468947456 6.90E-05 4.161415938 -0.85639472 VETLSPESALQGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 3 VETLSPESALQGSPR 15 0 Q99958 Q99958 FOXC2 Forkhead box protein C2 1 0 VETLSPESALQGS(1)PR;VETLSPESALQGS(1)PR;VETLSPES(0.003)ALQGS(0.997)PR ;; 239.51 5.72E-29 125260000 4858.71 3902.17 4282.85 4229.06 4410.83 4718.23 4286.57 2562.66 4132.78 3605.65 TRUE FALSE FALSE 4474.137977 4239.456187 4441.576189 4211.56127 4358.233733 3739.615913 4406.839617 3344.003237 3679.424374 3730.946069 1.199196636 1.136295221 1.190469148 1.128818587 1.168130992 1.002323765 1.181158756 0.896288281 0.986190716 1 11.86532579 -4.249124719 24.14131058 1.110552775 0.896288065 0.395700581 0.079336306 1048.094618 2054594.791 0.011942132 0.264156913 5.63E-05 4.249124719 -0.21426471 VETMLRNDS(ph)LSS(ph)DQS(ph)ES(ph)VRPSPPK ddPTM_HeLa_Curcumin_4h_R1 1 VETMLRNDSLSSDQSESVRPSPPK 24 2 H0YBU6;Q86UR5-2;Q86UR5-8;Q86UR5-7;Q86UR5-6;Q86UR5-5;Q86UR5-3;Q86UR5-4;Q86UR5 H0YBU6 RIMS1 Regulating synaptic membrane exocytosis protein 1 4 0 VET(0.013)MLRNDS(0.943)LS(0.441)S(0.807)DQS(0.788)ES(0.788)VRPS(0.22)PPK 45.992 0.0084784 0 234.82 194.93 128.12 322.83 241.02 220.3 289.99 352.87 335.28 270.72 TRUE FALSE FALSE 216.2337492 211.7788806 132.8682399 321.494215 238.1459939 174.6072967 298.1263389 460.4584386 298.5006228 280.1274998 0.771911895 0.756008891 0.474313446 1.147671025 0.850134293 0.623313658 1.06425231 1.643745933 1.06558843 1 8.129939808 -4.325853205 3.230916106 0.851078306 1.704419879 0.613982054 0.192557171 0.140305935 2.348158366 0.025863636 0.270859001 4.72E-05 4.325853205 0.853341573 VETPVLPPVLVPR ddPTM_HeLa_Curcumin_4h_R1 1 VETPVLPPVLVPR 13 0 P84022;H0YMP2;H0YL71;H3BP09;H3BVD1;K7EJX0;B7Z5N5;P84022-3;P84022-2;O15198-2;Q15796-2;Q15796;O15198 P84022 SMAD3;SMAD2;SMAD9 Mothers against decapentaplegic homolog 3;Mothers against decapentaplegic homolog;Mothers against decapentaplegic homolog 9;Mothers against decapentaplegic homolog 2 0 0 137.95 0.00073845 374300 141.01 0 154.49 81.959 157 164.44 216.99 142.08 181.77 178.49 FALSE FALSE TRUE 129.8489097 0 160.2155353 81.61987537 155.1278775 130.3332904 223.0781554 185.3995379 161.8302858 184.6925142 0.703054535 0 0.867471733 0.441923029 0.839925095 0.705677168 1.207835393 1.003828113 0.876214645 1 7.528981583 -2.927808911 15.1521274 0.795590333 1.108297597 0 0.323019636 0 0 0.043771982 0 0.00118084 2.927808911 0.312707264 VETSEGLNS(ph)DLEMHADK ddPTM_HeLa_Curcumin_4h_R1 2 VETSEGLNSDLEMHADK 17 0 P49454 P49454 CENPF Centromere protein F 1 0 VETSEGLNS(1)DLEMHADK;VET(0.017)S(0.017)EGLNS(0.966)DLEMHADK ; 129.2 9.78E-05 4453800 6013.6 5090.5 5296.4 5537.2 5067.4 5780.6 4633.9 2448.9 5138.4 4758.4 TRUE FALSE FALSE 5537.617214 5530.500137 5492.689243 5514.288534 5006.974565 4581.638399 4763.914762 3195.558337 4574.730376 4923.754046 1.124673808 1.123228351 1.115549069 1.119935822 1.016901843 0.930517316 0.967537111 0.649008522 0.929114317 1 12.26554298 -3.754220529 0.91743702 1.071392517 1.46E-16 0.750999739 0.069286679 1.583821072 0.528091427 0.01014124 2.115623874 0.000176108 3.754220529 -1.071392517 YYGGAGGS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 1 YYGGAGGSPGK 11 0 A0A1B0GTT1;A0A1B0GVM0;Q9BUH8 A0A1B0GTT1 BEGAIN Brain-enriched guanylate kinase-associated protein 1 0 YYGGAGGS(1)PGK 105.13 0.0085084 8488000 3898.1 3295.1 3882.3 3501.7 3313.2 4133.6 3445.6 1345.2 4369.1 3763.8 TRUE FALSE FALSE 3589.561272 3579.913761 4026.181453 3487.210893 3273.692254 3276.244765 3542.274263 1755.345287 3889.820661 3894.59177 0.921678441 0.919201285 1.033787799 0.895398311 0.840573916 0.841229314 0.90953673 0.450713551 0.99877494 1 11.9272564 -4.007759435 1.635469729 0.947012294 1.13E-34 0.829271986 0.064526073 0.639011518 0.962002597 0.009777235 1.163421638 9.82E-05 4.007759435 -0.947012294 down VEVERDNLAEDIMR ddPTM_HeLa_Curcumin_4h_R1 3 VEVERDNLAEDIMR 14 1 P08670;B0YJC4 P08670 VIM Vimentin 0 0 ;; ;; 150.11 0.00043956 224029100 9179 6836.6 7106.2 8580.8 6398.2 10054.2 7365.3 6694.2 10738 7864.4 FALSE FALSE TRUE 8452.472464 7427.525241 7369.562023 8545.294923 6321.905644 7968.845586 7571.950495 8735.230764 9560.068265 8137.687315 1.038682385 0.912731708 0.905608896 1.050088876 0.776867604 0.979251878 0.93047941 1.073429148 1.174789335 1 12.99040313 -7.266229787 24.9057988 1.018266682 0.943371893 0.219500852 0.092247142 481.9819395 2505867.784 0.012354772 0.014371264 5.42E-08 7.266229787 -0.074894789 VEVGKDQEFTVDTR ddPTM_HeLa_Curcumin_4h_R1 2 VEVGKDQEFTVDTR 14 1 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 124.51 0.0012188 41940000 10127.1 8036.9 8606.3 8896.4 8950.5 10338.3 8398.7 8610.3 9791.5 8024.4 FALSE FALSE TRUE 9325.529349 8731.573824 8925.257049 8859.589054 8843.771133 8194.020043 8634.344918 11235.54083 8717.396947 8303.247303 1.123118343 1.051585423 1.074911625 1.067002912 1.065097884 0.986845236 1.039875678 1.35315021 1.049878033 1 13.01945995 -1 0.010992071 3.77E-10 2.331866101 0.158790292 0.089525129 15468.11214 13.27867541 1198.125011 1653.610908 0.1 1 2.331866101 VEVKEEEESSSNGTASQS(ph)TSPSQPR ddPTM_HeLa_Curcumin_4h_R1 1 VEVKEEEESSSNGTASQSTSPSQPR 25 1 Q92793;Q92793-2;I3L466 Q92793 CREBBP CREB-binding protein 1 0 VEVKEEEESSSNGT(0.044)AS(0.044)QS(0.278)T(0.278)S(0.278)PS(0.077)QPR 78.324 8.00E-05 10827000 926.43 751 1040.5 1093.7 915.14 1203.1 828.9 789.41 1282.2 1279.6 TRUE FALSE FALSE 853.1020879 815.9130936 1079.061845 1089.174559 904.2275532 953.5634983 852.1567031 1030.097475 1141.545868 1324.066005 0.644304804 0.61621784 0.814960766 0.822598387 0.682917279 0.72017822 0.643590803 0.777980457 0.862151784 1 10.37075933 -9.336675233 1.005711396 1.003872559 0.711376329 0.517736734 0.079305066 0.24983136 0.443025987 0.053193071 0.013276541 4.61E-10 9.336675233 -0.29249623 VMS(ph)PENFPTASVEGKEEK ddPTM_HeLa_Curcumin_4h_R1 1 VMSPENFPTASVEGKEEK 18 1 H3BRU9;H3BSP3;H3BTW3;Q3L8U1-2;Q3L8U1-3;Q3L8U1 H3BRU9 CHD9 Chromodomain-helicase-DNA-binding protein 9 1 0 VMS(0.997)PENFPT(0.003)ASVEGKEEK 95.873 0.0046266 15188000 2837.3 2170.5 2534.7 2936.8 1897.4 3002.7 1898.3 891.06 3344.6 2702.6 TRUE FALSE FALSE 2612.724711 2358.108348 2628.638212 2924.6483 1874.774744 2379.906173 1951.561189 1162.740092 2977.705748 2796.515149 0.934278762 0.84323103 0.939969237 1.045818865 0.670396778 0.851025668 0.697854682 0.415781796 1.064791567 1 11.44941443 -4.007348293 0.593279113 0.963742008 2.50E-17 0.750153302 0.095631505 1.533580506 0.298416543 0.015863775 1.079384666 9.83E-05 4.007348293 -0.963742008 down VEVS(ph)EDEPASK ddPTM_HeLa_Curcumin_4h_R1 2 VEVSEDEPASK 11 0 O75683 O75683 SURF6 Surfeit locus protein 6 1 0 VEVS(0.999)EDEPAS(0.001)K;VEVS(1)EDEPASK ; 153.75 0.00046564 42623000 6956.9 6217.4 6956.1 6478 7266.1 5839.1 3473.5 2605.4 5801.5 5353.8 TRUE FALSE FALSE 6406.254024 6754.804352 7213.899185 6451.195752 7179.456503 4628.00484 3570.957062 3399.774466 5165.089965 5539.844151 1.156396073 1.219313065 1.3021845 1.164508527 1.295967234 0.835403436 0.64459522 0.613694966 0.932352937 1 12.43562968 -5.019087424 3.792893194 1.12368983 0.639188744 0.779226364 0.113454981 0.082358597 2.588012949 0.017272786 0.052107222 9.57E-06 5.019087424 -0.484501086 VEVTEFEDIK ddPTM_HeLa_Curcumin_4h_R1 5 VEVTEFEDIK 10 0 Q01105;A0A0C4DFV9;Q01105-3;Q01105-4;A0A087X027;P0DME0;Q01105-2 Q01105;Q01105-2 SET;SETSIP Protein SET;Protein SETSIP 0 0 ;;;; ;;;; 204.79 2.11E-26 62468700 15034.09 12673.69 13669.57 13555.45 14126.33 19550.39 15476.88 15083.31 15371.64 12658.04 FALSE FALSE TRUE 13844.12591 13769.14729 14176.17629 13499.36114 13957.88274 15495.41874 15911.1196 19682.14178 13685.40955 13097.90595 1.056972463 1.051247989 1.082323873 1.030650334 1.065657579 1.183045503 1.214783467 1.502693779 1.044854773 1 13.67704856 -1 0.597338898 1.029099789 30.28223343 0.961200915 0.027885081 20.59736286 0.148121414 0.005388758 788.245115 0.1 1 29.25313364 VEY(ph)T(ph)QMY(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 1 VEYTQMYPGK 10 0 H7C574;U3KQE5;H7C4S2;O60381-2;O60381-3;O60381 H7C574 HBP1 HMG box-containing protein 1 3 0 VEY(1)T(1)QMY(1)PGK 68.735 0.0079883 0 185.3 162.33 226.85 141.13 129.23 0 54.92 0 213.05 121.54 TRUE FALSE FALSE 170.6333095 176.3610819 235.2572606 140.5460415 127.6890167 0 56.46090739 0 189.678948 125.763506 1.356779204 1.402323198 1.870632174 1.11754233 1.015310568 0 0.448945081 0 1.508219309 1 6.974569532 -5.382436167 3.683947922 1.242928655 0.178801765 0.79834935 0.270005142 0.092247677 2.241471108 0.041698363 0.098882396 4.15E-06 5.382436167 -1.06412689 VEYSEEELK ddPTM_HeLa_Curcumin_4h_R1 2 VEYSEEELK 9 0 P12956;P12956-2;B1AHC9 P12956 XRCC6 X-ray repair cross-complementing protein 6 0 0 ; ; 143.73 1.21E-05 6909600 2192.75 2017.97 2239.63 2299.04 2830.5 2714.53 2432.17 1980.82 2358.37 2554.34 FALSE FALSE TRUE 2019.191524 2192.394335 2322.632658 2289.527182 2796.748136 2151.505879 2500.410144 2584.762899 2099.662711 2643.103125 0.763947311 0.82947741 0.878752189 0.866226959 1.05813054 0.814007542 0.946013086 0.977927374 0.794393034 1 11.368017 VFASLPQVER ddPTM_HeLa_Curcumin_4h_R1 1 VFASLPQVER 10 0 D6RD66;O75083;O75083-3 D6RD66 WDR1 WD repeat-containing protein 1 0 0 92.051 0.018861 2330300 1463.3 1481.8 1470.6 1721.1 1513 1541.2 987.54 1173.3 1368.5 1381.8 FALSE FALSE TRUE 1347.478261 1609.880189 1525.10173 1713.978544 1494.958463 1221.537747 1015.247715 1531.033769 1218.378974 1429.817447 0.942412798 1.125934078 1.066640873 1.198739425 1.045558974 0.854331264 0.710054082 1.070789681 0.85212205 1 10.48161525 -5.255300418 24.11663071 1.012795477 0.861557897 0.23781715 0.122092276 326.1152503 1281119.561 0.016395152 0.040623658 5.56E-06 5.255300418 -0.15123758 VFCVEEEDS(ph)ESSLQK ddPTM_HeLa_Curcumin_4h_R1 1 VFCVEEEDSESSLQK 15 0 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 0 VFCVEEEDS(1)ESSLQK 191.01 2.52E-06 14206000 2104.2 1747.9 1800.3 1779.2 1725.9 2601.8 1314.3 873.35 2091.3 1977.3 TRUE FALSE FALSE 1937.65035 1898.980688 1867.020702 1771.838142 1705.31977 2062.157352 1351.175721 1139.630395 1861.889622 2046.011028 0.947038077 0.928138051 0.912517419 0.865996379 0.833485131 1.007891611 0.660395131 0.557001101 0.910009573 1 10.99859821 -3.818853659 0.693804655 0.963236243 1.50E-30 0.737614601 0.070845791 1.619444263 0.357309034 0.011648595 1.410894549 0.000151756 3.818853659 -0.963236243 VFDDES(ph)DEKEDEEYADEK ddPTM_HeLa_Curcumin_4h_R1 1 VFDDESDEKEDEEYADEK 18 1 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 VFDDES(0.877)DEKEDEEY(0.123)ADEK 53.21 0.018146 18071000 2322.6 2239.6 2571.4 2724.3 2658.7 2404.1 2338.8 2563.2 2159.8 2487.2 TRUE FALSE FALSE 2138.763759 2433.181045 2666.698346 2713.027568 2626.996739 1905.46256 2404.420433 3344.70788 1922.875344 2573.630015 0.831030003 0.945427676 1.036162281 1.054163789 1.020735974 0.740379367 0.934252561 1.299607116 0.747145212 1 11.32958895 -6.955548538 7.676828262 0.918556863 0.999716113 0.147925503 0.144876437 0.520114027 76.21651315 0.022882669 0.030059975 1.11E-07 6.955548538 0.08115925 VFDDES(ph)DEKEDEEYADEKGLEAADK ddPTM_HeLa_Curcumin_4h_R1 1 VFDDESDEKEDEEYADEKGLEAADK 25 2 O43719 O43719 HTATSF1 HIV Tat-specific factor 1 1 0 VFDDES(0.967)DEKEDEEY(0.033)ADEKGLEAADK 74.579 0.00012865 61827000 1629.8 1736.7 1870.1 1500.2 1998.1 1499 1932.9 2062.5 1828.5 1636.2 TRUE FALSE FALSE 1500.79961 1886.812609 1939.407551 1493.99257 1974.273963 1188.090503 1987.131972 2691.346755 1627.918125 1693.057828 0.886443207 1.114440734 1.145505794 0.882422647 1.166099545 0.701742423 1.173694093 1.589636639 0.961525411 1 10.72541554 -4.367116124 3.420881067 0.96876644 1.60869213 0.644815961 0.135671121 0.110234457 2.066034842 0.017726217 0.151407345 4.29E-05 4.367116124 0.639925689 VFDEHKEEDLFELSHR ddPTM_HeLa_Curcumin_4h_R1 1 VFDEHKEEDLFELSHR 16 1 Q9NSV4-1;Q9NSV4-7;Q9NSV4-6;Q9NSV4-5;Q9NSV4-4;Q9NSV4;Q9NSV4-2 Q9NSV4-1 DIAPH3 Protein diaphanous homolog 3 0 0 76.156 0.0039474 4778800 5709.1 4585.9 5369.5 5389.7 5498.2 5501.4 4403.5 2406.5 5329.4 4930.5 FALSE FALSE TRUE 5257.218711 4982.284762 5568.498393 5367.398849 5432.637556 4360.347626 4527.050359 3140.230772 4744.778154 5101.834508 1.030456535 0.976567302 1.09146982 1.052052716 1.064840019 0.854662694 0.887337751 0.61551012 0.930014125 1 12.31680039 -4.002009114 0.98140457 1.02227143 0.232646811 0.812143754 0.057922295 0.75381867 0.397836862 0.007493462 0.706771702 9.95E-05 4.002009114 -0.78962462 VFDGIPPPYDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 VFDGIPPPYDKK 12 1 Q8J015;M0QYS1;P40429;Q6NVV1 Q8J015 RPL13a;RPL13A;RPL13AP3 60S ribosomal protein L13a;Putative 60S ribosomal protein L13a protein RPL13AP3 0 1 VFDGIPPPYDK(1)K 127.87 0.00017976 1054200 685.4 1258.1 935.05 842.8 1369.5 2037.2 1342.8 1112.5 1747.6 635.27 FALSE TRUE FALSE 631.1498668 1366.844558 969.7037756 839.3127169 1353.169607 1614.661756 1380.475354 1451.696129 1555.892652 657.3455852 0.960149244 2.079339375 1.475181088 1.276821106 2.058536084 2.456336199 2.100075493 2.208421508 2.366932535 1 9.360508225 -6.2968196 0.526633208 0.941277851 2.362207898 0 0.545774971 0.399207743 0.213067333 0.08871681 0.245149518 5.05E-07 6.2968196 1.420930046 VFDGIPPPYDKK ddPTM_HeLa_Curcumin_4h_R1 2 VFDGIPPPYDKK 12 1 Q8J015;M0QYS1;P40429;Q6NVV1 Q8J015 RPL13a;RPL13A;RPL13AP3 60S ribosomal protein L13a;Putative 60S ribosomal protein L13a protein RPL13AP3 0 0 ; ; 86.911 0.0084032 4421100 3174 2681.85 3059.86 3318.1 2822.99 2883 2456.08 2282.07 3455.8 3244.21 FALSE FALSE TRUE 2922.774551 2913.657164 3173.261103 3304.370581 2789.327688 2285.033302 2524.990995 2977.862638 3076.707386 3356.946056 0.870664736 0.867948759 0.945282126 0.984338302 0.830912276 0.680688121 0.75216907 0.887074915 0.916519758 1 11.71293364 -2.933426744 0.036664914 1.50859421 9.41E-09 0.306254941 0.078676253 420.5048342 1.721095994 24.23180441 51.00047058 0.001165664 2.933426744 -1.508594201 VFDKEGNGTVMGAELR ddPTM_HeLa_Curcumin_4h_R1 1 VFDKEGNGTVMGAELR 16 1 P05976-2;P05976;P08590 P05976-2 MYL1;MYL3 "Myosin light chain 1/3, skeletal muscle isoform;Myosin light chain 3" 0 0 83.292 0.011665 4996600 4321.8 3331.3 3811.6 3899.3 3730.8 5628.2 3627.8 3646.5 4476.7 4119.1 FALSE FALSE TRUE 3979.72497 3619.242728 3952.861249 3883.16573 3686.312647 4460.847877 3729.586304 4758.301064 3985.61721 4262.238418 0.933717117 0.849141313 0.927414391 0.911062533 0.864877157 1.046597454 0.875029958 1.116385476 0.935099546 1 12.05739558 -4.245201239 24.34239285 0.947139491 1.116385663 0.441120791 0.060226564 1797.641949 2694761.754 0.008643767 0.297471174 5.69E-05 4.245201239 0.169246172 VFDLQFSTDS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 VFDLQFSTDSPR 12 0 C9J470;E9PHA2;Q15003;C9JZP1 C9J470 NCAPH Condensin complex subunit 2 1 0 VFDLQFST(0.009)DS(0.991)PR;VFDLQFST(0.001)DS(0.999)PR ; 188.63 6.64E-06 54132000 3752.7 3066.3 2923.7 2883.5 3180.9 6605.2 4872 1961.19 3671.7 2308.3 TRUE FALSE FALSE 3455.669835 3331.337309 3032.054894 2871.568841 3142.969845 5235.207064 5008.695208 2559.147803 3268.923696 2388.513253 1.446786963 1.394732604 1.26943189 1.202241117 1.315868707 2.191826676 2.096992847 1.071439649 1.368601866 1 11.22189717 -9.562553274 0.084119728 7.16E-09 2.277210488 0.131285569 0.35299507 50.80681067 0.982521913 19.29995092 8.511334871 2.74E-10 9.562553274 2.277210481 VFDQQSS(ph)PMVTR ddPTM_HeLa_Curcumin_4h_R1 1 VFDQQSSPMVTR 12 0 O15357;A0A0A0MTP6 O15357 INPPL1 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2" 1 0 VFDQQS(0.112)S(0.888)PMVTR 122.52 0.0038571 7119600 2141.6 1609.9 1664.5 2140.5 1843.4 2329.4 1574.8 806.24 1914.3 2060.1 TRUE FALSE FALSE 1972.0901 1749.052582 1726.187834 2131.643178 1821.418659 1846.256182 1618.98465 1052.058865 1704.306079 2131.688322 0.925130602 0.820501086 0.809774964 0.999978823 0.854448861 0.866100435 0.759484693 0.493533156 0.799509976 1 11.0577808 -3.90039993 0.847819629 0.942290866 4.39E-25 0.658351772 0.080201893 1.377796368 0.48082051 0.011839712 1.397393063 0.000125777 3.90039993 -0.942290866 GRLT(ph)PSPDIIVLS(ph)DNEASSPR ddPTM_HeLa_Curcumin_4h_R1 4 GRLTPSPDIIVLSDNEASSPR 21 1 A0A0U1RRM1;Q8WXI9;A0A0U1RRK3;A0A0U1RR34 A0A0U1RRM1 GATAD2B Transcriptional repressor p66-beta 2 0 GRLT(0.999)PS(0.001)PDIIVLS(0.995)DNEAS(0.005)SPR;GRLT(0.984)PS(0.016)PDIIVLS(0.97)DNEAS(0.016)S(0.013)PR;GRLT(0.991)PS(0.009)PDIIVLS(0.941)DNEAS(0.033)S(0.027)PR;GRLT(0.997)PS(0.244)PDIIVLS(0.482)DNEAS(0.117)S(0.16)PR ;;; 142.96 5.20E-05 44895600 11513.3 9474.8 10159.4 10363.3 10623.7 11833.2 8819.1 3878.99 11060.3 10194.9 TRUE FALSE FALSE 10602.01016 10293.75949 10535.9163 10320.41941 10497.01932 9378.860932 9066.540211 5061.676194 9847.012762 10549.17202 1.005008748 0.975788382 0.998743436 0.978315587 0.995056228 0.889061333 0.859455149 0.479817391 0.933439397 1 13.36484215 -4.003259319 1.194278696 0.997329339 3.11E-20 0.954012435 0.032509071 0.249619139 0.196405339 0.003440114 0.356354287 9.93E-05 4.003259319 -0.997329339 down VFEGNRPTNSIVFTK ddPTM_HeLa_Curcumin_4h_R1 2 VFEGNRPTNSIVFTK 15 1 P06744-2;P06744;A0A2U3TZU2;CON__Q3ZBD7 P06744-2 GPI Glucose-6-phosphate isomerase 0 0 ; ; 119.62 0.00032184 13530500 6066.3 4488.9 4981.3 4949.6 5460.3 6895.1 5596.5 4937.3 5574.8 4262.1 FALSE FALSE TRUE 5586.145954 4876.900514 5165.91136 4929.119867 5395.189489 5464.978536 5753.522728 6442.660041 4963.258387 4410.207658 1.266640119 1.105821062 1.171353315 1.117661627 1.223341372 1.239165808 1.304592249 1.460851856 1.125402424 1 12.10663087 -1 0.026526806 2.33E-13 2.915180486 0.574340059 0.079241085 917.4769489 1.889146144 70.17543045 152.3967434 0.1 1 2.915180486 VFESIGK ddPTM_HeLa_Curcumin_4h_R1 2 VFESIGK 7 0 P35232;C9JZ20;E7ESE2;E9PCW0;C9JW96;P35232-2;D6RBK0 P35232 PHB Prohibitin 0 0 ; ; 120.65 0.009468 5082600 6438.2 5391.4 6115.3 6206 6540.3 7009.8 5019.8 4376.7 7397.2 5565.5 FALSE FALSE TRUE 5928.609676 5857.408592 6341.938398 6180.321216 6462.311194 5555.888463 5160.642078 5711.135682 6585.745667 5758.900711 1.029468986 1.017105327 1.101241142 1.073177248 1.122143186 0.96474809 0.896115828 0.991705877 1.143576873 1 12.49157773 -5.018091192 24.6730431 1.03240477 0.940541116 0.381800485 0.057181519 454.7207038 620157.6395 0.006948798 0.018130473 9.59E-06 5.018091192 -0.091863654 VFGNEIKLEK(ac)PK ddPTM_HeLa_Curcumin_4h_R1 2 VFGNEIKLEKPK 12 2 P19338 P19338 NCL Nucleolin 0 1 ; VFGNEIK(0.001)LEK(0.999)PK;VFGNEIKLEK(1)PK 81.239 0.0095493 3313900 1798.79 1745.18 1090.17 1539.06 1641.68 4003.6 2805.5 3022.6 6017.4 2193.87 FALSE TRUE FALSE 1656.413873 1896.025583 1130.572659 1532.691778 1622.104038 3173.20823 2884.214779 3944.176826 5357.306275 2270.106819 0.729663406 0.835214258 0.498026194 0.675162845 0.714549652 1.397823311 1.270519411 1.737441072 2.359935766 1 11.14854447 -5.218827431 6.016325706 0.81364207 1.455877666 0.111825773 0.517519305 0.089774209 8.70890611 0.027554069 0.070492725 6.04E-06 5.218827431 0.642235596 VFGWEEDEDF ddPTM_HeLa_Curcumin_4h_R1 1 VFGWEEDEDF 10 0 Q9BWD3;Q17RB0;A6ZKI3 Q9BWD3 FAM127B;FAM127C;FAM127A Protein FAM127B;Protein FAM127C;Protein FAM127A 0 0 137.77 0.015514 2244200 1967.5 1359 1572.6 1431.6 1389.9 2265.7 1969.9 1555.6 1857.7 1560.8 FALSE FALSE TRUE 1811.770299 1476.465904 1630.881939 1425.676419 1373.32635 1795.76828 2025.170092 2029.895279 1653.914958 1615.037684 1.121813018 0.914199043 1.009810456 0.882751178 0.850337032 1.111904879 1.25394603 1.256871774 1.024072054 1 10.65735211 -4.901642769 4.001753139 1.017553375 1.254367784 0.624276242 0.083122428 0.141539229 4.196664435 0.0141139 0.04663498 1.25E-05 4.901642769 0.236814409 VFIDQNLS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 1 VFIDQNLSPGK 11 0 F5H452;Q5JSB6;Q5JSB5;Q14186 F5H452 TFDP1 Transcription factor Dp-1 1 0 VFIDQNLS(1)PGK 137.95 0.0016551 35593000 3029.5 2628.8 2946.7 3122.1 3477.1 3497.8 2855.7 1676.2 2416.4 2443.4 TRUE FALSE FALSE 2789.711878 2856.021758 3055.907294 3109.181577 3435.637853 2772.316852 2935.823256 2187.265664 2151.326966 2528.307968 1.10339085 1.129617829 1.208676843 1.229747965 1.35886842 1.096510744 1.161181032 0.865110458 0.850895932 1 11.30395649 -8.123928788 0.852658416 1.016233749 1.160370835 0.262147302 0.129568885 0.623781287 0.974593608 0.039264792 0.027227032 7.52E-09 8.123928788 0.144137086 VFIGNLNTLVVK ddPTM_HeLa_Curcumin_4h_R1 1 VFIGNLNTLVVK 12 0 P07910;P07910-2;G3V2Q1;G3V4C1;P07910-4;B2R5W2;B4DY08;G3V4W0;P07910-3;G3V576;G3V555;G3V575;B7ZW38;A0A0G2JPF8;P0DMR1;B4DSU6;G3V251;G3V3K6;G3V5X6;G3V4M8;G3V2H6;A0A0G2JNQ3;O60812;B2RXH8 P07910;A0A0G2JNQ3 HNRNPC;HNRNPCL3;HNRNPCL4;HNRNPCL1;HNRNPCL2 Heterogeneous nuclear ribonucleoproteins C1/C2;Heterogeneous nuclear ribonucleoprotein C-like 3;Heterogeneous nuclear ribonucleoprotein C-like 4;Heterogeneous nuclear ribonucleoprotein C-like 1;Heterogeneous nuclear ribonucleoprotein C-like 2 0 0 188.28 7.07E-45 0 384.82 284.31 322.77 166.15 323.42 635.43 393.33 405.15 376.55 162.36 FALSE FALSE TRUE 354.3610909 308.8844895 334.7321401 165.4625153 319.5634277 503.6346552 404.3657812 528.6783699 335.2434071 168.0019979 2.109267124 1.838576287 1.99242952 0.984884212 1.902140639 2.997789678 2.40691055 3.146857636 1.99547274 1 7.39233458 -1 0.12740714 0.875282681 7.430715049 0.42086826 0.512793522 53.43219113 0.461529684 1.905263045 62.96628205 0.1 1 6.555432368 VFLQGPAPVGT(ph)PSFNR ddPTM_HeLa_Curcumin_4h_R1 1 VFLQGPAPVGTPSFNR 16 0 Q8IWZ3-6;Q8IWZ3;Q8IWZ3-4;H0Y785;H0Y472;H0Y4P6;H7C0V5 Q8IWZ3-6 ANKHD1;ANKHD1-EIF4EBP3 Ankyrin repeat and KH domain-containing protein 1 1 0 VFLQGPAPVGT(0.966)PS(0.034)FNR 91.592 0.014761 18614000 1776.5 1315.1 1525.2 1793.9 1731.7 3168.8 2603.9 2055.6 1927 1467.7 TRUE FALSE FALSE 1635.88815 1428.771384 1581.725254 1786.477317 1711.050609 2511.55516 2676.958426 2682.342977 1715.612921 1518.702466 1.077161714 0.940784266 1.041497785 1.176318178 1.126652947 1.65375063 1.762661539 1.766207034 1.129657033 1 10.56862354 -5.25440254 2.101779639 1.03718331 1.77847623 0.956120051 0.064762839 0.040616738 0.344511841 0.008914482 0.027476677 5.57E-06 5.25440254 0.74129292 VFPEPTES(ph)GDEGEELGLPLLSTR ddPTM_HeLa_Curcumin_4h_R1 2 VFPEPTESGDEGEELGLPLLSTR 23 0 Q9BUR4;E9PMG4 Q9BUR4 WRAP53 Telomerase Cajal body protein 1 1 0 VFPEPTES(1)GDEGEELGLPLLSTR;VFPEPT(0.019)ES(0.981)GDEGEELGLPLLSTR ; 156.8 3.03E-07 64407000 7144.2 5310.6 6285.6 5960 6303.9 7613.4 6723.6 6251 7611.9 6210.1 TRUE FALSE FALSE 6578.729031 5769.6246 6518.549865 5935.339099 6228.73011 6034.295019 6912.24612 8156.901124 6776.893614 6425.900513 1.023783206 0.897870203 1.014418112 0.923658729 0.9693163 0.93905827 1.075685207 1.269378682 1.054621621 1 12.64968293 -4.341124171 2.884374037 0.990612177 1.294430593 0.773358449 0.047642263 0.116289847 1.464937434 0.006433616 0.0741706 4.56E-05 4.341124171 0.303818416 VFSGLVS(ph)TGLK ddPTM_HeLa_Curcumin_4h_R1 2 VFSGLVSTGLK 11 0 P13639 P13639 EEF2 Elongation factor 2 1 0 VFSGLVS(0.773)T(0.227)GLK;VFS(0.02)GLVS(0.951)T(0.029)GLK ; 133.88 0.0022644 35321000 4533.9 3072.6 4045.5 3891.5 3802.6 4384.7 3449.9 3115.2 4404.7 3575.6 TRUE FALSE FALSE 4175.037031 3338.181853 4195.429789 3875.398004 3757.256479 3475.263794 3546.694909 4065.010139 3921.51543 3699.851834 1.128433575 0.902247442 1.133945352 1.047446811 1.01551539 0.939298099 0.958604579 1.098695386 1.059911479 1 11.85325178 -5.661184599 3.955879116 1.054177318 0.992696712 0.067252746 0.073005761 0.386228521 11.29407162 0.011310923 0.023304625 2.18E-06 5.661184599 -0.061480606 VFSGLVSTGLK ddPTM_HeLa_Curcumin_4h_R1 2 VFSGLVSTGLK 11 0 P13639 P13639 EEF2 Elongation factor 2 0 0 ; ; 198.72 1.11E-16 3244400 2850.6 1960.36 2365.2 2565.83 2624.44 2357.59 2068.38 2310.31 2358.64 2750.4 FALSE FALSE TRUE 2624.972002 2129.804783 2452.856393 2555.213275 2593.145267 1868.599258 2126.413176 3014.712884 2099.903093 2845.976195 0.922345031 0.7483565 0.861868204 0.897833678 0.911161967 0.656575857 0.747164779 1.059289564 0.737849844 1 11.47470788 -7.661031826 1.975899597 0.973614071 0.835693465 0 0.129108115 0.305198499 2.477995576 0.020728389 0.02110651 2.18E-08 7.661031826 -0.137920606 VFTTVGSAEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 VFTTVGSAEKR 11 1 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 1 VFTTVGSAEK(1)R 104.43 0.0021634 10115000 1854.2 1633.9 1444.1 1469.8 1568.5 601.87 1082.8 1282.7 1854.8 1435.6 FALSE TRUE FALSE 1707.438113 1775.127035 1497.619616 1463.718357 1549.796662 477.0353775 1113.180454 1673.789325 1651.33308 1485.486993 1.149413035 1.194979858 1.008167438 0.985345792 1.043291977 0.321130632 0.749370717 1.126761347 1.111644254 1 10.53672026 -5.479680328 24.99747641 1.069734058 0.725464971 0.397356082 0.190961489 346.8659778 200719.3551 0.026611817 0.059501552 3.31E-06 5.479680328 -0.344269087 VGALDVPASQFLGSAT(ph)SPGPR ddPTM_HeLa_Curcumin_4h_R1 2 VGALDVPASQFLGSATSPGPR 21 0 H3BMQ0;A0A2R8YDR3;A0A2R8Y7X5;P49815-3;P49815-5;A0A2R8Y6C9;A0A2R8Y5F1;P49815;A0A2R8YGD6;A0A2R8Y7C8;A0A2R8YDZ2;A0A2R8YGU4;X5D2U8;P49815-2;P49815-6;P49815-7;P49815-4 H3BMQ0 TSC2 Tuberin 1 0 VGALDVPAS(0.002)QFLGS(0.004)AT(0.497)S(0.497)PGPR;VGALDVPAS(0.004)QFLGS(0.008)AT(0.494)S(0.494)PGPR ; 135.21 9.07E-05 31397000 5036.6 3512.2 4405.9 4370.6 3577.2 4558.9 2608.2 2308.1 3931.9 3237.7 TRUE FALSE FALSE 4637.947795 3815.778918 4569.18653 4352.515615 3534.544226 3613.332751 2681.379072 3011.829065 3500.580407 3350.209834 1.384375315 1.138967141 1.36385085 1.299177016 1.055021745 1.078539235 0.800361531 0.898997142 1.044883927 1 11.71003574 -5.056003833 1.71326501 1.201878172 0.843656563 0.510499051 0.12843202 0.289998285 1.582423704 0.023751184 0.101901872 8.79E-06 5.056003833 -0.358221609 VGANFY(ph)S(ph)S(ph)VKQQDYS(ph)AS(ph)VWLRRK ddPTM_HeLa_Curcumin_4h_R1 1 VGANFYSSVKQQDYSASVWLRRK 23 3 J3KP61;F5GXZ8;Q8N7P1 J3KP61 PLD5 Inactive phospholipase D5 5 0 VGANFY(0.995)S(0.996)S(0.996)VKQQDY(0.492)S(0.555)AS(0.966)VWLRRK 41.53 0.0083768 0 305 319.53 491.74 418.82 497.66 537.76 366.39 301.66 522.45 374.39 TRUE FALSE FALSE 280.8589282 347.1487494 509.964317 417.0870338 491.7257295 426.2225142 376.6699173 393.6347453 465.1385421 387.4000246 0.724984281 0.896098935 1.316376573 1.076631408 1.269297104 1.100212925 0.972302254 1.016093754 1.200667301 1 8.597680235 -6.902603131 9.327289568 0.867038756 1.121148894 0.136134293 0.156483173 0.2089809 18.2763529 0.022672502 0.029817804 1.25E-07 6.902603131 0.254110138 VGDDVEFEVSSDRR ddPTM_HeLa_Curcumin_4h_R1 2 VGDDVEFEVSSDRR 14 1 O75534-2;O75534;O75534-3;O75534-4;E9PLD4 O75534-2 CSDE1 Cold shock domain-containing protein E1 0 0 ; ; 202.61 8.42E-09 95731000 5115 4436.2 4195.7 3989 4774.4 6398.2 4140.1 4182.9 5242.1 4736.7 FALSE FALSE TRUE 4710.142353 4819.645361 4351.196333 3972.494575 4717.468398 5071.141197 4256.260063 5458.246954 4667.054745 4901.299972 0.960998588 0.983340213 0.887763727 0.810498153 0.962493303 1.034652281 0.868394117 1.113632503 0.952207531 1 12.25894873 -4.236299709 23.91706524 0.960302463 1.113632848 0.348175436 0.066223627 4279.501984 4071267.155 0.009497867 0.840594566 5.80E-05 4.236299709 0.153330385 VGDGDLS(ph)AEEIPENEVSLRR ddPTM_HeLa_Curcumin_4h_R1 1 VGDGDLSAEEIPENEVSLRR 20 1 Q14684-2;Q14684 Q14684-2 RRP1B Ribosomal RNA processing protein 1 homolog B 1 0 VGDGDLS(1)AEEIPENEVSLRR 109.12 0.00012511 148810000 2647.8 1672.5 1747.6 2014.3 1834.9 2213.6 1227.6 910.17 2732.2 2120.2 TRUE FALSE FALSE 2438.223836 1817.063447 1812.367593 2005.96536 1813.020016 1754.474408 1262.043152 1187.676643 2432.484496 2193.876792 1.111376831 0.82824316 0.826102724 0.914347318 0.826400107 0.799714193 0.575257078 0.541359773 1.108760758 1 11.09926679 -4.312858529 0.376423483 1.054727475 0.126306769 0.817715058 0.078341072 1.821939879 0.182081907 0.027684153 0.758938314 4.87E-05 4.312858529 -0.928420706 VGDK(ac)VLLPEYGGTK ddPTM_HeLa_Curcumin_4h_R1 1 VGDKVLLPEYGGTK 14 1 P61604;B8ZZL8;B8ZZ54 P61604 HSPE1 "10 kDa heat shock protein, mitochondrial" 0 1 VGDK(1)VLLPEYGGTK 168.89 4.94E-05 779330 692.44 482.98 643.54 707.85 841.91 1176.4 815.85 806.54 753.75 637.68 FALSE TRUE FALSE 637.6326433 524.7266391 667.3901585 704.9211043 831.8707731 932.4013792 838.7405553 1052.450333 671.0655108 659.8393325 0.966345308 0.79523395 1.011443431 1.068322347 1.260717166 1.413073355 1.271128461 1.595009999 1.017013503 1 9.365970968 -5.657046057 1.496753823 0.967570649 1.428748918 0.833506266 0.0929374 0.113405547 0.506773672 0.013743716 0.036523622 2.20E-06 5.657046057 0.461178269 VGDPPQPLPEEPMEVQGAERAS(ph)PEPQR ddPTM_HeLa_Curcumin_4h_R1 3 VGDPPQPLPEEPMEVQGAERASPEPQR 27 1 P46379-3;P46379;P46379-2;P46379-5;A0A0G2JK23;A0A024RCR6;A0A0G2JL47;H0Y710 P46379-3 BAG6;BAT3 Large proline-rich protein BAG6 1 0 VGDPPQPLPEEPMEVQGAERAS(1)PEPQR;VGDPPQPLPEEPMEVQGAERAS(1)PEPQR;VGDPPQPLPEEPMEVQGAERAS(1)PEPQR ;; 96.783 1.45E-06 118438000 4982.1 4522.5 5057.3 4464.3 5271.5 4977.1 4094.2 4168.5 4110.3 3632.4 TRUE FALSE FALSE 4587.761528 4913.404748 5244.727987 4445.827909 5208.640805 3944.793357 4209.072233 5439.456461 3659.410373 3758.62563 1.2205955 1.307234408 1.395384511 1.182833394 1.385783347 1.049530798 1.119843434 1.447192936 0.973603315 1 11.87598951 -8.758396081 0.76718486 1.006080308 1.25922624 0.450444727 0.120828803 0.486436567 0.557958941 0.066367689 0.025489427 1.74E-09 8.758396081 0.253145933 EAALPPVS(ph)PLK ddPTM_HeLa_Curcumin_4h_R1 4 EAALPPVSPLK 11 0 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 0 EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK;EAALPPVS(1)PLK ;;; 120.84 0.0040901 1248340000 46479.2 36148.6 48564.4 37543.4 52660.7 53914.7 55361.4 61981.4 35022.6 34280.3 TRUE FALSE FALSE 42800.32228 39273.12391 50364.23939 37388.05536 52032.75555 42732.18348 56914.69189 80879.24353 31180.7084 35471.53787 1.206610281 1.107172856 1.419849333 1.054029726 1.466887501 1.204689338 1.604517179 2.280116634 0.87903458 1 15.11437426 -1 0.628265225 1.118088636 89.26138188 0.827103682 0.15960244 46.80053372 0.302782886 0.024644835 5721.506265 0.1 1 88.14329324 up VGDSTPVSEKPVSAAVDANASES(ph)P ddPTM_HeLa_Curcumin_4h_R1 2 VGDSTPVSEKPVSAAVDANASESP 24 1 Q9H8Y8-2;Q9H8Y8;Q9H8Y8-3 Q9H8Y8-2 GORASP2 Golgi reassembly-stacking protein 2 1 0 VGDSTPVSEKPVSAAVDANAS(0.003)ES(0.997)P;VGDSTPVSEKPVSAAVDANAS(0.004)ES(0.996)P ; 102.72 2.41E-06 204935000 10204.6 8569.5 8480.5 8736.6 9418.2 10370.3 6621.7 5508.1 10216.1 8752.2 TRUE FALSE FALSE 9396.895142 9310.209395 8794.79479 8700.450264 9305.894116 8219.382883 6807.487081 7187.494334 9095.419389 9056.338299 1.037604254 1.028032422 0.971120391 0.960702878 1.027555929 0.907583464 0.751682066 0.79364243 1.00431533 1 13.14471214 -4.968738571 2.909035899 1.011402768 0.77134988 0.920532098 0.026940985 0.050339008 0.858691414 0.004262569 0.014758056 1.07E-05 4.968738571 -0.240052888 VGDTEKPEPERS(ph)PPNR ddPTM_HeLa_Curcumin_4h_R1 1 VGDTEKPEPERSPPNR 16 2 Q9NZ63 Q9NZ63 C9orf78 Uncharacterized protein C9orf78 1 0 VGDTEKPEPERS(1)PPNR 78.505 0.0039654 527770000 3165.3 2481.9 2757.7 2472.6 2565.1 2997.4 2347.4 2153 3131.9 2483.2 TRUE FALSE FALSE 2914.763165 2696.424377 2859.902788 2462.369036 2534.512858 2375.705452 2413.261726 2809.439789 2788.338406 2569.491015 1.134373753 1.049400197 1.113023074 0.95831004 0.986387126 0.924582121 0.939198352 1.093383776 1.085171495 1 11.32726689 -6.250071384 24.83490368 1.067168126 0.975319543 0.428534193 0.054772856 628.5740047 1373203.165 0.009781943 0.016115503 5.62E-07 6.250071384 -0.091848583 VGEDEDGS(ph)DEEVVHNEDIHFEPIVSLPEVEVK ddPTM_HeLa_Curcumin_4h_R1 4 VGEDEDGSDEEVVHNEDIHFEPIVSLPEVEVK 32 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 VGEDEDGS(0.978)DEEVVHNEDIHFEPIVS(0.022)LPEVEVK;VGEDEDGS(1)DEEVVHNEDIHFEPIVSLPEVEVK;VGEDEDGS(0.998)DEEVVHNEDIHFEPIVS(0.002)LPEVEVK;VGEDEDGS(0.999)DEEVVHNEDIHFEPIVS(0.001)LPEVEVK ;;; 69.241 1.94E-05 580744800 16239.3 13757.83 13096.77 14464.8 14049.7 16243.3 11364.1 7202.98 16398.6 14554.36 TRUE FALSE FALSE 14953.94227 14946.99552 13582.14782 14404.94849 13882.1665 12874.25648 11682.94606 9399.135444 14599.71461 15060.12293 0.992949549 0.992488281 0.901861684 0.956496076 0.92178308 0.85485733 0.775753699 0.624107485 0.969428648 1 13.87844593 -3.508184096 0.506803831 0.996375984 2.53E-17 0.954145775 0.024346136 0.96855418 0.096813676 0.004515034 0.680699371 0.000310324 3.508184096 -0.996375984 VGEDEDGSDEEVVHNEDIHFEPIVS(ph)LPEVEVK ddPTM_HeLa_Curcumin_4h_R1 1 VGEDEDGSDEEVVHNEDIHFEPIVSLPEVEVK 32 0 P49792 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 VGEDEDGS(0.401)DEEVVHNEDIHFEPIVS(0.599)LPEVEVK 42.894 0.010066 9833600 1738.9 1541.5 1535.6 1607.4 1524.2 1664.4 1093.6 780.43 1955.7 1662.8 TRUE FALSE FALSE 1601.26423 1674.740391 1592.510687 1600.749005 1506.02491 1319.184678 1124.283473 1018.379514 1741.164603 1720.582176 0.930652573 0.973356817 0.925565026 0.930353125 0.875299612 0.766708325 0.653432012 0.591880776 1.011962478 1 10.74868108 -4.875935962 0.818377745 0.96743313 0.511668576 0.972156817 0.023176966 0.150347776 0.121489409 0.004362439 0.051091627 1.33E-05 4.875935962 -0.455764555 VGEEEHVY(ph)SFPNK ddPTM_HeLa_Curcumin_4h_R1 1 VGEEEHVYSFPNK 13 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-3;A0A1B0GU60;F5H836 A0A1B0GTU4 PXN Paxillin 1 0 VGEEEHVY(0.989)S(0.011)FPNK 177.04 0.00095533 45644000 9420.8 8900.9 9281 8130.5 10496 15989 10410 3579.5 10272 8205.2 TRUE FALSE FALSE 8675.133739 9670.254134 9624.962024 8096.858145 10370.84206 12672.70117 10702.07658 4670.873072 9145.187299 8490.330089 1.021766368 1.138972694 1.133638142 0.953656461 1.221488675 1.492604061 1.260501826 0.550140339 1.07712977 1 13.05160493 -7.305116157 5.115707769 1.009687123 1.127600667 0.013326366 0.229853323 0.509703202 32.44118026 0.038669064 0.0445317 4.95E-08 7.305116157 0.117913544 VGEEEHVYS(ph)FPNK ddPTM_HeLa_Curcumin_4h_R1 1 VGEEEHVYSFPNK 13 0 A0A1B0GTU4;F5GZ78;P49023;P49023-2;P49023-3;A0A1B0GU60;F5H836 A0A1B0GTU4 PXN Paxillin 1 0 VGEEEHVY(0.156)S(0.844)FPNK 134.04 0.0013818 11337000 1710.4 1875.7 1770.8 1870.8 1962 2688.7 1500.2 860.08 1777.2 1480.6 TRUE FALSE FALSE 1575.020035 2037.82715 1836.427406 1863.059125 1938.604431 2131.033312 1542.291574 1122.314433 1582.245606 1532.05074 1.028046914 1.330130326 1.198672706 1.216055759 1.265365683 1.390967842 1.006684397 0.73255696 1.032763188 1 10.58124836 -7.477721769 21.42182069 1.012373363 1.173472554 0.120880782 0.174794816 115.2658453 54681.36026 0.030390345 0.03453398 3.33E-08 7.477721769 0.161099191 VGEFCHNR ddPTM_HeLa_Curcumin_4h_R1 2 VGEFCHNR 8 0 P22314;P22314-2;Q5JRR9;Q5JRS0;Q5JRS2 P22314 UBA1 Ubiquitin-like modifier-activating enzyme 1 0 0 ; ; 101.6 0.0033948 3087300 4454.9 3195.8 3988.1 3841.3 3477.4 4378 3395.4 3334 3795.4 4048.9 FALSE FALSE TRUE 4102.289964 3472.030712 4135.902494 3825.405718 3435.934276 3469.95345 3490.665786 4350.521252 3379.054116 4189.598974 0.979160533 0.828726266 0.987183384 0.913072049 0.82011054 0.828230452 0.833174203 1.038409948 0.806534023 1 12.03259644 -7.39049221 6.728071586 0.990852757 0.889690741 0 0.090434846 0.214739365 10.87437628 0.011565871 0.013176012 4.07E-08 7.39049221 -0.101162016 VGEFSGANK ddPTM_HeLa_Curcumin_4h_R1 2 VGEFSGANK 9 0 P10599-2;P10599 P10599-2 TXN Thioredoxin 0 0 ; ; 154.49 5.95E-08 51543000 12812.3 9017.6 12520.5 10816.9 13063.8 13644.3 11625.1 11440.6 11134 9099.5 FALSE FALSE TRUE 11798.19294 9797.041162 12984.52074 10772.14253 12908.02272 10814.31838 11951.26902 14928.78627 9912.628056 9415.706948 1.25303315 1.040499796 1.379027705 1.144060939 1.370903193 1.148540246 1.269290674 1.585519426 1.052775762 1 13.2008537 -1.000028135 0.030912262 6.59E-09 3.069871082 0.485169686 0.125196655 742.2670416 1.776644815 55.89274665 137.8244835 0.099993522 1.000028135 3.069871075 VGEFSGANK(ac)EK ddPTM_HeLa_Curcumin_4h_R1 1 VGEFSGANKEK 11 1 P10599-2;P10599 P10599-2 TXN Thioredoxin 0 1 VGEFSGANK(1)EK 134.57 0.0005017 6791200 2434.6 3057.6 1786.4 1961.9 3396.1 5936.9 3881.8 3831.1 6299 2178.1 FALSE TRUE FALSE 2241.898841 3321.88532 1852.605555 1953.782178 3355.603726 4705.520017 3990.712861 4999.184754 5608.015459 2253.788813 0.994724452 1.473911531 0.821996074 0.866887867 1.488872296 2.087826504 1.770668502 2.218124753 2.48826129 1 11.13813662 -5.500750264 3.276253365 1.015253568 1.995454203 0.217659491 0.506049229 0.06702238 1.474192258 0.0276043 0.063143681 3.16E-06 5.500750264 0.980200635 VGEVIVTK ddPTM_HeLa_Curcumin_4h_R1 2 VGEVIVTK 8 0 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 ; ; 114.89 0.0037834 24205000 9814.2 10295.7 10891.4 11956.6 13045.7 17219.8 12937.6 11689.9 10800.7 8274.5 FALSE FALSE TRUE 9037.395714 11185.61443 11295.04487 11907.12676 12890.13855 13648.21937 13300.59424 15254.0967 9615.890232 8562.038259 1.055519193 1.306419581 1.319200466 1.390688338 1.505498826 1.594038588 1.553437842 1.781596418 1.12308424 1 13.06373857 -6.218589328 0.487739918 0.989821814 1.739173089 0.913502663 0.070519664 0.162148283 0.072120352 0.017070761 0.052110054 6.05E-07 6.218589328 0.749351275 VGEVIVTKDDAMLLK ddPTM_HeLa_Curcumin_4h_R1 1 VGEVIVTKDDAMLLK 15 1 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 78.985 0.014361 12299000 1357.1 1180.6 1280.9 1333.6 1185.4 2540.7 1550.6 1497.3 1718.6 1606.2 FALSE FALSE TRUE 1249.684103 1282.645803 1328.371281 1328.081917 1171.264879 2013.73018 1594.105663 1953.819877 1530.07388 1662.01533 0.75190889 0.771741259 0.799253326 0.799079222 0.704725677 1.211619498 0.959140168 1.175572717 0.920613578 1 10.69871797 -5.256974786 24.99931994 0.84863139 1.099813732 0.621854487 0.103437291 264.4690499 1480876.912 0.017796018 0.043730616 5.53E-06 5.256974786 0.251182342 VGGPLAVLGPSRS(ph)SEDLAGPLPSSVSSSSTTSSKPK ddPTM_HeLa_Curcumin_4h_R1 2 VGGPLAVLGPSRSSEDLAGPLPSSVSSSSTTSSKPK 36 2 Q9NRF2-3;Q9NRF2-2;Q9NRF2 Q9NRF2-3 SH2B1 SH2B adapter protein 1 1 0 VGGPLAVLGPS(0.141)RS(0.429)S(0.429)EDLAGPLPSSVSSSSTTSSKPK;VGGPLAVLGPS(0.122)RS(0.437)S(0.437)EDLAGPLPS(0.003)S(0.001)VSSSSTTSSKPK ; 118.15 6.93E-19 160412000 1946.89 1723.58 1707.4 2070.9 1465.16 2293.65 1624.83 752.02 2588.4 2190.75 TRUE FALSE FALSE 1792.791602 1872.558575 1770.677746 2062.331165 1447.688924 1817.921135 1670.418357 981.3074361 2304.458996 2266.878399 0.790863596 0.82605162 0.781108394 0.909767002 0.638626635 0.801949119 0.736880442 0.432889314 1.016578126 1 11.14649129 -3.007868899 0.107526153 1.117054172 4.55E-19 0.649669939 0.096251652 34.84562889 0.424951174 0.74770215 5.79109968 0.000982044 3.007868899 -1.117054172 VGGS(ph)DEEASGIPSR ddPTM_HeLa_Curcumin_4h_R1 4 VGGSDEEASGIPSR 14 0 H7C446;A8MV53;A0A0A6YYI3;A0A0B4J1V8;Q9NQ55-2;Q9NQ55;Q9NQ55-3 H7C446 PPAN;PPAN-P2RY11 Suppressor of SWI4 1 homolog 1 0 VGGS(0.999)DEEAS(0.001)GIPSR;VGGS(1)DEEASGIPSR;VGGS(1)DEEASGIPSR;VGGS(0.986)DEEAS(0.014)GIPSR ;;; 225.21 3.05E-20 2313876000 5693.52 4788.79 5104.87 5979.12 6249.51 5981.45 4101.48 2720.97 6549.66 5340.21 TRUE FALSE FALSE 5242.871884 5202.711669 5294.060973 5954.379986 6174.988675 4740.829845 4216.55649 3550.581227 5831.178684 5525.7819 0.948801813 0.941534024 0.958065495 1.077563337 1.117486862 0.857947333 0.763069655 0.642548202 1.055267615 1 12.43196291 -4.797529467 2.364015533 0.987080428 0.671510453 0.789587103 0.063905492 0.10531002 1.135936129 0.009095517 0.043345229 1.59E-05 4.797529467 -0.315569975 VGGS(ph)SVDLHR ddPTM_HeLa_Curcumin_4h_R1 3 VGGSSVDLHR 10 0 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12 O60716 CTNND1 Catenin delta-1 1 0 VGGS(0.866)S(0.134)VDLHR;VGGS(0.955)S(0.045)VDLHR;VGGS(0.804)S(0.196)VDLHR ;; 116.71 0.0024266 193841000 16942.2 20089.5 15810.8 17637.5 20039.3 35189 28840.1 23813.8 25799.3 18905.4 TRUE FALSE FALSE 15601.20699 21825.94686 16396.76216 17564.5207 19800.34444 27890.40474 29649.27559 31074.51799 22969.18134 19562.36124 0.797511446 1.115711268 0.838179091 0.897873241 1.012165361 1.425717703 1.515628672 1.58848503 1.174151783 1 14.2557929 -5.234915828 2.350229854 0.913377192 1.551431416 0.809826986 0.117700905 0.070047508 0.749326489 0.014268618 0.042555167 5.82E-06 5.234915828 0.638054225 VGGSDEEAS(ph)GIPSR ddPTM_HeLa_Curcumin_4h_R1 1 VGGSDEEASGIPSR 14 0 H7C446;A8MV53;A0A0A6YYI3;A0A0B4J1V8;Q9NQ55-2;Q9NQ55;Q9NQ55-3 H7C446 PPAN;PPAN-P2RY11 Suppressor of SWI4 1 homolog 1 0 VGGS(0.405)DEEAS(0.465)GIPS(0.13)R 104.7 0.0037778 10493000 940.93 740.21 868.12 630.73 729.72 1213.8 612.29 682.2 970.31 745.16 TRUE FALSE FALSE 866.4543976 804.1904541 900.2932909 628.1202064 721.0185656 962.0441977 629.4692095 890.1996395 863.8694206 771.0542545 1.123726888 1.042975185 1.167613414 0.814625174 0.935107434 1.247699746 0.816374731 1.1545227 1.120374365 1 9.590688567 VGGSGVNVNAK ddPTM_HeLa_Curcumin_4h_R1 2 VGGSGVNVNAK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 163.64 4.16E-08 7592400 2653.2 2371 2537.1 2544.9 2489.6 2969.8 2235.3 2782 2959.2 2137.1 FALSE FALSE TRUE 2443.19642 2575.938675 2631.127158 2534.369878 2459.913146 2353.830003 2298.016502 3630.218993 2634.583164 2211.364066 1.10483681 1.164864128 1.189820889 1.14606632 1.112396273 1.064424461 1.039185061 1.641619781 1.191383727 1 11.11072085 -4.258992502 24.87931699 1.078581764 1.641619993 0.837520841 0.068452627 60.19678468 612027.3026 0.010343948 0.092925478 5.51E-05 4.258992502 0.56303823 VGGSS(ph)VDLHR ddPTM_HeLa_Curcumin_4h_R1 3 VGGSSVDLHR 10 0 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62;O60716-18;O60716-10;O60716-9;O60716-17;O60716-11;O60716-13;O60716-19;O60716-21;O60716-20;O60716-22;O60716-23;O60716-14;O60716-24;O60716-16;O60716-15;O60716-12 O60716 CTNND1 Catenin delta-1 1 0 VGGS(0.182)S(0.818)VDLHR;VGGS(0.224)S(0.776)VDLHR;VGGS(0.412)S(0.588)VDLHR ;; 173.72 0.00020147 142600000 13443.8 12997.7 12345.3 12823.7 13844.4 19868.1 13610.9 14149.9 17014.2 11728.5 TRUE FALSE FALSE 12379.70904 14121.16327 12802.82768 12770.63893 13679.31457 15747.2321 13992.78522 18464.13937 15147.78483 12136.0645 1.020076075 1.163570222 1.054940642 1.05228832 1.127162316 1.297556724 1.152991995 1.521427261 1.248162848 1 13.56701304 -1 0.365862719 1.008488734 6.913426617 0.523280008 0.10382863 16.80269369 0.207343984 0.018123938 70.34890258 0.1 1 5.904937883 VGGTSDVEVNEK ddPTM_HeLa_Curcumin_4h_R1 4 VGGTSDVEVNEK 12 0 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 ;;; ;;; 251.64 5.48E-63 52306100 9756.8 9715.7 10386.9 11399.1 11556.6 16174.4 11682.7 10937.5 10889.1 7897.3 FALSE FALSE TRUE 8984.538985 10555.48182 10771.84765 11351.93354 11418.79509 12819.64712 12010.48512 14272.2934 9694.592973 8171.730587 1.099465883 1.291707026 1.318184384 1.389171293 1.397353348 1.568779952 1.46976029 1.74654478 1.18635739 1 12.99642593 -5.793660844 0.320909404 0.97310554 1.826843181 0.833822189 0.085468524 0.47206172 0.074980832 0.031891749 0.146594182 1.61E-06 5.793660844 0.853737642 VGGTSDVEVNEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VGGTSDVEVNEKK 13 1 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 1 ; VGGTSDVEVNEK(1)K;VGGTSDVEVNEK(1)K 253.76 7.96E-63 11279700 2569.4 4058.9 2988.2 3094.7 6354.2 10622.9 6916.9 6236.3 8381.9 2768.8 FALSE TRUE FALSE 2366.029279 4409.73323 3098.945321 3081.894951 6278.430315 8419.590795 7110.969598 8137.719162 7462.42654 2865.015594 0.825834695 1.539165525 1.08165042 1.075699189 2.191412266 2.938759151 2.482000312 2.840375172 2.604672225 1 11.48432728 -5.662625287 2.820976208 0.983361994 2.722536527 0.507517956 0.557413503 0.049122953 0.788055034 0.03427168 0.073854763 2.17E-06 5.662625287 1.739174533 VGGTSDVEVNEKK ddPTM_HeLa_Curcumin_4h_R1 1 VGGTSDVEVNEKK 13 1 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 141.37 0.00014474 10445000 1894 1711 1420.9 2123.9 2288.1 3287.1 1865.5 1978.9 2241.2 1528 FALSE FALSE TRUE 1744.087901 1858.891216 1473.559804 2115.111865 2260.815902 2605.318407 1917.840909 2582.2575 1995.345967 1581.097886 1.103086606 1.175696478 0.931985184 1.337748841 1.429902552 1.647790709 1.212980503 1.633205333 1.262000275 1 10.62671097 -6.064681031 3.578971996 1.053792643 1.469302247 0.611178984 0.143811179 0.093128853 2.347298339 0.01810623 0.031809258 8.62E-07 6.064681031 0.415509604 VGIDT(ph)PDIDIHGPEGK ddPTM_HeLa_Curcumin_4h_R1 5 VGIDTPDIDIHGPEGK 16 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VGIDT(1)PDIDIHGPEGK;VGIDT(1)PDIDIHGPEGK;VGIDT(1)PDIDIHGPEGK;VGIDT(1)PDIDIHGPEGK;VGIDT(1)PDIDIHGPEGK ;;;; 166.57 0.00017793 405934800 17202.8 11821.8 17207.7 17735 15785 18439.2 17347.5 15186.5 16121.1 11605.7 TRUE FALSE FALSE 15841.18023 12843.62372 17845.4325 17661.61727 15596.77418 14614.70207 17834.22416 19816.79394 14352.65566 12008.99721 1.319109327 1.0695001 1.486005216 1.470698757 1.298757416 1.216979387 1.485071888 1.650162257 1.195158547 1 13.55182807 -11.83529143 0.082518609 1.92E-13 1.818300412 0.460655792 0.142843696 62.84289048 0.573893684 13.86591722 2.68544131 1.46E-12 11.83529143 1.818300412 VGINYQPPTVVPGGDLAK ddPTM_HeLa_Curcumin_4h_R1 1 VGINYQPPTVVPGGDLAK 18 0 Q9BQE3;F5H5D3;P0DPH8;P0DPH7;A0A1W2PQM2;P0DPH7-2;Q6PEY2;Q9NY65-2;Q9NY65;C9J2C0;V9GZ17;P68363;P68363-2;P68366-2;P68366 Q9BQE3;P68363;P68366-2 TUBA1C;TUBA3E;TUBA8;TUBA1B;TUBA4A Tubulin alpha-1C chain;Tubulin alpha-3E chain;Tubulin alpha-8 chain;Tubulin alpha-1B chain;Tubulin alpha-4A chain 0 0 235.93 2.67E-37 2199300 2242.8 1778.5 1992.2 1945.4 1891.6 2159.9 1717.4 1627 2431.8 1895.9 FALSE FALSE TRUE 2065.280013 1932.225615 2066.032685 1937.35045 1869.043905 1711.912393 1765.585622 2123.06481 2165.037624 1961.782384 1.052756937 0.984933717 1.053140604 0.987546053 0.952727438 0.872631137 0.899990558 1.08221219 1.103607435 1 10.9379493 -5.912126092 3.183579657 1.023812995 0.942255738 0.296460623 0.060444686 0.225136972 4.587034133 0.008114072 0.01542828 1.22E-06 5.912126092 -0.081557256 VGLQVVAVK ddPTM_HeLa_Curcumin_4h_R1 2 VGLQVVAVK 9 0 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 ; ; 162.5 1.40E-08 35579000 8793.3 6783.7 7649.4 7566.4 7973.6 14850.9 11261 9258.7 8175.4 6224.6 FALSE FALSE TRUE 8097.301026 7370.0528 7932.893493 7535.092242 7878.520028 11770.65594 11576.95335 12081.63501 7278.579074 6440.904387 1.257168332 1.144257446 1.231642797 1.16988109 1.223200898 1.827484966 1.797411149 1.875766862 1.130055445 1 12.65304756 -5.29282257 3.873226537 1.140187202 1.839181274 0.952391419 0.068531341 0.046991963 1.553217908 0.014911651 0.036844883 5.10E-06 5.29282257 0.698994072 VGLSPDSPAGDRNS(ph)VGSEGSVGSIR ddPTM_HeLa_Curcumin_4h_R1 1 VGLSPDSPAGDRNSVGSEGSVGSIR 25 1 Q8WXE0-2;Q8WXE0 Q8WXE0-2 CASKIN2 Caskin-2 1 0 VGLS(0.002)PDS(0.059)PAGDRNS(0.797)VGS(0.122)EGS(0.02)VGSIR 67.785 0.00039946 23838000 1215.1 1162 1190.7 1471.5 1374.9 1343.5 1427.2 659.96 1655.6 1059.3 TRUE FALSE FALSE 1118.923553 1262.438102 1234.828389 1465.411323 1358.505215 1064.842956 1467.243391 861.1787659 1473.984822 1096.110596 1.020812641 1.151743361 1.126554559 1.33691922 1.239386993 0.971474009 1.338590646 0.785667768 1.344740966 1 10.09817766 -7.28655197 4.680577498 1.009125948 1.149016271 0 0.188748527 0.269536453 15.33293603 0.024487194 0.028509741 5.17E-08 7.28655197 0.139890323 VGLVEDSPSTAGDGDDSPVVSLTVPSTS(ph)PPSSSGLSR ddPTM_HeLa_Curcumin_4h_R1 1 VGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSR 37 0 Q6VY07-2;Q6VY07;B4DF77 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 0 VGLVEDSPSTAGDGDDS(0.011)PVVS(0.32)LT(0.008)VPS(0.152)T(0.153)S(0.352)PPS(0.004)S(0.001)S(0.001)GLSR 92.798 9.76E-12 16409000 2179.8 1603.4 1861.4 1753.2 1596.6 2267.4 1735 1284.6 2143.5 1865.5 TRUE FALSE FALSE 2007.26653 1741.990751 1930.385121 1745.945723 1577.561588 1797.115681 1783.67943 1676.268626 1908.363413 1930.325986 1.039858834 0.902433456 1.000030635 0.904482318 0.817251386 0.930990773 0.92403016 0.868386293 0.98862235 1 10.91462879 -6.714351147 1.16517917 1.017649044 0.890452738 0.505767208 0.045931872 0.226316216 0.615515146 0.008417238 0.013098166 1.93E-07 6.714351147 -0.127196306 VGMADANS(ph)PPKPLSKPR ddPTM_HeLa_Curcumin_4h_R1 1 VGMADANSPPKPLSKPR 17 2 P26358;P26358-2;K7EJL0 P26358 DNMT1 DNA (cytosine-5)-methyltransferase 1 1 0 VGMADANS(0.971)PPKPLS(0.029)KPR 45.357 0.018999 65457000 3536.4 2843.9 3113.3 4067.6 3269.7 3348.9 2638.9 1946.8 3485.5 3259.2 TRUE FALSE FALSE 3256.490208 3089.714044 3228.681637 4050.769349 3230.710963 2654.30039 2712.940432 2540.370358 3103.14937 3372.456957 0.965613572 0.91616115 0.957367782 1.201133002 0.957969517 0.787052414 0.804440343 0.753269913 0.920144989 1 11.71958431 -5.292778324 4.767802249 0.992139672 0.782349449 0.607949813 0.076378282 0.09613161 5.63231569 0.010533651 0.025098512 5.10E-06 5.292778324 -0.209790223 VGNES(ph)PVQELK ddPTM_HeLa_Curcumin_4h_R1 3 VGNESPVQELK 11 0 Q5JSH3-2;Q5JSH3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 VGNES(1)PVQELK;VGNES(1)PVQELK;VGNES(1)PVQELK ;; 177.38 0.00018884 804623000 14230.1 12756.8 13242.5 13058.9 15189.4 15507 13607.4 15305.9 13075.1 10570.2 TRUE FALSE FALSE 13103.77257 13859.44095 13733.2787 13004.86573 15008.27633 12290.6734 13989.18702 19972.59845 11640.79424 10937.51366 1.19805771 1.267147304 1.255612484 1.18901481 1.37218355 1.123717307 1.279009787 1.826063863 1.064299858 1 13.4169972 -1.426162184 0.958099098 1.138159413 199.9999999 0.748773813 0.108284307 206.6523702 0.833781039 0.019997048 89425.50386 0.0374833 1.426162184 198.8618405 VGNES(ph)PVQELKQDVSK ddPTM_HeLa_Curcumin_4h_R1 1 VGNESPVQELKQDVSK 16 1 Q5JSH3-2;Q5JSH3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 VGNES(0.999)PVQELKQDVS(0.001)K 71.545 0.010072 28229000 3083.8 1888.9 1782.2 2422.8 1787.5 3186 2049.7 2606.4 2807.5 2274.4 TRUE FALSE FALSE 2839.713976 2052.168099 1848.2499 2412.775096 1766.18523 2525.187686 2107.209066 3401.079362 2499.524274 2353.435231 1.206625081 0.871988348 0.785341307 1.025214148 0.750471144 1.07297947 0.895375848 1.445155285 1.062074809 1 11.20055243 -11.88941519 13.23256895 0.841596915 1.0415656 0 0.198506058 0 0 0 0.026379208 1.29E-12 11.88941519 0.199968684 VGPAT(ph)PSAQVGK ddPTM_HeLa_Curcumin_4h_R1 1 VGPATPSAQVGK 12 0 E7ETY2;Q13428-6;Q13428-7;A0A3B3IS06;H0Y8Y7;Q13428-5;Q13428;Q13428-3;Q13428-4;Q13428-2;Q13428-8;A0A6I8PRA0 E7ETY2;Q13428 TCOF1 Treacle protein 1 0 VGPAT(0.981)PS(0.019)AQVGK 145.81 0.0024041 56640000 5424.5 4621.9 4799.6 4953 5959.8 7304.2 7526.1 3384.2 4737.7 3634.5 TRUE FALSE FALSE 4995.145101 5021.396441 4977.477398 4932.505798 5888.733277 5789.226585 7737.262111 4416.027001 4217.986163 3760.798604 1.328213932 1.335194189 1.323516072 1.31155808 1.565819895 1.539360969 2.057345507 1.174225867 1.121566616 1 11.87682333 -7.528331401 0.169979787 0.76198687 1.844955263 0.401530225 0.216697356 2.232741238 0.341734154 0.9961998 0.901246954 2.96E-08 7.528331401 1.082968392 ALENDFFNS(ph)PPRK ddPTM_HeLa_Curcumin_4h_R1 3 ALENDFFNSPPRK 13 1 F5H148;H3BMT1;Q9NYV6-2;Q9NYV6;A6NIE6;Q9NYV6-3 F5H148 RRN3;RRN3P2 RNA polymerase I-specific transcription initiation factor RRN3;Putative RRN3-like protein RRN3P2 1 0 ALENDFFNS(1)PPRK;ALENDFFNS(1)PPRK;ALENDFFNS(1)PPRK ;; 118.52 0.0033493 67345000 8095.7 7362.2 8003.9 7230.6 7110.4 8815 7096.4 2867.09 9168.1 7697.3 TRUE FALSE FALSE 7454.916802 7998.555763 8300.531575 7200.681693 7025.613124 6986.669634 7295.505885 3741.252543 8162.382367 7964.780602 0.935985205 1.004240564 1.042154453 0.904065291 0.882084953 0.877195491 0.915970728 0.469724495 1.024809442 1 12.95941891 -4.003258291 1.664422273 0.963325348 1.07E-22 0.867099582 0.056931289 0.539480683 0.832908821 0.008247896 1.019815272 9.93E-05 4.003258291 -0.963325348 down VGQAVDVVGQAGKPK ddPTM_HeLa_Curcumin_4h_R1 1 VGQAVDVVGQAGKPK 15 1 Q13200;Q13200-2;Q13200-3 Q13200 PSMD2 26S proteasome non-ATPase regulatory subunit 2 0 0 127.3 0.00066061 3119100 1798.8 1337.9 1499.3 1550.7 1453.9 2303.1 1442.1 1373.4 2108.4 1868.6 FALSE FALSE TRUE 1656.423082 1453.542114 1554.865377 1544.283614 1436.563192 1825.411099 1482.561445 1792.143338 1877.113795 1933.533711 0.85668177 0.751754214 0.804157366 0.798684608 0.742972923 0.944080307 0.766762657 0.926874627 0.970820309 1 10.9170242 -8.60979816 0.793537466 0.99139937 0.819052028 0.488404273 0.065663391 0.335772504 0.428119712 0.029844231 0.013551403 2.46E-09 8.60979816 -0.172347342 VGQQAIVLCIS(ph)PSKPNPVFK ddPTM_HeLa_Curcumin_4h_R1 2 VGQQAIVLCISPSKPNPVFK 20 1 C9JP85;Q16656-2;Q16656;Q16656-4 C9JP85 NRF1 Nuclear respiratory factor 1 1 0 VGQQAIVLCIS(0.974)PS(0.026)KPNPVFK;VGQQAIVLCIS(0.5)PS(0.5)KPNPVFK ; 96.708 0.00032744 95631000 5765.1 4104.5 5548.3 4834.5 4997.3 7389.2 5230.6 4459.5 5460.9 5363.7 TRUE FALSE FALSE 5308.786252 4459.274691 5753.924879 4814.49612 4937.710461 5856.596627 5377.356559 5819.181021 4861.852932 5550.088176 0.956522867 0.803460152 1.03672675 0.867462997 0.889663426 1.05522587 0.968877681 1.048484427 0.87599562 1 12.43829498 -5.243368204 24.97590361 0.95609618 1.018664158 0.196490074 0.074240643 1305.962105 1804947.957 0.010039583 0.025539999 5.71E-06 5.243368204 0.062567978 VGRPTASK(ac)ASK ddPTM_HeLa_Curcumin_4h_R1 2 VGRPTASKASK 11 2 Q9H1E3;Q9H1E3-2 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 0 1 ; VGRPTASK(1)ASK;VGRPTASK(1)ASK 115.92 0.00059606 25809000 5353.5 2734 4249.6 3785.2 4427.4 5408.2 5191.3 4772 3878.9 4271.4 FALSE TRUE FALSE 4929.764826 2970.314778 4407.093914 3769.537845 4374.606147 4286.478357 5336.953906 6226.960832 3453.394375 4419.830832 1.115374098 0.672042639 0.997118234 0.852869259 0.989767779 0.969828602 1.20750185 1.40886859 0.781340849 1 12.10977544 -4.503830713 2.650684275 1.000455855 1.411248006 0.517146175 0.13924915 0.204688865 2.496611564 0.018663315 0.144270666 3.13E-05 4.503830713 0.410792151 VGS(ph)AQPSPPDDLDAGGLAQR ddPTM_HeLa_Curcumin_4h_R1 1 VGSAQPSPPDDLDAGGLAQR 20 0 Q8N3D4;E9PIH6;H0YDZ9;A0A0U1RQH4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 0 VGS(0.747)AQPS(0.253)PPDDLDAGGLAQR 124.08 0.00042137 0 1082 823.31 822.51 945.17 1064.3 1066.6 889.42 1131.9 986.61 1111.3 TRUE FALSE FALSE 996.3585583 894.4732478 852.9929442 941.259137 1051.608918 845.3751369 914.3747314 1477.011099 878.3813514 1149.917592 0.866460836 0.777858565 0.74178615 0.818544862 0.91450807 0.735161496 0.795165443 1.28444952 0.763864608 1 10.16731476 -8.842677902 0.937268802 0.991861358 0.855021769 0 0.166478119 0.863041988 1.486813133 0.068475686 0.028501748 1.44E-09 8.842677902 -0.136839589 AET(ph)PPLPIPPPPPDIQPLER ddPTM_HeLa_Curcumin_4h_R1 2 AETPPLPIPPPPPDIQPLER 20 0 U3KPW8;A0A669KB72;Q8IX15;Q8IX15-3 U3KPW8 HOMEZ Homeobox and leucine zipper protein Homez 1 0 AET(1)PPLPIPPPPPDIQPLER;AET(1)PPLPIPPPPPDIQPLER ; 128.1 0.00021123 23295000 7942.7 6199.6 7031.1 7658.7 7848.6 8251.2 6686.3 2772.1 7861.3 7144.2 TRUE FALSE FALSE 7314.026914 6735.465799 7291.678751 7627.010329 7755.010571 6539.80811 6873.899583 3617.300529 6998.935058 7392.460418 0.989390068 0.911126393 0.986366966 1.031728261 1.049043232 0.884659199 0.929852741 0.489322949 0.94676666 1 12.8518389 -4.002840161 1.653291677 0.99062111 3.37E-14 0.894599331 0.049486742 0.415384746 0.632064143 0.006503504 0.802653256 9.93E-05 4.002840161 -0.99062111 down SLSLEAT(ph)SPLSAEK ddPTM_HeLa_Curcumin_4h_R1 1 SLSLEATSPLSAEK 14 0 H3BN63;Q86YC2 H3BN63 PALB2 Partner and localizer of BRCA2 1 0 SLSLEAT(0.752)S(0.246)PLS(0.002)AEK 129.37 0.0032258 11749000 1992.3 1386.2 1492.7 1823.4 1442 2050.1 1370.5 599.58 1975.6 1665.1 TRUE FALSE FALSE 1834.607353 1506.016951 1548.020775 1815.855254 1424.805092 1624.886151 1408.952541 782.3891819 1758.881623 1722.962101 1.064798437 0.874085942 0.898464786 1.053914798 0.826950918 0.943077128 0.817750164 0.45409541 1.02084754 1 10.75067525 -4.00278715 0.926941144 1.004724887 1.78E-38 0.783127211 0.079127541 1.04124348 0.490183087 0.012882769 1.175679393 9.94E-05 4.00278715 -1.004724887 down ASS(ph)PGYIDS(ph)PTYSR ddPTM_HeLa_Curcumin_4h_R1 1 ASSPGYIDSPTYSR 14 0 A0A0C4DGA7;O94929-2;O94929-3;O94929 A0A0C4DGA7 ABLIM3 Actin-binding LIM protein 3 2 0 AS(0.022)S(0.978)PGYIDS(1)PTYSR 164.7 0.00051978 14974000 4474.7 3570.1 3774.1 4673.4 4419.4 5043.6 4079.2 1667.6 4751.8 4589.3 TRUE FALSE FALSE 4120.522773 3878.683536 3913.971466 4654.062709 4366.701541 3997.500507 4193.651373 2176.043563 4230.539428 4748.777833 0.867701737 0.81677511 0.82420606 0.980054842 0.919542184 0.841795647 0.883101194 0.458232337 0.890869099 1 12.21334055 -4.002744343 1.863596595 0.917447383 6.15E-11 0.80386192 0.063040349 0.730575379 1.413363804 0.010847261 1.46464578 9.94E-05 4.002744343 -0.917447383 down VGS(ph)LTPPSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 VGSLTPPSSPK 11 0 Q2M2I8-2;Q2M2I8;E9PG46 Q2M2I8-2 AAK1 AP2-associated protein kinase 1 2 0 VGS(0.996)LT(0.004)PPS(0.016)S(0.984)PK 130.69 0.0065454 170880000 6576.8 6106.3 6064.2 6623.6 6556.9 7005.7 5948.9 4725.9 7053 6003.8 TRUE FALSE FALSE 6056.23934 6634.101363 6288.944587 6596.193298 6478.71325 5552.638849 6115.810123 6166.805155 6279.303546 6212.431603 0.974858111 1.067875155 1.012316109 1.061773186 1.042862709 0.893794766 0.984447075 0.992655622 1.010764214 1 12.60094235 -5.286457268 24.99717479 1.004690228 0.959713911 0.301676471 0.039695292 942.401948 941620.5697 0.00621089 0.013893332 5.17E-06 5.286457268 -0.044976316 VGS(ph)PLDYSLVDLPSTNGQS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 3 VGSPLDYSLVDLPSTNGQSPGK 22 0 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 2 0 VGS(0.997)PLDYS(0.003)LVDLPS(0.064)T(0.114)NGQS(0.821)PGK;VGS(0.883)PLDYS(0.117)LVDLPS(0.034)T(0.047)NGQS(0.919)PGK;VGS(0.923)PLDY(0.028)S(0.049)LVDLPS(0.273)T(0.244)NGQS(0.483)PGK ;; 99.254 0.00028114 12142700 6502.26 5727.2 6294.54 5966.78 6847.57 6253.21 5466.57 4140.8 6554.38 5378.98 TRUE FALSE FALSE 5987.59926 6222.233648 6527.82119 5942.091045 6765.9172 4956.223758 5619.947242 5403.310858 5835.380912 5565.899155 1.075764956 1.117920659 1.172824194 1.0675887 1.21560183 0.890462371 1.009710576 0.970788494 1.048416572 1 12.44239905 -5.227941458 24.99956122 1.066229054 0.962259511 0.417497368 0.069729717 670.0125542 500031.0028 0.010978923 0.027989074 5.92E-06 5.227941458 -0.103969543 ASDSSS(ph)PSCSSGPR ddPTM_HeLa_Curcumin_4h_R1 2 ASDSSSPSCSSGPR 14 0 H0YM74;Q92610 H0YM74 ZNF592 Zinc finger protein 592 1 0 AS(0.018)DSS(0.007)S(0.967)PS(0.006)CS(0.002)SGPR;AS(0.028)DS(0.006)S(0.071)S(0.895)PS(0.001)CSSGPR ; 223.58 1.37E-14 26524000 7226.5 5483 5886.4 6177.4 6004 7305.1 5198.5 2300.15 7023.7 6034.2 TRUE FALSE FALSE 6654.5149 5956.926088 6104.555162 6151.839556 5932.406221 5789.939915 5344.355919 3001.455146 6253.217682 6243.888001 1.065764616 0.95404115 0.977684923 0.985257832 0.950114131 0.927297209 0.855933982 0.480702912 1.00149421 1 12.60822894 -4.002319337 1.095869722 1.015081243 7.43E-19 0.94075335 0.037793079 0.503847558 0.33252844 0.006769131 0.674757396 9.95E-05 4.002319337 -1.015081243 down KASVVDPSTESSPAPQEGSEQPASPAS(ph)PLSSR ddPTM_HeLa_Curcumin_4h_R1 2 KASVVDPSTESSPAPQEGSEQPASPASPLSSR 32 1 Q66K14;Q66K14-2 Q66K14 TBC1D9B TBC1 domain family member 9B 1 0 KASVVDPSTESSPAPQEGS(0.001)EQPAS(0.445)PAS(0.453)PLS(0.051)S(0.051)R;KASVVDPSTESSPAPQEGS(0.001)EQPAS(0.35)PAS(0.42)PLS(0.053)S(0.175)R ; 133.39 3.79E-13 106593000 8122.2 6159.1 7163.7 7498.9 7336.3 7830.2 5221 2894.7 8092.4 7500.3 TRUE FALSE FALSE 7479.319299 6691.46516 7429.193024 7467.871539 7248.819414 6206.128255 5367.487208 3777.280704 7204.683966 7760.934867 0.963713706 0.86219834 0.957254912 0.962238656 0.93401369 0.799662458 0.691603177 0.486704343 0.928326818 1 12.92201473 -4.000486351 0.71069279 0.975098529 5.57E-16 0.930821768 0.040039752 0.630170783 0.173751113 0.006817943 0.535429503 9.99E-05 4.000486351 -0.975098529 down VGS(ph)PSGDAASSTPPSTR ddPTM_HeLa_Curcumin_4h_R1 2 VGSPSGDAASSTPPSTR 17 0 F8WEJ1;C9JF34;C9J222;F8WB78;F8WDE4;Q9H980;Q6PIY2;Q9NP87-2;Q9NP87;Q9NP87-3 F8WEJ1 POLM DNA-directed DNA/RNA polymerase mu 1 0 VGS(0.739)PS(0.117)GDAAS(0.117)S(0.026)TPPSTR;VGS(0.603)PS(0.358)GDAAS(0.029)S(0.008)T(0.002)PPSTR ; 95.822 0.0029703 28249000 2923.9 2744.7 2761.6 2318.02 3011.7 3868.9 2241.9 1816 3369.7 2887.7 TRUE FALSE FALSE 2692.47023 2981.939638 2863.947325 2308.428647 2975.787445 3066.446529 2304.80168 2369.69004 3000.052341 2988.04736 0.901080172 0.997955949 0.958467849 0.772554237 0.995897014 1.026237592 0.771340411 0.793056386 1.004017667 1 11.5449873 -4.747114467 24.96731529 0.949958143 0.782198275 0.493263743 0.070589499 153.5804642 267675.1806 0.009861706 0.036550104 1.79E-05 4.747114467 -0.167759868 VGS(ph)TKVPMT(ph)S(ph)GVKQKIMS(ph)VIR ddPTM_HeLa_Curcumin_4h_R1 1 VGSTKVPMTSGVKQKIMSVIR 21 3 H7C5W9;P16615-5;P16615-2;P16615-3;P16615-4;P16615 H7C5W9 ATP2A2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 4 0 VGS(0.806)T(0.376)KVPMT(0.909)S(0.909)GVKQKIMS(1)VIR 45.901 0.0085515 0 672.71 624.39 617.29 700.62 496.59 1084.6 739.45 454.42 811.38 789.87 TRUE FALSE FALSE 619.4642937 678.3594894 640.1673104 697.7210201 490.6684886 859.641734 760.1969769 592.9705661 722.373644 817.3179237 0.757923295 0.829982397 0.783253728 0.853671503 0.600339812 1.051783779 0.930111716 0.725507846 0.883834335 1 9.674753563 -9.407835383 1.097176706 1.001515333 0.816317558 0.124789011 0.118799591 0.555372483 1.180194244 0.079790345 0.019586644 3.91E-10 9.407835383 -0.185197776 VGSPFELVVSGNKR ddPTM_HeLa_Curcumin_4h_R1 1 VGSPFELVVSGNKR 14 1 Q6YHK3-3;Q6YHK3-2;Q6YHK3-4;Q6YHK3 Q6YHK3-3 CD109 CD109 antigen 0 0 78.287 0.0090849 0 0 0 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 0 0 0 0 0 0 0 0 0 0 VGSPQPS(ph)SSGGEK ddPTM_HeLa_Curcumin_4h_R1 2 VGSPQPSSSGGEK 13 0 V9GYB6;O94761 V9GYB6 RECQL4 ATP-dependent DNA helicase Q4 1 0 VGS(0.152)PQPS(0.392)S(0.392)S(0.064)GGEK;VGS(0.061)PQPS(0.674)S(0.203)S(0.061)GGEK ; 127.3 0.0018336 109110000 11995.1 10363.6 11582.8 11296.9 10166.6 9238.3 7291.4 4061.7 12537.4 10451.4 TRUE FALSE FALSE 11045.67518 11259.3834 12012.06876 11250.15642 10045.36994 7322.172443 7495.97706 5300.093632 11162.07859 10814.58537 1.021368346 1.041129458 1.110728553 1.04027626 0.928872406 0.677064556 0.693135872 0.490087548 1.032131904 1 13.40069073 -5.192710906 1.648558502 1.024186228 0.572453244 0.929351469 0.052317263 0.074337185 0.377089762 0.007907531 0.029865408 6.42E-06 5.192710906 -0.451732984 VGSVLQEGCGK ddPTM_HeLa_Curcumin_4h_R1 1 VGSVLQEGCGK 11 0 A0A087X1I3;P31040-3;P31040-2;P31040 A0A087X1I3 SDHA "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial" 0 0 95.618 0.014951 1487600 932.27 807.35 1006.8 1006.2 1020.1 1435.6 984.87 1182.8 1193.8 794.77 FALSE FALSE TRUE 858.4798458 877.1337365 1044.112894 1002.036611 1007.935974 1137.840377 1012.502802 1543.430275 1062.843127 822.3881983 1.043886388 1.066568973 1.269610746 1.218447216 1.225620669 1.383580625 1.231173798 1.87676608 1.292386161 1 9.683675751 -1 0.333660609 1.011707802 8.576817018 0.637807842 0.141430888 15.36193942 0.194616117 0.032635936 72.92170717 0.1 1 7.565109217 VGT(ph)GTMR ddPTM_HeLa_Curcumin_4h_R1 1 VGTGTMR 7 0 G5EA54;Q8TD10-2;Q8TD10 G5EA54 MIPOL1 Mirror-image polydactyly gene 1 protein 1 0 VGT(1)GTMR 62.715 0.013366 2495000 203.29 252.35 157.4 222.91 288.3 241.65 233.76 136.65 197.76 153.49 TRUE FALSE FALSE 187.199382 274.1620096 163.2333825 221.9876575 284.8622108 191.529066 240.3186765 178.3139559 176.0662228 158.8237661 1.178661019 1.726202673 1.02776421 1.397697983 1.79357421 1.205921952 1.513115338 1.122715827 1.108563454 1 7.311283 -7.488223595 7.111867602 1.077679995 1.400335966 0.27317242 0.231200831 0.186172004 28.07811846 0.038261429 0.042503929 3.25E-08 7.488223595 0.322655971 VGTEGLVDS(ph)FSQGLER ddPTM_HeLa_Curcumin_4h_R1 1 VGTEGLVDSFSQGLER 16 0 T1ECW5;O75170-6;O75170-2;O75170-4;O75170-3;O75170-5;O75170 T1ECW5 PPP6R2 Serine/threonine-protein phosphatase 6 regulatory subunit 2 1 0 VGTEGLVDS(0.997)FS(0.003)QGLER 139.12 0.00040159 7529300 932.43 955.54 1029 938.4 901.57 819.31 629.52 439.63 1035.2 964.68 TRUE FALSE FALSE 858.6271816 1038.13262 1067.135645 934.5171494 890.8193666 649.3758705 647.1826369 573.6711632 921.6411499 998.2025582 0.860173293 1.040001963 1.069057213 0.936199914 0.892423446 0.650545188 0.648348005 0.57470416 0.923300729 1 9.963188791 -5.286187572 2.489848387 0.952566091 0.612184342 0.870364374 0.059884053 0.095716764 1.156675529 0.010971061 0.030699043 5.17E-06 5.286187572 -0.34038175 VGTETVR ddPTM_HeLa_Curcumin_4h_R1 1 VGTETVR 7 0 O15067 O15067 PFAS Phosphoribosylformylglycinamidine synthase 0 0 106.42 0.016251 1176900 695.56 837.54 704.15 714.87 823.8 1113.1 800.61 642.43 851.9 979.64 FALSE FALSE TRUE 640.505692 909.9332256 730.2464184 711.9120574 813.976723 882.2305128 823.0729619 838.3039496 758.4487013 1013.682417 0.631860316 0.897651188 0.720389745 0.702302857 0.802989881 0.870322399 0.811963341 0.826988745 0.748211361 1 9.985390017 -9.580476277 1.369987486 0.99979838 0.765907067 0 0.108389631 0.285760559 0.963049245 0.061216611 0.014337911 2.63E-10 9.580476277 -0.233891313 VGVGK(ac)VIR ddPTM_HeLa_Curcumin_4h_R1 1 VGVGKVIR 8 1 Q00688 Q00688 FKBP3 Peptidyl-prolyl cis-trans isomerase FKBP3 0 1 VGVGK(1)VIR 102.77 0.010689 5135700 3190.3 2508.3 1754.6 1928.4 2001.5 2318.8 1684.3 1501 2226.9 1989.9 FALSE TRUE FALSE 2937.784389 2725.106275 1819.62702 1920.420792 1977.63342 1837.854742 1731.556925 1958.64799 1982.614641 2059.048877 1.42676768 1.323478187 0.883722111 0.932673728 0.960459677 0.892574607 0.840949889 0.951239192 0.962878863 1 11.00776236 -6.752005911 24.99854327 1.216306321 0.909614297 0.484425255 0.133161159 139.796515 370457.4086 0.02639996 0.037048944 1.77E-07 6.752005911 -0.306692024 VGVNGFGR ddPTM_HeLa_Curcumin_4h_R1 2 VGVNGFGR 8 0 P04406 P04406 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 ; ; 168.74 2.65E-09 176849000 7589.8 6113.5 6456.7 6876.9 6517.2 8025.4 6362.6 6905.8 7660.9 6379.5 FALSE FALSE TRUE 6989.059321 6641.923699 6695.990982 6848.44521 6439.486647 6360.841575 6541.117432 9011.34663 6820.518437 6601.18715 1.058757942 1.006171094 1.014361634 1.037456605 0.97550433 0.963590553 0.990900164 1.365110006 1.033226037 1 12.68850979 -4.258831766 24.99866516 1.016978003 1.365110129 0.933519925 0.028444975 51.92267421 497742.8245 0.004773378 0.043717853 5.51E-05 4.258831766 0.348132127 VGVSSKPDSS(ph)PVLSPGNK ddPTM_HeLa_Curcumin_4h_R1 2 VGVSSKPDSSPVLSPGNK 18 1 Q8N4C8;Q8N4C8-2;Q8N4C8-3;Q8N4C8-4;Q8N4C8-5 Q8N4C8 MINK1 Misshapen-like kinase 1 1 0 VGVSSKPDS(0.176)S(0.82)PVLS(0.004)PGNK;VGVSS(0.001)KPDS(0.128)S(0.444)PVLS(0.427)PGNK ; 83.894 0.0021979 283300000 10819.3 8687.7 8835.6 10474.5 10228.4 10756.2 8001 4551.3 11855.2 9326.9 TRUE FALSE FALSE 9962.940989 9438.626076 9163.055109 10431.15929 10106.43301 8525.242873 8225.486526 5938.970418 10554.71422 9651.009081 1.03232117 0.9779937 0.949440108 1.080836129 1.047189255 0.883352487 0.852292901 0.615373001 1.093638409 1 13.23646408 -4.213179839 1.108656769 1.014040176 0.397172299 0.864954949 0.049728055 0.411445827 0.375290783 0.006471515 0.30311959 6.12E-05 4.213179839 -0.616867878 VGWVT(ph)AGLVIGAGACYCIYRLTR ddPTM_HeLa_Curcumin_4h_R1 1 VGWVTAGLVIGAGACYCIYRLTR 23 1 Q9UH62;H3BV87;H3BM63 Q9UH62 ARMCX3 Armadillo repeat-containing X-linked protein 3 1 0 VGWVT(1)AGLVIGAGACYCIYRLTR 78.401 0.00020904 7084000 2901.1 2380.7 2526.8 2682.8 3089 663.29 2206.2 2255.4 3454.7 2950.6 TRUE FALSE FALSE 2671.474874 2586.4771 2620.445431 2671.699284 3052.165692 525.7161772 2268.100034 2943.061077 3075.728053 3053.13313 0.874994558 0.847155034 0.858280762 0.87506806 0.999683133 0.172189077 0.742876232 0.963947837 1.007400569 1 11.57607478 VHAPGLNLS(ph)GVGGK ddPTM_HeLa_Curcumin_4h_R1 2 VHAPGLNLSGVGGK 14 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VHAPGLNLS(1)GVGGK;VHAPGLNLS(1)GVGGK ; 160.46 0.00029144 43989000 9518.2 7206 8246.1 9001.8 8479.8 11164.6 8065.5 3071.2 8702.4 7071.6 TRUE FALSE FALSE 8764.824426 7828.854531 8551.70772 8964.552937 8378.683923 8848.936109 8291.796223 4007.594742 7747.768492 7317.337574 1.197816055 1.069904791 1.168691158 1.225111299 1.145045427 1.209310903 1.133171203 0.547684824 1.058823433 1 12.8371031 -4.260670017 24.89467113 1.120540954 0.547684636 0.863278051 0.069834186 20.6050606 666595.5417 0.012420282 0.100218738 5.49E-05 4.260670017 -0.572856318 VHDRS(ph)EEEEEEEEEEEEEQPR ddPTM_HeLa_Curcumin_4h_R1 3 VHDRSEEEEEEEEEEEEEQPR 21 1 Q5TAQ8;V9GY54;Q5TAQ9-2;Q5TAQ9;V9GYQ9 Q5TAQ8 DCAF8 DDB1- and CUL4-associated factor 8 1 0 VHDRS(1)EEEEEEEEEEEEEQPR;VHDRS(1)EEEEEEEEEEEEEQPR;VHDRS(1)EEEEEEEEEEEEEQPR ;; 162.72 1.50E-07 69913100 2729.38 2342.45 2626.05 2506.08 2783.21 3020.22 2198.29 2224.72 2558.62 2827.26 TRUE FALSE FALSE 2513.346693 2544.92094 2723.373723 2495.710505 2750.022039 2393.792327 2259.968101 2903.026887 2277.945787 2925.507075 0.859114892 0.869907635 0.930906559 0.853086471 0.940015515 0.818248689 0.772504746 0.992315798 0.778649899 1 11.51447099 -9.315356583 0.770203895 1.01060759 0.874715557 0 0.091181144 0.654381421 0.608456435 0.057067039 0.01130063 4.84E-10 9.315356583 -0.135892033 VHDYDMR ddPTM_HeLa_Curcumin_4h_R1 1 VHDYDMR 7 0 J3QR07;Q96MU7-2;Q96MU7 J3QR07 YTHDC1 YTH domain-containing protein 1 0 0 120.62 0.009354 4435800 1079.3 986.33 772.07 880.63 992.66 1195 1229.2 845.31 1228.2 851.56 FALSE FALSE TRUE 993.8722661 1071.58397 800.6835934 876.9861864 980.8231778 947.1435296 1263.688044 1103.041128 1093.469533 881.1516466 1.1279242 1.216117537 0.908678542 0.995272709 1.113115071 1.074892765 1.434132307 1.251817587 1.24095499 1 9.783246519 -4.775371364 24.27359899 1.061786554 1.342974881 0.479494061 0.105547635 71.04784226 123787.2777 0.012923275 0.039078948 1.68E-05 4.775371364 0.281188326 VHELNEEIGK ddPTM_HeLa_Curcumin_4h_R1 1 VHELNEEIGK 10 0 Q96HJ9-2;A0A0A6YYJ8;Q9Y383-3;Q9Y383-2;Q9Y383;A8MYV2;Q9NQ29-2;B8ZZ09;B8ZZ10;Q9NQ29;Q9NQ29-3 Q96HJ9-2;Q9NQ29 LUC7L2;LUC7L Putative RNA-binding protein Luc7-like 2;Putative RNA-binding protein Luc7-like 1 0 0 107.06 0.0070838 5554000 3661.3 3781.5 3429.1 4389.6 3615.5 3738.4 3914.4 3516.5 3766.7 3742.2 FALSE FALSE TRUE 3371.504242 4108.35601 3556.185463 4371.436998 3572.387524 2963.0137 4024.227529 4588.664662 3353.502434 3872.241171 0.8706855 1.060976274 0.918379126 1.128916512 0.922563282 0.765193481 1.03925023 1.185015204 0.866036563 1 11.91895309 -7.260846355 24.99996052 0.938934821 0.993660958 0.095140395 0.11753338 149.8079383 6315368.916 0.020287259 0.024057748 5.48E-08 7.260846355 0.054726137 (ac)AT(ph)AAETSAS(ph)EPEAESK ddPTM_HeLa_Curcumin_4h_R1 1 ATAAETSASEPEAESK 16 0 A0A499FI31;Q15020-4;Q15020;A0A494C0L2;F8W667;Q15020-3;Q15020-2 A0A499FI31 SART3 Squamous cell carcinoma antigen recognized by T-cells 3 2 0 AT(0.929)AAET(0.064)S(0.452)AS(0.555)EPEAESK 90.453 0.00028656 17439000 1875.4 1528.2 1624.9 1899.2 2007.7 1860.9 1492.3 676.43 2035.1 1832.8 TRUE FALSE FALSE 1726.960111 1660.290798 1685.120223 1891.341614 1983.759489 1474.928363 1534.169922 882.6703931 1811.854622 1896.489664 0.910608765 0.875454705 0.888547012 0.997285485 1.046016505 0.77771495 0.80895243 0.465423255 0.95537279 1 10.88911579 -3.997305661 1.100526182 0.951456216 1.37E-15 0.826054611 0.065845983 0.841891306 0.556234252 0.010448608 1.064006559 0.000100622 3.997305661 -0.951456216 down VGS(ph)DPVLMR ddPTM_HeLa_Curcumin_4h_R1 1 VGSDPVLMR 9 0 A0A2R8Y582;A0A2R8Y8D8;A0A2R8Y5E1;A0A2R8YFD4;Q13191-3;Q13191-2;Q13191 A0A2R8Y582 CBLB E3 ubiquitin-protein ligase CBL-B 1 0 VGS(1)DPVLMR 100.82 0.01265 7804800 5410.1 4649.7 5589.7 5954.4 4884.3 5312.7 4651.7 1806.7 5518.6 5267.6 TRUE FALSE FALSE 4981.884876 5051.599349 5796.859199 5929.762271 4826.057913 4210.786134 4782.214183 2357.554513 4913.223387 5450.648708 0.913998524 0.926788648 1.0635173 1.087900283 0.885409824 0.772529356 0.87736606 0.432527326 0.901401585 1 12.41221223 -3.996927682 1.043275343 0.96716144 5.67E-16 0.769849328 0.083994921 1.034742394 0.613498782 0.012738447 1.263187321 0.00010071 3.996927682 -0.96716144 down S(ph)LQLMDNR ddPTM_HeLa_Curcumin_4h_R1 1 SLQLMDNR 8 0 Q9H7D0 Q9H7D0 DOCK5 Dedicator of cytokinesis protein 5 1 0 S(1)LQLMDNR 92.792 0.019272 78628000 4036.8 3474.2 3964.1 3745.1 3308 3943.2 3392.2 1324 3862.6 3392.3 TRUE FALSE FALSE 3717.28302 3774.494367 4111.013033 3729.603769 3268.554261 3125.335871 3487.376002 1727.681505 3438.882444 3510.182172 1.059000028 1.075298712 1.171168 1.062510031 0.931163712 0.890362869 0.993502853 0.492191408 0.979687741 1 11.77733019 -3.996285681 1.490401553 1.034484735 5.68E-33 0.803662164 0.077451285 0.744960515 0.906283467 0.011392925 1.36927708 0.000100859 3.996285681 -1.034484735 down VHGPGIQSGTTNKPNK ddPTM_HeLa_Curcumin_4h_R1 2 VHGPGIQSGTTNKPNK 16 1 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 108.32 0.00043878 7515000 8387.5 7964.9 6760.5 6613.2 14720.9 22467 11647.3 8905.4 10637.5 6907.2 FALSE FALSE TRUE 7723.620525 8653.350465 7011.050077 6585.836331 14545.36288 17807.09094 11974.09189 11620.61546 9470.592864 7147.224686 1.080646106 1.210728758 0.980947205 0.921453658 2.035106425 2.491469308 1.675348463 1.625892004 1.325072777 1 12.80316743 -5.759212418 24.99966209 1.041306115 1.975019175 0.746636636 0.247490016 19.40330618 217814.6103 0.033985985 0.065429066 1.74E-06 5.759212418 0.93371306 VHGS(ph)PLELK ddPTM_HeLa_Curcumin_4h_R1 1 VHGSPLELK 9 0 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 VHGS(1)PLELK 82.505 0.013797 14264000 9432.8 8292.1 8452.6 9080.6 10623 14733 12878 6754.3 8431.2 6195.7 TRUE FALSE FALSE 8686.183927 9008.832175 8765.860792 9043.026883 10496.32766 11677.20972 13239.32202 8813.654977 7506.318454 6411.000114 1.354887502 1.405214789 1.367315651 1.410548545 1.637237167 1.821433398 2.065094648 1.374770679 1.170849839 1 12.64633372 -6.804504503 0.231148123 0.900025237 1.98184963 0.590158496 0.187274492 1.184076411 0.204531764 0.297341905 0.481893863 1.57E-07 6.804504503 1.081824393 VHGS(ph)PLELKQDNGSIEINIK ddPTM_HeLa_Curcumin_4h_R1 2 VHGSPLELKQDNGSIEINIK 20 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 VHGS(0.982)PLELKQDNGS(0.018)IEINIK;VHGS(0.997)PLELKQDNGS(0.003)IEINIK ; 69.98 0.0028492 60037000 2595.8 2118.4 2115.2 2330.1 2427.2 3511.2 3111.9 2068.63 2857.3 2424.6 TRUE FALSE FALSE 2390.339691 2301.505057 2193.591173 2320.458664 2398.257225 2782.937541 3199.211539 2699.345764 2543.861339 2508.85467 0.952761322 0.91735288 0.874339674 0.924907565 0.955917158 1.109246213 1.275168139 1.075927513 1.013953247 1 11.29281319 -5.144510709 3.707268738 0.959232457 1.178666421 0.716475607 0.059545098 0.094318649 2.320270681 0.008419561 0.023361515 7.17E-06 5.144510709 0.219433964 VHIDIGADGR ddPTM_HeLa_Curcumin_4h_R1 2 VHIDIGADGR 10 0 P31942;P31942-3;P31942-2;P31942-4;P31942-5;P31942-6 P31942 HNRNPH3 Heterogeneous nuclear ribonucleoprotein H3 0 0 ; ; 112.71 0.0051402 17077100 8129.2 5657.8 6317.5 6648.4 7154.8 8197.1 6417.3 7158.1 7630.7 6573 FALSE FALSE TRUE 7485.765242 6146.835021 6551.632107 6620.890682 7069.483683 6496.92906 6597.352167 9340.571738 6793.631301 6801.411261 1.100619409 0.903758762 0.963275393 0.973458365 1.039414235 0.955232497 0.969997536 1.373328473 0.998856126 1 12.73161841 -4.256745476 24.96891653 1.017694981 1.373328619 0.796299102 0.056650375 199.8226662 1062905.698 0.009443588 0.1020628 5.54E-05 4.256745476 0.355633638 VHIEIGPDGR ddPTM_HeLa_Curcumin_4h_R1 4 VHIEIGPDGR 10 0 P31943;G8JLB6;E9PCY7;H0YB39;H0YBD7;H0YBG7;P52597;P55795 P31943;P52597;P55795 HNRNPH1;HNRNPF;HNRNPH2 "Heterogeneous nuclear ribonucleoprotein H;Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;Heterogeneous nuclear ribonucleoprotein F;Heterogeneous nuclear ribonucleoprotein F, N-terminally processed;Heterogeneous nuclear ribonucleoprotein H2" 0 0 ;;; ;;; 166.66 0.00043643 127912000 28360.2 21662.7 24211.1 23782 24826.4 28671.6 25152.2 22229.5 24657.6 21594.7 FALSE FALSE TRUE 26115.46024 23535.12726 25108.38466 23683.59639 24530.36139 22724.78696 25857.90304 29007.17222 21952.72297 22345.11422 1.168732457 1.053256073 1.123663295 1.05990044 1.097795301 1.016991309 1.157206125 1.298143833 0.982439506 1 14.4476718 -9.481510143 1.161426533 0.998465238 1.120184441 0.327122909 0.074348876 0.553634263 1.308704815 0.055294975 0.012843217 3.30E-10 9.481510143 0.121719203 VHLVGIDIFT(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 VHLVGIDIFTGK 12 0 I3L397;I3L504;P63241;P63241-2;F8WCJ1;C9J7B5;C9J4W5;Q9GZV4;Q6IS14 I3L397 EIF5A;EIF5A2;EIF5AL1 Eukaryotic translation initiation factor 5A;Eukaryotic translation initiation factor 5A-1;Eukaryotic translation initiation factor 5A-2;Eukaryotic translation initiation factor 5A-1-like 1 0 VHLVGIDIFT(1)GK 102.5 0.0030616 0 3997.5 3102.9 3937.3 3829.9 4380.5 5451.2 3907.6 2684.4 4300.4 3734.9 TRUE FALSE FALSE 3681.093657 3371.10085 4083.219802 3814.052889 4328.265398 4320.559672 4017.236739 3502.861203 3828.656879 3864.687497 0.952494519 0.872282908 1.056545919 0.986898136 1.119952235 1.117958354 1.039472594 0.906376313 0.990676965 1 11.91613605 VHLVGIDIFTGK ddPTM_HeLa_Curcumin_4h_R1 4 VHLVGIDIFTGK 12 0 I3L397;I3L504;P63241;P63241-2;F8WCJ1;C9J7B5;C9J4W5;Q9GZV4;Q6IS14 I3L397 EIF5A;EIF5A2;EIF5AL1 Eukaryotic translation initiation factor 5A;Eukaryotic translation initiation factor 5A-1;Eukaryotic translation initiation factor 5A-2;Eukaryotic translation initiation factor 5A-1-like 0 0 ;;; ;;; 207.34 1.57E-20 63642550 28231.82 21426.92 24510.27 21533.86 22466.47 39392.6 28693.46 26320.93 27710.15 25155.91 FALSE FALSE TRUE 25997.24166 23278.96749 25418.64217 21444.75859 22198.57202 31222.13071 29498.52126 34346.06039 24670.41587 26030.076 0.9987386 0.894310393 0.976510486 0.823845408 0.852804733 1.199463679 1.133247604 1.319475993 0.947765803 1 14.6678919 -5.238557713 21.61320207 0.967584138 1.208981318 0.734067507 0.077287303 69.41257759 65563.42332 0.011746331 0.029902596 5.77E-06 5.238557713 0.24139718 VHLVGIDIFTGKK ddPTM_HeLa_Curcumin_4h_R1 2 VHLVGIDIFTGKK 13 1 I3L397;I3L504;P63241;P63241-2;F8WCJ1;C9J7B5;C9J4W5;Q9GZV4;Q6IS14 I3L397 EIF5A;EIF5A2;EIF5AL1 Eukaryotic translation initiation factor 5A;Eukaryotic translation initiation factor 5A-1;Eukaryotic translation initiation factor 5A-2;Eukaryotic translation initiation factor 5A-1-like 0 0 ; ; 95.483 0.0010879 6938400 10330.8 8098.7 8094.8 7408.3 7856.6 16195.3 11478 11714.2 10388.6 10714.9 FALSE FALSE TRUE 9513.106279 8798.715541 8394.800409 7377.646418 7762.915176 12836.21222 11800.04179 15285.80565 9248.996571 11087.24198 0.858022789 0.793589204 0.757158582 0.665417642 0.700166479 1.157746196 1.064290092 1.378684229 0.834201742 1 13.43661291 -4.62608585 1.531146889 0.877278848 1.36935493 0.632300476 0.130190721 0.379590949 1.302633017 0.02209195 0.228273167 2.37E-05 4.62608585 0.492076083 VHNDAQSFDY(ph)DHDAFLGAEEAK ddPTM_HeLa_Curcumin_4h_R1 1 VHNDAQSFDYDHDAFLGAEEAK 22 0 O43852-2;O43852;O43852-4;O43852-3;O43852-9;O43852-5;O43852-12;O43852-13;O43852-14;O43852-7;O43852-11;O43852-8;O43852-10;O43852-6 O43852-2 CALU Calumenin 1 0 VHNDAQS(0.018)FDY(0.982)DHDAFLGAEEAK 67.11 0.013958 10966000 1614.7 1359.1 1536.4 1579.9 1936.8 1633 954.14 996.96 1964.8 1583.6 TRUE FALSE FALSE 1486.894791 1476.574548 1593.340336 1573.362792 1913.704925 1294.297392 980.9106005 1300.928515 1749.266356 1638.629982 0.907401187 0.901103095 0.972361273 0.96016966 1.167868857 0.789865562 0.59861629 0.79391231 1.067517606 1 10.6782744 -5.011343375 23.85719109 0.965353685 0.695758378 0.655920662 0.08904135 125.5391665 264035.6485 0.011394174 0.031157119 9.74E-06 5.011343375 -0.269595307 VHNDAQSFDYDHDAFLGAEEAK ddPTM_HeLa_Curcumin_4h_R1 2 VHNDAQSFDYDHDAFLGAEEAK 22 0 O43852-2;O43852;O43852-4;O43852-3;O43852-9;O43852-5;O43852-12;O43852-13;O43852-14;O43852-7;O43852-11;O43852-8;O43852-10;O43852-6 O43852-2 CALU Calumenin 0 0 ; ; 94.176 6.99E-05 21184100 3531.9 2944.26 3605 3415.8 3832.8 3872.1 2660.9 1930.77 3252.8 3234.3 FALSE FALSE TRUE 3252.346388 3198.748715 3738.604471 3401.666325 3787.096363 3068.982812 2735.557693 2519.452885 2895.975978 3346.691684 0.971809385 0.955794264 1.117104539 1.016426563 1.13159404 0.917019882 0.817391607 0.75281894 0.865324999 1 11.70851993 -4.830351309 2.917267538 1.005120189 0.773091846 0.5925101 0.073573708 0.108956589 1.831148834 0.00856615 0.034163205 1.48E-05 4.830351309 -0.232028344 VHS(ph)PCPTSGSEK ddPTM_HeLa_Curcumin_4h_R1 1 VHSPCPTSGSEK 12 0 X6RLP6;Q96LT9-2;Q96LT9 X6RLP6 RNPC3 RNA-binding protein 40 1 0 VHS(0.977)PCPT(0.019)S(0.005)GSEK 101.53 0.0084425 3446400 1568.2 1327.1 1308 1392.5 1690.1 1883.3 1667.7 1078.3 1443.2 1275.6 TRUE FALSE FALSE 1444.075315 1441.808611 1356.475631 1386.738204 1669.946661 1492.682351 1714.491174 1407.068706 1284.884571 1319.927005 1.094056951 1.092339656 1.027689884 1.050617344 1.265181071 1.1308825 1.298928779 1.066020091 0.973451233 1 10.36624243 -5.781065398 24.68469425 1.048437377 1.193774882 0.524576835 0.069889769 117.0585007 147230.5287 0.009495567 0.01723014 1.66E-06 5.781065398 0.145337505 VHS(ph)PPASLVPR ddPTM_HeLa_Curcumin_4h_R1 2 VHSPPASLVPR 11 0 Q9BTE3;Q9BTE3-2;Q9BTE3-3 Q9BTE3 MCMBP Mini-chromosome maintenance complex-binding protein 1 0 VHS(1)PPASLVPR;VHS(1)PPASLVPR ; 122.66 0.0018203 26754000 3446.6 3150 3384.1 3373.9 3768 3865.3 3040.3 3144.7 3724 3544.8 TRUE FALSE FALSE 3173.797973 3422.271964 3509.517723 3359.939696 3723.069061 3063.593209 3125.602635 4103.504554 3315.486517 3667.981536 0.865270979 0.93301232 0.956798089 0.916018705 1.015018485 0.835225908 0.852131507 1.118736426 0.903899457 1 11.84077066 VHSAVITVPAYFNDSQR ddPTM_HeLa_Curcumin_4h_R1 1 VHSAVITVPAYFNDSQR 17 0 P54652 P54652 HSPA2 Heat shock-related 70 kDa protein 2 0 0 86.777 0.0047351 71192000 1873.5 1640.9 1804.4 1358.1 1433.2 4212.7 2061.8 1830.6 2052.4 1919.8 FALSE FALSE TRUE 1725.210498 1782.732084 1871.272651 1352.480542 1416.110026 3338.938533 2119.648559 2388.741513 1827.256855 1986.512907 0.868461761 0.897417821 0.94198867 0.68083149 0.712862233 1.680803845 1.067019777 1.202479734 0.919831353 1 10.95602245 -5.281182996 24.99568815 0.900997123 1.291793062 0.580474565 0.175101417 466.0271661 589996.1143 0.024876301 0.055696114 5.23E-06 5.281182996 0.390795939 VHSEAIS(ph)PAPEEK ddPTM_HeLa_Curcumin_4h_R1 2 VHSEAISPAPEEK 13 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 VHS(0.002)EAIS(0.998)PAPEEK;VHS(0.002)EAIS(0.998)PAPEEK ; 75.376 0.013223 155063000 18098.5 14909.7 15030.4 15962.2 14688.1 19463.8 15430.5 15895.1 19054.6 15686.1 TRUE FALSE FALSE 16665.98463 16198.42803 15587.43985 15896.15265 14512.954 15426.78848 15863.4383 20741.44282 16964.35805 16231.19081 1.026787549 0.997981493 0.960338649 0.979358375 0.894139818 0.950440954 0.977342851 1.277875608 1.045170268 1 13.98648123 -4.259602674 24.94424627 0.992387358 1.277875707 0.822083113 0.041102249 53.58040034 727612.5611 0.00622582 0.053757386 5.50E-05 4.259602674 0.285488349 NSS(ph)EASSGDFLDLK ddPTM_HeLa_Curcumin_4h_R1 3 NSSEASSGDFLDLK 14 0 Q9UK76;J3KT51;Q9UK76-2;Q9UK76-3;J3KSH8 Q9UK76;Q9UK76-3 HN1 "Hematological and neurological expressed 1 protein;Hematological and neurological expressed 1 protein, N-terminally processed" 1 0 NS(0.164)S(0.835)EAS(0.001)SGDFLDLK;NS(0.011)S(0.535)EAS(0.447)S(0.007)GDFLDLK;NS(0.257)S(0.743)EASSGDFLDLK ;; 237.34 1.86E-22 152091000 11998.3 11123 12627.1 12568.8 16005 16402.4 16630.1 19307.3 10880.1 11127.3 TRUE FALSE FALSE 11048.62189 12084.42256 13095.07143 12516.79364 15814.15083 13000.35735 17096.69585 25194.00689 9686.580251 11513.97285 0.959583807 1.049544125 1.137319986 1.087095984 1.373474737 1.129093973 1.484865048 2.188124571 0.841289134 1 13.49109809 -1 0.584127355 0.998546994 66.70538084 0.905723561 0.112906319 25.93270365 0.194770665 0.018105726 2171.479141 0.1 1 65.70683385 up VHVGDEDFVHLR ddPTM_HeLa_Curcumin_4h_R1 3 VHVGDEDFVHLR 12 0 P04080 P04080 CSTB Cystatin-B 0 0 ;; ;; 169.82 3.78E-05 36621800 8035.01 6494.8 8644.28 7196.62 10225.24 10078.89 8111.66 9516.3 7905.1 6911.41 FALSE FALSE TRUE 7399.03048 7056.181572 8964.644621 7166.842293 10103.31069 7988.414601 8339.251348 12417.77606 7037.930308 7151.580983 1.03460067 0.986660375 1.253519277 1.002133977 1.412738067 1.117013793 1.166071022 1.736367957 0.984108315 1 12.80404649 -1 0.470871321 1.025558646 16.62209334 0.640913281 0.138353944 36.8770438 0.380149328 0.026593901 564.2501737 0.1 1 15.59653469 VHVQFFDDS(ph)PTR ddPTM_HeLa_Curcumin_4h_R1 5 VHVQFFDDSPTR 12 0 F8WAX8;A0A087WWJ1;P52701-2;P52701;C9JH55;C9J8Y8;C9J7Y7;A0A494C0M1 F8WAX8 MSH6 DNA mismatch repair protein Msh6 1 0 VHVQFFDDS(0.927)PT(0.073)R;VHVQFFDDS(0.988)PT(0.012)R;VHVQFFDDS(0.97)PT(0.03)R;VHVQFFDDS(0.961)PT(0.039)R;VHVQFFDDS(0.991)PT(0.009)R ;;;; 205.87 5.06E-09 95679000 13303.6 10262.48 12858.4 12036.7 12112.2 15027.6 12309.4 8112.01 12648 11811.4 TRUE FALSE FALSE 12250.60602 11149.52304 13334.94362 11986.89532 11967.76993 11910.70636 12654.76863 10585.32451 11260.54604 12221.84527 1.002353225 0.912261839 1.091074492 0.98077623 0.979211376 0.974542395 1.035422095 0.866098717 0.921345819 1 13.5771745 -4.251292333 24.66822181 0.998334828 0.866098629 0.339593159 0.049569134 759.5272898 1846423.264 0.005289881 0.097109456 5.61E-05 4.251292333 -0.132236199 VIAINVDDPDAANYNDINDVKR ddPTM_HeLa_Curcumin_4h_R1 1 VIAINVDDPDAANYNDINDVKR 22 1 Q15181 Q15181 PPA1 Inorganic pyrophosphatase 0 0 80.98 0.0011905 19919000 2134.2 1452 1859.5 1800.7 1798.4 2320.8 1935.5 1630.1 2031.9 1997.6 FALSE FALSE TRUE 1965.275818 1577.50441 1928.414706 1793.249181 1776.955255 1839.439919 1989.804921 2127.109986 1809.005654 2067.016451 0.950778992 0.763179417 0.932945988 0.867554382 0.859671559 0.889900958 0.962645904 1.029072596 0.875177192 1 11.01333416 -7.50094958 12.39553548 0.978316159 0.897918364 0.005880699 0.073708717 0.856672838 482.112396 0.011795918 0.012826479 3.16E-08 7.50094958 -0.080397794 VIDFDENTALDDAEEESFR ddPTM_HeLa_Curcumin_4h_R1 2 VIDFDENTALDDAEEESFR 19 0 Q14257;Q14257-2;H0YL43 Q14257 RCN2 Reticulocalbin-2 0 0 ; ; 246.66 7.68E-33 14444600 3279.3 2440.4 2726.6 3329.4 2939.2 3378.3 2468.6 2158.7 2837.9 2631.4 FALSE FALSE TRUE 3019.739945 2651.337302 2827.650195 3315.623825 2904.15196 2677.602499 2537.862272 2816.877693 2526.58947 2722.840954 1.109040152 0.973739321 1.038492605 1.21770749 1.066588908 0.983385568 0.932064089 1.034536258 0.927924 1 11.410897 -5.24597375 9.089030939 1.059278928 0.978089603 0.110751251 0.078407886 0.339357639 180.081894 0.010292498 0.02552481 5.68E-06 5.24597375 -0.081189325 VIDFDENTALDDAEEESFRK ddPTM_HeLa_Curcumin_4h_R1 1 VIDFDENTALDDAEEESFRK 20 1 Q14257;Q14257-2;H0YL43 Q14257 RCN2 Reticulocalbin-2 0 0 179.07 2.42E-07 5937000 1536.8 1303.6 1179.5 1305.7 1436.3 1439.2 1184 1077 1301.6 1227 FALSE FALSE TRUE 1415.160658 1416.277375 1223.213308 1300.297359 1419.173061 1140.693697 1217.219853 1405.372342 1158.817736 1269.638159 1.114617302 1.115496857 0.963434581 1.024147983 1.117777574 0.898439992 0.958713981 1.106907769 0.912714956 1 10.31020168 -6.755032028 24.99969236 1.06024005 1.009424788 0 0.083586523 293.9050555 1146731.749 0.01203825 0.016793166 1.76E-07 6.755032028 -0.050815261 VIDPATATSVDLR ddPTM_HeLa_Curcumin_4h_R1 1 VIDPATATSVDLR 13 0 P50991-2;P50991 P50991-2 CCT4 T-complex protein 1 subunit delta 0 0 99.973 0.0078516 4403500 1158.6 726.61 660.52 618.34 695.35 1074.6 935.05 703.89 909.14 805 FALSE FALSE TRUE 1066.895587 789.4149307 684.9994523 615.7814729 687.0584054 851.7158468 961.2849864 918.5028207 809.4096166 832.9736901 1.280827474 0.947706921 0.822354248 0.73925681 0.824826058 1.022500299 1.154040035 1.10267927 0.971710903 1 9.702127118 -7.150516497 9.255544279 1.13253926 0.937982477 0.136585807 0.145623662 0.405280814 31.30838495 0.028249278 0.03461749 7.07E-08 7.150516497 -0.194556783 VIEEEWQQVDR ddPTM_HeLa_Curcumin_4h_R1 1 VIEEEWQQVDR 11 0 P42166 P42166 TMPO "Lamina-associated polypeptide 2, isoform alpha;Thymopoietin;Thymopentin" 0 0 162.38 0.0026192 17820000 616.38 514.4 505.15 574.29 542.63 598.2 436.29 368.61 628.86 338.4 FALSE FALSE TRUE 567.5928726 558.8624439 523.8713034 571.9137401 536.1594917 474.1265769 448.5311232 480.9974921 559.8756313 350.1593748 1.620955809 1.59602308 1.496093896 1.633295526 1.531187026 1.354030796 1.280934213 1.373653047 1.598916584 1 8.451867903 -9.351139235 1.050649596 0.997264278 1.49368109 0 0.214216792 0.249524503 0.488665195 0.092187624 0.023537787 4.46E-10 9.351139235 0.496416811 VIEETEER ddPTM_HeLa_Curcumin_4h_R1 1 VIEETEER 8 0 A0A075B730;P58107 A0A075B730 EPPK1 Epiplakin 0 0 105.57 0.0089638 3964200 2474.1 2248.1 2414.5 2194.4 2930 2611.3 2333.4 1078.2 2168.6 2119.4 FALSE FALSE TRUE 2278.272374 2442.415747 2503.983494 2185.320154 2895.061664 2069.686945 2398.868924 1406.938217 1930.710006 2193.048992 1.038860683 1.11370779 1.141781831 0.996475757 1.320108066 0.943748613 1.093851041 0.641544362 0.880377051 1 11.09872233 -4.257750963 24.90341475 1.050738896 0.641544197 0.540301332 0.115239927 178.9789429 1208373.07 0.013537439 0.135040486 5.52E-05 4.257750963 -0.4091947 VIET(ph)PENDFK ddPTM_HeLa_Curcumin_4h_R1 2 VIETPENDFK 10 0 Q9H0G5;A0A024QZ33 Q9H0G5 NSRP1;CCDC55 Nuclear speckle splicing regulatory protein 1 1 0 VIET(1)PENDFK;VIET(1)PENDFK ; 124.21 0.011126 60591000 10084.4 8240.6 9370.3 9160.3 9853.3 10895.1 9264.9 3663.9 8663.8 7871 TRUE FALSE FALSE 9286.209099 8952.880745 9717.571561 9122.397106 9735.805833 8635.333447 9524.848159 4781.006243 7713.402816 8144.516664 1.140179274 1.099252554 1.193142818 1.120066111 1.195381658 1.060263464 1.169479854 0.587021482 0.947066982 1 12.99161337 -4.25628194 24.84573445 1.095068217 0.58702125 0.799100662 0.077491701 164.5186654 792533.3115 0.010553279 0.118521729 5.54E-05 4.25628194 -0.508046967 VIFGLFGK ddPTM_HeLa_Curcumin_4h_R1 1 VIFGLFGK 8 0 P23284 P23284 PPIB Peptidyl-prolyl cis-trans isomerase B 0 0 137.44 0.00094215 19689000 56.948 0 154.16 64.073 119.14 178.72 159.44 0 0 121.19 FALSE FALSE TRUE 52.44050571 0 159.8733052 63.8078829 117.7193333 141.6514574 163.9134573 0 0 125.4013435 0.418181371 0 1.274893082 0.508829341 0.938740607 1.129584847 1.307110855 0 0 1 6.970408994 VIFLEDDDVAAVVDGR ddPTM_HeLa_Curcumin_4h_R1 2 VIFLEDDDVAAVVDGR 16 0 A0A6I8PRN4;A0A6I8PTT9;Q06210-2;Q06210 A0A6I8PRN4 GFPT1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 0 0 ; ; 195.72 5.24E-24 2643700 1719.02 1117.6 1259.52 1587.63 1235.42 1451.54 877.12 1056.08 1317.65 1551.79 FALSE FALSE TRUE 1582.957753 1214.200364 1306.198919 1581.060808 1220.688423 1150.474242 901.7296266 1378.07393 1173.107092 1605.714587 0.985827597 0.756174462 0.813468925 0.984646226 0.760215068 0.716487383 0.561575285 0.858230934 0.730582571 1 10.64899976 -6.351826015 0.467046224 1.009657603 0.675751011 0.007041054 0.134263636 0.636142305 0.271899514 0.032603664 0.08823714 4.45E-07 6.351826015 -0.333906592 VIGAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VIGAKK 6 1 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 0 1 ; VIGAK(1)K;VIGAK(1)K 91.26 0.015339 272210000 32017 36399 29650 23740 25584 33465 28550 17597.1 23983 28976 FALSE TRUE FALSE 29482.82067 39545.16737 30748.85508 23641.77017 25278.92751 26523.98177 29351.03616 22962.37478 21352.1249 29982.91384 0.983320728 1.318923423 1.025545924 0.788508091 0.843111101 0.88463656 0.978925408 0.765848673 0.71214309 1 14.87185298 -6.278323021 23.71799704 1.023911479 0.860542369 0.21508281 0.146802036 372.2441093 522924.6429 0.017496664 0.026779502 5.27E-07 6.278323021 -0.16336911 VIGAK(ac)K(ac)DQYFLDK ddPTM_HeLa_Curcumin_4h_R1 1 VIGAKKDQYFLDK 13 2 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 0 2 VIGAK(1)K(1)DQYFLDK 190.1 7.86E-13 977690 249.42 175.73 168.67 296.17 251.59 132.46 374.91 246.4 350.67 232.26 FALSE TRUE FALSE 229.6781438 190.9193182 174.9210586 294.944527 248.5899536 104.9863029 385.4289656 321.5262257 312.2023783 240.3310177 0.955674161 0.794401488 0.727833886 1.227242866 1.034364835 0.436840421 1.603742077 1.337847394 1.299051539 1 7.908879048 -4.731448524 24.99996317 0.940143225 1.47079523 0.442789275 0.240608336 120.0372053 100059.6477 0.027503717 0.102881845 1.86E-05 4.731448524 0.530652005 VIGAK(ac)K(ac)DQYFLDKK ddPTM_HeLa_Curcumin_4h_R1 2 VIGAKKDQYFLDKK 14 3 Q9UQE7 Q9UQE7 SMC3 Structural maintenance of chromosomes protein 3 0 2 ; VIGAK(1)K(1)DQYFLDKK;VIGAK(1)K(1)DQYFLDKK 215.87 1.23E-27 37448300 9027.5 7160 7514.7 7514.9 7449.8 11059 7867.4 7812.3 9955.8 8868.7 FALSE TRUE FALSE 8312.963849 7778.878496 7793.201393 7483.805335 7360.966001 8765.238739 8088.13807 10194.23431 8863.673648 9176.886665 0.905858833 0.847659863 0.849220621 0.815505913 0.802120182 0.955142965 0.881359699 1.110859781 0.96586936 1 13.16378908 -8.702790571 0.896294041 0.992949371 0.889540489 0.138585526 0.08428884 0.661263126 1.062349269 0.037223246 0.017029961 1.98E-09 8.702790571 -0.103408882 VIGGDDLSTLTGK ddPTM_HeLa_Curcumin_4h_R1 2 VIGGDDLSTLTGK 13 0 P00492 P00492 HPRT1 Hypoxanthine-guanine phosphoribosyltransferase 0 0 ; ; 139.31 6.71E-10 1442300 1629.19 1310.41 1393.26 1416.39 1616.66 1500.63 1287.64 883.28 1480.44 1258.52 FALSE FALSE TRUE 1500.237892 1423.676001 1444.895441 1410.529353 1597.382385 1189.382422 1323.767713 1152.588006 1318.039436 1302.253476 1.152032166 1.093240316 1.109534716 1.083145009 1.226629389 0.913326356 1.016520775 0.885071936 1.012122033 1 10.34679457 -5.227628411 24.97659626 1.087695157 0.946127769 0.524172419 0.068652073 467.3465681 345234.2519 0.01066547 0.027189975 5.92E-06 5.227628411 -0.141567389 VIGQDHDFSES(ph)SEEEAPAEASSGALR ddPTM_HeLa_Curcumin_4h_R1 1 VIGQDHDFSESSEEEAPAEASSGALR 26 0 P23497;E9PHV6;P23497-7;P23497-6;P23497-2;P23497-3;P23497-4;P23497-5;H7C1G8;H7C4B4 P23497 SP100 Nuclear autoantigen Sp-100 1 0 VIGQDHDFS(0.001)ES(0.971)S(0.028)EEEAPAEASSGALR 148.6 1.43E-08 5899900 2077.1 1750.7 1790.9 1942.5 1745.5 1764.1 957.13 1238.8 1787.3 1582 TRUE FALSE FALSE 1912.695343 1902.022707 1857.272329 1934.46245 1724.686053 1398.205774 983.9844918 1616.504417 1591.237662 1636.974382 1.168433278 1.161913545 1.134576295 1.181730436 1.053581578 0.854140291 0.601099506 0.987495244 0.97206021 1 10.67681603 -5.23655208 3.536403688 1.099517265 0.782413102 0.58607103 0.10929846 0.115355101 3.071031684 0.015290057 0.040494837 5.80E-06 5.23655208 -0.317104162 VIGSGCNLDS(ph)AR ddPTM_HeLa_Curcumin_4h_R1 1 VIGSGCNLDSAR 12 0 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;F5H5G7;F5H155;A0A087WUM2;G3XAP5;F5H245;Q6ZMR3;P07864;P00338;P00338-3;P00338-4;P00338-5;P00338-2 A0A5F9ZHM4;P00338 LDHB;LDHC;LDHAL6A;LDHA L-lactate dehydrogenase B chain;L-lactate dehydrogenase;L-lactate dehydrogenase A-like 6A;L-lactate dehydrogenase C chain;L-lactate dehydrogenase A chain 1 0 VIGSGCNLDS(1)AR 109.99 0.0055823 16044000 814.24 1056.4 1166.8 810.44 809.59 976.37 1130.9 593.72 1129.1 1293.4 TRUE FALSE FALSE 749.7920448 1147.710509 1210.042634 807.086614 799.936168 773.859856 1162.63001 774.7424948 1005.240555 1338.345554 0.560238006 0.857559175 0.90413319 0.603048003 0.597705253 0.578221263 0.868706895 0.578880763 0.751106881 1 10.38623494 -9.485145328 1.153323478 1.00487381 0.686937063 0.113354812 0.148133797 0.383780518 0.890487198 0.100045806 0.0229383 3.27E-10 9.485145328 -0.317936747 VIGSGCNLDSAR ddPTM_HeLa_Curcumin_4h_R1 2 VIGSGCNLDSAR 12 0 A0A5F9ZHM4;P07195;A0A3B3IS95;A8MW50;F5H5G7;F5H155;A0A087WUM2;G3XAP5;F5H245;Q6ZMR3;P07864;P00338;P00338-3;P00338-4;P00338-5;P00338-2 A0A5F9ZHM4;P00338 LDHB;LDHC;LDHAL6A;LDHA L-lactate dehydrogenase B chain;L-lactate dehydrogenase;L-lactate dehydrogenase A-like 6A;L-lactate dehydrogenase C chain;L-lactate dehydrogenase A chain 0 0 ; ; 197.73 2.15E-14 33117000 5101.1 3394.1 4409.5 3242.2 4612.1 7037.9 3593.2 3261.8 4323.3 4498.7 FALSE FALSE TRUE 4697.342552 3687.47088 4572.919949 3228.784635 4557.10372 5578.160207 3694.015521 4256.307805 3849.044806 4655.02949 1.009089752 0.792147695 0.982361113 0.693612069 0.978963448 1.198308242 0.793553624 0.914346045 0.826857234 1 12.18457459 VIISAPS(ph)ADAPMFVMGVNHEK ddPTM_HeLa_Curcumin_4h_R1 1 VIISAPSADAPMFVMGVNHEK 21 0 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 1 0 VIIS(0.014)APS(0.986)ADAPMFVMGVNHEK 93.776 0.00017049 7844900 1272.1 951.96 1320 1086.9 1160.6 1759.6 1549 1159.5 1099.1 1182.7 TRUE FALSE FALSE 1171.411943 1034.243181 1368.920361 1082.402696 1146.760603 1394.639125 1592.460771 1513.026212 978.5314798 1223.798737 0.957193293 0.84510888 1.118582917 0.88446136 0.937049997 1.139598435 1.301244006 1.236335818 0.7995853 1 10.2571506 -5.044548132 3.340195773 0.97018216 1.265952959 0.693143264 0.089089117 0.081801907 1.833250829 0.009522339 0.029069857 9.03E-06 5.044548132 0.295770799 VIISAPSADAPMFVMGVNHEK ddPTM_HeLa_Curcumin_4h_R1 7 VIISAPSADAPMFVMGVNHEK 21 0 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 ;;;;;; ;;;;;; 254.82 1.77E-63 55474100 7360.96 5900.6 7080.31 5824.18 6650.88 11275.21 8025.07 7465.11 6601.23 6054.93 FALSE FALSE TRUE 6778.332249 6410.621571 7342.712517 5800.081086 6571.5726 8936.604348 8250.231866 9741.187674 5877.091584 6265.338367 1.081878081 1.023188405 1.171957856 0.925741077 1.048877525 1.42635622 1.316805475 1.554774396 0.938032591 1 12.61317671 -5.265156404 8.57565951 1.040365564 1.421440133 0.82408433 0.085666648 0.031716665 30.84212912 0.010678046 0.025274359 5.43E-06 5.265156404 0.381074569 VIKDFMIQGGDFTR ddPTM_HeLa_Curcumin_4h_R1 2 VIKDFMIQGGDFTR 14 1 P23284 P23284 PPIB Peptidyl-prolyl cis-trans isomerase B 0 0 ; ; 86.262 0.011543 18586400 4860 4098.2 4646 4836.9 4434.6 6086 4949.8 4701.2 4676.5 4435.4 FALSE FALSE TRUE 4475.325872 4452.430147 4818.184847 4816.886189 4381.720291 4823.694997 5088.678066 6134.574238 4163.49965 4589.52982 0.975116417 0.97012773 1.049821014 1.049538053 0.954720955 1.051021605 1.108758035 1.336645469 0.907173461 1 12.16413065 -3.789064507 1.068524588 0.993019204 1.919520547 0.866601197 0.041425408 0.816486398 0.369929975 0.004813713 1.093564028 0.000162531 3.789064507 0.926501343 VIKPGGPYVGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 VIKPGGPYVGKR 12 2 O00472 O00472 ELL2 RNA polymerase II elongation factor ELL2 0 1 ; VIKPGGPYVGK(1)R;VIKPGGPYVGK(1)R 92.611 0.0038866 23300000 8467.4 8443.4 10100.9 8847.7 6846 9266 5423.2 3720.1 8802 7668.1 FALSE TRUE FALSE 7797.196355 9173.209873 10475.24824 8811.090562 6764.365921 7344.127151 5575.360396 4854.341365 7836.442622 7934.565904 0.9826872 1.156107339 1.320204327 1.110469138 0.852518714 0.925586508 0.70266735 0.611796716 0.98763344 1 12.95393558 -4.805204209 1.282153137 1.034786418 0.578511351 0.662108754 0.115334733 0.359727724 0.892797313 0.019579727 0.165991212 1.57E-05 4.805204209 -0.456275067 VILAS(ph)PETSSAK ddPTM_HeLa_Curcumin_4h_R1 1 VILASPETSSAK 12 0 C9JKS0;P49116;P49116-2 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 0 VILAS(0.759)PET(0.214)S(0.013)S(0.014)AK 85.672 0.019264 17059000 2187.7 2066.5 1839.7 2453.6 2294 3476.5 2888.4 1696 2825 2167.3 TRUE FALSE FALSE 2014.541237 2245.119052 1907.8809 2443.447653 2266.645548 2755.434712 2969.44073 2213.102593 2515.104568 2242.613514 0.898300677 1.00111724 0.850739946 1.089553612 1.010716084 1.228671233 1.324098295 0.986840835 1.121506025 1 11.1309653 -5.614573221 1.721459195 0.950777715 1.189501619 0.319416516 0.112770362 0.209421803 1.241148051 0.014390661 0.036897471 2.43E-06 5.614573221 0.238723905 VILASPET(ph)SSAK ddPTM_HeLa_Curcumin_4h_R1 1 VILASPETSSAK 12 0 C9JKS0;P49116;P49116-2 C9JKS0 NR2C2 Nuclear receptor subfamily 2 group C member 2 1 0 VILAS(0.029)PET(0.812)S(0.04)S(0.119)AK 139.76 0.0035583 18325000 5259.7 3581.9 4392.2 4813.8 4985.2 6018.8 4843.7 3023.2 4709.8 4183 TRUE FALSE FALSE 4843.389195 3891.503475 4554.978796 4793.881771 4925.754746 4770.433034 4979.601186 3944.959763 4193.146723 4328.358939 1.118989729 0.899071341 1.052356993 1.107551809 1.138019008 1.102134343 1.15045939 0.911421585 0.968761321 1 12.07960443 -6.370623331 6.606684852 1.042847636 1.089790141 0.092335938 0.084922814 0.583170646 30.98331385 0.013114819 0.02008348 4.26E-07 6.370623331 0.046942505 VILHLKEDQTEYLEER ddPTM_HeLa_Curcumin_4h_R1 4 VILHLKEDQTEYLEER 16 1 P08238;Q58FF7;Q58FF6;P07900;P07900-2;G3V2J8 P08238;P07900 HSP90AB1;HSP90AB3P;HSP90AB4P;HSP90AA1 Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-alpha 0 0 ;;; ;;; 143.58 0.0001754 148630000 10795.65 8158.93 8606.45 9102.49 7957.87 11729.51 9416.99 8896.86 11166.27 9173.79 FALSE FALSE TRUE 9941.162911 8864.151554 8925.412608 9064.826308 7862.977598 9296.677407 9681.205395 11609.47166 9941.358118 9492.57852 1.047256327 0.933798076 0.940251649 0.954938249 0.82832895 0.979362708 1.019870984 1.22300507 1.047276891 1 13.21258431 -4.264260416 3.472565407 0.989772681 1.251051917 0.579407818 0.063013439 0.19491048 4.026572728 0.009921405 0.132964034 5.44E-05 4.264260416 0.261279237 VINAAHSFYNGTTTLPISDEDRT(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 VINAAHSFYNGTTTLPISDEDRTPR 25 1 P49915-2;P49915 P49915-2 GMPS GMP synthase [glutamine-hydrolyzing] 1 0 VINAAHSFYNGTTTLPIS(0.061)DEDRT(0.939)PR;VINAAHSFYNGTTTLPIS(0.024)DEDRT(0.976)PR ; 121.59 2.74E-08 62248000 2395.7 1979.37 2026.22 2577.1 2364.98 5037 4133.2 2225.74 2906.2 2272.1 TRUE FALSE FALSE 2206.077817 2150.457923 2101.313496 2566.436643 2336.779158 3992.269421 4249.166468 2904.35788 2587.397131 2351.055306 0.938335143 0.914677727 0.893774592 1.091610494 0.99392777 1.698075503 1.807344326 1.23534222 1.100525847 1 11.19909276 -5.268293064 24.017388 0.970616654 1.602963062 0.760325439 0.151314851 87.86008977 307889.466 0.01915104 0.043774713 5.39E-06 5.268293064 0.632346408 VINEEYK ddPTM_HeLa_Curcumin_4h_R1 2 VINEEYK 7 0 E9PC52;Q16576;Q16576-2;C9JAJ9;Q09028-3;Q09028;Q09028-2;E9PNS2;E9PIC4;E9PNS6 E9PC52;Q09028-3 RBBP7;RBBP4 Histone-binding protein RBBP7;Histone-binding protein RBBP4 0 0 ; ; 128.1 0.0087046 12867400 9097.9 5865.9 6840.2 6608.8 7661.1 8511.5 7070.4 7234.7 7822.3 7541.5 FALSE FALSE TRUE 8377.791615 6372.922258 7093.703829 6581.454537 7569.746386 6746.118956 7268.776395 9440.526726 6964.21326 7803.566564 1.073584949 0.816667892 0.909033552 0.843390581 0.970036755 0.864491755 0.931468494 1.209770769 0.892439784 1 12.92991793 -7.291389763 24.83519053 1.03474845 0.928961532 0 0.113137312 785.038501 650960.645 0.017377687 0.019873646 5.11E-08 7.291389763 -0.105786918 VIPAKS(ph)PPPPTHSTQLGAPSR ddPTM_HeLa_Curcumin_4h_R1 1 VIPAKSPPPPTHSTQLGAPSR 21 1 Q14814-4;Q14814;Q14814-6;Q14814-3;Q14814-5;Q14814-2 Q14814-4 MEF2D Myocyte-specific enhancer factor 2D 1 0 VIPAKS(0.987)PPPPT(0.003)HS(0.006)T(0.002)QLGAPS(0.001)R 60.621 0.0042028 27922000 1656.5 1523.7 1714.3 1390.3 2140.4 3232.7 1914 1136.4 2114.8 1671.6 TRUE FALSE FALSE 1525.386277 1655.401839 1777.833466 1384.547307 2114.877128 2562.20158 1967.701689 1482.883129 1882.811731 1729.687976 0.881885229 0.95705229 1.027834784 0.800460734 1.222692854 1.481308546 1.137605 0.857312504 1.088526808 1 10.75629609 -5.744691644 24.98301214 0.941976344 1.193976525 0.296927392 0.159995359 196.4654225 293070.6702 0.022302195 0.044507006 1.80E-06 5.744691644 0.25200018 VIPELNGK ddPTM_HeLa_Curcumin_4h_R1 2 VIPELNGK 8 0 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 ; ; 110.81 0.0060534 143015000 15020.1 11745.7 12195.9 12736.6 13077 16358.9 13658 13236.4 12407.2 12740.8 FALSE FALSE TRUE 13831.24324 12760.94597 12647.89078 12683.89932 12921.06532 12965.87974 14041.20672 17272.11743 11046.1612 13183.54185 1.049129543 0.967945194 0.959369715 0.96210104 0.98009059 0.983489861 1.065055725 1.31012725 0.837875081 1 13.68645039 -4.27355384 2.895715134 1.005725965 1.358654566 0.721903417 0.060717561 0.105345428 1.262944562 0.005356768 0.08542264 5.33E-05 4.27355384 0.352928601 VIQCFAETGQVQK ddPTM_HeLa_Curcumin_4h_R1 1 VIQCFAETGQVQK 13 0 A0A087WVQ6;Q00610-2;Q00610 A0A087WVQ6 CLTC Clathrin heavy chain;Clathrin heavy chain 1 0 0 193.23 2.53E-13 1546900 241.91 251.84 331.48 276.54 190.74 311.36 266.11 321.98 405.06 277.6 FALSE FALSE TRUE 222.7625682 273.6079274 343.7649404 275.3957508 188.4655501 246.7804262 273.5763304 420.1502198 360.6259314 287.2465793 0.775509908 0.952519358 1.19675904 0.95874336 0.656110685 0.859123986 0.952409359 1.462681369 1.255457706 1 8.166145902 -4.263441779 4.172930873 0.903421529 1.507011035 0.405967486 0.174446724 0.125856468 4.860300682 0.020643644 0.225868988 5.45E-05 4.263441779 0.603589505 EIPSATQS(ph)PISKK ddPTM_HeLa_Curcumin_4h_R1 2 EIPSATQSPISKK 13 1 Q9BQG0;Q9BQG0-2;I3L1L3 Q9BQG0 MYBBP1A Myb-binding protein 1A 1 0 EIPS(0.002)AT(0.03)QS(0.634)PIS(0.334)KK;EIPSATQS(0.791)PIS(0.209)KK ; 214.89 2.99E-13 143164000 11108.1 9483.4 10217.1 10867.6 8477.4 12833.3 8001.6 3885.5 11329.8 10023.4 TRUE FALSE FALSE 10228.88216 10303.10284 10595.75471 10822.63275 8376.312542 10171.52892 8226.103361 5070.171063 10086.94929 10371.7124 0.986228866 0.993384934 1.021601284 1.043475979 0.807611339 0.98069909 0.793128756 0.488846091 0.972544252 1 13.34036649 -3.994410297 1.054112091 0.992210062 1.72E-15 0.863017922 0.059855307 0.66439966 0.400763229 0.008361907 0.84148453 0.000101295 3.994410297 -0.992210062 down VISELNGK ddPTM_HeLa_Curcumin_4h_R1 2 VISELNGK 8 0 P05387 P05387 RPLP2 60S acidic ribosomal protein P2 0 0 ; ; 138.83 0.00080797 33831000 11774.7 9284.3 9603 10651.9 10347.9 12781.9 10656.2 9705.7 10225.2 9634.7 FALSE FALSE TRUE 10842.72007 10086.79352 9958.895628 10607.82526 10224.50805 10130.78986 10955.18429 12664.92325 9103.521142 9969.505108 1.087588597 1.011764718 0.998935807 1.064027266 1.025578295 1.016177809 1.09886942 1.270366293 0.913136715 1 13.28330617 -4.301371619 2.586580769 1.036270647 1.307896229 0.715867295 0.047551985 0.142757274 1.29321249 0.005046218 0.080563813 5.00E-05 4.301371619 0.271625581 VISFIENTS(ph)TPVDR ddPTM_HeLa_Curcumin_4h_R1 1 VISFIENTSTPVDR 14 0 E9PGE5;Q9NUY8-2;Q9NUY8 E9PGE5 TBC1D23 TBC1 domain family member 23 1 0 VISFIENT(0.039)S(0.48)T(0.48)PVDR 196.84 2.52E-06 9457100 2180.3 1851.8 2329.8 2126.2 1993.9 3914.9 3913 1483.7 2202.5 1689 TRUE FALSE FALSE 2007.726954 2011.861341 2416.144438 2117.402348 1970.124045 3102.90561 4022.788249 1936.0733 1960.89126 1747.692624 1.148787222 1.151152847 1.38247676 1.211541617 1.127271476 1.775429825 2.301771028 1.107788219 1.121988634 1 10.77123576 -5.261453307 7.342803959 1.11584752 1.787282155 0.439317578 0.286788794 0.069482056 30.2723125 0.037815645 0.090718984 5.48E-06 5.261453307 0.671434636 VISFIENTST(ph)PVDR ddPTM_HeLa_Curcumin_4h_R1 2 VISFIENTSTPVDR 14 0 E9PGE5;Q9NUY8-2;Q9NUY8 E9PGE5 TBC1D23 TBC1 domain family member 23 1 0 VISFIENT(0.001)S(0.017)T(0.982)PVDR;VISFIENT(0.005)S(0.026)T(0.969)PVDR ; 220.97 1.04E-13 11201600 2770.3 2199.54 2287.93 2564.2 2861.4 4030.8 3972.4 1713.63 2696.3 2092.41 TRUE FALSE FALSE 2551.027832 2389.658437 2372.722698 2553.59002 2827.279674 3194.766644 4083.854853 2236.107898 2400.522636 2165.121092 1.178237948 1.103706599 1.095884525 1.17942134 1.305829815 1.475560261 1.886201593 1.03278653 1.108724424 1 11.080232 -5.610966185 1.953803899 1.090362059 1.504454191 0.394803472 0.197095657 0.213946525 1.640098692 0.027848789 0.06804326 2.45E-06 5.610966185 0.414092132 VISGTTLGYLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 VISGTTLGYLSPK 13 0 H0YBY0;E7EPX0;E7EVJ4;Q9NUL3-4;Q9NUL3-6;Q9NUL3-8;Q9NUL3-3;Q9NUL3-7;Q9NUL3-2;Q9NUL3;E5RJ67;E5RJN7 H0YBY0 STAU2 Double-stranded RNA-binding protein Staufen homolog 2 1 0 VISGTTLGYLS(1)PK;VISGT(0.003)T(0.184)LGYLS(0.813)PK ; 131.35 0.0015618 61857000 3970.8 3151.7 4102.3 3492.6 3430.6 7111 6653.7 5000.7 4197 3696.3 TRUE FALSE FALSE 3656.50699 3424.118904 4254.334847 3478.148547 3389.692336 5636.098443 6840.384914 6525.39041 3736.5996 3824.74615 0.956012987 0.895253899 1.112318225 0.909380233 0.886252892 1.473587585 1.788454618 1.706097648 0.976953621 1 11.90114828 -5.087449493 3.294479185 0.9719992 1.737529087 0.956273735 0.069392929 0.032896001 0.678229701 0.009734034 0.028809399 8.18E-06 5.087449493 0.765529886 VISPS(ph)EDR ddPTM_HeLa_Curcumin_4h_R1 1 VISPSEDR 8 0 P17252 P17252 PRKCA Protein kinase C alpha type 1 0 VIS(0.25)PS(0.75)EDR 96.034 0.017374 51464000 5030.3 3324.7 4145.7 4598.1 4163.3 5755.4 4402.4 3471.5 4855.1 4227.6 TRUE FALSE FALSE 4632.146447 3612.072253 4299.343289 4579.074281 4113.655367 4561.665163 4525.919496 4529.944369 4322.507677 4374.508785 1.058895221 0.825709224 0.982817386 1.046763078 0.940369666 1.042783404 1.034612048 1.035532123 0.988112698 1 12.09490531 -3.152759123 13.61073999 1.010295775 1.008679225 0 0.068037034 0 0 0.00903472 0 0.000703462 3.152759123 -0.001616549 VITEEEK(ac)NFK ddPTM_HeLa_Curcumin_4h_R1 1 VITEEEKNFK 10 1 P26373;P26373-2;J3KS98;H3BUK8 P26373 RPL13 60S ribosomal protein L13 0 1 VITEEEK(1)NFK 186.41 3.25E-16 3085900 1358.9 1519.2 1140.7 1206 1626.2 2442.2 1787.7 1863.9 3053.7 1110.6 FALSE TRUE FALSE 1251.341631 1650.512879 1182.975345 1201.009892 1606.808627 1935.660191 1837.858051 2432.19453 2718.71675 1149.193267 1.088887019 1.436236119 1.029396342 1.045089565 1.398205744 1.684364367 1.599259326 2.116436459 2.365761119 1 10.16640573 -1 0.341552357 1.022181902 13.1640852 0.01602679 0.44689109 14.18969046 0.178870233 0.043518459 111.5265517 0.1 1 12.1419033 VIWVKTPKPGY(ph)PS(ph)S(ph)EEPS(ph)S(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 VIWVKTPKPGYPSSEEPSSK 20 2 H0YCX2;Q96PV7-2;Q96PV7-3;Q96PV7 H0YCX2 FAM193B Protein FAM193B 5 0 VIWVKTPKPGY(1)PS(1)S(1)EEPS(1)S(1)K 45.735 0.015996 29143000 0 0 0 0 0 117.43 0 0 0 0 TRUE FALSE FALSE 0 0 0 0 0 93.07369429 0 0 0 0 0 VK(ac)LQEMEGTVK ddPTM_HeLa_Curcumin_4h_R1 2 VKLQEMEGTVK 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 1 ; VK(1)LQEMEGTVK;VK(1)LQEMEGTVK 188.96 6.07E-13 9160000 3486.1 3107.9 3104.1 3619.1 4416.7 3218.5 2885.6 2480.7 5075.1 3409 FALSE TRUE FALSE 3210.171506 3376.533027 3219.140677 3604.125123 4364.033737 2550.94682 2966.56217 3237.05401 4518.374227 3527.462496 0.910051208 0.95721302 0.912593877 1.021733081 1.2371595 0.723167666 0.840990421 0.917672127 1.28091347 1 11.78441503 VKAEPAK(ac)IEAFR ddPTM_HeLa_Curcumin_4h_R1 2 VKAEPAKIEAFR 12 2 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 1 ; VKAEPAK(1)IEAFR;VKAEPAK(1)IEAFR 93.839 0.0035945 6863000 2556 2720.3 2599.9 2183.2 3013.3 5638.4 4267.8 3795.8 5671.7 2972.9 FALSE TRUE FALSE 2353.689903 2955.430611 2696.254581 2174.166497 2977.368366 4468.932282 4387.542982 4953.121946 5049.5287 3076.208054 0.765127021 0.960738207 0.876486419 0.706768352 0.967869635 1.452740583 1.426282912 1.610138801 1.641478278 1 11.58693737 -5.277010773 3.605460523 0.878471691 1.502862351 0.412943671 0.257707632 0.058749667 1.65778939 0.015841953 0.04029589 5.28E-06 5.277010773 0.62439066 VKAPVHFVEPLS(ph)PTGVAGHR ddPTM_HeLa_Curcumin_4h_R1 2 VKAPVHFVEPLSPTGVAGHR 20 1 Q5T5Y3-2;Q5T5Y3;Q5T5Y3-3 Q5T5Y3-2 CAMSAP1 Calmodulin-regulated spectrin-associated protein 1 1 0 VKAPVHFVEPLS(0.843)PT(0.157)GVAGHR;VKAPVHFVEPLS(0.964)PT(0.036)GVAGHR ; 95.344 0.00031299 99556000 8262.7 6453.4 6668.6 6786.6 6808.7 9532.2 7618.4 7996.3 8574.3 7814.6 TRUE FALSE FALSE 7608.698576 7011.20314 6915.744182 6758.518847 6727.510699 7555.11427 7832.1518 10434.33506 7633.720742 8086.156768 0.940953632 0.86706248 0.855257248 0.835813482 0.831978762 0.93432696 0.968587677 1.290394851 0.944048076 1 12.98123846 -1.338858709 12.44477794 0.952819532 1.17999169 0 0.127340889 0 0 0.016546101 0 0.045829096 1.338858709 0.227172158 VKAQT(ph)PPGPSLSGSK ddPTM_HeLa_Curcumin_4h_R1 1 VKAQTPPGPSLSGSK 15 1 Q9UQ35;Q9UQ35-2;I3L4D8 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 VKAQT(0.985)PPGPS(0.006)LS(0.009)GSK 135.47 0.0059567 54129000 6376.4 4624.3 4982.7 5569.3 5720.9 10165 9428 8990.4 6664.9 5785.8 TRUE FALSE FALSE 5871.701212 5024.003887 5167.363245 5546.255712 5652.682004 8056.664417 9692.524306 11731.53157 5933.777145 5986.856119 0.980765379 0.839172311 0.863117994 0.926405379 0.944182037 1.345725412 1.618967303 1.95954794 0.991134082 1 12.54758288 -4.765703765 1.492364382 0.95932438 1.979363978 0.962669154 0.068614994 0.078372524 0.280821625 0.011487303 0.08938092 1.72E-05 4.765703765 1.020039598 VKAQTPPGPSLSGS(ph)KS(ph)PCPQEK ddPTM_HeLa_Curcumin_4h_R1 1 VKAQTPPGPSLSGSKSPCPQEK 22 2 Q9UQ35;Q9UQ35-2 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 VKAQT(0.222)PPGPS(0.228)LS(0.171)GS(0.588)KS(0.792)PCPQEK 62.617 0.0051525 173030000 3926.2 3018.9 2910.5 3603.4 2671.2 3494.5 2737.3 1899.3 3865.1 3407.3 TRUE FALSE FALSE 3615.437127 3279.840264 3018.36569 3588.490086 2639.347685 2769.701309 2814.101271 2478.387827 3441.1082 3525.703421 1.025451292 0.930265502 0.856103117 1.017808266 0.748601731 0.785574105 0.798167326 0.70294847 0.976006144 1 11.78369541 -5.812048836 0.612978813 1.01387728 0.713815306 0.70757729 0.061874086 0.348258232 0.221932919 0.012508234 0.052692654 1.54E-06 5.812048836 -0.300061974 VKEDDLDVVLS(ph)PQRR ddPTM_HeLa_Curcumin_4h_R1 1 VKEDDLDVVLSPQRR 15 2 B1AKL4;Q9NRA8;Q9NRA8-3;B1AKL5 B1AKL4 EIF4ENIF1 Eukaryotic translation initiation factor 4E transporter 1 0 VKEDDLDVVLS(1)PQRR 111.65 0.0014848 11417000 3945 3168.6 3714.1 3211.5 3156.1 5328.4 4526.4 1303.5 4347.8 2715.3 TRUE FALSE FALSE 3632.749087 3442.479665 3851.747813 3198.211664 3118.465569 4223.229777 4653.398602 1700.931149 3870.857218 2809.656473 1.292951335 1.225231518 1.370896353 1.138292775 1.109909912 1.503112504 1.656216212 0.605387586 1.377697685 1 11.45617803 -9.271070249 0.834464603 0.98745232 1.259400254 0 0.288496996 1.17780991 1.364631017 0.210681057 0.047955941 5.36E-10 9.271070249 0.271947934 VKEDPDGEHAR ddPTM_HeLa_Curcumin_4h_R1 3 VKEDPDGEHAR 11 1 A0A087X0X3;P52272-2;P52272;M0R2T0;M0QYQ7;M0R0N3;M0R019 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 0 ;; ;; 95.618 0.0063563 10292200 11578.8 15358.5 10377.1 8953.7 9488.9 13045.7 9019 7792.4 9294.5 11724.2 FALSE FALSE TRUE 10662.32576 16686.0203 10761.68445 8916.651962 9375.751065 10339.87476 9272.048867 10168.26689 8274.916604 12131.61508 0.878887575 1.375416233 0.887077639 0.734992984 0.772836181 0.85230818 0.764288086 0.83816267 0.682095216 1 13.56648401 -6.523245729 24.99998604 0.98115996 0.794963345 0.234791646 0.163056419 12.41409751 845658.0555 0.021727196 0.030898165 3.00E-07 6.523245729 -0.186196616 VKEDPDGEHARR ddPTM_HeLa_Curcumin_4h_R1 1 VKEDPDGEHARR 12 2 A0A087X0X3;P52272-2;P52272;M0R2T0;M0QYQ7;M0R0N3;M0R019 A0A087X0X3 HNRNPM Heterogeneous nuclear ribonucleoprotein M 0 0 60.691 0.019426 2462900 1137.4 1205.6 965.47 848.15 550.11 1014.8 850.93 525.53 901.45 788.05 FALSE FALSE TRUE 1047.37359 1309.806692 1001.251168 844.64058 543.5502975 804.3190408 874.8048056 685.7616778 802.5631903 815.4346788 1.284435917 1.606268075 1.227874155 1.035816359 0.666577363 0.986368451 1.072807949 0.840976838 0.984215181 1 9.671425503 -6.002134978 24.432935 1.184613747 0.90386011 0.394938221 0.18959919 63.55214064 727323.5187 0.031151945 0.055798392 9.95E-07 6.002134978 -0.280753637 VKEEPPS(ph)PPQS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 VKEEPPSPPQSPR 13 1 E9PMQ6;Q00613-2;Q00613 E9PMQ6 HSF1 Heat shock factor protein 1 2 0 VKEEPPS(1)PPQS(1)PR 143.28 0.0033891 8195500 4672.1 3874.8 4196.8 3795.4 3807.4 4926 3664.1 3806.9 3682.4 3554.7 TRUE FALSE FALSE 4302.298355 4209.720446 4352.3371 3779.69564 3761.999242 3904.292073 3766.904785 4967.606285 3278.449933 3678.22556 1.169666809 1.144497633 1.183270854 1.027586693 1.022775569 1.061460753 1.02410924 1.350544224 0.891312911 1 11.84479424 -9.475699851 1.229872057 1.000343487 1.119619182 0.291463857 0.102051177 0.64439984 1.751724555 0.064126546 0.015928829 3.34E-10 9.475699851 0.119275695 HAPS(ph)PEPAVQGTGVAGVPEESGDAAAIPAK ddPTM_HeLa_Curcumin_4h_R1 3 HAPSPEPAVQGTGVAGVPEESGDAAAIPAK 30 0 P13051 P13051 UNG Uracil-DNA glycosylase 1 0 HAPS(0.999)PEPAVQGT(0.001)GVAGVPEESGDAAAIPAK;HAPS(0.999)PEPAVQGT(0.001)GVAGVPEESGDAAAIPAK;HAPS(0.988)PEPAVQGT(0.01)GVAGVPEES(0.002)GDAAAIPAK ;; 76.519 1.93E-05 633988900 12139.6 10428.1 11002.3 11478.6 10521.4 12927.3 10018.7 4181.66 13269.3 11412.8 TRUE FALSE FALSE 11178.73785 11329.4585 11410.05492 11431.10459 10395.93918 10246.03226 10299.79776 5456.628884 11813.69099 11809.39395 0.946597082 0.959359857 0.966184629 0.967967081 0.880310981 0.867617111 0.872169885 0.462058333 1.000363866 1 13.52764731 -3.989197135 1.254310461 0.965018996 1.14E-31 0.924086255 0.041619049 0.491003187 0.416607271 0.006352046 0.717080114 0.000102519 3.989197135 -0.965018996 down VKEGMNIVEAMER ddPTM_HeLa_Curcumin_4h_R1 4 VKEGMNIVEAMER 13 1 P62937;P62937-2 P62937 PPIA "Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed" 0 0 ;;; ;;; 124.42 0.0018104 276160400 8198.46 6722.72 7345.19 7256.75 6845.67 9769.98 8017.06 7784.54 7952.79 7910.16 FALSE FALSE TRUE 7549.54324 7303.801961 7617.409203 7226.723491 6764.039856 7743.576018 8241.997127 10158.01041 7080.388834 8185.037471 0.922359032 0.8923358 0.930650499 0.882918804 0.826390824 0.946064822 1.006958998 1.241046293 0.865040491 1 12.99877331 -4.264883366 2.444392834 0.938953778 1.30835617 0.773632118 0.052532299 0.225914071 1.646996992 0.008327718 0.173776079 5.43E-05 4.264883366 0.369402393 VKEGNGTSNSTLSGPGLDSKPGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 VKEGNGTSNSTLSGPGLDSKPGKR 24 3 Q15648 Q15648 MED1 Mediator of RNA polymerase II transcription subunit 1 0 1 ; VKEGNGTSNSTLSGPGLDSK(0.035)PGK(0.965)R;VKEGNGTSNSTLSGPGLDSK(0.056)PGK(0.944)R 161.59 2.10E-07 8399600 2541.73 1868.47 2237.29 2004.56 1926.83 2638.3 1369 1285.01 2357.1 1890.25 FALSE TRUE FALSE 2340.549388 2029.972221 2320.205936 1996.265662 1903.853811 2091.08684 1407.410456 1676.803634 2098.532027 1955.936047 1.196639017 1.037852042 1.186238139 1.020619087 0.973372219 1.069097757 0.719558524 0.857289601 1.072904214 1 10.93364348 -4.930395926 1.262255261 1.092127132 0.7669472 0.587371086 0.086953512 0.32912189 0.841095914 0.014686778 0.100919604 1.17E-05 4.930395926 -0.325179933 VKELQAEQEDR ddPTM_HeLa_Curcumin_4h_R1 1 VKELQAEQEDR 11 1 Q00341;Q00341-2;A0A024R4E5;H0Y394 Q00341 HDLBP Vigilin 0 0 100.09 0.0095181 8059200 3343.3 2595.4 3172.9 3004.6 3205 3735.2 2753.9 2618.4 3477.5 3075.4 FALSE FALSE TRUE 3078.674277 2819.734811 3290.490465 2992.167761 3166.782468 2960.477416 2831.167022 3416.738106 3096.02695 3182.269921 0.967445991 0.886076568 1.034007343 0.940262088 0.995133206 0.930303679 0.889669039 1.07367954 0.972898914 1 11.6358405 -8.710934412 0.995980186 0.997024127 0.961727714 0.013835475 0.056471983 1.058189658 2.10348158 0.020761902 0.010158808 1.95E-09 8.710934412 -0.035296413 VKEPS(ph)VQEATSTSDILK ddPTM_HeLa_Curcumin_4h_R1 1 VKEPSVQEATSTSDILK 17 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 VKEPS(0.999)VQEATSTSDILK 96.881 0.0012112 19166000 4393.2 4112.1 4626.5 4142 4394 5656.5 4921.6 3641.3 5396 3573.5 TRUE FALSE FALSE 4045.473584 4467.531601 4797.96216 4124.861501 4341.60442 4483.278138 5059.68685 4751.515608 4804.0723 3697.678859 1.09405758 1.208198919 1.297560535 1.115527243 1.174143182 1.212457412 1.368341341 1.284999533 1.299212961 1 11.85240422 -1.433327607 0.075678472 0.745335591 2.206991048 0 0.115378004 70.89873186 0.431476583 1.477229008 11.06927811 0.036869937 1.433327607 1.461655457 VKEPSVQEAT(ph)STSDILK ddPTM_HeLa_Curcumin_4h_R1 1 VKEPSVQEATSTSDILK 17 1 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 VKEPS(0.46)VQEAT(0.467)S(0.048)T(0.018)S(0.007)DILK 85.576 0.0053636 29874000 4099.2 3435.2 4288.5 3573.8 3887.5 4732.5 3609.7 3017.5 3891.5 3406.2 TRUE FALSE FALSE 3774.743995 3732.123381 4447.435583 3559.012563 3841.144102 3750.926154 3710.978467 3937.521859 3464.612186 3524.565196 1.070981464 1.058889018 1.261839499 1.009773508 1.089820698 1.064223796 1.052889721 1.117165278 0.982989956 1 11.78322958 -8.53801685 0.803771944 1.005531 1.091215724 0.273055647 0.063781286 0.633958001 0.841016444 0.027369795 0.013360744 2.90E-09 8.53801685 0.085684724 VKESSIIAPAPAEDVDT(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 3 VKESSIIAPAPAEDVDTPPR 20 1 Q15910-5;Q15910-3;Q15910-4;Q15910;Q15910-2 Q15910-5 EZH2 Histone-lysine N-methyltransferase EZH2 1 0 VKESSIIAPAPAEDVDT(1)PPR;VKESSIIAPAPAEDVDT(1)PPR;VKESSIIAPAPAEDVDT(1)PPR ;; 133.98 7.33E-05 244774000 11326.4 9666.2 10973 10595.5 10451.5 12536.4 9911.7 8341.6 11859.8 9993.8 TRUE FALSE FALSE 10429.90349 10501.70326 11379.66903 10551.65863 10326.87269 9936.209326 10189.79563 10884.91544 10558.80961 10341.08381 1.008589011 1.015532168 1.100432918 1.020362935 0.998625761 0.960847964 0.985370181 1.052589423 1.021054447 1 13.33609978 -4.240138112 23.24475339 1.008231996 1.052589541 0.099977027 0.034342335 3439.171418 3752803.681 0.00487135 0.263266933 5.75E-05 4.240138112 0.044357545 VKGDADVSVPK ddPTM_HeLa_Curcumin_4h_R1 1 VKGDADVSVPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 92.112 0.0088676 3138000 9146.1 7881.2 8182.8 8715.5 9389.5 10786 8380.3 8778.9 9357.7 8072 FALSE FALSE TRUE 8422.176534 8562.41581 8486.061766 8679.43757 9277.536345 8548.862017 8615.428664 11455.5462 8331.183722 8352.501399 1.008341829 1.025131922 1.015990463 1.039142307 1.110749451 1.023509199 1.031478865 1.371510838 0.997447749 1 13.0279926 -4.260746259 5.267260949 1.017859409 1.386501645 0.91342928 0.031617542 0.03369786 3.239634341 0.004812644 0.044761923 5.49E-05 4.260746259 0.368642236 VKGDMDVSVPK ddPTM_HeLa_Curcumin_4h_R1 1 VKGDMDVSVPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 132.17 1.23E-11 0 8072.6 7117.8 7553.4 7823.8 8141.3 9008.2 7505.6 7685.7 7847.4 6763.9 FALSE FALSE TRUE 7433.645192 7733.030916 7833.335649 7791.427189 8044.220315 7139.797777 7716.186936 10029.03455 6986.559853 6998.945022 1.062109385 1.104885221 1.119216628 1.113228803 1.14934755 1.020124855 1.102478575 1.432935181 0.998230424 1 12.77292176 -4.265129058 3.603504219 1.055797379 1.474532527 0.813490693 0.051277083 0.093496694 2.180579495 0.008227824 0.104651651 5.43E-05 4.265129058 0.418735148 VKGDVDISLPK ddPTM_HeLa_Curcumin_4h_R1 2 VKGDVDISLPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 86.772 0.0046645 0 8853.5 6535.2 8377.3 7926 7440.8 10970.3 8219.9 7584.4 8691.2 7717.6 FALSE FALSE TRUE 8152.736133 7100.073568 8687.770107 7893.204312 7352.07332 8694.936119 8450.528271 9896.848646 7737.797104 7985.786026 1.020905908 0.889088882 1.087904194 0.988406687 0.920644918 1.08880154 1.058196181 1.239308017 0.96894621 1 12.9632187 -3.862217992 1.160570862 1.001358745 1.578326583 0.62203369 0.05817069 1.671753093 0.985397289 0.007884451 1.460477951 0.000137335 3.862217992 0.576967838 VKGDVDVSLPK ddPTM_HeLa_Curcumin_4h_R1 1 VKGDVDVSLPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 125.54 5.15E-08 0 13409 10487 11310 11508 11775 15064 11608 11959 13664 11133 FALSE FALSE TRUE 12347.6635 11393.44955 11729.15855 11460.38295 11634.59082 11939.55659 11933.68924 15605.24405 12165.09339 11519.87092 1.0718578 0.9890258 1.018167532 0.994836055 1.009958436 1.036431456 1.035922131 1.354637057 1.056009522 1 13.49183693 -4.26090093 5.687703084 1.026211654 1.36542903 0.938557519 0.025415519 0.029198694 3.92872264 0.00429836 0.038217721 5.48E-05 4.26090093 0.339217376 VKGDVDVSVPK ddPTM_HeLa_Curcumin_4h_R1 2 VKGDVDVSVPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 99.5 0.0052661 10155300 22094 16922.1 19039.2 18807.9 20949 23700 18729.9 20412.6 21849 18316.1 FALSE FALSE TRUE 20345.23659 18384.77092 19744.8095 18730.07789 20699.19686 18784.35285 19255.41059 26636.30777 19452.21936 18952.58311 1.073480932 0.97004038 1.041800444 0.9882599 1.092157029 0.991123623 1.015978164 1.405418333 1.026362436 1 14.21010687 -4.260293134 24.97947642 1.028401943 1.405418455 0.906202181 0.03694409 21.48068053 468055.8474 0.005329111 0.044015197 5.49E-05 4.260293134 0.377016512 VKGEYDVTVPK ddPTM_HeLa_Curcumin_4h_R1 2 VKGEYDVTVPK 11 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 ; ; 113.38 0.0016706 8603300 12189.6 10480.7 11755.7 13002.5 11891.7 11983.3 9939.2 10747.6 13076.2 10640.7 FALSE FALSE TRUE 11224.7803 11386.60501 12191.37658 12948.6991 11749.89924 9497.8285 10218.0672 14024.49376 11641.77358 11010.46353 1.019464827 1.034162183 1.107253709 1.176035783 1.067157546 0.862618406 0.928032428 1.273742356 1.057337281 1 13.42658759 -7.162470585 3.188870567 1.008877741 1.058581262 0.020359389 0.109849289 0.762414049 14.7836613 0.018888721 0.023223372 6.88E-08 7.162470585 0.049703521 VKLESPTVSTLTPSS(ph)PGK ddPTM_HeLa_Curcumin_4h_R1 2 VKLESPTVSTLTPSSPGK 18 1 A0A087WTV6;A0A087WZR9;Q96C36 A0A087WTV6 PYCR2 Pyrroline-5-carboxylate reductase;Pyrroline-5-carboxylate reductase 2 1 0 VKLESPTVSTLTPS(0.244)S(0.755)PGK;VKLESPTVSTLT(0.009)PS(0.214)S(0.777)PGK ; 150.63 3.99E-05 128782000 5582.8 4708.2 5434.7 6304 6146.2 8341.9 5874.6 4959.5 6302.7 4041.3 TRUE FALSE FALSE 5140.915489 5115.155829 5636.114763 6277.915718 6072.910579 6611.695907 6039.425465 6471.628719 5611.309579 4181.734874 1.229373847 1.223213805 1.347793424 1.501270623 1.452246678 1.581089214 1.444239209 1.54759422 1.341861631 1 12.02988588 -7.136633809 0.364519374 0.993090039 1.584845892 0.552108456 0.112984878 0.216296241 0.080139792 0.036198065 0.047076097 7.30E-08 7.136633809 0.591755853 VKLPSGSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VKLPSGSKK 9 2 E9PKZ0;P62917;G3V1A1 E9PKZ0 RPL8 60S ribosomal protein L8 0 1 ; VKLPSGSK(1)K;VKLPSGSK(1)K 95.483 0.003911 0 6691.3 6177.3 5689.5 4911.3 7390.5 9321.1 7075.3 6523.6 8240.3 6167.3 FALSE TRUE FALSE 6161.676544 6711.238286 5900.357875 4890.978342 7302.373114 7387.79879 7273.813876 8512.615609 7336.359706 6381.613216 0.965535882 1.051652311 0.924587197 0.766417233 1.144283251 1.15766947 1.139808012 1.333928479 1.149608956 1 12.63970546 -5.544507905 24.93158656 0.969891092 1.194664925 0.519760936 0.103506163 111.2754904 128265.1594 0.012370799 0.024743241 2.85E-06 5.544507905 0.224773833 VKLQEMEGTVK ddPTM_HeLa_Curcumin_4h_R1 1 VKLQEMEGTVK 11 1 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 113.67 0.0016248 2803800 2181.1 1746.1 1853 1945.7 1499.9 2115.8 1668.3 1806.7 2730.5 1852.2 FALSE FALSE TRUE 2008.463634 1897.025104 1921.67381 1937.649209 1482.014672 1676.95923 1715.108008 2357.554513 2430.970981 1916.563812 1.047950306 0.989805344 1.002666229 1.011001667 0.773266542 0.874982205 0.894886983 1.230094452 1.268400752 1 10.90430632 -5.958235586 24.99996788 1.018347902 0.929614231 0.102623369 0.135544669 228.3325533 136677.7723 0.015630179 0.028332086 1.10E-06 5.958235586 -0.088733671 VKPAS(ph)PVAQPK ddPTM_HeLa_Curcumin_4h_R1 1 VKPASPVAQPK 11 1 Q96EV2;H0Y3K4 Q96EV2 RBM33 RNA-binding protein 33 1 0 VKPAS(1)PVAQPK 74.783 0.01492 817970000 11791 9191.8 9954.7 9759.5 9898.6 10768 10606 7613.6 11049 9302.6 TRUE FALSE FALSE 10857.72991 9986.298234 10323.62994 9719.117775 9780.56566 8534.59542 10903.57582 9934.951591 9836.952343 9625.864658 1.127974504 1.037444281 1.072488582 1.009687765 1.016071388 0.886631562 1.132737287 1.032110044 1.021929218 1 13.23270042 -6.255805362 22.45271004 1.060699635 1.014841903 0.067058871 0.064075557 234.1532688 933137.4841 0.010757324 0.017491786 5.55E-07 6.255805362 -0.045857732 VKPPPQIS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 VKPPPQISPSK 11 1 K7ESE9;Q9H6U6-6;Q9H6U6-2;Q9H6U6;Q9H6U6-7;Q9H6U6-3;Q9H6U6-8 K7ESE9 BCAS3 Breast carcinoma-amplified sequence 3 1 0 VKPPPQIS(0.965)PS(0.035)K 85.976 0.0094787 28122000 3400.1 2816.2 3098.4 2628.5 2762.4 3055.9 2449.7 1789.4 3285.5 2862.8 TRUE FALSE FALSE 3130.978497 3059.619779 3213.22943 2617.623963 2729.460184 2422.071893 2518.431989 2334.979823 2925.08887 2962.282087 1.056948125 1.032859022 1.084714195 0.883651147 0.921404547 0.817637153 0.850166161 0.788236824 0.987444404 1 11.53249331 -5.873821555 1.502566458 1.031737214 0.825544173 0.816839337 0.042504282 0.111759106 0.507156509 0.006471093 0.014789506 1.34E-06 5.873821555 -0.206193042 VKPPPS(ph)PTTEGPSLQPDLAPEEAAGTQRPK ddPTM_HeLa_Curcumin_4h_R1 4 VKPPPSPTTEGPSLQPDLAPEEAAGTQRPK 30 2 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 VKPPPS(0.376)PT(0.296)T(0.296)EGPS(0.031)LQPDLAPEEAAGTQRPK;VKPPPS(0.665)PT(0.162)T(0.162)EGPS(0.012)LQPDLAPEEAAGTQRPK;VKPPPS(0.325)PT(0.325)T(0.325)EGPS(0.025)LQPDLAPEEAAGTQRPK;VKPPPS(0.716)PT(0.141)T(0.141)EGPS(0.001)LQPDLAPEEAAGTQRPK ;;; 111.3 2.86E-11 834517000 9614.6 7341.2 7297.7 8030.9 7957.7 10180.8 8409.5 10522.8 9760.3 8259.5 TRUE FALSE FALSE 8853.594265 7975.740616 7568.159182 7997.670264 7862.809625 8069.187319 8645.447937 13731.15328 8689.619509 8546.51701 1.035930105 0.933215321 0.885525551 0.935781237 0.920001635 0.944149214 1.011575584 1.606637331 1.016743955 1 13.06112088 -4.261916085 5.33531943 0.985044936 1.631501807 0.936958457 0.049745514 0.033035374 3.36218859 0.008560956 0.077863839 5.47E-05 4.261916085 0.646456871 VKS(ph)PGGPGSHVR ddPTM_HeLa_Curcumin_4h_R1 2 VKSPGGPGSHVR 12 1 O75382-3;O75382-2;O75382;A0A1W2PPI7;O75382-4 O75382-3 TRIM3 Tripartite motif-containing protein 3 1 0 VKS(1)PGGPGSHVR;VKS(1)PGGPGSHVR ; 63.894 0.017222 28585000 10861.8 8931.5 9401.6 8851.5 8252.4 10228.4 8522.3 7405.7 9907 9574.5 TRUE FALSE FALSE 10002.07707 9703.499062 9750.031566 8814.874838 8153.99552 8106.914542 8761.412801 9663.663838 8820.226886 9907.213162 1.009575236 0.9794378 0.984134631 0.889743129 0.823036245 0.818284053 0.884346855 0.975416969 0.890283346 1 13.27426358 -6.271071396 3.142343014 1.002088463 0.87002613 0.385066228 0.054139057 0.109408158 2.220577011 0.006488911 0.010700465 5.36E-07 6.271071396 -0.132062333 VKVDPSHDASK ddPTM_HeLa_Curcumin_4h_R1 1 VKVDPSHDASK 11 1 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 53.569 0.020341 4976500 4154 3768 3927.7 4172.2 4789.2 5728.6 4255.9 4234.1 4747.8 4238.7 FALSE FALSE TRUE 3825.206517 4093.68913 4073.264017 4154.936542 4732.091918 4540.423785 4375.3091 5525.057599 4226.978218 4385.994509 0.8721412 0.933354823 0.928697929 0.947319139 1.078909677 1.035209637 0.997563743 1.259704632 0.96374453 1 12.09868829 -1 0.582401602 0.939950677 17.22326307 0.72395166 0.053800436 65.06984235 0.491485211 0.011517731 1345.574403 0.1 1 16.28331239 VKVEPAVDTSR ddPTM_HeLa_Curcumin_4h_R1 1 VKVEPAVDTSR 11 1 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 104.07 0.0031307 12073000 8883.4 6996.5 8225.5 7793.3 8117.7 9607.8 7448.4 7126.2 8459.6 8508 FALSE FALSE TRUE 8180.269516 7601.246284 8530.344266 7761.05339 8020.901729 7615.033978 7657.382058 9298.945575 7531.603045 8803.652367 0.929190429 0.863419632 0.968955146 0.881571996 0.911087966 0.864985765 0.86979605 1.056259969 0.855508911 1 13.10388646 -8.698864796 0.720427055 0.998713829 0.912554655 0 0.071463963 0.681420284 0.69525239 0.030611138 0.011852623 2.00E-09 8.698864796 -0.086159174 VKVEPSHDASK ddPTM_HeLa_Curcumin_4h_R1 1 VKVEPSHDASK 11 1 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 60.691 0.016396 6596800 13412 12124 13530 9011.4 15043 17306 12405 11203 9367.5 10837 FALSE FALSE TRUE 12350.42605 13171.94454 14031.4337 8974.113215 14863.62205 13716.54052 12753.05091 14618.74313 8339.908686 11213.58494 1.101380701 1.174641705 1.251288841 0.800289404 1.325501356 1.223207439 1.137285799 1.303663655 0.7437326 1 13.45295996 -1.000000217 0.078328629 0.848968907 1.89604975 0.321387804 0.157111469 197.2242003 1.139263879 2.41418548 22.52743984 0.09999995 1.000000217 1.047080842 VLADPSDDTK ddPTM_HeLa_Curcumin_4h_R1 2 VLADPSDDTK 10 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4;A0A075B730;P58107 Q15149;Q15149-3;Q15149-4;A0A075B730 PLEC;EPPK1 Plectin;Epiplakin 0 0 ; ; 131.5 0.0012496 25620000 23289 19970.3 21756 21267 22902 26989 21613 14996.5 22055 18969.5 FALSE FALSE TRUE 21445.65108 21696.44375 22562.2965 21179.00279 22628.90861 21391.17717 22219.40261 19568.86381 19635.62168 19628.68871 1.092566671 1.105343513 1.149455108 1.07898205 1.152848717 1.089791452 1.131986091 0.99695217 1.000353206 1 14.26067618 -8.865937513 0.71833589 0.999241509 1.104132304 0.46633349 0.042200619 0.459332768 0.441103666 0.026384493 0.008567713 1.36E-09 8.865937513 0.104890795 VLAET(ph)PDSFEK ddPTM_HeLa_Curcumin_4h_R1 2 VLAETPDSFEK 11 0 Q99567;J3KMX1 Q99567 NUP88 Nuclear pore complex protein Nup88 1 0 VLAET(0.897)PDS(0.103)FEK;VLAET(0.921)PDS(0.079)FEK ; 118.61 0.012699 62890000 12493.4 10861.9 10980.2 10745.7 11495.9 12638.9 9721.6 8237 11373.8 10477.6 TRUE FALSE FALSE 11504.53421 11800.75424 11387.13587 10701.23714 11358.8189 10017.44967 9994.361932 10748.42338 10126.1226 10841.69582 1.061137888 1.088460185 1.050309477 0.987044584 1.047697619 0.923974426 0.921844894 0.991396877 0.933998035 1 13.40430282 -5.263470918 24.99732504 1.033592921 0.943349346 0.372691591 0.045396362 100.7822511 1240096.61 0.005324562 0.012468621 5.45E-06 5.263470918 -0.090243575 VLAGDK(ac)NFITAEELRR ddPTM_HeLa_Curcumin_4h_R1 1 VLAGDKNFITAEELRR 16 2 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 1 VLAGDK(1)NFITAEELRR 67.846 0.010574 1209000 0 191.09 112.76 115.51 150.1 198.41 116.34 184.39 274.73 61.012 FALSE TRUE FALSE 0 207.6069681 116.9389848 115.0320502 148.3101555 157.2575295 119.6041873 240.6096622 244.5928063 63.13216246 0 3.288450134 1.8522886 1.822083162 2.349201259 2.490925755 1.894504839 3.811205775 3.87429793 1 5.980303263 -7.267750672 24.99958165 0.52777776 2.420576246 0 1.239182671 230.9673479 914880.4539 0.11352608 0.131499842 5.40E-08 7.267750672 1.892798486 VLAGDKNFITAEELR ddPTM_HeLa_Curcumin_4h_R1 2 VLAGDKNFITAEELR 15 1 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 0 ; ; 137.09 0.00050902 75458000 5108.8 3533.1 4534.8 4284.6 4933.4 6057.5 4590.7 5127 4538.9 3975.4 FALSE FALSE TRUE 4704.433089 3838.485421 4702.863677 4266.87146 4874.572427 4801.106218 4719.502687 6690.198698 4040.994026 4113.544854 1.143644534 0.933133236 1.143263011 1.037273595 1.185005293 1.167145707 1.147307943 1.626382824 0.982362942 1 12.00616646 -1.312943159 0.953293377 1.068430943 199.9999589 0.813376003 0.079314667 193.1908934 0.619798768 0.012037603 83409.01322 0.048647087 1.312943159 198.931528 VLAGDKNFITAEELRR ddPTM_HeLa_Curcumin_4h_R1 2 VLAGDKNFITAEELRR 16 2 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 0 ; ; 99.991 0.0011218 56748900 5231.2 4410.9 4011.6 4874.4 3060.9 6691.1 4271 4961.2 6422.1 5341.2 FALSE FALSE TRUE 4817.145 4792.158541 4160.273425 4854.231024 3024.400767 5303.290436 4390.832765 6473.847041 5717.611697 5526.806302 0.871596495 0.867075537 0.752744568 0.878306703 0.547223948 0.959557861 0.794461127 1.171354067 1.034523626 1 12.43223034 -8.641981928 0.75744811 0.993898465 0.842568397 0.148884127 0.149726297 0.933525011 1.074152271 0.073071863 0.031094274 2.28E-09 8.641981928 -0.151330068 VLAGETLS(ph)VNDPPDVLDR ddPTM_HeLa_Curcumin_4h_R1 1 VLAGETLSVNDPPDVLDR 18 0 Q12906;Q12906-7;Q12906-5;Q12906-4;Q12906-2;Q12906-6;Q12906-3;K7EKJ9;K7EQR9 Q12906 ILF3 Interleukin enhancer-binding factor 3 1 0 VLAGET(0.003)LS(0.997)VNDPPDVLDR 191.47 6.66E-09 6930200 2396.6 2126.3 2254.7 2262.7 2405 3546.3 2662.2 2574.7 2625.1 2254.7 TRUE FALSE FALSE 2206.906581 2310.087897 2338.261165 2253.337547 2376.321946 2810.757405 2736.894167 3359.714178 2337.133098 2333.050657 0.945931703 0.990157625 1.002233346 0.965833099 1.018547085 1.204756269 1.17309676 1.440051963 1.001749829 1 11.18800192 -3.85832582 0.668148686 0.972829213 1.975390285 0.920820785 0.041256083 0.852327084 0.182410139 0.0069592 0.733962146 0.000138572 3.85832582 1.002561072 VLAGETLSVNDPPDVLDR ddPTM_HeLa_Curcumin_4h_R1 1 VLAGETLSVNDPPDVLDR 18 0 Q12906;Q12906-7;Q12906-5;Q12906-4;Q12906-2;Q12906-6;Q12906-3;K7EKJ9;K7EQR9 Q12906 ILF3 Interleukin enhancer-binding factor 3 0 0 196.7 2.47E-08 2956200 684.02 613.97 634.51 602.58 615.77 638.21 621.77 423.64 552.17 642.58 FALSE FALSE TRUE 629.8790952 667.038831 658.0254988 600.0866836 608.4273449 505.8380519 639.2151928 552.8058858 491.5983325 664.9096072 0.947315377 1.003202276 0.98964655 0.902508668 0.91505272 0.760762134 0.96135653 0.831400058 0.739346111 1 9.377014413 -5.975908047 2.038160295 0.977965737 0.863553513 0.020631482 0.091008525 0.190201634 1.583589629 0.007519533 0.014868946 1.06E-06 5.975908047 -0.114412224 VLALPEPSPAAPTLR ddPTM_HeLa_Curcumin_4h_R1 2 VLALPEPSPAAPTLR 15 0 Q15149;Q15149-7;Q15149-8;Q15149-9;Q15149-5;Q15149-6;Q15149-3;Q15149-2;H0YDN1;Q15149-4 Q15149;Q15149-3;Q15149-4 PLEC Plectin 0 0 ; ; 153.95 0.0028126 4405400 2068.63 1734.02 2001.54 1949.61 1519.28 2092.79 1500.07 1629.89 2077.89 1985.36 FALSE FALSE TRUE 1904.895753 1883.900962 2075.718833 1941.54303 1501.163578 1658.721763 1542.157927 2126.835958 1849.950666 2054.351112 0.927249359 0.917029689 1.010401202 0.945088217 0.730723959 0.807418826 0.750678848 1.035283572 0.900503645 1 11.00446706 -5.895143752 8.006883023 0.963994707 0.823965511 0.31993117 0.083701794 0.178032335 12.32947245 0.011489192 0.020888358 1.27E-06 5.895143752 -0.140029196 VLANPGNSQVAR ddPTM_HeLa_Curcumin_4h_R1 2 VLANPGNSQVAR 12 0 Q14974;J3QR48 Q14974 KPNB1 Importin subunit beta-1 0 0 ; ; 159.34 1.42E-05 5737400 3173.2 2343 3080.9 3468.5 2504.3 3790.7 2890.3 2408.48 3378.2 2761.3 FALSE FALSE TRUE 2922.037872 2545.51848 3195.080864 3454.148266 2474.437858 3004.46609 2971.394039 3142.814465 3007.619912 2857.254969 1.022673126 0.89089651 1.118234424 1.208904457 0.866019268 1.051521871 1.039947107 1.099941902 1.052625665 1 11.48041407 -1 0.165452336 0.995735478 1.279491447 0.023575872 0.095135775 174.2676449 1.80048835 0.150803429 12.21543655 0.1 1 0.283755969 VLAPILPDNFST(ph)PTGSR ddPTM_HeLa_Curcumin_4h_R1 2 VLAPILPDNFSTPTGSR 17 0 Q9NQS7-2;Q9NQS7 Q9NQS7-2 INCENP Inner centromere protein 1 0 VLAPILPDNFS(0.203)T(0.759)PT(0.038)GS(0.001)R;VLAPILPDNFS(0.223)T(0.73)PT(0.047)GS(0.001)R ; 166.52 0.00028792 234110000 6419.2 5056.6 4750.1 6153.4 5767.6 10451.2 10674.4 2700.3 7045.3 4500.5 TRUE FALSE FALSE 5911.113546 5493.669972 4926.142885 6127.938861 5698.825137 8283.503311 10973.89494 3523.609039 6272.448216 4656.89204 1.269325871 1.17968592 1.057817712 1.315885962 1.223740015 1.778762153 2.35648472 0.756643918 1.346917249 1 12.18515172 -5.33403576 4.711090788 1.145720277 1.702560186 0.199025124 0.380211374 0.185526801 7.797021334 0.049399083 0.114795495 4.63E-06 5.33403576 0.556839909 VLATAFDTTLGGR ddPTM_HeLa_Curcumin_4h_R1 1 VLATAFDTTLGGR 13 0 P34932;A0A087WYC1;A0A087WTS8 P34932 HSPA4 Heat shock 70 kDa protein 4 0 0 110.39 0.0021246 437910 0 0 0 0 0 171.66 0 142.37 0 0 FALSE FALSE TRUE 0 0 0 0 0 136.055781 0 185.7779576 0 0 0 VLATVTK(ac)PVGGDK ddPTM_HeLa_Curcumin_4h_R1 2 VLATVTKPVGGDK 13 1 Q02878;F8VZ45;U3KQR5;F8VZA3;F8VWR1;F8VU16 Q02878 RPL6 60S ribosomal protein L6 0 1 ; VLATVTK(1)PVGGDK;VLATVTK(1)PVGGDK 155.06 0.00012589 9035400 3463.9 5124.7 3171.1 3134.9 7003.3 8587.5 6514 6562.2 8108.1 3550.2 FALSE TRUE FALSE 3189.72866 5567.656233 3288.623756 3121.928614 6919.790222 6806.355699 6696.765308 8562.984571 7218.661715 3673.569186 0.868291435 1.515598578 0.895212146 0.849835257 1.883669497 1.852790938 1.822958809 2.330971363 1.965026749 1 11.84296673 -5.737473915 8.074804939 0.975360919 1.956385756 0.45623013 0.384619109 0.060227458 16.12580961 0.032245716 0.063646511 1.83E-06 5.737473915 0.981024837 VLAVNQENEHLMEDYEK ddPTM_HeLa_Curcumin_4h_R1 2 VLAVNQENEHLMEDYEK 17 0 O43707;O43707-2;K7EJH8 O43707 ACTN4 Alpha-actinin-4 0 0 ; ; 101.01 0.001302 27944000 3967.87 2889.11 4009.59 3464.49 3900.8 5429.32 3879.81 3731.54 4288.8 2928.92 FALSE FALSE TRUE 3653.808903 3138.831795 4158.188933 3450.154858 3854.285508 4303.217831 3988.667027 4869.269368 3818.32937 3030.699752 1.205599103 1.035678903 1.372022725 1.138402066 1.271747723 1.419875997 1.316087819 1.606648552 1.25988375 1 11.56543522 -1 0.16534017 0.988596454 3.087847574 0.526928643 0.118564878 23.74840712 0.24526085 0.15229429 12.30474454 0.1 1 2.09925112 VLCLAVAVGHVK ddPTM_HeLa_Curcumin_4h_R1 2 VLCLAVAVGHVK 12 0 P62906 P62906 RPL10A 60S ribosomal protein L10a 0 0 ; ; 109.83 0.00010225 1476600 1876.06 1261.51 1638.31 1437.05 1652.94 1540.03 1637.5 1252.35 1611.95 1580.2 FALSE FALSE TRUE 1727.567871 1370.549303 1699.02721 1431.103868 1633.22977 1220.610418 1683.443843 1634.18575 1435.123118 1635.111832 1.056544169 0.838199123 1.0390893 0.87523302 0.99884897 0.746499655 1.029558841 0.999433627 0.877691109 1 10.6751736 -7.2917053 24.97411844 1.026701415 0.933454495 0 0.100123682 769.2895685 634782.2457 0.014143074 0.01617429 5.11E-08 7.2917053 -0.09324692 VLDNYLTSPLPEEVDET(ph)SAEDEGVSQRK ddPTM_HeLa_Curcumin_4h_R1 2 VLDNYLTSPLPEEVDETSAEDEGVSQRK 28 1 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 1 0 VLDNY(0.001)LT(0.013)S(0.011)PLPEEVDET(0.476)S(0.476)AEDEGVS(0.023)QRK;VLDNYLTS(0.001)PLPEEVDET(0.499)S(0.499)AEDEGVSQRK ; 84.68 2.23E-05 6993200 1991.89 1885.35 1527.83 2036.05 1386.22 2449.58 1973.46 1864.4 2382.71 2006.24 TRUE FALSE FALSE 1834.229805 2048.311253 1584.452724 2027.625365 1369.690232 1941.509496 2028.829976 2432.846977 2121.332674 2075.956691 0.883558801 0.986683037 0.763239778 0.976718529 0.659787479 0.935236031 0.977298797 1.171916056 1.021857866 1 11.01956063 -4.285851872 2.493528864 0.915729657 1.219808616 0.35546533 0.108283732 0.426316557 3.408900177 0.014755837 0.26770743 5.18E-05 4.285851872 0.30407896 VLDNYLTSPLPEEVDETS(ph)AEDEGVSQR ddPTM_HeLa_Curcumin_4h_R1 1 VLDNYLTSPLPEEVDETSAEDEGVSQR 27 0 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 1 0 VLDNYLTSPLPEEVDET(0.126)S(0.873)AEDEGVS(0.001)QR 133.72 4.43E-09 2828900 1508.5 1205.2 1194.9 1416.6 1325.7 1924.4 1678.5 1441.9 1732.8 1442.5 TRUE FALSE FALSE 1389.100633 1309.372118 1239.184045 1410.738485 1309.891893 1525.257748 1725.594193 1881.528672 1542.716175 1492.626768 0.930641647 0.877226743 0.830203553 0.945138138 0.877574972 1.021861446 1.15607882 1.26054866 1.033557892 1 10.54363775 -4.716644521 2.159650877 0.94214326 1.252603342 0.786082355 0.058524076 0.124863889 1.071478725 0.008880709 0.052188801 1.92E-05 4.716644521 0.310460082 VLDNYLTSPLPEEVDETSAEDEGVSQR ddPTM_HeLa_Curcumin_4h_R1 2 VLDNYLTSPLPEEVDETSAEDEGVSQR 27 0 O00299 O00299 CLIC1 Chloride intracellular channel protein 1 0 0 ; ; 141 3.48E-08 11116600 3200.2 2749.53 2978.9 3198.19 3286.4 4181.7 2933.92 3058.77 3420.2 3183.76 FALSE FALSE TRUE 2946.900793 2987.187122 3089.300655 3184.956737 3247.211826 3314.368283 3016.237899 3991.374892 3045.012617 3294.395423 0.894519453 0.9067482 0.937744338 0.966780343 0.985677616 1.006062678 0.915566443 1.211565213 0.924300889 1 11.68579802 -4.256664329 24.89184888 0.951001702 1.211565326 0.81434279 0.037652223 184.5366094 961935.475 0.006504577 0.070853733 5.54E-05 4.256664329 0.260563624 VLDPFTIK(ac)PLDR ddPTM_HeLa_Curcumin_4h_R1 1 VLDPFTIKPLDR 12 1 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 1 VLDPFTIK(1)PLDR 80.763 0.015693 0 0 135.53 61.005 215.6 155.86 327 174.81 123.76 170.24 184.42 FALSE TRUE FALSE 0 147.2446093 63.26589897 214.7079043 154.0014713 259.176514 179.7146981 161.4938543 151.5650979 190.8285813 0 0.771606687 0.331532617 1.12513494 0.807014705 1.358164025 0.941759861 0.846277079 0.794247365 1 7.576133456 -6.255226785 24.83083896 0.52456874 1.018999481 0.343733415 0.296522924 484.6253077 1936974.861 0.059987468 0.097841334 5.56E-07 6.255226785 0.494430742 VLDPFTIK(ac)PLDRK ddPTM_HeLa_Curcumin_4h_R1 1 VLDPFTIKPLDRK 13 2 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 1 VLDPFTIK(1)PLDRK 75.669 0.011136 800430 573.36 545.42 502.57 405.33 775.34 1224.5 1078.6 859.57 1290.4 568.45 FALSE TRUE FALSE 527.977951 592.5636745 521.1956863 403.6528519 766.0945769 970.524897 1108.862613 1121.648936 1148.846348 588.2035952 0.897610887 1.007412534 0.886080416 0.686246829 1.302430966 1.649981239 1.885168031 1.906905951 1.953144044 1 9.200171792 -5.317529823 2.161270518 0.933756544 1.87620586 0.463072253 0.339157359 0.054051434 0.486683099 0.015678096 0.045272309 4.81E-06 5.317529823 0.942449317 VLDPFTIKPLDRK ddPTM_HeLa_Curcumin_4h_R1 1 VLDPFTIKPLDRK 13 2 P29401;P29401-2;A0A0B4J1R6 P29401 TKT Transketolase 0 0 67.749 0.015009 16164000 2278.9 1994.3 2289.3 2197.4 1577.8 2609.3 2166.2 2085.4 2434 3372.9 FALSE FALSE TRUE 2098.52266 2166.678406 2374.143472 2188.307741 1558.985765 2068.101767 2226.977742 2721.22886 2166.99629 3490.108024 0.60127728 0.620805543 0.68024928 0.627002868 0.446686966 0.592560962 0.638082755 0.779697603 0.620896624 1 11.76905598 -9.215465405 0.68483943 1.036511098 0.613504176 0 0.140621231 0.343012943 0.252147105 0.085396588 0.017438579 6.09E-10 9.215465405 -0.423006922 VLDSGAPIK(ac)IPVGPETLGR ddPTM_HeLa_Curcumin_4h_R1 1 VLDSGAPIKIPVGPETLGR 19 1 P06576;H0YH81;F8W079 P06576 ATP5B "ATP synthase subunit beta, mitochondrial;ATP synthase subunit beta" 0 1 VLDSGAPIK(1)IPVGPETLGR 87.647 0.013643 414480 0 0 0 0 0 0 0 0 0 0 FALSE TRUE FALSE 0 0 0 0 0 0 0 0 0 0 0 VLDSGAPIKIPVGPETLGR ddPTM_HeLa_Curcumin_4h_R1 1 VLDSGAPIKIPVGPETLGR 19 1 P06576;H0YH81;F8W079 P06576 ATP5B "ATP synthase subunit beta, mitochondrial;ATP synthase subunit beta" 0 0 97.214 0.0037012 974650 581.65 523.01 381.1 546.39 550.12 894.55 530.8 519.44 624.38 552.54 FALSE FALSE TRUE 535.6117887 568.2166539 395.2239012 544.129183 543.5601783 709.0102463 545.6928194 677.8148648 555.8870761 571.7407239 0.936808883 0.993836245 0.691264213 0.951706185 0.95071097 1.240090511 0.954441055 1.185528399 0.972271264 1 9.159217244 -5.356104126 10.98006501 0.94725238 1.109389007 0.401854503 0.108688795 0.504218862 56.17718322 0.015130341 0.033846402 4.40E-06 5.356104126 0.162136627 VLDSVEAGDT(ph)TPPTK ddPTM_HeLa_Curcumin_4h_R1 1 VLDSVEAGDTTPPTK 15 0 Q8IZ21-3 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 0 VLDSVEAGDT(0.5)T(0.5)PPTK 198.48 1.69E-06 19792000 9422.5 7112.6 7623.7 7636.6 8345.7 9877.5 7673.3 3782.3 8843.6 7671.6 TRUE FALSE FALSE 8676.699182 7727.381451 7906.241028 7605.001773 8246.182978 7828.795158 7888.592146 4935.505858 7873.479206 7938.187529 1.09303278 0.973444054 0.995975593 0.958027477 1.038799216 0.986219478 0.993752304 0.62174216 0.991848476 1 12.95459393 -4.24106202 3.377176599 1.026227017 0.558835638 0.88500848 0.040687684 0.09454087 1.708935898 0.006909677 0.116324331 5.74E-05 4.24106202 -0.467391379 VLDSVEAGDTT(ph)PPTK ddPTM_HeLa_Curcumin_4h_R1 3 VLDSVEAGDTTPPTK 15 0 Q8IZ21-3 Q8IZ21-3 PHACTR4 Phosphatase and actin regulator 4 1 0 VLDS(0.009)VEAGDT(0.042)T(0.949)PPTK;VLDSVEAGDT(0.077)T(0.921)PPT(0.002)K;VLDS(0.003)VEAGDT(0.2)T(0.797)PPTK ;; 194.59 4.62E-06 83362000 17022.5 14593.9 15247.9 16002.6 15541.4 20083.9 15550.5 9241.2 18851.1 15821.7 TRUE FALSE FALSE 15675.15116 15855.33169 15813.00059 15936.38548 15356.07896 15918.27275 15986.80518 12058.79934 16783.18149 16371.5029 0.957465619 0.968471361 0.965885703 0.973422268 0.937976132 0.972315911 0.976501991 0.736572532 1.025146048 1 13.99889915 -4.261063539 24.98281112 0.973936213 0.73657246 0.911594824 0.022294225 5.551990426 368908.6194 0.002767971 0.021769326 5.48E-05 4.261063539 -0.237363753 VLDTSSLTQS(ph)APAS(ph)PTNK ddPTM_HeLa_Curcumin_4h_R1 1 VLDTSSLTQSAPASPTNK 18 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 2 0 VLDTSS(0.001)LT(0.048)QS(0.965)APAS(0.895)PT(0.091)NK 105.5 0.0023959 9849000 2125.9 1870 2313.3 2433.5 2286.4 2153.2 1658.3 1104.6 2650.5 2645.1 TRUE FALSE FALSE 1957.632772 2031.634467 2399.032933 2423.430822 2259.136173 1706.602048 1704.827435 1441.387455 2359.746781 2737.017028 0.715243183 0.742280536 0.876513704 0.885427747 0.825400847 0.623526281 0.622877906 0.526627142 0.862160066 1 11.41838869 -13.52287875 0.042605231 2.248683536 6.46E-13 0.53419785 0.095351494 358.3033265 1.216364949 57.81355823 17.4809417 3.00E-14 13.52287875 -2.248683536 VLDTSSLTQSAPAS(ph)PTNK ddPTM_HeLa_Curcumin_4h_R1 2 VLDTSSLTQSAPASPTNK 18 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 0 VLDTSSLTQS(0.001)APAS(0.996)PT(0.004)NK;VLDTSSLTQSAPAS(0.5)PT(0.5)NK ; 295.37 9.49E-82 44721000 8922.8 7691.4 8146 8572.9 8221.2 8994.2 6316.4 5372.4 9168.7 7866.7 TRUE FALSE FALSE 8216.550965 8356.210344 8447.897926 8537.427611 8123.167559 7128.701534 6493.621184 7010.420029 8162.916549 8140.067239 1.009395957 1.026552988 1.037816725 1.048815367 0.997923889 0.875754625 0.797735571 0.861223848 1.002807017 1 12.990825 -5.193632382 3.183171342 1.012429049 0.83055949 0.931986464 0.021589367 0.04669675 0.927832335 0.003251341 0.009088919 6.40E-06 5.193632382 -0.18186956 VLDTSSLTQSAPASPT(ph)NK ddPTM_HeLa_Curcumin_4h_R1 1 VLDTSSLTQSAPASPTNK 18 0 Q8N122-3;Q8N122;I3L436 Q8N122-3 RPTOR Regulatory-associated protein of mTOR 1 0 VLDTSSLTQSAPAS(0.099)PT(0.901)NK 222.96 4.14E-17 145570000 4683.4 3669.8 3614.2 3702.8 3734.7 4430.5 2859 2674.6 4311.7 3621.1 TRUE FALSE FALSE 4312.703948 3987.00116 3748.145431 3687.478795 3690.166142 3511.564358 2939.215845 3490.073228 3838.717297 3746.932955 1.150995761 1.06407059 1.000323592 0.98413258 0.984849792 0.937183665 0.784432463 0.931448005 1.024495859 1 11.87149445 -5.591430926 0.909504805 1.070037726 0.855718629 0.610636129 0.056226538 0.351315543 0.523468482 0.01178366 0.047080815 2.56E-06 5.591430926 -0.214319097 VLEDEEGS(ph)KDIELSDDPYDCIR ddPTM_HeLa_Curcumin_4h_R1 1 VLEDEEGSKDIELSDDPYDCIR 22 1 Q15024 Q15024 EXOSC7 Exosome complex component RRP42 1 0 VLEDEEGS(0.83)KDIELS(0.153)DDPY(0.017)DCIR 67.312 0.0012835 81494000 4729.8 4580.3 4458.5 4176.2 4645.2 5485.2 5445.9 7017.3 4765.8 4944.8 TRUE FALSE FALSE 4355.431339 4976.200723 4623.735932 4158.919991 4589.809024 4347.507689 5598.697297 9156.842466 4243.003663 5116.631432 0.851230228 0.97255407 0.903667969 0.812823837 0.897037257 0.849681621 1.094215476 1.789623229 0.829257241 1 12.3209786 -4.274861243 2.815177591 0.914898459 1.935047457 0.949531198 0.062011121 0.069689434 0.771239843 0.009753647 0.160250128 5.31E-05 4.274861243 1.020148998 VLEDEEGSKDIELSDDPYDCIR ddPTM_HeLa_Curcumin_4h_R1 1 VLEDEEGSKDIELSDDPYDCIR 22 1 Q15024 Q15024 EXOSC7 Exosome complex component RRP42 0 0 109.72 2.44E-05 5647400 3763.7 3434.9 3415.9 4121.1 3563.7 4294.2 3135.4 2739.7 4493.4 3316.6 FALSE FALSE TRUE 3465.799174 3731.79745 3542.496259 4104.04798 3521.205205 3403.534514 3223.370886 3575.021918 4000.485262 3431.851603 1.009891911 1.087400588 1.032240513 1.195869884 1.026036558 0.991748743 0.939251243 1.041718096 1.165692962 1 11.74477146 -3.897606019 19.37876131 1.021128433 3.027663912 0 0.080070441 2452.408787 477601.6889 0.00917217 6305.005675 0.000126588 3.897606019 2.00653548 VLEDSDLK ddPTM_HeLa_Curcumin_4h_R1 1 VLEDSDLK 8 0 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 0 109.01 0.0070505 6287600 6251.2 5571.5 5841.1 5596.9 5538.3 7756.9 4894 4098.2 5955.5 5205.5 FALSE FALSE TRUE 5756.410924 6053.075634 6057.576304 5573.741511 5472.25939 6148.031502 5031.312468 5347.722314 5302.19655 5386.390738 1.068695385 1.123772101 1.124607664 1.034782247 1.015941779 1.141400949 0.934078628 0.992821088 0.98436909 1 12.39510317 -4.731532676 24.99999475 1.051020298 0.963449809 0.330376474 0.054271539 204.2724984 170755.1036 0.007708966 0.028836061 1.86E-05 4.731532676 -0.087570489 VLEDSDLK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VLEDSDLKK 9 1 P11021 P11021 HSPA5 78 kDa glucose-regulated protein 0 1 ; VLEDSDLK(1)K;VLEDSDLK(1)K 130.96 6.94E-10 3416300 3389.9 4264.9 4189.1 4136.3 6291 8785.7 6293.5 4785.2 8078.5 3687 FALSE TRUE FALSE 3121.585838 4633.538952 4344.351731 4119.185087 6215.983934 6963.446785 6470.078672 6244.185452 7192.308761 3815.122976 0.818213687 1.214518898 1.138718662 1.079699164 1.629301067 1.825222104 1.695903045 1.6366931 1.885210204 1 11.89751385 -5.876901428 1.318224521 0.939007019 1.746909384 0.193653836 0.325698451 0.111002303 0.384952124 0.02293475 0.055414802 1.33E-06 5.876901428 0.807902365 VLEEANQAINPK ddPTM_HeLa_Curcumin_4h_R1 1 VLEEANQAINPK 12 0 A0A1X7SBZ2;A0A5H1ZRQ2;Q92841;Q92841-1;Q92841-3;Q92841-2 A0A1X7SBZ2 DDX17 Probable ATP-dependent RNA helicase DDX17 0 0 139.86 0.00014209 1303600 655.98 409.62 537.85 718.8 752.68 587.76 531.32 566.92 577.25 632.59 FALSE FALSE TRUE 604.0584908 445.0257276 557.7831941 715.8257961 743.7047826 465.8519506 546.2274092 739.7712982 513.9271192 654.5724554 0.922829071 0.679872371 0.852133617 1.093577632 1.136168772 0.7116889 0.834479674 1.130159529 0.785134044 1 9.354409084 -8.787536273 1.214147443 0.991183025 0.915847119 0 0.166335201 1.250118984 3.680937512 0.056054091 0.02907342 1.63E-09 8.787536273 -0.075335906 VLEEEEQRR ddPTM_HeLa_Curcumin_4h_R1 1 VLEEEEQRR 9 1 E7EX44;Q05682-3;Q05682-6;Q05682-2;Q05682;Q05682-5;Q05682-4;E9PGZ1;C9J813 E7EX44;Q05682;Q05682-5 CALD1 Caldesmon 0 0 106.2 0.015206 14669000 2460.7 2170.3 2239.7 2330.8 2568.5 2905.3 2436.9 2691.4 2764.8 2709.2 FALSE FALSE TRUE 2265.932998 2357.891061 2322.705252 2321.155767 2537.872315 2302.708031 2505.272855 3511.99547 2461.508357 2803.344498 0.808296305 0.841099288 0.82854792 0.827995192 0.90530162 0.821414575 0.893672846 1.252787687 0.878061315 1 11.45293333 -4.262090171 6.631810013 0.885227098 1.259490025 0.803369266 0.056618002 0.054845073 15.45675542 0.011216902 0.09203721 5.47E-05 4.262090171 0.374262927 VLEILGK ddPTM_HeLa_Curcumin_4h_R1 1 VLEILGK 7 0 A0A0C4DFS8;P43490 A0A0C4DFS8 NAMPT Nicotinamide phosphoribosyltransferase 0 0 110.63 0.013481 468330 779.2 482.43 646.95 883.92 695.65 899.87 541.58 592.95 732.43 595.19 FALSE FALSE TRUE 717.5254978 524.1290995 670.9265361 880.2625732 687.3548281 713.2268184 556.7752772 773.7377254 652.0842614 615.8728082 1.165054681 0.85103465 1.089391392 1.429292805 1.116066205 1.158074864 0.904042636 1.256327143 1.058796967 1 9.266488622 -11.512112 0.368666197 0.689584123 1.129068998 0.051323712 0.154878048 27.20971341 1.342664098 6.377771415 0.04915786 3.08E-12 11.512112 0.439484875 VLENAEGAR ddPTM_HeLa_Curcumin_4h_R1 1 VLENAEGAR 9 0 P38646;D6RJI2;A0A3B3ITI4;D6RA73 P38646 HSPA9 "Stress-70 protein, mitochondrial" 0 0 125.71 0.00091736 5186200 1890.5 1232.5 1734.5 1946 1714.5 2652 1897 1691.4 1983.8 1455.9 FALSE FALSE TRUE 1740.86493 1339.031808 1798.782096 1937.947968 1694.055707 2101.945306 1950.224714 2207.100074 1766.182103 1506.492417 1.155574971 0.888840723 1.194020014 1.286397426 1.124503309 1.395257807 1.294546652 1.465058867 1.172380348 1 10.5569777 -1 0.220935916 1.016357913 3.404738383 0.568496056 0.10794249 22.72826689 0.272343832 0.073152269 19.56744815 0.1 1 2.38838047 VLENIELNK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VLENIELNKK 10 1 B0QY90;B0QY89;Q9Y262-2;Q9Y262 B0QY90 EIF3L Eukaryotic translation initiation factor 3 subunit L 0 1 ; VLENIELNK(1)K;VLENIELNK(1)K 125.74 0.00069884 1969060 671.94 901.34 563.53 542.53 1488.49 1164.96 736.41 712.35 1120.8 680.72 FALSE TRUE FALSE 618.75524 979.2478133 584.4149175 540.2851546 1470.740729 923.3341642 757.0716827 929.5422357 997.8510441 704.3749693 0.878445809 1.39023653 0.829692909 0.767041957 2.088008224 1.310856013 1.074813438 1.319669602 1.416647507 1 9.460199832 VLEQLTGQTPVFS(ph)K ddPTM_HeLa_Curcumin_4h_R1 2 VLEQLTGQTPVFSK 14 0 P62913;Q5VVC8;P62913-2 P62913 RPL11 60S ribosomal protein L11 1 0 VLEQLTGQT(0.002)PVFS(0.998)K;VLEQLTGQT(0.039)PVFS(0.961)K ; 112.12 0.0026493 55844000 6885.8 4351.8 6100.3 5681.9 6496.8 8991.1 6174.4 4386.6 6930.4 6117 TRUE FALSE FALSE 6340.781664 4727.950201 6326.382484 5658.389803 6419.329903 7126.244509 6347.637046 5724.054147 6170.152459 6329.565295 1.00177206 0.746962861 0.999497152 0.893961835 1.014181797 1.12586634 1.002855133 0.904336061 0.974814568 1 12.62789071 -4.25346379 22.72621 0.98603904 0.904335917 0.031480279 0.093280035 662.600554 1887889.499 0.012718138 0.174861114 5.58E-05 4.25346379 -0.081703123 VLES(ph)PENK ddPTM_HeLa_Curcumin_4h_R1 2 VLESPENK 8 0 Q8N3D4 Q8N3D4 EHBP1L1 EH domain-binding protein 1-like protein 1 1 0 VLES(1)PENK;VLES(1)PENK ; 145.25 0.0024667 101272000 12163.3 11269.6 11868.1 12515.6 11831.5 15849.6 11130.7 8832.4 14056.7 12296.8 TRUE FALSE FALSE 11200.56197 12243.69401 12307.94223 12463.81376 11690.41709 12562.2143 11442.99749 11525.3581 12514.71518 12724.11288 0.880262701 0.962243429 0.967292756 0.979542847 0.918760875 0.987276238 0.899315936 0.905788734 0.983543237 1 13.63527746 VLETAEDIQER ddPTM_HeLa_Curcumin_4h_R1 1 VLETAEDIQER 11 0 A0A0D9SGF6;A0A0D9SF54;Q13813-3;Q13813;Q13813-2;A0A1B0GTB7;A0A0D9SFF6 A0A0D9SGF6 SPTAN1 "Spectrin alpha chain, non-erythrocytic 1" 0 0 148.56 0.0063271 8937100 1660.5 1326.2 1603.2 1432.5 1380.6 1706 1570 1473 1743.4 1424.4 FALSE FALSE TRUE 1529.069673 1440.830819 1662.616002 1426.572695 1364.137247 1352.156369 1614.049975 1922.110919 1552.153382 1473.897794 1.037432635 0.977564947 1.128040227 0.967891193 0.925530422 0.917401719 1.095089484 1.304100547 1.053094311 1 10.52542077 -4.343059357 3.24863106 1.007482364 1.321936627 0.700358333 0.059849301 0.11536334 1.945050437 0.008180167 0.079846278 4.54E-05 4.343059357 0.314454263 VLGAGGAGPAPAT(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 VLGAGGAGPAPATPSR 16 0 B7WPE2;Q32P44;H7C355;G3V195 B7WPE2 EML3 Echinoderm microtubule-associated protein-like 3 1 0 VLGAGGAGPAPAT(0.842)PS(0.158)R 137.73 0.0011932 11007000 510.59 755.32 479.98 695.55 590.86 974.82 718.69 507.2 470.96 525.96 TRUE FALSE FALSE 470.1762627 820.6064952 497.768481 692.6719984 583.8143804 772.6313435 738.8545071 661.8429451 419.2968663 544.2370709 0.863918112 1.50781073 0.914617007 1.272739465 1.072720716 1.419659529 1.357596802 1.216093097 0.770430551 1 9.088091419 -7.28712244 24.93302072 0.935739098 1.243117162 0.493851839 0.170148542 474.416907 460560.931 0.026652272 0.030483913 5.16E-08 7.28712244 0.307378064 VLGDHLLLDPTHELPPYTPPPMLS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 1 VLGDHLLLDPTHELPPYTPPPMLSPVR 27 0 Q05GC8;Q96PN7-2;Q96PN7-3;Q96PN7-4;Q96PN7-5;Q96PN7 Q05GC8 BCAR2;TRERF1 Transcriptional-regulating factor 1 1 0 VLGDHLLLDPTHELPPY(0.001)T(0.001)PPPMLS(0.999)PVR 79.237 2.26E-05 6704600 826.01 669.11 667.88 633.26 645.34 1267.5 867.94 479.64 683.91 676.79 TRUE FALSE FALSE 760.6304369 726.9448869 692.6322203 630.6397379 637.644742 1004.606212 892.2920605 625.880028 608.8867841 700.3084021 1.086136386 1.038035364 0.989038855 0.900517166 0.910519908 1.434519719 1.274141589 0.893720575 0.869455203 1 9.451846586 -5.286824133 24.98935421 1.019084238 1.208128829 0.3119652 0.144505504 696.4330225 685584.1644 0.019295168 0.043159824 5.17E-06 5.286824133 0.189044591 VLGRS(ph)PLTILQDDNS(ph)PGTLTLR ddPTM_HeLa_Curcumin_4h_R1 2 VLGRSPLTILQDDNSPGTLTLR 22 1 Q99618;J3KMY0 Q99618 CDCA3 Cell division cycle-associated protein 3 2 0 VLGRS(1)PLT(0.02)ILQDDNS(0.691)PGT(0.213)LT(0.076)LR;VLGRS(1)PLT(0.194)ILQDDNS(0.708)PGT(0.091)LT(0.007)LR ; 106.33 2.99E-05 29857000 1678.35 1299.7 1268.7 1490.47 1379.96 2852.1 2174.58 1244.19 1824.77 1329.23 TRUE FALSE FALSE 1545.506827 1412.040277 1315.719138 1484.30283 1363.504878 2260.54231 2235.592862 1623.537803 1624.597296 1375.420644 1.123661211 1.026624315 0.956594002 1.079162827 0.991336639 1.643527979 1.625388475 1.180393657 1.181163962 1 10.42565719 -5.268514444 24.99767792 1.047104539 1.497331885 0.688337377 0.133049899 196.672836 694887.1698 0.017430302 0.039765058 5.39E-06 5.268514444 0.450227347 VLGS(ph)EGEEEDEALS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 4 VLGSEGEEEDEALSPAK 17 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;M0QY71;M0R1G7;F5GZ28 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 2 0 VLGS(1)EGEEEDEALS(1)PAK;VLGS(1)EGEEEDEALS(1)PAK;VLGS(1)EGEEEDEALS(1)PAK;VLGS(1)EGEEEDEALS(1)PAK ;;; 149.18 0.00050151 77285300 17609.9 15582.9 17070.6 16478.2 18364.5 19766.9 14738.2 8352.35 16580.3 14785.4 TRUE FALSE FALSE 16216.05783 16929.81644 17703.25145 16410.01757 18145.51533 15667.02212 15151.71423 10898.94307 14761.48257 15299.19155 1.059929068 1.106582422 1.157136401 1.072606845 1.186044065 1.024042484 0.99036045 0.712386862 0.964853765 1 13.9011678 -4.214076586 2.194017995 1.057838524 0.59480067 0.732830639 0.064693266 0.323307683 1.576865144 0.009605725 0.303875831 6.11E-05 4.214076586 -0.463037854 VLGS(ph)EGEEEDEALSPAK ddPTM_HeLa_Curcumin_4h_R1 4 VLGSEGEEEDEALSPAK 17 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;M0QY71;M0R1G7;F5GZ28 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK;VLGS(1)EGEEEDEALSPAK ;;; 288.16 9.53E-80 407744200 19411.2 14671.4 16220.7 16754.1 16628.3 17571.2 14531.9 14718.2 17683.6 16708.1 TRUE FALSE FALSE 17874.78304 15939.53044 16821.85341 16684.77597 16430.01838 13926.73505 14939.626 19205.71143 15743.75332 17288.70523 1.033899462 0.921962069 0.972996716 0.965067988 0.950332495 0.805539505 0.864126365 1.110881999 0.910638079 1 14.07754221 -7.259675284 24.90409108 1.01600808 0.935799402 0 0.08190284 177.34965 2503684.685 0.012381428 0.014745613 5.50E-08 7.259675284 -0.080208678 VLGSEGEEEDEALS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 6 VLGSEGEEEDEALSPAK 17 0 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;M0QY71;M0R1G7;F5GZ28 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGSEGEEEDEALS(1)PAK;VLGS(0.001)EGEEEDEALS(0.999)PAK ;;;;; 264.03 4.88E-52 895551700 18164.3 14768.9 16396.4 16168.9 18138.9 20155.3 18218.7 15932.4 16508.3 14445.4 TRUE FALSE FALSE 16726.57649 16045.45791 17004.06501 16101.99738 17922.60546 15974.86358 18729.86769 20790.11542 14697.38079 14947.37657 1.119030915 1.073463148 1.137595278 1.077245716 1.199046895 1.068740291 1.253053845 1.390887244 0.983274939 1 13.86760468 -1 0.393970114 1.05350699 6.046929633 0.76396156 0.056722433 22.97755828 0.273785433 0.014462225 89.63452633 0.1 1 4.993422643 VLGSEGEEEDEALS(ph)PAKGQK ddPTM_HeLa_Curcumin_4h_R1 1 VLGSEGEEEDEALSPAKGQK 20 1 M0R0Q7;P18858-2;P18858;P18858-3;B4E135;M0QY71;M0R1G7;F5GZ28 M0R0Q7 LIG1 DNA ligase;DNA ligase 1 1 0 VLGSEGEEEDEALS(1)PAKGQK 91.583 0.00045724 4673900 1670.4 1627.2 1336.7 1604.6 1689.3 1833.6 1371.7 1298 2009.5 1422.7 TRUE FALSE FALSE 1538.186077 1767.847917 1386.239278 1597.96059 1669.156201 1453.290691 1410.18621 1693.754225 1789.062878 1472.138719 1.044864901 1.200870471 0.9416499 1.08546876 1.133830786 0.98719684 0.957916664 1.150539825 1.21528145 1 10.52369791 -8.472868819 1.207370884 1.007239855 1.058862248 0 0.103697751 0.855896991 2.524830447 0.023290425 0.014959766 3.37E-09 8.472868819 0.051622393 VLGTS(ph)PEAIDSAENR ddPTM_HeLa_Curcumin_4h_R1 4 VLGTSPEAIDSAENR 15 0 P27708;F8VPD4 P27708 CAD CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;Aspartate carbamoyltransferase;Dihydroorotase 1 0 VLGT(0.271)S(0.675)PEAIDS(0.054)AENR;VLGT(0.059)S(0.94)PEAIDSAENR;VLGT(0.135)S(0.865)PEAIDSAENR;VLGT(0.04)S(0.96)PEAIDSAENR ;;; 183.06 3.90E-05 23409300 8133.7 7549 7912.2 8831.1 8598.5 8942.5 7109.9 10694.5 8248.8 7705.8 TRUE FALSE FALSE 7489.909062 8201.501922 8205.433092 8794.559248 8495.968503 7087.724697 7309.384659 13955.20382 7343.927277 7973.575976 0.93934128 1.02858516 1.029078185 1.102962996 1.065515464 0.888901632 0.916700948 1.750181331 0.921033085 1 12.96101117 -4.258314559 24.99963177 0.985306989 1.750181612 0.921508439 0.06672775 58.00073125 464002.6172 0.009505883 0.090357545 5.52E-05 4.258314559 0.764874623 VLIGGDETPEGQR ddPTM_HeLa_Curcumin_4h_R1 1 VLIGGDETPEGQR 13 0 O60701;O60701-3;O60701-2 O60701 UGDH UDP-glucose 6-dehydrogenase 0 0 93.839 0.014458 2673100 1682.1 1506.8 1511.3 1338.8 1613.7 2421.7 1429 1419.1 1764.5 1587.2 FALSE FALSE TRUE 1548.96001 1637.041078 1567.310107 1333.2604 1594.457681 1919.412122 1469.093894 1851.777057 1570.938765 1642.355082 0.943133447 0.9967644 0.954306486 0.811797896 0.970836148 1.168694969 0.894504429 1.127513214 0.956515909 1 10.68155036 -5.4881528 24.92117573 0.959974257 1.050514466 0.278156037 0.08335111 707.0675502 507428.658 0.011332313 0.025328233 3.25E-06 5.4881528 0.09054021 VLIS(ph)T(ph)DLT(ph)S(ph)RGIDAEK ddPTM_HeLa_Curcumin_4h_R1 1 VLISTDLTSRGIDAEK 16 1 Q9UHI6 Q9UHI6 DDX20 Probable ATP-dependent RNA helicase DDX20 4 0 VLIS(1)T(1)DLT(1)S(1)RGIDAEK 54.501 0.0094128 0 547.79 498.73 564.6 567.88 413.18 466.42 457.1 699.09 508.77 529.13 TRUE FALSE FALSE 504.4318435 541.8379989 585.5245727 565.530263 408.2530984 369.6792344 469.9249958 912.2393228 452.9592039 547.5172281 0.92130771 0.989627305 1.069417623 1.032899485 0.745644296 0.675191967 0.858283487 1.666138116 0.827296714 1 9.096760551 -4.25767881 24.97107537 0.936825195 1.666138399 0.766183799 0.125298974 143.3150054 951604.7717 0.018192547 0.181897332 5.52E-05 4.25767881 0.729313204 VLISVGS(ph)YK ddPTM_HeLa_Curcumin_4h_R1 2 VLISVGSYK 9 0 Q8TEV9-2;Q8TEV9 Q8TEV9-2 SMCR8 Smith-Magenis syndrome chromosomal region candidate gene 8 protein 1 0 VLISVGS(1)YK;VLISVGS(1)YK ; 130.01 0.0039178 83230000 8408.2 6507.5 8747.4 7822.8 7381.3 7625.8 4272.2 4663.9 8105.5 7651.2 TRUE FALSE FALSE 7742.682098 7069.979303 9071.586339 7790.431326 7293.282818 6044.12312 4392.066434 6085.90164 7216.346929 7917.07863 0.977972111 0.893003548 1.145824964 0.984003278 0.92120884 0.763428457 0.554758471 0.768705469 0.911491128 1 12.95075246 -5.236269673 2.392451924 0.993035361 0.660166472 0.724151628 0.081135587 0.09545087 1.059991979 0.010273997 0.030389277 5.80E-06 5.236269673 -0.332868888 VLITTDLLAR ddPTM_HeLa_Curcumin_4h_R1 1 VLITTDLLAR 10 0 P60842;E7EQG2;Q14240;Q14240-2 P60842 EIF4A1;EIF4A2 "Eukaryotic initiation factor 4A-I;Eukaryotic initiation factor 4A-II;Eukaryotic initiation factor 4A-II, N-terminally processed" 0 0 127.46 0.0018131 1523800 1177.6 1146.7 1281.7 1330.2 1073.2 1022.9 988.08 1115.2 1102.1 1135.1 FALSE FALSE TRUE 1084.391717 1245.815638 1329.200929 1324.695985 1060.402791 810.7390095 1015.802866 1455.219346 981.2023873 1174.544641 0.923244362 1.060679684 1.131673402 1.12783792 0.902820339 0.690258149 0.86484824 1.238964698 0.835389608 1 10.19788583 -4.247673024 23.97892553 0.964433688 1.238965026 0.299264264 0.131313731 1389.80145 2420752.262 0.018394835 0.471033879 5.65E-05 4.247673024 0.274531338 VLKVPS(ph)Y(ph)LS(ph)Y(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 VLKVPSYLSYK 11 1 Q14332 Q14332 FZD2 Frizzled-2 4 0 VLKVPS(1)Y(1)LS(1)Y(1)K 44.765 0.017314 4966100 1758.9 1702 1156.7 1258.2 858.15 1326.5 1040.9 719.02 1548.2 1428.2 TRUE FALSE FALSE 1619.681209 1849.113296 1199.56832 1252.993902 847.9171217 1051.368947 1070.104853 938.245888 1378.366333 1477.829844 1.095986264 1.25123559 0.811709362 0.847860738 0.573758288 0.711427606 0.724105591 0.634880864 0.932696237 1 10.52926445 -6.370426616 2.103113287 1.060253443 0.680530214 0.729019858 0.105307924 0.111577668 0.965961225 0.015547346 0.025793237 4.26E-07 6.370426616 -0.379723229 VLLGETGK ddPTM_HeLa_Curcumin_4h_R1 1 VLLGETGK 8 0 P62280;M0QZC5;M0R1H6 P62280 RPS11 40S ribosomal protein S11 0 0 101.28 0.012243 4854700 5586.9 4020.4 5200.9 5451 5760.4 5497.7 4760.5 4179.5 4807.3 4204.9 FALSE FALSE TRUE 5144.69097 4367.905461 5393.649929 5428.445206 5691.710992 4357.415048 4894.066818 5453.81031 4279.951217 4351.019962 1.182410335 1.003880814 1.239628863 1.247625902 1.308132585 1.00146979 1.124809093 1.253455594 0.983666187 1 12.08713792 -9.619925857 0.467903206 0.933929168 1.176923235 0.356721826 0.096957096 2.353571093 0.555972708 0.281784404 0.026929116 2.40E-10 9.619925857 0.242994067 VLLGETGK(ac)EK ddPTM_HeLa_Curcumin_4h_R1 2 VLLGETGKEK 10 1 P62280;M0QZC5;M0R1H6 P62280 RPS11 40S ribosomal protein S11 0 1 ; VLLGETGK(1)EK;VLLGETGK(1)EK 140.45 2.83E-05 5657000 1938.14 2393.7 1760.1 1865.15 3267.4 4857.6 3483 3112.1 5181.4 2186.77 FALSE TRUE FALSE 1784.734174 2600.600762 1825.330854 1857.432503 3228.438389 3850.079004 3580.723606 4060.964964 4613.013383 2262.760095 0.788742111 1.149304678 0.806683333 0.820870276 1.426770075 1.701496775 1.58245835 1.794695325 2.03866658 1 11.14386792 -5.612661544 3.537747905 0.905913047 1.671858736 0.2538049 0.375860744 0.052540674 1.292064918 0.018177122 0.038558503 2.44E-06 5.612661544 0.765945689 VLLPEYGGTK ddPTM_HeLa_Curcumin_4h_R1 2 VLLPEYGGTK 10 0 P61604;B8ZZL8;B8ZZ54 P61604 HSPE1 "10 kDa heat shock protein, mitochondrial" 0 0 ; ; 138.08 9.96E-12 19879000 20108.7 15260.3 18584.8 20216.7 19960.3 28406 21491.8 20249.2 20221.2 15588.4 FALSE FALSE TRUE 18517.07518 16579.33233 19273.56904 20133.04865 19722.28646 22514.2754 22094.80207 26423.08786 18002.98495 16130.09574 1.147982968 1.027850832 1.194882495 1.248166717 1.222701141 1.395793042 1.36978741 1.638123436 1.116111475 1 13.97746738 -1 0.255147338 1.024774878 4.81108242 0.889581703 0.060207678 9.591060339 0.120279638 0.030038625 15.8837695 0.1 1 3.786307543 VLLQASQDENFGNT(ph)TPR ddPTM_HeLa_Curcumin_4h_R1 2 VLLQASQDENFGNTTPR 17 0 P57740;G3V1T4 P57740 NUP107 Nuclear pore complex protein Nup107 1 0 VLLQASQDENFGNT(0.9)T(0.1)PR;VLLQAS(0.187)QDENFGNT(0.697)T(0.116)PR ; 127.83 0.00098353 48037300 3877.3 3156.7 3703.7 3919.5 3812.4 6083.7 6402.9 5896.7 4600.1 3803 TRUE FALSE FALSE 3570.407614 3429.551082 3840.96238 3903.282148 3766.93962 4821.872043 6582.548141 7694.576685 4095.480539 3935.153967 0.90731078 0.871516365 0.976064066 0.991900744 0.957253427 1.225332499 1.672754916 1.955343234 1.040742134 1 11.94220437 -4.722253367 1.597471283 0.950141984 2.007132661 0.980767734 0.047836704 0.044214453 0.183122929 0.007003166 0.055380061 1.90E-05 4.722253367 1.056990677 VLLS(ph)DSNLHDA ddPTM_HeLa_Curcumin_4h_R1 2 VLLSDSNLHDA 11 0 H3BV90;Q6FI81-3;Q6FI81;Q6FI81-2 H3BV90 CIAPIN1 Anamorsin 1 0 VLLS(0.982)DS(0.018)NLHDA;VLLS(0.901)DS(0.099)NLHDA ; 120.55 0.0041275 42291000 9272.5 7600.4 7982.7 8212.4 8482.6 10298.6 5364.2 6245.3 9182.8 8054.5 TRUE FALSE FALSE 8538.571841 8257.344709 8278.545884 8178.419265 8381.450535 8162.554271 5514.705015 8149.46322 8175.469814 8334.393275 1.024498312 0.990755348 0.993299165 0.981285499 1.005646153 0.979381942 0.661680441 0.977811216 0.98093161 1 13.02486146 -4.941056672 13.2966101 1.005635791 0.819752986 0.483114981 0.072065183 0.543965832 121.6992287 0.008413684 0.025250664 1.15E-05 4.941056672 -0.185882804 VLLVPGPEKEN ddPTM_HeLa_Curcumin_4h_R1 1 VLLVPGPEKEN 11 1 Q99536-3;Q99536;K7EJM4;Q99536-2 Q99536-3 VAT1 Synaptic vesicle membrane protein VAT-1 homolog 0 0 99.802 0.0037551 0 3360.9 3103.5 2801.5 3294.2 2914.6 4611.5 3027.4 2825.6 3585.3 3200.8 FALSE FALSE TRUE 3094.881219 3371.752711 2905.326054 3280.569473 2879.845299 3655.022918 3112.340696 3687.112433 3192.00156 3312.027562 0.934437036 1.018032806 0.877204673 0.990501864 0.869511272 1.103560538 0.939708574 1.11324932 0.963760567 1 11.69349896 -1.000003646 1.040441801 0.964875358 183.493373 0.298306933 0.065802355 1725.842609 1.899532205 0.009056809 751870.6507 0.099999161 1.000003646 182.5284977 VLNNMEIGT(ph)SLFDEEGAK ddPTM_HeLa_Curcumin_4h_R1 1 VLNNMEIGTSLFDEEGAK 18 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 1 0 VLNNMEIGT(0.5)S(0.5)LFDEEGAK 69.148 0.0076222 0 785.26 743.68 583.48 791.5 561.73 1018.9 694.62 502.88 992.24 646.21 TRUE FALSE FALSE 723.1058424 807.9603854 605.1042821 788.2249827 555.0317366 807.5686546 714.1091677 656.205797 883.3937545 668.6657494 1.081416004 1.208317289 0.90494284 1.178802688 0.830058571 1.207731449 1.067961337 0.981365948 1.321129062 1 9.385141411 -9.391159607 1.221902093 1.00128748 1.060974723 0 0.155701988 1.390149217 3.830613394 0.066071151 0.018458852 4.06E-10 9.391159607 0.059687243 VLNNMEIGTSLFDEEGAK ddPTM_HeLa_Curcumin_4h_R1 4 VLNNMEIGTSLFDEEGAK 18 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 0 ;;; ;;; 210.14 6.87E-12 41146800 3973.07 3189.22 3502.21 3226.06 3126.5 5006.26 3598.31 3573.6 3762.79 3505.49 FALSE FALSE TRUE 3658.597317 3464.881966 3632.004983 3212.711419 3089.218529 3967.905244 3699.268894 4663.174189 3350.021351 3627.305517 1.008626734 0.955221982 1.001295581 0.885701908 0.851656558 1.093898825 1.019839348 1.285575248 0.923556435 1 11.82468255 -3.856283145 1.45632985 0.984948448 1.772515417 0.667537354 0.066669542 1.598677051 1.381430915 0.009494971 2.436888564 0.000139225 3.856283145 0.787566968 VLNT(ph)GSDVEEAVADALKKPAR ddPTM_HeLa_Curcumin_4h_R1 2 VLNTGSDVEEAVADALKKPAR 21 2 E3W994;J3KR49;O75122 E3W994 CLASP2 CLIP-associating protein 2 1 0 VLNT(0.589)GS(0.411)DVEEAVADALKKPAR;VLNT(0.676)GS(0.324)DVEEAVADALKKPAR ; 91.618 0.00018533 103787000 20090.3 15550.4 18173 18909.7 16546.5 18602.7 11657.7 8803.1 19866.3 17077.6 TRUE FALSE FALSE 18500.13156 16894.50728 18846.50737 18831.45667 16349.19379 14744.29032 11984.78369 11487.12467 17687.01659 17671.04533 1.046917781 0.956055908 1.0665191 1.065667385 0.925196755 0.834375672 0.678215887 0.650053489 1.00090381 1 14.10909976 -5.049966152 1.489341135 1.023300059 0.639227351 0.937782226 0.036290205 0.073676504 0.292566021 0.005482905 0.026683802 8.91E-06 5.049966152 -0.384072709 VLNTGS(ph)DVEEAVADALK ddPTM_HeLa_Curcumin_4h_R1 3 VLNTGSDVEEAVADALK 17 0 E3W994;J3KR49;O75122 E3W994 CLASP2 CLIP-associating protein 2 1 0 VLNT(0.001)GS(0.999)DVEEAVADALK;VLNT(0.003)GS(0.997)DVEEAVADALK;VLNT(0.086)GS(0.914)DVEEAVADALK ;; 208.37 6.34E-11 40015600 6076.26 4930.04 5742.74 6526.6 6572.8 5716.6 4302.26 2356.8 5020.62 4917.54 TRUE FALSE FALSE 5595.317609 5356.17069 5955.570996 6499.594659 6494.423653 4530.912721 4422.969837 3075.377471 4469.870547 5088.424149 1.099616983 1.052618754 1.170415599 1.277329576 1.276313346 0.890435347 0.869221926 0.604387013 0.878439064 1 12.31300322 -4.578180835 1.701465706 1.086567801 0.593555145 0.606586666 0.124497424 0.275208265 1.18565038 0.017423536 0.18047218 2.64E-05 4.578180835 -0.493012656 VLPEAGAGEDS(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 2 VLPEAGAGEDSPGR 14 0 Q8WTV1;Q8WTV1-3;R4GNH0 Q8WTV1 THAP3 THAP domain-containing protein 3 1 0 VLPEAGAGEDS(1)PGR;VLPEAGAGEDS(1)PGR ; 137.73 0.00083917 10892400 2960.5 2604.25 2437.15 2588.34 2633.55 3143.1 2048.4 1936.06 2853.3 2474.82 TRUE FALSE FALSE 2726.173301 2829.349766 2527.472923 2577.630135 2602.146636 2491.18563 2105.872591 2526.355781 2540.300129 2560.819811 1.064570529 1.104860933 0.986978042 1.006564431 1.016138123 0.972807856 0.822343135 0.986541798 0.991987065 1 11.32239003 -5.048188058 3.6403406 1.030591192 0.902353241 0.461614996 0.050815434 0.131194946 3.52769232 0.007007317 0.020749141 8.95E-06 5.048188058 -0.128237951 VLPITVPKS(ph)PAFALK ddPTM_HeLa_Curcumin_4h_R1 2 VLPITVPKSPAFALK 15 1 Q9ULW0;Q9ULW0-2 Q9ULW0 TPX2 Targeting protein for Xklp2 1 0 VLPIT(0.023)VPKS(0.977)PAFALK;VLPIT(0.004)VPKS(0.996)PAFALK ; 134.14 0.0053645 131528000 5607.5 4135.82 3816.87 4977.3 3512.87 9343.4 7427.8 2890.38 6832.4 4511.66 TRUE FALSE FALSE 5163.660458 4493.301852 3958.32656 4956.705251 3470.98132 7405.473518 7636.204077 3771.643556 6082.902814 4668.439849 1.106078396 0.962484684 0.847890663 1.061747695 0.743499206 1.586284446 1.635707929 0.807902357 1.302984083 1 12.18872478 -5.256111906 24.99910619 1.012084633 1.372539202 0.274887294 0.251274233 374.5883869 1757744.212 0.030973431 0.076461885 5.54E-06 5.256111906 0.360454569 VLPPPAGYVPIRT(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 2 VLPPPAGYVPIRTPAR 16 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 VLPPPAGYVPIRT(1)PAR;VLPPPAGYVPIRT(1)PAR ; 157.5 0.00023725 140170000 3864.5 3374.2 3543.6 3917.5 3812.4 5340.3 3512.9 2126.9 4440.6 4040.1 TRUE FALSE FALSE 3558.620747 3665.850813 3674.928933 3901.290423 3766.93962 4232.661582 3611.46252 2775.382019 3953.47729 4180.493174 0.851244243 0.876894342 0.879065885 0.933212963 0.901075415 1.012479008 0.863884324 0.663888662 0.945696387 1 12.02945743 -9.347366446 0.956079611 1.003578937 0.878448641 0.171448332 0.084275217 0.725390758 1.132476683 0.065071686 0.015207027 4.49E-10 9.347366446 -0.125130297 VLPPPAGYVPIRT(ph)PARK ddPTM_HeLa_Curcumin_4h_R1 1 VLPPPAGYVPIRTPARK 17 2 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 VLPPPAGYVPIRT(1)PARK 82.121 0.0036116 33375000 4330 3259 3317.6 4574.7 3716.3 5549.8 3663 1721 4254.2 4513.4 TRUE FALSE FALSE 3987.275931 3540.693438 3440.553174 4555.771104 3671.98555 4398.708921 3765.773922 2245.724977 3787.524903 4670.240314 0.853762475 0.758139453 0.736697245 0.975489653 0.786251949 0.941859225 0.806334079 0.480858548 0.810991437 1 12.18928107 -2.979279652 0.054356146 1.366421664 3.28E-14 0.152670885 0.130019562 214.3415145 1.313055762 9.452874549 27.92591701 0.001048867 2.979279652 -1.366421664 VLPSEQESTK(ac)KPYR ddPTM_HeLa_Curcumin_4h_R1 2 VLPSEQESTKKPYR 14 2 Q96T23-3;Q96T23-2;Q96T23 Q96T23-3 RSF1 Remodeling and spacing factor 1 0 1 ; VLPSEQESTK(0.686)K(0.314)PYR;VLPSEQESTK(0.995)K(0.005)PYR 151.3 0.00015332 32403000 5172.3 4517.4 4655.1 5031 5416.2 6675.5 5428 3301.9 4029 3914.5 FALSE TRUE FALSE 4762.906997 4907.863927 4827.622101 5010.183055 5351.615352 5290.926052 5580.295071 4308.63411 3587.02878 4050.528584 1.175872951 1.211660114 1.191849903 1.2369208 1.321214069 1.306231012 1.377670829 1.063721443 0.885570539 1 11.98389447 -8.37599954 0.400728986 0.972378206 1.278732342 0.63018189 0.088518033 0.652727933 0.227089995 0.084033056 0.033239391 4.21E-09 8.37599954 0.306354136 VLPSITTEILK ddPTM_HeLa_Curcumin_4h_R1 1 VLPSITTEILK 11 0 P35232;C9JZ20;E7ESE2;E9PCW0;C9JW96;P35232-2 P35232 PHB Prohibitin 0 0 99.815 0.0019907 0 149.61 0 168.9 154.4 0 118.61 0 0 0 0 FALSE FALSE TRUE 137.7682106 0 175.1595826 153.7611337 0 94.00894899 0 0 0 0 0 VLQATVVAVGSGSK ddPTM_HeLa_Curcumin_4h_R1 2 VLQATVVAVGSGSK 14 0 P61604;B8ZZL8;S4R3N1 P61604 HSPE1;HSPE1-MOB4 "10 kDa heat shock protein, mitochondrial" 0 0 ; ; 214.61 6.54E-27 16098600 6536.9 4719.8 5260.2 6013.1 6039.4 8761.1 6529.9 6289.2 6339.1 5301.7 FALSE FALSE TRUE 6019.497467 5127.758481 5455.147639 5988.219385 5967.384099 6943.949102 6713.11142 8206.748128 5643.71659 5485.93368 1.097260342 0.934710257 0.994388186 1.091558837 1.087760889 1.265773432 1.223695329 1.495961965 1.028761359 1 12.42152147 -3.649291463 0.613989881 1.032300707 2.197751978 0.867654238 0.05734926 1.771384393 0.269657016 0.011143654 1.731061039 0.000224238 3.649291463 1.165451272 VLQLYPNNK ddPTM_HeLa_Curcumin_4h_R1 2 VLQLYPNNK 9 0 Q02790;H0YFG2 Q02790 FKBP4 "Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed" 0 0 ; ; 152.47 4.07E-07 4599100 6014.1 3830.7 4886.8 4640.9 4932.9 6249.9 4930.3 4627.8 4753 4691 FALSE FALSE TRUE 5538.077639 4161.808639 5067.909107 4621.697185 4874.078389 4953.600289 5068.630949 6038.794916 4231.607791 4854.011901 1.140927907 0.85739564 1.044066065 0.952139649 1.004134001 1.020516717 1.044214776 1.244083253 0.871775323 1 12.24496193 -4.261969141 5.513855288 1.036105949 1.251546924 0.334490242 0.089226122 0.127137921 14.93691391 0.011540818 0.102884119 5.47E-05 4.261969141 0.215440974 VLQSFTVDSSK ddPTM_HeLa_Curcumin_4h_R1 2 VLQSFTVDSSK 11 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 202.31 2.48E-22 8437200 4494 3144.6 3461.8 3509.8 3821.6 5080.8 3564.8 3387.1 4093.4 3430.5 FALSE FALSE TRUE 4138.295158 3416.405212 3590.097353 3495.277378 3776.029916 4026.984808 3664.818694 4419.811198 3644.364261 3549.70962 1.165812306 0.962446391 1.011377757 0.98466572 1.063757411 1.134454713 1.032427744 1.245119086 1.02666546 1 11.7934853 -4.255595817 24.03433842 1.061811878 1.245119226 0.454103357 0.063549112 339.9572873 1398156.522 0.010683139 0.125648419 5.55E-05 4.255595817 0.183307349 VLS(ph)EDEEDVDFDIIHNANDTFTVK ddPTM_HeLa_Curcumin_4h_R1 1 VLSEDEEDVDFDIIHNANDTFTVK 24 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 1 0 VLS(1)EDEEDVDFDIIHNANDTFTVK 72.231 0.00039326 2179500 574.81 406.76 696.31 613.36 472.52 738.37 383.66 366.38 639.35 604.95 TRUE FALSE FALSE 529.313182 441.9185219 722.1158611 610.8220788 466.8855076 585.2237389 394.424467 478.0875754 569.2149046 625.9719675 0.84558608 0.705971745 1.153591373 0.975797816 0.745856894 0.934904068 0.63009925 0.763752373 0.909329705 1 9.289954241 -4.999019099 1.34984284 0.924381497 0.694605118 0.259200491 0.129364544 0.528531184 1.639918641 0.019791109 0.113776022 1.00E-05 4.999019099 -0.22977638 VLS(ph)PLIIK ddPTM_HeLa_Curcumin_4h_R1 1 VLSPLIIK 8 0 Q8NCN4 Q8NCN4 RNF169 E3 ubiquitin-protein ligase RNF169 1 0 VLS(1)PLIIK 99.815 0.015161 148030000 6251.5 5422.5 5639.4 5917.6 5477.7 6680.2 5386.4 3093.4 6799.9 5489.6 TRUE FALSE FALSE 5756.687178 5891.196738 5848.401125 5893.114539 5412.382005 5294.651219 5537.527887 4036.56342 6053.967983 5680.363191 1.013436463 1.037116209 1.029582252 1.037453828 0.95282323 0.932097304 0.974854547 0.710617136 1.065771286 1 12.47176746 -3.634880527 1.115339135 1.008603551 6.70E-15 0.850809558 0.037310658 1.382954559 0.514968094 0.004804993 2.305088822 0.000231803 3.634880527 -1.008603551 ALSGT(ph)SPDDVQPGPSVGPPSK ddPTM_HeLa_Curcumin_4h_R1 1 ALSGTSPDDVQPGPSVGPPSK 21 0 A0A075B797;M0R3B2;Q9Y314 A0A075B797 NOSIP Nitric oxide synthase-interacting protein 1 0 ALS(0.002)GT(0.499)S(0.499)PDDVQPGPSVGPPSK 150.98 1.68E-05 5186900 3632.7 2844 3078.8 3497.5 3733.9 4750.9 4324 5206.7 3439.2 2821.3 TRUE FALSE FALSE 3345.167962 3089.822687 3192.903036 3483.028272 3689.375681 3765.509786 4445.319803 6794.198861 3061.928364 2919.339965 1.145864477 1.058397694 1.093707165 1.193087586 1.263770484 1.289849703 1.522713989 2.327306495 1.048842684 1 11.51142651 -1 0.68812577 1.075457557 145.2325064 0.976727492 0.056983372 29.65891933 0.15385974 0.011639896 6574.636848 0.1 1 144.1570488 up VLS(ph)PLRSPPLIGSESAYESFLSADDKASGR ddPTM_HeLa_Curcumin_4h_R1 1 VLSPLRSPPLIGSESAYESFLSADDKASGR 30 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 VLS(0.988)PLRS(0.012)PPLIGSESAYESFLSADDKASGR 104.26 8.14E-11 53680000 1097.6 732.86 559.3 632.71 294.44 1048.7 520.48 617.8 1592.3 918.96 TRUE FALSE FALSE 1010.723802 796.2051528 580.02815 630.0920137 290.9289953 831.1877987 535.083268 806.164376 1417.628674 950.8937916 1.062919761 0.837322906 0.609982056 0.662631326 0.305953197 0.874112131 0.562716123 0.847796445 1.490838079 1 9.893140401 -6.993893034 3.003249077 1.029287947 0.636164472 0.540504697 0.208319723 0.121750285 2.252503979 0.023335292 0.030316175 1.01E-07 6.993893034 -0.393123476 VLS(ph)PPKLNEVSSDANR ddPTM_HeLa_Curcumin_4h_R1 1 VLSPPKLNEVSSDANR 16 1 B7Z7F3;Q9H6Z4-3;Q9H6Z4-2;Q9H6Z4;K7ESQ0 B7Z7F3 RANBP3 Ran-binding protein 3 1 0 VLS(0.992)PPKLNEVS(0.006)S(0.001)DANR 126.91 0.0048819 39751000 1073.5 712.52 748.21 867.6 910.12 727.89 674.82 477.82 773.92 801.58 TRUE FALSE FALSE 988.5313422 774.1070539 775.9393208 864.0101011 899.2674134 576.917409 693.753633 623.5051184 689.0229123 829.4348453 1.191813134 0.93329459 0.935503645 1.041685319 1.084192952 0.695554825 0.836417275 0.751722841 0.830713728 1 9.695984847 -5.267786054 24.98184849 1.064368263 0.768750206 0.442581486 0.109498942 227.5563963 895711.2843 0.014490517 0.03315013 5.40E-06 5.267786054 -0.295618058 EPAPAS(ph)PAPAGVEIR ddPTM_HeLa_Curcumin_4h_R1 2 EPAPASPAPAGVEIR 15 0 Q14195-2 Q14195-2 DPYSL3 Dihydropyrimidinase-related protein 3 1 0 EPAPAS(1)PAPAGVEIR;EPAPAS(1)PAPAGVEIR ; 193.31 1.93E-06 68179000 3908.7 2919 3481.9 3329.5 4085.2 4432.9 4533.7 5022.9 3603.2 2886.7 TRUE FALSE FALSE 3599.322271 3171.305353 3610.942277 3315.723411 4036.486658 3513.466571 4660.90342 6554.359087 3207.937975 2987.01261 1.204990651 1.061698013 1.208880828 1.110046673 1.351345704 1.176247653 1.560389603 2.19428571 1.073961979 1 11.54448761 -1 0.707076238 1.103996751 147.1640725 0.931665095 0.088124664 52.86984251 0.254924388 0.016407744 12239.36457 0.1 1 146.0600757 up VLSAPPHFHFGQT(ph)NRTPEFLR ddPTM_HeLa_Curcumin_4h_R1 2 VLSAPPHFHFGQTNRTPEFLR 21 1 P26641;P26641-2 P26641 EEF1G Elongation factor 1-gamma 1 0 VLSAPPHFHFGQT(0.5)NRT(0.5)PEFLR;VLSAPPHFHFGQT(0.5)NRT(0.5)PEFLR ; 72.207 0.00093046 156080000 2290.6 1452.23 1705.42 1459.18 1669.3 9090 4522.7 3499.7 2917.2 2195.74 TRUE FALSE FALSE 2109.296593 1577.75429 1768.624365 1453.1423 1649.394688 7204.631535 4649.59479 4566.742419 2597.190458 2272.041802 0.928370504 0.69442133 0.778429501 0.639575513 0.725952615 3.17099427 2.046438928 2.009972887 1.143108572 1 11.14977366 -5.277312787 24.97588518 0.89111982 2.37286573 0.824044524 0.330747708 219.2455373 344969.8749 0.044850894 0.100595391 5.28E-06 5.277312787 1.48174591 VLSEDEEDVDFDIIHNANDTFTVK ddPTM_HeLa_Curcumin_4h_R1 2 VLSEDEEDVDFDIIHNANDTFTVK 24 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 116.45 5.83E-07 15857400 3093.7 2676.79 3154.3 3472.8 2988.5 3369.3 2790 2758.78 3067.5 2676.74 FALSE FALSE TRUE 2848.830381 2908.1598 3271.201133 3458.430474 2952.864089 2670.4692 2868.279891 3599.919322 2731.002925 2769.756516 1.028549031 1.049969477 1.181042851 1.248640613 1.066109628 0.964153053 1.035571132 1.29972411 0.986008304 1 11.43554344 -6.953896636 5.831759069 1.014651066 1.122733895 0.274019389 0.093702336 0.222937973 17.95315182 0.015558059 0.02042769 1.11E-07 6.953896636 0.108082829 VLSEPIGPES(ph)PSSTECPR ddPTM_HeLa_Curcumin_4h_R1 2 VLSEPIGPESPSSTECPR 18 0 Q56NI9;Q56NI9-2 Q56NI9;Q56NI9-2 ESCO2 N-acetyltransferase ESCO2 1 0 VLSEPIGPES(0.912)PS(0.084)S(0.004)TECPR;VLSEPIGPES(0.995)PS(0.005)STECPR ; 270.95 4.96E-54 35263000 5562 4668.2 5381.4 5585.4 5517.2 6837.5 5318.8 4527.6 6106 5840.9 TRUE FALSE FALSE 5121.761831 5071.698407 5580.839418 5562.289095 5451.410993 5419.325425 5468.031213 5908.044397 5436.187076 6043.87084 0.847430722 0.839147384 0.923388266 0.920318988 0.901973443 0.896664666 0.904723373 0.977526581 0.899454542 1 12.56125711 -9.496814301 1.268836953 0.999481538 0.894808855 0 0.047862889 0.308642045 0.896179845 0.027535865 0.006830127 3.19E-10 9.496814301 -0.104672683 VLSIGDGIAR ddPTM_HeLa_Curcumin_4h_R1 2 VLSIGDGIAR 10 0 P25705;P25705-2;P25705-3;K7ERX7;K7EK77;K7EQH4;K7EJP1 P25705 ATP5A1 "ATP synthase subunit alpha, mitochondrial" 0 0 ; ; 128.36 0.0016786 8473600 5973.1 5175.8 5034.4 6256.3 6104.1 9577.2 6485.9 5390.6 6351.7 5071.3 FALSE FALSE TRUE 5500.322832 5623.173089 5220.979293 6230.413088 6031.312594 7590.780763 6667.876898 7034.169125 5654.934401 5247.527298 1.04817422 1.071585295 0.994940854 1.18730456 1.149362786 1.446544312 1.270670264 1.340473089 1.07763792 1 12.35742205 -5.74888273 1.383749036 1.025242914 1.344165662 0.798056219 0.064766666 0.112184087 0.429329097 0.009127408 0.02358687 1.78E-06 5.74888273 0.318922748 VLSPLRS(ph)PPLIGSESAYESFLSADDKASGR ddPTM_HeLa_Curcumin_4h_R1 2 VLSPLRSPPLIGSESAYESFLSADDKASGR 30 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 VLS(0.177)PLRS(0.43)PPLIGS(0.157)ES(0.201)AY(0.033)ES(0.001)FLSADDKASGR;VLS(0.051)PLRS(0.912)PPLIGS(0.017)ES(0.001)AY(0.019)ES(0.001)FLSADDKASGR ; 87.357 1.45E-06 477707000 1803.17 1143.97 1397.56 1159.21 885.38 1875.94 1704.47 1336.27 1535.1 1620.05 TRUE FALSE FALSE 1660.447192 1242.849669 1449.354803 1154.413496 874.8224218 1486.848898 1752.292841 1743.692572 1366.703371 1676.346617 0.990515431 0.741403751 0.864591361 0.688648448 0.521862491 0.886957914 1.045304607 1.040174242 0.815286861 1 10.71110477 -7.28323043 21.57883274 0.995521246 0.822084382 0.051372595 0.158234993 164.2383057 162638.0372 0.027135788 0.031058273 5.21E-08 7.28323043 -0.173436865 VLSQSTPGT(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 VLSQSTPGTPSK 12 0 Q6MZP7;Q6MZP7-3 Q6MZP7 LIN54 Protein lin-54 homolog 1 0 VLSQST(0.003)PGT(0.912)PS(0.085)K 173.25 0.00039753 18838000 3934.6 4043.9 4314.7 3754.9 4047.7 5284.6 4986.6 1830.2 4557.5 4298.8 TRUE FALSE FALSE 3623.172258 4393.436697 4474.606578 3739.363219 3999.433821 4188.51439 5126.510575 2388.219555 4057.553652 4448.18298 0.814528601 0.987692439 1.005940313 0.840649595 0.8991163 0.941623672 1.152495434 0.536897777 0.912182271 1 12.11900042 -4.238667954 24.40231276 0.93031817 0.536897183 0.635742102 0.092793744 2597.791224 2783787.74 0.013990435 0.991629894 5.77E-05 4.238667954 -0.393420986 VLSRNS(ph)ADDEELTNDSLTLSQSK ddPTM_HeLa_Curcumin_4h_R1 1 VLSRNSADDEELTNDSLTLSQSK 23 1 A0A0U1RRH6;O94880 A0A0U1RRH6 PHF14 PHD finger protein 14 1 0 VLS(0.277)RNS(0.722)ADDEELT(0.001)NDSLTLSQSK 85.013 0.00016463 20482000 2288.2 1927 1808.3 2055.7 2087.2 2478.3 1831.4 2109.8 2400.6 2094.7 TRUE FALSE FALSE 2107.086556 2093.561293 1875.317189 2047.194058 2062.311503 1964.272644 1882.784155 2753.068308 2137.260186 2167.490669 0.972131777 0.965891721 0.865201966 0.944499595 0.951474224 0.906242722 0.868646948 1.270163857 0.986052774 1 11.08181007 -4.250710309 24.80433853 0.960625896 1.270164053 0.802346104 0.048191456 544.7384907 1259344.077 0.007561162 0.147722 5.61E-05 4.250710309 0.309538157 VLSRNSADDEELT(ph)NDSLTLSQSK ddPTM_HeLa_Curcumin_4h_R1 1 VLSRNSADDEELTNDSLTLSQSK 23 1 A0A0U1RRH6;O94880 A0A0U1RRH6 PHF14 PHD finger protein 14 1 0 VLS(0.014)RNS(0.212)ADDEELT(0.762)NDS(0.01)LT(0.003)LSQSK 83.359 0.00035589 11826000 2534.2 2389.5 2455.9 2608.3 2490 2812.6 2358.3 3058.7 3124.4 2746.9 TRUE FALSE FALSE 2333.615396 2596.037733 2546.917814 2597.507546 2460.308376 2229.235055 2424.467551 3991.283549 2781.661137 2842.354571 0.82101488 0.913340566 0.896059148 0.913857677 0.86558813 0.784291685 0.852978575 1.404217331 0.978646776 1 11.47287082 -4.258403156 24.99167333 0.897162537 1.404217517 0.857468731 0.062645327 95.32003752 784555.8398 0.010721809 0.101353779 5.52E-05 4.258403156 0.507054981 GSTES(ph)CNTTTEDEDLKVR ddPTM_HeLa_Curcumin_4h_R1 1 GSTESCNTTTEDEDLKVR 18 1 Q5SWX3;Q13555-5;Q13555-11;Q8WU40;Q13555-10;Q13555-4 Q5SWX3 CAMK2G 1 0 GS(0.004)T(0.015)ES(0.977)CNT(0.003)TTEDEDLKVR 116.45 0.00019577 6541500 712.07 526.96 535.4 779.93 744.34 1393 1071.8 984.68 627.82 403.75 TRUE FALSE FALSE 655.7089081 572.5080743 555.242395 776.7028563 735.4642316 1104.076098 1101.871823 1284.904399 558.9497167 417.7802824 1.569506594 1.370356856 1.32902968 1.859118032 1.760409149 2.642719496 2.63744334 3.075550602 1.337903535 1 8.706600594 -1 0.249598216 1.086173568 14.61776669 0.913254237 0.193644495 9.556048418 0.119190876 0.115682939 54.90663133 0.1 1 13.53159312 up VLSSAAS(ph)LPGSELPSSRPEGSQGGELSR ddPTM_HeLa_Curcumin_4h_R1 1 VLSSAASLPGSELPSSRPEGSQGGELSR 28 1 O15027;O15027-5;A0A0C4DH09;Q8N9G1 O15027 SEC16A Protein transport protein Sec16A 1 0 VLS(0.005)S(0.015)AAS(0.706)LPGS(0.191)ELPS(0.026)S(0.026)RPEGS(0.031)QGGELS(0.002)R 49.944 0.0075746 49421000 685.69 443 560.13 620.63 648.44 747.23 720.19 236.45 526.16 559.32 TRUE FALSE FALSE 631.416913 481.290946 580.8889105 618.0619975 640.7077765 592.246075 740.3965931 308.5425165 468.4415644 578.7563284 1.090989216 0.831595133 1.003684767 1.06791402 1.107042368 1.023308163 1.27928898 0.53311299 0.809393421 1 9.176812253 -4.243827411 24.65097002 1.043497508 0.533112483 0.561967482 0.128871744 1342.379884 1878856.425 0.013991729 0.568251421 5.70E-05 4.243827411 -0.510385025 VLSSAASLPGSELPS(ph)SRPEGSQGGELSR ddPTM_HeLa_Curcumin_4h_R1 1 VLSSAASLPGSELPSSRPEGSQGGELSR 28 1 O15027;O15027-5;A0A0C4DH09;Q8N9G1 O15027 SEC16A Protein transport protein Sec16A 1 0 VLS(0.001)S(0.002)AAS(0.052)LPGS(0.016)ELPS(0.364)S(0.364)RPEGS(0.171)QGGELS(0.03)R 41.214 0.019433 25872000 557.21 383.82 484.21 595.11 594.28 704.67 469.13 288.96 543.47 559.52 TRUE FALSE FALSE 513.1062405 416.9956905 502.1552486 592.6475925 587.1935991 558.5134987 482.2925252 377.0625738 483.8527007 578.9632784 0.886250061 0.720245491 0.867335231 1.023635893 1.014215618 0.964678624 0.833027833 0.651272003 0.835722608 1 9.177328036 -13.52287874 0.018121896 2.088013966 5.35E-13 0 0.119496902 5009.157048 7.325108032 544.3141728 326.0231661 3.00E-14 13.52287874 -2.088013966 VLSSAASLPGSELPSSRPEGSQGGELS(ph)R ddPTM_HeLa_Curcumin_4h_R1 2 VLSSAASLPGSELPSSRPEGSQGGELSR 28 1 O15027;O15027-5;A0A0C4DH09;Q8N9G1 O15027 SEC16A Protein transport protein Sec16A 1 0 VLSSAASLPGSELPS(0.086)S(0.086)RPEGS(0.17)QGGELS(0.658)R;VLSSAAS(0.001)LPGS(0.004)ELPS(0.191)S(0.191)RPEGS(0.224)QGGELS(0.389)R ; 71.623 9.89E-05 29755000 1744.37 1191.91 1974.45 2225.1 1941.82 2287.6 1564.02 926.8 1823.03 2062.5 TRUE FALSE FALSE 1606.301274 1294.933389 2047.624854 2215.893126 1918.665065 1813.125973 1607.902192 1209.377054 1623.04817 2134.171721 0.752657932 0.606761572 0.959447093 1.03829186 0.899020939 0.849568924 0.753408067 0.566672795 0.760504955 1 11.05946055 -9.371105233 1.122904731 0.998858584 0.808701387 0 0.156118122 0.665720515 1.515831079 0.09725656 0.025766951 4.25E-10 9.371105233 -0.190157198 VLSSIEQK ddPTM_HeLa_Curcumin_4h_R1 2 VLSSIEQK 8 0 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 0 ; ; 124.98 0.0021859 52336000 12093 7925.4 10215.5 8933.1 10264.4 11369.7 9547.5 9553.2 11109.9 8963.7 FALSE FALSE TRUE 11135.82629 8610.436261 10594.09542 8896.137199 10142.00373 9011.496057 9815.377154 12465.9267 9891.171766 9275.187908 1.200603848 0.928330115 1.14219739 0.959132827 1.093455339 0.971570188 1.058240248 1.344007995 1.066412008 1 13.17916079 -4.259983116 24.24877202 1.069405554 1.344008125 0.518130448 0.083471497 62.12907357 1034365.532 0.013156301 0.11066407 5.50E-05 4.259983116 0.27460257 SNS(ph)FSDEREFSGPSTPT(ph)GTLEFEGGEVSLEGGK ddPTM_HeLa_Curcumin_4h_R1 1 SNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGK 33 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 2 0 S(0.396)NS(0.459)FS(0.105)DEREFS(0.038)GPS(0.051)T(0.193)PT(0.424)GT(0.319)LEFEGGEVS(0.016)LEGGK 43.752 0.0096847 6584600 2976.8 2335.8 2444.2 2773.5 2524.4 3777.2 3267.1 3315.9 2998.4 2053.6 TRUE FALSE FALSE 2741.183139 2537.696144 2534.784202 2762.023992 2494.298179 2993.766142 3358.766033 4326.902645 2669.483022 2124.962447 1.289991333 1.194231054 1.192860705 1.299798966 1.173808122 1.408856023 1.580623713 2.036225464 1.256249505 1 11.05322163 -1 0.51392533 1.138015854 32.60900896 0.901296656 0.08572397 25.69304172 0.237814821 0.021388496 883.8557723 0.1 1 31.47099311 up VLSSTS(ph)EEDEPGVVK ddPTM_HeLa_Curcumin_4h_R1 2 VLSSTSEEDEPGVVK 15 0 Q8NI08-2;Q8NI08;Q8NI08-7;Q8NI08-4;Q8NI08-3 Q8NI08-2 NCOA7 Nuclear receptor coactivator 7 1 0 VLS(0.065)S(0.067)T(0.158)S(0.709)EEDEPGVVK;VLSST(0.02)S(0.98)EEDEPGVVK ; 264.58 2.03E-50 23635800 7988.5 6937.1 7075.7 7505.5 7274.9 8512.3 7012.4 6753.1 8672 7652.3 TRUE FALSE FALSE 7356.201796 7536.712013 7337.931666 7474.44423 7188.151569 6746.753027 7209.149071 8812.089103 7720.703296 7918.216855 0.929022522 0.951819349 0.926715168 0.943955485 0.907799281 0.852054591 0.910451078 1.112888074 0.975055803 1 12.95095986 -9.265666716 0.779676426 1.004268072 0.935814273 0.064497974 0.063873595 1.316889438 1.294990887 0.057361315 0.012321764 5.42E-10 9.265666716 -0.068453799 VLSTS(ph)TDLEAAVADALKKPVR ddPTM_HeLa_Curcumin_4h_R1 1 VLSTSTDLEAAVADALKKPVR 21 2 Q7Z460 Q7Z460 CLASP1 CLIP-associating protein 1 1 0 VLS(0.041)T(0.16)S(0.638)T(0.16)DLEAAVADALKKPVR 131.35 1.86E-05 274280000 1019 906.04 1137.7 1175.1 1267.5 1255 884.85 769.45 1648.3 1302.8 TRUE FALSE FALSE 938.3450748 984.3540604 1179.864163 1170.237748 1252.38589 994.6988532 909.6765095 1004.051763 1467.485614 1348.072203 0.696064404 0.730193871 0.875223271 0.868082396 0.92901989 0.737867639 0.674798062 0.744805627 1.088580872 1 10.39668205 -9.444070505 1.157645478 1.00088001 0.777719964 0.586496795 0.085454297 0.352521525 0.839789748 0.063285434 0.015525991 3.60E-10 9.444070505 -0.223160047 VLSTS(ph)TDLEAAVADALLLGDSR ddPTM_HeLa_Curcumin_4h_R1 1 VLSTSTDLEAAVADALLLGDSR 22 0 Q7Z460-4;H0Y5T1;F8WA11;Q7Z460-2;Q7Z460-5;Q7Z460-3 Q7Z460-4 CLASP1 CLIP-associating protein 1 1 0 VLS(0.001)T(0.001)S(0.945)T(0.054)DLEAAVADALLLGDSR 224.12 1.11E-23 9459100 433.58 353.06 482.59 325.95 369.25 515.57 294.9 365.89 458.3 502.79 TRUE FALSE FALSE 399.2616855 383.5769332 500.4752099 324.6013053 364.8469349 408.6349703 303.1741003 477.4481766 408.0256366 520.2619151 0.767424395 0.737276595 0.9619678 0.623919022 0.701275501 0.785440868 0.582733603 0.917707337 0.784269663 1 9.023094291 -9.613062042 0.365050803 1.124892661 0.731954113 0.031013131 0.128947053 2.432168994 0.348059658 0.391009436 0.039705968 2.44E-10 9.613062042 -0.392938548 VLT(ph)PEEQLADK ddPTM_HeLa_Curcumin_4h_R1 3 VLTPEEQLADK 11 0 O75822-2;O75822;O75822-3 O75822-2 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 0 VLT(1)PEEQLADK;VLT(1)PEEQLADK;VLT(1)PEEQLADK ;; 149.82 0.0018785 27625000 8740 9489 10744 9146.9 12929.4 10861.9 11424.4 9565 7465.7 6710.9 TRUE FALSE FALSE 8048.219778 10309.18688 11142.18209 9109.052551 12775.22535 8609.019501 11744.93792 12481.32447 6646.731388 6944.103275 1.159000588 1.484595846 1.60455305 1.311768012 1.839722833 1.239759715 1.691354153 1.797399027 0.957176344 1 12.76157269 -7.301161391 1.020254207 1.040530412 1.592431425 0.640432194 0.183069433 0.207766196 0.426766845 0.037496504 0.04370128 5.00E-08 7.301161391 0.551901014 VLT(ph)PEEQLADKLR ddPTM_HeLa_Curcumin_4h_R1 2 VLTPEEQLADKLR 13 1 O75822-2;O75822;O75822-3 O75822-2 EIF3J Eukaryotic translation initiation factor 3 subunit J 1 0 VLT(1)PEEQLADKLR;VLT(1)PEEQLADKLR ; 95.9 0.0074872 116337000 11867.2 10666.2 10989 11818.7 12938.7 14729 13572.4 12543.7 10644.8 9029.3 TRUE FALSE FALSE 10927.8986 11588.1388 11396.26201 11769.79735 12784.41445 11674.03937 13953.20502 16368.21639 9477.092072 9343.067503 1.16962642 1.240292741 1.219755932 1.259735879 1.368331594 1.249486784 1.493428685 1.751910321 1.014344814 1 13.18968058 -1 0.222765424 1.019541118 4.533874407 0.883776073 0.07180695 11.85849406 0.142551388 0.054697582 15.18883082 0.1 1 3.51433329 VLT(ph)PELYAELR ddPTM_HeLa_Curcumin_4h_R1 2 VLTPELYAELR 11 0 P12277;G3V4N7;G3V461 P12277 CKB Creatine kinase B-type 1 0 VLT(1)PELYAELR;VLT(1)PELYAELR ; 130.69 0.0079498 14832500 2267.53 2144.8 2189.87 2077.39 2207.76 3166.57 3315.7 3039.1 2682.57 2233.97 TRUE FALSE FALSE 2088.052608 2330.186955 2271.028509 2068.794311 2181.433904 2509.787687 3408.729618 3965.7076 2388.298782 2311.600291 0.903293106 1.008040605 0.982448617 0.894961953 0.943689924 1.085736015 1.47461896 1.715568048 1.033179824 1 11.17467624 -4.675087872 1.989096487 0.953945712 1.727602529 0.970277555 0.044331157 0.043715675 0.302138025 0.006577114 0.045494609 2.11E-05 4.675087872 0.773656817 VLT(ph)PPQAAGDGILATTANQR ddPTM_HeLa_Curcumin_4h_R1 2 VLTPPQAAGDGILATTANQR 20 0 C9J9G2;Q96QT6-2;Q96QT6-5;Q96QT6-3;Q96QT6;K7EPF7;Q96QT6-4 C9J9G2 PHF12 PHD finger protein 12 1 0 VLT(1)PPQAAGDGILATTANQR;VLT(1)PPQAAGDGILATTANQR ; 248.94 2.85E-34 28883000 7067.4 5911.2 6014.1 6303.7 6145.8 8075.3 6151.5 3698.3 7484.5 6506.3 TRUE FALSE FALSE 6508.007833 6422.137788 6236.987837 6277.61696 6072.515349 6400.391753 6324.094534 4825.894645 6663.469075 6732.393441 0.966670752 0.953915995 0.926414639 0.932449509 0.901984621 0.950685935 0.939353083 0.716817086 0.989762279 1 12.71690377 -3.662083747 1.357274104 0.968189019 6.60E-19 0.829464078 0.031206809 1.866439495 0.944958886 0.005497653 3.714309627 0.000217729 3.662083747 -0.968189019 VLTANSNPSS(ph)PSAAK ddPTM_HeLa_Curcumin_4h_R1 4 VLTANSNPSSPSAAK 15 0 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 1 0 VLTANSNPS(0.01)S(0.982)PS(0.008)AAK;VLTANSNPS(0.066)S(0.929)PS(0.005)AAK;VLTANSNPS(0.07)S(0.929)PS(0.001)AAK;VLTANSNPS(0.079)S(0.914)PS(0.007)AAK ;;; 280.5 1.15E-63 347017000 21916.2 19511 20716.1 19990.4 21484 23455.8 19679.9 5384.12 19854.4 17272 TRUE FALSE FALSE 20181.50964 21197.4439 21483.85689 19907.68502 21227.81733 18590.80268 20232.06503 7025.713403 17676.42199 17872.20071 1.129212343 1.186056728 1.202082342 1.113891084 1.187756207 1.040207805 1.132041059 0.393108466 0.989045629 1 14.12542967 -4.259552938 24.99280725 1.094032039 0.393108228 0.89343553 0.074003774 42.60719037 564443.0481 0.011407345 0.098992215 5.50E-05 4.259552938 -0.700923811 VLTANSNPSSPSAAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 VLTANSNPSSPSAAKR 16 1 Q9NV56 Q9NV56 MRGBP MRG/MORF4L-binding protein 0 1 ; VLTANSNPSSPSAAK(1)R;VLTANSNPSSPSAAK(1)R 330.68 2.30E-178 5559200 444.35 545.63 390.92 429.83 376 707.7 275.45 337.94 430.56 399.44 FALSE TRUE FALSE 409.1792286 592.7918259 405.4078391 428.0514773 371.5164456 560.9150426 283.1783857 440.9763503 383.3286452 413.3205103 0.989980459 1.434218267 0.980855847 1.035640542 0.898857996 1.357094624 0.685130253 1.066911366 0.927436785 1 8.691117146 -3.117184201 12.43830721 1.024807976 0.95876268 0 0.20601139 0 0 0.024409035 0 0.000763512 3.117184201 -0.066045296 VLTEIIASR ddPTM_HeLa_Curcumin_4h_R1 2 VLTEIIASR 9 0 P08758;D6RBL5;E9PHT9 P08758 ANXA5 Annexin A5;Annexin 0 0 ; ; 135.71 0.00029262 15482700 3973.1 3031.2 4025.8 3561.3 3640.8 5072.1 3603.4 3981.3 4073.1 3613.2 FALSE FALSE TRUE 3658.624943 3293.203421 4174.999689 3546.564284 3597.385838 4020.089286 3704.501706 5195.180042 3626.29112 3738.758431 0.978566818 0.880828083 1.116680782 0.948594125 0.962187289 1.075247133 0.990837406 1.389546861 0.96991854 1 11.86834354 -4.261334344 24.43758028 0.992014407 1.389546968 0.788154966 0.061920101 1.862407614 432478.2736 0.007676297 0.059269902 5.48E-05 4.261334344 0.397532561 VLTLS(ph)DDLER ddPTM_HeLa_Curcumin_4h_R1 2 VLTLSDDLER 10 0 P55010 P55010 EIF5 Eukaryotic translation initiation factor 5 1 0 VLT(0.134)LS(0.866)DDLER;VLT(0.017)LS(0.983)DDLER ; 158.06 0.00062588 34412000 6449.1 5481.9 5345.6 5623.4 5424.1 6964.7 4347.2 2684.9 6592.1 5837.1 TRUE FALSE FALSE 5938.64693 5955.731009 5543.712638 5600.131861 5359.42115 5520.142712 4469.170732 3503.51365 5868.963123 6039.938791 0.983229654 0.986058173 0.91784252 0.927183545 0.887330375 0.913940174 0.739936428 0.580057807 0.971692483 1 12.56031821 -3.699921201 0.594142374 0.988333299 1.01E-21 0.943119372 0.029979377 0.914012405 0.137820713 0.005468013 0.720407545 0.000199562 3.699921201 -0.988333299 VLTLSDDLER ddPTM_HeLa_Curcumin_4h_R1 1 VLTLSDDLER 10 0 P55010 P55010 EIF5 Eukaryotic translation initiation factor 5 0 0 138.08 0.015138 5372600 1466 1334.1 1182.5 1243.6 1231.1 1921.5 1472.2 1410 1461.9 1252.5 FALSE FALSE TRUE 1349.964553 1449.413659 1226.32449 1238.454313 1216.419937 1522.95924 1513.50597 1839.902509 1301.533227 1296.024282 1.0416198 1.118353784 0.946220304 0.95557956 0.938578045 1.175100854 1.1678068 1.419651264 1.00425065 1 10.33987703 -4.307611476 1.208802276 1.014226542 1.570987621 0.8017679 0.063039185 0.458508196 0.583428452 0.009454447 0.311915637 4.92E-05 4.307611476 0.55676108 VLTPEEQLADKLR ddPTM_HeLa_Curcumin_4h_R1 1 VLTPEEQLADKLR 13 1 O75822-2;O75822;O75822-3 O75822-2 EIF3J Eukaryotic translation initiation factor 3 subunit J 0 0 120.6 0.00049687 1491700 754.04 579.74 584.15 548.1 565.31 729.93 468.62 479.19 740.82 474.12 FALSE FALSE TRUE 694.3569383 629.8501423 605.7991129 545.8321074 558.5690475 578.53429 481.768216 625.2928251 659.5538994 490.5956347 1.415334522 1.283847833 1.234823692 1.112590632 1.138552828 1.179248752 0.982006732 1.274558477 1.344394146 1 8.938390587 -6.259406425 24.10402659 1.211724632 1.131148919 0.139376576 0.124556553 305.4523587 3621611.26 0.025597448 0.041077804 5.50E-07 6.259406425 -0.080575714 VLTPELYAELR ddPTM_HeLa_Curcumin_4h_R1 1 VLTPELYAELR 11 0 P12277;G3V4N7;G3V461 P12277 CKB Creatine kinase B-type 0 0 92.838 0.017781 378990 0 64.485 0 0 0 0 0 0 0 0 FALSE FALSE TRUE 0 70.05879606 0 0 0 0 0 0 0 0 0 MGSKS(ph)PGNTSQPPAFFSK ddPTM_HeLa_Curcumin_4h_R1 1 MGSKSPGNTSQPPAFFSK 18 1 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;Q9Y618-2;H7C184 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 MGS(0.439)KS(0.499)PGNT(0.04)S(0.021)QPPAFFSK 67.413 0.0072572 116700000 6889.9 4762.6 5083.1 6173.1 4712.5 6701.6 4653.5 1832.7 7342.5 5714.4 TRUE FALSE FALSE 6344.557145 5174.257922 5271.484158 6147.557348 4656.306515 5311.612617 4784.064686 2391.481793 6537.04612 5912.974975 1.072989007 0.875068463 0.891511326 1.039672479 0.787472725 0.898297835 0.809079136 0.404446459 1.105542666 1 12.52966846 -3.987503458 0.652248415 1.014554311 2.95E-34 0.75420744 0.095046164 1.494866167 0.343960999 0.016005717 1.221216745 0.000102919 3.987503458 -1.014554311 down VLVDQTTGLSR ddPTM_HeLa_Curcumin_4h_R1 1 VLVDQTTGLSR 11 0 Q15717;Q15717-2 Q15717 ELAVL1 ELAV-like protein 1 0 0 97.597 0.012936 1806400 1232.6 988.41 1078.2 1005.3 735.39 1289 1112.5 969.34 1285.4 1250.7 FALSE FALSE TRUE 1135.038409 1073.843756 1118.15904 1001.140335 726.6209545 1021.64687 1143.713756 1264.887304 1144.394836 1294.161732 0.877045257 0.829760091 0.864002553 0.773582088 0.561460702 0.789427507 0.883748706 0.977379622 0.884274977 1 10.33780221 -8.047802069 0.663496419 0.987042007 0.798230628 0.176145609 0.105378323 0.56398349 0.556158913 0.044171402 0.028977618 8.96E-09 8.047802069 -0.188811379 DFLDGVYAFEYYPST(ph)PGR ddPTM_HeLa_Curcumin_4h_R1 1 DFLDGVYAFEYYPSTPGR 18 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 1 0 DFLDGVYAFEYYPS(0.024)T(0.976)PGR 221.78 6.34E-17 2290100 1272.6 903.36 1145.9 912.54 1164.1 1568.1 1484 1347.8 715.09 804.5 TRUE FALSE FALSE 1171.872367 981.4424131 1188.368062 908.7641513 1150.218868 1242.858384 1525.637046 1758.738015 636.6464161 832.4563151 1.407728365 1.178971671 1.427544053 1.091665875 1.38171679 1.493001328 1.832693222 2.11270908 0.764780571 1 9.701230756 -1 0.415575597 1.172834967 19.07784828 0.764707733 0.181680776 22.49845068 0.259153947 0.038255942 337.2283101 0.1 1 17.90501332 up VMDS(ph)DEDDDY ddPTM_HeLa_Curcumin_4h_R1 2 VMDSDEDDDY 10 0 O14737;K7EQA1 O14737 PDCD5 Programmed cell death protein 5 1 0 VMDS(1)DEDDDY;VMDS(0.996)DEDDDY(0.004) ; 114.97 0.0054676 115894000 4579.3 3890.8 4360.2 4120.6 4535.3 4728.3 4596 4139.5 4872.4 4476 TRUE FALSE FALSE 4216.843573 4227.103415 4521.792848 4103.550049 4481.21951 3747.597281 4724.95139 5401.614494 4337.90991 4631.540667 0.910462387 0.912677599 0.976304252 0.886001083 0.967544027 0.80914701 1.020168391 1.166267314 0.936601926 1 12.17727647 -4.384305359 3.746489268 0.941942491 1.166438229 0.645825161 0.053739743 0.124408503 2.763902057 0.007900937 0.059250596 4.13E-05 4.384305359 0.224495738 VMEK(ac)PSPLLVGR ddPTM_HeLa_Curcumin_4h_R1 1 VMEKPSPLLVGR 12 1 Q9UN86-2;Q9UN86;D6R9X5;D6RB17;E5RJU8;E5RIZ6;D6RAC7;D6RGJ4;E5RH42;D6RBW8;E5RH00;E5RIF8;E5RI46;D6RBR0;D6REX8;D6RBM9;D6R9A4;Q13283-2;D6RE13;Q13283 Q9UN86-2;Q13283 G3BP2;G3BP1 Ras GTPase-activating protein-binding protein 2;Ras GTPase-activating protein-binding protein 1 0 1 VMEK(1)PSPLLVGR 100.55 0.0087451 1703800 624.38 383.27 267.43 348.71 650.72 704.8 554.25 583.5 561.2 317.33 FALSE TRUE FALSE 574.9596642 416.398151 277.3411911 347.2671304 642.960589 558.6165353 569.8007633 761.4064639 499.6377641 328.3571939 1.751018936 1.268125562 0.844632602 1.05758953 1.958113302 1.701246526 1.735307689 2.318835945 1.521628804 1 8.359122253 -1 0.441351474 1.29474053 22.89843026 0.507029129 0.311337127 56.59488621 0.621597577 0.082965076 1105.453239 0.1 1 21.60368973 VMLGETNPADSKPGTIR ddPTM_HeLa_Curcumin_4h_R1 4 VMLGETNPADSKPGTIR 17 1 Q32Q12;P22392-2;J3KPD9;P22392;E7ERL0;O60361;P15531;P15531-2 Q32Q12;P15531 NME1-NME2;NME2;NME1;NME2P1 Nucleoside diphosphate kinase;Nucleoside diphosphate kinase B;Putative nucleoside diphosphate kinase;Nucleoside diphosphate kinase A 0 0 ;;; ;;; 130.21 0.00016634 93037000 9279.29 7908.95 8757.06 9049.4 8497.13 11896.2 10173.16 9117.46 10140.14 9427.99 FALSE FALSE TRUE 8544.824405 8592.564396 9081.604347 9011.955981 8395.807274 9428.794022 10458.59149 11897.33158 9027.792011 9755.611951 0.875888099 0.880781692 0.930910782 0.923771469 0.860613083 0.966499495 1.07205899 1.21953719 0.925394743 1 13.25201666 -4.490047845 1.931348769 0.928278504 1.243100961 0.8576476 0.039179951 0.189474486 1.02795814 0.007827273 0.089747645 3.24E-05 4.490047845 0.314822457 VMNTGSQFVMEGVK ddPTM_HeLa_Curcumin_4h_R1 1 VMNTGSQFVMEGVK 14 0 Q8WVM8-2;Q8WVM8-3;Q8WVM8 Q8WVM8-2 SCFD1 Sec1 family domain-containing protein 1 0 0 80.312 0.015019 30462000 1067.7 971.08 1117.6 1152.4 879.98 841.23 868.36 1096.7 1272.1 1189.8 FALSE FALSE TRUE 983.1904184 1055.015828 1159.019239 1147.631674 869.4868132 666.7494154 892.7238445 1431.078781 1132.553813 1231.145461 0.798598094 0.856938405 0.941415353 0.932165784 0.706242146 0.541568349 0.725116465 1.16239618 0.919918765 1 10.26578551 -5.768267977 24.97588672 0.903430798 0.762332442 0.128438124 0.15438147 232.4202584 850090.1316 0.023813467 0.043863912 1.71E-06 5.768267977 -0.141098356 VMPT(ph)KSPPPPGGGNLGMNSR ddPTM_HeLa_Curcumin_4h_R1 1 VMPTKSPPPPGGGNLGMNSR 20 1 Q02078-3;Q02078-5;Q02078;Q02078-8;Q02078-7;Q02078-4;Q02078-6;Q02078-2 Q02078-3;Q02078-8 MEF2A Myocyte-specific enhancer factor 2A 1 0 VMPT(0.964)KS(0.036)PPPPGGGNLGMNSR 70.335 0.0052136 28059000 1258 1312 1379.4 1509.7 1151.9 1595.4 1156.8 604.25 1543.9 1050.5 TRUE FALSE FALSE 1158.427973 1425.403434 1430.521777 1503.453261 1138.164345 1264.496056 1189.256695 788.4830434 1374.538033 1087.004797 1.065706403 1.31131292 1.316021587 1.383115572 1.047064694 1.163284707 1.094067568 0.725372184 1.264518829 1 10.08614259 -3.309558519 12.60141482 1.087791016 1.096596989 0 0.191687317 0 0 0.02529931 0 0.000490277 3.309558519 0.008805973 VMQEQGTHPK ddPTM_HeLa_Curcumin_4h_R1 1 VMQEQGTHPK 10 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 96.143 0.0042053 4829600 4313.9 4370.6 4642.5 4282.7 4043.4 5016 3438.9 3620.2 4364.9 4705.6 FALSE FALSE TRUE 3972.450263 4748.375189 4814.555134 4264.979322 3995.185096 3975.625058 3535.386279 4723.982315 3886.08139 4869.11925 0.815845753 0.975202074 0.988793843 0.875924187 0.820514941 0.81649778 0.726083322 0.970192364 0.798107664 1 12.24944512 -5.96041396 4.561978313 0.922111785 0.825523824 0.169393384 0.084280276 0.251551703 11.94383204 0.01324464 0.024169025 1.10E-06 5.96041396 -0.096587961 VMS(ph)PENFPTASVEGK ddPTM_HeLa_Curcumin_4h_R1 2 VMSPENFPTASVEGK 15 0 H3BRU9;H3BSP3;H3BTW3;Q3L8U1-2;Q3L8U1-3;Q3L8U1 H3BRU9 CHD9 Chromodomain-helicase-DNA-binding protein 9 1 0 VMS(1)PENFPTASVEGK;VMS(1)PENFPTASVEGK ; 103.43 0.0034089 17088900 6166.7 5390.2 5988.3 5415 5576.6 6553.4 4980.6 2357.28 5762.2 4865.3 TRUE FALSE FALSE 5678.599188 5856.10487 6210.231666 5392.594165 5510.102687 5194.150968 5120.342231 3076.00382 5130.101076 5034.368813 1.127966464 1.16322524 1.233567086 1.071155961 1.094497223 1.03173827 1.017077298 0.611000889 1.019015743 1 12.2975952 -4.0377158 1.774530333 1.084284531 0.199730912 0.820743445 0.067065237 0.654017594 1.251256573 0.011318731 1.167918864 9.17E-05 4.0377158 -0.884553618 SQQTSFQSSPCNKS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 SQQTSFQSSPCNKSPK 16 1 Q12986-3;Q12986-2;Q12986 Q12986-3 NFX1 Transcriptional repressor NF-X1 1 0 SQQT(0.001)S(0.002)FQS(0.035)S(0.006)PCNKS(0.956)PK;SQQT(0.001)S(0.002)FQS(0.286)S(0.005)PCNKS(0.705)PK ; 87.208 0.0033579 81863000 6877.4 5137.7 5848.4 6035.4 5263.6 6612.2 4205.1 2282.53 6669.5 5821.6 TRUE FALSE FALSE 6333.046533 5581.779895 6065.146849 6010.427114 5200.835008 5240.755185 4323.083789 2978.46289 5937.872536 6023.900167 1.051319968 0.926605644 1.006847172 0.9977634 0.863366733 0.869993698 0.717655285 0.494440945 0.985718948 1 12.55648215 -3.98671571 0.639724022 1.018838682 1.10E-17 0.938776465 0.039985876 0.655988663 0.145241481 0.007011784 0.528243977 0.000103106 3.98671571 -1.018838682 down VMTIPY(ph)QPMPASSPVICAGGQDR ddPTM_HeLa_Curcumin_4h_R1 1 VMTIPYQPMPASSPVICAGGQDR 23 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 0 VMT(0.002)IPY(0.696)QPMPAS(0.151)S(0.151)PVICAGGQDR 63.125 0.0015175 30219000 981.93 1074.7 1261.9 1044.6 1050.7 1439.9 1024.5 951.53 1482.6 994.56 TRUE FALSE FALSE 904.2092044 1167.592279 1308.667124 1040.277722 1038.171089 1141.248509 1053.244713 1241.647117 1319.962489 1029.120886 0.878622926 1.134553088 1.271635958 1.010841133 1.00879411 1.108954764 1.023441198 1.206512406 1.2826117 1 10.00719674 -7.253988862 24.88918997 0.942683048 1.104533278 0 0.1366398 391.0985709 1306503.467 0.015135523 0.018343451 5.57E-08 7.253988862 0.16185023 VMTIPYQPMPAS(ph)SPVICAGGQDR ddPTM_HeLa_Curcumin_4h_R1 1 VMTIPYQPMPASSPVICAGGQDR 23 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 0 VMTIPYQPMPAS(0.5)S(0.5)PVICAGGQDR 96.351 6.62E-05 19777000 2989.2 2318 2377.5 2437.1 2311.2 3022.9 2514.2 2226.6 2883.6 2299.3 TRUE FALSE FALSE 2752.601666 2518.357591 2465.612241 2427.015926 2283.640449 2395.916465 2584.741685 2905.48009 2567.276294 2379.200504 1.156943966 1.058489012 1.036319653 1.020097265 0.959835224 1.007025873 1.086390862 1.221200183 1.079049996 1 11.21626114 -9.784519613 1.778712739 0.999891424 1.07833775 0 0.075531687 0.661577867 3.790575439 0.059088194 0.012483515 1.64E-10 9.784519613 0.078446326 VMTIPYQPMPASS(ph)PVICAGGQDR ddPTM_HeLa_Curcumin_4h_R1 2 VMTIPYQPMPASSPVICAGGQDR 23 0 Q15365 Q15365 PCBP1 Poly(rC)-binding protein 1 1 0 VMTIPY(0.041)QPMPAS(0.169)S(0.79)PVICAGGQDR;VMTIPY(0.001)QPMPAS(0.143)S(0.856)PVICAGGQDR ; 106.44 1.03E-05 70905000 3667.4 3526.8 3228.8 2937.3 3097.4 4918.5 2944.7 3068.8 4142.8 3061.8 TRUE FALSE FALSE 3377.12142 3831.640877 3348.462168 2925.146231 3060.465528 3898.347657 3027.320357 4004.462993 3688.345205 3168.197322 1.065944156 1.209407271 1.056898238 0.923284106 0.96599587 1.230462393 0.955534031 1.263956309 1.164177868 1 11.62944648 -1.000000074 0.010967994 8.71E-08 2.294886882 0 0.121668478 18843.41788 16.12405397 1435.205404 1980.073472 0.099999983 1.000000074 2.294886795 VMTSGTGAPAK(ac)IITAVPK ddPTM_HeLa_Curcumin_4h_R1 1 VMTSGTGAPAKIITAVPK 18 1 P51610-2;P51610;A6NEM2;P51610-4 P51610-2 HCFC1 Host cell factor 1;HCF N-terminal chain 1;HCF N-terminal chain 2;HCF N-terminal chain 3;HCF N-terminal chain 4;HCF N-terminal chain 5;HCF N-terminal chain 6;HCF C-terminal chain 1;HCF C-terminal chain 2;HCF C-terminal chain 3;HCF C-terminal chain 4;HCF C-terminal chain 5;HCF C-terminal chain 6 0 1 VMTSGTGAPAK(1)IITAVPK 134.81 0.00059363 1318800 133.06 0 0 206.24 152.93 206.81 214.62 168.48 58.206 70.076 FALSE TRUE FALSE 122.5281606 0 0 205.3866335 151.1064096 163.9152748 220.6416596 219.8487764 51.82094742 72.51113578 1.689784049 0 0 2.832484022 2.083906258 2.260553127 3.04286586 3.03193122 0.714661919 1 6.180130667 -6.236670139 24.75232343 1.123093438 2.619030529 0.694331215 0.619381566 414.4217488 414138.7419 0.10417078 0.172695008 5.80E-07 6.236670139 1.495937091 VNAS(ph)ASSLK ddPTM_HeLa_Curcumin_4h_R1 1 VNASASSLK 9 0 Q16658 Q16658 FSCN1 Fascin 1 0 VNAS(0.975)AS(0.008)S(0.017)LK 108.98 0.0094781 7398700 2504.1 1890.9 1854.1 2242 2251.3 3418.3 2308.9 1681.8 2865 2311.9 TRUE FALSE FALSE 2305.897843 2054.34097 1922.814577 2232.723198 2224.454718 2709.306048 2373.68152 2194.573078 2550.716668 2392.238353 0.963908065 0.858752627 0.803772155 0.933319707 0.929863329 1.132540177 0.9922429 0.917372249 1.066246875 1 11.22414543 -4.236394622 20.92388029 0.966001093 0.917371717 0.024208417 0.089346459 2681.234012 2239723.649 0.01223457 0.744730437 5.80E-05 4.236394622 -0.048629376 VNASASS(ph)LK ddPTM_HeLa_Curcumin_4h_R1 2 VNASASSLK 9 0 Q16658 Q16658 FSCN1 Fascin 1 0 VNASAS(0.019)S(0.981)LK;VNASAS(0.061)S(0.939)LK ; 155.26 0.0012407 48656000 13433.8 13623.9 12798.7 12434.4 12810.9 16329.3 13538 14120.7 11759.6 11116.1 TRUE FALSE FALSE 12370.50055 14801.48921 13273.03108 12382.94975 12658.13838 12942.41911 13917.83984 18426.03643 10469.6013 11502.38365 1.075472783 1.286819294 1.153937435 1.076555097 1.100479585 1.125194526 1.209996143 1.601931999 0.91021145 1 13.48964524 -1.129129711 0.895183102 1.068186323 199.9999999 0.73267912 0.092550954 244.6021647 0.679168124 0.014218999 99187.15695 0.074279725 1.129129711 198.9318136 VNASASSLK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 VNASASSLKK 10 1 Q16658 Q16658 FSCN1 Fascin 0 1 VNASASSLK(1)K 78.653 0.015038 3071400 2110.2 1766.3 2003.4 1775.9 2538.2 2704.8 2057 1878.4 2295.4 2126.4 FALSE TRUE FALSE 1943.175443 1918.971102 2077.647766 1768.551796 2507.933623 2143.793991 2114.713884 2451.115513 2043.600363 2200.292242 0.883144251 0.872143739 0.944259916 0.803780408 1.139818418 0.974322388 0.961105913 1.113995435 0.928785879 1 11.10347944 -5.754567173 24.99993445 0.928615674 1.035939595 0.459507138 0.072430247 156.2604529 568444.2007 0.011365322 0.022338575 1.76E-06 5.754567173 0.107323921 VNDAEPGS(ph)PEAPQGK ddPTM_HeLa_Curcumin_4h_R1 5 VNDAEPGSPEAPQGK 15 0 Q8N8A6 Q8N8A6 DDX51 ATP-dependent RNA helicase DDX51 1 0 VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK;VNDAEPGS(1)PEAPQGK ;;;; 269.87 9.02E-51 758557700 45264.5 39275.8 42090.1 42091.7 42750.7 44754.5 35861.8 26399.8 43115.4 36473.6 TRUE FALSE FALSE 41681.76706 42670.62514 43649.99613 41917.5357 42240.92582 35471.91221 36867.98559 34448.97749 38385.74849 37741.05489 1.104414468 1.130615593 1.156565344 1.110661475 1.119230132 0.939876014 0.976866855 0.912771983 1.017082024 1 15.20384713 -5.250324498 24.73793679 1.073625394 0.946541126 0.634488939 0.050248017 447.1325688 995161.5015 0.008983585 0.022662604 5.62E-06 5.250324498 -0.127084267 VNFPENGFLS(ph)PDKLSLLEK ddPTM_HeLa_Curcumin_4h_R1 2 VNFPENGFLSPDKLSLLEK 19 1 P31689 P31689 DNAJA1 DnaJ homolog subfamily A member 1 1 0 VNFPENGFLS(0.967)PDKLS(0.033)LLEK;VNFPENGFLS(0.999)PDKLS(0.001)LLEK ; 80.835 0.0018777 445300000 5853.6 5761.3 5322.1 5239.7 5468.5 7088.5 5818.8 5462.9 6484.7 5530.2 TRUE FALSE FALSE 5390.281383 6259.2811 5519.341708 5218.01951 5403.291709 5618.265196 5982.059868 7128.513062 5773.344634 5722.374038 0.94196593 1.093825929 0.964519563 0.911862712 0.944239519 0.981806704 1.045380786 1.245726514 1.008907246 1 12.48239809 -4.254631357 2.114218065 0.97411561 1.323903074 0.739930047 0.047085476 0.263288845 1.26779794 0.006754862 0.175666523 5.56E-05 4.254631357 0.349787464 VNGDAS(ph)PAAAESGAK ddPTM_HeLa_Curcumin_4h_R1 3 VNGDASPAAAESGAK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 1 0 VNGDAS(0.889)PAAAES(0.111)GAK;VNGDAS(1)PAAAESGAK;VNGDAS(0.968)PAAAES(0.032)GAK ;; 212.35 1.30E-10 690266000 13544.6 11404.9 13126.5 12508.6 14675.7 16029.6 12430.9 9060.3 11449.2 11312.3 TRUE FALSE FALSE 12472.53062 12390.68874 13612.97964 12456.84273 14500.70186 12704.88027 12779.6776 11822.74376 10193.2514 11705.40158 1.065536328 1.058544523 1.162965622 1.064196101 1.238804304 1.085386108 1.091776092 1.010024618 0.870816036 1 13.51488681 -7.986501563 0.71708731 1.009036486 1.108578881 0.367767143 0.073709382 0.518000686 0.590528305 0.020954944 0.014925638 1.03E-08 7.986501563 0.099542395 VNGDASPAAAESGAK ddPTM_HeLa_Curcumin_4h_R1 1 VNGDASPAAAESGAK 15 0 P29966 P29966 MARCKS Myristoylated alanine-rich C-kinase substrate 0 0 216.88 1.58E-26 1766300 564.69 525.07 587.77 675.21 955.92 672.21 528.94 465.31 612.89 605.66 FALSE FALSE TRUE 519.9941906 570.4547111 609.5532733 672.4161599 944.5212783 532.7860686 543.7806328 607.180877 545.6575004 626.7066399 0.829725038 0.910242009 0.972629352 1.072936071 1.507118671 0.850136307 0.867679706 0.968843855 0.870674516 1 9.291646468 -6.476262407 3.816968018 0.917162573 1.055799497 0.139519077 0.174949776 0.412905974 12.42338022 0.029074791 0.044243569 3.34E-07 6.476262407 0.138636924 VNGDDHHEEDMDMS(ph)D ddPTM_HeLa_Curcumin_4h_R1 2 VNGDDHHEEDMDMSD 15 0 Q5T757;Q05519-2;Q05519 Q5T757 SRSF11 Serine/arginine-rich splicing factor 11 1 0 VNGDDHHEEDMDMS(1)D;VNGDDHHEEDMDMS(1)D ; 118.52 0.0016733 163475000 6197 5254.2 6089.2 5802.9 5639.8 6958.7 5332.2 5101.7 6629.8 5604.7 TRUE FALSE FALSE 5706.500911 5708.349636 6314.871109 5778.889137 5572.549068 5515.387179 5481.807181 6657.184845 5902.527527 5799.462908 0.983970585 0.98428936 1.088871713 0.99645247 0.960873301 0.95101689 0.945226699 1.147896788 1.017771408 1 12.50170358 -9.485555816 0.00210533 1.68E-05 1.986536133 0 0.061040603 561922.8655 268.9795279 128208.3684 125599.1749 3.27E-10 9.485555816 1.986519323 VNGTTVS(ph)SPSTSLQR ddPTM_HeLa_Curcumin_4h_R1 1 VNGTTVSSPSTSLQR 15 0 A0A075B6G3;H0Y304;A0A087WTU7;A0A5H1ZRP8;A0A5H1ZRP7;A0A087WV90;A0A5H1ZRQ1;A0A5H1ZRP9;A0A5H1ZRQ8;P11532;P11532-11;P11532-4;P11532-2;P11532-3;P11532-14;P11532-8;P11532-12;P11532-17;P11532-6;P11532-5;P11532-7;P11532-15;P11532-9;P11532-16;P11532-13;A0A5H1ZRR9 A0A075B6G3 DMD Dystrophin 1 0 VNGTTVS(0.5)S(0.5)PSTSLQR 135.86 0.00061334 12478000 3406.4 2974.3 3374.4 3389.9 2994.4 3855.8 2551.1 1517.2 3588.6 3050.6 TRUE FALSE FALSE 3136.779846 3231.385239 3499.458232 3375.873492 2958.693736 3056.063616 2622.677 1979.787296 3194.939558 3156.608123 0.993718486 1.023689072 1.108613453 1.069462334 0.937301566 0.968147929 0.830852896 0.627188177 1.012143235 1 11.62415945 -4.246871685 1.216724902 1.010698087 0.435841812 0.8948081 0.042476603 0.382431967 0.454564993 0.006885284 0.278573561 5.66E-05 4.246871685 -0.574856275 VNGTTVSS(ph)PSTSLQR ddPTM_HeLa_Curcumin_4h_R1 3 VNGTTVSSPSTSLQR 15 0 A0A075B6G3;H0Y304;A0A087WTU7;A0A5H1ZRP8;A0A5H1ZRP7;A0A087WV90;A0A5H1ZRQ1;A0A5H1ZRP9;A0A5H1ZRQ8;P11532;P11532-11;P11532-4;P11532-2;P11532-3;P11532-14;P11532-8;P11532-12;P11532-17;P11532-6;P11532-5;P11532-7;P11532-15;P11532-9;P11532-16;P11532-13;A0A5H1ZRR9 A0A075B6G3 DMD Dystrophin 1 0 VNGTTVS(0.076)S(0.874)PS(0.04)T(0.005)S(0.005)LQR;VNGTTVS(0.219)S(0.735)PS(0.039)T(0.005)S(0.002)LQR;VNGTTVS(0.226)S(0.774)PSTSLQR ;; 226.06 1.08E-20 101229000 10686.2 8440.2 8728.8 9409.9 9390.9 11171.9 7983.5 4269.8 10992.3 9134.6 TRUE FALSE FALSE 9840.375994 9169.733279 9052.297007 9370.964327 9278.919651 8854.722007 8207.495524 5571.642364 9786.472191 9452.02667 1.041086355 0.970134089 0.957709634 0.991423814 0.981685725 0.93680671 0.86833182 0.589465366 1.035383472 1 13.20640798 -3.83467518 0.996401634 1.008837864 3.63E-15 0.955297655 0.026446674 0.607062525 0.261341552 0.004620778 0.802147138 0.000146327 3.83467518 -1.008837864 VNHEPEPAGGATPGAT(ph)LPKSPSQLR ddPTM_HeLa_Curcumin_4h_R1 1 VNHEPEPAGGATPGATLPKSPSQLR 25 1 O00499-6;O00499-2;O00499;O00499-11 O00499-6 BIN1 Myc box-dependent-interacting protein 1 1 0 VNHEPEPAGGAT(0.025)PGAT(0.852)LPKS(0.088)PS(0.036)QLR 71.042 0.00056328 119640000 2288.6 1871 2157.7 1989.5 1853.9 2164.5 1469.8 1579.3 2532.3 1999.5 TRUE FALSE FALSE 2107.454895 2032.720903 2237.66626 1981.267976 1831.793453 1715.558301 1511.038632 2060.8213 2254.513026 2068.982476 1.01859485 0.982473717 1.081529827 0.957605006 0.885359579 0.829179716 0.730329353 0.996055464 1.089672364 1 11.01470571 -5.777110338 2.608440585 1.011750107 0.842309982 0.56773701 0.070129603 0.134452665 1.869700081 0.008924171 0.018476146 1.67E-06 5.777110338 -0.169440126 VNHEPEPAGGATPGATLPKS(ph)PSQLR ddPTM_HeLa_Curcumin_4h_R1 1 VNHEPEPAGGATPGATLPKSPSQLR 25 1 O00499-6;O00499-2;O00499;O00499-11 O00499-6 BIN1 Myc box-dependent-interacting protein 1 1 0 VNHEPEPAGGATPGATLPKS(0.631)PS(0.368)QLR 93.126 6.87E-06 125200000 2755.5 1921.2 2498.2 2343.4 2267.4 2597.9 1592.7 1939.4 2936.8 2286.8 TRUE FALSE FALSE 2537.399267 2087.259967 2590.78549 2333.703632 2240.362736 2059.066256 1637.386875 2530.714132 2614.640388 2366.26613 1.072322016 0.882090117 1.094883393 0.986238869 0.946792378 0.870175265 0.691970719 1.069496833 1.104964634 1 11.20839662 -5.564179486 2.207403748 1.025198267 0.860092587 0.285675131 0.103802301 0.250845922 2.444339609 0.013923183 0.03362213 2.73E-06 5.564179486 -0.16510568 VNIAFNYDMPEDSDTYLHR ddPTM_HeLa_Curcumin_4h_R1 2 VNIAFNYDMPEDSDTYLHR 19 0 Q13838-2;Q13838;Q5STU3;H0Y400;A0A140T9X3;A0A0G2JJZ9 Q13838-2 DDX39B Spliceosome RNA helicase DDX39B 0 0 ; ; 124.45 0.00066069 18907400 5472.4 4795.3 4815.4 4292.8 4508.7 9007.3 6436.2 5435.9 6115.4 4795.4 FALSE FALSE TRUE 5039.253766 5209.784365 4993.86296 4275.037531 4454.936697 7139.084447 6616.78245 7093.280886 5444.55592 4962.039793 1.015560934 1.04992797 1.006413324 0.861548417 0.897803501 1.438739862 1.333480328 1.429509069 1.097241487 1 12.27671759 -5.257037306 24.99968389 0.993174347 1.393866834 0.880369415 0.06937252 84.27362333 478593.6417 0.009148471 0.022466468 5.53E-06 5.257037306 0.400692487 VNIFGVESGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VNIFGVESGKK 11 1 H0YMF9;H0YL19;H0YN81;Q9GZS3 H0YMF9 WDR61 "WD repeat-containing protein 61;WD repeat-containing protein 61, N-terminally processed" 0 1 ; VNIFGVESGK(1)K;VNIFGVESGK(1)K 156.51 6.72E-08 817010 589.15 633.25 434.1 462.95 932.847 1136.597 665.9 1060.08 1141.3 544.75 FALSE TRUE FALSE 542.5181558 687.9853083 450.1881279 461.0344356 921.7234088 900.8539701 684.5833618 1383.293512 1016.102245 563.680022 0.962457662 1.220524556 0.798659009 0.817900968 1.635189066 1.598165511 1.214489312 2.454040339 1.80262242 1 9.138732626 -1 0.516320594 0.981080714 47.72882749 0.450693322 0.367719974 40.16111519 0.369331128 0.048138985 2063.886501 0.1 1 46.74774678 VNIIPLIAK ddPTM_HeLa_Curcumin_4h_R1 1 VNIIPLIAK 9 0 G3V1Q4;E7ES33;E7EPK1;Q16181-2;Q16181;A0A0U1RRH9;A0A0U1RRE1;Q6ZU15 G3V1Q4 SEPT7;SEPT14 Septin-7;Septin-14 0 0 107.66 0.00066541 0 710.23 617.99 753.14 696.23 766.55 756.66 702.63 725.77 547.88 687.42 FALSE FALSE TRUE 654.0145461 671.4063019 781.0520309 693.3491847 757.4093919 599.7201867 722.3439068 947.053932 487.7789347 711.3077938 0.919453648 0.943904042 1.098050714 0.974752689 1.064812446 0.843123317 1.015515243 1.331426339 0.685749459 1 9.474330161 -4.275587606 4.264296987 0.970372018 1.354804961 0.504372304 0.112644895 0.078604962 3.255052394 0.009268422 0.089292784 5.30E-05 4.275587606 0.384432944 VNIVPVIAK ddPTM_HeLa_Curcumin_4h_R1 1 VNIVPVIAK 9 0 B5MCX3;Q15019;Q15019-3;Q15019-2;H7C2Y0;C9J2Q4;H7C310 B5MCX3 2-Sep Septin-2 0 0 119.29 7.71E-06 0 1091.4 814.15 941.12 997.84 1202.6 1220.6 1338.7 1120.4 993.17 1044.7 FALSE FALSE TRUE 1005.014538 884.5214982 975.9987351 993.7112025 1188.25978 967.433801 1376.260319 1462.004802 884.2217358 1081.003247 0.929705383 0.818241296 0.902863833 0.919249045 1.099219437 0.894940698 1.273132456 1.352451814 0.817963996 1 10.07815514 -4.695212127 5.228647393 0.953175044 1.328930799 0.773267909 0.083399451 0.06265474 3.207886236 0.010363436 0.040273135 2.02E-05 4.695212127 0.375755754 VNKDDIQK(ac)MNPPK ddPTM_HeLa_Curcumin_4h_R1 1 VNKDDIQKMNPPK 13 2 P35579;Q5BKV1;B1AH99 P35579 MYH9 Myosin-9 0 1 VNKDDIQK(1)MNPPK 133.98 0.00023843 6333400 5619.8 5478.2 5928.4 5770.4 6109.6 6275 5219 4718.9 7053.9 6342.4 FALSE TRUE FALSE 5174.9869 5951.711198 6148.111719 5746.523614 6036.74701 4973.494266 5365.431094 6157.670887 6280.104818 6562.797928 0.788533634 0.906886249 0.936812589 0.875620989 0.919843499 0.757831389 0.817552384 0.938269158 0.95692491 1 12.6800953 -9.533848045 1.28113585 1.000349078 0.858403519 0.333100728 0.060835569 0.363293038 1.063613396 0.044997905 0.010626149 2.93E-10 9.533848045 -0.141945559 LVDVS(ph)PDRGSPPSR ddPTM_HeLa_Curcumin_4h_R1 4 LVDVSPDRGSPPSR 14 1 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 0 LVDVS(0.966)PDRGS(0.033)PPS(0.001)R;LVDVS(1)PDRGSPPSR;LVDVS(1)PDRGSPPSR;LVDVS(0.77)PDRGS(0.23)PPSR ;;; 219.84 4.34E-13 159800000 12187.5 9974.6 10805 11337 10998.8 12386.5 9243.4 4172.48 12663.3 10696.9 TRUE FALSE FALSE 11222.84651 10836.75998 11205.44281 11290.0905 10867.64649 9817.400275 9502.744927 5444.649944 11274.16767 11068.61648 1.013933994 0.979052802 1.012361647 1.020009187 0.981843261 0.886958211 0.858530508 0.491899774 1.018570631 1 13.43418728 -3.986255523 1.110623177 1.004464784 1.02E-15 0.969008696 0.027188616 0.294930747 0.195185972 0.00373941 0.399409449 0.000103215 3.986255523 -1.004464784 down VNNGNTAPEDSS(ph)PAK ddPTM_HeLa_Curcumin_4h_R1 1 VNNGNTAPEDSSPAK 15 0 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 0 VNNGNT(0.048)APEDS(0.305)S(0.647)PAK 115.38 0.0016708 23730000 3837.2 3022.2 3090.5 3418 3295.5 4006 3021.3 1494 3565.6 3581.9 TRUE FALSE FALSE 3533.481571 3283.425501 3205.036649 3403.857222 3256.203315 3175.110443 3106.069547 1949.513722 3174.462601 3706.370758 0.95335351 0.885886954 0.864737194 0.91838012 0.878542253 0.856662933 0.838035304 0.525989937 0.856488141 1 11.85579149 -3.613748935 0.588582412 0.964259936 8.35E-65 0.725436033 0.063048706 2.089336209 0.287706003 0.010351969 1.63006669 0.000243361 3.613748935 -0.964259936 VNNGNTAPEDSS(ph)PAKK ddPTM_HeLa_Curcumin_4h_R1 2 VNNGNTAPEDSSPAKK 16 1 E9PJ27;G3V167;Q9UGN5-2;Q9UGN5 E9PJ27 PARP2 Poly [ADP-ribose] polymerase 2 1 0 VNNGNTAPEDS(0.444)S(0.556)PAKK;VNNGNTAPEDS(0.254)S(0.746)PAKK ; 111.57 0.00070721 82617000 9970.7 7387.8 8905.1 8561.6 8635.7 10046.7 8080 5264.3 9575.4 8962.1 TRUE FALSE FALSE 9181.508574 8026.368513 9235.13084 8526.174368 8532.724918 7962.90117 8306.703054 6869.360836 8525.002576 9273.532308 0.990076733 0.865513619 0.995859025 0.919409572 0.920115942 0.858669696 0.895743151 0.740749114 0.919283213 1 13.17890325 -1.930767691 0.271412452 1.003774575 6.47E-15 0.561602789 0.049380306 10.41921482 0.20768734 0.01871601 4.493080646 0.011728226 1.930767691 -1.003774575 VNPTVFFDIAVDGEPLGR ddPTM_HeLa_Curcumin_4h_R1 1 VNPTVFFDIAVDGEPLGR 18 0 P62937;F8WE65;C9J5S7;E5RIZ5 P62937 PPIA "Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase" 0 0 136.34 0.0024356 8178800 173.82 0 274.42 339.93 216.38 0 0 120.15 0 0 FALSE FALSE TRUE 160.0619636 0 284.5902466 338.5234597 213.7998098 0 0 156.7831819 0 0 0 AESPS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 2 AESPSPPR 8 0 P50219 P50219 MNX1 Motor neuron and pancreas homeobox protein 1 1 0 AES(0.004)PS(0.996)PPR;AESPS(1)PPR ; 121.5 0.0078054 45208000 9507.6 8145.8 8622.7 9275.1 8477.3 10713.6 7343.2 3478.5 10636 8998.7 TRUE FALSE FALSE 8755.063428 8849.886655 8942.264847 9236.722094 8376.213734 8491.478593 7549.230429 4539.078637 9469.25741 9311.404155 0.940251683 0.950435241 0.960356215 0.991979506 0.899565049 0.91194394 0.810751021 0.487475204 1.01695268 1 13.18478303 -3.982823939 1.159362419 0.967033193 6.11E-20 0.958557557 0.030066887 0.368555273 0.264347021 0.004522685 0.501860655 0.000104034 3.982823939 -0.967033193 down SPSEGQTATTS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 SPSEGQTATTSPR 13 0 P25054-2;P25054-3;P25054 P25054-2 APC Adenomatous polyposis coli protein 1 0 SPSEGQTATT(0.027)S(0.973)PR;SPSEGQTATT(0.005)S(0.994)PR ; 129.17 0.0017079 47720000 10068.5 8046.6 8988.4 8754.4 8185.7 9598.6 7028.9 3182.3 10504.2 8761.5 TRUE FALSE FALSE 9271.567601 8742.112249 9321.518011 8718.176612 8088.090874 7607.742161 7226.112017 4152.56862 9351.91554 9065.961473 1.02267891 0.964278557 1.028188575 0.961638392 0.892138236 0.839154477 0.797059643 0.458039518 1.031541505 1 13.14624431 -3.981398279 0.726785521 1.007143948 9.12E-18 0.945678542 0.038748737 0.554735844 0.15692714 0.005989384 0.500743277 0.000104376 3.981398279 -1.007143948 down S(ph)LEGELQR ddPTM_HeLa_Curcumin_4h_R1 1 SLEGELQR 8 0 Q5TZA2-2;Q5TZA2 Q5TZA2-2 CROCC Rootletin 1 0 S(1)LEGELQR 110.53 0.011139 5605800 1668.5 1347.1 1440.5 1541.8 1603.5 1754.1 1342.5 599.85 1862.2 1561.7 TRUE FALSE FALSE 1536.436464 1463.537321 1493.886197 1535.42044 1584.37931 1390.279887 1380.166937 782.7415036 1657.921319 1615.968959 0.950783402 0.90567168 0.924452285 0.950154662 0.980451574 0.860338238 0.854080104 0.484379047 1.025961118 1 10.65818377 -3.977030765 1.257199723 0.963824882 7.59E-16 0.918648724 0.041732053 0.486685759 0.406196045 0.00600724 0.717033017 0.000105431 3.977030765 -0.963824882 down VNQIGSVTESLQACK ddPTM_HeLa_Curcumin_4h_R1 1 VNQIGSVTESLQACK 15 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 0 301.38 4.48E-132 3515900 812.39 596.06 732.3 705.22 967.36 1093.2 910.01 919.76 816.69 763.48 FALSE FALSE TRUE 748.0884743 647.5807704 759.4396822 702.3019865 955.8248638 866.4579971 935.5424314 1200.19059 727.1011503 790.0108732 0.946934403 0.819711212 0.961302823 0.888977621 1.209888239 1.096767179 1.184214627 1.519207685 0.920368535 1 9.625728699 -2.54023789 0.603946898 0.958858332 5.669361557 0.810513404 0.085128989 7.06926964 0.33998194 0.015106255 36.66899979 0.002882452 2.54023789 4.710503226 VNQPASFAVSLNGAK ddPTM_HeLa_Curcumin_4h_R1 1 VNQPASFAVSLNGAK 15 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 163.33 0.00061354 1393600 351.7 630.06 460.25 367.65 595.09 814.12 761.59 363.66 372.6 449.58 FALSE FALSE TRUE 323.8625739 684.5195789 477.3072699 366.1287617 587.9939404 645.262335 782.9581657 474.5382599 331.7267122 465.2028715 0.696174924 1.47144315 1.026019612 0.787030313 1.263951657 1.387055787 1.683046717 1.020067349 0.713079674 1 8.861716192 -5.62275023 4.644356922 0.91469188 1.385777206 0.354025286 0.256633963 0.159958305 5.935324278 0.038105682 0.07806169 2.38E-06 5.62275023 0.471085326 VNQSALEAVTPS(ph)PSFQQR ddPTM_HeLa_Curcumin_4h_R1 4 VNQSALEAVTPSPSFQQR 18 0 Q9UKG1 Q9UKG1 APPL1 DCC-interacting protein 13-alpha 1 0 VNQSALEAVT(0.021)PS(0.978)PSFQQR;VNQSALEAVTPS(0.98)PS(0.02)FQQR;VNQSALEAVT(0.002)PS(0.997)PS(0.001)FQQR;VNQSALEAVT(0.001)PS(0.999)PS(0.001)FQQR ;;; 316.25 1.22E-113 186498000 11193.2 9631.4 9631.1 10725.9 10493.4 13612.2 10698.5 2405.42 12395.4 10139.6 TRUE FALSE FALSE 10307.24641 10463.8953 9988.037038 10681.51907 10368.27306 10788.87628 10998.67112 3138.821485 11035.65563 10491.95035 0.982395653 0.997326041 0.951971436 1.018068016 0.988212174 1.028300356 1.048296147 0.299164729 1.051821184 1 13.35699526 -4.258830157 24.99986274 0.996058709 0.299164482 0.979185114 0.030937404 18.82631397 180370.8555 0.003469158 0.031670993 5.51E-05 4.258830157 -0.696894227 VNSGDT(ph)EVGSSLLR ddPTM_HeLa_Curcumin_4h_R1 2 VNSGDTEVGSSLLR 14 0 A0A499FJI4;O75592-2;O75592 A0A499FJI4 MYCBP2 E3 ubiquitin-protein ligase MYCBP2 1 0 VNS(0.101)GDT(0.899)EVGS(0.001)SLLR;VNS(0.018)GDT(0.682)EVGS(0.276)S(0.024)LLR ; 201.75 1.80E-08 123773000 3472 3023.3 3594.9 3404.1 3430 3380 2325.8 1976.28 3464.4 3050.4 TRUE FALSE FALSE 3197.187536 3284.62058 3728.130156 3390.014736 3389.09949 2678.9499 2391.055688 2578.838674 3084.363988 3156.401173 1.012921793 1.040622025 1.181133181 1.074012634 1.073722668 0.848735554 0.757525916 0.817018666 0.97717743 1 11.62406487 -5.137090008 4.19774639 1.03131015 0.790486244 0.790340386 0.057281955 0.08794551 2.576967169 0.009012826 0.024460854 7.29E-06 5.137090008 -0.240823906 VNSNGKES(ph)PGSSEFFQEAVSHGK ddPTM_HeLa_Curcumin_4h_R1 1 VNSNGKESPGSSEFFQEAVSHGK 23 1 Q8N108-17;Q8N108;Q8N108-13;Q8N108-12 Q8N108-17 MIER1 Mesoderm induction early response protein 1 1 0 VNS(0.002)NGKES(0.557)PGS(0.405)S(0.036)EFFQEAVSHGK 98.957 3.37E-05 16486000 3513.7 3233.8 3246.1 2938.5 3519.3 3774.7 2345.6 3245.5 2747 2576.1 TRUE FALSE FALSE 3235.586937 3513.315262 3366.403322 2926.341266 3477.334646 2991.78467 2411.411223 4235.03801 2445.660973 2665.619283 1.213821853 1.318010897 1.262897272 1.09780916 1.304512864 1.122360079 0.904634521 1.58876327 0.917483224 1 11.38025503 -9.038873866 0.850956475 1.001061615 1.21363379 0.26942714 0.170173263 0.764700377 1.016540757 0.099302479 0.030921029 9.14E-10 9.038873866 0.212572175 VNTLIRPDGEK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VNTLIRPDGEKK 12 2 K7EMA7;H7BY10;K7EJV9;K7ERT8;A8MUS3;P62750 K7EMA7 RPL23A 60S ribosomal protein L23a 0 1 ; VNTLIRPDGEK(1)K;VNTLIRPDGEK(1)K 94.547 0.0034262 31382000 7182.7 10463.1 7235 6675.4 13947.8 19937.2 15218 12794.7 19588.3 7312.4 FALSE TRUE FALSE 6614.181716 11367.48374 7503.135465 6647.778964 13781.48159 15801.99998 15644.97612 16695.74513 17439.5125 7566.505356 0.874139567 1.502342654 0.991624946 0.878579827 1.821380009 2.088414564 2.06766207 2.206533181 2.304830523 1 12.88541142 -5.651699458 3.77110389 0.98577474 2.097156871 0.347023393 0.453593936 0.053496681 1.4410225 0.027700718 0.057501629 2.23E-06 5.651699458 1.111382131 AASSS(ph)SPGS(ph)PVASS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 AASSSSPGSPVASSPSR 17 0 A0A669KB10;A0A669KBG8;Q92538-3;Q92538-2;Q92538 A0A669KB10 GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 3 0 AAS(0.055)S(0.104)S(0.638)S(0.204)PGS(0.998)PVAS(0.047)S(0.633)PS(0.32)R 122.5 0.0013794 5289900 821.33 1029.6 680.93 1082.2 1335 1705.5 1639 2431.9 1101.5 801.51 TRUE FALSE FALSE 756.3208638 1118.594036 706.1658648 1077.722143 1319.080997 1351.760075 1684.985929 3173.375115 980.6682058 829.3624128 0.911930481 1.348739729 0.851456316 1.299458628 1.590475981 1.629878632 2.031664207 3.826282776 1.18243628 1 9.695858855 -1 0.595653853 0.986822511 170.9128619 0.943379283 0.19700408 20.63356879 0.149228291 0.032068051 4571.702805 0.1 1 169.9260394 up VNYDTTESK ddPTM_HeLa_Curcumin_4h_R1 2 VNYDTTESK 9 0 P08621;P08621-2;M0QYR1;P08621-3 P08621 SNRNP70 U1 small nuclear ribonucleoprotein 70 kDa 0 0 ; ; 129.85 0.00063135 5301900 3224.5 2097.1 2822.8 2739.5 2805.8 3756.1 3043.7 3030.5 3144.7 2589.2 FALSE FALSE TRUE 2969.277423 2278.36398 2927.415451 2728.164675 2772.342668 2977.04252 3129.09803 3954.485499 2799.734278 2679.174507 1.108280709 0.850397752 1.092655758 1.018285546 1.03477495 1.111179026 1.167933638 1.476008931 1.044998849 1 11.38757284 -3.768425828 1.101333932 1.036292132 2.271159529 0.800063676 0.0680467 1.471542044 0.677589048 0.010596854 2.746592083 0.000170441 3.768425828 1.234867397 VPAAFPTKVPVPGPGS(ph)GGNGPER ddPTM_HeLa_Curcumin_4h_R1 2 VPAAFPTKVPVPGPGSGGNGPER 23 1 J3KPS2;A0A494C1T9;Q6ZRV2 J3KPS2 FAM83H Protein FAM83H 1 0 VPAAFPTKVPVPGPGS(1)GGNGPER;VPAAFPT(0.001)KVPVPGPGS(0.999)GGNGPER ; 90.268 8.40E-05 86150000 2829.03 1961.21 2162.73 2462.4 2295.97 3716.4 3148 1595.19 2674.16 2999.73 TRUE FALSE FALSE 2605.10929 2130.728253 2242.882676 2452.211241 2268.592057 2945.576748 3236.324408 2081.556088 2380.811338 3103.970394 0.839282905 0.686452505 0.722585074 0.790024043 0.730867814 0.948970632 1.042640231 0.670610806 0.767021278 1 11.59989908 -8.688205979 0.931418249 0.98646666 0.809840052 0 0.13080929 0.51134773 0.890213136 0.049202534 0.023438788 2.05E-09 8.688205979 -0.176626607 VPAINVNDSVTK ddPTM_HeLa_Curcumin_4h_R1 2 VPAINVNDSVTK 12 0 P23526-2;P23526 P23526-2 AHCY Adenosylhomocysteinase 0 0 ; ; 130.1 0.00044808 5785600 3020 2442.01 2946.7 3083.8 2967.7 2979 1859.01 2321.91 2789.93 3124 FALSE FALSE TRUE 2780.963813 2653.086463 3055.907294 3071.040053 2932.312116 2361.12182 1911.168817 3029.84967 2483.881659 3232.558767 0.860297991 0.820738818 0.945352433 0.950033789 0.90711796 0.730418838 0.591224771 0.937291443 0.768394896 1 11.65846088 -2.899227689 0.040268535 1.471244508 4.67E-09 0 0.1225132 420.3401269 1.874484602 22.50180203 51.21697778 0.001261166 2.899227689 -1.471244503 VPAS(ph)PLPGLER ddPTM_HeLa_Curcumin_4h_R1 2 VPASPLPGLER 11 0 E7ETY4;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E9PC69;Q7KZI7-14;Q7KZI7-6;Q7KZI7-10;Q7KZI7-12;Q7KZI7-8;Q7KZI7-11;Q7KZI7-9;Q7KZI7-3;Q7KZI7-4;Q7KZI7-5;Q7KZI7-2;Q7KZI7-7;Q7KZI7 E7ETY4 MARK2 Serine/threonine-protein kinase MARK2 1 0 VPAS(1)PLPGLER;VPAS(1)PLPGLER ; 94.402 0.014506 247500200 4055.92 3103.4 3330.87 4046 3717.74 3286.91 2464.27 1640.72 4163.71 3089.17 TRUE FALSE FALSE 3734.889652 3371.644068 3454.314972 4029.258724 3673.408379 2605.167815 2533.410784 2140.967975 3706.96143 3196.518428 1.168424252 1.05478637 1.080649166 1.26051478 1.149190428 0.815001657 0.792553161 0.669781208 1.159687177 1 11.6422857 -5.154719046 4.030464558 1.097255457 0.746036474 0.824992931 0.076857513 0.087734728 2.487656056 0.012959494 0.0352262 7.00E-06 5.154719046 -0.351218983 VPDEEENEES(ph)DNEKETEK ddPTM_HeLa_Curcumin_4h_R1 3 VPDEEENEESDNEKETEK 18 1 P11388;P11388-2;P11388-3;P11388-4 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 VPDEEENEES(1)DNEKETEK;VPDEEENEES(0.984)DNEKET(0.016)EK;VPDEEENEES(0.995)DNEKET(0.005)EK ;; 115.36 0.00020661 723120000 10053.5 7177.5 10918.7 12606.5 13829.8 8523.4 10012.5 5765.5 8672.4 9292 TRUE FALSE FALSE 9257.754867 7797.891118 11323.35663 12554.33764 13664.88867 6755.550761 10293.4238 7523.374409 7721.059417 9614.896308 0.962855404 0.811021863 1.177688897 1.305717424 1.421220597 0.702612961 1.070570443 0.782470675 0.80303096 1 13.23105558 -1.469887402 8.474933759 1.009908407 0.005093188 0 0.227889354 0 0 0.028135407 0 0.033893202 1.469887402 -1.004815218 VPDVDIK(ac)GPK ddPTM_HeLa_Curcumin_4h_R1 1 VPDVDIKGPK 10 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 1 VPDVDIK(1)GPK 120.68 0.002789 2967700 1832.9 2322.9 1645.1 1794.5 2204.6 3592.6 2307.5 2752.5 4136.1 1543.3 FALSE TRUE FALSE 1687.824031 2523.681125 1706.068853 1787.074834 2178.311585 2847.454263 2372.24224 3591.724579 3682.380178 1596.92956 1.056918272 1.580333403 1.06834321 1.119069293 1.36406241 1.783080691 1.485502115 2.249144025 2.305912715 1 10.64108496 -1 0.318934214 1.011006299 11.9179359 0.02315452 0.452244623 17.17023538 0.218973151 0.064163632 110.6290707 0.1 1 10.9069296 VPEASSEPFDTS(ph)SPQAGR ddPTM_HeLa_Curcumin_4h_R1 1 VPEASSEPFDTSSPQAGR 18 0 H0Y6F5;Q9H4I2 H0Y6F5 ZHX3 Zinc fingers and homeoboxes protein 3 1 0 VPEASSEPFDT(0.007)S(0.969)S(0.024)PQAGR 310.98 2.17E-113 74798000 774.29 622.93 634.34 570.98 831.88 810.98 656 402.79 745.8 584.52 TRUE FALSE FALSE 713.0041295 676.7732935 657.8491984 568.617436 821.9603743 642.7736064 674.4055945 525.5988168 663.9876059 604.8320265 1.17884652 1.118944209 1.087656026 0.940124549 1.358989502 1.062730772 1.11502957 0.868999646 1.097804972 1 9.240390724 -4.258639062 24.11633516 1.097301773 0.868999517 0.310059934 0.10553362 162.2928334 1397532.594 0.014975722 0.137438074 5.51E-05 4.258639062 -0.228302256 VPEASSEPFDTSS(ph)PQAGR ddPTM_HeLa_Curcumin_4h_R1 1 VPEASSEPFDTSSPQAGR 18 0 H0Y6F5;Q9H4I2 H0Y6F5 ZHX3 Zinc fingers and homeoboxes protein 3 1 0 VPEASSEPFDT(0.267)S(0.168)S(0.564)PQAGR 188.16 3.70E-08 77407000 1963.9 1368.3 1393.1 1429.6 1745.3 2038.2 1603.4 1013.3 1869.1 1608.9 TRUE FALSE FALSE 1808.455243 1486.569755 1444.729511 1423.684694 1724.488437 1615.454345 1648.387089 1322.250505 1664.064406 1664.809155 1.086283816 0.892937037 0.867804881 0.855163902 1.035847522 0.970354073 0.990135766 0.794235484 0.999552652 1 10.70114109 -7.256253779 24.96046793 1.040745136 0.92072085 0.345880077 0.070593982 335.3944588 1614395.082 0.01228085 0.014789893 5.54E-08 7.256253779 -0.120024286 VPEEAAQDRPMS(ph)PGDCPPETTETPK ddPTM_HeLa_Curcumin_4h_R1 1 VPEEAAQDRPMSPGDCPPETTETPK 25 1 P13994 P13994 CCDC130 Coiled-coil domain-containing protein 130 1 0 VPEEAAQDRPMS(0.992)PGDCPPET(0.005)T(0.002)ET(0.001)PK 51.554 0.0074857 12035000 820.63 541.69 786.26 533.42 731.12 673.41 360.45 384.92 625.11 651.34 TRUE FALSE FALSE 755.6762696 588.5112699 815.3994873 531.2128494 722.4018715 533.7371751 370.5632569 502.280336 556.5369969 673.9740165 1.121224633 0.873195784 1.209838165 0.788180013 1.071854187 0.791925448 0.549818313 0.745251781 0.825754381 1 9.396549163 -5.09567305 3.313498268 1.036422684 0.647544858 0.46348325 0.139248905 0.108912173 2.250978826 0.016398477 0.048165743 8.02E-06 5.09567305 -0.388877826 VPEPEGQT(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 VPEPEGQTSPK 11 0 Q504Q3-2;Q504Q3-3;Q504Q3 Q504Q3-2 PAN2 PAB-dependent poly(A)-specific ribonuclease subunit PAN2 1 0 VPEPEGQT(0.93)S(0.07)PK 113.95 0.015245 16761000 3029.6 2704.4 2734.3 3092.5 2813.1 3256 3038.6 2638.5 2907.1 2783.6 TRUE FALSE FALSE 2789.803963 2938.156285 2835.635563 3079.704054 2779.55562 2580.668897 3123.854938 3442.966504 2588.198403 2880.329893 0.968570986 1.020076309 0.984482913 1.069219211 0.965012941 0.89596296 1.084547623 1.195337559 0.898577073 1 11.49201834 -4.5109569 4.739665626 0.986923737 1.176205615 0.651365512 0.050584084 0.070374907 4.169246748 0.005739991 0.029027123 3.08E-05 4.5109569 0.189281878 VPEPEGQTS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 VPEPEGQTSPK 11 0 Q504Q3-2;Q504Q3-3;Q504Q3 Q504Q3-2 PAN2 PAB-dependent poly(A)-specific ribonuclease subunit PAN2 1 0 VPEPEGQT(0.029)S(0.971)PK 153.49 0.00047041 31255000 4535 4217.4 4292.3 4289.6 4075.8 5123.7 3746.7 3607.3 4614.2 3769.5 TRUE FALSE FALSE 4176.049965 4581.933264 4451.376414 4271.850772 4027.198747 4060.986864 3851.822318 4707.149164 4108.033804 3900.489844 1.070647568 1.174707138 1.141235227 1.095208792 1.032485382 1.041147914 0.987522714 1.206809747 1.053209717 1 11.9294396 -8.551890997 1.036433899 1.008868727 1.089093991 0.128872995 0.065036375 0.539142761 1.176722678 0.02275272 0.012903485 2.81E-09 8.551890997 0.080225264 VPGEDGTLPPT(ph)QGSPLR ddPTM_HeLa_Curcumin_4h_R1 1 VPGEDGTLPPTQGSPLR 17 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 0 VPGEDGTLPPT(0.943)QGS(0.057)PLR 112.44 0.0029611 15429000 1312 918.78 1165.2 1152.1 1010.6 1152 805.84 471.46 1222.7 1136.3 TRUE FALSE FALSE 1208.153816 998.1952492 1208.383337 1147.332915 998.549255 913.0622143 828.4497016 615.2059837 1088.572869 1175.78634 1.027528365 0.848959726 1.027723571 0.975800514 0.849260806 0.776554535 0.704592045 0.523229402 0.925825409 1 10.19941021 -3.905898856 0.507341314 1.010962657 5.45E-14 0.855975363 0.058541446 1.149599145 0.154510106 0.010483548 0.746447945 0.000124194 3.905898856 -1.010962657 VPGEDGTLPPTQGS(ph)PLR ddPTM_HeLa_Curcumin_4h_R1 3 VPGEDGTLPPTQGSPLR 17 0 Q9Y2F5 Q9Y2F5 ICE1 Little elongation complex subunit 1 1 0 VPGEDGTLPPT(0.074)QGS(0.926)PLR;VPGEDGTLPPT(0.12)QGS(0.88)PLR;VPGEDGTLPPT(0.138)QGS(0.862)PLR ;; 186.17 2.44E-06 104856000 2184 1730.03 1477.96 2027.72 1897.79 2081.92 1451.76 801.82 2204.38 1543.6 TRUE FALSE FALSE 2011.134095 1879.566084 1532.734498 2019.329832 1875.160094 1650.106324 1492.492478 1046.291227 1962.565029 1597.239985 1.259130822 1.176758722 0.959614405 1.264262009 1.17400022 1.033098557 0.934419682 0.655062005 1.228722701 1 10.64136538 -4.320427937 1.439071484 1.129719931 0.500327653 0.703046154 0.098976486 0.546492422 1.091890163 0.017025083 0.476255999 4.78E-05 4.320427937 -0.629392278 VPGGS(ph)PLGVSLVYSDKK ddPTM_HeLa_Curcumin_4h_R1 2 VPGGSPLGVSLVYSDKK 17 1 I3L2J0;A0A0A0MQR4;Q96RK0 I3L2J0 CIC Protein capicua homolog 1 0 VPGGS(1)PLGVSLVYSDKK;VPGGS(1)PLGVSLVYSDKK ; 124.08 0.00022213 69681000 4305 3235.9 3171.3 3716.5 3904.6 5700.1 3857.3 2994.4 4557.4 3559.8 TRUE FALSE FALSE 3964.254707 3515.596777 3288.831168 3701.122108 3858.040195 4517.835007 3965.525457 3907.378775 4057.464622 3683.502785 1.076218735 0.954416756 0.892854264 1.004783306 1.047383542 1.226505115 1.076563719 1.060778016 1.10152343 1 11.84686262 -5.507100311 23.63881358 1.016550753 1.120166091 0.358023459 0.068622575 321.9661001 482359.0979 0.010106974 0.021954237 3.11E-06 5.507100311 0.103615338 VPGPAEGPAEPAAEAS(ph)DEAERR ddPTM_HeLa_Curcumin_4h_R1 2 VPGPAEGPAEPAAEASDEAERR 22 1 H0YFQ2;Q24JP5-4;Q24JP5;Q24JP5-2 H0YFQ2 TMEM132A Transmembrane protein 132A 1 0 VPGPAEGPAEPAAEAS(1)DEAERR;VPGPAEGPAEPAAEAS(1)DEAERR ; 87.419 0.00022532 13848400 1019.32 1071.14 986.57 1081.05 1109.88 1538.04 991.67 663.69 1210.58 1129.85 TRUE FALSE FALSE 938.6397464 1163.724569 1023.133152 1076.576902 1096.645406 1219.033167 1019.493591 866.0460257 1077.782403 1169.112203 0.802865408 0.995391687 0.875136834 0.920849939 0.938015532 1.042699891 0.872023736 0.740772377 0.921881065 1 10.19119768 -9.69388036 1.581265052 0.999867979 0.889783622 0.043619521 0.08570796 0.549181138 2.480151521 0.062221688 0.013847731 2.02E-10 9.69388036 -0.110084357 VPIVINPNAY(ph)DNLAIYK ddPTM_HeLa_Curcumin_4h_R1 2 VPIVINPNAYDNLAIYK 17 0 Q9H792;H0YN99;H3BUZ5 Q9H792 PEAK1 Pseudopodium-enriched atypical kinase 1 1 0 VPIVINPNAY(1)DNLAIYK;VPIVINPNAY(1)DNLAIYK ; 143.55 0.0018931 19189800 3193.8 3102.8 2779.8 2672.9 3365.7 4043.1 2878.3 536.69 2809 2754.3 TRUE FALSE FALSE 2941.00736 3370.992206 2882.821833 2661.840248 3325.566226 3204.515485 2959.057351 700.3243104 2500.859728 2850.01172 1.031928163 1.182799419 1.011512273 0.933975194 1.166860544 1.124386774 1.038261468 0.245726818 0.877491033 1 11.47675214 -4.261458249 11.01773752 1.03949542 0.244682221 0.871687263 0.091512096 0.014085823 93.86032101 0.010760964 0.083040592 5.48E-05 4.261458249 -0.794813199 VPKPEPIPEPKEPS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 3 VPKPEPIPEPKEPSPEK 17 2 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 VPKPEPIPEPKEPS(1)PEK;VPKPEPIPEPKEPS(1)PEK;VPKPEPIPEPKEPS(1)PEK ;; 93.5 0.00099055 4064500000 11351.9 10026.9 11971.4 11671 12728.6 12310.7 12188.3 11830.9 9765.3 9401.6 TRUE FALSE FALSE 10453.38514 10893.58056 12415.07062 11622.70849 12576.81976 9757.32205 12530.27089 15438.08695 8694.071022 9728.3049 1.07453305 1.119781983 1.276180254 1.194731108 1.292806906 1.002982755 1.288022017 1.58692466 0.893688172 1 13.24797273 -1 0.228719608 1.004306725 3.474030716 0.595521126 0.120571648 26.20585421 0.318120075 0.077972451 24.43638819 0.1 1 2.469723991 VPKPEPIPEPKEPS(ph)PEKNSK ddPTM_HeLa_Curcumin_4h_R1 1 VPKPEPIPEPKEPSPEKNSK 20 3 A9Z1X7;Q8IYB3;Q8IYB3-2;E9PCT1;M0R088 A9Z1X7 SRRM1 Serine/arginine repetitive matrix protein 1 1 0 VPKPEPIPEPKEPS(0.932)PEKNS(0.068)K 68.525 0.0036366 0 2329.8 1641.7 1501.6 1980.3 1527.1 1818.6 1385.9 1748.7 2283.4 1730.4 TRUE FALSE FALSE 2145.393872 1783.601233 1557.250617 1972.106043 1508.89033 1441.40186 1424.784624 2281.87058 2032.916733 1790.531271 1.198188441 0.996129619 0.869714281 1.101408322 0.842705377 0.805013508 0.795732891 1.274409789 1.135370694 1 10.806172 -7.009649291 22.23001926 1.0937769 0.936568988 0.19451076 0.145998601 132.9578522 306311.1758 0.024378394 0.0310193 9.78E-08 7.009649291 -0.157207913 VPLAPITDPQQLQLS(ph)PLK ddPTM_HeLa_Curcumin_4h_R1 2 VPLAPITDPQQLQLSPLK 18 0 P31350-2;P31350;A0A286YFD6 P31350-2 RRM2 Ribonucleoside-diphosphate reductase subunit M2 1 0 VPLAPITDPQQLQLS(1)PLK;VPLAPIT(0.001)DPQQLQLS(0.999)PLK ; 210.43 1.18E-12 828000000 3585.6 2706.893 3528.82 3367.54 3530.83 2889.65 2125.39 3016.75 3093 2604.01 TRUE FALSE FALSE 3301.795976 2940.864769 3659.601173 3353.606012 3488.727158 2290.304017 2185.022723 3936.543188 2753.705638 2694.499154 1.225383935 1.091432805 1.35817492 1.244612012 1.294759048 0.84999248 0.810919803 1.460955437 1.021973095 1 11.39580142 -4.209738541 22.67828896 1.114092603 1.460961473 0.274626257 0.174733182 19248.52689 8442477.054 0.025333714 30.8824179 6.17E-05 4.209738541 0.34686887 VPLIFS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 VPLIFSK 7 0 E9PH82 E9PH82 FAM98A 1 0 VPLIFS(1)K 64.803 0.0094387 0 5401.6 4382 5073.2 4741.2 5524.5 7445.7 5091.9 4406.1 5519.8 5047.3 TRUE FALSE FALSE 4974.05766 4760.760554 5261.217255 4721.582171 5458.623946 5901.37789 5234.76501 5749.499607 4914.29175 5222.693299 0.952393215 0.911552772 1.007376262 0.904051205 1.045174134 1.129949157 1.002311396 1.100868705 0.940949711 1 12.35057827 -5.574099138 8.633544993 0.969499947 1.073057133 0.612402134 0.044869061 0.153312863 23.74205456 0.006203611 0.012441835 2.67E-06 5.574099138 0.103557186 VPLRS(ph)S(ph)MLTRNSR ddPTM_HeLa_Curcumin_4h_R1 1 VPLRSSMLTRNSR 13 2 Q9H7U1-2;Q9H7U1;Q9H7U1-3 Q9H7U1-2 CCSER2 Serine-rich coiled-coil domain-containing protein 2 2 0 VPLRS(0.999)S(0.999)MLT(0.001)RNSR 73.273 0.0089914 0 5204.8 7551.5 6021.3 5585.4 5596.1 7502.4 7073.9 5194 7614.3 11123 TRUE FALSE FALSE 4792.834588 8204.218011 6244.454675 5562.289095 5529.370162 5946.317671 7272.374596 6777.62669 6779.03034 11509.52342 0.416423375 0.712819959 0.542546763 0.483277099 0.480416952 0.516643257 0.631857144 0.588871184 0.58899314 1 13.49054048 -9.392728212 0.975461759 1.016350854 0.538775834 0.109585967 0.147915354 0.200317315 0.321763706 0.07043201 0.015706106 4.05E-10 9.392728212 -0.47757502 VPLSNENSQVPQS(ph)PEDWRK ddPTM_HeLa_Curcumin_4h_R1 1 VPLSNENSQVPQSPEDWRK 19 1 Q8IZT6-2;Q8IZT6 Q8IZT6-2 ASPM Abnormal spindle-like microcephaly-associated protein 1 0 VPLSNENS(0.001)QVPQS(0.999)PEDWRK 61.957 0.0091651 20840000 2466.5 2095.1 2371.5 2354.9 2024.1 2604.4 1740.9 1164.5 2733.7 2820.1 TRUE FALSE FALSE 2271.273922 2276.191108 2459.389876 2345.156048 1999.963929 2064.218082 1789.744969 1519.550689 2433.819949 2918.098265 0.778340452 0.780025517 0.842805709 0.803659039 0.685365518 0.707384706 0.613325805 0.520733214 0.834043178 1 11.51081275 -4.092396584 0.097157686 1.204077728 1.47E-17 0.734205299 0.06512424 16.57125735 0.249028292 0.729339269 2.961829252 8.08E-05 4.092396584 -1.204077728 VPLVAEK(ac)PLKEPK ddPTM_HeLa_Curcumin_4h_R1 1 VPLVAEKPLKEPK 13 2 P41250 P41250 GARS Glycine--tRNA ligase 0 1 VPLVAEK(0.918)PLK(0.082)EPK 81.565 0.0077762 2639400 1486.4 1922.3 1583.3 1455.8 2726.8 3087.8 3094.3 2423.3 3254.9 1787.8 FALSE TRUE FALSE 1368.749872 2088.455046 1641.978491 1449.776285 2694.284691 2447.355473 3181.11773 3162.153014 2897.845613 1849.925917 0.739894424 1.128939828 0.887591484 0.78369424 1.456428426 1.322947828 1.719591958 1.70934035 1.566465763 1 10.85325178 -5.363513719 1.196806512 0.886634451 1.720755123 0.446763788 0.264264466 0.163922912 0.427188012 0.025205641 0.102065899 4.33E-06 5.363513719 0.834120672 VPLVAEKPLK(ac)EPK ddPTM_HeLa_Curcumin_4h_R1 1 VPLVAEKPLKEPK 13 2 P41250 P41250 GARS Glycine--tRNA ligase 0 1 VPLVAEK(0.015)PLK(0.985)EPK 94.547 0.0030731 3097300 1492.6 2140.8 1825.3 1621.3 3262.1 3840.4 3375.2 3376.9 3359.3 1511.6 FALSE TRUE FALSE 1374.459135 2325.841213 1892.947224 1614.59149 3223.201588 3043.85775 3469.899028 4406.501265 2990.793195 1564.127987 0.878738278 1.486989064 1.210225275 1.032263026 2.060701946 1.946041356 2.218423975 2.817225508 1.912115389 1 10.61114285 -4.678212663 0.481735856 0.932696858 3.554241111 0.598352873 0.381785838 0.722438336 0.145077573 0.0507811 0.993405295 2.10E-05 4.678212663 2.621544253 VPPAPVPCPPPSPGPSAVPS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 VPPAPVPCPPPSPGPSAVPSSPK 23 0 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 0 VPPAPVPCPPPS(0.079)PGPS(0.174)AVPS(0.374)S(0.374)PK 64.27 0.0018716 21208000 1246.1 1101.5 1196.9 1398.3 1198.8 1526.4 925.18 1090.7 1375.6 1270.8 TRUE FALSE FALSE 1147.46987 1196.708752 1241.258167 1392.514205 1184.505093 1209.807434 951.1380608 1423.249409 1224.700122 1314.960205 0.872627069 0.910072219 0.943951126 1.05897821 0.900791589 0.920033495 0.723320795 1.082351696 0.931359076 1 10.36080342 -9.553141979 1.33344513 0.999839408 0.916744504 0 0.096047447 0.83544558 2.669776844 0.062041348 0.014789731 2.80E-10 9.553141979 -0.083094904 VPPAPVPCPPPSPGPSAVPSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 VPPAPVPCPPPSPGPSAVPSSPK 23 0 O95817 O95817 BAG3 BAG family molecular chaperone regulator 3 1 0 VPPAPVPCPPPS(0.005)PGPS(0.15)AVPS(0.18)S(0.664)PK 48.759 0.015001 26177000 1371.3 1321.4 1241.5 1382.7 1133.5 1232.9 1348.3 729.18 1582.6 1542.6 TRUE FALSE FALSE 1262.760158 1435.615928 1287.511082 1376.978754 1119.983753 977.1826424 1386.129669 951.5036253 1408.992739 1596.205235 0.791101376 0.899393071 0.80660748 0.862657711 0.701653978 0.612191102 0.86839063 0.596103561 0.88271402 1 10.64043045 -13.52287872 0.068259993 1.866044616 0.43379007 0.477506263 0.089094281 123.3975796 0.655591328 17.27961041 2.606597886 3.00E-14 13.52287872 -1.432254546 VPPELLGGS(ph)PPWK ddPTM_HeLa_Curcumin_4h_R1 2 VPPELLGGSPPWK 13 0 E7EVA0 E7EVA0 MAP4 Microtubule-associated protein 1 0 VPPELLGGS(1)PPWK;VPPELLGGS(1)PPWK ; 135.86 0.0012604 939940000 9056.3 7974.6 7856.5 8257.5 7741 10591.3 8138.1 3957.9 9464.5 7951.6 TRUE FALSE FALSE 8339.484299 8663.88889 8147.668801 8223.332653 7648.693631 8394.544991 8366.433183 5164.64549 8426.268029 8227.917508 1.013559542 1.052986844 0.990246778 0.999442768 0.929602615 1.020251477 1.01683484 0.627697772 1.024107014 1 13.00631161 -4.260293169 24.99981535 1.00441164 0.627697652 0.933907425 0.030129001 16.20410574 353380.1553 0.003981955 0.03290929 5.49E-05 4.260293169 -0.376713988 VPQALNFS(ph)PEESDSTFSK ddPTM_HeLa_Curcumin_4h_R1 3 VPQALNFSPEESDSTFSK 18 0 Q9NYZ3 Q9NYZ3 GTSE1 G2 and S phase-expressed protein 1 1 0 VPQALNFS(0.994)PEES(0.004)DS(0.001)TFSK;VPQALNFS(0.986)PEES(0.011)DS(0.002)T(0.001)FSK;VPQALNFS(0.999)PEES(0.001)DSTFSK ;; 165.17 1.77E-05 24007300 4385.8 3793.6 3891 3816.5 4344.5 6605.8 5255.5 1869.96 3945.4 3461.8 TRUE FALSE FALSE 4038.659302 4121.50188 4035.203883 3800.708334 4292.694675 5235.682617 5402.955186 2440.102196 3512.599491 3582.097292 1.127456619 1.150583455 1.126491983 1.061028784 1.198374674 1.461624906 1.50832173 0.681193724 0.980598572 1 11.80658881 -7.862906967 0.391141142 0.994182275 1.223348969 0.090803301 0.213984193 1.906679983 0.780556096 0.172278491 0.113226581 1.37E-08 7.862906967 0.229166694 VPS(ph)PGMEEAGCSR ddPTM_HeLa_Curcumin_4h_R1 4 VPSPGMEEAGCSR 13 0 Q96RL1-2;Q96RL1;Q96RL1-3;Q96RL1-4 Q96RL1-2 UIMC1 BRCA1-A complex subunit RAP80 1 0 VPS(1)PGMEEAGCSR;VPS(1)PGMEEAGCSR;VPS(0.995)PGMEEAGCS(0.005)R;VPS(1)PGMEEAGCSR ;;; 140.31 0.00097987 283193400 1348.25 1324.56 1519.41 1327.21 1597.78 1796.31 1370.22 1058.243 1364.04 1243.57 TRUE FALSE FALSE 1241.53459 1439.049064 1575.720671 1321.718357 1578.727517 1423.735057 1408.664685 1380.896419 1214.408225 1286.783965 0.964835298 1.118329963 1.224541737 1.027148607 1.226878451 1.10642897 1.094717314 1.073137727 0.943754552 1 10.32955415 -7.253075059 19.72634503 0.983394435 1.126664112 0.579826977 0.060068609 17.65521347 41637.05241 0.009206628 0.011136411 5.58E-08 7.253075059 0.143269677 VPS(ph)PGPPTLTSYSVLR ddPTM_HeLa_Curcumin_4h_R1 1 VPSPGPPTLTSYSVLR 16 0 F8W1U0;F8W130;Q12815 F8W1U0 TROAP Tastin 1 0 VPS(1)PGPPTLTSYSVLR 89.232 0.0062946 28759000 613.02 529.67 313.89 462.27 417.39 425.16 347.1 258.8 461.32 578.48 TRUE FALSE FALSE 564.4988201 575.4523146 325.5230395 460.3572492 412.4128969 336.9770235 356.8386918 337.7069286 410.7143502 598.5821369 0.943059917 0.961358983 0.543823511 0.769079498 0.688982967 0.562958703 0.596139894 0.564178093 0.686145351 1 9.225405416 -6.771083259 24.99524682 0.971478923 0.626938595 0.567998642 0.110942012 49.421293 128091.1767 0.010780932 0.014269059 1.69E-07 6.771083259 -0.344540328 VPS(ph)PPDEHQEAENAVSSGNR ddPTM_HeLa_Curcumin_4h_R1 2 VPSPPDEHQEAENAVSSGNR 20 0 Q9BXS6-4;Q9BXS6-6;Q9BXS6-3;Q9BXS6-5;Q9BXS6-2;Q9BXS6;Q9BXS6-7 Q9BXS6-4 NUSAP1 Nucleolar and spindle-associated protein 1 1 0 VPS(1)PPDEHQEAENAVSSGNR;VPS(1)PPDEHQEAENAVSSGNR ; 73.294 0.002241 4473600 1618.63 1451.97 1364.16 1805.51 1894.9 2095.9 1996.89 1315.42 1766.36 1453.42 TRUE FALSE FALSE 1490.513728 1577.471817 1414.71697 1798.039278 1872.304555 1661.186714 2052.917359 1716.485503 1572.594727 1503.926237 0.991081671 1.048902385 0.940682418 1.195563475 1.244944406 1.104566616 1.365038596 1.141336231 1.04565948 1 10.55451809 -6.209074055 6.76239501 0.996804022 1.216007674 0.678106055 0.070480378 0.089126832 9.487568314 0.009167666 0.015212936 6.18E-07 6.209074055 0.219203652 VPS(ph)S(ph)DEEVVEEPQSR ddPTM_HeLa_Curcumin_4h_R1 2 VPSSDEEVVEEPQSR 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 2 0 VPS(1)S(0.994)DEEVVEEPQS(0.006)R;VPS(1)S(1)DEEVVEEPQSR ; 118.08 0.0035035 75336000 1851.01 1393.4 1534.98 1421.66 1183.88 1691.51 1573.99 880.15 1501.8 1091.6 TRUE FALSE FALSE 1704.500605 1513.839287 1591.867709 1415.777548 1169.763004 1340.671759 1618.151923 1148.503683 1337.056297 1129.533019 1.509031234 1.340234647 1.409314896 1.25341847 1.035616476 1.186925691 1.432584879 1.016795139 1.183724845 1 10.14151073 -4.22398671 21.9366354 1.256039279 1.016792229 0.176389958 0.158085684 6793.489071 3978673.28 0.028899212 6.995411037 5.97E-05 4.22398671 -0.23924705 VPS(ph)SDEEVVEEPQSR ddPTM_HeLa_Curcumin_4h_R1 2 VPSSDEEVVEEPQSR 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 VPS(0.96)S(0.04)DEEVVEEPQSR;VPS(0.997)S(0.003)DEEVVEEPQSR ; 180.27 5.74E-05 40941000 711.53 778.37 520.71 573.85 360.337 525.76 501.16 882.33 547.99 704.5 TRUE FALSE FALSE 655.2116497 845.6488345 540.0079707 571.4755608 356.0402166 416.7114495 515.2212008 1151.348355 487.876868 728.9813226 0.89880444 1.16004184 0.740770653 0.783937178 0.488407872 0.57163529 0.706768726 1.57939349 0.669258392 1 9.509738041 -6.720431201 24.99980321 0.966465366 0.780158469 0.025728052 0.300970973 285.8620719 174269.3442 0.043780362 0.061914411 1.90E-07 6.720431201 -0.186306897 VPS(ph)TPPPK ddPTM_HeLa_Curcumin_4h_R1 2 VPSTPPPK 8 0 Q9H7N4 Q9H7N4 SCAF1 "Splicing factor, arginine/serine-rich 19" 1 0 VPS(0.649)T(0.351)PPPK;VPS(0.5)T(0.5)PPPK ; 112.11 0.01068 242380000 14816.3 12242.4 12533.9 13513.7 13370.8 15406.4 12587.4 7489.2 15297.5 12094.5 TRUE FALSE FALSE 13643.57422 13300.5785 12998.41736 13457.78389 13211.36194 12210.93897 12940.56857 9772.622604 13619.40252 12514.78297 1.09019663 1.062789385 1.038645048 1.07535096 1.055660491 0.975721193 1.034022611 0.780886303 1.088265178 1 13.61134565 -3.674294477 1.451880233 1.045809847 9.60E-13 0.832225355 0.035669355 1.912502542 1.079972678 0.005853166 4.424408877 0.000211693 3.674294477 -1.045809847 VPS(ph)VESLFR ddPTM_HeLa_Curcumin_4h_R1 1 VPSVESLFR 9 0 Q13439-3;Q13439-4;Q13439;Q13439-5;Q86W71;E7EVX2 Q13439-3 GOLGA4 Golgin subfamily A member 4 1 0 VPS(0.992)VES(0.008)LFR 117.14 0.006977 86277000 1380.3 892.94 1005.7 1110.6 985.67 1282.3 1195.6 1092.5 1154.6 1185 TRUE FALSE FALSE 1271.047799 970.1217547 1042.972127 1106.004631 973.916529 1016.336526 1229.145318 1425.598221 1027.943269 1226.178662 1.036592658 0.791174879 0.850587406 0.90199305 0.794269676 0.828864958 1.002419432 1.162634994 0.838330743 1 10.25995349 -7.29589382 24.43019916 1.017279878 0.898998731 0 0.119482146 547.4800286 388193.7702 0.018523272 0.02118283 5.06E-08 7.29589382 -0.118281147 VPSPLEGS(ph)EGDGDT(ph)D ddPTM_HeLa_Curcumin_4h_R1 1 VPSPLEGSEGDGDTD 15 0 F5H168;F5H1S9;Q9Y606-2;Q9Y606 F5H168 PUS1 "tRNA pseudouridine synthase;tRNA pseudouridine synthase A, mitochondrial" 2 0 VPS(0.001)PLEGS(0.999)EGDGDT(1)D 135.02 0.0028312 5324700 1883.5 1417.7 1463.4 1324.4 1238.5 1437.1 1068.7 852.78 1401.4 1453.3 TRUE FALSE FALSE 1734.418988 1540.239671 1517.634891 1318.919984 1223.731696 1139.029261 1098.684846 1112.788696 1247.669926 1503.802067 1.153355901 1.024230319 1.009198567 0.877056903 0.813758488 0.757432967 0.730604692 0.739983486 0.829676959 1 10.55439897 -6.061409246 1.258399207 1.072014955 0.740199956 0.614379781 0.085294896 0.113397501 0.355105869 0.009758674 0.02135434 8.68E-07 6.061409246 -0.331815 VPSPLEGSEGDGDT(ph)D ddPTM_HeLa_Curcumin_4h_R1 3 VPSPLEGSEGDGDTD 15 0 F5H168;F5H1S9;Q9Y606-2;Q9Y606 F5H168 PUS1 "tRNA pseudouridine synthase;tRNA pseudouridine synthase A, mitochondrial" 1 0 VPSPLEGSEGDGDT(1)D;VPSPLEGSEGDGDT(1)D;VPSPLEGSEGDGDT(1)D ;; 190.85 7.44E-06 25408200 5473.2 4701.9 4872.1 5376 5182.2 6597.3 4947.5 3924 5734.8 5206 TRUE FALSE FALSE 5039.990445 5108.311285 5052.664312 5353.755536 5120.40565 5228.945613 5086.313534 5120.409536 5105.706788 5386.908112 0.935599854 0.94828261 0.937952571 0.993845713 0.95052775 0.970676593 0.944199052 0.950528472 0.947799124 1 12.39524174 VPSS(ph)DEEVVEEPQSR ddPTM_HeLa_Curcumin_4h_R1 2 VPSSDEEVVEEPQSR 15 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 VPS(0.205)S(0.795)DEEVVEEPQSR;VPS(0.129)S(0.871)DEEVVEEPQSR ; 232.78 4.43E-21 64401000 1040.32 826.35 734.74 1007.15 959.5 1052.85 796.72 1141.42 660.18 900.36 TRUE FALSE FALSE 957.9775743 897.7760119 761.9701107 1002.98268 948.0585892 834.4770419 819.0738189 1489.433704 587.7599057 931.647443 1.028261905 0.96364351 0.817873882 1.076568919 1.017615189 0.895700459 0.879167141 1.598709592 0.630882326 1 9.863640299 -4.255214859 24.91320261 0.987197057 1.598709876 0.66656811 0.136744376 190.0463747 760625.1588 0.010952031 0.136024773 5.56E-05 4.255214859 0.611512819 VPTANVSVVDLTCR ddPTM_HeLa_Curcumin_4h_R1 4 VPTANVSVVDLTCR 14 0 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 ;;; ;;; 172.33 2.95E-05 200135000 2887.76 2422.05 2421.97 2324.8 1918.6 3541.21 2545.8 2277.52 2189.72 2244.6 FALSE FALSE TRUE 2659.190749 2631.40121 2511.730339 2315.180594 1895.721948 2806.723128 2617.228296 2971.925364 1949.513194 2322.599683 1.144919966 1.132955123 1.081430587 0.996805696 0.816206926 1.20844033 1.126852947 1.279568488 0.839366856 1 11.1815248 VPTISINK ddPTM_HeLa_Curcumin_4h_R1 2 VPTISINK 8 0 Q01518-2;Q01518;P40123-3;B7Z385;A0A087X0J3;A0A087WZ15;E9PDI2;P40123-2;P40123 Q01518-2;B7Z385 CAP1;CAP2 Adenylyl cyclase-associated protein 1;Adenylyl cyclase-associated protein 2;Adenylyl cyclase-associated protein 0 0 ; ; 119.27 0.0028042 9720300 8732.9 5995.2 7765.5 7003.5 8397.6 9445.7 7216.6 7211.4 7093.3 6713 FALSE FALSE TRUE 8041.68175 6513.398374 8053.296261 6974.521373 8297.464105 7486.555345 7419.078374 9410.122663 6315.182737 6946.27625 1.157696795 0.937682024 1.159368843 1.004066225 1.194519741 1.077779673 1.068065551 1.354700321 0.909146499 1 12.76202407 VPTTPAS(ph)PVK ddPTM_HeLa_Curcumin_4h_R1 2 VPTTPASPVK 10 0 Q6IE81;Q6IE81-2 Q6IE81 JADE1 Protein Jade-1 1 0 VPT(0.002)T(0.463)PAS(0.536)PVK;VPTT(0.119)PAS(0.881)PVK ; 136.53 0.001996 30135000 9108.5 6906.4 9085.7 8222.1 10944.4 10730.9 8411.1 5286.7 7354.7 7210.3 TRUE FALSE FALSE 8387.552614 7503.358442 9422.424035 8188.079129 10813.89518 8505.190378 8647.092829 6898.590493 6547.907811 7460.857388 1.124207605 1.005696537 1.262914374 1.097471604 1.44941722 1.13997493 1.15899452 0.924637764 0.877634764 1 12.86512572 -8.382876068 0.547648388 1.001571491 1.167088964 0.233039393 0.139361339 1.152874795 0.738563014 0.086498385 0.037934676 4.14E-09 8.382876068 0.165517473 VPTTPAS(ph)PVKNWGGFR ddPTM_HeLa_Curcumin_4h_R1 2 VPTTPASPVKNWGGFR 16 1 Q6IE81;Q6IE81-2 Q6IE81 JADE1 Protein Jade-1 1 0 VPT(0.014)T(0.013)PAS(0.973)PVKNWGGFR;VPT(0.013)T(0.01)PAS(0.977)PVKNWGGFR ; 71.637 0.010017 89509000 7207.7 6025.7 6393.2 6479.9 5408.6 7740.4 5538.9 4049.9 7760.4 7036.2 TRUE FALSE FALSE 6637.202939 6546.534658 6630.137616 6453.087891 5344.105977 6134.953788 5694.306627 5284.695867 6909.103536 7280.707426 0.911615115 0.899161891 0.910644698 0.886327044 0.734009165 0.842631551 0.782108976 0.725849228 0.948960469 1 12.82986292 -1.082405463 0.125287591 1.058228816 4.10E-11 0.794940789 0.039226537 22.61977047 0.196778487 0.140363474 4.207415349 0.082716955 1.082405463 -1.058228816 VPVASPS(ph)AHNISSSGGAPDR ddPTM_HeLa_Curcumin_4h_R1 1 VPVASPSAHNISSSGGAPDR 20 0 E7ETY4;Q7KZI7-15;Q7KZI7-16;Q7KZI7-13;E9PC69;Q7KZI7-14;Q7KZI7-6;Q7KZI7-10;Q7KZI7-12;Q7KZI7-8;Q7KZI7-11;Q7KZI7-9;Q7KZI7-3;Q7KZI7-4;Q7KZI7-5;Q7KZI7-2;Q7KZI7-7;Q7KZI7 E7ETY4 MARK2 Serine/threonine-protein kinase MARK2 1 0 VPVAS(0.017)PS(0.983)AHNISSSGGAPDR 184.21 7.51E-08 5991100 302.62 236.81 199.77 294.61 463.85 758.13 550.28 413.76 381.21 320.66 TRUE FALSE FALSE 278.6673077 257.2788012 207.1736519 293.3909819 458.3188917 600.8852921 565.7193758 539.9135193 339.3922167 331.8029111 0.839857935 0.775396455 0.624387686 0.884232694 1.381298585 1.810970525 1.704986173 1.62721152 1.022872933 1 8.374182734 -5.597273547 3.094454117 0.882015453 1.707474183 0.917500907 0.116504553 0.056518335 1.090407194 0.019517542 0.04264272 2.53E-06 5.597273547 0.82545873 VPVHDVTDASK ddPTM_HeLa_Curcumin_4h_R1 3 VPVHDVTDASK 11 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ;; ;; 130.01 0.0018231 44088400 21301.3 18415.9 18680.7 18493.8 21593.8 25544.5 20301 17705.6 20481.5 18574.2 FALSE FALSE TRUE 19615.27963 20007.68834 19373.02318 18417.27756 21336.30804 20246.28275 20870.59142 23103.95593 18234.73069 19219.65207 1.020584533 1.041001589 1.007979911 0.958252391 1.110129776 1.053415675 1.085898504 1.202100634 0.948754464 1 14.2302946 -1.000000001 0.53327242 1.009483931 8.520621256 0.707963111 0.03874894 39.10532732 0.34303232 0.006044695 335.8076498 0.1 1.000000001 7.511137325 VPVLIS(ph)PTLK ddPTM_HeLa_Curcumin_4h_R1 1 VPVLISPTLK 10 0 P42684-2;P42684-3;P42684-4;P42684-10;P42684-6;P42684;P42684-7;P42684-5 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 0 VPVLIS(0.918)PT(0.082)LK 147.28 0.00099567 37228000 2694.8 2200.8 2195.9 1833.4 2116 2455.7 2365.8 1469.4 1923.8 1724.7 TRUE FALSE FALSE 2481.503736 2391.027345 2277.281986 1825.813877 2090.768082 1946.360139 2432.177981 1917.413296 1712.763953 1784.633197 1.390483905 1.339786433 1.276050446 1.023075151 1.171539387 1.090621951 1.362844749 1.074401899 0.959728843 1 10.80141187 VPVLISPT(ph)LK ddPTM_HeLa_Curcumin_4h_R1 1 VPVLISPTLK 10 0 P42684-2;P42684-3;P42684-4;P42684-10;P42684-6;P42684;P42684-7;P42684-5 P42684-2 ABL2 Abelson tyrosine-protein kinase 2 1 0 VPVLIS(0.352)PT(0.648)LK 166.11 0.0016122 35116000 3505.7 3144.6 3434.8 3543.8 3385.8 3822.3 2935.5 2985.4 3039.9 2653.7 TRUE FALSE FALSE 3228.220146 3416.405212 3562.09671 3529.136695 3345.426546 3029.511894 3017.86223 3895.634717 2706.430575 2745.915877 1.175644226 1.244176939 1.297234463 1.285231177 1.218328126 1.103279208 1.099036665 1.418701406 0.985620353 1 11.42307171 -8.571662877 0.704925772 1.006104584 1.229698149 0.52789053 0.089574758 0.435744328 0.440171784 0.048637172 0.020944186 2.68E-09 8.571662877 0.223593565 VPVPGPGS(ph)GGNGPER ddPTM_HeLa_Curcumin_4h_R1 2 VPVPGPGSGGNGPER 15 0 J3KPS2;A0A494C1T9;Q6ZRV2 J3KPS2 FAM83H Protein FAM83H 1 0 VPVPGPGS(1)GGNGPER;VPVPGPGS(1)GGNGPER ; 110.22 0.0022071 39776000 1586.43 1678.33 2133.63 1801.5 2367.63 2116.32 2160.9 1209.09 1965.69 1646.69 TRUE FALSE FALSE 1460.862392 1823.397367 2212.704205 1794.04587 2339.397559 1677.371376 2221.529038 1577.735975 1750.058725 1703.912355 0.857357708 1.070123919 1.298602125 1.052897976 1.372956509 0.984423507 1.303781284 0.92594902 1.027082596 1 10.73463541 -7.033960267 6.24902877 0.933712002 1.162555501 0.268032058 0.141951599 0.142940896 17.22143582 0.021170299 0.02641011 9.25E-08 7.033960267 0.228843499 VQAGPGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 VQAGPGSPR 9 0 I3L4F6;I3L0U5;Q6PK04 I3L4F6 CCDC137 Coiled-coil domain-containing protein 137 1 0 VQAGPGS(1)PR 89.805 0.01969 336700000 4135.8 3901.5 3915.5 4317.8 4033.1 5066.7 3547 2451.9 4501 3684.6 TRUE FALSE FALSE 3808.447066 4238.728275 4060.611874 4299.934088 3985.007917 4015.809307 3646.519274 3199.473023 4007.251561 3812.639576 0.998900366 1.111756879 1.065039533 1.127810275 1.045209713 1.05328847 0.956429057 0.839175317 1.051043898 1 11.89657444 -4.390664433 2.696685929 1.027367357 0.826825481 0.644142326 0.047019018 0.216558862 2.416341431 0.00786989 0.083385628 4.07E-05 4.390664433 -0.200541875 VQAQGPGLK ddPTM_HeLa_Curcumin_4h_R1 2 VQAQGPGLK 9 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 155.75 5.23E-08 12342600 8194.8 6701.7 7354.6 6476.9 7116.8 9083.5 6668.3 6356.8 8258.1 7267.5 FALSE FALSE TRUE 7546.172933 7280.965086 7627.167946 6450.100304 7031.936808 7199.479708 6855.394551 8294.959057 7352.207091 7520.045084 1.003474427 0.968207638 1.014244976 0.857720962 0.935092374 0.957371881 0.911616151 1.103046453 0.977681252 1 12.8765256 VQAQVIQETIVPK ddPTM_HeLa_Curcumin_4h_R1 1 VQAQVIQETIVPK 13 0 Q15459 Q15459 SF3A1 Splicing factor 3A subunit 1 0 0 135.99 0.00089874 527660 153.09 67.509 128.6 144.38 0 148.17 141.09 0 133.37 124.18 FALSE FALSE TRUE 140.972765 73.34417715 133.3660291 143.7825938 0 117.4378718 145.0486057 0 118.7396447 128.4952458 1.097104909 0.570792925 1.037906331 1.118972091 0 0.913947213 1.128824688 0 0.924078116 1 7.005571171 -4.250067164 0.305395752 1.064096098 6.79E-13 0.178147099 0.379383919 9.185202818 0.621297962 0.162301787 3.648890317 5.62E-05 4.250067164 -1.064096098 VQAYEEPSVAS(ph)SPNGK ddPTM_HeLa_Curcumin_4h_R1 3 VQAYEEPSVASSPNGK 16 0 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 0 VQAYEEPSVAS(0.996)S(0.004)PNGK;VQAYEEPS(0.001)VAS(0.5)S(0.5)PNGK;VQAYEEPSVAS(0.5)S(0.5)PNGK ;; 262.24 1.16E-51 578028000 23992.5 22462.9 23818.2 23672.6 24177.3 26508.5 19980.6 16467.3 23139.7 19069.1 TRUE FALSE FALSE 22093.46831 24404.49298 24700.92344 23574.64905 23889.00149 21010.33829 20541.20186 21488.10396 20601.3328 19731.74981 1.119691286 1.236813421 1.251836441 1.194757144 1.210688445 1.064798535 1.041022822 1.089011577 1.044070242 1 14.26823128 -8.534550241 0.974282343 1.014085966 1.152448229 0.348666641 0.069879694 0.405839836 0.78638528 0.029048865 0.016110362 2.92E-09 8.534550241 0.138362262 VQAYEEPSVAS(ph)SPNGKESDLR ddPTM_HeLa_Curcumin_4h_R1 2 VQAYEEPSVASSPNGKESDLR 21 1 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 0 VQAYEEPS(0.164)VAS(0.406)S(0.406)PNGKES(0.023)DLR;VQAYEEPS(0.007)VAS(0.471)S(0.471)PNGKES(0.051)DLR ; 81.297 0.0004803 142397000 7138.9 5251.4 5392.4 6169.8 4468 6804.7 4744.8 4335.4 8717.4 6455.4 TRUE FALSE FALSE 6573.848532 5705.307616 5592.247088 6144.271002 4414.722018 5393.328515 4877.926318 5657.243502 7761.12303 6679.72467 0.984149626 0.854123171 0.837197245 0.919838961 0.660913771 0.807417788 0.73025859 0.846927648 1.161892655 1 12.70557292 -6.855522983 0.873958525 0.99919853 0.772383335 0.639353292 0.081810458 0.207421116 0.316429819 0.012577613 0.018995091 1.39E-07 6.855522983 -0.226815195 VQAYEEPSVAS(ph)SPNGKESDLRR ddPTM_HeLa_Curcumin_4h_R1 1 VQAYEEPSVASSPNGKESDLRR 22 2 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 0 VQAYEEPS(0.115)VAS(0.369)S(0.369)PNGKES(0.148)DLRR 51.473 0.018076 12939000 1490.5 1021.2 1140.7 1141 1220.4 1292.8 974.18 904.3 1911.9 1620.3 TRUE FALSE FALSE 1372.525352 1109.467978 1182.975345 1136.278844 1205.847527 1024.658707 1001.512869 1180.016907 1702.169353 1676.605304 0.81863355 0.661734741 0.705577718 0.677725903 0.719219678 0.61115082 0.59734564 0.703813178 1.015247506 1 10.71132738 -7.920730525 0.482058187 1.004804494 0.63712563 0.904466808 0.043514723 0.176954897 0.100699823 0.025787907 0.016739939 1.20E-08 7.920730525 -0.367678863 VQAYEEPSVASS(ph)PNGK ddPTM_HeLa_Curcumin_4h_R1 2 VQAYEEPSVASSPNGK 16 0 Q99575 Q99575 POP1 Ribonucleases P/MRP protein subunit POP1 1 0 VQAYEEPSVAS(0.371)S(0.629)PNGK;VQAYEEPSVAS(0.404)S(0.596)PNGK ; 132.15 0.00045152 20650000 6951.73 6771.4 6337.53 7219.58 7008.72 8001.62 6112.1 5246.35 7342.15 6648.24 TRUE FALSE FALSE 6401.493235 7356.689643 6572.404437 7189.707291 6925.145592 6341.993815 6283.589076 6845.937964 6536.734514 6879.265845 0.930548896 1.0694004 0.955393291 1.045127119 1.006669279 0.921899801 0.913409834 0.995155314 0.950208156 1 12.74803889 -5.256003729 24.8609928 0.981722523 0.940480469 0.168794122 0.045865547 690.6066986 3158603.168 0.006866637 0.01698804 5.55E-06 5.256003729 -0.041242054 DTYS(ph)DRSGSSS(ph)PDSEITELK ddPTM_HeLa_Curcumin_4h_R1 1 DTYSDRSGSSSPDSEITELK 20 1 B4E1E0;P17812-2;P17812 B4E1E0 CTPS1 CTP synthase;CTP synthase 1 2 0 DT(0.042)Y(0.024)S(0.788)DRS(0.14)GS(0.013)S(0.316)S(0.674)PDS(0.002)EIT(0.001)ELK 87.457 0.0011555 7683100 2602.7 2303.7 2644.8 2986.4 2950.6 3972.7 3504.1 3874.2 2938.9 2439.2 TRUE FALSE FALSE 2396.693549 2502.821563 2742.818615 2974.043068 2915.416022 3148.717238 3602.415615 5055.425745 2616.510023 2523.962018 0.949575917 0.991624099 1.086711525 1.178323226 1.155095045 1.247529565 1.427285985 2.002972195 1.036667748 1 11.30147448 -1 0.522552451 0.982313501 38.20590143 0.966048119 0.054853872 12.5241659 0.11322444 0.01102759 520.031958 0.1 1 37.22358792 up VQDLSAGGQGSLTDSGPERRPEGPGAQAPS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 2 VQDLSAGGQGSLTDSGPERRPEGPGAQAPSSPR 33 2 P40222 P40222 TXLNA Alpha-taxilin 1 0 VQDLSAGGQGS(0.004)LT(0.014)DS(0.089)GPERRPEGPGAQAPS(0.446)S(0.446)PR;VQDLSAGGQGSLT(0.002)DS(0.005)GPERRPEGPGAQAPS(0.496)S(0.496)PR ; 50.487 0.0026186 168330000 3708.4 3093.1 2631.6 3741.3 2612.1 4443.1 3402 4558.5 5103.3 4017.7 TRUE FALSE FALSE 3414.876227 3360.453781 2729.129411 3725.819492 2580.952414 3521.550976 3497.450964 5948.365665 4543.480758 4157.314776 0.82141392 0.808323151 0.656464463 0.896208176 0.620821985 0.847073451 0.841276437 1.430819167 1.092888319 1 12.02143627 -4.260248182 24.47278468 0.860414073 1.430819417 0.633323598 0.133636912 37.86025626 777694.7749 0.018201976 0.150473289 5.49E-05 4.260248182 0.570405343 VQDPPGTSTDCYLLPVLK ddPTM_HeLa_Curcumin_4h_R1 1 VQDPPGTSTDCYLLPVLK 18 0 Q9BZA0 Q9BZA0 TTTY10 Putative transcript Y 10 protein 0 0 42.818 0.019989 68272000 2955.7 5178.3 4224.4 3219.5 3660.1 9913.9 7633.9 4506.7 5262.8 6086 FALSE FALSE TRUE 2721.753226 5625.889178 4380.95998 3206.178562 3616.455698 7857.645387 7848.086688 5880.772084 4685.484007 6297.488047 0.432196648 0.893354483 0.695667852 0.50912023 0.574269561 1.247742803 1.246224944 0.933828225 0.74402428 1 12.62056076 -5.258259498 24.99611085 0.709517664 1.152961304 0.568736068 0.179057984 207.1045449 1627977.427 0.033784053 0.082323034 5.52E-06 5.258259498 0.44344364 VQDTS(ph)NTGLGEDIIHQLSK ddPTM_HeLa_Curcumin_4h_R1 4 VQDTSNTGLGEDIIHQLSK 19 0 Q8IWA0 Q8IWA0 WDR75 WD repeat-containing protein 75 1 0 VQDT(0.139)S(0.642)NT(0.22)GLGEDIIHQLSK;VQDT(0.158)S(0.809)NT(0.033)GLGEDIIHQLSK;VQDT(0.137)S(0.441)NT(0.422)GLGEDIIHQLSK;VQDT(0.23)S(0.733)NT(0.037)GLGEDIIHQLSK ;;; 144.83 6.77E-05 237708000 12936.8 10693.96 12990.32 13436.6 14364.2 18163.9 13621.3 10313.26 13632.8 12959.6 TRUE FALSE FALSE 11912.83863 11618.29825 13471.75269 13381.00291 14192.9163 14396.50239 14003.47702 13457.7255 12137.31595 13409.94514 0.888358491 0.866394167 1.004609083 0.997841734 1.05838735 1.073569075 1.044260575 1.003563054 0.905098106 1 13.71101571 -6.308754753 2.223503603 0.940300317 1.043637953 0.612176477 0.042986314 0.222679057 2.152154099 0.008606816 0.014524945 4.91E-07 6.308754753 0.103337636 VQEHEDS(ph)GDS(ph)EVENEAK ddPTM_HeLa_Curcumin_4h_R1 4 VQEHEDSGDSEVENEAK 17 0 Q9Y5J1 Q9Y5J1 UTP18 U3 small nucleolar RNA-associated protein 18 homolog 2 0 VQEHEDS(1)GDS(1)EVENEAK;VQEHEDS(1)GDS(1)EVENEAK;VQEHEDS(1)GDS(1)EVENEAK;VQEHEDS(1)GDS(1)EVENEAK ;;; 155.88 3.75E-06 246070000 12569.3 10381.8 11510.9 12497.8 11766.2 14397.1 10936.9 8898.4 13351.8 11002.3 TRUE FALSE FALSE 11574.42664 11279.15653 11937.50408 12446.08742 11625.89575 11410.97917 11243.75998 11611.4812 11887.14094 11384.62911 1.016671385 0.990735528 1.048563284 1.09323609 1.021192315 1.00231453 0.987626375 1.019926173 1.0441395 1 13.47479967 -2.861568566 10.23646035 1.014602762 8.253465574 0 0.031538212 0 0 0.00420202 0 0.001375408 2.861568566 7.238862812 VQEHEDS(ph)GDSEVENEAK ddPTM_HeLa_Curcumin_4h_R1 2 VQEHEDSGDSEVENEAK 17 0 Q9Y5J1 Q9Y5J1 UTP18 U3 small nucleolar RNA-associated protein 18 homolog 1 0 VQEHEDS(0.999)GDS(0.001)EVENEAK;VQEHEDS(0.996)GDS(0.004)EVENEAK ; 158.91 7.31E-05 125225000 11631.8 8962.7 8294.4 8255.5 9777 10395.5 6855.5 6072.8 11327 7707.4 TRUE FALSE FALSE 10711.13076 9737.395851 8601.79776 8221.340928 9660.415661 8239.356119 7047.846879 7924.368764 10084.45644 7975.231576 1.343049497 1.220954622 1.078564011 1.030859211 1.211302213 1.033118103 0.883716894 0.993622403 1.264471927 1 12.9613107 -5.034474667 4.319979323 1.155993702 0.940190358 0.441676442 0.103156754 0.193159703 8.196448458 0.01965015 0.056369591 9.24E-06 5.034474667 -0.215803344 VQEKPDSPGGS(ph)TQIQR ddPTM_HeLa_Curcumin_4h_R1 1 VQEKPDSPGGSTQIQR 16 1 M0R0P8;Q13459-2;Q13459;M0R300 M0R0P8 MYO9B Unconventional myosin-IXb 1 0 VQEKPDS(0.231)PGGS(0.603)T(0.166)QIQR 92.133 0.0021645 38899000 3644.5 3059 3263.5 3737.9 2576.9 3695.5 2947.1 5656.2 3956.1 3549.9 TRUE FALSE FALSE 3356.033979 3323.406329 3384.448181 3722.43356 2546.172151 2929.011643 3029.787694 7380.749342 3522.125728 3673.258761 0.913639413 0.904756933 0.921374834 1.013387241 0.693164385 0.797387779 0.824822832 2.009319197 0.958855871 1 11.84284481 -4.258372362 24.99905368 0.920671037 2.009319595 0.92324982 0.096330486 61.57365993 501857.6523 0.014683455 0.138589524 5.52E-05 4.258372362 1.088648558 VQESTKGPDEAK ddPTM_HeLa_Curcumin_4h_R1 2 VQESTKGPDEAK 12 1 O43390;B4DT28;O43390-4;O43390-3;O43390-2 O43390 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 0 ; ; 120.03 0.00052165 10935400 7904.2 6183.5 6830.6 6941.9 7079 8312.2 6712.1 5596.2 8088 7030.8 FALSE FALSE TRUE 7278.57423 6717.974187 7083.748045 6913.176257 6994.587548 6588.156022 6900.423461 7302.455618 7200.766635 7275.119777 1.000474831 0.923417675 0.97369504 0.950249133 0.961439504 0.905573547 0.9484962 1.003757442 0.989779805 1 12.82875529 -7.284931133 24.03016475 1.000224231 0.951513041 0.392381114 0.025178837 301.5083661 308417.667 0.004072595 0.004658775 5.19E-08 7.284931133 -0.048711189 VQESTKGPDEAK(ac)IK ddPTM_HeLa_Curcumin_4h_R1 1 VQESTKGPDEAKIK 14 2 O43390;B4DT28;O43390-4;O43390-3;O43390-2 O43390 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 1 VQESTKGPDEAK(1)IK 121.18 0.0002326 51778000 5051.9 4221.3 4393.1 5309 4723.2 7296.6 5651.6 5348.8 6019.5 5884.8 FALSE TRUE FALSE 4652.036784 4586.170362 4555.912151 5287.032765 4666.878925 5783.20291 5810.168685 6979.624497 5359.17591 6089.296362 0.763969514 0.75315276 0.748183678 0.868250197 0.766406929 0.949732542 0.954160931 1.146211989 0.880097731 1 12.57205981 -4.23902531 1.379530142 0.857592568 1.272850056 0.574469779 0.081347682 1.093903192 1.737018614 0.016300258 0.639006357 5.77E-05 4.23902531 0.415257488 VQFQGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VQFQGKK 7 1 P05455 P05455 SSB Lupus La protein 0 1 ; VQFQGK(1)K;VQFQGK(1)K 107.32 0.0052771 52275000 9801.1 5592.9 9618 6795.4 8539.7 11259.2 11547.4 11496.3 8232.6 7577.1 FALSE TRUE FALSE 9025.332593 6076.325355 9974.451541 6767.282435 8437.869655 8923.915003 11871.38897 15001.46895 7329.504377 7840.403661 1.151131113 0.775001597 1.272185971 0.86312934 1.076203474 1.138195862 1.514129818 1.913354158 0.93483763 1 12.93671222 -4.495130978 1.723785391 1.049157123 2.017087346 0.817394767 0.136851618 0.170552796 0.692847361 0.018021025 0.232403241 3.20E-05 4.495130978 0.967930223 VQGEAVSNIQENTQTPTVQEES(ph)EEEEVDETGVEVK ddPTM_HeLa_Curcumin_4h_R1 1 VQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVK 35 0 F8VZJ2;F8W0W4;H0YHX9;Q13765;E9PAV3-2;E9PAV3 F8VZJ2 NACA "Nascent polypeptide-associated complex subunit alpha;Nascent polypeptide-associated complex subunit alpha, muscle-specific form" 1 0 VQGEAVSNIQENTQT(0.001)PT(0.154)VQEES(0.841)EEEEVDET(0.004)GVEVK 122.81 1.51E-18 20782000 3534.2 3783.4 3693.9 3539.2 3972 5013.3 3733.4 3834.6 3855.2 3194.6 TRUE FALSE FALSE 3254.464341 4110.420237 3830.799183 3524.555728 3924.636494 3973.485068 3838.149156 5003.751888 3432.294205 3305.612112 0.984526989 1.2434672 1.158877404 1.06623391 1.187264676 1.202042143 1.161100887 1.513714168 1.038323339 1 11.69070173 -1 0.249411018 0.979079268 3.682621527 0.621067269 0.090131709 20.59099329 0.25677811 0.049935095 23.61395278 0.1 1 2.70354226 VQGLLENGDSVT(ph)SPEK ddPTM_HeLa_Curcumin_4h_R1 1 VQGLLENGDSVTSPEK 16 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 0 VQGLLENGDSVT(0.996)S(0.004)PEK 159.14 0.00079684 9555400 3064.9 2992 3510.7 2782.1 3628.5 3579.6 2430.5 1366.8 3056.2 2606.4 TRUE FALSE FALSE 2822.309931 3250.615148 3640.80963 2770.588407 3585.232507 2837.15061 2498.693289 1783.531028 2720.942506 2696.972206 1.046473495 1.205283147 1.349961865 1.027295869 1.329354637 1.051976214 0.926480919 0.661308642 1.008887856 1 11.39712494 -4.380413616 2.232715865 1.082720617 0.611022289 0.544766896 0.128379989 0.331500106 2.269088151 0.019906691 0.276603062 4.16E-05 4.380413616 -0.471698328 VQGLLENGDSVTS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 1 VQGLLENGDSVTSPEK 16 0 P41229-4;P41229-3;P41229-2;P41229-5;P41229 P41229-4 KDM5C Lysine-specific demethylase 5C 1 0 VQGLLENGDS(0.002)VT(0.187)S(0.811)PEK 106.6 0.0018851 8396000 2231.7 2172.8 2479.3 2179.8 2356.6 2644.3 1781.9 993.32 1998.2 1765.9 TRUE FALSE FALSE 2055.05859 2360.60715 2571.185039 2170.780565 2328.499084 2095.842373 1831.895318 1296.178695 1779.002459 1827.264894 1.124663751 1.291880098 1.407122223 1.187994457 1.274308444 1.14698333 1.002534074 0.709354566 0.973587609 1 10.83547008 -4.326383051 2.485984414 1.130557575 0.648898377 0.528495051 0.130061366 0.33648475 2.833695661 0.021357689 0.320393278 4.72E-05 4.326383051 -0.481659198 VQGSDS(ph)DEEVVVATTR ddPTM_HeLa_Curcumin_4h_R1 2 VQGSDSDEEVVVATTR 16 0 A0A140T936;P26640-2;P26640 A0A140T936 VARS Valine--tRNA ligase 1 0 VQGS(0.021)DS(0.979)DEEVVVATTR;VQGS(0.068)DS(0.932)DEEVVVATTR ; 126.25 0.00055207 8937400 1886.78 1547.6 1452.58 1923.42 1501.77 2123.88 1735.99 3110.1 2077.29 1956.76 TRUE FALSE FALSE 1737.439372 1681.367648 1506.413893 1915.461398 1483.862374 1683.363347 1784.697207 4058.355173 1849.416484 2024.757264 0.858097611 0.830404552 0.743997278 0.946020262 0.73285939 0.8313902 0.881437612 2.004366274 0.91340158 1 10.98353325 -4.261157335 24.99999999 0.890479266 2.004366606 0.943474212 0.083747741 4.488225277 397628.4719 0.013874952 0.108915893 5.48E-05 4.261157335 1.11388734 VQIPVSRPDPEPVS(ph)DNEEDS(ph)YDEEIHDPR ddPTM_HeLa_Curcumin_4h_R1 2 VQIPVSRPDPEPVSDNEEDSYDEEIHDPR 29 1 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 2 0 VQIPVS(0.004)RPDPEPVS(0.989)DNEEDS(0.54)Y(0.466)DEEIHDPR;VQIPVS(0.009)RPDPEPVS(0.964)DNEEDS(0.548)Y(0.479)DEEIHDPR ; 62.717 0.0010219 238410000 2465.3 2376.5 2115.28 2792.58 2707.1 2979.5 2318.2 2223.1 2611.5 2485 TRUE FALSE FALSE 2270.168904 2581.914071 2193.674138 2781.025044 2674.819601 2361.518114 2383.242453 2900.912956 2325.024984 2571.353565 0.882869215 1.004106983 0.853120383 1.081541287 1.040237965 0.918394944 0.926843545 1.128165724 0.904202757 1 11.32831228 -6.252279073 24.99897849 0.942441703 1.009501486 0.254719915 0.07446702 1011.961673 2761696.265 0.011705631 0.019233135 5.59E-07 6.252279073 0.067059783 VQIPVSRPDPEPVSDNEEDS(ph)YDEEIHD ddPTM_HeLa_Curcumin_4h_R1 1 VQIPVSRPDPEPVSDNEEDSYDEEIHD 27 1 H0YLT6 H0YLT6 TJP1 1 0 VQIPVSRPDPEPVS(0.008)DNEEDS(0.53)Y(0.462)DEEIHD 50.158 0.008032 5820100 605.43 473.09 697.07 763.34 825.01 788.12 666.91 816.06 720.89 627 TRUE FALSE FALSE 557.5095767 513.9817916 722.9040274 760.1815013 815.1722946 624.6550281 685.6216997 1064.872937 641.8101706 648.7882033 0.859309053 0.792218152 1.114237318 1.171694395 1.256453632 0.962802691 1.056772759 1.641325986 0.989244514 1 9.341603778 -6.58777682 5.662517589 0.921378499 1.192147268 0.401419808 0.175753528 0.166711306 10.24871418 0.027167873 0.038699472 2.58E-07 6.58777682 0.270768769 VQIPVSRPDPEPVSDNEEDS(ph)YDEEIHDPR ddPTM_HeLa_Curcumin_4h_R1 2 VQIPVSRPDPEPVSDNEEDSYDEEIHDPR 29 1 A0A087X0K9;G5E9E7;Q07157-2;H0YKB1;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 0 VQIPVSRPDPEPVS(0.01)DNEEDS(0.769)Y(0.221)DEEIHDPR;VQIPVSRPDPEPVS(0.011)DNEEDS(0.532)Y(0.458)DEEIHDPR ; 77.907 8.31E-06 115291000 5705.6 4792.5 4691.9 4826.5 4842.1 5423.8 4165.3 6503.8 5313.2 5236.4 TRUE FALSE FALSE 5253.995739 5206.742345 4865.785941 4806.529222 4784.36112 4298.842741 4282.167108 8486.77868 4730.355253 5418.36451 0.969664505 0.960943535 0.898017461 0.887081187 0.882989897 0.793383821 0.790306208 1.566298957 0.873022707 1 12.40364174 -4.252820861 24.96864804 0.941909055 1.566299277 0.860187748 0.079183205 351.881759 1019411.719 0.012634588 0.198270297 5.59E-05 4.252820861 0.624390223 VQIS(ph)PDSGGLPER ddPTM_HeLa_Curcumin_4h_R1 1 VQISPDSGGLPER 13 0 A0A087WTP3;Q92945;M0QXW7;M0QYH3 A0A087WTP3 KHSRP Far upstream element-binding protein 2 1 0 VQIS(0.895)PDS(0.105)GGLPER 158.91 0.00029908 111790000 2609 2118 2323.7 2298 2214.6 2660.9 1852.1 2714.5 2694.6 2113.3 TRUE FALSE FALSE 2402.494897 2301.070482 2409.818366 2288.491485 2188.192341 2108.999345 1904.064941 3542.138554 2399.009122 2186.737018 1.098666587 1.052284963 1.102015627 1.046532558 1.000665523 0.964450379 0.870733392 1.619828322 1.097072534 1 11.09456401 -4.251476774 24.9993583 1.034199916 1.619828639 0.870690844 0.068605812 377.2043319 946507.5306 0.009919526 0.180522069 5.60E-05 4.251476774 0.585628723 VQISPDS(ph)GGLPER ddPTM_HeLa_Curcumin_4h_R1 2 VQISPDSGGLPER 13 0 A0A087WTP3;Q92945;M0QXW7;M0QYH3 A0A087WTP3 KHSRP Far upstream element-binding protein 2 1 0 VQIS(0.339)PDS(0.661)GGLPER;VQIS(0.232)PDS(0.768)GGLPER ; 135.86 0.0012604 42441000 3301.96 2135.01 2723.94 3249.36 2953.6 3529.02 2696.89 3452.03 3007.4 2441.48 TRUE FALSE FALSE 3040.606382 2319.550751 2824.891613 3235.915009 2918.380249 2797.061472 2772.557475 4504.538056 2677.495744 2526.321248 1.203570759 0.918153522 1.118183847 1.280880257 1.155189686 1.107167774 1.097468296 1.783042461 1.059839775 1 11.30282239 -4.261075009 25 1.104582975 1.783042665 0.819325896 0.09559191 10.17965175 698170.6712 0.014794796 0.116510122 5.48E-05 4.261075009 0.678459689 TEIMS(ph)PLYQDEAPK ddPTM_HeLa_Curcumin_4h_R1 4 TEIMSPLYQDEAPK 14 0 Q8IY81 Q8IY81 FTSJ3 pre-rRNA processing protein FTSJ3 1 0 TEIMS(0.997)PLY(0.003)QDEAPK;T(0.028)EIMS(0.972)PLYQDEAPK;T(0.001)EIMS(0.998)PLY(0.002)QDEAPK;TEIMS(0.834)PLY(0.166)QDEAPK ;;; 133.48 0.0011405 72199900 13075.5 13222.3 13432.9 13675.8 16051.6 18946.2 16061 15917.9 13645.8 9863.8 TRUE FALSE FALSE 12040.56038 14365.17669 13930.73509 13619.21316 15860.19515 15016.54455 16511.62843 20771.19443 12148.88988 10206.56632 1.179687664 1.407444605 1.364879692 1.334357975 1.553920747 1.471263115 1.617745667 2.035081514 1.190301371 1 13.31720998 -1 0.178265617 0.940444584 5.032921694 0.83877984 0.108873115 11.8871142 0.12835928 0.122508009 13.2208076 0.1 1 4.09247711 up TPT(ph)SPLEELTSLFSSGR ddPTM_HeLa_Curcumin_4h_R1 1 TPTSPLEELTSLFSSGR 17 0 Q9P242;Q9P242-3 Q9P242 NYAP2 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 1 0 T(0.071)PT(0.634)S(0.294)PLEELT(0.001)SLFSSGR 153.92 0.00054173 67264000 389.85 299.94 324.93 365.67 476.94 677.29 536.22 600.77 527.16 284.75 TRUE FALSE FALSE 358.9929611 325.8654771 336.9721916 364.1569544 471.252802 536.8124194 551.26489 783.9420074 469.3318669 294.6450413 1.218391321 1.105959481 1.143654718 1.235917471 1.599391593 1.821895312 1.870945758 2.660631938 1.592872104 1 8.202834176 -1 0.3841311 1.064560436 24.27730996 0.837217669 0.192728951 8.371361349 0.101099249 0.027879615 146.8813654 0.1 1 23.21274952 up VQNHLPASGPTQPPVVS(ph)STNEGSPSPPEPTGK ddPTM_HeLa_Curcumin_4h_R1 1 VQNHLPASGPTQPPVVSSTNEGSPSPPEPTGK 32 0 O43294;H3BQC4;O43294-2 O43294 TGFB1I1 Transforming growth factor beta-1-induced transcript 1 protein 1 0 VQNHLPASGPTQPPVVS(0.72)S(0.187)T(0.011)NEGS(0.074)PS(0.007)PPEPTGK 113.79 2.89E-12 42712000 4316.7 4438.2 3723.6 4630.4 4446.3 6798.8 4000.7 2358.1 5157.3 3803.5 TRUE FALSE FALSE 3975.02864 4821.818232 3861.599892 4611.240632 4393.280776 5388.652242 4112.948875 3077.073835 4591.557093 3935.671342 1.010000149 1.225157746 0.981179462 1.171652872 1.116272268 1.369182478 1.045043785 0.781842173 1.166651555 1 11.94239403 -7.47274242 24.69625074 1.004411736 1.106767215 0 0.154492121 559.0464821 275377.7383 0.02431003 0.027751802 3.37E-08 7.47274242 0.102355479 VQNHLPASGPTQPPVVSSTNEGS(ph)PSPPEPTGK ddPTM_HeLa_Curcumin_4h_R1 1 VQNHLPASGPTQPPVVSSTNEGSPSPPEPTGK 32 0 O43294;H3BQC4;O43294-2 O43294 TGFB1I1 Transforming growth factor beta-1-induced transcript 1 protein 1 0 VQNHLPASGPTQPPVVS(0.006)S(0.006)T(0.042)NEGS(0.842)PS(0.104)PPEPT(0.001)GK 96.837 4.78E-09 36458000 4241.2 4256.9 4199.7 4104.7 4417.6 5616.5 4932.8 2597.1 4916.9 3769.8 TRUE FALSE FALSE 3905.504545 4624.847468 4355.344576 4087.715839 4364.923005 4451.574589 5071.201092 3388.943834 4377.528371 3900.800269 1.001205977 1.18561504 1.116525912 1.047917237 1.118981415 1.141195212 1.300041207 0.868781686 1.122212897 1 11.92955442 -7.287261009 22.50267673 1.000569457 1.117762839 0.040787188 0.109567011 220.1315427 191836.4607 0.015918449 0.018209227 5.16E-08 7.287261009 0.117193383 VQPSGGPAADQDVLGEES(ph)PLGKPAMLHLPSEQGAPETLQR ddPTM_HeLa_Curcumin_4h_R1 1 VQPSGGPAADQDVLGEESPLGKPAMLHLPSEQGAPETLQR 40 1 C9J2V2 C9J2V2 IKBKG 1 0 VQPSGGPAADQDVLGEES(0.932)PLGKPAMLHLPS(0.059)EQGAPET(0.008)LQR 51.583 0.0010447 12993000 734.1 509.89 734.91 667.5 739.33 1033.5 789.29 650.5 767.68 655.14 TRUE FALSE FALSE 675.9952104 553.9626196 762.1464111 664.7380619 730.5139726 819.1404501 811.4353531 848.8344555 683.4674246 677.9060662 0.997181238 0.817167226 1.124265513 0.980575473 1.077603534 1.208339165 1.196973141 1.252141702 1.00820373 1 9.404941571 -5.389821678 1.606060593 0.99092139 1.232478407 0.679458187 0.070994266 0.165894955 0.818174616 0.010034293 0.031857447 4.08E-06 5.389821678 0.241557017 VQQLVPK ddPTM_HeLa_Curcumin_4h_R1 2 VQQLVPK 7 0 O43707;O43707-2;F5GXS2;O43707-3;H7C144 O43707 ACTN4 Alpha-actinin-4 0 0 ; ; 111.28 0.013057 17446600 20324.2 11708.9 18718.2 15601.2 17444.6 20595.9 17882.4 17622.1 14605.2 13582.6 FALSE FALSE TRUE 18715.51812 12720.96514 19411.91296 15536.64637 17236.58454 16324.07818 18384.13202 22994.99717 13003.0461 14054.59434 1.331629905 0.905110801 1.381179171 1.105449648 1.226402137 1.161476296 1.308051415 1.636119593 0.925181175 1 13.77875419 -1.000000445 0.027199054 2.42E-07 2.987691252 0.381210001 0.169736906 1566.025258 3.305128603 121.5040326 269.0609227 0.099999897 1.000000445 2.98769101 VQQSSESSTSS(ph)PSQHEATPGAR ddPTM_HeLa_Curcumin_4h_R1 1 VQQSSESSTSSPSQHEATPGAR 22 0 O75152;E9PBY7;E9PQ61;A0A1B0GTU1;A0A494C0C4 O75152 ZC3H11A Zinc finger CCCH domain-containing protein 11A 1 0 VQQSSES(0.001)S(0.001)T(0.005)S(0.381)S(0.588)PS(0.023)QHEATPGAR 99.722 0.00014709 0 306.35 208.87 319.27 190.05 314.57 938.44 308.7 186.97 452.81 196.92 TRUE FALSE FALSE 282.1020742 226.9237921 331.1024271 189.2636235 310.8189582 743.7969656 317.3612912 243.9762923 403.1378759 203.7629553 1.384462027 1.113665591 1.624939266 0.928842159 1.525394828 3.650305152 1.557502396 1.197353522 1.978465002 1 7.670747979 -5.511062067 24.94921906 1.202309943 2.162390451 0.20703109 0.666997703 471.2203763 994913.0508 0.08600898 0.18286475 3.08E-06 5.511062067 0.960080508 VQQTVQDLFGR ddPTM_HeLa_Curcumin_4h_R1 1 VQQTVQDLFGR 11 0 P38646 P38646 HSPA9 "Stress-70 protein, mitochondrial" 0 0 108.43 0.0051098 988510 411.27 554.88 192.3 595.27 405.82 334.15 445.59 235.66 329.77 337.68 FALSE FALSE TRUE 378.7175455 602.8413547 199.4268072 592.8069305 400.9808615 264.8435234 458.0920562 307.5116492 293.595056 349.4143549 1.083863729 1.725290751 0.570745891 1.696572915 1.147579817 0.757964061 1.311028153 0.88007732 0.840248982 1 8.448795069 -3.090454547 13.87177639 1.093539093 1.111020129 0 0.362969717 0 0 0.041488361 0 0.00081198 3.090454547 0.017481036 VQS(ph)PEPPAPER ddPTM_HeLa_Curcumin_4h_R1 1 VQSPEPPAPER 11 0 A0A0G2JMS7;A0A0G2JNZ2;A0A669KB89;Q14160-2;Q14160;A0A0G2JPP5;Q14160-3;H0YCG0 A0A0G2JMS7 SCRIB Protein scribble homolog 1 0 VQS(1)PEPPAPER 122.46 0.003879 17989000 1715.7 1534.6 1746.2 1561.9 1206.8 1291.5 1004.1 839.51 1917.9 1465.4 TRUE FALSE FALSE 1579.900535 1667.243986 1810.915708 1555.437272 1192.409698 1023.628342 1032.272344 1095.472734 1707.511168 1516.322541 1.04192907 1.099531228 1.194281335 1.025795785 0.786382624 0.675072957 0.680773593 0.722453637 1.126087044 1 10.56636095 -5.677017721 3.372562589 1.042643563 0.695950592 0.896110006 0.060658649 0.06202963 1.399619229 0.009544136 0.019897468 2.10E-06 5.677017721 -0.346692971 VQS(ph)PKPITGGLGAFTK ddPTM_HeLa_Curcumin_4h_R1 1 VQSPKPITGGLGAFTK 16 1 Q9ULM3 Q9ULM3 YEATS2 YEATS domain-containing protein 2 1 0 VQS(0.999)PKPIT(0.001)GGLGAFTK 67.668 0.01238 22789000 3124.3 2324.3 2197.7 2626 2940.4 3544.8 3094.9 2048 2924.9 2789.5 TRUE FALSE FALSE 2877.008358 2525.202135 2279.148695 2615.134308 2905.33765 2809.568522 3181.734565 2672.425772 2604.045788 2886.434917 0.996734186 0.874851576 0.78960682 0.906008409 1.006548817 0.97336978 1.102306013 0.92585693 0.902166812 1 11.49507298 VQS(ph)SPNLLAAGR ddPTM_HeLa_Curcumin_4h_R1 2 VQSSPNLLAAGR 12 0 O94875-12;O94875-11;O94875-9;C9J372;C9IZT7;C9JWC3;C9JN77;C9J4Z9;C9JI79;C9JDX2;C9JBB0;C9JZ60;C9JEA9;C9JG84;C9J9D3 O94875-12 SORBS2 Sorbin and SH3 domain-containing protein 2 1 0 VQS(0.5)S(0.5)PNLLAAGR;VQS(0.5)S(0.5)PNLLAAGR ; 141.59 0.0011073 25405000 2128.74 1561.34 1765.71 1634.72 1817.79 3708.9 2816 1598.45 2311.98 2086.28 TRUE FALSE FALSE 1960.247983 1696.295272 1831.148766 1627.955962 1796.114041 2939.632332 2895.009381 2085.810047 2058.361578 2158.778075 0.908035896 0.785766398 0.848233909 0.75410992 0.832004949 1.361711223 1.341040756 0.966199384 0.953484567 1 11.07599922 -5.26658828 24.97011247 0.911405803 1.234789488 0.610059676 0.126488138 234.2091954 1135823.194 0.019270322 0.044332674 5.41E-06 5.26658828 0.323383685 VQSGMGLILQGY(ph)ES(ph)GSEEEGEIHEK ddPTM_HeLa_Curcumin_4h_R1 1 VQSGMGLILQGYESGSEEEGEIHEK 25 0 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 2 0 VQS(0.001)GMGLILQGY(0.874)ES(0.562)GS(0.562)EEEGEIHEK 69.649 0.00035337 8807100 1595.5 1320.3 1481 1698.3 1460.4 1714.7 1372.8 1541.8 1900.5 1668.1 TRUE FALSE FALSE 1469.214491 1434.420849 1535.887163 1691.272885 1442.985684 1359.051891 1411.317073 2011.887722 1692.019905 1726.066351 0.85119236 0.831034594 0.889819306 0.979842336 0.835996648 0.787369437 0.817649375 1.165591185 0.980275123 1 10.75327221 -9.374739278 1.100148014 0.999966174 0.884693069 0.111199535 0.104232837 0.77311181 1.674827836 0.068125724 0.017598881 4.22E-10 9.374739278 -0.115273105 VQSGMGLILQGYES(ph)GS(ph)EEEGEIHEK ddPTM_HeLa_Curcumin_4h_R1 1 VQSGMGLILQGYESGSEEEGEIHEK 25 0 Q13523 Q13523 PRPF4B Serine/threonine-protein kinase PRP4 homolog 2 0 VQSGMGLILQGY(0.439)ES(0.781)GS(0.781)EEEGEIHEK 83.317 0.00010741 48503000 3556.9 2600.1 2847.5 2289.4 2773 3579.5 2598.3 2515.3 3103.6 2915.8 TRUE FALSE FALSE 3275.367612 2824.841058 2953.030855 2279.927069 2739.933786 2837.071351 2671.201305 3282.203391 2763.142845 3017.123833 1.085592701 0.936269512 0.978756928 0.755662411 0.90812772 0.940323138 0.885346924 1.087858362 0.915820164 1 11.5589582 -7.144674398 5.11182685 1.040263747 0.91938724 0.071547361 0.089286534 0.201014001 7.725750742 0.013490233 0.016598048 7.17E-08 7.144674398 -0.120876507 VQSGNINAAK ddPTM_HeLa_Curcumin_4h_R1 2 VQSGNINAAK 10 0 P49368;P49368-2;Q5SZX9;E9PRC8;Q5SZX6;E9PM09;Q5SZW8 P49368 CCT3 T-complex protein 1 subunit gamma 0 0 ; ; 174.86 5.94E-13 6685300 2198.92 1691.99 1922.64 1779.58 1849.14 2613.8 1778.65 1687.4 1970.82 1709.21 FALSE FALSE TRUE 2024.873162 1838.238076 1993.89473 1772.216569 1827.090213 2071.668416 1828.554132 2201.880492 1754.625977 1768.60492 1.144898523 1.039371798 1.127382779 1.002042089 1.033068602 1.171357375 1.033896328 1.244981548 0.992096062 1 10.78839609 -9.51523278 1.237664602 0.999415703 1.099185923 0.249137464 0.071556894 0.56901464 1.545549421 0.048472972 0.01138687 3.05E-10 9.51523278 0.09977022 VQSLEGEKLS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 VQSLEGEKLSPK 12 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 VQSLEGEKLS(1)PK 147.56 0.0068204 517240000 2821.3 2113.3 2564.6 2599.7 2404 3019.9 1918.8 2125.4 2684.8 2320.5 TRUE FALSE FALSE 2597.991128 2295.964235 2659.646332 2588.94313 2375.33387 2393.538699 1972.636364 2773.424676 2390.284157 2401.137202 1.081983622 0.956198685 1.107661124 1.078215409 0.989253704 0.996835456 0.821542543 1.155046314 0.99548004 1 11.22950213 -5.614392944 6.796467199 1.040905126 0.977232403 0.055148909 0.086429387 0.361625514 22.61024266 0.011593228 0.023311364 2.43E-06 5.614392944 -0.063672723 VQSLEGEKLS(ph)PKS(ph)DIS(ph)PLTPR ddPTM_HeLa_Curcumin_4h_R1 2 VQSLEGEKLSPKSDISPLTPR 21 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 3 0 VQSLEGEKLS(0.991)PKS(0.991)DIS(0.966)PLT(0.052)PR;VQSLEGEKLS(0.996)PKS(0.999)DIS(0.991)PLT(0.014)PR ; 72.793 0.0020898 47934000 5112.2 4622 4447.9 5366.1 4992 4994.7 3872.2 4082.7 5874.2 5545.8 TRUE FALSE FALSE 4707.563976 5021.505085 4612.743087 5343.8965 4932.47366 3958.742918 3980.843511 5327.496436 5229.814957 5738.516137 0.820345166 0.875052882 0.803821576 0.931233157 0.85953817 0.689854803 0.693706076 0.928375264 0.911353185 1 12.48646202 -13.52287875 0.188081616 1.816541974 0.779569196 0.263625069 0.082662156 37.28039209 0.438464795 11.12801329 0.09625103 3.00E-14 13.52287875 -1.036972778 VQSLEGEKLSPKS(ph)DIS(ph)PLTPR ddPTM_HeLa_Curcumin_4h_R1 1 VQSLEGEKLSPKSDISPLTPR 21 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 VQS(0.001)LEGEKLS(0.099)PKS(0.95)DIS(0.904)PLT(0.046)PR 69.081 0.0025222 118040000 4716 3407.6 3953.6 4555.4 4117.9 4126.5 3443.1 3132.1 5101.8 4076.1 TRUE FALSE FALSE 4342.723624 3702.13776 4100.123894 4536.550962 4068.796732 3270.617385 3539.704119 4087.062872 4542.145304 4217.744172 1.029631824 0.877753038 0.972112989 1.075587038 0.964685521 0.775442334 0.839241067 0.969016305 1.076913421 1 12.04225588 -5.463263274 7.451150743 1.003996926 0.860074409 0.466358824 0.068953873 0.175603876 19.39896135 0.009218174 0.020600317 3.44E-06 5.463263274 -0.143922517 VQT(ph)PEVDVK ddPTM_HeLa_Curcumin_4h_R1 3 VQTPEVDVK 9 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VQT(1)PEVDVK;VQT(1)PEVDVK;VQT(1)PEVDVK ;; 138.42 0.0075238 206093000 20342.6 14195.6 17520.5 19008 17793.5 27776.9 24665.5 7137.7 17100.8 11607.5 TRUE FALSE FALSE 18732.46174 15422.60441 18169.82514 18929.34993 17581.32413 22015.65783 25357.54755 9313.951872 15224.88502 12010.85976 1.559627047 1.28405499 1.512783057 1.576019561 1.463785648 1.832979343 2.111218352 0.775460879 1.267593272 1 13.55205181 -9.944575065 0.366322441 0.635701921 1.58553491 0.14129179 0.338311448 4.190320943 0.500881951 1.676580296 0.113592479 1.14E-10 9.944575065 0.949832988 VQT(ph)TPPPAVQGQK ddPTM_HeLa_Curcumin_4h_R1 3 VQTTPPPAVQGQK 13 0 Q2M2I8-2;Q2M2I8;E9PG46 Q2M2I8-2 AAK1 AP2-associated protein kinase 1 1 0 VQT(0.905)T(0.095)PPPAVQGQK;VQT(0.907)T(0.093)PPPAVQGQK;VQT(0.97)T(0.03)PPPAVQGQK ;; 162.49 0.00061186 106308000 16263 14159.5 14436.5 16240.3 15565.9 17591.9 12817.8 11326.8 16873.4 15217.3 TRUE FALSE FALSE 14975.76639 15383.38409 14971.52939 16173.10194 15380.28681 13943.14164 13177.43297 14780.28918 15022.43024 15746.10004 0.951077813 0.976964712 0.95080873 1.027117947 0.97676801 0.885498098 0.836869633 0.938663487 0.954041331 1 13.94270693 -5.257947633 6.762868257 0.978313565 0.881626987 0.622066931 0.031941612 0.063546126 17.84804024 0.004495226 0.010894843 5.52E-06 5.257947633 -0.096686578 VQTHLENPTK(ac)YHIQQAQR ddPTM_HeLa_Curcumin_4h_R1 2 VQTHLENPTKYHIQQAQR 18 1 C9J845;C9JBI8;O75030-12;O75030-4;O75030-3;O75030-8;O75030-7;O75030-6;O75030-2;O75030-5;O75030 C9J845 MITF Microphthalmia-associated transcription factor 0 1 ; VQTHLENPTK(1)YHIQQAQR;VQTHLENPTK(1)YHIQQAQR 101.9 0.0006599 9209800 1968.17 1501.28 1848.44 1837.62 2121.1 4823.4 4652.3 3043.5 2203.2 2097.56 FALSE TRUE FALSE 1812.387268 1631.043954 1916.944812 1830.016415 2095.807268 3822.972469 4782.831017 3971.449139 1961.514472 2170.450054 0.835028323 0.751477303 0.883201532 0.843150669 0.965609535 1.76137316 2.203612568 1.829781401 0.903736287 1 11.08377851 -5.200778713 3.219483532 0.896913372 2.01325085 0.953521143 0.107010203 0.037410708 0.76722717 0.016142505 0.044784159 6.30E-06 5.200778713 1.116337478 VQTT(ph)PSKPGGDR ddPTM_HeLa_Curcumin_4h_R1 1 VQTTPSKPGGDR 12 1 Q12834 Q12834 CDC20 Cell division cycle protein 20 homolog 1 0 VQT(0.032)T(0.484)PS(0.484)KPGGDR 160.56 0.0019926 183530000 9143.3 7745.6 7752.5 8235.8 8160 10047 8060.2 3925 10283 7859.6 TRUE FALSE FALSE 8419.598157 8415.09515 8039.81447 8201.722442 8062.697329 7963.138947 8286.347519 5121.714432 9154.980627 8132.720515 1.035274499 1.034720809 0.988576265 1.008484483 0.991389943 0.979148236 1.018889989 0.629766438 1.12569719 1 12.98952232 -4.260783353 24.99391292 1.011681502 0.62976632 0.893430135 0.040360465 6.527991126 248654.7782 0.002942812 0.023471801 5.49E-05 4.260783353 -0.381915181 VQVAALQAS(ph)PPLDQDDR ddPTM_HeLa_Curcumin_4h_R1 3 VQVAALQASPPLDQDDR 17 0 Q9UDY2-7;A0A2R8YDH4;A0A1B0GTW1;A0A3B3ITE1;Q9UDY2-3;Q9UDY2;Q9UDY2-6;A0A3B3IRI3;Q9UDY2-2;Q9UDY2-4;A0A3B3IU51;A0A3B3ISZ5;Q9UDY2-5;A0A3B3IRV6;A0A3B3ISF1;A0A3B3IU26;B1AN86;U3KQJ2 Q9UDY2-7 TJP2 Tight junction protein ZO-2 1 0 VQVAALQAS(1)PPLDQDDR;VQVAALQAS(1)PPLDQDDR;VQVAALQAS(1)PPLDQDDR ;; 176.85 1.13E-05 36870700 7333.5 6324.2 7079.9 6572 7382.9 7932.6 5739.3 6624.5 5888.9 5753.9 TRUE FALSE FALSE 6753.045737 6870.835668 7342.287322 6544.806805 7294.863739 6287.289341 5900.329311 8644.279555 5242.902403 5953.847597 1.134232213 1.154016047 1.233200414 1.099256691 1.225235215 1.056004414 0.991011143 1.451881227 0.88059063 1 12.53960658 -8.853110059 0.551597085 0.986051389 1.165381166 0.328377608 0.123802539 1.210148067 0.645801113 0.107409354 0.028828613 1.40E-09 8.853110059 0.179329777 VQVEYK(ac)GETK ddPTM_HeLa_Curcumin_4h_R1 2 VQVEYKGETK 10 1 P11142;E9PKE3;P11142-2;E9PN89;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PPY6;E9PN25;P54652 P11142;P54652 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 1 ; VQVEYK(1)GETK;VQVEYK(1)GETK 160.36 6.02E-09 12867700 4414.1 4711.1 4094.3 3443.5 6575.9 8475.3 6539.9 6097.5 8211.2 4277.3 FALSE TRUE FALSE 4064.719327 5118.306492 4246.03836 3429.251709 6497.486687 6717.427244 6723.391993 7956.599681 7310.451903 4425.935857 0.918386407 1.156434855 0.959353795 0.774808271 1.468048091 1.517741662 1.519089343 1.797721417 1.651730197 1 12.11176683 -5.650211318 5.298023363 0.965586698 1.584477128 0.468489236 0.245895262 0.052414442 2.241705363 0.016671234 0.033746858 2.24E-06 5.650211318 0.61889043 VQVEYKGETK ddPTM_HeLa_Curcumin_4h_R1 1 VQVEYKGETK 10 1 P11142;E9PKE3;P11142-2;E9PN89;E9PQQ4;E9PQK7;E9PK54;E9PLF4;E9PPY6;E9PN25;P54652 P11142;P54652 HSPA8;HSPA2 Heat shock cognate 71 kDa protein;Heat shock-related 70 kDa protein 2 0 0 80.737 0.018859 13497000 5788.6 3828.7 4303.9 4366.7 3836.7 5545.9 4032.6 4493.5 5059.4 4626.7 FALSE FALSE TRUE 5330.426202 4159.635768 4463.40632 4348.631752 3790.949858 4395.617825 4145.743903 5863.547464 4504.396478 4787.477481 1.113410188 0.868857511 0.932308578 0.908334665 0.791847037 0.918149034 0.865955802 1.224767634 0.940870531 1 12.22504999 -7.259427165 24.99599261 1.053554811 0.921048303 0.081784578 0.115820049 191.8481363 2383168.594 0.018280707 0.021800525 5.50E-08 7.259427165 -0.132506508 VRDVFEAK ddPTM_HeLa_Curcumin_4h_R1 2 VRDVFEAK 8 1 P12268;H0Y4R1;E7ETK5 P12268 IMPDH2 Inosine-5-monophosphate dehydrogenase 2 0 0 ; ; 86.136 0.015072 4969400 2875.3 1820.49 2352.34 2194.74 2299.6 3059.3 2430.1 2205.86 2943.5 2592 FALSE FALSE TRUE 2647.716971 1977.845044 2439.51979 2185.658747 2272.178772 2424.766695 2498.282066 2878.416559 2620.605414 2682.071807 0.987190934 0.737431801 0.909565427 0.814914329 0.847172982 0.904064794 0.931474713 1.073206374 0.977082495 1 11.38913215 -7.476721778 24.99494418 0.994349041 0.885189491 0.236897742 0.081847046 384.6396644 208291.6144 0.01374352 0.01565392 3.34E-08 7.476721778 -0.109159551 VREEEIEVDSR ddPTM_HeLa_Curcumin_4h_R1 3 VREEEIEVDSR 11 1 A0A0A0MRM9;Q14978;Q14978-3;Q14978-2 A0A0A0MRM9 NOLC1 Nucleolar and coiled-body phosphoprotein 1 0 0 ;; ;; 145.14 0.00086064 99963000 18864.9 15491.1 16940.4 16465.9 16287.3 20831.2 16262 15823.2 19159.6 16283.3 FALSE FALSE TRUE 17371.72326 16830.08166 17568.22613 16397.76847 16093.08459 16510.5743 16718.26795 20647.62084 17057.83981 16849.14346 1.031015214 0.998868678 1.042677698 0.973210805 0.955127756 0.979905853 0.992232513 1.225440384 1.01238617 1 14.04038763 -4.259328868 24.99378241 1.005568908 1.22544046 0.87479083 0.02564131 53.86926822 637902.1764 0.003995055 0.035301121 5.50E-05 4.259328868 0.219871552 VREEFK(ac)ELK ddPTM_HeLa_Curcumin_4h_R1 1 VREEFKELK 9 2 P02545;P02545-3;P02545-6;P02545-2;Q3BDU5 P02545;P02545-2 LMNA Prelamin-A/C;Lamin-A/C 0 1 VREEFK(1)ELK 126.39 0.0001943 4154100 2939.5 2651 2540 2424.3 2786.7 3483.4 2711.3 2350.1 3477.8 2932.8 FALSE TRUE FALSE 2706.835473 2880.140627 2634.134634 2414.268889 2753.470423 2760.903574 2787.371781 3066.634671 3096.294041 3034.714582 0.891957184 0.949064747 0.868000783 0.795550561 0.907324346 0.90977372 0.918495531 1.010518317 1.020291681 1 11.56734512 -9.246043971 0.799500376 1.005225134 0.902307851 0.376924266 0.052501348 0.709915741 0.74959164 0.046758756 0.010568962 5.67E-10 9.246043971 -0.102917282 VREEYPDR ddPTM_HeLa_Curcumin_4h_R1 2 VREEYPDR 8 1 A0A0B4J269;Q13509;Q13509-2;G3V2A3 A0A0B4J269 TUBB3 Tubulin beta-3 chain 0 0 ; ; 134.05 0.0037918 16038100 5979.9 4040.5 4751.1 4823.4 4960 6142.4 4066.8 4460.1 5319.3 4908.2 FALSE FALSE TRUE 5506.584605 4389.742816 4927.179945 4803.442049 4900.855239 4868.397001 4180.903463 5819.963958 4735.786098 5078.759585 1.084238093 0.864333651 0.970154201 0.945790398 0.964970906 0.958579929 0.823213502 1.145942008 0.932469045 1 12.31026047 -7.278187406 24.98242882 1.039779099 0.949294716 0.026562646 0.088112884 876.6082505 1307601.599 0.013078232 0.014974955 5.27E-08 7.278187406 -0.090484383 VRELELELDR ddPTM_HeLa_Curcumin_4h_R1 2 VRELELELDR 10 1 O94992 O94992 HEXIM1 Protein HEXIM1 0 0 ; ; 150.09 0.00067874 8583600 7539 7233.6 7849.1 7265.3 6790.9 9436.3 7595.4 6892.6 9013.9 8979.6 FALSE FALSE TRUE 6942.280195 7858.840152 8139.994551 7235.238114 6709.922953 7479.105011 7808.506482 8994.12201 8025.097722 9291.640432 0.747153341 0.845796844 0.876055699 0.778682534 0.722146213 0.804928373 0.840379752 0.96797999 0.863690086 1 13.18171761 -9.443340689 1.12581822 1.001991991 0.813740045 0.156542427 0.077469911 0.336563445 0.750008766 0.050454207 0.012048004 3.60E-10 9.443340689 -0.188251946 VREYELR ddPTM_HeLa_Curcumin_4h_R1 2 VREYELR 7 1 P62913;Q5VVC8;P62913-2 P62913 RPL11 60S ribosomal protein L11 0 0 ; ; 87.323 0.018021 9168600 6371.8 4914.9 5352.2 5514.3 5608 7986 5329.3 5329.8 5886.8 4995 FALSE FALSE TRUE 5867.465307 5339.722056 5550.55724 5491.483288 5541.128263 6329.613579 5478.825815 6954.831485 5241.032768 5168.575878 1.135218955 1.033112831 1.073904567 1.062475122 1.072080278 1.224633967 1.060026194 1.345599184 1.014018734 1 12.33555111 -1 0.68649732 1.063826414 29.47862037 0.624184705 0.062331725 139.9007133 0.730343285 0.011065823 6096.689333 0.1 1 28.41479395 VRGEVAPDAK ddPTM_HeLa_Curcumin_4h_R1 4 VRGEVAPDAK 10 1 P09382;F8WEI7 P09382 LGALS1 Galectin-1 0 0 ;;; ;;; 103.21 0.0037361 163382000 38837.8 31040.4 33116.6 32093.6 32853.2 44038 33376.7 32149.6 37507.4 32544.3 FALSE FALSE TRUE 35763.74715 33723.39386 34343.93033 31960.80519 32461.44705 34904.02239 34313.16037 41951.86504 33392.93206 33675.212 1.062019955 1.001430781 1.01985788 0.949089947 0.963956724 1.036490056 1.018944153 1.245778795 0.991617575 1 15.03939941 -4.261330096 8.221527549 1.017553883 1.247400679 0.820114305 0.033379504 0.033507009 30.54000014 0.005345864 0.042324721 5.48E-05 4.261330096 0.229846796 VRGGAPDPSPGATATPGAPAQPS(ph)SPDAR ddPTM_HeLa_Curcumin_4h_R1 3 VRGGAPDPSPGATATPGAPAQPSSPDAR 28 1 O95365 O95365 ZBTB7A Zinc finger and BTB domain-containing protein 7A 1 0 VRGGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR;VRGGAPDPSPGATATPGAPAQPS(0.601)S(0.399)PDAR;VRGGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR ;; 153.96 1.99E-11 126841000 7154.7 4136.7 5734.8 5845 5072.9 6125 4616.3 4415.13 7266.8 5162.8 TRUE FALSE FALSE 6588.397945 4494.257915 5947.336733 5820.814939 5012.408981 4854.605957 4745.820954 5761.282812 6469.650221 5342.206916 1.2332727 0.841273651 1.113273377 1.089589945 0.938265601 0.90872668 0.888363373 1.078446212 1.211044485 1 12.38322014 -5.763193805 24.2732426 1.089288897 0.945606809 0.23211627 0.113116017 35.8946494 496634.5621 0.017973627 0.033856431 1.73E-06 5.763193805 -0.143682088 VRPAS(ph)TGGLSLLPPPPGGK ddPTM_HeLa_Curcumin_4h_R1 1 VRPASTGGLSLLPPPPGGK 19 1 D6RB24;Q9NVZ3-4;Q9NVZ3;Q9NVZ3-2 D6RB24 NECAP2 Adaptin ear-binding coat-associated protein 2 1 0 VRPAS(0.452)T(0.452)GGLS(0.096)LLPPPPGGK 86.357 0.0012726 88362000 3181.9 2409.6 2361.5 2982.7 2714.1 4554.9 4459.8 2461.5 3553.8 2440.6 TRUE FALSE FALSE 2930.049257 2617.875087 2449.019267 2970.358378 2681.73613 3610.162396 4584.929985 3212.000019 3163.957031 2525.410668 1.160226847 1.036613617 0.9697509 1.176188259 1.061901006 1.429534785 1.815518578 1.271872357 1.252848525 1 11.30230229 -5.172565559 3.876685677 1.072603951 1.558675777 0.619323315 0.148256743 0.089839215 2.496400782 0.018231195 0.049547702 6.72E-06 5.172565559 0.486071826 VRPAST(ph)GGLSLLPPPPGGK ddPTM_HeLa_Curcumin_4h_R1 1 VRPASTGGLSLLPPPPGGK 19 1 D6RB24;Q9NVZ3-4;Q9NVZ3;Q9NVZ3-2 D6RB24 NECAP2 Adaptin ear-binding coat-associated protein 2 1 0 VRPAS(0.289)T(0.602)GGLS(0.109)LLPPPPGGK 108.56 0.0052582 28911000 1490.9 1015.9 1288 1113.1 1153.1 2863.4 1977.5 1018.7 1434 1172.2 TRUE FALSE FALSE 1372.893692 1103.709869 1335.734413 1108.494287 1139.350036 2269.498563 2032.983328 1329.29694 1276.693788 1212.933863 1.131878443 0.909950578 1.101242577 0.913895078 0.939334015 1.871081872 1.676087535 1.095935221 1.052566695 1 10.24428517 -5.276521753 24.90005804 1.036387817 1.560540154 0.614568136 0.195183486 353.8197181 584134.0178 0.026821225 0.060197783 5.29E-06 5.276521753 0.524152336 VRQS(ph)PLATR ddPTM_HeLa_Curcumin_4h_R1 1 VRQSPLATR 9 1 K7EK59;O75381-2;O75381 K7EK59 PEX14 Peroxisomal membrane protein PEX14 1 0 VRQS(1)PLATR 80.871 0.013696 5907500 1033.8 733.97 855.25 852.84 952.79 867.53 797.94 271.55 859.55 904.77 TRUE FALSE FALSE 951.9736391 797.4110963 886.9463174 849.3111741 941.4286015 687.5944989 820.3280489 354.3443449 765.2595155 936.2106902 1.016836968 0.851743208 0.947378968 0.90717953 1.005573437 0.734444187 0.876221621 0.378487822 0.817400958 1 9.870689428 -4.047307558 0.892437381 0.985831099 8.66E-33 0.671899736 0.103198797 0.971596474 0.446865199 0.013051807 1.018326517 8.97E-05 4.047307558 -0.985831099 VRS(ph)LETENR ddPTM_HeLa_Curcumin_4h_R1 2 VRSLETENR 9 1 P05783;F8VZY9 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 VRS(0.998)LET(0.002)ENR;VRS(0.961)LET(0.039)ENR ; 81.676 0.013237 24541000 1507.25 1339.54 1744.94 1712.56 1575.76 2060.56 1625.32 1207.13 1672.21 1756.8 TRUE FALSE FALSE 1387.949572 1455.323869 1809.609011 1705.47388 1556.970091 1633.176629 1670.922105 1575.17838 1488.772747 1817.848669 0.763512164 0.800574819 0.995467358 0.938182539 0.856490487 0.898411763 0.91917558 0.866506881 0.818975073 1 10.82801639 -9.673863431 1.553005127 0.999573894 0.864856929 0 0.084539231 0.394771452 1.723068444 0.05370481 0.012168542 2.12E-10 9.673863431 -0.134716965 VRSS(ph)PSGNTQS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 VRSSPSGNTQSSPK 14 1 O00512 O00512 BCL9 B-cell CLL/lymphoma 9 protein 2 0 VRS(0.187)S(0.813)PSGNT(0.003)QS(0.751)S(0.246)PK 154.47 0.0016478 2943500 2682.5 2042.8 2367.5 2260.1 2334 2500.2 1807 1520.7 2832.2 2306.7 TRUE FALSE FALSE 2470.177294 2219.370529 2455.241633 2250.748305 2306.168574 1981.630337 1857.699557 1984.35443 2521.514746 2386.857653 1.034907671 0.929829446 1.028650213 0.942975507 0.966194432 0.830225604 0.778303454 0.831366892 1.056416055 1 11.22089681 -5.36027731 1.354089214 1.00904967 0.793064179 0.82117605 0.0389447 0.119910795 0.409677134 0.005448436 0.020025749 4.36E-06 5.36027731 -0.21598549 KLCQPQSTGSLLGDPAAS(ph)SPPGER ddPTM_HeLa_Curcumin_4h_R1 2 KLCQPQSTGSLLGDPAASSPPGER 24 1 U3KQ90;P55199 U3KQ90 ELL RNA polymerase II elongation factor ELL 1 0 KLCQPQSTGSLLGDPAAS(0.751)S(0.249)PPGER;KLCQPQSTGSLLGDPAAS(0.738)S(0.262)PPGER ; 176.68 2.79E-11 64305000 4628 3693.6 3430.4 4014.4 3475.7 4962.2 3107.2 1493.35 4806.8 3900.9 TRUE FALSE FALSE 4261.688917 4012.858326 3557.533642 3997.789476 3434.254548 3932.983784 3194.379669 1948.66554 4279.506066 4036.455985 1.055799675 0.994153867 0.881350783 0.990420679 0.850809364 0.974365582 0.791382262 0.482766454 1.060213733 1 11.97887344 -3.97208362 0.874317112 1.008249489 5.19E-30 0.845773027 0.064590002 0.931457262 0.375782925 0.010418456 1.011012841 0.000106639 3.97208362 -1.008249489 down VRTASIWGT(ph)NTPNLIS(ph)S(ph)S(ph)S(ph)WNK ddPTM_HeLa_Curcumin_4h_R1 1 VRTASIWGTNTPNLISSSSWNK 22 1 F5H670;Q14587-7;Q14587-4 F5H670 ZNF268 Zinc finger protein 268 5 0 VRT(0.026)AS(0.022)IWGT(0.9)NT(0.288)PNLIS(0.941)S(0.941)S(0.941)S(0.941)WNK 45.88 0.0085551 0 987.32 984.6 1019.7 1100.5 1080.8 1742 1105.3 1042.8 1190.4 993.24 TRUE FALSE FALSE 909.1725802 1069.704437 1057.490979 1095.946423 1067.912166 1380.689564 1136.311743 1360.74492 1059.816098 1027.755016 0.88461994 1.040816556 1.028932929 1.066349865 1.039072687 1.343403381 1.105625101 1.323997352 1.031195257 1 10.0052807 -5.654373694 0.802358764 0.949893862 1.270448036 0.610612595 0.084211821 0.320159903 0.363133457 0.01453126 0.06010496 2.22E-06 5.654373694 0.320554174 VRTELADK(ac)VTK ddPTM_HeLa_Curcumin_4h_R1 1 VRTELADKVTK 11 2 P35579 P35579 MYH9 Myosin-9 0 1 VRTELADK(1)VTK 97.779 0.002861 4469900 2276.7 2715.9 2738.9 2716.7 3325.5 4880.6 3152.9 3512.8 5746.3 3212.9 FALSE TRUE FALSE 2096.496793 2950.650294 2840.406043 2705.459015 3285.845584 3868.308544 3241.361888 4583.836549 5115.945267 3324.548036 0.63061107 0.887534264 0.854373591 0.813782501 0.988358583 1.163559227 0.974978209 1.378784875 1.538839328 1 11.69894251 -4.454146285 0.675214114 0.825675027 1.516409209 0.022577268 0.254178778 1.548686075 0.568045208 0.027124057 0.775876165 3.51E-05 4.454146285 0.690734182 VRVELSNGEK ddPTM_HeLa_Curcumin_4h_R1 1 VRVELSNGEK 10 1 P84103;P84103-2 P84103 SRSF3 Serine/arginine-rich splicing factor 3 0 0 87.667 0.012714 6561700 3073.9 2193.7 2365.5 2706.9 2531.9 3339.4 2282.6 2476.1 2892.9 2455.1 FALSE FALSE TRUE 2830.597571 2383.313653 2453.167511 2695.699565 2501.708746 2646.770797 2346.643613 3231.051491 2575.556108 2540.414542 1.114226645 0.938159349 0.96565638 1.06112586 0.984763984 1.041865709 0.923724681 1.271859942 1.013833004 1 11.31084822 -4.244739478 24.48201564 1.029892314 1.271860195 0.624207417 0.059356516 1516.297458 2222842.088 0.00929551 0.33333189 5.69E-05 4.244739478 0.24196788 VRVELSNGEK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 VRVELSNGEKR 11 2 P84103;P84103-2 P84103 SRSF3 Serine/arginine-rich splicing factor 3 0 1 ; VRVELSNGEK(1)R;VRVELSNGEK(1)R 122.18 0.00040807 8335000 3059.19 3578 2841.69 3314.6 4113.1 6572.5 4380.4 3970.3 5375.4 3387.8 FALSE TRUE FALSE 2817.051883 3887.266377 2947.005531 3300.885063 4064.053969 5209.289413 4503.302235 5180.826193 4785.732069 3505.525798 0.803603238 1.108896811 0.840674324 0.941623384 1.159327931 1.486022273 1.284629609 1.477902743 1.365196648 1 11.77541514 -5.55098287 2.750843395 0.917785548 1.402673216 0.485915234 0.170900138 0.082432926 1.258767698 0.015386134 0.035320581 2.81E-06 5.55098287 0.484887668 VRVELSTGMPR ddPTM_HeLa_Curcumin_4h_R1 1 VRVELSTGMPR 11 1 Q16629-4;Q16629;A0A0B4J1Z1;C9JAB2;Q16629-3;Q16629-2 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 0 0 100.09 0.0049804 4402000 1136.3 656.25 889.2 918.92 956.55 1611.5 1012.1 1064.9 1080 1043.1 FALSE FALSE TRUE 1046.360656 712.9733258 922.1545342 915.1177525 945.143766 1277.256735 1040.496802 1389.583108 961.526702 1079.347647 0.969438029 0.660559485 0.854362852 0.847843375 0.875662043 1.18335991 0.964005253 1.287428672 0.890840597 1 10.0759439 -5.261251632 24.99949541 0.93322949 1.12683868 0.456257911 0.124192749 15.91355864 2118789.558 0.018996744 0.045303124 5.48E-06 5.261251632 0.19360919 VRVS(ph)PQDANPLMANGTLTR ddPTM_HeLa_Curcumin_4h_R1 2 VRVSPQDANPLMANGTLTR 19 1 O60716;O60716-2;O60716-5;O60716-3;A0A669KB05;C9JZR2;O60716-8;O60716-7;O60716-4;O60716-6;A0A669KB62 O60716 CTNND1 Catenin delta-1 1 0 VRVS(1)PQDANPLMANGTLTR;VRVS(1)PQDANPLMANGTLTR ; 96.793 0.00056668 88938000 3555.7 2727.2 3147.7 2890.1 2798.7 3693.7 2193.34 1655.98 3560.3 2404.89 TRUE FALSE FALSE 3274.262593 2962.927016 3264.356531 2878.141532 2765.32733 2927.584983 2254.879217 2160.880679 3169.743997 2488.459748 1.315778805 1.190667045 1.311798004 1.156595574 1.111260623 1.176464673 0.906134495 0.868360712 1.273777484 1 11.28103734 -4.738369851 5.771055853 1.166205551 0.881371205 0.622342643 0.093319487 0.1157044 11.53281105 0.017462018 0.063970535 1.83E-05 4.738369851 -0.284834346 VRYDS(ph)SNQVK ddPTM_HeLa_Curcumin_4h_R1 1 VRYDSSNQVK 10 1 O95983-2;O95983;A0A087WZ12;A0A087WT34;A0A087X1H1;A0A0A0MTS6;K7EIE8 O95983-2 MBD3 Methyl-CpG-binding domain protein 3 1 0 VRYDS(0.762)S(0.238)NQVK 96.371 0.0065509 19656000 5906.4 5487.5 5209.4 5421.3 5619.1 4771.6 2684.1 1957.2 6371.9 5016.2 TRUE FALSE FALSE 5438.902208 5961.815048 5402.464947 5398.868097 5552.095902 3781.916373 2759.408622 2553.94127 5672.918512 5190.512577 1.047854548 1.148598517 1.040834574 1.040141608 1.069662354 0.728620982 0.531625457 0.492040282 1.092939941 1 12.3416613 -5.035160386 2.471209865 1.038907351 0.505361017 0.960297613 0.045739688 0.041648435 0.496936737 0.007031123 0.024471852 9.22E-06 5.035160386 -0.533546334 VS(ph)DFGGR ddPTM_HeLa_Curcumin_4h_R1 2 VSDFGGR 7 0 I3L4R8;P27694 I3L4R8 RPA1 "Replication protein A 70 kDa DNA-binding subunit;Replication protein A 70 kDa DNA-binding subunit, N-terminally processed" 1 0 VS(1)DFGGR;VS(1)DFGGR ; 115.7 0.014278 140418000 6860.2 5383.4 6250.1 5825 6446.8 8899.7 5711.2 3282.3 6379.2 5746.7 TRUE FALSE FALSE 6317.207931 5848.717108 6481.734204 5800.897693 6369.926121 7053.8019 5871.440901 4283.05816 5679.41772 5946.397397 1.062358855 0.983573199 1.090027082 0.975531453 1.071224423 1.186231163 0.987394637 0.720277821 0.955102281 1 12.53780017 -4.286993358 4.090934747 1.039862173 0.70022994 0.684033977 0.064809822 0.080110613 2.799663491 0.008145764 0.07587123 5.16E-05 4.286993358 -0.339632233 VS(ph)DSESEGPQK ddPTM_HeLa_Curcumin_4h_R1 1 VSDSESEGPQK 11 0 Q96ST2-3;Q96ST2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 0 VS(0.612)DS(0.387)ES(0.001)EGPQK 121.21 0.004042 22236000 2293.1 1957.4 2307.4 2125.5 3159.9 2288.1 2091.2 1790.1 1664.3 1687.5 TRUE FALSE FALSE 2111.598715 2126.588934 2392.914274 2116.705244 3122.220256 1813.522268 2149.873444 2335.893249 1481.730454 1746.140499 1.209294851 1.217879624 1.370401909 1.212219317 1.788069321 1.038588973 1.231214467 1.337746447 0.848574587 1 10.76995393 -8.189920845 0.579103891 1.008353497 1.327259217 0.378099997 0.189670639 0.678660051 0.510236597 0.093789783 0.050904223 6.46E-09 8.189920845 0.31890572 VS(ph)EFNVSSEGSGEK ddPTM_HeLa_Curcumin_4h_R1 1 VSEFNVSSEGSGEK 14 0 Q9BVJ6-3;Q9BVJ6 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 0 VS(0.451)EFNVS(0.318)S(0.23)EGSGEK 202.92 7.40E-31 0 2259.4 1594.8 1815.9 2215 1856 2938.2 2644.9 1118.4 1960.7 1558.7 TRUE FALSE FALSE 2080.566106 1732.647406 1883.198851 2205.834917 1833.868412 2328.7842 2719.108776 1459.395012 1745.616115 1612.864709 1.289981791 1.074267046 1.167611171 1.367650309 1.137025568 1.443880684 1.685887701 0.904846515 1.082307838 1 10.65540971 -13.1683173 0.173242045 3.31E-09 1.355288953 0.158500444 0.203309532 57.12816034 0.715999511 19.56155176 0.304966881 6.79E-14 13.1683173 1.35528895 NTS(ph)LPPLWSPEAER ddPTM_HeLa_Curcumin_4h_R1 1 NTSLPPLWSPEAER 14 0 P49790-3;P49790;P49790-2 P49790-3 NUP153 Nuclear pore complex protein Nup153 1 0 NT(0.098)S(0.901)LPPLWS(0.001)PEAER 158.17 0.00033778 17286000 2668.5 2437 2748 2563 2666.6 2991.3 2212.5 991.52 3163.8 2982.2 TRUE FALSE FALSE 2457.285409 2647.643421 2849.843297 2552.394985 2634.802537 2370.870661 2274.576795 1293.829884 2816.739055 3085.831228 0.796312315 0.858000074 0.923525328 0.827133695 0.853838834 0.768308597 0.737103434 0.419280832 0.912797508 1 11.59144344 -3.971766799 0.856972894 0.895378004 1.22E-28 0.853720674 0.057238803 1.295937122 0.502337363 0.012780181 1.22518576 0.000106717 3.971766799 -0.895378004 down VS(ph)EGGPAEIAGLQIGDK ddPTM_HeLa_Curcumin_4h_R1 3 VSEGGPAEIAGLQIGDK 17 0 O14907 O14907 TAX1BP3 Tax1-binding protein 3 1 0 VS(1)EGGPAEIAGLQIGDK;VS(1)EGGPAEIAGLQIGDK;VS(1)EGGPAEIAGLQIGDK ;; 194.94 1.15E-07 17056700 4525.5 6935.1 5763.9 4924.4 5188.6 7050.1 6830.6 3641.2 5799.9 6777.6 TRUE FALSE FALSE 4167.3019 7534.539142 5977.515204 4904.024138 5126.729334 5587.829789 7022.248252 4751.385118 5163.665481 7013.121096 0.594215021 1.07434893 0.852333094 0.699264147 0.731019651 0.796767903 1.00130144 0.677499369 0.736286371 1 12.77584092 VS(ph)EVEEEKEPVPQPLPSDDTR ddPTM_HeLa_Curcumin_4h_R1 1 VSEVEEEKEPVPQPLPSDDTR 21 1 O43290 O43290 SART1 U4/U6.U5 tri-snRNP-associated protein 1 1 0 VS(1)EVEEEKEPVPQPLPSDDTR 61.37 0.0044449 4913000 871.01 677.33 848.01 699.69 1213.4 1007.1 1108.1 1261 943.34 893.79 TRUE FALSE FALSE 802.0686394 735.8753871 879.4379966 696.7948682 1198.930997 798.2161076 1139.190304 1645.473095 839.8579621 924.849136 0.867242676 0.79567073 0.950898868 0.753414628 1.296353049 0.863077097 1.23175798 1.77918001 0.908102662 1 9.853074238 -3.280999297 0.963026337 0.925239393 6.073802574 0.767988345 0.14277258 3.584600032 0.614593293 0.020699649 30.07400572 0.000523601 3.280999297 5.148563181 VS(ph)FS(ph)T(ph)LNYIS(ph)LAFLTFS(ph)VVLALFLK ddPTM_HeLa_Curcumin_4h_R1 1 VSFSTLNYISLAFLTFSVVLALFLK 25 0 H3BTQ3;P41440-3;P41440-2;P41440 H3BTQ3 SLC19A1 Folate transporter 1 5 0 VS(0.977)FS(0.834)T(0.834)LNY(0.656)IS(0.677)LAFLT(0.615)FS(0.407)VVLALFLK 43.799 0.0078347 0 411.13 238.22 316.29 341.45 198.75 264.11 199.07 148.92 276.6 205.1 TRUE FALSE FALSE 378.5886267 258.8106753 328.0119856 340.0371704 196.3800361 209.3306089 204.6553684 194.3250225 246.257672 212.2272097 1.783883542 1.219498082 1.545569892 1.602231735 0.925329209 0.986351416 0.964322005 0.915646126 1.160349195 1 7.729465826 -5.746434026 24.98617985 1.395351474 0.951829831 0.49795643 0.21497324 215.5119186 358857.7916 0.04366811 0.087056591 1.79E-06 5.746434026 -0.443521643 VS(ph)GRTSPPLLDR ddPTM_HeLa_Curcumin_4h_R1 1 VSGRTSPPLLDR 12 1 Q9UQ35 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 VS(0.988)GRT(0.011)SPPLLDR 93.228 0.0057211 1202100000 4867.9 3485.6 3440.5 3937.9 3227.2 4308.5 3636 3373.9 5060.8 4279.4 TRUE FALSE FALSE 4482.600578 3786.879732 3568.007957 3921.606013 3188.717748 3414.868533 3738.016374 4402.586578 4505.642901 4428.108831 1.012305873 0.855191206 0.805763384 0.885616448 0.72010826 0.771179902 0.844156392 0.994236309 1.017509522 1 12.11247496 -7.217560109 4.560155893 1.00609696 0.831392787 0.566040011 0.068329477 0.10873303 5.181682417 0.011445565 0.013885897 6.06E-08 7.217560109 -0.174704173 VS(ph)LDVNHFAPDELTVK ddPTM_HeLa_Curcumin_4h_R1 2 VSLDVNHFAPDELTVK 16 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 1 0 VS(1)LDVNHFAPDELTVK;VS(1)LDVNHFAPDELTVK ; 127.78 0.00048284 11599700 2833.32 2278.89 2497.87 2513.39 3132.4 4059.4 2507.18 2735.59 2898.87 2319.57 TRUE FALSE FALSE 2609.059732 2475.867097 2590.44326 2502.990258 3095.048176 3217.434681 2577.524723 3569.658798 2580.871214 2400.174885 1.087029011 1.031536124 1.079272713 1.042836617 1.289509442 1.340500103 1.073890382 1.487249459 1.075284651 1 11.22892381 -1.000000009 0.25846732 1.011565499 3.546434397 0.575698684 0.100458083 24.14689166 0.303706673 0.048318011 27.24333511 0.099999998 1.000000009 2.534868897 VS(ph)LSEIGFGK ddPTM_HeLa_Curcumin_4h_R1 1 VSLSEIGFGK 10 0 H0YBX5;E5RJM2;E5RGN0;A0A087WZU2;Q00536;Q00536-3;Q00536-2 H0YBX5 CDK16 Cyclin-dependent kinase 16 1 0 VS(0.977)LS(0.023)EIGFGK 143 0.0013134 10526000 2605.4 2226.3 2379.4 2842.5 2304.6 2509 2044.7 1737.4 2533.9 2069.2 TRUE FALSE FALSE 2399.179841 2418.731452 2467.582657 2830.738488 2277.11915 1988.605118 2102.068779 2267.125262 2255.93751 2141.104546 1.12053372 1.129665273 1.152481163 1.322092606 1.063525438 0.928775347 0.981768397 1.058857806 1.053632581 1 11.06413953 -5.506843253 24.68575958 1.093001763 0.990189465 0.290063236 0.087681152 838.4535468 1290751.847 0.014824749 0.032267488 3.11E-06 5.506843253 -0.102812298 VS(ph)NSPEPQK ddPTM_HeLa_Curcumin_4h_R1 1 VSNSPEPQK 9 0 O60271-3;O60271;D6RHI8 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 VS(0.841)NS(0.159)PEPQK 128.51 0.0041524 13025000 5052.7 6340.9 6210.1 4292.6 5532.1 4488 2902.8 2802.6 4795.4 5180.5 TRUE FALSE FALSE 4652.773463 6888.979141 6440.251769 4274.838359 5466.133321 3557.13821 2984.244756 3657.099838 4269.356617 5360.521989 0.867970222 1.285132149 1.201422507 0.797466808 1.019701688 0.663580565 0.556707866 0.682228306 0.796444194 1 12.38815778 -5.209977682 5.1120924 0.977405689 0.619792716 0.538398569 0.152719595 0.127524957 7.546892425 0.021602455 0.055970166 6.17E-06 5.209977682 -0.357612972 VS(ph)PAHS(ph)PPENGLDK ddPTM_HeLa_Curcumin_4h_R1 2 VSPAHSPPENGLDK 14 0 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 2 0 VS(1)PAHS(1)PPENGLDK;VS(1)PAHS(1)PPENGLDK ; 123.92 0.00043391 0 7798.8 7264.9 7351 6444.1 8456.7 7608.3 6027.7 5275.4 6597.7 5392.2 TRUE FALSE FALSE 7181.516751 7892.845584 7623.434527 6417.436022 8355.859376 6030.252817 6196.821039 6883.845175 5873.948817 5579.578549 1.287107384 1.414595299 1.3663101 1.150165011 1.497578948 1.080772099 1.110625289 1.233757194 1.052758513 1 12.44594044 -9.129132315 0.945274134 1.003885422 1.266509898 0.361213249 0.127279426 0.460370303 0.757726826 0.078995897 0.024364367 7.43E-10 9.129132315 0.262624476 LREVIEIEDAS(ph)PTKCPITTK ddPTM_HeLa_Curcumin_4h_R1 2 LREVIEIEDASPTKCPITTK 20 2 P46100-5;P46100-3;P46100-4;P46100;P46100-2 P46100-5 ATRX Transcriptional regulator ATRX 1 0 LREVIEIEDAS(0.982)PT(0.016)KCPIT(0.001)TK;LREVIEIEDAS(0.988)PT(0.011)KCPIT(0.001)TK ; 113.51 0.0001289 206226000 5889.4 4282.2 4954.7 5340.5 4166.8 6191.3 3819.6 1842.84 5917.9 5164.3 TRUE FALSE FALSE 5423.247776 4652.334287 5138.325541 5318.402426 4117.113631 4907.15459 3926.767696 2404.713433 5268.721176 5343.759041 1.01487506 0.870610791 0.961556369 0.995254911 0.770452709 0.918296381 0.734832478 0.450004092 0.98595785 1 12.38363924 -3.968719707 0.653554437 0.994411743 4.55E-31 0.82568419 0.070151295 1.166952143 0.26508348 0.01180689 0.941644458 0.000107468 3.968719707 -0.994411743 down VS(ph)PENLVDK ddPTM_HeLa_Curcumin_4h_R1 3 VSPENLVDK 9 0 A0A088AWL3;O75376-2;O75376;E7EVK1;J3KS29;J3QKP0 A0A088AWL3 NCOR1 Nuclear receptor corepressor 1 1 0 VS(1)PENLVDK;VS(1)PENLVDK;VS(1)PENLVDK ;; 132.86 0.0034691 130188600 9310.3 9027.9 8701.4 8603.7 9969.3 10532.4 8603.7 3228.03 8760 7951 TRUE FALSE FALSE 8573.379931 9808.231448 9023.881539 8568.100169 9850.422609 8347.861515 8845.096666 4212.241487 7799.049916 8227.296658 1.042065248 1.192157261 1.09682219 1.041423511 1.197285453 1.014654249 1.075091495 0.511983664 0.947948061 1 13.00620275 -4.259987394 24.9823386 1.052530331 0.511983486 0.825495623 0.076344528 37.58324619 646577.915 0.010363245 0.08741831 5.50E-05 4.259987394 -0.540546845 APS(ph)VATVGSICDLNLK ddPTM_HeLa_Curcumin_4h_R1 2 APSVATVGSICDLNLK 16 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-5;O75369-4;A0A0C4DGA1 O75369-8 FLNB Filamin-B 1 0 APS(0.992)VAT(0.008)VGSICDLNLK;APS(1)VATVGSICDLNLK ; 157.42 0.00029047 220810000 2928.3 2925.4 3508.4 3097.3 4145.5 5212.5 4540 4434.6 2625.4 2438.69 TRUE FALSE FALSE 2696.521965 3178.258541 3638.42439 3084.484193 4096.06762 4131.368743 4667.380181 5786.689126 2337.400188 2523.434296 1.068592105 1.259497244 1.441854221 1.222335845 1.62321152 1.637200838 1.849614309 2.293180026 0.926277412 1 11.30117281 -1 0.264207236 0.96723498 10.0470114 0.943600633 0.096261043 6.642589022 0.083920646 0.043923527 27.65195762 0.1 1 9.079776421 up VS(ph)PPAS(ph)PGP ddPTM_HeLa_Curcumin_4h_R1 1 VSPPASPGP 9 0 A0A0C4DGU2;Q9Y4U1 A0A0C4DGU2 MMACHC Methylmalonic aciduria and homocystinuria type C protein 2 0 VS(1)PPAS(1)PGP 71.03 0.010401 6492100 3984.3 3645.9 3627.3 3477.8 3765.9 4278.7 3466.7 2705.9 3955.3 3608.9 TRUE FALSE FALSE 3668.938451 3961.03535 3761.730929 3463.409785 3720.994102 3391.249389 3563.966272 3530.916454 3521.413486 3734.309006 0.982494605 1.060714404 1.007343239 0.927456667 0.99643444 0.90813304 0.954384403 0.945534086 0.942989313 1 11.8666256 -6.26942486 24.87304399 0.998858869 0.947487766 0.36912121 0.034184482 416.3135852 1296724.553 0.004507691 0.006969349 5.38E-07 6.26942486 -0.051371103 VS(ph)PPASPGP ddPTM_HeLa_Curcumin_4h_R1 1 VSPPASPGP 9 0 A0A0C4DGU2;Q9Y4U1 A0A0C4DGU2 MMACHC Methylmalonic aciduria and homocystinuria type C protein 1 0 VS(1)PPASPGP 136.99 0.0016945 19948000 4927.6 3911.7 3549.4 4598.6 3627.6 5225.6 3843.5 4256.5 4512.1 4360.6 TRUE FALSE FALSE 4537.57526 4249.809918 3680.943886 4579.572212 3584.343239 4141.751655 3951.338266 5554.287255 4017.133919 4512.130525 1.005639184 0.941863249 0.815788432 1.01494675 0.794379333 0.917914859 0.875714531 1.230967771 0.890296479 1 12.13959309 -7.223084401 5.589438034 1.002713973 0.93014766 0 0.120430566 0.384235959 32.95312207 0.017898607 0.021743186 5.98E-08 7.223084401 -0.072566313 VS(ph)PPASPTLEVELGS(ph)AELPLQGAVGPELPPGGGHGR ddPTM_HeLa_Curcumin_4h_R1 1 VSPPASPTLEVELGSAELPLQGAVGPELPPGGGHGR 36 0 Q7Z6J0 Q7Z6J0 SH3RF1 E3 ubiquitin-protein ligase SH3RF1 2 0 VS(0.717)PPAS(0.205)PT(0.401)LEVELGS(0.678)AELPLQGAVGPELPPGGGHGR 54.904 0.0016136 4802200 409.72 321.68 526.61 527.08 449.49 681.53 446.74 367.91 350.86 260.45 TRUE FALSE FALSE 377.2902297 349.4845858 546.1266299 524.8990826 444.1301253 540.1729956 459.2743221 480.0840654 312.3715358 269.5006181 1.399960536 1.296785841 2.026439248 1.947673019 1.647974422 2.004347891 1.704167973 1.781383912 1.159075397 1 8.074144772 -7.480635455 0.660915829 1.072547757 1.856886334 0.733679551 0.178660663 0.225465084 0.216629745 0.05701747 0.057894235 3.31E-08 7.480635455 0.784338577 AQQCVS(ph)PSSSLCR ddPTM_HeLa_Curcumin_4h_R1 1 AQQCVSPSSSLCR 13 0 B9EGE7;Q8TCN5-2;Q8TCN5 B9EGE7 ZNF507 Zinc finger protein 507 1 0 AQQCVS(0.755)PS(0.219)S(0.02)S(0.006)LCR 209.22 2.77E-09 10669000 1269.8 907.23 1155.6 967.71 1101.2 1053.3 782.56 423.46 1482.2 1245.3 TRUE FALSE FALSE 1169.29399 985.6469187 1198.427553 963.7058724 1088.068909 834.8337069 804.5165274 552.5710046 1319.606368 1288.574082 0.907432492 0.764912885 0.93004164 0.7478855 0.844397636 0.647874048 0.624346352 0.428823622 1.024082656 1 10.33155977 -3.96852956 0.315611507 0.982003557 1.71E-16 0.862604175 0.065861286 2.044636167 0.127373805 0.024311386 0.796891023 0.000107515 3.96852956 -0.982003557 down VS(ph)PPQPPPPQPPRK ddPTM_HeLa_Curcumin_4h_R1 1 VSPPQPPPPQPPRK 14 1 Q15637-5 Q15637-5 SF1 Splicing factor 1 1 0 VS(1)PPQPPPPQPPRK 71.806 0.014231 14721000 1509 984.27 1126.3 1195.6 1619.7 1854.7 1262.8 1545.4 1486 1215.8 TRUE FALSE FALSE 1389.561058 1069.345913 1168.041669 1190.652924 1600.386135 1470.014313 1298.230769 2016.585346 1322.989518 1258.04896 1.10453655 0.850003416 0.928454859 0.94642813 1.27211753 1.168487365 1.031939782 1.602946635 1.051620056 1 10.29697235 -1.718363011 1.1214232 1.034606602 200 0.66229791 0.119035609 276.9180222 1.235616322 0.01842301 140654.0795 0.019126565 1.718363011 198.9653934 VS(ph)PSFSAELK ddPTM_HeLa_Curcumin_4h_R1 1 VSPSFSAELK 10 0 Q13416 Q13416 ORC2 Origin recognition complex subunit 2 1 0 VS(0.919)PS(0.079)FS(0.001)AELK 114.71 0.0055788 8619100 1600.9 1524 1425.9 1389.1 1431.6 1967.6 1660 1114.7 1383.1 1546.8 TRUE FALSE FALSE 1474.187076 1655.727769 1478.745108 1383.352272 1414.529105 1559.497581 1706.575132 1454.566899 1231.37739 1600.551185 0.921049629 1.034473489 0.923897419 0.864297428 0.883776238 0.974350333 1.066242147 0.908791242 0.769345837 1 10.6443531 -5.880181927 0.004851747 1.897323898 2.21E-07 0 0.089087132 40317.74753 61.291705 11784.98577 12184.03503 1.32E-06 5.880181927 -1.897323677 VS(ph)S(ph)IY(ph)KK ddPTM_HeLa_Curcumin_4h_R1 1 VSSIYKK 7 1 A0A1B0GWA6;Q99250-2;Q99250 A0A1B0GWA6 SCN2A Sodium channel protein type 2 subunit alpha 3 0 VS(1)S(1)IY(1)KK 44.638 0.0091735 0 369 424.7 560.42 403.59 618.53 693.83 481.83 511.74 726.38 963.75 TRUE FALSE FALSE 339.7932606 461.4091756 581.1896582 401.9200515 611.1544337 549.9218369 495.348853 667.7671702 646.6979313 997.2402408 0.340733603 0.462686078 0.58279804 0.403032324 0.61284574 0.551443689 0.49671968 0.669615147 0.648487601 1 9.96179729 -9.409778149 1.104739513 1.00350977 0.501162353 0.347557108 0.139948299 0.186402687 0.402395105 0.072885841 0.017963375 3.89E-10 9.409778149 -0.502347417 VS(ph)S(ph)S(ph)IQHPET(ph)PLHISGFHLPY(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 VSSSIQHPETPLHISGFHLPYK 22 0 Q9ULX3 Q9ULX3 NOB1 RNA-binding protein NOB1 5 0 VS(0.996)S(0.996)S(0.983)IQHPET(0.521)PLHIS(0.521)GFHLPY(0.982)K 43.955 0.020064 3793900 1875.5 1669.2 1723.2 1690.7 1674.2 2176.5 1330.8 824.84 2186.2 1930.4 TRUE FALSE FALSE 1727.052196 1813.47821 1787.063308 1683.704331 1654.236258 1725.069366 1368.138666 1076.329919 1946.37933 1997.481256 0.86461497 0.907882467 0.894658361 0.842913707 0.828161092 0.863622305 0.684931917 0.538843564 0.974416818 1 10.96396625 -3.539647463 0.451665713 0.939510631 1.87E-39 0.880850112 0.044649568 2.505589358 0.214908633 0.012695676 1.452153342 0.000288637 3.539647463 -0.939510631 VS(ph)S(ph)SY(ph)PVEPKK ddPTM_HeLa_Curcumin_4h_R1 1 VSSSYPVEPKK 11 1 Q9BTX1-4;Q9BTX1-6;Q9BTX1-5;Q9BTX1-2;Q9BTX1 Q9BTX1-4 NDC1 Nucleoporin NDC1 3 0 VS(0.733)S(0.733)S(0.733)Y(0.801)PVEPKK 51.211 0.0091632 0 5649.9 5033.4 4236.5 5659 5944.5 6860.3 5497.4 5286.6 6174.5 5351.6 TRUE FALSE FALSE 5202.704453 5468.464668 4393.508417 5635.584557 5873.61572 5437.396448 5651.642249 6898.460003 5497.172798 5537.567702 0.939528821 0.987521049 0.793400398 1.017700344 1.06068513 0.981910604 1.020600118 1.245756328 0.992705298 1 12.43503672 -1.000003533 0.945858972 0.965608423 191.6537545 0.604816776 0.066390146 627.1345885 1.047469407 0.010121918 258765.6496 0.099999186 1.000003533 190.6881461 VS(ph)SGYVPPPVATPFSSK ddPTM_HeLa_Curcumin_4h_R1 1 VSSGYVPPPVATPFSSK 17 0 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 0 VS(0.58)S(0.418)GY(0.001)VPPPVATPFSSK 118.2 0.00071954 62523000 5249.2 4878.1 4642.3 5447.1 5100.6 9139.1 6609.3 2063.4 6349.1 4076.9 TRUE FALSE FALSE 4833.720281 5299.741228 4814.347722 5424.561343 5039.778676 7243.547641 6794.73917 2692.521161 5652.619615 4218.571972 1.145819086 1.256287972 1.141226878 1.285876211 1.194664619 1.717061529 1.61067281 0.638254172 1.339936749 1 12.042539 -7.418532988 0.558109945 1.020180408 1.32786417 0 0.290229479 1.011298027 0.731583253 0.097372896 0.101568926 3.81E-08 7.418532988 0.307683762 VSADNTVGR ddPTM_HeLa_Curcumin_4h_R1 2 VSADNTVGR 9 0 O00303;H0YDT6 O00303 EIF3F Eukaryotic translation initiation factor 3 subunit F 0 0 ; ; 114.86 0.002036 4521000 2330.73 2213.5 2647.3 2556.4 2529.9 2839.7 2146.54 1991.58 2570.5 2192.9 FALSE FALSE TRUE 2146.250261 2404.825077 2745.411267 2545.822294 2499.732595 2250.71421 2206.766135 2598.803574 2288.522581 2269.103112 0.94585841 1.059813044 1.209910318 1.121950907 1.101639049 0.99189596 0.972527923 1.145299903 1.008558214 1 11.14790645 -7.143524339 5.385734275 0.97465426 1.086364339 0.326564073 0.067023035 0.192394331 7.836014841 0.011885852 0.014616873 7.19E-08 7.143524339 0.111710079 VSAEAEVAPVS(ph)PEVTQEVVEEHCAS(ph)PEDK ddPTM_HeLa_Curcumin_4h_R1 4 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 VSAEAEVAPVS(0.999)PEVT(0.001)QEVVEEHCAS(1)PEDK;VSAEAEVAPVS(0.997)PEVT(0.065)QEVVEEHCAS(0.938)PEDK;VSAEAEVAPVS(0.994)PEVT(0.007)QEVVEEHCAS(0.999)PEDK;VSAEAEVAPVS(0.975)PEVT(0.026)QEVVEEHCAS(0.999)PEDK ;;; 148.13 7.27E-12 521439000 14872.8 13569.4 13789.9 13325.6 15556 13591.6 8775.7 10136.5 13746.6 11978.2 TRUE FALSE FALSE 13695.60219 14742.27847 14300.96582 13270.4622 15370.50486 10772.54895 9021.922523 13227.07219 12238.63237 12394.44156 1.104979367 1.189426599 1.153820909 1.070678508 1.240112738 0.869143551 0.727900687 1.067177745 0.987429108 1 13.59740565 -5.227165593 24.03019133 1.082032131 0.872056522 0.449183121 0.108107748 277.8946158 194837.9617 0.015028702 0.038313041 5.93E-06 5.227165593 -0.209975609 VSAEAEVAPVS(ph)PEVTQEVVEEHCASPEDK ddPTM_HeLa_Curcumin_4h_R1 2 VSAEAEVAPVSPEVTQEVVEEHCASPEDK 29 0 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 VSAEAEVAPVS(0.959)PEVT(0.041)QEVVEEHCASPEDK;VSAEAEVAPVS(0.697)PEVT(0.303)QEVVEEHCASPEDK ; 147.74 7.46E-13 776450000 6995.7 5936.5 6124.3 6919.2 7084 6770.7 4527.3 5756.8 6390.6 5947 TRUE FALSE FALSE 6441.982963 6449.624607 6351.271945 6890.570184 6999.527927 5366.380498 4654.323853 7512.021819 5689.567168 6153.657807 1.046854272 1.048096077 1.03211328 1.119751926 1.137458101 0.872063522 0.756350775 1.220740908 0.924582963 1 12.58722851 -5.248136092 24.82428494 1.0395307 0.930381643 0.10482846 0.122057019 1004.209807 1873876.601 0.015289244 0.038734842 5.65E-06 5.248136092 -0.109149057 AQAYQT(ph)GKGIS(ph)T(ph)NY(ph)HASRK ddPTM_HeLa_Curcumin_4h_R1 1 AQAYQTGKGISTNYHASRK 19 2 Q58FF3 Q58FF3 HSP90B2P Putative endoplasmin-like protein 4 0 AQAY(0.485)QT(0.554)GKGIS(0.983)T(0.983)NY(0.994)HAS(0.002)RK 56.215 0.0085713 5700600 1026.9 877.77 926.03 944.6 1134.4 1368.8 1277.2 1185.4 1090.7 737.2 TRUE FALSE FALSE 945.6197814 953.6405275 960.3494864 940.6914955 1120.873021 1084.89545 1313.034795 1546.823003 971.0529388 762.8176451 1.239640676 1.250155307 1.258950278 1.233180042 1.469385282 1.422221231 1.721295781 2.027775594 1.272981747 1 9.575194406 -1 0.296545034 1.072252363 8.925250026 0.893176491 0.090904469 8.861755628 0.113352996 0.032361335 37.28114008 0.1 1 7.852997664 up VSAGEPGSHPS(ph)PAPR ddPTM_HeLa_Curcumin_4h_R1 2 VSAGEPGSHPSPAPR 15 0 A0A1B0GV68;C9JME2;Q9Y4F1;Q9Y4F1-2 A0A1B0GV68;C9JME2 FARP1 "FERM, RhoGEF and pleckstrin domain-containing protein 1" 1 0 VSAGEPGS(0.001)HPS(0.999)PAPR;VSAGEPGS(0.001)HPS(0.999)PAPR ; 134.83 0.00029885 131907000 7877.4 5652.2 5932.4 6919.2 8413.5 12228.4 5579.3 2703.2 10829.4 5494.7 TRUE FALSE FALSE 7253.895478 6140.750982 6152.259963 6890.570184 8313.174508 9692.091998 5735.840142 3527.393236 9641.441914 5685.640416 1.275827338 1.080045612 1.082069831 1.211925074 1.462135116 1.704661443 1.008829212 0.620403856 1.695753021 1 12.47310714 -9.458686083 1.067748519 0.994168795 1.204009221 0 0.346984976 1.352522086 2.630828015 0.223086902 0.049275185 3.48E-10 9.458686083 0.209840425 VSALEEDMDDVES(ph)S(ph)EEEEEEDEKLER ddPTM_HeLa_Curcumin_4h_R1 6 VSALEEDMDDVESSEEEEEEDEKLER 26 1 Q8NAV1 Q8NAV1 PRPF38A Pre-mRNA-splicing factor 38A 2 0 VSALEEDMDDVES(1)S(1)EEEEEEDEKLER;VSALEEDMDDVES(1)S(1)EEEEEEDEKLER;VSALEEDMDDVES(1)S(1)EEEEEEDEKLER;VSALEEDMDDVES(1)S(1)EEEEEEDEKLER;VSALEEDMDDVES(1)S(1)EEEEEEDEKLER;VSALEEDMDDVES(1)S(1)EEEEEEDEKLER ;;;;; 100.76 4.38E-06 207385000 11766.61 10128.31 10874.92 10947.97 10846.85 11996.21 10324.18 9623.45 10900.86 10817.9 TRUE FALSE FALSE 10835.2704 11003.75599 11277.9541 10902.6702 10717.5084 9508.060821 10613.8487 12557.5956 9705.062931 11193.82122 0.967968863 0.983020523 1.007516011 0.973990024 0.957448595 0.849402598 0.948188156 1.121832782 0.867001781 1 13.45041499 -5.959088003 5.092094135 0.986065203 0.95955131 0 0.073331285 0.609032802 37.52630521 0.009225658 0.016794776 1.10E-06 5.959088003 -0.026513892 VSAPGVQGDVK ddPTM_HeLa_Curcumin_4h_R1 1 VSAPGVQGDVK 11 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 0 0 106.16 0.0058548 3814000 779.77 618.15 664.19 760.53 852.24 829.87 709.11 750.49 1002.1 644.46 FALSE FALSE TRUE 718.0503817 671.5801316 688.8054657 757.3831284 842.0775946 657.7456074 729.0057181 979.3109462 892.1721371 666.854937 1.076771486 1.007085791 1.032916497 1.135753949 1.262759782 0.986339863 1.093199851 1.468551692 1.337880381 1 9.381229152 -4.266322957 4.288218627 1.054783568 1.498124889 0.414460466 0.118723631 0.087615633 3.738766501 0.011329437 0.117407615 5.42E-05 4.266322957 0.44334132 VSAS(ph)SPSLAVASQSDSK ddPTM_HeLa_Curcumin_4h_R1 2 VSASSPSLAVASQSDSK 17 0 A0A494C0P1;P04150-7;P04150-5;P04150-2;P04150-6;P04150-10;P04150;P04150-3;D6RDA9;Q3MSN4;P04150-9;P04150-8 A0A494C0P1 NR3C1 Glucocorticoid receptor 1 0 VS(0.002)AS(0.495)S(0.495)PS(0.008)LAVASQSDSK;VS(0.001)AS(0.389)S(0.389)PS(0.222)LAVASQSDSK ; 260.56 3.13E-41 48855000 8493.6 6235 6582.3 8611.7 7307.5 11200.7 10011.6 3719.63 8615.9 6032.4 TRUE FALSE FALSE 7821.322598 6773.925617 6826.245828 8576.067067 7220.362835 8877.548562 10292.49855 4853.728064 7670.757326 6242.025451 1.253010366 1.085212752 1.09359468 1.373923758 1.156733963 1.422222423 1.64890365 0.777588637 1.228889146 1 12.60779852 -6.272345064 23.50427211 1.117632303 1.298109851 0.090896152 0.219387549 484.3520232 1043889.82 0.032469546 0.049932232 5.34E-07 6.272345064 0.180477548 VSAS(ph)SPTTK ddPTM_HeLa_Curcumin_4h_R1 1 VSASSPTTK 9 0 Q9BVI0;Q5JWZ0;Q5JXL1 Q9BVI0 PHF20 PHD finger protein 20 1 0 VSAS(0.499)S(0.499)PTTK 153.1 0.0014487 25637000 7160 6611.9 7486.8 6565.3 7105.9 8198.3 6410.1 3952.5 6311.6 5860.5 TRUE FALSE FALSE 6593.278445 7183.403174 7764.267394 6538.134528 7021.166784 6497.880166 6589.950154 5157.599055 5619.233271 6064.151939 1.087254823 1.184568468 1.280355023 1.078161397 1.157815117 1.071523311 1.086705976 0.850506238 0.926631346 1 12.56609019 -2.978211795 9.820498781 1.07122848 0.667380897 0 0.118034653 0 0 0.014931354 0 0.001051449 2.978211795 -0.403847583 VSCHDS(ph)DDDIMR ddPTM_HeLa_Curcumin_4h_R1 1 VSCHDSDDDIMR 12 0 Q76FK4-2;Q76FK4-4;Q76FK4;F8WE42;F5H101;F5GWN9 Q76FK4-2 NOL8 Nucleolar protein 8 1 0 VSCHDS(1)DDDIMR 146.67 8.87E-05 0 2339.8 2023.3 1771.3 1823.8 2090.2 2874.9 1696.3 1025.6 1896.6 2157 TRUE FALSE FALSE 2154.602361 2198.185036 1836.945936 1816.253599 2065.27573 2278.613333 1743.893613 1338.300719 1688.547725 2231.955589 0.965342846 0.984869523 0.823020828 0.813749883 0.925321158 1.020904423 0.781329889 0.599609027 0.756532851 1 11.12409261 -4.495145725 3.038875966 0.957494797 0.60557236 0.459485627 0.094194597 0.1198716 2.023534188 0.010998699 0.076611999 3.20E-05 4.495145725 -0.351922436 VSCTNQLGQGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 VSCTNQLGQGKR 12 1 A0A2R8Y6S3;C9J167;P54278-2;P54278-3;P54278 A0A2R8Y6S3 PMS2 Mismatch repair endonuclease PMS2 0 1 VSCTNQLGQGK(1)R 166.29 6.08E-07 1291400 291.07 211.28 198.09 223.27 272.32 147.66 158.29 125.54 431.21 250.84 FALSE TRUE FALSE 268.0315024 229.5421018 205.4313897 222.3461679 269.0727619 117.0336515 162.7311914 163.8165681 383.9073418 259.5566713 1.032651178 0.884362173 0.791470274 0.856638231 1.036662862 0.45089826 0.626958231 0.631139887 1.479088709 1 8.019905759 -5.435820896 0.549391861 1.015734918 0.496300734 0.502967903 0.191734769 0.698870902 0.291320466 0.026884649 0.185527608 3.67E-06 5.435820896 -0.519434184 VSDEVGFGLEHVS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 VSDEVGFGLEHVSR 14 0 Q6VY07-2;Q6VY07 Q6VY07-2 PACS1 Phosphofurin acidic cluster sorting protein 1 1 0 VSDEVGFGLEHVS(1)R 71.073 0.014862 3733400 1909.1 1793.1 1969.7 2371.8 2650.6 4173.9 1456.7 383.41 2250.9 1501.7 TRUE FALSE FALSE 1757.992721 1948.087574 2042.698815 2361.98612 2618.993326 3308.18609 1497.571081 500.309944 2003.981901 1553.883963 1.131353925 1.25368922 1.314576161 1.52005309 1.685449743 2.128978848 0.963759918 0.321973813 1.289659942 1 10.60166306 -7.278174889 1.405484558 1.046922087 1.367750567 0.016463162 0.450060495 0.776533445 2.93571043 0.090703081 0.106919123 5.27E-08 7.278174889 0.32082848 VSDQNS(ph)PVLPK ddPTM_HeLa_Curcumin_4h_R1 4 VSDQNSPVLPK 11 0 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 0 VSDQNS(1)PVLPK;VSDQNS(1)PVLPK;VSDQNS(1)PVLPK;VSDQNS(1)PVLPK ;;; 115.24 0.004819 723820000 38165 34499.1 34941 35773 32823.9 35180.1 31955.7 28291 35364.2 34351.2 TRUE FALSE FALSE 35144.19998 37481.04848 36235.9442 35624.9808 32432.49643 27883.3507 32852.29094 36916.79566 31484.83574 35544.90164 0.988726888 1.054470451 1.019441397 1.002252901 0.912437366 0.784454293 0.924247625 1.038596084 0.88577642 1 15.11735502 -5.751288019 6.808527972 1.002144456 0.90586306 0.210864616 0.070341654 0.122154021 25.84194142 0.008749257 0.016989166 1.77E-06 5.751288019 -0.096281396 VSDQNS(ph)PVLPKK ddPTM_HeLa_Curcumin_4h_R1 3 VSDQNSPVLPKK 12 1 Q9UPU5 Q9UPU5 USP24 Ubiquitin carboxyl-terminal hydrolase 24 1 0 VSDQNS(1)PVLPKK;VSDQNS(1)PVLPKK;VS(0.002)DQNS(0.998)PVLPKK ;; 133.47 0.003189 286967000 18209.9 15475.2 15456 17285.9 12348.4 18160.1 12824.4 13234.5 19464.6 19665.2 TRUE FALSE FALSE 16768.5672 16812.80733 16028.81296 17214.37553 12201.1534 14393.49055 13184.21815 17269.63813 17329.38208 20348.56424 0.824066357 0.826240473 0.787712232 0.845974946 0.599607582 0.707346739 0.647918841 0.848690744 0.851626772 1 14.31263938 -8.279456909 0.296553601 1.057030698 0.688874465 0.391574641 0.085471107 0.935415151 0.20007638 0.132822078 0.058685045 5.25E-09 8.279456909 -0.368156233 VSDS(ph)ESEGPQKGPAS(ph)DS(ph)ETEDASR ddPTM_HeLa_Curcumin_4h_R1 1 VSDSESEGPQKGPASDSETEDASR 24 1 Q96ST2-3;Q96ST2 Q96ST2-3 IWS1 Protein IWS1 homolog 3 0 VS(0.381)DS(0.563)ES(0.062)EGPQKGPAS(0.726)DS(0.901)ET(0.366)EDAS(0.002)R 56.832 0.0055897 20644000 3851.2 2578.1 2434.1 3158.4 3118.6 3430.6 2450.4 2534.5 3171 2643.5 TRUE FALSE FALSE 3546.373456 2800.939476 2524.309887 3145.331378 3081.412732 2719.054889 2519.151629 3307.257383 2823.149233 2735.361428 1.296491725 1.02397418 0.922843271 1.149877799 1.126510267 0.994038616 0.920957502 1.209075096 1.032093677 1 11.41751576 VSDS(ph)LTDLALK ddPTM_HeLa_Curcumin_4h_R1 1 VSDSLTDLALK 11 0 Q8N3C0 Q8N3C0 ASCC3 Activating signal cointegrator 1 complex subunit 3 1 0 VS(0.002)DS(0.997)LT(0.001)DLALK 107.34 0.0076934 4577200 1935 2047.9 2254.9 2010.8 1868.3 2558.8 2044.1 2482.2 2563.4 1956.3 TRUE FALSE FALSE 1781.842708 2224.911351 2338.468578 2002.479842 1846.021743 2028.076036 2101.451945 3239.011353 2282.201433 2024.281279 0.880234741 1.099111756 1.155209309 0.989230036 0.911939344 1.001874619 1.038122501 1.600079686 1.127413199 1 10.98319406 -4.246474585 3.27720034 0.973306667 1.698625363 0.764530593 0.093264176 0.115222548 1.919189918 0.01293737 0.214546944 5.67E-05 4.246474585 0.725318696 VSEDEEKLPAS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 VSEDEEKLPASPK 13 1 Q7RTP6;J3QR21;J3QLA3 Q7RTP6 MICAL3 Protein-methionine sulfoxide oxidase MICAL3 1 0 VSEDEEKLPAS(1)PK 83.964 0.0079895 12861000 3927.2 3339.5 3756.2 3834 3925.9 4502.6 4170.1 5032.4 4588.8 3941.7 TRUE FALSE FALSE 3616.357976 3628.151499 3895.408076 3818.135924 3879.086207 3568.710005 4287.101783 6566.755594 4085.420121 4078.673782 0.886650458 0.889541967 0.955067329 0.936121918 0.95106557 0.874968236 1.051101905 1.610022263 1.001654052 1 11.99388441 -4.270774066 3.152841565 0.937884216 1.703204498 0.957608726 0.042269343 0.052486214 0.807642105 0.006742686 0.09768306 5.36E-05 4.270774066 0.765320282 VSEEAESQQQWDTSKGEQVSQNGLPAEQGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 VSEEAESQQQWDTSKGEQVSQNGLPAEQGSPR 32 1 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 1 0 VSEEAESQQQWDT(0.006)S(0.006)KGEQVS(0.038)QNGLPAEQGS(0.949)PR;VSEEAESQQQWDTSKGEQVSQNGLPAEQGS(1)PR ; 153.83 2.69E-14 30217700 5069.6 4082 4784.2 5157.6 4828.5 5915.3 4312.2 2930.77 6054.5 4524.9 TRUE FALSE FALSE 4668.335811 4434.829891 4961.506661 5136.259218 4770.923291 4688.400101 4433.188726 3824.348281 5390.336498 4682.139938 0.997051748 0.947180125 1.059666462 1.096989685 1.018962131 1.00133703 0.946829609 0.816794955 1.15125489 1 12.19295234 -4.292501401 1.989554741 1.008118089 0.767939613 0.533566701 0.059250878 0.314100719 1.381099523 0.005806562 0.133759762 5.10E-05 4.292501401 -0.240178476 VSEEQTQPPS(ph)PAGAGMS(ph)TAMGRS(ph)PSPK ddPTM_HeLa_Curcumin_4h_R1 1 VSEEQTQPPSPAGAGMSTAMGRSPSPK 27 1 X6RHM1;Q16666-3;Q16666-2;Q16666 X6RHM1 IFI16 Gamma-interferon-inducible protein 16 3 0 VSEEQT(0.006)QPPS(0.851)PAGAGMS(0.61)T(0.61)AMGRS(0.818)PS(0.105)PK 48.961 0.0085557 6698100 3209.4 2442 2319.2 3121.8 2784.6 3733.7 3296.4 1624.4 3560.5 2714.1 TRUE FALSE FALSE 2955.372603 2653.075599 2405.151592 3108.882819 2751.395464 2959.288533 3388.888112 2119.672082 3169.922058 2808.414773 1.05232768 0.944687951 0.856408966 1.106988486 0.979696977 1.053722036 1.206690744 0.754757489 1.128722897 1 11.45554031 VSEEQTQPPS(ph)PAGAGMSTAMGR ddPTM_HeLa_Curcumin_4h_R1 11 VSEEQTQPPSPAGAGMSTAMGR 22 0 X6RHM1;Q16666-3;Q16666-2;Q16666;H3BM18 X6RHM1 IFI16 Gamma-interferon-inducible protein 16 1 0 VSEEQT(0.021)QPPS(0.965)PAGAGMS(0.007)T(0.007)AMGR;VSEEQT(0.069)QPPS(0.93)PAGAGMSTAMGR;VSEEQTQPPS(0.49)PAGAGMS(0.255)T(0.255)AMGR;VSEEQT(0.002)QPPS(0.997)PAGAGMS(0.001)TAMGR;VSEEQT(0.002)QPPS(0.615)PAGAGMS(0.378)T(0.004)AMGR;VSEEQTQPPS(0.999)PAGAGMS(0.001)TAMGR;VSEEQTQPPS(1)PAGAGMSTAMGR;VSEEQTQPPS(0.641)PAGAGMS(0.356)T(0.003)AMGR;VSEEQTQPPS(0.844)PAGAGMS(0.142)T(0.015)AMGR;VSEEQTQPPS(1)PAGAGMSTAMGR;VSEEQTQPPS(1)PAGAGMSTAMGR ;;;;;;;;;; 171.83 1.22E-23 453609700 34464.6 24000.32 28205.7 35562 33088.2 38973.3 32438.7 23452.82 38148.5 31238.8 TRUE FALSE FALSE 31736.69054 26074.80072 29251.02805 35414.85387 32693.64483 30889.79826 33348.84262 30603.47685 33963.70499 32324.34597 0.981820036 0.806661355 0.904922503 1.095609294 1.01142479 0.955620209 1.031694273 0.946762446 1.050715922 1 14.98033356 -6.288959869 24.99514626 0.968503952 1.006781841 0.114961259 0.072743456 1800.883933 1635627.188 0.011403074 0.017421971 5.14E-07 6.288959869 0.038277889 VSEEQTQPPSPAGAGMS(ph)TAMGR ddPTM_HeLa_Curcumin_4h_R1 1 VSEEQTQPPSPAGAGMSTAMGR 22 0 X6RHM1;Q16666-3;Q16666-2;Q16666;H3BM18 X6RHM1 IFI16 Gamma-interferon-inducible protein 16 1 0 VSEEQTQPPS(0.083)PAGAGMS(0.459)T(0.459)AMGR 55.656 0.0063169 10908000 2757.4 2094 2274.5 2400.7 2393.3 3504.5 2924.8 2161.9 2789 2311.5 TRUE FALSE FALSE 2539.14888 2274.996029 2358.794971 2390.76654 2364.761461 2777.627196 3006.862016 2821.053358 2483.053678 2391.824453 1.061595 0.951155101 0.986190675 0.999557696 0.98868521 1.16130061 1.257141599 1.179456692 1.038142107 1 11.22389579 -5.128845221 3.940052748 1.015920566 1.216918969 0.867284242 0.0352182 0.068001675 1.818389279 0.005701278 0.015712065 7.43E-06 5.128845221 0.200998403 VSEFNVS(ph)SEGSGEK ddPTM_HeLa_Curcumin_4h_R1 1 VSEFNVSSEGSGEK 14 0 Q9BVJ6-3;Q9BVJ6 Q9BVJ6-3 UTP14A U3 small nucleolar RNA-associated protein 14 homolog A 1 0 VSEFNVS(0.944)S(0.056)EGSGEK 166.77 0.00021222 10782000 1454.5 1352 1319.1 1309.2 1554.2 2345.6 1732.4 926.61 1510.2 1203.5 TRUE FALSE FALSE 1339.37479 1468.860856 1367.987006 1303.782877 1535.66718 1859.09612 1781.006481 1209.129123 1344.534838 1245.321535 1.075525278 1.179503296 1.098501044 1.046944777 1.23314914 1.492864346 1.43015794 0.970937295 1.079668825 1 10.28230257 -5.651424181 4.096390444 1.05435927 1.318226362 0.336769405 0.136518362 0.153335031 4.691138534 0.019512115 0.040172745 2.23E-06 5.651424181 0.263867092 VSEMPAAK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 VSEMPAAKR 9 1 P35269;M0QXD6 P35269 GTF2F1 General transcription factor IIF subunit 1 0 1 ; VSEMPAAK(1)R;VSEMPAAK(1)R 94.309 0.0019357 0 5328.5 4239.4 5216.4 4595.6 4547.6 6530.3 4198.7 5398.2 5270.2 4600.1 FALSE TRUE FALSE 4906.743602 4605.834846 5409.724373 4576.584625 4493.37284 5175.842168 4316.504222 7044.08633 4692.072245 4759.953133 1.030838638 0.96762189 1.136507907 0.961476825 0.943995185 1.087372506 0.906837547 1.47986464 0.985739169 1 12.21673165 -4.253579323 24.98414199 1.011058422 1.479864869 0.828267585 0.065131081 256.9083065 816595.1395 0.007855316 0.114549541 5.58E-05 4.253579323 0.468806447 VSESPSPVTTNTPAQFASVSPT(ph)VPEFLK ddPTM_HeLa_Curcumin_4h_R1 1 VSESPSPVTTNTPAQFASVSPTVPEFLK 28 0 Q9ULH7-4;Q9ULH7;Q9ULH7-5;I3L2S3;Q9ULH7-2;Q9ULH7-3 Q9ULH7-4 MKL2 MKL/myocardin-like protein 2;Phosphatase and actin regulator 1 0 VSESPSPVT(0.001)T(0.001)NT(0.006)PAQFAS(0.309)VS(0.309)PT(0.375)VPEFLK 48.759 0.019944 8113500 1533.9 1168.4 1239.8 1451.4 1326.7 1190.9 673.21 947.63 1215.5 1471.3 TRUE FALSE FALSE 1412.490196 1269.39129 1285.748079 1445.394491 1310.879969 943.8939158 692.0984607 1236.558025 1082.162691 1522.427565 0.927788112 0.83379421 0.844538097 0.949401157 0.861045871 0.61999266 0.454601898 0.812227821 0.71081391 1 10.57215787 -5.351258332 3.232490979 0.942127298 0.608335568 0.412869926 0.120006844 0.103993026 2.077556011 0.013889418 0.034336748 4.45E-06 5.351258332 -0.33379173 VSETS(ph)RT(ph)T(ph)T(ph)TSLSPELIR ddPTM_HeLa_Curcumin_4h_R1 1 VSETSRTTTTSLSPELIR 18 1 A0A0U1RRJ0;A0A0U1RQC5;Q9HDB5;Q9Y4C0 A0A0U1RRJ0 NRXN3 "Neurexin-3-beta;Neurexin-3-beta, soluble form;Neurexin-3-beta, C-terminal fragment;Neurexin-3" 4 0 VS(0.001)ET(0.469)S(0.644)RT(0.883)T(0.962)T(0.384)T(0.258)S(0.225)LS(0.173)PELIR 59.513 0.0080801 24043000 865.62 1169.3 900.95 798.42 767.48 933.5 834.75 791.21 895.16 1030.1 TRUE FALSE FALSE 797.1052636 1270.369082 934.3399996 795.1163496 758.3283023 739.8815773 858.1708384 1032.446287 796.9631876 1065.895898 0.747826561 1.191832226 0.87657716 0.745960605 0.711446872 0.694140561 0.805116935 0.968618313 0.747693268 1 10.05785083 -6.361418606 5.845076089 0.906594124 0.77745469 0.176561725 0.138022081 0.347161076 16.8601239 0.022711093 0.03486395 4.35E-07 6.361418606 -0.129139434 VSFELFADK ddPTM_HeLa_Curcumin_4h_R1 1 VSFELFADK 9 0 P62937;F8WE65;C9J5S7 P62937 PPIA "Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase" 0 0 120.99 0.0012774 593250 595.72 529.73 670.35 429.34 475.87 480.76 431.61 408.75 463.84 296.19 FALSE FALSE TRUE 548.5681334 575.5175008 695.1937607 427.5635048 470.1955611 381.0449567 443.719815 533.3759933 412.9579125 306.4825805 1.789883564 1.877814719 2.268297793 1.395066252 1.534167326 1.243284222 1.447781516 1.740314221 1.347410714 1 8.259661268 -9.276789081 1.032986159 1.004518891 1.659690265 0.285572425 0.291260834 0.412738832 0.797353405 0.193528012 0.053839134 5.29E-10 9.276789081 0.655171374 VSFELFADK(ac)VPK ddPTM_HeLa_Curcumin_4h_R1 1 VSFELFADKVPK 12 1 P62937;F8WE65;C9J5S7 P62937 PPIA "Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase" 0 1 VSFELFADK(1)VPK 114.76 0.0017643 790890 417.79 273.63 298.47 111.82 234.38 546.75 556.38 445.72 663.59 257.59 FALSE TRUE FALSE 384.7214807 297.2813579 309.5315608 111.3573185 231.5851716 433.3478869 571.9905254 581.6179762 590.7958372 266.5412333 1.443384484 1.115329715 1.161289594 0.417786461 0.86885308 1.625819321 2.145973883 2.182093813 2.216526989 1 8.058214922 -4.958723477 3.25003524 1.123622251 2.163573387 0.448984456 0.434706812 0.113178555 2.447422465 0.04481078 0.150536919 1.10E-05 4.958723477 1.039951135 VSFELFADKVPK ddPTM_HeLa_Curcumin_4h_R1 3 VSFELFADKVPK 12 1 P62937;F8WE65;C9J5S7 P62937 PPIA "Peptidyl-prolyl cis-trans isomerase A;Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;Peptidyl-prolyl cis-trans isomerase" 0 0 ;; ;; 125.36 0.0026021 78494000 10110 7919.1 8298 8930.6 7089.6 12564.8 9345.8 9544.6 9867.8 9582 FALSE FALSE TRUE 9309.782832 8603.591717 8605.53118 8893.647543 7005.06115 9958.718846 9608.017995 12454.7046 8785.327028 9914.973787 0.938961921 0.867737213 0.867932822 0.896991534 0.70651333 1.00441202 0.96904119 1.256151037 0.886066591 1 13.27539324 -2.549462484 16.31968121 0.951879377 1.141898818 0 0.134087034 0 0 0.017022031 0 0.002821873 2.549462484 0.190019441 VSGAGFS(ph)PSSK ddPTM_HeLa_Curcumin_4h_R1 3 VSGAGFSPSSK 11 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 VSGAGFS(0.993)PS(0.006)SK;VSGAGFS(0.977)PS(0.023)SK;VSGAGFS(0.961)PS(0.039)SK ;; 185.57 8.44E-05 299424000 15584.3 12638.4 13051.5 12879.4 13081.7 16225.4 13669.7 10598.7 15419.9 12628.2 TRUE FALSE FALSE 14350.78621 13730.80698 13535.20007 12826.10846 12925.70927 12860.06914 14053.23499 13830.19484 13728.37555 13067.02901 1.098244 1.050797926 1.035828424 0.981562714 0.989185014 0.984161674 1.075472855 1.058403929 1.050611852 1 13.67364354 -6.513634875 22.2004657 1.047795537 1.016628462 0.148683075 0.036181626 202.0214277 485183.4822 0.00740353 0.010823699 3.06E-07 6.513634875 -0.031167074 VSGDTS(ph)FRLMK ddPTM_HeLa_Curcumin_4h_R1 1 VSGDTSFRLMK 11 1 O95206-2;O95206 O95206-2 PCDH8 Protocadherin-8 1 0 VS(0.01)GDT(0.085)S(0.905)FRLMK 115.71 0.0033535 0 861.34 601.49 644.35 929.36 687.27 966.86 954.72 726.1 869.9 1001.5 TRUE FALSE FALSE 793.1640301 653.4801154 668.2301778 925.5145546 679.0747541 766.3223372 981.5068737 947.4845474 774.4741464 1036.30205 0.765379196 0.630588461 0.644821823 0.893093432 0.65528651 0.739477778 0.947124319 0.914293808 0.747344026 1 10.01722885 -9.047371611 0.939492281 0.993781171 0.771766391 0 0.132019768 0.464012359 0.770130698 0.064971509 0.021915776 8.97E-10 9.047371611 -0.22201478 VSGEEELHTGPPAPQGPLSVPQGLPTQSLAS(ph)PPAR ddPTM_HeLa_Curcumin_4h_R1 1 VSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPAR 35 0 Q9UPN7 Q9UPN7 PPP6R1 Serine/threonine-protein phosphatase 6 regulatory subunit 1 1 0 VSGEEELHTGPPAPQGPLS(0.1)VPQGLPT(0.141)QS(0.103)LAS(0.656)PPAR 65.604 3.07E-05 13973000 1251.6 929.89 984.15 1090 1219.1 1862.9 1277.1 1471.9 1260.4 1261.2 TRUE FALSE FALSE 1152.534539 1010.265548 1020.623465 1085.489869 1204.563029 1476.513541 1312.931989 1920.675534 1122.137273 1305.026606 0.883150224 0.774134062 0.782071001 0.831776045 0.923017985 1.131404934 1.006057641 1.471752013 0.859857775 1 10.3498635 VSGGLEVLAEK ddPTM_HeLa_Curcumin_4h_R1 1 VSGGLEVLAEK 11 0 P39687;H0YN26;O43423 P39687 ANP32A;ANP32C Acidic leucine-rich nuclear phosphoprotein 32 family member A;Acidic leucine-rich nuclear phosphoprotein 32 family member C 0 0 103.31 0.0071174 1517700 594.62 487.12 800.77 424.23 591.81 744.26 410.16 501.92 648.23 435.8 FALSE FALSE TRUE 547.5551996 529.2244822 830.4472406 422.4746487 584.7530523 589.8920865 421.6679857 654.9530974 577.1207908 450.9440176 1.214242075 1.173592423 1.841575025 0.936867177 1.296730923 1.308127092 0.935078345 1.452404449 1.279805848 1 8.816804531 -8.597430577 0.829279294 1.016238487 1.266219633 0 0.25781735 0.805708962 1.125685156 0.104129864 0.049371015 2.53E-09 8.597430577 0.249981146 VSGGT(ph)PIKIEDPNQFVPLNTNPNEVLEK ddPTM_HeLa_Curcumin_4h_R1 1 VSGGTPIKIEDPNQFVPLNTNPNEVLEK 28 1 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 0 VS(0.327)GGT(0.673)PIKIEDPNQFVPLNTNPNEVLEK 57.738 0.0029398 10791000 2360.7 2096.9 1907 1754.4 2697.6 3065.8 3169.7 1307.7 2130.4 1803.9 TRUE FALSE FALSE 2173.848104 2278.146692 1977.675098 1747.140758 2665.432882 2429.918521 3258.633251 1706.41171 1896.70045 1866.585391 1.164612192 1.220488869 1.059514934 0.936009017 1.427972647 1.301798746 1.745772397 0.914188935 1.01613377 1 10.86618579 -5.750376463 24.96588264 1.081063784 1.372626431 0.308919066 0.204008555 182.3182317 411438.0025 0.027209801 0.054007904 1.78E-06 5.750376463 0.291562647 VSGGT(ph)PIKIEDPNQFVPLNTNPNEVLEKR ddPTM_HeLa_Curcumin_4h_R1 1 VSGGTPIKIEDPNQFVPLNTNPNEVLEKR 29 2 Q9UEY8-2;Q9UEY8 Q9UEY8-2 ADD3 Gamma-adducin 1 0 VS(0.331)GGT(0.669)PIKIEDPNQFVPLNTNPNEVLEKR 61.976 0.00071013 20208000 1586.8 1323.2 1455.2 1468.2 1342.8 2596.8 2493.1 674.43 2353.2 1442.3 TRUE FALSE FALSE 1461.203106 1437.571512 1509.130992 1462.124977 1326.787987 2058.194408 2563.049676 880.0606023 2095.059847 1492.419818 0.979083156 0.963248742 1.011197368 0.979700859 0.889017937 1.379098819 1.717378479 0.589687025 1.403800608 1 10.54343771 -5.262347463 24.99159392 0.982829586 1.277587149 0.06159125 0.294015588 87.28112442 2402131.434 0.033120964 0.078311757 5.47E-06 5.262347463 0.294757563 VSGLPTPDLSWQLDGKPVRPDS(ph)AHK ddPTM_HeLa_Curcumin_4h_R1 1 VSGLPTPDLSWQLDGKPVRPDSAHK 25 2 Q8WX93-3;Q8WX93;Q8WX93-8;Q8WX93-5;Q8WX93-2;Q8WX93-9;Q8WX93-4;Q8WX93-7 Q8WX93-3 PALLD Palladin 1 0 VSGLPT(0.001)PDLS(0.005)WQLDGKPVRPDS(0.993)AHK 53.482 0.0030232 56813000 1138.8 1237.9 1234.3 1256 1165.5 1591.8 1226.3 1241.4 1279.7 949.29 TRUE FALSE FALSE 1048.662778 1344.89856 1280.044244 1250.803005 1151.602174 1261.642737 1260.706678 1619.897145 1139.320112 982.2777568 1.067582739 1.369163203 1.303138786 1.273369977 1.172379366 1.284405279 1.283452332 1.64912331 1.159875711 1 9.93998722 -1 0.12974493 0.878707634 2.8971701 0.47567563 0.123034544 37.99418207 0.332645503 0.402404932 14.08079126 0.1 1 2.018462466 VSGS(ph)PEQAVEENLSSYSLDR ddPTM_HeLa_Curcumin_4h_R1 2 VSGSPEQAVEENLSSYSLDR 20 0 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 0 VS(0.196)GS(0.804)PEQAVEENLSSYSLDR;VS(0.269)GS(0.73)PEQAVEENLSSYSLDR ; 100.46 0.00053198 12010900 1937.39 1440.93 1716.68 1828.32 2266.73 2356.4 2105.96 2010.88 2044.87 1905.44 TRUE FALSE FALSE 1784.043537 1565.477569 1780.301671 1820.754896 2239.700725 1867.656078 2165.04757 2623.988055 1820.552877 1971.653898 0.9048462 0.793992074 0.902948369 0.923465776 1.135950243 0.947253511 1.098087028 1.330856322 0.923363314 1 10.94519061 -1.00000271 0.703151708 0.939894173 51.80982881 0.709353839 0.078652008 123.2442083 0.603112009 0.014013334 9875.704091 0.099999376 1.00000271 50.86993464 VSGS(ph)PEQAVEENLSSYSLDRR ddPTM_HeLa_Curcumin_4h_R1 2 VSGSPEQAVEENLSSYSLDRR 21 1 A0A494BZT8;Q9Y6A5;E7EMT0;C9JA91 A0A494BZT8 TACC3 Transforming acidic coiled-coil-containing protein 3 1 0 VS(0.074)GS(0.926)PEQAVEENLSSYSLDRR;VS(0.103)GS(0.867)PEQAVEENLS(0.013)S(0.004)Y(0.003)S(0.01)LDRR ; 112.42 1.26E-05 75353000 3195.73 2933.33 2616.15 3198.71 3289.12 4256.1 3137.07 3521.46 3366.53 2971.71 TRUE FALSE FALSE 2942.784598 3186.873975 2713.10682 3185.474586 3249.899392 3373.336884 3225.087741 4595.136943 2997.230082 3074.976701 0.957010373 1.036389633 0.882317846 1.035934544 1.056885859 1.097028437 1.048816968 1.4943648 0.974716355 1 11.58635976 -1.249584853 0.946425611 0.984661505 199.9999964 0.869510574 0.056465615 159.2176151 0.456924537 0.008243964 68338.16148 0.056287913 1.249584853 199.0153349 HAPS(ph)PEPAVQGTGVAGVPEESGDAAAIPAKK ddPTM_HeLa_Curcumin_4h_R1 3 HAPSPEPAVQGTGVAGVPEESGDAAAIPAKK 31 1 P13051 P13051 UNG Uracil-DNA glycosylase 1 0 HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAKK;HAPS(1)PEPAVQGTGVAGVPEESGDAAAIPAKK;HAPS(0.999)PEPAVQGT(0.001)GVAGVPEESGDAAAIPAKK ;; 107.65 1.05E-10 64292700 11442.9 8307 9876.3 9480.3 9353.4 11507.8 8415 3659.2 11835.2 9836.4 TRUE FALSE FALSE 10537.18239 9025.020065 10242.32437 9441.073031 9241.866814 9120.95256 8651.102252 4774.873235 10536.90817 10178.21417 1.035268291 0.88669976 1.006298767 0.927576574 0.90800475 0.896125038 0.849962686 0.469126819 1.035241349 1 13.31319683 -3.966696944 0.952764661 0.996914755 3.97E-37 0.87697369 0.055129162 0.779909941 0.370323056 0.008736079 0.912334645 0.00010797 3.966696944 -0.996914755 down VSHLLGINVTDFTR ddPTM_HeLa_Curcumin_4h_R1 3 VSHLLGINVTDFTR 14 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ;; ;; 134.06 0.00076569 22811800 3028.73 2137.98 2682.72 2147.97 2068.82 5374 3926.31 3123.59 2946.71 2622.76 FALSE FALSE TRUE 2789.002825 2322.777465 2782.143963 2139.082269 2044.150673 4259.371823 4036.471691 4075.958212 2623.463285 2713.900715 1.027673124 0.855881518 1.025145816 0.78819474 0.75321498 1.569464866 1.487332116 1.501881845 0.96667622 1 11.40615223 -5.250694185 24.95865965 0.969897105 1.516336909 0.877121838 0.102052129 202.1154815 469467.4241 0.015787365 0.039808077 5.61E-06 5.250694185 0.546439804 VSHS(ph)PALSSDVR ddPTM_HeLa_Curcumin_4h_R1 2 VSHSPALSSDVR 12 0 F8VWP4;F8W108;F8WCU9;Q68CP9-3;Q68CP9 F8VWP4 ARID2 AT-rich interactive domain-containing protein 2 1 0 VS(0.064)HS(0.936)PALSSDVR;VS(0.023)HS(0.977)PALSSDVR ; 83.856 0.0099202 18437900 5641 4305.8 4412.8 4960.5 5728.9 7878.7 6595.2 4612.5 5959.7 4589.1 TRUE FALSE FALSE 5194.508898 4677.974166 4576.34225 4939.974765 5660.586609 6244.568809 6780.243562 6018.830017 5305.93582 4748.570883 1.093909942 0.98513306 0.963730428 1.040307681 1.192061095 1.315041717 1.427849289 1.267503458 1.117375301 1 12.21327767 -5.496020183 2.256656458 1.033015759 1.349959958 0.850303982 0.057347323 0.080532365 0.80951205 0.008519582 0.021329742 3.19E-06 5.496020183 0.316944199 VSHYIINSSGPRPPVPPS(ph)PAQPPPGVSPSR ddPTM_HeLa_Curcumin_4h_R1 1 VSHYIINSSGPRPPVPPSPAQPPPGVSPSR 30 1 I3L297;P46108-2;P46108 I3L297 CRK Adapter molecule crk 1 0 VSHYIINS(0.002)S(0.002)GPRPPVPPS(0.993)PAQPPPGVS(0.002)PS(0.001)R 58.945 0.00079157 21129000 980.72 512.6 462.18 545.68 777.93 1312.4 727.09 824.93 795.59 587.65 TRUE FALSE FALSE 903.0949771 556.9068599 479.3087974 543.4221207 768.6536928 1040.193446 747.4901885 1076.447359 708.3157675 608.0707938 1.485180651 0.91585859 0.788245057 0.893682325 1.264085861 1.710645301 1.229281518 1.770266506 1.164857406 1 9.248095487 -5.459993448 6.550046998 1.147858593 1.531454911 0.463827119 0.237573341 0.249267952 21.06781553 0.041104786 0.092012974 3.47E-06 5.459993448 0.383596318 VSIGNITLS(ph)PAISR ddPTM_HeLa_Curcumin_4h_R1 2 VSIGNITLSPAISR 14 0 Q0JRZ9-3;Q0JRZ9 Q0JRZ9-3 FCHO2 F-BAR domain only protein 2 1 0 VSIGNIT(0.235)LS(0.765)PAISR;VSIGNITLS(0.999)PAIS(0.001)R ; 200.81 6.74E-09 123017000 2320.2 1872.42 2381.4 2199.29 2648.3 3101.5 2687.1 2898.2 2184.03 1856.92 TRUE FALSE FALSE 2136.553722 2034.263641 2469.656779 2190.189921 2616.720752 2458.213939 2762.492794 3781.847838 1944.447373 1921.447832 1.111949899 1.058713959 1.285310347 1.139864369 1.36184845 1.279355025 1.43771418 1.968228216 1.011969902 1 10.90797809 -1 0.41561597 1.05140438 16.33175518 0.894200244 0.089092901 14.01953733 0.161478352 0.020333912 179.356728 0.1 1 15.2803508 VSISEGDDKIEYR ddPTM_HeLa_Curcumin_4h_R1 1 VSISEGDDKIEYR 13 1 M0R0P1;M0R299;M0QXL5;M0R2Q4;P22087;M0R2U2;M0R1H0;M0R2B0 M0R0P1 FBL rRNA 2-O-methyltransferase fibrillarin 0 0 108.98 0.0036789 9740200 2670.9 2563.1 2471.7 2350.3 2542.4 2579 2521.7 1892.9 2763.6 2782.5 FALSE FALSE TRUE 2459.495447 2784.642943 2563.303376 2340.575081 2512.08354 2044.086329 2592.452115 2470.036496 2460.439994 2879.191668 0.854231232 0.967161365 0.890285772 0.812927846 0.872496114 0.70995146 0.900409703 0.857892347 0.854559292 1 11.49144812 -13.52287875 0.172466157 1.606199886 0.815493968 0.016777036 0.074960518 37.61248898 0.420959036 7.657802492 0.092752278 3.00E-14 13.52287875 -0.790705918 VSKQEEASGGPTAPK ddPTM_HeLa_Curcumin_4h_R1 1 VSKQEEASGGPTAPK 15 1 P50552;K7EM16 P50552 VASP Vasodilator-stimulated phosphoprotein 0 0 93.478 0.0039654 0 894.44 833.04 1053.3 849.88 622.34 965.26 584.77 692.13 1113.8 925.25 FALSE FALSE TRUE 823.6441302 905.0442656 1092.336225 846.3634217 614.919002 765.0541953 601.1770724 903.1572508 991.6189266 957.4023686 0.860290466 0.945312332 1.140937458 0.884020606 0.642278547 0.799093694 0.627925199 0.943341358 1.035738953 1 9.902981565 -5.965332956 9.238390488 0.950292589 0.749075498 0.500532994 0.109805283 0.227582697 56.8718552 0.015853686 0.028712285 1.08E-06 5.965332956 -0.20121709 LTPVSLSNS(ph)PIKGADCQEVPQDKDGYK ddPTM_HeLa_Curcumin_4h_R1 2 LTPVSLSNSPIKGADCQEVPQDKDGYK 27 2 P46100-5;P46100-3;P46100-4;P46100;P46100-2 P46100-5 ATRX Transcriptional regulator ATRX 1 0 LTPVS(0.009)LS(0.271)NS(0.72)PIKGADCQEVPQDKDGYK;LT(0.002)PVS(0.033)LS(0.265)NS(0.701)PIKGADCQEVPQDKDGYK ; 64.768 0.00036058 695340000 7234.8 5022.6 6034.1 6038.7 4858.6 6591.5 4339.9 2266.48 6664.6 6317.3 TRUE FALSE FALSE 6662.157946 5456.731164 6257.729054 6013.713459 4800.664368 5224.348598 4461.665914 2957.519318 5933.510054 6536.825705 1.019173257 0.834767731 0.957303948 0.919974577 0.734402994 0.799217974 0.682543197 0.452439678 0.907705104 1 12.67437451 -3.963473312 0.408833057 1.012167417 4.42E-17 0.823940185 0.068873012 1.477977879 0.14062818 0.015516895 0.766395581 0.000108774 3.963473312 -1.012167417 down VSLDVNHFAPDELTVK ddPTM_HeLa_Curcumin_4h_R1 2 VSLDVNHFAPDELTVK 16 0 P04792;F8WE04 P04792 HSPB1 Heat shock protein beta-1 0 0 ; ; 86.455 0.0065435 73452000 7592.4 6692.5 7114 6922.1 8527.2 14544.6 8908.8 7947 8555.2 7434.4 FALSE FALSE TRUE 6991.453529 7270.969879 7377.651098 6893.458184 8425.518709 11527.88601 9158.756951 10370.00372 7616.715964 7692.744847 0.908837309 0.94517237 0.95904014 0.896098639 1.095255189 1.498540019 1.190570743 1.348023875 0.990116807 1 12.90928274 -5.485277338 5.105724307 0.952368366 1.32893324 0.84403935 0.075941109 0.053117887 3.451364639 0.010384579 0.02304887 3.27E-06 5.485277338 0.376564874 VSLEDLYNGK ddPTM_HeLa_Curcumin_4h_R1 1 VSLEDLYNGK 10 0 O60884;A0A087WT48 O60884 DNAJA2 DnaJ homolog subfamily A member 2 0 0 112.71 0.0045427 736350 191.69 169.26 272.31 264.15 272.55 136.28 259.02 197.68 197.39 168.51 FALSE FALSE TRUE 176.5175342 183.8900802 282.4020481 263.0570173 269.3000193 108.0139918 266.2874041 257.951722 175.7368108 174.36571 1.012340868 1.054622954 1.61959624 1.508651084 1.544455153 0.619468081 1.527177586 1.479371845 1.007863363 1 7.445972543 -6.898942254 8.257241853 1.007312004 1.36752644 0.309122109 0.266940358 0.237608117 17.49779296 0.042605309 0.056062328 1.26E-07 6.898942254 0.360214435 VSLEPHQGPGT(ph)PESK ddPTM_HeLa_Curcumin_4h_R1 2 VSLEPHQGPGTPESK 15 0 A0A087WY61;Q14980-2;Q14980;Q14980-5;H0YFY6 A0A087WY61 NUMA1 Nuclear mitotic apparatus protein 1 1 0 VSLEPHQGPGT(0.885)PES(0.115)K;VSLEPHQGPGT(0.997)PES(0.003)K ; 126.4 0.0007996 118430000 4808.79 4142.19 3556.4 3320.59 5721.7 9393.81 5101.69 1752.45 5765.3 3830.19 TRUE FALSE FALSE 4428.169197 4500.222446 3688.203313 3306.850278 5653.472464 7445.427916 5244.829691 2286.763938 5132.861014 3963.288817 1.117296619 1.135476785 0.930591608 0.834370249 1.426459873 1.878598371 1.323352885 0.576986448 1.29510143 1 11.95248239 -5.74665609 24.99614716 1.039140063 1.344153184 0.121486094 0.318988167 319.2107066 539730.4531 0.044401525 0.088505279 1.79E-06 5.74665609 0.305013122 VSLLGPVT(ph)TPEHQLLK ddPTM_HeLa_Curcumin_4h_R1 2 VSLLGPVTTPEHQLLK 16 0 Q9H0H5 Q9H0H5 RACGAP1 Rac GTPase-activating protein 1 1 0 VSLLGPVT(0.753)T(0.247)PEHQLLK;VSLLGPVT(0.725)T(0.275)PEHQLLK ; 123.76 0.0020478 79105000 6184.6 4086 4634.8 5255.3 4862.4 7353.4 5024.6 1414.9 6827.6 4787.7 TRUE FALSE FALSE 5695.082384 4439.175633 4806.569765 5233.554961 4804.419056 5828.22195 5165.576753 1846.296497 6078.629362 4954.072219 1.149575972 0.896065991 0.970226019 1.056414749 0.969791889 1.176450745 1.042693066 0.372682596 1.226996518 1 12.27439918 -4.261786053 7.547844016 1.051851147 0.365513702 0.81306195 0.098045862 0.027973985 15.70392014 0.012281904 0.09786284 5.47E-05 4.261786053 -0.686337444 VSLPS(ph)SPVPASPASSSGADQR ddPTM_HeLa_Curcumin_4h_R1 1 VSLPSSPVPASPASSSGADQR 21 0 Q5T6S3-2 Q5T6S3-2 1 0 VSLPS(0.856)S(0.143)PVPAS(0.001)PASSSGADQR 182.72 5.19E-10 10981000 3453.9 2693.1 3738.1 3002.3 2958.4 3733 3187.4 3569.3 3107.2 2634.2 TRUE FALSE FALSE 3180.52017 2925.879564 3876.637274 2989.877278 2923.123012 2958.73372 3276.829866 4657.563139 2766.347934 2725.738254 1.166847244 1.07342646 1.422233873 1.096905498 1.072415155 1.085479765 1.202180679 1.708734554 1.014898599 1 11.41243131 -4.258679558 2.976887507 1.105998177 1.811105414 0.711426174 0.112316046 0.166777739 2.118832169 0.016504483 0.279808785 5.51E-05 4.258679558 0.705107237 EFSGPST(ph)PTGTLEFEGGEVSLEGGK ddPTM_HeLa_Curcumin_4h_R1 1 EFSGPSTPTGTLEFEGGEVSLEGGK 25 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 EFS(0.004)GPS(0.177)T(0.694)PT(0.107)GT(0.018)LEFEGGEVSLEGGK 104.05 3.77E-07 64360000 6311.3 5937.7 6864 6399.2 7311.9 9229.7 8927.7 9110.7 5751.7 5137.5 TRUE FALSE FALSE 5811.753945 6450.92833 7118.385878 6372.721806 7224.710368 7315.35618 9178.187234 11888.51049 5120.7529 5316.027743 1.093251244 1.213486581 1.339042274 1.198775122 1.359043014 1.376094433 1.726512291 2.236352229 0.963266775 1 12.37613292 -1 0.396976453 1.044608811 19.72157333 0.942957863 0.086369422 9.600429422 0.113895397 0.021726594 141.4698453 0.1 1 18.67696452 up VSNS(ph)PEPQK ddPTM_HeLa_Curcumin_4h_R1 3 VSNSPEPQK 9 0 O60271-3;O60271;D6RHI8 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 VS(0.195)NS(0.805)PEPQK;VS(0.002)NS(0.998)PEPQK;VS(0.004)NS(0.996)PEPQK ;; 161.19 0.00066998 77870000 15221.2 17895.5 16898.9 13441.3 16902.1 12989.8 7701.8 8424.4 12345.8 13459.7 TRUE FALSE FALSE 14016.42596 19442.30728 17525.1881 13385.68346 16700.5535 10295.56905 7917.89178 10992.96078 10991.49663 13927.42357 1.006390441 1.395973001 1.258322331 0.961102633 1.199112916 0.73922998 0.568510876 0.789303256 0.789198129 1 13.76564078 -5.149211953 5.52658824 1.06066597 0.674587168 0.521885669 0.169253746 0.132640004 5.610148976 0.022335018 0.058369727 7.09E-06 5.149211953 -0.386078803 VSNS(ph)PEPQKAVEQEDELSDVSQGGSK ddPTM_HeLa_Curcumin_4h_R1 1 VSNSPEPQKAVEQEDELSDVSQGGSK 26 1 O60271-3;O60271;D6RHI8 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 VS(0.272)NS(0.728)PEPQKAVEQEDELSDVSQGGSK 108.94 6.56E-08 27979000 1409.7 1082.9 1269.8 1384.9 1101.5 1216.6 620.74 644.66 1396.6 1618.1 TRUE FALSE FALSE 1298.120757 1176.501051 1316.859905 1379.169651 1088.365332 964.2634461 638.1562938 841.2138664 1243.396474 1674.328855 0.775308121 0.702670236 0.786500156 0.823714915 0.650030804 0.575910427 0.381141549 0.502418545 0.742623811 1 10.7093672 -4.565626466 0.183953183 1.041536448 2.45E-15 0.631167957 0.101356378 4.488541465 0.166751095 0.145205314 1.119921987 2.72E-05 4.565626466 -1.041536448 VSNS(ph)PPLGR ddPTM_HeLa_Curcumin_4h_R1 1 VSNSPPLGR 9 0 H0Y9Y2 H0Y9Y2 BOD1L1 1 0 VS(0.055)NS(0.945)PPLGR 94.82 0.016167 18920000 1537.6 1185.4 1359.7 1231.6 1109.3 1462.4 1225.3 946.33 1619.6 1154.7 TRUE FALSE FALSE 1415.897338 1287.860694 1410.091678 1226.503966 1096.072322 1159.081755 1259.67862 1234.861661 1441.933932 1194.825739 1.185024135 1.077864873 1.180165134 1.026512842 0.917349105 0.970084354 1.054278109 1.03350775 1.206815258 1 10.22258451 -6.012973052 24.49714384 1.09541451 0.993367645 0.431135085 0.06976879 498.8733533 942029.6573 0.012078712 0.020683642 9.71E-07 6.012973052 -0.102046865 VSPAS(ph)PAGS(ph)PSADFAVHGESLGDR ddPTM_HeLa_Curcumin_4h_R1 1 VSPASPAGSPSADFAVHGESLGDR 24 0 A0A0A0MRP9;Q96C92-4;Q96C92-3;Q96C92-2;Q96C92 A0A0A0MRP9 SDCCAG3 Serologically defined colon cancer antigen 3 2 0 VS(0.032)PAS(0.967)PAGS(0.979)PS(0.021)ADFAVHGESLGDR 126.18 1.99E-06 65011000 1765.4 1488.6 1721.4 1646.4 2140 2590.3 1369.4 789.17 2141.9 1383.4 TRUE FALSE FALSE 1625.666727 1617.267951 1785.196598 1639.587633 2114.481898 2053.042581 1407.821678 1029.7843 1906.938929 1431.473047 1.135660033 1.129792806 1.247104584 1.145384914 1.477137067 1.434216722 0.983477601 0.719387838 1.332151473 1 10.48328479 -8.470968697 0.740660537 1.009820591 1.178733327 0 0.226523416 1.216317733 1.389538921 0.100032939 0.048903601 3.38E-09 8.470968697 0.168912736 VSPAS(ph)PAGSPSADFAVHGESLGDR ddPTM_HeLa_Curcumin_4h_R1 2 VSPASPAGSPSADFAVHGESLGDR 24 0 A0A0A0MRP9;Q96C92-4;Q96C92-3;Q96C92-2;Q96C92 A0A0A0MRP9 SDCCAG3 Serologically defined colon cancer antigen 3 1 0 VS(0.01)PAS(0.989)PAGS(0.001)PSADFAVHGESLGDR;VS(0.084)PAS(0.825)PAGS(0.087)PS(0.004)ADFAVHGESLGDR ; 139.47 1.29E-06 45589000 3431.2 2743.11 2414.31 2855.5 3119.5 3882.6 2557.4 2419.36 3553.2 2752.15 TRUE FALSE FALSE 3159.616899 2980.212205 2503.786452 2843.684698 3082.302 3077.304994 2629.153761 3157.011727 3163.42285 2847.787008 1.109499022 1.046501089 0.879204254 0.998559474 1.082349906 1.080595208 0.923226967 1.108584216 1.110835481 1 11.47562553 -6.970034894 24.9995017 1.053091755 1.009499904 0.106193934 0.073521349 458.8174031 382784.5082 0.012317392 0.016188166 1.07E-07 6.970034894 -0.043591851 VSPGRTS(ph)DPNPAAPDSESVIVAMER ddPTM_HeLa_Curcumin_4h_R1 1 VSPGRTSDPNPAAPDSESVIVAMER 25 1 P42858 P42858 HTT Huntingtin 1 0 VS(0.208)PGRT(0.179)S(0.613)DPNPAAPDSESVIVAMER 90.912 8.39E-06 9499500 1841 1521.7 1717.7 1735.2 1621.7 1720.1 1372.6 1002.8 1485.9 1501 TRUE FALSE FALSE 1695.282907 1653.228967 1781.359473 1728.020202 1602.362287 1363.33187 1411.111462 1308.549104 1322.900488 1553.159638 1.091505899 1.064429519 1.146926194 1.112583768 1.031679067 0.877779616 0.908542449 0.842507796 0.851747918 1 10.60099041 -5.302210116 4.198230061 1.059319914 0.877835319 0.484076636 0.077810618 0.088973725 3.498712332 0.007687759 0.018553712 4.99E-06 5.302210116 -0.181484596 VSPLNLSSVT(ph)P ddPTM_HeLa_Curcumin_4h_R1 2 VSPLNLSSVTP 11 0 Q9UJX2;Q9UJX2-3 Q9UJX2 CDC23 Cell division cycle protein 23 homolog 1 0 VSPLNLSSVT(1)P;VSPLNLSSVT(1)P ; 151.79 0.0014544 15730100 4206.2 3487.7 3508.7 3885.7 4012.9 5021.2 4211.2 5733.1 4425.8 3632.5 TRUE FALSE FALSE 3873.274832 3789.161247 3638.735509 3869.622003 3965.048788 3979.746519 4329.354938 7481.095798 3940.300813 3758.729105 1.03047459 1.008096392 0.968076019 1.029502764 1.05489081 1.058801102 1.151813503 1.990325876 1.048306676 1 11.87602923 -4.220569164 2.617597191 1.017296006 2.251302736 0.990688078 0.027898583 0.038159777 0.305927102 0.004160027 0.107259405 6.02E-05 4.220569164 1.23400673 VSPPAPGS(ph)APETPEDK ddPTM_HeLa_Curcumin_4h_R1 2 VSPPAPGSAPETPEDK 16 0 M0R0P8;Q13459-2;Q13459;M0R300 M0R0P8 MYO9B Unconventional myosin-IXb 1 0 VSPPAPGS(1)APETPEDK;VS(0.042)PPAPGS(0.956)APET(0.002)PEDK ; 199.33 5.60E-08 30187000 2719.2 3435 2776 3163.6 2470.2 2662.5 2283.31 1405.26 3285.8 2725.7 TRUE FALSE FALSE 2503.972451 3731.906094 2878.881002 3150.509861 2440.744478 2110.267487 2347.373533 1833.717305 2925.355961 2820.417872 0.887801937 1.323174885 1.020728535 1.117036554 0.865383992 0.748210933 0.832278634 0.650158022 1.037206575 1 11.46169321 -5.520653176 4.858750421 0.994207625 0.758211516 0.541334081 0.124463988 0.14697465 9.65761224 0.01955583 0.042100311 3.02E-06 5.520653176 -0.235996109 VSPS(ph)FSAELK ddPTM_HeLa_Curcumin_4h_R1 1 VSPSFSAELK 10 0 Q13416 Q13416 ORC2 Origin recognition complex subunit 2 1 0 VS(0.386)PS(0.613)FS(0.001)AELK 112.64 0.0064681 13268000 1119.7 1220.9 1321.4 1116.3 1395.5 1646.4 1024.2 913.26 1452 1116.4 TRUE FALSE FALSE 1031.074563 1326.429156 1370.372246 1111.681046 1378.859574 1304.918081 1052.936296 1191.70877 1292.719233 1155.194817 0.8925547 1.148229837 1.186269386 0.962332093 1.193616482 1.12960867 0.911479415 1.031608481 1.119048678 1 10.17392046 -7.264600013 24.92851036 0.949261942 1.079720736 0.029561207 0.105130771 251.1783523 1981090.18 0.016163759 0.018901537 5.44E-08 7.264600013 0.130458794 VSPS(ph)KSPS(ph)LSPSPPS(ph)PLEKTPLGER ddPTM_HeLa_Curcumin_4h_R1 1 VSPSKSPSLSPSPPSPLEKTPLGER 25 2 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 3 0 VS(0.04)PS(0.451)KS(0.455)PS(0.531)LS(0.394)PS(0.13)PPS(0.636)PLEKT(0.363)PLGER 53.522 0.0083268 9733900 703.55 627.92 539.58 782.59 873.69 981.5 645.86 813.32 1162.3 862.15 TRUE FALSE FALSE 647.8632751 682.1946068 559.5773095 779.3518499 863.2718174 777.9258362 663.9810934 1061.297524 1034.798598 892.1096483 0.726214851 0.76469816 0.627251718 0.873605449 0.967674567 0.872006975 0.744281933 1.189649194 1.159945529 1 9.801077231 -4.250593297 24.24570065 0.845427677 1.189649497 0.306570541 0.147586927 881.4262533 1970311.789 0.018682063 0.356861507 5.62E-05 4.250593297 0.34422182 VSPSKS(ph)PSLS(ph)PSPPSPLEK ddPTM_HeLa_Curcumin_4h_R1 1 VSPSKSPSLSPSPPSPLEK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 VS(0.219)PS(0.316)KS(0.459)PS(0.019)LS(0.77)PS(0.21)PPS(0.006)PLEK 86.617 0.0020736 50835000 5826.3 4866.4 4496.7 5791.5 5548.2 5537 2749.7 1849 5711.7 4578.2 TRUE FALSE FALSE 5365.142207 5287.029932 4663.351658 5767.536308 5482.041339 4388.563785 2826.849182 2412.751588 5085.1408 4737.292109 1.132533541 1.116044738 0.984391832 1.217475337 1.157209902 0.926386569 0.596722583 0.509310284 1.073427748 1 12.20984692 -4.816732204 2.739939254 1.079058994 0.521880217 0.908722123 0.06818179 0.062706202 0.927562814 0.011152915 0.046880068 1.52E-05 4.816732204 -0.557178778 VSPSKS(ph)PSLSPSPPS(ph)PLEK ddPTM_HeLa_Curcumin_4h_R1 2 VSPSKSPSLSPSPPSPLEK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 2 0 VS(0.07)PS(0.33)KS(0.485)PS(0.041)LS(0.074)PS(0.03)PPS(0.97)PLEK;VS(0.078)PS(0.367)KS(0.515)PS(0.04)LS(0.002)PS(0.008)PPS(0.99)PLEK ; 86.248 0.0021411 121256000 6184.4 4982.3 5946.8 5813.3 5644.4 5670.8 4772.5 7836.5 5598 5093.5 TRUE FALSE FALSE 5694.898214 5412.947811 6167.193639 5789.246105 5577.094216 4494.612157 4906.403505 10225.81278 4983.913406 5270.498746 1.080523588 1.027027625 1.170134732 1.098424719 1.058172003 0.852786875 0.930918257 1.940198313 0.945624626 1 12.36372377 -4.257449361 24.99870792 1.034472715 1.940198664 0.907170935 0.088344482 85.2550243 534127.841 0.012251548 0.12544607 5.53E-05 4.257449361 0.905725949 VSPSKSPSLSPSPPS(ph)PLEK ddPTM_HeLa_Curcumin_4h_R1 1 VSPSKSPSLSPSPPSPLEK 19 1 P46821 P46821 MAP1B Microtubule-associated protein 1B;MAP1B heavy chain;MAP1 light chain LC1 1 0 VSPSKSPSLS(0.003)PS(0.032)PPS(0.964)PLEK 68.303 0.0049809 21370000 1368.6 831.25 660.99 778.42 670.43 1640.3 1807.4 2066 1893.9 1435.5 TRUE FALSE FALSE 1260.273866 903.099546 685.4868709 775.1991043 662.4355601 1300.08329 1858.11078 2695.913889 1686.143908 1485.383518 0.848450148 0.607990822 0.461488136 0.521884816 0.445969376 0.875250919 1.250929983 1.814961494 1.135157276 1 10.53661976 -4.448159116 2.196333628 0.803401116 1.888265392 0.687428715 0.227471564 0.229729657 1.648088956 0.036792014 0.41313814 3.56E-05 4.448159116 1.084864276 CGERDELS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 CGERDELSPK 10 1 H0Y4C5;B8ZZS2;Q13506-2;Q13506 H0Y4C5 NAB1 NGFI-A-binding protein 1 1 0 CGERDELS(1)PK 71.888 0.0183 42148000 3439.9 3514.6 3021 3074.1 3575.2 3942.6 3143.2 1400.6 3559.1 3622.2 TRUE FALSE FALSE 3167.628285 3818.386363 3132.960918 3061.380189 3532.568075 3124.860318 3231.389733 1827.636492 3168.675634 3748.07118 0.845135573 1.018760365 0.835886184 0.816788167 0.942502932 0.833724913 0.862147376 0.48762054 0.84541501 1 11.87193264 -3.957087586 1.545798397 0.91583865 4.66E-18 0.734161699 0.071554611 0.994099446 1.194819388 0.011242294 1.729374603 0.000110386 3.957087586 -0.91583865 down VSQGSAESLS(ph)PSFR ddPTM_HeLa_Curcumin_4h_R1 2 VSQGSAESLSPSFR 14 0 Q86YV5 Q86YV5 SGK223 Tyrosine-protein kinase SgK223 1 0 VSQGSAES(0.029)LS(0.967)PS(0.004)FR;VSQGSAES(0.153)LS(0.763)PS(0.084)FR ; 95.073 0.0074618 58796000 2427.3 2209.7 2524.2 2541.8 2558.3 2985.6 2038.86 1544.34 3094.8 2240.8 TRUE FALSE FALSE 2235.176644 2400.696622 2617.749073 2531.282705 2527.793943 2366.352905 2096.064924 2015.202157 2755.308183 2318.667633 0.963991825 1.03537764 1.128988491 1.091697089 1.090192448 1.020565807 0.903995421 0.869120752 1.188315282 1 11.17908032 -4.695372208 4.43363077 1.014343399 0.878575974 0.344661552 0.07655104 0.164928512 6.215962681 0.009378844 0.037604563 2.02E-05 4.695372208 -0.135767425 VSQGVEDGPDTK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 VSQGVEDGPDTKR 13 1 A0A590UK93;A0A590UKC5;B3KNJ4;Q9UBE0-2;Q9UBE0-3;Q9UBE0;M0QYM8;M0R054;M0QX65 A0A590UK93 SAE1 "SUMO-activating enzyme subunit 1;SUMO-activating enzyme subunit 1, N-terminally processed" 0 1 ; VSQGVEDGPDTK(1)R;VSQGVEDGPDTK(1)R 236.08 1.46E-102 2033100 1124.13 1208.3 1040.33 1158.43 1584.92 2194.92 1532.28 1373.67 1702.81 1075.03 FALSE TRUE FALSE 1035.153924 1312.740068 1078.885545 1153.636724 1566.020864 1739.66885 1575.271653 1792.495659 1516.016003 1112.387212 0.930569781 1.180110714 0.969883088 1.037081972 1.40780193 1.563905833 1.416118088 1.61139542 1.362849183 1 10.11944335 -5.720991778 3.086369219 0.98576784 1.517176508 0.650675176 0.143264477 0.052032441 1.013563292 0.011834322 0.024496884 1.90E-06 5.720991778 0.531408669 VSQLLAVTGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VSQLLAVTGKK 11 1 J3KS23;Q13951 J3KS23 CBFB Core-binding factor subunit beta 0 1 ; VSQLLAVTGK(1)K;VSQLLAVTGK(1)K 178.71 4.83E-12 20998200 7904.6 5510.1 7617.2 6265.2 6508.3 10012 8449.4 6398.2 6543.9 6091.6 FALSE TRUE FALSE 7278.942569 5986.368491 7899.500133 6239.276262 6430.692773 7935.398342 8686.467424 8348.981726 5826.050542 6303.282647 1.154786002 0.949722363 1.253235905 0.989845548 1.020213297 1.258931066 1.378086294 1.324545034 0.924288322 1 12.62188764 -5.094283502 3.841453931 1.069867795 1.346965801 0.637386425 0.096162905 0.108130205 2.890569131 0.012534676 0.035312561 8.05E-06 5.094283502 0.277098006 VSQSALNPHQS(ph)PDFKR ddPTM_HeLa_Curcumin_4h_R1 2 VSQSALNPHQSPDFKR 16 1 Q9NYL2 Q9NYL2 ZAK Mitogen-activated protein kinase kinase kinase MLT 1 0 VSQSALNPHQS(1)PDFKR;VSQSALNPHQS(1)PDFKR ; 83.359 0.0048366 70058000 4463.8 3645.4 3417.6 3974.3 4098.1 6275.1 4156.2 1243.36 4893.6 3941.4 TRUE FALSE FALSE 4110.48552 3960.492132 3544.259262 3957.8554 4049.232834 4973.573525 4272.811786 1622.45474 4356.784323 4078.363357 1.007876239 0.971098401 0.869039601 0.970451883 0.992857301 1.219502308 1.047678054 0.397820056 1.068267818 1 11.9937746 -4.259060215 24.87954804 1.006276745 0.397819828 0.825469465 0.085205119 61.03835036 638250.0087 0.011688821 0.104893033 5.51E-05 4.259060215 -0.608456917 VSQSPS(ph)KDSEENPATEERPEK ddPTM_HeLa_Curcumin_4h_R1 1 VSQSPSKDSEENPATEERPEK 21 2 D6RC71;D6RF48;Q9P2W9 D6RC71 STX18 Syntaxin-18 1 0 VS(0.005)QS(0.073)PS(0.917)KDS(0.005)EENPATEERPEK 74.657 0.0025432 0 433.95 299.52 387.83 432.13 280.53 505.76 315.59 386.98 419.19 405.16 TRUE FALSE FALSE 399.6023996 325.4091742 402.203321 430.3419606 277.184863 400.8596749 324.444606 504.9684206 373.2059058 419.2392798 0.953160686 0.776189612 0.959364593 1.026482921 0.661161481 0.956159631 0.773888854 1.204487377 0.890197851 1 8.711630084 -7.498587485 12.48942336 0.979362754 0.899273985 0.001949402 0.145646624 1.979640795 1014.785444 0.022882007 0.024969279 3.17E-08 7.498587485 -0.080088769 VSS(ph)AEGAAKEEPK ddPTM_HeLa_Curcumin_4h_R1 1 VSSAEGAAKEEPK 13 1 P05114;F2Z2W6;F2Z2Y5;H7BXJ5;A0A494C035 P05114 HMGN1 Non-histone chromosomal protein HMG-14 1 0 VS(0.006)S(0.994)AEGAAKEEPK 139.77 0.0095864 4361900 1108.3 1113.8 847.32 1110.7 1060.1 1517.3 1108.5 722.53 1065.4 1108.6 TRUE FALSE FALSE 1020.576886 1210.071909 878.7224246 1106.104218 1047.459 1202.594877 1139.601527 942.8260709 948.5282855 1147.123767 0.889683323 1.05487476 0.766022333 0.964241391 0.913117686 1.048356691 0.99344252 0.821904399 0.826875279 1 10.16380534 -9.587802638 1.362106121 1.000180496 0.9301516 0 0.102037337 0.915759387 3.03460838 0.05888197 0.01354033 2.58E-10 9.587802638 -0.070028895 VSS(ph)GYVPPPVATPFSSK ddPTM_HeLa_Curcumin_4h_R1 1 VSSGYVPPPVATPFSSK 17 0 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 0 VS(0.128)S(0.868)GY(0.003)VPPPVATPFSSK 115.8 0.00081987 68431000 1395.9 1213.5 1448.4 1437.3 1489.1 2596.7 1530.6 632.72 1723.6 1220.6 TRUE FALSE FALSE 1285.413042 1318.389533 1502.078978 1431.352833 1471.343455 2058.115149 1573.544517 825.6334153 1534.525392 1263.015759 1.017733178 1.043842504 1.18927968 1.133281848 1.164944653 1.62952452 1.245862932 0.653700011 1.214969315 1 10.30265692 -6.809760997 2.051670604 1.007477569 1.196691484 0.009490671 0.230994815 0.494611585 4.260318962 0.03707785 0.052097818 1.55E-07 6.809760997 0.189213915 VSS(ph)PAGPTEDNDLSR ddPTM_HeLa_Curcumin_4h_R1 2 VSSPAGPTEDNDLSR 15 0 H3BN63;Q86YC2 H3BN63 PALB2 Partner and localizer of BRCA2 1 0 VS(0.04)S(0.96)PAGPTEDNDLSR;VS(0.092)S(0.908)PAGPTEDNDLSR ; 180.85 5.36E-05 17221500 5736.5 5077.2 5390.7 5243.2 5520.5 6352.4 4659.3 3248.1 6334.7 4906.2 TRUE FALSE FALSE 5282.449972 5516.050544 5590.484084 5221.505028 5454.671643 5034.840634 4790.027418 4238.430738 5639.799259 5076.690085 1.040530323 1.086544668 1.101206493 1.028525465 1.07445433 0.991756548 0.94353355 0.834880733 1.110920534 1 12.30967248 -4.427936037 1.580255933 1.034796155 0.79861394 0.743012386 0.040570165 0.305718847 0.906963343 0.005702494 0.10025295 3.73E-05 4.427936037 -0.236182215 VSS(ph)PAPMEGGEEEEELLGPK ddPTM_HeLa_Curcumin_4h_R1 3 VSSPAPMEGGEEEEELLGPK 20 0 O14497;O14497-2;H0Y488;A0A1B0GTU5;O14497-3 O14497 ARID1A AT-rich interactive domain-containing protein 1A 1 0 VS(0.058)S(0.942)PAPMEGGEEEEELLGPK;VS(0.16)S(0.84)PAPMEGGEEEEELLGPK;VS(0.03)S(0.97)PAPMEGGEEEEELLGPK ;; 168.83 1.41E-06 25711500 9272.9 8297.4 9203.1 8351.7 10498.1 9363.8 8786.3 9834.1 7889.2 7204.5 TRUE FALSE FALSE 8538.94018 9014.590284 9544.174982 8317.142878 10372.91701 7421.642328 9032.819931 12832.47182 7023.774498 7454.855839 1.145419893 1.209223958 1.28026285 1.115667836 1.391430933 0.995544715 1.211669297 1.721357475 0.942174423 1 12.86396474 -4.277261897 3.578163095 1.117192782 1.781493325 0.63899253 0.130739224 0.122211826 2.800469396 0.018067566 0.211978876 5.28E-05 4.277261897 0.664300543 VSS(ph)PLSPLSPGIKS(ph)PTIPR ddPTM_HeLa_Curcumin_4h_R1 2 VSSPLSPLSPGIKSPTIPR 19 1 Q9P2B4 Q9P2B4 CTTNBP2NL CTTNBP2 N-terminal-like protein 2 0 VS(0.208)S(0.816)PLS(0.146)PLS(0.169)PGIKS(0.613)PT(0.048)IPR;VS(0.191)S(0.796)PLS(0.063)PLS(0.379)PGIKS(0.424)PT(0.146)IPR ; 95.223 0.0010459 47165000 2707.8 2616.6 2714.5 2854.3 2684.9 2860.5 2438.2 1857 3104.2 2703.2 TRUE FALSE FALSE 2493.474773 2842.767245 2815.101758 2842.489663 2652.884321 2267.200056 2506.60933 2423.190751 2763.677026 2797.135999 0.891438519 1.01631356 1.006422912 1.016214322 0.948428794 0.810543376 0.896134236 0.866311382 0.988038132 1 11.44973469 -5.38374409 6.472854318 0.962912406 0.862011937 0.615634994 0.04310288 0.177035032 8.640590485 0.007790547 0.017548782 4.13E-06 5.38374409 -0.100900469 VSS(ph)PSPATDGK ddPTM_HeLa_Curcumin_4h_R1 1 VSSPSPATDGK 11 0 A8MW92;A0A0A0MQS0;F8W9L8;A8MW92-4 A8MW92 PHF20L1 PHD finger protein 20-like protein 1 1 0 VS(0.334)S(0.632)PS(0.031)PAT(0.004)DGK 90.434 0.017008 5300000 4741.3 4285.1 5505 4220.7 5076.2 5146.3 5420.8 4732.4 4784.5 4904.3 TRUE FALSE FALSE 4366.021102 4655.48495 5709.020143 4203.235862 5015.66963 4078.899369 5572.893059 6175.286975 4259.65232 5074.72406 0.860346504 0.917386816 1.124991246 0.82826885 0.988363026 0.803767716 1.098166717 1.216871479 0.839385998 1 12.30911366 -4.560944989 6.132047932 0.934608006 1.189952838 0.519153735 0.093588565 0.090392377 9.086068157 0.012334783 0.049175107 2.75E-05 4.560944989 0.255344832 VSS(ph)PTVNTTLR ddPTM_HeLa_Curcumin_4h_R1 2 VSSPTVNTTLR 11 0 Q9NSK0-5;Q9NSK0;Q9NSK0-3 Q9NSK0-5 KLC4 Kinesin light chain 4 1 0 VS(0.005)S(0.991)PT(0.005)VNTTLR;VS(0.147)S(0.85)PT(0.003)VNT(0.001)TLR ; 126.66 0.0033323 50405000 7998 7452.3 7554 7732.3 8701.9 9691.2 6854.9 5924.7 8283.1 7080.1 TRUE FALSE FALSE 7364.949861 8096.443605 7833.957885 7700.305791 8598.135526 7681.135878 7047.230045 7731.113756 7374.464653 7326.132948 1.005298418 1.105145602 1.069316915 1.051073717 1.173625375 1.048457069 0.961930407 1.055278932 1.006597165 1 12.83883617 -7.345557587 8.87478544 1.002404674 1.065311598 0.249106214 0.04963771 0.397410016 39.29985618 0.008752726 0.009995367 4.51E-08 7.345557587 0.062906923 T(ph)KSPTDDEVTPSAVVR ddPTM_HeLa_Curcumin_4h_R1 1 TKSPTDDEVTPSAVVR 16 1 A0A1B0GUN5;Q5VTI5;Q9Y2H5 A0A1B0GUN5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 0 T(0.423)KS(0.288)PT(0.288)DDEVTPSAVVR 127.05 0.0048256 9486500 3325.4 2623.5 2808.7 3125.4 2968.3 3408.5 2340 1195.1 3218.7 3077.1 TRUE FALSE FALSE 3062.191081 2850.26365 2912.792893 3112.467923 2932.904961 2701.538678 2405.654102 1559.480488 2865.616663 3184.028996 0.961734672 0.895175155 0.914813557 0.977524993 0.921130104 0.848465476 0.75553775 0.489782125 0.899997037 1 11.63663776 -3.954016054 0.825683247 0.970861492 1.27E-13 0.922709895 0.039418345 0.590360511 0.208401969 0.00596938 0.587823201 0.000111169 3.954016054 -0.970861492 down EISS(ph)VDCIALVDTIDNS(ph)S(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 EISSVDCIALVDTIDNSSK 19 0 Q9UBT6-3;Q9UBT6-8;Q9UBT6 Q9UBT6-3 POLK DNA polymerase kappa 3 0 EIS(0.465)S(0.522)VDCIALVDT(0.015)IDNS(0.998)S(1)K 58.418 0.0095138 0 288.63 195.1 262.28 296.59 213.82 388.5 320.43 303.65 236.98 186.14 TRUE FALSE FALSE 265.7846309 211.9635747 272.0003275 295.3627892 211.2703362 307.9207207 329.4204034 396.2314872 210.9838869 192.6083511 1.379922674 1.100490053 1.412193843 1.533489007 1.09689084 1.598688317 1.710312151 2.057187473 1.095403629 1 7.589526447 -1 0.294453742 1.129981511 8.387957979 0.756409928 0.157655606 19.87792302 0.25421881 0.069046486 76.55647831 0.1 1 7.257976468 up VSS(ph)SPGVK ddPTM_HeLa_Curcumin_4h_R1 1 VSSSPGVK 8 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 0 VS(0.014)S(0.493)S(0.493)PGVK 117.31 0.0091143 4635700 4162.5 4744.7 4440.1 3473 4493.7 4424.7 3185.2 1752.6 4431.6 4147.1 TRUE FALSE FALSE 3833.033733 5154.810726 4604.654012 3458.629646 4440.115562 3506.967343 3274.568139 2286.959672 3945.464567 4291.211416 0.893228825 1.201248372 1.073042916 0.805979783 1.034699793 0.817244131 0.763087115 0.53294034 0.919429081 1 12.06716927 -4.242005281 0.970296696 0.973644767 0.289829916 0.654279532 0.104894837 1.01249518 0.703724629 0.016580325 0.729631899 5.73E-05 4.242005281 -0.683814851 VSSAEGAAKEEPK ddPTM_HeLa_Curcumin_4h_R1 2 VSSAEGAAKEEPK 13 1 P05114;F2Z2W6;F2Z2Y5;H7BXJ5;A0A494C035 P05114 HMGN1 Non-histone chromosomal protein HMG-14 0 0 ; ; 93.649 0.0070206 8850500 6886.1 5594.7 5399.2 6667.3 6170.4 6485.4 5298.5 5313.8 7246.1 6566.2 FALSE FALSE TRUE 6341.057919 6078.280939 5599.299102 6639.712479 6096.82201 5140.254934 5447.16165 6933.953158 6451.220959 6794.374961 0.933280538 0.894604871 0.82410805 0.977236687 0.897333757 0.756545667 0.801716373 1.020543199 0.949494397 1 12.73012512 -7.863420097 0.530117252 0.997989455 0.866906386 0.178819135 0.075701925 0.723383868 0.486702981 0.036625648 0.025799911 1.37E-08 7.863420097 -0.13108307 VSSGYVPPPVAT(ph)PFSSK ddPTM_HeLa_Curcumin_4h_R1 2 VSSGYVPPPVATPFSSK 17 0 Q15942;Q15942-2;H7C3R3 Q15942 ZYX Zyxin 1 0 VSSGY(0.001)VPPPVAT(0.98)PFS(0.007)S(0.011)K;VSSGYVPPPVAT(0.981)PFS(0.015)S(0.004)K ; 119.96 0.0018727 8394700 2710.3 2341.8 3024.8 3069.4 3090.7 6349.1 6128.5 2877.9 2857.4 1990.01 TRUE FALSE FALSE 2495.776895 2544.214757 3136.901749 3056.699636 3053.845421 5032.225091 6300.449216 3755.358462 2543.950369 2059.162699 1.212034822 1.235557908 1.52338703 1.484438134 1.48305203 2.443821021 3.059714134 1.823730812 1.235429512 1 11.00784211 -5.403616106 2.015726053 1.165813939 2.533927708 0.711124421 0.325908342 0.115993375 0.912796945 0.047674791 0.132828062 3.95E-06 5.403616106 1.368113769 EMPQDLRS(ph)PAR ddPTM_HeLa_Curcumin_4h_R1 2 EMPQDLRSPAR 11 1 O43765;K7EMD6 O43765 SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha 1 0 EMPQDLRS(1)PAR;EMPQDLRS(1)PAR ; 92.611 0.0068193 145550000 4939.3 4610.1 4789 4525.7 5132.8 6366.9 5080.5 6141.3 4543.1 3707.6 TRUE FALSE FALSE 4548.349193 5008.576502 4966.484553 4506.973853 5071.594712 5046.33317 5223.045157 8013.754099 4044.733296 3836.438824 1.185565417 1.30552753 1.29455591 1.174780587 1.321953756 1.315369123 1.361430586 2.08885231 1.054293704 1 11.90555203 -1 0.623901495 1.123374678 67.5653739 0.846284178 0.111234871 53.15047646 0.349166514 0.022341195 4858.893089 0.1 1 66.44199923 up AAHVPENS(ph)DTEQDVLTVKPVRK ddPTM_HeLa_Curcumin_4h_R1 1 AAHVPENSDTEQDVLTVKPVRK 22 2 H3BSS6;Q9H2Y7;A0A0C4DGM5;Q9H2Y7-2;H3BS99 H3BSS6 ZNF106 Zinc finger protein 106 1 0 AAHVPENS(0.824)DT(0.17)EQDVLT(0.006)VKPVRK 44.816 0.01336 19010000 2587.9 1845 2324.9 2238.7 1987.6 2415.1 1823.5 802.51 2908.1 2118 TRUE FALSE FALSE 2383.064984 2004.473579 2411.062839 2229.436853 1963.899168 1914.181036 1874.662502 1047.191605 2589.088706 2191.600342 1.087362937 0.914616383 1.10013801 1.017264329 0.896102784 0.873417018 0.855385202 0.477820515 1.181369 1 11.09776902 -3.952889847 0.769521756 1.033766344 1.60E-15 0.811104573 0.080488445 1.020224729 0.31352138 0.010761884 1.009798778 0.000111458 3.952889847 -1.033766344 down VSSQFDPNKQTPSGK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 VSSQFDPNKQTPSGKK 16 2 Q01780-2;Q01780 Q01780-2 EXOSC10 Exosome component 10 0 1 VSSQFDPNKQTPSGK(1)K 86.777 0.004598 2366900 1540.6 1212.4 1088.9 1326.5 938.21 1936.4 1167.7 863.06 1922.8 1759.2 FALSE TRUE FALSE 1418.659884 1317.194454 1129.255592 1321.011294 927.0224585 1534.768812 1200.462519 1126.203021 1711.873651 1820.332069 0.779341258 0.723601191 0.620356918 0.725697974 0.509260082 0.843125734 0.659474466 0.618679987 0.940418333 1 10.82998594 -8.333499546 0.513146431 1.00887317 0.657262104 0.665476101 0.083643904 0.358327384 0.205274516 0.055847194 0.024904667 4.64E-09 8.333499546 -0.351611066 VSSS(ph)PGVK ddPTM_HeLa_Curcumin_4h_R1 2 VSSSPGVK 8 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 0 VSS(0.129)S(0.87)PGVK;VSS(0.006)S(0.994)PGVK ; 172.59 0.00097735 33672000 10336.9 12457.4 10643.6 8445 10531.3 12055.8 9005.3 4431.3 8880.9 10462.5 TRUE FALSE FALSE 9518.723458 13534.16215 11038.06118 8410.056828 10405.72113 9555.291183 9257.964481 5782.382971 7906.687489 10826.0711 0.879240804 1.250145323 1.019581442 0.776833696 0.961172436 0.882618551 0.855154598 0.534116479 0.730337665 1 13.40222215 -3.883032826 1.106434917 0.960749932 2.50E-12 0.439678267 0.135977337 2.101476617 1.175823843 0.017843386 2.873860433 0.000130908 3.883032826 -0.960749932 VSSSESDFS(ph)DAEGGMQSK ddPTM_HeLa_Curcumin_4h_R1 1 VSSSESDFSDAEGGMQSK 18 0 A0A087WXZ7;K7EIX2;Q6AI08;K7ELR8 A0A087WXZ7 HEATR6 HEAT repeat-containing protein 6 1 0 VSSSES(0.002)DFS(0.997)DAEGGMQSK 111.77 0.0021987 0 248.22 331.46 328.84 430.04 422.6 455.04 378.61 209.94 395.97 340.29 TRUE FALSE FALSE 228.5731251 360.1099254 341.0270997 428.2606084 417.560771 360.6595746 389.2327776 273.9497396 352.5330817 352.1150522 0.649143295 1.022705287 0.968510427 1.21625192 1.185864587 1.02426628 1.105413629 0.77801201 1.001187196 1 8.45990309 -7.076662076 9.555140153 0.834209881 1.056657405 0.172636473 0.148535099 0.462396412 55.42927265 0.028099853 0.034443824 8.38E-08 7.076662076 0.222447525 VSTGDTSPCGTEEDSSPAS(ph)PMHER ddPTM_HeLa_Curcumin_4h_R1 1 VSTGDTSPCGTEEDSSPASPMHER 24 0 B0QY16;Q6ICG6-3;Q6ICG6;Q6ICG6-2 B0QY16 KIAA0930 Uncharacterized protein KIAA0930 1 0 VSTGDTSPCGTEEDSS(0.001)PAS(0.999)PMHER 154.46 5.19E-12 0 1738.5 1326.7 1110.2 1369.6 1378.5 1482.9 1177.5 907.72 1676.3 1469.2 TRUE FALSE FALSE 1600.895891 1441.374036 1151.344989 1363.932958 1362.062288 1175.329824 1210.537481 1184.479649 1492.414084 1520.254591 1.053044602 0.948113589 0.757336959 0.897174043 0.895943545 0.773113814 0.796272867 0.779132427 0.981686944 1 10.57009723 -6.954750107 4.620975637 1.02426896 0.821414465 0.769825954 0.0486575 0.065907175 3.129737291 0.008148122 0.010689294 1.11E-07 6.954750107 -0.202854496 VSTLPAITLK ddPTM_HeLa_Curcumin_4h_R1 2 VSTLPAITLK 10 0 H7C1V0;H7C469;A0A1B0GW44;A0A1B0GV23;A0A1B0GVD5;A0A1B0GWE8;A0A1B0GU92;A0A1B0GU03;P07339 H7C1V0 CTSD Cathepsin D;Cathepsin D light chain;Cathepsin D heavy chain 0 0 ; ; 159.37 7.44E-09 1143660 1260.27 795.82 1564 694.46 1308.77 3688.7 2331.06 2066.92 1232.7 1040.61 FALSE FALSE TRUE 1160.5183 864.6071347 1621.963216 691.5865085 1293.163773 2923.62204 2396.46327 2697.114393 1097.475894 1076.77112 1.077776213 0.802962783 1.506321247 0.642278099 1.200964391 2.715175013 2.225601361 2.504816802 1.019228575 1 10.07249591 -5.317608997 5.759749747 1.030749558 2.455454506 0.884777479 0.239396987 0.042308309 3.09677715 0.030076719 0.068830834 4.81E-06 5.317608997 1.424704948 up GAS(ph)QAGMTGYGMPR ddPTM_HeLa_Curcumin_4h_R1 1 GASQAGMTGYGMPR 14 0 P37802;P37802-2;C9J5W6;Q9UI15 P37802 TAGLN2;TAGLN3 Transgelin-2;Transgelin-3 1 0 GAS(0.993)QAGMT(0.007)GYGMPR 68.277 0.015436 7092100 2109.2 1645.7 2067.3 2015.9 2119.4 3051 2646.5 3119 2507.7 1795.7 TRUE FALSE FALSE 1942.254594 1787.946975 2143.915957 2007.55874 2094.127539 2418.188208 2720.753667 4069.968742 2232.611584 1858.100441 1.045290422 0.962244524 1.153821348 1.080436071 1.127026017 1.301430296 1.464266197 2.190392215 1.201555919 1 10.85961277 -1 0.663781972 1.023771534 115.5268431 0.951903724 0.075191316 18.65085918 0.106067706 0.008011385 3153.647043 0.1 1 114.5030716 up VSVGAPDLSLEASEGS(ph)IKLPK ddPTM_HeLa_Curcumin_4h_R1 2 VSVGAPDLSLEASEGSIKLPK 21 1 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 VSVGAPDLSLEAS(0.08)EGS(0.92)IKLPK;VSVGAPDLSLEAS(0.029)EGS(0.971)IKLPK ; 84.947 0.00037068 350560000 3024 2213.3 2573.35 2816.8 2734.6 5863 8074.9 3313.7 1977.95 2147.07 TRUE FALSE FALSE 2784.647209 2404.60779 2668.720615 2805.144828 2701.991681 4646.94771 8301.459962 4324.031876 1760.973834 2221.680523 1.253396778 1.082337341 1.201217091 1.262622956 1.216192721 2.091636337 3.736567826 1.946288781 0.792631441 1 11.11743566 -5.093648754 3.403075683 1.142196124 2.861618806 0.72382471 0.431097986 0.076602982 1.663978499 0.051792441 0.151070747 8.06E-06 5.093648754 1.719422682 VSVT(ph)PPEESQNSDT(ph)PPRPDR ddPTM_HeLa_Curcumin_4h_R1 1 VSVTPPEESQNSDTPPRPDR 20 1 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 2 0 VS(0.067)VT(0.909)PPEES(0.026)QNS(0.367)DT(0.631)PPRPDR 78.707 0.0018015 5269900 3192.4 2893.6 3023.8 3745.8 3619 4002.3 2920.5 2583.9 3881.3 3208.7 TRUE FALSE FALSE 2939.718171 3143.70989 3135.864688 3730.300872 3575.845789 3172.177865 3002.44137 3371.719215 3455.531101 3320.202086 0.885403387 0.946842936 0.944480067 1.123516212 1.076996428 0.955417105 0.904294766 1.015516263 1.04075927 1 11.69705534 -6.429241756 24.99544914 0.944487923 1.011596489 0.092063095 0.068800228 78.69472758 21002.10803 0.011226094 0.01714814 3.72E-07 6.429241756 0.067108565 VSVTPPEESQNSDT(ph)PPRPDR ddPTM_HeLa_Curcumin_4h_R1 1 VSVTPPEESQNSDTPPRPDR 20 1 Q05209-2;Q05209-3;Q05209;H3BM04 Q05209-2 PTPN12 Tyrosine-protein phosphatase non-receptor type 12 1 0 VSVTPPEES(0.014)QNS(0.431)DT(0.555)PPRPDR 66.201 0.0066405 16646000 518.4 589.9 485.02 664.6 703.43 563.67 784.91 409.89 473.05 525.31 TRUE FALSE FALSE 477.368093 640.8883275 502.9952679 661.8500613 695.0420567 446.7584881 806.9324621 534.8635741 421.1575985 543.5644834 0.878217962 1.179047467 0.925364484 1.217610939 1.278674523 0.821905223 1.484520212 0.983992866 0.774807059 1 9.086307383 -6.734261616 1.284144552 0.946657157 1.156760094 0.216563937 0.190929491 0.473826555 1.570798177 0.030690301 0.046570171 1.84E-07 6.734261616 0.210102936 VT(ph)KSPGETSKPR ddPTM_HeLa_Curcumin_4h_R1 1 VTKSPGETSKPR 12 2 F2Z2K0;Q9UNZ2-4;Q9UNZ2;Q9UNZ2-5;Q9UNZ2-6 F2Z2K0 NSFL1C NSFL1 cofactor p47 1 0 VT(0.999)KS(0.001)PGETSKPR 86.463 0.0080236 26182000 5339.8 5042.7 5581.4 4907.3 6010.9 6360.7 5124.9 5125 5545.8 5477.3 TRUE FALSE FALSE 4917.149195 5478.568518 5788.251594 4886.994893 5939.223943 5041.41912 5268.690901 6687.588907 4937.439615 5667.635767 0.867583839 0.966640896 1.021281506 0.862263401 1.04791913 0.889510076 0.929610003 1.179960954 0.871163889 1 12.46853133 -4.259509195 24.63975706 0.94259665 1.179961052 0.556862037 0.064286261 83.10596758 1060785.301 0.008952431 0.078062277 5.50E-05 4.259509195 0.237364401 VT(ph)LS(ph)S(ph)KPQALAT(ph)PNKEEHGK ddPTM_HeLa_Curcumin_4h_R1 1 VTLSSKPQALATPNKEEHGK 20 2 Q99075 Q99075 HBEGF Proheparin-binding EGF-like growth factor;Heparin-binding EGF-like growth factor 4 0 VT(1)LS(1)S(1)KPQALAT(1)PNKEEHGK 56.407 0.0075035 0 2025.9 1709.4 1392.8 1742.5 1332.8 659.71 935.11 820.48 1890.2 1612 TRUE FALSE FALSE 1865.547877 1857.152919 1444.418393 1735.289997 1316.90723 522.8787095 961.3466699 1070.640575 1682.849789 1668.01688 1.118422661 1.113389763 0.865949506 1.040331197 0.789504738 0.313473272 0.576341092 0.641864353 1.008892541 1 10.70391817 -5.552949441 3.462075147 1.044884307 0.516899669 0.826542674 0.104973399 0.066780369 1.677411714 0.015702757 0.034453802 2.80E-06 5.552949441 -0.527984638 VT(ph)NDISPESSPGVGR ddPTM_HeLa_Curcumin_4h_R1 1 VTNDISPESSPGVGR 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 0 VT(0.91)NDISPES(0.089)SPGVGR 166.79 0.00063445 5708900 1678.1 1385.3 1429.8 1463.3 1242.7 1515.4 978.02 718.84 1584.5 1436.2 TRUE FALSE FALSE 1545.276614 1505.039159 1482.789646 1457.245252 1227.881614 1201.088958 1005.460609 938.0110069 1410.684314 1486.107843 1.039814588 1.012738858 0.997767189 0.980578401 0.826239912 0.80821117 0.676573113 0.631186365 0.949247607 1 10.5373231 -5.196433039 0.87154094 1.020787137 0.601777757 0.943012168 0.03343615 0.098376402 0.112889163 0.004302335 0.028935412 6.36E-06 5.196433039 -0.41900938 VT(ph)PTKESYTEEIVSEAESHVSGISR ddPTM_HeLa_Curcumin_4h_R1 2 VTPTKESYTEEIVSEAESHVSGISR 25 1 E9PRB3;J3KP30;Q5QJE6 E9PRB3 DNTTIP2 Deoxynucleotidyltransferase terminal-interacting protein 2 1 0 VT(0.651)PT(0.214)KES(0.062)Y(0.052)T(0.021)EEIVSEAESHVSGISR;VT(0.921)PT(0.053)KES(0.018)Y(0.004)T(0.004)EEIVSEAESHVSGISR ; 97.352 3.12E-06 4001900 1627.93 1451.16 1200.02 1179.81 1762.62 3980.6 1824.96 719.99 1624.52 1383.13 TRUE FALSE FALSE 1499.077623 1576.591804 1244.493797 1174.928259 1741.601908 3154.978689 1876.163466 939.5116366 1446.31422 1431.193665 1.047431707 1.101592219 0.869549543 0.820942887 1.216887659 2.204438692 1.310908169 0.656453183 1.010564996 1 10.48300319 -5.522211365 24.99560899 1.004779915 1.437302859 0.211745037 0.357425606 25.84971643 968148.6467 0.050206906 0.101377533 3.00E-06 5.522211365 0.432522943 QPAQELS(ph)PTPGGTAHQALK ddPTM_HeLa_Curcumin_4h_R1 2 QPAQELSPTPGGTAHQALK 19 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 0 QPAQELS(0.816)PT(0.182)PGGT(0.002)AHQALK;QPAQELS(0.552)PT(0.346)PGGT(0.102)AHQALK ; 127.01 0.00013585 16515200 7570.4 6599.4 6691.9 6222.3 6114 7232.5 4730.4 2624.94 7528.4 7912.1 TRUE FALSE FALSE 6971.194852 7169.82273 6939.907701 6196.553771 6041.094543 5732.397973 4863.122293 3425.272122 6702.553355 8187.044886 0.851490977 0.875752219 0.847669434 0.756873067 0.737884625 0.700179131 0.594002153 0.418377103 0.818677978 1 12.99912709 -3.952775975 0.288728514 0.971697829 6.54E-20 0.861619045 0.05748956 1.744049608 0.094146284 0.021656126 0.617603617 0.000111487 3.952775975 -0.971697829 down VTADVINAAEK ddPTM_HeLa_Curcumin_4h_R1 1 VTADVINAAEK 11 0 A0A286YF22;A0A2C9F2M7;O43175;A0A286YFL2;A0A286YFA2;A0A286YFM8;A0A286YER3;A0A286YFC8;A0A286YFB2;A0A286YF34 A0A286YF22 PHGDH D-3-phosphoglycerate dehydrogenase 0 0 142.07 2.46E-05 2962900 1407.2 1113.2 1117.8 1503.9 1211 1778 1086.5 1271.1 1496.5 1453.8 FALSE FALSE TRUE 1295.818635 1209.420048 1159.226651 1497.67726 1196.559616 1409.222758 1116.984266 1658.652539 1332.337694 1504.319442 0.861398583 0.803964912 0.77059873 0.995584594 0.795415909 0.936784249 0.742518002 1.102593301 0.885674716 1 10.55489524 -9.111376901 0.942321856 0.997785807 0.86996354 0.013381791 0.110528444 0.693091832 1.138459653 0.05741 0.018034126 7.74E-10 9.111376901 -0.127822267 VTAEADSS(ph)SPTGILATSESK ddPTM_HeLa_Curcumin_4h_R1 1 VTAEADSSSPTGILATSESK 20 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 0 VTAEADSS(0.5)S(0.5)PTGILATSESK 352.64 3.65E-177 41816000 4513.6 3634.4 4164.9 4336.7 4899.9 6371.1 5254.3 4437.5 4362.1 3892.3 TRUE FALSE FALSE 4156.343797 3948.541341 4319.254858 4318.755884 4841.471893 5049.662043 5401.721517 5790.473322 3883.588543 4027.557135 1.031976371 0.980381211 1.072425471 1.072301581 1.202086458 1.253777879 1.341190537 1.437713514 0.964254116 1 11.97568934 -5.039934839 0.682864783 1.009573465 1.504777081 0.968511407 0.027633382 0.140113811 0.079701859 0.004224386 0.043922206 9.12E-06 5.039934839 0.495203617 VTAEADSSS(ph)PTGILATSESK ddPTM_HeLa_Curcumin_4h_R1 3 VTAEADSSSPTGILATSESK 20 0 A0MZ66-7;A0MZ66-8;A0MZ66-4;A0MZ66-5;A0MZ66-6;A0MZ66;A0MZ66-3 A0MZ66-7 KIAA1598 Shootin-1 1 0 VTAEADS(0.001)S(0.065)S(0.925)PT(0.009)GILATSESK;VTAEADSS(0.038)S(0.899)PT(0.056)GILAT(0.005)S(0.002)ESK;VTAEADS(0.004)S(0.032)S(0.856)PT(0.107)GILATSESK ;; 369.68 2.11E-201 52597300 6924.2 5225.5 5647 6150.8 6546.7 8144.6 7117.2 6895.6 6056.3 5352.9 TRUE FALSE FALSE 6376.142264 5677.168936 5856.282788 6125.349619 6468.634878 6455.318151 7316.889477 8998.036697 5391.939042 5538.912877 1.151154099 1.024960865 1.057298231 1.105875784 1.167852794 1.165448581 1.320997394 1.62451313 0.97346522 1 12.43538713 -1 0.621004598 1.06661256 42.42679369 0.923276589 0.050618948 37.22558582 0.247006605 0.01011086 2107.084148 0.1 1 41.36018113 VTAQGPGLEPSGNIANK ddPTM_HeLa_Curcumin_4h_R1 2 VTAQGPGLEPSGNIANK 17 0 P21333-2;P21333;F8WE98;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 332.7 2.80E-178 6074400 2396.8 1775.08 2477.3 1935.47 2652.5 3026.4 2257.2 2786.7 1788.47 1946.29 FALSE FALSE TRUE 2207.090751 1928.510006 2569.110917 1927.461538 2620.87067 2398.690525 2320.530957 3636.352002 1592.279316 2013.923433 1.09591592 0.957588543 1.275674574 0.957067934 1.301375528 1.191053486 1.152243883 1.805605885 0.790635478 1 10.97579312 -1.263328544 0.894125461 1.062721334 199.9999998 0.689775286 0.147252783 169.1029651 0.621247075 0.017462929 68281.12866 0.054534515 1.263328544 198.9372785 VTAYK(ac)AVQEK ddPTM_HeLa_Curcumin_4h_R1 1 VTAYKAVQEK 10 1 Q9Y2W1;A0A3B3ITZ9 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 0 1 VTAYK(1)AVQEK 121.08 0.0027305 1845000 1119.2 647.77 1113 979.47 1043.1 1638.8 1526.5 1331 842.74 959.9 FALSE TRUE FALSE 1030.614139 703.7603524 1154.248759 975.4172127 1030.661714 1298.894407 1569.329482 1736.815773 750.2935304 993.2564536 1.037611319 0.708538414 1.162085336 0.982039643 1.037659217 1.30771303 1.579984178 1.748607589 0.755387521 1 9.956022452 -4.857912506 1.490717242 0.99978065 1.769985558 0.823996061 0.132104979 0.120484115 0.452458208 0.015035907 0.098389081 1.39E-05 4.857912506 0.770204907 VTDALNATR ddPTM_HeLa_Curcumin_4h_R1 2 VTDALNATR 9 0 P10809 P10809 HSPD1 "60 kDa heat shock protein, mitochondrial" 0 0 ; ; 157.99 3.96E-08 25521000 10541.3 7829.8 9461.7 9650 11113.9 16031.2 10895.8 10272.3 10589.3 7841.6 FALSE FALSE TRUE 9706.944982 8506.573023 9812.358925 9610.070857 10981.374 12706.14841 11201.50682 13404.27698 9427.680283 8114.095016 1.196306546 1.048369905 1.209298006 1.184367553 1.353370151 1.565935374 1.380499834 1.651974367 1.161889313 1 12.98621448 -1 0.207053124 1.007767314 4.145195232 0.792639027 0.091361222 14.69810159 0.171356685 0.076005744 15.24673695 0.1 1 3.137427917 VTDALPEPEPPGAMAAS(ph)EDEEEEEEALEAMQSR ddPTM_HeLa_Curcumin_4h_R1 3 VTDALPEPEPPGAMAASEDEEEEEEALEAMQSR 33 0 Q9Y3E7-2;Q9Y3E7-4;Q9Y3E7;Q9Y3E7-3 Q9Y3E7-2 CHMP3 Charged multivesicular body protein 3 1 0 VTDALPEPEPPGAMAAS(1)EDEEEEEEALEAMQSR;VTDALPEPEPPGAMAAS(1)EDEEEEEEALEAMQSR;VTDALPEPEPPGAMAAS(1)EDEEEEEEALEAMQSR ;; 132.7 3.54E-18 13931900 10884.8 8435.9 8242.78 10211.4 8791.6 11416.2 8842.3 8229.1 11276.1 8406.9 TRUE FALSE FALSE 10023.25659 9165.061606 8548.264678 10169.14793 8686.765912 9048.351433 9090.39114 10738.11471 10039.14004 8699.039149 1.152225714 1.053571716 0.982667687 1.168996685 0.998589127 1.040155272 1.044987956 1.234402389 1.154051599 1 13.08664034 -9.657171478 1.511098413 1.000163034 1.088825395 0 0.088898378 0.600236962 2.472841016 0.052711609 0.011962608 2.20E-10 9.657171478 0.08866236 VTDMADYTYST(ph)VPRR ddPTM_HeLa_Curcumin_4h_R1 1 VTDMADYTYSTVPRR 15 1 A0A1B0GW36;Q9H0J4-3;Q9H0J4 A0A1B0GW36 QRICH2 Glutamine-rich protein 2 1 0 VTDMADY(0.028)T(0.236)Y(0.066)S(0.104)T(0.565)VPRR 95.483 0.0029014 26218000 1924.3 985.06 1363.7 1194.4 1823.8 2651.1 1280.2 1769.1 1614.3 1414.9 TRUE FALSE FALSE 1771.989624 1070.204197 1414.239922 1189.457889 1802.052376 2101.231976 1316.118967 2308.490446 1437.215329 1464.06767 1.210319483 0.730980008 0.965966226 0.812433683 1.2308532 1.435201405 0.898946814 1.576764854 0.981659085 1 10.51576652 -5.548409821 24.87734951 1.041082434 1.274811795 0.331912606 0.211215826 244.9141481 238642.3808 0.030766726 0.061535123 2.83E-06 5.548409821 0.233729361 VTEAEIVPMGK ddPTM_HeLa_Curcumin_4h_R1 1 VTEAEIVPMGK 11 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;H7C5L4 O75369-8 FLNB Filamin-B 0 0 104.05 0.0065459 1919400 2383.9 2027.1 2243.3 2296.6 1965.3 3326.7 2428.6 2425.7 2212.3 1910.3 FALSE FALSE TRUE 2195.2118 2202.313491 2326.438671 2287.097278 1941.865081 2636.70492 2496.73998 3165.284763 1969.616225 1976.682783 1.110553407 1.114146139 1.176940828 1.157038093 0.982385792 1.333903924 1.263095931 1.601311445 0.996425042 1 10.94886565 -1 0.481652908 1.057224006 15.73293201 0.787688991 0.08275061 27.94352248 0.280846411 0.016485677 413.835383 0.1 1 14.67570801 VTEGLVDVILYHQPDDK ddPTM_HeLa_Curcumin_4h_R1 1 VTEGLVDVILYHQPDDK 17 0 O43390;B4DT28;O43390-3 O43390 HNRNPR Heterogeneous nuclear ribonucleoprotein R 0 0 137.27 0.00028182 13284000 3910.4 3189.5 3771.9 3946.5 4099 4926.6 4103.3 3624.6 4206.8 3458.4 FALSE FALSE TRUE 3600.887714 3465.186168 3911.689932 3930.170429 4050.122102 3904.767626 4218.427555 4729.723854 3745.324565 3578.579143 1.006233919 0.968313409 1.093084651 1.09824885 1.131768208 1.091150278 1.17879957 1.321676472 1.046595427 1 11.80517117 -1 0.329975819 0.994918391 4.225770047 0.842105645 0.038742521 12.09689755 0.15355869 0.011534008 24.16296106 0.1 1 3.230851656 VTEGSFVYK ddPTM_HeLa_Curcumin_4h_R1 2 VTEGSFVYK 9 0 V9GYJ7;V9GYF8;Q5SX90;Q5SX86;Q5SX87;P50395 V9GYJ7 GDI2 Rab GDP dissociation inhibitor beta 0 0 ; ; 120.15 0.0013409 10727800 4169 3070.1 2900.7 3727 3849.2 4171.7 3595.3 3221.8 3577.8 3485.5 FALSE FALSE TRUE 3839.019251 3335.465764 3008.202494 3711.578662 3803.300804 3306.442395 3696.174442 4204.111989 3185.324291 3606.620866 1.0644366 0.924817409 0.834077827 1.029101422 1.054533023 0.916770162 1.024830327 1.165665077 0.883188006 1 11.81643206 -4.278341239 4.53647515 1.004046709 1.17408873 0.275170304 0.080199192 0.179539455 9.227556805 0.010597526 0.093744306 5.27E-05 4.278341239 0.170042021 VTENLASLT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 VTENLASLTPK 11 0 Q96DF8 Q96DF8 DGCR14 Protein DGCR14 1 0 VTENLASLT(1)PK 149.82 6.25E-05 0 3667.9 2831.2 2820.1 3414.7 3169.3 3912.2 2955.5 1953.9 3472.4 2771.3 TRUE FALSE FALSE 3377.581845 3075.916312 2924.615387 3400.570876 3131.508167 3100.76562 3038.423376 2549.635115 3091.486408 2867.602469 1.177841727 1.072643906 1.019881737 1.18585854 1.092030085 1.08130944 1.059569243 0.889117353 1.078073562 1 11.48562932 -4.233299986 2.72711284 1.087909724 0.842690901 0.53726127 0.055174389 0.400975755 3.728468301 0.010082215 0.227159347 5.84E-05 4.233299986 -0.245218823 VTFFEPGS(ph)GDENGTSNKEDEFR ddPTM_HeLa_Curcumin_4h_R1 2 VTFFEPGSGDENGTSNKEDEFR 22 1 Q5JW30;O95793-2;O95793-3;O95793 Q5JW30 STAU1 Double-stranded RNA-binding protein Staufen homolog 1 1 0 VTFFEPGS(0.997)GDENGT(0.002)S(0.001)NKEDEFR;VT(0.002)FFEPGS(0.988)GDENGT(0.01)S(0.001)NKEDEFR ; 68.088 0.0012225 12160000 2317.49 1760.46 2295.41 2416.1 2361.5 2760.08 2380.55 1654.03 2290.15 2133.99 TRUE FALSE FALSE 2134.058221 1912.626318 2380.479914 2406.102818 2333.340655 2187.608295 2447.341826 2158.336133 2038.926275 2208.145994 0.966447974 0.866168416 1.078044622 1.089648431 1.056696732 0.990699121 1.108324283 0.977442678 0.923365702 1 11.10861985 VTFGEDLS(ph)PEVFDESLPANTPLRK ddPTM_HeLa_Curcumin_4h_R1 2 VTFGEDLSPEVFDESLPANTPLRK 24 1 E9PEI0;Q69YH5 E9PEI0 CDCA2 Cell division cycle-associated protein 2 1 0 VT(0.033)FGEDLS(0.967)PEVFDESLPANTPLRK;VT(0.013)FGEDLS(0.987)PEVFDESLPANTPLRK ; 81.151 0.00010926 48538000 2410.81 2179.35 2012.25 2518.5 2283.6 2649.5 1767.57 1277.79 2925.2 2161.19 TRUE FALSE FALSE 2219.991845 2367.723303 2086.825755 2508.079114 2256.369561 2099.963834 1817.163257 1667.382289 2604.312878 2236.291192 0.992711438 1.05877236 0.933163697 1.121535122 1.008978424 0.939038638 0.812578999 0.745601599 1.164567874 1 11.12689234 -4.766428727 2.120474673 1.006515904 0.749465708 0.684165312 0.068483398 0.104492275 0.877516985 0.00633622 0.03465833 1.71E-05 4.766428727 -0.257050195 VTFLIGDSMS(ph)PDSDTELR ddPTM_HeLa_Curcumin_4h_R1 3 VTFLIGDSMSPDSDTELR 18 0 A0A087WX11;J3KNG8;Q8TF40-3;Q8TF40 A0A087WX11 FNIP1 Folliculin-interacting protein 1 1 0 VTFLIGDS(0.067)MS(0.932)PDSDTELR;VTFLIGDS(0.166)MS(0.824)PDS(0.009)DT(0.001)ELR;VTFLIGDS(0.279)MS(0.714)PDS(0.006)DT(0.001)ELR ;; 115.58 0.00054519 19095600 8552.3 7103.07 7133.8 7125 7096.5 7861.9 4426.65 5696.32 7971.05 7524.3 TRUE FALSE FALSE 7875.376431 7717.02772 7398.184904 7095.518638 7011.878872 6231.253318 4550.849885 7433.101745 7096.645758 7785.768865 1.011509148 0.991170924 0.950218923 0.911344629 0.900601982 0.800338852 0.584508732 0.954703623 0.911489396 1 12.9266238 -5.697441556 1.125779223 1.002991136 0.757362261 0.428373633 0.091343714 0.249145415 0.612274874 0.012794498 0.03907313 2.01E-06 5.697441556 -0.245628875 RKS(ph)PGVAAAVAEDGGLKK ddPTM_HeLa_Curcumin_4h_R1 1 RKSPGVAAAVAEDGGLKK 18 3 E9PLH8;E9PM78;H0YD80;E9PLS2;E9PQV9;E9PM04;Q9BTE7 E9PLH8 DCUN1D5 DCN1-like protein;DCN1-like protein 5 1 0 RKS(1)PGVAAAVAEDGGLKK 60.949 0.012992 27543000 2976.7 2444 2578.4 2858.1 2388.9 3321.1 2177.2 1057.1 3448.7 2790 TRUE FALSE FALSE 2741.091054 2655.24847 2673.957772 2846.273939 2360.413928 2632.266423 2238.286372 1379.404924 3070.386238 2886.952292 0.949475702 0.919741028 0.92622167 0.985909586 0.817614456 0.911780368 0.775311174 0.477806622 1.06353896 1 11.49533155 -3.952275329 0.898182724 0.96442179 2.05E-14 0.869058356 0.056685145 0.743971838 0.308917883 0.007607609 0.799881853 0.000111616 3.952275329 -0.96442179 down VTGGAASK(ac)LSK ddPTM_HeLa_Curcumin_4h_R1 1 VTGGAASKLSK 11 1 F2Z388;P42766 F2Z388 RPL35 60S ribosomal protein L35 0 1 VTGGAASK(1)LSK 178.67 1.41E-11 37865000 2944 2183.3 2554.4 2472 2657.1 3554.5 2885 2074.5 2842.8 2536.3 FALSE TRUE FALSE 2710.979294 2372.014723 2649.068311 2461.771519 2625.415818 2817.256633 2965.945335 2707.0055 2530.951952 2624.436236 1.032975866 0.903818767 1.009385663 0.938019177 1.000373254 1.073471168 1.130126651 1.031461715 0.964379289 1 11.35779183 -5.232921625 5.146340373 0.999914866 1.084780386 0.463800295 0.045229473 0.145456611 10.9273731 0.006418909 0.016331031 5.85E-06 5.232921625 0.08486552 LSEGPAAMAGPGS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 1 LSEGPAAMAGPGSPPR 16 0 Q8N2Y8 Q8N2Y8 RUSC2 Iporin 1 0 LS(0.004)EGPAAMAGPGS(0.996)PPR 111.81 0.0017387 17372000 4166.6 2920.2 3260.8 3365.7 3291.6 3903.8 2644 1215.6 4117.2 3652.6 TRUE FALSE FALSE 3836.809213 3172.609076 3381.648116 3351.773625 3252.34982 3094.107875 2718.183524 1586.230844 3665.553461 3779.527578 1.015155766 0.83941948 0.894727726 0.886823434 0.860517552 0.818649371 0.719186054 0.419690242 0.969844348 1 11.8839902 -3.941700249 0.483414807 0.997785186 1.48E-24 0.862310385 0.06101771 1.41649941 0.178863119 0.013576275 0.858185832 0.000114367 3.941700249 -0.997785186 down VTGS(ph)LSSAK ddPTM_HeLa_Curcumin_4h_R1 2 VTGSLSSAK 9 0 P39748-2;P39748 P39748-2 FEN1 Flap endonuclease 1 1 0 VT(0.048)GS(0.641)LS(0.286)S(0.025)AK;VT(0.06)GS(0.93)LS(0.005)S(0.005)AK ; 140.78 0.0023335 16836500 6504.5 4388.5 5136.1 5451 5549.5 8009.7 7133.5 4286.6 5820.4 5054.3 TRUE FALSE FALSE 5989.661961 4767.822385 5326.448384 5428.445206 5483.325837 6348.397932 7333.646811 5593.564607 5181.916682 5229.936549 1.145264748 0.911640579 1.01845373 1.037956227 1.048449782 1.213857544 1.402243936 1.069528197 0.99081827 1 12.35257773 -5.213811002 4.632909703 1.050426758 1.250539885 0.476350127 0.095791397 0.145804027 7.053372756 0.013686094 0.035633786 6.11E-06 5.213811002 0.200113128 VTGTEGSS(ph)STLVDYTSTSSTGGSPVR ddPTM_HeLa_Curcumin_4h_R1 1 VTGTEGSSSTLVDYTSTSSTGGSPVR 26 0 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 0 VT(0.001)GT(0.002)EGS(0.05)S(0.709)S(0.04)T(0.01)LVDY(0.001)T(0.003)S(0.002)T(0.019)S(0.047)S(0.08)T(0.007)GGS(0.029)PVR 90.06 8.47E-06 15833000 1112 1056.4 1482.8 1361.4 1318.1 1292.9 1333.4 904.78 1110.3 1230.8 TRUE FALSE FALSE 1023.984027 1147.710509 1537.753872 1355.766888 1302.382518 1024.737966 1370.811615 1180.643257 988.5028678 1273.570208 0.804026366 0.901175688 1.207435493 1.06454036 1.02262326 0.804618355 1.076353393 0.927034292 0.776166764 1 10.31466278 VTGTEGSSSTLVDYTSTS(ph)STGGSPVRK ddPTM_HeLa_Curcumin_4h_R1 2 VTGTEGSSSTLVDYTSTSSTGGSPVRK 27 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 0 VTGTEGSSSTLVDYTS(0.005)T(0.048)S(0.397)S(0.26)T(0.26)GGS(0.03)PVRK;VTGTEGSSSTLVDY(0.008)T(0.007)S(0.022)T(0.049)S(0.281)S(0.281)T(0.281)GGS(0.071)PVRK ; 105.25 5.43E-08 173819000 3370.5 2875.7 3289.9 3136.5 3066.6 3752.1 2645 2812.5 3511.6 3198.7 TRUE FALSE FALSE 3103.721368 3124.262694 3411.826588 3123.521994 3030.032798 2973.872165 2719.211581 3670.018303 3126.386266 3309.854587 0.937721367 0.943927478 1.030808605 0.943703692 0.915457981 0.898490277 0.821550165 1.108815571 0.944569069 1 11.69255212 -6.008610842 23.34065177 0.972209405 0.925758989 0.045262913 0.072234582 331.4595095 898469.0313 0.010085584 0.017628814 9.80E-07 6.008610842 -0.046450416 VTKNEEPS(ph)EEEIDAPKPK ddPTM_HeLa_Curcumin_4h_R1 5 VTKNEEPSEEEIDAPKPK 18 2 Q9NR30;Q9NR30-2 Q9NR30 DDX21 Nucleolar RNA helicase 2 1 0 VT(0.002)KNEEPS(0.998)EEEIDAPKPK;VT(0.001)KNEEPS(0.999)EEEIDAPKPK;VT(0.002)KNEEPS(0.998)EEEIDAPKPK;VT(0.001)KNEEPS(0.999)EEEIDAPKPK;VT(0.019)KNEEPS(0.981)EEEIDAPKPK ;;;; 115.31 0.0003421 1029304000 27334.4 21476 23804.4 28338.1 23486.1 28920.7 24581.3 18706 30820.7 24624.9 TRUE FALSE FALSE 25170.8534 23332.28974 24686.612 28220.84445 23206.0436 22922.22082 25270.98512 24409.37329 27439.74632 25480.61344 0.987843305 0.915687913 0.968838998 1.107541799 0.910733317 0.899594543 0.991773027 0.95795862 1.076887194 1 14.63711239 -5.572425817 0.152836993 1.014324167 0.919971842 0.127722222 0.060696561 30.41540448 1.401779572 0.21894575 0.680595388 2.68E-06 5.572425817 -0.094352325 VTLLEGDHVR ddPTM_HeLa_Curcumin_4h_R1 2 VTLLEGDHVR 10 0 O75534-2;O75534;O75534-3;O75534-4;E9PLT0 O75534-2 CSDE1 Cold shock domain-containing protein E1 0 0 ; ; 175.65 8.48E-15 3606600 7488.8 5304.6 6653.5 6094 7409.3 7613.5 6439.3 6106.6 6523.6 5963.5 FALSE FALSE TRUE 6896.053578 5763.105987 6900.084563 6068.784643 7320.948937 6034.374278 6619.969428 7968.474229 5807.977401 6170.731181 1.117542375 0.933942157 1.118195617 0.983479018 1.186398941 0.977902634 1.072801461 1.291333878 0.941213809 1 12.59122573 -4.26854111 4.693151177 1.051661691 1.304282881 0.462970841 0.08110793 0.111160867 6.663275348 0.009748421 0.090859412 5.39E-05 4.26854111 0.25262119 VTLQDYRLPDS(ph)DDDEDEETAIQR ddPTM_HeLa_Curcumin_4h_R1 1 VTLQDYRLPDSDDDEDEETAIQR 23 1 H3BRF9;Q96K21-2;Q96K21;Q96K21-4 H3BRF9 ZFYVE19 Abscission/NoCut checkpoint regulator 1 0 VTLQDY(0.003)RLPDS(0.997)DDDEDEETAIQR 79.942 0.00024245 2884000 1123.7 697.05 705.19 794.55 327.5 1109.6 730.23 676.22 1841.9 1094.6 TRUE FALSE FALSE 1034.757959 757.299896 731.3249617 791.2623626 323.5947764 879.4564522 750.7182885 882.3963651 1639.848178 1132.637269 0.913582828 0.668616438 0.645683293 0.698601737 0.285700273 0.776467874 0.662805568 0.779063509 1.447814074 1 10.14547019 -7.296649152 2.170040111 0.966977349 0.63293938 0.502328894 0.200374862 0.160442763 1.429765529 0.023368791 0.02734261 5.05E-08 7.296649152 -0.334037969 VTLTSEEEAR ddPTM_HeLa_Curcumin_4h_R1 2 VTLTSEEEAR 10 0 P00338;P00338-3;P00338-4 P00338 LDHA L-lactate dehydrogenase A chain 0 0 ; ; 152.11 1.16E-06 116944000 6245.1 5360.2 5934.6 6439.1 7756.7 9342 6159.9 5793.4 8737.1 5856.9 FALSE FALSE TRUE 5750.793745 5823.511803 6154.541497 6412.45671 7664.206419 7404.363894 6332.730215 7559.78099 7778.661989 6060.426839 0.948909029 0.960907863 1.015529378 1.058086646 1.264631456 1.221756172 1.044931386 1.247400751 1.283517184 1 12.56520369 -6.020669704 3.095891559 0.976832818 1.185450964 0.194877627 0.113932273 0.098353969 1.923049368 0.008984335 0.01635314 9.54E-07 6.020669704 0.208618146 VTLVFEHVDQDLR ddPTM_HeLa_Curcumin_4h_R1 2 VTLVFEHVDQDLR 13 0 F8W1L8;F8VXD2;F8VYH9;F8VZZ0;F8VTV8;F8VWX7;F8VZ51;P11802 F8W1L8 CDK4 Cyclin-dependent kinase 4 0 0 ; ; 156 0.00029587 24432000 11781.2 10599.8 10558.1 10681 9724.5 11453.7 9803.4 9924.2 11271.9 10777.4 FALSE FALSE TRUE 10848.70559 11515.99948 10949.39247 10636.80485 9608.541689 9078.07351 10078.45702 12950.04289 10035.40077 11151.91385 0.972811101 1.032647816 0.981839765 0.953809812 0.861604727 0.814037271 0.903742367 1.161239503 0.899881483 1 13.4450037 -6.118828962 3.791086297 0.990548753 0.922918266 0.027295312 0.091348229 0.407799758 10.43447665 0.012951617 0.022244348 7.61E-07 6.118828962 -0.067630487 VTLYNTDQDGSDS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 VTLYNTDQDGSDSPR 15 0 C9JXI1;C9JVP0;Q9UPW0-2;Q9UPW0 C9JXI1 FOXJ3 Forkhead box protein J3 1 0 VTLYNTDQDGS(0.001)DS(0.999)PR 197.51 8.35E-07 12463000 2471.7 2174.9 1960.6 2535.8 1936.4 1516 1306.4 1003.7 2533.4 1804.8 TRUE FALSE FALSE 2276.062337 2362.888665 2033.261561 2525.307531 1913.309695 1201.564511 1343.054068 1309.72351 2255.492358 1867.516666 1.218764137 1.26525707 1.088751494 1.352227575 1.024520814 0.643402296 0.719165774 0.701318244 1.207749521 1 10.8669054 -5.364512578 4.316205383 1.135113067 0.691678935 0.824206433 0.101346461 0.085760934 2.712037026 0.017205979 0.040055084 4.32E-06 5.364512578 -0.443434132 DQS(ph)LALSPK ddPTM_HeLa_Curcumin_4h_R1 1 DQSLALSPK 9 0 E7EX48;P51957-3;P51957;H7C5M0 E7EX48 NEK4 Serine/threonine-protein kinase Nek4 1 0 DQS(0.873)LALS(0.127)PK 89.663 0.019874 17473000 4857.9 4243.7 5196.7 4955.2 5043.8 4725.4 3957.4 1892.9 4891.9 4830 TRUE FALSE FALSE 4473.392089 4610.506518 5389.294273 4934.696695 4983.655979 3745.298774 4068.433993 2470.036496 4355.270809 4997.84214 0.895064703 0.922499429 1.078324229 0.987365458 0.997161543 0.749383167 0.814038115 0.494220591 0.871430247 1 12.28708962 -3.939478342 0.914438249 0.961358767 6.50E-10 0.778873917 0.074547831 1.163746755 0.492406012 0.0115015 1.276778632 0.000114953 3.939478342 -0.961358766 down ELPDSS(ph)SPVPANNIR ddPTM_HeLa_Curcumin_4h_R1 2 ELPDSSSPVPANNIR 15 0 A0A0C4DH56;Q9BWT3-2;Q9BWT3 A0A0C4DH56 PAPOLG Poly(A) polymerase gamma 1 0 ELPDS(0.002)S(0.499)S(0.499)PVPANNIR;ELPDS(0.001)S(0.5)S(0.5)PVPANNIR ; 112.62 0.001953 40502000 9982.4 8785.2 9018 9505.8 8281.3 10404.5 7957.6 3537.3 10145.6 8974.9 TRUE FALSE FALSE 9192.282507 9544.553542 9352.215013 9466.467518 8182.550906 8246.489417 8180.868839 4615.806486 9032.653063 9286.777107 0.989824823 1.027757362 1.007046353 1.01934906 0.881096942 0.887981839 0.880915817 0.497029963 0.972635927 1 13.18096229 -3.934357938 1.027406243 0.994622532 1.96E-29 0.907702006 0.045666235 0.639779394 0.336601487 0.006618581 0.81724783 0.000116317 3.934357938 -0.994622532 down VTNDISPES(ph)SPGVGR ddPTM_HeLa_Curcumin_4h_R1 4 VTNDISPESSPGVGR 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 0 VT(0.05)NDIS(0.099)PES(0.811)S(0.04)PGVGR;VT(0.416)NDIS(0.027)PES(0.556)S(0.001)PGVGR;VT(0.023)NDIS(0.09)PES(0.882)S(0.005)PGVGR;VT(0.36)NDIS(0.061)PES(0.576)S(0.003)PGVGR ;;; 173.19 0.00012758 599683000 10123.1 8137.6 9088.6 8907.8 8592.4 8181.9 4935.54 4387.61 10476 8910.3 TRUE FALSE FALSE 9321.845953 8840.977884 9425.431511 8870.941884 8489.941242 6484.881711 5074.017969 5725.372091 9326.80901 9219.932262 1.011053627 0.958898355 1.022288586 0.962148271 0.920824687 0.703354594 0.550331372 0.620977674 1.011591923 1 13.17054044 -5.223574196 1.880366466 1.000760153 0.578943988 0.975324443 0.026778497 0.031810853 0.213666055 0.003602319 0.012110555 5.98E-06 5.223574196 -0.421816166 VTPDIEES(ph)LLEPENEK ddPTM_HeLa_Curcumin_4h_R1 2 VTPDIEESLLEPENEK 16 0 Q14151 Q14151 SAFB2 Scaffold attachment factor B2 1 0 VTPDIEES(1)LLEPENEK;VTPDIEES(1)LLEPENEK ; 148.56 0.00035669 18837400 2419.28 2944.62 2783.74 3222.3 2665.92 4903.7 5899.2 3165.27 2591.02 3227.1 TRUE FALSE FALSE 2227.791435 3199.139832 2886.907853 3208.966976 2634.130645 3886.617344 6064.715675 4130.346252 2306.791588 3339.241485 0.667154935 0.958043869 0.864540006 0.960986796 0.788841016 1.163922215 1.816195595 1.236911517 0.690813048 1 11.70530471 -4.99798257 4.689535388 0.858416137 1.527827419 0.724319378 0.167655765 0.06970466 4.13184817 0.023910187 0.070922478 1.00E-05 4.99798257 0.669411282 VTPDIEESLLEPENEK ddPTM_HeLa_Curcumin_4h_R1 1 VTPDIEESLLEPENEK 16 0 Q14151 Q14151 SAFB2 Scaffold attachment factor B2 0 0 111.72 0.0034114 0 452.07 530.32 379.97 452.83 368.63 491.79 285.76 293.11 485.24 352.12 FALSE FALSE TRUE 416.2881825 576.1584977 394.0520225 450.9563094 364.234328 389.7872104 293.7776565 382.4778897 432.010386 364.3561438 1.142530981 1.581305839 1.081502341 1.237679993 0.999665668 1.069797277 0.806292584 1.049736353 1.185681629 1 8.509205507 -4.934075963 6.520316277 1.115677289 0.927449075 0.197072985 0.171776643 0.29361914 22.57713198 0.025017016 0.076284977 1.16E-05 4.934075963 -0.188228214 VTPRPQQTSASS(ph)PSSVNSR ddPTM_HeLa_Curcumin_4h_R1 1 VTPRPQQTSASSPSSVNSR 19 1 Q9ULD2-2;Q9ULD2;H0YC63;Q9ULD2-5 Q9ULD2-2 MTUS1 Microtubule-associated tumor suppressor 1 1 0 VTPRPQQTS(0.002)AS(0.093)S(0.621)PS(0.069)S(0.162)VNS(0.053)R 57.768 0.011508 5326300 741.63 619.93 682.86 689.39 765.73 611.04 532.16 330.62 626.14 586 TRUE FALSE FALSE 682.9292029 673.5139868 708.1673923 686.5374868 756.5991699 484.3034162 547.0909774 431.424516 557.4540085 606.3634564 1.126270384 1.110743037 1.167892598 1.132221079 1.247765118 0.798701523 0.902249256 0.711494915 0.919339717 1 9.244038999 -5.241217868 24.66265738 1.089607483 0.813958579 0.670115844 0.09502455 313.910903 382852.682 0.012610015 0.032104379 5.74E-06 5.241217868 -0.275648904 VTPTEEHVEGPLPSPVTNGT(ph)SPAQLNGGSACSSR ddPTM_HeLa_Curcumin_4h_R1 1 VTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSR 34 0 H3BN50;H3BQS0;Q15599-3;Q15599;H3BUQ9;Q15599-2 H3BN50;Q15599-2 SLC9A3R2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 1 0 VTPTEEHVEGPLPS(0.12)PVT(0.12)NGT(0.342)S(0.342)PAQLNGGS(0.072)ACS(0.002)S(0.002)R 83.601 8.68E-08 15520000 1262.2 1014.5 1086.2 1128.5 1376.9 1655.9 728.7 453.03 1490.5 931.95 TRUE FALSE FALSE 1162.295538 1102.188859 1126.455528 1123.830566 1360.481367 1312.447674 749.1453608 591.1567615 1326.995879 964.3351931 1.205281676 1.142952023 1.168116165 1.165394122 1.410797176 1.360987013 0.776851624 0.613020001 1.376073266 1 9.91339089 -4.607835327 5.715057582 1.148129478 0.651622285 0.680210184 0.139614104 0.089080932 4.516137539 0.02031296 0.079675892 2.47E-05 4.607835327 -0.496507192 ATFSGS(ph)AGR ddPTM_HeLa_Curcumin_4h_R1 4 ATFSGSAGR 9 0 Q9Y4H2 Q9Y4H2 IRS2 Insulin receptor substrate 2 1 0 ATFS(0.001)GS(0.999)AGR;ATFSGS(1)AGR;ATFSGS(1)AGR;ATFS(0.006)GS(0.994)AGR ;;; 133.75 0.0033291 154873000 12789 10469.4 10367.9 10092.8 10285 12393.9 9260.3 3639.48 12888.1 11285 TRUE FALSE FALSE 11776.73716 11374.32829 10752.14349 10051.03867 10162.35809 9823.265432 9520.119095 4749.140698 11474.30767 11677.15291 1.008528127 0.974066913 0.920784679 0.860743945 0.870277042 0.841238058 0.81527742 0.406703649 0.982628879 1 13.51140094 -3.932157911 0.609973953 0.994421904 1.27E-33 0.859623187 0.062772018 1.197516107 0.230944914 0.011183597 0.912689132 0.000116907 3.932157911 -0.994421904 down VTQSDLYK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 VTQSDLYKK 9 1 O43399;O43399-5;O43399-7;A0A087WYR3 O43399 TPD52L2 Tumor protein D54 0 1 VTQSDLYK(1)K 119.22 0.00047581 2474100 1128.7 1214.6 1131.4 1142.5 1410.8 1811.1 1875.2 1256.9 1796.2 935.27 FALSE TRUE FALSE 1039.362204 1319.584612 1173.330679 1137.772638 1393.977131 1435.457445 1927.813065 1640.123024 1599.161354 967.7705629 1.073975841 1.36353043 1.212405837 1.175663614 1.440400426 1.483262149 1.992014574 1.694743658 1.652417851 1 9.918521247 -4.790885807 0.402026713 1.011098991 2.283224525 0.325178513 0.241182805 1.012321311 0.148558825 0.036852205 0.574854137 1.62E-05 4.790885807 1.272125534 VTQVDGNS(ph)PVR ddPTM_HeLa_Curcumin_4h_R1 4 VTQVDGNSPVR 11 0 B0YIW6;P48444;P48444-2 B0YIW6 ARCN1 Coatomer subunit delta 1 0 VTQVDGNS(1)PVR;VTQVDGNS(1)PVR;VTQVDGNS(1)PVR;VTQVDGNS(1)PVR ;;; 129.17 0.0015444 50748000 6188.6 5761 6488.8 5925 6525.8 7285.1 6122.5 6111 6319.2 5119.4 TRUE FALSE FALSE 5698.76578 6258.955169 6729.280636 5900.48392 6447.984097 5774.08814 6294.280872 7974.215768 5625.99957 5297.298769 1.075787119 1.181537127 1.270323032 1.113866553 1.21722115 1.090006132 1.188205753 1.505336232 1.062050644 1 12.37104116 -1 0.15196167 0.960689991 2.364921978 0.505545116 0.095431665 37.83062489 0.370143266 0.198564724 11.79684607 0.1 1 1.404231986 VTS(ph)GGVSESPSGFSK ddPTM_HeLa_Curcumin_4h_R1 1 VTSGGVSESPSGFSK 15 0 E7EPP6;O14757-2;O14757-3;O14757 E7EPP6 CHEK1 Serine/threonine-protein kinase Chk1 1 0 VT(0.013)S(0.935)GGVS(0.046)ES(0.003)PS(0.002)GFSK 92.269 0.0066115 13728000 2701.1 2507.3 2581.8 2615.6 2748.7 3617.7 2290.7 2120 3422.5 3130.8 TRUE FALSE FALSE 2487.305085 2724.01984 2677.483779 2604.77734 2715.923548 2867.34824 2354.970877 2766.378241 3047.060313 3239.595067 0.767782712 0.840851953 0.826487176 0.804044112 0.838352785 0.885094643 0.726933715 0.853927168 0.940568265 1 11.66159778 -9.371292433 0.987772505 1.004916126 0.814691164 0.632843963 0.045631835 0.233626885 0.390817567 0.032599664 0.007601078 4.25E-10 9.371292433 -0.190224963 GLLSGQT(ph)SPTNAK ddPTM_HeLa_Curcumin_4h_R1 1 GLLSGQTSPTNAK 13 0 G3V1P3;Q969J3 G3V1P3 LOH12CR1 Loss of heterozygosity 12 chromosomal region 1 protein 1 0 GLLSGQT(0.333)S(0.333)PT(0.333)NAK 113.52 0.0095507 29966000 2648.3 2265.3 2459.4 2330.2 2959 3320.6 2851.8 3467.3 2463.7 1983.9 TRUE FALSE FALSE 2438.684261 2461.102438 2550.547528 2320.55825 2923.715858 2631.870129 2931.813833 4524.463809 2193.438274 2052.840377 1.187956106 1.198876671 1.242448052 1.13041339 1.424229516 1.282062725 1.428174282 2.204001762 1.068489444 1 11.00340574 -1 0.63986057 1.113133019 86.94361393 0.891853114 0.10631157 46.04879234 0.285873492 0.020284516 5598.025053 0.1 1 85.83048091 up VTSFSTPPT(ph)PER ddPTM_HeLa_Curcumin_4h_R1 1 VTSFSTPPTPER 12 0 B0QY16;Q6ICG6-3;Q6ICG6;Q6ICG6-2 B0QY16 KIAA0930 Uncharacterized protein KIAA0930 1 0 VTSFSTPPT(1)PER 161.25 0.00054938 14470000 2579.7 2127.3 2045.3 2399.5 2481.5 2669.1 2223 1730.4 2134.1 1955.9 TRUE FALSE FALSE 2375.514023 2311.174333 2121.100617 2389.571505 2451.909733 2115.498573 2285.371397 2257.990994 1899.994569 2023.867379 1.173749845 1.141959378 1.048043285 1.180695696 1.211497235 1.045275295 1.129210056 1.115681303 0.938794008 1 10.98289904 -9.401764355 1.065803308 0.998106567 1.133370448 0.563066384 0.0548682 0.362864059 0.720774095 0.037571259 0.009039262 3.96E-10 9.401764355 0.135263881 VTSGGVS(ph)ESPSGFSK ddPTM_HeLa_Curcumin_4h_R1 1 VTSGGVSESPSGFSK 15 0 E7EPP6;O14757-2;O14757-3;O14757 E7EPP6 CHEK1 Serine/threonine-protein kinase Chk1 1 0 VTS(0.116)GGVS(0.883)ESPSGFSK 175.6 9.32E-05 16466000 4572.8 3653 3703.9 3549.9 4202.9 4874.6 3352.7 2965 4885.2 3861.9 TRUE FALSE FALSE 4210.858055 3968.749043 3841.169792 3535.211454 4152.783163 3863.553012 3446.767739 3869.014851 4349.305782 3996.100738 1.053741718 0.993155404 0.96122947 0.884665249 1.039208828 0.966830735 0.862532745 0.968197527 1.088387423 1 11.96437724 -6.860133622 3.018009625 1.025280186 0.944831061 0.419014646 0.051008981 0.204402959 3.760075197 0.007966335 0.010797481 1.38E-07 6.860133622 -0.080449125 VTSGGVSES(ph)PSGFSK ddPTM_HeLa_Curcumin_4h_R1 1 VTSGGVSESPSGFSK 15 0 E7EPP6;O14757-2;O14757-3;O14757 E7EPP6 CHEK1 Serine/threonine-protein kinase Chk1 1 0 VTSGGVS(0.001)ES(0.855)PS(0.143)GFSK 210.08 6.23E-10 7650300 2674.3 2584.7 2381.1 2832.4 2129.3 3593 3446.5 1523.3 2632.1 2124.6 TRUE FALSE FALSE 2462.626333 2808.109951 2469.345661 2820.680279 2103.909488 2847.771299 3543.199514 1987.747158 2343.365215 2198.429692 1.120175161 1.277325339 1.123231582 1.283043206 0.957005583 1.295366101 1.611695624 0.904166808 1.06592684 1 11.10225768 -8.039573476 0.336999665 0.966395482 1.256483307 0.101971289 0.188378357 1.890417969 0.570551708 0.220373452 0.120925293 9.13E-09 8.039573476 0.290087825 VTSSITIYPSDSS(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 VTSSITIYPSDSSSPR 16 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 VTSSITIYPS(0.002)DS(0.09)S(0.601)S(0.307)PR 266.07 7.88E-52 31610000 2023.2 1936.8 2055.9 1790.4 1680.9 3663 3358.8 1461.8 2104.7 1394.7 TRUE FALSE FALSE 1863.061585 2104.208362 2132.093463 1782.991799 1660.856365 2903.252509 3453.038888 1907.496091 1873.819676 1443.165721 1.29095471 1.458050403 1.477372578 1.235472665 1.150842444 2.011724965 2.392683555 1.321744317 1.298409218 1 10.49502126 -4.928906203 0.232196782 0.974842704 2.452681238 0.289871974 0.337693012 5.936182504 0.356082252 0.319197502 2.528878015 1.18E-05 4.928906203 1.477838535 VTSSITIYPSDSSS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 VTSSITIYPSDSSSPR 16 0 Q86V48-2;Q86V48-3;Q86V48 Q86V48-2 LUZP1 Leucine zipper protein 1 1 0 VTSSITIYPSDS(0.02)S(0.129)S(0.852)PR 268.5 5.50E-52 31975000 2714.2 2202.7 2412.7 2279.1 2749.7 5062.8 3385.5 1996.3 2893.5 2311.4 TRUE FALSE FALSE 2499.368206 2393.091573 2502.116784 2269.669688 2716.911623 4012.71821 3480.488018 2604.96268 2576.090289 2391.720978 1.045008272 1.000573058 1.046157477 0.948969261 1.135965127 1.677753487 1.455223268 1.089158269 1.077086463 1 11.22383338 -5.477676523 8.13220757 1.01847704 1.41238301 0.616388296 0.136806584 0.144677375 23.93445388 0.018212829 0.040498806 3.33E-06 5.477676523 0.39390597 CSMSSSADFS(ph)DEDDFSQK ddPTM_HeLa_Curcumin_4h_R1 1 CSMSSSADFSDEDDFSQK 18 0 F6QMI7;E7ETB9;Q5T0V7;Q03001-11 F6QMI7 DST Dystonin 1 0 CSMSSSADFS(1)DEDDFSQK 183.7 5.59E-20 0 1079.5 971.1 1104.3 1234.2 1060.3 1175.6 867.29 448.65 1101.1 1195.8 TRUE FALSE FALSE 994.0564359 1055.037557 1145.226329 1229.093207 1047.656615 931.7673083 891.6238232 585.4413197 980.3120848 1237.353961 0.803372735 0.852656225 0.925544642 0.993323856 0.846691123 0.753032146 0.720589137 0.473139731 0.792264878 1 10.27304255 -3.929118599 0.805708002 0.908096211 6.82E-19 0.759102311 0.07128284 1.526224676 0.499584336 0.01349119 1.401259081 0.000117728 3.929118599 -0.908096211 down QPLSEASNQQPLS(ph)GGEEK ddPTM_HeLa_Curcumin_4h_R1 4 QPLSEASNQQPLSGGEEK 18 0 Q9NQW6;Q9NQW6-2;C9JJT6 Q9NQW6 ANLN Actin-binding protein anillin 1 0 QPLSEASNQQPLS(1)GGEEK;QPLSEASNQQPLS(1)GGEEK;QPLSEASNQQPLS(1)GGEEK;QPLSEASNQQPLS(1)GGEEK ;;; 183.21 2.66E-13 60101000 8803.41 7440.19 8219.13 8325.19 8660.52 9406.9 6966.34 3383.18 7990.82 8966.32 TRUE FALSE FALSE 8106.610809 8083.286871 8523.738188 8290.74257 8557.248955 7455.802902 7161.796751 4414.696008 7114.247038 9277.898953 0.873755023 0.871241098 0.918714273 0.8936013 0.922326164 0.803608979 0.771920107 0.475829283 0.766795055 1 13.17958242 -3.928341097 0.900922648 0.93011874 2.18E-18 0.765561422 0.066115384 0.936374935 0.379611108 0.008651336 0.984265278 0.000117939 3.928341097 -0.93011874 down VTSSVPLPS(ph)GSTSSPGR ddPTM_HeLa_Curcumin_4h_R1 1 VTSSVPLPSGSTSSPGR 17 0 Q15036-2;Q15036 Q15036-2 SNX17 Sorting nexin-17 1 0 VTSSVPLPS(0.404)GS(0.404)T(0.108)S(0.058)S(0.024)PGR 170.35 6.49E-05 36244000 1871.3 1812.7 1955.3 1931.6 2173.2 2271.9 1501.5 1936.3 1731.5 1785.9 TRUE FALSE FALSE 1723.18463 1969.381711 2027.765138 1923.607551 2147.286009 1800.68233 1543.628049 2526.668956 1541.558782 1847.959892 0.932479454 1.065705873 1.097299323 1.040935769 1.161976523 0.974416349 0.835314692 1.367274781 0.834194935 1 10.85171773 -7.245779072 21.71133871 0.968115303 1.066873598 0.192012919 0.13537887 226.8567583 314511.1913 0.019957754 0.024372057 5.68E-08 7.245779072 0.098758295 SVNVS(ph)LTQEELDSGLDELSVR ddPTM_HeLa_Curcumin_4h_R1 1 SVNVSLTQEELDSGLDELSVR 21 0 Q9Y2D5-5;Q9Y2D5-7;Q9Y2D5-6;Q9Y2D5-4;Q9Y2D5;C9JVY5 Q9Y2D5-5 AKAP2 A-kinase anchor protein 2 1 0 S(0.018)VNVS(0.93)LT(0.052)QEELDSGLDELSVR 131.75 1.26E-05 2304900 766.43 705.39 667.16 615.65 640.02 673.54 550.78 248.11 826.64 641.01 TRUE FALSE FALSE 705.7662568 766.3607684 691.8855365 613.1026034 632.3881795 533.8402116 566.2334045 323.7575968 735.9596602 663.2850498 1.064046682 1.155401842 1.04311945 0.924342564 0.953418413 0.804842823 0.853680336 0.488112308 1.109567689 1 9.373485198 -3.923054569 0.658610604 1.039396419 1.27E-15 0.851932827 0.070441384 1.231324274 0.272401414 0.011899573 1.061423238 0.000119384 3.923054569 -1.039396419 down VTTEIQLPS(ph)QSPVEEQSPASLSSLR ddPTM_HeLa_Curcumin_4h_R1 1 VTTEIQLPSQSPVEEQSPASLSSLR 25 0 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2;E9PMP7;H0Y424 Q8WWI1-3 LMO7 LIM domain only protein 7 1 0 VT(0.001)T(0.002)EIQLPS(0.613)QS(0.381)PVEEQS(0.002)PASLSSLR 58.319 0.0028619 48961000 2746.2 2093.3 2328.4 2592.6 2042.6 3104.6 2469.6 6055.4 2792.9 2391.9 TRUE FALSE FALSE 2528.835372 2274.235524 2414.692552 2581.872508 2018.243329 2460.670964 2538.890329 7901.663584 2486.525857 2475.018347 1.021744091 0.918876229 0.975626122 1.043173078 0.815445805 0.994203121 1.02580667 3.192567681 1.004649465 1 11.2732235 -4.261378221 6.785355361 0.989703786 3.229681173 0.991062137 0.063100255 0.006982273 2.199770031 0.008662806 0.071360129 5.48E-05 4.261378221 2.239977387 GLNVIGASDQS(ph)PLQS(ph)PSNLR ddPTM_HeLa_Curcumin_4h_R1 1 GLNVIGASDQSPLQSPSNLR 20 0 A0JP02;B4DJX4;Q9HAU0-8;Q9HAU0;Q9HAU0-2;Q9HAU0-4;Q9HAU0-6;Q9HAU0-5;H0YGJ6 A0JP02 PLEKHA5 Pleckstrin homology domain-containing family A member 5 2 0 GLNVIGAS(0.09)DQS(0.998)PLQS(0.876)PS(0.036)NLR 111.63 0.00051651 5114100 1242.4 1063.6 1283.7 1397.9 1157.1 1538.4 1763 1734.5 1332.5 830.64 TRUE FALSE FALSE 1144.062729 1155.532845 1331.275051 1392.11586 1143.302338 1219.318499 1812.465035 2263.341065 1186.328084 859.5046782 1.331072137 1.344417167 1.548886335 1.619672232 1.330187452 1.418629275 2.108732019 2.633308605 1.380246221 1 9.747361682 -1 0.391142469 1.157760183 23.32857347 0.819675733 0.188623709 17.75356015 0.212385283 0.051491668 304.6254279 0.1 1 22.17081329 up VTTHPLAK ddPTM_HeLa_Curcumin_4h_R1 1 VTTHPLAK 8 0 Q99497;K7ELW0;K7EN27 Q99497 PARK7 Protein deglycase DJ-1 0 0 89.752 0.0069811 6993500 7960.4 6856.4 7100 5561.6 7119.1 9100.6 6659.7 6777.6 7376 7383.1 FALSE FALSE TRUE 7330.32594 7449.036664 7363.132246 5538.587573 7034.209382 7213.032975 6846.553258 8844.05904 6566.871254 7639.662175 0.959509174 0.975047914 0.963803382 0.724978074 0.920748748 0.944156012 0.896185342 1.15765054 0.859576131 1 12.89929313 -6.504468565 24.85038819 0.979408588 0.919051398 0 0.105332241 1451.041056 1958641.998 0.014676128 0.022164112 3.13E-07 6.504468565 -0.06035719 VTVAGLAGKDPVQCSR ddPTM_HeLa_Curcumin_4h_R1 2 VTVAGLAGKDPVQCSR 16 1 Q99497;K7ELW0 Q99497 PARK7 Protein deglycase DJ-1 0 0 ; ; 132.65 0.0004442 19945900 2051.63 1496.78 1616.22 1389.15 1629.17 2294.14 1779.74 2001.04 2037.5 1763.09 FALSE FALSE TRUE 1889.241321 1626.154994 1676.118535 1383.402065 1609.743212 1818.309504 1829.674714 2611.147884 1813.991348 1824.357246 1.035565443 0.891357763 0.918744691 0.758295596 0.882361837 0.996685001 1.002914708 1.431270048 0.994318054 1 10.83317255 -4.256697778 4.148106122 0.972641848 1.471012864 0.74970318 0.083294951 0.108058582 4.053594099 0.013665848 0.160633038 5.54E-05 4.256697778 0.498371016 VTVDTGVIPASEEKAET(ph)PTAAEDDNEGDKK ddPTM_HeLa_Curcumin_4h_R1 1 VTVDTGVIPASEEKAETPTAAEDDNEGDKK 30 2 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 0 VTVDT(0.006)GVIPAS(0.236)EEKAET(0.713)PT(0.046)AAEDDNEGDKK 55.662 0.0012762 24542000 1166.9 1069.1 1196.1 1109.9 1260.5 1269.5 1187.3 555.82 1040.4 1045.4 TRUE FALSE FALSE 1074.538634 1161.50824 1240.428518 1105.307528 1245.469361 1006.19139 1220.612443 725.2869593 926.270723 1081.727572 0.993354206 1.073753013 1.146710641 1.021798423 1.151370634 0.930170789 1.128391726 0.670489482 0.856288355 1 10.07912149 -4.251122446 24.94981682 1.026012748 0.670489279 0.58789415 0.090992437 639.0626418 1545437.85 0.010052987 0.187664591 5.61E-05 4.251122446 -0.355523469 VTVLFAGQHIAK ddPTM_HeLa_Curcumin_4h_R1 2 VTVLFAGQHIAK 12 0 P21333-2;P21333;F8WE98;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 120.03 0.00030942 21006000 12204.4 7827.5 11758.3 9112.1 11750 18340.6 14775.9 12863.2 9625 9951.1 FALSE FALSE TRUE 11238.40886 8504.074221 12194.07294 9074.396545 11609.88892 14536.55282 15190.47199 16785.13047 8569.161581 10296.89998 1.091436149 0.825886843 1.184247003 0.881274613 1.127513032 1.411740703 1.475247114 1.630114937 0.832207907 1 13.32992244 -5.171563407 2.017726991 1.026238719 1.558791017 0.801301386 0.1188176 0.0943861 0.733066794 0.014051167 0.047682563 6.74E-06 5.171563407 0.532552297 VVASGPGLEHGK ddPTM_HeLa_Curcumin_4h_R1 2 VVASGPGLEHGK 12 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 102.05 0.0020786 12370600 6259.8 6060.1 4938.4 5193.5 6602.1 10272.2 7166.6 6242.4 7109.3 5335.6 FALSE FALSE TRUE 5764.330225 6583.908041 5121.421448 5172.010673 6523.374269 8141.629928 7367.675508 8145.679024 6329.427577 5521.011703 1.044071365 1.1925184 0.927623726 0.936786761 1.181554146 1.474662683 1.334479241 1.47539608 1.146425314 1 12.43071694 -5.461460089 3.723269717 1.022967533 1.41633892 0.793640598 0.087640798 0.064941908 1.77482127 0.011188399 0.025720491 3.46E-06 5.461460089 0.393371387 VVDALGNAIDGK ddPTM_HeLa_Curcumin_4h_R1 1 VVDALGNAIDGK 12 0 P25705;P25705-2;K7ERX7;K7EK77;K7EQH4;K7EJP1;K7ENJ4 P25705 ATP5A1 "ATP synthase subunit alpha, mitochondrial" 0 0 121.68 0.00097264 2476700 2186.2 1813 2188.1 2330 2394.8 3762.6 2309.3 1984 2651.7 1672.9 FALSE FALSE TRUE 2013.159963 1969.707641 2269.192911 2320.359077 2366.243574 2982.194347 2374.092743 2588.912467 2360.815144 1731.03315 1.16298175 1.137879792 1.310889344 1.340447511 1.366954511 1.722782921 1.371488895 1.495588034 1.363818563 1 10.75741764 -6.504827345 0.518114754 1.035521011 1.548255887 0.451075325 0.140581547 0.304728375 0.166668267 0.028221 0.064480113 3.13E-07 6.504827345 0.512734876 VVDDEIYYFR ddPTM_HeLa_Curcumin_4h_R1 1 VVDDEIYYFR 10 0 Q86U86-8;Q86U86;E7EVG2;Q86U86-5;Q86U86-7;Q86U86-3;Q86U86-2;Q86U86-4;Q86U86-9 Q86U86-8 PBRM1 Protein polybromo-1 0 0 181.55 0.0023624 3511100 1184.4 1143.6 1009.8 1059.4 1007.1 1601.1 1077.6 880.83 1212.8 869.36 FALSE FALSE TRUE 1090.65349 1242.447688 1047.224076 1055.016484 995.0909903 1269.013812 1107.834556 1149.391012 1079.758874 899.5701953 1.212416214 1.381157018 1.164138254 1.172800621 1.106184926 1.410689036 1.231515408 1.277711309 1.200305301 1 9.813092052 -8.923470304 0.616584304 0.98361189 1.248205076 0.115564734 0.108359034 0.573989925 0.38084007 0.07980377 0.021401958 1.19E-09 8.923470304 0.264593186 VVDFGSAT(ph)YDDEHHS(ph)TLVSTRHYR ddPTM_HeLa_Curcumin_4h_R1 1 VVDFGSATYDDEHHSTLVSTRHYR 24 1 F8WBF5;P49759;P49759-3;B8ZZR0;A0A087WVK0;Q9HAZ1 F8WBF5;Q9HAZ1 CLK1;CLK4 Dual specificity protein kinase CLK1;Dual specificity protein kinase CLK4 2 0 VVDFGS(0.28)AT(0.387)Y(0.34)DDEHHS(0.89)T(0.084)LVS(0.011)T(0.004)RHY(0.004)R 44.054 0.018612 9885600 2003.5 1775.6 1743.6 1836 2048.2 2235.6 1724.5 1185.5 2056.3 1683.2 TRUE FALSE FALSE 1844.920861 1929.074952 1808.21935 1828.403118 2023.776553 1771.91136 1772.884829 1546.953493 1830.729035 1741.691075 1.05926986 1.107587321 1.038197517 1.049786122 1.161960684 1.017351117 1.017910038 0.888190515 1.051121557 1 10.76627304 -4.203713495 2.192271106 1.045394262 0.831911594 0.550511358 0.045311026 0.549973873 2.613359122 0.007121493 0.240488507 6.26E-05 4.203713495 -0.213482669 VVDLMAHMASK ddPTM_HeLa_Curcumin_4h_R1 1 VVDLMAHMASK 11 0 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 92.866 0.0050418 1547000 1880.4 1615.1 2271.2 1393.5 2471.2 3775 3080.3 2751.7 1765.2 1781.7 FALSE FALSE TRUE 1731.564356 1754.702047 2355.37267 1387.734066 2441.732554 2992.022447 3166.724928 3590.680663 1571.561976 1843.613942 0.939222858 0.95177304 1.27758454 0.752724871 1.324427256 1.622911597 1.717672477 1.947631541 0.852435502 1 10.84832087 -5.286553522 1.683894974 0.979127437 1.842114347 0.860474525 0.144804937 0.088497019 0.474323403 0.019101026 0.064711689 5.17E-06 5.286553522 0.86298691 VVDLMAHMASKE ddPTM_HeLa_Curcumin_4h_R1 4 VVDLMAHMASKE 12 1 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 ;;; ;;; 145.29 0.0012648 68264300 30787.7 21705.1 23964.4 21937.5 24505.4 49384.8 33403.8 31068.1 32222 27821.2 FALSE FALSE TRUE 28350.82106 23581.19213 24852.54175 21846.72844 24213.18911 39141.8358 34341.02073 40540.62067 28687.32722 28787.98463 0.984814374 0.819133136 0.863295645 0.758883566 0.841086635 1.359658771 1.192894229 1.408247962 0.996503492 1 14.81317917 -5.256708621 24.99944427 0.942599384 1.307529732 0.785038828 0.099787201 174.3216596 921189.194 0.016163699 0.039764389 5.54E-06 5.256708621 0.364930348 VVDNS(ph)PPPALPPK ddPTM_HeLa_Curcumin_4h_R1 1 VVDNSPPPALPPK 13 0 Q13905-2;Q13905;Q13905-4;Q13905-3 Q13905-2 RAPGEF1 Rap guanine nucleotide exchange factor 1 1 0 VVDNS(1)PPPALPPK 97.223 0.008466 20410000 7122.5 5852 6219.8 6836.2 6289.8 7153.9 5066.6 3262.5 7595.2 6487.4 TRUE FALSE FALSE 6558.746609 6357.820804 6450.311259 6807.913616 6214.798243 5670.100499 5208.75516 4257.221231 6762.025562 6712.836667 0.977045463 0.947113883 0.960892031 1.014163453 0.925808053 0.844665345 0.775939505 0.634191094 1.007327587 1 12.71270682 -4.396444065 0.807463913 0.987102172 0.475020095 0.95962223 0.023384526 0.272220439 0.144430241 0.003853289 0.119108651 4.01E-05 4.396444065 -0.512082076 VVDPFSK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 VVDPFSKK 8 1 P61247;H0Y9Y4;E9PFI5;H0Y8L7;D6RI02 P61247 RPS3A 40S ribosomal protein S3a 0 1 VVDPFSK(1)K 109.71 0.0022447 5083200 3877.1 5091.1 3788.5 4066.1 7700.2 10083 7344.3 6585.7 10102 4240.7 FALSE TRUE FALSE 3570.223444 5531.151998 3928.905143 4049.275556 7608.380144 7991.672141 7550.361292 8593.649613 8993.835874 4388.064009 0.813621551 1.260499388 0.895361858 0.922793183 1.733880848 1.821229618 1.720658877 1.958414826 2.049613646 1 12.09936886 -5.740300412 5.546618398 0.937244849 1.811557 0.344268872 0.3735626 0.036019862 3.217846583 0.019456959 0.038314121 1.82E-06 5.740300412 0.874312151 VVDRDSEEAEIIR ddPTM_HeLa_Curcumin_4h_R1 4 VVDRDSEEAEIIR 13 1 P09874 P09874 PARP1 Poly [ADP-ribose] polymerase 1 0 0 ;;; ;;; 164.48 0.00015095 46791100 7338.4 5969.1 7402.8 6946.2 7443.1 9120.4 6817.5 6487.8 7643.3 7538.2 FALSE FALSE TRUE 6757.557897 6485.042406 7677.15428 6917.458465 7354.345894 7228.726232 7008.780702 8465.900354 6804.849113 7800.151889 0.866336706 0.831399503 0.984231383 0.88683638 0.942846498 0.926741727 0.898544131 1.085350705 0.872399565 1 12.9292865 -4.255231431 24.66679671 0.926298584 1.085350791 0.483692672 0.051861432 481.1076841 1911579.156 0.008340351 0.102623806 5.56E-05 4.255231431 0.159052207 VVDRDSEEAEIIRK ddPTM_HeLa_Curcumin_4h_R1 1 VVDRDSEEAEIIRK 14 2 P09874 P09874 PARP1 Poly [ADP-ribose] polymerase 1 0 0 61.03 0.018555 6197200 1479.3 1086 1532.2 1495.4 1252.2 1552.5 1165.1 1256.8 1730.8 1668.1 FALSE FALSE TRUE 1362.211844 1179.869001 1588.98468 1489.212431 1237.268333 1230.494 1197.78957 1639.992534 1540.93557 1726.066351 0.789200162 0.683559471 0.920581459 0.862778207 0.716813889 0.712889165 0.693941788 0.950132962 0.892744111 1 10.75327221 -9.137977451 0.65942901 1.01928563 0.783605269 0.264929486 0.095509209 0.674733137 0.471548569 0.090197642 0.019720036 7.28E-10 9.137977451 -0.235680362 DLISLDS(ph)SPAKER ddPTM_HeLa_Curcumin_4h_R1 1 DLISLDSSPAKER 13 1 Q9UN79 Q9UN79 SOX13 Transcription factor SOX-13 1 0 DLISLDS(0.5)S(0.5)PAKER 86.539 0.0069029 6189000 2836.3 2710.5 2981.5 2977.3 2329.3 3298.4 2301 1070.6 3425.1 3076.3 TRUE FALSE FALSE 2611.803862 2944.783542 3091.997013 2964.980721 2301.524619 2614.274659 2365.559867 1397.021012 3049.375099 3183.201196 0.820496004 0.925101293 0.971348282 0.93144622 0.723022039 0.821272203 0.743138659 0.438872985 0.957958643 1 11.63626263 -3.909279308 0.714118008 0.917756763 7.96E-20 0.80190002 0.071299344 1.7058753 0.434266935 0.014275888 1.413856481 0.000123231 3.909279308 -0.917756763 down VVDYSQFQES(ph)DDADEDYGR ddPTM_HeLa_Curcumin_4h_R1 25 VVDYSQFQESDDADEDYGR 19 0 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYS(0.003)QFQES(0.997)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDY(0.009)S(0.013)QFQES(0.978)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYS(0.004)QFQES(0.996)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYS(0.003)QFQES(0.997)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR;VVDYSQFQES(1)DDADEDYGR ;;;;;;;;;;;;;;;;;;;;;;;; 256.33 8.21E-61 4153539100 40140.69 35193.39 38155.113 38665.462 42988.9 43535.94 39400.1 38580.07 37297.41 33398.25 TRUE FALSE FALSE 36963.51203 38235.34981 39569.17505 38505.47456 42476.28544 34506.09529 40505.56077 50342.95574 33205.97744 34558.8367 1.069582068 1.106384169 1.144979948 1.114200541 1.229100557 0.998473866 1.172075354 1.456731781 0.960853449 1 15.07676703 -1.000000147 0.900662682 1.058815521 199.999989 0.67180005 0.078049445 376.9222426 0.786335906 0.012327237 154182.9928 0.099999966 1.000000147 198.9411735 VVDYSQFQES(ph)DDADEDYGRDSGPPTK ddPTM_HeLa_Curcumin_4h_R1 8 VVDYSQFQESDDADEDYGRDSGPPTK 26 1 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 VVDY(0.003)S(0.026)QFQES(0.95)DDADEDY(0.017)GRDS(0.003)GPPTK;VVDYS(0.001)QFQES(0.999)DDADEDYGRDSGPPTK;VVDY(0.007)S(0.027)QFQES(0.916)DDADEDY(0.037)GRDS(0.013)GPPTK;VVDY(0.226)S(0.226)QFQES(0.547)DDADEDY(0.001)GRDSGPPTK;VVDY(0.017)S(0.023)QFQES(0.957)DDADEDY(0.002)GRDS(0.001)GPPTK;VVDY(0.004)S(0.004)QFQES(0.968)DDADEDY(0.02)GRDS(0.004)GPPTK;VVDYS(0.002)QFQES(0.998)DDADEDY(0.001)GRDSGPPTK;VVDYS(0.007)QFQES(0.908)DDADEDY(0.072)GRDS(0.012)GPPTK ;;;;;;; 114.15 1.41E-08 1613600800 19677.79 16320.62 16998.74 18977.86 18134.29 20966.44 16419.7 18033.33 20689.44 18325.44 TRUE FALSE FALSE 18120.27216 17731.30167 17628.72826 18899.33464 17918.05044 16617.764 16880.39259 23531.6093 18419.86019 18962.24768 0.955597272 0.935084383 0.929675034 0.996682195 0.944932834 0.876360455 0.890210532 1.240971519 0.971396456 1 14.21084236 -4.252564768 24.84776911 0.960038702 1.240971676 0.821329342 0.040913645 392.7758344 1099696.172 0.006521312 0.105018517 5.59E-05 4.252564768 0.280932975 VVDYSQFQES(ph)DDADEDYGRDSGPPTKK ddPTM_HeLa_Curcumin_4h_R1 5 VVDYSQFQESDDADEDYGRDSGPPTKK 27 2 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 1 0 VVDY(0.001)S(0.021)QFQES(0.956)DDADEDY(0.007)GRDS(0.006)GPPT(0.01)KK;VVDYS(0.002)QFQES(0.997)DDADEDYGRDSGPPTKK;VVDYS(0.006)QFQES(0.983)DDADEDY(0.005)GRDS(0.005)GPPT(0.001)KK;VVDY(0.013)S(0.06)QFQES(0.927)DDADEDYGRDSGPPTKK;VVDY(0.002)S(0.325)QFQES(0.671)DDADEDY(0.001)GRDSGPPT(0.001)KK ;;;; 100.66 9.27E-07 1620170000 14404.5 10962.58 11739.81 13038.2 11368.14 16502.7 10791.37 12618.74 17272.4 13384.5 TRUE FALSE FALSE 13264.36863 11910.13657 12174.89769 12984.25138 11232.58236 13079.854 11094.1468 16466.13574 15377.66093 13849.61038 0.957743089 0.85996185 0.879078714 0.937517448 0.811039592 0.944420358 0.801043964 1.188924113 1.110331664 1 13.75755777 -7.581375182 2.82166771 0.983854474 0.909188718 0.131612545 0.110324718 0.414164234 6.891018272 0.017423984 0.018460981 2.62E-08 7.581375182 -0.074665756 VVDYSQFQESDDADEDYGR ddPTM_HeLa_Curcumin_4h_R1 1 VVDYSQFQESDDADEDYGR 19 0 Q9H1E3 Q9H1E3 NUCKS1 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 0 0 128.71 0.0012056 8237600 625.18 599.82 608.39 602.7 530.34 790.02 578.2 728.74 694.32 585.75 FALSE FALSE TRUE 575.6963433 651.6657681 630.9374686 600.2061871 524.0160419 626.1609466 594.4227359 950.9294713 618.1548331 606.1047689 0.949829754 1.075170171 1.040970969 0.990268049 0.864563469 1.033090282 0.98072605 1.568919303 1.019881157 1 9.243423384 -4.261229234 24.95547294 0.984256086 1.568919478 0.905201813 0.055627192 3.344427887 396886.5075 0.00754409 0.058590031 5.48E-05 4.261229234 0.584663393 VVEAVNS(ph)DSDS(ph)EFGIPK ddPTM_HeLa_Curcumin_4h_R1 2 VVEAVNSDSDSEFGIPK 17 0 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 2 0 VVEAVNS(0.995)DS(0.219)DS(0.786)EFGIPK;VVEAVNS(0.996)DS(0.119)DS(0.885)EFGIPK ; 91.616 0.0032249 4256400 4319.5 2338.13 3586.3 4166 3525.1 3902.8 3046.62 2185.89 4322.5 3605 TRUE FALSE FALSE 3977.607017 2540.227539 3719.211433 4148.762196 3483.065485 3093.315286 3132.099958 2852.357798 3848.332564 3730.273482 1.066304397 0.680976221 0.997034521 1.11218714 0.933729257 0.829246247 0.83964352 0.764651121 1.031648908 1 11.86506569 -2.628014227 0.337039577 1.02312551 1.82E-12 0.279590868 0.113551569 15.7509979 0.535050128 0.037927747 8.306098094 0.002354972 2.628014227 -1.02312551 VVEAVNSDS(ph)DSEFGIPK ddPTM_HeLa_Curcumin_4h_R1 1 VVEAVNSDSDSEFGIPK 17 0 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 1 0 VVEAVNS(0.156)DS(0.422)DS(0.422)EFGIPK 138.55 1.25E-05 0 2299.5 1020.6 2041.5 2450.8 1782.4 2182.4 1367.4 966.51 2236.4 1834.3 TRUE FALSE FALSE 2117.492149 1108.816116 2117.159786 2440.659239 1761.146044 1729.745639 1405.765564 1261.19445 1991.072515 1898.041788 1.115619351 0.584189517 1.115444243 1.285882773 0.927875274 0.911331694 0.740639944 0.664471382 1.049014056 1 10.89029604 -4.864215901 1.685784557 1.035431056 0.662942049 0.341461733 0.17021649 0.34596496 1.758541131 0.025000864 0.14318902 1.37E-05 4.864215901 -0.372489007 VVEAVNSDSDS(ph)EFGIPK ddPTM_HeLa_Curcumin_4h_R1 1 VVEAVNSDSDSEFGIPK 17 0 Q02880-2;Q02880 Q02880-2 TOP2B DNA topoisomerase 2-beta 1 0 VVEAVNS(0.001)DS(0.008)DS(0.991)EFGIPK 109.1 0.001238 10178000 13119 9787.5 10645 11303 10829 10811 6622.5 4926 10637 9447.7 TRUE FALSE FALSE 12080.61731 10633.48789 11039.51306 11256.23118 10699.87125 8568.676735 6808.309526 6427.914723 9470.147712 9776.006872 1.235741491 1.087712808 1.129245633 1.151414 1.094503245 0.876500687 0.696430518 0.657519456 0.968713283 1 13.25502958 -5.013710707 2.021086897 1.116994594 0.660197602 0.843391723 0.072589816 0.105131672 0.821955706 0.012698758 0.050840537 9.69E-06 5.013710707 -0.456796992 ASEDS(ph)EEEPSGK ddPTM_HeLa_Curcumin_4h_R1 2 ASEDSEEEPSGK 12 0 Q8IY33-4;Q8IY33-2;Q8IY33 Q8IY33-4 MICALL2 MICAL-like protein 2 1 0 ASEDS(1)EEEPSGK;ASEDS(0.995)EEEPS(0.005)GK ; 176.99 0.00013512 13995400 7952 6225.8 5949.7 6914.1 6777.3 7465 5984.9 2441.51 7800.8 7114.6 TRUE FALSE FALSE 7322.590809 6763.93041 6170.201116 6885.491286 6696.485124 5916.674852 6152.820186 3185.91516 6945.071757 7361.83182 0.994669668 0.918783609 0.838133941 0.935295923 0.909622128 0.803696009 0.835772989 0.432761198 0.943389081 1 12.84584908 -3.900672818 0.675954523 0.980237357 1.05E-43 0.809402054 0.068059618 1.325627245 0.301699773 0.011567916 1.113928054 0.000125698 3.900672818 -0.980237357 down VVESPDFS(ph)KDEDYLGK ddPTM_HeLa_Curcumin_4h_R1 2 VVESPDFSKDEDYLGK 16 1 Q9Y6Y8 Q9Y6Y8 SEC23IP SEC23-interacting protein 1 0 VVES(0.056)PDFS(0.944)KDEDYLGK;VVES(0.158)PDFS(0.838)KDEDY(0.004)LGK ; 74.853 0.0081031 91120000 9683.2 7476.4 8025.3 7528.8 7725.1 7450.7 6343.5 6938.6 7290.9 7784 TRUE FALSE FALSE 8916.764502 8122.626702 8322.724678 7497.64782 7632.983228 5905.340833 6521.481537 9054.147199 6491.106511 8054.493421 1.107054663 1.00845904 1.033302064 0.930865224 0.947667697 0.733173463 0.809669981 1.124111316 0.805898791 1 12.97557814 -6.13174776 1.744461633 1.048884836 0.883229205 0.000328879 0.124751515 0.297905199 1.778352266 0.015824513 0.030085347 7.38E-07 6.13174776 -0.165655631 VVEVGSK ddPTM_HeLa_Curcumin_4h_R1 2 VVEVGSK 7 0 P14618;P14618-3;B4DNK4;P14618-2;H3BTN5;H3BQ34 P14618;P14618-2 PKM Pyruvate kinase PKM;Pyruvate kinase 0 0 ; ; 111.82 0.012704 22987000 12281.8 19902.2 9769.3 8738.4 6543.6 12378.7 10428.6 9452.4 8641.1 10950.4 FALSE FALSE TRUE 11309.68257 21622.45749 10131.35885 8702.242816 6465.571844 9811.218083 10721.19845 12334.39325 7693.192949 11330.92558 0.998125218 1.908269305 0.894133385 0.768008116 0.570612859 0.865879668 0.946189115 1.088560079 0.678955386 1 13.46797809 -6.544009759 24.9996534 1.083177641 0.838128233 0.157125198 0.317800099 374.5580504 443130.0396 0.04775876 0.067544431 2.86E-07 6.544009759 -0.245049407 VVFPPGS(ph)PIPLRR ddPTM_HeLa_Curcumin_4h_R1 2 VVFPPGSPIPLRR 13 1 A0A1B0GTU4;A0A1B0GV30 A0A1B0GTU4 1 0 VVFPPGS(1)PIPLRR;VVFPPGS(1)PIPLRR ; 119.77 0.0011847 63270000 3725.7 2754.1 2749.2 3233.3 3356.3 3860.8 2606.4 1694.44 3734.4 3045.3 TRUE FALSE FALSE 3430.806914 2992.152132 2851.08777 3219.921461 3316.278315 3060.02656 2679.528569 2211.066956 3324.745663 3151.123948 1.088756574 0.949550757 0.904784394 1.02183269 1.052411257 0.971090509 0.850340581 0.701675654 1.055098345 1 11.62165079 -4.492873758 1.577045906 1.024719768 0.654287154 0.778266184 0.051930164 0.25803978 0.828200532 0.008893 0.127744738 3.21E-05 4.492873758 -0.370432614 VVFVFGPDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VVFVFGPDKK 10 1 P30041 P30041 PRDX6 Peroxiredoxin-6 0 1 ; VVFVFGPDK(1)K;VVFVFGPDK(1)K 127.3 0.00061928 1927990 1542.88 1593.48 1540.02 1329.8 3130.8 4223 2957.8 2533.5 3426.8 1539.9 FALSE TRUE FALSE 1420.75942 1731.213311 1597.094496 1324.29764 3093.467255 3347.102197 3040.787907 3305.952487 3050.888613 1593.41141 0.89164632 1.086482311 1.002311447 0.83110842 1.941411512 2.100588822 1.90835078 2.074763909 1.914689824 1 10.6379031 -5.745773982 10.42404998 0.956171412 2.006868373 0.635092687 0.314156536 0.032983746 20.7537865 0.011972867 0.023511652 1.80E-06 5.745773982 1.05069696 VVFVFGPDKK ddPTM_HeLa_Curcumin_4h_R1 1 VVFVFGPDKK 10 1 P30041 P30041 PRDX6 Peroxiredoxin-6 0 0 79.986 0.014181 0 308.51 0 291.45 207.42 217.13 442.35 304.41 381.62 252.26 161.34 FALSE FALSE TRUE 284.091108 0 302.2513934 206.561751 214.5408666 350.6016237 312.9509253 497.9741812 224.5877091 166.946553 1.701688971 0 1.810468009 1.237292698 1.285087129 2.100083035 1.874557574 2.982835957 1.345267124 1 7.383242496 -3.104203498 0.628448808 1.245653836 9.065708225 0.557763061 0.491568655 6.940351494 0.63710517 0.086235353 54.84866915 0.000786677 3.104203498 7.820054389 VVGAVGSDEK ddPTM_HeLa_Curcumin_4h_R1 1 VVGAVGSDEK 10 0 F2Z3J9;Q14914-2;Q14914 F2Z3J9 PTGR1 Prostaglandin reductase 1 0 0 101.25 0.0097454 2133300 3632.7 2913.9 3104.5 3443.4 3124.7 3332.5 2906.3 2921.2 3600.3 3119.3 FALSE FALSE TRUE 3345.167962 3165.764532 3219.555501 3429.152123 3087.439993 2641.301935 2987.842956 3811.860432 3205.356098 3227.695443 1.036395168 0.980812653 0.997478095 1.062415021 0.956546257 0.818324399 0.925689245 1.180985164 0.993078856 1 11.65628874 -5.719028846 21.90272933 1.015740004 0.95633163 0.040817254 0.086818256 75.33991306 38907.20063 0.012130011 0.024259541 1.91E-06 5.719028846 -0.059408373 VVGDRENGSDNLPSS(ph)AGSGDKPLS(ph)DPAPF ddPTM_HeLa_Curcumin_4h_R1 1 VVGDRENGSDNLPSSAGSGDKPLSDPAPF 29 2 O43399;O43399-5;O43399-7;O43399-2;O43399-4;O43399-3;A0A087WZ51;O43399-6 O43399 TPD52L2 Tumor protein D54 2 0 VVGDRENGS(0.001)DNLPS(0.081)S(0.844)AGS(0.092)GDKPLS(0.982)DPAPF 48.773 0.014101 2849100 591.58 387.37 508.15 560.4 566.89 695.42 590.41 605.12 687.23 504.17 TRUE FALSE FALSE 544.7558188 420.8525367 526.982486 558.0812133 560.130207 551.182053 606.9753156 789.6183024 611.8425884 521.68987 1.04421391 0.806710195 1.010145139 1.069756661 1.07368427 1.056532022 1.163479206 1.513577985 1.172809026 1 9.02704861 VVGQT(ph)TPESFEK ddPTM_HeLa_Curcumin_4h_R1 2 VVGQTTPESFEK 12 0 Q02952-3;Q02952-2;Q02952 Q02952-3 AKAP12 A-kinase anchor protein 12 1 0 VVGQT(0.333)T(0.333)PES(0.333)FEK;VVGQT(0.844)T(0.078)PES(0.078)FEK ; 166.24 0.00035463 49799000 8383.9 7450.5 8235.7 8395.5 9721.4 8874.3 8717.2 9340 8629.6 7616.5 TRUE FALSE FALSE 7720.305468 8094.488021 8540.922287 8360.761646 9605.478654 7033.670146 8961.781171 12187.723 7682.95447 7881.172808 0.979588401 1.02706643 1.083712094 1.060852471 1.218787976 0.892464906 1.137112634 1.546435194 0.974849132 1 12.94419462 -4.30157815 3.171468241 1.015340036 1.601785186 0.776719569 0.082457514 0.098721107 1.576378039 0.011264405 0.135107934 4.99E-05 4.30157815 0.58644515 VVGSELIQK ddPTM_HeLa_Curcumin_4h_R1 2 VVGSELIQK 9 0 P62191-2;P62191 P62191-2 PSMC1 26S protease regulatory subunit 4 0 0 ; ; 112.84 0.0026941 3422300 1042.22 713.58 1094.38 915.28 1198.51 1090.66 1042.68 681.88 1121.7 883.33 FALSE FALSE TRUE 959.7271873 775.2586755 1134.938686 911.4928139 1184.218551 864.4448217 1071.934795 889.782073 998.6523164 914.0256518 1.050000277 0.848180436 1.241692378 0.99722892 1.295607567 0.945755538 1.172762266 0.973476041 1.09258675 1 9.836090844 -6.751716452 24.99991832 1.01111365 1.104132798 0.151824089 0.121942225 298.9527841 768675.0912 0.016783877 0.023567089 1.77E-07 6.751716452 0.093019147 VVIIGAGKPAAVVLQTK ddPTM_HeLa_Curcumin_4h_R1 1 VVIIGAGKPAAVVLQTK 17 1 F5H6X6;Q14697;Q14697-2;E9PKU7 F5H6X6 GANAB Neutral alpha-glucosidase AB 0 0 122.63 0.00018535 1880200 912.12 534.96 677.11 609.51 805.97 1232.8 565.98 420.32 785.66 735.24 FALSE FALSE TRUE 839.9247395 581.1995587 702.2042922 606.9880091 796.3593341 977.1033835 581.8598755 548.4736331 699.4750636 760.7895353 1.104017209 0.76394263 0.922994152 0.797839588 1.046753796 1.284328107 0.764810567 0.720926889 0.919406789 1 9.571353592 -7.290577312 24.93012788 1.049119238 0.912365863 0.0624889 0.165029691 1055.249543 902858.2731 0.028359473 0.032433222 5.12E-08 7.290577312 -0.136753374 GGS(ph)REYDTGGGSSSSR ddPTM_HeLa_Curcumin_4h_R1 1 GGSREYDTGGGSSSSR 16 1 A0A494C001;A0A499FJY3;A0A087WWP4;Q96T37-4;Q96T37-2;Q96T37-3;Q96T37 A0A494C001 RBM15 Putative RNA-binding protein 15 1 0 GGS(0.997)REYDT(0.003)GGGSSSSR 105.5 0.0188 23029000 4085.6 3418 3323.5 3841.7 3344.4 4052.7 3122 975 4772.1 4421.4 TRUE FALSE FALSE 3762.220449 3713.43669 3446.671834 3825.804063 3304.520214 3212.124337 3209.594918 1272.273012 4248.612569 4575.043321 0.822335481 0.811672465 0.753363759 0.836233407 0.722292661 0.702097032 0.701544159 0.278089828 0.928649692 1 12.15956969 -3.881761357 0.26654351 0.963084154 2.01E-29 0.752219547 0.091608544 4.333719178 0.201761254 0.053450507 1.415904589 0.000131292 3.881761357 -0.963084154 down VVINVPIFK ddPTM_HeLa_Curcumin_4h_R1 1 VVINVPIFK 9 0 A0A0C4DGB2;E1CEI4;P48506;B4E2I4;A0A2R8YEL6 A0A0C4DGB2 GCLC Glutamate--cysteine ligase catalytic subunit 0 0 154.31 6.05E-08 639170 1002.3 715.25 788.65 912.24 964.43 1362.4 830.36 1126.7 1064 1128.5 FALSE FALSE TRUE 922.9668974 777.0730229 817.8780628 908.4653926 952.9298021 1079.822883 853.6576668 1470.225643 947.281862 1167.715291 0.790404052 0.665464458 0.700408797 0.777985353 0.816063478 0.924731303 0.731049489 1.259061738 0.811226734 1 10.18947285 -4.251035874 24.80327795 0.84931725 1.259061993 0.605272614 0.104628453 926.6696967 2209251.078 0.018185433 0.337952343 5.61E-05 4.251035874 0.409744743 VVKPKS(ph)PEPEATLTFPFLDK ddPTM_HeLa_Curcumin_4h_R1 2 VVKPKSPEPEATLTFPFLDK 20 2 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;E7EPK0;E9PDJ9;Q9UPQ0-5;Q9UPQ0-9;Q9UPQ0-4 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 VVKPKS(0.99)PEPEAT(0.007)LT(0.003)FPFLDK;VVKPKS(0.95)PEPEAT(0.025)LT(0.025)FPFLDK ; 49.306 0.011779 577010000 13682 10368.3 11743.2 12339.3 10690.6 12024.6 11703.7 14882.7 14268.1 12554.2 TRUE FALSE FALSE 12599.05526 11264.48965 12178.41332 12288.24325 10563.12158 9530.562415 12032.07432 19420.36672 12702.92513 12990.45752 0.969870018 0.867135714 0.937489177 0.945943838 0.813144692 0.733658719 0.926224062 1.494971728 0.977865877 1 13.66516462 -4.260541912 24.79568742 0.940430346 1.494971921 0.810300099 0.083896231 25.77350144 711953.5464 0.013545432 0.109751367 5.49E-05 4.260541912 0.554541575 VVLASAS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 VVLASASPR 9 0 O95671;O95671-2 O95671 ASMTL N-acetylserotonin O-methyltransferase-like protein 1 0 VVLASAS(1)PR;VVLASAS(1)PR ; 117.53 0.006876 17647700 5605.9 3839 5565.5 4513.4 4823.2 6834.3 5035.6 4824.9 5649.8 4593.2 TRUE FALSE FALSE 5162.1871 4170.826054 5771.762326 4494.724747 4765.68649 5416.789142 5176.885383 6295.989799 5030.031075 4752.813358 1.08613293 0.877548883 1.214388593 0.945697718 1.002708529 1.139701632 1.089225474 1.324686943 1.058327078 1 12.21456603 VVLDDKDYFLFR ddPTM_HeLa_Curcumin_4h_R1 4 VVLDDKDYFLFR 12 1 P61604;B8ZZ54 P61604 HSPE1 "10 kDa heat shock protein, mitochondrial" 0 0 ;;; ;;; 166.86 0.00010663 942854060 8621.03 5938.58 8422.67 8072.22 8276.31 13443.36 10719.68 9615.65 8080.05 6443.61 FALSE FALSE TRUE 7938.666379 6451.884393 8734.82156 8038.819292 8177.620409 10655.0556 11020.44537 12547.41742 7193.68873 6667.524968 1.190646667 0.967658078 1.310054571 1.20566767 1.226485157 1.598052598 1.652854009 1.881870331 1.078914405 1 12.70293561 -2.629805155 0.355459165 1.054283519 4.504488177 0.894780099 0.09324603 3.947317982 0.141208089 0.028674935 7.496129843 0.002345281 2.629805155 3.450204658 VVLGDGVQLPPGDY(ph)ST(ph)TPGGTLFSTTPGGTR ddPTM_HeLa_Curcumin_4h_R1 1 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 31 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 0 VVLGDGVQLPPGDY(0.279)S(0.232)T(0.177)T(0.302)PGGT(0.252)LFS(0.239)T(0.238)T(0.238)PGGT(0.042)R 53.074 0.0021661 43346000 3628.7 2945 3339.8 3396.4 3698.9 4168.7 2931.1 2946.2 3449.6 3082.2 TRUE FALSE FALSE 3341.484566 3199.552677 3463.575926 3382.346597 3654.793033 3304.064629 3013.338777 3844.482817 3071.18751 3189.306221 1.047715188 1.003212754 1.085996667 1.060527388 1.145952374 1.035982248 0.944825792 1.205429191 0.962964136 1 11.63902691 -13.52287866 0.074906776 0.763360485 1.142554508 0.229374106 0.067024424 288.2818781 1.667915322 11.52399343 1.458214867 3.00E-14 13.52287866 0.379194023 VVLGDGVQLPPGDY(ph)STTPGGTLFSTT(ph)PGGTR ddPTM_HeLa_Curcumin_4h_R1 1 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 31 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 0 VVLGDGVQLPPGDY(0.544)S(0.084)T(0.157)T(0.233)PGGT(0.103)LFS(0.086)T(0.201)T(0.43)PGGT(0.162)R 74.575 4.01E-05 67972000 14958 12455 13816 13324 14163 16432 12184 11280 14219 12259 TRUE FALSE FALSE 13774.05852 13531.5547 14328.03311 13268.86882 13994.11548 13023.81797 12525.85025 14719.22007 12659.21127 12684.99934 1.085854098 1.066736729 1.129525728 1.046028341 1.103201908 1.026710182 0.987453757 1.160364276 0.997967043 1 13.63083582 -9.278163401 0.943814652 0.998828934 1.073172318 0.294510459 0.047141212 0.634799466 0.98893734 0.032742463 0.008328232 5.27E-10 9.278163401 0.074343384 VVLGDGVQLPPGDYS(ph)TTPGGT(ph)LFSTTPGGTRIIYDRK ddPTM_HeLa_Curcumin_4h_R1 1 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRK 37 2 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 0 VVLGDGVQLPPGDY(0.261)S(0.278)T(0.244)T(0.244)PGGT(0.249)LFS(0.249)T(0.22)T(0.22)PGGT(0.018)RIIY(0.017)DRK 50.261 0.0023163 9318100 1261.8 623.88 763.83 897.22 534.92 902.54 754.22 883.26 1430.9 1031.8 TRUE FALSE FALSE 1161.927199 677.8054072 792.1382117 893.5075414 528.5414284 715.3430303 775.3813833 1152.561908 1273.93385 1067.654973 1.0882984 0.634854353 0.741942136 0.836887912 0.495048908 0.670013299 0.726247152 1.079526567 1.193207433 1 10.06022978 -7.26712549 24.96720929 1.041696471 0.731680782 0.525964798 0.151075763 270.0243033 1185650.894 0.02401922 0.027868167 5.41E-08 7.26712549 -0.310015689 VVLGDGVQLPPGDYS(ph)TTPGGTLFST(ph)TPGGTRIIYDRK ddPTM_HeLa_Curcumin_4h_R1 1 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRK 37 2 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 0 VVLGDGVQLPPGDY(0.222)S(0.239)T(0.239)T(0.239)PGGT(0.081)LFS(0.081)T(0.408)T(0.408)PGGT(0.041)RIIY(0.041)DRK 56.728 0.00016886 44491000 1504.9 881.86 775.98 1235.4 620.15 1259.9 1098.2 894.59 1535.2 1249.9 TRUE FALSE FALSE 1385.785577 958.0840489 804.7385014 1230.288242 612.7551163 998.582538 1129.012536 1167.346373 1366.792401 1293.333932 1.071483198 0.740786293 0.622220203 0.951253355 0.47377951 0.772099543 0.872947433 0.902586984 1.056797759 1 10.3368791 -7.258800422 24.89892533 1.033755957 0.757666147 0.48610066 0.132019716 133.7879881 1262309.674 0.021514159 0.025720992 5.51E-08 7.258800422 -0.27608981 VVLGDGVQLPPGDYST(ph)TPGGTLFS(ph)TTPGGTRIIYDRK ddPTM_HeLa_Curcumin_4h_R1 1 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRK 37 2 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 0 VVLGDGVQLPPGDY(0.052)S(0.054)T(0.292)T(0.292)PGGT(0.292)LFS(0.308)T(0.308)T(0.308)PGGT(0.048)RIIY(0.045)DRK 63.516 4.93E-05 41679000 4094.4 2978.6 2878.2 3591.8 2398.3 4251.8 2620.6 2804.3 5138.9 4311.8 TRUE FALSE FALSE 3770.32392 3236.056912 2984.868624 3576.938083 2369.701839 3369.928752 2694.126983 3659.318161 4575.175527 4461.634729 0.845054369 0.725307451 0.669007842 0.801710203 0.531128607 0.755312561 0.603843019 0.820174304 1.02544825 1 12.12335669 -7.763472307 0.662142916 0.98064225 0.680577856 0.66889032 0.086082242 0.249144516 0.245707329 0.027496287 0.022595824 1.72E-08 7.763472307 -0.300064395 VVLGDGVQLPPGDYST(ph)TPGGTLFSTT(ph)PGGTR ddPTM_HeLa_Curcumin_4h_R1 1 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 31 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 0 VVLGDGVQLPPGDY(0.068)S(0.358)T(0.422)T(0.152)PGGT(0.013)LFS(0.137)T(0.276)T(0.559)PGGT(0.014)R 88.468 1.20E-06 70907000 17826 15819 16628 16997 17103 20167 16687 14783 16602 14874 TRUE FALSE FALSE 16415.05329 17186.32387 17244.24831 16926.67092 16899.0579 15984.13687 17155.19231 19290.26865 14780.80214 15390.87039 1.066544833 1.116657046 1.120420604 1.099786463 1.097992346 1.038546649 1.114634317 1.253357877 0.960361679 1 13.9097872 -1.000000003 0.042239979 0.708354655 1.744857168 0.595435103 0.048059572 357.433323 1.159575836 7.625451785 26.04407975 0.099999999 1.000000003 1.036502513 VVLGDGVQLPPGDYSTT(ph)PGGTLFSTT(ph)PGGTR ddPTM_HeLa_Curcumin_4h_R1 1 VVLGDGVQLPPGDYSTTPGGTLFSTTPGGTR 31 0 Q13541 Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 2 0 VVLGDGVQLPPGDY(0.067)S(0.087)T(0.097)T(0.749)PGGT(0.033)LFS(0.239)T(0.075)T(0.572)PGGT(0.081)R 75.965 4.87E-05 31459000 1808.4 1493.2 1902 1696.7 1844.5 1832.3 1487.6 1467.9 1704 1986.5 TRUE FALSE FALSE 1665.263232 1622.265554 1972.489793 1689.679505 1822.505542 1452.260326 1529.338052 1915.455953 1517.075463 2055.530727 0.810137844 0.789219802 0.95960122 0.822016175 0.886635027 0.706513557 0.744011282 0.931854692 0.738045626 1 11.00529522 -9.356309047 0.673032413 1.024854352 0.825385021 0 0.1107017 0.790955805 0.514675671 0.094997148 0.01573668 4.40E-10 9.356309047 -0.199469331 VVLIGGKPDR ddPTM_HeLa_Curcumin_4h_R1 4 VVLIGGKPDR 10 1 P61978-3;P61978;P61978-2;Q5T6W2 P61978-3 HNRNPK Heterogeneous nuclear ribonucleoprotein K 0 0 ;;; ;;; 136.57 0.00026739 98949000 21231.1 15986.4 18331.2 18091.8 18612.9 22732 18835.9 18839.7 20642.8 18247.3 FALSE FALSE TRUE 19550.63603 17368.19318 19010.5704 18016.94093 18390.95332 18017.12696 19364.38466 24583.8378 18378.33649 18881.39232 1.035444617 0.919857651 1.006841555 0.954216756 0.974025274 0.954226609 1.025580335 1.302014035 0.973357058 1 14.20467753 -4.265715771 4.308440486 0.998304147 1.323602065 0.87635889 0.03569479 0.057014268 2.475584419 0.005429293 0.056315218 5.42E-05 4.265715771 0.325297918 VVLPYLVPK ddPTM_HeLa_Curcumin_4h_R1 1 VVLPYLVPK 9 0 Q92616 Q92616 GCN1L1 Translational activator GCN1 0 0 99.919 0.0047334 0 249.09 299.84 321.64 416.28 230.23 346.31 295.66 203.14 629.16 324.86 FALSE FALSE TRUE 229.3742637 325.7568335 333.5602613 414.5575437 227.4846576 274.4814023 303.9554239 265.0764509 560.1427221 336.1488608 0.682359188 0.969085044 0.992299247 1.233255834 0.676737851 0.816547174 0.90422863 0.788568643 1.666353177 1 8.39295645 -4.249597457 20.87121496 0.879114194 0.788568097 0 0.294090904 702.5447063 1237966.63 0.024392316 0.436831046 5.63E-05 4.249597457 -0.090546097 VVNANQNAS(ph)PNVPGKR ddPTM_HeLa_Curcumin_4h_R1 2 VVNANQNASPNVPGKR 16 1 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 0 VVNANQNAS(1)PNVPGKR;VVNANQNAS(1)PNVPGKR ; 85.166 0.004256 36502000 5007.3 3643.8 3661.4 4493.4 3558.3 6570.5 5114.2 3274.9 6633.1 4334.7 TRUE FALSE FALSE 4610.966921 3958.753836 3797.094705 4474.807501 3515.869597 5207.704235 5257.690688 4273.401934 5905.465525 4485.330502 1.028010515 0.882600253 0.84655851 0.997653907 0.78385965 1.161052509 1.17219694 0.952750735 1.316617699 1 12.13099858 -5.157371458 21.29129637 0.976046296 1.103020617 0.11623052 0.145912803 11.7534381 2397.103481 0.014292337 0.036438663 6.96E-06 5.157371458 0.126974321 VVNGAAASQPPS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 VVNGAAASQPPSK 13 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 VVNGAAAS(0.058)QPPS(0.942)K 122.63 0.0022642 3912900 1487 1553.7 1638.3 2040.2 2018.3 2168.6 1758 746.52 1728.8 1697.2 TRUE FALSE FALSE 1369.302381 1687.994905 1699.016839 2031.758193 1994.233091 1718.807915 1807.324749 974.1305114 1539.154965 1756.177574 0.779706108 0.961175527 0.96745162 1.156920703 1.135553215 0.978721025 1.029124148 0.554687935 0.876423312 1 10.77822301 -7.018796191 21.55696121 0.89462856 0.987346844 0.046155537 0.162717996 300.7783018 344957.4798 0.028203928 0.034934837 9.58E-08 7.018796191 0.092718284 VVNGAAASQPPS(ph)KR ddPTM_HeLa_Curcumin_4h_R1 3 VVNGAAASQPPSKR 14 1 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 VVNGAAAS(0.013)QPPS(0.987)KR;VVNGAAAS(0.001)QPPS(0.999)KR;VVNGAAASQPPS(1)KR ;; 122.97 0.0007227 156337000 8737.5 8126.4 7638.2 8605.2 9296.5 12214.8 6971.9 3510.8 10019.5 9062.4 TRUE FALSE FALSE 8045.917655 8828.809805 7921.278411 8569.593962 9185.645309 9681.312791 7167.51275 4581.226758 8920.385918 9377.317725 0.858019094 0.941506949 0.844727527 0.913864093 0.979559996 1.032418126 0.764345729 0.488543408 0.951272654 1 13.1949596 -4.399663398 2.982506897 0.932960389 0.47261642 0.852411439 0.057731866 0.097199179 1.383797263 0.009632067 0.088271019 3.98E-05 4.399663398 -0.460343969 VVNIVPVIAK ddPTM_HeLa_Curcumin_4h_R1 1 VVNIVPVIAK 10 0 Q9UHD8;Q9UHD8-5;Q9UHD8-2;Q9UHD8-7;Q9UHD8-3;Q9UHD8-8;Q9UHD8-9;Q9UHD8-4;K7EL40;K7EK18 Q9UHD8 9-Sep Septin-9 0 0 89.698 0.013787 0 646.24 722.14 578.83 648.56 591.94 657.03 531.8 487.73 661.51 677.68 FALSE FALSE TRUE 595.0894221 784.5585638 600.281949 645.8764306 584.8815021 520.7545717 546.7208767 636.4366318 588.944008 701.2293296 0.848637382 1.11883307 0.856042273 0.921063058 0.834080204 0.742630905 0.779660596 0.907601272 0.839873609 1 9.453742529 -5.775844395 2.456892335 0.938039882 0.8039506 0.294633444 0.08722812 0.262961845 3.241330022 0.013324978 0.027915427 1.68E-06 5.775844395 -0.134089282 VVNTDHGS(ph)PEQLQIPVTDSGR ddPTM_HeLa_Curcumin_4h_R1 3 VVNTDHGSPEQLQIPVTDSGR 21 0 Q6IQ49-3;Q6IQ49-2;Q6IQ49 Q6IQ49-3 SDE2 Protein SDE2 homolog 1 0 VVNT(0.002)DHGS(0.998)PEQLQIPVTDSGR;VVNT(0.001)DHGS(0.999)PEQLQIPVTDSGR;VVNT(0.014)DHGS(0.986)PEQLQIPVTDSGR ;; 153.76 2.53E-06 159356600 7958.8 6935.9 6866.9 7502.8 7597.1 8976.7 5723 3907.54 8530.1 7351.6 TRUE FALSE FALSE 7328.852582 7535.40829 7121.393355 7471.755402 7506.509544 7114.831232 5883.571977 5098.930958 7594.369371 7607.067553 0.963426778 0.99057991 0.936154872 0.982212311 0.986780976 0.935292237 0.773434959 0.670288639 0.998330739 1 12.8931247 -4.651779286 2.027570215 0.97988599 0.664620843 0.970240284 0.018251192 0.047137394 0.336015427 0.002871983 0.020471041 2.23E-05 4.651779286 -0.315265147 VVPCLVTPVTGR ddPTM_HeLa_Curcumin_4h_R1 1 VVPCLVTPVTGR 12 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 112.75 0.0024711 3736100 457.94 323.54 484.35 392.03 369.57 308.05 452.55 265.5 337.46 366.08 FALSE FALSE TRUE 421.6935658 351.5053559 502.3004371 390.4078837 365.1631191 244.1569576 465.247335 346.4497278 300.4414823 378.8012528 1.113231709 0.927941377 1.326026336 1.030640424 0.963996598 0.644551611 1.2282096 0.91459499 0.79313751 1 8.565297292 -5.780463946 4.61470728 1.066183798 0.936347754 0.042645252 0.184280153 0.315551735 16.2901536 0.022996799 0.044271172 1.66E-06 5.780463946 -0.129836045 VVPEDGS(ph)PEK ddPTM_HeLa_Curcumin_4h_R1 1 VVPEDGSPEK 10 0 Q02040 Q02040 AKAP17A A-kinase anchor protein 17A 1 0 VVPEDGS(1)PEK 105.66 0.0094754 16660000 12024 10829 11196 11734 12258 12637 10090 7179.6 11694 11736 TRUE FALSE FALSE 11072.28771 11765.01051 11610.93361 11685.44782 12111.83136 10015.94375 10373.09824 9368.626989 10411.19746 12143.82513 0.911762776 0.968805989 0.956118314 0.962254289 0.997365429 0.824776678 0.854187057 0.771472488 0.857324389 1 13.5679353 -5.25050052 23.9206608 0.960625781 0.820549541 0.652316775 0.04427945 153.3155018 335262.3519 0.005322627 0.013411226 5.62E-06 5.25050052 -0.14007624 VVPEDGS(ph)PEKR ddPTM_HeLa_Curcumin_4h_R1 4 VVPEDGSPEKR 11 1 Q02040 Q02040 AKAP17A A-kinase anchor protein 17A 1 0 VVPEDGS(1)PEKR;VVPEDGS(1)PEKR;VVPEDGS(1)PEKR;VVPEDGS(1)PEKR ;;; 184.87 0.00014703 714826000 15729.4 14370.2 13485.4 15689.4 14065.1 15675.1 12582.2 10953.8 16158.5 14742.8 TRUE FALSE FALSE 14484.40139 15612.29606 13985.18079 15624.48142 13897.38287 12423.90757 12935.22267 14293.56319 14385.95298 15255.1112 0.949478585 1.02341411 0.916753775 1.024212883 0.910998464 0.814409505 0.847927131 0.936968797 0.943025114 1 13.89700508 -5.548479578 6.395395708 0.977394661 0.864059712 0.572162952 0.043032185 0.079950502 11.13316782 0.005834906 0.011944903 2.83E-06 5.548479578 -0.113334949 S(ph)LESVLSLGPRPTGGGS(ph)SPPEIR ddPTM_HeLa_Curcumin_4h_R1 1 SLESVLSLGPRPTGGGSSPPEIR 23 1 Q13470-2;Q13470 Q13470-2 TNK1 Non-receptor tyrosine-protein kinase TNK1 2 0 S(0.799)LES(0.197)VLS(0.006)LGPRPT(0.002)GGGS(0.54)S(0.456)PPEIR 76.001 0.00067524 28673000 2533.5 2406.1 2556.5 2334.3 2195.7 2669.8 2025.4 943.75 2725.6 2459.8 TRUE FALSE FALSE 2332.970802 2614.072563 2651.246139 2324.641285 2169.517712 2116.053385 2082.227273 1231.495031 2426.608499 2545.277867 0.916587863 1.027028364 1.041633282 0.913315326 0.852369692 0.831364392 0.818074639 0.483835202 0.953376655 1 11.31360745 -3.881589445 0.768870367 0.967219951 2.56E-15 0.87105055 0.054900996 1.163219958 0.330691703 0.009694657 1.10538919 0.000131344 3.881589445 -0.967219951 down VVPGQFDDADS(ph)SDSENR ddPTM_HeLa_Curcumin_4h_R1 1 VVPGQFDDADSSDSENR 17 0 E9PFQ8;Q9BRS2 E9PFQ8 RIOK1 Serine/threonine-protein kinase RIO1 1 0 VVPGQFDDADS(0.944)S(0.048)DS(0.009)ENR 103.67 0.0015907 5476700 1296.6 1165.7 1389.9 1533.3 1369.4 1721.8 1410.7 1139.4 1584.1 1364.8 TRUE FALSE FALSE 1193.972742 1266.457914 1441.410917 1526.955611 1353.070799 1364.679271 1450.280445 1486.797815 1410.328193 1412.226698 0.845454022 0.896780889 1.020665392 1.081239728 0.958111613 0.96633159 1.026945919 1.052803928 0.998655665 1 10.46375598 -6.753370562 24.93255632 0.922712876 1.015951076 0.34354118 0.054729662 164.2030527 507383.498 0.010731661 0.015022641 1.76E-07 6.753370562 0.0932382 VVPGQFDDADSS(ph)DSENR ddPTM_HeLa_Curcumin_4h_R1 2 VVPGQFDDADSSDSENR 17 0 E9PFQ8;Q9BRS2 E9PFQ8 RIOK1 Serine/threonine-protein kinase RIO1 1 0 VVPGQFDDADS(0.185)S(0.815)DSENR;VVPGQFDDADS(0.077)S(0.901)DS(0.022)ENR ; 313.59 5.27E-112 79025000 4048.8 3964 4350.3 3589.7 5218.3 4405.9 3787 1799.09 3670.41 3378.65 TRUE FALSE FALSE 3728.333208 4306.630497 4511.525945 3574.846773 5156.075181 3492.066675 3893.253028 2347.624259 3267.775206 3496.057836 1.066439225 1.231853333 1.290460901 1.022536508 1.474825481 0.998858383 1.113612306 0.671506128 0.934702845 1 11.77151334 -4.259695781 23.74013969 1.093514696 0.671505831 0.411346457 0.158878642 60.41203812 822393.5527 0.021532521 0.183833266 5.50E-05 4.259695781 -0.422008865 VVPGQFDDADSS(ph)DSENRDLK ddPTM_HeLa_Curcumin_4h_R1 4 VVPGQFDDADSSDSENRDLK 20 1 E9PFQ8;Q9BRS2 E9PFQ8 RIOK1 Serine/threonine-protein kinase RIO1 1 0 VVPGQFDDADS(0.233)S(0.767)DSENRDLK;VVPGQFDDADS(0.189)S(0.809)DS(0.001)ENRDLK;VVPGQFDDADS(0.252)S(0.745)DS(0.003)ENRDLK;VVPGQFDDADS(0.214)S(0.72)DS(0.065)ENRDLK ;;; 130.07 3.59E-05 453262000 12515.6 10976.3 11639.2 12131.7 10805.4 13103.5 11100.7 5974.9 13354 11390.9 TRUE FALSE FALSE 11524.97705 11925.04246 12070.55899 12081.50224 10676.55266 10385.68639 11412.15577 7796.619505 11889.09961 11786.73293 0.97779233 1.01173434 1.02408013 1.025008568 0.905811027 0.881133598 0.968220442 0.661474181 1.008684907 1 13.52487626 -3.619422026 0.972997984 0.990583742 1.10E-31 0.793782547 0.048012722 1.91586682 0.575546955 0.007071293 2.694263072 0.000240203 3.619422026 -0.990583742 VVPQQITHT(ph)SPR ddPTM_HeLa_Curcumin_4h_R1 1 VVPQQITHTSPR 12 0 H7BXF5;A0A2R8YDB8;Q9H0E3;Q9H0E3-3 H7BXF5 SAP130 Histone deacetylase complex subunit SAP130 1 0 VVPQQIT(0.008)HT(0.765)S(0.227)PR 162.64 0.00014571 21507000 4655.8 3547 3965 4115.9 3572.7 5260.3 4387.5 5522.4 4168.2 3996.2 TRUE FALSE FALSE 4287.288517 3853.586875 4111.946388 4098.869496 3530.097886 4169.254484 4510.601442 7206.154338 3710.958888 4135.067653 1.036812182 0.931928374 0.994408492 0.991246055 0.853697734 1.008267539 1.090816843 1.742693214 0.897436076 1 12.01369522 -4.25006587 3.126852413 0.996527511 1.866765017 0.93607048 0.060258102 0.061208941 0.887954324 0.00776855 0.132112727 5.62E-05 4.25006587 0.870237506 KAS(ph)SPSPLTIGTPESQR ddPTM_HeLa_Curcumin_4h_R1 1 KASSPSPLTIGTPESQR 17 1 Q9NPI6-2;Q9NPI6 Q9NPI6-2 DCP1A mRNA-decapping enzyme 1A 1 0 KAS(0.604)S(0.022)PS(0.354)PLT(0.019)IGT(0.001)PESQR 81.665 0.004015 66588000 1631.4 1525.7 1312.2 1557.3 1483.6 1409.3 1234.5 494.87 1679.4 1801.6 TRUE FALSE FALSE 1502.272969 1657.57471 1360.831286 1550.856305 1465.909039 1116.995294 1269.136748 645.7535849 1495.174022 1864.205466 0.805851606 0.889158808 0.729979238 0.831912755 0.78634521 0.599180356 0.680792311 0.346396144 0.802043578 1 10.86434516 -3.876046557 0.270716145 0.957706048 1.53E-28 0.709916929 0.091160311 3.834136835 0.182038595 0.046091526 1.265484218 0.000133031 3.876046557 -0.957706048 down VVPSFLPVDQGGS(ph)LVGR ddPTM_HeLa_Curcumin_4h_R1 2 VVPSFLPVDQGGSLVGR 17 0 Q14126 Q14126 DSG2 Desmoglein-2 1 0 VVPSFLPVDQGGS(1)LVGR;VVPSFLPVDQGGS(1)LVGR ; 236.68 3.64E-23 46668000 1260.23 813.71 938.11 1633.13 1360.7 2953.7 1337.19 643.46 1726.98 971.04 TRUE FALSE FALSE 1160.481466 884.0434666 972.8771818 1626.372541 1344.474541 2341.069325 1374.707953 839.6479919 1537.534615 1004.783568 1.154956652 0.879834718 0.968245514 1.618629716 1.338073775 2.329923976 1.368163251 0.835650601 1.530214729 1 9.97266906 -6.262048697 24.99753678 1.050302158 1.528193618 0.197677342 0.383655157 52.39348089 2149472.374 0.052891966 0.0838837 5.47E-07 6.262048697 0.477891459 VVPYLYTK(ac)NK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VVPYLYTKNKK 11 2 H0Y334;H0YBE5;Q8N7X0-2;Q8N7X0 H0Y334 ADGB Androglobin 0 2 ; VVPYLYTK(1)NK(1)K;VVPYLYTK(1)NK(1)K 80.24 0.0061876 19984700 12055 11161.4 10444.6 10003.8 9170.7 12153.3 8689.2 9139.2 10775.2 10829.1 FALSE TRUE FALSE 11100.83403 12126.14168 10831.68606 9962.406926 9061.345392 9632.568584 8932.995566 11925.70001 9593.187518 11205.41042 0.990667331 1.082168455 0.966647866 0.889071132 0.808658055 0.8596355 0.797203782 1.064280518 0.856121031 1 13.45190787 -6.314659914 3.627002197 1.00258595 0.872419507 0.214350994 0.086634223 0.166812555 4.483307413 0.010552537 0.01683763 4.85E-07 6.314659914 -0.130166442 SATDGNTSTTPPTSAK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 SATDGNTSTTPPTSAKK 17 1 A0A669KAX4;K4DI93;Q13620-1;Q13620;A0A669KAU9 A0A669KAX4 CUL4B Cullin-4B 0 1 ; SATDGNTSTTPPTSAK(1)K;SATDGNTSTTPPTSAK(1)K 360.25 3.76E-232 4011300 2315.4 2334.1 2320.67 2338.2 2502.9 3191.3 2950.7 3146.7 2712.8 1769.44 FALSE TRUE FALSE 2132.133647 2535.849203 2406.676072 2328.525148 2473.054552 2529.388407 3033.488701 4106.114344 2415.212627 1830.927908 1.164509884 1.385007674 1.314457036 1.271773256 1.350711047 1.381478973 1.65680401 2.242641191 1.319119456 1 10.83835927 -1 0.389186615 1.085204382 17.41170348 0.834332416 0.130247201 14.12415187 0.169425263 0.03095334 177.3028304 0.1 1 16.32649909 up VVS(ph)DADDS(ph)DSDAVSDK ddPTM_HeLa_Curcumin_4h_R1 2 VVSDADDSDSDAVSDK 16 0 Q96ST2-3;Q96ST2;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 2 0 VVS(1)DADDS(0.951)DS(0.045)DAVS(0.005)DK;VVS(1)DADDS(1)DSDAVSDK ; 244.1 6.50E-30 35874000 9672 7736.4 7682.7 7767.4 8106.4 9774.1 5883.1 5505.8 8347.1 7206.2 TRUE FALSE FALSE 8906.450994 8405.099943 7967.42762 7735.260557 8009.736474 7746.841483 6048.163952 7184.493074 7431.444013 7456.614914 1.194436228 1.127200484 1.068504638 1.03736892 1.074178641 1.038922027 0.811113893 0.963505982 0.996624353 1 12.86430512 -4.910760281 5.270749507 1.088454718 0.889129072 0.532794339 0.066406759 0.122537861 5.564336313 0.011238465 0.035095162 1.23E-05 4.910760281 -0.199325645 VVS(ph)ETNDTK ddPTM_HeLa_Curcumin_4h_R1 1 VVSETNDTK 9 0 P05783 P05783 KRT18 "Keratin, type I cytoskeletal 18" 1 0 VVS(0.674)ET(0.325)NDTK 116.84 0.0070544 42292000 2752 2312 2448.5 2874.8 2652.9 3631.2 2459.5 4791.9 3041 3011.3 TRUE FALSE FALSE 2534.176296 2511.838978 2539.243564 2862.904839 2621.2659 2878.048188 2528.506951 6252.928251 2707.409908 3115.942451 0.813293678 0.806124958 0.814919917 0.918792591 0.841243361 0.923652549 0.811474214 2.006753446 0.868889574 1 11.60545287 -4.259051714 24.99638155 0.888210698 2.006753837 0.966127269 0.063936031 35.45161854 371118.2807 0.011607707 0.104310548 5.51E-05 4.259051714 1.118543139 VVSDADDS(ph)DSDAVSDK ddPTM_HeLa_Curcumin_4h_R1 2 VVSDADDSDSDAVSDK 16 0 Q96ST2-3;Q96ST2;Q96ST2-2 Q96ST2-3 IWS1 Protein IWS1 homolog 1 0 VVSDADDS(0.84)DS(0.16)DAVSDK;VVSDADDS(0.985)DS(0.015)DAVSDK ; 255.72 2.96E-40 19784900 4742.3 3580 4036.3 4664.6 4714.7 4847.3 2979.1 2236.8 4894.1 3567.6 TRUE FALSE FALSE 4366.941951 3889.439248 4185.888829 4645.299121 4658.480282 3841.91534 3062.685528 2918.790023 4357.229474 3691.573834 1.18294856 1.053599202 1.133903591 1.258351947 1.261922554 1.040725585 0.829642225 0.790662778 1.180317575 1 11.8500203 -4.804230892 3.640607911 1.113805851 0.800244519 0.71263683 0.083571804 0.113856547 3.073414392 0.014368379 0.053098144 1.57E-05 4.804230892 -0.313561333 VVSISSEHLEPIT(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 1 VVSISSEHLEPITPTK 16 0 O00267-2;O00267 O00267-2 SUPT5H Transcription elongation factor SPT5 1 0 VVSISSEHLEPIT(0.921)PT(0.079)K 86.213 0.0079459 7644000 2057.5 2477.1 2031.8 1660.6 4344.7 7569.7 3154.3 2873.7 3175.4 2256.8 TRUE FALSE FALSE 1894.646704 2691.209486 2107.100295 1653.728877 4292.89229 5999.658892 3242.801169 3749.877901 2827.066564 2335.223632 0.81133416 1.152441869 0.902311996 0.708167241 1.838321706 2.569201001 1.388646948 1.605789634 1.2106192 1 11.189345 -5.752560529 24.94332073 0.915573583 1.868837845 0.652570957 0.315525441 77.59165666 217976.202 0.043204864 0.085386988 1.77E-06 5.752560529 0.953264262 VVSQSQPGS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 VVSQSQPGSR 10 0 Q7Z460-4 Q7Z460-4 CLASP1 CLIP-associating protein 1 1 0 VVSQSQPGS(1)R 127.78 0.0032342 59517000 2803.1 2458.5 2089.5 2033.4 2198.4 2765.5 1760.4 1600.5 2738.8 1965.3 TRUE FALSE FALSE 2581.231677 2671.001785 2166.938708 2024.98633 2172.185516 2191.904126 1809.792086 2088.485082 2438.360492 2033.594029 1.269295464 1.313439038 1.065570944 0.995767248 1.06815101 1.077847444 0.889947581 1.026992139 1.199039955 1 10.98981598 -6.530670131 24.98431894 1.146824893 1.013670009 0.424046624 0.09483429 224.2682193 719149.975 0.019863816 0.028121484 2.95E-07 6.530670131 -0.133154884 GPS(ph)LDIDTPDVNIEGPEGK ddPTM_HeLa_Curcumin_4h_R1 1 GPSLDIDTPDVNIEGPEGK 19 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GPS(0.998)LDIDT(0.002)PDVNIEGPEGK 252.79 2.46E-43 42689000 6935.5 5083.2 7185.5 7372.7 7876.8 8250.7 10146 11184 5523.5 4515.2 TRUE FALSE FALSE 6386.547857 5522.569158 7451.800951 7342.193721 7782.874305 6539.411815 10430.66945 14593.95012 4917.585869 4672.102864 1.366953606 1.18203073 1.594956526 1.57149659 1.665818269 1.399672055 2.232542767 3.123636303 1.052542295 1 12.18985632 -1 0.471928225 1.185280236 51.13512492 0.892868024 0.197799424 19.797284 0.203583914 0.045099229 972.8475876 0.1 1 49.94984469 up VVSSTS(ph)EEEEAFTEK ddPTM_HeLa_Curcumin_4h_R1 1 VVSSTSEEEEAFTEK 15 0 Q8N573-3;Q8N573-2;Q8N573-5;Q8N573-8;Q8N573 Q8N573-3 OXR1 Oxidation resistance protein 1 1 0 VVSS(0.001)T(0.011)S(0.987)EEEEAFTEK 222.45 9.01E-15 15059000 1750.4 1358.9 1547.5 1703.6 1765.6 2256.6 2022.5 2524.1 1729.8 1766.7 TRUE FALSE FALSE 1611.853993 1476.357261 1604.851711 1696.550955 1744.546373 1788.555723 2079.245907 3293.68647 1540.045268 1828.092693 0.881713492 0.807594312 0.877883117 0.928044273 0.954298641 0.978372557 1.137385382 1.80170649 0.842432812 1 10.83612351 -4.107528664 1.657370952 0.927135778 2.389164524 0.956040978 0.057636934 0.244581092 0.471728704 0.009508889 0.640117596 7.81E-05 4.107528664 1.462028746 EAQSSQATPVQTSQPDSS(ph)NIVKVSPR ddPTM_HeLa_Curcumin_4h_R1 1 EAQSSQATPVQTSQPDSSNIVKVSPR 26 1 H7C5E4;Q8IZH2-2;Q8IZH2 H7C5E4 XRN1 5-3 exoribonuclease 1 1 0 EAQSSQATPVQT(0.001)S(0.001)QPDS(0.374)S(0.439)NIVKVS(0.186)PR 65.423 0.00052916 8857700 1147.1 1120.8 974.55 972.24 1182.8 1288.7 661.09 448.25 1510.4 1276.1 TRUE FALSE FALSE 1056.305825 1217.676958 1010.66768 968.2171285 1168.695883 1021.409093 679.6384062 584.9193615 1344.712899 1320.44438 0.799962377 0.922172093 0.765399661 0.733250975 0.885077706 0.773534356 0.514704304 0.442971601 1.018379054 1 10.36680782 -3.875614085 0.376989655 0.922926131 4.26E-52 0.772114948 0.085791817 3.12360401 0.246567437 0.027847104 1.382437637 0.000133164 3.875614085 -0.922926131 down VVTDTDETELAR ddPTM_HeLa_Curcumin_4h_R1 2 VVTDTDETELAR 12 0 P05198 P05198 EIF2S1 Eukaryotic translation initiation factor 2 subunit 1 0 0 ; ; 242.35 6.67E-50 9669000 3056.9 2696.7 2951.8 3085.1 2752.1 3853.4 2820.4 2669.8 3130 2970.7 FALSE FALSE TRUE 2814.943139 2929.790732 3061.196305 3072.334674 2719.283005 3054.161403 2899.532833 3483.80973 2786.646831 3073.931604 0.915746836 0.953108627 0.995857 0.999480493 0.884627036 0.993568432 0.94326524 1.133340028 0.906541586 1 11.58586935 -4.257985213 24.88366437 0.960330084 1.133340097 0.633837275 0.040532192 162.0245783 1167159.555 0.005667223 0.055238297 5.52E-05 4.257985213 0.173010013 VVTS(ph)ENEAGK ddPTM_HeLa_Curcumin_4h_R1 4 VVTSENEAGK 10 0 P49321-4;P49321;P49321-3;E9PPR5 P49321-4 NASP Nuclear autoantigenic sperm protein 1 0 VVT(0.002)S(0.998)ENEAGK;VVT(0.003)S(0.997)ENEAGK;VVT(0.067)S(0.933)ENEAGK;VVT(0.07)S(0.93)ENEAGK ;;; 166.69 0.00054615 101971000 22823.2 19341.7 20907.1 20977.3 24018.1 23900.7 20089.8 18587.7 18890.4 19090.7 TRUE FALSE FALSE 21016.71964 21013.51036 21681.93552 20890.50149 23731.69984 18943.4254 20653.46572 24255.00416 16818.17038 19754.1004 1.063916818 1.063754356 1.097591643 1.057527352 1.201355635 0.958961685 1.045528032 1.227846557 0.851376172 1 14.26986453 -13.52287874 0.084937248 0.691993823 1.173386912 0.32210895 0.085183545 186.6105004 1.208794451 10.57040253 1.029834409 3.00E-14 13.52287874 0.481393089 VVTSENEAGK ddPTM_HeLa_Curcumin_4h_R1 1 VVTSENEAGK 10 0 P49321-4;P49321;P49321-3;E9PPR5 P49321-4 NASP Nuclear autoantigenic sperm protein 0 0 122.96 0.0024941 2963800 1616.5 2247.9 1734.8 1293.6 1382.5 2938.8 1443.9 1422.9 1980 1874.3 FALSE FALSE TRUE 1488.552319 2442.19846 1799.093214 1288.247426 1366.01459 2329.259753 1484.411948 1856.73566 1762.798954 1939.431785 0.767519812 1.259234008 0.927639336 0.664239617 0.704337528 1.201001123 0.765384975 0.957360642 0.908925473 1 10.92141832 -6.164605563 0.008384875 1.780967075 4.79E-05 0 0.190027919 20714.74764 65.12146096 6754.12101 7075.986339 6.85E-07 6.164605563 -1.780919197 VVTVGQFK ddPTM_HeLa_Curcumin_4h_R1 1 VVTVGQFK 8 0 F8VXU5;Q9UBQ0;Q9UBQ0-2 F8VXU5 VPS29 Vacuolar protein sorting-associated protein 29 0 0 92.47 0.016378 0 1284.4 814.23 1029.1 1265.7 1069.7 1365.9 851.12 1111.1 1086.2 1142 FALSE FALSE TRUE 1182.738385 884.6084131 1067.239351 1260.462869 1056.944526 1082.596943 875.0001365 1449.869275 967.0465775 1181.684415 1.000891921 0.748599543 0.903150907 1.066666237 0.894438915 0.916147264 0.740468543 1.226951339 0.818362809 1 10.20662908 -7.428443586 23.28808343 1.000448608 0.919986943 0 0.145413097 58.31688322 14374.50606 0.02099253 0.024005769 3.73E-08 7.428443586 -0.080461665 VVTVHLEK ddPTM_HeLa_Curcumin_4h_R1 2 VVTVHLEK 8 0 Q9Y266 Q9Y266 NUDC Nuclear migration protein nudC 0 0 ; ; 90.629 0.0065061 13120400 21759.9 17959 20440 17905.9 23928 27767 22604 20175.6 18708.3 17457.7 FALSE FALSE TRUE 20037.58095 19511.29594 21197.52438 17831.81013 23642.67423 22007.8112 23238.2074 26327.04756 16656.0463 18064.35378 1.109233201 1.080099304 1.173444932 0.987126933 1.308802658 1.218300498 1.286412329 1.457403231 0.922039421 1 14.14085803 -1 0.269863568 1.025261617 3.972829994 0.752183594 0.078851845 15.84196758 0.200884464 0.031418661 22.0292972 0.1 1 2.947568377 VVTVVTTK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 VVTVVTTKK 9 1 Q7L014;A0A0C4DG89;D6RJA6 Q7L014 DDX46 Probable ATP-dependent RNA helicase DDX46 0 1 ; VVTVVTTK(1)K;VVTVVTTK(1)K 196.88 1.05E-21 26455000 11204 9193.8 9341.4 7234.8 8670.5 14956.8 11352.9 10661.3 11429.9 9133.6 FALSE TRUE FALSE 10317.19158 9988.471105 9687.600502 7204.864315 8567.10995 11854.59108 11671.43182 13911.88129 10176.06857 9450.99192 1.091651719 1.056870135 1.025035317 0.762339485 0.906477333 1.254322423 1.234942524 1.472002242 1.076719635 1 13.20625004 -4.841552734 1.926659786 1.016158896 1.40616805 0.656338464 0.109443391 0.191113485 1.319653198 0.0167811 0.088237712 1.44E-05 4.841552734 0.390009154 VVVDPVVTEQPSTSS(ph)AAK ddPTM_HeLa_Curcumin_4h_R1 1 VVVDPVVTEQPSTSSAAK 18 0 Q8WWQ0 Q8WWQ0 PHIP PH-interacting protein 1 0 VVVDPVVTEQPS(0.001)T(0.001)S(0.207)S(0.791)AAK 211.49 6.80E-13 3002900 2350 1919.2 1774.5 2391.5 2526.5 4263.8 4425.9 1349.6 2569.9 1643.5 TRUE FALSE FALSE 2163.99502 2085.087096 1840.264531 2381.604607 2496.373138 3379.439817 4550.078842 1761.086827 2287.9884 1700.611503 1.272480527 1.226080791 1.082119301 1.400440138 1.467926763 1.987190967 2.675554549 1.035560929 1.345391582 1 10.73183789 -5.576773508 1.93969543 1.143977791 1.969300153 0.366994863 0.389406969 0.209929212 1.577082491 0.053616898 0.134324221 2.65E-06 5.576773508 0.825322362 VVVFIKPTCPYCR ddPTM_HeLa_Curcumin_4h_R1 1 VVVFIKPTCPYCR 13 1 P35754 P35754 GLRX Glutaredoxin-1 0 0 132.17 0.0005792 4512700 2151.1 1477.5 1465.4 1432.6 1396 2173.9 1508.2 1500.2 1739.3 1705.9 FALSE FALSE TRUE 1980.838165 1605.208516 1519.709013 1426.672281 1379.353612 1723.008635 1550.516033 1957.604074 1548.503142 1765.179898 1.122173534 0.909373893 0.860937185 0.808230528 0.781423816 0.976109368 0.878389809 1.109011085 0.877249477 1 10.78559951 -7.189525295 7.0961294 1.057593002 0.894594816 0.073285304 0.106978061 0.203880297 17.48530828 0.015885441 0.019467343 6.46E-08 7.189525295 -0.162998186 VVVISSSEDS(ph)DAENSSSR ddPTM_HeLa_Curcumin_4h_R1 1 VVVISSSEDSDAENSSSR 18 0 P29590;P29590-5;P29590-11;P29590-12 P29590 PML Protein PML 1 0 VVVISSSEDS(1)DAENSSSR 194.32 4.61E-09 5486600 1745 1496.3 1631.3 1814.9 2000.8 1940 1295.3 751.32 2022.5 1643.4 TRUE FALSE FALSE 1606.881409 1625.633505 1691.757413 1807.390425 1976.941767 1537.622132 1331.642632 980.3940093 1800.63681 1700.508028 0.944941972 0.955969321 0.994854117 1.062853215 1.162559503 0.904213392 0.783085178 0.576530068 1.058881688 1 10.7317501 -4.541033457 2.010419718 0.991647095 0.563169757 0.809902979 0.068031222 0.15048067 0.957086515 0.010120023 0.095570171 2.88E-05 4.541033457 -0.428477339 VVVS(ph)PTK ddPTM_HeLa_Curcumin_4h_R1 1 VVVSPTK 7 0 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 1 0 VVVS(0.988)PT(0.012)K 99.815 0.011919 43236000 12085 10425 10626 11367 12665 15294 11387 8803.4 12369 11414 TRUE FALSE FALSE 11128.4595 11326.09055 11019.80891 11319.96637 12513.97815 12121.852 11706.48857 11487.51613 11012.15165 11810.63565 0.942240522 0.958973834 0.933041136 0.958455303 1.059551621 1.026350517 0.991181924 0.972641649 0.9323928 1 13.52779899 -5.807938827 24.99999721 0.966744881 1.011908091 0.455479014 0.02932816 113.9284936 61252.16041 0.004900875 0.008883604 1.56E-06 5.807938827 0.04516321 VVVSPTK(ac)K ddPTM_HeLa_Curcumin_4h_R1 1 VVVSPTKK 8 1 P19338;C9JYW2;C9JLB1;C9J1H7;C9JWL1 P19338 NCL Nucleolin 0 1 VVVSPTK(1)K 95.741 0.0058343 7492900 8067 6608.3 7143.8 6596.4 7091.2 9196.7 9143.6 9182.6 7884.6 7020.5 FALSE TRUE FALSE 7428.488438 7179.492006 7408.555512 6569.105845 7006.642071 7289.200752 9400.144807 11982.33247 7019.679106 7264.461852 1.022579317 0.988303353 1.019835421 0.904279763 0.964509445 1.003405469 1.293990525 1.649445301 0.966304077 1 12.82664021 -4.433830868 2.097187008 0.997450776 1.715609137 0.969088912 0.037493586 0.060667952 0.379571486 0.00573625 0.071328444 3.68E-05 4.433830868 0.718158361 VVYENAYGQFIGPHR ddPTM_HeLa_Curcumin_4h_R1 1 VVYENAYGQFIGPHR 15 0 E2QRB9;E9PIR7;F8W809;A0A087WSW9;A0A182DWI3;A0A087WSY9;Q16881-7;Q16881-5;Q16881-2;Q16881-4;Q16881-3;Q16881-6;Q16881;E9PKD3 E2QRB9 TXNRD1 "Thioredoxin reductase 1, cytoplasmic" 0 0 123.76 0.00029925 1541500 482.12 480.04 493.61 565.05 551.35 712.15 398.73 607.61 560.97 577.85 FALSE FALSE TRUE 443.9596933 521.5325186 511.9036208 562.7119728 544.7755113 564.4420624 409.9172907 792.8674919 499.4329945 597.9302445 0.742494124 0.872229701 0.856125987 0.941099699 0.911102117 0.943993162 0.685560388 1.326020049 0.835269664 1 9.223833377 -4.245831267 24.98595534 0.875329636 1.326020382 0.699937734 0.090279346 1570.742495 2514454.212 0.014990738 0.497802451 5.68E-05 4.245831267 0.450690746 VWDYETGDFER ddPTM_HeLa_Curcumin_4h_R1 3 VWDYETGDFER 11 0 P43034 P43034 PAFAH1B1 Platelet-activating factor acetylhydrolase IB subunit alpha 0 0 ;; ;; 223.87 6.94E-11 49942000 8245.5 6745.4 7133.3 7596.8 7216.3 10753.9 8307.9 8831.5 8868.5 7066.1 FALSE FALSE TRUE 7592.859974 7328.442319 7397.666373 7565.366454 7130.250336 8523.419919 8540.997314 11524.18369 7895.647738 7311.646449 1.03846104 1.002297139 1.011764782 1.034700803 0.975190798 1.165731956 1.168135983 1.576140719 1.079872747 1 12.8359806 -2.577415239 0.86114007 1.01498603 11.01049705 0.938237192 0.042084889 4.420853022 0.218938856 0.005356422 76.40172821 0.002645969 2.577415239 9.995511015 VWEDRPSS(ph)AGSTPFPYNPLIMR ddPTM_HeLa_Curcumin_4h_R1 2 VWEDRPSSAGSTPFPYNPLIMR 22 1 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;Q9Y618-2 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 VWEDRPS(0.135)S(0.743)AGS(0.082)T(0.039)PFPYNPLIMR;VWEDRPS(0.164)S(0.821)AGS(0.011)T(0.003)PFPYNPLIMR ; 81.726 0.00033838 118331000 1187.71 864.91 996.08 959.5 941.34 1502.84 1491.36 750.85 1207.83 760.57 TRUE FALSE FALSE 1093.7015 939.6689664 1032.995601 955.5298432 930.1151353 1191.134044 1533.203548 979.7807085 1075.334071 786.9997509 1.389710097 1.193988899 1.312574241 1.214142498 1.181849339 1.513512606 1.948162685 1.244956822 1.366371552 1 9.620219369 -7.025821565 0.049147104 7.25E-12 2.620278467 0.141029977 0.225229346 37.25280567 1.382862457 35.01386028 37.82694359 9.42E-08 7.025821565 2.620278467 VWQVTIGTR ddPTM_HeLa_Curcumin_4h_R1 2 VWQVTIGTR 9 0 P63244;D6RHH4;D6RAC2;J3KPE3;H0YAF8;H0Y8R5;D6RHJ5;D6RF23 P63244 GNB2L1 "Guanine nucleotide-binding protein subunit beta-2-like 1;Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed" 0 0 ; ; 117.89 0.0015135 12164700 2114.6 1447.1 1750 1196.37 1541.2 2064.42 2059.47 1858.45 1656.53 1914.59 FALSE FALSE TRUE 1947.227179 1572.180876 1814.856539 1191.419738 1522.822197 1636.236021 2117.253185 2425.08285 1474.812803 1981.12186 0.982891168 0.793581106 0.916075167 0.601386397 0.768666596 0.825913869 1.068714261 1.22409575 0.744433158 1 10.95210191 -4.514202117 4.039562658 0.919579865 1.202704347 0.357461731 0.138262127 0.201013697 7.312793703 0.02113539 0.114148581 3.06E-05 4.514202117 0.283124483 VWS(ph)PLVTEEGK ddPTM_HeLa_Curcumin_4h_R1 2 VWSPLVTEEGK 11 0 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 0 VWS(1)PLVTEEGK;VWS(1)PLVTEEGK ; 152.96 0.00048023 39338000 8014.8 7535 8050.6 8084.2 9823.5 14199.1 13729.6 6320.8 7378 5887.7 TRUE FALSE FALSE 7380.420123 8186.291825 8348.962318 8050.749722 9706.361178 11254.0466 14114.81562 8247.982823 6568.651859 6092.297137 1.211434695 1.343711845 1.370412856 1.321463734 1.59321861 1.847258325 2.316829811 1.35383791 1.078189673 1 12.57277059 -6.032965822 0.53831978 1.063765019 1.955910674 0.578923332 0.240214745 0.499988227 0.256956901 0.057360031 0.204193562 9.27E-07 6.032965822 0.892145655 VWS(ph)PLVTEEGKR ddPTM_HeLa_Curcumin_4h_R1 1 VWSPLVTEEGKR 12 1 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 1 0 VWS(1)PLVTEEGKR 68.262 0.018466 83610000 1504 1531.5 1302.3 1492.5 1608.4 2326.4 2399.5 1167.5 1709.3 1099.5 TRUE FALSE FALSE 1384.956813 1663.876036 1350.564384 1486.32443 1589.22088 1843.878416 2466.823512 1523.465375 1521.794066 1137.707543 1.217322344 1.462481326 1.187092757 1.306420476 1.396862392 1.620696309 2.168240447 1.3390659 1.337596886 1 10.15191403 -5.433881172 0.288448185 1.00294231 2.051999536 0.33835576 0.243719446 2.326088321 0.25295506 0.134126221 0.825721031 3.68E-06 5.433881172 1.049057226 VWSPLVTEEGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 VWSPLVTEEGKR 12 1 O00151 O00151 PDLIM1 PDZ and LIM domain protein 1 0 1 VWSPLVTEEGK(1)R 82.029 0.013721 1055300 334.16 405.98 273.71 373.16 269.4 0 209.04 234.56 340.02 464.48 FALSE TRUE FALSE 307.7108834 441.0711022 283.8539334 371.6159628 266.187581 0 214.9050998 306.0762642 302.7206567 480.6206454 0.640236507 0.917711518 0.59059871 0.773200166 0.553841337 0 0.4471408 0.636835448 0.629853627 1 8.908754812 -7.298212053 0.120083246 1.371126708 1.39E-07 0.230449625 0.228217877 4.627590015 0.494522903 2.572228658 2.676975835 5.03E-08 7.298212053 -1.371126569 VWY(ph)LNEAS(ph)FDLY(ph)S(ph)YHYFW ddPTM_HeLa_Curcumin_4h_R1 1 VWYLNEASFDLYSYHYFW 18 0 A8MUL3 A8MUL3 ADARB2-AS1 Putative uncharacterized protein ADARB2-AS1 4 0 VWY(1)LNEAS(0.997)FDLY(0.38)S(0.864)Y(0.38)HY(0.38)FW 45.696 0.009354 0 843.6 464.48 709.2 929.35 704.78 683.94 569.59 870.33 848.17 918.24 TRUE FALSE FALSE 776.8281698 504.6275815 735.4835759 925.5045959 696.3759588 542.0831344 585.5711624 1135.68961 755.127873 950.1487717 0.817585828 0.531103756 0.774072017 0.974062824 0.73291255 0.570524481 0.616294185 1.195275566 0.794746987 1 9.892009614 -8.545391597 0.924422462 0.981263743 0.763790749 0.019583924 0.195730837 0.634403765 1.107987144 0.071093552 0.037873455 2.85E-09 8.545391597 -0.217472994 VWYVSNIDGTHIAK ddPTM_HeLa_Curcumin_4h_R1 1 VWYVSNIDGTHIAK 14 0 P06744-2;P06744;A0A2U3TZU2;K7EQ48;A0A0J9YXP8;A0A2R8Y6C7;A0A0J9YX90;A0A0J9YYH3;K7EPY4;K7ENA0 P06744-2 GPI Glucose-6-phosphate isomerase 0 0 83.877 0.012422 15320000 1580.7 1202.5 1392.3 1248.8 1600.7 2878.8 1830.1 1695.5 2125.1 1558.3 FALSE FALSE TRUE 1455.585927 1306.438742 1443.899863 1243.632796 1581.612698 2281.704429 1881.447681 2212.450145 1891.981847 1612.450809 0.902716485 0.810219285 0.895469093 0.771268673 0.980875007 1.415053666 1.166824854 1.372103963 1.17335787 1 10.65503943 -5.353154115 5.60695844 0.923294537 1.301507884 0.685307919 0.119515441 0.07749736 3.747181491 0.013663875 0.031064185 4.43E-06 5.353154115 0.378213347 VY(ph)PESQAREPGVT(ph)ASLR ddPTM_HeLa_Curcumin_4h_R1 1 VYPESQAREPGVTASLR 17 1 Q8N475-3;Q8N475-2;Q8N475 Q8N475-3 FSTL5 Follistatin-related protein 5 2 0 VY(1)PES(0.005)QAREPGVT(0.757)AS(0.238)LR 76.574 0.017583 82126000 3434.5 3032.7 3117.1 3126.2 3007.7 3746.4 3403.4 2554.5 3081.8 2688.9 TRUE FALSE FALSE 3162.655701 3294.833075 3232.622468 3113.264613 2971.835142 2969.354409 3498.890244 3333.355291 2743.73425 2782.339075 1.136689532 1.184195379 1.161836276 1.11893789 1.068106748 1.067215149 1.25753553 1.198040642 0.986125047 1 11.44208253 -9.051977127 0.609030686 0.985669546 1.150338963 0.557171254 0.055242109 0.691282734 0.41845688 0.061003186 0.01391751 8.87E-10 9.051977127 0.164669417 VY(ph)Y(ph)S(ph)PPVARR ddPTM_HeLa_Curcumin_4h_R1 1 VYYSPPVARR 10 1 O94964-2;H0YDM2;O94964;O94964-3 O94964-2 SOGA1 Protein SOGA1;N-terminal form;C-terminal 80 kDa form 3 0 VY(1)Y(1)S(1)PPVARR 69.628 0.0063533 0 920.44 829.18 760.59 755.97 684.77 895.53 806.81 585.82 535.7 785.36 TRUE FALSE FALSE 847.5862028 900.8506244 788.7781345 752.8419964 676.604565 709.7869833 829.4469172 764.4338212 476.9350503 812.6512015 1.042988925 1.108532939 0.97062323 0.926402367 0.83258914 0.873421441 1.020667804 0.940666574 0.586887769 1 9.666492455 -6.489336785 4.517625675 1.028055509 0.91869804 0 0.149247005 0.145177352 6.934502634 0.00893019 0.01346687 3.24E-07 6.489336785 -0.109357469 VYAILTHGIFSGPAISR ddPTM_HeLa_Curcumin_4h_R1 1 VYAILTHGIFSGPAISR 17 0 B7ZB02;H7C540;B1ALA9;A0A0B4J207;A0A2R8Y7H4;P60891-2;P60891;P21108;P11908;P11908-2 B7ZB02 PRPS1;PRPS2;PRPS1L1 Ribose-phosphate pyrophosphokinase 1;Ribose-phosphate pyrophosphokinase 3;Ribose-phosphate pyrophosphokinase 2 0 0 74.428 0.0084912 762770 1552.8 1316.2 1423.4 1402.3 1243.5 997.67 841.32 804.64 1511.1 1409.4 FALSE FALSE TRUE 1429.894241 1429.966463 1476.152456 1396.497654 1228.672075 790.7419959 864.9251749 1049.971032 1345.336111 1458.376545 0.980469856 0.980519378 1.012188835 0.957570018 0.84249303 0.542207017 0.593073975 0.719958803 0.922488856 1 10.51014755 -5.50054613 2.905958192 0.98940623 0.616749755 0.909295437 0.050138001 0.044081883 0.74646741 0.006422895 0.015013919 3.16E-06 5.50054613 -0.372656475 VYALPEDLVEVKPK ddPTM_HeLa_Curcumin_4h_R1 1 VYALPEDLVEVKPK 14 1 P13797;A0A0A0MSQ0;P13797-3;P13797-2 P13797 PLS3 Plastin-3 0 0 136.93 0.00061639 1237200 627.89 439.33 466.02 634.76 471.29 734.7 607.45 551.17 524.46 495.83 FALSE FALSE TRUE 578.191844 477.3037276 483.2911112 632.1335313 465.6701746 582.3149382 624.4934121 719.2191957 466.9280501 513.0600556 1.126947689 0.930307714 0.941977661 1.232084869 0.907632877 1.134983969 1.217193592 1.401822629 0.91008459 1 9.002983898 -4.473331863 1.618256023 1.046245428 1.45071882 0.576802272 0.104327013 0.366431885 1.228010855 0.013737371 0.203502941 3.36E-05 4.473331863 0.404473392 VYEDSGIPLPAES(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 VYEDSGIPLPAESPK 15 0 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 0 VYEDSGIPLPAES(1)PK;VYEDSGIPLPAES(1)PK ; 262.82 2.40E-50 177079000 18654.5 16829.9 20208 19552.9 20993 20182.4 20551 13801.3 17655.5 15342 TRUE FALSE FALSE 17177.97664 18284.60156 20956.92626 19471.99528 20742.67219 15996.34274 21127.60575 18009.25284 15718.73582 15875.13336 1.082068179 1.15177625 1.320110249 1.226572076 1.306614043 1.007635172 1.330861623 1.134431594 0.990148269 1 13.95448109 -7.339719396 1.759259973 1.030836578 1.220503697 0.470736827 0.093440635 0.216712113 1.27665476 0.01666732 0.019189777 4.57E-08 7.339719396 0.189667119 VYEDSGIPLPAES(ph)PKKGPK ddPTM_HeLa_Curcumin_4h_R1 2 VYEDSGIPLPAESPKKGPK 19 2 Q8IXM2-2;F8W038;F8W1H0;H0YIS7;Q8IXM2;Q8IXM2-3 Q8IXM2-2 BAP18;C17orf49;RNASEK-C17orf49 Chromatin complexes subunit BAP18 1 0 VYEDS(0.001)GIPLPAES(0.999)PKKGPK;VYEDSGIPLPAES(1)PKKGPK ; 68.458 0.003282 245990000 10100.5 7939.7 9120.9 9810.7 8820.5 11952.3 10168.6 7366.5 12090.3 10979.2 TRUE FALSE FALSE 9301.034767 8625.972289 9458.928578 9770.105923 8715.321298 9473.25825 10453.90355 9612.511939 10764.02434 11360.72638 0.818700711 0.759279997 0.832598925 0.859989546 0.767144723 0.83386026 0.92017915 0.846117723 0.94747677 1 13.47176746 -9.141827657 0.876367075 1.001116654 0.829936335 0.60581669 0.045686461 0.288856918 0.397108998 0.031681487 0.008961181 7.21E-10 9.141827657 -0.171180319 VYENYPTYDLTER ddPTM_HeLa_Curcumin_4h_R1 1 VYENYPTYDLTER 13 0 A0A494C198;B4DFG0;H0Y993;P35659;A0A494C028;P35659-2 A0A494C198 DEK Protein DEK 0 0 124.48 0.017832 5216200 1638.3 1603.9 1757.9 2108.1 1835.5 2124.7 1814 1597.4 1846.3 1445.3 FALSE FALSE TRUE 1508.626826 1742.533969 1823.04932 2099.377241 1813.612861 1684.01327 1864.895958 2084.439906 1643.765509 1495.524067 1.008761316 1.165166116 1.219003666 1.403773625 1.212693865 1.126035553 1.246984919 1.393785598 1.099123408 1 10.54643541 -7.063065769 2.136799627 1.002426848 1.264639666 0.601190819 0.083226796 0.126351454 1.128996699 0.01373605 0.017530614 8.65E-08 7.063065769 0.262212818 VYFQS(ph)PPGAAGEGPGGADDEGPVRR ddPTM_HeLa_Curcumin_4h_R1 1 VYFQSPPGAAGEGPGGADDEGPVRR 25 1 Q96C90 Q96C90 PPP1R14B Protein phosphatase 1 regulatory subunit 14B 1 0 VY(0.025)FQS(0.975)PPGAAGEGPGGADDEGPVRR 61.751 0.0018057 139520000 1517 1082.7 1057.3 984.14 1053.2 1327.1 1790.2 780.51 1427.1 1253.5 TRUE FALSE FALSE 1396.927849 1176.283764 1096.484468 980.0678894 1040.641278 1051.844501 1840.428194 1018.483906 1270.5507 1297.059032 1.076996355 0.906885296 0.845362039 0.755607775 0.802308339 0.810945743 1.418924003 0.785225561 0.979562741 1 10.34102843 -7.24929715 22.73851188 1.036359387 0.908035524 0.075188708 0.181674635 411.4689312 770548.1501 0.030101602 0.036681598 5.63E-08 7.24929715 -0.128323863 VYGPGVAK ddPTM_HeLa_Curcumin_4h_R1 2 VYGPGVAK 8 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 105.27 0.0091298 14796100 11576.1 9960.2 12520.7 9647.8 12787.1 12691.5 11096.4 10108.2 9320.4 9446.1 FALSE FALSE TRUE 10659.83947 10821.11531 12984.72816 9607.87996 12634.62218 10059.13984 11407.73512 13190.14365 8297.975438 9774.351272 1.09059304 1.107092942 1.328449101 0.982968556 1.292630256 1.029136314 1.167109182 1.349464868 0.848954085 1 13.25478524 -1.000013704 0.028385561 0.225243706 2.439554571 0.399014959 0.121108898 1126.274425 2.479095493 63.59618284 145.7582518 0.099996845 1.000013704 2.214310865 VYIASSSGSTAIK ddPTM_HeLa_Curcumin_4h_R1 1 VYIASSSGSTAIK 13 0 O75368 O75368 SH3BGRL SH3 domain-binding glutamic acid-rich-like protein 0 0 141.91 0.00048806 2188000 801.18 564.52 702.12 613.03 678.69 965.47 793.46 775.34 836.94 822.05 FALSE FALSE TRUE 737.7657576 613.3145933 728.1411848 610.4934443 670.597065 765.2206389 815.7223521 1011.737597 745.1297759 850.6161763 0.867330975 0.721023901 0.856016151 0.717707306 0.788366226 0.899607438 0.958978179 1.189417301 0.87598825 1 9.732364481 -4.263833373 2.315391326 0.88663122 1.262684432 0.547726145 0.089463932 0.472754099 2.962384868 0.015974274 0.357601557 5.45E-05 4.263833373 0.376053212 VYIVHGVQEDLR ddPTM_HeLa_Curcumin_4h_R1 1 VYIVHGVQEDLR 12 0 Q15024 Q15024 EXOSC7 Exosome complex component RRP42 0 0 88.338 0.013348 11101000 1686.2 1511.8 1684.7 1470.3 1561 2082.6 1623.9 1666.5 1619 1393.2 FALSE FALSE TRUE 1552.735491 1642.473256 1747.136464 1464.216288 1542.386095 1650.645284 1669.462263 2174.608178 1441.399751 1441.613596 1.077081608 1.139329748 1.211931178 1.015678745 1.069902572 1.144998416 1.158051136 1.508454265 0.999851662 1 10.49346881 -1.024580997 0.88992937 1.057478497 199.9999833 0.790638671 0.065399951 262.351351 0.608141502 0.011028262 105930.872 0.094497214 1.024580997 198.9425048 VYMFQYDSTHGK ddPTM_HeLa_Curcumin_4h_R1 2 VYMFQYDSTHGK 12 0 P04406-2 P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 ; ; 184.03 0.00021664 74212000 8044.7 6449.8 6425 5672.7 8881.9 1734.72 5763.8 6058.8 9418.7 6660.4 FALSE FALSE TRUE 7407.953506 7007.291972 6663.116152 5649.22787 8775.989143 1374.919518 5925.516716 7906.100229 8385.492174 6891.848404 1.074886311 1.016750741 0.966811189 0.819697059 1.273386852 0.199499385 0.859786282 1.14716688 1.21672615 1 12.75067525 VYQWDDPDPR ddPTM_HeLa_Curcumin_4h_R1 1 VYQWDDPDPR 10 0 P49327;A0A0U1RQF0 P49327 FASN Fatty acid synthase;[Acyl-carrier-protein] S-acetyltransferase;[Acyl-carrier-protein] S-malonyltransferase;3-oxoacyl-[acyl-carrier-protein] synthase;3-oxoacyl-[acyl-carrier-protein] reductase;3-hydroxyacyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase;Oleoyl-[acyl-carrier-protein] hydrolase 0 0 143.7 0.010742 17210000 3361 3205.8 3496.4 3633.4 3630 3693.5 2789.7 2965.7 4164.1 3463.6 FALSE FALSE TRUE 3094.973303 3482.895067 3625.97966 3618.365954 3586.714621 2927.426466 2867.971474 3869.928278 3707.308648 3583.959842 0.863562495 0.971800807 1.011724411 1.009600027 1.000768641 0.816813412 0.800224221 1.079791194 1.034416905 1 11.80733876 -5.275506222 24.42119094 0.952287148 0.889071059 0.093274543 0.08713884 1069.396914 1856560.164 0.012874812 0.028921718 5.30E-06 5.275506222 -0.063216089 VYREELK(ac)R ddPTM_HeLa_Curcumin_4h_R1 2 VYREELKR 8 2 P04083;Q5T3N1 P04083 ANXA1 Annexin A1;Annexin 0 1 ; VYREELK(1)R;VYREELK(1)R 99.139 0.0031873 15058000 3423 2981.5 3158.1 2471.04 4672.5 8079.7 5867.6 5458.5 6939.8 3352.3 FALSE TRUE FALSE 3152.065938 3239.207575 3275.141964 2460.815491 4616.783489 6403.879143 6032.229064 7122.771522 6178.521303 3468.792175 0.908692645 0.933814253 0.944173591 0.70941566 1.330948427 1.84614091 1.738999847 2.053386643 1.781173674 1 11.76021769 -5.427022949 2.915963272 0.93779046 1.873710023 0.610337907 0.288606988 0.043661437 0.713909213 0.015582816 0.037919207 3.74E-06 5.427022949 0.935919563 NFVFHTLS(ph)PVKAEAAK ddPTM_HeLa_Curcumin_4h_R1 1 NFVFHTLSPVKAEAAK 16 1 Q9HAW4-2;Q9HAW4-3;Q9HAW4;E7ESG2 Q9HAW4-2 CLSPN Claspin 1 0 NFVFHT(0.269)LS(0.731)PVKAEAAK 81.017 0.0052129 164830000 3617.3 2775.9 2940.3 3180.8 2822.2 3279.6 2603.1 1162.8 3753.5 3059.4 TRUE FALSE FALSE 3330.986888 3015.836427 3049.270105 3167.638692 2788.547108 2599.373991 2676.13598 1517.332367 3341.750441 3165.713922 1.05220717 0.95265602 0.963217201 1.000608005 0.880858845 0.821101987 0.84534991 0.479301796 1.05560721 1 11.62831517 -3.865444301 0.618767822 1.017575925 1.69E-16 0.883182216 0.055172524 1.116701837 0.208882456 0.009402984 0.90082855 0.000136319 3.865444301 -1.017575925 down VYSLDDIRR ddPTM_HeLa_Curcumin_4h_R1 1 VYSLDDIRR 9 1 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 0 0 101.72 0.01776 8982600 3424 2245.8 2229.5 2555 2484.6 3364.2 2320.4 2619.1 3056.9 2472.3 FALSE FALSE TRUE 3152.986787 2439.916945 2312.127231 2544.428087 2454.972768 2666.426998 2385.504179 3417.651533 2721.565718 2558.212241 1.232496169 0.953758608 0.903805867 0.994611802 0.959643898 1.04230093 0.932488767 1.335953084 1.063854544 1 11.32092025 -7.232906115 24.87366771 1.109789882 1.007713086 0.074266546 0.126494002 1155.646911 1007427.897 0.022571411 0.027641413 5.85E-08 7.232906115 -0.102076797 VYSS(ph)SEFLAVQPTPTFAER ddPTM_HeLa_Curcumin_4h_R1 1 VYSSSEFLAVQPTPTFAER 19 0 O60307;V9GYV0 O60307 MAST3 Microtubule-associated serine/threonine-protein kinase 3 1 0 VYS(0.178)S(0.813)S(0.009)EFLAVQPTPTFAER 134.08 0.00018043 5694400 688.69 716.39 818.91 787.26 601.92 708.34 455.39 313.01 779.67 816.77 TRUE FALSE FALSE 634.1794598 778.3115594 849.259525 784.0025267 594.7424971 561.4222994 468.1670178 408.4453081 694.1421516 845.1526967 0.750372639 0.920912354 1.004859274 0.92764601 0.70371011 0.664285048 0.553943707 0.483279897 0.821321584 1 9.723068211 -5.264511947 1.416057035 0.89518058 0.512110715 0.786829861 0.08016441 0.203607962 0.751172384 0.016317187 0.064023723 5.44E-06 5.264511947 -0.383069864 VYSTSVTGSR ddPTM_HeLa_Curcumin_4h_R1 2 VYSTSVTGSR 10 0 Q5T123;Q9H299 Q5T123 SH3BGRL3 SH3 domain-binding glutamic acid-rich-like protein 3 0 0 ; ; 120.12 0.0029244 9959800 1028.69 969.8 1025.39 896.06 840.8 1185.84 839.98 979.54 1391.96 749.51 FALSE FALSE TRUE 947.268101 1053.625191 1063.391855 892.3523411 830.7740091 939.8834168 863.5475781 1278.197237 1239.265471 775.5554167 1.22140608 1.358542753 1.371135876 1.150597781 1.071198771 1.211884279 1.113456962 1.648105615 1.597907053 1 9.599086061 -8.806217943 0.757133073 1.003034028 1.257003511 0 0.242345332 0.660303809 0.726160353 0.091513065 0.033114909 1.56E-09 8.806217943 0.253969482 GPSLDIDT(ph)PDVNIEGPEGK ddPTM_HeLa_Curcumin_4h_R1 2 GPSLDIDTPDVNIEGPEGK 19 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GPS(0.006)LDIDT(0.994)PDVNIEGPEGK;GPS(0.286)LDIDT(0.714)PDVNIEGPEGK ; 151.28 0.00014297 91719300 7636.97 5810.01 7689.56 8299.69 7968.29 9659.2 11282 12420.1 5795.81 4793.19 TRUE FALSE FALSE 7032.495766 6312.201375 7974.541858 8265.348082 7873.273346 7655.773038 11598.54256 16206.93131 5160.024143 4959.752996 1.417912499 1.272684624 1.607850606 1.666483813 1.58743255 1.543579498 2.338532295 3.267689203 1.040379258 1 12.27605256 -1 0.463036097 1.208314853 51.43404561 0.913657502 0.187984028 17.81097139 0.18688487 0.045793711 859.3458257 0.1 1 50.22573076 up VYTTMTQHS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 VYTTMTQHSR 10 0 Q8IVF2;Q8IVF2-3;Q8IVF2-2 Q8IVF2 AHNAK2 Protein AHNAK2 1 0 VYTT(0.003)MT(0.06)QHS(0.937)R 86.944 0.014122 4538100 998.44 941.37 955.4 1185.8 1067 1230.8 922.41 10447 0 979.01 TRUE FALSE FALSE 919.4124205 1022.737828 990.8079645 1180.893474 1054.276722 975.518206 948.2903421 13632.24221 0 1013.030525 0.907586097 1.009582439 0.978063287 1.165703742 1.040715651 0.962970199 0.936092565 13.45689185 0 1 9.984461931 -4.261318355 25 0.97954936 13.45689552 0.992965439 0.317265902 0.130742275 26975.81648 0.010680563 0.082722759 5.48E-05 4.261318355 12.47734616 VYTY(ph)IQSR ddPTM_HeLa_Curcumin_4h_R1 1 VYTYIQSR 8 0 A0A0A0MTH5;Q9NR20-5;Q9NR20-2;Q9NR20;Q92630-2;Q92630;Q9NR20-3;Q9NR20-4 A0A0A0MTH5 DYRK4;DYRK2 Dual specificity tyrosine-phosphorylation-regulated kinase 4;Dual specificity tyrosine-phosphorylation-regulated kinase 2 1 0 VYTY(1)IQSR 154.12 0.0093972 18501000 1143.7 882.26 830.99 950.1 818.81 936.6 686.7 653.71 1196.5 1158.6 TRUE FALSE FALSE 1053.174938 958.5186231 861.7872204 946.1687379 809.0462255 742.3386023 705.9669538 853.0231697 1065.246943 1198.861264 0.878479412 0.799524225 0.718838156 0.789222879 0.674845581 0.619203093 0.588864596 0.711527844 0.888548972 1 10.227449 -6.963855659 0.421646343 0.997518028 0.607764361 0.810988731 0.053336342 0.211453483 0.092160797 0.020042211 0.03083852 1.09E-07 6.963855659 -0.389753667 VYVGNLGNNGNKTELER ddPTM_HeLa_Curcumin_4h_R1 2 VYVGNLGNNGNKTELER 17 1 P84103;P84103-2;A0A087X2D0 P84103 SRSF3 Serine/arginine-rich splicing factor 3 0 0 ; ; 153.41 0.0002496 10723400 2957.2 2670.9 3055.5 3526.2 2854.7 4295.4 3258.3 3132.7 4370.3 4119.6 FALSE FALSE TRUE 2723.1345 2901.760695 3168.739518 3511.609519 2820.659567 3404.485621 3349.719129 4087.845809 3890.889024 4262.755793 0.638820198 0.680724122 0.743354692 0.823788575 0.661698606 0.798658376 0.785810703 0.958967862 0.912763764 1 12.05757069 -9.480363159 1.234264931 0.999358514 0.746395025 0.402400823 0.091890032 0.303445729 0.830410763 0.064275776 0.01590831 3.31E-10 9.480363159 -0.25296349 VYVGNLGTGAGK ddPTM_HeLa_Curcumin_4h_R1 2 VYVGNLGTGAGK 12 0 Q16629-4;Q16629;A0A0B4J1Z1;C9JAB2;Q16629-3;Q16629-2 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 0 0 ; ; 147.62 6.76E-05 6583300 3710.7 3636.4 3511 3228.4 3701.3 4647.9 3911.3 3630.3 3183.9 2900.5 FALSE FALSE TRUE 3416.994179 3950.714213 3641.120749 3215.041736 3657.164415 3683.873147 4021.040551 4737.161758 2834.634136 3001.292159 1.138507682 1.316337765 1.213184374 1.071219184 1.21852996 1.227429038 1.339769785 1.578374083 0.944471243 1 11.55136805 -1 0.226725754 1.0296511 3.562518974 0.711923482 0.093418144 20.96152057 0.253651365 0.065821631 19.81209692 0.1 1 2.532867874 WADPQISESNFS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 WADPQISESNFSPK 14 0 D6RAW2;Q9BW91-2;Q9BW91 D6RAW2 NUDT9 "ADP-ribose pyrophosphatase, mitochondrial" 1 0 WADPQIS(0.046)ES(0.172)NFS(0.782)PK 92.8 0.0084565 17328000 3574.8 3108.5 3312 3247.6 4522.2 6709.6 5477.6 3418.2 4148.6 3632.8 TRUE FALSE FALSE 3291.850808 3377.184889 3434.745634 3234.162292 4468.275719 5317.953327 5631.286714 4460.393445 3693.508959 3759.03953 0.875715933 0.898416966 0.913729586 0.860369322 1.188674842 1.414710669 1.498065309 1.186577957 0.982567204 1 11.87614837 -5.558151689 3.535231941 0.92936139 1.37473537 0.850758169 0.084322276 0.062946725 1.650068175 0.012668168 0.027612846 2.77E-06 5.558151689 0.44537398 WAEYHADIYDK ddPTM_HeLa_Curcumin_4h_R1 2 WAEYHADIYDK 11 0 Q9NRX4-2;Q9NRX4 Q9NRX4-2 PHPT1 14 kDa phosphohistidine phosphatase 0 0 ; ; 108.56 0.005782 15912100 9893.4 8127.4 8861.2 9134.7 10792.9 11639.7 9064.1 9733.3 8693.9 8116.5 FALSE FALSE TRUE 9110.326951 8829.896241 9189.603867 9096.903032 10664.20172 9225.495014 9318.414251 12700.93836 7740.200921 8398.547771 1.084750269 1.051359888 1.094189629 1.083151907 1.269767346 1.098463123 1.10952685 1.512277921 0.921611823 1 13.03592417 -1 0.730429259 1.0551443 65.070545 0.692662247 0.085625966 128.4026269 0.563677936 0.01282613 13504.21264 0.1 1 64.0154007 WAHDKFS(ph)GEEGEIEDDESGTENR ddPTM_HeLa_Curcumin_4h_R1 2 WAHDKFSGEEGEIEDDESGTENR 23 1 Q9Y2W1 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 WAHDKFS(1)GEEGEIEDDESGTENR;WAHDKFS(1)GEEGEIEDDESGTENR ; 89.917 7.73E-05 39613000 5959.8 5557.4 5824.8 5654.7 6553.5 5993.5 4922 3825 4816.1 4982.1 TRUE FALSE FALSE 5488.075541 6037.756893 6040.672212 5631.30235 6475.353793 4750.380539 5060.098073 4991.224892 4287.785879 5155.227604 1.064565129 1.17119114 1.171756647 1.092347959 1.256075248 0.921468634 0.981546977 0.968187105 0.831735514 1 12.33182041 WAHDKFSGEEGEIEDDES(ph)GTENREEKDNIQPTTE ddPTM_HeLa_Curcumin_4h_R1 1 WAHDKFSGEEGEIEDDESGTENREEKDNIQPTTE 34 3 Q9Y2W1 Q9Y2W1 THRAP3 Thyroid hormone receptor-associated protein 3 1 0 WAHDKFSGEEGEIEDDES(0.819)GT(0.17)ENREEKDNIQPT(0.01)T(0.001)E 62.848 0.00016656 15297000 1298.6 1264.1 1288.3 1134.8 1023.3 1639.9 1093.6 1037.4 1581.4 1203.1 TRUE FALSE FALSE 1195.81444 1373.363171 1336.045531 1130.104498 1011.097816 1299.766255 1124.283473 1353.698484 1407.924376 1244.907635 0.960564789 1.103184792 1.07320856 0.907781803 0.812187015 1.044066417 0.903105934 1.087388691 1.130946856 1 10.28182299 -6.230937096 24.98273822 0.998239358 0.945719392 0.11198169 0.093003267 1408.239719 1153412.039 0.012454018 0.020651089 5.88E-07 6.230937096 -0.052519966 WAPHSPTASQPQS(ph)PGDPT(ph)S(ph)LEEHGGEEPPEEQPHR ddPTM_HeLa_Curcumin_4h_R1 1 WAPHSPTASQPQSPGDPTSLEEHGGEEPPEEQPHR 35 0 Q9Y4B5-4 Q9Y4B5-4 MTCL1 Microtubule cross-linking factor 1 3 0 WAPHS(0.224)PT(0.401)AS(0.554)QPQS(0.681)PGDPT(0.517)S(0.624)LEEHGGEEPPEEQPHR 49.808 0.0027658 3916600 427.44 469.83 262.57 323.48 363.12 456.15 410.86 313.36 323.83 419.52 TRUE FALSE FALSE 393.607673 510.4400117 272.3010752 322.1415255 358.7900312 361.5393481 422.3876258 408.9020215 288.3066592 434.0982888 0.906724774 1.175862759 0.627279771 0.742093516 0.826517958 0.832851355 0.973023015 0.94195723 0.664150647 1 8.761877925 -6.760375902 24.99999892 0.971215843 0.827529773 0.10323188 0.149280888 30.19116097 709714.8187 0.018805453 0.025740156 1.74E-07 6.760375902 -0.14368607 WASLADSYS(ph)DPGLTEDGLGR ddPTM_HeLa_Curcumin_4h_R1 2 WASLADSYSDPGLTEDGLGR 20 0 J3KQR7;Q9Y4F5-3;Q9Y4F5-2;Q9Y4F5 J3KQR7 CEP170B Centrosomal protein of 170 kDa protein B 1 0 WASLADS(0.005)YS(0.995)DPGLTEDGLGR;WAS(0.001)LADS(0.034)YS(0.964)DPGLT(0.001)EDGLGR ; 251 1.35E-43 8255500 2743.3 2728.39 2758.7 2591.89 2790.5 3515.1 1748.65 1163.7 3258.8 2656.23 TRUE FALSE FALSE 2526.16491 2964.219874 2860.939849 2581.165446 2757.22511 2786.028637 1797.712413 1518.506773 2901.317793 2748.533795 0.919095452 1.078473141 1.040896733 0.939106316 1.003162164 1.013641761 0.654062328 0.552478844 1.055587455 1 11.4244465 -4.686902219 4.430745622 0.979308303 0.578398061 0.898465165 0.05389155 0.046176708 1.677632879 0.007687614 0.031020555 2.06E-05 4.686902219 -0.400910242 WDAADDIHR ddPTM_HeLa_Curcumin_4h_R1 2 WDAADDIHR 9 0 Q9HD15;R4GMW4 Q9HD15 SRA1 Steroid receptor RNA activator 1 0 0 ; ; 117.7 0.005453 6311900 5565 4470.5 4730.5 4891.7 4829.7 6274.1 4477.9 4855.3 5204 4773.3 FALSE FALSE TRUE 5124.524378 4856.9101 4905.816491 4871.459442 4772.108982 4972.780936 4603.537822 6335.658619 4633.13422 4939.17182 1.037527052 0.983345038 0.993246777 0.986290743 0.966175941 1.006804606 0.932046503 1.282737036 0.938038681 1 12.27005344 -4.252330997 24.99541368 1.003584648 1.282737181 0.85759357 0.03578309 309.5535713 849466.0001 0.004466056 0.074310634 5.59E-05 4.252330997 0.279152533 WDAWNSLGKMS(ph)REEAMSAYIT(ph)EMK ddPTM_HeLa_Curcumin_4h_R1 1 WDAWNSLGKMSREEAMSAYITEMK 24 2 K7EM05;Q8NC06;Q8NC06-2;Q8NC06-3 K7EM05 ACBD4 Acyl-CoA-binding domain-containing protein 4 2 0 WDAWNS(0.117)LGKMS(0.708)REEAMS(0.194)AY(0.172)IT(0.81)EMK 43.497 0.0081749 0 125.91 0 0 59.529 203.93 246.27 175.53 89.715 0 150.92 TRUE FALSE FALSE 115.9440906 0 0 59.28268477 201.4982679 195.190826 180.4548994 117.0686905 0 156.1644588 0.742448644 0 0 0.379617009 1.290295305 1.249905564 1.155543975 0.749650026 0 1 7.28692234 -3.94455087 15.95199469 0.797018617 0.387368128 0 0.51971996 338841772 2336244170 0.068960394 4402012534 0.000113619 3.94455087 -0.409650489 WDDPYYDIAR ddPTM_HeLa_Curcumin_4h_R1 1 WDDPYYDIAR 10 0 E9PNR6;H0YE29;Q07960 E9PNR6 ARHGAP1 Rho GTPase-activating protein 1 0 0 152.11 0.0056227 11850000 4922.3 3955.3 4529 4178.6 4744.4 4764.4 4014.8 4143.7 5070.3 4524.5 FALSE FALSE TRUE 4532.694761 4297.178508 4696.848724 4161.31006 4687.826129 3776.209734 4127.444483 5407.095055 4514.100775 4681.726038 0.96816745 0.917862018 1.003230152 0.888841001 1.001302958 0.806584944 0.881607435 1.154936237 0.964195841 1 12.1928248 -7.98813115 0.743287028 0.995850464 0.942418167 0.007077108 0.08899321 1.352268113 1.646294791 0.02946232 0.021266944 1.03E-08 7.98813115 -0.053432297 WDEQTSNTKGDDDEES(ph)DEEAVKK ddPTM_HeLa_Curcumin_4h_R1 1 WDEQTSNTKGDDDEESDEEAVKK 23 2 O43395 O43395 PRPF3 U4/U6 small nuclear ribonucleoprotein Prp3 1 0 WDEQTSNTKGDDDEES(1)DEEAVKK 108.88 1.22E-05 61779000 1803 1284.8 1744.1 2151.4 1947.7 2110.1 1905.5 1378.9 1775 1568.8 TRUE FALSE FALSE 1660.290647 1395.852387 1808.73788 2142.498077 1924.47495 1672.441474 1958.963202 1799.320262 1580.286941 1623.315683 1.022777433 0.859877349 1.114224361 1.319828361 1.185521072 1.030262623 1.206766633 1.108422891 0.9734933 1 10.66472787 -6.535441469 24.76301791 0.999136353 1.170450396 0.571443418 0.082443967 122.9792111 242409.7787 0.01262843 0.017865805 2.91E-07 6.535441469 0.171314042 WDGERLYQEAR ddPTM_HeLa_Curcumin_4h_R1 1 WDGERLYQEAR 11 1 P05164-2;P05164;P05164-3 P05164-2 MPO Myeloperoxidase;Myeloperoxidase;89 kDa myeloperoxidase;84 kDa myeloperoxidase;Myeloperoxidase light chain;Myeloperoxidase heavy chain 0 0 88.134 0.016747 5455400 60.381 159.04 112.65 109.14 110.03 0 173.4 0 52.524 0 FALSE FALSE TRUE 55.60178014 172.7867089 116.8249081 108.6884076 108.7179641 0 178.2651373 0 46.76224861 0 0 WDGS(ph)EEDEDNSK ddPTM_HeLa_Curcumin_4h_R1 7 WDGSEEDEDNSK 12 0 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 0 WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK;WDGS(1)EEDEDNSK ;;;;;; 258.23 1.65E-52 1697797000 17639.63 18912.3 16463.51 17673.5 16282.5 18580.3 14679.54 13836.1 19861.3 17339.3 TRUE FALSE FALSE 16243.43467 20546.99494 17073.66216 17600.37174 16088.34182 14726.53634 15091.40838 18054.6632 17682.56508 17941.83938 0.905338317 1.145200027 0.951611582 0.98096808 0.896694117 0.820793009 0.841129388 1.006288308 0.985549179 1 14.13104018 -5.699663165 5.2219476 0.971395953 0.880983287 0.279959072 0.075548566 0.237091459 12.73390297 0.01144208 0.02300787 2.00E-06 5.699663165 -0.090412666 WDGS(ph)EEDEDNSKK ddPTM_HeLa_Curcumin_4h_R1 5 WDGSEEDEDNSKK 13 1 A0A087WUT6;O60841 A0A087WUT6 EIF5B Eukaryotic translation initiation factor 5B 1 0 WDGS(1)EEDEDNSKK;WDGS(1)EEDEDNSKK;WDGS(1)EEDEDNSKK;WDGS(0.997)EEDEDNS(0.003)KK;WDGS(0.848)EEDEDNS(0.152)KK ;;;; 236.42 3.69E-20 1053290000 18617.7 13557.75 16317.26 15590.8 15216.4 17655 14346.6 13577.98 18255.2 14981.1 TRUE FALSE FALSE 17144.0894 14729.6215 16921.99201 15526.2894 15034.95437 13993.15399 14749.12698 17717.8436 16252.65023 15501.69211 1.105949549 0.95019443 1.091622249 1.001586749 0.969891175 0.902685583 0.951452711 1.142961908 1.048443623 1 13.92013808 -6.020470715 17.94668343 1.045129358 0.982911658 0.086938608 0.070804288 31.59574094 27701.8266 0.011048277 0.018571394 9.54E-07 6.020470715 -0.0622177 WDKDDFES(ph)EEEDVK ddPTM_HeLa_Curcumin_4h_R1 1 WDKDDFESEEEDVK 14 1 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;Q7Z6E9-4 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 0 WDKDDFES(1)EEEDVK 64.346 0.018396 65445000 6343.6 5266 5992.2 5893.2 6439.3 5547.9 5624.3 4789.9 4744.3 5008.9 TRUE FALSE FALSE 5841.497366 5721.169575 6214.276203 5868.8155 6362.515553 4397.203002 5782.102721 6250.31846 4223.86216 5182.958902 1.1270584 1.103842358 1.198982342 1.13232916 1.22758364 0.84839627 1.115598798 1.205936334 0.814951891 1 12.33956024 -9.175764348 0.862964452 0.998035351 1.117084213 0.279147426 0.116664598 0.93320339 1.221534751 0.071673999 0.019138712 6.67E-10 9.175764348 0.119048862 WDKDDFESEEEDVKS(ph)TQPISSVGKPASVIK ddPTM_HeLa_Curcumin_4h_R1 1 WDKDDFESEEEDVKSTQPISSVGKPASVIK 30 3 A0A2R8Y880;Q7Z6E9-2;Q7Z6E9;Q7Z6E9-4 A0A2R8Y880 RBBP6 E3 ubiquitin-protein ligase RBBP6 1 0 WDKDDFES(0.07)EEEDVKS(0.416)T(0.416)QPIS(0.089)S(0.009)VGKPASVIK 65.059 0.0002454 238530000 2158.2 1726.2 1843.9 2134.4 1768.2 2266.3 1910 1620 2496.4 1648.3 TRUE FALSE FALSE 1987.376193 1875.405036 1912.236556 2125.568418 1747.11537 1796.243834 1963.589459 2113.930542 2222.551166 1705.578302 1.165221315 1.09957135 1.12116609 1.246244992 1.024353656 1.053158234 1.151274882 1.239421573 1.303107083 1 10.73604527 -9.357436851 0.918761989 0.994183652 1.135619746 0 0.11561878 0.566652019 0.798490529 0.056718497 0.012551102 4.39E-10 9.357436851 0.141436093 WDLPDSDWDNDSSSAR ddPTM_HeLa_Curcumin_4h_R1 2 WDLPDSDWDNDSSSAR 16 0 O15020;O15020-2;A4QPE4;E9PJZ2 O15020 SPTBN2 "Spectrin beta chain, non-erythrocytic 2" 0 0 ; ; 188.15 9.51E-06 8845300 2413.92 1895.34 2146.75 1858.86 2413.72 2734.59 1781.66 1906.34 2250.96 1744.58 FALSE FALSE TRUE 2222.855685 2059.164744 2226.310443 1851.16853 2384.937965 2167.405209 1831.648585 2487.57429 2004.03532 1805.204025 1.23135981 1.140682557 1.233273587 1.025462221 1.321145938 1.200642796 1.01464907 1.378001741 1.110143392 1 10.81794619 -9.363488636 0.921554039 0.991729259 1.189161077 0.167229653 0.112872407 0.593506503 0.840177093 0.083226081 0.018308751 4.33E-10 9.363488636 0.197431819 WDQFY(ph)S(ph)EVLGRPT(ph)TLSETMRK ddPTM_HeLa_Curcumin_4h_R1 1 WDQFYSEVLGRPTTLSETMRK 21 2 P36537 P36537 UGT2B10 UDP-glucuronosyltransferase 2B10 3 0 WDQFY(0.978)S(0.993)EVLGRPT(0.341)T(0.341)LS(0.341)ET(0.007)MRK 45.696 0.016069 4023700 1403.3 963.69 1121.1 1316.8 1262.5 1228.8 1008.5 752.29 1435.9 1106.2 TRUE FALSE FALSE 1292.227324 1046.987069 1162.648952 1311.351431 1247.445512 973.9330286 1036.795796 981.6597579 1278.385362 1144.640368 1.128937403 0.914686481 1.015732963 1.145644927 1.089814362 0.850863779 0.905783008 0.857614134 1.116844555 1 10.16067868 -5.259484429 24.98393699 1.055664882 0.874856569 0.621883171 0.06691178 96.0797165 1227870.001 0.010397677 0.0250902 5.50E-06 5.259484429 -0.180808314 WDQTADQT(ph)PGAT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 3 WDQTADQTPGATPK 14 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 2 0 WDQT(0.001)ADQT(0.999)PGAT(1)PK;WDQT(0.004)ADQT(0.996)PGAT(1)PK;WDQT(0.001)ADQT(0.999)PGAT(1)PK ;; 112.3 0.0040937 68639000 12682.2 11479.8 12554.5 13437.1 13358.5 18631.1 14576.8 5846.1 14111.4 13349.4 TRUE FALSE FALSE 11678.39049 12472.06276 13019.78081 13381.50084 13199.20861 14766.79984 14985.78578 7628.548978 12563.41472 13813.29066 0.845445939 0.902903086 0.942554612 0.968740988 0.955544116 1.069028388 1.084881666 0.552261526 0.909516424 1 13.75376942 -5.958272907 0.006551378 1.838930419 2.04E-05 0.023124 0.140139616 33968.86495 73.04963767 10033.69626 10470.57819 1.10E-06 5.958272907 -1.838910016 WDQTADQT(ph)PGATPK ddPTM_HeLa_Curcumin_4h_R1 1 WDQTADQTPGATPK 14 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 WDQTADQT(0.594)PGAT(0.406)PK 142.4 0.0020488 46862000 5814 4610.3 5167 5925.1 5618.2 7129.2 6074.4 2327.1 5445 5241.1 TRUE FALSE FALSE 5353.815765 5008.793789 5358.493565 5900.583506 5551.206634 5650.523557 6244.831316 3036.622077 4847.697123 5423.227835 0.987200967 0.923581664 0.988063517 1.088020582 1.023598271 1.04191152 1.151497135 0.559928915 0.893876723 1 12.40493607 -4.249875516 24.91247287 1.008080183 0.559928637 0.787280209 0.070305482 495.3437696 1067117.916 0.00837259 0.177448964 5.63E-05 4.249875516 -0.448151546 WDQTADQTPGAT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 2 WDQTADQTPGATPK 14 0 O75533 O75533 SF3B1 Splicing factor 3B subunit 1 1 0 WDQTADQT(0.001)PGAT(0.999)PK;WDQTADQT(0.037)PGAT(0.963)PK ; 132.64 0.002915 91734000 8883.3 7479.2 7928.8 8653.3 8331.8 11298.9 9224.9 4462.1 9017.7 7955.4 TRUE FALSE FALSE 8180.177431 8125.668721 8222.648303 8617.494937 8232.448727 8955.380775 9483.725866 5822.573749 8028.480871 8231.849558 0.993722902 0.987101218 0.998882237 1.046847963 1.000072787 1.087894125 1.152077161 0.707322663 0.975294898 1 13.0070009 -4.244522879 24.97141842 1.013773949 0.707322415 0.757612879 0.053766906 1336.112536 1972282.675 0.007469079 0.28725259 5.69E-05 4.244522879 -0.306451534 WDS(ph)YENLSADGEVLHTQGPVDGSLYAK ddPTM_HeLa_Curcumin_4h_R1 1 WDSYENLSADGEVLHTQGPVDGSLYAK 27 0 Q68CZ2;E9PCX8;C9JHU5;Q68CZ2-3 Q68CZ2 TNS3 Tensin-3 1 0 WDS(0.983)Y(0.002)ENLS(0.015)ADGEVLHTQGPVDGSLYAK 60.562 0.0015082 28025000 1270.8 1118.3 1347.7 852.09 1134.6 2235.2 1334.2 600.95 1429.2 876.13 TRUE FALSE FALSE 1170.214839 1214.960869 1397.646948 848.5642774 1121.070636 1771.594324 1371.634061 784.1768886 1272.420336 906.5754523 1.290807992 1.340165196 1.541677468 0.936010649 1.236599373 1.954160925 1.512983898 0.864988001 1.403545984 1 9.824283287 -8.943972592 0.436280561 0.930723043 1.377370652 0 0.318051182 2.286203692 0.694220288 0.454241164 0.099040198 1.14E-09 8.943972592 0.446647609 WDSYENLS(ph)ADGEVLHTQGPVDGSLYAK ddPTM_HeLa_Curcumin_4h_R1 2 WDSYENLSADGEVLHTQGPVDGSLYAK 27 0 Q68CZ2;E9PCX8;C9JHU5;Q68CZ2-3 Q68CZ2 TNS3 Tensin-3 1 0 WDS(0.007)YENLS(0.982)ADGEVLHT(0.011)QGPVDGSLYAK;WDS(0.265)Y(0.005)ENLS(0.723)ADGEVLHT(0.008)QGPVDGSLYAK ; 148.6 7.08E-09 185013000 4683.7 3712.4 4644.6 3841.6 5338.4 9209.2 5697.8 2476.24 4348.5 3660.6 TRUE FALSE FALSE 4312.980203 4033.283314 4816.732962 3825.704477 5274.743067 7299.108111 5857.664933 3231.234177 3871.480429 3787.805578 1.138648781 1.064807375 1.27164208 1.010005503 1.392559084 1.927001785 1.546453431 0.85306231 1.022090588 1 11.88714657 -5.669571843 5.326159777 1.080954769 1.483252445 0.299757678 0.25598703 0.174333209 7.965673083 0.036223069 0.073167394 2.14E-06 5.669571843 0.402297676 WDVDDWDNENSSAR ddPTM_HeLa_Curcumin_4h_R1 2 WDVDDWDNENSSAR 14 0 A0A087WUZ3;Q01082;Q01082-2;F8W6C1 A0A087WUZ3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 ; ; 309.35 1.40E-91 92236000 4548.7 4452.7 4412 5146.7 5363.7 5106.2 4804.6 4681.9 4388.8 4017.5 FALSE FALSE TRUE 4188.665595 4837.571547 4575.512601 5125.404319 5299.741381 4047.116561 4939.404145 6109.389757 3907.35962 4157.107826 1.00759128 1.163686811 1.100648045 1.232925518 1.274862621 0.973541397 1.188182831 1.469625041 0.939922606 1 12.02136445 -1 0.199270918 0.969324172 2.720907444 0.515826608 0.108811262 32.72535145 0.37474313 0.105858204 18.0159669 0.1 1 1.751583272 WEADTLDKEGLSES(ph)VR ddPTM_HeLa_Curcumin_4h_R1 1 WEADTLDKEGLSESVR 16 1 Q6PHR2-3;Q6PHR2;Q6PHR2-4 Q6PHR2-3 ULK3 Serine/threonine-protein kinase ULK3 1 0 WEADTLDKEGLS(0.04)ES(0.96)VR 61.561 0.016912 11270000 2495.3 2027 2219.7 2536.5 2468.7 3263.6 2302.6 1878.9 2915.7 2959.7 TRUE FALSE FALSE 2297.794372 2202.204848 2301.964035 2526.004635 2439.262365 2586.692572 2367.204759 2451.767961 2595.855005 3062.549355 0.750288112 0.719075709 0.751649612 0.824804548 0.796480997 0.844620697 0.772952362 0.800564392 0.847612464 1 11.58051738 -9.243692345 0.934592484 1.002429523 0.782137264 0.40776585 0.057490253 0.191536037 0.295386192 0.028769109 0.007592929 5.71E-10 9.243692345 -0.220292259 WEAERDDWLHNR ddPTM_HeLa_Curcumin_4h_R1 1 WEAERDDWLHNR 12 1 Q03701 Q03701 CEBPZ CCAAT/enhancer-binding protein zeta 0 0 115 0.0018896 5558400 3429.1 2730.4 2855.1 2846.9 2568.1 3222.9 3251.1 1889.1 3368.2 3091.6 FALSE FALSE TRUE 3157.683117 2966.40361 2960.912518 2835.120282 2537.477085 2554.43421 3342.317116 2465.077894 2998.716887 3199.03287 0.987074296 0.927281379 0.925564894 0.886242936 0.793201317 0.798502021 1.044789864 0.77056973 0.93738233 1 11.6434201 -6.812189036 1.213848034 0.995571727 0.86225445 0.301382844 0.074521459 0.313821969 0.923144603 0.012791081 0.018795644 1.54E-07 6.812189036 -0.133317277 WEDRWEWLR ddPTM_HeLa_Curcumin_4h_R1 1 WEDRWEWLR 9 1 A0A087WUZ3;Q01082;Q01082-2;Q01082-3 A0A087WUZ3;Q01082-3 SPTBN1 "Spectrin beta chain, non-erythrocytic 1" 0 0 94.309 0.0142 9709200 2413 1866.1 2391.8 1951.7 2197.8 3711.9 3266.2 2283.8 2704.8 2434.5 FALSE FALSE TRUE 2222.008504 2027.397369 2480.442212 1943.624383 2171.59267 2942.010098 3357.840781 2980.120107 2408.090207 2519.098694 0.882064887 0.804810615 0.984654638 0.771555472 0.862051446 1.167882031 1.332953246 1.183010461 0.955933252 1 11.29869193 -5.131865907 4.231173025 0.917758964 1.256375591 0.785943165 0.079818821 0.086121438 2.543925348 0.012449291 0.033792921 7.38E-06 5.131865907 0.338616627 WEETRTPESQPDT(ph)PPGTPLVSQDEKR ddPTM_HeLa_Curcumin_4h_R1 2 WEETRTPESQPDTPPGTPLVSQDEKR 26 2 A0A0D9SEV0;M0R000;M0QYI1;A0A0D9SFD6;M0R3C8;A0A0D9SFL2;M0QYH2;Q96T60-2;Q96T60 A0A0D9SEV0 PNKP Bifunctional polynucleotide phosphatase/kinase;Polynucleotide 3-phosphatase;Polynucleotide 5-hydroxyl-kinase 1 0 WEET(0.002)RT(0.01)PES(0.101)QPDT(0.885)PPGT(0.001)PLVSQDEKR;WEET(0.001)RT(0.001)PES(0.053)QPDT(0.944)PPGTPLVSQDEKR ; 91.883 5.05E-06 48343000 2699.2 1953.97 1824.46 2011.74 2182.46 3566.2 2413.9 2258.97 3154.7 2643.3 TRUE FALSE FALSE 2485.555472 2122.86246 1892.076093 2003.415953 2156.43559 2826.529921 2481.627537 2947.719554 2808.637303 2735.154478 0.908744092 0.776139877 0.691762059 0.732469032 0.788414551 1.033407781 0.907307999 1.077715931 1.02686606 1 11.4174066 -3.796358466 1.29892404 0.89935068 1.395094665 0.184616203 0.119283359 6.733685735 4.256029061 0.020083003 5.952540623 0.000159824 3.796358466 0.495743985 WGDAGAEYVVESTGVFTTMEK ddPTM_HeLa_Curcumin_4h_R1 1 WGDAGAEYVVESTGVFTTMEK 21 0 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 0 102.39 9.15E-05 313000 191.72 115.78 163.85 307.52 176.47 0 106.4 0 0 63.424 FALSE FALSE TRUE 176.5451597 125.7875073 169.9224251 306.2475637 174.3657105 0 109.3852976 0 0 65.62797928 2.690089831 1.916675002 2.589176552 4.666417694 2.656880684 0 1.666747915 0 0 1 6.036239107 -5.265314062 24.98297663 2.155410314 0.666699154 0.277092784 1.223008633 356.9681001 2301648.584 0.171284193 0.396921057 5.43E-06 5.265314062 -1.488711159 WGDYDSHDIER ddPTM_HeLa_Curcumin_4h_R1 4 WGDYDSHDIER 11 0 Q6P2Q9 Q6P2Q9 PRPF8 Pre-mRNA-processing-splicing factor 8 0 0 ;;; ;;; 199.19 5.00E-06 121704200 32061.3 29412 29775.9 33990.1 29722.7 31937.2 28654 23435.9 33372.5 29721.4 FALSE FALSE TRUE 29523.61427 31954.24222 30879.42105 33849.45797 29368.27622 25313.06471 29457.95412 30581.39802 29711.62024 30754.21644 0.959985904 1.039019878 1.004071136 1.100644461 0.954934953 0.823076236 0.957850907 0.99438066 0.966099081 1 14.9084966 -5.526695403 24.99982501 0.996192462 0.921815451 0.311905691 0.055992143 112.2416372 735202.2161 0.008265409 0.016588292 2.97E-06 5.526695403 -0.074377011 WGQPPSPT(ph)PVPRPPDADPNTPSPKPLEGRPER ddPTM_HeLa_Curcumin_4h_R1 1 WGQPPSPTPVPRPPDADPNTPSPKPLEGRPER 32 3 F5GWX5;A0A2R8YER1;Q14839-2;Q14839;A0A2R8YFD8;A0A0C4DGG9;A0A2U3TZM0;A0A2R8Y521;A0A2R8YFK9;A0A2R8Y5J0;A0A2R8Y425;A0A2R8Y445;A0A2R8Y212;A0A2R8Y8C1;A0A2R8YDJ9;A0A2R8YD40;A0A2R8Y5Z7;A0A2R8Y685;A0A2R8Y8B3 F5GWX5 CHD4 Chromodomain-helicase-DNA-binding protein 4 1 0 WGQPPS(0.175)PT(0.55)PVPRPPDADPNT(0.073)PS(0.202)PKPLEGRPER 48.321 0.0046108 73292000 2274.2 1758.5 1805.7 1894.5 1764.1 2309.8 1641.4 1410.5 2357.7 2046.9 TRUE FALSE FALSE 2094.19467 1910.496904 1872.62083 1886.661061 1743.06426 1830.721443 1687.453266 1840.554957 2099.066209 2118.029623 0.988746639 0.90201614 0.884133447 0.890762358 0.822965005 0.864351199 0.796709002 0.868993964 0.991046672 1 11.04850705 -6.903333407 0.956116698 0.999186351 0.839318977 0.865656911 0.024678222 0.104031988 0.188672252 0.004684997 0.006773961 1.25E-07 6.903333407 -0.159867374 WGRDDIENIAR ddPTM_HeLa_Curcumin_4h_R1 2 WGRDDIENIAR 11 1 O60264 O60264 SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 0 0 ; ; 150.09 0.00054147 19868100 5794.2 4150.6 5181.9 5490.3 4926.2 6709.6 5049.6 4406 5848.8 5108.5 FALSE FALSE TRUE 5335.582956 4509.359369 5373.945772 5467.582593 4867.458282 5317.953327 5191.278186 5749.369117 5207.201273 5286.019995 1.009376234 0.853072704 1.016633645 1.034347694 0.920817229 1.006041092 0.982076911 1.087655575 0.985089212 1 12.36796617 -2.945704789 14.14439796 0.995057751 0.996565159 0 0.06072309 0 0 0.007455389 0 0.00113317 2.945704789 0.001507409 WGTDEDKFTEILCLR ddPTM_HeLa_Curcumin_4h_R1 2 WGTDEDKFTEILCLR 15 1 P12429;D6RA82;D6RFJ9 P12429 ANXA3 Annexin A3;Annexin 0 0 ; ; 153.49 0.00034778 59253000 3933 3551.8 3910.3 3211.6 3061.4 7196.9 5038.9 4305.9 4897.7 4305.8 FALSE FALSE TRUE 3621.6989 3858.801765 4055.219158 3198.31125 3024.894804 5704.181814 5180.277972 5618.749088 4360.434563 4455.42623 0.812873721 0.866090373 0.910175357 0.717846304 0.678923777 1.280277469 1.162689652 1.261102485 0.978679556 1 12.12134774 -5.245882737 24.84162389 0.877787431 1.227489883 0.744684014 0.101861716 352.4532067 562813.7117 0.016470691 0.041824346 5.68E-06 5.245882737 0.349702453 WGTDEEKFITIFGTR ddPTM_HeLa_Curcumin_4h_R1 2 WGTDEEKFITIFGTR 15 1 P08758;D6RBE9;D6RBL5 P08758 ANXA5 Annexin A5;Annexin 0 0 ; ; 127.78 0.00065885 67172000 5041.6 3581.9 4137.5 3941.6 3684.1 6047.7 4801.7 5189.8 5000.8 4264.1 FALSE FALSE TRUE 4642.55204 3891.503475 4290.83939 3925.290704 3640.169514 4793.338848 4936.422779 6772.146129 4452.224751 4412.277158 1.052189578 0.881971675 0.972477303 0.889629224 0.82500926 1.086363952 1.118792542 1.534841509 1.009053736 1 12.1073077 -4.159205759 1.716969482 0.989529246 1.824452521 0.829870175 0.077628277 0.42574929 0.9932557 0.012443785 0.628557032 6.93E-05 4.159205759 0.834923275 WIDLTMEDIRR ddPTM_HeLa_Curcumin_4h_R1 1 WIDLTMEDIRR 11 1 A0A0A0MSW4;P48739;P48739-2;P48739-3 A0A0A0MSW4 PITPNB Phosphatidylinositol transfer protein beta isoform 0 0 141.89 0.00016116 0 2658.9 2182.3 2150.1 2301.3 2152.1 3689.7 2415 2391 2846 2509.1 FALSE FALSE TRUE 2448.445259 2370.928288 2229.784597 2291.77783 2126.437613 2924.414629 2482.7584 3120.004893 2533.80092 2596.291038 0.943055005 0.913198194 0.858834609 0.882712222 0.819028985 1.126381667 0.956271221 1.201716159 0.975931004 1 11.3422364 -2.229090776 1.034197538 0.948579036 18.0930946 0.490821479 0.080078859 81.76263539 1.596222548 0.01247671 3185.685057 0.005900777 2.229090776 17.14451556 WIDNPTVDDR ddPTM_HeLa_Curcumin_4h_R1 3 WIDNPTVDDR 10 0 P18206;P18206-2 P18206 VCL Vinculin 0 0 ;; ;; 187.97 0.0012671 30231000 6510.2 5070 6763 5863.6 7688.3 7012 6227.7 6070.2 5373.3 4735.4 FALSE FALSE TRUE 5994.9108 5508.228209 7013.642729 5839.337977 7596.622044 5557.632158 6402.432501 7920.976036 4783.862433 4899.954798 1.22346247 1.124138576 1.431368863 1.191712621 1.550345331 1.134221108 1.306630931 1.616540634 0.976307462 1 12.25855272 -8.839293585 0.051073282 4.19E-10 2.238781692 0.54174094 0.14055715 57.26849671 0.944375773 24.20351622 17.21661639 1.45E-09 8.839293585 2.238781692 WIFVGGK ddPTM_HeLa_Curcumin_4h_R1 2 WIFVGGK 7 0 O43681 O43681 ASNA1 ATPase ASNA1 0 0 ; ; 128 0.0087145 1071230 2500.89 1893.71 1842.95 2068.94 2202.02 2362.77 1967.16 1719.96 2172.86 1955.46 FALSE FALSE TRUE 2302.941918 2057.393854 1911.251348 2060.379274 2175.76235 1872.704868 2022.353215 2244.367886 1934.502694 2023.412089 1.13814775 1.016794288 0.944568513 1.018269726 1.075293738 0.925518276 0.999476689 1.109199603 0.95605967 1 10.98257445 -7.030711058 24.64731461 1.065880366 1.008204194 0 0.068839239 881.6875355 707601.0807 0.011618815 0.01423932 9.32E-08 7.030711058 -0.057676172 WIGLDLSNGKPR ddPTM_HeLa_Curcumin_4h_R1 1 WIGLDLSNGKPR 12 1 P17987;E7EQR6;F5H282 P17987 TCP1 T-complex protein 1 subunit alpha 0 0 116.74 0.00063369 4005200 4221.5 2696 2974.6 2881.1 2990.1 5654.3 4079.5 3918.7 3788 3302.7 FALSE FALSE TRUE 3887.36382 2929.030227 3084.841293 2869.178772 2954.44501 4481.534443 4193.959791 5113.493591 3372.465877 3417.468579 1.137498043 0.857075979 0.902668517 0.83956259 0.864512706 1.311360833 1.227212392 1.496281084 0.986831568 1 11.73871236 -5.185777581 7.195589829 1.009093744 1.336385956 0.690293016 0.117940029 0.163866063 13.56947295 0.01958662 0.050316904 6.52E-06 5.185777581 0.327292212 WIPGAADDSKLEVFTT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 WIPGAADDSKLEVFTTPK 18 1 Q8WYP5;Q8WYP5-3;Q8WYP5-2 Q8WYP5 AHCTF1 Protein ELYS 1 0 WIPGAADDSKLEVFT(0.266)T(0.734)PK 75.017 0.0081351 36409000 2776.2 2025.9 2727.4 3108.9 2731.5 4009 2743.8 962.46 3638.7 2731.1 TRUE FALSE FALSE 2556.460841 2201.009769 2828.479843 3096.036196 2698.928647 3177.488209 2820.783643 1255.909623 3239.543714 2826.005522 0.904619903 0.778841284 1.000875554 1.095552069 0.955033041 1.124374381 0.998152205 0.444411596 1.146333115 1 11.46454857 -4.259451203 24.94587507 0.968272007 0.444411412 0.699832772 0.107399849 68.57108781 860301.8431 0.01331568 0.11627101 5.50E-05 4.259451203 -0.523860595 WISENQDSADVDPQEHS(ph)FTR ddPTM_HeLa_Curcumin_4h_R1 2 WISENQDSADVDPQEHSFTR 20 0 Q15751 Q15751 HERC1 Probable E3 ubiquitin-protein ligase HERC1 1 0 WISENQDSADVDPQEHS(0.952)FT(0.048)R;WISENQDSADVDPQEHS(0.913)FT(0.087)R ; 149.93 1.74E-05 24585000 3065.2 3010.4 2966.4 3702.4 3418.5 3655.9 2611.5 2237.84 3506.2 3492.7 TRUE FALSE FALSE 2822.586186 3270.605562 3076.337394 3687.08045 3377.73662 2897.62513 2684.771662 2920.147114 3121.578632 3614.071065 0.780999082 0.904964375 0.851211096 1.020201425 0.93460714 0.801762079 0.742866317 0.807993828 0.863729179 1 11.81940916 -9.516576553 1.24981882 1.000575426 0.85059469 0.021233926 0.087278396 0.473452688 1.315765322 0.060875242 0.014412862 3.04E-10 9.516576553 -0.149980736 WISIMTER ddPTM_HeLa_Curcumin_4h_R1 4 WISIMTER 8 0 P07355;H0YN42;H0YMU9;H0YMD0;A6NMY6;H0YM50;H0YNP5;H0YN28;H0YL33;P07355-2 P07355;P07355-2 ANXA2;ANXA2P2 Annexin A2;Annexin;Putative annexin A2-like protein 0 0 ;;; ;;; 191.63 1.27E-14 130763100 8578.84 5124.29 6614.65 7488.4 7207.45 11066.58 9542.52 9621.69 8355.58 6902.19 FALSE FALSE TRUE 7899.815762 5567.210794 6859.794748 7457.414985 7121.505866 8771.246562 9810.257429 12555.29899 7438.993779 7142.040589 1.106100653 0.779498622 0.960481065 1.044157463 0.99712481 1.228114914 1.373593066 1.757942822 1.0415782 1 12.80212062 -4.338513021 1.139383335 1.018549855 2.042208353 0.881408126 0.08881623 0.38720087 0.443693635 0.014738044 0.455719911 4.59E-05 4.338513021 1.023658498 WKDSDEADLVLAK ddPTM_HeLa_Curcumin_4h_R1 2 WKDSDEADLVLAK 13 1 Q13185 Q13185 CBX3 Chromobox protein homolog 3 0 0 ; ; 164.2 0.00015009 85152000 6538.8 5675.9 6499.4 6771 6129.8 7680.4 5928.4 5575.6 6811 6490.1 FALSE FALSE TRUE 6021.24708 6166.499505 6740.273481 6742.983396 6056.706139 6087.398464 6094.734949 7275.574773 6063.85034 6715.630492 0.896601903 0.918230911 1.003669498 1.004073021 0.901881982 0.906452264 0.907544713 1.083379257 0.902945799 1 12.71330714 -4.250924661 24.29963654 0.946644985 1.083379372 0.481509163 0.044458785 814.4002492 1882033.433 0.007094736 0.129611445 5.61E-05 4.250924661 0.136734387 WKDTDEADLVLAK ddPTM_HeLa_Curcumin_4h_R1 2 WKDTDEADLVLAK 13 1 P45973 P45973 CBX5 Chromobox protein homolog 5 0 0 ; ; 159.52 0.00024501 25920000 8668.3 6409.5 7254.3 8082.2 7947.5 9400.8 7930.9 6710.1 8739.8 8040.7 FALSE FALSE TRUE 7982.194908 6963.50862 7523.15074 8048.757998 7852.731253 7450.968111 8153.419709 8755.9786 7781.065806 8320.113727 0.959385313 0.83694873 0.904212489 0.967385575 0.94382499 0.895536811 0.979964935 1.052386889 0.935211472 1 13.02238753 -8.169266561 1.524905586 0.990237383 0.939154521 0 0.056934579 0.516865332 2.436097808 0.013591982 0.010931209 6.77E-09 8.169266561 -0.051082862 WKEPGSGGPQNLS(ph)GPGGR ddPTM_HeLa_Curcumin_4h_R1 2 WKEPGSGGPQNLSGPGGR 18 1 M0QZH1;M0QX70;M0QYR7;M0R2N0;M0QZC7;Q9H0W8-2;Q9H0W8 M0QZH1 SMG9 Protein SMG9 1 0 WKEPGSGGPQNLS(1)GPGGR;WKEPGSGGPQNLS(1)GPGGR ; 113.59 0.00024517 206868000 4452.6 3908.5 3588.1 4007.9 3585.8 4421.1 2870.4 2037.48 4174.3 3759.1 TRUE FALSE FALSE 4100.172012 4246.333324 3721.078142 3991.316372 3543.041677 3504.114024 2950.935699 2658.698273 3716.389734 3889.728445 1.05410238 1.091678605 0.95664214 1.026116971 0.910871216 0.900863408 0.758648255 0.683517708 0.955436809 1 11.92545372 -4.687244649 0.796939856 1.029168136 0.58298451 0.871675902 0.043612593 0.307915944 0.202607309 0.006302588 0.106214674 2.05E-05 4.687244649 -0.446183626 WLAES(ph)PVGLPPEEEDK ddPTM_HeLa_Curcumin_4h_R1 1 WLAESPVGLPPEEEDK 16 0 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 WLAES(1)PVGLPPEEEDK 69.261 0.012355 36770000 1862.1 1382.3 1747.5 1358 1521.2 2504.2 1891.9 1668.6 1986.5 1618.1 TRUE FALSE FALSE 1714.71282 1501.779853 1812.263887 1352.380956 1503.060684 1984.800692 1944.981622 2177.348459 1768.58592 1674.328855 1.024119494 0.896944378 1.082382283 0.807715254 0.897709359 1.18543062 1.161648512 1.300430589 1.056295432 1 10.7093672 -5.153718578 5.573423068 0.986271277 1.216685575 0.634914305 0.085948109 0.118484132 5.162521506 0.011882468 0.031017636 7.02E-06 5.153718578 0.230414298 WLAES(ph)PVGLPPEEEDKLTR ddPTM_HeLa_Curcumin_4h_R1 4 WLAESPVGLPPEEEDKLTR 19 1 E9PGC8;P78559;P78559-2 E9PGC8 MAP1A Microtubule-associated protein 1A;MAP1A heavy chain;MAP1 light chain LC2 1 0 WLAES(1)PVGLPPEEEDKLTR;WLAES(1)PVGLPPEEEDKLTR;WLAES(1)PVGLPPEEEDKLTR;WLAES(1)PVGLPPEEEDKLTR ;;; 118.46 0.00011251 53216000 12583.2 9121.3 9972.7 9815.6 7848.2 7838.4 5085.6 5147.6 12295.9 11238.4 TRUE FALSE FALSE 11587.22644 9909.704528 10342.29703 9774.985648 7754.615341 6212.627483 5228.288249 6717.079543 10947.07053 11628.93356 0.996413504 0.852159355 0.889359027 0.840574554 0.666838047 0.534238797 0.449593096 0.577617845 0.941364956 1 13.50543118 -5.802103037 0.804226227 0.996257956 0.469767888 0.920627519 0.053837341 0.110092784 0.13077067 0.009152874 0.032401192 1.58E-06 5.802103037 -0.526490069 WLDDLLAS(ph)PPPS(ph)GGGAR ddPTM_HeLa_Curcumin_4h_R1 1 WLDDLLASPPPSGGGAR 17 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 2 0 WLDDLLAS(1)PPPS(1)GGGAR 88.319 0.012262 3981500 2157.6 1669.6 1564.6 2022.5 1892.3 3557.9 3338.5 1992.9 1816.8 1499.9 TRUE FALSE FALSE 1986.823683 1813.912784 1622.585452 2014.131431 1869.735558 2819.951434 3432.169325 2600.526036 1617.501585 1552.021413 1.280152236 1.168742112 1.045465893 1.297747192 1.204709898 1.816953948 2.211418796 1.675573554 1.04219025 1 10.59993275 -5.233951324 3.389355136 1.144574635 1.96017722 0.839422367 0.151626555 0.067876509 1.625049484 0.022475386 0.060147212 5.84E-06 5.233951324 0.815602585 WLDDLLAS(ph)PPPSGGGAR ddPTM_HeLa_Curcumin_4h_R1 3 WLDDLLASPPPSGGGAR 17 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 WLDDLLAS(0.994)PPPS(0.006)GGGAR;WLDDLLAS(0.98)PPPS(0.02)GGGAR;WLDDLLAS(0.999)PPPS(0.001)GGGAR ;; 152.94 0.00019319 295574000 14435.3 12355.4 13007.9 13498.9 11640.6 15466.7 10272.6 12945 16393.1 14782.5 TRUE FALSE FALSE 13292.73077 13423.34572 13489.98422 13443.04513 11501.79345 12258.73207 10560.82151 16891.87091 14594.81794 15296.19077 0.869022292 0.877561343 0.881917885 0.878849207 0.751938415 0.801423848 0.690421665 1.104318791 0.954147223 1 13.9008848 -8.958073478 0.419012344 1.03182388 0.83446041 0.169541668 0.10344417 1.859132322 0.514135248 0.159733162 0.034033845 1.10E-09 8.958073478 -0.19736347 WLDES(ph)DAEMELR ddPTM_HeLa_Curcumin_4h_R1 7 WLDESDAEMELR 12 0 H3BPZ1;H3BS72;Q9P035 H3BPZ1 HACD3 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 1 0 WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR;WLDES(1)DAEMELR ;;;;;; 245.55 1.12E-26 58837000 14683.2 12385.8 16325.6 20351.6 18479.2 32130 12337.2 6520.99 19727.5 16431.3 TRUE FALSE FALSE 13521.00923 13456.37336 16930.6411 20267.39047 18258.84761 25465.87582 12683.34863 8509.209832 17563.44261 17002.28645 0.795246525 0.791444927 0.995786134 1.192039114 1.073905422 1.497791247 0.745978999 0.500474442 1.033004746 1 14.05344115 -6.549437419 19.70418766 0.892285357 1.026803338 0.027306623 0.256559001 52.06608189 38627.13813 0.041422059 0.058585055 2.82E-07 6.549437419 0.134517981 WLDGAS(ph)FDNER ddPTM_HeLa_Curcumin_4h_R1 1 WLDGASFDNER 11 0 E7EMW7;O95071-2;O95071 E7EMW7 UBR5 E3 ubiquitin-protein ligase UBR5 1 0 WLDGAS(1)FDNER 115.34 0.0048057 3892200 1139.6 827.48 842.3 854.67 1234.3 2564.8 2485.6 1083 1067.4 1055.8 TRUE FALSE FALSE 1049.399457 899.003684 873.516379 851.133602 1219.581779 2032.831569 2555.339246 1413.201714 950.3088905 1092.488971 0.960558399 0.822894974 0.799565398 0.779077523 1.116333263 1.860734179 2.339006904 1.293561538 0.869856736 1 10.093403 -5.312519215 3.960778492 0.941016784 1.889982455 0.740640414 0.251212303 0.076428112 2.506541291 0.033035308 0.079986784 4.87E-06 5.312519215 0.948965671 WLEASEEER ddPTM_HeLa_Curcumin_4h_R1 2 WLEASEEER 9 0 Q14137;Q14137-2 Q14137 BOP1 Ribosome biogenesis protein BOP1 0 0 ; ; 180.45 0.0059982 31718000 3097.5 2600.5 2894.4 2873.3 2641.6 3649.7 2588 2276.72 3224.5 2909.3 FALSE FALSE TRUE 2852.329607 2825.275632 3001.66901 2861.411046 2610.100645 2892.711079 2660.612315 2970.881447 2870.780417 3010.397958 0.947492539 0.938505696 0.997100401 0.95050923 0.86702844 0.960906538 0.883807507 0.986873326 0.953621567 1 11.5557385 -10.01122382 0.22391864 1.057617021 0.923934456 0.071856846 0.040410677 9.426529304 0.491887151 0.35552133 0.039415313 9.74E-11 10.01122382 -0.133682566 WLEEADSSSGS(ph)PTSIDK ddPTM_HeLa_Curcumin_4h_R1 1 WLEEADSSSGSPTSIDK 17 0 P20265-3;P20265-2;P20265 P20265-3 POU3F2 "POU domain, class 3, transcription factor 2" 1 0 WLEEADS(0.081)S(0.081)S(0.081)GS(0.747)PT(0.009)S(0.002)IDK 92.952 0.0035121 2163000 1059.3 855.83 704.85 884.3 1152.5 912.89 812.42 353.11 757.95 893.63 TRUE FALSE FALSE 975.4552872 929.8041317 730.972361 880.6410009 1138.75719 723.5463236 835.2143187 460.7716135 674.8047813 924.683576 1.054907119 1.00553763 0.790510808 0.952370112 1.231510129 0.782479912 0.90324338 0.498301933 0.729768322 1 9.852815954 -3.978184403 1.160662375 1.009890094 2.78E-16 0.404454651 0.149175217 1.363586818 0.972992091 0.017198992 1.946463226 0.000105152 3.978184403 -1.009890094 WLKEDKLECSEELGDLVK ddPTM_HeLa_Curcumin_4h_R1 1 WLKEDKLECSEELGDLVK 18 2 A0A087WVQ6;Q00610-2;Q00610;A0A087WX41;P53675-2;P53675 A0A087WVQ6 CLTC;CLTCL1 Clathrin heavy chain;Clathrin heavy chain 1;Clathrin heavy chain 2 0 0 62.813 0.0091321 18882000 2893.9 2519.5 2723.1 2886.7 2595.1 3170.7 2701.3 2464.8 3148.4 2777.8 FALSE FALSE TRUE 2664.844761 2737.274353 2824.020481 2874.7556 2564.155127 2513.061079 2777.091208 3216.306173 2803.028397 2874.328343 0.927119119 0.952317908 0.982497524 1.000148646 0.892088454 0.874312458 0.966170484 1.118976606 0.975194224 1 11.48900916 -9.616087516 1.442850973 0.999865687 0.955504399 0.001446328 0.064425103 1.060466542 3.983248506 0.044750135 0.010405879 2.42E-10 9.616087516 -0.044361287 WLNSGRGDEASEEGQNGS(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 2 WLNSGRGDEASEEGQNGSSPK 21 1 E7EV99;E7ENY0;P35611-5;P35611-2;P35611-6;P35611-4;P35611;P35611-3;H0Y9H2 E7EV99 ADD1 Alpha-adducin 1 0 WLNSGRGDEAS(0.001)EEGQNGS(0.741)S(0.258)PK;WLNSGRGDEASEEGQNGS(0.57)S(0.43)PK ; 66.264 0.0017778 142008000 4379.3 3138.4 3642.5 4027.2 3230.2 4497.7 3181.8 2503.36 5375.3 4034 TRUE FALSE FALSE 4032.673784 3409.669312 3777.494254 4010.536513 3191.681975 3564.82632 3271.072745 3266.62294 4785.643038 4174.1812 0.96609936 0.81684746 0.904966525 0.960795979 0.764624683 0.854018106 0.783644166 0.782578135 1.146486654 1 12.02727751 -6.019698681 0.305637118 1.013690911 0.723041721 0.639587343 0.069361817 1.131156377 0.185886862 0.032600469 0.11785946 9.56E-07 6.019698681 -0.29064919 WLNSGRGDEASEEGQNGSS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 WLNSGRGDEASEEGQNGSSPK 21 1 E7EV99;E7ENY0;P35611-5;P35611-2;P35611-6;P35611-4;P35611;P35611-3;H0Y9H2 E7EV99 ADD1 Alpha-adducin 1 0 WLNSGRGDEASEEGQNGS(0.096)S(0.904)PK 102.84 3.52E-05 12604000 876.03 714.9 945.25 860.71 700.11 1003.1 787.62 488.88 943.5 1002.7 TRUE FALSE FALSE 806.6913011 776.6927705 980.2817965 857.1486101 691.7616455 795.0457527 809.7184974 637.9372615 840.0004105 1037.54375 0.777500998 0.748587971 0.944810083 0.826132498 0.666730097 0.766276846 0.780418654 0.61485336 0.80960481 1 10.01895646 -13.52287875 0.138909764 1.837790498 0.668988526 0.237321223 0.094879032 38.97972038 0.377500689 8.992061868 0.232512042 3.00E-14 13.52287875 -1.168801972 WLPSS(ph)PSGVAK ddPTM_HeLa_Curcumin_4h_R1 1 WLPSSPSGVAK 11 0 Q8IWI9-3;Q8IWI9;H3BP52;H3BTF4 Q8IWI9-3 MGA MAX gene-associated protein 1 0 WLPS(0.17)S(0.817)PS(0.013)GVAK 103.43 0.0091367 47535000 2004.6 1213.4 1910.8 2328 1947 2140.8 2069.3 1134.6 2699.1 1718 TRUE FALSE FALSE 1845.933795 1318.280889 1981.615929 2318.367353 1923.783297 1696.773948 2127.358989 1480.534317 2403.015483 1777.700372 1.038382971 0.741565288 1.114707495 1.304138419 1.082175223 0.954476904 1.196691536 0.832836816 1.351755065 1 10.79579647 WLREAEEES(ph)DHN ddPTM_HeLa_Curcumin_4h_R1 3 WLREAEEESDHN 12 1 Q04637-9;Q04637;E7EX73;E9PGM1;Q04637-3;Q04637-8;E7EUU4;Q04637-7;Q04637-4;Q04637-5;Q04637-6 Q04637-9 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 1 0 WLREAEEES(1)DHN;WLREAEEES(1)DHN;WLREAEEES(1)DHN ;; 79.886 0.010834 246313000 19290.8 12380.1 9706.4 16066.9 6529.7 16325.4 10247.4 11606 32652.1 22145.7 TRUE FALSE FALSE 17763.91282 13450.18068 10066.12772 16000.41942 6451.837592 12939.32801 10534.91446 15144.61597 29070.24632 22915.26143 0.775200095 0.586952967 0.439276146 0.698242936 0.281551996 0.564659847 0.459733549 0.660896496 1.268597629 1 14.48402112 -7.646519229 0.761246828 0.959921744 0.499695321 0.688601913 0.152350936 0.199738392 0.249872196 0.0323879 0.030002153 2.26E-08 7.646519229 -0.460226423 WLSALEGT(ph)RWLDY(ph)VR ddPTM_HeLa_Curcumin_4h_R1 1 WLSALEGTRWLDYVR 15 1 A4FU01-6;A4FU01-4;A4FU01 A4FU01-6 MTMR11 Myotubularin-related protein 11 2 0 WLS(0.001)ALEGT(0.999)RWLDY(1)VR 115.24 0.0024098 39200000 3157.9 2822.4 2784.3 3126.9 3506.3 5893.4 3965 2204.5 3496.1 2809.7 TRUE FALSE FALSE 2907.948883 3066.35568 2887.488607 3113.961716 3464.489663 4671.042408 4076.247229 2876.641902 3112.586577 2907.336866 1.000210508 1.054695696 0.993173045 1.071070144 1.191636822 1.606639555 1.402055357 0.98944224 1.070597155 1 11.50548253 -5.658460908 3.151295822 1.007067673 1.345917942 0.456450437 0.145458939 0.140141741 2.770659845 0.020251252 0.042922934 2.20E-06 5.658460908 0.338850269 WLYDETLEDR ddPTM_HeLa_Curcumin_4h_R1 1 WLYDETLEDR 10 0 Q9H5Q4 Q9H5Q4 TFB2M "Dimethyladenosine transferase 2, mitochondrial" 0 0 177.3 0.003086 3163300 1344 1019.3 1369.5 1253.4 1314.6 1766.1 1180.5 900.91 1317.2 896.55 FALSE FALSE TRUE 1237.620982 1107.40375 1420.254875 1248.213763 1298.924254 1399.790952 1213.621653 1175.593312 1172.706455 927.7050458 1.334067317 1.193702411 1.530933653 1.345485581 1.400147881 1.508875001 1.308197749 1.267205905 1.264094079 1 9.857522378 -9.074317871 0.481819567 0.932994177 1.385885594 0.27108493 0.124197837 0.6421866 0.224604223 0.138000054 0.026649398 8.43E-10 9.074317871 0.452891417 WMDEAQSLDTADR ddPTM_HeLa_Curcumin_4h_R1 3 WMDEAQSLDTADR 13 0 Q6N069-3;Q6N069-2;Q6N069 Q6N069-3 NAA16 "N-alpha-acetyltransferase 16, NatA auxiliary subunit" 0 0 ;; ;; 214.04 1.75E-12 22260300 5129.1 4534.3 4576.6 4538.6 4491.4 5339 4443.4 3819.99 5144.1 4129.8 FALSE FALSE TRUE 4723.126323 4926.224688 4746.212822 4519.820476 4437.842988 4231.631217 4568.069845 4984.687366 4579.8051 4273.310243 1.105261742 1.152788917 1.110664228 1.057686014 1.038502411 0.990246665 1.068976879 1.166469805 1.071723053 1 12.06113835 -9.324459405 1.104143898 1.00104513 1.084147208 0.065626595 0.053886793 0.547901839 1.218092193 0.034021981 0.009461603 4.74E-10 9.324459405 0.083102078 WMEEQAQSLIDK ddPTM_HeLa_Curcumin_4h_R1 1 WMEEQAQSLIDK 12 0 A0A0A0MRR7;P09234 A0A0A0MRR7 SNRPC U1 small nuclear ribonucleoprotein C 0 0 117.09 0.020213 20942000 968.41 912.51 933.44 883.55 819.91 1129.7 1004.1 796.91 1063 1028.1 FALSE FALSE TRUE 891.7593266 991.3832983 968.0341075 879.8941042 810.1331088 895.3874857 1032.272344 1039.88419 946.3915595 1063.826398 0.838256437 0.931903269 0.90995496 0.827103093 0.761527548 0.841666918 0.970339094 0.977494253 0.8896109 1 10.05504703 -9.424001343 1.040773786 1.00321422 0.876845222 0.018113197 0.072552368 0.56636615 1.051431063 0.054830509 0.012452156 3.77E-10 9.424001343 -0.126368999 WMT(ph)TS(ph)NVMPDNK ddPTM_HeLa_Curcumin_4h_R1 1 WMTTSNVMPDNK 12 0 Q969M7-2 Q969M7-2 2 0 WMT(0.85)T(0.162)S(0.987)NVMPDNK 51.727 0.016761 16014000 1997.6 1669 1567.6 1556.3 1961.5 1849.4 1102 1610.4 2229.7 1726.8 TRUE FALSE FALSE 1839.487852 1813.260923 1625.696635 1549.860443 1938.110394 1465.813593 1132.919154 2101.403547 1985.107488 1786.806171 1.029483713 1.014805608 0.909833792 0.867391476 1.084678587 0.820354002 0.634047034 1.176066873 1.110980878 1 10.80316743 -6.752126694 6.609933107 1.014490348 0.903468322 0.144379914 0.140608378 0.225152708 42.54299101 0.020483716 0.028256093 1.77E-07 6.752126694 -0.111022025 GS(ph)PLAEGPQAFFPER ddPTM_HeLa_Curcumin_4h_R1 2 GSPLAEGPQAFFPER 15 0 Q8WUF5 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 0 GS(1)PLAEGPQAFFPER;GS(1)PLAEGPQAFFPER ; 193.54 1.57E-10 12817000 783.36 692.76 971.33 819.12 925.75 1174.59 1434.19 892.61 729.74 481.33 TRUE FALSE FALSE 721.3562294 752.6390875 1007.328344 815.7306985 914.7110359 930.9667936 1474.429511 1164.76268 649.6893477 498.0561817 1.44834309 1.511152989 2.02251951 1.63782868 1.836561957 1.869200359 2.960367858 2.338617053 1.304449923 1 8.96016468 -1 0.150668527 0.796744929 7.754408976 0.728372584 0.276306574 20.38160522 0.19828582 0.540547977 31.16033375 0.1 1 6.957664047 up WPFSGKTS(ph)PPCSPANLSR ddPTM_HeLa_Curcumin_4h_R1 1 WPFSGKTSPPCSPANLSR 18 1 C9JEJ2;P49585 C9JEJ2 PCYT1A Choline-phosphate cytidylyltransferase A 1 0 WPFS(0.004)GKT(0.39)S(0.567)PPCS(0.038)PANLS(0.002)R 57.248 0.014726 39578000 1443.9 1054.2 1043 1075.5 820.27 1295.7 1093.9 1522.8 1468.4 1489.5 TRUE FALSE FALSE 1329.613791 1145.320351 1081.654498 1071.049866 810.488816 1026.957214 1124.59189 1987.09471 1307.320194 1541.260014 0.862679742 0.74310651 0.701798845 0.69491835 0.525861184 0.666310165 0.729657475 1.289266374 0.848215215 1 10.58989455 -7.841335739 1.045958571 0.96805416 0.745365889 0.079556725 0.193586457 0.528077077 1.218959101 0.048108121 0.042303288 1.44E-08 7.841335739 -0.222688271 WPTETDVSS(ph)AK ddPTM_HeLa_Curcumin_4h_R1 1 WPTETDVSSAK 11 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 1 0 WPTETDVS(0.433)S(0.567)AK 109.15 0.006935 0 1583.6 1422.3 1924.9 1641.2 1741.1 2295.3 1543.9 1103.5 1529.6 1660.9 TRUE FALSE FALSE 1458.256389 1545.237274 1996.238487 1634.409149 1720.33852 1819.228907 1587.217679 1439.95207 1361.806707 1718.616151 0.848506159 0.899117161 1.161538303 0.951003019 1.001002183 1.058542889 0.923544026 0.837855544 0.79238561 1 10.74703164 WPTETDVSSAK ddPTM_HeLa_Curcumin_4h_R1 1 WPTETDVSSAK 11 0 E7EVA0;P27816;P27816-6;P27816-2 E7EVA0 MAP4 Microtubule-associated protein;Microtubule-associated protein 4 0 0 133.23 0.00061975 2348700 1558.4 1445.9 1527.9 1422.7 1968.5 2262.9 1670.3 1485.9 2012 1441.7 FALSE FALSE TRUE 1435.050996 1570.877153 1584.525318 1416.813244 1945.026923 1793.549032 1717.164123 1938.94407 1791.288634 1491.798968 0.961960041 1.053008607 1.062157404 0.9497347 1.303813024 1.202272606 1.151069387 1.299735495 1.200757389 1 10.54283742 -5.76599925 24.99999899 0.992190592 1.230286691 0.538978333 0.084947723 33.38869481 183058.5172 0.007871705 0.014622628 1.71E-06 5.76599925 0.238096099 WQELS(ph)PETSGK ddPTM_HeLa_Curcumin_4h_R1 1 WQELSPETSGK 11 0 Q9NWF9-3;Q9NWF9;Q9NWF9-1 Q9NWF9-3 RNF216 E3 ubiquitin-protein ligase RNF216 1 0 WQELS(0.825)PET(0.124)S(0.051)GK 102.9 0.0093308 4669700 3187 2309.7 2789.5 3007.9 2959.9 3409.6 1771 1295.1 3043.7 2433.2 TRUE FALSE FALSE 2934.745587 2509.340176 2892.881324 2995.454107 2924.605126 2702.410526 1820.689494 1689.970028 2709.813725 2517.753519 1.165620687 0.996658393 1.148993062 1.189732865 1.161593104 1.073341972 0.723140482 0.671221395 1.07628237 1 11.29792134 -4.750397914 4.743414393 1.093553476 0.685436487 0.86531493 0.063927486 0.056286656 3.209392433 0.011182052 0.041185784 1.78E-05 4.750397914 -0.408116989 WQRPS(ph)SPPPFLPAASEEAEPAEGLR ddPTM_HeLa_Curcumin_4h_R1 2 WQRPSSPPPFLPAASEEAEPAEGLR 25 1 H3BLU1;Q4KMQ1-2;Q4KMQ1-4;Q4KMQ1-3;Q4KMQ1 H3BLU1 TPRN Taperin 1 0 WQRPS(0.5)S(0.5)PPPFLPAASEEAEPAEGLR;WQRPS(0.5)S(0.5)PPPFLPAASEEAEPAEGLR ; 56.461 0.0031694 57664000 2920.29 2806.24 2776.64 3399.94 2936.55 3619.8 2887.1 2358.82 3400.6 3005.35 TRUE FALSE FALSE 2689.145965 3048.798881 2879.544721 3385.871949 2901.533559 2869.012676 2968.104256 3078.013359 3027.562688 3109.785689 0.864736748 0.980388743 0.925962433 1.088779835 0.933033286 0.92257569 0.95444013 0.989783113 0.973559914 1 11.60259944 WQRPS(ph)SPPPFLPAASEEAEPAEGLRVPGLAK ddPTM_HeLa_Curcumin_4h_R1 2 WQRPSSPPPFLPAASEEAEPAEGLRVPGLAK 31 2 H3BLU1;Q4KMQ1-2;Q4KMQ1-4;Q4KMQ1-3;Q4KMQ1 H3BLU1 TPRN Taperin 1 0 WQRPS(0.5)S(0.5)PPPFLPAAS(0.001)EEAEPAEGLRVPGLAK;WQRPS(0.5)S(0.5)PPPFLPAASEEAEPAEGLRVPGLAK ; 76.161 8.88E-06 106542000 2727.9 1995.5 2659.4 2755.6 2310.2 3210.6 1908.28 1953.26 3415.6 2827.2 TRUE FALSE FALSE 2511.983837 2167.982128 2757.959703 2744.198057 2282.652374 2544.685369 1961.821201 2548.799982 3040.917225 2925.44499 0.858667261 0.741077729 0.942748783 0.938044662 0.780275268 0.869845572 0.670606081 0.871252063 1.039471683 1 11.51444037 -13.52287874 0.140094255 1.622999241 0.763696843 0.463933835 0.080234162 52.571118 0.512269602 9.006127931 0.226534196 3.00E-14 13.52287874 -0.859302398 WQYDVWST(ph)DVTVANKMEAGGIPGGSK ddPTM_HeLa_Curcumin_4h_R1 1 WQYDVWSTDVTVANKMEAGGIPGGSK 26 1 O60266-2;U3KQ91 O60266-2 ADCY3 1 0 WQY(0.008)DVWS(0.054)T(0.469)DVT(0.469)VANKMEAGGIPGGSK 42.325 0.0085384 0 680.88 323.58 604.38 713.6 553.89 579.79 519.09 532.41 487.55 523.64 TRUE FALSE FALSE 626.9876295 351.5488134 626.7788545 710.6473123 547.2852235 459.5350184 533.6542683 694.7393581 434.0669848 541.836451 1.157152916 0.648809826 1.156767606 1.311553165 1.01005612 0.848106504 0.984899165 1.282193837 0.801103329 1 9.081713641 -9.92138975 2.14756267 0.999312874 1.064497429 0.032417595 0.198747864 1.681392764 14.05042592 0.148147842 0.028253136 1.20E-10 9.92138975 0.065184555 WREEQMER ddPTM_HeLa_Curcumin_4h_R1 2 WREEQMER 8 1 P09496-2;P09496-4;P09496-3;P09496;F8WF69 P09496-2 CLTA Clathrin light chain A 0 0 ; ; 128.12 0.005001 24100700 4148.8 2854.5 3328.7 3522.6 3876.1 4642.9 3514.3 3587.3 4031.9 3824.1 FALSE FALSE TRUE 3820.418102 3101.230261 3452.06455 3508.024415 3829.880039 3679.910204 3612.9018 4681.051256 3589.610657 3956.98719 0.965486598 0.783735229 0.872397201 0.88653924 0.967877796 0.92997779 0.913043592 1.182983677 0.907157513 1 11.95018668 -4.256090952 24.33744242 0.947999975 1.182983823 0.559400595 0.065647453 278.441297 1266956.633 0.010477668 0.119480303 5.55E-05 4.256090952 0.234983848 WS(ph)APESR ddPTM_HeLa_Curcumin_4h_R1 1 WSAPESR 7 0 P54253 P54253 ATXN1 Ataxin-1 1 0 WS(1)APESR 99.013 0.020322 29474000 2753.6 2384.4 2346.5 2598.1 2610 2921.3 2403.2 1833.1 2960.6 2603.8 TRUE FALSE FALSE 2535.649654 2590.496911 2433.463354 2587.349751 2578.877455 2315.38945 2470.627324 2392.003751 2635.829587 2694.281856 0.94112264 0.961479552 0.903195539 0.960311463 0.957166916 0.859371652 0.916989185 0.887807542 0.978305065 1 11.39568507 -6.191190881 0.014561998 1.857730699 2.66E-08 0.577218664 0.026988999 479.1749141 2.666329054 163.3028334 176.7296382 6.44E-07 6.191190881 -1.857730673 WS(ph)DQGPAQTSR ddPTM_HeLa_Curcumin_4h_R1 2 WSDQGPAQTSR 11 0 Q9C0C2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 WS(1)DQGPAQTSR;WS(1)DQGPAQTSR ; 117.48 0.0045275 88763000 3444 3038.3 3098.6 3275.9 3174.7 3870.8 3414.5 2461.82 3379.6 3329.4 TRUE FALSE FALSE 3171.403766 3300.917114 3213.436842 3262.345194 3136.843776 3067.952447 3510.30168 3212.417585 3008.866335 3445.096402 0.920555885 0.958149418 0.932756726 0.946953238 0.910524238 0.890527314 1.018926982 0.932460869 0.873376528 1 11.75032864 -9.397588525 1.017858575 1.001554633 0.938135145 0 0.050787226 0.518672465 0.922788163 0.024692624 0.005706661 4.00E-10 9.397588525 -0.063419488 WS(ph)GNEPTDEFSDLPLR ddPTM_HeLa_Curcumin_4h_R1 1 WSGNEPTDEFSDLPLR 16 0 Q96II8-3;Q96II8;Q96II8-2;E9PD99;Q96II8-4 Q96II8-3 LRCH3 Leucine-rich repeat and calponin homology domain-containing protein 3 1 0 WS(0.99)GNEPT(0.009)DEFS(0.001)DLPLR 125.41 0.00060447 10014000 1362.7 950.65 1121.4 893 1041.1 1772.3 891.34 754.08 953.54 769.56 TRUE FALSE FALSE 1254.840857 1032.81995 1162.96007 889.3050026 1028.685562 1404.705002 916.3486015 983.9955206 848.9390476 796.3021527 1.575835068 1.297020166 1.460450743 1.116793418 1.291828182 1.764035168 1.150754897 1.235706217 1.066101661 1 9.637172148 -9.533168632 1.294665615 1.000104708 1.384747712 0.321312474 0.188175499 0.396554465 1.190823319 0.133508113 0.031902987 2.93E-10 9.533168632 0.384643004 WS(ph)PPQNYK ddPTM_HeLa_Curcumin_4h_R1 1 WSPPQNYK 8 0 H3BRF9;Q96K21-2;Q96K21;H3BRM1;Q96K21-3 H3BRF9;Q96K21-3 ZFYVE19 Abscission/NoCut checkpoint regulator 1 0 WS(1)PPQNYK 97.965 0.016244 111050000 3504.5 3349.5 3588.1 3591 3714.4 4115.7 3478.8 2936 3733.9 3404.8 TRUE FALSE FALSE 3227.115127 3639.015855 3721.078142 3576.141393 3670.108206 3262.057427 3576.405765 3831.172884 3324.300512 3523.116547 0.915983075 1.032896814 1.056189341 1.015050551 1.041722054 0.925901083 1.015125591 1.087438588 0.943568136 1 11.78263649 -7.239869117 24.53844476 0.960325339 1.022190799 0.356807525 0.043706973 656.3094803 746621.7367 0.008204008 0.010042574 5.76E-08 7.239869117 0.06186546 WSDSSKQDDS(ph)PSGASYGQDYDLS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 WSDSSKQDDSPSGASYGQDYDLSPSR 26 1 Q9NYV4-2;J3QSD7;Q9NYV4-3;Q9NYV4 Q9NYV4-2 CDK12 Cyclin-dependent kinase 12 2 0 WSDS(0.008)S(0.032)KQDDS(0.959)PS(0.001)GAS(0.011)YGQDY(0.001)DLS(0.949)PS(0.038)R 97.118 4.54E-06 48699000 3558.1 2652.3 2706 3153.7 3044.4 3500 2459.7 1599.3 3905.5 3007.4 TRUE FALSE FALSE 3276.472631 2881.552994 2806.28674 3140.650825 3008.097518 2774.060547 2528.712562 2086.919208 3477.076421 3111.906926 1.052882592 0.9259766 0.901790062 1.009236748 0.966641223 0.891434292 0.812592607 0.670623916 1.117345892 1 11.6035832 -3.40896293 0.521906232 1.016098997 8.00E-22 0.80286343 0.053620123 2.455587331 0.237095034 0.009554375 1.863825409 0.000389975 3.40896293 -1.016098997 WSGNEPTDEFS(ph)DLPLR ddPTM_HeLa_Curcumin_4h_R1 1 WSGNEPTDEFSDLPLR 16 0 Q96II8-3;Q96II8;Q96II8-2;E9PD99;Q96II8-4 Q96II8-3 LRCH3 Leucine-rich repeat and calponin homology domain-containing protein 3 1 0 WS(0.187)GNEPT(0.194)DEFS(0.619)DLPLR 155.06 0.00031189 4069900 1525.9 1192.1 1447.3 1258 1613.9 2261.6 1271.8 883.35 1279.2 1198.5 TRUE FALSE FALSE 1405.123405 1295.139812 1500.938211 1252.794729 1594.655297 1792.518667 1307.483285 1152.679349 1138.87496 1240.147786 1.133028999 1.044343123 1.210289796 1.010197933 1.285859085 1.445407303 1.054296351 0.929469344 0.918338099 1 10.27629634 -8.96867699 0.427188986 0.971278837 1.160391576 0.190354772 0.142935522 2.827500384 0.809468955 0.235392298 0.049699724 1.07E-09 8.96867699 0.189112739 WSLEDDDDDEDDPAEAEK ddPTM_HeLa_Curcumin_4h_R1 1 WSLEDDDDDEDDPAEAEK 18 0 Q7L014;A0A0C4DG89;D6RJA6 Q7L014 DDX46 Probable ATP-dependent RNA helicase DDX46 0 0 137.68 1.19E-05 0 500.69 644.96 601.75 744.55 553.16 528.6 467.63 610.56 520.57 444.26 FALSE FALSE TRUE 461.0598582 700.7074685 624.0513844 741.4692494 546.5639283 418.9624015 480.7504392 796.7169333 463.4647734 459.6980019 1.002962502 1.524277821 1.357524683 1.612948602 1.188963028 0.91138617 1.045796234 1.733131164 1.008194013 1 8.844542585 -7.292260403 22.46201716 1.001398842 1.316873116 0.293661968 0.236625158 190.2746123 138669.3174 0.041032802 0.046928313 5.10E-08 7.292260403 0.315474274 WTDGSLS(ph)PPAKEPLASDSR ddPTM_HeLa_Curcumin_4h_R1 2 WTDGSLSPPAKEPLASDSR 19 1 O15085;O15085-2 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 1 0 WT(0.029)DGS(0.393)LS(0.578)PPAKEPLAS(0.001)DSR;WT(0.001)DGS(0.156)LS(0.843)PPAKEPLASDSR ; 143.99 7.93E-07 33227000 5267.9 3655.5 4430.1 4572.4 4312.1 4997.1 3809.3 4773.3 5388.5 4406.2 TRUE FALSE FALSE 4850.940156 3971.465131 4594.283403 4553.48062 4260.681024 3960.645131 3916.178706 6228.657196 4797.395031 4559.315122 1.063962465 0.871066163 1.007669635 0.998720312 0.934500229 0.868693 0.858940126 1.36613878 1.052218349 1 12.15460141 WTPY(ph)PS(ph)QKTLDLQS(ph)GLKDITGNK ddPTM_HeLa_Curcumin_4h_R1 1 WTPYPSQKTLDLQSGLKDITGNK 23 2 H3BSS6;Q9H2Y7;H3BNX5 H3BSS6 ZNF106 Zinc finger protein 106 3 0 WT(0.267)PY(0.722)PS(0.75)QKT(0.275)LDLQS(0.946)GLKDIT(0.041)GNK 49.188 0.012194 23856000 801.49 910.78 1153 1064.7 1280.5 1529.1 1193.1 1015 1340.9 850.76 TRUE FALSE FALSE 738.0512208 989.5037648 1195.731194 1060.294554 1265.230874 1211.947423 1226.575175 1324.468828 1193.806625 880.3238467 0.838386037 1.124022448 1.358285589 1.204436933 1.437233444 1.376706343 1.393322673 1.504524537 1.356099382 1 9.781890539 -6.921133862 2.624789433 0.92385031 1.378647291 0.382258843 0.158839836 0.075692814 1.060132197 0.015612308 0.020865183 1.20E-07 6.921133862 0.454796981 WVKT(ph)MEVY(ph)PY(ph)LPHVVNQGT(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 WVKTMEVYPYLPHVVNQGTR 20 1 P60509 P60509 ERVPABLB-1 Endogenous retrovirus group PABLB member 1 Env polyprotein;Surface protein domain;Transmembrane protein domain 4 0 WVKT(1)MEVY(1)PY(1)LPHVVNQGT(1)R 40.047 0.019704 7038200 3116.9 2479.3 2398.1 2754.7 2686.8 3757.9 3037 2547.9 3106.4 2716.7 TRUE FALSE FALSE 2870.194076 2693.599644 2486.975696 2743.301781 2654.761665 2978.46918 3122.210046 3324.742981 2765.635692 2811.105123 1.021019831 0.958199543 0.884696796 0.975880183 0.944383632 1.059536748 1.110669971 1.182717414 0.983825069 1 11.45692169 -4.752669181 1.977070245 0.990347284 1.173889101 0.744006633 0.041456524 0.176575469 1.25443791 0.006897762 0.041220779 1.77E-05 4.752669181 0.183541817 QPAQELSPT(ph)PGGTAHQALK ddPTM_HeLa_Curcumin_4h_R1 2 QPAQELSPTPGGTAHQALK 19 0 I3L2J8;Q9UPN4-3;Q9UPN4-2;Q9UPN4 I3L2J8 CEP131 Centrosomal protein of 131 kDa 1 0 QPAQELS(0.313)PT(0.687)PGGTAHQALK;QPAQELS(0.352)PT(0.645)PGGT(0.003)AHQALK ; 155.88 9.11E-05 29100900 4513.9 4317.5 4066.7 3672.3 3602 4357.4 3095 1615.62 4971.1 4696.2 TRUE FALSE FALSE 4156.620052 4690.685462 4217.415479 3657.104996 3559.048503 3453.626122 3181.83737 2108.215101 4425.782767 4859.3926 0.85537852 0.965282258 0.867889431 0.752584797 0.732406042 0.710711483 0.654780881 0.433843337 0.910768718 1 12.24656028 -3.8313281 0.309858051 0.967079249 1.98E-19 0.892700751 0.052396039 2.296979387 0.130221198 0.023588042 0.879803974 0.000147459 3.8313281 -0.967079249 down Y(ph)DS(ph)VS(ph)VFNGAVSDDSRR ddPTM_HeLa_Curcumin_4h_R1 2 YDSVSVFNGAVSDDSRR 17 1 Q15113 Q15113 PCOLCE Procollagen C-endopeptidase enhancer 1 3 0 Y(1)DS(1)VS(1)VFNGAVSDDSRR;Y(1)DS(1)VS(1)VFNGAVSDDSRR ; 59.513 0.011809 74819000 10405.8 9353.1 8753.2 8829.5 9137 10830.8 7738.3 8404.5 10132.8 8949.8 TRUE FALSE FALSE 9582.16995 10161.54029 9077.601292 8792.965869 9028.047243 8584.369992 7955.415871 10966.99336 9021.257191 9260.804884 1.034701634 1.097263188 0.980217314 0.949481819 0.97486637 0.926957224 0.859041517 1.184237601 0.974133167 1 13.17692187 -6.545982791 24.98193818 1.023664277 0.968715867 0.065367683 0.083175474 404.0418992 436880.615 0.011961864 0.016917243 2.84E-07 6.545982791 -0.05494841 Y(ph)EHVLEALNDY(ph)KT(ph)MFMS(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 YEHVLEALNDYKTMFMSGK 19 1 Q9Y483-3;Q9Y483 Q9Y483-3 MTF2 Metal-response element-binding transcription factor 2 4 0 Y(1)EHVLEALNDY(1)KT(1)MFMS(1)GK 42.325 0.015367 20286000 2816.1 2858.6 3172 2687.9 3056.5 3182.8 2360.8 2389.7 3244.6 2806.2 TRUE FALSE FALSE 2593.202713 3105.684646 3289.55711 2676.778182 3020.053234 2522.651402 2427.037694 3118.308529 2888.675498 2903.715241 0.893063713 1.069555514 1.132878687 0.921845966 1.040065221 0.868766801 0.835838742 1.073903007 0.994820517 1 11.50368426 -3.940248564 18.95580142 0.961691147 2.597436436 0.09067729 0.089676441 174.0902106 86942.81769 0.012599349 6647.339632 0.00011475 3.940248564 1.635745289 Y(ph)ILDGISALRK ddPTM_HeLa_Curcumin_4h_R1 1 YILDGISALRK 11 1 C9J5B0;B5MCZ3;B5MC14;P05231 C9J5B0 IL6 Interleukin-6 1 0 Y(1)ILDGISALRK 112.36 0.0049243 43034000 4213.3 3729.2 3897.2 4196.4 3780 4832.5 3975.1 3981.6 4631.7 3658.4 TRUE FALSE FALSE 3879.812859 4051.535431 4041.63366 4179.036409 3734.925969 3830.185027 4086.630608 5195.571511 4123.614098 3785.529128 1.024906355 1.070269253 1.067653563 1.103950404 0.986632474 1.011796475 1.07954013 1.372482244 1.089309832 1 11.88627925 -4.260496918 3.042597779 1.025141987 1.428421448 0.848649644 0.040663979 0.091780922 1.249097087 0.005473363 0.089121308 5.49E-05 4.260496918 0.403279461 Y(ph)LDQIGNMT(ph)S(ph)SQRRS(ph)KK ddPTM_HeLa_Curcumin_4h_R1 1 YLDQIGNMTSSQRRSKK 17 3 Q8WWI1-3;E9PMS6;Q8WWI1;Q8WWI1-4;Q8WWI1-2;J3KP06;F8WD26;Q8WWI1-5;E9PMT2;A0A0A0MTE2 Q8WWI1-3 LMO7 LIM domain only protein 7 4 0 Y(1)LDQIGNMT(0.999)S(0.999)S(0.023)QRRS(0.98)KK 60.55 0.008647 4667900 2508 1993.5 2583.1 2278.4 2878 3044 2508.8 2170.5 2156.6 2334.6 TRUE FALSE FALSE 2309.489154 2165.809257 2678.831958 2268.972584 2843.68173 2412.640087 2579.190176 2832.275458 1920.026376 2415.727176 0.956022342 0.89654547 1.108913285 0.939250345 1.177153512 0.998722087 1.067666167 1.17243184 0.794802656 1 11.23824182 -6.043163534 1.210594661 0.975580044 1.093758152 0.340735413 0.094252276 0.389624941 1.129473427 0.011576294 0.02605991 9.05E-07 6.043163534 0.118178108 Y(ph)LEENVMRHFALDAAATVAAQR ddPTM_HeLa_Curcumin_4h_R1 1 YLEENVMRHFALDAAATVAAQR 22 1 A6NP16;E7ERM3;Q4VCS5-2;Q4VCS5 A6NP16 AMOT Angiomotin 1 0 Y(1)LEENVMRHFALDAAATVAAQR 45.436 0.01524 94159000 779.65 841.61 937.71 1081 814.34 1284.6 862.54 595.64 1063.2 949.51 TRUE FALSE FALSE 717.9398798 914.3550183 972.4623575 1076.527108 804.6295274 1018.15948 886.740551 777.247894 946.56962 982.5054018 0.730723595 0.930636123 0.989778128 1.095695867 0.818956848 1.036288938 0.90252995 0.791087655 0.963424342 1 9.940321529 -7.025194748 24.80101796 0.870622656 0.944870771 0.007719448 0.109243246 1501.658427 1478188.873 0.021309633 0.026161411 9.44E-08 7.025194748 0.074248116 Y(ph)LFDVS(ph)MLS(ph)DK ddPTM_HeLa_Curcumin_4h_R1 1 YLFDVSMLSDK 11 0 A0PK22;A0A087X0X2;Q6KF10 A0PK22 GDF6 Growth/differentiation factor 6 3 0 Y(1)LFDVS(1)MLS(1)DK 57.175 0.0090096 0 2945.7 2579 2610.4 2759.1 2555.7 2988.2 2814.5 1989.3 2881.6 2827.3 TRUE FALSE FALSE 2712.544737 2801.917268 2707.14372 2747.683575 2525.224947 2368.413636 2893.467295 2595.828412 2565.495689 2925.548465 0.927191865 0.957740848 0.92534571 0.939202891 0.863162917 0.809562263 0.989034135 0.887296329 0.876928111 1 11.5144914 -9.051832401 0.248093333 1.045368052 0.887386447 0 0.059309443 3.976964558 0.394061993 0.20047371 0.04688864 8.87E-10 9.051832401 -0.157981605 LGSPDTVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 LGSPDTVSPR 10 0 H0Y9Y2 H0Y9Y2 BOD1L1 1 0 LGSPDTVS(1)PR;LGSPDTVS(1)PR ; 133.91 0.0023664 67230000 5654 4572.6 4474.2 5061 4774.6 6004.7 3899.1 1982.7 6394.3 5391.4 TRUE FALSE FALSE 5206.479934 4967.835169 4640.017788 5040.058923 4717.666013 4759.257533 4008.498252 2587.216103 5692.861288 5578.750749 0.933269861 0.890492405 0.831730614 0.903438628 0.845649183 0.85310453 0.718529727 0.463762627 1.020454497 1 12.44572638 -3.830601714 0.556246338 0.958244706 1.36E-43 0.872927327 0.054020993 1.427877892 0.213982542 0.010730554 0.98265839 0.000147706 3.830601714 -0.958244706 down Y(ph)LLGDAPVSPSSQK ddPTM_HeLa_Curcumin_4h_R1 1 YLLGDAPVSPSSQK 14 0 Q9NYB0;A0A590UJT3;H3BMI8 Q9NYB0 TERF2IP Telomeric repeat-binding factor 2-interacting protein 1 1 0 Y(0.855)LLGDAPVS(0.14)PS(0.004)S(0.001)QK 141.88 0.0044616 88427000 8443.3 6749.4 7339.8 7243.2 7723.3 9112.3 6089.5 4526.2 8182.9 7630.2 TRUE FALSE FALSE 7775.003896 7332.788061 7611.819445 7213.229558 7631.204692 7222.306263 6260.354981 5906.217544 7285.256343 7895.348882 0.984757483 0.92874782 0.964089055 0.913604917 0.96654433 0.914754544 0.792916827 0.748062895 0.922727602 1 12.9467873 -2.920205474 0.433162142 0.991942016 4.82E-14 0.796111075 0.035023271 2.955584207 0.155930687 0.006354266 1.956699044 0.001201696 2.920205474 -0.991942016 Y(ph)LY(ph)RDVMLENYMNLASVDK ddPTM_HeLa_Curcumin_4h_R1 1 YLYRDVMLENYMNLASVDK 19 1 F8W7U5 F8W7U5 ZNF561 2 0 Y(1)LY(1)RDVMLENYMNLASVDK 58.671 0.0058813 0 620.55 479.92 617.39 490.32 710.01 726.8 643.97 535.89 898.57 655.57 TRUE FALSE FALSE 571.4328127 521.4021463 640.2710165 488.2911858 701.5435945 576.0534873 662.038065 699.2803941 799.9991191 678.3510087 0.842385145 0.768631784 0.943863882 0.719820829 1.034189653 0.849196773 0.975952061 1.030853327 1.179329151 1 9.40588817 -4.559360333 5.568395279 0.903199297 1.018983707 0.066718668 0.127659778 0.227418816 18.13213331 0.013747356 0.056433977 2.76E-05 4.559360333 0.11578441 Y(ph)MDPS(ph)T(ph)YQVLS(ph)NLK ddPTM_HeLa_Curcumin_4h_R1 1 YMDPSTYQVLSNLK 14 0 Q96G79 Q96G79 SLC35A4 Probable UDP-sugar transporter protein SLC35A4 4 0 Y(0.999)MDPS(0.973)T(0.565)Y(0.479)QVLS(0.985)NLK 49.188 0.017615 9515400 2224.8 2120.4 2130.7 2383.5 2277.3 2504.6 2247.6 1802.6 2428.9 2302.8 TRUE FALSE FALSE 2048.704732 2303.677928 2209.665616 2373.637709 2250.144685 1985.117727 2310.661607 2352.204442 2162.455747 2382.822129 0.859780807 0.966785519 0.927331331 0.99614557 0.944319199 0.833095221 0.969716362 0.987150662 0.907518745 1 11.21845555 -4.540805137 24.98318304 0.933042731 0.982792231 0.130663441 0.050784725 391.5869627 545736.7222 0.008530707 0.031930339 2.88E-05 4.540805137 0.0497495 Y(ph)MEDSTYY(ph)KAS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 YMEDSTYYKASK 12 1 Q05397-5;Q05397;Q05397-7;Q05397-2;E7ESA6;H0YBP1;H0YB16;H0YBZ1;E9PEI4;Q05397-3 Q05397-5 PTK2 Focal adhesion kinase 1 3 0 Y(0.975)MEDS(0.205)T(0.205)Y(0.23)Y(0.519)KAS(0.866)K 41.48 0.0094623 0 778.68 1247.5 997.59 1050.8 907.44 846.78 733.63 707.63 1437.1 1225.7 TRUE FALSE FALSE 717.0466563 1355.328341 1034.561563 1046.452068 896.6193707 671.1482828 754.2136833 923.3831295 1279.453725 1268.292984 0.565363576 1.068624016 0.815711808 0.825087012 0.706949721 0.529174482 0.59466834 0.72805191 1.008799813 1 10.30867234 -5.572123653 3.854002049 0.816158788 0.614397139 0.354039138 0.147880922 0.274717276 8.523947811 0.026450738 0.056420724 2.68E-06 5.572123653 -0.20176165 Y(ph)NLDASEEEDSNK ddPTM_HeLa_Curcumin_4h_R1 1 YNLDASEEEDSNK 13 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 Y(0.696)NLDAS(0.304)EEEDS(0.001)NK 96.171 0.0049394 0 752.32 762.34 1035 920.35 990.32 997.99 795.91 1069.2 714.79 799.64 TRUE FALSE FALSE 692.7730782 828.2332727 1073.35801 916.5418356 978.5110808 790.9956243 818.2410925 1395.194158 636.3793253 827.4274305 0.837261435 1.000973913 1.297223141 1.107700569 1.182594442 0.955969787 0.988897712 1.68618311 0.769105908 1 9.692488976 -6.942161957 6.356925634 0.92287252 1.17607012 0.352262889 0.200038953 0.198423215 16.34593982 0.030552511 0.040193213 1.14E-07 6.942161957 0.2531976 Y(ph)NLT(ph)LENNS(ph)GS(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 YNLTLENNSGSK 12 0 A0A0A0MRA3;A0A0A0MTS7;Q8WZ42-3;Q8WZ42-10;Q8WZ42-9;Q8WZ42-5;Q8WZ42-11;Q8WZ42-4;Q8WZ42-7;Q8WZ42-2;Q8WZ42;Q8WZ42-8;Q8WZ42-13;Q8WZ42-12 A0A0A0MRA3 TTN Titin 4 0 Y(1)NLT(1)LENNS(1)GS(1)K 49.621 0.0094717 0 503.32 386.25 317.19 506.57 381.59 436.51 493.41 526.59 585.58 621.6 TRUE FALSE FALSE 463.4816909 419.6357289 328.9453404 504.4739476 377.0397885 345.9729055 507.2537567 687.1448669 521.343339 643.2005537 0.720586586 0.652418171 0.511419554 0.784318273 0.586193196 0.537892736 0.788640112 1.068321324 0.810545538 1 9.329124838 -8.879601169 0.798299463 0.99493239 0.694455399 0.159489792 0.161193524 0.53532684 0.64695183 0.09118707 0.03198265 1.32E-09 8.879601169 -0.300476992 Y(ph)NPNVLPVQCT(ph)GK ddPTM_HeLa_Curcumin_4h_R1 1 YNPNVLPVQCTGK 13 0 P05026-2;P05026 P05026-2 ATP1B1 Sodium/potassium-transporting ATPase subunit beta-1 2 0 Y(1)NPNVLPVQCT(1)GK 117.53 0.014087 27975000 11094 8989.4 9526.4 10545 9161.9 13190 10541 9634.9 11542 9798 TRUE FALSE FALSE 10215.89819 9766.40368 9879.456764 10501.36758 9052.650326 10454.24532 10836.75209 12572.53666 10275.87148 10138.47977 1.007636098 0.963300603 0.974451494 1.035793119 0.892900172 1.031145256 1.068873474 1.240081052 1.01355151 1 13.30755372 -4.263771253 1.821822363 0.994215869 1.319159825 0.797428367 0.038496756 0.268083996 0.889212351 0.005164095 0.148574077 5.45E-05 4.263771253 0.324943956 Y(ph)QRLS(ph)ETCT(ph)FAK ddPTM_HeLa_Curcumin_4h_R1 1 YQRLSETCTFAK 12 1 A1A5B4 A1A5B4 ANO9 Anoctamin-9 3 0 Y(1)QRLS(1)ET(0.027)CT(0.974)FAK 49.223 0.020356 4246800 4567.7 3729.6 4249.2 4420.4 4911 5196.3 4169.5 4303 4562.7 4132.9 TRUE FALSE FALSE 4206.161725 4051.970005 4406.67909 4402.109556 4852.439532 4118.528806 4286.484948 5614.964891 4062.183225 4276.517967 0.983548241 0.947492805 1.030436239 1.029367722 1.134670676 0.963056589 1.00233063 1.312975868 0.949881014 1 12.06222089 -4.261445611 13.01253205 1.002178496 1.313098993 0.762190654 0.051671888 0.019079173 499.7184902 0.006760686 0.052000113 5.48E-05 4.261445611 0.310920496 Y(ph)QT(ph)KEPVT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 YQTKEPVTK 9 1 Q3SYA6;Q8TD91-2;Q8TD91 Q3SYA6 MAGEC3 Melanoma-associated antigen C3 3 0 Y(1)QT(1)KEPVT(1)K 58.098 0.018567 1395200 1482.6 1324.5 1746.3 1720.6 1576.7 2487.7 1676.1 1340.5 1773.1 1736.2 TRUE FALSE FALSE 1365.250646 1438.983878 1811.019414 1713.480613 1557.898882 1971.722978 1723.126855 1749.212279 1578.595366 1796.532821 0.759936378 0.800978341 1.00806364 0.953770838 0.867169731 1.097515701 0.959140203 0.973660074 0.878689968 1 10.81099958 -6.744994105 24.97039302 0.877044739 0.975252598 0.33295958 0.079405001 333.9116621 507007.9969 0.016798452 0.023716956 1.80E-07 6.744994105 0.098207859 Y(ph)RCS(ph)SNLVLTGS(ph)S ddPTM_HeLa_Curcumin_4h_R1 2 YRCSSNLVLTGSS 13 1 A0A0G2JJM0 A0A0G2JJM0 3 0 Y(0.988)RCS(0.885)S(0.127)NLVLT(0.015)GS(0.613)S(0.372);Y(0.993)RCS(0.916)S(0.091)NLVLT(0.018)GS(0.583)S(0.4) ; 78.228 0.010051 4631700 3299.2 2644.6 3054 3280.6 2431.3 4031.2 3016.7 3862.2 3591 2982.4 TRUE FALSE FALSE 3038.064839 2873.18744 3167.183927 3267.025746 2402.308335 3195.083679 3101.340483 5039.767001 3197.076284 3086.038178 0.984454716 0.931027834 1.026294473 1.058647223 0.77844414 1.035335111 1.00495856 1.633086407 1.035980795 1 11.59154019 -4.25995685 5.313952975 0.98332218 1.66017409 0.867504315 0.076157383 0.036070051 3.593956199 0.009482133 0.088597382 5.50E-05 4.25995685 0.67685191 Y(ph)RFQLQAT(ph)T(ph)K ddPTM_HeLa_Curcumin_4h_R1 2 YRFQLQATTK 10 1 P32004-3;P32004-2;P32004 P32004-3 L1CAM Neural cell adhesion molecule L1 3 0 Y(1)RFQLQAT(1)T(1)K;Y(1)RFQLQAT(1)T(1)K ; 62.463 0.016227 3501800000 8399.7 16270.6 11452.7 9933.5 7094 10061 11335.9 7583.5 11707.3 16671.9 TRUE FALSE FALSE 7734.854882 17676.95816 11877.14714 9892.397809 7009.408683 7974.235189 11653.95484 9895.67424 10423.03848 17251.24728 0.448364965 1.024677107 0.688480487 0.573430874 0.406313153 0.462241081 0.675542739 0.573620798 0.604190428 1 14.07441305 -6.298007427 3.803232992 0.757042956 0.532173287 0.287358547 0.171748509 0.311033949 9.711416285 0.035165886 0.056296182 5.03E-07 6.298007427 -0.224869669 Y(ph)RGDTSQAADDSASTT(ph)GSRK ddPTM_HeLa_Curcumin_4h_R1 1 YRGDTSQAADDSASTTGSRK 20 2 Q9Y2K1-2;Q9Y2K1 Q9Y2K1-2 ZBTB1 Zinc finger and BTB domain-containing protein 1 2 0 Y(0.59)RGDT(0.205)S(0.205)QAADDS(0.036)AS(0.241)T(0.165)T(0.429)GS(0.13)RK 45.82 0.018317 7635800 1943.1 1311.4 1958.4 1950.3 1779.2 1900.3 1534.5 1391.8 2115.1 1751.8 TRUE FALSE FALSE 1789.301585 1424.751573 2030.980027 1942.230175 1757.984202 1506.156359 1577.55394 1816.153413 1883.078822 1812.67492 0.987105611 0.785993979 1.120432574 1.071471864 0.969828723 0.830902631 0.870290598 1.001918984 1.038839784 1 10.8239045 -5.501818658 23.23730304 0.992986465 0.898363171 0.189118571 0.091376944 396.4442464 437427.3642 0.012542465 0.027725256 3.15E-06 5.501818658 -0.094623294 Y(ph)RIQEQESS(ph)GEEDSDLSPEER ddPTM_HeLa_Curcumin_4h_R1 1 YRIQEQESSGEEDSDLSPEER 21 1 E7EMN6;Q6NXS1;P41236 E7EMN6 PPP1R2;PPP1R2P3 Protein phosphatase inhibitor 2-like protein 3;Protein phosphatase inhibitor 2 2 0 Y(0.994)RIQEQES(0.061)S(0.939)GEEDS(0.003)DLS(0.003)PEER 84.602 0.0017567 35875000 962.56 1010.8 1122.5 940.41 1031.8 1479.6 946.22 864.24 1335.3 1040.3 TRUE FALSE FALSE 886.3723603 1098.169048 1164.100837 936.5188326 1019.496459 1172.714281 972.7683866 1127.742798 1188.820931 1076.450348 0.8234215 1.020176221 1.081425483 0.870006531 0.947091021 1.089427194 0.903681613 1.04764962 1.104389936 1 10.07206606 -7.216386151 24.99983897 0.916615626 0.991154039 0 0.098492429 687.6404971 381569.2266 0.015091585 0.018483297 6.08E-08 7.216386151 0.074538413 Y(ph)RNMGDIWRS(ph)NFR ddPTM_HeLa_Curcumin_4h_R1 1 YRNMGDIWRSNFR 13 2 H7C4S9 H7C4S9 KCNAB1 2 0 Y(1)RNMGDIWRS(1)NFR 65.157 0.020089 65445000 5853.7 4452.3 5143.6 5770.8 5449.8 6787.3 5702.7 3823.2 6732.1 6079.7 TRUE FALSE FALSE 5390.373468 4837.136973 5334.226341 5746.921959 5384.814694 5379.537471 5862.702414 4988.87608 5993.605473 6290.969122 0.856843097 0.768901719 0.847918061 0.91351934 0.855959486 0.855120629 0.931923572 0.793021867 0.952731663 1 12.61906657 -9.022587124 0.856897382 0.998656637 0.855835846 0.507119971 0.047678757 0.330579503 0.448754172 0.028731376 0.009173939 9.49E-10 9.022587124 -0.14282079 Y(ph)RQEILT(ph)ALDRDASCRK ddPTM_HeLa_Curcumin_4h_R1 1 YRQEILTALDRDASCRK 17 3 P51805 P51805 PLXNA3 Plexin-A3 2 0 Y(1)RQEILT(1)ALDRDASCRK 68.283 0.0082754 131890000 2362.8 1903.8 2141.6 2263.3 2476.3 3297 2536.8 2046.9 2455 2078.8 TRUE FALSE FALSE 2175.781887 2068.355989 2220.96958 2253.935064 2446.77174 2613.165035 2607.975781 2670.990387 2185.692642 2151.038145 1.011503163 0.961561743 1.032510551 1.047835934 1.137484124 1.214839003 1.212426561 1.241721535 1.016110591 1 11.07081739 -5.631104161 1.414170825 1.002612431 1.23115711 0.969709191 0.017149171 0.044542814 0.176222772 0.00253063 0.007076089 2.34E-06 5.631104161 0.228544679 Y(ph)RYPGSLDESQMAK ddPTM_HeLa_Curcumin_4h_R1 2 YRYPGSLDESQMAK 14 1 Q00973-2;Q00973 Q00973-2 B4GALNT1 "Beta-1,4 N-acetylgalactosaminyltransferase 1" 1 0 Y(0.535)RY(0.342)PGS(0.123)LDESQMAK;Y(0.474)RY(0.474)PGS(0.052)LDESQMAK ; 54.023 0.017929 23617400 9808.7 13418.5 15365.1 13529 6163.7 5779.2 9502.4 7349.4 9508.4 18484.9 TRUE FALSE FALSE 9032.331045 14578.33535 15934.54412 13473.02058 6090.201903 4580.528775 9769.01177 9590.198228 8465.352309 19127.2489 0.472223219 0.762176277 0.833080816 0.704388836 0.318404489 0.239476613 0.510737944 0.501389315 0.442580758 1 14.22334176 -5.821406585 6.060395353 0.751220403 0.390373474 0.421749097 0.172560501 0.153436897 11.140726 0.031069602 0.057244847 1.51E-06 5.821406585 -0.360846929 Y(ph)S(ph)GSY(ph)NDY(ph)LR ddPTM_HeLa_Curcumin_4h_R1 1 YSGSYNDYLR 10 0 Q96PK6 Q96PK6 RBM14 RNA-binding protein 14 4 0 Y(0.988)S(0.99)GS(0.471)Y(0.551)NDY(0.999)LR 48.004 0.0091164 0 0 0 59.817 0 0 0 0 0 0 0 TRUE FALSE FALSE 0 0 62.03387064 0 0 0 0 0 0 0 0 Y(ph)S(ph)T(ph)KS(ph)NLTVHRK ddPTM_HeLa_Curcumin_4h_R1 1 YSTKSNLTVHRK 12 2 Q5SVQ8-2;Q5SVQ8 Q5SVQ8-2 ZBTB41 Zinc finger and BTB domain-containing protein 41 4 0 Y(1)S(1)T(0.997)KS(0.997)NLT(0.006)VHRK 50.305 0.0191 6492000 3547.7 4174.7 3487.1 3582.4 3394.5 2513.4 2667.8 1852.4 4142.1 3295.1 TRUE FALSE FALSE 3266.895801 4535.542466 3616.334994 3567.576978 3354.022805 1992.092508 2742.651288 2417.188233 3687.721993 3409.60448 0.958145093 1.330225395 1.060631817 1.04633162 0.983698498 0.584259119 0.804389865 0.708935082 1.081568849 1 11.73538868 -5.355191866 6.237448589 1.019293909 0.710819533 0.668711144 0.115093128 0.124107025 6.834816912 0.017177441 0.038808435 4.41E-06 5.355191866 -0.308474376 Y(ph)T(ph)FHDREEVVK ddPTM_HeLa_Curcumin_4h_R1 1 YTFHDREEVVK 11 1 Q9C0G6-4;Q9C0G6 Q9C0G6-4 DNAH6 "Dynein heavy chain 6, axonemal" 2 0 Y(1)T(1)FHDREEVVK 96.665 0.018809 11428000 3419.7 2836.2 3182.3 3110.3 3560.7 4687.4 4010.7 2840.7 3804.1 3156.2 TRUE FALSE FALSE 3149.027137 3081.34849 3300.238837 3097.430403 3518.240978 3715.180402 4123.229448 3706.816353 3386.799747 3265.877715 0.964220773 0.943497816 1.010521252 0.948422039 1.077272723 1.137574865 1.262518014 1.135013824 1.037025891 1 11.67325506 -5.378144614 2.053980212 0.979513259 1.196780481 0.809158113 0.042360109 0.079874201 0.650879404 0.005242417 0.014767018 4.19E-06 5.378144614 0.217267222 Y(ph)VKDDK ddPTM_HeLa_Curcumin_4h_R1 1 YVKDDK 6 1 A0A1W2PNZ9;Q15652-3;Q15652;Q15652-2;H7BXU7 A0A1W2PNZ9 JMJD1C Probable JmjC domain-containing histone demethylation protein 2C 1 0 Y(1)VKDDK 208.74 8.26E-06 173060000 4612.7 3621.4 3867.4 4135.3 4521.2 5018.2 4242.6 3608.6 3807.2 3664.7 TRUE FALSE FALSE 4247.599928 3934.417679 4010.729246 4118.189224 4467.287643 3977.368753 4361.635938 4708.845528 3389.559685 3792.048052 1.120133466 1.037544257 1.05766836 1.086006603 1.178067256 1.048870874 1.150205872 1.241768423 0.893859898 1 11.88876153 -1 0.056193408 0.837757426 1.640941391 0.535260715 0.063462132 242.0211436 1.030849709 3.217343872 16.3144148 0.1 1 0.803183965 Y(ph)VLGYKQT(ph)LKMIR ddPTM_HeLa_Curcumin_4h_R1 1 YVLGYKQTLKMIR 13 2 P62888;A0A0C4DH44;E5RI99;E5RJH3 P62888 RPL30 60S ribosomal protein L30 2 0 Y(1)VLGY(0.003)KQT(0.997)LKMIR 62.287 0.016992 23479000 2241.8 1501.2 1733.9 1813.1 1631.7 1848.1 1478.9 1316.8 1755.6 1279.9 TRUE FALSE FALSE 2064.359164 1630.957039 1798.159859 1805.597873 1612.243043 1464.783228 1520.393954 1718.286258 1563.015072 1324.37643 1.55874049 1.231490536 1.357740759 1.363356997 1.217360115 1.106017288 1.148007409 1.297430413 1.180189436 1 10.37109752 -5.531720398 23.06548633 1.281700855 1.177145828 0.09030058 0.142041707 202.6290714 528603.1752 0.030767904 0.061635091 2.94E-06 5.531720398 -0.104555028 Y(ph)VY(ph)YGKNS(ph)EGNR ddPTM_HeLa_Curcumin_4h_R1 1 YVYYGKNSEGNR 12 1 M0R2H0;A0A087WWI0;Q9H2I8 M0R2H0 C10orf11 Leucine-rich repeat-containing protein C10orf11 3 0 Y(0.999)VY(0.886)Y(0.115)GKNS(1)EGNR 68.846 0.0075822 0 466.15 240.12 400.35 526.32 314.93 421.67 327.96 195.46 412.03 337.71 TRUE FALSE FALSE 429.2537356 260.8749028 415.1873232 524.1422273 311.1746654 334.2108888 337.1616749 255.0548542 366.8313398 349.4453974 1.228385719 0.746539817 1.188132184 1.499925972 0.890481511 0.956403751 0.964847949 0.729884715 1.049752959 1 8.448923234 Y(ph)Y(ph)ERQQSDLDK ddPTM_HeLa_Curcumin_4h_R1 1 YYERQQSDLDK 11 1 E9PNN2;Q6TCH8;E9PMB9;Q16798-2;Q16798 E9PNN2 ME3 "Malic enzyme;NADP-dependent malic enzyme, mitochondrial" 2 0 Y(1)Y(1)ERQQS(0.001)DLDK 55.806 0.019272 24404000 7785.6 7088.3 6545.1 8113.5 7550.6 8675.5 6789.1 4288.7 8730.6 6751.7 TRUE FALSE FALSE 7169.361545 7700.981067 6787.667164 8079.928487 7460.564026 6876.103507 6979.583874 5596.304887 7772.875023 6986.321072 1.026199837 1.102294181 0.971565305 1.156535522 1.067881643 0.984223805 0.999035659 0.80103746 1.112584856 1 12.77031723 -4.018984894 1.720005146 1.029413671 0.587294588 0.593520934 0.060039353 1.010937609 1.732130422 0.007796427 0.891958128 9.57E-05 4.018984894 -0.442119083 Y(ph)Y(ph)RMMQTVRRMELK ddPTM_HeLa_Curcumin_4h_R1 1 YYRMMQTVRRMELK 14 3 P08559-3;P08559;P08559-2;P08559-4;Q5JPU0;Q5JPT9;Q5JPU1;Q5JPU2 P08559-3 PDHA1 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial" 2 0 Y(0.999)Y(0.999)RMMQT(0.001)VRRMELK 43.297 0.0096773 0 732.55 529.06 331.41 578.07 648.19 455.36 501.88 211.24 487.62 478.9 TRUE FALSE FALSE 674.5678945 574.789589 343.6923461 575.6780995 640.4607576 360.913203 515.9614021 275.6461036 434.129306 495.5417394 1.361273614 1.159921644 0.693568914 1.161714652 1.292445634 0.728320491 1.041206746 0.55625204 0.87607011 1 8.95286277 -3.828765858 0.646729225 1.148601963 2.64E-15 0.233224122 0.222867852 4.433699883 0.86988052 0.039075802 4.270647781 0.000148332 3.828765858 -1.148601963 Y(ph)YSDS(ph)DDELTVEQR ddPTM_HeLa_Curcumin_4h_R1 1 YYSDSDDELTVEQR 14 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 2 0 Y(0.769)Y(0.003)S(0.222)DS(0.841)DDELT(0.164)VEQR 132.24 0.0002323 0 2345.3 2052.5 1544.8 1988.9 1861.4 2157.9 2022.8 1518.7 2514.6 1973.1 TRUE FALSE FALSE 2159.66703 2229.908954 1602.051647 1980.670459 1839.204021 1710.327215 2079.554324 1981.744639 2238.754671 2041.665078 1.057796919 1.092201154 0.784678968 0.970125061 0.900835323 0.837711941 1.018558012 0.970651191 1.096533753 1 10.99553051 -6.78723647 24.99999467 1.032923697 0.917041349 0.498892235 0.070239515 163.7234294 158663.976 0.010827163 0.01423235 1.63E-07 6.78723647 -0.115882348 IPEPES(ph)PAKPNVPTASTAPPADSR ddPTM_HeLa_Curcumin_4h_R1 1 IPEPESPAKPNVPTASTAPPADSR 24 1 Q9BZL4-5;Q9BZL4-2;Q9BZL4-4;Q9BZL4;K7EL81;Q9BZL4-3;K7ER83 Q9BZL4-5 PPP1R12C Protein phosphatase 1 regulatory subunit 12C 1 0 IPEPES(0.952)PAKPNVPT(0.014)AS(0.016)T(0.016)APPADS(0.001)R 48.224 0.013548 17879000 905.2 691.09 924.35 799.72 1048.5 1160.7 1182 1449.4 978.9 582.06 TRUE FALSE FALSE 833.5524648 750.8247402 958.6072241 796.4109705 1035.997322 919.9577362 1215.163739 1891.315388 871.5171191 602.2865417 1.383979895 1.246623805 1.591613224 1.322312413 1.720107043 1.527441961 2.017584081 3.14022522 1.447014102 1 9.234306211 -1 0.52082625 1.202332782 69.37142816 0.886567025 0.190007051 23.18152596 0.210565299 0.038223451 1755.683071 0.1 1 68.16909538 up YAALSVDGEDENEGEDYAE ddPTM_HeLa_Curcumin_4h_R1 5 YAALSVDGEDENEGEDYAE 19 0 E7EX17;P23588-2;P23588 E7EX17 EIF4B Eukaryotic translation initiation factor 4B 0 0 ;;;; ;;;; 209.19 7.65E-13 318517900 21347.66 17177.11 16924.7 18728.27 18863.63 19932.36 15083.07 17512.78 21908.38 17844.03 FALSE FALSE TRUE 19657.97019 18661.82285 17551.94427 18650.77738 18638.69353 15798.16385 15506.26035 22852.346 19505.08553 18464.10871 1.064658494 1.010708025 0.95059797 1.010109812 1.009455361 0.855614755 0.839805516 1.237663099 1.056378395 1 14.172436 -6.954815263 6.449824269 1.0309101 0.974123263 0.049496456 0.103626642 0.445931226 45.49221205 0.016039328 0.021062649 1.11E-07 6.954815263 -0.056786837 YACGLWGLS(ph)PASR ddPTM_HeLa_Curcumin_4h_R1 2 YACGLWGLSPASR 13 0 Q15637-6;H7C0N4;H7C561 Q15637-6 SF1 Splicing factor 1 1 0 YACGLWGLS(0.987)PAS(0.013)R;YACGLWGLS(0.995)PAS(0.005)R ; 166.24 0.00018129 64524000 1397.57 1026.82 1229.21 1142.3 1387.58 2499.8 1870.86 746.08 1180.04 1472.63 TRUE FALSE FALSE 1286.95086 1115.573745 1274.765604 1137.573465 1371.034015 1981.313301 1923.351296 973.5563575 1050.592564 1523.803783 0.844564684 0.732098029 0.836568079 0.746535399 0.899744462 1.300241753 1.262204044 0.638898767 0.689453968 1 10.57346143 -5.47485928 24.57534933 0.88725426 1.088852164 0.201454046 0.194241549 408.0496016 208830.49 0.026339136 0.058894579 3.35E-06 5.47485928 0.201597904 YADEEIPR ddPTM_HeLa_Curcumin_4h_R1 2 YADEEIPR 8 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 130.22 0.0016412 16591400 6623.1 5267.8 5533.2 5836.9 6175.5 6907.2 5510.4 5096.6 5882.6 5322.4 FALSE FALSE TRUE 6098.874646 5723.125159 5738.265259 5812.748454 6101.861196 5474.56886 5665.006994 6650.529878 5237.293498 5507.353004 1.107405798 1.039178922 1.041927993 1.055452311 1.107948082 0.994047205 1.028626091 1.207572835 0.950963829 1 12.42714337 -9.533898532 1.277489955 0.999772134 1.0719645 0.285543477 0.0582433 0.609328798 1.771765842 0.038349261 0.00902894 2.92E-10 9.533898532 0.072192366 YADEEIPRS(ph)PFK ddPTM_HeLa_Curcumin_4h_R1 2 YADEEIPRSPFK 12 1 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 1 0 YADEEIPRS(1)PFK;YADEEIPRS(1)PFK ; 69.92 0.016279 37470000 5799.9 4720.3 5132.6 5445.1 5210.6 7812.8 6805 5010.3 5981.4 4506.3 TRUE FALSE FALSE 5340.831795 5128.301699 5322.818671 5422.569619 5148.466998 6192.337212 6995.929985 6537.917405 5325.255385 4662.89359 1.145390023 1.099811008 1.141526944 1.162919444 1.10413564 1.328003115 1.500340904 1.402115935 1.14204952 1 12.18700979 -1 0.253411811 1.029641055 4.095008728 0.74956203 0.073843585 14.84492012 0.185865241 0.038574013 19.72126181 0.1 1 3.065367673 YADIT(ph)VT(ph)S(ph)SKALRTLEQARQLAT(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 YADITVTSSKALRTLEQARQLATK 24 3 H3BPE1;H3BQK9;H0Y390;A0A590UJG2;Q9UPN3-4;Q9UPN3-3;Q9UPN3-2;Q9UPN3-5;Q9UPN3 H3BPE1 MACF1 "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5" 4 0 Y(0.636)ADIT(0.654)VT(0.703)S(0.706)S(0.272)KALRT(0.046)LEQARQLAT(0.983)K 45.527 0.013327 23851000 404.62 633.98 481.42 574.91 596.21 650.69 484.97 429.71 582.47 569.92 TRUE FALSE FALSE 372.5939 688.7784062 499.2618487 572.5311748 589.1005851 515.7295592 498.576953 560.7266009 518.5744983 589.7246776 0.631809918 1.167966057 0.846601588 0.970844865 0.998941722 0.874525993 0.845440206 0.950827771 0.879350175 1 9.203897756 -7.271020126 24.9995778 0.826132471 0.942376888 0.150020047 0.122052692 1173.477872 3062015.834 0.026736675 0.030784002 5.36E-08 7.271020126 0.116244417 YADS(ph)PGAS(ph)SPEQPK ddPTM_HeLa_Curcumin_4h_R1 1 YADSPGASSPEQPK 14 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 2 0 YADS(1)PGAS(0.957)S(0.043)PEQPK 177.39 0.00040623 7934300 5630.2 4723.1 4994.3 4819.5 4804.7 6254.8 5382.3 3135.5 5634.1 4194.9 TRUE FALSE FALSE 5184.563729 5131.343718 5179.393151 4799.558186 4747.407091 4957.483974 5533.312852 4091.499516 5016.053326 4340.672463 1.194414869 1.182154093 1.193223676 1.105717657 1.093703137 1.14210045 1.27475936 0.942595773 1.155593602 1 12.08370285 -9.385382883 1.101488815 0.999721211 1.149543721 0 0.095226737 0.462892584 1.001704031 0.05330538 0.013576846 4.12E-10 9.385382883 0.14982251 YADS(ph)PGASS(ph)PEQPK ddPTM_HeLa_Curcumin_4h_R1 1 YADSPGASSPEQPK 14 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 2 0 Y(0.001)ADS(0.999)PGAS(0.287)S(0.713)PEQPK 111.88 0.006412 9658800 6107.5 5364.6 5315.4 5259.9 5425.9 8078.4 5820.5 3428.6 6359 5568.8 TRUE FALSE FALSE 5624.08493 5828.29212 5512.3934 5238.135927 5361.199686 6402.848778 5983.807565 4473.964357 5661.433609 5762.315385 0.9760113 1.011449692 0.956628201 0.909033188 0.930389839 1.111159031 1.038438052 0.776417821 0.98249284 1 12.49243291 -5.728681445 0.006046969 1.935141483 3.90E-07 0.043861201 0.082016217 26882.6188 46.75472066 7310.621027 7652.723577 1.87E-06 5.728681445 -1.935141093 YADSPGAS(ph)SPEQPK ddPTM_HeLa_Curcumin_4h_R1 1 YADSPGASSPEQPK 14 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 0 YADS(0.001)PGAS(0.5)S(0.5)PEQPK 162.67 0.00024687 7760500 4293.7 3922.7 3812.6 4134.4 4070.6 4889.5 3027.9 2508.1 4679.4 4248.4 TRUE FALSE FALSE 3953.849114 4261.760709 3953.89831 4117.292948 4022.060754 3875.362584 3112.854725 3272.808144 4166.081527 4396.031584 0.899413264 0.969456344 0.899424455 0.936593123 0.914929904 0.881559313 0.708105632 0.744491499 0.947691446 1 12.10198604 -2.896724193 0.401055928 0.960908572 2.50E-13 0.787422181 0.040990612 5.080949724 0.242686327 0.011739388 2.979639164 0.001268457 2.896724193 -0.960908572 YADSPGAS(ph)SPEQPKR ddPTM_HeLa_Curcumin_4h_R1 1 YADSPGASSPEQPKR 15 1 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 0 YADSPGAS(0.665)S(0.335)PEQPKR 67.299 0.015718 17747000 1860.2 1352.3 1295.5 1666.3 1572.7 1969.4 1262.5 1101.1 1727.8 1426.5 TRUE FALSE FALSE 1712.963207 1469.186786 1343.51237 1659.405292 1553.94658 1560.92424 1297.922352 1436.820321 1538.264663 1476.070769 1.160488537 0.995336279 0.910195092 1.124204426 1.05275886 1.057486046 0.879309027 0.973408831 1.042134764 1 10.52754618 -4.775620776 24.03764259 1.060557707 0.926358961 0.279737268 0.070288063 119.7810288 203032.3925 0.011571059 0.03498412 1.68E-05 4.775620776 -0.134198746 YADSPGASS(ph)PEQPK ddPTM_HeLa_Curcumin_4h_R1 2 YADSPGASSPEQPK 14 0 A0A0U1RRL5;P32519-2;P32519 A0A0U1RRL5 ELF1 ETS-related transcription factor Elf-1 1 0 YADSPGAS(0.143)S(0.857)PEQPK;YADSPGAS(0.139)S(0.861)PEQPK ; 187.74 1.88E-05 83152000 15239.9 11850.4 14053.4 14016.4 13486.1 16423.2 11247.8 9998.8 15443.9 13315.4 TRUE FALSE FALSE 14033.64583 12874.69577 14574.23137 13958.40385 13325.28707 13016.84319 11563.383 13047.38809 13749.74281 13778.10916 1.018546571 0.934431251 1.057781674 1.01308559 0.967134671 0.944748154 0.839257612 0.946965069 0.997941202 1 13.75009029 -5.245654862 2.080766862 1.006650539 0.894017303 0.540754385 0.038985603 0.157859825 1.310813045 0.005210816 0.016262747 5.68E-06 5.245654862 -0.112633235 YAEAVTR ddPTM_HeLa_Curcumin_4h_R1 1 YAEAVTR 7 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 0 111.01 0.013235 22623000 6684 4888.4 5738.3 5480.7 6474.6 6957.3 5871.3 5845 6251 5582.7 FALSE FALSE TRUE 6154.954347 5310.931514 5950.966446 5458.022316 6397.394624 5514.277555 6036.032876 7627.113593 5565.280939 5776.698409 1.065479606 0.919371436 1.030167411 0.944834216 1.107448264 0.954572519 1.044893198 1.320324007 0.963401678 1 12.49602946 -4.267060778 4.48688109 1.018181555 1.339247682 0.730226614 0.057375986 0.071223691 3.597302296 0.007262948 0.0715258 5.41E-05 4.267060778 0.321066128 YAELLEEHR ddPTM_HeLa_Curcumin_4h_R1 3 YAELLEEHR 9 0 P40222 P40222 TXLNA Alpha-taxilin 0 0 ;; ;; 169.65 0.00074631 19631500 20361.6 17193.9 17684.6 18154.1 17880.5 23257.2 16415.9 16885.7 20456.5 18349.8 FALSE FALSE TRUE 18749.95787 18680.0641 18340.00683 18078.98314 17667.28672 18433.39456 16876.48597 22034.0722 18212.47313 18987.45418 0.987491935 0.983810885 0.965901308 0.952154142 0.930471592 0.970819699 0.888822999 1.160454265 0.959184573 1 14.21275886 -7.307992966 1.515170483 0.995336086 0.970822823 0 0.067889354 1.283027033 5.624908705 0.011897684 0.013858214 4.92E-08 7.307992966 -0.024513263 YAES(ph)S(ph)SKLEEDK ddPTM_HeLa_Curcumin_4h_R1 1 YAESSSKLEEDK 12 1 Q9P0K7-3;Q9P0K7;Q9P0K7-2;Q9P0K7-4 Q9P0K7-3 RAI14 Ankycorbin 2 0 Y(0.007)AES(0.735)S(0.787)S(0.471)KLEEDK 93.959 0.0066348 0 2090.2 1483.5 1619.3 1592.3 1773.8 2497.7 1911 963.39 1994.6 1644 TRUE FALSE FALSE 1924.758464 1611.72713 1679.312682 1585.711485 1752.648594 1979.648865 1964.617517 1257.123176 1775.79737 1701.128878 1.131459521 0.947445635 0.98717546 0.93215247 1.030285604 1.163726565 1.154890463 0.738993496 1.043893495 1 10.73227673 -7.254126526 24.8129501 1.062078107 1.005086145 0.054368805 0.117050898 1408.455365 4778972.623 0.019988139 0.024190713 5.57E-08 7.254126526 -0.056991962 YAGALRAS(ph)GEMASAQYITAALR ddPTM_HeLa_Curcumin_4h_R1 1 YAGALRASGEMASAQYITAALR 22 1 A6NJA2;P54578-2;P54578-3;P54578 A6NJA2 USP14 Ubiquitin carboxyl-terminal hydrolase;Ubiquitin carboxyl-terminal hydrolase 14 1 0 Y(0.003)AGALRAS(0.995)GEMAS(0.002)AQYITAALR 92.41 0.00012138 3089400 341.27 319.08 377.21 260.45 315.14 348.34 257.66 254.37 341.04 320.8 TRUE FALSE FALSE 314.2581194 346.6598534 391.1897344 259.3723269 311.3821613 276.0903574 264.8892461 331.926242 303.6287652 331.9477761 0.946709519 1.044320457 1.178467707 0.781364858 0.938045632 0.831728294 0.797984699 0.999935128 0.914688355 1 8.374812476 -6.225839196 24.99970755 0.994396801 0.867496373 0.388427137 0.090044721 528.2592068 370962.4914 0.01288819 0.021372235 5.95E-07 6.225839196 -0.126900427 YAHVVLR ddPTM_HeLa_Curcumin_4h_R1 2 YAHVVLR 7 0 P62269 P62269 RPS18 40S ribosomal protein S18 0 0 ; ; 86.113 0.011374 23991000 13582.5 9841 11307.5 9615.7 10555.6 15861 12893.7 13153.4 10687.6 10517.8 FALSE FALSE TRUE 12507.43079 10691.61219 11726.5659 9575.912781 10429.73136 12571.24981 13255.46252 17163.81111 9515.197019 10883.29277 1.149232228 0.98238763 1.077483272 0.879872754 0.958324984 1.155096172 1.217964343 1.577078875 0.87429395 1 13.40982749 -4.215024693 1.503034441 1.046388166 1.822360596 0.770297616 0.094544949 0.459181828 0.862647456 0.013185675 0.544406539 6.10E-05 4.215024693 0.775972431 YALTGDEVK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 YALTGDEVKK 10 1 C9JEH7;Q8TD47;P62701;P22090 C9JEH7 RPS4Y1;RPS4Y2;RPS4X "40S ribosomal protein S4, Y isoform 2;40S ribosomal protein S4, X isoform;40S ribosomal protein S4, Y isoform 1" 0 1 ; YALTGDEVK(1)K;YALTGDEVK(1)K 161.63 1.49E-09 13682500 4864.5 5417.8 4557.1 4267.4 8408.5 10227.8 7696.6 6395.7 9220.7 4059.4 FALSE TRUE FALSE 4479.469692 5886.090491 4725.990135 4249.74263 8308.234129 8106.438989 7912.545882 8345.719488 8209.212279 4200.463848 1.066422627 1.401295358 1.125111489 1.011731748 1.97793254 1.929891384 1.883731456 1.98685664 1.954358513 1 12.03633293 -5.760678256 24.99999999 1.069508925 1.939204338 0.499107769 0.301868624 3.891908271 127825.9949 0.018428655 0.035192085 1.74E-06 5.760678256 0.869695413 YALTGDEVKK ddPTM_HeLa_Curcumin_4h_R1 1 YALTGDEVKK 10 1 C9JEH7;Q8TD47;P62701;P22090 C9JEH7 RPS4Y1;RPS4Y2;RPS4X "40S ribosomal protein S4, Y isoform 2;40S ribosomal protein S4, X isoform;40S ribosomal protein S4, Y isoform 1" 0 0 74.533 0.017398 8080800 6173.4 4588.5 4615.8 5078.1 4751.3 5854 4494.5 4949 5582.7 4789.5 FALSE FALSE TRUE 5684.768876 4985.109494 4786.865608 5057.088168 4694.643851 4639.814412 4620.603574 6457.927318 4970.291777 4955.934769 1.147062894 1.005886826 0.965885515 1.020410559 0.947277168 0.936213778 0.932337448 1.303069475 1.002896933 1 12.27494148 -7.077165077 24.99407376 1.069816353 1.005148502 0.003850014 0.109203258 253.2596764 82030.50371 0.018161344 0.022243018 8.37E-08 7.077165077 -0.064667851 YALYDASFETK ddPTM_HeLa_Curcumin_4h_R1 1 YALYDASFETK 11 0 P60981;F6RFD5;P60981-2 P60981 DSTN Destrin 0 0 130.98 0.00080255 3162700 2332 1915.1 2459.5 1924.9 1770 2398.1 1940.3 1746.8 1458.2 1115.7 FALSE FALSE TRUE 2147.419739 2080.63271 2550.651234 1916.935274 1748.893906 1900.707028 1994.739596 2279.391279 1298.239108 1154.470492 1.860090625 1.802239836 2.209368928 1.660445449 1.514888356 1.646388575 1.727839395 1.974404105 1.124532084 1 10.17301558 -9.188873356 0.840050094 0.978357976 1.793996522 0.711192438 0.18681863 0.286942021 0.350374695 0.150124493 0.038406613 6.47E-10 9.188873356 0.815638546 YALYDATYETK ddPTM_HeLa_Curcumin_4h_R1 3 YALYDATYETK 11 0 P23528;G3V1A4;E9PP50;E9PK25;E9PQB7;E9PLJ3;Q9Y281;Q9Y281-3 P23528;Q9Y281 CFL1;CFL2 Cofilin-1;Cofilin-2 0 0 ;; ;; 226.9 3.53E-16 187770000 4696.75 3560.62 5037.7 4162.37 4582.6 5989.18 4702.19 4650.62 4767.9 3970.81 FALSE FALSE TRUE 4324.997282 3868.384127 5224.401594 4145.147216 4527.955488 4746.956556 4834.120796 6068.572629 4244.873299 4108.795352 1.052619299 0.941488635 1.271516624 1.008847329 1.102015335 1.155315889 1.176529951 1.476971255 1.033118697 1 12.00449976 -1 0.545930205 1.030357243 19.33210654 0.689276199 0.08376759 45.36920594 0.383585657 0.014499096 976.4940859 0.1 1 18.30174929 YAPS(ph)EAGLHEMDIR ddPTM_HeLa_Curcumin_4h_R1 1 YAPSEAGLHEMDIR 14 0 P21333-2;P21333;H0Y5F3;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 Y(0.005)APS(0.995)EAGLHEMDIR 100.58 0.0023875 6517700 2477.6 2443.5 2549 3062.5 3006.9 3903.2 3012.2 2530.1 3301.7 2490.1 TRUE FALSE FALSE 2281.495346 2654.705252 2643.468182 3049.828186 2971.044681 3093.632322 3096.714225 3301.515843 2939.51177 2576.63079 0.885456836 1.030300989 1.025939841 1.183649671 1.153073499 1.200650219 1.201846317 1.281330587 1.140835459 1 11.33127011 -6.36273418 1.278856532 0.947060955 1.21686553 0.571630859 0.074674461 0.120939465 0.390881867 0.009148275 0.016812 4.34E-07 6.36273418 0.269804575 YAPSEAGLHEMDIR ddPTM_HeLa_Curcumin_4h_R1 1 YAPSEAGLHEMDIR 14 0 P21333-2;P21333;H0Y5F3;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 77.894 0.010298 4606700 904.02 910.74 937.88 696.75 1247 2600.8 1252.3 966.27 1025.9 958.2 FALSE FALSE TRUE 832.4658631 989.4603074 972.6386578 693.8670331 1232.130339 2061.364763 1287.436168 1260.881275 913.3613367 991.4973787 0.839604704 0.99794546 0.980979556 0.699817315 1.242696517 2.07904207 1.298476623 1.271694007 0.9211939 1 9.953465148 -5.524392771 15.4270769 0.921403881 1.547323489 0.630431251 0.221810286 0.187116175 1890.078219 0.030814378 0.062678789 2.99E-06 5.524392771 0.625919608 YAPTEVGLHEMHIK ddPTM_HeLa_Curcumin_4h_R1 1 YAPTEVGLHEMHIK 14 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 94.538 0.0022843 2118500 1572.4 1394.2 1591.6 1561.9 1662 2168.4 1694.2 1692.1 1555.9 1494 FALSE FALSE TRUE 1447.942881 1514.708436 1650.586096 1555.437272 1642.181735 1718.649397 1741.734692 2208.013501 1385.221663 1545.916389 0.936624316 0.979812651 1.067707224 1.006158731 1.062270733 1.111735026 1.126668108 1.428287789 0.896052123 1 10.59424658 -1 0.551185288 0.975661743 20.48707509 0.894149812 0.04576033 24.36620333 0.202816306 0.00775548 565.5580346 0.1 1 19.51141334 YASICQQNGIVPIVEPEILPDGDHDLKR ddPTM_HeLa_Curcumin_4h_R1 2 YASICQQNGIVPIVEPEILPDGDHDLKR 28 1 P04075;H3BQN4;P04075-2;H3BPS8;P09972 P04075;P09972 ALDOA;ALDOC Fructose-bisphosphate aldolase A;Fructose-bisphosphate aldolase;Fructose-bisphosphate aldolase C 0 0 ; ; 171.75 7.50E-15 155043000 3259.7 2843.5 3216.7 2639.4 3114.8 4978.4 3475.2 2998.2 3520.1 3271.9 FALSE FALSE TRUE 3001.691305 3089.27947 3335.913732 2628.478862 3077.658044 3945.823722 3572.704759 3912.337378 3133.953837 3385.598281 0.886605869 0.912476677 0.985324736 0.776370568 0.909044071 1.165473099 1.05526541 1.155582279 0.92567209 1 11.72519508 -5.266212841 24.99098516 0.930437032 1.118422781 0.687290368 0.064726866 204.033025 1068197.721 0.010303969 0.023753929 5.42E-06 5.266212841 0.187985749 YASS(ph)PKPNNSYMFK ddPTM_HeLa_Curcumin_4h_R1 1 YASSPKPNNSYMFK 14 1 Q86VQ1;H7C0B2 Q86VQ1 GLCCI1 Glucocorticoid-induced transcript 1 protein 1 0 Y(0.001)AS(0.008)S(0.991)PKPNNS(0.001)YMFK 81.239 0.0078553 64958000 2332.6 1752 2030.1 2038.8 2173.9 2426 1552.1 923.63 2412.6 2029.8 TRUE FALSE FALSE 2147.972249 1903.435073 2105.337292 2030.363986 2147.977662 1922.820253 1595.647749 1205.240535 2147.943816 2100.335399 1.022680592 0.906252913 1.002381473 0.9666856 1.022683169 0.915482477 0.759710925 0.573832415 1.022667055 1 11.03640401 -4.504131279 1.435264565 1.000571598 0.500718057 0.935985357 0.035124116 0.127252569 0.323376647 0.005172251 0.079609145 3.13E-05 4.504131279 -0.499853542 YAYYDTER ddPTM_HeLa_Curcumin_4h_R1 1 YAYYDTER 8 0 O00303 O00303 EIF3F Eukaryotic translation initiation factor 3 subunit F 0 0 151.29 0.015318 28258000 1905.7 1331.3 1601.4 1271.7 1221.7 1600.8 1737.5 1627.1 1453.1 1569.7 FALSE FALSE TRUE 1754.861834 1446.37164 1660.749293 1266.438042 1207.132025 1268.776035 1786.249574 2123.1953 1293.698565 1624.246958 1.080415651 0.890487516 1.02247339 0.779707812 0.743194881 0.781147244 1.099740138 1.307187487 0.796491296 1 10.66555529 -7.261987704 24.67186643 1.037974056 0.934541496 0 0.17930489 88.06511493 3962475.133 0.028809839 0.03400413 5.47E-08 7.261987704 -0.10343256 YCDPDSYHR ddPTM_HeLa_Curcumin_4h_R1 2 YCDPDSYHR 9 0 P26368;P26368-2;K7ENG2 P26368 U2AF2 Splicing factor U2AF 65 kDa subunit 0 0 ; ; 150.27 0.0013411 10568200 8618.7 7558.6 8020.5 6981.9 12951.2 15194.9 9521.7 8979.2 9986.9 7442.2 FALSE FALSE TRUE 7936.520801 8211.931704 8317.746786 6953.010748 12796.7654 12043.30646 9788.853276 11716.91674 8891.362056 7700.815896 1.030607783 1.066371644 1.080112406 0.902892738 1.661741505 1.563900062 1.271144955 1.521516279 1.154600003 1 12.91079559 -5.76547554 25 1.017615705 1.492139549 0.808577733 0.110591333 27.96794856 173235.0242 0.01461105 0.027203399 1.72E-06 5.76547554 0.474523843 YDDIK(ac)K ddPTM_HeLa_Curcumin_4h_R1 2 YDDIKK 6 1 P04406;E7EUT5;P04406-2 P04406;P04406-2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 0 1 ; YDDIK(1)K;YDDIK(1)K 92.925 0.01454 36309000 12155.5 11597.4 12129.8 11154.8 13167.8 14218.6 11863.2 11579.6 10957.1 9460.9 FALSE TRUE FALSE 11193.37935 12599.82758 12579.34106 11108.64439 13010.78259 11269.50208 12196.04946 15110.16673 9755.133543 9789.665571 1.143387307 1.287053933 1.284961265 1.134731755 1.329032385 1.151163132 1.24580859 1.543481401 0.996472604 1 13.25704386 -1.000000017 0.04323874 0.322907505 2.749751761 0.610590749 0.096965327 287.0490599 0.952469363 14.11727903 49.61133571 0.099999996 1.000000017 2.426844256 YDDMAAAMK ddPTM_HeLa_Curcumin_4h_R1 1 YDDMAAAMK 9 0 P31946-2;P31946;Q4VY20;Q4VY19;A0A0J9YWE8;P61981 P31946-2;P61981 YWHAB;YWHAG "14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed;14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed" 0 0 101.64 0.007967 3959400 3298.9 2474.4 2870.1 2983.1 3274.5 3912.1 2898.9 3225.3 3298.7 2719.1 FALSE FALSE TRUE 3037.788584 2688.27611 2976.468431 2970.756723 3235.453726 3100.686362 2980.235332 4208.679123 2936.840863 2813.588523 1.079684737 0.955461713 1.057890451 1.055860407 1.149938486 1.102039739 1.059229275 1.495840308 1.0438061 1 11.45819564 -1.960980434 1.295800886 1.043024659 199.9979426 0.853324306 0.054030842 178.8785412 0.875292316 0.008482655 105165.7766 0.010940057 1.960980434 198.9549179 YDDMAACMK ddPTM_HeLa_Curcumin_4h_R1 2 YDDMAACMK 9 0 P63104;E7EX29;E7ESK7;E5RIR4;E9PD24;E7EVZ2;E5RGE1 P63104 YWHAZ 14-3-3 protein zeta/delta 0 0 ; ; 147.29 7.34E-06 8030800 8571.2 6477.8 7341.1 7079.1 7525 8833.1 7231 7303.7 7472.8 6960.4 FALSE FALSE TRUE 7892.780476 7037.712167 7613.167624 7049.80856 7435.26929 7001.01549 7433.882399 9530.564508 6653.052536 7202.273382 1.095873491 0.97715149 1.057050631 0.978831014 1.032350328 0.972056338 1.032157765 1.323271695 0.923743405 1 12.81423665 -4.261484634 10.64406361 1.031516483 1.323751923 0.760150294 0.051642699 0.023413731 120.756704 0.006372264 0.04920633 5.48E-05 4.261484634 0.29223544 YDDYRDYDS(ph)PERER ddPTM_HeLa_Curcumin_4h_R1 1 YDDYRDYDSPERER 14 2 P52756;C9JR02;C9J9P7;C9JFQ5;F8W910;P52756-3;P52756-4;P52756-2;P52756-5 P52756 RBM5 RNA-binding protein 5 1 0 YDDYRDY(0.001)DS(0.999)PERER 74.147 0.019409 44400000 3347.4 3122.7 3298.4 3553.5 2778 2950.6 2764.9 1956.4 3271.4 3011 TRUE FALSE FALSE 3082.449758 3392.612274 3420.641606 3538.796559 2744.874164 2338.6123 2842.475653 2552.897354 2912.535605 3115.632026 0.989349747 1.08890018 1.097896535 1.135819805 0.881000754 0.750606067 0.912327139 0.819383461 0.934813733 1 11.60530914 -5.581537622 7.978569779 1.019875299 0.832581155 0.674579392 0.067920574 0.118779048 14.22094835 0.009886384 0.019843307 2.62E-06 5.581537622 -0.187294143 YDDYSS(ph)SRDGYGGSR ddPTM_HeLa_Curcumin_4h_R1 1 YDDYSSSRDGYGGSR 15 1 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 1 0 YDDYS(0.248)S(0.376)S(0.376)RDGYGGSR 147.51 0.0044705 17777000 3059.1 3584.4 2954.6 3203.3 2756.4 3456.1 4120.9 3722 3637.1 3547 TRUE FALSE FALSE 2816.969007 3894.219564 3064.100075 3190.045593 2723.53173 2739.265902 4236.521363 4856.820666 3238.11923 3670.257986 0.767512534 1.061020664 0.834845966 0.869161134 0.742054575 0.746341514 1.154284353 1.323291356 0.882259297 1 11.84166576 -4.587966586 4.742756255 0.87694718 1.288481199 0.701434072 0.100290993 0.088653543 3.812845265 0.016356906 0.068576629 2.58E-05 4.587966586 0.41153402 YDDYSSSR ddPTM_HeLa_Curcumin_4h_R1 3 YDDYSSSR 8 0 P38159;P38159-2;H3BUY5;Q96E39 P38159 RBMX;RBMXL1 "RNA-binding motif protein, X chromosome;RNA-binding motif protein, X chromosome, N-terminally processed;RNA binding motif protein, X-linked-like-1" 0 0 ;; ;; 176.09 3.46E-10 125500000 9396.5 7820.4 7961.3 9264.4 8998.9 11659.9 8332.4 8549.7 11003.7 8815.2 FALSE FALSE TRUE 8652.75711 8496.360529 8256.352781 9226.066368 8891.593995 9241.505306 8566.184718 11156.46417 9796.62164 9121.527544 0.948608341 0.931462465 0.905150233 1.011460671 0.97479221 1.013153253 0.939117344 1.22309165 1.074011079 1 13.15505973 -4.257082907 24.99602372 0.97060629 1.22309175 0.706695084 0.047271121 138.6958727 795762.4386 0.005026499 0.052812619 5.53E-05 4.257082907 0.25248546 YDEFHDYLER ddPTM_HeLa_Curcumin_4h_R1 4 YDEFHDYLER 10 0 Q96K76-2;Q96K76-4;Q96K76 Q96K76-2 USP47 Ubiquitin carboxyl-terminal hydrolase 47 0 0 ;;; ;;; 161.67 0.00048308 33987400 20213.6 16787.1 18588.8 18323.8 19458 24208.9 18377.6 17846.4 19388.9 17328.4 FALSE FALSE TRUE 18613.67223 18238.10212 19277.71728 18247.98097 19225.97606 19187.70125 18893.226 23287.68521 17261.98618 17930.56061 1.038097616 1.017151807 1.075131877 1.017702757 1.072246232 1.070111619 1.053688527 1.298770614 0.962713133 1 14.13013298 -1.351454122 1.082865568 1.026021182 200 0.845363322 0.033987007 265.0010087 0.552498018 0.004379992 130658.8734 0.044519049 1.351454122 198.9739788 MPFLSISS(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 MPFLSISSPK 10 0 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 MPFLSIS(0.072)S(0.928)PK 149.33 0.00084357 200690000 4210.4 2683.4 3821 3890.7 3577.6 4907.3 4554.5 4082.7 2680.8 2236.9 TRUE FALSE FALSE 3877.142397 2915.341139 3962.609621 3874.601314 3534.939457 3889.470663 4682.287012 5327.496436 2386.722947 2314.632108 1.675057726 1.259526785 1.711982482 1.673959892 1.527214387 1.680383958 2.022907656 2.301660128 1.031145701 1 11.17656719 -1 0.058478849 2.82E-15 5.067059892 0.779538232 0.182137197 134.932476 0.596620617 10.91788893 59.02061806 0.1 1 5.067059892 up GLNNDS(ph)PERR ddPTM_HeLa_Curcumin_4h_R1 3 GLNNDSPERR 10 1 G5EA48;Q7Z6B7-2;Q7Z6B7 G5EA48 SRGAP1 SLIT-ROBO Rho GTPase-activating protein 1 1 0 GLNNDS(1)PERR;GLNNDS(1)PERR;GLNNDS(1)PERR ;; 96.23 0.0070674 86855100 10873.5 9733 9311.1 10509.9 8621.5 9980.5 7851.2 4003.6 11788.1 10216.4 TRUE FALSE FALSE 10012.851 10574.27715 9656.177557 10466.41282 8518.694243 7910.431797 8071.483542 5224.27921 10494.97492 10571.41914 0.947162426 1.000270353 0.913423016 0.990066961 0.805823147 0.748284756 0.763519395 0.494189015 0.992768784 1 13.36788144 -3.827278123 0.513060796 0.981583663 1.77E-16 0.903624768 0.048344108 1.191210433 0.154312544 0.009274538 0.773767042 0.000148841 3.827278123 -0.981583663 down YDGES(ph)DKEQFDDDQK ddPTM_HeLa_Curcumin_4h_R1 2 YDGESDKEQFDDDQK 15 1 Q08AD1-2;Q08AD1-3;Q08AD1 Q08AD1-2 CAMSAP2 Calmodulin-regulated spectrin-associated protein 2 1 0 Y(0.055)DGES(0.945)DKEQFDDDQK;Y(0.009)DGES(0.991)DKEQFDDDQK ; 83.894 0.0055322 54582000 6539.6 7127.4 7290.2 6759.5 9400.2 7253.3 6373.2 3391.7 5461 5581.6 TRUE FALSE FALSE 6021.983759 7743.460697 7560.381225 6731.53098 9288.108754 5748.883818 6552.014839 4425.813717 4861.941963 5775.560185 1.04266661 1.340728942 1.309029944 1.165520013 1.608174525 0.995381164 1.134437982 0.766300337 0.841813055 1 12.49574517 -7.428137718 8.38088523 1.018722583 1.198874448 0.174299726 0.215694145 0.477580092 38.53378604 0.03501075 0.039927675 3.73E-08 7.428137718 0.180151865 YDGIILPGK ddPTM_HeLa_Curcumin_4h_R1 2 YDGIILPGK 9 0 P62913;Q5VVC8;P62913-2 P62913 RPL11 60S ribosomal protein L11 0 0 ; ; 111.95 0.0029861 16134600 12179.1 8424.3 10001.8 10004 10843 15717.8 10370.6 9739.5 11471 9610.4 FALSE FALSE TRUE 11215.11138 9152.458954 10372.47551 9962.606099 10713.70431 12457.7511 10661.57112 12709.02871 10212.66 9944.360685 1.127786063 0.920366753 1.043051015 1.00183475 1.077364815 1.252745299 1.072122328 1.278013652 1.026980047 1 13.27966291 -5.421261378 5.685981411 1.044777752 1.187100239 0.538432472 0.072402376 0.170873043 7.882237043 0.01095411 0.024744174 3.79E-06 5.421261378 0.142322487 YDGT(ph)VAEVEDYGFAWQAGLR ddPTM_HeLa_Curcumin_4h_R1 1 YDGTVAEVEDYGFAWQAGLR 20 0 O60292 O60292 SIPA1L3 Signal-induced proliferation-associated 1-like protein 3 1 0 Y(0.032)DGT(0.968)VAEVEDYGFAWQAGLR 70.134 0.018706 7114800 0 0 114.87 0 69.439 0 0 0 153.94 0 TRUE FALSE FALSE 0 0 119.1271832 0 68.61098528 0 0 0 137.0531671 0 0 YDLDFKSPDDPSR ddPTM_HeLa_Curcumin_4h_R1 1 YDLDFKSPDDPSR 13 1 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 0 96.334 0.0076937 27788000 6324.5 4796.7 5728.3 5218.5 5233.1 9071.7 6763.2 8075.3 6844 5833 FALSE FALSE TRUE 5823.909151 5211.305374 5940.595837 5196.90723 5170.6987 7190.127161 6952.95719 10537.4218 6093.230323 6035.696316 0.964910898 0.863414112 0.984243661 0.861028613 0.856686359 1.191267218 1.151972668 1.745850229 1.00953229 1 12.5593045 -3.721677458 1.102295857 0.960564225 3.328296306 0.891956959 0.082927122 1.057107927 0.450468602 0.012231022 3.887762968 0.000189812 3.721677458 2.367732081 YDS(ph)DGDKSDDLVVDVSNEDPATPR ddPTM_HeLa_Curcumin_4h_R1 2 YDSDGDKSDDLVVDVSNEDPATPR 24 1 H0YKH0;H0YLW9;H0YLI3;H0YNT2;H0YKT5;H0YKN8;H0YL70;Q04726-2;Q04726-7;Q04726-3;Q04726-6;Q04726-5;Q04726-4;Q04726;A0A0D9SES8 H0YKH0 TLE3 Transducin-like enhancer protein 3 1 0 Y(0.15)DS(0.812)DGDKS(0.037)DDLVVDVSNEDPATPR;Y(0.147)DS(0.786)DGDKS(0.067)DDLVVDVSNEDPATPR ; 122.3 3.72E-07 104832000 4798.3 4419.7 4371.3 5198.7 4689.8 4360.5 2816.8 3166.3 4290.1 3922.7 TRUE FALSE FALSE 4418.509492 4801.719174 4533.304223 5177.189157 4633.877198 3456.083147 2895.831827 4131.690294 3819.486763 4059.013533 1.088567322 1.182976882 1.116848758 1.275479649 1.141626447 0.851458887 0.713432415 1.017905031 0.940988921 1 11.98691343 -5.251265933 23.58187156 1.083082928 0.846182079 0.492784506 0.112171936 216.7980094 502530.3168 0.015931823 0.04004002 5.61E-06 5.251265933 -0.236900849 YDS(ph)PINSASHIPSSK ddPTM_HeLa_Curcumin_4h_R1 1 YDSPINSASHIPSSK 15 0 F8W8M4;O14639-3;O14639-2;O14639;A0A0A0MRL6;A0A3B3IS55;O14639-5;O14639-6;J3QSX6;O14639-4 F8W8M4 ABLIM1 Actin-binding LIM protein 1 1 0 YDS(0.998)PINS(0.002)ASHIPSSK 132.25 0.00068052 5982300 4312.3 2968.4 2550.7 2967 4174.7 9553.4 6130.3 2143.2 4688.7 2927.7 TRUE FALSE FALSE 3970.976905 3224.975269 2645.231186 2954.72334 4124.919429 7571.917151 6302.299719 2796.651814 4174.361341 3029.437357 1.310796837 1.06454595 0.873175733 0.975337329 1.361612386 2.499446682 2.080353206 0.923158819 1.377932879 1 11.56483416 -5.509362611 22.91258308 1.112163747 1.870857519 0.410960644 0.392163085 142.2281845 241104.1725 0.053790334 0.11547461 3.09E-06 5.509362611 0.758693772 YEALAKLDKARYQEEMMNYVGK ddPTM_HeLa_Curcumin_4h_R1 1 YEALAKLDKARYQEEMMNYVGK 22 3 Q8WW32 Q8WW32 HMGB4 High mobility group protein B4 0 0 29.384 0.020092 24062000 10291 8915.5 9810.2 9983.9 11500 12197 7933.2 4111.9 11110 8503.1 FALSE FALSE TRUE 9476.456491 9686.116093 10173.77464 9942.589267 11362.87001 9667.204711 8155.784241 5365.599381 9891.260796 8798.582092 1.077043595 1.10087239 1.156297064 1.130021765 1.291443313 1.098723023 0.926943018 0.609825461 1.124188044 1 13.10305533 -4.345228721 2.535556439 1.078046733 0.554258904 0.783669249 0.080367507 0.177025172 1.608649259 0.013453303 0.181664145 4.52E-05 4.345228721 -0.523787829 SVLNNLK(ac)GDK ddPTM_HeLa_Curcumin_4h_R1 1 SVLNNLKGDK 10 1 E9PER7;P29083 E9PER7 GTF2E1 General transcription factor IIE subunit 1 0 1 SVLNNLK(1)GDK 125.23 0.0021135 2185800 902.34 810.49 723.65 771.83 1026.1 1264.7 1064.5 1111.5 929.16 650.2 FALSE TRUE FALSE 830.9188369 880.5451441 750.4691056 768.636372 1013.864428 1002.386964 1094.367005 1450.391233 827.2334726 672.7944016 1.235026384 1.308787859 1.115450877 1.142453579 1.506945399 1.489886006 1.626599452 2.155771852 1.229548686 1 9.394021891 -1 0.37478251 1.093144218 15.17465875 0.881497046 0.109421013 13.28646545 0.16232953 0.030367967 136.9251612 0.1 1 14.08151453 up GSVSQPSTPS(ph)PPKPTGIFQTSANSSFEPVK ddPTM_HeLa_Curcumin_4h_R1 1 GSVSQPSTPSPPKPTGIFQTSANSSFEPVK 30 1 O15027;O15027-5;F1T0I1;O15027-2;O15027-3;O15027-4;A0A3F2YNZ0;A0A3F2YNX0 O15027;O15027-4 SEC16A Protein transport protein Sec16A 1 0 GS(0.011)VS(0.094)QPS(0.111)T(0.032)PS(0.381)PPKPT(0.295)GIFQT(0.031)S(0.031)ANS(0.011)S(0.004)FEPVK 49.888 0.0062778 17110000 1578 1254.9 1101.4 1192.4 1286.1 1462.4 1020.7 503.35 1397.7 1298.8 TRUE FALSE FALSE 1453.099635 1363.367964 1142.218853 1187.466165 1270.764097 1159.081755 1049.338095 656.8190979 1244.375807 1343.933203 1.081229061 1.014461106 0.849907458 0.883575286 0.945555995 0.862454884 0.780796317 0.488728976 0.925920874 1 10.39224572 -3.824296958 0.510599734 1.029969388 3.84E-16 0.778604038 0.07341332 1.840010234 0.235841145 0.014977973 1.248852126 0.000149866 3.824296958 -1.029969388 down YEAWLAEAESR ddPTM_HeLa_Curcumin_4h_R1 1 YEAWLAEAESR 11 0 M0R0F9;W4VSQ9;Q15642-4;Q15642-2;Q15642-3;Q15642 M0R0F9 TRIP10 Cdc42-interacting protein 4 0 0 156.16 0.003591 4305600 2072.1 1559 1577.8 1748.8 1869.5 1797.7 1689.3 1681.3 1843.7 1638.6 FALSE FALSE TRUE 1908.091099 1693.753013 1636.274656 1741.563929 1847.207434 1424.836756 1736.697211 2193.92063 1641.450723 1695.541228 1.125358126 0.998945343 0.965045632 1.027143369 1.089450025 0.840343326 1.024273066 1.29393529 0.968098384 1 10.72753015 -11.6667226 12.76699087 0.45675798 1.045610254 0 0.113857122 0 0 0 0.014424637 2.15E-12 11.6667226 0.588852275 YEDDGIS(ph)DDEIEGK ddPTM_HeLa_Curcumin_4h_R1 2 YEDDGISDDEIEGK 14 0 I3VM54;Q9Y2K7-3;Q9Y2K7 I3VM54 KDM2A Lysine-specific demethylase 2A 1 0 YEDDGIS(1)DDEIEGK;YEDDGIS(1)DDEIEGK ; 168.93 0.00020647 14900400 4025 3827.4 3929.8 4100.3 4619.8 4374.5 4016 3105.8 4020.5 4101 TRUE FALSE FALSE 3706.417003 4158.223401 4075.441845 4083.334045 4564.711902 3467.179389 4128.678151 4052.744123 3579.461209 4243.509445 0.873432014 0.979902002 0.960394197 0.962254025 1.075692646 0.817054712 0.972939546 0.955045388 0.843514373 1 12.05104217 -5.238136323 24.99793018 0.953058767 0.920805895 0.062823587 0.071481773 2419.856747 2595854.492 0.009859847 0.02512352 5.78E-06 5.238136323 -0.032252873 YEDKPEPEVDALGS(ph)PPALLK ddPTM_HeLa_Curcumin_4h_R1 2 YEDKPEPEVDALGSPPALLK 20 1 Q68DQ2 Q68DQ2 CRYBG3 Very large A-kinase anchor protein 1 0 YEDKPEPEVDALGS(1)PPALLK;YEDKPEPEVDALGS(1)PPALLK ; 93.269 0.00041454 20601700 5001.9 3465.7 4955.6 4641.4 5550.7 5683.9 4912.9 4456.3 4586.2 4196.8 TRUE FALSE FALSE 4605.994337 3765.259665 5139.258895 4622.195117 5484.511528 4504.995069 5050.742752 5815.005356 4083.105334 4342.638488 1.060644203 0.867044235 1.183441567 1.064374833 1.262944531 1.037386622 1.163058534 1.339048915 0.940236067 1 12.08435614 -6.71132631 24.99993013 1.017317934 1.167206093 0.490252352 0.098541835 83.99480742 41902.23731 0.014303893 0.020228743 1.94E-07 6.71132631 0.149888159 YEDSDKPFVDS(ph)PASR ddPTM_HeLa_Curcumin_4h_R1 1 YEDSDKPFVDSPASR 15 1 E9PQ01;E9PKN0;O94913 E9PQ01;O94913 PCF11 Pre-mRNA cleavage complex 2 protein Pcf11 1 0 Y(0.001)EDS(0.02)DKPFVDS(0.927)PAS(0.052)R 62.438 0.018354 13789000 3052.5 2677.9 2835.7 3129.1 3255.2 5414 5627.2 3181.9 3622.2 2387 TRUE FALSE FALSE 2810.891404 2909.365744 2940.793537 3116.152613 3216.383866 4291.075372 5785.084087 4152.046662 3224.853722 2469.948072 1.13803664 1.177905631 1.190629702 1.261626772 1.30220708 1.737314003 2.342188547 1.681025892 1.305636243 1 11.270265 -5.279678097 1.861431139 1.096732081 2.028102057 0.769617831 0.182014384 0.095689413 0.63169769 0.024201193 0.077700691 5.25E-06 5.279678097 0.931369976 YEEVSVSGFEEFHR ddPTM_HeLa_Curcumin_4h_R1 1 YEEVSVSGFEEFHR 14 0 I3L0K2;I3L3M7;Q9BRA2;I3L2R6 I3L0K2 TXNDC17 Thioredoxin domain-containing protein 17 0 0 201.08 5.26E-09 8856900 2772.8 2373.5 2620.2 2439.6 2415.2 3820.5 3067.9 2440.8 2939 2663.5 FALSE FALSE TRUE 2553.329954 2578.654764 2717.306917 2429.505582 2386.400317 3028.085234 3153.977017 3184.988684 2616.599053 2756.056427 0.926443279 0.935632064 0.985940234 0.881515182 0.865874985 1.098702191 1.144380422 1.155632611 0.949399667 1 11.42838971 -5.096448262 5.247668016 0.951869018 1.144004581 0.82732343 0.041310648 0.079659792 3.380701761 0.006925135 0.018340085 8.01E-06 5.096448262 0.192135564 YEILTPNSIPK ddPTM_HeLa_Curcumin_4h_R1 2 YEILTPNSIPK 11 0 P35579;P35579-2 P35579 MYH9 Myosin-9 0 0 ; ; 198.25 1.29E-16 4326600 3378.1 3275.5 3216.7 3380.4 3492 3601.7 3041.1 3123.6 3525.7 2919.7 FALSE FALSE TRUE 3110.71982 3558.619625 3335.913732 3366.4128 3450.360181 2854.66682 3126.425081 4075.971261 3138.939531 3021.159358 1.029644402 1.177898682 1.104183307 1.114278461 1.14206494 0.944891177 1.034842824 1.349141432 1.038985091 1 11.56088657 -1.000000003 0.091235885 0.916372886 1.591296201 0.164901609 0.098718499 171.8458357 1.134151309 1.107225778 14.58363034 0.099999999 1.000000003 0.674923316 YELGRPAANTK ddPTM_HeLa_Curcumin_4h_R1 1 YELGRPAANTK 11 1 P62241;Q5JR95 P62241 RPS8 40S ribosomal protein S8 0 0 96.756 0.0066039 3892400 1238.7 1109.7 834.16 974.12 1225.9 1244.2 987.05 1021.7 1076.2 1057.2 FALSE FALSE TRUE 1140.655588 1205.617523 865.0747034 970.0893495 1211.281943 986.138895 1014.743966 1333.211627 958.1435525 1093.937621 1.042706244 1.102089827 0.790789791 0.886786715 1.107267836 0.901458068 0.927606791 1.218727285 0.875866717 1 10.09531476 -12.47039301 12.88935053 0.567915246 1.004514117 0 0.126518343 0 0 0 0.014869189 3.39E-13 12.47039301 0.436598871 YELY(ph)MRRLRST(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 YELYMRRLRSTK 12 3 O75445-2;O75445;O75445-3 O75445-2 USH2A Usherin 2 0 Y(0.074)ELY(0.926)MRRLRS(0.183)T(0.817)K 79.201 0.011668 20712000 2122.1 2002.2 2214.6 2352.2 2184.1 2776.5 1971.6 1735.7 2544.5 2201.9 TRUE FALSE FALSE 1954.133546 2175.261246 2296.675024 2342.46722 2158.056034 2200.622602 2026.91779 2264.90694 2265.374716 2278.415861 0.857672025 0.954725291 1.008013973 1.028112233 0.947173899 0.965856427 0.889617135 0.994070915 0.994276223 1 11.15381538 -7.00684172 24.84581952 0.931390047 0.970501364 0 0.051464629 623.5137753 2264310.761 0.010312411 0.013272164 9.84E-08 7.00684172 0.039111317 YEPQS(ph)PGYEPR ddPTM_HeLa_Curcumin_4h_R1 2 YEPQSPGYEPR 11 0 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 0 YEPQS(1)PGYEPR;YEPQS(1)PGYEPR ; 196.37 1.71E-05 327020000 3537.2 2994 3148.9 3212.9 3082.4 3600.6 3262 2450.5 3306 2888 TRUE FALSE FALSE 3257.226888 3252.788019 3265.601004 3199.605871 3045.644393 2853.794973 3353.522941 3197.646169 2943.340071 2988.357785 1.089972193 1.088486805 1.09277444 1.070690359 1.01916993 0.954970983 1.122195929 1.070034581 0.984935635 1 11.54513717 -9.447017057 1.203358226 1.000310408 1.065042244 0.282084302 0.04456196 0.590886993 1.541887748 0.031214898 0.007924896 3.57E-10 9.447017057 0.064731837 YEQGFITDPVVLS(ph)PKDR ddPTM_HeLa_Curcumin_4h_R1 1 YEQGFITDPVVLSPKDR 17 1 P12268;H0Y4R1;E7ETK5 P12268 IMPDH2 Inosine-5-monophosphate dehydrogenase 2 1 0 YEQGFIT(0.001)DPVVLS(0.999)PKDR 63.522 0.012501 4898300 1478.2 1147.4 1289 1422.4 1106.2 2368.7 1636.9 1819.5 1846.9 1679.3 TRUE FALSE FALSE 1361.19891 1246.576143 1336.771474 1416.514486 1093.009287 1877.404919 1682.827009 2374.257174 1644.299691 1737.65555 0.783353703 0.717389671 0.769296006 0.815187156 0.629013781 1.080424092 0.96844683 1.366356626 0.946274819 1 10.76292641 -4.003082084 1.254401297 0.854582706 1.85671296 0.625641473 0.124034398 1.462364155 1.270900444 0.020708648 2.198494009 9.93E-05 4.003082084 1.002130254 YESGPDGGEEDGTGS(ph)LKR ddPTM_HeLa_Curcumin_4h_R1 4 YESGPDGGEEDGTGSLKR 18 1 Q07866-6;G3V5R9;G3V3H3 Q07866-6 KLC1 Kinesin light chain 1 1 0 YESGPDGGEEDGT(0.095)GS(0.905)LKR;YESGPDGGEEDGT(0.255)GS(0.745)LKR;YESGPDGGEEDGT(0.066)GS(0.934)LKR;YESGPDGGEEDGT(0.461)GS(0.539)LKR ;;; 124.82 0.00012011 66035800 7105.5 6002.6 6025.2 6599.5 6697.7 7380.9 5797.34 5377.49 6538.4 5671.7 TRUE FALSE FALSE 6543.092177 6521.437997 6248.499212 6572.193018 6617.834302 5850.01814 5959.997758 7017.061946 5821.153878 5868.791153 1.114896068 1.11120635 1.064699535 1.119854642 1.12763159 0.996801213 1.015540953 1.195657123 0.991882949 1 12.51884765 -9.360529598 1.048265926 0.999239681 1.090881072 0.334871728 0.054415689 0.557243633 1.081430025 0.038136159 0.009585648 4.36E-10 9.360529598 0.091641391 YESLTDPSK ddPTM_HeLa_Curcumin_4h_R1 2 YESLTDPSK 9 0 P08238;Q58FF7;Q58FF8;Q58FF6;P07900;P07900-2;G3V2J8 P08238;P07900 HSP90AB1;HSP90AB3P;HSP90AB2P;HSP90AB4P;HSP90AA1 Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Putative heat shock protein HSP 90-beta 2;Putative heat shock protein HSP 90-beta 4;Heat shock protein HSP 90-alpha 0 0 ; ; 133.13 0.0004416 28654000 19583.6 18172.1 18910.1 18237.8 22919 22465 19524.7 18284.7 17319 15581 FALSE FALSE TRUE 18033.5374 19742.81535 19610.92494 18162.33682 22645.70589 17805.50577 20072.51053 23859.62086 15419.14903 16122.43859 1.118536585 1.224555159 1.216374609 1.126525415 1.40460798 1.104392842 1.24500462 1.479901488 0.956378214 1 13.97678235 -1 0.083066217 0.786752845 2.331289418 0.613242354 0.096765103 84.27771013 0.51276612 1.412595123 14.97368805 0.1 1 1.544536572 YESLTDPSK(ac)LDSGK ddPTM_HeLa_Curcumin_4h_R1 1 YESLTDPSKLDSGK 14 1 P08238;Q58FF7;Q58FF8;P07900;P07900-2;G3V2J8 P08238;P07900 HSP90AB1;HSP90AB3P;HSP90AB2P;HSP90AA1 Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Putative heat shock protein HSP 90-beta 2;Heat shock protein HSP 90-alpha 0 1 YESLTDPSK(1)LDSGK 258.65 3.69E-62 2462000 1411.7 1883.8 1480.7 1212.9 2708.1 4093.8 3370.4 2865.5 3873.6 1604.5 FALSE TRUE FALSE 1299.962455 2046.627278 1535.576045 1207.881341 2675.807676 3244.699733 3464.964353 3739.177759 3448.675771 1660.256256 0.782989042 1.232717703 0.924903032 0.727527053 1.611683538 1.954336701 2.087005751 2.252169053 2.077194867 1 10.69719022 -5.504397311 2.405559304 0.914031909 2.113610596 0.505054854 0.398790747 0.057287757 0.656902609 0.023959925 0.058512219 3.13E-06 5.504397311 1.199578688 YESLTDPSKLDSGK ddPTM_HeLa_Curcumin_4h_R1 4 YESLTDPSKLDSGK 14 1 P08238;Q58FF7;Q58FF8;P07900;P07900-2;G3V2J8 P08238;P07900 HSP90AB1;HSP90AB3P;HSP90AB2P;HSP90AA1 Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta-3;Putative heat shock protein HSP 90-beta 2;Heat shock protein HSP 90-alpha 0 0 ;;; ;;; 106.29 0.0012077 185500000 35704.8 29527.5 31829.7 33272.3 33885.6 39009.1 32988.1 32593 36755.1 30728.3 FALSE FALSE TRUE 32878.7274 32079.72553 33009.33668 33134.62804 33481.53635 30918.17294 33913.6573 42530.45566 32723.15749 31796.10614 1.034048863 1.008919941 1.038156576 1.042097038 1.053007441 0.972388657 1.066597814 1.3375995 1.029156128 1 14.95656248 -4.272957485 3.529602082 1.019526102 1.371665165 0.945136065 0.022640386 0.042922837 0.940688269 0.003200745 0.039390498 5.33E-05 4.272957485 0.352139063 YESQEPLAGQES(ph)PLPLATR ddPTM_HeLa_Curcumin_4h_R1 4 YESQEPLAGQESPLPLATR 19 0 Q9C0C2;Q9C0C2-2 Q9C0C2 TNKS1BP1 182 kDa tankyrase-1-binding protein 1 0 YESQEPLAGQES(0.939)PLPLAT(0.061)R;YESQEPLAGQES(1)PLPLATR;YESQEPLAGQES(1)PLPLATR;YESQEPLAGQES(0.99)PLPLAT(0.01)R ;;; 246.1 1.07E-33 432287000 16300.6 13610 13741.5 14015.8 15243.5 16787.7 13727.5 16168.7 16381.6 13576.4 TRUE FALSE FALSE 15010.39031 14786.38776 14250.77208 13957.80633 15061.73122 13305.74178 14112.6567 21098.4622 14584.57946 14048.17889 1.068493676 1.052548367 1.014421313 0.993566956 1.072148307 0.947150651 1.004589763 1.501864574 1.038182926 1 13.7780955 -4.259866884 24.99057304 1.02609996 1.501864731 0.939668644 0.03651695 24.79498373 394011.8024 0.005500133 0.046744628 5.50E-05 4.259866884 0.475764771 YESQNTELKTQS(ph)PEFEAQSSK ddPTM_HeLa_Curcumin_4h_R1 1 YESQNTELKTQSPEFEAQSSK 21 1 Q9H5H4;H3BS42 Q9H5H4 ZNF768 Zinc finger protein 768 1 0 YESQNT(0.001)ELKT(0.031)QS(0.964)PEFEAQS(0.003)S(0.001)K 91.503 0.00018846 13275000 3391.5 2868 2745.3 3100.9 2763.9 3721.1 2324.2 2200.3 3465.6 2773.3 TRUE FALSE FALSE 3123.059196 3115.89714 2847.043233 3088.069297 2730.942298 2949.301915 2389.410797 2871.161341 3085.432351 2869.671969 1.088298325 1.08580255 0.992114522 1.076105329 0.95165661 1.027748797 0.832642484 1.000519004 1.075186427 1 11.48667012 -5.336147433 1.37216732 1.044307269 0.925535373 0.386774745 0.058647849 0.352983058 1.234428117 0.008825201 0.032909877 4.61E-06 5.336147433 -0.118771896 YESQQNGT(ph)PLK ddPTM_HeLa_Curcumin_4h_R1 2 YESQQNGTPLK 11 0 Q5JSZ5;A0A494C0D3;H0Y412;A0A494C065 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 YESQQNGT(1)PLK;YESQQNGT(1)PLK ; 168.76 0.0007208 33105300 5185.3 4418.9 5146 5352.5 4866.7 7096.5 6154.6 1886.5 5818.5 4218.5 TRUE FALSE FALSE 4774.878033 4800.850026 5336.715287 5330.352773 4808.667781 5624.605906 6327.281512 2461.685166 5180.225107 4365.092561 1.093877843 1.099827772 1.222589261 1.221131671 1.101618743 1.288542185 1.449518292 0.563947988 1.186738892 1 12.09179653 -7.928801524 0.812527598 1.016501182 1.159897663 0 0.223442012 1.093569531 1.569384477 0.062998104 0.049041184 1.18E-08 7.928801524 0.143396481 YESSS(ph)YTDQFSR ddPTM_HeLa_Curcumin_4h_R1 2 YESSSYTDQFSR 12 0 A0A087X0K9;G5E9E7;Q07157-2;G3V1L9;Q07157 A0A087X0K9;G3V1L9 TJP1 Tight junction protein ZO-1 1 0 YESS(0.019)S(0.981)YTDQFSR;YESS(0.003)S(0.996)YTDQFSR ; 272.59 7.49E-52 12379000 4296.6 3901.6 4020.3 4073.2 4443.3 6514 4079.8 5633.1 5404.8 4099.1 TRUE FALSE FALSE 3956.519576 4238.836919 4169.295855 4056.346178 4390.31655 5162.922972 4194.268208 7350.606258 4811.906962 4241.54342 0.932801856 0.999361907 0.98296668 0.956337299 1.035075234 1.217227424 0.988854243 1.733002714 1.134470754 1 12.05037362 -1.864751083 1.138585024 0.979752676 200 0.814890741 0.097597053 99.17671042 0.608959315 0.011869572 50992.11527 0.013653655 1.864751083 199.0202473 YETPSDAIEVIS(ph)PAS(ph)SPAPPQEK ddPTM_HeLa_Curcumin_4h_R1 2 YETPSDAIEVISPASSPAPPQEK 23 0 A0A088AWL3;O75376-2;O75376;E7EVK1 A0A088AWL3 NCOR1 Nuclear receptor corepressor 1 2 0 YETPSDAIEVIS(0.992)PAS(0.612)S(0.396)PAPPQEK;YETPSDAIEVIS(1)PAS(0.628)S(0.372)PAPPQEK ; 125.05 2.31E-05 7205300 6164 5257.4 5811.1 5782.6 5854.7 5921.9 5057 2136.12 5673.3 4300.2 TRUE FALSE FALSE 5676.112896 5711.826229 6026.464478 5758.673133 5784.886526 4693.631186 5198.88581 2787.413155 5050.953184 4449.63163 1.275636585 1.283662717 1.354373795 1.294190983 1.300082121 1.0548359 1.168385665 0.626436835 1.135139626 1 12.11947019 -4.259732646 6.01465649 1.177412511 0.611269444 0.695858451 0.113687661 0.078555888 13.57182386 0.020402155 0.179745869 5.50E-05 4.259732646 -0.566143067 YETPSDAIEVIS(ph)PASS(ph)PAPPQEK ddPTM_HeLa_Curcumin_4h_R1 3 YETPSDAIEVISPASSPAPPQEK 23 0 A0A088AWL3;O75376-2;O75376;E7EVK1 A0A088AWL3 NCOR1 Nuclear receptor corepressor 1 2 0 YETPSDAIEVIS(0.997)PAS(0.2)S(0.803)PAPPQEK;YETPSDAIEVIS(0.998)PAS(0.075)S(0.926)PAPPQEK;YETPSDAIEVIS(0.998)PAS(0.043)S(0.959)PAPPQEK ;; 108.05 3.97E-05 26653900 8145.7 7052.9 7403.3 7230.9 7974.5 7884.3 6908.2 2332.04 7219.7 6357.1 TRUE FALSE FALSE 7500.95925 7662.521249 7677.672811 7200.980452 7879.409296 6249.007306 7102.0255 3043.068261 6427.716973 6578.008752 1.140308493 1.164869421 1.167172787 1.09470521 1.197841109 0.949984645 1.079661911 0.462612376 0.97715239 1 12.68343521 -4.260892339 7.303707082 1.084636809 0.454864287 0.840903274 0.081313626 0.030798573 14.20690943 0.011577077 0.094350413 5.48E-05 4.260892339 -0.629772521 YEWDVAEAR ddPTM_HeLa_Curcumin_4h_R1 1 YEWDVAEAR 9 0 P13639 P13639 EEF2 Elongation factor 2 0 0 141.52 0.019446 37481000 5264.2 4356.8 4949.5 5021.1 5288.7 5034.4 4725.1 4472.4 4516 4126.4 FALSE FALSE TRUE 4847.533015 4733.382378 5132.932824 5000.324019 5225.635707 3990.208691 4857.673589 5836.014172 4020.606098 4269.792093 1.135308912 1.10857444 1.202150529 1.171093091 1.223861863 0.934520605 1.137683869 1.3668146 0.941639783 1 12.05995011 -13.52287874 0.167992871 0.359389488 1.196608671 0.364994378 0.101522195 60.34200831 0.66457327 12.58219771 0.168140372 3.00E-14 13.52287874 0.837219182 YEYDPDIS(ph)PPR ddPTM_HeLa_Curcumin_4h_R1 2 YEYDPDISPPR 11 0 Q9BRD0;H7C462 Q9BRD0 BUD13 BUD13 homolog 1 0 YEYDPDIS(1)PPR;YEYDPDIS(1)PPR ; 103.14 0.0092454 87584000 1887.59 1606.33 1626.67 1372.69 1956.65 1835.1 1582.73 1475.2 1583.55 1481.77 TRUE FALSE FALSE 1738.18526 1745.174008 1686.955821 1367.010172 1933.318227 1454.479574 1627.137144 1924.981689 1409.838527 1533.261397 1.133652268 1.13821036 1.100240197 0.891570201 1.260918869 0.94861814 1.061226186 1.255481741 0.919503047 1 10.58238796 -9.45359008 1.197066758 1.000177418 1.096328314 0.172829288 0.113106393 0.893643022 2.297419051 0.07024183 0.017565303 3.52E-10 9.45359008 0.096150896 YEYQPFAGK ddPTM_HeLa_Curcumin_4h_R1 2 YEYQPFAGK 9 0 D6RD66;O75083 D6RD66 WDR1 WD repeat-containing protein 1 0 0 ; ; 152.34 5.81E-07 10334500 6733.5 5343.8 5570 5590.2 5497.3 7037.2 5067.2 5083.8 6314.1 5896.5 FALSE FALSE TRUE 6200.53637 5805.69426 5776.4291 5567.069234 5431.748288 5577.605394 5209.371994 6633.827217 5621.459027 6101.402936 1.016247646 0.951534315 0.94673785 0.912424453 0.890245792 0.914151295 0.853799044 1.0872626 0.921338762 1 12.57492529 -7.042586698 2.278533854 1.007830604 0.92594752 0.026818075 0.063995301 0.265331809 2.717071584 0.009259804 0.011893745 9.07E-08 7.042586698 -0.081883084 YFDDEFTAQSIT(ph)ITPPDR ddPTM_HeLa_Curcumin_4h_R1 1 YFDDEFTAQSITITPPDR 18 0 P31751;P31751-2;M0R0P9;M0R283 P31751 AKT2 RAC-beta serine/threonine-protein kinase 1 0 YFDDEFTAQS(0.042)IT(0.827)IT(0.131)PPDR 120.59 0.0010237 4389100 1386.6 1128.7 1329.6 1369.3 1599.9 1420.1 947.21 1186.1 1020.5 1259.5 TRUE FALSE FALSE 1276.849147 1226.259799 1378.876146 1363.634199 1580.822237 1125.555252 973.7861633 1547.73643 908.5537032 1303.267531 0.979729116 0.9409118 1.058014654 1.046319475 1.212968327 0.863640983 0.747188233 1.187581516 0.697135225 1 10.34791755 YFDDEFTAQSITIT(ph)PPDR ddPTM_HeLa_Curcumin_4h_R1 1 YFDDEFTAQSITITPPDR 18 0 P31751;P31751-2;M0R0P9;M0R283 P31751 AKT2 RAC-beta serine/threonine-protein kinase 1 0 YFDDEFTAQSITIT(1)PPDR 228.32 2.11E-56 0 500.81 508.44 604.28 471.02 520.57 422.33 312.19 351.04 456.44 333.79 TRUE FALSE FALSE 461.17036 552.387288 626.6751484 469.071044 514.3625427 334.7339974 320.9492112 458.07048 406.369674 345.3891777 1.335219485 1.599318461 1.814402966 1.358094215 1.489225998 0.96915022 0.929239339 1.32624445 1.176555898 1 8.432079068 -2.867480879 14.10317612 1.244537639 1.154279289 0 0.278918274 0 0 0.041700918 0 0.00135681 2.867480879 -0.09025835 YFDEHYEYR ddPTM_HeLa_Curcumin_4h_R1 2 YFDEHYEYR 9 0 P33552 P33552 CKS2 Cyclin-dependent kinases regulatory subunit 2 0 0 ; ; 173.39 0.00097006 67747000 16835.9 15153.1 17095.5 15694.5 17863.2 20363.8 14600.4 9437.7 14934.4 13800.7 FALSE FALSE TRUE 15503.32075 16462.86644 17729.07427 15629.56032 17650.19301 16140.11833 15010.04793 12315.21128 13296.13368 14280.2733 1.085645942 1.152839732 1.241508051 1.094486078 1.235984259 1.130238756 1.051103688 0.862393249 0.931083979 1 13.80173597 -3.060939849 10.85920184 1.07427264 1.095542885 0 0.116365955 0 0 0.015066636 0 0.000869081 3.060939849 0.021270245 DLQS(ph)PDFTTGFHSDK ddPTM_HeLa_Curcumin_4h_R1 1 DLQSPDFTTGFHSDK 15 0 E9PDR5;E7EPI0;Q9P2D0;Q9P2D0-2 E9PDR5 IBTK Inhibitor of Bruton tyrosine kinase 1 0 DLQS(0.847)PDFT(0.109)T(0.044)GFHSDK 119.47 0.0013629 4723900 4749.9 3595.7 4542.4 4085.1 4183.4 4581.4 3438.7 1761.2 4980.2 4487.5 TRUE FALSE FALSE 4373.940403 3906.496286 4710.74534 4068.196939 4133.515687 3631.165997 3535.180667 2298.181772 4433.88452 4643.440291 0.94196116 0.841293533 1.014494652 0.876116992 0.890183878 0.781999072 0.761327905 0.494930833 0.954870579 1 12.18097837 -3.800248568 0.563169772 0.967725183 3.06E-15 0.863974531 0.053398166 1.358946352 0.203189726 0.009749227 0.964281183 0.000158399 3.800248568 -0.967725183 down YFDNKDDDSDTET(ph)SNDLPK ddPTM_HeLa_Curcumin_4h_R1 1 YFDNKDDDSDTETSNDLPK 19 1 C9J3R1;C9IZP0;J3KR59;J3KR68;Q9UID6 C9J3R1 ZNF639 Zinc finger protein 639 1 0 YFDNKDDDS(0.172)DT(0.257)ET(0.42)S(0.15)NDLPK 69.069 0.008925 23414000 3194.6 2683.4 3127 2843 3126.5 3270.6 2054.9 1309 3587.5 2993.4 TRUE FALSE FALSE 2941.744039 2915.341139 3242.889371 2831.236419 3089.218529 2592.240693 2112.554964 1708.108074 3193.960225 3097.420427 0.949739988 0.94121583 1.046964546 0.914062681 0.997352023 0.836903079 0.68203688 0.551461487 1.031167806 1 11.5968515 -4.728911304 1.509979997 0.976328829 0.529857327 0.930001508 0.040590834 0.08504066 0.30635651 0.005256021 0.043577099 1.87E-05 4.728911304 -0.446471502 YFDPANGK ddPTM_HeLa_Curcumin_4h_R1 1 YFDPANGK 8 0 P13639 P13639 EEF2 Elongation factor 2 0 0 98.523 0.014768 12956000 10231 8241.8 9303.9 9408.4 9179.2 10591 7301.9 8085.3 10398 9404.4 FALSE FALSE TRUE 9421.205554 8954.184467 9648.710719 9369.470534 9069.744035 8394.307215 7506.771662 10550.47075 9257.365415 9731.2022 0.968144055 0.920151928 0.991522992 0.962827649 0.932027087 0.862617695 0.771412566 1.08418986 0.951307477 1 13.24840233 -5.64222108 2.837365747 0.978779178 0.893201814 0.090015435 0.075810979 0.30045414 4.865899781 0.010305827 0.022397587 2.28E-06 5.64222108 -0.085577364 YFDPANGK(ac)FSK ddPTM_HeLa_Curcumin_4h_R1 1 YFDPANGKFSK 11 1 P13639 P13639 EEF2 Elongation factor 2 0 1 YFDPANGK(1)FSK 155.97 2.08E-07 3041600 2774.1 2079.3 2119.1 2209.6 2455.6 2544.9 2297.1 2111 2236.7 2305.6 FALSE TRUE FALSE 2554.527058 2259.025427 2197.63571 2200.457261 2426.318574 2017.059053 2361.550444 2754.634182 1991.339606 2385.719428 1.070757536 0.946894844 0.921162683 0.922345367 1.017017569 0.845472032 0.98986931 1.154634593 0.834691449 1 11.22020867 -7.251264473 24.7432995 1.033413281 0.964925236 0 0.099824465 901.4188237 2192065.737 0.01298887 0.015801142 5.61E-08 7.251264473 -0.068488046 YFDRVDENNPEYLR ddPTM_HeLa_Curcumin_4h_R1 1 YFDRVDENNPEYLR 14 1 E7EV99;E7ENY0;P35611-5;P35611-2;P35611-6;P35611-4;P35611;P35611-3;A0A0A0MSR2;D6RJE2;D6RAH3;D6RF25 E7EV99 ADD1 Alpha-adducin 0 0 164.13 1.82E-10 0 1493.1 1096.9 1344 1326.9 1436.5 1702.4 1091.1 1003.4 1304.1 1520.4 FALSE FALSE TRUE 1374.919559 1191.711148 1393.809822 1321.409639 1419.370676 1349.30305 1121.713329 1309.332041 1161.043493 1573.233787 0.873944846 0.757491454 0.885952129 0.839932151 0.902199462 0.857662136 0.7129985 0.832255226 0.737998066 1 10.61951736 -13.52287875 0.141482479 1.636827649 0.767194601 0 0.100446856 36.50880966 0.358289016 6.404220764 0.155971008 3.00E-14 13.52287875 -0.869633048 YFDS(ph)GDYNMAK ddPTM_HeLa_Curcumin_4h_R1 2 YFDSGDYNMAK 11 0 O43768;O43768-3;A6NMQ3;Q5T5H1;O43768-2;O43768-9;O43768-4;O43768-5;O43768-7;H3BQ52;H3BMD8;O43768-6;H3BTD3;P56211-2;P56211 O43768;H3BTD3;P56211 ENSA;ARPP19 Alpha-endosulfine;cAMP-regulated phosphoprotein 19 1 0 YFDS(1)GDYNMAK;Y(0.008)FDS(0.992)GDYNMAK ; 122.39 0.0038877 45209000 3088.55 2311.77 3036.1 3436.4 2765.63 5100.2 4554.2 1632.11 3870.6 2811.9 TRUE FALSE FALSE 2844.088008 2511.589098 3148.620537 3422.181087 2732.651669 4042.361029 4681.978595 2129.732826 3446.004864 2909.613316 0.97747972 0.863203741 1.082143981 1.176163537 0.939180356 1.389312115 1.609141177 0.731964215 1.184351489 1 11.50661172 -5.267728688 24.95613684 0.99804271 1.280039373 0.13724333 0.227204521 460.3661644 1826747.596 0.028465114 0.065162906 5.40E-06 5.267728688 0.281996663 YFEADPPGQVAAS(ph)PDPTT ddPTM_HeLa_Curcumin_4h_R1 5 YFEADPPGQVAASPDPTT 18 0 H0Y8X4;O43598 H0Y8X4 DNPH1 2-deoxynucleoside 5-phosphate N-hydrolase 1 1 0 YFEADPPGQVAAS(0.993)PDPT(0.003)T(0.003);YFEADPPGQVAAS(1)PDPTT;YFEADPPGQVAAS(0.998)PDPT(0.001)T(0.001);YFEADPPGQVAAS(1)PDPTT;YFEADPPGQVAAS(0.976)PDPT(0.012)T(0.012) ;;;; 166.9 1.51E-05 93308000 28236.8 21904.6 24733.3 24338.5 25217.4 35415.4 25252.6 30292 27550.8 22281.7 TRUE FALSE FALSE 26001.82748 23797.93602 25649.93786 24237.79374 24916.69898 28069.84683 25961.11999 39527.89135 24528.54617 23055.98742 1.127768983 1.0321803 1.112506586 1.051258109 1.08070405 1.217464528 1.12600339 1.714430644 1.063868822 1 14.49285383 -1.748506288 1.105589222 1.066237325 200 0.911121455 0.05841217 105.4835144 0.535433428 0.00954383 52724.15387 0.017844062 1.748506288 198.9337627 YFEGEFTGLPPALT(ph)PPAPHSLLTAR ddPTM_HeLa_Curcumin_4h_R1 2 YFEGEFTGLPPALTPPAPHSLLTAR 25 0 Q6P5Z2 Q6P5Z2 PKN3 Serine/threonine-protein kinase N3 1 0 YFEGEFTGLPPALT(0.982)PPAPHS(0.009)LLT(0.009)AR;YFEGEFTGLPPALT(1)PPAPHSLLTAR ; 104.67 3.57E-07 74370000 2619.3 2040.79 2745.35 1908.02 2197.37 4387.7 2460.66 1382.81 2967.07 2784.49 TRUE FALSE FALSE 2411.979641 2217.186794 2847.095086 1900.125119 2171.167798 3477.64156 2529.699497 1804.422403 2641.589844 2881.25082 0.837129355 0.769522312 0.988145519 0.659479246 0.753550431 1.20699022 0.87798656 0.626263563 0.916820509 1 11.49247954 -9.155892527 0.849219469 1.002708077 0.847132167 0.070370001 0.159811199 1.148374166 1.458115104 0.11375903 0.030679958 6.98E-10 9.155892527 -0.155575911 YFEQLLEEEREK ddPTM_HeLa_Curcumin_4h_R1 2 YFEQLLEEEREK 12 1 O15460-2;O15460 O15460-2 P4HA2 Prolyl 4-hydroxylase subunit alpha-2 0 0 ; ; 160.38 0.00018308 13089100 3930.3 2776.7 4170.5 4200.4 3631.9 4516.8 2661.9 1858.51 4508 3883.4 FALSE FALSE TRUE 3619.212608 3016.705575 4325.062399 4183.019858 3588.591965 3579.964765 2736.58575 2425.161143 4013.483678 4018.347861 0.900671802 0.750732809 1.076328518 1.040980025 0.893051595 0.890904643 0.68102261 0.603521952 0.998789507 1 11.97238675 -4.729169454 1.940489054 0.949564745 0.592977473 0.670978984 0.086288634 0.17812688 1.197116877 0.012820827 0.081543001 1.87E-05 4.729169454 -0.356587272 YFGTDAVPDGS(ph)DEEEVAYTG ddPTM_HeLa_Curcumin_4h_R1 1 YFGTDAVPDGSDEEEVAYTG 20 0 Q9NWZ5;Q9NWZ5-4 Q9NWZ5;Q9NWZ5-4 UCKL1 Uridine-cytidine kinase-like 1 1 0 YFGTDAVPDGS(1)DEEEVAYTG 90.259 0.0011568 28999000 8098.8 6700.2 7070.5 7339.3 7499.3 9137.7 6823.6 6151 7880.9 7236.8 TRUE FALSE FALSE 7457.771434 7279.335432 7332.53895 7308.931921 7409.875745 7242.438017 7015.051851 8026.411584 7016.384987 7488.278261 0.995926056 0.972097347 0.979202254 0.976049723 0.989529968 0.967169991 0.936804377 1.071863425 0.936982407 1 12.87041833 -7.402600715 6.409059005 0.998219744 0.981827289 0 0.037810983 0.567206573 27.64128538 0.005070654 0.005770998 3.96E-08 7.402600715 -0.016392455 YFLHDDRDDGVDYWAK ddPTM_HeLa_Curcumin_4h_R1 2 YFLHDDRDDGVDYWAK 16 1 Q9NYF8-2;Q9NYF8;Q9NYF8-4;H0YF14 Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 0 0 ; ; 88.78 0.0050325 196576000 7619.7 6180.13 6519.38 6596.51 7120.6 8692.2 6824.4 6480.1 8029 6847.8 FALSE FALSE TRUE 7016.592705 6714.312899 6760.993958 6569.215389 7035.691496 6889.339739 7015.874297 8455.852659 7148.238788 7085.76054 0.990238474 0.947578296 0.954166306 0.927100959 0.99293385 0.972279503 0.990137087 1.193358513 1.008817437 1 12.790707 -4.261663299 5.588723427 0.982592697 1.200622478 0.868758512 0.025251343 0.041196069 5.134920931 0.003843869 0.034146676 5.47E-05 4.261663299 0.218029781 YFQFQEEGKEGENR ddPTM_HeLa_Curcumin_4h_R1 2 YFQFQEEGKEGENR 14 1 O15144 O15144 ARPC2 Actin-related protein 2/3 complex subunit 2 0 0 ; ; 198.52 1.24E-06 36304000 4043.4 2814.7 3092.2 3501.6 3075.9 3920.8 3431.8 3275 4251.6 3498 FALSE FALSE TRUE 3723.360623 3057.990126 3206.799652 3487.111307 3039.221901 3107.581883 3528.087072 4273.532424 3785.210117 3619.55524 1.028679044 0.844852454 0.885965109 0.963408783 0.839667224 0.858553518 0.974729446 1.180678879 1.045766639 1 11.82159672 -7.302372228 24.95042963 1.01354289 0.929457279 0.152341001 0.094818036 700.8664707 427208.3406 0.016104947 0.018416791 4.98E-08 7.302372228 -0.084085612 YFQINQDEEEEEDED ddPTM_HeLa_Curcumin_4h_R1 11 YFQINQDEEEEEDED 15 0 K7ERI7;P35268 K7ERI7 RPL22 60S ribosomal protein L22 0 0 ;;;;;;;;;; ;;;;;;;;;; 220.82 1.23E-13 1609068200 95888.29 82333.6 80520.35 89400.26 84497.89 103467.87 83713.21 76250.36 97220.27 84703.79 FALSE FALSE TRUE 88298.63067 89450.14951 83504.505 89030.34541 83490.30785 82007.46744 86061.97737 99498.74375 86555.44961 87647.2404 1.007431954 1.020570061 0.952733989 1.01578036 0.952572009 0.93565373 0.981913144 1.135218215 0.987543352 1 16.41942105 YFQISQDEDES(ph)ESED ddPTM_HeLa_Curcumin_4h_R1 1 YFQISQDEDESESED 15 0 C9JYQ9;H0Y8C2;Q6P5R6 C9JYQ9 RPL22L1 60S ribosomal protein L22-like 1 1 0 YFQISQDEDES(0.904)ES(0.096)ED 83.499 0.012976 3800700 2103.8 1708.8 1857.8 1780.3 1767.4 1945.4 1363.3 1043.1 2156.7 1800.1 TRUE FALSE FALSE 1937.28201 1856.501058 1926.651702 1772.93359 1746.324909 1541.902111 1401.550529 1361.136388 1920.115406 1862.653341 1.040065785 0.996697033 1.034358707 0.951832287 0.937546923 0.827798752 0.752448401 0.73075132 1.030849575 1 10.86314348 -5.193873362 1.027830522 1.018781151 0.709155248 0.974178107 0.01794628 0.076544642 0.131840965 0.003141659 0.018024772 6.40E-06 5.193873362 -0.309625903 YFQS(ph)PSR ddPTM_HeLa_Curcumin_4h_R1 1 YFQSPSR 7 0 Q16629-4;Q16629;H7BZZ6 Q16629-4 SRSF7 Serine/arginine-rich splicing factor 7 1 0 YFQS(0.972)PS(0.028)R 99.013 0.020322 48284000 3005.6 1827.8 2292 1994.8 2341.3 3012.5 2353.9 5672.8 2506 2199.7 TRUE FALSE FALSE 2767.703589 1985.786887 2376.943536 1986.546046 2313.381527 2387.673542 2419.944099 7402.410606 2231.09807 2276.139411 1.215964002 0.872436406 1.044287325 0.872769935 1.016361966 1.04900145 1.063179209 3.252178038 0.980211519 1 11.15237321 -4.261440001 10.08659784 1.058102604 3.257238725 0.97713278 0.102566693 0.008666176 30.02918437 0.016629661 0.128889189 5.48E-05 4.261440001 2.199136121 YFS(ph)LDLTHDEVPEFVV ddPTM_HeLa_Curcumin_4h_R1 1 YFSLDLTHDEVPEFVV 16 0 Q96NE9-3;Q96NE9-2;Q96NE9 Q96NE9-3 FRMD6 FERM domain-containing protein 6 1 0 YFS(0.982)LDLT(0.018)HDEVPEFVV 83.243 0.010399 888600 188.85 188.56 149.13 166.36 128.96 192.67 185.5 0 147 200.44 TRUE FALSE FALSE 173.9023232 204.8582862 154.656889 165.6716464 127.4222362 152.7080702 190.7046308 0 130.8744678 207.4052751 0.83846625 0.987719749 0.74567481 0.798782222 0.614363527 0.736278622 0.919478208 0 0.631008386 1 7.696308777 -4.236048108 0.577032792 0.916777038 4.21E-132 0.411219567 0.209858096 2.364375058 0.519521331 0.034019616 1.453013288 5.81E-05 4.236048108 -0.916777038 YGDFRADDADEFGYSR ddPTM_HeLa_Curcumin_4h_R1 1 YGDFRADDADEFGYSR 16 1 Q7KZF4 Q7KZF4 SND1 Staphylococcal nuclease domain-containing protein 1 0 0 100.68 0.0023556 11546000 2279.7 1278.3 1034.3 1376.3 687.98 2119.8 1123.5 1040 3422.5 2298.3 FALSE FALSE TRUE 2099.259339 1388.790556 1072.632068 1370.605235 679.7762878 1680.129585 1155.022386 1357.091212 3047.060313 2378.165754 0.882722046 0.583975509 0.45103335 0.576328724 0.285840584 0.70648128 0.485677831 0.570646184 1.281264902 1 11.21563356 -7.28027344 2.363141607 0.953400021 0.510733495 0.729236145 0.145617501 0.089101813 0.946053386 0.017756275 0.020895208 5.24E-08 7.28027344 -0.442666525 YGEHEAS(ph)PDNGQNEFSDIIK ddPTM_HeLa_Curcumin_4h_R1 2 YGEHEASPDNGQNEFSDIIK 20 0 P46939;Q5SYY2 P46939 UTRN Utrophin 1 0 YGEHEAS(1)PDNGQNEFSDIIK;Y(0.002)GEHEAS(0.998)PDNGQNEFSDIIK ; 116.94 6.38E-05 18377400 7746.5 7258.8 7908.1 8101.3 7822.4 9679.7 7010.1 4796.7 8869.1 7943.4 TRUE FALSE FALSE 7133.356351 7886.218327 8201.181143 8067.778967 7729.122989 7672.021107 7206.784539 6259.191749 7896.181919 8219.432559 0.867864819 0.95946019 0.99777948 0.981549384 0.940347516 0.933400335 0.876798305 0.761511419 0.96067239 1 13.00482308 -4.283393244 1.644895886 0.946079241 0.69945467 0.727129955 0.036609068 0.573421316 1.515288553 0.007642433 0.220959449 5.21E-05 4.283393244 -0.246624571 YGEPGEVFINK ddPTM_HeLa_Curcumin_4h_R1 2 YGEPGEVFINK 11 0 P23246;P23246-2 P23246 SFPQ "Splicing factor, proline- and glutamine-rich" 0 0 ; ; 175.93 1.29E-09 10628900 3722.9 2912.33 2826.53 3080.93 3017.46 4255.6 3614.32 3857.7 3434.25 3173.14 FALSE FALSE TRUE 3428.228537 3164.058828 2931.283688 3068.181928 2981.47876 3372.94059 3715.728092 5033.894971 3057.521367 3283.406379 1.04410729 0.963651301 0.892756896 0.934450864 0.908044395 1.027268696 1.131668658 1.533131873 0.931204065 1 11.6809776 -4.231263481 1.994298337 0.993634557 1.719332418 0.909448598 0.053926128 0.202049106 0.795853759 0.008787411 0.273843956 5.87E-05 4.231263481 0.725697861 YGGDEIPFS(ph)PYR ddPTM_HeLa_Curcumin_4h_R1 3 YGGDEIPFSPYR 12 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 YGGDEIPFS(1)PYR;YGGDEIPFS(1)PYR;YGGDEIPFS(1)PYR ;; 201.09 8.47E-09 127235600 9890.6 8867.5 8959.4 8831.4 9958 11930.8 9581 9357.7 9171.5 8125.85 TRUE FALSE FALSE 9107.748573 9633.967187 9291.443245 8794.858007 9839.257354 9456.217592 9849.817074 12210.81965 8165.409396 8408.222683 1.083195453 1.145779263 1.10504248 1.045983002 1.170194668 1.12463929 1.171450549 1.452247415 0.971121925 1 13.03758516 -1 0.553984187 1.050765498 18.07072555 0.803608146 0.055946787 38.81932447 0.320418085 0.010391583 790.7432665 0.1 1 17.01996005 YGGDEIPFS(ph)PYRVR ddPTM_HeLa_Curcumin_4h_R1 2 YGGDEIPFSPYRVR 14 1 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 1 0 YGGDEIPFS(0.992)PY(0.008)RVR;YGGDEIPFS(0.863)PY(0.137)RVR ; 67.902 0.015814 9112100 4737.2 4016.8 3448.8 4227.1 3239.6 6071.7 3857.4 3569.9 6290.7 5179.2 TRUE FALSE FALSE 4362.245621 4363.994293 3576.615562 4209.60938 3200.969886 4812.360978 3965.628262 4658.346076 5600.625949 5359.176814 0.813976805 0.8143031 0.667381519 0.78549552 0.597287605 0.89796645 0.739969663 0.869227913 1.0450534 1 12.3877957 -8.624561954 0.631073107 1.000784903 0.761233176 0.567973087 0.086206094 0.439935945 0.347226947 0.052163682 0.019659732 2.37E-09 8.624561954 -0.239551728 YGGGGYGR ddPTM_HeLa_Curcumin_4h_R1 1 YGGGGYGR 8 0 J3KP15;Q01130 J3KP15 SRSF2 Serine/arginine-rich splicing factor 2 0 0 101.33 0.0075719 0 805.82 545.45 800.06 678.95 696.76 863.49 684.99 635.96 661.65 653.98 FALSE FALSE TRUE 742.0384967 592.5962675 829.7109274 676.1406848 688.4515921 684.3924405 704.2089758 829.8612764 589.0686504 676.7057563 1.096545271 0.875707443 1.226102955 0.999164967 1.017357375 1.011358976 1.040642804 1.226325133 0.870494517 1 9.40238485 -1 0.007522945 4.60E-11 2.223511577 0.114887758 0.108393537 51779.52218 30.43389288 4026.610966 5020.594721 0.1 1 2.223511577 YGGPNHIVGS(ph)PFK ddPTM_HeLa_Curcumin_4h_R1 1 YGGPNHIVGSPFK 13 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;A0A0A0MT44 O75369-8 FLNB Filamin-B 1 0 YGGPNHIVGS(1)PFK 98.582 0.0077689 23423000 3123.7 1977.6 2202.5 2572.2 2431 3214.1 2429 2190.9 2145 2300.1 TRUE FALSE FALSE 2876.455849 2148.534932 2284.126588 2561.556918 2402.011913 2547.45943 2497.151203 2858.895324 1909.698867 2380.028304 1.208580522 0.902735034 0.95970564 1.07627162 1.009236701 1.070348376 1.049210717 1.201202238 0.802384939 1 11.21676302 -4.256685937 23.19695481 1.066254516 1.201202394 0.025448531 0.116629078 288.8348043 1409376.395 0.014126528 0.148256544 5.54E-05 4.256685937 0.134947879 YGGPYHIGGSPFK ddPTM_HeLa_Curcumin_4h_R1 1 YGGPYHIGGSPFK 13 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 70.54 0.018475 6391000 4692.1 3320.5 3537.6 2968.3 4692.7 6663.8 4422.5 3788.2 4131.7 3410.3 FALSE FALSE TRUE 4320.715334 3607.509224 3668.706568 2956.017961 4636.742617 5281.652763 4546.583447 4943.204741 3678.462847 3528.807671 1.224412248 1.022302591 1.039644806 0.8376818 1.31396864 1.496724462 1.288419169 1.40081444 1.042409559 1 11.78496509 -5.544069392 23.64382732 1.079038031 1.388082228 0.710124452 0.106603872 65.24399137 72796.82695 0.017941836 0.035887324 2.86E-06 5.544069392 0.309044197 YGGSVGSQPPPVAPEPGPVPS(ph)SPSQEPPTKR ddPTM_HeLa_Curcumin_4h_R1 1 YGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR 31 1 E9PS08;A0A087WTZ5;E9PJ81;E9PRQ7;Q04323;Q04323-2 E9PS08 UBXN1 UBX domain-containing protein 1 1 0 YGGSVGSQPPPVAPEPGPVPS(0.459)S(0.459)PS(0.065)QEPPT(0.017)KR 75.765 1.65E-05 26879000 3171 3496.6 3272.6 3984.5 3313.7 3978.9 4125 4701.8 3586.2 3721.9 TRUE FALSE FALSE 2920.012004 3798.830523 3393.885435 3968.013195 3274.186292 3153.631289 4240.736398 6135.357176 3192.802832 3851.235748 0.758201314 0.986392621 0.881245828 1.030322072 0.850165117 0.818862177 1.101136538 1.593087927 0.829033339 1 11.91110572 -4.32294671 2.615580328 0.894902122 1.686455891 0.861809434 0.084594301 0.126307042 1.212645756 0.014358225 0.20412498 4.75E-05 4.32294671 0.791553769 YGGSVGSQPPPVAPEPGPVPSS(ph)PSQEPPTKR ddPTM_HeLa_Curcumin_4h_R1 3 YGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR 31 1 E9PS08;A0A087WTZ5;E9PJ81;E9PRQ7;Q04323;Q04323-2 E9PS08 UBXN1 UBX domain-containing protein 1 1 0 YGGSVGSQPPPVAPEPGPVPS(0.389)S(0.568)PS(0.037)QEPPT(0.007)KR;YGGSVGS(0.001)QPPPVAPEPGPVPS(0.245)S(0.684)PS(0.062)QEPPT(0.007)KR;YGGSVGSQPPPVAPEPGPVPS(0.37)S(0.576)PS(0.053)QEPPT(0.001)KR ;; 112.54 1.82E-11 140376000 10510.9 11697.8 8600.7 12828.4 10571.8 11240.1 11551.9 13809.1 10142.2 8762.2 TRUE FALSE FALSE 9678.951174 12708.90571 8919.449508 12775.31948 10445.73819 8908.776558 11876.01522 18019.43102 9029.626035 9066.685798 1.067529127 1.401714584 0.983760738 1.409039617 1.152101046 0.982583576 1.309851856 1.987433051 0.995912535 1 13.14635957 -4.295569042 2.747755268 1.088611903 2.121598882 0.726663067 0.157160256 0.149414089 1.587613288 0.02210779 0.334572545 5.06E-05 4.295569042 1.032986978 YGLLQSSDNS(ph)EDEEEPPDNADSK ddPTM_HeLa_Curcumin_4h_R1 1 YGLLQSSDNSEDEEEPPDNADSK 23 0 A0A0A0MR87;E9PSF2;Q15468;Q15468-2 A0A0A0MR87 STIL SCL-interrupting locus protein 1 0 YGLLQS(0.041)S(0.034)DNS(0.922)EDEEEPPDNADS(0.002)K 58.904 0.0055292 0 637.4 718.56 768.44 791.01 724.83 798.77 402.94 382.8 727.52 519.86 TRUE FALSE FALSE 586.9491174 780.6691246 796.9190624 787.7370102 716.1868757 633.096098 414.2454119 499.5139578 647.7128762 537.9250963 1.091135404 1.451259906 1.481468457 1.464399069 1.331387735 1.176922405 0.7700801 0.92859389 1.204094921 1 9.071261488 -3.129639488 13.2981376 1.127004504 1.105958444 0 0.240625669 0 0 0.035725769 0 0.000741926 3.129639488 -0.02104606 YGLQDS(ph)DEEEEEHPSK ddPTM_HeLa_Curcumin_4h_R1 6 YGLQDSDEEEEEHPSK 16 0 A0A3B3ITD8;P52948-6;P52948-2;P52948-5;P52948;P52948-4;P52948-3 A0A3B3ITD8 NUP98 Nuclear pore complex protein Nup98-Nup96;Nuclear pore complex protein Nup98;Nuclear pore complex protein Nup96 1 0 YGLQDS(1)DEEEEEHPSK;YGLQDS(1)DEEEEEHPSK;Y(0.001)GLQDS(0.999)DEEEEEHPSK;YGLQDS(0.598)DEEEEEHPS(0.402)K;YGLQDS(1)DEEEEEHPSK;Y(0.001)GLQDS(0.999)DEEEEEHPSK ;;;;; 194.67 2.43E-07 111078200 16980.3 14902.2 14005.8 14049.09 21784.5 24263.6 14891.6 10584.16 18685.1 15908 TRUE FALSE FALSE 15636.29134 16190.27977 14524.86727 13990.95859 21524.73407 19231.05585 15309.41822 13811.22166 16635.39128 16460.80182 0.949910673 0.983565682 0.882391237 0.84995608 1.307635819 1.168293991 0.930053006 0.839036993 1.010606377 1 14.00674699 YGMGTS(ph)VER ddPTM_HeLa_Curcumin_4h_R1 1 YGMGTSVER 9 0 P08559-3;P08559;P08559-2;P08559-4 P08559-3 PDHA1 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial" 1 0 YGMGT(0.005)S(0.995)VER 99.013 0.013709 12864000 6487 3233.3 4165.4 5382.4 5583.3 4629.4 2824.4 954.18 4772.4 3868 TRUE FALSE FALSE 5973.547105 3512.772045 4319.773388 5360.129055 5516.722794 3669.210256 2903.645063 1245.105089 4248.87966 4002.412712 1.492486541 0.877663624 1.079292342 1.339224473 1.378349309 0.916749601 0.725473676 0.311088631 1.061579594 1 11.96665422 -4.604267248 1.573012698 1.213900137 0.259590527 0.673941631 0.187602188 0.290802567 1.048581665 0.032908148 0.348390096 2.49E-05 4.604267248 -0.95430961 YGPADVEDT(ph)TGSGATDSKDDDDIDLFGSDDEEESEEAKR ddPTM_HeLa_Curcumin_4h_R1 1 YGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKR 39 2 P24534;C9JZW3 P24534 EEF1B2 Elongation factor 1-beta 1 0 YGPADVEDT(0.22)T(0.22)GS(0.195)GAT(0.174)DS(0.164)KDDDDIDLFGS(0.027)DDEEES(0.001)EEAKR 59.694 9.36E-05 41172000 2496.2 2164 2312.1 2249.4 2885.3 2886.5 2627.5 2682.7 3086.2 2661.9 TRUE FALSE FALSE 2298.623136 2351.046517 2397.78846 2240.092579 2850.894682 2287.807362 2701.220578 3500.64288 2747.651581 2754.400827 0.834527464 0.853560054 0.870529967 0.813277631 1.035032612 0.830600739 0.980692625 1.270927182 0.99754965 1 11.4275228 -4.29038716 3.261893503 0.90703033 1.310410353 0.675026451 0.076015353 0.142696625 2.465685341 0.011345219 0.138938293 5.12E-05 4.29038716 0.403380023 YGPADVEDTTGS(ph)GATDSKDDDDIDLFGSDDEEESEEAKR ddPTM_HeLa_Curcumin_4h_R1 1 YGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKR 39 2 P24534;C9JZW3 P24534 EEF1B2 Elongation factor 1-beta 1 0 YGPADVEDT(0.146)T(0.146)GS(0.34)GAT(0.1)DS(0.262)KDDDDIDLFGS(0.007)DDEEESEEAKR 60.516 5.49E-05 16579000000 1630.9 1775.7 1562.5 1329.5 1411.4 1674.6 1176.6 1527.7 1865.1 1492.5 TRUE FALSE FALSE 1501.812544 1929.183596 1620.407625 1323.998881 1394.569977 1327.269083 1209.612229 1993.488697 1660.503196 1544.364264 0.972447096 1.249176532 1.049239265 0.85730997 0.903005858 0.859427477 0.783242825 1.290815091 1.075201774 1 10.59279736 -6.274474318 24.39732995 1.014737992 0.923726654 0.105525439 0.150092608 1126.146857 2107792.132 0.02215401 0.033975607 5.32E-07 6.274474318 -0.091011338 YGPADVEDTTGSGAT(ph)DSKDDDDIDLFGSDDEEESEEAKR ddPTM_HeLa_Curcumin_4h_R1 1 YGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKR 39 2 P24534;C9JZW3 P24534 EEF1B2 Elongation factor 1-beta 1 0 YGPADVEDT(0.017)T(0.022)GS(0.06)GAT(0.618)DS(0.186)KDDDDIDLFGS(0.09)DDEEES(0.007)EEAKR 66.1 1.46E-06 156120000 4044.7 3710.1 3047.1 4062 3699.4 5253.4 3763.8 3864.9 4339.1 3466.2 TRUE FALSE FALSE 3724.557727 4030.784512 3160.028207 4045.19252 3655.287071 4163.785622 3869.402098 5043.290218 3863.111586 3586.650192 1.038450233 1.12382984 0.881052803 1.127846961 1.019136764 1.160912104 1.078834537 1.406128267 1.077080668 1 11.80842133 -1.000000071 0.778795807 1.023457168 79.82306216 0.651128309 0.076387368 164.0615985 0.588632495 0.010616238 22777.1656 0.099999984 1.000000071 78.79960499 YGPADVEDTTGSGATDS(ph)KDDDDIDLFGSDDEEESEEAKR ddPTM_HeLa_Curcumin_4h_R1 4 YGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKR 39 2 P24534;C9JZW3 P24534 EEF1B2 Elongation factor 1-beta 1 0 YGPADVEDT(0.162)T(0.162)GS(0.131)GAT(0.131)DS(0.41)KDDDDIDLFGS(0.004)DDEEESEEAKR;YGPADVEDT(0.08)T(0.08)GS(0.193)GAT(0.154)DS(0.42)KDDDDIDLFGS(0.072)DDEEES(0.001)EEAKR;Y(0.004)GPADVEDT(0.137)T(0.137)GS(0.117)GAT(0.117)DS(0.302)KDDDDIDLFGS(0.183)DDEEES(0.003)EEAKR;YGPADVEDT(0.069)T(0.069)GS(0.186)GAT(0.056)DS(0.508)KDDDDIDLFGS(0.112)DDEEESEEAKR ;;; 64.685 1.51E-05 871253100 5670.64 4324.32 4923.04 5355.22 4730.01 5714.02 4817.17 5096.1 5498.66 4820.14 TRUE FALSE FALSE 5221.80286 4698.094952 5105.492193 5333.061519 4673.60772 4528.867842 4952.326825 6649.87743 4895.470755 4987.639506 1.046948733 0.941947578 1.02362895 1.069255609 0.937037994 0.908018279 0.992919961 1.333271465 0.981520567 1 12.28414148 -4.260061757 24.65749022 1.005723175 1.333271595 0.80535581 0.050169919 34.71980325 621353.2117 0.007365112 0.06164201 5.49E-05 4.260061757 0.32754842 YGPADVEDTTGSGATDSKDDDDIDLFGS(ph)DDEEESEEAK ddPTM_HeLa_Curcumin_4h_R1 2 YGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAK 38 1 P24534;C9JZW3 P24534 EEF1B2 Elongation factor 1-beta 1 0 YGPADVEDTTGSGATDSKDDDDIDLFGS(0.992)DDEEES(0.007)EEAK;YGPADVEDTTGSGATDSKDDDDIDLFGS(0.987)DDEEES(0.012)EEAK ; 93.657 3.77E-14 324770000 11971.8 13447 13327.7 12143.7 11324.6 13269.7 11827.6 11747.5 13269.4 15404.9 TRUE FALSE FALSE 11024.2194 14609.29876 13821.63629 12093.45259 11189.56154 10517.41464 12159.45062 15329.25867 11813.78002 15940.21913 0.691597732 0.916505516 0.867091988 0.758675429 0.701970371 0.659803642 0.762815776 0.961671765 0.74113034 1 13.96038384 -6.257587845 22.38665815 0.857183122 0.758855577 0.09368538 0.109132075 141.179798 820582.4606 0.02053869 0.03317679 5.53E-07 6.257587845 -0.098327544 YGPADVEDTTGSGATDSKDDDDIDLFGS(ph)DDEEESEEAKR ddPTM_HeLa_Curcumin_4h_R1 9 YGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKR 39 2 P24534;C9JZW3 P24534 EEF1B2 Elongation factor 1-beta 1 0 YGPADVEDT(0.006)T(0.006)GS(0.015)GAT(0.006)DS(0.039)KDDDDIDLFGS(0.926)DDEEES(0.002)EEAKR;Y(0.001)GPADVEDT(0.084)T(0.084)GS(0.077)GAT(0.079)DS(0.074)KDDDDIDLFGS(0.599)DDEEES(0.002)EEAKR;YGPADVEDT(0.02)T(0.02)GS(0.059)GAT(0.063)DS(0.055)KDDDDIDLFGS(0.778)DDEEES(0.006)EEAKR;YGPADVEDT(0.003)T(0.003)GS(0.006)GAT(0.009)DS(0.023)KDDDDIDLFGS(0.944)DDEEES(0.01)EEAKR;YGPADVEDT(0.083)T(0.083)GS(0.072)GAT(0.072)DS(0.187)KDDDDIDLFGS(0.5)DDEEES(0.002)EEAKR;YGPADVEDT(0.004)T(0.004)GS(0.011)GAT(0.011)DS(0.041)KDDDDIDLFGS(0.928)DDEEESEEAKR;YGPADVEDT(0.002)T(0.004)GS(0.01)GAT(0.025)DS(0.172)KDDDDIDLFGS(0.785)DDEEES(0.003)EEAKR;Y(0.002)GPADVEDT(0.043)T(0.043)GS(0.014)GAT(0.014)DS(0.027)KDDDDIDLFGS(0.853)DDEEES(0.004)EEAKR;Y(0.003)GPADVEDT(0.056)T(0.056)GS(0.05)GAT(0.153)DS(0.302)KDDDDIDLFGS(0.375)DDEEES(0.004)EEAKR ;;;;;;;; 68.271 8.61E-07 2701459400 16215.52 12998.66 13919.41 14535.2 14531.89 17598.43 14388.91 14764.08 17023.37 14630.83 TRUE FALSE FALSE 14932.04448 14122.20625 14435.27558 14475.05719 14358.6067 13948.31724 14792.62409 19265.58003 15155.9489 15139.25025 0.98631334 0.932820715 0.953500031 0.956127744 0.948435785 0.921334743 0.977104139 1.272558396 1.001103004 1 13.88600614 -4.261554872 9.115152951 0.975522379 1.273784246 0.916210351 0.027793248 0.019508727 34.2151126 0.004598231 0.035811307 5.48E-05 4.261554872 0.298261866 YGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKR ddPTM_HeLa_Curcumin_4h_R1 1 YGPADVEDTTGSGATDSKDDDDIDLFGSDDEEESEEAKR 39 2 P24534;C9JZW3 P24534 EEF1B2 Elongation factor 1-beta 0 0 52.183 0.0010648 14524000 808.46 619.73 642.59 646.67 630.21 666.94 571.48 814.6 718.49 536.79 FALSE FALSE TRUE 744.4695379 673.2966997 666.4049507 643.9942509 622.6951574 528.609126 587.5141907 1062.96779 639.6734446 555.4434125 1.340315721 1.212178747 1.199771094 1.15942369 1.121077581 0.951688532 1.057739056 1.913728322 1.151644668 1 9.11749613 -9.510738229 1.257752838 0.999822726 1.232777536 0.054573296 0.249833728 0.832002955 2.353092969 0.165985528 0.039924025 3.09E-10 9.510738229 0.23295481 YGPLS(ph)EPGSAR ddPTM_HeLa_Curcumin_4h_R1 2 YGPLSEPGSAR 11 0 Q9H1Z4 Q9H1Z4 WDR13 WD repeat-containing protein 13 1 0 YGPLS(0.841)EPGS(0.159)AR;Y(0.022)GPLS(0.978)EPGSAR ; 102.05 0.0098405 111993000 5012.9 5120 4405.1 4594.3 4908.9 4267.7 4189.7 3724.7 5071.9 5691.6 TRUE FALSE FALSE 4616.123675 5562.549986 4568.356881 4575.290004 4850.364574 3382.530913 4307.251706 4860.343884 4515.525259 5889.382676 0.783804336 0.944504762 0.775693673 0.776870897 0.823577757 0.574343883 0.731358776 0.825272215 0.766723018 1 12.5239007 -13.52287875 0.14269959 1.841117126 0.681377406 0.01944378 0.108566229 40.08156897 0.395770324 9.472691721 0.224280517 3.00E-14 13.52287875 -1.159739721 YGPRTPVS(ph)DDAESTSMFDMR ddPTM_HeLa_Curcumin_4h_R1 1 YGPRTPVSDDAESTSMFDMR 20 1 Q9UPQ0-8;Q9UPQ0-10;Q9UPQ0-3;Q9UPQ0;H0Y8P3;Q9UPQ0-2;G5EA03;Q9UPQ0-6;D6RD46 Q9UPQ0-8 LIMCH1 LIM and calponin homology domains-containing protein 1 1 0 Y(0.012)GPRT(0.362)PVS(0.595)DDAES(0.016)T(0.016)SMFDMR 89.659 0.00243 0 1780.1 1409.5 1584.8 1652.1 1847.2 2337.5 1892.2 2265.1 2122 1911.9 TRUE FALSE FALSE 1639.203207 1531.330899 1643.534082 1645.264048 1825.173346 1852.676151 1945.290039 2955.718563 1889.221909 1978.338383 0.828575749 0.774049027 0.830764897 0.831639351 0.922578949 0.936480921 0.983294899 1.494040953 0.954953877 1 10.9500735 -4.15969197 2.152659141 0.894993751 1.76970463 0.880810203 0.066780217 0.3035486 1.234381702 0.012246702 0.559602484 6.92E-05 4.15969197 0.874710879 YGQNCHK(ac)GPPHSK ddPTM_HeLa_Curcumin_4h_R1 2 YGQNCHKGPPHSK 13 1 O15355 O15355 PPM1G Protein phosphatase 1G 0 1 ; YGQNCHK(1)GPPHSK;YGQNCHK(1)GPPHSK 103.97 0.0005121 3270700 2248.9 2038.27 1853.93 2199.9 2061.92 2160.7 1662.62 1440.62 2762.4 2002.32 FALSE TRUE FALSE 2070.897192 2214.448976 1922.638277 2190.797397 2037.332951 1712.546464 1709.268642 1879.858406 2459.371631 2071.900471 0.999515769 1.068800846 0.927958801 1.057385443 0.983316032 0.826558268 0.824976231 0.907311153 1.187012439 1 11.01673899 -5.317960351 5.542568655 1.003520997 0.850195641 0.546653297 0.07159265 0.069744415 4.686578913 0.005372693 0.01233736 4.81E-06 5.317960351 -0.153325356 QETVADFT(ph)PK ddPTM_HeLa_Curcumin_4h_R1 1 QETVADFTPK 10 0 O75400-2;O75400-3;O75400;F5H578 O75400-2 PRPF40A Pre-mRNA-processing factor 40 homolog A 1 0 QETVADFT(1)PK 128.54 0.0090627 27301000 6071.6 5916.6 7838 5756.4 10141 8110.6 10229 12137 4776 4766.3 TRUE FALSE FALSE 5591.026453 6428.00454 8128.483175 5732.581542 10020.0752 6428.370135 10515.99821 15837.51543 4252.084749 4931.92857 1.133638976 1.30334502 1.648134814 1.162340748 2.031674842 1.303419148 2.132228409 3.211221574 0.862154569 1 12.26793619 -1 0.43144669 1.083131716 41.34604809 0.813899745 0.291083242 19.4108155 0.217325799 0.06033687 686.4744517 0.1 1 40.26291637 up YGS(ph)IVDDER ddPTM_HeLa_Curcumin_4h_R1 2 YGSIVDDER 9 0 Q13576 Q13576 IQGAP2 Ras GTPase-activating-like protein IQGAP2 1 0 YGS(1)IVDDER;YGS(1)IVDDER ; 112.83 0.008235 9361700 2692.3 2391.1 2677 2415.9 3254.7 4257.1 3750.5 6388.1 2898.1 2840.4 TRUE FALSE FALSE 2479.201614 2597.776029 2776.211975 2405.903646 3215.889828 3374.129473 3855.728936 8335.802283 2580.185681 2939.103689 0.843523018 0.883866751 0.944577759 0.818584133 1.094173656 1.148013078 1.311872375 2.836171556 0.877881815 1 11.52116054 RDS(ph)LTGSSDLYK ddPTM_HeLa_Curcumin_4h_R1 1 RDSLTGSSDLYK 12 1 Q5T1Z4;Q5T1Z8;Q14671-2;Q14671;Q14671-3;E9PR38;Q14671-4;H0YDK8 Q5T1Z4 PUM1 Pumilio homolog 1 1 0 RDS(1)LTGSSDLYK 142.95 0.0016027 60712000 2243.2 2169.6 2079.5 1917.5 2529.2 2862.7 2507.5 2668.7 1920.1 1611.3 TRUE FALSE FALSE 2065.648353 2357.130556 2156.568099 1909.565893 2499.040942 2268.943751 2577.853701 3482.374345 1709.469834 1667.292555 1.238923755 1.413747425 1.293455124 1.145309434 1.498861693 1.360855204 1.546131597 2.088640253 1.025296867 1 10.70329156 -1 0.311761601 1.09345314 9.007714105 0.798847633 0.134140308 16.69709573 0.213347754 0.049908581 75.71762412 0.1 1 7.914260965 up YGS(ph)QEHPIGDK ddPTM_HeLa_Curcumin_4h_R1 1 YGSQEHPIGDK 11 0 Q14644-2;Q14644 Q14644-2 RASA3 Ras GTPase-activating protein 3 1 0 Y(0.001)GS(0.999)QEHPIGDK 110.44 0.0057832 0 2797.6 2128 1694.3 2029.1 2157.2 2840.2 2370.4 2031.2 2404.9 1783.2 TRUE FALSE FALSE 2576.167008 2311.934838 1757.092248 2020.704122 2131.476799 2251.110504 2436.907044 2650.50353 2141.088487 1845.166067 1.396170813 1.252968434 0.952267809 1.095134014 1.155168002 1.220004283 1.320697951 1.436457984 1.16037712 1 10.84953495 -9.61595072 1.440159342 1.000631594 1.242014839 0.10714577 0.14271127 0.467113675 1.746878438 0.107185371 0.02488197 2.42E-10 9.61595072 0.241383245 DGGGLAPPPGSCS(ph)PSLSPSSNR ddPTM_HeLa_Curcumin_4h_R1 1 DGGGLAPPPGSCSPSLSPSSNR 22 0 A8MUP8;P10276-3;P10276-2;P10276 A8MUP8 RARA Retinoic acid receptor alpha 1 0 DGGGLAPPPGS(0.462)CS(0.5)PS(0.038)LSPSSNR 169.77 1.02E-08 6717300 3022.6 2517.5 2754.5 2916.9 2737.2 2793.8 2002.2 1224.3 2717.8 3126.7 TRUE FALSE FALSE 2783.358021 2735.101482 2856.584193 2904.830641 2704.560678 2214.334387 2058.376343 1597.583434 2419.66414 3235.352592 0.860295112 0.845379724 0.882928247 0.897840516 0.83594001 0.684418259 0.636213916 0.493789591 0.747882671 1 11.65970723 -3.797638064 0.404113465 0.944852859 4.26E-21 0.723685412 0.074110597 1.828534157 0.154709247 0.014494929 0.900827186 0.000159354 3.797638064 -0.944852859 down YGVIILDEAHER ddPTM_HeLa_Curcumin_4h_R1 5 YGVIILDEAHER 12 0 O43143 O43143 DHX15 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 0 0 ;;;; ;;;; 151.13 0.00038254 27135600 19272 16177.9 16665.7 16888.4 16258.5 19521.9 15853.82 14058.9 19515.8 16890.7 FALSE FALSE TRUE 17746.60086 17576.24559 17283.3455 16818.52028 16064.62801 15472.83788 16298.63552 18345.39389 17374.96557 17477.65057 1.015388241 1.005641206 0.988882655 0.962287249 0.919152603 0.885292781 0.93254156 1.04964874 0.994124782 1 14.09322364 -6.275998188 2.340104175 1.007100932 0.941534264 0.292982447 0.039845496 0.247422654 2.655867517 0.006204528 0.010540429 5.30E-07 6.275998188 -0.065566668 YGVSGYPTLK ddPTM_HeLa_Curcumin_4h_R1 2 YGVSGYPTLK 10 0 H7BZJ3;P30101 H7BZJ3;P30101 PDIA3 Protein disulfide-isomerase A3 0 0 ; ; 106.88 0.0063001 13829000 11872.1 10230 11243.4 12380.1 11948.5 8616.2 7024.7 6363.6 12482.3 11560.9 FALSE FALSE TRUE 10932.41076 11114.23562 11660.09029 12328.87443 11806.02194 6829.102995 7221.794176 8303.832346 11113.02292 11962.64041 0.913879409 0.929078801 0.974708751 1.030614814 0.9869077 0.570869203 0.603695666 0.694147116 0.928977428 1 13.54624824 -5.264237914 24.99360319 0.964387734 0.620983151 0.927055947 0.044139413 47.95158721 428256.0008 0.007108617 0.016581777 5.44E-06 5.264237914 -0.343404582 YGVYEDENYEVGS(ph)DDEEIPFK ddPTM_HeLa_Curcumin_4h_R1 2 YGVYEDENYEVGSDDEEIPFK 21 0 O15541 O15541 RNF113A RING finger protein 113A 1 0 YGVYEDENY(0.002)EVGS(0.998)DDEEIPFK;YGVYEDENY(0.015)EVGS(0.985)DDEEIPFK ; 83.423 0.00045011 70004700 12184.2 10509.6 10669.9 10833.9 11900.9 13820 10933.6 9870.5 12103.8 10983.8 TRUE FALSE FALSE 11219.80771 11418.00299 11065.33588 10789.07219 11758.98954 10953.57622 11240.36739 12879.97001 10776.04342 11365.48623 0.987182377 1.004620723 0.973591068 0.94928382 1.034622655 0.963757818 0.988991334 1.133252881 0.948137475 1 13.47237179 -4.261028458 24.77040205 0.990662684 1.133252928 0.744774977 0.026010215 9.218963343 555498.3216 0.002832552 0.022153789 5.48E-05 4.261028458 0.142590244 YHEEFEK ddPTM_HeLa_Curcumin_4h_R1 5 YHEEFEK 7 0 C9J9W2;Q14847;Q14847-2;Q14847-3 C9J9W2 LASP1 LIM and SH3 domain protein 1 0 0 ;;;; ;;;; 135.77 0.0039609 127795000 46641.9 36489.2 37667.7 39531.8 40252.6 48454.2 37779.9 36442.9 44265.3 38563.8 FALSE FALSE TRUE 42950.1444 39643.16386 39063.6981 39368.22789 39772.61403 38404.25273 38839.90231 47554.17245 39409.50734 39903.88918 1.076339808 0.993466168 0.978944632 0.986576213 0.996710217 0.96241879 0.973336262 1.191717735 0.987610685 1 15.28424174 -9.999935479 2.448508281 0.999552806 1.027384016 0.012622632 0.065441096 1.284536283 13.99817427 0.054314525 0.009749349 1.00E-10 9.999935479 0.02783121 YHGHS(ph)MSDPGVS(ph)YR ddPTM_HeLa_Curcumin_4h_R1 1 YHGHSMSDPGVSYR 14 0 P08559-3;P08559;P08559-2;P08559-4;Q5JPU3;P29803 P08559-3 PDHA1;PDHA2 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial" 2 0 YHGHS(0.689)MS(0.311)DPGVS(0.999)Y(0.001)R 106.76 0.0082692 12550000 2476.8 1093.3 1389.6 2172.1 2040.6 1870.2 950.56 472.58 1855.1 1357.6 TRUE FALSE FALSE 2280.758666 1187.79998 1441.099798 2163.112426 2016.267178 1482.299439 977.2301553 616.6674665 1651.600171 1404.776499 1.623574048 0.845543744 1.025856995 1.539826746 1.435293927 1.055185248 0.695648138 0.43897906 1.175703162 1 10.4561249 -4.741529172 2.290035317 1.272290011 0.47048224 0.558420446 0.23641505 0.205280981 2.032449951 0.041531259 0.221788613 1.81E-05 4.741529172 -0.801807771 YHGHS(ph)MSDPGVSYR ddPTM_HeLa_Curcumin_4h_R1 5 YHGHSMSDPGVSYR 14 0 P08559-3;P08559;P08559-2;P08559-4;Q5JPU3;P29803 P08559-3 PDHA1;PDHA2 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial" 1 0 YHGHS(0.94)MS(0.06)DPGVSYR;YHGHS(0.822)MS(0.178)DPGVSYR;YHGHS(0.738)MS(0.262)DPGVSYR;YHGHS(0.886)MS(0.114)DPGVSYR;YHGHS(0.974)MS(0.026)DPGVSYR ;;;; 154.81 0.00019172 344176000 16937.2 11668.8 12196.2 14093.3 19413.5 24482.8 12862.8 4424.77 18261 12458 TRUE FALSE FALSE 15596.60275 12677.39908 12648.2019 14034.98566 19182.00669 19404.7913 13223.69555 5773.862004 16257.81399 12890.91457 1.209891095 0.983436746 0.981171804 1.088750188 1.488025274 1.505307571 1.025815156 0.447901658 1.261183906 1 13.654067 -9.647071633 1.479495067 0.999987014 1.124157044 0 0.293035828 1.687663743 6.640705335 0.204868447 0.04630796 2.25E-10 9.647071633 0.12417003 REGPGS(ph)EPDSQVDGGLSGASLGEK ddPTM_HeLa_Curcumin_4h_R1 1 REGPGSEPDSQVDGGLSGASLGEK 24 1 Q5JSZ5;A0A494C0D3;H0Y412;A0A494C065 Q5JSZ5 PRRC2B Protein PRRC2B 1 0 REGPGS(0.94)EPDS(0.06)QVDGGLSGASLGEK 83.741 8.57E-05 16874000 2385 2019.7 2313.1 2327 2215.6 2630.7 2017.2 979.82 2426.9 2519.8 TRUE FALSE FALSE 2196.224733 2194.273868 2398.825521 2317.371491 2189.180417 2085.063166 2073.797203 1278.562607 2160.675142 2607.362862 0.84231649 0.841568276 0.920019824 0.888779818 0.839614788 0.799682774 0.795361947 0.490366196 0.82868218 1 11.34837566 -3.789012512 0.754637685 0.914957664 2.45E-36 0.777858526 0.059247801 1.807118944 0.449061314 0.011401249 1.649687788 0.00016255 3.789012512 -0.914957664 down YHLDSSVGGPGPAAGPGGT(ph)RSPR ddPTM_HeLa_Curcumin_4h_R1 1 YHLDSSVGGPGPAAGPGGTRSPR 23 1 Q6ZW31;Q6ZW31-2 Q6ZW31 SYDE1 Rho GTPase-activating protein SYDE1 1 0 YHLDS(0.001)S(0.001)VGGPGPAAGPGGT(0.759)RS(0.239)PR 52.769 0.014341 11337000 903.56 679.62 588.51 921.68 891.96 1290.3 704.78 593.51 908.88 826.09 TRUE FALSE FALSE 832.0422726 738.3633245 610.3206983 917.8663324 881.3239596 1022.677235 724.55423 774.4684668 809.1781379 854.796566 0.973380458 0.863788361 0.713995262 1.073783364 1.031033575 1.19639839 0.847633529 0.906026647 0.946632415 1 9.739437302 YHPDK(ac)NPNEGEK ddPTM_HeLa_Curcumin_4h_R1 2 YHPDKNPNEGEK 12 1 P31689;P31689-2 P31689 DNAJA1 DnaJ homolog subfamily A member 1 0 1 ; YHPDK(1)NPNEGEK;YHPDK(1)NPNEGEK 110.8 0.0039522 5260500 4365.5 6200.2 5489 4401.4 11624 10451.2 8811.6 7891.2 7468.6 3876.3 FALSE TRUE FALSE 4019.966069 6736.11766 5692.427169 4383.188173 11485.39139 8283.503311 9058.829781 10297.19055 6649.313266 4011.001136 1.002235086 1.679410559 1.419203579 1.092791556 2.863472485 2.065195952 2.25849594 2.567237007 1.657768981 1 11.96974666 -6.043773303 0.753373175 1.000520591 2.501433382 0.537642505 0.426865799 0.267411901 0.288591812 0.069285769 0.203602596 9.04E-07 6.043773303 1.500912791 YHPDKNPNEGEK ddPTM_HeLa_Curcumin_4h_R1 1 YHPDKNPNEGEK 12 1 P31689;P31689-2 P31689 DNAJA1 DnaJ homolog subfamily A member 1 0 0 70.412 0.011144 2663000 2998.8 2614.4 3464.8 2483.5 3504.6 3311.5 2554.4 2447 2212.5 2883.8 FALSE FALSE TRUE 2761.441816 2840.377086 3593.208536 2473.223935 3462.809934 2624.657572 2626.069589 3193.079035 1969.794285 2984.011835 0.925412488 0.951865221 1.204153581 0.828825109 1.16045449 0.879573446 0.88004664 1.070062457 0.66011611 1 11.54303754 -4.175303709 20.05209402 0.973284232 1.070087596 0.027262802 0.151067946 51561.72867 11992099.32 0.014212907 213.3874233 6.68E-05 4.175303709 0.096803364 YHPGYFGK ddPTM_HeLa_Curcumin_4h_R1 4 YHPGYFGK 8 0 E9PLL6;P46776 E9PLL6 RPL27A 60S ribosomal protein L27a 0 0 ;;; ;;; 94.262 0.0094117 96190200 31433.5 24099.8 29779.2 25499.8 31246.8 33596.9 27747.6 26715.2 23937.7 25487.7 FALSE FALSE TRUE 28945.50531 26182.87933 30882.84335 25394.28858 30874.20232 26628.52422 28526.12298 34860.5415 21311.7942 26373.39568 1.097526677 0.992776192 1.17098472 0.962875198 1.170657078 1.009673709 1.081624957 1.321807094 0.808079265 1 14.68679572 -4.267565432 4.04735458 1.05285515 1.343806017 0.405335339 0.103029388 0.114723889 3.976265436 0.008852119 0.096425823 5.40E-05 4.267565432 0.290950867 YHTINGHNAEVR ddPTM_HeLa_Curcumin_4h_R1 5 YHTINGHNAEVR 12 0 P22626;P22626-2;A0A087WUI2 P22626 HNRNPA2B1 Heterogeneous nuclear ribonucleoproteins A2/B1 0 0 ;;;; ;;;; 174.23 3.05E-06 43846100 6418.33 4692.02 4962.65 4616.01 6545.75 9132.29 6383.34 5906.06 6194.76 5398.21 FALSE FALSE TRUE 5910.312408 5097.577302 5146.570175 4596.910174 6467.696206 7238.150112 6562.439341 7706.790506 5515.210327 5585.797396 1.058096452 0.912596169 0.921367141 0.822964001 1.157882348 1.29581322 1.174843782 1.379711787 0.987363117 1 12.44754753 -5.54212501 8.859287429 0.99652004 1.265214314 0.758489926 0.083019687 0.09365843 37.79381685 0.01294751 0.026198804 2.87E-06 5.54212501 0.268694275 YHTVNGHNCEVR ddPTM_HeLa_Curcumin_4h_R1 2 YHTVNGHNCEVR 12 0 F8W6I7;P09651-2;P09651;P09651-3;F8VTQ5;F8VZ49;A0A2R8Y4L2;H0YH80 F8W6I7 HNRNPA1 "Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed" 0 0 ; ; 109.39 0.00064607 11925500 1583.88 1501.47 1346.85 1233.61 1599.19 2675.08 1571.65 1395.87 1803.55 1522.62 FALSE FALSE TRUE 1458.514227 1631.250376 1396.765446 1228.505649 1580.120704 2120.238254 1615.746269 1821.464337 1605.705077 1575.530932 0.925728716 1.035365504 0.886536353 0.779740736 1.002913159 1.345729374 1.025524943 1.156095574 1.019151732 1 10.62162236 -5.503697242 24.83470174 0.949452008 1.163018127 0.52154083 0.100226277 433.2788658 560974.7864 0.013706538 0.030198471 3.14E-06 5.503697242 0.213566119 YHVLVNLGK ddPTM_HeLa_Curcumin_4h_R1 1 YHVLVNLGK 9 0 O75643;A0A494C1A5;O75643-2 O75643 SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 0 0 74.301 0.018355 2340200 2736.5 1919.3 2556 2418.3 2714.8 3470.6 2562.2 2453 2483.2 2340.1 FALSE FALSE TRUE 2519.903137 2085.19574 2650.727608 2408.293715 2682.427783 2750.758438 2634.088436 3200.908408 2210.799173 2421.418301 1.040672376 0.861146436 1.094700411 0.994579794 1.107791984 1.136011253 1.087828747 1.321914684 0.91301828 1 11.24163661 -1.00000004 0.527155253 1.010152307 12.12410544 0.647136813 0.072231848 47.16654698 0.420961312 0.01167951 591.0019712 0.099999991 1.00000004 11.11395313 YHYLGGR ddPTM_HeLa_Curcumin_4h_R1 1 YHYLGGR 7 0 Q8NCW5-2;Q8NCW5 Q8NCW5-2 APOA1BP NAD(P)H-hydrate epimerase 0 0 102.98 0.014347 4029100 2495.1 1685.7 1967.2 1505.7 1815.5 2340.6 1631.1 1891.4 2100.9 2103.4 FALSE FALSE TRUE 2297.610202 1831.404397 2040.106163 1499.469812 1793.851348 1855.133176 1676.864276 2468.079153 1870.436526 2176.492993 1.055647874 0.841447412 0.937336425 0.688938497 0.824193486 0.852349712 0.770443223 1.13397064 0.859380909 1 11.08778966 -7.258120186 24.8040415 1.026278164 0.854588439 0.089439163 0.122446452 204.8868694 1531102.155 0.017436024 0.020893897 5.52E-08 7.258120186 -0.171689725 YIASVQGST(ph)PS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 2 YIASVQGSTPSPR 13 0 P49792;F8WBP7 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 2 0 YIASVQGS(0.108)T(0.982)PS(0.91)PR;YIASVQGS(0.093)T(0.911)PS(0.997)PR ; 118.52 0.0119 45815000 6776.5 5704.4 5887.3 5159.9 6159.3 10286.9 8480.9 2548.6 6210.3 4698.3 TRUE FALSE FALSE 6240.132874 6197.462918 6105.488517 5138.549701 6085.85437 8153.280983 8718.851229 3325.656408 5529.045627 4861.565575 1.283564477 1.274787478 1.255868798 1.056974265 1.251830151 1.677089583 1.793424586 0.684071079 1.137297346 1 12.24720527 -10.53922528 0.239457843 0.629091517 1.365903967 0.063584744 0.2921556 17.3381219 0.787472531 3.861347833 0.237947625 2.89E-11 10.53922528 0.73681245 YIASVQGSTPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 YIASVQGSTPSPR 13 0 P49792;F8WBP7 P49792 RANBP2 E3 SUMO-protein ligase RanBP2 1 0 YIASVQGSTPS(1)PR 180.61 0.00014288 11528000 1208.8 1110.6 1251.1 1123 1286.4 1771.3 1334 696.59 1429.6 1144.9 TRUE FALSE FALSE 1113.122204 1206.595315 1297.466867 1118.353324 1271.06052 1403.912413 1371.42845 908.9770843 1272.776457 1184.68519 0.939593247 1.018494471 1.095199702 0.944008867 1.072909944 1.185051038 1.157631126 0.767273105 1.074358376 1 10.21028802 -7.028292673 7.918985465 0.971802564 1.047492137 0 0.116429658 0.454577594 111.050143 0.017833368 0.022190356 9.37E-08 7.028292673 0.075689572 YIDLEPDTPLS(ph)PEELKEK ddPTM_HeLa_Curcumin_4h_R1 1 YIDLEPDTPLSPEELKEK 18 1 A0A1B0GUN5;Q5VTI5;Q9Y2H5 A0A1B0GUN5 PLEKHA6 Pleckstrin homology domain-containing family A member 6 1 0 YIDLEPDT(0.004)PLS(0.996)PEELKEK 143.95 9.93E-05 15348000 14272 11426 10890 12002 12572 18463 12724 10930 14115 10202 TRUE FALSE FALSE 13142.35614 12413.61253 11293.59298 11952.3389 12422.08711 14633.56568 13081.0012 14262.50668 12566.61981 10556.51874 1.244951718 1.175919148 1.069821715 1.132223529 1.17672193 1.386211311 1.239139674 1.351061561 1.190413253 1 13.36584653 -13.52287875 0.103629302 0.293114323 1.383259183 0.279600588 0.094395337 73.89537539 0.568352571 11.49547278 0.696651824 3.00E-14 13.52287875 1.09014486 YIDQEELNK ddPTM_HeLa_Curcumin_4h_R1 1 YIDQEELNK 9 0 P08238;Q58FF8;P07900;P07900-2;Q14568 P08238;P07900 HSP90AB1;HSP90AB2P;HSP90AA1;HSP90AA2P Heat shock protein HSP 90-beta;Putative heat shock protein HSP 90-beta 2;Heat shock protein HSP 90-alpha;Heat shock protein HSP 90-alpha A2 0 0 131.5 0.00053583 60494000 4533.2 3585.5 4363.8 4132.2 4412.5 5661.7 3336.2 3974.4 4987.4 4676.3 FALSE FALSE TRUE 4174.392437 3895.414643 4525.526267 4115.102051 4359.883819 4487.399599 3429.804793 5186.176264 4440.294698 4838.801077 0.862691475 0.805037153 0.935257762 0.85043836 0.901025636 0.9273784 0.708812935 1.071789516 0.917643571 1 12.24043392 -9.205883647 0.922784019 1.000805701 0.877119711 0.069351291 0.092125539 0.661756998 1.004147279 0.054728066 0.014993434 6.22E-10 9.205883647 -0.12368599 YIEIDS(ph)DEEPR ddPTM_HeLa_Curcumin_4h_R1 4 YIEIDSDEEPR 11 0 E7EW05;Q9NVU7-2;Q9NVU7 E7EW05 SDAD1 Protein SDA1 homolog 1 0 YIEIDS(1)DEEPR;YIEIDS(1)DEEPR;Y(0.001)IEIDS(0.999)DEEPR;YIEIDS(1)DEEPR ;;; 174.21 0.00021557 74333000 7982.25 6846.08 7727.86 7474.03 8887.4 8823.81 7263.7 4432.82 7501.77 6288.91 TRUE FALSE FALSE 7350.44649 7437.82465 8014.26129 7443.104444 8781.42356 6993.652341 7467.499873 5784.366412 6678.8446 6507.449154 1.129543438 1.142970844 1.231551888 1.14378219 1.349441748 1.074714865 1.147531036 0.888883843 1.026338346 1 12.66787642 -8.793710825 0.788341901 1.004026076 1.147320594 0.167480654 0.109962128 0.760375705 0.915795653 0.059795314 0.02267298 1.61E-09 8.793710825 0.143294518 YIEIDS(ph)DEEPRGELLSLR ddPTM_HeLa_Curcumin_4h_R1 3 YIEIDSDEEPRGELLSLR 18 1 E7EW05;Q9NVU7-2;Q9NVU7 E7EW05 SDAD1 Protein SDA1 homolog 1 0 YIEIDS(1)DEEPRGELLSLR;YIEIDS(1)DEEPRGELLSLR;Y(0.001)IEIDS(0.996)DEEPRGELLS(0.003)LR ;; 131.9 0.00010634 204721000 6272.5 5058.4 6067.5 6350 5645 6776.4 5302.4 4103.2 6996.7 5428.8 TRUE FALSE FALSE 5776.025006 5495.625556 6292.366888 6323.725383 5577.687062 5370.898254 5451.171073 5354.246791 6229.179515 5617.450396 1.028228929 0.978313144 1.120146409 1.125728745 0.992921462 0.956109601 0.970399503 0.953145362 1.108898001 1 12.45569976 -5.525735298 24.99959111 1.027955906 0.963199485 0.346639727 0.052971164 92.1493061 806459.7395 0.007437719 0.014944264 2.98E-06 5.525735298 -0.064756421 YIQHTYR ddPTM_HeLa_Curcumin_4h_R1 1 YIQHTYR 7 0 J3KTF8;J3QQX2;P52565;J3KRY1;P52565-2 J3KTF8 ARHGDIA Rho GDP-dissociation inhibitor 1 0 0 104.37 0.014039 3368900 2692.2 1393.9 2163.5 1580 2337.1 4135.3 3138.4 3169.7 1718.7 2393.1 FALSE FALSE TRUE 2479.109529 1514.382505 2243.681213 1573.462379 2309.231609 3277.592166 3226.455057 4136.126938 1530.16291 2476.260047 1.00115072 0.611560368 0.906076571 0.635418877 0.932548103 1.323605802 1.302954858 1.670312027 0.617933045 1 11.27394711 -4.887483801 1.624127818 0.932211659 1.57964803 0.668584676 0.189974292 0.212091689 0.993443184 0.025933259 0.14814312 1.30E-05 4.887483801 0.647436372 YISENES(ph)PRPSQK ddPTM_HeLa_Curcumin_4h_R1 1 YISENESPRPSQK 13 1 O94782 O94782 USP1 Ubiquitin carboxyl-terminal hydrolase 1 1 0 YIS(0.001)ENES(0.575)PRPS(0.424)QK 131.08 0.015092 12563000 3092.2 2464.5 2555.7 2755.1 2818.6 3167.3 1858.2 944.88 2759.3 1986.6 TRUE FALSE FALSE 2847.449107 2677.520398 2650.41649 2743.700126 2784.990036 2510.366277 1910.336091 1232.969562 2456.611693 2055.634202 1.385192513 1.302527656 1.289342475 1.334721967 1.354808182 1.221212546 0.929317137 0.599800082 1.195062668 1 11.00536785 -4.473741491 2.317529971 1.227809546 0.570084288 0.789116047 0.108071579 0.204958683 1.736762687 0.023046171 0.224516239 3.36E-05 4.473741491 -0.657725258 YISLIYTNYEAGKDDYVK ddPTM_HeLa_Curcumin_4h_R1 1 YISLIYTNYEAGKDDYVK 18 1 P09211 P09211 GSTP1 Glutathione S-transferase P 0 0 67.416 0.014313 11866000 1084.4 1029.8 1028.8 991.6 1003.5 1635.2 1296.7 885.14 1356.1 1206.1 FALSE FALSE TRUE 998.5685957 1118.811323 1066.928233 987.4970219 991.5339179 1296.041087 1333.081912 1155.015111 1207.339223 1248.011885 0.800127473 0.896474895 0.854902302 0.791256104 0.794490765 1.038484571 1.068164436 0.925484064 0.967410036 1 10.28541596 -5.241855919 24.77206714 0.883774999 1.016456381 0.410373809 0.075140704 718.1684144 908444.1609 0.013141827 0.033451753 5.73E-06 5.241855919 0.132681382 YISPDQLADLYK ddPTM_HeLa_Curcumin_4h_R1 2 YISPDQLADLYK 12 0 P06733;A0A2R8Y6G6;P06733-2 P06733 ENO1 Alpha-enolase 0 0 ; ; 170.62 1.09E-06 4207200 1599.01 1138.37 2230.16 1626.62 1089.19 1220.78 1440.86 782.63 703.93 133.51 FALSE FALSE TRUE 1472.446671 1236.76563 2312.811691 1619.889477 1076.202121 967.576467 1481.286654 1021.250284 626.7106401 138.1494626 10.65835975 8.952373809 16.74137306 11.72562996 7.790128899 7.003838083 10.72234829 7.392357996 4.536468174 1 7.110086139 -4.797198354 24.76847285 7.369642783 9.057361634 0 4.178264341 657.8971046 455692.1417 0.75723643 2.27183539 1.60E-05 4.797198354 1.687718851 YK(ac)AEDEVQR ddPTM_HeLa_Curcumin_4h_R1 2 YKAEDEVQR 9 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;Q53FA3;P34931 A0A0G2JIW1 HSPA1B;HSPA1A;HSPA1L Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 1-like 0 1 ; YK(1)AEDEVQR;YK(1)AEDEVQR 120.45 2.99E-06 7495300 4708.5 6189.8 4404.5 4041.7 9459.5 11926.8 9228.8 8268.1 10563.6 3929.1 FALSE TRUE FALSE 4335.817257 6724.818731 4567.734645 4024.976516 9346.701641 9453.047237 9487.73529 10789.00563 9404.799509 4065.635933 1.066454874 1.654063188 1.123498198 0.989999248 2.298951946 2.325109133 2.333641144 2.653706777 2.313241929 1 11.98926532 -5.738897093 6.837535368 1.088578645 2.399416097 0.532405069 0.43833263 0.037523402 6.521764131 0.03174357 0.062484713 1.82E-06 5.738897093 1.310837452 YK(ac)PESEELTAER ddPTM_HeLa_Curcumin_4h_R1 1 YKPESEELTAER 12 1 P07237;H7BZ94;I3L398;H0Y3Z3 P07237 P4HB Protein disulfide-isomerase 0 1 YK(1)PESEELTAER 109.72 0.0034235 2012300 880.06 1350.5 1057.7 1283.3 1353.8 1416.8 1349.1 902.45 1672.9 1479.3 FALSE TRUE FALSE 810.4023224 1467.231202 1096.899292 1277.990045 1337.656819 1122.939709 1386.952115 1177.602851 1489.387055 1530.705565 0.529430572 0.958532611 0.716597181 0.834902593 0.873882509 0.733609216 0.906086805 0.769320291 0.973006886 1 10.57998109 YKAEDEVQR ddPTM_HeLa_Curcumin_4h_R1 1 YKAEDEVQR 9 1 A0A0G2JIW1;P0DMV9;P0DMV8;P0DMV8-2;V9GZ37;Q53FA3;P34931 A0A0G2JIW1 HSPA1B;HSPA1A;HSPA1L Heat shock 70 kDa protein 1B;Heat shock 70 kDa protein 1A;Heat shock 70 kDa protein 1-like 0 0 81.525 0.01885 12577000 3493.9 2763.2 3111.5 3594.2 3765.1 4186.9 3342.6 3329.5 3558.5 2985.8 FALSE FALSE TRUE 3217.354128 3002.038695 3226.814927 3579.328153 3720.203642 3318.489744 3436.38436 4344.649223 3168.141453 3089.556328 1.041364451 0.971673074 1.044426638 1.15852497 1.20412229 1.074099124 1.1122582 1.406237259 1.025435731 1 11.59318396 -1 0.368711104 1.013869299 5.247321114 0.683887667 0.06823217 25.14810795 0.309377366 0.01872676 76.26046216 0.1 1 4.233451816 YKDDDDDQLFYTR ddPTM_HeLa_Curcumin_4h_R1 2 YKDDDDDQLFYTR 13 1 H7C2V1;O60568 H7C2V1 PLOD3 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3" 0 0 ; ; 147.52 0.00057106 35255000 7798.7 6759.4 7427.2 7618.8 8244.2 8307.4 5518.8 3668.6 7677.2 7684.6 FALSE FALSE TRUE 7181.424666 7343.652417 7702.458566 7587.275424 8145.893299 6584.351596 5673.642675 4787.139252 6835.030367 7951.639278 0.903137632 0.923539431 0.968662976 0.954177517 1.024429431 0.828049584 0.713518619 0.602031743 0.859575004 1 12.9570366 -4.791902367 2.0048731 0.955974642 0.61622754 0.851006066 0.048687776 0.0860974 0.641682746 0.006604263 0.036364787 1.61E-05 4.791902367 -0.339747102 YKDLDEDELLGNLSET(ph)ELK ddPTM_HeLa_Curcumin_4h_R1 1 YKDLDEDELLGNLSETELK 19 1 Q9NYL9;H0YNU8 Q9NYL9 TMOD3 Tropomodulin-3 1 0 YKDLDEDELLGNLS(0.418)ET(0.582)ELK 75.239 0.005676 121400000 10135 8896.7 9814.6 10060 10135 12824 11260 5833.8 9598.4 8321.1 TRUE FALSE FALSE 9332.804056 9665.691105 10178.33771 10018.37439 10014.14674 10164.15784 11575.9253 7612.498764 8545.479534 8610.257606 1.083916938 1.12257862 1.182117676 1.163539448 1.163048448 1.180470819 1.344434258 0.884119746 0.99247664 1 13.07184069 -7.75081778 0.726622763 1.013696112 1.165894808 0.232502104 0.10677682 0.556274077 0.646051301 0.031114284 0.026506715 1.77E-08 7.75081778 0.152198696 YKDLDEDELLGNLSETELK ddPTM_HeLa_Curcumin_4h_R1 2 YKDLDEDELLGNLSETELK 19 1 Q9NYL9;H0YNU8 Q9NYL9 TMOD3 Tropomodulin-3 0 0 ; ; 133.21 0.00015014 21829000 5736.6 5065.8 5002.6 5367.4 4463.8 6049.6 5129.7 5160.2 4871.2 4839 FALSE FALSE TRUE 5282.542057 5503.665179 5188.000757 5345.191121 4410.5721 4794.844767 5273.625576 6733.521225 4336.841547 5007.15489 1.054998731 1.099160162 1.03611749 1.06751064 0.880853938 0.957598651 1.053217983 1.344779895 0.866128898 1 12.28977537 -4.26833192 4.284994967 1.020919791 1.367413394 0.641888037 0.076014956 0.082708792 3.517084723 0.008471575 0.086279051 5.39E-05 4.26833192 0.346493603 YKDNPFSLGES(ph)FGSR ddPTM_HeLa_Curcumin_4h_R1 2 YKDNPFSLGESFGSR 15 1 Q8N6H7;E9PMU9;H0YDN9;A0A0D9SF70;G5E9L0;Q8N6H7-3;Q8N6H7-2;E9PQP3 Q8N6H7 ARFGAP2 ADP-ribosylation factor GTPase-activating protein 2 1 0 YKDNPFSLGES(0.99)FGS(0.01)R;YKDNPFSLGES(0.5)FGS(0.5)R ; 120.08 0.00057597 47973000 3893.4 2942.24 4078.1 4000.1 3520 5661.3 4410.7 4065.5 4328.5 4533.7 TRUE FALSE FALSE 3585.233282 3196.554115 4229.237973 3983.548646 3478.026299 4487.082564 4534.452371 5305.052235 3853.674379 4691.245738 0.76423907 0.681387055 0.90151704 0.849145167 0.741386509 0.956479966 0.966577456 1.130840832 0.821460779 1 12.19575536 -4.404591811 1.532870264 0.860828789 1.183090578 0.496938565 0.091809072 0.748753832 1.987063683 0.016961867 0.332775088 3.94E-05 4.404591811 0.322261789 YKLDEDEDEDDADLS(ph)KYNLDASEEEDSNK ddPTM_HeLa_Curcumin_4h_R1 1 YKLDEDEDEDDADLSKYNLDASEEEDSNK 29 2 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 YKLDEDEDEDDADLS(0.528)KY(0.46)NLDAS(0.011)EEEDS(0.001)NK 83.09 1.85E-06 33004000 1344.8 1673.8 1641.3 1491.6 1789.6 1882 1529.5 1540.9 1372 1217.6 TRUE FALSE FALSE 1238.357661 1818.475814 1702.128022 1485.428154 1768.260189 1491.651985 1572.413654 2010.713317 1221.495033 1259.911509 0.98289257 1.443336139 1.350990136 1.178994035 1.40347967 1.183933931 1.248034994 1.595916302 0.969508591 1 10.29910669 -7.272583344 24.8638646 0.99192148 1.329980322 0.656898256 0.118703679 287.7309528 641969.8748 0.01907105 0.021915476 5.34E-08 7.272583344 0.338058842 YKLDEDEDEDDADLSK ddPTM_HeLa_Curcumin_4h_R1 1 YKLDEDEDEDDADLSK 16 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 0 0 86.772 0.006882 7979200 2807.3 2745 3210.6 2829.1 3799.4 3249.6 2938.9 3004 2600.4 2518.5 FALSE FALSE TRUE 2585.099243 2982.265569 3329.58766 2817.393934 3754.094636 2575.596329 3021.357624 3919.905771 2315.142626 2606.017688 0.991973023 1.144376565 1.277653516 1.081110826 1.44054841 0.988326496 1.159377252 1.504174661 0.888383313 1 11.34763116 -7.110001278 3.124411419 0.995812247 1.228180951 0.410608494 0.148274015 0.199911175 3.716025096 0.022833605 0.028503617 7.76E-08 7.110001278 0.232368704 YKLDEDEDEDDADLSKYNLDAS(ph)EEEDSNK ddPTM_HeLa_Curcumin_4h_R1 1 YKLDEDEDEDDADLSKYNLDASEEEDSNK 29 2 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 YKLDEDEDEDDADLS(0.115)KY(0.408)NLDAS(0.471)EEEDS(0.006)NK 65.741 0.00012807 132990000 1558.4 1345.4 1786.8 1395 2070.8 1926.1 1886.7 1738.4 1422.4 1743.1 TRUE FALSE FALSE 1435.050996 1461.690381 1853.02038 1389.22786 2046.107062 1526.605148 1939.635724 2268.430157 1266.366279 1803.672595 0.79562721 0.810396734 1.027359613 0.770221748 1.134411571 0.846387062 1.075381269 1.257672908 0.702104297 1 10.81672177 -2.58211154 0.756284479 0.900602841 5.592277262 0.459503268 0.12734971 17.9660837 0.933605219 0.018661418 123.2117218 0.002617511 2.58211154 4.691674421 YKPESEELTAER ddPTM_HeLa_Curcumin_4h_R1 1 YKPESEELTAER 12 1 P07237;H7BZ94;I3L398;H0Y3Z3 P07237 P4HB Protein disulfide-isomerase 0 0 81.676 0.019888 9041400 3468.3 2539.3 3452.1 3235.8 3161.2 3545.7 2908.8 1456.2 2713.1 2919.9 FALSE FALSE TRUE 3193.780395 2758.785777 3580.037863 3222.411117 3123.504755 2810.281852 2990.413099 1900.188676 2415.479718 3021.366308 1.05706494 0.913092123 1.184906926 1.066541024 1.033805384 0.930136093 0.989755228 0.628917014 0.799466027 1 11.56098539 -3.855753999 1.426885324 1.031253873 6.58E-17 0.52118286 0.102112792 1.265075849 1.054991164 0.00989614 2.470987698 0.000139395 3.855753999 -1.031253873 YKPLNTTPNATK(ac)EIK ddPTM_HeLa_Curcumin_4h_R1 2 YKPLNTTPNATKEIK 15 2 Q96QC0 Q96QC0 PPP1R10 Serine/threonine-protein phosphatase 1 regulatory subunit 10 0 1 ; YKPLNTTPNATK(1)EIK;YKPLNTTPNATK(1)EIK 162.59 0.00017673 12150900 4957.9 4941.4 5293.8 4578.4 3755.9 5582.5 3112.8 2770.3 4725.1 5173.2 FALSE TRUE FALSE 4565.476983 5368.512598 5489.992885 4559.455794 3711.113346 4424.626572 3200.13679 3614.951717 4206.768352 5352.968315 0.852886981 1.002903862 1.025597867 0.851762149 0.693281396 0.8265744 0.597824721 0.675317227 0.785875818 1 12.3861234 -5.898969207 3.41555527 0.941979513 0.699120439 0.622252003 0.086159755 0.110804925 2.552184257 0.012306688 0.023339039 1.26E-06 5.898969207 -0.242859073 YKPVCNQVECHPYFNQR ddPTM_HeLa_Curcumin_4h_R1 2 YKPVCNQVECHPYFNQR 17 1 H0Y804;Q04828;S4R3P0;B4DK69;P52895 H0Y804 AKR1C1;AKR1C2 Aldo-keto reductase family 1 member C1;Aldo-keto reductase family 1 member C2 0 0 ; ; 104.09 0.00049847 13067200 6432.1 5256.8 5292 5151.4 5583.7 8594.5 6027.5 6185 6495.1 6300 FALSE FALSE TRUE 5922.992498 5711.174368 5488.126175 5130.084872 5517.118024 6811.90382 6196.615428 8070.778028 5782.60378 6518.924531 0.908584302 0.8760915 0.84187601 0.78695264 0.846323346 1.044942887 0.950557933 1.238053607 0.887048738 1 12.67041826 -3.509555046 1.294111039 0.925062807 2.588448437 0.636440713 0.074636541 4.983102066 1.701462837 0.012783136 17.65330175 0.000309346 3.509555046 1.66338563 YKPVCNQVECHPYFNR ddPTM_HeLa_Curcumin_4h_R1 1 YKPVCNQVECHPYFNR 16 1 S4R3Z2;A0A0A0MSS8;P42330;P42330-2 S4R3Z2 AKR1C3 Aldo-keto reductase family 1 member C3 0 0 82.908 0.0034441 6309000 3134.6 2558.6 2692 2791.4 2588.3 4332 2887.9 2751.1 2771 2834.5 FALSE FALSE TRUE 2886.493102 2779.753983 2791.767888 2779.849926 2557.436213 3433.494368 2968.926702 3589.897725 2467.028233 2932.998664 0.984144022 0.947751534 0.951847651 0.947784246 0.871952737 1.170643005 1.012249592 1.223968415 0.841128318 1 11.5181607 -5.247570733 24.99120738 0.975384313 1.123283267 0.563910721 0.074962437 441.9053144 796308.9523 0.008291485 0.021022434 5.65E-06 5.247570733 0.147898955 YLAADK(ac)DGNVTCER ddPTM_HeLa_Curcumin_4h_R1 2 YLAADKDGNVTCER 14 1 Q16658 Q16658 FSCN1 Fascin 0 1 ; YLAADK(1)DGNVTCER;YLAADK(1)DGNVTCER 215.02 6.19E-27 11471100 2525.8 3290.7 2774.4 2440.9 4960.8 7272.8 5586.8 5305 6476 2679.5 FALSE TRUE FALSE 2325.880265 3575.133445 2877.221705 2430.800203 4901.6457 5764.339299 5743.550572 6922.470079 5765.599002 2772.612426 0.838876809 1.289445799 1.037729499 0.876718354 1.767879872 2.079028156 2.071530272 2.496731968 2.079482494 1 11.43703025 -5.55885649 2.140819042 0.954636878 2.225122382 0.53807688 0.394411146 0.06203568 0.567542959 0.025925133 0.063438511 2.76E-06 5.55885649 1.270485503 YLAADKDGNVTCER ddPTM_HeLa_Curcumin_4h_R1 2 YLAADKDGNVTCER 14 1 Q16658 Q16658 FSCN1 Fascin 0 0 ; ; 94.547 0.0060839 24583000 10122 7336.7 8741.2 9186.1 9035.3 13061.9 9908.9 9319.9 10410.6 9383 FALSE FALSE TRUE 9320.833019 7970.851656 9065.156562 9148.090352 8927.559949 10352.7147 10186.91707 12161.49461 9268.583226 9709.058552 0.960014091 0.820970603 0.933680286 0.942222184 0.919508303 1.066294394 1.049217801 1.25259257 0.95463254 1 13.24511569 -3.991379402 1.075852755 0.959497119 1.540666462 0.74931437 0.054739115 1.241179393 0.776608656 0.009139791 0.940528685 0.000102005 3.991379402 0.581169343 YLAEFATGNDR ddPTM_HeLa_Curcumin_4h_R1 2 YLAEFATGNDR 11 0 P62258;P62258-2;K7EM20 P62258 YWHAE 14-3-3 protein epsilon 0 0 ; ; 97.456 0.013079 4253300 327.88 190.091 332.36 271.87 288 427.24 219.981 366.05 472.25 519.91 FALSE FALSE TRUE 301.927952 206.521619 344.677554 270.745074 284.5657881 338.625608 226.1530748 477.6569599 420.4453565 537.9768338 0.561228538 0.38388571 0.640692187 0.503265302 0.528955468 0.629442732 0.420376976 0.887876447 0.781530598 1 9.071400239 -9.05552277 0.804062639 1.005404179 0.560000169 0.402666767 0.147019302 0.320383291 0.371553121 0.086054933 0.024933483 8.80E-10 9.05552277 -0.44540401 YLAEFATGNDRK ddPTM_HeLa_Curcumin_4h_R1 4 YLAEFATGNDRK 12 1 P62258;P62258-2;K7EM20 P62258 YWHAE 14-3-3 protein epsilon 0 0 ;;; ;;; 110.98 0.003274 214025000 15071.7 13532.7 14727.6 14367.2 12487.9 16386.2 12968.5 12415.6 16713.9 15997 FALSE FALSE TRUE 13878.75904 14702.40629 15273.41781 14307.75233 12338.98995 12987.51741 13332.36121 16201.05929 14880.42699 16552.89456 0.83844907 0.888207572 0.922703746 0.864365582 0.745427931 0.784607028 0.805439868 0.978744789 0.898962229 1 14.0147959 -9.909743191 0.401880288 1.09307143 0.838935466 0.155089378 0.07155907 2.744985072 0.398564303 0.316029425 0.021144557 1.23E-10 9.909743191 -0.254135964 YLAEKYEWDVAEAR ddPTM_HeLa_Curcumin_4h_R1 2 YLAEKYEWDVAEAR 14 1 P13639 P13639 EEF2 Elongation factor 2 0 0 ; ; 119.21 0.0015997 173939000 7019 4605.7 4577.1 5520.4 4256 6372.9 4638.6 5037 7424.1 6581.7 FALSE FALSE TRUE 6463.438744 5003.796185 4746.731352 5497.558048 4205.24998 5051.088703 4768.746632 6572.758113 6609.694804 6810.413585 0.94905231 0.734727212 0.696981364 0.807228222 0.61747351 0.74167136 0.700213955 0.965104106 0.970527666 1 12.7335267 -7.308646829 4.260457259 0.977804296 0.74383348 0.581403695 0.086029873 0.100787703 3.935899142 0.014131643 0.016316411 4.91E-08 7.308646829 -0.233970816 YLAEVAAGDDK(ac)K ddPTM_HeLa_Curcumin_4h_R1 3 YLAEVAAGDDKK 12 1 P63104;E7EX29;B0AZS6;P63104-2;B7Z2E6;H0YB80 P63104 YWHAZ 14-3-3 protein zeta/delta 0 1 ;; YLAEVAAGDDK(1)K;YLAEVAAGDDK(1)K;YLAEVAAGDDK(1)K 206.97 5.59E-21 20233600 6445.62 9317.46 5948.01 5782.51 13263.4 15745.5 12780.93 12140.4 15850.2 6910.02 FALSE TRUE FALSE 5935.442376 10122.81972 6168.448483 5758.583506 13105.24262 12479.70581 13139.5285 15841.95207 14111.47272 7150.142681 0.830115236 1.415750731 0.862702852 0.805380223 1.83286449 1.745378571 1.837659622 2.215613419 1.973593164 1 12.80375632 -5.752881265 21.8749067 0.947333913 1.891257705 0.441054419 0.380686153 11.3638446 29045.05568 0.029105307 0.057308525 1.77E-06 5.752881265 0.943923792 YLAEVAAGDDKK ddPTM_HeLa_Curcumin_4h_R1 3 YLAEVAAGDDKK 12 1 P63104;E7EX29;B0AZS6;P63104-2;B7Z2E6;H0YB80 P63104 YWHAZ 14-3-3 protein zeta/delta 0 0 ;; ;; 109.39 0.0010314 99244000 8539.9 7379.9 8503.4 8485.2 8234.9 8802.1 8096 8173.2 9149 8376.2 FALSE FALSE TRUE 7863.957904 8017.785672 8818.543484 8450.090491 8136.704196 6976.44524 8323.151971 10665.17106 8145.37759 8667.272327 0.907316351 0.925064469 1.017453145 0.974942309 0.938784878 0.8049182 0.96029658 1.230510667 0.939785585 1 13.08136232 -4.264682499 6.068749517 0.947348822 1.237446182 0.70820828 0.055673367 0.057857349 10.5911922 0.008447541 0.069228547 5.44E-05 4.264682499 0.29009736 YLAEVACGDDR ddPTM_HeLa_Curcumin_4h_R1 2 YLAEVACGDDR 11 0 P27348;E9PG15 P27348 YWHAQ 14-3-3 protein theta 0 0 ; ; 123.35 0.0016649 6584100 2131.83 1980.82 1815.73 1932.54 1823.98 2120.2 1682.71 1796.4 2002.5 1835.64 FALSE FALSE TRUE 1963.093406 2152.033254 1883.022551 1924.543662 1802.23023 1680.44662 1729.922314 2344.11409 1782.83076 1899.428353 1.033518007 1.13298996 0.991362769 1.013222561 0.948827697 0.88471177 0.910759445 1.234115562 0.938614377 1 10.89134958 -6.17904778 2.757134364 1.025523662 0.981915569 0.002895184 0.100221343 0.807848386 12.00244923 0.014471521 0.025101866 6.62E-07 6.17904778 -0.043608093 YLAEVACGDDRK ddPTM_HeLa_Curcumin_4h_R1 2 YLAEVACGDDRK 12 1 P27348;E9PG15 P27348 YWHAQ 14-3-3 protein theta 0 0 ; ; 102.05 0.011948 27261300 1844.01 1736.03 1263.06 1563.03 1482.21 2202.5 1539.32 1509.27 2045.53 1765.27 FALSE FALSE TRUE 1698.054663 1886.084698 1309.870115 1556.562596 1464.535614 1745.676673 1582.509176 1969.439475 1821.140477 1826.613001 0.92961928 1.032558455 0.717103247 0.852157844 0.801776629 0.955690489 0.866362593 1.078191973 0.997004004 1 10.83495529 YLAEVATGDDK(ac)KR ddPTM_HeLa_Curcumin_4h_R1 1 YLAEVATGDDKKR 13 2 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 1 YLAEVATGDDK(0.977)K(0.023)R 141.37 0.00011324 9095800 1848.5 2266.5 1711.3 1597.5 2919.4 4647.1 3172.9 3216.2 4729.8 1918.9 FALSE TRUE FALSE 1702.189274 2462.406161 1774.722283 1590.889968 2884.588062 3683.239076 3261.923035 4196.804574 4210.952773 1985.581632 0.85727489 1.240143503 0.893804744 0.801221135 1.452767297 1.85499252 1.642804799 2.113639906 2.120765374 1 10.95534596 -5.533414608 3.072586424 0.945480259 1.843513201 0.31935306 0.403528905 0.061003831 1.178272409 0.022461994 0.050931081 2.93E-06 5.533414608 0.898032942 YLAEVATGDDKKR ddPTM_HeLa_Curcumin_4h_R1 2 YLAEVATGDDKKR 13 2 P31947-2;P31947 P31947-2 SFN 14-3-3 protein sigma 0 0 ; ; 115.91 0.00017255 9714100 10887.6 8426.6 7871.2 8821.4 8763.5 11588.4 9208.3 9486.6 10083.1 9963.7 FALSE FALSE TRUE 10025.83497 9154.957756 8162.913596 8784.899384 8659.000986 9184.835212 9466.660115 12379.02067 8977.009157 10309.93783 0.972443785 0.887974099 0.791751971 0.852080733 0.839869369 0.890872027 0.918207294 1.200688197 0.870714189 1 13.33174801 -7.365948899 4.225599659 0.98811545 0.901554587 0 0.11061934 0.366690524 11.06528804 0.018132296 0.02063314 4.31E-08 7.365948899 -0.086560863 YLAEVATGEK ddPTM_HeLa_Curcumin_4h_R1 1 YLAEVATGEK 10 0 P61981 P61981 YWHAG "14-3-3 protein gamma;14-3-3 protein gamma, N-terminally processed" 0 0 169.65 1.92E-12 3466600 3331.2 2547.2 3085.6 3001.1 3525.6 3316.8 2969.5 2417.8 2555.9 2665.3 FALSE FALSE TRUE 3067.532005 2767.368618 3199.95505 2988.682243 3483.559523 2628.858292 3052.816178 3154.97609 2275.524165 2757.918977 1.112263279 1.003426367 1.160278847 1.083672968 1.263111626 0.953203598 1.106927435 1.143969825 0.825087388 1 11.42936436 -9.734281591 0.447977438 0.951873358 1.108222766 0.31756699 0.096683245 3.449318172 0.692298891 0.260815887 0.021353567 1.84E-10 9.734281591 0.156349408 YLAIAPPIIK ddPTM_HeLa_Curcumin_4h_R1 2 YLAIAPPIIK 10 0 Q16531;F5GY55 Q16531 DDB1 DNA damage-binding protein 1 0 0 ; ; 132.29 3.17E-11 0 819.5 533.865 755.55 734.94 775.67 1024.38 930.03 526.31 568.77 628.61 FALSE FALSE TRUE 754.6357103 580.0099117 783.5513476 731.899013 766.4206419 811.9120409 956.1241388 686.7794962 506.377354 650.4541507 1.160167414 0.891699916 1.20462195 1.125212303 1.17828542 1.248223322 1.469933181 1.055846128 0.778498152 1 9.345303557 -5.795934874 1.1990809 1.067408384 1.277128522 0.313721987 0.152209996 0.403607954 1.14677599 0.019542966 0.052757972 1.60E-06 5.795934874 0.209720138 YLAPSGPSGTLK ddPTM_HeLa_Curcumin_4h_R1 2 YLAPSGPSGTLK 12 0 Q16658 Q16658 FSCN1 Fascin 0 0 ; ; 176.33 1.46E-07 18383500 16668 11218.4 12924.1 12654.8 13556.4 17339.4 13845.5 13206.1 14169.2 13517.5 FALSE FALSE TRUE 15348.71021 12188.06851 13403.07852 12602.43779 13394.74878 13743.01298 14233.96747 17232.5791 12614.87421 13987.23212 1.097337206 0.871371005 0.958236655 0.900995828 0.957641131 0.982539853 1.017640041 1.232022101 0.901884955 1 13.77182288 -4.262481393 5.415125909 1.007826749 1.240496219 0.465427264 0.074128047 0.117202865 12.73051389 0.011258453 0.100778331 5.46E-05 4.262481393 0.23266947 YLDEDTIYHLQPSGR ddPTM_HeLa_Curcumin_4h_R1 2 YLDEDTIYHLQPSGR 15 0 P31153-2;P31153 P31153-2 MAT2A S-adenosylmethionine synthase isoform type-2 0 0 ; ; 230.26 5.45E-21 40179000 9360.9 8256.9 7955.2 8349.4 8573 12073.7 9163.4 7636.4 9891.7 8527.6 FALSE FALSE TRUE 8619.974887 8970.589644 8250.02671 8314.852395 8470.772574 9569.478521 9420.500342 9964.703206 8806.605258 8823.933465 0.976885753 1.016620272 0.934960213 0.942306787 0.959976932 1.084491237 1.067607817 1.129281317 0.998036226 1 13.1072062 -5.250932554 21.77716337 0.981527374 1.091174984 0.782430905 0.028443259 47.47555967 98398.79623 0.004198886 0.010541273 5.61E-06 5.250932554 0.10964761 YLDWAY(ph)RSGGY(ph)K ddPTM_HeLa_Curcumin_4h_R1 1 YLDWAYRSGGYK 12 1 Q9NYH9 Q9NYH9 UTP6 U3 small nucleolar RNA-associated protein 6 homolog 2 0 Y(0.006)LDWAY(0.852)RS(0.144)GGY(0.999)K 65.347 0.016323 2307200 1719.5 1302.8 1586.5 1872.1 1723.9 1613.7 1099.6 1092.5 2007.1 1869.5 TRUE FALSE FALSE 1583.399761 1415.408227 1645.297086 1864.353746 1703.343618 1279.00043 1130.451817 1425.598221 1786.926152 1934.464986 0.818520765 0.731679424 0.850517894 0.96375678 0.880524399 0.661164942 0.584374401 0.736947027 0.923731453 1 10.9177189 -3.589017251 0.06295754 1.337073851 2.97E-14 0.465590912 0.093512595 105.4426176 0.873078703 5.303748934 15.54176933 0.000257622 3.589017251 -1.337073851 YLEES(ph)DEDDLF ddPTM_HeLa_Curcumin_4h_R1 6 YLEESDEDDLF 11 0 P11388;P11388-2;P11388-3;P11388-4;J3QR57 P11388 TOP2A DNA topoisomerase 2-alpha 1 0 YLEES(1)DEDDLF;YLEES(1)DEDDLF;YLEES(1)DEDDLF;YLEES(1)DEDDLF;YLEES(1)DEDDLF;YLEES(1)DEDDLF ;;;;; 156.16 0.00042149 150988600 14774.9 8855.7 12394.8 16691.7 13594.95 16492 12873.4 7911.58 17222.9 14046.01 TRUE FALSE FALSE 13605.45107 9621.147248 12854.16219 16622.63417 13432.8391 13071.3733 13234.59296 10323.78432 15333.59096 14534.1078 0.936105006 0.661970269 0.884413572 1.143698285 0.924228668 0.899358493 0.910588606 0.71031428 1.055007378 1 13.82715489 -13.52287875 0.017446889 2.115551037 6.14E-10 0.164553852 0.124898219 5882.847875 8.284056035 641.7669742 391.7796549 3.00E-14 13.52287875 -2.115551036 YLGGS(ph)MDLSTFDFR ddPTM_HeLa_Curcumin_4h_R1 1 YLGGSMDLSTFDFR 14 0 O95983-2;O95983 O95983-2 MBD3 Methyl-CpG-binding domain protein 3 1 0 YLGGS(1)MDLSTFDFR 98 0.0063106 0 147.29 176.91 207.52 161.82 205.14 272.39 310.22 296.72 281.08 131.57 TRUE FALSE FALSE 135.6318411 192.2013121 215.2108738 161.1504317 202.6938395 215.8932435 318.9239383 387.1885621 250.2462272 136.1420477 0.996252395 1.411770392 1.580781819 1.183693315 1.488840831 1.585794008 2.342582205 2.844004248 1.838125924 1 7.088968904 -1 0.371923037 0.997121669 27.16414221 0.67659928 0.316346893 11.1195415 0.136304566 0.049048254 210.8123719 0.1 1 26.16702054 YLGIPGDKEYCISSDDLFSLPYCPGK ddPTM_HeLa_Curcumin_4h_R1 1 YLGIPGDKEYCISSDDLFSLPYCPGK 26 1 E2QRB9;E9PIR7;F8W809;A0A087WSW9;A0A182DWI3;A0A087WSY9;Q16881-7;Q16881-5;Q16881-2;Q16881-4;Q16881-3;Q16881-6;Q16881 E2QRB9 TXNRD1 "Thioredoxin reductase 1, cytoplasmic" 0 0 52.273 0.011265 5806600 1119.1 637.63 1011.7 684.03 691.7 1714 1143.9 1376 825.92 941.16 FALSE FALSE TRUE 1030.522054 692.743896 1049.194492 681.1996651 683.4519293 1358.497079 1175.994755 1795.536066 735.3186423 973.8652399 1.058177263 0.711334451 1.077350797 0.699480418 0.701793124 1.394953864 1.207553886 1.843721279 0.755051738 1 9.927578341 -4.131267141 1.183652484 0.972077723 2.403409928 0.662565898 0.203118309 0.938635511 0.884668176 0.028513249 1.771224703 7.39E-05 4.131267141 1.431332205 YLGS(ph)PITTVPK ddPTM_HeLa_Curcumin_4h_R1 2 YLGSPITTVPK 11 0 A0A3B3IT42;D6RJC2;P30307-4;P30307-3;P30307-2;P30307 A0A3B3IT42 CDC25C M-phase inducer phosphatase 3 1 0 YLGS(0.806)PIT(0.162)T(0.033)VPK;YLGS(0.962)PIT(0.036)T(0.002)VPK ; 144.1 0.0010752 102203000 6583.8 4884.7 5271.1 5354.3 5439.5 8483.4 7674.2 4961.6 5993.6 4931.7 TRUE FALSE FALSE 6062.685283 5306.911702 5466.451603 5332.145325 5374.637515 6723.847212 7889.517398 6474.369 5336.117075 5103.076208 1.188045217 1.039943651 1.071207127 1.044888437 1.053215217 1.317606663 1.546031663 1.268718854 1.045666743 1 12.31715147 -5.143756061 3.999417376 1.080248439 1.412016913 0.76851069 0.079354805 0.09119253 2.512813834 0.012672654 0.034628329 7.18E-06 5.143756061 0.331768475 YLHDESGLNRR ddPTM_HeLa_Curcumin_4h_R1 3 YLHDESGLNRR 11 1 B5MCX3;Q15019;Q15019-3;Q15019-2;C9J2Q4;H7C310;C9IY94;C9J938;C9JB25 B5MCX3 2-Sep Septin-2 0 0 ;; ;; 79.986 0.0081054 14913500 4844.6 3635.55 4067.4 4202.4 4695.8 6166.2 4626.5 4234.8 4500 3981 FALSE FALSE TRUE 4461.144798 3949.790742 4218.141422 4185.011582 4639.805652 4887.260613 4756.307138 5525.971025 4006.361258 4119.339454 1.082975765 0.958840801 1.023984906 1.015942393 1.126347004 1.186418519 1.154628598 1.341470177 0.972573711 1 12.0081973 -3.640154073 0.568114986 1.028786208 1.789013408 0.821579785 0.047579308 2.208337282 0.293756428 0.009246657 1.297458588 0.000229006 3.640154073 0.7602272 YLIANATNPESK ddPTM_HeLa_Curcumin_4h_R1 2 YLIANATNPESK 12 0 P27348;E9PG15 P27348 YWHAQ 14-3-3 protein theta 0 0 ; ; 205.52 2.01E-20 6329000 5400.9 5150.8 5240.2 4230.3 6040.1 5967.7 5976.2 5340.5 4872.3 5119.6 FALSE FALSE TRUE 4973.413066 5596.0122 5434.406422 4212.796139 5968.075752 4729.93175 6143.876088 6968.793865 4337.82088 5297.505719 0.938821651 1.056348496 1.025842483 0.795241452 1.12658222 0.89286015 1.159767712 1.31548586 0.818842133 1 12.37109752 -4.542037955 3.692983542 0.975043426 1.295641605 0.574191796 0.099649574 0.095602784 2.710541629 0.010909387 0.057568116 2.87E-05 4.542037955 0.32059818 YLIPNATQPESK ddPTM_HeLa_Curcumin_4h_R1 2 YLIPNATQPESK 12 0 P31946-2;P31946 P31946-2 YWHAB "14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed" 0 0 ; ; 213.35 1.30E-21 14782000 9053.8 7284.5 8104.7 7861.8 8959.3 7920.7 7263.7 7452.8 6709 5852.7 FALSE FALSE TRUE 8337.182176 7914.139721 8405.067312 7829.269955 8852.466199 6277.857535 7467.499873 9725.124412 5973.039485 6056.080889 1.376662949 1.306808787 1.387872366 1.292794812 1.461748342 1.036620489 1.233058146 1.605844537 0.98628793 1 12.56416876 -9.275329244 0.85502865 0.985966676 1.330450842 0.486203933 0.140812038 0.493981534 0.606260386 0.113299053 0.026254523 5.30E-10 9.275329244 0.344484166 YLLGDAPVS(ph)PSSQK ddPTM_HeLa_Curcumin_4h_R1 3 YLLGDAPVSPSSQK 14 0 Q9NYB0;A0A590UJT3;H3BMI8 Q9NYB0 TERF2IP Telomeric repeat-binding factor 2-interacting protein 1 1 0 Y(0.029)LLGDAPVS(0.965)PS(0.005)S(0.001)QK;YLLGDAPVS(0.727)PS(0.27)S(0.003)QK;Y(0.002)LLGDAPVS(0.987)PS(0.009)S(0.001)QK ;; 211.7 6.94E-10 626650000 22469.2 17690.5 19425.4 19924.6 19108.3 24313.7 17392.1 11001.9 21760.9 19247.1 TRUE FALSE FALSE 20690.73911 19219.58799 20145.32241 19842.15728 18880.446 19270.76455 17880.07552 14356.32866 19373.78371 19915.93529 1.038903712 0.965035672 1.011517768 0.996295529 0.948006997 0.9676053 0.897777345 0.72084632 0.972778001 1 14.28163561 -3.451259663 0.755845276 1.012441701 1.02E-15 0.904995962 0.026261578 1.409263722 0.237983597 0.004129269 1.616032682 0.000353786 3.451259663 -1.012441701 RDTVSLY(ph)QRT(ph)LEQR ddPTM_HeLa_Curcumin_4h_R1 2 RDTVSLYQRTLEQR 14 2 Q96JK9 Q96JK9 MAML3 Mastermind-like protein 3 2 0 RDTVSLY(1)QRT(1)LEQR;RDTVSLY(1)QRT(1)LEQR ; 112.83 0.0010488 491300000 4863.3 4142.9 4350 5156 5239.9 7567.9 5213.6 6761.5 5863.8 3834.5 TRUE FALSE FALSE 4478.364673 4500.993816 4511.214827 5134.665838 5177.417615 5998.232232 5359.879584 8823.050224 5220.555811 3967.74859 1.128691643 1.134394913 1.136970936 1.294100602 1.304875422 1.511747052 1.350861695 2.223691856 1.315747632 1 11.9541049 -1 0.447635881 1.0628994 23.95007469 0.804724389 0.143750033 17.14396826 0.185915659 0.024535199 361.1840844 0.1 1 22.88717529 up RSS(ph)DSWEVWGSASTNR ddPTM_HeLa_Curcumin_4h_R1 1 RSSDSWEVWGSASTNR 16 1 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHH7 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 0 RS(0.227)S(0.771)DS(0.002)WEVWGSASTNR 115.88 0.00055961 32817000 1251.1 1117.2 1030.5 1260.1 1300 1431.8 1326.3 1531.9 1281 905.1 TRUE FALSE FALSE 1152.074115 1213.76579 1068.691237 1254.88604 1284.498349 1134.82854 1363.512408 1998.969258 1140.477505 936.5521576 1.230122749 1.2959938 1.141090998 1.339899791 1.371518221 1.211708853 1.455885182 2.134391813 1.217740513 1 9.871215532 -1 0.679608992 1.141007751 105.4334979 0.846947961 0.113794285 71.23175117 0.381780293 0.022652632 11265.45119 0.1 1 104.2924901 up YLMEEDEDAYKK ddPTM_HeLa_Curcumin_4h_R1 5 YLMEEDEDAYKK 12 1 P46777;A0A2R8Y6J3 P46777 RPL5 60S ribosomal protein L5 0 0 ;;;; ;;;; 109.16 0.0010537 64961600 12850.7 11297.7 12719.6 12148.2 10958.4 14342 10846.1 9590.18 13919.6 11656.2 FALSE FALSE TRUE 11833.55354 12274.22285 13190.99957 12097.93397 10827.72824 11367.30753 11150.41238 12514.18173 12392.65471 12061.25208 0.981121483 1.017657434 1.093667513 1.0030413 0.897728375 0.942464966 0.92448216 1.037552457 1.027476635 1 13.55809206 -5.816070706 24.89691678 1.002387774 0.948116447 0.319300451 0.045586474 92.9114995 42341.79568 0.006789607 0.012307219 1.53E-06 5.816070706 -0.054271327 YLPHSAGR ddPTM_HeLa_Curcumin_4h_R1 3 YLPHSAGR 8 0 M0R0F0;M0R0R2;P46782 M0R0F0 RPS5 "40S ribosomal protein S5;40S ribosomal protein S5, N-terminally processed" 0 0 ;; ;; 138.83 0.0026089 33037000 12581.6 7953.42 10493.9 9254.4 10960.2 12566.1 9413 8348.7 10536.8 9772.9 FALSE FALSE TRUE 11585.75308 8640.878185 10882.81317 9216.107745 10829.50677 9959.749211 9677.103446 10894.1802 9380.939402 10112.50755 1.145685482 0.854474337 1.076173552 0.911357317 1.070902219 0.984894119 0.956944002 1.077297609 0.927657098 1 13.30385316 -7.298990168 24.9983816 1.06879591 0.992169128 0 0.088233621 749.9979402 499288.2457 0.013689093 0.015654271 5.02E-08 7.298990168 -0.076626782 YLQLAEELIRPER ddPTM_HeLa_Curcumin_4h_R1 1 YLQLAEELIRPER 13 1 Q14566 Q14566 MCM6 DNA replication licensing factor MCM6 0 0 125.03 0.0017614 6789900 2923.6 2492.9 3020.8 3191.5 2436.2 3022.7 2833.7 2733.5 3099.9 2827.1 FALSE FALSE TRUE 2692.193975 2708.375168 3132.753505 3178.294419 2407.149906 2395.757947 2913.205995 3566.931567 2759.848726 2925.341515 0.920300745 0.925832131 1.070901804 1.086469529 0.822861158 0.818966926 0.995851589 1.219321419 0.943427874 1 11.51438934 -7.452188567 0.00267122 4.11E-08 1.941650835 0.012324 0.115891093 155310.7268 357.4518851 129969.5391 129844.3631 3.53E-08 7.452188567 1.941650793 YLS(ph)FT(ph)PPEKDGFPSGTPALNAK ddPTM_HeLa_Curcumin_4h_R1 2 YLSFTPPEKDGFPSGTPALNAK 22 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 2 0 Y(0.051)LS(0.932)FT(0.895)PPEKDGFPS(0.104)GT(0.018)PALNAK;Y(0.037)LS(0.968)FT(0.99)PPEKDGFPS(0.004)GT(0.001)PALNAK ; 92.671 0.00042401 146200000 10163.5 7762.9 8831.9 9926.1 9129.2 12526.5 10257.6 6598.9 10594.2 9752.2 TRUE FALSE FALSE 9359.048251 8433.890485 9159.217983 9885.028428 9020.340252 9928.362697 10545.40065 8610.874232 9432.042765 10091.08822 0.927456786 0.835776112 0.907654138 0.979580022 0.893891724 0.983874333 1.045021153 0.853314731 0.934690348 1 13.30079414 -9.074958612 1.052340345 0.9968 0.931845657 0.018072647 0.062440384 0.716020595 1.519250829 0.030537065 0.011018811 8.41E-10 9.074958612 -0.064954344 YLS(ph)FTPPEK ddPTM_HeLa_Curcumin_4h_R1 3 YLSFTPPEK 9 0 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 0 Y(0.005)LS(0.994)FT(0.001)PPEK;YLS(0.955)FT(0.045)PPEK;YLS(0.76)FT(0.24)PPEK ;; 130.98 0.0037644 608215200 12561.1 10674.1 13415.2 13023.2 14457.6 15004.7 13323.8 9668.2 9978 11050.7 TRUE FALSE FALSE 11566.87568 11596.72164 13912.37911 12969.31345 14285.20256 11892.55608 13697.62997 12615.98967 8883.438364 11434.711 1.0115582 1.014168319 1.216679557 1.134205617 1.249284093 1.040039935 1.197899096 1.103306386 0.776883505 1 13.48113228 -6.780054579 22.73423214 1.006263728 1.156621453 0.51772736 0.091421243 35.32562436 43142.0143 0.008035141 0.010575282 1.66E-07 6.780054579 0.150357725 YLS(ph)FTPPEKDGFPSGTPALNAK ddPTM_HeLa_Curcumin_4h_R1 2 YLSFTPPEKDGFPSGTPALNAK 22 1 Q13177 Q13177 PAK2 Serine/threonine-protein kinase PAK 2;PAK-2p27;PAK-2p34 1 0 YLS(0.682)FT(0.317)PPEKDGFPSGTPALNAK;YLS(0.958)FT(0.042)PPEKDGFPSGTPALNAK ; 108.79 1.39E-05 2115600000 9967.4 9374.9 9777.6 10135.8 8636 12096.8 9849.9 9682.9 10261.7 9972.8 TRUE FALSE FALSE 9178.469772 10185.22458 10139.96646 10093.86075 8533.02134 9587.787321 10126.26168 12635.17164 9136.017184 10319.35406 0.889442277 0.987002144 0.982616393 0.978148505 0.82689491 0.929107313 0.981288328 1.224414975 0.885328397 1 13.33306505 -4.264313884 3.455780528 0.944721201 1.258395544 0.72426324 0.053047271 0.131670969 2.678234087 0.007975237 0.107483244 5.44E-05 4.264313884 0.313674343 YLSADSGDADDS(ph)DADLGSAVK ddPTM_HeLa_Curcumin_4h_R1 1 YLSADSGDADDSDADLGSAVK 21 0 Q15361 Q15361 TTF1 Transcription termination factor 1 1 0 YLSADS(0.013)GDADDS(0.974)DADLGS(0.013)AVK 69.256 0.0015987 6132900 2456.5 2245.9 2292.6 2423.8 2458.4 3236 2135.7 980.64 2746.3 1946.1 TRUE FALSE FALSE 2262.065433 2440.025588 2377.565773 2413.770958 2429.085186 2564.817123 2195.621994 1279.632622 2445.037761 2013.72683 1.123322885 1.211696419 1.180679394 1.198658587 1.206263506 1.273666857 1.090327626 0.63545492 1.214185422 1 10.97565227 -4.264349383 5.708465346 1.11347886 0.620776429 0.743815301 0.088806268 0.066770678 9.186404286 0.015051173 0.127749638 5.44E-05 4.264349383 -0.492702431 YLSDSCS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 YLSDSCSPR 9 0 P83436 P83436 COG7 Conserved oligomeric Golgi complex subunit 7 1 0 YLSDSCS(1)PR 108.31 0.009695 9880000 4710.3 4101.7 4476.4 4801.7 4659 5674.6 4268.3 5638.1 4855.9 4433.8 TRUE FALSE FALSE 4337.474785 4456.232671 4642.299322 4781.831838 4603.444468 4497.623994 4388.05701 7357.130735 4323.219919 4587.87422 0.945421469 0.971306635 1.011862815 1.042276141 1.003393783 0.980328531 0.956446668 1.603603408 0.942314395 1 12.16361012 -4.260006794 24.99999889 0.982059963 1.603603611 0.974668251 0.029979903 14.30391795 249591.3968 0.004565203 0.038491681 5.50E-05 4.260006794 0.621543648 YLSEVASGDNK ddPTM_HeLa_Curcumin_4h_R1 2 YLSEVASGDNK 11 0 P31946-2;P31946 P31946-2 YWHAB "14-3-3 protein beta/alpha;14-3-3 protein beta/alpha, N-terminally processed" 0 0 ; ; 230.06 3.00E-40 17469900 9732 7441 8522.9 7821.1 9225.5 9939.5 9004 8613.4 8181.1 7995.3 FALSE FALSE TRUE 8961.701931 8084.166884 8838.766172 7788.738361 9115.491938 7877.935659 9256.628007 11239.58601 7283.653798 8273.13608 1.083229122 0.977158698 1.06836949 0.941449323 1.101818204 0.952230881 1.118877765 1.358564141 0.880398162 1 13.0142186 -4.321950251 3.067110403 1.030500534 1.388953799 0.688334892 0.071048099 0.101936211 1.491212797 0.007097556 0.081180411 4.76E-05 4.321950251 0.358453264 YLSVPPSPNISTSESRS(ph)PPEGDTTLFLSR ddPTM_HeLa_Curcumin_4h_R1 1 YLSVPPSPNISTSESRSPPEGDTTLFLSR 29 1 Q9BTC0;Q9BTC0-1 Q9BTC0 DIDO1 Death-inducer obliterator 1 1 0 YLSVPPS(0.019)PNIS(0.063)T(0.063)S(0.063)ES(0.063)RS(0.55)PPEGDT(0.077)T(0.077)LFLS(0.022)R 44.161 0.014222 56645000 1763.2 1268.4 1506.6 1392.1 1152.6 1508.3 1406.7 1064.8 1871.9 1515.6 TRUE FALSE FALSE 1623.640859 1378.034844 1562.435921 1386.339859 1138.855998 1195.461578 1446.168216 1389.452618 1666.557253 1568.266987 1.035308957 0.878699134 0.996281841 0.883994798 0.726187573 0.762281925 0.922144142 0.885979638 1.062674447 1 10.61495547 -6.488217402 1.278055831 1.012900082 0.828079666 0.568200921 0.06962239 0.230942137 0.751900256 0.012335344 0.021242797 3.25E-07 6.488217402 -0.184820415 YLTAEAFGFK ddPTM_HeLa_Curcumin_4h_R1 2 YLTAEAFGFK 10 0 Q16658 Q16658 FSCN1 Fascin 0 0 ; ; 161.79 4.22E-09 2196730 2096.07 1634.98 1536.55 1700.12 1679.43 2950.23 2214.29 1876.84 1857.18 1915.38 FALSE FALSE TRUE 1930.163848 1776.300386 1593.495895 1693.085354 1659.403894 2338.319042 2276.417018 2449.079876 1653.452 1981.939312 0.973876362 0.896243581 0.80400842 0.854256911 0.837262717 1.179813644 1.148580587 1.235698722 0.834259652 1 10.95269707 -5.242441612 24.07512039 0.94729997 1.184086018 0.720595436 0.080068039 267.3727773 338829.6992 0.012449188 0.031673583 5.72E-06 5.242441612 0.236786047 YLTNQK(ac)NSNSK ddPTM_HeLa_Curcumin_4h_R1 1 YLTNQKNSNSK 11 1 B1AK63;Q9HAF1-2;Q9HAF1;Q9HAF1-4;Q9HAF1-3 B1AK63 MEAF6 Chromatin modification-related protein MEAF6 0 1 YLTNQK(1)NSNSK 191.33 3.84E-16 48768000 3668.6 2773.2 3106.8 3336 3627.7 4205.9 3193.7 2761.8 3520.4 3033.9 FALSE TRUE FALSE 3378.226439 3012.903051 3221.940741 3322.196516 3584.442047 3333.54893 3283.306627 3603.860106 3134.220928 3139.327799 1.07609866 0.95972872 1.026315488 1.058250915 1.141786483 1.061867108 1.045862948 1.147971903 0.99837326 1 11.61623996 -5.996028335 24.35791646 1.029830511 1.093764558 0.466022796 0.04183698 79.79779668 489383.7346 0.006612617 0.011945412 1.01E-06 5.996028335 0.063934047 YLTNQK(ac)NSNSK(ac)NDR ddPTM_HeLa_Curcumin_4h_R1 2 YLTNQKNSNSKNDR 14 2 B1AK63;Q9HAF1-2;Q9HAF1;Q9HAF1-4;Q9HAF1-3 B1AK63 MEAF6 Chromatin modification-related protein MEAF6 0 2 ; YLTNQK(1)NSNSK(1)NDR;YLTNQK(1)NSNSK(1)NDR 382.57 0 10121200 568.43 638.38 559.48 606.31 667.49 934.52 661.75 584.94 628.05 620.74 FALSE TRUE FALSE 523.4381657 693.5587226 580.214821 603.8012499 659.5306177 740.6900178 680.316924 763.2855133 559.1544863 642.3106688 0.814929895 1.079787019 0.903324278 0.940045494 1.026809377 1.153164744 1.059171141 1.188343196 0.870535885 1 9.32712745 -5.555442191 2.338235205 0.924636539 1.127569023 0.589185693 0.074012362 0.182539613 1.996586378 0.012891061 0.030759247 2.78E-06 5.555442191 0.202932484 YLTNQK(ac)NSNSK(ac)NDRR ddPTM_HeLa_Curcumin_4h_R1 2 YLTNQKNSNSKNDRR 15 3 B1AK63;Q9HAF1-2;Q9HAF1;Q9HAF1-4;Q9HAF1-3 B1AK63 MEAF6 Chromatin modification-related protein MEAF6 0 2 ; YLTNQK(1)NSNSK(1)NDRR;YLTNQK(1)NSNSK(1)NDRR 160.46 9.12E-05 75119000 3891.8 3446.8 3174.3 3474.5 3450.1 5135.6 3329 3146.7 4206.8 3824.8 FALSE TRUE FALSE 3583.759923 3744.726033 3291.94235 3460.12344 3408.959811 4070.41867 3422.40278 4106.114344 3745.324565 3957.711515 0.905513176 0.946184688 0.831779259 0.874273788 0.861346209 1.02847786 0.864742861 1.037497131 0.946335919 1 11.95045074 -9.206468222 0.876681572 1.001601051 0.914844845 0.071660433 0.067448716 0.805701645 1.081952079 0.045876066 0.011952629 6.22E-10 9.206468222 -0.086756206 YLVDGTKPNAGSEEIS(ph)S(ph)EDDELVEEK ddPTM_HeLa_Curcumin_4h_R1 1 YLVDGTKPNAGSEEISSEDDELVEEK 26 1 Q9NY61 Q9NY61 AATF Protein AATF 2 0 YLVDGTKPNAGS(0.006)EEIS(0.997)S(0.996)EDDELVEEK 89.946 2.14E-05 0 1020.3 899.85 974.58 1111.3 1047.1 1347.3 1103.5 808.45 1111.7 909.34 TRUE FALSE FALSE 939.5421784 977.6290243 1010.698792 1106.701735 1034.614016 1067.854793 1134.46124 1054.942683 989.7492913 940.9394973 0.998514975 1.03899244 1.074137917 1.176166734 1.099554243 1.134881462 1.205668636 1.121158891 1.051873467 1 9.87795815 -6.644950438 1.64897014 0.999226074 1.148820643 0.750833407 0.03335716 0.090413448 0.498695795 0.004639201 0.007106354 2.26E-07 6.644950438 0.149594569 YLVLDEADR ddPTM_HeLa_Curcumin_4h_R1 3 YLVLDEADR 9 0 A0A2R8YCW1;A0A2R8Y4A4;A0A2R8YFS5;A0A2R8Y5G6;A0A2R8YFR4;A0A0D9SFB3;A0A2R8Y645;O00571;O00571-2;A0A2U3TZJ9;A0A0D9SF53;A0A2R8YF78;F6S8Q4;A0A0D9SG12;A0A2R8YDT5;A0A2R8Y7T2;O15523-2;O15523;A0A2R8YDH3;D6RCM4;Q9NQI0-2;Q9NQI0-4;Q9NQI0;Q9NQI0-3 A0A2R8YCW1 DDX3X;DDX3Y;DDX4 ATP-dependent RNA helicase DDX3X;ATP-dependent RNA helicase DDX3Y;Probable ATP-dependent RNA helicase DDX4 0 0 ;; ;; 141.52 0.0032406 20430100 5500.5 4258.3 4607 4369.2 4663.8 8343.5 5241.7 4913.3 5343.2 4899.9 FALSE FALSE TRUE 5065.129621 4626.368477 4777.739473 4351.121408 4608.187231 6612.964049 5388.767995 6411.342552 4757.064328 5070.17116 0.999005647 0.912467909 0.942323113 0.858180379 0.908881986 1.304288128 1.062837491 1.264521916 0.938245313 1 12.30781874 -5.268544854 24.99929575 0.972319868 1.195778012 0.716887722 0.076385221 251.4112441 884545.0372 0.011027699 0.025153154 5.39E-06 5.268544854 0.223458144 YMAENPTAGVVQEEEEDNLEY(ph)DSDGNPIAPTKK ddPTM_HeLa_Curcumin_4h_R1 1 YMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKK 33 1 Q86XP3;J3KRE3;A0A0A0MSJ0;Q86XP3-2 Q86XP3 DDX42 ATP-dependent RNA helicase DDX42 1 0 YMAENPT(0.004)AGVVQEEEEDNLEY(0.698)DS(0.298)DGNPIAPTKK 56.247 0.0081253 120140000 6102.9 5203.1 5788.4 5956 5348.3 7576.8 5257.4 5802.2 6691.2 5746.9 TRUE FALSE FALSE 5619.849025 5652.832779 6002.923196 5931.35565 5284.525016 6005.286272 5404.908494 7571.26407 5957.192101 5946.604347 0.94505178 0.950598434 1.009470758 0.99743573 0.888662623 1.00986814 0.908906693 1.273207973 1.00178047 1 12.53785037 -4.254421828 24.96054901 0.969363247 1.273208117 0.830271845 0.041397547 225.7314831 802878.1277 0.00536976 0.071605873 5.57E-05 4.254421828 0.30384487 YMAENPTAGVVQEEEEDNLEYDS(ph)DGNPIAPTKK ddPTM_HeLa_Curcumin_4h_R1 1 YMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKK 33 1 Q86XP3;J3KRE3;A0A0A0MSJ0;Q86XP3-2 Q86XP3 DDX42 ATP-dependent RNA helicase DDX42 1 0 Y(0.002)MAENPT(0.004)AGVVQEEEEDNLEY(0.479)DS(0.515)DGNPIAPTKK 49.942 0.0033821 34473000 5351.6 3795.8 4731.7 4809 4155.4 5992.2 4703.8 4399.2 5700.8 4994.4 TRUE FALSE FALSE 4928.015213 4123.892038 4907.060964 4789.101632 4105.849569 4749.350174 4835.775968 5740.495829 5075.436503 5167.955028 0.953571613 0.79797367 0.949516963 0.926691816 0.794482449 0.918999904 0.935723307 1.110786723 0.982097653 1 12.3353778 -7.759695354 2.504157035 0.983806011 0.915098308 0.095505225 0.083295512 0.409869624 5.34305999 0.016158985 0.016009832 1.74E-08 7.759695354 -0.068707704 YMEDSTY(ph)YK ddPTM_HeLa_Curcumin_4h_R1 1 YMEDSTYYK 9 0 Q05397-5;Q05397;Q05397-7;Q05397-2;E7ESA6;H0YBP1;H0YB16;H0YBZ1;E9PEI4;Q05397-3;Q05397-4 Q05397-5 PTK2 Focal adhesion kinase 1 1 0 YMEDS(0.044)T(0.044)Y(0.912)YK 149.65 0.010673 52739000 2625.1 2000 2156.8 2986.7 2395 2915.6 2212.8 1210.1 2678 2342.7 TRUE FALSE FALSE 2417.320565 2172.871088 2236.732905 2974.341827 2366.441189 2310.871694 2274.885213 1579.053919 2384.2301 2424.108651 0.99719976 0.896358786 0.92270324 1.22698371 0.976210859 0.953287178 0.938441935 0.651395687 0.98354919 1 11.24323865 -3.993017277 1.583611041 0.999450311 0.290840961 0.597607879 0.084150194 1.114347053 1.520719989 0.011721581 1.4907533 0.000101621 3.993017277 -0.708609349 YMEDVTQIVVEPEPTAEEKPS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 YMEDVTQIVVEPEPTAEEKPSPR 23 1 O15297-2;O15297 O15297-2 PPM1D Protein phosphatase 1D 1 0 YMEDVTQIVVEPEPT(0.031)AEEKPS(0.969)PR 78.942 0.0013645 3217100 675.45 538.28 545.99 667.74 701.08 869.72 520.57 656.57 825.52 711.99 TRUE FALSE FALSE 621.9874198 584.8065247 566.2248697 664.9770688 692.7200789 689.3302682 535.1757932 856.7551705 734.9625213 736.7315995 0.844252398 0.793785043 0.768563301 0.902604245 0.94026112 0.935659973 0.726418948 1.162913565 0.997598748 1 9.524995313 -4.234279553 23.88270795 0.895654916 1.162914247 0.458649701 0.090956938 4095.885342 3601571.764 0.013568213 1.471514645 5.83E-05 4.234279553 0.267259331 YMIGVTYGGDDIPLS(ph)PYR ddPTM_HeLa_Curcumin_4h_R1 1 YMIGVTYGGDDIPLSPYR 18 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 1 0 YMIGVT(0.018)Y(0.007)GGDDIPLS(0.975)PYR 95.073 0.0024454 8017500 1166.2 848.75 1040.2 1287.8 975.95 2640.4 2158.1 1147.3 1530.1 775.12 TRUE FALSE FALSE 1073.894039 922.112168 1078.750727 1282.471425 964.3124337 2092.751277 2218.650478 1497.106488 1362.251858 802.0553623 1.338927573 1.149686432 1.344982875 1.598981174 1.202301585 2.60923544 2.766206152 1.866587469 1.698451157 1 9.647558013 -5.26565911 24.9648686 1.213119269 2.449229367 0.715655599 0.305411308 104.7382486 619656.8437 0.039020829 0.090230737 5.42E-06 5.26565911 1.236110098 TNSPAYS(ph)DISDAGEDGEGKVDSVK ddPTM_HeLa_Curcumin_4h_R1 1 TNSPAYSDISDAGEDGEGKVDSVK 24 1 O15014 O15014 ZNF609 Zinc finger protein 609 1 0 T(0.153)NS(0.206)PAY(0.163)S(0.307)DIS(0.171)DAGEDGEGKVDSVK 47.286 0.015022 5834400 2864.5 1880.5 2343.9 2422.8 2199.6 2835.5 2018.5 897.92 2933.9 2535.1 TRUE FALSE FALSE 2637.771802 2043.042041 2430.766996 2412.775096 2173.371207 2247.385337 2075.133677 1171.691674 2612.05851 2623.194536 1.005557066 0.778837411 0.926643816 0.919785042 0.828520789 0.856736055 0.791071211 0.446665948 0.995754785 1 11.35710909 -3.7445987 0.478367059 0.989606474 1.34E-34 0.743207106 0.08014987 2.452789539 0.265579062 0.017302363 1.522902107 0.000180053 3.7445987 -0.989606474 down YMNSDTTS(ph)PELR ddPTM_HeLa_Curcumin_4h_R1 6 YMNSDTTSPELR 12 0 Q96ST3 Q96ST3 SIN3A Paired amphipathic helix protein Sin3a 1 0 YMNS(0.007)DT(0.001)T(0.032)S(0.96)PELR;YMNS(0.001)DT(0.006)T(0.108)S(0.886)PELR;YMNSDTT(0.004)S(0.996)PELR;YMNSDT(0.001)T(0.032)S(0.966)PELR;YMNSDT(0.003)T(0.028)S(0.968)PELR;YMNSDTT(0.003)S(0.997)PELR ;;;;; 179.83 0.00010337 254265000 17196.2 13961.4 13401.1 15381.1 14874.4 18245.2 14493.7 11464.4 15970.7 14591.7 TRUE FALSE FALSE 15835.10262 15168.16121 13897.75655 15317.45708 14697.03249 14460.93985 14900.35421 14959.84278 14218.75417 15098.76049 1.048768383 1.004596451 0.920456786 1.014484407 0.973393313 0.957756755 0.986859433 0.990799397 0.941716651 1 13.8821425 -6.991682826 24.99990054 1.023221774 0.974533223 0 0.036131145 141.8776395 426455.0964 0.004432774 0.005819539 1.02E-07 6.991682826 -0.048688551 YMS(ph)QMSVPEQAELEK ddPTM_HeLa_Curcumin_4h_R1 2 YMSQMSVPEQAELEK 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 0 Y(0.047)MS(0.68)QMS(0.272)VPEQAELEK;Y(0.054)MS(0.786)QMS(0.159)VPEQAELEK ; 77.146 0.0082238 26872400 7780.3 4843.9 7905.4 8089.3 6892.4 6228.2 6020 8188.2 4982.9 5854.9 TRUE FALSE FALSE 7164.481045 5262.585132 8198.381078 8055.82862 6810.212632 4936.401114 6188.904998 10684.74449 4436.288337 6058.357339 1.182578155 0.868648849 1.353234981 1.329705095 1.12410217 0.81480851 1.021548359 1.763637218 0.732259272 1 12.56471096 -4.257951652 24.79878467 1.088550834 1.763637504 0.526881207 0.200220912 166.0623667 1180692.854 0.023518588 0.230003181 5.52E-05 4.257951652 0.67508667 YMSQMS(ph)VPEQAELEK ddPTM_HeLa_Curcumin_4h_R1 1 YMSQMSVPEQAELEK 15 0 A0A5H1ZRS1;A0A4W8VX11;Q15154-5;Q15154-4;Q15154-2;Q15154;E9PGW9;E7EV93;E5RGQ4;Q15154-3 A0A5H1ZRS1 PCM1 Pericentriolar material 1 protein 1 0 Y(0.009)MS(0.078)QMS(0.913)VPEQAELEK 68.978 0.013459 32625000 3706.3 2613.2 3948.9 4008.6 3032 2350.8 2362.6 3280.8 2665.2 2884.7 TRUE FALSE FALSE 3412.942444 2839.073364 4095.249708 3992.013475 2995.84538 1863.217581 2428.888197 4281.100817 2372.834228 2984.94311 1.143386094 0.951131482 1.371969098 1.337383437 1.003652421 0.624205391 0.813713397 1.434231963 0.79493449 1 11.54348772 -5.526448466 24.98278712 1.104530763 0.921501943 0.0587128 0.249089728 172.1188667 1204577.245 0.033190786 0.066636546 2.98E-06 5.526448466 -0.18302882 YNAPTSHVT(ph)PSVK ddPTM_HeLa_Curcumin_4h_R1 1 YNAPTSHVTPSVK 13 0 O60271-3;O60271;A0A087X2D8;O60271-5;O60271-9;O60271-4;O60271-2 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 YNAPTSHVT(0.983)PS(0.017)VK 110.6 0.0037252 17253000 7808.6 6269.8 6545.2 7952 7948.2 11417 8637.9 2242.7 7807 5074.1 TRUE FALSE FALSE 7190.54107 6811.733574 6787.77087 7919.096731 7853.422906 9048.985504 8880.256226 2926.488906 6950.591632 5250.424597 1.36951611 1.297368136 1.292804181 1.508277394 1.495769106 1.723476899 1.691340588 0.55738138 1.323815151 1 12.35821838 -9.082092841 0.517110016 0.938347625 1.412306797 0.012431962 0.322687306 1.704778919 0.695738012 0.399288011 0.078897411 8.28E-10 9.082092841 0.473959172 YNAPTSHVTPS(ph)VK ddPTM_HeLa_Curcumin_4h_R1 1 YNAPTSHVTPSVK 13 0 O60271-3;O60271;A0A087X2D8;O60271-5;O60271-9;O60271-4;O60271-2 O60271-3 SPAG9 C-Jun-amino-terminal kinase-interacting protein 4 1 0 YNAPTS(0.001)HVT(0.165)PS(0.833)VK 163.99 0.00017401 6356900 1623.1 1197.9 1555.7 1704.9 1692.5 2586.5 2013 465.9 1738.9 1289.3 TRUE FALSE FALSE 1494.629922 1301.441138 1613.355611 1697.845576 1672.318043 2050.030744 2069.479362 607.9507653 1548.147021 1334.103079 1.120325667 0.975517678 1.209318557 1.272649469 1.253514866 1.536635944 1.551213991 0.455699994 1.160440332 1 10.38165442 -6.63081679 5.656458905 1.052609711 1.251622862 0.051947958 0.288116783 0.372022406 17.37252424 0.042614149 0.060485588 2.34E-07 6.63081679 0.199013152 YNDWS(ph)DDDDDSNESK ddPTM_HeLa_Curcumin_4h_R1 2 YNDWSDDDDDSNESK 15 0 Q9UH62;H3BV87 Q9UH62 ARMCX3 Armadillo repeat-containing X-linked protein 3 1 0 YNDWS(0.604)DDDDDS(0.394)NES(0.002)K;YNDWS(0.999)DDDDDSNESK ; 145.82 0.00048417 6522200 2581.9 2471.2 2683 2469.3 2952.4 3254.5 2078.07 2066.89 2786.2 2507.8 TRUE FALSE FALSE 2377.539891 2684.799517 2782.43434 2459.082691 2917.194558 2579.480014 2136.375051 2697.075246 2480.560831 2594.945863 0.916219457 1.034626408 1.072251402 0.947643157 1.124183205 0.994040011 0.823283091 1.039357038 0.95592007 1 11.34148873 -2.737483752 13.15831082 0.978033633 1.144730474 0 0.081926813 0 0 0.010793039 0 0.001830275 2.737483752 0.166696841 YNDWSDDDDDS(ph)NESK ddPTM_HeLa_Curcumin_4h_R1 3 YNDWSDDDDDSNESK 15 0 Q9UH62;H3BV87 Q9UH62 ARMCX3 Armadillo repeat-containing X-linked protein 3 1 0 YNDWS(0.002)DDDDDS(0.73)NES(0.268)K;YNDWS(0.001)DDDDDS(0.996)NES(0.002)K;YNDWS(0.419)DDDDDS(0.58)NES(0.001)K ;; 145.7 0.00048532 558030000 5287.8 5230.1 4954.81 5498.7 5166.5 5090.7 4720.2 3927.6 5880.7 5852.72 TRUE FALSE FALSE 4869.26505 5682.166539 5138.439617 5475.947836 5104.892862 4034.831436 4852.636108 5125.10716 5235.601923 6056.101584 0.804026317 0.938254826 0.848473155 0.904203432 0.842933823 0.666242364 0.8012805 0.846271663 0.86451686 1 12.56417369 -13.52287874 0.206026789 1.847246286 0.793904259 0.155733531 0.077820688 32.96798283 0.405921863 11.26599094 0.066977328 3.00E-14 13.52287874 -1.053342026 YNFFTGCPK ddPTM_HeLa_Curcumin_4h_R1 1 YNFFTGCPK 9 0 Q99832-3;Q99832;Q99832-2;Q99832-4 Q99832-3 CCT7 T-complex protein 1 subunit eta 0 0 113.66 0.0024277 1938700 1069.4 775.64 908.74 860.31 850.45 1076.3 1009 1098.4 1094.1 449.64 FALSE FALSE TRUE 984.7558616 842.6828654 942.4187038 856.7502652 840.3089392 853.0632476 1037.309824 1433.297104 974.0799673 465.2649565 2.116548534 1.811189202 2.025552732 1.841424447 1.806086892 1.833499892 2.229503447 3.080604037 2.093602696 1 8.861908718 -10.29581151 0.267560694 1.81E-31 2.246396486 0.054900791 0.47296174 4.85212373 0.287994829 3.596187968 0.234738045 5.06E-11 10.29581151 2.246396486 YNGLIHR ddPTM_HeLa_Curcumin_4h_R1 3 YNGLIHR 7 0 H0YMF4;H0YKD8;P46779-4;P46779-5;P46779;P46779-2;P46779-3;H0YLP6 H0YMF4 RPL28 60S ribosomal protein L28 0 0 ;; ;; 106.42 0.0075494 14112400 11631.2 8159.8 10502 9176.7 11516.6 11897 9637.8 9845.9 9032.2 9567.5 FALSE FALSE TRUE 10710.57825 8865.096753 10891.21336 9138.729247 11379.27207 9429.428093 9908.210729 12847.86959 8041.390257 9899.969913 1.081879879 0.89546704 1.100125905 0.92310677 1.149424914 0.952470379 1.000832408 1.297768549 0.812264111 1 13.27320843 -4.258176023 24.69464507 1.025978583 1.297768669 0.414914436 0.101912807 146.0096676 1104827.661 0.009617585 0.091653656 5.52E-05 4.258176023 0.271790086 YNILGTNTIMDK ddPTM_HeLa_Curcumin_4h_R1 4 YNILGTNTIMDK 12 0 A0A1W2PPS1;Q00839-2;Q00839;A0A1W2PP35;Q5RI18;A0A1X7SBS1;A0A1W2PQL0;A0A1W2PP34;A0A1W2PPL4;A0A1W2PPH7;A0A1W2PRZ7;A0A1W2PQD4;A0A1W2PQ74 A0A1W2PPS1 HNRNPU Heterogeneous nuclear ribonucleoprotein U 0 0 ;;; ;;; 160.52 1.16E-05 4027900 1634.4 1451.46 1044.43 1385.651 1520.66 1748.63 1510.05 1066.225 1518.58 1332.36 FALSE FALSE TRUE 1505.035515 1576.917735 1083.137495 1379.917543 1502.527123 1385.944427 1552.417939 1391.312094 1351.995573 1378.659411 1.091665935 1.14380515 0.785645451 1.000912577 1.089846492 1.00528413 1.126034412 1.009177527 0.980659591 1 10.42905038 -3.919562804 19.47940084 1.036536727 7.98E-06 0 0.097492018 2043.111459 523983.3436 0.012818907 5458.542008 0.000120348 3.919562804 -1.03652875 YNLDAS(ph)EEEDSNK ddPTM_HeLa_Curcumin_4h_R1 3 YNLDASEEEDSNK 13 0 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 Y(0.025)NLDAS(0.972)EEEDS(0.003)NK;YNLDAS(1)EEEDSNK;Y(0.001)NLDAS(0.998)EEEDSNK ;; 218.2 1.29E-13 70041000 10012.9 9604 10388.6 9106.9 13485.2 10228.8 10331.3 9541.4 7446.8 7858.8 TRUE FALSE FALSE 9220.368399 10434.12697 10773.61065 9069.218061 13324.3978 8107.231578 10621.16847 12450.52894 6629.904671 8131.892715 1.133852686 1.283111734 1.324858927 1.115265336 1.638535857 0.996967356 1.306112715 1.53107393 0.815296623 1 12.98937547 -7.559233554 0.480551705 0.998745301 1.346096454 0.422497521 0.182123274 0.661883113 0.383479419 0.078604253 0.071078122 2.76E-08 7.559233554 0.347351153 YNLDAS(ph)EEEDSNKK ddPTM_HeLa_Curcumin_4h_R1 1 YNLDASEEEDSNKK 14 1 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 YNLDAS(0.993)EEEDS(0.007)NKK 192.4 8.52E-06 103590000 5236.3 5207 5046.7 4979.4 5660.7 4858 4641.2 4666.1 4443.7 3467.9 TRUE FALSE FALSE 4821.84133 5657.069878 5233.735142 4958.796562 5593.19985 3850.396039 4771.419581 6088.77241 3956.237228 3588.409267 1.343726696 1.576484023 1.45851121 1.381892698 1.558685042 1.073009167 1.329675415 1.696788732 1.102504462 1 11.80912873 -8.691070122 0.740221356 1.009419365 1.42332682 0.455772005 0.163098084 0.413946972 0.448255813 0.089643291 0.035741948 2.04E-09 8.691070122 0.413907456 YNLDAS(ph)EEEDSNKKK ddPTM_HeLa_Curcumin_4h_R1 1 YNLDASEEEDSNKKK 15 2 O95218-2;O95218 O95218-2 ZRANB2 Zinc finger Ran-binding domain-containing protein 2 1 0 YNLDAS(0.937)EEEDS(0.063)NKKK 46.15 0.020398 258330000 3883.5 3303.6 4109.4 3854 4337.2 3847.1 3678.9 3180 3645 2861.1 TRUE FALSE FALSE 3576.116877 3589.148463 4261.697979 3838.053169 4285.481723 3049.168094 3782.120033 4149.567361 3245.152619 2960.523012 1.20793416 1.212335945 1.439508479 1.296410517 1.447542108 1.029942372 1.277517526 1.401633206 1.096141664 1 11.53163635 -8.357798748 0.618791715 1.006604728 1.303216289 0.409704907 0.118478083 0.46432616 0.38158038 0.063203679 0.030453062 4.39E-09 8.357798748 0.296611561 YNLTLENNSGSK ddPTM_HeLa_Curcumin_4h_R1 1 YNLTLENNSGSK 12 0 A0A0A0MRA3;A0A0A0MTS7;Q8WZ42-3;Q8WZ42-10;Q8WZ42-9;Q8WZ42-5;Q8WZ42-11;Q8WZ42-4;Q8WZ42-7;Q8WZ42-2;Q8WZ42;Q8WZ42-8;Q8WZ42-13;Q8WZ42-12 A0A0A0MRA3 TTN Titin 0 0 97.472 0.012169 5871100 1773.7 1451.9 1431.8 1911 1746.3 2170.7 1672.6 1282 1940.3 1784.1 FALSE FALSE TRUE 1633.309773 1577.395766 1484.863768 1903.092788 1725.476513 1720.472351 1719.528654 1672.875898 1727.453944 1846.097342 0.884736539 0.854448858 0.804325825 1.030873478 0.934661718 0.931951047 0.931439862 0.906168846 0.935732859 1 10.85026291 -9.343184423 1.12041253 0.998926035 0.909263524 0.100181489 0.058874238 0.545354956 1.247018305 0.037035431 0.010180735 4.54E-10 9.343184423 -0.089662511 YNTEGRVS(ph)PSPSQESLSSSK ddPTM_HeLa_Curcumin_4h_R1 2 YNTEGRVSPSPSQESLSSSK 20 1 Q5JSH3-2;Q5JSH3;Q5JSH3-4;H7BY83;Q5JSH3-3 Q5JSH3-2 WDR44 WD repeat-containing protein 44 1 0 Y(0.01)NT(0.052)EGRVS(0.777)PS(0.135)PS(0.025)QES(0.001)LSSSK;Y(0.022)NT(0.085)EGRVS(0.617)PS(0.238)PS(0.038)QES(0.001)LSSSK ; 63.138 0.0054517 72490000 3522.4 2870.2 3264.3 2967.1 2766.04 3200.8 2794 5055.8 3675.4 3013.6 TRUE FALSE FALSE 3243.598323 3118.287299 3385.27783 2954.822926 2733.05678 2536.918 2872.39212 6597.290146 3272.217815 3118.322376 1.040174149 0.999988751 1.085608677 0.947568138 0.876451005 0.813552191 0.921133794 2.11565366 1.049351998 1 11.60655437 -4.259322414 24.99878539 0.989653511 2.115654046 0.947034846 0.081135786 32.91850907 388699.5651 0.012378472 0.10951648 5.50E-05 4.259322414 1.126000535 YPDVAS(ph)PTLR ddPTM_HeLa_Curcumin_4h_R1 1 YPDVASPTLR 10 0 A0A0A0MTE8;Q8IVL1-8;Q8IVL1-9;Q8IVL1-10;Q8IVL1-13;Q8IVL1-12;Q8IVL1-11;Q8IVL1;A0A0A0MTL4;Q8IVL1-4;Q8IVL1-3;Q8IVL1-2;Q8IVL1-5;E9PNV5 A0A0A0MTE8 NAV2 Neuron navigator 2 1 0 YPDVAS(0.705)PT(0.295)LR 114.76 0.0055556 34328000 3003.2 2415.7 2695.3 2286.2 3049.4 3179.2 2793.3 532.03 2688.1 2393.4 TRUE FALSE FALSE 2765.493551 2624.502344 2795.190189 2276.74031 3013.037897 2519.798083 2871.67248 694.2434978 2393.222155 2476.570472 1.116662571 1.059732551 1.128653604 0.91931174 1.216617064 1.017454626 1.159535944 0.280324548 0.966345268 1 11.27412796 -4.257271299 24.99984504 1.065760211 0.280324241 0.879199172 0.087248492 90.28713796 541514.8304 0.010672358 0.110853334 5.53E-05 4.257271299 -0.78543597 LTPVRPAAAS(ph)PIVSGAR ddPTM_HeLa_Curcumin_4h_R1 2 LTPVRPAAASPIVSGAR 17 1 I3VM54;Q9Y2K7-3;Q9Y2K7;Q9Y2K7-4;Q9Y2K7-5;Q9Y2K7-2 I3VM54 KDM2A Lysine-specific demethylase 2A 1 0 LTPVRPAAAS(0.984)PIVS(0.016)GAR;LTPVRPAAAS(0.973)PIVS(0.027)GAR ; 91.889 0.0016231 221690000 3438.1 2773.2 2807.4 3366.6 2854.1 3188.2 2418.97 1278.39 3248.6 3369.1 TRUE FALSE FALSE 3165.970757 3012.903051 2911.444714 3352.669901 2820.066722 2526.931382 2486.839788 1668.165226 2892.236708 3486.175974 0.908150013 0.864242962 0.835139917 0.96170415 0.808928391 0.724843324 0.713343161 0.478508612 0.829630153 1 11.76742968 -3.71716409 0.401686372 0.963010233 1.08E-19 0.77440414 0.067024406 1.987956884 0.158796926 0.014491862 1.006366281 0.000191794 3.71716409 -0.963010233 down AALGVLGPEVEKEAVS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 AALGVLGPEVEKEAVSPR 18 1 O95382-3;O95382 O95382-3 MAP3K6 Mitogen-activated protein kinase kinase kinase 6 1 0 AALGVLGPEVEKEAVS(1)PR 89.663 0.0013024 3829900 3007.1 2451 2445.9 3176.8 2233.2 2928.1 2095.8 1058.7 3486.2 3212.2 TRUE FALSE FALSE 2769.084862 2662.853519 2536.547206 3163.655243 2206.570549 2320.779054 2154.602507 1381.492756 3103.772582 3323.823711 0.833102205 0.801141622 0.763141317 0.951811985 0.663865096 0.698225675 0.648230079 0.415633582 0.933795788 1 11.69862815 -3.690795465 0.238375856 0.979243885 1.50E-20 0.770394656 0.079403076 5.103224929 0.188404183 0.06035756 1.541009989 0.0002038 3.690795465 -0.979243885 down YPGGS(ph)PIPADPR ddPTM_HeLa_Curcumin_4h_R1 1 YPGGSPIPADPR 12 0 Q9BY89 Q9BY89 KIAA1671 Uncharacterized protein KIAA1671 1 0 Y(0.001)PGGS(0.999)PIPADPR 84.605 0.020282 23493000 1656.5 1284.1 1366.6 1533.6 1546.3 1737.2 1508.3 610.97 1524.6 1224.7 TRUE FALSE FALSE 1525.386277 1395.091882 1417.247398 1527.25437 1527.861382 1376.885138 1550.618839 797.2519404 1357.355194 1267.258234 1.203690169 1.10087419 1.118357222 1.20516429 1.205643287 1.086507155 1.223601313 0.629115613 1.071095976 1 10.30749482 -4.253989568 24.96522431 1.12005686 0.629115376 0.818605929 0.071127758 356.6868381 1195271.691 0.012409029 0.174492484 5.57E-05 4.253989568 -0.490941484 YPIEHGIITNWDDMEK ddPTM_HeLa_Curcumin_4h_R1 7 YPIEHGIITNWDDMEK 16 0 P68133;P68032;P63267;P62736;A6NL76;F8WB63;B8ZZJ2;C9JFL5;F6UVQ4;F6QUT6 P68133 ACTA1;ACTC1;ACTG2;ACTA2 "Actin, alpha skeletal muscle;Actin, alpha cardiac muscle 1;Actin, gamma-enteric smooth muscle;Actin, aortic smooth muscle" 0 0 ;;;;;; ;;;;;; 176.87 2.63E-06 2058840900 21184.5 18899.3 25722.1 18943.4 18061 40346.3 28153 22961.09 13692.7 9395.19 FALSE FALSE TRUE 19507.72447 20532.87128 26675.38365 18865.01723 17845.63437 31978.02258 28942.89741 29961.82064 12190.64507 9721.672153 2.006622334 2.112071972 2.743908994 1.940511564 1.835654823 3.289354144 2.977152177 3.081961639 1.253965869 1 13.24698877 -5.967488016 0.118649045 2.68E-17 4.873600644 0.748520852 0.369827681 6.234226574 0.264466616 3.533602106 7.237494653 1.08E-06 5.967488016 4.873600644 up YPSSISSS(ph)PQK ddPTM_HeLa_Curcumin_4h_R1 2 YPSSISSSPQK 11 0 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 0 YPSSISS(0.077)S(0.923)PQK;YPSS(0.01)IS(0.06)S(0.354)S(0.576)PQK ; 152.69 0.00048509 63213000 6687.4 5701.7 6944.9 5879.5 8006.6 7211.2 6931.9 4260.9 5625.4 5309.4 TRUE FALSE FALSE 6158.085233 6194.529542 7202.284103 5855.172187 7911.126524 5715.515833 7126.390458 5560.028795 5008.307694 5493.901255 1.120894779 1.127528373 1.310959875 1.065758541 1.439983385 1.040338289 1.297145713 1.012036536 0.911612252 1 12.42361526 -8.087807155 0.687753582 1.012896349 1.196112891 0.29517756 0.132068731 0.593736758 0.6234317 0.045911906 0.02964171 8.17E-09 8.087807155 0.183216542 YPSSISSS(ph)PQKDLTQAK ddPTM_HeLa_Curcumin_4h_R1 2 YPSSISSSPQKDLTQAK 17 1 F8W726;Q14157-4;Q14157-1;Q14157-3;Q14157;Q14157-5 F8W726 UBAP2L Ubiquitin-associated protein 2-like 1 0 Y(0.019)PS(0.009)S(0.012)IS(0.283)S(0.05)S(0.626)PQKDLTQAK;YPS(0.004)S(0.01)IS(0.095)S(0.077)S(0.813)PQKDLTQAK ; 72.383 0.0074012 667490000 4000.3 3613.1 3643 3924.6 4593.6 4641.7 4363 2730.1 4679.2 3257.7 TRUE FALSE FALSE 3683.672034 3925.400264 3778.012785 3908.361045 4538.82432 3678.959097 4485.414038 3562.494922 4165.903467 3370.904833 1.092784346 1.164494538 1.12077112 1.159439747 1.34647062 1.091386224 1.330626126 1.056836398 1.235841317 1 11.71892018 -7.548804187 0.554402742 1.00936236 1.208069893 0 0.11241902 0.470917263 0.340820128 0.031275061 0.02925982 2.83E-08 7.548804187 0.198707534 YPVNSVNILK ddPTM_HeLa_Curcumin_4h_R1 1 YPVNSVNILK 10 0 P17987;E7EQR6;E7ERF2 P17987 TCP1 T-complex protein 1 subunit alpha 0 0 114.4 0.0040332 1986400 920.32 725.9 692.23 828.66 694.15 828.23 765.63 804.2 934.24 899.29 FALSE FALSE TRUE 847.4757009 788.6435615 717.8846527 825.2312245 685.8727146 656.4457619 787.1115172 1049.396878 831.7562094 930.5402606 0.910735125 0.847511489 0.771470815 0.886830221 0.73706936 0.705445847 0.845865086 1.127728614 0.89384226 1 9.861924761 -7.856690497 0.950340557 0.981110421 0.834765026 0.089372434 0.113437444 0.509066635 0.978364846 0.029908475 0.025519367 1.39E-08 7.856690497 -0.146345396 YQAVTATLEEK ddPTM_HeLa_Curcumin_4h_R1 2 YQAVTATLEEK 11 0 Q8J015;M0QYS1;P40429;Q6NVV1 Q8J015 RPL13a;RPL13A;RPL13AP3 60S ribosomal protein L13a;Putative 60S ribosomal protein L13a protein RPL13AP3 0 0 ; ; 240.37 1.26E-51 10675400 5668.3 5116.6 5436.7 5098.2 4747.8 6277 4642.7 4317.5 5692.3 4816.9 FALSE FALSE TRUE 5219.648074 5558.856105 5638.188885 5077.104999 4691.185586 4975.079444 4772.961667 5633.885875 5067.868931 4984.286916 1.047220628 1.115276106 1.131192682 1.018622139 0.941194932 0.9981527 0.957601708 1.130329367 1.016769102 1 12.2831714 -6.002501373 24.99299822 1.040314534 0.999837976 0.105919433 0.06193478 217.125328 2169491.685 0.00964797 0.017264482 9.94E-07 6.002501373 -0.040476558 YQDEVFGGFVTEPQEES(ph)EEEVEEPEER ddPTM_HeLa_Curcumin_4h_R1 9 YQDEVFGGFVTEPQEESEEEVEEPEER 27 0 Q13283 Q13283 G3BP1 Ras GTPase-activating protein-binding protein 1 1 0 YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER;YQDEVFGGFVTEPQEES(1)EEEVEEPEER ;;;;;;;; 187.72 3.11E-16 1366359800 37493.5 34274.1 36273.6 35896.4 39601.8 44204 36937.8 39120.7 36052.9 33086.2 TRUE FALSE FALSE 34525.84991 37236.60048 37617.93153 35747.87021 39129.5744 35035.59212 37974.17525 51048.42134 32097.98707 34235.94299 1.008467911 1.08764641 1.098784734 1.044161986 1.142938415 1.023357006 1.109190282 1.49107683 0.937552299 1 15.06322413 -1.618848505 1.103443121 1.026454883 199.999999 0.843118049 0.057187052 173.3824122 0.640885848 0.008382931 86783.8559 0.024052017 1.618848505 198.9735441 YQEDS(ph)DPERS(ph)DYEEQQLQK ddPTM_HeLa_Curcumin_4h_R1 1 YQEDSDPERSDYEEQQLQK 19 1 Q6P6C2-3;Q6P6C2;Q6P6C2-1 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 2 0 Y(0.008)QEDS(0.992)DPERS(0.848)DY(0.152)EEQQLQK 89.468 0.0015529 9283800 8697.1 7720.7 9231.4 7910.6 9862.5 9556.7 9153.6 6255.9 7267.1 6960.1 TRUE FALSE FALSE 8008.715358 8388.042905 9573.523805 7877.868033 9744.896129 7574.532694 9410.42538 8163.295111 6469.917311 7201.962957 1.112018405 1.164688427 1.329293675 1.093850118 1.353088899 1.051731693 1.30664729 1.133481963 0.898354706 1 12.81417446 -7.850323124 0.812475146 1.019689141 1.211529365 0.455264919 0.103899739 0.351090972 0.5025997 0.026182185 0.021495941 1.41E-08 7.850323124 0.191840224 YQEDSDPERS(ph)DYEEQQLQKEEEAR ddPTM_HeLa_Curcumin_4h_R1 1 YQEDSDPERSDYEEQQLQKEEEAR 24 2 Q6P6C2-3;Q6P6C2;Q6P6C2-1 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 0 Y(0.002)QEDS(0.062)DPERS(0.781)DY(0.155)EEQQLQKEEEAR 67.668 0.00035944 38813000 2774.3 2547.2 2525.5 2609.7 2707 2609.1 2686.7 2566.6 2703.7 2557.5 TRUE FALSE FALSE 2554.711228 2767.368618 2619.097252 2598.901753 2674.720793 2067.943249 2762.081571 3349.144525 2407.110874 2646.372935 0.965363269 1.045721327 0.989693182 0.982061794 1.010711967 0.781425483 1.043723481 1.2655603 0.909588684 1 11.36980067 -4.311953858 4.023728012 0.977515805 1.27852377 0.616651387 0.071192238 0.095989516 2.918250089 0.008870565 0.074133554 4.88E-05 4.311953858 0.301007965 YQEDSDPERSDY(ph)EEQQLQKEEEAR ddPTM_HeLa_Curcumin_4h_R1 1 YQEDSDPERSDYEEQQLQKEEEAR 24 2 Q6P6C2-3;Q6P6C2;Q6P6C2-1 Q6P6C2-3 ALKBH5 RNA demethylase ALKBH5 1 0 YQEDSDPERS(0.019)DY(0.98)EEQQLQKEEEAR 107.92 3.38E-06 35530000 1515.8 1366.9 1507.7 1427.9 1658.3 1587.4 1382.9 1645.4 1522.5 1309.6 TRUE FALSE FALSE 1395.822831 1485.048745 1563.576688 1421.991728 1638.525856 1258.155346 1421.700452 2147.074886 1355.485559 1355.108503 1.030045069 1.09588918 1.153838741 1.049356362 1.209147351 0.928453584 1.049141415 1.584430237 1.000278248 1 10.40419266 -4.261909908 7.284849191 1.040349786 1.591143006 0.80382654 0.077719526 0.031805813 14.69075166 0.010762795 0.086253305 5.47E-05 4.261909908 0.55079322 YQEQGGEAS(ph)PQR ddPTM_HeLa_Curcumin_4h_R1 2 YQEQGGEASPQR 12 0 H0Y5J4;Q9UJU6-5;Q9UJU6 H0Y5J4 DBNL Drebrin-like protein 1 0 YQEQGGEAS(1)PQR;YQEQGGEAS(1)PQR ; 177.21 0.0001327 135673000 4868.8 4434.3 4198.7 4865.4 5262.4 6662.5 5500.7 2530.5 4120.5 4285.7 TRUE FALSE FALSE 4483.429342 4817.581133 4354.307516 4845.268264 5199.649317 5280.622398 5655.034838 3302.037801 3668.491459 4434.627756 1.011004664 1.086355247 0.981887941 1.092598642 1.172510885 1.190770159 1.275199441 0.744603151 0.827237744 1 12.11459729 -6.134744223 5.002426569 1.011260442 1.117152911 0.10873882 0.145899635 0.35474947 13.05626304 0.018623342 0.031333909 7.33E-07 6.134744223 0.105892469 YQEQGGEAS(ph)PQSR ddPTM_HeLa_Curcumin_4h_R1 1 YQEQGGEASPQSR 13 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3 B4DDD6 DBNL Drebrin-like protein 1 0 YQEQGGEAS(0.897)PQS(0.103)R 166.79 0.00018325 34656000 1945.1 1663.3 1614.9 1718.8 1734.5 2509.6 2003.1 1221.3 1913.5 1553 TRUE FALSE FALSE 1791.143283 1807.06824 1674.749615 1711.688061 1713.81722 1989.080671 2059.301595 1593.668748 1703.593837 1606.966634 1.11461137 1.12452132 1.042180702 1.065167144 1.0664921 1.237785918 1.281483729 0.991724852 1.060130186 1 10.65012426 -13.52287874 0.127840623 0.57353091 1.182118359 0.13984029 0.083831799 87.77240003 0.798999778 9.573404204 0.321389194 3.00E-14 13.52287874 0.608587449 YQEQGGEASPQR ddPTM_HeLa_Curcumin_4h_R1 2 YQEQGGEASPQR 12 0 H0Y5J4;Q9UJU6-5;Q9UJU6 H0Y5J4 DBNL Drebrin-like protein 0 0 ; ; 128.01 0.00052295 614220 0 0 0 0 200.96 158.07 0 0 163.81 80.224 FALSE FALSE TRUE 0 0 0 0 198.5636833 125.2845002 0 0 145.8404528 83.01177803 0 0 0 0 2.3919941 1.509237643 0 0 1.756864584 1 6.375244141 -4.609916605 24.91636519 0.596638273 4.05E-08 0.08677552 0.835995873 39.33861133 11250.89345 0.114757446 0.429383175 2.46E-05 4.609916605 -0.596638233 YQEQGGEASPQS(ph)R ddPTM_HeLa_Curcumin_4h_R1 1 YQEQGGEASPQSR 13 0 B4DDD6;Q9UJU6-4;Q9UJU6-6;Q9UJU6-2;Q9UJU6-3 B4DDD6 DBNL Drebrin-like protein 1 0 YQEQGGEAS(0.306)PQS(0.694)R 134.02 0.0013831 32778000 2145.2 2220.3 1857.4 2272.6 1830.5 3102.4 2500.6 1414.4 2254.5 1756.7 TRUE FALSE FALSE 1975.405156 2412.212839 1926.236878 2263.196583 1808.672483 2458.927269 2570.760106 1845.644049 2007.18699 1817.745194 1.086733808 1.32703574 1.059684759 1.245057113 0.99500881 1.352734848 1.414257683 1.015348056 1.104218015 1 10.82793427 -7.697807712 0.432574565 0.98940611 1.233063256 0.11449145 0.142469222 0.924855091 0.455250941 0.083370636 0.065159159 2.01E-08 7.697807712 0.243657147 YQLDKDGVVLFK ddPTM_HeLa_Curcumin_4h_R1 1 YQLDKDGVVLFK 12 1 P07237;H7BZ94;I3L398;I3L312;I3L3U6 P07237 P4HB Protein disulfide-isomerase 0 0 121.21 0.00048173 1201100 1484 1365.3 1514 980.99 1215.1 1729.4 1527.2 797.62 914 633.06 FALSE FALSE TRUE 1366.539834 1483.310448 1570.110172 976.9309233 1200.610726 1370.702946 1570.049122 1040.810666 813.7364867 655.0587879 2.086133122 2.264392869 2.396899638 1.491363739 1.832828974 2.092488447 2.396806441 1.588881312 1.242234288 1 9.355480576 -9.144115548 0.831645656 0.978580572 2.030944339 0.580096652 0.302011468 0.330887142 0.40164452 0.219079125 0.058785051 7.18E-10 9.144115548 1.052363768 YQPLASTAS(ph)DNDFVTPEPR ddPTM_HeLa_Curcumin_4h_R1 2 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 0 YQPLAST(0.013)AS(0.987)DNDFVTPEPR;YQPLAST(0.173)AS(0.827)DNDFVTPEPR ; 200.94 2.87E-13 122410000 7445.9 6009 6358.8 6927 6739.5 6909.3 5257.9 3412 7131 6680.4 TRUE FALSE FALSE 6856.549158 6528.391184 6594.462722 6898.337909 6659.135864 5476.233296 5405.422523 4452.303093 6348.747141 6912.543403 0.991899618 0.944426791 0.953985001 0.997944969 0.963340912 0.792216841 0.781973032 0.644090436 0.918438666 1 12.75500092 -4.798138487 0.969686324 0.991758301 0.610216245 0.8835412 0.038654834 0.169359237 0.200936835 0.00480168 0.055298279 1.59E-05 4.798138487 -0.381542056 YQPLASTASDNDFVT(ph)PEPR ddPTM_HeLa_Curcumin_4h_R1 3 YQPLASTASDNDFVTPEPR 19 0 Q15021 Q15021 NCAPD2 Condensin complex subunit 1 1 0 YQPLASTAS(0.046)DNDFVT(0.954)PEPR;YQPLAS(0.001)T(0.009)AS(0.044)DNDFVT(0.946)PEPR;YQPLASTAS(0.013)DNDFVT(0.987)PEPR ;; 200.73 8.46E-13 84203700 7330.4 6298.9 6469.4 6699.9 6311.1 10801.5 9572 2470.72 7616.3 6270.9 TRUE FALSE FALSE 6750.191105 6843.348849 6709.161655 6672.177589 6235.844254 8561.147142 9840.564558 3224.031154 6780.810945 6488.813308 1.040281294 1.054637963 1.033958189 1.028258523 0.961014589 1.319370235 1.516543024 0.496859904 1.04500016 1 12.66373894 -5.302442172 24.98440974 1.020683188 1.151486653 0.018333384 0.244200196 1074.98379 655022.9428 0.03144115 0.070305147 4.98E-06 5.302442172 0.130803465 MGS(ph)KSPGNTSQPPAFFSK ddPTM_HeLa_Curcumin_4h_R1 1 MGSKSPGNTSQPPAFFSK 18 1 Q9Y618;A0A384DVL6;C9J0Q5;Q9Y618-4;C9J7T7;C9JE98;Q9Y618-5;Q9Y618-2;H7C184 Q9Y618 NCOR2 Nuclear receptor corepressor 2 1 0 MGS(0.481)KS(0.421)PGNT(0.072)S(0.026)QPPAFFSK 55.208 0.016327 128590000 4917.2 3693.1 3904.6 4140 3750.2 4604.7 3632.7 1581.7 4420 4322.2 TRUE FALSE FALSE 4527.998431 4012.315108 4049.307911 4122.869777 3705.481314 3649.633314 3734.623785 2063.953049 3935.137058 4472.396128 1.01243233 0.897128741 0.905400102 0.921848078 0.82852261 0.816035344 0.835038686 0.461487084 0.879872208 1 12.12683226 -3.67490193 0.442518064 1.001983557 1.31E-21 0.733646421 0.075264275 2.148652954 0.195277674 0.01441422 1.263160424 0.000211397 3.67490193 -1.001983557 down YQT(ph)QPVTLGEVEQVQSGK ddPTM_HeLa_Curcumin_4h_R1 1 YQTQPVTLGEVEQVQSGK 18 0 O95425-3;A0A6I8PIX7;O95425-2;O95425;O95425-4 O95425-3 SVIL Supervillin 1 0 YQT(0.654)QPVT(0.346)LGEVEQVQSGK 211.13 2.46E-12 4327800 2326.9 1307 2261.7 2505.9 2244.4 3595.2 2967.1 2165.8 2060.9 3606.2 TRUE FALSE FALSE 2142.72341 1419.971256 2345.520592 2495.53125 2217.636996 2849.514994 3050.34884 2826.14245 1834.824426 3731.515182 0.57422342 0.380534766 0.628570561 0.668771566 0.594299336 0.763634839 0.81745583 0.757371285 0.491710294 1 11.86554584 -9.273815379 1.049756474 0.996030395 0.644812394 0 0.193606799 0.328750946 0.660147021 0.082946936 0.023525656 5.32E-10 9.273815379 -0.351218001 YREPPPT(ph)PPGYLGISLADLK ddPTM_HeLa_Curcumin_4h_R1 1 YREPPPTPPGYLGISLADLK 20 1 E9PCH4;Q8TEU7;Q8TEU7-4;A0A5F9ZHG7 E9PCH4 RAPGEF6 Rap guanine nucleotide exchange factor 6 1 0 Y(0.053)REPPPT(0.943)PPGY(0.003)LGIS(0.001)LADLK 77.357 0.0027906 16311000 1537.6 1192.6 1362.5 1549.3 1306.2 2679.6 1518.7 1820.8 1904.3 1408.8 TRUE FALSE FALSE 1415.897338 1295.68303 1412.995449 1542.889407 1290.624418 2123.820755 1561.310635 2375.953538 1695.403054 1457.755695 0.971285753 0.88882042 0.969295097 1.058400535 0.885350284 1.456911307 1.071037239 1.629870867 1.163022762 1 10.50953324 -1 0.564463865 0.97436891 31.26783441 0.588118753 0.150254469 53.66864744 0.429013181 0.022317173 1989.728058 0.1 1 30.2934655 YRNEGS(ph)PSPR ddPTM_HeLa_Curcumin_4h_R1 1 YRNEGSPSPR 10 1 Q5T200-2;Q5T200 Q5T200-2 ZC3H13 Zinc finger CCCH domain-containing protein 13 1 0 YRNEGS(0.88)PS(0.12)PR 68.809 0.019976 3036100 575.44 319.7 525.49 447.8 507.82 546.43 332.6 379.79 368.64 381.54 TRUE FALSE FALSE 529.8933168 347.3334434 544.9651217 445.9471223 501.7645782 433.0942585 341.9318609 495.5862227 328.2011143 394.7984866 1.342186799 0.879773999 1.380362742 1.129556311 1.270938454 1.097000807 0.866092127 1.255289064 0.831313 1 8.624972649 -5.003303348 24.89706447 1.164794248 1.040904586 0 0.196613765 270.6317924 2039803.887 0.024459975 0.071309673 9.92E-06 5.003303348 -0.123889661 YRS(ph)DSQDEVEK ddPTM_HeLa_Curcumin_4h_R1 1 YRSDSQDEVEK 11 1 H7C5V5;H0YF01;H0YBZ4;Q15390-2;Q15390 H7C5V5 MTFR1 Mitochondrial fission regulator 1 1 0 Y(0.306)RS(0.564)DS(0.13)QDEVEK 121.42 0.001755 50292000 4308.8 3783.2 4079.8 4204.7 4078.2 5645.5 3357.4 1597.6 5034.7 3849.5 TRUE FALSE FALSE 3967.753933 4110.20295 4231.000977 4187.302065 4029.570129 4474.559662 3451.599608 2084.700886 4482.406006 3983.269838 0.996104732 1.031866561 1.062192909 1.051222296 1.011623689 1.123338323 0.866524174 0.523364213 1.125308148 1 11.9597375 -4.342015537 2.961138025 1.016409389 0.482570829 0.893425854 0.054550952 0.059908964 0.806432628 0.006121049 0.067864065 4.55E-05 4.342015537 -0.533838561 YRS(ph)PYSGPK ddPTM_HeLa_Curcumin_4h_R1 3 YRSPYSGPK 9 1 G3XAC6;Q14498-2;Q14498;Q5QP22;Q5QP23 G3XAC6 RBM39 RNA-binding protein 39 1 0 YRS(0.999)PYSGPK;YRS(1)PYSGPK;YRS(1)PYSGPK ;; 100.09 0.0057179 2673660000 19176.9 16628.3 18112 19047.1 18410.7 21151.6 18406.3 12184.7 20936.1 17723.9 TRUE FALSE FALSE 17659.02813 18065.57616 18783.24665 18968.28815 18191.16443 16764.51973 18922.73124 15899.75894 18639.46221 18339.80421 0.962879861 0.985047384 1.024179236 1.034268847 0.991895236 0.914105709 1.031784801 0.866953581 1.016339215 1 14.16269062 -4.24775402 24.80551122 0.987086292 0.866953492 0.531364921 0.035442821 1354.719022 2455462.56 0.004727924 0.129392139 5.65E-05 4.24775402 -0.1201328 GHYEVTGSDDETGKLQGS(ph)GVSLASKK ddPTM_HeLa_Curcumin_4h_R1 1 GHYEVTGSDDETGKLQGSGVSLASKK 26 2 Q09666 Q09666 AHNAK Neuroblast differentiation-associated protein AHNAK 1 0 GHY(0.001)EVT(0.009)GS(0.082)DDET(0.232)GKLQGS(0.611)GVS(0.044)LAS(0.022)KK 55.988 0.0018634 208210000 2510.5 2233.9 2431.6 2620 1839.8 3040.3 1712.4 1006.8 3463.5 2756.2 TRUE FALSE FALSE 2311.791276 2426.988362 2521.717235 2609.159134 1817.861587 2409.707509 1760.445335 1313.768685 3083.562715 2851.977745 0.810592327 0.850984327 0.884199479 0.91485957 0.637403847 0.844925075 0.617271765 0.460651801 1.081201535 1 11.47774701 -3.643540133 0.353076354 0.930624939 8.70E-38 0.713813124 0.095402091 4.061855568 0.25487554 0.028928361 1.756854527 0.000227227 3.643540133 -0.930624939 down YS(ph)GAYGASVSDEELKR ddPTM_HeLa_Curcumin_4h_R1 3 YSGAYGASVSDEELKR 16 1 A0A286YEX5;C9JRZ6;F8WAR4;Q9NX63 A0A286YEX5 CHCHD3 MICOS complex subunit MIC19 1 0 Y(0.013)S(0.887)GAY(0.097)GAS(0.003)VSDEELKR;YS(1)GAYGASVSDEELKR;Y(0.058)S(0.941)GAY(0.001)GASVSDEELKR ;; 180.32 7.36E-06 27933600 6315.6 5571.3 6653.6 6788.8 7499.5 7716.6 5634.1 3765.17 6410.8 6317.6 TRUE FALSE FALSE 5815.713596 6052.858347 6900.188269 6760.709744 7410.073361 6116.090176 5792.177683 4913.153 5707.551279 6537.13613 0.889642418 0.925918969 1.055536879 1.034200544 1.133535116 0.93559168 0.886042078 0.751575752 0.873096592 1 12.67444302 -4.413395014 2.151463294 0.971768519 0.730321414 0.469444915 0.075766187 0.369151143 2.401311873 0.011631179 0.150323404 3.86E-05 4.413395014 -0.241447104 S(ph)LSDSESDDSK ddPTM_HeLa_Curcumin_4h_R1 1 SLSDSESDDSK 11 0 Q13185;S4R2Y4 Q13185 CBX3 Chromobox protein homolog 3 1 0 S(0.981)LS(0.018)DSESDDSK 107.97 0.0074638 95964000 1377.6 1173.4 1436.4 1451.5 1544.8 2065.2 1633.3 2130.7 1523.2 1100.4 TRUE FALSE FALSE 1268.561506 1274.823467 1489.634248 1445.494078 1526.379269 1636.85424 1679.126002 2780.340621 1356.108771 1138.638818 1.114103512 1.119603027 1.308258795 1.26949306 1.340529802 1.43755352 1.47467834 2.441810851 1.190991164 1 10.15309447 -1 0.529124112 1.074840966 49.83374669 0.899771791 0.121637799 21.45555758 0.190437426 0.022719928 1184.787617 0.1 1 48.75890573 up YS(ph)HFAQDLWSEQS(ph)IK ddPTM_HeLa_Curcumin_4h_R1 1 YSHFAQDLWSEQSIK 15 0 K7ERD0 K7ERD0 ZNF506 2 0 Y(0.012)S(0.987)HFAQDLWSEQS(1)IK 101.01 0.0086304 19095000 1468.5 1883.1 1482.1 942.12 2261.3 5609.2 2343.5 1656 2205.6 2106.3 TRUE FALSE FALSE 1352.266675 2045.866773 1537.02793 938.2217571 2234.335474 4445.788691 2409.252303 2160.906777 1963.651198 2179.493768 0.620449893 0.938688976 0.705222448 0.430476917 1.025162589 2.039826292 1.105418303 0.991471877 0.90096665 1 11.08977736 -5.515630477 24.89006516 0.789816265 1.381713068 0.453280743 0.300898744 220.7862841 758163.8423 0.044158396 0.09133042 3.05E-06 5.515630477 0.591896803 YS(ph)PDELR ddPTM_HeLa_Curcumin_4h_R1 1 YSPDELR 7 0 S5FZ81;Q8WUB8-3;Q8WUB8-2;Q8WUB8 S5FZ81 PHF10 PHD finger protein 10 1 0 Y(0.001)S(0.999)PDELR 106.6 0.016964 2756700 1789.1 1952.7 1584.9 2111.4 1298.9 1828 1386.7 1157.1 2498.7 2072.8 TRUE FALSE FALSE 1647.490847 2121.482687 1643.637788 2102.663586 1283.411466 1448.852194 1425.60707 1509.894463 2224.598861 2144.829646 0.768122005 0.989114772 0.766325564 0.980340602 0.598374546 0.675509217 0.664671468 0.703969411 1.037191399 1 11.06664735 -5.75759354 24.99999847 0.89143707 0.661982454 0.646439554 0.093452475 56.77220151 369044.0952 0.014499758 0.028146059 1.75E-06 5.75759354 -0.229454616 YS(ph)PPAISPLVSEK ddPTM_HeLa_Curcumin_4h_R1 1 YSPPAISPLVSEK 13 0 Q14694;Q14694-3;Q14694-2 Q14694 USP10 Ubiquitin carboxyl-terminal hydrolase 10 1 0 Y(0.165)S(0.835)PPAISPLVSEK 87.863 0.014513 36876000 2704.4 2362.3 2623.8 2174.1 2619 3438 3318.4 2989.3 2346.9 2142.9 TRUE FALSE FALSE 2490.343886 2566.486686 2721.040336 2165.10415 2587.770136 2724.920046 3411.505373 3900.723809 2089.450942 2217.365615 1.123109274 1.157448581 1.227150055 0.976430831 1.167047111 1.228899748 1.538539855 1.759170333 0.942312322 1 11.11463096 -4.598038018 1.275739017 1.076152433 1.875743083 0.881345069 0.083854358 0.186501445 0.385035812 0.012234088 0.165368417 2.52E-05 4.598038018 0.799590649 YS(ph)PS(ph)QNSPIHHIPSR ddPTM_HeLa_Curcumin_4h_R1 1 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 2 0 Y(0.287)S(0.865)PS(0.837)QNS(0.012)PIHHIPSR 89.846 0.0033776 17496000 2737.8 2650.7 2311.8 2108.8 3534.2 3337 2982.3 1903.2 2122.4 2068.3 TRUE FALSE FALSE 2521.100241 2879.814697 2397.477342 2100.074344 3492.056973 2644.868584 3065.975312 2483.476919 1889.57803 2140.173271 1.177988846 1.345598852 1.120225813 0.981263701 1.631670211 1.235819838 1.432582751 1.160409277 0.882908901 1 11.06351189 -8.295296809 0.246603053 0.904194844 1.362041224 0.361659266 0.17128841 2.718258866 0.427778757 0.452214581 0.207643253 5.07E-09 8.295296809 0.457846381 YSCPESPSQELGGPLPS(ph)PGPR ddPTM_HeLa_Curcumin_4h_R1 1 YSCPESPSQELGGPLPSPGPR 21 0 A0A494BZV2;A0A1W2PPU9 A0A494BZV2 1 0 YSCPESPSQELGGPLPS(1)PGPR 186.88 1.45E-10 17049000 1424.4 1091.4 1203.6 1155.8 1627.7 1778.1 1210.6 1068.3 1475.6 1150.3 TRUE FALSE FALSE 1311.657237 1185.735753 1248.206475 1151.017606 1608.290741 1409.302017 1244.566178 1394.019752 1313.730372 1190.272839 1.101980314 0.996188196 1.048672568 0.96701997 1.351195026 1.184015942 1.045614196 1.171176646 1.103722044 1 10.2170766 -5.793855244 24.99999454 1.039919768 1.177545838 0.459221308 0.080288136 144.0434664 111089.8579 0.01204561 0.02183567 1.61E-06 5.793855244 0.13762607 YSDEQLNSGRQS(ph)PSQNER ddPTM_HeLa_Curcumin_4h_R1 1 YSDEQLNSGRQSPSQNER 18 1 P25054-2;P25054-3;P25054;A0A2Q2SV78;E9PFT7 P25054-2 APC Adenomatous polyposis coli protein 1 0 Y(0.007)S(0.002)DEQLNS(0.412)GRQS(0.528)PS(0.05)QNER 57.985 0.014148 60068000 2091.3 1301 1730.2 1401.2 1600.3 1490 1402.2 768.41 1923.2 1692.9 TRUE FALSE FALSE 1925.771398 1413.452643 1794.322734 1395.402206 1581.217468 1180.957204 1441.541958 1002.694672 1712.229772 1751.728149 1.099355171 0.806890409 1.024315751 0.796586049 0.902661448 0.674166939 0.822925611 0.572403128 0.977451765 1 10.77456318 -5.55460745 0.525002176 1.045961206 0.604939968 0.611504343 0.097437188 0.618095764 0.245508457 0.02187605 0.133224555 2.79E-06 5.55460745 -0.441021238 YSDFEWLKNELER ddPTM_HeLa_Curcumin_4h_R1 1 YSDFEWLKNELER 13 1 A0A087X0R6;Q9UMY4-3;Q9UMY4;Q9UMY4-1 A0A087X0R6 SNX12 Sorting nexin-12 0 0 148.13 0.00054799 16261000 1921.3 1525.6 1511.9 1420 1403.5 2642.5 1683.1 1827.7 2340.8 1702.4 FALSE FALSE TRUE 1769.227078 1657.466066 1567.932344 1414.124416 1386.764179 2094.415713 1730.323256 2384.957316 2084.020096 1761.558273 1.004353421 0.940909019 0.890082586 0.802769024 0.787237187 1.188956247 0.98226853 1.353890673 1.183054871 1 10.78263649 -2.98849894 1.172743877 0.967817411 7.247023204 0.443151213 0.127677072 16.88497591 1.668256392 0.016704611 247.1839147 0.001026836 2.98849894 6.279205793 YSDIDIILLKGDVEEDETIPDSEQDIRPR ddPTM_HeLa_Curcumin_4h_R1 1 YSDIDIILLKGDVEEDETIPDSEQDIRPR 29 2 Q92973-2;Q92973;Q92973-3 Q92973-2 TNPO1 Transportin-1 0 0 64.547 0.00031616 2461100 348.25 299.58 404.15 610.99 310.26 485.1 465.86 287.99 518.06 486.97 FALSE FALSE TRUE 320.685645 325.4743603 419.1281545 608.4618853 306.5603521 384.4847918 478.9307778 375.7968253 461.2301141 503.8921713 0.636417201 0.645920653 0.831781437 1.20752399 0.608384828 0.763029898 0.950462827 0.74578818 0.915334948 1 8.976971232 -9.626397568 1.471939943 0.998973389 0.780921103 0.110407727 0.170104681 0.577613485 2.265046282 0.121327045 0.028290386 2.36E-10 9.626397568 -0.218052286 YSDTTDS(ph)DPENEPFDEDQHTQITK ddPTM_HeLa_Curcumin_4h_R1 1 YSDTTDSDPENEPFDEDQHTQITK 24 0 P60484;P60484-2 P60484 PTEN "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN" 1 0 YS(0.008)DT(0.102)T(0.219)DS(0.671)DPENEPFDEDQHTQITK 71.296 0.00043243 9272600 396.5 308.22 414.19 397.15 521.71 353.77 267.02 268.2 235.53 214.26 TRUE FALSE FALSE 365.1166066 334.8611634 429.5402458 395.5066985 515.488949 280.3941142 274.5118626 349.9729454 209.6929483 221.7055191 1.646853936 1.510387133 1.937435963 1.783928069 2.325106525 1.264714182 1.238182359 1.578548639 0.945817448 1 7.792500874 -9.030670811 0.715924994 0.975380837 1.669795985 0.451237342 0.301482387 0.633103248 0.565548853 0.251918123 0.067591595 9.32E-10 9.030670811 0.694415148 S(ph)AEALGPGALVSPR ddPTM_HeLa_Curcumin_4h_R1 1 SAEALGPGALVSPR 14 0 Q9P227-2;Q9P227 Q9P227-2 ARHGAP23 Rho GTPase-activating protein 23 1 0 S(1)AEALGPGALVSPR 140.03 0.00076716 5758200 648.6 450.21 574.46 543.58 455.8 550.55 469.33 251 653.3 648.47 TRUE FALSE FALSE 597.2626256 489.1241463 595.7499929 541.33081 450.3648827 436.359724 482.4981367 327.5287445 581.6346245 671.0042842 0.890102552 0.728943403 0.88784827 0.806747174 0.671180339 0.650308402 0.719068638 0.488117218 0.866812088 1 9.390178168 -3.60260618 0.177042197 1.052033656 1.69E-18 0.720447164 0.074727817 6.196977705 0.153794354 0.103014513 1.511763053 0.000249686 3.60260618 -1.052033656 down YSEGYPGK(ac)R ddPTM_HeLa_Curcumin_4h_R1 1 YSEGYPGKR 9 1 P34897-3;P34897-2;P34897;G3V241;G3V3Y8;G3V4T0;G3V4X0;G3V2W0;G3V2E4;G3V540;G3V5L0;G3V4W5 P34897-3 SHMT2 "Serine hydroxymethyltransferase, mitochondrial" 0 1 YSEGYPGK(1)R 80.165 0.0089459 0 1272.1 1185.9 1340.9 1040.5 1746.4 2216.8 1251.1 862.99 1701.7 1010.6 FALSE TRUE FALSE 1171.411943 1288.403912 1390.594934 1036.194687 1725.575321 1757.010692 1286.202499 1126.111678 1515.027767 1045.718275 1.120198404 1.232075543 1.329798825 0.990892778 1.650134039 1.680195072 1.229970375 1.076878645 1.448791519 1 10.03027851 -7.111264575 0.710398118 1.027918381 1.370473924 0 0.242622912 0.571792516 0.599397881 0.053936814 0.071100941 7.74E-08 7.111264575 0.342555543 YSEWTSPAEDSS(ph)PGISLSSSR ddPTM_HeLa_Curcumin_4h_R1 1 YSEWTSPAEDSSPGISLSSSR 21 0 H0YNU5;A0A3B3IT82;P54132 H0YNU5 BLM Bloom syndrome protein 1 0 YSEWTS(0.001)PAEDS(0.231)S(0.768)PGISLSSSR 203.17 5.34E-39 0 1330.4 1030.7 1236.8 1236 1032.2 1699.9 1158.1 624.43 1427.8 1271.4 TRUE FALSE FALSE 1225.097436 1119.789115 1282.636896 1230.885759 1019.891689 1347.321578 1190.593169 814.8158325 1271.173912 1315.581055 0.931221555 0.851174552 0.974958472 0.935621378 0.77524048 1.024126619 0.904994158 0.619358138 0.966245224 1 10.36148442 -4.273186154 3.976371012 0.946638911 0.593073257 0.635024863 0.070027921 0.104771079 3.407762254 0.009855459 0.104614431 5.33E-05 4.273186154 -0.353565654 YSGAQDSGIGS(ph)DSVK ddPTM_HeLa_Curcumin_4h_R1 1 YSGAQDSGIGSDSVK 15 0 Q7Z7G8-2;Q7Z7G8-6;Q7Z7G8 Q7Z7G8-2 VPS13B Vacuolar protein sorting-associated protein 13B 1 0 YSGAQDS(0.017)GIGS(0.966)DS(0.016)VK 122.46 0.0013619 0 2111.1 1933.9 1583.3 1764.8 1508 1613.7 1140.9 708.69 2056.1 1556.3 TRUE FALSE FALSE 1944.004207 2101.057699 1641.978491 1757.497725 1490.018085 1279.00043 1172.910583 924.7663186 1830.550974 1610.381309 1.207170126 1.30469578 1.019620932 1.09135502 0.925257935 0.794222103 0.728343391 0.574253013 1.136718964 1 10.65318662 -5.174115472 1.058065974 1.114788046 0.593810638 0.840201191 0.085867068 0.240401941 0.440667083 0.016989366 0.097251093 6.70E-06 5.174115472 -0.520977408 YSGLTAS(ph)SK ddPTM_HeLa_Curcumin_4h_R1 1 YSGLTASSK 9 0 Q96AT1 Q96AT1 KIAA1143 Uncharacterized protein KIAA1143 1 0 YSGLT(0.002)AS(0.813)S(0.185)K 112.83 0.008235 9194500 3727.9 3167.9 3597.5 3524.7 3775.8 5343.5 5523.5 2455.8 3314.6 2206.1 TRUE FALSE FALSE 3432.832781 3441.71916 3730.826515 3510.115725 3730.776051 4235.197866 5678.474544 3204.562115 2950.996673 2282.761811 1.503806821 1.50769964 1.6343477 1.53766184 1.634325593 1.855295566 2.487545795 1.403809237 1.292730875 1 11.15656462 -8.896021809 0.107134499 3.01E-13 2.523648258 0.430735672 0.279040814 11.46578475 0.406067717 6.427674911 3.163281497 1.27E-09 8.896021809 2.523648258 YSHSGSS(ph)S(ph)PDTK ddPTM_HeLa_Curcumin_4h_R1 2 YSHSGSSSPDTK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 2 0 Y(0.017)S(0.005)HS(0.002)GS(0.256)S(0.417)S(0.862)PDT(0.441)K;YSHSGS(0.348)S(0.65)S(0.983)PDT(0.02)K ; 174.23 0.00033219 125072000 11902.8 22261 13712.4 11098.8 11965.5 9547.2 6409.9 4184.4 9846 11073.1 TRUE FALSE FALSE 10960.68082 24185.14165 14220.59361 11052.87611 11822.81923 7567.003101 6589.744543 5460.204297 8765.918433 11457.8894 0.95660557 2.11078505 1.241118072 0.964652016 1.031849655 0.660418585 0.575127261 0.476545383 0.765055249 1 13.4840537 -5.186022795 1.824388919 1.095007182 0.509295932 0.368630089 0.34784612 0.353878123 2.226179582 0.053469895 0.189919761 6.52E-06 5.186022795 -0.58571125 YSHSGSSS(ph)PDTK ddPTM_HeLa_Curcumin_4h_R1 3 YSHSGSSSPDTK 12 0 Q9UQ35;Q9UQ35-2;I3L4D8;I3L182 Q9UQ35 SRRM2 Serine/arginine repetitive matrix protein 2 1 0 YSHSGSS(0.045)S(0.955)PDTK;YSHSGSS(0.001)S(0.999)PDTK;YSHSGSS(0.001)S(0.999)PDTK ;; 193.15 4.16E-06 15208800 13267.8 30447.2 8437.41 8256.65 10081.08 12158.47 6315.51 3564.74 8354.91 8302.66 TRUE FALSE FALSE 12217.63963 33078.9203 8750.107837 8222.48617 9960.869705 9636.666268 6492.706213 4651.612816 7438.397276 8591.176817 1.422114792 3.85033634 1.018499331 0.957084966 1.159430183 1.121693392 0.755741193 0.541440703 0.865818203 1 13.06864005 -4.856801059 0.978415127 1.395088161 0.460088437 0.141884487 0.823779874 1.740454007 2.203399756 0.134048505 1.371781208 1.39E-05 4.856801059 -0.934999724 YSHSYLS(ph)DSDTEAK ddPTM_HeLa_Curcumin_4h_R1 1 YSHSYLSDSDTEAK 14 0 Q92614;A0A0D9SFK2;Q92614-2;Q92614-3;Q92614-4;Q92614-5 Q92614 MYO18A Unconventional myosin-XVIIIa 1 0 YSHS(0.002)YLS(0.988)DS(0.01)DTEAK 122.01 0.00076642 46121000 5166.6 3758.5 4204.4 4260.5 4746.1 4773.3 3096.4 2961.1 4230.4 4062.1 TRUE FALSE FALSE 4757.658158 4083.367992 4360.218763 4242.87118 4689.505857 3783.263774 3183.27665 3863.925759 3766.335704 4203.257673 1.131897811 0.971476962 1.037342724 1.009424477 1.115683649 0.900078955 0.757335595 0.919269305 0.896051586 1 12.03729219 -5.097288759 4.741736712 1.05338648 0.835756225 0.465743382 0.077504119 0.096181318 3.524373981 0.009376705 0.025211008 7.99E-06 5.097288759 -0.217630254 YSHSYLSDS(ph)DTEAK ddPTM_HeLa_Curcumin_4h_R1 1 YSHSYLSDSDTEAK 14 0 Q92614;A0A0D9SFK2;Q92614-2;Q92614-3;Q92614-4;Q92614-5 Q92614 MYO18A Unconventional myosin-XVIIIa 1 0 YSHSYLS(0.283)DS(0.677)DT(0.039)EAK 131.08 0.0010566 19098000 3364.7 2241.6 2603.5 2405 3331.6 2967.7 2100.2 2157 3143.3 2159.3 TRUE FALSE FALSE 3098.380445 2435.353916 2699.988 2395.048747 3291.872846 2352.165567 2159.12596 2814.65937 2798.487854 2234.335514 1.386712257 1.089967867 1.208407593 1.071928872 1.473311785 1.05273606 0.966339185 1.259729952 1.252492223 1 11.12563013 -9.701510729 1.598513927 1.000289121 1.214172097 0 0.167630867 0.50337914 2.324794399 0.111756531 0.024801675 1.99E-10 9.701510729 0.213882976 YSIAITWGGHHIPK ddPTM_HeLa_Curcumin_4h_R1 2 YSIAITWGGHHIPK 14 0 O75369-8;O75369-2;O75369-9;O75369;E7EN95;O75369-7;O75369-6;O75369-3;O75369-5;O75369-4 O75369-8 FLNB Filamin-B 0 0 ; ; 84.718 0.0045469 6130500 2936.6 2374 3855.9 2016.5 3197.7 8687.5 4727.5 4357.8 3837.2 3356.3 FALSE FALSE TRUE 2704.165011 2579.197982 3998.803046 2008.156257 3159.569516 6885.614572 4860.140927 5686.473159 3416.26876 3472.931175 0.778640542 0.742657384 1.151420182 0.57823094 0.909770265 1.982652182 1.399434852 1.637369954 0.983684556 1 11.76193811 -5.281061852 23.17436413 0.877578275 1.645780478 0.770916652 0.198522535 100.4568396 118640.6776 0.026940026 0.060348005 5.24E-06 5.281061852 0.768202203 YSLDPENPTK ddPTM_HeLa_Curcumin_4h_R1 1 YSLDPENPTK 10 0 A0A087WXM6;J3QQT2;J3KRX5;A0A0A6YYL6;P18621;P18621-3;J3KRB3;A0A087WWH0;J3QS96;J3KSJ0;A0A087WY81 A0A087WXM6 RPL17;RPL17-C18orf32 60S ribosomal protein L17 0 0 187.5 2.11E-16 7872200 15230 13305 13782 15217 13399 17429 12962 12991 15332 14050 FALSE FALSE TRUE 14024.52943 14455.02491 14292.77304 15154.03609 13239.22568 13814.02893 13325.67883 16951.8961 13650.11796 14538.23645 0.964665107 0.994276366 0.983116012 1.042357244 0.910648669 0.950186013 0.916595275 1.166021488 0.938911539 1 13.82756465 -4.249817753 24.90708634 0.97726825 1.166021606 0.690675043 0.039445771 747.3230303 1601607.411 0.005189724 0.1128101 5.63E-05 4.249817753 0.188753356 YSLEPVAVELK ddPTM_HeLa_Curcumin_4h_R1 2 YSLEPVAVELK 11 0 P00558;P00558-2 P00558 PGK1 Phosphoglycerate kinase 1 0 0 ; ; 160.75 1.05E-07 1195200 1363.27 1177.52 1520.1 1141.56 1467.93 1947.02 1561.52 1564.66 1050.11 880.25 FALSE FALSE TRUE 1255.365741 1279.299582 1576.436243 1136.836527 1450.425893 1543.186105 1605.332049 2041.717631 934.9155602 910.838622 1.378252646 1.404529355 1.730752523 1.248120688 1.592407105 1.694247551 1.762476919 2.241579992 1.026433814 1 9.831051657 -1 0.136982325 0.870729151 4.894461915 0.803694749 0.15847664 24.31898142 0.221492944 0.459490069 19.1553109 0.1 1 4.023732764 up YSLS(ph)PSK ddPTM_HeLa_Curcumin_4h_R1 1 YSLSPSK 7 0 P49792;J3KNE0;J3KQ37;A6NKT7;Q99666;O14715;F8VYC4;P0DJD0;P0DJD1;A0A1W2PNU4;A0A286YES2;Q7Z3J3;F8W705;Q99666-2 P49792 RANBP2;RGPD3;RGPD8;RGPD5;RGPD1;RGPD2;RGPD4 E3 SUMO-protein ligase RanBP2;RanBP2-like and GRIP domain-containing protein 3;RANBP2-like and GRIP domain-containing protein 5/6;RANBP2-like and GRIP domain-containing protein 8;RANBP2-like and GRIP domain-containing protein 1;RANBP2-like and GRIP domain-containing protein 2;RanBP2-like and GRIP domain-containing protein 4 1 0 YSLS(0.973)PS(0.027)K 101.46 0.018848 138490000 4714.5 2745.1 3494.7 3618.3 4695.1 5816.8 4605.7 2379.3 4381.6 4417.3 TRUE FALSE FALSE 4341.34235 2982.374212 3624.216656 3603.328433 4639.113999 4610.330111 4734.923546 3104.737617 3900.949442 4570.800846 0.949799061 0.652483955 0.792906271 0.788336345 1.014945554 1.008648214 1.035906771 0.679254626 0.853449882 1 12.15823125 -7.49906034 20.6082642 0.97785335 0.862874051 0.044488874 0.133684073 47.17796927 40822.37414 0.023263946 0.025100968 3.17E-08 7.49906034 -0.114979299 YSPDEMNNS(ph)PNFEEK ddPTM_HeLa_Curcumin_4h_R1 1 YSPDEMNNSPNFEEK 15 0 Q14687-2;Q14687-3;Q14687;H7C3B5;H0Y613 Q14687-2 GSE1 Genetic suppressor element 1 1 0 YS(0.001)PDEMNNS(0.999)PNFEEK 86.498 0.012283 5663500 2130.1 2217.9 2349.1 2373.2 2375.9 2890 2196.1 2148.1 2710.5 2120.1 TRUE FALSE FALSE 1961.500337 2409.605393 2436.159712 2363.380327 2347.568944 2290.581423 2257.716655 2803.045801 2413.164931 2193.773317 0.894121704 1.098383946 1.110488351 1.077312915 1.070105524 1.044128582 1.029147651 1.277728095 1.10000651 1 11.09919874 -7.247918533 24.14891962 0.950001917 1.094348788 0.177538858 0.083474392 318.4492611 568766.5974 0.01186946 0.014489684 5.65E-08 7.247918533 0.144346872 YSPSQNS(ph)PIHHIPSR ddPTM_HeLa_Curcumin_4h_R1 2 YSPSQNSPIHHIPSR 15 0 E9PK91;Q9NYF8-3;A0A1W2PQ43;E9PQN2;E9PKI6;E9PK09;E9PJA7;H0YF00;Q9NYF8-2;Q9NYF8;Q9NYF8-4 E9PK91;Q9NYF8-2 BCLAF1 Bcl-2-associated transcription factor 1 1 0 YSPSQNS(1)PIHHIPSR;YSPS(0.004)QNS(0.996)PIHHIPSR ; 109.03 0.0011022 29410800 3774.7 3704 3867.9 3657.9 3655.8 4570 3287.7 2262.3 4333.7 4200.8 TRUE FALSE FALSE 3475.928512 4024.157255 4011.247777 3642.764579 3612.206973 3622.130485 3379.944014 2952.064856 3858.303952 4346.777487 0.799656417 0.925779446 0.92280955 0.838037969 0.831008025 0.833290983 0.777574657 0.67913871 0.887623984 1 12.08573053 -13.52287874 0.026461484 2.127452286 2.03E-06 0.536729541 0.058039537 873.3158154 1.858858508 108.1543827 51.24158141 3.00E-14 13.52287874 -2.127450252 YSPT(ph)SPTYSPT(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 2 0 YS(0.018)PT(0.855)S(0.084)PT(0.029)Y(0.071)S(0.084)PT(0.781)S(0.078)PK 117.48 0.0072212 106770000 3014.3 2336.1 2557.4 2920.1 2740.2 2854.7 1780.8 1458.4 3041.4 3060.1 TRUE FALSE FALSE 2775.714974 2538.022075 2652.179494 2908.0174 2707.524905 2262.603041 1830.764455 1903.059446 2707.766029 3166.438247 0.876604802 0.801538472 0.837590784 0.91838753 0.855069543 0.714557766 0.578177849 0.601009493 0.855145693 1 11.62864523 -3.360068321 0.270053257 0.974183236 7.29E-13 0.728765366 0.066558949 4.664274889 0.176140485 0.034769211 1.644195931 0.000436447 3.360068321 -0.974183236 YSPTS(ph)PTYSPT(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 2 0 YSPT(0.348)S(0.649)PT(0.002)YSPT(0.999)S(0.001)PK 227.92 1.07E-19 26456000 3484 3272 3510.4 3381.3 3034.5 3641.7 2250.3 2396.8 3926.3 3066.1 TRUE FALSE FALSE 3208.237724 3554.8171 3640.498512 3367.309077 2998.315569 2886.37037 2313.437362 3127.573286 3495.594713 3172.646747 1.011218071 1.120457897 1.147464185 1.061356446 0.945051816 0.909767333 0.729182145 0.985793105 1.101791341 1 11.63147118 -5.398676515 2.481237436 1.029828295 0.856313948 0.517290603 0.080784647 0.19626122 2.337750977 0.011733687 0.030333154 3.99E-06 5.398676515 -0.173514347 YSPTS(ph)PTYSPTTPK ddPTM_HeLa_Curcumin_4h_R1 2 YSPTSPTYSPTTPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 0 YSPT(0.003)S(0.978)PT(0.019)YSPTTPK;YS(0.001)PT(0.258)S(0.577)PT(0.064)Y(0.096)S(0.002)PT(0.001)TPK ; 179.5 0.00013934 223151000 12856.2 10967.9 11221.5 12481.9 11919.1 12916.9 8402.2 9179.5 13460.1 10449.4 TRUE FALSE FALSE 11838.6182 11915.9164 11637.37866 12430.25321 11776.97252 10237.78934 8637.943119 11978.28729 11983.56071 10812.51587 1.094899498 1.102048454 1.076287776 1.149617106 1.089198171 0.946846179 0.79888374 1.107816852 1.108304565 1 13.40041463 -5.226998969 8.045234105 1.063217999 0.935497195 0.345101435 0.080824707 0.261932574 55.13173935 0.011312703 0.028684746 5.93E-06 5.226998969 -0.127720804 YSPTSPTYS(ph)PTSPK ddPTM_HeLa_Curcumin_4h_R1 1 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 0 YSPT(0.007)S(0.012)PT(0.042)Y(0.002)S(0.896)PT(0.042)SPK 238.64 1.65E-28 93032000 4106.2 3462.2 3471.2 3432.1 3041.9 3790 4708.1 2792.4 4117.4 3169.5 TRUE FALSE FALSE 3781.189937 3761.457141 3599.845726 3417.89888 3005.627329 3003.911278 4840.196615 3643.789905 3665.731521 3279.639889 1.15292839 1.146911633 1.09763445 1.04215676 0.916450413 0.915927169 1.475831731 1.111033537 1.117723788 1 11.6793217 -4.767302536 24.99982929 1.059162604 1.293432636 0.417232715 0.115157723 95.18456256 405864.3942 0.016297822 0.050862044 1.71E-05 4.767302536 0.234270032 YSPTSPTYSPT(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 2 YSPTSPTYSPTSPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 0 YSPTSPTY(0.001)S(0.381)PT(0.605)S(0.013)PK;YSPTSPTYS(0.005)PT(0.869)S(0.126)PK ; 218.45 1.66E-13 41158000 7294.6 5687.4 6328.7 6762.4 5911.1 6425.4 4869.5 3837.7 7528.4 6175 TRUE FALSE FALSE 6717.224713 6178.993513 6563.247189 6734.418981 5840.613993 5092.699611 5006.125064 5007.797063 6702.553355 6389.58079 1.051277843 0.967042082 1.027179623 1.053968829 0.914084067 0.797031883 0.783482552 0.783744228 1.048981706 1 12.64150557 -5.4542498 2.619930459 1.022080954 0.785061668 0.94164637 0.026366407 0.048452342 0.650160239 0.004152125 0.010211949 3.51E-06 5.4542498 -0.237019287 YSPTSPTYSPT(ph)TPK ddPTM_HeLa_Curcumin_4h_R1 1 YSPTSPTYSPTTPK 14 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 1 0 YSPTSPT(0.003)Y(0.002)S(0.29)PT(0.68)T(0.026)PK 103.43 0.011509 7049100 3505.2 2686.1 2752.6 3183.6 3053.4 3646 2730.1 1680.1 3662 2702.2 TRUE FALSE FALSE 3227.759721 2918.274515 2854.613777 3170.427107 3016.990199 2889.778501 2806.699258 2192.354756 3260.287762 2796.101249 1.154378699 1.04369415 1.02092647 1.133874214 1.07899891 1.033502811 1.003790281 0.784075597 1.166012055 1 11.44920089 -3.982841905 1.41286577 1.072667851 0.47658917 0.733435022 0.053676718 1.093472538 1.163314535 0.008902833 1.111296705 0.00010403 3.982841905 -0.596078681 S(ph)VIEPLPVTPTR ddPTM_HeLa_Curcumin_4h_R1 1 SVIEPLPVTPTR 12 0 H0YCM0;E9PM17;B3KNX7;Q13153;Q13153-2 H0YCM0 PAK1 Non-specific serine/threonine protein kinase;Serine/threonine-protein kinase PAK 1 1 0 S(0.869)VIEPLPVT(0.128)PT(0.003)R 127.52 0.002791 6891100 1106.1 1169.8 1190.9 1424.4 1397 2051.6 2056.8 2492.9 1277.1 987.13 TRUE FALSE FALSE 1018.551018 1270.912299 1235.035802 1418.50621 1380.341687 1626.075034 2114.508272 3252.973734 1137.005325 1021.432694 0.99717879 1.244244782 1.209121079 1.388741734 1.351378016 1.591955146 2.070139604 3.184716676 1.113147574 1 9.996378427 -1 0.505719692 1.017599444 72.49530626 0.976064892 0.097926368 9.425839275 0.089170707 0.01982101 722.0881458 0.1 1 71.47770681 up YSS(ph)YQGSR ddPTM_HeLa_Curcumin_4h_R1 2 YSSYQGSR 8 0 Q5VWV2;Q8TEW0-4;Q8TEW0-11;Q8TEW0-2;Q8TEW0;Q8TEW0-3;Q8TEW0-7;Q8TEW0-6;Q8TEW0-5 Q5VWV2 PARD3 Partitioning defective 3 homolog 1 0 YS(0.021)S(0.979)YQGSR;YS(0.041)S(0.959)YQGSR ; 147.73 0.0021918 32716000 3366.4 3323.7 2683.8 2815.3 3135.5 4036.3 3253.2 1969.67 3100.1 3425.7 TRUE FALSE FALSE 3099.945888 3610.985818 2783.263989 2803.651035 3098.11121 3199.125882 3344.476036 2570.213316 2760.026786 3544.74282 0.874519266 1.018687674 0.785180796 0.790932143 0.874001689 0.902498727 0.943503156 0.725077515 0.778625397 1 11.79146524 -13.52287875 0.162972224 1.54021445 0.825985529 0 0.103771942 54.25711582 0.586238049 9.29041242 0.138773469 3.00E-14 13.52287875 -0.71422892 YSSEVATES(ph)PLDFTK ddPTM_HeLa_Curcumin_4h_R1 1 YSSEVATESPLDFTK 15 0 Q8WTT2 Q8WTT2 NOC3L Nucleolar complex protein 3 homolog 1 0 Y(0.406)S(0.079)S(0.053)EVAT(0.008)ES(0.452)PLDFT(0.003)K 169.98 0.00017334 9543300 3556.8 2862.2 3142.9 3550.3 3175.8 4063.7 3219.2 2585.8 3559.4 2825.6 TRUE FALSE FALSE 3275.275527 3109.595814 3259.378639 3535.609799 3137.930659 3220.842813 3309.522088 3374.198516 3168.942725 2923.78939 1.120215956 1.063549866 1.114778872 1.209255978 1.073241004 1.101598776 1.13192903 1.154049785 1.083847809 1 11.51362368 -9.86972061 0.359325731 0.922666503 1.130871053 0.252102425 0.046198733 2.252399348 0.270947057 0.193124489 0.01454651 1.35E-10 9.86972061 0.20820455 YSSS(ph)QPEPR ddPTM_HeLa_Curcumin_4h_R1 1 YSSSQPEPR 9 0 E7EPP6;O14757-2;O14757-3;O14757 E7EPP6 CHEK1 Serine/threonine-protein kinase Chk1 1 0 YS(0.006)S(0.108)S(0.885)QPEPR 93.442 0.016975 10761000 3205.7 3117.9 2803.6 2783.6 2867.3 3367.1 2510.2 2719.7 2861.9 2710.6 TRUE FALSE FALSE 2951.965462 3387.397383 2907.503882 2772.082201 2833.10932 2668.725505 2580.629456 3548.92401 2547.95673 2804.793148 1.052471718 1.207717362 1.036619718 0.988337483 1.010095636 0.951487459 0.920078352 1.26530686 0.908429462 1 11.45367866 -6.501629485 23.88822863 1.04314237 1.015626796 0 0.111148365 2091.226418 2350934.814 0.015582832 0.023648626 3.15E-07 6.501629485 -0.027515575 YSSSGTPSSAS(ph)PALSR ddPTM_HeLa_Curcumin_4h_R1 2 YSSSGTPSSASPALSR 16 0 Q14934-2;Q14934-9;Q14934-3;Q14934-4;Q14934-5;Q14934-6;Q14934-7;Q14934;Q14934-8;Q14934-10;Q14934-18;Q14934-11;Q14934-12;Q14934-13;Q14934-14;Q14934-15;Q14934-16;Q14934-17 Q14934-2 NFATC4 "Nuclear factor of activated T-cells, cytoplasmic 4" 1 0 YSSSGTPSSAS(1)PALSR;YSSSGT(0.002)PSS(0.001)AS(0.996)PALSR ; 244.18 2.68E-30 16863300 3141.5 1989.74 2542.7 2979.3 3817.3 3105.4 1573.4 1085.46 2611.9 2250.6 TRUE FALSE FALSE 2892.84696 2161.724259 2636.934699 2966.972446 3771.781191 2461.305035 1617.545369 1416.411757 2325.381105 2328.808182 1.242200617 0.928253463 1.132310818 1.274030411 1.619618661 1.056894704 0.694580765 0.608213149 0.998528398 1 11.1853761 -4.775960257 4.135346725 1.151337289 0.634771477 0.54979307 0.184925067 0.119537313 4.579213579 0.027463112 0.10050247 1.68E-05 4.775960257 -0.516565811 YSSSSIPEPFGSRGS(ph)PR ddPTM_HeLa_Curcumin_4h_R1 1 YSSSSIPEPFGSRGSPR 17 1 Q8WUF5;K7EN03 Q8WUF5 PPP1R13L RelA-associated inhibitor 1 0 YSSSSIPEPFGS(0.009)RGS(0.991)PR 203.05 1.31E-09 55831000 2461.3 2359.4 1807.5 2267.5 1892.3 2536.7 1901.9 920.96 2875 2001.4 TRUE FALSE FALSE 2266.485508 2563.336023 1874.48754 2258.117686 1869.735558 2010.559825 1955.262195 1201.756464 2559.619693 2070.948501 1.094419058 1.237759423 0.905134792 1.090378483 0.9028402 0.970840088 0.944138492 0.580292781 1.235964917 1 11.01607596 -3.843521675 0.998818056 1.046805163 1.29E-30 0.628930566 0.110273899 1.713368974 0.750359219 0.013920728 2.344624182 0.000143377 3.843521675 -1.046805163 YSVLNNDDYFADVS(ph)PLR ddPTM_HeLa_Curcumin_4h_R1 4 YSVLNNDDYFADVSPLR 17 0 Q1ED39;H3BMC9 Q1ED39 KNOP1 Lysine-rich nucleolar protein 1 1 0 YSVLNNDDYFADVS(1)PLR;YSVLNNDDYFADVS(1)PLR;YSVLNNDDYFADVS(1)PLR;YSVLNNDDYFADVS(1)PLR ;;; 265.38 4.22E-52 106770000 10420.1 9403.5 9462.1 9395.5 10152.9 11532.8 11194 3513.37 9283.2 9425.2 TRUE FALSE FALSE 9595.33809 10216.29664 9812.77375 9356.62391 10031.8333 9140.767279 11508.07351 4584.580339 8264.856185 9752.724998 0.983862263 1.047532525 1.006157125 0.959385599 1.028618494 0.937252643 1.179985441 0.470081986 0.847440709 1 13.25158966 -4.249409553 24.97395775 1.002754376 0.470081659 0.79528742 0.080470277 425.9095786 884173.9061 0.007641871 0.172406198 5.63E-05 4.249409553 -0.532672717 TKSNS(ph)LSEQLAINTSPDAVK ddPTM_HeLa_Curcumin_4h_R1 1 TKSNSLSEQLAINTSPDAVK 20 1 Q5T1M5;Q5T1M5-2;Q5T1M5-3 Q5T1M5 FKBP15 FK506-binding protein 15 1 0 T(0.217)KS(0.259)NS(0.373)LS(0.151)EQLAINTSPDAVK 89.297 0.00057007 20240000 1498.3 1106.4 1321.7 1355.9 1136.7 1680.6 1014.5 516.58 1833.8 1519.6 TRUE FALSE FALSE 1379.707974 1202.032286 1370.683365 1350.289645 1123.145595 1332.024616 1042.96414 674.082864 1632.636728 1572.405987 0.877450217 0.764454152 0.871710853 0.858741099 0.714284736 0.847125123 0.66329189 0.428695178 1.038304828 1 10.61875805 -3.51478781 0.27716603 0.971912838 9.93E-28 0.763477565 0.081140581 4.809175351 0.201136962 0.040280508 1.710300009 0.000305641 3.51478781 -0.971912838 down YSVQTADHR ddPTM_HeLa_Curcumin_4h_R1 1 YSVQTADHR 9 0 Q16658 Q16658 FSCN1 Fascin 0 0 110.53 0.00097907 963410 1156.1 453.21 693.02 640.99 1004.1 1564.8 817.56 798.94 869.54 759.52 FALSE FALSE TRUE 1064.593465 492.3834529 718.7039308 638.3377532 992.1267633 1240.242841 840.4985332 1042.533128 774.1536375 785.9132635 1.354594094 0.626511189 0.914482506 0.812224177 1.262387097 1.578091246 1.069454573 1.32652441 0.985036993 1 9.618226289 -5.543015186 24.96238435 1.081159027 1.319345381 0.284311145 0.229532355 333.4486034 413362.6113 0.038175312 0.076357227 2.86E-06 5.543015186 0.238186354 YSYYDESQGEIYR ddPTM_HeLa_Curcumin_4h_R1 1 YSYYDESQGEIYR 13 0 Q9Y316-2;Q9Y316;Q9Y316-3 Q9Y316-2 MEMO1 Protein MEMO1 0 0 135.1 0.011171 8985400 3807.8 2510.9 2836.7 2727 3329.1 3639.9 2259.7 782.35 3640.6 3054.8 FALSE FALSE TRUE 3506.408612 2727.931008 2941.830597 2715.716397 3289.402657 2884.94371 2323.1011 1020.884914 3241.235288 3160.954073 1.10928806 0.863008745 0.930678058 0.859144529 1.040636017 0.912681312 0.734936683 0.322967335 1.02539778 1 11.62614436 -4.235150673 1.249813645 1.015966934 8.48E-17 0.854058024 0.081003947 0.445086982 0.554487127 0.014125789 0.589227094 5.82E-05 4.235150673 -1.015966934 down YT(ph)LLSGLYKY(ph)MFQK ddPTM_HeLa_Curcumin_4h_R1 1 YTLLSGLYKYMFQK 14 1 Q13795-4;Q13795-2;Q13795 Q13795-4 ARFRP1 ADP-ribosylation factor-related protein 1 2 0 Y(0.444)T(0.548)LLS(0.012)GLY(0.018)KY(0.978)MFQK 50.222 0.0096741 0 1410.2 1267.8 1309.4 1146.5 1383.8 1158 1069.6 1139.4 1554.1 1161 TRUE FALSE FALSE 1298.581182 1377.382983 1357.927516 1141.756087 1367.299089 917.8177467 1099.610097 1486.797815 1383.619118 1201.344664 1.080939735 1.1465344 1.130339658 0.950398434 1.138140561 0.763992029 0.915316088 1.23761137 1.151725363 1 10.2304344 YTCGEAPDYDR ddPTM_HeLa_Curcumin_4h_R1 3 YTCGEAPDYDR 11 0 A0A0A0MTN3;P21266 A0A0A0MTN3 GSTM3 Glutathione S-transferase Mu 3 0 0 ;; ;; 223.31 9.93E-11 147705200 8193.8 7434 7174.7 7475.8 7448.1 7708.4 6023.1 6638.8 7555.1 6592.7 FALSE FALSE TRUE 7545.252084 8076.561835 7440.600694 7444.86712 7359.286272 6109.590948 6192.091976 8662.939559 6726.324432 6821.795834 1.106050704 1.183934851 1.090709965 1.091335376 1.078790168 0.895598622 0.907692362 1.269891355 0.986004946 1 12.73593586 -4.233369479 23.79598147 1.049891098 1.269891974 0.383139255 0.087142304 4692.418567 3977832.226 0.012765362 1.475054935 5.84E-05 4.233369479 0.220000876 QTVGTK(ac)QPK ddPTM_HeLa_Curcumin_4h_R1 2 QTVGTKQPK 9 1 A0A669KBI3;F5GXF9;P51825;P51825-3;P51825-2 A0A669KBI3 AFF1 AF4/FMR2 family member 1 0 1 ; QTVGTK(1)QPK;QTVGTK(1)QPK 171.33 7.05E-12 11078900 8218.6 6146.3 7516 6553.3 7118.9 7561.3 5972.8 2641.9 7929 7590.8 FALSE TRUE FALSE 7568.089138 6677.558785 7794.549572 6526.184181 7034.011767 5993.001147 6140.380693 3447.403148 7059.208537 7854.579735 0.963525662 0.85014845 0.992357304 0.830876304 0.895529997 0.762994501 0.781758019 0.438903578 0.898737905 1 12.93931837 -3.849966241 0.519833284 0.977108946 1.18E-23 0.800844974 0.069275038 1.483759409 0.20002622 0.011898632 0.967028751 0.000141265 3.849966241 -0.977108946 YTEFYHVPTHSDASK ddPTM_HeLa_Curcumin_4h_R1 1 YTEFYHVPTHSDASK 15 0 Q96HC4;Q96HC4-7;Q96HC4-4;H0YBI4;Q96HC4-3;Q96HC4-2;Q96HC4-6 Q96HC4 PDLIM5 PDZ and LIM domain protein 5 0 0 81.904 0.004965 2758900 1401.4 1166.4 1290.2 1223.2 1742.9 2426 1514.2 964.04 1681.6 1318.2 FALSE FALSE TRUE 1290.477711 1267.218419 1338.015947 1218.138723 1722.117056 1922.820253 1556.684377 1257.971358 1497.132687 1364.007352 0.946092929 0.929040754 0.980944821 0.893058766 1.262542356 1.40968467 1.141258055 0.922261421 1.097598693 1 10.41363571 -5.760386331 24.99987609 0.965599816 1.197013032 0.403566698 0.124073481 18.95119133 449889.4719 0.017261554 0.03301672 1.74E-06 5.760386331 0.231413217 YTGEDFDEDLR ddPTM_HeLa_Curcumin_4h_R1 2 YTGEDFDEDLR 11 0 Q14204;A0A2R8YFZ7;A0A2R8Y706;A0A2R8Y6H2 Q14204 DYNC1H1 Cytoplasmic dynein 1 heavy chain 1 0 0 ; ; 232.72 6.99E-16 74611000 4973.3 4625.2 4725.2 5081.5 4464.1 5073.2 4753 4183.1 5611.2 4731.2 FALSE FALSE TRUE 4579.658057 5024.981679 4900.320069 5060.474099 4410.868523 4020.961133 4886.356388 5458.507933 4995.665399 4895.608848 0.935462411 1.026426301 1.000962336 1.033676149 0.90098467 0.82134036 0.998110049 1.114980404 1.02043802 1 12.25727258 -4.306791379 4.383793904 0.965442678 1.120321577 0.324070658 0.063249086 0.163712343 6.468295457 0.008821945 0.068578134 4.93E-05 4.306791379 0.154878899 YTIS(ph)QEAYDQR ddPTM_HeLa_Curcumin_4h_R1 1 YTISQEAYDQR 11 0 K7EP07;K7EK42;A0A494C0X0;Q99426-2;Q99426 K7EP07 TBCB Tubulin-folding cofactor B 1 0 YT(0.012)IS(0.988)QEAYDQR 118.73 0.0043645 6533900 1038.5 1024 1069.5 1202.7 1320.4 971.23 1101.3 1181 1126.6 1012.5 TRUE FALSE FALSE 956.3016292 1112.509997 1109.136611 1197.723546 1304.655092 769.78595 1132.199514 1541.081463 1003.014799 1047.6843 0.91277652 1.061875221 1.058655371 1.143210361 1.245275025 0.734749915 1.080668589 1.470940687 0.957363586 1 10.03298834 -6.971090328 2.427233771 0.959190531 1.111031575 0.151621364 0.172740913 0.438456333 5.206473173 0.02912672 0.038338774 1.07E-07 6.971090328 0.151841044 YTLENKEEGSLS(ph)DTEADAVSGQLPDPTTNPSAGK ddPTM_HeLa_Curcumin_4h_R1 1 YTLENKEEGSLSDTEADAVSGQLPDPTTNPSAGK 34 1 Q8N1G4 Q8N1G4 LRRC47 Leucine-rich repeat-containing protein 47 1 0 YTLENKEEGS(0.004)LS(0.759)DT(0.233)EADAVS(0.003)GQLPDPTTNPSAGK 91.396 5.64E-11 23884000 4147.6 3527.9 3616.4 3527.2 4361.3 4356.1 3681.1 3621.6 3700.2 3074.3 TRUE FALSE FALSE 3819.313083 3832.835956 3750.426965 3512.605381 4309.294346 3452.595757 3784.381759 4725.809168 3294.297317 3181.131696 1.200614576 1.204865539 1.178959981 1.104199925 1.354641919 1.085335688 1.189633791 1.485574827 1.035574013 1 11.63532438 -13.52287875 0.107603733 0.263686254 1.367544259 0.440340928 0.103882356 76.11422999 0.604032072 12.4672155 0.684438942 3.00E-14 13.52287875 1.103858005 SETIQDTDTQSLVGS(ph)PSTR ddPTM_HeLa_Curcumin_4h_R1 1 SETIQDTDTQSLVGSPSTR 19 0 E9PMR6;Q9NZN5-2;Q9NZN5 E9PMR6 ARHGEF12 Rho guanine nucleotide exchange factor 12 1 0 SETIQDTDTQSLVGS(0.998)PS(0.002)TR 225.69 8.17E-25 6907400 853.22 871.55 1035 859.12 1033.6 1292.2 1088.4 1345.4 992.81 736.85 TRUE FALSE FALSE 785.6867367 946.8828984 1073.35801 855.5651891 1021.274995 1024.183154 1118.937575 1755.606267 883.9012269 762.4554827 1.030468997 1.241886143 1.407764827 1.12211822 1.339455245 1.343269446 1.467544795 2.30256888 1.159282407 1 9.574509295 -1 0.488888391 1.045844628 34.96428568 0.835871323 0.143151616 23.42885129 0.231352363 0.029083756 816.9006095 0.1 1 33.91844105 up YTPT(ph)SPSYSPSSPEY(ph)TPT(ph)SPK ddPTM_HeLa_Curcumin_4h_R1 1 YTPTSPSYSPSSPEYTPTSPK 21 0 P24928 P24928 POLR2A DNA-directed RNA polymerase II subunit RPB1 3 0 Y(0.016)T(0.219)PT(0.289)S(0.322)PS(0.185)Y(0.057)S(0.217)PS(0.183)S(0.182)PEY(0.264)T(0.138)PT(0.693)S(0.234)PK 47.12 0.014173 4512900 1963 1751.6 2165.9 2179.5 1952.2 2011 1193 1369.9 2302.9 1795.3 TRUE FALSE FALSE 1807.626479 1903.000499 2246.170159 2170.481806 1928.92129 1593.895931 1226.472369 1787.576204 2050.277632 1857.686541 0.973052471 1.024392682 1.209122265 1.168378926 1.038345946 0.858000473 0.660214919 0.962259328 1.103672544 1 10.85929137 -5.167749346 4.414884727 1.02373455 0.801444015 0.4986082 0.105660883 0.161180592 5.44672876 0.015543613 0.041488017 6.80E-06 5.167749346 -0.222290534 YTQVGPDHNR ddPTM_HeLa_Curcumin_4h_R1 4 YTQVGPDHNR 10 0 Q08211 Q08211 DHX9 ATP-dependent RNA helicase A 0 0 ;;; ;;; 158.08 0.0004995 11045400 10234.7 8036.3 8559.8 8624 9186.8 11219.3 8803.4 6861.97 10047.7 8823.2 FALSE FALSE TRUE 9424.612695 8730.921963 8877.033718 8588.316173 9077.25341 8892.290712 9050.399711 8954.153064 8945.492448 9129.805543 1.032290628 0.95630974 0.972313559 0.940689934 0.994243893 0.973984678 0.991302571 0.980760545 0.979811936 1 13.15636842 -7.261255264 24.9999999 1.015248352 0.973128823 0.297246217 0.019873667 9.322211586 1265826.309 0.00314728 0.003719086 5.48E-08 7.261255264 -0.042119529 YVAQAHDKPR ddPTM_HeLa_Curcumin_4h_R1 1 YVAQAHDKPR 10 1 I3L0K7;Q12931-2;Q12931;I3L239 I3L0K7 TRAP1 "Heat shock protein 75 kDa, mitochondrial" 0 0 68.846 0.011506 483030 738.19 752.48 545.97 607.04 916.72 998.55 730.98 644.63 826.66 656.79 FALSE FALSE TRUE 679.7614826 817.5210182 566.2041285 604.5282293 905.7887127 791.439474 751.4893315 841.1747195 735.9774662 679.6134036 1.000217887 1.202920681 0.833126783 0.889517814 1.332799953 1.164543651 1.105760021 1.237725323 1.082935478 1 9.408570496 -5.766020403 24.99990413 0.996180528 1.199485036 0.469426824 0.108398723 74.97092652 409139.8046 0.015049354 0.027956275 1.71E-06 5.766020403 0.203304508 YVATLGVEVHPLVFHTNR ddPTM_HeLa_Curcumin_4h_R1 1 YVATLGVEVHPLVFHTNR 18 0 F5H018;B5MDF5;J3KQE5;P62826;H0YFC6 F5H018 RAN GTP-binding nuclear protein Ran 0 0 71.286 0.0044619 1082200 193.47 296.44 343.14 247.68 276.43 878.7 405.65 315.45 387.93 226.08 FALSE FALSE TRUE 178.1566454 322.0629527 355.8570703 246.6551658 273.1337528 696.447715 417.0314472 411.6292528 345.3750496 233.9362632 0.761560619 1.376712393 1.521171046 1.054369094 1.167556278 2.977083183 1.782671235 1.759578644 1.476363882 1 7.869971705 -5.429765611 7.943160065 0.993523839 2.13222552 0.509444905 0.411279575 0.143580127 11.01794382 0.056334036 0.126235444 3.72E-06 5.429765611 1.138701682 YVDEENS(ph)DGETSNHR ddPTM_HeLa_Curcumin_4h_R1 2 YVDEENSDGETSNHR 15 0 H0YFD2;F8WFC1;A0A494C108;Q8N9T8;H0YH26 H0YFD2 KRI1 Protein KRI1 homolog 1 0 YVDEENS(1)DGETSNHR;YVDEENS(1)DGETSNHR ; 213.64 1.80E-14 121249000 16478.1 14492.6 11757.3 11493.5 22658.9 36266 18377.8 10187.1 22075.7 14302.7 TRUE FALSE FALSE 15173.841 15745.27577 12193.03588 11445.94294 22388.70742 28744.0228 18893.43161 13293.09989 19654.05094 14799.71776 1.025279079 1.063890273 0.823869487 0.773389272 1.51277935 1.942200741 1.276607562 0.898199554 1.32800174 1 13.85328204 -5.750600302 24.99741973 0.985963128 1.436297936 0.334616581 0.27804784 163.9789109 378170.7132 0.037557839 0.074528608 1.78E-06 5.750600302 0.450334808 YVDIAIPCNNK ddPTM_HeLa_Curcumin_4h_R1 2 YVDIAIPCNNK 11 0 C9J9K3;A0A0C4DG17;P08865 C9J9K3 RPSA 40S ribosomal protein SA 0 0 ; ; 179.8 1.29E-11 8025600 9683.2 7566.9 7996.5 8157.9 8182.8 10982.1 8511.8 8052.9 9043.2 7831.9 FALSE FALSE TRUE 8916.764502 8220.949119 8292.857324 8124.144771 8085.225454 8704.288666 8750.6182 10508.19214 8051.183585 8104.057942 1.100283903 1.014423783 1.023296894 1.002478614 0.997676166 1.074065453 1.079782285 1.296658071 0.99347557 1 12.98442877 -4.09231928 1.833935957 1.038423991 1.473469867 0.840527589 0.035003212 0.525770919 1.233702758 0.006154438 0.452025124 8.09E-05 4.09231928 0.435045876 YVEVS(ph)PATER ddPTM_HeLa_Curcumin_4h_R1 2 YVEVSPATER 10 0 Q9NTZ6 Q9NTZ6 RBM12 RNA-binding protein 12 1 0 YVEVS(0.995)PAT(0.005)ER;YVEVS(0.974)PAT(0.026)ER ; 144.7 0.0011871 21108000 5395.8 5058.7 4751.2 5662.5 4764.7 5689.8 4669.2 5047.1 4997.7 4678.1 TRUE FALSE FALSE 4968.716736 5495.951487 4927.283652 5639.070075 4707.884064 4509.671343 4800.205185 6585.937556 4449.464814 4840.663627 1.026453627 1.135371493 1.017894246 1.164937395 0.972569967 0.93162254 0.991641964 1.360544352 0.91918488 1 12.24098913 -4.258267016 24.92344439 1.02234456 1.360544482 0.653661889 0.074790603 125.7264531 987710.7219 0.009266773 0.088863243 5.52E-05 4.258267016 0.338199921 YVGFGNT(ph)PPPQK ddPTM_HeLa_Curcumin_4h_R1 1 YVGFGNTPPPQK 12 0 F8VWH9;Q8N6T3-5;Q8N6T3;Q8N6T3-2;Q8N6T3-4;E5RHT6;E5RHC5;F8W1U7;Q8N6T3-3 F8VWH9 ARFGAP1 ADP-ribosylation factor GTPase-activating protein 1 1 0 YVGFGNT(1)PPPQK 107.17 0.018618 18050000 2333.2 1850.3 1976.1 1824.4 2110.4 2766.9 2779.5 1519.1 2012.3 1698.7 TRUE FALSE FALSE 2148.524758 2010.231687 2049.336004 1816.851116 2085.234858 2193.013751 2857.485289 1982.266597 1791.555725 1757.729699 1.22232944 1.143652342 1.165899402 1.033635102 1.186322823 1.247639926 1.625668208 1.127742564 1.019244157 1 10.77949752 -1 0.042953451 0.471437432 2.462216423 0.323302343 0.1398122 531.0229802 1.750789871 21.51855993 75.00833306 0.1 1 1.99077899 YVIS(ph)DEEEEDDD ddPTM_HeLa_Curcumin_4h_R1 4 YVISDEEEEDDD 12 0 Q8WVC0-2;Q8WVC0 Q8WVC0-2 LEO1 RNA polymerase-associated protein LEO1 1 0 YVIS(1)DEEEEDDD;YVIS(1)DEEEEDDD;YVIS(1)DEEEEDDD;YVIS(1)DEEEEDDD ;;; 141.1 0.0011396 71897800 8062.1 6636 6396.5 7300.91 7219.54 7938.48 6584.75 6014.59 7929.6 6939.2 TRUE FALSE FALSE 7423.976278 7209.586271 6633.559917 7270.700769 7133.451701 6291.949763 6769.500363 7848.410803 7059.742719 7180.336683 1.0339315 1.004073568 0.923850818 1.012584937 0.993470364 0.876275033 0.94278314 1.093042172 0.983204971 1 12.80983578 -6.981780353 24.69051909 1.016180019 0.96996071 0.0607197 0.055519893 314.3526622 425996.0746 0.008626936 0.011336921 1.04E-07 6.981780353 -0.046219309 YVVACK(ac)EPK ddPTM_HeLa_Curcumin_4h_R1 2 YVVACKEPK 9 1 H3BN84;Q96ES7 H3BN84 CCDC101 SAGA-associated factor 29 homolog 0 1 ; YVVACK(1)EPK;YVVACK(1)EPK 159.28 3.17E-08 12819000 10540.1 5897.6 8835 7510.4 8095.7 12972.4 10433.4 9042.6 8502.7 7273.6 FALSE TRUE FALSE 9705.839963 6407.362265 9162.432872 7479.323955 7999.164065 10281.77801 10726.13312 11799.64711 7569.975083 7526.357059 1.289580057 0.851323185 1.217379511 0.993750881 1.062820167 1.366102874 1.42514274 1.567776684 1.00579537 1 12.87773602 -5.036085139 2.492450846 1.108680053 1.502036549 0.663375921 0.126803629 0.16314349 1.981233641 0.020445278 0.070794463 9.20E-06 5.036085139 0.393356497 YVWLVYEQDRPLKCDEPILSNR ddPTM_HeLa_Curcumin_4h_R1 1 YVWLVYEQDRPLKCDEPILSNR 22 2 P30086 P30086 PEBP1 Phosphatidylethanolamine-binding protein 1;Hippocampal cholinergic neurostimulating peptide 0 0 44.054 0.019667 16565000 299.65 149.2 269.71 287.3 361.16 647.92 347.36 618.39 464.03 372.3 FALSE FALSE TRUE 275.9323863 162.0961832 279.7056899 286.1112287 356.8534029 513.5340884 357.1059867 806.9342643 413.1270699 385.2373973 0.716265836 0.420769594 0.726060585 0.742688095 0.926320771 1.333032805 0.926976429 2.094641564 1.072396068 1 8.589603951 -1.448569626 0.866983997 0.818429035 200 0.724152426 0.227862794 120.0658788 0.706598967 0.035987344 46676.74558 0.035598391 1.448569626 199.181571 up YWEEETVPTTAGAS(ph)PGPPR ddPTM_HeLa_Curcumin_4h_R1 2 YWEEETVPTTAGASPGPPR 19 0 O15213 O15213 WDR46 WD repeat-containing protein 46 1 0 YWEEETVPT(0.256)T(0.256)AGAS(0.487)PGPPR;YWEEET(0.001)VPT(0.068)T(0.068)AGAS(0.863)PGPPR ; 109.72 0.00068812 6236000 889.27 832.54 953.62 1041.71 966.14 1193 961.97 588.94 1092.51 814.54 TRUE FALSE FALSE 818.8833411 904.5010479 988.9619961 1037.39968 954.6194115 945.5583521 988.9602892 768.5050949 972.6643863 842.8452044 0.971570268 1.073152037 1.173361361 1.230830614 1.132615344 1.121864783 1.173359336 0.911798621 1.15402494 1 9.719123882 -7.071101078 3.822638349 0.986883837 1.131214473 0.04590943 0.095026605 0.163806028 4.636191347 0.012734216 0.015970923 8.49E-08 7.071101078 0.144330636 YWGPASPT(ph)HK ddPTM_HeLa_Curcumin_4h_R1 1 YWGPASPTHK 10 0 A0A3B3ISQ4;Q9H6S3-2;Q9H6S3;Q9H6S3-3 A0A3B3ISQ4 EPS8L2 Epidermal growth factor receptor kinase substrate 8-like protein 2 1 0 YWGPAS(0.198)PT(0.802)HK 121.36 0.012555 76254000 3072.9 2237.1 2539.9 2553.1 2694.8 3327.8 2802.5 3036.3 2652.9 2468.5 TRUE FALSE FALSE 2829.676722 2430.464956 2634.030928 2542.535949 2662.66627 2637.576768 2881.130607 3962.053893 2361.883507 2554.280191 1.107817667 0.951526369 1.031222392 0.995402132 1.04243312 1.032610587 1.127961849 1.551143021 0.924676751 1 11.31870107 -4.247167743 2.664036155 1.037983209 1.664385254 0.899354861 0.053571395 0.103905122 0.932055971 0.006952804 0.145962699 5.66E-05 4.247167743 0.626402046 YWPQEAGEYAVHVLCNSEDIR ddPTM_HeLa_Curcumin_4h_R1 2 YWPQEAGEYAVHVLCNSEDIR 21 0 P21333-2;P21333;Q60FE5;A0A087WWY3 P21333-2;Q60FE5 FLNA Filamin-A 0 0 ; ; 116.94 1.02E-05 104586000 1398.94 801.52 1111.48 785.13 1080.72 1658.65 1146.15 1069.37 1020.08 1103.65 FALSE FALSE TRUE 1288.212423 870.7998173 1152.672427 781.8813401 1067.83312 1314.627293 1178.307884 1395.41599 908.1797761 1142.001755 1.12803016 0.762520559 1.009343831 0.684658615 0.935053834 1.151160484 1.031791658 1.221903542 0.795252522 1 10.15734915 -4.040458186 1.28700553 1.004066061 1.399219207 0.140781892 0.156128392 3.504732263 3.423951433 0.022849739 2.078156485 9.11E-05 4.040458186 0.395153146 YWQQVIDMNDYQR ddPTM_HeLa_Curcumin_4h_R1 1 YWQQVIDMNDYQR 13 0 O60701;O60701-3;O60701-2 O60701 UGDH UDP-glucose 6-dehydrogenase 0 0 117.71 0.0015336 0 747.95 592.79 708.07 516.71 600.83 1008.6 797.05 747.69 710.01 706.86 FALSE FALSE TRUE 688.7489683 644.0281262 734.3116971 514.5719909 593.6654947 799.4049907 819.4130778 975.6572391 632.1236794 731.4233324 0.941655725 0.880513511 1.003948964 0.703521433 0.811657857 1.092944339 1.120299342 1.333915936 0.864237783 1 9.514562839 -4.579439887 1.704266618 0.939281289 1.343344671 0.643628064 0.101308078 0.293766087 1.272619956 0.01532454 0.157907687 2.63E-05 4.579439887 0.404063382 YYDDIYFDS(ph)DS(ph)EDEDRAVQVTK ddPTM_HeLa_Curcumin_4h_R1 1 YYDDIYFDSDSEDEDRAVQVTK 22 1 G3V2W9;A0A087X060;Q56P03 G3V2W9 EAPP E2F-associated phosphoprotein 2 0 Y(0.007)Y(0.007)DDIY(0.329)FDS(0.826)DS(0.826)EDEDRAVQVT(0.005)K 73.294 0.001356 25137000 3336 2920.8 3076 3273.2 3265.7 3360.1 3191.4 3164.4 4027.7 2947 TRUE FALSE FALSE 3071.95208 3173.260937 3189.999266 3259.656366 3226.75866 2663.177384 3280.942095 4129.210993 3585.871387 3049.408031 1.007392926 1.040615393 1.046104435 1.068947262 1.058159035 0.873342418 1.075927545 1.354102485 1.17592377 1 11.57431349 -4.29485443 3.78860911 1.009980428 1.378378639 0.609755697 0.074188669 0.070668284 1.903170773 0.006956633 0.067944952 5.07E-05 4.29485443 0.368398211 YYDSRPGGYGYGYGR ddPTM_HeLa_Curcumin_4h_R1 1 YYDSRPGGYGYGYGR 15 1 P98179 P98179 RBM3 RNA-binding protein 3 0 0 121.21 0.0010628 116720000 2611.8 1419.4 2128.5 1264.1 2070.8 3822.1 2499 2232.3 2655.5 2143.1 FALSE FALSE TRUE 2405.073274 1542.086611 2207.384082 1258.869489 2046.107062 3029.353376 2569.115214 2912.917994 2364.198294 2217.572565 1.084552231 0.69539398 0.995405569 0.567679051 0.922678741 1.366067304 1.158525883 1.313561522 1.066119923 1 11.1147656 -5.267798394 24.74427807 0.967767127 1.267299004 0.483244066 0.168858655 354.1262988 1377983.946 0.025934805 0.059367895 5.40E-06 5.267798394 0.299531877 YYDVMSDEEIER ddPTM_HeLa_Curcumin_4h_R1 1 YYDVMSDEEIER 12 0 O15460-2;O15460 O15460-2 P4HA2 Prolyl 4-hydroxylase subunit alpha-2 0 0 136.49 0.013935 8276600 928.25 627.45 910.59 709.89 1032.3 1586.2 940.79 502.29 876.79 703.65 FALSE FALSE TRUE 854.778033 681.6839821 944.3372664 706.9526633 1019.990497 1257.20424 967.1860354 655.4359087 780.6083306 728.1017851 1.17398151 0.936248195 1.296985237 0.97095307 1.400889982 1.726687485 1.328366521 0.90019819 1.072114293 1 9.507996336 -5.751740302 24.98092884 1.082863751 1.365962954 0.269349035 0.210913489 197.5665314 508848.3734 0.030398246 0.060184383 1.77E-06 5.751740302 0.283099203 TTKPPYPGS(ph)PVKYR ddPTM_HeLa_Curcumin_4h_R1 1 TTKPPYPGSPVKYR 14 2 Q96T17;Q96T17-2;Q96T17-5;Q96T17-4 Q96T17 MAP7D2 MAP7 domain-containing protein 2 1 0 T(0.06)T(0.015)KPPY(0.009)PGS(0.901)PVKY(0.015)R 51.127 0.018908 143920000 3240.2 2476.3 2659.8 2867.1 2494.4 3584.1 2622.6 1214.5 4023 3409.7 TRUE FALSE FALSE 2983.734751 2690.340338 2758.374528 2855.2367 2464.655909 2840.717259 2696.183098 1584.795459 3581.686965 3528.186821 0.845685022 0.762527744 0.781810791 0.809264601 0.698561622 0.805149331 0.764183768 0.449181276 1.015163637 1 11.78471124 -3.457038738 0.095266223 1.199027763 4.72E-12 0.721646385 0.079034549 29.80557489 0.363062969 0.95830731 4.9599181 0.000349109 3.457038738 -1.199027763 down HGS(ph)GADSDY(ph)ENTQSGDPLLGLEGKR ddPTM_HeLa_Curcumin_4h_R1 1 HGSGADSDYENTQSGDPLLGLEGKR 25 1 J3QRU8;Q9Y2X7;Q9Y2X7-3;A0A0C4DGN6;J3QL89 J3QRU8 GIT1 ARF GTPase-activating protein GIT1 2 0 HGS(0.923)GADS(0.086)DY(0.98)ENT(0.01)QS(0.001)GDPLLGLEGKR 102.46 5.01E-07 13741000 4040.4 3118.2 2648.2 3514.8 2711.2 3805.4 2897.1 1367.2 4770.9 3639.1 TRUE FALSE FALSE 3720.598077 3387.723314 2746.344622 3500.256689 2678.870711 3016.117144 2978.384829 1784.052986 4247.544206 3765.558454 0.988060104 0.899660264 0.729332622 0.929545174 0.711413923 0.800974724 0.790954347 0.47378178 1.127998478 1 11.87864813 -3.408718811 0.256006956 1.025540196 4.81E-15 0.712042734 0.094267647 5.727953649 0.206407461 0.050498062 1.997294632 0.000390195 3.408718811 -1.025540196 down YYGGGS(ph)EGGRAPK ddPTM_HeLa_Curcumin_4h_R1 1 YYGGGSEGGRAPK 13 1 P14866 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 1 0 YYGGGS(1)EGGRAPK 148.89 0.0057502 4384000 867.23 622.24 621.16 752.65 644.9 758.59 1032.5 437.62 877.67 906.93 TRUE FALSE FALSE 798.5878304 676.023653 644.180736 749.5357337 637.2099887 601.2498829 1061.469171 571.0483234 781.3917968 938.44575 0.850968562 0.720365192 0.686433644 0.798699055 0.679005674 0.640686884 1.131092736 0.608504352 0.832644611 1 9.874129537 -8.136692336 0.874916658 0.977153864 0.760616738 0.132531971 0.146954828 0.456694845 0.748271237 0.043551878 0.030268682 7.30E-09 8.136692336 -0.216537126 YYGGGSEGGR ddPTM_HeLa_Curcumin_4h_R1 2 YYGGGSEGGR 10 0 P14866 P14866 HNRNPL Heterogeneous nuclear ribonucleoprotein L 0 0 ; ; 124.08 0.0023249 10142800 2693.7 2415.3 2329.82 2209.4 2159.1 2891.5 2126.8 2221.7 2312.4 2481 FALSE FALSE TRUE 2480.490803 2624.06777 2416.165179 2200.258088 2133.354143 2291.770306 2186.472284 2899.086103 2058.735505 2567.214565 0.966218732 1.022145872 0.94116215 0.857060457 0.830999548 0.892706958 0.851690511 1.129273003 0.801933556 1 11.32598816 -6.532518787 8.06845045 0.986293751 0.902900784 0 0.098543552 0.164735431 76.87812608 0.011806066 0.01697877 2.93E-07 6.532518787 -0.083392968 YYITIIDAPGHR ddPTM_HeLa_Curcumin_4h_R1 1 YYITIIDAPGHR 12 0 A0A2U3TZH3;Q05639;A0A2R8Y488;A0A2R8Y660;A0A2R8YDN5 A0A2U3TZH3 EEF1A2 Elongation factor 1-alpha 2 0 0 80.014 0.0129 783350 247.85 264.57 373.36 299.53 405.79 421.52 375.71 192.03 265.5 376.98 FALSE FALSE TRUE 228.232411 287.4382519 387.19705 298.2906242 400.9512193 334.0920005 386.2514114 250.579063 236.3753142 390.0800269 0.585091251 0.736869955 0.992609268 0.764690842 1.027869133 0.85647041 0.990185051 0.642378604 0.605966207 1 8.60762632 -6.783629114 24.95351003 0.793556319 0.88462849 0.131357994 0.155455126 587.3980102 660557.2638 0.029548246 0.038850892 1.65E-07 6.783629114 0.09107217 YYK(ac)VDENGK ddPTM_HeLa_Curcumin_4h_R1 2 YYKVDENGK 9 1 P62979;A0A2R8Y422 P62979 RPS27A Ubiquitin-40S ribosomal protein S27a;Ubiquitin;40S ribosomal protein S27a 0 1 ; YYK(1)VDENGK;YYK(1)VDENGK 172.59 5.53E-12 11552800 5146.6 5755.5 4240.5 4100 5834.4 8458.3 6274.7 6342.4 9095.6 4619.3 FALSE TRUE FALSE 4739.241179 6252.979774 4397.65666 4083.035286 5764.828591 6703.953235 6450.751195 8276.168563 8097.835436 4779.820331 0.991510319 1.308203937 0.920046436 0.854223591 1.206076419 1.402553395 1.349580266 1.7314811 1.694171512 1 12.22274067 -4.6406585 0.835881831 1.005103099 1.855728645 0.239663184 0.25604928 0.558357415 0.399219781 0.02158941 0.385702373 2.29E-05 4.6406585 0.850625546 YYMSDDISRDS(ph)DGMDEQCR ddPTM_HeLa_Curcumin_4h_R1 3 YYMSDDISRDSDGMDEQCR 19 1 P46100-5;P46100-3;P46100-4;P46100;A0A096LNL9;P46100-6;A0A096LNW1;A0A096LNL6;A0A096LNN3 P46100-5 ATRX Transcriptional regulator ATRX 1 0 YYMS(0.003)DDIS(0.076)RDS(0.921)DGMDEQCR;YYMS(0.046)DDIS(0.207)RDS(0.746)DGMDEQCR;YYMSDDIS(0.171)RDS(0.829)DGMDEQCR ;; 89.311 0.00094888 29706300 4761.2 4042.7 4222.3 4543.7 4055.4 5396.3 3483.75 3118.41 4538.1 4257.5 TRUE FALSE FALSE 4384.345996 4392.132974 4378.782152 4524.899373 4007.042004 4277.046551 3581.494649 4069.198854 4040.281784 4405.447808 0.995210064 0.996977643 0.993947118 1.027114511 0.909565197 0.970853983 0.812969488 0.923674285 0.917110351 1 12.10507296 -5.272181186 1.374385223 0.998685745 0.874069683 0.412482539 0.046640532 0.20128355 0.696664632 0.005103657 0.020342752 5.34E-06 5.272181186 -0.124616062 YYPTEDVPR ddPTM_HeLa_Curcumin_4h_R1 2 YYPTEDVPR 9 0 Q02878;F8VZ45;U3KQR5;F8VR69 Q02878 RPL6 60S ribosomal protein L6 0 0 ; ; 121.62 0.0012294 17311000 5626.5 5865.2 5586.9 5915 5926.8 7457.3 5893.7 5608.8 6928.4 5334.2 FALSE FALSE TRUE 5181.156588 6372.161753 5793.955429 5890.525297 5856.126781 5910.571919 6059.06136 7318.8973 6168.371854 5519.563053 0.938689628 1.154468514 1.049712699 1.067208625 1.060976517 1.070840547 1.097742938 1.325992154 1.117547131 1 12.43033835 -1 0.376308606 0.982351017 5.073717461 0.411786242 0.074747536 27.03136215 0.32966297 0.017593034 81.37237234 0.1 1 4.091366444 SPSFGDPQLS(ph)PEAR ddPTM_HeLa_Curcumin_4h_R1 2 SPSFGDPQLSPEAR 14 0 O95425-3;A0A6I8PIX7;O95425-2;O95425;O95425-4 O95425-3 SVIL Supervillin 1 0 SPSFGDPQLS(1)PEAR;SPSFGDPQLS(1)PEAR ; 169.98 0.00020365 27441000 2590.7 2299.4 2441 2685.3 3293 3757 3088.4 3536.1 2559.3 2126.19 TRUE FALSE FALSE 2385.643361 2498.14989 2531.465607 2674.18894 3253.733126 2977.75585 3175.052192 4614.240612 2278.551193 2200.074944 1.084346407 1.135483996 1.150626988 1.215499021 1.478919222 1.353479279 1.44315638 2.09731065 1.035669807 1 11.10333695 -1 0.365398062 1.028445189 13.45955876 0.893021975 0.101021284 11.74089621 0.144951928 0.026825218 103.3111366 0.1 1 12.43111357 up TVTDVSTIDGNAAELVSGRPVSDT(ph)TEPSSPEGK ddPTM_HeLa_Curcumin_4h_R1 1 TVTDVSTIDGNAAELVSGRPVSDTTEPSSPEGK 33 1 C9JA33;B1ALY0;Q8IXS6;Q8IXS6-2 C9JA33 PALM2;PALM2-AKAP2 Paralemmin-2 1 0 TVTDVSTIDGNAAELVS(0.006)GRPVS(0.15)DT(0.683)T(0.15)EPS(0.011)S(0.001)PEGK 94.207 1.20E-10 5366500 2229 1963.7 2407.3 2126.9 2846.9 2761.8 2591 3689.8 1878.7 1480.1 TRUE FALSE FALSE 2052.572298 2133.433478 2496.516656 2118.099451 2812.952577 2188.971548 2663.696487 4814.803034 1672.61131 1531.533365 1.340207367 1.393004898 1.630076571 1.382992692 1.836690366 1.429267947 1.739235036 3.143779394 1.092115489 1 10.58076108 -1 0.582858928 1.221415363 99.28853926 0.818917001 0.243119175 45.03631521 0.339651487 0.0477179 5614.011089 0.1 1 98.0671239 up YYS(ph)PCEEHPAETNQNEGSESGTIR ddPTM_HeLa_Curcumin_4h_R1 2 YYSPCEEHPAETNQNEGSESGTIR 24 0 A0A2R8YFR7;Q12774;A0A5F9ZGZ6 A0A2R8YFR7 ARHGEF5 Rho guanine nucleotide exchange factor 5 1 0 Y(0.038)Y(0.038)S(0.922)PCEEHPAET(0.003)NQNEGSESGTIR;Y(0.124)Y(0.124)S(0.753)PCEEHPAETNQNEGSESGTIR ; 99.414 8.29E-06 7087400 3607.54 3388.9 3559.5 3600 3712.1 3038.52 2957.79 2259.03 4401.8 3779.7 TRUE FALSE FALSE 3321.999402 3681.821415 3691.418201 3585.104154 3667.835632 2408.296701 3040.777627 2947.797848 3918.933553 3911.044294 0.849389358 0.941390876 0.943844642 0.916661609 0.937814905 0.615768199 0.777484835 0.75371119 1.002017175 1 11.93333816 -5.279207868 24.90661552 0.929039269 0.721837753 0.764366867 0.057158166 317.4320456 444953.5079 0.009358978 0.020968349 5.26E-06 5.279207868 -0.207201516 YYSDS(ph)DDELT(ph)VEQR ddPTM_HeLa_Curcumin_4h_R1 1 YYSDSDDELTVEQR 14 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 2 0 Y(0.001)YS(0.206)DS(0.814)DDELT(0.979)VEQR 182.72 0.00041508 20295000 2089.8 1902.2 1818.7 2219.6 1681.2 2511.2 1743.8 1149.8 2298.5 1474.9 TRUE FALSE FALSE 1924.390125 2066.617692 1886.102622 2210.415883 1661.152788 1990.348813 1792.726335 1500.368727 2046.360301 1526.152665 1.260942086 1.354135624 1.235854489 1.448358302 1.08845781 1.304161018 1.174670382 0.983105269 1.340862122 1 10.57568357 -9.161644117 0.945903067 1.002080717 1.237694346 0 0.161905341 0.495783422 0.809227089 0.07736444 0.02294806 6.89E-10 9.161644117 0.235613629 YYSDS(ph)DDELTVEQR ddPTM_HeLa_Curcumin_4h_R1 1 YYSDSDDELTVEQR 14 0 Q8NFC6 Q8NFC6 BOD1L1 Biorientation of chromosomes in cell division protein 1-like 1 1 0 YYS(0.014)DS(0.986)DDELTVEQR 198.81 1.24E-06 15865000 1644.4 1282.5 1556.5 1454 1279.7 1472.5 1193.2 2530.3 1714.9 1190.9 TRUE FALSE FALSE 1514.244005 1393.353585 1614.185259 1447.983733 1264.440413 1167.086902 1226.677981 3301.776822 1526.77976 1232.283686 1.228811208 1.130708457 1.309913681 1.175040901 1.026095231 0.947092714 0.995450962 2.679396683 1.238983992 1 10.2671187 -4.258954335 24.99908352 1.107672632 2.679397236 0.94229284 0.115980935 40.54423527 407842.4543 0.017762156 0.161068325 5.51E-05 4.258954335 1.571724604 YYVTIIDAPGHR ddPTM_HeLa_Curcumin_4h_R1 4 YYVTIIDAPGHR 12 0 Q5VTE0;P68104;A0A087WVQ9;A0A087WV01;A6PW80;Q5JR01 Q5VTE0 EEF1A1P5;EEF1A1 Putative elongation factor 1-alpha-like 3;Elongation factor 1-alpha 1;Elongation factor 1-alpha 0 0 ;;; ;;; 155.33 6.51E-06 774200000 18954.2 15791.7 17274.1 14754.3 17152.3 22229.3 18695.1 18373.8 17026.7 15333.3 FALSE FALSE TRUE 17453.95507 17156.66418 17914.29334 14693.25062 16947.77003 17618.6926 19219.63419 23975.88704 15158.91361 15866.13103 1.100076322 1.081338869 1.129090218 0.92607647 1.068172826 1.11045929 1.211362376 1.511136331 0.955425968 1 13.95366275 -4.132987618 1.334769726 1.049416204 1.817323818 0.84676437 0.061151344 0.469999619 0.581516084 0.008629846 0.527440973 7.36E-05 4.132987618 0.767907614